Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

why do fibroblast,endothelial,epithelial exit in immune_ALL_High_model? #139

Open
echovv opened this issue Nov 13, 2024 · 1 comment
Open

Comments

@echovv
Copy link

echovv commented Nov 13, 2024

Hi,
Super helpful tools! Here is my question:
When I annotate the human spleen dataset using the immune_ALL_High_model, I get the figure below. I noticed that a portion of the fibroblast cells remains unassigned. I'm wondering what could be the reason for this. I might think is the different property of fibroblast, so I checked the relevant scientific paper, but it doesn't mention any stromal cells. So, where do the trained fibroblasts originate from, and what is the tissue source in this case?
image

Ziwei

@ChuanXu1
Copy link
Collaborator

ChuanXu1 commented Dec 2, 2024

@echovv, Fibroblasts and other non-immune cells act as umbrella categories to provide flexibility for annotating potential non-immune cells in the query data. Fibroblasts used in the training data are from thymus.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants