From ee0af1c19ce64071c38b8114f973326681c09573 Mon Sep 17 00:00:00 2001 From: TieuLongPhan Date: Mon, 22 Jul 2024 11:53:50 +0200 Subject: [PATCH] clean repo --- Data/DPO/USPTO_50K.csv | 50017 ---------------- .../Good_hydrogen/Log/hier_rule_0_log.txt | 61 - .../Good_hydrogen/Log/hier_rule_1_log.txt | 61 - .../Good_hydrogen/Log/hier_rule_2_log.txt | 61 - .../Good_hydrogen/Log/hier_rule_3_log.txt | 61 - .../Good_hydrogen/Log/rules_r0_log.txt | 61 - .../Good_hydrogen/Log/rules_r1_log.txt | 61 - .../Good_hydrogen/Log/rules_r2_log.txt | 61 - .../Good_hydrogen/Log/rules_r3_log.txt | 61 - .../USPTO_50K/Hydrogen/Log/rules_r0_log.txt | 61 - .../USPTO_50K/Hydrogen/Log/rules_r1_log.txt | 61 - .../USPTO_50K/Hydrogen/Log/rules_r2_log.txt | 61 - .../USPTO_50K/Hydrogen/Log/rules_r3_log.txt | 61 - .../Hydrogen/USPTO_50K_pipeline_log.log | 87 - .../Non_hydrogen/Log/rules_r0_log.txt | 61 - .../Non_hydrogen/Log/rules_r1_log.txt | 61 - .../Non_hydrogen/Log/rules_r2_log.txt | 61 - .../Non_hydrogen/Log/rules_r3_log.txt | 61 - .../Non_hydrogen/USPTO_50K_pipeline_log.log | 6 - .../Complete/USPTO_balance_pipeline.log | 47 - .../Raw/USPTO_balance_pipeline.log | 6 - Data/DPO/USPTO_balance/aam_log.txt | 3027 - Data/DPO/USPTO_balance/balance_log.txt | 173 - .../Complete/USPTO_unbalance_pipeline.log | 47 - .../Raw/USPTO_unbalance_pipeline.log | 6 - Data/DPO/USPTO_unbalance/aam_log.txt | 48 - Data/{USPTO_50K => }/USPTO_50K.csv | 0 Data/{USPTO_50K => }/USPTO_50K_original.csv | 0 Docs/Analysis/_templates_analysis.ipynb | 15507 +---- SynTemp/SynITS/its_refinement.py | 4 +- SynTemp/__main__.py | 2 +- 31 files changed, 329 insertions(+), 69624 deletions(-) delete mode 100644 Data/DPO/USPTO_50K.csv delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_0_log.txt delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_1_log.txt delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_2_log.txt delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_3_log.txt delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r0_log.txt delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r1_log.txt delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r2_log.txt delete mode 100644 Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r3_log.txt delete mode 100644 Data/DPO/USPTO_50K/Hydrogen/Log/rules_r0_log.txt delete mode 100644 Data/DPO/USPTO_50K/Hydrogen/Log/rules_r1_log.txt delete mode 100644 Data/DPO/USPTO_50K/Hydrogen/Log/rules_r2_log.txt delete mode 100644 Data/DPO/USPTO_50K/Hydrogen/Log/rules_r3_log.txt delete mode 100644 Data/DPO/USPTO_50K/Hydrogen/USPTO_50K_pipeline_log.log delete mode 100644 Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r0_log.txt delete mode 100644 Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r1_log.txt delete mode 100644 Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r2_log.txt delete mode 100644 Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r3_log.txt delete mode 100644 Data/DPO/USPTO_50K/Non_hydrogen/USPTO_50K_pipeline_log.log delete mode 100644 Data/DPO/USPTO_balance/Complete/USPTO_balance_pipeline.log delete mode 100644 Data/DPO/USPTO_balance/Raw/USPTO_balance_pipeline.log delete mode 100644 Data/DPO/USPTO_balance/aam_log.txt delete mode 100644 Data/DPO/USPTO_balance/balance_log.txt delete mode 100644 Data/DPO/USPTO_unbalance/Complete/USPTO_unbalance_pipeline.log delete mode 100644 Data/DPO/USPTO_unbalance/Raw/USPTO_unbalance_pipeline.log delete mode 100644 Data/DPO/USPTO_unbalance/aam_log.txt rename Data/{USPTO_50K => }/USPTO_50K.csv (100%) rename Data/{USPTO_50K => }/USPTO_50K_original.csv (100%) diff --git a/Data/DPO/USPTO_50K.csv b/Data/DPO/USPTO_50K.csv deleted file mode 100644 index c4ae9d5..0000000 --- a/Data/DPO/USPTO_50K.csv +++ /dev/null @@ -1,50017 +0,0 @@ -id,class,reactions -US05849732,6,COC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)Nc1cc(OC)cc(C(C)(C)C)c1O>>COC(=O)[C@H](CCCCN)NC(=O)Nc1cc(OC)cc(C(C)(C)C)c1O -US20120114765A1,2,Nc1cccc2cnccc12.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(Nc1cccc2cnccc12)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US08003648B2,1,CCNCC.Cc1nc(-c2ccc(C=O)cc2)sc1COc1ccc([C@H](CC(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)c2ccon2)cc1>>CCN(CC)Cc1ccc(-c2nc(C)c(COc3ccc([C@H](CC(=O)N4C(=O)OC[C@@H]4Cc4ccccc4)c4ccon4)cc3)s2)cc1 -US09045475B2,1,CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NCC5CNC5)c([N+](=O)[O-])c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1.O=C(CF)CF>>CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NCC5CN(C(CF)CF)C5)c([N+](=O)[O-])c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1 -US08188098B2,2,CCOc1ccc(Oc2ncnc3c2cnn3C2CCNCC2)c(F)c1.O=C(Cl)OC1CCCC1>>CCOc1ccc(Oc2ncnc3c2cnn3C2CCN(C(=O)OC3CCCC3)CC2)c(F)c1 -US20140275084A1,3,Cn1cnc(-c2cc(C#N)ccn2)c1Br.OB(O)c1ccc(-n2cccn2)cc1>>Cn1cnc(-c2cc(C#N)ccn2)c1-c1ccc(-n2cccn2)cc1 -US20110224204A1,3,CC1(C)OB(c2ccc(OCc3ccc4ccccc4n3)cc2)OC1(C)C.N#Cc1ccc(OC2CCCCO2)c(Br)c1>>N#Cc1ccc(OC2CCCCO2)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1 -US20130005716A1,7,COc1ccc(C(=O)Cc2c(Cl)c[n+]([O-])cc2Cl)c2c1OC1(CCCC1)O2>>COc1ccc(C(O)Cc2c(Cl)c[n+]([O-])cc2Cl)c2c1OC1(CCCC1)O2 -US20130172384A1,2,CC(C)(C)OC(=O)NN.O=C(O)c1ccc(Br)cc1Cl>>CC(C)(C)OC(=O)NNC(=O)c1ccc(Br)cc1Cl -US20050277619A1,1,CCOP(=O)(CO)OCC.Nc1ncnc2c1nc(CBr)n2CCc1ccccc1>>CCOP(=O)(COCc1nc2c(N)ncnc2n1CCc1ccccc1)OCC -US20110263607A1,6,CC(C)(C)OC(=O)CONC(=O)NCc1cccc2ccccc12>>O=C(O)CONC(=O)NCc1cccc2ccccc12 -US06372735B1,6,CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1C(=O)c1ccc(OC)c(OC)c1>>CCOC(=O)c1nn[nH]c1C(=O)c1ccc(OC)c(OC)c1 -US20100003305A1,2,CC(C)[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)O.COC(=O)CN>>COC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C -US07820673B2,1,NC1CCN(Cc2ccccc2)CC1.O=Cc1c[nH]cn1>>c1ccc(CN2CCC(NCc3c[nH]cn3)CC2)cc1 -US20050148627A1,1,BrCc1ccccc1.Oc1ccc(O)c(Br)c1>>Oc1ccc(OCc2ccccc2)c(Br)c1 -US20070225349A1,6,COc1ccc(-c2nn(C(C)C)c3c(Cl)cccc23)cc1>>CC(C)n1nc(-c2ccc(O)cc2)c2cccc(Cl)c21 -US05834461,2,Cc1ccccc1C(=O)Cl.Nc1ccc(C(=O)N2Cc3ccccc3Sc3ncccc32)cc1>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3ccccc3Sc3ncccc32)cc1 -US20150057271A1,1,Fc1ccc(C(F)(F)F)cc1Br.c1ccc2c(c1)NCCO2>>FC(F)(F)c1ccc(N2CCOc3ccccc32)c(Br)c1 -US05612288,1,CC(C)S.Fc1cccnc1F>>CC(C)Sc1ncccc1F -US20120202797A1,1,COC(=O)C(C)(C)CN1CCNCC1.Cc1cc2n(c1)Cc1cc(Cl)ccc1N=C2Cl>>COC(=O)C(C)(C)CN1CCN(C2=Nc3ccc(Cl)cc3Cn3cc(C)cc32)CC1 -US05866589,6,CCN(c1nc(F)ccc1NC(C)C)C1CCN(Cc2ccccc2)CC1>>CCN(c1nc(F)ccc1NC(C)C)C1CCNCC1 -US20110152240A1,3,O=C1CNC(=O)N1.O=Cc1cnn2c(NC3CC3)cc(NC3CCCC3)nc12>>O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(NC4CCCC4)nc23)N1 -US20060217346A1,1,CC(C)(C)OC(=O)C(Br)Oc1cc(Cl)cc(Cl)c1.C[O-]>>COC(Oc1cc(Cl)cc(Cl)c1)C(=O)OC(C)(C)C -US09133104B2,9,N.O=[N+]([O-])c1cccc(CBr)c1>>NCc1cccc([N+](=O)[O-])c1 -US20040224976A1,6,C[Si](C)(C)C#Cc1coc2ccc(C(=O)N[C@H]3CN4CCC3CC4)cc12>>C#Cc1coc2ccc(C(=O)N[C@H]3CN4CCC3CC4)cc12 -US05872117,2,CC(=O)OC(COCCO)c1cccc(Cl)c1.CS(=O)(=O)Cl>>CC(=O)OC(COCCOS(C)(=O)=O)c1cccc(Cl)c1 -US20090286778A1,2,Clc1cnc2nc1Nc1ccc(OCCC3CCNCC3)c(c1)CCc1cncc(c1)N2.O=C=NCc1ccco1>>O=C(NCc1ccco1)N1CCC(CCOc2ccc3cc2CCc2cncc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US05556977,1,Brc1ccc(OCc2ccccc2)cc1.O=C1CN(c2ccncc2)CCN1>>O=C1CN(c2ccncc2)CCN1c1ccc(OCc2ccccc2)cc1 -US20030232832A1,1,CC(C)(C)OC(=O)NCCCN.CCC(O)c1nn2cccc2c(=O)n1Cc1ccccc1>>CCC(NCCCNC(=O)OC(C)(C)C)c1nn2cccc2c(=O)n1Cc1ccccc1 -US08258134B2,6,COC(=O)C(CC1CCCC1)n1ncc(Oc2ccccc2C(C)=O)cc1=O>>CC(=O)c1ccccc1Oc1cnn(C(CC2CCCC2)C(=O)O)c(=O)c1 -US20110092461A1,2,Nc1ccc(Cl)c(-c2ccccn2)c1.O=C(O)c1ccc(-n2cncn2)nc1>>O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(-n2cncn2)nc1 -US04298535,3,C=C1C(=C)C2OC1C(=C)C2=C.C=CC(C)=O>>C=C1C(=C)C2OC1C1=C2CC(C(C)=O)CC1 -US06051731,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CCc1ccc(Br)cc1>>CCOC(=O)C=CCc1ccc(Br)cc1 -US20120142685A1,1,CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccnc(Cl)c3)cc3cnccc23)CC1.NC1CCOCC1>>CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccnc(NC4CCOCC4)c3)cc3cnccc23)CC1 -US08664216B2,1,C=O.Clc1ccc2c(c1)CNCc1nnc(Br)n1-2>>CN1Cc2cc(Cl)ccc2-n2c(Br)nnc2C1 -US04564609,2,CNC.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CN(C)C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 -US20120016029A1,1,CCOC(=O)Cc1ccc(OC)c(Oc2ccc([N+](=O)[O-])cc2CBr)c1.FC(F)(F)CS>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc([N+](=O)[O-])cc2CSCC(F)(F)F)c1 -US07964613B2,2,CC(C)(C)OC(=O)NCC1CCNCC1.O=S(=O)(Cl)c1cccc2cncc(Cl)c12>>CC(C)(C)OC(=O)NCC1CCN(S(=O)(=O)c2cccc3cncc(Cl)c23)CC1 -US20090081165A1,1,CCOC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.N[C@H]1CC[C@H](O)CC1>>CCOC(=O)c1ccc(N[C@@H]2CC[C@@H](O)CC2)c([N+](=O)[O-])c1 -US08404673B2,1,CC(=O)N1CCC(=O)CC1.COc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)N[C@@H]1CCCC[C@@H]1N>>COc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)N[C@@H]1CCCC[C@@H]1NC1CCN(C(C)=O)CC1 -US06888000B2,2,CCCCCc1nc2c(N)nc3ccccc3c2n1CCCCN.O=S(=O)(Cl)c1ccccc1>>CCCCCc1nc2c(N)nc3ccccc3c2n1CCCCNS(=O)(=O)c1ccccc1 -US07285558B2,2,CC(C)Cn1c(=O)n(C)c(=O)c2c(-c3cc(C(=O)O)cn3C)n(Cc3c[nH]c4ccc(Cl)cc34)nc21.CC(C)NCCN>>CC(C)Cn1c(=O)n(C)c(=O)c2c(-c3cc(C(=O)NCCNC(C)C)cn3C)n(Cc3c[nH]c4ccc(Cl)cc34)nc21 -US04006232,1,ClCCCN1CCN(c2ccccc2)CC1.O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1>>O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1CCCN1CCN(c2ccccc2)CC1 -US04927956,2,CC(=O)Cl.Cc1ccccc1O>>CC(=O)Oc1ccccc1C -US20100009970A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(C(=O)OC)cc21>>COC(=O)c1ccc2c(c1)[C@@H](N(C)C(=O)OC(C)(C)C)CC[C@H]2c1ccc(Cl)c(Cl)c1 -US06153768,2,COCOc1ccc(C2(C)COc3cc(OCOC)ccc3C2CCCCCCCCO)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COCOc1ccc(C2(C)COc3cc(OCOC)ccc3C2CCCCCCCCOS(=O)(=O)c2ccc(C)cc2)cc1 -US20090105305A1,2,CNC.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)c1cccc(C(=O)O)c1>>Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)c1cccc(C(=O)N(C)C)c1 -US20150018332A1,3,Ic1c[nH]cn1.OB(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(-c2c[nH]cn2)cc(C(F)(F)F)c1 -US05654299,2,N#CC1CCNCC1.O=C(Cl)OCc1ccccc1>>N#CC1CCN(C(=O)OCc2ccccc2)CC1 -US20120101079A1,1,CCSc1nc(Cl)cc(C)c1C(=O)NCc1cccc(F)c1.OC[C@H]1COCCN1>>CCSc1nc(N2CCOC[C@@H]2CO)cc(C)c1C(=O)NCc1cccc(F)c1 -US20120095249A1,3,C#CC1CC1.CC1(C)[C@@]2(C)CC[C@]1(C(=O)Nc1ccc(Cl)cc1C(=O)C(F)(F)F)OC2=O>>CC1(C)[C@@]2(C)CC[C@]1(C(=O)Nc1ccc(Cl)cc1[C@@](O)(C#CC1CC1)C(F)(F)F)OC2=O -US06492393B1,7,Cc1ccc(C(C)(C)C)cc1[N+](=O)[O-]>>Cc1ccc(C(C)(C)C)cc1N -US20140235623A1,2,CNc1cccc(N)c1C#N.O=C=NC(=O)c1ccccc1>>CNc1cccc(NC(=O)NC(=O)c2ccccc2)c1C#N -US20110207731A1,2,CC1=C(C#N)C(c2ccc3c(c2)c(N)nn3C(=O)OC(C)(C)C)C(C#N)=C(C)N1.O=S(=O)(Cl)Cc1ccc(F)cc1>>CC1=C(C#N)C(c2ccc3c(c2)c(NS(=O)(=O)Cc2ccc(F)cc2)nn3C(=O)OC(C)(C)C)C(C#N)=C(C)N1 -US20090054398A1,2,N[C@H]1C(=O)Nc2ccccc2S[C@H]1c1ccccc1.O=C(Cc1cc(F)cc(F)c1)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)O>>O=C(Cc1cc(F)cc(F)c1)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H]1C(=O)Nc2ccccc2S[C@@H]1c1ccccc1 -US20140309193A1,2,CCN.CCOC(=O)c1c(OCc2ccccc2)c(OCc2ccccc2)c(C(=O)N(C)C)n1-c1ccc(OC)cc1>>CCNC(=O)c1c(OCc2ccccc2)c(OCc2ccccc2)c(C(=O)N(C)C)n1-c1ccc(OC)cc1 -US20080221096A1,1,CN(Cc1ccccc1)c1nc2oc3c(Cl)ncnc3c2c2c1COC(C)(C)C2.NCCN1CCOCC1>>CN(Cc1ccccc1)c1nc2oc3c(NCCN4CCOCC4)ncnc3c2c2c1COC(C)(C)C2 -US07820704B2,3,Clc1nccc(NC2CCCC2)n1.OB(O)c1ccc(OCc2ccccc2)cc1>>c1ccc(COc2ccc(-c3nccc(NC4CCCC4)n3)cc2)cc1 -US20090221555A1,1,C#CCNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl.CCN1CC(O)(CO)COc2cc(N)ccc21>>C#CCNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)OCC(O)(CO)CN3CC)ncc1Cl -US08003677B2,2,NCCC1CC1.O=C(O)c1ccc(N2CC3=C(CN(C(=O)c4ccccc4C(F)(F)F)C3)C2)nc1>>O=C(NCCC1CC1)c1ccc(N2CC3=C(CN(C(=O)c4ccccc4C(F)(F)F)C3)C2)nc1 -US20130143892A1,2,CC(C)(C)c1noc(N2CCC(NC3CC3)CC2)n1.N#Cc1ccc(-c2cc(C(=O)O)on2)c(F)c1>>CC(C)(C)c1noc(N2CCC(N(C(=O)c3cc(-c4ccc(C#N)cc4F)no3)C3CC3)CC2)n1 -US20090123563A1,10,Cc1ccc(C(=O)O)cc1F.O=C1CCC(=O)N1Br>>O=C(O)c1ccc(CBr)c(F)c1 -US20090105305A1,6,COC(=O)CS(=O)(=O)Nc1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)ccc1C>>Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)CC(=O)O -US07910592B2,3,COc1ccc(B(O)O)cc1.O=S(=O)(OC1=CCC2(CC1)OCCO2)C(F)(F)F>>COc1ccc(C2=CCC3(CC2)OCCO3)cc1 -US20070066624A1,2,CC(C)(C)OC(=O)N1CCC(N2C(=O)NC[C@H]2c2ccccc2)CC1.CN=C=O>>CNC(=O)N1C[C@@H](c2ccccc2)N(C2CCN(C(=O)OC(C)(C)C)CC2)C1=O -US07598393B2,1,NCC1(O)CCCC1.O=[N+]([O-])c1cc(Br)ccc1Br>>O=[N+]([O-])c1cc(Br)ccc1NCC1(O)CCCC1 -US20020192594A1,2,C=CC(=O)Cl.OCC(Cl)(Cl)Cl>>C=CC(=O)OCC(Cl)(Cl)Cl -US06599922B2,2,NCC1CCCCN1.O=C(OCC(F)(F)F)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F>>O=C(NCC1CCCCN1)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F -US20150218170A1,1,Cc1nc2c(nc1Br)c(C(=O)NC(C)(C)C)cn2COCC[Si](C)(C)C.Cn1cc(N)cn1>>Cc1nc2c(nc1Nc1cnn(C)c1)c(C(=O)NC(C)(C)C)cn2COCC[Si](C)(C)C -US20150259351A1,1,C[C@@H]([NH3+])C1CCOCC1.Fc1ncccc1I>>C[C@@H](Nc1ncccc1I)C1CCOCC1 -US20120108574A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(Cl)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1.O=C(OCc1ccccc1)c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccc(C(=O)OCc5ccccc5)cc4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1 -US07897602B2,6,CCOC(=O)CCc1c(/C=C2\C(=O)Nc3ccccc32)[nH]c2c1C(=O)CCC2>>O=C(O)CCc1c(/C=C2\C(=O)Nc3ccccc32)[nH]c2c1C(=O)CCC2 -US20070060584A1,9,COC(=O)c1ncc(-c2cccc(-c3ccccc3C(F)(F)F)c2)[nH]1.N>>NC(=O)c1ncc(-c2cccc(-c3ccccc3C(F)(F)F)c2)[nH]1 -US06255315B1,7,C1=C(c2ccccn2)CCC2(C1)OCCO2>>c1ccc(C2CCC3(CC2)OCCO3)nc1 -US09067921B2,6,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1C1CCc2ccc(C(F)(F)F)cc21>>C[C@H]1CNCCN1C1CCc2ccc(C(F)(F)F)cc21 -US20140113898A1,1,BrCCBr.COC(=O)c1cc(C(F)(F)F)n[nH]1>>COC(=O)c1cc(C(F)(F)F)nn1CCBr -US06329405B1,7,CC(NC(c1ccc(F)cc1)c1cccc([N+](=O)[O-])c1)c1ccc(F)c(F)c1>>CC(NC(c1ccc(F)cc1)c1cccc(N)c1)c1ccc(F)c(F)c1 -US07410972B2,2,COc1nc(Cl)cnc1N.O=S(=O)(Cl)c1ccc(Br)s1>>COc1nc(Cl)cnc1NS(=O)(=O)c1ccc(Br)s1 -US05011992,1,CCC(=O)CBr.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1O>>CCC(=O)COc1cc(N)c(Cl)cc1C(=O)NCCN(CC)CC -US08791102B2,2,N[C@@H](COCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1.O=C(O)Cc1cnccn1>>O=C(Cc1cnccn1)N[C@@H](COCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 -US04233318,2,CCN=C=S.NCc1ccccc1>>CCNC(=S)NCc1ccccc1 -US08058441B2,1,C=CC(=O)Nc1ccc2c(c1)C(C)(c1ccccc1)CC(C)(C)N2C(C)=O.CCOCCO>>CCOCCOCCC(=O)Nc1ccc2c(c1)C(C)(c1ccccc1)CC(C)(C)N2C(C)=O -US20100120864A1,7,COC(=O)C(N)c1cccc(NC2CCCCC2)c1>>NC(CO)c1cccc(NC2CCCCC2)c1 -US20100204196A1,1,C=O.COc1ccc(N)c(C)c1>>CNc1ccc(OC)cc1C -US04665079,1,CCNCC1CCNC1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)nc21>>CCNCC1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3CC)C1 -US20100029655A1,1,CN1CCN(Cc2ccc(-c3cc(CCl)on3)cc2)CC1.Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F>>CN1CCN(Cc2ccc(-c3cc(Cn4cc5nc(-c6cccc(F)c6F)nc-5cn4)on3)cc2)CC1 -US20100197908A1,9,CCOC(=O)c1csc(N)n1.ICI>>CCOC(=O)c1csc(I)n1 -US20090093459A1,2,CC(C)(C)C(=O)ON[C@@H](CSc1c(N)cccc1-c1ccccc1)C(=O)O>>CC(C)(C)C(=O)ON[C@H]1CSc2c(cccc2-c2ccccc2)NC1=O -US20090118284A1,3,CC1(C)OB(c2cn[nH]c2)OC1(C)C.O=[N+]([O-])c1ccc2c(c1)c(Br)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>O=[N+]([O-])c1ccc2c(c1)c(-c1cn[nH]c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20130331561A1,6,CCCCCc1ccc(-c2cc3cn([C@H]4C[C@H](OC(=O)OCc5ccccc5)[C@@H](CO[Si](C)(C)C(C)(C)C)O4)c(=O)nc3o2)cc1>>CCCCCc1ccc(-c2cc3cn([C@H]4C[C@H](OC(=O)OCc5ccccc5)[C@@H](CO)O4)c(=O)nc3o2)cc1 -US20140088306A1,6,CN(C)c1ccc(-c2cnc3ccc(O[Si](C)(C)C(C)(C)C)cc3n2)cc1>>CN(C)c1ccc(-c2cnc3ccc(O)cc3n2)cc1 -US20070155805A1,6,COC(=O)c1sc2cc(C(F)(F)F)ccc2c1C>>Cc1c(C(=O)O)sc2cc(C(F)(F)F)ccc12 -US20140336106A1,6,COc1ccc([C@@H](O)[C@H](NC(=O)[C@H](CO)NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1>>COc1ccc([C@@H](O)[C@H](NC(=O)[C@@H](N)CO)C(=O)OCc2ccccc2)cc1 -US03987160,7,CCCOc1ccc(C)cc1-c1nc(N)c(N=O)c(=O)[nH]1>>CCCOc1ccc(C)cc1-c1nc(N)c(N)c(=O)[nH]1 -US20150099777A1,6,CCCc1nc2c(cc1C(=O)OC)C(=O)N(C1CCN(Cc3cc(C4CC4)c(-c4ccc(F)cc4F)c(F)c3OC)CC1)CC2>>CCCc1nc2c(cc1C(=O)O)C(=O)N(C1CCN(Cc3cc(C4CC4)c(-c4ccc(F)cc4F)c(F)c3OC)CC1)CC2 -US20130336921A1,2,Cc1ccc(-n2ccc(N)n2)cc1C.O=C(Cl)c1cc(Cl)ccc1[N+](=O)[O-]>>Cc1ccc(-n2ccc(NC(=O)c3cc(Cl)ccc3[N+](=O)[O-])n2)cc1C -US20090221555A1,1,COc1cc2c(cc1[N+](=O)[O-])CCNCC2.OC(CF)CF>>COc1cc2c(cc1[N+](=O)[O-])CCN(C(CF)CF)CC2 -US20070185117A1,3,C#CCNC(=O)OC(C)(C)C.CCOC(=O)c1cn2c3c(cc(Br)cc3c1=O)CCC2>>CCOC(=O)c1cn2c3c(cc(C#CCNC(=O)OC(C)(C)C)cc3c1=O)CCC2 -US08524917B2,1,BrCc1ccccc1.CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(O)cc2n1Cc1ccccc1>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OCc3ccccc3)cc2n1Cc1ccccc1 -US20110046134A1,6,CCOC(=O)CNC(=O)c1cccs1>>O=C(O)CNC(=O)c1cccs1 -US04146631,2,Nc1nnn[nH]1.O=C(O)c1cccc([N+](=O)[O-])c1O>>O=C(Nc1nnn[nH]1)c1cccc([N+](=O)[O-])c1O -US20040138223A1,2,CC(C)c1ccc(NCc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)cc1.O=C(O)C1CCCc2c(OCc3ccccc3)cccc21>>CC(C)c1ccc(N(Cc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cc1 -US07560463B2,6,CC(C)(C)OC(=O)NCCc1ccc(Oc2ncccc2C(N)=O)cc1>>NCCc1ccc(Oc2ncccc2C(N)=O)cc1 -US03976633,2,CC(=O)OC(C)=O.N#Cc1ccc(C(F)(F)F)cc1N=NNc1cc(C(F)(F)F)ccc1C#N>>CC(=O)N(N=Nc1cc(C(F)(F)F)ccc1C#N)c1cc(C(F)(F)F)ccc1C#N -US20100029710A1,7,CCc1nc2c(C)cc(CC(C)=O)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21>>CCc1nc2c(C)cc(CC(C)O)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21 -US20090306108A1,6,C=CCNc1nc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1cc(C(=O)OC)ccc1C>>C=CCNc1nc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1cc(C(=O)O)ccc1C -US20110136800A1,6,COC(=O)c1ccc2c(c1)C[C@H]1[C@@H]2CCCN1C(=O)c1ccc2[nH]cnc2c1>>O=C(O)c1ccc2c(c1)C[C@H]1[C@@H]2CCCN1C(=O)c1ccc2[nH]cnc2c1 -US04948810,1,ClCc1ccccc1.O=Cc1cc(F)c(O)c(F)c1>>O=Cc1cc(F)c(OCc2ccccc2)c(F)c1 -US04670581,2,CC(=O)Cl.Oc1ccc(-c2ccccc2)cc1>>CC(=O)Oc1ccc(-c2ccccc2)cc1 -US20110195964A1,6,CC(C)(C)OC(=O)CSc1nc2cc(-c3ccc(-c4ccccc4O)cc3)c(Cl)cc2[nH]1>>O=C(O)CSc1nc2cc(-c3ccc(-c4ccccc4O)cc3)c(Cl)cc2[nH]1 -US09040528B2,6,C[C@@H]1O[C@H](C)CN2c3c(cc4c(N5CCN(C(=O)OC(C)(C)C)CC5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)[C@@H]12>>C[C@@H]1O[C@H](C)CN2c3c(cc4c(N5CCNCC5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)[C@@H]12 -US20110118230A1,1,COC(=O)c1c(CBr)n(S(=O)(=O)c2ccccc2)c2ncccc12.Cc1ccc(S(=O)(=O)NCC#N)cc1>>COC(=O)c1c(CN(CC#N)S(=O)(=O)c2ccc(C)cc2)n(S(=O)(=O)c2ccccc2)c2ncccc12 -US04251261,2,CC(C)O.O=C(O)c1sc(Cl)nc1C(F)(F)F>>CC(C)OC(=O)c1sc(Cl)nc1C(F)(F)F -US08067407B2,1,FC1(F)CCNC1.O=c1c(-n2ccnc2)c[nH]n1-c1cc(Cl)ncn1>>O=c1c(-n2ccnc2)c[nH]n1-c1cc(N2CCC(F)(F)C2)ncn1 -US20110105470A1,1,BrCC1CCCO1.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccccc2C2=C1SCC1(CCN(CC3CCCO3)CC1)O2 -US20120238547A1,1,Cc1cc(Cl)nc(Cl)c1[N+](=O)[O-].F[C@@H]1CCNC1>>Cc1cc(Cl)nc(N2CC[C@@H](F)C2)c1[N+](=O)[O-] -US20130059853A1,1,COc1c(OC(F)F)ccc(-c2cccc3c2CCC3=O)c1O.CS(=O)(=O)c1ccc(CBr)cc1>>COc1c(OC(F)F)ccc(-c2cccc3c2CCC3=O)c1OCc1ccc(S(C)(=O)=O)cc1 -US20150045351A1,3,CI.CN1CC2CN(C(=O)OC(C)(C)C)CCc3c(Br)cc(Br)c1c32>>Cc1cc(Br)c2c3c1N(C)CC3CN(C(=O)OC(C)(C)C)CC2 -US08778926B2,1,CCc1cnc(Cl)nc1.CS(=O)(=O)N1CC=C(c2cc3c(cn2)O[C@@H](C2CCNCC2)C3)CC1>>CCc1cnc(N2CCC([C@H]3Cc4cc(C5=CCN(S(C)(=O)=O)CC5)ncc4O3)CC2)nc1 -US06114334,3,C=O.COc1ccccc1N1CCNCC1.Nc1cc(C2CC2)nn1-c1ccccc1>>COc1ccccc1N1CCN(Cc2c(C3CC3)nn(-c3ccccc3)c2N)CC1 -US20040082583A1,1,CC(=O)Nc1ccc(O)cc1.O=[N+]([O-])c1ccc(Br)cn1>>CC(=O)Nc1ccc(Oc2ccc([N+](=O)[O-])nc2)cc1 -US20120295900A1,1,COc1ccc(C(NC2=N[C@](C)(c3cc(Br)ccc3F)[C@@H](F)CO2)(c2ccccc2)c2ccc(OC)cc2)cc1.COc1ccccc1N>>COc1ccc(C(NC2=N[C@](C)(c3cc(Nc4ccccc4OC)ccc3F)[C@@H](F)CO2)(c2ccccc2)c2ccc(OC)cc2)cc1 -US04992432,6,COc1ccc([C@H]2SC=C(c3ccccc3)N(CCN(C)C)C(=O)[C@H]2OC(C)=O)cc1>>COc1ccc([C@H]2SC=C(c3ccccc3)N(CCN(C)C)C(=O)[C@H]2O)cc1 -US04851526,1,CCCCN1CCCC(=O)C1.Cc1cc(-n2ccnc2)ccc1N>>CCCCN1CCCC(Nc2ccc(-n3ccnc3)cc2C)C1 -US20100256092A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)CC1OB(O)c2cc(Oc3cccc(C=O)c3)ccc21>>CCOC(=O)CC1OB(O)c2cc(Oc3cccc(CN4CCN(C(=O)OC(C)(C)C)CC4)c3)ccc21 -US06307056B1,3,COc1ccc(B(O)O)c(OC)c1.Cc1nc[nH]c1/C=C1\C(=O)Nc2ccc(F)c(I)c21>>COc1ccc(-c2c(F)ccc3c2/C(=C/c2[nH]cnc2C)C(=O)N3)c(OC)c1 -US20150175604A1,1,BrCc1ccccn1.Cc1cc2c(ccc3nnc(C)n32)[nH]1>>Cc1cc2c(ccc3nnc(C)n32)n1Cc1ccccn1 -US20080051405A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]1CO.CC(C)(C)[Si](C)(C)OCc1cccc(Br)n1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cccc(CO[Si](C)(C)C(C)(C)C)n1 -US20050256132A1,2,C1CN(CCN2CCOCC2)CCN1.COc1ccccc1[C@H](c1cccc2ccccc12)[C@@](C)(C#N)C(=O)O>>COc1ccccc1[C@H](c1cccc2ccccc12)[C@@](C)(C#N)C(=O)N1CCN(CCN2CCOCC2)CC1 -US20070232607A1,1,C[C@H](O)C(=O)N(C)C.Cc1ccc(Oc2ccc(Nc3ncnc4cccc(F)c34)cc2C)cn1>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@@H](C)C(=O)N(C)C)c34)cc2C)cn1 -US05110956,3,CC(C)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc2c(c1)OCO2>>CC(C)=Cc1ccc2c(c1)OCO2 -US20110003852A1,1,CC(C)(C)OC(=O)N1CCC(CCO)CC1.O=C(OCc1ccccc1)c1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(CCOc2ccc(C(=O)OCc3ccccc3)cc2)CC1 -US20110166163A1,1,CCc1ccc(-c2coc3ncnc(Cl)c23)cc1.C[C@@H](O)CCCCC(=O)OC(C)(C)C>>CCc1ccc(-c2coc3ncnc(O[C@H](C)CCCCC(=O)OC(C)(C)C)c23)cc1 -US08946260B2,1,Fc1cncc(Br)c1.O=c1[nH]ccc2ccc(C(F)(F)F)cc12>>O=c1c2cc(C(F)(F)F)ccc2ccn1-c1cncc(F)c1 -US20080312255A1,4,CCOC(=O)c1sc(Cl)nc1C(=O)NNC=O>>CCOC(=O)c1sc(Cl)nc1-c1nnco1 -US20090227603A1,3,CCCS(=O)(=O)c1cc(Br)cc(OCCCCCCc2cccc(OCCCC(=O)OCC)c2CCC(=O)OCC)c1.OB(O)c1ccsc1>>CCCS(=O)(=O)c1cc(OCCCCCCc2cccc(OCCCC(=O)OCC)c2CCC(=O)OCC)cc(-c2ccsc2)c1 -US08455521B2,2,N[C@@H]1CN(C(=O)OCc2ccccc2)CC[C@H]1C1CCCCC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(N[C@@H]1CN(C(=O)OCc2ccccc2)CC[C@H]1C1CCCCC1)Oc1ccc([N+](=O)[O-])cc1 -US20110201577A1,2,CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@@H](NC(C)=O)[C@H](N=[N+]=[N-])[C@@H]1O.CS(=O)(=O)Cl>>CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@@H](NC(C)=O)[C@H](N=[N+]=[N-])[C@@H]1OS(C)(=O)=O -US08916599B2,1,CN.O=C(Nc1ccc(Br)cc1)c1ccc(F)c([N+](=O)[O-])c1>>CNc1ccc(C(=O)Nc2ccc(Br)cc2)cc1[N+](=O)[O-] -US20040236109A1,3,CC(=O)N1c2ccc(NC(=O)c3cccc(C)c3Br)cc2C(C)(c2ccccc2)CC1(C)C.OB(O)c1ccccc1>>CC(=O)N1c2ccc(NC(=O)c3cccc(C)c3-c3ccccc3)cc2C(C)(c2ccccc2)CC1(C)C -US06566377B2,6,O=C(NCCOc1ccc(-c2cnoc2)cc1)OCc1ccccc1>>NCCOc1ccc(-c2cnoc2)cc1 -US20100160304A1,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.O=[N+]([O-])c1cccnc1Cl>>C=C(OCC)c1ncccc1[N+](=O)[O-] -US06927228B2,2,CNCc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1.O=C(O)c1ccno1>>CN(Cc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1)C(=O)c1ccno1 -US05622951,9,COc1ccccc1N1CCN(C2CCC(O)(c3ccc(C)cc3C)CC2)CC1>>COc1ccccc1N1CCN([C@@H]2CC[C@@H](c3ccc(C)cc3C)CC2)CC1 -US06962935B2,4,CCOC(=O)C(Br)C(=O)c1cccc(C#N)c1.NC(N)=S>>CCOC(=O)c1sc(N)nc1-c1cccc(C#N)c1 -US20040259843A1,1,C#C[C@H]1CC[C@@H](C#N)N1C(=O)CCl.NC1CCCC1>>C#C[C@H]1CC[C@@H](C#N)N1C(=O)CNC1CCCC1 -US05792769,1,CC(C)(C)OC(=O)N1CCC(CO)CC1.Cc1cc(O)cc(OS(=O)(=O)c2ccccc2)c1>>Cc1cc(OCC2CCN(C(=O)OC(C)(C)C)CC2)cc(OS(=O)(=O)c2ccccc2)c1 -US20100216802A1,1,CC(C)(C)OC(=O)N[C@@H](CCO[Si](C)(C)C(C)(C)C)C(=O)O.CC1CCC(C(C)C)C(O)C1>>CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@H](CCO[Si](C)(C)C(C)(C)C)NC(=O)OC(C)(C)C -US06818774B2,7,COC(=O)Cc1cc(OCc2ccc(F)cc2)ccc1C(=O)O>>COC(=O)Cc1cc(OCc2ccc(F)cc2)ccc1CO -US04414226,6,COc1cc(C)cc2c(=O)oc3c(c12)C(=O)c1cccc(O)c1C3=O>>Cc1cc(O)c2c3c(oc(=O)c2c1)C(=O)c1c(O)cccc1C3=O -US05010077,7,CCOC(=O)c1ncc2[nH]c3ccc([N+](=O)[O-])cc3c2c1C>>CCOC(=O)c1ncc2[nH]c3ccc(N)cc3c2c1C -US04435419,2,Clc1ccc(C23CNCC2C3)cc1.O=C(Cl)c1cccc(F)c1>>O=C(c1cccc(F)c1)N1CC2CC2(c2ccc(Cl)cc2)C1 -US20040024210A1,1,CC(C)(C)OC(=O)N1CCN(c2nccc3ccc(Br)cc23)CC1.CC(C)(C)c1ccccc1S>>CC(C)(C)OC(=O)N1CCN(c2nccc3ccc(Sc4ccccc4C(C)(C)C)cc23)CC1 -US20060135782A1,1,COc1cc2ncnc(Cl)c2cc1OC.Nc1nc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2s1>>COc1cc2ncnc(Nc3nc4ccc(NC(=O)Nc5ccc(Cl)c(C(F)(F)F)c5)cc4s3)c2cc1OC -US08034812B2,2,Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1.O=C(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US06426345B1,6,CC(=O)Nc1cccc(-n2c(=O)c(C)nc3cccnc32)c1>>Cc1nc2cccnc2n(-c2cccc(N)c2)c1=O -US06117869,2,N[C@@H](CCc1ccccc1)C(=O)O.O=S(=O)(Cl)c1ccc2c(c1)Sc1ccccc1O2>>O=C(O)[C@H](CCc1ccccc1)NS(=O)(=O)c1ccc2c(c1)Sc1ccccc1O2 -US04902694,3,Brc1csc2ccncc12.CN(C)C=O>>O=Cc1csc2ccncc12 -US20110052612A1,1,ClCc1ccc(Cl)cc1.O=C1CCNCC1>>O=C1CCN(Cc2ccc(Cl)cc2)CC1 -US20090093454A1,1,C1COCCN1.Fc1cccc2nc(CN3CCC[C@@H]4CCc5cccnc5[C@@H]43)cn12>>c1cnc2c(c1)CC[C@H]1CCCN(Cc3cn4c(N5CCOCC5)cccc4n3)[C@@H]21 -US05051422,1,COc1ccc(CN2CCN(c3cc(Cl)cc(Cl)c3)CC2CO)cc1OC.O=[N+]([O-])c1ccc(CCl)cc1>>COc1ccc(CN2CCN(c3cc(Cl)cc(Cl)c3)CC2COCc2ccc([N+](=O)[O-])cc2)cc1OC -US20070027163A1,1,NCCCl.O=C(c1c[nH]c2cc(Cl)ccc12)N1CCC(c2cccc3c2OCC3)CC1>>NCCn1cc(C(=O)N2CCC(c3cccc4c3OCC4)CC2)c2ccc(Cl)cc21 -US20060004017A1,7,Oc1ccc2[nH]ccc2c1>>Oc1ccc2c(c1)CCN2 -US04275160,7,CCOC(=O)CCCC1C(=O)c2ccccc2N(CCCN(C)C)c2ccccc21>>CCOC(=O)CCCC1Cc2ccccc2N(CCCN(C)C)c2ccccc21 -US05593993,2,COC(=O)C(Cc1ccccc1)NC(=S)Nc1nc(C#N)cs1>>N#Cc1csc(N2C(=O)C(Cc3ccccc3)NC2=S)n1 -US20050026836A1,2,CC(C)(C)O.O=C(Cl)c1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)c1ccccc1[N+](=O)[O-] -US20080103174A1,2,NC1CCC(CCN2CCC(Oc3ccc(F)cc3F)CC2)CC1.O=C(O)c1ccnc2ccccc12>>O=C(N[C@@H]1CC[C@@H](CCN2CCC(Oc3ccc(F)cc3F)CC2)CC1)c1ccnc2ccccc12 -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(OCCC(=O)OC(C)(C)C)cc(C)c21>>Cc1cc(OCCC(=O)OC(C)(C)C)cc2c1C(CC(=O)O)OB2O -US20030060467A1,1,Cc1nnc(-c2ccccc2F)n2nc(O)c(Br)c12.Cn1ncnc1CCl>>Cc1nnc(-c2ccccc2F)n2nc(OCc3ncnn3C)c(Br)c12 -US03966931,2,CCN1CCN(C(=O)Cl)CC1.O=C1C2=C(SCCS2)C(O)N1c1ccc(Cl)cn1>>CCN1CCN(C(=O)OC2C3=C(SCCS3)C(=O)N2c2ccc(Cl)cn2)CC1 -US20100035865A1,2,CCS(=O)(=O)Cl.N[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1>>CCS(=O)(=O)N[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1 -US20130136719A1,1,COC(=O)c1sc(C#CC(C)(C)C)cc1NC(=O)c1ccc(Cl)cc1Cl.COCCBr>>COCCN(C(=O)c1ccc(Cl)cc1Cl)c1cc(C#CC(C)(C)C)sc1C(=O)OC -US20140200206A1,1,COc1cc(C(=O)NC2COC2)ccc1N.Cc1nc2ccc(-c3cn(COCC[Si](C)(C)C)c4nc(Cl)nc(OC5(C)CCC5)c34)cc2o1>>COc1cc(C(=O)NC2COC2)ccc1Nc1nc(OC2(C)CCC2)c2c(-c3ccc4nc(C)oc4c3)cn(COCC[Si](C)(C)C)c2n1 -US05936000,9,C#CCC(CC#C)(C(=O)OC)C(=O)OC>>C#CCC(CC#C)C(=O)OC -US20120101134A1,6,CCOC(=O)CCCOc1cccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c1CC>>CCc1c(OCCCC(=O)O)cccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 -US08846661B2,3,Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1.COc1ccccc1B(O)O>>COc1ccccc1-c1cncc(N2CC3CC4CC2CN(C4)C3)c1 -US20150284408A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.CN(C)c1ccc(C=O)cc1[N+](=O)[O-]>>CN(C)c1ccc(CNC2CCN(C(=O)OC(C)(C)C)CC2)cc1[N+](=O)[O-] -US05922724,1,Nc1cccc(-c2ccccn2)c1.O=[N+]([O-])c1cc(I)ccc1F>>O=[N+]([O-])c1cc(I)ccc1Nc1cccc(-c2ccccn2)c1 -US04006144,1,FC(F)(F)c1ccc2c(c1)CC(Cl)c1ccccc1S2.O=C1OCCN1CCN1CCNCC1>>O=C1OCCN1CCN1CCN(C2Cc3cc(C(F)(F)F)ccc3Sc3ccccc32)CC1 -US06949546B2,6,CC(C)(C)OC(=O)N1CC[C@@H](NC(=O)OCc2ccccc2)[C@@H](C(=O)N2CCC[C@@H](Cc3ccc(F)cc3)C2)C1>>CC(C)(C)OC(=O)N1CC[C@@H](N)[C@@H](C(=O)N2CCC[C@@H](Cc3ccc(F)cc3)C2)C1 -US20150051195A1,3,CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1.OB(O)c1cccc2ncccc12>>CCCC(C(=O)OC)c1c(C)nc(-c2cccc3ncccc23)nc1-c1ccc(C)cc1 -US20090042862A1,1,N#Cc1ccc(F)cc1C(F)(F)F.OCCCN1CCCCC1>>N#Cc1ccc(OCCCN2CCCCC2)cc1C(F)(F)F -US20080096861A1,1,CC(C)CC=O.c1cnc2c(c1)CCCC2NCc1nc2ccccc2[nH]1>>CC(C)CCN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21 -US20110218103A1,4,NC(=O)c1cccc(N)c1N.O=C(O)C(F)(F)Cl>>NC(=O)c1cccc2[nH]c(C(F)(F)Cl)nc12 -US20020065308A1,1,CC(C)(C)[Si](C)(C)OC(CCC1CCC(=O)N1)Cc1cccc(Oc2ccccc2)c1.COC(=O)c1ccc(CCCBr)cc1>>COC(=O)c1ccc(CCCN2C(=O)CCC2CCC(Cc2cccc(Oc3ccccc3)c2)O[Si](C)(C)C(C)(C)C)cc1 -US20050148621A1,2,NCCCCCNc1c2c(nc3ccccc13)CCCC2.O=C(O)CCc1c[nH]c2ccccc12>>O=C(CCc1c[nH]c2ccccc12)NCCCCCNc1c2c(nc3ccccc13)CCCC2 -US20100305140A1,2,CC(C)(C)c1nc2cc(C(=O)O)ccc2n1CC1CCC(F)(F)CC1.COC(=O)CC1CCNCC1>>COC(=O)CC1CCN(C(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCC(F)(F)CC2)CC1 -US07582761B2,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1cncnc1Cl>>CC(C)(C)OC(=O)N1CCN(c2ncncc2Cl)CC1 -US05130485,1,C#CCBr.O=C(O)c1ccccc1S>>C#CCSc1ccccc1C(=O)O -US20150232481A1,1,C=CC[C@@H](C)O.O=Cc1cc(F)c(F)cc1O>>C=CC[C@H](C)Oc1cc(F)c(F)cc1C=O -US20100222326A1,6,CC[C@@H](C(N)=O)N1CN(Cc2ccccc2)CC1=O>>CC[C@@H](C(N)=O)N1CNCC1=O -US20060052348A1,6,COc1ccc2cc(-c3cnc(-c4ccccc4)o3)ccc2c1>>Oc1ccc2cc(-c3cnc(-c4ccccc4)o3)ccc2c1 -US20030144319A1,6,CC(C)(C)OC(=O)Nc1ccc(CCN2CCCC(Cc3ccccc3)C2)cc1>>Nc1ccc(CCN2CCCC(Cc3ccccc3)C2)cc1 -US20100184799A1,6,CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccc(F)cc2)c[nH]1>>N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccc(F)cc2)c[nH]1 -US20120034270A1,1,CC(C)(C)OC(=O)NC1(COS(C)(=O)=O)COC(C)(C)OC1.COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c[nH]c2c1>>COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(CC3(NC(=O)OC(C)(C)C)COC(C)(C)OC3)c2c1 -US20090076147A1,1,CC(=O)NCCCS(=O)(=O)OCC(C)(C)[C@@H](O[Si](C)(C)C(C)(C)C)C(=O)O.Cc1oc(=O)oc1CBr>>CC(=O)NCCCS(=O)(=O)OCC(C)(C)[C@@H](O[Si](C)(C)C(C)(C)C)C(=O)OCc1oc(=O)oc1C -US20110152318A1,1,CC(NC(=O)c1coc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1.CCc1cccc(O)c1>>CCc1cccc(Oc2nc(C(=O)NC(C)c3cc(F)c(NS(C)(=O)=O)c(F)c3)co2)c1 -US03946008,1,COc1cc(OC)c2c3c(c(=O)oc2c1)CNCC3.ClCCN1CCCCC1>>COc1cc(OC)c2c3c(c(=O)oc2c1)CN(CCN1CCCCC1)CC3 -US20040224976A1,2,CCOC(OCC)c1cc2ccc(C(=O)O)cc2o1.N[C@H]1CN2CCC1CC2>>CCOC(OCC)c1cc2ccc(C(=O)N[C@H]3CN4CCC3CC4)cc2o1 -US20140011971A1,1,Cc1ccccc1C(N)c1ccccc1C.O=Cc1ccccn1>>Cc1ccccc1C(/N=C/c1ccccn1)c1ccccc1C -US08143271B2,1,Brc1c[nH]c2ncccc12.Nc1ccccc1>>c1ccc(Nc2c[nH]c3ncccc23)cc1 -US20080306120A1,2,COc1ccc(Cn2cc(-c3ccnc4[nH]ccc34)c(-c3ccc(N)cc3)n2)cc1.O=C=Nc1ccccc1>>COc1ccc(Cn2cc(-c3ccnc4[nH]ccc34)c(-c3ccc(NC(=O)Nc4ccccc4)cc3)n2)cc1 -US20140135318A1,3,CCCCN(CCCC)C(=O)c1ncn(C)c1Br.COC(=O)c1ccc(B2OCC(C)(C)CO2)c(C(=O)N2CCc3ccccc3C2)c1>>CCCCN(CCCC)C(=O)c1ncn(C)c1-c1ccc(C(=O)OC)cc1C(=O)N1CCc2ccccc2C1 -US06476040B1,1,CCc1cccc(N)c1.COCCOc1cc2ncnc(Cl)c2cc1OCCOC>>CCc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 -US05037990,2,Nc1nnn[nH]1.O=C(O)COc1cccc(CCNC(=O)OCc2ccccc2)c1>>O=C(COc1cccc(CCNC(=O)OCc2ccccc2)c1)Nc1nnn[nH]1 -US20080015203A1,1,CS(=O)(=O)c1cc(F)c(F)cc1F.C[C@@H](CO)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1>>C[C@@H](CO)Oc1cc(Oc2cc(F)c(S(C)(=O)=O)cc2F)cc(C(=O)Nc2ccn(C)n2)c1 -US05109002,3,O=C(CC1CCN(CC2CC2)CC1)c1ccc(F)cc1.[Mg+]c1ccccc1>>OC(CC1CCN(CC2CC2)CC1)(c1ccccc1)c1ccc(F)cc1 -US20040192685A1,7,COc1ccc2c(c1)CCN=C2c1ccc(OCc2ccccc2)cc1>>COc1ccc2c(c1)CCNC2c1ccc(OCc2ccccc2)cc1 -US20040092737A1,6,COCN1c2cc(CN3C(=O)c4ccccc4C3=O)ccc2Sc2nccnc21>>COCN1c2cc(CN)ccc2Sc2nccnc21 -US20070232615A1,6,CN(Cc1cn2c(N3CC[C@@H](NC(=O)OC(C)(C)C)C3)cccc2n1)[C@H]1CCCc2cccnc21>>CN(Cc1cn2c(N3CC[C@@H](N)C3)cccc2n1)[C@H]1CCCc2cccnc21 -US08304539B2,2,CCOC(=O)c1nnc(N)s1.NC1CC1>>Nc1nnc(C(=O)NC2CC2)s1 -US07790756B2,2,C=C(C)OC(=O)Cl.CC(C)(C)c1cc(N)n(-c2ccc3ncccc3c2)n1>>C=C(C)OC(=O)Nc1cc(C(C)(C)C)nn1-c1ccc2ncccc2c1 -US05457106,3,O=C1CSC(=O)N1.O=Cc1cccs1>>O=C1NC(=O)C(=Cc2cccs2)S1 -US20060069110A1,1,CC(C)=O.CN(c1ccnc(N[C@@H](CN)Cc2ccccc2)n1)c1ccnc(-c2ccccc2)n1>>CC(C)NC[C@@H](Cc1ccccc1)Nc1nccc(N(C)c2ccnc(-c3ccccc3)n2)n1 -US20060161001A1,2,CC(=O)O.c1ccc(-c2ncc3c(n2)N(c2ccnc(NC4CCNCC4)n2)CCO3)cc1>>CC(=O)N1CCC(Nc2nccc(N3CCOc4cnc(-c5ccccc5)nc43)n2)CC1 -US06225324B1,1,C1CC2(CCN1)OCCO2.COc1ccc(C#N)cc1Br>>COc1ccc(C#N)cc1N1CCC2(CC1)OCCO2 -US04826990,1,ClCc1csc(-c2ccccc2)n1.O=[N+]([O-])c1ccccc1O>>O=[N+]([O-])c1ccccc1OCc1csc(-c2ccccc2)n1 -US07368578B2,1,COC(=O)c1cc(-c2nc(COc3ccc(CCl)cc3OC)c(C)o2)ccc1C.O=Cc1cn(-c2ccccc2)nc1O>>COC(=O)c1cc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4C=O)cc3OC)c(C)o2)ccc1C -US20050043368A1,6,CC1(C)CN(Cc2ccccc2)C[C@H]1O>>CC1(C)CNC[C@H]1O -US04352748,7,O=C1CCc2ccccc21>>OC1CCc2ccccc21 -US08846664B2,2,C1CN[C@@H](CN2CCCC2)C1.CC1(C)OB(c2ccc(C(=O)O)cc2)OC1(C)C>>CC1(C)OB(c2ccc(C(=O)N3CCC[C@@H]3CN3CCCC3)cc2)OC1(C)C -US08476430B2,6,COC(=O)c1ccc2c(c1)OCC2(C)C>>CC1(C)COc2cc(C(=O)O)ccc21 -US20100144694A1,1,CC(C)(Br)C(=O)Br.O=[N+]([O-])c1ccccc1NNC1C2CC3CC(C2)CC1C3>>CC(C)(Br)C(=O)N(Nc1ccccc1[N+](=O)[O-])C1C2CC3CC(C2)CC1C3 -US20080188426A1,2,CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3nccc(CCc4ccc(OCCCO)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3nccc(CCc4ccc(OCCCOS(C)(=O)=O)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C -US20080139558A1,2,O=C(O)c1cccnc1.O=c1cc(CNc2cccc(Cl)c2)c2cccc(F)c2[nH]1>>O=C(c1cccnc1)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1 -US20150274720A1,2,N=C(N)c1ccnc2[nH]c3ncc(F)cc3c12.O=C(O)c1c(F)cncc1C1CCC1>>N=C(NC(=O)c1c(F)cncc1C1CCC1)c1ccnc2[nH]c3ncc(F)cc3c12 -US08278282B2,8,O=C(OC[C@H]1O[C@H](OC(=O)c2ccccc2)[C@H](O)[C@@H]1OC(=O)c1ccccc1)c1ccccc1>>O=C(OC[C@H]1O[C@H](OC(=O)c2ccccc2)C(=O)[C@@H]1OC(=O)c1ccccc1)c1ccccc1 -US20130296312A1,1,CNS(C)(=O)=O.N#Cc1ccccc1CBr>>CN(Cc1ccccc1C#N)S(C)(=O)=O -US20140058098A1,6,NC(=O)[C@@H]1CN(C(=O)OCc2ccccc2)CCN1c1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2>>NC(=O)[C@@H]1CNCCN1c1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2 -US20150252072A1,6,CC(C)[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N1c2ncccc2C[C@H]1CNC(=O)c1ccccc1>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ncccc2C[C@H]1CNC(=O)c1ccccc1)C(C)C -US20070219187A1,6,CC(C)(C)OC(=O)NNC(=O)C1CCCN(C(=O)c2ccc(F)cc2)C1>>NNC(=O)C1CCCN(C(=O)c2ccc(F)cc2)C1 -US04102888,10,C=CCC(COc1ccc(F)cc1)OCc1ccccc1.O>>OCCCC(COc1ccc(F)cc1)OCc1ccccc1 -US07153863B2,8,CSc1nccc(-c2c(CC(C)C)nn3ccccc23)n1.O=C(OO)c1cccc(Cl)c1>>CC(C)Cc1nn2ccccc2c1-c1ccnc(S(C)=O)n1 -US05539112,6,Nc1c(F)cc(F)c2oc(-c3ccc(NCCCN4C(=O)c5ccccc5C4=O)c(F)c3)cc(=O)c12>>NCCCNc1ccc(-c2cc(=O)c3c(N)c(F)cc(F)c3o2)cc1F -US05866717,6,COCCOCCNC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)(C)C>>COCCOCCNC(=O)[C@@H](N)C(C)(C)C -US05107013,9,COc1ccc2cc(C(C)C#N)ccc2c1Br>>COc1ccc2cc(C(C)C#N)ccc2c1 -US09079853B2,3,CC(=O)c1ccccn1.CC(C)CN1C(=O)C(=O)c2cc(Cl)ccc21>>CC(C)CN1C(=O)C(O)(CC(=O)c2ccccn2)c2cc(Cl)ccc21 -US20140315886A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(O)cc1C(=O)O>>CC(C)(C)OC(=O)Nc1ccc(O)cc1C(=O)O -US20110212940A1,3,Brc1ccc2oc(Cc3ccccc3)cc2c1.O=Cc1ccc(B(O)O)c(F)c1>>O=Cc1ccc(-c2ccc3oc(Cc4ccccc4)cc3c2)c(F)c1 -US20110039823A1,4,C=CCC1(O)CCN(C(=O)OC(C)(C)C)CC1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CCC(O)(CC2CO2)CC1 -US04655816,1,CCOC(=O)c1c(Cl)cc(C(F)(F)F)nc1C(F)(F)F.O=[N+]([O-])c1ccc(O)cc1>>CCOC(=O)c1c(Oc2ccc([N+](=O)[O-])cc2)cc(C(F)(F)F)nc1C(F)(F)F -US20050143452A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1ccc(F)cc1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4ccc(F)cc4)c3O2)cc1 -US20130109661A1,2,COC(=O)c1ccc(C(=O)O)cc1.COc1ccc(Nc2cc(N3CCCC(N)C3)nn3ccnc23)nc1OC>>COC(=O)c1ccc(C(=O)NC2CCCN(c3cc(Nc4ccc(OC)c(OC)n4)c4nccn4n3)C2)cc1 -US20120289500A1,1,O=c1[nH]nc(Cl)c2ccccc12.Sc1ccncc1>>O=c1[nH]nc(Sc2ccncc2)c2ccccc12 -US07592456B2,1,O=S([O-])c1ccc2cc(-c3ccc(F)cc3)ccc2c1.OCc1ccsc1Br>>O=S(=O)(c1ccc2cc(-c3ccc(F)cc3)ccc2c1)c1sccc1CO -US20090227560A1,8,O=C(OCc1ccccc1)N1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)[C@H](CO)C1>>O=C[C@@H]1CN(C(=O)OCc2ccccc2)CCN1C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20120065199A1,10,Cc1oc(=O)oc1C.O=C1CCC(=O)N1Br>>Cc1oc(=O)oc1CBr -US20040132727A1,2,CCCC(C)C(=O)N=C=S.COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC>>CCCC(C)C(=O)NC(=S)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2ccncc2)c1.COc1ccc(NC(=O)OC(C)(C)C)c(N)c1>>COc1ccc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccncc3)c2)c1 -US05585368,8,CC(C)(O)CCCOCCC1CC2C(O)CCCC2(C)C1(C)C>>CC(C)(O)CCCOCCC1CC2C(=O)CCCC2(C)C1(C)C -US20110207704A1,1,CC(C)(C)OC(=O)CBr.Cc1c(-c2nc(-c3ccc(OC(C)C)c(Cl)c3)no2)nc2n1CCNC2>>Cc1c(-c2nc(-c3ccc(OC(C)C)c(Cl)c3)no2)nc2n1CCN(CC(=O)OC(C)(C)C)C2 -US20070254881A1,6,CCOC(=O)c1cc(-c2ccn(CC)c2)n(-c2ccc(C)nc2)n1>>CCn1ccc(-c2cc(C(=O)O)nn2-c2ccc(C)nc2)c1 -US20140378459A1,1,CC(C)(C)OC(=O)CBr.CC(C)(C)OC(=O)c1cccc(CCN)c1>>CC(C)(C)OC(=O)CNCCc1cccc(C(=O)OC(C)(C)C)c1 -US06333330B1,1,CCCC[SnH](CCCC)CCCC.CCc1ccc(Br)cn1>>CCCC[Sn](CCCC)(CCCC)c1ccc(CC)nc1 -US06809108B1,1,O=C(CCNC(=O)OCc1ccccc1)NC[C@H]1CCCNC1.O=CC1CCCCC1>>O=C(CCNC(=O)OCc1ccccc1)NC[C@H]1CCCN(CC2CCCCC2)C1 -US20140005213A1,4,CC(C)(C)OC(=O)N(CCF)[C@H]1CCN([C@H](c2ccc(NN)nc2)C(F)(F)F)C1.COc1cccc2ccc(C=O)nc12>>COc1cccc2ccc(-c3nnc4ccc([C@@H](N5CC[C@H](N(CCF)C(=O)OC(C)(C)C)C5)C(F)(F)F)cn34)nc12 -US20140288123A1,6,COC(=O)c1ccc(CN2CCCCC2)cc1C>>Cc1cc(CN2CCCCC2)ccc1C(=O)O -US04113869,1,C=O.COc1ccc2c(c1)CNCC2c1ccccc1>>COc1ccc2c(c1)CN(C)CC2c1ccccc1 -US07960435B2,2,Cc1ccc(N)c(C(=O)O)c1.O=S(=O)(Cl)c1ccc(F)cc1>>Cc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(=O)O)c1 -US20150274661A1,2,CCOC(=O)c1cc2cc(C3CCCN(C(C)C)C3)ccc2[nH]1.Nc1cc(F)cc(F)c1>>CC(C)N1CCCC(c2ccc3[nH]c(C(=O)Nc4cc(F)cc(F)c4)cc3c2)C1 -US06890935B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC[C@@H]1CCCN1>>CC(C)(C)OC(=O)N1CCC[C@H]1CO -US20110046130A1,6,CC(C)(C)OC(=O)NC1CCN(C2CCC2)CC1>>NC1CCN(C2CCC2)CC1 -US06469039B1,6,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CCc1ccc(C(=N)N)cc1)n2C)c1ccccn1>>Cn1c(CCc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3ccccn3)ccc21 -US08377923B2,6,CC(C)(C)OC(=O)c1ccc(C#N)cc1C(F)(F)F>>N#Cc1ccc(C(=O)O)c(C(F)(F)F)c1 -US20100016401A1,3,C#C[Si](C)(C)C.Cc1cccc(-c2sc(Br)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)c2c(C)nc3sccn23)c1>>Cc1cccc(-c2sc(C#C[Si](C)(C)C)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)c2c(C)nc3sccn23)c1 -US20100113780A1,8,CCCc1nc(C)n(-c2ccc(OC(C)(C)C(C)O)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1>>CCCc1nc(C)n(-c2ccc(OC(C)(C)C(C)=O)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1 -US20040106653A1,5,CCOC(=O)C(F)(F)F.OCCNCc1ccccc1>>O=C(N(CCO)Cc1ccccc1)C(F)(F)F -US20110207701A1,7,CCOC(=O)CCc1cccc2c1B(O)OC2>>OCCCc1cccc2c1B(O)OC2 -US20080039476A1,2,CC1NCCc2sc(F)cc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2cc(F)sc2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US20030199440A1,1,CC(C)(C)OC(=O)CNS(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.N=C(N)N>>CC(C)(C)OC(=O)CNS(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1 -US20090221555A1,7,CCC1C(=O)N(CC)CCc2cc([N+](=O)[O-])c(OC)cc21>>CCC1C(=O)N(CC)CCc2cc(N)c(OC)cc21 -US20080139607A1,2,COC(=O)[C@@H]1CSc2c(C3CC3)c(Cc3cccc4ccccc34)c(N)c(=O)n21.CS(=O)(=O)Cl>>COC(=O)[C@@H]1CSc2c(C3CC3)c(Cc3cccc4ccccc34)c(NS(C)(=O)=O)c(=O)n21 -US20100093761A1,1,CNC.CS(=O)(=O)c1ccc(-n2ncc3c(O)ncnc32)c(F)c1>>CN(C)c1cc(S(C)(=O)=O)ccc1-n1ncc2c(O)ncnc21 -US04460598,6,COC(=O)CCCCCCCOc1nc(-c2ccccc2)c(-c2ccccc2)n1-c1ccccc1>>O=C(O)CCCCCCCOc1nc(-c2ccccc2)c(-c2ccccc2)n1-c1ccccc1 -US20050020623A1,6,CC(C)(C)OC(=O)N1CCC(Nc2cccc3c(N)nccc23)CC1>>Nc1nccc2c(NC3CCNCC3)cccc12 -US20140378516A1,2,N#Cc1cccc(C(=O)O)c1.Nc1cccc(-c2nnn[nH]2)c1>>N#Cc1cccc(C(=O)Nc2cccc(-c3nnn[nH]3)c2)c1 -US20120184542A1,2,CC(C)(C)OC(=O)N1CCC(N)(c2ccccc2)CC1.COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NC4(c5ccccc5)CCN(C(=O)OC(C)(C)C)CC4)ccc3Cl)c(=O)[nH]c2n1 -US06949536B2,3,CS(=O)(=O)c1ccc(-n2nccc2-c2ccc(Br)cc2)cc1F.OB(O)c1ccco1>>CS(=O)(=O)c1ccc(-n2nccc2-c2ccc(-c3ccco3)cc2)cc1F -US20090118169A1,6,COC(=O)c1ccc2c(c1)n(CCC(C)C)c(=O)n2CCC(C)C>>CC(C)CCn1c(=O)n(CCC(C)C)c2cc(C(=O)O)ccc21 -US04335127,7,CC(C#N)N1CCC(C(=O)c2ccc(F)cc2)CC1>>CC(CN)N1CCC(C(=O)c2ccc(F)cc2)CC1 -US08084620B2,6,CCOC(=O)c1ccc2c(c1)[nH]c1c(C#N)ccc(N3CCC[C@@H](NC(=O)OCc4ccccc4)C3)c12>>N#Cc1ccc(N2CCC[C@@H](NC(=O)OCc3ccccc3)C2)c2c1[nH]c1cc(C(=O)O)ccc12 -US20150072975A1,1,BrCCBr.Sc1cccs1>>BrCCSc1cccs1 -US20110263584A1,3,C[C@@H](c1ccc(Br)cc1)N1CC[C@](CC(C)(C)O)(c2ccc(F)cc2)OC1=O.OB(O)c1ccccn1>>C[C@@H](c1ccc(-c2ccccn2)cc1)N1CC[C@](CC(C)(C)O)(c2ccc(F)cc2)OC1=O -US20040242572A1,2,NCCc1ccc(CN2CCCC2)cc1.O=C(O)c1ccc(-c2ccc(Cl)cc2)cc1[N+](=O)[O-]>>O=C(NCCc1ccc(CN2CCCC2)cc1)c1ccc(-c2ccc(Cl)cc2)cc1[N+](=O)[O-] -US04555362,2,CC(=O)CC(=O)N[C@@H](CC(=O)O)C(=O)O>>CC(=O)CC(=O)N[C@H]1CC(=O)OC1=O -US08394844B2,2,CO.Cc1cccc([C@@H](C)C(=O)O)c1>>COC(=O)[C@H](C)c1cccc(C)c1 -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.Cc1nc(-c2ccc(O)cc2)no1>>Cc1nc(-c2ccc(Oc3ncnc4c3cnn4C3CCN(C(=O)OC(C)(C)C)CC3)cc2)no1 -US05641778,6,CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](C[C@H](CNC(=O)c1ccccc1OCCCOC)C(C)C)NC(=O)OC(C)(C)C>>CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)C[C@H](CNC(=O)c1ccccc1OCCCOC)C(C)C -US20060142247A1,2,CC1(C)C(=O)Nc2cc3[nH]c(-c4n[nH]c5ccc(C(=O)O)cc45)nc3cc21.CCN>>CCNC(=O)c1ccc2[nH]nc(-c3nc4cc5c(cc4[nH]3)NC(=O)C5(C)C)c2c1 -US20150011530A1,6,CC(C)(C)OC(=O)N1CCC2(CC1)CC(n1nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc31)C2>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CC2(CCNCC2)C1 -US20050038065A1,2,CCOC(=O)c1c[nH]c2ccc(OCC)nc2c1=O.NCc1ccccc1>>CCOc1ccc2[nH]cc(C(=O)NCc3ccccc3)c(=O)c2n1 -US07737141B2,7,CCOC(=O)[C@H]1CCC(c2cc(F)c(F)c(F)c2)=N1>>CCOC(=O)[C@H]1CC[C@@H](c2cc(F)c(F)c(F)c2)N1 -US05552431,1,CS(=O)(=O)OCCCC#Cc1ccc(C#N)cc1.[N-]=[N+]=[N-]>>N#Cc1ccc(C#CCCCN=[N+]=[N-])cc1 -US03991045,2,CCCCCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCCCCC.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1>>CCCCCCCCCCCCCCCCCCCCC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1 -US05739132,4,CCCCS(=O)(=O)NC1Cc2ccc(-c3ccc(=O)n(CC#N)n3)cc2C1.[N-]=[N+]=[N-]>>CCCCS(=O)(=O)NC1Cc2ccc(-c3ccc(=O)n(Cc4nnn[nH]4)n3)cc2C1 -US09051333B2,2,CS(=O)(=O)Cl.O=[N+]([O-])c1cn2c(n1)O[C@@H](COc1ccc(N3CCNCC3)cc1)CC2>>CS(=O)(=O)N1CCN(c2ccc(OC[C@H]3CCn4cc([N+](=O)[O-])nc4O3)cc2)CC1 -US20100137610A1,2,CN(c1cccc2cc(C3=NCC(CC(=O)O)S3)[nH]c12)S(=O)(=O)c1cccs1.CS(N)(=O)=O>>CN(c1cccc2cc(C3=NCC(CC(=O)NS(C)(=O)=O)S3)[nH]c12)S(=O)(=O)c1cccs1 -US05744465,7,COc1ccc(CSC2COCC2C#N)cc1>>COc1ccc(CS[C@H]2COC[C@H]2CN)cc1 -US20090281092A1,1,CN1C(=O)C(C)(F)CN(C2CCCCC2)c2nc(Cl)ncc21.COc1cc(C(=O)O)ccc1N>>COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(C)(F)C(=O)N2C -US08501732B2,1,CN1CCCNCC1.O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(Cl)nc1>>CN1CCCN(c2ccc(C(=O)NCc3cn(-c4ccccc4)c4cc(Cl)ccc4c3=O)cn2)CC1 -US20130018055A1,2,Cc1nc(-c2c(F)cc(Cl)cc2-c2ccc3c(c2)CC[C@@H]3NC(=O)C2(N)CC2)no1.O=C(O)c1ccno1>>Cc1nc(-c2c(F)cc(Cl)cc2-c2ccc3c(c2)CC[C@@H]3NC(=O)C2(NC(=O)c3ccno3)CC2)no1 -US04649215,3,O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CCCCCOC1CCCCO1>>O=C/C=C/CCCCOC1CCCCO1 -US20110009454A1,2,Cc1ccccc1CN.Nc1ncccc1C(=O)O>>Cc1ccccc1CNC(=O)c1cccnc1N -US20030083341A1,1,CC(C)(C)OC(=O)CBr.COC(=O)c1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1>>COC(=O)c1cc(-c2ccccc2)c(OCC(=O)OC(C)(C)C)c(-c2ccccc2)c1 -US08058045B2,1,O=C(CCl)NC[C@H](O)CO>>O=C1CO[C@H](CO)CN1 -US20070185089A1,2,CS(=O)(=O)Cl.O=C1O[C@@H](CO)CN1c1ccc2c(c1)CCN(C1CCC1)CC2>>CS(=O)(=O)OC[C@H]1CN(c2ccc3c(c2)CCN(C2CCC2)CC3)C(=O)O1 -US20090227601A1,1,C1CCNC1.Cc1cc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)N2CCC(COS(C)(=O)=O)CC2)c(C)cc1Cl>>Cc1cc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)N2CCC(CN3CCCC3)CC2)c(C)cc1Cl -US20060135785A1,6,CCCCCCCCCCCCS(=O)(=O)C(F)(C(=O)OC)c1ccccc1>>CCCCCCCCCCCCS(=O)(=O)C(F)(C(=O)O)c1ccccc1 -US07994171B2,2,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)ccc3C)cc12.NC1(c2ncc(F)cn2)CC1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5ncc(F)cn5)CC4)ccc3C)cc12 -US08546427B2,2,CC1(C)CC(c2cccc(N)c2)Nc2ccc(Cl)cc21.CCS(=O)(=O)Cl>>CCS(=O)(=O)Nc1cccc(C2CC(C)(C)c3cc(Cl)ccc3N2)c1 -US20100317676A1,6,c1ccc(CN2CCc3ncnc(Nc4ccccc4)c3C2)cc1>>c1ccc(Nc2ncnc3c2CNCC3)cc1 -US04442103,1,C1CNCCN1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1N1CCNCC1 -US20040122007A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COc1ccc2ccc(OS(=O)(=O)C(F)(F)F)cc2c1>>C=Cc1ccc2ccc(OC)cc2c1 -US04529737,1,CC(C)Cc1ccc(C(C)C(=O)[O-])cc1.O=C1OC(Br)c2ccccc21>>CC(C)Cc1ccc(C(C)C(=O)OC2OC(=O)c3ccccc32)cc1 -US20060270706A1,1,COC(=O)Cn1nncc1/C=C1\CNCCC1SC(C)=O.O=C(C1CC1)C(Br)c1ccccc1F>>COC(=O)Cn1nncc1/C=C1\CN(C(C(=O)C2CC2)c2ccccc2F)CCC1SC(C)=O -US04801610,2,CC(C)(C)C(=O)Cl.O=C(c1ccccc1)c1ccc(O)cc1>>CC(C)(C)C(=O)Oc1ccc(C(=O)c2ccccc2)cc1 -US20030199578A1,2,Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12.O=C(Cl)c1cc(Cl)cc(Cl)c1>>O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)c1cc(Cl)cc(Cl)c1 -US20040053955A1,7,C=Cc1nc(C)ccc1C#N>>CCc1nc(C)ccc1C#N -US05550129,1,CCOc1ccc2c(C)c(CCCl)c(=O)oc2c1OCC.COc1ccccc1N1CCNCC1>>CCOc1ccc2c(C)c(CCN3CCN(c4ccccc4OC)CC3)c(=O)oc2c1OCC -US20120208819A1,7,COC(=O)c1nc(Br)cnc1N>>Nc1ncc(Br)nc1CO -US06498125B2,8,CCOC(=O)c1ccc(SCC)nc1C(F)(F)F.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1ccc(S(=O)CC)nc1C(F)(F)F -US20100016396A1,1,COC(=O)[C@H](C)Oc1cc(Oc2c(C=O)c(C)nn2C)c(Cl)cc1Cl.N#CCN>>COC(=O)[C@H](C)Oc1cc(Oc2c(/C=N/CC#N)c(C)nn2C)c(Cl)cc1Cl -US20100035871A1,3,CN1CC(CN=[N+]=[N-])Oc2c(Br)cccc21.Cc1ccccc1B(O)O>>Cc1ccccc1-c1cccc2c1OC(CN=[N+]=[N-])CN2C -US07834051B2,1,C[C@@H]1NC(=O)C[C@]1(C)O.N#Cc1ccc(Br)cc1Cl>>C[C@@H]1N(c2ccc(C#N)c(Cl)c2)C(=O)C[C@]1(C)O -US20040204584A1,3,CCCC[Sn](CCCC)(CCCC)C1=CCOCC1.COc1ccc(C2COCCO2)c2sc(NC(=O)c3ccnc(Br)c3)nc12>>COc1ccc(C2COCCO2)c2sc(NC(=O)c3ccnc(C4=CCOCC4)c3)nc12 -US20150266857A1,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)c2ccc(F)cc21.O=C1NS(=O)(=O)c2ccc(Br)cc21>>CC(C)(C)OC(=O)n1cc(-c2ccc3c(c2)C(=O)NS3(=O)=O)c2ccc(F)cc21 -US06407096B1,1,COC(=O)CBr.O=C(CN1C(=O)COc2c(O)cccc21)NC(c1ccccc1)c1ccccc1>>COC(=O)COc1cccc2c1OCC(=O)N2CC(=O)NC(c1ccccc1)c1ccccc1 -US08227492B2,1,CC(=O)Cl.N=S(=O)(CCO)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1>>CC(=O)N=S(=O)(CCO)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 -US20090076081A1,1,CCN.O=C1CCN(C(=O)OCc2ccccc2)CC1>>CCNC1CCN(C(=O)OCc2ccccc2)CC1 -US04922021,2,Cc1cccc(C)c1NCC(C)O.O=C(Cl)c1ccccc1>>Cc1cccc(C)c1N(CC(C)O)C(=O)c1ccccc1 -US20150094302A1,7,CCOC(=O)c1cc2c(n1CC#N)CCCC2>>CCOC(=O)c1cc2c(n1CCN)CCCC2 -US06927228B2,3,CCN(Cc1cccc(-c2ccc(C=O)cc2)c1)C(=O)OC(C)(C)C.O=C1CSC(=O)N1>>CCN(Cc1cccc(-c2ccc(C=C3SC(=O)NC3=O)cc2)c1)C(=O)OC(C)(C)C -US04107438,1,N#CCCCl.Sc1ccc(Cl)cc1>>N#CCCSc1ccc(Cl)cc1 -US20080015203A1,9,CC(C)n1ccc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3Cl)cc(O[C@@H](C)CO)c2)n1>>CC(C)n1ccc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3)cc(O[C@@H](C)CO)c2)n1 -US20100004292A1,2,CC(C)(C)[Si](C)(C)OCCNc1ccc(N)cc1.O=C(Nc1cnccc1C(=O)O)c1ccc(Cl)s1>>CC(C)(C)[Si](C)(C)OCCNc1ccc(NC(=O)c2ccncc2NC(=O)c2ccc(Cl)s2)cc1 -US20110124634A1,6,CCOC(=O)c1ncc(C(=O)OC(C)(C)C)[nH]1>>CCOC(=O)c1ncc(C(=O)O)[nH]1 -US05504207,1,COc1cc2nc(Cl)nc(N)c2cc1OC.O=C(C1CCCO1)N1CCNCC1>>COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC -US20040162282A1,2,CN(C)Cc1cc(N2CCNCC2)ccc1Cl.Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O>>Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccc(Cl)c(CN(C)C)c2)CC1 -US08063099B2,6,CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2[C@H]1CNCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2[C@H]1CN -US20090253677A1,2,CCOC(=O)c1nc2n(c(=O)c1O)C[C@H]1CC[C@@](C)(C2NC(=O)OCc2ccccc2)C1(C)C.NCc1ccc(F)cc1>>CC1(C)[C@@H]2CC[C@@]1(C)[C@@H](NC(=O)OCc1ccccc1)c1nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n1C2 -US05514643,1,CCN.N#CC(NC(=O)c1sc(Br)nc1C(F)(F)F)c1cccs1>>CCNc1nc(C(F)(F)F)c(C(=O)NC(C#N)c2cccs2)s1 -US20150274664A1,6,CC(C)(C)OC(=O)N1CCC([C@H]2C[C@@H]2CCNc2ncc(-n3cnnn3)cn2)CC1>>c1nc(NCC[C@H]2C[C@@H]2C2CCNCC2)ncc1-n1cnnn1 -US07557127B2,6,CCCCN1CC[C@@H](N(C(=O)OC(C)(C)C)c2ccc(/C=C/C(=O)OCC)cn2)C1>>CCCCN1CC[C@@H](N(C(=O)OC(C)(C)C)c2ccc(/C=C/C(=O)O)cn2)C1 -US05998433,2,O=C(O)c1ccc(C(=O)c2ccccc2)cc1.c1cc2c(o1)CNCCC2>>O=C(c1ccccc1)c1ccc(C(=O)N2CCCc3ccoc3C2)cc1 -US20020173654A1,2,CCCCc1nc2c(N)nc3cccnc3c2n1CCCCN.O=C(Cl)c1cccnc1>>CCCCc1nc2c(N)nc3cccnc3c2n1CCCCNC(=O)c1cccnc1 -US20090099195A1,9,CC(C)N1Cc2c(NCc3cnc4ccccc4c3)nc(Cl)nc2C1=O>>CC(C)N1Cc2c(NCc3cnc4ccccc4c3)ncnc2C1=O -US20110263647A1,7,COC(=O)c1nc(NC[C@@H](N)Cc2ccc(C(F)(F)F)cc2)sc1-c1ccc2cnc(F)cc2c1>>N[C@H](CNc1nc(CO)c(-c2ccc3cnc(F)cc3c2)s1)Cc1ccc(C(F)(F)F)cc1 -US20080132539A1,1,Cc1cc2nc(CC[C@H](NC(=O)OC(C)(C)C)C(=O)OCc3ccccc3)[nH]c2cc1C.O=[N+]([O-])c1cccc(B(O)O)c1>>Cc1cc2nc(CC[C@H](NC(=O)OC(C)(C)C)C(=O)OCc3ccccc3)n(-c3cccc([N+](=O)[O-])c3)c2cc1C -US20060122176A1,3,CNc1ncnc2ccc(C=O)cc12.O=C1CSC(=O)N1>>CNc1ncnc2ccc(C=C3SC(=O)NC3=O)cc12 -US08664220B2,1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4N)cc3)cc2)CC1.O=C(NC1CC1)c1cccc(Br)n1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cccc(C(=O)NC5CC5)n4)cc3)cc2)CC1 -US20050101644A1,2,O=C(O)C1(O)CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1.OCCN1CCNCC1>>O=C(N1CCN(CCO)CC1)C1(O)CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1 -US09051333B2,1,O=[N+]([O-])c1cn(CC[C@@H](O)COc2ccc3nc(N4CCN(Cc5ccc(OC(F)(F)F)cc5)CC4)sc3c2)c(Cl)n1>>O=[N+]([O-])c1cn2c(n1)O[C@@H](COc1ccc3nc(N4CCN(Cc5ccc(OC(F)(F)F)cc5)CC4)sc3c1)CC2 -US20030134854A1,1,COCCO.COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccnc(Cl)c3)nc12>>COCCOc1cc(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)ccn1 -US04988686,8,CN(C)CCn1cc(OC(c2ccccc2)c2ccccc2)c(=O)cc1CO>>CN(C)CCn1cc(OC(c2ccccc2)c2ccccc2)c(=O)cc1C=O -US20120238750A1,3,C#Cc1ccc(C(F)(F)F)cc1.COc1ccc(CN2CCCN(c3ccc(Oc4ccc(Br)cn4)c(C)c3)C2=O)cc1OC>>COc1ccc(CN2CCCN(c3ccc(Oc4ccc(C#Cc5ccc(C(F)(F)F)cc5)cn4)c(C)c3)C2=O)cc1OC -US20060035956A1,1,CCOC(=O)CBr.O=C(CCC#Cc1ccc(C(F)(F)F)cc1)NCc1ccc2cc[nH]c2c1>>CCOC(=O)Cn1ccc2ccc(CNC(=O)CCC#Cc3ccc(C(F)(F)F)cc3)cc21 -US07176242B2,9,CCCN(CCC)C(=O)c1cc(CBr)cc(C(=O)OCC)c1.[C-]#N>>CCCN(CCC)C(=O)c1cc(CC#N)cc(C(=O)OCC)c1 -US20110124618A1,1,CCN.CS(=O)(=O)OCCCOc1cccc(-c2cc(C(=O)N3CNC(=O)C3)nn2-c2cccc(Cl)c2)c1>>CCNCCCOc1cccc(-c2cc(C(=O)N3CNC(=O)C3)nn2-c2cccc(Cl)c2)c1 -US08906941B2,2,CCOC(=O)C(O)C([NH3+])Cc1ccccc1.O=C(O)c1cccnc1-c1csc(-c2ccccc2)n1>>CCOC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-c1csc(-c2ccccc2)n1 -US08058300B2,2,Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1NC(=O)O[C@H](C)c1ccccc1.NS(=O)(=O)c1ccccc1>>Cc1noc(-c2ccc(-c3ccc(C4(C(=O)NS(=O)(=O)c5ccccc5)CC4)cc3)cc2)c1NC(=O)O[C@H](C)c1ccccc1 -US04942245,1,CCCc1c(OCCBr)ccc(C(C)=O)c1O.CCOC(=O)c1ccc2nc(S)[nH]c2c1>>CCCc1c(OCCSc2nc3ccc(C(=O)OCC)cc3[nH]2)ccc(C(C)=O)c1O -US20150225404A1,1,Cc1ncc(-c2cc(Cl)nc3c2CCC3)cn1.N#Cc1ccc(CO)nc1>>Cc1ncc(-c2cc(OCc3ccc(C#N)cn3)nc3c2CCC3)cn1 -US20100022529A1,1,OCc1ccccc1.Oc1cc2cn[nH]c2cc1Br>>Brc1cc2[nH]ncc2cc1OCc1ccccc1 -US20150252397A1,9,COc1cc(C(=O)O)ccc1O>>COc1cc(C=O)ccc1O -US06329547B1,3,CC(=O)c1ccc(C(=O)OC(C)(C)C)cc1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=C(C)c1ccc(C(=O)OC(C)(C)C)cc1 -US06515142B2,10,Cc1ccc2ccc(C#N)cc2c1.O=C1CCC(=O)N1Br>>N#Cc1ccc2ccc(CBr)cc2c1 -US08518972B2,7,CN(C)S(=O)(=O)c1ccc(C(=O)O)cc1>>CN(C)S(=O)(=O)c1ccc(CO)cc1 -US04777267,1,Cc1oc(=O)oc1CCl.Sc1ccc(Cl)cc1>>Cc1oc(=O)oc1CSc1ccc(Cl)cc1 -US20130165436A1,2,CC(=O)Cl.COc1ncc(N2CCOc3ccc(O[C@H]4CCN(C(=O)[C@H]5CCNC5)C4)cc32)cc1C#N>>COc1ncc(N2CCOc3ccc(O[C@H]4CCN(C(=O)[C@H]5CCN(C(C)=O)C5)C4)cc32)cc1C#N -US20090054407A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1ccc2[nH]ccc2c1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc3[nH]ccc3c2)CC1 -US20040157817A1,2,CC(C)S(=O)(=O)Cl.CC(C)S(=O)(=O)NC1CCCC=C1c1ccc(OCCN)cc1>>CC(C)S(=O)(=O)NCCOc1ccc(C2=CCCCC2NS(=O)(=O)C(C)C)cc1 -US20130231328A1,9,CC(C)(C)OC(=O)NCCc1cc2c(O)ncnc2s1.ClC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)NCCc1cc2c(Cl)ncnc2s1 -US07863454B2,3,CC(C)c1n[nH]c2cccc(B(O)O)c12.Cc1ccc(C(C)C)cc1OCc1c(OC(C)C)cc(Cl)nc1C>>Cc1ccc(C(C)C)cc1OCc1c(OC(C)C)cc(-c2cccc3[nH]nc(C(C)C)c23)nc1C -US09040522B2,2,C1CCN(C2CCCNC2)CC1.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)N3CCCC(N4CCCCC4)C3)cn2)c1O -US05420122,6,COC(OC)c1nc([C@@H]2C[C@@H](OS(C)(=O)=O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)cs1>>CS(=O)(=O)O[C@@H]1C[C@@H](c2csc(C=O)n2)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1 -US08569535B2,6,CCOC(=O)C1(NC(=O)c2cccc3cc(C)oc23)Cc2ccccc2C1>>Cc1cc2cccc(C(=O)NC3(C(=O)O)Cc4ccccc4C3)c2o1 -US20050215578A1,1,Clc1ccc(CSc2nsc(Cl)n2)cc1.OCc1ccccc1>>Clc1ccc(CSc2nsc(OCc3ccccc3)n2)cc1 -US20090253687A1,4,Cc1ccccc1NN.O=C1COc2ccc(C(=O)CC(=O)C(F)(F)F)cc2N1>>Cc1ccccc1-n1nc(C(F)(F)F)cc1-c1ccc2c(c1)NC(=O)CO2 -US06605620B1,1,COc1cc(-c2cncc(CCl)c2)cc(OC)c1OC.COc1cccc(NC2CCN(C(=O)OC(C)(C)C)CC2)c1>>COc1cccc(N(Cc2cncc(-c3cc(OC)c(OC)c(OC)c3)c2)C2CCN(C(=O)OC(C)(C)C)CC2)c1 -US20120029187A1,4,CC(C)=CC(=O)NCc1ccccc1[N+](=O)[O-].O=C(OO)c1cccc(Cl)c1>>CC1(C)OC1C(=O)NCc1ccccc1[N+](=O)[O-] -US20150175617A1,5,COC(=O)c1cc(F)cc(N)c1Br.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(F)cc(NC(=O)C(F)(F)F)c1Br -US20100041892A1,6,CCOC(=O)/C=C/c1ccc(OCCOC)cc1NC(=O)c1ccc(Cl)cc1Cl>>COCCOc1ccc(/C=C/C(=O)O)c(NC(=O)c2ccc(Cl)cc2Cl)c1 -US20150045368A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C([NH3+])c1ccccc1F>>COC(=O)C(NC(=O)OC(C)(C)C)c1ccccc1F -US04398029,1,CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21.OCCBr>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(CCO)CC3)c(F)c21 -US05053422,2,CC(C)COC(=O)CCC1NC(=O)[C@H](Cc2ccccc2)N1>>O=C1NC2CCC(=O)N2[C@H]1Cc1ccccc1 -US20100029619A1,6,CCOC(=O)CC(C)(C)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1>>CC(C)(CC(=O)O)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1 -US20110218200A1,1,C1CNCCN1.O=[N+]([O-])c1ccc(Br)cc1Nc1ccccc1>>O=[N+]([O-])c1ccc(N2CCNCC2)cc1Nc1ccccc1 -US04981768,1,O=[N+]([O-])c1ccc(Cl)cc1.c1ccc2c(c1)[nH]c1ccccc12>>O=[N+]([O-])c1ccc(-n2c3ccccc3c3ccccc32)cc1 -US20100197687A1,2,CCOC(=O)C(=O)Cl.Nc1ccc(Cl)cc1C(=O)C(F)(F)F>>CCOC(=O)C(=O)Nc1ccc(Cl)cc1C(=O)C(F)(F)F -US20110269738A1,3,CC(C)Oc1ccc(-c2nnc(Br)s2)cc1Cl.CCc1c(/C=C/OC)cccc1B1OC(C)(C)C(C)(C)O1>>CCc1c(/C=C/OC)cccc1-c1nnc(-c2ccc(OC(C)C)c(Cl)c2)s1 -US20020032168A1,9,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(Cl)nc(Cl)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.N#C[Cu]>>CC(=O)OC[C@H]1O[C@@H](n2cnc3c(Cl)nc(C#N)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O -US08309734B2,1,O=C(O)c1cccnc1Cl.Oc1cccc(C(F)(F)F)c1>>O=C(O)c1cccnc1Oc1cccc(C(F)(F)F)c1 -US08796280B2,1,CCc1nc2ccccc2[nH]1.O=S(=O)(Nc1nccnc1-c1ccc(CCl)cc1)c1ccccc1C(F)(F)F>>CCc1nc2ccccc2n1Cc1ccc(-c2nccnc2NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 -US08236984B2,6,COC(=O)c1ccccc1Nc1cc(Cl)c(OCc2ccccc2)c(Cl)c1>>COC(=O)c1ccccc1Nc1cc(Cl)c(O)c(Cl)c1 -US06225481B1,1,CO.COc1ccc(-c2cc(=O)c3c(O)c(I)c(OC)cc3o2)cc1>>COc1ccc(-c2cc(=O)c3c(OC)c(I)c(OC)cc3o2)cc1 -US20090137804A1,2,CCN1CCN(c2ccc(Nc3cc(N)ncn3)cc2)CC1.COc1cc(OC)c(Cl)c(N=C=O)c1Cl>>CCN1CCN(c2ccc(Nc3cc(NC(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)cc2)CC1 -US20130172556A1,2,CCOC(=O)C(=O)c1c(CC)cc(C)cc1CC.NN>>CCc1cc(C)cc(CC)c1C(=O)C(=O)NN -US20060217380A1,3,C#Cc1cnc(N)nc1.Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1I>>Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1cnc(N)nc1 -US07863332B2,6,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2C)c1>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)O)cc2C)c1 -US07915411B2,3,C=Cc1ccccc1.Cc1ccc(Br)cc1[N+](=O)[O-]>>Cc1ccc(C=Cc2ccccc2)cc1[N+](=O)[O-] -US20140309227A1,3,C[C@@H]1CN(Cc2ccc3c(Cl)cc(C#N)nc3c2)C[C@H](C(F)(F)F)O1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>C[C@@H]1CN(Cc2ccc3c(-c4cnn(C)c4)cc(C#N)nc3c2)C[C@H](C(F)(F)F)O1 -US04906634,1,CCN(CC)CCCl.O=[N+]([O-])c1ccc(S)cc1>>CCN(CC)CCSc1ccc([N+](=O)[O-])cc1 -US05707991,6,COC(=O)Cc1cccc(NC(=O)NCC(=O)N2C(C(=O)NCC(C)C)CC(S(=O)(=O)c3ccccc3)C2c2ccccc2F)c1>>CC(C)CNC(=O)C1CC(S(=O)(=O)c2ccccc2)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(CC(=O)O)c1 -US20150065482A1,1,BrCCBr.NC(=O)c1nn(-c2cccc(I)c2)c2ccc(O)cc12>>NC(=O)c1nn(-c2cccc(I)c2)c2ccc(OCCBr)cc12 -US20090270381A1,3,C#Cc1ccccc1.N#Cc1ccc(NC(=O)C(=O)C2CCCCC2)cc1Cl>>N#Cc1ccc(NC(=O)C(O)(C#Cc2ccccc2)C2CCCCC2)cc1Cl -US05534634,1,FC(F)(F)CCl.Sc1ccc(Cl)cc1>>FC(F)(F)CSc1ccc(Cl)cc1 -US08637525B2,1,CN.Fc1ccc(C2OCc3c(Cl)nc(Cl)nc32)cc1>>CNc1nc(Cl)nc2c1COC2c1ccc(F)cc1 -US20110130468A1,6,C[Si](C)(C)C#Cc1ccc(OC2CCCCO2)cc1>>C#Cc1ccc(OC2CCCCO2)cc1 -US20040209921A1,1,CN(CCCCNC1CCCc2cccnc21)C(=O)OC(C)(C)C.Cc1cnc(C=O)c(C)c1>>Cc1cnc(CN(CCCCN(C)C(=O)OC(C)(C)C)C2CCCc3cccnc32)c(C)c1 -US06703392B2,1,CCI.COc1ccc(CC2c3c(O)ccc(OC)c3CCN2CC(=O)NCc2ccccn2)cc1OC>>CCOc1ccc(OC)c2c1C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NCc1ccccn1)CC2 -US08471005B2,7,COc1cc(CN2CCC(O)CC2)ccc1[N+](=O)[O-]>>COc1cc(CN2CCC(O)CC2)ccc1N -US05863917,7,CCc1cc([N+](=O)[O-])c(N)cc1Cl>>CCc1cc(N)c(N)cc1Cl -US20090176774A1,2,COc1ccc(Oc2ccc3c(C(=O)Cl)cccc3c2)cn1.Nc1ccc(F)c(Cl)c1>>COc1ccc(Oc2ccc3c(C(=O)Nc4ccc(F)c(Cl)c4)cccc3c2)cn1 -US20020173646A1,8,CCSCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC.O=S([O-])OO>>CCS(=O)CCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC -US09023865B2,1,COC[C@@H](NC(N)=O)c1ccccc1.Cn1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc(Cl)ncc23)cn1>>COC[C@@H](NC(=O)Nc1cc2c(cn1)c(-c1cnn(C)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1 -US20030064992A1,1,NCCc1ccncc1.O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Br>>O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCCc1ccncc1 -US20050004186A1,3,C#C[Si](C)(C)C.OCC(CO)Nc1nnc(-c2ccc(F)c(F)c2Nc2ccc(I)cc2F)o1>>C[Si](C)(C)C#Cc1ccc(Nc2c(-c3nnc(NC(CO)CO)o3)ccc(F)c2F)c(F)c1 -US20100063087A1,2,CC(=O)O.COCCCC(N)c1cc(Br)ccn1>>COCCCC(NC(C)=O)c1cc(Br)ccn1 -US20120214767A1,6,CCCc1ccc(-n2ncc3c2CCc2cc(OC)ccc2-3)cc1>>CCCc1ccc(-n2ncc3c2CCc2cc(O)ccc2-3)cc1 -US20020103384A1,6,CC(C)(C)OC(=O)N[C@H](C(=O)N1CC=C[C@H]1C#N)C(C)(C)C>>CC(C)(C)[C@H](N)C(=O)N1CC=C[C@H]1C#N -US20120289522A1,2,CS(N)(=O)=O.O=C(O)C1(c2ccc(Br)cc2)CC1>>CS(=O)(=O)NC(=O)C1(c2ccc(Br)cc2)CC1 -US20150119411A1,1,BrCc1ccc(Br)cc1.COCCCNC(=O)c1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1>>COCCCNC(=O)c1ccc(Cn2c(=O)c3ccccc3n(Cc3ccc(Br)cc3)c2=O)cc1 -US20070232615A1,1,CN(C)[C@H]1CCNC1.CN(Cc1cn2c(F)cccc2n1)[C@H]1CCCc2cccnc21>>CN(C)[C@H]1CCN(c2cccc3nc(CN(C)[C@H]4CCCc5cccnc54)cn23)C1 -US08124629B2,2,CN.Cc1cc(S(=O)(=O)Cl)ccc1Br>>CNS(=O)(=O)c1ccc(Br)c(C)c1 -US20100048636A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]([C@@](C)(OCCO)c2cccc(Cl)c2)C1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCC[C@@H]([C@@](C)(OCCN2C(=O)c3ccccc3C2=O)c2cccc(Cl)c2)C1 -US20060183758A1,3,C#C[Si](C)(C)C.Nc1ncc(Br)cc1I>>C[Si](C)(C)C#Cc1cc(Br)cnc1N -US20120277208A1,1,BrCc1ccccc1.COC(=O)c1cc(O)cc(Oc2ccc([N+](=O)[O-])cc2)c1>>COC(=O)c1cc(OCc2ccccc2)cc(Oc2ccc([N+](=O)[O-])cc2)c1 -US20110152240A1,3,O=C1CNC(=O)N1.O=Cc1cnn2c(NC3CC3)cc(Nc3cc(F)cc(F)c3)nc12>>O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(Nc4cc(F)cc(F)c4)nc23)N1 -US06143764,1,COc1cc2nccc(Cl)c2cc1OC.Cc1ccc(C(=O)c2ccc(O)cc2)cc1>>COc1cc2nccc(Oc3ccc(C(=O)c4ccc(C)cc4)cc3)c2cc1OC -US20080167321A1,2,CCCCCCN.COC(=O)c1ccnc(N2CCN(C(=O)c3cc(F)ccc3C(F)(F)F)CC2)c1>>CCCCCCNC(=O)c1ccnc(N2CCN(C(=O)c3cc(F)ccc3C(F)(F)F)CC2)c1 -US06194406B1,1,CCOCCn1c(N2CCCNCC2)nc2ccccc21.CS(=O)(=O)OCCC1(c2ccccc2)CCN(C(=O)OCc2ccccc2)C1>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)OCc4ccccc4)C3)CC2)nc2ccccc21 -US08476265B2,6,CC(C)(C)OC(=O)N1CCOC2(CN(CCc3cccc(CCO)c3)C2)C1>>OCCc1cccc(CCN2CC3(CNCCO3)C2)c1 -US20070254877A1,3,CN(C)C=O.O=C1CCCCc2c1[nH]c1ccccc21>>CN(C)C=C1CCCc2c([nH]c3ccccc23)C1=O -US08546383B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(N)CN>>C[C@H](N)CNC(=O)OC(C)(C)C -US20100063286A1,1,Cc1cccc(N2CCNCC2)c1C.O=CCCc1cc(-c2ccc(Cl)cc2)n(-c2ccccc2)n1>>Cc1cccc(N2CCN(CCCc3cc(-c4ccc(Cl)cc4)n(-c4ccccc4)n3)CC2)c1C -US20120114765A1,6,CC(C)(C)[Si](C)(C)OCCCNC(=O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(NCCCO)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US20140011881A1,2,CCc1cc(C(F)(F)F)cc(CC)c1C=CC(=O)O.C[C@@H](N)c1cc(F)c(NS(C)(=O)=O)c(F)c1>>CCc1cc(C(F)(F)F)cc(CC)c1C=CC(=O)N[C@H](C)c1cc(F)c(NS(C)(=O)=O)c(F)c1 -US20120202828A1,7,C[C@H]1OC[C@]2(c3cc([N+](=O)[O-])ccc3F)N=C(NC(=O)OC(C)(C)C)N(C)C(=O)[C@H]12>>C[C@H]1OC[C@]2(c3cc(N)ccc3F)N=C(NC(=O)OC(C)(C)C)N(C)C(=O)[C@H]12 -US20140275080A1,7,Cc1cn(-c2cc(Oc3ccc([N+](=O)[O-])nc3C)ccn2)cn1>>Cc1cn(-c2cc(Oc3ccc(N)nc3C)ccn2)cn1 -US07666888B2,2,COc1ccc(-c2nocc2C(=O)O)cc1Cl.Cc1cc(C2(O)CCNC2)ccc1F>>COc1ccc(-c2nocc2C(=O)N2CCC(O)(c3ccc(F)c(C)c3)C2)cc1Cl -US20080287517A1,6,CCOC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OCCCF)cc2)c1C>>Cc1c(C(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCCCF)cc1 -US20110028467A1,2,COc1c(Br)cc(C(=O)Cl)cc1Br.Cc1ccc2c(n1)OCCN2>>COc1c(Br)cc(C(=O)N2CCOc3nc(C)ccc32)cc1Br -US20140350030A1,8,O=C(NC12CC3CC(CC(CO)(C3)C1)C2)c1cccc(Cl)c1>>O=CC12CC3CC(C1)CC(NC(=O)c1cccc(Cl)c1)(C3)C2 -US05206240,1,CC(=O)c1cc(CCl)ccc1O.O=C1NCCN1>>CC(=O)c1cc(CN2CCNC2=O)ccc1O -US20120252815A1,1,CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(N)CC4)n3)ccc21.O=CCCCCO>>CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(NCCCCCO)CC4)n3)ccc21 -US05817652,3,CCC1(C=O)CSc2ccccc2C(c2ccccc2)=N1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=CC1(CC)CSc2ccccc2C(c2ccccc2)=N1 -US20100184770A1,6,CC(C)(C)OC(=O)NCCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O>>NCCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O -US20150183763A1,1,C[C@@H](O)C(F)(F)F.Fc1cccc(CBr)c1>>C[C@@H](OCc1cccc(F)c1)C(F)(F)F -US20150080393A1,6,CCOC(=O)[C@@H]1CC2(CCN(c3cc(OC(c4ccc(C#N)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1>>Cc1ccn(-c2cc(C#N)ccc2[C@@H](Oc2cc(N3CCC4(CC3)CN[C@H](C(=O)O)C4)nc(N)n2)C(F)(F)F)n1 -US06399619B1,1,BrCc1ccccc1.O=C(O)[C@@H](O)CC1CCC1>>O=C(OCc1ccccc1)[C@@H](O)CC1CCC1 -US20060116410A1,2,CNC(=O)COc1cc(C#N)ccc1CN.Cc1nc(C(=O)O)co1>>CNC(=O)COc1cc(C#N)ccc1CNC(=O)c1coc(C)n1 -US06693123B2,3,C=Cc1cccnc1.COC(=O)[C@H](CCSC)NC(=O)c1ccc(I)cc1-c1ccccc1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(C=Cc2cccnc2)cc1-c1ccccc1 -US20090018134A1,2,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)CCCOC(F)F)CC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)CCCOC(F)F)CC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US07667053B2,7,CCOC(=O)C1COc2ccccc2C1=O>>CCOC(=O)C1COc2ccccc2C1 -US20140249132A1,1,CC1(C)OB(c2cnn(CCCl)c2)OC1(C)C.CNC>>CN(C)CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1 -US20030203900A1,2,CNOC.C[C@@H](OC(C)(C)C)[C@@H](C(=O)O)N(C(=O)OCc1ccccc1)[SiH](C)C>>CON(C)C(=O)[C@H]([C@@H](C)OC(C)(C)C)N(C(=O)OCc1ccccc1)[SiH](C)C -US05416103,2,CCC(C)[C@@H]1CCCC[C@H]1N.Cc1nc(C(F)(F)F)c(C(=O)Cl)s1>>CCC(C)[C@@H]1CCCC[C@H]1NC(=O)c1sc(C)nc1C(F)(F)F -US05807885,1,Fc1cccc(CBr)c1.O=C(NCCc1ccc([N+](=O)[O-])cc1)C(F)(F)F>>O=C(N(CCc1ccc([N+](=O)[O-])cc1)Cc1cccc(F)c1)C(F)(F)F -US09133171B2,1,COc1cc(F)ccc1-c1nc(Cl)ncc1F.CSCc1cc(N)cc(Br)c1>>COc1cc(F)ccc1-c1nc(Nc2cc(Br)cc(CSC)c2)ncc1F -US20020032187A1,6,COC(=O)C[C@@H]1Cc2ccc(OCCCNc3ccccn3)cc2CN(CCc2ccccc2)C1=O>>O=C(O)C[C@@H]1Cc2ccc(OCCCNc3ccccn3)cc2CN(CCc2ccccc2)C1=O -US20140213554A1,3,CC1(C)OB(c2ccc(P(C)(C)=O)cc2)OC1(C)C.Cc1n[nH]c(C(=O)Nc2cnc3[nH]c(I)cc3c2)c1C>>Cc1n[nH]c(C(=O)Nc2cnc3[nH]c(-c4ccc(P(C)(C)=O)cc4)cc3c2)c1C -US20140275108A1,6,COC(=O)[C@H](CNC(=O)OC(C)(C)C)N1CCN(C(=O)C(C)C)CC1>>CC(C)C(=O)N1CCN([C@@H](CNC(=O)OC(C)(C)C)C(=O)O)CC1 -US20090326009A1,7,COC(=O)c1cc([N+](=O)[O-])ccc1Br>>COC(=O)c1cc(N)ccc1Br -US06245746B1,1,CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)O.O=Cc1ccccc1>>CC(C)(C)OC(=O)NCCC[C@H](NCc1ccccc1)C(=O)O -US20020016328A1,1,CCC(N)C(C)O.COC(=O)c1c(Cl)cc(C)nc1Oc1c(C)cc(C)cc1C>>CCC(Nc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1C(=O)OC)C(C)O -US20140350019A1,1,CCOC(=O)CBr.Oc1cccc(NCc2cc(-c3cccc(F)c3)ccc2F)c1>>CCOC(=O)COc1cccc(NCc2cc(-c3cccc(F)c3)ccc2F)c1 -US20060247250A1,2,CC(C)NCCO.O=C(Cl)c1cccc(Br)c1>>CC(C)N(CCO)C(=O)c1cccc(Br)c1 -US07709481B2,1,N#Cc1ccc(F)cc1Cl.OCc1sc(-c2ccc(C(F)(F)F)nc2)nc1CCCOCc1ccccc1>>N#Cc1ccc(OCc2sc(-c3ccc(C(F)(F)F)nc3)nc2CCCOCc2ccccc2)cc1Cl -US04877811,6,CCOC(=O)CCCc1ccc(-c2ccccc2)cc1>>O=C(O)CCCc1ccc(-c2ccccc2)cc1 -US08399465B2,6,CCOC(=O)c1coc2cc(OC)ccc12>>CCOC(=O)c1coc2cc(O)ccc12 -US20110201580A1,1,CC(=O)OCC(=O)[C@@]12CNC[C@@H]1C[C@H]1[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C.CC(C)(C)CC=O>>CC(=O)OCC(=O)[C@@]12CN(CCC(C)(C)C)C[C@@H]1C[C@H]1[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C -US07851473B2,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1nc(-c2ccoc2)ns1>>CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccoc3)ns2)CC1 -US20100075961A1,10,C=CCC(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)CNC(=O)NC(C)(C)C.O>>CC(C)(C)NC(=O)NCC(C)(C)C(CCCO)c1ccc2c(cnn2-c2ccc(F)cc2)c1 -US20030119807A1,6,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)N2CCC(c3ccncc3)CC2)no1>>O=C(O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)N2CCC(c3ccncc3)CC2)no1 -US05102890,1,O=C1CCC(C(=O)O)N1.O=C1c2ccccc2C(Cl)N1c1ccc2ccc(Cl)nc2n1>>O=C1CCC(C(=O)OC2c3ccccc3C(=O)N2c2ccc3ccc(Cl)nc3n2)N1 -US08173650B2,2,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCNCC3(C)C)n(C)c2n1.C[C@@H](O)C(=O)O>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(=O)[C@@H](C)O)CC3(C)C)n(C)c2n1 -US08354422B2,1,CNC.O=[N+]([O-])c1ccc(CCBr)cc1>>CN(C)CCc1ccc([N+](=O)[O-])cc1 -US06355680B1,1,Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.O=C(O)Cc1ccccc1Br>>O=C(O)Cc1ccccc1Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 -US20070099885A1,8,OCc1cc(Br)ccc1Cl>>O=Cc1cc(Br)ccc1Cl -US20040138269A1,2,CCOC(=O)c1[nH]c(C)c(-c2ccc(C(=O)O)cc2)c1C.N#Cc1ccc(N)cc1>>CCOC(=O)c1[nH]c(C)c(-c2ccc(C(=O)Nc3ccc(C#N)cc3)cc2)c1C -US08569535B2,6,CCOC(=O)C1(NC(=O)c2c(C)cc(C)nc2N(C)CC)Cc2ccccc2C1>>CCN(C)c1nc(C)cc(C)c1C(=O)NC1(C(=O)O)Cc2ccccc2C1 -US04585772,1,C=CCBr.O=C1Nc2ccc(C(F)(F)F)cc2C2=NCCCN12>>C=CCN1C(=O)N2CCCN=C2c2cc(C(F)(F)F)ccc21 -US20100324010A1,2,C1COCCN1.CC(C)CN(C(=O)c1cnc(C(C)(C)C)nc1NCc1ncco1)[C@H]1C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C1>>CC(C)CN(C(=O)c1cnc(C(C)(C)C)nc1NCc1ncco1)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1 -US20080269193A1,4,CC(=O)OCC(=O)C1C(=O)CC(C)(C)CC1=O.N#Cc1ccc(NN)cc1NC1CCC(O)CC1>>CC(=O)OCc1nn(-c2ccc(C#N)c(NC3CCC(O)CC3)c2)c2c1C(=O)CC(C)(C)C2 -US20070185155A1,1,BrCCCOc1ccccc1.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C12CCN(CC1)CC2>>OC(c1ccc(F)cc1)(c1ccc(F)cc1)C12CC[N+](CCCOc3ccccc3)(CC1)CC2 -US05985922,2,CCCCCCCCCCCCO.C[C@H](NCc1ccccc1O)C(=O)O>>CCCCCCCCCCCCOC(=O)[C@H](C)NCc1ccccc1O -US05817654,9,O=C1Nc2ccc3ccccc3c2CCC1(Cl)Cl>>O=C1Nc2ccc3ccccc3c2CCC1Cl -US07326791B2,2,Cc1cc(C(=O)O)ccc1C(=O)N1CCCC1.N[C@@H](CCc1nnn[nH]1)c1nc2cc(Cl)ccc2[nH]1>>Cc1cc(C(=O)N[C@@H](CCc2nnn[nH]2)c2nc3cc(Cl)ccc3[nH]2)ccc1C(=O)N1CCCC1 -US20070208001A1,7,O=C(O)C1(c2ccc(Cl)cc2)CC1>>OCC1(c2ccc(Cl)cc2)CC1 -US05917038,2,Nc1ccccc1.O=C(O)C#Cc1ccccc1>>O=C(C#Cc1ccccc1)Nc1ccccc1 -US20080153850A1,1,COC(=O)[C@H](C)Cl.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(-c2ccccc2O)ccc1Cl>>COC(=O)[C@@H](C)Oc1ccccc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 -US08546408B2,2,CNOC.O=C(O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>CON(C)C(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20120235084A1,7,O=C(c1ccccc1)c1ccccc1>>OC(c1ccccc1)c1ccccc1 -US20080113983A1,3,CCCC[Sn](CCCC)(CCCC)c1cccs1.O=C(c1ccnc(Br)c1)N1CCOCC1>>O=C(c1ccnc(-c2cccs2)c1)N1CCOCC1 -US06716847B2,1,COc1cc2nccc(Cl)c2cc1OC.COc1ccc(C(=O)Nc2ccc(C)c(N)c2)cc1OC>>COc1ccc(C(=O)Nc2ccc(C)c(Nc3ccnc4cc(OC)c(OC)cc34)c2)cc1OC -US20050033081A1,3,CC(=O)CCc1ccccc1C(F)(F)F.N.[C-]#N>>CC(N)(C#N)CCc1ccccc1C(F)(F)F -US08114873B2,1,CC1CCNCC1.O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1ccnc(Cl)c1>>CC1CCN(c2cc(C(=O)Nc3ccc(OCCN4CCOCC4)c4ccccc34)ccn2)CC1 -US20130261128A1,1,CCc1cc(O)ccc1Cl.COC(=O)C(C)(C)CO>>CCc1cc(OCC(C)(C)C(=O)OC)ccc1Cl -US20050010031A1,6,CCC1CN(C(Cc2ccc3ccccc3c2)C(=O)OC)CCN1C(=O)C(Cc1ccc(F)cc1)NC(=O)OC(C)(C)C>>CCC1CN(C(Cc2ccc3ccccc3c2)C(=O)O)CCN1C(=O)C(Cc1ccc(F)cc1)NC(=O)OC(C)(C)C -US20150031674A1,1,C=CCCBr.CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)[nH]c2n1>>C=CCCn1c(=O)c(-c2ccc(-c3cncc(C)n3)cc2Cl)cc2cnc(SC)nc21 -US07994164B2,1,CC(C)(C)OC(=O)N1C[C@H](Nc2ccc(Br)cc2[N+](=O)[O-])[C@@H](O)C1.O=C(O)CCl>>CC(C)(C)OC(=O)N1C[C@H](Nc2ccc(Br)cc2[N+](=O)[O-])[C@H](OC(=O)CCl)C1 -US06187762B1,9,CC(=O)N[C@H]1[C@@H](Cl)O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O.[N-]=[N+]=[N-]>>CC(=O)N[C@H]1[C@@H](N=[N+]=[N-])O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O -US05674886,1,BrCc1ccc2nonc2c1.O=[N+]([O-])c1ccc(Nn2cncn2)cc1>>O=[N+]([O-])c1ccc(N(Cc2ccc3nonc3c2)n2cncn2)cc1 -US20120071457A1,10,COC(=O)/C(C)=C(/C)C(=O)OC.O=C1CCC(=O)N1Br>>COC(=O)/C(C)=C(/CBr)C(=O)OC -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1N1CCN(C)CC1>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1N1CCN(C)CC1 -US04367229,2,CCOC(=O)c1cnc2n(c1=O)CCC2.NN>>NNC(=O)c1cnc2n(c1=O)CCC2 -US08344144B2,1,CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(N)s2)c(F)c1.Clc1ccc2[nH]nnc2n1>>CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(Nc3ccc4[nH]nnc4n3)s2)c(F)c1 -US20060105458A1,1,COc1ccc2c(C(C)=O)cc(=O)oc2c1.NN>>COc1ccc2c(C(C)=NN)cc(=O)oc2c1 -US20100075953A1,1,CC(C)=O.Fc1cc(OC2CCNCC2)ccc1Br>>CC(C)N1CCC(Oc2ccc(Br)c(F)c2)CC1 -US04447542,7,C=C(C)c1ccc(Br)cc1>>CC(C)c1ccc(Br)cc1 -US05332757,9,CCC1OCC(C)(c2cccc(Sc3ccc(C(C)=O)cc3)c2)O1.NO>>CCC1OCC(C)(c2cccc(Sc3ccc(C(C)=NO)cc3)c2)O1 -US20060058542A1,3,COc1ccc(Cl)cc1.OB(O)c1ccccc1>>COc1ccc(-c2ccccc2)cc1 -US20070179178A1,2,Cc1onc(-c2ccccc2)c1-c1cn2ccc(C(=O)O)cc2n1.NC1CCC1>>Cc1onc(-c2ccccc2)c1-c1cn2ccc(C(=O)NC3CCC3)cc2n1 -US20090143409A1,1,O=C(O)c1cnc(Cl)c(Br)c1.OCC1CC1>>O=C(O)c1cnc(OCC2CC2)c(Br)c1 -US06218429B1,2,CCC(=O)OC(=O)CC.NCCc1c[nH]c2ccc(O)cc12>>CCC(=O)NCCc1c[nH]c2ccc(O)cc12 -US07368578B2,3,COc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1nc(-c2ccco2)oc1C.N#CCC#N>>COc1cc(COc2nn(-c3ccccc3)cc2C=C(C#N)C#N)ccc1OCc1nc(-c2ccco2)oc1C -US07919498B2,1,Cc1ccccc1-c1nc2c(C)cccc2cc1CCl.Nc1ncnc2[nH]nc(I)c12>>Cc1ccccc1-c1nc2c(C)cccc2cc1Cn1nc(I)c2c(N)ncnc21 -US20090318477A1,1,C=CCc1c(Cl)nc(C)nc1Cl.CS(=O)(=O)c1ccc(N)c(F)c1>>C=CCc1c(Cl)nc(C)nc1Nc1ccc(S(C)(=O)=O)cc1F -US20080181866A1,2,CC(C)(C)OC(=O)N1[C@H](c2cccnc2)SC[C@H]1C(=O)O.Nc1nc(-c2ccc(C(=O)NC3CC3)cc2)cs1>>CC(C)(C)OC(=O)N1C(C(=O)Nc2nc(-c3ccc(C(=O)NC4CC4)cc3)cs2)CSC1c1cccnc1 -US07968542B2,2,COC(=O)c1ccc(C(=O)NCc2ccnn2C)s1.NN>>Cn1nccc1CNC(=O)c1ccc(C(=O)NN)s1 -US07432257B2,1,CC(C)(C)OC(=O)N1CCC(Nc2ccc(C#N)cc2Oc2ccccc2Br)CC1>>CC(C)(C)OC(=O)N1CCC(N2c3ccccc3Oc3cc(C#N)ccc32)CC1 -US06465507B2,3,O=C1Cc2cc(S(=O)(=O)N3CCc4cc(Br)ccc43)ccc2N1.O=Cc1[nH]cc2c1CCOC2=O>>O=C1Nc2ccc(S(=O)(=O)N3CCc4cc(Br)ccc43)cc2C1=Cc1[nH]cc2c1CCOC2=O -US20120225904A1,3,Cc1c(F)cc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1.O=c1[nH]nc2cc(I)ccn12>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccn2c(=O)[nH]nc2c1 -US08481574B2,1,CC(C)(C)S(N)=O.CCC(=O)CC>>CCC(CC)=NS(=O)C(C)(C)C -US08138168B1,6,COCCCn1c([C@@H]2CCCN(C(=O)C[C@@H](Cc3ccc(N4CCCC4=O)cc3)NC(=O)OC(C)(C)C)C2)nc2ccccc21>>COCCCn1c([C@@H]2CCCN(C(=O)C[C@H](N)Cc3ccc(N4CCCC4=O)cc3)C2)nc2ccccc21 -US05354759,4,CCSc1nc2c(C)ccnc2n1Cc1ccc(-n2cc(Cl)cc2C#N)cc1.[N-]=[N+]=[N-]>>CCSc1nc2c(C)ccnc2n1Cc1ccc(-n2cc(Cl)cc2-c2nnn[nH]2)cc1 -US03950380,7,CC(C)CCSc1cc(C(=O)O)cc([N+](=O)[O-])c1-c1ccccc1>>CC(C)CCSc1cc(C(=O)O)cc(N)c1-c1ccccc1 -US20130172556A1,6,CCOC(=O)C(=O)C1(CC)C=C(CC)C=C(CC)C1>>CCC1=CC(CC)(C(=O)C(=O)O)CC(CC)=C1 -US08288403B2,1,COc1cc(Br)ccc1-n1cnc(C)c1.Nc1ccn(Cc2ccc(F)cc2)n1>>COc1cc(Nc2ccn(Cc3ccc(F)cc3)n2)ccc1-n1cnc(C)c1 -US20140271662A1,9,N.O=C(O)CC(c1ccc(Cl)cc1)c1ccc(Br)cc1>>NC(=O)CC(c1ccc(Cl)cc1)c1ccc(Br)cc1 -US20030204113A1,2,COc1cccc(CN)c1.COc1cccc(CN=C=S)c1>>COc1cccc(CNC(=S)NCc2cccc(OC)c2)c1 -US20150111877A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cccc(S(=O)(=O)N2CC(N)COc3ncc(NC(=O)C(F)(F)F)cc32)c1>>Cc1cccc(S(=O)(=O)N2CC(NC(=O)OC(C)(C)C)COc3ncc(NC(=O)C(F)(F)F)cc32)c1 -US20080188460A1,7,O=Cc1cnccc1Br>>OCc1cnccc1Br -US20040102437A1,1,O=C1CCC(Nc2ccc3[nH]ncc3c2)CC1.[NH4+]>>NC1CCC(Nc2ccc3[nH]ncc3c2)CC1 -US05464830,2,CC(C)(C)OC(=O)N(CCC(=O)O)Cc1ccco1.NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21>>CC(C)(C)OC(=O)N(CCC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21)Cc1ccco1 -US20080015223A1,2,Cn1ncc(Br)c1N.O=C(Cl)c1ccc(I)cc1>>Cn1ncc(Br)c1NC(=O)c1ccc(I)cc1 -US05547919,1,COC=C(C(=O)OC)c1c(OC)ncnc1Oc1cccc(CBr)c1.N#Cc1ccccc1O>>COC=C(C(=O)OC)c1c(OC)ncnc1Oc1cccc(COc2ccccc2C#N)c1 -US20100056618A1,1,CCI.Oc1ccc(Cc2cc(Br)ccc2F)cc1>>CCOc1ccc(Cc2cc(Br)ccc2F)cc1 -US07087576B2,6,COC(=O)C(Cc1ccc(Oc2ccc(C=C3SC(=O)NC3=O)cc2)cc1)NC(=O)C(CCSC)NC(=O)OC(C)(C)C>>COC(=O)C(Cc1ccc(Oc2ccc(C=C3SC(=O)NC3=O)cc2)cc1)NC(=O)C(N)CCSC -US20020091148A1,4,CCOC(=O)C(=O)CCc1ccccc1.NNc1ccccc1>>CCOC(=O)c1[nH]c2ccccc2c1Cc1ccccc1 -US20110207701A1,7,O=[N+]([O-])c1cccc2c1B(O)OC2>>Nc1cccc2c1B(O)OC2 -US20060264460A1,1,N#Cc1cnc2c(Br)cc([N+](=O)[O-])cc2c1Cl.NC1CCCCCC1>>N#Cc1cnc2c(Br)cc([N+](=O)[O-])cc2c1NC1CCCCCC1 -US20050130989A1,6,Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)n(-c2ccccc2)n1>>Cc1cc(C(=O)N2CCNCC2)n(-c2ccccc2)n1 -US20140243374A1,2,CC1CCCCC1N(Cc1ccc(C(=O)O)cc1)S(=O)(=O)c1ccc(Cl)cc1.C[C@@H](N)CO>>CC1CCCCC1N(Cc1ccc(C(=O)N[C@H](C)CO)cc1)S(=O)(=O)c1ccc(Cl)cc1 -US08399436B2,6,O=C1c2ccccc2C(=O)N1c1ccn(Cc2ccc(Cl)cc2C(F)(F)F)n1>>Nc1ccn(Cc2ccc(Cl)cc2C(F)(F)F)n1 -US20100130538A1,2,Cc1cc2c([C@@H]3C[C@H]3CN)cccn2n1.O=C(Cl)C1CC1>>Cc1cc2c([C@@H]3C[C@H]3CNC(=O)C3CC3)cccn2n1 -US20130012491A1,3,Brc1cnc(I)nc1.CC(C)Oc1ccc(B2OC(C)(C)C(C)(C)O2)cc1Cl>>CC(C)Oc1ccc(-c2ncc(Br)cn2)cc1Cl -US20110136763A1,6,COc1cc(Oc2ccccc2)cc(C)c1C=O>>Cc1cc(Oc2ccccc2)cc(O)c1C=O -US20140249139A1,6,CCOC(=O)c1cc(F)cc(-c2ncnc3ccc(Br)cc23)c1>>O=C(O)c1cc(F)cc(-c2ncnc3ccc(Br)cc23)c1 -US07615552B2,1,C1COCCN1.COc1cc2nc(Cl)nc(N)c2cc1OC>>COc1cc2nc(N3CCOCC3)nc(N)c2cc1OC -US20140187553A1,3,CC1(C)OB(c2ccccc2F)OC1(C)C.Cc1ccc(S(=O)(=O)n2cc(I)c3cc(-c4nnc(S(C)(=O)=O)s4)ccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3ccccc3F)c3cc(-c4nnc(S(C)(=O)=O)s4)ccc32)cc1 -US20080255202A1,1,CC(C)(C)OC(=O)C(C)(C)Sc1ccc(CNCc2ccco2)cc1.Fc1ccc(Cc2noc(CCl)n2)cc1>>CC(C)(C)OC(=O)C(C)(C)Sc1ccc(CN(Cc2ccco2)Cc2nc(Cc3ccc(F)cc3)no2)cc1 -US20130190347A1,9,CCOC(=O)CCn1c2c(c3cc(C)ccc31)CN(C)CC2.N>>Cc1ccc2c(c1)c1c(n2CCC(N)=O)CCN(C)C1 -US20120065202A1,2,CC(C)(C)C(=O)Cl.CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CCNC3)cc1>>CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CCN(C(=O)C(C)(C)C)C3)cc1 -US20110172230A1,6,CC(C)(C)OC(=O)N1CCN(Cc2ccc(OCc3cccc(F)c3)cc2)CC1>>Fc1cccc(COc2ccc(CN3CCNCC3)cc2)c1 -US20060160832A1,7,O=c1ccc2c(Oc3ccc([N+](=O)[O-])cc3)ccnc2[nH]1>>Nc1ccc(Oc2ccnc3[nH]c(=O)ccc23)cc1 -US20110098296A1,1,CCc1nc(-c2cccc(NC(=O)c3c(F)cccc3F)c2)c(-c2ccnc(Cl)n2)s1.Nc1ccc(N2CCC(N3CCCCC3)CC2)c(F)c1>>CCc1nc(-c2cccc(NC(=O)c3c(F)cccc3F)c2)c(-c2ccnc(Nc3ccc(N4CCC(N5CCCCC5)CC4)c(F)c3)n2)s1 -US20080194571A1,3,C#C[C@H]1CC[C@H]2CN(c3nccnc3C#N)CCN12.COc1cccc(I)n1>>COc1cccc(C#C[C@H]2CC[C@H]3CN(c4nccnc4C#N)CCN23)n1 -US20070287725A1,7,CC(C)(C)OC(=O)NCCNc1c([N+](=O)[O-])c(Cl)nc2ccccc12>>CC(C)(C)OC(=O)NCCNc1c(N)c(Cl)nc2ccccc12 -US04761420,1,COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1.COCCOCCl>>COCCOCN1C(C)=C(C(=O)OC)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OC)=C1C -US20130190307A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.NNc1cnc2ccc(Br)cc2n1>>CC(C)(C)OC(=O)N1CCC(C(=O)NNc2cnc3ccc(Br)cc3n2)CC1 -US20150175561A1,9,C#CC[C@H](NC(=O)OC(C)(C)C)C(=O)O.N>>C#CC[C@H](NC(=O)OC(C)(C)C)C(N)=O -US08952151B2,1,COC(=O)c1ccncc1Br.NCc1ccc(C(F)(F)F)cc1>>COC(=O)c1ccncc1NCc1ccc(C(F)(F)F)cc1 -US20130184222A1,3,CC1OB(c2cnn(C)c2)OC1C.Nc1cccc(Br)c1>>Cn1cc(-c2cccc(N)c2)cn1 -US20100063041A1,1,CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC.Cc1cc(Br)oc1CO>>CCOC(=O)[C@H](Cc1ccc(OCc2oc(Br)cc2C)cc1)OCC -US20110200549A1,1,CCCCCI.NCc1ccccc1>>CCCCCNCc1ccccc1 -US20150274777A1,6,COc1ccc(C[C@H](NC(=O)C2(NC(=O)C3Cc4ccccc4C3)CC2)C(=O)OCc2ccccc2)cc1>>COc1ccc(C[C@H](NC(=O)C2(NC(=O)C3Cc4ccccc4C3)CC2)C(=O)O)cc1 -US20050096380A1,7,CCOC(=O)/C(F)=C(/C)c1cc2c(cc1OC)OC(C)(C)C=C2CC>>CCC1=CC(C)(C)Oc2cc(OC)c(/C(C)=C(/F)CO)cc21 -US04562192,2,O=C(Cl)C12CC3CC(CC(C3)C1)C2.OCCc1c(-c2ccccc2)n2nnnc2n2ncnc12>>O=C(OCCc1c(-c2ccccc2)n2nnnc2n2ncnc12)C12CC3CC(CC(C3)C1)C2 -US07943609B2,6,C[C@H]1COCc2nc3c(N)nc4cc(OCc5ccccc5)ccc4c3n21>>C[C@H]1COCc2nc3c(N)nc4cc(O)ccc4c3n21 -US08614206B2,1,CC(C)(C)OC(=O)N1CCNC(=O)CC1.Cn1ncc([N+](=O)[O-])c1Br>>Cn1ncc([N+](=O)[O-])c1N1CCN(C(=O)OC(C)(C)C)CCC1=O -US20100130738A1,6,COc1ccc(C2=NNC(=O)C2(C)C)c(F)c1F>>CC1(C)C(=O)NN=C1c1ccc(O)c(F)c1F -US20110183954A1,1,Cn1cnc(Nc2nc(Cl)nc(Cl)n2)c1.NC(c1ccc(F)cc1)C1CCCC1>>Cn1cnc(Nc2nc(Cl)nc(NC(c3ccc(F)cc3)C3CCCC3)n2)c1 -US08404731B2,3,O=C1CN(c2cccc(-n3cc(-c4ccc(Cl)cc4Cl)nc3Cc3ccc(I)cc3)c2)S(=O)(=O)N1.OB(O)c1ccc(Br)cc1>>O=C1CN(c2cccc(-n3cc(-c4ccc(Cl)cc4Cl)nc3Cc3ccc(-c4ccc(Br)cc4)cc3)c2)S(=O)(=O)N1 -US20090105219A1,2,C1CCNC1.O=C(O)CC12CC(=O)Nc3cccc(c31)N(Cc1ccc3cc4c(cc3n1)C[C@]1(C4)C(=O)Nc3ncccc31)C2>>O=C1CC2(CC(=O)N3CCCC3)CN(Cc3ccc4cc5c(cc4n3)C[C@]3(C5)C(=O)Nc4ncccc43)c3cccc(c32)N1 -US08383644B2,6,COC(=O)[C@H](Cc1ccc(-c2ccnc(C)c2C)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1C(=O)c1nc(C)oc1C)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)CO3>>Cc1nc(C(=O)N2Cc3cc4c(cc3C[C@H]2C(=O)N[C@@H](Cc2ccc(-c3ccnc(C)c3C)cc2)C(=O)O)OC[C@H](c2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)O4)c(C)o1 -US20040138223A1,1,CC(C)c1ccc(N(Cc2cn[nH]c2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1.ClCc1cccnc1>>CC(C)c1ccc(N(Cc2cnn(Cc3cccnc3)c2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1 -US03980681,8,CC(=O)Oc1ccc2c(c1)CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)C[C@H](O)[C@]21O>>CC(=O)Oc1ccc2c(c1)CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC(=O)[C@]21O -US05736539,6,CCCC[C@H]1CN(Cc2ccccc2)CCN1C(=O)c1cccc(C)c1C>>CCCC[C@H]1CNCCN1C(=O)c1cccc(C)c1C -US20070191372A1,2,CN(CCCN)CCCNc1n[n+]([O-])c2ccccc2[n+]1[O-].Cc1cccc2cc3cccc(C(=O)O)c3nc12>>Cc1cccc2cc3cccc(C(=O)NCCCN(C)CCCNc4n[n+]([O-])c5ccccc5[n+]4[O-])c3nc12 -US05547972,1,C=O.CC(C)(NCCCn1ccnc1)c1ccc(Cl)cc1>>CN(CCCn1ccnc1)C(C)(C)c1ccc(Cl)cc1 -US05393759,4,CCC(=O)CCN1CCN(C)CC1.COc1ccc(CCO)cc1OC>>CCC1(CCN2CCN(C)CC2)OCCc2cc(OC)c(OC)cc21 -US06172066B2,2,CCC1=C(C(=O)OCc2ccccc2)C(c2ccc(F)cc2F)NC(OC)=N1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCC1=C(C(=O)OCc2ccccc2)C(c2ccc(F)cc2F)N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C(OC)=N1 -US20100240644A1,7,COCCC(=O)c1cn(C)c2ccc(CNC3CC3)cc12>>COCCCc1cn(C)c2ccc(CNC3CC3)cc12 -US20140323390A1,2,CCCCCCCCCCCC(=O)Cl.CCCCCCCCCCCCOC[C@@H](O)CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C>>CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C)OC(=O)CCCCCCCCCCC -US20100048537A1,1,CN1CCC(O)c2ccoc2C1.Fc1ccc2ccccc2c1>>CN1CCC(Oc2ccc3ccccc3c2)c2ccoc2C1 -US20090275598A1,6,CCOC(=O)CC(c1ccc(OC2Cc3ccccc3C2)cc1)c1cc(F)cc(F)c1>>O=C(O)CC(c1ccc(OC2Cc3ccccc3C2)cc1)c1cc(F)cc(F)c1 -US07692017B2,1,COc1ccc(C=O)c(OC)c1.COc1ccc(N)c(C(=O)c2cccc(F)c2)c1>>COc1ccc(CNc2ccc(OC)cc2C(=O)c2cccc(F)c2)c(OC)c1 -US20080146731A1,1,CCN(CCO)c1ccccc1.O=C(c1ccccc1)c1ccc(CBr)cc1>>CCN(CCOCc1ccc(C(=O)c2ccccc2)cc1)c1ccccc1 -US09018214B2,6,C[C@@H]1CN(Cc2ccccc2)[C@@H](CN2CCOCC2)CN1C(=O)OC(C)(C)C>>C[C@@H]1CN[C@@H](CN2CCOCC2)CN1C(=O)OC(C)(C)C -US20130150340A1,2,CC(C)(C)OC(=O)N[C@@H]1CCNC1.O=C(O)c1cc(-c2ccc(O)cc2)nc2[nH]ncc12>>CC(C)(C)OC(=O)N[C@@H]1CCN(C(=O)c2cc(-c3ccc(O)cc3)nc3[nH]ncc23)C1 -US05298652,1,BrCc1ccccc1.CCCCCCCCCCCCCCCCCCOc1ccc(O)c(C(=O)OC)c1>>CCCCCCCCCCCCCCCCCCOc1ccc(OCc2ccccc2)c(C(=O)OC)c1 -US20110135671A1,1,CC(C)(C)N1CCNCC1.CCCCOc1nc(N)c2nc(OC)n(CCCCCCCl)c2n1>>CCCCOc1nc(N)c2nc(OC)n(CCCCCCN3CCN(C(C)(C)C)CC3)c2n1 -US20070293521A1,1,C=CCN.Fc1cnc(Cl)nc1Nc1ccc2c(c1)OCCO2>>C=CCNc1ncc(F)c(Nc2ccc3c(c2)OCCO3)n1 -US08263785B2,1,CCOP(C)(=O)C(C(N)=O)c1csc2ccc(Cl)cc12.Fc1ccc(C=CBr)cc1F>>CCOP(C)(=O)C(C(=O)NC=Cc1ccc(F)c(F)c1)c1csc2ccc(Cl)cc12 -US20150210682A1,6,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCC(C)(C)CO)cc1CC2C(C)C>>COc1cc2c(cc1OCC(C)(C)CO)CC(C(C)C)n1cc(C(=O)O)c(=O)cc1-2 -US20050239836A1,3,C#C[Si](C)(C)C.COC(=O)C1(c2cc(Br)sc2Br)CCCCC1>>COC(=O)C1(c2cc(C#C[Si](C)(C)C)sc2Br)CCCCC1 -US05998665,1,CN.CNc1nc(Cl)cc(NS(=O)(=O)c2cccc(Cl)c2)n1>>CNc1cc(NS(=O)(=O)c2cccc(Cl)c2)nc(NC)n1 -US20030069266A1,1,C[O-].Clc1ncc(Br)c2cc[nH]c12>>COc1cnc(Cl)c2[nH]ccc12 -US20140010783A1,9,CNS(=O)(=O)c1ccc(N)cc1.S=C(Cl)Cl>>CNS(=O)(=O)c1ccc(N=C=S)cc1 -US04011342,2,CN=C=S.Nc1c(Cl)cccc1Cl>>CNC(=S)Nc1c(Cl)cccc1Cl -US20140213599A1,1,CN1c2cc(Cl)nc(=O)n2CC1(C)C.OCc1ccc(Oc2ccc(C(F)(F)F)nc2)c(F)c1>>CN1c2cc(OCc3ccc(Oc4ccc(C(F)(F)F)nc4)c(F)c3)nc(=O)n2CC1(C)C -US05691330,2,Cc1sc2c(c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCNC2.O=C(Cl)c1ccccc1>>Cc1sc2c(c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCN(C(=O)c1ccccc1)C2 -US08178522B2,2,CCCCc1noc(C)c1CCc1nc(C)c(C(=O)O)s1.NC1CCOC1>>CCCCc1noc(C)c1CCc1nc(C)c(C(=O)NC2CCOC2)s1 -US08222402B2,1,CCOC(=O)CN1CCC(=O)CC1.c1ccc(CN2CCNCC2)cc1>>CCOC(=O)CN1CCC(N2CCN(Cc3ccccc3)CC2)CC1 -US05880130,1,CN(C)CCCCl.Cc1cccc(Nc2cc(Nc3cccc(O)c3)ncn2)c1>>Cc1cccc(Nc2cc(Nc3cccc(OCCCN(C)C)c3)ncn2)c1 -US20060079548A1,6,CNC(=O)c1cn(C)c2cc(OC)ccc12>>CNC(=O)c1cn(C)c2cc(O)ccc12 -US07507740B2,6,CCOC(=O)c1cc(Nc2ncnc3cc[nH]c23)ccc1Oc1ccccc1>>O=C(O)c1cc(Nc2ncnc3cc[nH]c23)ccc1Oc1ccccc1 -US06407094B1,1,CC(C)(C)OC(=O)CBr.CC(C)(C)OC(=O)Nc1cc(O)c(I)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)COc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1I -US08962663B2,2,CCCCCCCCc1ccc(S(=O)(=O)Cl)cc1.Nc1nncs1>>CCCCCCCCc1ccc(S(=O)(=O)Nc2nncs2)cc1 -US06444672B1,6,CCOC(=O)CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc(OC)cc1)C(=O)OCc1ccccc1>>CCOC(=O)CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc(OC)cc1)C(=O)O -US20110257242A1,1,CC(C)Br.COC1(c2cc(F)cc(F)c2)CCNC1>>COC1(c2cc(F)cc(F)c2)CCN(C(C)C)C1 -US05602277,6,COC(=O)Nc1ccc(C(=O)OC)cc1>>COC(=O)Nc1ccc(C(=O)O)cc1 -US20100056527A1,7,COC(=O)c1cc(Cl)cc2cc(-c3ccc(Cl)cc3Cl)oc12>>OCc1cc(Cl)cc2cc(-c3ccc(Cl)cc3Cl)oc12 -US04656298,7,CCOC(OCC)P(=O)(CC(C[N+](=O)[O-])c1ccc(Cl)cc1)OCC>>CCOC(OCC)P(=O)(CC(CN)c1ccc(Cl)cc1)OCC -US20130245262A1,1,C=O.Cc1c2ccc(N)cc2nn1C>>CNc1ccc2c(C)n(C)nc2c1 -US20040157866A1,6,CCOC(=O)c1c(-c2ccc(C(F)(F)F)cc2)cc(C)nc1C>>Cc1cc(-c2ccc(C(F)(F)F)cc2)c(C(=O)O)c(C)n1 -US20100286442A1,9,CCOC(=O)C[C@@H](CBr)CC(C)C.[N-]=[N+]=[N-]>>CCOC(=O)C[C@@H](CN=[N+]=[N-])CC(C)C -US06638929B2,1,N#Cc1cnc2c(c1Cl)C=C1N=CN=C1C2.Nc1ccc(Cl)cc1Br>>N#Cc1cnc2c(c1Nc1ccc(Cl)cc1Br)C=C1N=CN=C1C2 -US04119710,7,Nc1c(Br)cc(C(=O)CNC2CC2)cc1C(F)(F)F>>Nc1c(Br)cc(C(O)CNC2CC2)cc1C(F)(F)F -US20150030744A1,1,C=C(C)[C@@H]1CC[C@@H](C)C[C@H]1O.O=C(O)CCl>>C=C(C)[C@@H]1CC[C@@H](C)C[C@H]1OCC(=O)O -US20110059951A1,2,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.N#Cc1ccc(C(=O)O)c(F)c1>>C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1ccc(C#N)cc1F -US20060116410A1,2,COc1cccc(C(=O)O)c1.N#Cc1ccc(CN)c(O)c1>>COc1cccc(C(=O)NCc2ccc(C#N)cc2O)c1 -US20130150339A1,3,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(Cl)nccc3c2)c(OC)c1.OB(O)c1ccc(C(F)(F)F)cc1F>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4F)nccc3c2)c(OC)c1 -US20030078251A1,1,CCCI.CCOC(=O)c1oc2ccc([N+](=O)[O-])cc2c1O>>CCCOc1c(C(=O)OCC)oc2ccc([N+](=O)[O-])cc12 -US20070249670A1,7,COC(=O)[C@](C)(NC(=O)c1ccc(F)cc1[N+](=O)[O-])C1CCCCC1>>COC(=O)[C@](C)(NC(=O)c1ccc(F)cc1N)C1CCCCC1 -US20040225009A1,6,COc1ccc(CN2C(=O)[C@@H](OC(C)=O)[C@H]2C(C)C)cc1>>CC(=O)O[C@@H]1C(=O)N[C@@H]1C(C)C -US08481550B2,7,CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](Nc2c(Cl)cnc(N)c2[N+](=O)[O-])C[C@@H]1O[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](Nc2c(Cl)cnc(N)c2N)C[C@@H]1O[Si](C)(C)C(C)(C)C -US20110312938A1,3,COC(=O)CN=[N+]=[N-].COc1ccncc1C=O>>COC(=O)/C(=C/c1cnccc1OC)N=[N+]=[N-] -US20070249670A1,2,COC(=O)[C@@H](N)C1CCCCC1.Cc1cccc(C)c1NC(=O)Nc1cc(Cl)ccc1C(=O)O>>COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1NC(=O)Nc1c(C)cccc1C)C1CCCCC1 -US20110263567A1,3,O=Cc1c(Br)ccc2c1OCO2.OB(O)c1ccccc1Br>>O=Cc1c(-c2ccccc2Br)ccc2c1OCO2 -US20150183763A1,3,CC1(C)OB(c2cccc(COCC(F)(F)F)c2)OC1(C)C.Nc1cc(I)n(-c2ccccc2)n1>>Nc1cc(-c2cccc(COCC(F)(F)F)c2)n(-c2ccccc2)n1 -US05883098,1,ClCc1cccnc1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCNC[C@H]1Cc1ccccc1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(Cc2cccnc2)C[C@H]1Cc1ccccc1 -US08198271B2,6,CN(C)CCC(NC(=O)Nc1ccc2c(c1)CCC2)c1ccc(C(=O)OCc2ccccc2)cc1>>CN(C)CCC(NC(=O)Nc1ccc2c(c1)CCC2)c1ccc(C(=O)O)cc1 -US08071605B2,2,COC(=O)N1CC[C@@H](N)[C@@H](C)C1.Cc1[nH]c(C(=O)O)cc1Cl>>COC(=O)N1CC[C@@H](NC(=O)c2cc(Cl)c(C)[nH]2)[C@@H](C)C1 -US20100099718A1,3,CCCC[Sn](CCCC)(CCCC)COC.COC(=O)c1ccc(Cl)nc1N>>COCc1ccc(C(=O)OC)c(N)n1 -US08022248B2,1,CS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1.O=C(O)CCc1ccc(Cl)cc1O>>CS(=O)(=O)c1ccc(Oc2cc(Cl)ccc2CCC(=O)O)c(C(F)(F)F)c1 -US08293734B2,6,CC(C)(C)[Si](C)(C)OCC(COc1ccc(Br)nc1)Cn1cc([N+](=O)[O-])nc1Br>>O=[N+]([O-])c1cn(CC(CO)COc2ccc(Br)nc2)c(Br)n1 -US20100075952A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCC1)CCC2.O=C1Cc2cc(F)cc(Br)c2N1>>Cc1c(C=C2C(=O)Nc3c(Br)cc(F)cc32)[nH]c2c1C(=O)N(CCN1CCCC1)CCC2 -US04599344,7,CCCCCCC[N+]12CCC(CC1)C(=CCc1ccc(Cl)cc1)C2>>CCCCCCC[N+]12CCC(CC1)C(CCc1ccc(Cl)cc1)C2 -US07985744B2,1,CC(C)(C)OC(=O)CBr.C[C@@H](O)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>C[C@@H](OCC(=O)OC(C)(C)C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C -US08906946B2,1,O=Cc1cccs1.[NH3+]CCOc1ccc2ccccc2c1F>>Fc1c(OCCNCc2cccs2)ccc2ccccc12 -US06391891B1,3,CC(=O)Nc1ccc(Br)c(Cl)c1Cl.OB(O)c1ccncc1>>CC(=O)Nc1ccc(-c2ccncc2)c(Cl)c1Cl -US04777172,6,COCc1ncnc(N2CCCCC2)c1C>>Cc1c(CO)ncnc1N1CCCCC1 -US07494997B2,2,CCO.Cc1ccc(C(=O)O)cc1Br>>CCOC(=O)c1ccc(C)c(Br)c1 -US20120184736A1,1,Cc1cccc(C2CC2)c1O.Oc1cc(Cl)nnc1Cl>>Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O -US20040106657A1,1,CCOC(=O)C(Cc1cccc2[nH]ccc12)OCC.Cc1oc(-c2ccc(C(C)C)cc2)nc1CCl>>CCOC(=O)C(Cc1cccc2c1ccn2Cc1nc(-c2ccc(C(C)C)cc2)oc1C)OCC -US07297795B2,2,COc1cc(N)c(Cl)cc1Cl.N#CCC(=O)O>>COc1cc(NC(=O)CC#N)c(Cl)cc1Cl -US05414142,1,ClCc1ccccc1.OC1CCCCCCCCCCC1>>c1ccc(COC2CCCCCCCCCCC2)cc1 -US20120252761A1,3,CCS(=O)(=O)c1cccc(B(O)O)c1.Cc1cnc(F)c(-c2c(Cl)cc(C(F)(F)F)c(C)c2[N+](=O)[O-])c1>>CCS(=O)(=O)c1cccc(-c2cc(C(F)(F)F)c(C)c([N+](=O)[O-])c2-c2cc(C)cnc2F)c1 -US07871752B2,1,COC(=O)C1C2CC3C(OC(=O)C31)C2O.O=C(O)CCl>>COC(=O)C1C2CC3C(OC(=O)C31)C2OC(=O)CCl -US04122265,2,CS(=O)(=O)Cl.O=C(OCCCO)c1[nH]c(-c2ccccc2)c2cc(Cl)ccc12>>CS(=O)(=O)OCCCOC(=O)c1[nH]c(-c2ccccc2)c2cc(Cl)ccc12 -US20050245518A1,6,CC(C)(C)[Si](C)(C)OCCN(CCc1c[nH]c2ccccc12)Cc1ccc(C=CC(=O)Nc2ccccc2N)cc1>>Nc1ccccc1NC(=O)C=Cc1ccc(CN(CCO)CCc2c[nH]c3ccccc23)cc1 -US20060014790A1,1,CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(Br)c2)CCC2(CC1)OCCO2.c1cn[nH]c1>>CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(-n3cccn3)c2)CCC2(CC1)OCCO2 -US20120172376A1,3,CC1(C)OB(C2=CCOCC2)OC1(C)C.O=C(Nc1cccc(I)n1)Nc1ccnc2c(F)cccc12>>O=C(Nc1cccc(C2=CCOCC2)n1)Nc1ccnc2c(F)cccc12 -US20130210880A1,7,N#Cc1ccc2c(c1)C(Cc1ccccc1)NC2=O>>NCc1ccc2c(c1)C(Cc1ccccc1)NC2=O -US20140323463A1,3,CN1CCN(c2ccc(Nc3nc(Oc4cccc([N+](=O)[O-])c4)cnc3C(N)=O)cc2Br)CC1.OB(O)c1ccncc1>>CN1CCN(c2ccc(Nc3nc(Oc4cccc([N+](=O)[O-])c4)cnc3C(N)=O)cc2-c2ccncc2)CC1 -US08247556B2,1,NCc1ccnc2[nH]ccc12.O=C(Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1cccnc1F>>O=C(Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1cccnc1NCc1ccnc2[nH]ccc12 -US20030065180A1,1,CNC.N#Cc1cnc2cc3c(cc2c1Nc1ccc(F)c(Cl)c1)N(CCCCCl)CCO3>>CN(C)CCCCN1CCOc2cc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3cc21 -US20150105367A1,1,CC(C)(O)CCN(Cc1ccccc1)Cc1ccccc1.CI>>COC(C)(C)CCN(Cc1ccccc1)Cc1ccccc1 -US20110166137A1,6,CNc1nccc(-c2cc(NC3CCN(C(=O)OCC4c5ccccc5-c5ccccc54)CC3)c3cc(OC)ccc3c2)n1>>CNc1nccc(-c2cc(NC3CCN(C(=O)OCC4c5ccccc5-c5ccccc54)CC3)c3cc(O)ccc3c2)n1 -US20040058995A1,2,C/C(=C\CO)CCC[C@H](C)CCC[C@H](C)CCCC(C)C.CCCCCCCCCC=CC=CC=CC=CC=CC(=O)O>>CCCCCCCCCC=CC=CC=CC=CC=CC(=O)OC/C=C(\C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C -US20080188528A1,6,COC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)c1cccn(Cc2ccccc2Cl)c1=O>>CC(C)(C)OC(=O)NCCC[C@H](NC(=O)c1cccn(Cc2ccccc2Cl)c1=O)C(=O)O -US07795254B2,6,COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3cc(CO[Si](C)(C)C(C)(C)C)on3)c2cc1OC>>COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3cc(CO)on3)c2cc1OC -US05750704,1,ClCc1ccc(Cl)nc1.O=[N+]([O-])C=C1NCCS1>>O=[N+]([O-])C=C1SCCN1Cc1ccc(Cl)nc1 -US20090275598A1,3,CC#C[C@H](CC(=O)OC)c1ccc(OC2CCc3cc(Br)ccc32)cc1.CCOc1cccc(B(O)O)c1>>CC#C[C@H](CC(=O)OC)c1ccc(OC2CCc3cc(-c4cccc(OCC)c4)ccc32)cc1 -US08003785B2,2,CC(C)(C)OC(=O)N1CCC(N)CC1.COc1cc(C(=O)O)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US08486953B2,2,COC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c2c1C.COCCN>>COCCNC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c2c1C -US20110212918A1,2,CC(=O)OC(C)=O.CCc1cc(N)cnc1SCc1ccccc1>>CCc1cc(NC(C)=O)cnc1SCc1ccccc1 -US07381738B2,2,CC(=O)OCC1C(N)CC2CN(C(=O)OC(C)(C)C)CC21.O=C(O)CNC(=O)OCc1ccccc1>>CC(=O)OCC1C(NC(=O)CNC(=O)OCc2ccccc2)CC2CN(C(=O)OC(C)(C)C)CC21 -US20040034034A1,2,CC(=O)OC(C)(C)C(=O)Cl.C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1S(N)(=O)=O>>CC(=O)OC(C)(C)C(=O)NS(=O)(=O)c1cc(Cl)ccc1OCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C -US20060122181A1,3,O=Cc1cc(Br)cs1.OCc1ccc(B(O)O)cc1>>O=Cc1cc(-c2ccc(CO)cc2)cs1 -US20100029678A1,2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=C(O[C@@H]1CO[C@@H]2[C@H](O)CO[C@H]12)N1CCC(O[N+](=O)[O-])CC1>>O=C(Oc1ccc([N+](=O)[O-])cc1)O[C@@H]1CO[C@@H]2[C@H](OC(=O)N3CCC(O[N+](=O)[O-])CC3)CO[C@H]12 -US05162367,6,CCOC(=O)C=C(C)C=CCCCCCCOCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(/C=C/CCCCCCOCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)=C\C(=O)O -US07560558B2,1,CCOC(=O)C1CCNCC1.COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCl>>CCOC(=O)C1CCN(CCOc2cc3nccc(Oc4cc5ccccc5nc4C)c3cc2OC)CC1 -US05194617,3,CC(=O)Oc1c(C)c(CI)nc2ccc(F)cc12.CCCCCC/C=C/I>>CCCCCC/C=C/Cc1nc2ccc(F)cc2c(OC(C)=O)c1C -US20030162777A1,7,O=C(O)c1ccc2c(Cl)cccc2n1>>O=C(O)C1CCc2c(Cl)cccc2N1 -US20120094992A1,1,CC1Oc2c(Cc3ccccc3)cc(C=O)cc2NC1=O.CNC(=O)c1ccc(N2CCNCC2)cc1>>CNC(=O)c1ccc(N2CCN(Cc3cc(Cc4ccccc4)c4c(c3)NC(=O)C(C)O4)CC2)cc1 -US05712300,2,C=C(C)C1(CC(C)C)CCN(CC(=O)OCC)C1=O.CN>>C=C(C)C1(CC(C)C)CCN(CC(=O)NC)C1=O -US20080194535A1,2,C=CCCCC(=O)O.C=CCO[C@@H]1C[C@H](NC[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)c2cc(Br)ccc21>>C=CCCCC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CN[C@@H]1C[C@@H](OCC=C)c2ccc(Br)cc21 -US20120258950A1,3,CC(C)(COC1CCCCO1)n1cc(I)c2cnc(Cl)nc21.CON(C)C(=O)c1cncc(Br)c1>>CC(C)(COC1CCCCO1)n1cc(C(=O)c2cncc(Br)c2)c2cnc(Cl)nc21 -US20140031345A1,6,CC(C)(C)OC(=O)N1CCC(c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)CC1>>c1ccc(-c2cccc3nc(C4CCNCC4)nc(NCc4ccccn4)c23)cc1 -US05374764,1,CS(=O)(=O)Nc1cc([N+](=O)[O-])ccc1F.OC1CCCCC1>>CS(=O)(=O)Nc1cc([N+](=O)[O-])ccc1OC1CCCCC1 -US20070155763A1,1,CC(C)OCCOc1ccc(O)c(F)c1.Cc1c(Cl)ncnc1OC1CCN(C(=O)OC(C)C)CC1>>Cc1c(Oc2ccc(OCCOC(C)C)cc2F)ncnc1OC1CCN(C(=O)OC(C)C)CC1 -US20080214548A1,3,CC(C)(C)OC(=O)NCCc1ccc(Br)cc1.OB(O)c1cccc(O)c1>>CC(C)(C)OC(=O)NCCc1ccc(-c2cccc(O)c2)cc1 -US05229400,2,CC(=O)OC(C)=O.Nc1ccc(C=CCN2CCC(=C3c4ccccc4C=Cc4ccccc43)CC2)cc1>>CC(=O)Nc1ccc(C=CCN2CCC(=C3c4ccccc4C=Cc4ccccc43)CC2)cc1 -US20090227575A1,2,CC(=O)Cl.CN(C)CCn1ccc2c3nc(-c4ccc(N)cc4)nc(N4CCOCC4)c3ccc21>>CC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3ccc4c(ccn4CCN(C)C)c3n2)cc1 -US08507690B2,6,CC(=O)Nc1nc(C(=O)Oc2ccc(CCOC(=O)NNC(=O)OC(C)(C)C)cc2)cs1>>CC(=O)Nc1nc(C(=O)Oc2ccc(CCOC(=O)NN)cc2)cs1 -US20040138462A1,1,CI.O=C(NCCc1ccc(S(=O)(=O)c2ccc(O)c(O)c2)cc1)C(F)(F)F>>COc1ccc(S(=O)(=O)c2ccc(CCNC(=O)C(F)(F)F)cc2)cc1O -US20010027193A1,2,CN.O=C(O)C(c1cc(F)cc(F)c1)C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1>>CNC(=O)C(c1cc(F)cc(F)c1)C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1 -US20130005728A1,1,COc1ccccc1[C@@H]1CNC[C@H]1C(=O)O.COc1nc(OS(=O)(=O)C(F)(F)F)cc(N(CCc2ccc(OC(F)(F)F)cc2)C(=O)OC(C)(C)C)n1>>COc1nc(N2C[C@@H](C(=O)O)[C@H](c3ccccc3OC)C2)cc(N(CCc2ccc(OC(F)(F)F)cc2)C(=O)OC(C)(C)C)n1 -US20090253687A1,1,COC(=O)CBr.COC(=O)c1ccc(O)c([N+](=O)[O-])c1>>COC(=O)COc1ccc(C(=O)OC)cc1[N+](=O)[O-] -US04760163,2,CC(C)OC(=O)c1cc(N=C=O)c(F)cc1Cl.CCOC(=O)/C(F)=C(\N)CF>>CCOC(=O)C(F)=C(CF)NC(=O)Nc1cc(C(=O)OC(C)C)c(Cl)cc1F -US08202863B2,7,CNS(=O)(=O)Cc1cccc(C#N)c1>>CNS(=O)(=O)Cc1cccc(CN)c1 -US20130317023A1,2,Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F.O=S(=O)(Cl)c1ccc(Cl)s1>>O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F)c1ccc(Cl)s1 -US20130022629A1,2,Nc1ccncn1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>O=[N+]([O-])c1ccc(S(=O)(=O)Nc2ccncn2)cc1 -US20140322247A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)N[C@@H](c1nc(-c2cc(F)ccc2F)c[nH]1)C1CCOCC1>>CC(C)(C)OC(=O)N[C@@H](c1nc(-c2cc(F)ccc2F)cn1Cc1ccccc1)C1CCOCC1 -US20120101134A1,9,CC(C)Oc1ccc(Br)cc1Cl.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)Oc1ccc(B2OC(C)(C)C(C)(C)O2)cc1Cl -US20100069362A1,7,CCOC(=O)c1ccc(CCNC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)NCCc1ccc(CO)cc1 -US20130338142A1,7,O=[N+]([O-])c1ccc(N2CCN(C3COC3)CC2)cc1>>Nc1ccc(N2CCN(C3COC3)CC2)cc1 -US04831148,7,O=[N+]([O-])c1cc(Cl)cnc1Cl>>Nc1cc(Cl)cnc1Cl -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1ccc2ccc(Cl)cc2c1C=O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3ccc(Cl)cc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US20090143592A1,2,CC(C)(C)c1ccc(NCc2ccc(C(=O)Nc3nn[nH]n3)cc2)cc1.COC(=O)c1cccc(N=C=O)c1>>COC(=O)c1cccc(NC(=O)N(Cc2ccc(C(=O)Nc3nn[nH]n3)cc2)c2ccc(C(C)(C)C)cc2)c1 -US04526896,4,N#CCc1ccc2occ(-c3ccccc3)c2c1.[N-]=[N+]=[N-]>>c1ccc(-c2coc3ccc(Cc4nnn[nH]4)cc23)cc1 -US20060166985A1,6,CC(C)(C)OC(=O)N[C@@H](Cc1cccs1)C(=O)N1CCOCC1>>N[C@@H](Cc1cccs1)C(=O)N1CCOCC1 -US05525612,1,CI.Cc1nc2cnc3ccccc3c2n1CC(C)O>>COC(C)Cn1c(C)nc2cnc3ccccc3c21 -US20080269219A1,1,CCOC(=O)C1CCNCC1.COc1ccccc1OCCCc1oc(Cl)nc1-c1ccc(Cl)cc1>>CCOC(=O)C1CCN(c2nc(-c3ccc(Cl)cc3)c(CCCOc3ccccc3OC)o2)CC1 -US07514470B2,2,CCC(C(=O)O)N(CC1CC1)c1ccc(C#N)c(Cl)c1.CCN>>CCNC(=O)C(CC)N(CC1CC1)c1ccc(C#N)c(Cl)c1 -US20110160202A1,3,CC(C)(C)OC(=O)N1CCC([Zn+])CC1.Fc1nccnc1I>>CC(C)(C)OC(=O)N1CCC(c2nccnc2F)CC1 -US08088784B2,1,CN(C)c1cc(Nc2nc(Cl)ncc2Cl)n[nH]1.C[C@H](N)c1ncc(F)cn1>>C[C@H](Nc1ncc(Cl)c(Nc2cc(N(C)C)[nH]n2)n1)c1ncc(F)cn1 -US06521614B1,2,N#Cc1ccc(N=C=O)cc1.N#Cc1cccc(N)c1>>N#Cc1ccc(NC(=O)Nc2cccc(C#N)c2)cc1 -US20060063779A1,2,CC(N)c1ccccc1.O=C(O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(Cl)c1>>CC(NC(=O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(Cl)c1)c1ccccc1 -US04663331,1,CN(C)CC#CCCl.NCCS>>CN(C)CC#CCSCCN -US20100093728A1,7,O=C(O)c1ccc(Cl)nn1>>OCc1ccc(Cl)nn1 -US07579474B2,1,FCCCBr.OC1(c2cccc(C(F)(F)F)c2F)CCNCC1>>OC1(c2cccc(C(F)(F)F)c2F)CCN(CCCF)CC1 -US20150018422A1,6,CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)c(O)c2)c1)C1CC1>>COc1ccc(F)c(-c2ccc(OCc3cccc(C(CC(=O)O)C4CC4)c3)cc2O)c1 -US04293563,3,CCCCN1C(=O)CNC1=O.O=Cc1cccs1>>CCCCN1C(=O)NC(=Cc2cccs2)C1=O -US20150094302A1,6,CC(=O)OCc1c(-c2cc(Nc3ccc(N4CCN(C5COC5)C[C@@H]4C)cn3)c(=O)n(C)c2)cc(F)cc1-n1ncc2c3c(sc2c1=O)CCCC3>>C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3CO)cn(C)c2=O)nc1 -US20100125064A1,1,CN(C)CCN1CCNCC1.N#CCBr>>CN(C)CCN1CCN(CC#N)CC1 -US20110105535A1,4,CC(=O)C(Br)c1ccnc(Cl)c1.NC(N)=S>>Cc1nc(N)sc1-c1ccnc(Cl)c1 -US08217032B2,3,COc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(OS(=O)(=O)C(F)(F)F)ccc2c1.OB(O)c1ccccc1F>>COc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(-c3ccccc3F)ccc2c1 -US20100216788A1,7,O=[N+]([O-])c1ccc2c(ccn2Cc2cccc(OC(F)(F)F)c2)c1>>Nc1ccc2c(ccn2Cc2cccc(OC(F)(F)F)c2)c1 -US20110021493A1,2,CC(C)N(C)C/C=C/C(=O)O.Clc1ccc(Nc2ncnc3oc4c(c23)CCNC4)cc1Cl>>CC(C)N(C)C/C=C/C(=O)N1CCc2c(oc3ncnc(Nc4ccc(Cl)c(Cl)c4)c23)C1 -US07932272B2,3,CC(C)=O.CCOP(=O)(Cc1cccc(C#N)c1)OCC>>CC(C)=Cc1cccc(C#N)c1 -US20110251225A1,6,C[C@H]1CCCN1C1CCN(C(=O)OC(C)(C)C)CC1>>C[C@H]1CCCN1C1CCNCC1 -US20150018542A1,6,CC(C)(C)OC(=O)N1CCC(NCc2ccc(-c3cc4cc(F)cc(C(N)=O)c4o3)cc2)CC1>>NC(=O)c1cc(F)cc2cc(-c3ccc(CNC4CCNCC4)cc3)oc12 -US05635197,3,CN1C(=O)CC[C@]2(C)c3ccc(Br)cc3CC[C@@H]12.OB(O)c1cccc(C(F)(F)F)c1>>CN1C(=O)CC[C@]2(C)c3ccc(-c4cccc(C(F)(F)F)c4)cc3CC[C@@H]12 -US20090137609A1,3,CCC(CC)(c1ccc(/C=C/C2(O)CCSCC2)c(C)c1)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1.COC(=O)Cc1ccc(Br)cc1>>CCC(CC)(c1ccc(/C=C/C2(O)CCSCC2)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)cc2)c(C)c1 -US08119627B2,1,N#Cc1ccccc1F.Oc1ccc(Cl)cc1Cl>>N#Cc1ccccc1Oc1ccc(Cl)cc1Cl -US20100152183A1,1,CC(C)(C)OC(=O)N1CCN(Cc2c(O)cccc2-c2ccc(Cl)cc2)CC1.CN(C)CCCl>>CN(C)CCOc1cccc(-c2ccc(Cl)cc2)c1CN1CCN(C(=O)OC(C)(C)C)CC1 -US20150093655A1,1,CCBr.CCN(CC)CCO>>CC[N+](CC)(CC)CCO -US05580986,1,COC(=O)c1cc(O)n(C)n1.FC(F)Cl>>COC(=O)c1cc(OC(F)F)n(C)n1 -US04636509,1,N#Cc1ccc(C(=O)CBr)cc1.O=c1ncc(Cl)c[nH]1>>N#Cc1ccc(C(=O)Cn2cc(Cl)cnc2=O)cc1 -US20130237525A1,6,COc1cccc(OC)c1C1CCC(=O)N1Cc1ccc(OCc2ccccc2)cc1>>COc1cccc(OC)c1C1CCC(=O)N1Cc1ccc(O)cc1 -US20100173941A1,1,COCc1ccc(C=O)o1.O=c1[nH]c2ccccc2n1C1CCNCC1>>COCc1ccc(CN2CCC(n3c(=O)[nH]c4ccccc43)CC2)o1 -US20120101086A1,1,Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCNC2.OCCBr>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(CCO)C2 -US05504244,3,CCCCCCCc1ccccc1.N#Cc1ccc(C(=O)Cl)cc1>>CCCCCCCc1ccc(C(=O)c2ccc(C#N)cc2)cc1 -US20120238571A1,1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(Br)cc1CBr.C[S-]>>CSCc1cc(Br)cnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US20090105216A1,1,CN1CCC(N2CCNCC2)CC1.O=[N+]([O-])c1ccc(F)cc1>>CN1CCC(N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)CC1 -US20110039835A1,2,CCOC(=O)N1CCn2c(nc(-c3ccncc3)cc2=O)C(N)C1.COc1ccc(C(=O)O)c(OC)c1>>CCOC(=O)N1CCn2c(nc(-c3ccncc3)cc2=O)C(NC(=O)c2ccc(OC)cc2OC)C1 -US09150555B2,6,CCOC(=O)c1cnn(-c2ncc(Br)cc2Cl)c1C>>Cc1c(C(=O)O)cnn1-c1ncc(Br)cc1Cl -US20050059651A1,7,COC(=O)c1ccc(OC2C=CCCC2)cc1C(=O)OC>>COC(=O)c1ccc(OC2CCCCC2)cc1C(=O)OC -US20150072980A1,3,COc1cc2c(cc1N1CCOCC1)CCC2=O.O=Cc1cc(C(F)(F)F)ccc1F>>COc1cc2c(cc1N1CCOCC1)C/C(=C\c1cc(C(F)(F)F)ccc1F)C2=O -US08247429B2,3,C=CC(=O)OC.COC(=O)c1nc(N(Cc2ccccc2)Cc2ccccc2)ccc1Br>>COC(=O)/C=C/c1ccc(N(Cc2ccccc2)Cc2ccccc2)nc1C(=O)OC -US07557213B2,3,CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O.Cc1cc([Mg+])ccc1Cl>>Cc1cc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)ccc1Cl -US20150141436A1,6,Cc1cc(C2CCC2)[nH]c(=O)c1CNC(=O)OC(C)(C)C>>Cc1cc(C2CCC2)[nH]c(=O)c1CN -US20150158883A1,6,Nc1nc(CCN2C(=O)c3ccccc3C2=O)cs1>>NCCc1csc(N)n1 -US20080306096A1,1,BrCCCBr.Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cc(O)ccc12>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cc(OCCCBr)ccc12 -US20030195356A1,1,Brc1ccncc1.Clc1ccc2[nH]ccc2c1>>Clc1ccc2c(ccn2-c2ccncc2)c1 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](O)c3ccccc3)CC2)c1.O=[N+]([O-])c1ccccc1O>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@@H](Oc3ccccc3[N+](=O)[O-])c3ccccc3)CC2)c1 -US20130296312A1,1,CC(=O)Nc1ccc(Sc2cccn3nc(Cl)nc23)cc1.CC(C)(C)OC(=O)N1CCC(c2ccc(N)cc2)CC1>>CC(=O)Nc1ccc(Sc2cccn3nc(Nc4ccc(C5CCN(C(=O)OC(C)(C)C)CC5)cc4)nc23)cc1 -US08765763B2,6,CC(C)(C)OC(=O)N1C[C@@H](c2cc(F)cc(F)c2)N(CC(=O)Nc2cc3c(cc2Cl)CC2(C3)C(=O)Nc3ncccc32)C(=O)C12COCCOC2>>O=C(CN1C(=O)C2(COCCOC2)NC[C@H]1c1cc(F)cc(F)c1)Nc1cc2c(cc1Cl)CC1(C2)C(=O)Nc2ncccc21 -US20130131018A1,1,CCOc1ccc2c(Cc3cc(OC)c(OC)c(OC)c3)cncc2c1OS(=O)(=O)C(F)(F)F.CNC>>CCOc1ccc2c(Cc3cc(OC)c(OC)c(OC)c3)cncc2c1N(C)C -US20140018393A1,1,CC(C)(C)OC(=O)N1CCC(CC=O)CC1.N[C@@H]1C[C@H]1c1ccccc1>>CC(C)(C)OC(=O)N1CCC(CCN[C@@H]2C[C@H]2c2ccccc2)CC1 -US07144896B2,8,CC(C)(c1cc(-c2ccc(F)c(CO)c2)c2ncccc2c1)S(C)(=O)=O>>CC(C)(c1cc(-c2ccc(F)c(C=O)c2)c2ncccc2c1)S(C)(=O)=O -US08524751B2,1,C1COCCN1.Cc1ccc(S(=O)(=O)n2ncc3c(-c4nnc(CCl)o4)cc(Br)cc32)cc1>>Cc1ccc(S(=O)(=O)n2ncc3c(-c4nnc(CN5CCOCC5)o4)cc(Br)cc32)cc1 -US08618094B2,9,BrC(Br)(Br)Br.C[C@H](c1ccccc1)N1C[C@@](CCO)(C(=O)OC(C)(C)C)C(F)C1=O>>C[C@H](c1ccccc1)N1C[C@@](CCBr)(C(=O)OC(C)(C)C)C(F)C1=O -US06649643B1,8,C[SiH](C)Oc1c(C(O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)ccc2cc(C(C)(C)C)ccc12>>C[SiH](C)Oc1c(C(=O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)ccc2cc(C(C)(C)C)ccc12 -US20150005281A1,1,CN1C(=O)CCC1CN.Clc1ncc(Cl)c(Cl)n1>>CN1C(=O)CCC1CNc1nc(Cl)ncc1Cl -US20090105210A1,7,Cc1cc(C)c(-c2nc3c4c(nn3c(N)c2C#N)CSC4)c(C)c1>>Cc1cc(C)c(-c2nc3c4c(nn3c(N)c2CN)CSC4)c(C)c1 -US05162322,1,CC(C)N1CC(CCCCCl)OC1=O.Oc1ccccc1N1CCNCC1>>CC(C)N1CC(CCCCN2CCN(c3ccccc3O)CC2)OC1=O -US07354920B2,3,CC(C)Oc1ccccc1CCl.O=C(c1ccccc1)C1CN(Cc2ccccc2)CCO1>>CC(C)Oc1ccccc1CC(O)(c1ccccc1)C1CN(Cc2ccccc2)CCO1 -US20100035934A1,1,COc1ccc(N)cc1OC.Fc1cccc(-n2cccn2)n1>>COc1ccc(Nc2cccc(-n3cccn3)n2)cc1OC -US20130274469A1,2,COC(=O)c1ccc(OCc2c(-c3ccccc3F)noc2C)nc1.NCC(F)(F)C(F)(F)F>>Cc1onc(-c2ccccc2F)c1COc1ccc(C(=O)NCC(F)(F)C(F)(F)F)cn1 -US20100137445A1,2,CC(C)CN.COc1cc(C(=O)Cl)cc(OC)c1OC>>COc1cc(C(=O)NCC(C)C)cc(OC)c1OC -US20090054407A1,1,CC(C)(C)OC(=O)n1c(-c2cc(OCCCCl)c(Cl)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.OC1CCNCC1>>CC(C)(C)OC(=O)n1c(-c2cc(OCCCN3CCC(O)CC3)c(Cl)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21 -US20110028450A1,2,COc1cc2c(cc1N)-c1c(-c3cccs3)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCC3.O=C(Cl)CCl>>COc1cc2c(cc1NC(=O)CCl)-c1c(-c3cccs3)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCC3 -US08003662B2,3,COc1cc(F)c(B(O)O)cc1F.Cn1c(Nc2ccccc2)ncc(Br)c1=O>>COc1cc(F)c(-c2cnc(Nc3ccccc3)n(C)c2=O)cc1F -US20110312932A1,6,CCOC(=O)C(C)(C)S(=O)(=O)CCC(C)C>>CC(C)CCS(=O)(=O)C(C)(C)C(=O)O -US08946260B2,1,Brc1cccnc1.CC1Cc2ccc(C(F)(F)F)cc2C(=O)N1>>CC1Cc2ccc(C(F)(F)F)cc2C(=O)N1c1cccnc1 -US08987318B2,4,NN.O=C(CC(=O)C(F)(F)F)c1ccc(Br)cc1>>FC(F)(F)c1cc(-c2ccc(Br)cc2)[nH]n1 -US20070213321A1,1,O=C(CCl)N1CCCc2ccccc21.O=[N+]([O-])c1ccc2sc(S)nc2c1>>O=C(CSc1nc2cc([N+](=O)[O-])ccc2s1)N1CCCc2ccccc21 -US20060014965A1,9,CC(=O)N1CCc2c1cc(C)c(C(O)C(=O)O)c2C>>CC(=O)N1CCc2c1cc(C)c(CC(=O)O)c2C -US06479554B2,3,COc1ccccc1OC.O=C(Cl)c1ccc2c(c1)OCO2>>COc1ccc(C(=O)c2ccc3c(c2)OCO3)cc1OC -US20070213332A1,3,FC(F)(F)c1cccnc1Cl.O=c1cc(Cl)cn[nH]1>>O=c1cc(-c2ncccc2C(F)(F)F)cn[nH]1 -US20070293399A1,2,CC(=O)OC(C)=O.Nc1ncnc(N[C@@H]2CCCc3ccccc32)n1>>CC(=O)Nc1ncnc(N[C@@H]2CCCc3ccccc32)n1 -US20150284358A1,1,CCOC(=O)c1[nH]c(Br)nc1C.Clc1ccc(Cl)c(CBr)c1>>CCOC(=O)c1c(C)nc(Br)n1Cc1cc(Cl)ccc1Cl -US05591891,2,CC(=O)SCC(C(=O)O)C(C)c1ccccc1.C[C@H](N)C(=O)OCc1ccccc1>>CC(=O)SCC(C(=O)N[C@@H](C)C(=O)OCc1ccccc1)C(C)c1ccccc1 -US04296114,1,C[O-].O=c1c(Cl)nc2ccccc2n1-c1ccc(Cl)cc1>>COc1nc2ccccc2n(-c2ccc(Cl)cc2)c1=O -US06908930B2,3,Cc1[nH]c(C=O)c(C)c1C(=O)N1CCN(C)CC1.O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1>>Cc1[nH]c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)c(C)c1C(=O)N1CCN(C)CC1 -US08389513B2,2,C[C@]1(c2cc(N)ccc2F)N=C(N)OCC1(F)F.O=C(O)c1ncc(C(F)(F)F)cn1>>C[C@]1(c2cc(NC(=O)c3ncc(C(F)(F)F)cn3)ccc2F)N=C(N)OCC1(F)F -US20120270838A1,6,Cc1cc(C(=O)OC(C)(C)C)ccc1CCS(=O)(=O)N1CCC2(CC1)N=C(c1cc(OCc3ccccc3)cc(C(F)(F)F)c1)N(C(=O)OC(C)(C)C)C2=O>>Cc1cc(C(=O)OC(C)(C)C)ccc1CCS(=O)(=O)N1CCC2(CC1)N=C(c1cc(O)cc(C(F)(F)F)c1)N(C(=O)OC(C)(C)C)C2=O -US20100152442A1,2,CC(=O)OC(C)=O.COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OCC1CCNC1>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OCC1CCN(C(C)=O)C1 -US07741341B2,2,CC(C)N1CCC(NC(=O)c2nc3c(C(=O)O)cccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1.OCC1CC1>>CC(C)N1CCC(NC(=O)c2nc3c(C(=O)OCC4CC4)cccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1 -US07737166B2,1,C1COCCN1.Cc1c(-c2ccccc2)c(F)c2oc(Cl)nc2c1C#N>>Cc1c(-c2ccccc2)c(F)c2oc(N3CCOCC3)nc2c1C#N -US20090156642A1,6,CN(Cc1nc(-c2ccccc2F)c(S(=O)(=O)c2cccc(C(=O)N3CCCC3)c2)s1)C(=O)OC(C)(C)C>>CNCc1nc(-c2ccccc2F)c(S(=O)(=O)c2cccc(C(=O)N3CCCC3)c2)s1 -US20050239832A1,6,CCc1ccc2c(c1)C(NC[C@@H](O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)OC(C)(C)C)CCN2C>>CCc1ccc2c(c1)C(NC[C@@H](O)[C@@H](N)Cc1cc(F)cc(F)c1)CCN2C -US20050043315A1,2,CC(=O)Cl.CC(C)n1nc(-c2cnc(N)nc2-c2ccccc2)ccc1=O>>CC(=O)Nc1ncc(-c2ccc(=O)n(C(C)C)n2)c(-c2ccccc2)n1 -US06337305B1,1,COC(=O)CBr.Oc1ccc(Cc2ncc(C(F)(F)F)cc2Cl)c(Cl)c1Cl>>COC(=O)COc1ccc(Cc2ncc(C(F)(F)F)cc2Cl)c(Cl)c1Cl -US20140057953A1,3,COc1cccc(B(O)O)c1.COc1cccc(N(C)C(=O)c2ccc(Br)s2)c1>>COc1cccc(-c2ccc(C(=O)N(C)c3cccc(OC)c3)s2)c1 -US06573288B1,10,Cc1ccc(S(=O)(=O)c2ccccc2S(=O)(=O)N=CN(C)C)cc1.O=C1CCC(=O)N1Br>>CN(C)C=NS(=O)(=O)c1ccccc1S(=O)(=O)c1ccc(CBr)cc1 -US07452892B2,3,O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(Br)c(-c3ccc(Cl)cc3)ncn12.OCc1ccc(B(O)O)cc1>>O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(-c3ccc(CO)cc3)c(-c3ccc(Cl)cc3)ncn12 -US06018046,6,CC(C)(C)OC(=O)COc1cc2c(=O)c(Cc3cccnc3)cn3c4cc(Br)ccc4c(c1)c23>>O=C(O)COc1cc2c(=O)c(Cc3cccnc3)cn3c4cc(Br)ccc4c(c1)c23 -US06174503B1,1,CC(C)(C)c1cc(O)cc(C(C)(C)C)c1.OCCCCl>>CC(C)(C)c1cc(OCCCO)cc(C(C)(C)C)c1 -US20040192725A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc2cc[nH]c2c1>>COC(=O)c1ccc2ccn(C(=O)OC(C)(C)C)c2c1 -US04749702,1,CC(=O)N1CCC(CNc2nc3ccccc3s2)CC1.CI>>CC(=O)N1CCC(CN(C)c2nc3ccccc3s2)CC1 -US20100331328A1,1,N#Cc1cnc(N)cn1.O=S(=O)(Oc1cc2cccc(Br)c2cn1)C(F)(F)F>>N#Cc1cnc(Nc2cc3cccc(Br)c3cn2)cn1 -US20130303497A1,7,O=C1OC(=O)C2C3C=CC(C3)C12>>O=C1OC(=O)C2C3CCC(C3)C12 -US20100062970A1,1,C=CC#N.Cc1cccc(O)c1>>Cc1cccc(OCCC#N)c1 -US04018796,3,CCN(CC)c1ccc2ccc(=O)oc2c1.CN(C)C=O>>CCN(CC)c1ccc2cc(C=O)c(=O)oc2c1 -US20090018134A1,2,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3cccnc3C(=O)N(C)C)CC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3cccnc3C(=O)N(C)C)CC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US20080188528A1,2,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1ccn(Cc2ccccc2)c(=O)c1>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2ccn(Cc3ccccc3)c(=O)c2)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2 -US20090069384A1,1,CCOC(=O)c1cc2scc(Br)c2n1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C1CCCN1>>CCOC(=O)c1cc2scc(N3CCCC3=O)c2n1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20080318963A1,2,CCOC(=O)Nc1nc2cc(OC)c(OC)cc2nc1OC.Cc1cc(C)cc(N2CCNCC2)c1>>COc1cc2nc(NC(=O)N3CCN(c4cc(C)cc(C)c4)CC3)c(OC)nc2cc1OC -US20130131035A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.N#Cc1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CC=C(c2ccc(C#N)cc2)CC1 -US20120059002A1,1,COC(=O)c1cc(CBr)ccc1[N+](=O)[O-].O=C1NC(=O)c2ccccc21>>COC(=O)c1cc(CN2C(=O)c3ccccc3C2=O)ccc1[N+](=O)[O-] -US20050038112A1,3,C=CC[Mg+].COC(OC)[C@H]1[C@@H](CC=O)C(C)=CC[C@@H]1C(C)C>>C=CC[C@@H](O)C[C@H]1C(C)=CC[C@H](C(C)C)[C@H]1C(OC)OC -US20070293521A1,3,Brc1cnc(Nc2ccc3c(c2)OCCO3)nc1Nc1ccc2c(c1)OCCO2.OB(O)c1cccc(Cl)c1>>Clc1cccc(-c2cnc(Nc3ccc4c(c3)OCCO4)nc2Nc2ccc3c(c2)OCCO3)c1 -US20060257987A1,1,CCCC(CCOS(C)(=O)=O)Oc1ccc2c(-c3ccccc3)coc2c1.CCOC(=O)C(C)(C)Oc1ccc(O)cc1>>CCCC(CCOc1ccc(OC(C)(C)C(=O)OCC)cc1)Oc1ccc2c(-c3ccccc3)coc2c1 -US20100216813A1,1,BrCc1ccncc1.N#Cc1ccc(N(Cc2ccccc2C(F)(F)F)[C@H]2CCNC2)cc1>>N#Cc1ccc(N(Cc2ccccc2C(F)(F)F)[C@H]2CCN(Cc3ccncc3)C2)cc1 -US20040157894A1,1,O=C1C[C@@H](S)CN1Cc1ccc(Oc2ccccc2)cc1.OCCBr>>O=C1C[C@@H](SCCO)CN1Cc1ccc(Oc2ccccc2)cc1 -US20040067955A1,9,CC(C)n1nc(-c2cc(C#N)c(Cl)nc2-c2ccccc2)ccc1=O.N>>CC(C)n1nc(-c2cc(C#N)c(N)nc2-c2ccccc2)ccc1=O -US20110020460A1,1,CC(C)OC(=O)N1CCC(n2ncc(CO)c2C#N)CC1.Oc1ccc(Br)cc1F>>CC(C)OC(=O)N1CCC(n2ncc(COc3ccc(Br)cc3F)c2C#N)CC1 -US20100197692A1,9,NC(=O)c1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2s1>>N#Cc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2s1 -US06943174B2,7,COc1ccc(-c2nc3cccnc3[nH]2)cc1[N+](=O)[O-]>>COc1ccc(-c2nc3cccnc3[nH]2)cc1N -US20110224155A1,2,N#Cc1c(N)sc2c1CCOC2.O=C=NC(=O)c1ccccc1>>N#Cc1c(NC(=O)NC(=O)c2ccccc2)sc2c1CCOC2 -US20110269763A1,1,CCOC(=O)CBr.O=C(c1cnn(-c2ccccc2)c1)c1cc(F)ccc1O>>CCOC(=O)COc1ccc(F)cc1C(=O)c1cnn(-c2ccccc2)c1 -US08299085B2,1,C1CNC1.COC(=O)c1cc(F)c(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)c1cc(N2CCC2)c(C(F)(F)F)cc1[N+](=O)[O-] -US20150209257A1,7,CC(C)COc1nc(N)nc(N)c1N=O>>CC(C)COc1nc(N)nc(N)c1N -US20040229872A1,1,CN(C)C1(c2ccccc2)CCC(=O)CC1.NCCc1c[nH]c2ccc(OCc3ccccc3)cc12>>CN(C)C1(c2ccccc2)CCC(NCCc2c[nH]c3ccc(OCc4ccccc4)cc23)CC1 -US08088925B2,2,CC(C)(C)OC(=O)N1CC(N)C1.O=C1c2ccccc2C(=O)N1CCS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CC(NS(=O)(=O)CCN2C(=O)c3ccccc3C2=O)C1 -US06034067,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSC(=N)N>>CSC(=N)NC(=O)OC(C)(C)C -US04216160,1,CC(=O)NC(=O)CCl.SC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=O)NC(=O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1 -US07157487B2,1,BrCc1ccccc1.O=[N+]([O-])c1ccc(F)c(F)c1O>>O=[N+]([O-])c1ccc(F)c(F)c1OCc1ccccc1 -US09035059B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC[C@H]1CCOC[C@H]1F>>Cc1ccc(S(=O)(=O)OCC[C@H]2CCOC[C@H]2F)cc1 -US03957666,1,Clc1cccc(-c2cccc(Oc3cccc(Oc4ccccc4)c3)c2)c1.Oc1ccccc1Oc1ccccc1>>c1ccc(Oc2cccc(Oc3cccc(-c4cccc(Oc5ccccc5Oc5ccccc5)c4)c3)c2)cc1 -US20130267493A1,6,COC(=O)c1n[nH]c2cc(Cl)c(C#Cc3ccccc3)cc12>>O=C(O)c1n[nH]c2cc(Cl)c(C#Cc3ccccc3)cc12 -US20030144332A1,1,Fc1ccc(-c2nc(CI)co2)cc1.OCC1(CO)COCOC1>>OCC1(COCc2coc(-c3ccc(F)cc3)n2)COCOC1 -US07452905B2,2,CCOC(=O)[C@@H](N)Cc1ccc(N2C(=O)c3cccc(C)c3C2=O)cc1.Cc1cccc(Cl)c1C(=O)O>>CCOC(=O)[C@H](Cc1ccc(N2C(=O)c3cccc(C)c3C2=O)cc1)NC(=O)c1c(C)cccc1Cl -US20080045506A1,1,CC(C)N1CCN(C(=O)[C@H]2CCNC2)CC1.Cc1noc(-c2ccc(Br)c(F)c2)n1>>Cc1noc(-c2ccc(N3CC[C@H](C(=O)N4CCN(C(C)C)CC4)C3)c(F)c2)n1 -US20130253186A1,1,COC(=O)C1CCNCC1.Clc1nccnc1OC1CCN(c2ccc3ccccc3n2)CC1>>COC(=O)C1CCN(c2nccnc2OC2CCN(c3ccc4ccccc4n3)CC2)CC1 -US20110152254A1,6,COC(=O)c1cc(-c2ccccc2)cn1C>>Cn1cc(-c2ccccc2)cc1C(=O)O -US20110257137A1,1,CN1CCNCC1.Clc1ccc2cc(Br)c3nncn3c2c1>>CN1CCN(c2cc3ccc(Cl)cc3n3cnnc23)CC1 -US20110195956A1,3,COc1cccc2cnc(Cl)nc12.[Zn+]c1nccs1>>COc1cccc2cnc(-c3nccs3)nc12 -US04171356,1,BrCc1ccccc1.[N-]=[N+]=NC[C@@H]1C[C@H](O)C(O)=C(O)O1>>[N-]=[N+]=NC[C@@H]1C[C@H](OCc2ccccc2)C(O)=C(O)O1 -US08268822B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1cccc(Br)c1>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1 -US20110245303A1,1,CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CBr)c1.Cc1nnc(S)s1>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CSc2nnc(C)s2)c1 -US04371526,1,CCOC(=O)C(Cl)OC(=O)C(C)(C)C.CCOP(=O)(CCCCc1ccccc1)CC(=O)N1N=C(c2ccccc2)CC1C(=O)O>>CCOC(=O)C(OC(=O)C1CC(c2ccccc2)=NN1C(=O)CP(=O)(CCCCc1ccccc1)OCC)OC(=O)C(C)(C)C -US04139540,4,C=CCc1ccc(F)cc1.O=C(OO)c1cccc(Cl)c1>>Fc1ccc(CC2CO2)cc1 -US20060111440A1,3,C[Mg+].O=C(c1ccc(Br)cc1)C(F)(F)F>>CC(O)(c1ccc(Br)cc1)C(F)(F)F -US05891909,8,Cc1cc(OCCCO)cc(OS(=O)(=O)c2cccc3ccccc23)c1>>Cc1cc(OCCC=O)cc(OS(=O)(=O)c2cccc3ccccc23)c1 -US05192789,7,Cn1c2c(c3cc(OC(=O)CCl)ccc31)CCC2=O>>Cn1c2c(c3cc(O)ccc31)CCC2=O -US07960369B2,2,CCC(=O)Cl.Nc1nc2c(s1)CCc1ccccc1-2>>CCC(=O)Nc1nc2c(s1)CCc1ccccc1-2 -US20130004427A1,2,COC(=O)COc1ccc(N=Nc2ccc(CO)cc2)c(OC)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COC(=O)COc1ccc(N=Nc2ccc(COC(=O)Oc3ccc([N+](=O)[O-])cc3)cc2)c(OC)c1 -US20100009969A1,1,CC(=O)N1CCc2nc(-c3ccc(OCCCCl)cc3)sc2C1.CC1CCCN1>>CC(=O)N1CCc2nc(-c3ccc(OCCCN4CCCC4C)cc3)sc2C1 -US08372875B2,3,NC(=O)c1cc(Br)cc2c(C3CCS(=O)(=O)CC3)c[nH]c12.OB(O)c1ccccc1>>NC(=O)c1cc(-c2ccccc2)cc2c(C3CCS(=O)(=O)CC3)c[nH]c12 -US07999006B2,2,O=C(O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F.OCCC1(O)CNC1>>O=C(c1ccc(F)c(F)c1Nc1ccc(I)cc1F)N1CC(O)(CCO)C1 -US20100160379A1,7,O=[N+]([O-])/C=C/c1ccc(CCC2CCCO2)cc1>>O=[N+]([O-])CCc1ccc(CCC2CCCO2)cc1 -US04473709,1,CI.CN(C)Cc1ccccc1-c1ccccc1>>C[N+](C)(C)Cc1ccccc1-c1ccccc1 -US20090258854A1,1,Clc1nc2ncccc2s1.OCc1ccc(O)cc1>>OCc1ccc(Oc2nc3ncccc3s2)cc1 -US07304165B2,2,O=C(Cl)OCc1ccccc1.O=C(O)[C@@H]1C[C@@H](O)CN1>>O=C(O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1 -US20100279917A1,3,CC(=O)CC(C)CC(C)C.CCOC(=O)CC#N>>CCOC(=O)C(C#N)=C(C)CC(C)CC(C)C -US08658636B2,1,C1CC(N2CCOCC2)CCN1.CCOc1cc2nc(-c3cccc(C(F)(F)F)c3)c(CBr)c(C(=O)OC)c2cc1S(=O)(=O)CC>>CCOc1cc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(N4CCOCC4)CC3)c(C(=O)OC)c2cc1S(=O)(=O)CC -US03987042,7,CCOC(=O)CC1CC2CCN1CC2>>OCCC1CC2CCN1CC2 -US20130324557A1,2,CC(C)[C@@H](C)N.O=C(O)COc1cccc(Cl)c1>>CC(C)[C@@H](C)NC(=O)COc1cccc(Cl)c1 -US20150284358A1,6,CCOC(=O)c1c(C2CC2)nc(-c2cccnc2)n1Cc1cccc2ccccc12>>O=C(O)c1c(C2CC2)nc(-c2cccnc2)n1Cc1cccc2ccccc12 -US20150266881A1,2,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(C(=O)O)cc1.CNCc1ccccc1>>CN(Cc1ccccc1)C(=O)c1ccc([C@@H]2C[C@H]2NC(=O)OC(C)(C)C)cc1 -US20070032496A1,2,CC(=O)Cl.Nc1c(Cl)cn[nH]c1=O>>CC(=O)Nc1c(Cl)cn[nH]c1=O -US20150010541A1,2,C=C[C@H](CC(=O)OC(C)(C)C)OC(=O)[C@@H](N)C(C)C.CC(C)(C)OC(=O)NCc1nc(C(=O)NC(C)(C)C(=O)O)cs1>>C=C[C@H](CC(=O)OC(C)(C)C)OC(=O)[C@@H](NC(=O)C(C)(C)NC(=O)c1csc(CNC(=O)OC(C)(C)C)n1)C(C)C -US05387603,6,C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCCOCc1ccccc1)CC2)NCCOc1ccccc1OCC(F)(F)F>>C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCCO)CC2)NCCOc1ccccc1OCC(F)(F)F -US20110312974A1,1,CCN.CCOC(=O)Cn1nc(C)c(-c2ccc(C(F)(F)F)cc2C=O)c1C>>CCNCc1cc(C(F)(F)F)ccc1-c1c(C)nn(CC(=O)OCC)c1C -US20070213359A1,1,ClCCCI.O=C(NCc1cccc(Cl)c1)c1c[nH]c2ccccc12>>O=C(NCc1cccc(Cl)c1)c1cn(CCCCl)c2ccccc12 -US20070072792A1,1,C=CCBr.O=C(O)CCNC(=O)OCc1ccccc1>>C=CCN(CCC(=O)O)C(=O)OCc1ccccc1 -US20080287455A1,6,CC(C)(C)OC(=O)N1CCN(c2ncc(C(F)(F)F)cc2F)CC1>>Fc1cc(C(F)(F)F)cnc1N1CCNCC1 -US06005116,1,CC(C)(C)OC(=O)NCCO.Oc1noc(-c2cccnc2)c1Cl>>CC(C)(C)OC(=O)NCCOc1noc(-c2cccnc2)c1Cl -US05652233,7,C=CCOC(=O)c1cc([N+](=O)[O-])ccc1F>>C=CCOC(=O)c1cc(N)ccc1F -US20140364433A1,7,CC(C)(C)OC(=O)N1CC[C@H](O)[C@H]1C(=O)O>>CC(C)(C)OC(=O)N1CC[C@H](O)[C@H]1CO -US20100311966A1,6,COC(=O)c1cccc2[nH]c(N3CC[C@H](NC(=O)OCc4ccccc4)[C@H](OC)C3)nc12>>COC(=O)c1cccc2[nH]c(N3CC[C@H](N)[C@H](OC)C3)nc12 -US20100063077A1,5,Brc1cnc(Nc2cccc(OCc3ccccc3)c2)nc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(c1cccc(OCc2ccccc2)c1)c1ncc(Br)cn1 -US20090318470A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=S(=O)(c1cccc2ccccc12)c1n[nH]c2ccc(N3CCNCC3)cc12>>CC(C)(C)OC(=O)N1CCN(c2ccc3[nH]nc(S(=O)(=O)c4cccc5ccccc45)c3c2)CC1 -US06300344B1,6,CC(C)(C)c1cccc2c1CCC(NCc1ccccc1)C2O[SiH](c1ccccc1)c1ccccc1>>CC(C)(C)c1cccc2c1CCC(N)C2O[SiH](c1ccccc1)c1ccccc1 -US20070254931A1,8,CC(=O)Nc1nc(CCCc2ccc(CO)cc2)cs1>>CC(=O)Nc1nc(CCCc2ccc(C=O)cc2)cs1 -US07956216B2,2,CC(C)Cc1cccc(C(=O)O)c1.NCc1ccccc1>>CC(C)Cc1cccc(C(=O)NCc2ccccc2)c1 -US20140171430A1,2,Cc1nc(N2CC3CNCC3C2)nc(C)c1C.O=C(O)c1cccc(F)c1-n1nccn1>>Cc1nc(N2CC3CN(C(=O)c4cccc(F)c4-n4nccn4)CC3C2)nc(C)c1C -US07129243B2,1,CC(C)(C)OC(=O)N1CCC(Br)CC1.Sc1ccccn1>>CC(C)(C)OC(=O)N1CCC(Sc2ccccn2)CC1 -US08084611B2,1,CC[C@@H](N)CC(=O)O.FC(F)(F)c1ccc(Br)cc1>>CC[C@H](CC(=O)O)Nc1ccc(C(F)(F)F)cc1 -US20070155808A1,1,CCCN.Cc1oc(Cl)nc1-c1ccccc1>>CCCNc1nc(-c2ccccc2)c(C)o1 -US20040082611A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(CCO)C1.Oc1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(CCOc2ccccc2)C1 -US04031093,1,CCI.COC(=O)c1ccc(O)c(C(N)=O)c1>>CCOc1ccc(C(=O)OC)cc1C(N)=O -US20130012491A1,3,CC(C)Oc1ccc(B(O)O)cc1Cl.CCc1c(C=O)cccc1-c1cnc(Cl)nc1>>CCc1c(C=O)cccc1-c1cnc(-c2ccc(OC(C)C)c(Cl)c2)nc1 -US20110092547A1,1,CC(C)(C)OC(=O)C1CCC(O)CC1.O=[N+]([O-])c1ccc(F)nc1>>CC(C)(C)OC(=O)C1CCC(Oc2ccc([N+](=O)[O-])cn2)CC1 -US05354772,1,CC(C)Nc1ccccc1.O=C(CCl)c1ccc(F)cc1>>CC(C)N(CC(=O)c1ccc(F)cc1)c1ccccc1 -US20080090863A1,1,Cc1c[n+]([O-])c(Cl)cc1[N+](=O)[O-].N[C@@H]1CC[C@H](NC(=O)c2ccc(F)c(Cl)c2)CC1>>Cc1c[n+]([O-])c(N[C@@H]2CC[C@H](NC(=O)c3ccc(F)c(Cl)c3)CC2)cc1[N+](=O)[O-] -US20150284367A1,6,Cc1ccc(Nc2cc(OCCN3C(=O)c4ccccc4C3=O)nnc2C(N)=O)nc1C>>Cc1ccc(Nc2cc(OCCN)nnc2C(N)=O)nc1C -US20080306108A1,2,Cc1ncc(CN)c2c1OC(C)(C)OC2.N#Cc1ccc(C(=O)O)cc1>>Cc1ncc(CNC(=O)c2ccc(C#N)cc2)c2c1OC(C)(C)OC2 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C)nn1-c1cccc(C)c1>>Cc1cccc(-n2nc(C)cc2N2C[C@H](S(=O)(=O)c3ccccc3C(F)(F)F)C[C@H]2C(=O)O)c1 -US04372953,8,Cn1nnnc1SCCCS(=O)c1ccccn1.O=COO>>Cn1nnnc1S(=O)CCCS(=O)c1ccccn1 -US06432950B1,1,Cc1ncc[nH]1.FC(F)(F)c1cc2c(NCc3ccc4c(c3)OCO4)nc(Cl)nc2s1>>Cc1nccn1-c1nc(NCc2ccc3c(c2)OCO3)c2cc(C(F)(F)F)sc2n1 -US20150266895A1,7,O=Cc1nc(Cl)cc2c1c(N1CCOCC1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>OCc1nc(Cl)cc2c1c(N1CCOCC1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20140142083A1,2,CO.Cc1c(N)cncc1C(=O)O>>COC(=O)c1cncc(N)c1C -US07217723B2,5,CN(CC(O)c1ccc(F)cc1)S(=O)(=O)c1csc(Cl)c1.COCCl>>COCOC(CN(C)S(=O)(=O)c1csc(Cl)c1)c1ccc(F)cc1 -US20140228377A1,6,COC(=O)[C@@H]1CC[C@@H](C)N(C(=O)c2ccc(F)cc2-n2nccn2)C1>>C[C@@H]1CC[C@@H](C(=O)O)CN1C(=O)c1ccc(F)cc1-n1nccn1 -US20120122843A1,7,Cc1cnc(C(=O)CCl)s1>>Cc1cnc(C(O)CCl)s1 -US20150183801A1,1,CN(C(=O)OC(C)(C)C)[C@@H]1CCNC1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1>>CN(C(=O)OC(C)(C)C)[C@@H]1CCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2Br)C1 -US07514567B2,3,Brc1csc(Br)c1.CCCC[Sn](CCCC)(CCCC)c1ccccn1>>Brc1csc(-c2ccccn2)c1 -US20040072818A1,1,CC(C)(C)OC(=O)N1CCNCC1.COC(=O)c1cc(Cl)c2ccc(Cl)cc2n1>>COC(=O)c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)c2ccc(Cl)cc2n1 -US07618978B2,2,CCCNC.CCOC(=O)c1cc(CO)cc(C(=O)O)c1>>CCCN(C)C(=O)c1cc(CO)cc(C(=O)OCC)c1 -US06281363B1,6,CC(C)C[C@@H](C(=O)NN1C(=O)N[C@@H](C(C)C)C1=O)[C@H](CNC(=O)c1ccccc1)C(=O)NOC1CCCCO1>>CC(C)C[C@@H](C(=O)NN1C(=O)N[C@@H](C(C)C)C1=O)[C@H](CNC(=O)c1ccccc1)C(=O)NO -US20080227823A1,6,CC(C)(C)OC(=O)N1CCC(NC(=O)/C=C/c2ccc(F)c(Br)c2)(C(=O)NCCc2c[nH]c3ccc(F)cc23)CC1>>O=C(/C=C/c1ccc(F)c(Br)c1)NC1(C(=O)NCCc2c[nH]c3ccc(F)cc23)CCNCC1 -US04064340,6,COC(=O)[C@@H]1c2cc3c(c(O)c2[C@@H](O[C@@H]2O[C@@H](C)[C@H](OC)[C@@](C)(OC)[C@H]2OC)C[C@]1(C)O)C(=O)c1c(O)cc2c(c1C3=O)O[C@@H]1O[C@@]2(C)[C@H](O)[C@@H](N(C)C)[C@@H]1O>>CO[C@H]1[C@H](O[C@H]2C[C@](C)(O)[C@H](C(=O)O)c3cc4c(c(O)c32)C(=O)c2c(O)cc3c(c2C4=O)O[C@@H]2O[C@@]3(C)[C@H](O)[C@@H](N(C)C)[C@@H]2O)O[C@@H](C)[C@H](OC)[C@@]1(C)OC -US20070167427A1,9,COC(=O)c1cnc(Cl)c([N+](=O)[O-])c1.NN>>COC(=O)c1cnc(NN)c([N+](=O)[O-])c1 -US07220771B2,2,CC(C)(C)CN.COC(=O)c1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1>>CC(C)(C)CNC(=O)c1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1 -US04470972,6,COC(=O)[C@@H]1CC2(CN1C(=O)[C@H](C)NC(=O)OCc1ccccc1)SCCS2>>C[C@H](NC(=O)OCc1ccccc1)C(=O)N1CC2(C[C@H]1C(=O)O)SCCS2 -US20090227799A1,7,O=Cc1ccc(C=CC2CC2)s1>>OCc1ccc(C=CC2CC2)s1 -US07494992B2,6,Cc1cnc(C)c(N2CCN(Cc3ccccc3)CC2)n1>>Cc1cnc(C)c(N2CCNCC2)n1 -US04609650,1,CCC(C)C(=O)O.CC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]2(C)[C@H]1OC(=O)CBr>>CCC(C)C(=O)OCC(=O)O[C@H]1[C@@H](CC)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C -US20040167155A1,6,CCC1c2ccccc2-c2cc(Br)ccc2N1S(=O)(=O)c1ccc(OC)cc1>>CCC1c2ccccc2-c2cc(Br)ccc2N1S(=O)(=O)c1ccc(O)cc1 -US20130317065A1,2,COc1ccc2c(Cc3cccc(C(=O)O)n3)c(-c3ccccc3)n(S(=O)(=O)c3ccccc3)c2c1.CS(N)(=O)=O>>COc1ccc2c(Cc3cccc(C(=O)NS(C)(=O)=O)n3)c(-c3ccccc3)n(S(=O)(=O)c3ccccc3)c2c1 -US20110237573A1,2,Cc1cc(-c2ccc(CC(=O)O)cc2)ccn1.Nc1ccc(-c2ccccc2)cn1>>Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4ccccc4)cn3)cc2)ccn1 -US20090176847A1,9,COC1CC2CC(N=[N+]=[N-])CC2C1>>COC1CC2CC(N)CC2C1 -US20120142727A1,7,COC(=O)c1ccc2c(C=O)cnc(-c3c(F)cc(F)cc3F)c2c1>>COC(=O)c1ccc2c(CO)cnc(-c3c(F)cc(F)cc3F)c2c1 -US20110009399A1,7,COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)CC[C@@]34OCCc3cc(C(=O)O)ccc34)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)CC[C@@]34OCCc3cc(CO)ccc34)cc21 -US20090131459A1,1,CC(C)OCCO.NC(=O)c1[nH]cnc1N>>CC(C)OCCNc1nc[nH]c1C(N)=O -US20100113391A1,6,CC(C)(C)OC(=O)NCCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O>>NCCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O -US07868030B2,3,COc1ccc(B(O)O)cn1.Cc1ccsc1Br>>COc1ccc(-c2sccc2C)cn1 -US20130040930A1,6,COc1ccc(CN2CC(C)N(c3ccc(C(=O)N4CCN(c5ncc(C6CC6)cc5C)CC4)cn3)C2=O)cc1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3C(=O)NCC3C)nc2)CC1 -US20080269209A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=Cc1nn(-c2ccc(F)cc2)c2c1cc(-c1ccccc1)c1cnccc12>>CC(C)(C)OC(=O)N1CCC(NCc2nn(-c3ccc(F)cc3)c3c2cc(-c2ccccc2)c2cnccc23)CC1 -US20050176701A1,3,C#CCCC1(C2CCCC2)CC(=O)C(Cl)C(=O)O1.Oc1cccc(I)c1>>O=C1CC(CCC#Cc2cccc(O)c2)(C2CCCC2)OC(=O)C1Cl -US08569535B2,6,CCOC(=O)C1(NC(=O)c2cccc(C)c2C2=CCCC2)Cc2ccccc2C1>>Cc1cccc(C(=O)NC2(C(=O)O)Cc3ccccc3C2)c1C1=CCCC1 -US05968920,1,CC1(C)N[Se]c2ccccc21.CCBr>>CCN1[Se]c2ccccc2C1(C)C -US08828987B2,1,CC(C)(C)OC(=O)N1CCC(O)C1.Oc1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C(F)(F)F)cc2)C1 -US09079902B2,3,COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(-c4cc(Br)cc(C(F)(F)F)c4)cn(C)c3c2)c(OC)c1.OB(O)c1ccncc1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(-c4cc(-c5ccncc5)cc(C(F)(F)F)c4)cn(C)c3c2)c(OC)c1 -US20150158879A1,1,CS(=O)(=O)c1n[nH]c2cnccc12.Fc1cc(Cl)cc2nc(CCl)n(CCC(F)(F)F)c12>>CS(=O)(=O)c1nn(Cc2nc3cc(Cl)cc(F)c3n2CCC(F)(F)F)c2cnccc12 -US05208247,1,CCCCCCCCCCCCCCBr.COC(=O)Cc1ccc(O)c(Cl)c1>>CCCCCCCCCCCCCCOc1ccc(CC(=O)OC)cc1Cl -US20080269193A1,6,CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@H]4CCCC[C@@H]4OCc4ccccc4)c3)c2C1>>CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@H]4CCCC[C@@H]4O)c3)c2C1 -US20030114445A1,1,CCOC(=O)c1c[nH]c2cc(Cl)c(F)cc2c1=O.ICCCCI>>CCOC(=O)c1cn(CCCCI)c2cc(Cl)c(F)cc2c1=O -US20130245064A1,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1O.c1ccc(CC2CCNCC2)cc1>>O=C(c1ccc([N+](=O)[O-])cc1O)N1CCC(Cc2ccccc2)CC1 -US20080103123A1,6,CCCN(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CCCN(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCNCC1 -US20140363452A1,6,CC[C@H](C)[C@@H]([C@@H](CC(=O)OC(C)(C)C)OC)N(C)C(=O)[C@@H](NC(=O)[C@]1(C)CCCN1C)C(C)C>>CC[C@H](C)[C@@H]([C@@H](CC(=O)O)OC)N(C)C(=O)[C@@H](NC(=O)[C@]1(C)CCCN1C)C(C)C -US06207837B1,7,COc1cc(OC)cc(Sc2ccccc2C(=O)O)c1>>COc1cc(OC)cc(Sc2ccccc2CO)c1 -US06093732,2,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)cc(CCCO)cc2c1O>>CC(C)C(NC(=O)OC(C)(C)C)C(=O)OCCCc1cc(F)c2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2c1 -US07361670B2,6,COC(=O)c1cc2cc3[nH]c(=O)oc3cc2[nH]1>>O=C(O)c1cc2cc3[nH]c(=O)oc3cc2[nH]1 -US06114334,3,C=O.Cn1c(N)cc(=O)n1-c1ccccc1.c1cc2c(c(N3CCNCC3)c1)OCCO2>>Cn1c(N)c(CN2CCN(c3cccc4c3OCCO4)CC2)c(=O)n1-c1ccccc1 -US04608079,2,O=C(O)c1cc2ccoc2nc1C(=O)O>>O=C1OC(=O)c2nc3occc3cc21 -US06531599B2,1,Cc1cc(Br)ccc1CBr.c1c[nH]cn1>>Cc1cc(Br)ccc1Cn1ccnc1 -US05968930,7,O=C(c1ccc([N+](=O)[O-])cc1)N1Cc2cccn2Cc2sccc21>>Nc1ccc(C(=O)N2Cc3cccn3Cc3sccc32)cc1 -US06103736,1,Cc1ccc(C=O)cc1.Cc1ccccc1-c1nc2c3ccccc3ccn2c1N>>Cc1ccc(C=Nc2c(-c3ccccc3C)nc3c4ccccc4ccn23)cc1 -US06534496B1,2,CC(=O)OC(C)=O.O=C(CCC1CCNCC1)c1cc2c3c(c1)CCN3C(=O)CC2>>CC(=O)N1CCC(CCC(=O)c2cc3c4c(c2)CCN4C(=O)CC3)CC1 -US20130158075A1,2,Cc1nnc(CC2CCC(c3ncc(-c4ccc(N)cc4)s3)CC2)s1.O=C=Nc1cc(F)c(F)cc1F>>Cc1nnc(CC2CCC(c3ncc(-c4ccc(NC(=O)Nc5cc(F)c(F)cc5F)cc4)s3)CC2)s1 -US07605158B2,2,CNCCN(C)C.COC(=O)[C@@H]1CC[C@@H](C(=O)O)CC1>>COC(=O)[C@@H]1CC[C@@H](C(=O)N(C)CCN(C)C)CC1 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2ccccc2)cc1.O=C(O)c1c(F)c(F)cc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccccc2)C(=O)c2c(F)c(F)cc3cc[nH]c23)cc1 -US20110195932A1,1,CI.O=[N+]([O-])c1ccc2cc(-c3ccccc3)[nH]c2c1>>Cn1c(-c2ccccc2)cc2ccc([N+](=O)[O-])cc21 -US20120134934A1,1,O=C(CCl)c1ccccc1.O=C(NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1)c1ccccc1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(NC(=O)c1ccccc1)c1ccccc1)C2)c1ccccc1 -US20070149577A1,6,COc1ncc(F)cc1-c1ccc(C(C)N2C(=O)c3ccccc3C2=O)cc1>>COc1ncc(F)cc1-c1ccc(C(C)N)cc1 -US20090181950A1,2,CCCCc1cc(N2CCNCC2)c2nc(CCC(=O)OC)ccc2c1.O=C(O)Cc1ccc(OCCCN2CCCCCC2)cc1>>CCCCc1cc(N2CCN(C(=O)Cc3ccc(OCCCN4CCCCCC4)cc3)CC2)c2nc(CCC(=O)OC)ccc2c1 -US05541213,8,OCc1[nH]cnc1-c1ccccc1>>O=Cc1[nH]cnc1-c1ccccc1 -US20070043013A1,7,CC(C)(C)OC(=O)NC1(CC(=O)N2CC(Oc3ccc(Cl)cc3)C2)CCC1>>CC(C)(C)OC(=O)NC1(CCN2CC(Oc3ccc(Cl)cc3)C2)CCC1 -US20100324010A1,6,COC(=O)[C@@H]1C[C@H](N(CC(C)C)C(=O)c2cnc(C(C)(C)C)nc2NCc2ccco2)CN(C(=O)OC(C)(C)C)C1>>CC(C)CN(C(=O)c1cnc(C(C)(C)C)nc1NCc1ccco1)[C@H]1C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C1 -US08034812B2,2,CC(C)c1cc(C(=O)O)n(C)n1.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F>>CC(C)c1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2F)n(C)n1 -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCCNCC3)nn12.O=Cc1ccc(Cl)cc1>>FC(F)(F)c1nnc2ccc(N3CCCN(Cc4ccc(Cl)cc4)CC3)nn12 -US20040249150A1,6,Cc1cc(O[Si](C)(C)C(C)(C)C)ccc1NC(=S)Nc1nc(C(F)(F)F)cs1>>Cc1cc(O)ccc1NC(=S)Nc1nc(C(F)(F)F)cs1 -US20110306590A1,6,CC(C)(C)OC(=O)N1CC(c2nc3cc(Cl)ccc3[nH]2)C1>>Clc1ccc2[nH]c(C3CNC3)nc2c1 -US07964591B2,1,FC(F)(F)c1ccccc1CCl.O=C(NCCC1CC1)c1ccc(N2CCNCC2)nn1>>O=C(NCCC1CC1)c1ccc(N2CCN(Cc3ccccc3C(F)(F)F)CC2)nn1 -US07468391B2,6,CC(C)(C)c1cccc(C#C[Si](C)(C)C)c1>>C#Cc1cccc(C(C)(C)C)c1 -US04151302,9,CCOC(=O)CC(C)(O)c1ccc(-c2ccc(F)cc2F)cc1>>CCOC(=O)CC(C)c1ccc(-c2ccc(F)cc2F)cc1 -US05872115,2,CN(C)c1ccc(C(=O)O)c([N+](=O)[O-])c1.NC1CCN(C(c2ccccc2)c2ccccc2)CC1>>CN(C)c1ccc(C(=O)NC2CCN(C(c3ccccc3)c3ccccc3)CC2)c([N+](=O)[O-])c1 -US06017917,2,CN(C)CCN.COC(=O)c1cc(C(=O)O)cc(-c2cc(Cl)ccc2Cl)c1>>COC(=O)c1cc(C(=O)NCCN(C)C)cc(-c2cc(Cl)ccc2Cl)c1 -US20120316161A1,6,CCCC(C(=O)OC)c1c(C)nc2c(C)c(C(C)(C)C)nn2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2c(C)c(C(C)(C)C)nn2c1-c1ccc(C)cc1 -US07553969B1,6,CC(C)C(C(=O)NC(Cc1ccc(O)c(C(C)(C)C)c1)c1ncno1)N(C)C(=O)C(Cc1ccc(F)cc1)NC(=O)OC(C)(C)C>>CC(C)C(C(=O)NC(Cc1ccc(O)c(C(C)(C)C)c1)c1ncno1)N(C)C(=O)C(N)Cc1ccc(F)cc1 -US08436023B2,1,Nc1n[nH]c2ccc(C(F)(F)F)cc12.O=CC(=O)O>>O=C(O)CNc1n[nH]c2ccc(C(F)(F)F)cc12 -US05478845,2,COc1cc(N=C=O)cc(OC)c1OC.Cn1nc(C2CCN(CCCO)CC2)c2ccc(F)cc21>>COc1cc(NC(=O)OCCCN2CCC(c3nn(C)c4cc(F)ccc34)CC2)cc(OC)c1OC -US20150183801A1,1,C1CCNC1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCCC2)c(Br)c1 -US07732435B2,7,CC(C)C(=O)Oc1ccc2c(=O)c(-c3ccc(Cl)cc3)c(C(C)C)oc2c1>>CC(C)c1oc2cc(O)ccc2c(=O)c1-c1ccc(Cl)cc1 -US04443365,6,C=CCCCC(CCC)C(=O)OC>>C=CCCCC(CCC)C(=O)O -US07576098B2,6,CCOc1cc(O[Si](C)(C)C(C)(C)C)c(F)c(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)c2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1>>CCOc1cc(O)c(F)c(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)c2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1 -US20090192203A1,4,COC(=O)COc1ccc(OCCC(N)=S)cc1C.O=C(CBr)c1ccc(C(F)(F)F)cc1>>COC(=O)COc1ccc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)cs2)cc1C -US04144344,1,Brc1ccncc1.NCCN>>NCCNc1ccncc1 -US20100234356A1,1,O=C(c1ccc(Cl)cc1)N1CC(O)C(N2CCNCC2)C1.O=Cc1ccc(Cl)cc1>>O=C(c1ccc(Cl)cc1)N1CC(O)C(N2CCN(Cc3ccc(Cl)cc3)CC2)C1 -US20120114765A1,1,CC(=O)c1cc([N+](=O)[O-])c(Cl)s1.Cn1ccnc1S>>CC(=O)c1cc([N+](=O)[O-])c(Sc2nccn2C)s1 -US07625901B2,2,CC1(C)C(=O)N(CC(=O)O)[C@H](c2cc(F)cc(F)c2)C[C@@H]1O.Nc1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21>>CC1(C)C(=O)N(CC(=O)Nc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)[C@H](c2cc(F)cc(F)c2)C[C@@H]1O -US08765940B2,3,Cc1c(Cl)nc2cc(F)ccc2c1Cl.OB(O)c1cc(F)ccc1F>>Cc1c(-c2cc(F)ccc2F)nc2cc(F)ccc2c1Cl -US05545640,7,N#C[C@H](O)[C@H](Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1>>NC[C@@H](O)[C@H](Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1 -US20120010241A1,3,Cc1n[nH]c2cccc(OS(=O)(=O)C(F)(F)F)c12.OB(O)c1cnc2ccccc2c1>>Cc1n[nH]c2cccc(-c3cnc4ccccc4c3)c12 -US06815555B2,6,COC(=O)C=Cc1cc(C(C)C)c(OC)c(C(C)C)c1>>COC(=O)/C=C/c1cc(C(C)C)c(O)c(C(C)C)c1 -US20080269233A1,1,COC(=O)[C@@H]1CNC[C@H]1c1ccc(F)cc1F.N#Cc1ccc(Cl)nc1>>COC(=O)[C@@H]1CN(c2ccc(C#N)cn2)C[C@H]1c1ccc(F)cc1F -US04108890,2,Nc1cc(C(=O)Nc2cc(S(=O)(=O)O)cc3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)cc(C(=O)Nc2cc(S(=O)(=O)O)cc3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)c1.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(Nc1cc(C(=O)Nc2cc(S(=O)(=O)O)cc3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)cc(C(=O)Nc2cc(S(=O)(=O)O)cc3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c23)c1)Nc1cccc(C(F)(F)F)c1 -US05962682,2,C1COCCN1.COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(C(=O)O)cc2OCC(O)CO)c1>>COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(C(=O)N3CCOCC3)cc2OCC(O)CO)c1 -US06420410B1,7,O=[N+]([O-])c1ccccc1NCc1ccccc1>>Nc1ccccc1NCc1ccccc1 -US20060223829A1,6,CC(=O)N1CCc2cc(S(=O)(=O)N3CC[C@@H](N(C)C)C3)ccc21>>CN(C)[C@@H]1CCN(S(=O)(=O)c2ccc3c(c2)CCN3)C1 -US20080015202A1,9,CC(=O)Nc1nc(CCc2ccc(CC(=O)CN=[N+]=[N-])cc2)cs1>>CC(=O)Nc1nc(CCc2ccc(CC(=O)CN)cc2)cs1 -US04104273,2,CCOC(=O)CC#N.Cc1ccc(CN)cc1>>Cc1ccc(CNC(=O)CC#N)cc1 -US20080045504A1,1,CCNCC.N#Cc1ccc(F)cc1C(F)(F)F>>CCN(CC)c1ccc(C#N)c(C(F)(F)F)c1 -US07238714B2,2,COC(=O)c1ccc([C@H](C)N)cc1.Cc1cccc(Oc2ccc(Cl)cc2C(=O)O)c1>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2Oc2cccc(C)c2)cc1 -US20100249124A1,1,CC(c1ccc(O)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.CCOC(=O)c1cc(B(O)O)ccc1Cl>>CCOC(=O)c1cc(Oc2ccc(C(C)C(O)(c3ccc4c(c3)N(C)C(=O)CO4)C(F)(F)F)c(Cl)c2)ccc1Cl -US20150194612A1,3,CC(C)c1ccc(Cl)cn1.[Zn+]c1ccccn1>>CC(C)c1ccc(-c2ccccn2)cn1 -US20140323468A1,2,CC(=O)Cl.NCc1ccncc1Br>>CC(=O)NCc1ccncc1Br -US20050075394A1,6,CC1(C)OCc2cc([C@@H](O)CN(CCCCCCOCCOCc3cccc([N+](C)(C)C)c3)C(=O)OCc3ccccc3)ccc2O1>>CC1(C)OCc2cc([C@@H](O)CNCCCCCCOCCOCc3cccc([N+](C)(C)C)c3)ccc2O1 -US07317125B2,3,CC(C)N(NC(=O)c1ccccc1)C(=O)CSc1ccccc1Br.OB(O)c1ccccc1>>CC(C)N(NC(=O)c1ccccc1)C(=O)CSc1ccccc1-c1ccccc1 -US08389743B2,1,C1CCNC1.O=Cc1c(F)cc(Br)cc1F>>Fc1cc(Br)cc(F)c1CN1CCCC1 -US06313310B1,3,C#Cc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2.O=[N+]([O-])c1cccc(I)c1>>O=C1Nc2ccc(C#Cc3cccc([N+](=O)[O-])c3)cc2/C1=C/c1ccc[nH]1 -US08153658B2,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.OC[C@@H]1CCNC[C@H]1c1ccccc1>>O=C(N1CC[C@@H](CO)[C@H](c2ccccc2)C1)C(F)(F)F -US20080004321A1,6,CCCc1c(OCc2cccc(C(=O)OC)n2)ccc(C(C)=O)c1O>>CCCc1c(OCc2cccc(C(=O)O)n2)ccc(C(C)=O)c1O -US20140309219A1,1,O=C(N[C@H]1CCc2ccccc21)C1COCCN1c1nc(Cl)ncc1Br>>O=C1[C@@H]2COCCN2c2nc(Cl)ncc2N1C1CCc2ccccc21 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2ccc(Cl)cc2)cc1.O=C(O)c1ccc(Cl)c2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccc(Cl)cc2)C(=O)c2ccc(Cl)c3cc[nH]c23)cc1 -US20080153813A1,1,Clc1ccc2ncc(Cl)n2n1.NCc1ccccn1>>Clc1cnc2ccc(NCc3ccccn3)nn12 -US20110166116A1,7,CC(=O)c1cc(F)c(N2CCC(=NOC3CCN(C(=O)OC(C)C)CC3)CC2)cc1F>>CC(C)OC(=O)N1CCC(ON=C2CCN(c3cc(F)c(C(C)O)cc3F)CC2)CC1 -US20040102437A1,1,NCCF.O=C1CCC(Nc2ccc3[nH]ncc3c2)CC1>>FCCNC1CCC(Nc2ccc3[nH]ncc3c2)CC1 -US20080103173A1,2,N[C@H](c1cccc(F)c1)C1CC1.O=C(O)c1c(CN2CCCC2=O)c(-c2ccccc2)nc2ccccc12>>O=C(N[C@H](c1cccc(F)c1)C1CC1)c1c(CN2CCCC2=O)c(-c2ccccc2)nc2ccccc12 -US20140243302A1,9,Cc1c(C(N)=O)cnc2ccc(OCc3ccccc3)nc12>>Cc1c(C#N)cnc2ccc(OCc3ccccc3)nc12 -US04659503,1,CCCCCCI.Oc1ccc(-c2ccc(-c3cccs3)cn2)cc1>>CCCCCCOc1ccc(-c2ccc(-c3cccs3)cn2)cc1 -US20060287322A1,3,COC(=O)C(=O)Cl.[Mg+]C1CCCCC1>>COC(=O)C(=O)C1CCCCC1 -US04963561,2,CC(=O)OC(C)=O.Cc1nc2[nH]c(=O)[nH]c2cc1-c1ccc(N)cc1>>CC(=O)Nc1ccc(-c2cc3[nH]c(=O)[nH]c3nc2C)cc1 -US20090257979A1,7,CC(C)CC(=O)Nc1ncc[nH]1>>CC(C)CCNc1ncc[nH]1 -US20050043533A1,6,CC(C)(C)OC(=O)N1CCC(Oc2ccc(OC(F)(F)F)cc2)CC1>>FC(F)(F)Oc1ccc(OC2CCNCC2)cc1 -US20100234415A1,4,C#CCc1ccccc1.CCCOC(=O)Cc1c2n(c3ccccc13)CC(N=[N+]=[N-])CC2>>CCCOC(=O)Cc1c2n(c3ccccc13)CC(n1cc(Cc3ccccc3)nn1)CC2 -US08318757B2,3,C=C([Zn+])C(F)(F)F.FC(F)Oc1c(Cl)cc(Br)cc1Cl>>C=C(c1cc(Cl)c(OC(F)F)c(Cl)c1)C(F)(F)F -US08772048B2,9,CCCCCCCCBr.[N-]=[N+]=[N-]>>CCCCCCCCN=[N+]=[N-] -US20120022054A1,2,CNCc1ccccc1-c1ccccc1.O=C(O)CCCSc1ccc(O)cc1>>CN(Cc1ccccc1-c1ccccc1)C(=O)CCCSc1ccc(O)cc1 -US05470851,1,O=C1c2ccccc2C(=O)N1CCCCBr.c1ccc2c(c1)Cc1ccccc1N1CCNC[C@@H]21>>O=C1c2ccccc2C(=O)N1CCCCN1CCN2c3ccccc3Cc3ccccc3[C@@H]2C1 -US06472386B1,3,C#Cc1cc(OC)c(OC)c(OC)c1.CCOC(=O)c1csc(Br)n1>>CCOC(=O)c1csc(C#Cc2cc(OC)c(OC)c(OC)c2)n1 -US09108939B2,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1ccc([N+](=O)[O-])c(Cl)c1)OCC>>CC(C)(C)OC(=O)N1CCC(=Cc2ccc([N+](=O)[O-])c(Cl)c2)CC1 -US20090233956A1,1,C1COCCN1.COc1cc2c(-c3cc4cc(F)cnc4n3S(=O)(=O)c3ccc(C)cc3)cn(CCI)c2cc1OC>>COc1cc2c(-c3cc4cc(F)cnc4n3S(=O)(=O)c3ccc(C)cc3)cn(CCN3CCOCC3)c2cc1OC -US05616596,9,OC(c1cccnc1)c1cccs1>>c1cncc(Cc2cccs2)c1 -US20070155805A1,6,CCCCC(CC(=O)OCC)c1sc2cc(OC)ccc2c1C>>CCCCC(CC(=O)O)c1sc2cc(OC)ccc2c1C -US20150087585A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(N2CCC[C@@H](C(=O)N3CCCC3)C2)nc1N>>CC(C)(C)OC(=O)Nc1ccc(N2CCC[C@@H](C(=O)N3CCCC3)C2)nc1N -US20090156572A1,2,CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CNC[C@H]1c1ccc(Cl)c(Cl)c1.O=C(O)C1CCN(C(=O)CO)CC1>>CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CN(C(=O)C2CCN(C(=O)CO)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US06727264B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CCCCN)CC2)c1.O=C(Cl)c1cccc(Cl)c1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCNC(=O)c3cccc(Cl)c3)CC2)c1 -US20060264460A1,1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1cccc([N+](=O)[O-])c1>>N#Cc1cnc2ccc(NCc3cccc([N+](=O)[O-])c3)cc2c1Nc1ccc(F)c(Cl)c1 -US20150031689A1,1,CC(C)(C)OC(=O)N1CCC[C@H](N)C1.Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(Cl)ncnc32)cc1>>CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)C1 -US20060183736A1,6,COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(S(=O)(=O)CC(F)(F)F)cc3)ccc2c1>>O=S(=O)(CC(F)(F)F)c1ccc(-c2ccc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1 -US20060106075A1,7,CCCCOc1ccc(CC(=O)NCc2ccccc2)cc1>>CCCCOc1ccc(CCNCc2ccccc2)cc1 -US04224330,2,CC(C)C(C(=O)O)c1cc2cc(F)ccc2s1.OCc1[nH]ccc1Cc1ccccc1>>CC(C)C(C(=O)OCc1[nH]ccc1Cc1ccccc1)c1cc2cc(F)ccc2s1 -US20070010511A1,6,COC(=O)CCc1ccccc1OCCOC1CN(C(=O)OCc2ccccc2)CCC1c1ccc(OCCCOCc2ccccc2OC)cc1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OCc3ccccc3)CC2OCCOc2ccccc2CCC(=O)O)cc1 -US20120065196A1,6,CCOC(=O)C1(F)CCN(C(=O)NCCNC(=O)c2cn(-c3ccccc3)nc2C(F)(F)F)CC1>>O=C(NCCNC(=O)N1CCC(F)(C(=O)O)CC1)c1cn(-c2ccccc2)nc1C(F)(F)F -US05318966,7,COc1cccc2c1CC[C@H]1[C@@H]2CCN1C(=O)CC1CCCC1>>COc1cccc2c1CC[C@H]1[C@@H]2CCN1CCC1CCCC1 -US04021481,2,CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 -US20020013466A1,2,CCOC(=O)COc1ccccc1Oc1cc(N)c(F)cc1Cl.CCOC(=O)Cl>>CCOC(=O)COc1ccccc1Oc1cc(NC(=O)OCC)c(F)cc1Cl -US07560558B2,8,Cc1cccnc1C(O)c1cc(C)c(C)o1>>Cc1cccnc1C(=O)c1cc(C)c(C)o1 -US20140112945A1,2,COc1cc(OCC2CC2)c(-c2ncnc3c(C(=O)O)c(C)[nH]c23)cc1F.COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(C(C)(C)C)cc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1cc(OCC2CC2)c(-c2ncnc3c(C(=O)N[C@H](Cc4ccc(C(C)(C)C)cc4)C(=O)N4CCC(N5N=C(c6ccc(OC)c(OC)c6)[C@H]6CCCC[C@H]6C5=O)CC4)c(C)[nH]c23)cc1F -US05112998,2,CC(=O)O[C@@H]1CC2=C[C@@H](O)[C@H]3[C@@H]4CC[C@H](C(C)C5OCC(C)(C)CO5)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@H]2O[C@@H]12.CN(C)C(=O)Cl>>CC(=O)O[C@@H]1CC2=C[C@@H](OC(=O)N(C)C)[C@H]3[C@@H]4CC[C@H](C(C)C5OCC(C)(C)CO5)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@H]2O[C@@H]12 -US06281227B1,5,N[C@H]1CCN(CCc2ccc([N+](=O)[O-])cc2)C1=O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C1[C@@H](NC(=O)C(F)(F)F)CCN1CCc1ccc([N+](=O)[O-])cc1 -US05849911,2,CC(C)(C)OC(=O)NN(Cc1ccc(-c2cncs2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1.COC(=O)N[C@H](C(=O)O)C(C)(C)C>>COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(-c2cncs2)cc1)NC(=O)OC(C)(C)C)C(C)(C)C -US07425554B2,2,CC(C)(C)C1CCC(c2ccccc2N2CCNCC2)CC1.CCOC(=O)Cl>>CCOC(=O)N1CCN(c2ccccc2C2CCC(C(C)(C)C)CC2)CC1 -US04053472,1,CN(C)CCN.Cc1ccc(Cl)c([N+](=O)[O-])c1>>Cc1ccc(NCCN(C)C)c([N+](=O)[O-])c1 -US20150126490A1,7,CC(C)(C)[Si](C)(C)OC1C=C(c2cnc(N)cn2)CCC1>>CC(C)(C)[Si](C)(C)O[C@H]1CCC[C@@H](c2cnc(N)cn2)C1 -US07851473B2,2,N#Cc1cccc(N=C=O)c1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>N#Cc1cccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)c1 -US20140364412A1,7,O=[N+]([O-])c1cc(CO)ccc1F>>Nc1cc(CO)ccc1F -US20040254374A1,2,CC(C)(C)OC(=O)N[C@H](Cc1ccccn1)C(=O)O.CN1CCC(N2CCNCC2)CC1>>CN1CCC(N2CCN(C(=O)[C@@H](Cc3ccccn3)NC(=O)OC(C)(C)C)CC2)CC1 -US08354444B2,6,CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1>>CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1 -US05773512,7,O=C(c1ccccc1)c1ccccc1[N+](=O)[O-]>>Nc1ccccc1C(=O)c1ccccc1 -US20150038440A1,3,CC(=O)c1ccc(C2(F)CN(C(=O)OC(C)(C)C)C2)cc1.O=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F>>CC(C)(C)OC(=O)N1CC(F)(c2ccc(C(=O)CC(O)(c3cc(Cl)cc(Cl)c3)C(F)(F)F)cc2)C1 -US08344144B2,1,CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(N)s2)c(F)c1.O=C1c2ccc(Cl)nc2CN1C1COC1>>CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(Nc3ccc4c(n3)CN(C3COC3)C4=O)s2)c(F)c1 -US20030207868A1,7,N#Cc1ccc(NCCCCF)c([N+](=O)[O-])c1>>N#Cc1ccc(NCCCCF)c(N)c1 -US07582627B2,2,CC(O)C1(F)CCN(C(=O)OCc2ccccc2)C1.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)C1(F)CCN(C(=O)OCc2ccccc2)C1 -US05608056,6,C=CCOC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1CCN=[N+]=[N-]>>C=CCOC(=O)N1C[C@H](O)C[C@H]1CCN=[N+]=[N-] -US05646276,7,CC(=Cc1ccccc1)C(=O)O>>CC(Cc1ccccc1)C(=O)O -US06967196B1,9,BrC(Br)(Br)Br.CC(=O)OCc1ccc(Cl)cc1N([C@H](C)CCCO)S(=O)(=O)c1ccc(Cl)cc1>>CC(=O)OCc1ccc(Cl)cc1N([C@H](C)CCCBr)S(=O)(=O)c1ccc(Cl)cc1 -US20080056987A1,1,CCOC(=O)c1cnc2ccc3c(c2c1Cl)CCS3(=O)=O.CN(C)CCN>>CCOC(=O)c1cnc2ccc3c(c2c1NCCN(C)C)CCS3(=O)=O -US20100267666A1,9,COc1ccc(-c2cnc3c(n2)c(I)cn3S(=O)(=O)c2ccc(C)cc2)cc1OC.N#C[Cu]>>COc1ccc(-c2cnc3c(n2)c(C#N)cn3S(=O)(=O)c2ccc(C)cc2)cc1OC -US08071631B2,2,COc1ccc(S(=O)(=O)Cl)cc1OC.Nc1nc(-c2ccccc2)ns1>>COc1ccc(S(=O)(=O)Nc2nc(-c3ccccc3)ns2)cc1OC -US07572809B2,1,Clc1nc(Nc2cc[nH]n2)cc2ccccc12.Oc1ccc(F)cc1>>Fc1ccc(Oc2nc(Nc3cc[nH]n3)cc3ccccc23)cc1 -US07115635B2,6,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)Nc1cccc(-c2csc(SCC(=O)NC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)n2)c1>>O=C(CSc1nc(-c2cccc(NC(=O)[C@@H]3Cc4ccccc4CN3)c2)cs1)NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 -US20060264429A1,3,O=C(Cl)CCl.O=C1COc2c(F)cccc2N1>>O=C1COc2c(F)cc(C(=O)CCl)cc2N1 -US20090291950A1,7,COc1ccc2c(c1OC1CCCC1)OCC2=O>>COc1ccc2c(c1OC1CCCC1)OCC2O -US20090143354A1,1,C1CNCCN1.Cc1ccc2nc(Cl)ccc2c1NC(=O)CC1CCCCC1>>Cc1ccc2nc(N3CCNCC3)ccc2c1NC(=O)CC1CCCCC1 -US20100210619A1,2,Nc1ccc(O)cc1.O=C(O)c1cc(NC2CCCC2)ncn1>>O=C(Nc1ccc(O)cc1)c1cc(NC2CCCC2)ncn1 -US20080305169A1,1,O=C(Nc1ccccc1OCCCCl)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1>>O=C(c1cc(Cl)c(OCc2ccccc2)c(Cl)c1)N1CCCOc2ccccc21 -US08470816B2,2,CC(=O)O.CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1CCN(C(=O)CNC2CCNCC2)C[C@H]1c1ccc(Cl)c(Cl)c1>>CC(=O)N1CCC(NCC(=O)N2CC[C@@H](N(C)C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](c3ccc(Cl)c(Cl)c3)C2)CC1 -US20040044201A1,1,C=CCC(C)C=O.C=CCN>>C=CCNCC(C)CC=C -US08129376B2,6,CCOC(=O)CNC(=O)c1cc(-c2ccccc2OCc2ccccc2)on1>>O=C(O)CNC(=O)c1cc(-c2ccccc2OCc2ccccc2)on1 -US20100105655A1,1,CC(=O)N1CCNCC1.COc1cc(F)c(C#N)cc1[N+](=O)[O-]>>COc1cc(N2CCN(C(C)=O)CC2)c(C#N)cc1[N+](=O)[O-] -US20100152155A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])C1C2CNCC21>>CC(C)(C)OC(=O)N1CC2C(C1)C2[N+](=O)[O-] -US20140011881A1,6,CCOC(=O)c1ccc(C(F)(F)F)cc1OCC>>CCOc1cc(C(F)(F)F)ccc1C(=O)O -US05245046,1,Cc1cc2ccccc2[nH]1.ClCc1ccccc1>>Cc1cc2ccccc2n1Cc1ccccc1 -US20100063286A1,1,Cc1cccc(N2CCNCC2C)c1.O=CCCc1cc(-c2ccccc2)n(-c2ccccc2)n1>>Cc1cccc(N2CCN(CCCc3cc(-c4ccccc4)n(-c4ccccc4)n3)CC2C)c1 -US06469039B1,6,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2CC)c1ccccn1>>CCn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3ccccn3)ccc21 -US20060035956A1,1,CCOC(=O)Cn1ccc2ccc(O)cc21.OCCCC#Cc1ccc(C(F)(F)F)cc1>>CCOC(=O)Cn1ccc2ccc(OCCCC#Cc3ccc(C(F)(F)F)cc3)cc21 -US07452993B2,2,C1CCNC1.COc1ccccc1-c1n[nH]c2ncc(-c3cncc(C(=O)O)c3)cc12>>COc1ccccc1-c1n[nH]c2ncc(-c3cncc(C(=O)N4CCCC4)c3)cc12 -US20090286792A1,1,N[C@H]1CCN(C(=O)C2CCN(c3cccc(C(F)(F)F)c3)CC2)C1.O=C1CCC(O)(c2ccccn2)CC1>>O=C(C1CCN(c2cccc(C(F)(F)F)c2)CC1)N1CC[C@H](NC2CCC(O)(c3ccccn3)CC2)C1 -US05736539,4,ClCCNCCCl.Nc1cccc2c1CCCC2>>c1cc2c(c(N3CCNCC3)c1)CCCC2 -US20150152108A1,6,Cc1nc(NC(=O)N2c3nc(-c4cccc(C(F)(F)F)c4)ccc3N3C[C@@H]2[C@H](O[Si](C)(C)C(C)(C)C)C3)sc1C>>Cc1nc(NC(=O)N2c3nc(-c4cccc(C(F)(F)F)c4)ccc3N3C[C@@H]2[C@H](O)C3)sc1C -US20090186886A1,7,N#CCN1CCCOCC1>>NCCN1CCCOCC1 -US08809336B2,6,CC(C)(C)OC(=O)NC1CCN(c2ccnc3[nH]ccc23)CC1>>NC1CCN(c2ccnc3[nH]ccc23)CC1 -US05739129,2,COc1ccc(N(C(=O)CN2C(=O)C(N)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1.O=C=Nc1ccccc1>>COc1ccc(N(C(=O)CN2C(=O)C(NC(=O)Nc3ccccc3)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1 -US20060084690A1,2,CCN1NN=CC1CCOc1ccc(N)cc1.O=C(O)CCCc1cnoc1-c1ccccc1>>CCN1NN=CC1CCOc1ccc(NC(=O)CCCc2cnoc2-c2ccccc2)cc1 -US08476297B2,2,FC(F)(F)c1ccc(C2NCCc3ccccc32)cc1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)N1CCc2ccccc2C1c1ccc(C(F)(F)F)cc1 -US09035059B2,2,Nc1cccc([N+](=O)[O-])c1O.O=C(O)CCl>>O=C(CCl)Nc1cccc([N+](=O)[O-])c1O -US20100331306A1,4,CCC(=O)CC(=O)OC.Nc1ccc(F)cc1>>CCc1cc(=O)c2cc(F)ccc2[nH]1 -US05670675,2,CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)C(N)Cc1ccccc1.Cc1ccc(S(=O)(=O)N[C@H](C(=O)O)C(C)C)cc1>>Cc1ccc(S(=O)(=O)N[C@H](C(=O)NC(Cc2ccccc2)C(O)C(Cc2ccccc2)NC(=O)OC(C)(C)C)C(C)C)cc1 -US05466861,6,C=C(c1ccc(C(=O)OC)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C>>C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C -US05223518,3,Brc1cccnc1.C#CC(O)c1ccccc1>>OC(C#Cc1cccnc1)c1ccccc1 -US20130296569A1,4,C[S+](C)(C)=O.O=C1CCN(c2c(F)cc([N+](=O)[O-])cc2F)CC1>>O=[N+]([O-])c1cc(F)c(N2CCC3(CC2)CO3)c(F)c1 -US07989461B2,7,Cc1ccc2c(Nc3cccc(C(F)(F)F)c3)nccc2c1[N+](=O)[O-]>>Cc1ccc2c(Nc3cccc(C(F)(F)F)c3)nccc2c1N -US20090069340A1,1,Cn1c(CBr)c(Br)c(=O)n1C1CCCCC1.c1ccc(CCCC2CCNCC2)cc1>>Cn1c(CN2CCC(CCCc3ccccc3)CC2)c(Br)c(=O)n1C1CCCCC1 -US20090023753A1,2,CC(=O)OCC(=O)Cl.Nc1cc(CCl)ccn1>>CC(=O)OCC(=O)Nc1cc(CCl)ccn1 -US20060142211A1,1,CCOC(=O)CBr.COc1cc2oc(-c3ccc(N)cc3)cc(=O)c2c(OC)c1OC>>CCOC(=O)CNc1ccc(-c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2)cc1 -US20120207763A1,4,CC#CC(=O)OC.Clc1ncc(Br)c(NC2CCCC2)n1>>COC(=O)c1c(C)c2cnc(Cl)nc2n1C1CCCC1 -US20100130474A1,2,COc1ccc(-c2cc(N)[nH]n2)cn1.O=C(O)CCCN1CCCC1>>COc1ccc(-c2cc(NC(=O)CCCN3CCCC3)[nH]n2)cn1 -US20120184542A1,7,Cc1ccc(C(=O)OCc2ccccc2)cc1[N+](=O)[O-]>>Cc1ccc(C(=O)OCc2ccccc2)cc1N -US20120142647A1,1,CNOC.Clc1nc(Cl)nc(Cl)n1>>CON(C)c1nc(Cl)nc(Cl)n1 -US20100041654A1,1,Nc1cc(F)ccc1Cl.O=C(NCC1CCCC1)c1cnc(Cl)nc1C(F)(F)F>>O=C(NCC1CCCC1)c1cnc(Nc2cc(F)ccc2Cl)nc1C(F)(F)F -US07759399B2,7,CC1(C)C(=O)C=CC1=O>>CC1(C)C(=O)C=CC1O -US08519135B2,1,COCCl.CON(C)C(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>COCN(c1cc(Cl)cnc1C(=O)N(C)OC)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US06995263B2,7,COCCc1nc(-c2ccc(C(F)(F)F)cc2)nc(C)c1C(=O)OC>>COCCc1nc(-c2ccc(C(F)(F)F)cc2)nc(C)c1CO -US09139580B2,2,C=C(C)c1cccc(C(C)(C)N=C=O)c1.N#CC1(O)CN2CCC1CC2>>C=C(C)c1cccc(C(C)(C)NC(=O)OC2(C#N)CN3CCC2CC3)c1 -US04560697,3,FC(F)(F)I.O=C(CCl)CCl>>OC(CCl)(CCl)C(F)(F)F -US20100063286A1,1,CC(C)(C)n1nc(CCC=O)cc1-c1ccccc1.Cc1cccc(N2CCNCC2)c1C>>Cc1cccc(N2CCN(CCCc3cc(-c4ccccc4)n(C(C)(C)C)n3)CC2)c1C -US06521643B1,7,C[SiH](C)Oc1ccnc(-c2cccc([N+](=O)[O-])c2)c1C(C)(C)C>>C[SiH](C)Oc1ccnc(-c2cccc(N)c2)c1C(C)(C)C -US08828996B2,6,CC(C)(C)OC(=O)N1CCC2(CC1)CN(Cc1ccccc1)CC(C)(C)O2>>CC1(C)CN(Cc2ccccc2)CC2(CCNCC2)O1 -US08288403B2,1,Cc1cn(-c2ccc(Br)cc2C#N)cn1.Nc1ncn(-c2ccccc2Cl)n1>>Cc1cn(-c2ccc(Nc3ncn(-c4ccccc4Cl)n3)cc2C#N)cn1 -US08063046B2,2,CCN.COc1ccc(C(=O)O)cc1/C=C/c1ccc(OC(F)(F)F)cc1>>CCNC(=O)c1ccc(OC)c(/C=C/c2ccc(OC(F)(F)F)cc2)c1 -US20150038528A1,2,CCOC(=O)c1ncc2cc(NC(=O)NC3CCCCC3)ccc2c1O.NCCC(=O)O>>O=C(O)CCNC(=O)c1ncc2cc(NC(=O)NC3CCCCC3)ccc2c1O -US04046900,7,COc1ccc2c(CCCN3CCC(C(=O)c4ccc(F)cc4)CC3)c(C)[nH]c2c1>>COc1ccc2c(CCCN3CCC(C(O)c4ccc(F)cc4)CC3)c(C)[nH]c2c1 -US20110224204A1,1,ClCc1ccc2ccccc2n1.O=[N+]([O-])c1cccc(-c2ccncc2)c1-c1ccc(O)cc1>>O=[N+]([O-])c1cccc(-c2ccncc2)c1-c1ccc(OCc2ccc3ccccc3n2)cc1 -US09120749B2,3,CN(C)[C@@H]1CC[C@@H](Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)CC1.COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O>>COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(N[C@@H]4CC[C@@H](N(C)C)CC4)c3c2)ccc1O -US20110105544A1,2,CO.O=C(O)CCCCc1ccccc1>>COC(=O)CCCCc1ccccc1 -US04294843,2,CCOC(=O)Cl.Nc1ccccc1SCc1ncon1>>CCOC(=O)Nc1ccccc1SCc1ncon1 -US05264415,1,C=CCI.O=C(O)C(CCc1ccc(Cl)cc1)(Cn1cncn1)c1ccccc1>>C=CCOC(=O)C(CCc1ccc(Cl)cc1)(Cn1cncn1)c1ccccc1 -US07169808B2,1,BrC1CCCC1.COc1ccc(C(=O)CCC(=O)O)cc1O>>COc1ccc(C(=O)CCC(=O)O)cc1OC1CCCC1 -US20100093731A1,1,C1CCNCC1.COc1nc(Cl)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1>>COc1nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)nc(N2CCCCC2)n1 -US07834051B2,1,CC1NC(=O)C(C)(C)C1=O.COc1cc(I)ccc1C#N>>COc1cc(N2C(=O)C(C)(C)C(=O)C2C)ccc1C#N -US08592460B2,1,CC1(C)OCC(O)CO1.CCc1cc(-c2noc(-c3cc(C)nc(N(CC)CC)c3)n2)cc(C)c1O>>CCc1cc(-c2noc(-c3cc(C)nc(N(CC)CC)c3)n2)cc(C)c1OC1COC(C)(C)OC1 -US20040077853A1,1,CCc1cc(-c2cccc(NC(=O)C(C)(C)C)n2)c(OC)cc1CC=O.CNC>>CCc1cc(-c2cccc(NC(=O)C(C)(C)C)n2)c(OC)cc1CCN(C)C -US20130245000A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Cl)nc2)CC1.O=C(NCCO)c1ccc2[nH]ccc2c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(-n3ccc4cc(C(=O)NCCO)ccc43)nc2)CC1 -US20110015408A1,2,COC(=O)[C@H]1NCC[C@H]1O.Cc1c(S(=O)(=O)O)ccc(C#N)c1Cl>>COC(=O)[C@@H]1[C@H](O)CCN1S(=O)(=O)c1ccc(C#N)c(Cl)c1C -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)Cc4cscn4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](Cc4cscn4)NC(=O)c4c[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US20120122848A1,2,O=C(Cl)OCc1ccccc1.Oc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)NCC3>>O=C(OCc1ccccc1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc13 -US07368578B2,8,COc1cc(COc2nn(-c3ccccc3)cc2/C=C/CO)ccc1OCc1nc(-c2ccco2)oc1C>>COc1cc(COc2nn(-c3ccccc3)cc2/C=C/C=O)ccc1OCc1nc(-c2ccco2)oc1C -US20140213571A1,6,CCOC(=O)C(O)c1c2n(c3cccc(F)c13)COc1ccc(-c3cc4c(C(=O)NC)c(-c5ccc(F)cc5)oc4cc3N(C)S(C)(=O)=O)nc1-2>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3c(C(O)C(=O)O)c5c(F)cccc5n3CO4)cc12 -US20090156610A1,1,CS(=O)(=O)OC1CCSCC1.O=Cc1cc(F)ccc1O>>O=Cc1cc(F)ccc1OC1CCSCC1 -US08975254B2,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1c[nH]cn1>>N#Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US05677316,2,CCOC(=O)C1(C(=O)[O-])CC(=O)N(Cc2ccccc2)C1.NCc1ccccc1>>CCOC(=O)C1(C(=O)NCc2ccccc2)CC(=O)N(Cc2ccccc2)C1 -US20090181942A1,6,CCOC(=O)CC1CCN(C(=O)CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c(C#N)ccc32)CC1>>COc1cccc([C@H]2O[C@H](CCC(=O)N3CCC(CC(=O)O)CC3)c3ccc(C#N)n3-c3ccc(Cl)cc32)c1OC -US07696223B2,4,CCOC(=O)C(CC(=O)C(C)(C)C)C(C)=O.Nc1ccc(F)cc1>>CCOC(=O)c1cc(C(C)(C)C)n(-c2ccc(F)cc2)c1C -US05663366,1,NCc1ccccc1.O=[N+]([O-])c1c(Br)nn(CCO)c1Br>>O=[N+]([O-])c1c(Br)nn(CCO)c1NCc1ccccc1 -US20130267494A1,2,CC(C)(C)OC(=O)N1CCOC(CN)C(c2ccc(Cl)c(Cl)c2)C1.O=C(O)Cn1cncn1>>CC(C)(C)OC(=O)N1CCOC(CNC(=O)Cn2cncn2)C(c2ccc(Cl)c(Cl)c2)C1 -US20120157479A1,3,C=CCN(CC=C)C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CC=CC1 -US20100120859A1,1,COC(=O)CC1(COS(C)(=O)=O)CC1.COCCCc1cc(O)cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1>>COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)cc(OCC2(CC(=O)OC)CC2)c1 -US04024273,1,O=C(CBr)c1ccc(Cl)cc1.Oc1ccccc1>>O=C(COc1ccccc1)c1ccc(Cl)cc1 -US05169853,6,CCOC(=O)c1cn(C2CC2)c2cc(-c3cc(C)nc(COC(C)=O)c3)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2cc(-c3cc(C)nc(CO)c3)c(F)cc2c1=O -US20100279995A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCCNC>>CNCCN(C)C(=O)OC(C)(C)C -US06124313,2,Cc1cccc(N)c1CNc1cccn2c(C=O)c(C)nc12.O=C(Cl)OCCCl>>Cc1cccc(NC(=O)OCCCl)c1CNc1cccn2c(C=O)c(C)nc12 -US20040077646A1,6,Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)NC(C#N)CC2CCN(C(=O)OC(C)(C)C)CC2)cc2ccccc21>>Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)NC(C#N)CC2CCNCC2)cc2ccccc21 -US05798316,7,COC(=O)C(C)Oc1cccc(C=O)c1>>COC(=O)C(C)Oc1cccc(CO)c1 -US07663301B2,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Cc1c(C2CCCCC2)csc1C=O>>C=Cc1scc(C2CCCCC2)c1C -US08697725B2,6,COC(=O)c1ccc(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)c(C)c1>>CC(=O)N1c2ccc(-c3ccc(C(=O)O)cc3C)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C -US07279580B2,3,CC1(C)COB(c2ccc(F)c(-c3ccc(F)cc3C#N)c2)OC1.Fc1cccn2c(Br)cnc12>>N#Cc1cc(F)ccc1-c1cc(-c2cnc3c(F)cccn23)ccc1F -US04157257,2,CC(C)(N)c1ccccc1.O=S(=O)(Cl)c1ccccc1>>CC(C)(NS(=O)(=O)c1ccccc1)c1ccccc1 -US08293757B2,1,CCN(CC)CCCl.O=[N+]([O-])c1ccc(O)cc1>>CCN(CC)CCOc1ccc([N+](=O)[O-])cc1 -US07576215B2,1,COc1ccc(F)cc1C=O.Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>COc1ccc(F)cc1CNc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 -US20140296226A1,9,NC1=N[C@@]2(CCO1)c1cc(Br)ccc1Oc1c2cc(Cl)nc1F.[N-]=[N+]=[N-]>>[N-]=[N+]=Nc1ccc2c(c1)[C@@]1(CCOC(N)=N1)c1cc(Cl)nc(F)c1O2 -US05641788,1,CCCCCC(=O)c1c(CBr)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1.Cn1ccnc1S>>CCCCCC(=O)c1c(CSc2nccn2C)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1 -US20100226994A1,7,CCCCCCCCCCCCCCCC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C>>CC1=C(/C=C/C(C)=C/C=C/C(C)=C/CO)C(C)(C)CCC1 -US20120165329A1,2,Ic1c[nH]c2ncnc(C3CCCC3)c12.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)n1cc(I)c2c(C3CCCC3)ncnc21 -US07872028B2,1,CCc1ccccc1B(O)O.Oc1ccccc1Br>>CCc1ccccc1Oc1ccccc1Br -US06506782B1,2,CCC(N)C(=O)OCC(C)C.O=C(O)Cc1cccc(F)c1>>CCC(NC(=O)Cc1cccc(F)c1)C(=O)OCC(C)C -US20060148838A1,7,CCOC(=O)c1c(-c2cc(C)c(O)c(C)c2)c(C)n2c1-c1cc([N+](=O)[O-])c(OC)cc1CC2>>CCOC(=O)c1c(-c2cc(C)c(O)c(C)c2)c(C)n2c1-c1cc(N)c(OC)cc1CC2 -USRE030293,1,CI.O=C1CCNc2ccc(Cl)cc2N1c1ccccc1>>CN1CCC(=O)N(c2ccccc2)c2cc(Cl)ccc21 -US20070232627A1,7,O=C(Nc1ccc(Sc2ccc(O)cc2)c([N+](=O)[O-])c1)c1cccs1>>Nc1cc(NC(=O)c2cccs2)ccc1Sc1ccc(O)cc1 -US08741892B2,8,CC(=O)NC1CCN(C(=O)OCc2ccccc2)CCC1O>>CC(=O)NC1CCN(C(=O)OCc2ccccc2)CCC1=O -US20140038975A1,6,C[C@@](CCn1cc(-c2nc3ccccc3o2)cn1)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>C[C@@](CCn1cc(-c2nc3ccccc3o2)cn1)(C(=O)NO)S(C)(=O)=O -US20140058098A1,1,Brc1ccc2c(c1)OCCn1cc(-c3ncc[nH]3)nc1-2.CC(C)I>>CC(C)n1ccnc1-c1cn2c(n1)-c1ccc(Br)cc1OCC2 -US07326699B2,2,CC(C)(C)N=C=O.NC[C@@H]1C[C@H](n2cc(-c3cccc(OCc4ccccc4)c3)c3c(N)ncnc32)C1>>CC(C)(C)NC(=O)NC[C@@H]1C[C@H](n2cc(-c3cccc(OCc4ccccc4)c3)c3c(N)ncnc32)C1 -US06617325B1,1,COC(=O)CC(C)(CCCBr)c1ccccc1.O=C(NC1CCNCC1)c1ccccc1-c1ccccc1>>COC(=O)CC(C)(CCCN1CCC(NC(=O)c2ccccc2-c2ccccc2)CC1)c1ccccc1 -US20120157432A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.NC1CC1>>CC(C)(C)OC(=O)N1CCC(C(=O)NC2CC2)CC1 -US20130012496A1,3,CCOC(=O)N1CCc2ccc(NC(=O)C=C(C)C)cc2CC1>>CCOC(=O)N1CCc2cc3c(cc2CC1)C(C)(C)CC(=O)N3 -US20100204228A1,3,Cn1c(C#N)ccc1B(O)O.NS(=O)(=O)c1ccc(Br)c(F)c1>>Cn1c(C#N)ccc1-c1ccc(S(N)(=O)=O)cc1F -US08415345B2,1,CC(C)CN.O=S(=O)(Nc1cccc(-c2nc(C3CCOCC3)sc2-c2ccnc(Cl)n2)c1F)c1ccoc1>>CC(C)CNc1nccc(-c2sc(C3CCOCC3)nc2-c2cccc(NS(=O)(=O)c3ccoc3)c2F)n1 -US07566736B2,2,NC(=O)c1[nH]c2ccccc2c1-c1ccc(N)cc1.O=S(=O)(Cl)c1cc(C(F)(F)F)ccc1F>>NC(=O)c1[nH]c2ccccc2c1-c1ccc(NS(=O)(=O)c2cc(C(F)(F)F)ccc2F)cc1 -US20090176850A1,3,CON(C)C(=O)c1cccc(Br)c1.Cc1cccc([Mg+])c1>>Cc1cccc(C(=O)c2cccc(Br)c2)c1 -US20140057920A1,2,Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)O)cn1C1CCCC1.Cc1nnc(CN)o1>>Cc1nnc(CNC(=O)c2cn(C3CCCC3)c(C)c(-c3cccc(C(F)F)c3)c2=O)o1 -US20090105305A1,2,COCC(=O)Cl.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)CCN>>COCC(=O)NCCS(=O)(=O)Nc1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)ccc1C -US05527805,8,COc1ccc2ncc3c(c2c1)CCCC3.O=C(OO)c1cccc(Cl)c1>>COc1ccc2c(c1)c1c(c[n+]2[O-])CCCC1 -US20120196848A1,7,C=C(c1csc2c1OCCN(C(=O)OC(C)(C)C)C2)C(F)(F)F>>CC(c1csc2c1OCCN(C(=O)OC(C)(C)C)C2)C(F)(F)F -US04331683,1,C=[N+]=[N-].CCCCCCCCCCNC(=O)C=Cc1cccc(NC(=O)/C=C\C(=O)O)c1>>CCCCCCCCCCNC(=O)C=Cc1cccc(NC(=O)/C=C\C(=O)OC)c1 -US03988143,1,C#CC(C)(C)N.O=CCCBr>>C#CC(C)(C)NCCC=O -US08815869B2,2,CC(C)(C)OC(=O)N1CCC(N)CC1.O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O>>CC(C)(C)OC(=O)N1CCC(NC(=O)CN2CCCC(c3ccccc3)(c3ccccc3)C2=O)CC1 -US20040186101A1,3,CC1(C)OC(=O)Nc2ccc(B(O)O)cc21.N#Cc1cc(Br)co1>>CC1(C)OC(=O)Nc2ccc(-c3coc(C#N)c3)cc21 -US20140378487A1,1,O=Cc1ccc(F)cn1.Oc1ccc(F)c(C(F)(F)F)c1>>O=Cc1ccc(Oc2ccc(F)c(C(F)(F)F)c2)cn1 -US07157487B2,2,CCOC(=O)Cc1ccc(N)c(Cl)c1.O=C(O)c1c[nH]c2ccccc12>>CCOC(=O)Cc1ccc(NC(=O)c2c[nH]c3ccccc23)c(Cl)c1 -US08178522B2,2,Cc1onc(-c2ccc(F)cn2)c1CCc1ncc(C(=O)O)s1.NCC(F)(F)F>>Cc1onc(-c2ccc(F)cn2)c1CCc1ncc(C(=O)NCC(F)(F)F)s1 -US05977105,3,OB(O)c1ccccc1.OC(CCc1cccnc1)COc1cccc(Br)c1>>OC(CCc1cccnc1)COc1cccc(-c2ccccc2)c1 -US20080161366A1,1,CN.Cc1ccc(N2c3ccccc3N(CCCBr)S2(=O)=O)cc1>>CNCCCN1c2ccccc2N(c2ccc(C)cc2)S1(=O)=O -US05214191,7,CCC(C(=O)O)c1ccc([N+](=O)[O-])cc1>>CCC(C(=O)O)c1ccc(N)cc1 -US08263606B2,6,COc1ncc(CN2C(=O)C3(COc4cc5c(cc43)OCCO5)c3ccccc32)cn1>>O=C1N(Cc2cnc(O)nc2)c2ccccc2C12COc1cc3c(cc12)OCCO3 -US06184225B2,7,COC(=O)Oc1cc(Nc2ncnc3cc([N+](=O)[O-])c(OC)cc23)c(F)cc1C>>COC(=O)Oc1cc(Nc2ncnc3cc(N)c(OC)cc23)c(F)cc1C -US20110224155A1,2,N#Cc1ccsc1N.O=C=NC(=O)c1ccccc1>>N#Cc1ccsc1NC(=O)NC(=O)c1ccccc1 -US09045486B2,6,CC(C)(C)[Si](C)(C)OCCN(CC1CC1)C(=O)c1nc(CC2(c3ccccc3)CCCC2)nc(O)c1OCc1ccccc1>>O=C(c1nc(CC2(c3ccccc3)CCCC2)nc(O)c1OCc1ccccc1)N(CCO)CC1CC1 -US04395577,3,C=CC(N)=O.C=O.Cc1ccc([N+](=O)[O-])cc1>>C=CC(=O)NCc1cc([N+](=O)[O-])ccc1C -US05846995,2,CCN(CC)C1CCc2oc3ccc(N)cc3c2C1.O=C(Cl)c1ccncc1>>CCN(CC)C1CCc2oc3ccc(NC(=O)c4ccncc4)cc3c2C1 -US20110015200A1,2,CS(=O)(=O)Cl.O=C1CC[C@H](CN(CCO)Cc2ccccc2)N1>>CS(=O)(=O)OCCN(Cc1ccccc1)C[C@H]1CCC(=O)N1 -US06987114B1,1,Cc1cc(C)cc(C(=O)c2[nH]c(=O)[nH]c(=O)c2C(C)C)c1.ClCc1c2ccccc2cc2ccccc12>>Cc1cc(C)cc(C(=O)c2c(C(C)C)c(=O)[nH]c(=O)n2Cc2c3ccccc3cc3ccccc23)c1 -US05158950,2,C1COCCN1.CCOC(=O)OC(=O)C(C(=O)OC(C)C)=C1SC=CS1>>CC(C)OC(=O)C(C(=O)N1CCOCC1)=C1SC=CS1 -US08034812B2,1,Clc1ccc2nccn2n1.Nc1ccccc1O>>Nc1ccccc1Oc1ccc2nccn2n1 -US06127391,2,CN(C(=O)OC(C)(C)C)[C@@H](CN)Cc1ccccc1.CS(=O)(=O)Cl>>CN(C(=O)OC(C)(C)C)[C@@H](CNS(C)(=O)=O)Cc1ccccc1 -US20050043336A1,1,CN1CCC(Oc2cccc3ncnc(Cl)c23)CC1.Cc1cc(COc2ccc(N)cc2Cl)nn1C>>Cc1cc(COc2ccc(Nc3ncnc4cccc(OC5CCN(C)CC5)c34)cc2Cl)nn1C -US04125612,1,CC(=O)N1CCNCC1.CC(Cl)c1ccc(-c2ccc(Cl)cc2)cc1>>CC(=O)N1CCN(C(C)c2ccc(-c3ccc(Cl)cc3)cc2)CC1 -US20100130477A1,1,CC(C)(C)OC(=O)N1CCCNCC1.CC(C)=O>>CC(C)N1CCCN(C(=O)OC(C)(C)C)CC1 -US20070219182A1,1,ClCCCCBr.O=c1cc(O)c2ccccc2[nH]1>>O=c1cc(O)c2ccccc2n1CCCCCl -US05856273,2,CC(C)N=C=O.O=C1C(O)SCN1c1ccccc1>>CC(C)NC(=O)OC1SCN(c2ccccc2)C1=O -US05606054,2,CC(C)(CC(=O)O)NC(=O)OC(C)(C)C.NC1CCc2cccnc2NC1=O>>CC(C)(CC(=O)NC1CCc2cccnc2NC1=O)NC(=O)OC(C)(C)C -US20080039459A1,3,CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C.O=C(O)c1cncc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1>>O=C(O)c1cncc(-c2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)c1 -US20070232607A1,2,Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@@H](C)C(=O)O)c34)cc2C)cn1.NCCO>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@@H](C)C(=O)NCCO)c34)cc2C)cn1 -US20140371278A1,1,BrCc1ccccc1.Oc1ccc(F)c(F)c1F>>Fc1ccc(OCc2ccccc2)c(F)c1F -US06407096B1,1,COC(=O)CBr.OCCN1CCCCc2c(O)cccc21>>COC(=O)COc1cccc2c1CCCCN2CCO -US20150030704A1,6,C[Si](C)(C)C#Cc1cc(OCc2ccccc2)c(OCc2ccccc2)nn1>>C#Cc1cc(OCc2ccccc2)c(OCc2ccccc2)nn1 -US20100160324A1,1,COC(=O)c1n[nH]cc1[N+](=O)[O-].COc1ccc(CCl)cc1>>COC(=O)c1nn(Cc2ccc(OC)cc2)cc1[N+](=O)[O-] -US06177443B1,2,Clc1ccc(C2NCCc3sccc32)cc1.O=C(O)c1ccc(O)cc1>>O=C(c1ccc(O)cc1)N1CCc2sccc2C1c1ccc(Cl)cc1 -US08268822B2,1,CC(C)(C)OC(=O)N1CCC(Nc2cccc(-c3ccnc(Cl)n3)c2)CC1.COc1cc(CCN)ccc1O>>COc1cc(CCNc2nccc(-c3cccc(NC4CCN(C(=O)OC(C)(C)C)CC4)c3)n2)ccc1O -US20130040930A1,2,Cc1cnc(N2CCNCC2)c(C)c1.O=C(O)c1ccc(CCN2CCCS2(=O)=O)cc1>>Cc1cnc(N2CCN(C(=O)c3ccc(CCN4CCCS4(=O)=O)cc3)CC2)c(C)c1 -US04894458,6,CCOC(=O)c1cn(C2CC2)c2c(C)c(F)c(F)cc2c1=O>>Cc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US09073864B2,3,CCc1cnc(Cl)nc1.COC(=O)c1ccc(NC(CCC(F)(F)F)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2C)cc1>>CCc1cnc(-c2ccc(C(CCC(F)(F)F)Nc3ccc(C(=O)OC)cc3)c(C)c2)nc1 -US20100004245A1,9,BrC(Br)Br.CCOC(=O)c1cncc(-c2cnc(N)nn2)c1>>CCOC(=O)c1cncc(-c2cnc(Br)nn2)c1 -US20070000866A1,2,NCCOCCOCCNC(=O)CCCCCCCCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(O)CNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>O=C(CCCCCCCCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1)NCCOCCOCCNC(=O)CNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] -US20070078120A1,1,CI.COc1cccc(C2(CO)CCN(c3ccccc3OC)CC2)c1>>COCC1(c2cccc(OC)c2)CCN(c2ccccc2OC)CC1 -US20040181064A1,7,Cc1c(N2C(=O)[C@@H]3[C@H](O)CCN3C2=O)ccc(C#N)c1Cl>>Cc1c(N2C[C@@H]3[C@H](O)CCN3C2=O)ccc(C#N)c1Cl -US07626023B2,2,CC(C)[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C.COC(=O)[C@@H]1CCCN1>>COC(=O)C1CCCN1C(=O)C(C(C)C)N(C)C(=O)OC(C)(C)C -US05521147,10,CC1(C)Cc2c(Cl)ccc([N+](=O)[O-])c2O1.O=C1CCC(=O)N1Br>>CC1(C)Oc2c([N+](=O)[O-])ccc(Cl)c2C1Br -US06407111B1,6,CCOC(=O)c1cnc(N2CCOCC2)cc1Oc1ccccc1>>O=C(O)c1cnc(N2CCOCC2)cc1Oc1ccccc1 -US04490380,1,Clc1cccnc1Cl.SCc1ccccc1>>Clc1cccnc1SCc1ccccc1 -US20110144334A1,2,CC(C)C(=O)Cl.Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)Nc1ncc(Br)cn1>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)N(C(=O)C(C)C)c1ncc(Br)cn1 -US20100266714A1,6,COC(=O)c1cc(-c2ccc(C)cn2)cc(-c2ncccc2F)c1>>Cc1ccc(-c2cc(C(=O)O)cc(-c3ncccc3F)c2)nc1 -US20130072492A1,7,N#Cc1cccnn1>>NCc1cccnn1 -US07902248B2,7,CCCn1ccc([N+](=O)[O-])n1>>CCCn1ccc(N)n1 -US20130116243A1,6,CN1CC(=O)Nc2cc(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nc21>>CN1CC(=O)Nc2cc(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc21 -US20070259863A1,6,CCOC(=O)C1CCN(C(=O)C=Cc2ccc(Sc3cccc(NC4CCN(C)CC4)c3)c(C(F)(F)F)c2C(F)(F)F)CC1>>CN1CCC(Nc2cccc(Sc3ccc(C=CC(=O)N4CCC(C(=O)O)CC4)c(C(F)(F)F)c3C(F)(F)F)c2)CC1 -US05306719,2,CCC(=O)NC1CCN(c2ccc(N)cc2)CC1.O=C(Cl)CCBr>>CCC(=O)NC1CCN(c2ccc(NC(=O)CCBr)cc2)CC1 -US20060004003A1,9,CCn1ncc2c(-c3cncc(Br)c3)c(C=O)c(C)nc21.NO>>CCn1ncc2c(-c3cncc(Br)c3)c(C=NO)c(C)nc21 -US20110092553A1,1,COC(=O)c1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2Cc2ccc(-c3ccc(O)cc3)cc2)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)c1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2Cc2ccc(-c3ccc(Oc4ccc(C(F)(F)F)cc4)cc3)cc2)cc1 -US20060084645A1,1,CSc1ccc(N)cc1.Clc1cc(-c2ccccc2)nc(-c2ccccc2)n1>>CSc1ccc(Nc2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 -US08969345B2,1,C/C(C#N)=C1/c2ccc(CBr)cc2COc2cc(F)ccc21.FC(F)(F)c1nc2ccccc2[nH]1>>C/C(C#N)=C1/c2ccc(Cn3c(C(F)(F)F)nc4ccccc43)cc2COc2cc(F)ccc21 -US20060211706A1,6,Cc1cn(CCc2ccccc2NC(=O)OC(C)(C)C)cn1>>Cc1cn(CCc2ccccc2N)cn1 -US20070021424A1,1,CC(C)(C)OC(=O)N1CCC(CCO)CC1.Fc1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CCC(CCOc2ccc(Br)cc2)CC1 -US20150225354A1,2,CC(C)(C)OC(=O)C[C@H](NC(=O)CCc1ccc(O)cc1C1=NOC(CC(=O)OC(C)(C)C)(C(=O)OC(C)(C)C)C1)C(=O)OC(C)(C)C.N=C(N)Nc1ccc(C(=O)Cl)cc1>>CC(C)(C)OC(=O)C[C@H](NC(=O)CCc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1C1=NOC(CC(=O)OC(C)(C)C)(C(=O)OC(C)(C)C)C1)C(=O)OC(C)(C)C -US20130137865A1,2,CN(N)C(=O)OC(C)(C)C.Cn1ncc(C(=O)O)c1COc1ccc(C(F)(F)F)cc1>>CN(NC(=O)c1cnn(C)c1COc1ccc(C(F)(F)F)cc1)C(=O)OC(C)(C)C -US20070270421A1,6,COC(=O)c1cc(-c2ccc(NC(=O)OCc3ccccc3)c(F)c2)ccn1>>O=C(Nc1ccc(-c2ccnc(C(=O)O)c2)cc1F)OCc1ccccc1 -US20110207729A1,6,COC(=O)c1ccc2c(c1)C(c1ccccc1OC)=CC(C)(C)O2>>COc1ccccc1C1=CC(C)(C)Oc2ccc(C(=O)O)cc21 -US20120289522A1,3,C=CC(C)(C)C(O)c1c(C)noc1-c1ccc(-c2ccc(C3(C(=O)OCC)CC3)cc2)cc1.Ic1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C(C)(C)/C=C/c4ccccc4)cc3)cc2)CC1 -US20080085886A1,1,CCOC(=O)c1oc2ccncc2c1O.O=[N+]([O-])c1ccc(F)c(F)c1>>CCOC(=O)c1oc2ccncc2c1Oc1ccc([N+](=O)[O-])cc1F -US20040002512A1,1,CC(C)(C)OC(=O)CBr.COC(=O)C(C)(O)c1ccc(O)cc1>>COC(=O)C(C)(O)c1ccc(OCC(=O)OC(C)(C)C)cc1 -US20100120740A1,1,O=C(CCl)N1CCC1.O=C([O-])c1cc2occc2[nH]1>>O=C(OCC(=O)N1CCC1)c1cc2occc2[nH]1 -US06407066B1,2,CC(C)(C)OC(=O)[C@@H](N)Cc1ccc(O)cc1.O=C(O)[C@@H]1CCC(=O)N1Cc1ccccc1>>CC(C)(C)OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCC(=O)N1Cc1ccccc1 -US05281585,6,CC(=O)NCCC(=O)OC(C)(C)C>>CC(=O)NCCC(=O)O -US04666916,1,CN1CC[C@H]2COc3ccc(O)cc3[C@H]2C1.OCCc1ccccc1>>CN1CC[C@H]2COc3ccc(OCCc4ccccc4)cc3[C@H]2C1 -US04472586,1,O=C(O)c1ccc(O)c(I)c1.O=[N+]([O-])c1ccc(CO)c(S)c1>>O=C(O)c1ccc(O)c(Sc2cc([N+](=O)[O-])ccc2CO)c1 -US05296477,1,CN1CS(=O)c2cc(CCN)ccc21.O=C1c2ccccc2C(=O)N1CCCCBr>>CN1CS(=O)c2cc(CCNCCCCN3C(=O)c4ccccc4C3=O)ccc21 -US08349831B2,1,CN1CCCC(CCl)C1.C[C@@H](NCc1ccc(Cl)c(O)c1)c1cccc(Cl)c1>>C[C@@H](NCc1ccc(Cl)c(OCC2CCCN(C)C2)c1)c1cccc(Cl)c1 -US07576135B2,3,NS(=O)(=O)c1ccccc1Br.O=C(O)c1ccc(B(O)O)cc1>>NS(=O)(=O)c1ccccc1-c1ccc(C(=O)O)cc1 -US20050277640A1,1,N#Cc1cc(Cl)ccn1.Nc1ccc(O)c(F)c1>>N#Cc1cc(Oc2ccc(N)cc2F)ccn1 -US06022884,7,Cc1cc(Cl)ccc1Oc1ncc([N+](=O)[O-])cc1C>>Cc1cc(Cl)ccc1Oc1ncc(N)cc1C -US20050004133A1,7,O=c1[nH]c2cc([N+](=O)[O-])ccc2o1>>Nc1ccc2oc(=O)[nH]c2c1 -US20120214784A1,7,Cc1nn(-c2c(F)cccc2[N+](=O)[O-])cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12>>Cc1nn(-c2c(N)cccc2F)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12 -US07179812B2,3,Brc1cnc(I)nc1.C#CCCn1ccnn1>>Brc1cnc(C#CCCn2ccnn2)nc1 -US07456168B2,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Cc1c(Br)c(=O)n(C2CCCC2)c2nc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)C(C)(C)C4)cn3)ncc12>>C=C(OCC)c1c(C)c2cnc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)C(C)(C)C4)cn3)nc2n(C2CCCC2)c1=O -US20080004295A1,2,O=C(O)c1ccc(Nc2nc(NCC(F)(F)F)c3ccnc-3[nH]2)cc1.O=S1(=O)CCNCC1>>O=C(c1ccc(Nc2nc(NCC(F)(F)F)c3ccnc-3[nH]2)cc1)N1CCS(=O)(=O)CC1 -US08008322B2,3,CC(C)(C)OC(=O)N(Nc1nccc(I)c1C#N)C(=O)OC(C)(C)C.CC1(C)OB(c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)OC1(C)C>>CC(C)(C)OC(=O)N(Nc1nccc(-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)c1C#N)C(=O)OC(C)(C)C -US06689772B1,7,O=C(CCCc1cccs1)N1CCOCC1>>c1csc(CCCCN2CCOCC2)c1 -US05439937,6,CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(C(=O)OC)CC2>>CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(C(=O)O)CC2 -US20110237620A1,2,Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1F.O=C(O)Cc1ccsc1>>O=C(Cc1ccsc1)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1F -US07851473B2,2,COc1ccc(NC(=O)OCC(Cl)(Cl)Cl)cn1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>COc1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)cn1 -US20040092559A1,7,COC(=O)c1ccc([N+](=O)[O-])c2ccccc12>>COC(=O)c1ccc(N)c2ccccc12 -US20050070539A1,1,C1CCNC1.CC(C)NS(=O)(=O)c1ccc(Cl)c(C(=O)O)c1>>CC(C)NS(=O)(=O)c1ccc(N2CCCC2)c(C(=O)O)c1 -US20150191460A1,2,Cc1cc(N2C[C@H](C)O[C@H](C)C2)ccc1C(=O)O.Nc1cnc(Cl)c(-c2nc3ccccc3[nH]2)c1>>Cc1cc(N2C[C@H](C)O[C@H](C)C2)ccc1C(=O)Nc1cnc(Cl)c(-c2nc3ccccc3[nH]2)c1 -US04703054,2,CC1NC(C)(C)N(CC(N)=O)C1=O.O=C(O)CNC(=O)OCc1ccccc1>>CC1C(=O)N(CC(N)=O)C(C)(C)N1C(=O)CNC(=O)OCc1ccccc1 -US20070082899A1,6,CC(=O)N(C)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CCC1>>CNc1ccc2c(c1)nc(C(C)(C)C)n2CC1CCC1 -US08263606B2,1,BrCc1ccccn1.O=C1Nc2ccccc2C12COc1c(Cl)cc3c(c12)OCCO3>>O=C1N(Cc2ccccn2)c2ccccc2C12COc1c(Cl)cc3c(c12)OCCO3 -US20050004174A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(Nc1ccc2[nH]ncc2c1)OCc1ccccc1>>O=C(Nc1ccc2c(cnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1)OCc1ccccc1 -US20130259850A1,7,Cc1cccc(Cl)c1C=O>>Cc1cccc(Cl)c1CO -US20150266874A1,1,CCOC(=O)c1c[nH]nc1-c1nc2c(s1)CCC2.C[Si](C)(C)CCOCCl>>CCOC(=O)c1cn(COCC[Si](C)(C)C)nc1-c1nc2c(s1)CCC2 -US20140309193A1,6,COCCOCCOCCOCCOCCOCCOCCOCC(C)(C)C(=O)OC(C)(C)C>>COCCOCCOCCOCCOCCOCCOCCOCC(C)(C)C(=O)O -US20140296209A1,3,CN(C)c1ncc(B2OC(C)(C)C(C)(C)O2)cn1.Cc1ccc2c(c1)c1c(n2-c2cccc(Br)c2)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2-c2cccc(-c3cnc(N(C)C)nc3)c2)CCN(C)C1 -US20140343059A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(Br)c2)C(COc2cccnc2)C1>>O=C(c1cccc(Br)c1)N1CCNCC1COc1cccnc1 -US08436035B2,7,CO/N=C1\CC(C)(C)[C@H](n2cncc2C(=O)OC)c2ccccc21>>CON=C1CC(C)(C)[C@H](n2cncc2CO)c2ccccc21 -US09120761B2,7,CCc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc(C(F)(F)F)c(C#Cc2ccccc2CC(=O)OC)n1>>CCc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(=O)OC)n1 -US20030149104A1,6,CCOC(=O)C(Cc1ccc(Cc2ccccc2)c(OCCc2ccc(OS(C)(=O)=O)cc2)c1)OCC>>CCOC(Cc1ccc(Cc2ccccc2)c(OCCc2ccc(OS(C)(=O)=O)cc2)c1)C(=O)O -US05120738,6,CC1(C)OCC(C)(C)C(C(=O)NCCC(=O)OCc2ccccc2)O1>>CC1(C)OCC(C)(C)C(C(=O)NCCC(=O)O)O1 -US04160090,9,CN(C)Nc1c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c1[N+](=O)[O-].N>>CN(C)Nc1c([N+](=O)[O-])cc(C(F)(F)F)c(N)c1[N+](=O)[O-] -US08129396B2,7,Nc1cc(Cn2ccnc2)ccc1[N+](=O)[O-]>>Nc1ccc(Cn2ccnc2)cc1N -US05614544,7,CCOC(=O)/C=C/c1ccc(C=Cc2nc(-c3ccccc3)oc2C)cc1>>Cc1oc(-c2ccccc2)nc1/C=C/c1ccc(/C=C/CO)cc1 -US20060035870A1,7,CCOC(=O)c1cc2cc(-c3ccccc3)ccc2[nH]1>>OCc1cc2cc(-c3ccccc3)ccc2[nH]1 -US20140163035A1,1,CCOC(=O)c1c(Cl)cc(C)nc1Cl.CC[O-]>>CCOC(=O)c1c(OCC)cc(C)nc1Cl -US20070093484A1,2,CCOC(=O)c1nc(-c2ccc(C)cc2)c(-c2ccc(Cl)cc2)nc1Cn1ncnn1.NN1CCCCC1>>Cc1ccc(-c2nc(C(=O)NN3CCCCC3)c(Cn3ncnn3)nc2-c2ccc(Cl)cc2)cc1 -US04727067,1,ClCC1CO1.O=C(NCCO)NCc1ccccc1O>>O=C(NCCO)NCc1ccccc1OCC1CO1 -US20050159388A1,7,CCNC(=O)Nc1ncnc2c1ncn2C1OC(C=CC(=O)OC)C2OC(C=Cc3ccccc3)OC21>>CCNC(=O)Nc1ncnc2c1ncn2C1OC(CCC(=O)OC)C2OC(C=Cc3ccccc3)OC21 -US08071605B2,1,CCCO[C@@H]1CNCC[C@@H]1NC(=O)c1cc(Cl)c(C)[nH]1.COC(=O)c1sc(Cl)nc1-c1ncnn1C>>CCCO[C@H]1CN(c2nc(-c3ncnn3C)c(C(=O)OC)s2)CC[C@H]1NC(=O)c1cc(Cl)c(C)[nH]1 -US20120189546A1,6,COC(=O)[C@H](Cc1ccc(O[C@@H]2C[C@H](F)C2)cc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O[C@@H]2C[C@H](F)C2)cc1)C(=O)O -US08063234B2,8,CSCc1cc(F)cc2c(C(CCC#N)c3ccc(Cl)cc3Cl)c[nH]c12.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cc(F)cc2c(C(CCC#N)c3ccc(Cl)cc3Cl)c[nH]c12 -US04965273,9,CCOC(=O)C1CN(Cc2ccccc2)CC1O.N>>NC(=O)C1CN(Cc2ccccc2)CC1O -US04849424,1,Clc1ccnc(Cl)n1.c1c[nH]cn1>>Clc1nccc(-n2ccnc2)n1 -US20100035917A1,7,C=C(C)c1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cc3)ccnc2n1S(=O)(=O)c1ccccc1>>CC(C)c1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cc3)ccnc2n1S(=O)(=O)c1ccccc1 -US08143271B2,6,CC(C)[Si](C(C)C)(C(C)C)n1cc(Cc2cc(F)c(OCc3ccccc3)cc2F)c2cccnc21>>CC(C)[Si](C(C)C)(C(C)C)n1cc(Cc2cc(F)c(O)cc2F)c2cccnc21 -US20060252768A1,1,C1CCNC1.CC(C)(C)OC(=O)N1CCC(c2ccc(Br)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(N3CCCC3)cc2)CC1 -US20100125082A1,1,CC(C)(C)S(N)=O.N#Cc1c(F)cccc1C(=O)c1ccnc(Br)c1>>CC(C)(C)S(=O)N=C(c1ccnc(Br)c1)c1cccc(F)c1C#N -US04537984,1,CCCCOC(=O)C(C)O.O=Cc1ccc(O)cc1>>CCCCOC(=O)C(C)Oc1ccc(C=O)cc1 -US07732446B1,6,COc1cc2c(CC(=O)N(C)CCc3ccccn3)cnc(CNC(=O)OC(C)(C)C)c2cc1OC>>COc1cc2c(CC(=O)N(C)CCc3ccccn3)cnc(CN)c2cc1OC -US08618095B2,1,CC1(C)Oc2ccc(Nc3nc(Cl)ncc3F)nc2NC1=O.Nc1ccc2ccncc2c1>>CC1(C)Oc2ccc(Nc3nc(Nc4ccc5ccncc5c4)ncc3F)nc2NC1=O -US08273774B2,1,C1CSCCN1.N#Cc1ccc(Br)c(CBr)c1>>N#Cc1ccc(Br)c(CN2CCSCC2)c1 -US20120142735A1,6,COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)C(F)(F)F)ccc3F)CC2)c2cc(Cl)cc(C)c21>>COCCn1cc(C(=O)N2CCC(c3cc(CN)ccc3F)CC2)c2cc(Cl)cc(C)c21 -US20090291903A1,2,CC(=O)Cl.O=C([C@@H]1C[C@H](Oc2ccc(F)cc2)CN1)N1CCCN(C2CCC2)CC1>>CC(=O)N1C[C@@H](Oc2ccc(F)cc2)C[C@H]1C(=O)N1CCCN(C2CCC2)CC1 -US07977371B2,3,C#C[Si](C(C)C)(C(C)C)C(C)C.NC(=O)Nc1[nH]c(-c2cccc(Br)c2)cc1C(N)=O>>CC(C)[Si](C#Cc1cccc(-c2cc(C(N)=O)c(NC(N)=O)[nH]2)c1)(C(C)C)C(C)C -US08952169B2,6,CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC23CC4CC(C2)C(F)(F)C(C4)C3)cc1F>>O=C(O)c1cc(C2CC2)c(OCC23CC4CC(C2)C(F)(F)C(C4)C3)cc1F -US20070259907A1,2,COCCC(=O)Cl.Nc1cnc2cc(Br)ccc2c1O>>COCCC(=O)Nc1cnc2cc(Br)ccc2c1O -US06897224B2,1,CC(C)(CC(O)(C=O)C(F)(F)F)c1ccc(Cl)c2c1OCO2.COC(=O)c1ccc2c(N)cccc2n1>>COC(=O)c1ccc2c(N=CC(O)(CC(C)(C)c3ccc(Cl)c4c3OCO4)C(F)(F)F)cccc2n1 -US08987248B2,2,CCc1ccc(C2CC(N)CN(C(=O)C3CCCC3)C2)cc1.O=C(O)c1ccc(Cl)s1>>CCc1ccc(C2CC(NC(=O)c3ccc(Cl)s3)CN(C(=O)C3CCCC3)C2)cc1 -US20090036492A1,3,CC[Sn](CC)(CC)CC.O=Cc1c(Br)ccc2ccc(F)cc12>>CCc1ccc2ccc(F)cc2c1C=O -US05229400,2,CCCC(=O)O.Nc1ccc(C=CCN2CCC(=C3c4ccccc4C=Cc4ccccc43)CC2)cc1>>CCCC(=O)Nc1ccc(C=CCN2CCC(=C3c4ccccc4C=Cc4ccccc43)CC2)cc1 -US04371468,7,CC(=O)c1ccc2c(c1)C(c1ccccc1)=NCc1cnc(C)n1-2>>Cc1ncc2n1-c1ccc(C(C)O)cc1C(c1ccccc1)=NC2 -US05324747,2,CCCCCCCCCCN.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CCCCCCCCCCNC(=O)c1ccc([N+](=O)[O-])cc1 -US07196104B2,6,CCOC(=O)c1csc(Oc2ccccc2)n1>>O=C(O)c1csc(Oc2ccccc2)n1 -US04415571,2,CC(C)OC(=O)Cl.CC1CC(=O)NN=C1c1ccc(N)cc1>>CC(C)OC(=O)Nc1ccc(C2=NNC(=O)CC2C)cc1 -US20130109661A1,1,CC1(C)CCN(c2cccc(N)n2)C1.COC(=O)c1cccc(-c2cc(Br)c3nccn3n2)c1>>COC(=O)c1cccc(-c2cc(Nc3cccc(N4CCC(C)(C)C4)n3)c3nccn3n2)c1 -US07067534B1,1,CC(=O)c1cccc(OCCCCCCl)c1.O=C(Nc1cccc(C2CCNCC2)c1)C1CC1>>CC(=O)c1cccc(OCCCCCN2CCC(c3cccc(NC(=O)C4CC4)c3)CC2)c1 -US05409928,10,COC(=O)c1ccc(C)c(Cl)c1.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(CBr)c(Cl)c1 -US20120277208A1,1,CC(C)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1.N#Cc1cnc(Cl)cn1>>CC(C)Oc1cc(Oc2cnc(C#N)cn2)cc(C(=O)Nc2ccn(C)n2)c1 -US04001272,4,Nc1ccc(F)cc1F.O=C1OC(=O)C2=C1CCCC2>>O=C1C2=C(CCCC2)C(=O)N1c1ccc(F)cc1F -US06281354B1,3,CC(C)(C)OC(=O)N(CCCC=O)c1cc(OCc2ccccc2)c2ccccc2c1I.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)/C=C/CCCN(C(=O)OC(C)(C)C)c1cc(OCc2ccccc2)c2ccccc2c1I -US20070078122A1,2,NC[C@H]1CCCO1.O=C(O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(C(=O)N1CCC(N2CCOCC2)CC1)=Cc1ccccc1-3>>O=C(NC[C@H]1CCCO1)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(C(=O)N1CCC(N2CCOCC2)CC1)=Cc1ccccc1-3 -US04728646,1,C1CNCCN1.Clc1nc(N2CCSCC2)c2ncnc(Sc3ccccc3)c2n1>>c1ccc(Sc2ncnc3c(N4CCSCC4)nc(N4CCNCC4)nc23)cc1 -US20120245136A1,1,CC(C)O.COc1cc(C(=O)N2CCC3(CC2)CC(O)c2nn(C(C)(C)C)cc2O3)ccc1OC(C)C>>COc1cc(C(=O)N2CCC3(CC2)CC(OC(C)C)c2nn(C(C)(C)C)cc2O3)ccc1OC(C)C -US20120022059A1,3,COc1cccc(B(O)O)c1.O=C1CN(C(=O)c2cc(Br)c(-c3cccc(Cl)c3)o2)CCN1>>COc1cccc(-c2cc(C(=O)N3CCNC(=O)C3)oc2-c2cccc(Cl)c2)c1 -US08304557B2,1,O=[N+]([O-])c1cc(O)ccc1Cl.O=[N+]([O-])c1ccc(Br)cn1>>O=[N+]([O-])c1ccc(Oc2ccc(Cl)c([N+](=O)[O-])c2)cn1 -US20100094000A1,10,C=C(C)Cn1nc(C)c(Br)c1-c1ccc(F)cc1.O>>Cc1nn(CC(C)CO)c(-c2ccc(F)cc2)c1Br -US20150005232A1,2,CN1CCNCC1.O=C(O)c1cncc(Br)c1>>CN1CCN(C(=O)c2cncc(Br)c2)CC1 -US04260628,6,N=C(N)NCC1Cc2ccccc2N1Cc1ccccc1>>N=C(N)NCC1Cc2ccccc2N1 -US20110092505A1,6,CC(C)(C)OC(=O)N1CCN(c2cc([N+](=O)[O-])cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1>>O=[N+]([O-])c1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCNCC2)c1 -US20080004274A1,9,BrC(Br)(Br)Br.CCOC(=O)c1ccc(CCCO)cc1>>CCOC(=O)c1ccc(CCCBr)cc1 -US05373008,1,CC(=O)OCCN1CCN(C)C1=O.Nc1ccccc1N1CCOCC1>>CC(=O)OCCN1CCN(C)C1=Nc1ccccc1N1CCOCC1 -US08153626B2,1,CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc(-c4n[nH]c(=O)o4)cc32)cc1.CI>>Cn1nc(-c2ccc3c(c2)N(S(=O)(=O)c2ccc(C(C)(C)C)cc2)Cc2ccc(C(F)(F)F)nc2N3)oc1=O -US08536165B2,5,Cc1ccc(N)c(C(=O)O)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1ccc(NC(=O)C(F)(F)F)c(C(=O)O)c1 -US08252935B2,1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C(F)(F)F)N2)c1.FC(F)(F)c1ccc(CBr)cc1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C(F)(F)F)N2Cc2ccc(C(F)(F)F)cc2)c1 -US20030055251A1,6,CCc1ccc2c(c1)C1(CCN(Cc3ccccc3)CC1)OC2=O>>CCc1ccc2c(c1)C1(CCNCC1)OC2=O -US20090209522A1,2,COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1N.O=C(O)c1csc(Br)n1>>COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Br)n1 -US07820673B2,2,COC(C)(C)C(NC(=O)OC(C)(C)C)C(=O)O.Cc1ncc2n1C(=O)N(C1CCNCC1)C2>>COC(C)(C)C(NC(=O)OC(C)(C)C)C(=O)N1CCC(N2Cc3cnc(C)n3C2=O)CC1 -US05597841,1,COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COC(=O)c1c(Cl)ccc(O)c1Cl)C2=O.O=C(OCc1ccccc1)N1CCC(CCO)CC1>>COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COC(=O)c1c(Cl)ccc(OCCC3CCN(C(=O)OCc4ccccc4)CC3)c1Cl)C2=O -US08809525B2,3,Nc1nnc(Br)c(-c2ccc(F)cc2F)n1.OB(O)c1cccc(Cl)c1>>Nc1nnc(-c2cccc(Cl)c2)c(-c2ccc(F)cc2F)n1 -US08288419B2,7,COC(=O)c1ccc(Cn2ccc([N+](=O)[O-])n2)o1>>O=[N+]([O-])c1ccn(Cc2ccc(CO)o2)n1 -US07838543B2,2,CN(C)C1CCN(c2nc3ccc(N)cc3s2)C1.COc1ccc(/C=C/C(=O)O)cc1>>COc1ccc(C=CC(=O)Nc2ccc3nc(N4CCC(N(C)C)C4)sc3c2)cc1 -US20060089398A1,6,CCN(CC)c1ccc(NC(=O)c2c(-c3c(Cl)cccc3Cl)noc2CCCCO[Si](C)(C)C(C)(C)C)cc1>>CCN(CC)c1ccc(NC(=O)c2c(-c3c(Cl)cccc3Cl)noc2CCCCO)cc1 -US20090274652A1,2,COc1cnc(O[C@@H]2C[C@@H](C(=O)N[C@]3(C(=O)NS(=O)(=O)C4CC4)C[C@H]3CC(F)F)N(C(=O)[C@@H](N)C(C)(C)C)C2)c2cc(Cl)ccc12.O=C(N=C=S)OCC1c2ccccc2-c2ccccc21>>COc1cnc(O[C@@H]2C[C@@H](C(=O)N[C@]3(C(=O)NS(=O)(=O)C4CC4)C[C@H]3CC(F)F)N(C(=O)[C@@H](NC(=S)NC(=O)OCC3c4ccccc4-c4ccccc43)C(C)(C)C)C2)c2cc(Cl)ccc12 -US07985755B2,1,N#Cc1c(F)cccc1F.OCC1CCC(Oc2c(F)cccc2F)CC1>>N#Cc1c(F)cccc1OCC1CCC(Oc2c(F)cccc2F)CC1 -US20130005707A1,1,Brc1nc2cccc(-c3ccccc3)n2n1.Nc1ccc2cnn(C3CCCCO3)c2c1>>c1ccc(-c2cccc3nc(Nc4ccc5cnn(C6CCCCO6)c5c4)nn23)cc1 -US05998433,7,CCOC(=O)CCc1ccoc1>>OCCCc1ccoc1 -US20130116283A1,3,C1CCNC1.O=C1CCN(Cc2ccccc2)CC1.[C-]#N>>N#CC1(N2CCCC2)CCN(Cc2ccccc2)CC1 -US20070219187A1,2,O=C(O)c1ccc(F)cc1.OC1CCCNC1>>O=C(c1ccc(F)cc1)N1CCCC(O)C1 -US07709490B2,3,C#CCCCCC(=O)O.Clc1ncc(-c2ccccc2)c(-c2ccccc2)n1>>O=C(O)CCCCC#Cc1ncc(-c2ccccc2)c(-c2ccccc2)n1 -US08252723B2,4,COC(=O)CC(C(C)=O)C(=O)c1cccc(Cl)c1.NNc1cccnc1>>COC(=O)Cc1c(C)nn(-c2cccnc2)c1-c1cccc(Cl)c1 -US07696226B2,6,COC(=O)N[C@H](C(=O)NN(Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)(C)C>>COC(=O)N[C@H](C(=O)NNC[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)(C)C -US20070208046A1,6,CC(C)(C)[Si](C)(C)O[C@H]1CCN(CCOc2ccc(-n3ccc(OCc4ccc(Cl)cn4)cc3=O)cc2)C1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(OCCN2CC[C@H](O)C2)cc1 -US06034239,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1ccc2c(c1)CCO2>>CCOC(=O)/C=C/c1ccc2c(c1)CCO2 -US20070054918A1,7,C=CCN1CCN(c2ccc([N+](=O)[O-])nc2)CC1>>C=CCN1CCN(c2ccc(N)nc2)CC1 -US20080045530A1,6,COC(=O)[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1CCc1ccc2ccccc2c1>>CC(C)(C)OC(=O)N1C[C@H](C(=O)O)[C@@H](CCc2ccc3ccccc3c2)C1 -US20090286809A1,1,COc1cccc(N)c1.Cc1nc(Cl)cc(Nc2cccc(O)c2)n1>>COc1cccc(Nc2cc(Nc3cccc(O)c3)nc(C)n2)c1 -US20060178405A1,1,COC(=O)c1cc2ccc(O)cc2oc1=O.OCCc1ccccc1>>COC(=O)c1cc2ccc(OCCc3ccccc3)cc2oc1=O -US07569725B2,2,COc1ccc(C(=O)Nc2ccccc2C(=O)O)cc1Cl.NCCc1ccccc1>>COc1ccc(C(=O)Nc2ccccc2C(=O)NCCc2ccccc2)cc1Cl -US20050239826A1,1,CCCBr.OC1(CNCCOc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)CC1>>CCCN(CCOc1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1)CC1(O)CC1 -US20110086843A1,3,CC(=O)Nc1nc(C)c(I)s1.CCCC[Sn](CCCC)(CCCC)c1cccs1>>CC(=O)Nc1nc(C)c(-c2cccs2)s1 -US06998423B2,6,CCCCc1ccc(CN(CCCCCCC(=O)OCC)S(C)(=O)=O)cc1>>CCCCc1ccc(CN(CCCCCCC(=O)O)S(C)(=O)=O)cc1 -US07507740B2,1,CS(=O)(=O)OCCOCCOC(=O)c1ccccc1.CSc1ncnc2cn[nH]c12>>CSc1ncnc2cnn(CCOCCOC(=O)c3ccccc3)c12 -US20140155428A1,6,COc1ccc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2F)cc1OC>>COc1ccc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2ccc(N)cc2F)cc1OC -US08003685B2,1,COC(=O)c1sc(C#CC(C)(C)C)cc1N.O=C1CCC(n2ccnn2)CC1>>COC(=O)c1sc(C#CC(C)(C)C)cc1NC1CCC(n2ccnn2)CC1 -US20140243526A1,7,CC1=CC[C@H](CCC(C)C=O)C1(C)C>>CC1=CC[C@H](CCC(C)CO)C1(C)C -US04689349,3,CC[Mg+].O=CCCCCC1C=CCC1>>CCC(O)CCCCC1C=CCC1 -US20150239900A1,3,Cc1nc(N2CCN(C(=O)OC(C)(C)C)C(C(N)=O)C2)c2cc(Br)c(Cl)cc2n1.OB(O)c1ccc(Cl)cc1>>Cc1nc(N2CCN(C(=O)OC(C)(C)C)C(C(N)=O)C2)c2cc(-c3ccc(Cl)cc3)c(Cl)cc2n1 -US20140296203A1,1,COC[C@@H](NC(N)=O)c1ccccc1.Cn1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc(Cl)ncc23)cn1>>COC[C@@H](NC(=O)Nc1cc2c(cn1)c(-c1cnn(C)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1 -US20020161006A1,1,COC(=O)CC1=C(C(=O)OC)C(c2c(Cl)cccc2Cl)C(C(=O)OC)=C(CCc2ccccc2O)N1.O=C1CCCN1CCO>>COC(=O)CC1=C(C(=O)OC)C(c2c(Cl)cccc2Cl)C(C(=O)OC)=C(CCc2ccccc2OCCN2CCCC2=O)N1 -US07582761B2,6,CC(C)(C)OC(=O)N1CCN(c2ncccc2Cl)CC1>>Clc1cccnc1N1CCNCC1 -US20050222151A1,8,OCc1cncc(Br)c1>>O=Cc1cncc(Br)c1 -US20070249620A1,2,COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCC(C(=O)O)CC2)cc1.Cc1cccc(Cl)c1N>>COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCC(C(=O)Nc3c(C)cccc3Cl)CC2)cc1 -US20100075976A1,2,CNCC(OC)OC.Cn1cc(S(=O)(=O)Cl)cn1>>COC(CN(C)S(=O)(=O)c1cnn(C)c1)OC -US07528136B2,2,COc1cccc(C(=O)Cl)c1.N#Cc1ccccc1N1CCN(C(=O)C2CC(N)CN2Cc2ccccc2)CC1>>COc1cccc(C(=O)N[C@H]2C[C@@H](C(=O)N3CCN(c4ccccc4C#N)CC3)N(Cc3ccccc3)C2)c1 -US20110097269A1,2,COc1ccc(OCCO)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1.CS(=O)(=O)Cl>>COc1ccc(OCCOS(C)(=O)=O)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1 -US04738970,8,COc1ccc2nc(SC3CCCc4cc(C)cnc43)[nH]c2c1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2nc(S(=O)C3CCCc4cc(C)cnc43)[nH]c2c1 -US06153609,6,COc1ccc(S(=O)(=O)N(CCC(=O)N2CCN(CCO)CC2)C(C(=O)OCc2ccccc2)C(C)C)cc1>>COc1ccc(S(=O)(=O)N(CCC(=O)N2CCN(CCO)CC2)C(C(=O)O)C(C)C)cc1 -US20120208810A1,1,Fc1ccc(I)cc1.O=c1cc(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2>>O=c1cc(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2c1ccc(F)cc1 -US20140213586A1,6,COc1cncc(NC(C(=O)c2c[nH]c3ccc(CCCOC(C)=O)cc23)c2ccc(F)cc2)c1>>COc1cncc(NC(C(=O)c2c[nH]c3ccc(CCCO)cc23)c2ccc(F)cc2)c1 -US20060241273A1,5,CC(=O)C(Cl)Cl.SCCS>>CC1(C(Cl)Cl)SCCS1 -US20150209336A1,3,CCOC(=O)c1nc(Br)c2snc(-c3ccc(Cl)cc3)c2c1O.OB(O)Cc1ccccc1>>CCOC(=O)c1nc(Cc2ccccc2)c2snc(-c3ccc(Cl)cc3)c2c1O -US08673942B2,6,CCOC(=O)CC1CN=C(c2cc3cc(Oc4ccc(S(C)(=O)=O)cc4)cc(OC(C)CO[Si](c4ccccc4)(C(C)(C)C)C(C)(C)C)c3[nH]2)S1>>CC(CO[Si](c1ccccc1)(C(C)(C)C)C(C)(C)C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc2cc(C3=NCC(CC(=O)O)S3)[nH]c12 -US20140243302A1,9,[N-]=[N+]=N[C@@H]1CO[C@@H]1COCc1ccccc1>>N[C@@H]1CO[C@@H]1COCc1ccccc1 -US08129376B2,2,Cc1nnc(-c2ccc(C(=O)O)cc2)o1.NCC(=O)N1CCC(Oc2ccccc2Cl)CC1>>Cc1nnc(-c2ccc(C(=O)NCC(=O)N3CCC(Oc4ccccc4Cl)CC3)cc2)o1 -US20060199829A1,1,COC(=O)c1ccc(Cl)nc1.c1ccc2c3c([nH]c2c1)CNCC3>>COC(=O)c1ccc(N2CCc3c([nH]c4ccccc34)C2)nc1 -US20100261678A1,3,O=C(O)c1cc(Cl)nc(-c2ccccc2)n1.OB(O)c1ccsc1>>O=C(O)c1cc(-c2ccsc2)nc(-c2ccccc2)n1 -US05387710,1,CI.COC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc1ccccc1>>COC(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)OCc1ccccc1 -US20120108568A1,2,NC[C@H](O)CO.O=C(O)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12>>O=C(NC[C@H](O)CO)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12 -US07964732B2,6,COC(=O)c1ccc2cc(C(C)(C)C)ccc2c1>>CC(C)(C)c1ccc2cc(C(=O)O)ccc2c1 -US20090264482A1,1,Cc1cc2c(C(F)(F)F)c(C#N)ccc2[nH]1.FC(F)(F)c1cc(-c2cc(CCl)no2)cc(C(F)(F)F)c1>>Cc1cc2c(C(F)(F)F)c(C#N)ccc2n1Cc1cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)on1 -US04105767,2,COC(=O)Cl.Nc1cnc2ccc(Sc3ccccn3)cn12>>COC(=O)Nc1cnc2ccc(Sc3ccccn3)cn12 -US20130018033A1,2,CCCS(=O)(=O)N(Cc1ccc(OC)cc1)c1ccc(F)c(N)c1OC.O=C(Cl)c1cccc2c(Cl)ncnc12>>CCCS(=O)(=O)N(Cc1ccc(OC)cc1)c1ccc(F)c(NC(=O)c2cccc3c(Cl)ncnc23)c1OC -US06348478B1,5,COc1cccc(CCN)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cccc(CCNC(=O)C(F)(F)F)c1 -US20020173646A1,6,COc1cc2c(Nc3ccc(C)c(OC(C)=O)c3)ncnc2cc1OCc1ccccc1>>COc1cc2c(Nc3ccc(C)c(OC(C)=O)c3)ncnc2cc1O -US05470845,3,Brc1ccc(I)cc1.Brc1ccc2ccccc2c1>>Brc1ccc(-c2ccc3ccccc3c2)cc1 -US06610747B2,1,C[S-].O=[N+]([O-])c1ccc(F)c(Cl)c1>>CSc1ccc([N+](=O)[O-])cc1Cl -US20110288066A1,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CC(C)S(=O)(=O)c1cc(Br)ccc1C(=O)N1CCOCC1>>CC(C)S(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)ccc1C(=O)N1CCOCC1 -US07001897B2,2,CN(CCNC(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)c1csc(N2CC(O)C2)n1.CS(=O)(=O)Cl>>CN(CCNC(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)c1csc(N2CC(OS(C)(=O)=O)C2)n1 -US20030105089A1,3,C#C[Si](C)(C)C.OCc1cc(I)c(O)c(Cl)n1>>C[Si](C)(C)C#Cc1cc(CO)nc(Cl)c1O -US20100286119A1,7,O=[N+]([O-])c1ccc(N2CC3CC3C2)nc1>>Nc1ccc(N2CC3CC3C2)nc1 -US07485661B2,7,COC(=O)c1cc([N+](=O)[O-])c(C#N)s1>>COC(=O)c1cc(N)c(C#N)s1 -US04846875,3,C[Mg+].O=Cc1ccc(F)cc1Cl>>CC(O)c1ccc(F)cc1Cl -US06489324B2,1,C[C@@H]([C@H](COCc1ccccc1)NC(=O)OC(C)(C)C)N(CCOS(C)(=O)=O)S(C)(=O)=O>>C[C@H]1[C@H](COCc2ccccc2)N(C(=O)OC(C)(C)C)CCN1S(C)(=O)=O -US08476290B2,1,CCOC(=O)C1CC2(CCN(C(=O)OC(C)(C)C)CC2)CN1.O=Cc1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1>>CCOC(=O)C1CC2(CCN(C(=O)OC(C)(C)C)CC2)CN1Cc1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1 -US05990101,7,CC(C)(C)OC(=O)NCc1ncc(C=O)s1>>CC(C)(C)OC(=O)NCc1ncc(CO)s1 -US08546376B2,7,COC(=O)c1ccc2cnn(S(=O)(=O)N(C)C)c2c1OC>>COc1c(CO)ccc2cnn(S(=O)(=O)N(C)C)c12 -US20130274483A1,1,FC(F)(F)c1cccnc1CBr.O=C1Nc2ccccc2[C@]12COc1cc3c(cc12)OCCO3>>O=C1N(Cc2ncccc2C(F)(F)F)c2ccccc2[C@]12COc1cc3c(cc12)OCCO3 -US20120309739A1,6,CCn1c(NCCO)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2c1=O>>CCn1c(NCCO)nc2oc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)c2c1=O -US05177087,1,C1CCNCC1.CC(=O)N1CCCC(C(=O)c2ccc(F)cc2)C1>>CC(=O)N1CCCC(C(=O)c2ccc(N3CCCCC3)cc2)C1 -US20120208798A1,5,CC(=O)N1c2ccc(-c3ccc(CN4CCCCC4)cc3)cc2[C@H](N)C[C@@H]1C.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)N1c2ccc(-c3ccc(CN4CCCCC4)cc3)cc2[C@H](NC(=O)OC(C)(C)C)C[C@@H]1C -US04787930,2,CC(=O)O.Nc1ccnn1-c1c(F)c(F)c(C(F)(F)F)c(F)c1F>>CC(=O)Nc1ccnn1-c1c(F)c(F)c(C(F)(F)F)c(F)c1F -US20140228405A1,2,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(N)cc1.O=C(O)c1cccc(N2CCCCC2=O)c1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(NC(=O)c2cccc(N3CCCCC3=O)c2)cc1 -US08258134B2,6,COC(=O)C(CC1CCCC1)n1ncc(OCC2CCCC2)cc1=O>>O=C(O)C(CC1CCCC1)n1ncc(OCC2CCCC2)cc1=O -US06300344B1,1,CC(NC1CCCc2c(O)cccc21)c1nc(-c2ccccc2)c(-c2ccccc2)o1.CCOC(=O)CBr>>CCOC(=O)COc1cccc2c1CCCC2NC(C)c1nc(-c2ccccc2)c(-c2ccccc2)o1 -US20140249133A1,6,CCOc1cc(F)c(Cn2nc(-c3ncc(OCCNC(=O)OC(C)(C)C)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1>>CCOc1cc(F)c(Cn2nc(-c3ncc(OCCN)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1 -US20110124636A1,2,NC[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)c1nc(N)sc1-c1cccc(F)c1.O=C(O)c1cccc2ncccc12>>Nc1nc(C(=O)N2[C@H](CNC(=O)c3cccc4ncccc34)C[C@@H]3C[C@@H]32)c(-c2cccc(F)c2)s1 -US04110455,1,CNC.O=c1[nH]nc2n1-c1ccc(Cl)nc1C(c1ccccc1Cl)=NC2>>CN(C)c1ccc2c(n1)C(c1ccccc1Cl)=NCc1n[nH]c(=O)n1-2 -US20090181942A1,7,COc1cccc(C(=O)c2cc(Cl)ccc2N)c1C>>COc1cccc(C(O)c2cc(Cl)ccc2N)c1C -US20080287466A1,2,COc1cccc(CC(=O)O)c1.NC1=c2ccoc2=NCN1c1ccc(N)cc1>>COc1cccc(CC(=O)Nc2ccc(N3CN=c4occc4=C3N)cc2)c1 -US20150073011A1,2,C=CCON1C(=O)N2C[C@H]1C=C(C)[C@H]2C(=O)O.CC(C)(C)OC(=O)N1CCC(N)CC1>>C=CCON1C(=O)N2C[C@H]1C=C(C)[C@H]2C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 -US08183374B2,6,CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2F)CC1>>Fc1ccccc1OCCN1CCNCC1 -US06638929B2,1,N#Cc1cnc2c(oc3ccccc32)c1Cl.Nc1ccc(Oc2ccccc2)cc1>>N#Cc1cnc2c(oc3ccccc32)c1Nc1ccc(Oc2ccccc2)cc1 -US20110112158A1,6,CCOC(=O)CN(CCOC)c1noc2ccc(COc3ccc(-c4cc(F)c(F)cc4OC)cc3)cc12>>COCCN(CC(=O)O)c1noc2ccc(COc3ccc(-c4cc(F)c(F)cc4OC)cc3)cc12 -US06235771B1,6,COC(=O)C1=Cc2cc(-c3ccc(N4CCCC4)cc3)ccc2S(=O)(=O)CC1>>O=C(O)C1=Cc2cc(-c3ccc(N4CCCC4)cc3)ccc2S(=O)(=O)CC1 -US20090239860A1,1,CCOC(=O)c1ccc(Cl)nc1.OCc1cccc(O)c1>>CCOC(=O)c1ccc(Oc2cccc(CO)c2)nc1 -US20150209336A1,2,CCOC(=O)c1nc(-c2ccc(OC)cc2)c2snc(-c3ccc(Cl)cc3)c2c1O.NCC(=O)O>>COc1ccc(-c2nc(C(=O)NCC(=O)O)c(O)c3c(-c4ccc(Cl)cc4)nsc23)cc1 -US20090324581A1,6,CC(C)(C)OC(=O)NC(C)(C)C(=O)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21>>CC(C)(N)C(=O)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21 -US20070179178A1,1,Cc1onc(-c2ccccc2)c1-c1cn2cc(I)ccc2n1.c1c[nH]cn1>>Cc1onc(-c2ccccc2)c1-c1cn2cc(-n3ccnc3)ccc2n1 -US05124326,3,N#CCc1ccccc1.O=C(Cl)CCl>>N#CCc1ccc(C(=O)CCl)cc1 -US20150265612A1,2,FC(F)(F)c1cc(Nc2ccccn2)ccn1.O=C(Cl)C1(c2ccc3c(c2)OCO3)CC1>>O=C(N(c1ccnc(C(F)(F)F)c1)c1ccccn1)C1(c2ccc3c(c2)OCO3)CC1 -US06110962,9,NC(=O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br>>N#C[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br -US20140088084A1,7,CCOC(=O)C(NC(=O)OC(C)(C)C)(c1cccc(Br)c1)C(F)(F)F>>CC(C)(C)OC(=O)NC(CO)(c1cccc(Br)c1)C(F)(F)F -US08071592B2,1,OCCOc1cc(Cl)nnc1Cl>>Clc1cc2c(nn1)OCCO2 -US20090155209A1,1,C=CCCCCC[C@H](N)C(=O)O.Fc1ccc(I)cc1>>C=CCCCCC[C@H](Nc1ccc(F)cc1)C(=O)O -US20050256311A1,1,COCCN(C(C)(C)C)S(=O)(=O)c1ccc(I)cc1.Cc1ncc(-c2ccnc(N)n2)n1CC1CC1>>COCCN(C(C)(C)C)S(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3CC3CC3)n2)cc1 -US20140243324A1,7,O=[N+]([O-])c1ccc2c(Br)cn(S(=O)(=O)c3ccccc3)c2c1>>Nc1ccc2c(Br)cn(S(=O)(=O)c3ccccc3)c2c1 -US20110124633A1,3,C=CC(=O)OC(C)(C)C.CCOC(=O)CN1CC(=O)Nc2ncc(Br)cc2C1>>CCOC(=O)CN1CC(=O)Nc2ncc(/C=C/C(=O)OC(C)(C)C)cc2C1 -US08853193B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC(O)CN>>CCC(O)CNC(=O)OC(C)(C)C -US04906768,2,CC(=NO)c1cccc(N)c1.O=C(Cl)OCc1ccccc1>>CC(=NO)c1cccc(NC(=O)OCc2ccccc2)c1 -US08242280B2,3,COc1ccccc1-c1nn(COCC[Si](C)(C)C)c2ncc(B3OC(C)(C)C(C)(C)O3)cc12.Cc1cccnc1C(O)c1cccc(Br)c1>>COc1ccccc1-c1nn(COCC[Si](C)(C)C)c2ncc(-c3cccc(C(O)c4ncccc4C)c3)cc12 -US08022072B2,1,CCCOCCl.COC(=O)c1ccccc1O>>CCCOCOc1ccccc1C(=O)OC -US08841296B2,1,ClCc1cnc(Cl)s1.OCC1COC2(CCN(CCc3ccccc3)CC2)O1>>Clc1ncc(COCC2COC3(CCN(CCc4ccccc4)CC3)O2)s1 -US20150166480A1,6,COC(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)F)CC3)cn2)cc1>>CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)O)cc3)nc2)CC1 -US20150056141A1,3,CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(Br)ccc12.OB(O)c1ccncc1>>CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(-c3ccncc3)ccc12 -US20090076026A1,1,NCc1ccc(O)cc1.O=C(Nc1ccccc1-c1ccccc1)OC1CCN(CCCN2CCN(CCCO)C2=O)CC1>>O=C(Nc1ccccc1-c1ccccc1)OC1CCN(CCCN2CCN(CCCNCc3ccc(O)cc3)C2=O)CC1 -US05620971,8,OCCCCc1ccccc1>>O=CCCCc1ccccc1 -US20070249686A1,6,CCOC(=O)CNc1ccc(Cl)cc1-n1ccc2cc(OC)ccc21>>COc1ccc2c(ccn2-c2cc(Cl)ccc2NCC(=O)O)c1 -US20040053931A1,3,Cc1noc(C)c1B(O)O.O=S(=O)(Oc1ccnc2[nH]ccc12)C(F)(F)F>>Cc1noc(C)c1-c1ccnc2[nH]ccc12 -US20100137610A1,7,CCOC(=O)CN(c1cccc2cc(C3=NCC(CN4CCOCC4)S3)[nH]c12)S(=O)(=O)c1cccs1>>O=S(=O)(c1cccs1)N(CCO)c1cccc2cc(C3=NCC(CN4CCOCC4)S3)[nH]c12 -US20140288123A1,6,COC(=O)c1ccc(C(C)Oc2ccc(C)cc2)cc1>>Cc1ccc(OC(C)c2ccc(C(=O)O)cc2)cc1 -US06258824B1,1,CC(C)CBr.CCOc1cccc(-c2cc(=O)[nH]c3ccc(C(O)(c4ccc(Cl)nc4)c4cncn4C)cc23)c1>>CCOc1cccc(-c2cc(=O)n(CC(C)C)c3ccc(C(O)(c4ccc(Cl)nc4)c4cncn4C)cc23)c1 -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)c1cc(F)ccc1F>>Cc1nc(NC(=O)c2cc(F)ccc2F)sc1C(=O)NCc1ccccc1 -US05556909,1,CC(C)C1NS(=O)(=O)N(CCl)C1=O.O=C(O)c1c(Cl)cccc1Cl>>CC(C)C1NS(=O)(=O)N(COC(=O)c2c(Cl)cccc2Cl)C1=O -US20120022056A1,1,Cc1ccc2c(N3CCNCC3)cccc2n1.O=CCc1c(F)ccc(Br)c1O>>Cc1ccc2c(N3CCN(CCc4c(F)ccc(Br)c4O)CC3)cccc2n1 -US07652061B2,1,CC(=O)Oc1cccc(O)c1.Cc1oc(-c2ccccc2)nc1CCl>>CC(=O)Oc1cccc(OCc2nc(-c3ccccc3)oc2C)c1 -US20100197634A1,6,COc1nccc2c(Nc3c(Cl)cc(C#C[Si](C)(C)C)cc3Cl)nc3ccncc3c12>>C#Cc1cc(Cl)c(Nc2nc3ccncc3c3c(OC)nccc23)c(Cl)c1 -US20140315908A1,3,CCN1C(=O)CNc2ncc(B3OC(C)(C)C(C)(C)O3)nc21.Cc1nc(-c2ncn(C3CCCCO3)n2)ccc1Br>>CCN1C(=O)CNc2ncc(-c3ccc(-c4ncn(C5CCCCO5)n4)nc3C)nc21 -US20090156598A1,1,CI.Clc1cccc(Cl)c1Nc1nc2c(Cl)ncnc2[nH]1>>Cn1c(Nc2c(Cl)cccc2Cl)nc2c(Cl)ncnc21 -US20110281870A1,1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)N[C@H]1CC[C@@H]2CNC[C@H]12.FC(F)(F)c1ccnc(Br)c1>>CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)N[C@H]1CC[C@@H]2CN(c3cc(C(F)(F)F)ccn3)C[C@H]12 -US20100279990A1,3,C#CCCCO.CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(I)cc21>>CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(C#CCCCO)cc21 -US20100279990A1,3,CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(I)cc21>>I -US20150175648A1,1,CS(=O)(=O)OC1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@]1(F)Cl.O=c1cc[nH]c(=O)[nH]1>>O=C(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1OC(=O)c1ccccc1)c1ccccc1 -US07893058B2,1,Brc1ncc(Br)n2ccnc12.CN(C)Cc1cn(-c2ccc(N)cc2)nn1>>CN(C)Cc1cn(-c2ccc(Nc3ncc(Br)n4ccnc34)cc2)nn1 -US05223623,2,CN1CCN(c2ccccc2)CC1CN.CS(=O)(=O)Nc1ccc(C(=O)Cl)cc1>>CN1CCN(c2ccccc2)CC1CNC(=O)c1ccc(NS(C)(=O)=O)cc1 -US04680287,2,CCCCCCCCCCCCCCCCCC(=O)Cl.CCCCCCCCCCCCCCCCCCNC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O>>CCCCCCCCCCCCCCCCCCN(C(=O)CCCCCCCCCCCCCCCCC)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O -US04242507,2,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.CCOC(=O)CN>>CCOC(=O)CNC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C -US20050148627A1,6,CCOC(=O)C1=Cc2c(Cl)c(OC)cc(Cl)c2OC1C(F)(F)F>>COc1cc(Cl)c2c(c1Cl)C=C(C(=O)O)C(C(F)(F)F)O2 -US20150166512A1,1,Cc1ccc(Cl)cc1-c1c[nH]cc1C#N.Clc1ncnn2cccc12>>Cc1ccc(Cl)cc1-c1cn(-c2ncnn3cccc23)cc1C#N -US08592444B2,6,COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3c[nH]c4cc(F)ccc34)CC1)O2>>O=C(O)/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3c[nH]c4cc(F)ccc34)CC1)O2 -US07968572B2,6,COC(=O)C1OC(C)(C)OC1C>>CC1OC(C)(C)OC1C(=O)O -US20140154499A1,7,O=C(O)CCCCCCCCCCCCCCBr>>OCCCCCCCCCCCCCCCBr -US07098335B2,2,NCc1cccs1.O=C(O)c1cc2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)n2n1>>O=C(NCc1cccs1)c1cc2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)n2n1 -US20110124597A1,1,O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O.OB1OCc2ccc(OCCCBr)cc21>>O=C(O)c1cn(C2CC2)c2cc(N3CCN(CCCOc4ccc5c(c4)B(O)OC5)CC3)c(F)cc2c1=O -US20140162971A1,7,CCS(=O)(=O)c1ccc(OC2CCC(=O)CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1>>CCS(=O)(=O)c1ccc(O[C@@H]2CC[C@H](O)CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 -US20070254867A1,1,COc1cc(Cl)ccc1I.c1c[nH]cn1>>COc1cc(Cl)ccc1-n1ccnc1 -US20040192686A1,1,N#CCCN.[O-][n+]1nc(Cl)nc2ccccc21>>N#CCCNc1nc2ccccc2[n+]([O-])n1 -US03954994,6,O=C(OCc1ccccc1)c1cc(C(F)(F)F)cc(S(=O)(=O)Cc2ccccc2)c1>>O=C(O)c1cc(C(F)(F)F)cc(S(=O)(=O)Cc2ccccc2)c1 -US20040133008A1,1,O=[N+]([O-])c1ccc(F)cc1.OCCn1cccn1>>O=[N+]([O-])c1ccc(OCCn2cccn2)cc1 -US20150025068A1,2,COC(=O)c1ccc(N)cc1O.O=S(=O)(Cl)c1cccc(OC(F)(F)F)c1>>COC(=O)c1ccc(NS(=O)(=O)c2cccc(OC(F)(F)F)c2)cc1O -US20110003859A1,1,Brc1ccccn1.Nc1ccc([N+](=O)[O-])cn1>>O=[N+]([O-])c1ccc(Nc2ccccn2)nc1 -US20120190677A1,6,COC(=O)c1ccc2c(c1)NC(c1cccc(N3CCOCC3)c1)CC2(C)C>>CC1(C)CC(c2cccc(N3CCOCC3)c2)Nc2cc(C(=O)O)ccc21 -US20100216813A1,1,Cc1ccccc1CN(c1ccc(C#N)c(Cl)c1)[C@H]1CCNC1.O=Cc1ccc(O)c(C(=O)O)c1>>Cc1ccccc1CN(c1ccc(C#N)c(Cl)c1)[C@H]1CCN(Cc2ccc(O)c(C(=O)O)c2)C1 -US04091023,2,CO.O=C(O)c1ccc(Cl)cc1Oc1cccc(C(F)(F)F)c1>>COC(=O)c1ccc(Cl)cc1Oc1cccc(C(F)(F)F)c1 -US05824691,7,COC(=O)c1cc([N+](=O)[O-])c(N2CCCCC2)c(S(C)(=O)=O)c1>>COC(=O)c1cc(N)c(N2CCCCC2)c(S(C)(=O)=O)c1 -US20080181866A1,6,COC(=O)C1COC(c2ccncc2)N1C(=O)OCc1ccccc1>>O=C(O)C1CO[C@@H](c2ccncc2)N1C(=O)OCc1ccccc1 -US05670675,8,CC(=O)N[C@H](C(=O)N[C@H](C(=O)NC(Cc1ccccc1)C(O)C(Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)C(C)C)C(C)C)C(C)C>>CC(=O)N[C@H](C(=O)N[C@H](C(=O)NC(Cc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)C(C)C)C(C)C)C(C)C -US20110257208A1,1,CC(=O)C1CCC1.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>CC(C1CCC1)N1Cc2ncnc(Nc3cnc4ccccc4c3)c2C1 -US20020045747A1,1,N.O=Cc1cccc(-c2ccccc2)c1>>NCc1cccc(-c2ccccc2)c1 -US20100075968A1,1,CN1C(=O)NCC1C(=O)NCc1ccc(F)c(F)c1Cl.Cc1cc(Br)ccn1>>Cc1cc(N2CC(C(=O)NCc3ccc(F)c(F)c3Cl)N(C)C2=O)ccn1 -US08927719B2,9,CC1=Nc2ncc(Cl)cc2C1(C)C>>CC1=Nc2ncccc2C1(C)C -US06740647B1,9,N#Cc1csc(C=O)c1.NO>>N#Cc1csc(C=NO)c1 -US20090105242A1,3,COc1cc(B(O)O)ccn1.O=C(NCc1cccnc1)c1ccc(Nc2ccc(Cl)n3ncnc23)cc1>>COc1cc(-c2ccc(Nc3ccc(C(=O)NCc4cccnc4)cc3)c3ncnn23)ccn1 -US20080249127A1,3,CN1C2CCC1CC(OC(=O)Nc1ccccc1Br)C2.OB(O)c1ccccc1>>CN1C2CCC1CC(OC(=O)Nc1ccccc1-c1ccccc1)C2 -US20120101078A1,2,Nc1cnc(-c2cc(F)cc(F)c2)cn1.O=C(O)[C@H]1CC[C@@H](N2CCOCC2=O)CC1>>O=C(Nc1cnc(-c2cc(F)cc(F)c2)cn1)[C@H]1CC[C@@H](N2CCOCC2=O)CC1 -US07323587B2,6,COC(=O)C=Cc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1>>O=C(O)C=Cc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1 -US20120114765A1,7,CC(=O)c1cc([N+](=O)[O-])c(Sc2ccc(Cl)cc2Cl)s1>>CC(=O)c1cc(N)c(Sc2ccc(Cl)cc2Cl)s1 -US04276305,2,C#CC(O)c1ccc2ccccc2c1.O=C(O)C1CC1>>C#CC(OC(=O)C1CC1)c1ccc2ccccc2c1 -US05344843,6,CCOC(=O)C(=O)c1ccc(OCC(=O)N2CCN(c3ccccc3)CC2)cc1>>O=C(O)C(=O)c1ccc(OCC(=O)N2CCN(c3ccccc3)CC2)cc1 -US08680132B2,1,C=O.CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@@H]2CC[C@@H](O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12>>CN1[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@@H](c2cccc(Cl)c2F)[C@@H]1C(=O)NC1CCC(O)CC1 -US05036075,1,C1=C(c2ccccc2)CCNC1.O=S1(=O)c2cccc3cccc(c23)N1CCCl>>O=S1(=O)c2cccc3cccc(c23)N1CCN1CC=C(c2ccccc2)CC1 -US20130274469A1,2,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.NC1CCC1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCC2)cn1 -US04824846,1,Cc1cc(-c2ccccc2)nc(Cl)c1C#N.Oc1ccc(N2CCNCC2)cc1>>Cc1cc(-c2ccccc2)nc(N2CCN(c3ccc(O)cc3)CC2)c1C#N -US20030236288A1,1,CC1(C)CC(O)CC(C)(C)C1.O=[N+]([O-])c1ccc(F)cc1>>CC1(C)CC(Oc2ccc([N+](=O)[O-])cc2)CC(C)(C)C1 -US20080269210A1,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.OCCOCCNc1ccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)cc1>>Nc1ncc(-c2nc(N3CCOCC3)c3sc(-c4ccc(NCCOCCO)cc4)cc3n2)cn1 -US06384051B1,1,C#Cc1cccc(N)c1.COCCOc1ccc2ncc(C#N)c(Cl)c2c1OCCOC>>C#Cc1cccc(Nc2c(C#N)cnc3ccc(OCCOC)c(OCCOC)c23)c1 -US06303793B1,3,C#CC1(O)CCCC1.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CC3(O)CCCC3)c21 -US07935715B2,6,CCOC(=O)C1(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1>>O=C(O)C1(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1 -US08003649B2,1,C[C@H]1CN(c2ccc3nnc(C(F)(F)F)n3n2)CCN1.O=Cc1cccnc1>>C[C@H]1CN(c2ccc3nnc(C(F)(F)F)n3n2)CCN1Cc1cccnc1 -US20140206680A1,3,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1nc(Cl)c2c(c1F)CN(C(=O)OC(C)(C)C)C2=O.Cc1ccn2ncc(B3OC(C)(C)C(C)(C)O3)c2c1>>Cc1ccn2ncc(-c3nc(N[C@@H]4CCCC[C@@H]4NC(=O)OC(C)(C)C)c(F)c4c3C(=O)N(C(=O)OC(C)(C)C)C4)c2c1 -US20090298836A1,2,CC(C)(C)[Si](C)(C)OC/C=C/C(=O)O.O=C1N[C@@H](c2ccccc2)CO1>>CC(C)(C)[Si](C)(C)OC/C=C/C(=O)N1C(=O)OC[C@@H]1c1ccccc1 -US20090221555A1,1,CCN1CCN(CC)c2cc(N)ccc2C1.Clc1ncc(Cl)c(Nc2ccccc2-n2cccn2)n1>>CCN1CCN(CC)c2cc(Nc3ncc(Cl)c(Nc4ccccc4-n4cccn4)n3)ccc2C1 -US04567265,3,CC(C)CC=O.CCOC(=O)CC#N>>CCOC(=O)/C(C#N)=C/CC(C)C -US06174885B1,2,CCCCCCCCCCCCCCCCCCN=C=O.O=C(NCCN1CCCCC1)C1CC=CCC1CO>>CCCCCCCCCCCCCCCCCCNC(=O)OCC1CC=CCC1C(=O)NCCN1CCCCC1 -US20080255078A1,3,CCC(=O)c1ccc(F)c(Br)c1.O=C(c1ccc(O)cc1)c1ccc(O)cc1>>CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(F)c(Br)c1 -US20070135442A1,6,CCOC(=O)c1cc(=O)c2cc(OC)cc(N3CCN(CC(F)(F)F)CC3)c2o1>>COc1cc(N2CCN(CC(F)(F)F)CC2)c2oc(C(=O)O)cc(=O)c2c1 -US20150252044A1,3,CC(C)(C)CNC(=O)c1ccc2cncc(Br)c2n1.OB(O)c1ccccc1F>>CC(C)(C)CNC(=O)c1ccc2cncc(-c3ccccc3F)c2n1 -US06930104B2,1,COc1ccc(C(=O)N2c3ccccc3[C@H](O)C[C@@H]2C)cc1OC.c1ccc(CN2CCC3(CC2)CNc2ccccc23)cc1>>COc1ccc(C(=O)N2c3ccccc3C(N3CC4(CCN(Cc5ccccc5)CC4)c4ccccc43)CC2C)cc1OC -US20070185089A1,2,Cc1nc(C(=O)O)c(-c2ccccc2)s1.c1cc2c(cc1N1CCNCC1)CCN(C1CCC1)CC2>>Cc1nc(C(=O)N2CCN(c3ccc4c(c3)CCN(C3CCC3)CC4)CC2)c(-c2ccccc2)s1 -US20150045367A1,2,COC(=O)/C=C/c1ccccc1Oc1ccc(Cl)cc1.NO>>O=C(/C=C/c1ccccc1Oc1ccc(Cl)cc1)NO -US05017713,1,CC(=O)Nc1ccc(Br)c2c1C(=O)c1cccc(Cl)c1C2=O.CI>>CC(=O)N(C)c1ccc(Br)c2c1C(=O)c1cccc(Cl)c1C2=O -US07153815B2,2,CC(=NNc1ccc(C(F)(F)F)cc1)C(=O)O.NCc1ccc(Cl)nc1>>CC(=NNc1ccc(C(F)(F)F)cc1)C(=O)NCc1ccc(Cl)nc1 -US20110086860A1,3,COc1cc(C=O)ccc1F.C[Mg+]>>COc1cc(C(C)O)ccc1F -US20080058383A1,1,Cc1cc(F)ccc1[N+](=O)[O-].NC1(CO)CCCC1>>Cc1cc(NC2(CO)CCCC2)ccc1[N+](=O)[O-] -US05330998,2,Cc1oc(-c2ccccc2)nc1CC(=O)O.Nc1ccc(CC2SC(=O)NC2=O)cc1>>Cc1oc(-c2ccccc2)nc1CC(=O)Nc1ccc(CC2SC(=O)NC2=O)cc1 -US20080255149A1,7,C1=C(c2cccc(-c3ccccc3)c2)CCNC1>>c1ccc(-c2cccc(C3CCNCC3)c2)cc1 -US20070270437A1,1,CN1CCNCC1.COC(=O)c1sc(-n2cnc3ccc(C=O)cc32)cc1O[C@H](C)c1ccccc1C(F)(F)F>>COC(=O)c1sc(-n2cnc3ccc(CN4CCN(C)CC4)cc32)cc1O[C@H](C)c1ccccc1C(F)(F)F -US06878704B2,6,COC(=O)c1cn(-c2cccc([N+](=O)[O-])c2)[nH]c1=O>>O=C(O)c1cn(-c2cccc([N+](=O)[O-])c2)[nH]c1=O -US20140336207A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(Cc1ccccc1)C1C[C@H]2CCNC[C@H]2C1>>CN(Cc1ccccc1)C1C[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2C1 -US20090030003A1,1,CC(C)n1ncc2c(=O)[nH]c([C@@H]3CNC[C@H]3C)nc21.COc1ccc(C=O)cn1>>COc1ccc(CN2C[C@@H](C)[C@H](c3nc4c(cnn4C(C)C)c(=O)[nH]3)C2)cn1 -US20130190295A1,4,CC(=O)c1ccc(F)cc1.C[S+](C)C>>CC1(c2ccc(F)cc2)CO1 -US07544835B2,1,CI.O=Cc1c[nH]c2ccc(OCc3ccccc3)cc12>>Cn1cc(C=O)c2cc(OCc3ccccc3)ccc21 -US08466289B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCC1COC1>>Cc1ccc(S(=O)(=O)OCCC2COC2)cc1 -US20150165063A1,6,CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21>>Oc1cc2c(c3ccccc13)[C@H](CCl)CN2 -US06590118B1,3,CC(C)(C)OC(=O)Nc1ccccc1B(O)O.COC(=O)c1ccc(CBr)cc1C(=O)OC>>COC(=O)c1ccc(Cc2ccccc2NC(=O)OC(C)(C)C)cc1C(=O)OC -US04337258,6,CCOC(=O)C(=O)CC(=O)c1ccc(-c2ccc(S)cc2)cc1>>O=C(O)C(=O)CC(=O)c1ccc(-c2ccc(S)cc2)cc1 -US04870087,6,COc1ccc2c(CCCCN3CC=C(c4cccs4)CC3)c[nH]c2c1>>Oc1ccc2c(CCCCN3CC=C(c4cccs4)CC3)c[nH]c2c1 -US20100179168A1,6,COc1ccc(NC(=O)C(C)(CO)NC(=O)OC(C)(C)C)cc1NS(=O)(=O)c1ccc(-c2ccc(C)o2)c(F)c1>>COc1ccc(NC(=O)[C@@](C)(N)CO)cc1NS(=O)(=O)c1ccc(-c2ccc(C)o2)c(F)c1 -US20100004239A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CC2.O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1>>Cc1c(C=C2C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c32)[nH]c2c1C(=O)N(CCN1CCCCC1)CC2 -US20130267509A1,6,CC(C)(C)OC(=O)N1CCC(C(=O)Nc2nc(-c3ccco3)c(-c3ccncc3)s2)CC1>>O=C(Nc1nc(-c2ccco2)c(-c2ccncc2)s1)C1CCNCC1 -US05773388,7,Cc1ccccc1C(=O)c1cncnc1C(C)(C)C>>Cc1ccccc1C(O)c1cncnc1C(C)(C)C -US20070149547A1,2,COC(=O)c1nc(Br)cnc1SC.Nc1ccccn1>>CSc1ncc(Br)nc1C(=O)Nc1ccccn1 -US20090075980A1,2,CCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)N.O=C(Cl)c1cccnc1>>CCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)NC(=O)c1cccnc1 -US08604021B2,1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCN(c2cc(F)ccc2[N+](=O)[O-])CC1 -US20070135442A1,7,CCOC1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>CCOC1CCN(c2ccc(N)cc2)CC1 -US05519138,6,CCCCc1nc2ccc(N3CCCNC3=O)cc2n1Cc1ccc(OC(C(=O)OCC)c2ccccc2)cc1>>CCCCc1nc2ccc(N3CCCNC3=O)cc2n1Cc1ccc(OC(C(=O)O)c2ccccc2)cc1 -US20040087573A1,6,c1cc(N2CCC3(CC2)OCCO3)ccc1CN1CCOCC1>>O=C1CCN(c2ccc(CN3CCOCC3)cc2)CC1 -US20040023958A1,1,O=C1OC(CCc2ccc(OCc3ccccc3)cc2)(C2CCCC2)CC(O)=C1Cl.Oc1nc(S)nc2[nH]ccc12>>O=C1OC(CCc2ccc(OCc3ccccc3)cc2)(C2CCCC2)CC(O)=C1Sc1nc(O)c2cc[nH]c2n1 -US20090062273A1,6,COc1cc(-c2cncc3c2cnn3C)ccc1NC(=O)Nc1cccc(C(F)(F)F)c1>>Cn1ncc2c(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(O)c3)cncc21 -US05574037,1,CN.Clc1nc(Cl)nc(N2CCc3ccccc32)n1>>CNc1nc(Cl)nc(N2CCc3ccccc32)n1 -US07041687B2,1,CC(C)(C)OC(=O)NCCN.CC(C)(C)OC(=O)n1ncc2cc(NC(=O)C(OS(C)(=O)=O)c3cccc(Cl)c3)ccc21>>CC(C)(C)OC(=O)NCCNC(C(=O)Nc1ccc2c(cnn2C(=O)OC(C)(C)C)c1)c1cccc(Cl)c1 -US07482350B2,3,CCc1cccc(CC)c1B(O)O.COC(=O)c1c(C)nc(Cl)nc1OC>>CCc1cccc(CC)c1-c1nc(C)c(C(=O)OC)c(OC)n1 -US20020133011A1,7,O=C1CC(c2ccc(F)cc2)C(COc2ccc3c(c2)OCO3)CN1>>Fc1ccc(C2CCNCC2COc2ccc3c(c2)OCO3)cc1 -US20100240638A1,6,C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1NC(=O)CCCCCCCCC(=O)OC>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1NC(=O)CCCCCCCCC(=O)O -US20140024646A1,6,COC1COCCC1N[C@@H]1C[C@H]2CN(C(=O)OCc3ccccc3)C[C@@]2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1>>CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CNC[C@@]2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 -US20110201599A1,1,CN1CCNCC1.O=S(=O)(c1ccccc1)n1cc(I)c2c(Cl)ccnc21>>CN1CCN(c2ccnc3c2c(I)cn3S(=O)(=O)c2ccccc2)CC1 -US04499102,6,COC(=O)CC(C)C(=O)N1C(c2ccccc2O)SC[C@H]1C(=O)O>>CC(CC(=O)O)C(=O)N1C(c2ccccc2O)SC[C@H]1C(=O)O -US20070078155A1,1,Clc1nccc2cccnc12.Nc1ccc(F)cn1>>Fc1ccc(Nc2nccc3cccnc23)nc1 -US04461907,1,O=C(C=Cc1ccccc1)c1cc(Cl)ccc1O>>O=C1CC(c2ccccc2)Oc2ccc(Cl)cc21 -US20140128383A1,3,CCOC(=O)C(OC(C)(C)C)c1c(C)sc(C)c1B1OC(C)(C)C(C)(C)O1.Ic1ccccc1>>CCOC(=O)C(OC(C)(C)C)c1c(C)sc(C)c1-c1ccccc1 -US09096548B2,6,COC(=O)c1nc(Cl)c(N)nc1N>>Nc1nc(N)c(C(=O)O)nc1Cl -US06458814B1,2,CCOC(=O)CC(Cc1nc(C(=O)O)co1)c1ccccc1.NCCCNc1ccccn1>>CCOC(=O)CC(Cc1nc(C(=O)NCCCNc2ccccn2)co1)c1ccccc1 -US20060270706A1,6,COC(=O)Cn1cc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CCC2S)nn1>>O=C(O)Cn1cc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CCC2S)nn1 -US20120022069A1,6,CCOC(=O)/C(=C/C1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1)OC>>CO/C(=C\C1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1)C(=O)O -US20100158818A1,7,CC(=O)N1CCN(CC(C)(C)[N+](=O)[O-])CC1>>CC(=O)N1CCN(CC(C)(C)N)CC1 -US20110218177A1,1,CC(C)I.O=Cc1ccc(OCc2ccccc2)cc1O>>CC(C)Oc1cc(OCc2ccccc2)ccc1C=O -US05840732,1,CN1CCN(C=C2SC(=O)NC2=O)CC1.ClCCCCSc1cccc2nccn12>>CN1CCN(C=C2SC(=O)N(CCCCSc3cccc4nccn34)C2=O)CC1 -US20090233965A1,1,CI.CN1CCC(OC(=O)C(C)(c2ccc(C#N)cc2)C2CCCC2)CC1>>CC(C(=O)OC1CC[N+](C)(C)CC1)(c1ccc(C#N)cc1)C1CCCC1 -US07498325B2,1,CC(C)(C)OC(=O)N1CCC(N)CC1.CCOC(=O)Nc1cscc1C=O>>CCOC(=O)Nc1cscc1CNC1CCN(C(=O)OC(C)(C)C)CC1 -US20130165436A1,2,O=C(O)C1CCOCC1.O[C@@H]1CCNC1>>O=C(C1CCOCC1)N1CC[C@@H](O)C1 -US07531553B2,1,C=O.CC(=O)Nc1ccc(C(F)(F)F)c(OC[C@H]2CCCN2)c1>>CC(=O)Nc1ccc(C(F)(F)F)c(OC[C@H]2CCCN2C)c1 -US20130210795A1,6,CC(C)(C)OC(=O)NCCNC(=O)c1cccc(CSc2nc(N)c(C#N)c(-c3ccccc3)c2C#N)c1>>N#Cc1c(N)nc(SCc2cccc(C(=O)NCCN)c2)c(C#N)c1-c1ccccc1 -US20110190278A1,6,CC(C)N(C(=O)c1ccc2c(c1)N(CCNC(=O)OCc1ccccc1)C(=O)C2(C)C)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>CC(C)N(C(=O)c1ccc2c(c1)N(CCN)C(=O)C2(C)C)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20090227625A1,2,CC(COc1ccccc1)Oc1c(C(=O)O)ccc2ccccc12.COC(=O)C(C)(C)N>>COC(=O)C(C)(C)NC(=O)c1ccc2ccccc2c1OC(C)COc1ccccc1 -US07294637B2,2,CCOC(=O)[C@@H]1CCCNC1.O=C(Cl)C1(c2ccc(Cl)cc2)CCC1>>CCOC(=O)[C@@H]1CCCN(C(=O)C2(c3ccc(Cl)cc3)CCC2)C1 -US06403607B1,1,O=[N+]([O-])c1ccccc1F.Sc1ccc(Cl)cc1>>O=[N+]([O-])c1ccccc1Sc1ccc(Cl)cc1 -US04933355,3,Cc1ccccc1Nc1nc(C=O)cs1.O=C(O)CN1C(=O)CSC1=S>>Cc1ccccc1Nc1nc(C=C2SC(=S)N(CC(=O)O)C2=O)cs1 -US06936600B2,7,CCCC(=O)O[C@H](C)c1nccc(N2CCc3c(nc(C)nc3-c3ccccc3)C2)n1>>Cc1nc2c(c(-c3ccccc3)n1)CCN(c1ccnc([C@@H](C)O)n1)C2 -US05013749,7,CC(C)c1nc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1/C=C/[C@@H](O)CC(=O)CC(=O)OC(C)(C)C>>CC(C)c1nc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1/C=C/[C@@H](O)C[C@@H](O)CC(=O)OC(C)(C)C -US05366970,1,CI.c1cc2n(n1)CCCN2>>CN1CCCn2nccc21 -US08058276B2,6,COC(=O)c1coc2cc(O[Si](C(C)C)(C(C)C)C(C)C)ccc12>>COC(=O)c1coc2cc(O)ccc12 -US06274758B1,7,CCC/C(=C\S(=O)(=O)c1ccccc1)C(=O)O>>CCCC(CS(=O)(=O)c1ccccc1)C(=O)O -US06005109,3,Cc1ccc(C)cc1.O=C(Cl)CBr>>Cc1ccc(C)c(C(=O)CBr)c1 -US07262212B2,6,CC(C)(C)OC(=O)N1CCC(Nc2ccc(Cl)cc2)CC1>>Clc1ccc(NC2CCNCC2)cc1 -US03998808,1,N#C[S-].O=C(CCCl)N1CCCC1>>N#CSCCC(=O)N1CCCC1 -US05411973,7,CC(O)(C#Cc1ccc(S(=O)(=O)c2ccccc2)cc1)C(F)(F)F>>CC(O)(/C=C/c1ccc(S(=O)(=O)c2ccccc2)cc1)C(F)(F)F -US20050272765A1,4,CC(=O)O.CNc1c(N)ccc(-c2ccccc2Cl)c1C#N>>Cc1nc2ccc(-c3ccccc3Cl)c(C#N)c2n1C -US20150005275A1,6,CC(=O)Nc1sc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1C(N)=O>>NC(=O)c1cc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)sc1N -US04447425,7,CC(=O)O[C@@H]1CC[C@@H]2CC[C@H]3[C@@H]4C[C@H](N5CCCCC5)[C@H](O)[C@@]4(C)CC[C@@H]3[C@@]2(C)C1>>C[C@]12C[C@H](O)CC[C@@H]1CC[C@H]1[C@@H]3C[C@H](N4CCCCC4)[C@H](O)[C@@]3(C)CC[C@@H]12 -US08486967B2,6,Clc1cc(N2CCC3(CC2)OCCO3)ccn1>>O=C1CCN(c2ccnc(Cl)c2)CC1 -US20120165306A1,6,O=C(Nc1cc(-c2cncc(NCC3CCOCC3)n2)c(Cl)cn1)[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1F>>O=C(Nc1cc(-c2cncc(NCC3CCOCC3)n2)c(Cl)cn1)[C@H]1CNC[C@H]1F -US06140265,3,Cc1ccc(B(O)O)cc1.N#Cc1ccccc1Cl>>Cc1ccc(-c2ccccc2C#N)cc1 -US20010027196A1,1,CN.Nc1nc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c(-c2ccco2)n1>>CNc1nc(N)nc(-c2ccco2)c1[N+](=O)[O-] -US04933355,2,CCOC(=O)C(=O)c1csc(N)n1.COc1cc(N=C=O)cc(OC)c1OC>>CCOC(=O)C(=O)c1csc(NC(=O)Nc2cc(OC)c(OC)c(OC)c2)n1 -US08202881B2,6,CCOC(=O)c1cnc(Nc2nc3c(cc(C(=O)N(C4CC4)C4CC4)n3CC)c3c2ncn3C)s1>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3ncc(C(=O)O)s3)nc21 -US20050075394A1,1,Clc1cccc(Cl)c1CBr.OCCO>>OCCOCc1c(Cl)cccc1Cl -US20090171082A1,6,Cc1ccc(C(=O)N(CCCN2C(=O)c3ccccc3C2=O)C(c2nc3n(c(=O)c2Cc2ccccc2)CCCC3)C(C)C)cc1>>Cc1ccc(C(=O)N(CCCN)C(c2nc3n(c(=O)c2Cc2ccccc2)CCCC3)C(C)C)cc1 -US06559140B2,2,CC(=O)Cl.CC(=O)c1ccc(OCCCN2CCN(C(=O)[C@@H](C)N)CC2)cc1>>CC(=O)N[C@H](C)C(=O)N1CCN(CCCOc2ccc(C(C)=O)cc2)CC1 -US20090170901A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Fc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(Cl)cc2)CC1 -US07919621B2,1,Brc1ccc2c(ccc3ncnn32)c1.CCCCC(CC)COC(=O)CCS>>CCCCC(CC)COC(=O)CCSc1ccc2c(ccc3ncnn32)c1 -US20130109718A1,9,Cc1ccccc1[C@H](CC(=O)C1CCC(=O)N(C)C1)c1ccc(N2CCC(C(=O)[O-])CC2)cc1.NO>>Cc1ccccc1[C@H](C/C(=N\O)C1CCC(=O)N(C)C1)c1ccc(N2CCC(C(=O)[O-])CC2)cc1 -US20090238808A1,6,COc1cc2c(-c3ccc(Br)cc3F)nc(N)nc2cc1OCc1ccccc1>>COc1cc2c(-c3ccc(Br)cc3F)nc(N)nc2cc1O -US20140371199A1,2,C1COCCN1.O=C(O)c1ccc(-c2cn3c(I)cnc3cn2)cc1>>O=C(c1ccc(-c2cn3c(I)cnc3cn2)cc1)N1CCOCC1 -US20130190290A1,6,COc1ccc(Cn2cc(-c3cc4n(-c5cc(NC(=O)c6cc(N7CCOCC7)cc(S(F)(F)(F)(F)F)c6)ccc5C)ccn4n3)cn2)cc1>>Cc1ccc(NC(=O)c2cc(N3CCOCC3)cc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12 -US20140315881A1,6,CCOC(=O)CN1c2cc(CC(=O)NC(c3ccccc3)c3ccc(C)cc3C)ccc2NC1c1c(C)noc1C>>Cc1ccc(C(NC(=O)Cc2ccc3c(c2)N(CC(=O)O)C(c2c(C)noc2C)N3)c2ccccc2)c(C)c1 -US08093264B2,1,Ic1cccnc1.O=C1CCCN1>>O=C1CCCN1c1cccnc1 -US20130190307A1,7,CC(C)(C#N)c1ccc(Nc2c([N+](=O)[O-])nnc3ccc(Br)cc23)cc1>>CC(C)(C#N)c1ccc(Nc2c(N)nnc3ccc(Br)cc23)cc1 -US08034818B2,6,O=C1c2ccccc2C(=O)N1CCN1CCN(c2cccc3ccccc23)CC1>>NCCN1CCN(c2cccc3ccccc23)CC1 -US07981890B2,2,COC(=O)C(C)(C)NC(=O)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1>>CC1(C)NC(=O)N(c2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)C1=O -US20130178478A1,9,CCOC(=O)c1nnc(Cl)cc1Nc1cccc(-n2nccn2)n1.N>>NC(=O)c1nnc(Cl)cc1Nc1cccc(-n2nccn2)n1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCCC1.Oc1ccc2cc(F)cnc2c1>>COc1cc2c(Oc3ccc4cc(F)cnc4c3)ncnc2cc1OCCCN1CCCCC1 -US06281356B1,1,Cn1ccc2ccc(I)cc21.c1c[nH]cn1>>Cn1ccc2ccc(-n3ccnc3)cc21 -US08293902B2,2,CC(=O)Cl.COc1cc2ncnc(Oc3ccc4[nH]ccc4c3F)c2cc1OCC1CCNCC1>>COc1cc2ncnc(Oc3ccc4[nH]ccc4c3F)c2cc1OCC1CCN(C(C)=O)CC1 -US20080261941A1,1,CCOP(OCC)OCC.Cc1cccnc1Oc1cccc(CCl)c1>>CCOP(=O)(Cc1cccc(Oc2ncccc2C)c1)OCC -US20040121482A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H]1C=C[C@H](N)C1>>COC(=O)[C@@H]1C=C[C@H](NC(=O)OC(C)(C)C)C1 -US20120172351A1,6,COC(=O)C[C@@H]1COc2cc(NCc3cccc(-c4cc(C)sc4C)c3C)ccc21>>Cc1cc(-c2cccc(CNc3ccc4c(c3)OC[C@H]4CC(=O)O)c2C)c(C)s1 -US20110275638A1,2,CC(C)(C)OC(=O)N1CCN(CCOC(=O)N[C@@H](Cc2ccc(OC(C)(C)C)cc2)C(=O)O)CC1.CNCc1ccccc1>>CN(Cc1ccccc1)C(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OCCN1CCN(C(=O)OC(C)(C)C)CC1 -US05639768,6,CCOC(=O)C(C)(C)Oc1cc(OCCCCCOc2ccc(C=NN)cc2)ccc1C(=O)N(C(C)C)C(C)C>>CC(C)N(C(=O)c1ccc(OCCCCCOc2ccc(C=NN)cc2)cc1OC(C)(C)C(=O)O)C(C)C -US20150094297A1,2,CNCC#N.COc1cc(OCc2csc(C3(O)CCC(C(=O)O)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2csc(C3(O)CCC(C(=O)N(C)CC#N)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US20030176454A1,1,Cc1ncc(-c2cccc(N)c2)n1C.Clc1nccc2c(-c3ccsc3)cccc12>>Cc1ncc(-c2cccc(Nc3nccc4c(-c5ccsc5)cccc34)c2)n1C -US05371086,1,C1CCNC1.O=[N+]([O-])c1cnccc1Cl>>O=[N+]([O-])c1cnccc1N1CCCC1 -US08835428B2,1,COC(=O)C(NC(=O)c1cc(-c2ccc(O)cc2)no1)C(C)C.Fc1ccc2nc(Cl)sc2c1>>COC(=O)C(NC(=O)c1cc(-c2ccc(Oc3nc4ccc(F)cc4s3)cc2)no1)C(C)C -US07632829B2,6,COC(=O)/C=C/c1cnc(Cl)c(Cl)c1>>O=C(O)/C=C/c1cnc(Cl)c(Cl)c1 -US20060211739A1,1,BrCc1cccnc1.FC(F)(F)c1ccccc1-c1nnn[nH]1>>FC(F)(F)c1ccccc1-c1nnnn1Cc1cccnc1 -US20150191419A1,1,CC(C)(C)OC(=O)NCC(=O)CCC(=O)[O-].O=C(CCCBr)OCc1ccccc1>>CC(C)(C)OC(=O)NCC(=O)CCC(=O)OCCCC(=O)OCc1ccccc1 -US20070293515A1,1,CC(C)(C)OC(=O)N[C@H]1CC[C@H](C(=O)O/N=C(\N)C(F)(F)c2ccccc2)C1>>CC(C)(C)OC(=O)N[C@H]1CC[C@H](c2nc(C(F)(F)c3ccccc3)no2)C1 -US20050261327A1,2,CS(=O)(=O)Cl.OCC1CCC2(CC1)OC=Cc1ccccc12>>CS(=O)(=O)OCC1CCC2(CC1)OC=Cc1ccccc12 -US20060281803A1,2,Cn1nc(-c2cccs2)cc1N.O=C(Cl)c1ccc(C(F)(F)F)cc1>>Cn1nc(-c2cccs2)cc1NC(=O)c1ccc(C(F)(F)F)cc1 -US07960369B2,1,CCc1cccc(CC)c1-c1cccc(CO)c1.COC(=O)CCc1ccc(O)cc1>>CCc1cccc(CC)c1-c1cccc(COc2ccc(CCC(=O)OC)cc2)c1 -US20060063784A1,1,BrCC1CCC1.O=C(c1cccs1)c1cnn2c(-c3cccc(-c4nnn[nH]4)c3)ccnc12>>O=C(c1cccs1)c1cnn2c(-c3cccc(-c4nnnn4CC4CCC4)c3)ccnc12 -US20110301123A1,1,CSCC(C)N.Clc1cc(-c2ccnc(Cl)n2)ccn1>>CSCC(C)Nc1nccc(-c2ccnc(Cl)c2)n1 -US05773628,2,CC(=O)Cl.Oc1cccc(C2(OCC(F)(F)F)OOC23C2CC4CC(C2)CC3C4)c1>>CC(=O)Oc1cccc(C2(OCC(F)(F)F)OOC23C2CC4CC(C2)CC3C4)c1 -US07544690B2,9,CN(C)c1nc(N[C@@H]2CC[C@H](NCc3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12.N>>CN(C)c1nc(N[C@@H]2CC[C@H](NCc3ccc(N)cc3OC(F)(F)F)CC2)nc2ccccc12 -US20080200467A1,2,Nc1cccc(OCc2ccccc2)c1.O=C(O)C(O)CC1CCCCC1>>O=C(Nc1cccc(OCc2ccccc2)c1)C(O)CC1CCCCC1 -US20070275968A1,3,Cc1cccc(-c2[nH]c(C(C)C)nc2-c2cccc(Br)c2)n1.O=[N+]([O-])c1ccc(B(O)O)cc1>>Cc1cccc(-c2[nH]c(C(C)C)nc2-c2cccc(-c3ccc([N+](=O)[O-])cc3)c2)n1 -US20030187051A1,2,C1=CCNC1.O=C(N[C@@H](Cc1ccccc1)[C@@H](O)C(=O)O)c1cc2cc(Cl)ccc2[nH]1>>O=C(N[C@@H](Cc1ccccc1)[C@@H](O)C(=O)N1CC=CC1)c1cc2cc(Cl)ccc2[nH]1 -US05484942,2,CN(C)c1ccccc1CC(=O)O.c1ccc(C2(c3ccccc3)CCSC3CNCC32)cc1>>CN(C)c1ccccc1CC(=O)N1CC2SCCC(c3ccccc3)(c3ccccc3)C2C1 -US20120121540A1,6,CCOC(=O)c1cn2cc(Br)cc(C(F)(F)F)c2n1>>O=C(O)c1cn2cc(Br)cc(C(F)(F)F)c2n1 -US06552069B1,6,CCOC(=O)C(CCCCCCCCC1c2ccc(O)cc2OCC1(C)c1ccc(O)cc1)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CC1(c2ccc(O)cc2)COc2cc(O)ccc2C1CCCCCCCCC(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O -US07196199B2,6,COCOc1cccc2oc(-c3nnc(SC)o3)cc12>>CSc1nnc(-c2cc3c(O)cccc3o2)o1 -US05399578,6,CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@H]1CCCC[C@H]1C(=O)OCC>>CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@@H]1CCCC[C@@H]1C(=O)O -US20060223801A1,6,CCOC(=O)c1[nH]c(C)c(Cl)c1C>>Cc1[nH]c(C(=O)O)c(C)c1Cl -US06362177B1,6,CC(C)(C)OC(=O)NC1CCN(Cc2ccc(Cl)cc2)C1>>NC1CCN(Cc2ccc(Cl)cc2)C1 -US04518597,1,Cc1cc(OCCCCCl)cc2c1NC(=O)OC2(C)C.Sc1ccccn1>>Cc1cc(OCCCCSc2ccccn2)cc2c1NC(=O)OC2(C)C -US05620979,7,Nc1ccc(F)cc1[N+](=O)[O-]>>Nc1ccc(F)cc1N -US20100261710A1,2,COC(=O)CCCCCCN.O=C(O)C(=O)c1cn2c3c(cccc13)CCC2>>COC(=O)CCCCCCNC(=O)C(=O)c1cn2c3c(cccc13)CCC2 -US20080188528A1,1,CC(=N)O.NCCC[C@H](NC(=O)c1ccc(C(c2ccccc2Cl)c2ccccc2Cl)s1)C(=O)O>>CC(=N)NCCC[C@H](NC(=O)c1ccc(C(c2ccccc2Cl)c2ccccc2Cl)s1)C(=O)O -US20150038438A1,2,O=C(Cl)OCc1ccccc1.O=C1CCCNc2cc(Cl)ccc21>>O=C1CCCN(C(=O)OCc2ccccc2)c2cc(Cl)ccc21 -US20130165436A1,6,COc1ncc(N2CCOc3ccc(O[Si](C)(C)C(C)(C)C)cc32)cc1C#N>>COc1ncc(N2CCOc3ccc(O)cc32)cc1C#N -US20100234351A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(N)cc2Cl)CC1.COC(=O)CCCCN(Cc1ccc(OC)cc1)c1ncnc(Cl)c1C=O>>COC(=O)CCCCN(Cc1ccc(OC)cc1)c1ncnc(Nc2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)c(Cl)c2)c1C=O -US08431695B2,3,CC1(C)OB(c2ccc3cn(Cc4ccccc4)nc3c2)OC1(C)C.Nc1ncnn2c(CCO)cc(Br)c12>>Nc1ncnn2c(CCO)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12 -US06172227B2,1,NC1(Cl)N=C(Cc2ccccc2)C([N+](=O)[O-])=CN1.c1nnn[nH]1>>NC1(n2cnnn2)N=C(Cc2ccccc2)C([N+](=O)[O-])=CN1 -US07037927B2,1,CC(C)(C)c1ccc(NC(=O)c2ccc(Cl)nc2)cc1.c1cn[nH]c1>>CC(C)(C)c1ccc(NC(=O)c2ccc(-n3cccn3)nc2)cc1 -US20100137397A1,2,COC(=O)C(CC1CC1)[C@@H]1c2ccccc2C[C@H]1N.O=C(O)c1cc2sc(Cl)c(Cl)c2[nH]1>>COC(=O)C(CC1CC1)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1 -US07964591B2,2,CC1CCCC(C(=O)O)C1.O=C(NCCC1CC1)c1ccc(N2CCNCC2)nn1>>CC1CCCC(C(=O)N2CCN(c3ccc(C(=O)NCCC4CC4)nn3)CC2)C1 -US20150284370A1,3,CCN(c1cc(B2OC(C)(C)C(C)(C)O2)cc(C(=O)OC)c1C)C1CCOCC1.CN1CCC(Oc2ccc(Br)cn2)CC1>>CCN(c1cc(-c2ccc(OC3CCN(C)CC3)nc2)cc(C(=O)OC)c1C)C1CCOCC1 -US08071605B2,1,C=CCO[C@H]1CNCC[C@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl.COC(=O)c1sc(Cl)nc1-c1ncnn1C>>C=CCO[C@H]1CN(c2nc(-c3ncnn3C)c(C(=O)OC)s2)CC[C@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl -US20060100230A1,7,Cc1cc(Br)cc2c(C(C)C)c[nH]c12>>Cc1cc(Br)cc2c1NCC2C(C)C -US04710573,4,CC(=O)N1CCC(C(=O)c2ccc(F)cc2F)CC1.CNN>>CC(=O)N1CCC(c2nn(C)c3cc(F)ccc23)CC1 -US04942168,1,CC(O)CNc1c(Br)cnc2ccccc12>>CC1CNc2c(cnc3ccccc23)O1 -US20110086834A1,1,Brc1cccc(Nc2ccncn2)n1.ClCCN1CCOCC1>>Brc1cccc(N(CCN2CCOCC2)c2ccncn2)n1 -US07232827B2,1,CC1(C)CNc2nc(-c3ccncn3)cc(=O)n2C1.CS(=O)(=O)OCC1Cc2nccnc2C1>>CC1(C)CN(CC2Cc3nccnc3C2)c2nc(-c3ccncn3)cc(=O)n2C1 -US20080119536A1,1,CCC(=O)OCCl.Cc1cccc(C(C)c2ncc[nH]2)c1C>>CCC(=O)OCn1ccnc1C(C)c1cccc(C)c1C -US04528024,2,COCCS(=O)(=O)c1ccccc1S(=O)(=O)N=C=O.COc1cc(OC)nc(N)n1>>COCCS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1 -US07534894B2,6,CCCc1c(C(=O)NCc2ccc(-c3ccc(OCC(=O)OC)cc3)cc2)cnn1-c1ccccc1>>CCCc1c(C(=O)NCc2ccc(-c3ccc(OCC(=O)O)cc3)cc2)cnn1-c1ccccc1 -US20120283245A1,1,ClCCCBr.NC(=O)c1ccc(O)cc1>>NC(=O)c1ccc(OCCCCl)cc1 -US07148226B2,1,Cc1cc(C)n2nc(S)nc2n1.Cc1noc(C)c1-c1ccc(CCC2(C3CCCC3)CC(O)=C(Cl)C(=O)O2)cc1>>Cc1cc(C)n2nc(SC3=C(O)CC(CCc4ccc(-c5c(C)noc5C)cc4)(C4CCCC4)OC3=O)nc2n1 -US06599905B2,1,CNC.Nc1nc(Cl)cnc1-c1cccc(Cl)c1Cl>>CN(C)c1cnc(-c2cccc(Cl)c2Cl)c(N)n1 -US20150232492A1,7,CCOC(=O)C(C)(c1ccc2c(C(F)(F)F)c(O[C@@H]3CC[C@@H](C(C)(C)C)CC3)ccc2n1)[N+](=O)[O-]>>CCOC(=O)C(C)(N)c1ccc2c(C(F)(F)F)c(O[C@@H]3CC[C@@H](C(C)(C)C)CC3)ccc2n1 -US20150210698A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCNCC1>>CC(C)(C)OC(=O)N1CCC(N2CCC(n3cc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 -US05102877,2,O=C(Cl)OCc1ccc([N+](=O)[O-])cc1.O=C(O)[C@@H]1CSCN1>>O=C(O)[C@@H]1CSCN1C(=O)OCc1ccc([N+](=O)[O-])cc1 -US20150065482A1,9,COC(=O)c1nn(-c2cc(C#C[C@]3(O)CCN(C)C3=O)cc(C(C)O)c2)c2ncccc12.N>>CC(O)c1cc(C#C[C@]2(O)CCN(C)C2=O)cc(-n2nc(C(N)=O)c3cccnc32)c1 -US20150266848A1,6,CC(=O)O[C@H](COCc1ccccc1)[C@@H](O)c1ccccc1Cl>>O[C@H](COCc1ccccc1)[C@@H](O)c1ccccc1Cl -US20100035953A1,6,COC(=O)C(C)(C)Oc1cc(Cl)c(OCc2cc(-c3ccc(OC(F)(F)F)cc3)nn2C)cc1Cl>>Cn1nc(-c2ccc(OC(F)(F)F)cc2)cc1COc1cc(Cl)c(OC(C)(C)C(=O)O)cc1Cl -US20060084654A1,1,COc1cccc(CBr)c1.Nc1nccn2c(C3CCC3)nc(-c3cccc(O)c3)c12>>COc1cccc(COc2cccc(-c3nc(C4CCC4)n4ccnc(N)c34)c2)c1 -US20050075326A1,1,O=C(CCCl)c1ccccc1.O=C1N(Cc2ccc(Br)cc2)CCC12CCNCC2>>O=C(CCN1CCC2(CC1)CCN(Cc1ccc(Br)cc1)C2=O)c1ccccc1 -US07705004B2,2,CS(=O)(=O)Cl.c1cc2c(Nc3ccc4cn[nH]c4c3)nc(Nc3ccc(N4CCNCC4)cc3)nc2[nH]1>>CS(=O)(=O)N1CCN(c2ccc(Nc3nc(Nc4ccc5cn[nH]c5c4)c4cc[nH]c4n3)cc2)CC1 -US20140128385A1,2,CC(C)(C)OC(=O)NC1=NC(C)(c2cc(N)ccc2F)COC1(CF)CF.Cc1cc(C#N)cnc1C(=O)O>>Cc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(C)COC(CF)(CF)C(NC(=O)OC(C)(C)C)=N2)c1 -US20080227783A1,1,Clc1ccccn1.Nc1nccs1>>c1ccc(Nc2nccs2)nc1 -US04723006,1,C[O-].Nc1nc(Cl)cc(C=C(Cl)Cl)n1>>COc1cc(C=C(Cl)Cl)nc(N)n1 -US20110306597A1,9,N.O=C1C(Br)CCN1Cc1ccc(Cl)cc1>>NC1CCN(Cc2ccc(Cl)cc2)C1=O -US20130225524A1,3,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(Cl)ccc23)c1.OB(O)c1cc(F)ccc1F>>CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4cc(F)ccc4F)ccc23)c1 -US20100034827A1,9,COC(OC)c1cc(C)cc(CBr)c1.[C-]#N>>COC(OC)c1cc(C)cc(CC#N)c1 -US08829040B2,6,CCOC(=O)c1ccc(-n2cc(C#N)c3c(OCc4ccccc4)cccc32)cc1>>N#Cc1cn(-c2ccc(C(=O)O)cc2)c2cccc(OCc3ccccc3)c12 -US20060211678A1,4,NC(N)=S.O=C(CBr)c1cccc([N+](=O)[O-])c1>>Nc1nc(-c2cccc([N+](=O)[O-])c2)cs1 -US20110112158A1,3,COc1cc(F)c(F)cc1B(O)O.Oc1ccc(I)cc1>>COc1cc(F)c(F)cc1-c1ccc(O)cc1 -US08314109B2,3,C[Sn](C)(C)c1ccc2nc(C(=O)Nc3ccccc3)cn2c1.OCc1cncc(Br)c1>>O=C(Nc1ccccc1)c1cn2cc(-c3cncc(CO)c3)ccc2n1 -US04597902,2,CC(C)NCCSc1ccc(Cl)cc1.O=C(Cl)Oc1ccccc1>>CC(C)N(CCSc1ccc(Cl)cc1)C(=O)Oc1ccccc1 -US20030162795A1,1,NCc1cccs1.O=Cc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1>>c1csc(CNCc2ccc(-c3cc4ncnc(Nc5ccc6[nH]ccc6c5)c4s3)cc2)c1 -US04694017,2,NC(CC1C(=O)Nc2ccccc21)C(=O)O.O=C(O)c1ccc(Cl)cc1>>O=C(NC(CC1C(=O)Nc2ccccc21)C(=O)O)c1ccc(Cl)cc1 -US08314109B2,5,O=Cc1ccc2nc(C(=O)Nc3ccccc3)cn2c1.OCCO>>O=C(Nc1ccccc1)c1cn2cc(C3OCCO3)ccc2n1 -US04264599,1,COc1ncccc1O.ClCC1CO1>>COc1ncccc1OCC1CO1 -US20100113510A1,1,C[C@](C(=O)O[C@H]1CN2CCC1CC2)(c1ccccc1)N1CCCCC1.O=C(CBr)Nc1ccon1>>C[C@](C(=O)O[C@H]1C[N+]2(CC(=O)Nc3ccon3)CCC1CC2)(c1ccccc1)N1CCCCC1 -US20050171131A1,1,NCc1ccccc1.Nc1nc(N)c(Br)c(Cl)n1>>Nc1nc(N)c(Br)c(NCc2ccccc2)n1 -US20150191450A1,9,Brc1cccc2cnccc12.[C-]#N>>N#Cc1cccc2cnccc12 -US20050119305A1,2,NN.O=C(O)CCCCC(O)c1ccc(-c2ccc(Cl)cc2)cc1>>NNC(=O)CCCCC(O)c1ccc(-c2ccc(Cl)cc2)cc1 -US06812226B2,1,COC(=O)c1ccccc1C(=O)c1ccc(Cl)c([N+](=O)[O-])c1.O=C1OCc2ccc(Cl)cc2N1C1CCNCC1>>COC(=O)c1ccccc1C(=O)c1ccc(N2CCC(N3C(=O)OCc4ccc(Cl)cc43)CC2)c([N+](=O)[O-])c1 -US06204293B1,1,COC(=O)c1ccc(CBr)cc1-c1ccccc1C.OCc1cccs1>>COC(=O)c1ccc(COCc2cccs2)cc1-c1ccccc1C -US20070010537A1,6,CCOC(=O)CCc1cccc2[nH]c(=O)n(-c3cccc(S(=O)(=O)N4CCCc5ccccc54)c3)c(=O)c12>>O=C(O)CCc1cccc2[nH]c(=O)n(-c3cccc(S(=O)(=O)N4CCCc5ccccc54)c3)c(=O)c12 -US20070219210A1,2,CCNC.Cc1ccc(-n2nc(C(=O)O)cc2-c2ccc(OCc3ccccc3)cn2)cn1>>CCN(C)C(=O)c1cc(-c2ccc(OCc3ccccc3)cn2)n(-c2ccc(C)nc2)n1 -US04964896,6,COC(=O)c1c(-c2ccccc2)n(C)c(-c2ccccc2)cc1=O>>Cn1c(-c2ccccc2)cc(=O)c(C(=O)O)c1-c1ccccc1 -US20070219210A1,4,CCOC(=O)C(=O)CC(=O)c1ccc(C)cn1.NNc1cccnc1>>CCOC(=O)c1cc(-c2ccc(C)cn2)n(-c2cccnc2)n1 -US20130158075A1,6,CC(C)(C)OC(=O)N1CCC(c2ncc(-c3ccc([N+](=O)[O-])cc3)s2)CC1>>O=[N+]([O-])c1ccc(-c2cnc(C3CCNCC3)s2)cc1 -US07319104B2,1,CCc1cnc(Cl)nc1.COc1ccc(CCN)cc1Br>>CCc1cnc(NCCc2ccc(OC)c(Br)c2)nc1 -US06172064B2,7,C[C@H]1[C@@H](C/C=C/c2ccc(Cl)cc2)C(=O)N1OC1CCCCO1>>C[C@H]1[C@@H](CCCc2ccc(Cl)cc2)C(=O)N1OC1CCCCO1 -US20040259912A1,7,COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccccc1)c1c(F)cccc1F>>COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1c(F)cccc1F -US05591762,6,CCCc1nc2c(C)cc(-c3cn(CC(F)(F)F)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCc1nc2c(C)cc(-c3cn(CC(F)(F)F)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US08629147B2,2,CNC.COc1ncccc1-c1ccc(O)c(-c2nc3ccc(C(=O)O)cc3[nH]2)c1>>COc1ncccc1-c1ccc(O)c(-c2nc3ccc(C(=O)N(C)C)cc3[nH]2)c1 -US20060287309A1,1,Cc1ccnc(N2CCNCC2)n1.O=CCCCOc1ccc2c(n1)NC(=O)CC2>>Cc1ccnc(N2CCN(CCCCOc3ccc4c(n3)NC(=O)CC4)CC2)n1 -US08524657B2,1,C=CCBr.COC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O>>C=CCOc1ccc(C[C@@H](NC(C)=O)C(=O)OC)cc1 -US08063046B2,2,COc1ccc(C(=O)O)cc1/C=C/c1ccc(OC(F)(F)F)cc1.NC(CO)CO>>COc1ccc(C(=O)NC(CO)CO)cc1/C=C/c1ccc(OC(F)(F)F)cc1 -US20050096380A1,8,CCOc1c(/C(CC)=C(/F)CO)cc2c(c1Br)C(C)(C)CC=C2C(C)C>>CCOc1c(/C(CC)=C(/F)C=O)cc2c(c1Br)C(C)(C)CC=C2C(C)C -US20060089367A1,2,C=CCN.O=C(O)c1ccc2c(c1)nc(COc1ccccc1)n2Cc1ccc(OC(F)(F)F)cc1>>C=CCNC(=O)c1ccc2c(c1)nc(COc1ccccc1)n2Cc1ccc(OC(F)(F)F)cc1 -US05418239,6,COc1cc(NC(=O)Nc2c(-c3ccccc3C)c3cc4c(cc3oc2=O)CCC4)cc(OC)c1OC(C)=O>>COc1cc(NC(=O)Nc2c(-c3ccccc3C)c3cc4c(cc3oc2=O)CCC4)cc(OC)c1O -US20120050945A1,1,C1CCCNCC1.CCCCBr>>CCCCN1CCCCCC1 -US20040127536A1,7,O=C(Nc1ccc2[nH]nc(-c3ccc(F)cc3)c2c1)c1ccncc1>>Fc1ccc(-c2n[nH]c3ccc(NCc4ccncc4)cc23)cc1 -US20100160386A1,6,CCOC(=O)c1cnc(-c2cc(F)cc(F)c2)cc1Oc1ccccc1Cl>>O=C(O)c1cnc(-c2cc(F)cc(F)c2)cc1Oc1ccccc1Cl -US20030171396A1,7,Nc1nc(Br)ccc1[N+](=O)[O-]>>Nc1ccc(Br)nc1N -US20100099729A1,1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=[N+]([O-])OCCCCBr>>CC(C)(C)OC(=O)NC(Cc1ccc(O)cc1)C(=O)OCCCCO[N+](=O)[O-] -US04996216,1,ClCn1cnc(Cl)c1Cl.Oc1ccc(Oc2cccc(Cl)n2)cc1>>Clc1cccc(Oc2ccc(OCn3cnc(Cl)c3Cl)cc2)n1 -US06979686B1,1,Fc1ccc(-c2n[nH]cc2-c2ccnc(Cl)n2)cc1.Nc1ccccc1F>>Fc1ccc(-c2n[nH]cc2-c2ccnc(Nc3ccccc3F)n2)cc1 -US06090947,1,O=C(CBr)c1ccccc1.O=C(O)c1ccc(CBr)cc1>>O=C(COC(=O)c1ccc(CBr)cc1)c1ccccc1 -US06403578B1,1,CC(C)(C)OC(=O)c1ccc(CBr)c([N+](=O)[O-])c1.COC(=O)/C=C/CNCCc1ccccc1>>COC(=O)/C=C/CN(CCc1ccccc1)Cc1ccc(C(=O)OC(C)(C)C)cc1[N+](=O)[O-] -US08329716B2,3,CC(=O)Nc1ccc(Oc2ccnc3c2c(Br)cn3S(=O)(=O)c2ccc(C)cc2)c(F)c1.OB(O)C1CC1>>CC(=O)Nc1ccc(Oc2ccnc3c2c(C2CC2)cn3S(=O)(=O)c2ccc(C)cc2)c(F)c1 -US20140066432A1,6,CCCN(CC(N)=O)C(=O)C1=Cc2cc(-c3ccc(NC(=O)OCC)cc3Cl)ccc2N=C(NC(=O)OC(C)(C)C)C1>>CCCN(CC(N)=O)C(=O)C1=Cc2cc(-c3ccc(NC(=O)OCC)cc3Cl)ccc2N=C(N)C1 -US03971819,6,CCCCNS(=O)(=O)c1cc(C(=O)OCC)cc(NCc2ccccc2)c1Oc1ccccc1>>CCCCNS(=O)(=O)c1cc(C(=O)O)cc(NCc2ccccc2)c1Oc1ccccc1 -US20110046127A1,3,CCOC(=O)CP(=O)(OCC)OCC.COC(C=O)OC>>CCOC(=O)/C=C/C(OC)OC -US04160862,2,Cc1[nH]c2ccc(OC(C)(C)C)cc2c1CCN1CCCCC1CC1CCCCC1.O=C(Cl)c1ccccc1>>Cc1c(CCN2CCCCC2CC2CCCCC2)c2cc(OC(C)(C)C)ccc2n1C(=O)c1ccccc1 -US20130267493A1,6,COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(C4CCOCC4)cc3)cc12>>O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(C4CCOCC4)cc3)cc12 -US20060229336A1,2,Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCNCC1.O=C(Cl)c1ccccc1>>Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccccc2)CC1 -US20120115867A1,1,CN1CCNCC1.N#Cc1ccc(CBr)cc1>>CN1CCN(Cc2ccc(C#N)cc2)CC1 -US07745496B2,1,COc1cc(/C=C/C(=O)[O-])ccc1O.O=[N+]([O-])OCCCCBr>>COc1cc(/C=C/C(=O)OCCCCO[N+](=O)[O-])ccc1O -US20080200448A1,2,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCC1=O.CN(c1ccccc1)S(N)(=O)=O>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)N(C)c3ccccc3)CC2)nc1CN1CCCC1=O -US20120142665A1,6,CC(C)(C)OC(=O)Nc1ccn2nc(N3CCCC3)nc2c1>>Nc1ccn2nc(N3CCCC3)nc2c1 -US20130303507A1,1,FC(F)(F)CCBr.N#CC1(COc2cncc(-c3cc(N[C@@H]4CC[C@@H](N)CC4)ncc3Cl)n2)CCOCC1>>N#CC1(COc2cncc(-c3cc(N[C@@H]4CC[C@@H](NCCC(F)(F)F)CC4)ncc3Cl)n2)CCOCC1 -US05401868,2,CCC(=O)OCOC(=O)Cl.O=[N+]([O-])c1ccc(O)cc1>>CCC(=O)OCOC(=O)Oc1ccc([N+](=O)[O-])cc1 -US20060287309A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=S(=O)(Oc1cccc2cc(F)ccc12)C(F)(F)F>>CC(C)(C)OC(=O)N1CCN(c2cccc3cc(F)ccc23)CC1 -US08058245B2,1,Cc1ccc(CCl)cc1.c1ccc(COC[C@H]2O[C@@H](c3ccc4cc[nH]c4c3)[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1>>Cc1ccc(Cn2ccc3ccc([C@@H]4O[C@H](COCc5ccccc5)[C@@H](OCc5ccccc5)[C@H](OCc5ccccc5)[C@H]4OCc4ccccc4)cc32)cc1 -US20120101100A1,2,CCNC(=O)Nc1cc(CO)c(-c2cncc(-c3n[nH]c(=O)o3)c2)cn1.CS(=O)(=O)Cl>>CCNC(=O)Nc1cc(COS(C)(=O)=O)c(-c2cncc(-c3n[nH]c(=O)o3)c2)cn1 -US20150191461A1,6,Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnn(CCO[Si](C)(C)C(C)(C)C)c2)c1>>Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnn(CCO)c2)c1 -US06924292B2,3,CN(C)C=O.COc1cccc2c1OCC2>>COc1cc(C=O)cc2c1OCC2 -US04853384,2,CN=C=O.Fc1c(F)c(F)c(OC2(c3ccccc3)CCNCC2)c(F)c1F>>CNC(=O)N1CCC(Oc2c(F)c(F)c(F)c(F)c2F)(c2ccccc2)CC1 -US04177290,6,CCOC(=O)CC(=O)N(c1ccccc1)c1ccccc1>>O=C(O)CC(=O)N(c1ccccc1)c1ccccc1 -US05948793,6,CC(C)(C)OC(=O)N1CC[C@H]1COc1ccc(Cl)nn1>>Clc1ccc(OC[C@@H]2CCN2)nn1 -US08003649B2,1,CSc1nnc2ccc(Cl)nn12.c1ccc(CN2CCCNCC2)cc1>>CSc1nnc2ccc(N3CCCN(Cc4ccccc4)CC3)nn12 -US20040014802A1,2,CCCC(=O)Cl.Nc1n[nH]c2c(F)c(Br)c(F)c(F)c12>>CCCC(=O)Nc1n[nH]c2c(F)c(Br)c(F)c(F)c12 -US20090093473A1,7,CCOC(=O)c1cc2c(nc(C)n2C)c2c1C(=O)CC1(Cc3ccccc3C1)N2>>CCOC(=O)c1cc2c(nc(C)n2C)c2c1CCC1(Cc3ccccc3C1)N2 -US20150018309A1,2,Cc1nnc2sc(C(=O)O)c(N)c2c1C.NCc1ccc(OCF)cc1>>Cc1nnc2sc(C(=O)NCc3ccc(OCF)cc3)c(N)c2c1C -US20120288492A1,2,CCOC(=O)c1nc(-c2ccc(N)cc2)nc(N2CCOCC2)c1OCC.O=C=Nc1ccccc1>>CCOC(=O)c1nc(-c2ccc(NC(=O)Nc3ccccc3)cc2)nc(N2CCOCC2)c1OCC -US07368571B2,2,CCOC(=O)c1cc2ccn(Cc3ccc(F)cc3)c2cn1.NO>>O=C(NO)c1cc2ccn(Cc3ccc(F)cc3)c2cn1 -US20140018533A1,3,CCNC1=C(C(=O)OCC)C(=O)CO1.O=Cc1c[nH]c2ncccc12>>CCNC1=C(C(=O)OCC)C(=O)C(=Cc2c[nH]c3ncccc23)O1 -US20030187020A1,2,N#CC1(c2cccc(CNC(=O)OCc3ccccc3)c2)CCNCC1.O=C(O)c1cncc(CCc2ccccc2)c1>>N#CC1(c2cccc(CNC(=O)OCc3ccccc3)c2)CCN(C(=O)c2cncc(CCc3ccccc3)c2)CC1 -US20040082607A1,3,COC(=O)c1c(OS(=O)(=O)C(F)(F)F)c2cc(OCc3ccccc3)ccc2c(=O)n1CC(C)C.OB(O)c1ccc(Cl)cc1>>COC(=O)c1c(-c2ccc(Cl)cc2)c2cc(OCc3ccccc3)ccc2c(=O)n1CC(C)C -US09089569B2,1,Cn1ccc(COc2ccc3nc([C@H]4CCCC[C@H]4C(=O)O)n(Cc4ccc(Br)cc4)c3c2)n1.FC1(F)CNC1>>Cn1ccc(COc2ccc3nc([C@H]4CCCC[C@H]4C(=O)O)n(Cc4ccc(N5CC(F)(F)C5)cc4)c3c2)n1 -US20150232448A1,6,CC(=O)NCc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)c(CN)c2)CC1 -US20140249104A1,6,Cc1cc(Cl)cnc1C(=O)Nc1ccc(F)c([C@]2(C)C[C@@H](C(F)(F)F)OC(NC(=O)c3ccccc3)=N2)c1>>Cc1cc(Cl)cnc1C(=O)Nc1ccc(F)c(C2(C)CC(C(F)(F)F)OC(N)=N2)c1 -US20080312192A1,9,[N-]=[N+]=Nc1cc(Oc2ccc(NC(=O)Nc3cc(CN4CCC4)cc(C(F)(F)F)c3)cc2)ncn1>>Nc1cc(Oc2ccc(NC(=O)Nc3cc(CN4CCC4)cc(C(F)(F)F)c3)cc2)ncn1 -US07622479B2,6,COc1cccc(-c2nc3ncc(-c4ccccc4)cc3n2CC(=O)OC(C)(C)C)c1>>COc1cccc(-c2nc3ncc(-c4ccccc4)cc3n2CC(=O)O)c1 -US20050143452A1,9,[N-]=[N+]=NCC1Cc2cccc(-c3cccc(F)c3)c2O1>>NCC1Cc2cccc(-c3cccc(F)c3)c2O1 -US20110230495A1,2,CO.O=C(O)c1ncccc1Br>>COC(=O)c1ncccc1Br -US04613675,1,CCOP(C)(=O)C(C)OS(C)(=O)=O.O=[N+]([O-])c1cc(O)c(Cl)cc1Cl>>CCOP(C)(=O)C(C)Oc1cc([N+](=O)[O-])c(Cl)cc1Cl -US08436008B2,1,CC(C)(C)[Si](C)(C)OCCBr.CC1(C)OB(c2cnn(C3CCNCC3)c2)OC1(C)C>>CC1(C)OB(c2cnn(C3CCN(CCO[Si](C)(C)C(C)(C)C)CC3)c2)OC1(C)C -US08003785B2,1,CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21.COc1cc(C(=O)NC2CCN(CCCS(C)(=O)=O)CC2)ccc1N>>COc1cc(C(=O)NC2CCN(CCCS(C)(=O)=O)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US03997557,4,CC1CCC(=O)C(CC(=O)c2ccccc2)C1.CCN(CC)CCN>>CCN(CC)CCn1c(-c2ccccc2)cc2c1CCC(C)C2 -US20090062251A1,2,CNCCN(C)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1.O=C(Cl)C1CC1>>CN(CCN(C)C(=O)C1CC1)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1 -US06703392B2,2,COc1cc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccc2)ccc1O.O=C(Cl)N1CCOCC1>>COc1cc2c(cc1OC)C(Cc1ccc(OC(=O)N3CCOCC3)c(OC)c1)N(CC(=O)NCc1ccccc1)CC2 -US06579874B2,3,C[C@H](Nc1nccc(-n2cc(Br)nc2-c2ccc(F)cc2)n1)c1ccccc1.C[Sn](C)(C)c1ccncc1>>C[C@H](Nc1nccc(-n2cc(-c3ccncc3)nc2-c2ccc(F)cc2)n1)c1ccccc1 -US06642231B2,9,NO.O=C1CCN(CCS(=O)c2ccccc2)CC1>>O=S(CCN1CCC(=NO)CC1)c1ccccc1 -US20120004164A1,1,CCOC(=O)c1sc(N2CCNC2=O)nc1C.Clc1ccc2scc(CBr)c2c1>>CCOC(=O)c1sc(N2CCN(Cc3csc4ccc(Cl)cc34)C2=O)nc1C -US20140309193A1,6,CC(C)(C)OC(=O)C(C)(C)COCCOCCOP(=O)(OCc1ccccc1)OCc1ccccc1>>CC(C)(COCCOCCOP(=O)(OCc1ccccc1)OCc1ccccc1)C(=O)O -US04990511,2,O=C(O)Cc1ccc(OCc2ccccc2)cc1OCc1ccccc1.c1ccc(CN2CCNCC2)cc1>>O=C(Cc1ccc(OCc2ccccc2)cc1OCc1ccccc1)N1CCN(Cc2ccccc2)CC1 -US05948785,2,Nc1ccc[nH]c1=O.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc[nH]c1=O)OCc1ccccc1 -US08003654B2,1,CCN.Cn1cc(C=O)cn1>>CCNCc1cnn(C)c1 -US20100197687A1,4,N#Cc1cc2cc(-c3ccc(C(F)(F)F)cn3)ccc2n1-c1ccc(OC2CCCC2)cc1.[N-]=[N+]=[N-]>>FC(F)(F)c1ccc(-c2ccc3c(c2)cc(-c2nnn[nH]2)n3-c2ccc(OC3CCCC3)cc2)nc1 -US08188113B2,6,CCOC(=O)c1cc(C(C)(C)C)nn1CC(=O)N(C)C>>CN(C)C(=O)Cn1nc(C(C)(C)C)cc1C(=O)O -US20130203714A1,7,Oc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1>>Oc1ccc(C2CCN(C3=Nn4c(nnc4C(F)(F)F)CC3)CC2)cc1 -US20120225854A1,7,O=[N+]([O-])c1csc(S(=O)(=O)N2CCN(c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)c1>>Nc1csc(S(=O)(=O)N2CCN(c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)c1 -US06369060B1,7,Cc1ncccc1Oc1ccc([N+](=O)[O-])cn1>>Cc1ncccc1Oc1ccc(N)cn1 -US20070010537A1,7,COC(=O)c1c(CO[Si](C)(C)C(C)(C)C)cccc1[N+](=O)[O-]>>COC(=O)c1c(N)cccc1CO[Si](C)(C)C(C)(C)C -US05066658,1,CCCCCCCCCCNC(=O)NOCc1ccccc1.CI>>CCCCCCCCCCNC(=O)N(C)OCc1ccccc1 -US20070037812A1,6,COC(=O)CCc1ccc(Oc2cccc(Oc3ccc(Cl)cc3Oc3ccccc3F)c2)cc1C>>Cc1cc(Oc2cccc(Oc3ccc(Cl)cc3Oc3ccccc3F)c2)ccc1CCC(=O)O -US04410534,1,C=[N+]=[N-].O=C(c1ccccc1)c1ccc2n1CCCC2C(=O)O>>COC(=O)C1CCCn2c(C(=O)c3ccccc3)ccc21 -US20130178631A1,3,Brc1ccccn1.C#CCCn1nc2cccc([N+](=O)[O-])c2n1>>O=[N+]([O-])c1cccc2nn(CCC#Cc3ccccn3)nc12 -US05629406,2,CNc1ccc(OCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)C(=O)N2CCC[C@H]2C(=O)NC(C)(C)C)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CN(C(=O)Oc1ccc([N+](=O)[O-])cc1)c1ccc(OCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)C(=O)N2CCC[C@H]2C(=O)NC(C)(C)C)cc1 -US06756373B1,9,BrC(Br)(Br)Br.CCCCOc1ncc(C(=O)CO)cc1-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1>>CCCCOc1ncc(C(=O)CBr)cc1-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1 -US20090069408A1,3,COC(=O)c1cc(F)cc(I)c1-c1c(I)cc(F)cc1C(=O)OC>>COC(=O)c1cc(F)cc2c1-c1c(C(=O)OC)cc(F)cc1-2 -US20120316149A1,7,O=[N+]([O-])c1c(Nc2ccc(I)cc2F)c(F)c(F)c2ccoc12>>Nc1c(Nc2ccc(I)cc2F)c(F)c(F)c2ccoc12 -US07342012B2,6,CC(C)(C)OC(=O)CN1CCN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)C2(Cc2ccc(Br)cc2)C1>>O=C(O)CN1CCN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)C2(Cc2ccc(Br)cc2)C1 -US07199239B2,3,Cc1c(N)cccc1Br.Cc1ccc(B(O)O)cc1>>Cc1ccc(-c2cccc(N)c2C)cc1 -US07582761B2,3,FC(F)(F)c1cccnc1N1CCN(c2nc3ccc(Br)cc3[nH]2)CC1.OB(O)c1ccc(F)c(F)c1>>Fc1ccc(-c2ccc3nc(N4CCN(c5ncccc5C(F)(F)F)CC4)[nH]c3c2)cc1F -US08314100B2,2,CCOC(=O)Nc1nc2cc(F)ccc2nc1OC.COc1cccc(N2CCNCC2)c1>>COc1cccc(N2CCN(C(=O)Nc3nc4cc(F)ccc4nc3OC)CC2)c1 -US20150259346A1,7,O=C1CC(C(F)F)c2ccccc2N1>>FC(F)C1CCNc2ccccc21 -US05972984,6,COC(=O)CN(Cc1ccccc1C)C(C(=O)OC(C)(C)C)[C@@H]1CCCN1>>Cc1ccccc1CN(CC(=O)O)C(C(=O)OC(C)(C)C)[C@@H]1CCCN1 -US20140303164A1,2,CNC.Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)Cn3nc(C(=O)[O-])c4c3C(F)(F)[C@@H]3C[C@H]43)c21>>CN(C)C(=O)c1nn(CC(=O)N[C@@H](Cc2cc(F)cc(F)c2)c2nc(C#CC(C)(C)O)ccc2-c2ccc(Cl)c3c(NS(C)(=O)=O)nn(C)c23)c2c1[C@H]1C[C@H]1C2(F)F -US04067903,1,CCN.Oc1ccc2ccccc2c1>>CCNc1ccc2ccccc2c1 -US04699905,6,CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CSC[C@H](Cc2ccccc2)N(CC(=O)O)C1=O>>O=C(O)CN1C(=O)[C@@H](N[C@@H](CCc2ccccc2)C(=O)O)CSC[C@@H]1Cc1ccccc1 -US08580859B2,6,CSCC[C@@H](CS(=O)(=O)O)NC(=O)CNC(=O)OC(C)(C)C>>CSCC[C@@H](CS(=O)(=O)O)NC(=O)CN -US20070191429A1,2,CCOC(=O)COc1cc(C2CCCNC2)ccc1C.Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)O>>CCOC(=O)COc1cc(C2CCCN(C(=O)c3sc(-c4ccc(C(F)(F)F)cc4)nc3C)C2)ccc1C -US05693651,1,Cc1oc(-c2ccccc2)nc1CCl.O=[N+]([O-])c1cnc2cc(O)ccc2c1>>Cc1oc(-c2ccccc2)nc1COc1ccc2cc([N+](=O)[O-])cnc2c1 -US08003783B2,3,C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O.O=Cc1cccnc1>>CC12CCC3c4ccc(O)cc4CCC3C1CC(=Cc1cccnc1)C2=O -US04024265,7,CCOC(=O)C=C1CCN(C(=O)OCC)CC1Cc1ccccc1>>CCOC(=O)CC1CCN(C(=O)OCC)CC1Cc1ccccc1 -US06849625B2,6,COc1cc2c(Nc3cccc4c(Cl)coc34)ncnc2cc1OCC(CN1CCOCC1)OC(C)=O>>COc1cc2c(Nc3cccc4c(Cl)coc34)ncnc2cc1OCC(O)CN1CCOCC1 -US08461328B2,2,CC1(n2nnc3cnc4c(ccn4S(=O)(=O)c4ccccc4)c32)CCNCC1.O=S(=O)(Cl)c1cccnc1>>CC1(n2nnc3cnc4c(ccn4S(=O)(=O)c4ccccc4)c32)CCN(S(=O)(=O)c2cccnc2)CC1 -US20030229089A1,6,COCOCC1CCCN1C(=O)OCc1ccccc1>>COCOCC1CCCN1 -US08748426B2,2,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(N)cc3)ccc2C1=O.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NS(=O)(=O)c4ccc(C(F)(F)F)cc4)cc3)ccc2C1=O -US20030022887A1,3,CCOC(=O)c1ccc(Cl)nc1.COc1cc(B(O)O)cc(OC)c1OC>>CCOC(=O)c1ccc(-c2cc(OC)c(OC)c(OC)c2)nc1 -US04603139,4,COc1ccc(C(=O)O)c(OCCCCl)c1.Nc1ccncc1N>>COc1ccc(-c2nc3cnccc3[nH]2)c(OCCCCl)c1 -US20140134133A1,3,C#CCO.COc1ncc(-c2ccc3ncc(I)n3c2)cc1NS(=O)(=O)C1CC1>>COc1ncc(-c2ccc3ncc(C#CCO)n3c2)cc1NS(=O)(=O)C1CC1 -US05185342,2,CN.CO/N=C(\C(=O)OC)c1ccccc1Oc1cccc(C)c1>>CNC(=O)/C(=N\OC)c1ccccc1Oc1cccc(C)c1 -US08217177B2,1,Clc1ncnc2nc[nH]c12.NCc1nnc2ccc(-c3ccccc3)nn12>>c1ccc(-c2ccc3nnc(CNc4ncnc5nc[nH]c45)n3n2)cc1 -US03933905,2,CC(C(=O)Cl)c1ccc2c(c1)CCc1ccccc1C2=O.CN>>CNC(=O)C(C)c1ccc2c(c1)CCc1ccccc1C2=O -US04980360,7,COc1cc([N+](=O)[O-])c2nccc(C)c2c1OCCCCCCCc1ccccc1>>COc1cc(N)c2nccc(C)c2c1OCCCCCCCc1ccccc1 -US20150094328A1,6,CC(C)(C)OC(=O)n1cc(C(=O)N[C@H]2CCCC[C@@H]2O)c2ncccc21>>O=C(N[C@H]1CCCC[C@@H]1O)c1c[nH]c2cccnc12 -US20060014746A1,7,CCOC(=O)c1nc2sccn2c1CC>>CCc1c(CO)nc2sccn12 -US20040259859A1,6,COc1ccc(CN2CC3CCC(C2)C3(OC)OC)cc1>>COc1ccc(CN2CC3CCC(C2)C3=O)cc1 -US20060167247A1,3,CC(C)(C)Cl.COC(=O)c1ccc[nH]1>>COC(=O)c1ccc(C(C)(C)C)[nH]1 -US20110112103A1,6,CC(C)(C)OC(=O)c1nc(Cn2ccc(-c3ccc(C(C)(C)C)cc3)cc2=O)nc(O)c1OCc1ccccc1>>CC(C)(C)c1ccc(-c2ccn(Cc3nc(O)c(OCc4ccccc4)c(C(=O)O)n3)c(=O)c2)cc1 -US09115079B2,8,O=C(OCc1ccccc1)C(O)C1CCCC1>>O=C(OCc1ccccc1)C(=O)C1CCCC1 -US20090253689A1,7,N#Cc1cc2nnc(N3CCOCC3)n2cc1-c1ccc(Cl)cc1Cl>>NCc1cc2nnc(N3CCOCC3)n2cc1-c1ccc(Cl)cc1Cl -US06713645B1,6,COC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1ccccc1C(F)(F)F>>NC(=O)c1cccc2c1c1c(OCC(=O)O)cccc1n2Cc1ccccc1C(F)(F)F -US08987256B2,6,CCOC(=O)CCc1cccc(NC(=O)C(c2ccc(CN3N=C(c4ccccc4)OCC3=O)cc2)C2CCCC2)c1>>O=C(O)CCc1cccc(NC(=O)C(c2ccc(CN3N=C(c4ccccc4)OCC3=O)cc2)C2CCCC2)c1 -US20130005743A1,9,COc1ccc(-n2nc(C)c3c(Br)ccnc32)cc1.N#C[Cu]>>COc1ccc(-n2nc(C)c3c(C#N)ccnc32)cc1 -US20150225397A1,5,COc1ccc([C@]23CCC(=O)[C@@H](C)[C@@H]2CCC[C@@H]3O)cc1.OCCO>>COc1ccc([C@]23CCC4(OCCO4)[C@@H](C)[C@@H]2CCC[C@@H]3O)cc1 -US08546112B2,9,CCOC(=O)C(C(=O)OCC)C(CC(C)C)C[N+](=O)[O-]>>CCOC(=O)CC(CC(C)C)C[N+](=O)[O-] -US20090312342A1,1,CC(C)(C)OC(=O)NC1CCNCC1.Oc1ccccc1-c1nc(Cl)c2cc(F)ccc2n1>>CC(C)(C)OC(=O)NC1CCN(c2nc(-c3ccccc3O)nc3ccc(F)cc23)CC1 -US20120282629A1,1,NNc1c(Cl)cc(C(F)(F)F)cc1Cl.O=Cc1c(O)cc(O)cc1O>>Oc1cc(O)c(C=NNc2c(Cl)cc(C(F)(F)F)cc2Cl)c(O)c1 -US06359145B1,7,CCOC(=O)C(CCc1ccccc1)n1cnc(C(N)=O)c1>>NC(=O)c1cn(C(CO)CCc2ccccc2)cn1 -US20090227583A1,2,Cc1noc(C)c1N=C=O.Nc1ccc2nc(N[C@@H]3CCc4ccccc43)ccc2c1>>Cc1noc(C)c1NC(=O)Nc1ccc2nc(N[C@@H]3CCc4ccccc43)ccc2c1 -US20030162790A1,1,ClCc1nc2ccccc2[nH]1.Fc1cccnc1N1CCNCC1>>Fc1cccnc1N1CCN(Cc2nc3ccccc3[nH]2)CC1 -US07737172B2,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Cc1ccc(N)cc1O>>Cc1ccc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1O -US05134111,3,CCc1cccc2cccc(OCOC)c12.CN(C)C=O>>CCc1cccc2ccc(C=O)c(OCOC)c12 -US20140213578A1,9,CS(=O)(=O)OC(CNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)CN1c2ccccc2CCc2ccccc21.[C-]#N>>N#CC(CNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)CN1c2ccccc2CCc2ccccc21 -US20080275043A1,7,COc1ccc(Cl)c(C=O)c1Cl>>COc1ccc(Cl)c(CO)c1Cl -US20140088076A1,1,BrCC1CC1.Cc1ccc(F)cc1-c1ccc2cc(N)ncc2c1>>Cc1ccc(F)cc1-c1ccc2cc(NCC3CC3)ncc2c1 -US20060004087A1,3,COc1ccc(OC)c(B(O)O)c1.COc1ccc2c(=O)c(Br)coc2c1>>COc1ccc(OC)c(-c2coc3cc(OC)ccc3c2=O)c1 -US08114989B2,9,CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)nc(Cl)c2Cl)n[nH]1.[NH4+]>>CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)nc(N)c2Cl)n[nH]1 -US20110212918A1,6,O=C(Nc1cnc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(Nc2ncccn2)c1)OCc1ccccc1>>Nc1cnc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(Nc2ncccn2)c1 -US07951806B2,6,COC(=O)c1cc(Cl)ccc1NC(=O)COCC(=O)Nc1sc(C)c(-c2ccccc2)c1C(=O)OC(C)(C)C>>COC(=O)c1cc(Cl)ccc1NC(=O)COCC(=O)Nc1sc(C)c(-c2ccccc2)c1C(=O)O -US20110034691A1,2,CC(C)(C)n1ncc([C@H](N)C2CC2)c1-c1cc(F)ccc1Br.O=S(=O)(Cl)c1ccc(C(F)(F)F)nc1>>CC(C)(C)n1ncc([C@H](NS(=O)(=O)c2ccc(C(F)(F)F)nc2)C2CC2)c1-c1cc(F)ccc1Br -US09051323B2,1,NCCO.Nc1nc(Cl)ccc1[N+](=O)[O-]>>Nc1nc(NCCO)ccc1[N+](=O)[O-] -US20070287721A1,1,Fc1ccc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(F)c2)cc1.NC1CCCC1>>Fc1ccc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(NC3CCCC3)c2)cc1 -US20070219187A1,2,CC(C)(C)OC(=O)NN.O=C(O)[C@H]1CCCN(C(=O)c2ccc(F)cc2)C1>>CC(C)(C)OC(=O)NNC(=O)[C@H]1CCCN(C(=O)c2ccc(F)cc2)C1 -US20060142336A1,1,Fc1ccc(F)c(CBr)c1.O=S(=O)(/C=C/c1ccccc1)N1CCC(O)CC1>>O=S(=O)(/C=C/c1ccccc1)N1CCC(OCc2cc(F)ccc2F)CC1 -US07723376B2,2,COC(=O)CCC1=CCN(Cc2ccc(N)cc2)C1=O.O=C(Cl)c1ccccc1>>COC(=O)CCC1=CCN(Cc2ccc(NC(=O)c3ccccc3)cc2)C1=O -US20060148858A1,6,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1c(C#N)cccc1CC(=O)OC>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1c(C#N)cccc1CC(=O)O -US09073929B2,3,O=C1CCc2c(Cl)cccc2N1.OB(O)C1CC1>>O=C1CCc2c(cccc2C2CC2)N1 -US20080255216A1,1,NNC(=O)c1ccc2ccccc2c1.O=Cc1ccccc1C(F)(F)F>>O=C(N/N=C/c1ccccc1C(F)(F)F)c1ccc2ccccc2c1 -US05362480,1,CCCCCCCN.OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O>>CCCCCCCNC1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O -US20150274747A1,1,COC1COC2C(OS(C)(=O)=O)COC12.[N-]=[N+]=[N-]>>COC1COC2C(N=[N+]=[N-])COC12 -US20090149456A1,2,CN(C)Cc1cccc(Nc2nccc(-c3c(-c4ccc(F)c(N)c4)nn4ccccc34)n2)c1.O=C(Cl)Cc1cccs1>>CN(C)Cc1cccc(Nc2nccc(-c3c(-c4ccc(F)c(NC(=O)Cc5cccs5)c4)nn4ccccc34)n2)c1 -US20110257198A1,3,C=CB1OC(C)(C)C(C)(C)O1.CCc1cnc(-c2ccc(C)nc2Cl)o1>>C=Cc1nc(C)ccc1-c1ncc(CC)o1 -US05013478,9,BrC(Br)=CC1CCC2(CC1)OCCO2>>C#CC1CCC2(CC1)OCCO2 -US07504522B2,1,C1COCCN1.CC(C)(C)NC(=O)N1CC(OCc2cccc(-c3ccc(CCl)cc3)c2C(F)(F)F)C1>>CC(C)(C)NC(=O)N1CC(OCc2cccc(-c3ccc(CN4CCOCC4)cc3)c2C(F)(F)F)C1 -US20030004165A1,2,CC(C)(C)C(=O)Cl.Nc1ccnc(Cl)c1>>CC(C)(C)C(=O)Nc1ccnc(Cl)c1 -US20060160832A1,7,COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccccc4)cc3)c2cc1C#N>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccccc4)cc3)c2cc1CN -US20040224959A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)c1ccnc(Cl)c1C>>CCOC(=O)c1ccnc(N2CCN(C(=O)OC(C)(C)C)CC2)c1C -US20040097563A1,6,CC(C)(C)[Si](C)(C)Oc1ccccc1-c1cc(-c2cccc(NC(=O)C3CCC(=O)O3)c2)c(C#N)c(N)n1>>N#Cc1c(-c2cccc(NC(=O)C3CCC(=O)O3)c2)cc(-c2ccccc2O)nc1N -US20110105514A1,8,OCCCc1cccc(OC(F)F)c1>>O=CCCc1cccc(OC(F)F)c1 -US09108939B2,1,Nc1ccc2c(c1)ncn2C1CCNCC1.OC(c1ccc(CBr)cc1)(C(F)(F)F)C(F)(F)F>>Nc1ccc2c(c1)ncn2C1CCN(Cc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1 -US08754114B2,2,CC(C(=O)O)n1cc(-c2cnn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)cn1.COC1CCNCC1>>COC1CCN(C(=O)C(C)n2cc(-c3cnn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CC1 -US20070197558A1,1,Cc1ccc(F)c([N+](=O)[O-])c1.Oc1ccc(O)cc1>>Cc1ccc(Oc2ccc(O)cc2)c([N+](=O)[O-])c1 -US20120071505A1,1,COCCCBr.COc1cccc2c(S(=O)(=O)Cc3ccoc3)c(C(=O)O)cnc12>>COCCCOC(=O)c1cnc2c(OC)cccc2c1S(=O)(=O)Cc1ccoc1 -US08486950B2,1,CC(C)c1cc(Nc2cc(NC(=O)c3c(Cl)cccc3Cl)ccn2)nc(Cl)n1.CS(=O)(=O)N1CCNCC1>>CC(C)c1cc(Nc2cc(NC(=O)c3c(Cl)cccc3Cl)ccn2)nc(N2CCN(S(C)(=O)=O)CC2)n1 -US20100249229A1,8,O[C@@H]1C[C@@H]2CC3(OCCO3)[C@@H]2C1>>O=C1C[C@@H]2CC3(OCCO3)[C@@H]2C1 -US07977343B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@H]1CCCN1>>COC(=O)[C@H]1CCCN1C(=O)OC(C)(C)C -US20050085509A1,7,Nc1c(Cl)cc(C(=O)O)cc1Cl>>Nc1c(Cl)cc(CO)cc1Cl -US05179112,1,CI.COc1cc(C#N)ccc1Cc1c[nH]c2ccc([N+](=O)[O-])cc12>>COc1cc(C#N)ccc1Cc1cn(C)c2ccc([N+](=O)[O-])cc12 -US07910595B2,7,Cc1cc([N+](=O)[O-])c(Sc2ccc(O)cc2)cc1NC(=O)Cc1ccccc1>>Cc1cc(N)c(Sc2ccc(O)cc2)cc1NC(=O)Cc1ccccc1 -US08697685B2,6,Clc1ccccc1-c1c[nH]c(C2CN(Cc3ccccc3)CCO2)n1>>Clc1ccccc1-c1c[nH]c(C2CNCCO2)n1 -US07671043B2,6,COC(=O)c1ccc(CO)nc1>>O=C(O)c1ccc(CO)nc1 -US20150266819A1,7,COc1cc(OC)c(/C=C/S(=O)(=O)Cc2ccc(OC)c(O)c2)c(OC)c1>>COc1cc(OC)c(CCS(=O)(=O)Cc2ccc(OC)c(O)c2)c(OC)c1 -US07994164B2,1,CC(C)(C)OC(=O)N1CC[C@@H](N)[C@H](O)C1.O=Cc1ccccc1>>CC(C)(C)OC(=O)N1CC[C@@H](NCc2ccccc2)[C@H](O)C1 -US20090209522A1,6,COc1cc2c(cc1Oc1nc(C(=O)Nc3c(OC)nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc3OC)cs1)C(C)(C)CC2>>COc1cc2c(cc1Oc1nc(C(=O)Nc3c(OC)nc(NCCNC(C)C)nc3OC)cs1)C(C)(C)CC2 -US08809538B2,2,N#Cc1c(N)cc(C(=O)O)nc1Cl.NCC1CCN(Cc2cnc(-c3ccccn3)s2)CC1>>N#Cc1c(N)cc(C(=O)NCC2CCN(Cc3cnc(-c4ccccn4)s3)CC2)nc1Cl -US20030144283A1,2,COCCc1nc2c(N)nc3ccccc3c2n1CCCN.O=C(Cl)c1ccccc1>>COCCc1nc2c(N)nc3ccccc3c2n1CCCNC(=O)c1ccccc1 -US20060217346A1,2,CC#CC(C)(C)N.CCOC(Oc1cc(Cl)cc(Cl)c1)C(=O)O>>CC#CC(C)(C)NC(=O)C(OCC)Oc1cc(Cl)cc(Cl)c1 -US04758559,1,CC1(C=O)OCc2ccccc2-n2cccc21.O=C1NCCN1C1CCNCC1>>CC1(CN2CCC(N3CCNC3=O)CC2)OCc2ccccc2-n2cccc21 -US06333198B1,1,N#CC(=O)c1cccc(Cl)c1Cl.N=C(N)NN>>N#C/C(=N\NC(=N)N)c1cccc(Cl)c1Cl -US20030225081A1,1,CN(C)CCCl.O=C1N(c2ccccc2)CC(c2ccccc2O)=NN1c1ccccc1Br>>CN(C)CCOc1ccccc1C1=NN(c2ccccc2Br)C(=O)N(c2ccccc2)C1 -US08987314B2,3,CCOC(=O)Cc1nc2ccc(Br)cc2s1.OB(O)c1ccnc(F)c1>>CCOC(=O)Cc1nc2ccc(-c3ccnc(F)c3)cc2s1 -US07741341B2,6,COC(=O)c1cccc2c1nc(C(=O)Nc1ccc(N3CCOCC3=O)cc1)n2CC(=O)Nc1ccc(Cl)cn1>>O=C(Cn1c(C(=O)Nc2ccc(N3CCOCC3=O)cc2)nc2c(C(=O)O)cccc21)Nc1ccc(Cl)cn1 -US20110224258A1,1,CNN.O=C(CCl)N1CCC(c2nc(C3=NOC(c4c(F)cccc4F)C3)cs2)CC1>>CN(N)CC(=O)N1CCC(c2nc(C3=NOC(c4c(F)cccc4F)C3)cs2)CC1 -US08415345B2,1,CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(Cl)n2)s1.NC1CC1>>CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(NC3CC3)n2)s1 -US20080280991A1,9,COc1ccc2cccc(CC(N)=O)c2c1>>COc1ccc2cccc(CC#N)c2c1 -US07018998B2,2,CC(C)(C)OC(=O)Nc1ccc(-c2cc(F)ccc2F)cc1N.CCOC(=O)CC(=O)c1cccc(-n2ccnn2)c1>>CC(C)(C)OC(=O)Nc1ccc(-c2cc(F)ccc2F)cc1NC(=O)CC(=O)c1cccc(-n2ccnn2)c1 -US07468393B2,7,O=S(=O)(c1ccc(F)cc1)c1ccc(/C=C/c2ccc(F)cc2)nc1>>O=S(=O)(c1ccc(F)cc1)c1ccc(CCc2ccc(F)cc2)nc1 -US20140155406A1,2,C=CS(=O)(=O)Cl.CCCc1ccnc(NC(=O)c2ccc(-c3nc([C@@H]4CCCCN4)n4ccnc(C)c34)cc2)c1>>C=CS(=O)(=O)N1CCCC[C@H]1c1nc(-c2ccc(C(=O)Nc3cc(CCC)ccn3)cc2)c2c(C)nccn12 -US20050054712A1,1,COc1cccc(B(O)O)c1.O=C1Nc2ccccc2C1=O>>COc1cccc(N2C(=O)C(=O)c3ccccc32)c1 -US08895050B2,2,COC(=O)[C@H](N)CC(C)C.Cc1ccc2[nH]c(C(=O)O)cc2c1>>COC(=O)[C@@H](CC(C)C)NC(=O)c1cc2cc(C)ccc2[nH]1 -US06174961B1,1,CCCCNc1cccc(O)c1.OCCBr>>CCCCN(CCO)c1cccc(O)c1 -US20080090818A1,3,Brc1cnc(Nc2ccc(N3CCOCC3)cc2)c2ncnn12.CC1(C)OB(c2csc(C(N)=O)c2)OC1(C)C>>NC(=O)c1cc(-c2cnc(Nc3ccc(N4CCOCC4)cc3)c3ncnn23)cs1 -US06413995B1,6,CCOC(=O)COc1ccc(C(=CC(=O)NCc2cccnc2)c2ccccc2)cc1>>O=C(O)COc1ccc(C(=CC(=O)NCc2cccnc2)c2ccccc2)cc1 -US20120264777A1,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Cc1nc(Br)ccc1F>>C=C(OCC)c1ccc(F)c(C)n1 -US20050119225A1,6,CC(C)(C)OC(=O)c1ccc(N(Cc2cccnc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1>>O=C(O)c1ccc(N(Cc2cccnc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 -US20110082155A1,2,CCOC(=O)c1cc(-c2ccnn2-c2ccc(C#N)cc2)c(C)n(-c2cccc(C(F)(F)F)c2)c1=O.NCCCCN1CCCC1>>Cc1c(-c2ccnn2-c2ccc(C#N)cc2)cc(C(=O)NCCCCN2CCCC2)c(=O)n1-c1cccc(C(F)(F)F)c1 -US20140336198A1,3,CC1(C)Oc2ccccc2S1.O=C(Cl)C1CC1>>CC1(C)Oc2ccc(C(=O)C3CC3)cc2S1 -US05217645,1,CCCCCCCCc1ccc(C(=O)O)s1.CCCC[Si](C)(C)CCCOc1ccc(O)cc1>>CCCCCCCCc1ccc(C(=O)Oc2ccc(OCCC[Si](C)(C)CCCC)cc2)s1 -US20080234301A1,7,COC(=O)C[C@@H](C)c1ccc(Cn2c(C)nc(C)c(-c3ccc([N+](=O)[O-])cc3)c2=O)cc1>>COC(=O)C[C@@H](C)c1ccc(Cn2c(C)nc(C)c(-c3ccc(N)cc3)c2=O)cc1 -US20110301176A1,1,COC(=O)[C@H](N)CC(C)C.O=CC1(NC(=O)OCc2ccccc2)CC1>>COC(=O)[C@@H](CC(C)C)NCC1(NC(=O)OCc2ccccc2)CC1 -US20060194809A1,2,O=C(Cl)c1ccccc1.O=Cc1ccc(CCO)cc1>>O=Cc1ccc(CCOC(=O)c2ccccc2)cc1 -US05340802,3,C=C[Mg+].CC(C)(C)OC(=O)NCC=O>>C=CC(O)CNC(=O)OC(C)(C)C -US20020177578A1,9,CC(=O)OC[C@H]1O[C@H](OC(C)=O)[C@H](N=[N+]=[N-])[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@H]1O[C@H](OC(C)=O)[C@H](N)[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US20140100231A1,1,COc1ccc(Cn2cnc(C(F)(F)F)c(Br)c2=O)cc1.N#Cc1cc(O)cc(O)c1>>COc1ccc(Cn2cnc(C(F)(F)F)c(Oc3cc(O)cc(C#N)c3)c2=O)cc1 -US07985491B2,3,Brc1ccc(I)cc1.OB(O)c1ccc2cc(-c3cccc4ccccc34)ccc2c1>>Brc1ccc(-c2ccc3cc(-c4cccc5ccccc45)ccc3c2)cc1 -US06180622B2,3,C=CCOC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1C=O.c1ccc([P+](Cc2cn3cncc3s2)(c2ccccc2)c2ccccc2)cc1>>C=CCOC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1C=Cc1cn2cncc2s1 -US07855294B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccccc1[C@H]1CCNC[C@@H]1O>>Cc1ccccc1[C@H]1CCN(C(=O)OC(C)(C)C)C[C@@H]1O -US20040102636A1,1,Cc1ccc(O)cc1.O=[N+]([O-])c1ccc(Cl)nc1>>Cc1ccc(Oc2ccc([N+](=O)[O-])cn2)cc1 -US20110130433A1,3,CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1.CC(C)(C)OC(=O)n1nc(N)c2ccc(Br)cc21>>CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc4c(N)nn(C(=O)OC(C)(C)C)c4c3)cc2)[nH]1 -US20090318477A1,1,CC(C)(C)COC(=O)N1CCC(O)CC1.CS(=O)(=O)c1ccc(N2CCc3c(Cl)ncnc32)c(F)c1>>CC(C)(C)COC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(S(C)(=O)=O)cc2F)CC1 -US04053509,2,Nc1ccc(C(F)(F)F)cc1.O=C(O)C12CC3CC(CC(C3)C1)C2>>O=C(Nc1ccc(C(F)(F)F)cc1)C12CC3CC(CC(C3)C1)C2 -US04791106,1,C1COCCN1.OCCCBr>>OCCCN1CCOCC1 -US20100285145A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Cc1c(Cl)ncnc1Cl>>Cc1c(Cl)ncnc1OC1CCN(C(=O)OC(C)(C)C)CC1 -US08044069B2,2,NC1CCCc2ccccc21.O=C(O)CN1CCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCC(c2ccccc2)(c2ccccc2)C1=O)NC1CCCc2ccccc21 -US08268822B2,1,CC=O.CCN(CC)CCCNCc1cccc(-c2ccnc(NCCc3ccc(O)cc3)n2)c1>>CCN(CC)CCCN(CC)Cc1cccc(-c2ccnc(NCCc3ccc(O)cc3)n2)c1 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.CC(C)CCOc1ccc2ccccc2c1C=O>>CC(C)CCOc1ccc2ccccc2c1CN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1 -US20130131075A1,1,CC(C)Oc1ccc(N)c(C(F)(F)F)c1.N#Cc1ccc(F)cc1>>CC(C)Oc1ccc(Nc2ccc(C#N)cc2)c(C(F)(F)F)c1 -US20070254872A1,1,CN.O=Cc1ccc2c(n1)NC(=O)CS2>>CNCc1ccc2c(n1)NC(=O)CS2 -US20080045526A1,1,CCC1OC(=C2C(=O)Nc3ccc(F)cc32)c2cnc(Cl)c(Cl)c21.NCCN1CCOCC1>>CCC1OC(=C2C(=O)Nc3ccc(F)cc32)c2cnc(NCCN3CCOCC3)c(Cl)c21 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](C(C)C)NC1=O.O=C(O)c1cc(-c2cccs2)on1>>CC(C)C[C@H]1C(=O)N[C@@H](C(C)C)CN1C(=O)c1cc(-c2cccs2)on1 -US08481550B2,9,CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](Oc2cc(Cl)ncn2)C[C@@H]1O[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](Oc2ccncn2)C[C@@H]1O[Si](C)(C)C(C)(C)C -US20080269170A1,1,CC(C)(C)OC(=O)N1CC(=O)C1.NCCN1CCCC1>>CC(C)(C)OC(=O)N1CC(NCCN2CCCC2)C1 -US20120263753A1,7,COc1ccc(C#Cc2cnc3c(N)nc4cc(C)ccc4c3c2)c(C)c1>>COc1ccc(CCc2cnc3c(N)nc4cc(C)ccc4c3c2)c(C)c1 -US04180584,9,COC(=O)C1CC(C#N)(c2ccccc2Cl)CCC1=O>>N#CC1(c2ccccc2Cl)CCC(=O)CC1 -US20110201592A1,6,COC(=O)[C@H]1C[C@H](Nc2nc(-c3ccccc3OC)nc3ccccc23)CN1C(=O)OC(C)(C)C>>COc1ccccc1-c1nc(N[C@H]2C[C@H](C(=O)O)N(C(=O)OC(C)(C)C)C2)c2ccccc2n1 -US20090012074A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCc2cc(Br)ccc2C1>>CC(C)(C)OC(=O)N[C@@H]1CCc2cc(Br)ccc2C1 -US20140066426A1,6,CCOC(=O)c1[nH]ccc1-c1ccc(Cl)cc1>>O=C(O)c1[nH]ccc1-c1ccc(Cl)cc1 -US20080194535A1,1,C=CCBr.COc1ccc2c(c1)[C@@H](NC(=O)C(F)(F)F)[C@@H](O)C2>>C=CCO[C@H]1Cc2ccc(OC)cc2[C@H]1NC(=O)C(F)(F)F -US20140235689A1,9,Cc1nn(C)c(C(Cl)c2ccc(F)cc2F)c1-c1c(F)cccc1F.N>>Cc1nn(C)c(C(N)c2ccc(F)cc2F)c1-c1c(F)cccc1F -US20080027049A1,2,CCCCCCC(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCCC3>>CCCCCCC(=O)Nc1ccc2oc3c(c2c1)CCCCCC3 -US20150232473A1,2,COc1ccc2c(c1)C(=O)N1CCC[C@H]1c1c(C(=O)O)ncn1-2.NC1CC1>>COc1ccc2c(c1)C(=O)N1CCC[C@H]1c1c(C(=O)NC3CC3)ncn1-2 -US05608056,3,C=CCOC(=O)N1C[C@@H](C(C)(C)C)C[C@@]1(C=O)O[SiH](C)C.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>C=CCOC(=O)N1C[C@@H](C(C)(C)C)C[C@@]1(C=CC(=O)OC)O[SiH](C)C -US20140228361A1,7,COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC(C)=O>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1O -US04461906,6,COc1ccc(C(=O)N2CCCC2=O)cc1OCc1ccccc1>>COc1ccc(C(=O)N2CCCC2=O)cc1O -US20010016207A1,1,CC(C)N1CCNCC1.COC(=O)c1ccc(Br)cc1>>COC(=O)c1ccc(N2CCN(C(C)C)CC2)cc1 -US20110105566A1,8,Cc1nc(Br)ccc1F.O=C(OO)c1cccc(Cl)c1>>Cc1c(F)ccc(Br)[n+]1[O-] -US06486325B1,6,COc1ccc(C(C)(O[Si](C)(C)C)C(F)(F)F)c(CCOC(C)=O)c1>>COc1ccc(C(C)(O)C(F)(F)F)c(CCOC(C)=O)c1 -US05472958,1,CC(C)(C)OC(=O)N1CCC[C@@H]1CO.O=[N+]([O-])c1cccc(O)c1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cccc([N+](=O)[O-])c1 -US04863947,2,COC(=O)C(C)(CO)C(=O)c1ccc(Cl)cc1.CS(=O)(=O)Cl>>COC(=O)C(C)(COS(C)(=O)=O)C(=O)c1ccc(Cl)cc1 -US20110212956A1,2,CC1NCCc2cc(-c3ccc(F)nc3)ccc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2ccc(-c3ccc(F)nc3)cc2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US08153818B2,9,CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(F)c(Cl)cc2C(=O)Cl)cc1.NN>>CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(F)c(Cl)cc2C(=O)NN)cc1 -US20020035266A1,3,COC(=O)/C(I)=C\C1CCCCC1.Cc1nnnn1-c1ccc(I)cc1Cl>>COC(=O)/C(=C/C1CCCCC1)c1ccc(-n2nnnc2C)c(Cl)c1 -US20130289058A1,3,CCc1nc(C)c(C(=O)Nc2ccc(Br)cc2)o1.COC(=O)CC12CCC(c3ccc(B4OC(C)(C)C(C)(C)O4)cc3)(CC1)OC2>>CCc1nc(C)c(C(=O)Nc2ccc(-c3ccc(C45CCC(CC(=O)OC)(CC4)CO5)cc3)cc2)o1 -US06506911B2,1,BrCc1ccccc1.O=c1ccoc(CO)c1O>>O=c1ccoc(CO)c1OCc1ccccc1 -US20070106081A1,7,COC(=O)c1ccc2cn(-c3ccc(C(F)(F)F)cc3)nc2c1>>OCc1ccc2cn(-c3ccc(C(F)(F)F)cc3)nc2c1 -US06384051B1,7,N#Cc1cnc2ccc([N+](=O)[O-])cc2c1Nc1ccc(Sc2ccccc2)c(Cl)c1>>N#Cc1cnc2ccc(N)cc2c1Nc1ccc(Sc2ccccc2)c(Cl)c1 -US06306874B1,8,CC(C)(C)OC(=O)n1c(-c2cc3ccccc3[nH]c2=O)cc2cc(CO)ccc21>>CC(C)(C)OC(=O)n1c(-c2cc3ccccc3[nH]c2=O)cc2cc(C=O)ccc21 -US08017779B2,1,CCOCc1nc2c(N)nc3cc(Br)ccc3c2n1CCCOC(C)C.O=c1cccc[nH]1>>CCOCc1nc2c(N)nc3cc(-n4ccccc4=O)ccc3c2n1CCCOC(C)C -US20080027049A1,7,O=C(Nc1ccc2oc3c(c2c1)CCCC3)c1ccc([N+](=O)[O-])cc1>>Nc1ccc(C(=O)Nc2ccc3oc4c(c3c2)CCCC4)cc1 -US20100004249A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)Nc2cccnc2)C(CO)C1>>CC(C)(C)OC(=O)N1CCN2C(=O)N(c3cccnc3)CC2C1 -US20070232607A1,6,Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@H](C)C(=O)N5CCN(C(=O)OC(C)(C)C)CC5)c34)cc2C)cn1>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@H](C)C(=O)N5CCNCC5)c34)cc2C)cn1 -US07250424B2,2,CNCc1c2n(c3ccccc13)CCC2.O=C(O)/C=C/c1cnc2c(c1)CCC(=O)N2>>CN(Cc1c2n(c3ccccc13)CCC2)C(=O)/C=C/c1cnc2c(c1)CCC(=O)N2 -US20020165264A1,9,O=C(Cl)COc1ccccc1.[NH4+]>>NC(=O)COc1ccccc1 -US20100028445A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCSSCCN>>CC(C)(C)OC(=O)NCCSSCCN -US06977264B2,2,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2N)CC1.N#Cc1ccccc1S(=O)(=O)Cl>>CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2NS(=O)(=O)c2ccccc2C#N)CC1 -US05260285,7,CCOC(=O)c1c(CC)nc2c(C)cc(C)nn12>>CCc1nc2c(C)cc(C)nn2c1CO -US20120077781A1,1,Cc1cc(N)c([N+](=O)[O-])cc1C.O=C1CCCC(CCBr)O1>>Cc1cc(NCCC2CCCC(=O)O2)c([N+](=O)[O-])cc1C -US04933355,7,CCOC(=O)c1csc(NCc2ccccc2)n1>>OCc1csc(NCc2ccccc2)n1 -US20130065934A1,2,CC(C)(C)OC(=O)NCCSSCCN.COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1>>COc1ccc2c(c1)c(CC(=O)NCCSSCCNC(=O)OC(C)(C)C)c(C)n2C(=O)c1ccc(Cl)cc1 -US05324722,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ccc2c(c1)NCc1ccccc1O2>>CC(C)(C)OC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 -US06255307B1,9,N.Nc1nc(Cl)cnc1-c1cccc(Cl)c1Cl>>Nc1cnc(-c2cccc(Cl)c2Cl)c(N)n1 -US04405810,1,Cc1ccc(S(=O)(=O)NN)cc1.O=C1CCCC(=O)C1Cc1ccccc1>>Cc1ccc(S(=O)(=O)NN=C2CCCC(=O)C2Cc2ccccc2)cc1 -US20110077399A1,1,COC(=O)CBr.COc1ccc(/C=C/c2nc(-c3ccc(-c4ccccc4)cc3)c[nH]2)cc1>>COC(=O)Cn1cc(-c2ccc(-c3ccccc3)cc2)nc1/C=C/c1ccc(OC)cc1 -US06727264B1,1,C[C@@H](CCl)CBr.Oc1cccc(Cl)c1>>C[C@@H](CCl)COc1cccc(Cl)c1 -US06248753B1,1,Cc1cc(C)c(-n2nc(C)c3c(Cl)cc(C)nc32)c(C)c1.OC1CCOC1>>Cc1cc(C)c(-n2nc(C)c3c(OC4CCOC4)cc(C)nc32)c(C)c1 -US20080146570A1,7,O=C(O)c1cc(F)cc(Br)c1>>OCc1cc(F)cc(Br)c1 -US20100179128A1,6,CCCCCn1c(=O)n(CCCc2cccc(OC)c2)c(=O)c2[nH]c(Cl)nc21>>CCCCCn1c(=O)n(CCCc2cccc(O)c2)c(=O)c2[nH]c(Cl)nc21 -US20060069085A1,2,CCOC(=O)c1nn(-c2ccccc2)c(C(=O)Nc2ccccc2)c1CCO.CS(=O)(=O)Cl>>CCOC(=O)c1nn(-c2ccccc2)c(C(=O)Nc2ccccc2)c1CCOS(C)(=O)=O -US07968720B2,6,CNC(=O)Cc1ccc(Cl)c(CN(C(=O)OC(C)(C)C)C2CC2)c1>>CNC(=O)Cc1ccc(Cl)c(CNC2CC2)c1 -US20090099169A1,2,Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12.Nc1ccc(CO)cc1>>Cc1cc(C(=O)Nc2ccc(CO)cc2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 -US07781431B2,7,COC(=O)c1cc(-c2ccccc2)n(Cc2ccccc2)c1Cl>>OCc1cc(-c2ccccc2)n(Cc2ccccc2)c1Cl -US20090221555A1,1,CCCNC(=O)c1ccccc1N.Clc1ncc(Cl)c(Cl)n1>>CCCNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl -US05716956,6,CC(=O)Nc1ccc(C2=NN(C(=O)N(C)C)C(C)c3cc4c(cc32)OCO4)cc1>>CC1c2cc3c(cc2C(c2ccc(N)cc2)=NN1C(=O)N(C)C)OCO3 -US06780869B1,3,CSc1ccc(B(O)O)cc1.CSc1nc(Cl)cc(C(F)(F)F)n1>>CSc1ccc(-c2cc(C(F)(F)F)nc(SC)n2)cc1 -US20130196990A1,6,COC(=O)c1cc(N2CCOCC2)cc2c1nc(C(F)(F)F)n2Cc1cccc(Cl)c1Cl>>O=C(O)c1cc(N2CCOCC2)cc2c1nc(C(F)(F)F)n2Cc1cccc(Cl)c1Cl -US20110207704A1,6,COC(=O)[C@H]1C[C@@H](Nc2ccc(-c3nc(-c4ccc(OC(C)C)c(Cl)c4)no3)cc2)CN1C(=O)OC(C)(C)C>>CC(C)Oc1ccc(-c2noc(-c3ccc(N[C@@H]4C[C@H](C(=O)O)N(C(=O)OC(C)(C)C)C4)cc3)n2)cc1Cl -US20130150364A1,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2cc(-n3c(C(F)F)nc4ccccc43)nc(N3CCOCC3)n2)CC1.CC(C)CBr>>CC(C)CN(c1cc(-n2c(C(F)F)nc3ccccc32)nc(N2CCOCC2)n1)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1 -US20080269250A1,1,CCN1CCCC(=O)C1.OC1(C#Cc2cccc(Cl)c2)CCNCC1>>CCN1CCCC(N2CCC(O)(C#Cc3cccc(Cl)c3)CC2)C1 -US07700640B2,1,CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)cc1.C[C@H](O)COC(C)(C)C>>C[C@@H](COC(C)(C)C)Oc1cc(C#N)cc(Oc2ccc(S(C)(=O)=O)cc2)c1 -US06265446B1,2,CC(C)CNN.CC(C)C[C@@H](C(=O)O)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C>>CC(C)CNNC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C -US04473632,1,CC(=O)O.CCCCCCCCCCCCCCCCOc1cc(NS(=O)(=O)c2cc([N+](=O)[O-])ccc2N2CCOCC2)c(O)cc1C(C)(C)CC(C)(C)C>>CCCCCCCCCCCCCCCCOc1cc(NS(=O)(=O)c2cc([N+](=O)[O-])ccc2N2CCOCC2)c(OC(C)=O)cc1C(C)(C)CC(C)(C)C -US20080070948A1,1,ClCCCI.O=c1[nH]c2cc(F)ccc2o1>>O=c1oc2ccc(F)cc2n1CCCCl -US06455531B1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Oc1ccc2ccccc2c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc3ccccc3c2)CC1 -US08247429B2,7,CC(=O)NCC=C1CCc2c(F)cc3nn(C)cc3c21>>CC(=O)NCCC1CCc2c(F)cc3nn(C)cc3c21 -US20080255358A1,3,COc1ncccc1B(O)O.Cc1cccc(C)c1CNc1cc(Br)cn2c(C)c(C)nc12>>COc1ncccc1-c1cc(NCc2c(C)cccc2C)c2nc(C)c(C)n2c1 -US07208495B2,9,COc1ccc(C2CCN(c3c(C)c(C)c4c(c3C)C(O)(c3ccccc3)C(C)(C)O4)CC2)cc1OC>>COc1ccc(C2CCN(c3c(C)c(C)c4c(c3C)C(c3ccccc3)C(C)(C)O4)CC2)cc1OC -US20050261333A1,7,Cc1c(Cl)cnc(N)c1[N+](=O)[O-]>>Cc1c(Cl)cnc(N)c1N -US06982348B2,6,CCOC(=O)C(Cc1ccc(CC(C)(C)C)cc1)C(O)c1cccc(Cl)c1>>CC(C)(C)Cc1ccc(CC(C(=O)O)C(O)c2cccc(Cl)c2)cc1 -US07569578B2,6,COC(=O)C(Cc1cc(C)c2[nH]ncc2c1)NC(=O)N1CCC(N2Cc3cccc(F)c3NC2=O)CC1>>Cc1cc(CC(NC(=O)N2CCC(N3Cc4cccc(F)c4NC3=O)CC2)C(=O)O)cc2cn[nH]c12 -US20130261128A1,3,COC(=O)C(C)(C)COc1cc(C)c(B2OC(C)(C)C(C)(C)O2)cn1.C[Si](C)(C)CCOCn1cc(C(F)(F)F)nc1-c1ccc(Br)cn1>>COC(=O)C(C)(C)COc1cc(C)c(-c2ccc(-c3nc(C(F)(F)F)cn3COCC[Si](C)(C)C)nc2)cn1 -US20090270361A1,6,COC(=O)c1ccc(Cc2c(C)nn(-c3ccc(Br)c(Cl)c3)c2C)cc1>>Cc1nn(-c2ccc(Br)c(Cl)c2)c(C)c1Cc1ccc(C(=O)O)cc1 -US20140187769A1,7,COC(=O)[C@@H]1Cc2cc([N+](=O)[O-])c(O)cc2CN1C(=O)OC(C)C>>COC(=O)[C@@H]1Cc2cc(N)c(O)cc2CN1C(=O)OC(C)C -US20100240653A1,1,CS(=O)(=O)OCCc1ccc(Br)cc1.C[C@@H]1CCCN1>>C[C@@H]1CCCN1CCc1ccc(Br)cc1 -US08188082B2,1,COC(=O)CBr.Oc1ccc(C(F)(F)F)cc1>>COC(=O)COc1ccc(C(F)(F)F)cc1 -US20130267524A1,1,CC(Br)c1nc2ccc(F)cc2nc1Cl.O=C1NC(=O)c2ccccc21>>CC(c1nc2ccc(F)cc2nc1Cl)N1C(=O)c2ccccc2C1=O -US04309435,2,Cc1[nH]cnc1CSCCN.N=C(N)Nc1nc(CSCCN=C=S)cs1>>Cc1[nH]cnc1CSCCNC(=S)NCCSCc1csc(NC(=N)N)n1 -US04619917,6,CCCCCCCCCCCCCCCCCCOCCC1(COCc2ccccc2)CCC(=O)O1>>CCCCCCCCCCCCCCCCCCOCCC1(CO)CCC(=O)O1 -US07179912B2,1,C1COCCN1.O=[N+]([O-])c1ccc(Cl)cc1CO>>O=[N+]([O-])c1ccc(N2CCOCC2)cc1CO -US07183278B1,6,COC(=O)c1ncc(OC)c(OC)c1OCc1ccccc1>>COc1cnc(C(=O)O)c(OCc2ccccc2)c1OC -US06855722B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc2c(n1)NCCO2>>Cc1ccc2c(n1)N(C(=O)OC(C)(C)C)CCO2 -US20090105212A1,1,CCCCOc1nc(N)c2ncn(Cc3ccc(Cl)nc3)c2n1.OCCO>>CCCCOc1nc(N)c2ncn(Cc3ccc(OCCO)nc3)c2n1 -US20100094041A1,3,C=Cc1cc(OC)c(CCC)c(OC)c1.Fc1cc(F)c(Br)c(F)c1>>CCCc1c(OC)cc(C=Cc2c(F)cc(F)cc2F)cc1OC -US20110136801A1,1,COC(=O)C1(Oc2cccc(C=O)c2)CC1.COCCc1nc2c(N)nc3ccccc3c2n1CCCN>>COCCc1nc2c(N)nc3ccccc3c2n1CCCNCc1cccc(OC2(C(=O)OC)CC2)c1 -US04741764,2,Cc1cc(C)n2nc(S(=O)(=O)Cl)nc2n1.Cc1cccc(C)c1N>>Cc1cc(C)n2nc(S(=O)(=O)Nc3c(C)cccc3C)nc2n1 -US08327467B2,1,CC(C)(C)OC(=O)c1ccc(CCc2ccccc2)cc1N.FC(F)(F)Oc1ccc(Br)cc1>>CC(C)(C)OC(=O)c1ccc(CCc2ccccc2)cc1Nc1ccc(OC(F)(F)F)cc1 -US20110237784A1,2,Nc1cccc(O)c1.O=C(Cl)C1CCCC1>>O=C(Nc1cccc(O)c1)C1CCCC1 -US20010036941A1,1,CCOC(=O)c1cc(=O)c2cc(F)c(F)c(C#N)c2n1C1CC1.NCC12CNCC1CCO2>>CCOC(=O)c1cc(=O)c2cc(F)c(N3CC4CCOC4(CN)C3)c(C#N)c2n1C1CC1 -US20060160864A1,2,CCCCOCCOc1ccc(-c2ccc(N(C)Cc3cnn(C)c3)c(/C=C/C(=O)O)c2)cc1.CCCn1cncc1C[S@](=O)c1ccc(N)cc1>>CCCCOCCOc1ccc(-c2ccc(N(C)Cc3cnn(C)c3)c(/C=C/C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1 -US20050282863A1,1,COc1ccc2c(c1)SCCc1c-2[nH]c2ccc(OC)cc12.ClCCCCCBr>>COc1ccc2c(c1)SCCc1c-2n(CCCCCCl)c2ccc(OC)cc12 -US20120083489A1,1,CCNCCN.O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(F)nc1>>CCNCCNc1ccc(-n2ccc(OCc3ccc(Cl)cn3)cc2=O)cn1 -US20090082379A1,1,CC(=O)N1CC(C)(C)c2ccc(N3C(=O)NC(C)(C)C3=O)cc21.ClCc1ccnc(Cl)c1>>CC(=O)N1CC(C)(C)c2ccc(N3C(=O)N(Cc4ccnc(Cl)c4)C(C)(C)C3=O)cc21 -US20050288376A1,6,O=CN(O)[C@H](CS(=O)(=O)CC1Cc2ccccc2C1)c1cccc(NC(=O)OCc2ccccc2)c1>>Nc1cccc([C@@H](CS(=O)(=O)CC2Cc3ccccc3C2)N(O)C=O)c1 -US20070259888A1,2,CCOC[C@H]1CCCN(C[C@H]2CCCC[C@@H]2N)C1.COCCOc1ccc(C(=O)O)cc1>>CCOC[C@H]1CCCN(C[C@H]2CCCC[C@@H]2NC(=O)c2ccc(OCCOC)cc2)C1 -US20120028924A1,1,COc1cc(F)ccc1[N+](=O)[O-].F[C@@H]1CNCC[C@@H]1NCc1ccccc1>>COc1cc(N2CC[C@H](NCc3ccccc3)[C@H](F)C2)ccc1[N+](=O)[O-] -US20150175599A1,6,COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cc3)c3ccc(N(C)C(=O)OC(C)(C)C)cc23)ccn1>>CNc1ccc2c(c1)c(C(=O)C(=O)Nc1ccnc(OC)c1)c(C)n2Cc1ccc(Cl)cc1 -US08557984B2,4,COc1cc2c(N[C@H](C)c3ccccn3)c(N)cnc2cc1-c1c(C)noc1C.O=C(O)C1CCOCC1>>COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(C3CCOCC3)n(C(C)c3ccccn3)c12 -US20110009429A1,2,NS(=O)(=O)c1ccccc1.O=C(O)c1cc2nc(CCc3cccc(F)c3F)cc(O)n2n1>>O=C(NS(=O)(=O)c1ccccc1)c1cc2nc(CCc3cccc(F)c3F)cc(O)n2n1 -US20120238575A1,3,COc1nc(Cl)cc(NN=C(C)c2ccc(N(C)C)cc2)n1.OB(O)c1ccccc1>>COc1nc(NN=C(C)c2ccc(N(C)C)cc2)cc(-c2ccccc2)n1 -US20100041892A1,1,CC(C)I.CCOC(=O)/C(C)=C/c1ccc(O)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CCOC(=O)/C(C)=C/c1ccc(OC(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl -US20110046097A1,7,O=C(O)c1cccc(I)c1F>>OCc1cccc(I)c1F -US07932281B2,1,CCCN(CCC)CCCCNC(=O)c1cn2c(n1)CCC(CN)C2.O=Cc1ncc[nH]1>>CCCN(CCC)CCCCNC(=O)c1cn2c(n1)CCC(CNCc1ncc[nH]1)C2 -US20090131468A1,6,COC(=O)c1ccc2cc(-c3ccccc3)oc2c1>>O=C(O)c1ccc2cc(-c3ccccc3)oc2c1 -US20100256132A1,9,CN(CCOc1cc(Cl)nc(N2CCOCC2)n1)C(=O)OC(C)(C)C.NN>>CN(CCOc1cc(NN)nc(N2CCOCC2)n1)C(=O)OC(C)(C)C -US20140323518A1,6,CCCc1cc(-c2ccc(O)cc2)c(-c2ccccc2)c(-c2cnn(Cc3ccccc3)c2)c1>>CCCc1cc(-c2ccc(O)cc2)c(-c2ccccc2)c(-c2cn[nH]c2)c1 -US20030073836A1,2,Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O.NCc1ccc(C2CCC3(CC2)OCCO3)cc1>>Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)NCc1ccc(C2CCC3(CC2)OCCO3)cc1 -US20050288283A1,3,COc1ccc(OC)cc1.O=C(Cl)c1ccccc1CBr>>COc1ccc(OC)c(C(=O)c2ccccc2CBr)c1 -US20090227560A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1CCOS(C)(=O)=O.CCOC(=O)c1cc(C)[nH]n1>>CCOC(=O)c1cc(C)n(CC[C@@H]2CN(C(=O)OCc3ccccc3)CCN2C(=O)OC(C)(C)C)n1 -US20040242569A1,1,C=CCBr.C=CCN(CC=C)CCC(c1ccccc1)c1cc(C)ccc1O>>C=CC[N+](CC=C)(CC=C)CCC(c1ccccc1)c1cc(C)ccc1O -US20110172097A1,7,CC(CCc1ccccc1F)CC(C(=O)C(C)(C)C)n1cncn1>>CC(CCc1ccccc1F)CC(C(O)C(C)(C)C)n1cncn1 -US20100227870A1,1,N#Cc1cc(Cl)ccc1F.O=C(CCOc1ccc(F)cc1)N1CCNCC1>>N#Cc1cc(Cl)ccc1N1CCN(C(=O)CCOc2ccc(F)cc2)CC1 -US20140140956A1,8,COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCNC(C)C)c(-c4ccc(SC)cc4)n3)nc2c1.O=S([O-])OO>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCNC(C)C)c(-c4ccc(S(C)=O)cc4)n3)nc2c1 -US05455252,3,CCc1cc(Br)c2ncccc2c1.OB(O)c1ccc(Cl)c(Cl)c1>>CCc1cc(-c2ccc(Cl)c(Cl)c2)c2ncccc2c1 -US20070142371A1,2,CCc1c(-c2cn(-c3cc(C(=O)OC)ccc3C)cn2)cnn1-c1ccccc1.Cc1c(N)cc(C(C)(C)C)cc1NS(C)(=O)=O>>CCc1c(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4C)ccc3C)cn2)cnn1-c1ccccc1 -US06593324B2,1,CI.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>CN1CCN(c2ccc([N+](=O)[O-])cc2)CC1 -US09045475B2,1,COCCOCCBr.NS(=O)(=O)c1ccc(N[C@@H]2CCNC2)c([N+](=O)[O-])c1>>COCCOCCN1CC[C@@H](Nc2ccc(S(N)(=O)=O)cc2[N+](=O)[O-])C1 -US20080015191A1,1,COc1cc(N)cc(OC)c1OC.Clc1cccc(Oc2cncc(Cl)n2)c1>>COc1cc(Nc2cncc(Oc3cccc(Cl)c3)n2)cc(OC)c1OC -US20040209921A1,1,CC(C)(c1ccc(Cl)cc1)c1cccnc1COS(C)(=O)=O.Cc1cnc(CNCCCCN(C(=O)OC(C)(C)C)C2CC2)c(C)c1>>Cc1cnc(CN(CCCCN(C(=O)OC(C)(C)C)C2CC2)Cc2ncccc2C(C)(C)c2ccc(Cl)cc2)c(C)c1 -US04416884,1,CC1CCc2c(Cl)c(F)cc3c(=O)c(C(=O)O)cn1c23.CN1CCNCC1>>CC1CCc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 -US08288419B2,7,CC1(c2cccc(Cn3ccc([N+](=O)[O-])n3)n2)OCCO1>>CC1(c2cccc(Cn3ccc(N)n3)n2)OCCO1 -US20080207897A1,1,C#CCBr.O=C1CNC(=O)N1>>C#CCN1C(=O)CNC1=O -US07872002B2,1,C1COCCN1.O=c1c2c[nH]c3cc(F)c(F)cc3c-2nn1-c1ccsc1>>O=c1c2c[nH]c3cc(N4CCOCC4)c(F)cc3c-2nn1-c1ccsc1 -US20080039437A1,2,CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1C(F)F.NS(=O)(=O)Cc1ccc(F)cc1Cl>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)Cc3ccc(F)cc3Cl)C2)nc1C(F)F -US05451601,2,CN(C)CCCOc1ccccc1CC(=O)O.O[C@H]1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12>>CN(C)CCCOc1ccccc1CC(=O)N1C[C@@H]2[C@@H](O)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1 -US20120283281A1,6,CC(C)(C)OC(=O)NCCCN(CCCCN(CCCN(CCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCN(CCCCN(CCCN(CCCN)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US20040029882A1,8,CCC(O)C1COC(C)(C)N1C(=O)OC(C)(C)C>>CCC(=O)C1COC(C)(C)N1C(=O)OC(C)(C)C -US07569601B2,3,CC1(C)CC(=O)CC(C)(C)C1.O=C(c1ccc(Br)cc1)c1ccc(O)c(Cl)c1>>CC1(C)CC(=C(c2ccc(Br)cc2)c2ccc(O)c(Cl)c2)CC(C)(C)C1 -US20130116288A1,1,CCc1c(F)ccc(C#N)c1Cl.C[C@H](O)[C@@H](N)C(=O)O>>CCc1c(N[C@@H](C(=O)O)[C@H](C)O)ccc(C#N)c1Cl -US05130119,2,CC1(C)OCC(C(O)CN)O1.O=C(O)c1cc(F)ccc1S(=O)(=O)NC(F)(F)F>>CC1(C)OCC(C(O)CNC(=O)c2cc(F)ccc2S(=O)(=O)NC(F)(F)F)O1 -US20060135355A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.N[C@H](c1cccc(OCc2ccccc2)c1)[C@H](N)c1cccc(OCc2ccccc2)c1>>Cc1ccc(S(=O)(=O)N[C@H](c2cccc(OCc3ccccc3)c2)[C@H](N)c2cccc(OCc3ccccc3)c2)cc1 -US20150111885A1,1,O=[N+]([O-])c1cc(F)cc(Br)c1.Oc1ccc(F)cc1F>>O=[N+]([O-])c1cc(Br)cc(Oc2ccc(F)cc2F)c1 -US04421758,1,Fc1ccc(OC[C@H]2CCC[C@H](OC(CCCl)c3ccc(F)cc3)O2)cc1.c1c[nH]cn1>>Fc1ccc(OC[C@H]2CCC[C@H](OC(CCn3ccnc3)c3ccc(F)cc3)O2)cc1 -US20040010009A1,9,Cc1cc(Br)cc(Br)c1.N#C[Cu]>>Cc1cc(Br)cc(C#N)c1 -US08227474B2,2,COc1ccc(CCCCO)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(CCCCOS(=O)(=O)c2ccc(C)cc2)cc1 -US20120220589A1,6,COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCc4ccc(F)cc43)nc2c1>>O=C(O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCc4ccc(F)cc43)nc2c1 -US08933105B2,6,CN(Cc1cn(S(=O)(=O)c2ccco2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C>>CNCc1cn(S(=O)(=O)c2ccco2)c(-c2cccnc2F)c1F -US06569890B2,4,CCOC(=O)C(CC(C)=O)C(=O)c1ccccc1.CS(=O)(=O)c1cccc(N)c1>>CCOC(=O)c1cc(C)n(-c2cccc(S(C)(=O)=O)c2)c1-c1ccccc1 -US08119673B2,6,CC(C)(C)OC(=O)N1OCC[C@H]1C(=O)NCc1cc(Cl)ccc1-n1cnnn1>>O=C(NCc1cc(Cl)ccc1-n1cnnn1)[C@@H]1CCON1 -US04305868,2,CC(C)(C)c1cc(CCC(=O)O)cc(C(C)(C)C)c1O.CCCCCCCCCCCCCCCCCC(=O)NCCCO>>CCCCCCCCCCCCCCCCCC(=O)NCCCOC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 -US04749701,7,O=[N+]([O-])c1cccc(/C=C/c2ccc3ccccc3n2)c1>>Nc1cccc(/C=C/c2ccc3ccccc3n2)c1 -US08044040B2,9,CSc1nc(Cl)c(C=O)c(Cl)n1.NO>>CSc1nc(Cl)c(C=NO)c(Cl)n1 -US07968592B2,1,Cc1cc(C=O)cc(C)c1O.FC(F)(F)c1ccc(CBr)cc1>>Cc1cc(C=O)cc(C)c1OCc1ccc(C(F)(F)F)cc1 -US20110212956A1,2,CC1NCCc2c(-c3cnn(C)c3)cccc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2cccc(-c3cnn(C)c3)c2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US20100261736A1,6,COc1ccc(-c2c(-c3ccccc3)oc3ccnc(NCC(C)(C)COCC(=O)OC(C)(C)C)c23)cc1>>COc1ccc(-c2c(-c3ccccc3)oc3ccnc(NCC(C)(C)COCC(=O)O)c23)cc1 -US20040198982A1,2,CC(C)C[C@H](Nc1conc1-c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1)C(=O)O.N#CCN>>CC(C)C[C@H](Nc1conc1-c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1)C(=O)NCC#N -US08969336B2,6,CCC1(O)CCC(NC(=O)OC(C)(C)C)CC1>>CCC1(O)CCC(N)CC1 -US20090247526A1,7,CCOC(=O)Cc1csc(Nc2cc(Sc3ccccc3)ccn2)n1>>OCCc1csc(Nc2cc(Sc3ccccc3)ccn2)n1 -US08686048B2,3,Nc1ccc(Br)cc1.OB(O)c1cccc(OC(F)(F)F)c1>>Nc1ccc(-c2cccc(OC(F)(F)F)c2)cc1 -US07402700B2,1,Brc1ccccc1.Cc1ccc(N)cc1C>>Cc1ccc(Nc2ccccc2)cc1C -US20090275590A1,6,Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CN(C(=O)OC(C)(C)C)CC2>>Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CNCC2 -US06350749B1,1,Cc1ccnc2c1C(=O)CC(c1ccsc1Br)C2.N=C(N)NN>>Cc1ccnc2c1C(=NNC(=N)N)CC(c1ccsc1Br)C2 -US08658636B2,6,CCOc1cc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(N4CCOCC4)CC3)c(C(=O)OC)c2cc1S(C)(=O)=O>>CCOc1cc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(N4CCOCC4)CC3)c(C(=O)O)c2cc1S(C)(=O)=O -US05612377,1,CCC(C)Br.O=C(NOCc1ccccc1)Nc1ccccc1>>CCC(C)N(OCc1ccccc1)C(=O)Nc1ccccc1 -US20080090818A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc(Br)n4ncnc34)cc2)C(=O)C1>>O=C1CNCCN1c1ccc(Nc2ncc(Br)n3ncnc23)cc1 -US20090209514A1,2,Nc1cccc2c1CC(O)CC2.O=C(Cl)Oc1ccccc1>>O=C(Nc1cccc2c1CC(O)CC2)Oc1ccccc1 -US07189851B2,5,O=Cc1cc(Br)cs1.OCCO>>Brc1csc(C2OCCO2)c1 -US20090062396A1,5,COCCl.Cc1cc(O)c(C(C)(C)C)cc1F>>COCOc1cc(C)c(F)cc1C(C)(C)C -US08334287B2,3,C#Cc1cccc(C)c1.COCCn1ncc(-n2cc(I)nc2C)cc1=O>>COCCn1ncc(-n2cc(C#Cc3cccc(C)c3)nc2C)cc1=O -US06888029B2,1,O=[N+]([O-])c1ccccc1Cl.c1ccc2[nH]ccc2c1>>O=[N+]([O-])c1ccccc1-n1ccc2ccccc21 -US04307094,6,COC(=O)CCn1c(=O)n2n(c1=O)C(C(=O)O)C=CC2>>O=C(O)CCn1c(=O)n2n(c1=O)C(C(=O)O)C=CC2 -US08415381B2,1,Fc1cc(I)c(Cl)cn1.N[C@H]1CC[C@H](N)CC1>>N[C@@H]1CC[C@@H](Nc2cc(I)c(Cl)cn2)CC1 -US08410089B2,2,CC(N)CO.CCc1cnc(N2CCC(Oc3cc(N4CCc5cc(C(=O)O)ccc54)ncn3)CC2)nc1>>CCc1cnc(N2CCC(Oc3cc(N4CCc5cc(C(=O)NC(C)CO)ccc54)ncn3)CC2)nc1 -US20100267709A1,1,CC1CC2(CCC1=O)OCCO2.NCc1ccccc1>>CC1CC2(CCC1=NCc1ccccc1)OCCO2 -US20150045339A1,4,C#CCCN1C(=O)c2ccccc2C1=O.CSc1ncc(C=NO)c(OCc2ccccc2)n1>>CSc1ncc(-c2cc(CCN3C(=O)c4ccccc4C3=O)on2)c(OCc2ccccc2)n1 -US20150148340A1,1,CCOC(=O)c1cn(-c2ccc3c(c2)[nH]c(=O)n3C)c(=O)[nH]c1=O.FC(F)(F)c1cccc(CBr)c1Cl>>CCOC(=O)c1cn(-c2ccc3c(c2)[nH]c(=O)n3C)c(=O)n(Cc2cccc(C(F)(F)F)c2Cl)c1=O -US20070049632A1,1,BrCCc1ccccc1.CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccccc3)c(=O)c12>>CC1(C)[C@@H]2CC[C@@]1(C)c1c2c(=O)n(-c2ccccc2)n1CCc1ccccc1 -US04421550,1,CCI.COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1n[nH]c(SC)n1>>CCn1nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OC)nc1SC -US04902687,7,NC(=O)c1cnccn1>>NC(=O)C1CNCCN1 -US07655671B2,1,CI.O=C1CC[C@@]2(OCc3ccc(Cl)cc3)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5>>C[N@+]1(CC2CC2)CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(OCc2ccc(Cl)cc2)[C@H]1C5 -US07091357B2,7,CCCCC/C=C/CCC=O>>CCCCC/C=C/CCCO -US20050148627A1,1,CCC(CC)CO.CCOC(=O)C1=Cc2ccc(O)cc2OC1C(F)(F)F>>CCOC(=O)C1=Cc2ccc(OCC(CC)CC)cc2OC1C(F)(F)F -US20140249157A1,1,O=C1CCOC1.O=[N+]([O-])c1cnccc1N1CCNCC1>>O=[N+]([O-])c1cnccc1N1CCN(C2CCOC2)CC1 -US04739050,6,CC(=O)CNC1(c2ccc(OC(C)=O)cc2)Sc2ccccc2N(C)C1=O>>CC(=O)CNC1(c2ccc(O)cc2)Sc2ccccc2N(C)C1=O -US04002746,7,C[C@]12CCC3=C(CCc4cc(O)ccc43)C1=CCC2=O>>C[C@]12CCC3=C(CCc4cc(O)ccc43)[C@@H]1CCC2=O -US20040044030A1,2,COc1ccc2c(=O)n(CCN)c(CN(C)C)c(-c3ccccc3)c2c1.CS(=O)(=O)Cl>>COc1ccc2c(=O)n(CCNS(C)(=O)=O)c(CN(C)C)c(-c3ccccc3)c2c1 -US07786109B2,1,CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCNC2=O)CC1.O=C(CCl)N1CCOCC1>>CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(CC(=O)N3CCOCC3)C2=O)CC1 -US20100317657A1,3,Cc1nn(CC(=O)N2CCN(C)CC2)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21.OB(O)c1ccccc1>>Cc1nn(CC(=O)N2CCN(C)CC2)cc1-n1c(=O)n(C)c2cnc3ccc(-c4ccccc4)cc3c21 -US20090042949A1,2,CC(C)(C)c1ccc(-c2ccc3c(c2)cc(C(=O)Cl)n3-c2ccc(OC3CCCC3)cc2)cc1.CCOC(=O)CN>>CCOC(=O)CNC(=O)c1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC2CCCC2)cc1 -US05409928,6,COc1cccc(Cc2ccc(C3OCCO3)cc2)c1>>COc1cccc(Cc2ccc(C=O)cc2)c1 -US05753707,1,CCCCCC[C@@H](O)C/C=C\CCCCCCCC(=O)OCC.CI>>CCCCCCC(CC=CCCCCCCCC(=O)OCC)OC -US20050080271A1,2,CC(C)(C)[C@H](N)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1.O=C=Nc1cc(F)ccc1F>>CC(C)(C)[C@H](NC(=O)Nc1cc(F)ccc1F)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 -US20130178459A1,3,CC(C)(C)OC(=O)NCC(C)(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1F.COc1cc(C)c2[nH]c(=O)c3sccc3c2c1Br>>COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc(C(C)(C)CNC(=O)OC(C)(C)C)c(F)c1 -US20130030012A1,1,N#Cc1cc(C=O)ccc1F.Oc1ccc(F)cc1>>N#Cc1cc(C=O)ccc1Oc1ccc(F)cc1 -US20030199526A1,1,Clc1ccc(-c2nc(Cl)c3ccccc3n2)c(Cl)c1.N#Cc1ccc(NCCN)nc1>>N#Cc1ccc(NCCNc2nc(-c3ccc(Cl)cc3Cl)nc3ccccc23)nc1 -US07160892B2,1,C=CCn1c(N)nc(-c2cccc(F)c2)c(-c2ccc(=O)[nH]c2)c1=O.OB(O)c1ccccc1>>C=CCn1c(N)nc(-c2cccc(F)c2)c(-c2ccc(=O)n(-c3ccccc3)c2)c1=O -US20100137313A1,3,Cc1cc(C)cc(Nc2ncc(Br)c(-n3nc(C(F)(F)F)cc3C)n2)c1.O=C1NS(=O)(=O)c2ccc(B(O)O)cc21>>Cc1cc(C)cc(Nc2ncc(-c3ccc4c(c3)C(=O)NS4(=O)=O)c(-n3nc(C(F)(F)F)cc3C)n2)c1 -US20090105250A1,1,COC(=O)c1cnc(N)s1.Cc1nc(Cl)cc(Cl)n1>>COC(=O)c1cnc(Nc2cc(Cl)nc(C)n2)s1 -US20110183973A1,2,Cc1cccc(C(=O)O)c1.Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12>>Cc1cccc(C(=O)Nc2cc(-c3cccc4[nH]ccc34)cc3[nH]ncc23)c1 -US20100009957A1,6,O=C(OCc1ccccc1)N1CCC[C@H](NC(=O)N2CC[C@@H]3[C@H]2C(=O)N3S(=O)(=O)O)CC1>>O=C(N[C@H]1CCCNCC1)N1CC[C@@H]2[C@H]1C(=O)N2S(=O)(=O)O -US20090099200A1,1,FC(F)(F)c1ccccc1OC1CCN(c2ncc(Br)s2)CC1.O=C1CCCN1>>O=C1CCCN1c1cnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)s1 -US20090074675A1,1,COc1ccc(F)cc1C(C)(C)CC(O)(CN)C(F)(F)F.COc1cccc(-n2ncc3c(Br)cc(C)cc32)c1>>COc1cccc(-n2ncc3c(NCC(O)(CC(C)(C)c4cc(F)ccc4OC)C(F)(F)F)cc(C)cc32)c1 -US20060264424A1,7,CS(=O)(=O)c1ccc(C#CC(O)(c2ccccc2N(CCC(F)(F)F)S(=O)(=O)c2cccc([N+](=O)[O-])c2)C(F)(F)F)cc1>>CS(=O)(=O)c1ccc(C#CC(O)(c2ccccc2N(CCC(F)(F)F)S(=O)(=O)c2cccc(N)c2)C(F)(F)F)cc1 -US04868321,7,O=c1n(CCCF)nnn1-c1cc([N+](=O)[O-])c(Cl)cc1F>>Nc1cc(-n2nnn(CCCF)c2=O)c(F)cc1Cl -US20050222247A1,1,CC(C)(C)OC(=O)NC[C@H]1CCc2cc(I)ccc2O1.CCOC(=O)c1ccccc1O>>CCOC(=O)c1ccccc1Oc1ccc2c(c1)CC[C@H](CNC(=O)OC(C)(C)C)O2 -US05821250,3,CC(C)(C)c1cc(Br)cc2c1OCC2(C)C.CCCC[Sn](CCCC)(CCCC)c1cccs1>>CC(C)(C)c1cc(-c2cccs2)cc2c1OCC2(C)C -US20070249637A1,1,COC(=O)[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C.Oc1nc(-c2ccccn2)nc2ccsc12>>COC(=O)[C@@H]1C[C@@H](Oc2nc(-c3ccccn3)nc3ccsc23)CN1C(=O)OC(C)(C)C -US08163752B2,6,CC(C)(C)OC(=O)CC1C(=O)C=C2NCCC(=O)Cn3cnc1c32>>O=C(O)CC1C(=O)C=C2NCCC(=O)Cn3cnc1c32 -US06225320B1,8,O[C@H]1CCCN[C@H]1c1ccccc1>>O=C1CCCN[C@H]1c1ccccc1 -US20100056524A1,1,C1CN(C2CC2)CCN1.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(N2CCN(C3CC3)CC2)nc1 -US20150258074A1,1,BrCc1ccccc1.CCOC(=O)n1[nH]c(=O)c2cnc(Cl)cc21>>CCOC(=O)n1c2cc(Cl)ncc2c(=O)n1Cc1ccccc1 -US05968819,1,COc1cccc2c(Cl)nc(Cl)nc12.Nc1ccccc1>>COc1cccc2c(Nc3ccccc3)nc(Cl)nc12 -US04351832,1,CI.COc1cc2nc(N3CCN(c4nc5ccccc5[nH]4)CC3)nc(N)c2cc1OC>>COc1cc2nc(N3CCN(c4nc5ccccc5n4C)CC3)nc(N)c2cc1OC -US04021539,1,CCCCCCN.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CCCCCCNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO -US20100120741A1,6,CC(C)(C)OC(=O)Nc1c(Br)ccc(C(F)(F)F)c1F>>Nc1c(Br)ccc(C(F)(F)F)c1F -US20060235050A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC/C=C/CN>>CC(C)(C)OC(=O)NCC=CCN -US07622464B2,2,CCN.CCOC(=O)c1nnc(CNC(=O)OC(C)(C)C)o1>>CCNC(=O)c1nnc(CNC(=O)OC(C)(C)C)o1 -US20110213143A1,7,CC(C)(C)OC(=O)N1CCC/C(=C\c2ncn3c2CCc2ccccc2-3)C1=O>>CC(C)(C)OC(=O)N1CCCC(Cc2ncn3c2CCc2ccccc2-3)C1=O -US20050059713A1,3,COc1ccc(-c2ccc(C(F)(F)F)cc2)cc1C(=O)N[C@H](Cc1ccc(-c2ccc(F)c(Cl)c2)cc1)C(=O)N(C)OC.C[Mg+]>>COc1ccc(-c2ccc(C(F)(F)F)cc2)cc1C(=O)N[C@H](Cc1ccc(-c2ccc(F)c(Cl)c2)cc1)C(C)=O -US20040006141A1,6,CCOC(=O)C(C)(Cc1ccc(OCc2ccccc2)cc1)Oc1ccccc1>>CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccccc1 -US08372874B2,2,CC(=O)Cl.CNCC(C)(C)c1cc(NC(=O)OC(C)(C)C)on1>>CC(=O)N(C)CC(C)(C)c1cc(NC(=O)OC(C)(C)C)on1 -US20130345123A1,2,N[C@H]1CCCCN(c2ccccc2)C1=O.O=C(O)[C@H](CC[C@H](Cc1ccc(F)cc1)C(=O)O)Cc1ccc(F)cc1>>O=C(O)[C@H](CC[C@H](Cc1ccc(F)cc1)C(=O)N[C@H]1CCCCN(c2ccccc2)C1=O)Cc1ccc(F)cc1 -US20050137224A1,6,CC1(NC(=O)OC(C)(C)C)CCN(c2cnccn2)CC1>>CC1(N)CCN(c2cnccn2)CC1 -US07423159B2,1,ClCc1cscn1.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(OCc2cscn2)cc1 -US20090069282A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.Fc1cc(I)ccc1OCCN1CCCC1>>Fc1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCN1CCCC1 -US20120316195A1,3,CC(=O)c1c(F)cncc1-c1cc2cc(C#N)ccc2o1.C[Mg+]>>CC(C)(O)c1c(F)cncc1-c1cc2cc(C#N)ccc2o1 -US05436240,1,CCC=O.NC1Cc2cccc3ncn(c23)C1>>CCCNC1Cc2cccc3ncn(c23)C1 -US20110144354A1,1,BrCCc1ccc2c(c1)CCO2.NC(=O)C(c1ccccc1)(c1ccccc1)[C@@H]1CCNC1>>NC(=O)C(c1ccccc1)(c1ccccc1)[C@@H]1CCN(CCc2ccc3c(c2)CCO3)C1 -US20090156604A1,3,CCCC[Sn](CCCC)(CCCC)c1nccs1.O=Cc1ccc(-c2nc3ncccn3c2Br)cc1>>O=Cc1ccc(-c2nc3ncccn3c2-c2nccs2)cc1 -US07713994B2,7,N#Cc1ccc(I)c(O)c1>>NCc1ccc(I)c(O)c1 -US20150023990A1,2,CC(C)C(=O)Cl.CCCn1c(COCC)nc2c(N)nc3ccc(OCCCCCCN)cc3c21>>CCCn1c(COCC)nc2c(N)nc3ccc(OCCCCCCNC(=O)C(C)C)cc3c21 -US05747621,3,CC(C)(C)c1ccc([Mg+])cc1.O=C1Cc2ccccc2C1>>CC(C)(C)c1ccc(C2(O)Cc3ccccc3C2)cc1 -US20150266881A1,1,N[C@@H]1C[C@H]1c1cccc(C(=O)NC2CCCC2)c1.O=C1CCN(C2CC2)CC1>>O=C(NC1CCCC1)c1cccc([C@@H]2C[C@H]2NC2CCN(C3CC3)CC2)c1 -US20100160369A1,6,CC(C)(C)[Si](C)(C)OCC(=O)COc1cc(Cl)c(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)cc1Cl>>O=C(CO)COc1cc(Cl)c(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)cc1Cl -US04460596,6,CCOC(=O)Cc1nc(-c2ccccc2)oc1-c1ccsc1>>O=C(O)Cc1nc(-c2ccccc2)oc1-c1ccsc1 -US20130109701A1,1,N#Cc1cc(F)c(CBr)cc1F.Oc1ccc(Cl)c(Cl)c1>>N#Cc1cc(F)c(COc2ccc(Cl)c(Cl)c2)cc1F -US20150175530A1,2,COC(=O)[C@@H](NC(=O)c1ccc(C#CC#C[C@@H](O)CCO)cc1)C(C)(C)N.NO>>CC(C)(N)[C@H](NC(=O)c1ccc(C#CC#C[C@@H](O)CCO)cc1)C(=O)NO -US04880809,2,COc1cc(CN2CCNCC2)cc(OC)c1OC.O=C(O)c1ccc2c(c1)C(=O)c1ccccc1-2>>COc1cc(CN2CCN(C(=O)c3ccc4c(c3)C(=O)c3ccccc3-4)CC2)cc(OC)c1OC -US20120115869A1,3,C#CCO.CCC(=O)N(Cc1cccc(I)c1)c1cccc(-c2nnn[nH]2)c1>>CCC(=O)N(Cc1cccc(C#CCO)c1)c1cccc(-c2nnn[nH]2)c1 -US06969730B2,2,CS(=O)(=O)Cl.N#Cc1ccc(-c2ccc3oc(CCO)cc3c2)cc1>>CS(=O)(=O)OCCc1cc2cc(-c3ccc(C#N)cc3)ccc2o1 -US08022057B2,6,COC(=O)c1c(Cl)cc(=O)n2c1CCC2>>O=C(O)c1c(Cl)cc(=O)n2c1CCC2 -US08735384B2,7,COC(=O)c1cccc(C#CC(C)(C)C)c1-c1ccc2nc(N)c(N3CCOCC3)cc2c1>>COC(=O)c1cccc(CCC(C)(C)C)c1-c1ccc2nc(N)c(N3CCOCC3)cc2c1 -US20110002855A1,3,O=C(CN1CCc2c([nH]c3ccc(Br)cc23)C1)N1CCN(C2CCC2)CC1.OB(O)c1cncnc1>>O=C(CN1CCc2c([nH]c3ccc(-c4cncnc4)cc23)C1)N1CCN(C2CCC2)CC1 -US20090029903A1,1,CCCCc1ccc(C#Cc2ccc(CNc3ccc(F)c(C(=O)OC)c3)cc2)cc1.CCOC(=O)C1CC1C=O>>CCCCc1ccc(C#Cc2ccc(CN(CC3CC3C(=O)OCC)c3ccc(F)c(C(=O)OC)c3)cc2)cc1 -US20120264735A1,4,BrCCOCCBr.NCC(F)(F)CO>>OCC(F)(F)CN1CCOCC1 -US20120283254A1,2,CC(C)CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CC(C)CC(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1 -US08901127B2,6,CC(C)(C)OC(=O)NCc1ncc(Nc2ccc(Cl)cc2C(F)(F)F)cc1F>>NCc1ncc(Nc2ccc(Cl)cc2C(F)(F)F)cc1F -US20130331419A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C(c1ccc(Cl)cc1)n1ccc2c(N)cccc21>>COC(=O)C(c1ccc(Cl)cc1)n1ccc2c(NC(=O)OC(C)(C)C)cccc21 -US20130267493A1,1,COc1ccc(-c2cc3c(C(=O)O)n[nH]c3cc2Cl)cc1.Cc1ccc(O)cc1>>COc1ccc(-c2cc3c(C(=O)Oc4ccc(C)cc4)n[nH]c3cc2Cl)cc1 -US04021457,3,C#C.O=C1CCc2c(O)c3c(c(O)c2C1)C(=O)c1ccccc1C3=O>>C#CC1(O)CCc2c(O)c3c(c(O)c2C1)C(=O)c1ccccc1C3=O -US05958934,3,Cc1nc(N)nc(Cl)c1C.OB(O)c1cccc2ccccc12>>Cc1nc(N)nc(-c2cccc3ccccc23)c1C -US07576082B2,9,O=C1Nc2cc(Cl)ccc2C1(O)C1CCCCC1>>O=C1Nc2cc(Cl)ccc2C1C1CCCCC1 -US20090163490A1,6,Clc1cc(Cl)c(OCc2ccccc2)cc1I>>Oc1cc(I)c(Cl)cc1Cl -US04348399,9,CCCCCCCCCCCCCCCCNc1ccc(CC(=O)Cl)cc1.N>>CCCCCCCCCCCCCCCCNc1ccc(CC(N)=O)cc1 -US06169188A,1,CCOC(=O)COc1ccc(O)c(Cl)c1.CI>>CCOC(=O)COc1ccc(OC)c(Cl)c1 -US08288419B2,2,CC(F)(F)CCCCn1ccc(N)n1.Cc1ccc(/C=C/C(=O)O)cc1>>Cc1ccc(/C=C/C(=O)Nc2ccn(CCCCC(C)(F)F)n2)cc1 -US05627191,1,CC(C)(C)C(=O)OCCl.CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2-c2c(O)c(=O)c2=O)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2-c2c(OCOC(=O)C(C)(C)C)c(=O)c2=O)cc1 -US05206259,9,Cc1ccc(Sc2ccc(CBr)cc2)cc1.N>>Cc1ccc(Sc2ccc(CN)cc2)cc1 -US06391874B1,2,CS(=O)(=O)CCN.O=C(O)c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1>>CS(=O)(=O)CCNC(=O)c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1 -US20150231132A1,2,CCOC(=O)CN1CCN(Cc2c3ccccc3cc3ccccc23)CC1.NN>>NNC(=O)CN1CCN(Cc2c3ccccc3cc3ccccc23)CC1 -US07781443B2,1,CCI.CCOC(=O)N1c2ccc(O)nc2[C@@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)N1c2ccc(OCC)nc2[C@@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC -US20130116243A1,6,CC(C#N)N1C(=O)COc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc21>>CC(C#N)N1C(=O)COc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)cc21 -US05726184,1,NCc1ccccc1.O=C1CCCc2ccc(OCc3ccncc3)cc21>>c1ccc(CNC2CCCc3ccc(OCc4ccncc4)cc32)cc1 -US20020004511A1,1,Cc1cc2cc(N)ccc2[nH]1.Cn1c(-c2cc3nccc(Cl)c3s2)cnc1C#N>>Cc1cc2cc(Nc3ccnc4cc(-c5cnc(C#N)n5C)sc34)ccc2[nH]1 -US08450315B2,3,CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C.Clc1nc(N2CCOCC2)c2sc(-c3cnoc3)cc2n1>>c1cc(-c2nc(N3CCOCC3)c3sc(-c4cnoc4)cc3n2)c2cn[nH]c2c1 -US06191130B1,1,Cc1ccnc(Cl)n1.O[C@@H]1CC[C@@H](N2CCNCC2)CC1>>Cc1ccnc(N2CCN([C@@H]3CC[C@@H](O)CC3)CC2)n1 -US03995056,10,COc1c(C)cccc1C(=O)c1ccc(Cl)cc1.O=C1CCC(=O)N1Br>>COc1c(CBr)cccc1C(=O)c1ccc(Cl)cc1 -US06093731,6,C[C@H](c1ccccc1)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1>>C[C@H](c1ccccc1)N(CC(=O)O)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1 -US20060041146A1,3,CC[Mg+].CON(C)C(=O)c1csc(NC(=O)OC(C)(C)C)n1>>CCC(=O)c1csc(NC(=O)OC(C)(C)C)n1 -US07947676B2,1,C1CCNC1.ClCCCOc1n[nH]c2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>Clc1cc(Nc2ncnc3[nH]nc(OCCCN4CCCC4)c23)ccc1OCc1ccccn1 -US20070259965A1,2,CNCCCNC.N#Cc1ccccc1S(=O)(=O)Cl>>CNCCCN(C)S(=O)(=O)c1ccccc1C#N -US06933311B2,2,CC(C(=O)O)c1cccc2cnccc12.NCc1cccc(OC(F)(F)F)c1>>CC(C(=O)NCc1cccc(OC(F)(F)F)c1)c1cccc2cnccc12 -US20070219186A1,7,CC(=O)c1ccccc1-c1cnn2c(-c3cccc(NC(=O)c4cccc(C(F)(F)F)c4)c3)ccnc12>>CC(O)c1ccccc1-c1cnn2c(-c3cccc(NC(=O)c4cccc(C(F)(F)F)c4)c3)ccnc12 -US07820693B2,1,C1COCCN1.CS(=O)(=O)OCC1CN(c2ccc3cc(-c4ccccc4C(F)(F)F)[nH]c(=O)c3c2)C(=O)O1>>O=C1OC(CN2CCOCC2)CN1c1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1 -US05081287,1,BrCc1ccccc1.OCCCCCCCCCCC=C(F)F>>FC(F)=CCCCCCCCCCCOCc1ccccc1 -US20100322855A1,1,NCCO.O=Cc1ccccc1>>OCC/N=C/c1ccccc1 -US20120029023A1,7,O=[N+]([O-])/C=C/c1ccc(Br)cc1>>O=[N+]([O-])CCc1ccc(Br)cc1 -US20080176926A1,2,CCc1sc(C(=O)CCc2cc(C)c(CCCO)c(C)c2)c2c1CC(C)(C)CC2.CS(=O)(=O)Cl>>CCc1sc(C(=O)CCc2cc(C)c(CCCOS(C)(=O)=O)c(C)c2)c2c1CC(C)(C)CC2 -US06924292B2,1,C=C(C)CCl.COc1cc(C=O)ccc1O>>C=C(C)COc1ccc(C=O)cc1OC -US08815891B2,6,COc1ccc2[nH]c(=O)c3cccnc3c2c1>>O=c1[nH]c2ccc(O)cc2c2ncccc12 -US04182776,1,O=C(O)CCCCCCCCCCBr.Oc1ccccc1>>O=C(O)CCCCCCCCCCOc1ccccc1 -US08188139B2,3,CC(C)(C)OC(=O)N1Cc2ccc(I)cc2C1.CCCC[Sn](CCCC)(CCCC)C1=CCOCC1>>CC(C)(C)OC(=O)N1Cc2ccc(C3=CCOCC3)cc2C1 -US05310743,1,N[C@H]1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccccc2)C1.O=Cc1ccnc2ccccc12>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](NCc2ccnc3ccccc23)C[C@H]1Cc1ccccc1 -US20090023709A1,1,CNCCc1ccccc1.O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl>>CN(CCc1ccccc1)c1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccccc1 -US20140057920A1,2,CC[C@H](C)n1cc(C(=O)O)c(=O)c(Br)c1C.CS(=O)(=O)c1ccc(CN)nc1>>CC[C@H](C)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cn2)c(=O)c(Br)c1C -US20050054662A1,1,CC(C)(C)C(=O)OCCl.CN(C)[C@@H]1CCN(c2cc(O)c3c(=O)[nH]cnc3c2)C1>>CN(C)[C@@H]1CCN(c2cc(O)c3c(=O)n(COC(=O)C(C)(C)C)cnc3c2)C1 -US20040176471A1,6,COc1ccc(OC)c(C(=O)C=Cc2ccc(OC3CCCCO3)cc2)c1>>COc1ccc(OC)c(C(=O)C=Cc2ccc(O)cc2)c1 -US08575153B2,9,[N-]=[N+]=NCC1CCCN1Cc1ccccc1>>NCC1CCCN1Cc1ccccc1 -US20060264460A1,1,N#Cc1ccc(C=O)cc1.N#Cc1cnc2c(C(F)(F)F)cc(N)cc2c1Nc1ccc(F)c(Cl)c1>>N#Cc1ccc(CNc2cc(C(F)(F)F)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)cc1 -US06043265,2,CC(C)(C)CC(=O)Cl.CNCc1cc(-c2ncco2)ccc1-c1ccccc1S(=O)(=O)Nc1noc(C)c1C>>Cc1onc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN(C)C(=O)CC(C)(C)C)c1C -US20110136762A1,3,COc1cc(OC)cc(-c2c(Cl)nnc(C)c2-c2ccccc2)c1.C[Sn](C)(C)c1ccccn1>>COc1cc(OC)cc(-c2c(-c3ccccn3)nnc(C)c2-c2ccccc2)c1 -US20150246922A1,3,N#Cc1cc(Br)c2c(c1)cc1n2CCNC1=O.OCc1ccc(B(O)O)cc1>>N#Cc1cc(-c2ccc(CO)cc2)c2c(c1)cc1n2CCNC1=O -US20050203104A1,3,CC(=O)c1ccc2c(c1)CC(=O)N2C(C)=O.CCCCCCCC(=O)O>>CCCCCCCC(O)=C1C(=O)N(C(C)=O)c2ccc(C(C)=O)cc21 -US20150018369A1,1,CCCI.c1ccc2c(c1)[nH]c1ccccc12>>CCCn1c2ccccc2c2ccccc21 -US20080188531A1,2,CC(C)(C)OC(=O)NCCC(=O)O.CC(C)(N)CO>>CC(C)(CO)NC(=O)CCNC(=O)OC(C)(C)C -US20150175572A1,10,COC(=O)c1cc(OC(C)C)cc(C(=O)OC)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1cc(OC(C)C)cc(C(=O)OC)c1CBr -US20080064715A1,7,CCOC(=O)c1cc2cc(Cl)ncc2[nH]1>>OCc1cc2cc(Cl)ncc2[nH]1 -US07989438B2,6,COC(CN(C)S(=O)(=O)NC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(COCCN(C)Cc1ccccc1)COc1ccccc1-3)OC>>CNCCOCC1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)N(C)CC(OC)OC)cc3n2C1 -US20120214767A1,1,O=C(O)C1CNC1.O=Cc1ccc2c(c1)CCc1c-2noc1CCC1(c2ccc(F)cc2)CCCCC1>>O=C(O)C1CN(Cc2ccc3c(c2)CCc2c-3noc2CCC2(c3ccc(F)cc3)CCCCC2)C1 -US07045528B2,1,CN(C)C(=O)c1cc2nccc(Cl)c2s1.CNC(=O)c1c(C)n(C)c2cc(O)ccc12>>CNC(=O)c1c(C)n(C)c2cc(Oc3ccnc4cc(C(=O)N(C)C)sc34)ccc12 -US05451686,2,CCCCCCCCCCCC(=O)Cl.Cc1oc([Si](C)(C)C)c(-c2ccccc2)c1CO>>CCCCCCCCCCCC(=O)OCc1c(C)oc([Si](C)(C)C)c1-c1ccccc1 -US20090215759A1,1,COc1cc(N)ccc1-n1cnc(C)n1.Cc1cc(Cc2ccccc2)nc(Cl)n1>>COc1cc(Nc2nc(C)cc(Cc3ccccc3)n2)ccc1-n1cnc(C)n1 -US05962473,2,CCC(=O)O.CN1CCC(c2c[nH]c3ccc(N)cc23)CC1>>CCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2c1 -US08314117B2,3,CC(C)(C)OC(=O)N[C@@H]1c2cccnc2C(=O)CC[C@H]1c1cccc(F)c1F.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)/C=C1\CC[C@@H](c2cccc(F)c2F)[C@H](NC(=O)OC(C)(C)C)c2cccnc21 -US20080015222A1,2,COc1cc(N)cc(OCCN2CCCC2=O)c1.O=C(O)Cn1cnc2cccc([N+](=O)[O-])c21>>COc1cc(NC(=O)Cn2cnc3cccc([N+](=O)[O-])c32)cc(OCCN2CCCC2=O)c1 -US20080275022A1,1,CCN1CCNCC1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1c(C)nc2ccc(Br)cc2c1=O>>CCN1CCN(c2ccc3nc(C)n(-c4cc(NC(=O)c5cccc(C(F)(F)F)c5)ccc4C)c(=O)c3c2)CC1 -US08658636B2,1,C1CCN(C2CCNCC2)C1.COC(=O)c1c(CBr)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc12>>COC(=O)c1c(CN2CCC(N3CCCC3)CC2)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc12 -US20140243308A1,2,Cn1ccc(S(=O)(=O)Cl)n1.O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CCNCC5)c4)cnn23)c1>>Cn1ccc(S(=O)(=O)N2CCC(n3cc(-c4cnn5c(-c6cccc(NC(=O)NCC(F)(F)F)c6)cnc5c4)cn3)CC2)n1 -US20090306062A1,1,COCCCN1CCOc2ccc(CO[C@@H]3CC[C@@H](CC(C)(C)C(=O)CCl)N(S(=O)(=O)c4ccc(C)cc4)C3)cc21.NC1CCOCC1>>COCCCN1CCOc2ccc(CO[C@@H]3CC[C@@H](CC(C)(C)C(=O)CNC4CCOCC4)N(S(=O)(=O)c4ccc(C)cc4)C3)cc21 -US08501746B2,1,BrCc1nc2ccccc2s1.Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1ccccc1>>Cc1nc(-n2ccc(OCc3nc4ccccc4s3)cc2=O)sc1C(=O)NCc1ccccc1 -US20090227560A1,2,CC(C)(C)OC(=O)N[C@H](Cc1cccnc1)C(=O)O.CCOC(=O)CNCc1ccccc1>>CCOC(=O)CN(Cc1ccccc1)C(=O)[C@@H](Cc1cccnc1)NC(=O)OC(C)(C)C -US04946855,2,COc1ccc(-c2nc(C)c(C(=O)O)s2)cc1.Nc1nnn[nH]1>>COc1ccc(-c2nc(C)c(C(=O)Nc3nnn[nH]3)s2)cc1 -US20150025075A1,9,COC(=O)C1CC(C#N)(c2ccc(Cl)nc2)CCC1=O>>N#CC1(c2ccc(Cl)nc2)CCC(=O)CC1 -US20050090559A1,1,COc1ccc(F)cc1C(C)(C)CC(O)(C=O)C(F)(F)F.Cc1ncc2c(N)ccc(F)c2n1>>COc1ccc(F)cc1C(C)(C)CC(O)(C=Nc1ccc(F)c2nc(C)ncc12)C(F)(F)F -US05192766,2,COc1cc(C(=O)N2CCNCC2)cc(OC)c1OC.O=C(O)/C=C(\c1ccccc1)c1ccncc1>>COc1cc(C(=O)N2CCN(C(=O)/C=C(\c3ccccc3)c3ccncc3)CC2)cc(OC)c1OC -US08269008B2,9,CCOC(=O)c1nc(I)c2c(-c3ccc(F)cc3)noc2c1O.N#C[Cu]>>CCOC(=O)c1nc(C#N)c2c(-c3ccc(F)cc3)noc2c1O -US07790720B2,7,CC1CCCN1CCCOc1ccc(-c2nc(CC(=O)N3CCCC3)co2)cc1>>CC1CCCN1CCCOc1ccc(-c2nc(CCN3CCCC3)co2)cc1 -US20120035237A1,1,BrCC1CC1.OCc1ccccc1O>>OCc1ccccc1OCC1CC1 -US20140329797A1,6,CC(C)[Si](OCC1(c2cccc(Cn3nc(-c4nc(-c5ccc(OC(F)(F)F)cc5)no4)ccc3=O)c2)CC1)(C(C)C)C(C)C>>O=c1ccc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1cccc(C2(CO)CC2)c1 -US20150191492A1,2,C=CC[C@H]1CNC[C@@]1(N=[N+]=[N-])C(=O)OCC(=O)c1ccccc1.CC(C)(C)OC(=O)N1Cc2cc(Cl)ccc2CC1C(=O)O>>C=CC[C@H]1CN(C(=O)C2Cc3ccc(Cl)cc3CN2C(=O)OC(C)(C)C)C[C@@]1(N=[N+]=[N-])C(=O)OCC(=O)c1ccccc1 -US20080161289A1,2,C1CC(N2CCc3nc(C4CCNCC4)sc3CC2)C1.O=C(O)c1csnn1>>O=C(c1csnn1)N1CCC(c2nc3c(s2)CCN(C2CCC2)CC3)CC1 -US20090258851A1,9,BrC(Br)(Br)Br.CC(C)C(C)(c1ccc(-c2cc(CO)no2)cc1)c1ccc(OCc2ccccn2)cn1>>CC(C)C(C)(c1ccc(-c2cc(CBr)no2)cc1)c1ccc(OCc2ccccn2)cn1 -US20040254156A1,2,CN[C@H](CN1CC[C@H](O)C1)c1ccccc1.CS(=O)(=O)NCc1ccc(CC(=O)O)cc1>>CN(C(=O)Cc1ccc(CNS(C)(=O)=O)cc1)[C@H](CN1CC[C@H](O)C1)c1ccccc1 -US05654445,2,CCOC(=O)C[C@@H](NC(=O)OCc1ccccc1)C(C)C.CN>>CNC(=O)C[C@@H](NC(=O)OCc1ccccc1)C(C)C -US20080076774A1,1,CCCc1n[nH]c2ncnc(Cl)c12.Cc1ccc(Cl)cc1N1CCNCC1>>CCCc1n[nH]c2ncnc(N3CCN(c4cc(Cl)ccc4C)CC3)c12 -US20100152165A1,7,O=C(O)c1ccc2c(c1)N(c1ccccc1)C(=O)CC2>>O=C1CCc2ccc(CO)cc2N1c1ccccc1 -US20120101086A1,6,Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(C(=O)OC(C)(C)C)C2>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCNC2 -US20110071194A1,5,CC(N)C(Oc1cc2cnn(-c3ccc(F)cc3)c2cc1Cl)c1ccc(F)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(NC(=O)C(F)(F)F)C(Oc1cc2cnn(-c3ccc(F)cc3)c2cc1Cl)c1ccc(F)cc1 -US20090137561A1,7,CC/C=C/[C@@H](CC(=O)OC)c1cccc(O)c1>>CCCC[C@H](CC(=O)OC)c1cccc(O)c1 -US05416212,1,CC(C)c1cccc(C(C)C)c1NC(=O)CS(=O)(=O)CCCl.c1ccc(N2CCNCC2)cc1>>CC(C)c1cccc(C(C)C)c1NC(=O)CS(=O)(=O)CCN1CCN(c2ccccc2)CC1 -US20110313175A1,9,CCCCC(CC)CBr.[C-]#N>>CCCCC(CC)CC#N -US20130324506A1,3,CN1CCC(OC2c3ccccc3CCn3cc(I)nc32)CC1.Cc1ccc(B(O)O)cc1>>Cc1ccc(-c2cn3c(n2)C(OC2CCN(C)CC2)c2ccccc2CC3)cc1 -US06531476B1,2,CCN(CC)C(=O)OCC1CNCCN1.COc1cc(C(=O)Cl)cc(OC)c1OC>>CCN(CC)C(=O)OCC1CN(C(=O)c2cc(OC)c(OC)c(OC)c2)CCN1 -US20130310374A1,3,Cn1c(=O)n(-c2ccc(C(C)(C)C#N)nc2)c2c3cc(Br)ccc3ncc21.OB(O)c1cccnc1>>Cn1c(=O)n(-c2ccc(C(C)(C)C#N)nc2)c2c3cc(-c4cccnc4)ccc3ncc21 -US20140228396A1,3,Cc1ccc2nc(-c3cncc(Br)c3)nn2c1.OB(O)C1CC1>>Cc1ccc2nc(-c3cncc(C4CC4)c3)nn2c1 -US20040014968A1,2,COCS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1.Nc1nccs1>>COCS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1 -US20040248931A1,6,CC(C)(C)OC(=O)N1CCC(c2cc3ccccc3c(=O)[nH]2)CC1CO>>O=c1[nH]c(C2CCNC(CO)C2)cc2ccccc12 -US07947685B2,2,COC(=O)c1nccnc1Nc1ccccc1.Nc1cccc(Cl)c1>>O=C(Nc1cccc(Cl)c1)c1nccnc1Nc1ccccc1 -US08927531B2,7,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C(F)(F)F)c4C=O)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C(F)(F)F)c4CO)ccc21 -US04623728,7,COc1cc(-c2cccnc2)ccc1F>>COc1cc(C2CCCNC2)ccc1F -US20120022123A1,3,CCOC(=O)c1cc(Br)c(-c2cc(F)cc(Cl)c2)s1.N#Cc1cc(B(O)O)ccc1F>>CCOC(=O)c1cc(-c2ccc(F)c(C#N)c2)c(-c2cc(F)cc(Cl)c2)s1 -US20080132481A1,2,O=C(O)c1[nH]c2ccccc2c1Nc1ccncc1.OCCN1CCCCC1>>O=C(OCCN1CCCCC1)c1[nH]c2ccccc2c1Nc1ccncc1 -US20080004262A1,2,COc1cc2c(cc1N)OC(C)(C)[C@](O)(CCc1ccccc1)[C@]2(OC(N)=O)C(C)(C)C.O=S(=O)(Cl)CCl>>COc1cc2c(cc1NS(=O)(=O)CCl)OC(C)(C)[C@](O)(CCc1ccccc1)[C@]2(OC(N)=O)C(C)(C)C -US08431695B2,7,CCOC(=O)c1cc(-c2cccc(OCc3ccccc3)c2)c(C#N)n1N>>N#Cc1c(-c2cccc(OCc3ccccc3)c2)cc(CO)n1N -US08048893B2,6,CC(C)(C)OC(=O)N1CCC(n2cc(-c3ccccc3)c(OCc3ccccc3)n2)C1>>c1ccc(COc2nn(C3CCNC3)cc2-c2ccccc2)cc1 -US20060160840A1,1,CN1CCNC(=O)C1.Nc1ccc(I)cc1>>CN1CCN(c2ccc(N)cc2)C(=O)C1 -US20130237540A1,2,CC(C)OC(=O)Cl.Cn1nccc1-c1cc(N)ccc1OCCN1CCCOCC1>>CC(C)OC(=O)Nc1ccc(OCCN2CCCOCC2)c(-c2ccnn2C)c1 -US20100022529A1,6,COC(=O)c1cccn(-c2ccc(F)cc2)c1=O>>O=C(O)c1cccn(-c2ccc(F)cc2)c1=O -US08063234B2,3,CC(=O)c1ccc(C(F)(F)F)cc1.[Mg+]C1CC1>>CC(O)(c1ccc(C(F)(F)F)cc1)C1CC1 -US20110189167A1,7,C=C(C)c1cncc(N)c1>>CC(C)c1cncc(N)c1 -US20100048544A1,7,COC(=O)C(CN1CCN(C(=O)OC(C)(C)C)CC1)c1c(F)ccc2ccc(OC)nc12>>COc1ccc2ccc(F)c(C(CO)CN3CCN(C(=O)OC(C)(C)C)CC3)c2n1 -US06265413B1,3,C1COCCN1.C=O.CC(=O)c1ccccc1[N+](=O)[O-]>>O=C(CCN1CCOCC1)c1ccccc1[N+](=O)[O-] -US20140087992A1,10,CON(C)C(=O)c1cccc(C)c1[N+](=O)[O-].O=C1CCC(=O)N1Br>>CON(C)C(=O)c1cccc(CBr)c1[N+](=O)[O-] -US20130324526A1,9,CC(=O)c1ccc2nnc(Cc3c(F)cc4ncc(N5CCOCC5)cc4c3F)n2n1.NO>>C/C(=N\O)c1ccc2nnc(Cc3c(F)cc4ncc(N5CCOCC5)cc4c3F)n2n1 -US06992103B2,1,COC(=O)c1cccc(Br)c1.O=C1NCCO1>>COC(=O)c1cccc(N2CCOC2=O)c1 -US04830470,2,CCCCC[C@@H]1CC[C@@H](CCc2ccc(O)cc2)CC1.CC[C@H](C)CCCCCOc1ccc(C(=O)Cl)cc1>>CCCCC[C@@H]1CC[C@@H](CCc2ccc(OC(=O)c3ccc(OCCCCC[C@@H](C)CC)cc3)cc2)CC1 -US08455521B2,7,CNC[C@H](CC1CCCCC1)NC(=O)c1cccc(C(=CCCCOC)c2ccccc2)c1>>CNC[C@H](CC1CCCCC1)NC(=O)c1cccc(C(CCCCOC)c2ccccc2)c1 -US04806145,1,COC(=O)C(C)Br.Cc1nn(-c2cc(O)c(Cl)cc2F)c(=O)n1C(F)F>>COC(=O)C(C)Oc1cc(-n2nc(C)n(C(F)F)c2=O)c(F)cc1Cl -US20080039506A1,6,COC(=O)c1ccc(-c2ccc(NCCN(C[C@H](O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)cc1OC1CCCCC1>>CC(C)(C)OC(=O)N(CCNc1ccc(-c2ccc(C(=O)O)c(OC3CCCCC3)c2)cc1)C[C@H](O)c1cccc(Cl)c1 -US20090227799A1,9,COC(=O)c1nc(Cl)c(N)nc1N>>COC(=O)c1ncc(N)nc1N -US20100210619A1,2,CN(c1cc(C(=O)O)ncn1)C1CCCCC1.COCCNS(=O)(=O)c1ccc(N)cc1>>COCCNS(=O)(=O)c1ccc(NC(=O)c2cc(N(C)C3CCCCC3)ncn2)cc1 -US08012986B2,3,CCCC[Sn](CCCC)(CCCC)c1cccc(-c2cccc(S(=O)(=O)NC(C)(C)C)c2)n1.Cc1cc(-c2ccc(C(F)(F)F)nc2)cc(OS(=O)(=O)C(F)(F)F)n1>>Cc1cc(-c2ccc(C(F)(F)F)nc2)cc(-c2cccc(-c3cccc(S(=O)(=O)NC(C)(C)C)c3)n2)n1 -US05962690,1,CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(F)c2Cl)c1O.Cc1cc(C)[nH]n1>>CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(-n3nc(C)cc3C)c2Cl)c1O -US07687452B2,2,CC1(C)CCCC2(C1)CC2(C)C(=O)O.CCOC(=O)CO>>CCOC(=O)COC(=O)C1(C)CC12CCCC(C)(C)C2 -US20100305111A1,2,COCCc1noc(C2CNCC(c3ccc(CC(F)F)cc3)C2)n1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COCCc1noc(C2CC(c3ccc(CC(F)F)cc3)CN(C(=O)Oc3ccc([N+](=O)[O-])cc3)C2)n1 -US20110207771A1,7,C/C(=C\c1ccc(Br)cc1Cl)[N+](=O)[O-]>>CC(Cc1ccc(Br)cc1Cl)[N+](=O)[O-] -US07361659B2,2,Nc1ncc(S(N)(=O)=O)s1.O=C(O)c1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>NS(=O)(=O)c1cnc(NC(=O)c2cnn3c(C(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)s1 -US20130012516A1,6,Cc1c(N2CC3CN(Cc4ccccc4)CC3C2)nn2c(-c3ccnc(N)c3)c(-c3ccc(F)cc3)nc2c1C>>Cc1c(N2CC3CNCC3C2)nn2c(-c3ccnc(N)c3)c(-c3ccc(F)cc3)nc2c1C -US07696209B2,2,CO.O=C(O)[C@H](O)Cc1ccc(O)c(Br)c1>>COC(=O)[C@H](O)Cc1ccc(O)c(Br)c1 -US06797710B2,2,CC(C)OC(=O)N[C@@H](C(=O)O)c1ccccc1.COC(=O)[C@@H]1CCCN1>>COC(=O)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC(C)C)c1ccccc1 -US20110212918A1,6,CCOC(=O)Cc1cc(OC)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2>>CCOC(=O)Cc1cc(O)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2 -US05977105,3,C#CC(O)CCc1cccnc1.CC(=O)c1cccc(-c2ccc(OS(=O)(=O)C(F)(F)F)cc2)c1>>CC(=O)c1cccc(-c2ccc(C#CC(O)CCc3cccnc3)cc2)c1 -US06489324B2,6,CCOC(=O)[C@H]1CN(C(=O)OCc2ccccc2)CCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@@H]1C(=O)O -US04497815,2,COC1CCC(CCN=C=O)CC1OC.O=c1[nH]cc(F)c(=O)[nH]1>>COC1CCC(CCNC(=O)n2cc(F)c(=O)[nH]c2=O)CC1OC -US20110166139A1,1,CNC(=O)c1ccccc1Nc1cc(Cl)ncc1C(F)(F)F.Cc1nn(CCO)cc1N>>CNC(=O)c1ccccc1Nc1cc(Nc2cn(CCO)nc2C)ncc1C(F)(F)F -US20080255124A1,1,COc1ccc(COc2ccc(O)cn2)cc1.N#Cc1ccc(N(CCO)CC(F)(F)F)cc1C(F)(F)F>>COc1ccc(COc2ccc(OCCN(CC(F)(F)F)c3ccc(C#N)c(C(F)(F)F)c3)cn2)cc1 -US20080039506A1,6,COC(=O)c1ccc2cc(-c3ccc(CCN(C[C@H](O)c4cccc(Cl)c4)C(=O)OC(C)(C)C)cc3)ccc2c1>>CC(C)(C)OC(=O)N(CCc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1)C[C@H](O)c1cccc(Cl)c1 -US07217723B2,2,CNCCc1ccc(F)cc1.O=C(O)c1cc(Br)cs1>>CN(CCc1ccc(F)cc1)C(=O)c1cc(Br)cs1 -US04886802,2,CCOC(=O)CC1NCCN(CCc2c[nH]c3ccc(Cl)cc23)C1=O.O=C(Cl)c1ccccc1>>CCOC(=O)CC1C(=O)N(CCc2c[nH]c3ccc(Cl)cc23)CCN1C(=O)c1ccccc1 -US08633173B2,1,CN1CCN(c2ccc(Br)cc2)CC1.CS(=O)(=O)c1ccc(-c2cccc3nc(N)nn23)cc1>>CN1CCN(c2ccc(Nc3nc4cccc(-c5ccc(S(C)(=O)=O)cc5)n4n3)cc2)CC1 -US20130237535A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C1COC2(CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)CN1C1CC1>>CC1(C)OB(c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)OC1(C)C -US05608056,6,C=CCOC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1CCn1ccnc1>>C=CCOC(=O)N1C[C@H](O)C[C@H]1CCn1ccnc1 -US06376491B1,6,CCOC(=O)c1oc2cccc(OCCCNCc3ccccc3)c2c1C>>CCOC(=O)c1oc2cccc(OCCCN)c2c1C -US20120196884A1,2,Cc1ccccc1N=C=O.Nc1ccc(NS(=O)(=O)c2cccc(-c3ccc(F)cc3)c2)cc1>>Cc1ccccc1NC(=O)Nc1ccc(NS(=O)(=O)c2cccc(-c3ccc(F)cc3)c2)cc1 -US08735584B2,1,COc1cccc(N)c1C#N.O=c1[nH]c2nccc(Cl)c2c2ccccc12>>COc1cccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)c1C#N -US08466289B2,7,Cc1c(Nc2ccc(I)cc2F)c([N+](=O)[O-])c2n(c1=O)CCN2Cc1ccccc1>>Cc1c(Nc2ccc(I)cc2F)c(N)c2n(c1=O)CCN2Cc1ccccc1 -US06479518B2,1,CNCCC(=O)OCc1ccccc1.C[C@@H](O[C@H]1CC[C@@H](C=O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CC[C@@H](CN(C)CCC(=O)OCc2ccccc2)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20140296216A1,6,CNc1ncc2c(n1)N(c1cccc(NC(=O)OC(C)(C)C)c1)C(=O)N(C)C2>>CNc1ncc2c(n1)N(c1cccc(N)c1)C(=O)N(C)C2 -US20090192096A1,2,NCCc1ccccc1.O=C(O)c1ccccc1-c1ccccc1CN1C(=O)c2ccccc2C1=O>>O=C(NCCc1ccccc1)c1ccccc1-c1ccccc1CN1C(=O)c2ccccc2C1=O -US04663326,7,Cc1nn(C)c(C(N)=O)c1[N+](=O)[O-]>>Cc1nn(C)c(C(N)=O)c1N -US20150018547A1,6,COC(=O)Cc1coc2c(C)c(OCc3ccc(C)nc3C)cc(C)c12>>Cc1ccc(COc2cc(C)c3c(CC(=O)O)coc3c2C)c(C)n1 -US20140200197A1,7,CC(C)(C)OC(=O)N1C[C@@H](C(F)Cc2ccccc2[N+](=O)[O-])OC[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC(C)(C)OC(=O)N1C[C@@H](C(F)Cc2ccccc2N)OC[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C -US20050182109A1,7,O=C(N1CC=C(c2cnc(-c3ccc4c(c3)CC3CCC(C4)C34CN(CC(F)(F)F)S(=O)(=O)N4)s2)CC1)C(F)(F)F>>O=C(N1CCC(c2cnc(-c3ccc4c(c3)CC3CCC(C4)C34CN(CC(F)(F)F)S(=O)(=O)N4)s2)CC1)C(F)(F)F -US20120059014A1,6,CC(C)(C)OC(=O)N[C@@H]1CN(Cc2ccccc2)C[C@H]1c1cc(F)ccc1F>>CC(C)(C)OC(=O)N[C@@H]1CNC[C@H]1c1cc(F)ccc1F -US06025379,6,COc1ccc(-c2nc3ccccc3n2-c2ccccc2)cc1>>Oc1ccc(-c2nc3ccccc3n2-c2ccccc2)cc1 -US07223765B2,1,Clc1cccc(N2CCNCC2)c1Cl.O=C1CCc2ccccc2N1CCCCBr>>O=C1CCc2ccccc2N1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1 -US20050176689A1,6,CCOC(=O)c1cc(CN(C(C)C)C2CC2)c2c(c1)C(C)(C)CC(C)(C)O2>>CC(C)N(Cc1cc(C(=O)O)cc2c1OC(C)(C)CC2(C)C)C1CC1 -US04493936,8,C=C(CC)CCC(C)O>>C=C(CC)CCC(C)=O -US20140371203A1,6,COCC1CC2CCC(C1)N2c1nc(OC2CC3CC2CN3C(=O)OC(C)(C)C)nc2sc(C(=O)N(C)C)c(-c3ccccc3)c12>>COCC1CC2CCC(C1)N2c1nc(OC2CC3CC2CN3)nc2sc(C(=O)N(C)C)c(-c3ccccc3)c12 -US07326785B2,2,C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](N)C1=O.O=S(=O)(Cl)c1cc2cc(Cl)ccc2o1>>C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](NS(=O)(=O)c2cc3cc(Cl)ccc3o2)C1=O -US04113464,2,CCC(C)NCC1OCCO1.O=C(Cl)CCl>>CCC(C)N(CC1OCCO1)C(=O)CCl -US20130109665A1,2,NN1CCCCC1.O=C(O)c1cnc(C2CC2)c(-c2cccc(Cl)c2)n1>>O=C(NN1CCCCC1)c1cnc(C2CC2)c(-c2cccc(Cl)c2)n1 -US20090181950A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1cnc2c(N3CCNCC3)cccc2c1>>CC(C)(C)OC(=O)N1CCN(c2cccc3cc(I)cnc23)CC1 -US04016165,1,C=CC(Cl)C(C)=O.NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1>>C=CC(Cl)C(C)=NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1 -US20110086843A1,2,CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)Cl)s2)s1.CCN(CC)CCNC>>CCN(CC)CCN(C)S(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)s1 -US05958944,6,C[C@@H](NC(=O)OCc1ccccc1)c1ccc(C(=O)Nc2ccnc3[nH]ccc23)cc1N=[N+]=[N-]>>C[C@@H](N)c1ccc(C(=O)Nc2ccnc3[nH]ccc23)cc1N=[N+]=[N-] -US20040122001A1,6,CCOC(=O)c1cc2scc(Br)c2s1>>O=C(O)c1cc2scc(Br)c2s1 -US08236835B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)CCCCBr>>Cc1nc(NC(=O)CCCCBr)sc1C(=O)NCc1ccccc1 -US20150038528A1,6,CC(C)(C)OC(=O)N[C@@H](CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(=O)O>>N#Cc1nc(C(=O)NCC[C@H](N)C(=O)O)c(O)c2ccc(Oc3ccccc3)cc12 -US20090192213A1,2,CN.O=C(O)c1ccccc1I>>CNC(=O)c1ccccc1I -US07550474B2,3,CCOC(=O)C(F)(F)Br.CS(=O)(=O)c1ccccc1I>>CCOC(=O)C(F)(F)c1ccccc1S(C)(=O)=O -US20090318690A1,6,CN(C)Cc1c(OCc2ccc(F)cc2)ccc2c(CCC3CCN(C(=O)OC(C)(C)C)CC3)noc12>>CN(C)Cc1c(OCc2ccc(F)cc2)ccc2c(CCC3CCNCC3)noc12 -US20090066348A1,5,C=CCN.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCNC(=O)OC(C)(C)C -US08039450B2,9,CCCOc1nc(Cl)ccc1C(N)=O>>CCCOc1nc(Cl)ccc1C#N -US05536737,6,CC(=O)OCC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)NCc1ccccc1>>O=C(CO)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)NCc1ccccc1 -US08680159B2,6,CC1(C)CC2(CCC1NC(=O)OCc1ccccc1)OCCO2>>CC1(C)CC(=O)CCC1NC(=O)OCc1ccccc1 -US20120153268A1,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1-c1cc2ccccc2c2ccccc12>>COC=Cc1ccccc1-c1cc2ccccc2c2ccccc12 -US07468391B2,6,Cc1c(C#C[Si](C)(C)C)cc(C(C)(C)C)c(OC(C)C)c1C=O>>C#Cc1cc(C(C)(C)C)c(OC(C)C)c(C=O)c1C -US06046341,10,COc1cc(C(=O)NC(C)(C)C)ccc1C.O=C1CCC(=O)N1Br>>COc1cc(C(=O)NC(C)(C)C)ccc1CBr -US20110009454A1,2,NCc1cccc(-c2ccccc2)c1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1cccc(-c2ccccc2)c1 -US04590200,7,Cc1c(C(=O)c2cccnc2)sc2cc(Br)ccc12>>Cc1c(Cc2cccnc2)sc2cc(Br)ccc12 -US05051405,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1CCCNC1>>CC(C)(C)OC(=O)N1CCCC(C(=O)O)C1 -US20060084676A1,6,COc1ccc(C2(C)C(=O)Nc3c(Br)cc(Br)cc3C2=O)cc1N>>CC1(c2ccc(O)c(N)c2)C(=O)Nc2c(Br)cc(Br)cc2C1=O -US20060252768A1,1,CC(C)(C)OC(=O)N1CCCC(c2ccc(Br)cc2)C1.CN1CCNCC1>>CN1CCN(c2ccc(C3CCCN(C(=O)OC(C)(C)C)C3)cc2)CC1 -US20090076074A1,2,COc1cc2nccc(Oc3ccc(CC(=O)O)cc3)c2cc1OC.Nc1ccon1>>COc1cc2nccc(Oc3ccc(CC(=O)Nc4ccon4)cc3)c2cc1OC -US20150104384A1,8,CC(C)(C)OC(=O)N1CCC(Sc2ccc(Br)cc2)CC1.OO>>CC(C)(C)OC(=O)N1CCC(S(=O)c2ccc(Br)cc2)CC1 -US07495007B2,7,O=C1CC(c2cccc(Cl)c2)C2(C(=O)Nc3cc(Cl)ccc32)C(c2cc(I)ccc2[N+](=O)[O-])N1>>Nc1ccc(I)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12 -US20070043040A1,3,COC(=O)COc1ccc(Cl)cc1Br.OB(O)c1ccccc1>>COC(=O)COc1ccc(Cl)cc1-c1ccccc1 -US07538102B2,6,CC(C)(C)OC(=O)NS(=O)(=O)N1CCCO1>>NS(=O)(=O)N1CCCO1 -US06426413B1,6,CC(C)(C)OC(=O)CN1C(=O)C(N2C(=O)c3ccccc3C2=O)CCC(=O)N1Cc1ccccc1>>CC(C)(C)OC(=O)CN1C(=O)C(N)CCC(=O)N1Cc1ccccc1 -US07230023B2,8,O=C1OCc2cc(CO)ccc21>>O=Cc1ccc2c(c1)COC2=O -US20150218173A1,3,Brc1cc2c(Nc3ccc4[nH]ncc4c3)ncnc2[nH]1.C=C(C)B1OC(C)(C)C(C)(C)O1>>C=C(C)c1cc2c(Nc3ccc4[nH]ncc4c3)ncnc2[nH]1 -US05051422,7,CC(C)(C)N1CCN(c2ccc(Cl)c(Cl)c2)C(C#N)C1>>CC(C)(C)N1CCN(c2ccc(Cl)c(Cl)c2)C(CN)C1 -US20130289058A1,6,CCc1nc(C)c(C(=O)Nc2ccc(-c3ccc(C45CCC(CC(=O)OC)(CC4)CO5)cc3)cc2)o1>>CCc1nc(C)c(C(=O)Nc2ccc(-c3ccc(C45CCC(CC(=O)O)(CC4)CO5)cc3)cc2)o1 -US07230115B1,2,C=C(F)CN.O=C(O)Cn1ccnc1[N+](=O)[O-]>>C=C(F)CNC(=O)Cn1ccnc1[N+](=O)[O-] -US20120309757A1,2,CCC(N)c1ccccc1.CCOC(=O)c1ccc(-c2ccccc2Cn2c(C)c(C)c3cc(C(=O)O)ccc32)cc1>>CCOC(=O)c1ccc(-c2ccccc2Cn2c(C)c(C)c3cc(C(=O)NC(CC)c4ccccc4)ccc32)cc1 -US20060189601A1,7,CC(C)(C)OC(=O)NCCc1ccncc1>>CC(C)(C)OC(=O)NCCC1CCNCC1 -US20070021443A1,9,NO.O=C1CCOc2c(Br)cc(F)c(F)c21>>ON=C1CCOc2c(Br)cc(F)c(F)c21 -US20120252780A1,3,CC1(C)CCNc2nc(Cl)ccc21.OB(O)c1cccc(C(F)(F)F)c1>>CC1(C)CCNc2nc(-c3cccc(C(F)(F)F)c3)ccc21 -US20030027807A1,2,CCOC(=O)CCN1CCn2nc(C(=O)NC[C@H](NC(=O)OCc3ccccc3)C(=O)OC(C)(C)C)cc2C1=O.N=C(N)N>>CC(C)(C)OC(=O)[C@H](CNC(=O)c1cc2n(n1)CCN(CCC(=O)NC(=N)N)C2=O)NC(=O)OCc1ccccc1 -US20140249133A1,6,COc1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc32)cc1>>COc1cnc(-c2n[nH]c3ccccc23)nc1Nc1ccncc1 -US04144228,6,CS(=O)CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)O>>CS(=O)CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O -US20120258950A1,9,C[C@@H](CO[Si](C)(C)C(C)(C)C)n1ccc2c(Cl)ncnc21>>C[C@@H](CO[Si](C)(C)C(C)(C)C)n1ccc2cncnc21 -US20150119373A1,2,C1COCCN1.CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)Cl)CC[C@]23C)C1(C)C>>CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)N4CCOCC4)CC[C@]23C)C1(C)C -US20110112097A1,1,CC1(C)NC(=O)N(c2ccc(F)c(C(F)(F)F)c2)C1=O.COC(=O)c1ccc(C(=O)c2ccccc2CBr)cc1>>COC(=O)c1ccc(C(=O)c2ccccc2CN2C(=O)N(c3ccc(F)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1 -US05194443,3,CN(CCOc1ccc(C=O)cc1)c1nc2ccccc2o1.O=C1CSC(=O)N1>>CN(CCOc1ccc(C=C2SC(=O)NC2=O)cc1)c1nc2ccccc2o1 -US04439619,9,C=CCC(C(N)=O)(C(=O)OCC)C(F)F>>C=CCC(N)(C(=O)OCC)C(F)F -US20100048568A1,6,COC(=O)C(C)(C)c1cn(NC(=O)c2cnc(-c3ccccn3)nc2C)c2ccc(F)cc12>>Cc1nc(-c2ccccn2)ncc1C(=O)Nn1cc(C(C)(C)C(=O)O)c2cc(F)ccc21 -US20030166929A1,7,Cc1[nH]c(=O)c2c(ccc3nc(Nc4c(Cl)cccc4Cl)n(C)c32)c1CC(=O)N1CCOCC1>>Cc1[nH]c(=O)c2c(ccc3nc(Nc4c(Cl)cccc4Cl)n(C)c32)c1CCN1CCOCC1 -US20100016288A1,2,C1CCNCC1.CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1>>CC(C)(C)OC(=O)N1CCC(C(=O)N2CCCCC2)CC1 -US04212970,5,COc1ccc(C=CC(=O)NN)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(C=CC(=O)NNC(=O)C(F)(F)F)cc1 -US20140275129A1,7,COC(=O)c1cccc([N+](=O)[O-])c1OCc1ccccc1>>COC(=O)c1cccc(N)c1OCc1ccccc1 -US20130023541A1,1,CC(C)OC(=O)c1cccnc1N1CCN(Cc2cccc(Br)c2)CC1.Nc1ccccc1C(F)(F)F>>CC(C)OC(=O)c1cccnc1N1CCN(Cc2cccc(Nc3ccccc3C(F)(F)F)c2)CC1 -US20110053924A1,3,COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@H](CC=O)C[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21.C[Mg+]>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@H](CC(C)O)C[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21 -US06933311B2,2,CCC(C(=O)O)c1cccc2cnccc12.NCc1ccc(Br)cc1>>CCC(C(=O)NCc1ccc(Br)cc1)c1cccc2cnccc12 -US20100113513A1,2,CC(C)(N)CCF.CCC(Oc1ccc2ncc(I)cc2c1)C(=O)O>>CCC(Oc1ccc2ncc(I)cc2c1)C(=O)NC(C)(C)CCF -US20120009151A1,6,CC(C)(C)OC(=O)N1CCC(Nc2nc(Nc3cccc(C(F)(F)F)c3)nc(OCC(F)(F)F)n2)CC1>>FC(F)(F)COc1nc(Nc2cccc(C(F)(F)F)c2)nc(NC2CCNCC2)n1 -US06004959,1,CCCOc1cc(OC)c2c(c1)C(=O)c1cccc(O)c1-2.CCN(CC)CCCl>>CCCOc1cc(OC)c2c(c1)C(=O)c1cccc(OCCN(CC)CC)c1-2 -US08193378B2,1,C1CCNCC1.COC(=O)c1ccc(F)cc1C(F)(F)F>>COC(=O)c1ccc(N2CCCCC2)cc1C(F)(F)F -US08067408B2,3,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cc(Cl)cc(Br)c2)c1.O=Cc1cccc(B(O)O)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cc(Cl)cc(-c3cccc(C=O)c3)c2)c1 -US03953492,1,CC(=N)NS(=O)(=O)c1cc(I)cc(C#N)c1.Clc1ccccc1>>CC(=Nc1ccccc1)NS(=O)(=O)c1cc(I)cc(C#N)c1 -US20140243404A1,7,CCOC(=O)/C=C(\C)CC/C=C(/C)CCC=C(C)C>>CC(C)=CCC/C(C)=C\CC/C(C)=C/CO -US04788204,1,Clc1cc(-c2ccccc2)nc2ccccc12.O=C(O)CCS>>O=C(O)CCSc1cc(-c2ccccc2)nc2ccccc12 -US08034812B2,2,COc1cc(C(=O)O)n(C)n1.Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4C)cn3n2)cc1N>>COc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5C)cn4n3)ccc2C)n(C)n1 -US20030166664A1,7,Cc1ccc([N+](=O)[O-])cc1CC(=O)N1CCC(c2c[nH]c3c(Cl)cccc23)CC1>>Cc1ccc(N)cc1CC(=O)N1CCC(c2c[nH]c3c(Cl)cccc23)CC1 -US20040204427A1,1,CCc1ccc(N2Cc3cnc(Cl)nc3N([C@H]3CC[C@H](O[Si](C)(C)C(C)(C)C)C3)C2=O)cc1.Nc1ccc(F)cc1>>CCc1ccc(N2Cc3cnc(Nc4ccc(F)cc4)nc3N([C@H]3CC[C@H](O[Si](C)(C)C(C)(C)C)C3)C2=O)cc1 -US20130131043A1,1,Clc1ncc2cnn(CC3CCCNC3)c2n1.Cn1cc(N)cn1>>Cn1cc(Nc2ncc3cnn(CC4CCCNC4)c3n2)cn1 -US20150011773A1,4,C#CC[C@@H](C[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CS(=O)(=O)OCCN=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1cn(CCOS(C)(=O)=O)nn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US04908368,1,CCOC(=O)CCC(C)Cl.Sc1nnc(S)s1>>CCOC(=O)CCC(C)Sc1nnc(S)s1 -US20080275029A1,1,N[C@H]1CC[C@H](O)CC1.O=c1[nH]cnc2cc(F)ccc12>>NC1CCC(Oc2ccc3c(=O)[nH]cnc3c2)CC1 -US20140021447A1,3,Cc1cc(Br)ncc1Br.OB(O)c1ccccc1>>Cc1cc(-c2ccccc2)ncc1Br -US06900216B2,3,Brc1cccc2sccc12.CON(C)C(=O)CC1CC1>>O=C(CC1CC1)c1cccc2sccc12 -US04681966,6,CC=C(C(=O)OCC)C(C)CCCC>>CC=C(C(=O)O)C(C)CCCC -US20060128765A1,6,COC(=O)c1ccc(C=C[C@@H]2C[C@H]2C(=O)NCc2ccc(-c3cccc(F)c3C(=O)OC)cc2F)cc1>>COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)[C@@H]2C[C@H]2C=Cc2ccc(C(=O)O)cc2)c(F)c1 -US07078414B2,1,COC(=O)c1cc[nH]c1.Clc1ccnc2ccccc12>>COC(=O)c1ccn(-c2ccnc3ccccc23)c1 -US20100004238A1,1,CN1C(=O)Cc2c(Oc3ccc(N)cc3Cl)cccc21.Cn1c(C#N)cc2ncnc(Cl)c21>>CN1C(=O)Cc2c(Oc3ccc(Nc4ncnc5cc(C#N)n(C)c45)cc3Cl)cccc21 -US07361678B2,1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccc(Cl)cc1C1CCCCC1>>O=[N+]([O-])c1ccc(Oc2ccc(Cl)cc2C2CCCCC2)cc1 -US05736534,1,CC(C)c1ccc2c(c1)NCC2.COc1cc2ncnc(Cl)c2cc1OC>>COc1cc2ncnc(N3CCc4ccc(C(C)C)cc43)c2cc1OC -US20050130251A1,9,Clc1ncnc2ccccc12.NN>>NNc1ncnc2ccccc12 -US20150225449A1,1,CC(=O)N1c2ccccc2NC(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@@H]1C.Cc1ccc2ccccc2c1CCl>>CC(=O)N1c2ccccc2N(Cc2c(C)ccc3ccccc23)C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@@H]1C -US20050136444A1,1,N=C(N)NN.O=Cc1cccc(C(F)(F)F)c1F>>N=C(N)NN=Cc1cccc(C(F)(F)F)c1F -US20030139416A1,1,CNc1cccc(Cl)c1.Clc1ncnc(Cl)n1>>CN(c1cccc(Cl)c1)c1ncnc(Cl)n1 -US06949542B2,2,CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1N.Cc1nccc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)c1C>>Cc1nccc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)ccc3NC(=O)OC(C)(C)C)c2)c1C -US20050222410A1,1,C1CCNC1.CCOC(=O)c1ccc(Br)s1>>CCOC(=O)c1ccc(N2CCCC2)s1 -US20030216410A1,6,CCOC(=O)c1cc(C)c(C=C2C(=O)Nc3ccc(Cl)cc32)[nH]1>>Cc1cc(C(=O)O)[nH]c1C=C1C(=O)Nc2ccc(Cl)cc21 -US06916804B2,1,CC(=O)NCCN.Clc1ccc(-c2nc(Cl)cc(Cl)n2)cc1>>CC(=O)NCCNc1cc(Cl)nc(-c2ccc(Cl)cc2)n1 -US08053440B2,4,COc1cc(N)c(C(N)=O)c(OC)c1.Cc1ccccc1C=O>>COc1cc(OC)c2c(=O)[nH]c(-c3ccccc3C)nc2c1 -US20140155391A1,9,BrC(Br)(Br)Br.COC(=O)c1ccc(C(F)(F)F)c(N(CCO)S(C)(=O)=O)c1>>COC(=O)c1ccc(C(F)(F)F)c(N(CCBr)S(C)(=O)=O)c1 -US05602137,1,Cc1cc(Cl)n2nccc2n1.N#Cc1ccccc1-c1oc2ccc(CN)cc2c1Br>>Cc1cc(NCc2ccc3oc(-c4ccccc4C#N)c(Br)c3c2)n2nccc2n1 -US07666879B2,7,N#Cc1ccc(-c2cnc3cc(-c4ccsc4)ccn23)cc1>>NCc1ccc(-c2cnc3cc(-c4ccsc4)ccn23)cc1 -US04824846,1,Clc1nncc2ccccc12.Oc1ccc(N2CCNCC2)cc1>>Oc1ccc(N2CCN(c3nncc4ccccc34)CC2)cc1 -US20120046269A1,1,Clc1ncnc2[nH]cnc12.NC(=O)c1cccc2c(NCc3cccc(N)c3)ncnc12>>NC(=O)c1cccc2c(NCc3cccc(Nc4ncnc5[nH]cnc45)c3)ncnc12 -US08354444B2,2,CC(C)(C)C[C@@H]1N[C@@H](C(=O)O)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F.COC(=O)c1cc(OC)c(N)cc1F>>COC(=O)c1cc(OC)c(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1F -US20070249637A1,1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O.Clc1cc(-c2ccccn2)nc2ccsc12>>CC(C)(C)OC(=O)N1C[C@H](Oc2cc(-c3ccccn3)nc3ccsc23)C[C@H]1C(=O)O -US20110245271A1,2,CC(N)c1cnccn1.Cc1ccc(-c2cc(C(=O)O)cc(-n3c(C)nnc3C(C)C)c2)cc1>>Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(-n3c(C)nnc3C(C)C)c2)cc1 -US20130217666A1,3,C#C[C@]1(O)CCN(C)C1=O.CNC(=O)c1c(C(N)=O)nn2c1CCOc1ccc(Br)cc1-2>>CNC(=O)c1c(C(N)=O)nn2c1CCOc1ccc(C#C[C@]3(O)CCN(C)C3=O)cc1-2 -US20080171743A1,3,CC(C)(C)OC(=O)Nc1ccc(B(O)O)cc1.C[C@H]1COCCN1c1cc(CS(C)(=O)=O)nc(Cl)n1>>C[C@H]1COCCN1c1cc(CS(C)(=O)=O)nc(-c2ccc(NC(=O)OC(C)(C)C)cc2)n1 -US20080188521A1,1,CCC(O)(c1cn(Cc2ccc3c(-c4ccc(F)cc4)cc(Cl)nc3c2)nn1)C(F)(F)F.NCc1ccccc1>>CC[C@](O)(c1cn(Cc2ccc3c(-c4ccc(F)cc4)cc(NCc4ccccc4)nc3c2)nn1)C(F)(F)F -US20030191309A1,2,COC(=O)CCN(CCc1ccc(OC)cc1)S(=O)(=O)c1ccc(-c2nnn[nH]2)cc1.NO>>COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(-c3nnn[nH]3)cc2)cc1 -US07220868B2,7,CCCCCCCCCCCCCCCCCCOc1ccc([N+](=O)[O-])c(C)c1>>CCCCCCCCCCCCCCCCCCOc1ccc(N)c(C)c1 -US04782147,8,CCS[C@@H]1NC(=O)[C@H]1NC(=O)COc1ccccc1.OO>>CCS(=O)[C@@H]1NC(=O)[C@H]1NC(=O)COc1ccccc1 -US20090264404A1,1,CC(=O)N1CCNCC1.COc1cc(Br)cc(C)c1OCCCN1CCN(c2cccc3sccc23)CC1>>COc1cc(N2CCN(C(C)=O)CC2)cc(C)c1OCCCN1CCN(c2cccc3sccc23)CC1 -US20080275054A1,1,CCN(CC)CCBr.O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)c(Nc2ncnc3[nH]ncc23)c1>>CCN(CC)CCn1ncc2c(Nc3cc(C(=O)Nc4cccc(C(F)(F)F)c4)ccc3Cl)ncnc21 -US20110166152A1,6,COC(=O)CNc1nc2ncc(-c3cn(Cc4cc(Cl)c(Cl)c(Cl)c4)nn3)nc2s1>>O=C(O)CNc1nc2ncc(-c3cn(Cc4cc(Cl)c(Cl)c(Cl)c4)nn3)nc2s1 -US20060241145A1,2,CC(=O)NC(C)C(=O)O.COc1ccc(-n2nnnc2C(F)(F)F)cc1CN[C@H]1CCNC[C@H]1c1ccccc1>>COc1ccc(-n2nnnc2C(F)(F)F)cc1CN[C@H]1CCN(C(=O)C(C)NC(C)=O)C[C@H]1c1ccccc1 -US20050049252A1,6,CCOC(=O)C1=Cc2cc(Cl)ccc2OC1C(F)(F)F>>O=C(O)C1=Cc2cc(Cl)ccc2OC1C(F)(F)F -US20070082880A1,3,C#CCCN1CCN(C)CC1.N#Cc1cnc2sc(I)cc2c1Nc1ccc2[nH]ccc2c1>>CN1CCN(CCC#Cc2cc3c(Nc4ccc5[nH]ccc5c4)c(C#N)cnc3s2)CC1 -US20040209921A1,1,CC(NCCCCNC(=O)OC(C)(C)C)c1nccn1C.Cc1cccnc1C=O>>Cc1cccnc1CN(CCCCNC(=O)OC(C)(C)C)C(C)c1nccn1C -US20130184313A1,3,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc([Sn](C)(C)C)c1.COC(=O)C=Cc1cc(F)cc(I)c1>>COC(=O)C=Cc1cc(F)cc(-c2cncc(OC[C@@H]3CCN3C(=O)OC(C)(C)C)c2)c1 -US04634704,1,Cn1cnc([N+](=O)[O-])c1Cl.NCCN1CCC(Nc2nc3cccnc3n2Cc2ccc(F)cc2)CC1>>Cn1cnc([N+](=O)[O-])c1NCCN1CCC(Nc2nc3cccnc3n2Cc2ccc(F)cc2)CC1 -US07910613B2,2,CCc1noc(-c2sc(N)nc2-c2ccccc2)n1.O=C(Cl)Cc1ccccc1>>CCc1noc(-c2sc(NC(=O)Cc3ccccc3)nc2-c2ccccc2)n1 -US06759547B1,6,CCCOc1cc2c(cc1/C(CC)=C(F)\C=C\C(C)=C(/F)C(=O)OCC)C(C)(C)CCC2(C)C>>CCCOc1cc2c(cc1/C(CC)=C(F)\C=C\C(C)=C(/F)C(=O)O)C(C)(C)CCC2(C)C -US07547809B2,3,O=C1c2ccccc2C(=O)c2cc(Cl)ccc21.OB(O)c1ccccc1-c1ccccc1>>O=C1c2ccccc2C(=O)c2cc(-c3ccccc3-c3ccccc3)ccc21 -US05997843,1,CC(C)=CCBr.O=[N+]([O-])c1ncc[nH]1>>CC(C)=CCn1ccnc1[N+](=O)[O-] -US06569890B2,4,CCOC(=O)C(CC(C)=O)C(=O)c1ccccc1.Nc1cccc(I)c1>>CCOC(=O)c1cc(C)n(-c2cccc(I)c2)c1-c1ccccc1 -US20150166549A1,1,Nc1ncnc2[nH]nc(I)c12.O=c1oc(CBr)c(-c2ccccc2)c2ccccc12>>Nc1ncnc2c1c(I)nn2Cc1oc(=O)c2ccccc2c1-c1ccccc1 -US04735940,8,CN(C)CCOC(=O)c1cc(-c2ccccc2)c(=O)n2c1-c1sccc1SCC2.O=C(OO)c1cccc(Cl)c1>>CN(C)CCOC(=O)c1cc(-c2ccccc2)c(=O)n2c1-c1sccc1S(=O)CC2 -US20090048203A1,2,O=C(Cl)c1ccccc1.O=C1C=CC(O)C1>>O=C1C=CC(OC(=O)c2ccccc2)C1 -US20140134235A1,7,CCOC(=O)c1cnc2ccccc2c1N(CC1CC1)CC1CC1>>OCc1cnc2ccccc2c1N(CC1CC1)CC1CC1 -US06579870B2,6,CC(=O)Nc1cc(N2CCCN(C(=O)OC(C)(C)C)CC2)ccc1S(=O)(=O)c1cccc(F)c1>>CC(=O)Nc1cc(N2CCCNCC2)ccc1S(=O)(=O)c1cccc(F)c1 -US20020002190A1,6,COC(=O)c1ccc(NC(=O)C(CC2CCCC2)c2ccc(-c3cccc4ccccc34)cc2)nc1>>O=C(O)c1ccc(NC(=O)C(CC2CCCC2)c2ccc(-c3cccc4ccccc34)cc2)nc1 -US20070043029A1,6,COC(=O)c1ccc(C(=O)OCc2ccccc2)cc1F>>COC(=O)c1ccc(C(=O)O)cc1F -US20150038481A1,2,Nc1ccc(S(=O)(=O)N2CCOCC2)cc1.O=C(Cl)c1cnc(Cl)nc1Cl>>O=C(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1cnc(Cl)nc1Cl -US20140322355A1,2,CCOC(=O)C(=O)OCC.NN>>CCOC(=O)C(=O)NN -US20130029980A1,1,CC(C)c1ccc(N)c([N+](=O)[O-])c1.CC(CBr)Cc1ccc(Cl)cc1>>CC(CNc1ccc(C(C)C)cc1[N+](=O)[O-])Cc1ccc(Cl)cc1 -US20020164616A1,1,ClCCBr.O=[N+]([O-])c1ccccc1O>>O=[N+]([O-])c1ccccc1OCCCl -US07678825B2,2,CCOc1cc([C@@H](CC(=O)N(C)C)N2Cc3cccc(N)c3C2=O)ccc1OC.O=C(Cl)C1CC1>>CCOc1cc([C@@H](CC(=O)N(C)C)N2Cc3cccc(NC(=O)C4CC4)c3C2=O)ccc1OC -US20080255152A1,7,N#Cc1ccc(Oc2ccc(C(N)=O)cc2)nc1>>NCc1ccc(Oc2ccc(C(N)=O)cc2)nc1 -US04939140,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1OC(=O)c2cc(Cl)c(Cl)cc21>>CCOC(=O)C=C1OC(=O)c2cc(Cl)c(Cl)cc21 -US20080177095A1,6,CCCCCC1CCc2c(I)c(OCOC)c(F)c(F)c2O1>>CCCCCC1CCc2c(I)c(O)c(F)c(F)c2O1 -US20030153752A1,7,Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1C=CC(O)C1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCC(O)C1 -US20110053949A1,2,Cc1cnc(N)cn1.O=C(Cl)Oc1ccccc1>>Cc1cnc(NC(=O)Oc2ccccc2)cn1 -US08691810B2,2,CCN=C=O.Cn1cc(-c2cc3c(-c4cnc(C5(N)CCC5)s4)c(Cl)cnc3[nH]2)cn1>>CCNC(=O)NC1(c2ncc(-c3c(Cl)cnc4[nH]c(-c5cnn(C)c5)cc34)s2)CCC1 -US20120184553A1,1,COC(=O)c1cc(I)ccc1O.Fc1ccc(CBr)cc1>>COC(=O)c1cc(I)ccc1OCc1ccc(F)cc1 -US06818718B2,2,C=C(C)C(=O)Cl.NCCN>>C=C(C)C(=O)NCCN -US05565479,4,NC(=S)Cc1c[nH]cn1.O=C1c2ccc3ccccc3c2CCC1Br>>c1ccc2c3c(ccc2c1)-c1nc(Cc2c[nH]cn2)sc1CC3 -US08022205B2,1,CC(C)(C)NC(=O)c1cc(Cl)ccn1.COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4)cn2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccnc(C(=O)NC(C)(C)C)c3)cn2)cc1 -US07417066B2,2,CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3sc(C(=O)O)c(-c4ccccc4)c3c2)cc1.NCCN1CCOCC1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3sc(C(=O)NCCN4CCOCC4)c(-c4ccccc4)c3c2)cc1 -US04921939,2,CC(C)(C)OC(=O)CN.N#Cc1ccc(N=C=S)cc1>>CC(C)(C)OC(=O)CNC(=S)Nc1ccc(C#N)cc1 -US20060223801A1,9,Cc1[nH]c(C(=O)NC2CCN(c3cc(C(N)=O)nc(Cl)n3)CC2)c(Cl)c1Cl>>Cc1[nH]c(C(=O)NC2CCN(c3cc(C#N)nc(Cl)n3)CC2)c(Cl)c1Cl -US08338605B2,1,COc1cccc(-c2ccc(C)cc2N)c1.Cc1ccc2c(Cl)ccnc2n1>>COc1cccc(-c2ccc(C)cc2Nc2ccnc3nc(C)ccc23)c1 -US20110178064A1,3,C[C@H]1CN(c2ncc(Br)cc2C=O)C[C@@H](C)O1.OB(O)c1cccnc1>>C[C@H]1CN(c2ncc(-c3cccnc3)cc2C=O)C[C@@H](C)O1 -US20090192162A1,6,CC#CCOc1cc(C#CCN2CCOCC2)cc(Sc2ccc(OCC(=O)OCC)c(C)c2)c1>>CC#CCOc1cc(C#CCN2CCOCC2)cc(Sc2ccc(OCC(=O)O)c(C)c2)c1 -US20110294810A1,7,N#Cc1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1>>NCc1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1 -US09120749B2,3,CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C.O=C(c1cnc2ccc(Br)cc2c1N[C@@H]1CC[C@@H](CN2CCC(O)C2)CC1)C1CC1>>O=C(c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1N[C@@H]1CC[C@@H](CN2CCC(O)C2)CC1)C1CC1 -US20080074033A1,3,C[Si](C)(C)c1ccc(B(O)O)cc1.Cc1ccc(Br)nc1>>Cc1ccc(-c2ccc([Si](C)(C)C)cc2)nc1 -US20120252796A1,6,COC(=O)C1(C)OCC(Cc2nc(-c3ccccc3)oc2C)CO1>>Cc1oc(-c2ccccc2)nc1CC1COC(C)(C(=O)O)OC1 -US20110118283A1,6,CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2F)C1(C#N)c1ncc(Cl)cc1F>>CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ncc(Cl)cc1F -US20100249123A1,7,CC(C)(C#N)c1ccc([N+](=O)[O-])cc1F>>CC(C)(CN)c1ccc([N+](=O)[O-])cc1F -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(O)c3ccccc3)CC2)c1.CCOc1ccccc1O>>CCOc1ccccc1OC(CCCCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)c1ccccc1 -US04075165,1,C=O.CCC1(C)CC(OCc2ccccc2)C(C)C(C)(CC)N1>>CCC1(C)CC(OCc2ccccc2)C(C)C(C)(CC)N1C -US20100185019A1,3,COc1ccc([Mg+])cc1.Fc1cc(F)cc(Br)c1>>COc1ccc(-c2cc(F)cc(F)c2)cc1 -US08063061B2,6,COc1ccc(-c2cc3c4cc(-c5ccn[nH]5)ccc4n(C)c3n(C)c2=O)c(Cl)c1>>Cn1c(=O)c(-c2ccc(O)cc2Cl)cc2c3cc(-c4ccn[nH]4)ccc3n(C)c21 -US07033765B1,2,Cc1cccc(C)c1N.O=C(O)CBr>>Cc1cccc(C)c1NC(=O)CBr -US20050043309A1,7,O=C1CCc2ccc(C=CCCCN3CCN(c4cccc5c4CCCC5)CC3)nc2N1>>O=C1CCc2ccc(CCCCCN3CCN(c4cccc5c4CCCC5)CC3)nc2N1 -US05070196,9,CCCCCC(=O)CCCCC.NO>>CCCCCC(CCCCC)=NO -US08288403B2,1,Clc1cccc(CBr)c1.Nc1cc[nH]n1>>Nc1ccn(Cc2cccc(Cl)c2)n1 -US20110112103A1,1,CCOC(=O)C(C(=O)OCC)c1ccc(Br)cc1.CNc1ccccc1>>CCOC(=O)C(C(=O)OCC)c1ccc(N(C)c2ccccc2)cc1 -US05120348,2,CC(Br)C(=O)Cl.OCC1CCCO1>>CC(Br)C(=O)OCC1CCCO1 -US20150164876A1,3,O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(Br)c1.O=[N+]([O-])c1ccccc1B(O)O>>O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(-c2ccccc2[N+](=O)[O-])c1 -US07994203B2,3,C=O.CCCNCCC.CCc1oc2cc(C)nn2c1-c1ccc(Cl)cc1Cl>>CCCN(CCC)Cc1c(C)nn2c(-c3ccc(Cl)cc3Cl)c(CC)oc12 -US20040077877A1,2,CC(C)(N)c1ccccc1.COC(=O)c1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1>>CC(C)(NC(=O)c1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1)c1ccccc1 -US08349880B2,9,Nc1cc(F)c(-n2cnc(Cl)c2)c(F)c1>>Nc1cc(F)c(-n2ccnc2)c(F)c1 -US20040248983A1,3,COc1cc(CC(=O)Nc2cccc(I)c2)ccc1OCCNC(=O)OC(C)(C)C.OB(O)c1ccccc1>>COc1cc(CC(=O)Nc2cccc(-c3ccccc3)c2)ccc1OCCNC(=O)OC(C)(C)C -US08063071B2,3,CC1(C)OB(c2cccc(CN)c2)OC1(C)C.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CN)c4)cc23)CC1 -US20110046170A1,1,CCCN.Cc1cc(C(=N)NO)nc(Cl)n1>>CCCNc1nc(C)cc(C(=N)NO)n1 -US20100210642A1,2,NCc1ccncc1.O=S(=O)(Cl)c1ccc(Br)s1>>O=S(=O)(NCc1ccncc1)c1ccc(Br)s1 -US20090062322A1,6,Clc1ccc2c(c1)CC1(CCN(Cc3ccccc3)C1)O2>>Clc1ccc2c(c1)CC1(CCNC1)O2 -US20100120793A1,1,CCOC(=O)C1(CI)CCN(C(=O)c2ccc(F)cc2)C1.Oc1ccc(-c2ccc(Cl)cn2)cc1>>CCOC(=O)C1(COc2ccc(-c3ccc(Cl)cn3)cc2)CCN(C(=O)c2ccc(F)cc2)C1 -US20110294837A1,1,Nc1nccc(Cl)n1.O=C(Nc1ccc(O)cc1)c1ccccc1Nc1ccc(F)cc1>>Nc1nccc(Oc2ccc(NC(=O)c3ccccc3Nc3ccc(F)cc3)cc2)n1 -US20080249137A1,1,CCOc1cc(O)cc(CC(=O)OC)c1.FC(F)(F)c1ccc(-c2cccc(Br)c2)cc1>>CCOc1cc(CC(=O)OC)cc(Oc2cccc(-c3ccc(C(F)(F)F)cc3)c2)c1 -US06177443B1,2,CN(C)CCOc1ccc(C(=O)O)cc1.COc1cc2c(cc1Cl)CCNCC2c1cccc2c1OCC2>>COc1cc2c(cc1Cl)CCN(C(=O)c1ccc(OCCN(C)C)cc1)CC2c1cccc2c1OCC2 -US20130053404A1,3,CC(C)c1nc2c(c(I)c1[C@H](O)c1ccc(C(F)(F)F)cc1)[C@@H](O[Si](C)(C)C(C)(C)C)CC1(CCC1)C2.CC1(C)OB(C2=CCOCC2)OC1(C)C>>CC(C)c1nc2c(c(C3=CCOCC3)c1[C@H](O)c1ccc(C(F)(F)F)cc1)[C@@H](O[Si](C)(C)C(C)(C)C)CC1(CCC1)C2 -US20120172385A1,2,CC(=O)Cl.Nc1c(F)cccc1[N+](=O)[O-]>>CC(=O)Nc1c(F)cccc1[N+](=O)[O-] -US20060035956A1,3,C#CCNC(=O)Cc1ccc2cc[nH]c2c1.FC(F)(F)Oc1ccc(I)cc1>>O=C(Cc1ccc2cc[nH]c2c1)NCC#Cc1ccc(OC(F)(F)F)cc1 -US04770695,1,COC(=O)CBr.O=C1C2=C(CCCC2)C(=O)N1c1cc(O)c(Cl)cc1F>>COC(=O)COc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl -US20110281854A1,1,C[C@@H]1CN[C@@H](c2ccc(F)cc2)CO1.O=C1COc2ccc(Br)nc2N1>>C[C@H]1CN(c2ccc3c(n2)NC(=O)CO3)[C@H](c2ccc(F)cc2)CO1 -US20130040930A1,1,Cc1cnc(N2CCN(C(=O)c3c(F)cc(Br)cc3F)CC2)c(C)c1.O=C1CC[C@H](CO)N1>>Cc1cnc(N2CCN(C(=O)c3c(F)cc(N4C(=O)CC[C@@H]4CO)cc3F)CC2)c(C)c1 -US20120115851A1,2,COC(=O)c1cc(Cl)ccc1N.O=C(Cl)c1cccc(CCl)c1>>COC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(CCl)c1 -US20050020616A1,7,O=C(N1CC2CCC(C1)c1cc([N+](=O)[O-])c(O)cc12)C(F)(F)F>>Nc1cc2c(cc1O)C1CCC2CN(C(=O)C(F)(F)F)C1 -US20080015232A1,1,CCOP(OCC)OCC.COCOc1cc(CI)cc(OCOC)c1CC=C(C)CCC=C(C)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CCOP(=O)(Cc1cc(OCOC)c(CC=C(C)CCC=C(C)CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(OCOC)c1)OCC -US05214148,6,CC1(O[Si](C)(C)C)CN(C(=O)OCc2ccccc2)CCC1=O>>CC1(O)CN(C(=O)OCc2ccccc2)CCC1=O -US20110269738A1,3,CC(C)Cc1ccc(-c2nc(Br)ns2)cc1C#N.CCc1c(C=O)cccc1B1OC(C)(C)C(C)(C)O1>>CCc1c(C=O)cccc1-c1nsc(-c2ccc(CC(C)C)c(C#N)c2)n1 -US20120220603A1,4,C#CCO.O/N=C/c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>OCc1cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)no1 -US08592463B2,1,CC(C)(C)OC(=O)N1CCNCC1.Cn1c(-c2cc(Br)ccc2F)nc2ccccc21>>Cn1c(-c2cc(N3CCN(C(=O)OC(C)(C)C)CC3)ccc2F)nc2ccccc21 -US20100261719A1,2,C[C@@H]1O[C@H](C)CN2c3c(cc(C(=O)O)c(F)c3F)CC3(C(=O)NC(=O)NC3=O)[C@@H]12.NC1CCOC1=O>>C[C@@H]1O[C@H](C)CN2c3c(cc(C(=O)NC4CCOC4=O)c(F)c3F)CC3(C(=O)NC(=O)NC3=O)[C@@H]12 -US05753665,1,CC(Br)c1ccnc2ncnn12.Oc1ccc(F)cc1>>CC(Oc1ccc(F)cc1)c1ccnc2ncnn12 -US05908859,1,BrC1CCCC1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OC2CCCC2)cc1 -US20030055064A1,4,ClCCNCCCl.Nc1c(F)cc(F)cc1F>>Fc1cc(F)c(N2CCNCC2)c(F)c1 -US07943651B2,7,COc1ccc(F)cc1C(C)(C)C[C@@](O)(C(=O)O)C(F)(F)F>>COc1ccc(F)cc1C(C)(C)C[C@@](O)(CO)C(F)(F)F -US08026248B2,1,Cc1cc(Br)c(N)c(Br)c1.N#Cc1ccc(Nc2nccc(Cl)n2)cc1>>Cc1cc(Br)c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)c(Br)c1 -US05556854,1,CCOC(=O)C(Cl)c1ccccc1Cl.O=c1[nH]c2c(c(=O)n1Cc1ccccc1)CNCC2>>CCOC(=O)C(c1ccccc1Cl)N1CCc2[nH]c(=O)n(Cc3ccccc3)c(=O)c2C1 -US08084489B2,3,COC(=O)CCNC(=O)c1ccc(C(CCC(F)(F)F)Oc2cc(C)c(I)c(C)c2)s1.OB(O)c1ccc(OC(F)(F)F)cc1>>COC(=O)CCNC(=O)c1ccc(C(CCC(F)(F)F)Oc2cc(C)c(-c3ccc(OC(F)(F)F)cc3)c(C)c2)s1 -US05843942,6,CCN(Cc1ccccc1OCc1ccccc1)c1ccc(C(=O)OC(C)(C)C)c(F)c1>>CCN(Cc1ccccc1OCc1ccccc1)c1ccc(C(=O)O)c(F)c1 -US04127673,2,Nc1ccccc1.S=C(Cl)N(Cc1ccc(Br)cc1)C1CCCC1>>S=C(Nc1ccccc1)N(Cc1ccc(Br)cc1)C1CCCC1 -US05360807,1,CCOC(=O)N1CCC(Nc2nc3ccccc3[nH]2)CC1.Cc1nc(CCl)cs1>>CCOC(=O)N1CCC(Nc2nc3ccccc3n2Cc2csc(C)n2)CC1 -US20120028973A1,3,OB(O)c1ccc(OC(F)(F)F)c(F)c1.OCc1ccc(Br)cn1>>OCc1ccc(-c2ccc(OC(F)(F)F)c(F)c2)cn1 -US20090054435A1,2,CNOC.COc1ccc(O)c(C(=O)O)c1>>COc1ccc(O)c(C(=O)N(C)OC)c1 -US08354444B2,6,CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2cccc(C(=O)OC(C)(C)C)c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2cccc(C(=O)O)c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20030055247A1,3,C#C[Si](C)(C)C.O=S(=O)(Oc1cncc(Cl)c1)C(F)(F)F>>C[Si](C)(C)C#Cc1cncc(Cl)c1 -US20120277265A1,1,COc1ccc2cccnc2c1O.ClCc1ccccc1>>COc1ccc2cccnc2c1OCc1ccccc1 -US06310061B2,2,CCCN.O=C(O)c1ccc([N+](=O)[O-])s1>>CCCNC(=O)c1ccc([N+](=O)[O-])s1 -US07342031B2,1,CSc1nsc(Cl)n1.OCc1ccco1>>CSc1nsc(OCc2ccco2)n1 -US05216022,1,CC(C)(C)[O-].CC(C)(CCl)C(=O)Cl>>CC(C)(C)OC(=O)C(C)(C)CCl -US08575360B2,2,CC(C)(C)OC(=O)NC1(c2ccc(C(=O)NN)cn2)CC1.O=C(O)C1CC1>>CC(C)(C)OC(=O)NC1(c2ccc(C(=O)NNC(=O)C3CC3)cn2)CC1 -US06492522B1,7,CCOC(=O)C(=Cc1ccncc1)C(=O)OCC>>CCOC(=O)C(=CC1CCNCC1)C(=O)OCC -US20140213586A1,1,COc1cccc(N)c1.Cc1ccccc1C=O>>COc1cccc(N=Cc2ccccc2C)c1 -US04063022,1,ClCc1ccc(Cl)c(Cl)c1.O=C1NCCN1>>O=C1NCCN1Cc1ccc(Cl)c(Cl)c1 -US08022203B2,8,C[C@]12CC[C@H](O)CC1NC(=O)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12>>C[C@]12CCC(=O)CC1NC(=O)[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 -US20090227595A1,7,O=C(c1ccccc1)c1cccc(Br)c1>>OC(c1ccccc1)c1cccc(Br)c1 -US20130217666A1,3,C#C[C@]1(O)CCN(C)C1=O.COC(=O)c1nc2c(s1)C(F)(F)COc1ccc(Br)cc1-2>>COC(=O)c1nc2c(s1)C(F)(F)COc1ccc(C#C[C@]3(O)CCN(C)C3=O)cc1-2 -US20140364433A1,1,Cc1ccc(-c2cnn(C)c2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.Cc1cccnc1Br>>Cc1ccc(-c2cnn(C)c2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncccc2C)c1 -US08344135B2,2,CC(=O)Nc1nc2ccc(Oc3ccc(Cl)c(N)c3)nc2s1.CC(C)(C#N)c1cccc(C(=O)O)c1Cl>>CC(=O)Nc1nc2ccc(Oc3ccc(Cl)c(NC(=O)c4cccc(C(C)(C)C#N)c4Cl)c3)nc2s1 -US04727078,3,O=C(O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(c1cccnc1)c1ccc2c(c1)OCO2>>O=C(O)CCCC/C=C(\c1cccnc1)c1ccc2c(c1)OCO2 -US20140080802A1,2,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1N.CCOC(=O)Cl>>CCOC(=O)Nc1cc(-c2cccs2)ccc1NC(=O)OC(C)(C)C -US20020025960A1,7,COC(=O)CS(=O)(=O)c1cc(C)ccc1[N+](=O)[O-]>>COC(=O)CS(=O)(=O)c1cc(C)ccc1N -US20120114765A1,2,CC1(C)CC(N)CC(C)(C)N1.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>CC1(C)CC(NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)CC(C)(C)N1 -US20110124597A1,1,O=C(OCc1ccccc1)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O.O=[N+]([O-])CC1OB(O)c2c(OCCCBr)cccc21>>O=C(OCc1ccccc1)c1cn(C2CC2)c2cc(N3CCN(CCCOc4cccc5c4B(O)OC5C[N+](=O)[O-])CC3)c(F)cc2c1=O -US08293734B2,1,Brc1cnc(Br)cn1.CC1(CO)Cn2cc([N+](=O)[O-])nc2O1>>CC1(COc2cnc(Br)cn2)Cn2cc([N+](=O)[O-])nc2O1 -US20130005707A1,6,CC(C)(C)OC(=O)Nc1cccc(CC2CCOCC2)n1>>Nc1cccc(CC2CCOCC2)n1 -US20120316161A1,6,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2c(c1)CCN2C>>CCCC(C(=O)O)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2c(c1)CCN2C -US20130150326A1,1,CCOC(=O)c1cccc(Sc2c(C)[nH]c3cc(Cl)ccc23)c1.CCn1cc(Br)cn1>>CCOC(=O)c1cccc(Sc2c(C)n(-c3cnn(CC)c3)c3cc(Cl)ccc23)c1 -US20140142114A1,1,C1CNCCN1.Fc1ccc2nc(Cl)ccc2c1>>Fc1ccc2nc(N3CCNCC3)ccc2c1 -US05723475,1,Fc1ccc(Cc2ccc(C3CCNCC3)cc2)cc1.O=C(CCCBr)Nc1ccccc1Cc1ccccc1>>O=C(CCCN1CCC(c2ccc(Cc3ccc(F)cc3)cc2)CC1)Nc1ccccc1Cc1ccccc1 -US04898455,8,CCCCCCc1ccc(-c2ccc([C@@H]3CC[C@@H](CO)CC3)cc2)nc1>>CCCCCCc1ccc(-c2ccc([C@@H]3CC[C@@H](C=O)CC3)cc2)nc1 -US20030216402A1,3,C#CCc1ccccc1.O=C(O)c1ccc(Cn2cnc3ccc(I)cc3c2=O)cc1>>O=C(O)c1ccc(Cn2cnc3ccc(C#CCc4ccccc4)cc3c2=O)cc1 -US20020091107A1,3,CC(=O)NC[C@H]1CN(c2ccc(C=O)cc2)C(=O)O1.O=C1CSC(=O)N1>>CC(=O)NC[C@H]1CN(c2ccc(/C=C3\SC(=O)NC3=O)cc2)C(=O)O1 -US05798344,10,Cc1ccc(-c2nc3ccccc3c(=O)n2-c2ccccc2)cc1.O=C1CCC(=O)N1Br>>O=c1c2ccccc2nc(-c2ccc(CBr)cc2)n1-c1ccccc1 -US20100240677A1,1,BrC1CCCC1.COc1cc(F)c(C=O)cc1O>>COc1cc(F)c(C=O)cc1OC1CCCC1 -US20060205774A1,2,C1=C(c2ccc(OCCCN3CCCCC3)cc2)CCNC1.O=C(O)c1ccc(F)cc1>>O=C(c1ccc(F)cc1)N1CC=C(c2ccc(OCCCN3CCCCC3)cc2)CC1 -US06197783B1,7,Cc1nc2c3c(ccn2c1C)C(=O)C(O)C(c1ccccc1)N3>>Cc1nc2c3c(ccn2c1C)C(O)C(O)C(c1ccccc1)N3 -US06432950B1,1,CCc1cc2c(Cl)nc(-c3cccnc3)nc2s1.NCc1ccc(Cl)c(Cl)c1>>CCc1cc2c(NCc3ccc(Cl)c(Cl)c3)nc(-c3cccnc3)nc2s1 -US05948917,9,COC(=O)c1ccc(Cl)c(C(=O)C(C(C)=O)C(=O)OC(C)(C)C)c1Cl>>COC(=O)c1ccc(Cl)c(C(=O)CC(C)=O)c1Cl -US08357707B2,6,COCOc1ccc(C(C)(O[Si](C)(C)C)C(F)(F)F)nc1>>COCOc1ccc(C(C)(O)C(F)(F)F)nc1 -US05919943,6,CCc1c(C(=O)C(N)=O)c2cc(OCCCC(=O)OC(C)(C)C)ccc2n1Cc1ccccc1>>CCc1c(C(=O)C(N)=O)c2cc(OCCCC(=O)O)ccc2n1Cc1ccccc1 -US07737295B2,7,N#Cc1cc(C(F)(F)F)ccc1N>>NCc1cc(C(F)(F)F)ccc1N -US20100048568A1,3,C#C[Si](C)(C)C.Nc1ncc(F)cc1I>>C[Si](C)(C)C#Cc1cc(F)cnc1N -US08980911B2,3,C=CC(=O)OCC.O=C(c1c(Cl)cc(Br)cc1Cl)n1ccc2cnccc21>>CCOC(=O)/C=C/c1cc(Cl)c(C(=O)n2ccc3cnccc32)c(Cl)c1 -US20110269712A1,2,COC(=O)C(N)CO.Cc1ccc(C)c(CC(=O)N2CCC(C(=O)O)CC2)c1>>COC(=O)C(CO)NC(=O)C1CCN(C(=O)Cc2cc(C)ccc2C)CC1 -US20090306062A1,1,COC(=O)C(C)(C)C[C@@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(C)cc1.COCCCN1C(=O)C(C)(C)Oc2ccc(CCl)cc21>>COCCCN1C(=O)C(C)(C)Oc2ccc(CO[C@@H]3CC[C@@H](CC(C)(C)C(=O)OC)N(S(=O)(=O)c4ccc(C)cc4)C3)cc21 -US07846944B2,7,O=[N+]([O-])c1ccc(Cl)c(Br)c1>>Nc1ccc(Cl)c(Br)c1 -US20030166628A1,3,CC(Br)C(=O)Cl.Fc1ccc2sccc2c1>>CC(Br)C(=O)c1cc2cc(F)ccc2s1 -US05373008,2,CN=C=S.Cc1ccc(N2CCOCC2)c(N)c1>>CNC(=S)Nc1cc(C)ccc1N1CCOCC1 -US20050197350A1,1,CNc1nc(Cl)nc2c1CCCC2.N[C@H]1CC[C@@H](CNC(=O)OCc2ccccc2)CC1>>CNc1nc(N[C@@H]2CC[C@H](CNC(=O)OCc3ccccc3)CC2)nc2c1CCCC2 -US20050154042A1,7,CCn1c(C=CC(=O)C[C@@H](O)CC(=O)OC)c(-c2ccc(F)cc2)c(C(C)C)c1C(=O)Nc1ccccc1>>CCn1c(C=C[C@@H](O)C[C@@H](O)CC(=O)OC)c(-c2ccc(F)cc2)c(C(C)C)c1C(=O)Nc1ccccc1 -US20150218186A1,3,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1ncc2cncc(I)c2n1.Cn1cc(B(O)O)cn1>>Cn1cc(-c2cncc3cnc(N[C@@H]4CCCC[C@@H]4NC(=O)OC(C)(C)C)nc23)cn1 -US04001418,6,CCN1CCC2(CC1)c1ccccc1Sc1c(OC)cccc12>>CCN1CCC2(CC1)c1ccccc1Sc1c(O)cccc12 -US20130231328A1,6,CC(C)(C)[Si](C)(C)OC[C@H]1CCc2sc3ncnc(OC4CCC(N5CC6(COC6)C5)CC4)c3c21>>OC[C@H]1CCc2sc3ncnc(OC4CCC(N5CC6(COC6)C5)CC4)c3c21 -US20030073846A1,7,O=[N+]([O-])c1cc(OC[C@@H](O)CN(Cc2ccccc2)[C@H](CO)Cc2ccc(OCc3ccccc3)cc2)ccc1OCc1ccccc1>>Nc1cc(OC[C@@H](O)CN(Cc2ccccc2)[C@H](CO)Cc2ccc(OCc3ccccc3)cc2)ccc1OCc1ccccc1 -US20100130446A1,4,O=C(CCC(=O)C(CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1)c1ncc(CO)s1.[NH4+]>>O=S(=O)(c1ccc(C(CC2CCOCC2)c2ccc(-c3ncc(CO)s3)[nH]2)cc1)C1CC1 -US08486954B2,2,CC(=O)OCc1nccc(Oc2ccc3[nH]c(C)cc3c2F)n1.O=C=Nc1cccc(C(F)(F)F)c1>>CC(=O)OCc1nccc(Oc2ccc3c(cc(C)n3C(=O)Nc3cccc(C(F)(F)F)c3)c2F)n1 -US20050020587A1,1,BrCC1CC1.Oc1ccccc1S>>Oc1ccccc1SCC1CC1 -US20050165064A1,2,CS(=O)(=O)Cl.O=C1C[C@H](O)CN1Cc1ccc(Oc2ccc(F)cc2)nc1>>CS(=O)(=O)O[C@H]1CC(=O)N(Cc2ccc(Oc3ccc(F)cc3)nc2)C1 -US20090286768A1,2,CN(C)CC(=O)Cl.Nc1nccn2c(C3CCNCC3)nc(I)c12>>CN(C)CC(=O)N1CCC(c2nc(I)c3c(N)nccn23)CC1 -US20030225268A1,1,CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2.Clc1ccc(I)cn1>>CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2c1ccc(Cl)nc1 -US20020143020A1,1,BrCC1CC1.OCc1c(F)cc(O)cc1F>>OCc1c(F)cc(OCC2CC2)cc1F -US07449490B2,6,CCOC(=O)c1c(-c2ccccc2OC)csc1N1C(=O)c2ccccc2C1=O>>COc1ccccc1-c1csc(N2C(=O)c3ccccc3C2=O)c1C(=O)O -US08193202B2,1,C=CCC1(C(=O)Nc2cccc(Cl)c2)CCNCC1.Cc1c[nH]c2ncnc(Cl)c12>>C=CCC1(C(=O)Nc2cccc(Cl)c2)CCN(c2ncnc3[nH]cc(C)c23)CC1 -US07598419B2,3,COc1cc(C=CC=O)cc(OC)c1O.N#CCC(=O)O>>COc1cc(/C=C/C=C(\C#N)C(=O)O)cc(OC)c1O -US20010053851A1,2,Nc1nccs1.O=C(O)C(CC1CCCC1)c1ccc(C#CCN2CCOCC2)cc1>>O=C(Nc1nccs1)C(CC1CCCC1)c1ccc(C#CCN2CCOCC2)cc1 -US20050215556A1,1,C=CCBr.Cc1cc(Br)c(O)c([N+](=O)[O-])c1>>C=CCOc1c(Br)cc(C)cc1[N+](=O)[O-] -US20140142114A1,6,CC(C)(C)OC(=O)N1CCC(Nc2ccc(C#N)c(C(F)(F)F)c2)CC1>>N#Cc1ccc(NC2CCNCC2)cc1C(F)(F)F -US20080015214A1,1,Clc1ccc2c(C3CCNCC3)cn(Cc3ccccc3)c2c1.O=CC1CCCCCCC1>>Clc1ccc2c(C3CCN(CC4CCCCCCC4)CC3)cn(Cc3ccccc3)c2c1 -US20100152169A1,9,COC(=O)c1ccc(C)c(-n2cnc3c(C(N)=O)cc(I)cc3c2=O)c1>>COC(=O)c1ccc(C)c(-n2cnc3c(C#N)cc(I)cc3c2=O)c1 -US20100222393A1,2,CS(=O)(=O)Cl.Cc1nccn1CCO>>Cc1nccn1CCOS(C)(=O)=O -US20040077696A1,1,ClCc1cnc(Nc2ccccn2)s1.O=C(NC1CC1)c1ccc(F)c(O)c1>>O=C(NC1CC1)c1ccc(F)c(OCc2cnc(Nc3ccccn3)s2)c1 -US09073864B2,3,CON(C)C(=O)c1ccc(Br)cn1.OB(O)c1ccc(Cl)cc1>>CON(C)C(=O)c1ccc(-c2ccc(Cl)cc2)cn1 -US20150126510A1,1,Cc1cc(Br)cc(C)c1N.Clc1nc(Cl)nc(Cl)n1>>Cc1cc(Br)cc(C)c1Nc1nc(Cl)nc(Cl)n1 -US20130203750A1,1,Brc1cccnc1.CC(C)(C)OC(=O)N1CC[C@H](Nc2ccc(F)c(Cl)c2)C1>>CC(C)(C)OC(=O)N1CC[C@H](N(c2cccnc2)c2ccc(F)c(Cl)c2)C1 -US20100029710A1,1,CCC(Cl)=Nc1c(C)cc(C(=O)C(C)C)nc1Cl.N[C@H]1CCc2cc(Br)ccc21>>CCC(=Nc1c(C)cc(C(=O)C(C)C)nc1Cl)N[C@H]1CCc2cc(Br)ccc21 -US04788196,7,O=[N+]([O-])c1ccc(N2CCN(c3ccncc3)CC2)cc1>>Nc1ccc(N2CCN(c3ccncc3)CC2)cc1 -US07101886B2,7,COc1cc(CC(=O)N2CCN(c3nsc4ccccc34)CC2)c([N+](=O)[O-])cc1OC>>COc1cc(CCN2CCN(c3nsc4ccccc34)CC2)c([N+](=O)[O-])cc1OC -US05204333,6,COc1ccc(COCC2(c3ccc(F)c(F)c3)COC(C)(C)OC2)cc1>>CC1(C)OCC(CO)(c2ccc(F)c(F)c2)CO1 -US07999132B2,2,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1N.O=C(O)c1ccc(-n2cccc2)cc1>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(-n2cccc2)cc1 -US07378417B2,2,CCNS(=O)(=O)c1cccc(N)c1.O=C(O)c1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>CCNS(=O)(=O)c1cccc(NC(=O)c2cnn3c(C(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)c1 -US20080318923A1,6,COC(=O)COC1(c2ccccc2OC)C(=O)Nc2ccc(Cl)cc21>>COc1ccccc1C1(OCC(=O)O)C(=O)Nc2ccc(Cl)cc21 -US20120040837A1,9,Fc1ccc(Nc2nc(Cl)nc(NCc3ccc(Cl)nc3)n2)cc1C(F)(F)F.NN>>NNc1nc(NCc2ccc(Cl)nc2)nc(Nc2ccc(F)c(C(F)(F)F)c2)n1 -US07569578B2,6,Cc1cc(CC(c2cccc(Br)n2)N2C(=O)c3ccccc3C2=O)cc2cn(COCC[Si](C)(C)C)nc12>>Cc1cc(CC(N)c2cccc(Br)n2)cc2cn(COCC[Si](C)(C)C)nc12 -US05556977,9,COC(=O)COc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1.N>>NC(=O)COc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1 -US20110294780A1,1,CN(C)CCCCl.COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)NC4=O)ccc32)c(C(F)(F)F)c1>>COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)N(CCCN(C)C)C4=O)ccc32)c(C(F)(F)F)c1 -US20130053409A1,1,COc1cc(F)c([N+](=O)[O-])cc1N.Clc1ncc(Cl)c(-c2cnn3ccccc23)n1>>COc1cc(F)c([N+](=O)[O-])cc1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1 -US20120288492A1,2,CCOC(=O)c1nc(-c2ccc(N)cc2)nc(N2CCOCC2)c1OCC.C[Si](C)(C)N=C=O>>CCOC(=O)c1nc(-c2ccc(NC(N)=O)cc2)nc(N2CCOCC2)c1OCC -US20140371278A1,9,COC(=O)c1cc(SCc2ccc(OC)cc2)c(F)c(F)c1Nc1ccccc1F.[N-]=[N+]=[N-]>>COC(=O)c1cc(SCc2ccc(OC)cc2)c(N=[N+]=[N-])c(F)c1Nc1ccccc1F -US20140024637A1,2,CS(=O)(=O)Cl.O=C(OCc1ccccc1)N1CC[C@H](CO)C[C@@H]1c1ccc(F)c(F)c1>>CS(=O)(=O)OC[C@H]1CCN(C(=O)OCc2ccccc2)[C@@H](c2ccc(F)c(F)c2)C1 -US20120010189A1,1,CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1.CN1CCN(Cc2ccc(O)cc2F)CC1>>CN1CCN(Cc2ccc(OC3CN(C(=O)OC(C)(C)C)C3)cc2F)CC1 -US07772253B2,2,CCOc1cc(CN2CCC(N)CC2)ccc1Cl.Cc1ccc(C(=O)Cl)cc1>>CCOc1cc(CN2CCC(NC(=O)c3ccc(C)cc3)CC2)ccc1Cl -US20150025280A1,9,CCOc1ccccc1Br>>CCOc1ccccc1 -US08669255B2,2,O=C(Cl)c1ccc(C(F)(F)F)cc1.O=C1CNC[C@@H]2C[C@@H](Oc3cnc(C4CC4)cn3)CN12>>O=C(c1ccc(C(F)(F)F)cc1)N1CC(=O)N2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2C1 -US20080176862A1,6,COc1ccc(C(=O)C(=O)c2cc(Cl)ccn2)cc1>>O=C(C(=O)c1cc(Cl)ccn1)c1ccc(O)cc1 -US07638648B2,3,C#Cc1cc(C(C)(C)C)c(OC(C)C)c(C=O)c1C.COC(=O)Cc1ccc(I)cc1>>COC(=O)Cc1ccc(C#Cc2cc(C(C)(C)C)c(OC(C)C)c(C=O)c2C)cc1 -US20140155406A1,7,N#Cc1nccnc1Cl>>NCc1nccnc1Cl -US20060205740A1,1,N#CCCN.O=Cc1ccc(C#Cc2cncnc2Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)o1>>N#CCCNCc1ccc(C#Cc2cncnc2Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)o1 -US06750216B2,2,COC(=O)N1C[C@H](CN2CCCC2)NC[C@H]1CO.O=C(O)Cc1ccc(Cl)c(Cl)c1>>COC(=O)N1C[C@H](CN2CCCC2)N(C(=O)Cc2ccc(Cl)c(Cl)c2)C[C@H]1CO -US20060063772A1,7,COC(=O)c1cc(-c2cc(C)ccc2F)on1>>Cc1ccc(F)c(-c2cc(CO)no2)c1 -US05773612,2,CCN(CC)C(=O)Nc1ccc(S(=O)(=O)Cl)cc1.NC1(c2ccccc2Cl)C(=O)Nc2ccc(Cl)cc21>>CCN(CC)C(=O)Nc1ccc(S(=O)(=O)N2C(=O)C(N)(c3ccccc3Cl)c3cc(Cl)ccc32)cc1 -US20080269210A1,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.C[C@H](O)CNC(=O)c1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1>>C[C@H](O)CNC(=O)c1cccc(-c2cc3nc(-c4ccc(N)nc4)nc(N4CCOCC4)c3s2)c1 -US08853215B2,6,CCOC(=O)CC(=O)N1CCN(c2ccccc2C(C)(C)C)CC1>>CC(C)(C)c1ccccc1N1CCN(C(=O)CC(=O)O)CC1 -US05620987,9,CC(C)CCN1CCC[C@]1(C(N)=O)C(=O)OCc1ccccc1>>CC(C)CCN1CCC[C@H]1C(N)=O -US05242924,7,CCOC(=O)Cc1ccncc1>>CCOC(=O)CC1CCNCC1 -US20130053397A1,7,CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(/C=C/C(=O)OCC)cc2c1c(C)cn2C(C)C>>CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(CCC(=O)OCC)cc2c1c(C)cn2C(C)C -US08586571B2,3,CC(=O)c1ccc(C(=O)N2CC(Oc3ccc(F)cc3C(C)(C)C)C2)cc1.C[Mg+]>>CC(C)(C)c1cc(F)ccc1OC1CN(C(=O)c2ccc(C(C)(C)O)cc2)C1 -US20100125137A1,1,Cc1ccnc(Cl)c1NC(=O)c1cccnc1Cl.NC1CC1>>Cc1ccnc(Cl)c1NC(=O)c1cccnc1NC1CC1 -US20130053381A1,1,CC(C)n1nccc1-c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)F.CCC(=O)Cl>>CCC(=O)N(n1c(=O)[nH]c2cc(C(F)F)c(-c3ccnn3C(C)C)cc2c1=O)S(C)(=O)=O -US20060276464A1,6,CN(CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F)C(=O)N[C@H]1CCN(C(=O)OC(C)(C)C)C1>>CN(CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F)C(=O)N[C@H]1CCNC1 -US20040121965A1,2,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](N)C(C)(C)SC.CN(C(=O)OC(C)(C)C)[C@H](C(=O)O)C(C)(C)c1ccccc1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1)C(C)(C)SC -US20070155727A1,6,COC(=O)c1ccc(CN(C)CC2(CN(C)CC(=O)Nc3ccc(Oc4ccccc4)cc3)CCCC2)cc1>>CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)CC1(CN(C)Cc2ccc(C(=O)O)cc2)CCCC1 -US20110112103A1,1,CC(C)(C)c1ccc(Br)cc1.Cc1nc(CC2CCNCC2)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1>>Cc1nc(CC2CCN(c3ccc(C(C)(C)C)cc3)CC2)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1 -US20040122057A1,3,Brc1ccncc1.CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(B2OC(C)(C)C(C)(C)O2)cc1F>>CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(-c2ccncc2)cc1F -US07732446B1,4,COc1cc2c(NC(N)=S)cnc(CNC(=O)OC(C)(C)C)c2cc1OC.O=C(CBr)c1ccccc1>>COc1cc2c(Nc3nc(-c4ccccc4)cs3)cnc(CNC(=O)OC(C)(C)C)c2cc1OC -US20150191437A1,3,COc1c(I)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C.OB(O)c1ccc2cc(O)ccc2c1>>COc1c(-c2ccc3cc(O)ccc3c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C -US04287340,9,COC(=O)C1C(=O)C(C)SC1C.NO>>COC(=O)C1C(=NO)C(C)SC1C -US08252795B2,1,COc1ccc(C#N)cc1N.N#Cc1cnc2c(NCC(F)(F)F)cc(Cl)nn12>>COc1ccc(C#N)cc1Nc1cc(NCC(F)(F)F)c2ncc(C#N)n2n1 -US08975254B2,2,C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.O=C(O)c1cscn1>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cscn1 -US20060111347A1,8,O=C(N[C@@H]1CCCc2c1ccc(CO)c2[N+](=O)[O-])C(F)(F)F>>O=Cc1ccc2c(c1[N+](=O)[O-])CCC[C@H]2NC(=O)C(F)(F)F -US20150080369A1,1,Cc1ccc(N(CC(C)C)S(=O)(=O)c2cccc(O)c2)c(C)c1.OCCN1CCOCC1>>Cc1ccc(N(CC(C)C)S(=O)(=O)c2cccc(OCCN3CCOCC3)c2)c(C)c1 -US09051340B2,1,Clc1ccc(Br)c(CBr)c1.O=C1CCCc2c(O)cccc21>>O=C1CCCc2c(OCc3cc(Cl)ccc3Br)cccc21 -US04029787,1,CN(Cc1ccccc1)C(=O)c1ccc(Cl)c(S(N)(=O)=O)c1.CN1CCNCC1>>CN1CCN(c2ccc(C(=O)N(C)Cc3ccccc3)cc2S(N)(=O)=O)CC1 -US20150126490A1,1,CN(C[C@H](O)c1cccc(Cl)c1)C(=O)OC(C)(C)C.O=C1NC(=O)c2ccccc21>>CN(C[C@H](c1cccc(Cl)c1)N1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C -US20130165485A1,1,COC(=O)c1cc[nH]n1.FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(Cl)=NO1>>COC(=O)c1ccn(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)n1 -US20040087573A1,1,C1COCCN1.O=C1CCN(c2ccc(CN3CCOCC3)cc2)CC1>>c1cc(N2CCC(N3CCOCC3)CC2)ccc1CN1CCOCC1 -US20150175601A1,2,C=CC(=O)Cl.CC(=O)OCc1ccc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2c1-c1cccc(N)c1>>C=CC(=O)Nc1cccc(-c2c(COC(C)=O)ccc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc23)c1 -US20060094767A1,1,C=O.C[C@]1(CN2CCC(Nc3ccc(OC(F)(F)F)cc3)CC2)Cn2cc([N+](=O)[O-])nc2O1>>CN(c1ccc(OC(F)(F)F)cc1)C1CCN(C[C@@]2(C)Cn3cc([N+](=O)[O-])nc3O2)CC1 -US20050239832A1,9,CC(C)(C)Cc1ccc2c(c1)C(N=[N+]=[N-])CCN2C(=O)OCc1ccccc1>>CC(C)(C)Cc1ccc2c(c1)C(N)CCN2C(=O)OCc1ccccc1 -US20100120801A1,1,CN(C)CCn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCNCC1.COc1ccc(CN2C(=O)Cc3c(Cl)ncnc32)c(OC)c1>>COc1ccc(CN2C(=O)Cc3c(N4CCC(c5nc(-c6ccc(F)c(C(F)(F)F)c6)cn5CCN(C)C)CC4)ncnc32)c(OC)c1 -US06329396B1,6,COc1ccc(C(=C(F)F)C(F)(F)F)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1>>COc1ccc(C(=C(F)F)C(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 -US09156827B2,7,COc1ccc2c(c1C#CCN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O>>COc1ccc2c(c1CCCN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O -US05885979,6,CCOC(=O)C[C@H]1O[C@H](c2ccc(OCC)cc2OC)c2cc(Cl)ccc2N(CC(C)(C)C)C1=O>>CCOc1ccc([C@H]2O[C@H](CC(=O)O)C(=O)N(CC(C)(C)C)c3ccc(Cl)cc32)c(OC)c1 -US06306880B1,7,CCOC(=O)/C=C/C#Cc1ccc(C(F)(F)F)cc1>>OC/C=C/C#Cc1ccc(C(F)(F)F)cc1 -US20080318923A1,2,COc1ccc(S(=O)(=O)Cl)c(OC(F)(F)F)c1.COc1ccccc1C1(N2CCCC[C@H]2C(=O)OCc2ccccc2)C(=O)Nc2ccc(Cl)cc21>>COc1ccc(S(=O)(=O)N2C(=O)C(c3ccccc3OC)(N3CCCC[C@H]3C(=O)OCc3ccccc3)c3cc(Cl)ccc32)c(OC(F)(F)F)c1 -US20120035370A1,3,CC[Mg+].O=Cc1ccc(Br)nc1>>CCC(O)c1ccc(Br)nc1 -US08349880B2,3,C=CCC(c1ccc(F)cc1)c1nc(Nc2ccc(-n3cnc(Cl)c3)c(OC)c2)nn1CC=C>>COc1cc(Nc2nc3n(n2)CC=CCC3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1 -US07423051B2,2,CCC(=O)Cl.Nc1nc(NC2CCNCC2)ccc1C(=O)c1ccccc1F>>CCC(=O)N1CCC(Nc2ccc(C(=O)c3ccccc3F)c(N)n2)CC1 -US20140081025A1,2,CNCCc1ccn(-c2ccc(F)cn2)n1.O=C(O)c1cc(Cl)ccc1-n1nccn1>>CN(CCc1ccn(-c2ccc(F)cn2)n1)C(=O)c1cc(Cl)ccc1-n1nccn1 -US07208598B2,1,CCC(C)n1cnc2c(Cl)nc(Cl)nc21.NCc1cccc(I)c1>>CCC(C)n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc21 -US07550474B2,6,CCOC(=O)Cc1c(C#N)ccc(NCC(F)(F)c2ccc(C)cn2)c1F>>Cc1ccc(C(F)(F)CNc2ccc(C#N)c(CC(=O)O)c2F)nc1 -US07592347B2,6,CC(C)N1CCN(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)[C@@H](C)C1>>CC(C)N1CCN(C(=O)C2CCNCC2)[C@@H](C)C1 -US20090099200A1,1,Clc1nc2ccccc2s1.O=C(c1ccccc1C(F)(F)F)N1CCNCC1>>O=C(c1ccccc1C(F)(F)F)N1CCN(c2nc3ccccc3s2)CC1 -US20150080393A1,6,COC(=O)C1CC2(CCN1)CCN(c1cc(O[C@H](c3ccc(Cl)cc3-n3ccc(C)n3)C(F)(F)F)nc(N)n1)CC2>>Cc1ccn(-c2cc(Cl)ccc2[C@@H](Oc2cc(N3CCC4(CCNC(C(=O)O)C4)CC3)nc(N)n2)C(F)(F)F)n1 -US07268128B2,3,C=CC(=O)OC.COc1cc(Br)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1>>COC(=O)/C=C/c1ccc(-c2nc3c(C)nn(C4CCCCC4)c3c(=O)[nH]2)c(OC)c1 -US20150218096A1,1,Brc1ccc2c(I)n[nH]c2c1.O=C(Cl)c1c(Cl)cccc1C(F)(F)F>>O=C(c1c(Cl)cccc1C(F)(F)F)n1nc(I)c2ccc(Br)cc21 -US20110152257A1,2,CC(=O)OCC(C)(C)C(=O)Cl.Nc1ccc(I)cn1>>CC(=O)OCC(C)(C)C(=O)Nc1ccc(I)cn1 -US20090286778A1,6,CC(C)(C)OC(=O)Nc1cccc(NCc2cccc([N+](=O)[O-])c2)c1>>Nc1cccc(NCc2cccc([N+](=O)[O-])c2)c1 -US20080194549A1,1,CC(C)(C)OC(=O)N1C[C@@H](C(C)(C)O[SiH2]C(C)(C)C)[C@H](C=O)C1.CC(C)N>>CC(C)NC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1C(C)(C)O[SiH2]C(C)(C)C -US20140315881A1,2,Cc1ccc([C@@H](N)c2ccccc2)c(C)c1.Cc1cnccc1C(=O)c1cc2cc(CC(=O)O)ccc2o1>>Cc1ccc([C@@H](NC(=O)Cc2ccc3oc(C(=O)c4ccncc4C)cc3c2)c2ccccc2)c(C)c1 -US20070254880A1,2,CCCS(=O)(=O)N1CCC(c2ccccn2)(C(C)(C)N)CC1.O=C(Cl)c1c(F)ccc(F)c1Cl>>CCCS(=O)(=O)N1CCC(c2ccccn2)(C(C)(C)NC(=O)c2c(F)ccc(F)c2Cl)CC1 -US07285563B2,1,CI.Oc1cc2cccc(Br)c2cn1>>COc1cc2cccc(Br)c2cn1 -US07932272B2,7,N#Cc1ccc(OCc2ccccn2)cc1>>NCc1ccc(OCc2ccccn2)cc1 -US20120190679A1,2,CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1.N[C@@H](CCO)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](CCO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 -US20120094995A1,2,CN1C2CCC1(C(N)c1ccccc1)CC2.Cc1cccc(C)c1C(=O)O>>Cc1cccc(C)c1C(=O)NC(c1ccccc1)C12CCC(CC1)N2C -US20080269277A1,2,NNC(=O)c1cc2cc(Cl)ncc2[nH]1.O=C=Nc1cccs1>>O=C(NNC(=O)c1cc2cc(Cl)ncc2[nH]1)Nc1cccs1 -US04446323,2,COc1cccc(OC)c1C(=O)Cl.c1ccc2c(c1)NCC1CCCN21>>COc1cccc(OC)c1C(=O)N1CC2CCCN2c2ccccc21 -US08063099B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c1.O=C(O)c1cccc2c1NCCO2>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2cccc3c2NCCO3)c1 -US20080249309A1,7,O=[N+]([O-])c1c2ccccc2cc2ccccc12>>Nc1c2ccccc2cc2ccccc12 -US20120142633A1,2,COCC(=O)Cl.Cc1[nH]c2c(-c3cc(F)ccc3OCC3CC3)ccnc2c1C(=O)N[C@@H]1CC[C@@H](N)CC1>>COCC(=O)N[C@@H]1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4cc(F)ccc4OCC4CC4)ccnc23)CC1 -US20090143592A1,6,CCOC(=O)CCNC(=O)c1ccc(C(NC(=O)Nc2ccc(OC(F)(F)F)cc2)[C@H]2CC[C@@H](C(C)(C)C)CC2)cc1>>CC(C)(C)[C@@H]1CC[C@H](C(NC(=O)Nc2ccc(OC(F)(F)F)cc2)c2ccc(C(=O)NCCC(=O)O)cc2)CC1 -US04810282,2,COC(=O)Nc1nc(C)nc(OC)n1.Cn1cc(-c2ccccc2S(N)(=O)=O)cn1>>COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2-c2cnn(C)c2)n1 -US20150246922A1,3,Cc1cc(Br)c2c(c1)cc1n2CCCNC1=O.OB(O)c1ccc(F)c(F)c1>>Cc1cc(-c2ccc(F)c(F)c2)c2c(c1)cc1n2CCCNC1=O -US20100069362A1,6,CN(Cc1ccc(C(=O)Cn2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)cc1)C(=O)C(F)(F)F>>CNCc1ccc(C(=O)Cn2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)cc1 -US20080146566A1,1,Cc1ccc(C(=O)O)cc1-n1ccc2ccc(O)cc2c1=O.ClCCBr>>Cc1ccc(C(=O)O)cc1-n1ccc2ccc(OCCCl)cc2c1=O -US20110065725A1,2,COc1ccccc1-n1nnc(C(=O)O)c1C.Cc1cccc(N)n1>>COc1ccccc1-n1nnc(C(=O)Nc2cccc(C)n2)c1C -US20110275797A1,3,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(Br)ccc1OCc1ccccc1.CC1(C)OB(c2ccoc2)OC1(C)C>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(-c2ccoc2)ccc1OCc1ccccc1 -US08071592B2,1,COc1ccc2ccc(=O)n(CC=O)c2c1.O=C(NC[C@@H]1CNC[C@@H]1O)OCc1ccccc1>>COc1ccc2ccc(=O)n(CCN3C[C@H](O)[C@H](CNC(=O)OCc4ccccc4)C3)c2c1 -US20050277643A1,6,CC(=O)N1CC(C)(C)c2ccc(Nc3ncnc4c3CCN(c3ncccc3Cl)C4)cc21>>CC1(C)CNc2cc(Nc3ncnc4c3CCN(c3ncccc3Cl)C4)ccc21 -US20080312234A1,2,COCCOc1nc(C(F)(F)F)ccc1C=CC(=O)O.CS(=O)(=O)Nc1c(F)cc(CN)cc1C#N>>COCCOc1nc(C(F)(F)F)ccc1C=CC(=O)NCc1cc(F)c(NS(C)(=O)=O)c(C#N)c1 -US08188113B2,7,CC(C)(C)n1nc([N+](=O)[O-])c2ccccc21>>CC(C)(C)n1nc(N)c2ccccc21 -US06774132B1,1,CCCC=O.O=C1Nc2ccccc2C12CCCNC2>>CCCCN1CCCC2(C1)C(=O)Nc1ccccc12 -US20140088029A1,1,CC(=O)OC[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.COc1cc(O)ccc1C=O>>COc1cc(O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)ccc1C=O -US05977410,2,NCCOc1ccc(OCC(F)(F)F)cc1.O=C(Cl)c1c(F)cccc1F>>O=C(NCCOc1ccc(OCC(F)(F)F)cc1)c1c(F)cccc1F -US20110112120A9,1,CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OB(O)c1cccc(Br)c1>>CCCCc1nc(C)n(-c2cccc(Br)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20150265617A1,1,Clc1c(-c2ccccc2)nnc2[nH]nc(C3CC3)c12.O=C(CCl)N1CCCC1>>O=C(Cn1nc(C2CC2)c2c(Cl)c(-c3ccccc3)nnc21)N1CCCC1 -US20120122848A1,4,COc1cc2c(cc1N)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1.ClCCOCCCl>>COc1cc2c(cc1N1CCOCC1)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1 -US07625932B2,3,CC(CNS(=O)(=O)C(C)C)c1ccc(I)cc1.CCOC(=O)c1c(B2OC(C)(C)C(C)(C)O2)c(C#N)c(CC)n1C>>CCOC(=O)c1c(-c2ccc(C(C)CNS(=O)(=O)C(C)C)cc2)c(C#N)c(CC)n1C -US07235579B2,1,COc1ccc(C2CNC(=O)C2)cc1O.OB(O)c1ccc(Cl)cc1>>COc1ccc(C2CNC(=O)C2)cc1Oc1ccc(Cl)cc1 -US06399614B1,2,COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2N)CC1.CS(=O)(=O)Cl>>COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2NS(C)(=O)=O)CC1 -US06239151B1,6,CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)[C@@H](C)O)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)[C@@H](C)O)[C@H](C/C=C/c1ccccc1)C(=O)NO -US20080058349A1,3,COc1cccc(B(O)O)c1.CS(=O)(=O)Oc1ccc(C2(c3cccc(Br)c3)N=C(N)N3CCCN=C32)cc1>>COc1cccc(-c2cccc(C3(c4ccc(OS(C)(=O)=O)cc4)N=C(N)N4CCCN=C43)c2)c1 -US20100261727A1,3,COc1cccc2sc(B(O)O)cc12.O=[N+]([O-])c1ccc(I)cc1>>COc1cccc2sc(-c3ccc([N+](=O)[O-])cc3)cc12 -US20090105473A1,1,CS(N)(=O)=O.O=c1c(C2=NS(=O)(=O)c3cc(I)ccc3N2)c(O)c2cccn2n1Cc1ccc(F)cc1>>CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cccn3n(Cc3ccc(F)cc3)c1=O)N2 -US20020094989A1,3,CON(C)C(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1cc(C=O)co1>>CON(C)C(=O)/C=C/c1coc(C)c1 -US20100249161A1,4,Cc1c(Cl)cc(C(C)(C)C)c(O)c1C=O.NC(=O)c1cc(F)ccc1N>>Cc1c(Cl)cc(C(C)(C)C)c(O)c1-c1nc2ccc(F)cc2c(=O)[nH]1 -US07678925B2,9,NO.O=C(O)C(=O)CC(O)(Cc1c[nH]c2ccccc12)C(=O)O>>O=C(O)C(CC(O)(Cc1c[nH]c2ccccc12)C(=O)O)=NO -US20120114765A1,1,CC(=O)c1cc([N+](=O)[O-])c(Cl)s1.Sc1cnc2ccccc2n1>>CC(=O)c1cc([N+](=O)[O-])c(Sc2cnc3ccccc3n2)s1 -US20090137499A1,9,COC(=O)c1ccc(C(O)c2ccc(SC)cc2)c(O)c1>>COC(=O)c1ccc(Cc2ccc(SC)cc2)c(O)c1 -US20120283254A1,2,N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1.O=C(O)C1CCC(C(F)(F)F)CC1>>O=C(N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1)C1CCC(C(F)(F)F)CC1 -US08501732B2,2,COC(=O)c1c(CN)c(=O)c2ccc(OC)cc2n1-c1ccccc1.O=C(Cl)c1ccc(F)cc1>>COC(=O)c1c(CNC(=O)c2ccc(F)cc2)c(=O)c2ccc(OC)cc2n1-c1ccccc1 -US04599335,1,CC(CCl)Cc1ccc(C(C)(C)C)cc1.N[C@@H]1CCCC[C@H]1N>>CC(CN[C@@H]1CCCC[C@H]1N)Cc1ccc(C(C)(C)C)cc1 -US05352684,1,CC(=O)C1=C(C)NC(C)=C(C(=O)CCCCCBr)C1c1cccc([N+](=O)[O-])c1.c1ccc(C2(c3ccccc3)CCNCC2)cc1>>CC(=O)C1=C(C)NC(C)=C(C(=O)CCCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1 -US04767765,2,CC(C)(C)C(=O)Cl.Cc1nnc2ccc(-c3cccc(N)c3)nn12>>Cc1nnc2ccc(-c3cccc(NC(=O)C(C)(C)C)c3)nn12 -US20070141684A1,2,CCC[C@@H](C)CO.CS(=O)(=O)Cl>>CCC[C@@H](C)COS(C)(=O)=O -US06297282B1,1,O=[N+]([O-])c1cccc(Cl)c1Cl.Sc1ccc(Cl)cc1Cl>>O=[N+]([O-])c1cccc(Cl)c1Sc1ccc(Cl)cc1Cl -US20050282857A1,3,C=C(NC(C)=O)C(=O)OC.Cc1cc(Br)cc(Cl)c1N>>COC(=O)/C(=C\c1cc(C)c(N)c(Cl)c1)NC(C)=O -US05344845,7,COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1OCCn1ccnc1>>COc1cc(CCC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1OCCn1ccnc1 -US20060293344A1,1,CC(=O)c1c(-c2ccc(Br)cc2)nn2c(Cl)cccc12.CCCCN>>CCCCNc1cccc2c(C(C)=O)c(-c3ccc(Br)cc3)nn12 -US07094789B2,9,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](N=[N+]=[N-])CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](N)CC1 -US20100256356A1,2,COCCN1CCC(Nc2nn(Cc3ccc(OC)cc3)c3nccc(Oc4ccc(N)cc4F)c23)CC1.O=C(O)c1ccnn(-c2ccc(F)cc2)c1=O>>COCCN1CCC(Nc2nn(Cc3ccc(OC)cc3)c3nccc(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)c23)CC1 -US20050090498A1,4,CC(N)=S.O=C(CBr)c1ccc(Cl)c([N+](=O)[O-])c1>>Cc1nc(-c2ccc(Cl)c([N+](=O)[O-])c2)cs1 -US06362336B1,1,COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O.Cc1cc(N(C)CCO)cc(C)n1>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN(C)c1cc(C)nc(C)c1 -US20140005132A1,3,C#C[Mg+].COCO[C@@H]1C[C@]2(C)[C@@H](C=O)CC[C@]2(O)C2CC[C@]3(O)C[C@@H](O[C@@H]4O[C@@H](C)[C@H](OCOC)[C@H]5OC(C)(C)O[C@@H]45)C[C@H]4OC(C)(C)OC[C@]43C21>>C#CC(O)[C@H]1CC[C@]2(O)C3CC[C@]4(O)C[C@@H](O[C@@H]5O[C@@H](C)[C@H](OCOC)[C@H]6OC(C)(C)O[C@@H]56)C[C@H]5OC(C)(C)OC[C@]54C3[C@H](OCOC)C[C@]12C -US04118390,2,C#CCNCC=O.O=C=Nc1ncc(I)s1>>C#CCN(CC=O)C(=O)Nc1ncc(I)s1 -US06291482B1,9,NO.O=CC1=Cc2cc(Cc3cccnc3)ccc2OC1>>ON=CC1=Cc2cc(Cc3cccnc3)ccc2OC1 -US20040122057A1,3,CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(Br)cc1F.OB(O)c1ccccc1>>CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(-c2ccccc2)cc1F -US20150119385A1,1,CCO.N#Cc1cnc(N)cc1Cl>>CCOc1cc(N)ncc1C#N -US20140249137A1,6,CCOC(=O)C(O[Si](C)(C)C(C)(C)C)c1ccc(-c2ncc(Cl)c(Nc3cc(C4CC4)[nH]n3)n2)s1>>CCOC(=O)C(O)c1ccc(-c2ncc(Cl)c(Nc3cc(C4CC4)[nH]n3)n2)s1 -US07749530B2,1,CCn1nc(C)cc1C(=O)Nc1ccc(C(=O)c2ccc3c(c2)C(=CO)C(=O)N3)cc1.Nc1ccc(N2CCOCC2)cc1>>CCn1nc(C)cc1C(=O)Nc1ccc(C(=O)c2ccc3c(c2)C(=CNc2ccc(N4CCOCC4)cc2)C(=O)N3)cc1 -US20020058665A1,6,CSCC[C@H](NC(=O)c1cc(OC(Cc2cncn2C)c2nccs2)ccc1CCc1ccc(F)cc1)C(=O)OC(C)(C)C>>CSCC[C@H](NC(=O)c1cc(OC(Cc2cncn2C)c2nccs2)ccc1CCc1ccc(F)cc1)C(=O)O -US20120101124A1,6,CCOC(=O)CCCc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c2c1ccn2C>>CC(C)Oc1ccc(-c2nc(-c3ccc(CCCC(=O)O)c4ccn(C)c34)no2)cc1Cl -US20050222128A1,7,COC(=O)/C=C/c1cccc(CC(C)=O)c1>>COC(=O)CCc1cccc(CC(C)=O)c1 -US20050171163A1,3,CC[Mg+].CON(C)C(=O)CS(C)(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>CCC(=O)CS(C)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 -US20130190338A1,2,COC(=O)c1cccc(CSc2ccc(F)cc2N)c1.O=S(=O)(Cl)c1cc2ccccc2o1>>COC(=O)c1cccc(CSc2ccc(F)cc2NS(=O)(=O)c2cc3ccccc3o2)c1 -US06215001B1,1,NCCCCCn1ccnc1.O=CCCc1ccccc1>>c1ccc(CCCNCCCCCn2ccnc2)cc1 -US20130253197A1,3,COc1ccc(F)c(Cl)c1[C@@H](C)c1c[nH]c2ncc(B3OC(C)(C)C(C)(C)O3)cc12.Cn1cc(Br)c(C(F)(F)F)n1>>COc1ccc(F)c(Cl)c1[C@@H](C)c1c[nH]c2ncc(-c3cn(C)nc3C(F)(F)F)cc12 -US20090176770A1,6,CCOC(=O)CN1CCC(C2CCN(C(=O)[C@@H](Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1>>O=C(O)CN1CCC(C2CCN(C(=O)[C@@H](Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1 -US05256675,1,CC(=O)Nc1ncc(Cl)s1.Cc1nnc(S)s1>>CC(=O)Nc1ncc(Sc2nnc(C)s2)s1 -US09090599B2,2,NCc1nc(C(F)(F)F)no1.O=C(O)c1cnc(O[C@@H]2CCOC2)c(-c2ccc(Cl)cc2)c1>>O=C(NCc1nc(C(F)(F)F)no1)c1cnc(O[C@@H]2CCOC2)c(-c2ccc(Cl)cc2)c1 -US20100278833A1,6,CC(Oc1cc(-n2cnc3cc(CO[Si](C)(C)C(C)(C)C)ncc32)sc1C(N)=O)c1ccccc1C(F)(F)F>>CC(Oc1cc(-n2cnc3cc(CO)ncc32)sc1C(N)=O)c1ccccc1C(F)(F)F -US05153210,1,CC(=O)Cc1ccc(OCc2cc(=O)c(O)co2)cc1.NCC(O)c1ccc(O)cc1>>CC(Cc1ccc(OCc2cc(=O)c(O)co2)cc1)NCC(O)c1ccc(O)cc1 -US20040014968A1,2,CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1C#N.Nc1nccs1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1C#N -US20120101083A1,2,Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(CC(=O)O)C2.OC1CNC1>>Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(CC(=O)N1CC(O)C1)C2 -US20090048427A1,1,O=C1NC(=O)c2ccccc21.OCCCCC1COC(c2ccccc2)O1>>O=C1c2ccccc2C(=O)N1CCCCC1COC(c2ccccc2)O1 -US20090202525A1,9,CCOC(=O)CBr>>CCOC(C)=O -US06043248,2,CC(=O)/C=C/C(=O)Cl.CCNCC>>CCN(CC)C(=O)/C=C/C(C)=O -US20040122057A1,2,COc1ccc(C(OC)C(=O)O)c(Cl)c1.N#Cc1ccc(CN)cc1>>COc1ccc(C(OC)C(=O)NCc2ccc(C#N)cc2)c(Cl)c1 -US20140066432A1,3,CCOC(=O)C1=Cc2cc(Br)ccc2N=C(N)C1.Cc1cccc(B2OC(C)(C)C(C)(C)O2)c1Cl>>CCOC(=O)C1=Cc2cc(-c3cccc(C)c3Cl)ccc2N=C(N)C1 -US20120289522A1,3,CCOC(=O)CC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(O)CC/C=C/c1ccccc1>>CCOC(=O)CC1(c2ccc(-c3ccc(-c4onc(C)c4C(O)CC/C=C/c4ccccc4)cc3)cc2)CC1 -US20110245251A1,9,CCOC(=O)C(C(=O)c1ccccc1)c1cccnc1>>O=C(Cc1cccnc1)c1ccccc1 -US20060084645A1,1,Clc1cc(Cl)nc(Cl)n1.Nc1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(Nc2nc(Cl)cc(Cl)n2)cc1 -US20040157898A1,1,CCO[C@@H](Cc1ccc(O)cc1Cl)C(=O)OC.Cc1oc(C(C)(C)C)nc1CCl>>CCO[C@@H](Cc1ccc(OCc2nc(C(C)(C)C)oc2C)cc1Cl)C(=O)OC -US20050014942A1,6,COC(=O)c1cnc(N2CCN(C(=O)c3c(-c4ccccc4)n(C)c4ccc(C)cc34)CC2)cn1>>Cc1ccc2c(c1)c(C(=O)N1CCN(c3cnc(C(=O)O)cn3)CC1)c(-c1ccccc1)n2C -US20100137276A1,2,FC1(F)CNC1.O=C(O)c1ccc(Br)cc1F>>O=C(c1ccc(Br)cc1F)N1CC(F)(F)C1 -US20060264415A1,2,NCCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1.O=C(Cl)COCc1ccc(F)cc1>>O=C(COCc1ccc(F)cc1)NCCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1 -US20140163025A1,1,CSCCCO.Oc1cc(F)c(Br)cc1F>>CSCCCOc1cc(F)c(Br)cc1F -US20120142633A1,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1.Cc1c(C(=O)O)c2nccc(-c3cc(F)ccc3OCC3CC3)c2n1COCC[Si](C)(C)C>>Cc1c(C(=O)N[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)c2nccc(-c3cc(F)ccc3OCC3CC3)c2n1COCC[Si](C)(C)C -US08765940B2,1,Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)cc(F)c2c1Cl.c1nc2c(cc1N1CCOCC1)NCC21CCOCC1>>Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)cc(F)c2c1N1CC2(CCOCC2)c2ncc(N3CCOCC3)cc21 -US07902248B2,6,CCOC(=O)/C(=N/OC1CCCC1)c1ccc(S(C)(=O)=O)cc1>>CS(=O)(=O)c1ccc(/C(=N\OC2CCCC2)C(=O)O)cc1 -US04309439,2,C#CCC=C(C)C(O)C#C.CC(C)C(C(=O)Cl)c1ccc(Cl)cc1>>C#CCC=C(C)C(C#C)OC(=O)C(c1ccc(Cl)cc1)C(C)C -US20010053851A1,3,C#CCO.COC(=O)C(CC1CCCC1)c1ccc(I)cc1>>COC(=O)C(CC1CCCC1)c1ccc(C#CCO)cc1 -US20100029655A1,3,FC(F)(F)c1ccc(-c2cc(Cn3cc4nc(Br)nc-4cn3)on2)c(C(F)(F)F)c1.OB(O)c1cccc2[nH]ccc12>>FC(F)(F)c1ccc(-c2cc(Cn3cc4nc(-c5cccc6[nH]ccc56)nc-4cn3)on2)c(C(F)(F)F)c1 -US20070232632A1,1,CS(=N)(=O)c1ccc([N+](=O)[O-])cc1.O=C(Cl)N1CCOCC1>>CS(=O)(=NC(=O)N1CCOCC1)c1ccc([N+](=O)[O-])cc1 -US20110319378A1,1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](C=O)CC)C1=O.CN>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CNC)C1=O -US05688798,1,Cc1ncc(CCl)c(N)n1.Clc1ccc(-c2ccc3c(c2)CCNC3)cc1>>Cc1ncc(CN2CCc3cc(-c4ccc(Cl)cc4)ccc3C2)c(N)n1 -US07902203B2,1,CCOC(=O)c1cccnc1Cl.NOCc1ccccc1>>CCOC(=O)c1cccnc1NOCc1ccccc1 -US08022062B2,3,C#CC(C)(C)C.N#Cc1ccc(Br)cc1>>CC(C)(C)C#Cc1ccc(C#N)cc1 -US20110098296A1,1,BrCc1ccccc1.CCOC(=O)c1cccc(O)c1>>CCOC(=O)c1cccc(OCc2ccccc2)c1 -US08101764B2,7,O=C(N[C@@H]1CCN(c2ccc(Br)cn2)C1)C(F)F>>FC(F)CN[C@@H]1CCN(c2ccc(Br)cn2)C1 -US06239151B1,6,CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)CNC(N)=O)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)CNC(N)=O)[C@H](C/C=C/c1ccccc1)C(=O)NO -US06437138B1,6,CC(C)(C)OC(=O)N1CC[C@H]1COc1cnc(Cl)c(Br)c1>>Clc1ncc(OC[C@@H]2CCN2)cc1Br -US06380249B1,1,COCCBr.COc1cc(C=O)cc(Br)c1O>>COCCOc1c(Br)cc(C=O)cc1OC -US20080171743A1,7,COC(=O)c1cc(N2CCOC[C@@H]2C)nc(Cl)n1>>C[C@H]1COCCN1c1cc(CO)nc(Cl)n1 -US20110046134A1,2,O=C(NCC(=O)N1CCNCC1)c1ccc(-c2ccccc2)cc1.O=C(O)c1ccc(Cl)nc1>>O=C(NCC(=O)N1CCN(C(=O)c2ccc(Cl)nc2)CC1)c1ccc(-c2ccccc2)cc1 -US04521625,1,Nc1c(NCCCCl)c(=O)c1=O.Oc1cccc(CN2CCCCC2)c1>>Nc1c(NCCCOc2cccc(CN3CCCCC3)c2)c(=O)c1=O -US20090099106A1,7,O=C(Nc1ccc(Sc2ccnc(O)c2)cc1)c1ccc([N+](=O)[O-])cc1>>Nc1ccc(C(=O)Nc2ccc(Sc3ccnc(O)c3)cc2)cc1 -US20090275574A1,1,O=C1CCC(COCCF)CC1.O=C1CO[C@H]2CCCC[C@@H]2N1C1CCNCC1>>O=C1CO[C@H]2CCCC[C@@H]2N1C1CCN(C2CCC(COCCF)CC2)CC1 -US05672710,6,CCOC(=O)c1cnc(Sc2cc3c(cc2C)C(C)(C)CCC3(C)C)s1>>Cc1cc2c(cc1Sc1ncc(C(=O)O)s1)C(C)(C)CCC2(C)C -US20050065118A1,2,COC(=O)c1cc(O)cc(Oc2cccc(C(F)(F)F)c2)c1.NN>>NNC(=O)c1cc(O)cc(Oc2cccc(C(F)(F)F)c2)c1 -US05618812,1,CC1(C)CCC(=O)CC1.CN>>CNC1CCC(C)(C)CC1 -US20120283260A1,2,COC(=O)c1ccc(CCC(=O)O)cc1.COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccc2n1Cc1ccccn1>>COC(=O)c1ccc(CCC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4Cc3ccccn3)c2Cl)cc1 -US20070203205A1,7,O=Cc1ccc(S(=O)(=O)c2ccccc2)cc1>>O=S(=O)(c1ccccc1)c1ccc(CO)cc1 -US20150175604A1,1,CC(C)N.Cc1cc2c(cc(Cl)c3nnc(C)n32)n1Cc1ccccc1>>Cc1cc2c(cc(NC(C)C)c3nnc(C)n32)n1Cc1ccccc1 -US07211577B2,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(-c2cc(COS(C)(=O)=O)c(=O)n(CC(C)C)n2)ccc1F>>Cc1cc(-c2cc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(=O)n(CC(C)C)n2)ccc1F -US07560569B2,2,CCC(C)c1ccc(N)cc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>CCC(C)c1ccc(NC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)cc1 -US20130030031A1,2,CC(=O)OC(C)=O.COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1cccc(CN)c1>>COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1cccc(CNC(C)=O)c1 -US20070185079A1,1,COc1ccc2c(C)cc(Cl)nc2c1.N[C@H]1C[C@H]2C[C@H](N(Cc3ccccc3)C(=O)OCc3ccccc3)[C@@H]1C2>>COc1ccc2c(C)cc(N[C@H]3C[C@H]4C[C@H](N(Cc5ccccc5)C(=O)OCc5ccccc5)[C@@H]3C4)nc2c1 -US05506256,8,O=C(CCc1ccccc1)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(O)COc1ccccc1>>O=C(COc1ccccc1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CCc1ccccc1 -US07629376B2,1,CCCCc1ccc(N)cc1.NC(=O)c1[nH]c2ccc(C=O)cc2c1Sc1ccccc1>>CCCCc1ccc(NCc2ccc3[nH]c(C(N)=O)c(Sc4ccccc4)c3c2)cc1 -US07951806B2,6,COC(=O)c1cc(Cl)ccc1NC(=O)C(CCC(=O)Nc1ccc(Cl)cc1)NC(=O)OCc1ccccc1>>O=C(CCC(NC(=O)OCc1ccccc1)C(=O)Nc1ccc(Cl)cc1C(=O)O)Nc1ccc(Cl)cc1 -US20110237784A1,3,CC(=O)c1cccc(O)c1.C[Mg+]>>CC(C)(O)c1cccc(O)c1 -US06362181B1,1,C[S-].O=C1c2cccc3c(Br)ccc(c23)C(=O)N1O>>CSc1ccc2c3c(cccc13)C(=O)N(O)C2=O -US04594347,1,CC1Cc2c(N3CCNCC3)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23.CI>>CC1Cc2c(N3CCN(C)CC3)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23 -US04224330,8,Cc1cccc(C(=O)c2ccccc2)n1.O=C(OO)c1cccc(Cl)c1>>Cc1cccc(C(=O)c2ccccc2)[n+]1[O-] -US20090029981A1,1,COCCCBr.COCCCOc1ccc([C@H]2[C@H](O)CN(C(=O)OCc3ccccc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1>>COCCCOc1ccc([C@H]2[C@H](OCCCOC)CN(C(=O)OCc3ccccc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1 -US20040152750A1,6,COC(=O)c1ccc(N(Cc2ccc(OC(F)(F)F)cc2)Cc2ccc(C3CCCCC3)cc2)cc1>>O=C(O)c1ccc(N(Cc2ccc(OC(F)(F)F)cc2)Cc2ccc(C3CCCCC3)cc2)cc1 -US07541365B2,1,CC(C)(O)c1ccc2c(c1)/C(=C/CCBr)c1cccnc1CO2.CCNC(=O)CN(Cc1ccc(Cl)cc1)C1CCNC1>>CCNC(=O)CN(Cc1ccc(Cl)cc1)C1CCN(CCC=C2c3cc(C(C)(C)O)ccc3OCc3ncccc32)C1 -US20090163586A1,3,C#CC1CCCCC1.NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccc(Br)nc1>>NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccc(C#CC2CCCCC2)nc1 -US07547779B2,1,CCn1c(-c2nonc2N)nc2cnc(Br)cc21.CN1CCN(C(=O)CCC(=O)c2cccc(O)c2)CC1>>CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(C(=O)CCC(=O)N4CCN(C)CC4)c3)cc21 -US05430062,7,CCOc1ccc(N=Cc2cc(OC)c(OC)c(OC)c2)cc1>>CCOc1ccc(NCc2cc(OC)c(OC)c(OC)c2)cc1 -US20120289505A1,2,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O.N#Cc1cccc(N=C=S)c1>>COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=S)Nc4cccc(C#N)c4)cc3)cc2C1=O -US20120252801A1,6,CC(C)c1ccc(NC(=O)CC2C(=O)OC(C)(C)CN2Cc2ccccc2)cc1>>CC(C)c1ccc(NC(=O)CC2NCC(C)(C)OC2=O)cc1 -US20120015928A1,1,C1CCNC1.O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccc(F)nc5)cc4)CC3)C2)c2ccccc21>>O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccc(N6CCCC6)nc5)cc4)CC3)C2)c2ccccc21 -US08835427B2,2,CC(C)(C)[Si](C)(C)OCCC(O)CO[Si](C)(C)C(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)OCCC(CO[Si](C)(C)C(C)(C)C)OS(C)(=O)=O -US06307056B1,3,COc1ccccc1B(O)O.O=C1Nc2cccc(I)c2/C1=C/c1ccc[nH]1>>COc1ccccc1-c1cccc2c1/C(=C/c1ccc[nH]1)C(=O)N2 -US20120165310A1,3,CC1(C)OB(c2cccc(OCC3CCCCO3)c2)OC1(C)C.Nc1ncnc2c1c(I)cn2[C@@H]1C[C@H](CO)C1>>Nc1ncnc2c1c(-c1cccc(OCC3CCCCO3)c1)cn2[C@@H]1C[C@H](CO)C1 -US20100056524A1,1,C1COCCN1.O=[N+]([O-])c1cnc(Cl)nc1>>O=[N+]([O-])c1cnc(N2CCOCC2)nc1 -US20110059118A1,2,CCCC(=O)Cl.C[Si](C)(C)CCOCn1ccc2nc(-c3cccnc3N[C@@H]3CCNC3)cnc21>>CCCC(=O)N1CC[C@@H](Nc2ncccc2-c2cnc3c(ccn3COCC[Si](C)(C)C)n2)C1 -US20040141955A1,2,CC(=O)Cl.CCC(C)CO>>CCC(C)COC(C)=O -US20080293696A1,2,CC1(C)OCC(CN)O1.COC(=O)c1cc(CNc2ccccc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)ccn1>>CC1(C)OCC(CNC(=O)c2cc(CNc3ccccc3C(=O)Nc3ccc4c(c3)OC(F)(F)O4)ccn2)O1 -US08450304B2,1,CC(C)(C)[O-].O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(O)(c3ccc(F)nc3)CC2)C1>>CC(C)(C)Oc1ccc(C2(O)CCC(N3CC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cn1 -US05091432,6,CCOC(=O)CCn1cnc2c(=O)[nH]cnc21>>O=C(O)CCn1cnc2c(=O)[nH]cnc21 -US05994378,2,CNC.COC(=O)Cc1cn(Cc2ccc3oc(-c4nc(C(C)(C)C)cs4)cc3c2)c2ccc(OCC(=O)O)cc12>>COC(=O)Cc1cn(Cc2ccc3oc(-c4nc(C(C)(C)C)cs4)cc3c2)c2ccc(OCC(=O)N(C)C)cc12 -US20070249832A1,7,Cc1cccc(S(=O)(=O)NC(C)C)c1[N+](=O)[O-]>>Cc1cccc(S(=O)(=O)NC(C)C)c1N -US20130345120A1,6,CC(C)(C)OC(=O)C1CCN(C(=O)OCc2ccccc2)N1>>O=C(O)C1CCN(C(=O)OCc2ccccc2)N1 -US20070259862A1,6,COC(=O)c1ccc(=O)n(C)c1>>Cn1cc(C(=O)O)ccc1=O -US20060122065A1,1,C#CCOc1ccc(CCC(=O)NCc2ccc(COS(C)(=O)=O)cc2)cc1OC.Oc1ccccc1>>C#CCOc1ccc(CCC(=O)NCc2ccc(COc3ccccc3)cc2)cc1OC -US20020119969A1,2,CSC(=N)N.O=S(=O)(Cl)c1cc(Cl)sc1Cl>>CSC(=N)NS(=O)(=O)c1cc(Cl)sc1Cl -US20080312226A1,2,Nc1ccc(-n2cccn2)cc1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1ccc(-n2cccn2)cc1)OCC(Cl)(Cl)Cl -US20140171313A1,2,CN(C)C(=O)Cl.NCc1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1Cl>>CN(C)C(=O)NCc1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1Cl -US07071173B2,2,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.OCCO>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCCO -US20040186160A1,3,CN(C)C=O.OCCCc1c[nH]c2c1CCCCC2>>O=Cc1[nH]c2c(c1CCCO)CCCCC2 -US20110021487A1,1,CC(C)(C)[Si](C)(C)O[C@@H]1COC[C@H]1Oc1ccc(-c2c(C#N)c(N)nc(S)c2C#N)cc1.ClCc1csc(-c2ccc(Cl)cc2)n1>>CC(C)(C)[Si](C)(C)O[C@@H]1COC[C@H]1Oc1ccc(-c2c(C#N)c(N)nc(SCc3csc(-c4ccc(Cl)cc4)n3)c2C#N)cc1 -US20130274240A1,3,CCOC(=O)c1ccccc1B1OC(C)(C)C(C)(C)O1.Fc1ccc(Br)c(Cl)c1>>CCOC(=O)c1ccccc1-c1ccc(F)cc1Cl -US20020010333A1,6,Cn1c(=O)n(CC(C)(C)O)c(=O)c2c1ncn2Cc1ccccc1>>Cn1c(=O)n(CC(C)(C)O)c(=O)c2[nH]cnc21 -US06136831,8,CC(O)c1nc2ccc(F)cc2o1>>CC(=O)c1nc2ccc(F)cc2o1 -US20130178461A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1-n1ncc2cc(C(C)(C)C)cc(F)c2c1=O.CCS(=O)(=O)c1ccc(Nc2cc(Cl)nn(C)c2=O)nc1>>CCS(=O)(=O)c1ccc(Nc2cc(-c3cccc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3COC(C)=O)nn(C)c2=O)nc1 -US20100160388A1,2,COc1cc(N=C=O)c(Br)cc1C.O=C1C=CNC(c2cccnc2)C1>>COc1cc(NC(=O)N2C=CC(=O)CC2c2cccnc2)c(Br)cc1C -US08183381B2,4,C#CCOc1cccnc1C.CC(C)(C)C(=O)OCN=[N+]=[N-]>>Cc1ncccc1OCc1cnnn1COC(=O)C(C)(C)C -US20150232482A1,3,CC1(C)OB(c2cnn(-c3cccnc3)c2)OC1(C)C.CCON=C1CS(=O)(=O)N(C)c2ccc(Br)nc21>>CCON=C1CS(=O)(=O)N(C)c2ccc(-c3cnn(-c4cccnc4)c3)nc21 -US05760054,1,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1.CI>>Cn1c(=O)n(C2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21 -US08183248B2,2,CCN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1.Cc1ccc(C(=O)Cl)cc1[N+](=O)[O-]>>CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c([N+](=O)[O-])c3)cc2C(F)(F)F)CC1 -US20140161801A1,1,CO.O=[N+]([O-])c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1F>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1[N+](=O)[O-] -US20110071175A1,1,O=Cc1sccc1Br.Sc1ccccc1>>O=Cc1sccc1Sc1ccccc1 -US20050059723A1,3,CN(C)C=O.Cc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1>>Cc1c(C=O)c2ccccc2n1-c1ccc(OCc2ccccc2)cc1 -US20120071474A1,3,CC1(C)OB(c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3)c2)OC1(C)C.Clc1ccc2ncc(Br)n2n1>>O=S(=O)(Nc1cc(-c2cnc3ccc(Cl)nn23)cnc1Cl)c1ccc(F)cc1 -US20110003815A1,3,CC1(C)OB(c2ccc(C3(c4ccc(OCc5nccs5)cc4)CC4CCC3C4)cc2)OC1(C)C.Cc1ccc(Cl)nn1>>Cc1ccc(-c2ccc(C3(c4ccc(OCc5nccs5)cc4)CC4CCC3C4)cc2)nn1 -US20130210795A1,6,COCCOc1ccc(-c2c(C#N)c(N)nc(SC(C)c3cccc(C(=O)OC)c3)c2C#N)cc1>>COCCOc1ccc(-c2c(C#N)c(N)nc(SC(C)c3cccc(C(=O)O)c3)c2C#N)cc1 -US20090042973A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cccc(Br)c1>>CC(C)(C)OC(=O)Nc1cccc(Br)c1 -US04496748,7,C=CCC1CCCCCCCCCCC1=O>>C=CCC1CCCCCCCCCCC1O -US04753922,2,Nc1cccc2ccc(O)cc12.O=CO>>O=CNc1cccc2ccc(O)cc12 -US20060004197A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1cc(F)c([N+](=O)[O-])cc1N>>Cc1ccc(S(=O)(=O)Nc2cc([N+](=O)[O-])c(F)cc2N)cc1 -US20080194561A1,1,NCCO.O=C(CCl)Nc1cccc([N+](=O)[O-])c1>>O=C(CNCCO)Nc1cccc([N+](=O)[O-])c1 -US20130296312A1,1,CN(c1ccccc1CNc1cccn2nc(Cl)nc12)S(C)(=O)=O.Nc1ccc(OCCN2CCCC2)cc1>>CN(c1ccccc1CNc1cccn2nc(Nc3ccc(OCCN4CCCC4)cc3)nc12)S(C)(=O)=O -US08969346B2,6,O=C(NCCNc1n[nH]c2ccc(-c3ccc(NCC4(c5ncccc5F)CCC4)nn3)cc12)OCc1ccccc1>>NCCNc1n[nH]c2ccc(-c3ccc(NCC4(c5ncccc5F)CCC4)nn3)cc12 -US20100144712A1,1,Brc1ccccn1.C1CNCCNC1>>c1ccc(N2CCCNCC2)nc1 -US20040138230A1,1,CC1Cc2cc(CCCCl)ccc2NC1=O.c1ccc2c(N3CCNCC3)n[nH]c2c1>>CC1Cc2cc(CCCN3CCN(c4n[nH]c5ccccc45)CC3)ccc2NC1=O -US20030207896A1,1,Brc1cccc(Br)n1.O=Cc1ccc(OCCO)cc1>>O=Cc1ccc(OCCOc2cccc(Br)n2)cc1 -US07452889B2,9,BrC(Br)(Br)Br.O=C1CC(CO)CN1c1ccc(F)cc1>>O=C1CC(CBr)CN1c1ccc(F)cc1 -US20090181942A1,1,COc1ccc(C=O)c(OC)c1.COc1cccc(C(O)c2cc(Cl)ccc2N)c1OC(F)F>>COc1ccc(CNc2ccc(Cl)cc2C(O)c2cccc(OC)c2OC(F)F)c(OC)c1 -US20060155121A1,2,Nc1c(Cl)cc(Br)cc1Cl.O=C(Cl)CC1CCCC1>>O=C(CC1CCCC1)Nc1c(Cl)cc(Br)cc1Cl -US20100168418A1,1,BrCCOc1ccccc1.CCOC(=O)C1(CCCn2c(=O)ccc3ccc(OC)cc32)CCNCC1>>CCOC(=O)C1(CCCn2c(=O)ccc3ccc(OC)cc32)CCN(CCOc2ccccc2)CC1 -US20100160323A1,2,NCC(=O)N1CCN(C(=O)c2cc(F)ccc2Cl)CC1.O=C(O)c1cn(-c2ccccn2)nn1>>O=C(NCC(=O)N1CCN(C(=O)c2cc(F)ccc2Cl)CC1)c1cn(-c2ccccn2)nn1 -US20150051190A1,7,CC(C)(C)OC(=O)NC1(C(=O)O)CC1>>CC(C)(C)OC(=O)NC1(CO)CC1 -US06992103B2,6,COC(=O)c1cc(C(F)(F)F)cc(N2CCCC2=O)c1F>>O=C(O)c1cc(C(F)(F)F)cc(N2CCCC2=O)c1F -US20080182868A1,9,Clc1nccc2occ(Br)c12.N>>Nc1nccc2occ(Br)c12 -US20100190766A1,6,CC(C)(C)OC(=O)Nc1ncc(C#C[Si](C)(C)C)s1>>C#Cc1cnc(NC(=O)OC(C)(C)C)s1 -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.NC(=O)c1cc(C2CC2)n(-c2cc(I)ccn2)n1>>CN1CC[C@@](O)(C#Cc2ccnc(-n3nc(C(N)=O)cc3C3CC3)c2)C1=O -US07214673B2,1,C=O.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN[C@@H](CCc2ccc(Cl)cc2)C1>>Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)[C@@H](CCc2ccc(Cl)cc2)C1 -US20060154929A1,8,CCOc1ccc(-n2c(C)c3c(C)nnc(C)c3c2C)cc1CO>>CCOc1ccc(-n2c(C)c3c(C)nnc(C)c3c2C)cc1C=O -US20060270706A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=Cc1nc[nH]n1>>CC(C)(C)OC(=O)n1cnc(C=O)n1 -US06815460B2,7,CNS(=O)(=O)c1ccc([N+](=O)[O-])cc1>>CNS(=O)(=O)c1ccc(N)cc1 -US20100240702A1,6,COC(=O)C(C)(C)Cn1c(=O)n(Cc2csc3cccc(C)c23)c2ccccc21>>Cc1cccc2scc(Cn3c(=O)n(CC(C)(C)C(=O)O)c4ccccc43)c12 -US20090186907A1,1,CC(C)=O.Nn1c(-c2c(F)cccc2F)c(Cl)nc(-n2cccn2)c1=O>>CC(C)=Nn1c(-c2c(F)cccc2F)c(Cl)nc(-n2cccn2)c1=O -US07858640B2,4,CCC(=O)C(Cc1ccc(C(=O)N2CCCC2)cc1)C(=O)OC.COC(=O)COc1ccc(Cl)c(N)c1>>CCc1[nH]c2c(Cl)ccc(OCC(=O)OC)c2c(=O)c1Cc1ccc(C(=O)N2CCCC2)cc1 -US07179819B2,8,CC(C)(C)OC(=O)N1CC(F)(F)CC1CO>>CC(C)(C)OC(=O)N1CC(F)(F)CC1C=O -US05498609,6,COC(=O)c1ccc(NC(=O)c2ccccc2C)nc1>>Cc1ccccc1C(=O)Nc1ccc(C(=O)O)cn1 -US20150057260A1,3,CCOC(=O)c1cc(Cl)cc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1.Cn1nccc1B(O)O>>CCOC(=O)c1cc(-c2ccnn2C)cc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1 -US07115750B1,1,CC(=O)Nc1ccc2c(c1)CCCC2=O.CI>>CC(=O)N(C)c1ccc2c(c1)CCCC2=O -US07893099B2,1,COC(=O)[C@H]1C[C@H](S(=O)(=O)c2ccccc2Cl)C[C@@H]1O.Cc1ccc(CBr)cc1>>COC(=O)[C@H]1C[C@H](S(=O)(=O)c2ccccc2Cl)C[C@@H]1OCc1ccc(C)cc1 -US04025630,1,C=CCN1CCC2=C(C1)c1c(O)cc(C(C)C(C)CCCCC)cc1OC2(CC)CC.O=C(O)CCCN1CCCCC1>>C=CCN1CCC2=C(C1)c1c(OC(=O)CCCN3CCCCC3)cc(C(C)C(C)CCCCC)cc1OC2(CC)CC -US08217032B2,2,CS(=O)(=O)Cl.O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(OS(=O)(=O)C(F)(F)F)ccc2cc(O)ccc12>>CS(=O)(=O)Oc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(OS(=O)(=O)C(F)(F)F)ccc2c1 -US20090270500A1,2,CN(C)C[C@H](N)CC(=O)OCc1ccccc1.O=C(O)CCCCCCCOCc1ccc(F)cc1F>>CN(C)C[C@@H](CC(=O)OCc1ccccc1)NC(=O)CCCCCCCOCc1ccc(F)cc1F -US20090221555A1,1,COCCN1CCc2ccc(N)cc2CC1.N#CCOc1cccc(F)c1Nc1nc(Cl)ncc1Cl>>COCCN1CCc2ccc(Nc3ncc(Cl)c(Nc4c(F)cccc4OCC#N)n3)cc2CC1 -US20100041891A1,6,CCOC(=O)c1cccc(-c2cccn3nc(Nc4cccc(C(F)(F)F)c4)nc23)c1>>O=C(O)c1cccc(-c2cccn3nc(Nc4cccc(C(F)(F)F)c4)nc23)c1 -US07326792B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSC1=N[C@@H]2CCCC[C@@H]2N1>>CSC1=N[C@@H]2CCCC[C@@H]2N1C(=O)OC(C)(C)C -US20070208005A1,6,CCOC(=O)c1cncn1Cc1ccc2c(c1)CCN(C(=O)OC(C)(C)C)CC2>>CC(C)(C)OC(=O)N1CCc2ccc(Cn3cncc3C(=O)O)cc2CC1 -US20060211698A1,6,COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CC(=O)OC(C)(C)C)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CC(=O)O)c2c1 -US20150252008A1,1,CC(C)(C)c1cc(Cl)nc(N)n1.Nc1cnc(-c2ccc(C3CCC3)c(O)c2F)cn1>>CC(C)(C)c1cc(Oc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)nc(N)n1 -US20100234346A1,9,CC(=O)c1cc(C)nc(NC(C)C)n1.NO>>CC(=NO)c1cc(C)nc(NC(C)C)n1 -US20120122931A1,7,O=C(O)c1ccc2cc(-c3ccccc3)[nH]c2c1>>OCc1ccc2cc(-c3ccccc3)[nH]c2c1 -US06362211B1,3,O=C(Cl)C1CCCCC1.c1ccccc1>>O=C(c1ccccc1)C1CCCCC1 -US06992085B2,2,Nc1ccc(Cl)cc1.O=C(O)CCCN1CCN2CCCCC2C1>>O=C(CCCN1CCN2CCCCC2C1)Nc1ccc(Cl)cc1 -US20140309220A1,6,COC(=O)c1ccc(O[C@@H]2CCOC2)c(OC)c1>>COc1cc(C(=O)O)ccc1O[C@@H]1CCOC1 -US07179823B1,8,OCc1cn(Cc2ccc(OCc3ccccc3)cc2)nc1OCc1ccc(OCc2ccccc2)cc1>>O=Cc1cn(Cc2ccc(OCc3ccccc3)cc2)nc1OCc1ccc(OCc2ccccc2)cc1 -US20060241127A1,1,Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1.Nc1nc(Cl)cc(C2CCCN(C(=O)OCc3ccccc3)C2)n1>>Nc1nc(Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)cc(C2CCCN(C(=O)OCc3ccccc3)C2)n1 -US08680108B2,1,CC(=O)c1cc(Cl)c2cccnc2c1OS(=O)(=O)C(F)(F)F.COC1CCNC1>>COC1CCN(c2c(C(C)=O)cc(Cl)c3cccnc23)C1 -US20090181942A1,6,COC(=O)CCc1cnc(C[C@@H]2S[C@@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c(CF)nnc32)s1>>COc1cccc([C@@H]2S[C@@H](Cc3ncc(CCC(=O)O)s3)c3nnc(CF)n3-c3ccc(Cl)cc32)c1OC -US05716936,6,CC(C)(C)OC(=O)C1CC(S(C)(=O)=O)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1>>CC(C)(C)OC(=O)C1CC(S(C)(=O)=O)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)O)c1 -US20150239920A1,1,CC(=O)c1cn(CC(=O)OC(C)(C)C)c2ccc(O)cc12.Fc1ncc(Br)cn1>>CC(=O)c1cn(CC(=O)OC(C)(C)C)c2ccc(Oc3ncc(Br)cn3)cc12 -US20040122016A1,6,COC(=O)Cc1cccc(OCCCl)c1>>O=C(O)Cc1cccc(OCCCl)c1 -US05746840,1,CC(C)(C)OC(=O)NN.Cn1nnc2ccc(C(=O)c3ccc(Cl)cc3)cc21>>Cn1nnc2ccc(C(=NNC(=O)OC(C)(C)C)c3ccc(Cl)cc3)cc21 -US20140288062A1,6,CN(C(=O)OC(C)(C)C)c1ccc2c(c1[N+](=O)[O-])OCCO2>>CNc1ccc2c(c1[N+](=O)[O-])OCCO2 -US20130331372A1,3,CSc1ncc(Br)c(CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)n1.Nc1cc(B(O)O)ccc1F>>CSc1ncc(-c2ccc(F)c(N)c2)c(CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)n1 -US20030176454A1,1,Cc1ncc(-c2cc(N)cc(Cl)c2)n1C.Clc1ncnc2c1CCc1ccccc1-2>>Cc1ncc(-c2cc(Cl)cc(Nc3ncnc4c3CCc3ccccc3-4)c2)n1C -US20070185156A1,6,COc1ccc(COc2cccc(Oc3ccccc3)c2C)cc1>>Cc1c(O)cccc1Oc1ccccc1 -US08710232B2,2,Nc1ccc(CC(C(=O)O)c2cn(C3CCCCC3)cn2)cn1.OCCO>>Nc1ccc(CC(C(=O)OCCO)c2cn(C3CCCCC3)cn2)cn1 -US08580968B2,1,C1CCNCC1.CS(=O)(=O)OC1CN(c2nc3ccc(Br)cc3s2)C1>>Brc1ccc2nc(N3CC(N4CCCCC4)C3)sc2c1 -US08426448B2,1,CC(C)(N)c1cccc(C(F)(F)F)n1.COc1cccc([C@H]2CC(=O)C(=O)N2c2ccc(C(F)(F)F)cc2)c1>>COc1cccc([C@H]2C[C@@H](NC(C)(C)c3cccc(C(F)(F)F)n3)C(=O)N2c2ccc(C(F)(F)F)cc2)c1 -US06090804,2,Nc1nnc(-c2ccc(CN3CCCCCC3)s2)o1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)Nc1nnc(-c2ccc(CN3CCCCCC3)s2)o1 -US07067534B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3cccc(F)c3)CC2)c1.NNc1cccc2ccccc12>>CC(C)C(=O)Nc1cccc(C2CCN(CCCc3c(-c4cccc(F)c4)[nH]c4c3ccc3ccccc34)CC2)c1 -US20110319426A1,3,COc1ncc(C2(c3cccc(Br)c3)N=C(N)c3c(F)cccc32)cc1C(F)(F)F.OB(O)c1cncnc1>>COc1ncc(C2(c3cccc(-c4cncnc4)c3)N=C(N)c3c(F)cccc32)cc1C(F)(F)F -US20050038035A1,2,Cc1ccc(C(=O)O)c(-c2ccc(C(F)(F)F)cc2)c1.Cc1ccc(C)n1-c1cccc(CCCOc2ccc(N)cc2)n1>>Cc1ccc(C(=O)Nc2ccc(OCCCc3cccc(-n4c(C)ccc4C)n3)cc2)c(-c2ccc(C(F)(F)F)cc2)c1 -US20100035899A1,1,CC(C)C[C@H](CO)Nc1nc(S)nc2nc(N)sc12.C[C@@H](Cl)c1cc(C#N)ccn1>>CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2cc(C#N)ccn2)nc2nc(N)sc12 -US20140336381A1,6,CC(C)(C)OC(=O)N1CCN(c2cc(-c3ccc(Cl)s3)c(C(F)(F)F)nn2)CC1>>FC(F)(F)c1nnc(N2CCNCC2)cc1-c1ccc(Cl)s1 -US20100256097A1,1,CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(N)s2)c(F)c1.CNC(=O)OCc1nccc(Cl)n1>>CNC(=O)OCc1nccc(Nc2sc(-c3c(F)cc(C(C)(C)O)cc3F)cc2C(N)=O)n1 -US05663337,6,COC(=O)Cc1ccccc1>>O=C(O)Cc1ccccc1 -US07326791B2,2,C1CSCN1.C[C@H](NC(=O)c1ccc(C(=O)O)c(Br)c1)c1nc2cc(Cl)ccc2[nH]1>>C[C@H](NC(=O)c1ccc(C(=O)N2CCSC2)c(Br)c1)c1nc2cc(Cl)ccc2[nH]1 -US07087606B2,1,CNC.Cc1ccc(-c2cc(COS(C)(=O)=O)c(=O)n(CC(C)C)n2)cc1>>Cc1ccc(-c2cc(CN(C)C)c(=O)n(CC(C)C)n2)cc1 -US20100152219A1,1,Clc1ncc(Cl)c(Cl)n1.Nc1cc(OCC2CC2)[nH]n1>>Clc1ncc(Cl)c(Nc2cc(OCC3CC3)[nH]n2)n1 -US20140249126A1,7,CCn1nc(C(=O)O)c(=O)c2c([N+](=O)[O-])c3c(cc21)OCO3>>CCn1nc(C(=O)O)c(=O)c2c(N)c3c(cc21)OCO3 -US20110110889A1,3,CC(=O)Cl.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]ccc3c2)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]cc(C(C)=O)c3c2)c1F -US20100256092A1,1,O=Cc1ccc(F)cc1Br.Oc1ccccc1>>O=Cc1ccc(Oc2ccccc2)cc1Br -US20120283260A1,2,CNC(=O)[C@H]1CCCN(CC(=O)O)C1.COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccc2n1Cc1ccccn1>>CNC(=O)[C@H]1CCCN(CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4Cc3ccccn3)c2Cl)C1 -US04330549,1,Cc1cc(=O)n(C)c2cc(O)ccc12.O=C(NC1CCN(CCCCl)CC1)c1ccccc1>>Cc1cc(=O)n(C)c2cc(OCCCN3CCC(NC(=O)c4ccccc4)CC3)ccc12 -US06252084B1,6,CCc1c(CC(N)=O)c2cc(OCc3ccccc3C(=O)OC)ccc2n1Cc1ccccc1>>CCc1c(CC(N)=O)c2cc(OCc3ccccc3C(=O)O)ccc2n1Cc1ccccc1 -US07285563B2,9,Clc1cc2ccccc2c(Cl)n1>>Clc1cc2ccccc2cn1 -US20010006969A1,1,CC(C)(C)CN.Cc1csc2c(Cl)nc(Cl)nc12>>Cc1csc2c(NCC(C)(C)C)nc(Cl)nc12 -US20070032518A1,4,CCc1cc(C(N)=S)ccn1.COC(=O)CC(=O)CCl>>CCc1cc(-c2nc(CC(=O)OC)cs2)ccn1 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)[C@@H]1C[C@H]1c1ccc(F)cc1F>>CC(C)C[C@H]1CN(C(=O)[C@@H]2C[C@H]2c2ccc(F)cc2F)[C@@H](CC(C)C)C(=O)N1 -US20080255172A1,1,Cc1cc2cc(O)ccc2[nH]1.Clc1ccnc(Cl)n1>>Cc1cc2cc(Oc3ccnc(Cl)n3)ccc2[nH]1 -US20040266826A1,1,CCCI.C[Si](C)(C)CCOC(=O)C[C@]1(c2ccc(-c3ccc(O)cc3)s2)CCCCS1(=O)=O>>CCCOc1ccc(-c2ccc([C@@]3(CC(=O)OCC[Si](C)(C)C)CCCCS3(=O)=O)s2)cc1 -US20100273770A1,1,CC(C)(C)OC(=O)NCCO.CCOC(=O)/C=C/c1cccc(Br)c1O>>CCOC(=O)/C=C/c1cccc(Br)c1OCCNC(=O)OC(C)(C)C -US20130040930A1,2,C[C@H](NS(C)(=O)=O)c1ccc(C(=O)O)cc1.Cc1cnc(N2CCNCC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc([C@H](C)NS(C)(=O)=O)cc3)CC2)c(C)c1 -US20100035918A1,2,CC(N)C(O[Si](C)(C)C(C)(C)C)c1ccc2ncnn2c1.Cc1cccc(N=C=O)c1>>Cc1cccc(NC(=O)NC(C)C(O[Si](C)(C)C(C)(C)C)c2ccc3ncnn3c2)c1 -US20090215778A1,7,CC(=O)c1ccccn1>>C[C@@H](O)c1ccccn1 -US20100216802A1,7,CC(C)(C)OC(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)OC1CCCC1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)OC1CCCC1 -US20070203218A1,1,CI.CS(=O)(=O)Nc1cccc(Br)c1>>CN(c1cccc(Br)c1)S(C)(=O)=O -US20090281139A1,2,CC(=O)N(CC(=O)O)Cc1ccc(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)C(=O)NCc2cccc(N)c2)cc1>>CC(=O)N1CC(=O)Nc2cccc(c2)CNC(=O)C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)c2ccc(cc2)C1 -US20150014671A1,3,Brc1ccc(I)cc1.Cc1ccnc(Br)c1>>Cc1ccnc(-c2ccc(Br)cc2)c1 -US20060014945A1,1,CC1(C)CCNC(=O)[C@H](NS(=O)(=O)c2ccc(Cl)cc2)C1.COC(=O)c1ccc(CBr)c(F)c1>>COC(=O)c1ccc(CN([C@@H]2CC(C)(C)CCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)c(F)c1 -US04997836,1,CCI.COc1cc(C(=O)N2CCN(Cc3ccccc3)C(CO)C2)cc(OC)c1OC>>CCOCC1CN(C(=O)c2cc(OC)c(OC)c(OC)c2)CCN1Cc1ccccc1 -US06706878B2,1,CI.Oc1ncccc1Br>>COc1ncccc1Br -US20110269753A1,6,CCOC(=O)c1cccc(-c2csc(-c3ccc(OC)c4oc5ccccc5c34)n2)n1>>COc1ccc(-c2nc(-c3cccc(C(=O)O)n3)cs2)c2c1oc1ccccc12 -US20140243306A1,2,CS(=O)(=O)Cl.Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1ncnc2[nH]c(C3=CCNCC3)cc12>>Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1ncnc2[nH]c(C3=CCN(S(C)(=O)=O)CC3)cc12 -US20130150325A1,1,CS(=O)(=O)OCc1cccc(C(=O)N2CCCC2)c1.Cc1cc(/C=C(\F)c2ccc(OC(F)(F)F)cc2)n[nH]1>>Cc1cc(/C=C(\F)c2ccc(OC(F)(F)F)cc2)nn1Cc1cccc(C(=O)N2CCCC2)c1 -US20090018122A1,1,NCC1CCOCC1.O=[N+]([O-])c1cnc2ccc(OCc3ccccc3)cc2c1Cl>>O=[N+]([O-])c1cnc2ccc(OCc3ccccc3)cc2c1NCC1CCOCC1 -US20140336377A1,2,C[C@@H](N)c1cccc(C(F)(F)F)c1.Nc1nccc(C(=O)O)n1>>C[C@@H](NC(=O)c1ccnc(N)n1)c1cccc(C(F)(F)F)c1 -US20150038528A1,6,C[C@@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)[C@H](C)C(=O)OC(C)(C)C>>C[C@@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)[C@H](C)C(=O)O -US20140243544A1,1,CC(C)C(=O)[O-].CC(Cl)OC(=O)Oc1c(F)cccc1F>>CC(OC(=O)Oc1c(F)cccc1F)OC(=O)C(C)C -US07964591B2,2,CC(C)CCNC(=O)c1ccc(N2CCNCC2)nn1.O=C(O)c1cnccc1C(F)(F)F>>CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3cnccc3C(F)(F)F)CC2)nn1 -US07208495B2,6,Cc1c(C)c(N2CCN(C(=O)OC(C)(C)C)CC2)c(C)c2c1OC(C)(C)C2N1CCCCC1>>Cc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)(C)C2N1CCCCC1 -US20090176847A1,1,COC1CC2CC(OS(C)(=O)=O)CC2C1.[N-]=[N+]=[N-]>>COC1CC2CC(N=[N+]=[N-])CC2C1 -US07638551B2,1,C#CCO.Cc1ccc(O)cc1C>>C#CCOc1ccc(C)c(C)c1 -US20130338134A1,1,COc1cc(OC)c(F)c(N)c1F.COc1ccc(Cn2ncc3c(Cl)c(CCl)cnc32)cc1>>COc1ccc(Cn2ncc3c(Cl)c(CNc4c(F)c(OC)cc(OC)c4F)cnc32)cc1 -US20060148858A1,6,COC(=O)Cc1cn(C2CCCCC2)nc1OCc1ccccc1>>COC(=O)Cc1cn(C2CCCCC2)nc1O -US08828987B2,2,COC(=O)c1ccc(C2(N)CC2)cc1.O=C(O)c1cc(C(F)(F)F)cnc1N1CC(Oc2cccc(F)c2)C1>>COC(=O)c1ccc(C2(NC(=O)c3cc(C(F)(F)F)cnc3N3CC(Oc4cccc(F)c4)C3)CC2)cc1 -US20100190764A1,6,COC(=O)C1=CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1>>O=C(O)C1=CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1 -US20130252941A1,8,Fc1cc(Cl)c(-n2cc3cncc(F)c3n2)c(Cl)c1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1cc(F)c2nn(-c3c(Cl)cc(F)cc3Cl)cc2c1 -US20090264431A1,6,CC(C)(C)OC(=O)N1C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@@H]1COCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@@H](O)C[C@@H]1COCc1ccccc1 -US06987116B2,1,CN1CCNCC1.COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(C=O)cc4)sc23)c(Cl)cc1Cl>>COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCN(C)CC5)cc4)sc23)c(Cl)cc1Cl -US20060211866A1,6,CCCc1nc2c(C)cc(-c3nc4ccccc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CCCc1nc2c(C)cc(-c3nc4ccccc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20150038534A1,2,CC(C)(CN)c1nc(-c2cc(F)cc(F)c2)cs1.O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1>>CC(C)(CNC(=O)c1cccc(-c2noc(C(F)(F)F)n2)c1)c1nc(-c2cc(F)cc(F)c2)cs1 -US09090599B2,2,C[C@H](Oc1cnc(C(=O)O)nc1-c1ccc(Cl)cc1)C(F)(F)F.NCc1cc(C(F)(F)F)no1>>C[C@H](Oc1cnc(C(=O)NCc2cc(C(F)(F)F)no2)nc1-c1ccc(Cl)cc1)C(F)(F)F -US06852863B2,2,CC(C)(C)OC(=O)COc1cccc(CN)c1.O=S(=O)(Cl)c1cccnc1>>CC(C)(C)OC(=O)COc1cccc(CNS(=O)(=O)c2cccnc2)c1 -US04294843,1,CN(C)c1ccccc1S.NC(CCl)=NO>>CN(C)c1ccccc1SCC(N)=NO -US20110082202A1,2,CC(C)(C)OC(=O)NCCOCCN.CC1(c2ccccc2)OC(C(=O)O)=CC1=O>>CC(C)(C)OC(=O)NCCOCCNC(=O)C1=CC(=O)C(C)(c2ccccc2)O1 -US04839355,3,CCOC(=O)c1cn2c3c(c(Br)c(F)c(F)c3c1=O)OC[C@@H]2C.Cc1cc([Sn](C)(C)C)cc(C)n1>>CCOC(=O)c1cn2c3c(c(-c4cc(C)nc(C)c4)c(F)c(F)c3c1=O)OC[C@@H]2C -US08324216B2,1,COc1cc(N2CCN(C(=O)CCl)CC2)ccc1Cl.Fc1ccccc1-c1[nH]nc(C(F)(F)F)c1Cl>>COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3-c3ccccc3F)CC2)ccc1Cl -US03970704,8,CC(C)=CCCC(C)CC(C)O>>CC(=O)CC(C)CCC=C(C)C -US20080113963A1,1,CC(N)=O.Cc1nc2c(OCc3ccccc3)cc(Br)cc2n1C>>CC(=O)Nc1cc(OCc2ccccc2)c2nc(C)n(C)c2c1 -US20110301142A1,6,CCOC(=O)c1csc(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)n1>>Cc1noc(-c2ccc(-c3nc(C(=O)O)cs3)cc2)c1NC(=O)OC(C)c1ccccc1Cl -US20150197527A1,2,CCCn1c2ccccc2c2nc(SCC(=O)O)n(-c3ccccc3)c(=O)c21.NC1CCCCC1>>CCCn1c2ccccc2c2nc(SCC(=O)NC3CCCCC3)n(-c3ccccc3)c(=O)c21 -US04599296,2,CCCCCCC(O)CCCCCCCCCCC(=O)OC.CCCCN>>CCCCCCC(O)CCCCCCCCCCC(=O)NCCCC -US04187213,1,CC1(C)CC(OCCBr)CC(C)(C)N1.Oc1ccc(-c2nc3ccccc3o2)cc1>>CC1(C)CC(OCCOc2ccc(-c3nc4ccccc4o3)cc2)CC(C)(C)N1 -US20030207927A1,3,CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COCOc1cccc(C=O)c1>>CC=Cc1cccc(OCOC)c1 -US20150119362A1,8,OCCc1ccc(Nc2nc(-c3cccc(Cl)c3)nc3c2CCC3)cc1>>O=CCc1ccc(Nc2nc(-c3cccc(Cl)c3)nc3c2CCC3)cc1 -US08217043B2,1,CC(C)(C)OC(=O)Nn1cccc1.FC(F)(F)c1ccc(CCl)cc1>>CC(C)(C)OC(=O)N(Cc1ccc(C(F)(F)F)cc1)n1cccc1 -US20050032786A1,8,CSc1cncc(-c2nc(=O)c3ccccc3s2)n1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cncc(-c2nc(=O)c3ccccc3s2)n1 -US08344135B2,6,COc1cc([N+](=O)[O-])ccc1C#N>>N#Cc1ccc([N+](=O)[O-])cc1O -US20110251247A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1cc(Br)ccc1F>>CC(C)(C)OC(=O)NCc1cc(Br)ccc1F -US20080045493A1,2,CCCN1CC[C@@H](c2ccc(N)cc2)C1.O=S(=O)(F)c1ccc(SC(F)(F)F)cc1>>CCCN1CC[C@@H](c2ccc(NS(=O)(=O)c3ccc(SC(F)(F)F)cc3)cc2)C1 -US04283221,1,COCC=O.Cc1cccc(C)c1N>>COCC=Nc1c(C)cccc1C -US05413997,1,NC1CCCCCCC1.O=Cc1ccccc1C(c1ccc(OCc2ccccc2)cc1)c1ccc(OCc2ccccc2)cc1>>c1ccc(COc2ccc(C(c3ccc(OCc4ccccc4)cc3)c3ccccc3CNC3CCCCCCC3)cc2)cc1 -US20060111362A1,1,CC#CCn1c(=O)n(C)c2ccnc(Cl)c21.CC(C)(C)OC(=O)N1CCNCC1>>CC#CCn1c(=O)n(C)c2ccnc(N3CCN(C(=O)OC(C)(C)C)CC3)c21 -US20090082399A1,2,O=C(c1ccc(F)cc1)N1CCC[C@H](O)C1.O=C=Nc1cccc(F)c1>>O=C(Nc1cccc(F)c1)O[C@H]1CCCN(C(=O)c2ccc(F)cc2)C1 -US07279470B2,2,O=C(Cl)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1.O=C1CCCN1C1CCNCC1>>O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(N2CCCC2=O)CC1 -US05153203,6,CCOC(=O)c1cn(C2CC2)c2c(F)c(N3CCOC3)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2c(F)c(N3CCOC3)c(F)cc2c1=O -US20110152318A1,1,CC(NC(=O)c1coc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1.CC(c1cccc(O)c1)C(F)(F)F>>CC(NC(=O)c1coc(Oc2cccc(C(C)C(F)(F)F)c2)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1 -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1cc(OC2CCOCC2)cc(C)c1Br>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OC6CCOCC6)cc5C)ccc(F)c43)ccc21 -US08129396B2,7,NC(=O)C(=C1Nc2ccc([N+](=O)[O-])cc2S1)c1nccc(C(F)(F)F)n1>>NC(=O)C(=C1Nc2ccc(N)cc2S1)c1nccc(C(F)(F)F)n1 -US20150133479A1,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.O=c1cc(O)cc[nH]1>>CC(C)(C)OC(=O)N1CCC(Oc2cc[nH]c(=O)c2)CC1 -US07557127B2,6,CCOC(=O)/C=C/c1csc(NC2CCN(C(=O)c3ccc(Cl)cc3)C2)n1>>O=C(O)/C=C/c1csc(NC2CCN(C(=O)c3ccc(Cl)cc3)C2)n1 -US20060041014A1,2,Cc1nnc(N)s1.O=C(OCc1ccccc1)C(CCc1ccccc1)CC1(C(=O)O)CCCC1>>Cc1nnc(NC(=O)C2(CC(CCc3ccccc3)C(=O)OCc3ccccc3)CCCC2)s1 -US08604038B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc(C[C@@H]2CC[C@H]([C@H](O[Si](C)(C)C(C)(C)C)c3ccccc3)N2)cc1>>COC(=O)c1ccc(C[C@@H]2CC[C@H]([C@H](O[Si](C)(C)C(C)(C)C)c3ccccc3)N2C(=O)OC(C)(C)C)cc1 -US20140296226A1,3,CC1(C)OB(C2=CCCOC2)OC1(C)C.NC1=N[C@@]2(CCO1)c1cc(N)ccc1Oc1c2cc(Cl)nc1F>>NC1=N[C@@]2(CCO1)c1cc(N)ccc1Oc1c2cc(C2=CCCOC2)nc1F -US20150210640A1,1,COC(=O)[C@@H]1[C@@H](O)CCN1C(=O)OC(C)(C)C.O=C(O)c1ccccc1>>COC(=O)[C@@H]1[C@H](OC(=O)c2ccccc2)CCN1C(=O)OC(C)(C)C -US08999993B2,1,CNCCOC.Nc1cc(Cl)ccc1[N+](=O)[O-]>>COCCN(C)c1ccc([N+](=O)[O-])c(N)c1 -US20140343032A1,6,CCOC(=O)COC1CC2COCC(C1)N2C(=O)OCc1ccccc1>>CCOC(=O)COC1CC2COCC(C1)N2 -US06087399,2,CS(=O)(=O)Cl.NC1CCCc2ccc([N+](=O)[O-])cc21>>CS(=O)(=O)NC1CCCc2ccc([N+](=O)[O-])cc21 -US20140364412A1,1,CC(C)(C)c1cc(N)n(-c2ccc(Cl)c(O)c2)n1.OCCOC1CCCCO1>>CC(C)(C)c1cc(N)n(-c2ccc(Cl)c(OCCOC3CCCCO3)c2)n1 -US06051712,10,CCCC1CN(C)CC=C1c1ccc(Cl)cc1.O>>CCCC1CN(C)CC(O)C1c1ccc(Cl)cc1 -US20130029962A1,2,CN(CCO)Cc1ccc(N)cn1.O=C(Cl)Oc1ccccc1>>CN(CCO)Cc1ccc(NC(=O)Oc2ccccc2)cn1 -US20100113418A1,2,CC(=O)Cl.Cc1c(C(=O)OCc2ccccc2)sc(N)c1C(=O)OC(C)(C)C>>CC(=O)Nc1sc(C(=O)OCc2ccccc2)c(C)c1C(=O)OC(C)(C)C -US08048909B2,2,Cc1c(C=O)c[nH]c1-c1ccccc1.O=S(=O)(Cl)c1cccc2c1OCCO2>>Cc1c(C=O)cn(S(=O)(=O)c2cccc3c2OCCO3)c1-c1ccccc1 -US20090029947A1,7,COCCCCC#Cc1ccc([C@@H]2CC[C@](N)(C(=O)OC)C2)cc1>>COCCCCCCc1ccc([C@@H]2CC[C@](N)(C(=O)OC)C2)cc1 -US08722702B2,6,COC(=O)c1cc(NC(=O)OCc2ccccc2)nn1C>>COC(=O)c1cc(N)nn1C -US20100056527A1,2,CC(C)(C)OC(=O)N1CCC(CN)CC1.Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(-c3ccccc3Cl)oc12>>Cc1cc(C(=O)NCC2CCN(C(=O)OC(C)(C)C)CC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3Cl)oc12 -US06858638B2,2,Nc1ccc2[nH]nc(I)c2c1.O=S(=O)(Cl)c1cccc(F)c1>>O=S(=O)(Nc1ccc2[nH]nc(I)c2c1)c1cccc(F)c1 -US08188113B2,3,CCOC(=O)c1cnc(C(C)(C)C)nc1Cl.OB(O)c1cccc(F)c1>>CCOC(=O)c1cnc(C(C)(C)C)nc1-c1cccc(F)c1 -US07572805B2,1,CC(C)(C)OC(=O)N1C[C@H]2NC(=O)c3c(cccc3C(F)(F)F)[C@@H]2C1.CI>>CN1C(=O)c2c(cccc2C(F)(F)F)[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]21 -US20140323535A1,6,CCCCCCc1c(C(=O)c2cccc(C(=O)OC)c2)c2cc(Cl)ccc2n1C>>CCCCCCc1c(C(=O)c2cccc(C(=O)O)c2)c2cc(Cl)ccc2n1C -US20110065725A1,2,CCOC(=O)c1nnn(-c2ccc(F)c(Cl)c2)c1C.Nc1ccnc(Cl)c1>>Cc1c(C(=O)Nc2ccnc(Cl)c2)nnn1-c1ccc(F)c(Cl)c1 -US20130109682A1,3,COC(=O)c1ccc(F)c(Br)n1.O=Cc1ccc(F)c(B(O)O)c1F>>COC(=O)c1ccc(F)c(-c2c(F)ccc(C=O)c2F)n1 -US20130324518A1,2,COC(=O)CCC(C(N)=O)N1Cc2cccc(OC(=O)c3ccc(CN4CCN(C(=O)OC(C)(C)C)CC4)cc3)c2C1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(C(=O)Oc3cccc4c3CN(C3CCC(=O)NC3=O)C4)cc2)CC1 -US04609652,2,CCN1CCN(C(=O)Cl)C(=O)C1=O.C[C@H](OCc1ccccc1)[C@@H](N)C(=O)O>>CCN1CCN(C(=O)N[C@@H](C(=O)O)[C@H](C)OCc2ccccc2)C(=O)C1=O -US06933305B2,2,Nc1ccncc1.O=C(NC1CCOc2cc(C(=O)O)ccc21)OCc1ccccc1>>O=C(NC1CCOc2cc(C(=O)Nc3ccncc3)ccc21)OCc1ccccc1 -US20130012485A1,3,C=CCC(C#N)(CC=C)c1cccc(C)c1>>Cc1cccc(C2(C#N)CC=CC2)c1 -US20150246922A1,3,Cc1c2n(c3c(Br)cc(C#N)cc13)CCCNC2=O.OB(O)c1ccc(Cl)cc1>>Cc1c2n(c3c(-c4ccc(Cl)cc4)cc(C#N)cc13)CCCNC2=O -US06444672B1,6,CCOC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccc2c(N)nccc2c1)C(C)(C)SCC(=O)OC(C)(C)C>>CCOC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccc2c(N)nccc2c1)C(C)(C)SCC(=O)O -US07582773B2,1,BrCc1ccccc1.Brc1ccc2[nH]c3c(c2c1)CCCC3>>Brc1ccc2c(c1)c1c(n2Cc2ccccc2)CCCC1 -US20110245249A1,5,CC(=O)c1ccc(Nc2ncc(Cl)c(NC3CC3)n2)cc1.OCCO>>CC1(c2ccc(Nc3ncc(Cl)c(NC4CC4)n3)cc2)OCCO1 -US20150133425A1,2,CCOc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)O)C3.CNCCOC>>CCOc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)N(C)CCOC)C3 -US20120040936A1,1,CC(C)OCCO.CC1(C)OB(c2ccc(O)cc2)OC1(C)C>>CC(C)OCCOc1ccc(B2OC(C)(C)C(C)(C)O2)cc1 -US08222281B2,7,CS(=O)(=O)c1cccc(C(=O)O)c1>>CS(=O)(=O)c1cccc(CO)c1 -US20030208050A1,9,Cc1cn([C@H]2C[C@H](O)[C@@H](CN=[N+]=[N-])O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CN)O2)c(=O)[nH]c1=O -US20140155389A1,3,CON(C)C(=O)c1cc(Cl)nc(Cl)c1.C[Mg+]>>CC(=O)c1cc(Cl)nc(Cl)c1 -US20070225349A1,6,C=CCn1nc(-c2ccc(OC)cc2C)c2cccc(C(F)(F)F)c21>>C=CCn1nc(-c2ccc(O)cc2C)c2cccc(C(F)(F)F)c21 -US20080262011A1,3,CCCCCCC(C)(C)c1ccc(Br)c(O)c1.OB(O)c1cc(Cl)cc(Cl)c1>>CCCCCCC(C)(C)c1ccc(-c2cc(Cl)cc(Cl)c2)c(O)c1 -US20070249670A1,6,COC(=O)[C@](C)(NC(=O)c1ccc(F)cc1NC(=O)Nc1c(C)cc(C)cc1C)C1CCCCC1>>Cc1cc(C)c(NC(=O)Nc2cc(F)ccc2C(=O)N[C@@](C)(C(=O)O)C2CCCCC2)c(C)c1 -US20120053180A1,2,CCc1cnc(OC2CCC(C(=O)O)CC2)nc1.CS(=O)(=O)N1CCN(C(=O)CCCN)CC1>>CCc1cnc(OC2CCC(C(=O)NCCCC(=O)N3CCN(S(C)(=O)=O)CC3)CC2)nc1 -US08501746B2,2,Cc1nc(-n2ccc(OCc3ccccc3)cc2=O)sc1C(=O)O.NCc1ccc(C(F)(F)F)nc1>>Cc1nc(-n2ccc(OCc3ccccc3)cc2=O)sc1C(=O)NCc1ccc(C(F)(F)F)nc1 -US07148234B2,1,Nc1ccc(CCO)cc1.O=[N+]([O-])c1cc(Cl)c(Cl)nc1Cl>>O=[N+]([O-])c1cc(Cl)c(Cl)nc1Nc1ccc(CCO)cc1 -US05510531,7,CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1Cl)C(=O)OC>>CCCC[C@@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1Cl -US20070259881A1,1,C1CNCCN1.CC(C)Cn1c(CCl)nc2c(N)nc3ccccc3c21>>CC(C)Cn1c(CN2CCNCC2)nc2c(N)nc3ccccc3c21 -US20130331382A1,3,CC1(C)OB(Cc2ccccc2)OC1(C)C.Cn1nc(-c2ccccc2OS(=O)(=O)C(F)(F)F)ccc1=O>>Cn1nc(-c2ccccc2Cc2ccccc2)ccc1=O -US20080027112A1,1,COc1ccc2c(Cl)cc(=O)oc2c1OC1CCCC1.Nc1c(Cl)cccc1C(F)(F)F>>COc1ccc2c(Nc3c(Cl)cccc3C(F)(F)F)cc(=O)oc2c1OC1CCCC1 -US20100041892A1,2,CCCCCS(N)(=O)=O.N#CCCCOc1ccc(/C=C/C(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1>>CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCCC#N)cc1Oc1ncc(C(F)(F)F)cc1Cl -US04551272,2,CCOC(=O)[C@@H](N)Cc1ccccc1.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)OCc1ccccc1 -US20080261941A1,1,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccc(O)cc3)c2)CC1.FC(F)(F)CI>>CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccc(OCC(F)(F)F)cc3)c2)CC1 -US08859768B2,6,CCOC(=O)c1cc(-c2cc(NC(C)=O)ncc2C)oc1Br>>CC(=O)Nc1cc(-c2cc(C(=O)O)c(Br)o2)c(C)cn1 -US08138168B1,6,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCCC(c2nc3ccccc3[nH]2)C1)Cc1ccc(Cl)cc1>>N[C@@H](CC(=O)N1CCCC(c2nc3ccccc3[nH]2)C1)Cc1ccc(Cl)cc1 -US06399604B1,1,CN.N#Cc1ccc(CBr)cc1>>CNCc1ccc(C#N)cc1 -US20070225332A1,6,COc1ccc(Oc2ncc(-c3cc(C(C)N4C(=O)c5ccccc5C4=O)on3)s2)c(Cl)c1>>COc1ccc(Oc2ncc(-c3cc(C(C)N)on3)s2)c(Cl)c1 -US04697033,1,CCC(C)Oc1ccc(O)cc1.COC(=O)NCCCl>>CCC(C)Oc1ccc(OCCNC(=O)OC)cc1 -US20140371201A1,1,CCOC(=O)/C=C/c1cc(Br)c(F)cc1N.SCc1ccccc1>>CCOC(=O)/C=C/c1cc(SCc2ccccc2)c(F)cc1N -US06951848B2,1,C1CCNC1.Cc1[nH]c2ccc(CCOS(C)(=O)=O)cc2c1C(=O)OCc1ccccc1>>Cc1[nH]c2ccc(CCN3CCCC3)cc2c1C(=O)OCc1ccccc1 -US08952004B2,2,CN1CCCNCC1.O=C(O)CC1CCN(c2ncc(-c3ccccc3)cc2NC(=O)c2cccc(Cl)c2)CC1>>CN1CCCN(C(=O)CC2CCN(c3ncc(-c4ccccc4)cc3NC(=O)c3cccc(Cl)c3)CC2)CC1 -US20020035266A1,3,COC(=O)/C(I)=C\C1CCCC1.Cc1nnnn1-c1ccc(I)cc1Cl>>COC(=O)/C(=C/C1CCCC1)c1ccc(-n2nnnc2C)c(Cl)c1 -US04894386,2,COC(=O)c1ccc2[nH]ccc2c1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1ccc2c(ccn2S(=O)(=O)c2ccc(C)cc2)c1 -US05366982,6,COc1cc(-c2ccccc2)cc(-c2ccccc2)c1>>Oc1cc(-c2ccccc2)cc(-c2ccccc2)c1 -US07713964B2,7,COC(=O)c1ccc(OCCc2c(C=CC(=O)O)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1>>COC(=O)c1ccc(OCCc2c(CCC(=O)O)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 -US08153644B2,1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1cc([N+](=O)[O-])ccc1F>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2C#N)CC1 -US08048909B2,1,C[NH3+].O=Cc1cc(-c2ccc(F)cc2)n(S(=O)(=O)c2ccc(C(F)(F)F)cc2)c1>>CNCc1cc(-c2ccc(F)cc2)n(S(=O)(=O)c2ccc(C(F)(F)F)cc2)c1 -US08901141B2,8,CCN(CC)c1cccc2nc(C(O)c3ccc(Cl)cc3Cl)n(CCCO)c12>>CCN(CC)c1cccc2nc(C(=O)c3ccc(Cl)cc3Cl)n(CCCO)c12 -US06958145B2,3,CCCCC(C)=O.O=CC(=O)O>>CCCC(=CC(=O)O)C(C)=O -US20120015957A1,1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1ccc(F)c(F)c1>>CC(C)(C)OC(=O)N1CCN(c2ccc(C#N)cc2F)CC1 -US20070032530A1,1,FC(F)(F)c1ccc(-c2cncc(CCl)c2)cc1.Oc1ccc(CCCCn2ccnn2)cc1>>FC(F)(F)c1ccc(-c2cncc(COc3ccc(CCCCn4ccnn4)cc3)c2)cc1 -US20110295004A1,1,CCOC(=O)CCCCCCBr.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1O>>CCOC(=O)CCCCCCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC -US20060235037A1,3,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)C1.COc1ccccc1-c1cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2[nH]1>>COc1ccccc1-c1cc2cc(C3=CCN(C(=O)OC(C)(C)C)CC3(C)C)ccc2[nH]1 -US20100048537A1,1,CN1CCc2sccc2C(O)C1.Fc1cccc(Br)c1Cl>>CN1CCc2sccc2C(Oc2cccc(Br)c2Cl)C1 -US20070213331A1,2,CCCNC.O=C(O)c1cncc(C(=O)O)c1>>CCCN(C)C(=O)c1cncc(C(=O)O)c1 -US20100317607A1,1,C1CCNC1.Clc1nc(NCc2ccccc2)c2ccccc2n1>>c1ccc(CNc2nc(N3CCCC3)nc3ccccc23)cc1 -US20030171592A1,7,O=[N+]([O-])CC(O)c1ccc(F)cc1>>NCC(O)c1ccc(F)cc1 -US08497264B2,3,NC1=N[C@@]2(COC1)c1cc(Br)ccc1Oc1ccc(I)cc12.OB(O)c1ccnc(F)c1>>NC1=N[C@@]2(COC1)c1cc(Br)ccc1Oc1ccc(-c3ccnc(F)c3)cc12 -US20150119396A9,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.O=C1CCC2(CC1)OCCO2>>CC(C)(C)OC(=O)N[C@@H]1CCN(C2CCC3(CC2)OCCO3)C1 -US08283361B2,1,CCOC(=O)c1cn(CC2CCNC2)c2ccc(I)cc2c1=O.ClCC1CCCO1>>CCOC(=O)c1cn(CC2CCN(CC3CCCO3)C2)c2ccc(I)cc2c1=O -US08933105B2,2,CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc(OCc2ccccc2)cc1>>CN(Cc1cn(S(=O)(=O)c2ccc(OCc3ccccc3)cc2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C -US20090258917A1,6,COc1cccc(Cl)c1N>>Nc1c(O)cccc1Cl -US20100317657A1,1,CCNc1cc(-c2ccc3ncc4c(c3c2)n(-c2cn(C)nc2C)c(=O)n4C)cnc1CO.CI>>CCNc1cc(-c2ccc3ncc4c(c3c2)n(-c2cn(C)nc2C)c(=O)n4C)cnc1COC -US08324176B2,6,COC(=O)CCNS(=O)(=O)c1ccccc1[N+](=O)[O-]>>O=C(O)CCNS(=O)(=O)c1ccccc1[N+](=O)[O-] -US06489479B1,2,NC(=O)C[C@H](N)C(=O)O.O=C(O)c1ccc2ccccc2n1>>NC(=O)C[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)O -US06313137B1,1,Cc1ccccc1CCl.Cc1nc2c(N)cc(C(N)=O)cn2c1C>>Cc1ccccc1CNc1cc(C(N)=O)cn2c(C)c(C)nc12 -US20090298836A1,3,CC(C)=O.N[C@H](CNc1nnc(-c2ccc3c(c2)CC(=O)N3)s1)Cc1ccc(C(F)(F)F)cc1>>CC(C)=C1C(=O)Nc2ccc(-c3nnc(NC[C@@H](N)Cc4ccc(C(F)(F)F)cc4)s3)cc21 -US20140206673A1,1,CC(C)[C@@H]1CNCCN1.CC1(C)Cc2c(C#N)c(OS(=O)(=O)C(F)(F)F)nc(C3CC3)c2CO1>>CC(C)[C@@H]1CN(c2nc(C3CC3)c3c(c2C#N)CC(C)(C)OC3)CCN1 -US04587360,2,COc1cc(N)cc(OC)c1.O=S(=O)(Cl)CCCCl>>COc1cc(NS(=O)(=O)CCCCl)cc(OC)c1 -US08003783B2,3,COc1cc(C=O)cc(OC)c1OC.C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O>>COc1cc(C=C2CC3C4CCc5cc(O)ccc5C4CCC3(C)C2=O)cc(OC)c1OC -US05288701,7,CC(=O)C(C)C=CC1CCC(C)C1(C)C>>CC(O)C(C)C=CC1CCC(C)C1(C)C -US20120184561A1,1,CCOC(=O)Cc1ccc(N)cc1.O=[N+]([O-])c1c(Cl)ncnc1Cl>>CCOC(=O)Cc1ccc(Nc2ncnc(Cl)c2[N+](=O)[O-])cc1 -US20080227781A1,2,CC(C)(CNCC(F)(F)F)n1cnc(N)c1.CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)O>>CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(C(C)(C)CNCC(F)(F)F)cn1 -US05889010,7,O=[N+]([O-])c1cc(F)ccc1NCCCO>>Nc1cc(F)ccc1NCCCO -US04073921,2,CCCCCCCCC(C#N)(CO)c1ccc(Cl)cc1Cl.CS(=O)(=O)Cl>>CCCCCCCCC(C#N)(COS(C)(=O)=O)c1ccc(Cl)cc1Cl -US06794395B1,2,Nc1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN2CCCCC2)cc1)c1ccccc1.O=C(O)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN2CCCCC2)cc1)c1ccccc1 -US20040209859A1,6,CCOC(=O)C1C2CCC(C(C)(C)C)CC21>>CC(C)(C)C1CCC2C(C1)C2C(=O)O -US08541457B2,2,CCC(N)c1ccccc1.Cc1nc(NC(=O)c2ccccc2)sc1C(=O)O>>CCC(NC(=O)c1sc(NC(=O)c2ccccc2)nc1C)c1ccccc1 -US20070129416A1,2,CC(=O)N1CCNCC1.CCOc1cc(C(F)(F)F)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl>>CCOc1cc(C(F)(F)F)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(C(C)=O)CC1 -US20120232070A1,6,CC(C)(C)OC(=O)N(N)C(=O)c1ccc(Cc2cc3cc(C(F)(F)F)ccc3n2S(=O)(=O)c2cccc(C(C)(C)C)c2)cc1>>CC(C)(C)c1cccc(S(=O)(=O)n2c(Cc3ccc(C(=O)NN)cc3)cc3cc(C(F)(F)F)ccc32)c1 -US20090163586A1,2,Nc1ccccc1S(N)(=O)=O.O=S(=O)(Cl)c1cccc(Cl)c1F>>NS(=O)(=O)c1ccccc1NS(=O)(=O)c1cccc(Cl)c1F -US20050054631A1,1,C1CNCCN1.CCOc1cccc(-n2c(Cl)c(C=O)c3ccccc32)c1>>CCOc1cccc(-n2c(N3CCNCC3)c(C=O)c3ccccc32)c1 -US06248755B1,3,C=C[Mg+].O=CC1CCN(C(=O)c2ccccc2)CC1>>C=CC(O)C1CCN(C(=O)c2ccccc2)CC1 -US03952001,1,C=CCN(CC=C)S(=O)(=O)c1nc[nH]n1.CCN(CC)C(=O)Cl>>C=CCN(CC=C)S(=O)(=O)c1ncn(C(=O)N(CC)CC)n1 -US20090221555A1,1,ClCCCBr.O=c1[nH]c2cc([N+](=O)[O-])ccc2o1>>O=c1oc2ccc([N+](=O)[O-])cc2n1CCCCl -US09150557B1,1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O.OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCl>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OCCCN1CC(O)C(O)[C@H](O)C1CO -US20130261132A1,2,COc1cc([C@@H](C)N[C@H]2CC[C@@H](c3ccc(OCC(=O)O)cc3)C2)ccc1F.OCCN1CCNCC1>>COc1cc([C@@H](C)N[C@H]2CC[C@@H](c3ccc(OCC(=O)N4CCN(CCO)CC4)cc3)C2)ccc1F -US20130261122A1,3,O=C(O)c1ccc(B(O)O)c(F)c1.Oc1ccc2cc(Br)ccc2c1F>>O=C(O)c1ccc(-c2ccc3c(F)c(O)ccc3c2)c(F)c1 -US07332497B2,1,CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1.Nc1ncnc2[nH]nc(I)c12>>CC(C)(C)OC(=O)N1CC(n2nc(I)c3c(N)ncnc32)C1 -US20080306082A1,1,CN1CCN(CCCN)CC1.Cc1cnc(Cl)nc1-c1cc2ccc(NC(=O)OC(C)(C)C)cc2s1>>Cc1cnc(NCCCN2CCN(C)CC2)nc1-c1cc2ccc(NC(=O)OC(C)(C)C)cc2s1 -US20100022591A1,6,COC(=O)c1ccc(OCCCC2CCN(C(=O)OC(C)(C)C)CC2)cc1F>>COC(=O)c1ccc(OCCCC2CCNCC2)cc1F -US05624948,9,BrC(Br)(Br)Br.COC(=O)C(C)(C)Cc1ccc(CCO)cc1>>COC(=O)C(C)(C)Cc1ccc(CCBr)cc1 -US05142061,4,CC(=O)OO.COC(=O)C1=C(Cc2ccc(Cl)cc2)CCC1(C)C>>COC(=O)C12OC1(Cc1ccc(Cl)cc1)CCC2(C)C -US04619924,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=S1CCCC(O)C1>>Cc1ccc(S(=O)(=O)OC2CCCS(=O)C2)cc1 -US20150057271A1,2,COc1ccc(CNc2nccs2)cc1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1F>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc([N+](=O)[O-])c(F)c2)cc1 -US20060094767A1,4,CC(C)(C)OC(=O)N1CCN(CC(=O)N2CCC(=O)CC2)CC1.C[S+](C)(C)=O>>CC(C)(C)OC(=O)N1CCN(CC(=O)N2CCC3(CC2)CO3)CC1 -US07355069B2,1,COC(=O)c1ccccc1CBr.O=C(O)CCc1ccc(S)cc1>>COC(=O)c1ccccc1CSc1ccc(CCC(=O)O)cc1 -US20080306116A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.Fc1ccc(-c2cnc(Cl)o2)cc1>>CC(C)(C)OC(=O)N1CCC(Nc2ncc(-c3ccc(F)cc3)o2)CC1 -US07582761B2,3,O=c1[nH]c2cc(C(F)(F)F)cc(Br)c2[nH]1.OB(O)c1cc(F)c(F)c(F)c1>>O=c1[nH]c2cc(C(F)(F)F)cc(-c3cc(F)c(F)c(F)c3)c2[nH]1 -US08008298B2,2,COc1cc(-c2cnc3[nH]cc(I)c3n2)cc(OC)c1OC.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc(-c2cnc3c(n2)c(I)cn3S(=O)(=O)c2ccc(C)cc2)cc(OC)c1OC -US08053447B2,1,CCOC(=O)C1CCC(O)CC1.O=C(NC1C2CC3CC(C2)CC1C3)c1ccc(O)cc1>>CCOC(=O)C1CCC(Oc2ccc(C(=O)NC3C4CC5CC(C4)CC3C5)cc2)CC1 -US04439609,7,CN(C)Cc1ccnc(CCCC#N)c1>>CN(C)Cc1ccnc(CCCCN)c1 -US20100137313A1,1,COc1nc(Cl)ncc1Br.Cc1cc(C)cc(N)c1>>COc1nc(Nc2cc(C)cc(C)c2)ncc1Br -US08614209B2,3,COC(=O)c1csc(Br)c1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>COC(=O)c1csc(-c2ccnn2C)c1 -US20070149562A1,1,COC(=O)c1cc(F)ccc1N.O=C1CCC2(CC1)OCCO2>>COC(=O)c1cc(F)ccc1NC1CCC2(CC1)OCCO2 -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)Nc4ccc(Oc5ccccc5)cc4)cc3)cc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NC(=O)Nc4ccc(Oc5ccccc5)cc4)cc3)cc2C1=O -US20090192336A1,1,OCCCBr.Oc1ccc(OCC=C(Cl)Cl)cc1>>OCCCOc1ccc(OCC=C(Cl)Cl)cc1 -US20130274475A1,2,Nc1ccncc1.O=C(O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>O=C(Nc1ccncc1)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1 -US20130281428A1,3,CC1(C)OB(c2ccc(N)cc2F)OC1(C)C.Nc1ncc(Br)cc1I>>Nc1ccc(-c2cc(Br)cnc2N)c(F)c1 -US05849735,2,O=C(Cl)c1ccc(C(=O)c2ccccc2)cc1.c1ccc2c(c1)CNc1ccccc1O2>>O=C(c1ccccc1)c1ccc(C(=O)N2Cc3ccccc3Oc3ccccc32)cc1 -US05364871,9,CC(=O)OCc1cccc(C(N)=O)n1>>CC(=O)OCc1cccc(C#N)n1 -US06762205B1,6,COc1ccc(CN(C)C(=O)c2ccc(C#N)cc2)cc1>>CN(Cc1ccc(O)cc1)C(=O)c1ccc(C#N)cc1 -US06730672B2,2,CC1CN(S(=O)(=O)c2ccc3ccccc3c2)C(C)CN1.O=C(Cl)C1CCN(c2ccncc2)CC1>>CC1CN(S(=O)(=O)c2ccc3ccccc3c2)C(C)CN1C(=O)C1CCN(c2ccncc2)CC1 -US20090018134A1,2,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C3CCOC3)CC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C3CCOC3)CC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US07572808B2,1,CCN.O=c1n(Cc2ccc(C(F)(F)F)nc2Cl)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn12>>CCNc1nc(C(F)(F)F)ccc1Cn1nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn2c1=O -US06906084B2,6,CCOC(=O)c1cc2ccccc2n1CCc1ccc(Cl)cc1>>O=C(O)c1cc2ccccc2n1CCc1ccc(Cl)cc1 -US04251444,2,CC(CSC(=O)c1ccccc1)C(=O)Cl.O=C(O)C1Cc2ccccc2CN1>>CC(CSC(=O)c1ccccc1)C(=O)N1Cc2ccccc2CC1C(=O)O -US20150133438A1,4,CC(=O)NNC(=O)[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1>>Cc1nnc([C@H]2C[C@H]3CSC(NC(=O)c4ccccc4)=N[C@@]3(c3ccc(F)cc3F)CO2)o1 -US07781591B2,3,CCCC[Sn](CCCC)(CCCC)c1cc2cc(C=O)ccc2o1.Cc1c(Nc2c(I)cncc2C#N)cc(Cl)c2[nH]ccc12>>Cc1c(Nc2c(C#N)cncc2-c2cc3cc(C=O)ccc3o2)cc(Cl)c2[nH]ccc12 -US05885990,1,CN(C)N=CNc1ccc(C(=O)O)cc1.N=C(N)c1ccc2c(CC(N)=O)c(O)ccc2c1>>CN(C)N=CNc1ccc(C(=O)Oc2ccc3cc(C(=N)N)ccc3c2CC(N)=O)cc1 -US20120245176A1,6,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc([N+](=O)[O-])cc1Cl>>C[C@@H]1CNCCN1c1ccc([N+](=O)[O-])cc1Cl -US20140179690A1,6,O=C(NC1=N[C@@]2(c3cccc(F)c3F)CO[C@H](CF)[C@H]2CS1)c1ccccc1>>NC1=N[C@@]2(c3cccc(F)c3F)CO[C@H](CF)[C@H]2CS1 -US05837715,6,CC(C)(C)OC(=O)N1CC[C@@H](NCc2ccccc2C(F)(F)F)[C@H](F)C1>>F[C@@H]1CNCC[C@H]1NCc1ccccc1C(F)(F)F -US20100324010A1,6,COCCCNc1nc(C(C)(C)C)ncc1C(=O)N(CC(C)C)[C@H]1C[C@@H](C(=O)N2CCN(C)CC2)CN(C(=O)OC(C)(C)C)C1>>COCCCNc1nc(C(C)(C)C)ncc1C(=O)N(CC(C)C)[C@@H]1CNC[C@H](C(=O)N2CCN(C)CC2)C1 -US20100121048A1,1,C1COCCN1.COC(=O)c1cnn(-c2cccc(Br)c2)c1C1CCCCC1>>COC(=O)c1cnn(-c2cccc(N3CCOCC3)c2)c1C1CCCCC1 -US20090149445A1,2,CN(C)S(=O)(=O)Cl.Nc1cccc(C=C2c3ccccc3CCc3ccccc32)c1>>CN(C)S(=O)(=O)Nc1cccc(C=C2c3ccccc3CCc3ccccc32)c1 -US20080207695A1,6,CCn1cccc(CNN2CCC(C)=C(CC(=O)NCc3c(C)cc(NC(=O)OC(C)(C)C)nc3CO)C2=O)c1=O>>CCn1cccc(CNN2CCC(C)=C(CC(=O)NCc3c(C)cc(N)nc3CO)C2=O)c1=O -US20120289500A1,2,CCOC(=O)c1nn(N)c(=O)c2ccccc12.O=C(Cl)Cc1ccc(Cl)cc1>>CCOC(=O)c1nn(NC(=O)Cc2ccc(Cl)cc2)c(=O)c2ccccc12 -US20130225810A1,9,COC(=O)c1ccc(C#N)c([N+](=O)[O-])c1.N>>N#Cc1ccc(C(N)=O)cc1[N+](=O)[O-] -US05153214,6,CCOC(=O)CCC(CCCCN(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Cl)cc1)CCOc1cccnc1>>CCOC(=O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCOc1cccnc1 -US08222248B2,6,COC(=O)c1ccc2cc(-c3c(Cl)cccc3Cl)[nH]c2c1>>O=C(O)c1ccc2cc(-c3c(Cl)cccc3Cl)[nH]c2c1 -US03979390,1,O=C(c1ccccc1)C(F)CC(F)N1CCC(O)(c2ccc(Cl)cc2)CC1.OC1(c2ccc(Cl)cc2)CCNCC1>>O=C(c1ccccc1)C(F)CC(N1CCC(O)(c2ccc(Cl)cc2)CC1)N1CCC(O)(c2ccc(Cl)cc2)CC1 -US08202856B2,1,O=Cc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1.OCC1CCNCC1>>OCC1CCN(Cc2ccc(-c3noc(-c4nnn(-c5ccccc5F)c4-c4ccncc4)n3)cc2)CC1 -US06727264B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](NC(=O)c3cc(Cl)cc(Cl)c3)c3ccccc3)CC2)c1 -US08546376B2,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(ccc5nc(C(F)F)[nH]c54)c3=O)cc2)CCC1>>NC1(c2ccc(-c3c(-c4ccccc4)oc4c(ccc5nc(C(F)F)[nH]c54)c3=O)cc2)CCC1 -US09096524B2,2,CC(C)COc1ccc(N2CCN(CCC(=O)O)CC2)cc1.O=[N+]([O-])c1ccc(NC2CCNCC2)cc1C(F)(F)F>>CC(C)COc1ccc(N2CCN(CCC(=O)N3CCC(Nc4ccc([N+](=O)[O-])c(C(F)(F)F)c4)CC3)CC2)cc1 -US20120115842A1,2,COc1ccccc1C1(CN[C@@H](C)C(=O)N(C)C)C(=O)Nc2ccc(C#N)cc21.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>COc1ccccc1C1(CN[C@@H](C)C(=O)N(C)C)C(=O)N(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)c2ccc(C#N)cc21 -US20140088053A1,7,C[C@]12CC[C@@H]3c4ccc(B(O)O)cc4CC[C@H]3[C@@H]1C/C(=C\c1cccc(C(N)=O)c1)C2=O>>C[C@]12CC[C@@H]3c4ccc(B(O)O)cc4CC[C@H]3[C@@H]1C/C(=C\c1cccc(C(N)=O)c1)[C@@H]2O -US06956037B2,1,Cc1ccc(NC(=O)c2cccc(N(C)C)c2)cc1NC(=O)c1ccccc1F.NCCCN1CCOCC1>>Cc1ccc(NC(=O)c2cccc(N(C)C)c2)cc1NC(=O)c1ccccc1NCCCN1CCOCC1 -US07790727B2,7,CC(C)(C)OC(=O)N1CCN(c2cc([N+](=O)[O-])ccc2OC(F)(F)F)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(N)ccc2OC(F)(F)F)CC1 -US04971975,9,O=C(CBr)C12CCCN(CC1)C2.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(=O)C12CCCN(CC1)C2 -US04593034,2,COc1ccc(C(=O)Cl)c(OC)c1.NC1CN2CCC1CC2>>COc1ccc(C(=O)NC2CN3CCC2CC3)c(OC)c1 -US20130225637A1,9,O=C1Nc2c(F)cccc2C1=O>>O=C1Nc2ccccc2C1=O -US20120157479A1,5,C=CCNCC=C.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCN(CC=C)C(=O)OC(C)(C)C -US20150225394A1,2,CNC.O=C(O)CC1(N2CCC(N[C@@H]3C[C@H]3c3ccccc3)CC2)CCC1>>CN(C)C(=O)CC1(N2CCC(N[C@@H]3C[C@H]3c3ccccc3)CC2)CCC1 -US07285543B2,2,CCOP(=O)(CN)OCC.COC(=O)c1nc2c(N)ncnc2n1CCc1ccccc1>>CCOP(=O)(CNC(=O)c1nc2c(N)ncnc2n1CCc1ccccc1)OCC -US07465808B2,1,C=CCN.CCOC(=O)C(Cc1cc(-c2ccc(Br)cc2)n(-c2ccc(C)cc2)n1)c1cccc(C)c1>>C=CCNc1ccc(-c2cc(CC(C(=O)OCC)c3cccc(C)c3)nn2-c2ccc(C)cc2)cc1 -US20140364414A1,3,CC(C)(C)OC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.O=Cc1cn2c(Br)cnc(N3CCOCC3)c2n1>>CC(C)(C)OC(=O)c1ccc(-c2cnc(N3CCOCC3)c3nc(C=O)cn23)cc1 -US05929094,7,COC(=O)C1CCC2(C=C(c3nc(-n4nnnc4C(F)(F)F)ccc3OC)CO2)C1c1ccc(F)cc1>>COC(=O)[C@H]1CC[C@@]2(C[C@@H](c3nc(-n4nnnc4C(F)(F)F)ccc3OC)CO2)[C@@H]1c1ccc(F)cc1 -US20130165422A1,6,CC(C)(C)OC(=O)N1CCC(Cn2cc(C(N)=O)cn2)CC1>>NC(=O)c1cnn(CC2CCNCC2)c1 -US20150225399A1,2,CC(C)OCCN.CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCCC2=O)c1=O>>CC(C)OCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCCC2=O)c1=O -US20130053381A1,1,CC(C)COC(=O)Cl.CS(=O)(=O)Nn1c(=O)[nH]c2cc(C(F)(F)F)c([C@H]3CCCO3)cc2c1=O>>CC(C)COC(=O)N(n1c(=O)[nH]c2cc(C(F)(F)F)c([C@H]3CCCO3)cc2c1=O)S(C)(=O)=O -US08044211B2,1,ClCCCCCBr.Nc1c(C(=O)c2ccc(F)cc2F)ccc(=O)n1-c1c(F)cc(O)cc1F>>Nc1c(C(=O)c2ccc(F)cc2F)ccc(=O)n1-c1c(F)cc(OCCCCCCl)cc1F -US20150197493A1,1,C=CCC(O)CCl.C=CCN>>C=CCNCC(O)CC=C -US06093731,9,O=C(Cl)C=Cc1ccc(Br)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC(=O)C=Cc1ccc(Br)cc1 -US07423030B2,1,CCCCc1nnc(Cl)c2cc(OC)ccc12.NC1CCN(Cc2ccc3ccccc3c2)CC1>>CCCCc1nnc(NC2CCN(Cc3ccc4ccccc4c3)CC2)c2cc(OC)ccc12 -US20140329797A1,2,C1CN(C2CC2)CCN1.O=C(Cl)c1cccc(Cn2nc(-c3nc(-c4ccc(OC(F)(F)F)cc4)no3)ccc2=O)c1>>O=C(c1cccc(Cn2nc(-c3nc(-c4ccc(OC(F)(F)F)cc4)no3)ccc2=O)c1)N1CCN(C2CC2)CC1 -US20070015761A1,9,CC1(C)CC(O)C(=O)c2ccccc21.NO>>CC1(C)CC(O)C(=NO)c2ccccc21 -US05008263,1,COCCO.Cn1nc(CBr)c([N+](=O)[O-])c1Cl>>COCCOCc1nn(C)c(Cl)c1[N+](=O)[O-] -US05444084,8,OCCOCCOc1cccc(-c2ccsc2)c1>>O=CCOCCOc1cccc(-c2ccsc2)c1 -US20100216813A1,2,CC(=O)Nc1ccc(S(=O)(=O)Cl)c(C)c1.N#Cc1ccc(N(Cc2ccccc2Cl)[C@H]2CCNC2)cc1Cl>>CC(=O)Nc1ccc(S(=O)(=O)N2CC[C@H](N(Cc3ccccc3Cl)c3ccc(C#N)c(Cl)c3)C2)c(C)c1 -US08563547B2,1,FC(F)(F)COCCOc1ccc(OC2CCNCC2)cc1.O=C(CCl)N[C@@H]1COc2nc([N+](=O)[O-])cn2C1>>O=C(CN1CCC(Oc2ccc(OCCOCC(F)(F)F)cc2)CC1)N[C@@H]1COc2nc([N+](=O)[O-])cn2C1 -US20130023534A1,6,COc1cc([N+](=O)[O-])cc(S(C)(=O)=O)c1>>CS(=O)(=O)c1cc(O)cc([N+](=O)[O-])c1 -US20070142333A1,1,Clc1nc(Cl)c2ccccc2n1.NCC1(c2ccccc2)CCCCC1>>Clc1nc(NCC2(c3ccccc3)CCCCC2)c2ccccc2n1 -US04562207,6,CCCC[C@H]1CC[C@@H](O)[C@@H]1COCc1ccccc1>>CCCC[C@H]1CC[C@@H](O)[C@@H]1CO -US06156914,1,CCN(CC)c1cccc(O)c1.COC(=O)CCl>>CCN(CC)c1cccc(OCC(=O)OC)c1 -US06413974B1,1,CCCCCCN.Clc1nc(Cl)c2ncn(C3CCCC3)c2n1>>CCCCCCNc1nc(Cl)nc2c1ncn2C1CCCC1 -US07012080B2,1,CC(C)(O)CN1CCC(CN(Cc2ccccc2)Cc2ccccc2)CC1.CI>>COC(C)(C)CN1CCC(CN(Cc2ccccc2)Cc2ccccc2)CC1 -US04992433,6,CC1(C)COC(c2ccc(OCCCC3CCN(Cc4ccccc4)CC3)cc2)=N1>>CC1(C)COC(c2ccc(OCCCC3CCNCC3)cc2)=N1 -US06518273B1,1,FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1.O=C(CCc1c(-c2ccc(Cl)cc2)[nH]c2ccc(Cl)cc12)N1CCNCC1>>O=C(CCc1c(-c2ccc(Cl)cc2)[nH]c2ccc(Cl)cc12)N1CCN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US20060025414A1,2,Cc1cc(C(=O)O)cc(Cl)n1.NN>>Cc1cc(C(=O)NN)cc(Cl)n1 -US20120208810A1,1,C1COCCN1.O=c1c(F)c(Cl)nc2n1CC[C@@H](C(F)(F)F)N2>>O=c1c(F)c(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2 -US20090181942A1,3,CN(C)C=O.COc1ccc(F)c(C(=O)c2cc(Cl)ccc2-n2cccc2)c1OC>>COc1ccc(F)c(C(=O)c2cc(Cl)ccc2-n2cccc2C=O)c1OC -US20090111800A1,6,Cc1cc(OCc2ccccc2)cc(C)c1C[C@@H]1CCN(C2CCc3n[nH]cc3C2)C1=O>>Cc1cc(O)cc(C)c1C[C@@H]1CCN(C2CCc3n[nH]cc3C2)C1=O -US08003648B2,6,COC(=O)C[C@@H](c1ccc(OCc2ccc(-c3ccc(C(F)(F)F)cc3)s2)cc1)c1ccon1>>O=C(O)C[C@@H](c1ccc(OCc2ccc(-c3ccc(C(F)(F)F)cc3)s2)cc1)c1ccon1 -US20100286181A1,1,COC(=O)c1cnc(Br)s1.Cc1[nH]c(C(=O)NC2CCNCC23OCCO3)c(Cl)c1Cl>>COC(=O)c1cnc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)C3(C2)OCCO3)s1 -US20150133424A1,7,O=C(c1cccc([N+](=O)[O-])c1)N1CCOCC1>>Nc1cccc(C(=O)N2CCOCC2)c1 -US06645957B2,1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.CC(C)(C)OC(=O)N1CCC(CN)CC1>>CC(C)(C)OC(=O)N1CCC(CNCC2CCN(C(=O)OC(C)(C)C)CC2)CC1 -US20050113442A1,1,N#Cc1ccc(CBr)cc1.NC(=O)[C@@H]1CCCC[C@@H]1NS(=O)(=O)c1ccc(Cl)cc1>>N#Cc1ccc(CN([C@H]2CCCC[C@H]2C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20050148627A1,7,CCOC(=O)C1=Cc2cc(Cl)cc(C#Cc3ccccc3)c2OC1C(F)(F)F>>CCOC(=O)C1=Cc2cc(Cl)cc(CCc3ccccc3)c2OC1C(F)(F)F -US20060258740A1,3,CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1Br.OB(O)c1ccccc1F>>CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1-c1ccccc1F -US20030105280A1,6,CC(C)(C)OC(=O)NCCC(=O)N(CC(=O)NCc1ccc(C(=O)OCC#N)c(O)c1)CC(=O)NCc1ccc(C(=O)OCC#N)c(O)c1>>N#CCOC(=O)c1ccc(CNC(=O)CN(CC(=O)NCc2ccc(C(=O)OCC#N)c(O)c2)C(=O)CCN)cc1O -US08063234B2,1,C[S-].O=[N+]([O-])c1cccc(F)c1CBr>>CSCc1c(F)cccc1[N+](=O)[O-] -US20090069288A1,3,Brc1ccc(C2OCCO2)cc1.C#C[Si](C)(C)C>>C[Si](C)(C)C#Cc1ccc(C2OCCO2)cc1 -US20060264460A1,1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1c[nH]c2c(F)c(F)c(F)c(F)c12>>N#Cc1cnc2ccc(NCc3c[nH]c4c(F)c(F)c(F)c(F)c34)cc2c1Nc1ccc(F)c(Cl)c1 -US20050250784A1,2,COC(=O)c1cnc(N2CCN(S(=O)(=O)c3ccc(OC)c(OC)c3)CC2)s1.NO>>COc1ccc(S(=O)(=O)N2CCN(c3ncc(C(=O)NO)s3)CC2)cc1OC -US20060189601A1,6,CC(C)(C)OC(=O)N1CCCN(C(=O)CNC(=O)OCc2ccccc2)CC1>>O=C(NCC(=O)N1CCCNCC1)OCc1ccccc1 -US20070082853A1,6,CC(C)(C)OC(=O)NOC(C(=O)OCc1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NOC(C(=O)O)c1ccccc1 -US08394986B2,6,COC(=O)COc1ccc(Cl)cc1Oc1ccc(S(C)(=O)=O)c(C(F)(F)F)c1>>CS(=O)(=O)c1ccc(Oc2cc(Cl)ccc2OCC(=O)O)cc1C(F)(F)F -US05631270,1,Clc1ccncc1.Cn1ccc2cc(N)ccc21>>Cn1ccc2cc(Nc3ccncc3)ccc21 -US20090069323A1,6,COC(=O)c1cc(F)cc(CNS(=O)(=O)c2ccc(-c3ccc(F)cc3)cc2)c1>>O=C(O)c1cc(F)cc(CNS(=O)(=O)c2ccc(-c3ccc(F)cc3)cc2)c1 -US20050203081A1,3,CCOC(=O)COc1c(C(=O)OC)sc2c(Br)csc12.Nc1cccc(B(O)O)c1>>CCOC(=O)COc1c(C(=O)OC)sc2c(-c3cccc(N)c3)csc12 -US20050113442A1,1,N#Cc1ccc(CBr)cc1.NC(=O)[C@@H]1CCC[C@@H]1NS(=O)(=O)c1ccc(Cl)cc1>>N#Cc1ccc(CN([C@H]2CCC[C@H]2C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US05965539,6,COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1>>CC(C)C[C@H](NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1)C(=O)O -US06281363B1,7,CC(C)CC(C(=O)NN1C(=O)NC2(CCCCC2)C1=O)[C@H](CC=Cc1ccccc1)C(=O)NOC1CCCCO1>>CC(C)C[C@@H](C(=O)NN1C(=O)NC2(CCCCC2)C1=O)[C@H](CCCc1ccccc1)C(=O)NOC1CCCCO1 -US20030096856A1,7,COc1ccc([N+](=O)[O-])cc1NC(=O)OC(C)(C)C>>COc1ccc(N)cc1NC(=O)OC(C)(C)C -US20110009390A1,1,C[O-].Cc1cc(Cl)nc(Cl)c1>>COc1cc(C)cc(Cl)n1 -US20140088078A1,2,CCN1CCN(Cc2cc(F)ccc2S(=O)(=O)Cl)C(=O)C1.COC(=O)c1c(N)ccc2c1OCC1CC21>>CCN1CCN(Cc2cc(F)ccc2S(=O)(=O)Nc2ccc3c(c2C(=O)OC)OCC2CC32)C(=O)C1 -US05179112,2,COC(=O)c1ccc(Cc2c[nH]c3ccc(N)cc23)c(OC)c1.O=C(Cl)OC1CCCC1>>COC(=O)c1ccc(Cc2c[nH]c3ccc(NC(=O)OC4CCCC4)cc23)c(OC)c1 -US06821967B2,1,CC(C)(C)OC(=O)N1CCNCC1.Cn1c(Cl)nc2cccnc21>>Cn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2cccnc21 -US20110009389A1,2,COC(=O)CCS(=O)(=O)Cl.Clc1ccc2c(c1)CCNC2>>COC(=O)CCS(=O)(=O)N1CCc2cc(Cl)ccc2C1 -US04146631,2,Nc1nnn[nH]1.O=C(Cl)c1cc([N+](=O)[O-])ccc1O>>O=C(Nc1nnn[nH]1)c1cc([N+](=O)[O-])ccc1O -US20060058282A1,6,CC(C)(C)OC(=O)c1ccc(C2(C(=O)Oc3ccc(C(=O)NO)cc3)CCCCC2)cc1>>O=C(O)c1ccc(C2(C(=O)Oc3ccc(C(=O)NO)cc3)CCCCC2)cc1 -US20150252008A1,6,CCOC(=O)c1ccc(COc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)o1>>Nc1cnc(-c2ccc(C3CCC3)c(OCc3ccc(C(=O)O)o3)c2F)cn1 -US07659300B2,1,CC(C)(C)OC(=O)CBr.O=C1NCCN1c1ccccn1>>CC(C)(C)OC(=O)CN1CCN(c2ccccn2)C1=O -US08389513B2,2,C[C@]1(c2cc(N)ccc2Cl)N=C(N)OCC1(F)F.N#Cc1ccc(C(=O)O)nc1>>C[C@]1(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2Cl)N=C(N)OCC1(F)F -US20120232096A1,1,CCOc1ccc(Br)cc1.COc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)(C)C2>>CCOc1ccc(N2CCN(c3c(C)c4c(c(OC)c3C)OC(C)(C)C4)CC2)cc1 -US20120101136A1,1,CC(C)Oc1ccc(-c2nc(-c3ccc(O)cc3Cl)no2)cc1C#N.CCOC(=O)CBr>>CCOC(=O)COc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c(Cl)c1 -US08344135B2,2,CC(C)(C#N)c1cccc(C(=O)Nc2ccc(Cl)c(Oc3ccc4nc(N)sc4n3)c2)c1.O=C(Cl)CCl>>CC(C)(C#N)c1cccc(C(=O)Nc2ccc(Cl)c(Oc3ccc4nc(NC(=O)CCl)sc4n3)c2)c1 -US04156011,1,CC(C)(O)CCl.Oc1ccc(Oc2ccc(Cl)cc2)cc1>>CC(C)(O)COc1ccc(Oc2ccc(Cl)cc2)cc1 -US20110028509A1,2,CS(N)(=O)=O.O=C(O)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1>>CS(=O)(=O)NC(=O)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US08273745B2,2,NCCn1cc(C(c2ccccc2)c2ccccc2)ccc1=O.O=C(O)c1cccc2[nH]ccc12>>O=C(NCCn1cc(C(c2ccccc2)c2ccccc2)ccc1=O)c1cccc2[nH]ccc12 -US04474792,1,CI.Cc1cccc(C(=O)O)c1O>>COc1c(C)cccc1C(=O)O -US06498172B1,2,CCCCc1ccc(CNCc2cccc(CC(=O)OC)c2)cc1.Cn1cnc(S(=O)(=O)Cl)c1>>CCCCc1ccc(CN(Cc2cccc(CC(=O)OC)c2)S(=O)(=O)c2cn(C)cn2)cc1 -US08722702B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=Cc1ccc(NCc2ccc(Cl)cc2)nc1F>>CC(C)(C)OC(=O)N(Cc1ccc(Cl)cc1)c1ccc(C=O)c(F)n1 -US20130116243A1,1,BrCc1ccccn1.CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=O)CO4)cc2)CCC1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)N(Cc3ccccn3)C(=O)CO4)cc2)CCC1 -US06593322B1,2,Clc1ccc(NCCc2cccc(OCc3ccccc3)c2)cc1Cl.O=C(O)Cc1ccc(O)cc1>>O=C(Cc1ccc(O)cc1)N(CCc1cccc(OCc2ccccc2)c1)c1ccc(Cl)c(Cl)c1 -US07312241B2,8,COc1cc(OC)cc(C(O)c2ccc3c(c2)OCCO3)c1>>COc1cc(OC)cc(C(=O)c2ccc3c(c2)OCCO3)c1 -US03941803,1,O=C(c1ccccc1Cl)c1ccccc1-n1ccnc1CO.O=C1NC(=O)c2ccccc21>>O=C(c1ccccc1Cl)c1ccccc1-n1ccnc1CN1C(=O)c2ccccc2C1=O -US20050090534A1,8,O=C(CCc1oc(-n2cnc3ccccc32)nc1-c1ccc(Cl)cc1)N1CCSC1.O=C(OO)c1cccc(Cl)c1>>O=C(CCc1oc(-n2cnc3ccccc32)nc1-c1ccc(Cl)cc1)N1CCS(=O)C1 -US05475106,2,CC(O)c1cccc(N)c1.CCOC(=O)c1ccccc1N(CC(=O)N(C)c1ccccc1)C(=O)CN=C=O>>CCOC(=O)c1ccccc1N(CC(=O)N(C)c1ccccc1)C(=O)CNC(=O)Nc1cccc(C(C)O)c1 -US20150175623A1,1,CCCCn1nccc1COc1ccccc1C[C@@H](Oc1ncnc2sc(-c3ccc(F)nc3)c(-c3ccc(OCCN4CCN(C)CC4)c(Cl)c3C)c12)C(=O)OCC.COCCO>>CCCCn1nccc1COc1ccccc1C[C@@H](Oc1ncnc2sc(-c3ccc(OCCOC)nc3)c(-c3ccc(OCCN4CCN(C)CC4)c(Cl)c3C)c12)C(=O)OCC -US20060173204A1,7,CCOC(=O)C(=Cc1cccc(OCCc2ccc(OS(C)(=O)=O)cc2)c1)OCC>>CCOC(=O)C(Cc1cccc(OCCc2ccc(OS(C)(=O)=O)cc2)c1)OCC -US20040254227A1,7,O=[N+]([O-])c1cccc(C2=NOC(c3c(Cl)cccc3Cl)C2)c1>>Nc1cccc(C2=NOC(c3c(Cl)cccc3Cl)C2)c1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nccn4C)c(C)c2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nccn4C)c(C)c2)CCN3CC(C)C)cc1 -US20070129334A1,7,COc1cccc([N+](=O)[O-])c1Br>>COc1cccc(N)c1Br -US07612060B2,7,COC(=O)c1ccc([C@@H](C)n2cc(C[C@@H]3C(=O)NC=CN3S(=O)(=O)c3ccc(Cl)c(Cl)c3)nn2)cc1>>C[C@H](c1ccc(CO)cc1)n1cc(C[C@@H]2C(=O)NC=CN2S(=O)(=O)c2ccc(Cl)c(Cl)c2)nn1 -US20100121048A1,1,CC(C)N.Cc1cc(C(=O)N2CCN(Cc3ccccc3)CC2CC=O)c(-c2ccccc2)n1-c1ccccc1>>Cc1cc(C(=O)N2CCN(Cc3ccccc3)CC2CCNC(C)C)c(-c2ccccc2)n1-c1ccccc1 -US20110166161A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2nc(OCCOCc3ccccc3)c(C(N)=O)cc2F)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2nc(OCCO)c(C(N)=O)cc2F)CC1 -US20150239866A1,4,C#Cc1cc(C)cc(Nc2nccc(C(F)F)n2)c1.CC1=CC(N=[N+]=[N-])CCC1>>CC1=CC(n2cc(-c3cc(C)cc(Nc4nccc(C(F)F)n4)c3)nn2)CCC1 -US20090062282A1,7,CCOC(=O)CC(=O)/C=C/c1ccc2cc[nH]c2c1>>CCOC(=O)CC(=O)CCc1ccc2cc[nH]c2c1 -US20150152118A1,1,Clc1ccc(N2CCNCC2)cc1.N#CCCCBr>>N#CCCCN1CCN(c2ccc(Cl)cc2)CC1 -US07998972B2,1,Nc1ccccc1.O=[N+]([O-])c1cnc2ccc(Cl)cc2c1Cl>>O=[N+]([O-])c1cnc2ccc(Cl)cc2c1Nc1ccccc1 -US08247415B2,6,CC(C(=O)OCc1ccccc1)N1CCOC1=O>>CC(C(=O)O)N1CCOC1=O -US05278316,2,CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)O.NCCC1=CCCc2ccccc21>>CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCCC1=CCCc2ccccc21 -US06084133,9,ClP(c1ccccc1)c1ccccc1>>c1ccc(Pc2ccccc2)cc1 -US09085534B2,1,CN1CCC(CN)c2ccccc21.O=C(O)c1ccncc1F>>CN1CCC(CNc2cnccc2C(=O)O)c2ccccc21 -US07981460B2,2,CC(C)CCCCCCC(=O)O.CCOc1cc(CO)ccc1O>>CCOc1cc(COC(=O)CCCCCCC(C)C)ccc1O -US20090042841A1,1,Cc1ccc([N+](=O)[O-])c(Cl)n1.Cc1cccc(C#CC=C2CCNCC2)n1>>Cc1cccc(C#CC=C2CCN(c3nc(C)ccc3[N+](=O)[O-])CC2)n1 -US20080269214A1,6,COC(=O)c1ccc(-c2ccc(NC(=O)OC(C)(C)C)cc2)o1>>COC(=O)c1ccc(-c2ccc(N)cc2)o1 -US20130005719A1,7,CCOC(=O)/C=C/c1ccc(C(F)(F)C(O)(Cn2cnnn2)c2ccc(F)cc2F)nc1>>CCOC(=O)CCc1ccc(C(F)(F)C(O)(Cn2cnnn2)c2ccc(F)cc2F)nc1 -US07449581B2,1,CNc1ccc(F)cc1F.COC(=O)CBr>>COC(=O)CN(C)c1ccc(F)cc1F -US20140275172A1,6,COc1ccc(OC(F)(F)F)cc1C=O>>O=Cc1cc(OC(F)(F)F)ccc1O -US20130059849A1,2,CCn1ncc2c(C(=O)O)cc(C3CC3)nc21.Cc1cc(C)c(CN)c(=O)[nH]1>>CCn1ncc2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(C3CC3)nc21 -US20090306123A1,1,Cc1c(C=O)ccnc1Cl.NC1CC1>>Cc1c(CNC2CC2)ccnc1Cl -US07834043B2,2,COC(=O)Cl.NC(=O)NCC(N)C(=O)O>>COC(=O)N[C@@H](CNC(N)=O)C(=O)O -US05011992,1,CCN(CC)C(=O)CCCCl.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1O>>CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCCC(=O)N(CC)CC -US20110034654A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)[C@@H]1C[C@@H](O)CN1>>CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O -US05726205,2,CN(C)Cc1ccc([C@@H]2CC[C@@H](O)CC2)cc1.O=C(Cl)c1ccc(Cl)cc1>>CN(C)Cc1ccc([C@@H]2CC[C@@H](OC(=O)c3ccc(Cl)cc3)CC2)cc1 -US04662933,2,CC(C)(C)NS(=O)(=O)c1ccccc1CCO.CS(=O)(=O)Cl>>CC(C)(C)NS(=O)(=O)c1ccccc1CCOS(C)(=O)=O -US04168964,1,CCOC(=O)NN.Cc1nc(C=O)c[nH]1>>CCOC(=O)NN=Cc1c[nH]c(C)n1 -US08859768B2,3,Cc1cnc(NC(=O)C2CC2)cc1[Sn](C)(C)C.NC(=O)c1nc(I)oc1-c1ccccc1Cl>>Cc1cnc(NC(=O)C2CC2)cc1-c1nc(C(N)=O)c(-c2ccccc2Cl)o1 -US20050222139A1,2,CN(Cc1cccc(C(=O)O)c1)C(=O)OC(C)(C)C.O=C1CNc2ccccc2N1>>CN(Cc1cccc(C(=O)N2CC(=O)Nc3ccccc32)c1)C(=O)OC(C)(C)C -US04312876,1,CCOC(=O)N1CC[C@@H](O)[C@H](c2ccccc2)C1.Oc1ccccc1F>>CCOC(=O)N1CC[C@H](Oc2ccccc2F)[C@H](c2ccccc2)C1 -US20090318690A1,1,CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCNCC3)noc12.Cn1c(C#N)ccc1C=O>>CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCN(Cc4ccc(C#N)n4C)CC3)noc12 -US06143777,7,CCc1cc(C(=O)NCc2cccc([N+](=O)[O-])c2)c(NC(=O)C2CCC(C(=O)O)CC2)s1>>CCc1cc(C(=O)NCc2cccc(N)c2)c(NC(=O)C2CCC(C(=O)O)CC2)s1 -US20090186900A1,3,CC(=O)c1ccc(Br)cc1.OB(O)c1ccc(O)cc1>>CC(=O)c1ccc(-c2ccc(O)cc2)cc1 -US04092150,1,CC(C)N.CCNc1nc(Cl)c(C#N)c(Cl)n1>>CCNc1nc(Cl)c(C#N)c(NC(C)C)n1 -US05726194,7,O=[N+]([O-])c1cccc(S(=O)(=O)Nc2ccc3nsnc3c2)c1>>Nc1cccc(S(=O)(=O)Nc2ccc3nsnc3c2)c1 -US20110021500A1,2,CCNCc1ccccc1.O=C(O)c1cc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)ncn1>>CCN(Cc1ccccc1)C(=O)c1cc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)ncn1 -US05444071,4,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].CCc1cc(OCc2ccc(-c3ccccc3C#N)cc2)c2ccccc2n1>>CCc1cc(OCc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)c2ccccc2n1 -US20120088913A1,1,COc1cnc(Cl)n2nc(N)nc12.C[O-]>>COc1cnc(OC)n2nc(N)nc12 -US20150038490A1,6,O=C(OCc1ccccc1)N1CC[C@@H](c2ccccc2)C[C@H]1C1CCCC(F)(F)C1>>FC1(F)CCCC([C@@H]2C[C@H](c3ccccc3)CCN2)C1 -US04711898,2,CCO.O=C(O)c1ccc2c(c1)C(=O)CC(c1ccccc1)=N2>>CCOC(=O)c1ccc2c(c1)C(=O)CC(c1ccccc1)=N2 -US20070032485A1,1,CC[C@@H]1C[C@H](Nc2ncc(O)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OCC(C)(C)C(=O)OC.N#CCCCBr>>CC[C@@H]1C[C@H](Nc2ncc(OCCCC#N)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OCC(C)(C)C(=O)OC -US20040220403A1,2,CC(C)(C)OC(=O)N1C[C@@H](C(c2ccccc2)c2ccccc2)N2CCNC[C@H]2C1.CN(C)C(=O)Cl>>CN(C)C(=O)N1CCN2[C@@H](CN(C(=O)OC(C)(C)C)C[C@H]2C(c2ccccc2)c2ccccc2)C1 -US07749998B2,1,CN.O=C(CN1CCCC1)c1ccc(Br)cc1>>CNC(CN1CCCC1)c1ccc(Br)cc1 -US20060142337A1,6,C[C@@H](O[C@H]1CCN(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CCN(C(=O)NC2CCNCC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090118284A1,1,CI.COC(=O)C1(NC=O)CCN(C(=O)OC(C)(C)C)C1>>COC(=O)C1(N(C)C=O)CCN(C(=O)OC(C)(C)C)C1 -US08263768B2,1,COc1cc2ncnc(Cl)c2cc1O[C@@H]1CC[C@@H](N2CCN(C)C(=O)C2)CC1.Nc1cccc(Cl)c1F>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O[C@@H]1CC[C@@H](N2CCN(C)C(=O)C2)CC1 -US20070010537A1,1,CI.O=C1CN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)c2ccccc2N1>>CN1C(=O)CN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)c2ccccc21 -US20130178461A1,7,CN(C)CCOc1cnc([N+](=O)[O-])cn1>>CN(C)CCOc1cnc(N)cn1 -US08404866B2,1,CC(C)(C)OC(=O)N1C[C@@H](SC(C)(C)C)[C@H](NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1.CI>>CN([C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1SC(C)(C)C)S(=O)(=O)c1ccc(Oc2ccccc2)cc1 -US20100093705A1,3,C=CC(=O)N(C)Cc1oc2ccccc2c1CC.CC1(C)NCc2cc(Br)cnc2NC1=O>>CCc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CNC(C)(C)C(=O)N3)oc2ccccc12 -US08450319B2,3,CCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.C[Si](C)(C)CCOCn1ncc2c(c(C=O)c(-c3ccc(OC(F)F)c(OC4CC4)c3)n2COCC[Si](C)(C)C)c1=O>>CCCC=Cc1c(-c2ccc(OC(F)F)c(OC3CC3)c2)n(COCC[Si](C)(C)C)c2cnn(COCC[Si](C)(C)C)c(=O)c12 -US20010051631A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=S(=O)(NCCCNCc1cccc2nccn12)C(F)(F)F>>CC(C)(C)OC(=O)N(CCCNS(=O)(=O)C(F)(F)F)Cc1cccc2nccn12 -US05585394,2,COc1ccc(S(=O)(=O)Cl)c(OC)c1.O=c1[nH]c2ccc(Cl)cc2n1-c1cccc(Cl)c1>>COc1ccc(S(=O)(=O)n2c(=O)n(-c3cccc(Cl)c3)c3cc(Cl)ccc32)c(OC)c1 -US20100068301A1,6,CCOC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OC[C@@H]3CCCN3C(=O)C(C)C)ccc2n1Cc1ccc(Cl)cc1>>CC(C)C(=O)N1CCC[C@H]1COc1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n2Cc1ccc(Cl)cc1 -US20150252030A1,3,Cc1cc(C)c(O)c(Br)c1.OB(O)c1ccco1>>Cc1cc(C)c(O)c(-c2ccco2)c1 -US07910556B2,2,CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)C(=O)O.CCOC(=O)CNC(=O)CN>>CCOC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C -US08735584B2,3,C#Cc1ccccc1.O=c1[nH]c2nccc(Cl)c2c2ccccc12>>O=c1[nH]c2nccc(C#Cc3ccccc3)c2c2ccccc12 -US06703392B2,1,CCCCBr.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NC1CCc3ccccc31)CC2>>CCCCOc1cc2c(cc1OC)CCN(CC(=O)NC1CCc3ccccc31)C2Cc1ccc(OC)c(OC)c1 -US20110190227A1,2,CC(C)(C)C(=O)Cl.CCOC(=O)Cc1ccc(OC)c(Oc2ccc(N)cc2CSC(C)C)c1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(NC(=O)C(C)(C)C)cc2CSC(C)C)c1 -US05958954,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(C(C)C)cc2)=CC(C)(C)O3)cc1>>CC(C)c1ccc(C2=CC(C)(C)Oc3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 -US06664258B1,1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCN(c2ccc(C#N)c(F)c2)CC1 -US20140187769A1,2,CC[C@@H](c1ccccc1)N1Cc2cc3c(cc2C[C@H]1C(=O)O)N(C)C(=O)[C@H](c1ccc(O)cc1)O3.COC(=O)[C@@H](N)Cc1ccc(-c2ccc(Cl)cc2)cc1>>CC[C@@H](c1ccccc1)N1Cc2cc3c(cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(-c2ccc(Cl)cc2)cc1)C(=O)OC)N(C)C(=O)[C@H](c1ccc(O)cc1)O3 -US20090215759A1,7,COc1cc([N+](=O)[O-])ccc1-c1sc(C)nc1C>>COc1cc(N)ccc1-c1sc(C)nc1C -US04894386,3,CN(C)C=O.O=Cc1ccc2cc[nH]c2c1>>O=Cc1ccc2c(C=O)c[nH]c2c1 -US20120190680A1,1,COC(=O)c1c[nH]c2ccccc12.Clc1ncccn1>>COC(=O)c1cn(-c2ncccn2)c2ccccc12 -US20020188120A1,6,CCCCOc1ccc(S(=O)(=O)C2(C(=O)OCC)CCN(Cc3ccncc3)CC2)cc1>>CCCCOc1ccc(S(=O)(=O)C2(C(=O)O)CCN(Cc3ccncc3)CC2)cc1 -US05451592,3,Cc1ccc(B(O)O)cc1.N#Cc1cccnc1Br>>Cc1ccc(-c2ncccc2C#N)cc1 -US20040058932A1,7,C[C@H]1CN(C(=O)COc2ccc(Cl)cc2[N+](=O)[O-])[C@H](C)CN1Cc1ccc(F)cc1>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2N)[C@H](C)CN1Cc1ccc(F)cc1 -US20140107078A1,1,CCOC(=O)CBr.O=Cc1ccc(O)c(C(F)(F)F)c1>>CCOC(=O)COc1ccc(C=O)cc1C(F)(F)F -US04820723,1,BrCCCCBr.CCCc1c(O)ccc(C(C)=O)c1O>>CCCc1c(OCCCCBr)ccc(C(C)=O)c1O -US20130310411A1,1,Clc1c2ccccc2nc2cccc(Br)c12.Oc1ccc(S)cc1>>Oc1ccc(Sc2c3ccccc3nc3cccc(Br)c23)cc1 -US20080015237A1,9,NO.O=Cc1ccc2c(c1)OC(F)(F)O2>>ON=Cc1ccc2c(c1)OC(F)(F)O2 -US08686167B2,2,CC/C=C\C/C=C\CCO.Cc1ccc(S(=O)(=O)Cl)cc1>>CC/C=C\C/C=C\CCOS(=O)(=O)c1ccc(C)cc1 -US20100112545A1,3,CC(C)[Si](Oc1ccc(C=O)cc1)(C(C)C)C(C)C.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1 -US20100216986A1,6,CC(C)[Si](Oc1ccc(-c2ccc(CO)[se]2)cc1)(C(C)C)C(C)C>>OCc1ccc(-c2ccc(O)cc2)[se]1 -US20100113504A1,2,C=CCOC(CCCCCC(=O)OC)C(=O)O.C=Cc1cc(COc2ccccc2N)cc(OC)c1>>C=CCOC(CCCCCC(=O)OC)C(=O)Nc1ccccc1OCc1cc(C=C)cc(OC)c1 -US20150133368A1,2,C#CCC(NC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(=O)O.COC(=O)C([NH3+])CCC(=O)NCCCN=[N+]=[N-]>>C#CCC(NC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)NCCCN=[N+]=[N-])C(=O)OC -US07199239B2,6,CCCCN(Cc1ccc(OCC(=O)OCC)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)c1C>>CCCCN(Cc1ccc(OCC(=O)O)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)c1C -US08188093B2,2,Cc1nc(OCC2CC2)c(Br)cc1C(=O)O.N[C@@H]1CCCC[C@H]1O>>Cc1nc(OCC2CC2)c(Br)cc1C(=O)N[C@@H]1CCCC[C@H]1O -US20060258866A1,2,CCCCCCCCNCc1ccc(F)cc1F.CCOC(=O)[C@H](Cc1ccc(OCC(=O)O)cc1)OCC>>CCCCCCCCN(Cc1ccc(F)cc1F)C(=O)COc1ccc(C[C@H](OCC)C(=O)OCC)cc1 -US20090105252A1,2,CN1CCNCC1.COc1cc(Cl)ccc1C(=O)O>>COc1cc(Cl)ccc1C(=O)N1CCN(C)CC1 -US20140142084A1,1,CO.COc1cc(C2CCNCC2)ccc1Nc1ncc(OCc2c(Cl)c(OC)cc(OC)c2Cl)cn1>>COc1cc(C2CCN(C)CC2)ccc1Nc1ncc(OCc2c(Cl)c(OC)cc(OC)c2Cl)cn1 -US20110237620A1,7,CC(C)(C)OC(=O)NCc1cccc([N+](=O)[O-])c1>>CC(C)(C)OC(=O)NCc1cccc(N)c1 -US20030195199A1,2,CCCCCCCCN.CCCCCCCCNC(=O)Nc1sc(C(=O)O)c(C)c1C(=O)OC(C)(C)C>>CCCCCCCCNC(=O)Nc1sc(C(=O)NCCCCCCCC)c(C)c1C(=O)OC(C)(C)C -US20110136821A1,2,O=C(O)Cc1ccccc1C(F)(F)F.O=C1Nc2ccccc2C12CCNCC2>>O=C(Cc1ccccc1C(F)(F)F)N1CCC2(CC1)C(=O)Nc1ccccc12 -US20130317024A1,6,CCOC(=O)Cc1ccc(OC)c(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c1>>COc1ccc(CC(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O -US20080188527A1,7,O=Cc1ccc(-c2cccnc2)o1>>OCc1ccc(-c2cccnc2)o1 -US20100063108A1,6,CCc1cc(-c2nnc(-c3cc(C)nc(C(C)C)c3)s2)cc(C)c1OCc1ccccc1>>CCc1cc(-c2nnc(-c3cc(C)nc(C(C)C)c3)s2)cc(C)c1O -US20150087626A1,6,COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CCC3CC3N2C(=O)OC(C)(C)C)cc1>>COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CCC3CC3N2)cc1 -US07317009B2,1,CC(C)c1nn2c(Cl)ccc2c(-c2ccc(F)cc2)c1C=O.NCCO>>CC(C)c1nn2c(Cl)ccc2c(-c2ccc(F)cc2)c1CNCCO -US20110190351A1,2,COc1ccc(N)c2nc(-c3cccs3)[nH]c12.O=C(O)/C=C/c1cnc[nH]1>>COc1ccc(NC(=O)/C=C/c2cnc[nH]2)c2nc(-c3cccs3)[nH]c12 -US07790720B2,7,CC1CCCN1CCCOc1ccc(-c2nc(CN3C(=O)CC[C@H]3CN3CCOCC3)co2)cc1>>CC1CCCN1CCCOc1ccc(-c2nc(CN3CCC[C@H]3CN3CCOCC3)co2)cc1 -US20150018547A1,1,COC(=O)CC(=O)CCl.COc1cc(S)cc(C(F)(F)F)c1>>COC(=O)CC(=O)CSc1cc(OC)cc(C(F)(F)F)c1 -US20060046987A1,1,COC(=O)Cc1cnc(N)s1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)Cc1cnc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)s1 -US20100004269A1,1,COC(=O)c1ccc2cncn2c1Cl.Nc1ccc(I)cc1F>>COC(=O)c1ccc2cncn2c1Nc1ccc(I)cc1F -US09156823B2,3,CC(C)(C)OC(=O)N1CCCC1c1ncc(-c2ccc3cc(Br)ccc3c2)[nH]1.COC(=O)NC(C(=O)N1C2CCC(C2)C1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C>>COC(=O)NC(C(=O)N1C2CCC(C2)C1c1ncc(-c2ccc(-c3ccc4cc(-c5cnc(C6CCCN6C(=O)OC(C)(C)C)[nH]5)ccc4c3)cc2)[nH]1)C(C)C -US20150225405A1,2,C1COCCN1.O=C(O)c1ccc(Cn2c3ccc(F)cc3c3c2cnn3C2CCCCO2)cc1>>O=C(c1ccc(Cn2c3ccc(F)cc3c3c2cnn3C2CCCCO2)cc1)N1CCOCC1 -US04680402,1,CC1CCNCC1.Cc1ccc(C(=O)c2cc([N+](=O)[O-])ccc2Cl)cc1>>Cc1ccc(C(=O)c2cc([N+](=O)[O-])ccc2N2CCC(C)CC2)cc1 -US04602027,7,CCc1oc(C=Cc2ccccc2)nc1C(=O)O>>CCc1oc(C=Cc2ccccc2)nc1CO -US20050043336A1,1,CN1CCC(Oc2cccc3ncnc(Nc4ccc(O)c(F)c4)c23)CC1.Fc1cccc(CCl)c1>>CN1CCC(Oc2cccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(F)c4)c23)CC1 -US08138174B2,7,O=C(CCCN1CCNCC1)c1c[nH]c2ccc(F)cc12>>Fc1ccc2[nH]cc(CCCCN3CCNCC3)c2c1 -US20130267516A1,1,CCOc1cccc([C@@H](C)N)c1.O=C1CC[C@@H](c2ccc(F)nc2)C1>>CCOc1cccc([C@@H](C)N[C@H]2CC[C@@H](c3ccc(F)nc3)C2)c1 -US04638002,1,O=C(C[PH4])CCl.Oc1cccc(Cl)c1>>O=C(C[PH4])COc1cccc(Cl)c1 -US20090099178A1,1,C[C@H]1CCC[C@@H](C)N1C(=O)CCl.Oc1ccc2cc(Br)ccc2c1>>C[C@H]1CCC[C@@H](C)N1C(=O)COc1ccc2cc(Br)ccc2c1 -US07446222B2,1,CCOC(=O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2O)c1.OCCc1ccccc1>>CCOC(=O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCCc2ccccc2)c1 -US20060247320A1,9,CCOC(=O)c1cc2cc3c(nc2s1)CCC([Si](C)(C)C)C3.N>>C[Si](C)(C)C1CCc2nc3sc(C(N)=O)cc3cc2C1 -US04053601,6,CNC(=O)CCC(=O)c1c(OC)cccc1OC>>CNC(=O)CCC(=O)c1c(O)cccc1OC -US08318949B2,6,CCOC(=O)c1sc(N2C(=O)N(Cc3ccc(F)cc3)C[C@@H]2C)nc1C>>Cc1nc(N2C(=O)N(Cc3ccc(F)cc3)C[C@@H]2C)sc1C(=O)O -US20150011548A1,6,CC(=O)Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1>>Nc1cc(-n2cccc2)cc(-n2cnc3cc(-c4cnco4)ccc32)c1 -US20090105219A1,9,CC12CNc3ccc(Br)c(c31)NC(=O)C2.N#C[Cu]>>CC12CNc3ccc(C#N)c(c31)NC(=O)C2 -US20090137609A1,6,CCOC(=O)Cc1cnc(-c2ccc(C(CC)(CC)c3ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c3)cc2C)nc1>>CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ncc(CC(=O)O)cn2)c(C)c1 -US20110086834A1,1,Nc1cc(I)ccc1OC1CCOCC1.Nc1ncc(Cl)c(Cl)n1>>Nc1ncc(Cl)c(Nc2cc(I)ccc2OC2CCOCC2)n1 -US20130237525A1,7,COC(=O)c1ccnc(OC(F)F)c1>>OCc1ccnc(OC(F)F)c1 -US08304557B2,2,Cc1nc(C(=O)Cl)c(C)o1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>Cc1nc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)c(C)o1 -US20130225548A1,1,Cc1cc(Br)ncc1Br.O=S1(=O)CCNCC1>>Cc1cc(N2CCS(=O)(=O)CC2)ncc1Br -US07196090B2,6,CNc1ncc2c(n1)N(C1CCN(C(=O)OC(C)(C)C)CC1)C(=O)N(c1c(F)c(OC)cc(OC)c1F)C2>>CNc1ncc2c(n1)N(C1CCNCC1)C(=O)N(c1c(F)c(OC)cc(OC)c1F)C2 -US20140024650A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](OCC1OCCCC1N)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NC1CCCOC1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C -US20040132733A1,7,COC(=O)C[C@H]1Nc2ccccc2NC1=O>>O=C1Nc2ccccc2N[C@@H]1CCO -US20020052498A1,2,CCCCCCCCCCCCCCCCCCN=C=O.CN(C)CCCNC(=O)CCc1ccccc1O>>CCCCCCCCCCCCCCCCCCNC(=O)Oc1ccccc1CCC(=O)NCCCN(C)C -US20030095958A1,6,COC(=O)C1CN(C(=O)OC(C)(C)C)CCc2c1[nH]c1ccccc21>>CC(C)(C)OC(=O)N1CCc2c([nH]c3ccccc23)C(C(=O)O)C1 -US04753674,2,CCC(Oc1ccc(Cl)c(C(F)(F)F)c1)C(=O)Cl.NCc1ccncc1>>CCC(Oc1ccc(Cl)c(C(F)(F)F)c1)C(=O)NCc1ccncc1 -US04753953,1,C[C@H]1CNC[C@H]1NC(=O)OC(C)(C)C.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>C[C@H]1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C[C@H]1NC(=O)OC(C)(C)C -US20090156582A1,6,Cc1ccc(C(=O)Nc2cn(C3CCCCO3)nc2C(=O)NCC(F)(F)F)cn1>>Cc1ccc(C(=O)Nc2c[nH]nc2C(=O)NCC(F)(F)F)cn1 -US20060128790A1,1,CCOC(=O)C1(COS(C)(=O)=O)CC1.Cc1c(O)ccc(OCc2ccccc2)c1C>>CCOC(=O)C1(COc2ccc(OCc3ccccc3)c(C)c2C)CC1 -US07968563B2,1,CON.Cc1nc(N)c2nc(CCl)n(CC(C)C)c2c1C>>CONCc1nc2c(N)nc(C)c(C)c2n1CC(C)C -US20120015907A1,1,BrCCCCBr.CCc1cc2c(C(=O)NC)c(-c3ccc(F)cc3)oc2nc1NS(C)(=O)=O>>CCc1cc2c(C(=O)NC)c(-c3ccc(F)cc3)oc2nc1N(CCCCBr)S(C)(=O)=O -US06235900B1,2,Cn1ccc(-c2ccc(C(=O)O)c(Cl)c2)n1.c1cnc2c(c1)CNc1ccccc1N2>>Cn1ccc(-c2ccc(C(=O)N3Cc4cccnc4Nc4ccccc43)c(Cl)c2)n1 -US05665856,1,COc1ccc(-c2ccc(O)cc2)cc1.OCCCCCCBr>>COc1ccc(-c2ccc(OCCCCCCO)cc2)cc1 -US20090270363A1,6,COc1cc(N(C)C)ccc1-c1nc2c(s1)C(O)CCC2>>CN(C)c1ccc(-c2nc3c(s2)C(O)CCC3)c(O)c1 -US20080234296A1,7,O=Cc1cc(I)ccc1F>>OCc1cc(I)ccc1F -US20140057937A1,2,COC(=O)C1CCc2c(cnn2-c2ccc(F)cc2)N1.Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O>>COC(=O)C1CCc2c(cnn2-c2ccc(F)cc2)N1C(=O)Cn1nc(C(F)(F)F)c(Cl)c1C -US04577011,7,CC1Cc2cccc([N+](=O)[O-])c2O1>>CC1Cc2cccc(N)c2O1 -US05134128,3,Brc1ccc(I)cc1.C#CCCC>>CCCC#Cc1ccc(Br)cc1 -US06864255B2,1,Clc1ncnc(-n2c(Cl)nc3ccccc32)n1.Nc1cccc(Cc2nnn[nH]2)c1>>Clc1nc2ccccc2n1-c1ncnc(Nc2cccc(Cc3nnn[nH]3)c2)n1 -US20150266822A1,6,COC(=O)c1cc(OCC2COC(C)(C)O2)cc(-c2ccc(C)cc2C#N)c1>>Cc1ccc(-c2cc(OCC3COC(C)(C)O3)cc(C(=O)O)c2)c(C#N)c1 -US07589232B2,2,CCCCc1ccc(C#Cc2ccc(CNc3ccc4c(c3)C(=O)OC(C)(C)O4)cn2)cc1.O=C(Cl)CCC1CCCC1>>CCCCc1ccc(C#Cc2ccc(CN(C(=O)CCC3CCCC3)c3ccc4c(c3)C(=O)OC(C)(C)O4)cn2)cc1 -US04927819,2,COc1ccc2c(c1)C=Cc1ccccc1C2CO.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc2c(c1)C=Cc1ccccc1C2COS(=O)(=O)c1ccc(C)cc1 -US20030216410A1,3,Cc1[nH]c(C=O)c(C)c1C(=O)NCCN1CCCC1.O=C1Cc2cc(-c3ccccc3)ccc2N1>>Cc1[nH]c(C=C2C(=O)Nc3ccc(-c4ccccc4)cc32)c(C)c1C(=O)NCCN1CCCC1 -US20080021059A1,2,CC(=O)OC(C)=O.CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)NN)n2n1>>CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)NNC(C)=O)n2n1 -US06162809,1,Cc1c(SCCCCl)ccnc1CCl.Sc1ccncc1>>Cc1c(SCCCCl)ccnc1CSc1ccncc1 -US04536505,3,O=C(O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cn(-c2cccnc2)c2ccccc12>>O=C(O)CCCCC=Cc1cn(-c2cccnc2)c2ccccc12 -US05801170,2,CC(C)c1ccc(N)cc1OCCN(C)C.Cc1nc(-c2ccc(-c3ccc(C(=O)O)cc3)c(C)c2)no1>>Cc1nc(-c2ccc(-c3ccc(C(=O)Nc4ccc(C(C)C)c(OCCN(C)C)c4)cc3)c(C)c2)no1 -US20090018150A1,6,CCOc1ccc2ccccc2c1-c1c[nH]c(NC(C)=O)n1>>CCOc1ccc2ccccc2c1-c1c[nH]c(N)n1 -US20040267012A1,1,C1COCCN1.Nc1nnc(Cl)s1>>Nc1nnc(N2CCOCC2)s1 -US04845231,4,N#CCc1ccc(OCC2CCCCC2)cc1.[N-]=[N+]=[N-]>>c1cc(OCC2CCCCC2)ccc1Cc1nnn[nH]1 -US07544835B2,9,CCOc1ccc([C@@H](O)[C@H](OC(C)C)C(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)cc1>>CCOc1ccc(C[C@H](OC(C)C)C(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)cc1 -US05998452,2,C=CC(=O)Cl.CC(C)(C)c1cc(C2NCCS2)cc(C(C)(C)C)c1O>>C=CC(=O)N1CCSC1c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 -US20150191502A1,6,COc1ccc(Cc2cc(Br)ccc2Cl)cc1>>Oc1ccc(Cc2cc(Br)ccc2Cl)cc1 -US20120053173A1,6,CCOC(=O)CCNC(=O)c1ccc(NC(CCCCOC)c2oc3ccc(OC)cc3c2C)cc1>>COCCCC[C@H](Nc1ccc(C(=O)NCCC(=O)O)cc1)c1oc2ccc(OC)cc2c1C -US08354444B2,6,CCOC(=O)c1ccc(CNC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)nc1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCc2ccc(C(=O)O)cn2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20150087672A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(I)cn1>>Cc1ccc(S(=O)(=O)Nc2ccc(I)cn2)cc1 -US20120295897A1,9,O=C1N(C(c2ccccc2)c2ccccc2)c2ccc(F)cc2C1(O)c1cc2c(cc1O)OCC2>>O=C1C(c2cc3c(cc2O)OCC3)c2cc(F)ccc2N1C(c1ccccc1)c1ccccc1 -US05112988,6,CN(C(=O)OC(C)(C)C)c1ccccc1CC(=O)N1CC2C(=O)CCC(c3ccccc3)(c3ccccc3)C2C1>>CNc1ccccc1CC(=O)N1CC2C(=O)CCC(c3ccccc3)(c3ccccc3)C2C1 -US05998409,2,NCC1CCN(Cc2ccccc2)CC1.O=C(O)c1c[nH]c2ccccc12>>O=C(NCC1CCN(Cc2ccccc2)CC1)c1c[nH]c2ccccc12 -US06465060B1,1,CCCC1CCC(CO)S1.CCCCCCCCCCCc1cnc(-c2ccc(O)cc2)nc1>>CCCCCCCCCCCc1cnc(-c2ccc(OCC3CCC(CCC)S3)cc2)nc1 -US07132456B2,2,CN(C)CCN.O=C(O)c1cccc(-c2ccccc2CSCCOc2ccccc2)c1>>CN(C)CCNC(=O)c1cccc(-c2ccccc2CSCCOc2ccccc2)c1 -US07517873B2,1,CN1C(=O)C2(CC2)CN(C2CCCC2)c2nc(Cl)ncc21.Cc1cc(C(=O)O)ccc1N>>Cc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC1(CC1)C(=O)N2C -US20150105373A1,3,CC(C)(O)C(NC(=O)N1CC(=O)N(COCC[Si](C)(C)C)c2cc(I)cnc21)c1ccc(OC(F)(F)F)c(F)c1.OB(O)C1CC1>>CC(C)(O)C(NC(=O)N1CC(=O)N(COCC[Si](C)(C)C)c2cc(C3CC3)cnc21)c1ccc(OC(F)(F)F)c(F)c1 -US20120059014A1,1,CC(C)(C)OC(=O)N[C@H]1CNC[C@@H]1N1CCCCC1=O.CC(C)OC(=O)N1CCC([C@H](C)CCOc2cnc(Cl)nc2)CC1>>CC(C)OC(=O)N1CCC([C@H](C)CCOc2cnc(N3C[C@H](NC(=O)OC(C)(C)C)[C@@H](N4CCCCC4=O)C3)nc2)CC1 -US04006150,8,CS(=O)(=O)Cc1ccccn1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)Cc1cccc[n+]1[O-] -US20100160308A1,7,CS(=O)(=O)Oc1ccc(F)cc1C=O>>CS(=O)(=O)Oc1ccc(F)cc1CO -US20150141409A1,2,O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1.OCC1CCCCC1>>O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)OCC1CCCCC1)c1ccc(Cl)cc1 -US09096524B2,2,CSc1ccc(NC2CCNCC2)cc1C(F)(F)F.O=C(O)CCCN1CCN(c2ccc(C(F)(F)F)cc2)CC1>>CSc1ccc(NC2CCN(C(=O)CCCN3CCN(c4ccc(C(F)(F)F)cc4)CC3)CC2)cc1C(F)(F)F -US20050176702A1,2,Brc1ccc2c(c1)CCN2.O=C(Cl)C=Cc1cccc(Cl)c1>>O=C(/C=C/c1cccc(Cl)c1)N1CCc2cc(Br)ccc21 -US05025014,4,CSc1ccc(N)c(C(=O)O)c1.O=CNCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)CC1>>CSc1ccc2ncn(CCN3CCC(Nc4nc5ccccc5n4Cc4ccc(F)cc4)CC3)c(=O)c2c1 -US20070281937A1,2,COc1ccccc1-c1nc(C(=O)O)cn1-c1ccc(C)cc1.Nc1ccc(F)cc1>>COc1ccccc1-c1nc(C(=O)Nc2ccc(F)cc2)cn1-c1ccc(C)cc1 -US09049878B2,2,CCOC(=O)c1c(C)nc2cccc(OC[C@@H](N)C(C)C)c2c1N.O=C(O)c1cccc(O)c1>>CCOC(=O)c1c(C)nc2cccc(OC[C@@H](NC(=O)c3cccc(O)c3)C(C)C)c2c1N -US07915281B2,7,C#CCNc1c([N+](=O)[O-])c(Cl)nc2ccccc12>>C#CCNc1c(N)c(Cl)nc2ccccc12 -US07569578B2,1,BrCc1ccccc1.Cc1cc(CC(NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2ncc[nH]2)cc2cn[nH]c12>>Cc1cc(CC(NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2nccn2Cc2ccccc2)cc2cn[nH]c12 -US20090318690A1,6,CN(C)Cc1c(OCc2ccc(C#N)cc2)ccc2c(CCC3CCN(C(=O)OC(C)(C)C)CC3)noc12>>CN(C)Cc1c(OCc2ccc(C#N)cc2)ccc2c(CCC3CCNCC3)noc12 -US07199244B2,6,CC(C)(C)NCc1ccc2c(c1)CCCC2NC(=O)CC1CC(OCc2ccccc2)CN1S(=O)(=O)c1cccc(C(F)(F)F)c1>>CC(C)(C)NCc1ccc2c(c1)CCCC2NC(=O)CC1CC(O)CN1S(=O)(=O)c1cccc(C(F)(F)F)c1 -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.N#Cc1ccc(C=O)c2ccccc12>>COc1cc(O)c2c(c1C(=O)NCc1ccc(C#N)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US20120058984A1,3,CC1(C)OB(c2cncc(C#N)c2)OC1(C)C.O[C@@H]1CC[C@@H](Nc2nc(CN3CCCCC3)cc(Nc3nc4ccc(Br)cc4s3)n2)CC1>>N#Cc1cncc(-c2ccc3nc(Nc4cc(CN5CCCCC5)nc(N[C@@H]5CC[C@@H](O)CC5)n4)sc3c2)c1 -US06037363,6,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O -US20150099737A1,1,CC(C)(C)OC(=O)N1C2CCC1CN(C(=O)c1ccc(N)nc1)C2.CN(C)C(=O)c1cc2cnc(Cl)nc2n1C(C)(C)C>>CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCC(C4)N5C(=O)OC(C)(C)C)cn3)nc2n1C(C)(C)C -US04626276,8,CCCC(=NOCC=CCl)[C@@H]1C(=O)C[C@@H](CC(C)SCC)CC1=O.OO>>CCCC(=NOCC=CCl)[C@@H]1C(=O)C[C@@H](CC(C)S(=O)CC)CC1=O -US05728706,3,C#C[Si](C)(C)C.Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(Br)cn2)cc1>>Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(C#C[Si](C)(C)C)cn2)cc1 -US20050107389A1,9,[N-]=[N+]=NC[C@@H]1C[C@H]1CN1CCN(c2csc3cc(C(F)(F)F)ccc23)CC1>>NC[C@@H]1C[C@H]1CN1CCN(c2csc3cc(C(F)(F)F)ccc23)CC1 -US20070032542A1,6,COC(=O)[C@H]1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1>>O=C(O)[C@H]1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1 -US07087597B1,1,CCOC(=O)c1cnc(N2CCc3ccccc32)nc1O.COc1ccc(CCl)cc1>>CCOC(=O)c1cnc(N2CCc3ccccc32)nc1OCc1ccc(OC)cc1 -US20150164861A1,1,CCOC(=O)c1cccc(Sc2c(C)[nH]c3cc(Cl)ccc23)c1.FC(F)(F)Cn1cc(Br)cn1>>CCOC(=O)c1cccc(Sc2c(C)n(-c3cnn(CC(F)(F)F)c3)c3cc(Cl)ccc23)c1 -US20090264445A1,2,CCCOC(=O)C=C(CN[C@@H](CC(C)(F)F)C(=O)OC)Oc1ccccc1Cl>>COC(=O)[C@H](CC(C)(F)F)N1CC(Oc2ccccc2Cl)=CC1=O -US05260319,6,COC(OC)c1ccsc1Cc1ccccc1F>>O=Cc1ccsc1Cc1ccccc1F -US04000275,1,CC1OC1CCBr.O=c1c2ccc(Cl)cc2nc2[nH]c3ccccc3n12>>CC1OC1CCn1c2ccccc2n2c(=O)c3ccc(Cl)cc3nc12 -US05128369,1,CC(=O)CC1OCCc2ccccc21.CC(N)C(O)c1ccc(O)cc1>>CC(CC1OCCc2ccccc21)NC(C)C(O)c1ccc(O)cc1 -US20030083359A1,1,N[C@H]1CCCc2ccccc21.O=Cc1ccc(Br)cc1>>Brc1ccc(CN[C@H]2CCCc3ccccc32)cc1 -US20110098275A1,2,C1CC(N2CCOCC2)CCN1.CCc1nccc(-c2ccc(C(=O)O)c(Cl)c2)c1C#Cc1ccc(N)nc1>>CCc1nccc(-c2ccc(C(=O)N3CCC(N4CCOCC4)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 -US06096780,6,COC(=O)C1=Cc2cc(Br)ccc2CCC1>>O=C(O)C1=Cc2cc(Br)ccc2CCC1 -US06800651B2,2,N#Cc1ccccc1Oc1ccc(NCc2cccnc2)cc1.O=S(=O)(Cl)CC(F)(F)F>>N#Cc1ccccc1Oc1ccc(N(Cc2cccnc2)S(=O)(=O)CC(F)(F)F)cc1 -US20040176446A1,3,C[Si](C)(C)C#N.FC(F)(F)Oc1ccc(OCc2ccc(Br)cc2)c(CBr)c1>>N#CCc1cc(OC(F)(F)F)ccc1OCc1ccc(Br)cc1 -US20070197626A1,1,CC(C)(C)OC(=O)CBr.CCOC(=O)Cc1ccc(O)c(OCC)c1>>CCOC(=O)Cc1ccc(OCC(=O)OC(C)(C)C)c(OCC)c1 -US20110086834A1,1,CN1CC2(CNc3cc(O)ccc32)C1.Nc1ncc(Cl)c(Cl)n1>>CN1CC2(C1)CN(c1nc(N)ncc1Cl)c1cc(O)ccc12 -US20110212918A1,9,O=S(=O)(Nc1ccc2c(c1)B(O)OC2)c1ccc(O)cc1CBr.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1cc(O)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2 -US07863269B2,3,CON(C)C(=O)c1cc(NC(=O)C(F)(F)F)cc(S(F)(F)(F)(F)F)c1.C[Mg+]>>CC(=O)c1cc(NC(=O)C(F)(F)F)cc(S(F)(F)(F)(F)F)c1 -US06169087A,6,COc1ccc(-n2nc(NC(=O)OC(C)(C)C)c3csc(N)c3c2=O)cc1>>COc1ccc(-n2nc(N)c3csc(N)c3c2=O)cc1 -US07244730B2,9,CCOc1cc(CN(CC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC(C)(C)C)c(Br)cc1C(=O)NC.[C-]#N>>CCOc1cc(CN(CC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC(C)(C)C)c(C#N)cc1C(=O)NC -US20130303508A1,2,NCc1ccn2ccnc2c1.O=C=Nc1ccc(Br)cc1>>O=C(NCc1ccn2ccnc2c1)Nc1ccc(Br)cc1 -US20100004238A1,1,Clc1ncnc2cc[nH]c12.Nc1ccc(Oc2cccc3[nH]ccc23)c(Cl)c1>>Clc1cc(Nc2ncnc3cc[nH]c23)ccc1Oc1cccc2[nH]ccc12 -US20040167127A1,6,CCCn1nc(-c2ccc(OC)cc2)c2cccc(-c3ccc(F)cc3)c21>>CCCn1nc(-c2ccc(O)cc2)c2cccc(-c3ccc(F)cc3)c21 -US20070161640A1,6,O=C(OCc1ccccc1)[C@@H]1CC(=O)N1Cc1ccccc1>>O=C(O)[C@@H]1CC(=O)N1Cc1ccccc1 -US06344466B2,1,O=C(OCc1ccccc1)c1cc(O)cc(Cl)c1.OCCCBr>>O=C(OCc1ccccc1)c1cc(Cl)cc(OCCCO)c1 -US20130172328A1,7,O=[N+]([O-])c1ccc(N2CCn3c2nc2cccnc23)cc1>>Nc1ccc(N2CCn3c2nc2cccnc23)cc1 -US20050107435A1,1,CS(=O)(=O)OC[C@H]1CN(c2ccc(I)cc2)C(=O)O1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC[C@H]1CN(c2ccc(I)cc2)C(=O)O1 -US08188101B2,4,COc1cc(NC(=N)N)ccc1-n1cnc(C)c1.COc1cccc(CC(=O)C2CN(C(=O)OC(C)(C)C)CCC2=O)c1>>COc1cccc(Cc2nc(Nc3ccc(-n4cnc(C)c4)c(OC)c3)nc3c2CN(C(=O)OC(C)(C)C)CC3)c1 -US20050143422A1,9,CCOC(=O)c1oc2cccc(CBr)c2c1C>>CCOC(=O)c1oc2cccc(C)c2c1C -US20080119466A1,2,CC(C)(C)C(=O)OC(=O)C(C)(C)C.Nc1ncnc2c1ncn2-c1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1>>CC(C)(C)C(=O)Nc1ncnc2c1ncn2-c1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1 -US05169857,1,BrCc1ccccc1.CCOC(=O)c1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1>>CCOC(=O)c1c(C(C)C)nc(C(C)C)c(COCc2ccccc2)c1-c1ccc(F)cc1 -US09017673B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(CCN)OCC>>CCOC(CCNC(=O)OC(C)(C)C)OCC -US07687496B2,1,CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CC[Si](C)(C)CCCBr.c1nc[nH]n1>>CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CC[Si](C)(C)CCCn1cncn1 -US20070060567A1,6,COC(=O)c1ccc2c(c1)N(S(=O)(=O)c1cc(Cl)ccc1OC)CC2>>COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccc(C(=O)O)cc21 -US04968698,1,CCCCBr.O=Cc1cccc(O)c1>>CCCCOc1cccc(C=O)c1 -US20130096118A1,6,Cc1c(NC(=O)OCc2ccccc2)cccc1-c1cnc(C(N)=O)c2[nH]c3cc(Br)ccc3c12>>Cc1c(N)cccc1-c1cnc(C(N)=O)c2[nH]c3cc(Br)ccc3c12 -US20050154045A1,3,O=C(CC1CN2CCC1CC2)Nc1cccc(Br)c1.OCc1ccccc1B(O)O>>O=C(CC1CN2CCC1CC2)Nc1cccc(-c2ccccc2CO)c1 -US20100280268A1,6,COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(N(C)Cc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>CNc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1 -US04213985,1,C=C(C)CN1CCNCC1.O=C1Nc2cccnc2N(C(=O)CCCl)c2ccccc21>>C=C(C)CN1CCN(CCC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 -US20150152113A1,2,Cc1c(NN)ncnc1N1CCC(c2ccccc2)CC1.O=C(O)CC1CC1>>Cc1c(NNC(=O)CC2CC2)ncnc1N1CCC(c2ccccc2)CC1 -US20070254869A1,1,C1COCCN1.CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2ccc(Br)cc21>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2ccc(N3CCOCC3)cc21 -US05723497,7,CCCCCCC(O)CCCCCCCCCCC(=O)OC>>CCCCCCC(O)CCCCCCCCCCCO -US20100093703A1,1,CN.Ic1ccc(I)nn1>>CNc1ccc(I)nn1 -US04036951,1,CC1CCC(C(C)C)C(Br)C1.Nc1ccc(C(=O)[O-])c(O)c1>>CC1CCC(C(C)C)C(OC(=O)c2ccc(N)cc2O)C1 -US20110034451A1,1,Nc1nnc2ccc(Cl)nn12.OC1CCC1>>Nc1nnc2ccc(OC3CCC3)nn12 -US05780488,1,CN.N#Cc1ccc(Cn2cncc2C=O)cc1>>CNCc1cncn1Cc1ccc(C#N)cc1 -US08957070B2,2,Nc1cccc2cc(-c3ncns3)[nH]c12.O=S(=O)(Cl)c1cccs1>>O=S(=O)(Nc1cccc2cc(-c3ncns3)[nH]c12)c1cccs1 -US04886619,1,ClCc1ccccc1.Oc1ccc2cc(O)ccc2c1>>Oc1ccc2cc(OCc3ccccc3)ccc2c1 -US08114873B2,1,C1CCNCC1.O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1cccc(Br)c1>>O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1cccc(N2CCCCC2)c1 -US08314100B2,2,CC(=O)c1ccc(N2CCNCC2)cc1.CCOC(=O)Nc1nc2cc(OC)ccc2nc1OC>>COc1ccc2nc(OC)c(NC(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)nc2c1 -US08344000B2,6,Cc1cc2c(cc1F)oc(=O)n2C1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc2c(cc1F)oc(=O)n2C1CCNCC1 -US20040167158A1,1,Brc1ccsc1.CCN(CC)CCc1ccc2cc[nH]c2c1>>CCN(CC)CCc1ccc2ccn(-c3ccsc3)c2c1 -US04006160,9,[N-]=[N+]=[N-].[O-][n+]1c(Cl)ccc2ccccc21>>[N-]=[N+]=Nc1ccc2ccccc2[n+]1[O-] -US04940713,1,CC(=O)Nc1nc(N(C(C)=O)C(C)=O)c(CCC=O)c(=O)[nH]1.CCOC(=O)c1ccc(N)cc1>>CCOC(=O)c1ccc(NCCCc2c(N(C(C)=O)C(C)=O)nc(NC(C)=O)[nH]c2=O)cc1 -US08778926B2,1,C[C@@]1(C2CCNCC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1.Cc1cnc(Br)nc1>>Cc1cnc(N2CCC([C@]3(C)Cc4cc(C5=CCN(S(C)(=O)=O)CC5)ncc4O3)CC2)nc1 -US20090099199A1,2,CCC(CC)C(=O)Cl.Nc1ccc(N2CCC(C(c3ccccc3)c3ccccc3)CC2)c(F)c1>>CCC(CC)C(=O)Nc1ccc(N2CCC(C(c3ccccc3)c3ccccc3)CC2)c(F)c1 -US04125729,1,COC(=O)C(Br)c1ccc(Oc2ccc(Cl)cc2)cc1.Oc1ccc(Cl)c(Cl)c1>>COC(=O)C(Oc1ccc(Cl)c(Cl)c1)c1ccc(Oc2ccc(Cl)cc2)cc1 -US20050261273A1,2,CC(=O)O.CC(C)(C)c1cc(I)cc(C2(NCC(O)C(N)Cc3cc(F)cc(F)c3)CCCCC2)c1>>CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cc(I)cc(C(C)(C)C)c2)CCCCC1 -US08198282B2,3,C=CC(=O)OC(C)(C)C.Nc1cccnc1Br>>CC(C)(C)OC(=O)/C=C/c1ncccc1N -US20140357661A1,3,C=CC(=O)OC.O=Cc1ccc(Br)cc1F>>COC(=O)/C=C/c1ccc(C=O)c(F)c1 -US06100272,1,BrC1CCCC1.Cc1cc(N2CCCC2=O)ccc1-c1ccc(C(=O)N2CCc3cc4c(cc32)C2(CCNCC2)CO4)cc1>>Cc1cc(N2CCCC2=O)ccc1-c1ccc(C(=O)N2CCc3cc4c(cc32)C2(CCN(C3CCCC3)CC2)CO4)cc1 -US20110160185A9,1,Clc1nc(Cl)c2cc[nH]c2n1.NC1CCCC(C(=O)O)C1>>O=C(O)C1CCCC(Nc2nc(Cl)nc3[nH]ccc23)C1 -US07396847B2,9,[N-]=[N+]=NC[C@H]1CN(c2ccc(I)cc2)C(=O)O1>>NC[C@H]1CN(c2ccc(I)cc2)C(=O)O1 -US20090054483A1,3,C[Mg+].Fc1cccc(-c2ccnc3cc(Cl)ccc23)c1>>Cc1ccc2c(-c3cccc(F)c3)ccnc2c1 -US20060019997A1,2,CS(=O)(=O)Cl.OCc1cn(-c2cccc(Cl)c2)nn1>>CS(=O)(=O)OCc1cn(-c2cccc(Cl)c2)nn1 -US20130116243A1,1,BrC1CCC1.CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=O)CO4)cc2)CCC1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)N(C3CCC3)C(=O)CO4)cc2)CCC1 -US20080090834A1,1,Ic1ccc(-c2nc(-c3ccccn3)cn2-c2cccnc2)cc1.c1ccc2[nH]cnc2c1>>c1ccc(-c2cn(-c3cccnc3)c(-c3ccc(-n4cnc5ccccc54)cc3)n2)nc1 -US20110172276A1,2,CCOC(=O)c1c(O)cc(C)n(C)c1=O.Nc1ncc[nH]1>>Cc1cc(O)c(C(=O)Nc2ncc[nH]2)c(=O)n1C -US08426429B2,7,CCCNCc1cc(-c2ccccc2CCNS(=O)(=O)c2ccccc2)ccc1[N+](=O)[O-]>>CCCNCc1cc(-c2ccccc2CCNS(=O)(=O)c2ccccc2)ccc1N -US20050288287A1,2,CCOc1cc(C(C)(C)C#N)c(Cl)cc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.CON(C)C(=O)CN1CCNCC1>>CCOc1cc(C(C)(C)C#N)c(Cl)cc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N(C)OC)CC1 -US20080200475A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCc1cc2c(Cl)nc(Cl)nc2s1>>CCc1cc2c(N3CCN(C(=O)OC(C)(C)C)CC3)nc(Cl)nc2s1 -US08030354B2,6,COC(=O)c1ccc(OC2CCCCO2)c(C2=CCCC2(C)C)c1>>COC(=O)c1ccc(O)c(C2=CCCC2(C)C)c1 -US05811504,1,C=CCBr.O=C(O)c1ccc(O)cc1>>C=CCOc1ccc(C(=O)O)cc1 -US20100120775A1,1,COC(=O)c1ccc2cc(-c3ccc(O)cc3)ccc2n1.OCc1c(-c2c(Cl)cccc2Cl)noc1C1CCC1>>COC(=O)c1ccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CCC4)cc3)ccc2n1 -US20040132760A1,2,CN1[C@@H]2CC=C[C@@]1(O)CC2.O=C=NC(c1ccccc1)c1ccccc1>>CN1[C@@H]2CC=C[C@@]1(OC(=O)NC(c1ccccc1)c1ccccc1)CC2 -US20090036495A1,6,COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2COc2ccccc2Cl)cc1>>C[C@H](NC(=O)c1cc(Cl)ccc1COc1ccccc1Cl)c1ccc(C(=O)O)cc1 -US20060205788A1,9,COc1ccc(C2(C)CC(O)N(c3ccc(Cl)c(Cl)c3)C2=O)cc1OCCN1CCCCC1>>COc1ccc(C2(C)CCN(c3ccc(Cl)c(Cl)c3)C2=O)cc1OCCN1CCCCC1 -US07259177B2,7,CCOC(=O)c1nc(-c2ccc(C)cc2)oc1C>>Cc1ccc(-c2nc(CO)c(C)o2)cc1 -US20060148858A1,1,CCOc1cc(O)ccc1CCC(=O)OC.OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1OCc1ccccc1>>CCOc1cc(OCCCc2cn(-c3ccc(C(F)(F)F)cn3)nc2OCc2ccccc2)ccc1CCC(=O)OC -US20100093723A1,8,OCCCCN1CCOCC1>>O=CCCCN1CCOCC1 -US07641914B2,2,CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(=O)CCCOC1OCC(CN)O1.O=C(O)CN(CCCN(CCCNC(=O)C(F)(F)F)CCCNC(=O)C(F)(F)F)C(=O)C(F)(F)F>>CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(=O)CCCOC1OCC(CNC(=O)CN(CCCN(CCCNC(=O)C(F)(F)F)CCCNC(=O)C(F)(F)F)C(=O)C(F)(F)F)O1 -US20120316147A1,2,CC(C)(N)c1nccs1.O=C(O)c1ccc(N2CCCS2(=O)=O)c(OCC2CC2)n1>>CC(C)(NC(=O)c1ccc(N2CCCS2(=O)=O)c(OCC2CC2)n1)c1nccs1 -US20140303162A1,8,CC(C)C(O)c1c(Cl)ccnc1Cl>>CC(C)C(=O)c1c(Cl)ccnc1Cl -US08383584B2,2,C=CC1CC1(NC(=O)C1CC(O)CN1C(=O)OC(C)(C)C)C(=O)OCC.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>C=CC1CC1(NC(=O)C1CC(OC(=O)c2ccc([N+](=O)[O-])cc2)CN1C(=O)OC(C)(C)C)C(=O)OCC -US20140018537A1,1,CS(=O)(=O)c1ccc(OCc2ccc(C3CCNCC3)cn2)cc1.N#CBr>>CS(=O)(=O)c1ccc(OCc2ccc(C3CCN(C#N)CC3)cn2)cc1 -US08188092B2,3,COC(=O)C(C)c1ccc(B2OC(C)(C)C(C)(C)O2)c(Cl)c1.Cc1nc(C)c(-c2ccc(OS(=O)(=O)C(F)(F)F)cc2)nc1C(N)=O>>COC(=O)C(C)c1ccc(-c2ccc(-c3nc(C(N)=O)c(C)nc3C)cc2)c(Cl)c1 -US08524917B2,9,CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C=O)cc2n1Cc1ccccc1.NO>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(/C=N/O)cc2n1Cc1ccccc1 -US20150119362A1,1,CCOC(=O)Cc1ccc(N)cc1.Clc1nc(OC2CCCC2)nc2c1CCC2>>CCOC(=O)Cc1ccc(Nc2nc(OC3CCCC3)nc3c2CCC3)cc1 -US06407145B1,2,C=C(C)C(=O)O.COC(CN)OC>>C=C(C)C(=O)NCC(OC)OC -US20140155385A1,2,CCCC#CC(=O)O.Nc1nccn2c([C@@H]3CCCN3)nc(-c3ccc(C(=O)Nc4ccccn4)cc3)c12>>CCCC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(C(=O)Nc3ccccn3)cc2)c2c(N)nccn12 -US06001855,2,CCOC(=O)CCNC(=O)C1CCCNC1.Cc1nc(NC(=N)N)sc1C(=O)O>>CCOC(=O)CCNC(=O)C1CCCN(C(=O)c2sc(NC(=N)N)nc2C)C1 -US03978134,1,CC(C)CO.COC(=O)c1ccc(OCC=C(C)CBr)cc1>>COC(=O)c1ccc(OCC=C(C)COCC(C)C)cc1 -US05071465,2,CO.O=C(O)C1Oc2ccccc2C2(CC2)c2ccccc2O1>>COC(=O)C1Oc2ccccc2C2(CC2)c2ccccc2O1 -US20060270675A1,2,CCOC(=O)Cl.CC[C@H]1C[C@@H](NC(=O)OCc2ccccc2)c2cc(C(F)(F)F)ccc2N1>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@H](NC(=O)OCc2ccccc2)C[C@@H]1CC -US05703071,1,CC(C)c1ccc(CO)c(=O)c(O)c1.CCI>>CCOc1cc(C(C)C)ccc(CO)c1=O -US05627189,2,CCO.O=C(O)C=Cc1cccc(Br)c1>>CCOC(=O)C=Cc1cccc(Br)c1 -US20110263571A1,1,O=C(c1ccc(I)cc1)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1.O=C1N[C@H](COC(=O)c2ccccc2)CO1>>O=C(OC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C4CC4)cc3C3CC3)CC2)cc1)c1ccccc1 -US20080200468A1,6,COC(=O)c1cscc1NC(=O)CCc1ccc(-c2ccccc2)cc1>>O=C(CCc1ccc(-c2ccccc2)cc1)Nc1cscc1C(=O)O -US20110021479A1,2,COCC(=O)Cl.O=C(NC1CCNCC1)c1c[nH]c2c(-c3ccc(F)cc3OCC3CC3)ncnc12>>COCC(=O)N1CCC(NC(=O)c2c[nH]c3c(-c4ccc(F)cc4OCC4CC4)ncnc23)CC1 -US04753953,6,CC(=O)N(C)C1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1C>>CNC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1C -US06140265,3,Cc1ccc(B(O)O)cc1.N#Cc1ccccc1Cl>>Cc1ccc(-c2ccccc2C#N)cc1 -US20110152243A1,1,C1C[C@@H]2CNCCN2C1.CC(C)(C)OC(=O)Cc1nc(Cl)nc2cccc(F)c12>>CC(C)(C)OC(=O)Cc1nc(N2CCN3CCC[C@@H]3C2)nc2cccc(F)c12 -US20110172297A1,7,CCOC(=O)C1=C(c2ccc([Si](C)(C)C)cc2)CCOC1>>CCOC(=O)[C@@H]1COCC[C@@H]1c1ccc([Si](C)(C)C)cc1 -US05811439,1,Fc1ccccc1CBr.O=Cc1c[nH]c2ccccc12>>O=Cc1cn(Cc2ccccc2F)c2ccccc12 -US08293768B2,2,Cc1cc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C(=O)O.Cc1cnc(CN)cn1>>Cc1cnc(CNC(=O)c2sc(N3CCN(Cc4ccc(F)cc4)C3=O)cc2C)cn1 -US20150018547A1,1,COC(=O)Cc1csc2c(F)c(O)cc(C)c12.Cc1nc(C(F)(F)F)ccc1CO>>COC(=O)Cc1csc2c(F)c(OCc3ccc(C(F)(F)F)nc3C)cc(C)c12 -US20120289505A1,2,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(N)cc3)ccc2C1=O.COc1ccc(C(=O)Br)cc1>>COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=O)c4ccc(OC)cc4)cc3)ccc2C1=O -US20100168161A1,7,COc1ccccc1C(F)(F)COc1ccc(CC#N)cc1>>COc1ccccc1C(F)(F)COc1ccc(CCN)cc1 -US20120202783A1,1,Clc1cnnc(Cl)c1.O=C(c1cc(F)ccc1-n1nccn1)N1CC[C@H]2CN[C@H]2C1>>O=C(c1cc(F)ccc1-n1nccn1)N1CC[C@H]2CN(c3cnnc(Cl)c3)[C@H]2C1 -US20100152186A1,6,COC1CN(C(=O)OC(C)(C)C)CC1n1cnnc1-c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>COC1CNCC1n1cnnc1-c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20100081680A1,1,CI.O=S(=O)(c1ccc(Cl)cc1)N1C2CC(C3(O)CC3)CC1CC1(C2)OCCO1>>COC1(C2CC3CC4(CC(C2)N3S(=O)(=O)c2ccc(Cl)cc2)OCCO4)CC1 -US20150087631A1,1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.OC[C@@H]1CCCN1>>c1ccc2oc(-c3cnc4ccc(OC[C@@H]5CCCN5)nn34)cc2c1 -US04324786,2,CC(C)N(C1=Nc2ncccc2NN1)C(C)C.CCC(=O)OC(=O)CC>>CCC(=O)N1NC(N(C(C)C)C(C)C)=Nc2ncccc21 -US07919502B2,2,NCc1cccc(Cl)c1.O=C(O)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1>>O=C(NCc1cccc(Cl)c1)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1 -US20110053931A1,3,Ic1ccccn1.OB(O)c1cccnc1F>>Fc1ncccc1-c1ccccn1 -US20110076291A1,6,CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CCN(CCOC4CCCCO4)CC3)ccc1-2>>CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CCN(CCO)CC3)ccc1-2 -US05314887,1,ClCCCCBr.OCc1ccccc1S>>OCc1ccccc1SCCCCCl -US20080076771A1,2,Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1.O=C(Cl)c1ccc(Nc2cnccn2)cc1>>O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cnccn2)cc1 -US20120252758A1,6,COc1ccc(F)cc1C(C)C(F)(F)F>>CC(c1cc(F)ccc1O)C(F)(F)F -US20070043048A1,3,CC1(C)CC(Nc2nccc(Cl)n2)CC(C)(C)N1.OB(O)c1ccc2ccccc2c1>>CC1(C)CC(Nc2nccc(-c3ccc4ccccc4c3)n2)CC(C)(C)N1 -US06900215B2,3,CC(C)(O)c1ccn2c(Br)cnc2n1.CC1(C)OB(c2ccc(F)c(-c3ccsc3C#N)c2)OC1(C)C>>CC(C)(O)c1ccn2c(-c3ccc(F)c(-c4ccsc4C#N)c3)cnc2n1 -US08470841B2,1,CC(=O)N[C@@H](C)COc1ccc(Oc2ccc(O)cc2)cc1.CC(C)I>>CC(=O)N[C@@H](C)COc1ccc(Oc2ccc(OC(C)C)cc2)cc1 -US04162328,2,C#CCOCCCCCCCCCCO.O=C(O)C1CC1>>C#CCOCCCCCCCCCCOC(=O)C1CC1 -US08129376B2,2,Fc1cc(OC2CNC2)cc(C(F)(F)F)c1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>O=C(NCC(=O)N1CC(Oc2cc(F)cc(C(F)(F)F)c2)C1)c1cc(-c2ccccc2)[nH]n1 -US04473395,2,CC(C)(C)O.Cc1ncc(-c2ccc(Cl)cc2)cc1C(=O)Cl>>Cc1ncc(-c2ccc(Cl)cc2)cc1C(=O)OC(C)(C)C -US05034417,7,CC(=O)c1ccc([N+](=O)[O-])c(Sc2ccc(F)cc2F)c1>>CC(=O)c1ccc(N)c(Sc2ccc(F)cc2F)c1 -US20150119385A1,6,CCOC(=O)C(C)(C)NCCNC(=O)OC(C)(C)C>>CCOC(=O)C(C)(C)NCCN -US20100029609A1,2,CC(C)(N)CN.Cc1cc(S(=O)(=O)Nc2cccc(-c3ccc(C(=O)O)cc3)c2)c(C)cc1Cl>>Cc1cc(S(=O)(=O)Nc2cccc(-c3ccc(C(=O)NCC(C)(C)N)cc3)c2)c(C)cc1Cl -US20100286275A1,6,COC(=O)c1cccc(-c2cccc(NCCNC(=O)OC(C)(C)C)c2)c1>>COC(=O)c1cccc(-c2cccc(NCCN)c2)c1 -US08927587B2,4,CC(C)(C)OC(=O)N[C@@H](CCCOCc1ccccc1)C(=O)O.CC(C)(C)c1ccc(N)c(N)c1>>CC(C)(C)OC(=O)N[C@@H](CCCOCc1ccccc1)c1nc2cc(C(C)(C)C)ccc2[nH]1 -US20120322788A1,7,[N-]=[N+]=NCC(=O)c1ccc(O)c2[nH]c(=O)sc12>>[N-]=[N+]=NC[C@H](O)c1ccc(O)c2[nH]c(=O)sc12 -US20100286114A1,1,C1CC2(CCN1)OCCO2.Cn1c(-c2cccc(Br)c2)nc2ccccc21>>Cn1c(-c2cccc(N3CCC4(CC3)OCCO4)c2)nc2ccccc21 -US20110319393A1,2,O=C(O)CCCN1CCN(c2nnc(C(F)(F)F)s2)CC1.O=[N+]([O-])c1ccc(NC2CCNCC2)cc1C(F)(F)F>>O=C(CCCN1CCN(c2nnc(C(F)(F)F)s2)CC1)N1CCC(Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1 -US06387928B1,1,CCOC(=O)C(=CNC1CC1)C(=O)c1cc([N+](=O)[O-])c(F)c(Cl)c1F>>CCOC(=O)c1cn(C2CC2)c2c(Cl)c(F)c([N+](=O)[O-])cc2c1=O -US20140213571A1,1,OCCBr.Oc1ccc(Br)cc1-c1cc2ccccc2[nH]1>>BrCCOc1ccc(Br)cc1-c1cc2ccccc2[nH]1 -US04709081,1,CC(=O)OCc1cccc(Br)c1.Oc1ccccc1>>CC(=O)OCc1cccc(Oc2ccccc2)c1 -US07786046B2,2,CCOC(=O)C(NC(=O)c1ccc(F)cc1C(F)(F)F)C(O)C(F)(F)F.CN>>CNC(=O)C(NC(=O)c1ccc(F)cc1C(F)(F)F)C(O)C(F)(F)F -US20040204369A1,8,O=C(NC[C@H]1CCCN(CC2CCCCC2)C1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C1C[C@@H](C(=O)N2CCC[C@@H]2C(=O)NC[C@H]2CCCN(CC3CCCCC3)C2)N(C(=O)CC(c2ccccc2)(c2ccccc2)c2ccccc2)C1 -US20050090529A1,4,N=C(N)c1ccncc1.O=C(CBr)c1nn(C2CCCCO2)c2ccc(Br)cc12>>Brc1ccc2c(c1)c(-c1cnc(-c3ccncc3)[nH]1)nn2C1CCCCO1 -US20120316147A1,2,NC(=O)[C@@H](N)CC1CC1.O=C(O)c1ccc(C2CCOC2)c(OCC2CC2)n1>>NC(=O)[C@H](CC1CC1)NC(=O)c1ccc(C2CCOC2)c(OCC2CC2)n1 -US20150218150A1,3,CC1(C)OB(c2ccnc(N)c2)OC1(C)C.CN1Cc2cc(-c3ccc(I)s3)ccc2C1=O>>CN1Cc2cc(-c3ccc(-c4ccnc(N)c4)s3)ccc2C1=O -US04495184,2,CC1CN(CC(C)C(O)c2ccc(C(C)(C)C)cc2)CC(C)O1.O=C=Nc1ccc(Cl)c(Cl)c1>>CC1CN(CC(C)C(OC(=O)Nc2ccc(Cl)c(Cl)c2)c2ccc(C(C)(C)C)cc2)CC(C)O1 -US05910506,7,COC(=O)Cc1nc(C(C)C)c(Sc2cc(Cl)cc(Cl)c2)n1C>>CC(C)c1nc(CCO)n(C)c1Sc1cc(Cl)cc(Cl)c1 -US20020198197A1,2,CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)c(C(F)(F)F)cc1N.CN(C)Cc1cnnn1-c1cccc(C(=O)CC(=O)OC(C)(C)C)c1>>CN(C)Cc1cnnn1-c1cccc(C(=O)CC(=O)Nc2cc(C(F)(F)F)c(N3CCOCC3)cc2NC(=O)OC(C)(C)C)c1 -US08063046B2,2,COc1ccc(C(N)=O)cc1C(=O)O.Nc1cccc(Cl)c1>>COc1ccc(C(N)=O)cc1C(=O)Nc1cccc(Cl)c1 -US20100234351A1,1,CC(C)(C)NC(=O)c1cccc(Oc2ccc(Nc3ncnc4c3C=C(C=O)CCN4)cc2Cl)c1.COC1CCNCC1>>COC1CCN(CC2=Cc3c(ncnc3Nc3ccc(Oc4cccc(C(=O)NC(C)(C)C)c4)c(Cl)c3)NCC2)CC1 -US20120129840A1,3,CC1(C)OB(c2ccc3ncsc3c2)OC1(C)C.CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1Cl>>CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2ncsc2c1 -US08173824B2,7,CC(=O)[C@H]1CC[C@H]2/C(=C/Br)CCC[C@]12C>>C[C@@H](O)[C@H]1CC[C@H]2/C(=C/Br)CCC[C@@]21C -US20060074064A1,7,CCOC(=O)c1cn2c(n1)sc1cc(F)ccc12>>OCc1cn2c(n1)sc1cc(F)ccc12 -US08664228B2,9,COC(=O)C(CCCc1ccc(OC)cc1)NC(=O)OC(C)(C)C.N>>COc1ccc(CCCC(NC(=O)OC(C)(C)C)C(N)=O)cc1 -US20100076014A1,6,COC(=O)C(C)(CO)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1>>CC(CO)(C(=O)O)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 -US20030208079A1,6,COc1cc2c(cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1)C(c1ccccc1)(C(F)(F)F)OC2>>COc1cc2c(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)C(c1ccccc1)(C(F)(F)F)OC2 -US20140066426A1,3,Cc1c(B2OC(C)(C)C(C)(C)O2)c(C(=O)N(C)CC(C)(C)C)n(Cc2ccccc2)c1C(F)(F)F.FC(F)(F)COc1ccc(Br)cc1>>Cc1c(-c2ccc(OCC(F)(F)F)cc2)c(C(=O)N(C)CC(C)(C)C)n(Cc2ccccc2)c1C(F)(F)F -US03940395,1,COCCNc1cc(Cl)nc(-c2ccc(OC)cc2)n1.Sc1ccc(Cl)cc1>>COCCNc1cc(Sc2ccc(Cl)cc2)nc(-c2ccc(OC)cc2)n1 -US20080269293A1,2,Cc1cc(Oc2ccccc2N=C=O)n(-c2ccccc2Cl)n1.Nc1ccc(C2CC2)cc1>>Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(C3CC3)cc2)n(-c2ccccc2Cl)n1 -US06756497B1,9,CCOC(=O)c1cc(Cl)c(S(C)(=O)=O)c(-c2cc(C)no2)c1C>>CCOC(=O)c1ccc(S(C)(=O)=O)c(-c2cc(C)no2)c1C -US07834062B2,1,CC(C)(C)N.CC(C)(C)c1cc(C(C)(C)C)c(-c2ccc(Cl)cc2)c(O)c1C=O>>CC(C)(C)NCc1c(C(C)(C)C)cc(C(C)(C)C)c(-c2ccc(Cl)cc2)c1O -US20120232056A1,1,COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(Cl)nc2c1.Cc1ccccc1N>>COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(Nc3ccccc3C)nc2c1 -US05281593,8,OCc1cccc2cc[nH]c12>>O=Cc1cccc2cc[nH]c12 -US04264608,1,COc1ccnc(CCl)c1.NCCS>>COc1ccnc(CSCCN)c1 -US06486155B1,2,COC(=O)c1c(-c2cc(Br)c(OC)c(OC)c2)c2cc(OC)c(OC)cc2c(=O)n1-c1cccc(N)c1.O=CO>>COC(=O)c1c(-c2cc(Br)c(OC)c(OC)c2)c2cc(OC)c(OC)cc2c(=O)n1-c1cccc(NC=O)c1 -US20080033001A1,1,C1=COCCC1.O=C1c2ccccc2C(=O)N1CC(O)c1cc2cccnc2[nH]1>>O=C1c2ccccc2C(=O)N1CC(OC1CCCCO1)c1cc2cccnc2[nH]1 -US05753648,2,CN(C)CCCNc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cn1.Cc1ccc(F)cc1C(=O)Cl>>Cc1ccc(F)cc1C(=O)N(CCCN(C)C)c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cn1 -US20140296226A1,3,CC1(C)OB(C2=CCCOC2)OC1(C)C.NC1=N[C@@]2(CCO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1Oc1ncc(Br)cc12>>NC1=N[C@@]2(CCO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1Oc1ncc(C3=CCCOC3)cc12 -US20130296312A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=[N+]([O-])c1cccc(Br)c1>>CC(C)(C)OC(=O)N1CC=C(c2cccc([N+](=O)[O-])c2)CC1 -US20090186879A1,8,COc1nc(C)c(N2CCCn3c2nc2c(Cl)ccc(CO)c23)c(C)n1>>COc1nc(C)c(N2CCCn3c2nc2c(Cl)ccc(C=O)c23)c(C)n1 -US05166180,1,CNC.COc1cccc(F)c1C(=O)NC(=O)Nc1cccc(C(F)(F)F)c1>>COc1cccc(N(C)C)c1C(=O)NC(=O)Nc1cccc(C(F)(F)F)c1 -US07855292B2,6,COC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12>>O=C(N[C@@H](Cc1ccc(Cl)c(Cl)c1)C(=O)O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 -US05302621,2,C[C@]12CC[C@H]3[C@@H](CC=C4NC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)O.Cc1ccc(C[C@H](N)c2ccccc2)cc1>>Cc1ccc(C[C@H](NC(=O)[C@H]2CC[C@H]3[C@@H]4CC=C5NC(=O)CC[C@]5(C)[C@H]4CC[C@]23C)c2ccccc2)cc1 -US20060287536A1,2,CCC(O)(CC)COc1ccc(C(CC)(CC)c2cc(C)c(C(=O)O)s2)cc1C.COC(=O)CN>>CCC(O)(CC)COc1ccc(C(CC)(CC)c2cc(C)c(C(=O)NCC(=O)OC)s2)cc1C -US20110306722A1,2,O=C(O)CC[C@@H](C(=O)OCc1ccccc1)n1c2ccccc2c2ccccc21.OCCO>>O=C(CC[C@@H](C(=O)OCc1ccccc1)n1c2ccccc2c2ccccc21)OCCO -US20120016029A1,2,CCO.O=C(O)Cc1cc(OCc2ccccc2)cc(C(F)(F)F)c1>>CCOC(=O)Cc1cc(OCc2ccccc2)cc(C(F)(F)F)c1 -US20140179714A1,1,CN(C)C.COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nn(Cc3ccc(CBr)cc3)c(=O)n2C1c1ccc(C#N)cc1>>COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nn(Cc3ccc(C[N+](C)(C)C)cc3)c(=O)n2C1c1ccc(C#N)cc1 -US04734419,1,CCOC(=O)CBr.NC(=O)c1ccccc1N>>CCOC(=O)CNc1ccccc1C(N)=O -US20100168062A1,2,C1COCCN1.O=C(O)c1ccc(Br)cc1F>>O=C(c1ccc(Br)cc1F)N1CCOCC1 -US20070265265A1,2,COC(=O)c1sc(N)nc1-c1ccc(C(=O)NC2CC2)cc1.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>COC(=O)c1sc(NC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)nc1-c1ccc(C(=O)NC2CC2)cc1 -US20120225908A1,7,CC(C)(CO)CCCCCC(=O)CCCCCC(C)(C)CO>>CC(C)(CO)CCCCCC(O)CCCCCC(C)(C)CO -US20130172384A1,3,CC1(C)OB(c2ccc3occc3c2)OC1(C)C.Cn1nc(-c2ccc(Br)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O>>Cn1nc(-c2ccc(-c3ccc4occc4c3)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O -US20150284386A1,2,CC1(C)C(=O)N(C2CC2)c2cc(N)ncc21.Cc1ncc(C(=O)O)cn1>>Cc1ncc(C(=O)Nc2cc3c(cn2)C(C)(C)C(=O)N3C2CC2)cn1 -US20060030709A1,2,O=C(O)Cn1cnc2c(NC(=O)OC(c3ccccc3)c3ccccc3)ncnc21.O=C1CNCCN1S(=O)(=O)c1nc2ccccc2s1>>O=C(Nc1ncnc2c1ncn2CC(=O)N1CCN(S(=O)(=O)c2nc3ccccc3s2)C(=O)C1)OC(c1ccccc1)c1ccccc1 -US20100130737A1,7,COC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)OC(C)(C)C -US09139589B2,3,CC(=O)Nc1cc(-c2nc(Br)c(-c3nccn3COCC[Si](C)(C)C)s2)ccn1.Cn1cc(B2OC(C)(C)C(C)(C)O2)c(C(F)(F)F)n1>>CC(=O)Nc1cc(-c2nc(-c3cn(C)nc3C(F)(F)F)c(-c3nccn3COCC[Si](C)(C)C)s2)ccn1 -US20040082789A1,3,Brc1ccccc1.O=Cc1sccc1B(O)O>>O=Cc1sccc1-c1ccccc1 -US09023873B2,1,CI.COc1c(C(=O)Nc2c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Br)cccc1N(C)C(=O)c1ccncc1>>COc1c(C(=O)N(C)c2c(Br)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Br)cccc1N(C)C(=O)c1ccncc1 -US20140343083A1,1,BrC1CCC1.Oc1ccc(Br)cc1>>Brc1ccc(OC2CCC2)cc1 -US20070135357A1,7,CC(=O)Sc1ccc(C(=O)O)cc1>>CC(=O)Sc1ccc(CO)cc1 -US03970682,7,CCCC1=C(CC(=O)OC)CCC1=O>>CCCC1C(=O)CCC1CC(=O)OC -US05242925,1,COC(=O)c1ccc2[nH]cc(CCCCCl)c2c1.c1cc2c(cc1N1CCNCC1)OCCO2>>COC(=O)c1ccc2[nH]cc(CCCCN3CCN(c4ccc5c(c4)OCCO5)CC3)c2c1 -US04017522,2,CC(C)(C)C(=O)Cl.CCCCCCCCCCCC(=O)N(C)CCO>>CCCCCCCCCCCC(=O)N(C)CCOC(=O)C(C)(C)C -US20060189629A1,1,Nc1cccc(-n2cnc3cc(C(=O)NCc4cccnc4)ccc32)c1.O=Cc1ccc(Cl)cc1>>O=C(NCc1cccnc1)c1ccc2c(c1)ncn2-c1cccc(NCc2ccc(Cl)cc2)c1 -US08202513B2,1,C1CCNCC1.COc1c(Cl)c(C)c(C(C)=O)c(OCCBr)c1OCCC(C)c1ccc(F)cc1>>COc1c(Cl)c(C)c(C(C)=O)c(OCCN2CCCCC2)c1OCCC(C)c1ccc(F)cc1 -US20050054658A1,6,CC(C)(C)[Si](C)(C)OC(COC1CCC(OCc2ccccc2)CC1F)c1ccccc1>>CC(C)(C)[Si](C)(C)OC(COC1CCC(O)CC1F)c1ccccc1 -US20100240656A1,2,CS(=O)(=O)Cl.Cc1c(N)c(C(N)=O)nn1Cc1cc2c(cc1Br)OCO2>>Cc1c(NS(C)(=O)=O)c(C(N)=O)nn1Cc1cc2c(cc1Br)OCO2 -US20050143381A1,10,Cc1ccc(-c2ccon2)cc1.O=C1CCC(=O)N1Br>>BrCc1ccc(-c2ccon2)cc1 -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(Oc3cnc(CN)cn3)cc(C)c21>>Cc1cc(Oc2cnc(CN)cn2)cc2c1C(CC(=O)O)OB2O -US07378417B2,2,CC(C)(CO)NS(=O)(=O)c1cccc(N)c1.Cc1cc(-c2ccc(Cl)cc2)nc2c(C(=O)O)cnn12>>Cc1cc(-c2ccc(Cl)cc2)nc2c(C(=O)Nc3cccc(S(=O)(=O)NC(C)(C)CO)c3)cnn12 -US20130005710A1,7,COc1cc(OC)cc(C2CNC(=O)CO2)c1>>COc1cc(OC)cc(C2CNCCO2)c1 -US20140056849A1,1,CC(Cl)OC(=O)C(NC(=O)OC(C)(C)C)C(C)C.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2cn(C(C)OC(=O)C(NC(=O)OC(C)(C)C)C(C)C)c3ncc(-c4ccc(Cl)cc4)cc23)c1F -US20090247526A1,6,CCOC(=O)Cc1cc(Nc2nc(CCc3ccccc3)cs2)ncc1Br>>O=C(O)Cc1cc(Nc2nc(CCc3ccccc3)cs2)ncc1Br -US07678909B1,7,Cn1c(=O)c([N+](=O)[O-])c(N)c2cccnc21>>Cn1c(=O)c(N)c(N)c2cccnc21 -US05866684,6,Cc1ccccc1C[C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1)C(C)(C)C>>Cc1ccccc1C[C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@@H](N)CC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1)C(C)(C)C -US08026257B2,9,CC(C)(C)OC(=O)N1CCC(COC(C(N)=O)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(COC(C#N)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1 -US20110003820A1,2,Cc1nnc2n1CCNC2.O=C(O)c1cc2ncc(Cl)cn2n1>>Cc1nnc2n1CCN(C(=O)c1cc3ncc(Cl)cn3n1)C2 -US08288549B2,1,NC(=O)C(N)Cc1ccccc1.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>NC(=O)C(Cc1ccccc1)Nc1nc2ccc(Cl)cc2cc1C(=O)O -US20120046269A1,6,NC(=O)c1cccc2c(NCc3cccc(Nc4ncc(CN5C(=O)c6ccccc6C5=O)s4)c3)ncnc12>>NCc1cnc(Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)s1 -US20070219183A1,2,CC(=O)OC(C)=O.CCOC(=O)c1cnn2c1NCC=C2c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1>>CCOC(=O)c1cnn2c1N(C(C)=O)CC=C2c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1 -US20050090529A1,2,CCN(Cc1cncc(-c2ccc3c(c2)c(-c2ncc(C(=O)O)[nH]2)nn3C2CCCCO2)c1C)C(=O)OC(C)(C)C.C[C@H]1CNC[C@@H](C)O1>>CCN(Cc1cncc(-c2ccc3c(c2)c(-c2ncc(C(=O)N4C[C@H](C)O[C@H](C)C4)[nH]2)nn3C2CCCCO2)c1C)C(=O)OC(C)(C)C -US05821261,2,CC(C)(C)OC(=O)[C@@H]1C[C@H](CO)CN1C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)[C@@H]1C[C@H](COS(C)(=O)=O)CN1C(=O)OC(C)(C)C -US08173676B2,6,CCSCC(O)(C(Nc1cccc2nc(C)ccc12)c1ccc(F)c(OC)c1F)C(F)(F)F>>CCSCC(O)(C(Nc1cccc2nc(C)ccc12)c1ccc(F)c(O)c1F)C(F)(F)F -US20130310379A1,6,COC(=O)c1ccc(Oc2ccc(I)cn2)cc1>>O=C(O)c1ccc(Oc2ccc(I)cn2)cc1 -US20150087663A1,1,C[C@H](N)c1nc2cccc(-c3cnn(C)c3)c2c(=O)n1C1CC1.Cc1noc(-c2c(N)ncnc2Cl)n1>>Cc1noc(-c2c(N)ncnc2N[C@@H](C)c2nc3cccc(-c4cnn(C)c4)c3c(=O)n2C2CC2)n1 -US04560789,3,CC(=O)Oc1ccccc1>>CC(=O)c1ccc(O)cc1 -US07452992B2,2,CC(C)(C)C(=O)Cl.Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2ccccc2)CNCCO1>>Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2ccccc2)CN(C(=O)C(C)(C)C)CCO1 -US06825188B2,6,COC(=O)CC1Cc2ccc(OCCCNc3ncccn3)cc2CNC1=O>>O=C(O)CC1Cc2ccc(OCCCNc3ncccn3)cc2CNC1=O -US20030220241A1,1,N#Cc1ccc(CBr)cc1F.c1c[nH]cn1>>N#Cc1ccc(Cn2ccnc2)cc1F -US07919621B2,1,CCCCC(CC)COC(=O)CCS.Ic1ccc2c(-c3ccccc3)cc3nncn3c2c1>>CCCCC(CC)COC(=O)CCSc1ccc2c(-c3ccccc3)cc3nncn3c2c1 -US08383608B2,1,C=CCOCC1(c2cccc(C)c2)NC(=O)NC1=O.N#Cc1ccc(Br)cc1C(F)(F)F>>C=CCOCC1(c2cccc(C)c2)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O -US07435744B2,2,Cc1ccc(CC2CCNCC2)cc1.O=C1COc2cc(NC(=O)C(=O)O)ccc2N1>>Cc1ccc(CC2CCN(C(=O)C(=O)Nc3ccc4c(c3)OCC(=O)N4)CC2)cc1 -US04882338,1,CC(C)(C)C(=O)OCCl.COc1cc2ccnc(CSc3nc4ccccc4[nH]3)c2cc1OCC(F)(F)F>>COc1cc2ccnc(CSc3nc4ccccc4n3COC(=O)C(C)(C)C)c2cc1OCC(F)(F)F -US20070225232A1,7,CC(C)(C)NC(=O)c1ccc(C2=CCCn3cncc32)cc1>>CC(C)(C)NC(=O)c1ccc(C2CCCn3cncc32)cc1 -US20070027125A1,3,Cn1c(C#N)ccc1B(O)O.N#CNc1ccc(Br)cc1>>Cn1c(C#N)ccc1-c1ccc(NC#N)cc1 -US20100184805A1,6,COC(=O)NCCO[C@@H](c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)O[C@@H]2CN(C(=O)OCc3ccccc3)CC[C@H]2CC(C)C)C1>>COC(=O)NCCO[C@@H](c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)O[C@@H]2CNCC[C@H]2CC(C)C)C1 -US07074800B1,1,COc1cc2c(Oc3ccc4[nH]ccc4c3)ncnc2cc1O.OCCN1CCOCC1>>COc1cc2c(Oc3ccc4[nH]ccc4c3)ncnc2cc1OCCN1CCOCC1 -US20150005277A1,6,CC(C)(C)OC(=O)N1CCCC(n2nc(-c3ccc(Oc4ccccc4)cc3)c(C(N)=O)c2N)C1>>NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn(C2CCCNC2)c1N -US20150099777A1,3,CCOc1c(C=O)cc(Br)c(-c2ccc(F)cc2)c1F.OB(O)C1CC1>>CCOc1c(C=O)cc(C2CC2)c(-c2ccc(F)cc2)c1F -US20100041892A1,1,BrCc1ccccc1.COCCOc1ccc(C(C)=O)c(O)c1>>COCCOc1ccc(C(C)=O)c(OCc2ccccc2)c1 -US20050020606A1,1,Cc1cc(OCC(F)(F)F)c(NC(=O)CBr)c(OCC(F)(F)F)n1.Fc1ccc2nc(SCCN3CCNCC3)[nH]c2c1>>Cc1cc(OCC(F)(F)F)c(NC(=O)CN2CCN(CCSc3nc4ccc(F)cc4[nH]3)CC2)c(OCC(F)(F)F)n1 -US04725680,2,CC(Cl)OC(=O)OCc1ccccc1.O=C(O)[C@@H]1CCCN1>>O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1 -US20110105758A1,6,CCOC(=O)C1=C(c2ccccc2)CN(Cc2ccccc2)C1>>O=C(O)C1=C(c2ccccc2)CN(Cc2ccccc2)C1 -US08288384B2,1,CC(C)(C)OC(=O)N1CCC(c2nc(CCl)cs2)CC1.CSc1ncc(O)cn1>>CSc1ncc(OCc2csc(C3CCN(C(=O)OC(C)(C)C)CC3)n2)cn1 -US20070213348A1,3,N#Cc1ccc(B(O)O)cc1.Oc1ccc(C(=C2CCCCCCC2)c2ccc(Br)cc2)cc1>>N#Cc1ccc(-c2ccc(C(=C3CCCCCCC3)c3ccc(O)cc3)cc2)cc1 -US04618610,1,CCC(=O)c1ccccc1O.ClCc1ccccc1>>CCC(=O)c1ccccc1OCc1ccccc1 -US04904690,9,N.O=C(O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12>>NC(=O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12 -US08809525B2,3,CC1(C)OB(c2cccc(NS(C)(=O)=O)c2)OC1(C)C.Nc1nnc(Br)c(-c2ccccc2)n1>>CS(=O)(=O)Nc1cccc(-c2nnc(N)nc2-c2ccccc2)c1 -US06117893,7,CCOC(=O)c1cc2cccnc2n1C>>Cn1c(CO)cc2cccnc21 -US20100120741A1,1,CN1CCNCC1.Clc1ccc2nc(Cl)c3nc[nH]c3c2c1>>CN1CCN(c2nc3ccc(Cl)cc3c3[nH]cnc23)CC1 -US06613770B1,1,CC(C)N1CCNCC1.COC(=O)c1c(CBr)c(-c2ccccc2)nc2ccccc12>>COC(=O)c1c(CN2CCN(C(C)C)CC2)c(-c2ccccc2)nc2ccccc12 -US20080306120A1,2,CCn1cc(-c2ccnc3[nH]c(C4=CCNCC4)cc23)c(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1.CN(C)CC(=O)O>>CCn1cc(-c2ccnc3[nH]c(C4=CCN(C(=O)CN(C)C)CC4)cc23)c(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1 -US20140249132A1,1,COc1c(C(C)Cl)cc(Cl)c(C)c1-c1ccnc(C#N)c1.Cc1n[nH]c2ncnc(N)c12>>COc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C)c1-c1ccnc(C#N)c1 -US20080167307A1,9,CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ncc(C(N)=O)cc1Cl>>CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ncc(C#N)cc1Cl -US08273770B2,1,Brc1ccc2[nH]ncc2c1.ClCCBr>>ClCCn1ncc2cc(Br)ccc21 -US04051261,6,CC(=O)OCc1ccc(C(=O)C(C)(C)C)cc1>>CC(C)(C)C(=O)c1ccc(CO)cc1 -US20100168101A1,6,COC(=O)c1ccc(C(=O)NCc2ccc(C(=O)NN=C3C(=O)Nc4ccc(I)cc43)cc2)cc1>>O=C1Nc2ccc(I)cc2C1=NNC(=O)c1ccc(CNC(=O)c2ccc(C(=O)O)cc2)cc1 -US20050096337A1,2,CCOC(=O)C(C)(C)Oc1cc(CCN)cc(OC)c1.Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1C(=O)O>>CCOC(=O)C(C)(C)Oc1cc(CCNC(=O)c2ccc(-c3ccc(C(F)(F)F)cc3)nc2C)cc(OC)c1 -US04225606,2,CCOC(=O)N1CCC(Nc2ccc(Cl)cc2)CC1.O=C(Cl)Cc1ccccc1>>CCOC(=O)N1CCC(N(C(=O)Cc2ccccc2)c2ccc(Cl)cc2)CC1 -US05880130,1,CCOC(=O)CBr.O=[N+]([O-])c1cccc(O)c1>>CCOC(=O)COc1cccc([N+](=O)[O-])c1 -US07727997B2,2,CCc1cccc(CNC[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)c1.COC(=O)CCc1cnc(-c2cccc(C(=O)O)c2)o1>>CCc1cccc(CNC[C@@H](O)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cccc(-c3ncc(CCC(=O)OC)o3)c2)c1 -US07935724B2,2,COC(=O)c1ccc(NC(=O)Cc2ccccc2)s1.NO>>O=C(Cc1ccccc1)Nc1ccc(C(=O)NO)s1 -US20040192688A1,1,COc1ccc(N)cc1.ClCCCOc1ccc2ccccc2c1>>COc1ccc(NCCCOc2ccc3ccccc3c2)cc1 -US04310544,1,ClCc1ccc(-c2ccc(Cl)cc2)cc1.O=C(O)C(O)c1ccccc1>>O=C(O)C(OCc1ccc(-c2ccc(Cl)cc2)cc1)c1ccccc1 -US20120071505A1,1,CC1OCCC1S(=O)(=O)c1ccncc1C(=O)O.COCCCBr>>COCCCOC(=O)c1cnccc1S(=O)(=O)C1CCOC1C -US20130225524A1,3,Nc1cc(Br)cc([N+](=O)[O-])c1.OB(O)c1ccoc1>>Nc1cc(-c2ccoc2)cc([N+](=O)[O-])c1 -US20140142097A1,2,CCNCCN(C)C.Nc1ncc(-c2ccc(C(=O)O)cc2)cc1C(=O)Nc1ccncc1>>CCN(CCN(C)C)C(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccncc3)c2)cc1 -US20060189577A1,3,CCc1c(I)[nH]c(C=O)c1C(=O)OCc1ccccc1.O=[N+]([O-])c1cccc(B(O)O)c1>>CCc1c(-c2cccc([N+](=O)[O-])c2)[nH]c(C=O)c1C(=O)OCc1ccccc1 -US04174317,1,CN(C)CCCN.O=Cc1ccc2c(c1)OCO2>>CN(C)CCCN=Cc1ccc2c(c1)OCO2 -US06030969,6,CC(C)c1ccc(C#C[Si](C)(C)C)cc1>>C#Cc1ccc(C(C)C)cc1 -US20100273770A1,6,CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCN(C(=O)OC(C)(C)C)C4CCCC(=O)O)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCNC4CCCC(=O)O)no2)cc1C#N -US20050090529A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1c(N)cncc1Br>>Cc1c(Br)cncc1NC(=O)OC(C)(C)C -US20150175602A1,2,CC(=O)OC(C)=O.CC(C)Nc1nc2c(nc1N1CCC(C(=O)c3cc(Cl)ccc3F)CC1)CCNC2>>CC(=O)N1CCc2nc(N3CCC(C(=O)c4cc(Cl)ccc4F)CC3)c(NC(C)C)nc2C1 -US08178522B2,2,Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)O.N[C@H]1CCOC1>>Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)N[C@H]1CCOC1 -US20150225389A1,6,COc1ccc(CC[C@@]2(C)C(=O)N(C(=O)N[C@H](C)c3ccccc3)[C@@H]2C(=O)OCc2ccccc2)cc1>>COc1ccc(CC[C@@]2(C)C(=O)N(C(=O)N[C@H](C)c3ccccc3)[C@@H]2C(=O)O)cc1 -US20100267696A1,6,CC(C)(C)OC(=O)N1CCCC(c2cc(C(=O)N3CCCCCC3)cs2)C1>>O=C(c1csc(C2CCCNC2)c1)N1CCCCCC1 -US08143251B2,2,CC(C)(C)OC(=O)[C@@H](N)C(C)(C)C.O=C(O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncsc6c5)CC4)n3n2)cc1>>CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncsc6c5)CC4)n3n2)cc1)C(C)(C)C -US20100234351A1,1,CC(C)(CO)S(=O)(=O)CCN.O=CC1=Cc2c(ncnc2Nc2ccc(Oc3cccc(C(F)(F)F)c3)c(Cl)c2)NCC1>>CC(C)(CO)S(=O)(=O)CCNCC1=Cc2c(ncnc2Nc2ccc(Oc3cccc(C(F)(F)F)c3)c(Cl)c2)NCC1 -US07851473B2,2,Cn1ncc(Br)c1NC(=O)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>Cn1ncc(Br)c1NC(=O)N1CCN(c2nc(-c3ccccc3)ns2)CC1 -US20040180926A1,3,Fc1ccc(CCl)cc1.O=C1CCN(Cc2ccccc2)CC1>>OC1(Cc2ccc(F)cc2)CCN(Cc2ccccc2)CC1 -US20130252936A1,2,CC(=O)OC(C)=O.CCOC(=O)Cn1nc(-c2ccc(F)cc2)cc1N>>CCOC(=O)Cn1nc(-c2ccc(F)cc2)cc1NC(C)=O -US20090054431A1,9,CC(C)(C)OC(=O)NC1Cc2ccc(Br)cc2C1.[C-]#N>>CC(C)(C)OC(=O)NC1Cc2ccc(C#N)cc2C1 -US20050113397A1,6,Cc1c(-c2ccccc2)c(N2CC(N(C)C(=O)OC(C)(C)C)C2)n2c(nc3ncccc32)c1C#N>>CNC1CN(c2c(-c3ccccc3)c(C)c(C#N)c3nc4ncccc4n23)C1 -US06147097,2,CC(=O)Cl.CC(C)c1nc(COCCO)n(C)c1Sc1cc(Cl)cc(Cl)c1>>CC(=O)OCCOCc1nc(C(C)C)c(Sc2cc(Cl)cc(Cl)c2)n1C -US05294609,6,COC(=O)C(C)(C)COC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(COC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O -US20100125064A1,1,N#CCBr.c1ccc(N2CCNCC2)nc1>>N#CCN1CCN(c2ccccn2)CC1 -US20100216991A1,1,C[O-].Nc1nc(Cl)nc2nc[nH]c12>>COc1nc(N)c2[nH]cnc2n1 -US20090270350A1,1,COc1ccc(Cn2c(C)cc(O)cc2=O)c(OC)c1.N#Cc1ccccc1CBr>>COc1ccc(Cn2c(C)cc(OCc3ccccc3C#N)cc2=O)c(OC)c1 -US05641789,7,COc1ccc(NS(=O)(=O)C(F)(F)F)cc1CC1C(=O)c2cc(OCc3nc4cc(F)c(F)cc4s3)ccc2OC1(C)C>>COc1ccc(NS(=O)(=O)C(F)(F)F)cc1C[C@H]1[C@@H](O)c2cc(OCc3nc4cc(F)c(F)cc4s3)ccc2OC1(C)C -US07238714B2,1,COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)cnc2Cl)cc1.Cc1ccc(O)c(C)c1>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)cnc2Oc2ccc(C)cc2C)cc1 -US20110313151A1,2,N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1.O=C(O)C[C@@H]1COCCO1>>O=C(C[C@@H]1COCCO1)N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1 -US05169860,2,NS(=O)(=O)c1cc2ccccc2o1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)NS(=O)(=O)c1cc2ccccc2o1 -US04159331,7,CCCOc1ccc(N2CCN(S(=O)(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1>>CCCOc1ccc(N2CCN(S(=O)(=O)c3ccc(N)cc3)CC2)cc1 -US04677129,7,C#CCN1C(=O)C2CC(c3ccc([N+](=O)[O-])cc3)(C2)C1=O>>C#CCN1C(=O)C2CC(c3ccc(N)cc3)(C2)C1=O -US20040138301A1,3,Cc1cc(C=O)cc(C)c1O.N#CCC#N>>Cc1cc(C=C(C#N)C#N)cc(C)c1O -US04138289,3,CC(C)CC[P+](C)(C)C.C[C@H](C=O)CCCl>>CC(C)C/C=C\[C@@H](C)CCCl -US20050085517A1,9,Cc1nc(N)ccc1Br.N#C[Cu]>>Cc1nc(N)ccc1C#N -US20150210688A1,3,COC(=O)c1ccc(Br)cc1.[Mg+]C1CC1>>COC(=O)c1ccc(C2CC2)cc1 -US08022206B2,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Nc1ncc2ccoc2c1OCc1nnc2ccc(Cl)nn12>>Cn1cc(-c2ccc3nnc(COc4c(N)ncc5ccoc45)n3n2)cn1 -US20090062268A1,1,CCOC(=O)C1CCCNC1.ClCCBr>>CCOC(=O)C1CCCN(CCCl)C1 -US20130085164A1,3,CC[Mg+].O=Cc1ccc(Br)cn1>>CCC(O)c1ccc(Br)cn1 -US20110195934A1,1,COc1cc(NC(=O)c2nn(-c3ccc(Cl)cc3)cc2CCl)ccc1O>>COc1cc(N2Cc3cn(-c4ccc(Cl)cc4)nc3C2=O)ccc1O -US20100227880A1,1,CN1CCNCC1.O=Cc1c(CN2C(=O)c3ccccc3C2=O)nc2ccccn12>>CN1CCN(Cc2c(CN3C(=O)c4ccccc4C3=O)nc3ccccn23)CC1 -US20050119320A1,6,CCOC(=O)CCNC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)N(C)C)cc2)s1>>Cc1nc(NC(=O)NCCC(=O)O)sc1-c1ccc(S(=O)(=O)N(C)C)cc1 -US20150252057A1,6,CC(C)(CO)CCCN1CC2CN(C(=O)OC(C)(C)C)CCN2C1=O>>CC(C)(CO)CCCN1CC2CNCCN2C1=O -US20060058295A1,3,Brc1ccc2nccnc2c1.OB(O)c1c(-c2ccccn2)nn2c1CCC2>>c1ccc(-c2nn3c(c2-c2ccc4nccnc4c2)CCC3)nc1 -US04791097,2,CCCCCCCCCCCC(O)CCCCCCCC.O=C(O)c1ccccc1>>CCCCCCCCCCCC(CCCCCCCC)OC(=O)c1ccccc1 -US20120208827A1,7,O=C(C1CC1)N1CC[C@@H](CNc2cc(C(F)(F)F)ccc2[N+](=O)[O-])C1>>Nc1ccc(C(F)(F)F)cc1NC[C@@H]1CCN(C(=O)C2CC2)C1 -US20120108583A1,2,Cc1nc2c(o1)c(C(=O)O)cc1nc(Nc3c(Cl)cccc3Cl)[nH]c12.Nc1ccc(Br)cc1>>Cc1nc2c(o1)c(C(=O)Nc1ccc(Br)cc1)cc1nc(Nc3c(Cl)cccc3Cl)[nH]c12 -US05308854,1,CCc1cc(O)c(OC)nc1C.ClCc1nc2ccccc2o1>>CCc1cc(OCc2nc3ccccc3o2)c(OC)nc1C -US20130190290A1,2,COc1ccc(N)cc1-n1ccn2nc(-c3cccnc3)cc12.O=C(O)c1cccc(S(F)(F)(F)(F)F)c1>>COc1ccc(NC(=O)c2cccc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 -US20100080770A1,2,C=CCC(C)(C)CCOC(=O)N[C@H](C(=O)O)C(C)(C)C.C=Cc1cc2cc([C@@]3(OC)CN[C@H](C(=O)OC)C3)ccc2cc1OC>>C=CCC(C)(C)CCOC(=O)N[C@H](C(=O)N1C[C@](OC)(c2ccc3cc(OC)c(C=C)cc3c2)C[C@H]1C(=O)OC)C(C)(C)C -US04093812,8,O=[N+]([O-])c1ccc(-c2nn(-c3ccccc3)cc2CO)o1>>O=Cc1cn(-c2ccccc2)nc1-c1ccc([N+](=O)[O-])o1 -US20060094776A1,1,OCCCCCl.Oc1c(Cl)cc(OCc2ccccc2)cc1Cl>>OCCCCOc1c(Cl)cc(OCc2ccccc2)cc1Cl -US20050176775A1,2,CN.Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1cc(C(=O)O)ccc1F>>CNC(=O)c1ccc(F)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)c1 -US20090227603A1,3,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(S(=O)(=O)C(C)C)c2)c1CCC(=O)OCC.OB(O)c1ccc(Cl)cc1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc(Cl)cc3)cc(S(=O)(=O)C(C)C)c2)c1CCC(=O)OCC -US20090270443A1,7,Cc1nc(N(Cc2ccccc2)Cc2ccccc2)c([N+](=O)[O-])c(NNC(=O)OC(C)(C)C)c1C>>Cc1nc(N(Cc2ccccc2)Cc2ccccc2)c(N)c(NNC(=O)OC(C)(C)C)c1C -US20100305092A1,1,O=Cc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1.OCC1CNCCO1>>OCC1CN(Cc2ccc(-c3noc(-c4nnn(-c5ccccc5F)c4-c4ccncc4)n3)cc2)CCO1 -US04239901,9,CC(C(=O)Cl)c1ccc(-n2cc(Cl)cn2)c(Cl)c1.N>>CC(C(N)=O)c1ccc(-n2cc(Cl)cn2)c(Cl)c1 -US20130291227A1,2,CC(C)(C)OC(=O)N(CCO)c1cn(-c2cccnc2)nc1Cl.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N(CCOS(C)(=O)=O)c1cn(-c2cccnc2)nc1Cl -US20080194826A1,1,COC(=O)c1cc(OCCC2(CC=O)CCCCC2)cc(C(=O)OC)c1.Cc1ccc(NC2CCNCC2)cc1>>COC(=O)c1cc(OCCC2(CCN3CCC(Nc4ccc(C)cc4)CC3)CCCCC2)cc(C(=O)OC)c1 -US20050038060A1,2,C=CC(=O)Cl.O=C(OCc1ccccc1)N1CCC2(CC1)CNc1ccccc12>>C=CC(=O)N1CC2(CCN(C(=O)OCc3ccccc3)CC2)c2ccccc21 -US20090149514A1,9,Cc1cc(C)cc(C=O)c1.NO>>Cc1cc(C)cc(C=NO)c1 -US20130184248A1,1,CC[O-].Clc1cc(I)ccn1>>CCOc1ccnc(Cl)c1 -US06063782,1,Cc1c(C)n(CC2CC2C)c2c(Cl)nncc12.OCc1ccc(F)cc1F>>Cc1c(C)n(CC2CC2C)c2c(OCc3ccc(F)cc3F)nncc12 -US20030045540A1,6,COC(=O)c1cc2c(Br)csc2cn1>>O=C(O)c1cc2c(Br)csc2cn1 -US05124332,6,CCOC(=O)CC1CCC2(CC1)OCCO2>>O=C(O)CC1CCC2(CC1)OCCO2 -US07858781B2,2,COc1ccc2c(COc3cccc4[nH]c(C(=O)O)cc34)coc2c1.C[C@H]1CN([C@@H](C)CN2CCC(N)CC2)CC[C@@H]1O>>COc1ccc2c(COc3cccc4[nH]c(C(=O)NC5CCN(C[C@H](C)N6CC[C@H](O)[C@@H](C)C6)CC5)cc34)coc2c1 -US20080167348A1,7,CS(=O)(=O)c1cc(-c2ccncc2)ccc1N>>CS(=O)(=O)c1cc(C2CCNCC2)ccc1N -US07906502B2,1,CC(C)(C)OC(=O)COc1ccc(C=O)cc1.Cc1ccc(N)cc1>>Cc1ccc(/N=C/c2ccc(OCC(=O)OC(C)(C)C)cc2)cc1 -US20120010182A1,2,COc1ccc(CNc2nncs2)c(OC)c1.N#Cc1cc(S(=O)(=O)Cl)ccc1F>>COc1ccc(CN(c2nncs2)S(=O)(=O)c2ccc(F)c(C#N)c2)c(OC)c1 -US20110245210A1,6,COc1ccc(N2C(=O)c3ccccc3C2=O)c(OC)n1>>COc1ccc(N2C(=O)c3ccccc3C2=O)c(O)n1 -US05565485,1,CCOC(=O)C(Br)c1ccc2c(c1)OCO2.COC(=O)c1ccc(O)c(CC(C)C)c1>>CCOC(=O)C(Oc1ccc(C(=O)OC)cc1CC(C)C)c1ccc2c(c1)OCO2 -US05654297,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1Cl.c1cc2c(s1)CCCCN2>>O=C(c1ccc([N+](=O)[O-])cc1Cl)N1CCCCc2sccc21 -US04618610,1,CC(=O)Nc1cc(C(=O)C(C)=NO)ccc1Cl.NNC(N)=S>>CC(=O)Nc1cc(C(=NNC(N)=S)C(C)=NO)ccc1Cl -US20040106653A1,1,C[C@H](Cc1ccc(S(=O)(=O)c2ccc(F)cc2C=O)cc1)NC(=O)C(F)(F)F.Oc1ccccc1>>C[C@H](Cc1ccc(S(=O)(=O)c2ccc(Oc3ccccc3)cc2C=O)cc1)NC(=O)C(F)(F)F -US20140171414A1,1,CNC.COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2n[nH]c(=O)n2C1c1ccc(C#N)cc1CBr>>COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2n[nH]c(=O)n2C1c1ccc(C#N)cc1CN(C)C -US08846684B2,2,O=C(C1CCNCC1)N1CCCCC1.O=C(O)c1cc2ccccc2n1Cc1ccc(F)cc1>>O=C(c1cc2ccccc2n1Cc1ccc(F)cc1)N1CCC(C(=O)N2CCCCC2)CC1 -US04187305,1,Clc1nc(NC2CC2)nc(NC2CC2)n1.NC1CC1>>C1CC1Nc1nc(NC2CC2)nc(NC2CC2)n1 -US06737409B2,2,CS[C@H]([C@@H](C)C(=O)O)[C@@H]1CCCN1C(=O)OC(C)(C)C.NCCc1cccc(O)c1>>CS[C@H]([C@@H](C)C(=O)NCCc1cccc(O)c1)[C@@H]1CCCN1C(=O)OC(C)(C)C -US07550485B2,2,NC1CCCCC1.O=C(O)C(c1cccc(Cl)c1)C1(O)CCCCC1>>O=C(NC1CCCCC1)C(c1cccc(Cl)c1)C1(O)CCCCC1 -US20110294118A1,2,CC1=[N+](CCCCCC(=O)O)c2ccc(Br)cc2C1(C)C.CCO>>CCOC(=O)CCCCC[N+]1=C(C)C(C)(C)c2cc(Br)ccc21 -US05610144,2,CC(C)(C)OC(=O)[C@@H]1CS[C@H](c2ccccc2)N1C(=O)CN.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CC(C)(C)OC(=O)[C@@H]1CS[C@H](c2ccccc2)N1C(=O)CNC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 -US08609848B2,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OC.O=S(=O)(Cl)c1ccccc1Cl>>COc1ccc(C2=NN(C3CCN(S(=O)(=O)c4ccccc4Cl)CC3)C(=O)C2(C)C)cc1OC -US20060270706A1,9,OC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1>>c1ccc(C(c2ccccc2)(c2ccccc2)N2CCCCC2)cc1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nccs4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nccs4)cc2)CCN3CC(C)C)cc1 -US20090042880A1,3,CCNc1nccc(C(C)=O)n1.CCOC(=O)C(=O)C(=O)OCC>>CCNc1nccc(C(=O)CC(O)(C(=O)OCC)C(=O)OCC)n1 -US07919506B2,1,C[S-].Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2C(Br)C2CCCCC2)n1>>CSC(c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1)C1CCCCC1 -US06054448,6,COC(=O)C1CC(CC#N)C1>>N#CCC1CC(C(=O)O)C1 -US05279764,1,CCCCC[C@@H]1CC[C@@H](C(=O)O)CC1.CCCCCc1ccc(-c2ccc(O)c(F)c2F)cc1>>CCCCCc1ccc(-c2ccc(OC(=O)[C@@H]3CC[C@@H](CCCCC)CC3)c(F)c2F)cc1 -US20070249670A1,6,CCOC[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)OC>>CCOC[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)O -US07393868B2,1,N#CCBr.Oc1ccc(Br)cc1>>N#CCOc1ccc(Br)cc1 -US20150252038A1,2,NS(=O)(=O)C1CC1.O=C(O)c1cc(C2CC2)c(OCC2CCN(S(=O)(=O)c3cc(Cl)c(Br)cc3F)CC2)cc1F>>O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(OCC2CCN(S(=O)(=O)c3cc(Cl)c(Br)cc3F)CC2)cc1F -US20090318477A1,9,CC(C)OC(=O)N1CCC(Oc2cccc3c2CCN3c2ccc(I)cc2)CC1.N#C[Cu]>>CC(C)OC(=O)N1CCC(Oc2cccc3c2CCN3c2ccc(C#N)cc2)CC1 -US20070123504A1,2,CCN(CC)c1ccc(N)cn1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>CCN(CC)c1ccc(NC(=O)c2nc(-c3ccccc3)oc2C(F)(F)F)cn1 -US20120077812A1,1,NC(=O)CBr.OB(O)c1ccc(S)cc1>>NC(=O)CSc1ccc(B(O)O)cc1 -US20050239781A1,2,CN(C)CCN1CC(C(=O)O)CC1=O.Nc1cc(Cl)cc2c1[nH]c1cnccc12>>CN(C)CCN1CC(C(=O)Nc2cc(Cl)cc3c2[nH]c2cnccc23)CC1=O -US20150175563A1,6,CCOC(=O)c1sc(-c2ccncc2)cc1Cc1ccc2ccccc2c1>>O=C(O)c1sc(-c2ccncc2)cc1Cc1ccc2ccccc2c1 -US08466169B2,2,CCOC(=O)c1cc(OCC)cc(S(F)(F)(F)(F)F)c1.CNOC>>CCOc1cc(C(=O)N(C)OC)cc(S(F)(F)(F)(F)F)c1 -US20100280268A1,1,CCCCCC=O.COC(=O)c1cc(Oc2ccc(N)cc2)ccc1N>>CCCCCCNc1ccc(Oc2ccc(N)c(C(=O)OC)c2)cc1 -US20030064912A1,2,CC(C)(C)OC(=O)CCC(CP(=O)(CN)OC(C)(C)C)C(=O)OC(C)(C)C.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)CCC(CP(=O)(CNC(=O)c1ccccc1)OC(C)(C)C)C(=O)OC(C)(C)C -US08143270B2,9,CNc1nc2c(Cl)nc3ccccc3c2n1C.N>>CNc1nc2c(N)nc3ccccc3c2n1C -US07812022B2,3,C#Cc1ccc(OC)c(NC(=O)C(F)(F)F)c1.Clc1ccnc(Cl)n1>>COc1ccc(C#Cc2ccnc(Cl)n2)cc1NC(=O)C(F)(F)F -US20030216571A1,7,O=C1c2ccccc2COc2ccc(C=Cc3ccc4cc(F)c(F)cc4n3)cc21>>OC1c2ccccc2COc2ccc(/C=C/c3ccc4cc(F)c(F)cc4n3)cc21 -US20080004273A1,1,O=C(NCCCl)Nc1cccc(F)c1>>O=C1NCCN1c1cccc(F)c1 -US05332675,6,CC(=O)OC(C)c1ccc(-c2ccc(C(=O)OCc3ccccc3)cc2)cc1>>CC(O)c1ccc(-c2ccc(C(=O)OCc3ccccc3)cc2)cc1 -US20120059019A1,2,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)ccc3C)c(F)c12.NC1(c2nc3cnccc3o2)CC1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5nc6cnccc6o5)CC4)ccc3C)c(F)c12 -US06982348B2,7,CCOC(=O)C(Cc1ccc(C(F)(F)F)cc1)C(=O)c1ccc(F)c(F)c1>>CCOC(=O)C(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)c(F)c1 -US05053409,1,C1CNCCN1.Cc1ccc(F)c(S(=O)(=O)O)c1>>Cc1ccc(N2CCNCC2)c(S(=O)(=O)O)c1 -US20080056987A1,1,CC(=O)NCCN.CCOC(=O)c1cnc2ccc3c(c2c1Cl)CCS3(=O)=O>>CCOC(=O)c1cnc2ccc3c(c2c1NCCNC(C)=O)CCS3(=O)=O -US04004026,9,N.O=C(O)C1CCc2cc(C3CCCCCC3)c(Cl)cc21>>NC(=O)C1CCc2cc(C3CCCCCC3)c(Cl)cc21 -US08183262B2,3,CC(C)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-n2cnc(Br)c2)n1.CC1(C)OB(c2cnc(N)nc2)OC1(C)C>>CC(C)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-n2cnc(-c3cnc(N)nc3)c2)n1 -US07348324B2,3,CC(C)C(=O)Cl.O=C(N1CCC(Cc2ccccc2)CC1)C(F)(F)F>>CC(C)C(=O)c1ccc(CC2CCN(C(=O)C(F)(F)F)CC2)cc1 -US20050148602A1,6,CCOC(=O)[C@]1(Cc2ccc(Br)cc2)CCCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC[C@@]1(Cc1ccc(Br)cc1)C(=O)O -US20130231499A1,8,CCCCC/C=C\CCCC(O)CCCCCCCCCC>>CCCCC/C=C\CCCC(=O)CCCCCCCCCC -US08501746B2,2,Cc1nc(-n2ccc(OCc3ccccc3)cc2=O)sc1C(=O)O.NCc1nccs1>>Cc1nc(-n2ccc(OCc3ccccc3)cc2=O)sc1C(=O)NCc1nccs1 -US04188486,4,CCc1ccc(C(=O)O)nc1.Nc1ccccc1N>>CCc1ccc(-c2nc3ccccc3[nH]2)nc1 -US20050136444A1,1,N=C(N)NN.O=Cc1cccc(F)c1>>N=C(N)NN=Cc1cccc(F)c1 -US20090062251A1,1,N#Cc1ccc(F)c(Cl)c1.NCCF>>N#Cc1ccc(NCCF)c(Cl)c1 -US05071999,6,CCOC(=O)N1CC2CC(C)N(Cc3ccccc3)C2C1>>CCOC(=O)N1CC2CC(C)NC2C1 -US20090239810A1,2,Clc1cccc(OC2CCNCC2)n1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>O=C(NCC(=O)N1CCC(Oc2cccc(Cl)n2)CC1)c1cc(-c2ccccc2)[nH]n1 -US20090247577A1,1,CC(C)(C)OC(=O)N1CC(C=O)C(Cc2cc(F)cc(F)c2)C1.NCc1ccncc1>>CC(C)(C)OC(=O)N1CC(CNCc2ccncc2)C(Cc2cc(F)cc(F)c2)C1 -US20120251551A1,3,CC1(C)OB(c2cccs2)OC1(C)C.N#Cc1ccc(Cl)nc1>>N#Cc1ccc(-c2cccs2)nc1 -US04258120,7,CC(=O)Cc1ccccc1>>CC(O)Cc1ccccc1 -US07659279B2,1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cc(OCc2ccccc2)cc2ncnc(Cl)c12.Nc1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cc(OCc2ccccc2)cc2ncnc(Nc3ccc(F)c(Cl)c3)c12 -US05026856,1,Clc1cccc2c1CNC2.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)c(F)c2c1=O>>O=C(O)c1cn(C2CC2)c2c(F)c(N3Cc4cccc(Cl)c4C3)c(F)c(F)c2c1=O -US05206235,2,CC(C)(CC(=O)O)NC(=O)OC(C)(C)C.N[C@@H]1CSc2ccccc2NC1=O>>CC(C)(CC(=O)N[C@@H]1CSc2ccccc2NC1=O)NC(=O)OC(C)(C)C -US20080004253A1,1,CC(C)S.O=[N+]([O-])c1ccc(F)cc1>>CC(C)Sc1ccc([N+](=O)[O-])cc1 -US04806145,1,Cn1c(C(F)F)nn(-c2cc(O)c(Cl)cc2Cl)c1=O.NC(=O)CI>>Cn1c(C(F)F)nn(-c2cc(OCC(N)=O)c(Cl)cc2Cl)c1=O -US20130029948A1,1,CCOC(=O)Cn1cc(Sc2c(C)[nH]c3c(F)c(Cl)ccc23)cn1.CCn1cc(Br)cn1>>CCOC(=O)Cn1cc(Sc2c(C)n(-c3cnn(CC)c3)c3c(F)c(Cl)ccc23)cn1 -US20100075965A1,3,CC(=O)Nc1cn2cc(-c3cnc(N)c(Cl)c3)ccc2n1.OB(O)c1ccc(C(F)(F)F)cc1>>CC(=O)Nc1cn2cc(-c3cnc(N)c(-c4ccc(C(F)(F)F)cc4)c3)ccc2n1 -US04654344,7,COc1cc(OC(C)=O)ccc1-c1nc2nccnc2[nH]1>>COc1cc(O)ccc1-c1nc2nccnc2[nH]1 -US05852038,2,CNC.COC(=O)c1ccnc(C(=O)O)c1>>COC(=O)c1ccnc(C(=O)N(C)C)c1 -US04082751,9,CC(C)COc1ccccc1-c1ncc(C(N)=O)c(=O)[nH]1>>CC(C)COc1ccccc1-c1ncc(C#N)c(=O)[nH]1 -US20070037787A1,2,CN(Cc1ccc(CC(=O)O)cc1)CC(O)C(O)C(O)C(O)CO.NCc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1>>CN(Cc1ccc(CC(=O)NCc2ccc(C3C(CCC(O)c4ccc(F)cc4)C(=O)N3c3ccc(F)cc3)cc2)cc1)CC(O)C(O)C(O)C(O)CO -US20140213448A1,1,CCN(C(=O)CCS)c1cn(-c2cccnc2)nc1Cl.CN(C(=O)CCl)c1cn(-c2cccnc2)nc1Cl>>CCN(C(=O)CCSCC(=O)N(C)c1cn(-c2cccnc2)nc1Cl)c1cn(-c2cccnc2)nc1Cl -US04772600,2,C1CSCN1.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>O=C(Cn1c(-c2ccc(Cl)cc2)nc2cccnc21)N1CCSC1 -US05994544,6,COC(=O)c1cc([N+](=O)[O-])ccc1-c1cc(C)ccc1OC>>COc1ccc(C)cc1-c1ccc([N+](=O)[O-])cc1C(=O)O -US08399465B2,1,C1CCNCC1.CS(=O)(=O)OCCc1c[nH]c2ccc(Oc3nc4ccccc4s3)cc12>>c1ccc2sc(Oc3ccc4[nH]cc(CCN5CCCCC5)c4c3)nc2c1 -US20050187266A1,7,Cc1oc(-c2ccccc2)nc1CCOc1ccc(C=O)cn1>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(CO)cn1 -US20100317657A1,3,COc1nc2cc(B3OC(C)(C)C(C)(C)O3)cnc2n1C.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>COc1nc2cc(-c3ccc4ncc5c(c4c3)n(-c3cn(C)nc3C)c(=O)n5C)cnc2n1C -US06727245B2,6,COC(=O)c1ccc(-c2cccc(-n3c(=O)c(Cc4ccccc4)nc4cccnc43)c2)cc1>>O=C(O)c1ccc(-c2cccc(-n3c(=O)c(Cc4ccccc4)nc4cccnc43)c2)cc1 -US20140371195A1,1,CC(C)(C)OC(=O)CN.CCOC(=O)c1ccnc(C=O)c1>>CCOC(=O)c1ccnc(CNCC(=O)OC(C)(C)C)c1 -US06703421B1,2,CC(C)(C)OC(=O)NC1Cc2ccc(C(=O)O)cc2C1.NCc1ccccc1>>CC(C)(C)OC(=O)NC1Cc2ccc(C(=O)NCc3ccccc3)cc2C1 -US20100197908A1,2,CC(=O)O.CNC1CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1 -US20030055064A1,9,COC(=O)C(C)(C)c1ccc(CN=[N+]=[N-])cc1>>COC(=O)C(C)(C)c1ccc(CN)cc1 -US20130196992A1,3,O=c1c(I)c(OCc2ccccc2)ccn1CC1CC1.OB(O)C1CC1>>O=c1c(C2CC2)c(OCc2ccccc2)ccn1CC1CC1 -US20110288111A1,1,COC(=O)[C@@H](N)Cc1c[nH]cn1.O=C1CCC2(CCCCC2)CC1>>COC(=O)C(Cc1c[nH]cn1)NC1CCC2(CCCCC2)CC1 -US20080269210A1,3,CS(=O)(=O)c1cccc(B(O)O)c1.Clc1nc(N2CCOCC2)c2cc(I)sc2n1>>CS(=O)(=O)c1cccc(-c2cc3c(N4CCOCC4)nc(Cl)nc3s2)c1 -US04085129,2,CCC(C)c1ccccc1O.O=C(Cl)Cl>>CCC(C)c1ccccc1OC(=O)Cl -US08455495B2,1,CN.COc1ccc(Cn2ncc(Br)c(Br)c2=O)cc1>>CNc1c(Br)cnn(Cc2ccc(OC)cc2)c1=O -US20080076806A1,2,Cc1cccc(C(N)c2ccccc2)c1.O=C(O)CNC(=O)c1ccc(F)cc1>>Cc1cccc(C(NC(=O)CNC(=O)c2ccc(F)cc2)c2ccccc2)c1 -US04443607,1,CC(O)CCl.O=c1[nH]cc(-c2ccccc2)c2ccccc12>>CC(O)Cn1cc(-c2ccccc2)c2ccccc2c1=O -US07094798B1,6,COc1ccc2[nH]c3c(-c4ccccc4)cc4c(c3c2c1)C(=O)NC4=O>>O=C1NC(=O)c2c1cc(-c1ccccc1)c1[nH]c3ccc(O)cc3c21 -US20030004181A1,6,CCOC(=O)CN(C(=O)c1ccc2sc(CNc3ccc(C(=N)N)cc3)nc2c1)c1ccccc1>>N=C(N)c1ccc(NCc2nc3cc(C(=O)N(CC(=O)O)c4ccccc4)ccc3s2)cc1 -US20100256097A1,2,C1COCCN1.O=C(O)COCc1cccc(Br)n1>>O=C(COCc1cccc(Br)n1)N1CCOCC1 -US20120101105A1,1,CC1(CO)CC1.Cc1ccc(O)cn1>>Cc1ccc(OCC2(C)CC2)cn1 -US20150038708A1,6,CN(CC(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1)C(=O)C(F)(F)F>>CNCC(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1 -US20110172216A1,3,CC1(C)OB(c2cnc3[nH]ccc3c2)OC1(C)C.COc1cccc(Nc2nc(Cl)nc3c2cnn3C)c1>>COc1cccc(Nc2nc(-c3cnc4[nH]ccc4c3)nc3c2cnn3C)c1 -US20060189650A1,1,CC(C)(C)OC(=O)N1CCC(CCS(=O)(=O)c2ccc(O)cc2)CC1.N#CCBr>>CC(C)(C)OC(=O)N1CCC(CCS(=O)(=O)c2ccc(OCC#N)cc2)CC1 -US06737409B2,2,CSC(C(C)C(=O)O)C1CCCN1C(=O)OC(C)(C)C.NCCc1ccccc1>>CSC(C(C)C(=O)NCCc1ccccc1)C1CCCN1C(=O)OC(C)(C)C -US08394858B2,2,O=C(O)[C@@H]1CC[C@@H](NS(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1.O=C1N[C@@H](c2ccccc2)CO1>>O=C1OC[C@H](c2ccccc2)N1C(=O)[C@@H]1CC[C@@H](NS(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1 -US06127354,6,CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc2ccccc2c1)C(=O)N1CCc2ccccc2C1>>CN[C@H](Cc1ccc2ccccc2c1)C(=O)N1CCc2ccccc2C1 -US20100105714A1,3,CCOC(=O)CP(=O)(OCC)OCC.Cc1cccc(C2=C(c3ccc4ncnn4c3)OC3(CCC(=O)CC3)C2=O)c1>>CCOC(=O)C=C1CCC2(CC1)OC(c1ccc3ncnn3c1)=C(c1cccc(C)c1)C2=O -US06320040B1,1,Cc1cn([C@@]2([SiH](c3ccccc3)c3ccccc3)C[C@H](O)[C@@H](COC(C)(C)C)O2)c(=O)[nH]c1=O.ClCOCc1ccccc1>>Cc1cn([C@@]2([SiH](c3ccccc3)c3ccccc3)C[C@H](O)[C@@H](COC(C)(C)C)O2)c(=O)n(COCc2ccccc2)c1=O -US20100249229A1,6,CCC(C)C1=C[C@H]2[C@@H](C1)C[C@@]2(CN)CC(=O)OC(C)(C)C>>CCC(C)C1=C[C@H]2[C@@H](C1)C[C@@]2(CN)CC(=O)O -US20090143440A1,2,Nc1ccc(Cl)cn1.O=C(O)c1cc(Cl)[nH]n1>>O=C(Nc1ccc(Cl)cn1)c1cc(Cl)[nH]n1 -US04487779,6,Cc1cc(OCc2ccccc2)cc(C)c1NC(=O)NC(=N)N>>Cc1cc(O)cc(C)c1NC(=O)NC(=N)N -US06071901,2,Clc1ccc2c(c1)Nc1ccccc1CC2.O=C(Cl)CCCl>>O=C(CCCl)N1c2ccccc2CCc2ccc(Cl)cc21 -US20120252792A1,2,Nc1ccc(Cl)cc1.O=C(Nc1ccccc1C(=O)O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(Nc1ccccc1C(=O)Nc1ccc(Cl)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20050192339A1,1,O=C1CC[C@@]2(c3ccc4c(c3)OCO4)CCN(Cc3ccccc3)[C@H]2C1.[NH4+]>>NC1CC[C@@]2(c3ccc4c(c3)OCO4)CCN(Cc3ccccc3)[C@H]2C1 -US20100075953A1,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1cc(OCCCN2CCCCC2)ccc1Br>>CC(C)(C)OC(=O)N1CCN(c2ccc(OCCCN3CCCCC3)cc2Cl)CC1 -US08809376B2,6,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Cc5cccc(OC)c5)ccc(F)c43)ccc21>>COc1cccc(Cc2ccc(F)c3c2CC[C@H]3Oc2ccc3c(c2)OC[C@H]3CC(=O)O)c1 -US20080255152A1,1,CCCCCN.NC(=O)c1ccc(Oc2ccc(C=O)cc2F)cn1>>CCCCCNCc1ccc(Oc2ccc(C(N)=O)nc2)c(F)c1 -US07008940B1,4,COC(=O)CSC.COc1ccc(N)c(C)c1C>>COc1cc2c(c(C)c1C)NC(=O)C2SC -US20140163012A1,1,CC(C)(C)OC(=O)N1CCc2oc3cc(Br)ccc3c2C1.O=C1CN(CCc2ccc(Cl)cn2)CCN1>>CC(C)(C)OC(=O)N1CCc2oc3cc(N4CCN(CCc5ccc(Cl)cn5)CC4=O)ccc3c2C1 -US07393868B2,1,CCI.CCOC(=O)c1ccc(O)c(I)c1>>CCOC(=O)c1ccc(OCC)c(I)c1 -US07732480B2,7,COC(=O)c1ccc(C#N)c(Cl)c1C>>Cc1c(CO)ccc(C#N)c1Cl -US20130129677A1,2,CCOC(=O)CCNc1cccc(C(F)(F)F)c1.O=C(Cl)CCl>>CCOC(=O)CCN(C(=O)CCl)c1cccc(C(F)(F)F)c1 -US20030099574A1,6,CCOC(=O)c1cnc2c(ccc3c(-c4ccccc4)ccnc32)c1O>>O=C(O)c1cnc2c(ccc3c(-c4ccccc4)ccnc32)c1O -US20060100234A1,6,COCc1cc(OCc2ccccc2)c2nc(C)c(C)n2c1>>COCc1cc(O)c2nc(C)c(C)n2c1 -US20110003820A1,2,CC1NCCn2c(-c3cccnc3)ccc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2ccc(-c3cccnc3)n2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US05216026,2,CCCCCS(N)(=O)=O.O=C=Nc1ccc(Cl)cc1>>CCCCCS(=O)(=O)NC(=O)Nc1ccc(Cl)cc1 -US20100075965A1,6,CC(C)(C)OC(=O)N1CC(Oc2nc(Br)cnc2N)C1>>Nc1ncc(Br)nc1OC1CNC1 -US20140100250A1,1,Cc1cc(Br)nc(Br)c1.Nc1cc(C2CC2)ccn1>>Cc1cc(Br)nc(Nc2cc(C3CC3)ccn2)c1 -US07091214B2,6,CCOCc1nc2c(N)nc3cc(-c4ccccc4)ccc3c2n1CC1CCN(C(=O)OC(C)(C)C)CC1>>CCOCc1nc2c(N)nc3cc(-c4ccccc4)ccc3c2n1CC1CCNCC1 -US05686470,1,CNC.CS(=O)(=O)c1ccc(-c2cc(C#N)c(Cl)nc2-c2ccc(F)cc2)cc1>>CN(C)c1nc(-c2ccc(F)cc2)c(-c2ccc(S(C)(=O)=O)cc2)cc1C#N -US20110269738A1,3,CC(C)Oc1ccc(-c2ncc(Br)s2)cc1C(F)(F)F.CCc1c(C=O)cccc1B1OC(C)(C)C(C)(C)O1>>CCc1c(C=O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)s1 -US20100144751A1,1,CC1(NC(=O)OCc2ccccc2)CCNCC1.COCCOc1ccn2c(-c3ccc4cccc(OS(=O)(=O)C(F)(F)F)c4n3)cnc2c1>>COCCOc1ccn2c(-c3ccc4cccc(N5CCC(C)(NC(=O)OCc6ccccc6)CC5)c4n3)cnc2c1 -US20110015119A1,7,CNC(=O)COCCOc1ccc([N+](=O)[O-])cc1>>CNCCOCCOc1ccc([N+](=O)[O-])cc1 -US20070155740A1,1,CC[C@H](COC)n1cc(Cl)nc(Cl)c1=O.COc1cc(Cl)c2c(c1)CCN2>>CC[C@H](COC)n1cc(Cl)nc(N2CCc3cc(OC)cc(Cl)c32)c1=O -US20040077669A1,3,Clc1cc(Cl)ncn1.OB(O)c1c(F)cccc1F>>Fc1cccc(F)c1-c1cc(Cl)ncn1 -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)Cc4cccnc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](Cc4cccnc4)NC(=O)c4c[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US20090082434A1,9,[N-]=[N+]=NCC1Cc2cccc(-c3ccccc3)c2O1>>NCC1Cc2cccc(-c3ccccc3)c2O1 -US06825222B2,6,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccc(-c4cncnc4)cc3)oc2C)cc1>>Cc1oc(-c2ccc(-c3cncnc3)cc2)nc1CCOc1ccc(OC(C)(C)C(=O)O)cc1 -US08569512B2,1,COC(=O)c1ccc2cc[nH]c2c1.Cc1ccc(Br)cc1>>COC(=O)c1ccc2ccn(-c3ccc(C)cc3)c2c1 -US03931247,7,CC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)o1>>CC(O)c1ccc(-c2ccc([N+](=O)[O-])cc2)o1 -US09133168B2,1,C[O-].Clc1cc(Cl)nc(Cl)n1>>COc1cc(Cl)nc(Cl)n1 -US06965048B2,2,CN(C[C@@H]1CC[C@@H](C(=O)O)CC1)C(=O)Oc1ccc(Cl)cc1.CNCCCO>>CN(C[C@@H]1CC[C@@H](C(=O)N(C)CCCO)CC1)C(=O)Oc1ccc(Cl)cc1 -US20060069110A1,1,CN(c1ccnc(F)n1)c1ccnc(-c2ccccc2)n1.NCCc1ccccc1Cl>>CN(c1ccnc(NCCc2ccccc2Cl)n1)c1ccnc(-c2ccccc2)n1 -US08153644B2,1,CCOC(=O)C(C)(C)C1CCNCC1.O=[N+]([O-])c1ccc(Cl)nc1>>CCOC(=O)C(C)(C)C1CCN(c2ccc([N+](=O)[O-])cn2)CC1 -US05231101,2,CCOC(=O)CN1CCC(=C2c3ccc(C#N)cc3CCc3cccnc32)CC1.NCCN>>N#Cc1ccc2c(c1)CCc1cccnc1C2=C1CCN(CC(=O)NCCN)CC1 -US06239131B1,6,CC(C)(C)OC(=O)NC1CN(C2CCCCC2)c2ccccc2N(CC(=O)C2CCCCC2)C1=O>>NC1CN(C2CCCCC2)c2ccccc2N(CC(=O)C2CCCCC2)C1=O -US20150105393A1,1,COC(=O)c1ccc(O)c(C)c1.OCC(F)F>>COC(=O)c1ccc(OCC(F)F)c(C)c1 -US20130190330A1,6,COC(=O)c1ccc(-c2ccccc2Cl)s1>>O=C(O)c1ccc(-c2ccccc2Cl)s1 -US04478749,6,COP(=O)([O-])N1CC(NC(=O)OCc2ccccc2)C1=O>>COP(=O)([O-])N1C[C@H](N)C1=O -US07544703B2,2,CC(=O)Nc1cc(CO)ccn1.CS(=O)(=O)Cl>>CC(=O)Nc1cc(COS(C)(=O)=O)ccn1 -US04681898,1,CCc1noc(C)c1C(=O)Nc1cccc(F)c1.CN(C)CCCl>>CCc1noc(C)c1C(=O)N(CCN(C)C)c1cccc(F)c1 -US20130324547A1,2,CC(C)(C)OC(=O)N1CCNCC1.COc1ccc(C2CC(C(F)(F)F)n3nc(-c4cccc(C(=O)O)c4)cc3N2)cc1OC>>COc1ccc(C2CC(C(F)(F)F)n3nc(-c4cccc(C(=O)N5CCN(C(=O)OC(C)(C)C)CC5)c4)cc3N2)cc1OC -US07579351B2,8,OCc1cc2cc(OCc3ccccc3)cnc2[nH]1>>O=Cc1cc2cc(OCc3ccccc3)cnc2[nH]1 -US20150274711A1,2,CCOC(=O)[C@@H]1C[C@H](N)CN1CC1CCCC1.O=C(O)c1ccc2ccccc2c1O>>CCOC(=O)[C@@H]1C[C@H](NC(=O)c2ccc3ccccc3c2O)CN1CC1CCCC1 -US20150218143A1,3,CCOC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2Br)cc1.OB(O)C1CC1>>CCOC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C2CC2)cc1 -US20120232283A1,1,BrCc1ccc(-c2ccccc2-c2nnnn2Cc2ccccc2)cc1.COC(=O)c1cccc([N+](=O)[O-])c1NC(=O)OC(C)(C)C>>COC(=O)c1cccc([N+](=O)[O-])c1N(Cc1ccc(-c2ccccc2-c2nnnn2Cc2ccccc2)cc1)C(=O)OC(C)(C)C -US20040157909A1,3,CCOC(=O)c1c(C)[nH]c(C=O)c1CCCN1CCN(C)CC1.O=C1Cc2c(cccc2-c2ccc(Cl)cc2)N1>>CCOC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3cccc(-c4ccc(Cl)cc4)c32)c1CCCN1CCN(C)CC1 -US20130324531A1,2,COCCOCCOCCO.COc1cc(C(=O)OCC(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F>>COCCOCCOCCOC(=O)COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1 -US07790756B2,2,CCOC(=O)Cl.Oc1ccc(F)cc1F>>CCOC(=O)Oc1ccc(F)cc1F -US04742171,6,COC(=O)C1CCC(=O)N1Cc1cccc(Cl)c1>>O=C(O)C1CCC(=O)N1Cc1cccc(Cl)c1 -US20100273806A1,6,CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(OC(F)(F)F)cc(N5CCCC5)c4)n3)cc21>>O=C(O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(OC(F)(F)F)cc(N5CCCC5)c4)n3)cc21 -US05641777,1,CO.NC(=O)NC1(c2ccccc2)CCN(CCC2(c3ccc(F)c(F)c3)CN(C(=O)c3ccccc3)CCO2)CC1>>CNC(=O)NC1(c2ccccc2)CCN(CCC2(c3ccc(F)c(F)c3)CN(C(=O)c3ccccc3)CCO2)CC1 -US20040044057A1,7,COc1ccc2c(c1)C(c1cccc(Cl)c1)=CCC2>>COc1ccc2c(c1)C(c1cccc(Cl)c1)CCC2 -US20130030012A1,1,CN1CCCn2c1cc(Cl)nc2=O.N#Cc1cc(F)cc(CO)c1>>CN1CCCn2c1cc(OCc1cc(F)cc(C#N)c1)nc2=O -US05156763,1,CCCCBr.Oc1cc(F)cc(F)c1>>CCCCOc1cc(F)cc(F)c1 -US07563822B2,5,CC(C)c1ccc(CCN)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)c1ccc(CCNC(=O)C(F)(F)F)cc1 -US20130035310A1,1,CC(C)(C)OC(=O)NC1CCNCC1.O=S(=O)(Nc1ncns1)c1ccc(Br)cc1>>CC(C)(C)OC(=O)NC1CCN(c2ccc(S(=O)(=O)Nc3ncns3)cc2)CC1 -USRE039198E1,1,CS(=O)(=O)OCC1COc2ccccc2O1.Fc1ccc2c(C3CCNCC3)noc2c1>>Fc1ccc2c(C3CCN(CC4COc5ccccc5O4)CC3)noc2c1 -US08148408B2,2,CC(C)(C)OC(=O)N1C[C@H]2CN(c3cncc(C(=O)O)c3)C[C@H]2C1.COc1cc(N)cc(OC)c1>>COc1cc(NC(=O)c2cncc(N3C[C@@H]4CN(C(=O)OC(C)(C)C)C[C@@H]4C3)c2)cc(OC)c1 -US20150266857A1,1,C1CNCCN1.O=S(=O)(c1ccccc1)n1cc(-c2ccc3oc(CCl)nc3c2)c2ccc(F)cc21>>O=S(=O)(c1ccccc1)n1cc(-c2ccc3oc(CN4CCNCC4)nc3c2)c2ccc(F)cc21 -US05538986,9,C=CCC1(CC=O)c2ccccc2CCc2ccccc21.NO>>C=CCC1(CC=NO)c2ccccc2CCc2ccccc21 -US20130040951A9,1,COc1cc(C=O)ccc1O.N#Cc1ccc(F)c2ccccc12>>COc1cc(C=O)ccc1Oc1ccc(C#N)c2ccccc12 -US09090596B2,7,COC(=O)CNCC(=O)c1cccc([N+](=O)[O-])c1O>>COC(=O)CNCC(=O)c1cccc(N)c1O -US05620991,3,CCOC(=O)C(=O)c1ccc(OC(C)=O)cc1.N#Cc1ccc2oc(C[P+](c3ccccc3)(c3ccccc3)c3ccccc3)cc2c1>>CCOC(=O)C(=Cc1cc2cc(C#N)ccc2o1)c1ccc(OC(C)=O)cc1 -US07217723B2,2,CNC[C@H](O)c1ccc(F)cc1.O=C1CCCc2c(S(=O)(=O)Cl)csc21>>CN(C[C@H](O)c1ccc(F)cc1)S(=O)(=O)c1csc2c1CCCC2=O -US05658922,1,CC[C@](C)(O)[C@H]1CC[C@H]2[C@@H]3[C@@H](C)C[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@@]21C.CI>>CC[C@](C)(O)[C@H]1CC[C@H]2[C@@H]3[C@@H](C)C[C@H]4N(C)C(=O)C=C[C@]4(C)[C@H]3CC[C@@]21C -US20060167052A1,2,CN=C=O.FC(F)(F)c1cc(CO[C@H]2CCNC[C@H]2c2ccccc2)cc(C(F)(F)F)c1>>CNC(=O)N1CC[C@H](OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](c2ccccc2)C1 -US07368451B2,6,CC(C)(C)OC(=O)NCCCCc1ccc(OCC#N)cc1>>N#CCOc1ccc(CCCCN)cc1 -US07977345B2,7,O=[N+]([O-])c1ccc(Oc2ncnc3[nH]ccc23)c(F)c1>>Nc1ccc(Oc2ncnc3[nH]ccc23)c(F)c1 -US20120309739A1,1,COCCBr.CSc1nc2oc(Br)c(-c3ccccc3)c2c(=O)[nH]1>>COCCn1c(SC)nc2oc(Br)c(-c3ccccc3)c2c1=O -US08518972B2,7,COC(=O)c1ccc(CN2CCOCC2)c(Cl)c1>>OCc1ccc(CN2CCOCC2)c(Cl)c1 -US20060183745A1,2,CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4N)ncn3)cccc2s1.CC(C)(C)OC(=O)N1[C@H](C(=O)O)CC[C@@H]1c1ccccc1>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)[C@@H]4CC[C@H](c5ccccc5)N4C(=O)OC(C)(C)C)ncn3)cccc2s1 -US07868205B2,4,CC(=O)CC(C)=O.NNc1ccc(C(=O)O)cc1>>Cc1cc(C)n(-c2ccc(C(=O)O)cc2)n1 -US05273975,7,COc1cccc(C)c1[N+](=O)[O-]>>COc1cccc(C)c1N -US20130116445A1,7,CCCC(=O)[C@@H](C[N+](=O)[O-])c1ccccc1>>CCC[C@@H](O)[C@@H](C[N+](=O)[O-])c1ccccc1 -US20050070582A1,1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc(C(=O)O)ccc2F)CC1.Cc1cc(C)cc(O)c1>>Cc1cc(C)cc(Oc2ccc(C(=O)O)cc2S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c1 -US20020107252A1,2,C[Si](C)(C)N=C=S.NC(=O)c1cc(-c2ccccc2)sc1N>>NC(=O)c1cc(-c2ccccc2)sc1NC(N)=S -US20120238540A1,1,CC(C)(C)OC(=O)NCCOCCOS(C)(=O)=O.COc1ccc([N+](=O)[O-])cc1O>>COc1ccc([N+](=O)[O-])cc1OCCOCCNC(=O)OC(C)(C)C -US20100226917A1,6,C[C@H]1[C@H](N(C)C(=O)OC(C)(C)C)CCCN1C(=O)OCc1ccccc1>>CN[C@@H]1CCCN(C(=O)OCc2ccccc2)[C@H]1C -US08609647B2,6,COC(=O)C1(CCCNCc2ccccc2)CCCN1C(=O)OC(C)(C)C>>COC(=O)C1(CCCNCc2ccccc2)CCCN1 -US07557213B2,1,BrCc1cccc(Br)n1.COc1ccc(C(=O)c2c[nH]c3ccc(C)nc3c2=O)cc1F>>COc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccc(C)nc3c2=O)cc1F -US06110967,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CN>>CNC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C -US20080004321A1,2,CCCc1c(OCc2cccc(N)c2)ccc(C(C)=O)c1O.N#Cc1cccc(S(=O)(=O)Cl)c1>>CCCc1c(OCc2cccc(NS(=O)(=O)c3cccc(C#N)c3)c2)ccc(C(C)=O)c1O -US08546392B2,2,CN.COc1cc(C(=O)O)cc(-c2ccc3cc(OC)ccc3c2)c1>>CNC(=O)c1cc(OC)cc(-c2ccc3cc(OC)ccc3c2)c1 -US20050148627A1,1,CCOC(=O)C1=Cc2cc(O)cc(OC)c2OC1C(F)(F)F.CI>>CCOC(=O)C1=Cc2cc(OC)cc(OC)c2OC1C(F)(F)F -US05210290,2,COC(=O)CS(=O)(=O)Cl.Nc1ccc(F)cc1C(F)(F)F>>COC(=O)CS(=O)(=O)Nc1ccc(F)cc1C(F)(F)F -US20120083482A1,3,CN(C)C=O.Clc1ccnc2ccsc12>>O=Cc1cc2nccc(Cl)c2s1 -US08541448B2,6,CCOP(=O)(CNCc1ccccc1)OCC>>CCOP(=O)(CN)OCC -US08629168B2,3,COCCN1CCN(c2ccc(Nc3nc4cccc(Br)c4o3)cc2C)CC1.Cc1cc(B2OC(C)(C)C(C)(C)O2)ccc1C(=O)N1CCOCC1>>COCCN1CCN(c2ccc(Nc3nc4cccc(-c5ccc(C(=O)N6CCOCC6)c(C)c5)c4o3)cc2C)CC1 -US05798402,1,CCCCCCCCCCCCCCCCCCBr.O=C(O)CCS>>CCCCCCCCCCCCCCCCCCSCCC(=O)O -US20090062322A1,6,Clc1ccc2c(c1)C1(CCN(Cc3ccccc3)CC1)OC2>>Clc1ccc2c(c1)C1(CCNCC1)OC2 -US08497281B2,7,O=C1CCC2=C(Cc3ccccc32)N1>>O=C1CC[C@@H]2c3ccccc3C[C@@H]2N1 -US06211242B1,6,CC(=O)OCCOc1ccccc1N(C)C(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C)cc2)cc1>>Cc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N(C)c3ccccc3OCCO)cc2)cc1 -US06545009B1,4,COC(=O)c1ccc(C(N)=S)cc1.O=C(CBr)c1ccc(C(F)(F)F)cc1>>COC(=O)c1ccc(-c2nc(-c3ccc(C(F)(F)F)cc3)cs2)cc1 -US07074794B2,6,CCOC(=O)c1ccc2oc(C3CCN([C@H]4C[C@@H](C(=O)N5CCSC5)N(C(=O)OC(C)(C)C)C4)CC3)nc2c1>>CC(C)(C)OC(=O)N1C[C@@H](N2CCC(c3nc4cc(C(=O)O)ccc4o3)CC2)C[C@H]1C(=O)N1CCSC1 -US09018382B2,3,CC1(C)OB(c2ccc(N3CCNCC3)nc2)OC1(C)C.Cc1cc(C)c(CNC(=O)c2cc(Br)cc3c2cnn3C(C)C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCNCC4)nc3)cc3c2cnn3C(C)C)c(=O)[nH]1 -US04931083,1,CCOC(=O)C(C)Br.Oc1ncn(-c2cccc(Br)c2)n1>>CCOC(=O)C(C)Oc1ncn(-c2cccc(Br)c2)n1 -US06346527B1,2,CCOC(=O)C1=Cc2cccc(N)c2OCC1.CN(C)S(=O)(=O)Cl>>CCOC(=O)C1=Cc2cccc(NS(=O)(=O)N(C)C)c2OCC1 -US04021479,9,O=C(O)CCC(O)c1ccc(-c2ccc(F)cc2)cc1>>O=C(O)CCCc1ccc(-c2ccc(F)cc2)cc1 -US20090181942A1,6,CCOC(=O)CC1CCN(C(=O)CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c(C(N)=O)ccc32)CC1>>COc1cccc([C@H]2O[C@H](CCC(=O)N3CCC(CC(=O)O)CC3)c3ccc(C(N)=O)n3-c3ccc(Cl)cc32)c1OC -US20090318493A1,3,CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(Br)ccc21.CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)C1>>CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(C(=O)C3CCN(C(=O)OC(C)(C)C)C3)ccc21 -US20010034352A1,7,CC(C)(C)OC(=O)NC1CCN(CC(=O)c2coc3ccccc23)CC1>>CC(C)(C)OC(=O)NC1CCN(CC(O)c2coc3ccccc23)CC1 -US20130296327A1,6,CN(C)C(=O)C(Cc1ccc(-c2cccc(F)c2F)nc1)NC(=O)OC(C)(C)C>>CN(C)C(=O)C(N)Cc1ccc(-c2cccc(F)c2F)nc1 -US20090082329A1,6,CC(=O)Nc1cc(CN2C(=O)N(c3ccc(S(=O)(=O)C(F)(F)F)cc3)C(=O)C2(C)C)ccn1>>CC1(C)C(=O)N(c2ccc(S(=O)(=O)C(F)(F)F)cc2)C(=O)N1Cc1ccnc(N)c1 -US20150057298A1,1,COC(=O)c1ccc(C=O)cc1F.COc1cccc(CN)c1>>COC(=O)c1ccc(CNCc2cccc(OC)c2)cc1F -US05789402,1,ClCCOc1cccc2[nH]ccc12.c1ccc2cc(C3CCNCC3)ccc2c1>>c1ccc2cc(C3CCN(CCOc4cccc5[nH]ccc45)CC3)ccc2c1 -US20040092507A1,2,CC(C)(C)OC(=O)N1CCN(c2ccccc2N)CC1.CC(C)N=C=O>>CC(C)NC(=O)Nc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1 -US20110076230A1,1,CN.Fc1ccc2[nH]c(-c3ccc(F)nc3)cc2c1>>CNc1ccc(-c2cc3cc(F)ccc3[nH]2)cn1 -US04291168,6,COc1cc2c(c(Cl)c1Cl)C(=O)C(c1ccccc1)C2>>O=C1c2c(cc(O)c(Cl)c2Cl)CC1c1ccccc1 -US20030078251A1,2,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc(C(=O)O)o3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc(C(=O)O)o3)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC -US20100105604A1,1,CCCO.O=C(O)c1cccc(CCl)c1>>CCCOCc1cccc(C(=O)O)c1 -US05290929,6,Cc1nc2cc(OCc3ccccc3)c(OCc3ccccc3)cc2nc1C(=O)OCc1ccccc1>>Cc1nc2cc(OCc3ccccc3)c(OCc3ccccc3)cc2nc1C(=O)O -US04868132,1,CN.COC(=O)Cc1ccc(CC(C)=O)cc1>>CNC(C)Cc1ccc(CC(=O)OC)cc1 -US20140323475A1,1,CC(=O)CCl.Oc1ccc(Cl)cc1C1OCCO1>>CC(=O)COc1ccc(Cl)cc1C1OCCO1 -US20090198057A1,6,CCOC(=O)c1cnc(-c2ccc(F)c(F)c2)nc1NCCc1ccccn1>>O=C(O)c1cnc(-c2ccc(F)c(F)c2)nc1NCCc1ccccn1 -US20090186879A1,8,CCC(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1c(C)nc(OC)nc1C>>CCC(=O)c1ccc(Cl)c2nc3n(c12)CCCN3c1c(C)nc(OC)nc1C -US20040242594A1,2,CCCCCCCCCCCCC(=O)O.COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1>>CCCCCCCCCCCCC(=O)OC1(C(CN(C)C)c2ccc(OC)cc2)CCCCC1 -US08691810B2,6,Cc1ccc(S(=O)(=O)n2c(-c3cnn(C4CCN(C(=O)OC(C)(C)C)CC4)c3)cc3c(-c4cnc(C5(O)CCC5)s4)c(Cl)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2c(-c3cnn(C4CCNCC4)c3)cc3c(-c4cnc(C5(O)CCC5)s4)c(Cl)cnc32)cc1 -US04337256,2,CCOC(=O)Cc1cccc2c(C(C)C)nccc12.CN>>CNC(=O)Cc1cccc2c(C(C)C)nccc12 -US20100093817A1,6,CCOC(=O)Cc1c[nH]c(=S)n1[C@H]1COc2c(F)cc(F)cc2C1>>O=C(O)Cc1c[nH]c(=S)n1[C@H]1COc2c(F)cc(F)cc2C1 -US07435744B2,2,CC(=O)OC(C)=O.Nc1ccc(NC(=O)CN2CCC(Cc3ccc(F)cc3)CC2)cc1>>CC(=O)Nc1ccc(NC(=O)CN2CCC(Cc3ccc(F)cc3)CC2)cc1 -US08580146B2,9,BrC(Br)(Br)Br.CCCc1ccc(CCCO)cc1>>CCCc1ccc(CCCBr)cc1 -US07888352B2,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.Cc1c(CN2CCN(C(=O)OC(C)(C)C)CC2)sc2c(N3CCOCC3)nc(Cl)nc12>>Cc1c(CN2CCN(C(=O)OC(C)(C)C)CC2)sc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc12 -US06030991,2,Cc1noc(N)c1Br.O=S(=O)(Cl)c1cc(Cl)ccc1Cl>>Cc1noc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1Br -US07220859B2,9,CC(C)(C)OC(=O)N[C@H]1C[C@@H](CBr)OC1=O.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@H]1C[C@@H](CN=[N+]=[N-])OC1=O -US20070249670A1,2,COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)c(F)c2)cc1N)[C@@H](C)OC(C)(C)C.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)c(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)[C@@H](C)OC(C)(C)C -US03975524,1,C1CNCCN1.Clc1cc2ccccc2c(N2CCOCC2)n1>>c1ccc2c(N3CCOCC3)nc(N3CCNCC3)cc2c1 -US20100063066A1,7,CC(C)(C)OC(=O)n1ncc2ccc([N+](=O)[O-])cc21>>CC(C)(C)OC(=O)n1ncc2ccc(N)cc21 -US04221910,9,CC(O)Cn1cnc2c(Cl)ncnc21.N>>CC(O)Cn1cnc2c(N)ncnc21 -US20100278833A1,9,COC(=O)c1sc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)cc1O[C@@H](C)c1ccccc1C(F)(F)F.N>>C[C@H](Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F -US20050282863A1,1,CCCCNC.ClCCCCCn1c2c(c3ccccc31)CCSc1ccccc1-2>>CCCCN(C)CCCCCn1c2c(c3ccccc31)CCSc1ccccc1-2 -US07135475B2,2,CNc1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1.Cc1cncc(C(=O)O)c1>>Cc1cncc(C(=O)N(C)c2ccc(Cc3nc4c([nH]3)c(=O)n(Cc3ccccc3F)c(=O)n4CC3CC3)cc2)c1 -US05591752,7,CC(=O)Oc1ccc2c(c1)C(=O)c1ccc(C#N)cc1CO2>>N#Cc1ccc2c(c1)COc1ccc(O)cc1C2=O -US04857530,1,C#CCNc1ccc(C(C)=O)cc1.CC(C)(C)C(=O)OCn1cnc2ccc(CBr)cc2c1=O>>C#CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(C)=O)cc1 -US05686586,3,C[SiH](C)Oc1c(C=O)ccc(C(C)(C)C)c1C12CC3CC(CC(C3)C1)C2.c1ccc([P+](CCC2OCCCO2)(c2ccccc2)c2ccccc2)cc1>>C[SiH](C)Oc1c(C=CCC2OCCCO2)ccc(C(C)(C)C)c1C12CC3CC(CC(C3)C1)C2 -US20120190666A1,7,CC(C)CCn1ccc([N+](=O)[O-])n1>>CC(C)CCn1ccc(N)n1 -US20140206663A1,7,C=C(C)c1cc2c(cc1OC1CN(C(=O)OC(C)(C)C)C1)N1C(=NNC(=O)C1C)CO2>>CC(C)c1cc2c(cc1OC1CN(C(=O)OC(C)(C)C)C1)N1C(=NNC(=O)C1C)CO2 -US20110224186A1,1,CC(C)(C)OC(=O)NCCSCc1cnccc1Cl.Cc1sc(N)nc1/C(=N/OC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(S)CCC12>>Cc1sc(N)nc1/C(=N/OC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(Sc3ccncc3CSCCNC(=O)OC(C)(C)C)CCC12 -US04977146,1,CCCBr.CSc1cc(C=O)cc(OCc2ccccc2)c1O>>CCCOc1c(OCc2ccccc2)cc(C=O)cc1SC -US08093385B2,7,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(-c3ccc4c(c3)OCO4)cc([N+](=O)[O-])c2)c1CCC(=O)OCC>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(N)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)OCC -US08759366B2,6,COC(=O)c1ccc(C(C)(O)c2ncc(-c3cc(C)cc(Nc4nccc(C(F)(F)F)n4)c3)s2)cn1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C(C)(O)c3ccc(C(=O)O)nc3)s2)c1 -US20100261708A1,1,Cc1ccc2nc(Cl)sc2c1.O=C(C1CCOCC1)N1CCCNCC1>>Cc1ccc2nc(N3CCCN(C(=O)C4CCOCC4)CC3)sc2c1 -US20040157741A1,2,N=C(N)c1ccc(F)c(Cl)c1.O=S(=O)(Cl)c1ccc(F)c(Cl)c1>>N=C(NS(=O)(=O)c1ccc(F)c(Cl)c1)c1ccc(F)c(Cl)c1 -US20050222175A1,1,COC(=O)c1cccc(CBr)c1.Clc1cc2c(NC3CCNCC3)ncnc2s1>>COC(=O)c1cccc(CN2CCC(Nc3ncnc4sc(Cl)cc34)CC2)c1 -US09073894B2,4,C#CCN.[N-]=[N+]=Nc1ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc1>>NCc1cn(-c2ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc2)nn1 -US07601714B2,1,Fc1ccccn1.N[C@@H]1CC[C@@H](CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+](=O)[O-])CC1>>O=[N+]([O-])c1cnc(NCc2ccccc2OC(F)(F)F)nc1NC[C@@H]1CC[C@@H](Nc2ccccn2)CC1 -US20080090860A1,1,CC(C)(C)c1cc(Br)c(O)c(C(C)(C)C)c1.CCCI>>CCCOc1c(Br)cc(C(C)(C)C)cc1C(C)(C)C -US20100087427A1,6,CC(C)c1cccc(C[C@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(Cc2ccccc2)c2ccc(Cl)cc2)c1>>CC(C)c1cccc(C[C@H]2CNC[C@@H]2CN(Cc2ccccc2)c2ccc(Cl)cc2)c1 -US08044056B2,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CNCC(=O)OC>>COC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C -US05004745,1,CN1CCNCC1.Cn1cc(C(=O)O)c(=O)c2cc3cc(F)c(Cl)cc3nc21>>CN1CCN(c2cc3nc4c(cc3cc2F)c(=O)c(C(=O)O)cn4C)CC1 -US07576082B2,6,COC(=O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cc1>>O=C(O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cc1 -US20140243336A1,1,CC(C)(C)OC(=O)Nc1cccc(COS(C)(=O)=O)n1.CN1CCNCC1>>CN1CCN(Cc2cccc(NC(=O)OC(C)(C)C)n2)CC1 -US20110034467A1,7,O=C(Nc1cncc2c1C(=O)N(Cc1cccc(I)c1)C2=O)c1ccc(Cl)s1>>O=C(Nc1cncc2c1CN(Cc1cccc(I)c1)C2=O)c1ccc(Cl)s1 -US20150111734A1,2,CC(=O)OC(C)C(=O)Cl.CCNc1cn(-c2cccnc2)nc1Cl>>CCN(C(=O)C(C)OC(C)=O)c1cn(-c2cccnc2)nc1Cl -US06946491B2,6,CC(C)(C)OC(=O)CCC(=O)c1c(F)cccc1F>>O=C(O)CCC(=O)c1c(F)cccc1F -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1oc2cc(Br)ccc2c1NC(=O)Nc1c(Cl)cccc1Cl)C1CCCCC1>>O=C(Nc1c(Cl)cccc1Cl)Nc1c(C(=O)N[C@H](C(=O)O)C2CCCCC2)oc2cc(Br)ccc12 -US20040058990A1,1,NNC(=S)Nc1cccc2ccccc12.O=Cc1ccc(O)cc1O>>Oc1ccc(C=NNC(=S)Nc2cccc3ccccc23)c(O)c1 -US07332510B2,1,Cc1nc(C#Cc2ccnc(Cl)c2)c[nH]1.FC(F)(F)c1ccnc(Cl)n1>>Cc1nc(C#Cc2ccnc(Cl)c2)cn1-c1nccc(C(F)(F)F)n1 -US05591762,4,CCCc1nc2c(Cl)cc(N3Cc4ccccc4C3=O)cc2n1Cc1ccc(-c2ccccc2C#N)cc1.[N-]=[N+]=[N-]>>CCCc1nc2c(Cl)cc(N3Cc4ccccc4C3=O)cc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US06340679B1,6,Cc1ccc(S(=O)(=O)N[C@@H](Cc2ccc(OCCCC(=O)NC3=NCCCN3)cc2)C(=O)OC(C)(C)C)cc1>>Cc1ccc(S(=O)(=O)N[C@@H](Cc2ccc(OCCCC(=O)NC3=NCCCN3)cc2)C(=O)O)cc1 -US07045528B2,6,COC(=O)c1c(C)sc2cc(Oc3ccnc4cc(C(=O)N5CC[C@@H](OC)C5)sc34)ccc12>>CO[C@@H]1CCN(C(=O)c2cc3nccc(Oc4ccc5c(C(=O)O)c(C)sc5c4)c3s2)C1 -US04871746,7,CCOC(=O)CC[C@H](NC(=O)c1ccc(CN(Cc2cnc3nc(NC(=O)C(C)(C)C)nc(O)c3c2)C(=O)C(F)(F)F)cc1)C(=O)OCC>>CCOC(=O)CC[C@H](NC(=O)c1ccc(CN(CC2CNc3nc(NC(=O)C(C)(C)C)nc(O)c3C2)C(=O)C(F)(F)F)cc1)C(=O)OCC -US20140315881A1,2,Cc1cc(Cl)ccc1C(N)c1ccccc1.Cc1ncccc1-c1ccc2cc(CC(=O)O)ccc2n1>>Cc1cc(Cl)ccc1C(NC(=O)Cc1ccc2nc(-c3cccnc3C)ccc2c1)c1ccccc1 -US03960836,2,CC(=O)OC(C)=O.NC(=O)c1[nH]nc([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O>>CC(=O)n1nc([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(O)c1C(N)=O -US07196104B2,6,CCOC(=O)c1csc(-c2cccc(OC)c2)n1>>COc1cccc(-c2nc(C(=O)O)cs2)c1 -USRE041315E1,6,CCCN1CCN(c2ccc(OC)c(S(C)(=O)=O)c2)CC1>>CCCN1CCN(c2ccc(O)c(S(C)(=O)=O)c2)CC1 -US20130040930A1,6,COc1ccc(CN2CC(C(C)C)N(c3ccc(C(=O)N4CCN(c5ncc(C)cc5C)CC4)cc3)C2=O)cc1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)NCC4C(C)C)cc3)CC2)c(C)c1 -US06153786,3,C#CCCCC.CCCCOC(=O)Cl>>CCCCC#CC(=O)OCCCC -US20150111734A1,2,Clc1nn(-c2cccnc2)cc1NCC1CC1.O=C(O)CN1CCCC1=O>>O=C1CCCN1CC(=O)N(CC1CC1)c1cn(-c2cccnc2)nc1Cl -US05643920,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCc2c(-c3ccc(Cl)cc3)cn3cccc1c23>>C=C1CCc2c(-c3ccc(Cl)cc3)cn3cccc1c23 -US20100048549A1,7,Cc1ccc(S(=O)(=O)N[C@@H](COCc2ccccc2)C(=O)NCCN(C)C)c2ccccc12>>Cc1ccc(S(=O)(=O)N[C@@H](CNCCN(C)C)COCc2ccccc2)c2ccccc12 -US20150203515A1,6,CC[C@@H]1CC[C@H](Oc2ccc3nc(NC4C5CCCC4CC(C(=O)OC)C5)ccc3c2C(F)(F)F)CC1>>CC[C@@H]1CC[C@H](Oc2ccc3nc(NC4C5CCCC4CC(C(=O)O)C5)ccc3c2C(F)(F)F)CC1 -US20110243844A1,2,Nc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1.O=C(Cl)c1ccccn1>>O=C(Nc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1)c1ccccn1 -US08916560B2,6,COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCC[C@@H]3C(F)(F)F)nc2c1>>O=C(O)c1ccc2nc(-c3ccccc3)c(N3CCC[C@@H]3C(F)(F)F)nc2c1 -US08513250B2,1,C#Cc1cnc2c(NCCCO)nc3cc(C(F)(F)F)ccc3n12.C1=COCCC1>>C#Cc1cnc2c(NCCCOC3CCCCO3)nc3cc(C(F)(F)F)ccc3n12 -US05189036,2,CCCCN.O=C(O)C1CCN(C(=O)c2ccc(F)cc2)CC1>>CCCCNC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 -US05574044,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Cc1ccc2c(c1)[nH]c(=O)n2C1CCNCC1>>Cc1ccc2c(c1)[nH]c(=O)n2C1CCN(C2CCN(C(=O)OC(C)(C)C)CC2)CC1 -US20090253696A1,3,Fc1ccc(-c2ccc3nc(Cl)nc(Cl)c3n2)cc1.[Mg+]CCC1OCCCO1>>Fc1ccc(-c2ccc3nc(Cl)nc(CCC4OCCCO4)c3n2)cc1 -US08772510B2,1,O=C(O)CCCl.c1ccc(-c2nc[nH]n2)cc1>>O=C(O)CCn1cnc(-c2ccccc2)n1 -US05905149,1,CCOC(=O)C(C)Br.O=C1Nc2ccccc2C1=Cc1ccc(O)c2ncccc12>>CCOC(=O)C(C)Oc1ccc(C=C2C(=O)Nc3ccccc32)c2cccnc12 -US20090023753A1,2,COC(C)(C)C(=O)Cl.Nc1cc(CCl)ccn1>>COC(C)(C)C(=O)Nc1cc(CCl)ccn1 -US20120226037A1,1,Cc1cc(C2CC2)cc(C)c1O.Clc1nc(Cl)c2[nH]ccc2n1>>Cc1cc(C2CC2)cc(C)c1Oc1nc(Cl)nc2cc[nH]c12 -US04977144,1,BrCCC1CCCCC1.CCOC(=O)Nc1cc(Cl)c2nc[nH]c2n1>>CCOC(=O)N(CCC1CCCCC1)c1cc(Cl)c2nc[nH]c2n1 -US20060004084A1,3,O=C1Cc2ccccc2N1.O=C1OCc2cc(CC3OCCO3)ccc21>>O=C1Nc2ccccc2C1=C1OCc2cc(CC3OCCO3)ccc21 -US07763639B2,7,Fc1c(OC(F)(F)F)cccc1C1=CCNCC1>>Fc1c(OC(F)(F)F)cccc1C1CCNCC1 -US04315016,1,C=CCOC(Cl)CCCC.c1nc[nH]n1>>C=CCOC(CCCC)n1cncn1 -US20020151712A1,3,Brc1cncc(OCC2CCN(Cc3ccccc3)C2)c1.C[Mg+]>>Cc1cncc(OCC2CCN(Cc3ccccc3)C2)c1 -US05496816,8,Cc1ccc2sc(Cl)nc2n1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc2sc(Cl)[n+]([O-])c2n1 -US20030195209A1,2,Cc1nc(N)c2ncn(CCCCN)c2c1C.O=C(Cl)N1CCOCC1>>Cc1nc(N)c2ncn(CCCCNC(=O)N3CCOCC3)c2c1C -US20120245136A1,2,C1=C(c2ccccc2)c2ccccc2OC12CCNCC2.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)N2CCC3(C=C(c4ccccc4)c4ccccc4O3)CC2)cc1OC -US20020193367A1,2,Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)on1.Cc1cc(N)c(NC(=O)OC(C)(C)C)cc1N(C)CC(C)C>>Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C)c(N(C)CC(C)C)cc3NC(=O)OC(C)(C)C)c2)on1 -US04683242,1,CCI.Nc1c(CC(=O)O)cccc1C(=O)c1ccc(Br)cc1>>CCOC(=O)Cc1cccc(C(=O)c2ccc(Br)cc2)c1N -US20070142371A1,2,COc1c(N)cc(C(C)(C)C)cc1NS(C)(=O)=O.O=C(O)c1ccc(F)c(-n2cc(-c3cccnc3)nn2)c1>>COc1c(NC(=O)c2ccc(F)c(-n3cc(-c4cccnc4)nn3)c2)cc(C(C)(C)C)cc1NS(C)(=O)=O -US05656627,7,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)c1nc2ccccc2o1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)OC(C)(C)C)C(O)c1nc2ccccc2o1 -US20100016319A1,1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2O)cc1OCc1ccccc1.Clc1ccnc(Cl)n1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)cc1OCc1ccccc1 -US20040072818A1,2,CNc1ccccc1.Nc1cc(N2CCN(C(=O)NCC(=O)O)CC2)c2ccc(Cl)cc2n1>>CN(C(=O)CNC(=O)N1CCN(c2cc(N)nc3cc(Cl)ccc23)CC1)c1ccccc1 -US07964591B2,1,CCCCCNC(=O)c1ccc(Cl)nn1.O=C(c1ccccc1C(F)(F)F)N1CCNCC1>>CCCCCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 -US04849420,2,COc1cc2c(cc1OC)C(Cc1ccccc1CC(=O)O)NCC2>>COc1cc2c(cc1OC)C1Cc3ccccc3CC(=O)N1CC2 -US20040014763A1,6,CCOC(=O)/C=C/C=C/C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(/C=C/C=C/C(=O)O)CC1 -US20150183768A1,7,CCOC(=O)C1OCCN1C(=O)c1cc(C)ccc1-n1nccn1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCOC2CO)c1 -US05998433,3,C=O.CCNCC.O=C(CCc1cccc(CCc2ccccc2)c1)N1CCc2ccoc2C1>>CCN(CC)Cc1cc2c(o1)CN(C(=O)CCc1cccc(CCc3ccccc3)c1)CC2 -US20060211678A1,2,CN1CCN(C(=O)Cl)CC1.Cn1ncc2cc(Nc3ncnc4[nH]c(C5=CCNCC5)cc34)ccc21>>CN1CCN(C(=O)N2CC=C(c3cc4c(Nc5ccc6c(cnn6C)c5)ncnc4[nH]3)CC2)CC1 -US20100311766A1,2,CCN=C=O.Nc1nc2cc(Br)nc(Br)c2s1>>CCNC(=O)Nc1nc2cc(Br)nc(Br)c2s1 -US08691854B2,1,NNC(N)=S.O=CC=Cc1cccc(O)c1>>NC(=S)NN=CC=Cc1cccc(O)c1 -US20080070864A1,2,CC(C)(C)c1ccc(C(=O)Cl)cc1.CNC(C)c1nc2ccccc2c(=O)n1-c1ccc(OC)cc1>>COc1ccc(-n2c(C(C)N(C)C(=O)c3ccc(C(C)(C)C)cc3)nc3ccccc3c2=O)cc1 -US20040259910A1,4,CCOC(=O)C(CNC(=O)Cc1cccc(OC(C)CC)c1)c1ccc(OC)c(OC)c1>>CCOC(=O)C1CN=C(Cc2cccc(OC(C)CC)c2)c2cc(OC)c(OC)cc21 -US08828996B2,2,CO.O=C(O)c1ccc(O)cn1>>COC(=O)c1ccc(O)cn1 -US05510531,8,CCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CO)CCCC>>CCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CCCC -US04348399,1,CCCCCCCCCCCCCCCCBr.COC(=O)C(=O)Cc1ccc(N)cc1>>CCCCCCCCCCCCCCCCNc1ccc(CC(=O)C(=O)OC)cc1 -US05574042,2,CC(=O)OC(C)=O.Cc1nc2c(OCc3c(Cl)ccc(N)c3Cl)cccn2c1Br>>CC(=O)Nc1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl -US20090075996A1,6,COC(=O)c1cc2c(cc1O)-c1[nH]c3c(F)c(C(F)(F)F)c(Br)cc3c1CC2>>O=C(O)c1cc2c(cc1O)-c1[nH]c3c(F)c(C(F)(F)F)c(Br)cc3c1CC2 -US04959361,3,C#C[Si](C)(C)C.Cc1nnc2n1-c1ccc(I)cc1C(c1ccccc1Cl)=NC2>>Cc1nnc2n1-c1ccc(C#C[Si](C)(C)C)cc1C(c1ccccc1Cl)=NC2 -US05942511,1,C=CCS.CCCCOc1ccc(Cl)nn1>>C=CCSc1ccc(OCCCC)nn1 -US20150284411A1,1,C=CCBr.CS(=O)(=O)c1nc2nc(I)c(Cl)cc2[nH]1>>C=CCn1c(S(C)(=O)=O)nc2nc(I)c(Cl)cc21 -US20100311748A1,1,CN(C)CCO.Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(OCc2cc(Cl)ccn2)cc1>>Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(OCc2cc(OCCN(C)C)ccn2)cc1 -US20090042896A1,1,CC(O)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1.Oc1ccc(C(F)(F)F)cn1>>CC(Oc1ccc(C(F)(F)F)cn1)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1 -US20070287725A1,9,CCOCc1nc2c(Cl)nc3ccccc3c2n1CC1CC(C)=NO1.N>>CCOCc1nc2c(N)nc3ccccc3c2n1CC1CC(C)=NO1 -US08802864B2,1,CCC(=O)Cl.CCC(=O)N1CC(Cc2n[nH]c(=O)n2-c2ccc(Br)cc2F)C1>>CCC(=O)N1CC(Cc2nn(C(=O)CC)c(=O)n2-c2ccc(Br)cc2F)C1 -US08318928B2,2,CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)O)cccc1OC(F)F.N#Cc1ccc(N)nc1>>CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)Nc2ccc(C#N)cn2)cccc1OC(F)F -US08288412B2,6,Cc1cc2c(cc1Br)[nH]c(=O)n2C1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc2c(cc1Br)[nH]c(=O)n2C1CCNCC1 -US20060142335A1,2,O=C=Nc1ccccc1Cl.Oc1ccc2c(c1)CCCN2Cc1ccccc1>>O=C(Nc1ccccc1Cl)Oc1ccc2c(c1)CCCN2Cc1ccccc1 -US04154947,1,N=C(NN)NCc1ccco1.O=Cc1c(Cl)cccc1Cl>>N=C(NCc1ccco1)NN=Cc1c(Cl)cccc1Cl -US07087635B2,1,CC(C)(Cc1c[nH]c2c(O)cccc12)NC(=O)OC(C)(C)C.N#Cc1cccnc1Cl>>CC(C)(Cc1c[nH]c2c(Oc3ncccc3C#N)cccc12)NC(=O)OC(C)(C)C -US20050164989A1,6,NP(N)(=O)N1CCCC[C@H](NC(=O)OCc2ccccc2)C1=O>>N[C@H]1CCCCN(P(N)(N)=O)C1=O -US20140121200A1,1,CC1(C)OB(c2ccc(Cl)nc2)OC1(C)C.CN>>CNc1ccc(B2OC(C)(C)C(C)(C)O2)cn1 -US04213998,6,CCOC(=O)c1cc2cc(-c3ccc(NC(C)=O)cc3)ccc2o1>>CCOC(=O)c1cc2cc(-c3ccc(N)cc3)ccc2o1 -US20040034071A1,1,C=C(C)C.CC(C)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(=O)O>>CC(C)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(=O)OC(C)(C)C -US20100256097A1,1,CC(C)(O)c1ccc(-c2cc(C(N)=O)c(Nc3cccc(CO)n3)s2)c(F)c1.Cc1nnc(CCl)o1>>Cc1nnc(COCc2cccc(Nc3sc(-c4ccc(C(C)(C)O)cc4F)cc3C(N)=O)n2)o1 -US20150025068A1,3,COC(=O)c1ccc(NS(=O)(=O)c2cnc(Cl)c(Br)c2)cc1O.COc1cccc(B(O)O)c1F>>COC(=O)c1ccc(NS(=O)(=O)c2cnc(Cl)c(-c3cccc(OC)c3F)c2)cc1O -US04560692,2,CO.O=C(O)c1ccncc1>>COC(=O)c1ccncc1 -US20080038785A1,2,COCCO.NC(CC(=O)O)c1ccccc1>>COCCOC(=O)CC(N)c1ccccc1 -USRE039679E1,1,Fc1ccc2c(CCCCl)n[nH]c2c1.c1cc2c3c(c1)[C@@H]1CNCC[C@@H]1N3CCO2>>Fc1ccc2c(CCCN3CC[C@H]4[C@@H](C3)c3cccc5c3N4CCO5)n[nH]c2c1 -US09120749B2,1,CN(C)[C@@H]1CC[C@@H](CN)CC1.O=C(c1cnc2ccc(Br)cc2c1Cl)C1CC1>>CN(C)[C@@H]1CC[C@@H](CNc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)CC1 -US20060189661A1,3,Fc1ccc(Br)nc1.N#Cc1cccc(-c2ccc(Br)o2)c1>>N#Cc1cccc(-c2ccc(-c3ccc(F)cn3)o2)c1 -US20080064703A1,3,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.Clc1ccc(OC2CN3CCC2CC3)nn1>>c1cc(-c2ccc(OC3CN4CCC3CC4)nn2)c2cc[nH]c2c1 -US20150126449A1,6,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(CC#N)cccc4nn23)CC1>>N#CCc1cccc2nn3c(C4CCNCC4)cc(=O)[nH]c3c12 -US08546359B2,6,COC(=O)CCC(C)(c1ccc2c(C(F)(F)F)c(O[C@@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1)[N+](=O)[O-]>>CC(CCC(=O)O)(c1ccc2c(C(F)(F)F)c(O[C@@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1)[N+](=O)[O-] -US20100331297A1,1,CC(C)(C)n1nc(O)c2c(N)ncnc21.Clc1nccc2ccccc12>>CC(C)(C)n1nc(Oc2nccc3ccccc23)c2c(N)ncnc21 -US06265434B1,6,O=C(OCc1ccccc1)[C@@H](CC1CCC1)N1C[C@H](c2cccc(F)c2)[C@@H](CN2CCC(CCCc3cc(F)cc(F)c3)CC2)C1>>O=C(O)[C@@H](CC1CCC1)N1C[C@H](c2cccc(F)c2)[C@@H](CN2CCC(CCCc3cc(F)cc(F)c3)CC2)C1 -US05795887,6,CC1=NC(NC(=O)Nc2cccc3cnn(C(=O)OC(C)(C)C)c23)C(=O)N(CC(=O)N(c2ccccc2)C(C)C)c2ccccc21>>CC1=NC(NC(=O)Nc2cccc3cn[nH]c23)C(=O)N(CC(=O)N(c2ccccc2)C(C)C)c2ccccc21 -US05980780,1,CCCCCCCCCBr.O=C(O)c1ccc(O)cc1>>CCCCCCCCCOc1ccc(C(=O)O)cc1 -US20130090323A1,3,Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1I.OB(O)c1ccc(OC(F)F)nc1>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1ccc(OC(F)F)nc1 -US20090143354A1,1,CC(C)(C)OC(=O)[C@H]1CCCN1.O=C(NCC1CCCCC1)c1c(Cl)ccc2nc(Cl)ccc12>>CC(C)(C)OC(=O)[C@H]1CCCN1c1ccc2c(C(=O)NCC3CCCCC3)c(Cl)ccc2n1 -US06040433,8,CC(C)(C)C(=O)OC[C@H]1O[C@@H](Sc2ccccc2)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)C(=O)OC[C@H]1O[C@@H](S(=O)c2ccccc2)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C -US20150274695A1,7,Cc1cc(C(=O)O)cc(Cl)n1>>Cc1cc(CO)cc(Cl)n1 -US20050107362A1,2,CC(C)(C)OC(=O)N[C@H]1c2ccccc2C[C@@H]1N.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>CC(C)(C)OC(=O)N[C@H]1c2ccccc2C[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1 -US06664214B1,7,COC(=O)C(C)Oc1cccc(C=O)c1>>COC(=O)C(C)Oc1cccc(CO)c1 -US08153814B2,2,Nc1ccncn1.O=S(=O)(Cl)c1cc(Cl)c(F)cc1F>>O=S(=O)(Nc1ccncn1)c1cc(Cl)c(F)cc1F -US04092356,6,CCCCCC(O)CCCC(CCCCCCC(=O)O)C(O)CCOC>>CCCCCC(O)CCCC(CCCCCCC(=O)O)C(O)CCO -US07135487B2,7,CC(C)c1ccc(C(C)C#N)cc1>>CC(C)c1ccc(C(C)CN)cc1 -US04622405,1,C=O.COc1ccc2c(c1OC)CC1CNCC21>>COc1ccc2c(c1OC)CC1CN(C)CC21 -US20070259851A1,7,CCOC(=O)C(C(OCC)OCC)[N+](=O)[O-]>>CCOC(=O)C(N)C(OCC)OCC -US07101868B2,1,NCc1ccc(F)cc1.O=C(Nc1ccc(C(F)(F)F)c(OCCN2CCCC2)c1)c1cccnc1Cl>>O=C(Nc1ccc(C(F)(F)F)c(OCCN2CCCC2)c1)c1cccnc1NCc1ccc(F)cc1 -US20090054467A1,1,CCCN1C(=O)NC2(CCN(Cc3cc4cnc(C#N)nc4n3CC(C)(C)C)CC2)C1=O.CI>>CCCN1C(=O)N(C)C2(CCN(Cc3cc4cnc(C#N)nc4n3CC(C)(C)C)CC2)C1=O -US20100280024A1,7,CC(C)(C)OC(=O)COC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(OCCO)CC1 -US20110015157A1,3,CC(=O)C[C@]1(c2ccccc2)CCN([C@@H](C)c2ccc(OC(F)F)cc2)C(=O)O1.C[Mg+]>>C[C@@H](c1ccc(OC(F)F)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O -US20100261710A1,6,CCOC(=O)c1cn2cc(-c3cccc(OC)c3)nc2s1>>COc1cccc(-c2cn3cc(C(=O)O)sc3n2)c1 -US20100272677A1,3,CCOP(=O)(Cc1ccc([N+](=O)[O-])cc1)OCC.COc1c(C=O)cc(Br)cc1C1(C)CC1>>COc1c(/C=C/c2ccc([N+](=O)[O-])cc2)cc(Br)cc1C1(C)CC1 -US04927822,1,CC(=O)SCCC(=O)Cl.CCOC(=O)C1NN=C(c2ccccc2)S1>>CCOC(=O)C1SC(c2ccccc2)=NN1C(=O)CCSC(C)=O -US20150236274A1,3,Brc1ccc(Oc2ccccc2)cc1Oc1ccccc1.OB(O)c1cccc2ccccc12>>c1ccc(Oc2ccc(-c3cccc4ccccc34)c(Oc3ccccc3)c2)cc1 -US20100160386A1,1,CCOC(=O)c1cnc(-c2ccc(F)cc2)cc1Cl.Oc1ccccc1Cl>>CCOC(=O)c1cnc(-c2ccc(F)cc2)cc1Oc1ccccc1Cl -US08987251B2,1,CC(C)(C)[Si](C)(C)Oc1c(Br)ccc2ccc(C=O)nc12.NNc1ccccn1>>CC(C)(C)[Si](C)(C)Oc1c(Br)ccc2ccc(C=NNc3ccccn3)nc12 -US08309581B2,1,COC(=O)c1ccc(CBr)cc1.Oc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2n1CC1CCCCC1>>COC(=O)c1ccc(COc2cc(Cl)ccc2-c2nc3cc(F)c(F)cc3n2CC2CCCCC2)cc1 -US04087428,2,NC1CCN(C2CCCCC2)C1.O=C(Cl)c1cc(Cl)nc2ccccc12>>O=C(NC1CCN(C2CCCCC2)C1)c1cc(Cl)nc2ccccc12 -US20100125064A1,7,N#Cc1ccc(Cl)cc1OCCN1CCCC1>>NCc1ccc(Cl)cc1OCCN1CCCC1 -US06919371B2,6,COC(=O)c1ccccc1-c1ccc2c(c1)CC[C@H](CNC[C@H](O)c1cccnc1)O2>>O=C(O)c1ccccc1-c1ccc2c(c1)CC[C@H](CNC[C@H](O)c1cccnc1)O2 -US20130274469A1,2,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.NCCF>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCCF)cn1 -US07625905B2,2,Cc1nn(-c2ccc(C(F)(F)F)cn2)c(C)c1C(=O)N1CC2CN(CCC3(c4ccccc4)CCNC3)CC2C1.O=C(Cl)C1CCCC1>>Cc1nn(-c2ccc(C(F)(F)F)cn2)c(C)c1C(=O)N1CC2CN(CCC3(c4ccccc4)CCN(C(=O)C4CCCC4)C3)CC2C1 -US07078414B2,6,CCOC(=O)c1cn(-c2ccnc3ccccc23)c(C)c1C>>Cc1c(C(=O)O)cn(-c2ccnc3ccccc23)c1C -US05329033,3,CCC(Cc1ccccc1C)C(=O)Cl>>CCC1Cc2c(C)cccc2C1=O -US06150528,9,ClCc1ccc(Cl)nc1>>Cc1ccc(Cl)nc1 -US04840971,1,BrCc1cccc(Oc2ccccc2)c1.OCC(c1ccc(Cl)cc1)C(F)(F)F>>FC(F)(F)C(COCc1cccc(Oc2ccccc2)c1)c1ccc(Cl)cc1 -US08455658B2,8,CC(O)c1nc(NC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1>>CC(=O)c1nc(NC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1 -US07659245B2,6,C=C[C@H]1C[C@@]1(NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C)C(=O)OCC>>C=C[C@H]1C[C@@]1(NC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)OCC -US20100009970A1,7,CC(C)C1=CCC(c2ccc(Cl)c(Cl)c2)c2ccccc21>>CC(C)C1CCC(c2ccc(Cl)c(Cl)c2)c2ccccc21 -US20130296312A1,1,CN1CCN(c2cccc(N)c2)CC1.Fc1ccc(-n2cc(-c3cccn4nc(Cl)nc34)cn2)cc1>>CN1CCN(c2cccc(Nc3nc4c(-c5cnn(-c6ccc(F)cc6)c5)cccn4n3)c2)CC1 -US08101607B2,6,CC(C)(C)OC(=O)N1CCN(Cc2cc3nc(-c4cccc5[nH]ccc45)nc(N4CCOCC4)c3s2)CC1>>c1cc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)c2cc[nH]c2c1 -US08501992B2,2,Fc1ccc(CNCc2ccccc2CNCc2ccc(F)cc2)cc1.O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1>>O=S(=O)(c1cc(Cl)cc(Cl)c1)N(Cc1ccc(F)cc1)Cc1ccccc1CNCc1ccc(F)cc1 -US20100286138A1,2,CC(C)(C)CC(=O)Cl.Cc1cc(Br)cc(C)c1N>>Cc1cc(Br)cc(C)c1NC(=O)CC(C)(C)C -US20050137243A1,2,COc1cc(CC(=O)O)ccc1OCc1ccccc1.Nc1ccc2cnn(CCN3CCCC3)c2c1>>COc1cc(CC(=O)Nc2ccc3cnn(CCN4CCCC4)c3c2)ccc1OCc1ccccc1 -US08436008B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1Cc2ccc(Br)cc2CN1>>CC1Cc2ccc(Br)cc2CN1C(=O)OC(C)(C)C -US08143251B2,1,COc1ccc(C2(c3nnc4ncc(-c5ccc(Br)cc5)nn34)CC2)cc1.O=C1CCCN1>>COc1ccc(C2(c3nnc4ncc(-c5ccc(N6CCCC6=O)cc5)nn34)CC2)cc1 -US07674802B2,2,CN.O=C(O)C1CCN(CCCOc2ccc(-n3nc4ccccc4c3Cl)cc2)CC1>>CNC(=O)C1CCN(CCCOc2ccc(-n3nc4ccccc4c3Cl)cc2)CC1 -US04616009,2,NC1CCN(Cc2ccccc2)CC1.O=C(O)c1c[nH]c2ccc(F)cc12>>O=C(NC1CCN(Cc2ccccc2)CC1)c1c[nH]c2ccc(F)cc12 -US20070021405A1,9,CC(C)(C)OC(=O)N1CCC(CC=C(Br)Br)CC1>>C#CCC1CCN(C(=O)OC(C)(C)C)CC1 -US08314108B2,6,COc1ccc(COc2cccc(OC)c2-c2cc(Nc3cnc(C#N)cn3)n[nH]2)cc1>>COc1cccc(O)c1-c1cc(Nc2cnc(C#N)cn2)n[nH]1 -US20110237565A1,1,C=O.CCOC(=O)c1cn2c(-c3cccs3)cnc(N3CCNCC3)c2n1>>CCOC(=O)c1cn2c(-c3cccs3)cnc(N3CCN(C)CC3)c2n1 -US08173650B2,1,CC(C)(C(N)=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1.Cc1nc2ccccc2[nH]1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2sc(CN3CCN(C(C)(C)C(N)=O)CC3)cc2n1 -US05990116,1,CI.COc1ccc(OC)c(CCc2ccc3nc[nH]c(=O)c3c2)c1>>COc1ccc(OC)c(CCc2ccc3ncn(C)c(=O)c3c2)c1 -US07745484B2,6,CC(C)(C)[S@](=O)N[C@@H](Cc1cc(F)cc(Cl)c1)[C@@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C>>CC(C)(C)[S@](=O)N[C@@H](Cc1cc(F)cc(Cl)c1)[C@@H](CO)O[Si](C)(C)C(C)(C)C -US20100216813A1,2,CS(=O)(=O)Cl.Cc1ccc(CO)s1>>Cc1ccc(COS(C)(=O)=O)s1 -US05059597,6,c1ccc(CN2CC3NCCOC3C2)cc1>>C1COC2CNCC2N1 -US05262415,7,O=[N+]([O-])c1cnccc1Nc1ccccc1>>Nc1cnccc1Nc1ccccc1 -US05736559,2,CCOC(=O)C1CCCNC1.N#Cc1ccc(-c2ccc(OCC(=O)O)cc2)cc1>>CCOC(=O)C1CCCN(C(=O)COc2ccc(-c3ccc(C#N)cc3)cc2)C1 -US20120059162A1,1,BrCC1CCCCC1.CSc1nc(NC(=O)OC(C)(C)C)cn2c(Br)cnc12>>CSc1nc(N(CC2CCCCC2)C(=O)OC(C)(C)C)cn2c(Br)cnc12 -US05932601,1,COc1cc(CCCC2OC(=O)NC2=O)ccc1O.ClCc1nc(-c2ccccc2)no1>>COc1cc(CCCC2OC(=O)NC2=O)ccc1OCc1nc(-c2ccccc2)no1 -US20140121206A1,1,COc1ccc(CN2CC3(CCCC(COCc4ccccc4)(COS(C)(=O)=O)C3)OC2=O)cc1.[N-]=[N+]=[N-]>>COc1ccc(CN2CC3(CCCC(CN=[N+]=[N-])(COCc4ccccc4)C3)OC2=O)cc1 -US09073947B2,2,CN(C)C/C=C/C(=O)O.Nc1cccc(-c2cnccc2Oc2ccc(Oc3ccccc3)cc2)c1>>CN(C)C/C=C/C(=O)Nc1cccc(-c2cnccc2Oc2ccc(Oc3ccccc3)cc2)c1 -US04939140,6,CCOC(=O)Cc1nn(C(c2ccccn2)c2ncno2)c(=O)c2ccccc12>>O=C(O)Cc1nn(C(c2ccccn2)c2ncno2)c(=O)c2ccccc12 -US04123544,2,CC(=O)Oc1ccccc1C(=O)Cl.O=C(O)[C@@H]1CC(O)CN1>>CC(=O)Oc1ccccc1C(=O)N1CC(O)C[C@H]1C(=O)O -US06624218B2,2,Nc1ccc(O)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccc(O)cc1)c1ccccc1 -US20120108611A1,1,CCOC(=O)c1ccc(-c2c(OC)cccc2OC)c(-c2ccc(Cl)c(O)c2)n1.CN1CCC(O)C1>>CCOC(=O)c1ccc(-c2c(OC)cccc2OC)c(-c2ccc(Cl)c(OC3CCN(C)C3)c2)n1 -US20120316147A1,2,CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)O.FC1(F)CNC1>>CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)N1CC(F)(F)C1 -US04973721,1,CC(=O)O[C@H]1C[C@H](OC(C)=O)CC2=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)[C@H](O)C#CC(C)(C)OC5CCCCO5)[C@@]4(C)CC[C@@H]3[C@]21C.CI>>CO[C@H](C#CC(C)(C)OC1CCCCO1)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)C[C@H](OC(C)=O)[C@]4(C)[C@H]3CC[C@]12C -US20090054451A1,1,N#Cc1ccc(CC(=O)NC2CCN(CCCl)CC2)cc1.Nc1ccccc1>>N#Cc1ccc(CC(=O)NC2CCN(CCNc3ccccc3)CC2)cc1 -US07872003B2,1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)CCCCl)CC1.CNC>>CN(C)CCCS(=O)(=O)N1CCN(C(=O)OC(C)(C)C)CC1 -US08822689B2,2,CC(N)(C#N)Cn1nc2cccc(Cl)c2n1.O=C(Cl)c1ccc(Oc2ccccc2)cc1>>CC(C#N)(Cn1nc2cccc(Cl)c2n1)NC(=O)c1ccc(Oc2ccccc2)cc1 -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1cc(NS(C)(=O)=O)cc(C)c1C=O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(NS(C)(=O)=O)cc1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US20080255114A1,6,CC[C@H]1COC[C@H](C)N1C(=O)OC(C)(C)C>>CC[C@H]1COC[C@H](C)N1 -US20140294898A1,5,COc1ccc2c(O[C@H]3CN[C@H](C(=O)O)C3)nccc2c1.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>COc1ccc2c(O[C@@H]3C[C@@H](C(=O)O)N(C(=O)OCC4c5ccccc5-c5ccccc54)C3)nccc2c1 -US20060172999A1,1,CC1(C)OCC2(CCNCC2)C1O.C[C@@H](O[C@H]1OCC[C@@H](C=O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1OCC[C@@H](CN2CCC3(CC2)COC(C)(C)C3O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US05688946,5,CC(C)(C)OC(=O)NCCN[C@@H](CC(=O)OCc1ccccc1)C(=O)OC(C)(C)C.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCN(C(=O)OC(C)(C)C)[C@@H](CC(=O)OCc1ccccc1)C(=O)OC(C)(C)C -US20130064770A1,6,CC(C)(C)OC(=O)N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1>>O=C1c2ccccc2C(=O)N1CCCCN1CCNCC1 -US20110009622A1,2,CC(C)c1ccc(N)cc1.COc1ccc(S(=O)(=O)N2CCCCC2)cc1C(=O)O>>COc1ccc(S(=O)(=O)N2CCCCC2)cc1C(=O)Nc1ccc(C(C)C)cc1 -US20100197692A1,6,CCOC(=O)CSc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2[nH]1>>O=C(O)CSc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2[nH]1 -US20090163462A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(I)cc1.Oc1ccc(-c2nccs2)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(Oc2ccc(-c3nccs3)cc2)cc1 -US20100280013A1,6,C/C=C\c1cc(C(=O)OC)ccc1N1CCN(C(=O)OC(C)(C)C)CC1>>C/C=C\c1cc(C(=O)O)ccc1N1CCN(C(=O)OC(C)(C)C)CC1 -US07622474B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc([N+](=O)[O-])cn1>>CC(C)(C)OC(=O)Nc1ccc([N+](=O)[O-])cn1 -US20090093484A1,3,C#CCN(C)C.CCOC(=O)/C=C(/c1ccccc1)c1ccc(Br)cc1>>CCOC(=O)/C=C(/c1ccccc1)c1ccc(C#CCN(C)C)cc1 -US20150191464A1,2,CC(C)(O)[C@H](F)CN.CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)O>>CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NC[C@@H](F)C(C)(C)O -US05736539,2,CC(C)(C)OC(=O)N1CCNC[C@@H]1CCO.O=C(O)c1cccc2cccnc12>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc3cccnc23)C[C@@H]1CCO -US08003785B2,1,CCN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21.COc1cc(C(=O)O)ccc1N>>CCN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)O)cc3OC)ncc21 -US20120295882A1,1,CC12CCNCC1Oc1ccc(OS(=O)(=O)Cc3ccccc3)cc12.CCBr>>CCN1CCC2(C)c3cc(OS(=O)(=O)Cc4ccccc4)ccc3OC2C1 -US08519135B2,6,CCN(C(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1)c1nn(C(=O)OC(C)(C)C)c2ccccc12>>CCN(C(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1)c1n[nH]c2ccccc12 -US20130158031A1,6,Cn1cc(-c2ccncn2)c(-c2ccc(C#C[Si](C)(C)C)cc2)n1>>C#Cc1ccc(-c2nn(C)cc2-c2ccncn2)cc1 -US05990105,1,CNc1nc(Br)cc(Br)n1.O=[N+]([O-])c1ccc(S)cc1>>CNc1nc(Br)cc(Sc2ccc([N+](=O)[O-])cc2)n1 -US08501732B2,6,COC(=O)c1c(C)c(=O)c2ccc(Cl)cc2n1-c1ccccc1>>Cc1c(C(=O)O)n(-c2ccccc2)c2cc(Cl)ccc2c1=O -US20110124618A1,6,CCOC(=O)c1cc(-c2cc(C)cc(F)c2)n(-c2ccc(F)c(Cl)c2)n1>>Cc1cc(F)cc(-c2cc(C(=O)O)nn2-c2ccc(F)c(Cl)c2)c1 -US20120252805A1,3,Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(Br)c(C)sc2n1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)o1>>Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(-c3ccc(C)o3)c(C)sc2n1 -US08299085B2,7,CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccc(C=O)c3)cc2c1=O>>CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccc(CO)c3)cc2c1=O -US20110190285A1,2,Cc1c(-c2ccc(Cl)cc2)n[nH]c1N.O=C(O)CS>>Cc1c(-c2ccc(Cl)cc2)n[nH]c1NC(=O)CS -US20090221555A1,1,CC1(C)CCC(=O)Nc2ccc(N)cc21.Cn1ccnc1-c1ccccc1Nc1nc(Cl)ncc1Cl>>Cn1ccnc1-c1ccccc1Nc1nc(Nc2ccc3c(c2)C(C)(C)CCC(=O)N3)ncc1Cl -US06114532,1,COC(=O)CN(c1ccc2c(c1)nc(Cc1ccc(C(=N)N)cc1)n2C)S(=O)(=O)c1cccc2cccnc12.COC(=O)Cl>>COC(=O)CN(c1ccc2c(c1)nc(Cc1ccc(C(N)=NC(=O)OC)cc1)n2C)S(=O)(=O)c1cccc2cccnc12 -US20090099199A1,2,Cc1noc(C)c1N=C=O.Nc1ccc(N2CCC(C(c3ccccc3)c3ccccc3)CC2)c(F)c1>>Cc1noc(C)c1NC(=O)Nc1ccc(N2CCC(C(c3ccccc3)c3ccccc3)CC2)c(F)c1 -US04426382,2,CCC=CC(=O)Cl.COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC>>CCC=CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 -US20060217380A1,2,NCCN1CCOCC1.O=C(O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>O=C(NCCN1CCOCC1)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1 -US20060025474A1,6,CCC(CC)(c1ccc(C#CCCCC(=O)OC)c(C)c1)c1ccc(C#CC(O)(C(F)(F)F)C(F)(F)F)c(C)c1>>CCC(CC)(c1ccc(C#CCCCC(=O)O)c(C)c1)c1ccc(C#CC(O)(C(F)(F)F)C(F)(F)F)c(C)c1 -US08362063B2,3,Brc1ccc2cc[nH]c2c1.CON(C)C(=O)c1ccc(F)c(S(N)(=O)=O)c1>>NS(=O)(=O)c1cc(C(=O)c2ccc3cc[nH]c3c2)ccc1F -US20030092712A1,6,CC1CN(C(=O)OC(C)(C)C)CCN1Cc1cc(-c2ccccc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)NC2>>CC1CNCCN1Cc1cc(-c2ccccc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)NC2 -US04820727,1,CC(C)(C)OC(=O)CBr.CCOC(=O)NC(=O)c1c(OCC(F)(F)F)ccc2c(C(F)(F)F)c(OC)ccc12>>CCOC(=O)N(CC(=O)OC(C)(C)C)C(=O)c1c(OCC(F)(F)F)ccc2c(C(F)(F)F)c(OC)ccc12 -US07576104B2,2,CC1(N2C(=O)c3cccc(N)c3C2=O)CCC(=O)NC1=O.CCCCC(=O)Cl>>CCCCC(=O)Nc1cccc2c1C(=O)N(C1(C)CCC(=O)NC1=O)C2=O -US07229987B2,2,CCOC(=O)Nc1ccc(-c2cnc(COCc3cc4ccccc4o3)o2)cc1.NCCN1CCCCC1>>O=C(NCCN1CCCCC1)Nc1ccc(-c2cnc(COCc3cc4ccccc4o3)o2)cc1 -US20150182509A1,1,CCN1CCc2[nH]c3ccc(C)cc3c2C1.ClCc1ccccc1>>CCN1CCc2c(c3cc(C)ccc3n2Cc2ccccc2)C1 -US06177587B1,1,CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US07557213B2,1,BrCc1cccc(Br)c1.O=C(c1ccc2c(c1)OCCO2)c1c[nH]c2ccccc2c1=O>>O=C(c1ccc2c(c1)OCCO2)c1cn(Cc2cccc(Br)c2)c2ccccc2c1=O -US20150203472A1,3,Brc1ccc2ncn(-c3ccncc3)c2c1.OB(O)c1ccnn1-c1ccc(Cl)cc1>>Clc1ccc(-n2nccc2-c2ccc3ncn(-c4ccncc4)c3c2)cc1 -US20060106027A1,6,CN1CCC(COc2cccc(NC(=O)OC(C)(C)C)c2)CC1>>CN1CCC(COc2cccc(N)c2)CC1 -US07713994B2,8,OCc1ccc2cc[nH]c2c1>>O=Cc1ccc2cc[nH]c2c1 -US20060287300A1,1,BrCc1ccccc1.COC1=CC(=O)C(O)(CCC(C)C)c2ccccc21>>COC1=CC(=O)C(CCC(C)C)(OCc2ccccc2)c2ccccc21 -US07160877B2,6,CCOC(=O)c1cnc(N(C)C)nc1O[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1>>CN(C)c1ncc(C(=O)O)c(O[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)n1 -US20150018547A1,6,COC(=O)Cc1csc2cc(OCc3ccc(C(F)(F)F)nc3C)cc(F)c12>>Cc1nc(C(F)(F)F)ccc1COc1cc(F)c2c(CC(=O)O)csc2c1 -US07910592B2,7,COC(=O)c1nc(SC)ncc1Br>>CSc1ncc(Br)c(CO)n1 -US04713455,4,C=CCCn1cnc2c1c(=O)n(CCCC)c(=O)n2CCCC.O=C(OO)c1cccc(Cl)c1>>CCCCn1c(=O)c2c(ncn2CCC2CO2)n(CCCC)c1=O -US05981533,1,Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12.O=Cc1cccc(Cl)c1>>Clc1cccc(CNc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)c1 -US06723716B1,1,CC(C)(C)OC(=O)NCCNc1nc(CCl)cs1.CC(C)(C)OC(=O)NCCS>>CC(C)(C)OC(=O)NCCNc1nc(CSCCNC(=O)OC(C)(C)C)cs1 -US20110212956A1,2,O=C(O)c1cc2ncc(Br)cn2n1.c1cc(-c2ccc3c(c2)CCNC3)ccn1>>O=C(c1cc2ncc(Br)cn2n1)N1CCc2cc(-c3ccncc3)ccc2C1 -US04215047,2,Cc1cc(=O)oc2cc(NC(=O)[C@@H](N)CCCNC(=N)N)ccc12.O=C(O)CNC(=O)OCc1ccccc1>>Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)OCc3ccccc3)ccc12 -US06369075B1,2,COc1ccccc1CN.O=C(O)c1cnc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1>>COc1ccccc1CNC(=O)c1cnc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1 -US20080090834A1,6,C[Si](C)(C)C#Cc1cc(F)cnc1N>>C#Cc1cc(F)cnc1N -US20080261921A1,2,CNC.O=C(O)Cc1cncc(Br)c1>>CN(C)C(=O)Cc1cncc(Br)c1 -US20100125085A1,7,Cc1ccc2c(c1)c1c(n2C=Cc2ccc(C)nc2)CCN(C(=O)OC(C)(C)C)C1>>Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(C(=O)OC(C)(C)C)C1 -US04880809,2,COc1cc(CN2CCNCC2)cc(OC)c1OC.O=C(O)C1=Cc2ccc(OCc3ccccc3)cc2CC1>>COc1cc(CN2CCN(C(=O)C3=Cc4ccc(OCc5ccccc5)cc4CC3)CC2)cc(OC)c1OC -US08450304B2,2,CC(C)(C)OC(=O)N1CC(N)C1.O=C(O)CNC(=O)c1cc(F)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CC(NC(=O)CNC(=O)c2cc(F)cc(C(F)(F)F)c2)C1 -US05037829,6,COC(OC)c1cc(C(c2ccccc2)n2ccnc2)ccc1NC(C)=O>>CC(=O)Nc1ccc(C(c2ccccc2)n2ccnc2)cc1C=O -US20080139564A1,7,CN(C)CCC(=O)c1ccc(OCCCN2CCCCC2)cc1>>CN(C)CCC(O)c1ccc(OCCCN2CCCCC2)cc1 -US08541584B2,6,Cn1cc(-c2cnc3c(c2)c(-c2cn(Cc4ccccc4)nn2)cn3C(=O)OC(C)(C)C)cn1>>Cn1cc(-c2cnc3[nH]cc(-c4cn(Cc5ccccc5)nn4)c3c2)cn1 -US20090069305A1,6,CC(C)(C)OC(=O)N1CCN(c2ncnc(-c3ccsc3)n2)CC1>>c1nc(-c2ccsc2)nc(N2CCNCC2)n1 -US20030087952A1,7,CCOC(=O)C1C(c2ccccc2)=CC(=O)N1[C@@H](C)c1ccc(OC)cc1>>CCOC(=O)[C@H]1[C@@H](c2ccccc2)CC(=O)N1[C@@H](C)c1ccc(OC)cc1 -US05663334,1,Cc1cc(C=O)ccn1.NCC1CC1>>Cc1cc(C=NCC2CC2)ccn1 -US20090163508A1,2,Fc1cccc(-c2ccnc(N3CCNCC3)n2)c1.O=C(Nc1cccnc1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnc1)N1CCN(c2nccc(-c3cccc(F)c3)n2)CC1 -US07348017B2,1,COC(=O)C(O)c1ccc(OCc2ccc(F)cc2)cc1.COCCOCCl>>COCCOCOC(C(=O)OC)c1ccc(OCc2ccc(F)cc2)cc1 -US20100204196A1,2,Cc1ccc(N)cc1[N+](=O)[O-].O=C(Cl)CCl>>Cc1ccc(NC(=O)CCl)cc1[N+](=O)[O-] -US20130116322A1,6,C=C(CCNC(=O)OC(C)(C)C)c1c(C)c(CC(=O)OC)cc2ccc(F)cc12>>C=C(CCN)c1c(C)c(CC(=O)OC)cc2ccc(F)cc12 -US20140162983A1,2,CNOC.Nc1ncnc(Nc2ccc(CC(=O)O)cc2)c1-c1ccc(Oc2ccccc2)cc1>>CON(C)C(=O)Cc1ccc(Nc2ncnc(N)c2-c2ccc(Oc3ccccc3)cc2)cc1 -US20150087639A1,1,O=[N+]([O-])c1ccc(F)c(F)c1.OCCN1CCOCC1>>O=[N+]([O-])c1ccc(OCCN2CCOCC2)c(F)c1 -US20100286215A1,9,COC(=O)c1cc(C(=O)c2ccc(NC(=O)c3cccc(Cl)c3)cc2)ccc1F.[N-]=[N+]=[N-]>>COC(=O)c1cc(C(=O)c2ccc(NC(=O)c3cccc(Cl)c3)cc2)ccc1N=[N+]=[N-] -US20090018134A1,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C(C)(C)C)CC2)nc(Cl)n1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C(C)(C)C)CC2)nc(-c2ccc(N)cc2)n1 -US06143764,2,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C(O)C1CCCC1>>COc1cc2nccc(Oc3ccc(NC(=O)C4CCCC4)cc3)c2cc1OC -US20110212968A1,3,COC(=O)c1ncccc1Br.COc1ccc(B(O)O)cn1>>COC(=O)c1ncccc1-c1ccc(OC)nc1 -US20130245015A1,2,CCc1cc(Br)ccc1N.Cc1ccc(F)c(N=C=O)c1>>CCc1cc(Br)ccc1NC(=O)Nc1cc(C)ccc1F -US20130261128A1,4,COC(=O)C(C)(C)COc1cc(C)c(-c2ccc(C(=N)N)c(F)c2)cn1.O=C(CBr)CC1CC1>>COC(=O)C(C)(C)COc1cc(C)c(-c2ccc(-c3ncc(CC4CC4)[nH]3)c(F)c2)cn1 -US20080306045A1,2,CC(C)(C)OC(=O)N1CCCc2c(ccc(N3CC[C@H](N)C3=O)c2F)C1.O=S(=O)(Cl)c1ccc2cc(Cl)ccc2c1>>CC(C)(C)OC(=O)N1CCCc2c(ccc(N3CC[C@H](NS(=O)(=O)c4ccc5cc(Cl)ccc5c4)C3=O)c2F)C1 -US06362181B1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1.N#Cc1cc2c3c(cccc3c1Cl)C(=O)N(OCc1ccccc1)C2=O>>CC(C)(C)OC(=O)N[C@H]1CCN(c2c(C#N)cc3c4c(cccc24)C(=O)N(OCc2ccccc2)C3=O)C1 -US08946260B2,1,Cc1ccncc1I.O=c1[nH]ccc2ccc(C(F)(F)F)cc12>>Cc1ccncc1-n1ccc2ccc(C(F)(F)F)cc2c1=O -US07368578B2,6,CCOP(=O)(/C=C/c1cn(-c2ccccc2)nc1OCc1ccc(OCc2nc(-c3cccc(C(=O)OC)c3)oc2C)c(OC)c1)OCC>>CCOP(=O)(/C=C/c1cn(-c2ccccc2)nc1OCc1ccc(OCc2nc(-c3cccc(C(=O)O)c3)oc2C)c(OC)c1)OCC -US20040171604A1,1,CCOC(=O)c1ncc(C(=O)OC(C)(C)C)[nH]1.Clc1ccc(-c2cc(CBr)no2)s1>>CCOC(=O)c1ncc(C(=O)OC(C)(C)C)n1Cc1cc(-c2ccc(Cl)s2)on1 -US20080312234A1,2,CS(=O)(=O)Nc1c(F)cc(CN)cc1C#N.O=C(O)C=Cc1ccc(C(F)(F)F)nc1-c1cccc(F)c1>>CS(=O)(=O)Nc1c(F)cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2-c2cccc(F)c2)cc1C#N -US20090036434A1,1,CCOC(=O)CN1CCNCC1.Clc1cc(Cl)ncn1>>CCOC(=O)CN1CCN(c2cc(Cl)ncn2)CC1 -US20040132769A1,2,CC(C)O.O=C(O)Cc1cc(C(F)(F)F)ccc1I>>CC(C)OC(=O)Cc1cc(C(F)(F)F)ccc1I -US04912231,1,BrCc1ccccc1.O=C(O)[C@@H]1C[C@H](O)CN1C(=O)c1ccccc1>>O=C(OCc1ccccc1)[C@@H]1C[C@H](O)CN1C(=O)c1ccccc1 -US06384051B1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Cc1c(N)cccc1O>>COc1cc2ncc(C#N)c(Nc3cccc(O)c3C)c2cc1OC -US20080234335A1,9,CC1(C)OB(C2=C(c3cc(C(F)(F)F)ccc3OCc3ccccc3)CCCC2)OC1(C)C>>OB(O)C1=C(c2cc(C(F)(F)F)ccc2OCc2ccccc2)CCCC1 -US05352719,2,CCCCCCCCCCCCOC(=O)CCN1C(=O)C2(CC(C)(C)NC(C)(C)C2)OC12CCCCCCCCCCC2.NN>>CC1(C)CC2(CC(C)(C)N1)OC1(CCCCCCCCCCC1)N(CCC(=O)NN)C2=O -US08889741B2,7,O=[N+]([O-])c1n[nH]cc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)c(F)c1>>Nc1n[nH]cc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)c(F)c1 -US20140329803A1,2,CC(C)CN.CCOC(=O)N1CCCC(N2CCC(C(=O)O)CC2)CC1>>CCOC(=O)N1CCCC(N2CCC(C(=O)NCC(C)C)CC2)CC1 -US20120035168A1,6,COC(=O)c1cn(Cc2ccc(Cn3cccn3)cc2)cn1>>O=C(O)c1cn(Cc2ccc(Cn3cccn3)cc2)cn1 -US20090270431A1,8,C=CC(O[Si](C)(C)C(C)(C)C)C1OC(C)(C)OC1C(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1>>C=CC(O[Si](C)(C)C(C)(C)C)C1OC(C)(C)OC1C(=O)COC(c1ccccc1)(c1ccccc1)c1ccccc1 -US04960936,7,O=[N+]([O-])c1cccc(Cl)c1Cl>>Nc1cccc(Cl)c1Cl -US20070203196A1,1,CNC(=O)c1ccccc1S.Ic1ccc2c(I)n[nH]c2c1>>CNC(=O)c1ccccc1Sc1ccc2c(I)n[nH]c2c1 -US07410985B2,2,Cc1cc(=O)c(OCc2ccccc2)c(C(=O)O)o1.NC1CCC1>>Cc1cc(=O)c(OCc2ccccc2)c(C(=O)NC2CCC2)o1 -US05736540,1,CNC.O=C(Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1)C(Cl)c1ccccc1>>CN(C)C(C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1)c1ccccc1 -US08754068B2,3,C=C(C)[C@@H]1CC[C@]2(COC(=O)c3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CCCC[Sn](CCCC)(CCCC)c1cc(C(=O)OCC)no1>>C=C(C)[C@@H]1CC[C@]2(COC(=O)c3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6cc(C(=O)OCC)no6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20060223850A1,3,CON(C)C(=O)c1nc(-c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c(-c2ccc(SC)cc2)s1.C[Mg+]>>CSc1ccc(-c2sc(C(C)=O)nc2-c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)cc1 -USRE040558E1,7,Cc1cccc(C=O)c1OCC#N>>Cc1cccc(CO)c1OCC#N -US20070010511A1,10,COC(=O)c1cc2cccc(C)c2o1.O=C1CCC(=O)N1Br>>COC(=O)c1cc2cccc(CBr)c2o1 -US04421757,6,CC(=O)Oc1ccc(N=c2scc(-c3ccc(Cl)c(S(=O)(=O)N(C)C)c3)n2C)cc1>>CN(C)S(=O)(=O)c1cc(-c2csc(=Nc3ccc(O)cc3)n2C)ccc1Cl -US04046900,1,BrCCc1c[nH]c2ccccc12.O=C(c1ccc(O)cc1)C1CCNCC1>>O=C(c1ccc(O)cc1)C1CCN(CCc2c[nH]c3ccccc23)CC1 -US07148226B2,6,COCc1cc(CCC2(C3CCCC3)CC(=O)CC(=O)O2)ccc1O>>O=C1CC(=O)OC(CCc2ccc(O)c(CO)c2)(C2CCCC2)C1 -US08691988B2,3,Cc1ccccc1B(O)O.Nc1ccccc1Br>>Cc1ccccc1-c1ccccc1N -US09085583B2,2,Cc1c(C(=O)O)c2ccccc2n1C(=O)c1ccccc1.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2c(C)n(C(=O)c3ccccc3)c3ccccc23)c(O)n1 -US07737149B2,1,COc1cc(CCc2cc(NC(=O)c3cnc(Cl)cn3)[nH]n2)cc(OC)c1.C[C@H]1CNC[C@@H](C)N1CC#N>>COc1cc(CCc2cc(NC(=O)c3cnc(N4C[C@H](C)N(CC#N)[C@H](C)C4)cn3)[nH]n2)cc(OC)c1 -US20130303538A1,2,CCCN(CCC)C(=O)CCCC(=O)O.COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1>>CCCN(CCC)C(=O)CCCC(=O)O[C@@]1(C#Cc2cccc(C)c2)CCC[C@@H]2[C@H]1CCN2C(=O)OC -US07932247B2,7,CC(C)(C)OC(=O)N1CCN(Cc2cccc(-c3cccc(C#N)c3)c2)CC1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(-c3cccc(CN)c3)c2)CC1 -US05344843,1,COC(=O)C(=O)c1ccc(O)cc1.OCCCCSc1ccc2ccccc2c1>>COC(=O)C(=O)c1ccc(OCCCCSc2ccc3ccccc3c2)cc1 -US20090023785A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1Cc2ccc(O)cc2C1>>CC(C)(C)OC(=O)NC1Cc2ccc(O)cc2C1 -US07148234B2,1,CC(=O)c1cnc(Cl)c([N+](=O)[O-])c1.C[C@H](O)Cc1ccc(N)cc1>>CC(=O)c1cnc(Nc2ccc(C[C@H](C)O)cc2)c([N+](=O)[O-])c1 -US20130116243A1,1,C#CCBr.CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=O)CO4)cc2)CCC1>>C#CCN1C(=O)COc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc21 -US20100075978A1,2,NCCc1ccc(C2=NCCN2)cc1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2)cc1>>O=C(NCCc1ccc(C2=NCCN2)cc1)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2)cc1 -US20040242928A1,7,COC(=O)C=C1CCN(C(=O)OC(C)(C)C)CC1(C)C>>CC(C)(C)OC(=O)N1CCC(=CCO)C(C)(C)C1 -US04959482,2,CC(C)(C)c1cc(N)cc(C(C)(C)C)c1O.O=C(Cl)CCCCl>>CC(C)(C)c1cc(NC(=O)CCCCl)cc(C(C)(C)C)c1O -US20100120784A1,1,OCCCBr.Oc1cc(F)ccc1Br>>OCCCOc1cc(F)ccc1Br -US20060264460A1,1,CN(C)c1ccc(C=O)c(F)c1C#N.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>CN(C)c1ccc(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)c(F)c1C#N -US20100041891A1,2,CCOC(=O)c1cccc(-c2ccc(F)c3cc(Cc4cccc(S(C)(=O)=O)c4)sc23)c1.COCCN>>COCCNC(=O)c1cccc(-c2ccc(F)c3cc(Cc4cccc(S(C)(=O)=O)c4)sc23)c1 -US20120071616A1,7,Cc1cc(C)c(N=Cc2cccc(-c3c(CNC(C)(C)C)ccc4ccccc34)n2)c(C)c1>>Cc1cc(C)c(NCc2cccc(-c3c(CNC(C)(C)C)ccc4ccccc34)n2)c(C)c1 -US20130274469A1,7,CCOC(=O)c1c(-c2ccc(Cl)cc2F)noc1C>>Cc1onc(-c2ccc(Cl)cc2F)c1CO -US07414060B2,2,CC(C)(C)[SiH2]OC(C)(C)c1csc(N)n1.CCOC(=O)c1nc(C)ccc1Nc1cncnc1>>Cc1ccc(Nc2cncnc2)c(C(=O)Nc2nc(C(C)(C)O[SiH2]C(C)(C)C)cs2)n1 -US08822497B2,2,CC(C)(C)OC(=O)N[C@@H]1CN(c2ccncc2N)CC[C@H]1O[Si](C)(C)C(C)(C)C.Nc1ccc(-c2c(F)cccc2F)nc1C(=O)O>>CC(C)(C)OC(=O)N[C@@H]1CN(c2ccncc2NC(=O)c2nc(-c3c(F)cccc3F)ccc2N)CC[C@H]1O[Si](C)(C)C(C)(C)C -US20070232615A1,7,O=Cc1cn2c(Br)cccc2n1>>OCc1cn2c(Br)cccc2n1 -US06939874B2,1,Clc1ccnc(Cl)n1.Nc1ccccn1>>Clc1nccc(Nc2ccccn2)n1 -US08461348B2,4,CCOC(=O)c1cnn(CC(N)=S)c1.O=C(CBr)c1cccc(C(F)(F)F)c1>>CCOC(=O)c1cnn(Cc2nc(-c3cccc(C(F)(F)F)c3)cs2)c1 -US20080171743A1,2,CC(C)S(=O)(=O)Cc1cc(N2CCOC[C@@H]2C)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>CC(C)S(=O)(=O)Cc1cc(N2CCOC[C@@H]2C)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US20110077399A1,2,CC(C)(C)CCN.COc1ccc(-c2ccc(/C=C/c3nc(-c4ccc(Cl)cc4Cl)cn3CC(=O)O)cc2)cc1>>COc1ccc(-c2ccc(/C=C/c3nc(-c4ccc(Cl)cc4Cl)cn3CC(=O)NCCC(C)(C)C)cc2)cc1 -US20110092505A1,9,CC(C)(C)OC(=O)N1CCN(c2cc(CBr)cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCN(c2cc(CN=[N+]=[N-])cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1 -US20020068753A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(O)CC1 -US20040097503A1,1,COc1ccc(Cl)c(N)c1.FC(F)(F)c1cc(Cl)nc(-c2ccccn2)n1>>COc1ccc(Cl)c(Nc2cc(C(F)(F)F)nc(-c3ccccn3)n2)c1 -US04371389,7,CCOC(=O)c1sc(Cl)nc1-c1ccc(Cl)cc1>>OCc1sc(Cl)nc1-c1ccc(Cl)cc1 -US20150057265A1,2,CC(C)c1cnc2c(C(=O)O)c(NC(=O)OC(C)(C)C)oc2c1.C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)C[C@H](c2ccncc2N)C1>>CC(C)c1cnc2c(C(=O)Nc3cnccc3[C@H]3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)c(NC(=O)OC(C)(C)C)oc2c1 -US20080119488A1,3,CCOC(=O)c1cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2[nH]1.Cc1ccc(Cn2c(-c3cccc(Br)n3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1>>CCOC(=O)c1cc2ccc(-c3cccc(-c4cc(C(F)(F)F)c(C#N)c(=O)n4Cc4ccc(C)cc4C)n3)cc2[nH]1 -US05244908,1,O=C1c2ccccc2C(=O)N1CCCCCCBr.Sc1cccc2nccn12>>O=C1c2ccccc2C(=O)N1CCCCCCSc1cccc2nccn12 -US20120004197A1,1,CC(=O)N1c2cc(F)ccc2[C@@H](O)C[C@@H]1C.Oc1ccccc1>>CC(=O)N1c2cc(F)ccc2[C@H](Oc2ccccc2)C[C@@H]1C -US20120245344A1,7,CC(C)(C)OC(=O)N1CCC(c2ccc(Cn3ccc4cc(S(C)(=O)=O)cc([N+](=O)[O-])c43)nc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(Cn3ccc4cc(S(C)(=O)=O)cc(N)c43)nc2)CC1 -US08299085B2,1,CNC.CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc2c1=O>>CN(C)c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1[N+](=O)[O-] -US20090239810A1,2,Clc1ncccc1OC1CCNCC1.O=C(O)CNC(=O)c1cc(-c2ccc(F)cc2)on1>>O=C(NCC(=O)N1CCC(Oc2cccnc2Cl)CC1)c1cc(-c2ccc(F)cc2)on1 -US20090105225A1,6,CC(C)(C)OC(=O)NCCCCN1CCCC(n2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)CC1>>NCCCCN1CCCC(n2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)CC1 -US07291631B2,2,Cc1cccnc1CN(CCCN)C(C)c1ccccn1.O=C(O)c1ccc(O)nc1>>Cc1cccnc1CN(CCCNC(=O)c1ccc(O)nc1)C(C)c1ccccn1 -US07732446B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cnc(CN)c2cc(OC)c(OC)cc12>>CCOC(=O)c1cnc(CNC(=O)OC(C)(C)C)c2cc(OC)c(OC)cc12 -US06964961B2,2,O=C([O-])c1cc2nccc(Cl)c2s1.OC1CCNC1>>O=C(c1cc2nccc(Cl)c2s1)N1CCC(O)C1 -US04390536,7,O=C(CN1CCC(N2Cc3ccccc3OC2=O)CC1)c1ccc2c(c1)OCO2>>O=C1Oc2ccccc2CN1C1CCN(CC(O)c2ccc3c(c2)OCO3)CC1 -US20060160794A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ccccc1C1CCCN1>>CC(C)(C)OC(=O)N1CCCC1c1ccccc1Cl -US07304064B2,1,CI.COc1cccc2c(C(=O)N3CCN[C@@H](C)C3)cn(CC3CCCCC3)c12>>COc1cccc2c(C(=O)N3CCN(C)[C@@H](C)C3)cn(CC3CCCCC3)c12 -US20150232463A1,7,Cc1ccc(CC(=O)O)s1>>Cc1ccc(CCO)s1 -US20150065534A1,6,COC(=O)c1cc(O)cc(OCCCNC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)NCCCOc1cc(O)cc(C(=O)O)c1 -US06943183B2,1,CC(C)CO.O=C1CCCc2c1ccc(O)c2CCl>>CC(C)COCc1c(O)ccc2c1CCCC2=O -US08217051B2,2,CS(=O)(=O)Cl.OC1CCOCC1>>CS(=O)(=O)OC1CCOCC1 -US20150266857A1,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)c2ccc(F)cc21.O=c1[nH]c2ccc(Br)cc2o1>>CC(C)(C)OC(=O)n1cc(-c2ccc3[nH]c(=O)oc3c2)c2ccc(F)cc21 -US07179823B1,1,CCOC(=O)CCc1cn(Cc2ccc(O)cc2)cc1-c1ccccc1.Cc1sc(-c2ccccc2)nc1CCl>>CCOC(=O)CCc1cn(Cc2ccc(OCc3nc(-c4ccccc4)sc3C)cc2)cc1-c1ccccc1 -US08883809B2,1,COc1cc(C2NC(=O)c3ccccc3N2)ccc1OCCCCCBr.COc1ccc(-c2cc(-c3cc(OC)c(OC)c(OC)c3)on2)cc1O>>COc1cc(C2NC(=O)c3ccccc3N2)ccc1OCCCCCOc1cc(-c2cc(-c3cc(OC)c(OC)c(OC)c3)on2)ccc1OC -US20040138286A1,6,Cc1c(O[C@@H]2CCC[C@H](N(C)c3ccccc3)C2)ccc2c1cnn2C1CCCCO1>>Cc1c(O[C@@H]2CCC[C@H](N(C)c3ccccc3)C2)ccc2[nH]ncc12 -US20090197870A1,3,COc1cc(C(C)=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F.O=C1CSC(=S)N1>>COc1cc(C(C)=C2SC(=S)NC2=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F -US20030092699A1,2,CCCCN1CCC(CN)CC1.CCc1cn2c(N)c(Cl)cc(C(=O)O)c2n1>>CCCCN1CCC(CNC(=O)c2cc(Cl)c(N)n3cc(CC)nc23)CC1 -US20120149721A1,3,COC(=O)c1c(C)n(COCC[Si](C)(C)C)c2c(Cl)nc(C)nc12.Cc1ccc(OCC2CC2)c(B2OC(C)(C)C(C)(C)O2)c1>>COC(=O)c1c(C)n(COCC[Si](C)(C)C)c2c(-c3cc(C)ccc3OCC3CC3)nc(C)nc12 -US08993756B2,6,C=C(CNC(=O)OC(C)(C)C)C(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1>>C=C(CN)C(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1 -US20090023709A1,1,NCCCCO.O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl>>O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1NCCCCO -US08748421B2,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.CNC(=O)Nc1ccc(-c2nc(Cl)nc(N3CC4CCC(C3)O4)n2)cc1>>CNC(=O)Nc1ccc(-c2nc(-c3ccc(N)cc3)nc(N3CC4CCC(C3)O4)n2)cc1 -US20030073833A1,8,OCCc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F>>O=CCc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F -US20090215822A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](c2noc(-c3ccc(F)cc3)n2)C1>>Fc1ccc(-c2nc([C@@H]3CCCNC3)no2)cc1 -US20020045747A1,2,CN1C(=O)C(NC(=O)[C@@H](N)C(C)(C)C)N=C(c2ccccc2)c2ccccc21.O=C(O)Cc1cc(F)cc(F)c1>>CN1C(=O)C(NC(=O)[C@@H](NC(=O)Cc2cc(F)cc(F)c2)C(C)(C)C)N=C(c2ccccc2)c2ccccc21 -US20100105655A1,1,CC(=O)N1CCN(c2ccc(N)c(C#N)c2)CC1.Clc1ncc(Cl)c(-c2cnc3ccccn23)n1>>CC(=O)N1CCN(c2ccc(Nc3ncc(Cl)c(-c4cnc5ccccn45)n3)c(C#N)c2)CC1 -US05236927,1,C#CCNc1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)c(F)c1.CC(C)(C)C(=O)OCn1cnc2ccc(CBr)cc2c1=O>>C#CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)c(F)c1 -US05244908,2,CS(=O)(=O)Cl.c1ccc(NCCOCCCSc2cccc3nccn23)cc1>>CS(=O)(=O)N(CCOCCCSc1cccc2nccn12)c1ccccc1 -US20100292469A1,1,CN1CCOCC1.COc1nc(Cl)nc(OC)n1>>COc1nc(OC)nc([N+]2(C)CCOCC2)n1 -US08802860B2,2,Cc1cc(N2C[C@H](CN)OC2=O)cc(C)c1-n1cccc(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1=O.O=C(Cl)c1ccc(Cl)s1>>Cc1cc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc(C)c1-n1cccc(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1=O -US20150197511A1,6,CC(C)(C)OC(=O)N1CCC(C(=O)c2cc(Br)cc(C(F)(F)F)c2)CC1>>O=C(c1cc(Br)cc(C(F)(F)F)c1)C1CCNCC1 -US20050153984A1,2,CC(=O)OC(C)=O.Nc1nc2c(Oc3cncc(-c4ccc(C(F)(F)F)cc4)n3)cccc2s1>>CC(=O)Nc1nc2c(Oc3cncc(-c4ccc(C(F)(F)F)cc4)n3)cccc2s1 -US20150126485A1,1,NCCC(O)C(=O)O.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2ccn[nH]2)c1>>O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(NCCC(O)C(=O)O)c(-c2ccn[nH]2)c1 -US20130096149A1,2,CCCS(=O)(=O)Cl.CSc1nccc(-c2oc(C3CC3)nc2-c2cc(Cl)cc(N)c2Cl)n1>>CCCS(=O)(=O)Nc1cc(Cl)cc(-c2nc(C3CC3)oc2-c2ccnc(SC)n2)c1Cl -US05039805,2,CC(C)(C)OC(=O)NCCC(=O)O.Nc1ccc([N+](=O)[O-])c(C(=O)O)c1>>CC(C)(C)OC(=O)NCCC(=O)Nc1ccc([N+](=O)[O-])c(C(=O)O)c1 -US20060264460A1,1,COCCOc1ccc(Br)cc1C=O.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>COCCOc1ccc(Br)cc1CNc1ccc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1 -US20050085520A1,2,C[C@H](C[C@H](O)[C@@H](N)Cc1ccccc1)C(=O)NC1CC2CCC1C2.O=C(O)c1cc(N2CCCC2=O)cc(N2CCCC2=O)c1>>C[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(N2CCCC2=O)cc(N2CCCC2=O)c1)C(=O)NC1CC2CCC1C2 -US20060046990A1,7,COc1cc(N2CCC(N3CCCC3)CC2)ccc1[N+](=O)[O-]>>COc1cc(N2CCC(N3CCCC3)CC2)ccc1N -US08518972B2,1,O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1.c1ccc(OC2CCNCC2)cc1>>O=C1CCC(N2Cc3c(OCc4ccc(CN5CCC(Oc6ccccc6)CC5)cc4)cccc3C2=O)C(=O)N1 -US20140107340A1,2,Cc1ncc(C2(CN)CCOCC2)cn1.O=C(O)c1cccc(F)c1Cl>>Cc1ncc(C2(CNC(=O)c3cccc(F)c3Cl)CCOCC2)cn1 -US08648068B2,7,O=[N+]([O-])c1ccc(F)cc1OC1CCOCC1>>Nc1ccc(F)cc1OC1CCOCC1 -US08957252B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H](CO)C(=O)NCc1ccccc1>>CC(C)(C)OC(=O)N[C@H](CO)C(=O)NCc1ccccc1 -US20080004271A1,1,CSc1nc(Cl)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1.NC(=O)CS>>CSc1nc(SCC(N)=O)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1 -US20140058098A1,6,COCOc1cnc(Cl)cc1-c1ncc[nH]1>>Oc1cnc(Cl)cc1-c1ncc[nH]1 -US04921887,7,CC(=O)OC(C)(C)C(=O)Nc1nc(CN2CCC(OC(c3ccccc3)c3ccccc3)CC2)cs1>>CC(C)(O)C(=O)Nc1nc(CN2CCC(OC(c3ccccc3)c3ccccc3)CC2)cs1 -US20150023913A1,1,COC(=O)[C@@H](N)C(C)(C)C.ICCOCc1ccccc1>>COC(=O)[C@@H](NCCOCc1ccccc1)C(C)(C)C -US08383829B2,2,CC(C)(C)c1ccc(N)cc1.CCOC(=O)C(=O)Cl>>CCOC(=O)C(=O)Nc1ccc(C(C)(C)C)cc1 -US20120046300A1,1,C1CCNC1.COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OCC1CCN(C(=O)CCl)CC1>>COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OCC1CCN(C(=O)CN2CCCC2)CC1 -US20140275026A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#Cc1ccc(Oc2ccc(N)cc2Br)cc1>>CC1(C)OB(c2cc(N)ccc2Oc2ccc(C#N)cc2)OC1(C)C -US07517884B2,3,CCOC(=O)CP(=O)(OCC)OCC.COc1ccc2c(c1)C(=O)CC2>>CCOC(=O)C=C1CCc2ccc(OC)cc21 -US20080021217A1,6,CC(C)(C)OC(=O)NCc1nc(-c2c[nH]c3ncccc23)cs1>>NCc1nc(-c2c[nH]c3ncccc23)cs1 -US06376491B1,1,CCOC(=O)c1oc2cccc(OCCCNC3CCNCC3)c2c1C.ClCc1cccnc1>>CCOC(=O)c1oc2cccc(OCCCNC3CCN(Cc4cccnc4)CC3)c2c1C -US06248870B1,9,COc1ccc(-c2cc(-c3ccccn3)nc(-c3cccc(Br)n3)c2)cc1.[C-]#N>>COc1ccc(-c2cc(-c3ccccn3)nc(-c3cccc(C#N)n3)c2)cc1 -US04249012,9,CC(=O)Nc1csc(Br)n1>>CC(=O)Nc1cscn1 -US04939137,2,COC(=O)c1cscc1N.O=C=NCCCCBr>>COC(=O)c1cscc1NC(=O)NCCCCBr -US04970222,1,CCOC(=O)C(C)Br.Oc1ccc(Oc2cc(F)cc(F)c2)cc1>>CCOC(=O)C(C)Oc1ccc(Oc2cc(F)cc(F)c2)cc1 -US20100029641A1,2,CN.COC(=O)C(F)(F)CO>>CNC(=O)C(F)(F)CO -US20040138286A1,6,CCOC(=O)C1CCC(Oc2ccc3[nH]ncc3c2)CC1>>O=C(O)C1CCC(Oc2ccc3[nH]ncc3c2)CC1 -US08486953B2,2,CN(C)CCCN.COC(=O)c1sc2ncnc(Nc3ccc(C(F)(F)F)nc3OC3CCOCC3)c2c1C>>Cc1c(C(=O)NCCCN(C)C)sc2ncnc(Nc3ccc(C(F)(F)F)nc3OC3CCOCC3)c12 -US20150225379A1,6,CC(C)(C)OC(=O)N1CCC(CN[C@@H]2C[C@H]2c2ccccc2)(Cc2ccc(F)cc2)CC1>>Fc1ccc(CC2(CN[C@@H]3C[C@H]3c3ccccc3)CCNCC2)cc1 -US08338605B2,7,CC(=O)c1cccc(Oc2ccc(Cl)cc2[N+](=O)[O-])c1>>CC(O)c1cccc(Oc2ccc(Cl)cc2[N+](=O)[O-])c1 -US20080255094A1,1,O=C(NC(CCO)c1ccccc1)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1.Oc1ccccc1>>O=C(NC(CCOc1ccccc1)c1ccccc1)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 -US20150284384A1,2,Cc1cc(C(=O)O)cc2nc(C(C)(F)F)c(Cc3ccc(Cl)cc3)n12.NC1CCOCC1>>Cc1cc(C(=O)NC2CCOCC2)cc2nc(C(C)(F)F)c(Cc3ccc(Cl)cc3)n12 -US20150252022A1,2,O=C(Cl)c1ccccc1.c1cc2c(ccn2CC2CCCNCC2)cc1-c1cnn(C2CCCCO2)c1>>O=C(c1ccccc1)N1CCCC(Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CC1 -US08933085B2,6,COCc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)nc(C(F)(F)F)c1>>COCc1cc(OC2CCNCC2)nc(C(F)(F)F)c1 -US20050131014A1,1,Cc1cccc(O)c1C.OCc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>Cc1cccc(OCc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1C -US20070270421A1,2,CN(C)CC1CCN(C(=O)Nc2cc(Oc3ccc(N)cc3)ccn2)CC1.O=C=NC(=O)Cc1ccc(F)cc1>>CN(C)CC1CCN(C(=O)Nc2cc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3)ccn2)CC1 -US20100222352A1,1,Brc1ccccn1.Cc1ccc(N)cc1O>>Cc1ccc(Nc2ccccn2)cc1O -US20150051171A1,1,COc1ccccc1-n1ccc(O)n1.Cn1nnn(-c2cccc(C3CC3)c2CBr)c1=O>>COc1ccccc1-n1ccc(OCc2c(C3CC3)cccc2-n2nnn(C)c2=O)n1 -US20110178089A1,1,CCOC(=O)c1cncnc1Cl.Oc1cc(Cl)ccc1Cl>>CCOC(=O)c1cncnc1Oc1cc(Cl)ccc1Cl -US20090181942A1,3,C=CC(=O)OC(C)(C)C.Nc1ccc(Br)cn1>>CC(C)(C)OC(=O)/C=C/c1ccc(N)nc1 -US05250517,7,C=C[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(C)C>>CC[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(C)C -US20020028797A1,1,COc1ccc(NS(=O)(=O)c2ccc(N3CCC(=O)CC3)cc2)cc1OC.NCC(O)COc1cccc2[nH]c3ccccc3c12>>COc1ccc(NS(=O)(=O)c2ccc(N3CCC(NC[C@H](O)COc4cccc5[nH]c6ccccc6c45)CC3)cc2)cc1OC -US20140142084A1,7,Cc1cc([N+](=O)[O-])ccc1N1CCC(N2CCS(=O)(=O)CC2)CC1>>Cc1cc(N)ccc1N1CCC(N2CCS(=O)(=O)CC2)CC1 -US07553867B2,1,CCc1oc(-c2ccc(C(F)(F)F)cc2)cc1C(O)CCO[Si](C)(C)C(C)(C)C.CI>>CCc1oc(-c2ccc(C(F)(F)F)cc2)cc1C(CCO[Si](C)(C)C(C)(C)C)OC -US20100216810A1,7,COC(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(F)c(NC(=O)Cc2cccc(C(F)(F)F)c2)c1>>COC(=O)c1cc(N)ccc1Oc1ccc(F)c(NC(=O)Cc2cccc(C(F)(F)F)c2)c1 -US20070049603A1,3,Brc1cnc(I)nc1.CC(C)(C)[Si](Oc1c(Br)oc2cnccc12)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](Oc1c(-c2ncc(Br)cn2)oc2cnccc12)(c1ccccc1)c1ccccc1 -US05726205,1,C/C=C/C(=O)O.CN(C)Cc1ccc([C@@H]2CC[C@@H](O)CC2)cc1>>CC=CC(=O)O[C@@H]1CC[C@@H](c2ccc(CN(C)C)cc2)CC1 -US20150284411A1,6,CCOC(=O)CC1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@H]12>>O=C(O)CC1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@H]12 -US20130296312A1,3,COc1ccccc1Nc1nc2c(Br)cccn2n1.CS(=O)(=O)c1ccc(B(O)O)cc1>>COc1ccccc1Nc1nc2c(-c3ccc(S(C)(=O)=O)cc3)cccn2n1 -US20150051395A1,1,COC(=O)[C@H](Cc1ccc(Br)cn1)NC(=O)OC(C)(C)C.N=C(c1ccccc1)c1ccccc1>>COC(=O)[C@H](Cc1ccc(N=C(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C -US04958026,2,CCCC(=O)Cl.CCCN(CCC)CCc1ccc(N)c(OCc2ccccc2)c1>>CCCC(=O)Nc1ccc(CCN(CCC)CCC)cc1OCc1ccccc1 -US06825191B2,2,NCCc1cccnc1.O=C(O)CN1C(=O)CN(C(=O)c2ccc(Cl)cc2)Cc2ccccc21>>O=C(CN1C(=O)CN(C(=O)c2ccc(Cl)cc2)Cc2ccccc21)NCCc1cccnc1 -US20100240658A1,3,COC(=O)c1ccc(Br)c(C)c1.COCc1ccccc1B(O)O>>COCc1ccccc1-c1ccc(C(=O)OC)cc1C -US20100152157A1,1,CC(C)N1CCNCC1.Clc1ccc2nc(-c3ccccc3)c(-c3ccnnc3)n2n1>>CC(C)N1CCN(c2ccc3nc(-c4ccccc4)c(-c4ccnnc4)n3n2)CC1 -US20130296327A1,6,Cc1cc2c(cc1-c1cc(N3CCN(C)CC3)nc(N)n1)CN(C(=O)OC(C)(C)C)CC2>>Cc1cc2c(cc1-c1cc(N3CCN(C)CC3)nc(N)n1)CNCC2 -US20060229309A1,2,CCCO[C@@H]1C[C@H]([C@@H](O[Si](C)(C)C(C)(C)C)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cccc(C(=O)O)c2)N(C(=O)OC(C)(C)C)C1.COC[C@H]1CCCN1>>CCCO[C@@H]1C[C@H]([C@@H](O[Si](C)(C)C(C)(C)C)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cccc(C(=O)N3CCC[C@@H]3COC)c2)N(C(=O)OC(C)(C)C)C1 -US20100093991A1,7,C[C@]1(OCc2ccccc2)C(=O)O[C@H](COCc2ccccc2)[C@H]1OCc1ccccc1>>C[C@]1(OCc2ccccc2)C(O)O[C@H](COCc2ccccc2)[C@H]1OCc1ccccc1 -US20060100262A1,6,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCN(CCN(C)Cc1cccnc1)Cc1ccccc1-3>>CN(CCN1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc2C1)Cc1cccnc1 -US20090149445A1,3,Clc1ccc2c(c1)CCc1ccccc1C2=CBr.OB(O)c1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(C=C2c3ccccc3CCc3cc(Cl)ccc32)cc1 -US20150210630A1,9,C[C@H](NC(=O)OC(C)(C)C)C(=O)c1ncc(Cl)cc1Cl.NO>>C[C@H](NC(=O)OC(C)(C)C)C(=NO)c1ncc(Cl)cc1Cl -US07550473B2,6,CC(C)(C)OC(=O)NCC1CCC(CNc2nc(NCc3ccccc3Cl)ncc2C(=O)O)CC1>>NCC1CCC(CNc2nc(NCc3ccccc3Cl)ncc2C(=O)O)CC1 -US20140080801A1,6,CC1(NC(=O)C(F)(F)F)CCN(Cc2ccccc2)CCC1O>>CC1(NC(=O)C(F)(F)F)CCNCCC1O -US08518972B2,1,O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1.c1cncc(C2CCNCC2)c1>>O=C1CCC(N2Cc3c(OCc4ccc(CN5CCC(c6cccnc6)CC5)cc4)cccc3C2=O)C(=O)N1 -US20100168103A1,1,COC(=O)C1CCNCC1.ClCc1ccccc1>>COC(=O)C1CCN(Cc2ccccc2)CC1 -US20120065196A1,1,CCOC(=O)c1c[nH]nc1C(F)(F)F.Fc1cccc(I)c1>>CCOC(=O)c1cn(-c2cccc(F)c2)nc1C(F)(F)F -US07999132B2,6,CC(C)(C)OC(=O)c1ccc(N2CCc3ccccc32)cc1NC(=O)c1ccccc1>>O=C(Nc1cc(N2CCc3ccccc32)ccc1C(=O)O)c1ccccc1 -US20090163709A1,1,CI.Oc1cccc(O)c1O>>COc1c(O)cccc1O -US20100234351A1,6,CC(C)(CS(=O)(=O)CCO)NC(=O)OC(C)(C)C>>CC(C)(N)CS(=O)(=O)CCO -US20100048537A1,1,CN1CCc2sccc2C(O)C1.Fc1ccccc1Br>>CN1CCc2sccc2C(Oc2ccccc2Br)C1 -US20140081017A1,1,COC(=O)Cc1ccc(CCCCc2ccc(O)cc2)cc1.ClCCCN1CCOCC1>>COC(=O)Cc1ccc(CCCCc2ccc(OCCCN3CCOCC3)cc2)cc1 -US08476297B2,4,CC(C)(CNC(=O)c1ccc(C(F)(F)F)cc1)c1ccccc1>>CC1(C)CN=C(c2ccc(C(F)(F)F)cc2)c2ccccc21 -US20150152065A1,1,NCc1ccccc1OC(F)F.O=[N+]([O-])c1ccc(Br)cc1F>>O=[N+]([O-])c1ccc(Br)cc1NCc1ccccc1OC(F)F -US06552069B1,7,O=C(O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>OCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F -US06066720,2,Nc1ncnc2c1nnn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.O=C(Cl)c1ccccc1>>O=C(Nc1ncnc2c1nnn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)c1ccccc1 -US07229987B2,1,CN(C)CCCCl.O=S(=O)(Cc1ccc2ccccc2c1)Cc1nnc(-c2ccc(O)cc2)o1>>CN(C)CCCOc1ccc(-c2nnc(CS(=O)(=O)Cc3ccc4ccccc4c3)o2)cc1 -US07368578B2,6,CCOP(=O)(/C=C\c1cn(-c2ccccc2)nc1OCc1ccc(OCc2nc(-c3cccc(C(=O)OC)c3)oc2C)c(OC)c1)OCC>>CCOP(=O)(/C=C\c1cn(-c2ccccc2)nc1OCc1ccc(OCc2nc(-c3cccc(C(=O)O)c3)oc2C)c(OC)c1)OCC -US20100291003A1,1,COC(=O)c1ccc(C=O)cc1.Nc1ccc(C(=Cc2ccc(F)cc2)C(=O)NC2CC2)cc1>>COC(=O)c1ccc(CNc2ccc(C(=Cc3ccc(F)cc3)C(=O)NC3CC3)cc2)cc1 -US20040186091A1,1,COC(=O)CCN.O=[N+]([O-])c1ccc(Cl)cc1CBr>>COC(=O)CCNCc1cc(Cl)ccc1[N+](=O)[O-] -US08518972B2,1,Clc1ccc(C2CCNCC2)cc1.O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1>>O=C1CCC(N2Cc3c(OCc4ccc(CN5CCC(c6ccc(Cl)cc6)CC5)cc4)cccc3C2=O)C(=O)N1 -US20120108577A1,9,CC(C)(C)OC(=O)N1C[C@@H](N=[N+]=[N-])CC[C@@H]1CCN1C(=O)COc2ccc(C#N)cc21>>CC(C)(C)OC(=O)N1C[C@@H](N)CC[C@@H]1CCN1C(=O)COc2ccc(C#N)cc21 -US06235731B1,5,CCOC(=O)C(F)(F)F.NCCCc1ccccc1>>O=C(NCCCc1ccccc1)C(F)(F)F -US08816090B2,1,COC(=O)C1(CC=O)CCOCC1.c1cc(OCC2CCCC2)c2c(OCC3CCNCC3)noc2c1>>COC(=O)C1(CCN2CCC(COc3noc4cccc(OCC5CCCC5)c34)CC2)CCOCC1 -US20060160794A1,1,C1COCCN1.CC1(C)CC(=O)N(c2ccccc2)N1C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1Cl>>CC1(C)CC(=O)N(c2ccccc2)N1C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCOCC1 -US20090118254A1,1,BrCc1ccccn1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCc2ccccn2)cc1 -US20100184753A1,1,COc1cccc(Br)c1.NC1CC1>>COc1cccc(NC2CC2)c1 -US20110196174A1,1,Nc1ccccc1.O=CC=Cc1ccccc1>>C(=Cc1ccccc1)C=Nc1ccccc1 -US08217069B2,1,COc1cc(Cl)c(N)cc1OCc1c(F)cccc1OC.COc1nc(Cl)nc(Cl)c1[N+](=O)[O-]>>COc1cc(Cl)c(Nc2nc(Cl)nc(OC)c2[N+](=O)[O-])cc1OCc1c(F)cccc1OC -US20100256356A1,1,C=CCBr.Nc1ccc(F)cc1>>C=CCNc1ccc(F)cc1 -US05491244,1,O=C(Cl)c1ccccc1.O=C([O-])c1ccccc1>>O=C(OC(=O)c1ccccc1)c1ccccc1 -US05447957,7,COC(=O)c1ccccc1Oc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)c1ccccc1Oc1ccc(C(F)(F)F)cc1N -US20040259904A1,5,O=C1CCc2cc(Br)ccc21.OCCO>>Brc1ccc2c(c1)CCC21OCCO1 -US07745641B2,1,CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(C=O)ccc21.NCC1CCCCC1>>CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(CNCC3CCCCC3)ccc21 -US08956999B2,1,CC1(C)C(=O)C=C(Cl)C(C)(C)C1=O.OCc1ccc(Br)s1>>CC1(C)C(=O)C=C(OCc2ccc(Br)s2)C(C)(C)C1=O -US20140142085A1,1,CCOC(=O)CBr.FC(F)(F)c1n[nH]c2c1CC1(CC2)OCCO1>>CCOC(=O)Cn1nc(C(F)(F)F)c2c1CCC1(C2)OCCO1 -US04054572,9,[N-]=[N+]=NC1CCN2c3ccccc3Cc3ccccc3C2C1>>NC1CCN2c3ccccc3Cc3ccccc3C2C1 -US06492416B1,3,CC(=O)c1cccc(B(O)O)c1.CC1(C)OC(c2ccc(S(C)(=O)=O)cc2)=C(Br)C1=O>>CC(=O)c1cccc(C2=C(c3ccc(S(C)(=O)=O)cc3)OC(C)(C)C2=O)c1 -US08198456B2,7,COC(=O)c1ccc2[nH]ncc2n1>>OCc1ccc2[nH]ncc2n1 -US20050148624A1,3,COC(=O)c1c(OS(=O)(=O)C(F)(F)F)c2cc(Cl)ccc2c(=O)n1Cc1ccc(S(C)(=O)=O)cc1.O=Cc1cccc(B(O)O)c1>>COC(=O)c1c(-c2cccc(C=O)c2)c2cc(Cl)ccc2c(=O)n1Cc1ccc(S(C)(=O)=O)cc1 -US07015218B1,2,Cc1c(C(=O)Cl)cnn1-c1ccc(Cl)cc1.Nc1ccc(N2CCC(N3CCOCC3)CC2)c(C(F)(F)F)c1>>Cc1c(C(=O)Nc2ccc(N3CCC(N4CCOCC4)CC3)c(C(F)(F)F)c2)cnn1-c1ccc(Cl)cc1 -US09120788B2,2,C1CNC1.CCOC(=O)c1nc2cccnc2n1-c1ccc(C#N)c(F)c1>>N#Cc1ccc(-n2c(C(=O)N3CCC3)nc3cccnc32)cc1F -US20080312226A1,1,Clc1nc(-c2cccs2)ns1.O=C(Nc1noc2ccccc12)N1CCNCC1>>O=C(Nc1noc2ccccc12)N1CCN(c2nc(-c3cccs3)ns2)CC1 -US08013008B2,3,CCC[Mg+].C[C@H]1C(=O)CCN1C(=O)OCc1ccccc1>>CCC[C@]1(O)CCN(C(=O)OCc2ccccc2)[C@H]1C -US05527795,6,C=CCC(CNC(=O)OC(C)(C)C)C(=O)OC>>C=CCC(CN)C(=O)OC -US05506356,6,CCCC[C@H](N)C(=O)OC(C)(C)C>>CCCC[C@H](N)C(=O)O -US07790728B2,3,O=C(Nc1cnc(-c2ccncc2)c(Cl)n1)C1CC1.[Zn+]c1ncco1>>O=C(Nc1cnc(-c2ccncc2)c(-c2ncco2)n1)C1CC1 -US20070270588A1,3,C=O.CCC(CC)n1ccc2c(C)nc(N(CC)c3c(C)cc(C)cc3C)nc21.CNC>>CCC(CC)n1cc(CN(C)C)c2c(C)nc(N(CC)c3c(C)cc(C)cc3C)nc21 -US20020193599A1,6,COCCCCC(=O)OC>>COCCCCC(=O)O -US20090054405A1,1,N#CCCl.Oc1cc(Br)cnc1Cl>>N#CCOc1cc(Br)cnc1Cl -US20080280875A1,2,CC1(C)Cc2c(Oc3cc(F)cc(F)c3)cc(C(=O)O)cc2O1.Cn1ccc(N)n1>>Cn1ccc(NC(=O)c2cc(Oc3cc(F)cc(F)c3)c3c(c2)OC(C)(C)C3)n1 -US07074801B1,1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1cc(Br)ccc1F>>CC(C)(C)OC(=O)N1CCN(c2ccc(F)c(C#N)c2)CC1 -US20020038055A1,9,O=C(Cl)c1cccc(F)c1>>O=Cc1cccc(F)c1 -US08273745B2,6,O=C1c2ccccc2C(=O)N1CCn1cc(C(c2ccccc2)c2ccccc2)ccc1=O>>NCCn1cc(C(c2ccccc2)c2ccccc2)ccc1=O -US06953850B1,2,COc1ccc(CO[C@H]2[C@H](O)[C@@H](COC(C)(C)C)O[C@](SC)([SiH](c3ccccc3)c3ccccc3)[C@@H]2N=[N+]=[N-])cc1.O=C(Cl)c1ccccc1-c1ccccc1>>COc1ccc(CO[C@H]2[C@H](OC(=O)c3ccccc3-c3ccccc3)[C@@H](COC(C)(C)C)O[C@](SC)([SiH](c3ccccc3)c3ccccc3)[C@@H]2N=[N+]=[N-])cc1 -US03971803,3,C=O.CC(C)(C)c1cccc(C(C)(C)C)c1O.S=c1[nH]nc(-c2ccccc2)o1>>CC(C)(C)c1cc(Cn2nc(-c3ccccc3)oc2=S)cc(C(C)(C)C)c1O -US06242448B1,1,COc1ccccc1N1CCNCC1.ClCc1oc(CC2CCCCC2)nc1Cc1ccccc1>>COc1ccccc1N1CCN(Cc2oc(CC3CCCCC3)nc2Cc2ccccc2)CC1 -US20140288045A1,2,CC(C)(C)OC(=O)N1CC(N2CCNCC2)C1.COc1cc(Cl)c(I)cc1NCC(=O)O>>COc1cc(Cl)c(I)cc1NCC(=O)N1CCN(C2CN(C(=O)OC(C)(C)C)C2)CC1 -US05801168,6,CCOC(=O)C=Cc1c(OC)c(=O)[nH]c2cc(Cl)ccc2c1=O>>CCOC(=O)/C=C/c1c(O)c(=O)[nH]c2cc(Cl)ccc2c1=O -US20110034469A1,6,CCO[C@@H]1C[C@@H]2CN(C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)c3ccc(F)cc3)[C@H](C(=O)N[C@@H]3CCOc4ccccc43)CN2C1>>CCO[C@@H]1C[C@@H]2CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)c3ccc(F)cc3)[C@H](C(=O)N[C@@H]3CCOc4ccccc43)CN2C1 -US20090286768A1,2,Nc1cc(Cl)ccc1Oc1ccccc1.O=CO>>O=CNc1cc(Cl)ccc1Oc1ccccc1 -US20040229900A1,6,CCNC(=O)N1CC2CC(CN(CC(COc3ccc(C#N)cc3)NC(=O)OC(C)(C)C)C2)C1>>CCNC(=O)N1CC2CC(CN(CC(N)COc3ccc(C#N)cc3)C2)C1 -US20070105865A1,1,CC1(C)CNc2ccc([N+](=O)[O-])cc21.CI>>CN1CC(C)(C)c2cc([N+](=O)[O-])ccc21 -US20150164876A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(OCc1ccccc1)c1cccc(C#CCOCCOCCOCCOCCO)c1>>Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCC#Cc2cccc(C(=O)OCc3ccccc3)c2)cc1 -US08513424B2,1,CCCc1cnc(N2CCC(OS(C)(=O)=O)CC2)nc1.O=c1cc(O)c(-c2ccccc2)c[nH]1>>CCCc1cnc(N2CCC(Oc3cc(=O)[nH]cc3-c3ccccc3)CC2)nc1 -US20150164872A1,1,CNC.CS(=O)(=O)OCCc1cnn(-c2cc(C#N)ccn2)c1OCc1ccc(F)cc1>>CN(C)CCc1cnn(-c2cc(C#N)ccn2)c1OCc1ccc(F)cc1 -US20040220191A1,6,CN(C(=O)OC(C)(C)C)[C@@H]1CCN(c2ccc([N+](=O)[O-])cc2)C1>>CN[C@@H]1CCN(c2ccc([N+](=O)[O-])cc2)C1 -US20110136792A1,3,COC(=O)c1ccc(F)c(COc2ccc(I)cc2)c1.OB(O)c1ccc(F)cc1F>>COC(=O)c1ccc(F)c(COc2ccc(-c3ccc(F)cc3F)cc2)c1 -US20140275152A1,1,CC(=O)N1CCC(c2ccccc2)=C(CCl)C1.O=Cc1c(O)cccc1O>>CC(=O)N1CCC(c2ccccc2)=C(COc2cccc(O)c2C=O)C1 -US04448728,6,CCOC(=O)C1C(C)(C)C1(C#N)C(=O)OCC>>CCOC(=O)C1C(C)(C)C1(C#N)C(=O)O -US07855292B2,2,Nc1cc(I)ccc1C(=O)O.O=S(=O)(Cl)c1c(F)cccc1F>>O=C(O)c1ccc(I)cc1NS(=O)(=O)c1c(F)cccc1F -US04362895,3,COc1ccc(C(=O)Cl)cc1.Oc1cccc(O)c1>>COc1ccc(C(=O)c2ccc(O)cc2O)cc1 -US08592629B2,3,CC(C)(C)Oc1ncc(B2OC(C)(C)C(C)(C)O2)cc1Cl.CS(=O)(=O)NC(=O)c1cc(F)c(CBr)cc1F>>CC(C)(C)Oc1ncc(Cc2cc(F)c(C(=O)NS(C)(=O)=O)cc2F)cc1Cl -US20040157894A1,1,CC(C)(C)C(=O)OCCl.O=C1CC(S)CN1Cc1ccc(Oc2ccccc2)cc1>>CC(C)(C)C(=O)OCSC1CC(=O)N(Cc2ccc(Oc3ccccc3)cc2)C1 -US05726205,1,CN(C)Cc1ccc([C@@H]2CC[C@@H](O)CC2)cc1.Cc1cc(C(=O)O)ccc1Cl>>Cc1cc(C(=O)O[C@@H]2CC[C@@H](c3ccc(CN(C)C)cc3)CC2)ccc1Cl -US07935721B2,3,O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C12COc1ccc(Br)cc12.OB(O)c1cccnc1>>O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C12COc1ccc(-c3cccnc3)cc12 -US05143920,1,CCCC(=O)c1cnc2c(C(C)=O)cccc2c1Cl.Cc1cc(O)ccc1N>>CCCC(=O)c1cnc2c(C(C)=O)cccc2c1Nc1ccc(O)cc1C -US08809525B2,1,Nc1cccc(O)c1.Nc1nnc(Br)c(-c2ccccc2)n1>>Nc1cccc(Oc2nnc(N)nc2-c2ccccc2)c1 -US08546427B2,2,CC1(C)CC(c2cccc(N)c2)Nc2ccc(C#N)cc21.CS(=O)(=O)Cl>>CC1(C)CC(c2cccc(NS(C)(=O)=O)c2)Nc2ccc(C#N)cc21 -US08785436B2,7,CCOC(=O)C(F)(F)[C@](C)(N[S@](=O)C(C)(C)C)[C@H]1C[C@@H]1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@H]1C[C@@H]1[C@@](C)(N[S@](=O)C(C)(C)C)C(F)(F)CO -US08263607B2,9,Cc1ccc(Br)c2c1C(C(C)C)N(C(=O)CNCC1(O)CCCCC1)CC2>>Cc1cccc2c1C(C(C)C)N(C(=O)CNCC1(O)CCCCC1)CC2 -US05102890,1,CN(C)CCC(=O)O.O=C1c2ccccc2C(Cl)N1c1ccc2ccc(Cl)nc2n1>>CN(C)CCC(=O)OC1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1 -US20100035865A1,6,CCOC(=O)[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1>>O=C(O)[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1 -US04145549,6,CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccccc1 -US20020010333A1,1,CC(=O)CCl.Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1>>CC(=O)Cn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O -US05610144,1,C=C(C)C.O=C(O)[C@@H]1CSC(c2ccccc2)N1>>CC(C)(C)OC(=O)[C@@H]1CSC(c2ccccc2)N1 -US06476030B1,3,Cn1ncnc1COc1nn2c(-c3ccccc3F)nncc2c1Br.OB(O)c1cccc(C(F)(F)F)c1>>Cn1ncnc1COc1nn2c(-c3ccccc3F)nncc2c1-c1cccc(C(F)(F)F)c1 -US20100056516A1,1,COC(=O)c1cc(Br)cnc1Cl.NOCc1ccccc1>>COC(=O)c1cc(Br)cnc1NOCc1ccccc1 -US05929120,2,CC(C)(C)OC(=O)NCCN.COC(=O)c1cccc(C(=O)O)c1>>COC(=O)c1cccc(C(=O)NCCNC(=O)OC(C)(C)C)c1 -US20140206660A1,9,COC1CCN(C(=O)OC(C)(C)C)CC1CN=[N+]=[N-]>>COC1CCN(C(=O)OC(C)(C)C)CC1CN -US20100278833A1,2,CS(=O)(=O)Cl.C[C@@H](Oc1cc(-n2cnc3cnc(CO)cc32)sc1C(N)=O)c1ccccc1Cl>>C[C@@H](Oc1cc(-n2cnc3cnc(COS(C)(=O)=O)cc32)sc1C(N)=O)c1ccccc1Cl -US06838463B2,1,C#CCOc1cc(Cl)ncn1.Oc1cccc(F)c1>>C#CCOc1cc(Oc2cccc(F)c2)ncn1 -US20060217561A1,2,CC(C)O.COc1ccc(C2=N[C@H](C(=O)O)CS2)c(OC)c1>>COc1ccc(C2=N[C@H](C(=O)OC(C)C)CS2)c(OC)c1 -US05326900,3,CC1(C)CCC(C)(C)c2cc(C(=O)Cl)ccc21.COC(=O)c1ccc(CBr)cc1>>COC(=O)c1ccc(CC(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 -US04479942,6,COc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccc(OC)cc2)C(=O)N[C@@H]2[C@@H](C(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O)cc1>>COc1ccc(C[C@H](N)C(=O)N[C@@H](Cc2ccc(OC)cc2)C(=O)N[C@@H]2[C@@H](C(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O)cc1 -US08673891B2,2,CNC.C[C@H](Nc1cc(C(=O)O)cc(Nc2cnccn2)n1)c1ccc(F)cc1>>C[C@H](Nc1cc(C(=O)N(C)C)cc(Nc2cnccn2)n1)c1ccc(F)cc1 -US08497269B2,1,Cc1cc(F)ccc1-c1nncc2cc(Cl)ccc12.Fc1cccc(S)c1>>Cc1cc(F)ccc1-c1nncc2cc(Sc3cccc(F)c3)ccc12 -US20130196872A1,7,CCC(=O)CC(=O)OC>>CCC(O)CC(=O)OC -US20130331372A1,3,COC(=O)c1cnc(Cl)cc1C(F)(F)F.COc1ccc(B(O)O)c(F)c1>>COC(=O)c1cnc(-c2ccc(OC)cc2F)cc1C(F)(F)F -US06331637B1,2,Cc1noc(N)c1C.O=S(=O)(Cl)c1cc2ccccc2s1>>Cc1noc(NS(=O)(=O)c2cc3ccccc3s2)c1C -US20130252882A1,3,CC1(C)OB(c2cnc3[nH]ccc3c2)OC1(C)C.COC(=O)c1cc(C2CC2)c2c(C)c(Cl)ccn2c1=O>>COC(=O)c1cc(C2CC2)c2c(C)c(-c3cnc4[nH]ccc4c3)ccn2c1=O -US20120010223A1,4,CSC(=S)c1c(N)n(C)c(=O)n(C)c1=O>>CSc1snc2c1c(=O)n(C)c(=O)n2C -US20140163025A1,6,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(OC6CCOCC6)cc5F)ccc(F)c43)ccc21>>O=C(O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(OC6CCOCC6)cc5F)ccc(F)c43)ccc21 -US20140296260A1,1,CC[C@H](N)c1nc2cccc(F)c2c(=O)n1-c1cccc(CC(F)(F)F)c1.Clc1ccnc2[nH]cnc12>>CC[C@H](Nc1ccnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1cccc(CC(F)(F)F)c1 -US05238832,1,C#CCO.C1=COCCC1>>C#CCOC1CCCCO1 -US07425554B2,3,CC1(C)C=C(B2OC(C)(C)C(C)(C)O2)CC(C)(C)C1.COC1CCN(c2ccc([N+](=O)[O-])c(OS(=O)(=O)C(F)(F)F)c2)CC1>>COC1CCN(c2ccc([N+](=O)[O-])c(C3=CC(C)(C)CC(C)(C)C3)c2)CC1 -US20150210682A1,1,COCCOc1cc(CC(=O)C(C)C)ccc1F.[NH4+]>>COCCOc1cc(CC(N)C(C)C)ccc1F -US20110183989A1,6,CC(C)(C)OC(=O)N1CCN2C(=O)N([C@@H]3C[C@H]3c3ccccc3)C(=O)C2C1>>O=C1C2CNCCN2C(=O)N1[C@@H]1C[C@H]1c1ccccc1 -US04999378,1,COC(=O)C(C)=Cc1ccc(OCCCCl)cc1.Nc1ccc(Cl)cc1>>COC(=O)C(C)=Cc1ccc(OCCCNc2ccc(Cl)cc2)cc1 -US20090042896A1,6,CC(C)(C)[Si](C)(C)OC[C@H](Oc1ccc(Cl)cn1)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)c(Cl)c1>>CC(C)(C)[Si](C)(C)OC[C@H](Oc1ccc(Cl)cn1)[C@H]1CNC[C@@H]1c1ccc(Cl)c(Cl)c1 -US06825200B1,1,Brc1ccccc1.C[C@H]1CNCCN1>>C[C@H]1CN(c2ccccc2)CCN1 -US20140200227A1,2,CC(=O)OC1CCc2c1ncc(N)c2N1C[C@H](C)C[C@H](NC(=O)OC(C)(C)C)C1.O=C(O)c1ccc(F)c(-c2c(F)cc(OC3CCCOC3)cc2F)n1>>CC(=O)OC1CCc2c1ncc(NC(=O)c1ccc(F)c(-c3c(F)cc(OC4CCCOC4)cc3F)n1)c2N1C[C@H](C)C[C@H](NC(=O)OC(C)(C)C)C1 -US04168385,1,COC(=O)C(Br)c1ccc(Oc2ccc(C#N)cc2)cc1.Oc1ccc(Cl)cc1>>COC(=O)C(Oc1ccc(Cl)cc1)c1ccc(Oc2ccc(C#N)cc2)cc1 -US06613772B1,2,COC(=O)c1cc(OC)c(OC)c(OC)c1N.O=C(Cl)c1ccc(Cl)cc1>>COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c1ccc(Cl)cc1 -US20080051418A1,1,COC(=O)c1cc(O)n[nH]1.ClCc1ccc2ccccc2n1>>COC(=O)c1cc(OCc2ccc3ccccc3n2)n[nH]1 -US20150111870A1,2,COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1C(=O)O.NC1CC1>>COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1C(=O)NC1CC1 -US06586441B2,3,C=C[Sn](CCCC)(CCCC)CCCC.N#Cc1c(OS(=O)(=O)C(F)(F)F)nc(N)nc1-c1ccco1>>C=Cc1nc(N)nc(-c2ccco2)c1C#N -US07709481B2,3,Cc1nc(Br)sc1COc1ccc(-c2nc(=O)o[nH]2)c(Cl)c1.OB(O)c1cc2ccccc2s1>>Cc1nc(-c2cc3ccccc3s2)sc1COc1ccc(-c2nc(=O)o[nH]2)c(Cl)c1 -US04489089,2,NCCCCCCCCn1ccnc1.O=C(Cl)c1ccc(Cl)s1>>O=C(NCCCCCCCCn1ccnc1)c1ccc(Cl)s1 -US20080103123A1,2,CC(C)(C)OC(=O)N1CCC(COc2ccc(-c3ccc(C(=O)O)cc3)nc2)CC1.COCCN>>COCCNC(=O)c1ccc(-c2ccc(OCC3CCN(C(=O)OC(C)(C)C)CC3)cn2)cc1 -US07605157B2,2,CC(Br)C(=O)Cl.OC(CNCc1ccccc1)C(F)(F)F>>CC(Br)C(=O)N(Cc1ccccc1)CC(O)C(F)(F)F -US20150150845A1,6,COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O>>CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 -US08501758B2,1,CC(C)NN.O=Cc1ccccc1>>CC(C)NN=Cc1ccccc1 -US07880042B2,1,COc1c(F)cccc1[C@H](C)C[C@@](O)(C=O)C(F)(F)F.Cc1ncc2c(N)ccc(F)c2n1>>COc1c(F)cccc1[C@H](C)C[C@@](O)(C=Nc1ccc(F)c2nc(C)ncc12)C(F)(F)F -US04997847,6,O=C(O)CCC/C=C\CN1C(=O)c2ccccc2C1=O>>NC/C=C\CCCC(=O)O -US20150031689A1,2,CC(=O)OC(C)=O.NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1>>CC(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 -US07932259B2,1,CCOC(=O)C1CCNCC1.Cc1nc(Cl)c2c(n1)N(c1c(C)cc(Br)cc1C)C(=O)C2C>>CCOC(=O)C1CCN(c2nc(C)nc3c2C(C)C(=O)N3c2c(C)cc(Br)cc2C)CC1 -US08263629B2,7,CCOC(=O)/C(C)=C/[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)OC(C)(C)C>>CCOC(=O)[C@@H](C)CC(Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)OC(C)(C)C -US07105544B2,2,CC(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.CC(C(=O)O)(c1ccccc1)c1ccccc1>>CC(=O)Nc1cccc(C2CCN(CCCNC(=O)C(C)(c3ccccc3)c3ccccc3)CC2)c1 -US06887889B2,2,CC(C)(C)OC(=O)N1CCC(CN)(c2ccc(I)cc2)CC1.O=C(Cl)Cc1cc(F)cc(F)c1>>CC(C)(C)OC(=O)N1CCC(CNC(=O)Cc2cc(F)cc(F)c2)(c2ccc(I)cc2)CC1 -US20130158075A1,2,CCOC(=O)CC1CCC(c2ncc(-c3ccc(N)cc3)s2)CC1.O=C=Nc1cc(F)cc(F)c1>>CCOC(=O)CC1CCC(c2ncc(-c3ccc(NC(=O)Nc4cc(F)cc(F)c4)cc3)s2)CC1 -US20090192138A1,1,C1CNCCN1.CC#CCn1c(Br)c(C#N)c2ncn(CC(=O)c3cccc(OC)c3)c(=O)c21>>CC#CCn1c(N2CCNCC2)c(C#N)c2ncn(CC(=O)c3cccc(OC)c3)c(=O)c21 -US20120202996A1,2,CC(=O)Cl.CC1=CC(C)(C)Nc2ccc(NC(=O)OC(C)(C)C)cc21>>CC(=O)N1c2ccc(NC(=O)OC(C)(C)C)cc2C(C)=CC1(C)C -US08354444B2,8,CC(C)(CCO)c1ccccc1>>CC(C)(CC=O)c1ccccc1 -US08551999B2,6,COC(=O)c1cc2cc(Oc3ccc(NC(=O)c4ccc(Cl)c(Cl)c4)cn3)ccc2[nH]1>>O=C(Nc1ccc(Oc2ccc3[nH]c(C(=O)O)cc3c2)nc1)c1ccc(Cl)c(Cl)c1 -US20030055064A1,1,CC(=O)NC(C)(C)c1ccc(CCl)cc1.c1cnc(N2CCNCC2)nc1>>CC(=O)NC(C)(C)c1ccc(CN2CCN(c3ncccn3)CC2)cc1 -US20030207915A1,7,COc1ccc2ccc(=O)oc2c1>>COc1ccc2c(c1)OC(=O)CC2 -US20050254319A1,1,BrCCCBr.C=C(C)C(=O)O>>C=C(C)C(=O)OCCCBr -US05240923,1,CCN.CN1CC(O)c2cc(S(N)(=O)=O)sc2S1(=O)=O>>CCNC1CN(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 -US20150225379A1,6,COC(=O)c1cccc(CC2(CN(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)CCN(C(=O)OC(C)(C)C)CC2)c1>>COC(=O)c1cccc(CC2(CN(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)CCNCC2)c1 -US20020173655A1,8,CCCCc1nc2c(N)nc3ccccc3c2n1CCCCCSC.O=C(OO)c1cccc(Cl)c1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCCCS(C)=O -US20050197386A1,6,CCCCCC[C@@H]1C(=O)O[C@H]1CCCCCOCc1ccccc1>>CCCCCC[C@@H]1C(=O)O[C@H]1CCCCCO -US20080255136A1,6,N#Cc1cccc(N2CC(c3ccc(OCc4ccccc4)c(OC4CCCC4)c3)CC2=O)c1>>N#Cc1cccc(N2CC(c3ccc(O)c(OC4CCCC4)c3)CC2=O)c1 -US20150133451A1,1,CN1CCNC1=O.Cn1ccc(I)n1>>CN1CCN(c2ccn(C)n2)C1=O -US05206240,1,CS(=O)(=O)Nc1ccc(CCOS(C)(=O)=O)cc1.O=C1CC2(CCCNC2)Oc2ccccc21>>CS(=O)(=O)Nc1ccc(CCN2CCCC3(CC(=O)c4ccccc4O3)C2)cc1 -US05017724,1,CN.Cc1cc(C)c2c(c1O)C(=O)C1CCCCC21>>CNC1c2c(O)c(C)cc(C)c2C2CCCCC21 -US04153719,10,Cc1ccc(C=Cc2ccccc2)cc1.O=C1CCC(=O)N1Br>>BrCc1ccc(C=Cc2ccccc2)cc1 -US06894041B2,7,CC(=O)[C@@H]1CC[C@@H](CNC(=O)OCc2ccccc2)CC1>>CC(O)[C@@H]1CC[C@@H](CNC(=O)OCc2ccccc2)CC1 -US20150152108A1,2,CCc1cnc(N)cn1.O=C(Cl)Oc1ccccc1>>CCc1cnc(NC(=O)Oc2ccccc2)cn1 -US20050171132A1,1,Nc1nc(N)c(-c2ccc(NC(=O)C3CC3)cc2)c(CBr)n1.OCCc1ccccc1>>Nc1nc(N)c(-c2ccc(NC(=O)C3CC3)cc2)c(COCCc2ccccc2)n1 -US20100298384A1,2,COC(=O)Cl.NCC1CN(c2ccc(-n3cnc(Cn4ccnc4)c3)c(F)c2)C(=O)O1>>COC(=O)NCC1CN(c2ccc(-n3cnc(Cn4ccnc4)c3)c(F)c2)C(=O)O1 -US20070249670A1,2,COC(=O)[C@H](CCCC(F)(F)F)NC(=O)c1cc2ccccc2cc1N.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@H](CCCC(F)(F)F)NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C -US20150057271A1,1,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCC(C)N3)cc1.N#Cc1cc(C(F)(F)F)ccc1F>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCC(C)N3c2ccc(C(F)(F)F)cc2C#N)cc1 -US04001426,1,ClCC1CO1.O=C(c1ccccc1)c1c(-c2ccc(O)cc2)oc2ccccc12>>O=C(c1ccccc1)c1c(-c2ccc(OCC3CO3)cc2)oc2ccccc12 -US05760058,7,COC(=O)c1ccc(C(=O)N2CCC(N(C)CCc3ccccc3)CC2)cn1>>CN(CCc1ccccc1)C1CCN(C(=O)c2ccc(CO)nc2)CC1 -US05622937,3,COC(=O)c1cccc(Br)c1.COc1ccccc1B(O)O>>COC(=O)c1cccc(-c2ccccc2OC)c1 -US20140294946A1,1,Clc1nc(N2CCOCC2)c2sc(CN3CCNCC3)cc2n1.O=Cc1ncc[nH]1>>Clc1nc(N2CCOCC2)c2sc(CN3CCN(Cc4ncc[nH]4)CC3)cc2n1 -US04663325,1,COc1ccc(C=O)c(OC)c1.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>COc1ccc(CN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(OC)c1 -US20140288040A1,7,CC(C)(C)[S@@](=O)N[C@@H](CC(=O)O)c1ccc(Cl)c(Oc2ccccc2)c1F>>CC(C)(C)[S@@](=O)N[C@@H](CCO)c1ccc(Cl)c(Oc2ccccc2)c1F -US05273975,6,CCOC(=O)C1(NC(=O)CC)Cc2cccc3c2N(CCC3)C1=O>>CCC(=O)NC1(C(=O)O)Cc2cccc3c2N(CCC3)C1=O -US06107329,2,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.CN>>CNC(=O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C -US20050267095A1,6,COc1cccc(C2(CN(C)C)CCOCC2)c1>>CN(C)CC1(c2cccc(O)c2)CCOCC1 -US20140155419A1,1,COC(=O)Cc1ccc(O)cc1.ClCc1cccnc1>>COC(=O)Cc1ccc(OCc2cccnc2)cc1 -US08299085B2,7,COC(=O)c1cc(N2CCSCC2)c(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)c1cc(N2CCSCC2)c(C(F)(F)F)cc1N -US04254260,2,CCOC(=O)Cc1csc(N)n1.CS(=O)(=O)Cl>>CCOC(=O)Cc1csc(NS(C)(=O)=O)n1 -US20110053912A1,1,O=C(c1cnc(Cl)nc1C(F)(F)F)N1CCS(=O)(=O)CC1.OC1CN2CCC1CC2>>O=C(c1cnc(OC2CN3CCC2CC3)nc1C(F)(F)F)N1CCS(=O)(=O)CC1 -US20100099657A2,6,CCOC(=O)CSCC1(c2ccc(C)cc2)OCC(C)(C)CO1>>Cc1ccc(C2(CSCC(=O)O)OCC(C)(C)CO2)cc1 -US20100137372A1,2,Cc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1N.O=C(O)c1cccc(Br)c1>>Cc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1NC(=O)c1cccc(Br)c1 -US09102665B2,8,COC(=O)c1ccccc1SCC(O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1>>COC(=O)c1ccccc1SCC(=O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1 -US05994368,9,CCOC(=O)c1nc2ccc(C)cc2c(Cl)c1C>>CCOC(=O)c1nc2ccc(C)cc2cc1C -US20090318435A1,1,CC(=O)[O-].CCCn1nc2c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc3ccccc3c2c1CCCCCl>>CCCn1nc2c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc3ccccc3c2c1CCCCOC(C)=O -US20110263591A1,2,COCCCN.O=C(O)c1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1>>COCCCNC(=O)c1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1 -US20050038031A1,7,CCOC(=O)c1ccnc(C(=O)NC)c1>>CNC(=O)c1cc(CO)ccn1 -US20110105509A1,7,Cc1c(-c2ccc(=O)n(Cc3cccc(F)c3F)c2)c2cc(F)ccc2n1CC(=O)O>>Cc1c(-c2ccc(=O)n(Cc3cccc(F)c3F)c2)c2cc(F)ccc2n1CCO -US08716470B2,3,CC1(C)OB(c2ccc(N3CCOCC3)cc2)OC1(C)C.OCc1cccc(Br)c1>>OCc1cccc(-c2ccc(N3CCOCC3)cc2)c1 -US08765730B2,9,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(CCC(=O)O)c1)c1ccc(S(C)(=O)=O)cc1.NO>>Cc1cc(Cl)ccc1C(C/C(=N\O)c1ccc(=O)n(CCC(=O)O)c1)c1ccc(S(C)(=O)=O)cc1 -US06964965B2,1,CCc1cnc(CC)c(Cl)n1.N[C@@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1O>>CCc1cnc(CC)c(N[C@@H]2CN(C(=O)OCc3ccccc3)C[C@@H]2O)n1 -US04818765,2,CC(C)O.O=C(O)Cc1ccc(F)cc1>>CC(C)OC(=O)Cc1ccc(F)cc1 -US07897618B2,2,Cn1cc(-c2ccc(F)cc2)c(C(=O)O)n1.c1ccc2sc(CC3CCCCN3)nc2c1>>Cn1cc(-c2ccc(F)cc2)c(C(=O)N2CCCCC2Cc2nc3ccccc3s2)n1 -US20050009841A1,2,Nc1ccc(Cl)cc1.O=C(O)C1=CCN(c2ncccn2)CC1>>O=C(Nc1ccc(Cl)cc1)C1=CCN(c2ncccn2)CC1 -US20090186870A1,9,N.O=C(O)c1cc(-c2ccccn2)ccc1Cl>>NC(=O)c1cc(-c2ccccn2)ccc1Cl -US20070265289A1,1,CC(C)(C)OC(=O)N1CCCC(c2cc(-c3c(O)cccc3O)nc(N)n2)C1.CCI>>CCOc1cccc(O)c1-c1cc(C2CCCN(C(=O)OC(C)(C)C)C2)nc(N)n1 -US06271234B1,6,COC(CN(C(=O)C1CCCCC1)c1ccccn1)OC>>O=CCN(C(=O)C1CCCCC1)c1ccccn1 -US20030191118A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COC(=O)[C@H](Cc1ccc(-c2ccccc2C=O)cc1)NC(=O)c1c(Cl)cccc1Cl>>COC(=O)C=Cc1ccccc1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)OC)cc1 -US20150141477A1,2,Cc1c(COC(C)(C)C(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C(F)(F)F)cc1.NCc1ccc(C(=O)O)cc1>>Cc1c(COC(C)(C)C(=O)NCc2ccc(C(=O)O)cc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C(F)(F)F)cc1 -US20080312234A1,1,CS(=O)(=O)Nc1ccc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2Cl)cc1F.OC1CCNC1>>CS(=O)(=O)Nc1ccc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2N2CCC(O)C2)cc1F -US20100087427A1,2,C1CCNCC1.O=C(Cl)CCl>>O=C(CCl)N1CCCCC1 -US20090270361A1,3,C[Mg+].Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Cc1ccc(C(=O)N2CCC(=O)CC2)cc1>>Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Cc1ccc(C(=O)N2CCC(C)(O)CC2)cc1 -US20070254882A1,6,CCOC(=O)CN(Cc1ccc(OCc2nc(-c3cccs3)oc2C)cc1)S(=O)(=O)N(C)C>>Cc1oc(-c2cccs2)nc1COc1ccc(CN(CC(=O)O)S(=O)(=O)N(C)C)cc1 -US20140228565A1,2,COC(=O)c1scc(-c2ccccc2)c1N.COc1ccc(N)cc1>>COc1ccc(NC(=O)c2scc(-c3ccccc3)c2N)cc1 -US08232273B2,1,CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)ccc1CCCI.Oc1ccnc(Cl)c1>>CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)ccc1CCCOc1ccnc(Cl)c1 -US07649093B2,6,CCCc1cc2cc(OC)c(F)cc2c(OCOC)c1-c1ccccc1>>CCCc1cc2cc(OC)c(F)cc2c(O)c1-c1ccccc1 -US07098212B2,6,COC(=O)COc1cc(C)ccc1CCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C>>Cc1ccc(CCC(=O)N2C[C@H](C)N(Cc3ccc(F)cc3)C[C@H]2C)c(OCC(=O)O)c1 -US20080015223A1,3,Cn1ncc(Br)c1NC(=O)c1cccc(I)c1.OB(O)c1ccc(F)cc1>>Cn1ncc(Br)c1NC(=O)c1cccc(-c2ccc(F)cc2)c1 -US20150175530A1,6,COC(=O)[C@@H](NC(=O)c1ccc(C#C/C=C/CC(O)CO)cc1)C(C)(C)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](NC(=O)c1ccc(C#C/C=C/CC(O)CO)cc1)C(C)(C)N -US20090192162A1,3,C#Cc1ccccc1.CCOC(=O)COc1ccc(SCc2cc(Br)cc(OCC(C)C)c2)cc1C>>CCOC(=O)COc1ccc(SCc2cc(C#Cc3ccccc3)cc(OCC(C)C)c2)cc1C -US20050043354A1,2,Cc1cc(F)ccc1C1C2CNCC2CN1C(=O)N(C)C(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)CN1CCCC1>>Cc1cc(F)ccc1C1C2CN(C(=O)CN3CCCC3)CC2CN1C(=O)N(C)C(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US04940710,1,O=C(O)c1cn(C2CC2)c2cc(Cl)c(F)cc2c1=O.c1cc(C2CNCCN2)n[nH]1>>O=C(O)c1cn(C2CC2)c2cc(N3CCNC(c4cc[nH]n4)C3)c(F)cc2c1=O -US06521627B1,7,CC(=O)OC(C)c1ncnc(Cl)c1I>>CC(O)c1ncnc(Cl)c1I -US20020045747A1,2,C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O.NC1C(=O)NCc2cc(-c3ccccc3)ccc21>>C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)NCc2cc(-c3ccccc3)ccc21 -USRE030241,2,C=CCC=CC(=O)Cl.CC(C)NCC(=O)c1ccc(OC(=O)C2CC(C)(C)C2)c(O)c1>>C=CCC=CC(=O)Oc1cc(C(=O)CNC(C)C)ccc1OC(=O)C1CC(C)(C)C1 -US08791102B2,2,O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccccc2)CN1.O=C(O)CCC(=O)c1cccs1>>O=C(CCC(=O)N1C[C@H](Cc2ccccc2)C[C@H]1C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1)c1cccs1 -US20150080412A1,2,CCn1c(CCCc2ccc(-c3ccc(N)cn3)cc2)nn(Cc2ccc(C(C)(C)C)cc2)c1=O.CS(=O)(=O)Cl>>CCn1c(CCCc2ccc(-c3ccc(NS(C)(=O)=O)cn3)cc2)nn(Cc2ccc(C(C)(C)C)cc2)c1=O -US20080275085A1,2,Cc1cc(F)ccc1[C@H]1CNCC[C@@H]1C(=O)N(C)[C@@H](C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=S(=O)(Cl)C1CC1>>Cc1cc(F)ccc1[C@H]1CN(S(=O)(=O)C2CC2)CC[C@@H]1C(=O)N(C)[C@@H](C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20040242572A1,2,NCCc1ccc(CN2CCCC2)cc1.O=C(O)c1ccc(C2CCCCC2)c(Cl)c1>>O=C(NCCc1ccc(CN2CCCC2)cc1)c1ccc(C2CCCCC2)c(Cl)c1 -US20100022529A1,1,Cn1ncc2cc(Oc3ccc([N+](=O)[O-])cc3F)c(Br)cc21.N=C(c1ccccc1)c1ccccc1>>Cn1ncc2cc(Oc3ccc([N+](=O)[O-])cc3F)c(N=C(c3ccccc3)c3ccccc3)cc21 -US05968982,7,O=C(O)C(Cl)(Cl)CCCCCCCCC=Cc1ccccc1>>O=C(O)C(Cl)(Cl)CCCCCCCCCCc1ccccc1 -US06090803,1,Cc1cc[nH]n1.O=C(c1ccc(F)cc1Cl)N1Cc2cccnc2Nc2ccccc21>>Cc1ccn(-c2ccc(C(=O)N3Cc4cccnc4Nc4ccccc43)c(Cl)c2)n1 -US20090176804A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cccc2[nH]ccc12>>Cc1cccc2c1ccn2C(=O)OC(C)(C)C -US20150104384A1,9,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(Br)cc2)CC1.[C-]#N>>CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(C#N)cc2)CC1 -US04363816,1,Cc1c(N)c(C(=O)[O-])n(C)c1C.O=[N+]([O-])c1ccccc1Cl>>Cc1c(Nc2ccccc2[N+](=O)[O-])c(C(=O)[O-])n(C)c1C -US08039493B2,3,CC(C)CN(Cc1ccnc(Br)c1)S(=O)(=O)c1ccccc1Cl.CS(=O)(=O)c1cccc(B(O)O)c1>>CC(C)CN(Cc1ccnc(-c2cccc(S(C)(=O)=O)c2)c1)S(=O)(=O)c1ccccc1Cl -US20050215576A1,2,CN1CCC2(CCNCC2)CC1.Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)O)cc2cn[nH]c12>>Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)N2CCC3(CCN(C)CC3)CC2)cc2cn[nH]c12 -US05135914,2,CC(C)CC(NC(=O)C(CCCCN)NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)C(O)C(=O)OC(C)C.CN=C=S>>CNC(=S)NCCCCC(NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)C(=O)NC(CC(C)C)C(O)C(=O)OC(C)C -US20050176764A1,1,CNC1CCN(Cc2ccnc(-c3cc(OC)c(OC)c(OC)c3)c2)CC1.COc1cc(-c2cccc(CCl)c2)cc(OC)c1OC>>COc1cc(-c2cccc(CN(C)C3CCN(Cc4ccnc(-c5cc(OC)c(OC)c(OC)c5)c4)CC3)c2)cc(OC)c1OC -US20040122057A1,3,COC(C(=O)NCc1ccc(C#N)cc1)c1cc(Br)ccc1F.OB(O)c1ccccc1>>COC(C(=O)NCc1ccc(C#N)cc1)c1cc(-c2ccccc2)ccc1F -US06248894B1,2,CCN.O=C(O)c1cccs1>>CCNC(=O)c1cccs1 -US20140073620A1,1,C=O.NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)cc3)ncc2C(F)(F)F)CC1>>CN1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cc2)CC1 -US20050256103A1,1,C=CCBr.COc1ccc([N+](=O)[O-])c(O)c1>>C=CCOc1cc(OC)ccc1[N+](=O)[O-] -US20090298899A1,3,N#CCc1cccc(NC(=O)c2cccc(Br)n2)c1.OB(O)c1cccc(F)c1>>N#CCc1cccc(NC(=O)c2cccc(-c3cccc(F)c3)n2)c1 -US20110269244A1,6,C=CCC1CC[C@@H](C(=O)OCc2ccccc2)N1C(=O)OC(C)(C)C>>C=CCC1CC[C@@H](C(=O)OCc2ccccc2)N1 -US20120190679A1,2,CC(=O)NCCC(N)c1ccc(Cl)cc1.CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1>>CC(=O)NCCC(NC(=O)C1(NC(=O)OC(C)(C)C)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1 -US20070149508A1,2,O=S(=O)(Cl)c1ccc(Br)cc1.OC1CCNCC1>>O=S(=O)(c1ccc(Br)cc1)N1CCC(O)CC1 -US06518306B1,8,COc1cc(C(O)c2ccc(Br)cc2)ccc1OC1CCCC1>>COc1cc(C(=O)c2ccc(Br)cc2)ccc1OC1CCCC1 -US20150152113A1,2,NNc1nncc(N2CCC(c3ccccc3)CC2)c1Cl.O=C(Cl)CC(F)(F)F>>O=C(CC(F)(F)F)NNc1nncc(N2CCC(c3ccccc3)CC2)c1Cl -US20090215780A1,2,CCCCC(=O)Nc1ccc(-c2ccc(C(=O)CC(CCc3ccccc3)C(=O)OCC)cc2)cc1.CS(N)(=O)=O>>CCCCC(=O)Nc1ccc(-c2ccc(C(=O)CC(CCc3ccccc3)C(=O)NS(C)(=O)=O)cc2)cc1 -US20090048457A1,9,O=C(O)C1CCc2cc(F)ccc2O1>>O=C(O)C1CCc2ccccc2O1 -US07741497B2,9,COC(=O)C1(C(C)=O)CCOCC1>>CC(=O)C1CCOCC1 -US07888352B2,1,CN(C)C(=O)CN1CCNCC1.O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CN(C)C(=O)CN1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1 -US20100210617A1,3,CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cc2)(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.CN(C)S(=O)(=O)n1ncc(Br)c1C1CC1>>CN(C)S(=O)(=O)n1ncc(-c2ccc(C3(c4ccc(Cl)cc4)CCN(C(=O)OC(C)(C)C)CC3)cc2)c1C1CC1 -US20060217382A1,3,COc1cc(Nc2ncc3c(C)nc(-c4cccc(Br)c4)n3n2)cc(OC)c1OC.OB(O)c1ccccc1C(F)(F)F>>COc1cc(Nc2ncc3c(C)nc(-c4cccc(-c5ccccc5C(F)(F)F)c4)n3n2)cc(OC)c1OC -US04027040,3,CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Cc1c(C=O)cccc1C(=O)c1ccc(F)cc1>>CCC=Cc1cccc(C(=O)c2ccc(F)cc2)c1C -US20060116410A1,1,BrCc1ccccc1.COC(=O)c1cc(Cl)cc(NS(C)(=O)=O)c1>>COC(=O)c1cc(Cl)cc(N(Cc2ccccc2)S(C)(=O)=O)c1 -US05532240,1,CC(=O)N1CCc2sc(C(=O)CCCCl)cc2C1.Fc1ccc2c(C3CCNCC3)noc2c1>>CC(=O)N1CCc2sc(C(=O)CCCN3CCC(c4noc5cc(F)ccc45)CC3)cc2C1 -US20120283271A1,6,COC(=O)[C@H](CC1CCCCC1)N1Cc2c(F)cccc2C1=O>>O=C(O)[C@H](CC1CCCCC1)N1Cc2c(F)cccc2C1=O -US03931247,2,CC(=O)OC(C)=O.CC(=O)c1ccc(-c2ccc(N)cc2)o1>>CC(=O)Nc1ccc(-c2ccc(C(C)=O)o2)cc1 -US20150051171A1,1,COc1cccc(-n2nnn(C)c2=O)c1CBr.Oc1ccn(-c2ccc(Br)cc2)n1>>COc1cccc(-n2nnn(C)c2=O)c1COc1ccn(-c2ccc(Br)cc2)n1 -US20110206607A1,1,CO.Oc1cc(Cl)c(-c2nc3cccc(F)n3c2Nc2ccc3c(c2)OCCO3)c(Cl)c1>>COc1cccc2nc(-c3c(Cl)cc(O)cc3Cl)c(Nc3ccc4c(c3)OCCO4)n12 -US20050032873A1,1,CCC=O.COc1cccc2c1CC(NCCCCc1c[nH]c3ccc(F)cc13)CO2>>CCCN(CCCCc1c[nH]c2ccc(F)cc12)C1COc2cccc(OC)c2C1 -US08039450B2,7,N#Cc1ccc(Oc2ccc3c(c2)COB3O)c(C=O)c1>>N#Cc1ccc(Oc2ccc3c(c2)COB3O)c(CO)c1 -US20110152257A1,3,C#Cc1ccc(C)cc1.Cc1cc2ncc(Br)cn2n1>>Cc1ccc(C#Cc2cnc3cc(C)nn3c2)cc1 -US06162818,2,NCCN.O=C1Cc2c(N=C=S)cccc2N1>>NCCNC(=S)Nc1cccc2c1CC(=O)N2 -US07582761B2,1,Clc1cccc(Cl)c1N1CCNCC1.FC(F)(F)c1ccc2nc(Cl)[nH]c2c1>>FC(F)(F)c1ccc2nc(N3CCN(c4c(Cl)cccc4Cl)CC3)[nH]c2c1 -US20140179715A1,1,N#Cc1cc(C=O)ccc1F.Oc1ccc(Cl)nc1>>N#Cc1cc(C=O)ccc1Oc1ccc(Cl)nc1 -US20060052396A1,2,CC(=O)N1CCNCC1.O=S(=O)(Cl)c1ccc(Br)cc1>>CC(=O)N1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 -US06333323B1,3,CC(=O)OC(C)=O.COC(=O)c1ccc2c(ccn2S(=O)(=O)c2ccccc2)c1>>COC(=O)c1ccc2c(c1)c(C(C)=O)cn2S(=O)(=O)c1ccccc1 -US05449682,6,CCCc1c(OC(C(=O)OC)c2ccccc2)ccc(C(C)(C)C)c1CO[SiH](C)C>>CCCc1c(OC(C(=O)O)c2ccccc2)ccc(C(C)(C)C)c1CO[SiH](C)C -US20150197530A1,6,COC(=O)c1cc(C)c(Br)s1>>Cc1cc(C(=O)O)sc1Br -US20060052315A1,2,COC(=O)Cl.Nc1ccc(-c2ccccc2C(F)(F)F)cc1>>COC(=O)Nc1ccc(-c2ccccc2C(F)(F)F)cc1 -US08481550B2,1,CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](N)C[C@@H]1O[Si](C)(C)C(C)(C)C.Fc1c(Cl)ncnc1Cl>>CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](Nc2ncnc(Cl)c2F)C[C@@H]1O[Si](C)(C)C(C)(C)C -US20140148443A1,2,CCOc1cc(Cl)c(S(=O)(=O)NC(C)(C)C)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.OCC(O)CCN1CCNCC1>>CCOc1cc(Cl)c(S(=O)(=O)NC(C)(C)C)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCC(O)CO)CC1 -US07531545B2,2,CC(C)C(NC(=O)OC(C)(C)C)C(=O)O.CNCCc1ccccc1>>CC(C)C(NC(=O)OC(C)(C)C)C(=O)N(C)CCc1ccccc1 -US20080096922A1,2,COc1cccc(C2(C(=O)Cl)CCN(c3ncccn3)CC2)c1.NS(N)(=O)=O>>COc1cccc(C2(C(=O)NS(N)(=O)=O)CCN(c3ncccn3)CC2)c1 -US20090203737A1,2,CO.Cc1ccc(S(=O)(=O)NCC(=O)O)cc1>>COC(=O)CNS(=O)(=O)c1ccc(C)cc1 -US06288082B1,1,CCOc1cc2c(Cl)c(C#N)cnc2cc1OC.Nc1ccc2cn[nH]c2c1>>CCOc1cc2c(Nc3ccc4cn[nH]c4c3)c(C#N)cnc2cc1OC -US05114949,1,COC1c2ccccc2C(=O)N1CCBr.Fc1ccc2[nH]cc(CC3CCNCC3)c2c1>>COC1c2ccccc2C(=O)N1CCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1 -US20120101099A1,6,O=C(C=Cc1ccc(Cn2cc(-c3ccc(CN4CCCC4)cc3)nn2)cc1)NOC1CCCCO1>>O=C(C=Cc1ccc(Cn2cc(-c3ccc(CN4CCCC4)cc3)nn2)cc1)NO -US08129376B2,2,CN(c1ccccc1Br)C1CCNCC1.O=C(O)CNC(=O)c1ccc(-c2ccccc2)cc1>>CN(c1ccccc1Br)C1CCN(C(=O)CNC(=O)c2ccc(-c3ccccc3)cc2)CC1 -US20070105908A1,5,CC(C)(C)OC(=O)NCc1cnc(N)s1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)NCc1cnc(NC(=O)C(F)(F)F)s1 -US08236825B2,9,CC(N)C(=O)N1N=C(c2cc(F)ccc2F)SC1(CCCN=[N+]=[N-])c1ccccc1>>CC(N)C(=O)N1N=C(c2cc(F)ccc2F)SC1(CCCN)c1ccccc1 -US20080318937A1,6,CCN(CC)C(=O)c1ccc2c(c1)Oc1c(OC)cccc1N2C1CCN(Cc2ccccc2)CC1>>CCN(CC)C(=O)c1ccc2c(c1)Oc1c(O)cccc1N2C1CCN(Cc2ccccc2)CC1 -US20110112120A9,1,CCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OB(O)c1ccc(F)cc1>>CCCc1nc(C)n(-c2ccc(F)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20060229312A1,2,Cc1ccc2c(N3CCN(CCc4cccc(NCC5CCCN5C(=O)OC(C)(C)C)c4)CC3)cccc2n1>>Cc1ccc2c(N3CCN(CCc4cccc(N5C[C@H]6CCCN6C5=O)c4)CC3)cccc2n1 -US06432993B1,1,CC(C)(C)c1cc(O)ccc1O.CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(O)c(C(C)(C)C)c2)ccc1[N+](=O)[O-] -US08188101B2,4,CC(C)(C)OC(=O)N1CCC(=O)C(C(=O)CC2CCCC2)C1.Cc1nccn1-c1ccc(NC(=N)N)cc1>>Cc1nccn1-c1ccc(Nc2nc3c(c(CC4CCCC4)n2)CN(C(=O)OC(C)(C)C)CC3)cc1 -US20110076291A1,7,CC(C)(O)C#Cc1ccc2c(n1)-c1sc(-c3ncnn3-c3ccc(F)cc3F)cc1CCO2>>CC(C)(O)CCc1ccc2c(n1)-c1sc(-c3ncnn3-c3ccc(F)cc3F)cc1CCO2 -US05395839,6,CC(C)(C)OC(=O)NCCCNc1cccc2nccn12>>NCCCNc1cccc2nccn12 -US08791267B2,1,CNCC(N)=O.Fc1ccc(Cc2ccc(OC(F)F)c(-c3cccc(Cl)c3)c2)cn1>>CN(CC(N)=O)c1ccc(Cc2ccc(OC(F)F)c(-c3cccc(Cl)c3)c2)cn1 -US20100113512A1,3,CC(C)(C)OC(=O)N(Cc1ccc(Br)cc1)C1Cc2ccccc2C1.O=Cc1cccc(B(O)O)c1>>CC(C)(C)OC(=O)N(Cc1ccc(-c2cccc(C=O)c2)cc1)C1Cc2ccccc2C1 -US20110034507A1,3,CC(=O)Nc1ccc(B(O)O)cc1.CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2cc(Br)ccc2c1>>CC(=O)Nc1ccc(-c2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3c2)cc1 -US04154740,9,NO.O=C(O)CCC(=O)c1cccs1>>O=C(CCC(O)=NO)c1cccs1 -US20150038488A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CN1C(=O)CC(C)(C)c2ccc(Br)cc21>>CN1C(=O)CC(C)(C)c2ccc(B3OC(C)(C)C(C)(C)O3)cc21 -US20110275622A1,2,CC(C)(C)OC(=O)N(CCCCC1(c2ccc(N)cc2)SCCS1)C[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c2[nH]c(=O)ccc12.COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)O)c4)cc23)c1>>COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5ccc(C6(CCCCN(C[C@H](O[Si](C)(C)C(C)(C)C)c7ccc(O)c8[nH]c(=O)ccc78)C(=O)OC(C)(C)C)SCCS6)cc5)c4)cc23)c1 -US05378690,8,CC(C)(C)OC(=O)C(Cc1cccc2ccccc12)CC(O)CN1CCOCC1>>CC(C)(C)OC(=O)C(CC(=O)CN1CCOCC1)Cc1cccc2ccccc12 -US04116956,2,NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1.O=C(Cl)c1ccccc1>>O=C(NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1)c1ccccc1 -US08048893B2,3,Cc1ccc(S(=O)(=O)n2cc(I)c(OCc3ccccc3)n2)cc1.OB(O)c1ccsc1>>Cc1ccc(S(=O)(=O)n2cc(-c3ccsc3)c(OCc3ccccc3)n2)cc1 -US20050090524A1,4,C/C=C/C=O.Nc1ccc(Cl)c(C(=O)O)c1>>Cc1ccc2c(C(=O)O)c(Cl)ccc2n1 -US20090270351A1,6,COC(=O)c1ccc(C(NC(=O)OC(C)(C)C)P(=O)(OC)OC)cc1>>COP(=O)(OC)C(NC(=O)OC(C)(C)C)c1ccc(C(=O)O)cc1 -US05192789,2,CN=C=O.Cn1c2c(c3cc(O)ccc31)CCC2NC1CC1>>CNC(=O)Oc1ccc2c(c1)c1c(n2C)C(NC2CC2)CC1 -US06713474B2,1,Nc1ncnc2[nH]cc(-c3ccc(Oc4ccccc4)cc3)c12.O=C1OCCC1Br>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCOC1=O -US06228870B1,7,CC(C)(C)OC(=O)N1CC=C(c2ccccc2C#N)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccccc2C#N)CC1 -US20130178457A1,6,COC(=O)c1cncc2cccc(Cl)c12>>O=C(O)c1cncc2cccc(Cl)c12 -US06326359B1,1,COC[C@H]1O[C@@H](n2cnc3c(NCCc4ccccc4)nc(CN)nc32)[C@H](O)[C@@H]1O.O=C1CCCCC1>>COC[C@H]1O[C@@H](n2cnc3c(NCCc4ccccc4)nc(CNC4CCCCC4)nc32)[C@H](O)[C@@H]1O -US04235926,6,CCOC(=O)C1(c2ccc(OCC)cc2)CC(F)(F)C1(F)F>>CCOc1ccc(C2(C(=O)O)CC(F)(F)C2(F)F)cc1 -US20150119393A1,2,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4cc(Cl)c(-c5ccc([C@@H]6CC[C@H](O)CC6)cc5)nc4n3COCC[Si](C)(C)C)CO[C@@H]21.O=C(Cl)N1CCOCC1>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4cc(Cl)c(-c5ccc([C@H]6CC[C@@H](OC(=O)N7CCOCC7)CC6)cc5)nc4n3COCC[Si](C)(C)C)CO[C@@H]21 -US05629406,6,CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)COc1ccc(NC(=O)OCc2ccccc2)cc1>>CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)COc1ccc(N)cc1 -US20140073650A1,1,C[C@@H](Br)C(=O)O.Cc1ccc(O)cc1>>Cc1ccc(O[C@H](C)C(=O)O)cc1 -US20050054627A1,2,COC(=O)c1cc(C(=O)O)cc(C(C)(C)C)c1.N#CCCN>>COC(=O)c1cc(C(=O)NCCC#N)cc(C(C)(C)C)c1 -US20120149721A1,2,CC(=O)Cl.COc1ccc(-c2ncnc3c(C(=O)N[C@@H]4CC[C@@H](N)CC4)c(C)[nH]c23)c(OCC2CC2)c1>>COc1ccc(-c2ncnc3c(C(=O)N[C@@H]4CC[C@@H](NC(C)=O)CC4)c(C)[nH]c23)c(OCC2CC2)c1 -US20120309739A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncc(Cl)nc4c3-c3ccccc3)cc2)CCC1.Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1>>Cc1n[nH]c(C)c1-c1cnc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2n1 -US20030008227A1,1,CCCCCCCCCCCCCCCCCCN(C)C.ClCc1ccc2ccccc2c1>>CCCCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccc2ccccc2c1 -US20020137750A1,7,Cc1c(N)cccc1C(=O)O>>Cc1c(N)cccc1CO -US07192970B2,7,COC(=O)C(=Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)OC>>COC(=O)C(Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)OC -US20020002163A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)C1=NC(N)C(=O)Nc2ccccc21>>CC(C)C1=NC(NC(=O)OC(C)(C)C)C(=O)Nc2ccccc21 -US20060041146A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1csc(N)n1>>CCOC(=O)c1csc(NC(=O)OC(C)(C)C)n1 -US08119647B2,3,COc1cccc(C=O)c1OCC1CC1.Cc1csc2nc(C[P+](c3ccccc3)(c3ccccc3)c3ccccc3)cc(=O)n12>>COc1cccc(/C=C/c2cc(=O)n3c(C)csc3n2)c1OCC1CC1 -US06617339B1,1,O=C1O[C@@H](CO)CN1c1ccccc1.Oc1cnsn1>>O=C1O[C@@H](COc2cnsn2)CN1c1ccccc1 -US20060009451A1,3,Clc1c2c(nc3ccccc13)CCCC2.OB(O)c1ccc(OCc2ccccc2)cc1>>c1ccc(COc2ccc(-c3c4c(nc5ccccc35)CCCC4)cc2)cc1 -US20140275009A1,6,Cc1nsc(N2C(=O)c3ccccc3C2=O)c1N1CCCC1>>Cc1nsc(N)c1N1CCCC1 -US20080207708A1,4,CC(C)COc1ccc(Cl)cc1Cc1nc(C(=O)O)co1.Nc1ccc(CCO)cc1N>>CC(C)COc1ccc(Cl)cc1Cc1nc(-c2nc3cc(CCO)ccc3[nH]2)co1 -US20150203511A1,7,COC(=O)c1c(-n2nnn(C)c2=O)ccc(F)c1C>>Cc1c(F)ccc(-n2nnn(C)c2=O)c1CO -US20050197350A1,2,CNc1ccnc(N[C@@H]2CC[C@H](N)CC2)n1.O=C(O)c1ccc(F)c(F)c1>>CNc1ccnc(N[C@@H]2CC[C@H](NC(=O)c3ccc(F)c(F)c3)CC2)n1 -US07501406B2,6,CC(C)(C)OC(=O)N1CCC(CN([C@@H]2CC(F)(F)CCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)CC1>>O=C1NCCC(F)(F)C[C@H]1N(CC1CCNCC1)S(=O)(=O)c1ccc(Cl)cc1 -US08183262B2,2,COCCN.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1>>COCCNS(=O)(=O)c1cccc(-c2cccc(-c3cc(-c4ccc(C(F)(F)F)cc4)cc(C)n3)n2)c1 -US20060247260A1,6,O=C(OCc1ccccc1)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1>>O=C(O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1 -US05994368,2,CC(=O)OC(C)=O.OCc1ccc2c(c1)CCCN2>>CC(=O)N1CCCc2cc(CO)ccc21 -US05750550,1,COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(CBr)C2=O.Oc1cc(C(F)(F)F)nn1-c1ccc(Cl)cn1>>COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COc1cc(C(F)(F)F)nn1-c1ccc(Cl)cn1)C2=O -US08513234B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC(C#N)CCCC(C)O>>CC(O)CCCC(C#N)N(C)C(=O)OC(C)(C)C -US20080194633A1,2,O=C=NCc1ccccc1Cl.OCCNCCO>>O=C(NCc1ccccc1Cl)N(CCO)CCO -US20140364433A1,1,Cc1ccc(-c2ncccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.Fc1ccc2oc(Cl)nc2c1>>Cc1ccc(-c2ncccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2nc3cc(F)ccc3o2)c1 -US20100173968A1,2,CC(C)(C)OC(=O)N1CC2C=C(C(=O)O)CC2C1.CNOC>>CON(C)C(=O)C1=CC2CN(C(=O)OC(C)(C)C)CC2C1 -US08440830B2,2,Cc1ccc(S(=O)(=O)N2CCc3sc(C(=O)O)cc3C2)cc1.Nc1ccccc1N>>Cc1ccc(S(=O)(=O)N2CCc3sc(C(=O)Nc4ccccc4N)cc3C2)cc1 -US08853215B2,6,COC(=O)C(=O)N1CCC(COc2ccc(C(=O)N3CCN(c4ccccc4C(C)(C)C)CC3)cc2)CC1>>CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(OCC3CCN(C(=O)C(=O)O)CC3)cc2)CC1 -US20100035871A1,1,CI.COc1ccc(-c2cc(Cl)cc3c2NC(CN=[N+]=[N-])CO3)c(C)c1>>COc1ccc(-c2cc(Cl)cc3c2N(C)C(CN=[N+]=[N-])CO3)c(C)c1 -US06887875B2,2,C1COCCN1.COc1cc(OC(F)(F)F)ccc1-c1nc(OC)c(-n2cncc2C(=O)O)cc1C>>COc1cc(OC(F)(F)F)ccc1-c1nc(OC)c(-n2cncc2C(=O)N2CCOCC2)cc1C -US04372893,7,CCOC(=O)C=Cc1ccc([N+](=O)[O-])cc1>>CCOC(=O)C=Cc1ccc(N)cc1 -US20150183801A1,3,Nc1ncc(B(O)O)cn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCCC2)c(Br)c1>>Nc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N2CCCC2)cn1 -US09067947B2,3,COc1ccc(Cl)cc1B(O)O.Nc1ncc(Cl)cc1I>>COc1ccc(Cl)cc1-c1cc(Cl)cnc1N -US20130324546A1,6,CCc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1>>CCc1cc(C2CCNCC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1 -US06900244B2,1,CCOC(=O)[C@H](C)Nc1ccccc1.CI>>CCOC(=O)[C@H](C)N(C)c1ccccc1 -US06028074,1,C=C(C)Cn1c(=O)n(C)c(=O)c2c[nH]nc21.ClCc1cccc2ccccc12>>C=C(C)Cn1c(=O)n(C)c(=O)c2cn(Cc3cccc4ccccc34)nc21 -US20060014827A1,7,CCOC(=O)c1cccc(C2=CCCC2)c1>>OCc1cccc(C2=CCCC2)c1 -US20110288091A1,1,CCC(=O)N1CCN(c2ccc(N)cc2C(F)(F)F)CC1.CCOC(=O)c1cnc2ccc(Cl)cc2c1Cl>>CCOC(=O)c1cnc2ccc(Cl)cc2c1Nc1ccc(N2CCN(C(=O)CC)CC2)c(C(F)(F)F)c1 -US20090286974A1,1,COC(=O)Cc1cccc(OCCBr)c1.NC1CCN(c2nc3ccc(Cl)cc3s2)C1>>COC(=O)Cc1cccc(OCCNC2CCN(c3nc4ccc(Cl)cc4s3)C2)c1 -US08765730B2,3,CON(C)C(=O)CC(c1ccc(Br)cc1)c1ccccc1C.Cc1cnc(F)cc1I>>Cc1cnc(F)cc1C(=O)CC(c1ccc(Br)cc1)c1ccccc1C -US20120309796A1,2,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2N.O=S(=O)(Cl)c1cccc(-c2ccccc2)c1>>CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1cccc(-c2ccccc2)c1 -US06642226B2,1,Cc1cccc(C)c1NC(=O)CCl.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCNCC2)[C@H](c2ccccc2)C1>>Cc1cccc(C)c1NC(=O)CN1CCN([C@H]2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C[C@H]2c2ccccc2)CC1 -US20100105723A1,4,Nc1cc(-c2c(F)cncc2F)c(-c2ccccc2F)nc1N.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cc(-c3c(F)cncc3F)c(-c3ccccc3F)nc2[nH]1 -US20150005232A1,3,Cc1nc(N2C[C@H]3C[C@H]3C2C(=O)O)ncc1Br.OB(O)c1cc(C(F)(F)F)cc2[nH]ncc12>>Cc1nc(N2C[C@H]3C[C@H]3C2C(=O)O)ncc1-c1cc(C(F)(F)F)cc2[nH]ncc12 -US04997840,7,CCn1cc(OC(=O)c2ccccc2)c(=O)c2ccccc21>>CCn1cc(O)c(=O)c2ccccc21 -US20130035358A1,8,COC(=O)c1cc(C(O)c2ccc(N(C)c3ccc(Cl)cc3)cn2)ccc1Br>>COC(=O)c1cc(C(=O)c2ccc(N(C)c3ccc(Cl)cc3)cn2)ccc1Br -US04264608,2,CN=C=S.COc1cccnc1CSCCN>>CNC(=S)NCCSCc1ncccc1OC -US20110166137A1,6,COc1ccc2cc(-c3ccnc(N(C)C)n3)cc(NC3CCN(C(=O)OC(C)(C)C)CC3)c2c1>>COc1ccc2cc(-c3ccnc(N(C)C)n3)cc(NC3CCNCC3)c2c1 -US07241893B2,2,CC(=O)O.Nc1cc(O)c2cc(Br)ccc2n1>>CC(=O)Nc1cc(O)c2cc(Br)ccc2n1 -US20120015969A1,6,COC(=O)[C@H]1C[C@@H](NC(=O)OC(C)(C)C)CN(c2cc(C)cc(Nc3ccn[nH]3)n2)C1>>Cc1cc(Nc2ccn[nH]2)nc(N2C[C@@H](C(=O)O)C[C@@H](NC(=O)OC(C)(C)C)C2)c1 -US20120258973A1,2,Cc1n[nH]c(C)c1C(C)N.Cn1nc(-c2ccccc2)c2c(C(F)(F)F)cc(OCC(=O)O)nc21>>Cc1n[nH]c(C)c1[C@H](C)NC(=O)COc1cc(C(F)(F)F)c2c(-c3ccccc3)nn(C)c2n1 -US04568685,1,O=C1c2ccccc2C(=O)N1CCCCBr.c1nc[nH]n1>>O=C1c2ccccc2C(=O)N1CCCCn1cncn1 -US07314937B2,2,O=S(=O)(Cl)c1cccs1.c1cc2c(cc1OCCCN1CCCCC1)CNCC2>>O=S(=O)(c1cccs1)N1CCc2ccc(OCCCN3CCCCC3)cc2C1 -US05750213,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCC(c2cccc(F)c2F)CC1>>COC=C1CCC(c2cccc(F)c2F)CC1 -US04518597,8,CC(=O)Nc1ccc(SCCCCOc2ccc3c(c2)C(C2CCCCC2)(C2CCCCC2)OC(=O)N3)cc1.OO>>CC(=O)Nc1ccc(S(=O)CCCCOc2ccc3c(c2)C(C2CCCCC2)(C2CCCCC2)OC(=O)N3)cc1 -US20090264466A1,6,COC(=O)C1(CO)CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(CO)CCNCC1 -US08748614B2,6,CC(C)(C)OC(=O)N1CCC(Nc2ccc3cnccc3c2)CC1>>c1cc2cc(NC3CCNCC3)ccc2cn1 -US06194410B1,1,CN1CCNCC1.CSc1nn2c(N)cc(Cl)nc2c1S(=O)(=O)c1ccccc1>>CSc1nn2c(N)cc(N3CCN(C)CC3)nc2c1S(=O)(=O)c1ccccc1 -US20110009454A1,7,N#Cc1ccc(Oc2ccccc2)c(F)c1>>NCc1ccc(Oc2ccccc2)c(F)c1 -US20050277619A1,6,CC(=O)OCc1nc2c(Cl)ncnc2n1CC(C)(C)C>>CC(C)(C)Cn1c(CO)nc2c(Cl)ncnc21 -US06066639,9,COC(=O)c1cc(I)cn1[Si](C(C)C)(C(C)C)C(C)C>>COC(=O)c1cccn1[Si](C(C)C)(C(C)C)C(C)C -US20060211698A1,7,Cc1nc(C)c(-c2ccc3cc(-c4c(C5CCCCC5)c5ccc(C(=O)O)cc5n4CC(=O)N4CCOCC4)ccc3n2)s1>>Cc1nc(C)c(C2CCc3cc(-c4c(C5CCCCC5)c5ccc(C(=O)O)cc5n4CC(=O)N4CCOCC4)ccc3N2)s1 -US20120282629A1,1,NNc1ccc(F)cc1F.O=Cc1ccc(O)c(O)c1>>Oc1ccc(C=NNc2ccc(F)cc2F)cc1O -US20050171195A1,1,CC(Cl)(Cl)C(=O)n1nnc2ccccc21.COc1ccc(CC(N)=O)cc1OC>>COc1ccc(CC(=O)NC(n2nnc3ccccc32)C(C)(Cl)Cl)cc1OC -US04298739,1,CC(C)I.NC1CCCCC1O>>CC(C)NC1CCCCC1O -US07432275B2,6,CCOC(=O)c1nc(Nc2ccc(C(C)(C)C)cc2)c2ccc(-c3ncccc3C)nc2n1>>Cc1cccnc1-c1ccc2c(Nc3ccc(C(C)(C)C)cc3)nc(C(=O)O)nc2n1 -US08163728B2,2,CCCCc1noc(C)c1COc1cc(C(=O)OC)[nH]n1.NCCO>>CCCCc1noc(C)c1COc1cc(C(=O)NCCO)[nH]n1 -US06071934,7,CSc1ccc(/C=C2/C(C)=C(C=O)c3cc(F)ccc32)cc1>>CSc1ccc(/C=C2/C(C)=C(CO)c3cc(F)ccc32)cc1 -US04077982,1,Fc1ccccc1CCl.OC1COC(CCl)OC1>>Fc1ccccc1COC1COC(CCl)OC1 -US20120088750A1,6,CCOC(=O)C1(F)CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(F)CCNCC1 -US20150057265A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1c(N)sc2ccc(Cl)nc12>>CCOC(=O)c1c(NC(=O)OC(C)(C)C)sc2ccc(Cl)nc12 -US20030114668A1,7,COc1cccc(C=C2NC(=O)CN(C(C)=O)C2=O)c1OC>>COc1cccc(CC2NC(=O)CN(C(C)=O)C2=O)c1OC -US20150051195A1,3,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl.OB(O)c1cccc2ncccc12>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1cccc2ncccc12 -US08389514B2,1,C[C@H]1COc2c(F)c(F)c(N)c3c(=O)c(C#N)cn1c23.NCCCc1cccnc1>>C[C@H]1COc2c(NCCCc3cccnc3)c(F)c(N)c3c(=O)c(C#N)cn1c23 -US07482448B2,2,CCCC(F)(F)CC(NC(=O)N1CCCOCC1)C(=O)O.N#CCN>>CCCC(F)(F)C[C@H](NC(=O)N1CCCOCC1)C(=O)NCC#N -US20060079548A1,6,CNC(=O)c1c(C)oc2cc(Oc3ccnc4cc(C(=O)N5CCCC5COC)sc34)ccc12>>CNC(=O)c1c(C)oc2cc(Oc3ccnc4cc(C(=O)N5CCC[C@H]5CO)sc34)ccc12 -US20110092547A1,2,CCOC(=O)C1(C)CCC(Oc2ccc(NC(=O)C(=O)OC)cn2)CC1.NN>>CCOC(=O)C1(C)CCC(Oc2ccc(NC(=O)C(=O)NN)cn2)CC1 -US20040181062A1,4,Cc1cccc(N)c1N.O=C(O)/C=C/c1ccccc1>>Cc1cccc2[nH]c(/C=C/c3ccccc3)nc12 -US05998433,2,O=C(Cl)c1ccc(-c2ccccc2)cc1.c1cc2c(o1)CNCC2>>O=C(c1ccc(-c2ccccc2)cc1)N1CCc2ccoc2C1 -US05583135,2,CNc1ccc(F)cc1.O=C(O)c1c(O)c2cccc3c2n(c1=O)CCO3>>CN(C(=O)c1c(O)c2cccc3c2n(c1=O)CCO3)c1ccc(F)cc1 -US20130064770A1,1,COc1ccccc1N1CCNCC1.O=c1cnn(CCCCCl)c(=O)n1CCF>>COc1ccccc1N1CCN(CCCCn2ncc(=O)n(CCF)c2=O)CC1 -US05416238,6,CCCCOC(OCCCC)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1>>CCCCOC(OCCCC)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CC(C)C -US05641789,3,COc1ccc2c(c1)C(=O)CC(C)(C)O2.O=Cc1cccc([N+](=O)[O-])c1>>COc1ccc2c(c1)C(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)(C)O2 -US20080193413A1,3,C=C[Mg+].O=CC1CCCCC1>>C=CC(O)C1CCCCC1 -US05463118,8,C[C@@]12CCC(CC1O)C2>>C[C@@]12CCC(CC1=O)C2 -US20110130403A1,8,CCn1ncc2c(NC3CCC(O)CC3)c(C3=NOC(CO)(CO)C3)cnc21>>CCn1ncc2c(NC3CCC(=O)CC3)c(C3=NOC(CO)(CO)C3)cnc21 -US20050020830A1,6,CC(=O)OC1CC2CC1CN(Cc1ccccc1)C2>>OC1CC2CC1CN(Cc1ccccc1)C2 -US20150031685A1,3,CC(C)(C)OC(=O)C[Zn+].C[Si](C)(C)CCOCN1C(=O)c2ccc(Br)cc2S1(=O)=O>>CC(C)(C)OC(=O)Cc1ccc2c(c1)S(=O)(=O)N(COCC[Si](C)(C)C)C2=O -US20090029994A1,3,CCCN(CC1CC1)c1ccc(C(F)(F)F)cc1C=O.C[Mg+]>>CCCN(CC1CC1)c1ccc(C(F)(F)F)cc1C(C)O -US06410780B1,6,COC(=O)CCCC=CCC1C(O)CC(OCc2ccccc2Br)C1C1OCCO1>>COC(=O)CCCC=CCC1C(O)CC(OCc2ccccc2Br)C1C=O -US20070254867A1,1,BrCC1CCCCO1.COc1cc2c(cc1O)Nc1cc(-c3ccc([N+](=O)[O-])c(OC)c3)ccc1C(=O)N2>>COc1cc2c(cc1OCC1CCCCO1)Nc1cc(-c3ccc([N+](=O)[O-])c(OC)c3)ccc1C(=O)N2 -US08785445B2,6,CCOC(=O)C1CCOc2c1cc(Cl)c(Oc1ccc(C(=O)OC(C)(C)C)cc1)c2Br>>CCOC(=O)C1CCOc2c1cc(Cl)c(Oc1ccc(C(=O)O)cc1)c2Br -US20130079328A1,3,Cc1cc(B(O)O)ccn1.NCc1ccc(Cl)nc1>>Cc1cc(-c2ccc(CN)cn2)ccn1 -US20040133008A1,2,Cc1ccc(C(=O)O)c(Cl)n1.Nc1ccc2c(c1)CN(C(=O)Cc1ccccc1)C2>>Cc1ccc(C(=O)Nc2ccc3c(c2)CN(C(=O)Cc2ccccc2)C3)c(Cl)n1 -US20130281433A1,3,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(Br)sc2c1-c1ccc(Cl)cc1.CCc1cnn2cc(B(O)O)cnc12>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3cnc4c(CC)cnn4c3)sc2c1-c1ccc(Cl)cc1 -US20090181942A1,6,COC(=O)C1CC(c2cccc(OC)c2OC)c2cc(Cl)ccc2N(Cc2ccc(OC)cc2OC)C1=O>>COc1ccc(CN2C(=O)C(C(=O)O)CC(c3cccc(OC)c3OC)c3cc(Cl)ccc32)c(OC)c1 -US20110005947A1,6,CCOC(=O)c1cnc(SC)nc1NC1(c2ccccc2)CC1>>CSc1ncc(C(=O)O)c(NC2(c3ccccc3)CC2)n1 -US20040063698A1,2,CCOC(=O)C(C)(C)C(O)c1ccc(OCc2cc(C)nc3ccccc23)cc1.NO>>Cc1cc(COc2ccc(C(O)C(C)(C)C(=O)NO)cc2)c2ccccc2n1 -US20050038035A1,1,CC(C)(C)OC(=O)Nc1nc(CCO)cs1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)OC(=O)Nc1nc(CCOc2ccc([N+](=O)[O-])cc2)cs1 -US20150038528A1,1,BrCc1ccccc1.COC(=O)c1ncc2cc(Br)ccc2c1O>>COC(=O)c1ncc2cc(Br)ccc2c1OCc1ccccc1 -US20110082129A1,4,CCCC(=O)c1cccnc1.NNc1ccccc1>>CCc1c(-c2cccnc2)[nH]c2ccccc12 -US07605259B2,2,NCC=CCN1CCN(c2cccc(Cl)c2Cl)CC1.O=C(O)c1ccc(O)cc1>>O=C(NCC=CCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(O)cc1 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.CCNC(C)C>>CC#CCOc1cc(N(CC)C(C)C)ncn1 -US20140364414A1,1,CN1C(=O)Nc2ccc(Br)cc2S1(=O)=O.C[Si](C)(C)CCOCCl>>CN1C(=O)N(COCC[Si](C)(C)C)c2ccc(Br)cc2S1(=O)=O -US20150266870A1,1,CCN(CC)CCO.Nc1ncc(O)cn1>>CCN(CC)CCOc1cnc(N)nc1 -US20120101103A1,2,CCOC(=O)C1CCOc2c1cc(Cl)c(Oc1ccc(C(=O)O)cc1)c2Br.Nc1cccc(-c2ccc(Cl)cc2)n1>>CCOC(=O)C1CCOc2c1cc(Cl)c(Oc1ccc(C(=O)Nc3cccc(-c4ccc(Cl)cc4)n3)cc1)c2Br -US05866565,2,CC(C)N(C=Nc1ccncc1O)C(C)C.CN(C)C(=O)Cl>>CC(C)N(C=Nc1ccncc1OC(=O)N(C)C)C(C)C -US20070249620A1,1,CCOP(OCC)OCC.Cc1cc(CBr)ccc1[N+](=O)[O-]>>CCOP(=O)(Cc1ccc([N+](=O)[O-])c(C)c1)OCC -US07732446B1,6,COc1ccc(CNC(=O)c2cnc(CNC(=O)OC(C)(C)C)c3c(OC)cc(OC)cc23)cc1>>COc1ccc(CNC(=O)c2cnc(CN)c3c(OC)cc(OC)cc23)cc1 -US06262045B1,1,CCI.CCOC(=O)c1cc2cc(F)ccc2[nH]1>>CCOC(=O)c1cc2cc(F)ccc2n1CC -US20040106604A1,7,COC(=O)C=Cc1ccc2c(-c3c(-c4cccc(C)n4)nn4c3CCC4)ccnc2c1>>COC(=O)CCc1ccc2c(-c3c(-c4cccc(C)n4)nn4c3CCC4)ccnc2c1 -US08569535B2,3,CC(C)=CB1OC(C)(C)C(C)(C)O1.CCOC(=O)C1(NC(=O)c2cccc(C(F)(F)F)c2I)Cc2ccccc2C1>>CCOC(=O)C1(NC(=O)c2cccc(C(F)(F)F)c2C=C(C)C)Cc2ccccc2C1 -US06638919B2,1,C[C@H](N)C(=O)O.OC1CCCC1>>C[C@H](N)C(=O)OC1CCCC1 -US05736487,1,COC(=O)Nc1ccc(O)cc1C.ClCc1nc2ccccc2s1>>COC(=O)Nc1ccc(OCc2nc3ccccc3s2)cc1C -US20070249670A1,7,O=C(CC[C@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1[N+](=O)[O-])C(=O)OCc1ccccc1)OCc1ccccc1>>Nc1cc(-c2ccc(F)c(F)c2)ccc1C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1 -US08993575B2,2,CCOC(=O)c1ccccc1.NN>>NNC(=O)c1ccccc1 -US20140243315A1,6,CCCCNc1ncc2c(-c3ccc(F)cc3)cn([C@@H]3CC[C@@H](O[Si](C)(C)C(C)(C)C)CC3)c2n1>>CCCCNc1ncc2c(-c3ccc(F)cc3)cn([C@@H]3CC[C@@H](O)CC3)c2n1 -US07858624B2,2,CS(=O)(=O)Cl.Cc1cccc(-c2c(F)cccc2C(OCCO)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1>>Cc1cccc(-c2c(F)cccc2C(OCCOS(C)(=O)=O)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1 -US08658801B2,6,C#Cc1cc2cn[nH]c2c(C(=O)OC)c1N>>C#Cc1cc2cn[nH]c2c(C(=O)O)c1N -US06235731B1,7,CCOC(=O)CCc1cccc(NC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)Nc1cccc(CCCO)c1 -US20150232445A1,1,BrC1CCC1.C[C@H]1CCc2c(ccc(Br)c2O)N1C(=O)C1CC1>>C[C@H]1CCc2c(ccc(Br)c2OC2CCC2)N1C(=O)C1CC1 -US08952169B2,3,CC(=O)c1cc(C(=O)NS(=O)(=O)N2CCC2)c(F)cc1OCC12CC3CC(CC(C3)C1)C2.C[Mg+]>>CC(C)(O)c1cc(C(=O)NS(=O)(=O)N2CCC2)c(F)cc1OCC12CC3CC(CC(C3)C1)C2 -US20070072792A1,3,C=CCCNc1cc(C(=O)NC(CC(C)CCC=C)C2CC(C)C(=O)O2)cc(OC)n1>>COc1cc2cc(n1)NCCC=CCCC(C)CC(C1CC(C)C(=O)O1)NC2=O -US20080064689A1,3,CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C.CCCCNC[C@@H]1CC(c2ccc(Br)cn2)=NO1>>CCCCNC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1 -US20150175557A1,6,COC(=O)C1CC(=O)C1(C)C>>CC1(C)C(=O)CC1C(=O)O -US20120059028A1,6,CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccc(CC)cc1)CCC3>>CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(CC)cc1)CCC3 -US20030199520A1,2,CC(C)(C)OC(=O)[C@H](N)CN1C(=O)c2ccccc2C1=O.COc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>COc1cc(C)c(S(=O)(=O)N[C@H](CN2C(=O)c3ccccc3C2=O)C(=O)OC(C)(C)C)c(C)c1 -US09073940B2,1,C1COCCN1.O=C(c1nn(C2CCCN(CCCl)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1>>O=C(c1nn(C2CCCN(CCN3CCOCC3)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 -US04960888,1,Nc1cc(Cl)nc(N)n1.Oc1ccc(Cl)cc1Cl>>Nc1cc(Oc2ccc(Cl)cc2Cl)nc(N)n1 -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)C1CC1c1ccccc1>>Cc1nc(NC(=O)C2CC2c2ccccc2)sc1C(=O)NCc1ccccc1 -US04432979,1,CO.O=c1[nH]cc(-c2ccncn2)cc1Br>>Cn1cc(-c2ccncn2)cc(Br)c1=O -US20030109527A1,2,C1COCCN1.O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)Cl)c1Cl>>O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1Cl -US20150105427A1,1,ClCc1ccc(Cl)nc1.O=C(N=C1NCCS1)C(F)(F)F>>O=C(N=C1SCCN1Cc1ccc(Cl)nc1)C(F)(F)F -US20060025383A1,1,COc1cc(CO)cc(OC)c1OC.Clc1ncnc2[nH]cc(I)c12>>COc1cc(Cn2cc(I)c3c(Cl)ncnc32)cc(OC)c1OC -US20140024634A1,1,CCc1cc(O)c(F)cc1-c1ccc2c(-c3nc4c([nH]3)CCN(C(=O)c3cnc(Cl)cn3)C4)n[nH]c2c1.CN(C)[C@@H]1CCNC1>>CCc1cc(O)c(F)cc1-c1ccc2c(-c3nc4c([nH]3)CCN(C(=O)c3cnc(N5CC[C@@H](N(C)C)C5)cn3)C4)n[nH]c2c1 -US20090221663A1,2,NC1CCCCC1.O=C(O)c1cnn(-c2ccc(Br)cc2)c1C1CC1>>O=C(NC1CCCCC1)c1cnn(-c2ccc(Br)cc2)c1C1CC1 -US20100280049A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.Nc1ccccc1Br>>CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccccc2Br)CC1 -US20130217664A1,1,CCc1ccccc1N.Clc1cc2c(cn1)ncn2C1CC1>>CCc1ccccc1Nc1cc2c(cn1)ncn2C1CC1 -US05827865,6,COC(=O)C(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)OC>>COC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O -US07179812B2,1,Clc1ncc(CCCCn2ccnn2)cn1.OCc1coc(C=Cc2ccc(C(F)(F)F)cc2F)n1>>Fc1cc(C(F)(F)F)ccc1C=Cc1nc(COc2ncc(CCCCn3ccnn3)cn2)co1 -US20100152192A1,1,CC(C)CCBr.CCOC(=O)c1c(/C=C/c2cccc(OC(F)F)c2O)nc2sccn12>>CCOC(=O)c1c(/C=C/c2cccc(OC(F)F)c2OCCC(C)C)nc2sccn12 -US20090018345A1,6,Cc1cc(Oc2c(F)cc(C(F)(F)F)cc2Cl)nn1C(=O)OC(C)(C)C>>Cc1cc(Oc2c(F)cc(C(F)(F)F)cc2Cl)n[nH]1 -US20020026060A1,1,CCCCCC(CO)c1ccc2c(c1)C(C)(C)CCN2CC.COC(=O)c1ccc(O)cc1>>CCCCCC(COc1ccc(C(=O)OC)cc1)c1ccc2c(c1)C(C)(C)CCN2CC -US20100137610A1,6,CCOC(=O)c1cc2cc(OCCOC)cc([N+](=O)[O-])c2[nH]1>>COCCOc1cc([N+](=O)[O-])c2[nH]c(C(=O)O)cc2c1 -US08426420B2,2,CCOC(=O)Cl.C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1>>CCOC(=O)N1CCN(C(=O)OC(C)(C)C)C[C@H]1C -US20150119362A1,1,C1CCNC1.Clc1cc(Cl)c2c(n1)CCC2>>Clc1cc(N2CCCC2)nc2c1CCC2 -US20040242659A1,2,CC(C)N=C=O.OCCc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3ccc(C(F)(F)F)cc3)n2)cc1>>CC(C)NC(=O)OCCc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3ccc(C(F)(F)F)cc3)n2)cc1 -US08183262B2,3,CC(C)(C)NS(=O)(=O)c1cccc(B(O)O)c1.Cc1cc(-c2cc(C(F)(F)F)nc(-c3ccnc(Cl)c3)n2)ccc1Cl>>Cc1cc(-c2cc(C(F)(F)F)nc(-c3ccnc(-c4cccc(S(=O)(=O)NC(C)(C)C)c4)c3)n2)ccc1Cl -US20100056516A1,2,NCCc1ccccc1.O=C(O)c1ccc2c(c1)CN(c1cc(=O)n(OCc3ccccc3)c3ncccc13)CC2>>O=C(NCCc1ccccc1)c1ccc2c(c1)CN(c1cc(=O)n(OCc3ccccc3)c3ncccc13)CC2 -US07087273B2,1,C1=COCCC1.O=C(O)c1ccc(O)cc1>>O=C(O)c1ccc(OC2CCCCO2)cc1 -US20060116410A1,1,Cc1cccc(C(=O)NCc2ccc(C#N)cc2N)c1.O=C(CCl)Nc1ccccc1>>Cc1cccc(C(=O)NCc2ccc(C#N)cc2NCC(=O)Nc2ccccc2)c1 -US07189851B2,6,CCOC(=O)c1cnc(-c2cc(Cc3ccc(F)cc3F)nc3c2C(=O)N2CCC[C@@H]32)cn1>>O=C(O)c1cnc(-c2cc(Cc3ccc(F)cc3F)nc3c2C(=O)N2CCC[C@@H]32)cn1 -US20110086853A1,2,CC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCC(F)(F)CC1.O[C@@H]1CCNC1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CC[C@@H](O)C3)ccc2n1CC1CCC(F)(F)CC1 -US04659516,2,CCCCCCN.NCCC(=O)O>>CCCCCCNC(=O)CCN -US20030225128A1,7,COC(=O)c1cc(Br)ccc1N>>Nc1ccc(Br)cc1CO -US20100249123A1,4,CC(=O)NNC(=O)C(C)(C)c1ccc([N+](=O)[O-])cc1>>Cc1nnc(C(C)(C)c2ccc([N+](=O)[O-])cc2)o1 -US20120010207A1,7,COc1ccc(Cl)cc1C(C)=O>>COc1ccc(Cl)cc1C(C)O -US06136982,3,CC(C)=O.CCOC(=O)CC#N>>CCOC(=O)C(C#N)=C(C)C -US05326863,2,COC(=O)[C@@H]1NC(=O)[C@H]1CCCNC(=NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)[C@H]1[C@H](CCCNC(=NC(=O)OCc2ccccc2)NC(=O)OCc2ccccc2)C(=O)N1S(=O)(=O)c1ccc(C)cc1 -US20080176862A1,3,CCCC[Sn](CCCC)(CCCC)c1nccc(OC)n1.CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2ccc(F)c(Br)c2)N=C1N>>COc1ccnc(-c2cc(C3(c4ccc(OS(C)(=O)=O)cc4)N=C(N)N(C)C3=O)ccc2F)n1 -US06468998B1,2,N[C@H]1CCN(CCc2ccc(F)cc2)C1.O=S(=O)(Cl)C12CC3CC(CC(C3)C1)C2>>O=S(=O)(N[C@H]1CCN(CCc2ccc(F)cc2)C1)C12CC3CC(CC(C3)C1)C2 -US07932390B2,9,CCOC(=O)c1cnc(Cl)c2c(COc3cccc(-c4nnn(Cc5ccc(OC)cc5)n4)c3)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3cccc(-c4nnn(Cc5ccc(OC)cc5)n4)c3)csc12 -US20080269500A1,2,Nc1cccc(F)c1F.O=C(Br)CBr>>O=C(CBr)Nc1cccc(F)c1F -US20090281142A1,2,CC1(C)OCC(c2csc(N)n2)O1.CS(=O)(=O)c1ccc(/C(=C\C2CCCC2)C(=O)O)cc1Cl>>CC1(C)OCC(c2csc(NC(=O)/C(=C/C3CCCC3)c3ccc(S(C)(=O)=O)c(Cl)c3)n2)O1 -US08859608B2,3,CC(C)(C)OC(=O)N1CCC(=O)C[C@H]1C(=O)OCc1ccccc1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1CCN(C(=O)OC(C)(C)C)[C@H](C(=O)OCc2ccccc2)C1 -US20050080124A1,2,COc1ccc(N)cc1-c1c(F)cnn1C.O=C=Nc1ccc(Br)cc1>>COc1ccc(NC(=O)Nc2ccc(Br)cc2)cc1-c1c(F)cnn1C -US20150045378A1,1,CCOC(=O)CC(c1cc(Cl)ncn1)C1CC1.COc1ccc(F)c(-c2ncc(CO)cc2OC2CCCCO2)c1>>CCOC(=O)CC(c1cc(OCc2cnc(-c3cc(OC)ccc3F)c(OC3CCCCO3)c2)ncn1)C1CC1 -US06583154B1,1,C1COCCN1.Cc1nc(Cl)c2nc(-c3ccccc3)cc-2[nH]1>>Cc1nc(N2CCOCC2)c2nc(-c3ccccc3)cc-2[nH]1 -US20110130396A1,3,COc1ccc(B(O)O)cc1OC.Ic1cnc2sc(NCc3ccccc3)nn12>>COc1ccc(-c2cnc3sc(NCc4ccccc4)nn23)cc1OC -US20130109710A1,6,COC1CCC2(CCC(CO[Si](C)(C)C(C)(C)C)CC2)CC1>>COC1CCC2(CCC(CO)CC2)CC1 -US20140163023A1,2,C[C@H]1COCCN1c1nc2c(c(-c3ccc(N)cc3)n1)CN(C(=O)OC(C)(C)C)C2.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1nc2c(c(-c3ccc(NC(=O)Oc4ccccc4)cc3)n1)CN(C(=O)OC(C)(C)C)C2 -US20030134853A1,10,Cc1cc(C(=O)OC(C)(C)C)ccc1Br.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1ccc(Br)c(CBr)c1 -US05256824,7,O=C1C=CCC1(c1ccccc1)c1ccccc1>>OC1C=CCC1(c1ccccc1)c1ccccc1 -US20140378475A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1c(Br)cccc1-n1c(=O)c2ccccc2n(C)c1=O>>Cc1c(B2OC(C)(C)C(C)(C)O2)cccc1-n1c(=O)c2ccccc2n(C)c1=O -US06984653B2,1,FC(F)(F)c1ccc(/C=C/c2nc(CCl)co2)cc1.Oc1ccc(CCCCCl)cc1>>FC(F)(F)c1ccc(/C=C/c2nc(COc3ccc(CCCCCl)cc3)co2)cc1 -US08034810B2,2,CCCOc1ccc(S(=O)(=O)Cl)cc1.N[C@H](Cc1ccccc1)C(=O)NO>>CCCOc1ccc(S(=O)(=O)N[C@H](Cc2ccccc2)C(=O)NO)cc1 -US20130040930A1,1,C[C@@H]1CCS(=O)(=O)N1.Cc1cnc(N2CCN(C(=O)c3ccc(I)cc3F)CC2)c(C2CC2)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4[C@H](C)CCS4(=O)=O)cc3F)CC2)c(C2CC2)c1 -US07723367B2,3,N#Cc1cc(F)cnc1Cl.OB(O)c1ccc(F)cc1>>N#Cc1cc(F)cnc1-c1ccc(F)cc1 -US04783467,1,CCOC(=O)CN.Cc1cc(-c2ccc(O)nc2)cc(C=O)c1N>>CCOC(=O)CNCc1cc(-c2ccc(O)nc2)cc(C)c1N -US20060142572A1,1,C[C@H](N)CO.O=C(CNc1nc(Cl)ncc1Cl)NC(CO)c1cccc(Cl)c1>>CC(CO)Nc1ncc(Cl)c(NCC(=O)NC(CO)c2cccc(Cl)c2)n1 -US06391874B1,1,Cn1c(C=O)cnc1-c1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1.NC(=O)[C@@H]1CCCN1>>Cn1c(CN2CCC[C@H]2C(N)=O)cnc1-c1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1 -US08546405B2,6,CC(C)c1ccc2c(Nc3cccc(C(=O)Nc4ccc(Sc5ccc(NC(=O)OC(C)(C)C)cc5)c(Nc5ncnc6nc(C(C)C)ccc56)c4)c3)ncnc2n1>>CC(C)c1ccc2c(Nc3cccc(C(=O)Nc4ccc(Sc5ccc(N)cc5)c(Nc5ncnc6nc(C(C)C)ccc56)c4)c3)ncnc2n1 -US20030087902A1,1,CCI.CCOC(=O)c1c(-c2ccc(OCC3CC3)cc2)c2cc(O)ccc2n1Cc1cccc(OC)c1>>CCOC(=O)c1c(-c2ccc(OCC3CC3)cc2)c2cc(OCC)ccc2n1Cc1cccc(OC)c1 -US04066457,7,O=C(O)CCC(=O)Nc1ccc([N+](=O)[O-])cc1>>Nc1ccc(NC(=O)CCC(=O)O)cc1 -US20140371201A1,2,COc1cc(Br)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Cl)ccc21.Nc1ccon1>>COc1cc(Br)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Nc3ccon3)ccc21 -US08003800B2,2,C=CCOc1c(C)cc(C(=O)NN)cc1C.Cc1c(CC(C)C)csc1C(=O)O>>C=CCOc1c(C)cc(C(=O)NNC(=O)c2scc(CC(C)C)c2C)cc1C -US20030092720A1,6,COc1ccc(Cn2nnc(-c3cnc4cc(C(=O)Nc5nc(C(C)C)cs5)ccn4c3=O)n2)cc1>>CC(C)c1csc(NC(=O)c2ccn3c(=O)c(-c4nn[nH]n4)cnc3c2)n1 -US06271251B1,2,CCOC(=O)c1cc2c(C)ccc(OCCO)c2[nH]1.CS(=O)(=O)Cl>>CCOC(=O)c1cc2c(C)ccc(OCCOS(C)(=O)=O)c2[nH]1 -US20070049537A1,6,COC(=O)C1(Oc2ccc(Cc3cc([C@@]4(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3Cl)cc2)CCCC1>>O=C(O)C1(Oc2ccc(Cc3cc([C@@]4(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3Cl)cc2)CCCC1 -US04797401,1,CC(=O)N1CCNCC1.Cc1cc(F)ccc1[N+](=O)[O-]>>CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(C)c2)CC1 -US08329729B2,2,CNc1ccccc1.O=C(Br)CBr>>CN(C(=O)CBr)c1ccccc1 -US20140249104A1,1,C[C@@]1(c2cc(N)ccc2F)C[C@@H](C(F)(F)F)OC(NC(=O)c2ccccc2)=N1.Clc1ccc2nc(Cl)oc2c1>>C[C@@]1(c2cc(Nc3nc4ccc(Cl)cc4o3)ccc2F)C[C@@H](C(F)(F)F)OC(NC(=O)c2ccccc2)=N1 -US20080269200A1,2,CCCS(=O)(=O)Cl.NC(=O)c1cc(-c2ccc(Cl)cc2)cc2c(C3CCNCC3)c[nH]c12>>CCCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc(Cl)cc4)cc23)CC1 -US20120015928A1,2,O=C(O)C1(c2ccc(Cl)cc2)CC1.OC1CCNC1>>O=C(N1CCC(O)C1)C1(c2ccc(Cl)cc2)CC1 -US20100227870A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(F)c(Cl)c2Cl)CC1>>Fc1ccc(N2CCNCC2)c(Cl)c1Cl -US20110301142A1,6,COC(=O)c1ncn(Cc2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)n1>>Cc1noc(-c2ccc(Cn3cnc(C(=O)O)n3)cc2)c1NC(=O)OC(C)c1ccccc1Cl -US07507740B2,1,ClCCCn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2cccc(C(F)(F)F)c2)c(Cl)c1>>FC(F)(F)c1cccc(Oc2ccc(Nc3ncnc4ccn(CCCCl)c34)cc2Cl)c1 -US20100160255A1,1,CC1(C)CC2(CCCN(C3CCN(C(=O)c4cc(Cl)nc5ccccc45)CC3)C2)C(=O)O1.OC1CCNCC1>>CC1(C)CC2(CCCN(C3CCN(C(=O)c4cc(N5CCC(O)CC5)nc5ccccc45)CC3)C2)C(=O)O1 -US09096607B2,1,CC(c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(O)cc1.COC(=O)CBr>>COC(=O)COc1ccc(C(C)(c2ccc(O)cc2)c2ccc(O)cc2)cc1 -US08796253B2,1,CCOC(=O)c1ccc(O)cc1.COCCOCCBr>>CCOC(=O)c1ccc(OCCOCCOC)cc1 -US20140080798A1,2,CC(C)(C)OC(=O)N1CCNCC1.Nc1ccc(C(=O)O)cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(N)cc2)CC1 -US07737136B2,1,CNc1ccccc1.O=[N+]([O-])c1cc(Cl)ccc1F>>CN(c1ccccc1)c1ccc(Cl)cc1[N+](=O)[O-] -US05607939,4,C=O.OCCC(CO)(c1ccccc1)c1ccccc1>>OCCC1(c2ccccc2)COCc2ccccc21 -US05736550,6,CC(C)(C)OC(=O)N(CCN(Cc1ccc(F)cc1)C(=O)OC(C)(C)C)CCN1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)N(CCN)CCN(Cc1ccc(F)cc1)C(=O)OC(C)(C)C -US06864255B2,1,COc1cc(Nc2ncnc(-n3c(Cl)nc4ccccc43)n2)cc(OC)c1OC.NC(=O)c1cccc(N)c1>>COc1cc(Nc2ncnc(-n3c(Nc4cccc(C(N)=O)c4)nc4ccccc43)n2)cc(OC)c1OC -US20040063658A1,3,C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(Br)ncnc21.OB(O)c1ccsc1>>C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(-c3ccsc3)ncnc21 -US04128579,9,CC1=CC(=O)CC(C)C1.NO>>CC1=CC(=NO)CC(C)C1 -US20130296281A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C(N)Cc1c[nH]c2cc(-c3ccc(Oc4ccccc4)cc3)ccc12>>CCOC(=O)C(Cc1c[nH]c2cc(-c3ccc(Oc4ccccc4)cc3)ccc12)NC(=O)OC(C)(C)C -US20020193389A1,1,CCOC(=O)C1CCNCC1.N#Cc1cccc(F)c1>>CCOC(=O)C1CCN(c2cccc(C#N)c2)CC1 -US20060025474A1,1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(C#CC(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c1.O=C1CCC[C@@H](CO)O1>>CCC(CC)(c1ccc(C#CC(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(OC[C@@H]2CCCC(=O)O2)c(C)c1 -US20060058361A1,6,COc1ccc2c(ccn2C)c1F>>Cn1ccc2c(F)c(O)ccc21 -US08809538B2,2,CC(C)(C)OC(=O)N1CCC(CCC(=O)c2ccccc2NCCCNC(=O)OCc2ccccc2)CC1.COC(=O)C(=O)Cl>>COC(=O)C(=O)N(CCCNC(=O)OCc1ccccc1)c1ccccc1C(=O)CCC1CCN(C(=O)OC(C)(C)C)CC1 -US20120108828A1,7,CCCCc1oc2ccc([N+](=O)[O-])cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1>>CCCCc1oc2ccc(N)cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1 -US20140005146A1,3,COC(=O)C(C)(C)C(C)Nc1c(C(N)=O)cnn2cc(Br)cc12.OB(O)c1ccccc1>>COC(=O)C(C)(C)C(C)Nc1c(C(N)=O)cnn2cc(-c3ccccc3)cc12 -US05952306,6,CCOC(=O)[C@H](CNC(=O)CNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccccc1>>CCOC(=O)[C@H](CNC(=O)CN)NS(=O)(=O)c1ccccc1 -US08975286B2,1,CC(C)(C)C=O.COc1ccc(N)c([N+](=O)[O-])c1>>COc1ccc(NCC(C)(C)C)c([N+](=O)[O-])c1 -US06951879B2,3,C#CCCCO.O=S(=O)(Oc1ccc2c(-c3ccc(Br)cc3)nsc2c1)C(F)(F)F>>OCCCC#Cc1ccc2c(-c3ccc(Br)cc3)nsc2c1 -US06372759B1,2,C[SiH](C)Oc1c(C(C)(C)C)ccc(N)c1NC(=O)c1ccc(C(C)(C)C)cc1.O=C(O)c1ccc2cc[nH]c2c1>>C[SiH](C)Oc1c(C(C)(C)C)ccc(NC(=O)c2ccc3cc[nH]c3c2)c1NC(=O)c1ccc(C(C)(C)C)cc1 -US20120142724A1,1,CCI.C[C@@H](CO)N1C(=O)c2ccccc2C1=O>>CCOC[C@H](C)N1C(=O)c2ccccc2C1=O -US07326699B2,1,C1COCCN1.Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@@H]1C[C@@H](CNC(=O)NCCBr)C1>>Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@@H]1C[C@@H](CNC(=O)NCCN2CCOCC2)C1 -US07244722B2,1,CC1CN(c2nccnc2Cl)CCN1C(=O)OC(C)(C)C.OCCO>>CC1CN(c2nccnc2OCCO)CCN1C(=O)OC(C)(C)C -US20020173664A1,2,CC(=O)Cl.C[C@@H]1NC(=O)OC1=O>>CC(=O)N1C(=O)OC(=O)[C@@H]1C -US05296612,1,CNC/C=C/C#CC(C)(C)C.ClCc1cccc2ccccc12>>CN(C/C=C/C#CC(C)(C)C)Cc1cccc2ccccc12 -US08329729B2,2,Nc1ccnnc1.O=C(Cl)CCl>>O=C(CCl)Nc1ccnnc1 -US20110250137A1,2,CC(C)(C)OC(=O)N[C@@H](C[C@@H](O)CNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@@H](C[C@H](CNC(=O)OCc1ccccc1)OS(C)(=O)=O)C(=O)OC(C)(C)C -US06995179B2,2,C#CC(=O)O.N#CCCO>>C#CC(=O)OCCC#N -US07030142B1,1,O=C1Cc2cc(CCCl)c(Cl)cc2N1.c1ccc2c(N3CCNCC3)nsc2c1>>O=C1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1 -US08426420B2,2,CCCCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)O)n(-c3ccccc3)n2)CC1.O=C(OCc1ccccc1)[C@@H]1CCCN1>>CCCCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)OCc3ccccc3)n(-c3ccccc3)n2)CC1 -US06242470B1,2,Nc1ccc(O)cc1Cl.O=C(Cl)CC12CC3CC(CC(C3)C1)C2>>O=C(CC12CC3CC(CC(C3)C1)C2)Nc1ccc(O)cc1Cl -US06562823B1,6,Cc1ncc(CN2CCN(c3cccc4ccc(OCc5ccccc5)cc34)C(=O)C2)n1Cc1ccc(C#N)c(F)c1>>Cc1ncc(CN2CCN(c3cccc4ccc(O)cc34)C(=O)C2)n1Cc1ccc(C#N)c(F)c1 -US20100204207A1,1,C=O.Cc1cc2c(c(C)c1C(F)(F)F)N(CC1CCNCC1)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1>>Cc1cc2c(c(C)c1C(F)(F)F)N(CC1CCN(C)CC1)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1 -US20080255078A1,6,CCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1cccc(OCCOCCOC(C)=O)c1>>CCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1cccc(OCCOCCO)c1 -US04533731,1,CC(CCn1nc(N)c2cc(Cl)ccc21)N1CCCCC1.CCN(CC)CCCBr>>CCN(CC)CCCNc1nn(CCC(C)N2CCCCC2)c2ccc(Cl)cc12 -US07064124B2,7,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccc(OC)nc3OC)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)Nc3ccc(OC)nc3OC)c2)=C(C)C1=O -US07381719B2,3,CCC[Mg+].COc1ccc(CN2CCCC(C(=O)N(C)OC)C2)cc1>>CCCC(=O)C1CCCN(Cc2ccc(OC)cc2)C1 -US07732618B2,1,BrCc1ccccc1.CCCc1nc2c(NS(=O)(=O)c3cccc(F)c3)cccc2n1CC(=O)OC(C)(C)C>>CCCc1nc2c(N(Cc3ccccc3)S(=O)(=O)c3cccc(F)c3)cccc2n1CC(=O)OC(C)(C)C -US05100912,6,COc1ccc(C[C@H]2CCCN2C(=O)C(F)(F)F)cc1OC>>COc1ccc(C[C@H]2CCCN2)cc1OC -US20020177578A1,6,COC(=O)c1nc(OC)ccc1OCc1ccccc1>>COc1ccc(OCc2ccccc2)c(C(=O)O)n1 -US20130178459A1,3,CC1(C)OB(c2ccc3cn[nH]c3c2)OC1(C)C.COc1ccc2[nH]c(=O)c3sccc3c2c1Br>>COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc2cn[nH]c2c1 -US20110124642A1,2,Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O.O=C(O)Cc1ccc2ccccc2c1>>O=C(Cc1ccc2ccccc2c1)Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O -US20090181942A1,6,COC(=O)CCc1cnc(C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c(C(F)F)nnc32)o1>>COc1cccc([C@H]2O[C@H](Cc3ncc(CCC(=O)O)o3)c3nnc(C(F)F)n3-c3ccc(Cl)cc32)c1OC -US07176242B2,3,CB1OB(C)OB(C)O1.COC(=O)c1cc(Br)cc(CO)c1>>COC(=O)c1cc(C)cc(CO)c1 -US20060276518A1,2,COC(=O)C(N)Cc1ccc(Br)cc1.O=C(O)c1cc(Cl)ccc1O>>COC(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)c1cc(Cl)ccc1O -US05710157,7,CCOC(=O)C(=Cc1cc(OC)ccc1OC)C(C)=O>>CCOC(=O)C(Cc1cc(OC)ccc1OC)C(C)=O -US05521170,9,[N-]=[N+]=NCc1ccccc1-c1ccccc1C(=O)Nc1ccc(C(=O)N2CCCc3ccccc32)cc1>>NCc1ccccc1-c1ccccc1C(=O)Nc1ccc(C(=O)N2CCCc3ccccc32)cc1 -US20080176857A1,2,CCc1cc2c(N3CCNCC3)nc(SCC(=O)OC)nc2s1.O=C(Cl)c1ccc(-n2cccn2)cc1>>CCc1cc2c(N3CCN(C(=O)c4ccc(-n5cccn5)cc4)CC3)nc(SCC(=O)OC)nc2s1 -US05344828,2,CCOC(=O)Cl.c1ccc2c(c1)Cc1ccccc1C(N1CCNCC1)=N2>>CCOC(=O)N1CCN(C2=Nc3ccccc3Cc3ccccc32)CC1 -US05326760,1,CC(C)C[C@H](N[C@H](CCO)C(=O)OC(C)(C)C)C(=O)NCc1ccccc1.O=C1NC(=O)c2cc(Br)ccc21>>CC(C)C[C@H](N[C@H](CCN1C(=O)c2ccc(Br)cc2C1=O)C(=O)OC(C)(C)C)C(=O)NCc1ccccc1 -US07786163B2,9,CC(C)(C)OC(=O)NC1(c2ccccc2)CC2SCC(C(N)=O)N2C1=O>>CC(C)(C)OC(=O)NC1(c2ccccc2)CC2SCC(C#N)N2C1=O -US06914062B2,3,C=C[Sn](CCCC)(CCCC)CCCC.O=[N+]([O-])c1ccc(Cl)cc1F>>C=Cc1ccc([N+](=O)[O-])c(F)c1 -US20100197908A1,1,C=O.CC(C)(C)OC(=O)N1CCC(NCc2ccccc2)CC1>>CN(Cc1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1 -US08735417B2,3,Clc1ccnc(Cl)n1.OB(O)C1CC1>>Clc1nccc(C2CC2)n1 -US05866567,7,O=C1[C@H]2CCC[C@H]2Nc2ccccc2N1Cc1cccc([N+](=O)[O-])c1>>Nc1cccc(CN2C(=O)[C@H]3CCC[C@H]3Nc3ccccc32)c1 -US20120142665A1,6,CC(C)(C)OC(=O)Nc1ccn2nc(-c3cccnc3)nc2c1>>Nc1ccn2nc(-c3cccnc3)nc2c1 -US20150232480A1,6,COC(=O)[C@@H](OC(C)(C)C)c1c(C)c(-c2ccc(F)cc2)c2nc3cn2c1N1CCC(C)(CC1)OCCCC[C@H](C)Oc1ccc(F)cc1-c1cccc-3c1>>Cc1c([C@H](OC(C)(C)C)C(=O)O)c2n3cc(nc3c1-c1ccc(F)cc1)-c1cccc(c1)-c1cc(F)ccc1O[C@@H](C)CCCCOC1(C)CCN2CC1 -US20040192752A1,1,CCn1nc(C)c(C(=O)c2ccccc2)c1Cl.COc1ccc(O)cc1>>CCn1nc(C)c(C(=O)c2ccccc2)c1Oc1ccc(OC)cc1 -US05700819,6,COC(=O)Cc1cccc(Cc2nc3c(F)c(F)cc(F)c3s2)c1>>O=C(O)Cc1cccc(Cc2nc3c(F)c(F)cc(F)c3s2)c1 -US20090326229A1,3,Cc1cnc2[nH]c3c(OS(=O)(=O)C(F)(F)F)cccc3c2c1.OB(O)c1ccccc1>>Cc1cnc2[nH]c3c(-c4ccccc4)cccc3c2c1 -US08470816B2,1,CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1.N#Cc1cccnc1Cl>>CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(c2ncccc2C#N)C[C@H]1c1ccc(Cl)c(Cl)c1 -US04595745,2,Nc1ccccc1.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>O=C(Nc1ccccc1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 -US08217177B2,6,COc1cnc2ccc(CC(=O)OC(C)(C)C)cc2c1>>COc1cnc2ccc(CC(=O)O)cc2c1 -US06881846B2,2,CNC=O.O=C(Cl)C(Cl)Cl>>CN(C=O)C(=O)C(Cl)Cl -USRE039128E1,7,O=C(O)C12CCN(CC1)CC2>>OCC12CCN(CC1)CC2 -US06946478B2,2,CN(C)C(=O)COc1cc(Cl)ccc1C(=O)O.NCCN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1>>CN(C)C(=O)COc1cc(Cl)ccc1C(=O)NCCN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1 -USRE038761E1,3,COc1ccc(C=CC=O)cc1.N#CCC#N>>COc1ccc(C=CC=C(C#N)C#N)cc1 -US03994941,6,O=C1c2ccccc2C(=O)N1CCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>NCCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2 -US20100317657A1,3,CN(C)c1ncc(B2OC(C)(C)C(C)(C)O2)cn1.Cc1nn(C(C)C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>Cc1nn(C(C)C)cc1-n1c(=O)n(C)c2cnc3ccc(-c4cnc(N(C)C)nc4)cc3c21 -US20140206663A1,6,C[C@H]1CN(c2cc3c(cc2-c2ccccc2F)OCC2=NNC(=O)[C@@H](C)N23)[C@H](C)CN1C(=O)OC(C)(C)C>>C[C@H]1CN(c2cc3c(cc2-c2ccccc2F)OCC2=NNC(=O)[C@@H](C)N23)[C@H](C)CN1 -US05972975,9,Cc1cc(N)ncc1Br.N#C[Cu]>>Cc1cc(N)ncc1C#N -US06255323B1,6,O=C1c2ccccc2C(=O)N1CCN1CCC(NC(c2ccccc2)c2ccccc2)CC1>>NCCN1CCC(NC(c2ccccc2)c2ccccc2)CC1 -US20120220563A1,2,CCOc1noc(C2CNCC(c3ccc(CC(F)(F)F)cc3)C2)n1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCOc1noc(C2CC(c3ccc(CC(F)(F)F)cc3)CN(C(=O)Oc3ccc([N+](=O)[O-])cc3)C2)n1 -US20060247439A1,1,NC1CCC(Nc2ccc3ccccc3n2)CC1.O=Cc1ccsc1>>c1ccc2nc(NC3CCC(NCc4ccsc4)CC3)ccc2c1 -US20060241172A1,3,Cc1ccc(S(=O)(=O)OCC2Oc3cc(Cl)cc(Br)c3O2)cc1.OB(O)c1cc(F)ccc1F>>Cc1ccc(S(=O)(=O)OCC2Oc3cc(Cl)cc(-c4cc(F)ccc4F)c3O2)cc1 -US05134128,1,CC(=O)OC(CCCc1ccccc1)C1=CC(=O)OC1O.CO>>COC1OC(=O)C=C1C(CCCc1ccccc1)OC(C)=O -US20060154960A1,3,COc1ccc(-c2ccnn2-c2ccc(Br)cc2)cc1O[C@@H]1CCOC1.COc1ccc(B(O)O)cn1>>COc1ccc(-c2ccc(-n3nccc3-c3ccc(OC)c(O[C@@H]4CCOC4)c3)cc2)cn1 -US20070037807A1,6,Cc1ccc(-c2c(CNC(=O)OCc3ccccc3)c(CC(C)(C)C)nc(C)c2C(=O)O)cc1>>Cc1ccc(-c2c(CN)c(CC(C)(C)C)nc(C)c2C(=O)O)cc1 -US05635510,6,CC(C)(C)OC(=O)N1CCC(C#N)(c2cccs2)CC1>>N#CC1(c2cccs2)CCNCC1 -US05635534,1,COC(=O)Cc1cccc(OCC(C)=O)c1.NCC(O)c1cccc(Cl)c1>>COC(=O)Cc1cccc(OCC(C)NCC(O)c2cccc(Cl)c2)c1 -US20070049632A1,1,CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccccc3)c(=O)c12.CCBr>>CCn1c2c(c(=O)n1-c1ccccc1)[C@H]1CC[C@]2(C)C1(C)C -US20120220563A1,7,COC(=O)c1cncc(-c2ccc(OC(F)F)cc2)c1>>COC(=O)C1CNCC(c2ccc(OC(F)F)cc2)C1 -US20080269255A1,9,CCOC(=O)N1CC[C@](O)(c2cccc(-c3ccccc3)c2)[C@@H](O)C1>>CCOC(=O)N1CC[C@H](c2cccc(-c3ccccc3)c2)[C@@H](O)C1 -US05780503,1,COc1cc(C2CCC(O)O2)cc(OC)c1OC.O=C1c2ccccc2C(=O)N1CCCO>>COc1cc([C@H]2CC[C@@H](OCCCN3C(=O)c4ccccc4C3=O)O2)cc(OC)c1OC -US05747499,9,COC(=O)[C@H](CCC(N)=O)NC(=O)OCc1ccccc1>>COC(=O)[C@H](CCC#N)NC(=O)OCc1ccccc1 -US06187955B1,9,COCCOCCN.N#CN>>COCCOCCNC(=N)N -US20140051679A1,2,CN1CCC(Oc2ccc(-c3n[nH]c4ccc(N)cc34)cc2)CC1.Cc1cc(C)c(N=C=O)c(Cl)c1>>Cc1cc(C)c(NC(=O)Nc2ccc3[nH]nc(-c4ccc(OC5CCN(C)CC5)cc4)c3c2)c(Cl)c1 -US07781431B2,7,COC(=O)c1cc2[nH]c(-c3ccc(Cl)cc3)c(C3=CCCCC3)c2s1>>COC(=O)c1cc2[nH]c(-c3ccc(Cl)cc3)c(C3CCCCC3)c2s1 -US08580962B2,6,Cc1cccc(C#CC2=NOC3(CCN(C(=O)OC(C)(C)C)C3)C2)n1>>Cc1cccc(C#CC2=NOC3(CCNC3)C2)n1 -US07625901B2,2,N[C@@H]1c2ccccc2C[C@@H]1O.O=C(Cl)CCl>>O=C(CCl)N[C@@H]1c2ccccc2C[C@@H]1O -US20130274469A1,2,CC(C)(CN)CO.COC(=O)c1ccc(OCc2c(-c3ccc(F)c(F)c3)noc2C)nc1>>Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NCC(C)(C)CO)cn1 -US20110082129A1,3,CN1CCN(S(=O)(=O)Oc2cncc(Br)c2)CC1.Cn1c(B(O)O)cc2ccccc21>>CN1CCN(S(=O)(=O)Oc2cncc(-c3cc4ccccc4n3C)c2)CC1 -US06335353B1,1,BrCc1ccccc1.O=c1ccoc(CO)c1O>>O=c1ccoc(CO)c1OCc1ccccc1 -US08048879B2,2,CC(=O)c1ccc(N2CCN(C(=O)c3noc4c3CNCC4)CC2)cc1.Cc1ccc(S(=O)(=O)O)cc1>>CC(=O)c1ccc(N2CCN(C(=O)c3noc4c3CN(S(=O)(=O)c3ccc(C)cc3)CC4)CC2)cc1 -US20040214037A1,6,CCCCCCCCC1(CCCCCCCC)c2ccccc2-c2ccc(C#C[Si](C)(C)C)cc21>>C#Cc1ccc2c(c1)C(CCCCCCCC)(CCCCCCCC)c1ccccc1-2 -US20150239847A1,1,Fc1nccc(I)c1F.Nc1cc[nH]n1>>Nc1ccn(-c2nccc(I)c2F)n1 -US07279470B2,2,CC(C)(C)CC(=O)Nc1ccc(O)nc1.CN(C(=O)Cl)c1ccccc1>>CN(C(=O)Oc1ccc(NC(=O)CC(C)(C)C)cn1)c1ccccc1 -US20060217380A1,2,CN1CCNCC1.O=[N+]([O-])c1cc(C(F)(F)F)ccc1S(=O)(=O)Cl>>CN1CCN(S(=O)(=O)c2ccc(C(F)(F)F)cc2[N+](=O)[O-])CC1 -US20030162801A1,9,CC(=O)N1CCn2c1nc1c2c(=O)n(CCCC[C@@H](C)N=[N+]=[N-])c(=O)n1C>>CC(=O)N1CCn2c1nc1c2c(=O)n(CCCC[C@@H](C)N)c(=O)n1C -US06080885,2,C=C(C)C(=O)Cl.CCCC[P+](CCO)(CCCC)CCCC>>C=C(C)C(=O)OCC[P+](CCCC)(CCCC)CCCC -US20040214721A1,2,CCS(=O)(=O)N[C@H](C(=O)O)C(C)C.COc1cc(-c2ccccc2N)ccc1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CCS(=O)(=O)N[C@H](C(=O)Nc1ccccc1-c1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(OC)c1)C(C)C -US20060160794A1,2,CC(=O)Cl.O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCNCC1)N1CCC[C@@H]1c1ccccc1Cl>>CC(=O)N1CCN(c2c(C(=O)N3CCC[C@@H]3c3ccccc3Cl)nnn2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US20150119362A1,7,O=[N+]([O-])c1ccc(Cn2nccn2)cc1>>Nc1ccc(Cn2nccn2)cc1 -US20130045169A1,7,O=Cc1cccc(OCCCC2OCCO2)c1>>OCc1cccc(OCCCC2OCCO2)c1 -US20140088084A1,6,CC(C)(C)OC(=O)NC1=NC(CF)(c2cccc(NC(=O)c3ccc(Br)cn3)c2)COC1>>NC1=NC(CF)(c2cccc(NC(=O)c3ccc(Br)cn3)c2)COC1 -US06485797B1,7,CCCCCCCCC1Cc2c(F)cc(Br)cc2C1=O>>CCCCCCCCC1Cc2cc(Br)cc(F)c2C1 -US07368578B2,6,COCOc1nn(-c2ccccc2)cc1/C=C/c1nc(N2CCN(C(=O)OC(C)(C)C)CC2)sc1C>>Cc1sc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1/C=C/c1cn(-c2ccccc2)nc1O -US20110237607A1,9,Cn1cnc2c(NC3Cc4ccccc4C3)nc(Cl)nc21.NN>>Cn1cnc2c(NC3Cc4ccccc4C3)nc(NN)nc21 -US20060074102A1,6,CC(C)(C)OC(=O)CCNC(=O)c1cc2c(Nc3ccc(-c4ccccc4)cc3)cncc2s1>>O=C(O)CCNC(=O)c1cc2c(Nc3ccc(-c4ccccc4)cc3)cncc2s1 -US20110092461A1,1,Cc1nc(Cl)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.NCCCn1ccnc1>>Cc1nc(NCCCn2ccnc2)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1 -US20150011528A1,2,Cc1ccc(C(=O)Cl)cc1.Cc1ccc2nc(N)sc2c1>>Cc1ccc(C(=O)Nc2nc3ccc(C)cc3s2)cc1 -US20100121052A1,8,COc1cc(N)c(CO)cc1Br>>COc1cc(N)c(C=O)cc1Br -US07399863B2,1,CC(C)(C)[Si](C)(C)O[C@@H](CBr)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12.NCCc1ccc(NC[C@@H](O)c2ccccc2)cc1>>CC(C)(C)[Si](C)(C)O[C@@H](CNCCc1ccc(NC[C@@H](O)c2ccccc2)cc1)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12 -US04622415,6,CCOC(=O)C(C)Oc1cccc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)c1>>CC(Oc1cccc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)c1)C(=O)O -US20130225552A1,6,CC(C)(C)OC(=O)N1CCC(Nc2ncccc2[N+](=O)[O-])CC1>>O=[N+]([O-])c1cccnc1NC1CCNCC1 -US05153214,1,CCOC(=O)CSC(CCCCOS(C)(=O)=O)CCCc1cccnc1.[N-]=[N+]=[N-]>>CCOC(=O)CSC(CCCCN=[N+]=[N-])CCCc1cccnc1 -US20100256097A1,3,C#Cc1ccc(Cl)nc1C.CC(C)=O>>Cc1nc(Cl)ccc1C#CC(C)(C)O -US06906058B2,6,CCCCC1(CC)CN(c2ccccc2)c2cc(OCC(=O)OCC)ccc2S(=O)(=O)C1>>CCCCC1(CC)CN(c2ccccc2)c2cc(OCC(=O)O)ccc2S(=O)(=O)C1 -US20090318501A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCCOS(C)(=O)=O)c2cccc(Cl)c2)C1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCCN=[N+]=[N-])c2cccc(Cl)c2)C1 -US08431563B2,2,C[C@H]1CNCCN1c1ccc(C(C)(O)C(F)(F)F)cc1.O=S(=O)(Cl)c1ccoc1>>C[C@H]1CN(S(=O)(=O)c2ccoc2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1 -US04690931,1,CC(Br)C(=O)c1cccc(Cl)c1.c1ccc(CC2CCNCC2)cc1>>CC(C(=O)c1cccc(Cl)c1)N1CCC(Cc2ccccc2)CC1 -US06136810,7,CCn1c(=O)nc(-c2cccc(Cl)c2)c2ccc(C(C)OC(C)=O)nc21>>CCn1c(=O)nc(-c2cccc(Cl)c2)c2ccc(C(C)O)nc21 -US08455484B2,2,CC(=O)OC(C)=O.COCCNCc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)c(F)c4F)c3s2)nc1>>COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)c(F)c4F)c3s2)nc1)C(C)=O -US20100120798A1,7,CC1(C)CCN(c2cccc([N+](=O)[O-])c2)CC1>>CC1(C)CCN(c2cccc(N)c2)CC1 -US04710496,1,CC1CC(=O)NN=C1c1ccc(-n2ccc(C=O)c2)cc1.CNC>>CC1CC(=O)NN=C1c1ccc(-n2ccc(CN(C)C)c2)cc1 -US20070299130A1,1,C=CC(C)(C)O.COc1ccc(O)cc1>>C=CC(C)(C)Oc1ccc(OC)cc1 -US20090215742A1,6,CC(C)(C)OC(=O)N1Cc2ccccc2C1C(=O)NCC(F)(F)F>>O=C(NCC(F)(F)F)C1NCc2ccccc21 -US07858624B2,3,COCCCC[Mg+].CON(C)C(=O)C1CN(C(=O)OC(C)(C)C)CCO1>>COCCCCC(=O)C1CN(C(=O)OC(C)(C)C)CCO1 -US20070049607A1,10,Cc1cc([N+](=O)[O-])ccn1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1ccnc(CBr)c1 -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.CCOC(=O)c1csc(-c2cccc(Br)c2)n1>>CCOC(=O)c1csc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1 -US06495542B1,2,COC1C(=C=O)C(N2CCCCc3ccccc32)=CC=C1C(=O)O.Cc1nc2c(N)cccc2n1C(=O)OC(C)(C)C>>COC1C(=C=O)C(N2CCCCc3ccccc32)=CC=C1C(=O)Nc1cccc2c1nc(C)n2C(=O)OC(C)(C)C -US07868008B2,1,Cc1cc(CC2CCNCC2)cc2c1C(=O)N(CC1CC1)C2.O=Cc1cccc(F)c1>>Cc1cc(CC2CCN(Cc3cccc(F)c3)CC2)cc2c1C(=O)N(CC1CC1)C2 -US20080194647A1,1,Brc1cncc(C#Cc2ccccc2)c1.CC(C)(C)OC(N)=O>>CC(C)(C)OC(=O)Nc1cncc(C#Cc2ccccc2)c1 -US06300344B1,1,CI.COc1cccc2c1CCC2NCc1nc(-c2ccccc2)c(-c2ccccc2)o1>>COc1cccc2c1CCC2N(C)Cc1nc(-c2ccccc2)c(-c2ccccc2)o1 -US07160878B2,2,O=C(Cl)c1ccc(Cl)nn1.O=S(=O)(c1ccc2cc(Cl)ccc2c1)N1CCNCC1>>O=C(c1ccc(Cl)nn1)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1 -US07053086B2,3,CCOC(=O)c1c(C)[nH]c(C=O)c1CCC(=O)O.O=C1Cc2c(cccc2C2CCNCC2)N1>>CCOC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3cccc(C4CCNCC4)c32)c1CCC(=O)O -US20120270892A1,3,O=Cc1ccc(F)cc1Br.OB(O)c1ccco1>>O=Cc1ccc(F)cc1-c1ccco1 -US20130190290A1,9,O=C(O)c1cc(Br)cc(C(F)(F)F)c1.[C-]#N>>N#Cc1cc(C(=O)O)cc(C(F)(F)F)c1 -US20060004043A1,2,CCN.COc1ccc2cc(-c3nn(C4CCCCO4)c4ccc(C(=O)O)cc34)ccc2c1>>CCNC(=O)c1ccc2c(c1)c(-c1ccc3cc(OC)ccc3c1)nn2C1CCCCO1 -US20130267493A1,6,CC(C)(C)OC(=O)N1CCN(CCCOc2ccc(Br)cc2)CC1>>Brc1ccc(OCCCN2CCNCC2)cc1 -US20110027178A1,7,O=[N+]([O-])c1cccc2nc(Cl)ccc12>>Nc1cccc2nc(Cl)ccc12 -US20070142371A1,2,CCc1c(-c2cn(-c3cc(C(=O)OC)ccc3C)cn2)cnn1-c1ccccc1.COc1c(N)cc(C(C)(C)C)cc1C#N>>CCc1c(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)cc(C#N)c4OC)ccc3C)cn2)cnn1-c1ccccc1 -US20140191205A1,1,Brc1ccc2nc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)cc(-c3ccccc3)c2c1.c1ccc2c(c1)[nH]c1ccccc12>>c1ccc(-c2cc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)nc3ccc(-n4c5ccccc5c5ccccc54)cc23)cc1 -US20150191466A1,6,COc1ccc(COc2ccc(Cn3cnc4cc(N5CC6(CCN(C(=O)OC(C)(C)C)CC6)C5)ccc43)cc2OC)cn1>>COc1ccc(COc2ccc(Cn3cnc4cc(N5CC6(CCNCC6)C5)ccc43)cc2OC)cn1 -US08415345B2,2,CO.O=C(O)c1cccc(Br)c1F>>COC(=O)c1cccc(Br)c1F -US20150087823A1,2,CCCCCCC/C=C/C(=O)O.CCOC(=O)COc1ccc(N2CCNCC2)cc1>>CCCCCCC/C=C/C(=O)N1CCN(c2ccc(OCC(=O)OCC)cc2)CC1 -US20140066455A1,2,CCOC(=O)c1ccc(N2CCN(CC)CC2)s1.COc1cc(COc2cc(N)[nH]n2)cc(OC)c1>>CCN1CCN(c2ccc(C(=O)Nc3cc(OCc4cc(OC)cc(OC)c4)n[nH]3)s2)CC1 -US20050065189A1,2,CCCCCc1sc(C(=O)O)nc1-c1ccccc1.Nc1ccccc1>>CCCCCc1sc(C(=O)Nc2ccccc2)nc1-c1ccccc1 -US20120101136A1,6,CCOC(=O)CCCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c(CC)c1>>CCc1cc(OCCCCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 -US20060089349A1,2,CNc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1.O=C(Cl)CCl>>CN(C(=O)CCl)c1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1 -US20090197959A1,2,CCNCc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)ccc1OC.COCC(=O)Cl>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)ccc1OC)C(=O)COC -US20100075978A1,2,N[C@@H]1CC[C@@H](CCN2CCCC2)CC1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccc(Cl)cc2Cl)cc1>>O=C(N[C@@H]1CC[C@@H](CCN2CCCC2)CC1)c1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccc(Cl)cc2Cl)cc1 -US20080261941A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1cccc(OCc2ccccc2)c1)OCC>>CC(C)(C)OC(=O)N1CCC(=Cc2cccc(OCc3ccccc3)c2)CC1 -US20080033049A1,9,NO.O=Cc1ccc(-c2ccc(O)cc2)cc1F>>ON=Cc1ccc(-c2ccc(O)cc2)cc1F -US20100130538A1,3,CC(=O)NCC1CC1c1c(Br)ccc2nn(C)cc12.OB(O)C1CC1>>CC(=O)NCC1CC1c1c(C2CC2)ccc2nn(C)cc12 -US05488055,8,CCn1ncc2c(Cl)c3cc(SC)ccc3nc21.O=C(OO)c1cccc(Cl)c1>>CCn1ncc2c(Cl)c3cc(S(C)=O)ccc3nc21 -US20080261941A1,2,CCOC(=O)Nc1cccnn1.FC(F)(F)c1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1>>O=C(Nc1cccnn1)N1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1 -US06329405B1,1,CC(N)c1cc(F)cc(F)c1.O=C(c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1>>CC(NC(c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1)c1cc(F)cc(F)c1 -US06936611B2,6,CC(C)(C)OC(=O)N1CCN(CCc2ccncc2F)CC1>>Fc1cnccc1CCN1CCNCC1 -US20130045986A1,6,CC(C)(C)OC(=O)N1CCC(c2ccc3nc(-c4ccc(S(C)(=O)=O)cc4F)oc3c2)CC1>>CS(=O)(=O)c1ccc(-c2nc3ccc(C4CCNCC4)cc3o2)c(F)c1 -US07956188B2,2,CC(C)(C)N.CSC(Oc1cc(C)c(Br)c(C)c1)C(=O)O>>CSC(Oc1cc(C)c(Br)c(C)c1)C(=O)NC(C)(C)C -US20120309739A1,1,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4c(Br)c[nH]c(=O)c4c3-c3ccccc3)cc2)CCC1.FCCI>>CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4c(Br)cn(CCF)c(=O)c4c3-c3ccccc3)cc2)CCC1 -US20130109682A1,6,COC(=O)c1ccc(F)c(-c2c(F)ccc(C(=O)N(C)C)c2F)n1>>CN(C)C(=O)c1ccc(F)c(-c2nc(C(=O)O)ccc2F)c1F -US05071851,4,CC(C)(C1CCCCC1)C1CCC(N)CC1.CC(CCl)OC(C)CCl>>CC1CN(C2CCC(C(C)(C)C3CCCCC3)CC2)CC(C)O1 -US08143290B2,2,COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)N)c1.O=C(O)c1ccc(Br)s1>>COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)NC(=O)c2ccc(Br)s2)c1 -US20110009454A1,2,Cc1ccc(C(=O)O)c(Cl)n1.Cc1cccc(Oc2ccc(CN)cc2)c1>>Cc1cccc(Oc2ccc(CNC(=O)c3ccc(C)nc3Cl)cc2)c1 -US20100069582A1,3,C=CCCCBr.[Mg+]C1=CC=CC1>>C=CCCCC1=CC=CC1 -US07674801B2,3,CCNC(=O)Nc1cc(-c2nc(-c3ccccc3)cs2)c(Br)cn1.CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1cc(-c2nc(-c3ccccc3)cs2)c(-c2cncc(C(=O)OCC)c2)cn1 -US05134142,2,CS(=O)(=O)Cl.CS(=O)(=O)c1ccc(-c2cc(N)nn2-c2ccc(F)cc2)cc1>>CS(=O)(=O)Nc1cc(-c2ccc(S(C)(=O)=O)cc2)n(-c2ccc(F)cc2)n1 -US20060293352A1,1,COc1ccc(F)cc1S.CS(=O)(=O)c1ccc(F)c(Cl)c1>>COc1ccc(F)cc1Sc1ccc(S(C)(=O)=O)cc1Cl -US20060004084A1,2,CCN(CC)CCN.O=C1Nc2ccccc2C1=C1OCc2cc(C(=O)O)ccc21>>CCN(CC)CCNC(=O)c1ccc2c(c1)COC2=C1C(=O)Nc2ccccc21 -US20070259965A1,2,NCC(O)CN.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>NCC(O)CNS(=O)(=O)c1ccc(Cl)cc1Cl -US20140005382A1,3,CC(C)(CO[Si](C)(C)C(C)(C)C)c1ccc(Br)cc1.CN(C)C=O>>CC(C)(CO[Si](C)(C)C(C)(C)C)c1ccc(C=O)cc1 -US20130040930A1,6,Cc1ccc(N2CCN(C(=O)c3ccc(N(CCOC4CCCCO4)S(C)(=O)=O)cc3)CC2)c(C)c1>>Cc1ccc(N2CCN(C(=O)c3ccc(N(CCO)S(C)(=O)=O)cc3)CC2)c(C)c1 -US06300342B1,1,N#Cc1ccc(CCC(=O)N2CCCc3cc(N)ccc32)cc1.O=Cc1ccccc1>>N#Cc1ccc(CCC(=O)N2CCCc3cc(NCc4ccccc4)ccc32)cc1 -US06620815B1,1,C1CNCCN1.N#CC1(c2ccccc2)CCC(=O)CC1>>N#CC1(c2ccccc2)CCC(N2CCNCC2)CC1 -US20070149521A1,3,CC(C)(C)Sc1nc(Br)c2c(N)nccn12.CC1(C)OB(c2ccc3ccc(-c4ccccc4)nc3c2F)OC1(C)C>>CC(C)(C)Sc1nc(-c2ccc3ccc(-c4ccccc4)nc3c2F)c2c(N)nccn12 -US20040157891A1,1,COc1ccc(-c2nc(Cl)oc2-c2ccc(OC)cc2)cc1.C[O-]>>COc1ccc(-c2nc(OC)oc2-c2ccc(OC)cc2)cc1 -US20140336377A1,2,Cc1cc(C(=O)O)nc(Nc2ncco2)n1.NCc1ccc(OCC(F)(F)F)nc1>>Cc1cc(C(=O)NCc2ccc(OCC(F)(F)F)nc2)nc(Nc2ncco2)n1 -US08314126B2,1,CC(=O)c1cccc(C2CCNCC2)c1F.COCCBr>>COCCN1CCC(c2cccc(C(C)=O)c2F)CC1 -US20070244173A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc2c([nH]1)CCCC2=O>>Cc1nc2c(n1C(=O)OC(C)(C)C)CCCC2=O -US20100016337A1,2,C1CCNCC1.O=C(O)COc1ccc(Br)nn1>>O=C(COc1ccc(Br)nn1)N1CCCCC1 -US20100016360A1,2,C=C(C)OC(=O)Cl.Nc1ccc(Br)nc1>>C=C(C)OC(=O)Nc1ccc(Br)nc1 -US05872118,7,O=C(O)C=Cc1ccc(F)cc1F>>O=C(O)CCc1ccc(F)cc1F -US20150232459A1,6,COC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H](C(=O)N(C2CC2)[C@H](C)c2cc(CCCNC(=O)OC)nc(OC)c2)O1>>COC[C@@H]1CNC[C@H](C(=O)N(C2CC2)[C@H](C)c2cc(CCCNC(=O)OC)nc(OC)c2)O1 -US20110092505A1,3,CC(C)(C)OC(=O)N1CCN(c2ccc(Br)c(-c3ccnc(Cl)c3)n2)CC1.OB(O)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3ccc(F)cc3)c(-c3ccnc(Cl)c3)n2)CC1 -US08173650B2,1,C1CC(C2CNC2)CCO1.Cn1c(C=O)nc2c(N3CCOCC3)nc(Cl)nc21>>Cn1c(CN2CC(C3CCOCC3)C2)nc2c(N3CCOCC3)nc(Cl)nc21 -US20050153970A1,1,CCCN.O=CCCc1ccc(F)cc1>>CCCNCCCc1ccc(F)cc1 -US07132436B2,2,Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Cl.Nc1nc(-c2ccc(Cl)s2)cs1>>Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Nc1nc(-c2ccc(Cl)s2)cs1 -US05436240,4,COc1ccc(N)c(N)c1C.O=CO>>COc1ccc2[nH]cnc2c1C -US20100136136A1,7,CN1CCN(CCCOc2ccc(N)c([N+](=O)[O-])c2)CC1>>CN1CCN(CCCOc2ccc(N)c(N)c2)CC1 -US05883133,1,CCOC(=O)/C(C)=C/c1ccc(F)c(C(F)(F)F)c1.Oc1cccnc1>>CCOC(=O)/C(C)=C/c1ccc(Oc2cccnc2)c(C(F)(F)F)c1 -US05134152,1,CC(OS(C)(=O)=O)C(C)(C)C(O)(Cn1cncn1)c1ccc(F)cc1F>>CC1OC(Cn2cncn2)(c2ccc(F)cc2F)C1(C)C -US20140142029A1,6,C[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)C>>C[C@H](N)C(=O)N(C)C -US08592579B2,1,CC(C)Br.O=[N+]([O-])c1c[nH]cn1>>CC(C)n1cnc([N+](=O)[O-])c1 -US06080750,9,Nc1nc(Cl)cc(NCC2(CO)CCC2)n1>>Nc1nccc(NCC2(CO)CCC2)n1 -US08093239B2,1,CC(C)Oc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F.CCOc1cc(N2CCN(CCS(C)(=O)=O)CC2)c(C)cc1N>>CCOc1cc(N2CCN(CCS(C)(=O)=O)CC2)c(C)cc1Nc1nccc(-c2c(-c3ccc(OC(C)C)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US08877780B2,7,N#Cc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O>>NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O -US04831027,7,CC1(C)OC(=O)Nc2cc([N+](=O)[O-])c(N)cc21>>CC1(C)OC(=O)Nc2cc(N)c(N)cc21 -US20110124597A1,1,BrCCCBr.O=Cc1cccc(O)c1Br>>O=Cc1cccc(OCCCBr)c1Br -US20100197711A1,1,NNc1nc2ccccc2s1.O=C(O)c1coc(-c2ccc3c(c2)C(=O)CCC3)n1>>O=C(O)c1coc(-c2ccc3c(c2)C(=NNc2nc4ccccc4s2)CCC3)n1 -US20110046169A1,1,O=C(Nc1cn2cc(O)ccc2n1)C1CC1.O=[N+]([O-])c1ccc(Cl)nc1>>O=C(Nc1cn2cc(Oc3ccc([N+](=O)[O-])cn3)ccc2n1)C1CC1 -US05935966,9,CCOC(=O)c1cnc(Cl)nc1C(F)(F)C(F)(F)F.NN>>CCOC(=O)c1cnc(NN)nc1C(F)(F)C(F)(F)F -US04889857,1,CNCCC1CNCCO1.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>CNCCC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CCO1 -US09156834B2,2,Fc1ccc2nc(N3CCNCC3)oc2c1.O=C(O)c1ccc(NS(=O)(=O)c2ccccn2)cc1>>O=C(c1ccc(NS(=O)(=O)c2ccccn2)cc1)N1CCN(c2nc3ccc(F)cc3o2)CC1 -US20090253687A1,4,NNc1cccc(C(F)(F)F)c1.O=C1COc2ccc(C(=O)CC(=O)C(F)(F)F)cc2N1>>O=C1COc2ccc(-c3cc(C(F)(F)F)nn3-c3cccc(C(F)(F)F)c3)cc2N1 -US08946697B1,3,Cc1ccc2c(n1)oc1c(B3OC(C)(C)C(C)(C)O3)cccc12.Fc1cccc(-c2ccnc(Cl)c2)c1F>>Cc1ccc2c(n1)oc1c(-c3cc(-c4cccc(F)c4F)ccn3)cccc12 -US08153805B2,2,Cc1nc(-c2cccc(C(F)(F)F)c2)nc(C)c1C(=O)O.O=C(OC[C@@H]1CCCN1C1CCNCC1)c1ccccc1>>Cc1nc(-c2cccc(C(F)(F)F)c2)nc(C)c1C(=O)N1CCC(N2CCC[C@H]2COC(=O)c2ccccc2)CC1 -US06969725B2,6,CCO[C@@H](Cc1ccc(OCc2nc(-c3ccccc3F)oc2C)cc1F)C(=O)OC>>CCO[C@@H](Cc1ccc(OCc2nc(-c3ccccc3F)oc2C)cc1F)C(=O)O -US20130172292A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1c(Oc2ccc(Br)cc2)nc2cccnc21>>Cn1c(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)nc2cccnc21 -US20090012063A1,3,Cn1c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)nc(I)c1C(=O)N1CCC(N2CCCC2)CC1.OB(O)c1ccncc1>>Cn1c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)nc(-c2ccncc2)c1C(=O)N1CCC(N2CCCC2)CC1 -US08138175B2,6,C[C@H]1C(=O)N(CCCN2CCC3(CC3)[C@H](O[Si](C)(C)C(C)(C)C)C2)CCN1c1ccc(Cl)c(OC(F)(F)F)c1>>C[C@H]1C(=O)N(CCCN2CCC3(CC3)[C@H](O)C2)CCN1c1ccc(Cl)c(OC(F)(F)F)c1 -US20140249131A1,8,CSc1ncc(CO)c(Nc2cccc(NC(=O)OC(C)(C)C)c2)n1>>CSc1ncc(C=O)c(Nc2cccc(NC(=O)OC(C)(C)C)c2)n1 -US20020137755A1,2,CN=C=O.O=C(OCc1ccccc1)N1CCN(C2CCNC2)CC1>>CNC(=O)N1CCC(N2CCN(C(=O)OCc3ccccc3)CC2)C1 -US07199244B2,6,C=C(CNC(=O)OC(C)(C)C)c1ccc2c(c1)CCCC2NC(=O)CC1CCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1>>C=C(CN)c1ccc2c(c1)CCCC2NC(=O)CC1CCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1 -US07825238B2,1,COc1ccc(COC(=O)c2ccc(O)cc2)cc1.OCCBr>>COc1ccc(COC(=O)c2ccc(OCCO)cc2)cc1 -US20140073650A1,1,CCOC(=O)CBr.Oc1ccc2cc(Br)ccc2c1>>CCOC(=O)COc1ccc2cc(Br)ccc2c1 -US20090042841A1,1,Cc1cccc(C#CC=C2CCNCC2)n1.O=C(Nc1ccccc1)c1ccc(Br)o1>>Cc1cccc(C#CC=C2CCN(c3ccc(C(=O)Nc4ccccc4)o3)CC2)n1 -US20090253684A1,6,COc1cc(I)cc(C(=O)NCc2ccccc2)c1>>O=C(NCc1ccccc1)c1cc(O)cc(I)c1 -US20090227566A1,6,COCOc1cc(C(C)N)ccc1C(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1>>CC(N)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)c(O)c1 -US07378417B2,2,Cc1ccc(S(N)(=O)=O)cc1N.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>Cc1ccc(S(N)(=O)=O)cc1NC(=O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12 -US20040023958A1,6,O=C(CCc1ccc(OCc2ccccc2)cc1)C1CCCC1>>O=C(CCc1ccc(O)cc1)C1CCCC1 -US20040167154A1,2,CCCCCCc1nc2cnc3ccccc3c2n1CCCCN.O=C=Nc1ccccc1>>CCCCCCc1nc2cnc3ccccc3c2n1CCCCNC(=O)Nc1ccccc1 -US20110098352A1,3,CCOC(=O)Cc1ccc(OCc2ccccc2)c(B2OC(C)(C)C(C)(C)O2)c1.O=Cc1cc(C(F)(F)F)ccc1Br>>CCOC(=O)Cc1ccc(OCc2ccccc2)c(-c2ccc(C(F)(F)F)cc2C=O)c1 -US20130190338A1,2,COC(=O)c1ccccc1CSc1ccccc1N.O=S(=O)(Cl)c1cc2ccccc2o1>>COC(=O)c1ccccc1CSc1ccccc1NS(=O)(=O)c1cc2ccccc2o1 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1cc(-c2ccc(O)cc2)ccc1F>>Oc1ccc(-c2ccc(F)c(CNc3cccc(-c4c(Cc5ccccc5)cnc5c(C(F)(F)F)cccc45)c3)c2)cc1 -US20080004274A1,1,CCCN1C(=O)C(=O)c2cc(SCCCc3ccc(C(=O)O)cc3)ccc21.NNC(N)=O>>CCCN1C(=O)C(=NNC(N)=O)c2cc(SCCCc3ccc(C(=O)O)cc3)ccc21 -US20090227566A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccccc2[N+](=O)[O-])CC1 -US20140228361A1,6,COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CC2CCN(C(=O)OC(C)(C)C)CC2C1>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CC2CCNCC2C1 -US05716964,10,Cc1nc(N2C(=O)c3ccccc3C2=O)ccc1Cl.O=C1CCC(=O)N1Br>>O=C1c2ccccc2C(=O)N1c1ccc(Cl)c(CBr)n1 -US08030332B2,1,Clc1cccnc1Cl.c1ccc2c(c1)NCCO2>>Clc1cccnc1N1CCOc2ccccc21 -US04066635,9,COC(=O)CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1.N>>NC(=O)CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1 -US07247633B2,1,C[C@H]1CN[C@H](C)CN1.Clc1cncc(Cl)n1>>C[C@H]1CN[C@H](C)CN1c1cncc(Cl)n1 -US06448442B1,7,O=C(NCC(O)CO)c1cc(C(O)CO)cc([N+](=O)[O-])c1>>Nc1cc(C(=O)NCC(O)CO)cc(C(O)CO)c1 -US05948812,1,BrCCCCCCBr.CC(CCO)CCO>>CC(CCO)CCOCCCCCCBr -US06720334B2,6,Cc1nc(Oc2ccccc2)c2nc(C)n(CCCCNC(=O)OC(C)(C)C)c2c1C>>Cc1nc(Oc2ccccc2)c2nc(C)n(CCCCN)c2c1C -US20120328691A1,1,CC1CN(C(=O)OC(C)(C)C)CCN1.O=[N+]([O-])c1ccccc1Br>>CC1CN(C(=O)OC(C)(C)C)CCN1c1ccccc1[N+](=O)[O-] -US20090136448A1,5,COC(=O)c1sccc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1sccc1NC(=O)C(F)(F)F -US20100009969A1,6,C[C@@H]1CCCN1CCCOc1ccc(-c2nc3c(s2)CN(CC(=O)OC(C)(C)C)CC3)cc1>>C[C@@H]1CCCN1CCCOc1ccc(-c2nc3c(s2)CN(CC(=O)O)CC3)cc1 -US06180791B2,1,C1CCNC1.O=c1c2[nH]c(Cl)nc2n(CC2CC2)c(=O)n1CC1CC1>>O=c1c2[nH]c(N3CCCC3)nc2n(CC2CC2)c(=O)n1CC1CC1 -US05534515,7,Cc1c(C=O)c2cnnc(OCc3ccc(F)cc3)c2n1Cc1ccccc1>>Cc1c(CO)c2cnnc(OCc3ccc(F)cc3)c2n1Cc1ccccc1 -US07973185B2,6,COc1ccccc1C(=O)O>>O=C(O)c1ccccc1O -US04197243,2,CCN(CC)c1cc(OC)c(C(=O)O)cc1Cl.NC1CCN(Cc2ccccc2)C1>>CCN(CC)c1cc(OC)c(C(=O)NC2CCN(Cc3ccccc3)C2)cc1Cl -US20030199473A1,9,N#Cc1ccc(Nc2nc(Cl)nc(Cc3c(Cl)cccc3Cl)n2)cc1.[N-]=[N+]=[N-]>>N#Cc1ccc(Nc2nc(Cc3c(Cl)cccc3Cl)nc(N=[N+]=[N-])n2)cc1 -US20110288084A1,1,COc1ccc2ncc(=O)n(CC(NS(=O)(=O)c3ccccc3[N+](=O)[O-])[C@@H]3CC[C@@H](N)CC3)c2c1.O=Cc1ccc2c(n1)NC(=O)CO2>>COc1ccc2ncc(=O)n(CC(NS(=O)(=O)c3ccccc3[N+](=O)[O-])[C@@H]3CC[C@@H](NCc4ccc5c(n4)NC(=O)CO5)CC3)c2c1 -US20070173486A1,6,Clc1ccc(C(OC2CCN(Cc3ccccc3)CC2)c2ccc(Cl)cc2Cl)cc1>>Clc1ccc(C(OC2CCNCC2)c2ccc(Cl)cc2Cl)cc1 -US04001234,1,CN(C)C(=O)Nc1ccc(O)cc1.Cc1cc(Cl)nc(Cl)n1>>Cc1cc(Oc2ccc(NC(=O)N(C)C)cc2)nc(Cl)n1 -US04470988,1,CCOC(=O)CBr.O=C1Nc2ccccc2CCCC1N1C(=O)c2ccccc2C1=O>>CCOC(=O)CN1C(=O)C(N2C(=O)c3ccccc3C2=O)CCCc2ccccc21 -US20050014765A1,2,COc1cc(OC)cc(N2CCNCC2)c1.Nc1nc(-c2ccccc2)c(C(=O)O)s1>>COc1cc(OC)cc(N2CCN(C(=O)c3sc(N)nc3-c3ccccc3)CC2)c1 -US20050075326A1,1,CC(C)(C)OC(=O)NC(CC=O)c1ccccc1.O=C1N(Cc2ccc(Br)cc2)CCC12CCNCC2>>CC(C)(C)OC(=O)NC(CCN1CCC2(CC1)CCN(Cc1ccc(Br)cc1)C2=O)c1ccccc1 -US20060034796A1,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1.O=C(NCCO)OCC1c2ccccc2-c2ccccc21>>O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)OCC1c2ccccc2-c2ccccc21 -US20080045530A1,2,C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1.O=C(O)[C@H]1CN(Cc2cccc3ccccc23)C[C@@H]1Cc1ccc(Cl)cc1>>C=C[C@@H]1C[C@]1(NC(=O)[C@H]1CN(Cc2cccc3ccccc23)C[C@@H]1Cc1ccc(Cl)cc1)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1 -US08642585B2,1,CI.Cc1cc(OC2CCS(=O)(=O)NC2)cc(C)c1Br>>Cc1cc(OC2CCS(=O)(=O)N(C)C2)cc(C)c1Br -US20090029905A1,2,C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(Oc2ncc(C(=O)N3CCC3)cc2Cl)cc(C(=O)O)c1.Cc1cnc(N)cn1>>Cc1cnc(NC(=O)c2cc(Oc3ncc(C(=O)N4CCC4)cc3Cl)cc(O[C@@H](C)CO[Si](C)(C)C(C)(C)C)c2)cn1 -US20100144747A1,3,CCCC[Sn](CCCC)(CCCC)c1ccnn1C(C)C.COC(=O)c1cc(I)c(C(C)F)cc1N>>COC(=O)c1cc(-c2ccnn2C(C)C)c(C(C)F)cc1N -US20080096922A1,1,COc1cccc(C2(C(=O)NS(=O)(=O)Oc3c(C(C)C)cccc3C(C)C)CCC(=O)CC2)c1.Nc1ccccc1>>COc1cccc(C2(C(=O)NS(=O)(=O)Oc3c(C(C)C)cccc3C(C)C)CCC(Nc3ccccc3)CC2)c1 -US08367824B2,1,COC(=O)c1ccc(O)c(OC)c1.ClCCCBr>>COC(=O)c1ccc(OCCCCl)c(OC)c1 -US20130324501A1,6,CCOC(=O)c1cc(N(C(=O)OC(C)(C)C)S(C)(=O)=O)cs1>>CC(C)(C)OC(=O)N(c1csc(C(=O)O)c1)S(C)(=O)=O -US20110092554A1,1,COC(=O)Cc1cc(O)cc(O)c1.ClCc1ccccc1>>COC(=O)Cc1cc(O)cc(OCc2ccccc2)c1 -US20060122197A1,2,Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@H](N)C1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@H](NC(=O)Oc2ccc([N+](=O)[O-])cc2)C1 -US20130225524A1,1,COC(=O)c1cc(N)cc(-c2ccccc2)c1.COc1ncc(-c2ccc3c(Cl)c(C(N)=O)cnc3c2)c(OC)n1>>COC(=O)c1cc(Nc2c(C(N)=O)cnc3cc(-c4cnc(OC)nc4OC)ccc23)cc(-c2ccccc2)c1 -US07332510B2,1,Cc1nc(C#Cc2ccnc(C#N)c2)c[nH]1.OB(O)c1ccc(Cl)nc1>>Cc1nc(C#Cc2ccnc(C#N)c2)cn1-c1ccc(Cl)nc1 -US20120245161A1,2,COCCn1cc(C(=O)O)c2cccc(C(F)F)c21.O=C(NCc1ccc(F)c(C2CCNCC2)c1)C(F)(F)F>>COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)C(F)(F)F)ccc3F)CC2)c2cccc(C(F)F)c21 -US08293902B2,1,COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1O.OCCCBr>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCBr -US20100286114A1,6,CCOC(=O)c1cc(N2CCN(CCN(C)C)CC2)ccc1Cl>>CN(C)CCN1CCN(c2ccc(Cl)c(C(=O)O)c2)CC1 -US08173650B2,1,CN(C)C1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1.c1ccc2[nH]cnc2c1>>CN(C)C1CCN(Cc2cc3nc(-n4cnc5ccccc54)nc(N4CCOCC4)c3s2)CC1 -US20040236110A1,1,Brc1ccc2[nH]ccc2c1.Fc1ccccn1>>Brc1ccc2c(ccn2-c2ccccn2)c1 -US06326397B1,1,CC(C)(C)c1cc(Br)c(O)c(C(C)(C)C)c1.CCI>>CCOc1c(Br)cc(C(C)(C)C)cc1C(C)(C)C -US05646313,2,CC(C)(C)C(=O)SC/C(=C/c1ccccc1)C(=O)O.NCCC(=O)OCc1ccccc1>>CC(C)(C)C(=O)SC/C(=C/c1ccccc1)C(=O)NCCC(=O)OCc1ccccc1 -US08026255B2,1,CCOc1cc(CN2CCC(N)CC2)ccc1OC.Fc1ccc2nc(Cl)ccc2c1>>CCOc1cc(CN2CCC(Nc3ccc4cc(F)ccc4n3)CC2)ccc1OC -US20100305207A1,2,COCCOc1ccc(C(=O)N[C@H](C(=O)OC)[C@@H](C)OC(C)(C)C)c(N)c1.Cc1cc(CC2CC2)cc(C)c1N=C=O>>COCCOc1ccc(C(=O)N[C@H](C(=O)OC)[C@@H](C)OC(C)(C)C)c(NC(=O)Nc2c(C)cc(CC3CC3)cc2C)c1 -US06331563B1,6,CCOC(=O)C(C)(CCCCN1C(=O)c2ccccc2C1=O)S(=O)(=O)c1ccc(OC)cc1>>COc1ccc(S(=O)(=O)C(C)(CCCCN2C(=O)c3ccccc3C2=O)C(=O)O)cc1 -US20130324579A1,1,COc1ccc2c(c1)CCN2.O=CCCn1cc([N+](=O)[O-])cn1>>COc1ccc2c(c1)CCN2CCCn1cc([N+](=O)[O-])cn1 -US20040171634A1,2,CC(=O)OC(C)=O.CN(c1cccc(N)c1)c1ccc2c(C=Cc3ccccc3)n[nH]c2c1>>CC(=O)Nc1cccc(N(C)c2ccc3c(C=Cc4ccccc4)n[nH]c3c2)c1 -US20100311749A1,2,Cc1ccc(N2CCOCC2)cc1N1CCNCC1=O.O=C(Cl)c1cccc(C(F)(F)F)c1Cl>>Cc1ccc(N2CCOCC2)cc1N1CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)CC1=O -US20100311715A1,2,CC(=O)OC(C)=O.NCCn1c2ccccc2c2cc(C(N)=O)c(N)nc21>>CC(=O)NCCn1c2ccccc2c2cc(C(N)=O)c(N)nc21 -US20070135367A1,2,Nc1cc(F)ccc1N1CCCCC1.O=C(Cl)c1ccncc1>>O=C(Nc1cc(F)ccc1N1CCCCC1)c1ccncc1 -US05952266,5,Cc1cc(Br)c(C)c2c1SCCC2=O.OCCO>>Cc1cc(Br)c(C)c2c1SCCC21OCCO1 -US07902252B2,6,COC(=O)c1cc2c([nH]1)CCC2Cc1cc(C)cc(C)c1>>Cc1cc(C)cc(CC2CCc3[nH]c(C(=O)O)cc32)c1 -US06235731B1,2,CS(=O)(=O)Cl.OC[C@@H]1COc2ccccc2O1>>CS(=O)(=O)OC[C@@H]1COc2ccccc2O1 -US07589232B2,1,CCCCCCCCC#Cc1ccc(C=O)cc1.COC(=O)COc1ccc(CN)cc1>>CCCCCCCCC#Cc1ccc(CNCc2ccc(OCC(=O)OC)cc2)cc1 -US03985896,1,BrCCCBr.O=C1c2c(oc3ccccc23)-c2ccc(O)c3cccc1c23>>O=C1c2c(oc3ccccc23)-c2ccc(OCCCBr)c3cccc1c23 -US20020193578A1,6,CCOC1(c2ccc(C#Cc3ccc(CC(=O)OC)cc3)cc2C(C)(C)C)CC1>>CCOC1(c2ccc(C#Cc3ccc(CC(=O)O)cc3)cc2C(C)(C)C)CC1 -US09126981B2,1,CCOC(OCC)[C@H](C)N.O=Cc1csc2ccc(Cl)nc12>>CCOC(OCC)[C@H](C)NCc1csc2ccc(Cl)nc12 -US06348480B1,2,CCOC(=O)c1cnn(-c2ccc(N)cc2)c1C(F)(F)F.CS(=O)(=O)Cl>>CCOC(=O)c1cnn(-c2ccc(NS(C)(=O)=O)cc2)c1C(F)(F)F -US20060160820A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)Cc2cccnc2)CC1>>O=C(Cc1cccnc1)N1CCNCC1 -US20120322788A1,1,Cc1nc(C(=O)N2CCOC3(CCNCC3)C2)cs1.O=Cc1cccc(CBr)c1>>Cc1nc(C(=O)N2CCOC3(CCN(Cc4cccc(C=O)c4)CC3)C2)cs1 -US20100267666A1,3,CC1(C(=O)c2c[nH]c3ncc(Br)nc23)CCCC1.COc1cc(B(O)O)cc(OC)c1OC>>COc1cc(-c2cnc3[nH]cc(C(=O)C4(C)CCCC4)c3n2)cc(OC)c1OC -US20130116231A1,6,CC(C)(C)OC(=O)c1nn(-c2cccc(Br)c2)ccc1=O>>O=C(O)c1nn(-c2cccc(Br)c2)ccc1=O -US07625901B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC[C@H]1OC[C@@H](c2ccccc2)NC1=O>>CC[C@H]1OC[C@@H](c2ccccc2)N(C(=O)OC(C)(C)C)C1=O -US20140364412A1,1,CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCC[C@@H]5C)n4c3)c3ccccc32)cc1CCl)(C(C)C)C(C)C.CN1CCNCC1>>CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCC[C@@H]5C)n4c3)c3ccccc32)cc1CN1CCN(C)CC1)(C(C)C)C(C)C -US04278808,7,CCC(=COCCBr)C(=O)OC>>CCC(COCCBr)C(=O)OC -US20080318943A1,1,CCCC[Sn](Cl)(CCCC)CCCC.COc1ccc(F)cn1>>CCCC[Sn](CCCC)(CCCC)c1cc(OC)ncc1F -US20080027070A1,7,O=C(Nc1ccc(Cl)c(C(=O)O)c1)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c(CO)c1)c1cccc(C(F)(F)F)c1 -US20090163488A1,2,Cc1cc(C(=O)Nc2cccc(Oc3ccc(N)nc3)c2)n(C)n1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc(Oc3cccc(NC(=O)c4cc(C)nn4C)c3)cn2)cc1 -US20090192145A1,2,CS(=O)(=O)Cl.N#Cc1ccc2c(c1)CCCC2(SCCO)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CS(=O)(=O)OCCSC1(c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)CCCc2cc(C#N)ccc21 -US04350638,6,CCOC(=O)C=C(C)C(C)C>>CC(=CC(=O)O)C(C)C -US07999006B2,2,C=CCNC(=O)C1(O)CNC1.O=C(O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F>>C=CCNC(=O)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US20100144724A1,3,Brc1cccc(CN2CCCCC2)n1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2cccc(CN3CCCCC3)n2)cc1 -US20130324576A1,6,CC(C)(C)OC(=O)N1CCC(C(C#N)c2ccc(Cl)cc2)CC1>>N#CC(c1ccc(Cl)cc1)C1CCNCC1 -US20140275085A1,3,COc1nc(SC)ncc1-c1ccc(Oc2ccnc(Cl)c2)c(C)n1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COc1nc(SC)ncc1-c1ccc(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1 -US20100087427A1,6,CC(C)c1cccc([C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(Cc2ccccc2)c2ccc(Cl)cc2)c1>>CC(C)c1cccc([C@@H]2CNC[C@@H]2CN(Cc2ccccc2)c2ccc(Cl)cc2)c1 -US20140154179A1,6,CCOC(=O)c1ccn(-c2ccccc2C)n1>>Cc1ccccc1-n1ccc(C(=O)O)n1 -US20100105607A1,1,CCCCCCO.O=C(O)CBr>>CCCCCCOCC(=O)O -US06265605B1,2,CC(=O)O.O=C(O)CNCC(=O)O>>CC(=O)N(CC(=O)O)CC(=O)O -US20060094767A1,1,CC1(CCOS(C)(=O)=O)Cn2cc([N+](=O)[O-])nc2O1.O=c1[nH]nc(-c2ccncc2)o1>>CC1(CCn2nc(-c3ccncc3)oc2=O)Cn2cc([N+](=O)[O-])nc2O1 -US20080182906A1,2,NCC1(Cc2ccc(CCO)cc2)CCCC1.O=S(=O)(Cl)c1cccnc1>>O=S(=O)(NCC1(Cc2ccc(CCO)cc2)CCCC1)c1cccnc1 -US20040192708A1,2,Cc1nn(C)c(Cl)c1S(=O)(=O)Nc1ccc(CC(=O)O)nc1.Nc1[nH]c(=O)n(Cc2ccccc2F)c(=O)c1N>>Cc1nn(C)c(Cl)c1S(=O)(=O)Nc1ccc(CC(=O)Nc2c(N)[nH]c(=O)n(Cc3ccccc3F)c2=O)nc1 -US20150141409A1,1,ClCCN1CCN(Cc2ccccc2)CC1.O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1>>O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)OCCN1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 -US20100144772A1,6,CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1>>CC(C)(Oc1ccc(Cl)cc1)C(=O)O -US20110190278A1,9,CC(C)(C)OC(=O)N1CC[C@@](O)(c2ccccc2)[C@H](O)C1>>CC(C)(C)OC(=O)N1CC[C@@H](c2ccccc2)[C@H](O)C1 -US20150274653A1,2,CC1(N)COC1.O=C(O)c1c(Cl)ccc(S(=O)(=O)Cl)c1F>>CC1(NS(=O)(=O)c2ccc(Cl)c(C(=O)O)c2F)COC1 -US07314937B2,1,CC=O.c1cc2c(cc1OCCCCN1CCCCC1)CNCC2>>CCN1CCc2ccc(OCCCCN3CCCCC3)cc2C1 -US04699905,1,CC(C)(C)OC(=O)CBr.O=C1NCC(c2ccco2)SCC1N1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)CN1CC(c2ccco2)SCC(N2C(=O)c3ccccc3C2=O)C1=O -US20130005721A1,1,CCOC(=O)c1cc2cc(COS(C)(=O)=O)ccn2c1-c1ccc(F)cc1.[N-]=[N+]=[N-]>>CCOC(=O)c1cc2cc(CN=[N+]=[N-])ccn2c1-c1ccc(F)cc1 -US20070244131A1,6,CCOC(=O)CNC(=O)c1cccc(-c2cc(NCCc3ccc(Cl)cc3Cl)nc(OC)n2)c1>>COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2cccc(C(=O)NCC(=O)O)c2)n1 -US20140142074A1,6,CS(=O)(=O)NCc1ccc(C(=O)OCC(=O)OCc2ccccc2)cc1>>CS(=O)(=O)NCc1ccc(C(=O)OCC(=O)O)cc1 -US20150210722A1,1,COc1cc(Br)cc([N+](=O)[O-])c1.O=S([O-])C1CC1>>COc1cc([N+](=O)[O-])cc(S(=O)(=O)C2CC2)c1 -US07521461B2,2,CCCCCCCNCCc1ccc(Cl)cc1.COC(=O)c1ccccc1OCc1ccc(CC(=O)O)cc1>>CCCCCCCN(CCc1ccc(Cl)cc1)C(=O)Cc1ccc(COc2ccccc2C(=O)OC)cc1 -US20060205718A1,1,CCOC(=O)N1CCC(N)CC1.Clc1nc2ccccc2s1>>CCOC(=O)N1CCC(Nc2nc3ccccc3s2)CC1 -US20090118280A1,1,CC(C(=O)N1CCCC1)c1ccc(Br)cc1.FC(F)(F)c1n[nH]c2c1CCCC2>>CC(C(=O)N1CCCC1)c1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1 -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1ccc2ccc(C)c(C=O)c2c1>>COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3ccc(C)cc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US06136843,3,CN(C)C=O.Cc1ccc(S(=O)(=O)NC(=O)C(c2ccc3c(c2)OCO3)c2cn(C)c3cc(Br)ccc23)cc1>>Cc1ccc(S(=O)(=O)NC(=O)C(c2ccc3c(c2)OCO3)c2cn(C)c3cc(C=O)ccc23)cc1 -US20150152096A1,1,CCOC(=O)C1=C(CBr)NC(c2ncns2)=NC1c1ccc(F)cc1Br.O=C(O)CC1COCCN1>>CCOC(=O)C1=C(CN2CCOCC2CC(=O)O)NC(c2ncns2)=NC1c1ccc(F)cc1Br -US06586475B1,2,CN(C)CCN.COC(=O)Cc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1>>CN(C)CCNC(=O)Cc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1 -US20070142384A1,6,CCOC(=O)CC(c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1)c1nc(C)cs1>>Cc1csc(C(CC(=O)O)c2ccc(OCc3cccc(-c4ccc(C(F)(F)F)cc4)c3)cc2)n1 -US20100184601A1,3,Brc1ccc(Br)c2nsnc12.COC(=O)c1ccc(B(O)O)cc1>>COC(=O)c1ccc(-c2ccc(Br)c3nsnc23)cc1 -US20070105846A1,1,CCOC(=O)c1cccc(N)c1.COC(=O)C(=O)c1ccc(CBr)cc1>>CCOC(=O)c1cccc(NCc2ccc(C(=O)C(=O)OC)cc2)c1 -US07439243B2,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1cccc(Cc2cnc3c(Cl)cccc3c2)c1>>CC(C)(C)OC(=O)N1CCN(c2cccc3cc(Cc4cccc(Cl)c4)cnc23)CC1 -US20090305998A1,3,COc1cccc(B2OCCN(c3ccccc3)CCO2)n1.Cc1nc(N)nc2c1C(NOC1CCCCO1)=N[C@@H](c1ccc(F)cc1Br)C2>>COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOC3CCCCO3)=N2)n1 -US20150025070A1,2,BrCCNCCBr.CCOC(=O)Cl>>CCOC(=O)N(CCBr)CCBr -US20040229874A1,1,CN1CCN(c2ccccc2-c2ccc(COS(C)(=O)=O)cc2)CC1.c1ccc2[nH]ccc2c1>>CN1CCN(c2ccccc2-c2ccc(Cn3ccc4ccccc43)cc2)CC1 -US20150157641A1,2,Nc1ccc(F)c(C23CN(c4ncc(F)cn4)CC2CSC(NC(=O)c2ccccc2)=N3)c1.O=C(O)c1ccc(F)cn1>>O=C(NC1=NC2(c3cc(NC(=O)c4ccc(F)cn4)ccc3F)CN(c3ncc(F)cn3)CC2CS1)c1ccccc1 -US07514441B2,1,CCOC(=O)c1cnn(C(C)C(O)c2ccccc2)c1N>>CCOC(=O)c1cnn2c1NC(c1ccccc1)C2C -US20050245563A1,6,Cc1[nH]nc2c1c(=O)[nH]c1c(OCCCNC(=O)OC(C)(C)C)cccc12>>Cc1[nH]nc2c1c(=O)[nH]c1c(OCCCN)cccc12 -US07648997B2,1,CC(=O)Cl.NOCCCCn1cnc2c(N)nc3c(c21)CCCC3>>CC(=O)NOCCCCn1cnc2c(N)nc3c(c21)CCCC3 -US20110021500A1,2,FC(F)(F)CNCc1ccccc1.O=C(O)c1cc(Cl)ncn1>>O=C(c1cc(Cl)ncn1)N(Cc1ccccc1)CC(F)(F)F -US05663337,1,CCBr.COC(=O)Cc1cccc(O)c1>>CCOc1cccc(CC(=O)OC)c1 -US05166430,8,NS(=O)(=O)c1ccccc1SCc1ccccc1.OO>>NS(=O)(=O)c1ccccc1S(=O)Cc1ccccc1 -US08772480B2,9,Cc1nc(Cl)cc(Cl)n1.N>>Cc1nc(N)cc(Cl)n1 -US08492437B2,6,CN(C)Cc1cc(CC(=O)OC(C)(C)C)ccc1Oc1ccc(C(=O)NCCc2ccc(Cl)cc2)cc1>>CN(C)Cc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NCCc2ccc(Cl)cc2)cc1 -US08071592B2,7,COc1ccc([N+](=O)[O-])c(NCC(OC)OC)n1>>COc1ccc(N)c(NCC(OC)OC)n1 -US20060166940A1,6,CC(C)(C)OC(=O)N[C@@](C)(CO)CCc1ccc(OCCCC(F)(F)C(F)(F)F)cc1>>C[C@](N)(CO)CCc1ccc(OCCCC(F)(F)C(F)(F)F)cc1 -US04511581,2,CC1(C)CCc2c(N)cccc21.Cc1ccccc1C(=O)Cl>>Cc1ccccc1C(=O)Nc1cccc2c1CCC2(C)C -US20110263628A1,1,CC(C)(C)OC(=O)N1CCNCC1.N#CBr>>CC(C)(C)OC(=O)N1CCN(C#N)CC1 -US08003785B2,1,CC(C)Oc1cc(C(=O)NC2CCN(C)CC2)ccc1N.CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21>>CC(C)Oc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US07572823B2,2,C[Si](C)(C)c1ccc(CNCCc2ccc(Cl)c(Cl)c2)cc1.O=C(O)c1c(F)c(Cl)cc2cc[nH]c12>>C[Si](C)(C)c1ccc(CN(CCc2ccc(Cl)c(Cl)c2)C(=O)c2c(F)c(Cl)cc3cc[nH]c23)cc1 -US20120101105A1,6,C[C@@H](NC(=O)COc1ccc(C(F)(F)F)cc1)c1ccc(OCc2ccccc2)cn1>>C[C@@H](NC(=O)COc1ccc(C(F)(F)F)cc1)c1ccc(O)cn1 -US06451804B1,1,CCOC(=S)c1cnc(C)nc1Cl.Nc1ccccc1>>CCOC(=S)c1cnc(C)nc1Nc1ccccc1 -US05972984,2,CC[C@H](C)[C@@H](CNCc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccc(C#N)cc1.COC(=O)Cl>>CC[C@H](C)[C@@H](CN(Cc1cccc2ccccc12)C(=O)OC)NC(=O)Cc1cncn1Cc1ccc(C#N)cc1 -US20130065876A1,2,CN1CCN(N)CC1=O.O=C(O)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1>>CN1CCN(NC(=O)c2cnc(OCC(F)(F)F)c(-c3ccc(Cl)cc3)c2)CC1=O -US20120208819A1,1,C#CCN.Clc1ncnc2ccc(I)cc12>>C#CCNc1ncnc2ccc(I)cc12 -US08952001B2,1,CSc1nc(N)nc(C(C)O)n1.Oc1ccccc1Cl>>CSc1nc(N)nc(C(C)Oc2ccccc2Cl)n1 -US20110039874A1,3,Brc1cccc(OCc2ccccc2)c1.N#Cc1cccc(B(O)O)c1>>N#Cc1cccc(-c2cccc(OCc3ccccc3)c2)c1 -US20100267688A1,9,N.O=C(O)c1cnc(C2CCC3(CC2)OCCO3)s1>>NC(=O)c1cnc(C2CCC3(CC2)OCCO3)s1 -US05958935,1,COc1cc(Nc2nc(C)cc(Cl)n2)cc(OC)c1OC.[O-]c1ccccc1>>COc1cc(Nc2nc(C)cc(Oc3ccccc3)n2)cc(OC)c1OC -US20070225349A1,1,C=CCBr.COc1ccc(-c2n[nH]c3c(C)cccc23)cc1>>C=CCn1nc(-c2ccc(OC)cc2)c2cccc(C)c21 -US20140057896A1,3,CC(=O)N1CCn2nc(Nc3cc(Br)cn(C)c3=O)cc2C1.CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCn2c(cc3c2CCCC3)C1=O>>CC(=O)OCc1c(-c2cc(Nc3cc4n(n3)CCN(C(C)=O)C4)c(=O)n(C)c2)cccc1N1CCn2c(cc3c2CCCC3)C1=O -US05608101,2,CS(=O)(=O)Cl.O=C(O)c1ccc(O)cc1Cl>>CS(=O)(=O)Oc1ccc(C(=O)O)c(Cl)c1 -US08569484B2,1,CCOC(=O)C(=CN[C@H](CO)C(C)(C)C)C(=O)c1cc(I)c(F)nc1F>>CCOC(=O)c1cn([C@H](CO)C(C)(C)C)c2nc(F)c(I)cc2c1=O -US20150094330A1,6,COC(=O)c1ccc(CCc2cccc3c2CN(Cc2cccc(OC)c2)C3)cc1>>COc1cccc(CN2Cc3cccc(CCc4ccc(C(=O)O)cc4)c3C2)c1 -US08143263B2,6,COC[C@H](C)OC[C@H](O[Si](C)(C)C(C)(C)C)C(=O)Nc1ccc(C)cn1>>COC[C@H](C)OC[C@H](O)C(=O)Nc1ccc(C)cn1 -US08044069B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NCCNC1c1ccccc1>>CC(C)(C)OC(=O)N1CCNC(=O)C1c1ccccc1 -US20150191419A1,6,CC(C)(C)OC(=O)NCC(=O)CCC(=O)OCCCC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCC(=O)CCC(=O)OCCCC(=O)O -US20130178633A1,1,FC(F)(F)c1cc(Cl)ccn1.NCc1ccccc1O>>Oc1ccccc1CNc1ccnc(C(F)(F)F)c1 -US20090137557A1,3,Brc1ccc(-c2cnco2)s1.Cc1nc(-c2ccccc2OCc2ccccc2)n(CCc2ccccc2)c(=O)c1Br>>Cc1nc(-c2ccccc2OCc2ccccc2)n(CCc2ccccc2)c(=O)c1-c1ccc(-c2cnco2)s1 -US05849801,6,CCOC(=O)C1CCN(C2C=C(C)C(=O)CC(C)(C)C2O)CC1>>CC1=CC(N2CCC(C(=O)O)CC2)C(O)C(C)(C)CC1=O -US06384030B1,1,CC(=O)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O.C[C@H](N)c1cccc2ccccc12>>CC(NC(C)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O)c1cccc2ccccc12 -US20110152246A1,7,O=C(O)c1ccc([N+](=O)[O-])c(O)c1O>>Nc1ccc(C(=O)O)c(O)c1O -US09133181B2,3,COCOc1ccc(B(O)O)cc1.Cc1nn(C2CCCCO2)c2nc(Br)cc(CO)c12>>COCOc1ccc(-c2cc(CO)c3c(C)nn(C4CCCCO4)c3n2)cc1 -US20100286114A1,6,CCOC(=O)c1cccc(N2CCN(C(=O)OC(C)(C)C)CC2)c1>>CC(C)(C)OC(=O)N1CCN(c2cccc(C(=O)O)c2)CC1 -US20020193367A1,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1.CC(C)(C)OC(=O)Nc1cc(N2CCCC2)c(C#N)cc1N>>CC(C)(C)OC(=O)Nc1cc(N2CCCC2)c(C#N)cc1NC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1 -US07560463B2,1,CCC(CC)CBr.NC(=O)c1ccc(Oc2ccc3c(c2)CCCNC3)nc1>>CCC(CC)CN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1 -US08309718B2,3,CC(C)(C)[Si](C)(C)OC1CCC(=O)CC1.CCOP(=O)(CC#N)OCC>>CC(C)(C)[Si](C)(C)OC1CCC(=CC#N)CC1 -US20090042724A1,3,Nc1ccccc1Br.OB(O)c1ccc(Cl)cc1Cl>>Nc1ccccc1-c1ccc(Cl)cc1Cl -US08357717B2,2,COC(=O)c1ccc2c(c1)NCC2.COc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>COC(=O)c1ccc2c(c1)N(S(=O)(=O)c1c(C)cc(OC)cc1C)CC2 -US20120059014A1,2,CC(C)OC(=O)N1CCC(C(C)CO)CC1.CS(=O)(=O)Cl>>CC(C)OC(=O)N1CCC(C(C)COS(C)(=O)=O)CC1 -US07709647B2,2,N#Cc1ccc2c(c1)CC(N)CN2.O=C(O)[C@@H](O)c1ccccc1>>N#Cc1ccc2c(c1)C[C@H](NC(=O)[C@@H](O)c1ccccc1)CN2 -US07153517B2,1,C=CCCBr.Oc1ccc(O)cc1>>C=CCCOc1ccc(O)cc1 -US05654299,9,CSc1ccccc1C1(O)CCN(C(=O)OCc2ccccc2)CC1>>CSc1ccccc1C1CCN(C(=O)OCc2ccccc2)CC1 -US06083651,1,Cc1ccc(I)cc1.c1ccc2c(c1)Nc1ccccc1S2>>Cc1ccc(N2c3ccccc3Sc3ccccc32)cc1 -US20140377791A1,3,CN(C)c1ccc2cc(C=O)c([Si](C)(C)C(C)(C)C)cc2c1.N#CCC#N>>CN(C)c1ccc2cc(C=C(C#N)C#N)c([Si](C)(C)C(C)(C)C)cc2c1 -US20070105819A1,2,Nc1cc(C(=O)O)ccc1Cc1ccccc1C(=O)O>>O=C(O)c1ccc2c(c1)NC(=O)c1ccccc1C2 -US20050137243A1,2,Nc1ccc2cnn(CCN3CCCC3)c2c1.O=C(O)Cc1ccc(OCc2ccccc2)cc1>>O=C(Cc1ccc(OCc2ccccc2)cc1)Nc1ccc2cnn(CCN3CCCC3)c2c1 -US07544835B2,2,COC(=O)C(Cc1cccc(CCO)c1)C(=O)OC.O=C=Nc1ccc(Cl)cc1Cl>>COC(=O)C(Cc1cccc(CCOC(=O)Nc2ccc(Cl)cc2Cl)c1)C(=O)OC -US08461162B2,1,CC(C)(O)CN.Fc1ccc(-c2cnc3c(Br)cnn3c2)cn1>>CC(C)(O)CNc1ccc(-c2cnc3c(Br)cnn3c2)cn1 -US20090118332A1,2,CSc1ccc(C(=O)O)cc1[N+](=O)[O-].N#Cc1ccc(C2CCNCC2)cc1>>CSc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1[N+](=O)[O-] -US20100120793A1,1,CCOC(=O)C1(CI)CCN(C(=O)c2ccc(F)cc2)C1.Oc1cnc(-c2ccc(Cl)cc2)cn1>>CCOC(=O)C1(COc2cnc(-c3ccc(Cl)cc3)cn2)CCN(C(=O)c2ccc(F)cc2)C1 -US20100130748A1,9,NC(=O)c1cc([N+](=O)[O-])c(N)c(F)c1F>>N#Cc1cc([N+](=O)[O-])c(N)c(F)c1F -US20120095064A1,1,Fc1c(Cl)cccc1CBr.O=C1c2ccccc2C(=O)N1c1cc[nH]n1>>O=C1c2ccccc2C(=O)N1c1ccn(Cc2cccc(Cl)c2F)n1 -US05270327,2,C1CCN(CC2CCCCN2)CC1.O=C1CC(C(=O)Cl)c2cc(Cl)c(Cl)cc21>>O=C1CC(C(=O)N2CCCCC2CN2CCCCC2)c2cc(Cl)c(Cl)cc21 -US20100249123A1,3,CC(C)(C#N)c1ccc(N)cc1Br.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2cc(N)ccc2C(C)(C)C#N)cn1 -US20090042726A1,9,Cc1nn(C)c(C(=O)O)c1C(F)(F)F.N>>Cc1nn(C)c(C(N)=O)c1C(F)(F)F -US04035411,1,CCO[Si](OCC)(OCC)C(C)Br.CN(C)Cc1ccccc1>>CCO[Si](OCC)(OCC)C(C)[N+](C)(C)Cc1ccccc1 -US20100286152A1,6,COC(=O)C(=O)C(C)(c1ccc2c(c1)OCO2)N1CCN(C)CC1>>CN1CCN(C(C)(C(=O)C(=O)O)c2ccc3c(c2)OCO3)CC1 -US20140155385A1,2,Nc1nccn2c([C@@H]3CCCN3)nc(-c3ccc(C(=O)Nc4ccccn4)cc3)c12.O=C(O)/C=C/CN1CCCC1>>Nc1nccn2c([C@@H]3CCCN3C(=O)/C=C/CN3CCCC3)nc(-c3ccc(C(=O)Nc4ccccn4)cc3)c12 -US20070287725A1,2,CCOCC(=O)Cl.Nc1cnc2cccnc2c1NCc1cc(-c2ccc(F)cc2)no1>>CCOCC(=O)Nc1cnc2cccnc2c1NCc1cc(-c2ccc(F)cc2)no1 -US20150110809A1,4,CC(=O)C(C)Br.Cc1cc(C)c(NC(N)=S)c(C)c1>>Cc1cc(C)c(Nc2nc(C)c(C)s2)c(C)c1 -US20150225399A1,2,CC(N)CO.CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCOCC2)c1=O>>CC(CO)NC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCOCC2)c1=O -US20030119813A1,1,CC(C)(C)c1ccccc1O.COc1cc2c(cc1OC)-c1cc(Cl)nc(=O)n1CC2>>COc1cc2c(cc1OC)-c1cc(Oc3ccccc3C(C)(C)C)nc(=O)n1CC2 -US08952010B2,7,CCOC(=O)C(F)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC(C)(C)[Si](OCC(F)CO)(c1ccccc1)c1ccccc1 -US05302590,2,C=CCN.Cc1nnc2n1-c1sc(CCc3ccc(CC(=O)Nc4cccc(/C=C/c5nc(C6CCC6)cs5)c4)c(C(=O)O)c3)cc1C(c1ccccc1Cl)=NC2>>C=CCNC(=O)c1cc(CCc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)ccc1CC(=O)Nc1cccc(/C=C/c2nc(C3CCC3)cs2)c1 -US20080139572A1,1,COc1cnc(Br)c2[nH]ccc12.Clc1cn[nH]c1>>COc1cnc(-n2cc(Cl)cn2)c2[nH]ccc12 -US20050026925A1,1,CCBr.CCOC(=O)c1cc2cc(O)c(Cl)nc2n1C(=O)OC(C)(C)C>>CCOC(=O)c1cc2cc(OCC)c(Cl)nc2n1C(=O)OC(C)(C)C -US08987486B2,2,CCCCCCC/C=C/C(=O)O.CCCCCCCNCC>>CCCCCCC/C=C/C(=O)N(CC)CCCCCCC -US08147818B2,7,O=C(O)CC/C=C/c1cccc(Br)c1>>O=C(O)CCCCc1cccc(Br)c1 -US20130190307A1,2,NNc1cnc2ccc(Br)cc2n1.O=C(O)C1CC1>>O=C(NNc1cnc2ccc(Br)cc2n1)C1CC1 -US20080015222A1,7,COc1cc(NC(=O)Cn2cnc3cccc(C(=O)O)c32)cc(OC)c1>>COc1cc(NC(=O)Cn2cnc3cccc(CO)c32)cc(OC)c1 -US07235661B2,1,Clc1ccc2scc(CBr)c2c1.c1ccc(N2CCNCC2)nc1>>Clc1ccc2scc(CN3CCN(c4ccccn4)CC3)c2c1 -US20140288069A1,1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NCC(O)CN1CCCCC1>>OC(CNc1ccc2ncc(-c3cc4ccccc4o3)n2n1)CN1CCCCC1 -US20110009402A1,1,COCC(O)(CC=O)c1ccccc1.C[C@H](N)c1ccc(Br)cc1>>COCC(O)(CCN[C@@H](C)c1ccc(Br)cc1)c1ccccc1 -US04010177,1,C=CCN.ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>C=CCNCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2 -US06946477B2,2,CC(C)(C)OC(=O)N1CCCC(CNc2ccccc2)C1.CCN=C=O>>CCNC(=O)N(CC1CCCN(C(=O)OC(C)(C)C)C1)c1ccccc1 -US20030166689A1,2,Nc1nc(-c2ccccc2)cs1.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>O=S(=O)(Nc1nc(-c2ccccc2)cs1)c1ccc(-c2ccccc2)cc1 -US07259163B2,8,N#Cc1ccnc(CO)c1>>N#Cc1ccnc(C=O)c1 -US20090143385A1,2,CC(C)(N)CO.Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)nn1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(C)(C)CO)nn1 -US20140018371A1,3,CC(C)(C)OC(=O)N1CCC(COC2CC=C(B3OC(C)(C)C(C)(C)O3)CC2)CC1.Cc1nc(S(C)(=O)=O)ccc1OS(=O)(=O)C(F)(F)F>>Cc1nc(S(C)(=O)=O)ccc1C1=CCC(OCC2CCN(C(=O)OC(C)(C)C)CC2)CC1 -US20030229089A1,1,CCOC(=O)c1sc(N2CCCC2CO)nc1N.COc1ccc(C=O)cc1Cl>>CCOC(=O)c1sc(N2CCCC2CO)nc1NCc1ccc(OC)c(Cl)c1 -US08278442B2,1,N#Cc1ccc(Cl)nc1.O=Cc1ccc(O)c2ncccc12>>N#Cc1ccc(Oc2ccc(C=O)c3cccnc23)nc1 -US08354398B2,6,COC(=O)c1noc(-c2ccccc2)c1CCC(F)(F)F>>O=C(O)c1noc(-c2ccccc2)c1CCC(F)(F)F -US04160096,1,CCS(=O)O.Cc1ncc([N+](=O)[O-])n1CCBr>>CCS(=O)(=O)CCn1c([N+](=O)[O-])cnc1C -US20060035938A1,2,CS(=O)(=O)Cl.Cc1ccc(C(=O)NCc2ccc(O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1ccc(C(=O)NCc2ccc(OS(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1 -US20150175617A1,6,COC(=O)c1cccc2[nH]c([C@@]3(C)CCCN3C(=O)OCc3ccccc3)cc12>>COC(=O)c1cccc2[nH]c([C@@]3(C)CCCN3)cc12 -US20090264405A1,6,CC1CN(c2ccc(C(F)(F)F)cn2)C(C)CN1C(=O)OC(C)(C)C>>CC1CN(c2ccc(C(F)(F)F)cn2)C(C)CN1 -US20090124596A1,3,O=C(N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(I)c3)c2=O)CC1)c1cn2cc(F)ccc2n1.OB(O)c1ccc(O)cc1CN1CCOCC1>>O=C(N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(O)cc4CN4CCOCC4)c3)c2=O)CC1)c1cn2cc(F)ccc2n1 -US20150232452A1,2,CCn1cc(-c2cccc(N)c2)c(-c2ccncc2)n1.O=C=Nc1ccccc1Cl>>CCn1cc(-c2cccc(NC(=O)Nc3ccccc3Cl)c2)c(-c2ccncc2)n1 -US20030166650A1,1,C[C@H](NC(=O)OC(C)(C)C)c1cccc(Br)c1.C[C@H]1CNC[C@@H](C)O1>>C[C@H]1CN(c2cccc([C@H](C)NC(=O)OC(C)(C)C)c2)C[C@@H](C)O1 -US20100197681A1,6,COc1cc(-c2ccc3nc(NC(=O)c4ccc(CN5CCCCC5)cc4)nn3c2)ccc1OCc1ccccc1>>COc1cc(-c2ccc3nc(NC(=O)c4ccc(CN5CCCCC5)cc4)nn3c2)ccc1O -US04294606,2,Nc1cc(N)c(Cl)cc1Cl.O=C(Cl)CCCCl>>Nc1cc(NC(=O)CCCCl)c(Cl)cc1Cl -US20120101083A1,2,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCCC(=O)O)CC4)no2)cc1C#N.CNC>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCCC(=O)N(C)C)CC4)no2)cc1C#N -US20090299042A1,1,BrCCCOc1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(O)(c1cccs1)c1cccs1>>O=C(O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)C(O)(c1cccs1)c1cccs1 -US20120184561A1,2,COc1ccccc1-n1nc(C(C)(C)C)cc1N.O=C(O)Cc1ccc(-n2cnc3cccnc32)cc1>>COc1ccccc1-n1nc(C(C)(C)C)cc1NC(=O)Cc1ccc(-n2cnc3cccnc32)cc1 -US04920136,1,C1COCCN1.CC(=O)c1cc(C#N)c(Cl)nc1C>>CC(=O)c1cc(C#N)c(N2CCOCC2)nc1C -US05736540,2,CCCCS(=O)(=O)Cl.COc1cc(C(=O)N2Cc3cccn3Cc3ccccc32)ccc1N>>CCCCS(=O)(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1OC -US20070027178A1,6,Cc1c(F)cc(Cl)c2c1c1c(n2C)CCN(C(=O)OC(C)(C)C)C1>>Cc1c(F)cc(Cl)c2c1c1c(n2C)CCNC1 -US04239759,6,CC(CCN1C(=O)c2ccccc2C1=O)c1ccc(-c2ccc(F)cc2)cc1>>CC(CCN)c1ccc(-c2ccc(F)cc2)cc1 -US20080090774A1,1,N[C@H]1C[C@@H](CO)[C@H](O)[C@@H]1O.Nc1ncnc(Cl)c1[N+](=O)[O-]>>Nc1ncnc(N[C@H]2C[C@@H](CO)[C@H](O)[C@@H]2O)c1[N+](=O)[O-] -US04353827,6,CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1c(Cl)cccc1-2>>O=C(O)c1ncn2c1[C@@H]1CCCN1C(=O)c1c(Cl)cccc1-2 -US20080255105A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc(N)ccc1Br>>Cc1cc(NC(=O)OC(C)(C)C)ccc1Br -US20140303121A1,2,Cc1noc(C)c1-c1cnc2c(c1)c(CC1CCNCC1)cn2C.O=S(=O)(Cl)c1ccccc1>>Cc1noc(C)c1-c1cnc2c(c1)c(CC1CCN(S(=O)(=O)c3ccccc3)CC1)cn2C -US20100120785A1,1,CS(=O)(=O)c1ccc(-c2nccnc2N2CCNCC2)cc1.Cc1nn(C)c(C)c1C=O>>Cc1nn(C)c(C)c1CN1CCN(c2nccnc2-c2ccc(S(C)(=O)=O)cc2)CC1 -US20120029190A1,1,N#Cc1cccc(CBr)c1.c1ccc(-c2nc3c(o2)CNCC3)nc1>>N#Cc1cccc(CN2CCc3nc(-c4ccccn4)oc3C2)c1 -US07332510B2,1,Cc1nc(C#Cc2ccnc(C#N)c2)c[nH]1.OB(O)c1ccc(F)cc1>>Cc1nc(C#Cc2ccnc(C#N)c2)cn1-c1ccc(F)cc1 -US20080255124A1,1,N#Cc1ccc(N(CCO)CC(F)(F)F)cc1C(F)(F)F.Oc1cccc(F)c1>>N#Cc1ccc(N(CCOc2cccc(F)c2)CC(F)(F)F)cc1C(F)(F)F -US20050261177A1,2,CC1CCC(O)CC1.CS(=O)(=O)Cl>>C[C@H]1CC[C@@H](OS(C)(=O)=O)CC1 -US20110118257A1,7,Nc1ncnc2c1c(C#CCO)nn2Cc1oc2ccccc2c(=O)c1-c1ccccc1>>Nc1ncnc2c1c(CCCO)nn2Cc1oc2ccccc2c(=O)c1-c1ccccc1 -US20090181966A1,6,COC(=O)C(C)(C)CCOc1ccc(C(=O)N2c3ccccc3[C@H](N(C(=O)C(C)C)c3ccc(Cl)cc3)C[C@@H]2C)cc1>>CC(C)C(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCC(C)(C)C(=O)O)cc2)c2ccccc21 -US20090203667A1,1,C1CCNC1.O=Cc1ccc(/C(=C\C=C\C(=O)Nc2cccc3cnccc23)c2ccc(C(F)(F)F)cc2)cc1>>O=C(/C=C/C=C(\c1ccc(CN2CCCC2)cc1)c1ccc(C(F)(F)F)cc1)Nc1cccc2cnccc12 -US05491167,1,C[C@H]1C=CC2=C[C@@H](C(C)(C)C)C[C@H](O)[C@@H]2[C@@]1(CC[C@@H]1C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O1)O[SiH](C)C.Cc1cccc(C)c1OC(C)C(=O)O>>Cc1cccc(C)c1OC(C)C(=O)O[C@H]1C[C@H](C(C)(C)C)C=C2C=C[C@H](C)[C@](CC[C@@H]3C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O3)(O[SiH](C)C)[C@H]21 -US20140155511A1,1,O=Cc1ccccc1F.Sc1ccccc1>>O=Cc1ccccc1Sc1ccccc1 -US20090227591A1,3,COc1ccc(Cl)cc1I.OB(O)C1=C(Br)CCC1>>COc1ccc(Cl)cc1C1=C(Br)CCC1 -US20120129811A1,2,CC(C)Oc1ccncc1N=C=S.Cn1cnc2c(N)cccc21>>CC(C)Oc1ccncc1NC(=S)Nc1cccc2c1ncn2C -US20020115853A1,1,CCCCNCC(=O)O.O=[N+]([O-])c1ccc(Br)cc1F>>CCCCN(CC(=O)O)c1cc(Br)ccc1[N+](=O)[O-] -US20050096312A1,2,COc1cc(N2CCCN(C)CC2)c2oc(C(=O)O)cc(=O)c2c1.Nc1ccc(N2CCOCC2)cc1>>COc1cc(N2CCCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1 -US06498172B1,2,COC(=O)CCc1cccc(CNCc2ccc3c(c2)OCO3)c1.O=S(=O)(Cl)c1ccccc1>>COC(=O)CCc1cccc(CN(Cc2ccc3c(c2)OCO3)S(=O)(=O)c2ccccc2)c1 -US05185333,2,CN1CCSc2c(C(=O)O)cc(Cl)cc21.NC1CN2CCC1CC2>>CN1CCSc2c(C(=O)NC3CN4CCC3CC4)cc(Cl)cc21 -US20080058293A1,2,CCOC(=O)C1CCN(c2ccc3c(N)c(Cl)ccc3n2)CC1.O=C(O)CCc1ccccc1Cl>>CCOC(=O)C1CCN(c2ccc3c(NC(=O)CCc4ccccc4Cl)c(Cl)ccc3n2)CC1 -US20080249107A1,2,COC(=O)c1ccc(C)c(N)c1.COc1ccc(/C=C/C(=O)O)c(OC)c1OC>>COC(=O)c1ccc(C)c(NC(=O)C=Cc2ccc(OC)c(OC)c2OC)c1 -US04719219,6,CCCN1CCCC(c2cccc(OC)c2)C1>>CCCN1CCCC(c2cccc(O)c2)C1 -US20040209866A1,1,Cc1cc(Cl)c(C(=O)C=C(Nc2ccccc2)Nc2ccccc2)c(Cl)n1>>Cc1cc(Cl)c2c(=O)cc(Nc3ccccc3)n(-c3ccccc3)c2n1 -US08507690B2,6,CC(=O)Nc1nc(CCc2ccc(COC(=O)NNC(=O)OC(C)(C)C)c(F)c2)cs1>>CC(=O)Nc1nc(CCc2ccc(COC(=O)NN)c(F)c2)cs1 -US20130019348A1,3,C=C(C)B1OC(C)(C)C(C)(C)O1.O=[N+]([O-])c1cc(F)ccc1Cl>>C=C(C)c1ccc(F)cc1[N+](=O)[O-] -US05773451,1,Cc1c(Cl)cc[n+]([O-])c1C.OCCCS>>Cc1c(SCCCO)cc[n+]([O-])c1C -US06903097B2,3,C#CCO.CCOC(=O)c1cn(C)c2ccc(Cl)nc2c1=O>>CCOC(=O)c1cn(C)c2ccc(C#CCO)nc2c1=O -US08598173B2,2,CC(=O)c1ccc(N2CCNCC2)cc1.CCOC(=O)Nc1nc2ccc(Cl)cc2nc1OC>>COc1nc2cc(Cl)ccc2nc1NC(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 -US20110166139A1,2,CO.Cn1cc([N+](=O)[O-])c(C(=O)O)n1>>COC(=O)c1nn(C)cc1[N+](=O)[O-] -US07102001B2,6,CCOC(=O)c1cn2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c2c1C>>Cc1c(C(=O)O)cn2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12 -US20030144263A1,2,CS(=O)(=O)Cl.Cc1cncn1-c1ccc(N2C[C@H](CO)OC2=O)cc1F>>Cc1cncn1-c1ccc(N2C[C@H](COS(C)(=O)=O)OC2=O)cc1F -US20050267095A1,4,BrCCOCCBr.CCN(C)CCCOc1ccc(C2(CN)CCOCC2)cc1>>CCN(C)CCCOc1ccc(C2(CN3CCOCC3)CCOCC2)cc1 -US20150225449A1,1,COC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H](C)N.O=[N+]([O-])c1ccccc1F>>COC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H](C)Nc1ccccc1[N+](=O)[O-] -US20140088124A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.COC(=O)c1cc(O)ccn1>>COC(=O)c1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)ccn1 -US20130035310A1,2,Cc1cc(S(=O)(=O)Cl)ccc1NC(=O)C(F)(F)F.Nc1nccs1>>Cc1cc(S(=O)(=O)Nc2nccs2)ccc1NC(=O)C(F)(F)F -US07495007B2,9,Cc1ccc(I)cc1C(=O)O>>Cc1ccc(I)cc1C=O -US20140243286A1,2,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCN)c1nnc(C)n1-2.O=C(O)c1cccc(B(O)O)c1>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCNC(=O)c1cccc(B(O)O)c1)c1nnc(C)n1-2 -US07964613B2,2,CC(C)(C)OC(=O)N1CC[C@H](N)C1.O=C(Br)CBr>>CC(C)(C)OC(=O)N1CC[C@H](NC(=O)CBr)C1 -US04372953,1,Cn1nnnc1Cl.O=C(CCCS)c1ccccn1>>Cn1nnnc1SCCCC(=O)c1ccccn1 -US20150203493A1,1,CC(C)(C)[C@@H]1CC[C@@H](Oc2cccc3cc(C=O)ccc23)CC1.CCOC(=O)C1CC(N)C1(C)C>>CCOC(=O)C1CC(NCc2ccc3c(O[C@@H]4CC[C@@H](C(C)(C)C)CC4)cccc3c2)C1(C)C -US20140171404A1,2,NCCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1.O=C(O)Cc1c[nH]nn1>>O=C(Cc1c[nH]nn1)NCCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1 -US20150218096A1,6,COC(=O)c1ccc(-c2nn(C(=O)c3c(C)cc(N(C)C)cc3Cl)c3cccnc23)c(F)c1>>Cc1cc(N(C)C)cc(Cl)c1C(=O)n1nc(-c2ccc(C(=O)O)cc2F)c2ncccc21 -US05506227,7,CCOC(=O)c1ccccc1CCC(=O)c1cccc(COC2CCCCO2)c1>>CCOC(=O)c1ccccc1CC[C@H](O)c1cccc(COC2CCCCO2)c1 -US20030191133A1,2,O=C(Cl)CCCl.c1ccc2c(c1)CCNC2>>O=C(CCCl)N1CCc2ccccc2C1 -US20070093521A1,1,CCOc1cc(C=O)cc(OCC)c1F.Cc1nccc2nc(NC3CCNCC3)oc12>>CCOc1cc(CN2CCC(Nc3nc4ccnc(C)c4o3)CC2)cc(OCC)c1F -US20030153566A1,7,COC(=O)Nc1nc2c(OC)ccc([N+](=O)[O-])c2s1>>COC(=O)Nc1nc2c(OC)ccc(N)c2s1 -US20070173646A1,1,BrCCCCOc1ccccc1.N#CC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>N#CC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCCOc3ccccc3)(CC1)CC2 -US20100074083A1,1,CC1(C)CC(=O)CC(C)(C)N1.CCCCCCCCN>>CCCCCCCCNC1CC(C)(C)NC(C)(C)C1 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(C)(=O)=O)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C[C@H](S(C)(=O)=O)C[C@H]1C(=O)O -US20070093521A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.N#Cc1ccc2oc(Cl)nc2c1>>CC(C)(C)OC(=O)N1CCC(Nc2nc3cc(C#N)ccc3o2)CC1 -US09000044B2,6,COC(=O)Cc1cc2ccc(Cl)cc2c(-c2ccc(NS(=O)(=O)c3ccccc3C(F)(F)F)cc2)c1C>>Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 -US06482829B2,1,CI.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)NCN2c1ccccc1Cl>>CN1CN(c2ccccc2Cl)C2(CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)C1=O -US20060035932A1,2,CSCCC(NS(=O)(=O)c1cnc(N2CCC(CCCCCC3CCNCC3)CC2)c(Br)c1)C(=O)O.O=S(=O)(Cl)c1cc(Br)c(Cl)s1>>CSCCC(NS(=O)(=O)c1cnc(N2CCC(CCCCCC3CCN(S(=O)(=O)c4cc(Br)c(Cl)s4)CC3)CC2)c(Br)c1)C(=O)O -US08546405B2,2,C1CNCCN1.CC(C)c1ccc2c(Nc3cc(C(=O)O)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1>>CC(C)c1ccc2c(Nc3cc(C(=O)N4CCNCC4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1 -US20110046127A1,2,COc1ccc(N)cc1.O=C(O)c1cnc2ccc(CCc3ccccc3)nn12>>COc1ccc(NC(=O)c2cnc3ccc(CCc4ccccc4)nn23)cc1 -US20030114422A1,2,CC(=O)OC(C)=O.CCCCn1c(=O)c(=O)[nH]c2ccc3c(c21)CCCN3>>CCCCn1c(=O)c(=O)[nH]c2ccc3c(c21)CCCN3C(C)=O -US20130196964A1,2,O=S(=O)(Cl)c1cccc(CBr)c1.OC1CCNCC1>>O=S(=O)(c1cccc(CBr)c1)N1CCC(O)CC1 -US20050277640A1,2,CS(=O)(=O)Cl.NCc1cc(Oc2ccc(Nc3cc(-c4ccccc4)nc(N)n3)cc2)ccn1>>CS(=O)(=O)NCc1cc(Oc2ccc(Nc3cc(-c4ccccc4)nc(N)n3)cc2)ccn1 -US20100216810A1,2,N#CC1(c2cccc(C(=O)O)c2Cl)CC1.N#Cc1c(Oc2cc(N)c(F)cc2Cl)ccc2nc(NC(=O)C3CC3)sc12>>N#Cc1c(Oc2cc(NC(=O)c3cccc(C4(C#N)CC4)c3Cl)c(F)cc2Cl)ccc2nc(NC(=O)C3CC3)sc12 -US20140000716A1,3,CCCCCCCCC(CCCCCC)Cc1ccsc1Br.CN(C)C=O>>CCCCCCCCC(CCCCCC)Cc1ccsc1C=O -US04929613,1,O=C1NC(=O)c2ccccc21.OC1CCC(c2cc(F)c(Br)cc2F)C1>>O=C1c2ccccc2C(=O)N1C1CCC(c2cc(F)c(Br)cc2F)C1 -US20080234274A1,2,C1COCCN1.COc1ccccc1C(C#N)NC(=O)[C@@H]1CCCC[C@H]1C(=O)O>>COc1ccccc1C(C#N)NC(=O)[C@@H]1CCCC[C@H]1C(=O)N1CCOCC1 -US20140155415A1,2,COc1ccc(S(=O)(=O)Cl)cc1OC.C[C@@](O)(c1ccnc(-c2cccc3cc([C@H](N)c4ccccc4Cl)sc23)c1)C(F)(F)F>>COc1ccc(S(=O)(=O)N[C@@H](c2cc3cccc(-c4cc([C@@](C)(O)C(F)(F)F)ccn4)c3s2)c2ccccc2Cl)cc1OC -US06946454B2,3,Brc1ccc2c(c1)C1(CCCCC1)C(=NOCc1ccccc1)N2.COc1cccc(B(O)O)c1>>COc1cccc(-c2ccc3c(c2)C2(CCCCC2)C(=NOCc2ccccc2)N3)c1 -US20080207695A1,6,Cc1cc(NC(=O)OC(C)(C)C)nc(CO)c1CNC(=O)OCC1c2ccccc2-c2ccccc21>>Cc1cc(NC(=O)OC(C)(C)C)nc(CO)c1CN -US07259183B2,1,CC(C)(C)c1ccc(C=O)cc1.NCCc1ccc(Cl)cc1>>CC(C)(C)c1ccc(CNCCc2ccc(Cl)cc2)cc1 -US05925662,2,CCOC(=O)Cl.N#CCCC1CCc2cc(N)ccc2O1>>CCOC(=O)Nc1ccc2c(c1)CCC(CCC#N)O2 -US20100216779A1,1,COc1cc([C@@H]2CC[C@H](N3CCN(CCS(C)(=O)=O)CC3)CC2)ccc1N.O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)c1>>COc1cc([C@@H]2CC[C@H](N3CCN(CCS(C)(=O)=O)CC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US06562989B2,3,Cc1ccccc1B(O)O.N#Cc1ccc(Cl)cc1>>Cc1ccccc1-c1ccc(C#N)cc1 -US20020177594A1,2,CNC(=O)C(=O)CCCCCCC(=O)O.NNC(=O)c1cccs1>>CNC(=O)C(=O)CCCCCCC(=O)NNC(=O)c1cccs1 -US07199120B2,3,C#Cc1ccnc(SC)n1.Fc1cc(I)ccn1>>CSc1nccc(C#Cc2ccnc(F)c2)n1 -US05196548,2,O=C(Cl)OCc1ccccc1.O=C(O)[C@@H]1CC(O)CN1>>O=C(O)[C@@H]1CC(O)CN1C(=O)OCc1ccccc1 -US08492425B2,1,COc1cccc2cc(-n3nc(O)cc3C)ccc12.ClCCN1CCOCC1>>COc1cccc2cc(-n3nc(OCCN4CCOCC4)cc3C)ccc12 -US20070167451A1,1,Cc1cc(COc2ccc(C(=O)NCC3(N4CCNCC4)C(=O)NC(=O)NC3=O)cc2)c2ccccc2n1.O=Cc1cccnc1>>Cc1cc(COc2ccc(C(=O)NCC3(N4CCN(Cc5cccnc5)CC4)C(=O)NC(=O)NC3=O)cc2)c2ccccc2n1 -US05508293,9,NC(=O)c1cncc(O)c1>>N#Cc1cncc(O)c1 -US20100267774A1,7,O=[N+]([O-])c1c(F)cc(CCO)cc1F>>Nc1c(F)cc(CCO)cc1F -US05597918,1,CC(=O)[O-].Cc1ccc(N2N=C3c4cc(C(=O)CCl)sc4CCC3CC2=O)cc1>>CC(=O)OCC(=O)c1cc2c(s1)CCC1CC(=O)N(c3ccc(C)cc3)N=C21 -US20090047246A1,6,CCOC(=O)Cc1cn(Cc2nc3ccccc3s2)c2cc(-c3cc(N)cc(N)c3)ccc12>>Nc1cc(N)cc(-c2ccc3c(CC(=O)O)cn(Cc4nc5ccccc5s4)c3c2)c1 -US05028606,6,CC(=O)Nc1ccc(C(C(C)C)n2cncn2)cc1[N+](=O)[O-]>>CC(C)C(c1ccc(N)c([N+](=O)[O-])c1)n1cncn1 -US09120749B2,3,CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C.O=C(c1cnc2ccc(Br)cc2c1Nc1cccc(CCN2CCCC2)c1)C1CC1>>O=C(c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1cccc(CCN2CCCC2)c1)C1CC1 -US07772264B2,1,Cc1oc(-c2ccccc2)nc1CC[NH3+].N#C[C@@H]1CCCN1C(=O)CCl>>Cc1oc(-c2ccccc2)nc1CCNCC(=O)N1CCC[C@H]1C#N -US06906224B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1ccccc1)C(=O)CCl>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)CCl -US20040152597A1,6,COC(=O)C(C)Oc1ncccc1OC(C)=O>>COC(=O)C(C)Oc1ncccc1O -US20140303161A1,3,N#CCC(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2F)c2c(N)ncnc21.O=CC1CC1>>N#CC(=CC1CC1)C(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2F)c2c(N)ncnc21 -US20080269284A1,9,CCC(COS(C)(=O)=O)NC(=O)OC(C)(C)C.[C-]#N>>CCC(CC#N)NC(=O)OC(C)(C)C -US20150080350A1,1,COc1ccc(CCl)cc1.NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl>>COc1ccc(COC(=O)c2cc(S(N)(=O)=O)c(Cl)cc2NCc2ccco2)cc1 -US20050245529A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.CC1CCN([C@@H]2CCCN(c3ccc(I)cc3)C2)CC1>>CC1CCN([C@@H]2CCCN(c3ccc(C#Cc4ccc(-c5ccc(Cl)cc5)cn4)cc3)C2)CC1 -US04593104,1,CCc1cccc(C)c1N(CCl)C(=O)CCl.Cc1n[nH]c(C)c1Cl>>CCc1cccc(C)c1N(Cn1nc(C)c(Cl)c1C)C(=O)CCl -US20040058965A1,5,COCCl.OCc1coc(-c2ccccc2)n1>>COCOCc1coc(-c2ccccc2)n1 -US20050131016A1,7,O=C(O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)ccc3[nH]2)Cc2ccccc21>>O=C(NC1Cc2ccccc2N(CCO)C1=O)c1cc2cc(Cl)ccc2[nH]1 -US08188139B2,7,FC(F)(F)c1cccc2[nH]ccc12>>FC(F)(F)c1cccc2c1CCN2 -US05686449,1,NC1CCCCC1.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1NC1CCCCC1 -US04124760,3,O=C1CNC(=O)N1.O=CC=Cc1ccccc1>>O=C1NC(=O)C(=CC=Cc2ccccc2)N1 -US04762838,1,O=C(O)c1cc(Cl)c(Cl)cc1[N+](=O)[O-].Oc1ccc(Cl)cc1>>O=C(O)c1cc(Oc2ccc(Cl)cc2)c(Cl)cc1[N+](=O)[O-] -US20100010035A1,3,CCOCN(c1cc(C)on1)S(=O)(=O)c1cc(C)sc1Br.O=Cc1ccc(B(O)O)cc1>>CCOCN(c1cc(C)on1)S(=O)(=O)c1cc(C)sc1-c1ccc(C=O)cc1 -US20090275593A1,2,CN(C)C1CCNC1.Nc1c(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)cnc2c(C(=O)O)cnn12>>CN(C)C1CCN(C(=O)c2cnn3c(N)c(-c4ccc(NS(=O)(=O)c5cccc(Cl)c5Cl)cc4)cnc23)C1 -US20120316147A1,2,CC(C)(C)N.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>CC(C)(C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 -US20150232463A1,3,CN1CC(=O)OB(c2ccc(OCCc3ccc(F)cc3)cc2)OC(=O)C1.Cc1nc(C)c([C@H](OC(C)(C)C)C(=O)OC(C)C)c(N2CCC(C(F)(F)F)CC2)c1Br>>Cc1nc(C)c([C@H](OC(C)(C)C)C(=O)OC(C)C)c(N2CCC(C(F)(F)F)CC2)c1-c1ccc(OCCc2ccc(F)cc2)cc1 -US20140100231A1,1,CCOC(=O)C(Cl)C(C)=O.N#Cc1cc(O)cc(Cl)c1>>CCOC(=O)C(Oc1cc(Cl)cc(C#N)c1)C(C)=O -US20040014773A1,1,Clc1cc2[nH]nnc2c(Cl)n1.OCc1ccccc1>>Clc1cc2[nH]nnc2c(OCc2ccccc2)n1 -US20050065164A1,1,CC1(C)CN(Cc2ccccc2)CCC1=O.[NH4+]>>CC1(C)CN(Cc2ccccc2)CCC1N -US07329679B2,2,COC(=O)CCCCOc1cc2c(cc1N)nc(-c1ccccc1)n2-c1ccc(OC)cc1.O=S(=O)(O)c1ccc(Cl)cc1>>COC(=O)CCCCOc1cc2c(cc1NS(=O)(=O)c1ccc(Cl)cc1)nc(-c1ccccc1)n2-c1ccc(OC)cc1 -US08906889B2,1,C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC7(C6)CC(C(=O)OC)C7)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.O=S1(=O)CCN(CCCl)CC1>>C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC7(C6)CC(C(=O)OC)C7)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US04056537,6,CC1(CC(=O)O)OCCc2c1[nH]c1ccc(OCc3ccccc3)cc21>>CC1(CC(=O)O)OCCc2c1[nH]c1ccc(O)cc21 -US06022492,3,CCCCCCCCCCc1ccc(B(O)O)c(F)c1F.CCCCCCOc1ccc(-c2ncc(Br)cn2)cn1>>CCCCCCCCCCc1ccc(-c2cnc(-c3ccc(OCCCCCC)nc3)nc2)c(F)c1F -US20130310384A1,1,CC[C@H](NS(=O)(=O)c1ccc(C(=O)OC)cc1)c1ccccc1.N#Cc1ccc(CBr)cc1>>CC[C@@H](c1ccccc1)N(Cc1ccc(C#N)cc1)S(=O)(=O)c1ccc(C(=O)OC)cc1 -US20150259341A1,3,Brc1ccc2ncc(-c3ccccc3)n2c1.Cc1ccc(-n2nccc2B2OC(C)(C)C(C)(C)O2)cc1>>Cc1ccc(-n2nccc2-c2ccc3ncc(-c4ccccc4)n3c2)cc1 -US20020035120A1,1,C[O-].Cc1cc(Br)n2ccnc2c1>>COc1cc(C)cc2nccn12 -US08785468B2,6,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1cc(-c2ccncc2)ccc1OCc1ccccc1>>N[C@@H](Cc1ccccc1)C(=O)Nc1cc(-c2ccncc2)ccc1OCc1ccccc1 -US04266963,1,CC(C)(C)C(=O)CBr.Cc1nn(C)c(O)c1C(=O)c1ccc(Cl)cc1Cl>>Cc1nn(C)c(OCC(=O)C(C)(C)C)c1C(=O)c1ccc(Cl)cc1Cl -US20130303524A1,2,NCc1ccco1.O=S(=O)(Cl)C1CCCCC1>>O=S(=O)(NCc1ccco1)C1CCCCC1 -US07989475B2,2,Nc1nnn[nH]1.O=C(O)c1ccc(Cn2nc(C3CCCCC3)cc2-c2ccc(OC(F)(F)F)cc2)cc1>>O=C(Nc1nnn[nH]1)c1ccc(Cn2nc(C3CCCCC3)cc2-c2ccc(OC(F)(F)F)cc2)cc1 -US04324790,1,C1=C(c2c[nH]c3ccccc23)CCNC1.ClCCOC1CCCCO1>>C1=C(c2c[nH]c3ccccc23)CCN(CCOC2CCCCO2)C1 -US20120157428A1,9,Cc1noc2c1-c1ccccc1C(c1ccc(Cl)cc1)=NC2N=[N+]=[N-]>>Cc1noc2c1-c1ccccc1C(c1ccc(Cl)cc1)=NC2N -US20090093474A1,2,CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1-c1ccc(C(=O)O)cc1Cl)CC2.CN[C@@H]1CC[C@H](N2CCCC2)CC1>>CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1-c1ccc(C(=O)N(C)[C@@H]3CC[C@H](N4CCCC4)CC3)cc1Cl)CC2 -US20130053572A1,1,C=O.CCCCC/C=C\C/C=C\CCCCCCCCOC(OCCCCCCCC/C=C\C/C=C\CCCCC)[C@H]1CCCN1>>CCCCC/C=C\C/C=C\CCCCCCCCOC(OCCCCCCCC/C=C\C/C=C\CCCCC)[C@H]1CCCN1C -US06900336B2,6,CCOC(=O)CCCCCCN1C(=O)CC[C@@H]1CCC(O)c1ccc(-c2ccccc2C)o1>>Cc1ccccc1-c1ccc(C(O)CC[C@H]2CCC(=O)N2CCCCCCC(=O)O)o1 -US07332497B2,3,CN1CCC(n2nc(I)c3c(N)ncnc32)CC1.Cc1cc(C)c2oc(Nc3ccc(B4OC(C)(C)C(C)(C)O4)cc3)nc2c1>>Cc1cc(C)c2oc(Nc3ccc(-c4nn(C5CCN(C)CC5)c5ncnc(N)c45)cc3)nc2c1 -US20090124596A1,1,CN.O=C(N[C@H]1CC[C@@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(OCCCl)cc4)c3)c2=O)CC1)c1cn2cc(F)ccc2n1>>CNCCOc1ccc(-c2cccc(-n3c(=O)n([C@@H]4CC[C@H](NC(=O)c5cn6cc(F)ccc6n5)CC4)c(=O)c4cc(F)cnc43)c2)cc1 -US08153626B2,7,Cc1ccc([N+](=O)[O-])c(N)n1>>Cc1ccc(N)c(N)n1 -US20120015905A1,4,COc1cc(N)c(C(N)=O)c(OC)c1.Cc1cc(C=O)cc(C)c1OCCN1CCOCC1>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCN4CCOCC4)c(C)c3)nc2c1 -US04994569,2,O=C=Nc1ccc(Cl)cc1.OC1COC(c2ccccc2)=NC1c1ccccc1>>O=C(Nc1ccc(Cl)cc1)OC1COC(c2ccccc2)=NC1c1ccccc1 -US20150259341A1,3,CC1(C)OB(c2ccnn2-c2ccc(Cl)cc2)OC1(C)C.Fc1cc(Cl)ccc1-c1cnc2ccc(Br)cn12>>Fc1cc(Cl)ccc1-c1cnc2ccc(-c3ccnn3-c3ccc(Cl)cc3)cn12 -US05965555,1,CCCn1cnc2c1c(=O)[nH]c(=O)n2C.CCN(CC)CC#CC(C)(O)CCCCCl>>CCCn1cnc2c1c(=O)n(CCCCC(C)(O)C#CCN(CC)CC)c(=O)n2C -US09120749B2,3,CC1(C)OB(c2cc(F)c(O)c(Cl)c2)OC1(C)C.CN(C)CCOc1ccc(Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)cn1>>CN(C)CCOc1ccc(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)cn1 -US20150018328A1,3,C=CB1OB(C=C)OB(C=C)O1.C[C@@H](Nc1nc(N[C@H](C)C2CC2)nc(-c2cccc(Cl)n2)n1)C1CC1>>C=Cc1cccc(-c2nc(N[C@H](C)C3CC3)nc(N[C@H](C)C3CC3)n2)n1 -US20120040942A1,9,CC(NC(=O)OC(C)(C)C)c1ccc(C(=O)C(F)(F)F)cc1.NO>>CC(NC(=O)OC(C)(C)C)c1ccc(C(=NO)C(F)(F)F)cc1 -US20130296312A1,1,CN(c1ccccc1CN)S(C)(=O)=O.Clc1nc2c(Br)cccn2n1>>CN(c1ccccc1CNc1cccn2nc(Cl)nc12)S(C)(=O)=O -US06432950B1,1,FC(F)(F)c1cc2c(NCc3ccc(Cl)c(Cl)c3)nc(Cl)nc2s1.c1nc[nH]n1>>FC(F)(F)c1cc2c(NCc3ccc(Cl)c(Cl)c3)nc(-n3cncn3)nc2s1 -US20080312214A1,6,CC(C)(C)[Si](C)(C)OC1CCCC(NC(=O)OCc2ccccc2)CCC1>>O=C(NC1CCCC(O)CCC1)OCc1ccccc1 -US20100197703A1,1,COc1ccc(S(=O)(=O)N2CCNCC2)cc1.N#CCBr>>COc1ccc(S(=O)(=O)N2CCN(CC#N)CC2)cc1 -US20140371201A1,2,CCOC(=O)/C=C/c1cc(SCc2ccccc2)ccc1Nc1cc(F)c(Br)cc1C>>Cc1cc(Br)c(F)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21 -US08344135B2,2,CC(=O)Nc1nc2cnc(Nc3cc(N)ccc3C)nc2s1.O=C(O)c1cccc(C(F)(F)F)c1Cl>>CC(=O)Nc1nc2cnc(Nc3cc(NC(=O)c4cccc(C(F)(F)F)c4Cl)ccc3C)nc2s1 -US04598090,1,ClCCN1CCOCC1.O=c1c2c(oc3cc(O)ccc13)C(=Cc1ccccc1)CC2>>O=c1c2c(oc3cc(OCCN4CCOCC4)ccc13)C(=Cc1ccccc1)CC2 -US20150018343A1,1,CC(C)(C)OC(=O)N1CC(O)C1.O=Cc1ccccc1F>>CC(C)(C)OC(=O)N1CC(Oc2ccccc2C=O)C1 -US20040039200A1,1,Fc1cc2cc[nH]c2cc1Cl.NCCCl>>NCCn1ccc2cc(F)c(Cl)cc21 -US07749530B2,1,CN1CCN(c2ccc(N)cc2)CC1.Cn1nc(C(C)(C)C)cc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CO)c1>>CN1CCN(c2ccc(NC=C3C(=O)Nc4cc(C(=O)c5cccc(NC(=O)c6cc(C(C)(C)C)nn6C)c5)ccc43)cc2)CC1 -US08173682B2,2,CCc1cc(-c2ccc(S(=O)(=O)Cl)s2)c(C)[nH]c1=O.NCCCN1CCCC1=O>>CCc1cc(-c2ccc(S(=O)(=O)NCCCN3CCCC3=O)s2)c(C)[nH]c1=O -US20100056509A1,3,C#CC(C)(C)O.O=[N+]([O-])c1cc(Cl)cnc1Br>>CC(C)(O)C#Cc1ncc(Cl)cc1[N+](=O)[O-] -US06248739B1,2,CCOC(=O)c1cn(C2CC2)c2ccc(I)cc2c1=O.NCc1ccc(Cl)cc1>>O=C(NCc1ccc(Cl)cc1)c1cn(C2CC2)c2ccc(I)cc2c1=O -US07560558B2,3,COc1cc2nccc(Oc3ccc(C)cc3Br)c2cc1OC.O=C(Cl)C1CCCCC1>>COc1cc2nccc(Oc3ccc(C)cc3C(=O)C3CCCCC3)c2cc1OC -US20150111885A1,3,COc1ccc(COc2cc(Br)cc(S(C)(=O)=O)c2)cc1.Cn1cc(B2OC(C)(C)C(C)(C)O2)c2ccoc2c1=O>>COc1ccc(COc2cc(-c3cn(C)c(=O)c4occc34)cc(S(C)(=O)=O)c2)cc1 -US20150274704A1,1,CC(C)(C)OC(=O)N1CC2CC(Nc3nc(Cl)ncc3Cl)CC2C1.Nc1cc(C2CC2)[nH]n1>>CC(C)(C)OC(=O)N1CC2CC(Nc3nc(Nc4cc(C5CC5)[nH]n4)ncc3Cl)CC2C1 -US20110159019A1,9,CC(C)(C)OC(=O)N[C@@H]1C[C@@H](CN=[N+]=[N-])C1>>CC(C)(C)OC(=O)N[C@@H]1C[C@@H](CN)C1 -US20130116234A1,1,CCNC.CCOC(=O)c1c(OS(=O)(=O)C(F)(F)F)nc2c(F)cc(Cl)cc2c1Cc1ccccc1Cl>>CCOC(=O)c1c(N(C)CC)nc2c(F)cc(Cl)cc2c1Cc1ccccc1Cl -US07888352B2,2,CN(C)CC(=O)O.Nc1ncc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)cn1>>CN(C)CC(=O)N1CCN(Cc2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)CC1 -US20120214808A1,2,Nc1ccc(N2CCc3ccccc3C2)c(F)c1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)Nc1ccc(N2CCc3ccccc3C2)c(F)c1 -US20100298384A1,2,COC(=O)[C@@H](N)CO.O=C(Nc1ccc(C(=O)O)c(F)c1)OCc1ccccc1>>COC(=O)C(CO)NC(=O)c1ccc(NC(=O)OCc2ccccc2)cc1F -US20090111867A1,6,Cc1noc(C)c1CN1N=C(c2c(C)n(CC(=O)OC(C)(C)C)c3ccc(F)cc23)c2ccccc2S1(=O)=O>>Cc1noc(C)c1CN1N=C(c2c(C)n(CC(=O)O)c3ccc(F)cc23)c2ccccc2S1(=O)=O -US20090247526A1,1,COc1cccc(Oc2ccnc(Cl)c2)c1.Cc1csc(N)n1>>COc1cccc(Oc2ccnc(Nc3nc(C)cs3)c2)c1 -US20090149466A1,1,O=Cc1ccccc1O.O=c1cc(N2CCNCC2)nc[nH]1>>O=c1cc(N2CCN(Cc3ccccc3O)CC2)nc[nH]1 -US20140128383A1,8,OCc1sc2ncccc2c1Br>>O=Cc1sc2ncccc2c1Br -US05472949,2,CC(=O)O[C@@H]1[C@@H](C)O[C@@H](n2cc(F)c(N)nc2=O)[C@@H]1OC(C)=O.CC(C)(C)COC(=O)Cl>>CC(=O)O[C@@H]1[C@@H](C)O[C@@H](n2cc(F)c(NC(=O)OCC(C)(C)C)nc2=O)[C@@H]1OC(C)=O -US08791083B2,8,CC(=O)OC1C(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C(CO)OC1n1ccc(=O)[nH]c1=O>>CC(=O)OC1C(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C(C=O)OC1n1ccc(=O)[nH]c1=O -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1ccccn1>>FC(F)(F)c1cccc2c(-c3cccc(NCc4ccccn4)c3)c(Cc3ccccc3)cnc12 -US06521666B1,7,COC(=O)[C@H](Cc1ccc(-c2ccccc2OC)cc1)NC(=O)c1ccc([N+](=O)[O-])cc1Cl>>COC(=O)[C@H](Cc1ccc(-c2ccccc2OC)cc1)NC(=O)c1ccc(N)cc1Cl -US06429214B1,6,COC(=O)Cc1cc2ccc(OCCCN)cc2n(Cc2ccccc2)c1=O>>NCCCOc1ccc2cc(CC(=O)O)c(=O)n(Cc3ccccc3)c2c1 -US08415486B2,2,CC(=O)C(=O)O.CC(C(=O)NC(C(=O)N1CCC2NCC(COc3ccc(F)c(F)c3)C21)C(C)(C)C)N(C)C(=O)OC(C)(C)C>>CC(=O)C(=O)N1CC(COc2ccc(F)c(F)c2)C2C1CCN2C(=O)C(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)C(C)(C)C -US07732435B2,1,CC(C)c1oc2c(O)c(OCc3ccccc3)ccc2c(=O)c1-c1ccc(Cl)cc1.CI>>COc1c(OCc2ccccc2)ccc2c(=O)c(-c3ccc(Cl)cc3)c(C(C)C)oc12 -US20150152112A1,9,CCOC(=O)c1cc(Br)cs1.N#C[Cu]>>CCOC(=O)c1cc(C#N)cs1 -US07737166B2,1,CCOC(=O)CCCNc1nc2c(C#N)c(C)c(-c3ccccc3)c(F)c2o1.CN(C)[C@H]1CCNC1>>CCOC(=O)CCCNc1nc2c(C#N)c(C)c(-c3ccccc3)c(N3CC[C@H](N(C)C)C3)c2o1 -US20110028390A1,1,CC(=O)C=O.NNCc1ccccc1>>CC(=O)C=NNCc1ccccc1 -US20050137236A1,3,CC(C)(C)OC(=O)N(CCc1ccc(Br)cc1)C[C@H](O)c1ccccc1.COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1-c1cccs1>>COC(=O)c1ccc(-c2ccc(CCN(C[C@H](O)c3ccccc3)C(=O)OC(C)(C)C)cc2)cc1-c1cccs1 -US07732446B1,6,CCOC(=O)c1cnc(CNC(=O)OC(C)(C)C)c2c(OC)cc(OC)cc12>>COc1cc(OC)c2c(CNC(=O)OC(C)(C)C)ncc(C(=O)O)c2c1 -US05935972,3,CCCC[Sn](CCCC)(CCCC)c1cnnn1C.O=Cc1cc(Br)cc2ccoc12>>Cn1nncc1-c1cc(C=O)c2occc2c1 -US20140011130A1,7,C=C(C)C(=O)Nc1ccc([N+](=O)[O-])cc1>>C=C(C)C(=O)Nc1ccc(N)cc1 -US06071909,2,C1COCCN1.Cc1ccc2c(c1)ncn2-c1cccc(C(=O)O)c1>>Cc1ccc2c(c1)ncn2-c1cccc(C(=O)N2CCOCC2)c1 -US06444615B1,2,C#CCN1C(=O)COc2cc(F)c(N)cc21.CCCN=C=O>>C#CCN1C(=O)COc2cc(F)c(NC(=O)NCCC)cc21 -US20090227799A1,6,COCOc1cc(CNC(=O)c2cccnc2N)ccc1OCc1ccccc1>>Nc1ncccc1C(=O)NCc1ccc(OCc2ccccc2)c(O)c1 -US20080207708A1,3,CCOC(=O)c1nc(CBr)cs1.OB(O)c1cc(Cl)ccc1OCc1ccccc1>>CCOC(=O)c1nc(Cc2cc(Cl)ccc2OCc2ccccc2)cs1 -US20080300242A1,1,COc1cc(CCN2CCOCC2)c(F)cc1N.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>COc1cc(CCN2CCOCC2)c(F)cc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US20140349993A1,2,Cc1cc2ncc(C(=O)O)n2nc1-c1ccccc1C(F)(F)F.Nc1ccncc1>>Cc1cc2ncc(C(=O)Nc3ccncc3)n2nc1-c1ccccc1C(F)(F)F -US04827011,4,C=CC(C)(C)OCCCCCCCCCCCCCCCC.O=C(OO)c1cccc(Cl)c1>>CCCCCCCCCCCCCCCCOC(C)(C)C1CO1 -USRE045670E1,1,CCOC(=O)Cc1ccc(NC(=O)Nc2ncc(Br)s2)c(C(=O)C2CCCC2)c1.Sc1ccccn1>>CCOC(=O)Cc1ccc(NC(=O)Nc2ncc(Sc3ccccn3)s2)c(C(=O)C2CCCC2)c1 -US07544835B2,2,CC(C)OC(C(=O)N1C(=O)OCC1Cc1ccccc1)C(O)c1cccc(OCc2ccccc2)c1.CS(=O)(=O)Cl>>CC(C)O[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](OS(C)(=O)=O)c1cccc(OCc2ccccc2)c1 -US06677348B2,1,C#CCBr.Cc1nc2cnc3ccccc3c2n1CCCCO>>C#CCOCCCCn1c(C)nc2cnc3ccccc3c21 -US20110009428A1,6,CC(C)(C)OC(=O)Nc1ccc2c(Sc3ccccc3[N+](=O)[O-])cn(Cc3cc(F)cc(F)c3)c2c1>>Nc1ccc2c(Sc3ccccc3[N+](=O)[O-])cn(Cc3cc(F)cc(F)c3)c2c1 -US20110172209A1,1,O=C1CCCCC1Cl.c1ccc(COc2ccc3nc[nH]c3n2)cc1>>O=C1CCCCC1n1cnc2ccc(OCc3ccccc3)nc21 -US20040127492A1,4,CCOC(=O)C(=O)C1CCc2c(cnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)C1=O.NNCCO>>CCOC(=O)c1nn(CCO)c2c1CCc1c-2cnn1C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20090233879A1,6,Cc1cn(C2O[C@H](COC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(C)(O)[C@@]2(C)F)c(=O)[nH]c1=O>>Cc1cn(C2O[C@H](COC(=O)C(C)N)C(C)(O)[C@@]2(C)F)c(=O)[nH]c1=O -US04331683,3,CCC(=O)OC(=O)CC.O=Cc1cccc([N+](=O)[O-])c1>>CC(=Cc1cccc([N+](=O)[O-])c1)C(=O)O -US20150166564A1,2,Cc1c(-c2cnn(C)c2)nn(-c2ccccc2)c1N.O=C(Cl)Oc1ccccc1>>Cc1c(-c2cnn(C)c2)nn(-c2ccccc2)c1NC(=O)Oc1ccccc1 -US20150266859A1,2,CCCC(Nc1ccc(-n2cc(C(F)(F)F)cn2)cc1)c1ccc(C(=O)O)cc1.CCOC(=O)CCN>>CCCC(Nc1ccc(-n2cc(C(F)(F)F)cn2)cc1)c1ccc(C(=O)NCCC(=O)OCC)cc1 -US20070244125A1,1,CS(=O)(=O)Nc1ccc(B(O)O)cc1.O=C(c1ccc2[nH]c(C(=O)N3CCC(F)(F)CC3)cc2c1)N1CCN(C2CCC2)CC1>>CS(=O)(=O)Nc1ccc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(C(=O)N4CCN(C5CCC5)CC4)ccc32)cc1 -US20100298324A1,2,NCc1ccc(Cl)cc1.O=C(O)c1ccc2c(=O)n(-c3ncccn3)c(=S)[nH]c2c1>>O=C(NCc1ccc(Cl)cc1)c1ccc2c(=O)n(-c3ncccn3)c(=S)[nH]c2c1 -US20060287309A1,1,Cc1cc(=O)[nH]c2nc(OCCCC=O)ccc12.Clc1cccc(N2CCNCC2)c1Cl>>Cc1cc(=O)[nH]c2nc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)ccc12 -US08329725B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#Cc1ccc(S(=O)(=O)N2CCc3cc(Br)ccc32)cc1>>CC1(C)OB(c2ccc3c(c2)CCN3S(=O)(=O)c2ccc(C#N)cc2)OC1(C)C -US20100087432A1,1,COC(=O)CBr.N#Cc1c[nH]cc1-c1cc(Cl)cc(Cl)c1>>COC(=O)Cn1cc(C#N)c(-c2cc(Cl)cc(Cl)c2)c1 -US20110257151A1,1,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(Br)c1.O=c1[nH]cnc2c1CCN(Cc1ccccc1)C2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(-n2cnc3c(c2=O)CCN(Cc2ccccc2)C3)c1 -US07846956B2,7,COC(=O)c1cnn(C(C)(C)C)c1>>CC(C)(C)n1cc(CO)cn1 -US20040176602A1,1,C1COCCN1.COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(C=O)o4)ccc23)c(Cl)cc1Cl>>COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCOCC5)o4)ccc23)c(Cl)cc1Cl -US20120016029A1,1,CCOC(=O)Cc1ccc(OC)c(O)c1.O=Cc1cc(Br)ccc1F>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(Br)cc2C=O)c1 -US07417050B2,1,CCCC[Sn](Cl)(CCCC)CCCC.c1cscn1>>CCCC[Sn](CCCC)(CCCC)c1nccs1 -US20110046382A1,7,CCc1ccc(CCOc2ccc([N+](=O)[O-])cc2)nc1>>CCc1ccc(CCOc2ccc(N)cc2)nc1 -US20080132539A1,2,CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)OCc1ccccc1.Cc1cc(N)c(N)cc1C>>Cc1cc(N)c(NC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1C -US20110124633A1,3,CN(C)C=O.Cc1cccc2ccn(C)c12>>Cc1cccc2cc(C=O)n(C)c12 -US08377938B2,6,CN1CCN(C2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)C5(C(=O)OCc6ccccc6)CC5)c(F)c4)ccn3)CC2)CC1>>CN1CCN(C2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)C5(C(=O)O)CC5)c(F)c4)ccn3)CC2)CC1 -US20100035918A1,1,Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)[nH]c2=O)c1.O=[N+]([O-])c1cccc(CCl)c1>>Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)n(Cc3cccc([N+](=O)[O-])c3)c2=O)c1 -US08486953B2,2,Cc1c(C(=O)O)sc2ncnc(Nc3cccnc3OC3CCOCC3)c12.NCCN1CCCC1>>Cc1c(C(=O)NCCN2CCCC2)sc2ncnc(Nc3cccnc3OC3CCOCC3)c12 -US20060148799A1,1,C1CCNCC1.CN(C(=O)Oc1ccc(NC(=O)c2ccc(CCl)cc2)cc1)c1ccccc1>>CN(C(=O)Oc1ccc(NC(=O)c2ccc(CN3CCCCC3)cc2)cc1)c1ccccc1 -US20150080438A1,1,CNCCCCS(=O)CCCC(F)(F)C(F)(F)F.Oc1cccc(C2=C(CCCCCCBr)c3ccc(O)cc3CCC2)c1>>CN(CCCCCCC1=C(c2cccc(O)c2)CCCc2cc(O)ccc21)CCCCS(=O)CCCC(F)(F)C(F)(F)F -US20130116234A1,1,CCNC.N#Cc1c(Cl)nc2ccc(Cl)cc2c1-c1ccccc1>>CCN(C)c1nc2ccc(Cl)cc2c(-c2ccccc2)c1C#N -US20140005235A1,2,COC(=O)c1ccc(C(=O)O)c2ccccc12.Nc1c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1Cl>>COC(=O)c1ccc(C(=O)Nc2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Cl)c2ccccc12 -US05457205,6,COC(=O)COc1ccc(CC(C)N2CCOC(c3csc(C(F)(F)F)n3)C2)cc1>>CC(Cc1ccc(OCC(=O)O)cc1)N1CCOC(c2csc(C(F)(F)F)n2)C1 -US09108983B2,1,BrC1COC1.Brc1cn[nH]c1>>Brc1cnn(C2COC2)c1 -US20150274777A1,6,COC(=O)c1cc2ncccc2n1C>>Cn1c(C(=O)O)cc2ncccc21 -US20150239894A1,2,NC(=O)c1nn(CC(=O)O)c2ccc(Nc3cncnc3)cc12.O=C(Nc1cccc(-c2ccccc2Cl)c1F)[C@@H]1C[C@@H](F)CN1>>NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2ccc(Nc3cncnc3)cc12 -US20040192735A1,6,Cc1ccnc(C=Cc2nn(C3CCCCO3)c3cc(Nc4ccccc4C(=O)NCC#CCO)ccc23)c1>>Cc1ccnc(/C=C/c2n[nH]c3cc(Nc4ccccc4C(=O)NCC#CCO)ccc23)c1 -US20150025093A1,6,CCc1cc2c(N3CCC(NC(=O)OC(C)(C)C)CC3)ncnc2s1>>CCc1cc2c(N3CCC(N)CC3)ncnc2s1 -US20140121415A1,7,Nc1ccc([N+](=O)[O-])cc1C(=O)O>>Nc1ccc([N+](=O)[O-])cc1CO -US20130090323A1,3,CCS(=O)(=O)c1ccc(B(O)O)cc1.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1Br>>CCS(=O)(=O)c1ccc(-c2cnc(N3CCOCC3)cc2Nc2c(C)c(-c3ccccn3)nc3cc(F)cc(F)c23)cc1 -US20140179733A1,7,Cc1nc(C(F)(F)F)c2n1C(C(=O)Nc1cnn(-c3ccc(Cl)cc3)c1C(C)C)CC=C2>>Cc1nc(C(F)(F)F)c2n1C(C(=O)Nc1cnn(-c3ccc(Cl)cc3)c1C(C)C)CCC2 -US20030100772A1,6,CCOC(=O)C=CC1(c2ccc(OC)c3c2OCCO3)CCC2(CC1)OCCO2>>CCOC(=O)C=CC1(c2ccc(OC)c3c2OCCO3)CCC(=O)CC1 -US08551999B2,6,Cn1c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc2cc(Oc3ccc(NC(=O)c4ccc(C(F)(F)F)cc4)cn3)ccc21>>Cn1c(C(=O)N2CCNCC2)cc2cc(Oc3ccc(NC(=O)c4ccc(C(F)(F)F)cc4)cn3)ccc21 -US20090298823A1,1,Clc1nc(Cl)c2cc[nH]c2n1.NC(=O)C1CCNCC1>>NC(=O)C1CCN(c2nc(Cl)nc3[nH]ccc23)CC1 -US20090306133A1,2,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1.Nc1sc2ccccc2c1C(=O)O>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2c(N)sc3ccccc23)CC1 -US20150087639A1,1,C1COCCN1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>O=[N+]([O-])c1ccc(N2CCOCC2)c(Cl)c1 -US08530461B2,1,CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(Br)cc2)s1.COCCOc1ccc(OC2CNC2)cc1>>COCCOc1ccc(OC2CN(c3ccc([C@H](C)NC(=O)c4sc(NC(C)=O)nc4C)cc3)C2)cc1 -US05441950,6,CCOC(=O)CNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21>>O=C(O)CNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 -US20080280946A1,2,COC(=O)c1ccc2[nH]c(C(=O)O)cc2n1.NC1CCN(c2ccncc2)CC1>>COC(=O)c1ccc2[nH]c(C(=O)NC3CCN(c4ccncc4)CC3)cc2n1 -US20080300242A1,1,COc1cc(F)c(C)cc1[N+](=O)[O-].CS(=O)(=O)CCC1CCNCC1>>COc1cc(N2CCC(CCS(C)(=O)=O)CC2)c(C)cc1[N+](=O)[O-] -US07300952B2,6,CCOC(=O)c1c(NC(=O)OC(C)(C)C)sc2cc(-c3ccc(F)cc3)ccc12>>CC(C)(C)OC(=O)Nc1sc2cc(-c3ccc(F)cc3)ccc2c1C(=O)O -US20130225524A1,2,CCOC(=O)c1cccc(Nc2c(C(=O)O)cnc3cc(-c4c(C)noc4C)ccc23)c1.COc1ccc(CN)cc1>>CCOC(=O)c1cccc(Nc2c(C(=O)NCc3ccc(OC)cc3)cnc3cc(-c4c(C)noc4C)ccc23)c1 -US20050014812A1,7,CCCCCOc1cnc(C(=O)OCC)c(Cl)c1>>CCCCCOc1cnc(CO)c(Cl)c1 -US04187232,2,CC(C)C(=O)Cl.COC(=O)c1cc(C)sc1N>>COC(=O)c1cc(C)sc1NC(=O)C(C)C -US20040259857A1,6,COC(=O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1>>O=C(O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1 -US05250688,9,CC(=O)OCC(CCn1cnc2c(Cl)nc(N)nc21)COC(C)=O>>CC(=O)OCC(CCn1cnc2cnc(N)nc21)COC(C)=O -US20100173889A1,3,C1CCNC1.O=C1CCN(Cc2ccccc2)CC1.[C-]#N>>N#CC1(N2CCCC2)CCN(Cc2ccccc2)CC1 -US20100056524A1,6,CC(C)(C)OC(=O)NCCCNC(=O)C1CCC1>>NCCCNC(=O)C1CCC1 -US20070179143A1,7,COC(=O)c1cccc(CC=O)c1>>COC(=O)c1cccc(CCO)c1 -US04488971,1,NN.O=C(c1ccccc1)c1ccccc1>>NN=C(c1ccccc1)c1ccccc1 -US20060199817A1,3,CC(C)NC(=O)[C@H]1CCC(C)N1c1nncc2cc(Br)ccc12.Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(N3C(C)CC[C@@H]3C(=O)NC(C)C)nncc2c1 -US06018046,6,COc1cc2c(=O)c(C)cn3c4cc(Br)ccc4c(c1)c23>>Cc1cn2c3cc(Br)ccc3c3cc(O)cc(c1=O)c32 -US08093265B2,6,CC(=O)OC[C@@H](C)n1ccc2c(C(=O)NCC3(O)CCCCCC3)c(Cl)ccc2c1=O>>C[C@H](CO)n1ccc2c(C(=O)NCC3(O)CCCCCC3)c(Cl)ccc2c1=O -US06034275,10,Cc1ccc(-c2ccc(C(=O)c3ccc(Br)cc3)s2)cc1.O=C1CCC(=O)N1Br>>O=C(c1ccc(Br)cc1)c1ccc(-c2ccc(CBr)cc2)s1 -US20140329929A1,1,ClCc1ccccn1.O=S([O-])c1ccccc1>>O=S(=O)(Cc1ccccn1)c1ccccc1 -US20100130468A1,3,CC1CC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC(C)S1(=O)=O.OB(O)c1ccsc1>>CC1CC(c2c[nH]c3c(C(N)=O)cc(-c4ccsc4)cc23)CC(C)S1(=O)=O -US20020077491A1,7,CCOC(=O)CC(C(=O)OCC)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)CC(C(=O)OCC)c1ccc(N)cc1 -US20040116469A1,7,CC[C@H](NC(=O)c1c(CN2CCC(=O)CC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1>>CC[C@H](NC(=O)c1c(CN2CCC(O)CC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1 -US04202697,6,CCC(=O)c1ccc(NC(C)=O)cc1>>CCC(=O)c1ccc(N)cc1 -US20080027070A1,2,Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C(=O)O.Nc1cnc(Nc2ccc(S(=O)(=O)CCCN3CCCC3)cc2)nc1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cnc(Nc2ccc(S(=O)(=O)CCCN3CCCC3)cc2)nc1 -US06395732B1,1,Cc1nc(C)c(Cl)c(NCc2nccc(SCCOCCCl)c2C)n1.Cc1ncc([N+](=O)[O-])[nH]1>>Cc1nc(C)c(Cl)c(NCc2nccc(SCCOCCn3c([N+](=O)[O-])cnc3C)c2C)n1 -US20130158031A1,6,C[Si](C)(C)C#Cc1ccc(-c2c[nH]nc2-c2ccncc2)cc1>>C#Cc1ccc(-c2c[nH]nc2-c2ccncc2)cc1 -US20110034483A1,3,COc1ccc(C(Cc2ccc(Br)cc2)c2cn(C)c(N)n2)cc1.OB(O)c1ccsc1>>COc1ccc(C(Cc2ccc(-c3ccsc3)cc2)c2cn(C)c(N)n2)cc1 -US07820823B2,9,[N-]=[N+]=NC[C@H]1CN(c2ccc(NC3CCN(C(=O)OCc4ccccc4)CC3)c(F)c2)C(=O)O1>>NC[C@H]1CN(c2ccc(NC3CCN(C(=O)OCc4ccccc4)CC3)c(F)c2)C(=O)O1 -US07572809B2,1,Cc1cc(Nc2cc3c(C)cccc3c(Cl)n2)n[nH]1.Oc1ccccc1>>Cc1cc(Nc2cc3c(C)cccc3c(Oc3ccccc3)n2)n[nH]1 -US07737169B2,6,CCOC(=O)C(Oc1cccc2c1ccn2C(=O)OCc1ccccc1)C(=O)OCC>>CCOC(=O)C(Oc1cccc2[nH]ccc12)C(=O)OCC -US08119627B2,7,O=[N+]([O-])c1ccccc1Sc1ccncc1>>Nc1ccccc1Sc1ccncc1 -US04283414,1,CC(C)C(C(=O)[O-])c1ccc(Cl)cc1.FC(Br)c1cccc(Oc2ccccc2)c1>>CC(C)C(C(=O)OC(F)c1cccc(Oc2ccccc2)c1)c1ccc(Cl)cc1 -US06362174B1,1,CC(C)(C)OC(=O)N[C@H](C=O)Cc1ccc(OCc2ccccc2)cc1.CCNCC>>CCN(CC)C[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C -US20030105137A1,2,Cn1c(CCc2ccc(C#N)cc2)nc2cc(NCc3cccc4ccccc34)ccc21.O=C(Cl)CCl>>Cn1c(CCc2ccc(C#N)cc2)nc2cc(N(Cc3cccc4ccccc34)C(=O)CCl)ccc21 -US20100120739A1,6,Cc1cc2ncccc2cc1CC(=O)OC(C)(C)C>>Cc1cc2ncccc2cc1CC(=O)O -US20150119405A1,2,C=CC(=O)Cl.COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@@H]4CCCC[C@@H]4N)ncc3c2)c1Cl>>C=CC(=O)N[C@H]1CCCC[C@@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1 -US20150133505A1,3,C#Cc1ccccc1.O=C1C[C@H]2CCC[C@H]2N1c1ccc(I)cn1>>O=C1C[C@H]2CCC[C@H]2N1c1ccc(C#Cc2ccccc2)cn1 -US08242130B2,3,C#Cc1ccc(OC)cc1.O=Cc1ccccc1Br>>COc1ccc(C#Cc2ccccc2C=O)cc1 -US07279580B2,3,CC(C)(O)c1ccn2c(-c3ccc(F)c(Cl)c3)cnc2c1F.CCOc1ccccc1B(O)O>>CCOc1ccccc1-c1cc(-c2cnc3c(F)c(C(C)(C)O)ccn23)ccc1F -US06713508B2,1,BrCCCOCc1ccccc1.CCOC(=O)C1CCc2ccc(O)cc2O1>>CCOC(=O)C1CCc2ccc(OCCCOCc3ccccc3)cc2O1 -US05218117,7,COc1cc2c(cc1OC)C(=C(C#N)SCC(CN1CCOCC1)OC(C)=O)NCC2>>COc1cc2c(cc1OC)C(=C(C#N)SCC(O)CN1CCOCC1)NCC2 -US03993683,1,CC(Cl)c1ccc(-c2ccccc2Cl)cc1.COC(=O)CS>>COC(=O)CSC(C)c1ccc(-c2ccccc2Cl)cc1 -US06350755B1,6,COc1cccc(S(=O)(=O)NCCC(=O)N2CCc3ncn(C)c3C2c2ccc(C#N)c(F)c2)c1>>Cn1cnc2c1C(c1ccc(C#N)c(F)c1)N(C(=O)CCNS(=O)(=O)c1cccc(O)c1)CC2 -US20120316147A1,1,CC(C)(C)C=O.CC(C)(C)S(N)=O>>CC(C)(C)/C=N/S(=O)C(C)(C)C -US05354749,10,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1CCC(=O)N1Br>>O=S(=O)(Cl)c1ccc(CBr)cc1 -US08263588B2,1,Cc1cccc(OCCCBr)c1N>>Cc1cccc2c1NCCCO2 -US05420126,8,CC1(C)CN(Cc2ccccn2)c2cc([N+](=O)[O-])ccc2O1.O=C(OO)c1cccc(Cl)c1>>CC1(C)CN(Cc2cccc[n+]2[O-])c2cc([N+](=O)[O-])ccc2O1 -US20150094296A1,9,CC(C)(CI)n1cc([N+](=O)[O-])cn1.[N-]=[N+]=[N-]>>CC(C)(CN=[N+]=[N-])n1cc([N+](=O)[O-])cn1 -US07098212B2,6,C[C@H]1CN(C(=O)COc2ccc(Cl)cc2CN2C(=O)c3ccccc3C2=O)[C@H](C)CN1Cc1ccc(F)cc1>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2CN)[C@H](C)CN1Cc1ccc(F)cc1 -US05686449,2,CCOC(=O)C(N)C(=O)OCC.O=C(Cl)OCc1ccccc1>>CCOC(=O)C(NC(=O)OCc1ccccc1)C(=O)OCC -US20030149200A1,3,Brc1cccc2c1CC=C2.CC(C)[Mg+]>>CC(C)c1cccc2c1CC=C2 -US04235930,6,CC#CCC(C)(C)[C@@H](/C=C/[C@H]1CCC(=O)[C@@H]1C/C=C\CCCC(=O)O)OC1CCCCO1>>CC#CCC(C)(C)[C@H](O)/C=C/[C@H]1CCC(=O)[C@@H]1C/C=C\CCCC(=O)O -US20140163012A1,6,CC(C)(C)OC(=O)N1CCCc2oc3cc(-n4ccc(OCc5ccc(C(F)(F)F)nc5)cc4=O)ccc3c2C1>>O=c1cc(OCc2ccc(C(F)(F)F)nc2)ccn1-c1ccc2c3c(oc2c1)CCCNC3 -US20040044012A1,1,COc1cc(N)cc(OC)c1.CSc1ncc(C=O)c(N)n1>>COc1cc(NCc2cnc(SC)nc2N)cc(OC)c1 -US20120184540A1,2,CNOC.O=C(O)c1nn(C(F)F)cc1Cl>>CON(C)C(=O)c1nn(C(F)F)cc1Cl -US04237300,7,O=[N+]([O-])c1cnc2ccc(Sc3ccccc3)cn12>>Nc1cnc2ccc(Sc3ccccc3)cn12 -US20080214495A1,7,Cn1nc(C2=CCN(C(=O)OC(C)(C)C)CC2)ccc1=O>>Cn1nc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1=O -US05710275,7,CC(=O)OC1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]32)C1>>CC(=O)OC1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CCC(O)[C@@]4(C)CC[C@@H]32)C1 -US07560558B2,3,COc1cc2nccc(Oc3ccc(C)nc3I)c2cc1OC.Cc1cccc(B(O)O)c1>>COc1cc2nccc(Oc3ccc(C)nc3-c3cccc(C)c3)c2cc1OC -US20070249593A1,3,CC1(C)CC=C(B(O)O)CC1.CN1CC(c2ccc(N)c(Br)c2)CN(C)C1=NC#N>>CN1CC(c2ccc(N)c(C3=CCC(C)(C)CC3)c2)CN(C)C1=NC#N -US20130137709A1,1,CNC(=O)c1ccccc1NC.Clc1ncc(Cl)c(Cl)n1>>CNC(=O)c1ccccc1N(C)c1nc(Cl)ncc1Cl -US08865744B1,2,CC(C)(C#N)c1nnc(N)s1.CN(CC1CCOCC1)C(C)(C)C(=O)O>>CN(CC1CCOCC1)C(C)(C)C(=O)Nc1nnc(C(C)(C)C#N)s1 -US20020165241A1,6,C[Si](C)(C)C#Cc1cnc(NCC2CCN(C(=O)[C@@H]3C[C@H]3c3ccccc3)CC2)nc1>>C#Cc1cnc(NCC2CCN(C(=O)[C@@H]3C[C@H]3c3ccccc3)CC2)nc1 -US20090286778A1,1,CC(C)(C)OC(=O)Nc1cc(CCc2cccc(N)c2)ccn1.Clc1ncc(Cl)c(Cl)n1>>CC(C)(C)OC(=O)Nc1cc(CCc2cccc(Nc3nc(Cl)ncc3Cl)c2)ccn1 -US03957782,1,CCn1ncc2nc(C(=O)O)c(-c3ccccc3)nc21.N#CCCl>>CCn1ncc2nc(C(=O)OCC#N)c(-c3ccccc3)nc21 -US04729998,7,COC(=O)c1cccc2cc[nH]c12>>COC(=O)c1cccc2c1NCC2 -US20150094297A1,7,COC(=O)c1csc(N(C)CCC#N)n1>>CN(CCC#N)c1nc(CO)cs1 -US07550495B2,4,CC(=O)N(C)c1ccc(NCC2CCOCC2)c(N)c1.O=C(O)C(F)(F)F>>CC(=O)N(C)c1ccc2c(c1)nc(C(F)(F)F)n2CC1CCOCC1 -US04897477,6,COC(=O)C1=C2Nc3ccccc3C23CCN(Cc2ccccc2)C3C(CC(C)(C)CO[Si](C)(C)C(C)(C)C)C1>>COC(=O)C1=C2Nc3ccccc3C23CCN(Cc2ccccc2)C3C(CC(C)(C)CO)C1 -US20140206663A1,7,C=Cc1cn(C2(C)CN(C(=O)OC(C)(C)C)C2)c2cc3c(cc12)OCC1=NNC(=O)[C@@H](C)N13>>CCc1cn(C2(C)CN(C(=O)OC(C)(C)C)C2)c2cc3c(cc12)OCC1=NNC(=O)[C@@H](C)N13 -US05506234,9,COCc1c(C=O)ncc2[nH]c3cccc(Cc4ccc(Cl)cc4)c3c12.NO>>COCc1c(C=NO)ncc2[nH]c3cccc(Cc4ccc(Cl)cc4)c3c12 -US07517991B2,2,NCC1CCN(S(=O)(=O)c2cccc3ccccc23)CC1.O=C(Cl)C1CCCCC1>>O=C(NCC1CCN(S(=O)(=O)c2cccc3ccccc23)CC1)C1CCCCC1 -US20140336377A1,2,COc1cc(C(C)N)cnc1OCC(F)(F)F.Nc1nccc(C(=O)O)n1>>COc1cc(C(C)NC(=O)c2ccnc(N)n2)cnc1OCC(F)(F)F -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.COC(=O)c1nn(-c2cccc(Br)c2)c2cc(C)ncc12>>COC(=O)c1nn(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)c2cc(C)ncc12 -US05098900,9,COc1ccc(CNc2cnn(C(C)C)c(=O)c2Cl)c(OC)c1>>COc1ccc(CNc2cnn(C(C)C)c(=O)c2)c(OC)c1 -US07132425B2,1,COCCN.O=[N+]([O-])c1cnc(Br)cn1>>COCCNc1cnc([N+](=O)[O-])cn1 -US20050113346A1,2,CCOC(=O)CN.O=S(=O)(Cl)c1ccc(F)cc1>>CCOC(=O)CNS(=O)(=O)c1ccc(F)cc1 -US04072696,7,CCCCOc1ccc(N)c([N+](=O)[O-])c1>>CCCCOc1ccc(N)c(N)c1 -US05021428,1,BrCCc1ccccc1.O=C(c1ccccc1)C1CCNCC1>>O=C(c1ccccc1)C1CCN(CCc2ccccc2)CC1 -US20040063691A1,2,CCCCc1c(C(=O)Cl)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1.NN1CCCCC1>>CCCCc1c(C(=O)NN2CCCCC2)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 -US08492591B2,6,CC(C)(C)OC(=O)NC[C@@H]1C[C@H]1c1cc(F)ccc1OCC1CC1>>NC[C@@H]1C[C@H]1c1cc(F)ccc1OCC1CC1 -US20060229312A1,2,CC(=O)O.Cc1ccc2c(N3CCN(CC(C)c4cccc(N)c4)CC3)cccc2n1>>CC(=O)Nc1cccc(C(C)CN2CCN(c3cccc4nc(C)ccc34)CC2)c1 -US07632875B2,5,CC(C)(Br)C(=O)Oc1ccc(N)cc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)Nc1ccc(OC(=O)C(C)(C)Br)cc1 -US03940394,1,CCOC(=O)CSc1nc(Cl)cc(Cl)n1.Cc1cc(C)c(N)c(C)c1>>CCOC(=O)CSc1nc(Cl)cc(Nc2c(C)cc(C)cc2C)n1 -US06359134B1,2,CC(C)(C)OC(=O)N1CCNCC1.CC(C)N(CCc1ccc(C(=O)O)cc1)C(C)C>>CC(C)N(CCc1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1)C(C)C -US07329764B2,7,CCOc1ccc(C(=O)O)c(F)c1C#N>>CCOc1ccc(CO)c(F)c1C#N -US07393868B2,3,CC(C)S(=O)(=O)Nc1ccsc1-c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.COC(=O)c1cccc([N+](=O)[O-])c1Br>>COC(=O)c1cccc([N+](=O)[O-])c1-c1ccc(-c2sccc2NS(=O)(=O)C(C)C)cc1 -US07749530B2,1,CCn1nc(C)cc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CO)c1.Nc1ccc(N2CCOCC2)cc1>>CCn1nc(C)cc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CNc2ccc(N3CCOCC3)cc2)c1 -US05606054,9,NO.O=C1CCCc2cccnc21>>ON=C1CCCc2cccnc21 -US08022206B2,3,CC(C)(C)N1CC=C([Sn](C)(C)C)CC1.C[C@@H](Oc1c(N)ncc2c(Br)coc12)c1c(Cl)ccc(F)c1Cl>>C[C@@H](Oc1c(N)ncc2c(C3=CCN(C(C)(C)C)CC3)coc12)c1c(Cl)ccc(F)c1Cl -US20030092712A1,2,COc1ccc(CNCc2c(Br)cc([N+](=O)[O-])cc2Br)cc1.O=C=Nc1c(Cl)cccc1Cl>>COc1ccc(CN(Cc2c(Br)cc([N+](=O)[O-])cc2Br)C(=O)Nc2c(Cl)cccc2Cl)cc1 -US05525742,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(N)cc(Cl)c1>>CC(C)(C)OC(=O)Nc1cc(N)cc(Cl)c1 -US06051570,7,Nc1cc(N2CCCCC2)c(F)cc1[N+](=O)[O-]>>Nc1cc(F)c(N2CCCCC2)cc1N -US20080125460A1,3,COc1ccnc(CCc2nc3cc(I)cnc3[nH]2)c1.OB(O)c1ccc2[nH]ccc2c1>>COc1ccnc(CCc2nc3cc(-c4ccc5[nH]ccc5c4)cnc3[nH]2)c1 -US20070265345A1,3,O=[N+]([O-])c1ccc(Br)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>O=[N+]([O-])c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US07528163B2,2,CCCCNCCC.COc1ccc2c(C(=O)C(C)(C)C)nn(CC(=O)O)c2c1>>CCCCN(CCC)C(=O)Cn1nc(C(=O)C(C)(C)C)c2ccc(OC)cc21 -US20090048251A1,2,C1CCNC1.COC(=O)[C@H](C)Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12>>C[C@H](Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12)C(=O)N1CCCC1 -US04978761,8,CC(=O)Oc1c(C)c(C)c2c(c1C)CC(C)(CO)O2>>CC(=O)Oc1c(C)c(C)c2c(c1C)CC(C)(C=O)O2 -US20130281657A1,2,C[C@H](N)C(=O)N[C@@H](C)C(=O)OC(C)(C)C.O=Cc1cnc(NCC(=O)O)s1>>C[C@H](NC(=O)CNc1ncc(C=O)s1)C(=O)N[C@@H](C)C(=O)OC(C)(C)C -US07727988B2,1,COC(CCBr)OC.Cc1nc(C)c(-c2c[nH]c(=O)[nH]c2=O)o1>>COC(CCn1cc(-c2oc(C)nc2C)c(=O)[nH]c1=O)OC -US20120270865A2,2,CCOC(=O)CCN.Cc1c(C(Nc2ccc(C(=O)O)cc2)C2CCCCC2)oc2cccnc12>>CCOC(=O)CCNC(=O)c1ccc(NC(c2oc3cccnc3c2C)C2CCCCC2)cc1 -US20100210642A1,1,Nc1cc(Cl)c(C(F)(F)F)cc1[N+](=O)[O-].OCC(F)(F)F>>Nc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1[N+](=O)[O-] -US20110178064A1,3,C[C@H]1CN(c2ncc(Br)cc2C=O)C[C@@H](C)O1.OB(O)c1cccc2cccnc12>>C[C@H]1CN(c2ncc(-c3cccc4cccnc34)cc2C=O)C[C@@H](C)O1 -US05942511,1,C=CCSc1ccc(Cl)nn1.Cc1cccc(O)c1>>C=CCSc1ccc(Oc2cccc(C)c2)nn1 -US05498611,2,CCOC(=O)c1nccc2c(C)c3c(cc12)c1cc(O)ccc1n3C.NCCN1CCCC1>>Cc1c2ccnc(C(=O)NCCN3CCCC3)c2cc2c3cc(O)ccc3n(C)c12 -US20100120784A1,1,CCOC(=O)Cn1nnc(-c2cc(O)no2)n1.OCC1(COc2cc(F)ccc2Br)CC1>>CCOC(=O)Cn1nnc(-c2cc(OCC3(COc4cc(F)ccc4Br)CC3)no2)n1 -US20100204207A1,2,CC(C)OC(=O)Cl.Cc1cc(I)c(N)cc1C(F)(F)F>>Cc1cc(I)c(NC(=O)OC(C)C)cc1C(F)(F)F -US09067922B2,1,COc1ccc(CN)c(OC)c1.Fc1ccc(F)nc1>>COc1ccc(CNc2ccc(F)cn2)c(OC)c1 -US20060276518A1,2,COC(=O)[C@@H](N)Cc1ccc(-c2ccccc2Oc2ccccc2)cc1.Nc1ccc(Cl)cc1C(=O)O>>COC(=O)[C@H](Cc1ccc(-c2ccccc2Oc2ccccc2)cc1)NC(=O)c1cc(Cl)ccc1N -US20130252986A1,1,N#Cc1ccc(F)cn1.Oc1ccc(Cl)c(C(F)(F)F)c1>>N#Cc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cn1 -US05840732,1,ClCCCCBr.Sc1cccc2nccn12>>ClCCCCSc1cccc2nccn12 -US20090176774A1,1,CNC(=O)c1cc(Cl)ccn1.Nc1cccc2cc(O)ccc12>>CNC(=O)c1cc(Oc2ccc3c(N)cccc3c2)ccn1 -US20100190814A1,2,CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)NS(C)(=O)=O.COCCOC(=O)Cl>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)N(C(=O)OCCOC)c1cc(Cl)ccc12)C(=O)NS(C)(=O)=O -US20120225854A1,1,C1CN[C@H](C2CC2)CN1.OC(c1ccc(Br)cc1)(C(F)(F)F)C(F)(F)F>>OC(c1ccc(N2CCN[C@H](C3CC3)C2)cc1)(C(F)(F)F)C(F)(F)F -US20060063779A1,2,NCc1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cc1.O=C(O)c1ccccn1>>O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(CNC(=O)c2ccccn2)cc1 -US20120208852A1,4,C[Si](C)(C)N=[N+]=[N-].N#C[C@H](NC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)c1cccc(C(F)(F)F)c1>>O=C(Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)NC(c1cccc(C(F)(F)F)c1)c1nnn[nH]1 -US20060234997A1,1,CN1CCc2ccc(O)cc2NC1=O.ClCCCCBr>>CN1CCc2ccc(OCCCCCl)cc2NC1=O -US20040097733A1,1,CC=O.CCOC(=O)c1ccc(Nc2ccc3c(c2)C(C)(C)CC=C3C(C)C)cc1>>CCOC(=O)c1ccc(N(CC)c2ccc3c(c2)C(C)(C)CC=C3C(C)C)cc1 -US04336269,2,CC(C)CCN.O=C(Cl)CCCc1ccc([N+](=O)[O-])cc1>>CC(C)CCNC(=O)CCCc1ccc([N+](=O)[O-])cc1 -US08642538B2,3,COC(=O)c1ccc(F)cc1Br.O=[N+]([O-])c1ccc(F)cc1Br>>COC(=O)c1ccc(F)cc1-c1cc(F)ccc1[N+](=O)[O-] -US04528287,1,CC(C)n1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21.CC1CNCCN1>>CC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C(C)C)c3c2F)CCN1 -US20100267666A1,3,CC(C)(CCCC#N)C(=O)c1c[nH]c2ncc(Br)nc12.COc1cc(B(O)O)cc(OC)c1OC>>COc1cc(-c2cnc3[nH]cc(C(=O)C(C)(C)CCCC#N)c3n2)cc(OC)c1OC -US04957914,2,CN.O=C(O)C1CCc2ccccc21>>CNC(=O)C1CCc2ccccc21 -US20110288104A1,6,COc1ccc(S(=O)(=O)N2CCN(C[C@H](O)COc3ccc(OCc4ccccc4)cc3)CC2)cc1>>COc1ccc(S(=O)(=O)N2CCN(C[C@H](O)COc3ccc(O)cc3)CC2)cc1 -US20150284335A1,6,COC(=O)c1nc2cc(NC(=O)c3ccccc3)ccc2[nH]1>>O=C(Nc1ccc2[nH]c(C(=O)O)nc2c1)c1ccccc1 -US20080119466A1,1,CNC(=O)c1ccc2[nH]ccc2c1.O=[N+]([O-])c1ccc(F)cc1>>CNC(=O)c1ccc2c(ccn2-c2ccc([N+](=O)[O-])cc2)c1 -US20100196502A1,2,Nc1nc(-c2ccccc2[N+](=O)[O-])cs1.O=C(O)CCCCCCC(=O)NOCc1ccccc1>>O=C(CCCCCCC(=O)Nc1nc(-c2ccccc2[N+](=O)[O-])cs1)NOCc1ccccc1 -US20110275797A1,1,COC(=O)c1ccc(O)cc1O.CS(=O)(=O)OC1CCN(S(C)(=O)=O)CC1>>COC(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1O -US20100075973A1,1,CC[C@@H]1c2c(C#N)ncn2-c2cnc(Cl)nc2N1C1CCCC1.COc1cc(C(=O)O)ccc1N>>CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3ccc(C(=O)O)cc3OC)nc2N1C1CCCC1 -US20080255358A1,1,Cc1nc2c(Br)cc(Br)cn2c1C.c1nc[nH]n1>>Cc1nc2c(-n3cncn3)cc(Br)cn2c1C -US20090221579A1,3,CN1C(=O)CC(C)(c2cccc(Br)c2)N=C1N.COc1cccc(B(O)O)c1>>COc1cccc(-c2cccc(C3(C)CC(=O)N(C)C(N)=N3)c2)c1 -US05102878,9,NO.O=Cc1c(-c2ccccc2)nn2ccccc12>>ON=Cc1c(-c2ccccc2)nn2ccccc12 -US20140114067A1,2,Nc1ccccc1I.O=C(O)Cc1ccc(Cl)c(Cl)c1>>O=C(Cc1ccc(Cl)c(Cl)c1)Nc1ccccc1I -US07098221B2,2,CN(C)CCOC(c1ccccc1)c1ccc(C(=O)Cl)cc1.Cc1nc(N)c2ncn(CCCCN)c2c1C>>Cc1nc(N)c2ncn(CCCCNC(=O)c3ccc(C(OCCN(C)C)c4ccccc4)cc3)c2c1C -US20080004268A1,2,CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)O)c(-c4cccnc4)c3c2)cc1.NC1CCOCC1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)NC4CCOCC4)c(-c4cccnc4)c3c2)cc1 -US20140275013A1,4,Cc1cnc(N)c(N)c1.O=C(O)c1cc(Br)ccc1Cl>>Cc1cnc2nc(-c3cc(Br)ccc3Cl)[nH]c2c1 -US20130190347A1,2,CCOC(=O)CCn1c2c(c3cc(C)ccc31)CN(C)CC2.CN>>CNC(=O)CCn1c2c(c3cc(C)ccc31)CN(C)CC2 -US20050187228A1,2,Cc1ccc(S(=O)(=O)O)cc1.NCCNc1nc(Cl)nc2c1ncn2C1CCCC1>>Cc1ccc(S(=O)(=O)NCCNc2nc(Cl)nc3c2ncn3C2CCCC2)cc1 -US06720342B2,3,Brc1ccsc1.C#CCO>>OCC#Cc1ccsc1 -US20110124636A1,2,NC[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)c1nc(N)sc1-c1cccc(F)c1.O=C(O)c1cccc2cnccc12>>Nc1nc(C(=O)N2[C@H](CNC(=O)c3cccc4cnccc34)C[C@@H]3C[C@@H]32)c(-c2cccc(F)c2)s1 -US06458814B1,7,CCOC(=O)CC(Cc1nc(C(=O)O)co1)c1ccccc1>>CCOC(=O)CC(Cc1nc(CO)co1)c1ccccc1 -US20100041892A1,7,CCOC(=O)/C=C/c1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl>>COCCOc1ccc(/C=C/CO)c(Oc2ncc(C(F)(F)F)cc2Cl)c1 -US20100256356A1,6,COc1ccc(Cn2nc(NC3CCN(C(=O)OC(C)(C)C)C3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(NC3CCNC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1 -US20070232627A1,7,CCOC(=O)C(C)(N)c1cccs1>>CC(N)(CO)c1cccs1 -US20140249145A1,6,CCOC(=O)c1cnn2c(C)cc(C)nc12>>Cc1cc(C)n2ncc(C(=O)O)c2n1 -US20020013466A1,6,Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3cccc(OCc4ccccc4)c3)c(Cl)cc2F)c1=O>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3cccc(O)c3)c(Cl)cc2F)c1=O -US07265123B2,2,NCCS(=O)(=O)c1ccccc1.O=C(O)C=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1>>O=C(C=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1)NCCS(=O)(=O)c1ccccc1 -US20050261324A1,1,CC(C)=O.Nc1cncnc1>>CC(C)Nc1cncnc1 -US20100055071A1,3,CC1(C)OB(c2ccc(NC(=O)C3CC3)cc2)OC1(C)C.O=C(OCc1ccccc1)N1CCCC1c1ccc(Br)cc1>>O=C(Nc1ccc(-c2ccc(C3CCCN3C(=O)OCc3ccccc3)cc2)cc1)C1CC1 -US05441955,6,CC(C)(C)OC(=O)N1CCN(c2ccc3c(c2)-n2c(nc4ccccc4c2=O)C3=O)CC1>>O=C1c2ccc(N3CCNCC3)cc2-n2c1nc1ccccc1c2=O -US20110224155A1,3,C/C=C/B(O)O.N#Cc1cc(Br)ccc1NS(N)(=O)=O>>C/C=C/c1ccc(NS(N)(=O)=O)c(C#N)c1 -US20130296312A1,1,CC(C)(C)OC(=O)N1CCC(CNc2cccn3nc(Cl)nc23)C1.CN1CCN(c2ccc(N)cc2)CC1>>CN1CCN(c2ccc(Nc3nc4c(NCC5CCN(C(=O)OC(C)(C)C)C5)cccn4n3)cc2)CC1 -US20050059658A1,7,CCC1(C)CC(=O)NN=C1c1ccc(C)c([N+](=O)[O-])c1>>CCC1(C)CC(=O)NN=C1c1ccc(C)c(N)c1 -US05843942,6,CS(=O)(=O)c1ccc(OCc2ccccc2)c(C2OCCO2)c1>>CS(=O)(=O)c1ccc(OCc2ccccc2)c(C=O)c1 -US07723337B2,2,COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1N1CCNCC1.C[C@@H](O)C(=O)O>>COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1N1CCN(C(=O)[C@@H](C)O)CC1 -US20130085148A1,3,Brc1nccs1.OB(O)c1ccc(F)cc1>>Fc1ccc(-c2nccs2)cc1 -US20130172318A1,2,Cc1cc(C)cc(C(=O)Cl)c1.NC1CCCNC1=O>>Cc1cc(C)cc(C(=O)NC2CCCNC2=O)c1 -US07230098B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCOC(=O)c1cc2cc(Br)ccc2[nH]1>>CCOC(=O)c1cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2[nH]1 -US20130158075A1,6,CC(C(=O)OC(C)(C)C)N1CCC(c2ncc(-c3ccc(NC(=O)Nc4ccccc4Cl)cc3)s2)CC1>>CC(C(=O)O)N1CCC(c2ncc(-c3ccc(NC(=O)Nc4ccccc4Cl)cc3)s2)CC1 -US08987461B2,7,COC(=O)c1ccc(I)cc1OC>>COc1cc(I)ccc1CO -US05274118,6,COC(=O)c1ccc(Cc2cn(C)c3ccc(C(=O)OC)cc23)c(OC)c1>>COC(=O)c1ccc2c(c1)c(Cc1ccc(C(=O)O)cc1OC)cn2C -US20100144760A1,3,Cc1ccc(B2OCC(C)(C)CO2)c(C#N)n1.Ic1cnccn1>>Cc1ccc(-c2cnccn2)c(C#N)n1 -US07781443B2,2,CC(=O)Cl.CCOC(=O)N1c2ccc(OC)nc2[C@@H](NC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ncc(N)cn2)C[C@H]1CC>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](NC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ncc(NC(C)=O)cn2)C[C@H]1CC -US20110172230A1,1,CNC1CCN(C(=O)Nc2cnccn2)CC1.Clc1nc(-c2ccccc2)ns1>>CN(c1nc(-c2ccccc2)ns1)C1CCN(C(=O)Nc2cnccn2)CC1 -US09108938B2,2,COc1ccc(C(CN)N2CCOCC2)cc1.Cc1ccccc1C(=O)O>>COc1ccc(C(CNC(=O)c2ccccc2C)N2CCOCC2)cc1 -US05268377,2,CCCCc1nc2c([nH]1)CC(C(=O)OC)NC2.O=C(Cl)OCc1ccccc1>>CCCCc1nc2c([nH]1)CC(C(=O)OC)N(C(=O)OCc1ccccc1)C2 -US20140213586A1,1,CN(C)c1ccc(C=O)cn1.COc1cccc(N)c1>>COc1cccc(N=Cc2ccc(N(C)C)nc2)c1 -US20040242572A1,2,COC(=O)c1cc(CCN)ccc1CN1CCCC1.O=C(O)c1ccc(-c2ccc(Cl)cc2)cc1>>COC(=O)c1cc(CCNC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)ccc1CN1CCCC1 -US20080312206A1,2,COC(=O)c1cc(N)ccc1Cl.O=C(Cl)c1cc(F)cc(C(F)(F)F)c1>>COC(=O)c1cc(NC(=O)c2cc(F)cc(C(F)(F)F)c2)ccc1Cl -US06384051B1,1,CCOc1cc2ncc(C#N)c(Cl)c2cc1OCC.NCc1ccc(F)c(F)c1>>CCOc1cc2ncc(C#N)c(NCc3ccc(F)c(F)c3)c2cc1OCC -US08324405B2,1,BrCc1ccccc1.CC1(C)OC(=O)c2c(O)cccc2O1>>CC1(C)OC(=O)c2c(OCc3ccccc3)cccc2O1 -US08586751B2,6,NC(=O)c1ccc(N2CCC[C@@H](NC(=O)c3ccccc3)C2)nc1Nc1ccc(N2CCN(C(=O)OCc3ccccc3)CC2)cc1>>NC(=O)c1ccc(N2CCC[C@@H](NC(=O)c3ccccc3)C2)nc1Nc1ccc(N2CCNCC2)cc1 -US05071988,6,COc1ccc(-c2ccc(C(C)=O)cc2[N+](=O)[O-])cc1>>CC(=O)c1ccc(-c2ccc(O)cc2)c([N+](=O)[O-])c1 -US06117893,7,CNc1nc(-c2ccccc2)ccc1[N+](=O)[O-]>>CNc1nc(-c2ccccc2)ccc1N -US20010031867A1,1,CCCCCCCCI.CCCCCCc1cc(-c2nc(-c3ccc(C(C)(C)C)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)c(O)cc1O>>CCCCCCCCOc1cc(O)c(-c2nc(-c3ccc(C(C)(C)C)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1CCCCCC -US20070060629A1,2,C[C@H](O)CN.Cc1onc(-c2ccccc2)c1-c1ccc(C(=O)O)c(Cl)c1>>Cc1onc(-c2ccccc2)c1-c1ccc(C(=O)NC[C@H](C)O)c(Cl)c1 -US06670379B2,1,CC(C)(C)OC(=O)N1[C@@H](C=O)COC1(C)C.O=C(c1ccc(F)cc1)C1CCNCC1>>CC(C)(C)OC(=O)N1[C@@H](CN2CCC(C(=O)c3ccc(F)cc3)CC2)COC1(C)C -US08044068B2,1,CS(=O)(=O)C1CCN(c2cc(Cl)nc3ccsc23)CC1.N[C@H]1CCN(C(=O)Cc2ccc(OC(F)(F)F)cc2)C1>>CS(=O)(=O)C1CCN(c2cc(N[C@H]3CCN(C(=O)Cc4ccc(OC(F)(F)F)cc4)C3)nc3ccsc23)CC1 -US20090221555A1,1,CCN1C(=O)CCC(C)(C)c2ccc(N)cc21.CS(=O)(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl>>CCN1C(=O)CCC(C)(C)c2ccc(Nc3ncc(Cl)c(Nc4c(F)cccc4S(C)(=O)=O)n3)cc21 -US04990508,6,CCOC(=O)c1cn([C@@H](C)CN(C)C(=O)OC(C)(C)C)c2c(F)c(C3(NC(=O)OCc4ccccc4)CC3)c(F)cc2c1=O>>CCOC(=O)c1cn([C@@H](C)CNC)c2c(F)c(C3(NC(=O)OCc4ccccc4)CC3)c(F)cc2c1=O -US20130059853A1,1,CC(C)CBr.COc1c(OC(F)F)ccc(Br)c1O>>COc1c(OC(F)F)ccc(Br)c1OCC(C)C -US07776867B2,2,CCN1CCNCC1.O=C(Cl)c1ccc(I)cc1>>CCN1CCN(C(=O)c2ccc(I)cc2)CC1 -US06294527B1,7,CSc1cc(=O)c2ccc(C(=O)O)cc2s1>>CSc1cc(=O)c2ccc(CO)cc2s1 -US06034239,9,CCC(=O)NCCC1=CCC2=C1C1=C(OCCC1)C(Br)C2>>CCC(=O)NCCC1=CCC2=C1C1=C(CC2)OCCC1 -US20030055064A1,1,CC(=O)NC1(c2ccc(CCl)cc2)CC1.c1ccc(N2CCNCC2)nc1>>CC(=O)NC1(c2ccc(CN3CCN(c4ccccn4)CC3)cc2)CC1 -US20070299092A1,1,COCCOc1cc2ncnc(NC3=CC(=O)C(Cl)=CC3=O)c2cc1OC.O=C(O)C1CNC1>>COCCOc1cc2ncnc(NC3=CC(=O)C(N4CC(C(=O)O)C4)=CC3=O)c2cc1OC -US20060009487A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cnc2ccccc2c1NCCCCN>>CCOC(=O)c1cnc2ccccc2c1NCCCCNC(=O)OC(C)(C)C -US20150087675A1,9,Cc1ccc(C(N=[N+]=[N-])C2CCSCC2)o1>>Cc1ccc(C(N)C2CCSCC2)o1 -US07087635B2,1,CC(C)(Cc1c[nH]c2c(O)cccc12)NC(=O)OC(C)(C)C.N#CCBr>>CC(C)(Cc1c[nH]c2c(OCC#N)cccc12)NC(=O)OC(C)(C)C -US20090137804A1,2,Nc1cc(Nc2ccc(N3CCOCC3)cc2)ncn1.O=C=Nc1c(F)cccc1F>>O=C(Nc1cc(Nc2ccc(N3CCOCC3)cc2)ncn1)Nc1c(F)cccc1F -US07696201B2,1,O=C1CC2CCC(C1)C2.O=C1Nc2ccccc2C2(CCNCC2)O1>>O=C1Nc2ccccc2C2(CCN(C3CC4CCC(C4)C3)CC2)O1 -US20110144056A1,1,Ic1cnn(C2CCCCO2)c1.Sc1ccc(Cl)cc1>>Clc1ccc(Sc2cnn(C3CCCCO3)c2)cc1 -US07531532B2,2,CN1CC(N2CCN(C(=O)Nc3cc(Oc4ccc(N)cc4F)ncn3)CC2)C1.O=C(Cc1ccc(F)cc1)N=C=S>>CN1CC(N2CCN(C(=O)Nc3cc(Oc4ccc(NC(=S)NC(=O)Cc5ccc(F)cc5)cc4F)ncn3)CC2)C1 -US06265426B1,1,COC(=O)c1ccc(O)c(F)c1.FC(F)Cl>>COC(=O)c1ccc(OC(F)F)c(F)c1 -US08809525B2,3,CC(C)c1cccc(B(O)O)c1.Nc1nnc(Br)c(-c2ccccc2)n1>>CC(C)c1cccc(-c2nnc(N)nc2-c2ccccc2)c1 -US06777442B2,8,O=S(=O)(c1ccc(F)cc1)c1cc(CO)ccc1OCc1ccccc1>>O=Cc1ccc(OCc2ccccc2)c(S(=O)(=O)c2ccc(F)cc2)c1 -US20120316161A1,3,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.COc1cc(Cl)ccc1B(O)O>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(Cl)cc1OC -US06541466B2,2,C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O.NN1C(=O)C(C2CCCCC2)c2ccccc2-c2ccccc21>>C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)NN1C(=O)C(C2CCCCC2)c2ccccc2-c2ccccc21 -US08143282B2,2,CCN(CC)CCn1c(CNC(=O)C(C)(C)C)nc2cc(C=CC(=O)OC)ccc21.NO>>CCN(CC)CCn1c(CNC(=O)C(C)(C)C)nc2cc(C=CC(=O)NO)ccc21 -US20040097733A1,7,COc1ccc(C(=O)CCC(=O)O)cc1C>>COc1ccc(CCCC(=O)O)cc1C -US07429609B2,6,CN(NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>CNNC(=O)OCc1ccccc1 -US20080076771A1,6,COc1ccc(CN(C(=O)OC(C)(C)C)c2nc(-c3cccc(OC(F)(F)F)c3)ns2)cc1>>CC(C)(C)OC(=O)Nc1nc(-c2cccc(OC(F)(F)F)c2)ns1 -US20070037807A1,6,COC(=O)Cc1ccc(OCc2c(C)nc(CC(C)C)c(CNC(=O)OC(C)(C)C)c2-c2ccc(C)cc2)cc1>>COC(=O)Cc1ccc(OCc2c(C)nc(CC(C)C)c(CN)c2-c2ccc(C)cc2)cc1 -US20150080438A1,1,CN.O=S(=O)(CCCCl)CCCC(F)(F)F>>CNCCCS(=O)(=O)CCCC(F)(F)F -US20030105115A1,7,CCOC([PH2]=O)(c1ccc([N+](=O)[O-])cc1)P(=O)(OCC)OCC>>CCOC([PH2]=O)(c1ccc(N)cc1)P(=O)(OCC)OCC -US20050090669A1,7,COC(=O)c1cc(Oc2ccc3c(c2)C[C@@H](N(C[C@H](O)c2cccc(Cl)c2)C(=O)OC(C)(C)C)CC3)cc([N+](=O)[O-])c1>>COC(=O)c1cc(N)cc(Oc2ccc3c(c2)C[C@@H](N(C[C@H](O)c2cccc(Cl)c2)C(=O)OC(C)(C)C)CC3)c1 -US06248755B1,1,BrCc1ccccc1.O=C(O)[C@@H](O)CC1CCC1>>O=C(OCc1ccccc1)[C@@H](O)CC1CCC1 -US20090226398A1,10,Cc1ccc(-c2ccc([N+](=O)[O-])cc2C(F)(F)F)nc1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1ccc(-c2ccc(CBr)cn2)c(C(F)(F)F)c1 -US20120232050A1,2,C#CC(C)(C)N.O=C(O)C1CC1>>C#CC(C)(C)NC(=O)C1CC1 -US08178522B2,2,Cc1nc(CCc2conc2-c2ccccn2)sc1C(=O)O.NC1CCOCC1>>Cc1nc(CCc2conc2-c2ccccn2)sc1C(=O)NC1CCOCC1 -US05246961,1,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](Br)SC[C@H]1OC(C)=O.O=[N+]([O-])c1ccccc1O>>CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2ccccc2[N+](=O)[O-])SC[C@H]1OC(C)=O -US20100298287A1,9,Cc1cc(C(N)=O)ccc1N.S=C(Cl)Cl>>Cc1cc(C(N)=O)ccc1N=C=S -US06218385B1,1,CC(C)(C)[Si](C)(C)OCCCCCl.Cc1nc(O)c([N+](=O)[O-])c(N2CCc3ccccc3CC2)n1>>Cc1nc(OCCCCO[Si](C)(C)C(C)(C)C)c([N+](=O)[O-])c(N2CCc3ccccc3CC2)n1 -US04873260,1,CI.COCC1C(=O)OC1CCCCC(C)CC(C)O>>COCC1C(=O)OC1CCCCC(C)CC(C)OC -US20090221555A1,2,CC(=O)OC(C)=O.O=C1CCNc2ccccc2CN1>>CC(=O)N1CCC(=O)NCc2ccccc21 -US20100168418A1,1,CCc1ccc(C=O)cc1.NC1CCN(CCn2c(=O)cnc3ccc(F)cc32)CC1>>CCc1ccc(CNC2CCN(CCn3c(=O)cnc4ccc(F)cc43)CC2)cc1 -US20060241127A1,8,O=C(OO)c1cccc(Cl)c1.c1cnc2[nH]ccc2c1>>[O-][n+]1cccc2cc[nH]c21 -US20090054407A1,1,CI.O=C(O)c1ccc2cc[nH]c2c1>>Cn1ccc2ccc(C(=O)O)cc21 -US08399674B2,1,COc1ccccc1CNc1ccc2cc(CN)ccc2n1.O=Cc1ccc(F)cc1>>COc1ccccc1CNc1ccc2cc(CNCc3ccc(F)cc3)ccc2n1 -US04861880,3,CN1CCCC1=O.O=C1Cc2ccc(Cl)cc2N1c1ccccc1>>CN1CCCC1=C1C(=O)N(c2ccccc2)c2cc(Cl)ccc21 -US20070167452A1,6,COCOc1ccc(C(=O)NC[C@H]2CC[C@@H](Oc3ccc(OC)cc3)CC2)cc1>>COc1ccc(O[C@@H]2CC[C@H](CNC(=O)c3ccc(O)cc3)CC2)cc1 -US20090209562A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.Cc1nc2ccc(Br)cc2c(=O)n1-c1ccc(OCCCN2CCCCC2)cc1>>Cc1nc2ccc(-c3ccccn3)cc2c(=O)n1-c1ccc(OCCCN2CCCCC2)cc1 -US20130237571A1,3,CCOC(=O)CCc1ccc(OC)cc1Br.Cc1noc(C)c1B(O)O>>CCOC(=O)CCc1ccc(OC)cc1-c1c(C)noc1C -US20100173888A1,2,CN1CCC(N)CC1.O=C(N[C@H]1CC[C@@H](C(=O)O)C1)c1ccc(-c2cccc(F)c2)nc1>>CN1CCC(NC(=O)[C@@H]2CC[C@H](NC(=O)c3ccc(-c4cccc(F)c4)nc3)C2)CC1 -US20070281917A1,2,C1CC2(CCN1)OCCO2.Cc1ccc(F)cc1S(=O)(=O)Cl>>Cc1ccc(F)cc1S(=O)(=O)N1CCC2(CC1)OCCO2 -US20030078415A1,2,CC(C)(C)OC[C@H]1O[C@](n2cnc3c(N)ncnc32)([SiH](c2ccccc2)c2ccccc2)[C@H](OCCO)[C@@H]1O.O=C(Cl)c1ccccc1>>CC(C)(C)OC[C@H]1O[C@](n2cnc3c(NC(=O)c4ccccc4)ncnc32)([SiH](c2ccccc2)c2ccccc2)[C@H](OCCO)[C@@H]1O -US20110124633A1,2,CNCc1sc2ccccc2c1C.O=C(O)/C=C/c1cnc2c(c1)CN1CCC[C@H]1C(=O)N2>>Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CN2CCC[C@H]2C(=O)N3)sc2ccccc12 -US20140249074A1,3,COC(=O)N1CC(=O)N2C(CCC2c2ncc(-c3ccc(Br)cc3)[nH]2)C1.COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(-c4cnc(C5CCC6CN(C(=O)OC)CC(=O)N65)[nH]4)cc3)cc2)[nH]1)C(C)C -US08063099B2,4,CC(N)=S.CCOC(=O)C(Cl)C(=O)c1cccc(F)c1>>CCOC(=O)c1sc(C)nc1-c1cccc(F)c1 -US06586441B2,1,N#Cc1c(Cl)nc(N)nc1OCc1ccccn1.OCc1ccccc1>>N#Cc1c(OCc2ccccc2)nc(N)nc1OCc1ccccn1 -US20150246063A1,2,CS(=O)(=O)Cl.OC1CCC(C(F)(F)F)CC1>>CS(=O)(=O)OC1CCC(C(F)(F)F)CC1 -US20040192708A1,6,Cn1c(N)c(NC(=O)Cc2ccc(NC(=O)OC(C)(C)C)cc2)c(=O)n(C)c1=O>>Cn1c(N)c(NC(=O)Cc2ccc(N)cc2)c(=O)n(C)c1=O -US20110060146A1,3,CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1.COC(=O)Cc1cccc(Br)c1>>CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(-c2cccc(CC(=O)OC)c2)c(C)c1 -US20100121052A1,7,C[C@@H](COc1cc(-c2cnn(C)c2)cc([N+](=O)[O-])c1)NC(=O)OC(C)(C)C>>C[C@@H](COc1cc(N)cc(-c2cnn(C)c2)c1)NC(=O)OC(C)(C)C -US20120052130A1,7,CC(C)(C)OC(=O)n1ccc2ncccc21>>CC(C)(C)OC(=O)N1CCc2ncccc21 -US20050014812A1,8,Cc1cc(CO)cc2c1nc(C)n2Cc1ccc(Cl)cc1Cl>>Cc1cc(C=O)cc2c1nc(C)n2Cc1ccc(Cl)cc1Cl -US08354444B2,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.COC(=O)c1ccc(CN)cc1>>COC(=O)c1ccc(CNC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1 -US08436043B2,2,CCOC(=O)CCNC.Cc1c(C(Nc2ccc(C(=O)O)cn2)C(C)C)oc2ccc(OCC3CC3)cc12>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(OCC4CC4)cc3c2C)C(C)C)nc1 -US20110009389A1,2,CC(=O)Cl.Cc1ncc2n1C(=O)N(C1CCN(C(=O)[C@H](N)CS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC1)C2>>CC(=O)N[C@H](CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C(=O)N1CCC(N2Cc3cnc(C)n3C2=O)CC1 -US08030354B2,6,COC(=O)c1ccc(OC2CCCCO2)c(C2=CCOCC2)c1>>COC(=O)c1ccc(O)c(C2=CCOCC2)c1 -US20130289274A1,6,COC(=O)c1ccc(CNC(=O)OC(C)(C)C)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)NCc1ccc(C(=O)O)c([N+](=O)[O-])c1 -US20100324030A1,1,COC(=O)CC1(N)CCN(C(=O)OCc2ccccc2)CC1.O=Cc1ccc2c(c1)OCCO2>>COC(=O)CC1(NCc2ccc3c(c2)OCCO3)CCN(C(=O)OCc2ccccc2)CC1 -US20100278833A1,1,COC(=O)c1sc(-n2cnc3cnccc32)cc1O.FC(F)(F)c1ccc(CBr)cc1>>COC(=O)c1sc(-n2cnc3cnccc32)cc1OCc1ccc(C(F)(F)F)cc1 -US08222248B2,2,Cc1ccc(N)cc1C.Nc1ccc(C(=O)O)cc1[N+](=O)[O-]>>Cc1ccc(NC(=O)c2ccc(N)c([N+](=O)[O-])c2)cc1C -US05326497,3,C=CC(C)OC(C)=O.CCOc1cnc(-c2ccc(Br)cc2)nc1>>CCOc1cnc(-c2ccc(C=CC(C)OC(C)=O)cc2)nc1 -US08664220B2,1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4N)cc3)cc2)CC1.O=S(c1ccccc1)c1cccc(Br)n1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cccc(S(=O)c5ccccc5)n4)cc3)cc2)CC1 -US20120289702A1,1,CC(=O)C(C)(C)c1c(O)cccc1F.Fc1ccc2cc(I)cnc2c1F>>CC(=O)C(C)(C)c1c(F)cccc1Oc1cnc2c(F)c(F)ccc2c1 -US20090118296A1,1,COC(=O)c1ccc(Cl)nn1.FC(F)(F)c1ccccc1O[C@H]1CCNC1>>COC(=O)c1ccc(N2CC[C@H](Oc3ccccc3C(F)(F)F)C2)nn1 -US20100130737A1,2,COC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1.O=C(O)c1nc2ccc(-c3ccc(Cl)cc3)cn2c1Cl>>COC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)c1nc2ccc(-c3ccc(Cl)cc3)cn2c1Cl -US04616086,2,CC(C)(C)c1cc(C=CC(=O)O)cc(C(C)(C)C)c1O.CCOC(=O)Cc1ccc(CCN2CCNCC2)cc1>>CCOC(=O)Cc1ccc(CCN2CCN(C(=O)C=Cc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)CC2)cc1 -US20110130380A1,9,CC1(C)CC(CNc2ccc(Cl)c(-c3cc(F)ncc3Cl)n2)CCO1.[NH4+]>>CC1(C)CC(CNc2ccc(Cl)c(-c3cc(N)ncc3Cl)n2)CCO1 -US20110112140A1,3,CC1(C)OB(c2ccoc2)OC1(C)C.O=C(O)NCc1cccc(Br)c1>>O=C(O)NCc1cccc(-c2ccoc2)c1 -US20090270447A1,1,C1CCNC1.N#Cc1ccc(Br)cc1>>N#Cc1ccc(N2CCCC2)cc1 -US08293757B2,7,CCN(CC)CCOc1ccc([N+](=O)[O-])cc1>>CCN(CC)CCOc1ccc(N)cc1 -US20110195986A1,10,Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)O.O=C1CCC(=O)N1Br>>O=C(O)c1sc(-c2ccc(Cl)cc2)nc1CBr -US04401598,9,CO[Si](OC)(OC)c1ccc(CCl)cc1.[N-]=[N+]=[N-]>>CO[Si](OC)(OC)c1ccc(CN=[N+]=[N-])cc1 -US20150094297A1,4,CC(C)(C(N)=S)c1ccccc1.CCOC(=O)C(=O)CBr>>CCOC(=O)c1csc(C(C)(C)c2ccccc2)n1 -US20070208033A1,1,COc1ccccc1C=O.NCCCCNC(=O)c1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1>>COc1ccccc1CNCCCCNC(=O)c1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1 -US04590201,10,Cc1cc(Cl)c(C(=O)c2ccccc2)c(Cl)c1.O=C1CCC(=O)N1Br>>O=C(c1ccccc1)c1c(Cl)cc(CBr)cc1Cl -US20060276447A1,6,CC(C)(C)OC(=O)NC1CN(c2ccc(C(F)(F)F)cn2)C1>>NC1CN(c2ccc(C(F)(F)F)cn2)C1 -US07498460B2,1,COC(=O)c1ccc(OCCCc2ccc(O)cc2)c(C(=O)NC2CCCC(C(=O)OC)C2)c1.ClCc1ccc(Oc2ccccc2)cc1>>COC(=O)c1ccc(OCCCc2ccc(OCc3ccc(Oc4ccccc4)cc3)cc2)c(C(=O)NC2CCCC(C(=O)OC)C2)c1 -US20050277676A1,9,N.O=C(O)c1cc(F)ccc1[N+](=O)[O-]>>NC(=O)c1cc(F)ccc1[N+](=O)[O-] -US20120172351A1,8,Cc1c(CO)cccc1-n1c([C@H]2CCCO2)nc2cc(OC(F)(F)F)ccc21>>Cc1c(C=O)cccc1-n1c([C@H]2CCCO2)nc2cc(OC(F)(F)F)ccc21 -US05468751,1,CCc1ncnc(NC(C)c2ccc3ccccc3c2)c1Br.C[S-]>>CCc1ncnc(NC(C)c2ccc3ccccc3c2)c1SC -US05807806,6,COC(OC)c1c(S(C)(=O)=O)ccc(C(=O)c2cnn(C)c2O)c1Cl>>Cn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(C=O)c2Cl)c1O -US20010049385A1,7,COC(=O)c1ccccc1Oc1ccccc1>>OCc1ccccc1Oc1ccccc1 -US20100081670A1,2,Nc1ncc(Cl)nc1Cl.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>O=S(=O)(Nc1ncc(Cl)nc1Cl)c1cccc(Cl)c1Cl -US04012515,3,C#CC(O)c1ccc(F)cc1.C=O.OC1(c2ccc(Cl)cc2)CCNCC1>>OC(C#CCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 -US20120046292A1,2,NCCNC(=O)c1ccc(Cl)cc1.O=C(O)c1ccc(O)cc1F>>O=C(NCCNC(=O)c1ccc(O)cc1F)c1ccc(Cl)cc1 -US07723368B2,6,C[Si](C)(C)C#Cc1ccc(F)c(OCCC(F)F)c1>>C#Cc1ccc(F)c(OCCC(F)F)c1 -US08394852B2,3,CC1=CC(=O)CO1.COc1cc(C=O)cc(OC)c1O>>COc1cc(C=C2OC(C)=CC2=O)cc(OC)c1O -US08618289B2,1,COc1cc2c(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)ncnc2cc1OCCCCl.O[C@@H]1CCNC1>>COc1cc2c(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)ncnc2cc1OCCCN1CC[C@@H](O)C1 -US06677369B2,6,CCOC(=O)Cc1ccc(NC(=O)c2cccc(C#N)c2)c(NC(=O)c2ccc(C(C)C)cc2)c1>>CC(C)c1ccc(C(=O)Nc2cc(CC(=O)O)ccc2NC(=O)c2cccc(C#N)c2)cc1 -US04973429,1,CCCCCCCCCCCCCCCCN.O=[N+]([O-])c1ccc(Cl)nc1>>CCCCCCCCCCCCCCCCNc1ccc([N+](=O)[O-])cn1 -US04029772,2,CCOC(=O)N(C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)N.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CCOC(=O)N(C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1 -US06972296B2,1,CCO.N#Cc1c(F)cccc1Cl>>CCOc1cccc(Cl)c1C#N -US07560558B2,1,CCO.COc1ccc(O)c(C(=O)O)c1>>CCOc1ccc(OC)cc1C(=O)O -US20120095034A1,1,FC(F)(F)CI.Nc1ncccc1O>>Nc1ncccc1OCC(F)(F)F -US05420271,2,CO.O=C(O)C1Cc2cscc2C1>>COC(=O)C1Cc2cscc2C1 -US20050136444A1,1,N=C(N)NN.O=Cc1cc(F)cc(C(F)(F)F)c1>>N=C(N)NN=Cc1cc(F)cc(C(F)(F)F)c1 -US05254558,6,CC(C)C(NC(=O)Cn1c(-c2ccc(F)cc2)ncc(N(C)C(=O)C(F)(F)F)c1=O)C(=O)C(F)(F)F>>CNc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(C(=O)C(F)(F)F)C(C)C)c1=O -US08088930B2,1,COC(=O)c1cc(F)c(O)c(F)c1.OCC(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21>>COC(=O)c1cc(F)c(OCC(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(F)c1 -US20050154042A1,7,COC(=O)C[C@H](O)C[C@H](O)C=Cc1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)NCc2ccc(F)cc2)n1C(C)C>>COC(=O)C[C@H](O)C[C@H](O)CCc1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)NCc2ccc(F)cc2)n1C(C)C -US20150099719A1,6,COC(=O)[C@@H]1CCCC[C@H]1c1oc(-c2ccc(F)cc2)nc1-c1ccc(Br)cc1>>O=C(O)[C@@H]1CCCC[C@H]1c1oc(-c2ccc(F)cc2)nc1-c1ccc(Br)cc1 -US09090599B2,2,COCCOc1ncc(C(=O)O)cc1-c1ccc(Cl)c(C)c1.NCc1nc(C(F)(F)F)no1>>COCCOc1ncc(C(=O)NCc2nc(C(F)(F)F)no2)cc1-c1ccc(Cl)c(C)c1 -US20120035164A1,3,Brc1ccc2c(c1)CNC2.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(B4OC(C)(C)C(C)(C)O4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc5c(c4)CNC5)cc23)CC1 -US05373008,1,CNC(=O)C(C)(C)C.Nc1ccccc1CN1CCOCC1>>CNC(=Nc1ccccc1CN1CCOCC1)C(C)(C)C -US20110301191A1,1,CN1CCC(=O)CC1.NCc1ccc(Cl)cc1>>CN1CCC(NCc2ccc(Cl)cc2)CC1 -US05153318,1,CCN.[N-]=[N+]=N[C@H]1C[C@H](n2cnc3c(Cl)nc(N)nc32)O[C@@H]1CO>>CCNc1nc(N)nc2c1ncn2[C@H]1C[C@H](N=[N+]=[N-])[C@@H](CO)O1 -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.COCC(C)(C)COc1cc(C)c(Br)c(C)c1>>COCC(C)(C)COc1cc(C)c(-c2ccc(F)c3c2CC[C@H]3Oc2ccc3c(c2)OC[C@H]3CC(=O)OC)c(C)c1 -US20050203104A1,7,CC(=O)c1ccc2c(c1)C(=C(NC1CCN(C)CC1)c1ccc([N+](=O)[O-])cc1)C(=O)N2C(C)=O>>CC(=O)c1ccc2c(c1)C(=C(NC1CCN(C)CC1)c1ccc(N)cc1)C(=O)N2C(C)=O -US08420640B2,7,Nc1cc(N2CCN(C(=O)c3ccccc3)CC2)ccc1[N+](=O)[O-]>>Nc1ccc(N2CCN(C(=O)c3ccccc3)CC2)cc1N -US20130289020A1,7,CC(C)(C)OC(=O)N1CCO[C@H](C(=O)O)C1>>CC(C)(C)OC(=O)N1CCO[C@H](CO)C1 -US20090227628A1,7,COC(=O)C/C=C/c1cccc2nc(NCc3ccc(C)o3)ccc12>>COC(=O)CCCc1cccc2nc(NCc3ccc(C)o3)ccc12 -US04523012,9,COC(=O)C(Cl)CSCc1ccccc1.[N-]=[N+]=[N-]>>COC(=O)C(CSCc1ccccc1)N=[N+]=[N-] -US06562989B2,3,O=Cc1ccc(Cl)cc1.OB(O)c1ccccc1>>O=Cc1ccc(-c2ccccc2)cc1 -US20150110863A1,2,CS(=O)(=O)Cl.[N-]=[N+]=NCCOCCO>>CS(=O)(=O)OCCOCCN=[N+]=[N-] -US20100197681A1,2,CN(C)Cc1ccc(C(=O)Cl)cc1.Nc1nc2cc(C(F)(F)F)cc(NC3CC3)n2n1>>CN(C)Cc1ccc(C(=O)Nc2nc3cc(C(F)(F)F)cc(NC4CC4)n3n2)cc1 -US07244722B2,2,COCCO.CS(=O)(=O)Cl>>COCCOS(C)(=O)=O -US06946478B2,6,COc1cccc(C(=O)NCCN2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)c1>>O=C(NCCN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1)c1cccc(O)c1 -US20150183801A1,3,COc1ccc(B(O)O)cn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1>>COc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N2CC[C@@H](O)C2)cn1 -US20110118230A1,1,COc1cc(-c2cnc(F)c(-c3cc(-c4cnn(C)c4)ncc3N)c2)cc(OC)c1CN1CCCCC1>>COc1cc(-c2cnc3[nH]c4cnc(-c5cnn(C)c5)cc4c3c2)cc(OC)c1CN1CCCCC1 -US20150152108A1,1,C[C@@H]1CNCCO1.O=C(Nc1cnccn1)N1c2nc(Cl)ccc2N2CC[C@H]1C2>>C[C@@H]1CN(c2ccc3c(n2)N(C(=O)Nc2cnccn2)[C@H]2CCN3C2)CCO1 -US08088760B2,9,COC(=O)c1cccc2nc(-c3ccc(CCN(C)C(=O)OCc4ccccc4)cc3)oc12.N>>CN(CCc1ccc(-c2nc3cccc(C(N)=O)c3o2)cc1)C(=O)OCc1ccccc1 -US04677212,2,CC1Cc2cccc(S(N)(=O)=O)c2OS1(=O)=O.CN=C=O>>CNC(=O)NS(=O)(=O)c1cccc2c1OS(=O)(=O)C(C)C2 -US20110237620A1,2,Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1F.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1F -US07223769B2,1,CC(C)C(C)O.Clc1cc(Cl)ncn1>>CC(C)C(C)Oc1cc(Cl)ncn1 -US05183492,1,C=CCBr.CCOC(=O)C(C)(C)OC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)ccc1Cl>>C=CCn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(C(=O)OC(C)(C)C(=O)OCC)c2)c1=O -US20140073620A1,6,CCC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2)ncc1C(F)(F)F>>CCC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCNCC3)cc2)ncc1C(F)(F)F -US20060258740A1,3,CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1Br.Cc1cccc(B(O)O)c1>>Cc1cccc(-c2ccccc2CCC(=O)N(NC(=O)c2ccccc2)C(C)C)c1 -US08399460B2,1,CC(Br)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCO[C@H](C)C3)oc12.Nc1ccc(F)cc1>>CC(Nc1ccc(F)cc1)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCO[C@H](C)C3)oc12 -US20140213586A1,3,Cn1ccc2ccccc21.O=C(Cl)Cc1ccccc1>>Cn1cc(C(=O)Cc2ccccc2)c2ccccc21 -US20080113961A1,1,CC(C)Cc1ccc(-c2cc(-c3csc(CO)c3)on2)cc1.CCOC(=O)C1CNC1>>CCOC(=O)C1CN(Cc2cc(-c3cc(-c4ccc(CC(C)C)cc4)no3)cs2)C1 -US20120134934A1,1,O=C(CBr)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(NS(=O)(=O)CC(F)(F)F)c1ccccc1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(NS(=O)(=O)CC(F)(F)F)c1ccccc1)C2)c1ccccc1 -US20120010186A1,6,CCOC(=O)Cn1nnc(-c2nnc(N3CC4CN(c5cc(F)ccc5Cl)CC4C3)s2)n1>>O=C(O)Cn1nnc(-c2nnc(N3CC4CN(c5cc(F)ccc5Cl)CC4C3)s2)n1 -US20110071147A1,2,CCOC(=O)c1cnc(N)c2c(COc3ccc(Br)cc3)csc12.NCCO>>Nc1ncc(C(=O)NCCO)c2scc(COc3ccc(Br)cc3)c12 -US20140141511A1,2,CCC(=O)Cl.COc1ccc([N+](=O)[O-])cc1N>>CCC(=O)Nc1cc([N+](=O)[O-])ccc1OC -US07585888B2,3,CC1(C)OB(c2ccc3c(N)c(C(=O)c4ccc(Cl)cc4Cl)oc3c2)OC1(C)C.Cc1ncccc1Br>>Cc1ncccc1-c1ccc2c(N)c(C(=O)c3ccc(Cl)cc3Cl)oc2c1 -US08415370B2,1,Cn1c(=O)oc2cc3c(cc21)OCC31C(=O)Nc2ccccc21.FC(F)(F)c1ccc(CBr)o1>>Cn1c(=O)oc2cc3c(cc21)OCC31C(=O)N(Cc2ccc(C(F)(F)F)o2)c2ccccc21 -US09115098B2,6,COC(=O)c1ccc(OCC(F)(F)C(F)(F)F)cn1>>O=C(O)c1ccc(OCC(F)(F)C(F)(F)F)cn1 -US20090253689A1,3,CC(C)COc1c(C#N)c(-c2ccc(Cl)cc2Cl)cn2c(Br)cnc12.OB(O)c1ccnc(F)c1>>CC(C)COc1c(C#N)c(-c2ccc(Cl)cc2Cl)cn2c(-c3ccnc(F)c3)cnc12 -US20080171743A1,3,CC1(C)OB(c2ccc(NC(=O)Nc3ccon3)cc2)OC1(C)C.C[C@H]1COCCN1c1cc(C(C)(C)O)nc(Cl)n1>>C[C@H]1COCCN1c1cc(C(C)(C)O)nc(-c2ccc(NC(=O)Nc3ccon3)cc2)n1 -US08207182B2,1,FC(F)(F)Oc1ccc(CBr)cc1.O=c1[nH]c2ccccc2[nH]1>>O=c1[nH]c2ccccc2n1Cc1ccc(OC(F)(F)F)cc1 -US20110230462A1,2,CC(C)N.C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cccc(C(=O)O)c3)nc12)C(=O)N1CC(C#N)C1>>CC(C)NC(=O)c1cccc(-c2cnc3c(n2)c(C(=O)N[C@H](C)C(=O)N2CC(C#N)C2)cn3COCC[Si](C)(C)C)c1 -US07375227B2,2,CNc1ccccc1.Cc1cc(NC(=O)NCCN2CCC(C(=O)O)CC2)c2ccccc2n1>>Cc1cc(NC(=O)NCCN2CCC(C(=O)N(C)c3ccccc3)CC2)c2ccccc2n1 -US20080312234A1,2,CS(=O)(=O)Nc1ccc(CN)cc1F.O=C(O)C=Cc1ccc(C(F)(F)F)nc1OCc1ccccc1>>CS(=O)(=O)Nc1ccc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2OCc2ccccc2)cc1F -US08022062B2,6,CC(C)(C)CC(=O)c1ccc(CNC(=O)OC(C)(C)C)cn1>>CC(C)(C)CC(=O)c1ccc(CN)cn1 -US20090227588A1,7,O=C(Nc1ccc([N+](=O)[O-])cn1)C1CCCCC1>>Nc1ccc(NC(=O)C2CCCCC2)nc1 -US04504660,1,N#Cc1c(F)cccc1F.Nc1ccccc1>>N#Cc1c(F)cccc1Nc1ccccc1 -US20070082912A1,6,COC(=O)c1cc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2c(F)cccc2F)cc(C(F)(F)F)c1>>Cc1ccc(-c2cc(Cl)ccc2OCc2c(F)cccc2F)n1-c1cc(C(=O)O)cc(C(F)(F)F)c1 -US07087605B2,2,CCC(N)c1nnc(C2CCCC2)[nH]c1=O.O=C(Cl)CC1CC2CCC1C2>>CCC(NC(=O)CC1CC2CCC1C2)c1nnc(C2CCCC2)[nH]c1=O -US06017929,8,O=C(OO)c1cccc(Cl)c1.O=C([C@@H]1CSCN1C(=O)CC1Cc2ccccc2C1)N1CCCC1>>O=C([C@@H]1CS(=O)CN1C(=O)CC1Cc2ccccc2C1)N1CCCC1 -US20090275566A1,3,C[C@@H]1C[C@@](C)(c2cccc(Br)c2)N=C(NC(=O)OC(C)(C)C)S1.OB(O)c1cncnc1>>C[C@@H]1C[C@@](C)(c2cccc(-c3cncnc3)c2)N=C(NC(=O)OC(C)(C)C)S1 -US05082467,1,O=[N+]([O-])c1cnc(Cl)c([N+](=O)[O-])c1.OCC(O)CO>>O=[N+]([O-])c1cnc(OCC(O)CO)c([N+](=O)[O-])c1 -US20070142432A1,1,COC(=O)CCCBr.Clc1ccc(Oc2ccc(O[C@@H]3CCNC3)cc2)cc1>>COC(=O)CCCN1CC[C@@H](Oc2ccc(Oc3ccc(Cl)cc3)cc2)C1 -US20120108577A1,1,N#Cc1ccc2c(c1)ncc(=O)n2CCN1CCC(N)CC1.O=Cc1ccc2c(n1)NC(=O)CO2>>N#Cc1ccc2c(c1)ncc(=O)n2CCN1CCC(NCc2ccc3c(n2)NC(=O)CO3)CC1 -US20070105919A1,1,C1COCCN1.O=C(Nc1nc(-c2ccco2)c(C(=O)c2ccccc2)s1)c1ccc(Cl)nc1>>O=C(Nc1nc(-c2ccco2)c(C(=O)c2ccccc2)s1)c1ccc(N2CCOCC2)nc1 -US20120289500A1,2,Nn1nc(N2CCOCC2)c2ccccc2c1=O.O=C(O)Cc1ccc(Oc2ccccc2)cc1>>O=C(Cc1ccc(Oc2ccccc2)cc1)Nn1nc(N2CCOCC2)c2ccccc2c1=O -US20020160996A1,2,Cc1c(C)c2c(c(C)c1N)C(c1ccc(C(C)C)cc1)C(C)(C)O2.O=C(Cl)c1ccccc1>>Cc1c(C)c2c(c(C)c1NC(=O)c1ccccc1)C(c1ccc(C(C)C)cc1)C(C)(C)O2 -US07109200B2,2,CCOC(=O)NC1(CN2CCNCC2=O)CCN(c2ccnc(C)c2)CC1.O=S(=O)(Cl)c1ccc(Br)cc1>>CCOC(=O)NC1(CN2CCN(S(=O)(=O)c3ccc(Br)cc3)CC2=O)CCN(c2ccnc(C)c2)CC1 -US05919779,3,Brc1cscc1Br.CCCC[Sn](CCCC)(CCCC)c1cccnc1F>>Fc1ncccc1-c1cscc1Br -US07709471B2,1,CCN1CCC(NC(=O)c2cc(OC)c(N)cc2F)CC1.CN1C(=O)C2(CC2)CN(C2CCCCC2)c2nc(Cl)ncc21>>CCN1CCC(NC(=O)c2cc(OC)c(Nc3ncc4c(n3)N(C3CCCCC3)CC3(CC3)C(=O)N4C)cc2F)CC1 -US20130158075A1,6,CCCCCc1ccc(C(=O)Nc2ccc(-c3cnc(CCCC(=O)OC)s3)cc2)cc1>>CCCCCc1ccc(C(=O)Nc2ccc(-c3cnc(CCCC(=O)O)s3)cc2)cc1 -US20110237553A1,1,CCOC(=O)c1ccc(O)cc1.OCCC12CC3CC(CC(C3)C1)C2>>CCOC(=O)c1ccc(OCCC23CC4CC(CC(C4)C2)C3)cc1 -US06448278B2,6,CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1 -US04129591,7,O=C(Nc1ccc2c(S(=O)(=O)O)cc(S(=O)(=O)O)cc2c1)c1cc(C(=O)Nc2ccc3c(S(=O)(=O)O)cc(S(=O)(=O)O)cc3c2)cc([N+](=O)[O-])c1>>Nc1cc(C(=O)Nc2ccc3c(S(=O)(=O)O)cc(S(=O)(=O)O)cc3c2)cc(C(=O)Nc2ccc3c(S(=O)(=O)O)cc(S(=O)(=O)O)cc3c2)c1 -US20090082372A1,2,COc1ccccc1C#Cc1ccc(OC(C)C)c(C(=O)O)c1.NC(CO)Cc1c[nH]c2ccncc12>>COc1ccccc1C#Cc1ccc(OC(C)C)c(C(=O)NC(CO)Cc2c[nH]c3ccncc23)c1 -US20110034469A1,6,CC(C)(C)OC(=O)N[C@H](C(=O)N1C[C@H]2CC(F)(F)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)c1ccccc1>>N[C@H](C(=O)N1C[C@H]2CC(F)(F)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)c1ccccc1 -US20120289522A1,2,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CCC(=O)O)cc3)cc2)CC1.NCC1CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CCC(=O)NCC4CC4)cc3)cc2)CC1 -US07067534B1,1,CCC(=O)Nc1cccc(C2CCNCC2)c1.ClCCCCCSc1ccccc1>>CCC(=O)Nc1cccc(C2CCN(CCCCCSc3ccccc3)CC2)c1 -US07449467B2,1,CC(C)[C@]1(C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)CC[C@@H](N)C1.COCC1COCCC1=O>>COCC1COCCC1N[C@@H]1CC[C@@](C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)(C(C)C)C1 -US04160838,1,COC(CBr)(OC)c1ccc(Cl)cc1Cl.c1nc[nH]n1>>COC(Cn1cncn1)(OC)c1ccc(Cl)cc1Cl -US07834190B2,1,CCC[C@@H](O)[C@@H](Cl)C(=O)OC>>CCC[C@H]1O[C@@H]1C(=O)OC -US20100075973A1,1,CCOC(=O)c1ncn2c1[C@@H](C)N(C1CCCC1)c1nc(Cl)ncc1-2.COc1cc(C(=O)O)ccc1N>>CCOC(=O)c1ncn2c1[C@@H](C)N(C1CCCC1)c1nc(Nc3ccc(C(=O)O)cc3OC)ncc1-2 -US20040102437A1,1,CCOC(=O)C1CCCCC1=O.Nc1ccc2[nH]ncc2c1>>CCOC(=O)C1CCCCC1Nc1ccc2[nH]ncc2c1 -US20020068828A1,1,Brc1ccc(Br)nc1.OCC(F)(F)F>>FC(F)(F)COc1ccc(Br)cn1 -US20020111492A1,1,COc1ccc2ncc(Cl)c(CCCC3(C(=O)OCc4ccccc4)CCNCC3)c2c1.Fc1cccc(F)c1OCCBr>>COc1ccc2ncc(Cl)c(CCCC3(C(=O)OCc4ccccc4)CCN(CCOc4c(F)cccc4F)CC3)c2c1 -US06407094B1,3,CC(C)(C)OCCOc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1I.OB(O)c1ccc(F)cc1>>CC(C)(C)OCCOc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1-c1ccc(F)cc1 -US08269008B2,2,CCOC(=O)c1nc(C#N)c2c(-c3cccs3)noc2c1O.NCC(=O)O>>N#Cc1nc(C(=O)NCC(=O)O)c(O)c2onc(-c3cccs3)c12 -US04584294,9,C=CCCC1C(=O)CCc2ccccc21.NO>>C=CCCC1C(=NO)CCc2ccccc21 -US20030220365A1,3,CC(C)(C)OC(=O)c1cc2c(C=O)cncc2s1.[Mg+]c1ccc(Cl)cc1>>CC(C)(C)OC(=O)c1cc2c(C(O)c3ccc(Cl)cc3)cncc2s1 -US20150141396A1,6,CCOC(=O)C1CCC(n2cc(-c3cnc(-c4cccc(-c5cnn(C)c5)c4)nc3)cn2)CC1>>Cn1cc(-c2cccc(-c3ncc(-c4cnn(C5CCC(C(=O)O)CC5)c4)cn3)c2)cn1 -US07332511B2,1,CC(=O)Nc1nc2c(O)cccc2s1.CC(C)(C)OC(=O)Nc1cc(C(F)(F)F)ccc1-c1cc(Cl)ncn1>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)OC(C)(C)C)ncn3)cccc2s1 -US20100267708A1,2,CN(C)C1CCNC1.O=C(O)C[C@@H]1CSC(c2cc3cc(Cl)cc(NC4CCCC4)c3[nH]2)=N1>>CN(C)C1CCN(C(=O)C[C@@H]2CSC(c3cc4cc(Cl)cc(NC5CCCC5)c4[nH]3)=N2)C1 -US06610747B2,7,CN(C)Cc1cc(/C=C/C(N)=O)ccc1Oc1ccc2c(c1)SCC2>>CN(C)Cc1cc(CCC(N)=O)ccc1Oc1ccc2c(c1)SCC2 -US07820699B2,2,CC(C)(C)OC(=O)N1C[C@H](O)[C@@H](N=[N+]=[N-])C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)O[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H]2N=[N+]=[N-])cc1 -US20090036492A1,6,COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(OC(C)=O)cc1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(O)cc1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US04028344,2,CC(C)(C)N=NC1(N=C=S)CCCCC1.NNC(N)=O>>CC(C)(C)N=NC1(NC(=S)NNC(N)=O)CCCCC1 -US04818761,4,CCNc1ccc(C)cc1N.O=C(O)CCl>>CCn1c(CCl)nc2cc(C)ccc21 -US08252935B2,7,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccn2)c1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCCN2)c1 -US20150191439A1,1,NC(=O)COc1ccc(C=O)cc1.NC12CC3CC(CC(C3)C1)C2>>NC(=O)COc1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1 -US06284764B1,3,C#C[Si](C)(C)C.CC(C)(C)[SiH2]OC(C)(C)C1CC(=O)CCO1>>CC(C)(C)[SiH2]OC(C)(C)C1CC(O)(C#C[Si](C)(C)C)CCO1 -US05656634,6,CCCCCCCCC(SCCCCCC)C(=O)Nc1c(NC(C)=O)ccc2ncccc12>>CCCCCCCCC(SCCCCCC)C(=O)Nc1c(N)ccc2ncccc12 -US08889741B2,7,COCCOCn1nccc1[C@H]1CCC(F)(F)C[C@@H]1OC(=O)c1ccccc1>>COCCOCn1nccc1[C@H]1CCC(F)(F)C[C@@H]1O -US05650428,1,CCOC(=O)Cc1ccc(NC(=O)C(COS(C)(=O)=O)NS(=O)(=O)c2ccc(I)cc2)cc1.Oc1ccccc1Cl>>CCOC(=O)Cc1ccc(NC(=O)C(COc2ccccc2Cl)NS(=O)(=O)c2ccc(I)cc2)cc1 -US20120232090A1,1,BrCCC1CO1.Cc1cccc(N2CCNCC2)c1C>>Cc1cccc(N2CCN(CCC3CO3)CC2)c1C -US20090312338A1,6,CC(C)(C)OC(=O)N(N)c1cnc2c(ccn2S(=O)(=O)c2ccc(C(C)(C)C)cc2)n1>>CC(C)(C)c1ccc(S(=O)(=O)n2ccc3nc(NN)cnc32)cc1 -US07705003B2,2,CN(C)C(=O)Cl.N[C@@H]1CC[C@@H](CCN2CCN(c3cccc4c3CCC4)CC2)CC1>>CN(C)C(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3cccc4c3CCC4)CC2)CC1 -US20100298287A1,9,Cc1cc(Cl)cc(Cl)c1N.S=C(Cl)Cl>>Cc1cc(Cl)cc(Cl)c1N=C=S -US08476302B2,3,C=CCCCCC(OC1CCCCC1)C(=O)OC.C=Cc1scnc1C>>COC(=O)C(CCCC/C=C/c1scnc1C)OC1CCCCC1 -US04119710,7,CC(C)(C)NCC(=O)c1cc(F)c(N)c(C#N)c1>>CC(C)(C)NCC(O)c1cc(F)c(N)c(C#N)c1 -US05223623,7,Nc1cccc(N2CCNC(C(=O)O)C2)c1>>Nc1cccc(N2CCNC(CO)C2)c1 -US07091222B2,1,CS(=O)(=O)OCC(F)(F)F.Cc1cc(C#Cc2c[nH]c(C)n2)ccn1>>Cc1cc(C#Cc2cn(CC(F)(F)F)c(C)n2)ccn1 -US06232318B1,1,CC(C)(C)OC(=O)NCCCBr.O=c1[nH]c(=O)n(Cc2ccccc2)cc1Br>>CC(C)(C)OC(=O)NCCCn1c(=O)c(Br)cn(Cc2ccccc2)c1=O -USRE045183E1,2,C[C@@H]1CC[C@@H](N(C(=O)Nc2ncc(Cl)s2)C2CCNCC2)CC1.O=C(Cl)N1CCCCC1>>C[C@@H]1CC[C@@H](N(C(=O)Nc2ncc(Cl)s2)C2CCN(C(=O)N3CCCCC3)CC2)CC1 -US03982019,2,CN.O=C=NC(F)(F)F>>CNC(=O)NC(F)(F)F -US20040176361A1,1,Cc1cccc2c(=O)[nH]c(Cl)cc12.OC[C@@H]1CNCCN1>>Cc1cccc2c(=O)[nH]c(N3CCN[C@H](CO)C3)cc12 -US04123537,7,CC(C)(C)c1cc(C#N)c(O)cn1>>CC(C)(C)c1cc(CN)c(O)cn1 -US20070254929A1,2,N[C@H](CO)C(C(F)(F)F)C(F)(F)F.O=S(=O)(Cl)c1ccsc1>>O=S(=O)(N[C@H](CO)C(C(F)(F)F)C(F)(F)F)c1ccsc1 -US20060241302A1,2,CN1CCNCC1.O=C(O)c1ccc(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(Cl)cc2)nc1>>CN1CCN(C(=O)c2ccc(C(c3cc(F)ccc3F)S(=O)(=O)c3ccc(Cl)cc3)nc2)CC1 -US20110230497A1,6,CCOC(=O)C[C@H]1CCN2C(=O)OC(C)(C)[C@H]2C1>>CC1(C)OC(=O)N2CC[C@H](CC(=O)O)C[C@@H]21 -US07935721B2,6,CCOC(=O)CN1C(=O)C2(COc3cc4c(cc32)CCO4)c2ccccc21>>O=C(O)CN1C(=O)C2(COc3cc4c(cc32)CCO4)c2ccccc21 -US08399491B2,1,C1CNC1.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(N2CCC2)nc1 -US20120172599A1,3,CN(C)C=O.COc1c(C=Cc2cccs2)cc2c3c1CCCN3CCC2>>COc1c(C=Cc2ccc(C=O)s2)cc2c3c1CCCN3CCC2 -US20140056849A1,1,CC(Cl)OC(=O)C1CCCC1.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2cn(C(C)OC(=O)C3CCCC3)c3ncc(-c4ccc(Cl)cc4)cc23)c1F -US05886008,1,Nc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1Nc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1 -US20150265612A1,2,Cc1ncc(N)cc1Br.O=C(O)C1(c2ccc3c(c2)OCO3)CC1>>Cc1ncc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)cc1Br -US08039500B2,4,CNc1c(N)cccc1N.O=C(O)Cc1c(Cl)cc(C(F)(F)F)cc1Cl>>Cn1c(Cc2c(Cl)cc(C(F)(F)F)cc2Cl)nc2cccc(N)c21 -US20090042917A1,6,CCC(C)c1c(Cl)nc(SC)nc1N(CC(F)(F)F)C(=O)OC(C)(C)C>>CCC(C)c1c(Cl)nc(SC)nc1NCC(F)(F)F -US20140051679A1,3,CC1(C)OB(c2cccc(CN3CCOCC3)c2)OC1(C)C.O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccsc1)N1CCCC1>>O=C(Nc1ccc2[nH]nc(-c3cccc(CN4CCOCC4)c3)c2c1)C(c1ccsc1)N1CCCC1 -US20120316147A1,2,CC(C)(N)c1nccs1.O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1>>CC(C)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)c1nccs1 -US20070197604A1,1,C1CCNCC1.Cc1oc(-c2ccc(Br)cc2)nc1CCOS(C)(=O)=O>>Cc1oc(-c2ccc(Br)cc2)nc1CCN1CCCCC1 -US07199239B2,7,CCCC(=O)Nc1cccc(-c2ccc(C)cc2)c1C>>CCCCNc1cccc(-c2ccc(C)cc2)c1C -US08327467B2,7,COc1ccccc1/C=C/c1ccc(C(=O)OC(C)(C)C)c(Nc2ccc(F)cc2)c1>>COc1ccccc1CCc1ccc(C(=O)OC(C)(C)C)c(Nc2ccc(F)cc2)c1 -US20040229858A1,6,COc1ccccc1NC(=O)Nc1ccc(CC(=O)OC(C)(C)C)cc1C>>COc1ccccc1NC(=O)Nc1ccc(CC(=O)O)cc1C -US20130225673A1,6,CCc1oc2ccccc2c1C(=O)c1ccc(OC)c(F)c1>>CCc1oc2ccccc2c1C(=O)c1ccc(O)c(F)c1 -US05206235,2,CC(C)=CC(=O)Cl.N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)C1=O>>CC(C)=CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)C1=O -US20110077234A1,6,CCOC(=O)CSc1cnc(NC(=O)N(CC2CCCC2)c2ccc(S(N)(=O)=O)cc2)s1>>NS(=O)(=O)c1ccc(N(CC2CCCC2)C(=O)Nc2ncc(SCC(=O)O)s2)cc1 -US07858640B2,6,COC(=O)C(C)(C)Oc1ccc(Cl)c2nc(OC(F)F)c(Cc3ccc(Cl)cc3)c(C)c12>>Cc1c(Cc2ccc(Cl)cc2)c(OC(F)F)nc2c(Cl)ccc(OC(C)(C)C(=O)O)c12 -US04596830,4,COc1cc(SC)sc1C(=O)O.Nc1cccnc1N>>COc1cc(SC)sc1-c1nc2ncccc2[nH]1 -US20120149721A1,2,CCC(=O)Cl.Cc1[nH]c2c(-c3cc(C(F)F)ccc3OCC3CC3)ncnc2c1C(=O)N[C@H]1CC[C@H](N)[C@@H](F)C1>>CCC(=O)N[C@H]1CC[C@H](NC(=O)c2c(C)[nH]c3c(-c4cc(C(F)F)ccc4OCC4CC4)ncnc23)C[C@@H]1F -US20120077812A1,1,CC(C)c1noc(N2CCC(CO)CC2)n1.Oc1ccc(Br)cc1>>CC(C)c1noc(N2CCC(COc3ccc(Br)cc3)CC2)n1 -US05859014,7,Fc1ccccc1-c1ncco1>>Fc1ccccc1C1=NCCO1 -US04602002,1,NC(CCC(O)CNC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O.O=C(O)C(=O)CCc1ccccc1>>O=C(NCC(O)CCC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)O)OCc1ccccc1 -US03971819,1,CN(C)CCCN.NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl>>CN(C)CCCNc1c([N+](=O)[O-])cc(C(=O)O)cc1S(N)(=O)=O -US06248894B1,1,CCNC(=O)c1c(Cl)cccc1[Si](C)(C)C.COCCl>>CCN(COC)C(=O)c1c(Cl)cccc1[Si](C)(C)C -US20080153828A1,1,CI.Cc1cc2cccc(C(C)C)c2[nH]1>>Cc1cc2cccc(C(C)C)c2n1C -US20090298899A1,2,N#Cc1cccc(N)c1.O=C(O)c1ccc(-c2ccccc2)o1>>N#Cc1cccc(NC(=O)c2ccc(-c3ccccc3)o2)c1 -US08691822B2,2,CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)O)c4c3OCC4)nc2N1C(C)C.CO[C@@H](CN)CN1CCN(C)CC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC[C@@H](CN4CCN(C)CC4)OC)c4c3OCC4)nc2N1C(C)C -US20100305099A1,1,CN(c1ncccc1CN)S(C)(=O)=O.Clc1ncc(Cl)c(Cl)n1>>CN(c1ncccc1CNc1nc(Cl)ncc1Cl)S(C)(=O)=O -US20040220403A1,6,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H](O)CN2[C@H](C(c2ccccc2)c2ccccc2)C1>>O[C@H]1C[C@H]2CNC[C@@H](C(c3ccccc3)c3ccccc3)N2C1 -US08283361B2,6,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(c2)c(=O)c(C(=O)OCC)cn3C[C@@H]2CCN(CCN3CCOCC3)C2)cn1>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(c2)c(=O)c(C(=O)O)cn3C[C@@H]2CCN(CCN3CCOCC3)C2)cn1 -US07601714B2,6,CC(C)(C)OC(=O)NCc1cccc(CNc2ncc([N+](=O)[O-])c(NCC3CCC(N4CCCC4)CC3)n2)c1>>NCc1cccc(CNc2ncc([N+](=O)[O-])c(NC[C@@H]3CC[C@@H](N4CCCC4)CC3)n2)c1 -US20110039852A1,3,CCN(Cc1cc(C(F)(F)F)ccc1B1OC(C)(C)C(C)(C)O1)C(=O)OCc1ccccc1.CCOC(=O)Cc1ccc(OCC2CC2)c(Br)c1>>CCOC(=O)Cc1ccc(OCC2CC2)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)OCc2ccccc2)c1 -US20150189884A1,2,CCCC(=O)Cl.NCc1ccc(C2=NOC(c3cc(Br)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1Cl>>CCCC(=O)NCc1ccc(C2=NOC(c3cc(Br)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1Cl -US20150210687A1,1,COC(=O)c1cc(F)c(-c2n[nH]c3cccc(F)c23)cc1OC.FC(F)(F)c1cccc(Br)c1CBr>>COC(=O)c1cc(F)c(-c2nn(Cc3c(Br)cccc3C(F)(F)F)c3cccc(F)c23)cc1OC -US20090082345A1,7,CCc1nc2c([N+](=O)[O-])cccc2o1>>CCc1nc2c(N)cccc2o1 -US20100016306A1,1,C1CCNCC1.O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>Clc1nc(N2CCOCC2)c2sc(CN3CCCCC3)cc2n1 -US20110009421A1,6,CCOC(=O)c1cccc(-c2ccnc(OCCc3ccc(OC)c(OC)c3)n2)c1>>COc1ccc(CCOc2nccc(-c3cccc(C(=O)O)c3)n2)cc1OC -US20080275032A1,2,CC(C)CCn1nc(-c2cccs2)c(O)c(C2=Nc3ccc(N)cc3S(=O)(=O)N2)c1=O.COC(=O)Cl>>COC(=O)Nc1ccc2c(c1)S(=O)(=O)NC(c1c(O)c(-c3cccs3)nn(CCC(C)C)c1=O)=N2 -US20110288291A1,6,Cc1nc2c(nc1N(C)C(C)C)OCCN(C(=O)OC(C)(C)C)C2>>Cc1nc2c(nc1N(C)C(C)C)OCCNC2 -US08791100B2,6,CC[C@@H](Nc1cnc(C)c(C(OC)OC)c1)c1ccc(Cl)c(C)c1>>CC[C@@H](Nc1cnc(C)c(C=O)c1)c1ccc(Cl)c(C)c1 -US20090105217A1,2,COC(=O)c1ccc(NC(=O)c2ccccc2F)cc1F.NN>>NNC(=O)c1ccc(NC(=O)c2ccccc2F)cc1F -US20090156582A1,6,CC(C)(C#N)CNC(=O)c1nn(C2CCCCO2)cc1NC(=O)c1ccccn1>>CC(C)(C#N)CNC(=O)c1n[nH]cc1NC(=O)c1ccccn1 -US20100331326A1,1,Cc1ccncc1N1CCNC1=O.Clc1cc(I)ccn1>>Cc1ccncc1N1CCN(c2ccnc(Cl)c2)C1=O -US20050131014A1,1,COC(=O)c1ccc(CBr)cc1.Oc1ccc(Oc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1>>COC(=O)c1ccc(COc2ccc(Oc3cccc(-c4c(Cc5ccccc5)cnc5c(C(F)(F)F)cccc45)c3)cc2)cc1 -US20090023725A1,3,Cc1ccc(C(=O)Nc2c(C)cnn2C)cc1B1OC(C)(C)C(C)(C)O1.Fc1ccc(-c2n[nH]c3cc(Br)ccc23)cc1>>Cc1ccc(C(=O)Nc2c(C)cnn2C)cc1-c1ccc2c(-c3ccc(F)cc3)n[nH]c2c1 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.O=C(Cl)COc1ccccc1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)COc4ccccc4)nc3cc21 -US20110009389A1,2,Cc1ncc2n1C(=O)N(C1CCNCC1)C2.O=C(O)CCS(=O)(=O)N1CCc2cc(Cl)ccc2C1>>Cc1ncc2n1C(=O)N(C1CCN(C(=O)CCS(=O)(=O)N3CCc4cc(Cl)ccc4C3)CC1)C2 -US20150183801A1,3,CC1(C)OB(c2cncc(C#N)c2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)F)c(F)c1)c1cnc(N2CC[C@H](CO)C2)c(Br)c1>>N#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)c(F)c3)cnc2N2CC[C@H](CO)C2)c1 -US20150148334A1,1,C1COCCN1.CN1CCC(c2ccc(Cl)cc2)c2cc(I)sc2C1=O>>CN1CCC(c2ccc(Cl)cc2)c2cc(N3CCOCC3)sc2C1=O -US07045528B2,6,COC[C@@H]1CCCN1C(=O)c1cc2nccc(Oc3ccc4c(C(=O)OC)c(C)sc4c3)c2s1>>COC[C@@H]1CCCN1C(=O)c1cc2nccc(Oc3ccc4c(C(=O)O)c(C)sc4c3)c2s1 -US06051570,7,Nc1cc(N2CCCCC2)ccc1[N+](=O)[O-]>>Nc1ccc(N2CCCCC2)cc1N -US20100256097A1,2,CC(C)N.O=C(O)CN(Cc1cccc(Br)n1)C(=O)OCc1ccccc1>>CC(C)NC(=O)CN(Cc1cccc(Br)n1)C(=O)OCc1ccccc1 -US04332948,1,CN(N)c1ccccc1.O=Cc1c2ccccc2cc2ccccc12>>CN(N=Cc1c2ccccc2cc2ccccc12)c1ccccc1 -US06355680B1,1,Cc1ccc(N)cc1C.O=C(O)Cc1ccccc1Br>>Cc1ccc(Nc2ccccc2CC(=O)O)cc1C -US20100004245A1,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.Oc1cc(F)ccc1Br>>CC(C)(C)OC(=O)N1CCC(Oc2cc(F)ccc2Br)CC1 -US07560475B2,7,FC(F)(F)c1ccncc1>>FC(F)(F)C1CCNCC1 -US04728646,1,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3c(NCc4ccc(Cl)c(Cl)c4)ncnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3c(NCc4ccc(Cl)c(Cl)c4)ncnc23)CC1 -US20080234383A1,2,CS(=O)(=O)Cl.N#Cc1ccc(N)c([N+](=O)[O-])c1>>CS(=O)(=O)Nc1ccc(C#N)cc1[N+](=O)[O-] -US08357705B2,1,CN(C)C1(c2ccccc2)CCC(=O)CC1.Cc1cnc([C@H](N)Cc2c[nH]c3ccccc23)o1>>Cc1cnc([C@@H](Cc2c[nH]c3ccccc23)NC2CCC(c3ccccc3)(N(C)C)CC2)o1 -US20060217380A1,3,CC1(C)OB(C2CC2)OC1(C)C.CN(C)CCCN(C)c1ccc(Br)cc1[N+](=O)[O-]>>CN(C)CCCN(C)c1ccc(C2CC2)cc1[N+](=O)[O-] -US20110086882A1,1,CCOC(=O)c1c(Br)n[nH]c1Br.COCCl>>CCOC(=O)c1c(Br)nn(COC)c1Br -US20030096829A1,1,Brc1ccc(Br)nc1.OCc1ccccc1>>Brc1ccc(OCc2ccccc2)nc1 -US20100331293A1,1,CC(C)c1c(-c2ccccn2)nc2cc(F)ccc2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>CC(C)c1c(-c2ccccn2)nc2cc(F)ccc2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1 -US06329366B1,1,CCS.O=[N+]([O-])c1ccc(Cl)cc1>>CCSc1ccc([N+](=O)[O-])cc1 -US07635715B2,6,CCC1(C)C(=O)C(C(=O)NCC(=O)OC(C)(C)C)=C(O)c2cc(Cl)ccc21>>CCC1(C)C(=O)C(C(=O)NCC(=O)O)=C(O)c2cc(Cl)ccc21 -US07514452B2,2,COc1ccc(C(=O)NNC(=O)c2occ(-c3ccccc3)c2-c2ccccc2)cc1N.CS(=O)(=O)Cl>>COc1ccc(C(=O)NNC(=O)c2occ(-c3ccccc3)c2-c2ccccc2)cc1NS(C)(=O)=O -US20150274696A1,9,Cc1cc2nc(Cl)ccn2n1.N>>Cc1cc2nc(N)ccn2n1 -US08952004B2,1,C1CCN(CCC2CCNCC2)CC1.O=C(NC1CC1)c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(NC1CC1)c1ccc(N2CCC(CCN3CCCCC3)CC2)c([N+](=O)[O-])c1 -US20080176857A1,1,CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(Cl)nc2s1.OCC(O)CS>>CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(SCC(O)CO)nc2s1 -US20100093774A1,7,Cc1nc2cccc([N+](=O)[O-])c2c(=O)n1[C@@]1(C)CCC(=O)NC1=O>>Cc1nc2cccc(N)c2c(=O)n1[C@@]1(C)CCC(=O)NC1=O -US20090069298A1,4,CCOC(=O)c1c(N)nn2c(-c3ccc(C(F)(F)F)cc3)c(-c3ccccc3Cl)cnc12.ClCCCCCl>>CCOC(=O)c1c(N2CCCC2)nn2c(-c3ccc(C(F)(F)F)cc3)c(-c3ccccc3Cl)cnc12 -US06627647B1,1,CC(C)(C)OC(=O)CN.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)OC(=O)CNc1ccc([N+](=O)[O-])cc1 -US06329389B1,6,CN(C)CC1CN(Cc2ccccc2)c2ccccc2N1C=O>>CN(C)CC1CNc2ccccc2N1C=O -US08552047B2,6,COC(=O)N[C@H](C(=O)OCc1ccccc1)C1C[C@@H](C)O[C@H](C)C1>>COC(=O)N[C@H](C(=O)O)C1C[C@@H](C)O[C@H](C)C1 -US06121271,6,COC(=O)c1csc(S(=O)(=O)Oc2ccc(-c3c4ccccc4c(Br)c4sc(C)c(C)c34)cc2C2CCCC2)c1OC>>COc1c(C(=O)O)csc1S(=O)(=O)Oc1ccc(-c2c3ccccc3c(Br)c3sc(C)c(C)c23)cc1C1CCCC1 -US08507476B2,2,CCOC(=O)N1CCn2c(nc(-c3ccncn3)cc2=O)C(N)C1.COc1cc(Cl)ccc1C(=O)O>>CCOC(=O)N1CCn2c(nc(-c3ccncn3)cc2=O)C(NC(=O)c2ccc(Cl)cc2OC)C1 -US20090181942A1,6,CCOC(=O)CC1CCN(C(=O)CC2OC(c3cccc4ccccc34)c3cc(Cl)ccc3-n3cccc32)CC1>>O=C(O)CC1CCN(C(=O)CC2OC(c3cccc4ccccc34)c3cc(Cl)ccc3-n3cccc32)CC1 -US08426420B2,6,CCOC(=O)c1cc(OCC(=O)OCc2ccccc2)n(-c2ccccc2)n1>>CCOC(=O)c1cc(OCC(=O)O)n(-c2ccccc2)n1 -US20130109685A1,1,BrCc1ccccc1.O=Cc1cc(F)ccc1O>>O=Cc1cc(F)ccc1OCc1ccccc1 -US20110275703A1,3,Cc1cc2c(cc1CCl)[C@]1(OC2)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1.O=Cc1ccc(B(O)O)cc1>>Cc1cc2c(cc1Cc1ccc(C=O)cc1)[C@]1(OC2)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US04789750,7,CC(=O)/C=C/C[C@H](C)CCC=C(C)C>>CC(C)=CCC[C@@H](C)C/C=C/C(C)O -US20030083333A1,2,CNC.COC(=O)Nc1cc(C(C)(C)C)cc(NC(=O)Nc2ccc(Oc3ccnc(C(=O)O)c3)c3ccccc23)c1OC>>COC(=O)Nc1cc(C(C)(C)C)cc(NC(=O)Nc2ccc(Oc3ccnc(C(=O)N(C)C)c3)c3ccccc23)c1OC -US08013008B2,1,CC[C@]1(O)CCN[C@H]1C(C)C.N#Cc1ccc(F)cc1Cl>>CC[C@]1(O)CCN(c2ccc(C#N)c(Cl)c2)[C@H]1C(C)C -US06034275,3,COc1cccc(C)c1F.O=C(Cl)c1ccc(Br)cc1>>COc1ccc(C(=O)c2ccc(Br)cc2)c(C)c1F -US20080269219A1,7,COC(=O)CCc1ccccc1OCCCc1oc(-n2ccnc2C)nc1-c1ccc(Cl)cc1>>Cc1nccn1-c1nc(-c2ccc(Cl)cc2)c(CCCOc2ccccc2CCCO)o1 -US05105012,7,O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>Nc1cc([N+](=O)[O-])ccc1F -US06096736,2,CC(C)N.CCCNc1ccc(C(=O)N2CCCC(CC(=O)O)c3ccccc32)c(Cl)c1>>CCCNc1ccc(C(=O)N2CCCC(CC(=O)NC(C)C)c3ccccc32)c(Cl)c1 -US07132436B2,2,Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Cl.Nc1nc(-c2cccnc2)cs1>>Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Nc1nc(-c2cccnc2)cs1 -USRE029628,6,CCOC(=O)c1ccc(N)c(CN(Cc2ccccc2)C(C)(C)C)c1>>CCOC(=O)c1ccc(N)c(CNC(C)(C)C)c1 -US07135467B2,2,COc1c(C(=O)O)nc(N2CCCCS2(=O)=O)n(C)c1=O.NCc1ccc(F)cc1>>COc1c(C(=O)NCc2ccc(F)cc2)nc(N2CCCCS2(=O)=O)n(C)c1=O -US20100292201A1,1,C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(=NO)CC[C@@H]12.O=C(O)COc1ccccc1>>C[C@]12CC[C@H](OC(=O)COc3ccccc3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(=NO)CC[C@@H]12 -US07157581B2,1,CCOC(=O)C(Cc1ccc(OCCBr)cc1)OCC.CCc1nc(-c2ccccc2)cc(=O)[nH]1>>CCOC(=O)C(Cc1ccc(OCCn2c(CC)nc(-c3ccccc3)cc2=O)cc1)OCC -US05688823,1,CC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1.CN(CC(O)CN)c1ccccc1>>CC(COc1ccc(CC2SC(=O)NC2=O)cc1)NCC(O)CN(C)c1ccccc1 -US20120295897A1,6,O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C12COc1ccc3nonc3c12>>O=C1Nc2ccccc2C12COc1ccc3nonc3c12 -US07495022B2,2,NCc1ccc(CO)cc1.O=C(O)c1ccc(N2CCCC2)cc1>>O=C(NCc1ccc(CO)cc1)c1ccc(N2CCCC2)cc1 -US08299267B2,9,Cc1c(CN=[N+]=[N-])cnn1C(C)(C)C>>Cc1c(CN)cnn1C(C)(C)C -US04933053,1,C=CCBr.c1ccc2c(c1)[nH]c1ccccc12>>C=CCn1c2ccccc2c2ccccc21 -US07151112B1,1,COC(=O)CO.O=C(Nc1ccc(F)cc1)c1ccc(Br)nc1>>COC(=O)COc1ccc(C(=O)Nc2ccc(F)cc2)cn1 -US08084620B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1c(N)cccc1Br>>Cc1c(N)cccc1B1OC(C)(C)C(C)(C)O1 -US20100144760A1,2,Cc1ccc(-c2ncc(C)o2)c(C(=O)O)n1.FC(F)(F)c1cnc(NC[C@@H]2C[C@H]3C[C@H]3CN2)nc1>>Cc1ccc(-c2ncc(C)o2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CNc2ncc(C(F)(F)F)cn2)n1 -US20130274260A1,1,CCOC(=O)c1cccc(O)c1.Cc1cccc(B(O)O)c1>>CCOC(=O)c1cccc(Oc2cccc(C)c2)c1 -US20150252044A1,3,NC(=O)c1ccc2cncc(Br)c2n1.OB(O)c1cc(F)c(F)c(F)c1>>NC(=O)c1ccc2cncc(-c3cc(F)c(F)c(F)c3)c2n1 -US06476021B1,1,ClCc1cccnc1.O=c1c(Cc2cccnc2)cn2c3c(cc(O)cc13)Sc1cc(Br)ccc1-2>>O=c1c(Cc2cccnc2)cn2c3c(cc(OCc4cccnc4)cc13)Sc1cc(Br)ccc1-2 -US20100063038A1,2,CC1(C)OB(c2cc(F)c(N)c(F)c2)OC1(C)C.O=C=Nc1cc(C(F)(F)F)ccc1F>>CC1(C)OB(c2cc(F)c(NC(=O)Nc3cc(C(F)(F)F)ccc3F)c(F)c2)OC1(C)C -US20080255083A1,6,O=c1cc(OCc2ccc(F)cc2)cnn1C1CCCCO1>>O=c1cc(OCc2ccc(F)cc2)cn[nH]1 -US20070213348A1,3,C=CC(=O)OC(C)(C)C.Oc1ccc(C(=C2CCSCC2)c2ccc(Br)cc2)cc1>>CC(C)(C)OC(=O)/C=C/c1ccc(C(=C2CCSCC2)c2ccc(O)cc2)cc1 -US08859584B2,2,CC(=O)Cl.Oc1cccc(F)c1F>>CC(=O)Oc1cccc(F)c1F -US05962473,2,CN1CCC(c2c[nH]c3ccc(N)cc23)CC1.O=C(O)c1ccc(I)cc1>>CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccc(I)cc4)cc23)CC1 -US20050043368A1,9,C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@@H](C=O)NC(=O)OC(C)(C)C -US20100292210A1,1,COc1cc(N)ccc1-n1cnc(C)n1.Clc1ccc2c(n1)O[C@H](c1ccccc1)CN(C1CC1)C2>>COc1cc(Nc2ccc3c(n2)O[C@H](c2ccccc2)CN(C2CC2)C3)ccc1-n1cnc(C)n1 -US20110237791A1,3,C#CCO.COc1nc(Br)ccc1Cl>>COc1nc(C#CCO)ccc1Cl -US20150004181A1,7,CN1CCC(OC(c2cccc(C#CCCN)c2)c2nc3ccccc3[nH]2)CC1>>CN1CCC(OC(c2cccc(CCCCN)c2)c2nc3ccccc3[nH]2)CC1 -US20150164876A1,1,CNCCN1CCN(C(=O)OC(C)(C)C)CC1.O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(-c2cc(N3CCCCC3)ccc2NC(=O)c2cccc(CCl)c2)c1>>CN(CCN1CCN(C(=O)OC(C)(C)C)CC1)Cc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1 -US20080306120A1,3,C[Si](C)(C)c1cc2c(Br)ccnc2n1S(=O)(=O)c1ccccc1.Cn1cc(B2OC(C)(C)C(C)(C)O2)c(-c2ccc([N+](=O)[O-])cc2)n1>>Cn1cc(-c2ccnc3c2cc([Si](C)(C)C)n3S(=O)(=O)c2ccccc2)c(-c2ccc([N+](=O)[O-])cc2)n1 -US20040204427A1,6,CCc1ccc(N2Cc3cnc(Nc4ccc(F)cc4)nc3N([C@H]3CC[C@H](O[Si](C)(C)C(C)(C)C)C3)C2=O)cc1>>CCc1ccc(N2Cc3cnc(Nc4ccc(F)cc4)nc3N([C@H]3CC[C@H](O)C3)C2=O)cc1 -US20070249670A1,2,Cc1cccc(C)c1N=C=O.Nc1cc2ccccc2cc1C(=O)N(CC(=O)OCc1ccccc1)C1CCCC1>>Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N(CC(=O)OCc1ccccc1)C1CCCC1 -US20100113782A1,6,CCOC(=O)c1ccc(N2CCN(c3ccc(C(=O)Nc4cccc(C(C)(C)C)c4)cc3)CC2)cc1>>CC(C)(C)c1cccc(NC(=O)c2ccc(N3CCN(c4ccc(C(=O)O)cc4)CC3)cc2)c1 -US07572794B2,1,Cn1cc2ccc(NC(=O)c3ccccc3NCc3ccnc(Br)c3)cc2n1.NC(=O)N1CCSCC1>>Cn1cc2ccc(NC(=O)c3ccccc3NCc3ccnc(NC(=O)N4CCSCC4)c3)cc2n1 -US04798837,1,CC(=O)Nc1cc(Cl)c(O)cc1Cl.FC(F)=C(F)C(F)(F)F>>CC(=O)Nc1cc(Cl)c(OC(F)(F)C(F)C(F)(F)F)cc1Cl -US04017522,2,CCCCCCCC/C=C\CCCCCCCC(=O)Cl.Cc1ccc(C(=O)N(C)CCO)cc1>>CCCCCCCC/C=C\CCCCCCCC(=O)OCCN(C)C(=O)c1ccc(C)cc1 -US06448243B1,1,CCN1CCC(=O)CC1.Fc1ccc(CC2CNc3ccccc32)cc1>>CCN1CCC(N2CC(Cc3ccc(F)cc3)c3ccccc32)CC1 -US20150031685A1,1,N#CCBr.O=Cc1cccc(O)c1>>N#CCOc1cccc(C=O)c1 -US20100113539A1,2,CC(C)(C)OC(=O)NCCOc1cccc(N)c1.O=S(=O)(Cl)C1CCCCC1>>CC(C)(C)OC(=O)NCCOc1cccc(NS(=O)(=O)C2CCCCC2)c1 -US20140073634A1,1,Cc1ccc(CBr)cc1.O=c1ccc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)c[nH]1>>Cc1ccc(Cn2cc(-c3nc(-c4ccc(OC(F)(F)F)cc4)no3)ccc2=O)cc1 -US08211513B2,3,CCCCC1CCC(c2ccc(B3OC(C)(C)C(C)(C)O3)c(F)c2)OC1.Fc1cc(OC(F)(F)c2c(F)cc(Br)cc2F)cc(F)c1C(F)(F)F>>CCCCC1CCC(c2ccc(-c3cc(F)c(C(F)(F)Oc4cc(F)c(C(F)(F)F)c(F)c4)c(F)c3)c(F)c2)OC1 -US07468365B2,2,CNCC(OC)OC.O=C(Cl)Cc1ccccc1>>COC(CN(C)C(=O)Cc1ccccc1)OC -US05334716,3,CC(=O)Oc1ccc(C(=O)Cl)cc1.CCOC(=O)CCCc1ccc2ccccn12>>CCOC(=O)CCCc1cc(C(=O)c2ccc(OC(C)=O)cc2)c2ccccn12 -US05011927,1,Fc1cc(F)nc(F)n1.NCc1ccccc1>>Fc1cc(F)nc(NCc2ccccc2)n1 -US20110212968A1,1,Cc1ccc2nc(CCN)[nH]c2c1.O=CC1CC1>>Cc1ccc2nc(CCNCC3CC3)[nH]c2c1 -US05269964,1,CCCCCCCCc1ccc(-c2ncc(-c3ccc(O)cc3)s2)cc1.CCCCCCI>>CCCCCCCCc1ccc(-c2ncc(-c3ccc(OCCCCCC)cc3)s2)cc1 -US20060217564A1,6,COc1ccc([C@@H]2COc3c(ccc(OC(C)=O)c3C)[C@H]2O)cc1>>COc1ccc([C@@H]2COc3c(ccc(O)c3C)[C@H]2O)cc1 -US20100166706A1,1,CC(C)C[C@@H](COS(C)(=O)=O)NC(=O)OC(C)(C)C.[N-]=[N+]=[N-]>>CC(C)C[C@@H](CN=[N+]=[N-])NC(=O)OC(C)(C)C -US20140213586A1,1,COc1cccc(N)c1.O=Cc1ccc(-c2cncnc2)cc1>>COc1cccc(N=Cc2ccc(-c3cncnc3)cc2)c1 -US20110212053A1,3,Brc1ccc(Oc2ccccc2)nc1.CC(C)(C#N)c1ccc(Cc2c([N+](=O)[O-])cnc3ccc(B4OC(C)(C)C(C)(C)O4)cc23)cc1>>CC(C)(C#N)c1ccc(Cc2c([N+](=O)[O-])cnc3ccc(-c4ccc(Oc5ccccc5)nc4)cc23)cc1 -US07329678B2,3,N#Cc1cccc(B(O)O)c1.Nc1ncc(Br)cc1C=O>>N#Cc1cccc(-c2cnc(N)c(C=O)c2)c1 -US20140288045A1,2,CC(C)(C)OC(=O)N1CCNCC1.COc1cc(Cl)c(I)cc1NCC(=O)O>>COc1cc(Cl)c(I)cc1NCC(=O)N1CCN(C(=O)OC(C)(C)C)CC1 -US20020052376A1,6,COC(=O)c1cc(C(OCCc2cncn2C)c2nccs2)ccc1CCc1ccc(F)cc1>>Cn1cncc1CCOC(c1ccc(CCc2ccc(F)cc2)c(C(=O)O)c1)c1nccs1 -US20150252011A1,6,COC(=O)c1ncc(Cl)nc1C>>Cc1nc(Cl)cnc1C(=O)O -US09035059B2,1,COc1ccc(C=O)c(OC)c1.Nc1ccc(F)cc1>>COc1ccc(CNc2ccc(F)cc2)c(OC)c1 -US04950677,1,COc1ccnc(CCl)c1C.Fc1cc2nc(S)[nH]c2cc1F>>COc1ccnc(CSc2nc3cc(F)c(F)cc3[nH]2)c1C -US06531491B1,1,C[Si](C)(C)CCOCn1nc(C=Cc2ccccc2)c2ccc(N)cc21.O=[N+]([O-])c1cccc(I)c1>>C[Si](C)(C)CCOCn1nc(C=Cc2ccccc2)c2ccc(Nc3cccc([N+](=O)[O-])c3)cc21 -US07368578B2,3,CCOC(=O)CP(=O)(OCC)OCC.COc1cc(COc2nn(-c3ccc(C(F)(F)F)cc3)cc2C=O)ccc1OCc1nc(-c2ccccc2)oc1C>>CCOC(=O)/C=C/c1cn(-c2ccc(C(F)(F)F)cc2)nc1OCc1ccc(OCc2nc(-c3ccccc3)oc2C)c(OC)c1 -US20030078278A1,2,CN.O=C(O)C1Cc2ccccc2N1C(=O)CCN1CCC2(CCc3ccccc32)CC1>>CNC(=O)C1Cc2ccccc2N1C(=O)CCN1CCC2(CCc3ccccc32)CC1 -US20080090860A1,3,CC(=O)c1cc2c(I)cccc2s1.CC(C)c1cc(B(O)O)c(OCC(F)(F)F)c(C(C)C)c1>>CC(=O)c1cc2c(-c3cc(C(C)C)cc(C(C)C)c3OCC(F)(F)F)cccc2s1 -US20140113917A1,10,Cc1ccc(Br)cc1C(F)(F)F.O=C1CCC(=O)N1Br>>FC(F)(F)c1cc(Br)ccc1CBr -US08198456B2,6,CCNc1nn(C(=O)OC(C)(C)C)c2ccc(C3C(C#N)=C(C)NC(C)=C3C#N)cc12>>CCNc1n[nH]c2ccc(C3C(C#N)=C(C)NC(C)=C3C#N)cc12 -US20070265278A1,2,NC1CCCCC1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=S(=O)(NC1CCCCC1)c1ccc(Br)cc1 -US07557213B2,1,Cc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1C.Fc1cccc(CBr)n1>>Cc1ccc(C(=O)c2cn(Cc3cccc(F)n3)c3ccccc3c2=O)cc1C -US07816387B2,2,C[C@@H](NC(=O)c1cc(C(=O)O)cc(N(C)S(C)(=O)=O)c1)c1ccccc1.N[C@@H](Cc1ccccc1)[C@@H](O)C(=O)Nc1ncc[nH]1>>C[C@@H](NC(=O)c1cc(C(=O)N[C@@H](Cc2ccccc2)[C@@H](O)C(=O)Nc2ncc[nH]2)cc(N(C)S(C)(=O)=O)c1)c1ccccc1 -US20090311217A1,1,CN1CCN(CCCl)CC1.COc1ccc2[nH]c(-c3c(C)noc3C)c(C=O)c2c1>>COc1ccc2c(c1)c(C=O)c(-c1c(C)noc1C)n2CCN1CCN(C)CC1 -US20050171163A1,1,O=C(CBr)CS(=O)(=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1.SCc1ccccc1>>O=C(CSCc1ccccc1)CS(=O)(=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 -US07563815B2,2,Cn1c(N(Cc2ccc(C(=O)O)cc2)C2CCC(C(C)(C)C)CC2)nc2ccccc21.NCc1nnn[nH]1>>Cn1c(N(Cc2ccc(C(=O)NCc3nnn[nH]3)cc2)C2CCC(C(C)(C)C)CC2)nc2ccccc21 -US07005440B1,1,Cc1cccc(COc2cccc(O)c2)c1OCC#N.OCCc1ccccn1>>Cc1cccc(COc2cccc(OCCc3ccccn3)c2)c1OCC#N -US20150210688A1,7,CCOC(=O)c1nn(Cc2ccccc2)cc1C>>Cc1cn(Cc2ccccc2)nc1CO -US07544685B2,3,CC(C)(C)OC(=O)n1ccc2cc(Br)ccc21.OB(O)c1ccncc1>>CC(C)(C)OC(=O)n1ccc2cc(-c3ccncc3)ccc21 -US04556677,1,CCC(=C(c1ccccc1)c1ccc(O)cc1)C1CCCC1.OCC(O)CCl>>CCC(=C(c1ccccc1)c1ccc(OCC(O)CO)cc1)C1CCCC1 -US20100041657A1,8,CSc1cc(C(C)(C)C)c(O)c(C(=O)Nc2ccc(S(=O)(=O)C(F)(F)F)cc2Cl)c1C.O=C(OO)c1cccc(Cl)c1>>Cc1c(S(C)=O)cc(C(C)(C)C)c(O)c1C(=O)Nc1ccc(S(=O)(=O)C(F)(F)F)cc1Cl -US20120129840A1,1,CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1.CN1CCNCC1>>CCCC(C(=O)OC)c1c(C)nc(N2CCN(C)CC2)nc1-c1ccc(C)cc1 -US20090221555A1,1,CCNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.COc1cc2c(cc1N)CCN(CC(C)(F)F)CC2>>CCNC(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(CC(C)(F)F)CC3)ncc1Cl -US20120244120A1,6,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCC(C)c3ccnc(NC(=O)OC(C)(C)C)c3)c3ccccc23)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCC(C)c3ccnc(N)c3)c3ccccc23)cc1 -US20130022629A1,2,COCc1nnc(N)s1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>COCc1nnc(NS(=O)(=O)c2ccc([N+](=O)[O-])cc2)s1 -US08822470B2,1,CN1CC(=O)Nc2cc(CO)cnc21.Clc1ccc(C2=CCNCC2)cc1>>CN1CC(=O)Nc2cc(CN3CC=C(c4ccc(Cl)cc4)CC3)cnc21 -US07528150B2,7,Cc1cc2c([N+](=O)[O-])cccc2cn1>>Cc1cc2c(N)cccc2cn1 -US04698337,9,O=CNc1nc(C(=NOCCBr)C(=O)O)cs1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCON=C(C(=O)O)c1csc(NC=O)n1 -US04772600,2,CCCN.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>CCCNC(=O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21 -US20140148443A1,2,CCOc1cc(Cl)c(S(C)(=O)=O)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)Cl.CN(C)CCCN(C)C1CCNC1>>CCOc1cc(Cl)c(S(C)(=O)=O)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(N(C)CCCN(C)C)C1 -US20030207889A1,10,Br.C=C(CCCN1C(=O)c2ccccc2C1=O)C(=O)O>>O=C(O)C(CBr)CCCN1C(=O)c2ccccc2C1=O -US07399781B2,2,COC(=O)c1cc(S(C)(=O)=O)c(N)cc1C.Cc1c(S(=O)(=O)Cl)sc2ccc(Cl)cc12>>COC(=O)c1cc(S(C)(=O)=O)c(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1C -US20090286778A1,2,O=C(Nc1ccc2cc1CCc1cccc(c1)Nc1ncc(Cl)c(n1)N2)[C@@H]1CCCN1.O=C=Nc1ccccc1>>O=C(Nc1ccc2cc1CCc1cccc(c1)Nc1ncc(Cl)c(n1)N2)[C@@H]1CCCN1C(=O)Nc1ccccc1 -US20100311714A1,1,CN.Fc1cncc(Br)c1>>CNc1cncc(Br)c1 -US04088491,1,CCCCCCCCCCCCCCCCS(=O)[O-].O=C1Cc2ccccc2C1Br>>CCCCCCCCCCCCCCCCS(=O)(=O)C1C(=O)Cc2ccccc21 -US06432950B1,1,O=[N+]([O-])c1cccc(CNc2nc(Cl)nc3sc([N+](=O)[O-])cc23)c1.c1c[nH]cn1>>O=[N+]([O-])c1cccc(CNc2nc(-n3ccnc3)nc3sc([N+](=O)[O-])cc23)c1 -US20070207991A1,7,CC(=O)N(C)C1CCN(c2ccc([N+](=O)[O-])cc2)C1>>CC(=O)N(C)C1CCN(c2ccc(N)cc2)C1 -US20110212956A1,2,CC(=O)OC(C)=O.COc1ccccc1CCN>>COc1ccccc1CCNC(C)=O -US20150225335A1,1,CCOC1CNC1.CNC(=O)[C@@](C)(C(=O)NOC1CCCCO1)N(C)C(=O)c1ccc(C#Cc2ccc(C=O)cc2)cc1>>CCOC1CN(Cc2ccc(C#Cc3ccc(C(=O)N(C)[C@@](C)(C(=O)NC)C(=O)NOC4CCCCO4)cc3)cc2)C1 -US20040214888A1,9,COC(=O)c1cccc(-c2ccc(Cl)c(CNC(=O)OC(C)(C)C)c2)c1>>COC(=O)c1cccc(-c2cccc(CNC(=O)OC(C)(C)C)c2)c1 -US05709867,6,CC1(C)CCC(C)(C)c2cc(C(N)C(=O)Nc3ccc(C(=O)OCc4ccccc4)cc3)ccc21>>CC1(C)CCC(C)(C)c2cc(C(N)C(=O)Nc3ccc(C(=O)O)cc3)ccc21 -US20100130538A1,6,Cn1cc2c([C@@H]3C[C@H]3CNC(=O)OC(C)(C)C)cccc2n1>>Cn1cc2c([C@@H]3C[C@H]3CN)cccc2n1 -US08063071B2,3,CC(C)CCNCc1ccc(B(O)O)s1.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc(CNCCC(C)C)s4)cc23)CC1 -US07507841B2,3,CC(=O)Nc1cccc(B(O)O)c1.Cc1c(Br)c2c(c(C)c1NC(=O)CC(C)(C)C)C(c1ccc(C(C)C)cc1)CO2>>CC(=O)Nc1cccc(-c2c(C)c(NC(=O)CC(C)(C)C)c(C)c3c2OCC3c2ccc(C(C)C)cc2)c1 -US08586550B2,2,NCC(=O)Cc1cc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)ccc1Cl.O=C(O)c1ccccc1>>O=C(CNC(=O)c1ccccc1)Cc1cc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)ccc1Cl -US05814653,2,CN(C)C1CCc2[nH]c3ccc(N)cc3c2C1.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)Nc2ccc3[nH]c4c(c3c2)CC(N(C)C)CC4)c1 -US20110245303A1,6,CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2COC(=O)N(CC)Cc2ccccc2)c1>>CCN(Cc1ccccc1)C(=O)OCc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC -US20090198063A1,6,O=c1ccc2ccncc2n1CC1OCCO1>>O=CCn1c(=O)ccc2ccncc21 -US20120022056A1,3,Brc1cccc2ncccc12.C=CC[Sn](CCCC)(CCCC)CCCC>>C=CCc1cccc2ncccc12 -US07700657B2,9,CC/C(=C\C=C(Br)Br)c1cccc(CCc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)c1>>C#C/C=C(\CC)c1cccc(CCc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)c1 -US07935715B2,6,CCOC(=O)C(C)(C)S(=O)(=O)c1cccnc1>>CC(C)(C(=O)O)S(=O)(=O)c1cccnc1 -US06660742B2,2,Nc1cc(O)ccc1CCCl.O=C(O)c1cc2cc([N+](=O)[O-])ccc2[nH]1>>O=C(Nc1cc(O)ccc1CCCl)c1cc2cc([N+](=O)[O-])ccc2[nH]1 -US20140194431A1,2,CC(C)(C)[Si](C)(C)OCCNCc1ccccc1.O=C(O)c1nc(CC2(c3ccc(Cl)cc3)CCCC2)nc(O)c1OCc1ccccc1>>CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)C(=O)c1nc(CC2(c3ccc(Cl)cc3)CCCC2)nc(O)c1OCc1ccccc1 -US08748426B2,2,COC(=O)C1(N2Cc3ccc(-c4ccc(N)cc4)cc3C2=O)CCC1.Cc1ccc(C(=O)Cl)cc1>>COC(=O)C1(N2Cc3ccc(-c4ccc(NC(=O)c5ccc(C)cc5)cc4)cc3C2=O)CCC1 -US20100048610A1,2,CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1ccc([N+](=O)[O-])c(CO)c1.O=C=Nc1ccccc1>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1ccc([N+](=O)[O-])c(COC(=O)Nc2ccccc2)c1 -US07576098B2,1,C1COCCN1.CCc1ccc(F)c(Br)c1>>CCc1ccc(F)c(N2CCOCC2)c1 -US08969565B2,6,CC(C)(C)OC(=O)N1CCN(c2ccc3ncc(Br)n3n2)CC1>>Brc1cnc2ccc(N3CCNCC3)nn12 -US20040209859A1,6,CCOC(=O)C1C2CC3CCCC3C21>>O=C(O)C1C2CC3CCCC3C21 -US05624942,1,Clc1cccc(OCc2ccsc2)n1.Oc1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(Oc2cccc(OCc3ccsc3)n2)c1 -US06156767,7,OC#CCCc1ccnc2cc(Cl)ccc12>>OCCCCc1ccnc2cc(Cl)ccc12 -US20030176454A1,1,Cc1ncc(-c2cccc(Nc3nnc(Cl)c4ccccc34)c2)n1C.Oc1ccccc1>>Cc1ncc(-c2cccc(Nc3nnc(Oc4ccccc4)c4ccccc34)c2)n1C -US20050227976A1,1,COC(=O)c1ccc(OCCN(C(=O)C=CCBr)c2cc3ccccc3o2)cc1.OCCN1CCCC1>>COC(=O)c1ccc(OCCN(C(=O)C=CCOCCN2CCCC2)c2cc3ccccc3o2)cc1 -US20090163488A1,2,CCn1cc(C)c(C(=O)O)n1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>CCn1cc(C)c(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)n1 -US20140107109A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@]1(c2cc(Br)ccc2F)CS(=O)(=O)C2(CC2)C(N)=N1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(Br)ccc2F)CS(=O)(=O)C12CC2 -US20120115906A1,3,COC(=O)c1sc(-c2ccc(Cl)cc2Cl)c(Br)c1OC.OB(O)c1ccc(Cl)cc1>>COC(=O)c1sc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1OC -US20140094462A1,2,C=CCC(F)(F)C(=O)O.N[C@@H](CO)c1ccccc1>>C=CCC(F)(F)C(=O)N[C@@H](CO)c1ccccc1 -US20060141043A1,2,CCOC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)s1.CCOCCN>>CCOCCNC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)s1 -US20150191439A1,1,NC12CC3CC(CC(C3)C1)C2.O=Cc1ccc(-c2ccn[nH]2)o1>>c1cc(-c2ccc(CNC34CC5CC(CC(C5)C3)C4)o2)[nH]n1 -US06150397,1,CI.CS(=O)(=O)c1ccc2c(C(=O)c3ccc(F)cc3)c(O)ccc2c1>>COc1ccc2cc(S(C)(=O)=O)ccc2c1C(=O)c1ccc(F)cc1 -US20130310333A1,2,CN(CCCN)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21.O=C=Nc1cccc(Cl)c1>>CN(CCCNC(=O)Nc1cccc(Cl)c1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21 -US20040209886A1,7,CCOC(=O)c1ccc2c(Nc3ccc(Oc4ccccc4)cc3)c(C#N)cnn12>>N#Cc1cnn2c(CO)ccc2c1Nc1ccc(Oc2ccccc2)cc1 -US20150191468A1,2,CS(=O)(=O)Cl.Cc1ccc(S(=O)(=O)n2cc(-c3cc(N[C@H](CO)C(C)(C)C)c(F)cn3)c3cc(F)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cc(N[C@H](COS(C)(=O)=O)C(C)(C)C)c(F)cn3)c3cc(F)cnc32)cc1 -US07923561B2,1,NCC1CC1.O=S(=O)(Nc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12)c1ccc(F)cc1>>O=S(=O)(Nc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12)c1ccc(NCC2CC2)cc1 -US04203987,1,ClCc1ccncc1.O=C1Nc2cc(F)ccc2N2CCNCC12>>O=C1Nc2cc(F)ccc2N2CCN(Cc3ccncc3)CC12 -US20070123512A1,2,C=C(C)C(=O)Cl.Cc1cc(N)ccc1[N+](=O)[O-]>>C=C(C)C(=O)Nc1ccc([N+](=O)[O-])c(C)c1 -US08003659B2,6,C#CC1(S(=O)(=O)NC(=O)OC(C)(C)C)CC1>>C#CC1(S(N)(=O)=O)CC1 -US20070161627A1,6,COc1ccc2nccc(CCC3(O)CCN(C(=O)OC(C)(C)C)CC3)c2n1>>COc1ccc2nccc(CCC3(O)CCNCC3)c2n1 -US07655679B2,10,Cc1ccc(C#N)c(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>N#Cc1ccc(CBr)cc1C(F)(F)F -US06156903,1,CNC1CNC1.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(Cl)cc1F>>CNC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4nc(N)c(F)cc4Cl)c3c2Cl)C1 -US20100081678A1,3,N#Cc1ccc(Cn2cc(C=O)c3ccccc32)cc1.O=C1CC(=O)NC(=O)N1>>N#Cc1ccc(Cn2cc(C=C3C(=O)NC(=O)NC3=O)c3ccccc32)cc1 -US20070249637A1,6,COC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](Oc3nc(-c4cc(C)nn4C)nc4ccsc34)C[C@H]1C(=O)N2>>Cc1cc(-c2nc(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)O)C[C@H]5C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N4C3)c3sccc3n2)n(C)n1 -US07351719B2,7,CCN(CC)CCOc1ccc([N+](=O)[O-])c(Cl)c1>>CCN(CC)CCOc1ccc(N)c(Cl)c1 -US20060111371A1,7,CC1CN=C(c2ccc([N+](=O)[O-])cc2)N(C(=O)OC(C)(C)C)C1>>CC1CN=C(c2ccc(N)cc2)N(C(=O)OC(C)(C)C)C1 -US06664271B1,2,CCOC(=O)C1CNCCC1C.O=C(Cl)Cc1cccs1>>CCOC(=O)C1CN(C(=O)Cc2cccs2)CCC1C -US05312820,2,CCCCCNCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.O=C(Cl)N1CCCc2ccccc21>>CCCCCN(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)C(=O)N1CCCc2ccccc21 -US06531494B1,3,C#C[Si](C)(C)C.CC(C)(CC(=O)O)Cc1ccc(OCCCNc2ccccn2)c(Br)c1>>C#Cc1cc(CC(C)(C)CC(=O)O)ccc1OCCCNc1ccccn1 -US20130165464A1,1,CC(=O)Nc1cc(Br)c(C)cn1.CCOC(=O)c1c[nH]cc1-c1ccccc1Cl>>CCOC(=O)c1cn(-c2cc(NC(C)=O)ncc2C)cc1-c1ccccc1Cl -US05610303,3,O=C1CCc2cc(Nc3ncnc4c3CCC4)ccc21.O=CC1CCN(Cc2ccccc2)CC1>>O=C1C(=CC2CCN(Cc3ccccc3)CC2)Cc2cc(Nc3ncnc4c3CCC4)ccc21 -US04617388,2,CN(C)S(=O)(=O)Oc1ccccc1S(=O)(=O)N=C=O.Cc1cc(C)nc(N)n1>>Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OS(=O)(=O)N(C)C)n1 -US20130190289A1,2,COC(=O)c1sc(C#CC2(C)CC2)cc1NCC(=O)N1CCOCC1.C[C@@H]1CC[C@@H](C(=O)Cl)CC1>>COC(=O)c1sc(C#CC2(C)CC2)cc1N(CC(=O)N1CCOCC1)C(=O)[C@@H]1CC[C@@H](C)CC1 -US09073891B2,2,COC(=O)c1ncsc1N.O=C(O)Cc1cccc2cnccc12>>COC(=O)c1ncsc1NC(=O)Cc1cccc2cnccc12 -US20100016396A1,6,COC(=O)[C@H](C)Oc1cc(Oc2c(C=C(C)C)c(C)nn2C)c(Cl)cc1Cl>>CC(C)=Cc1c(C)nn(C)c1Oc1cc(O[C@@H](C)C(=O)O)c(Cl)cc1Cl -US06509361B1,1,COC(=O)c1ccnc(Cl)c1.C[O-]>>COC(=O)c1ccnc(OC)c1 -US04698231,7,CC1(C)CCC(C)(C)C1OCC(C)(C)[N+](=O)[O-]>>CC(C)(N)COC1C(C)(C)CCC1(C)C -US07414134B2,7,N[C@H](C(=O)O)c1ccc(F)cc1>>N[C@H](CO)c1ccc(F)cc1 -US20150051199A1,6,CC[C@@H](NC(=O)OC(C)(C)C)c1ccc(Cl)c(C(=O)c2ccc(C(=O)O)nc2)c1F>>CC[C@@H](N)c1ccc(Cl)c(C(=O)c2ccc(C(=O)O)nc2)c1F -US08026247B2,6,O=C(Nc1ccc(F)c(C(F)(F)F)c1)N1COc2cc(OCc3ccccc3)ccc21>>O=C(Nc1ccc(F)c(C(F)(F)F)c1)N1COc2cc(O)ccc21 -US20140088076A1,8,Cc1ncc(Br)c(C)c1Cl.O=C(OO)c1cccc(Cl)c1>>Cc1c(Br)c[n+]([O-])c(C)c1Cl -US05929097,3,COC(=O)c1cc(Br)cc(C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1.O=Cc1ccccc1B(O)O>>COC(=O)c1cc(-c2ccccc2C=O)cc(C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.O=C=Nc1ccc2ccccc2c1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)Nc3ccc4ccccc4c3)CC2)nc1C(F)(F)F -US20110105514A1,6,CC(C)(C)OC(=O)NCCn1cc(I)nc1CC1CC1>>NCCn1cc(I)nc1CC1CC1 -US20110021479A1,2,CCC(=O)Cl.CCOc1ccc2c(c1-c1ncnc3c(C(=O)N[C@@H]4CCNC4)c[nH]c13)OCO2>>CCOc1ccc2c(c1-c1ncnc3c(C(=O)N[C@@H]4CCN(C(=O)CC)C4)c[nH]c13)OCO2 -US20090221555A1,1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.COCCNC1CCCc2c(ccc(N)c2OC)C1>>COCCNC1CCCc2c(ccc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)c2OC)C1 -US08772280B2,3,CC(=O)c1ccc[nH]1.O=C(Cl)C(Cl)(Cl)Cl>>CC(=O)c1cc(C(=O)C(Cl)(Cl)Cl)c[nH]1 -US07923573B2,7,C=C(C)c1cc(CC#N)ccc1OC>>COc1ccc(CC#N)cc1C(C)C -US20090281097A1,2,CCN(C(=O)C1CCCN(C2CCNCC2)C1)C(C)C.COc1cccc2c(C(=O)O)c(N)sc12>>CCN(C(=O)C1CCCN(C2CCN(C(=O)c3c(N)sc4c(OC)cccc34)CC2)C1)C(C)C -US20070155743A1,8,COCCCOc1ccccc1C(=O)NC[C@@H](C[C@@H](CO)NC(=O)OC(C)(C)C)C(C)C>>COCCCOc1ccccc1C(=O)NC[C@@H](C[C@@H](C=O)NC(=O)OC(C)(C)C)C(C)C -US20020082280A1,2,CC(=O)Nc1ccc(C(=O)O)cc1[N+](=O)[O-].CCCCS(N)(=O)=O>>CCCCS(=O)(=O)NC(=O)c1ccc(NC(C)=O)c([N+](=O)[O-])c1 -US04804668,9,Cc1nc(C(N)=O)sc1-c1ccncc1>>Cc1nc(C#N)sc1-c1ccncc1 -US05201935,3,CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(C2CCCCO2)no1>>CC(=O)C=Cc1cc(C2CCCCO2)no1 -US20100240638A1,6,COC(=O)[C@@H]1C[C@@H](Oc2noc3cc(Cl)ccc23)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C[C@H](Oc2noc3cc(Cl)ccc23)C[C@H]1C(=O)O -US20130030031A1,1,CN(C)C(=O)CCl.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCC(=O)N(C)C)cc1 -US20070167436A1,2,C1CCC(N2CCNCC2)C1.CCOC(=O)C1CCC(Nc2ccccc2F)CC1>>O=C(C1CCC(Nc2ccccc2F)CC1)N1CCN(C2CCCC2)CC1 -US20070244170A1,4,CC(=O)CCC(C)=O.NCc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>Cc1ccc(C)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US07087635B2,1,CC(C)(Cc1c[nH]c2c(O)cccc12)NC(=O)OC(C)(C)C.COC(=O)c1ccc(Cl)nc1>>COC(=O)c1ccc(Oc2cccc3c(CC(C)(C)NC(=O)OC(C)(C)C)c[nH]c23)nc1 -US06214992B1,1,BrCc1ccccc1.CCCCn1c(=O)[nH]c(=O)c2[nH]cnc21>>CCCCn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1 -US20100267696A1,2,CC(=O)Cl.O=C(c1csc(C2CCNCC2)c1)N1CCC[C@@H]2CCCC[C@@H]21>>CC(=O)N1CCC(c2cc(C(=O)N3CCC[C@@H]4CCCC[C@@H]43)cs2)CC1 -US07714168B2,1,C#CCBr.COc1cc(C(=O)NC(C)(C)C(C)C)ccc1O>>C#CCOc1ccc(C(=O)NC(C)(C)C(C)C)cc1OC -US20100204228A1,3,CCN(CC)S(=O)(=O)c1ccc(Br)cc1.Cn1c(C#N)ccc1B(O)O>>CCN(CC)S(=O)(=O)c1ccc(-c2ccc(C#N)n2C)cc1 -US04816452,6,CCOC(=O)/C(=N\OC(C)(C)[C@@H]1CC[C@@H](C)CC1)c1csc(N)n1>>C[C@@H]1CC[C@@H](C(C)(C)O/N=C(\C(=O)O)c2csc(N)n2)CC1 -US07247633B2,1,Clc1cncc(N2CCNCC2)n1.OCc1ccsc1>>c1cc(COc2cncc(N3CCNCC3)n2)cs1 -US06936736B2,3,CC(C)(C=O)NC(=O)c1ccc(F)cc1F.C[Mg+]>>CC(O)C(C)(C)NC(=O)c1ccc(F)cc1F -US03991045,2,CCCCCCCCC(=O)OC(=O)CCCCCCCC.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1>>CCCCCCCCC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1 -US06159902,10,Br.C=CCCC(=O)C(C)(C)N1COC(C)=C(c2ccccc2)C1=O>>CC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)CCC(C)Br)CO1 -US07655641B2,1,BrCc1ccccc1.CSc1ccc(O)cc1C>>CSc1ccc(OCc2ccccc2)cc1C -US20110190309A1,1,O=C(CBr)Nc1cnccn1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3ccccc3)CCCCCC1)C2)Nc1cnccn1 -US20080312227A1,3,CC(C)Oc1nc(NC(=O)C(C)(C)C)nc2ncc(Br)cc12.Cc1ccc(B(O)O)cc1C>>Cc1ccc(-c2cnc3nc(NC(=O)C(C)(C)C)nc(OC(C)C)c3c2)cc1C -US20090291950A1,1,COc1ccc2c(Br)coc2c1OC1CCCC1.Nc1c(Cl)cncc1Cl>>COc1ccc2c(Nc3c(Cl)cncc3Cl)coc2c1OC1CCCC1 -US20110014154A1,6,COC(=O)c1ccc2c(c1)-c1cc3c(C4CCCCC4)cccc3n1C=C1N=C(C)CN12>>CC1=NC2=Cn3c(cc4c(C5CCCCC5)cccc43)-c3cc(C(=O)O)ccc3N2C1 -US08309581B2,1,COC(=O)c1ccccc1CBr.N#Cc1ccc(O)c(F)c1>>COC(=O)c1ccccc1COc1ccc(C#N)cc1F -US20150225412A1,1,CC(C)(C)OC(=O)N1CCCC(N)C1.O=[N+]([O-])c1ccccc1F>>CC(C)(C)OC(=O)N1CCCC(Nc2ccccc2[N+](=O)[O-])C1 -US03941803,1,NN.Nc1ccc(C(F)(F)F)cc1C(=O)c1ccccc1>>NN=C(c1ccccc1)c1cc(C(F)(F)F)ccc1N -US20050148648A1,2,COc1ccc(C2(CN)CCCC2)cc1OC.O=C(O)CSc1ccccc1>>COc1ccc(C2(CNC(=O)CSc3ccccc3)CCCC2)cc1OC -US20140357858A1,2,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=C(Cl)c1ccc(Cl)cc1Cl>>O=C1CC(=O)N(c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)c2ccc3ccccc3c2N1 -US20120214788A1,2,COC(=O)C1CNCC(c2ccc(C)c(C)c2)C1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COC(=O)C1CC(c2ccc(C)c(C)c2)CN(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1 -US06172085B2,1,OC1CCNCC1.OC1c2ccccc2-c2ccccc21>>c1ccc2c(c1)-c1ccccc1C2OC1CCNCC1 -US20090270456A1,3,COC(=O)c1sc(Cl)nc1Cl.COc1cccc(B(O)O)c1>>COC(=O)c1sc(-c2cccc(OC)c2)nc1Cl -US04241058,1,CC(C=O)Cc1ccc(C(C)(C)C)cc1.CC1CNCC(C)C1>>CC(Cc1ccc(C(C)(C)C)cc1)CN1CC(C)CC(C)C1 -US04330539,7,CN[C@H]1[C@H](O)C[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C>>CN[C@H]1[C@H](O)C[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C -US06774248B2,3,C=CC(N)=O.Oc1ccc(-c2cc3cc(O)cc(Br)c3o2)cc1>>NC(=O)C=Cc1cc(O)cc2cc(-c3ccc(O)cc3)oc12 -US20120095061A1,1,BrCc1ccccc1.Cn1c(C(O)C(F)(F)F)cc(=O)c(O)c1CO>>Cn1c(C(O)C(F)(F)F)cc(=O)c(OCc2ccccc2)c1CO -US20040198982A1,1,COC(=O)C(Br)CC(C)C.OCc1ccc(Br)cc1>>COC(=O)C(CC(C)C)OCc1ccc(Br)cc1 -US09126957B2,6,CN(C)C1=N[C@H]2[C@H](C[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)S1>>CN(C)C1=N[C@H]2[C@H](C[C@H](CO)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)S1 -US20040229858A1,6,CCOC(=O)c1ccc(CCCN(C)C(=O)Cc2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)cc1>>COc1cc(CC(=O)N(C)CCCc2ccc(C(=O)O)cc2)ccc1NC(=O)Nc1ccccc1C -US20090258882A1,9,COc1ccc(-c2nc(Cl)nc3ccc(Br)cc23)cc1OC.N>>COc1ccc(-c2nc(N)nc3ccc(Br)cc23)cc1OC -US20150210710A1,2,CS(=O)(=O)CC(=O)O.FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CN=C(c2ccc3c(c2)COC32CNC2)C1>>CS(=O)(=O)CC(=O)N1CC2(C1)OCc1cc(C3=NCC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)ccc12 -US08916557B2,1,CCCO.CS(=O)(=O)Cc1cccc(Nc2ncnc(-c3ccc(F)cc3F)n2)c1>>CCCOc1cc(F)ccc1-c1ncnc(Nc2cccc(CS(C)(=O)=O)c2)n1 -US08691991B2,2,CC(CO)NC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN)c1=O.O=C(Cl)N1CCOCC1>>CC(CO)NC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCNC(=O)N2CCOCC2)c1=O -US20060094767A1,2,O=C=Nc1ccc(Cl)cc1.O=[N+]([O-])c1cn2c(n1)OC(CCO)C2>>O=C(Nc1ccc(Cl)cc1)OCCC1Cn2cc([N+](=O)[O-])nc2O1 -US20070249630A1,1,NCc1ccccc1.O=[N+]([O-])c1cc(I)ccc1F>>O=[N+]([O-])c1cc(I)ccc1NCc1ccccc1 -US05935972,6,Cc1cc(NC(=O)C(F)(F)F)cc2ccoc12>>Cc1cc(N)cc2ccoc12 -US20060178377A1,3,CC(=O)CC(N)=O.O=Cc1ccc(Cl)cc1Cl>>CC(=O)C(=Cc1ccc(Cl)cc1Cl)C(N)=O -US20120004216A1,4,NC(N)=S.O=C(CBr)c1ccccc1>>Nc1nc(-c2ccccc2)cs1 -US20150183778A1,6,COC(=O)C1=C(C(=O)Nc2sc(C)c(C3CC3)c2-c2nc(C(F)(F)F)no2)CCC1>>Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C(F)(F)F)no2)c1C1CC1 -US20070082892A1,2,CC(C)(C)C(=O)CN1C(=O)N(CC(=O)O)C(=O)N(C2CCCCC2)c2ccccc21.CN(c1cccc(N)c1)c1nn[nH]n1>>CN(c1cccc(NC(=O)CN2C(=O)N(CC(=O)C(C)(C)C)c3ccccc3N(C3CCCCC3)C2=O)c1)c1nn[nH]n1 -US20150191432A1,1,C1COCCN1.Oc1cccc2ccc(Cl)nc12>>Oc1cccc2ccc(N3CCOCC3)nc12 -US20140275067A1,6,CC(C)(C)OC(=O)NC[C@@H](NC(=O)OCc1ccccc1)C(C)(C)C>>CC(C)(C)OC(=O)NC[C@@H](N)C(C)(C)C -US20030139449A1,6,COc1ccccc1N1CCN(C(=O)[C@@H](CC2CCCCC2)NC(=O)OC(C)(C)C)CC1>>COc1ccccc1N1CCN(C(=O)[C@H](N)CC2CCCCC2)CC1 -US05723408,2,CCS(=O)(=O)Cl.CCn1ncc(C(=O)c2cc(C)c3c(c2C)C(C)(C)CCS3(=O)=O)c1O>>CCn1ncc(C(=O)c2cc(C)c3c(c2C)C(C)(C)CCS3(=O)=O)c1OS(=O)(=O)CC -US20090215778A1,7,CC(=O)c1cccc(C#N)c1>>C[C@@H](O)c1cccc(C#N)c1 -US20120129793A1,6,CC1(C)NC(C)(C)N(CCCCOCc2ccccc2)C1=O>>CC1(C)NC(C)(C)N(CCCCO)C1=O -US20130040930A1,1,Cc1cc(C)c(N2CCN(C(=O)c3ccc(Br)cc3C#N)CC2)nc1C.O=C1CCCN1>>Cc1cc(C)c(N2CCN(C(=O)c3ccc(N4CCCC4=O)cc3C#N)CC2)nc1C -US04092150,1,CC(C)Nc1nc(Cl)c(C#N)c(NC2CC2)n1.C[O-]>>COc1nc(NC(C)C)nc(NC2CC2)c1C#N -US20100217000A1,6,C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2c1sc(=O)n2C1CCCCO1>>C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)sc12 -US08334292B1,1,CC(C)(C)OC(=O)N1CC(COc2nc(Cl)ncc2Br)C1.C[C@@H]1CC[C@H](N)CC1>>C[C@H]1CC[C@@H](Nc2ncc(Br)c(OCC3CN(C(=O)OC(C)(C)C)C3)n2)CC1 -US20100256092A1,7,N#Cc1cccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c1>>NCc1cccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c1 -US20100256356A1,6,COc1ccc(Cn2nc(C)c3c(Oc4ccc(-c5cnc(Nc6ccccc6)n(C)c5=O)cc4F)ccnc32)cc1>>Cc1n[nH]c2nccc(Oc3ccc(-c4cnc(Nc5ccccc5)n(C)c4=O)cc3F)c12 -US04160036,3,CC(=O)CCc1ccc(F)cc1.C[Mg+]>>CC(C)(O)CCc1ccc(F)cc1 -US20020103203A1,2,Cc1cc(N)ccc1C(C)C.O=C(O)c1cccc(SCc2cnccn2)c1>>Cc1cc(NC(=O)c2cccc(SCc3cnccn3)c2)ccc1C(C)C -US06030952,7,C=C(C(=O)OC)c1ccc2c(c1)C(C)(C)CCC2(C)C>>C=C(CO)c1ccc2c(c1)C(C)(C)CCC2(C)C -US04054591,7,CCOC(=O)C(=O)Nc1cccc([N+](=O)[O-])c1C#N>>CCOC(=O)C(=O)Nc1cccc(N)c1C#N -US08563565B2,1,CC(C)(C)OC(=O)NN.O=C1CCOC1>>CC(C)(C)OC(=O)NN=C1CCOC1 -US20110207704A1,1,CC(C)Oc1ccc(-c2noc(-c3ccc4[nH]ccc4c3)n2)cc1Cl.COC(=O)C1CCC(Br)C1>>COC(=O)C1CCC(n2ccc3cc(-c4nc(-c5ccc(OC(C)C)c(Cl)c5)no4)ccc32)C1 -US20120283254A1,2,CCc1ccc(C(=O)O)cc1.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CCc1ccc(C(=O)N[C@@H]2CC[C@@H](CCN3CCCCC3c3coc4cccc-4c3)CC2)cc1 -US08188101B2,4,COc1cc(NC(=N)N)ccc1-n1cnc(C)c1.Cc1cc(C)n(C(C)C(=O)C2CN(C(=O)OC(C)(C)C)CCC2=O)n1>>COc1cc(Nc2nc3c(c(C(C)n4nc(C)cc4C)n2)CN(C(=O)OC(C)(C)C)CC3)ccc1-n1cnc(C)c1 -US20030176495A1,1,CC1(C)OC(=O)C(=CC(=O)Cl)O1.CONCc1ccc(Cl)cc1>>CON(Cc1ccc(Cl)cc1)C(=O)C=C1OC(C)(C)OC1=O -US05298503,1,CNCC1CCN(Cc2ccccc2)CC1.O=C(CCCI)c1ccc(F)cc1>>CN(CCCC(=O)c1ccc(F)cc1)CC1CCN(Cc2ccccc2)CC1 -US20140011881A1,2,CCOc1cc(C(F)(F)F)ccc1C(=O)O.CNOC>>CCOc1cc(C(F)(F)F)ccc1C(=O)N(C)OC -US05952382,8,COCCOCOc1cc2ccc(-c3ccc(CO)cc3)cc2cc1C12CC3CC(CC(C3)C1)C2>>COCCOCOc1cc2ccc(-c3ccc(C=O)cc3)cc2cc1C12CC3CC(CC(C3)C1)C2 -US20110237573A1,2,CC(=O)N1CCN(c2ccc(N)nc2)CC1.O=C(O)Cc1ccc(-c2ccnc(F)c2)nc1>>CC(=O)N1CCN(c2ccc(NC(=O)Cc3ccc(-c4ccnc(F)c4)nc3)nc2)CC1 -US20150250794A1,4,COc1ccc(C(=O)CBr)cc1.NC(N)=S>>COc1ccc(-c2csc(N)n2)cc1 -US04782176,1,BrCCOCCOCCOCCBr.CCCc1c(OCCCC(=O)OCC)ccc(C(C)=O)c1O>>CCCc1c(OCCCC(=O)OCC)ccc(C(C)=O)c1OCCOCCOCCOCCBr -US06288086B1,6,CCOC(=O)C1(S(=O)(=O)c2ccc(OCCC(C)C)cc2)CCN(Cc2ccccc2)CC1>>CC(C)CCOc1ccc(S(=O)(=O)C2(C(=O)O)CCN(Cc3ccccc3)CC2)cc1 -US20150210669A1,1,CCOC(=O)C1CCNCC1.Cc1ccc(-c2cc(Br)ccc2Cl)nc1>>CCOC(=O)C1CCN(c2ccc(Cl)c(-c3ccc(C)cn3)c2)CC1 -US20100004238A1,6,COC(=O)c1cncc(Oc2ccc([N+](=O)[O-])cc2Cl)c1>>O=C(O)c1cncc(Oc2ccc([N+](=O)[O-])cc2Cl)c1 -US05326900,3,COC(=O)c1ccc(CBr)cc1.COc1cc(C(=O)Cl)cc2c1C(C)(C)CCC2(C)C>>COC(=O)c1ccc(CC(=O)c2cc(OC)c3c(c2)C(C)(C)CCC3(C)C)cc1 -US20060287309A1,2,CC(C)(C)OC(=O)NCc1ccc(OCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)nc1N>>O=C1NCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)nc2N1 -US20080318923A1,2,COc1ccc(S(=O)(=O)Cl)c(OC(F)(F)F)c1.COc1ccccc1C1(N2CC(O)C(O)[C@H]2C(=O)N(C)C)C(=O)Nc2ccc(Cl)cc21>>COc1ccc(S(=O)(=O)N2C(=O)C(c3ccccc3OC)(N3CC(O)C(O)[C@H]3C(=O)N(C)C)c3cc(Cl)ccc32)c(OC(F)(F)F)c1 -US20130231328A1,2,CS(=O)(=O)Cl.OC[C@H]1CCc2sc3ncnc(OC4CCC(N5CC6(COC6)C5)CC4)c3c21>>CS(=O)(=O)OC[C@H]1CCc2sc3ncnc(OC4CCC(N5CC6(COC6)C5)CC4)c3c21 -US20040043995A1,1,CCOC(=O)C(C)=O.CCc1ccc(NN)cc1>>CCOC(=O)C(C)=NNc1ccc(CC)cc1 -US07741329B2,6,CC(C)(C)OC(=O)N1CCCC[C@H]1CNC(=O)C(F)(F)F>>CC(C)(C)OC(=O)N1CCCCC1CN -US20150225389A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](C)(C)N1C(=O)[C@H](Cc2cnc(N)s2)[C@H]1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)Nc1ncc(C[C@H]2C(=O)N([Si](C)(C)C(C)(C)C)[C@@H]2C(=O)OCc2ccccc2)s1 -US20140249157A1,1,C1CNCCN1.Fc1cncc(Cl)c1I>>Fc1cncc(Cl)c1N1CCNCC1 -US05212173,9,CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OCCN(C)CCCl.[N-]=[N+]=[N-]>>CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OCCN(C)CCN=[N+]=[N-] -US20090137609A1,6,CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)c(F)c2)c(C)c1>>CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)O)c(F)c2)c(C)c1 -US20050272763A1,6,CCN(CC)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)C(F)(F)F>>CCN(CC)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1N -US20040137263A1,1,CCCCC(CC)CBr.Oc1ccc(Br)cc1>>CCCCC(CC)COc1ccc(Br)cc1 -US20150225449A1,1,C[C@@H](C(=O)N[C@@H]1C(=O)Nc2ccccc2N(C(=O)C2CCOCC2)[C@H]1C)N(C)C(=O)OC(C)(C)C.N#Cc1ccccc1-n1nc(CBr)c2ccccc21>>C[C@@H](C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2N(C(=O)C2CCOCC2)[C@H]1C)N(C)C(=O)OC(C)(C)C -US20150191495A1,7,CCOC(=O)/C=C/c1cc(OC)ncc1C(=O)OC>>CCOC(=O)CCc1cc(OC)ncc1C(=O)OC -US20090149445A1,7,O=Cc1ccccc1C=C1c2ccccc2CCc2ccccc21>>OCc1ccccc1C=C1c2ccccc2CCc2ccccc21 -US20050192347A1,6,CC(C)(CO)CCCCN1C(=O)c2ccccc2C1=O>>CC(C)(CO)CCCCN -US05246961,1,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](Br)SC[C@H]1OC(C)=O.O=[N+]([O-])c1ccccc1S>>CC(=O)O[C@H]1[C@H](Sc2ccccc2[N+](=O)[O-])SC[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US20070185133A1,3,Cc1ccc(B(O)O)s1.Clc1ccnc(Cl)n1>>Cc1ccc(-c2ccnc(Cl)n2)s1 -US20120270838A1,7,COC(=O)CN(C)c1ccc(Br)c(C(F)(F)F)c1>>CN(CCO)c1ccc(Br)c(C(F)(F)F)c1 -US20070173548A1,7,COc1ccc(Oc2c(C)cc([N+](=O)[O-])cc2C)cc1C(=O)CC1CCCC1>>COc1ccc(Oc2c(C)cc([N+](=O)[O-])cc2C)cc1CCC1CCCC1 -US20110301161A1,1,CC(C)(C)n1c(-c2cc(O)ccc2-n2cncn2)nc2cc(-c3cnc(N)nc3)ccc21.CCI>>CCOc1ccc(-n2cncn2)c(-c2nc3cc(-c4cnc(N)nc4)ccc3n2C(C)(C)C)c1 -US08124809B2,3,Brc1ccccc1.C=Cc1ccc([Mg+])cc1>>C=Cc1ccc(-c2ccccc2)cc1 -US05675023,6,COc1ccc(S)cc1Cl>>Oc1ccc(S)cc1Cl -US20100016396A1,2,COC(=O)[C@@H](C)O.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)[C@@H](C)OS(=O)(=O)c1ccc(C)cc1 -US05204358,1,CC(C)(C)[Si](OCc1cccc(C(Cl)c2cccc(OCc3ccc4ccc(Cl)cc4n3)c2)c1)(c1ccccc1)c1ccccc1.CN(C)C(=O)CCS>>CN(C)C(=O)CCSC(c1cccc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 -US20060166993A1,2,COc1cc(Nc2nc(-c3cccc(N)c3)nn3c(C)nc(C)c23)cc(OC)c1OC.CS(=O)(=O)Cl>>COc1cc(Nc2nc(-c3cccc(NS(C)(=O)=O)c3)nn3c(C)nc(C)c23)cc(OC)c1OC -US20120115841A1,8,CC(O)c1cnc(Br)s1>>CC(=O)c1cnc(Br)s1 -US06479490B2,6,COC(=O)Cc1cccc(OC[C@@H]2COC(C)(C)O2)c1[N+](=O)[O-]>>CC1(C)OC[C@@H](COc2cccc(CC(=O)O)c2[N+](=O)[O-])O1 -US04150025,4,C/C=C/C=O.Nc1ccccc1Cl>>Cc1ccc2cccc(Cl)c2n1 -US06989401B2,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.CN>>CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C -US20100063081A1,2,CC(C)(C)OC(=O)N1CCC(CCCCc2ccc(N)cc2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(CCCCc2ccc(NS(C)(=O)=O)cc2)CC1 -US04599198,1,CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@H](C=O)OCc1ccccc1.CC(C)C[NH3+]>>CC(C)CNC[C@@H](OCc1ccccc1)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C -US20070054916A1,2,CC(C)c1cccc(C(=O)O)c1.Cc1ccc(N)cc1-c1ccc2nc(N)ncc2c1>>Cc1ccc(NC(=O)c2cccc(C(C)C)c2)cc1-c1ccc2nc(N)ncc2c1 -US07538131B2,6,CCc1oc(-c2ccc(C(F)(F)F)cc2)nc1COC[C@@H]1CCC[C@H](COC(C)(C)C(=O)OC(C)(C)C)C1>>CCc1oc(-c2ccc(C(F)(F)F)cc2)nc1COC[C@@H]1CCC[C@H](COC(C)(C)C(=O)O)C1 -US05258392,1,Fc1ccccc1C(F)(F)F.OC1CN2CCC1CC2>>FC(F)(F)c1ccccc1OC1CN2CCC1CC2 -US08097627B2,2,CCO.COc1c(C(C)(C)CC(=O)C(=O)O)ccc(Cl)c1F>>CCOC(=O)C(=O)CC(C)(C)c1ccc(Cl)c(F)c1OC -US05801168,3,CCCC[Sn](CCCC)(CCCC)c1ccc([N+](=O)[O-])cc1.COc1c(I)c(=O)c2ccc(Cl)cc2[nH]c1=O>>COc1c(-c2ccc([N+](=O)[O-])cc2)c(=O)c2ccc(Cl)cc2[nH]c1=O -US20140349970A1,5,CC(=O)c1ccc(I)cc1.OCCO>>CC1(c2ccc(I)cc2)OCCO1 -US06380205B1,6,CCOC(=O)C1CCC(Cc2nc3ccccc3c(=O)[nH]2)CC1>>O=C(O)C1CCC(Cc2nc3ccccc3c(=O)[nH]2)CC1 -US20090131502A1,2,CC(C)CC(O)CCc1cccs1.CS(=O)(=O)Cl>>CC(C)CC(CCc1cccs1)OS(C)(=O)=O -US07625932B2,2,CCOC(=O)c1c(-c2ccc(C(=O)O)cc2)c(C#N)c(CC)n1C.Nc1ccccc1>>CCOC(=O)c1c(-c2ccc(C(=O)Nc3ccccc3)cc2)c(C#N)c(CC)n1C -US09120788B2,1,Nc1cc(F)c(Cl)c(F)c1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1Nc1cc(F)c(Cl)c(F)c1 -US20050065164A1,1,CCC1(C)CN(Cc2ccccc2)CCC1=O.[NH4+]>>CCC1(C)CN(Cc2ccccc2)CCC1N -US20080096892A1,7,O=C(O)COc1cccc([N+](=O)[O-])c1>>Nc1cccc(OCC(=O)O)c1 -US06271248B1,3,CC(C)[Mg+].O=Cc1ccc(Br)cc1>>CC(C)C(O)c1ccc(Br)cc1 -US08106057B2,2,CC(C)c1cc(C(=O)Cl)c(OCc2ccccc2)cc1OCc1ccccc1.CN(C)CCN1CCNCC1>>CC(C)c1cc(C(=O)N2CCN(CCN(C)C)CC2)c(OCc2ccccc2)cc1OCc1ccccc1 -US20090023753A1,2,CN=C=O.Nc1cc(CCl)ccn1>>CNC(=O)Nc1cc(CCl)ccn1 -US20080096240A1,1,BrCc1ccccc1.OCC1C2CCC(O2)C1Cc1cc(F)ccc1O>>OCC1C2CCC(O2)C1Cc1cc(F)ccc1OCc1ccccc1 -US20070167488A1,3,COc1ccc(CN(C)C)cc1C=O.O=C1Cc2ccccc2N1>>COc1ccc(CN(C)C)cc1C=C1C(=O)Nc2ccccc21 -US20140038941A1,2,CC(C)(C)c1nc2nc(C(=O)O)ccn2c1CC1CCCCC1.Nc1ccccc1>>CC(C)(C)c1nc2nc(C(=O)Nc3ccccc3)ccn2c1CC1CCCCC1 -US20150266881A1,3,CCOP(=O)(CC(=O)OC(C)(C)C)OCC.COC(=O)c1ccc(C)c(C=O)c1>>COC(=O)c1ccc(C)c(/C=C/C(=O)OC(C)(C)C)c1 -US20090137557A1,1,C=O.Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc2c(c1)CCCN2>>Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc2c(c1)CCCN2C -US20140171430A1,2,O=C(O)c1ccccc1-c1cccc(Cl)c1.c1ccc2nc(N3CC4CNCC4C3)cnc2c1>>O=C(c1ccccc1-c1cccc(Cl)c1)N1CC2CN(c3cnc4ccccc4n3)CC2C1 -US04724236,2,C#CCNC.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>C#CCN(C)C(=O)N1c2ccccc2C(=O)Nc2cccnc21 -US07160887B1,7,C[C@H](NC(=O)OC(C)(C)C)c1cccc(Oc2cc(Cl)ccc2[N+](=O)[O-])c1>>C[C@H](NC(=O)OC(C)(C)C)c1cccc(Oc2cc(Cl)ccc2N)c1 -US07217717B2,6,COc1cc2ncnc(Nc3ccc(Cl)cc3)c2cc1OC(C)=O>>COc1cc2ncnc(Nc3ccc(Cl)cc3)c2cc1O -US20120022100A1,9,COCCCOc1cc(C[C@@H](C[C@H](N=[N+]=[N-])[C@@H](O)C[C@H](C(=O)N[C@@H]2CCN(C)C2)C(C)C)C(C)C)ccc1OC>>COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@H](C(=O)N[C@@H]2CCN(C)C2)C(C)C)C(C)C)ccc1OC -US20150057271A1,6,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCCN3c2ccccc2C(O)CO)cc1>>O=S(=O)(Nc1nccs1)c1ccc2c(c1)OCCN2c1ccccc1C(O)CO -US20080076758A1,1,CC1(C)CNCCN1S(C)(=O)=O.O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CC1(C)CN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CCN1S(C)(=O)=O -US06060488,1,CCCCCCN1CCCC(CO)C1.COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(O)cc2)cc1>>CCCCCCN1CCCC(COc2ccc(C(=O)c3c(-c4ccc(OC)cc4)sc4cc(OC)ccc34)cc2)C1 -US08327467B2,6,COC(=O)c1ccc(SCc2ccccc2)cc1Nc1ccc(F)cc1>>O=C(O)c1ccc(SCc2ccccc2)cc1Nc1ccc(F)cc1 -US09108939B2,3,CC(=O)Nc1ccc(C(=O)C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1.C[Mg+]>>CC(=O)Nc1ccc(C(C)(O)C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1 -US20150158815A1,3,NC(=O)C(Nc1cncc(Br)c1)c1ccccc1.OB(O)c1cc(Cl)ccc1F>>NC(=O)C(Nc1cncc(-c2cc(Cl)ccc2F)c1)c1ccccc1 -US06413983B1,7,CCOC(=O)c1cc2ccccc2[nH]1>>CCOC(=O)C1Cc2ccccc2N1 -US20060241145A1,2,CC(=O)NCC(=O)O.COc1ccc(-n2nnnc2C(F)(F)F)cc1CN[C@H]1CCNC[C@H]1c1ccccc1>>COc1ccc(-n2nnnc2C(F)(F)F)cc1CN[C@H]1CCN(C(=O)CNC(C)=O)C[C@H]1c1ccccc1 -US06432993B1,1,CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-].Oc1ccc(Oc2ccccc2)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(Oc3ccccc3)cc2)ccc1[N+](=O)[O-] -US04091023,1,Clc1ccc2c(c1)CC(N1CCNCC1)c1ccccc1O2.O=C1OCCN1CCCl>>O=C1OCCN1CCN1CCN(C2Cc3cc(Cl)ccc3Oc3ccccc32)CC1 -US20140163025A1,6,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(O[Si](C)(C)C(C)(C)C)c(C#N)c5)ccc(F)c43)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(O)c(C#N)c5)ccc(F)c43)ccc21 -US20140243336A1,1,CSCCC(CO)NC(=O)OC(C)(C)C.O=C1NC(=O)c2ccccc21>>CSCCC(CN1C(=O)c2ccccc2C1=O)NC(=O)OC(C)(C)C -US05384078,3,Cc1ccc(Cl)cc1.O=C(Cl)c1ccccc1>>Cc1ccc(C(=O)c2ccccc2)cc1 -US07285563B2,7,O=[N+]([O-])c1cccc2c(Cl)nccc12>>Nc1cccc2c(Cl)nccc12 -US04273704,2,COC(=O)CN.C[C@@H](NC(=O)OC(C)(C)C)C(=O)O>>COC(=O)CNC(=O)[C@@H](C)NC(=O)OC(C)(C)C -US08129376B2,6,CCOC(=O)c1cc2sc(-c3ccccc3)cc2[nH]1>>O=C(O)c1cc2sc(-c3ccccc3)cc2[nH]1 -US20080269255A1,7,CC(C)(C)OC(=O)C1(Cc2ccccc2)CC1>>OCC1(Cc2ccccc2)CC1 -US04642345,1,ClCc1ccc(Cl)cc1.NCCN>>NCCNCc1ccc(Cl)cc1 -US20130053373A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](CO)C[C@H]2CS1>>CC(C)(C)OC(=O)NC1=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](CO)C[C@H]2CS1 -US20150224071A1,6,CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F>>O=C(O)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F -US06211170B1,8,O=C1C[C@H](CSc2ccccc2)N1.O=S([O-])OO>>O=C1C[C@H](CS(=O)c2ccccc2)N1 -US05821261,2,CC(C)(C)OC(=O)[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)[C@@H]1C[C@H](OS(C)(=O)=O)CN1C(=O)OC(C)(C)C -US20140171404A1,1,CC(C)(C)OC(=O)NCCC1CN(C(=O)OCc2cc(Cl)cc(Cl)c2)CCO1.CI>>CN(CCC1CN(C(=O)OCc2cc(Cl)cc(Cl)c2)CCO1)C(=O)OC(C)(C)C -US07592353B2,1,C#CC(C)(C)O.C1=COCCC1>>C#CC(C)(C)OC1CCCCO1 -US08937092B2,2,CS(=O)(=O)Cl.NCc1ccc([N+](=O)[O-])cc1F>>CS(=O)(=O)NCc1ccc([N+](=O)[O-])cc1F -US20150272928A1,7,O=Cc1c(-c2ccccc2)[nH]c2ccccc12>>OCc1c(-c2ccccc2)[nH]c2ccccc12 -US20100075924A1,2,CC(=O)OC(C)=O.N[C@H]1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1COC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=O)N[C@H]1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1COC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20110124642A1,2,Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O.O=C(O)Cc1ccc(Cl)cc1>>O=C(Cc1ccc(Cl)cc1)Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O -US20120289500A1,2,CC(C)COC(=O)Cl.NCc1nn(NC(=O)Cc2ccc(Cl)cc2)c(=O)c2ccccc12>>CC(C)COC(=O)NCc1nn(NC(=O)Cc2ccc(Cl)cc2)c(=O)c2ccccc12 -US20100152188A1,2,CO.Nc1nc(CC(=O)O)cs1>>COC(=O)Cc1csc(N)n1 -US20140142119A1,2,CC1(C(=O)O)CC1.Fc1cnc(-c2c[nH]c3ncc(Cl)cc23)nc1N[C@H]1CCCNC1>>CC1(C(=O)N2CCC[C@H](Nc3nc(-c4c[nH]c5ncc(Cl)cc45)ncc3F)C2)CC1 -US20100249163A1,6,COCCCn1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(F)c(F)c2)C2CC2)c2ccccc21>>COCCCn1cc(CN(C(=O)C2CNCCC2(O)c2ccc(F)c(F)c2)C2CC2)c2ccccc21 -US20090062282A1,1,CI.CN(C)C=NC1=NC(C)(c2ccc(Cl)c(Cl)c2)CC(=O)N1>>CN(C)C=NC1=NC(C)(c2ccc(Cl)c(Cl)c2)CC(=O)N1C -US08304557B2,2,CC(C)CC(=O)Cl.Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)cc1N>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)cc1NC(=O)CC(C)C -US20090048258A1,2,Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1.O=C(O)CCC(=O)c1ccc2c(c1)OCCCO2>>O=C(CCC(=O)c1ccc2c(c1)OCCCO2)Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1 -US20060264415A1,2,CC(=O)OC(C)=O.Nc1nc(CCCCCNC(=O)COCc2ccc(F)cc2)cs1>>CC(=O)Nc1nc(CCCCCNC(=O)COCc2ccc(F)cc2)cs1 -US06472393B1,6,COc1cc(C(CN2C(=O)c3ccccc3C2=O)Nc2ccc(C#N)cc2)c([N+](=O)[O-])cc1OCc1ccccc1>>COc1cc(C(CN)Nc2ccc(C#N)cc2)c([N+](=O)[O-])cc1OCc1ccccc1 -US06962923B2,1,CCOCCBr.Cc1ccc(-c2c(O)nn(C)c2N)cc1>>CCOCCOc1nn(C)c(N)c1-c1ccc(C)cc1 -US05039333,8,COC(=O)c1cc(CSc2ccccc2)cnc1C1=NC(C)(C(C)C)C(=O)N1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1cc(CS(=O)c2ccccc2)cnc1C1=NC(C)(C(C)C)C(=O)N1 -US20150105317A1,9,[N-]=[N+]=NCCC[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>NCCC[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US20120264750A1,1,Cc1cn[nH]c1.Fc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1>>Cc1cnn(-c2cnccc2-c2nc3cc(C(F)(F)F)ccc3o2)c1 -US07262186B2,1,CCC(Br)c1nc2[nH]nc(Br)c2c(=O)n1Cc1ccccc1.CN(C)CCN>>CCC(NCCN(C)C)c1nc2[nH]nc(Br)c2c(=O)n1Cc1ccccc1 -US20060063772A1,7,CCOC(=O)c1cc(-c2cc(Cl)ccc2F)on1>>OCc1cc(-c2cc(Cl)ccc2F)on1 -US06204221B1,3,C=C[Sn](CCCC)(CCCC)CCCC.Cn1nc(-c2nc(Cl)c(Cl)cc2F)c(Cl)c1OC(F)F>>C=Cc1nc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl -US20060046984A1,6,CC[C@@H](C)[C@@]1(NC(C)=O)CCN([C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)[C@H]2C[C@H](Oc3ccccn3)CN2C(c2ccccc2)c2ccccc2)C1=O>>CC[C@@H](C)[C@@]1(NC(C)=O)CCN([C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)[C@H]2C[C@@H](Oc3ccccn3)CN2)C1=O -US05272145,1,BrCc1ccc2ccccc2n1.COC(=O)C(C)(C)Cc1c(Cc2ccc(Cl)cc2)c2ccc(O)cc2n1C>>COC(=O)C(C)(C)Cc1c(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc2n1C -US20060111351A1,2,CC(C)(c1ccc(S(=O)(=O)Cl)cc1)c1cocn1.Nc1ccc(Cl)cc1C(=O)c1ccncc1>>CC(C)(c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2ccncc2)cc1)c1cocn1 -US06451836B1,1,BrCC1CC1.c1ccc(COC[C@H]2NC[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1>>c1ccc(COC[C@@H]2[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)CN2CC2CC2)cc1 -US20110263571A1,2,Cc1cc(C2CC2)cnc1N1CCNCC1.O=C(O)c1ccc(Br)nc1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)nc2)CC1 -US20130231306A1,1,CN1Cc2c(C3CCC(O)CC3)ccc(N)c2C1=O.O=P1(Cc2ccc(Nc3ncc(C(F)(F)F)c(Cl)n3)cc2)OCCCO1>>CN1Cc2c([C@@H]3CC[C@@H](O)CC3)ccc(Nc3nc(Nc4ccc(CP5(=O)OCCCO5)cc4)ncc3C(F)(F)F)c2C1=O -US20050154061A1,1,Cc1cc(CNC2CCCCC2)ccc1OCC(=O)OC(C)(C)C.O=C(CBr)Nc1ccc(Cl)cc1Cl>>Cc1cc(CN(CC(=O)Nc2ccc(Cl)cc2Cl)C2CCCCC2)ccc1OCC(=O)OC(C)(C)C -US20090253680A1,2,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(CC(=O)O)CC3)CC2)cc(C)c1O.O=C1CCCN1CCO>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(CC(=O)OCCN4CCCC4=O)CC3)CC2)cc(C)c1O -US09120749B2,1,Nc1cncc(CCN2CCCC2)c1.O=C(c1cnc2ccc(Br)cc2c1Cl)C1CC1>>O=C(c1cnc2ccc(Br)cc2c1Nc1cncc(CCN2CCCC2)c1)C1CC1 -US20090306133A1,2,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1.O=S(=O)(Cl)c1ccc2ccccc2c1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNS(=O)(=O)c2ccc3ccccc3c2)CC1 -US08344135B2,1,CC(C)(C)OC(=O)Nc1cccc(NC2CC2)c1.N#CSc1nc(Cl)ncc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cccc(N(c2ncc([N+](=O)[O-])c(SC#N)n2)C2CC2)c1 -US20140357612A1,7,CCN(C)S(=O)(=O)Nc1cccc(C(=O)OC)c1F>>CCN(C)S(=O)(=O)Nc1cccc(CO)c1F -US05602277,6,CCOC(=O)c1ccc(NS(C)(=O)=O)cc1>>CS(=O)(=O)Nc1ccc(C(=O)O)cc1 -US05087697,1,CC(=O)Nc1nc(Cl)c(NC=O)c(Cl)n1.N[C@H]1C=C[C@@H](CO)C1>>CC(=O)Nc1nc(Cl)c(NC=O)c(N[C@@H]2C=C[C@H](CO)C2)n1 -US06395351B1,7,CCCCCOC(=O)c1cc(C2CCC(=O)CC2)ccc1O>>CCCCCOC(=O)c1cc([C@@H]2CC[C@@H](O)CC2)ccc1O -US20030149027A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(N)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)NC(C)(C)c1ccc([N+](=O)[O-])cc1 -US08183275B2,3,CC(C)(C)OC(=O)c1ccccc1I.CC1(C)OB(c2ccc(CCCO)cc2)OC1(C)C>>CC(C)(C)OC(=O)c1ccccc1-c1ccc(CCCO)cc1 -US06599916B2,2,N[C@H]1CN2CCC1CC2.O=C(O)c1ccc(Sc2ccc(Cl)cc2)s1>>O=C(N[C@H]1CN2CCC1CC2)c1ccc(Sc2ccc(Cl)cc2)s1 -US20070249670A1,6,COC(=O)[C@](C)(NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cc(OC(F)(F)F)cc1Cl)C1CCCCC1>>C[C@](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cc(OC(F)(F)F)cc1Cl)(C(=O)O)C1CCCCC1 -US20100145067A1,1,Ic1ccc(-n2c3ccccc3c3ccccc32)cc1.Nc1ccccc1>>c1ccc(Nc2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1 -US20080070885A1,2,CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](Cc1cccc(OCCCCCC(=O)O)c1)NC(=O)[C@H](C)[NH3+]>>CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H]1Cc2cccc(c2)OCCCCCC(=O)N[C@@H](C)C(=O)N1 -US20090093512A1,6,CC(C)(C)OC(=O)N1CC2Cn3c(cccc3=O)C2C1>>O=c1cccc2n1CC1CNCC21 -US08067408B2,2,CC(C)(C)OC(=O)N1CCN(Cc2cccc(-c3cccc(CN)c3)c2)CC1.CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccc(C(=O)O)cc1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccc(C(=O)NCc2cccc(-c3cccc(CN4CCN(C(=O)OC(C)(C)C)CC4)c3)c2)cc1 -US20080249318A1,1,Cc1ccc(Br)cc1.Cc1cccc(Cl)c1N>>Cc1ccc(Nc2c(C)cccc2Cl)cc1 -US04788186,1,CC[O-].Clc1ccc2c(c1)c(-c1ccccc1)nn1c(Cl)nnc21>>CCOc1nnc2c3ccc(Cl)cc3c(-c3ccccc3)nn12 -US09107916B2,1,N#Cc1ccnc(-n2nccc2O)c1.OCc1ccc(Cl)c(OCc2ccc(F)cc2)c1>>N#Cc1ccnc(-n2nccc2OCc2ccc(Cl)c(OCc3ccc(F)cc3)c2)c1 -US08299065B2,6,O=C(NC(=S)Nc1cc(Br)c(F)cc1F)c1ccccc1>>NC(=S)Nc1cc(Br)c(F)cc1F -US20130072520A2,9,COc1cccc(-c2nc(COc3ccc(F)c(C(N)=O)c3F)sc2Br)c1>>COc1cccc(-c2csc(COc3ccc(F)c(C(N)=O)c3F)n2)c1 -US05756754,2,CN=C=O.Oc1ccc2onc(NCCN3CCOCC3)c2c1>>CNC(=O)Oc1ccc2onc(NCCN3CCOCC3)c2c1 -US20090181942A1,6,CCOC(=O)C(=O)N1CCN(C(=O)CC(O)C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)CC1>>COc1cccc([C@H]2O[C@H](CC(O)CC(=O)N3CCN(C(=O)C(=O)O)CC3)c3cccn3-c3ccc(Cl)cc32)c1OC -US04883815,7,O=C1CCC2=C(CCc3cc(F)ccc32)N1>>Fc1ccc2c(c1)CCC1=C2CCCN1 -US06627651B1,1,CC(C)(C)OC(=O)NC1CCNCC1.O=C(NCCBr)OCc1ccccc1>>CC(C)(C)OC(=O)NC1CCN(CCNC(=O)OCc2ccccc2)CC1 -US20110319424A1,1,CC1(NCc2ccc(C(F)(F)F)nc2)CCNCC1.O=CCn1c(=O)ccc2ncc(F)cc21>>CC1(NCc2ccc(C(F)(F)F)nc2)CCN(CCn2c(=O)ccc3ncc(F)cc32)CC1 -US07482469B2,2,Cc1cccc(-c2cc(N)on2)c1.O=C(O)Cn1cnc2ccccc21>>Cc1cccc(-c2cc(NC(=O)Cn3cnc4ccccc43)on2)c1 -US06919339B2,2,CC(C)(C)c1ccc(C(=O)Cl)cc1.CSc1nc(N)cc(N)n1>>CSc1nc(N)cc(NC(=O)c2ccc(C(C)(C)C)cc2)n1 -US20130029980A1,1,BrCCOc1ccccc1.Cc1ccc(N)c([N+](=O)[O-])c1>>Cc1ccc(NCCOc2ccccc2)c([N+](=O)[O-])c1 -US05885990,1,COC(=O)c1c(O)ccc2cc(C(=N)N)ccc12.NN=CNc1ccc(C(=O)O)cc1>>COC(=O)c1c(OC(=O)c2ccc(NC=NN)cc2)ccc2cc(C(=N)N)ccc12 -US20050272784A1,1,C1CCNCC1.CC(C)(C)OC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)oc1-c1cccnc1Cl>>CC(C)(C)OC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)oc1-c1cccnc1N1CCCCC1 -US20140094462A1,6,CC(C)(C)OC(=O)N[C@@H]1CC=CCCC(=O)N[C@H](c2ccccc2)CCOC1=O>>N[C@@H]1CC=CCCC(=O)N[C@H](c2ccccc2)CCOC1=O -US07335660B2,1,CS(=O)(=O)OCC[C@@H]1OCCc2cc(N3CCNC3=O)ccc21.C[C@@H]1CN(c2csc3cc(C#N)ccc23)CCN1>>C[C@@H]1CN(c2csc3cc(C#N)ccc23)CCN1CC[C@@H]1OCCc2cc(N3CCNC3=O)ccc21 -US20150252008A1,1,CCc1ccc(-c2cnc(N)cn2)c(F)c1O.Nc1ccnc(Cl)n1>>CCc1ccc(-c2cnc(N)cn2)c(F)c1Oc1nccc(N)n1 -US20070082890A1,2,CCOC(=O)Cn1c(C)cccc1=O.NN>>Cc1cccc(=O)n1CC(=O)NN -US20050282880A1,1,COC(=O)c1ccc2[nH]nc(-c3cccc(F)c3)c2c1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)c1ccc2c(c1)c(-c1cccc(F)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US04087524,7,C[C@@H]1CC2=CC(=O)CC[C@]2(CO)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]21>>C[C@@H]1CC2=C[C@H](O)CC[C@]2(CO)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]21 -US20100267775A1,8,Cc1cc(OCCO)c(OCCO)cc1-c1cccc(CO)c1C>>Cc1cc(OCCO)c(OCCO)cc1-c1cccc(C=O)c1C -US07999006B2,1,CC(C)N.O=CCC1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1>>CC(C)NCCC1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US20130029938A1,1,CCCC[C@]1(CC)CS(=O)(=O)c2cc(CBr)c(OC)cc2[C@H](c2ccccc2)N1.CCOP(OCC)OCC>>CCCC[C@]1(CC)CS(=O)(=O)c2cc(CP(=O)(OCC)OCC)c(OC)cc2[C@H](c2ccccc2)N1 -US04029801,1,COc1ccccc1OCCBr.O=C(NC1CCNCC1)c1ccccc1>>COc1ccccc1OCCN1CCC(NC(=O)c2ccccc2)CC1 -US20050222408A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc([N+](=O)[O-])o2)CC1 -US20090062307A1,1,CC(C)(C)OC(=O)CBr.Oc1cccc(Br)c1>>CC(C)(C)OC(=O)COc1cccc(Br)c1 -US08327467B2,3,C=Cc1ccc(C(=O)OC(C)(C)C)c(Nc2ccc(F)cc2)c1.COc1cccc(I)c1>>COc1cccc(/C=C/c2ccc(C(=O)OC(C)(C)C)c(Nc3ccc(F)cc3)c2)c1 -US20060241172A1,9,C[C@]1(CN=[N+]=[N-])COc2cccc(-c3ccccc3Cl)c2O1>>C[C@]1(CN)COc2cccc(-c3ccccc3Cl)c2O1 -US05556853,2,C1COCCN1.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCOCC1 -US05512581,7,O=C(O)C(CC1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1>>OCC(CC1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1 -US06933311B2,2,CCC(C(=O)O)c1cccc2cnccc12.NCc1ccc(SC(F)(F)F)cc1>>CCC(C(=O)NCc1ccc(SC(F)(F)F)cc1)c1cccc2cnccc12 -US20060111353A1,3,Brc1ccc(I)cc1.CC1(C)OB(/C(=C\C2CCCC2)CO)OC1(C)C>>OC/C(=C/C1CCCC1)c1ccc(Br)cc1 -US05149837,6,CCOC(CCn1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)Nc2ccccc2)c1C(C)C)OCC>>CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC=O -US05102877,8,CC(O)C1=CCN(Cc2ccccc2)CC1>>CC(=O)C1=CCN(Cc2ccccc2)CC1 -US20130109662A1,2,CCCCC(=O)CC(=O)OC.CCCCN>>CCCCNC(=O)CC(=O)CCCC -US20090062348A1,6,O=Cc1cc(OCc2ccccc2)ccc1OCc1ccccc1>>O=Cc1cc(OCc2ccccc2)ccc1O -US20030096841A1,2,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C=Nc1ccccc1>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)Nc4ccccc4)c3C2=O)C(=O)N1 -US04505929,1,O=S(=O)(c1ccc(Cl)cc1)C(F)(F)F.Oc1ccc(Cl)c(Cl)c1>>O=S(=O)(c1ccc(Oc2ccc(Cl)c(Cl)c2)cc1)C(F)(F)F -US05629406,1,CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H]1COCc1ccccc1.O=C(O)c1ccccc1>>CC(C)(C)OC(=O)N1CC[C@H](OC(=O)c2ccccc2)[C@H]1COCc1ccccc1 -US07232834B2,6,COC(=O)[C@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1CCC(=O)c1c(F)cnc2ccc(OC)cc12>>COC(=O)[C@H]1CNCC[C@H]1CCC(=O)c1c(F)cnc2ccc(OC)cc12 -US20150126490A1,6,CC(C)(C)OC(=O)Nc1cnc(CCC#N)cn1>>N#CCCc1cnc(N)cn1 -US20070167437A1,2,CCOc1ccsc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.Cc1noc(C)c1C(=O)N1CCNCC1>>CCOc1ccsc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(C(=O)c2c(C)noc2C)CC1 -US07037880B2,9,CC(C)(C)c1ccc(CBr)cc1.[C-]#N>>CC(C)(C)c1ccc(CC#N)cc1 -US20090005436A1,2,CC(C)(C)OC(=O)NN.O=C(O)Cc1cc(=O)oc2cc(O)ccc12>>CC(C)(C)OC(=O)NNC(=O)Cc1cc(=O)oc2cc(O)ccc12 -US20110275630A1,2,Cc1cccc(N=C=S)c1.Nc1ccc(-c2cccc3c2CNC3=O)cc1>>Cc1cccc(NC(=S)Nc2ccc(-c3cccc4c3CNC4=O)cc2)c1 -US08575360B2,6,CC(C)(C)OC(=O)NC1(C(=O)NC2(c3ncc(I)cn3)CC2)CC1>>NC1(C(=O)NC2(c3ncc(I)cn3)CC2)CC1 -US20090247500A1,6,COc1ccc(Cl)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@@H]1CCN1C(=O)OC(C)(C)C>>COc1ccc(Cl)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@H]1CCN1 -US08222248B2,7,Cc1ccc(NC(=O)c2ccc([N+](=O)[O-])c(NCCO)c2)cc1C>>Cc1ccc(NC(=O)c2ccc(N)c(NCCO)c2)cc1C -US20120270865A2,2,CCOC(=O)CCNC.Cc1c(C(Nc2ccc(C(=O)O)nc2)C2CCCCC2)oc2ccc(F)cc12>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(F)cc3c2C)C2CCCCC2)cn1 -US20150164904A1,2,CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)Cl)c1.Nc1ccc(N2CCCCC2)cc1C(=O)Nc1nc(-c2cccc(C(F)(F)F)c2)cs1>>CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2nc(-c3cccc(C(F)(F)F)c3)cs2)c1 -US07696210B2,7,O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(CO)ccc1F -US20080167371A1,2,CS(=O)(=O)Cl.Cc1cc(CN(CCC(C)C)C(=O)OC(C)(C)C)ccc1-c1ccc(N)cc1>>Cc1cc(CN(CCC(C)C)C(=O)OC(C)(C)C)ccc1-c1ccc(NS(C)(=O)=O)cc1 -US20140094462A1,6,C[C@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N1C>>C[C@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)O)C(=O)N1C -US20060079548A1,1,CNC(=O)c1c(C)[nH]c2cc(O)ccc12.O=C(c1cc2nccc(Cl)c2s1)N1CC[C@@H](O)C1>>CNC(=O)c1c(C)[nH]c2cc(Oc3ccnc4cc(C(=O)N5CCC(O)C5)sc34)ccc12 -US20050176775A1,1,COC(=O)c1ccc(F)c(-n2c(C)cc(O)cc2=O)c1.Fc1ccc(CBr)c(F)c1>>COC(=O)c1ccc(F)c(-n2c(C)cc(OCc3ccc(F)cc3F)cc2=O)c1 -US07683079B2,9,CCCCC1CN(CCc2ccccc2)CCC1=O.NO>>CCCCC1CN(CCc2ccccc2)CCC1=NO -US08211919B2,2,O=C=Nc1ccccc1.c1cc(-c2ccc3c(c2)CCN3)ccn1>>O=C(Nc1ccccc1)N1CCc2cc(-c3ccncc3)ccc21 -US08338424B2,1,CC(C)(C)OC(=O)N1CC[C@@H](O)C1.O=C(O)[C@](O)(c1ccccc1)C1CCCC1>>CC(C)(C)OC(=O)N1CC[C@@H](OC(=O)[C@](O)(c2ccccc2)C2CCCC2)C1 -US07547710B2,2,CC(=O)Cl.Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc3ccc(N)cc23)cc1>>CC(=O)Nc1ccc2nc(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c3ccc(C)cc3)c2c1 -US07713994B2,1,O=[N+]([O-])c1ccc(F)cc1.c1c[nH]cn1>>O=[N+]([O-])c1ccc(-n2ccnc2)cc1 -US08349861B2,1,CI.Cc1c2ccc(Nc3ccnc(Cl)n3)cc2nn1C>>Cc1c2ccc(N(C)c3ccnc(Cl)n3)cc2nn1C -US20120101105A1,3,CCOC(=O)/C=C/c1cn(C)c2ccccc12.C[S+](C)(C)=O>>CCOC(=O)[C@@H]1C[C@H]1c1cn(C)c2ccccc12 -US07504420B2,7,C=C(C)c1cccc(C#N)c1>>CC(C)c1cccc(C#N)c1 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3sc(Cl)cc23)cc1Cl.Cc1ncc[nH]1>>COc1ccc(CNc2nc(-n3ccnc3C)nc3sc(Cl)cc23)cc1Cl -US20090281092A1,2,COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(F)(F)C(=O)N2C.CS(=O)(=O)N1CCC(N)CC1>>COc1cc(C(=O)NC2CCN(S(C)(=O)=O)CC2)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(F)(F)C(=O)N2C -US07030128B2,3,Brc1cccc(Br)n1.CCCC[Sn](CCCC)(CCCC)c1ccccn1>>Brc1cccc(-c2ccccn2)n1 -US20080194555A1,6,CC(C)(C)OC(=O)Nc1nc2cc(OS(=O)(=O)c3c(Cl)cccc3Cl)ccc2[nH]1>>Nc1nc2cc(OS(=O)(=O)c3c(Cl)cccc3Cl)ccc2[nH]1 -US20070155805A1,3,CCCCC(=O)c1oc2cc(C(F)(F)F)ccc2c1C.CCOC(=O)CP(=O)(OCC)OCC>>CCCCC(=CC(=O)OCC)c1oc2cc(C(F)(F)F)ccc2c1C -US20100298325A1,1,COCCOc1cccc(N)c1.Fc1ccc(Oc2ccc(Cl)nc2)cc1>>COCCOc1cccc(Nc2ccc(Oc3ccc(F)cc3)cn2)c1 -US07935721B2,9,O=C1Nc2cccc(Br)c2C1(O)c1cc2c(cc1O)OCC2>>O=C1Nc2cccc(Br)c2C1c1cc2c(cc1O)OCC2 -US06225310B1,2,Nc1cc(Cl)sc1S(N)(=O)=O.S=C=NCC1CCCCC1>>Nc1cc(Cl)sc1S(=O)(=O)NC(=S)NCC1CCCCC1 -US04621097,9,CCOC(=O)CN1C[C@@H]2CCC[C@@H]2C1=O.N>>NC(=O)CN1C[C@@H]2CCC[C@@H]2C1=O -US07256198B2,2,Nc1ccc2c(c1)C1(OCCCO1)C1=NCCCN12.O=C(Cl)c1ccccc1>>O=C(Nc1ccc2c(c1)C1(OCCCO1)C1=NCCCN12)c1ccccc1 -US20060074237A1,2,Cc1nc(N)ccc1COCCF.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>Cc1nc(NS(=O)(=O)c2cccc(C(F)(F)F)c2)ccc1COCCF -US20140171404A1,1,CC(C)(C)OC(=O)NCCC=O.O=C(OCc1cc(Cl)cc(Cl)c1)N1CCNCC1>>CC(C)(C)OC(=O)NCCCN1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1 -US20090076268A1,1,Oc1ccccc1-c1cnccc1Cl>>c1ccc2c(c1)oc1ccncc12 -US20080194576A1,1,CCOC(=O)CBr.CCOC(=O)N1CCN(C(=O)[C@H](CCO)NC(=O)c2cc(OC3CCCC3)nc(-c3ccccc3)n2)CC1>>CCOC(=O)COCC[C@H](NC(=O)c1cc(OC2CCCC2)nc(-c2ccccc2)n1)C(=O)N1CCN(C(=O)OCC)CC1 -US06469039B1,2,COC(=O)c1cnc(Cl)c(N)c1.COCC(=O)Cl>>COCC(=O)Nc1cc(C(=O)OC)cnc1Cl -US04048223,7,CSc1ccc2ccc3ccccc3c(=O)c2c1>>CSc1ccc2c(c1)C(O)c1ccccc1C=C2 -US08518969B2,1,CCOC(=O)CC1CCC(=O)CC1.O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CNC1>>CCOC(=O)CC1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 -US20100029641A1,1,BrCc1cccc(CBr)c1.O=S1(=O)Nc2ccccc2N1c1ccccc1F>>O=S1(=O)N(Cc2cccc(CBr)c2)c2ccccc2N1c1ccccc1F -US20090099161A1,3,C=CC(=O)N(C)C.CCc1nc2c(N)nc3cc(Br)ccc3c2n1CC1CCOCC1>>CCc1nc2c(N)nc3cc(/C=C/C(=O)N(C)C)ccc3c2n1CC1CCOCC1 -US20050070527A1,1,CN1CCNCC1.Clc1ccc2nc(Cl)c(Cl)nc2c1>>CN1CCN(c2nc3ccc(Cl)cc3nc2Cl)CC1 -US20070167622A1,3,CC(=O)c1ccccc1B(O)O.O=C(c1csc(Br)n1)N1CCCC2CCCCC21>>CC(=O)c1ccccc1-c1nc(C(=O)N2CCCC3CCCCC32)cs1 -US08778937B2,1,Cc1cccc(CBr)c1C.Cc1nc2c(Br)cc(N3CCOCC3)cc2[nH]1>>Cc1cccc(Cn2c(C)nc3c(Br)cc(N4CCOCC4)cc32)c1C -US03961055,1,CC(C)I.CS(=O)(=O)c1cccc2c1Sc1ccc(O)cc1N2>>CC(C)Oc1ccc2c(c1)Nc1cccc(S(C)(=O)=O)c1S2 -US20100227856A1,6,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCC1CSCCN1C(=O)OC(C)(C)C>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCC1CSCCN1 -US05849757,7,CCOC(=O)c1cn([C@@H]2C[C@@H]2F)c2c(C)c(F)c(F)c([N+](=O)[O-])c2c1=O>>CCOC(=O)c1cn([C@@H]2C[C@@H]2F)c2c(C)c(F)c(F)c(N)c2c1=O -US20140005146A1,6,COC(=O)C(C)(C)C(C)Nc1c(C(N)=O)cnn2cc(-c3ccccc3)cc12>>CC(Nc1c(C(N)=O)cnn2cc(-c3ccccc3)cc12)C(C)(C)C(=O)O -US07612091B2,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(Cl)cc1C(=O)O>>COC=Cc1ccc(Cl)cc1C(=O)O -US08361962B2,7,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1C>>CC1CCN(C(=O)OC(C)(C)C)CC1CO -US04489094,6,CCOC(=O)c1ccc(N(CC)CCCc2ccc(Cl)cc2)cc1>>CCN(CCCc1ccc(Cl)cc1)c1ccc(C(=O)O)cc1 -US08822453B2,2,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CNCCc3cccnc3)ccc21.Cn1cc(CC(=O)O)c2ccccc21>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CN(CCc3cccnc3)C(=O)Cc3cn(C)c4ccccc34)ccc21 -US20100130446A1,4,CS(=O)(=O)c1ccc(C(CC2CCCO2)C(=O)CCC(=O)c2ccccn2)cc1.[NH4+]>>CS(=O)(=O)c1ccc(C(CC2CCCO2)c2ccc(-c3ccccn3)[nH]2)cc1 -US06809097B1,7,Cc1cc(F)c([N+](=O)[O-])cc1OCc1ccccc1>>Cc1cc(F)c(N)cc1OCc1ccccc1 -US05233053,3,O=C(Cl)CCl.c1ccc2c(c1)CCO2>>O=C(CCl)c1ccc2c(c1)CCO2 -US20070249670A1,6,COC(=O)C1(NC(=O)c2sc(-c3ccc(OC)cc3)cc2NC(=O)Nc2c(C)cc(C)cc2C)CCC1>>COc1ccc(-c2cc(NC(=O)Nc3c(C)cc(C)cc3C)c(C(=O)NC3(C(=O)O)CCC3)s2)cc1 -US20110275797A1,2,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1N.O=C(O)c1ccc(-c2ccccc2)nc1>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(-c2ccccc2)nc1 -US08440702B2,3,COC(=O)c1ccc(-c2ccc(OC)c(B3OC(C)(C)C(C)(C)O3)c2)c(C)c1.C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(Cl)ccc1Br>>COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(Cl)cc3CN3C(=O)O[C@H](c4cc(C(F)(F)F)cc(C(F)(F)F)c4)[C@@H]3C)c2)c(C)c1 -US20140155407A1,3,Brc1ccc(Cn2ccnc2)cn1.Nc1cccc(B(O)O)c1>>Nc1cccc(-c2ccc(Cn3ccnc3)cn2)c1 -US20080125465A1,7,O=[N+]([O-])C1(C(O)c2cc(Cl)cc(Cl)c2)CCCCC1>>NC1(C(O)c2cc(Cl)cc(Cl)c2)CCCCC1 -US20120283271A1,2,Nc1ccn(CCCO)n1.O=C(O)[C@H](CC1CCCC1)N1Cc2ccccc2C1=O>>O=C(Nc1ccn(CCCO)n1)[C@H](CC1CCCC1)N1Cc2ccccc2C1=O -US06162927,2,CCCCNc1cccc(CO)c1.O=C(Br)CBr>>CCCCN(C(=O)CBr)c1cccc(CO)c1 -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC.Cc1cccc(C(=O)N=C=S)c1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4cccc(C)c4)c([N+](=O)[O-])c3)c2cc1OC -US20150133457A1,2,C=CC(=O)Cl.COCCOc1c(F)cc(Nc2nc(Oc3cccc(N)c3)c3cc[nH]c3n2)cc1F>>C=CC(=O)Nc1cccc(Oc2nc(Nc3cc(F)c(OCCOC)c(F)c3)nc3[nH]ccc23)c1 -US07034015B2,1,CC1(C)OCC(CO)O1.CCCC[Sn](/C=C/CBr)(CCCC)CCCC>>CCCC[Sn](/C=C/COCC1COC(C)(C)O1)(CCCC)CCCC -US08940771B2,9,CCOC(=O)[C@]12C[C@H]1CCN2.N>>NC(=O)[C@]12C[C@H]1CCN2 -US06204249B1,7,Nc1c([N+](=O)[O-])cc(Cl)c(Cl)c1Cl>>Nc1cc(Cl)c(Cl)c(Cl)c1N -US20090192162A1,3,C#CCN1CCOCC1.CCOC(=O)COc1ccc(Sc2cc(Br)cc(Oc3ccc(C(F)(F)F)cn3)c2)cc1C>>CCOC(=O)COc1ccc(Sc2cc(C#CCN3CCOCC3)cc(Oc3ccc(C(F)(F)F)cn3)c2)cc1C -US20090247590A1,2,CCOC(=O)c1ccc2c(c1)CCC2NCCc1c[nH]c2ccccc12.CS(=O)(=O)Cl>>CCOC(=O)c1ccc2c(c1)CCC2N(CCc1c[nH]c2ccccc12)S(C)(=O)=O -US20120214802A1,2,COC(=O)[C@@H](N)CO.O=C(O)[C@H]1CCCN1C(=O)OCc1ccccc1>>COC(=O)[C@H](CO)NC(=O)[C@H]1CCCN1C(=O)OCc1ccccc1 -US08163754B2,2,N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O.O=C(O)C1CCC1>>O=C(N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O)C1CCC1 -US04536505,1,Brc1cccnc1.CCOC(=O)c1cc2ccccc2[nH]1>>CCOC(=O)c1cc2ccccc2n1-c1cccnc1 -US07390805B2,1,CNC.C[C@@H](Nc1ncnc2[nH]c(-c3cccc(CNC(=O)CCl)c3)cc12)c1ccccc1>>C[C@@H](Nc1ncnc2[nH]c(-c3cccc(CNC(=O)CN(C)C)c3)cc12)c1ccccc1 -US07030252B2,2,C1COCCN1.O=C(Cl)c1ccc2c(c1)COC2=O>>O=C1OCc2cc(C(=O)N3CCOCC3)ccc21 -US08445501B2,2,CCC(=O)Cl.O=C(NC1CCNCC1)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>CCC(=O)N1CCC(NC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)CC1 -US20150005304A1,9,Cc1cc(C(=O)Cl)ccc1OC(C)C>>Cc1cc(C=O)ccc1OC(C)C -US04898862,2,CCOC(=O)COc1ccc(C2=NNC(=O)NC2C)cc1Cl.NN>>CC1NC(=O)NN=C1c1ccc(OCC(=O)NN)c(Cl)c1 -US20140194431A1,6,O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(c4cccc5ccccc45)CCCC3)n2CCN1C1CCOCC1>>O=C1c2c(O)c(=O)nc(CC3(c4cccc5ccccc45)CCCC3)n2CCN1C1CCOCC1 -US05329012,1,CCCI.CCOC(=O)c1nc(S)[nH]c1C(=O)OCC>>CCCSc1nc(C(=O)OCC)c(C(=O)OCC)[nH]1 -US07803822B2,1,O=C(NCCCl)NCCNC(=O)c1nnn(-c2ccc(C(=O)NCC(F)(F)F)cc2)c1CCCCCF>>O=C(NCC(F)(F)F)c1ccc(-n2nnc(C(=O)NCCN3CCNC3=O)c2CCCCCF)cc1 -US05539112,1,C1CCNC1.CN(C)c1ccc(-c2cc(=O)c3c(NCCCCCCBr)c(F)cc(F)c3o2)cc1F>>CN(C)c1ccc(-c2cc(=O)c3c(NCCCCCCN4CCCC4)c(F)cc(F)c3o2)cc1F -US04547524,2,CC(C)=NNC(=O)c1ccc(Cl)cc1.CN=C=O>>CNC(=O)N(N=C(C)C)C(=O)c1ccc(Cl)cc1 -US20100063047A1,1,Cc1csc2ncnc(Cl)c12.NC1Cc2ccccc2C1>>Cc1csc2ncnc(NC3Cc4ccccc4C3)c12 -US08586550B2,6,CC(C)(C)OC(=O)NCC(=O)c1ccsc1>>NCC(=O)c1ccsc1 -US07205326B2,7,O=[N+]([O-])c1ccc(COCCn2ccnn2)cc1>>Nc1ccc(COCCn2ccnn2)cc1 -US20050004207A1,1,CC(C)(C)OC(=O)NCc1cccc(CO)c1.O=C(Nc1cccc2c1C(=O)NC2=O)c1ccc(Cl)s1>>CC(C)(C)OC(=O)NCc1cccc(CN2C(=O)c3cccc(NC(=O)c4ccc(Cl)s4)c3C2=O)c1 -US08399436B2,1,Clc1ccc(OCc2ccccc2)cc1CBr.O=C(Nc1cc[nH]n1)c1c(F)cccc1F>>O=C(Nc1ccn(Cc2cc(OCc3ccccc3)ccc2Cl)n1)c1c(F)cccc1F -US20080269220A1,1,CCOCCCl.COC(=O)c1ccc(OCc2ccccc2)c(-c2ccc(O)cc2)c1>>CCOCCOc1ccc(-c2cc(C(=O)OC)ccc2OCc2ccccc2)cc1 -US05856518,3,CCOC(=O)C1(C=O)CC1.CC[C@H](N)c1ccccc1.[C-]#N>>CCOC(=O)C1(C(C#N)N[C@@H](CC)c2ccccc2)CC1 -US20090076026A1,1,CC(C)(C)[Si](C)(C)OCCCBr.O=C1NCCN1>>CC(C)(C)[Si](C)(C)OCCCN1CCNC1=O -US20130338104A1,9,N.NC(=O)c1ncn2c(=O)n(CCC(=O)O)nnc12>>NC(=O)CCn1nnc2c(C(N)=O)ncn2c1=O -US05256675,2,CC(=O)O.Nc1ccc(Sc2cnc(N)s2)cc1>>CC(=O)Nc1ccc(Sc2cnc(N)s2)cc1 -US04619945,3,CCOC(=O)CP(=O)(OCC)OCC.COc1cc(C)c(C=O)c(C)c1C>>CCOC(=O)C=Cc1c(C)cc(OC)c(C)c1C -US20130267482A1,2,C=CCN(CC(=O)O)NC(=O)N[C@@H](C)c1ccccc1.CCOC(OCC)[C@H](C)N(Cc1cccc2cccnc12)C(=O)[C@@H](N)Cc1ccc(OC(C)(C)C)cc1>>C=CCN(CC(=O)N[C@@H](Cc1ccc(OC(C)(C)C)cc1)C(=O)N(Cc1cccc2cccnc12)[C@@H](C)C(OCC)OCC)NC(=O)N[C@@H](C)c1ccccc1 -US20060046984A1,6,CC[C@@H](C)[C@@]1(NC(C)=O)CCN([C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)[C@H]2C[C@@H](Oc3cccnc3)CN2C(c2ccccc2)c2ccccc2)C1=O>>CC[C@@H](C)[C@@]1(NC(C)=O)CCN([C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)[C@H]2C[C@@H](Oc3cccnc3)CN2)C1=O -US20080188484A1,1,CC(C)N1CCC(O)CC1.CCOC(=O)c1cc2cc(O)c(C)cc2[nH]1>>CCOC(=O)c1cc2cc(OC3CCN(C(C)C)CC3)c(C)cc2[nH]1 -US20110263591A1,2,CN(C)CCN.O=C(O)c1cccc(-c2cccc3cc(C(=O)N[C@@H]4CN5CCC4CC5)oc23)c1>>CN(C)CCNC(=O)c1cccc(-c2cccc3cc(C(=O)N[C@@H]4CN5CCC4CC5)oc23)c1 -US20070072865A1,2,O=C1OC(c2ccccc2)(c2ccccc2)C2CNCCN12.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)N1CCN2C(=O)OC(c3ccccc3)(c3ccccc3)C2C1 -US08178533B2,2,CCCC1CC(=O)N(Cc2cncn2CC(=O)O)C1.NCc1ccccc1>>CCCC1CC(=O)N(Cc2cncn2CC(=O)NCc2ccccc2)C1 -US06281227B1,6,CC(C)(C)OC(=O)n1c(CN2CC[C@H](NS(=O)(=O)c3ccc(-c4ccc(Cl)s4)s3)C2=O)cc2cnccc21>>O=C1[C@@H](NS(=O)(=O)c2ccc(-c3ccc(Cl)s3)s2)CCN1Cc1cc2cnccc2[nH]1 -US05872117,7,O=C(CBr)c1ccc2sccc2c1>>O[C@@H](CBr)c1ccc2sccc2c1 -US09051305B2,3,Cc1ccc(B(O)O)o1.O=C(Nc1cccnc1)c1cc(Cl)nc2ccc(-c3ccccc3)cc12>>Cc1ccc(-c2cc(C(=O)Nc3cccnc3)c3cc(-c4ccccc4)ccc3n2)o1 -US20090029994A1,6,CCOC(=O)C1CCN(c2cnc(N(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)Cc3cc(C(F)(F)F)ccc3N(CC)CCOC)nc2)CC1>>CCN(CCOC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(N2CCC(C(=O)O)CC2)cn1 -US20150183799A1,6,COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc(N(C)CCNC(=O)OC(C)(C)C)cc1>>COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc(N(C)CCN)cc1 -US04791124,2,Cc1ccc(C(=O)CN)s1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ccc(C(=O)CNC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)s1 -US06809199B2,6,COC(=O)c1ccc(C)c(N2C(=O)CCc3c(-c4ccccc4Cl)cc(OC)cc32)c1>>COC(=O)c1ccc(C)c(N2C(=O)CCc3c(-c4ccccc4Cl)cc(O)cc32)c1 -US06063928,8,OCC1(c2cc(F)cc(OCc3ccccc3)c2)CCOCC1>>O=CC1(c2cc(F)cc(OCc3ccccc3)c2)CCOCC1 -US06545161B2,7,O=c1cc(C(F)(F)F)cnn1-c1c(F)cc(Cl)c(O)c1[N+](=O)[O-]>>Nc1c(O)c(Cl)cc(F)c1-n1ncc(C(F)(F)F)cc1=O -US20110144081A1,2,CN(C(=O)Oc1ccc(F)cc1)[C@@H]1CNC[C@H]1c1ccc(Cl)cc1.O=C(O)C1CCCOC1>>CN(C(=O)Oc1ccc(F)cc1)[C@@H]1CN(C(=O)C2CCCOC2)C[C@H]1c1ccc(Cl)cc1 -US20010051631A1,3,C=O.O=C(NCCCCNCc1cccc2nccn12)C(F)(F)C(F)(F)F>>O=C(NCCCCN1Cc2cccc3ncc(n23)C1)C(F)(F)C(F)(F)F -US06514964B1,7,O=C(Cc1ccccc1Br)NCc1ccccc1>>Brc1ccccc1CCNCc1ccccc1 -US20130165440A1,1,CC(=NN)c1ccc(Br)cc1F>>Cc1n[nH]c2cc(Br)ccc12 -US20110178053A1,1,Nc1cnc(N)c(-c2cc(-c3cccnc3)ncc2Cl)c1>>Nc1cnc2[nH]c3cnc(-c4cccnc4)cc3c2c1 -US20090264405A1,1,CC(OCCN)(C(F)(F)F)C(F)(F)F.N#Cc1ccc2oc(-c3ccc(Br)cc3)nc2c1>>CC(OCCNc1ccc(-c2nc3cc(C#N)ccc3o2)cc1)(C(F)(F)F)C(F)(F)F -US08497281B2,2,Fc1cccc2c1[C@H]1CCCN[C@H]1CC2.O=C(O)c1ccc2[nH]cnc2c1>>O=C(c1ccc2[nH]cnc2c1)N1CCC[C@@H]2c3c(F)cccc3CC[C@@H]21 -US20070060754A1,2,CC(C)N=C=O.CCOCc1nc2c(N)nc3cc(OCCN)ccc3c2n1CC(C)(C)O>>CCOCc1nc2c(N)nc3cc(OCCNC(=O)NC(C)C)ccc3c2n1CC(C)(C)O -US20130131052A1,1,CC1(C)CC(O)CC(C)(C)N1O.O=C(O)C1CC1>>CC1(C)CC(OC(=O)C2CC2)CC(C)(C)N1O -US07625948B2,9,COC(=O)C(C(=O)OC(C)(C)C)c1ccc([N+](=O)[O-])c(C(=O)N(C)C)c1>>COC(=O)Cc1ccc([N+](=O)[O-])c(C(=O)N(C)C)c1 -US08461336B2,1,N#Cc1ccc(F)cc1.Oc1ccc(Br)cc1>>N#Cc1ccc(Oc2ccc(Br)cc2)cc1 -US20090023930A1,2,O=C(O)/C=C(\c1cc(F)cc(F)c1)C(F)(F)F.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(/C=C(\c1cc(F)cc(F)c1)C(F)(F)F)N1C(=O)OC[C@@H]1Cc1ccccc1 -US08461348B2,2,CCOC(=O)c1cnn(Cc2nc(-c3cccc(N)c3)cs2)c1.COCC(=O)Cl>>CCOC(=O)c1cnn(Cc2nc(-c3cccc(NC(=O)COC)c3)cs2)c1 -US05789562,1,CN(C)C=O.Nc1nc2c(nnn2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1>>CN(C)C=Nc1nc2c(nnn2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1 -US20080200448A1,1,CCOC(=O)CCCc1nc(Cl)c(C#N)cc1C(=O)OCC.O=C(NS(=O)(=O)Cc1ccccc1)C1CCNCC1>>CCOC(=O)CCCc1nc(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)c(C#N)cc1C(=O)OCC -US20080081907A1,2,Cc1ccc(CNc2ccc3c(N)cccc3n2)o1.O=S(=O)(Cl)c1ccccc1>>Cc1ccc(CNc2ccc3c(NS(=O)(=O)c4ccccc4)cccc3n2)o1 -US09040032B2,1,CC(C)(C)OC(=O)NCCNCc1ccccc1.CI>>CN(CCNC(=O)OC(C)(C)C)Cc1ccccc1 -US06069149,6,COC(=O)c1ccc(C(OCCN(C)C)c2ccccc2)cc1>>CN(C)CCOC(c1ccccc1)c1ccc(C(=O)O)cc1 -US20080269170A1,2,CS(=O)(=O)CCN1CCC(N)CC1.O=S(=O)(Cl)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1>>CS(=O)(=O)CCN1CCC(NS(=O)(=O)c2ccc(Nc3nccc(Nc4ccc(F)cc4)n3)cc2)CC1 -US20100063067A1,6,COc1cc(N2CCC(C(=O)OC(C)(C)C)CC2)ccc1Cl>>COc1cc(N2CCC(C(=O)O)CC2)ccc1Cl -US20140155391A1,2,COC(=O)c1ccc(CN2CCOCC2)c(O)c1.CS(=O)(=O)Cl>>COC(=O)c1ccc(CN2CCOCC2)c(OS(C)(=O)=O)c1 -US20050009845A1,1,CCCN.CS(=O)(=O)OCC#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1>>CCCNCC#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 -US20130237555A1,7,O=Cc1cnccc1-c1ccc(Cl)cc1F>>OCc1cnccc1-c1ccc(Cl)cc1F -US05646171,7,CCCCc1nc(C(C)=O)c(C#N)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc(C(C)O)c(C#N)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1 -US07772227B2,7,c1ccc2nc(C3CCCC3)ccc2c1>>c1ccc2c(c1)CCC(C1CCCC1)N2 -US08569535B2,6,CCOC(=O)C1(NC(=O)c2cccc(C)c2C=CC2CC2)Cc2ccccc2C1>>Cc1cccc(C(=O)NC2(C(=O)O)Cc3ccccc3C2)c1C=CC1CC1 -US20050171131A1,1,Nc1ccc(-c2c(N)nc(N)nc2CO)cc1.O=Cc1ccc(Cl)cc1>>Nc1nc(N)c(-c2ccc(NCc3ccc(Cl)cc3)cc2)c(CO)n1 -US20090192096A1,2,CC(C)CCN.O=C(O)c1ccccc1-c1ccccc1CN1C(=O)c2ccccc2C1=O>>CC(C)CCNC(=O)c1ccccc1-c1ccccc1CN1C(=O)c2ccccc2C1=O -US20050256180A1,2,NC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CCc1ccc(N)cc1-2.O=C(O)c1cc(Cl)ncc1Cl>>NC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CCc1ccc(NC(=O)c3cc(Cl)ncc3Cl)cc1-2 -US20140057896A1,1,CN(C)CCCl.O=[N+]([O-])c1ccc(O)cn1>>CN(C)CCOc1ccc([N+](=O)[O-])nc1 -US20080249093A1,9,COC(=O)c1ccc(OC(C)C)c(Br)c1.[C-]#N>>COC(=O)c1ccc(OC(C)C)c(C#N)c1 -US20100069339A1,6,CC(C)(O)CCCC(C)(CCO[Si](C)(C)C(C)(C)C)C1CCC2C(O[Si](C)(C)C(C)(C)C)CCCC21C>>CC(C)(O)CCCC(C)(CCO)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@@]21C -US07060844B2,2,Nc1ccc2c(c1)COC2=O.O=C(CCl)OC(=O)CCl>>O=C(CCl)Nc1ccc2c(c1)COC2=O -US08486939B2,1,COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)nc(N2CCOCC2)n1.Nc1cccnc1>>COc1cccc2c1nc(C(F)F)n2-c1nc(Nc2cccnc2)nc(N2CCOCC2)n1 -US20090264446A9,2,CC(=O)Cl.CSc1nccc(-c2cc(N)c(Cl)nc2-c2ccc(F)cc2)n1>>CSc1nccc(-c2cc(NC(C)=O)c(Cl)nc2-c2ccc(F)cc2)n1 -US07592363B2,7,O=C1CCCc2c(Oc3ccc(-c4c5cccc(C(F)(F)F)c5nn4Cc4ccc(Cl)cc4F)cc3)cccc21>>OC1CCCc2c(Oc3ccc(-c4c5cccc(C(F)(F)F)c5nn4Cc4ccc(Cl)cc4F)cc3)cccc21 -US20050112066A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.OCCNCCO>>OCCN(CCO)C(c1ccccc1)(c1ccccc1)c1ccccc1 -US06897306B2,2,CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1.CN>>CNC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1 -US20050209223A1,3,COC(=S)NCc1cn(-c2ccc(N3CCC(=O)CC3)c(F)c2)nn1.N#CCC#N>>COC(=S)NCc1cn(-c2ccc(N3CCC(=C(C#N)C#N)CC3)c(F)c2)nn1 -US20090023733A1,1,CC(C)(C)OC(=O)c1ccc(F)c(Cl)c1.COC(=O)CS>>COC(=O)CSc1ccc(C(=O)OC(C)(C)C)cc1Cl -US20090264650A1,2,CCOC(=O)CN=C=O.Nc1ccc(CC2CCN(C3CCCCC3)C2=O)c(Cl)c1>>CCOC(=O)CNC(=O)Nc1ccc(CC2CCN(C3CCCCC3)C2=O)c(Cl)c1 -US07446222B2,1,CC(C)CBr.CCOC(=O)c1ccccc1-c1ccccc1-c1cc(Cl)ccc1O>>CCOC(=O)c1ccccc1-c1ccccc1-c1cc(Cl)ccc1OCC(C)C -US20060167052A1,1,COc1ccc(OC)c(CO)c1.FC(F)(F)c1cc(CO[C@H]2CCNC[C@H]2c2ccccc2)cc(C(F)(F)F)c1>>COc1ccc(OC)c(CN2CC[C@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](c3ccccc3)C2)c1 -US07435735B2,2,COc1c2n(c3c(NC(=O)OC(C)(C)C)cn(Cc4ccc(F)c(Cl)c4)c(=O)c13)CCN(C)C2=O.CS(=O)(=O)Cl>>COc1c2n(c3c(N(C(=O)OC(C)(C)C)S(C)(=O)=O)cn(Cc4ccc(F)c(Cl)c4)c(=O)c13)CCN(C)C2=O -US06147110,3,COc1ccc2c(c1)C(=O)CO2.O=Cc1ccccc1>>COc1ccc2c(c1)C(=O)C(=Cc1ccccc1)O2 -US20040192653A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1ncc2cc(Oc3ccc(F)cc3CN)ccc21>>Cn1ncc2cc(Oc3ccc(F)cc3CNC(=O)OC(C)(C)C)ccc21 -US07425554B2,1,CCCCC=O.COc1ccc(C2=CCC(C)(C)CC2)c(N2CCNCC2)c1>>CCCCCN1CCN(c2cc(OC)ccc2C2=CCC(C)(C)CC2)CC1 -US06063926,8,CSc1ccccc1C1CCN(C(=O)OCc2ccccc2)CC1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccccc1C1CCN(C(=O)OCc2ccccc2)CC1 -US20150239900A1,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1ccccc1-c1c[nH]c2ncnc(Cl)c12>>CC(C)(C)OC(=O)N1CCN(c2ncnc3[nH]cc(-c4ccccc4Cl)c23)CC1 -US08546395B2,1,C[C@@H]1CNCCN1.Cc1ccc(S(=O)(=O)n2ccc3c(-c4c(-c5ccc(F)cc5)nc5ccc(Cl)nn45)ccnc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(-c4c(-c5ccc(F)cc5)nc5ccc(N6CCN[C@H](C)C6)nn45)ccnc32)cc1 -US05391566,1,CCCc1cc(CO)cc(Cl)c1O.COC(=O)C(Br)c1ccc2c(c1)OCO2>>CCCc1cc(CO)cc(Cl)c1OC(C(=O)OC)c1ccc2c(c1)OCO2 -US20100069381A1,1,ClCC1CC1.Sc1nnc(-c2ccc3c(c2)CCO3)o1>>c1cc2c(cc1-c1nnc(SCC3CC3)o1)CCO2 -US05117057,2,CC(C)(C)NN.O=C(Cl)c1ccccc1>>CC(C)(C)NNC(=O)c1ccccc1 -US08273773B2,7,COc1cc(C(=O)O)ccc1C(C)(C)C>>COc1cc(CO)ccc1C(C)(C)C -US07659279B2,2,COc1cc(OC[C@H]2C[C@H](O)CN2)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1.O=C(O)CO>>COc1cc(OC[C@H]2C[C@H](O)CN2C(=O)CO)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1 -US20040082559A1,1,COC(=O)CC1Cc2ccc(O)cc2CN(C)C1=O.O=C(NCCCO)OCc1ccc([N+](=O)[O-])cc1>>COC(=O)CC1Cc2ccc(OCCCNC(=O)OCc3ccc([N+](=O)[O-])cc3)cc2CN(C)C1=O -US20130196974A1,6,COc1ccc2c(c1)CN(c1cc(NCC3(N)COC3)c3cc(C)ccc3n1)CCS2(=O)=O>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccc(O)cc4C3)cc(NCC3(N)COC3)c2c1 -US04581452,2,O=C(NCc1ccccc1)NCC(C(=O)O)C(F)(F)F>>O=C1NCC(C(F)(F)F)C(=O)N1Cc1ccccc1 -US04678793,8,C/C(=C\c1ccc(CO)cc1)c1ccc2c(c1)C(C)(C)CCO2>>C/C(=C\c1ccc(C=O)cc1)c1ccc2c(c1)C(C)(C)CCO2 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.NCC(F)(F)C(F)(F)F>>CC#CCOc1cc(NCC(F)(F)C(F)(F)F)ncn1 -US20140213578A1,2,NC1CCCC(=C2c3ccccc3CCc3ccccc32)C1.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>O=S(=O)(NC1CCCC(=C2c3ccccc3CCc3ccccc32)C1)c1ccc(OC(F)(F)F)cc1 -US04009181,6,O=C(O)C1CCc2c(n(C(=O)c3ccccc3)c3ccc(Cl)cc23)C1>>O=C(O)C1CCc2c([nH]c3ccc(Cl)cc23)C1 -US20050245588A1,1,C[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CC[C@H]1C2=CC[C@@H](C(F)(F)F)[C@@H]1N.O=Cc1ccccc1>>C[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CC[C@H]1C2=CC[C@@H](C(F)(F)F)[C@@H]1NCc1ccccc1 -US20090181963A1,6,CC(C)(C)OC(=O)Cn1nnc2c(N3CCOCC3)nc(-c3cccc(CO)c3)nc21>>O=C(O)Cn1nnc2c(N3CCOCC3)nc(-c3cccc(CO)c3)nc21 -US20140148474A1,3,Brc1cncs1.Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(B2OC(C)(C)C(C)(C)O2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cncs2)c1 -US20120157436A1,3,O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(Br)nnc2C1.OB(O)c1ccccc1>>O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(nnc2-c2ccccc2)C1 -US20100280268A1,1,COC(=O)c1cc(O)ccc1NS(=O)(=O)c1ccc(C)cc1.O=[N+]([O-])c1ccc(F)cc1NCc1ccccc1>>COC(=O)c1cc(Oc2ccc([N+](=O)[O-])c(NCc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1 -US20100069352A1,4,CCOC(=O)CC(=O)CCl.NC(=S)c1ccc(Cl)cc1>>CCOC(=O)Cc1csc(-c2ccc(Cl)cc2)n1 -US05296484,1,CC(O)c1ccc(C(C)(C)C)cc1.Clc1ncnc2ccccc12>>CC(Oc1ncnc2ccccc12)c1ccc(C(C)(C)C)cc1 -US05059602,9,NO.Nc1ccncc1C(=O)C1CCCCC1>>Nc1ccncc1C(=NO)C1CCCCC1 -US06858638B2,7,Cc1cc2[nH]nc(-c3ccccc3)c2cc1[N+](=O)[O-]>>Cc1cc2[nH]nc(-c3ccccc3)c2cc1N -US20100137372A1,2,CCCC(=O)O.Cc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1N>>CCCC(=O)Nc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C -US20130018039A1,6,COCCn1c(-c2c[nH]c(-c3ccc4scnc4c3)n2)nc2cc(C(=O)OC)ccc21>>COCCn1c(-c2c[nH]c(-c3ccc4scnc4c3)n2)nc2cc(C(=O)O)ccc21 -US05268375,3,Cc1ccc(I)cc1.O=[N+]([O-])c1ccccc1Br>>Cc1ccc(-c2ccccc2[N+](=O)[O-])cc1 -US06071945,6,COc1ccc(-c2csc3c2-n2cccc2C3=O)cc1OC>>COc1ccc(-c2csc3c2-n2cccc2C3=O)cc1O -US20140336177A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1c([C@@H]2CN3CCNC[C@H]3CO2)cc(I)c(F)c1C#N>>Cc1c([C@@H]2CN3CCN(C(=O)OC(C)(C)C)C[C@H]3CO2)cc(I)c(F)c1C#N -US20060257987A1,9,CCCc1c(O)ccc(C(=O)c2ccccc2)c1O.NO>>CCCc1c(O)ccc(C(=NO)c2ccccc2)c1O -US20100190980A1,2,Cn1ccc(N)n1.O=C(O)c1nc(Br)cnc1Sc1ccc(F)cc1>>Cn1ccc(NC(=O)c2nc(Br)cnc2Sc2ccc(F)cc2)n1 -US06960578B2,2,CC(C)(C)OC(=O)CC(=O)c1ccnc(C#N)c1.CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2F)cc1N>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2F)cc1NC(=O)CC(=O)c1ccnc(C#N)c1 -US20080058356A1,2,COc1cccc(CC(=O)Cl)c1.Nc1cc(-n2cccn2)nc(-c2ccco2)n1>>COc1cccc(CC(=O)Nc2cc(-n3cccn3)nc(-c3ccco3)n2)c1 -US04005217,2,CCOC(=O)N=C=S.CN(C)CC(=O)Nc1ccccc1N>>CCOC(=O)NC(=S)Nc1ccccc1NC(=O)CN(C)C -US05210193,1,C#CC1CNCCN1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)cc21>>C#CC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3CC)CCN1 -US04725615,1,NNc1ccc(Br)cc1.O=C1CCCC(=O)C1>>O=C1CCCC(=NNc2ccc(Br)cc2)C1 -US04233216,7,CC(=O)CO[C@@H]1[C@@H](NC(=O)Cc2ccccc2)C(=O)N1C(=O)C(=O)OC(c1ccccc1)c1ccccc1>>CC(=O)CO[C@@H]1[C@@H](NC(=O)Cc2ccccc2)C(=O)N1C(O)C(=O)OC(c1ccccc1)c1ccccc1 -US20120101078A1,2,Nc1ccc(-c2cc(F)cc(F)c2)cn1.O=C(O)[C@H]1CC[C@@H](N2CCCC2=O)CC1>>O=C(Nc1ccc(-c2cc(F)cc(F)c2)cn1)[C@H]1CC[C@@H](N2CCCC2=O)CC1 -US20020137776A1,1,CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-].C[S-]>>CSc1ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c1 -US20040006065A1,2,CC(C)(C)OC(=O)NC(=N)c1ccc(CN)cc1.O=C(Nc1cnc2n(c1=O)C(Cc1ccccc1)(C(=O)O)CC2)OCc1ccccc1>>CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)C2(Cc3ccccc3)CCc3ncc(NC(=O)OCc4ccccc4)c(=O)n32)cc1 -US06297375B1,2,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CNc1cnccc1-c1ccccc1Cl>>CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1-c1ccccc1Cl -US05760032,2,CCOC(=O)Cn1c(C(=O)O)cc2ccccc21.CCc1cc2c(s1)-n1c(CN)nnc1CN=C2c1ccccc1Cl>>CCOC(=O)Cn1c(C(=O)NCc2nnc3n2-c2sc(CC)cc2C(c2ccccc2Cl)=NC3)cc2ccccc21 -US08778939B2,2,CN(C)C(=O)c1ccc(OCc2ccccc2)c(C(=O)O)c1.Nc1cccnc1>>CN(C)C(=O)c1ccc(OCc2ccccc2)c(C(=O)Nc2cccnc2)c1 -US20100004292A1,1,Cn1cc(C(=O)Nc2ccc(NCCO[Si](C)(C)C(C)(C)C)cc2)c(NC(=O)c2ccc(Cl)s2)n1.N#CBr>>Cn1cc(C(=O)Nc2ccc(N(C#N)CCO[Si](C)(C)C(C)(C)C)cc2)c(NC(=O)c2ccc(Cl)s2)n1 -US08518972B2,1,CCNCCOc1ccccc1.O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1>>CCN(CCOc1ccccc1)Cc1ccc(COc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1 -US20110178062A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1c[nH]c2c(C(=O)O)cccc12>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc3c(C=O)c[nH]c23)CC1 -US06933305B2,2,COC(=O)c1ccc2c(c1)SCCC2N.O=C(Cl)OCc1ccccc1>>COC(=O)c1ccc2c(c1)SCCC2NC(=O)OCc1ccccc1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCN(C)CC1.Oc1ccc2cccnc2c1>>COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1OCCCN1CCN(C)CC1 -US07202269B2,2,Cc1ccc(C(CC(=O)O)NC(=O)Nc2ccc(-c3ccccc3)cc2)cc1.NCCN1CCCC1>>Cc1ccc([C@@H](CC(=O)NCCN2CCCC2)NC(=O)Nc2ccc(-c3ccccc3)cc2)cc1 -US07943612B2,6,COC(=O)COc1ccc(OCC#Cc2cc(C#CCN3CCCCC3)cc(C#Cc3ccc(C(F)(F)F)cc3)c2)cc1C>>Cc1cc(OCC#Cc2cc(C#CCN3CCCCC3)cc(C#Cc3ccc(C(F)(F)F)cc3)c2)ccc1OCC(=O)O -US05079243,5,CN1CCc2cc(Cl)c(O)cc2C(c2cccc3ccoc23)C1.COCCl>>COCOc1cc2c(cc1Cl)CCN(C)CC2c1cccc2ccoc12 -US20080221157A1,1,CC(=O)CCCCC[C@H]([NH3+])C(=O)NCCc1c(-c2ccccc2)[nH]c2ccccc12.O=CCc1c[nH]c2ccccc12>>CC(=O)CCCCC[C@H](NCCc1c[nH]c2ccccc12)C(=O)NCCc1c(-c2ccccc2)[nH]c2ccccc12 -US05110815,1,Cn1c2c(ccc1=O)C(=O)CCC2.NCCc1ccc(Cl)cc1>>Cn1c2c(ccc1=O)C(NCCc1ccc(Cl)cc1)CCC2 -US20130190330A1,1,Clc1ccccc1-c1ncc(CBr)o1.O=c1[nH]nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F>>O=c1n(Cc2cnc(-c3ccccc3Cl)o2)nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F -US20140350011A1,2,CCN=C=O.NC(=O)[C@@H]1[C@H](Nc2c(Cl)cnc3[nH]c(-c4cnn(C5CCNCC5)c4)nc23)[C@H]2C=C[C@@H]1C2>>CCNC(=O)N1CCC(n2cc(-c3nc4c(N[C@@H]5[C@H]6C=C[C@H](C6)[C@@H]5C(N)=O)c(Cl)cnc4[nH]3)cn2)CC1 -US08202881B2,6,CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(=S)NC(=O)c3ccccc3)nc21>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(N)=S)nc21 -US06964961B2,2,NCCc1ccccn1.O=C([O-])c1cc2nccc(Cl)c2s1>>O=C(NCCc1ccccn1)c1cc2nccc(Cl)c2s1 -US05622954,3,BrC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.CC(C)(C=O)c1ccc(C(F)(F)F)cc1>>CC(C)(/C=C/Br)c1ccc(C(F)(F)F)cc1 -US20100331293A1,1,Cc1c(N2CCC2=O)nc2cc(F)cc(F)c2c1Cl.Nc1cncc(N2CCOCC2)c1>>Cc1c(N2CCC2=O)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1 -US20070203210A1,1,COc1cc2nc[nH]c2cc1OC.N#Cc1sc(Cl)nc1-c1ccccc1>>COc1cc2ncn(-c3nc(-c4ccccc4)c(C#N)s3)c2cc1OC -US04456761,6,CC(=O)SCCCC(=O)N1CC(O)(c2ccc(C)cc2)C[C@H]1C(=O)O>>Cc1ccc(C2(O)C[C@@H](C(=O)O)N(C(=O)CCCS)C2)cc1 -US20090264401A1,6,CCOC(=O)c1cnc(C)nc1C(C)(C)C>>Cc1ncc(C(=O)O)c(C(C)(C)C)n1 -US20120214784A1,1,Cc1ccccc1I.Cc1n[nH]cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12>>Cc1ccccc1-n1cc(CN2CCC3(CC2)OCC(F)(F)c2cc(Cl)sc23)c(C)n1 -US08946235B2,1,CNCCN(C)C.COc1cc(F)c([N+](=O)[O-])cc1Nc1nccc(-c2cnn3ccccc23)n1>>COc1cc(N(C)CCN(C)C)c([N+](=O)[O-])cc1Nc1nccc(-c2cnn3ccccc23)n1 -US08153647B2,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COCCCOc1cc(C=O)ccc1O>>CCOC(=O)C=Cc1ccc(O)c(OCCCOC)c1 -US05049551,6,CC(C)(C)OC(=O)NCCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O>>NCCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O -US20090299066A1,6,COc1ncc(C#CC2=CCN(C(=O)OC(C)(C)C)CC2)cn1>>COc1ncc(C#CC2=CCNCC2)cn1 -US08680108B2,1,COC(=O)N[C@H]1CCN(c2c(C(C)=O)cc(Cl)c3cccnc23)C1.[NH4+]>>COC(=O)N[C@H]1CCN(c2c(C(C)N)cc(Cl)c3cccnc23)C1 -US20100016287A1,7,CC(=O)N1CCc2ccc([N+](=O)[O-])cc2CC1>>CC(=O)N1CCc2ccc(N)cc2CC1 -US20090227603A1,1,CCC[S-].COc1cc(Br)cc(Br)c1>>CCCSc1cc(Br)cc(OC)c1 -US20040225009A1,6,COc1ccc(CN2C(=O)[C@@H](OCc3ccccc3)[C@H]2C(C)(C)C)cc1>>CC(C)(C)[C@H]1NC(=O)[C@H]1OCc1ccccc1 -US20080255124A1,1,Brc1ccc(Br)nc1.COc1ccc(CO)cc1>>COc1ccc(COc2ccc(Br)cn2)cc1 -US20100216810A1,2,N#CC1(c2cccc(C(=O)O)c2)CC1.N#Cc1c(Oc2ccc(F)c(N)c2)ccc2nc(NC(=O)C3CC3)sc12>>N#Cc1c(Oc2ccc(F)c(NC(=O)c3cccc(C4(C#N)CC4)c3)c2)ccc2nc(NC(=O)C3CC3)sc12 -US20110046170A1,6,CCOC(=O)c1cc(C)cc(CC(C)C)n1>>Cc1cc(CC(C)C)nc(C(=O)O)c1 -US20050165050A1,10,Cc1ccc2c([N+](=O)[O-])cccc2n1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1cccc2nc(CBr)ccc12 -US20020032207A1,10,C(=C1CCC(Cc2ccccc2)CC1)c1nc2ccccc2[nH]1.O>>OC(c1nc2ccccc2[nH]1)C1CCC(Cc2ccccc2)CC1 -US08293734B2,1,C=C(C)CCl.Oc1ccc(OCc2ccccc2)cc1>>C=C(C)COc1ccc(OCc2ccccc2)cc1 -US08163728B2,2,COC(=O)c1cc(OCc2c(-c3ccc(Cl)cc3)noc2CO)nn1C.NC1CC1>>Cn1nc(OCc2c(-c3ccc(Cl)cc3)noc2CO)cc1C(=O)NC1CC1 -US07105671B2,9,Cc1ccc(NC(=O)[C@H](CC2CCC(=O)CC2)c2ccc(S(C)(=O)=O)c(Cl)c2)nc1.NO>>Cc1ccc(NC(=O)[C@H](CC2CCC(=NO)CC2)c2ccc(S(C)(=O)=O)c(Cl)c2)nc1 -US06498185B1,7,CC(C)(C)OC(=O)N1CCN(c2cc(Cl)cc(C(=O)Nc3ccc(Cl)cn3)c2[N+](=O)[O-])CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(Cl)cc(C(=O)Nc3ccc(Cl)cn3)c2N)CC1 -US20050222207A1,6,COc1cc(N(Cc2cncs2)c2ccc(C(=O)OC(C)(C)C)cc2)ccc1C(N)=O>>COc1cc(N(Cc2cncs2)c2ccc(C(=O)O)cc2)ccc1C(N)=O -US20130345181A1,1,COc1ccc(N)cc1OC.Cn1c(-c2cnn(C(=O)OC(C)(C)C)c2)cc2cnc(Br)cc21>>COc1ccc(Nc2cc3c(cn2)cc(-c2cnn(C(=O)OC(C)(C)C)c2)n3C)cc1OC -US20020037907A1,6,COC(OC)C1CCN(c2ccc(C(=O)N[C@@H](CC(=O)OCc3ccccc3)C(=O)OCc3ccccc3)cc2)CC1>>O=CC1CCN(c2ccc(C(=O)N[C@@H](CC(=O)OCc3ccccc3)C(=O)OCc3ccccc3)cc2)CC1 -US20150126492A1,9,COc1cc(C(=O)O)c([N+](=O)[O-])c(F)c1OC.N>>COc1cc(C(N)=O)c([N+](=O)[O-])c(F)c1OC -US08426429B2,3,CC1(C)OB(c2ccc([N+](=O)[O-])c(C=O)c2)OC1(C)C.O=S(=O)(NCCc1ccccc1Br)c1ccccc1>>O=Cc1cc(-c2ccccc2CCNS(=O)(=O)c2ccccc2)ccc1[N+](=O)[O-] -US20150152108A1,3,Cc1cc(B(O)O)ccn1.O=C(Nc1ncnc2[nH]nnc12)N1c2nc(Cl)ccc2N2CC[C@H]1C2>>Cc1cc(-c2ccc3c(n2)N(C(=O)Nc2ncnc4[nH]nnc24)[C@H]2CCN3C2)ccn1 -US20140194620A1,1,Cn1n[n+](CCl)cc1-c1ccccc1.Oc1ccc2ccccc2c1>>Cn1n[n+](COc2ccc3ccccc3c2)cc1-c1ccccc1 -US05470851,7,N#CCCCCN1CCC(=C(c2ccccc2)c2ccccc2)CC1>>NCCCCCN1CCC(=C(c2ccccc2)c2ccccc2)CC1 -US20150025070A1,6,COC(=O)CN1CCC(c2nnc(-c3ccc(F)cc3)o2)CC1>>O=C(O)CN1CCC(c2nnc(-c3ccc(F)cc3)o2)CC1 -US20070287707A1,3,COCCOc1cc2c(Br)cnnc2cc1OC.OB(O)c1cccc(Br)c1>>COCCOc1cc2c(-c3cccc(Br)c3)cnnc2cc1OC -US20140179690A1,9,C=C[C@@H](CF)OCC(=O)c1ccccc1F.NO>>C=C[C@@H](CF)OCC(=NO)c1ccccc1F -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](c2ccccc2)NC1=O.O=C(O)[C@@H]1C[C@H]1c1ccc(Cl)cc1>>CC(C)C[C@H]1C(=O)N[C@@H](c2ccccc2)CN1C(=O)[C@@H]1C[C@H]1c1ccc(Cl)cc1 -US06469028B1,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(C)cc2)=CCC3(C)C)cc1>>Cc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 -US04945098,1,C=C(CO)COCCCCCCCCCCCCCCCC.CS(=O)(=O)OCCCCCOS(C)(=O)=O>>C=C(COCCCCCCCCCCCCCCCC)COCCCCCOS(C)(=O)=O -US20100003216A1,6,C=CC1CC1(NC(=O)C1CC(Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)NC(C(=O)NC1c2ccccc2CC1O)C(C)(C)C)C(=O)OCC>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)N[C@H](C(=O)N[C@H]1c2ccccc2C[C@H]1O)C(C)(C)C)C(=O)O -US20110118238A1,7,CCOc1cc(N2CCC(N(C)C)CC2)ccc1[N+](=O)[O-]>>CCOc1cc(N2CCC(N(C)C)CC2)ccc1N -US06022895,3,C=CCNC.C=O.O=C1CCCCc2ccccc21>>C=CCN(C)CC1CCCc2ccccc2C1=O -US20130289033A1,3,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(I)cc1.OB(O)c1ccccc1Cl>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(-c2ccccc2Cl)cc1 -US04705797,1,BrCCCCBr.COC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc([N+](=O)[O-])c1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCBr)C1c1cccc([N+](=O)[O-])c1 -US08324216B2,2,COC[C@H]1CN(c2ccc(Cl)c(OC)c2)CCN1.Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O>>COC[C@H]1CN(c2ccc(Cl)c(OC)c2)CCN1C(=O)Cn1nc(C(F)(F)F)c(Cl)c1C -US09156840B2,7,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccccc4)CC3)C2=O)c1>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(O)c4ccccc4)CC3)C2=O)c1 -US20060069116A1,4,CNc1ccncc1N.O=C(O)C(F)(F)F>>Cn1c(C(F)(F)F)nc2cnccc21 -US05917048,5,CC(C)(C)c1cc(Br)c(O)c(C(C)(C)C)c1.COCCl>>COCOc1c(Br)cc(C(C)(C)C)cc1C(C)(C)C -US20060019973A1,6,CCOC(=O)C(OCC)Oc1ccc2ncccc2c1>>CCOC(Oc1ccc2ncccc2c1)C(=O)O -US20110077234A1,6,CCOC(=O)CSc1cnc(NC(=O)N(CC2CCCC2)c2cccc(OC(F)(F)F)c2)s1>>O=C(O)CSc1cnc(NC(=O)N(CC2CCCC2)c2cccc(OC(F)(F)F)c2)s1 -US20150104384A1,9,COC(=O)c1cc2c(Br)cncc2s1>>COC(=O)c1cc2ccncc2s1 -US20110136795A1,7,COc1ccc2ncc(F)c(C=O)c2n1>>COc1ccc2ncc(F)c(CO)c2n1 -US20150148340A1,6,CCOC(=O)c1cn(-c2ccc3c(c2)n(C)c(=O)n3C)c(=O)n(C2CCc3cc(OC)ccc32)c1=O>>COc1ccc2c(c1)CCC2n1c(=O)c(C(=O)O)cn(-c2ccc3c(c2)n(C)c(=O)n3C)c1=O -US20120270865A2,6,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(OC4CCSCC4)cc3c2C)C(C)C)cc1>>Cc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)cc2)C(C)C)oc2ccc(OC3CCSCC3)cc12 -US08466289B2,2,Cc1c(Nc2ccc(I)cc2F)c(N)c2n(c1=O)CCS2.O=S(=O)(Cl)C1(COCc2ccccc2)CC1>>Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2(COCc3ccccc3)CC2)c2n(c1=O)CCS2 -US20050203087A1,2,C=CCOC(=O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br.CC(C)O>>C=CCOC(=O)COc1c(C(=O)OC(C)C)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br -US04025630,1,CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CCC1.O=C(O)CCCN1CCCC1>>CCCCCC(C)C(C)c1cc(OC(=O)CCCN2CCCC2)c2c(c1)OC(C)(C)C1=C2CCC1 -US20150218181A1,2,CCOc1cc(C(=O)O)ccc1[N+](=O)[O-].NN>>CCOc1cc(C(=O)NN)ccc1[N+](=O)[O-] -US07160892B2,1,CI.Cn1c(N)nc(-c2cccc(F)c2)c(-c2ccc(=O)[nH]c2)c1=O>>Cn1cc(-c2c(-c3cccc(F)c3)nc(N)n(C)c2=O)ccc1=O -US20150094328A1,1,Fc1ccc(CBr)cc1.N#Cc1ccnc2c(C(=O)N[C@H]3CCCC[C@@H]3O)c[nH]c12>>N#Cc1ccnc2c(C(=O)N[C@H]3CCCC[C@@H]3O)cn(Cc3ccc(F)cc3)c12 -US20090143385A1,2,CCOC(=O)c1ccc(OCc2c(-c3ccncc3)noc2C)nn1.NC1CCOCC1>>Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)NC2CCOCC2)nn1 -US08648068B2,2,CN1CCC(N)CC1.Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3O[C@@H]3CCCOC3)c12>>Cc1c(C(=O)NC2CCN(C)CC2)sc2ncnc(Nc3ccc(F)cc3O[C@@H]3CCCOC3)c12 -US20140031345A1,2,CCOC(=O)CN.O=S(=O)(Cl)c1cncc(Br)c1>>CCOC(=O)CNS(=O)(=O)c1cncc(Br)c1 -US20060229336A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccccc1S(N)(=O)=O>>COC(=O)c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C -US20110275673A1,7,O=C(NCc1ccc(C#CCCCOc2ccc(F)cc2)cc1)C(F)(F)F>>O=C(NCc1ccc(CCCCCOc2ccc(F)cc2)cc1)C(F)(F)F -US20080096921A1,6,COC(=O)c1ccc2cc(-c3ccc(OCCCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)ccc2n1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCCOc1ccc(-c2ccc3nc(C(=O)O)ccc3c2)cc1 -US06455701B1,6,CCc1ccc(Oc2cc(C#C[Si](C)(C)C)ccc2C(C)(C)C)cc1>>C#Cc1ccc(C(C)(C)C)c(Oc2ccc(CC)cc2)c1 -US20130310357A1,1,CC(C)=O.CC(CF)(CF)c1cc(NC(=O)Nc2ccc(NC(=O)c3ccc(OC4CCNCC4)cn3)cc2)no1>>CC(C)N1CCC(Oc2ccc(C(=O)Nc3ccc(NC(=O)Nc4cc(C(C)(CF)CF)on4)cc3)nc2)CC1 -US08183262B2,3,FC(F)(F)c1cc(-c2ccc(Cl)cc2)nc(-c2cccc(Br)c2)n1.OB(O)c1cccnc1>>FC(F)(F)c1cc(-c2ccc(Cl)cc2)nc(-c2cccc(-c3cccnc3)c2)n1 -US07071358B2,3,C#CC(F)(F)F.CN(c1ccc(C(=O)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1>>CN(c1ccc(C(O)(C#CC(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1 -US20090181963A1,2,CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)O)cc4)cc3)nc21.CN1CCNCC1>>CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)N5CCN(C)CC5)cc4)cc3)nc21 -US07964613B2,2,CN(C)CCOCC(=O)N[C@H]1CCNC1.O=S(=O)(Cl)c1cccc2cncc(Cl)c12>>CN(C)CCOCC(=O)N[C@H]1CCN(S(=O)(=O)c2cccc3cncc(Cl)c23)C1 -US20150065507A1,3,C=CB1OC(C)(C)C(C)(C)O1.Cc1nc(Br)ccc1[N+](=O)[O-]>>C=Cc1ccc([N+](=O)[O-])c(C)n1 -US20070219210A1,9,CC(C)(C)OC(=O)NC1(C(=O)O)CCCC1.N>>CC(C)(C)OC(=O)NC1(C(N)=O)CCCC1 -US20080188502A1,1,CS(=O)(=O)c1ccc(Br)cn1.Cc1ncc(-c2nc(N)ncc2F)n1C1CCOCC1>>Cc1ncc(-c2nc(Nc3ccc(S(C)(=O)=O)nc3)ncc2F)n1C1CCOCC1 -US20100121048A1,3,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1C=O.c1ccc([P+](CC2CC2)(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1/C=C/C1CC1 -US04399136,2,COC(=O)C1C=CCN2C(=O)C(C)(CCO)C(=O)N12.CS(=O)(=O)Cl>>COC(=O)C1C=CCN2C(=O)C(C)(CCOS(C)(=O)=O)C(=O)N12 -US20020072536A1,3,C[Sn](C)(C)C.Nc1cc(Br)c2[nH]cnc2c1>>Cc1cc(N)cc2nc[nH]c12 -US08822471B2,2,Cc1nccn1-c1ccc(C(=O)O)cc1F.Clc1cnc(N2CCC(NC3CC3)CC2)nc1>>Cc1nccn1-c1ccc(C(=O)N(C2CC2)C2CCN(c3ncc(Cl)cn3)CC2)cc1F -US20070259951A1,2,COC(=O)c1cc(N)ccc1Br.CS(=O)(=O)Cl>>COC(=O)c1cc(NS(C)(=O)=O)ccc1Br -US20150175530A1,2,COC(=O)[C@@H](N)[C@@H](C)O.C[C@H](O)C#CC#Cc1ccc(C(=O)O)cc1>>COC(=O)[C@@H](NC(=O)c1ccc(C#CC#C[C@H](C)O)cc1)[C@@H](C)O -US07432288B2,4,CN(C)c1ccc(CN)cc1.O=C1OC(=O)C(c2ccccc2)=C1Cl>>CN(C)c1ccc(CN2C(=O)C(Cl)=C(c3ccccc3)C2=O)cc1 -US20150210682A1,3,CCCc1ccccc1OC.CN(C)C=O>>CCCc1cc(C=O)ccc1OC -US20110152315A1,3,C#Cc1ccc(C2CC2C(=O)OC)cc1.Cc1cccc(I)c1>>COC(=O)C1CC1c1ccc(C#Cc2cccc(C)c2)cc1 -US04963568,3,CCOC(=O)CP(=O)(OCC)OCC.O=CC1CCCCC1>>CCOC(=O)C=CC1CCCCC1 -US20060235057A1,2,CCC(=O)Cl.CCOC(=O)c1cc(N)cc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1>>CCOC(=O)c1cc(NC(=O)CC)cc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 -US06730672B2,2,CCOC(=O)C1CNCCN1Cc1ccccc1.O=C(Cl)C1CCN(c2ccncc2)CC1>>CCOC(=O)C1CN(C(=O)C2CCN(c3ccncc3)CC2)CCN1Cc1ccccc1 -US07795228B2,1,C=C(C)C[C@@]1(c2cc(Cc3ccc(CC)cc3)c(Cl)cc2O)O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CCc1ccc(Cc2cc3c(cc2Cl)OC(C)(C)C[C@]32O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1 -US20140057896A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCc2c(sc3c2CCCC3)C1=O.COCc1cc(Nc2cc(Br)cn(C)c2=O)nn1C>>COCc1cc(Nc2cc(-c3cccc(N4CCc5c(sc6c5CCCC6)C4=O)c3COC(C)=O)cn(C)c2=O)nn1C -US20150175623A1,6,CC(C)[Si](OCCN1CCN(CC(F)(F)F)CC1)(C(C)C)C(C)C>>OCCN1CCN(CC(F)(F)F)CC1 -US04730062,7,O=[N+]([O-])c1ccc2c(c1)C(F)(F)C(F)(F)O2>>Nc1ccc2c(c1)C(F)(F)C(F)(F)O2 -US06313346B1,1,C=CC(N)=O.CN(C)CCO>>CN(C)CCOCCC(N)=O -US08138197B2,2,O=C(O)c1cc(-c2nnn[nH]2)c2ccn(C3CC3)c2c1.O=C1CC2(CCNCC2)Oc2ccc(-c3ccc(=O)[nH]c3)cc21>>O=C1CC2(CCN(C(=O)c3cc(-c4nnn[nH]4)c4ccn(C5CC5)c4c3)CC2)Oc2ccc(-c3ccc(=O)[nH]c3)cc21 -US07241761B2,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.O=[N+]([O-])c1cccc2sc(N3CCNCC3)nc12>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2nc3c([N+](=O)[O-])cccc3s2)CC1 -US20110263571A1,1,CC1(C)CNC(=O)O1.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2F)CC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CC(C)(C)OC3=O)cc2F)CC1 -US20060094722A1,6,COC(=O)Cn1c(=O)n(C)c(=O)c2c1nc(N1CCN(C(=O)OC(C)(C)C)CC1)n2-c1ccccc1Cl>>Cn1c(=O)c2c(nc(N3CCN(C(=O)OC(C)(C)C)CC3)n2-c2ccccc2Cl)n(CC(=O)O)c1=O -US20110257151A1,2,CN(C)c1ccc(-c2cccc(C3Nc4c(cc(Cl)cc4C(=O)O)CC3(C)C)c2)cc1.NS(=O)(=O)C1CC1>>CN(C)c1ccc(-c2cccc(C3Nc4c(cc(Cl)cc4C(=O)NS(=O)(=O)C4CC4)CC3(C)C)c2)cc1 -US20150246922A1,3,Cc1c2n(c3c(Br)cc(C#N)cc13)CCCNC2=O.OB(O)c1cc(F)c(F)c(F)c1>>Cc1c2n(c3c(-c4cc(F)c(F)c(F)c4)cc(C#N)cc13)CCCNC2=O -US20080153828A1,1,CCC(CC)c1cc(C)nn2c(-c3cc4ccc(Cl)cc4[nH]3)c(C)nc12.CI>>CCC(CC)c1cc(C)nn2c(-c3cc4ccc(Cl)cc4n3C)c(C)nc12 -US07001895B2,3,CS(=O)(=O)c1ccc(-c2cnn(CC(F)(F)F)c(=O)c2Cl)cc1.OB(O)c1cc(Cl)cc(Cl)c1>>CS(=O)(=O)c1ccc(-c2cnn(CC(F)(F)F)c(=O)c2-c2cc(Cl)cc(Cl)c2)cc1 -US04066772,1,O=[N+]([O-])c1ccccc1NCCCCl.O=c1[nH]c2cc(Cl)ccc2n1C1CCNCC1>>O=c1[nH]c2cc(Cl)ccc2n1C1CCN(CCCNc2ccccc2[N+](=O)[O-])CC1 -US20080207587A1,2,O=C(Cl)c1ccccc1C(F)(F)F.O=C(NCCC1CC1)c1ccc(NC2CCNC2)nn1>>O=C(NCCC1CC1)c1ccc(NC2CCN(C(=O)c3ccccc3C(F)(F)F)C2)nn1 -US20150166564A1,3,CN(C)C=O.N#Cc1cc(F)cc(Br)c1>>N#Cc1cc(F)cc(C=O)c1 -US04263312,1,NNc1nc(C(Cl)(Cl)Cl)ns1.O=Cc1ccccc1O>>Oc1ccccc1C=NNc1nc(C(Cl)(Cl)Cl)ns1 -US20090291938A1,2,C=CC[C@H]1CN(C2CCCC2)c2nc(Nc3ccc(C(=O)O)cc3OC)ncc2N(C)C1=O.CN1CCC[C@H](N)C1>>C=CC[C@H]1CN(C2CCCC2)c2nc(Nc3ccc(C(=O)N[C@H]4CCCN(C)C4)cc3OC)ncc2N(C)C1=O -US20070254869A1,2,CC(=O)Cl.Cc1c(Cl)ccc2c1N(C(=O)OC(C)C)CCCC2NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2c1ccc(Cl)c2C -US09133181B2,6,COCOc1ccc(-c2cc(CN3CC(C)(C)N(Cc4ccccc4)CC3(C)C)c3c(C)nn(C4CCCCO4)c3n2)cc1>>COCOc1ccc(-c2cc(CN3CC(C)(C)NCC3(C)C)c3c(C)nn(C4CCCCO4)c3n2)cc1 -US20030232832A1,1,CCC(c1nn2cccc2c(=O)[nH]1)N(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc(C)cc1.Fc1cccc(CBr)c1>>CCC(c1nn2cccc2c(=O)n1Cc1cccc(F)c1)N(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc(C)cc1 -US05998433,3,C=O.CNC.c1ccc(CCCCCCN2CCCc3ccoc3C2)cc1>>CN(C)Cc1cc2c(o1)CN(CCCCCCc1ccccc1)CCC2 -US20060199800A1,1,CC#CCOc1cc(Cl)ncn1.CC1CCCCN1>>CC#CCOc1cc(N2CCCCC2C)ncn1 -US20110098296A1,7,O=[N+]([O-])c1cccc(-c2ncsc2-c2ccnc(Cl)n2)c1>>Nc1cccc(-c2ncsc2-c2ccnc(Cl)n2)c1 -US08026255B2,1,CCOc1cc(CN2CCC(=O)CC2)ccc1OC.CCc1ccc(N)cc1>>CCOc1cc(CN2CCC(Nc3ccc(CC)cc3)CC2)ccc1OC -US04820727,6,CCOC(=O)N(CC(=O)OC(C)(C)C)C(=O)c1c(Cl)ccc2c(C(F)(F)F)c(OC)ccc12>>CCOC(=O)N(CC(=O)O)C(=O)c1c(Cl)ccc2c(C(F)(F)F)c(OC)ccc12 -US08586746B2,2,NC1C2CC3CC1CN(C3)C2.O=C(O)c1ccc2[nH]ccc2c1>>O=C(NC1C2CC3CC1CN(C3)C2)c1ccc2[nH]ccc2c1 -US20110105514A1,1,CCc1nc(I)c2n1CCN(C(=O)OC(C)(C)C)C2CCc1ccc(C(F)(F)F)cc1.C[S-]>>CCc1nc(SC)c2n1CCN(C(=O)OC(C)(C)C)C2CCc1ccc(C(F)(F)F)cc1 -US07902187B2,7,CCOC(=O)c1nc(-n2cnc3ccc(F)cc32)nc(NC2CCOCC2)c1[N+](=O)[O-]>>CCOC(=O)c1nc(-n2cnc3ccc(F)cc32)nc(NC2CCOCC2)c1N -US06194438B1,2,N#Cc1ccc(C(=O)C=C2NC(Cc3ccncc3)(Cc3ccncc3)C(=O)N2CC2CCNCC2)cc1.O=S(=O)(Cl)c1cccs1>>N#Cc1ccc(C(=O)C=C2NC(Cc3ccncc3)(Cc3ccncc3)C(=O)N2CC2CCN(S(=O)(=O)c3cccs3)CC2)cc1 -US08481532B2,2,CCOC(=O)C1CC1c1ccc(C(C)(C)C)cc1.NN>>CC(C)(C)c1ccc(C2CC2C(=O)NN)cc1 -US20090286813A1,7,CCc1cccc(-n2c(N)c(N=O)c(=O)[nH]c2=S)c1>>CCc1cccc(-n2c(N)c(N)c(=O)[nH]c2=S)c1 -US06057369,2,C[C@H](C(=O)O)[C@H](O)CCCCc1ccccc1>>C[C@@H]1C(=O)O[C@@H]1CCCCc1ccccc1 -US20130059849A1,2,Cc1cc(C)c(CN)c(=O)[nH]1.Cc1nn(C2CCOCC2)c2nc(C3CC3)cc(C(=O)O)c12>>Cc1cc(C)c(CNC(=O)c2cc(C3CC3)nc3c2c(C)nn3C2CCOCC2)c(=O)[nH]1 -US05470851,1,C1CNCCN1.ClCCN1CCC(=C(c2ccccc2)c2ccccc2)CC1>>c1ccc(C(=C2CCN(CCN3CCNCC3)CC2)c2ccccc2)cc1 -US20080221127A1,3,Cc1nccn1S(=O)(=O)c1cccc(Br)c1.OB(O)c1ccc(C(F)(F)F)cc1F>>Cc1nccn1S(=O)(=O)c1cccc(-c2ccc(C(F)(F)F)cc2F)c1 -US20130059853A1,1,COc1ccc(-c2ccc3c(c2)COC3=O)c(O)c1OC(F)F.CS(=O)(=O)c1ccc(CBr)cc1>>COc1ccc(-c2ccc3c(c2)COC3=O)c(OCc2ccc(S(C)(=O)=O)cc2)c1OC(F)F -US20050234077A1,1,Fc1ccccc1CBr.Nc1cc(O)nc(S)n1>>Nc1cc(O)nc(SCc2ccccc2F)n1 -US20110237578A1,2,Cc1ccc(-c2cc(Br)cc(C(=O)O)c2)nc1.Cc1ccc(CN)cn1>>Cc1ccc(-c2cc(Br)cc(C(=O)NCc3ccc(C)nc3)c2)nc1 -US04902799,1,COc1ccc2cc(C(=O)C(C)Br)ccc2c1.c1ccc(CN2CCNCC2)cc1>>COc1ccc2cc(C(=O)C(C)N3CCN(Cc4ccccc4)CC3)ccc2c1 -US04571396,1,C1CC2CNC1CN2.CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CC4CCC3CN4)c(F)c21 -US07094779B2,6,C1CCC(OCC2=NOC(CN3CCOCC3)C2)OC1>>OCC1=NOC(CN2CCOCC2)C1 -US07517875B2,7,COC(=O)c1ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>COC(=O)c1ccc(NC(=O)OC(C)(C)C)c(N)c1 -US08067589B2,2,CC(C)(C)C(=O)Cl.O=C(NC1CNC1)c1cnc(-c2cccc(F)c2)nc1>>CC(C)(C)C(=O)N1CC(NC(=O)c2cnc(-c3cccc(F)c3)nc2)C1 -US05482967,1,CC1(c2ccccc2)CC(=O)Nc2ccc(Cl)cc21.CI>>CN1C(=O)CC(C)(c2ccccc2)c2cc(Cl)ccc21 -US20040072871A1,3,O=Cc1cc(Br)cs1.OB(O)c1ccc(OC(F)(F)F)cc1>>O=Cc1cc(-c2ccc(OC(F)(F)F)cc2)cs1 -US06051712,2,COc1ccccc1COc1cc(COC2CN(C(=O)OC(C)(C)C)CCC2c2ccc(OCCO)cc2)cc2ccccc12.O=C(Cl)c1ccccc1>>COc1ccccc1COc1cc(COC2CN(C(=O)OC(C)(C)C)CCC2c2ccc(OCCOC(=O)c3ccccc3)cc2)cc2ccccc12 -US20030191279A1,6,O=C1c2ccccc2C(=O)N1CC(=O)N(Cc1ccccc1)C1c2ccccc2OCC1Cc1ccccc1>>NCC(=O)N(Cc1ccccc1)C1c2ccccc2OCC1Cc1ccccc1 -US08637525B2,1,CNC.Clc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1>>CN(C)c1nc(Cl)nc2c1CCC2c1ccc(Cl)cc1 -US20140288123A1,2,CC(Oc1ccc(F)cc1F)c1ccc(C(=O)O)cc1.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(C(C)Oc3ccc(F)cc3F)cc2)c(O)n1 -US06949648B2,1,COC(=O)c1c(Br)ccc(F)c1F.Cc1cc(N)n(-c2ccccn2)n1>>COC(=O)c1c(Nc2cc(C)nn2-c2ccccn2)ccc(F)c1F -US04904690,2,CC(C)(C)CO.O=C(O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12>>CC(C)(C)COC(=O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12 -US20120178736A1,2,CC(C)(C)N1CCNCC1.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)O)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)N3CCN(C(C)(C)C)CC3)n(C)c2n1 -US20150210688A1,2,COc1nnc(-c2cc(C(=O)O)c(C)cc2C2CCC2)[nH]1.N#Cc1ccc(C2(F)CNC2)cc1>>COc1nnc(-c2cc(C(=O)N3CC(F)(c4ccc(C#N)cc4)C3)c(C)cc2C2CCC2)[nH]1 -US20150274725A1,7,CCOc1cc(CNc2ncc(I)cc2[N+](=O)[O-])ccc1OCc1ccc(OC)nc1>>CCOc1cc(CNc2ncc(I)cc2N)ccc1OCc1ccc(OC)nc1 -US04900728,2,NC1C(=O)NC1CCl.O=C(O)C(=NOC(c1ccccc1)(c1ccccc1)c1ccccc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(NC1C(=O)NC1CCl)C(=NOC(c1ccccc1)(c1ccccc1)c1ccccc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US20100160323A1,2,NCC(=O)N1CCN(C(=O)c2cc(F)ccc2C(F)(F)F)CC1.O=C(O)c1cn2ccccc2n1>>O=C(NCC(=O)N1CCN(C(=O)c2cc(F)ccc2C(F)(F)F)CC1)c1cn2ccccc2n1 -US20130190330A1,7,CCOC(=O)c1cncn1Cc1c(Cl)cccc1Cl>>OCc1cncn1Cc1c(Cl)cccc1Cl -US20050026925A1,7,Cc1nc2c(cc1C=O)C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N21>>Cc1nc2c(cc1CO)C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N21 -US05312820,2,O=C(Cl)Cl.c1ccc2c(c1)CCCN2>>O=C(Cl)N1CCCc2ccccc21 -US07589103B2,1,CCN(CC)C(=O)c1ccc2c(c1)Oc1ccccc1C2=C1CC2CCC(C1)N2.O=Cc1ccoc1>>CCN(CC)C(=O)c1ccc2c(c1)Oc1ccccc1C2=C1CC2CCC(C1)N2Cc1ccoc1 -US20140235658A1,7,C#Cc1cccc(Nc2ncnc3cc(OCC)c([N+](=O)[O-])cc23)c1>>C#Cc1cccc(Nc2ncnc3cc(OCC)c(N)cc23)c1 -US06004988,6,CCOC(=O)CC(C)(c1ccccc1)c1ccccc1>>CC(CC(=O)O)(c1ccccc1)c1ccccc1 -US06300352B1,1,CCOC(=O)[C@H](C)O.Oc1ccc(-c2ccccc2)cc1>>CCOC(=O)[C@@H](C)Oc1ccc(-c2ccccc2)cc1 -US20090291988A1,9,N.O=C(O)C1(c2ccc(Br)cc2)CC1>>NC(=O)C1(c2ccc(Br)cc2)CC1 -US20140088084A1,1,C[C@@](CO)(NC(=O)CCl)c1cc(Br)cc([N+](=O)[O-])c1>>C[C@@]1(c2cc(Br)cc([N+](=O)[O-])c2)COCC(=O)N1 -US05616594,6,COc1ccc(-c2nc(-c3c(F)cccc3Cl)nn2C)cc1Cl>>Cn1nc(-c2c(F)cccc2Cl)nc1-c1ccc(O)c(Cl)c1 -US06759408B2,1,CC1(C)OC(=O)Nc2ccc(-c3cccc(Br)c3)cc21.CI>>CN1C(=O)OC(C)(C)c2cc(-c3cccc(Br)c3)ccc21 -US05496843,6,COC(=O)c1[nH]c2cc(Cl)cc3c2c1C(CC(=O)OC(C)(C)C)CC3>>COC(=O)c1[nH]c2cc(Cl)cc3c2c1C(CC(=O)O)CC3 -US07064203B2,1,NC(=O)c1cc([N+](=O)[O-])ccc1Cl.OCc1cccc(F)c1>>NC(=O)c1cc([N+](=O)[O-])ccc1OCc1cccc(F)c1 -US08080566B1,3,O=Cc1cccc([N+](=O)[O-])c1Cl.OB(O)c1ccccc1>>O=Cc1cccc([N+](=O)[O-])c1-c1ccccc1 -US08470828B2,5,N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1)C(F)(F)F -US20150284387A1,6,CCOC(=O)c1cc(NCc2ccco2)nc2c1c(C)nn2Cc1ccc(Oc2ccccc2)cc1>>Cc1nn(Cc2ccc(Oc3ccccc3)cc2)c2nc(NCc3ccco3)cc(C(=O)O)c12 -US20080076774A1,1,Cc1c(I)cc(Cl)cc1N1CCN(C(=O)OC(C)(C)C)CC1.NCCN1CCCC1>>Cc1c(NCCN2CCCC2)cc(Cl)cc1N1CCN(C(=O)OC(C)(C)C)CC1 -US07423185B2,2,CS(=O)(=O)Cl.Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C)c1OCCO>>Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C)c1OCCOS(C)(=O)=O -US06117889,2,COC(=O)Cl.c1cc[nH]c1>>COC(=O)n1cccc1 -US20080171743A1,6,CCNC(=O)Nc1ccc(-c2nc(CO[Si](C)(C)C(C)(C)C)cc(N3CCOC[C@@H]3C)n2)cc1>>CCNC(=O)Nc1ccc(-c2nc(CO)cc(N3CCOC[C@@H]3C)n2)cc1 -US20080027050A1,6,CCOC(=O)c1ccc(COCc2csc3nc(C(=O)NCc4ccc(F)c(Cl)c4)[nH]c(=O)c23)cc1>>O=C(O)c1ccc(COCc2csc3nc(C(=O)NCc4ccc(F)c(Cl)c4)[nH]c(=O)c23)cc1 -US20100004292A1,2,COC(=O)c1ccc(F)cc1N.O=C(Cl)c1ccc(Cl)s1>>COC(=O)c1ccc(F)cc1NC(=O)c1ccc(Cl)s1 -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(Oc3cnc(C(=O)OC)cn3)cc(C)c21>>CCOC(=O)CC1OB(O)c2cc(Oc3cnc(C(=O)O)cn3)cc(C)c21 -US20140179668A1,2,COC(=O)[C@@H]1C[C@@H](O)CN1c1nc2c(c(Nc3cc(C(C)C)[nH]n3)n1)CCC2.Nc1ccc(F)nc1>>CC(C)c1cc(Nc2nc(N3C[C@H](O)C[C@H]3C(=O)Nc3ccc(F)nc3)nc3c2CCC3)n[nH]1 -US20130225584A1,3,Cn1cc(B(O)O)cn1.O=C(Nc1ccnnc1)c1cc(Br)c(CN2CCOCC2)cc1OCc1ccccc1>>Cn1cc(-c2cc(C(=O)Nc3ccnnc3)c(OCc3ccccc3)cc2CN2CCOCC2)cn1 -US04931455,2,CCOC(=O)Cl.CCc1ncnc(NCCCCCCO)c1Cl>>CCOC(=O)OCCCCCCNc1ncnc(CC)c1Cl -US08598173B2,2,CCOC(=O)Nc1nc2ccc(OC)cc2nc1OC.Cc1cc(C)cc(N2CCNCC2)c1>>COc1ccc2nc(NC(=O)N3CCN(c4cc(C)cc(C)c4)CC3)c(OC)nc2c1 -US08389513B2,2,CC1(C)OC(N)=N[C@](C)(c2cc(N)ccc2F)C1(F)F.O=C(O)c1ccn(C(F)F)n1>>CC1(C)OC(N)=N[C@](C)(c2cc(NC(=O)c3ccn(C(F)F)n3)ccc2F)C1(F)F -US20120295884A1,6,COC(=O)c1ccc2c(C(C)=O)nn(CC(=O)OC(C)(C)C)c2c1>>COC(=O)c1ccc2c(C(C)=O)nn(CC(=O)O)c2c1 -US07919502B2,1,FC(F)(F)Oc1ccccc1CBr.O=C1CNc2ncc(I)cc2N1>>O=C1CNc2ncc(I)cc2N1Cc1ccccc1OC(F)(F)F -US20150259366A1,2,CCCCCCCc1ccc(CNc2ccc(O)c(C(=O)OC)c2)cc1.O=C(Cl)c1ccncc1>>CCCCCCCc1ccc(CN(C(=O)c2ccncc2)c2ccc(O)c(C(=O)OC)c2)cc1 -US20110034526A1,1,CS(=O)(=O)c1cccc(F)c1.Cc1nc2c(Cl)cccc2n1-c1cc(O)ccc1Cl>>Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cccc(S(C)(=O)=O)c2)ccc1Cl -US20090176781A1,3,C#Cc1ccc(NC(C)=O)nc1.CCOC(=O)c1ccc(C)c(I)c1>>CCOC(=O)c1ccc(C)c(C#Cc2ccc(NC(C)=O)nc2)c1 -US07749530B2,1,Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)c2)n(C(C)(C)C)n1.Nc1cccc(O)c1>>Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CNc3cccc(O)c3)c2)n(C(C)(C)C)n1 -US07649093B2,3,CCCc1cc2cc(OC)ccc2c(Oc2ccc(C=O)cc2)c1-c1ccccc1.CCOC(=O)CP(=O)(OCC)OCC>>CCCc1cc2cc(OC)ccc2c(Oc2ccc(/C=C/C(=O)OCC)cc2)c1-c1ccccc1 -US07115611B2,2,CS(=O)(=O)Cl.Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1CO>>Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1COS(C)(=O)=O -US20150225381A1,2,CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(Oc2ccccc2C(=O)O)c(F)c1.CN>>CNC(=O)c1ccccc1Oc1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1F -US20080161366A1,1,CN.O=S1(=O)N(CCCBr)c2ccccc2N1c1ccccc1>>CNCCCN1c2ccccc2N(c2ccccc2)S1(=O)=O -US07935699B2,2,C=CCN.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2ccn(CCC(=O)O)n2)cc1Cl>>C=CCNC(=O)CCn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)n1 -US20130338134A1,1,C1COCCN1.COc1cc(OC)c(F)c(N2Cc3cnc4c(cc(C=O)n4S(=O)(=O)c4ccccc4)c3C(C)(C)C2=O)c1F>>COc1cc(OC)c(F)c(N2Cc3cnc4c(cc(CN5CCOCC5)n4S(=O)(=O)c4ccccc4)c3C(C)(C)C2=O)c1F -US20150266867A1,6,COc1ccc(CN2C(=O)[C@@H](NC(=O)OCc3ccccc3)[C@H]2CN2C(=O)c3ccccc3C2=O)c(OC)c1>>COc1ccc(CN2C(=O)[C@@H](NC(=O)OCc3ccccc3)[C@H]2CN)c(OC)c1 -US20010031788A1,7,CCOC(=O)CC(NC(=O)C(CC)c1ccccc1)c1cccc(NS(=O)(=O)c2cccc([N+](=O)[O-])c2)c1>>CCOC(=O)CC(NC(=O)C(CC)c1ccccc1)c1cccc(NS(=O)(=O)c2cccc(N)c2)c1 -US05153210,6,CC(COc1ccc(OCC2=NCCN2)cc1)NCC(O)c1ccc(OCc2ccccc2)cc1>>CC(COc1ccc(OCC2=NCCN2)cc1)NCC(O)c1ccc(O)cc1 -US20130303788A1,6,C=CCc1ccc(OC)c(-c2ccc(O)c(CC=C)c2)c1>>C=CCc1ccc(O)c(-c2ccc(O)c(CC=C)c2)c1 -US08183262B2,3,FC(F)(F)c1cccc(-c2cc(C(F)(F)F)nc(Cl)n2)c1.OB(O)c1cccc(Br)c1>>FC(F)(F)c1cccc(-c2cc(C(F)(F)F)nc(-c3cccc(Br)c3)n2)c1 -US07781591B2,3,CCCC[Sn](CCCC)(CCCC)c1nccs1.Cc1c(Nc2c(I)cncc2C#N)ccc2[nH]ccc12>>Cc1c(Nc2c(C#N)cncc2-c2nccs2)ccc2[nH]ccc12 -US20130045165A1,2,CC(C)(C)N=C=O.Nc1cccc(C2(F)CCN(CCOc3ccccc3)CC2)c1>>CC(C)(C)NC(=O)Nc1cccc(C2(F)CCN(CCOc3ccccc3)CC2)c1 -US04661603,7,O=C(c1ccc(Cl)cc1)c1cccnc1-n1ccnc1>>OC(c1ccc(Cl)cc1)c1cccnc1-n1ccnc1 -US20130123253A1,9,COc1ccc(F)cc1CCC1CCC(CBr)O1.[C-]#N>>COc1ccc(F)cc1CC[C@H]1CC[C@H](CC#N)O1 -US03984467,7,CCCCC(=N)NC(=O)Nc1ccc([N+](=O)[O-])cc1>>CCCCC(=N)NC(=O)Nc1ccc(N)cc1 -US08088790B2,9,N.Oc1nc2c(Cl)nc3ccccc3c2n1Cc1cccnc1>>Nc1nc2ccccc2c2c1nc(O)n2Cc1cccnc1 -US08106215B2,2,Cc1nc(C(=O)O)c(-c2ccc(C(F)(F)F)cc2)s1.Cc1nc2sccn2c1C(=O)NC[C@H]1NC[C@@H]2CCC[C@H]12>>Cc1nc(C(=O)N2C[C@@H]3CCC[C@@H]3[C@H]2CNC(=O)c2c(C)nc3sccn23)c(-c2ccc(C(F)(F)F)cc2)s1 -US20050113357A1,7,O=C(O)CCc1c[nH]c2ccccc12>>OCCCc1c[nH]c2ccccc12 -US20030125220A1,2,CC(=CC(=O)O)c1ccc(O)cc1O.OCCc1ccccc1>>C/C(=C\C(=O)OCCc1ccccc1)c1ccc(O)cc1O -US04816452,4,CCOC(=O)/C(=N\O[C@@H]1CC[C@@H](C)CC1)C(=O)CBr.NC(N)=S>>CCOC(=O)/C(=N\O[C@@H]1CC[C@@H](C)CC1)c1csc(N)n1 -US20080269256A1,1,CCOC(=O)c1nc(C)ccc1Br.Nc1cccnc1>>CCOC(=O)c1nc(C)ccc1Nc1cccnc1 -US20110257151A1,6,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccccc1NC(=O)c1ccccn1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1ccccc1NC(=O)c1ccccn1 -US04803280,2,CC(C)(C)CC(=O)Cl.COC(=O)NN>>COC(=O)NNC(=O)CC(C)(C)C -US07935724B2,6,CCOC(=O)c1cc2ccc(C(=O)OC)cc2s1>>CCOC(=O)c1cc2ccc(C(=O)O)cc2s1 -US20100152165A1,7,COC(=O)c1ccc2cccnc2c1C>>COC(=O)c1ccc2c(c1C)NCCC2 -US08288419B2,1,CC1(c2cccc(COS(C)(=O)=O)c2)OCCO1.O=[N+]([O-])c1cn[nH]c1>>CC1(c2cccc(Cn3cc([N+](=O)[O-])cn3)c2)OCCO1 -US20090264431A1,2,COc1ccc(OC)c(S(=O)(=O)Cl)c1.C[C@H]1C[C@@H](N)CN1C(=O)OC(C)(C)C>>COc1ccc(OC)c(S(=O)(=O)N[C@@H]2C[C@H](C)N(C(=O)OC(C)(C)C)C2)c1 -US07056943B2,6,CCOC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3ccc(OC(F)(F)F)cc3)cc12>>O=C(O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3ccc(OC(F)(F)F)cc3)cc12 -US20060074086A1,7,CCNC(=O)NCc1cccc(-c2ccc(C(C)(C)CCCNC(=O)C(C)(C)C)cc2O)c1>>CCNC(=O)NCc1cccc(-c2ccc(C(C)(C)CCCNCC(C)(C)C)cc2O)c1 -US08637501B2,6,Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nn5)cc4=O)nc31)CCN(C(=O)OC(C)(C)C)CC2>>Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nn5)cc4=O)nc31)CCNCC2 -US07378417B2,2,Nc1cccc(S(=O)(=O)NCC2CC2)c1.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>O=C(Nc1cccc(S(=O)(=O)NCC2CC2)c1)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12 -US06297252B1,2,CC(=O)Cl.COc1ccc(-c2ncc3n2CNc2ccccc2-3)cc1>>COc1ccc(-c2ncc3n2CN(C(C)=O)c2ccccc2-3)cc1 -US05703240,1,CI.O=Cc1cc(-n2cnnn2)ccc1O>>COc1ccc(-n2cnnn2)cc1C=O -US20100273797A1,1,CC(C)(C)c1cc(Cl)c(O)c([N+](=O)[O-])c1.CI>>COc1c(Cl)cc(C(C)(C)C)cc1[N+](=O)[O-] -US04931083,6,CCOC(=O)C(C)Oc1ncn(-c2ccc(Cl)c(Cl)c2)n1>>CC(Oc1ncn(-c2ccc(Cl)c(Cl)c2)n1)C(=O)O -US20060030583A1,3,C1COCCN1.C=O.COc1ccccc1-c1c[nH]c2ncc(-c3cccc(O)c3)cc12>>COc1ccccc1-c1c[nH]c2ncc(-c3ccc(CN4CCOCC4)c(O)c3)cc12 -US06803374B2,2,NS(=O)(=O)c1ccc2c(c1)nc(-c1ccc(OCc3ccccc3)cc1)n2C1CCCCC1.O=C(Cl)c1ccccc1>>O=C(NS(=O)(=O)c1ccc2c(c1)nc(-c1ccc(OCc3ccccc3)cc1)n2C1CCCCC1)c1ccccc1 -US07625908B2,2,CC(C)(O)C(=O)O.CNC[C@@H](C)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>C[C@H](CN(C)C(=O)C(C)(C)O)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12 -US20070129416A1,2,CCOc1cc(C(F)(F)F)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.O=C(CN1CCNCC1)N1CCOCC1>>CCOc1cc(C(F)(F)F)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N2CCOCC2)CC1 -US20140005232A1,1,CC(C)(C)N.O=[N+]([O-])c1ccc(Br)cc1F>>CC(C)(C)Nc1cc(Br)ccc1[N+](=O)[O-] -US04168964,8,Cc1[nH]c(-c2cccc(C(F)(F)F)c2)nc1CO>>Cc1[nH]c(-c2cccc(C(F)(F)F)c2)nc1C=O -US20030232849A1,7,COc1ccc(Oc2ccc([N+](=O)[O-])c(C)c2)cc1>>COc1ccc(Oc2ccc(N)c(C)c2)cc1 -US04035376,3,Fc1ccccc1.O=C(Cl)c1cccnc1>>O=C(c1ccc(F)cc1)c1cccnc1 -US07585985B2,3,COC(=O)C1=C(OS(=O)(=O)C(F)(F)F)C[C@H](C)C1.COCOc1ccc(OCOC)c(B(O)O)c1>>COCOc1ccc(OCOC)c(C2=C(C(=O)OC)C[C@@H](C)C2)c1 -US20110224447A1,1,CCCCC/C=C\C/C=C\CCCCCCCCO.ClC[C@H]1CO1>>CCCCC/C=C\C/C=C\CCCCCCCCOC[C@H]1CO1 -US04278676,5,CCOC(=O)C1CCN(C(=O)OC)CC1=O.OCCO>>CCOC1(C2CCN(C(=O)OC)CC2=O)OCCO1 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)cn3)c(F)c2)OC1(C)C.CCCCCCS(=O)(=O)c1ccccc1Br>>CCCCCCS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 -US07253198B2,1,CC(C)(COS(C)(=O)=O)NC(=O)OC(C)(C)C.Oc1ccccc1>>CC(C)(COc1ccccc1)NC(=O)OC(C)(C)C -US04239903,1,CCNC1CCc2cc(OC)ccc2C1.COc1cc(C(=O)OCCCCI)cc(OC)c1OC>>CCN(CCCCOC(=O)c1cc(OC)c(OC)c(OC)c1)C1CCc2cc(OC)ccc2C1 -US07064120B2,2,NCc1ccncc1.O=C(O)c1ccc2n1Cc1ccccc1N(C(=O)c1ccc(-c3cccc4ccccc34)cc1Cl)C2>>O=C(NCc1ccncc1)c1ccc2n1Cc1ccccc1N(C(=O)c1ccc(-c3cccc4ccccc34)cc1Cl)C2 -US20070004764A1,1,O=C1c2ccccc2C(=O)N1CCCBr.OC1CCNCC1>>O=C1c2ccccc2C(=O)N1CCCN1CCC(O)CC1 -US20060160832A1,1,CNC(=O)c1cc2c(Cl)ccnc2cc1OCc1ccccc1.Nc1ccc(O)cc1Cl>>CNC(=O)c1cc2c(Oc3ccc(N)c(Cl)c3)ccnc2cc1OCc1ccccc1 -US03994858,1,CC1(C)NC(=O)NC1=O.ClCCCl>>CC1(C)NC(=O)N(CCCl)C1=O -US20140228365A1,2,COC(=O)c1cccc([N+](=O)[O-])c1.NN>>NNC(=O)c1cccc([N+](=O)[O-])c1 -US20070232615A1,1,CN(Cc1cn2c(F)cccc2n1)C1CCCc2cccnc21.CNC1CCN(C)CC1>>CN1CCC(N(C)c2cccc3nc(CN(C)C4CCCc5cccnc54)cn23)CC1 -US20130109665A1,2,CC(C)(N)CCc1ccncc1.O=C(O)c1cnc(C2CC2)c(OCC2CC2)n1>>CC(C)(CCc1ccncc1)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 -US20080004312A1,6,CC(C)(C)OC(=O)NC(C)(C)C(=O)N1CCc2ccccc2C1>>CC(C)(N)C(=O)N1CCc2ccccc2C1 -US08093435B2,2,CC(C)O.COc1ccc(CC(=O)O)cc1>>COc1ccc(CC(=O)OC(C)C)cc1 -US07087597B1,1,CCOC(=O)c1cnc(N2CCc3ccccc32)nc1Cl.NCc1ccc(F)cc1>>CCOC(=O)c1cnc(N2CCc3ccccc32)nc1NCc1ccc(F)cc1 -US20140323468A1,6,COc1ccncc1-c1cnc2c(c1)CCCN2C(=O)OC(C)(C)C>>COc1ccncc1-c1cnc2c(c1)CCCN2 -US06506772B1,2,NCc1cc(N)nc(N)c1.O=C(O)C1CCCC1>>Nc1cc(CNC(=O)C2CCCC2)cc(N)n1 -US06630600B1,3,CCOC(=O)C(OCC)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COc1cc(C=O)ccc1OCc1ccccc1>>CCOC(=O)C(=Cc1ccc(OCc2ccccc2)c(OC)c1)OCC -US08546427B2,2,CC1(C)CC(c2ccccc2N)Nc2ccc(C(F)(F)F)cc21.O=S(=O)(Cl)c1ccc(F)cc1>>CC1(C)CC(c2ccccc2NS(=O)(=O)c2ccc(F)cc2)Nc2ccc(C(F)(F)F)cc21 -US20110044943A1,1,Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F.O=C(O)c1cccc(COc2ccc(-c3cc(CCl)on3)cc2)c1>>O=C(O)c1cccc(COc2ccc(-c3cc(Cn4cc5nc(-c6cccc(F)c6F)nc-5cn4)on3)cc2)c1 -US07202263B2,1,COc1ccc(C=O)c2ccccc12.c1cn(-c2ccc(OC3CCCNC3)cc2)cn1>>COc1ccc(CN2CCCC(Oc3ccc(-n4ccnc4)cc3)C2)c2ccccc12 -US20090247567A1,2,CNc1ccccc1Cl.O=C(O)c1cc2c(s1)-c1ccc(Br)cc1OCC2>>CN(C(=O)c1cc2c(s1)-c1ccc(Br)cc1OCC2)c1ccccc1Cl -US07732618B2,6,CCCc1nc2cc(N(Cc3cccc(Cl)c3)S(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C>>CCCc1nc2cc(N(Cc3cccc(Cl)c3)S(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)O -US20020052511A1,1,CC1(C)NC(=O)NC1=O.COc1ccc(/C=N/[C@@H](CO)COc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)cc1>>COc1ccc(/C=N/[C@H](COc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)CN2C(=O)NC(C)(C)C2=O)cc1 -US20100331297A1,2,CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc21.O=C(O)C(=O)c1ccccc1>>CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(NC(=O)C(=O)c3ccccc3)ncnc21 -US05466710,1,C#CCBr.O=C(O)CCS>>C#CCSCCC(=O)O -US07229987B2,8,COc1ccc(-c2nc(C)c(CO)o2)cc1>>COc1ccc(-c2nc(C)c(C=O)o2)cc1 -US20150191452A1,1,CC(C)(C)[Si](C)(C)O[C@H]1CCNC1=O.Clc1ccc(CBr)cc1>>CC(C)(C)[Si](C)(C)O[C@H]1CCN(Cc2ccc(Cl)cc2)C1=O -US08013156B2,2,O=C=Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1.c1cc(COc2nsnc2N2CCNCC2)ccn1>>O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(c2nsnc2OCc2ccncc2)CC1 -US07947676B2,2,CNCCOc1n[nH]c2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12.O=C(O)CO>>CN(CCOc1n[nH]c2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12)C(=O)CO -US08455525B2,2,COc1cccc(C(=O)NN)c1.Cc1c(N[C@@H](C(=O)O)[C@H](C)O)ccc(C#N)c1Cl>>COc1cccc(C(=O)NNC(=O)[C@H](Nc2ccc(C#N)c(Cl)c2C)[C@H](C)O)c1 -US04054719,1,CC(=O)O.Cc1ccc(C(=O)CBr)cc1>>CC(=O)OCC(=O)c1ccc(C)cc1 -US07253286B2,7,COc1cc2nccc(Oc3ccc([N+](=O)[O-])cn3)c2cc1OC>>COc1cc2nccc(Oc3ccc(N)cn3)c2cc1OC -US20110190365A1,2,NCC(F)(F)F.O=C(O)c1ccc(-n2cc(-c3cc(Cl)cc(Cl)c3)c(C(F)(F)F)n2)cc1C(F)(F)F>>O=C(NCC(F)(F)F)c1ccc(-n2cc(-c3cc(Cl)cc(Cl)c3)c(C(F)(F)F)n2)cc1C(F)(F)F -US20140329829A1,6,C[C@H](O)[C@@H](O)c1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)c(F)c1>>C[C@H](O)[C@@H](O)c1cnc(N2CCNCC2)c(F)c1 -US05576313,6,OC1(Cc2ccccc2)CCN(Cc2ccccc2)CC1>>OC1(Cc2ccccc2)CCNCC1 -US05731322,1,CCCCBr.COc1cccc([C@]23CCNC[C@@H]2CCC(=O)C3)c1>>CCCCN1CC[C@]2(c3cccc(OC)c3)CC(=O)CC[C@H]2C1 -US08153807B2,2,CC(C)[Si](OC1CCN(N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(C(=O)O)cc4)cc3Cl)C2=O)CC1)(C(C)C)C(C)C.FC1(F)CCNCC1>>CC(C)[Si](OC1CCN(N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(C(=O)N5CCC(F)(F)CC5)cc4)cc3Cl)C2=O)CC1)(C(C)C)C(C)C -US20080051398A1,1,CN.COc1ccc(N(C)c2nc(Cl)nc3ccccc23)cn1>>CNc1nc(N(C)c2ccc(OC)nc2)c2ccccc2n1 -US20110182850A1,2,CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)C.CCCC1(S(=O)(=O)NC(=O)[C@@]2(NC(=O)[C@@H]3C[C@@]4(CN3)C(C)(C)C43CCC3)C[C@@H]2CC)CC1>>CCCC1(S(=O)(=O)NC(=O)[C@@]2(NC(=O)[C@@H]3C[C@@]4(CN3C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)C(C)(C)C43CCC3)C[C@@H]2CC)CC1 -US08247429B2,3,C=CC(=O)OC.COC(=O)c1c(Br)ccc2nn(C)c(C)c12>>COC(=O)/C=C/c1ccc2nn(C)c(C)c2c1C(=O)OC -US20130217666A1,1,CCOC(=O)c1nc2c(s1)C(O)COc1ccc(Br)cc1-2.CI>>CCOC(=O)c1nc2c(s1)C(OC)COc1ccc(Br)cc1-2 -US20100317657A1,3,CCn1cc(-n2c(=O)n(C)c3cnc4ccc(Br)cc4c32)c(C)n1.OCc1ccc(B(O)O)cn1>>CCn1cc(-n2c(=O)n(C)c3cnc4ccc(-c5ccc(CO)nc5)cc4c32)c(C)n1 -US20140121200A1,1,Clc1cc2nccnc2c(Cl)n1.O=C(OCC1c2ccccc2-c2ccccc21)N1CCC2CNCC21>>O=C(OCC1c2ccccc2-c2ccccc21)N1CCC2CN(c3nc(Cl)cc4nccnc34)CC21 -US08354413B2,1,COC(=O)c1cc(CBr)ccc1F.O=c1cn[nH]c2ccccc12>>COC(=O)c1cc(Cn2ncc(=O)c3ccccc32)ccc1F -US20060160858A1,6,COC(=O)c1ccccc1Nc1ccc2c(C#Cc3ccccn3)nn(COCC[Si](C)(C)C)c2c1>>C[Si](C)(C)CCOCn1nc(C#Cc2ccccn2)c2ccc(Nc3ccccc3C(=O)O)cc21 -US08283340B2,2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.OCc1cc2ccccc2o1>>O=C(OCc1cc2ccccc2o1)Oc1ccc([N+](=O)[O-])cc1 -US20130261128A1,6,C[Si](C)(C)CCOCn1cc(C(F)(F)F)nc1-c1ccc(-c2ccc(OCc3ccccc3)cc2)nc1>>C[Si](C)(C)CCOCn1cc(C(F)(F)F)nc1-c1ccc(-c2ccc(O)cc2)nc1 -US08232284B2,2,CNCCCN(C)C.O=S(=O)(Cl)c1cnc(Cl)c(Cl)c1>>CN(C)CCCN(C)S(=O)(=O)c1cnc(Cl)c(Cl)c1 -US05591694,9,Fc1nc(F)c(OC(F)F)c(Cl)n1.N>>Nc1nc(F)c(OC(F)F)c(Cl)n1 -US20020002190A1,2,Nc1nccs1.O=C(O)C(CC1CCCC1)c1ccc(-c2cccnc2)cc1>>O=C(Nc1nccs1)C(CC1CCCC1)c1ccc(-c2cccnc2)cc1 -US08975256B2,1,COc1cc(OC(=O)c2ccccc2C)ccc1-c1ccc2c(c1CO)NC(=O)C(C)(C)N2.COc1ccc([N+](=O)[O-])cc1O>>COc1ccc([N+](=O)[O-])cc1OCc1c(-c2ccc(OC(=O)c3ccccc3C)cc2OC)ccc2c1NC(=O)C(C)(C)N2 -US20110152296A1,4,COC(=O)CC(=O)c1ccccc1S(C)(=O)=O.Nc1cc(F)cnc1C=O>>COC(=O)c1cc2ncc(F)cc2nc1-c1ccccc1S(C)(=O)=O -US20120094995A1,2,CN1C2CCC1(C(N)c1ccccc1)CC2.Cc1cccc(F)c1C(=O)O>>Cc1cccc(F)c1C(=O)N[C@H](c1ccccc1)C12CCC(CC1)N2C -US20120252801A1,6,CCN1CC(C)(c2ccccc2)OC(=O)C1CC(=O)OC(C)(C)C>>CCN1CC(C)(c2ccccc2)OC(=O)C1CC(=O)O -US20050014812A1,1,CCOC(=O)CCCOc1cc(C)c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(N)c1.ClCc1ccc(Cl)cc1Cl>>CCOC(=O)CCCOc1cc(C)c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(NCc2ccc(Cl)cc2Cl)c1 -US06867321B2,7,O=C1CO[C@@H]2OCC[C@@H]12>>O[C@@H]1CO[C@@H]2OCC[C@H]12 -US04782176,1,CCCc1c(O)ccc(C(C)=O)c1O.CCCc1c(OCCCC(=O)OCC)ccc(C(C)=O)c1OCCOCCOCCOS(C)(=O)=O>>CCCc1c(OCCOCCOCCOc2c(C(C)=O)ccc(OCCCC(=O)OCC)c2CCC)ccc(C(C)=O)c1O -US20100041892A1,2,CCCCCS(N)(=O)=O.COCCCOc1ccc(CCC(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1>>CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl -US20080293716A1,2,Cc1ccc(CCN)cc1.O=C(O)c1ccc(-c2ccncc2)s1>>Cc1ccc(CCNC(=O)c2ccc(-c3ccncc3)s2)cc1 -US20090023789A1,2,CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)C1CCNC1.CCOC(=O)Cl>>CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)C1CCN(C(=O)OCC)C1 -US06919371B2,7,CC(C)(C)OC(=O)N(C[C@H]1CCc2cc([N+](=O)[O-])ccc2O1)C[C@H](O)c1cccnc1>>CC(C)(C)OC(=O)N(C[C@H]1CCc2cc(N)ccc2O1)C[C@H](O)c1cccnc1 -US20100121048A1,6,COC(=O)c1ncn(C2CCCN(C(=O)OCc3ccccc3)C2)c1-c1ccccc1>>O=C(O)c1ncn(C2CCCN(C(=O)OCc3ccccc3)C2)c1-c1ccccc1 -US20100266504A1,1,CC(C)(C)OC(=O)N1CCc2nc(Cl)ccc2C1.C[C@@H]1COCCN1>>C[C@@H]1COCCN1c1ccc2c(n1)CCN(C(=O)OC(C)(C)C)C2 -US20080293782A1,2,CC(=O)Cl.Cc1cc(N)c(O)cc1C>>CC(=O)Nc1cc(C)c(C)cc1O -US20080261941A1,6,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cc3)c2)CC1>>FC(F)(F)c1ccc(Oc2cccc(C=C3CCNCC3)c2)cc1 -US04228284,1,N#Cc1cccc2c1CC(=O)c1ccccc1S2.NN>>N#Cc1cccc2c1CC(=NN)c1ccccc1S2 -US07173043B2,1,C1CNC1.Fc1ccc(-c2csc3cc(OCCCBr)ccc23)cc1>>Fc1ccc(-c2csc3cc(OCCCN4CCC4)ccc23)cc1 -US08476255B2,2,COC(=O)CCCCCCN.O=C(O)/C(=C/c1ccccc1)c1ccccc1>>COC(=O)CCCCCCNC(=O)/C(=C/c1ccccc1)c1ccccc1 -US06943162B2,1,CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCNCC2)n1.ClCc1cccnc1>>CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCN(Cc3cccnc3)CC2)n1 -US20100075952A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CC(O)CN1CCOCC1)CCC2.O=C1Cc2cc(Br)ccc2N1>>Cc1c(C=C2C(=O)Nc3ccc(Br)cc32)[nH]c2c1C(=O)N(CC(O)CN1CCOCC1)CCC2 -US20050032868A1,6,COC(=O)c1cc(NC(=O)c2ccccc2Cl)[nH]n1>>O=C(O)c1cc(NC(=O)c2ccccc2Cl)[nH]n1 -US20070021454A1,1,C#CC(C)(C)Cl.COC(=O)c1ccccc1N>>C#CC(C)(C)Nc1ccccc1C(=O)OC -US04355031,1,BrC(c1ccccc1)c1ccccc1.C1CNCCN1>>c1ccc(C(c2ccccc2)N2CCNCC2)cc1 -US05665763,7,COC(=O)CCc1ccc(C)o1>>Cc1ccc(CCCO)o1 -US20120238575A1,9,CCc1nc(Cl)cc(-c2ccccc2OC)n1.NN>>CCc1nc(NN)cc(-c2ccccc2OC)n1 -US07504408B2,3,C#CCC(C)OC.COc1cc2c(Nc3c(Cl)cc(I)c4c3OCO4)ncnc2cc1OCCCN1CCN(C)C(=O)C1>>COc1cc2c(Nc3c(Cl)cc(C#CCC(C)OC)c4c3OCO4)ncnc2cc1OCCCN1CCN(C)C(=O)C1 -US07060109B2,6,CCCCOC(=O)c1sc2ccc(OCOC)cc2c1OC(=O)C(C)(C)C>>CCCCOC(=O)c1sc2ccc(O)cc2c1OC(=O)C(C)(C)C -US06689806B1,7,CC(=O)Nc1ccc2c(c1)NC(=O)C2=Cc1ccc(OCCN2CCOCC2)c(C2CCCCC2)c1>>CC(=O)Nc1ccc2c(c1)NC(=O)C2Cc1ccc(OCCN2CCOCC2)c(C2CCCCC2)c1 -US20030134748A1,6,CCOC(=O)c1sc(Br)c(Br)c1Cl>>O=C(O)c1sc(Br)c(Br)c1Cl -US07649001B2,1,N#Cc1ccc(F)c2ccccc12.OC1CCNCC1>>N#Cc1ccc(N2CCC(O)CC2)c2ccccc12 -US07326791B2,2,Nc1ccc(C(=O)N2CC=CC2)c(Cl)c1.O=C(O)Cc1cc2cc(Cl)ccc2[nH]1>>O=C(Cc1cc2cc(Cl)ccc2[nH]1)Nc1ccc(C(=O)N2CC=CC2)c(Cl)c1 -US20070259888A1,2,CC(C)C(=O)NCc1ccc(C(=O)O)cc1.CCOC[C@@H]1CCCN(C[C@H]2CCCC[C@@H]2N)C1>>CCOC[C@@H]1CCCN(C[C@H]2CCCC[C@@H]2NC(=O)c2ccc(CNC(=O)C(C)C)cc2)C1 -US05998415,6,CC(C)(C)OC(=O)NCCN(CCCc1c[nH]c2ccc(-n3cnnc3)cc12)Cc1ccccc1>>NCCN(CCCc1c[nH]c2ccc(-n3cnnc3)cc12)Cc1ccccc1 -US20080039437A1,2,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1C(F)F.Cc1ccc(F)c(CS(N)(=O)=O)c1>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3cc(C)ccc3F)CC2)nc1C(F)F -US20110071150A1,4,CC(=O)c1ccc(OC(F)(F)F)cc1.NNc1ccc(Br)cc1>>FC(F)(F)Oc1ccc(-c2cc3cc(Br)ccc3[nH]2)cc1 -US04569941,7,COc1ccc(CCC2(CCC(Cc3ccc(OC)c(OC)c3)[N+](=O)[O-])OCCO2)cc1>>COc1ccc(CCC2(CCC(N)Cc3ccc(OC)c(OC)c3)OCCO2)cc1 -US07858781B2,2,COc1ccc(-c2cccc3[nH]c(C(=O)O)cc23)cc1.C[C@@H](CN1CCC(N)CC1)N1CCC(O)CC1>>COc1ccc(-c2cccc3[nH]c(C(=O)NC4CCN(C[C@H](C)N5CCC(O)CC5)CC4)cc23)cc1 -US20150183801A1,3,CC1(C)OB(c2cncc(C#N)c2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1>>N#Cc1cncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)c1 -US20140275007A1,6,CC(C)(C)OC(=O)N[C@@H]1C(=O)N(O)C1(C)C>>CC1(C)[C@H](N)C(=O)N1O -US20090012076A1,1,COc1ccc(CN)c(OC)c1.O=Cc1csnn1>>COc1ccc(CNCc2csnn2)c(OC)c1 -US07087606B2,6,COc1ccc(-c2cc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(=O)n(CC3CC3)n2)cc1F>>COc1ccc(-c2cc(CN3CCNCC3)c(=O)n(CC3CC3)n2)cc1F -US08604029B2,2,CC(C)(C(=O)O)c1ccc([N+](=O)[O-])cc1.OCCBr>>CC(C)(C(=O)OCCBr)c1ccc([N+](=O)[O-])cc1 -US04762932,1,NC(=NCC(F)(F)F)Nc1cncc(Cl)n1.NCCS>>NCCSc1cncc(NC(N)=NCC(F)(F)F)n1 -US20110217311A1,1,CN(C(=O)OC(C)(C)C)C1CCCC(O)C1.O=[N+]([O-])c1ccc(F)cc1F>>CN(C(=O)OC(C)(C)C)C1CCCC(Oc2cc(F)ccc2[N+](=O)[O-])C1 -US20110092505A1,3,CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(Br)n2)CC1.OB(O)c1ccnc(F)c1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(-c3ccnc(F)c3)n2)CC1 -US20050107389A1,6,CC(C)(C)OC(=O)N1CCC(c2noc3c(C(F)(F)F)cccc23)CC1>>FC(F)(F)c1cccc2c(C3CCNCC3)noc12 -US20050009820A1,6,CCC1CCc2c(sc3cc(OC)ccc3c2=O)C1>>CCC1CCc2c(sc3cc(O)ccc3c2=O)C1 -US20110144334A1,2,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)Cl.Nc1ncc(Cl)cn1>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)Nc1ncc(Cl)cn1 -US20140336208A1,1,CN1C(=O)C(C)(C)[C@@](C)(c2cc(N)ccc2F)N=C1N.O=C(O)c1cccc2c1CCC2=O>>CN1C(=O)C(C)(C)[C@@](C)(c2cc(NC3CCc4c(C(=O)O)cccc43)ccc2F)N=C1N -US20140135316A1,1,Cc1nnc2n1-c1c(F)cccc1NCC2.Clc1ccc(I)cc1>>Cc1nnc2n1-c1c(F)cccc1N(c1ccc(Cl)cc1)CC2 -US20090163494A1,3,COC(=O)C(C(=O)OC)c1ccc(Br)cc1[N+](=O)[O-].COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O>>COC(=O)C(C(=O)OC)c1ccc(-c2ccc(O)c(OC)c2)cc1[N+](=O)[O-] -US20140088074A1,6,CCCCOc1cccc(C(F)(F)CN(C(=O)OC(C)(C)C)C(C)C(=O)N(C)C)c1>>CCCCOc1cccc(C(F)(F)CNC(C)C(=O)N(C)C)c1 -US05523424,9,ClCC1(COc2ccccc2)COC1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC1(COc2ccccc2)COC1 -US06025370,1,COC(=O)c1ccc(F)c(O)c1F.FC(F)Cl>>COC(=O)c1ccc(F)c(OC(F)F)c1F -US20150238500A1,2,COCCn1ccc(-c2ccsc2)c1C(=O)C(=O)O.Cc1cc(C)nc(N2CCN(c3ccc(N)cc3)CC2)c1>>COCCn1ccc(-c2ccsc2)c1C(=O)C(=O)Nc1ccc(N2CCN(c3cc(C)cc(C)n3)CC2)cc1 -US20120029023A1,1,Brc1ccc(Br)nc1.Oc1ccccc1>>Brc1ccc(Oc2ccccc2)nc1 -US06479519B1,6,COC(=O)C[C@@H](NC(=O)c1ccccc1)c1ccc(N(C(C)=O)c2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)cc1>>COc1cc(N(C(C)=O)c2ccc([C@@H](CC(=O)O)NC(=O)c3ccccc3)cc2)ccc1NC(=O)Nc1ccccc1C -US20080312282A1,3,CC1(C)OB(c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)nc2)OC1(C)C.O=C(O)COC1(c2ccc(Br)cc2F)CCC1>>O=C(O)COC1(c2ccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)nc3)cc2F)CCC1 -US08138181B2,1,CN1CCC(CO)C1.COCCOc1ccn2c(-c3ccc4cccc(O)c4n3)cnc2c1>>COCCOc1ccn2c(-c3ccc4cccc(OCC5CCN(C)C5)c4n3)cnc2c1 -US08674113B2,7,CNc1cc(N2CCC(F)(F)C2)c(C(=O)OC)cc1[N+](=O)[O-]>>CNc1cc(N2CCC(F)(F)C2)c(C(=O)OC)cc1N -US07230020B2,2,Nc1ccc2c(c1)CCC2=O.O=C(O)c1cc(Cl)ccc1Cl>>O=C(Nc1ccc2c(c1)CCC2=O)c1cc(Cl)ccc1Cl -US20100286390A1,6,C[C@H]1[C@H](Nc2cnn(CC(=O)NCC(=O)OC(C)(C)C)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C>>C[C@H]1[C@H](Nc2cnn(CC(=O)NCC(=O)O)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C -US20150224105A1,1,CC(C)N.Fc1cc(F)c(-c2c(Cl)nc3nccnc3c2Cl)c(F)c1>>CC(C)Nc1nc2nccnc2c(Cl)c1-c1c(F)cc(F)cc1F -US06506775B1,1,N[C@H]1CCCN[C@H]1c1ccccc1.O=Cc1cc(C(F)(F)F)ccc1Oc1ccccc1>>FC(F)(F)c1ccc(Oc2ccccc2)c(CN[C@H]2CCCN[C@H]2c2ccccc2)c1 -US08492378B2,3,COC(=O)c1ccc2ncc(I)n2c1.COc1ccc(B(O)O)cc1>>COC(=O)c1ccc2ncc(-c3ccc(OC)cc3)n2c1 -US20100036118A1,2,CNC.O=C(O)c1cc(Br)ccc1I>>CN(C)C(=O)c1cc(Br)ccc1I -US20150183802A1,7,CNc1cc(C#N)c(F)cc1[N+](=O)[O-]>>CNc1cc(C#N)c(F)cc1N -US08642621B2,6,CC(C)(C)OC(=O)N1CC=C(c2ccccc2[N+](=O)[O-])CC1>>O=[N+]([O-])c1ccccc1C1=CCNCC1 -US20110124618A1,6,CCOC(=O)c1cc(-c2cccc(Cl)c2)n(-c2cccc(C(F)(F)F)c2)n1>>O=C(O)c1cc(-c2cccc(Cl)c2)n(-c2cccc(C(F)(F)F)c2)n1 -US06506755B2,3,O=C1CSC(=S)N1.O=Cc1cc(OCc2ccccc2)ccc1OCc1ccccc1>>O=C1NC(=S)SC1=Cc1cc(OCc2ccccc2)ccc1OCc1ccccc1 -US20140163009A1,1,CN1CCNCC1.COC(=O)[C@H]1[C@H](c2ccc(Br)cc2)[C@H]1c1ccccc1>>COC(=O)[C@H]1[C@H](c2ccc(N3CCN(C)CC3)cc2)[C@H]1c1ccccc1 -US20100112090A1,1,COc1cc(Cl)c([N+](=O)[O-])cc1O.COc1cccc(F)c1CBr>>COc1cc(Cl)c([N+](=O)[O-])cc1OCc1c(F)cccc1OC -US06498151B2,1,CC(C)CCBr.CCOC(=O)c1cc(I)ccc1O>>CCOC(=O)c1cc(I)ccc1OCCC(C)C -US20110237618A1,1,C/C=C1\[C@H]2C=C(C)C[C@@]1(N)c1ccc(=O)[nH]c1C2.C=O>>C/C=C1\[C@H]2C=C(C)C[C@]1(NC)c1ccc(=O)[nH]c1C2 -US20060142312A1,2,CS(=O)(=O)Cl.O=c1c(Cc2ccccn2)cc2cnc(NC3CCNCC3)nc2n1C1CCCC1>>CS(=O)(=O)N1CCC(Nc2ncc3cc(Cc4ccccn4)c(=O)n(C4CCCC4)c3n2)CC1 -US08003662B2,2,CCOC(=O)C(=O)Nc1ccc(Oc2ccnc3ccsc23)c(F)c1.NCCN1CCOCC1>>O=C(NCCN1CCOCC1)C(=O)Nc1ccc(Oc2ccnc3ccsc23)c(F)c1 -US05082934,10,Cc1ccc2ccc(=O)oc2c1.O=C1CCC(=O)N1Br>>O=c1ccc2ccc(CBr)cc2o1 -US20060257987A1,2,CCCc1c(OC(CCC)CCO)ccc2c(-c3ccccc3)noc12.CS(=O)(=O)Cl>>CCCc1c(OC(CCC)CCOS(C)(=O)=O)ccc2c(-c3ccccc3)noc12 -US04331820,7,CCCCC#CCCO>>CCCC/C=C\CCO -US20120059028A1,6,C#CCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCCC3>>C#CCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCCC3 -US07816386B2,6,COC(=O)/C=C/c1ccc2[nH]ccc2c1>>O=C(O)/C=C/c1ccc2[nH]ccc2c1 -US20110201640A1,4,CCCc1nc2ccccc2n1Cc1ccc2c(c1)CCc1ccccc1/C2=C\C#N.C[Si](C)(C)N=[N+]=[N-]>>CCCc1nc2ccccc2n1Cc1ccc2c(c1)CCc1ccccc1/C2=C\c1nnn[nH]1 -US20120316147A1,6,CCOC(=O)[C@H](CC(C)C)NC(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1>>CC(C)C[C@H](NC(=O)c1ccc(C2CC2)c(Cc2ccc(F)cc2)n1)C(=O)O -US08778936B2,1,CN1CCNCC1.N#Cc1cc(F)cc(Cl)c1>>CN1CCN(c2cc(Cl)cc(C#N)c2)CC1 -US06458337B1,2,N[C@@H](CCC(=O)O)C(=O)O.O=C(Cl)OCc1ccccc1>>O=C(O)CC[C@H](NC(=O)OCc1ccccc1)C(=O)O -US20080139530A1,2,CC(O)(c1ccsc1)c1cc(Br)ccc1N.O=C(Cl)CCl>>CC(O)(c1ccsc1)c1cc(Br)ccc1NC(=O)CCl -US20080293712A1,1,CC(C)(C)OC(=O)N[C@H](CO)Cc1ccccc1Cl.COC(=O)c1cncc(O)c1>>COC(=O)c1cncc(OC[C@H](Cc2ccccc2Cl)NC(=O)OC(C)(C)C)c1 -US20050113346A1,1,CC#CCOc1ccc(S(=O)(=O)NC)cc1.COC(=O)C(Br)c1ccc(Cl)cc1>>CC#CCOc1ccc(S(=O)(=O)N(C)C(C(=O)OC)c2ccc(Cl)cc2)cc1 -US20070249670A1,7,COc1ccc(-c2ccc(C(=O)O)c([N+](=O)[O-])c2)cc1>>COc1ccc(-c2ccc(C(=O)O)c(N)c2)cc1 -US04570006,2,O=C(Cl)c1ccccc1.Oc1ccc(Br)cc1>>O=C(Oc1ccc(Br)cc1)c1ccccc1 -US20150272947A1,4,CCOC(=O)C(C)(C(=O)OCC)c1ccc(N)cc1.ClCCNCCCl>>CCOC(=O)C(C)(C(=O)OCC)c1ccc(N2CCNCC2)cc1 -US20140194430A1,1,CNCC(O)c1ccccc1.Clc1ccc2ncc(-c3cc4cnccc4o3)n2n1>>CN(CC(O)c1ccccc1)c1ccc2ncc(-c3cc4cnccc4o3)n2n1 -US09156827B2,3,COc1ccc2c(c1CCCCN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.O=Cc1n[nH]c2ccccc12>>COc1ccc2c(c1CCCCN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O -US06355813B1,7,CCCOc1ccc2c(c1)C(=O)C=C2c1ccc2c(c1)OCO2>>CCCOc1ccc2c(c1)C(=O)C[C@H]2c1ccc2c(c1)OCO2 -US04654369,2,CNC.COC(=O)c1c([N+](=O)[O-])cccc1S(=O)(=O)NCCO>>CN(C)C(=O)c1c([N+](=O)[O-])cccc1S(=O)(=O)NCCO -US20100173941A1,1,CC(C)OCCOCCCl.O=c1[nH]c2ccccc2n1C1CCNCC1>>CC(C)OCCOCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1 -US20060063779A1,2,Nc1ccc(Cl)c(-c2ccccn2)c1.O=C(O)c1ccc(S(=O)(=O)NCC(F)(F)F)cc1>>O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(S(=O)(=O)NCC(F)(F)F)cc1 -US20040072818A1,2,CC(C)(C)OC(=O)N[C@@H]1CCCCN(C(=O)C(C)(C)C)C1=O.Nc1cc(N2CCNCC2)c2ccc(Cl)cc2n1>>CC(C)(C)C(=O)N1CCCC[C@H](NC(=O)N2CCN(c3cc(N)nc4cc(Cl)ccc34)CC2)C1=O -US07642267B2,4,C#CC(=O)OCC.CCn1c(Cn2ccnc2-c2cc(F)ccc2F)nc2cc(N=[N+]=[N-])ccc21>>CCOC(=O)c1cn(-c2ccc3c(c2)nc(Cn2ccnc2-c2cc(F)ccc2F)n3CC)nn1 -US04125732,10,COC(=O)Cc1ccc(OCOc2ccc(Cl)cc2)cc1.O=C1CCC(=O)N1Br>>COC(=O)C(Br)c1ccc(OCOc2ccc(Cl)cc2)cc1 -US09149465B2,1,BrC1=NOCC1.Oc1cncnc1>>c1ncc(OC2=NOCC2)cn1 -US05480790,2,C=CC(=O)Cl.NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>C=CC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO -US05591762,6,CCCCc1nc2c(C)cc(NC(=O)C(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2c(C)cc(NC(=O)C(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20140088046A1,2,CS(=O)(=O)Cc1cc(-c2ccc([C@@H](O)[C@H](N)CF)cc2)on1.O=C(Cl)C(F)F>>CS(=O)(=O)Cc1cc(-c2ccc([C@@H](O)[C@@H](CF)NC(=O)C(F)F)cc2)on1 -US20030083326A1,7,COC(=O)c1cc(OC)c2c(c1)OCO2>>COc1cc(CO)cc2c1OCO2 -US20130116288A1,6,COc1ccc(COc2ccc(-c3nnc([C@H](Nc4ccc(C#N)c(Cl)c4C)[C@H](C)O[Si](C)(C)C(C)(C)C)o3)cc2)cc1>>Cc1c(N[C@@H](c2nnc(-c3ccc(O)cc3)o2)[C@H](C)O[Si](C)(C)C(C)(C)C)ccc(C#N)c1Cl -US20080027035A1,2,CC(C)(C)OC(=O)NC(CC(=O)N1CCCC1CN)Cc1ccccc1F.COc1ccc(S(=O)(=O)Cl)cc1OC>>COc1ccc(S(=O)(=O)NCC2CCCN2C(=O)CC(Cc2ccccc2F)NC(=O)OC(C)(C)C)cc1OC -US20110257198A1,3,C=C[Sn](CCCC)(CCCC)CCCC.Cc1ccc(-c2ncc(C)o2)c(Cl)n1>>C=Cc1nc(C)ccc1-c1ncc(C)o1 -US20110043746A1,1,CCBr.C[Si](C)(C)c1cc2ccc(F)c(F)c2cc1O>>CCOc1cc2c(F)c(F)ccc2cc1[Si](C)(C)C -US07902367B2,1,CC(C)(C)OC(=O)N1CCCC(CO)C1.Oc1ccc(-c2ccc(Cl)cc2)cc1>>CC(C)(C)OC(=O)N1CCCC(COc2ccc(-c3ccc(Cl)cc3)cc2)C1 -US20110071147A1,6,COC1CCN(CCCCNC(=O)OCc2ccccc2)CC1>>COC1CCN(CCCCN)CC1 -US06303783B1,7,Cn1c(C(F)(F)F)cc(=O)n(-c2cc([N+](=O)[O-])c(Cl)cc2F)c1=O>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(N)c(Cl)cc2F)c1=O -US20080090854A1,6,COC(=O)C(C)(C)NC(=O)c1ccc2ccccc2c1OC(C)c1nc2ccccc2s1>>CC(Oc1c(C(=O)NC(C)(C)C(=O)O)ccc2ccccc12)c1nc2ccccc2s1 -US08048909B2,4,CN(Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cccc(C#N)c2)c1)C(=O)OC(C)(C)C.[N-]=[N+]=[N-]>>CN(Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cccc(-c3nnn[nH]3)c2)c1)C(=O)OC(C)(C)C -US08513186B2,7,COc1cccc([N+](=O)[O-])c1C>>COc1cccc(N)c1C -US08829026B2,1,CCc1cc(C(=O)OC)ccc1S(=O)(=O)NCc1ccc2c(cnn2C)c1.FC(F)(F)c1cnc(Cl)c(Cl)c1>>CCc1cc(C(=O)OC)ccc1S(=O)(=O)N(Cc1ccc2c(cnn2C)c1)c1ncc(C(F)(F)F)cc1Cl -US20100004292A1,7,N#Cc1ccc(C(=O)O)c([N+](=O)[O-])c1>>N#Cc1ccc(C(=O)O)c(N)c1 -US08415379B2,2,CC(C)(N)CO.Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)O)nc1>>Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)NC(C)(C)CO)nc1 -US20140323562A1,8,O=C(OO)c1cccc(Cl)c1.c1coc(CSSCc2ccco2)c1>>O=S(Cc1ccco1)SCc1ccco1 -US08426420B2,1,CI.O=C(N[C@@H](CCCCO)C(=O)N1CCN(C(=O)OC2CCC2)CC1)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1>>CN(C(=O)[C@@H]1CCCN1C(=O)COc1cc(C(=O)N[C@@H](CCCCO)C(=O)N2CCN(C(=O)OC3CCC3)CC2)nn1-c1ccccc1)C1CCC1 -US08466143B2,2,CCOC(=O)c1cc2c(n1C)C(C(=O)OC(C)C)=CNCC2(C)C.O=C(Cl)c1ccc(F)c(F)c1>>CCOC(=O)c1cc2c(n1C)C(C(=O)OC(C)C)=CN(C(=O)c1ccc(F)c(F)c1)CC2(C)C -US05202437,2,CS(=O)(=O)Cl.O=C1NCCN1C[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1>>CS(=O)(=O)O[C@@H]1C[C@@H](CN2CCNC2=O)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1 -US08426411B2,2,C1COCCN1.CS(=O)(=O)Cl>>CS(=O)(=O)N1CCOCC1 -US05709911,3,CCOC(=O)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C[C@@H]1CC[C@@H](c2cccc(F)c2F)CC1>>CCOC(=O)CCC=C[C@@H]1CC[C@@H](c2cccc(F)c2F)CC1 -US20130029962A1,2,Nc1ccc(N2CC[C@@H](O)C2)nc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(N2CC[C@@H](O)C2)nc1)Oc1ccccc1 -US05059608,1,CC1(c2ccccc2)NCCc2ccccc21.CI>>CN1CCc2ccccc2C1(C)c1ccccc1 -US06713474B2,2,CS(=O)(=O)Cl.OC1CCN2CCCC12>>CS(=O)(=O)OC1CCN2CCCC12 -US04340600,1,C=O.COc1ccccc1CNCC(O)c1ccc(OC)c(OC)c1>>COc1ccccc1CN(C)CC(O)c1ccc(OC)c(OC)c1 -US05977111,9,NO.O=C1CC(CCCN2CCN(c3ccc(F)cc3)CC2)S(=O)(=O)c2ccccc21>>O=S1(=O)c2ccccc2C(=NO)CC1CCCN1CCN(c2ccc(F)cc2)CC1 -US07253198B2,6,CCN(Cc1ccc(OC)cc1)c1cc(C(=O)OC)c(F)c(N2CCCC2=O)c1>>CCNc1cc(C(=O)OC)c(F)c(N2CCCC2=O)c1 -US04838924,1,CC1=CC(C)(C)c2ccc(Oc3ccc([N+](=O)[O-])cc3)cc2O1.CO>>COC1(C)CC(C)(C)c2ccc(Oc3ccc([N+](=O)[O-])cc3)cc2O1 -US04002746,2,CC[C@]12CC[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2O.O=C(Cl)CCc1ccccc1>>CC[C@]12CC[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2OC(=O)CCc1ccccc1 -US20110218103A1,4,NC(=O)c1cc(Cl)cc(N)c1N.O=C(O)C(F)(F)F>>NC(=O)c1cc(Cl)cc2[nH]c(C(F)(F)F)nc12 -US04119727,1,CCOC(=O)CBr.CCOC(=O)c1sc(Cl)cc1O>>CCOC(=O)COc1cc(Cl)sc1C(=O)OCC -US20150218170A1,3,C#C[Si](C)(C)C.Cc1nc(N)c(Br)nc1Br>>Cc1nc(N)c(C#C[Si](C)(C)C)nc1Br -US20090111828A1,6,COC(=O)[C@H](Cc1ccc(Br)cn1)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](N)Cc1ccc(Br)cn1 -US05912273,1,BrCCOCc1ccccc1.OCCC(=C(c1ccc(O)cc1)c1ccc(OCc2ccccc2)cc1)c1ccccc1>>OCC/C(=C(/c1ccc(OCCOCc2ccccc2)cc1)c1ccc(OCc2ccccc2)cc1)c1ccccc1 -US08327467B2,6,COC(=O)c1ccc(CSc2ccccc2)cc1Nc1ccc(F)cc1>>O=C(O)c1ccc(CSc2ccccc2)cc1Nc1ccc(F)cc1 -US07229987B2,7,CN(C)CCCOc1ccc([N+](=O)[O-])cc1>>CN(C)CCCOc1ccc(N)cc1 -US06103718,1,CCBr.COc1ccc(C2=NNC(=O)[C@H]3CCCC[C@@H]23)cc1OC>>CCN1N=C(c2ccc(OC)c(OC)c2)[C@@H]2CCCC[C@@H]2C1=O -US20060223801A1,1,NC(=O)c1cc(Cl)nc(Cl)c1.OC1CCNCC1>>NC(=O)c1cc(Cl)nc(N2CCC(O)CC2)c1 -US04347365,6,COC(=O)c1nc(-c2ccccn2)n2c1CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2>>O=C(O)c1nc(-c2ccccn2)n2c1CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2 -US05155268,6,CS(=O)(=O)Nc1ccc(CCC(=O)OCc2ccccc2)cc1>>CS(=O)(=O)Nc1ccc(CCC(=O)O)cc1 -US07241787B2,1,CCOC(CBr)OCC.Nc1ccc(OC2CCCC2)cc1>>CCOC(CNc1ccc(OC2CCCC2)cc1)OCC -US20050014812A1,3,CCCCCOc1ccc(Cn2c(OCC)nc3c(C)cc(Br)cc32)c(Cl)c1.O=C(O)c1ccc(B(O)O)cc1>>CCCCCOc1ccc(Cn2c(OCC)nc3c(C)cc(-c4ccc(C(=O)O)cc4)cc32)c(Cl)c1 -US04539150,2,Nc1ccccc1SC(c1ccccc1)[C@H](NC(=O)OCc1ccccc1)C(=O)O>>O=C(NC1C(=O)Nc2ccccc2SC1c1ccccc1)OCc1ccccc1 -US05420132,7,O=C(C1=COc2cc(O)ccc2O1)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1>>Oc1ccc2c(c1)OC=C(CN1CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC1)O2 -US20120190684A1,1,Fc1nc(F)c(Cl)c(F)c1F.OCC(F)(F)F>>Fc1nc(F)c(Cl)c(OCC(F)(F)F)c1F -US20120009274A1,1,Cc1cccc(C(=O)NN)c1.O=Cc1cccc(Cl)c1O>>Cc1cccc(C(=O)NN=Cc2cccc(Cl)c2O)c1 -US08518956B2,1,CCOCCn1nc(CC)c2nc(Cl)nc(Nc3cc(C)ccn3)c21.O=C(O)C1CCNCC1>>CCOCCn1nc(CC)c2nc(N3CCC(C(=O)O)CC3)nc(Nc3cc(C)ccn3)c21 -US06194406B1,2,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.COc1ccc(-c2nnn[nH]2)cc1C(=O)O>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(-c5nnn[nH]5)ccc4OC)C3)CC2)nc2ccccc21 -US08153644B2,2,O=C(Nc1ccc(C2CCNCC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F.O=C(O)CCc1cc(O)no1>>O=C(Nc1ccc(C2CCN(C(=O)CCc3cc(O)no3)CC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US08748421B2,2,Nc1ccc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cc1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)Nc1ccc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cc1 -US06495546B1,1,CC(C)(C)OC(=O)N(Cc1ccccc1)C1CCCc2ccc(O)cc2C1.COCCCl>>COCCOc1ccc2c(c1)CC(N(Cc1ccccc1)C(=O)OC(C)(C)C)CCC2 -US08513415B2,1,NC(c1ccccc1)c1ccccc1.O=Cc1ccc2ccc(-c3ccccc3)nc2c1>>C(=N/C(c1ccccc1)c1ccccc1)\c1ccc2ccc(-c3ccccc3)nc2c1 -US07932390B2,6,COCOc1cc(-c2cn(C)nn2)ccc1C>>Cc1ccc(-c2cn(C)nn2)cc1O -US20080293768A1,3,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2cnccc2Br)SC[C@H]1OC(C)=O.OB(O)c1ccc(C(F)(F)F)cc1>>CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2cnccc2-c2ccc(C(F)(F)F)cc2)SC[C@H]1OC(C)=O -US04086234,1,C1CCNCC1.CCC(C#N)(CCCl)c1ccccc1>>CCC(C#N)(CCN1CCCCC1)c1ccccc1 -US06071901,1,CCOC(=O)C1CCCCN1.ClCCCN1c2ccccc2CCc2ccccc21>>CCOC(=O)C1CCCCN1CCCN1c2ccccc2CCc2ccccc21 -US20100022572A1,2,C1=CC2(CCNCC2)c2ccccc21.O=C(Br)CBr>>O=C(CBr)N1CCC2(C=Cc3ccccc32)CC1 -US20110306587A1,6,COc1ccc(-c2nccnc2C2CN(C(=O)OC(C)(C)C)C2)cc1>>COc1ccc(-c2nccnc2C2CNC2)cc1 -US06060484,7,Cc1cccc([N+](=O)[O-])c1Cl>>Cc1cccc(N)c1Cl -US08415355B2,1,CC(Br)CO.CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CCCC1>>CC(CO)N1CCN(c2ccc(Nc3ncc4cc(C(=O)N(C)C)n(C5CCCC5)c4n3)nc2)CC1 -US08591878B2,6,C=CCn1cc(C)c2c3ccccc3nc(O[C@@H]3C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C3)c21>>C=CCn1cc(C)c2c3ccccc3nc(O[C@H]3CN[C@H](C(=O)OC)C3)c21 -US20150203492A1,2,C=CC[C@H](NC(=O)OC(C)(C)C)c1cc(-c2ccc(N)cc2N)ccn1.COC(=O)Cl>>C=CC[C@H](NC(=O)OC(C)(C)C)c1cc(-c2ccc(NC(=O)OC)cc2N)ccn1 -US20100010053A1,1,CC(C)Oc1ccc(-c2nc(-c3cccc4c(CC=O)cn(C)c34)no2)cc1Cl.O=C(O)C1CNC1>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCN5CC(C(=O)O)C5)cn(C)c34)no2)cc1Cl -US20040121965A1,6,C/C(=C\[C@H](C(C)C)N(C)C(=O)[C@H](CCc1ccccc1)NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1)C(=O)O>>CN[C@H](C(=O)N[C@@H](CCc1ccccc1)C(=O)N(C)[C@H](/C=C(\C)C(=O)O)C(C)C)C(C)(C)c1ccccc1 -US20070043065A1,1,CS(=O)(=O)N1CCNCC1.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cc(F)ccc1[N+](=O)[O-]>>Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cc(N2CCN(S(C)(=O)=O)CC2)ccc1[N+](=O)[O-] -US20140081025A1,1,CI.O=C(NCCc1noc(-c2ccc(F)cc2)n1)c1ccccc1-n1nccn1>>CN(CCc1noc(-c2ccc(F)cc2)n1)C(=O)c1ccccc1-n1nccn1 -US05064861,1,CCC(C)c1ccc(C(F)(F)F)cc1O.CCOC(=O)CBr>>CCOC(=O)COc1cc(C(F)(F)F)ccc1C(C)CC -US04555365,9,CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)CC(=O)O.N>>CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)CC(N)=O -US05036086,6,CC(=O)OCC(=O)Nc1nc2cc(C)c(C)cc2s1>>Cc1cc2nc(NC(=O)CO)sc2cc1C -US20090291978A1,6,CC(C)(C)OC(=O)N(CC1c2[nH]c3ccccc3c2CCN1C(=O)OCc1ccccc1)[C@H](C(=O)OC1CCCC1)c1ccccc1>>CC(C)(C)OC(=O)N(CC1NCCc2c1[nH]c1ccccc21)[C@H](C(=O)OC1CCCC1)c1ccccc1 -US03940444,10,CCC(=O)C=C(C)C=CCC(C)CCC=C(C)C.O>>CCC(=O)C=C(C)C=CCC(C)CCCC(C)(C)O -US08404676B2,3,COC(=O)c1ccc(Br)c(C)c1.OB(O)c1ccccc1C(F)(F)F>>COC(=O)c1ccc(-c2ccccc2C(F)(F)F)c(C)c1 -US20030073840A1,7,CCOC(=O)C=C(CC)c1cc([Si](C)(C)C)nc(OC)c1COCOC>>CCC(=CCO)c1cc([Si](C)(C)C)nc(OC)c1COCOC -US20090264445A1,6,COCC[C@@H](C(=O)OC)N1CC(Oc2ccccc2Cl)=CC1=O>>COCC[C@@H](C(=O)O)N1CC(Oc2ccccc2Cl)=CC1=O -US20070155805A1,6,CCCCC(CCOc1ccc(OCC(=O)OCC)c(CC)c1)c1sc2cc(C(F)(F)F)ccc2c1C>>CCCCC(CCOc1ccc(OCC(=O)O)c(CC)c1)c1sc2cc(C(F)(F)F)ccc2c1C -US08399674B2,1,CC1(C)Cc2cccc(Nc3ccc4cc(Br)ccc4n3)c2O1.Cc1cccc(N)n1>>Cc1cccc(Nc2ccc3nc(Nc4cccc5c4OC(C)(C)C5)ccc3c2)n1 -US20130172339A1,2,COc1ccc2sc(S(=O)(=O)Cl)c(C)c2c1.Nc1cccc(-c2nnn[nH]2)c1>>COc1ccc2sc(S(=O)(=O)Nc3cccc(-c4nnn[nH]4)c3)c(C)c2c1 -US08637525B2,1,FC1=CCNCC1.Fc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1>>FC1=CCN(c2nc(Cl)nc3c2CCC3c2ccc(F)cc2)CC1 -US06407129B1,2,O=C(Cl)OCCl.OCCCOCc1ccccc1>>O=C(OCCl)OCCCOCc1ccccc1 -US07393868B2,2,CN.O=C(O)CCc1ccc(Br)cc1>>CNC(=O)CCc1ccc(Br)cc1 -US20040102636A1,2,C1COCCN1.O=C(Br)CBr>>O=C(CBr)N1CCOCC1 -US04956371,2,COC(=O)c1cc(OC)c(OC)c(OC)c1.Cc1cccc(CCN)c1>>COc1cc(C(=O)NCCc2cccc(C)c2)cc(OC)c1OC -US20130324551A1,9,COC(=O)C1CCOCC1.N>>NC(=O)C1CCOCC1 -US05962682,2,C1COCCN1.COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(C(=O)O)cc2OCCO)c1>>COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(C(=O)N3CCOCC3)cc2OCCO)c1 -US07273868B2,2,COc1ccc(CNc2nc(SC)nc(Cl)c2C(=O)Cl)cc1Cl.OCCOCc1ccccc1>>COc1ccc(CNc2nc(SC)nc(Cl)c2C(=O)OCCOCc2ccccc2)cc1Cl -US20090198063A1,1,CO.Cc1cc(=O)n(CCN2CCC(N(Cc3cc4c(cn3)OCCO4)C(=O)OC(C)(C)C)CC2)c2cc(F)cnc12>>COc1cnc2c(C)cc(=O)n(CCN3CCC(N(Cc4cc5c(cn4)OCCO5)C(=O)OC(C)(C)C)CC3)c2c1 -US07407977B2,2,N#Cc1ccc(C(=O)Cl)cc1.Nc1nc2c(s1)Cc1ccccc1-2>>N#Cc1ccc(C(=O)Nc2nc3c(s2)Cc2ccccc2-3)cc1 -US20050014023A1,3,Brc1ccccn1.OB(O)c1cc2ccccc2s1>>c1ccc(-c2cc3ccccc3s2)nc1 -US20030073836A1,2,NCc1ccc(N2CCCc3ccccc32)cc1.O=C(O)c1cc(Cl)ncn1>>O=C(NCc1ccc(N2CCCc3ccccc32)cc1)c1cc(Cl)ncn1 -US20040224939A1,6,CC(=O)NCC1CN(c2ccc3c(c2)CN(C(=O)OC(C)(C)C)CCO3)C(=O)O1>>CC(=O)NCC1CN(c2ccc3c(c2)CNCCO3)C(=O)O1 -US20100004238A1,1,Cn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2cccc3[nH]ncc23)c(Cl)c1>>Cn1ccc2ncnc(Nc3ccc(Oc4cccc5[nH]ncc45)c(Cl)c3)c21 -US04753941,2,Nc1ccc2ccc(Cl)nc2n1.O=C(O)c1cscn1>>O=C(Nc1ccc2ccc(Cl)nc2n1)c1cscn1 -US20030176710A1,3,CC1(C)OCC[C@@H](C(C)(C)C=O)O1.C[Mg+]>>CC(O)C(C)(C)[C@@H]1CCOC(C)(C)O1 -US06252086B1,3,C#CCCC(=O)OC.COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(Br)c21>>COC(=O)CCC#Cc1c([N+](=O)[O-])ccc2c1/C(=C/c1[nH]ccc1OC)C(=O)N2 -US20060025474A1,7,CCC(O)(C#Cc1ccc(C(CC)(CC)c2ccc(OC[C@@H](O)CCC(=O)O)c(C)c2)cc1C)CC>>CCC(O)(CC)CCc1ccc(C(CC)(CC)c2ccc(OC[C@@H](O)CCC(=O)O)c(C)c2)cc1C -US20110135670A1,1,CCCCOc1nc(N)c2nc(OC)n(CCCN)c2n1.O=CC1CCCOC1>>CCCCOc1nc(N)c2nc(OC)n(CCCNCC3CCCOC3)c2n1 -US20100041892A1,1,CCOC(=O)/C=C/c1cc(O)nn1Cc1ccc(Cl)cc1Cl.COCCO>>CCOC(=O)/C=C/c1cc(OCCOC)nn1Cc1ccc(Cl)cc1Cl -US20050250797A1,1,C#CCBr.OCC1CCCC1>>C#CCOCC1CCCC1 -US20020143020A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)SCc2ccc(OCc3ccc(F)cc3)cc2)CC1>>O=C(SCc1ccc(OCc2ccc(F)cc2)cc1)N1CCNCC1 -US06858638B2,6,CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc3[nH]nc(-c4ccccc4)c3c2)cc1>>Nc1ccc(S(=O)(=O)Nc2ccc3[nH]nc(-c4ccccc4)c3c2)cc1 -US05061718,6,CCCCC1(CCCC)CCc2c(OC)cccc2C1=O>>CCCCC1(CCCC)CCc2c(O)cccc2C1=O -US06689772B1,2,CCN1CCNCC1.O=C(O)Cc1ccc(I)cc1>>CCN1CCN(C(=O)Cc2ccc(I)cc2)CC1 -US04428955,1,Cc1cc(=O)c2ccc(O)cc2o1.O=C(NC1CCN(CCCCl)CC1)c1ccccc1>>Cc1cc(=O)c2ccc(OCCCN3CCC(NC(=O)c4ccccc4)CC3)cc2o1 -US20150080383A1,3,CON(C)C(=O)c1cc(=O)c2cc(Br)ccc2o1.C[Mg+]>>CC(=O)c1cc(=O)c2cc(Br)ccc2o1 -US20100063049A1,1,COC(=O)C1CCCC(N)C1.Cc1ncc(-c2ccnc(Cl)n2)n1C(C)C>>COC(=O)C1CCCC(Nc2nccc(-c3cnc(C)n3C(C)C)n2)C1 -US20120328569A1,3,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(Br)cc12.O=[N+]([O-])c1cccc(B(O)O)c1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cccc([N+](=O)[O-])c3)cc12 -US07834014B2,1,Nc1cc(Cl)nc2nc(-c3ccco3)nn12.OC[C@@H]1CC[C@H]2CNCCN2C1>>Nc1cc(N2CCN3CC(CO)CCC3C2)nc2nc(-c3ccco3)nn12 -US08134007B2,2,Nc1ccc(-c2cc(Cl)ccc2Cl)c(N)n1.O=C(O)c1cnon1>>Nc1nc(NC(=O)c2cnon2)ccc1-c1cc(Cl)ccc1Cl -US20060281772A1,1,O=[N+]([O-])c1ccc(Cl)nc1.OC1CCCC1>>O=[N+]([O-])c1ccc(OC2CCCC2)nc1 -US20130289072A1,1,CC(C)c1n[nH]c2cccc(-n3cnc(-c4cnn(C)c4)c3)c12.CCc1cc(C#N)ccc1F>>CCc1cc(C#N)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)cccc21 -US08232312B2,2,O=C=NCc1ccccc1.O=S(=O)(Nc1ccc2[nH]ccc2c1)c1cc(Cl)cc(Cl)c1>>O=C(NCc1ccccc1)n1ccc2cc(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)ccc21 -US20050085494A1,8,OCc1cnc2snnc2c1>>O=Cc1cnc2snnc2c1 -US20140112945A1,6,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](Cc4ccc(O)cc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)Cc4ccc(O)cc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US04640916,1,CN1C(=O)C(CCCl)Sc2ccccc21.Fc1ccc(N2CCNCC2)cc1>>CN1C(=O)C(CCN2CCN(c3ccc(F)cc3)CC2)Sc2ccccc21 -US08552196B2,2,Nc1cccc(-c2nnco2)c1.O=C(O)c1cc(Br)ccn1>>O=C(Nc1cccc(-c2nnco2)c1)c1cc(Br)ccn1 -US20090048303A1,9,NC(=O)c1cc2ccccc2[nH]1>>N#Cc1cc2ccccc2[nH]1 -US06498196B1,9,COc1ccc2c(c1)C(C)(C)C(=O)CC2.NO>>COc1ccc2c(c1)C(C)(C)C(=NO)CC2 -US06391902B1,2,CCO.O=C(O)c1cccc2c1Cc1c-2[nH]c2ccc(Cl)cc12>>CCOC(=O)c1cccc2c1Cc1c-2[nH]c2ccc(Cl)cc12 -US20050282858A1,3,CCCC[Sn](CCCC)(CCCC)c1ccncc1.O=C1O[C@]2(CCN(C(=O)C3(c4ccc(Br)cc4)CC3)C2)c2ccccc21>>O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccncc5)cc4)CC3)C2)c2ccccc21 -US08314103B2,2,N#Cc1ccc(N)cn1.O=C(OC(=O)C(F)(F)Cl)C(F)(F)Cl>>N#Cc1ccc(NC(=O)C(F)(F)Cl)cn1 -US07402608B2,6,COC(=O)c1sc(-c2ccc(Cl)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCN(C)CC1>>CC1CCC(C(=O)N(c2cc(-c3ccc(Cl)cc3)sc2C(=O)O)C2CCN(C)CC2)CC1 -US07049444B2,4,CCCCCCN1CC2C(C1)C2(C)c1ccc(N)c(N)c1.O=C(O)C(F)(F)F>>CCCCCCN1CC2C(C1)C2(C)c1ccc2[nH]c(C(F)(F)F)nc2c1 -US20100144787A1,1,CC(C)I.CC1(C)OB(c2cc[nH]n2)OC1(C)C>>CC(C)n1ccc(B2OC(C)(C)C(C)(C)O2)n1 -US08828401B2,2,CC(C)(C)OC(=O)[C@@H](N)Cc1ccccc1.CO[C@H]([C@@H](C)C(=O)O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21>>CO[C@H]([C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21 -US20140235672A1,7,COC(=O)C1C(=O)c2ccccc2OC1c1ccc(Cl)c(C(F)(F)F)c1>>COC(=O)C1C(O)c2ccccc2OC1c1ccc(Cl)c(C(F)(F)F)c1 -US20150111887A1,1,CC(C)(C)[S@](N)=O.O=C(c1ccc(F)cc1)C(F)(F)F>>CC(C)(C)[S@@](=O)/N=C(/c1ccc(F)cc1)C(F)(F)F -US20150023913A1,3,CCOC(=O)C(F)(F)Br.O=C1CCCCO1>>CCOC(=O)C(F)(F)C1(O)CCCCO1 -US20080108629A1,2,CCCCCN.COC(=O)c1cc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1C(=O)OCc1ccccc1>>CCCCCNC(=O)c1cc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1C(=O)OCc1ccccc1 -US20140296206A1,1,CN1CCN(CCCOS(C)(=O)=O)CC1.COc1cc2ncnc(N3CCN(c4ncc(Cc5ccccc5)cn4)CC3)c2cc1O>>COc1cc2ncnc(N3CCN(c4ncc(Cc5ccccc5)cn4)CC3)c2cc1OCCCN1CCN(C)CC1 -US20140112945A1,2,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1ccccc1.COc1ccc(C2=NN(C3CCNCC3)C(=O)C(C)(C)C2)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)C[C@@H](Cc4ccccc4)NC(=O)OC(C)(C)C)CC3)C(=O)C(C)(C)C2)cc1OC -US08354444B2,6,CC(C)(C)OC(=O)C1NC(CC(C)(C)c2ccccc2)C(C#N)(c2ccc(Cl)cc2F)C1c1cccc(Cl)c1F>>CC(C)(CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F)c1ccccc1 -US20090118284A1,2,Fc1cnc(-c2ccc(C3=CCNCC3)cc2F)nc1.O=C(Cl)CCl>>O=C(CCl)N1CC=C(c2ccc(-c3ncc(F)cn3)c(F)c2)CC1 -US04482561,1,CN1CCC(OC(=O)CCl)(c2ccccc2)CC1.O=C(O)c1ccccc1Nc1ccnc2c(C(F)(F)F)cccc12>>CN1CCC(OC(=O)COC(=O)c2ccccc2Nc2ccnc3c(C(F)(F)F)cccc23)(c2ccccc2)CC1 -US20060247251A1,1,N#Cc1ncc2cc(CBr)n(CCc3ccc(Cl)cc3)c2n1.Oc1ccc(F)cc1F>>N#Cc1ncc2cc(COc3ccc(F)cc3F)n(CCc3ccc(Cl)cc3)c2n1 -US20140213581A1,3,C=C[Sn](CCCC)(CCCC)CCCC.N#Cc1ncc(Cl)cc1Br>>C=Cc1cc(Cl)cnc1C#N -US06867298B2,1,Cc1cc(C)cc(I)c1.c1ccc(Nc2ccccc2)cc1>>Cc1cc(C)cc(N(c2ccccc2)c2ccccc2)c1 -US20090239848A1,2,O=C(O)CC(=O)Nc1ccc(-c2ccccc2)cc1.O=C(c1ccccc1Br)N1CCCNCC1>>O=C(CC(=O)N1CCCN(C(=O)c2ccccc2Br)CC1)Nc1ccc(-c2ccccc2)cc1 -US04849419,1,O=C(Sc1c(F)c(F)c(F)c(F)c1F)c1cccc(O)c1.S=C(Cl)Cl>>O=C(Sc1c(F)c(F)c(F)c(F)c1F)c1cccc(OC(=S)Cl)c1 -US07601843B2,1,COC(=O)C12CC3CC(CC(CO)(C3)C1)C2.Cc1ccc(NC2CCNCC2)nc1>>COC(=O)C12CC3CC(CC(CN4CCC(Nc5ccc(C)cn5)CC4)(C3)C1)C2 -US09073864B2,2,CCOC(=O)[C@@H]1CCCNC1.CCc1cnc(-c2ccc(C(CCC(F)(F)F)Nc3ccc(C(=O)O)cc3)c(C)c2)nc1>>CCOC(=O)[C@@H]1CCCN(C(=O)c2ccc(NC(CCC(F)(F)F)c3ccc(-c4ncc(CC)cn4)cc3C)cc2)C1 -US07935721B2,3,O=C1N(Cc2ccccn2)c2cccc(Br)c2C12COc1cc3c(cc12)CCO3.OB(O)c1cccnc1>>O=C1N(Cc2ccccn2)c2cccc(-c3cccnc3)c2C12COc1cc3c(cc12)CCO3 -US20150218170A1,1,CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12.CS(=O)(=O)c1ccc(N)cc1>>CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Nc3ccc(S(C)(=O)=O)cc3)nc12 -US08445480B2,9,CC(C)C1(C(N)=O)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)C1(C#N)CCN(C(=O)OC(C)(C)C)CC1 -US05239080,1,COc1ccccc1O.Clc1ccc(-c2coc(CCCI)n2)cc1>>COc1ccccc1OCCCc1nc(-c2ccc(Cl)cc2)co1 -US20110071194A1,5,C[C@H](N)[C@@H](COc1ccc(F)cc1F)Oc1ccc2c(cnn2-c2ccc(F)cc2)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C[C@H](NC(=O)C(F)(F)F)[C@@H](COc1ccc(F)cc1F)Oc1ccc2c(cnn2-c2ccc(F)cc2)c1 -US20110124624A1,2,CC(C)(C)N.CC(C)(C)OC(=O)NCCC(=O)O>>CC(C)(C)NC(=O)CCNC(=O)OC(C)(C)C -US20090137549A1,3,O=c1[nH]c(C2CN(c3nc(Br)cs3)C2)nc2c1cnn2C1CCCCC1.OB(O)c1ccccc1>>O=c1[nH]c(C2CN(c3nc(-c4ccccc4)cs3)C2)nc2c1cnn2C1CCCCC1 -US20120283273A1,7,CC(=O)c1cc(Cl)ncn1>>CC(O)c1cc(Cl)ncn1 -US20140113922A1,7,O=[N+]([O-])CCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>NCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1 -US20090286778A1,2,CC(C)N=C=O.O=C(CC1CCNCC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2>>CC(C)NC(=O)N1CCC(CC(=O)Nc2ccc3cc2CCc2cncc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US20100120841A1,1,CC(C)(C)O[Si](C)(C)OC1Cc2ccc(O)c3cccc1c23.CI>>COc1ccc2c3c(cccc13)C(O[Si](C)(C)OC(C)(C)C)C2 -US07368578B2,1,CCOC(=O)Cc1ccc(-c2nc(COc3ccc(CCl)cc3OC)c(C)o2)cc1.O=C(OCc1nc(/C=C/c2cn(-c3ccccc3)nc2O)cs1)c1ccccc1>>CCOC(=O)Cc1ccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4/C=C/c4csc(COC(=O)c5ccccc5)n4)cc3OC)c(C)o2)cc1 -US06207668B1,1,COCc1ncnc(Cl)c1OC.NC1CSC(c2ccccc2)C1>>COCc1ncnc(NC2CSC(c3ccccc3)C2)c1OC -US09085575B2,1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCN(c2ccc(C=O)c(F)c2)CC1 -US20070161574A1,2,CN.COC(=O)C(NC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C1CCCCC1>>CNC(=O)C(NC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C1CCCCC1 -US04420487,4,Nc1cc(Cl)c(S(N)(=O)=O)cc1N.O=C(O)C(F)F>>NS(=O)(=O)c1cc2[nH]c(C(F)F)nc2cc1Cl -US20100016319A1,1,CC(=O)N1CCNCC1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)cc1>>CC(=O)N1CCN(c2nccc(Oc3ccccc3CNC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)n2)CC1 -US20100173944A1,1,CCCCCCCCOc1ccnc(CCl)c1C.Sc1nc2ccccc2[nH]1>>CCCCCCCCOc1ccnc(CSc2nc3ccccc3[nH]2)c1C -US20140378475A1,1,CI.Cc1c(Br)cccc1-n1c(=O)[nH]c2c(F)cccc2c1=O>>Cc1c(Br)cccc1-n1c(=O)c2cccc(F)c2n(C)c1=O -US06734200B1,2,CC(=O)OC(C)=O.N[C@H]1CCN(c2ccc(N3C[C@H](CN(C(=O)OCC(Cl)(Cl)Cl)c4ccon4)OC3=O)cc2F)C1>>CC(=O)N[C@H]1CCN(c2ccc(N3C[C@H](CN(C(=O)OCC(Cl)(Cl)Cl)c4ccon4)OC3=O)cc2F)C1 -US08399505B2,6,O=C(/C=C/c1ccn(S(=O)(=O)Cc2ccccc2)c1)NOC1CCCCO1>>O=C(C=Cc1ccn(S(=O)(=O)Cc2ccccc2)c1)NO -US20110183975A1,1,CC(C)I.c1cc2cc[nH]c2cn1>>CC(C)n1ccc2ccncc21 -US05902803,7,N#Cc1cccc2c1Cc1c-2[nH]c(=O)c2nccn12>>NCc1cccc2c1Cc1c-2[nH]c(=O)c2nccn12 -US08283340B2,7,CCOC(=O)c1ccc(OCc2cc3ccccc3o2)cc1>>OCc1ccc(OCc2cc3ccccc3o2)cc1 -US08598154B2,1,C1CNC1.COC[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(Cl)nc1)C2>>COC[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCC3)nc1)C2 -US20030171359A1,1,CC(=O)NCCN.Cc1cnc(Cl)nc1Cl>>CC(=O)NCCNc1nc(Cl)ncc1C -US20100240658A1,7,COC(=O)c1ccc(-c2noc(-c3ccc(N4CCCCC4C)c([N+](=O)[O-])c3)n2)cc1F>>COC(=O)c1ccc(-c2noc(-c3ccc(N4CCCCC4C)c(N)c3)n2)cc1F -US08637500B2,3,COc1cc(B(O)O)ccn1.Cc1ccc(Nc2ccc(Oc3ncccc3Br)cc2)nc1>>COc1cc(-c2cccnc2Oc2ccc(Nc3ccc(C)cn3)cc2)ccn1 -US20130303507A1,7,CCOC(=O)C(C)(C)N[C@@H]1CC[C@@H](N)CC1>>CC(C)(CO)N[C@@H]1CC[C@@H](N)CC1 -US20090069302A1,2,COc1ccc(S(=O)(=O)Cl)cc1F.COc1ccc(S(=O)(=O)N2C[C@H](C)NC[C@@H]2C)cc1OC>>COc1ccc(S(=O)(=O)N2C[C@H](C)N(S(=O)(=O)c3ccc(OC)c(OC)c3)C[C@@H]2C)cc1F -US08586604B2,2,CC(C)(F)C(=O)O.NCc1ccc(Cl)c(Nc2nc3cc(C(=O)N[C@@H]4CC[C@@H](C(F)(F)F)CC4)c(OCC(F)F)nc3[nH]2)c1Cl>>CC(C)(F)C(=O)NCc1ccc(Cl)c(Nc2nc3cc(C(=O)N[C@@H]4CC[C@@H](C(F)(F)F)CC4)c(OCC(F)F)nc3[nH]2)c1Cl -US20100130489A1,3,OB(O)c1ccccc1C(F)(F)F.OCCCNc1nc2cc(Br)ccc2n2ccnc12>>OCCCNc1nc2cc(-c3ccccc3C(F)(F)F)ccc2n2ccnc12 -US08080571B2,1,CC(C)Cc1cc(-c2cccc(CBr)c2)c(S(=O)(=O)NC(C)(C)C)s1.c1c[nH]cn1>>CC(C)Cc1cc(-c2cccc(Cn3ccnc3)c2)c(S(=O)(=O)NC(C)(C)C)s1 -US20070225292A1,1,CCCI.O=C(NCC1CCCCC1)c1nc(O)ccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12>>CCCOc1ccc(NC(=O)c2ccc(Cn3ccnn3)c3ccccc23)c(C(=O)NCC2CCCCC2)n1 -US20090012129A1,1,CCOCCBr.COC(=O)c1ccc(I)c(O)c1>>CCOCCOc1cc(C(=O)OC)ccc1I -US20120226035A1,1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCNCC1.COc1ncc2ccc(=O)n(CC=O)c2n1>>COc1ncc2ccc(=O)n(CCN3CCC(N(Cc4cc5c(cn4)OCCO5)C(=O)OC(C)(C)C)CC3)c2n1 -US09096592B2,6,CCOC(=O)c1cnc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N>>Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)ncc1C(=O)O -US20060122065A1,7,C#CCOc1ccc(CCC(=O)NCc2ccc(C=O)cc2)cc1OC>>C#CCOc1ccc(CCC(=O)NCc2ccc(CO)cc2)cc1OC -US20150183801A1,3,CC1(C)OB(c2cncc(C#N)c2)OC1(C)C.O=C(Nc1ccc(C(F)(F)C(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1>>N#Cc1cncc(-c2cc(C(=O)Nc3ccc(C(F)(F)C(F)(F)F)cc3)cnc2N2CC[C@@H](O)C2)c1 -US20130150584A1,2,COC(=O)c1cc(F)c2cncn2c1Nc1ccc(Br)cc1F.C[C@H](O)CON>>C[C@H](O)CONC(=O)c1cc(F)c2cncn2c1Nc1ccc(Br)cc1F -US20150274703A1,1,CC(C)(C)OC(=O)c1c[nH]c2ccc(Cl)cc12.O=C(CBr)OCc1ccccc1>>CC(C)(C)OC(=O)c1cn(CC(=O)OCc2ccccc2)c2ccc(Cl)cc12 -US07041687B2,6,COC(=O)C(CC(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1>>COC(=O)C(CC(=O)O)c1ccc(Cl)c(Cl)c1 -US06797726B1,6,COC(=O)Cc1cc2ccsc2c(OC)c1F>>COc1c(F)c(CC(=O)O)cc2ccsc12 -US20150232459A1,1,COC(=O)NCCCc1cc([C@@H](C)N(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H](COS(C)(=O)=O)O2)C2CC2)cc(OC)n1.O=C1NC(=O)c2ccccc21>>COC(=O)NCCCc1cc([C@@H](C)N(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H](CN3C(=O)c4ccccc4C3=O)O2)C2CC2)cc(OC)n1 -US20090012055A1,1,COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(CCl)cc3)cc21.c1c[nH]cn1>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(Cn4ccnc4)cc3)cc21 -US20080004268A1,2,COc1cccc(-c2c(C(=O)O)[nH]c3ccc(NS(=O)(=O)c4ccc(C(C)(C)C)cc4)cc23)c1.NCCO>>COc1cccc(-c2c(C(=O)NCCO)[nH]c3ccc(NS(=O)(=O)c4ccc(C(C)(C)C)cc4)cc23)c1 -US04091023,1,Brc1ccc2c(c1)CC(N1CCNCC1)c1ccccc1O2.O=C1OCCN1CCCl>>O=C1OCCN1CCN1CCN(C2Cc3cc(Br)ccc3Oc3ccccc32)CC1 -US20060094716A1,1,Cc1cc(NC(=O)NC2CCNC2)c2ccccc2n1.O=Cc1cccc(B(O)O)c1>>Cc1cc(NC(=O)NC2CCN(Cc3cccc(B(O)O)c3)C2)c2ccccc2n1 -US06790860B2,1,CC(C)(C)OC(=O)CBr.COc1ccc(CS[C@@H]2C[C@@H](CNCc3cc(F)ccc3F)N(C(=O)OC(C)(C)C)C2)cc1>>COc1ccc(CS[C@@H]2C[C@@H](CN(CC(=O)OC(C)(C)C)Cc3cc(F)ccc3F)N(C(=O)OC(C)(C)C)C2)cc1 -US06407261B1,1,Clc1cccc(CBr)c1.O=C1CCCc2[nH]ccc21>>O=C1CCCc2c1ccn2Cc1cccc(Cl)c1 -US20120190635A1,6,CC(=O)OC1C(OC2CCCCCCCCCCCCC2)OC(C)CC1N(C)C>>CC1CC(N(C)C)C(O)C(OC2CCCCCCCCCCCCC2)O1 -US08486962B2,7,O=C1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>Nc1ccc(N2CCC(=O)CC2)cc1 -US08846709B2,1,COc1cc2c(Cl)c([N+](=O)[O-])cnc2cc1-c1c(C)noc1C.NCC1CCOCC1>>COc1cc2c(NCC3CCOCC3)c([N+](=O)[O-])cnc2cc1-c1c(C)noc1C -US08461330B2,1,CNCCNC.Fc1ccccn1>>CNCCN(C)c1ccccn1 -US08399676B2,1,CI.Cc1ccc(S(=O)(=O)N2CCC(N)(C(=O)Nc3ccc(OC(F)(F)F)cc3)CC2)cc1>>CNC1(C(=O)Nc2ccc(OC(F)(F)F)cc2)CCN(S(=O)(=O)c2ccc(C)cc2)CC1 -US20090131455A1,1,Cc1sc2nc(CCl)[nH]c(=O)c2c1-c1ccccc1.O=Cc1c[nH]nc1C(F)(F)F>>Cc1sc2nc(Cn3cc(C=O)c(C(F)(F)F)n3)[nH]c(=O)c2c1-c1ccccc1 -US04151288,2,CN(C)CCN=C=S.NCCNCc1ncccn1>>CN(C)CCNC(=S)NCCNCc1ncccn1 -US20080132477A1,8,CC(C)(C)c1ccnc(CO)c1>>CC(C)(C)c1ccnc(C=O)c1 -US20110065702A1,3,Nc1ccc2c(c1)CC(=O)N2.O=Cc1ccc2[nH]nnc2c1>>Nc1ccc2c(c1)/C(=C\c1ccc3[nH]nnc3c1)C(=O)N2 -US04356182,6,O=C(O)[C@@H]1CC(O)(Cc2ccncc2)CN1C(=O)OCc1ccccc1>>O=C(O)[C@@H]1CC(O)(Cc2ccncc2)CN1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4cn(CCC)cn4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cn(CCC)cn4)cc2)CCN3CC(C)C)cc1 -US20070167486A1,6,COC(=O)CC1=CCCN(Cc2ccc(OC)cc2OC)C1=O>>COc1ccc(CN2CCC=C(CC(=O)O)C2=O)c(OC)c1 -US08003662B2,1,C#CC(C)(C)Cl.CCNCC>>C#CC(C)(C)N(CC)CC -US20040006141A1,6,CCCCC(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccc3OC)cc2)cc1)C(=O)OCC>>CCCCC(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccc3OC)cc2)cc1)C(=O)O -US04663319,7,CCOC(=O)CC(=O)N(CCC(=O)OC)Cc1ccc([N+](=O)[O-])cc1>>CCOC(=O)CC(=O)N(CCC(=O)OC)Cc1ccc(N)cc1 -US05039805,2,CC(C)(C)OC(=O)Nc1cccc(C(=O)O)c1.NCCC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)Nc1cccc(C(=O)NCCC(=O)OCc2ccccc2)c1 -US04405357,1,CC1(C)CONC1=O.Fc1ccc(CBr)c(Cl)c1>>CC1(C)CON(Cc2ccc(F)cc2Cl)C1=O -US20100331326A1,1,Brc1ccccc1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccccc2)C1=O -US20080306046A1,6,COC(=O)/C=C/c1cncc(OC(=O)N2CCC(Oc3ccc(OCc4cccc(F)c4)cc3)CC2)c1>>O=C(O)/C=C/c1cncc(OC(=O)N2CCC(Oc3ccc(OCc4cccc(F)c4)cc3)CC2)c1 -US04131737,1,CCOC(=O)CS.OC(CCCCl)c1ccco1>>CCOC(=O)CSCCCC(O)c1ccco1 -US20080318923A1,1,CN(C)C(=O)[C@@H]1C[C@@H](O)CN1.COc1ccc(CO[Si](C)(C)C(C)(C)C)cc1C1(O)C(=O)Nc2ccc(Cl)cc21>>COc1ccc(CO[Si](C)(C)C(C)(C)C)cc1C1(N2C[C@H](O)C[C@H]2C(=O)N(C)C)C(=O)Nc2ccc(Cl)cc21 -US20070197571A1,1,C=CC(C)O.O=Cc1cccc(O)c1>>C=CC(C)Oc1cccc(C=O)c1 -US06420375B1,7,COC(=O)/C(C)=C/c1ccc2ccccc2c1>>C/C(=C\c1ccc2ccccc2c1)CO -US20110077235A1,2,Nc1cc(N2CCOCC2)n2nccc2n1.O=C(Cl)c1ccc(Br)cc1>>O=C(Nc1cc(N2CCOCC2)n2nccc2n1)c1ccc(Br)cc1 -US04091115,7,CN(C)C1C=Cc2ccccc2CC1>>CN(C)C1CCc2ccccc2CC1 -US06069156,1,CCCc1cc2ccc(C(=O)OC)cc2[nH]1.Clc1ccccc1CBr>>CCCc1cc2ccc(C(=O)OC)cc2n1Cc1ccccc1Cl -US08575154B2,1,COc1cccc(I)c1.Nc1ncccc1-c1ccc(O)cc1>>COc1cccc(Oc2ccc(-c3cccnc3N)cc2)c1 -US20140371199A1,3,COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cn1.N#Cc1ccc(-c2cnc3cnc(Br)cn23)cc1>>COC(=O)c1ccc(-c2cn3c(-c4ccc(C#N)cc4)cnc3cn2)cn1 -US20090227570A1,2,CC(C)N=C=O.COc1c(Cl)cc(Cl)c2c1C(Nc1ccc3cc(N)ccc3n1)CC2>>COc1c(Cl)cc(Cl)c2c1C(Nc1ccc3cc(NC(=O)NC(C)C)ccc3n1)CC2 -US20060217362A1,2,CN.O=S(=O)(Cl)c1c(Cl)cccc1Cl>>CNS(=O)(=O)c1c(Cl)cccc1Cl -US06265572B1,6,CC(C)(C)OC(=O)N[C@H]1CSSC[C@@H](C(=O)OC(C)(C)C)NC(=O)C2(CCCC2)CCNC1=O>>CC(C)(C)OC(=O)[C@@H]1CSSC[C@H](N)C(=O)NCCC2(CCCC2)C(=O)N1 -US20090036474A1,1,C=C(C)CN.COc1ccc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)cc1C=O>>C=C(C)CNCc1cc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)ccc1OC -US07652058B2,2,C1CCNCC1.O=C(O)Cc1ccc(F)cc1>>O=C(Cc1ccc(F)cc1)N1CCCCC1 -US06969711B2,8,CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ccccc3[nH]2)CC1.O=C(OO)c1cccc(Cl)c1>>CSc1cc(C)nc(S(C)=O)c1NC(=O)CN1CCN(CCSc2nc3ccccc3[nH]2)CC1 -US08338598B2,7,CC(C)C(=O)Oc1c(-c2c(C(F)(F)F)nn(C)c2OC(F)F)c(=O)n(CC(F)F)c2nccnc12>>Cn1nc(C(F)(F)F)c(-c2c(O)c3nccnc3n(CC(F)F)c2=O)c1OC(F)F -US08410104B2,1,CCCCc1noc(C)c1CO.Clc1ccc(Cl)nn1>>CCCCc1noc(C)c1COc1ccc(Cl)nn1 -US20120015991A1,3,CC1(C)OB(c2ccc(C3(C(=O)NS(C)(=O)=O)CC3)cc2)OC1(C)C.COc1cc(Br)ccc1-c1onc(C)c1NC(=O)O[C@H](C)c1cccc(C(F)(F)F)c1>>COc1cc(-c2ccc(C3(C(=O)NS(C)(=O)=O)CC3)cc2)ccc1-c1onc(C)c1NC(=O)O[C@H](C)c1cccc(C(F)(F)F)c1 -US20130178460A1,2,Nc1cnn2cccnc12.O=C(O)c1csc2cnc(Cl)nc12>>O=C(Nc1cnn2cccnc12)c1csc2cnc(Cl)nc12 -US08318949B2,6,C=CCCN1CCN(c2nc(C)c(C(=O)OCC)s2)C1=O>>C=CCCN1CCN(c2nc(C)c(C(=O)O)s2)C1=O -US04889857,1,CCOC(=O)CC(=O)c1cc(F)c(F)c(F)c1F.CN(C)CC1CNCCO1>>CCOC(=O)CC(=O)c1cc(F)c(N2CCOC(CN(C)C)C2)c(F)c1F -US20100311748A1,2,Cc1ccc(-c2ncc[nH]2)cc1N.O=C(Cl)c1ccc(Oc2ccccc2)nc1>>Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(Oc2ccccc2)nc1 -US04906634,7,CCCCN1CCCC1COc1ccc([N+](=O)[O-])cc1>>CCCCN1CCCC1COc1ccc(N)cc1 -US20080009518A1,6,C[C@@H](O[C@H]1CCc2c(ccc(CNC(=O)OC(C)(C)C)[n+]2[O-])[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CCc2c(ccc(CN)[n+]2[O-])[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20040073025A1,1,NC1CC1.O=C(CBr)NCc1cc(Cl)ccc1-n1cnnn1>>O=C(CNC1CC1)NCc1cc(Cl)ccc1-n1cnnn1 -US20070099944A1,2,COC(=O)C1=CNC(=O)NC1c1ccc(F)cc1.Nc1ccc2[nH]ncc2c1>>O=C1NC=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)cc2)N1 -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)cc1)Nc1ccccc1>>O=C(NCCOc1ccc(CC(Nc2ccccc2)C(=O)O)cc1)c1ccc(-c2ccccn2)cc1 -US20110136787A1,9,COc1ccccc1C1CCC(=O)C=C1c1ccccc1.NO>>COc1ccccc1C1CCC(=NO)C=C1c1ccccc1 -US20130102568A1,4,CC(C)ON=C(C#N)C(=NOC(C)C)n1cncn1.C[Si](C)(C)N=[N+]=[N-]>>CC(C)ON=C(C(=NOC(C)C)n1cncn1)c1nnn[nH]1 -US20080033049A1,3,COc1ccc(B(O)O)cc1.O=Cc1ccc(OS(=O)(=O)C(F)(F)F)c(Cl)c1>>COc1ccc(-c2ccc(C=O)cc2Cl)cc1 -US08481539B2,2,Cc1ccc(N)cc1C#Cc1cncc2c1cnn2C.O=C=Nc1ccccc1>>Cc1ccc(NC(=O)Nc2ccccc2)cc1C#Cc1cncc2c1cnn2C -US20080306111A1,6,CC(=O)Nc1ccccc1-c1ccc2c(c1)Oc1ccccc1C2C1CCN(C(=O)C(F)(F)F)CC1>>CC(=O)Nc1ccccc1-c1ccc2c(c1)Oc1ccccc1C2C1CCNCC1 -US05631264,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1>>C=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 -US05409886,2,CC(=O)C(C)NC(C)(C)c1cccc(Cl)c1.O=C(Cl)Cc1ccccc1F>>CC(=O)C(C)N(C(=O)Cc1ccccc1F)C(C)(C)c1cccc(Cl)c1 -US05034381,1,NCCC1=CCCCC1.Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>Nc1nc(NCCC2=CCCCC2)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O -US20140163012A1,6,CC(C)(C)OC(=O)N1CCc2oc3cc(-n4ccc(-c5ccc(C(F)(F)F)cc5)cc4=O)ccc3c2C1>>O=c1cc(-c2ccc(C(F)(F)F)cc2)ccn1-c1ccc2c3c(oc2c1)CCNC3 -US20100137313A1,1,CN(C)CCCN.Clc1ncc(Br)c(Cl)n1>>CN(C)CCCNc1nc(Cl)ncc1Br -US20070225232A1,6,COC(C)(OC)c1ncc(C2(O)CCCn3cncc32)s1>>CC(=O)c1ncc(C2(O)CCCn3cncc32)s1 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2C(F)(F)F)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2C(F)(F)F)CN1 -US05292767,2,CC(C)(S)[C@H]1C[C@H](C(=O)O)CS1.CCO>>CCOC(=O)[C@@H]1CS[C@@H](C(C)(C)S)C1 -US04600429,1,NCCCCN.O=P(O)(O)CCl>>NCCCCNCP(=O)(O)O -US20130178459A1,3,COc1ccc2[nH]c(=O)c3sccc3c2c1Br.Cc1cc(Br)ccc1NS(C)(=O)=O>>COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(NS(C)(=O)=O)c(C)c1 -US07893099B2,2,N#CCN.O=C(O)[C@@H]1CC(S(=O)(=O)c2ccc(F)cc2Cl)C[C@H]1COc1ccc(F)cc1>>N#CCNC(=O)[C@@H]1CC(S(=O)(=O)c2ccc(F)cc2Cl)C[C@H]1COc1ccc(F)cc1 -US09067937B2,3,CC(=O)c1cnc2ccc(Cl)nc2c1NC1CCC(CN2CC[C@@H](F)C2)CC1.CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C>>CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1NC1CCC(CN2CC[C@@H](F)C2)CC1 -US20040209916A1,1,CI.Cc1ccc(O)c([C@H](CCN(C(C)C)C(C)C)c2ccccc2)c1>>Cc1ccc(O)c([C@H](CC[N+](C)(C(C)C)C(C)C)c2ccccc2)c1 -US20130158075A1,2,CC(=O)NN.O=C(O)CC1CCC(c2ncc(-c3ccc([N+](=O)[O-])cc3)s2)CC1>>CC(=O)NNC(=O)CC1CCC(c2ncc(-c3ccc([N+](=O)[O-])cc3)s2)CC1 -US05750545,2,CC(=O)OC(C)=O.CNC(=S)n1nc(N)nc1N>>CNC(=S)n1nc(NC(C)=O)nc1N -US04894367,7,CCCCCCCCCCCCCCc1ccc(C(C)=O)c(O)c1>>CCCCCCCCCCCCCCc1ccc(CC)c(O)c1 -US04617394,1,C[O-].Nc1cccc2ccc(Cl)nc12>>COc1ccc2cccc(N)c2n1 -US20080248537A1,2,CC(C)(C)C(=O)Cl.Nc1cnc(Br)cn1>>CC(C)(C)C(=O)Nc1cnc(Br)cn1 -US04563455,1,ClCc1nc2ccccc2[nH]1.c1c[nH]cn1>>c1ccc2[nH]c(Cn3ccnc3)nc2c1 -US20100056513A1,3,Fc1cc2c(cc1Br)OC(c1ccccc1F)(c1ccc(Cl)cc1Cl)O2.O=C(Cl)N1CCOCC1>>O=C(c1cc2c(cc1F)OC(c1ccccc1F)(c1ccc(Cl)cc1Cl)O2)N1CCOCC1 -US20120009151A1,1,CCCc1nc(Cl)nc(Nc2cccc(C(C)C)c2)n1.CS(=O)(=O)N1CCC(N)CC1>>CCCc1nc(Nc2cccc(C(C)C)c2)nc(NC2CCN(S(C)(=O)=O)CC2)n1 -US20090253687A1,1,CCOC(=O)CBr.O=[N+]([O-])c1cc(Br)ccc1O>>CCOC(=O)COc1ccc(Br)cc1[N+](=O)[O-] -US20040180947A1,7,COC(=O)c1ccc2nc(C)n(Cc3ccc([N+](=O)[O-])cc3Cl)c2n1>>COC(=O)c1ccc2nc(C)n(Cc3ccc(N)cc3Cl)c2n1 -US08299080B2,7,CCOC(=O)CCc1nccn1-c1ccc(F)cc1[N+](=O)[O-]>>CCOC(=O)CCc1nccn1-c1ccc(F)cc1N -US20100278833A1,1,COC(=O)c1sc(-n2cnc3ccncc32)cc1O.FC(F)(F)c1cccc(CBr)c1>>COC(=O)c1sc(-n2cnc3ccncc32)cc1OCc1cccc(C(F)(F)F)c1 -US20120196884A1,2,Cn1nc(C(F)(F)F)cc1-c1ccc(S(=O)(=O)Cl)s1.Nc1ccc(NC(=O)Nc2ccccc2)c(Cl)c1>>Cn1nc(C(F)(F)F)cc1-c1ccc(S(=O)(=O)Nc2ccc(NC(=O)Nc3ccccc3)c(Cl)c2)s1 -US20080027050A1,6,COC(=O)c1ccc(OCCn2ncc3nc(C(=O)NCc4ccc(F)c(OC)c4)[nH]c(=O)c32)cc1>>COc1cc(CNC(=O)c2nc3cnn(CCOc4ccc(C(=O)O)cc4)c3c(=O)[nH]2)ccc1F -US06265423B1,3,CC1(C)CCC(C)(C)c2ccccc21.O=C(Cl)Cc1ccc(Br)cc1>>CC1(C)CCC(C)(C)c2cc(C(=O)Cc3ccc(Br)cc3)ccc21 -US20100022560A1,3,CCC(CC)c1cc(C)nc2c(I)c(C)nn12.Cc1ccsc1[Zn+]>>CCC(CC)c1cc(C)nc2c(-c3sccc3C)c(C)nn12 -US20020099212A1,2,CO.Cc1cc2cc(C(=O)O)ccc2s1>>COC(=O)c1ccc2sc(C)cc2c1 -US20050054633A1,2,CN1C(=O)[C@@H](N)c2ccccc2-c2ccccc21.O=C(O)CC(=O)NCCC(F)(F)C(F)(F)F>>CN1C(=O)[C@@H](NC(=O)CC(=O)NCCC(F)(F)C(F)(F)F)c2ccccc2-c2ccccc21 -US04968682,2,CC(C)Nc1ccccc1[N+](=O)[O-].CCOC(=O)C(=O)Cl>>CCOC(=O)C(=O)N(c1ccccc1[N+](=O)[O-])C(C)C -US05030654,2,N[C@@H](COCc1ccccc1)C(=O)O.O=C(OCc1ccccc1)OC(=O)OCc1ccccc1>>O=C(N[C@@H](COCc1ccccc1)C(=O)O)OCc1ccccc1 -US20040110746A1,1,CCCCN1CCN(C(=O)c2ccc(C=O)cc2)CC1.Nc1ccc(C(F)(F)F)cc1>>CCCCN1CCN(C(=O)c2ccc(CNc3ccc(C(F)(F)F)cc3)cc2)CC1 -US20140288071A1,3,COC(=O)CSc1ncnc2sc(C)c(Br)c12.OB(O)C1CC1>>COC(=O)CSc1ncnc2sc(C)c(C3CC3)c12 -US20090203689A1,1,Fc1ccccc1S.O[C@@H]1CCC[C@H]1Nc1ncnc2c1ncn2C1O[C@H](CCl)[C@@H](O)[C@H]1O>>O[C@@H]1CCC[C@H]1Nc1ncnc2c1ncn2C1O[C@H](CSc2ccccc2F)[C@@H](O)[C@H]1O -US07465744B2,3,CC(=O)NCCc1ccccc1.O=C(Cl)c1ccccc1>>CC(=O)NCCc1ccc(C(=O)c2ccccc2)cc1 -US20040122244A1,2,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.Nc1cccnc1Cl>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3cccnc3Cl)c2)=C(C)C1=O -US05328922,2,CNc1ccc2c(ccn2C)c1.O=C=Nc1cccnc1>>CN(C(=O)Nc1cccnc1)c1ccc2c(ccn2C)c1 -US20150284411A1,3,CC(=O)c1ccc(B(O)O)cc1.O[C@@H]1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(Br)cc5)c(Cl)cc4[nH]3)CO[C@H]12>>CC(=O)c1ccc(-c2ccc(-c3nc4nc(O[C@@H]5CO[C@@H]6[C@H](O)CO[C@H]56)[nH]c4cc3Cl)cc2)cc1 -US20040138286A1,2,O=C(O)CO.c1cc2[nH]ncc2cc1NC1CC2CCC(C1)N2>>O=C(CO)N1C2CCC1CC(Nc1ccc3[nH]ncc3c1)C2 -US20150225396A1,6,CC(C)(C)OC(=O)CCc1nc2ncccc2c(=O)[nH]1>>O=C(O)CCc1nc2ncccc2c(=O)[nH]1 -US08426438B2,2,CS(=O)(=O)Cl.Cn1ncc2cc(CO)ccc21>>Cn1ncc2cc(COS(C)(=O)=O)ccc21 -US04510313,9,N=C(N)Nc1nc(C(=O)CBr)cs1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(=O)c1csc(NC(=N)N)n1 -US04839358,6,CC(=O)SCC(Cc1ccccc1)C(=O)NN1CCCCCC1>>O=C(NN1CCCCCC1)C(CS)Cc1ccccc1 -US06329381B1,1,Nc1nc(S)nc2c1nc(O)n2Cc1ccccc1.OCCOCCCl>>Nc1nc(SCCOCCO)nc2c1nc(O)n2Cc1ccccc1 -US20050096353A1,1,CCOC(=O)Cn1ccc2c(O)cccc21.Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1CCO>>CCOC(=O)Cn1ccc2c(OCCc3ccc(-c4ccc(C(F)(F)F)cc4)nc3C)cccc21 -US07560463B2,1,BrCCc1ccccc1.NC(=O)c1ccc(Oc2ccc3c(c2)CCNCC3)nc1>>NC(=O)c1ccc(Oc2ccc3c(c2)CCN(CCc2ccccc2)CC3)nc1 -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(N2CC(C)CC(C)C2)nc1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc(N2CC(C)CC(C)C2)nc1-c1ccc(C)cc1 -US20100121048A1,1,Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2Cc2ccc(O)cc2)c(-c2ccccc2)n1-c1ccccc1.N#CCCl>>Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2Cc2ccc(OCC#N)cc2)c(-c2ccccc2)n1-c1ccccc1 -US06767906B2,7,CCn1cnc2c(Nc3cccc([N+](=O)[O-])c3)nc(N[C@@H]3CC[C@@H](O)CC3)nc21>>CCn1cnc2c(Nc3cccc(N)c3)nc(N[C@@H]3CC[C@@H](O)CC3)nc21 -US20020156311A1,1,Cc1c(N(Cc2ccccc2)Cc2ccc(Oc3cccc(O)c3)cc2)cccc1[N+](=O)[O-].O=C1c2ccccc2C(=O)N1CCCO>>Cc1c(N(Cc2ccccc2)Cc2ccc(Oc3cccc(OCCCN4C(=O)c5ccccc5C4=O)c3)cc2)cccc1[N+](=O)[O-] -US05631401,7,O=Cc1ccc(Oc2ccccc2)cc1>>OCc1ccc(Oc2ccccc2)cc1 -US07183297B2,1,C1CCNC1.Cc1ccc(NC(=O)c2ccnc(Cl)c2)cc1-c1ccc(C(=O)O)cc1>>Cc1ccc(NC(=O)c2ccnc(N3CCCC3)c2)cc1-c1ccc(C(=O)O)cc1 -US04518415,6,C=C(CCC1OCCCO1)c1ccc(Cl)cc1Cl>>C=C(CCC=O)c1ccc(Cl)cc1Cl -US20140155384A1,1,Brc1ccc2ncccc2c1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2-c2ccc3ncccc3c2)CCN(C)C1 -US20050192303A1,1,COc1ccc(-c2nn3c(Cl)cc(Cl)cc3c2-c2ccnc(NC3CCCC3)n2)cc1.NC1CCCC1>>COc1ccc(-c2nn3c(NC4CCCC4)cc(Cl)cc3c2-c2ccnc(NC3CCCC3)n2)cc1 -US20090258917A1,2,Cc1ccc2oc(-c3cc(N)ccc3Cl)nc2c1.O=C(Cl)c1cccnc1Cl>>Cc1ccc2oc(-c3cc(NC(=O)c4cccnc4Cl)ccc3Cl)nc2c1 -US20100130558A1,6,CC(C)(C)OC(=O)N[C@H]1CC[C@@H]2CN(c3ccc(C(F)(F)F)cn3)C[C@H]12>>N[C@H]1CC[C@@H]2CN(c3ccc(C(F)(F)F)cn3)C[C@H]12 -US20100125064A1,2,CNC.Cc1ccc(S(=O)(=O)n2c(S(=O)(=O)Cl)cc3ccc(Cl)cc32)cc1>>Cc1ccc(S(=O)(=O)n2c(S(=O)(=O)N(C)C)cc3ccc(Cl)cc32)cc1 -US20130274260A1,3,Cc1ccc(B(O)O)cc1.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CCl)cc1>>Cc1ccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)cc1 -US04973474,1,CCO.Nc1cc(Cl)nc(N)[n+]1[O-]>>CCOc1cc(N)[n+]([O-])c(N)n1 -US20080004309A1,3,CCOC(=O)c1nc(Br)c2nc(-c3ccc(F)cc3)sc2c1O.C[Sn](C)(C)C>>CCOC(=O)c1nc(C)c2nc(-c3ccc(F)cc3)sc2c1O -US04361563,7,CC(=O)N(CCC(C)C)c1ccc(C2=NNC(=O)CC2C)cc1[N+](=O)[O-]>>CC(=O)N(CCC(C)C)c1ccc(C2=NNC(=O)CC2C)cc1N -US20110071194A1,2,CC(C)(C)C(=O)Cl.CCC[C@H](N)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1>>CCC[C@H](NC(=O)C(C)(C)C)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1 -US20090004185A1,1,Clc1nc(Cl)c2ccccc2n1.NCc1ccc(NC(=O)c2ccc(Cl)nc2)cc1>>O=C(Nc1ccc(CNc2nc(Cl)nc3ccccc23)cc1)c1ccc(Cl)nc1 -US20030073836A1,2,CCn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O.Cc1ccc(-c2ccc(CN)cc2)cc1>>CCn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)NCc1ccc(-c2ccc(C)cc2)cc1 -US08003649B2,1,CC(C)c1ccc(C=O)cc1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>CC(C)c1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US04169202,2,CC1(c2ccccc2)OC(C(=O)O)=CC1=O.CO>>COC(=O)C1=CC(=O)C(C)(c2ccccc2)O1 -US20150175623A1,6,CCOC(=O)[C@@H](Cc1ccccc1OCc1ccnc(-c2ccccc2OC)n1)Oc1ncnc2sc(-c3ccc(F)cc3)c(-c3ccc(OCCN4CCN(C)CC4)c(Cl)c3OCOC)c12>>CCOC(=O)[C@@H](Cc1ccccc1OCc1ccnc(-c2ccccc2OC)n1)Oc1ncnc2sc(-c3ccc(F)cc3)c(-c3ccc(OCCN4CCN(C)CC4)c(Cl)c3O)c12 -US20140186266A1,1,COc1ccc(C[C@H](C)[C@H](C)Cc2ccc(OC)c(OCCOCCOCCOCCBr)c2)cc1OC.O=[N+]([O-])c1ncc[nH]1>>COc1ccc(C[C@H](C)[C@H](C)Cc2ccc(OC)c(OCCOCCOCCOCCn3ccnc3[N+](=O)[O-])c2)cc1OC -US20100022515A1,3,C=O.CS(=O)(=O)NCCc1cccc([N+](=O)[O-])c1>>CS(=O)(=O)N1CCc2cc([N+](=O)[O-])ccc2C1 -US20050038043A1,1,CCCc1c(CBr)ncn2ncnc12.N#Cc1cccc(-c2ncc[nH]2)n1>>CCCc1c(Cn2ccnc2-c2cccc(C#N)n2)ncn2ncnc12 -US20090221555A1,1,CNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.COc1cc2c(cc1N)CCN(CCN1CCOCC1)CC2>>CNC(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(CCN2CCOCC2)CC3)ncc1Cl -US06924300B2,1,CN(CCO)c1ncccn1.O=Cc1ccc(F)cc1>>CN(CCOc1ccc(C=O)cc1)c1ncccn1 -US04695575,7,N#CCCCN1CCC(Cc2nc3ccccc3n2Cc2ccco2)CC1>>NCCCCN1CCC(Cc2nc3ccccc3n2Cc2ccco2)CC1 -US06114330,1,Brc1ccc(Br)nc1.COCCO>>COCCOc1ccc(Br)cn1 -US08519135B2,2,Nc1cc(Cl)cnc1Sc1ccncc1.O=S(=O)(Cl)c1ccc(Cl)c(C(F)(F)F)c1>>O=S(=O)(Nc1cc(Cl)cnc1Sc1ccncc1)c1ccc(Cl)c(C(F)(F)F)c1 -US07888352B2,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3o2)CC1>>CS(=O)(=O)N1CCN(Cc2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3o2)CC1 -US07737166B2,10,Cc1c(-c2ccccc2)c(F)c2oc(C3CC3)nc2c1C#N.O=C1CCC(=O)N1Br>>N#Cc1c(CBr)c(-c2ccccc2)c(F)c2oc(C3CC3)nc12 -US20090221584A1,3,O=Cc1cc(NS(=O)(=O)c2ccc(Cl)cc2Cl)ncc1Sc1ccc(S(=O)(=O)N2CCCCC2)cc1.[Mg+]C1CC1>>O=S(=O)(Nc1cc(C(O)C2CC2)c(Sc2ccc(S(=O)(=O)N3CCCCC3)cc2)cn1)c1ccc(Cl)cc1Cl -US20040044008A1,6,COC(=O)c1cccc(CN2CCN(c3ccc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)cc3)CC2)c1>>O=C(O)c1cccc(CN2CCN(c3ccc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)cc3)CC2)c1 -US08338623B2,6,CCOC(=O)c1ncccc1NC(=O)C12CC3CC(CC1C3)C2>>O=C(O)c1ncccc1NC(=O)C12CC3CC(CC1C3)C2 -US20080064715A1,8,O=S(=O)(c1ccccc1)n1c(C(O)c2ccccc2)cc2ccncc21>>O=C(c1ccccc1)c1cc2ccncc2n1S(=O)(=O)c1ccccc1 -US07271197B2,1,CC(C)Br.OCc1ccc(O)cc1>>CC(C)Oc1ccc(CO)cc1 -US04151288,1,Clc1nc[nH]n1.NCCCN>>NCCCNc1nc[nH]n1 -US08486943B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)[C@H]1NCC[C@@H]1O>>CC(C)(C)OC(=O)N1CC[C@H](O)[C@H]1C(=O)O -US07632840B2,1,CC(C)(C)OC(=O)NC[C@H](N)C(=O)O.COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1C=O>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN[C@@H](CNC(=O)OC(C)(C)C)C(=O)O -US20140142102A1,2,CC(C)N=C=O.O=C(OCc1ccccc1)N1CCNCC1>>CC(C)NC(=O)N1CCN(C(=O)OCc2ccccc2)CC1 -US04281008,6,CCCc1c(OCc2ccccc2)ccc2c(=O)cc(CCC(=O)OCC)oc12>>CCCc1c(O)ccc2c(=O)cc(CCC(=O)OCC)oc12 -US20020077356A1,6,COc1cccc(C(C)(C)CC(O)(C(=O)Nc2ccc3c(=O)onc(C)c3c2)C(F)(F)F)c1Br>>Cc1noc(=O)c2ccc(NC(=O)C(O)(CC(C)(C)c3cccc(O)c3Br)C(F)(F)F)cc12 -US20130317057A1,7,CNC(=O)c1cccc([N+](=O)[O-])c1NC>>CNC(=O)c1cccc(N)c1NC -US20130289238A1,1,COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1.OCc1csc(-c2ccccc2)n1>>COc1cc(OCc2csc(-c3ccccc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US05807878,9,CCCSc1nc(Br)c(SC)n1COCC[Si](C)(C)C>>CCCSc1ncc(SC)n1COCC[Si](C)(C)C -US07282506B2,3,O=C(NCc1ccco1)c1ccc2cncc(Br)c2n1.O=C(O)c1ccc(B(O)O)s1>>O=C(NCc1ccco1)c1ccc2cncc(-c3ccc(C(=O)O)s3)c2n1 -US20100048610A1,9,BrC(Br)(Br)Br.CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1cccc(CO)c1>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1cccc(CBr)c1 -US07361672B2,2,CCOC(=O)CN1CCNCC1.O=C(O)Cc1csc(NC(=O)c2ccc(Cl)cc2)n1>>CCOC(=O)CN1CCN(C(=O)Cc2csc(NC(=O)c3ccc(Cl)cc3)n2)CC1 -US20020123496A1,1,BrCc1ccccc1.COc1ccc(-c2n[nH]c(=O)cc2-c2ccc(OC)c(F)c2)cc1>>COc1ccc(-c2nn(Cc3ccccc3)c(=O)cc2-c2ccc(OC)c(F)c2)cc1 -US20130085148A1,6,CC(=O)NC(C)(c1ccncc1)c1cnc(-c2ccc(F)cc2)s1>>CC(N)(c1ccncc1)c1cnc(-c2ccc(F)cc2)s1 -US06143750,1,N#Cc1ccccc1N1CCC(=O)CC1.OCC1CCCNC1>>N#Cc1ccccc1N1CCC(N2CCCC(CO)C2)CC1 -US20140155419A1,2,Cc1cc(Cl)ccc1C(N)CC(C)C.O=C(O)Cc1ccc(O)cc1>>Cc1cc(Cl)ccc1C(CC(C)C)NC(=O)Cc1ccc(O)cc1 -US20080287475A1,9,CC(N=[N+]=[N-])c1ncc(F)cn1>>CC(N)c1ncc(F)cn1 -US20060094707A1,3,CCOC(=O)C[C@H](Cc1cc(Br)c2[nH]ncc2c1COC(C)=O)C(=O)OCC.C[Sn](C)(C)C>>CCOC(=O)C[C@H](Cc1cc(C)c2[nH]ncc2c1COC(C)=O)C(=O)OCC -US07649093B2,6,CCCCCc1cc2cc(OC)ccc2c(Oc2ccc(/C=C/C(=O)O)cc2)c1-c1ccccc1>>CCCCCc1cc2cc(O)ccc2c(Oc2ccc(/C=C/C(=O)O)cc2)c1-c1ccccc1 -US20130345192A1,1,Cc1ccc(S(=O)(=O)n2ccc3c(N[C@@H]4CC[C@@H]5C[C@H](N)C(=O)N5C4)ncnc32)cc1.OB(O)c1cc(F)cc(Cl)c1>>Cc1ccc(S(=O)(=O)n2ccc3c(N[C@@H]4CC[C@@H]5C[C@H](Nc6cc(F)cc(Cl)c6)C(=O)N5C4)ncnc32)cc1 -US20070149525A1,3,Brc1cscn1.CC(C)(C)C[Zn+]>>CC(C)(C)Cc1cscn1 -US09090628B2,1,CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(Cl)cc1OCC2.OCC1CCCN1>>CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(N3CCCC3CO)cc1OCC2 -US20130345123A1,6,CC(C)(C)OC(=O)N[C@H]1CCCCN(Cc2ccccc2)C1=O>>N[C@H]1CCCCN(Cc2ccccc2)C1=O -US06504031B1,3,CC(C)C1=NCCc2ccc(Br)cc21.CN(C)C=O>>CC(C)C1=NCCc2ccc(C=O)cc21 -US07247633B2,1,C1CNCCN1.Clc1cncc(OCCCCOc2ccccc2)n1>>c1ccc(OCCCCOc2cncc(N3CCNCC3)n2)cc1 -US04153620,6,COc1c(NC(C)=O)c(OCCN2CCCCC2)c(OC)c2occc12>>COc1c(N)c(OCCN2CCCCC2)c(OC)c2occc12 -US20100280001A1,2,CCOCc1nc2c(N)nc3ccccc3c2n1CCCNCc1cccc(CC(=O)OC)c1.O=C(Cl)CCl>>CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(CC(=O)OC)c1)C(=O)CCl -US05700809,7,C(=Cc1ccco1)c1ccncc1>>c1coc(CCc2ccncc2)c1 -US04297350,7,CC=C1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](OC)[C@@]4(C)CC[C@@H]32)CC1=O>>CC[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](OC)[C@@]4(C)CC[C@@H]32)CC1=O -US20080306120A1,3,CC1(C)OB(c2ccnc3c2ccn3S(=O)(=O)c2ccccc2)OC1(C)C.CN(C)CCn1cc(Br)c(-c2ccc([N+](=O)[O-])cc2)n1>>CN(C)CCn1cc(-c2ccnc3c2ccn3S(=O)(=O)c2ccccc2)c(-c2ccc([N+](=O)[O-])cc2)n1 -US08946216B2,6,CC(c1ccccc1)N1CCC[C@H](C(=O)OC(C)(C)C)C1>>CC(c1ccccc1)N1CCC[C@H](C(=O)O)C1 -US20100216802A1,2,CC(C)(C)OC(=O)N[C@@H](CCN)C(=O)OC1CCCC1.CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)O)cc3OC)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC4CCCC4)cc3OC)nc2N1C1CCCC1 -US20150133449A1,9,COC(=O)c1ccc2ncccc2c1.N>>NC(=O)c1ccc2ncccc2c1 -US20130274494A1,6,CCCCCCCC/C=C\CCCCCCCC(=O)OC>>CCCCCCCC/C=C\CCCCCCCC(=O)O -US04873236,2,NCCN1CCC(CNCC2CCCCC2)C1.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>O=C1Nc2cccnc2N(C(=O)NCCN2CCC(CNCC3CCCCC3)C2)c2ccccc21 -US08188111B2,2,CCOC(=O)Cl.CCc1nc2c(N)nc3ccccc3c2n1CCCCNS(C)(=O)=O>>CCOC(=O)Nc1nc2ccccc2c2c1nc(CC)n2CCCCNS(C)(=O)=O -US20150232460A1,2,CC1(Nc2ncc(C(F)(F)F)cc2F)CCCC1N.O=C(O)c1ncccc1-c1ncccn1>>CC1(Nc2ncc(C(F)(F)F)cc2F)CCCC1NC(=O)c1ncccc1-c1ncccn1 -US04503063,9,CCOC(=O)C(C)(C)C(O)(Cn1cncn1)c1ccc(Cl)cc1Cl.N>>CC(C)(C(N)=O)C(O)(Cn1cncn1)c1ccc(Cl)cc1Cl -US20080021056A1,2,CCOC(=O)CCNc1cccc(F)c1.O=S(=O)(Cl)c1ccc(Cl)cc1>>CCOC(=O)CCN(c1cccc(F)c1)S(=O)(=O)c1ccc(Cl)cc1 -US07465731B2,1,CCOC(=O)/C=C/c1ccc(Cl)nc1.N[C@@H]1CCN(Cc2ccccc2)C1>>CCOC(=O)/C=C/c1ccc(N[C@@H]2CCN(Cc3ccccc3)C2)nc1 -US08129403B2,7,C[C@H](Nc1cc(Nc2cc(C3CC3)[nH]n2)c([N+](=O)[O-])cc1C#N)c1ccc(F)cc1>>C[C@H](Nc1cc(Nc2cc(C3CC3)[nH]n2)c(N)cc1C#N)c1ccc(F)cc1 -US06437138B1,3,C=C[Sn](CCCC)(CCCC)CCCC.CC(C)(C)OC(=O)N1CCC[C@H]1COc1cnc(Cl)c(Br)c1>>C=Cc1cc(OC[C@@H]2CCCN2C(=O)OC(C)(C)C)cnc1Cl -US20130178443A1,1,FC1(F)CCNC1.Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3ccccc3C=O)ccc2n1>>Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3ccccc3CN3CCC(F)(F)C3)ccc2n1 -US20080161366A1,1,CN.Cc1c(F)cccc1N1c2ccccc2N(CCCBr)S1(=O)=O>>CNCCCN1c2ccccc2N(c2cccc(F)c2C)S1(=O)=O -US05152919,1,CCCCCCCCOc1ccc(-c2ccc(Cl)nn2)cc1.CCCO[C@@H](C)CC[C@H](C)O>>CCCCCCCCOc1ccc(-c2ccc(O[C@@H](C)CC[C@H](C)OCCC)nn2)cc1 -US03987088,3,CC(=O)OC(C)=O.CC(=O)c1cccc2c1-c1ccccc1C2>>CC(=O)c1ccc2c(c1)Cc1cccc(C(C)=O)c1-2 -US20100152458A1,3,Clc1ccccc1-c1nnn(C2CCCCO2)n1.[Mg+]c1ccc(COC2CCCCO2)cc1>>c1ccc(-c2nnn(C3CCCCO3)n2)c(-c2ccc(COC3CCCCO3)cc2)c1 -US20110212053A1,3,CC(C)(C#N)c1ccc(Cc2c([N+](=O)[O-])cnc3ccc(B4OC(C)(C)C(C)(C)O4)cc23)cc1.COc1cccc(Br)n1>>COc1cccc(-c2ccc3ncc([N+](=O)[O-])c(Cc4ccc(C(C)(C)C#N)cc4)c3c2)n1 -US04701552,3,CC1(C)CCC(C)(C)C1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.NC(C=O)(C(=O)OCc1ccccc1)C(=O)OCc1ccccc1>>CC1(C)CCC(C)(C)C1C=CC(N)(C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 -US20110028492A1,1,Fc1cc(-c2nc(NCC3CCOCC3)ccc2Cl)c(Cl)cn1.N[C@H]1CC[C@H](N)CC1>>N[C@@H]1CC[C@@H](Nc2cc(-c3nc(NCC4CCOCC4)ccc3Cl)c(Cl)cn2)CC1 -US08273740B2,2,CCCCC(=O)Cl.ClCCCNCCc1ccccc1>>CCCCC(=O)N(CCCCl)CCc1ccccc1 -US20090156578A1,2,CNCc1c(C)c2ccccc2n1C.O=C(O)/C=C/c1cnc2c(c1)OCC(=O)N2>>Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)OCC(=O)N3)n(C)c2ccccc12 -US20140155389A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(N2CCNCC2)cc1Cl>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)c(Cl)c2)CC1 -US06582351B1,7,COC(=O)c1ccc(OC)c(C#N)c1>>COc1ccc(CO)cc1C#N -US20140200344A1,2,Cc1cc(N)sn1.O=C(Cl)Oc1ccccc1>>Cc1cc(NC(=O)Oc2ccccc2)sn1 -US20040192734A1,6,CC(C)(C)OC(=O)NCc1cccc(C2CCN(C(=O)c3ccc(C#Cc4ccccc4F)o3)CC2)c1>>NCc1cccc(C2CCN(C(=O)c3ccc(C#Cc4ccccc4F)o3)CC2)c1 -US20070123532A1,1,COCCOCCl.Cc1ccc(C[C@@H]2CN(Cc3ccccc3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1O>>COCCOCOc1cc(C[C@@H]2CN(Cc3ccccc3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)ccc1C -US05744604,6,COC(=O)C[C@@H](CC(=O)/C=C/c1ccc(Cl)cc1Cl)O[Si](C)(C)C(C)(C)C>>COC(=O)C[C@H](O)CC(=O)/C=C/c1ccc(Cl)cc1Cl -US20100093757A1,1,Cc1ccc(NC(=O)[C@@H](O)COC(C)C)nc1.Cc1cnccc1-n1ncc2c(Cl)ncnc21>>Cc1ccc(NC(=O)[C@H](COC(C)C)Oc2ncnc3c2cnn3-c2ccncc2C)nc1 -US07585886B2,6,CC(C)(C)[Si](C)(C)OCC1CCN(C(=O)C(F)(F)F)C1>>O=C(N1CCC(CO)C1)C(F)(F)F -US04263207,6,COC(=O)c1ccc2c(c1)Sc1ccccc1NC2=O>>O=C(O)c1ccc2c(c1)Sc1ccccc1NC2=O -US20020028814A1,7,CCC(C)(C)C(=O)C(=O)C1CCCNN1C(=O)CCCC#Cc1cccnc1>>CCC(C)(C)C(=O)C(=O)C1CCCNN1C(=O)CCCCCc1cccnc1 -US20150038460A1,8,CN1CCCC(O)C1=O>>CN1CCCC(=O)C1=O -US08946197B2,7,O=C(OCc1ccccc1)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1>>Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3)CC2)cc1 -US20040006141A1,2,CC(C)c1ccc(OCC(=O)O)cc1.O=C1N[C@H](Cc2ccccc2)CO1>>CC(C)c1ccc(OCC(=O)N2C(=O)OC[C@H]2Cc2ccccc2)cc1 -US04785010,4,CC(=O)CCC(=O)CN1C(=O)c2ccccc2C1=O.CCOC(=O)CCCN>>CCOC(=O)CCCn1c(C)ccc1CN1C(=O)c2ccccc2C1=O -US04423047,8,CSc1ncc(Cl)cn1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ncc(Cl)cn1 -US04175189,1,C1=CCNCC1.COC(=O)Nc1cc(Cl)nc(NC(=O)OC)[n+]1[O-]>>COC(=O)Nc1cc(N2CC=CCC2)nc(NC(=O)OC)[n+]1[O-] -US20040116464A1,7,CN(CC(=O)c1ccc(Br)cc1)C(=O)OC(C)(C)C>>CN(CC(O)c1ccc(Br)cc1)C(=O)OC(C)(C)C -US20130331378A1,3,COC(=O)c1cc(C)cc(CBr)c1.COc1ccc2c(Br)c(-c3ccccc3)nn2c1[Si](C)(C)C>>COC(=O)c1cc(C)cc(Cc2c(-c3ccccc3)nn3c([Si](C)(C)C)c(OC)ccc23)c1 -US20110144105A1,7,CCOc1ccc(C(=CC2CCCC2)c2cc3cccnc3[nH]2)cn1>>CCOc1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cn1 -US20140288123A1,1,CCC(O)c1ccc(Br)cc1.Oc1ccccc1>>CCC(Oc1ccccc1)c1ccc(Br)cc1 -US07932281B2,1,CCCN(CCC)Cc1cccc(C(=O)N(C)c2cc(C(=O)OC)ccc2N)c1>>CCCN(CCC)Cc1cccc(-c2nc3ccc(C(=O)OC)cc3n2C)c1 -US20140100231A1,6,COc1ccc(Cn2nc(Cn3cnc(C(F)(F)F)c(Oc4cc(Cl)cc(C#N)c4)c3=O)cc(-c3ccccc3)c2=O)cc1>>N#Cc1cc(Cl)cc(Oc2c(C(F)(F)F)ncn(Cc3cc(-c4ccccc4)c(=O)[nH]n3)c2=O)c1 -US20150175602A1,2,CC(C)Nc1nc2c(nc1N1CCC(C(=O)c3cc(Cl)ccc3F)CC1)CNCC2.CN(C)C(=O)Cl>>CC(C)Nc1nc2c(nc1N1CCC(C(=O)c3cc(Cl)ccc3F)CC1)CN(C(=O)N(C)C)CC2 -US20070032502A1,1,CN(C)CCCNc1nc(CN2CCNCC2)nc2ccccc12.Clc1ccc(C(Cl)c2ccc(Cl)cc2)cc1>>CN(C)CCCNc1nc(CN2CCN(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)CC2)nc2ccccc12 -US20150111870A1,2,COC(=O)c1cc(Br)ccc1N.O=C(Br)CBr>>COC(=O)c1cc(Br)ccc1NC(=O)CBr -US20140171429A1,7,COc1cc(C(=O)N2CCN(C)CC2)ccc1[N+](=O)[O-]>>COc1cc(C(=O)N2CCN(C)CC2)ccc1N -US07507740B2,1,CCOCCBr.Clc1ncnc2cc(-c3ccco3)[nH]c12>>CCOCCn1c(-c2ccco2)cc2ncnc(Cl)c21 -US07361678B2,1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccc2oc3ccccc3c2c1>>O=[N+]([O-])c1ccc(Oc2ccc3oc4ccccc4c3c2)cc1 -US20070082912A1,2,CC(=O)OC(C)=O.Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1cccc(S(N)(=O)=O)c1>>CC(=O)NS(=O)(=O)c1cccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2F)c1 -US20030191132A1,6,CC(C)(C)OC(=O)N1CCC(COc2ccc(F)cc2)CC1>>Fc1ccc(OCC2CCNCC2)cc1 -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1.COc1ccc(C(=O)CCCCCBr)cc1>>COc1ccc(C(=O)CCCCCN2CCC(CNC(=O)c3cc(Cl)c(N)cc3OC)CC2)cc1 -US20060025327A1,1,Clc1ccc2c(Cl)ccnc2c1.NCCC(=O)O>>O=C(O)CCNc1ccnc2cc(Cl)ccc12 -US05118599,7,COc1ccc([N+](=O)[O-])cc1NC(=O)CC(=O)C1(C)COC(C)(C)OC1>>COc1ccc(N)cc1NC(=O)CC(=O)C1(C)COC(C)(C)OC1 -US05216026,2,CCC(C)S(N)(=O)=O.O=C=Nc1ccc(Br)cc1>>CCC(C)S(=O)(=O)NC(=O)Nc1ccc(Br)cc1 -US04505898,2,C=CCOc1ccc(C[C@H](NC(=O)Cc2ccccc2)C(=O)O)cc1Cl.COC(=O)[C@@H](N)Cc1ccccc1>>C=CCOc1ccc(C[C@H](NC(=O)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)OC)cc1Cl -US20030171592A1,7,N#CCC(=O)c1ccccc1>>N#CC[C@H](O)c1ccccc1 -US20070117798A1,7,C[C@H]1CN([C@@H](c2cc(F)c(F)c(F)c2)[C@H](CO[SiH](c2ccccc2)c2ccccc2)C(C)(C)C)C(=O)C(=O)O1>>CC1CN([C@@H](c2cc(F)c(F)c(F)c2)[C@H](CO[SiH](c2ccccc2)c2ccccc2)C(C)(C)C)C(=O)[C@@H](O)O1 -US08748434B2,6,COC(=O)c1cc(Cl)cc(S(C)(=O)=O)c1>>CS(=O)(=O)c1cc(Cl)cc(C(=O)O)c1 -US20050165032A1,1,Clc1ncnc2c1CCN(Cc1ccccc1)C2.Nc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(Nc2ncnc3c2CCN(Cc2ccccc2)C3)cc1 -US08937091B2,3,O=C(Cl)C=Cc1ccccc1.c1ccc2ccccc2c1>>O=C(C=Cc1ccccc1)c1ccc2ccccc2c1 -US20110245257A1,6,COC(=O)c1cccc2nc([C@H](C)NC(=O)OCc3ccccc3)c(-c3cccnc3)n12>>COC(=O)c1cccc2nc([C@H](C)N)c(-c3cccnc3)n12 -US20100075983A1,7,COC(=O)C=C1CC(COCc2ccccc2)C1>>COC(=O)CC1CC(COCc2ccccc2)C1 -US20030073862A1,2,COC(=O)c1cc(OCCOCCN)ccc1NC(=O)c1ccc(Cl)cc1Cl.O=C=Nc1ccc(F)cc1F>>COC(=O)c1cc(OCCOCCNC(=O)Nc2ccc(F)cc2F)ccc1NC(=O)c1ccc(Cl)cc1Cl -US06380249B1,6,CCOC(=O)C(=O)CC(=O)c1cccc(C2CCCc3ccccc32)c1>>O=C(O)C(=O)CC(=O)c1cccc(C2CCCc3ccccc32)c1 -US05076833,1,CCC(CC)c1nnc(SC)n(N)c1=O.CI>>CCC(CC)c1nnc(SC)n(NC)c1=O -US20120309738A1,2,CC(C)(C)C(=O)Cl.NCc1ccc(OC(F)(F)F)cc1>>CC(C)(C)C(=O)NCc1ccc(OC(F)(F)F)cc1 -US20100292210A1,1,C=O.Clc1ccc2c(n1)O[C@H](c1ccccc1)CNC2>>CN1Cc2ccc(Cl)nc2O[C@H](c2ccccc2)C1 -US05480873,4,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].COc1cccc2c1C(=O)c1c(OC)cc(C#N)cc1C2=O>>COc1cccc2c1C(=O)c1c(OC)cc(-c3nnn[nH]3)cc1C2=O -US20150246912A1,7,COC(=O)C(C)(C)n1cc(I)c2cnccc21>>CC(C)(CO)n1cc(I)c2cnccc21 -US20110263598A1,3,C=CB1OC(C)CC(C)(C)O1.F[C@@H]1CCN(Cc2ccc(Br)cc2)C1>>CC1CC(C)(C)OB(/C=C/c2ccc(CN3CC[C@@H](F)C3)cc2)O1 -US20050054671A1,1,COC(=O)C(C)(C)Sc1cccc(O)c1.OCCn1ccc2ccccc21>>COC(=O)C(C)(C)Sc1cccc(OCCn2ccc3ccccc32)c1 -US20090286778A1,2,O=C(CC1CCNCC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2.O=C(O)c1ccns1>>O=C(CC1CCN(C(=O)c2ccns2)CC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2 -US20090005379A1,1,C[C@H]1CCCN1.O=C(c1cc2cc(OCCCCl)cnc2[nH]1)N1CCC(F)(F)CC1>>C[C@H]1CCCN1CCCOc1cnc2[nH]c(C(=O)N3CCC(F)(F)CC3)cc2c1 -US20150238601A1,1,Cc1cnc(Cl)nc1Cl.Nc1ccc2[nH]ncc2c1>>Cc1cnc(Cl)nc1Nc1ccc2[nH]ncc2c1 -US06713474B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(CO)cc1>>CC(C)(C)OC(=O)Nc1ccc(CO)cc1 -US20140148443A1,2,CCOc1cc(Cl)c(S(C)(=O)=O)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.O=C1CNCCN1>>CCOc1cc(Cl)c(S(C)(=O)=O)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCNC(=O)C1 -US08288538B2,2,NC(=O)c1cc(Oc2ccc(N)c(F)c2)ccn1.O=C(O)C1(C(=O)Nc2ccc(F)cc2)CC1>>NC(=O)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1 -US08367697B2,3,CC1(C)OB(c2ccc3c(c2)C(=O)CC3)OC1(C)C.Ic1ccnc2[nH]ncc12>>O=C1CCc2ccc(-c3ccnc4[nH]ncc34)cc21 -US20120184562A1,2,CN1CCN(c2ccc3cc(C(=O)O)c(=O)[nH]c3n2)CC1.COC(=O)c1cccc(N)c1>>COC(=O)c1cccc(NC(=O)c2cc3ccc(N4CCN(C)CC4)nc3[nH]c2=O)c1 -US20150087631A1,1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.O[C@@H]1CCCNC1>>c1ccc2oc(-c3cnc4ccc(O[C@@H]5CCCNC5)nn34)cc2c1 -US04343945,2,COc1ccc(C(=O)Cl)cc1.Nc1nc(C(Cl)(Cl)Cl)ns1>>COc1ccc(C(=O)Nc2nc(C(Cl)(Cl)Cl)ns2)cc1 -US07863332B2,8,OCc1ccc(I)c(OCc2ccccc2)c1>>O=Cc1ccc(I)c(OCc2ccccc2)c1 -US20130029962A1,6,CCOC(=O)C(C)c1ccc(C#N)nc1>>CC(C(=O)O)c1ccc(C#N)nc1 -US08063099B2,2,COc1ccc(C(=O)O)c(OC)c1.Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c1>>COc1ccc(C(=O)NC[C@@H]2[C@H]3C[C@H]3CN2C(=O)c2nc(C)sc2-c2cccc(C)c2)c(OC)c1 -US20110152095A1,7,CCc1ccc(Br)cc1[N+](=O)[O-]>>CCc1ccc(Br)cc1N -US08163737B2,4,O=C(OCc1ccccc1)N1CCC2(CC1)CC(=NO)c1ccccc12>>O=C1CC2(CCN(C(=O)OCc3ccccc3)CC2)c2ccccc2N1 -US20060270692A1,1,CC(C)(C)C(=O)OCn1cnc2cc(OCc3ccccc3)cc(O)c2c1=O.CC(C)O>>CC(C)Oc1cc(OCc2ccccc2)cc2ncn(COC(=O)C(C)(C)C)c(=O)c12 -US04525478,6,CCOC(=O)C1=C(C)NC(C(OCC)OCC)=C(C(=O)OCC)C1c1ccccc1[N+](=O)[O-]>>CCOC(=O)C1=C(C)NC(C=O)=C(C(=O)OCC)C1c1ccccc1[N+](=O)[O-] -US04029780,1,C1CNCCN1.O=S1(=O)NC(Cl)=Nc2ccc(Cl)cc21>>O=S1(=O)NC(N2CCNCC2)=Nc2ccc(Cl)cc21 -US20130274260A1,1,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CCl)c1.c1c[nH]cn1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cn2ccnc2)c1 -US20110124668A1,2,CC(=O)O.NC(=O)Nc1[nH]c2cc(Oc3ccc(N)cc3)ccc2c1C(N)=O>>CC(=O)Nc1ccc(Oc2ccc3c(C(N)=O)c(NC(N)=O)[nH]c3c2)cc1 -US07153862B2,3,COP(=O)(CC(=O)CCCCCNC(=O)OC(C)(C)C)OC.Cc1ncc(C=O)cn1>>Cc1ncc(C=CC(=O)CCCCCNC(=O)OC(C)(C)C)cn1 -US20070082896A1,6,CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](Nc2nc(OCc3ccc(OC)cc3)ncc2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](Nc2nc(O)ncc2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC -US04088772,7,CC(=O)c1ccc2c(c1)C13CC2c2ccccc2C1CN(CC1CCCC1)C3>>CC(O)c1ccc2c(c1)C13CC2c2ccccc2C1CN(CC1CCCC1)C3 -US20060183758A1,3,C#CCc1ccccc1.Nc1ncccc1I>>Nc1ncccc1C#CCc1ccccc1 -US07381728B2,3,O=S(=O)(Oc1ccccc1)c1cccc(Br)n1.OB(O)c1ccsc1>>O=S(=O)(Oc1ccccc1)c1cccc(-c2ccsc2)n1 -US20050154230A1,2,Nc1ccccc1CCO.O=C=Nc1ccc(Cl)c(Cl)c1>>O=C(Nc1ccc(Cl)c(Cl)c1)Nc1ccccc1CCO -US20030069419A1,1,CC(C)(C)Oc1ccc(CCCCCl)cc1.c1c[nH]nn1>>CC(C)(C)Oc1ccc(CCCCn2ccnn2)cc1 -US08198454B2,1,CC(C)c1ccc(N(Cc2cn[nH]c2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1.Cc1ccnc(CCl)c1>>Cc1ccnc(Cn2cc(CN(C(=O)C3CCCc4c(OCc5ccccc5)cccc43)c3ccc(C(C)C)nc3)cn2)c1 -US05650428,2,CCOC(=O)Cc1ccc(N)cc1.O=C(O)[C@@H](Cc1ccccc1)NS(=O)(=O)c1ccc(Br)cc1>>CCOC(=O)Cc1ccc(NC(=O)[C@@H](Cc2ccccc2)NS(=O)(=O)c2ccc(Br)cc2)cc1 -US20100063108A1,2,Cc1cc(-c2nc(-c3ccc(CC(=O)O)cc3)no2)cc(CC(C)C)n1.NCCO>>Cc1cc(-c2nc(-c3ccc(CC(=O)NCCO)cc3)no2)cc(CC(C)C)n1 -US20100069630A1,1,CC(C)(C)OC(=O)NC1CCNCC1.CI>>CN1CCC(NC(=O)OC(C)(C)C)CC1 -US20140329863A1,4,Cc1cccc(NC(N)=S)n1.O=C(CBr)c1ccc(Br)cc1>>Cc1cccc(Nc2nc(-c3ccc(Br)cc3)cs2)n1 -US08497264B2,3,NC1=N[C@@]2(COC1)c1cc(-c3cccnc3F)ccc1Oc1cnc(Cl)cc12.OB(O)C1=CCOCC1>>NC1=N[C@@]2(COC1)c1cc(-c3cccnc3F)ccc1Oc1cnc(C3=CCOCC3)cc12 -US20040072818A1,1,CI.O=C(NC1CCCCC(O)C1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1>>COC1CCCCC(NC(=O)N2CCN(c3ccnc4cc(Cl)ccc34)CC2)C1 -US07919502B2,1,CC(Br)c1c(F)ccc(F)c1Cl.O=C1CNc2ncc(I)cc2N1>>CC(c1c(F)ccc(F)c1Cl)N1C(=O)CNc2ncc(I)cc21 -US06137007,1,N[C@H]1C=C[C@@H](CO)C1.Nc1nc(Cl)c(NC=O)c(Cl)n1>>Nc1nc(Cl)c(NC=O)c(N[C@H]2C=C[C@@H](CO)C2)n1 -US20110130383A1,7,O=C(OCc1ccccc1)N1CCc2ccc([N+](=O)[O-])cc2CC1>>Nc1ccc2c(c1)CCN(C(=O)OCc1ccccc1)CC2 -US08809525B2,3,Nc1nnc(Br)c(-c2ccccc2)n1.OB(O)c1ccc(Cl)c(Cl)c1>>Nc1nnc(-c2ccc(Cl)c(Cl)c2)c(-c2ccccc2)n1 -US20090221555A1,1,CNC(=O)c1cc(F)cc(F)c1Nc1nc(Cl)ncc1Cl.Nc1ccc2c(c1)NC(=O)CCC2>>CNC(=O)c1cc(F)cc(F)c1Nc1nc(Nc2ccc3c(c2)NC(=O)CCC3)ncc1Cl -US20080275069A1,2,CN.Nc1cc(Br)cnc1C(=O)O>>CNC(=O)c1ncc(Br)cc1N -US20100324057A1,1,FC(F)(F)c1cccc(S)c1.O=Cc1ccc(Br)cc1F>>O=Cc1ccc(Sc2cccc(C(F)(F)F)c2)cc1F -US20090137580A1,2,Cn1ccc2ncnc(Oc3ccc(C(=O)O)cc3)c21.Nc1ccccc1>>Cn1ccc2ncnc(Oc3ccc(C(=O)Nc4ccccc4)cc3)c21 -US08071588B2,6,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)CCC(=O)OC>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)CCC(=O)O -US05426188,1,CCCCOC(=O)Cl.N=C1SCCN1c1cccc(C(F)(F)F)c1>>CCCCOC(=O)N=C1SCCN1c1cccc(C(F)(F)F)c1 -US20070244164A1,1,Nc1ccc(I)cc1F.O=c1cc(Cl)c([N+](=O)[O-])c[nH]1>>O=c1cc(Nc2ccc(I)cc2F)c([N+](=O)[O-])c[nH]1 -US07759501B2,3,C=O.CC(=O)c1cccs1.CNC>>CN(C)CCC(=O)c1cccs1 -US20100204196A1,7,COc1cc(N2CCN(CC3CC3)CC2)ccc1[N+](=O)[O-]>>COc1cc(N2CCN(CC3CC3)CC2)ccc1N -US08691854B2,1,COc1ccccc1C=CC=O.NNC(N)=S>>COc1ccccc1C=CC=NNC(N)=S -US20050043300A1,6,COc1cc2c(cc1OC)C(=O)NCC2>>COc1cc2c(cc1O)CCNC2=O -US04152442,2,CC(C)C(=O)OC(=O)C(C)C.Cc1nnc(N)s1>>Cc1nnc(NC(=O)C(C)C)s1 -US20120040998A1,9,C[C@H]1CC[C@@H](C(N)=O)CN1C(=O)OC(C)(C)C>>C[C@H]1CC[C@@H](C#N)CN1C(=O)OC(C)(C)C -US07915411B2,7,O=[N+]([O-])c1cc(COc2cccc(Br)c2)ccc1Sc1ccc(O)cc1>>Nc1cc(COc2cccc(Br)c2)ccc1Sc1ccc(O)cc1 -US20100274051A1,2,Nc1cc(Cl)cc(Cl)c1.O=C(O)c1cc2ccccc2cc1O>>O=C(Nc1cc(Cl)cc(Cl)c1)c1cc2ccccc2cc1O -US20120094997A1,1,COC(=O)c1ccc2c(=O)n(-c3ccccc3)c(Cl)nc2c1.NCc1ccc(Cl)cc1>>COC(=O)c1ccc2c(=O)n(-c3ccccc3)c(NCc3ccc(Cl)cc3)nc2c1 -US20100274013A1,7,CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)N[C@H](CO)CC(=O)OCc1ccccc1 -US20100075953A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1cccc2ccccc12>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc3ccccc23)CC1 -US20090099231A1,2,CC1c2ccc(N3CC[C@H](N)C3=O)cc2CCN1C(=O)OC(C)(C)C.O=S(=O)(Cl)/C=C/c1ccc(Cl)s1>>CC1c2ccc(N3CC[C@H](NS(=O)(=O)/C=C/c4ccc(Cl)s4)C3=O)cc2CCN1C(=O)OC(C)(C)C -US20080032998A1,3,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.OB(O)c1cccnc1>>CC(C)(C)OC(=O)N1CC=C(c2cccnc2)CC1 -US20090182029A1,2,COC(=O)CCCCCN.O=C1Nc2ccc(F)cc2C1=NN=Cc1ccc(C(=O)O)cc1>>COC(=O)CCCCCNC(=O)c1ccc(C=NN=C2C(=O)Nc3ccc(F)cc32)cc1 -US08148383B2,1,CC(C)(C)OC(=O)CBr.CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)[nH]c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC(=O)OC(C)(C)C)c2ncnn12 -US06150363,1,Nc1ccccc1C(=O)O.O=C(c1ccccc1)c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(c1ccccc1)c1ccc(Nc2ccccc2C(=O)O)c([N+](=O)[O-])c1 -US20060051710A1,1,CCCCCC(=O)OCC1(C)CN(c2ccccc2)NC1=O.O=C(Cl)Cl>>CCCCCC(=O)OCC1(C)CN(c2ccccc2)N(C(=O)Cl)C1=O -US20030166694A1,1,CNCC(=O)O.N#Cc1cccc(I)c1>>CN(CC(=O)O)c1cccc(C#N)c1 -US06903086B2,6,COC(=O)c1cc(-c2ccccc2)ccc1NC(=O)OCc1ccc(-c2ccccc2)cc1>>O=C(Nc1ccc(-c2ccccc2)cc1C(=O)O)OCc1ccc(-c2ccccc2)cc1 -US05211879,1,CCCC(C)(F)C(=O)O.CCCCOc1ccc(-c2ncc(-c3ccc(O)cc3)cn2)cc1>>CCCCOc1ccc(-c2ncc(-c3ccc(OC(=O)C(C)(F)CCC)cc3)cn2)cc1 -US20050182040A1,6,CCCOc1cc(NC2CCN(Cc3ccccc3)CC2)ccc1C(N)=O>>CCCOc1cc(NC2CCNCC2)ccc1C(N)=O -US20120053180A1,2,CS(=O)(=O)Cl.CS(=O)(=O)c1ccc(-c2cc(F)c(OC3CCC(O)CC3)c(F)c2)cc1>>CS(=O)(=O)OC1CCC(Oc2c(F)cc(-c3ccc(S(C)(=O)=O)cc3)cc2F)CC1 -US06841556B2,7,COC(=O)c1n[nH]c2c1nc(-c1ccccc1)c1ccccc12>>OCc1n[nH]c2c1nc(-c1ccccc1)c1ccccc12 -US05886025,3,COc1ccc(-c2cc3ccc(OC)cc3s2)cc1.COc1cccc(OC)c1C(=O)Cl>>COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2c(OC)cccc2OC)cc1 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1cccc(Oc2cccc(C(F)(F)F)c2)c1>>FC(F)(F)c1cccc(Oc2cccc(CNc3cccc(-c4c(Cc5ccccc5)cnc5c(C(F)(F)F)cccc45)c3)c2)c1 -US20040122057A1,7,CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(-c2ccccc2C=O)cc1F>>CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(-c2ccccc2CO)cc1F -US20100234351A1,6,CC(C)(C)OC(=O)NCCS(=O)(=O)C(C)(C)C>>CC(C)(C)S(=O)(=O)CCN -US20100256134A1,1,CCOC(=O)c1cnn2c(Cl)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12.Nc1ccc2[nH]ccc2c1>>CCOC(=O)c1cnn2c(Nc3ccc4[nH]ccc4c3)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12 -US08569535B2,2,CCOC(=O)C1(N)[C@@H](C)c2ccccc2[C@H]1C.O=C(O)c1cccc2c1CCCC2>>CCOC(=O)C1(NC(=O)c2cccc3c2CCCC3)[C@@H](C)c2ccccc2[C@H]1C -US07737141B2,6,CC(=O)[C@H]1COC[C@@H](c2cc(F)c(F)c(F)c2)N1C(=O)OCc1ccccc1>>CC(=O)[C@H]1COC[C@@H](c2cc(F)c(F)c(F)c2)N1 -US09089569B2,3,CCC(CC)(Cc1nc2ccc(OCc3ccn(C)n3)cc2n1Cc1ccc(Br)cc1F)C(=O)O.OB(O)c1ccc(C(F)(F)F)cc1>>CCC(CC)(Cc1nc2ccc(OCc3ccn(C)n3)cc2n1Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1F)C(=O)O -US20040063691A1,1,CI.O=C(NC1CCNCC1)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1>>CN1CCC(NC(=O)c2cn(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)n2)CC1 -US06881844B2,1,CC(C)I.O=C(c1c[nH]c2cc(Cl)ccc12)C(F)(F)F>>CC(C)n1cc(C(=O)C(F)(F)F)c2ccc(Cl)cc21 -US20050026925A1,7,CCOc1cnc2c(c1)cc1n2[C@H](C)CN(C(=O)OC(C)(C)C)C1>>CCOc1cnc2c(c1)C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N21 -US20110098275A1,2,C1CN(C2CCOCC2)CCN1.CCc1nccc(-c2ccc(C(=O)O)c(F)c2)c1C#Cc1ccc(NC)nc1>>CCc1nccc(-c2ccc(C(=O)N3CCN(C4CCOCC4)CC3)c(F)c2)c1C#Cc1ccc(NC)nc1 -US04478837,1,C=CCCC(=O)N1CCc2nnc(Cl)cc2C1.CNN>>C=CCCC(=O)N1CCc2nnc(N(C)N)cc2C1 -US06048900,1,O=C(CBr)Nc1ccc(C2CCCCC2)cc1.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=C(CN1CCC(n2c(=O)[nH]c3ccccc32)CC1)Nc1ccc(C2CCCCC2)cc1 -US05393735,1,ClCSc1ccccc1.O=C1CC(C(F)(F)F)CC(=O)N1c1cc(O)c(Cl)cc1F>>O=C1CC(C(F)(F)F)CC(=O)N1c1cc(OCSc2ccccc2)c(Cl)cc1F -US20070010537A1,7,O=c1[nH]c2cccc([N+](=O)[O-])c2c(=O)n1-c1cccc(S(=O)(=O)N2CCCc3ccccc32)c1>>Nc1cccc2[nH]c(=O)n(-c3cccc(S(=O)(=O)N4CCCc5ccccc54)c3)c(=O)c12 -US08673906B2,1,CC(Br)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12.Cc1ccc(C#N)cc1N>>Cc1ccc(C#N)cc1NC(C)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 -US20130012523A1,1,COC(=O)c1ccc(C)c(-n2cc(Br)nc(Br)c2=O)c1.NC1(c2ccccc2OCc2ccccc2)CCC1>>COC(=O)c1ccc(C)c(-n2cc(Br)nc(NC3(c4ccccc4OCc4ccccc4)CCC3)c2=O)c1 -US08461175B2,1,C[Si](C)(C)CCOCCl.Fc1cccc(F)c1-c1nc2c(Br)n[nH]c2c2ccc(I)cc12>>C[Si](C)(C)CCOCn1nc(Br)c2nc(-c3c(F)cccc3F)c3cc(I)ccc3c21 -US06486098B1,1,CC(Br)C(=O)N(C)c1ccccc1F.Oc1ccc(O)cc1>>CC(Oc1ccc(O)cc1)C(=O)N(C)c1ccccc1F -US06900224B2,1,BrCc1ccccc1.C#CCNC[C@H](C=C)NC(=O)OC(C)(C)C>>C#CCN(Cc1ccccc1)C[C@H](C=C)NC(=O)OC(C)(C)C -US20070042974A1,2,CCOC(=O)Cl.NCCC[C@@H](O)C(=O)O>>CCOC(=O)NCCC[C@@H](O)C(=O)O -US06096743,1,CC(C)(C)OC(=O)CNc1cc(F)c(C(F)(F)F)cc1[N+](=O)[O-].c1c[nH]cn1>>CC(C)(C)OC(=O)CNc1cc(-n2ccnc2)c(C(F)(F)F)cc1[N+](=O)[O-] -US20060173058A1,1,CCCCCCCCBr.O=C(Nc1ccc(O)cc1O)C(F)(F)F>>CCCCCCCCOc1ccc(NC(=O)C(F)(F)F)c(O)c1 -US07786114B2,1,CN1CCN(c2ccc(CN)cc2)CC1.COc1cc2c(nc1OC)c(-c1cc3c(C=O)ccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2C>>COc1cc2c(nc1OC)c(-c1cc3c(CNCc4ccc(N5CCN(C)CC5)cc4)ccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2C -US05786367,1,C=CCOc1ccc2c(c1)CCC(=O)N2.CC(C)=CCBr>>C=CCOc1ccc2c(c1)CCC(=O)N2CC=C(C)C -US09139559B2,1,CCOC(=O)CN.Clc1nccnc1Cl>>CCOC(=O)CNc1nccnc1Cl -US08618137B2,2,CC1=NN(CC(=O)O)C(C)C1.Fc1cccc(F)c1C1CC(c2csc(C3CCNCC3)n2)=NO1>>CC1=NN(CC(=O)N2CCC(c3nc(C4=NOC(c5c(F)cccc5F)C4)cs3)CC2)C(C)C1 -US07629458B2,1,CN1CCNCC1.C[C@H]1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23>>C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 -US20090227560A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1CCOc1ccc2c(c1)CCC(=O)N2.COCCCBr>>COCCCN1C(=O)CCc2cc(OCC[C@@H]3CN(C(=O)OCc4ccccc4)CCN3C(=O)OC(C)(C)C)ccc21 -US04183868,1,COCCO.Cc1cccc(C)c1N>>COCCNc1c(C)cccc1C -US20130296312A1,1,COc1ccc(N)cn1.COc1ccccc1CNc1cccn2nc(Cl)nc12>>COc1ccc(Nc2nc3c(NCc4ccccc4OC)cccn3n2)cn1 -US20090264650A1,2,CO.O=C(O)C1CCN(C2CCCCC2)C1=O>>COC(=O)C1CCN(C2CCCCC2)C1=O -US20120094979A1,6,CC(C)Oc1ccc(-c2cnc(-c3ccc4c(c3)CCN(C(=O)OC(C)(C)C)CC4)s2)cc1Cl>>CC(C)Oc1ccc(-c2cnc(-c3ccc4c(c3)CCNCC4)s2)cc1Cl -US20140234965A1,7,COC(=O)c1cccc(Nc2nc(Oc3ccccc3)nc(Oc3ccc(C(C)(C)C)cc3)n2)c1>>CC(C)(C)c1ccc(Oc2nc(Nc3cccc(CO)c3)nc(Oc3ccccc3)n2)cc1 -US07608717B2,2,CN(C)CCn1c(=O)[nH]c2cccnc21.O=S(=O)(Cl)c1cccc(F)c1>>CN(C)CCn1c(=O)n(S(=O)(=O)c2cccc(F)c2)c2cccnc21 -US20110269810A1,6,O=C1c2ccccc2C(=O)N1CCCCCCNc1ccccc1>>NCCCCCCNc1ccccc1 -US08063099B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c1.N#Cc1ccc(C(=O)O)cc1>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2ccc(C#N)cc2)c1 -US07666848B2,7,COc1ccc(C=Cc2sccc2OC2OC(CO)C(O)C(O)C2O)cc1>>COc1ccc(CCc2sccc2OC2OC(CO)C(O)C(O)C2O)cc1 -US20090270394A1,2,CC(C)(C)c1cc(C(=O)NC2(C(=O)O)CC2)cc(C(C)(C)C)c1O.NCc1nccs1>>CC(C)(C)c1cc(C(=O)NC2(C(=O)NCc3nccs3)CC2)cc(C(C)(C)C)c1O -US20140303156A1,2,Fc1ccc2c(c1)CCN2.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2cc(F)ccc21 -US03948947,2,CNC1c2ccccc2Oc2ccccc21.O=C(Cl)Cl>>CN(C(=O)Cl)C1c2ccccc2Oc2ccccc21 -US20030207880A1,1,C1COCCN1.O=Cc1cc(Br)c(Cl)s1>>Clc1sc(CN2CCOCC2)cc1Br -US20120319052A1,3,CC1(C)c2ccccc2N2c3ccccc3Sc3cc(Br)cc1c32.OB(O)c1ccc2c(c1)c1ccccc1n2-c1ccccc1>>CC1(C)c2ccccc2N2c3ccccc3Sc3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc1c32 -US20100113782A1,1,CC(C)(C)c1cccc(NC(=O)c2ccc(C3CCNCC3)cc2)c1.Cc1cc(Br)ccc1C(=O)O>>Cc1cc(N2CCC(c3ccc(C(=O)Nc4cccc(C(C)(C)C)c4)cc3)CC2)ccc1C(=O)O -US20100298385A1,1,CNC(=O)c1cc(Cl)ccn1.Nc1ccc(O)cc1>>CNC(=O)c1cc(Oc2ccc(N)cc2)ccn1 -US20100120775A1,1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.COC(=O)c1cc(C(=O)OC)c2ccc(-c3ccc(O)cc3)cc2n1>>COC(=O)c1cc(C(=O)OC)c2ccc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)cc2n1 -US04139621,2,CC(=O)OC(C)=O.Clc1cc(N2CCNCC2)cc(Cl)c1Cl>>CC(=O)N1CCN(c2cc(Cl)c(Cl)c(Cl)c2)CC1 -US20130158075A1,6,COC(=O)C1CCC(c2ncc(-c3ccc(NC(=O)Nc4c(F)cccc4F)cc3)s2)CC1>>O=C(Nc1ccc(-c2cnc(C3CCC(C(=O)O)CC3)s2)cc1)Nc1c(F)cccc1F -US20100130737A1,6,CCOC(=O)C1(NC(=O)Cc2ccc(OC3Cc4ccccc4C3)cc2)Cc2ccc(-c3ccc(Cl)cc3)cc2C1>>O=C(Cc1ccc(OC2Cc3ccccc3C2)cc1)NC1(C(=O)O)Cc2ccc(-c3ccc(Cl)cc3)cc2C1 -US20040006141A1,9,CCCCC(Cc1ccc(OCCCN=[N+]=[N-])cc1)C(=O)OCC>>CCCCC(Cc1ccc(OCCCN)cc1)C(=O)OCC -US20010006969A1,2,C=CCNc1nc(N)c2cc([N+](=O)[O-])ccc2n1.CC(C)(C)N=C=O>>C=CCNc1nc(NC(=O)NC(C)(C)C)c2cc([N+](=O)[O-])ccc2n1 -US20100298287A1,9,CCC(CC)c1ccc(Cl)c2nc3n(c12)CCN3c1ccc(Cl)cc1Br.N#C[Cu]>>CCC(CC)c1ccc(Cl)c2nc3n(c12)CCN3c1ccc(Cl)cc1C#N -US20150152108A1,6,COC(=O)CNC(=O)c1ccc2c(n1)N(C(=O)Nc1ccccn1)[C@H]1CCN2C1>>O=C(O)CNC(=O)c1ccc2c(n1)N(C(=O)Nc1ccccn1)[C@H]1CCN2C1 -US20100056593A1,6,CCOC(=O)CNC(=O)CSc1ncc(Br)n1-c1ccc(C#N)c2ccccc12>>N#Cc1ccc(-n2c(Br)cnc2SCC(=O)NCC(=O)O)c2ccccc12 -US20120289505A1,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(F)cc4C(F)(F)F)cc3)cc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(F)cc4C(F)(F)F)cc3)cc2C1=O -US20090258817A1,1,COc1ccccc1S.O=C(O)c1ccc(CBr)cc1>>COc1ccccc1SCc1ccc(C(=O)O)cc1 -US20090221555A1,1,CC(CNS(C)(=O)=O)Nc1nc(Cl)ncc1Cl.COCCN1CCc2ccc(N)cc2CC1>>COCCN1CCc2ccc(Nc3ncc(Cl)c(NC(C)CNS(C)(=O)=O)n3)cc2CC1 -US20120059162A1,7,NC(=O)c1onc(-c2ccc(Br)cc2)c1[N+](=O)[O-]>>NC(=O)c1onc(-c2ccc(Br)cc2)c1N -US06107329,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.OC1CCNCC1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC(O)CC1 -US05561141,1,COc1cc2c(cc1OC)CNCC2.COc1ccc(C(C#N)(CCCCl)Sc2ccc(C)cc2)cc1OC>>COc1ccc(C(C#N)(CCCN2CCc3cc(OC)c(OC)cc3C2)Sc2ccc(C)cc2)cc1OC -US06852721B2,6,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1cncc(-c2ccsc2)c1>>c1cc(-c2cncc(N3C[C@@H]4C[C@H]3CN4)c2)cs1 -US20020052322A1,2,COC(=O)[C@@H](N)Cc1ccc(O)cc1.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1 -US20100197682A1,6,Cn1nnnc1CCNC(=O)OC(C)(C)C>>Cn1nnnc1CCN -US08039493B2,1,BrCC1CC1.CS(=O)(=O)c1cccc(-c2ccc(CNS(=O)(=O)c3ccccc3C(F)(F)F)s2)c1>>CS(=O)(=O)c1cccc(-c2ccc(CN(CC3CC3)S(=O)(=O)c3ccccc3C(F)(F)F)s2)c1 -US06492399B1,1,Brc1cncc(Br)c1.CCS>>CCSc1cncc(Br)c1 -US20060089392A1,2,CO.O=C(O)c1ccc(O)c(C(F)(F)F)c1>>COC(=O)c1ccc(O)c(C(F)(F)F)c1 -US04940710,1,CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21.Clc1ccc(C2CNCCN2)s1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(c4ccc(Cl)s4)C3)cc21 -US20060154929A1,1,CC(=O)c1c(C(C)=O)c(C)n(-c2ccc(O)c(Cl)c2)c1C.CCBr>>CCOc1ccc(-n2c(C)c(C(C)=O)c(C(C)=O)c2C)cc1Cl -US08962621B2,6,CN(CCC(c1c[nH]c2ccccc12)N1CCOCC1)Cc1ccccc1>>CNCCC(c1c[nH]c2ccccc12)N1CCOCC1 -US20050288270A1,1,CCC=O.Clc1ccc(C2CNC2)cn1>>CCCN1CC(c2ccc(Cl)nc2)C1 -US20090312382A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1cccc([C@@H]2CNCC[C@H]2c2ccccc2)c1>>CC(C)(C)OC(=O)N1CC[C@@H](c2ccccc2)[C@H](c2cccc(Cl)c2)C1 -US07767691B2,1,BrCCCOc1ccccc1.N#CC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2>>N#CC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCOc3ccccc3)(CC1)C2 -US20130035326A1,6,CC(C)(C)OC(=O)Nc1ccc(-c2cnc(CCCOC3CCCCO3)nc2)cc1>>CC(C)(C)OC(=O)Nc1ccc(-c2cnc(CCCO)nc2)cc1 -US06358980B1,6,CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1>>CC#CCOc1ccc(S(=O)(=O)C2(C(=O)O)CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1 -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CNC[C@H]1c1ccc(Cl)c(Cl)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C1CCOCC1>>CN(C(=O)N(C)[C@@H]1CN(C(=O)C2CCOCC2)C[C@H]1c1ccc(Cl)c(Cl)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090047379A1,2,CC(N)C(C)(C)C.Cc1cc(C)c(C(=O)O)c(C)c1>>Cc1cc(C)c(C(=O)NC(C)C(C)(C)C)c(C)c1 -US20150203442A1,2,Nc1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O.O=C(Cl)CCl>>O=C(CCl)Nc1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O -US20060211603A1,1,C[C@H]1NC(=O)O[C@H]1c1ccccc1.O=C(CBr)OCc1ccccc1>>C[C@@H]1[C@H](c2ccccc2)OC(=O)N1CC(=O)OCc1ccccc1 -US20150191502A1,6,COc1ccc(Cc2cc(I)ccc2Cl)cc1>>Oc1ccc(Cc2cc(I)ccc2Cl)cc1 -US20140275185A1,9,COC(=O)c1ccc(CBr)c(F)c1.[C-]#N>>COC(=O)c1ccc(CC#N)c(F)c1 -US20090215759A1,1,COc1cc(N)ccc1-n1cnc(C)c1.Clc1cccc(Cc2ccnc(Cl)n2)c1>>COc1cc(Nc2nccc(Cc3cccc(Cl)c3)n2)ccc1-n1cnc(C)c1 -US20110190269A1,1,COc1cc(Br)ccc1-n1cnc(C)c1.Cc1cc(-c2ccc(F)cc2C)c2nc(N)nn2c1>>COc1cc(Nc2nc3c(-c4ccc(F)cc4C)cc(C)cn3n2)ccc1-n1cnc(C)c1 -US20050192310A1,7,O=C(O)c1ccncc1I>>OCc1ccncc1I -US20150065343A1,6,CCOC(=O)c1sc(/C=C/C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)cc1C>>Cc1cc(/C=C/C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)sc1C(=O)O -US20130331378A1,9,COC(=O)c1cccc(C(O)c2c(CC(C)C)nn3cc(OC)ccc23)n1>>COC(=O)c1cccc(Cc2c(CC(C)C)nn3cc(OC)ccc23)n1 -US08546402B2,3,COc1ccc(OC)c(OC)c1.O=C(Cl)CCCCCBr>>COc1cc(OC)c(C(=O)CCCCCBr)cc1OC -US20100234344A1,9,Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3CCl)c2n1.N>>Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3CN)c2n1 -US05215994,1,CCCC(=O)Nc1nc(C)cc(C)c1[N+](=O)[O-].Cc1ccc(C#N)n1-c1ccc(COS(C)(=O)=O)cc1>>CCCC(=O)N(Cc1ccc(-n2c(C)ccc2C#N)cc1)c1nc(C)cc(C)c1[N+](=O)[O-] -US20070032485A1,7,CCOC(=O)N1c2ccc(C#N)nc2[C@@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)N1c2ccc(CN)nc2[C@@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC -US20090227560A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn([C@H]3CCCCC3(O)CCO)c2-c2ccccc2)[C@H](Cc2ccccc2)C1.CI>>COCCC1(O)CCCC[C@@H]1n1cnc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2Cc2ccccc2)c1-c1ccccc1 -US20090298824A1,6,COC(=O)c1cc(C#N)cc2nc(Nc3cccc(Cl)c3Cl)[nH]c12>>N#Cc1cc(C(=O)O)c2[nH]c(Nc3cccc(Cl)c3Cl)nc2c1 -US05438052,1,NO.O=C(Cl)c1ccc(CCl)cc1>>O=C(NO)c1ccc(CCl)cc1 -US20030036652A1,7,O=[N+]([O-])c1ccc(N2CCCC2)nc1>>Nc1ccc(N2CCCC2)nc1 -US05652233,6,COC(=O)c1cc(OC)cc([N+](=O)[O-])c1>>COc1cc(C(=O)O)cc([N+](=O)[O-])c1 -US06248755B1,3,O=C1CCN(Cc2ccccc2)CC1.c1ccc(CCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>C(CCc1ccccc1)=C1CCN(Cc2ccccc2)CC1 -US08168635B2,1,CCNCC.COc1ccc(F)cc1CC[C@H]1CC[C@H](CBr)O1>>CCN(CC)C[C@H]1CC[C@H](CCc2cc(F)ccc2OC)O1 -US20150274705A1,6,Cc1cnc(Nc2ccc3c(C)n(C)nc3c2)nc1NC1CCC2(CC1)CCN(C(=O)OC(C)(C)C)CC2>>Cc1cnc(Nc2ccc3c(C)n(C)nc3c2)nc1NC1CCC2(CCNCC2)CC1 -US08324221B2,7,O=C1Nc2cccc(Br)c2C12CCN(Cc1ccccc1)CC2>>Brc1cccc2c1C1(CCN(Cc3ccccc3)CC1)CN2 -US20150232465A1,1,CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)cc2NC[C@@H]1C.Clc1nc2ccccc2o1>>CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)cc2N(c2nc3ccccc3o2)C[C@@H]1C -US20100210466A1,3,Cc1ccc(B(O)O)cc1C1C(=O)C(C)(C)OC(C)(C)C1=O.Clc1cnc(Br)c(Cl)c1>>Cc1ccc(-c2ncc(Cl)cc2Cl)cc1C1C(=O)C(C)(C)OC(C)(C)C1=O -US20110152316A1,7,COC/C=C/c1ccc(C)c(CN(C(=O)OC(C)(C)C)C2CC2)c1>>COCCCc1ccc(C)c(CN(C(=O)OC(C)(C)C)C2CC2)c1 -US08088767B2,7,Cc1cc([N+](=O)[O-])c(Cl)cc1OCCCN1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc(N)c(Cl)cc1OCCCN1CCN(C(=O)OC(C)(C)C)CC1 -US07279478B2,7,O=C(c1ccccc1)c1ccc(Br)cc1>>OC(c1ccccc1)c1ccc(Br)cc1 -US20110077279A1,2,CC(Cl)OC(=O)Cl.O=C(CCCC(CO[N+](=O)[O-])O[N+](=O)[O-])O[C@@H]1CO[C@@H]2[C@H](O)CO[C@H]12>>CC(Cl)OC(=O)O[C@@H]1CO[C@@H]2[C@H](OC(=O)CCCC(CO[N+](=O)[O-])O[N+](=O)[O-])CO[C@H]12 -US20130090340A1,3,C=O.COC(=O)c1cn(CCN)c(Cl)c1-c1cccc(C#N)c1>>COC(=O)c1c(-c2cccc(C#N)c2)c(Cl)n2c1CNCC2 -US07781426B2,7,CCOC(=O)C[C@@H]1CC[C@@H](C(=O)O)CC1>>CCOC(=O)C[C@@H]1CC[C@@H](CO)CC1 -US20040092737A1,6,COc1cc(C2(O)CCN(Cc3ccccc3)CC2)ccc1C(OC)OC>>COc1cc(C2(O)CCN(Cc3ccccc3)CC2)ccc1C=O -US08030354B2,7,COC(=O)c1ccc(-c2cc(OC)ccc2F)c(C2CCCCCC2)c1>>COc1ccc(F)c(-c2ccc(CO)cc2C2CCCCCC2)c1 -US20100197681A1,1,NC1CCCCC1.Nc1nc2cccc(Cl)n2n1>>Nc1nc2cccc(NC3CCCCC3)n2n1 -US20070249670A1,6,COC(=O)c1sc(-c2ccc(OC)cc2)cc1N>>COc1ccc(-c2cc(N)c(C(=O)O)s2)cc1 -US20030092694A1,1,CCN1CCNCC1.Clc1ccc(OCCOc2nccnc2Cl)cc1>>CCN1CCN(c2nccnc2OCCOc2ccc(Cl)cc2)CC1 -US05294609,2,CN.O=C([O-])c1ccc2c(c1)OC(c1ccccc1)(c1ccccc1)O2>>CNC(=O)c1ccc2c(c1)OC(c1ccccc1)(c1ccccc1)O2 -US04160828,1,CP(C)(=O)COC(=O)c1ccccc1N.FC(F)(F)c1cccc2c(Cl)ccnc12>>CP(C)(=O)COC(=O)c1ccccc1Nc1ccnc2c(C(F)(F)F)cccc12 -US20090176841A1,2,Cc1ccc(N)c2ccn(Cc3ccc(O[Si](C(C)C)(C(C)C)C(C)C)c(C(C)C)c3)c12.O=C(O)Cc1nnn[nH]1>>Cc1ccc(NC(=O)Cc2nnn[nH]2)c2ccn(Cc3ccc(O[Si](C(C)C)(C(C)C)C(C)C)c(C(C)C)c3)c12 -US05811433,6,CCOC(=O)c1cn(-c2ccc(F)cc2F)c2c(F)c(Cl)ncc2c1=O>>O=C(O)c1cn(-c2ccc(F)cc2F)c2c(F)c(Cl)ncc2c1=O -US20040192685A1,7,COc1ccc2c(c1)CCN=C2C1CCCCC1>>COc1ccc2c(c1)CCNC2C1CCCCC1 -US20070185092A1,7,COC(=O)c1cn(C)c(-c2ccc(I)cc2)n1>>Cn1cc(CO)nc1-c1ccc(I)cc1 -US20150238558A1,2,COC[C@@H](NCc1ccc2[nH]ccc2c1)c1ccccc1.O=C(O)[C@@H]1Cc2ccccc2CN1C(=O)OCc1ccccc1>>COC[C@H](c1ccccc1)N(Cc1ccc2[nH]ccc2c1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)OCc1ccccc1 -US05623049,1,CC(C)(C)OC(=O)CBr.NCCO>>CC(C)(C)OC(=O)CNCCO -US20090192162A1,1,CCOC(=O)COc1ccc(Sc2cc(O)cc(C#Cc3ccc(Cl)cc3)c2)cc1Cl.OCCCN1CCCCC1>>CCOC(=O)COc1ccc(Sc2cc(C#Cc3ccc(Cl)cc3)cc(OCCCN3CCCCC3)c2)cc1Cl -US04761415,7,N#Cc1cc(F)cc(F)c1>>NCc1cc(F)cc(F)c1 -US20050010031A1,6,CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(Cc2ccc(F)cc2)NC(=O)OC(C)(C)C)C(COC)C1>>CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(N)Cc2ccc(F)cc2)C(COC)C1 -US04565817,1,CC(=O)CCc1nc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)no1.CC(C)N>>CC(C)NC(C)CCc1nc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)no1 -US20150111870A1,8,COc1nc2ccc(C(O)c3ccc(C)nc3C)cc2c(Cl)c1CC(C)C>>COc1nc2ccc(C(=O)c3ccc(C)nc3C)cc2c(Cl)c1CC(C)C -US05990156,6,COC(=O)C1=C[C@@H](O)[C@@H](NC(C)=O)[C@H](C(=O)NCCCCCc2ccccc2)O1>>CC(=O)N[C@@H]1[C@H](O)C=C(C(=O)O)O[C@H]1C(=O)NCCCCCc1ccccc1 -US09006449B2,3,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(Br)nc1.OB(O)c1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(-c2cccc(C(F)(F)F)c2)nc1 -US20070213305A1,1,CNc1ccc(OC)cc1.Clc1ncnc2ccsc12>>COc1ccc(N(C)c2ncnc3ccsc23)cc1 -US20050203087A1,2,CC(C)N=C=O.CCOC(=O)COc1c(C(=O)OC)sc(-c2ccc(CN)cc2)c1Br>>CCOC(=O)COc1c(C(=O)OC)sc(-c2ccc(CNC(=O)NC(C)C)cc2)c1Br -US20120316161A1,6,CCCC(C(=O)OCC)c1c(C)nc2ccnn2c1N1CC[C@@H](NS(=O)(=O)c2ccc(Cl)cc2)C1>>CCCC(C(=O)O)c1c(C)nc2ccnn2c1N1CC[C@@H](NS(=O)(=O)c2ccc(Cl)cc2)C1 -US04377695,1,COC(=O)CCCCCCCBr.O=c1[nH]c2cc([N+](=O)[O-])ccc2o1>>COC(=O)CCCCCCCn1c(=O)oc2ccc([N+](=O)[O-])cc21 -US20140275071A1,1,ClCCOCCOC1CCCCO1.Cn1c(=O)[nH]c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2COCC[Si](C)(C)C>>Cn1c(=O)n(CCOCCOC2CCCCO2)c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2COCC[Si](C)(C)C -US05455273,1,CN.CNCc1c(C(=O)OC(C)(C)C)cccc1C1CCC(=O)CC1>>CNCc1c(C(=O)OC(C)(C)C)cccc1[C@@H]1CC[C@@H](NC)CC1 -US06211227B1,2,C[C@](O)(C(=O)O)C(F)(F)F.Nc1cccc2c1C(=O)c1sccc1CS2>>C[C@](O)(C(=O)Nc1cccc2c1C(=O)c1sccc1CS2)C(F)(F)F -US07495007B2,1,CC(C)I.O=Cc1cc(Cl)ccc1O>>CC(C)Oc1ccc(Cl)cc1C=O -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccccc3)cc2n(CC2CC2)c1=O.COCCN>>COCCNC(=O)c1c(O)c2ncc(Cc3ccccc3)cc2n(CC2CC2)c1=O -US20080300270A1,7,CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(O)c([N+](=O)[O-])c1>>CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(N)c(O)c(Br)c1 -US06258854B1,1,CC(=O)[O-].COc1ccc(C(=O)CBr)cc1>>COc1ccc(C(=O)COC(C)=O)cc1 -US06291481B1,1,N#CCCl.Nc1c(Cl)cc(C(=O)OCC2CCNCC2)c2c1OCCO2>>N#CCN1CCC(COC(=O)c2cc(Cl)c(N)c3c2OCCO3)CC1 -US08026247B2,1,CCn1cc(C(=O)O)c2ccc(O)cc21.Clc1cc(Cl)ncn1>>CCn1cc(C(=O)O)c2ccc(Oc3cc(Cl)ncn3)cc21 -US20140349989A1,1,Clc1ccnc(Cl)n1.O=C(NCCCCCCc1c[nH]c2ccccc12)NCc1cccnc1>>O=C(NCCCCCCc1cn(-c2nccc(Cl)n2)c2ccccc12)NCc1cccnc1 -US20080234327A1,3,N#Cc1ccc(B(O)O)cc1.O=C1CCc2cc(Br)ccc2C1>>N#Cc1ccc(-c2ccc3c(c2)CCC(=O)C3)cc1 -US06277877B1,2,C1CSCN1.CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCSC1 -US20110275797A1,1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(CCBr)ccc1OCc1ccccc1.CN1CCNCC1>>CN1CCN(CCc2ccc(OCc3ccccc3)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)OC(C)(C)C)c2)CC1 -US20150191465A1,1,C[C@H](N)c1nc2ccn(C)c2cc1N(C)C1CN(C(=O)OC(C)(C)C)C1.Cc1nc(N)nc(Cl)c1C#N>>Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N(C)C2CN(C(=O)OC(C)(C)C)C2)c1C#N -US20140128385A1,6,Cc1cc(C#N)cnc1C(=O)Nc1cc(F)c(F)c([C@]2(C(F)F)COCC(NC(=O)OC(C)(C)C)=N2)c1>>Cc1cc(C#N)cnc1C(=O)Nc1cc(F)c(F)c([C@]2(C(F)F)COCC(N)=N2)c1 -US20100216766A1,7,CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)C1>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc3nccc(Oc4ccc(N)cc4F)c3s2)C1 -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)cc3Cl)c2cc1OC.Cc1cc(C)cc(C(=O)N=C=S)c1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4cc(C)cc(C)c4)cc3Cl)c2cc1OC -US06809110B2,6,CCO[C@@H](Cc1ccc(OCc2csc(-c3ccc(Cl)cc3)n2)cc1F)C(=O)OC>>CCO[C@@H](Cc1ccc(OCc2csc(-c3ccc(Cl)cc3)n2)cc1F)C(=O)O -US07652015B2,6,CC(C)(C)OC(=O)N1CCC(Oc2cc([N+](=O)[O-])ccn2)CC1>>O=[N+]([O-])c1ccnc(OC2CCNCC2)c1 -US06579872B1,2,CCOCCOc1ccc(C(=O)Nc2cc(N)ccc2C)cc1.O=C(Cl)c1ccc2ccccc2c1>>CCOCCOc1ccc(C(=O)Nc2cc(NC(=O)c3ccc4ccccc4c3)ccc2C)cc1 -US20130281438A1,7,O=[N+]([O-])c1ccccc1S(=O)(=O)NC1CCC1>>Nc1ccccc1S(=O)(=O)NC1CCC1 -US05475106,1,CC(C)(C)OC(=O)CBr.CCOC(=O)c1ccccc1NC(=O)CN1C(=O)c2ccccc2C1=O>>CCOC(=O)c1ccccc1N(CC(=O)OC(C)(C)C)C(=O)CN1C(=O)c2ccccc2C1=O -US06121448,3,Brc1cnc(I)nc1.CCCCCCCCOc1ccc(B(O)O)c(F)c1F>>CCCCCCCCOc1ccc(-c2ncc(Br)cn2)c(F)c1F -US20070066624A1,2,CN.O=C(O)c1ccc(Oc2ccc(CN3CCC(N4C(=O)N(c5cccnc5)CC4c4cccc(Cl)c4)CC3)cn2)cc1>>CNC(=O)c1ccc(Oc2ccc(CN3CCC(N4C(=O)N(c5cccnc5)CC4c4cccc(Cl)c4)CC3)cn2)cc1 -US20050101595A1,2,CN1CCNCC1.O=S(=O)(O)Cl>>CN1CCN(S(=O)(=O)O)CC1 -US07001897B2,6,CC(C)(C)C(O[SiH](c1ccccc1)c1ccccc1)C(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)(C)C(O[SiH](c1ccccc1)c1ccccc1)C(N)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C -US20080269209A1,9,Fc1ccc(-n2ncc3cc(Br)c4cnccc4c32)cc1.N#C[Cu]>>N#Cc1cc2cnn(-c3ccc(F)cc3)c2c2ccncc12 -US04246263,1,ClCCc1ccncc1.OCCS>>OCCSCCc1ccncc1 -US03952001,1,CC(C)S(=O)c1nc[nH]n1.CCCN(CCC)C(=O)Cl>>CCCN(CCC)C(=O)n1cnc(S(=O)C(C)C)n1 -US20100004238A1,1,C=O.O=C(NCCn1ccc2ncnc(Nc3ccc(Oc4ccc5ccsc5c4)c(Cl)c3)c21)C1CCNCC1>>CN1CCC(C(=O)NCCn2ccc3ncnc(Nc4ccc(Oc5ccc6ccsc6c5)c(Cl)c4)c32)CC1 -US20070249637A1,2,C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O.C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2nc(-c3ccccn3)nc3ccsc23)CN1)C(=O)OC>>C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](Oc2nc(-c3ccccn3)nc3ccsc23)C[C@H]1C(=O)N[C@]1(C(=O)OC)C[C@H]1C=C -US08227500B2,7,CCOC(=O)c1cn(COCc2ccccc2)nc1OCc1ccccc1>>OCc1cn(COCc2ccccc2)nc1OCc1ccccc1 -US20090048258A1,3,CC1(C)OB(c2ccc(CN3CCOCC3)cc2)OC1(C)C.O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(Cl)cc(-c2ccccc2)n1>>O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(-c2ccc(CN3CCOCC3)cc2)cc(-c2ccccc2)n1 -US20080124571A1,3,Brc1cccc(I)c1.OB(O)c1ccc2ccc3cccc4ccc1c2c34>>Brc1cccc(-c2ccc3ccc4cccc5ccc2c3c45)c1 -US20090286790A1,1,CCC1CC(=O)CCN1C(=O)OC(C)(C)C.Nc1ccc(Br)cc1>>CCC1CC(Nc2ccc(Br)cc2)CCN1C(=O)OC(C)(C)C -US04010177,1,CNCC1CC1.ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>CN(Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2)CC1CC1 -US20120208827A1,6,CC(C)(C)OC(=O)N1CC[C@@H](CNc2ccccc2[N+](=O)[O-])C1>>O=[N+]([O-])c1ccccc1NC[C@@H]1CCNC1 -US04680402,1,CC1CCCNC1.O=C(c1ccc(Cl)cc1)c1cc([N+](=O)[O-])ccc1Cl>>CC1CCCN(c2ccc([N+](=O)[O-])cc2C(=O)c2ccc(Cl)cc2)C1 -US08293768B2,2,Cc1cc(N2CCN(Cc3ccc(C(F)(F)F)cc3)C2=O)sc1C(=O)O.NCc1cccnc1>>Cc1cc(N2CCN(Cc3ccc(C(F)(F)F)cc3)C2=O)sc1C(=O)NCc1cccnc1 -US08487112B2,1,ClCc1cnc(Cl)s1.O=C1C=C(NCc2ccccc2)CO1>>O=C1C=C(N(Cc2ccccc2)Cc2cnc(Cl)s2)CO1 -US20090247567A1,2,CC(=O)OC(C)=O.Nc1ccc(-c2cc3c(s2)-c2ncccc2OCC3)cn1>>CC(=O)Nc1ccc(-c2cc3c(s2)-c2ncccc2OCC3)cn1 -US20140249134A1,7,COc1ccc(Cc2ncnn2-c2cc(C#Cc3ccc(C)cn3)nc(C)n2)cc1OC>>COc1ccc(Cc2ncnn2-c2cc(CCc3ccc(C)cn3)nc(C)n2)cc1OC -US07271197B2,2,CS(=O)(=O)Cl.N#Cc1cccc(COCCO)c1>>CS(=O)(=O)OCCOCc1cccc(C#N)c1 -US05084085,1,COC(=O)C(C)Br.Cc1nn(-c2cc(Oc3ccc(O)cc3Cl)c(Cl)cc2Cl)c(=O)n1C(F)F>>COC(=O)C(C)Oc1ccc(Oc2cc(-n3nc(C)n(C(F)F)c3=O)c(Cl)cc2Cl)c(Cl)c1 -US20060287311A1,2,Nc1ccc2c(c1)Cc1c-2[nH]c(=O)c2ccccc12.O=S(=O)(Cl)CCCCl>>O=c1[nH]c2c(c3ccccc13)Cc1cc(NS(=O)(=O)CCCCl)ccc1-2 -US07105544B2,2,Cc1ccc(NC(=O)C(C)C)cc1C1CCN(CCCN)CC1.O=C(O)C1(c2ccc(Cl)cc2)CCCCC1>>Cc1ccc(NC(=O)C(C)C)cc1C1CCN(CCCNC(=O)C2(c3ccc(Cl)cc3)CCCCC2)CC1 -US20050090529A1,6,COc1ccc(Cn2nc(-c3ncc[nH]3)c3cc(-c4cncc(CNC(C)C)c4C)ccc32)cc1>>Cc1c(CNC(C)C)cncc1-c1ccc2[nH]nc(-c3ncc[nH]3)c2c1 -US20040152741A1,2,CC(C)(C)OC(=O)NC(C(=O)O)c1ccccc1.Nc1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)NC(C(=O)Nc1ccc(C(F)(F)F)cc1)c1ccccc1 -US20090156678A1,7,C[C@H](N=Cc1ccc(OCc2cccc(F)c2)cc1)C(N)=O>>C[C@H](NCc1ccc(OCc2cccc(F)c2)cc1)C(N)=O -US04981992,7,CCOC(=O)C(CNC(C)=O)C(C)=O>>CCOC(=O)[C@@H](CNC(C)=O)[C@@H](C)O -US06329400B1,6,CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cccnc1)C(C)(C)C>>CC(C)(C)[C@H](N)C(=O)Nc1cccnc1 -US06960578B2,3,CC(C)(C)OC(=O)Nc1ccc(I)cc1[N+](=O)[O-].OB(O)c1ccc(F)cc1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2)cc1[N+](=O)[O-] -US07737166B2,1,CCN[C@H]1CCNC1.Cc1c(-c2ccccc2)c(F)c2oc(C3CC3)nc2c1C#N>>CCN[C@H]1CCN(c2c(-c3ccccc3)c(C)c(C#N)c3nc(C4CC4)oc23)C1 -US07495007B2,3,C#C[Si](C)(C)C.COc1cc(I)cc(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1OCCO>>C#Cc1cc(OC)c(OCCO)c(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1 -US20110275797A1,6,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(-c2ccccn2)cc1O>>O=C(Nc1cc(-c2ccccc2)ccc1C(=O)O)c1ccc(-c2ccccn2)cc1O -US05807851,2,CC1Cc2ccc(Cl)cc2C(c2ccc([N+](=O)[O-])cc2)=NN1.CCC(=O)OC(=O)CC>>CCC(=O)N1N=C(c2ccc([N+](=O)[O-])cc2)c2cc(Cl)ccc2CC1C -US06455286B1,6,CC(=O)Oc1ccc2c(C)c(CN3C(=O)c4ccccc4C3=O)c(=O)oc2c1C>>Cc1c(CN2C(=O)c3ccccc3C2=O)c(=O)oc2c(C)c(O)ccc12 -US08273769B2,1,Cc1ccc(F)cc1[N+](=O)[O-].Sc1ccccc1>>Cc1ccc(Sc2ccccc2)cc1[N+](=O)[O-] -US20090221555A1,7,COc1cc2c(cc1[N+](=O)[O-])CCN(CCNC(C)=O)CC2>>COc1cc2c(cc1N)CCN(CCNC(C)=O)CC2 -US07279470B2,2,NCC1CCNCC1.O=C(Cl)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1>>NCC1CCN(C(=O)Oc2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)CC1 -US20030207913A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(CC(C)=O)OCC>>CC(=O)C=C1CCN(C(=O)OC(C)(C)C)CC1 -US06670386B2,2,CC(C)(C)OC(=O)N1CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)O.N#Cc1ccc(N)c2ccccc12>>CC(C)(C)OC(=O)N1CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)Nc1ccc(C#N)c2ccccc12 -US06492403B1,1,CCCCc1ccc(B(O)O)cc1.COC(=S)c1cc(N)c(C)s1>>CCCCc1ccc(Nc2cc(C(=S)OC)sc2C)cc1 -US20060194969A1,1,CI.Cc1nc2c([N+](=O)[O-])cc(S(=O)(=O)N(C)C)cc2[nH]1>>Cc1nc2c([N+](=O)[O-])cc(S(=O)(=O)N(C)C)cc2n1C -US07902400B2,2,CC1CCCC1N.O=C(Cl)c1ccc(F)c(F)c1>>CC1CCCC1NC(=O)c1ccc(F)c(F)c1 -US20080214615A1,2,CCN(CC)C(=O)c1cccc(CN(C)C(=O)OC(C)(C)C)c1CO.CS(=O)(=O)Cl>>CCN(CC)C(=O)c1cccc(CN(C)C(=O)OC(C)(C)C)c1COS(C)(=O)=O -US20080125409A1,2,CCOC(=O)C(N)C(=O)OCC.O=C(O)c1cnccn1>>CCOC(=O)C(NC(=O)c1cnccn1)C(=O)OCC -US08063099B2,2,CC(=O)OC(C)=O.COC(=O)c1nc(C)sc1-c1cccc(N)c1>>COC(=O)c1nc(C)sc1-c1cccc(NC(C)=O)c1 -US05030654,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)C(CCCCN)CC1(C(=O)N[C@H]2CC[C@@H](C(=O)O)CC2)CCCC1>>CC(=O)NCCCCC(CC1(C(=O)N[C@H]2CC[C@@H](C(=O)O)CC2)CCCC1)C(=O)OC(C)(C)C -US20100286117A1,6,CCCCc1noc(C)c1CN1C(=O)c2ccccc2C1=O>>CCCCc1noc(C)c1CN -US05714488,6,CCOC(=O)C(=NO)C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1>>O=C(O)C(=NO)C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 -US06433174B1,2,CCOC(=O)Cl.NCC(CC(=O)O)c1ccc(Cl)c(Cl)c1>>CCOC(=O)NCC(CC(=O)O)c1ccc(Cl)c(Cl)c1 -US07935699B2,2,CC(C)(O)Cn1ccc(N)n1.O=C(O)C(CC1CCCC1)c1ccc2c(c1)CCS2(=O)=O>>CC(C)(O)Cn1ccc(NC(=O)C(CC2CCCC2)c2ccc3c(c2)CCS3(=O)=O)n1 -US20150282482A1,2,COC(=O)c1cc2cc(N)ccc2s1.O=C(Cl)CCl>>COC(=O)c1cc2cc(NC(=O)CCl)ccc2s1 -US05066648,2,CCCCCCCCCCO.O=C1CC[C@@H](C(=O)O)N1>>CCCCCCCCCCOC(=O)[C@@H]1CCC(=O)N1 -US04952571,3,C1COCCN1.COc1cc2cc(C=O)sc2cc1OC.[C-]#N>>COc1cc2cc(C(C#N)N3CCOCC3)sc2cc1OC -US20150080549A1,6,CC(C)(C)SSC[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>CC(C)(C)SSC[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O -US08754053B2,1,N#Cc1cc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1F.c1nc[nH]n1>>N#Cc1cc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1-n1cncn1 -US08338605B2,1,Cc1ccc(O)c(N)c1.Cc1ccc2c(Cl)ccnc2n1>>Cc1ccc(O)c(Nc2ccnc3nc(C)ccc23)c1 -US20100197749A1,2,N[C@H](Cc1ccccc1)C(=O)O.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc(Cl)cc1 -US20090192147A1,1,CCOC(=O)CBr.CCOC(=O)c1cc2cc(OC)ccc2[nH]1>>CCOC(=O)Cn1c(C(=O)OCC)cc2cc(OC)ccc21 -US05650428,1,CCOC(=O)Cc1ccc(NC(=O)C(COS(C)(=O)=O)NS(=O)(=O)c2ccc(F)cc2)cc1.c1c[nH]cn1>>CCOC(=O)Cc1ccc(NC(=O)C(Cn2ccnc2)NS(=O)(=O)c2ccc(F)cc2)cc1 -US06310070B1,6,COc1cccc(-c2nc3ncn(Cc4ccccc4)c3c(=O)[nH]2)c1>>O=c1[nH]c(-c2cccc(O)c2)nc2ncn(Cc3ccccc3)c12 -US06093838,9,Cc1c(Br)cc2c(c1C(C)(C)O)OCC2(C)C>>Cc1c(Br)cc2c(c1C(C)C)OCC2(C)C -US20080293742A1,7,COc1nc([N+](=O)[O-])cnc1NS(=O)(=O)c1cccc(Cl)c1F>>COc1nc(N)cnc1NS(=O)(=O)c1cccc(Cl)c1F -US08163773B2,6,COCCCN1C(=O)C(C)(C)Oc2ccc(N(C(=O)[C@@H]3C[C@H](NC(=O)Cc4ccccc4)CN(C(=O)OCC4c5ccccc5-c5ccccc54)C3)C3CC3)cc21>>COCCCN1C(=O)C(C)(C)Oc2ccc(N(C(=O)[C@H]3CNC[C@@H](NC(=O)Cc4ccccc4)C3)C3CC3)cc21 -US05015755,3,C[Mg+].O=CCc1c2ccccc2cc2ccccc12>>CC(O)Cc1c2ccccc2cc2ccccc12 -US20140121198A1,4,CC(=O)O.Nc1cnc2ccsc2c1N[C@H]1CC[C@H](CO)OC1>>Cc1nc2cnc3ccsc3c2n1[C@H]1CC[C@H](CO)OC1 -US08853243B2,6,COC(=O)[C@H]1C/C(=C/c2ccccc2)CC[C@@H]1C(=O)N1CCN(c2ccccc2)CC1>>O=C(O)[C@H]1C/C(=C/c2ccccc2)CC[C@@H]1C(=O)N1CCN(c2ccccc2)CC1 -US07135487B2,7,CC(=O)c1cccc(-c2ccc(C(C)CNS(=O)(=O)C(C)C)cc2)c1>>CC(O)c1cccc(-c2ccc(C(C)CNS(=O)(=O)C(C)C)cc2)c1 -US20100076048A1,6,CCOC(=O)Cc1ccc(N2C(=O)c3c(c(OCC)c4ccccc4c3OCC)C2=O)c(Cl)c1>>CCOc1c2c(c(OCC)c3ccccc13)C(=O)N(c1ccc(CC(=O)O)cc1Cl)C2=O -US08242109B2,6,CC(C)(C)OC(=O)Nc1ccc(C2=NC(Cc3ccccc3Br)C(=O)Nc3ccc(Cl)cc32)cc1>>Nc1ccc(C2=NC(Cc3ccccc3Br)C(=O)Nc3ccc(Cl)cc32)cc1 -US07728029B2,2,NC1C2CC3CC1CC(O)(C3)C2.O=C(O)c1cnn(C2CC2)c1C(F)(F)F>>O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnn(C2CC2)c1C(F)(F)F -US20140154179A1,6,CCOC(=O)c1csc(N2CCC(O)CC2)n1>>O=C(O)c1csc(N2CCC(O)CC2)n1 -US20110144090A1,1,CNC(=O)Cc1cn(C)c2ccc(F)c(O)c12.Clc1cccc(CBr)c1>>CNC(=O)Cc1cn(C)c2ccc(F)c(OCc3cccc(Cl)c3)c12 -US20040220185A1,3,C#C[Si](C)(C)C.CC(C)(C)OC(=O)N1CCN(c2ccc(I)cn2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(C#C[Si](C)(C)C)cn2)CC1 -US05084466,2,N#Cc1ccc(CCN)cc1.O=C(O)c1ccc(O)cc1>>N#Cc1ccc(CCNC(=O)c2ccc(O)cc2)cc1 -US06908930B2,3,O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1.O=Cc1ccc(C(=O)N2CCOCC2)[nH]1>>O=C1Nc2ncnc(Nc3ccc(F)c(Cl)c3)c2C1=Cc1ccc(C(=O)N2CCOCC2)[nH]1 -US20110212963A1,1,O=C1NC(=O)c2ccccc21.OCCC1CCN(c2cccc(-c3ccc(F)cc3)n2)CC1>>O=C1c2ccccc2C(=O)N1CCC1CCN(c2cccc(-c3ccc(F)cc3)n2)CC1 -US20040067955A1,2,CC(C)n1nc(-c2cc(C(=O)O)cnc2-c2ccccc2)ccc1=O.CO>>COC(=O)c1cnc(-c2ccccc2)c(-c2ccc(=O)n(C(C)C)n2)c1 -US20150105429A1,1,CC(C)CBr.C[C@@H](NS(=O)(=O)Cc1ccccc1)c1ccc(Br)cc1>>CC(C)CN([C@H](C)c1ccc(Br)cc1)S(=O)(=O)Cc1ccccc1 -US20120196848A1,3,CB(O)O.CC(C)c1c(Br)sc2c1O[C@@H](C)CN(C(=O)OC(C)(C)C)C2>>Cc1sc2c(c1C(C)C)O[C@@H](C)CN(C(=O)OC(C)(C)C)C2 -US20040127492A1,6,CCOC(=O)c1c2c(nn1CCCO)-c1cn[nH]c1CC2>>O=C(O)c1c2c(nn1CCCO)-c1cn[nH]c1CC2 -US20080318963A1,2,CCOC(=O)Nc1nc2cc(F)c(F)cc2nc1OC.Cc1cccc(N2CCNCC2)c1>>COc1nc2cc(F)c(F)cc2nc1NC(=O)N1CCN(c2cccc(C)c2)CC1 -US20060116356A1,6,COC(=O)CCSC1c2c(c(O)c3ncccc3c2OC)C(=O)N1Cc1ccc(F)cc1>>COc1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2SCCC(=O)O -US20130116285A1,3,COC(=O)c1cc(Br)c(Oc2ccc(Cl)cc2)cc1F.COc1ncccc1B(O)O>>COC(=O)c1cc(-c2cccnc2OC)c(Oc2ccc(Cl)cc2)cc1F -US05395817,1,FC(F)(F)c1cnc(Cl)c(Cl)c1.Nc1cccc2[nH]ccc12>>Nc1cccc2c1ccn2-c1ncc(C(F)(F)F)cc1Cl -US08557805B2,6,CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)nc3)cc(CC)c2[nH]1>>CCc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C(=O)O)[nH]c12 -US20100228029A1,6,CCOC(=O)/C=C/c1ccc(OCc2nc(C)c(C)nc2C)c(OC)c1>>COc1cc(/C=C/C(=O)O)ccc1OCc1nc(C)c(C)nc1C -US20080176832A1,6,CC(C)(C)OC(=O)N1CCc2cn(-c3ccc(C(N)=O)cc3)nc2CC1>>NC(=O)c1ccc(-n2cc3c(n2)CCNCC3)cc1 -US08598208B2,1,CCNCC.CCOC(=O)c1cnc(Cl)c(Cl)c1>>CCOC(=O)c1cnc(N(CC)CC)c(Cl)c1 -US04476132,6,CCCC(=O)c1cc2c(=O)cc(C(=O)OC)[nH]c2c(C)c1C>>CCCC(=O)c1cc2c(=O)cc(C(=O)O)[nH]c2c(C)c1C -US20120035139A9,1,COC(=O)c1ccccc1Br.Nc1cc([C@@H]2CNC(=O)C2)ccc1Cl>>COC(=O)c1ccccc1Nc1cc([C@@H]2CNC(=O)C2)ccc1Cl -US20090318690A1,1,CC(C)(C)OC(=O)N1CCC(CCc2noc3c(COS(C)(=O)=O)c(OCc4ccc(C#N)cc4)ccc23)CC1.CNC>>CN(C)Cc1c(OCc2ccc(C#N)cc2)ccc2c(CCC3CCN(C(=O)OC(C)(C)C)CC3)noc12 -US04256759,2,N#CCC(=O)O.Nc1ccccc1>>N#CCC(=O)Nc1ccccc1 -US08592399B2,6,COC(=O)C1CN(Cc2ccc(-c3ccc(C(=O)C=C(C)c4cccc(C(F)(F)F)c4)cc3)cc2)C1>>CC(=CC(=O)c1ccc(-c2ccc(CN3CC(C(=O)O)C3)cc2)cc1)c1cccc(C(F)(F)F)c1 -US20100273781A1,2,Cc1cc(C)n(CC(=O)O)n1.O=[N+]([O-])c1ccccc1N1CCNCC1>>Cc1cc(C)n(CC(=O)N2CCN(c3ccccc3[N+](=O)[O-])CC2)n1 -US20090062311A1,6,CCOC(=O)C12CC1C=CCCCCN(C)C(=O)C1CC(Oc3cc(-c4nc(C(C)C)cs4)nc4cc(OC)ccc34)CC1C(=O)N2>>COc1ccc2c(OC3CC4C(=O)NC5(C(=O)O)CC5C=CCCCCN(C)C(=O)C4C3)cc(-c3nc(C(C)C)cs3)nc2c1 -US20110092505A1,6,COC(=O)c1cc(Cl)nc(N2CCN(C(=O)OC(C)(C)C)CC2)c1>>CC(C)(C)OC(=O)N1CCN(c2cc(C(=O)O)cc(Cl)n2)CC1 -US20070106095A1,7,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2cc(OS(C)(=O)=O)ccc2o1>>CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1cc2cc(OS(C)(=O)=O)ccc2o1 -US20110124634A1,1,ClCc1cc2c(cc1Cl)OCO2.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1cc2c(cc1Cl)OCO2 -US20130059830A1,6,CC(C)(C)OC(=O)N1CC(c2cc(-c3ccc(F)cc3)nn2-c2ncccn2)CCC1CCc1ccccc1>>Fc1ccc(-c2cc(C3CCC(CCc4ccccc4)NC3)n(-c3ncccn3)n2)cc1 -US04735959,2,CCOC(=O)c1ccc(CC(=O)Cl)cc1.NC(c1ccc(Cl)cc1)c1ccccc1N1CCCCC1>>CCOC(=O)c1ccc(CC(=O)NC(c2ccc(Cl)cc2)c2ccccc2N2CCCCC2)cc1 -US07148226B2,9,CC(O)c1cccc(F)c1O>>CCc1cccc(F)c1O -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)NCc2ccccc2)cc1C.FC(F)(F)c1cnc(Cl)c(Cl)c1>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1C -US20090093491A1,1,Brc1cnc(CCCCn2cncn2)cn1.OCc1coc(C=Cc2ccc(C(F)(F)F)cc2)n1>>FC(F)(F)c1ccc(/C=C/c2nc(COc3cnc(CCCCn4cncn4)cn3)co2)cc1 -US04968699,2,CN(C)c1ccc(C(=O)O)cc1.NCCc1c2n(c3ccccc13)C(=O)CCC2>>CN(C)c1ccc(C(=O)NCCc2c3n(c4ccccc24)C(=O)CCC3)cc1 -US04798620,9,CCOC(=O)CN1C(=O)COc2cc(F)ccc21.N>>NC(=O)CN1C(=O)COc2cc(F)ccc21 -US20080113966A1,9,CC(C)(C)OC(=O)N1CCC(NC(=O)OCc2ccccc2)(C(=O)O)CC1.N>>CC(C)(C)OC(=O)N1CCC(NC(=O)OCc2ccccc2)(C(N)=O)CC1 -US20090270363A1,6,CCN(C(C)=O)c1ccc(C#N)cc1>>CCNc1ccc(C#N)cc1 -US09113630B2,6,CCOC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl>>O=C(O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl -US05473041,1,C=CCCBr.O=[N+]([O-])c1ccc(-c2ccc([N+](=O)[O-])cc2O)cc1>>C=CCCOc1cc([N+](=O)[O-])ccc1-c1ccc([N+](=O)[O-])cc1 -US20130338142A1,7,COC(=O)C(C)(C)c1ccc([N+](=O)[O-])cc1>>CC(C)(CO)c1ccc([N+](=O)[O-])cc1 -US20100273819A1,6,CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)OC>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)O -US20070043074A1,7,Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)O)cc1>>Cc1ccc(-c2nc3ccc(C)cn3c2CCO)cc1 -US06194406B1,6,COC(=O)c1cc(Cn2ccnn2)ccc1OC>>COc1ccc(Cn2ccnn2)cc1C(=O)O -US20100120785A1,1,Cc1nn(C)cc1C=O.Clc1nccnc1N1CCNCC1>>Cc1nn(C)cc1CN1CCN(c2nccnc2Cl)CC1 -US20150152047A1,6,CCOC(=O)c1ccc(CN2CCC[C@H](NC(=O)OC(C)(C)C)C2)c(OC(F)(F)F)c1>>CC(C)(C)OC(=O)N[C@H]1CCCN(Cc2ccc(C(=O)O)cc2OC(F)(F)F)C1 -US07563894B2,3,COC(=O)c1ccc(Nc2ncc(Br)cn2)cc1.COc1ccc(B(O)O)cc1>>COC(=O)c1ccc(Nc2ncc(-c3ccc(OC)cc3)cn2)cc1 -US20090233930A9,2,CN(C)S(=O)(=O)Cl.CN1C(=O)C(c2cccc(O)c2)(c2cccc(Br)c2)NC1=S>>CN1C(=O)C(c2cccc(Br)c2)(c2cccc(OS(=O)(=O)N(C)C)c2)NC1=S -US09006230B2,4,CC(C)(C)OC(=O)N1C[C@@H](NOCc2ccccc2)CC[C@@H]1C#N.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1C[C@@H](NOCc2ccccc2)CC[C@@H]1c1nnn[nH]1 -US20110319456A1,6,CCOC(=O)CNC(=O)Nc1nc2ccccc2s1>>O=C(O)CNC(=O)Nc1nc2ccccc2s1 -US20080058356A1,9,Clc1cc(Cl)nc(-c2ccco2)n1.[NH4+]>>Nc1cc(Cl)nc(-c2ccco2)n1 -US20130101516A1,1,C#CCN(CC#C)CC#C.CCCCCCCCCCCCOc1ccc(CBr)cc1>>C#CC[N+](CC#C)(CC#C)Cc1ccc(OCCCCCCCCCCCC)cc1 -US20150259354A1,2,CC(C)(C)OC(=O)N1CC(C(=O)O)C1.CNOC>>CON(C)C(=O)C1CN(C(=O)OC(C)(C)C)C1 -US20070082880A1,3,C#Cc1ccccn1.N#Cc1cnc2sc(I)cc2c1Nc1ccc2[nH]ccc2c1>>N#Cc1cnc2sc(C#Cc3ccccn3)cc2c1Nc1ccc2[nH]ccc2c1 -US08338426B2,2,CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2F)CC1.O=C(O)c1ccccc1-c1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2F)CC1 -US05591762,6,CCOc1nc2c(C)cc(-c3cn(CC4CC4)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCOc1nc2c(C)cc(-c3cn(CC4CC4)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US04988723,7,CCC1(CC)CC(=O)c2cc(C#N)ccc2O1>>CCC1(CC)CC(O)c2cc(C#N)ccc2O1 -US20110076291A1,2,O=C(C1CCNCC1)N1CCCC1.O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2>>O=C(c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2)N1CCC(C(=O)N2CCCC2)CC1 -US20150210675A1,2,CCCCCCCCCCCc1cc(C(=O)NN)ccc1C.N#CC1(C(=O)O)CC1>>CCCCCCCCCCCc1cc(C(=O)NNC(=O)C2(C#N)CC2)ccc1C -US08828987B2,6,COC(=O)c1cc(F)cnc1N1CC(Nc2ccc(F)cc2C)C1>>Cc1cc(F)ccc1NC1CN(c2ncc(F)cc2C(=O)O)C1 -US08673893B2,7,CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(C(=O)c5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1>>CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(C(O)c5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1 -US20120040953A1,3,CC(C)(C)OC(=O)N[C@H]1CN(c2ncc(Br)cn2)C[C@@H]1N1CCCCC1=O.CC(C)OC(=O)N1CCC(C(C)Oc2ccc(B3OC(C)(C)C(C)(C)O3)cn2)CC1>>CC(C)OC(=O)N1CCC([C@H](C)Oc2ccc(-c3cnc(N4C[C@H](NC(=O)OC(C)(C)C)[C@@H](N5CCCCC5=O)C4)nc3)cn2)CC1 -US07074820B2,2,Cc1c(N)cccc1OCCc1ccc(C#N)cc1.O=S(=O)(Cl)c1ccccc1>>Cc1c(NS(=O)(=O)c2ccccc2)cccc1OCCc1ccc(C#N)cc1 -US05827865,6,CCOC(=O)C(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)OCC>>CCOC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O -US04124593,1,CCO.O=C1c2ccc(Cl)cc2C(=O)N1c1ccc([N+](=O)[O-])cc1CI>>CCOCc1cc([N+](=O)[O-])ccc1N1C(=O)c2ccc(Cl)cc2C1=O -US20130040930A1,1,Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3C#N)CC2)c(C)c1.O=C1CCCN1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCC4=O)cc3C#N)CC2)c(C)c1 -US06706878B2,1,Clc1ccnc2c1CC1(CN3CCC1CC3)O2.NCCN>>NCCNc1ccnc2c1CC1(CN3CCC1CC3)O2 -US05958954,3,C#C[Si](C)(C)C.CC1(C)CC(=O)c2cc(OS(=O)(=O)C(F)(F)F)c(F)cc2S1>>CC1(C)CC(=O)c2cc(C#C[Si](C)(C)C)c(F)cc2S1 -US20080146636A1,1,Cc1ccc2c(c1)nc(C(C)(C)O)n2C1CCC(N)CC1.O=CC1Cc2ccc(Cl)cc2C1>>Cc1ccc2c(c1)nc(C(C)(C)O)n2[C@@H]1CC[C@H](NCC2Cc3ccc(Cl)cc3C2)CC1 -US04444867,2,CC(=O)Nc1cccc2c(OC(C)=O)c(S(=O)(=O)O)ccc12.CC(C)(C)N>>CC(=O)Nc1cccc2c(OC(C)=O)c(S(=O)(=O)NC(C)(C)C)ccc12 -US04049812,9,N.O=C(O)c1nc(CCl)n(-c2ccccc2C(=O)c2ccccn2)n1>>NC(=O)c1nc(CCl)n(-c2ccccc2C(=O)c2ccccn2)n1 -US20080287479A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.COC(=O)c1cc([N+](=O)[O-])c(F)cc1F>>COC(=O)c1cc([N+](=O)[O-])c(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1F -US07858644B2,6,CCOC(=O)Cc1cc(CO[Si](C(C)C)(C(C)C)C(C)C)c(C)o1>>CCOC(=O)Cc1cc(CO)c(C)o1 -US20130023534A1,1,Cc1noc(N)c1C.Clc1ccnc(Cl)n1>>Cc1noc(Nc2ccnc(Cl)n2)c1C -US07572934B2,1,CCC[C@@H](CC(=O)OC)c1ccc(O)cc1.COc1ccc(F)c(-c2cc(CCl)ccc2C(C)(C)C)c1>>CCC[C@@H](CC(=O)OC)c1ccc(OCc2ccc(C(C)(C)C)c(-c3cc(OC)ccc3F)c2)cc1 -US08222274B2,6,Cc1c(C(=O)OCc2ccccc2)cc(CCCN2C(=O)c3ccccc3C2=O)n1CCc1ccc(F)cc1>>Cc1c(C(=O)OCc2ccccc2)cc(CCCN)n1CCc1ccc(F)cc1 -US06888029B2,1,Cc1cccc(C)c1N.O=[N+]([O-])c1ccccc1Cl>>Cc1cccc(C)c1Nc1ccccc1[N+](=O)[O-] -US20020032168A1,1,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(Cl)nc(C#N)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.NCC(c1cccc(Cl)c1)c1cccc(Cl)c1>>CC(=O)OC[C@H]1O[C@@H](n2cnc3c(NCC(c4cccc(Cl)c4)c4cccc(Cl)c4)nc(C#N)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O -US20070106095A1,7,CCC(CC)(c1ccc(OC2CCCCC2=O)c(C)c1)c1ccc2oc(C(=O)O)cc2c1>>CCC(CC)(c1ccc(OC2CCCCC2O)c(C)c1)c1ccc2oc(C(=O)O)cc2c1 -US06117884,3,C=Cc1ccccc1.Clc1ccc2c(Br)ccnc2c1>>Clc1ccc2c(C=Cc3ccccc3)ccnc2c1 -US20090264401A1,6,CCCSc1nc(N2CCC[C@@H](CC(=O)OC)C2)ncc1C(=O)NC1CCCCC1>>CCCSc1nc(N2CCC[C@@H](CC(=O)O)C2)ncc1C(=O)NC1CCCCC1 -US20030158235A1,1,O=C(O)c1ccc(Cl)nc1.OCc1ccccc1>>O=C(O)c1ccc(OCc2ccccc2)nc1 -US07786109B2,6,CC(C)(C)OC(=O)N1CCC(Oc2cnc3c(c2)cc2n3CCNC2=O)CC1>>O=C1NCCn2c1cc1cc(OC3CCNCC3)cnc12 -US07432283B2,2,Cc1cc(C)c(N)c(Cl)c1.O=C(Cl)CCCCCl>>Cc1cc(C)c(NC(=O)CCCCCl)c(Cl)c1 -US07884099B2,1,CC(C)(C)OC(=O)N1CCC(NC2CCNCC2)CC1.COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>COc1c(N2CCC(NC3CCN(C(=O)OC(C)(C)C)CC3)CC2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US06838567B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)[C@@H]1CCN1>>CC(C)(C)OC(=O)N1CC[C@H]1C(=O)O -US20140228357A1,2,CN(C)CCN.O=C(O)CCOc1ccc(C23CC4CC(CC(C4)C2)C3)cc1>>CN(C)CCNC(=O)CCOc1ccc(C23CC4CC(CC(C4)C2)C3)cc1 -US20100261755A1,3,COC(=O)c1ccnc(Cl)c1.Fc1cccc(F)c1C[Zn+]>>COC(=O)c1ccnc(Cc2c(F)cccc2F)c1 -US20110112127A1,6,COC(=O)c1cc(C(=O)OC)n(Cc2ccc(OC)cc2)n1>>COC(=O)c1cc(C(=O)O)nn1Cc1ccc(OC)cc1 -US20060189625A1,1,BrCCC1CCCCC1.COc1ccc(N2CCNCC2)cc1F>>COc1ccc(N2CCN(CCC3CCCCC3)CC2)cc1F -US04822404,2,CC(=O)OC(C)=O.Cc1cc(C)n2nc(NS(=O)(=O)c3c(Cl)cccc3Cl)nc2n1>>CC(=O)N(c1nc2nc(C)cc(C)n2n1)S(=O)(=O)c1c(Cl)cccc1Cl -US20130026909A1,3,Brc1cccc(Br)c1.CC(=O)n1c2ccccc2c2cc(B3OC(C)(C)C(C)(C)O3)ccc21>>CC(=O)n1c2ccccc2c2cc(-c3cccc(Br)c3)ccc21 -US04997836,6,CCOCC1CN(C(=O)c2cc(OC)c(OC)c(OC)c2)CCN1Cc1ccccc1>>CCOCC1CN(C(=O)c2cc(OC)c(OC)c(OC)c2)CCN1 -US20040067999A1,2,COCC(C)O.Cc1ccc(S(=O)(=O)Cl)cc1>>COCC(C)OS(=O)(=O)c1ccc(C)cc1 -US20110112096A1,1,C1COCCN1.Cc1cc(Nc2nc(Nc3cc(C)c(C4CCC(=O)CC4)cc3C)ncc2C(F)(F)F)n[nH]1>>Cc1cc(Nc2nc(Nc3cc(C)c([C@@H]4CC[C@H](N5CCOCC5)CC4)cc3C)ncc2C(F)(F)F)n[nH]1 -US20110105509A1,6,CCC(O)(CC)Cn1nc(-c2c(C)n(CC(=O)OC(C)(C)C)c3ccc(F)cc23)c2ccccc2c1=O>>CCC(O)(CC)Cn1nc(-c2c(C)n(CC(=O)O)c3ccc(F)cc23)c2ccccc2c1=O -US04362744,2,CC1(C)[C@H](C=C(Cl)Cl)[C@@H]1C(=O)Cl.O[C@@H]1C[C@@H](Cc2ccc(F)cc2)c2ccccc21>>CC1(C)[C@H](C=C(Cl)Cl)[C@@H]1C(=O)O[C@@H]1C[C@@H](Cc2ccc(F)cc2)c2ccccc21 -US07994171B2,2,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)c(OC)cc3C)c(F)c12.NC1(c2ncc(F)cn2)CC1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5ncc(F)cn5)CC4)c(OC)cc3C)c(F)c12 -US04022832,2,NCC(=O)O.Nc1ccc(Br)cc1C(=NCCO)c1ccccc1F>>NCC(=O)Nc1ccc(Br)cc1C(=NCCO)c1ccccc1F -US07468391B2,3,C#Cc1cc(OC)c2c(c1)C(C)(C)CCC2N(C)C1CC1.COC(=O)Cc1ccc(I)cc1>>COC(=O)Cc1ccc(C#Cc2cc(OC)c3c(c2)C(C)(C)CCC3N(C)C2CC2)cc1 -US20030149051A1,4,CC(=O)c1c(-c2ccccc2)noc1C.COC(OC)N(C)C.N=C(N)N>>Cc1onc(-c2ccccc2)c1-c1ccnc(N)n1 -US20090227591A1,2,CC(=O)Cl.CCOC(=O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)ccc1N>>CCOC(=O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)ccc1NC(C)=O -US20100221182A1,1,FCCBr.N#Cc1cccc(O)c1>>N#Cc1cccc(OCCF)c1 -US20100298285A1,2,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O.Cc1ccc2c(c1NC(=O)Cc1ccc(C(F)(F)F)c(F)c1)CCNC2>>Cc1ccc2c(c1NC(=O)Cc1ccc(C(F)(F)F)c(F)c1)CCN(C(=O)[C@H]1CCCN1C(=O)OC(C)(C)C)C2 -US09108936B2,1,COc1cc(N2CCOCC2)cc(C(C)C)c1C(N)=O.Clc1ccc(CBr)cc1>>COc1cc(N2CCOCC2)cc(C(C)C)c1C(=O)NCc1ccc(Cl)cc1 -US07309701B2,2,NCc1ccncc1.O=C(O)c1cc(-c2ccncc2)n[nH]c1=O>>O=C(NCc1ccncc1)c1cc(-c2ccncc2)n[nH]c1=O -US05854261,1,COc1cc(N)c(Cl)cc1-c1noc(C2CCNCC2)n1.CS(=O)(=O)OCC1CCCO1>>COc1cc(N)c(Cl)cc1-c1noc(C2CCN(CC3CCCO3)CC2)n1 -US20100240638A1,2,C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)C1(CCCCCCCCCCCC(=O)OC)CC1.CC(C)(C)OC(=O)N1C[C@H](OC(=O)N2Cc3cccc(F)c3C2)C[C@H]1C(=O)O>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(F)c3C2)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)C1(CCCCCCCCCCCC(=O)OC)CC1 -US06126932,4,CC(=O)CCCN1C(=O)c2ccccc2C1=O.NNc1ccc(NC(=O)c2ccc(F)cc2)cc1>>Cc1[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc2c1CCN1C(=O)c2ccccc2C1=O -US06410556B1,6,CCOC1(OCC)CCN([C@@H](C)c2ccccc2)[C@@H](CN2C(=O)c3ccccc3C2=O)C1>>CCOC1(OCC)CCN([C@@H](C)c2ccccc2)[C@@H](CN)C1 -US20140315881A1,6,Cc1cc(OCc2ccccc2)ccc1C(NC(=O)Cc1ccc2oc(C(c3c(C)noc3C)N3CC(NC(=O)OC(C)(C)C)C3)cc2c1)c1ccccc1>>Cc1cc(O)ccc1C(NC(=O)Cc1ccc2oc(C(c3c(C)noc3C)N3CC(NC(=O)OC(C)(C)C)C3)cc2c1)c1ccccc1 -US20120277224A1,6,COC(=O)c1ccc2c(c1)OC(F)(F)O2>>O=C(O)c1ccc2c(c1)OC(F)(F)O2 -US20060069126A1,6,CC(=O)OC1CC(F)(N2C(=O)c3cccc(N)c3C2=O)C(=O)NC1=O>>Nc1cccc2c1C(=O)N(C1(F)CC(O)C(=O)NC1=O)C2=O -US07329679B2,1,CI.COC(=O)CCCCCOc1cc2nc(-c3ccccc3)n(-c3ccc(C)cc3)c2cc1O>>COC(=O)CCCCCOc1cc2nc(-c3ccccc3)n(-c3ccc(C)cc3)c2cc1OC -US04550107,1,CCN(CC)C1CCCCNC1.O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21>>CCN(CC)C1CCCCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)C1 -US20150284395A1,1,CC(C)I.COC(=O)c1ccc2[nH]ncc2c1>>COC(=O)c1ccc2c(cnn2C(C)C)c1 -US08063071B2,7,CC(C)(C)OC(=O)N1CC=C(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1>>CC(C)(C)OC(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1 -US20130040930A1,1,CN1C(=O)CNC1=O.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2F)CC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CC(=O)N(C)C3=O)cc2F)CC1 -US08614242B2,2,Cc1cccc(CC2CCCN2)c1.Cn1nc(C(F)F)c(C(=O)Cl)c1F>>Cc1cccc(CC2CCCN2C(=O)c2c(C(F)F)nn(C)c2F)c1 -US04460579,1,CCOC(=O)C(=O)CCc1ccccc1.C[Si](C)(C)CCOC(=O)CN1C(=O)C(N)CS[C@@H]1c1ccccc1>>CCOC(=O)C(CCc1ccccc1)NC1CS[C@H](c2ccccc2)N(CC(=O)OCC[Si](C)(C)C)C1=O -US07560569B2,2,CC(C)(C)OC(=O)c1ccc(N)cc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>CC(C)(C)OC(=O)c1ccc(NC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)cc1 -US20080280855A1,1,Cc1nc2c(O)c(CC[C@@H](O)c3ccccc3Cl)c(C(=O)N(C)C)cc2n1C>>Cc1nc2c3c(c(C(=O)N(C)C)cc2n1C)CC[C@@H](c1ccccc1Cl)O3 -US20130281657A1,4,CC(C)(C)OC(=O)CNC(N)=S.O=CC(Br)C=O>>CC(C)(C)OC(=O)CNc1ncc(C=O)s1 -US20100256097A1,1,CC(C)(O)c1ccc(-c2cc(C(N)=O)c(N)s2)c(F)c1.O=C(O)CN(Cc1cccc(Br)n1)C(=O)OCc1ccccc1>>CC(C)(O)c1ccc(-c2cc(C(N)=O)c(Nc3cccc(CN(CC(=O)O)C(=O)OCc4ccccc4)n3)s2)c(F)c1 -US20100152441A1,1,CC(C)(C)OC(=O)NC1CCN(CCOS(C)(=O)=O)CC1.O=c1ccc2ccc(Cl)nc2[nH]1>>CC(C)(C)OC(=O)NC1CCN(CCn2c(=O)ccc3ccc(Cl)nc32)CC1 -US20080255153A1,2,O=C(O)c1cnccn1.[NH3+]CCNC(=O)c1cnn2cc(Cc3ccc(Cl)c(Cl)c3)cnc12>>O=C(NCCNC(=O)c1cnn2cc(Cc3ccc(Cl)c(Cl)c3)cnc12)c1cnccn1 -US20140329862A1,1,CCCC(=O)c1ccc(C(=O)OCC)cc1.Nc1cnc(-c2ccc(C(F)(F)F)cc2)nc1>>CCCC(Nc1cnc(-c2ccc(C(F)(F)F)cc2)nc1)c1ccc(C(=O)OCC)cc1 -US05741791,6,COC(=O)CC1CCN(CCCN2c3ccccc3CCc3ccccc32)C1>>O=C(O)CC1CCN(CCCN2c3ccccc3CCc3ccccc32)C1 -US20050038035A1,7,CC(C)(C)OC(=O)Nc1nc(CCOc2ccc([N+](=O)[O-])cn2)cs1>>CC(C)(C)OC(=O)Nc1nc(CCOc2ccc(N)cn2)cs1 -US20090069373A1,3,FC(F)(F)c1cccc2c(Br)c(Cc3ccccc3)cnc12.OB(O)c1cccc2[nH]ccc12>>FC(F)(F)c1cccc2c(-c3cccc4[nH]ccc34)c(Cc3ccccc3)cnc12 -US05672618,1,ClCCCBr.c1ccc2c(c1)ccn2C1CCNCC1>>ClCCCN1CCC(n2ccc3ccccc32)CC1 -US08828987B2,1,COC(=O)c1cc(F)cnc1Cl.Cc1cc(F)ccc1NC1CNC1>>COC(=O)c1cc(F)cnc1N1CC(Nc2ccc(F)cc2C)C1 -US20150005277A1,2,CN1CC=C(C(=O)O)CC1.NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn(C2CCCNC2)c1N>>CN1CC=C(C(=O)N2CCCC(n3nc(-c4ccc(Oc5ccccc5)cc4)c(C(N)=O)c3N)C2)CC1 -US20130190330A1,1,BrCc1ccccc1Br.O=c1[nH]nc(-c2ccc(Cl)cc2)n1C1CC1>>O=c1n(Cc2ccccc2Br)nc(-c2ccc(Cl)cc2)n1C1CC1 -US07262302B2,1,CN(C)CCCCl.OCc1nc2c(s1)-c1ccccc1Sc1ccc(F)cc1-2>>CN(C)CCCOCc1nc2c(s1)-c1ccccc1Sc1ccc(F)cc1-2 -US06350749B1,1,N=C(N)NN.NC(=O)c1coc2c1C(=O)CC(c1ccccc1)C2>>N=C(N)N/N=C1\CC(c2ccccc2)Cc2occ(C(N)=O)c21 -US06350749B1,1,N=C(N)NN.O=C1CC(c2cc(Cl)sc2Cl)Cc2nncc(C(F)(F)F)c21>>N=C(N)NN=C1CC(c2cc(Cl)sc2Cl)Cc2nncc(C(F)(F)F)c21 -US20140155382A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)[C@@H]1CCCN1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O -US20070117852A1,1,CC(=O)C(C)Br.O=C(Nc1ccccc1O)c1cccnc1Cl>>CC(=O)C(C)Oc1ccccc1NC(=O)c1cccnc1Cl -US20140066459A1,3,CC(=O)N1c2ccc(Br)cc2[C@H](N)C[C@@H]1C.COCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COCCn1cc(-c2ccc3c(c2)[C@H](N)C[C@H](C)N3C(C)=O)cn1 -US05866564,2,COc1ccc(CS[C@H]2C[C@@H](C(=O)O)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1.OCCN1CCNCC1>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(CCO)CC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1 -US05789595,7,CCOC(=O)CCN1CCc2ccc([N+](=O)[O-])cc2C1C>>CCOC(=O)CCN1CCc2ccc(N)cc2C1C -US07253198B2,2,COC(=O)c1cc(N)cc(Br)c1.O=C(Cl)CCCCl>>COC(=O)c1cc(Br)cc(NC(=O)CCCCl)c1 -US07414060B2,1,Cc1ccc(Br)c(C(=O)Nc2ccn(C)n2)n1.Cn1ccc(N)n1>>Cc1ccc(Nc2ccn(C)n2)c(C(=O)Nc2ccn(C)n2)n1 -US08383654B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cn[nH]c1>>Cc1cnn(C(=O)OC(C)(C)C)c1 -US05238599,9,N#C[Cu].Nc1ccc(Br)cc1F>>N#Cc1ccc(N)c(F)c1 -US20030187026A1,1,Brc1cncc(Br)c1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2cncc(Br)c2)CC1 -US20040157866A1,2,O=C(O)Cc1ccccn1.O=[N+]([O-])c1ccc2c(c1)CCN2>>O=C(Cc1ccccn1)N1CCc2cc([N+](=O)[O-])ccc21 -US20090306388A1,1,Clc1nccc2[nH]cnc12.NCc1ccccc1>>c1ccc(CNc2nccc3[nH]cnc23)cc1 -US20140018356A1,7,COC1(OC)CCOCC1=O>>COC1(OC)CCOC[C@@H]1O -US09085578B2,2,COc1ccc(CNCc2cccc(Br)n2)c(OC)c1.O=CO>>COc1ccc(CN(C=O)Cc2cccc(Br)n2)c(OC)c1 -US07915281B2,1,C#CCN.Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C>>C#CCNc1c(C)c(C)nc(Cl)c1[N+](=O)[O-] -US20140309225A1,7,CC(C)C(OC(=O)c1ccc([N+](=O)[O-])cc1)[C@H](C)NC(=O)OC(C)(C)C>>CC(C)C(O)[C@H](C)NC(=O)OC(C)(C)C -USRE043878E1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1ncc2cc(Oc3ccc([N+](=O)[O-])cc3F)c(-c3cn[nH]c3)cc21>>Cn1ncc2cc(Oc3ccc([N+](=O)[O-])cc3F)c(-c3cnn(C(=O)OC(C)(C)C)c3)cc21 -US04847260,2,CCCCC(CC)CO.O=C(O)c1cccnc1>>CCCCC(CC)COC(=O)c1cccnc1 -US20120196857A9,2,CC(=O)Cl.CC(C)(C)OC(=O)N1CCC2(CC[C@H](N)c3ccccc32)CC1>>CC(=O)N[C@H]1CCC2(CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21 -US20150232443A1,2,CC1(N)CCC1.CCOC(=O)N1C2CCC1CC(N1CCC(OC)(C(=O)O)CC1)C2>>CCOC(=O)N1C2CCC1CC(N1CCC(OC)(C(=O)NC3(C)CCC3)CC1)C2 -US20090324581A1,2,CC(C)(C)OC(=O)CCN(CC(=O)O)C(=O)OC(C)(C)C.FC(F)(F)c1sc(COc2ccc3c(c2)OCCN3)cc1-c1ccccc1>>CC(C)(C)OC(=O)CCN(CC(=O)N1CCOc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21)C(=O)OC(C)(C)C -US20150210703A1,3,C[C@H]1CN(C(=O)OC(C)(C)C)C[C@H]1Nc1c(C(N)=O)cnn2cc(Br)nc12.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>C[C@H]1CN(C(=O)OC(C)(C)C)C[C@H]1Nc1c(C(N)=O)cnn2cc(-c3cnn(C)c3)nc12 -US20130029980A1,7,Cc1ccc([N+](=O)[O-])c(NCC(O)Cc2ccc(Cl)cc2)c1>>Cc1ccc(N)c(NCC(O)Cc2ccc(Cl)cc2)c1 -US20120277237A1,2,CNCCC#Cc1ccccn1.O=C(Cl)c1ccccc1Cl>>CN(CCC#Cc1ccccn1)C(=O)c1ccccc1Cl -US04859229,2,Cn1c(C(F)(F)F)cc(=O)n(-c2cc(O)c(Cl)cc2F)c1=O.O=C=NCC1CCCCC1>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(OC(=O)NCC3CCCCC3)c(Cl)cc2F)c1=O -US20080293708A1,10,COC(=O)c1c([N+](=O)[O-])ccc(F)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1c([N+](=O)[O-])ccc(F)c1CBr -US08173650B2,2,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3(O)CCCNC3)n(C)c2n1.CS(=O)(=O)Cl>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3(O)CCCN(S(C)(=O)=O)C3)n(C)c2n1 -US07332511B2,6,COCOc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1>>Oc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1 -US05688817,2,C=CCOC(=O)c1ccc(C(=O)O)cc1.CC1(C)CCC(C)(C)c2cc(CO)ccc21>>C=CCOC(=O)c1ccc(C(=O)OCc2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 -US05234946,1,Cc1cccc(Cl)[n+]1[O-].OCc1ccccc1>>Cc1cccc(OCc2ccccc2)[n+]1[O-] -US07709479B1,3,C#CC(C)(C)O.CSc1ncnc2cc(OS(=O)(=O)C(F)(F)F)ccc12>>CSc1ncnc2cc(C#CC(C)(C)O)ccc12 -US07608633B2,1,CCCCCCCBr.c1ccc(COc2ccc3[nH]ccc3c2)cc1>>CCCCCCCn1ccc2cc(OCc3ccccc3)ccc21 -US08673942B2,9,CS(=O)(=O)c1ccc(Oc2cc(OCC3CCOCC3)c3[nH]c(C(=O)O)cc3c2)cc1.N>>CS(=O)(=O)c1ccc(Oc2cc(OCC3CCOCC3)c3[nH]c(C(N)=O)cc3c2)cc1 -US20090239941A1,6,CC(C)CC(=O)Oc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(N)=O)cc1OC(=O)CC(C)C>>CC(C)CC(=O)Oc1ccc(C[C@H]([NH3+])C(N)=O)cc1OC(=O)CC(C)C -US20070287721A1,1,C1CCNC1.CC(=O)c1c(-c2ccc(F)cc2)nn2c(Cl)cccc12>>CC(=O)c1c(-c2ccc(F)cc2)nn2c(N3CCCC3)cccc12 -US20040116458A1,6,CCOC(=O)C(=O)Nc1ccccc1>>O=C(O)C(=O)Nc1ccccc1 -US20040082607A1,2,C1CCNC1.CCCCOc1c(CN2C(=O)c3ccccc3C2=O)n(CCC(=O)O)c(=O)c2cc(Cl)c(Cl)cc12>>CCCCOc1c(CN2C(=O)c3ccccc3C2=O)n(CCC(=O)N2CCCC2)c(=O)c2cc(Cl)c(Cl)cc12 -US07022851B2,2,CC1NCCN(S(=O)(=O)c2ccccc2[N+](=O)[O-])C1=O.Cc1cn(CC(=O)O)c(=O)[nH]c1=O>>Cc1cn(CC(=O)N2CCN(S(=O)(=O)c3ccccc3[N+](=O)[O-])C(=O)C2C)c(=O)[nH]c1=O -US20030055071A1,3,C#CCO.COC(=O)c1nc(I)c2cccnc2c1OC(=O)c1ccccc1>>COC(=O)c1nc(C#CCO)c2cccnc2c1OC(=O)c1ccccc1 -US05728706,9,Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(Br)cn2)cc1.[C-]#N>>Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(C#N)cn2)cc1 -US20050032830A1,7,Cc1nc(Oc2ccccc2)c([N+](=O)[O-])c(NCCCCCCl)c1C>>Cc1nc(Oc2ccccc2)c(N)c(NCCCCCCl)c1C -US20120101096A1,1,CC(Br)C(=O)Nc1ccc(Cl)cc1.Oc1ccnc2ccccc12>>CC(Oc1ccnc2ccccc12)C(=O)Nc1ccc(Cl)cc1 -US07179823B1,1,BrCCBr.CCOC(=O)CCc1cn(Cc2ccc(O)cc2)nc1-c1ccccc1>>CCOC(=O)CCc1cn(Cc2ccc(OCCBr)cc2)nc1-c1ccccc1 -US20090270658A1,7,C=C(C)/C(C=O)=C\C=C(C)C>>C=C(C)/C(=C\C=C(C)C)CO -US20110257151A1,1,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(Br)c1)N2.CN1CCNCC1>>CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(N3CCN(C)CC3)c1)N2 -US20040024010A1,3,CC(=O)Nc1cccc(B(O)O)c1.COc1ccc(C=C2C(=O)Nc3ccccc32)cc1Br>>COc1ccc(C=C2C(=O)Nc3ccccc32)cc1-c1cccc(NC(C)=O)c1 -US20100331293A1,3,CCCC[Sn](CCCC)(CCCC)c1ncccc1C.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>Cc1cccnc1-c1nc2cc(F)cc(F)c2c(Cl)c1C -US20090170916A1,3,CCOC(=O)c1[nH]ccc1C.O=C(Cl)Cc1ccc(Cl)cc1>>CCOC(=O)c1[nH]cc(C(=O)Cc2ccc(Cl)cc2)c1C -US20150080393A1,6,Cc1ccn(-c2cc(Cl)ccc2[C@@H](Oc2cc(N3CCC4(CC3)C[C@@H](C(=O)OC(C)(C)C)N(C(=O)OCc3ccccc3)C4)nc(N)n2)C(F)(F)F)n1>>Cc1ccn(-c2cc(Cl)ccc2[C@@H](Oc2cc(N3CCC4(CC3)CN[C@H](C(=O)OC(C)(C)C)C4)nc(N)n2)C(F)(F)F)n1 -US20070173498A1,3,CC(=O)Nc1ccc2c(c1)CCCC2=O.O=CC(=O)O>>CC(=O)Nc1ccc2c(c1)CCC(=CC(=O)O)C2=O -US04771061,1,CCOC(=O)N1CCNCC1.O=C1C(Cl)=C(Cl)C(=O)c2ccccc21>>CCOC(=O)N1CCN(C2=C(Cl)C(=O)c3ccccc3C2=O)CC1 -US06015818,1,Cc1cc(Cl)c2cccc(O)c2n1.OCc1ccccn1>>Cc1cc(OCc2ccccn2)c2cccc(O)c2n1 -US20060094767A1,1,CC(C)(C)OC(=O)N1CCNCC1.ClCc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 -US20150087585A1,6,CCOC(=O)C1(c2coc(C3CC3)n2)CC1>>O=C(O)C1(c2coc(C3CC3)n2)CC1 -US20100152235A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1c(O)ccc2c1CCNC2>>Cc1c(O)ccc2c1CCN(C(=O)OC(C)(C)C)C2 -US08268822B2,2,Nc1cccc(-c2ccnc(NCCc3ccc(O)cc3)n2)c1.O=C(O)CCc1cccnc1>>O=C(CCc1cccnc1)Nc1cccc(-c2ccnc(NCCc3ccc(O)cc3)n2)c1 -US05635510,2,CCOc1cc(C(=O)Cl)cc(OCC)c1OCC.COc1ccc(C2(CCO)CCNC2)cc1OC>>CCOc1cc(C(=O)N2CCC(CCO)(c3ccc(OC)c(OC)c3)C2)cc(OCC)c1OCC -US05834506,2,CC(=O)OC(C)=O.Nc1ccc(CCC(=O)c2ccccc2)cc1>>CC(=O)Nc1ccc(CCC(=O)c2ccccc2)cc1 -US08013004B2,2,COC(=O)c1cccc(-c2cccnc2)c1.NN>>NNC(=O)c1cccc(-c2cccnc2)c1 -US20140371276A1,1,CI.Oc1nc(-c2ccc(Cl)cc2)sc1-c1nnn[nH]1>>Cn1nnnc1-c1sc(-c2ccc(Cl)cc2)nc1O -US20120022123A1,6,CCOC(=O)c1cc(-c2ccc(F)c(C#N)c2)c(-c2cc(F)cc(Cl)c2)s1>>N#Cc1cc(-c2cc(C(=O)O)sc2-c2cc(F)cc(Cl)c2)ccc1F -US20150218165A1,1,CC(C)(C)OC(=O)Nc1cc(F)c(F)cc1Br.CI>>CN(C(=O)OC(C)(C)C)c1cc(F)c(F)cc1Br -US20150238497A1,9,O[C@H](CCl)Cc1cccc(/C=C/c2c(Cl)cccc2Cl)c1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC[C@@H](O)Cc1cccc(/C=C/c2c(Cl)cccc2Cl)c1 -US09085583B2,1,CC(Br)C(=O)N1CCCC1.COC(=O)c1c(C)[nH]c2ccccc12>>COC(=O)c1c(C)n(C(C)C(=O)N2CCCC2)c2ccccc12 -US20150051171A1,1,Cn1nnn(-c2cccc(C3CC3)c2CBr)c1=O.Oc1ccn(-c2ccc(F)cc2)n1>>Cn1nnn(-c2cccc(C3CC3)c2COc2ccn(-c3ccc(F)cc3)n2)c1=O -US06271261B1,2,Nc1ccc([N+](=O)[O-])cc1O.O=C=NCCc1ccccc1>>O=C(NCCc1ccccc1)Nc1ccc([N+](=O)[O-])cc1O -US20100075961A1,6,COC(=O)C(C)(C)C(C)(C)c1ccc2c(cnn2-c2ccc(F)cc2)c1>>CC(C)(C(=O)O)C(C)(C)c1ccc2c(cnn2-c2ccc(F)cc2)c1 -US20100041892A1,2,CCCCCS(N)(=O)=O.COCCOc1ccc(CCCC(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1>>CCCCCS(=O)(=O)NC(=O)CCCc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl -US08455646B2,1,COC(=O)[C@@H](OS(C)(=O)=O)c1ccccc1.Nc1ccc(F)cc1>>COC(=O)[C@H](Nc1ccc(F)cc1)c1ccccc1 -US20120035164A1,1,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(C=O)c4)cc23)CC1.C[C@H](O)CN>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CNC[C@H](C)O)c4)cc23)CC1 -US07582773B2,6,CCCCCc1c(-c2ccccc2)n(Cc2ccccc2)c2ccc(-c3ccc(OCC(=O)OC)cc3)cc12>>CCCCCc1c(-c2ccccc2)n(Cc2ccccc2)c2ccc(-c3ccc(OCC(=O)O)cc3)cc12 -US04806538,6,Cn1cc(C[C@H]2NC(=O)[C@@H](CCC(=O)OCc3ccccc3)NC2=O)c2ccccc21>>Cn1cc(C[C@H]2NC(=O)[C@@H](CCC(=O)O)NC2=O)c2ccccc21 -US04250085,6,CCC[C@H](NC(=O)OCc1ccccc1)C(=O)NOP(C)(=O)O>>CCC[C@H](N)C(=O)NOP(C)(=O)O -US05635510,2,O=C(O)c1cc(F)c(F)c(F)c1.OCCC1(c2ccc(Cl)c(Cl)c2)CCNC1>>O=C(c1cc(F)c(F)c(F)c1)N1CCC(CCO)(c2ccc(Cl)c(Cl)c2)C1 -US04835180,1,C1=COCCC1.O=C(Nc1ccc(O)cc1)C(F)(F)F>>O=C(Nc1ccc(OC2CCCCO2)cc1)C(F)(F)F -US20080009490A1,1,N#CBr.O=C1CNCCN1Cc1ccc(F)cc1>>N#CN1CCN(Cc2ccc(F)cc2)C(=O)C1 -US20090203692A1,1,CC(C)=O.NCc1ccc(Cl)c(NC2=NC(=O)/C(=C/c3ccc4ncccc4c3)S2)c1>>CC(C)NCc1ccc(Cl)c(NC2=NC(=O)/C(=C/c3ccc4ncccc4c3)S2)c1 -US20120142705A1,2,CC(C)CC(C(=O)O)N1C(=O)C(=O)c2cc(Br)ccc21.Nc1nccs1>>CC(C)CC(C(=O)Nc1nccs1)N1C(=O)C(=O)c2cc(Br)ccc21 -US20060142247A1,2,CC1(C)C(=O)N(CCN)c2cc3[nH]c(-c4n[nH]c5ccccc45)nc3cc21.O=C(O)c1ccccc1>>CC1(C)C(=O)N(CCNC(=O)c2ccccc2)c2cc3[nH]c(-c4n[nH]c5ccccc45)nc3cc21 -US20120322788A1,1,BrCCC1OCCO1.OCCCCS>>OCCCCSCCC1OCCO1 -US20060063940A1,1,CCN(CC)CCOc1ccc(N)cc1.Cc1cccc2c1C(=CO)C(=O)N2>>CCN(CC)CCOc1ccc(NC=C2C(=O)Nc3cccc(C)c32)cc1 -US20150210657A1,7,c1ccc(C2=Nc3ccccc3OC2)cc1>>c1ccc([C@@H]2COc3ccccc3N2)cc1 -US20100120740A1,2,CN1CCNCC1.O=C(O)c1cc2occc2[nH]1>>CN1CCN(C(=O)c2cc3occc3[nH]2)CC1 -US20130231319A1,1,F[C@H]1CCNC1.OCCOCCCl>>OCCOCCN1CC[C@H](F)C1 -US07208494B2,6,CCOC(=O)c1cc2cc(OCC)c(Cl)nc2n1C(=O)OC(C)(C)C>>CCOC(=O)c1cc2cc(OCC)c(Cl)nc2[nH]1 -US20050261285A1,1,Brc1cccnc1.C[C@@H](O[C@H]1OCC[C@@H](CN2CCNCC2=O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1OCC[C@@H](CN2CCN(c3cccnc3)CC2=O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US06806265B2,4,Cc1cc(C(=O)CBr)ccc1O.NC(N)=S>>Cc1cc(-c2csc(N)n2)ccc1O -US07226927B2,1,COc1ccc(OC)c(N)c1.FC(F)(F)c1cc(Cl)nc(-c2ccncc2)n1>>COc1ccc(OC)c(Nc2cc(C(F)(F)F)nc(-c3ccncc3)n2)c1 -US20110105436A1,4,NC(=S)Nc1cccc(O)c1.O=C(CBr)c1ccncc1>>Oc1cccc(Nc2nc(-c3ccncc3)cs2)c1 -US05312950,2,C=CC(O)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>C=CC(O)COS(=O)(=O)c1ccc(C)cc1 -US20130303497A1,6,CCOC(=O)CCCNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCC(=O)O -US04387230,7,Cc1ccc(C2=CC(O)CN(C)C2)cc1>>Cc1ccc([C@@H]2C[C@H](O)CN(C)C2)cc1 -US20080153871A1,2,CC(C)(C)c1ccccc1N.O=C(Cl)CCBr>>CC(C)(C)c1ccccc1NC(=O)CCBr -US06083943,1,COC(=O)[C@H]1[C@H](N)[C@H](c2ccccc2)N(C(=O)OCc2ccccc2)[C@@H]1C.COc1ccc(OC(F)(F)F)cc1C=O>>COC(=O)[C@@H]1[C@H](NCc2cc(OC(F)(F)F)ccc2OC)[C@H](c2ccccc2)N(C(=O)OCc2ccccc2)[C@@H]1C -US04237298,6,COC(=O)C(SC)c1ccc(N(C)C)cc1>>CSC(C(=O)O)c1ccc(N(C)C)cc1 -US20140249139A1,3,Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(=O)O.Clc1ncnc2ccc(Br)cc12>>Cc1ccc(-c2ncnc3ccc(Br)cc23)cc1C(=O)O -US20150232469A1,6,CC1CN(c2nc3ccccc3nc2NC2CC2)CCN1C(=O)OC(C)(C)C>>CC1CN(c2nc3ccccc3nc2NC2CC2)CCN1 -US08124299B2,3,C#Cc1cc(OC)cc(OC)c1.C[Si](C)(C)C#Cc1ccc(I)cc1>>COc1cc(C#Cc2ccc(C#C[Si](C)(C)C)cc2)cc(OC)c1 -US05565485,7,C=CCc1cc(C#N)ccc1O>>CCCc1cc(C#N)ccc1O -US20060178410A1,7,N#CCc1ccc(I)cc1>>NCCc1ccc(I)cc1 -US07550478B2,3,CN(CC1COCCO1)S(=O)(=O)Nc1ccc2ccc3ncc(Cl)cc3c(=O)c2c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 -US04728646,1,O=CN1CCNCC1.Sc1ncnc2c(N3CCOCC3)nc(Cl)nc12>>O=CN1CCN(c2nc(N3CCOCC3)c3ncnc(S)c3n2)CC1 -US07879843B2,6,CCOC(=O)c1ccc2c(c1)N(CC(=O)NO)C(=O)C(CCCc1ccc(OC)cc1)S2>>COc1ccc(CCCC2Sc3ccc(C(=O)O)cc3N(CC(=O)NO)C2=O)cc1 -US07282496B2,2,C=C=CCOc1ccc(S(=O)(=O)Cl)cc1.COC(=O)[C@@H]1NCCSC1(C)C>>C=C=CCOc1ccc(S(=O)(=O)N2CCSC(C)(C)[C@@H]2C(=O)OC)cc1 -US20040019063A1,1,Cc1c(NC(=O)N2CC[C@@H](O[Si](C)(C)C(C)(C)C)[C@@]2(C)CO)ccc(C#N)c1Cl>>Cc1c(N2C[C@]3(C)[C@H](O[Si](C)(C)C(C)(C)C)CCN3C2=O)ccc(C#N)c1Cl -US06867204B2,1,CC(C)(C)OC(=O)N1CCNCC1.O=S(=O)(c1ccccc1)N1CCOc2c(Br)cc(Cl)cc21>>CC(C)(C)OC(=O)N1CCN(c2cc(Cl)cc3c2OCCN3S(=O)(=O)c2ccccc2)CC1 -US20060128695A1,3,COc1cc2c(cc1OC)N(C)C(=O)CN=C2c1cccc(Br)c1.OB(O)c1ccc(Cl)cc1>>COc1cc2c(cc1OC)N(C)C(=O)CN=C2c1cccc(-c2ccc(Cl)cc2)c1 -US08389248B2,7,C[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O>>C[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO -US04017522,2,CCCCCCCCCCCC(=O)N(C)CCO.O=C(Cl)c1ccco1>>CCCCCCCCCCCC(=O)N(C)CCOC(=O)c1ccco1 -US20040209921A1,7,N#Cc1ncccc1N1CCCCC1>>NCc1ncccc1N1CCCCC1 -US04806539,1,C(=Cc1ccccc1)CN1CCNCC1.O=C(O)c1cn(C2CC2)c2cc(Cl)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2cc(N3CCN(CC=Cc4ccccc4)CC3)c(F)cc2c1=O -US07544704B2,2,Cc1onc(-c2ccccc2)c1C#Cc1ccc(C(=O)O)cc1.NC1CCOCC1>>Cc1onc(-c2ccccc2)c1C#Cc1ccc(C(=O)NC2CCOCC2)cc1 -US20110301134A1,3,C#CCCCCC(=O)O.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)OC(C)c1ccccc1Cl>>Cc1noc(-c2ccc(C#CCCCCC(=O)O)cc2)c1NC(=O)OC(C)c1ccccc1Cl -US20100099681A1,6,COC(=O)c1cc(OC)ccc1Br>>COC(=O)c1cc(O)ccc1Br -US20130196974A1,1,Cc1ccc2nc(N3CCS(=O)c4ccccc4C3)cc(Cl)c2c1.NCCO>>Cc1ccc2nc(N3CCS(=O)c4ccccc4C3)cc(NCCO)c2c1 -US06541470B1,3,CCn1c2c(c(=O)c3cc(C(C)C)ccc31)C(=O)c1ccccc1-2.[Mg+]c1ccccc1>>CCn1c2c(c(=O)c3cc(C(C)C)ccc31)C(O)(c1ccccc1)c1ccccc1-2 -US07781431B2,6,COC(=O)c1cc2[nH]c(-c3ccccc3)c(C3CCCCC3)c2s1>>O=C(O)c1cc2[nH]c(-c3ccccc3)c(C3CCCCC3)c2s1 -US04588732,6,CCOC(=O)c1ccc(-c2cccc3cncn23)cc1>>O=C(O)c1ccc(-c2cccc3cncn23)cc1 -US20150175628A1,2,CC(=O)NCC(=O)O.COc1cc(Br)ccc1C(=O)NN>>COc1cc(Br)ccc1C(=O)NNC(=O)CNC(C)=O -US20090286778A1,2,CN=C=O.O=C(COc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2)N1CCNCC1>>CNC(=O)N1CCN(C(=O)COc2ccc3cc2CCc2cncc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US20090203737A1,8,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1CC(=O)CN1C(=O)OC(C)(C)C -US20120101083A1,2,CNC.Cc1c(-c2nnc(-c3ccc(OC(C)C)c(C#N)c3)s2)ccc2c1CCN(CCC(=O)O)C2>>Cc1c(-c2nnc(-c3ccc(OC(C)C)c(C#N)c3)s2)ccc2c1CCN(CCC(=O)N(C)C)C2 -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccc2C1=O -US20110237620A1,2,Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1F.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(Nc1cccc(C(F)(F)F)c1)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1F -US20090176804A1,3,Cc1cccc2c1cc(B(O)O)n2C(=O)OC(C)(C)C.O=S(=O)(NC1CCCCC1)c1cc(Br)ccc1Cl>>Cc1cccc2c1cc(-c1ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c1)n2C(=O)OC(C)(C)C -US20100048631A1,1,CC(C)c1nc(N2CCC(CCCO)CC2)no1.CS(=O)(=O)Cc1ccc(O)cc1F>>CC(C)c1nc(N2CCC(CCCOc3ccc(CS(C)(=O)=O)c(F)c3)CC2)no1 -US07176207B2,7,Cc1c(Cl)ccc([N+](=O)[O-])c1Cl>>Cc1c(Cl)ccc(N)c1Cl -US07833939B2,1,CCOC(=O)c1cn[nH]c1.FC(F)Cl>>CCOC(=O)c1cnn(C(F)F)c1 -US07576104B2,2,Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.O=C(Cl)CCl>>O=C1CCC(N2Cc3c(NC(=O)CCl)cccc3C2=O)C(=O)N1 -US20150126486A1,1,COC(=O)Cc1ccc(O)cc1.ClCc1ccccc1>>COC(=O)Cc1ccc(OCc2ccccc2)cc1 -US20060217424A1,1,CCOc1c(O)cccc1C=O.N#Cc1ccc(Cl)cc1F>>CCOc1c(C=O)cccc1Oc1cc(Cl)ccc1C#N -US20120264747A1,6,COC(=O)c1ccc(Nc2nc3cccc(-c4cccc(Cl)c4)n3n2)cc1>>O=C(O)c1ccc(Nc2nc3cccc(-c4cccc(Cl)c4)n3n2)cc1 -US20150065482A1,1,ClCCN1CCOCC1.NC(=O)c1nn(-c2cccc(I)c2)c2ccc(O)cc12>>NC(=O)c1nn(-c2cccc(I)c2)c2ccc(OCCN3CCOCC3)cc12 -US20020035266A1,6,COC(=O)C(CC1CCCC1)c1ccc(-n2nnnc2C)c(F)c1>>Cc1nnnn1-c1ccc(C(CC2CCCC2)C(=O)O)cc1F -US08426420B2,6,CCCCOC(=O)NC1CCN(C(=O)OCc2ccccc2)C1>>CCCCOC(=O)NC1CCNC1 -US08183413B2,6,CCC[C@H](NC(=O)OC(C)(C)C)[C@H](O)C(=O)NC1CC1>>CCC[C@H](N)[C@H](O)C(=O)NC1CC1 -US08969376B2,3,Cc1nc2ccccc2nc1-c1cc2nc(Cl)cc(NC3CCOCC3)n2n1.OB(O)C1=CCCC1>>Cc1nc2ccccc2nc1-c1cc2nc(C3=CCCC3)cc(NC3CCOCC3)n2n1 -US07973026B2,6,COC(=O)c1cc2c(s1)c(C1CCCCC1)c(Br)n2C(=O)OC(C)(C)C>>COC(=O)c1cc2[nH]c(Br)c(C3CCCCC3)c2s1 -US07994333B2,1,CC(=O)O.O=C(CCl)Cc1csc2ccccc12>>CC(=O)OCC(=O)Cc1csc2ccccc12 -US08119663B2,2,Fc1cccc(-c2noc(C3CNCC(c4ccc(OC(F)(F)F)cc4)C3)n2)c1.O=C(Cl)OC(Cl)(Cl)Cl>>O=C(Cl)N1CC(c2ccc(OC(F)(F)F)cc2)CC(c2nc(-c3cccc(F)c3)no2)C1 -US20150210722A1,1,CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2ccc(P(C)(C)=O)cc2)n1.OC[C@@H]1CCCN1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(N4CCC[C@H]4CO)n3)c3ccccc23)n(-c2ccc(P(C)(C)=O)cc2)n1 -US05972965,6,COc1cccc2c1CCC2N(Cc1nc(-c2ccccc2)c(-c2ccccc2)o1)C(=O)C(F)(F)F>>COc1cccc2c1CCC2NCc1nc(-c2ccccc2)c(-c2ccccc2)o1 -US08324396B2,1,NC1CC1.O=CCC(c1ccc(F)cc1)c1ccc(F)cc1>>Fc1ccc(C(CCNC2CC2)c2ccc(F)cc2)cc1 -US20140058098A1,9,CC(C)n1ncnc1-c1cn2c(n1)-c1cc(Cl)ncc1OCC2>>CC(C)n1ncnc1-c1cn2c(n1)-c1ccncc1OCC2 -US04382892,1,CC(=O)CCl.O=[N+]([O-])c1ccc(F)c(F)c1O>>CC(=O)COc1c([N+](=O)[O-])ccc(F)c1F -US20100105655A1,1,COc1cc(N2CCN(CCO)CC2)ccc1N.Cc1cnc(Cl)nc1-c1cnc2ccccn12>>COc1cc(N2CCN(CCO)CC2)ccc1Nc1ncc(C)c(-c2cnc3ccccn23)n1 -US20090048258A1,2,CCOc1ccc(C(=O)CCC(=O)O)cc1Cl.Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1>>CCOc1ccc(C(=O)CCC(=O)Nc2nc(-c3ccccc3)c(Cc3ccccc3)s2)cc1Cl -US05985524,2,C=C(C)C(=O)Cl.C[Si](C)(C)[Si](CCO)([Si](C)(C)C)[Si](C)(C)C>>C=C(C)C(=O)OCC[Si]([Si](C)(C)C)([Si](C)(C)C)[Si](C)(C)C -US08269002B2,1,CCOC(=O)[C@H](C)Oc1cc(Cl)nc(SCc2cccc(F)c2F)n1.NS(=O)(=O)N1CCC1>>CCOC(=O)[C@H](C)Oc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1 -US04591458,6,CCOC(=O)[C@H](CCCCCN)N[C@H]1COc2ccccc2N(CC(=O)O)C1=O>>NCCCCC[C@H](N[C@H]1COc2ccccc2N(CC(=O)O)C1=O)C(=O)O -US20140309227A1,1,NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CBr)cc2n1.c1ccc2[nH]cnc2c1>>NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(Cn3cnc4ccccc43)cc2n1 -US20110218189A1,6,CC(C)(C)OC(=O)N1CCC[C@H](Cn2c(-c3ccccc3Cl)cc3cnc(NCc4ccc(F)c(F)c4)nc32)C1>>Fc1ccc(CNc2ncc3cc(-c4ccccc4Cl)n(C[C@H]4CCCNC4)c3n2)cc1F -US20120270838A1,6,CNc1cc(C)c(CC2(S(=O)(=O)N3CCC4(CC3)OCCO4)CC2)c(C)c1>>CNc1cc(C)c(CC2(S(=O)(=O)N3CCC(=O)CC3)CC2)c(C)c1 -US06121491,7,CN(C)C(C)(Cc1ccc(Cl)c(Cl)c1)C(=O)O>>CN(C)C(C)(CO)Cc1ccc(Cl)c(Cl)c1 -US20040259843A1,1,CC1(NC(=O)OCc2ccccc2)CCNCC1.N#Cc1ccc(Cl)nc1>>CC1(NC(=O)OCc2ccccc2)CCN(c2ccc(C#N)cn2)CC1 -US08546405B2,2,CC(C)c1ccc2c(Nc3cc(N)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1.CC(C)c1ccc2c(Nc3cccc(C(=O)O)c3)ncnc2n1>>CC(C)c1ccc2c(Nc3cccc(C(=O)Nc4ccc(Sc5ccc(NC(=O)OC(C)(C)C)cc5)c(Nc5ncnc6nc(C(C)C)ccc56)c4)c3)ncnc2n1 -US06818663B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNCCOc1ccc([N+](=O)[O-])cc1>>CCN(CCOc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C -US05541195,2,O=C(N(Cc1ccnc2ccccc12)[C@H]1CCN[C@H](Cc2ccccc2)C1)C(F)(F)F.O=C(O)C(c1ccccc1)c1ccccc1>>O=C(C(c1ccccc1)c1ccccc1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1 -US05130339,7,O=C(NCC1CCc2cc(O)ccc2C1)C(O)c1ccc(Cl)cc1>>Oc1ccc2c(c1)CCC(CNCC(O)c1ccc(Cl)cc1)C2 -US08853215B2,8,CC(O)c1cc(Cl)cc(C(F)(F)F)c1>>CC(=O)c1cc(Cl)cc(C(F)(F)F)c1 -US20150148334A1,3,COC(=O)CC(=O)c1ccc(Br)s1.O=Cc1ccc(Cl)c(Cl)c1>>COC(=O)/C(=C\c1ccc(Cl)c(Cl)c1)C(=O)c1ccc(Br)s1 -US20120238750A1,7,O=C(c1ccc(Oc2ccc([N+](=O)[O-])cn2)cc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1>>Nc1ccc(Oc2ccc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)cc2)nc1 -US08586599B2,1,Cn1cc(-c2ccc(=O)n(Cc3cccc(-c4ncc(O)cn4)c3)n2)cn1.OCCN1CCOCC1>>Cn1cc(-c2ccc(=O)n(Cc3cccc(-c4ncc(OCCN5CCOCC5)cn4)c3)n2)cn1 -US05565575,3,O=C1CNC(=O)N1.O=CC1CC=CCC1>>O=C1NC(=O)C(=CC2CC=CCC2)N1 -US04908371,2,CCN(CC)C(=O)Cl.Cc1c(O)c(=O)ccn1C>>CCN(CC)C(=O)Oc1c(C)n(C)ccc1=O -US05081145,7,COc1ccc2c(c1)c(C)c(CC(C)(C)C(=O)O)n2Cc1ccc(Cl)cc1>>COc1ccc2c(c1)c(C)c(CC(C)(C)CO)n2Cc1ccc(Cl)cc1 -US20080090814A1,1,CCOC(=O)C(=NNCCC(C)C)c1cccs1.O=C(Cl)OCc1ccccc1>>CCOC(=O)C(=NN(CCC(C)C)C(=O)OCc1ccccc1)c1cccs1 -US08399491B2,2,CN(C)c1ccc(N)cn1.C[Si](C)(C)c1ccc2c(c1)cc(C(=O)O)n2Cc1cccc(F)c1>>CN(C)c1ccc(NC(=O)c2cc3cc([Si](C)(C)C)ccc3n2Cc2cccc(F)c2)cn1 -US20050137240A1,2,CS(=O)(=O)Cl.NCCCCC(=O)Nc1nc2c(s1)CCCc1ccc(F)cc1-2>>CS(=O)(=O)NCCCCC(=O)Nc1nc2c(s1)CCCc1ccc(F)cc1-2 -US07417064B2,7,COc1ccc(F)c2ccsc12>>COc1ccc(F)c2c1SCC2 -US20130216498A1,1,N#Cc1ccc(Cl)nc1.N#Cc1ccc2ncc(-c3nccc(N[C@@H]4CCCNC4)n3)n2c1>>N#Cc1ccc(N2CCC[C@@H](Nc3ccnc(-c4cnc5ccc(C#N)cn45)n3)C2)nc1 -US20120172351A1,6,COCOc1cc(C)c(-c2cccc(C(=O)OC)c2C)c(C)c1>>COC(=O)c1cccc(-c2c(C)cc(O)cc2C)c1C -US05055458,6,CCOP(=O)(COCC(COn1cnc2c(N)ncnc21)O[Si](C)(C)C(C)(C)C)OCC>>CCOP(=O)(COCC(O)COn1cnc2c(N)ncnc21)OCC -US20100331312A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C(CO)N1CCc2cc(Br)ccc2C1>>CC1(C)OB(c2ccc3c(c2)CCN(C(=O)CO)C3)OC1(C)C -US06825181B1,1,CI.Oc1cccc2cnccc12>>COc1cccc2cnccc12 -US09133119B2,1,Brc1ccc(I)cc1.CC1(C)c2ccccc2-c2ccc(Nc3ccc(-c4ccccc4)cc3)cc21>>CC1(C)c2ccccc2-c2ccc(N(c3ccc(Br)cc3)c3ccc(-c4ccccc4)cc3)cc21 -US08722746B2,1,COc1cc(Br)c(F)cc1O.Fc1cccc(F)n1>>COc1cc(Br)c(F)cc1Oc1cccc(F)n1 -US06127391,6,CNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1cccc2ccccc12)N(C)C(=O)COCC(C)(C)NC(=O)OC(C)(C)C>>CNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1cccc2ccccc12)N(C)C(=O)COCC(C)(C)N -US08580973B2,1,FC(F)CCl.O=C1CCC(=O)N1>>O=C1CCC(=O)N1CC(F)F -US07179823B1,3,CCOC(=O)CP(=O)(OCC)OCC.Cc1nn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(C)c1C=O>>CCOC(=O)/C=C/c1c(C)nn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c1C -US20130217665A1,2,CC1(C)CC(N2CCC2C(=O)[O-])CCO1.N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2)CC1>>CC1(C)CC(N2CCC2C(=O)N2C[C@H](S(=O)(=O)c3ccccc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)CCO1 -US20090163508A1,2,Fc1cccc(-c2nccc(N3CCNCC3)n2)c1F.O=C(Nc1ccc(F)nc1)OCC(Cl)(Cl)Cl>>O=C(Nc1ccc(F)nc1)N1CCN(c2ccnc(-c3cccc(F)c3F)n2)CC1 -US05164381,3,COc1ccc(-n2nc(CCC=O)cc2-c2ccc(Cl)cc2)cc1.C[Mg+]>>COc1ccc(-n2nc(CCC(C)O)cc2-c2ccc(Cl)cc2)cc1 -US20140349987A1,2,Cc1c(C(=O)O)cc(C2=NNC3(CCCCC3)C2)n1CC1CCCCC1.NC1CCOCC1>>Cc1c(C(=O)NC2CCOCC2)cc(C2=NNC3(CCCCC3)C2)n1CC1CCCCC1 -US20090270402A1,7,CC(C)c1nnc2ccc(-c3sc(C4CCC(=O)CC4)nc3-c3ccc(F)cc3F)nn12>>CC(C)c1nnc2ccc(-c3sc([C@@H]4CC[C@H](O)CC4)nc3-c3ccc(F)cc3F)nn12 -US04822787,2,CS(=O)(=O)Cl.O=C(O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1>>CS(=O)(=O)O[C@@H]1C[C@@H](C(=O)O)N(C(=O)OCc2ccccc2)C1 -US20140187533A1,6,CC(C)(C)OC(=O)N1CC(Cc2nc3c(C(F)(F)F)cc(C(F)(F)F)cc3[nH]2)C1>>FC(F)(F)c1cc(C(F)(F)F)c2nc(CC3CNC3)[nH]c2c1 -US20130345123A1,6,C=C[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)OC(C)(C)C)C(=O)N21>>C=C[C@@H]1CCC[C@@H]2SCC[C@H](N)C(=O)N21 -US20050192287A1,2,CNc1ccc(Oc2ccnc(N)c2)cc1[N+](=O)[O-].O=C(Cl)CCl>>CNc1ccc(Oc2ccnc(NC(=O)CCl)c2)cc1[N+](=O)[O-] -US04609744,4,C=CCCC(CCCC)C(=O)OC.O=C(OO)c1cccc(Cl)c1>>CCCCC(CCC1CO1)C(=O)OC -US20100160386A1,1,CCOC(=O)c1cnc(-c2ccc(Br)cc2F)cc1Cl.Oc1ccccc1Cl>>CCOC(=O)c1cnc(-c2ccc(Br)cc2F)cc1Oc1ccccc1Cl -US20090069288A1,6,CC(C)(C)[Si](C)(C)OCc1ccc(NC(=O)c2cc(-c3ccccc3)no2)cc1>>O=C(Nc1ccc(CO)cc1)c1cc(-c2ccccc2)no1 -US20130217666A1,9,COC(=O)C1CC(O)(c2ccc(Br)cc2)C1>>COC(=O)C1CC(c2ccc(Br)cc2)C1 -US20040058907A1,1,CCOC(=O)C(Br)c1ccccc1.O=C(NCC1CNCCO1)Nc1ccc(Cl)cc1>>CCOC(=O)C(c1ccccc1)N1CCOC(CNC(=O)Nc2ccc(Cl)cc2)C1 -US20040038872A1,2,C=C[C@@H]1C[C@]1(N)C(=O)OCC.COC(=O)c1cc(O[C@@H]2C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C2)c2ccc(OC)cc2n1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(C(=O)OC)nc3cc(OC)ccc23)CN1C(=O)OC(C)(C)C)C(=O)OCC -US20080146620A1,1,Cn1nnc(N)n1.O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cn1nnc(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1 -US20100249163A1,6,CC(=O)N(C)Cc1ccc(Cl)c(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(F)c(F)c2)C2CC2)c1>>CC(=O)N(C)Cc1ccc(Cl)c(CN(C(=O)C2CNCCC2(O)c2ccc(F)c(F)c2)C2CC2)c1 -US20100292266A1,1,O=Cc1cccc(O)c1.OC1CCCCC1>>O=Cc1cccc(OC2CCCCC2)c1 -US08455477B2,2,COc1cc(-c2cnn(C)c2)cn2ncc(C(=O)O)c12.Cc1nccc(N)c1C>>COc1cc(-c2cnn(C)c2)cn2ncc(C(=O)Nc3ccnc(C)c3C)c12 -US07838518B2,6,CN1CCC(N(C)C(=O)C2CN(C(=O)OC(C)(C)C)c3ccccc32)CC1>>CN1CCC(N(C)C(=O)C2CNc3ccccc32)CC1 -US20050004134A1,2,CCOC(=O)c1nc(-c2cccc(Cl)c2)c(-c2ccc(=O)n(C(C)C)n2)s1.NC1CC1>>CC(C)n1nc(-c2sc(C(=O)NC3CC3)nc2-c2cccc(Cl)c2)ccc1=O -US20140038937A1,1,COC(=O)c1cc([C@H]2CCCN2)c2oc(N3CCOCC3)cc(=O)c2c1.Fc1cccc(Br)c1>>COC(=O)c1cc([C@H]2CCCN2c2cccc(F)c2)c2oc(N3CCOCC3)cc(=O)c2c1 -US20050182101A1,2,Cc1ccc(S(=O)(=O)CCO)cc1.O=C(O)c1cccc(S(=O)(=O)Cl)c1>>Cc1ccc(S(=O)(=O)CCOC(=O)c2cccc(S(=O)(=O)Cl)c2)cc1 -US20110112158A1,2,COC(=O)c1cc(C)ccc1O.NO>>Cc1ccc(O)c(C(=O)NO)c1 -US06645968B2,2,Nc1cccnc1.O=C(NC(N=C=S)C(Cl)(Cl)Cl)c1ccc(Cl)cc1>>O=C(NC(NC(=S)Nc1cccnc1)C(Cl)(Cl)Cl)c1ccc(Cl)cc1 -US08796256B2,3,Cc1nc(CN2C(=O)CSC2=O)n[nH]1.O=Cc1ccc2c(c1)nnn2Cc1ccc(Cl)cc1C(F)(F)F>>Cc1nc(CN2C(=O)S/C(=C\c3ccc4c(c3)nnn4Cc3ccc(Cl)cc3C(F)(F)F)C2=O)n[nH]1 -US20060183755A1,8,OCCCc1ccc(-c2cnc3c(-c4ccccc4)cnn3c2)cc1>>O=CCCc1ccc(-c2cnc3c(-c4ccccc4)cnn3c2)cc1 -US09133168B2,2,Cn1c(CC(=O)O)nc(N2CCOC(CF)C2)cc1=O.Nc1ccc(F)c(Cl)c1>>Cn1c(CC(=O)Nc2ccc(F)c(Cl)c2)nc(N2CCOC(CF)C2)cc1=O -US05041462,2,CC(=O)OCC(=O)Cl.N#Cc1c(N)cccc1N1CCCCC1>>CC(=O)OCC(=O)Nc1cccc(N2CCCCC2)c1C#N -US08129376B2,2,NCC(=O)N1CCC(Oc2ccccc2Cl)CC1.O=C(O)c1cn(-c2cncc(F)c2)nn1>>O=C(NCC(=O)N1CCC(Oc2ccccc2Cl)CC1)c1cn(-c2cncc(F)c2)nn1 -US05872118,3,O=C(Cl)CCc1ccc(F)cc1F>>O=C1CCc2c(F)cc(F)cc21 -US20020028938A1,1,CSc1ccc(-c2cnn(CC(F)(F)F)c(=O)c2O)cc1.OCC1CC1>>CSc1ccc(-c2cnn(CC(F)(F)F)c(=O)c2OCC2CC2)cc1 -US20120059028A1,3,CC1(C)OB(c2ccc3c(c2Cl)CCCO3)OC1(C)C.COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3>>COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc2c(c1Cl)CCCO2)CCCC3 -US20140024650A1,7,CCOC(=O)C1=C(N[C@@H](C)c2ccccc2)CCC(F)(F)C1>>CCOC(=O)C1CC(F)(F)CCC1N[C@@H](C)c1ccccc1 -US04512988,1,CCOC(=O)CN1CCSCC(N)C1=O.O=C(N[C@@H](Cc1ccccc1)C(=O)CCl)c1ccccc1>>CCOC(=O)CN1CCSCC(NCC(=O)C(Cc2ccccc2)NC(=O)c2ccccc2)C1=O -US20040235816A1,2,CN(C)CCCN.O=C(O)c1cccc(CS(=O)(=O)C=C2CN(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)C2)c1>>CN(C)CCCNC(=O)c1cccc(CS(=O)(=O)C=C2CN(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)C2)c1 -US05977105,6,COc1ccc(-c2cccnc2)cc1>>Oc1ccc(-c2cccnc2)cc1 -US04857530,1,C#CCBr.Nc1ccc(F)cc1>>C#CCNc1ccc(F)cc1 -US20120129858A1,2,Cc1ccc(S(N)(=O)=O)cc1.O=C(O)c1ccc(-c2ccc(OCCc3ccc(Cl)cc3)nn2)cc1>>Cc1ccc(S(=O)(=O)NC(=O)c2ccc(-c3ccc(OCCc4ccc(Cl)cc4)nn3)cc2)cc1 -US08344135B2,7,O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cn2)ccc1Cl)C(F)(F)F>>Nc1ccc(Oc2ccc(Cl)c(NC(=O)C(F)(F)F)c2)nc1 -US20140329858A1,6,CCOC(=O)c1ccc(N2C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)[C@H]3CCCC[C@@H]32)cc1>>N#Cc1ccc(N2C(=O)N(c3ccc(C(=O)O)cc3)[C@H]3CCCC[C@@H]32)cc1C(F)(F)F -US05739351,2,COc1ccccc1CC(=O)O.N#CCC1CC2CNCC2C(O)(c2ccccc2)C1>>COc1ccccc1CC(=O)N1CC2CC(CC#N)CC(O)(c3ccccc3)C2C1 -US07250518B2,6,COC(=O)C(C)(C)c1ccc(CNC(=O)c2cccnc2Oc2ccc3c(c2)OCO3)cc1>>CC(C)(C(=O)O)c1ccc(CNC(=O)c2cccnc2Oc2ccc3c(c2)OCO3)cc1 -US20130253002A1,7,COC/C=C/c1cnc2c(N)nc3ccccc3c2c1>>COCCCc1cnc2c(N)nc3ccccc3c2c1 -US07491720B2,7,COC(=O)c1cc(O)cc(Nc2ccn(COCC[Si](C)(C)C)n2)n1>>C[Si](C)(C)CCOCn1ccc(Nc2cc(O)cc(CO)n2)n1 -US03997535,2,COc1nc2ccccc2nc1C(=O)O.Nc1nnn[nH]1>>COc1nc2ccccc2nc1C(=O)Nc1nnn[nH]1 -US05354769,1,CI.c1ccc2oc(-c3ncc[nH]3)cc2c1>>Cn1ccnc1-c1cc2ccccc2o1 -US05444083,7,COc1ccc(CN2CC(c3ccc(OC)c(OC)c3)C(Cc3cc(F)cc(F)c3OC)C2=O)cc1OC>>COc1ccc(CN2CC(Cc3cc(F)cc(F)c3OC)C(c3ccc(OC)c(OC)c3)C2)cc1OC -US08598355B2,4,C#Cc1cc(C#N)cc(Br)c1N>>N#Cc1cc(Br)c2[nH]ccc2c1 -US20120172599A1,3,CCCCN(CCCC)c1ccc(C=CC2=C(OC)C(=O)CC(C)(C)C2)c(OC)c1.CCOP(=O)(CC#N)OCC>>CCCCN(CCCC)c1ccc(C=CC2=C(OC)C(=CC#N)CC(C)(C)C2)c(OC)c1 -US06057319,6,CCOC(=O)COc1ccc(OC)c(Cl)c1>>COc1ccc(OCC(=O)O)cc1Cl -US20130217664A1,1,CB(O)O.CCc1cc(Br)ccc1N>>CCc1cc(Br)ccc1NC -US08809376B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C#N)c4Br)ccc21.Fc1ccc(CBr)cc1>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C#N)c4Cc3ccc(F)cc3)ccc21 -US20130190287A1,1,CC(C)Nc1nc(N)nc(-c2cccc(C(F)(F)F)n2)n1.N#CC1(c2cc(Cl)ccn2)CC1>>CC(C)Nc1nc(Nc2ccnc(C3(C#N)CC3)c2)nc(-c2cccc(C(F)(F)F)n2)n1 -US20030078251A1,8,O=[N+]([O-])c1ccc2oc(CO)cc2c1>>O=Cc1cc2cc([N+](=O)[O-])ccc2o1 -US20090118284A1,7,O=[N+]([O-])c1cnc2[nH]ncc2c1>>Nc1cnc2[nH]ncc2c1 -US20040077584A1,1,CC(C)NC1CCCCC1.N#CCO>>CC(C)N(CC#N)C1CCCCC1 -US20080312192A1,1,COc1ccc(Cl)cc1N.O=C(Nc1ccc(Oc2cc(Cl)ncn2)cc1)Nc1ccc(N2CCOCC2)c(C(F)(F)F)c1>>COc1ccc(Cl)cc1Nc1cc(Oc2ccc(NC(=O)Nc3ccc(N4CCOCC4)c(C(F)(F)F)c3)cc2)ncn1 -US20100056530A1,7,CCCC=Cc1cnc(Nc2nc(C)cs2)c(OCc2ccccc2)c1>>CCCCCc1cnc(Nc2nc(C)cs2)c(OCc2ccccc2)c1 -US20080153813A1,3,Brc1cnc2ccc(NCc3ccncc3)nn12.CCCC/C=C/B(O)O>>CCCC/C=C/c1cnc2ccc(NCc3ccncc3)nn12 -US07186749B2,4,COc1ccc2cc(C(=O)CCC(=O)c3ccccc3)ccc2c1.[NH4+]>>COc1ccc2cc(-c3ccc(-c4ccccc4)[nH]3)ccc2c1 -US04705846,2,NC1(Cc2ccccc2)CCOC1=O.O=C(Cl)OCc1ccccc1>>O=C(NC1(Cc2ccccc2)CCOC1=O)OCc1ccccc1 -US20070049593A1,6,COCC[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>COCC[C@@H]1CCCNC1 -US20150152112A1,2,CCOC(=O)Cl.Nc1ccc(-c2cnc(C3CCc4cc(-c5cc(Cl)ccc5-n5cnnn5)cc(=O)n43)[nH]2)cc1>>CCOC(=O)Nc1ccc(-c2cnc(C3CCc4cc(-c5cc(Cl)ccc5-n5cnnn5)cc(=O)n43)[nH]2)cc1 -US20130196979A1,3,C#Cc1cnc2cccnn12.Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C3CC3)c2)cc1I>>Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C3CC3)c2)cc1C#Cc1cnc2cccnn12 -US20080139558A1,1,Cc1ccc(C)c(-c2nc3ccccc3[nH]2)c1.O=c1cc(CBr)c2ccc(F)c(F)c2[nH]1>>Cc1ccc(C)c(-c2nc3ccccc3n2Cc2cc(=O)[nH]c3c(F)c(F)ccc23)c1 -US05143643,1,CCCCCCCCI.CCOC(=O)C(C)O>>CCCCCCCCOC(C)C(=O)OCC -US20040142920A1,6,CC(C)(C)OC(=O)N1CCC(C)(N2CCC(N(Cc3ccccc3)c3ccccc3)CC2)CC1>>CC(C)(C)OC(=O)N1CCC(C)(N2CCC(Nc3ccccc3)CC2)CC1 -US20080255147A1,6,O=C(OCc1ccccc1)N1CCN(c2nc(-c3ccccc3F)cs2)CC1>>Fc1ccccc1-c1csc(N2CCNCC2)n1 -US20110046134A1,2,NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1.O=C(O)c1cc(-c2ccc(O)cc2)on1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cc(-c2ccc(O)cc2)on1 -US07259166B2,2,CS(=O)(=O)c1ccc([C@@H](C[C@@H]2CCC(=O)C2)C(=O)O)cc1Cl.Nc1cnccn1>>CS(=O)(=O)c1ccc([C@@H](C[C@@H]2CCC(=O)C2)C(=O)Nc2cnccn2)cc1Cl -US04495182,6,COC(=O)Cn1ccccc1=S>>O=C(O)Cn1ccccc1=S -US06492403B1,4,Cc1sc(C(=O)OC(C)C)cc1C(N)=S.O=C(CBr)c1ccccc1>>Cc1sc(C(=O)OC(C)C)cc1-c1nc(-c2ccccc2)cs1 -US20090176996A1,1,BrCC=Cc1ccccc1.CC(C)(C)OC(=O)NS(N)(=O)=O>>CC(C)(C)OC(=O)N(CC=Cc1ccccc1)S(N)(=O)=O -US07166609B2,6,COC(=O)c1ccc(CNC(=O)c2cc(C(=O)NCc3ccc4c(c3)CCO4)ncn2)cc1>>O=C(O)c1ccc(CNC(=O)c2cc(C(=O)NCc3ccc4c(c3)CCO4)ncn2)cc1 -US20130317024A1,3,CC(C)n1c(Br)cc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1F)C2=O.COc1ncc(B(O)O)c(OC)n1>>COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2F)C3=O)c(OC)n1 -US05563142,6,O=C(OCc1ccccc1)N1CCN(c2ncccc2NC(=O)C(F)(F)F)CC1>>O=C(Nc1cccnc1N1CCNCC1)C(F)(F)F -US05476875,6,COc1cc(C(=O)c2ccnc3ccccc23)cc([N+](=O)[O-])c1O>>O=C(c1cc(O)c(O)c([N+](=O)[O-])c1)c1ccnc2ccccc12 -US20120184736A1,1,Cc1cccc(C2CC2)c1O.Oc1cc(Cl)nnc1Cl>>Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O -US20120071514A1,7,O=C(O)Cc1cncc(Br)c1>>OCCc1cncc(Br)c1 -US20080269293A1,7,Cc1cc(Oc2ncccc2[N+](=O)[O-])n(-c2ccccc2)n1>>Cc1cc(Oc2ncccc2N)n(-c2ccccc2)n1 -US20130079306A1,6,COc1cc(Cl)ccc1-c1nc(C)c(NC(=O)OC(C)(C)C)s1>>COc1cc(Cl)ccc1-c1nc(C)c(N)s1 -US20100197687A1,1,CC(C)Oc1ccc(B(O)O)cc1.CCOC(=O)c1[nH]c2ccc(-c3ccc(C(F)(F)F)cn3)cc2c1I>>CCOC(=O)c1c(I)c2cc(-c3ccc(C(F)(F)F)cn3)ccc2n1-c1ccc(OC(C)C)cc1 -US07125993B2,7,CCCn1c(=O)c(N=O)c(N)n(CC)c1=O>>CCCn1c(=O)c(N)c(N)n(CC)c1=O -US20090181942A1,7,COc1cccc(C(=O)O)c1C>>COc1cccc(CO)c1C -US20040242884A1,1,CNCC(O)c1cccc(N)c1.Cc1c(CCl)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12>>Cc1c(CN(C)CC(O)c2cccc(N)c2)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12 -US20140073623A1,7,COC(=O)c1c([N+](=O)[O-])ccc2c1cc1n2CCC1>>COC(=O)c1c([N+](=O)[O-])ccc2c1CC1CCCN21 -US20070203205A1,9,O=S(=O)(c1ccc(/C=C/c2ccc(F)cc2F)nc1)c1cccc(Br)c1.[C-]#N>>N#Cc1cccc(S(=O)(=O)c2ccc(/C=C/c3ccc(F)cc3F)nc2)c1 -US08785441B2,2,Cn1ncc(Br)c1-c1cc(N)ccc1OCCN1CCCC1.O=C=Nc1ccc(F)cc1F>>Cn1ncc(Br)c1-c1cc(NC(=O)Nc2ccc(F)cc2F)ccc1OCCN1CCCC1 -US04990505,2,CCNCC.O=C(Cl)c1ccc(I)cc1>>CCN(CC)C(=O)c1ccc(I)cc1 -US20080293749A1,6,CC(C)(C)OC(=O)Nc1cc(F)cc(Cl)c1>>Nc1cc(F)cc(Cl)c1 -US20110028469A1,2,COC(=O)c1sccc1N.O=S(=O)(Cl)c1ccccc1F>>COC(=O)c1sccc1NS(=O)(=O)c1ccccc1F -US20050261177A1,6,CCOC(=O)c1ccc(N2CCN(c3nnc(-c4ccc(OCCCCCCCOC)cc4)s3)CC2)cc1>>COCCCCCCCOc1ccc(-c2nnc(N3CCN(c4ccc(C(=O)O)cc4)CC3)s2)cc1 -US07544812B2,6,O=C(OC1CCCC1)C(Cc1ccc(OCc2ccccc2)cc1)OC1CCCC1>>O=C(OC1CCCC1)C(Cc1ccc(O)cc1)OC1CCCC1 -US08629166B2,2,Nc1ccncn1.O=C(O)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1>>O=C(Nc1ccncn1)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1 -US06245773B1,2,CCC1=C(C(=O)OCc2ccccc2)C(c2ccc(F)c(F)c2)NC(OC)=N1.COC(=O)Cl>>CCC1=C(C(=O)OCc2ccccc2)C(c2ccc(F)c(F)c2)N(C(=O)OC)C(OC)=N1 -US20060160865A1,1,CCCNCCC.CN(C(=O)Oc1ccc(NC(=O)c2ccc(CCl)cc2)cn1)c1ccccc1>>CCCN(CCC)Cc1ccc(C(=O)Nc2ccc(OC(=O)N(C)c3ccccc3)nc2)cc1 -US20110218200A1,1,BrCc1ccccc1.O=C(c1ccccc1)N1CCN(c2ccc([N+](=O)[O-])c(Nc3ccccc3)c2)CC1>>O=C(c1ccccc1)N1CCN(c2ccc([N+](=O)[O-])c(N(Cc3ccccc3)c3ccccc3)c2)CC1 -US20040102436A1,6,COCOc1cccc(CN(C)c2cnc(-c3ccccc3)c(-c3ccccc3)n2)c1>>CN(Cc1cccc(O)c1)c1cnc(-c2ccccc2)c(-c2ccccc2)n1 -US20120270203A1,7,COC(=O)c1ccc(-c2cc3cc(Cl)cc(NC4CCCC4)c3[nH]2)cc1>>OCc1ccc(-c2cc3cc(Cl)cc(NC4CCCC4)c3[nH]2)cc1 -US20050267276A1,1,C=C(C)C(=O)[O-].CO[Si](CCl)(OC)OC>>C=C(C)C(=O)OC[Si](OC)(OC)OC -US20120172333A1,2,CCOC(=O)c1c(N)cc(Cl)n1-c1ccc(CC)cc1.O=C(Cl)Cc1ccccc1>>CCOC(=O)c1c(NC(=O)Cc2ccccc2)cc(Cl)n1-c1ccc(CC)cc1 -US20080161294A1,6,CCOC(=O)[C@@H](C)NC(=O)c1cc(F)ccc1N>>C[C@@H](NC(=O)c1cc(F)ccc1N)C(=O)O -US20100075973A1,2,CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3ccc(C(=O)O)cc3OC)nc2N1C(C)C.NC1CCN(C2CCN(CC3CC3)CC2)CC1>>CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C5CCN(CC6CC6)CC5)CC4)cc3OC)nc2N1C(C)C -US20140179672A1,3,CC(=O)Cc1ccc(F)cc1.N.[C-]#N>>CC(N)(C#N)Cc1ccc(F)cc1 -US20150191495A1,1,CS(=O)(=O)OC1CC(C#N)C1.Cc1cc(C)cc(O)c1>>Cc1cc(C)cc(OC2CC(C#N)C2)c1 -US20110105436A1,4,CC(C)c1cccc(NC(N)=S)c1.O=C(CBr)c1ccncc1>>CC(C)c1cccc(Nc2nc(-c3ccncc3)cs2)c1 -US08710077B2,6,O=C(NC1(c2ccc(F)cc2)CCC2(CC1)OCCO2)OCc1ccccc1>>O=C1CCC(NC(=O)OCc2ccccc2)(c2ccc(F)cc2)CC1 -US20150225397A1,7,CC1=C2CCC[C@H](O)[C@@]2(c2cccc(F)c2)CCC1=O>>C[C@@H]1C(=O)CC[C@@]2(c3cccc(F)c3)[C@H]1CCC[C@@H]2O -US20120088746A1,2,Cc1cc([C@@H](C)N)c(F)cc1NS(C)(=O)=O.O=C(O)c1ccc2nc(C(F)(F)F)cc(NC3CCCCC3)c2c1>>Cc1cc([C@@H](C)NC(=O)c2ccc3nc(C(F)(F)F)cc(NC4CCCCC4)c3c2)c(F)cc1NS(C)(=O)=O -US08173824B2,8,C[C@H](O)[C@H]1CC[C@H]2/C(=C/Br)CCC[C@@]21C>>CC(=O)[C@H]1CC[C@H]2/C(=C/Br)CCC[C@]12C -US04990504,6,NC(=O)[C@@H]1C[C@H](C(=O)NCc2ccccc2)N1>>NC(=O)[C@@H]1C[C@H](C(N)=O)N1 -US07906546B2,3,C#C[Si](C)(C)C.Cc1nnc(C(F)(C2Cc3[nH]c4ccc(Cl)cc4c3C2)S(=O)(=O)c2cccc(Br)c2)o1>>C#Cc1cccc(S(=O)(=O)C(F)(c2nnc(C)o2)C2Cc3[nH]c4ccc(Cl)cc4c3C2)c1 -US05041453,1,CCOC(=O)c1nc2ccc(CBr)cc2o1.Oc1ccc(OCc2ccc3ccccc3n2)cc1>>CCOC(=O)c1nc2ccc(COc3ccc(OCc4ccc5ccccc5n4)cc3)cc2o1 -US20150119362A1,3,COC(=O)C(C)(C)c1ccc(CB2OC(C)(C)C(C)(C)O2)cc1.Clc1cccc(-c2cc(Cl)c3c(n2)CCC3)c1>>COC(=O)C(C)(C)c1ccc(Cc2cc(-c3cccc(Cl)c3)nc3c2CCC3)cc1 -US20060258740A1,3,CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1Br.Cc1cccc(B(O)O)c1C>>Cc1cccc(-c2ccccc2CCC(=O)N(NC(=O)c2ccccc2)C(C)C)c1C -US06358992B1,1,CC(=O)[O-].CCC(Br)c1[nH]c2cc(C(=O)OC)ccc2c1C(=O)C(C)C>>CCC(OC(C)=O)c1[nH]c2cc(C(=O)OC)ccc2c1C(=O)C(C)C -US08987286B2,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c5c(-c6ccc(C#N)cc6)cccc5nn4cc3-c3ccccc3)cc2)CCC1>>N#Cc1ccc(-c2cccc3nn4cc(-c5ccccc5)c(-c5ccc(C6(N)CCC6)cc5)nc4c23)cc1 -US20060199853A1,6,CCOC(=O)c1cc(C2CCCC2)on1>>O=C(O)c1cc(C2CCCC2)on1 -US20140163009A1,3,CCOC(=O)C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cncc(Cl)c1>>CCOC(=O)/C=C/c1cncc(Cl)c1 -US05840732,3,CCC=O.O=C1CSC(=O)N1CCCCSc1cccc2nccn12>>CCC=C1SC(=O)N(CCCCSc2cccc3nccn23)C1=O -US20110251196A1,2,CCCC(C)COc1ccc([C@@H](N)CN=[N+]=[N-])cc1.C[C@H](C(=O)O)c1ccccc1>>CCCC(C)COc1ccc([C@H](CN=[N+]=[N-])NC(=O)[C@@H](C)c2ccccc2)cc1 -US05314887,8,O=S(=O)(CCCCCl)c1ccccc1CO>>O=Cc1ccccc1S(=O)(=O)CCCCCl -US20140296225A1,1,COc1cc(CC=O)ccc1[N+](=O)[O-].O=C1CNCCN1CCc1ccc([N+](=O)[O-])cc1>>COc1cc(CCN2CCN(CCc3ccc([N+](=O)[O-])cc3)C(=O)C2)ccc1[N+](=O)[O-] -US20140135316A1,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1nnc2n1-c1ccc(Br)cc1N(c1ccc([N+](=O)[O-])nc1)C[C@H]2C>>Cc1nnc2n1-c1ccc(-c3ccc(N)nc3)cc1N(c1ccc([N+](=O)[O-])nc1)C[C@H]2C -US20150158851A1,7,COC(=O)C1(C)CCC(OC)(OC)CC1>>COC1(OC)CCC(C)(CO)CC1 -US20130281428A1,3,CC(C)(C)OC(=O)N1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.Nc1ncc(Br)cc1-c1ccc(NC(=O)c2cn(CCF)cc(-c3ccc(F)cc3)c2=O)cc1>>CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc(N)c(-c4ccc(NC(=O)c5cn(CCF)cc(-c6ccc(F)cc6)c5=O)cc4)c3)cn2)CC1 -US20100048568A1,2,Cc1cn(N)c2ccc(F)cc12.Cc1nc(-c2cccc(F)c2)ncc1C(=O)O>>Cc1nc(-c2cccc(F)c2)ncc1C(=O)Nn1cc(C)c2cc(F)ccc21 -US06420390B1,2,CS(=O)(=O)Cl.C[C@H](CO)CN1CCC(c2noc3cc(F)ccc23)CC1>>C[C@H](COS(C)(=O)=O)CN1CCC(c2noc3cc(F)ccc23)CC1 -US06583150B1,9,COc1ccc(OC)c2c(N=[N+]=[N-])ccnc12>>COc1ccc(OC)c2c(N)ccnc12 -US07709471B2,1,CN1C(=O)C2(CC2)CN(C2CCCC2)c2nc(Cl)ncc21.CN1CCC(NC(=O)c2cc(Cl)c(N)cc2F)CC1>>CN1CCC(NC(=O)c2cc(Cl)c(Nc3ncc4c(n3)N(C3CCCC3)CC3(CC3)C(=O)N4C)cc2F)CC1 -US20140073792A1,1,CC(C)(C#N)c1ncccc1Br.Oc1cnc2c(F)cccc2c1>>CC(C)(C#N)c1ncccc1Oc1cnc2c(F)cccc2c1 -US20100286120A1,6,CC(C)C(C)Oc1ccc2c(n1)OCCN(C(=O)OC(C)(C)C)C2>>CC(C)C(C)Oc1ccc2c(n1)OCCNC2 -US20100249126A1,2,O=C(O)CCCCNc1cc(N2CCOCC2)nc(Cl)n1>>O=C1CCCCN1c1cc(N2CCOCC2)nc(Cl)n1 -US20140073623A1,6,CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(nc3n2CCC3)c1C(=O)OC>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(nc3n2CCC3)c1C(=O)O -US08003785B2,2,CC(C)(C)OC(=O)N1CCC(N)CC1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(F)(F)C(=O)N2C -US20130296298A1,1,CCOC(=O)C(Br)CC.Fc1ccccc1-c1nnc2ccc(S)nn12>>CCOC(=O)C(CC)Sc1ccc2nnc(-c3ccccc3F)n2n1 -US20150152121A1,1,CCCCN(C)C(=O)C1CCc2c(sc3ncnc(Cl)c23)C1.COc1cc2[nH]c(=O)sc2cc1N>>CCCCN(C)C(=O)C1CCc2c(sc3ncnc(Nc4cc5sc(=O)[nH]c5cc4OC)c23)C1 -US07199239B2,3,COc1ccc(B(O)O)cc1.Cc1c(Cl)ncnc1Cl>>COc1ccc(-c2ncnc(Cl)c2C)cc1 -US08039450B2,6,COCOc1cc(C#N)cnc1Oc1ccc2c(c1)COB2O>>N#Cc1cnc(Oc2ccc3c(c2)COB3O)c(O)c1 -US20140303161A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4F)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3F)cc1)nn2[C@@H]1CCCNC1 -US20150175610A1,3,CC(C)CCn1ccc(-c2ccn3ncc(Br)c3n2)cc1=O.COc1ncccc1B(O)O>>COc1ncccc1-c1cnn2ccc(-c3ccn(CCC(C)C)c(=O)c3)nc12 -US20100256097A1,1,NC(=O)c1cc(-c2ccccc2F)sc1N.OCC(O)c1cccc(Br)n1>>NC(=O)c1cc(-c2ccccc2F)sc1Nc1cccc(C(O)CO)n1 -US20040259904A1,3,CN(C)C=O.COc1cc2c(cc1Br)Cc1cn[nH]c1-2>>COc1cc2c(cc1C=O)Cc1cn[nH]c1-2 -US20100120775A1,9,BrC(Br)(Br)Br.COC(=O)c1c(CO)noc1C(C)C>>COC(=O)c1c(CBr)noc1C(C)C -US06756388B1,6,COc1ccc(C(=O)c2c(-c3ccc(OC)cc3)sc3cc(OC)ccc23)cc1>>COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(O)cc2)cc1 -US20040014753A1,2,COC(=O)C1CCCC2CC=CCC(N)C(=O)N21.O=C(Cl)c1ccccc1>>COC(=O)[C@@H]1CCC[C@@H]2CC=CC[C@H](NC(=O)c3ccccc3)C(=O)N21 -US04672066,2,CCCc1c(OCC(C)CC(=O)O)ccc(C(C)=O)c1O.NCCCCc1cccnc1>>CCCc1c(OCC(C)CC(=O)NCCCCc2cccnc2)ccc(C(C)=O)c1O -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(OC(F)(F)F)cc4)cc3OC)cc2C1=O>>COc1cc(NC(=O)c2ccc(OC(F)(F)F)cc2)ccc1-c1ccc2c(c1)C(=O)N([C@H](C(=O)O)C(C)C)C2 -US20120149910A1,2,CCc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1N.Cc1cc(C(=O)Cl)ccc1C#N>>CCc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(C#N)c(C)c1 -US07229987B2,2,Nc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1.O=S(=O)(Cl)CCCl>>O=S(=O)(CCCl)Nc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1 -US20120128768A1,2,CCN(CC)CCn1ccc2cc(N)ccc21.O=S(=O)(Cl)c1ccc2ccccc2c1>>CCN(CC)CCn1ccc2cc(NS(=O)(=O)c3ccc4ccccc4c3)ccc21 -US20070082912A1,6,COC(=O)c1cc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccccc2)cc(C(F)(F)F)c1>>Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(C(=O)O)cc(C(F)(F)F)c1 -US08362023B2,6,CC(C)(C)OC(=O)NC1CCC(Nc2ncc3c(-c4ccnc(NCc5ccsc5)n4)n[nH]c3n2)CC1>>NC1CCC(Nc2ncc3c(-c4ccnc(NCc5ccsc5)n4)n[nH]c3n2)CC1 -US20110021479A1,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(=O)O)CC1.NC1CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(=O)NC2CC2)CC1 -US06432950B1,1,Cc1sc2nc(-c3cccnc3)nc(Cl)c2c1C.NCCc1ccccc1>>Cc1sc2nc(-c3cccnc3)nc(NCCc3ccccc3)c2c1C -US06211234B1,6,CCOC(=O)c1cc(-c2ccc(OCc3ccccc3)cc2OCc2ccccc2)n[nH]1>>O=C(O)c1cc(-c2ccc(OCc3ccccc3)cc2OCc2ccccc2)n[nH]1 -US20060205751A1,4,N#Cc1ccc(-c2cc3cc(Cl)c(Cl)cc3[nH]2)cc1.[N-]=[N+]=[N-]>>Clc1cc2cc(-c3ccc(-c4nnn[nH]4)cc3)[nH]c2cc1Cl -US20140371239A1,1,NS(=O)(=O)c1ccc(OCCCCl)cc1.OC(c1ccccn1)(C1CCCC1)C1CCNCC1>>NS(=O)(=O)c1ccc(OCCCN2CCC(C(O)(c3ccccn3)C3CCCC3)CC2)cc1 -US20080171743A1,6,C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccccc2)nc(-c2ccc(NC(=O)OC(C)(C)C)cc2)n1>>C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccccc2)nc(-c2ccc(N)cc2)n1 -US20060160865A1,2,CN(C(=O)Oc1ccc(N)cn1)c1ccccc1.O=C(Cl)c1cccc(Br)c1>>CN(C(=O)Oc1ccc(NC(=O)c2cccc(Br)c2)cn1)c1ccccc1 -US05395969,3,CN(C)C=O.c1ccc(N(c2ccccc2)c2cccc3ccccc23)cc1>>O=Cc1ccc(N(c2ccccc2)c2ccccc2)c2ccccc12 -US20100273771A1,1,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCCNC4)no2)cc1C#N.CCOC(=O)CCCBr>>CCOC(=O)CCCN1CCCc2cc(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)ccc2C1 -US07214674B2,7,COc1c(C=O)cc(Br)cc1[N+](=O)[O-]>>COc1c(CO)cc(Br)cc1[N+](=O)[O-] -US20080125413A1,6,O=C1NC(Cc2ccccc2)CN1C1CCN(Cc2ccccc2)CC1>>O=C1NC(Cc2ccccc2)CN1C1CCNCC1 -US20040132752A1,1,COC(CBr)OC.Nc1ccc(Oc2ccccc2)cc1>>COC(CNc1ccc(Oc2ccccc2)cc1)OC -US20040209865A1,3,C#C[Si](C)(C)C.Ic1ccc2oc(CN3CCCC3)nc2c1>>C[Si](C)(C)C#Cc1ccc2oc(CN3CCCC3)nc2c1 -US20090247567A1,2,Nc1ccncc1Cl.O=C(Cl)c1cc2c(s1)-c1ccccc1OCC2>>O=C(Nc1ccncc1Cl)c1cc2c(s1)-c1ccccc1OCC2 -US06127391,6,CNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)C1CCC(NC(=O)OC(C)(C)C)CC1>>CNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)C1CCC(N)CC1 -US20110230497A1,2,CCC(=O)Cl.O=C(CC1CCNCC1)Nc1ccc(-c2ccccc2)cc1>>CCC(=O)N1CCC(CC(=O)Nc2ccc(-c3ccccc3)cc2)CC1 -US20060264460A1,8,COc1c(C)cnc(CO)c1C>>COc1c(C)cnc(C=O)c1C -US06657052B1,7,Cc1cc(C=O)cc(C)c1OC(=O)OCc1ccccc1[N+](=O)[O-]>>Cc1cc(CO)cc(C)c1OC(=O)OCc1ccccc1[N+](=O)[O-] -US04889851,1,CI.CNc1ccc2c(c1)N(C)C(=O)N(c1ccc(Cl)cc1)S2(=O)=O>>CN(C)c1ccc2c(c1)N(C)C(=O)N(c1ccc(Cl)cc1)S2(=O)=O -US05270317,7,CCOC(=O)C1(C#N)CCCC1>>CCOC(=O)C1(CN)CCCC1 -US07163953B2,1,Fc1cc(Cl)ccc1C=Cc1nc(CCl)co1.Oc1ccc(COCCn2ccnn2)cc1>>Fc1cc(Cl)ccc1/C=C/c1nc(COc2ccc(COCCn3ccnn3)cc2)co1 -US20130090323A1,1,COc1cncc(-c2cnc(Cl)cc2N)c1.Cc1c(N2CCCC2=O)nc2cc(F)cc(F)c2c1Cl>>COc1cncc(-c2cnc(Cl)cc2Nc2c(C)c(N3CCCC3=O)nc3cc(F)cc(F)c23)c1 -US08466289B2,2,C=CCC1(S(=O)(=O)Cl)CC1.Cc1c(Nc2ccc(Br)cc2F)c(N)c2n(c1=O)CCN2C(=O)OC(C)(C)C>>C=CCC1(S(=O)(=O)Nc2c(Nc3ccc(Br)cc3F)c(C)c(=O)n3c2N(C(=O)OC(C)(C)C)CC3)CC1 -US06204278B1,2,COc1cc(N)cc(OC)c1OC.O=C(O)CCCCCBr>>COc1cc(NC(=O)CCCCCBr)cc(OC)c1OC -US20090239866A1,2,NC(=O)[C@@H]1CCCN1.O=CN(C[C@@H](CC1CCCC1)C(=O)O)OCc1ccccc1>>NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1CCCC1)CN(C=O)OCc1ccccc1 -US07179823B1,6,CCOC(=O)CCc1cn(Cc2ccc(OCc3csc(C)n3)cc2)cc1-c1ccccc1>>Cc1nc(COc2ccc(Cn3cc(CCC(=O)O)c(-c4ccccc4)c3)cc2)cs1 -US20070123512A1,2,C=C(C)C(=O)Cl.Cc1cc(N)ccc1C#N>>C=C(C)C(=O)Nc1ccc(C#N)c(C)c1 -US20120059014A1,1,CCc1noc(N2CCC([C@H](C)CCOS(C)(=O)=O)CC2)n1.Oc1cnc(Cl)nc1>>CCc1noc(N2CCC([C@H](C)CCOc3cnc(Cl)nc3)CC2)n1 -US20080039473A1,2,C1CNCCN1.O=C(O)C1CCCO1>>O=C(C1CCCO1)N1CCNCC1 -US20060173034A1,7,COc1cc2ncc(C(N)=O)c(Nc3cccc4c3CCC4=O)c2cc1OC>>COc1cc2ncc(C(N)=O)c(Nc3cccc4c3CCC4O)c2cc1OC -US20110059966A1,3,C#CCCO[Si](C)(C)C(C)(C)C.Nc1ccccc1I>>CC(C)(C)[Si](C)(C)OCCC#Cc1ccccc1N -US20020107253A1,1,O=CCCCC1CC(c2cccc([N+](=O)[O-])c2)=NO1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=[N+]([O-])c1cccc(C2=NOC(CCCCN3CCN(C(c4ccccc4)c4ccccc4)CC3)C2)c1 -US07977477B2,4,Nc1ccc(CN2CCOCC2)cc1N.O=C(O)c1n[nH]cc1NC(=O)c1c(Cl)cccc1Cl>>O=C(Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1)c1c(Cl)cccc1Cl -US20070093515A1,1,COCCOc1ccc2c(c1)CNCC2.COc1cc2ncnc(Cl)c2cc1OC>>COCCOc1ccc2c(c1)CN(c1ncnc3cc(OC)c(OC)cc13)CC2 -US05574055,3,COCC1CN(c2ccc(Br)cn2)C(=O)O1.C[Sn](C)(C)C1=CCC2(CC1)OCCO2>>COCC1CN(c2ccc(C3=CCC4(CC3)OCCO4)cn2)C(=O)O1 -US20140228405A1,1,Cc1cc([C@@H]2C[C@H]2N)ccc1NC(=O)c1ccccc1.O=CC1CC1>>Cc1cc([C@@H]2C[C@H]2NCC2CC2)ccc1NC(=O)c1ccccc1 -US20120157432A1,6,c1ccc(CN2CC3CCC(C2)C3n2cnnn2)cc1>>c1nnnn1C1C2CCC1CNC2 -US20040224959A1,7,C=CCN(C(=O)c1ccc(N2CCN(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4-c4ccccc43)CC2)nc1)C1CCCCC1>>CCCN(C(=O)c1ccc(N2CCN(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4-c4ccccc43)CC2)nc1)C1CCCCC1 -US20070259874A1,4,COc1ccc(C2=NOC(C)(C#N)C2)cc1OC1CCCC1.[N-]=[N+]=[N-]>>COc1ccc(C2=NOC(C)(c3nnn[nH]3)C2)cc1OC1CCCC1 -US20090088458A1,6,COc1cc(CNC(=O)OC(C)(C)C)c(Cl)cn1>>COc1cc(C[NH3+])c(Cl)cn1 -US07388009B2,2,CCOC(=O)c1ccc(C)c(N)c1.NN>>Cc1ccc(C(=O)NN)cc1N -US05288720,3,CCCCc1nc(=O)c2cc(C(C)=O)ccc2[nH]1.CN1CCCC1=O>>CCCCc1nc(=O)c2cc(C(C)(O)C3CCN(C)C3=O)ccc2[nH]1 -US04518597,1,Cc1cc2c(cc1O)C(C)(C)OC(=O)N2.Cc1ccc(SCCCCCl)cc1>>Cc1ccc(SCCCCOc2cc3c(cc2C)NC(=O)OC3(C)C)cc1 -US09108856B2,1,CC1CCCC(N2CCCC2)C1.CI>>CC1CCCC([N+]2(C)CCCC2)C1 -US20020188009A1,1,CCOC(=O)CCCCCCBr.Cc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>CCOC(=O)CCCCCCn1c(C)nc(-c2ccccc2)c1-c1ccccc1 -US20150018547A1,6,CCOC(=O)Cc1csc2cc(OCc3ccc(C)nc3C)ccc12>>Cc1ccc(COc2ccc3c(CC(=O)O)csc3c2)c(C)n1 -US06248740B1,1,Cc1nc2ccc(Cl)nn2n1.OCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>Cc1nc2ccc(OCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn2n1 -US20090186909A1,7,Cc1cccc(C)c1-c1cc(C=O)ccc1F>>Cc1cccc(C)c1-c1cc(CO)ccc1F -US20080108683A1,4,CC(C)(C)c1cc(C(=O)CBr)cc(C(C)(C)C)c1O.CN(CCC(N)=S)C(=O)OC(C)(C)C>>CN(CCc1nc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cs1)C(=O)OC(C)(C)C -US04579866,1,BrCc1ccccc1.COC(=O)Cc1ccc(O)c(Cl)c1>>COC(=O)Cc1ccc(OCc2ccccc2)c(Cl)c1 -US06225329B1,3,COC(=O)c1cc(Br)ccc1N.OB(O)c1ccccc1>>COC(=O)c1cc(-c2ccccc2)ccc1N -US20110319378A1,7,COC(=O)C1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(Cc2ccc(OC)cc2OC)C1=O>>COc1ccc(CN2C(=O)C(C)(CO)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)c(OC)c1 -US20150232464A1,1,CI.Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(C)(CO)c1nn[nH]n1>>Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(C)(CO)c1nnn(C)n1 -US06166037,6,c1ccc(CN2CC(CN3CCC(c4ccccc4)CC3)C(c3ccccc3)C2)cc1>>c1ccc(C2CCN(CC3CNCC3c3ccccc3)CC2)cc1 -US06838453B2,6,COc1ccc2[nH]c(N[C@@H](Cc3ccc(OCCCC(=O)NC4=NCCCN4)cc3)C(=O)OC(C)(C)C)nc2c1>>COc1ccc2[nH]c(N[C@@H](Cc3ccc(OCCCC(=O)NC4=NCCCN4)cc3)C(=O)O)nc2c1 -US20020165241A1,1,Cn1cnc2ncnc(Cl)c21.NCC1CCN(S(=O)(=O)CCc2ccccc2)CC1>>Cn1cnc2ncnc(NCC3CCN(S(=O)(=O)CCc4ccccc4)CC3)c21 -US20080188528A1,6,CCOC(=O)c1cccn(-c2ccc(-c3ccccc3)cc2)c1=O>>O=C(O)c1cccn(-c2ccc(-c3ccccc3)cc2)c1=O -US20140114068A1,2,Cc1cc2c(cc1C)C1(N)C(=O)c3ccccc3C1(O)O2.O=C(O)c1cccnc1>>Cc1cc2c(cc1C)C1(NC(=O)c3cccnc3)C(=O)c3ccccc3C1(O)O2 -US20130296312A1,6,CC(C)(C)OC(=O)N1CCC(n2cc(Nc3nc4c(-c5ccc(S(C)(=O)=O)cc5)cccn4n3)cn2)CC1>>CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cnn(C5CCNCC5)c4)nc23)cc1 -US20120035214A1,7,COCCCc1ccc(Br)c(C(=O)OC)c1>>COCCCc1ccc(Br)c(CO)c1 -US20140378487A1,1,N#Cc1cc(C=O)ccc1F.Oc1cncc(C(F)(F)F)c1>>N#Cc1cc(C=O)ccc1Oc1cncc(C(F)(F)F)c1 -US03970704,10,CCOC(=O)C=C(C)/C=C/CC(C)CCC=C(C)C.O>>CCOC(=O)C=C(C)C=CCC(C)CCCC(C)(C)O -US07863293B2,1,Cc1cccnc1CN(Cc1ncccc1C)C1CCNCC1.N#CBr>>Cc1cccnc1CN(Cc1ncccc1C)C1CCN(C#N)CC1 -US20150252038A1,2,NS(=O)(=O)C1CC1.O=C(O)c1cc(C2CC2)c(CN2CCO[C@H](Cc3cc(Cl)cc(Cl)c3)C2)cc1F>>O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(CN2CCO[C@H](Cc3cc(Cl)cc(Cl)c3)C2)cc1F -US07629363B2,1,CCOC(=O)c1cnc(CBr)cn1.Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)[nH]1>>CCOC(=O)c1cnc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cn1 -US20100029657A1,6,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(-c2ccnc3c(-c4ccc(F)c5[nH]ncc45)c(-c4ccncc4)nn23)cc1>>Fc1ccc(-c2c(-c3ccncc3)nn3c(-c4ccc(N5CC6CC5CN6)cc4)ccnc23)c2cn[nH]c12 -US06380218B1,8,O=C(NCc1ccc(C(O)C(F)(F)F)cc1)c1cccnc1Oc1cccnc1>>O=C(NCc1ccc(C(=O)C(F)(F)F)cc1)c1cccnc1Oc1cccnc1 -US20130196974A1,1,Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(Cl)c2c1.NCCN1CCS(=O)(=O)CC1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NCCN3CCS(=O)(=O)CC3)c2c1 -US06489485B2,2,Nc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1.O=C(Cl)c1cccnc1>>O=C(Nc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1)c1cccnc1 -US05688815,6,Cn1ccc(=O)c(OCc2ccccc2)c1C(O)c1ccccc1>>Cn1ccc(=O)c(O)c1C(O)c1ccccc1 -US20140275070A1,9,COC(=O)c1cc2cc(C)c(OC)cc2[nH]1.N>>COc1cc2[nH]c(C(N)=O)cc2cc1C -US20100125082A1,3,N#Cc1c(F)cccc1[Zn+].O=C(Cl)c1cccc(Br)c1>>N#Cc1c(F)cccc1C(=O)c1cccc(Br)c1 -US05403859,1,BrCc1ccc2ccccc2c1.COC(=O)c1cc(I)ccc1O>>COC(=O)c1cc(I)ccc1OCc1ccc2ccccc2c1 -US06610707B1,2,CC(=O)NN.O=C(O)[C@@H]1CCCCN1S(=O)(=O)c1ccc(F)cc1>>CC(=O)NNC(=O)[C@@H]1CCCCN1S(=O)(=O)c1ccc(F)cc1 -US20110112075A1,6,CN1CCN(C(=O)[C@H](CNC(=O)c2ccc(Cl)s2)NC(=O)OC(C)(C)C)CC1>>CN1CCN(C(=O)[C@@H](N)CNC(=O)c2ccc(Cl)s2)CC1 -US20150051270A1,7,O=C(NCCN(CC(=O)c1cc2cc(OCCOC3CCCC3)ccc2o1)Cc1ccccc1)Nc1ccc(OCc2ccccc2)cc1>>O=C(NCCN(Cc1ccccc1)CC(O)c1cc2cc(OCCOC3CCCC3)ccc2o1)Nc1ccc(OCc2ccccc2)cc1 -US05556860,7,O=C1Nc2ccccc2C(c2ccccc2)N1C1CCN(Cc2cccc([N+](=O)[O-])c2)CC1>>Nc1cccc(CN2CCC(N3C(=O)Nc4ccccc4C3c3ccccc3)CC2)c1 -US07071173B2,1,BrCc1ccccc1.CCCCCCCCCCCCCCCCC(O)C(=O)O>>CCCCCCCCCCCCCCCCC(O)C(=O)OCc1ccccc1 -US07037927B2,3,Cc1ccc(Br)nc1.OB(O)c1ccccc1>>Cc1ccc(-c2ccccc2)nc1 -US08344027B2,2,CN(C)C[C@H](N)CC(=O)OCc1ccccc1.COc1ccc(OCCCCCCCCC(=O)O)cc1>>COc1ccc(OCCCCCCCCC(=O)N[C@H](CC(=O)OCc2ccccc2)CN(C)C)cc1 -US06894061B2,3,CCC1c2cc(F)ccc2-c2cc(Br)ccc2N1S(=O)(=O)c1ccc(OC)cc1.CI>>CCC1c2cc(F)ccc2-c2cc(C)ccc2N1S(=O)(=O)c1ccc(OC)cc1 -US06143750,1,C1=COCCC1.O=C1N[C@@H](c2ccc(F)c(F)c2)[C@H](CO)O1>>O=C1N[C@@H](c2ccc(F)c(F)c2)[C@H](COC2CCCCO2)O1 -US20120252853A1,7,Cc1cc2cc(C#N)ccc2n1C(F)F>>Cc1cc2cc(CN)ccc2n1C(F)F -US20060205790A1,1,CC1(C)OCc2cc([C@@H]3CN(CCc4ccc5c(c4)O[C@H](CO)CO5)C(=O)O3)ccc2O1.ClCc1ccc(Cl)nc1Cl>>CC1(C)OCc2cc(C3CN(CCc4ccc5c(c4)O[C@H](COCc4ccc(Cl)nc4Cl)CO5)C(=O)O3)ccc2O1 -US04589910,2,CNC.O=C=Nc1ccc(Oc2ccc3sncc3c2)cc1>>CN(C)C(=O)Nc1ccc(Oc2ccc3sncc3c2)cc1 -US20060223826A1,2,CNOC.O=C(O)C1CCC(c2ccccc2)CC1>>CON(C)C(=O)C1CCC(c2ccccc2)CC1 -US04582933,2,C=CC(=O)O.CCN(CC)CC(C)(C)CN>>C=CC(=O)NCC(C)(C)CN(CC)CC -US20140249104A1,6,O=C(NC1=N[C@](CF)(c2cc(O)ccc2F)C[C@@H](C(F)(F)F)O1)c1ccccc1>>NC1=N[C@](CF)(c2cc(O)ccc2F)C[C@@H](C(F)(F)F)O1 -US20070106095A1,5,CCOC(=O)c1cc2cc(C(CC)(CC)c3ccc(OCC(=O)C(C)(C)C)c(C)c3)cc(C)c2o1.OCCO>>CCOC(=O)c1cc2cc(C(CC)(CC)c3ccc(OCC4(C(C)(C)C)OCCO4)c(C)c3)cc(C)c2o1 -US06767906B2,6,CCn1cnc2c(Nc3cccc(C(=O)OC)c3)nc(N[C@@H]3CC[C@@H](O)CC3)nc21>>CCn1cnc2c(Nc3cccc(C(=O)O)c3)nc(N[C@@H]3CC[C@@H](O)CC3)nc21 -US07666834B2,1,Cc1ccc(F)c([N+](=O)[O-])c1.c1c[nH]cn1>>Cc1ccc(-n2ccnc2)c([N+](=O)[O-])c1 -US20140343000A1,6,C=C(C)[C@@H]1CC[C@]2(NCC(=O)N(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCC(=O)N(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20110166344A1,1,CI.Cc1cc(CN2C(=O)C(C3=NS(=O)(=O)c4cc(NS(C)(=O)=O)ccc4N3)=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]32)ccc1F>>Cc1cc(CN2C(=O)C(C3=NS(=O)(=O)c4cc(N(C)S(C)(=O)=O)ccc4N3)=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]32)ccc1F -US04734430,4,CC(=O)C1C(=O)CCCC1=O.NN>>Cc1n[nH]c2c1C(=O)CCC2 -US07173043B2,1,CCNCC.Cc1sc2cc(OCCCCBr)ccc2c1-c1ccc(Br)cc1>>CCN(CC)CCCCOc1ccc2c(-c3ccc(Br)cc3)c(C)sc2c1 -US06617426B1,6,C=C(C)CC(NC(=O)OC(C)(C)C)C(=O)OCC>>C=C(C)CC(NC(=O)OC(C)(C)C)C(=O)O -US20060084640A1,3,COC(=O)c1nc(N2CCN(c3ncccc3C(F)(F)F)CC2)n(COCC[Si](C)(C)C)c1Br.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)c1nc(N2CCN(c3ncccc3C(F)(F)F)CC2)n(COCC[Si](C)(C)C)c1-c1ccc(C(F)(F)F)cc1 -US20140357858A1,2,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.S=C=Nc1ccccc1Cl>>O=C1CC(=O)N(c2ccc(NC(=S)Nc3ccccc3Cl)cc2)c2ccc3ccccc3c2N1 -US04455441,7,FCCCCCCCCC#CCCOC1CCCCO1>>FCCCCCCCC/C=C\CCOC1CCCCO1 -US20150284367A1,1,CC(C)(C#N)c1cccc(Nc2cc(Cl)nnc2C(N)=O)n1.NCCN>>CC(C)(C#N)c1cccc(Nc2cc(NCCN)nnc2C(N)=O)n1 -US20120128768A1,2,CCN(CC)CCn1ccc2cc(N)ccc21.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>CCN(CC)CCn1ccc2cc(NS(=O)(=O)c3ccc(-c4ccccc4)cc3)ccc21 -US20050176775A1,1,COC(=O)c1ccc(-n2c(C)cc(O)c(Br)c2=O)cc1.Fc1ccc(CBr)c(F)c1>>COC(=O)c1ccc(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cc1 -US08791133B2,7,O=[N+]([O-])c1ccn[nH]1>>Nc1ccn[nH]1 -US07671043B2,7,N#Cc1cccc(C(=O)O)c1>>N#Cc1cccc(CO)c1 -US04952336,6,COc1ccc(CC(C)=O)cc1>>CC(=O)Cc1ccc(O)cc1 -US07960369B2,3,CC(C)(C)OC(=O)CCc1ccc(OCc2cccc(Br)c2)cc1.O=Cc1ccccc1B(O)O>>CC(C)(C)OC(=O)CCc1ccc(OCc2cccc(-c3ccccc3C=O)c2)cc1 -US20100240644A1,6,COCCCOc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CCO2)C2CC2)ccc1OC>>COCCCOc1cc(CN(C(=O)[C@H]2CNCCO2)C2CC2)ccc1OC -US20060205774A1,2,CC(C)N1CCC(Oc2ccc(C3CCNCC3)cc2)CC1.N#Cc1ccc(C(=O)O)cc1>>CC(C)N1CCC(Oc2ccc(C3CCN(C(=O)c4ccc(C#N)cc4)CC3)cc2)CC1 -US20060025400A1,6,CC(=O)OCc1cc2c(cc1[N+](=O)[O-])[C@H](NC(=O)C(F)(F)F)CCC2>>O=C(N[C@@H]1CCCc2cc(CO)c([N+](=O)[O-])cc21)C(F)(F)F -US20090270412A1,2,C1CCNCC1.Cc1ccc2c(c1)c1c(n2CCC(=O)O)CN(C)CC1>>Cc1ccc2c(c1)c1c(n2CCC(=O)N2CCCCC2)CN(C)CC1 -US09102591B2,2,Cc1ncc(C(CN)OC(C)C)cn1.O=C(O)c1cccc(Cl)c1Cl>>Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)OC(C)C)cn1 -US06194396B1,6,CCN(C(=O)OC(C)(C)C)c1cccc(OCc2ccccc2)c1[N+](=O)[O-]>>CCNc1cccc(OCc2ccccc2)c1[N+](=O)[O-] -US05607926,7,O=[N+]([O-])c1cccnc1-n1cccn1>>Nc1cccnc1-n1cccn1 -US05650422,1,C=CCBr.CCOc1ccc(O)c2c1C(=O)N(Cc1ccccc1)S2(=O)=O>>C=CCOc1ccc(OCC)c2c1S(=O)(=O)N(Cc1ccccc1)C2=O -US20090181942A1,2,C1COCCN1.COc1c(OC(F)(F)F)cccc1C(=O)O>>COc1c(OC(F)(F)F)cccc1C(=O)N1CCOCC1 -US05556977,1,COC(=O)C(C)(C)Oc1ccc(C(=O)CBr)cc1.c1cc(N2CCNCC2)ccn1>>COC(=O)C(C)(C)Oc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1 -US07348017B2,2,Nc1nc(=S)ss1.O=C(O)Cc1cc(OCc2ccc(F)cc2)cc(OCc2ccc(F)cc2)c1>>O=C(Cc1cc(OCc2ccc(F)cc2)cc(OCc2ccc(F)cc2)c1)Nc1nc(=S)ss1 -US06630461B2,7,CC(C)(C)c1cc(C(=O)NCCc2ccc([N+](=O)[O-])cc2)cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(C(=O)NCCc2ccc(N)cc2)cc(C(C)(C)C)c1O -US20060223801A1,8,COC(=O)c1cc(Cl)nc(SC)c1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1cc(Cl)nc(S(C)=O)c1 -US20080312286A1,9,CC1(C2CCCC2)Cc2cc(O)c(Cl)c(Cl)c2C1=O>>CC1(C2CCCC2)Cc2cc(O)c(Cl)cc2C1=O -US07001887B2,6,CCCS(=O)(=O)N[C@@H](C(=O)N[C@@H](CN(C)C(=O)OC(C)(C)C)C(=O)NCc1ccc(C#N)cc1)[C@H](C)CC>>CCCS(=O)(=O)N[C@@H](C(=O)N[C@@H](CNC)C(=O)NCc1ccc(C#N)cc1)[C@H](C)CC -US07045544B2,6,CC(C)(C)OC(=O)Nc1ccc(NC(=O)c2cc3cc(NC(=O)CC4CCOCC4)ccc3n2Cc2ccccc2F)cc1>>Nc1ccc(NC(=O)c2cc3cc(NC(=O)CC4CCOCC4)ccc3n2Cc2ccccc2F)cc1 -US20100179211A1,6,OC1(c2ccc(F)c(F)c2)CCN(Cc2ccccc2)C1>>OC1(c2ccc(F)c(F)c2)CCNC1 -US20110065706A1,9,CC(C)(C)OC(=O)N1CCN(c2ncc(OCc3cnc(Cl)nc3)cn2)CC1.N>>CC(C)(C)OC(=O)N1CCN(c2ncc(OCc3cnc(N)nc3)cn2)CC1 -US20070021473A1,6,CCOC(=O)c1ccc(-c2ccc(OCCCNC3CC3)c(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c2)cc1>>CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCNC3CC3)ccc21 -US05556867,3,CC(C)(C)c1ccc(OCC=O)cc1.N.[C-]#N>>CC(C)(C)c1ccc(OCC(N)C#N)cc1 -US05290785,3,Cc1c(C=O)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1c2n(c3ccccc13)C(=O)CCC2>>Cc1c2n(c3ccccc13)C(=O)C(C(O)c1ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c1C)CC2 -US06642226B2,1,BrCc1ccccc1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCNCC2)[C@H](c2ccccc2)C1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCN(Cc3ccccc3)CC2)[C@H](c2ccccc2)C1 -US04189598,2,CS(=O)(=O)Cl.N#CC(O)c1cccc(Oc2ccccc2)c1>>CS(=O)(=O)OC(C#N)c1cccc(Oc2ccccc2)c1 -US08273760B2,1,Clc1nc2ccccc2c2[nH]c3ccccc3c12.NCCNCCO>>OCCNCCNc1nc2ccccc2c2[nH]c3ccccc3c12 -US20120289522A1,1,CC(=O)CCc1c(F)cccc1Cl.Cc1noc(-c2ccc(Br)cc2)c1N>>Cc1noc(-c2ccc(Br)cc2)c1NC(C)CCc1c(F)cccc1Cl -US20070232591A1,7,COc1ccc2c(c1)CCN(S(=O)(=O)c1ccc(C)cc1)CC2=O>>COc1ccc2c(c1)CCN(S(=O)(=O)c1ccc(C)cc1)CC2 -US05880147,8,CCCCCC(CC(=O)Nc1cc(CO)ccc1C(C)(C)C)c1ccccc1C(F)(F)F>>CCCCCC(CC(=O)Nc1cc(C=O)ccc1C(C)(C)C)c1ccccc1C(F)(F)F -US08546427B2,1,CC(C)(N)C(=O)O.CC1(C)CC(c2ccccc2Br)Nc2ccc(Cl)cc21>>CC(C)(Nc1ccccc1C1CC(C)(C)c2cc(Cl)ccc2N1)C(=O)O -US20020128262A1,3,CCOP(=O)(C=C1NCCN(C)c2cc(Cl)ccc21)OCC.OB(O)c1ccccc1>>CCOP(=O)(C=C1NCCN(C)c2cc(-c3ccccc3)ccc21)OCC -US20090253750A1,3,C[C@@H]1C[C@H]1C(=O)Nc1snc(Br)c1Br.Cn1cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2n1>>C[C@@H]1C[C@H]1C(=O)Nc1snc(-c2ccc3nn(C)cc3c2)c1Br -US07649093B2,1,CCCCc1cc2cc(OC)ccc2c(O)c1-c1ccccc1.O=Cc1ccc(F)cc1>>CCCCc1cc2cc(OC)ccc2c(Oc2ccc(C=O)cc2)c1-c1ccccc1 -US07115664B2,6,CC(C)(C)OC(=O)N[C@H](C(=O)N[C@@H]1CCN(Cc2ccccc2)C1)C(C)(C)C>>CC(C)(C)[C@H](N)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 -US06143779,3,O=C1COc2cc(O)ccc21.O=Cc1cccc(Oc2ccccc2)c1>>O=C1C(=Cc2cccc(Oc3ccccc3)c2)Oc2cc(O)ccc21 -US20090069282A1,3,C#CCCc1ccc(CN2CCCC2)cc1.N#Cc1cc(-c2ccc(Cl)cc2)cnc1Cl>>N#Cc1cc(-c2ccc(Cl)cc2)cnc1C#CCCc1ccc(CN2CCCC2)cc1 -US09062055B2,1,CON(C)C(=O)c1cc2c(Cl)cccc2[nH]1.OB(O)c1cccc(F)c1>>CON(C)C(=O)c1cc2c(Cl)cccc2n1-c1cccc(F)c1 -US20130116396A1,3,C=CC(=O)OC(C)(C)C.Oc1ccc(Br)cc1>>CC(C)(C)OC(=O)C=Cc1ccc(O)cc1 -US20060189625A1,6,COc1cc(F)c(N2CCN(CCC(=O)c3ccccc3)CC2)cc1F>>O=C(CCN1CCN(c2cc(F)c(O)cc2F)CC1)c1ccccc1 -US20090149456A1,2,CN1CCC(N(C)CCOc2cc(Nc3nccc(-c4c(-c5cccc(N)c5)nn5ccccc45)n3)ccc2Cl)C1.O=C(Cl)Cc1cccs1>>CN1CCC(N(C)CCOc2cc(Nc3nccc(-c4c(-c5cccc(NC(=O)Cc6cccs6)c5)nn5ccccc45)n3)ccc2Cl)C1 -US20100210630A1,1,ClCCBr.Oc1ccc(Cc2ccccc2)cc1>>ClCCOc1ccc(Cc2ccccc2)cc1 -US04970207,2,NC1N=C(c2ccccc2)c2ccccc2N(CCOC2CCCCO2)C1=O.O=C(O)c1cc2ccccc2[nH]1>>O=C(NC1N=C(c2ccccc2)c2ccccc2N(CCOC2CCCCO2)C1=O)c1cc2ccccc2[nH]1 -US04100294,7,O=C(c1cccs1)c1cc2c(c(Cl)c1Cl)OC(C(=O)O)C2>>O=C(O)C1Cc2cc(C(O)c3cccs3)c(Cl)c(Cl)c2O1 -US06410562B1,1,BrCc1ccccc1.Clc1ccc2[nH]ccc2c1>>Clc1ccc2c(ccn2Cc2ccccc2)c1 -US20030220335A1,4,COc1cccc(CCNC=O)c1>>COc1ccc2c(c1)CCN=C2 -US20120129811A1,7,COc1c([N+](=O)[O-])cc(C(N)=O)cc1C(F)(F)F>>COc1c(N)cc(C(N)=O)cc1C(F)(F)F -US05523457,6,COC(=O)c1ccc2cccc(Br)c2c1>>O=C(O)c1ccc2cccc(Br)c2c1 -US20130261133A1,2,C=C[C@@H](C#CC#C[C@H](N)CCCCCCCCC)OC(C)=O.O=C(Cl)c1ccc(F)cc1>>C=C[C@@H](C#CC#C[C@@H](CCCCCCCCC)NC(=O)c1ccc(F)cc1)OC(C)=O -US05863903,6,OC[C@H]1CNC[C@@H](OCc2ccccc2)[C@@H]1O>>OC[C@H]1CNC[C@@H](O)[C@@H]1O -US09018214B2,1,C[C@@H]1CN[C@@H](CN2CCCC2=O)CN1C(=O)OC(C)(C)C.O=C(CBr)OCc1ccccc1>>C[C@@H]1CN(CC(=O)OCc2ccccc2)[C@@H](CN2CCCC2=O)CN1C(=O)OC(C)(C)C -US20130005707A1,8,CCC(O)c1ccc(Br)cc1F>>CCC(=O)c1ccc(Br)cc1F -US20040127706A1,6,COC(=O)[C@H](Cc1ccc(-c2c(C)ccn(C)c2=O)cc1)NC(=O)c1c(C)cccc1Cl>>Cc1cccc(Cl)c1C(=O)N[C@@H](Cc1ccc(-c2c(C)ccn(C)c2=O)cc1)C(=O)O -US07125614B2,1,Brc1ccc2c3cccc4cc5ccccc5c(c5cccc1c25)c43.Cc1ccc(Nc2ccc(C)cc2)cc1>>Cc1ccc(N(c2ccc(C)cc2)c2ccc3c4cccc5cc6ccccc6c(c6cccc2c36)c54)cc1 -US20070270385A1,6,CC(C)(C)OC(=O)NC[C@@H](O)CP(=O)(CC1CCCCC1)OC1OC(=O)c2ccccc21>>NC[C@@H](O)CP(=O)(CC1CCCCC1)OC1OC(=O)c2ccccc21 -US20100298530A1,3,C#C[Si](C)(C)C.O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1/C=C/Br>>C[Si](C)(C)C#C/C=C/c1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O -US07776924B2,2,NCCO.O=C(O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Cl>>O=C(NCCO)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Cl -US08022062B2,3,C#CC1CCCCC1.N#Cc1ccc(Cl)nc1>>N#Cc1ccc(C#CC2CCCCC2)nc1 -US04138579,1,C#CCBr.COc1cc(C(=O)O)cc(OC)c1O>>C#CCOC(=O)c1cc(OC)c(O)c(OC)c1 -US20090306197A1,7,CC(C)c1cc2c(c(-c3ccc(F)cc3)c1C(O)c1ccc(C(F)(F)F)cc1)C(=O)CC(C)(C)O2>>CC(C)c1cc2c(c(-c3ccc(F)cc3)c1[C@H](O)c1ccc(C(F)(F)F)cc1)[C@@H](O)CC(C)(C)O2 -US20130303507A1,1,Clc1cncc(Cl)n1.N#CC1(CO)CCOCC1>>N#CC1(COc2cncc(Cl)n2)CCOCC1 -US20150057272A1,2,CC(C)(C)OC(=O)Nc1ccc(CO)nc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)Nc1ccc(COS(C)(=O)=O)nc1 -US06048880,7,Cc1c(-c2ccncc2)sc(-c2ccncc2)c1C=O>>Cc1c(-c2ccncc2)sc(-c2ccncc2)c1CO -US20150119390A1,1,CN(C)C(=O)c1ccc(-c2cccc(CO)n2)cc1.COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2cccc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US06211199B1,6,CCOC(=O)Cn1c(NC2CCN(C(=O)OC(C)(C)C)CC2)nc2ccccc21>>CCOC(=O)Cn1c(NC2CCNCC2)nc2ccccc21 -US07893058B2,1,CC(C)(C)OC(=O)N(c1ccc(N2CCOCC2)cc1)c1ncc(Br)n2ccnc12.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1cnc(N(C(=O)OC(C)(C)C)c2ccc(N3CCOCC3)cc2)c2nccn12 -US20050234238A1,8,COc1ccc(C(O)c2ccc(Br)cn2)cc1>>COc1ccc(C(=O)c2ccc(Br)cn2)cc1 -US06703506B2,7,CC(=O)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O>>CC(O)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O -US20080255152A1,1,N#Cc1ccc(Oc2ccc(C=O)cc2Cl)nc1.c1ccc(C2CCNC2)cc1>>N#Cc1ccc(Oc2ccc(CN3CCC(c4ccccc4)C3)cc2Cl)nc1 -US06949648B2,9,N.O=C(O)Cc1nn(-c2ccccn2)c2[nH]c3ccccc3c(=O)c12>>NC(=O)Cc1nn(-c2ccccn2)c2[nH]c3ccccc3c(=O)c12 -US08436002B2,1,C1CNC1.CS(=O)(=O)OCCn1cc(CC(F)(F)F)nc1C1CCN(c2ncnc3c2[C@H](C(F)(F)F)CC(=O)N3)CC1>>O=C1C[C@@H](C(F)(F)F)c2c(ncnc2N2CCC(c3nc(CC(F)(F)F)cn3CCN3CCC3)CC2)N1 -US08008491B2,1,C1CNCCN1.O=Cc1c(Cl)n(-c2ccc(-c3ccccc3)cc2)c2ccccc12>>O=Cc1c(N2CCNCC2)n(-c2ccc(-c3ccccc3)cc2)c2ccccc12 -US20100179143A1,3,CC1(C)OB(c2cncc(S(=O)(=O)Nc3ccc(F)cc3F)c2)OC1(C)C.O=S(=O)(Oc1ccc2nccc(Cl)c2n1)C(F)(F)F>>O=S(=O)(Nc1ccc(F)cc1F)c1cncc(-c2ccc3nccc(Cl)c3n2)c1 -US05102891,1,Cc1cn(N)c2ccc(OCc3ccccc3)cc12.Clc1ccncc1>>Cc1cn(Nc2ccncc2)c2ccc(OCc3ccccc3)cc12 -US08119661B2,2,CC1(N2CCC(N3C(=O)N[C@H]4CCCC[C@@H]43)CC2)CCNC1.O=C(Cl)OCCF>>CC1(N2CCC(N3C(=O)N[C@H]4CCCC[C@@H]43)CC2)CCN(C(=O)OCCF)C1 -US07396840B2,3,CN(C)C=O.C[Si](C)(C)CCOCn1cnc(-c2ccc([N+](=O)[O-])cc2)c1>>C[Si](C)(C)CCOCn1cc(-c2ccc([N+](=O)[O-])cc2)nc1C=O -US08546402B2,1,COc1cc2occ(CCCCBr)c(=O)c2cc1OC.Oc1cccc(N2CCNCC2)c1>>COc1cc2occ(CCCCN3CCN(c4cccc(O)c4)CC3)c(=O)c2cc1OC -US20150272934A1,1,CC(C)(C)OC(=O)NN.CC=O>>C/C=N/NC(=O)OC(C)(C)C -US20130090323A1,3,CC1(C)OB(C2=CCOCC2)OC1(C)C.COc1cncc(-c2cnc(Cl)cc2N)c1>>COc1cncc(-c2cnc(C3=CCOCC3)cc2N)c1 -US08299057B2,2,CN1CCN(c2ccc(C(=O)O)c([N+](=O)[O-])c2)CC1.Nc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(C(=O)c3cc(F)cc(F)c3)cc12>>CN1CCN(c2ccc(C(=O)Nc3nn(C(c4ccccc4)(c4ccccc4)c4ccccc4)c4ccc(C(=O)c5cc(F)cc(F)c5)cc34)c([N+](=O)[O-])c2)CC1 -US20120101105A1,8,FC(F)(F)COc1cnc2c(c1)CCCC2.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1cc(OCC(F)(F)F)cc2c1CCCC2 -US07666879B2,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(NC(=O)Cc3ccc(-c4cnc5cc(-c6ccccn6)ccn45)cc3F)cc(C(F)(F)F)c2)CC1>>O=C(Cc1ccc(-c2cnc3cc(-c4ccccn4)ccn23)cc1F)Nc1cc(C(=O)N2CCNCC2)cc(C(F)(F)F)c1 -US06376488B1,8,C[C@H](c1ccccc1)N(CC(O)COc1ccccc1[N+](=O)[O-])C(=O)OCc1ccccc1>>C[C@H](c1ccccc1)N(CC(=O)COc1ccccc1[N+](=O)[O-])C(=O)OCc1ccccc1 -US20080139558A1,2,Cc1noc(C)c1C(=O)O.O=c1cc(CNc2cccc(Cl)c2)c2ccc(F)c(F)c2[nH]1>>Cc1noc(C)c1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 -US20130079303A1,3,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(Cl)n2)cc1.C[C@H](c1cnc(F)c(B(O)O)c1)N1CCN(C(=O)OC(C)(C)C)CC1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc([C@@H](C)N4CCN(C(=O)OC(C)(C)C)CC4)cnc3F)n2)cc1 -US08404848B2,7,O=[N+]([O-])c1ccc(N2CCC2)cn1>>Nc1ccc(N2CCC2)cn1 -US20150266881A1,3,COC(=O)c1ccc(/C=C/C(=O)OC(C)(C)C)cc1.C[S+](C)(C)=O>>COC(=O)c1ccc([C@@H]2C[C@H]2C(=O)OC(C)(C)C)cc1 -US20120282331A1,8,C[C@]12CCC3C(CC[C@H]4C[C@@H](O)CC[C@]34C)C1CC=C2n1cnc2ccccc21>>C[C@]12CCC3C(CC[C@H]4CC(=O)CC[C@]34C)C1CC=C2n1cnc2ccccc21 -US08735584B2,2,O=C=Nc1cccc(C(F)(F)F)c1.O=c1[nH]c2nccc(Oc3ccc4c(c3)OCCN4)c2c2ccccc12>>O=C(Nc1cccc(C(F)(F)F)c1)N1CCOc2cc(Oc3ccnc4[nH]c(=O)c5ccccc5c34)ccc21 -US20040209957A1,1,CCC(=O)Oc1ccc(N)cc1C(=O)O.Fc1c(F)c(C(F)(F)F)c(F)c(F)c1CBr>>CCC(=O)Oc1ccc(NCc2c(F)c(F)c(C(F)(F)F)c(F)c2F)cc1C(=O)O -US20130216498A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.Fc1ccc2ncc(-c3ncc(Cl)c(Cl)n3)n2c1>>CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nc(-c3cnc4ccc(F)cn34)ncc2Cl)C1 -US20140106991A1,1,CCCCCCBr.CCCCCCCCCCCCNC(=O)CCN1CCN(C)CC1>>CCCCCCCCCCCCNC(=O)CCN1CC[N+](C)(CCCCCC)CC1 -US20150218137A1,1,CC(C)(C)c1cc(N)[nH]n1.COCCOc1cccc(I)c1>>COCCOc1cccc(-n2nc(C(C)(C)C)cc2N)c1 -US20090029994A1,2,CC(=O)Cl.COC(=O)CCCCCN>>COC(=O)CCCCCNC(C)=O -US20150197509A1,3,Clc1cc(Cl)ncn1.OB(O)c1ccc(C(F)(F)F)nc1>>FC(F)(F)c1ccc(-c2cc(Cl)ncn2)cn1 -US20100113780A1,1,CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.Fc1ccc(CBr)c(F)c1>>CCCCc1nc(C)n(Cc2ccc(F)cc2F)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US04152459,2,COC1CCN([C@@H]2CCC[C@H]2N)CC1.COc1cc(C(=O)Cl)ccc1Cl>>COc1cc(C(=O)N[C@@H]2CCC[C@H]2N2CCC(OC)CC2)ccc1Cl -US05354747,2,Clc1ccc2c(c1)NCc1ccccc1S2.O=C(Cl)Cl>>O=C(Cl)N1Cc2ccccc2Sc2ccc(Cl)cc21 -US20130158075A1,6,CCOC(=O)CC1CCC(c2ncc(-c3ccc([N+](=O)[O-])cc3)s2)CC1>>O=C(O)CC1CCC(c2ncc(-c3ccc([N+](=O)[O-])cc3)s2)CC1 -US20050137243A1,7,O=[N+]([O-])c1ccc2c(cnn2CCN2CCOCC2)c1>>Nc1ccc2c(cnn2CCN2CCOCC2)c1 -US20130158075A1,6,COC(=O)C1CCC(c2ncc(-c3ccc(NC(=O)Nc4ccccc4)cc3)s2)CC1>>O=C(Nc1ccccc1)Nc1ccc(-c2cnc(C3CCC(C(=O)O)CC3)s2)cc1 -US08410107B2,2,Cc1cc(C(=O)O)n[nH]1.Nc1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1>>Cc1cc(C(=O)Nc2cnc(OCC(F)(F)F)c(-c3ccc(Cl)cc3)c2)n[nH]1 -US20040034031A1,3,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.CC1(C)OB(c2cccc(O)c2)OC1(C)C>>CC(C)(C)OC(=O)N1CC=C(c2cccc(O)c2)CC1 -US07230020B2,2,NCCc1cccs1.O=C(Cl)c1ccc(-c2ccccc2)cc1>>O=C(NCCc1cccs1)c1ccc(-c2ccccc2)cc1 -US20100113782A1,3,Nc1ccc(Br)cc1F.OB(O)c1ccc(F)cc1F>>Nc1ccc(-c2ccc(F)cc2F)cc1F -US05276150,2,CC1=C(C(=O)O)C(c2cccc([N+](=O)[O-])c2)C(c2ccccn2)=C(C)N1.CCCCCCO>>CCCCCCOC(=O)C1=C(C)NC(C)=C(c2ccccn2)C1c1cccc([N+](=O)[O-])c1 -US20050153408A1,9,COc1ccc2c(c1)C[C@@H](N=[N+]=[N-])CC2>>COc1ccc2c(c1)C[C@@H](N)CC2 -US20030166946A1,3,C=CC(=O)O.CC(C)n1c(Br)c(-c2ccc(F)cc2)c2ccccc21>>CC(C)n1c(/C=C/C(=O)O)c(-c2ccc(F)cc2)c2ccccc21 -US20120083469A1,8,CCOC(=O)C(CO)(CCCCB1OC(C)(C)C(C)(C)O1)NC(=O)OCc1ccccc1>>CCOC(=O)C(C=O)(CCCCB1OC(C)(C)C(C)(C)O1)NC(=O)OCc1ccccc1 -US20150182528A1,3,COC(=O)c1c(O)c2ccc(Br)cc2sc1=O.OB(O)c1ccc(F)cc1>>COC(=O)c1c(O)c2ccc(-c3ccc(F)cc3)cc2sc1=O -US07579474B2,1,CCC(C)I.OC1(c2cccc(C(F)(F)F)c2F)CCNCC1>>CCC(C)N1CCC(O)(c2cccc(C(F)(F)F)c2F)CC1 -US20020151587A1,7,O=C1CC2C(CC(OC(=O)c3ccccc3)C2CCC(F)COc2cccc(Cl)c2)O1>>O=C1CC2C(CC(O)C2CCC(F)COc2cccc(Cl)c2)O1 -US20090143383A1,1,CCCN(CCO)C(=O)OC(C)(C)C.COc1nc(Cl)ncc1[N+](=O)[O-]>>CCCN(CCOc1ncc([N+](=O)[O-])c(OC)n1)C(=O)OC(C)(C)C -US20090286778A1,1,Nc1cccc(CCCc2cccc(Nc3nc(Cl)ncc3Cl)c2)c1>>Clc1cnc2nc1Nc1cccc(c1)CCCc1cccc(c1)N2 -US20100197908A1,2,CC(=O)Cl.CC(C)(C)OC(=O)N1CCC[C@H](CN)C1>>CC(=O)NC[C@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20110092553A1,1,COC(=O)CBr.Nc1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(C(F)(F)F)cc2F)cc1>>COC(=O)CNc1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(C(F)(F)F)cc2F)cc1 -US05021426,2,CN1CCC(=C2c3ccccc3C=Cc3ccc(CN)cc32)CC1.COc1cc(C(=O)Cl)cc(OC)c1OC>>COc1cc(C(=O)NCc2ccc3c(c2)C(=C2CCN(C)CC2)c2ccccc2C=C3)cc(OC)c1OC -US20140228361A1,1,CN(C)C1C2CNCC21.ClCCCBr>>CN(C)C1C2CN(CCCCl)CC21 -US20060241302A1,9,NN.O=S(=O)(c1ccc(Cl)cc1)C(c1cc(F)ccc1F)c1cc(Cl)ncc1Cl>>NNc1cc(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(Cl)cc2)c(Cl)cn1 -US20150191439A1,1,ClCc1noc(-c2ccco2)n1.NC12CC3CC(CC(C3)C1)C2>>c1coc(-c2nc(CNC34CC5CC(CC(C5)C3)C4)no2)c1 -US05670691,2,CC(C)O.O=S(=O)(Cl)c1ccccc1C(F)(F)F>>CC(C)OS(=O)(=O)c1ccccc1C(F)(F)F -US03939166,1,C1CCNCC1.N#Cc1cc([N+](=O)[O-])c2nc(C(F)(F)F)[nH]c2c1Cl>>N#Cc1cc([N+](=O)[O-])c2nc(C(F)(F)F)[nH]c2c1N1CCCCC1 -US09034851B2,6,O=C(NC(c1ccccc1)c1ccccc1)c1cnc(COCc2ccccc2)nc1O>>O=C(NC(c1ccccc1)c1ccccc1)c1cnc(CO)nc1O -US20130345123A1,2,C=CC(C)(C)C(NC(=O)OC(C)(C)C)C(=O)O.C=CCNc1ccccc1>>C=CCN(C(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C=C)c1ccccc1 -US20040266826A1,2,CC(=O)OC(C)=O.C[Si](C)(C)CCOC(=O)C[C@]1(c2ccc(-c3ccc(-c4ccc(N)cc4)cc3)s2)CCCCS1(=O)=O>>CC(=O)Nc1ccc(-c2ccc(-c3ccc([C@@]4(CC(=O)OCC[Si](C)(C)C)CCCCS4(=O)=O)s3)cc2)cc1 -US20100311966A1,1,CCCN[C@@H]1CNCC[C@@H]1NC(=O)c1nc(Cl)c(CC)[nH]1.CCOC(=O)c1sc(Br)nc1C>>CCCN[C@@H]1CN(c2nc(C)c(C(=O)OCC)s2)CC[C@@H]1NC(=O)c1nc(Cl)c(CC)[nH]1 -US20150225390A1,6,COC(=O)c1cc(F)c(-c2cnco2)c(F)c1>>O=C(O)c1cc(F)c(-c2cnco2)c(F)c1 -US20090192213A1,7,CNC(=O)c1ccccc1I>>CNCc1ccccc1I -US05556864,6,CCc1ccc(CCc2ccccc2OCCC2CCCCN2C(=O)OC(C)(C)C)cc1>>CCc1ccc(CCc2ccccc2OCCC2CCCCN2)cc1 -US20080255202A1,6,CC(C)(C)OC(=O)C(C)(C)Sc1ccc(CN(Cc2ccco2)Cc2nnc(-c3ccccc3)o2)cc1>>CC(C)(Sc1ccc(CN(Cc2ccco2)Cc2nnc(-c3ccccc3)o2)cc1)C(=O)O -US07094789B2,6,CCc1cncc2cccc(O[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)c12>>CCc1cncc2cccc(O[C@@H]3CC[C@@H](N)CC3)c12 -US08895313B2,2,Cc1ccc2nc(-c3ccc(N)cc3)cn2c1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>Cc1ccc2nc(-c3ccc(NC(=O)c4ccc([N+](=O)[O-])cc4)cc3)cn2c1 -US20070244169A1,3,C=CC[Sn](CCCC)(CCCC)CCCC.N#Cc1cc(Br)ccc1F>>C=CCc1ccc(F)c(C#N)c1 -US20130040930A1,6,COc1ccc(CN2CC(C)N(c3ccc(C(=O)N4CCN(c5nc(C)c(C)cc5C)CC4)c(F)c3)C2=O)cc1>>Cc1cc(C)c(N2CCN(C(=O)c3ccc(N4C(=O)NCC4C)cc3F)CC2)nc1C -US07507841B2,1,C1CCNCC1.Cc1c(C)c2c(c(C)c1NC(=O)CC(C)(C)C)C(O)C(C)(C)O2>>Cc1c(C)c2c(c(C)c1NC(=O)CC(C)(C)C)C(N1CCCCC1)C(C)(C)O2 -US20100016259A1,6,CCOC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1>>O=C(O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 -US07145047B2,3,C#Cc1ccc(CCC)cc1.Fc1c(OC(F)(F)F)ccc2cc(Br)ccc12>>CCCc1ccc(C#Cc2ccc3c(F)c(OC(F)(F)F)ccc3c2)cc1 -US20140066622A1,3,CNc1ncnn2c(C)nc(-c3cnn(C)c3Br)c12.OB(O)c1ccc(C(F)(F)F)cc1>>CNc1ncnn2c(C)nc(-c3cnn(C)c3-c3ccc(C(F)(F)F)cc3)c12 -US07803806B2,2,Cc1cccc(Nc2nccc(-c3ccc(N)s3)n2)c1.O=C(O)c1ccccc1>>Cc1cccc(Nc2nccc(-c3ccc(NC(=O)c4ccccc4)s3)n2)c1 -US20030004172A1,2,Cn1c(=O)[nH]c(=O)c2sc(C(=O)O)cc21.NCc1ccccc1>>Cn1c(=O)[nH]c(=O)c2sc(C(=O)NCc3ccccc3)cc21 -US06518265B1,1,CCBr.O=C(O)CC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1>>CCOC(=O)CC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1 -US05496816,7,O=C(O)c1cccc2[nH]c(=S)sc12>>OCc1cccc2[nH]c(=S)sc12 -US07718653B2,1,COc1ccc(Cn2ncc3c(N)cccc32)cc1.Clc1ccnc(Cl)n1>>COc1ccc(Cn2ncc3c(Nc4ccnc(Cl)n4)cccc32)cc1 -US20150166483A1,1,COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(N)c4OC)c4ccccc34)n2)cc(OC)c1.Clc1ncccn1>>COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(Nc5ncccn5)c4OC)c4ccccc34)n2)cc(OC)c1 -US20140194469A1,1,COc1ccc(CO)cc1.N#Cc1ccnc(-n2nccc2O)c1>>COc1ccc(COc2ccnn2-c2cc(C#N)ccn2)cc1 -US20080255086A1,2,CS(=O)(=O)Cl.NC(=O)c1c(NC(=O)Cn2cc(CCO)c(C(F)(F)F)n2)sc2c1CCCC2>>CS(=O)(=O)OCCc1cn(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)nc1C(F)(F)F -US20080306144A1,2,CCC(=O)O.OCc1ccc(O)cc1>>CCC(=O)OCc1ccc(O)cc1 -US05026856,1,Brc1cccc2c1CNC2.CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23>>CC1COc2c(N3Cc4cccc(Br)c4C3)c(F)cc3c(=O)c(C(=O)O)cn1c23 -US20140163033A1,2,COC(=O)c1c(Br)ccn1N.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>COC(=O)c1c(Br)ccn1NC(=O)[C@H](C)NC(=O)OC(C)(C)C -US07105553B2,2,CNc1nc(C)c(S(N)(=O)=O)s1.O=C(O)Cc1ccc(-c2ccccc2)cc1>>Cc1nc(N(C)C(=O)Cc2ccc(-c3ccccc3)cc2)sc1S(N)(=O)=O -US20140148454A1,3,C=C(C)[Sn](CCCC)(CCCC)CCCC.COC(=O)c1ncc(N2CCOCC2)nc1Cl>>C=C(C)c1nc(N2CCOCC2)cnc1C(=O)OC -US20050080106A1,6,COCCN(C(=O)OC(C)(C)C)c1ccc(NC(=O)c2cc(OCc3ccccc3C#N)cc(OCc3ccccc3C#N)c2)nc1>>COCCNc1ccc(NC(=O)c2cc(OCc3ccccc3C#N)cc(OCc3ccccc3C#N)c2)nc1 -US20120220563A1,1,CCNCCO.O=C(N1CCOCC1)N1CC(c2ccc(C(F)(F)F)cc2)CC(c2nc(Cl)no2)C1>>CCN(CCO)c1noc(C2CC(c3ccc(C(F)(F)F)cc3)CN(C(=O)N3CCOCC3)C2)n1 -US20100041892A1,2,CC(C)OC(=O)Cl.CCCCOc1cc(CCS(N)(=O)=O)n(Cc2ccc(Cl)cc2Cl)n1>>CCCCOc1cc(CCS(=O)(=O)NC(=O)OC(C)C)n(Cc2ccc(Cl)cc2Cl)n1 -US06313310B1,3,C#Cc1ccc2c(c1)/C(=C/c1ccc[nH]1)C(=O)N2.O=[N+]([O-])c1ccc(I)cc1>>O=C1Nc2ccc(C#Cc3ccc([N+](=O)[O-])cc3)cc2/C1=C/c1ccc[nH]1 -US20110112127A1,9,Nc1ccc(C(O)c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)cn1>>Nc1ccc(Cc2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)cn1 -US20120295874A1,2,CC(C)(C)OC(=O)NCc1ccc(C(=O)NCc2ccc(OCCC(=O)O)cc2)cc1.CC1(C)O[C@@H]2CNC[C@H]2O1>>CC(C)(C)OC(=O)NCc1ccc(C(=O)NCc2ccc(OCCC(=O)N3C[C@H]4OC(C)(C)O[C@@H]4C3)cc2)cc1 -US07923559B2,1,Brc1cccnc1.c1ccc(CN2CCCC23CCNC3)cc1>>c1ccc(CN2CCCC23CCN(c2cccnc2)C3)cc1 -US20130231329A1,7,CN1CCC(OC(c2cccc(C=O)c2)c2nc3ccccc3[nH]2)CC1>>CN1CCC(OC(c2cccc(CO)c2)c2nc3ccccc3[nH]2)CC1 -US20140315881A1,8,Cc1ccc(C(NC(=O)Cc2ccc3oc(C(O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1>>Cc1ccc(C(NC(=O)Cc2ccc3oc(C(=O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1 -US08084448B2,1,FC(F)(F)c1cc[nH]n1.O=[N+]([O-])c1ccc(CBr)cc1OCc1ccccc1>>O=[N+]([O-])c1ccc(Cn2ccc(C(F)(F)F)n2)cc1OCc1ccccc1 -US04388463,2,COc1cccc2c1[C@]13CCN[C@H](C2)[C@@H]1CCC(=O)C3.O=C(O)C1CCC1>>COc1cccc2c1[C@]13CCN(C(=O)C4CCC4)[C@H](C2)[C@@H]1CCC(=O)C3 -US20080076763A1,9,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCO[C@H](CO)C1>>CC(C)(C)OC(=O)N1CCO[C@H](CBr)C1 -US20150210688A1,1,C[Si](C)(C)CCOCCl.FC(F)(F)c1c[nH]cn1>>C[Si](C)(C)CCOCn1cnc(C(F)(F)F)c1 -US07122545B2,2,COc1ccc(N2CCOCC2)cc1N.O=C(O)c1ncc[nH]1>>COc1ccc(N2CCOCC2)cc1NC(=O)c1ncc[nH]1 -US06262040B1,2,CCc1nn(C2CCCC2)c2cc(C(=O)Cl)ccc12.Nc1cccc2ncccc12>>CCc1nn(C2CCCC2)c2cc(C(=O)Nc3cccc4ncccc34)ccc12 -US03940394,1,CCOC(=O)CSc1nccc(Cl)n1.NCc1ccc(Cl)cc1>>CCOC(=O)CSc1nccc(NCc2ccc(Cl)cc2)n1 -US20130317057A1,7,O=[N+]([O-])c1ccc(F)cc1NC1CC1>>Nc1ccc(F)cc1NC1CC1 -US20110124686A1,3,CN(C)C=O.COc1ccc(Cl)cc1F>>COc1ccc(Cl)c(C=O)c1F -US07514470B2,2,CCCNCCC.CCN(CC(=O)O)c1ccc(C#N)c(C(F)(F)F)c1>>CCCN(CCC)C(=O)CN(CC)c1ccc(C#N)c(C(F)(F)F)c1 -US20090099184A1,2,NCc1ccccc1OC(F)(F)F.O=C(O)c1ccc(OCC(F)(F)F)nc1>>O=C(NCc1ccccc1OC(F)(F)F)c1ccc(OCC(F)(F)F)nc1 -US20110098286A1,1,COc1cc2ncnc(Cl)c2cc1OC.c1ccc(C2CNCCS2)cc1>>COc1cc2ncnc(N3CCSC(c4ccccc4)C3)c2cc1OC -US05223526,7,O=[N+]([O-])c1ccccc1C=C1CCCC1>>Nc1ccccc1C=C1CCCC1 -US07935721B2,3,O=C1Nc2cccc(Br)c2C12COc1cc3c(cc12)OCO3.OB(O)c1cccc2c1oc1ccccc12>>O=C1Nc2cccc(-c3cccc4c3oc3ccccc34)c2C12COc1cc3c(cc12)OCO3 -US06602872B1,1,C1COCCN1.CSc1nccc(-c2cc(OS(=O)(=O)C(F)(F)F)nnc2-c2cccc(C(F)(F)F)c2)n1>>CSc1nccc(-c2cc(N3CCOCC3)nnc2-c2cccc(C(F)(F)F)c2)n1 -US20120214803A1,7,Cc1cc([N+](=O)[O-])c(S(=O)(=O)Nc2cccc3cccnc23)cc1C>>Cc1cc(N)c(S(=O)(=O)Nc2cccc3cccnc23)cc1C -US20130109665A1,6,COC(=O)c1cnc(Br)c(-c2cccc(Cl)c2)n1>>O=C(O)c1cnc(Br)c(-c2cccc(Cl)c2)n1 -US20030083369A1,7,CCCc1cc(=O)oc2c(C(O)CC)c(O)c3c(c12)OC(C)(C)C=C3>>CCCc1cc(=O)oc2c(C(O)CC)c(O)c3c(c12)OC(C)(C)CC3 -US20140073650A1,1,CC(C)N.ClCc1nc(-c2cncnc2)no1>>CC(C)NCc1nc(-c2cncnc2)no1 -US08859545B2,6,Fc1ccc(Nc2ncnc3c2CN(Cc2ccccc2)CC3)cc1>>Fc1ccc(Nc2ncnc3c2CNCC3)cc1 -US05068340,1,CC1(C)OCC(CO)O1.COCCOCCl>>COCCOCOCC1COC(C)(C)O1 -US20100324140A1,6,CCC(Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)c1ccc(C(=O)NCCC(=O)OC)cc1>>CCC(Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 -US07056932B2,7,CCOC(C(=O)NCc1ccc(C#N)cc1[N+](=O)[O-])N1Cc2c(C)cccc2C1=O>>CCOC(C(=O)NCc1ccc(C#N)cc1N)N1Cc2c(C)cccc2C1=O -US08273750B2,1,COc1ccc(Cn2c(NN)cc(=O)n(C)c2=O)cc1.O=Cc1ccc(-c2ccccc2)cc1>>COc1ccc(Cn2c(NN=Cc3ccc(-c4ccccc4)cc3)cc(=O)n(C)c2=O)cc1 -US05405865,3,C#C[Mg+].O=Cc1ccc(C(F)(F)F)o1>>C#CC(O)c1ccc(C(F)(F)F)o1 -US20050203087A1,2,CCO.CNC(=O)N(c1cccc(-c2sc(C(=O)O)c(OCC(=O)O)c2Br)c1)C1CCCCC1>>CCOC(=O)COc1c(C(=O)O)sc(-c2cccc(N(C(=O)NC)C3CCCCC3)c2)c1Br -US20050032845A1,9,CCOC(=O)C1CC1OC1CCCCO1.N>>NC(=O)C1CC1OC1CCCCO1 -US08063048B2,7,N#Cc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1[N+](=O)[O-]>>N#Cc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1N -US20130336965A1,9,C[C@H]1C[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@@H](NC(=O)OC(C)(C)C)[C@H]1N=[N+]=[N-]>>C[C@H]1C[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@@H](NC(=O)OC(C)(C)C)[C@H]1N -US20140357858A1,2,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=C(Cl)c1c(Cl)cccc1Cl>>O=C1CC(=O)N(c2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)c2ccc3ccccc3c2N1 -US04760163,2,CCOC(=O)/C=C(/C)N.CCOC(=O)c1cc(N=C=O)ccc1Cl>>CCOC(=O)C=C(C)NC(=O)Nc1ccc(Cl)c(C(=O)OCC)c1 -US20140113005A1,2,CCC(=O)Cl.CN(Cc1ccc(-c2nnc(-c3nc(C4=CCC(N)CC4)cnc3NC(=O)OC(C)(C)C)o2)cc1)C(=O)OC(C)(C)C>>CCC(=O)NC1CC=C(c2cnc(NC(=O)OC(C)(C)C)c(-c3nnc(-c4ccc(CN(C)C(=O)OC(C)(C)C)cc4)o3)n2)CC1 -US05534516,8,CC1(C)CC(C)(C)c2cc(C#Cc3ccc(CO)cn3)ccc2O1>>CC1(C)CC(C)(C)c2cc(C#Cc3ccc(C=O)cn3)ccc2O1 -US20110112158A1,10,Cc1ccc2onc(OC3CCCCO3)c2c1.O=C1CCC(=O)N1Br>>BrCc1ccc2onc(OC3CCCCO3)c2c1 -US06399629B1,2,CC(C)(C)OC(=O)N1C[C@@H](O)C[C@H]1C(=O)Nc1ccc2c(c1)CCC2.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)O[C@H]2C[C@@H](C(=O)Nc3ccc4c(c3)CCC4)N(C(=O)OC(C)(C)C)C2)cc1 -US20150099732A1,7,Cc1cc(F)ccc1/C=C/C(=O)O>>Cc1cc(F)ccc1CCC(=O)O -US20050148627A1,6,CCOC(=O)C1=Cc2cc(Cl)c(Oc3ncc(CC)cn3)cc2OC1C(F)(F)F>>CCc1cnc(Oc2cc3c(cc2Cl)C=C(C(=O)O)C(C(F)(F)F)O3)nc1 -US20070027155A1,1,C[O-].Fc1ccc(-c2cc(N3CCN(c4ncccc4C(F)(F)F)CC3)nc(Cl)n2)cc1Cl>>COc1nc(-c2ccc(F)c(Cl)c2)cc(N2CCN(c3ncccc3C(F)(F)F)CC2)n1 -US20080287427A1,6,COC(=O)c1c[nH]c2cc(Oc3cc(N)ncn3)ccc12>>Nc1cc(Oc2ccc3c(C(=O)O)c[nH]c3c2)ncn1 -US20140350050A1,6,CC(=O)Nc1ncc(-c2cnn(C3CCN(C(=O)OC(C)(C)C)CC3)c2)cc1O[C@H](C)c1c(Cl)ccc(F)c1Cl>>CC(=O)Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1O[C@H](C)c1c(Cl)ccc(F)c1Cl -US05045541,1,CN(C)CCCCl.O=C1CC2CCc3ccc(F)cc3C2=NN1c1ccc(O)cc1>>CN(C)CCCOc1ccc(N2N=C3c4cc(F)ccc4CCC3CC2=O)cc1 -US20100063056A1,3,COc1ccc(CNC(=O)c2cc(Cl)cnc2-c2cccnc2)cc1OC.OB(O)c1cc(Cl)cc(Cl)c1>>COc1ccc(CNC(=O)c2cc(-c3cc(Cl)cc(Cl)c3)cnc2-c2cccnc2)cc1OC -US20080176830A1,7,O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2C1>>OC1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2C1 -US20130210796A1,9,Nc1cc(Br)cc(C(F)(F)F)c1.[C-]#N>>N#Cc1cc(N)cc(C(F)(F)F)c1 -US08921383B2,2,COc1ccc(Nc2nc(N3CCC(N)C3)nc3scnc23)cc1OC.O=C(O)c1ccc2[nH]ncc2c1>>COc1ccc(Nc2nc(N3CCC(NC(=O)c4ccc5[nH]ncc5c4)C3)nc3scnc23)cc1OC -US06617346B1,7,COC(=O)c1cc(Br)c(OC)cc1OC>>COc1cc(OC)c(CO)cc1Br -US08329682B2,2,CCOC(=O)c1c(CCCNCCN2CCOCC2)[nH]c(C(=O)OC(C)(C)C)c1C>>Cc1c(C(=O)OC(C)(C)C)[nH]c2c1C(=O)N(CCN1CCOCC1)CCC2 -US20030171396A1,1,COC(=O)c1ccc2nc(C)n(Cc3ccc(NC(=O)OCCCl)cc3Cl)c2n1>>COC(=O)c1ccc2nc(C)n(Cc3ccc(N4CCOC4=O)cc3Cl)c2n1 -US05089495,1,ClCc1ccc2ccccc2n1.Oc1cccc(C(O)(c2nccs2)C(F)(F)F)c1>>OC(c1cccc(OCc2ccc3ccccc3n2)c1)(c1nccs1)C(F)(F)F -US20040167123A1,1,NS(=O)(=O)c1ncccc1NC(=O)c1c(O)c2cccnc2n(Cc2ccccc2)c1=O>>O=c1c(C2=NS(=O)(=O)c3ncccc3N2)c(O)c2cccnc2n1Cc1ccccc1 -US08927536B2,3,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(Br)cc4)CC3)n2CCS1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)cn1 -US20080032972A1,2,NC1Cc2ccccc2C1.O=C(O)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1>>O=C(NC1Cc2ccccc2C1)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1 -US06319920B1,2,CC(C)(C)OC(=O)NCCC(=O)O.CCN(CC1CCNCC1)[C@@H](C)Cc1ccc2c(c1)CCO2>>CCN(CC1CCN(C(=O)CCNC(=O)OC(C)(C)C)CC1)[C@@H](C)Cc1ccc2c(c1)CCO2 -US20090227555A2,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.Cc1ccc(S(=O)(=O)N=C=O)cc1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NS(=O)(=O)c3ccc(C)cc3)CC2)nc1C(F)(F)F -US20140323463A1,1,CCc1nc(C(N)=O)c(Cl)nc1O[C@@H]1CCN(C(=O)OC(C)(C)C)C1.CN1CCN(C2CCN(c3ccc(N)cc3)CC2)CC1>>CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1O[C@@H]1CCN(C(=O)OC(C)(C)C)C1 -US08183381B2,2,CC(C)OC(=O)Cl.c1cc(-n2cnnn2)ncc1OCc1cnn(C2CCNCC2)n1>>CC(C)OC(=O)N1CCC(n2ncc(COc3ccc(-n4cnnn4)nc3)n2)CC1 -US20090181942A1,2,COC(=O)C1CNCCO1.COc1cccc([C@H]2O[C@H](CCC(=O)O)c3cccn3-c3ccc(Cl)cc32)c1OC>>COC(=O)C1CN(C(=O)CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)CCO1 -US20040044000A1,2,CS(=O)(=O)c1ccc(Cn2ccc3ccc(C(=O)O)cc3c2=O)cc1.NCc1cncnc1>>CS(=O)(=O)c1ccc(Cn2ccc3ccc(C(=O)NCc4cncnc4)cc3c2=O)cc1 -US06316487B1,1,COC(=O)CCl.O=Cc1ccccc1O>>COC(=O)COc1ccccc1C=O -US08338621B2,1,CC[C@@H](Br)C(=O)OC.COC(=O)CCCN>>CCC(NCCCC(=O)OC)C(=O)OC -US04077982,1,Fc1ccccc1CCl.O[C@@H]1CO[C@H](c2ccccc2)OC1>>Fc1ccccc1CO[C@@H]1CO[C@H](c2ccccc2)OC1 -US06713645B1,6,COC(=O)COc1cccc2c1c1c(n2Cc2ccccc2)CCCC1C(N)=O>>NC(=O)C1CCCc2c1c1c(OCC(=O)O)cccc1n2Cc1ccccc1 -US20050245592A1,1,COc1c(N)cc(C(C)=O)cc1C(C)(C)C.N#CCBr>>COc1c(NCC#N)cc(C(C)=O)cc1C(C)(C)C -US05939413,2,CC(C)(C)OC(=O)N[C@@H](CN)Cc1c[nH]c2ccccc12.O=C(Cl)CBr>>CC(C)(C)OC(=O)N[C@@H](CNC(=O)CBr)Cc1c[nH]c2ccccc12 -US20110015175A1,1,CI.O=[N+]([O-])c1cc(O)c(F)c(F)c1>>COc1cc([N+](=O)[O-])cc(F)c1F -US20100210653A1,3,C#Cc1ccccn1.COC(=O)COc1ccc(OC/C=C(\I)c2ccc(Br)cc2)cc1C>>COC(=O)COc1ccc(OC/C=C(\C#Cc2ccccn2)c2ccc(Br)cc2)cc1C -US07230023B2,2,C=CCOP(=O)(OCC=C)OCc1c(OC)cccc1C(=O)Cl.C[C@@H](S[C@H]1CO[C@H](/C=C/C=C/c2ccc(C#N)cc2F)OC1)[C@](O)(Cn1cncn1)c1ccc(F)cc1F>>C=CCOP(=O)(OCC=C)OCc1c(OC)cccc1C(=O)O[C@@](Cn1cncn1)(c1ccc(F)cc1F)[C@@H](C)S[C@H]1CO[C@H](/C=C/C=C/c2ccc(C#N)cc2F)OC1 -US07008940B1,1,C=C(C)CCl.Cc1c(O)cc2c(c1C)N(C=O)C(C)C2>>C=C(C)COc1cc2c(c(C)c1C)N(C=O)C(C)C2 -US20090275590A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CNCC2>>Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CN(C1CCN(C(=O)OC(C)(C)C)CC1)CC2 -US20050090534A1,1,O=C(O)CCc1oc(Cl)nc1-c1ccc(Cl)cc1.SC1CCCCC1>>O=C(O)CCc1oc(SC2CCCCC2)nc1-c1ccc(Cl)cc1 -US07625902B2,2,FC(F)(F)c1cnc(N2CCNCC2)c(Cl)c1.O=C(O)C1CN(S(=O)(=O)c2ccccc2C(F)(F)F)C(=O)N1c1ccccc1>>O=C(C1CN(S(=O)(=O)c2ccccc2C(F)(F)F)C(=O)N1c1ccccc1)N1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 -US20130005730A1,1,COCCCOc1cc(C[C@@H](C[C@H]2[C@H](C[C@H](C(=O)NCC(C)(C)C(N)=O)C(C)C)OCN2C(=O)OCCl)C(C)C)ccc1OC.Cc1cccnc1C(=O)O>>COCCCOc1cc(C[C@@H](C[C@H]2[C@H](C[C@H](C(=O)NCC(C)(C)C(N)=O)C(C)C)OCN2C(=O)OCOC(=O)c2ncccc2C)C(C)C)ccc1OC -US07361678B2,1,COc1ccc(O)c2ccccc12.O=[N+]([O-])c1ccc(F)cc1>>COc1ccc(Oc2ccc([N+](=O)[O-])cc2)c2ccccc12 -US07074813B2,1,NNC(=O)c1cnc(-c2ccccn2)nc1-c1ccncc1.O=Cc1cccc(C(F)(F)F)c1>>O=C(NN=Cc1cccc(C(F)(F)F)c1)c1cnc(-c2ccccn2)nc1-c1ccncc1 -US20150174110A1,2,CCOc1ncc(-c2nc(C(=O)OC)c(O)c3cc(-c4ccccc4)c(=O)n(CC4CCCCC4)c23)cn1.NCCC(=O)O>>CCOc1ncc(-c2nc(C(=O)NCCC(=O)O)c(O)c3cc(-c4ccccc4)c(=O)n(CC4CCCCC4)c23)cn1 -US07196199B2,6,COCOc1cccc2sc(-c3nnc(C)o3)cc12>>Cc1nnc(-c2cc3c(O)cccc3s2)o1 -US08697737B2,4,Nc1ccc(C2(O)c3ccccc3C(=O)N2Cc2ccccc2)cc1N.O=CO>>O=C1c2ccccc2C(O)(c2ccc3[nH]cnc3c2)N1Cc1ccccc1 -US05952368,2,CC(=O)OCCS(=O)(=O)Cl.Cn1c(Cc2ccc(N)cc2F)ccc1C(=O)c1ccccc1>>CC(=O)OCCS(=O)(=O)Nc1ccc(Cc2ccc(C(=O)c3ccccc3)n2C)c(F)c1 -US04971993,6,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CC[C@H](C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1 -US20050171181A1,9,OC1(c2ccc(CN3CCCC3)cc2)CC(COCc2ccccc2)C1>>c1ccc(COCC2CC(c3ccc(CN4CCCC4)cc3)C2)cc1 -US20020198189A1,2,COCCOC(=O)Cl.c1ccc(C2NCCc3[nH]cnc32)cc1>>COCCOC(=O)N1CCc2[nH]cnc2C1c1ccccc1 -US20030229113A1,1,O=[N+]([O-])c1ccc(Br)cc1.Oc1ccccc1>>O=[N+]([O-])c1ccc(Oc2ccccc2)cc1 -US07732618B2,1,CCCc1nc2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C.Fc1cccc(CBr)c1>>CCCc1nc2cc(N(Cc3cccc(F)c3)S(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C -US07553969B1,6,CC(C)C(NCC(Cc1ccc(F)cc1)NC(=O)OC(C)(C)C)C(=O)NC(Cc1ccc(O)c(C(C)(C)C)c1)c1nccs1>>CC(C)C(NCC(N)Cc1ccc(F)cc1)C(=O)NC(Cc1ccc(O)c(C(C)(C)C)c1)c1nccs1 -US05859032,2,CC(C)Cc1cc(C(=O)O)ccc1OCc1ccc(F)cc1.NCCc1ccncc1>>CC(C)Cc1cc(C(=O)NCCc2ccncc2)ccc1OCc1ccc(F)cc1 -US20100069352A1,4,CCOC(=O)CC(=O)C(Cl)C(=O)OCC.NC(=S)c1ccc(Cl)cc1>>CCOC(=O)Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)OCC -US20130310331A1,9,CCOC(=O)C(=O)Cc1ccccc1F>>CCOC(=O)C(=O)Cc1ccccc1 -US06211216B1,10,COC(=O)c1ccc(S(C)(=O)=O)c(C)c1Cl.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(S(C)(=O)=O)c(CBr)c1Cl -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)nc3)c(F)c2)OC1(C)C.NCC1(S(=O)(=O)c2ccccc2Br)CCCC1>>NCC1(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)CCCC1 -US07727997B2,2,CCCCN1CCOc2c(C#N)cc(C(=O)O)cc21.CCc1cccc(CNC[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)c1>>CCCCN1CCOc2c(C#N)cc(C(=O)N[C@@H](Cc3cc(F)cc(F)c3)[C@H](O)CNCc3cccc(CC)c3)cc21 -US06642395B1,1,CS(=O)(=O)OC[C@H](O)c1cccc(Cl)c1>>Clc1cccc([C@@H]2CO2)c1 -US20050267095A1,7,N#CC1(c2ccc(OCCCN3CCSCC3)cc2)CCOCC1>>NCC1(c2ccc(OCCCN3CCSCC3)cc2)CCOCC1 -US04780471,1,C=C(c1cc(F)ccc1O)n1ccnc1.ClCc1ccc(Cl)cc1Cl>>C=C(c1cc(F)ccc1OCc1ccc(Cl)cc1Cl)n1ccnc1 -US04710573,1,CC(=O)N1CCC(C(=O)c2ccc(Br)cc2F)CC1.NNc1ccccc1>>CC(=O)N1CCC(C(=NNc2ccccc2)c2ccc(Br)cc2F)CC1 -US06545009B1,4,COC(=O)c1cccc(C(N)=S)c1.O=C(CBr)c1ccc(F)c(F)c1>>COC(=O)c1cccc(-c2nc(-c3ccc(F)c(F)c3)cs2)c1 -US20050250836A1,3,C[Mg+].Cn1c(C=O)cc2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O>>CC(O)c1cc2c3c(c(-c4ccccc4Cl)cc2n1C)C(=O)NC3=O -US20080045546A1,6,COC(=O)c1ccc(-c2ccc(OC(F)(F)F)cc2)nc1>>O=C(O)c1ccc(-c2ccc(OC(F)(F)F)cc2)nc1 -US20070088044A1,6,O=c1[nH]cnc2cc(F)cc(OCc3ccccc3)c12>>O=c1[nH]cnc2cc(F)cc(O)c12 -US20140371201A1,1,CCI.O=c1ccc2cc(SCc3ccccc3)ccc2n1-c1cc(F)c(-c2cccc(F)c2)cc1O>>CCOc1cc(-c2cccc(F)c2)c(F)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21 -US08901124B2,1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.COc1ccc(Nc2cc(Cl)nnc2C(N)=O)nc1C(C)C>>COc1ccc(Nc2cc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)nnc2C(N)=O)nc1C(C)C -US20100130446A1,3,Brc1ccc(C2OCCO2)cn1.CN(C)C=O>>O=Cc1ccc(C2OCCO2)cn1 -US07435744B2,2,COc1ccc(CC2CCNCC2)cc1.O=C(O)C(=O)Nc1ccc2[nH]c(=O)oc2c1>>COc1ccc(CC2CCN(C(=O)C(=O)Nc3ccc4[nH]c(=O)oc4c3)CC2)cc1 -US04624954,2,Cc1c2n(c3ccccc13)CCCC2NC(C)C.O=CO>>Cc1c2n(c3ccccc13)CCCC2N(C=O)C(C)C -US04507312,2,CC(=O)SCC(C)C(=O)O.CC(C)(C)OC(=O)CNCC1CCCO1>>CC(=O)SCC(C)C(=O)N(CC(=O)OC(C)(C)C)CC1CCCO1 -US20120094980A1,7,COC(=O)c1ccnc(-c2cc(NC(=O)c3ccc(C(F)(F)F)nc3C)ccc2Cl)c1>>Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2cc(CO)ccn2)c1 -US20060276498A1,3,CC#C[Sn](CCCC)(CCCC)CCCC.N#Cc1cnc2cnc(NCCN3CCOCC3)cc2c1Nc1cccc(I)c1>>CC#Cc1cccc(Nc2c(C#N)cnc3cnc(NCCN4CCOCC4)cc23)c1 -US04163789,2,COC(=O)c1cc(Cl)c(NC(C)=O)cc1OC.NC1CCN(CC2CCCCC2)CC1>>COc1cc(NC(C)=O)c(Cl)cc1C(=O)NC1CCN(CC2CCCCC2)CC1 -US20090137580A1,1,Cn1ccc2ncnc(Cl)c21.Nc1ccc(O)c2ccccc12>>Cn1ccc2ncnc(Oc3ccc(N)c4ccccc34)c21 -US20150057260A1,3,CCOC(=O)c1cc(Cl)nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1.OB(O)c1ccn[nH]1>>CCOC(=O)c1cc(-c2ccn[nH]2)nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1 -US20080090863A1,6,CCN(C)c1cc(N[C@@H]2CC[C@H](NCc3ccccc3)CC2)ncc1C>>CCN(C)c1cc(N[C@@H]2CC[C@H](N)CC2)ncc1C -US08349886B2,1,Ic1ccnc2[nH]ncc12.O=S([O-])C1CC1>>O=S(=O)(c1ccnc2[nH]ncc12)C1CC1 -US08030354B2,3,CC(C)(C)[Si](C)(C)Oc1cc(F)cc(C=O)c1F.CC[Mg+]>>CCC(O)c1cc(F)cc(O[Si](C)(C)C(C)(C)C)c1F -US20100144707A1,7,COc1cc2nc(-c3cccc([N+](=O)[O-])c3)nc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)c2cc1OCCN(C)C>>COc1cc2nc(-c3cccc(N)c3)nc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)c2cc1OCCN(C)C -US06432993B1,2,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-n3ccnc3)cc2)ccc1N.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-n3ccnc3)cc2)ccc1NC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1 -US20150111857A1,7,CC1(C)OCC(Cn2cc([N+](=O)[O-])cn2)O1>>CC1(C)OCC(Cn2cc(N)cn2)O1 -US20090149486A1,6,CC(C)(C)OC(=O)C1CC1CCCCCSc1ncc(-c2ccccc2)c(-c2ccccc2)n1>>O=C(O)C1CC1CCCCCSc1ncc(-c2ccccc2)c(-c2ccccc2)n1 -US20050143407A1,2,CCO.COc1c(F)c(F)cc(C(=O)O)c1F>>CCOC(=O)c1cc(F)c(F)c(OC)c1F -US20130158040A1,3,C#C[Si](C)(C)C.O=S(=O)(Oc1c(F)cccc1Cl)C(F)(F)F>>C[Si](C)(C)C#Cc1c(F)cccc1Cl -US08063071B2,3,CC(C)C(=O)c1cc(Br)cs1.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(B4OC(C)(C)C(C)(C)O4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(C(=O)C(C)C)c4)cc23)CC1 -US20050032787A1,1,OCCBr.c1ccc2[nH]ccc2c1>>OCCn1ccc2ccccc21 -US20080255153A1,1,C=CC#N.O=C(NCCO)c1cnn2cc(Cc3ccc(Br)cc3)cnc12>>N#CCCOCCNC(=O)c1cnn2cc(Cc3ccc(Br)cc3)cnc12 -US08575208B2,3,CC(C)(C)OC(=O)[C@@H]1CC(=O)CN1C(=O)OC(C)(C)C.CCOC(=O)CBr>>CCOC(=O)CC1(O)C[C@@H](C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)C1 -US04904410,1,CC(F)C(=O)O.CCCCCCCCCCc1cnc(-c2ccc(O)cc2)nc1>>CCCCCCCCCCc1cnc(-c2ccc(OC(=O)C(C)F)cc2)nc1 -US08614209B2,3,O=C(O)c1csc(Br)c1.OB(O)c1ccc(F)nc1>>O=C(O)c1csc(-c2ccc(F)nc2)c1 -US05153210,1,CC(=O)Cc1ccc(OCc2cc(C)c(C(N)=O)o2)cc1.NCC(O)c1cccc(Cl)c1>>Cc1cc(COc2ccc(CC(C)NCC(O)c3cccc(Cl)c3)cc2)oc1C(N)=O -US20110076291A1,3,CC(C)n1ncnc1-c1nc2c(s1)CCOc1ccc(Br)cc1-2.O=c1[nH]cc(B(O)O)c(=O)[nH]1>>CC(C)n1ncnc1-c1nc2c(s1)CCOc1ccc(-c3c[nH]c(=O)[nH]c3=O)cc1-2 -US08137583B2,7,O=C1CCC(c2cccc(F)c2)CC1>>OC1CCC(c2cccc(F)c2)CC1 -US07332492B2,6,CCOC(=O)CN1CCC(Cc2ccccc2)C1=O>>O=C(O)CN1CCC(Cc2ccccc2)C1=O -US07229987B2,1,C1CSCCN1.ClCCCCOc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1>>c1ccc(OCCSCc2nnc(-c3ccc(OCCCCN4CCSCC4)cc3)o2)cc1 -US04870183,2,COC(=O)[C@@H](N)Cc1c[nH]cn1.O=C(O)C(Cc1ccccc1F)Cc1ccccc1F>>COC(=O)[C@H](Cc1c[nH]cn1)NC(=O)C(Cc1ccccc1F)Cc1ccccc1F -US20130267510A1,6,COCOc1cccc2c1C1(CC1)CO2>>Oc1cccc2c1C1(CC1)CO2 -US07829584B2,7,N#Cc1cncc(Cl)c1>>NCc1cncc(Cl)c1 -US20120184542A1,2,CC(C)(C)OC(=O)NCC(N)c1ccccc1.COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CNC(=O)OC(C)(C)C)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1 -US06399318B1,7,O=C(OC1CCCCC1)c1ccc([N+](=O)[O-])cc1C(=O)OC1CCCCC1>>Nc1ccc(C(=O)OC2CCCCC2)c(C(=O)OC2CCCCC2)c1 -US07902203B2,1,N#Cc1cccc(C=O)c1.Nn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc21>>N#Cc1cccc(C=Nn2c(=O)c(C3=NS(=O)(=O)c4ccccc4N3)c(O)c3sccc32)c1 -US20120122846A1,1,Clc1nc(Cl)c2occc2n1.NCC(F)F>>FC(F)CNc1nc(Cl)nc2ccoc12 -US20090099181A1,3,C#Cc1ccc(NC(=O)c2ccc(F)cc2)cc1.CS(=O)(=NC(=O)c1cncc(Br)c1)c1ccccc1>>C[S@@](=O)(=NC(=O)c1cncc(C#Cc2ccc(NC(=O)c3ccc(F)cc3)cc2)c1)c1ccccc1 -US20080188481A1,3,CCCC[Sn](CCCC)(CCCC)c1nccs1.N#CC(=C1CCN(C(=O)C(=O)c2c[nH]c3c(Cl)ccnc23)CC1)c1ccccc1>>N#CC(=C1CCN(C(=O)C(=O)c2c[nH]c3c(-c4nccs4)ccnc23)CC1)c1ccccc1 -US04042586,1,Nc1ncc(Br)nc1N1CCOCC1.OCc1ccccc1>>Nc1ncc(OCc2ccccc2)nc1N1CCOCC1 -US05597918,3,CC(=O)Cl.O=C1CC2CCc3sccc3C2=NN1c1ccc(Cl)cc1>>CC(=O)c1cc2c(s1)CCC1CC(=O)N(c3ccc(Cl)cc3)N=C21 -US07935722B2,4,CC(C)C(=O)NC1CCC(=O)CC1.NNc1ccc(Br)cc1>>CC(C)C(=O)NC1CCc2[nH]c3ccc(Br)cc3c2C1 -US05254561,3,C[Mg+].O=C1CCc2ccccc21>>CC1(O)CCc2ccccc21 -US20150252044A1,3,COc1cccc(B(O)O)c1.O=C(NCc1ccncc1)c1ccc2cncc(Br)c2n1>>COc1cccc(-c2cncc3ccc(C(=O)NCc4ccncc4)nc23)c1 -US08003662B2,2,CNC(=O)c1ccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)cc1.Cn1cccc(C(=O)O)c1=O>>CNC(=O)c1ccc(-c2cc3nccc(Oc4ccc(NC(=O)c5cccn(C)c5=O)cc4F)c3s2)cc1 -US05670675,5,O=C(CCc1ccccc1)CCc1ccccc1.OCCO>>c1ccc(CCC2(CCc3ccccc3)OCCO2)cc1 -US04321382,1,CNC.O=C1CCN2CCc3ccccc3C2(c2ccc(F)cc2)C1>>CN(C)C1CCN2CCc3ccccc3C2(c2ccc(F)cc2)C1 -US04711890,2,CCC(C)NC.O=C(O)c1cc(-c2ccccc2Cl)nc2ccccc12>>CCC(C)N(C)C(=O)c1cc(-c2ccccc2Cl)nc2ccccc12 -US20140336177A1,3,CC(C)(C)OC(=O)C[Zn+].Nc1ncc(Br)cn1>>CC(C)(C)OC(=O)Cc1cnc(N)nc1 -US20090099205A1,6,CONC(=O)N(Cc1ccsc1)C1CCN(CCCN2C(=O)c3ccccc3C2=O)CC1>>CONC(=O)N(Cc1ccsc1)C1CCN(CCCN)CC1 -US20070244153A1,2,CC(C)[C@@H](CN)NC(=O)OC(C)(C)C.N#Cc1ccc(C(=O)Cl)cc1>>CC(C)[C@@H](CNC(=O)c1ccc(C#N)cc1)NC(=O)OC(C)(C)C -US20080161302A1,2,CCN(CC)C(=O)Cl.O=[N+]([O-])c1cccc(O)c1>>CCN(CC)C(=O)Oc1cccc([N+](=O)[O-])c1 -US20130157996A1,2,N[C@@H](c1ccc(C(F)(F)F)cc1)c1ncccc1C(F)(F)F.O=C(O)c1ccc2c(c1)CNC2=O>>O=C(N[C@@H](c1ccc(C(F)(F)F)cc1)c1ncccc1C(F)(F)F)c1ccc2c(c1)CNC2=O -US07737136B2,5,CCOC(=O)C(F)(F)F.N[C@@H]1CCCN2c3cc(Cl)ccc3Nc3ccccc3[C@H]12>>O=C(N[C@@H]1CCCN2c3cc(Cl)ccc3Nc3ccccc3[C@H]12)C(F)(F)F -US20040053972A1,1,ICCCc1ccc(OCc2ccccc2)cc1.c1c[nH]nn1>>c1ccc(COc2ccc(CCCn3ccnn3)cc2)cc1 -US20130030171A1,7,O=[N+]([O-])c1ccc(OCCN2CCCC2)c(F)c1>>Nc1ccc(OCCN2CCCC2)c(F)c1 -US20050124605A1,1,C=O.Cc1cc(C)nc(O[C@H](C(=O)O)[C@@]2(c3ccccc3)NCC(=O)N(C)c3ccccc32)n1>>Cc1cc(C)nc(O[C@H](C(=O)O)[C@]2(c3ccccc3)c3ccccc3N(C)C(=O)CN2C)n1 -US08022062B2,3,C#Cc1ccc(F)cc1.CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCc3ccc(Br)cn3)c2CC1>>CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCc3ccc(C#Cc4ccc(F)cc4)cn3)c2CC1 -US20130053381A1,1,CCC(OC)c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)(F)F.CCCC(=O)Cl>>CCCC(=O)N(n1c(=O)[nH]c2cc(C(F)(F)F)c(C(CC)OC)cc2c1=O)S(C)(=O)=O -US20030092712A1,7,COC(=O)c1cc(-c2ccccc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)NC2>>O=C1NCc2c(-c3ccccc3Cl)cc(CO)cc2N1c1c(Cl)cccc1Cl -US20120040960A1,2,NCC(=O)NC1CN(C2CCC(c3ccccc3)CC2)C1.O=C(O)c1cc(Br)cc(C(F)(F)F)c1>>O=C(CNC(=O)c1cc(Br)cc(C(F)(F)F)c1)NC1CN(C2CCC(c3ccccc3)CC2)C1 -US20020058809A1,1,CN1CCC(C#N)(NC(=O)C(N)CC2CCCCC2)CC1.O=S1(=O)N=C(Cl)c2ccccc21>>CN1CCC(C#N)(NC(=O)C(CC2CCCCC2)NC2=NS(=O)(=O)c3ccccc32)CC1 -US07109229B2,9,BrC(Br)(Br)Br.COc1ccc2c(C3=C(c4cccc5ccn(C)c45)C(=O)NC3=O)cn(CCO)c2c1>>COc1ccc2c(C3=C(c4cccc5ccn(C)c45)C(=O)NC3=O)cn(CCBr)c2c1 -US20100145047A1,2,CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(N)cc2)C1.CCOc1cccc2c1cc(C(=O)O)n2CC>>CCOc1cccc2c1cc(C(=O)Nc1ccc(O[C@H]3CCN(C(=O)OC(C)(C)C)C3)cc1)n2CC -US05635197,3,CN1C(=O)CC[C@]2(C)c3ccc(Br)cc3CC[C@@H]12.OB(O)c1cccc(Cl)c1Cl>>CN1C(=O)CC[C@]2(C)c3ccc(-c4cccc(Cl)c4Cl)cc3CC[C@@H]12 -US20060142581A1,1,CC(C)(C)OC(=O)NCCCCc1ccc(S)cc1.NC(=O)CCBr>>CC(C)(C)OC(=O)NCCCCc1ccc(SCCC(N)=O)cc1 -US20090281060A1,2,CCCN=C=O.c1cc(-c2noc(C3CCNCC3)n2)ccn1>>CCCNC(=O)N1CCC(c2nc(-c3ccncc3)no2)CC1 -US06544976B1,2,COC(=O)[C@@H]1CCN1.O=S(=O)(Cl)Cc1ccccc1>>COC(=O)[C@@H]1CCN1S(=O)(=O)Cc1ccccc1 -US20020193398A1,9,[N-]=[N+]=NCc1ccccc1-c1csnn1>>NCc1ccccc1-c1csnn1 -US07820699B2,2,CC(C)(C)OC(=O)N1CC[C@H](CN)C1.O=C(O)c1cc(Br)c(Br)s1>>CC(C)(C)OC(=O)N1CC[C@H](CNC(=O)c2cc(Br)c(Br)s2)C1 -US06211199B1,2,COc1cc(C(=O)N2CCC(CCO)(c3ccccc3)C2)cc(OC)c1OC.CS(=O)(=O)Cl>>COc1cc(C(=O)N2CCC(CCOS(C)(=O)=O)(c3ccccc3)C2)cc(OC)c1OC -US20150025068A1,2,COC(=O)c1ccc(N)cc1O.COc1ccc(S(=O)(=O)Cl)cc1Br>>COC(=O)c1ccc(NS(=O)(=O)c2ccc(OC)c(Br)c2)cc1O -US20060276464A1,1,C1CCNC1.CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccc(Cl)nc2)CC1>>CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccc(N3CCCC3)nc2)CC1 -US20020052378A1,4,CCOC(=O)C(CC(C)C)C(N)=S.O=C(CBr)c1ccccc1>>CCOC(=O)C(CC(C)C)c1nc(-c2ccccc2)cs1 -US20130039906A1,1,Brc1cc2c(I)nn(C3CCCCO3)c2cn1.CC(=O)N1CCNC1=O>>CC(=O)N1CCN(c2nn(C3CCCCO3)c3cnc(Br)cc23)C1=O -US09085578B2,3,CC(=O)CC(=O)Nc1ccccc1Cl.CN(C)C=O>>CC(=O)C(=CN(C)C)C(=O)Nc1ccccc1Cl -US20080214542A1,1,CCOC(=O)CCCCCBr.N#Cc1ccccc1N1CCNCC1>>CCOC(=O)CCCCCN1CCN(c2ccccc2C#N)CC1 -US20150191478A1,1,C1CNCCN1.CCOC(OCC)c1cc2cncc(I)c2o1>>CCOC(OCC)c1cc2cncc(N3CCNCC3)c2o1 -US07196099B2,2,CC(=O)OC1NC(=O)C1N.O=C(O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1>>CC(=O)OC1NC(=O)C1NC(=O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1 -US20070173486A1,6,Cc1ccccc1C(OC1CCN(Cc2ccccc2)CC1)c1ccccc1>>Cc1ccccc1C(OC1CCNCC1)c1ccccc1 -US20050159460A1,2,CC(C)OC(=O)Cl.CC(C)[C@H](N)C(=O)O>>CC(C)OC(=O)N[C@H](C(=O)O)C(C)C -US20090291938A1,1,COC(=O)c1ccc([N+](=O)[O-])c(O)c1.FC(F)I>>COC(=O)c1ccc([N+](=O)[O-])c(OC(F)F)c1 -US06914065B2,9,FC(F)(F)c1cc(Cl)ncn1.N>>Nc1cc(C(F)(F)F)ncn1 -US05852011,6,COC(=O)c1cccc(N(CCCl)CCCl)c1>>O=C(O)c1cccc(N(CCCl)CCCl)c1 -US20090111791A1,1,CC(C)(C)OC(=O)N1CCC(O)C1.Clc1ncccn1>>CC(C)(C)OC(=O)N1CCC(Oc2ncccn2)C1 -US20080004330A1,7,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)O)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](CO)C1 -US04857530,1,C#CCBr.Nc1ccc(OC(F)(F)F)cc1>>C#CCNc1ccc(OC(F)(F)F)cc1 -US20090181942A1,6,COC(=O)CCc1cn(CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)nn1>>COc1cccc([C@H]2O[C@H](CCn3cc(CCC(=O)O)nn3)c3cccn3-c3ccc(Cl)cc32)c1OC -US08546376B2,1,CI.O=c1c(I)c(-c2ccccc2)oc2c1ccn1c(=O)[nH]nc21>>Cn1nc2c3oc(-c4ccccc4)c(I)c(=O)c3ccn2c1=O -US06713474B2,1,Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCNCC1.O=Cc1ncc[nH]1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCN(Cc2ncc[nH]2)CC1 -US04587346,9,CCCCCCCCCCCCc1cc(C)cc(-n2nc3ccc(Cl)cc3n2)c1O>>CCCCCCCCCCCCc1cc(C)cc(-n2nc3ccccc3n2)c1O -US20150259464A1,2,CCCCCCC(O)CCCCCCCCCCC(=O)O.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CCCCCCC(CCCCCCCCCCC(=O)O)OC(=O)c1ccc([N+](=O)[O-])cc1 -US20080194647A1,3,C[Si](C)(C)C#Cc1cncc(C#N)c1.O=Cc1cc(I)ccc1F>>N#Cc1cncc(C#Cc2ccc(F)c(C=O)c2)c1 -US20140249154A1,4,NC(=S)Nc1ccccn1.O=C(CBr)c1ccccn1>>c1ccc(Nc2nc(-c3ccccn3)cs2)nc1 -US20090048343A1,7,O=C(O)C(O)=Cc1cccc([N+](=O)[O-])c1>>O=C(O)C(O)Cc1cccc([N+](=O)[O-])c1 -US05373017,6,CN(CCn1ccnc1)Cc1ccccc1>>CNCCn1ccnc1 -US07910613B2,2,CCC(=O)Cl.Cc1nc(-c2sc(N)nc2-c2ccccc2)no1>>CCC(=O)Nc1nc(-c2ccccc2)c(-c2noc(C)n2)s1 -US20140288046A1,1,CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1.CN(C)C1CCNC1>>CN(C)C1CCN(c2nc(C(C)(C)C)nc3c2nnn3Cc2ccccc2Cl)C1 -US20150057260A1,1,CCOC(=O)c1nc(Cl)ncc1F.COCCN>>CCOC(=O)c1nc(Cl)ncc1NCCOC -US04171375,1,C1=COCCC1.COC(=O)CCCCCCC1=CCC(O)C1=O>>COC(=O)CCCCCCC1=CCC(OC2CCCCO2)C1=O -US05183902,2,CN=C=O.FC(F)(F)c1ccccc1OC1CNC1>>CNC(=O)N1CC(Oc2ccccc2C(F)(F)F)C1 -US06005116,1,CC(C)(C)OC(=O)NCCO.CCCCCc1c(O)noc1-c1ccccc1>>CCCCCc1c(OCCNC(=O)OC(C)(C)C)noc1-c1ccccc1 -US20120309738A1,1,Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-].OC[C@H]1CCCN1>>Nc1cc(N2CCC[C@@H]2CO)c(Cl)cc1[N+](=O)[O-] -US20070060566A1,3,Clc1cnccn1.O=C(O)c1cccc(B(O)O)c1>>O=C(O)c1cccc(-c2cnccn2)c1 -US20090131468A1,3,COCCOCCOc1cc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cnc1Cl.OB(O)c1cc2ccccc2o1>>COCCOCCOc1cc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cnc1-c1cc2ccccc2o1 -US20030125550A1,1,BrCc1ccccc1.COC(=O)CCCCCOc1ccc2nc(S)n(-c3ccc(C)cc3)c2c1>>COC(=O)CCCCCOc1ccc2nc(SCc3ccccc3)n(-c3ccc(C)cc3)c2c1 -US06107329,2,NCC(=O)N1CCSC1.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>O=C(NCC(=O)N1CCSC1)c1cc2cc(Cl)ccc2[nH]1 -US20100105666A1,9,O=C1NC(=O)N2c3ccc(Cl)cc3C3CCN4CCCC1C4C32>>O=C1NC(=O)N2c3ccccc3C3CCN4CCCC1C4C32 -US20110118261A1,1,CN(C)C1CCN(c2ccc(-n3ccc(O)cc3=O)cn2)C1.OCc1ccc(F)cn1>>CN(C)C1CCN(c2ccc(-n3ccc(OCc4ccc(F)cn4)cc3=O)cn2)C1 -US20110046210A1,2,CC(C)(N)C(=O)OC1CCCC1.O=C(O)c1cccc(B(O)O)c1>>CC(C)(NC(=O)c1cccc(B(O)O)c1)C(=O)OC1CCCC1 -US20090324581A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc2[nH]ccc2c1>>COC(=O)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1 -US08076489B2,2,CC(C)Oc1nc2cc(OC(C)(C)C)cc([C@H](O)CO)c2s1.CS(=O)(=O)Cl>>CC(C)Oc1nc2cc(OC(C)(C)C)cc([C@H](O)COS(C)(=O)=O)c2s1 -US20130252944A1,4,COc1ccc(Cn2cc3c(n2)CCCCC(Br)C3=O)cc1.Cc1ccnc(NC(N)=S)n1>>COc1ccc(Cn2cc3c(n2)CCCCc2sc(Nc4nccc(C)n4)nc2-3)cc1 -US20150080365A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(F)nc(Br)c1>>Cc1cc(F)nc(N2CCN(C(=O)OC(C)(C)C)CC2)c1 -US04772626,7,COC(=O)CC(O)CC(=O)/C=C/c1c(C)cc(C)cc1-c1ccc(F)c(CO[Si](C)(C)C(C)(C)C)c1>>COC(=O)CC(O)CC(O)/C=C/c1c(C)cc(C)cc1-c1ccc(F)c(CO[Si](C)(C)C(C)(C)C)c1 -US05175173,6,COC(=O)c1cc(Cl)cc2ccoc12>>O=C(O)c1cc(Cl)cc2ccoc12 -US05420126,1,CC1(C)CNc2cc([N+](=O)[O-])ccc2O1.[O-][n+]1ccccc1Br>>CC1(C)CN(c2cccc[n+]2[O-])c2cc([N+](=O)[O-])ccc2O1 -US05965555,1,C#CCBr.CN1CCNCC1>>C#CCN1CCN(C)CC1 -US07723368B2,4,ClCCOCCCl.Nc1cc(Br)ccc1F>>Fc1ccc(Br)cc1N1CCOCC1 -US20110082156A1,6,Cc1cnc(C(=O)NCCN(C)CCNC(=O)OC(C)(C)C)c[n+]1[O-]>>Cc1cnc(C(=O)NCCN(C)CCN)c[n+]1[O-] -US20130338196A1,1,COC(=O)C1Cc2ccc(O)cc2C1.OB(O)c1ccccc1>>COC(=O)C1Cc2ccc(Oc3ccccc3)cc2C1 -US06057364,6,COC(=O)C12CC3CC(F)(CC(F)(C3)C1)C2>>O=C(O)C12CC3CC(F)(CC(F)(C3)C1)C2 -US20040259912A1,7,COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1>>COC(=O)c1cc(N)ccc1OC(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1 -US06291455B1,1,COc1cc2ncnc(Cl)c2cc1OC.Nc1ccc(Cl)c(O)c1>>COc1cc2ncnc(Nc3ccc(Cl)c(O)c3)c2cc1OC -US20110053980A1,1,CNC.Cc1nn(C)c(C)c1-c1ccc2c(c1)C(=O)CC2>>Cc1nn(C)c(C)c1-c1ccc2c(c1)C(N(C)C)CC2 -US20060069116A1,4,CC(C)(C)OC(=O)N1CCC(C(=O)C(F)(F)F)C(=O)C1.NN>>CC(C)(C)OC(=O)N1CCc2c(C(F)(F)F)n[nH]c2C1 -US04054719,1,CC(=O)O.O=C(CCl)c1ccc(Cl)c(Cl)c1>>CC(=O)OCC(=O)c1ccc(Cl)c(Cl)c1 -US07863450B2,1,CC1CCCN1CCCO.Clc1ccc(C2=NC3(CCCCC3)CO2)cn1>>CC1CCCN1CCCOc1ccc(C2=NC3(CCCCC3)CO2)cn1 -US20110028450A1,1,C#CCBr.CC(C)(C)OC(=O)NCCO[Si](C)(C)C(C)(C)C>>C#CCN(CCO[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C -US20130116236A1,1,CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1.OCC1CNCCO1>>CC(C)(C)c1nc(N2CCOC(CO)C2)c2nnn(Cc3ccccc3Cl)c2n1 -US20100121048A1,6,COC(=O)CC1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1cc(C)n(-c2ccccc2)c1-c1ccccc1>>Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2CC(=O)O)c(-c2ccccc2)n1-c1ccccc1 -US05484942,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(C2(c3ccccc3)CCSC3CNCC32)cc1>>CC(C)(C)OC(=O)N1CC2SCCC(c3ccccc3)(c3ccccc3)C2C1 -US04772600,9,N.O=C(O)Cn1c(-c2ccc(Br)o2)nc2cccnc21>>NC(=O)Cn1c(-c2ccc(Br)o2)nc2cccnc21 -US07531545B2,1,CC(C)(C)OC(=O)CC[C@H](N)C1CCCCC1.O=Cc1cc(Oc2ccccc2)ncc1[N+](=O)[O-]>>CC(C)(C)OC(=O)CC[C@H](NCc1cc(Oc2ccccc2)ncc1[N+](=O)[O-])C1CCCCC1 -US20080045537A1,4,Nc1cccc(C(=O)O)c1N.O=C(O)CCl>>O=C(O)c1cccc2[nH]c(CCl)nc12 -US20100292279A1,2,NS(=O)(=O)c1ccccc1S(N)(=O)=O.O=C(O)c1ccc(Br)c(CO)c1>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)c(CO)c1 -US07629375B2,3,COCOc1ccc(C=O)cc1OCOC.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1ccc(OCOC)c(OCOC)c1 -US07557213B2,1,N#Cc1cccc(CBr)n1.O=C(c1ccc2c(c1)OCCO2)c1c[nH]c2ccccc2c1=O>>N#Cc1cccc(Cn2cc(C(=O)c3ccc4c(c3)OCCO4)c(=O)c3ccccc32)n1 -US08471005B2,3,CC1(C)OB(c2ccc3cnc(Nc4ccc(N5CCOCC5)cc4)nn23)OC1(C)C.Cc1nc(Br)cn1C>>Cc1nc(-c2ccc3cnc(Nc4ccc(N5CCOCC5)cc4)nn23)cn1C -US20060178510A1,6,CC(C)(C)OC(=O)N1CCO[C@H](Cc2ccc(OCc3ccccc3)cc2)C1>>CC(C)(C)OC(=O)N1CCO[C@H](Cc2ccc(O)cc2)C1 -US20090197834A1,9,BrC(Br)(Br)Br.CCC(CC)n1cc(CCCCO)c(=O)c2cc(F)c(NC3CCCCC3)cc21>>CCC(CC)n1cc(CCCCBr)c(=O)c2cc(F)c(NC3CCCCC3)cc21 -US05864039,3,O=C(Cl)CCCCCBr.c1ccccc1>>O=C(CCCCCBr)c1ccccc1 -US20100160255A1,6,CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(NC(=O)OC(C)(C)C)sc5ccccc45)CC3)C2)N=C1C>>CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(N)sc5ccccc45)CC3)C2)N=C1C -US07332498B2,2,CC(C)C(NCC(C)(C)N)c1nc2nc(Cl)cnc2c(=O)n1Cc1ccccc1.Cc1ccc(C(=O)Cl)cc1F>>Cc1ccc(C(=O)NC(C)(C)CNC(c2nc3nc(Cl)cnc3c(=O)n2Cc2ccccc2)C(C)C)cc1F -US09150555B2,3,CC1(C)OB(C2=CCC(N3CCOCC3)CC2)OC1(C)C.Cc1c(C(=O)Nc2cnc(Cl)c(C#N)c2)cnn1-c1ccc(C(F)(F)F)cn1>>Cc1c(C(=O)Nc2cnc(C3=CCC(N4CCOCC4)CC3)c(C#N)c2)cnn1-c1ccc(C(F)(F)F)cn1 -US08258134B2,2,CC1(C)OC[C@@H](Cn2ccc(N)n2)O1.O=C(O)C(CC1CCCC1)n1ncc(Oc2ncccc2F)cc1=O>>CC1(C)OC[C@@H](Cn2ccc(NC(=O)C(CC3CCCC3)n3ncc(Oc4ncccc4F)cc3=O)n2)O1 -US20070093521A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.NS(=O)(=O)c1cccc2nc(Cl)oc12>>CC(C)(C)OC(=O)N1CCC(Nc2nc3cccc(S(N)(=O)=O)c3o2)CC1 -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(F)cc4)CC3)C(=O)C(C)(C)C2)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccc(F)cc4)NC(=O)c4c[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)C(C)(C)C2)cc1OC -US20080255114A1,7,COC(=O)c1cc(F)cc(O)c1[N+](=O)[O-]>>COC(=O)c1cc(F)cc(O)c1N -US20090042929A1,1,O=C(CBr)C12CC3CC(CC(C3)C1)C2.SCc1ccc(Cl)cc1>>O=C(CSCc1ccc(Cl)cc1)C12CC3CC(CC(C3)C1)C2 -US20100298550A1,9,CC(=O)O[C@H]1[C@H](OC(C)=O)O[C@H](CCl)[C@H]1OC(C)=O>>CC(=O)O[C@H]1[C@H](OC(C)=O)O[C@H](C)[C@H]1OC(C)=O -US20150087658A1,9,Cn1nnc(-c2c(Cl)ncnc2Cl)n1.N>>Cn1nnc(-c2c(N)ncnc2Cl)n1 -US20090247507A1,6,CC(C)(C)OC(=O)N1CCN(Cc2ccc(-c3nc4c(N5CCN(Cc6cccnc6)CC5)c(Br)cnc4[nH]3)cc2)CC1>>Brc1cnc2[nH]c(-c3ccc(CN4CCNCC4)cc3)nc2c1N1CCN(Cc2cccnc2)CC1 -US04001426,1,CCN(CC)CCCCl.Oc1ccc(-c2cc3ccccc3o2)cc1>>CCN(CC)CCCOc1ccc(-c2cc3ccccc3o2)cc1 -US06284785B1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Fc1ccccc1C1CCCN1>>Cc1ccc(S(=O)(=O)N2CCCC2c2ccccc2F)cc1 -US20150025056A1,1,COC(=O)[C@H]1C[C@@H](O)CN(C(=O)OC(C)(C)C)[C@@H]1C(=O)N1CC=C(c2ccccc2)CC1.Oc1ccncc1>>COC(=O)[C@H]1C[C@H](Oc2ccncc2)CN(C(=O)OC(C)(C)C)[C@@H]1C(=O)N1CC=C(c2ccccc2)CC1 -US20100069412A1,1,CC=O.O=C(Cc1cc(Nc2ncnc3cc(OCCCNCCCO)ccc23)n[nH]1)Nc1cccc(F)c1>>CCN(CCCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1 -US20100041714A1,6,Cc1ccc(-c2ccc(S(=O)(=O)N[C@@H]3CCCc4c(OCC(=O)OC(C)(C)C)cccc43)cc2)cc1>>Cc1ccc(-c2ccc(S(=O)(=O)N[C@@H]3CCCc4c(OCC(=O)O)cccc43)cc2)cc1 -US20070293521A1,1,Fc1cnc(Cl)nc1Nc1ccc2c(c1)OCCO2.Nc1cccc(N)c1>>Nc1cccc(Nc2ncc(F)c(Nc3ccc4c(c3)OCCO4)n2)c1 -US20090137577A1,1,COC(=O)c1ccc(C=O)cc1.c1ccc2c(c1)CCN2>>COC(=O)c1ccc(CN2CCc3ccccc32)cc1 -US20090247519A1,6,CC(C)(C)OC(=O)NCCNc1cc(-c2ccccc2O)nc2ccccc12>>NCCNc1cc(-c2ccccc2O)nc2ccccc12 -US20080021217A1,7,O=[N+]([O-])c1cccc2c(-c3ccncc3)n[nH]c12>>Nc1cccc2c(-c3ccncc3)n[nH]c12 -US07030128B2,3,CCCC[Sn](CCCC)(CCCC)c1cnc2nc(C(F)(F)F)ccn12.N#Cc1ccccc1-c1cc(Cl)ccn1>>N#Cc1ccccc1-c1cc(-c2cnc3nc(C(F)(F)F)ccn23)ccn1 -US07125870B2,7,COC(=O)C=CC1(C(C)(C)O[SiH2]C(C)(C)C)CC(c2ccc(OCc3cc(C)nc4ccccc34)cc2)=NO1>>COC(=O)CCC1(C(C)(C)O[SiH2]C(C)(C)C)CC(c2ccc(OCc3cc(C)nc4ccccc34)cc2)=NO1 -US20120276018A1,1,COc1ccc(C(OC(=O)N[C@H]2CN3CCC2CC3)c2ccccc2)cc1.O=C(CCl)c1cccs1>>COc1ccc(C(OC(=O)N[C@H]2C[N+]3(CC(=O)c4cccs4)CCC2CC3)c2ccccc2)cc1 -US20100216788A1,2,CC(C)(O)CC(=O)O.NCCn1ccc2ncnc(Nc3ccc4c(ccn4Cc4cccc(F)c4)c3)c21>>CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc4c(ccn4Cc4cccc(F)c4)c3)c21 -US06867321B2,1,C=COCC.OCCI>>CCOC(C)OCCI -US20100261772A1,6,CCOC(=O)CCCOc1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(F)cc2)cc1>>CC1(C)CC(=C(c2ccc(F)cc2)c2ccc(OCCCC(=O)O)cc2)CC(C)(C)C1 -US20050176701A1,6,CCOC(=O)CCC1=CCCCC1>>O=C(O)CCC1=CCCCC1 -US07795283B2,2,COC(=O)C(=O)Nc1cnc(N2CCC(C(=O)OC)CC2)c(C)c1.NN>>COC(=O)C1CCN(c2ncc(NC(=O)C(=O)NN)cc2C)CC1 -US20140170715A1,9,Oc1cccc2ccccc12>>c1ccc2ccccc2c1 -US20110105509A1,7,COC(=O)c1ccc(=O)n(Cc2ccc(F)cc2F)n1>>O=c1ccc(CO)nn1Cc1ccc(F)cc1F -US08546427B2,2,CC1(C)CC(c2ccccc2N)Nc2ccc(Cl)cc21.O=S(=O)(Cl)c1ccccc1F>>CC1(C)CC(c2ccccc2NS(=O)(=O)c2ccccc2F)Nc2ccc(Cl)cc21 -US20120065191A1,4,C#Cc1ccccc1.C[Si](C)(C)N=[N+]=[N-]>>c1ccc(-c2c[nH]nn2)cc1 -US07229987B2,1,Oc1ccc(-c2nc(CCl)cs2)cc1.SCCOc1ccccc1>>Oc1ccc(-c2nc(CSCCOc3ccccc3)cs2)cc1 -US20150005279A1,6,CC(C)(C)OC(=O)N1CCCC(c2ccc(C(N)=O)c3[nH]ccc23)C1>>NC(=O)c1ccc(C2CCCNC2)c2cc[nH]c12 -US07462735B2,2,Nc1ccccc1C(=O)NCCCC(=O)O.O=C(Cl)c1cc([N+](=O)[O-])ccc1O>>O=C(O)CCCNC(=O)c1ccccc1NC(=O)c1cc([N+](=O)[O-])ccc1O -US08445674B2,6,CC(C)(C)OC(=O)N1CCC2(CC1)COC2>>C1CC2(CCN1)COC2 -US20060084676A1,1,CC1(c2ccc([N+](=O)[O-])cc2)C(=O)Nc2cc(Cl)ccc2C1=O.CN1CCNCC1>>CN1CCN(c2ccc3c(c2)NC(=O)C(C)(c2ccc([N+](=O)[O-])cc2)C3=O)CC1 -US20060025474A1,7,CCOC(=O)/C=C/c1ccc(C(CC)(CC)c2ccc(/C=C/C(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c2)cc1C>>CCOC(=O)CCc1ccc(C(CC)(CC)c2ccc(/C=C/C(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c2)cc1C -US08426540B2,1,Nc1ccccc1O.O=Cc1ccc(-c2ccccc2C(F)(F)F)o1>>Oc1ccccc1N=Cc1ccc(-c2ccccc2C(F)(F)F)o1 -US20090291942A1,1,C1CCNCC1.CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(=O)CCCCCl)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(=O)CCCCN2CCCCC2)cc1 -US20120101136A1,6,CCOC(=O)COc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c(Cl)c1>>CC(C)Oc1ccc(-c2nc(-c3ccc(OCC(=O)O)cc3Cl)no2)cc1C#N -US20140275086A1,1,Cn1cnc(S(=O)(=O)N2C[C@@H](N)[C@H](c3ccc(F)cc3)C2)c1.O=Cc1ccccc1>>Cn1cnc(S(=O)(=O)N2C[C@@H](NCc3ccccc3)[C@H](c3ccc(F)cc3)C2)c1 -US08034812B2,1,CN.O=C(Nc1cccc(Oc2ccc3nc(Nc4ccnc(Cl)n4)cn3n2)c1)c1cccc(C(F)(F)F)c1>>CNc1nccc(Nc2cn3nc(Oc4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccc3n2)n1 -US20100267708A1,2,NCCCN1CCOCC1.O=C(O)C[C@@H]1CSC(c2cc3cc(Cl)cc(NC4CCCC4)c3[nH]2)=N1>>O=C(C[C@@H]1CSC(c2cc3cc(Cl)cc(NC4CCCC4)c3[nH]2)=N1)NCCCN1CCOCC1 -US05314880,1,CCOC(=O)c1ccc(CBr)cc1.c1ccc2[nH]cnc2c1>>CCOC(=O)c1ccc(Cn2cnc3ccccc32)cc1 -US08324252B2,7,N#Cc1cc(F)c(Nc2cc(C3CC3)[nH]n2)nc1N[C@@H](CO)c1ccc(F)cc1>>NCc1cc(F)c(Nc2cc(C3CC3)[nH]n2)nc1N[C@@H](CO)c1ccc(F)cc1 -US09034311B2,1,C[C@H](N)c1ccc(F)cn1.Clc1cc(Cl)nc(Cl)n1>>C[C@H](Nc1cc(Cl)nc(Cl)n1)c1ccc(F)cn1 -US06699861B1,1,C#CCN(Cc1cc2c(=O)n(C)c(COS(C)(=O)=O)nc2cc1Cl)c1ccc(C(=O)OC(C)(C)C)cc1.c1ccc(N2CCNCC2)cc1>>C#CCN(Cc1cc2c(=O)n(C)c(CN3CCN(c4ccccc4)CC3)nc2cc1Cl)c1ccc(C(=O)OC(C)(C)C)cc1 -US20040138462A1,6,CC(C)(C)OC(=O)N(CCc1ccc(S(=O)(=O)c2ccc(OCCO)cc2)cc1)C[C@H](O)c1cccc(Cl)c1>>O=S(=O)(c1ccc(CCNC[C@H](O)c2cccc(Cl)c2)cc1)c1ccc(OCCO)cc1 -US08569535B2,6,C#CCOc1c(C)cccc1C(=O)NC1(C(=O)OCC)Cc2ccccc2C1>>C#CCOc1c(C)cccc1C(=O)NC1(C(=O)O)Cc2ccccc2C1 -US08491869B2,3,C#Cc1ccc(NC)c(F)c1.COc1ccc2nc(I)sc2c1>>CNc1ccc(C#Cc2nc3ccc(OC)cc3s2)cc1F -US09133224B2,7,CCOP(=O)(Cc1ccc([N+](=O)[O-])c(OC)c1)OCC>>CCOP(=O)(Cc1ccc(N)c(OC)c1)OCC -US20110009454A1,1,N#Cc1cccc(F)c1.Oc1ccc(Cl)cc1>>N#Cc1cccc(Oc2ccc(Cl)cc2)c1 -US05110940,6,COC(=O)[C@H](CC(C)C)NC(=O)C[C@H](O)C[C@H](O)C=CC(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnnn1C>>CC(C)C[C@H](NC(=O)C[C@H](O)C[C@H](O)C=CC(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnnn1C)C(=O)O -US07202245B2,2,Cc1cccc(C(=O)O)n1.O=c1[nH]nc2c(NC3CCNCC3)nc3ccc(F)cc3n12>>Cc1cccc(C(=O)N2CCC(Nc3nc4ccc(F)cc4n4c(=O)[nH]nc34)CC2)n1 -US05075513,7,COC(=O)C12OC1(Cc1ccc(Cl)cc1)CCC2(C)C>>CC1(C)CCC2(Cc3ccc(Cl)cc3)OC12CO -US05849735,2,Cc1occc1C(=O)Nc1ccc(C(=O)Cl)cn1.c1ccc2c(c1)CNc1ccccc1N2>>Cc1occc1C(=O)Nc1ccc(C(=O)N2Cc3ccccc3Nc3ccccc32)cn1 -US05593993,2,CC(C)c1ccnc(N)c1.S=C=NCCC1=CCCCC1>>CC(C)c1ccnc(NC(=S)NCCC2=CCCCC2)c1 -US20100210642A1,3,C#Cc1ccc(N)nc1.CCc1cc(-c2ccc(Cl)cc2)nc2c(I)cnn12>>CCc1cc(-c2ccc(Cl)cc2)nc2c(C#Cc3ccc(N)nc3)cnn12 -US04837316,2,NCCCOc1cccc(CC2CCCCCN2)c1.O=C(O)CCl>>O=C(CCl)NCCCOc1cccc(CC2CCCCCN2)c1 -US04076526,2,C=CO.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>C=COC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 -US08530470B2,2,C1COCCN1.C[C@@H]1CN(c2cc(=O)c3cc(C(=O)O)cc(C4CCCN4c4cc(F)cc(F)c4)c3o2)CCO1>>C[C@@H]1CN(c2cc(=O)c3cc(C(=O)N4CCOCC4)cc(C4CCCN4c4cc(F)cc(F)c4)c3o2)CCO1 -US08420855B2,7,CCNc1ccc([N+](=O)[O-])cc1C(=O)Nc1c(C)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C>>CCNc1ccc(N)cc1C(=O)Nc1c(C)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C -US05981541,3,COc1cc(C=O)c([N+](=O)[O-])cc1OC.O=C1CCc2cc(Cl)ccc2C1>>COc1cc(C=C2C(=O)CCc3cc(Cl)ccc32)c([N+](=O)[O-])cc1OC -US20070161577A1,1,C1CN2CCN1CC2.O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(OCc3ccc(CBr)cc3)cc2)N1c1ccc(F)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(OCc3ccc(C[N+]45CCN(CC4)CC5)cc3)cc2)N1c1ccc(F)cc1 -US08138168B1,6,CCOc1nc(-c2ccc(C[C@H](CC(=O)N3CCC[C@@H](c4nc5ccccc5n4CCCOC)C3)NC(=O)OC(C)(C)C)cc2)cs1>>CCOc1nc(-c2ccc(C[C@@H](N)CC(=O)N3CCC[C@@H](c4nc5ccccc5n4CCCOC)C3)cc2)cs1 -US20100144712A1,1,Brc1cccc(NCCCN2CCOCC2)n1.CI>>CN(CCCN1CCOCC1)c1cccc(Br)n1 -US20130045962A1,6,CN(C)C1CN(c2nc(Cl)nc(NNC(=O)[C@H](CC3CCCC3)CN(C=O)OC3CCCCO3)c2F)CC1(C)C>>CN(C)C1CN(c2nc(Cl)nc(NNC(=O)[C@H](CC3CCCC3)CN(O)C=O)c2F)CC1(C)C -US20060025432A1,1,Fc1cccc(CBr)c1F.Oc1cc(O)nc(S)n1>>Oc1cc(O)nc(SCc2cccc(F)c2F)n1 -US20070049632A1,1,CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccc(F)cc3F)c(=O)c12.CCI>>CCn1c2c(c(=O)n1-c1ccc(F)cc1F)[C@H]1CC[C@]2(C)C1(C)C -US20130030012A1,1,O=Cc1ccc(F)cc1.Oc1ccc(Cl)c(Cl)c1>>O=Cc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1 -US05798316,2,C1CCNNC1.COC(=O)C(C)Oc1cc(C)ccc1COc1ccc(N=C=S)c(F)c1>>COC(=O)C(C)Oc1cc(C)ccc1COc1ccc(NC(=S)N2CCCCN2)c(F)c1 -US20090264431A1,2,COC[C@H]1C[C@H](O)CN1C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>COC[C@H]1C[C@H](OS(C)(=O)=O)CN1C(=O)OC(C)(C)C -US20110124636A1,4,CC(N)=S.COC(=O)C(=O)C(Cl)c1ccc(F)c(F)c1>>COC(=O)c1nc(C)sc1-c1ccc(F)c(F)c1 -US08114873B2,3,O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1cccc(Br)c1.OB(O)c1ccccc1F>>O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1cccc(-c2ccccc2F)c1 -US09079853B2,1,CCCCBr.O=C1Nc2ccc(Cl)cc2C1=O>>CCCCN1C(=O)C(=O)c2cc(Cl)ccc21 -US04333759,2,CC1(C)c2cc(C#N)ccc2OC1O.O=C(Cl)CCl>>CC1(C)c2cc(C#N)ccc2OC1OC(=O)CCl -US04950678,4,NNc1c(Cl)cc([N+](=O)[O-])cc1Cl.O=C(CC(=O)C(F)(F)F)C(F)(F)F>>O=[N+]([O-])c1cc(Cl)c(-n2nc(C(F)(F)F)cc2C(F)(F)F)c(Cl)c1 -US20130296312A1,3,Clc1nc2c(Br)cccn2n1.OB(O)c1cc(C(F)(F)F)ccc1Cl>>FC(F)(F)c1ccc(Cl)c(-c2cccn3nc(Cl)nc23)c1 -US20150197529A1,1,CS(=O)(=O)OCc1cc(F)c(Br)cc1F.C[C@H]1CCC(c2ccccc2)S(=O)(=O)N1>>C[C@H]1CCC(c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(Br)cc1F -US07919502B2,2,NCc1cccnc1.O=C(O)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1>>O=C(NCc1cccnc1)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1 -US20070197618A1,1,Clc1nc2ccccc2[nH]1.NC(c1ccc(F)cc1)c1ccc(F)cc1>>Fc1ccc(C(Nc2nc3ccccc3[nH]2)c2ccc(F)cc2)cc1 -US07538101B2,1,CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCS(=O)(=O)CC4)[nH]c3cc2Br)CC1.OB(O)c1ccnc(Cl)c1>>CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCS(=O)(=O)CC4)n(-c4ccnc(Cl)c4)c3cc2Br)CC1 -US20060052315A1,3,Cc1ccsc1Br.O=Cc1ccc(B(O)O)cc1>>Cc1ccsc1-c1ccc(C=O)cc1 -US20140051679A1,6,CCOC(=O)C(c1ccccn1)C1CCCC1>>O=C(O)C(c1ccccn1)C1CCCC1 -US04810713,1,ClCCCBr.NS(=O)(=O)c1ccc(O)cc1>>NS(=O)(=O)c1ccc(OCCCCl)cc1 -US20060089375A1,2,CCn1ncc2c(Cl)c(C(=O)O)cnc21.CN>>CCn1ncc2c(Cl)c(C(=O)NC)cnc21 -US07709521B2,1,CC(=O)COc1ccc(S(C)(=O)=O)cc1.N#Cc1ccc(NN)cc1>>CC(COc1ccc(S(C)(=O)=O)cc1)=NNc1ccc(C#N)cc1 -US20050209284A1,1,CC(C)(O)CNc1ccc(NC(=O)CCCCl)cc1[N+](=O)[O-]>>CC(C)(O)CNc1ccc(N2CCCC2=O)cc1[N+](=O)[O-] -US20070004757A1,3,CC(=O)N1C(=O)Cc2ccc(F)cc21.CCOC(=O)CCc1cccc(C(=O)O)c1>>CCOC(=O)CCc1cccc(C(O)=C2C(=O)N(C(C)=O)c3cc(F)ccc32)c1 -US20040058965A1,6,CCOC(=O)CCc1ccc(OCc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)cc1OCC>>CCOc1cc(OCc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)ccc1CCC(=O)O -US06034078,1,CI.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1>>Cc1cc2c(s1)N(C)c1ccccc1N=C2N1CCN(C)CC1 -US20110046169A1,1,COc1cc2nccc(Cl)c2cc1OC.Nc1ccc(O)cc1>>COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC -US05866566,9,NC(=O)N1c2ccccc2CC(=O)c2ccccc21.NO>>NC(=O)N1c2ccccc2CC(=NO)c2ccccc21 -US20130096144A1,1,CC(C)(C)OC(=O)N[C@H](CO)CC1CCCCC1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)CN1C(=O)c2ccccc2C1=O -US05047518,1,CI.O[C@@H]1[C@H](OCc2ccccc2)[C@H]2CO[C@H](O2)[C@@H]1OCc1ccccc1>>CO[C@@H]1[C@H](OCc2ccccc2)[C@H]2CO[C@H](O2)[C@@H]1OCc1ccccc1 -US05624926,1,C=CCBr.COc1cc2ncnc(N3CCC(n4c(=O)[nH]c5ccc([N+](=O)[O-])cc5c4=O)CC3)c2cc1OC>>C=CCn1c(=O)n(C2CCN(c3ncnc4cc(OC)c(OC)cc34)CC2)c(=O)c2cc([N+](=O)[O-])ccc21 -US07148234B2,2,CC(=O)OC(C)=O.Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-n3c(N)nc4c(C)cc(C)nc43)cc2)cc1>>CC(=O)Nc1nc2c(C)cc(C)nc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 -US20070299071A1,7,CS(=O)(=O)c1ccc(C2=CCOCC2)c(C(=O)O)c1>>CS(=O)(=O)c1ccc(C2CCOCC2)c(C(=O)O)c1 -US20110039889A1,3,CC(C)Oc1ccc(-c2nc(-c3cccc4c(Br)nccc34)no2)cc1Cl.CCOC(=O)CCC[Zn]Br>>CCOC(=O)CCCc1nccc2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12 -US20050026931A1,1,CCS(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1F.CS(=O)(=O)N1CCNCC1>>CCS(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1N1CCN(S(C)(=O)=O)CC1 -US08362040B2,6,CC(C)(C)OC(=O)N1CC[C@H](c2cccc(-c3cccc(O)c3)c2)[C@@H](OCc2ccc3ccccc3c2)C1>>Oc1cccc(-c2cccc([C@H]3CCNC[C@@H]3OCc3ccc4ccccc4c3)c2)c1 -US20090042964A1,3,C#Cc1ccccc1.FCCc1cc(Br)ccc1OC(F)F>>FCCc1cc(C#Cc2ccccc2)ccc1OC(F)F -US20130035337A1,3,CB1OB(C)OB(C)O1.COc1cc(F)cc(Br)c1>>COc1cc(C)cc(F)c1 -US06476021B1,6,CC(=O)N1c2ccccc2-n2cc(Cc3cccnc3)c(=O)c3cccc1c32>>O=c1c(Cc2cccnc2)cn2c3c(cccc13)Nc1ccccc1-2 -US08476434B2,2,Nc1ccc([N+](=O)[O-])cc1F.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>O=[N+]([O-])c1ccc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(F)c1 -US07176231B2,3,CC(=O)Cl.O=C1Cc2ccccc2N1>>CC(=O)c1ccc2c(c1)CC(=O)N2 -US05958918,1,COc1ccc2ccc(S(=O)(=O)N[C@H]3CCN(Cc4cccc(C#N)c4)C3=O)cc2c1.COc1cccc(CBr)c1>>COc1cccc(CN([C@H]2CCN(Cc3cccc(C#N)c3)C2=O)S(=O)(=O)c2ccc3ccc(OC)cc3c2)c1 -US08178533B2,1,CN.O=C1CC(c2cc(F)cc(F)c2F)CN1Cc1cnc(Cl)s1>>CNc1ncc(CN2CC(c3cc(F)cc(F)c3F)CC2=O)s1 -US07872002B2,7,COc1ccc(-n2nc3c4ccc([N+](=O)[O-])cc4[nH]cc-3c2=O)cc1>>COc1ccc(-n2nc3c4ccc(N)cc4[nH]cc-3c2=O)cc1 -US20120115885A1,1,BrCC1CCOCC1.COc1ccc(Cn2c(=O)c(-c3cccs3)c(O)c3cc(Br)ccc32)cc1>>COc1ccc(Cn2c(=O)c(-c3cccs3)c(OCC3CCOCC3)c3cc(Br)ccc32)cc1 -US05322853,1,Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-].Oc1cccc(Cl)c1Cl>>Nc1cc(Oc2cccc(Cl)c2Cl)c(Cl)cc1[N+](=O)[O-] -US20040053977A1,1,CC(=O)c1ccccn1.NNc1ccccn1>>CC(=NNc1ccccn1)c1ccccn1 -US05223529,2,Cc1cccc(N=C=O)c1.NCC(=O)N(CC(=O)N1CCCC1)c1ccccc1>>Cc1cccc(NC(=O)NCC(=O)N(CC(=O)N2CCCC2)c2ccccc2)c1 -US20100256132A1,2,COC(=O)c1cc(OCCN2CCOCC2)nc(N2CCOCC2)n1.Cc1[nH]c2ccc(N)cc2c1C>>Cc1[nH]c2ccc(NC(=O)c3cc(OCCN4CCOCC4)nc(N4CCOCC4)n3)cc2c1C -US04117128,6,COc1ccc(S(=O)(=O)c2c(-c3ccccc3)oc3ccc(Cl)cc23)cc1>>O=S(=O)(c1ccc(O)cc1)c1c(-c2ccccc2)oc2ccc(Cl)cc12 -US20050272744A1,3,N#Cc1ccc(N2CCC(=O)CC2)cc1.[Mg+]Cc1ccccc1>>N#Cc1ccc(N2CCC(O)(Cc3ccccc3)CC2)cc1 -US04550107,1,CCN(CC)C[C@@H]1CCCN1.O=C1Nc2ccccc2N(C(=O)CCl)c2ccccc21>>CCN(CC)C[C@@H]1CCCN1CC(=O)N1c2ccccc2NC(=O)c2ccccc21 -US20140135319A1,7,Cc1cc(-c2cnc3c(NCCC(F)(F)F)nc(C#N)cn23)ccc1C(=O)NC1CC1>>Cc1cc(-c2cnc3c(NCCC(F)(F)F)nc(CN)cn23)ccc1C(=O)NC1CC1 -US20110065930A1,7,CCOC(=O)C1=C(N[C@@H](C)c2ccccc2)CCCC1>>CCOC(=O)[C@@H]1CCCC[C@@H]1N[C@@H](C)c1ccccc1 -US08978554B2,2,C=CC(=O)Cl.NCC(=O)O>>C=CC(=O)NCC(=O)O -US08426429B2,1,CCCN1Cc2cc(Oc3cccc(CN)c3)ccc2N=C1NC(=O)OC(C)(C)C.Cc1cc(C)c(C=O)c(C)c1>>CCCN1Cc2cc(Oc3cccc(CNCc4c(C)cc(C)cc4C)c3)ccc2N=C1NC(=O)OC(C)(C)C -US06391874B1,1,NCCS(N)(=O)=O.O=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1>>NS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1 -US06204264B1,2,CCCCCCCCCCCCCCCCCc1nc2cc(N)ccc2n1CCCN(C)C.O=C(Cl)c1ccccc1>>CCCCCCCCCCCCCCCCCc1nc2cc(NC(=O)c3ccccc3)ccc2n1CCCN(C)C -US06140317,1,O=[N+]([O-])c1ccc(-c2cc3c(Cl)ncnc3[nH]2)cc1.c1ccc2c(c1)CCN2>>O=[N+]([O-])c1ccc(-c2cc3c(N4CCc5ccccc54)ncnc3[nH]2)cc1 -US20050032786A1,8,O=C(OO)c1cccc(Cl)c1.O=c1nc(-c2cccc(SCCCc3ccccc3)n2)sc2ccccc12>>O=c1nc(-c2cccc(S(=O)CCCc3ccccc3)n2)sc2ccccc12 -US20040029857A1,3,O=C(Cl)Cc1cccc(Cl)c1.O=C(c1ccc[nH]1)C(Cl)(Cl)Cl>>O=C(Cc1cccc(Cl)c1)c1c[nH]c(C(=O)C(Cl)(Cl)Cl)c1 -US08404859B2,6,COC(=O)[C@H](CNC(=O)OC(C)(C)C)NC(=O)c1sc(C(=O)NCc2cccc(O)c2)cc1Cl>>COC(=O)[C@H](CN)NC(=O)c1sc(C(=O)NCc2cccc(O)c2)cc1Cl -US20020123632A1,3,CCC(CNc1cc(Br)c(S(=O)(=O)NCc2ccc(F)c(Cl)c2)cc1C(=O)O)c1ccccc1.Cc1ccc(B(O)O)cc1>>CCC(CNc1cc(-c2ccc(C)cc2)c(S(=O)(=O)NCc2ccc(F)c(Cl)c2)cc1C(=O)O)c1ccccc1 -US20030045560A1,6,CCCc1c(C(=O)NCc2ccc3cc(OCC(=O)OC)ccc3c2)cnn1-c1ccccc1>>CCCc1c(C(=O)NCc2ccc3cc(OCC(=O)O)ccc3c2)cnn1-c1ccccc1 -US04474779,1,C=C(C)C.CCC(C)(Br)C(=O)O>>CCC(C)(Br)C(=O)OC(C)(C)C -US20150005232A1,3,COC(=O)c1ccc(B(O)O)c(F)c1.FC(F)(F)c1cc(Br)c2cn[nH]c2c1>>COC(=O)c1ccc(-c2cc(C(F)(F)F)cc3[nH]ncc23)c(F)c1 -US20140322355A1,2,CC1CC(c2ccc(C#N)cc2)CCN1.CCc1nnc(-c2cc(C(=O)O)c(C)cc2C2CCC2)[nH]1>>CCc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3C)c(C)cc2C2CCC2)[nH]1 -US08426420B2,2,C[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)O.O=C(OC1CCC1)N1CCNCC1>>C[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)N1CCN(C(=O)OC2CCC2)CC1 -US20070260058A1,6,CCOc1cc(C)c(NC(=O)OC(C)(C)C)cc1C>>CCOc1cc(C)c(N)cc1C -US06248894B1,2,CCNCC.O=C(Cl)c1ccccc1Cl>>CCN(CC)C(=O)c1ccccc1Cl -US20150057311A1,1,BrCC1CC1.O=c1[nH]c2ccccc2c(=O)o1>>O=c1oc(=O)n(CC2CC2)c2ccccc12 -US20050101644A1,6,CC(C)(C)OC(=O)NC1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1>>NC1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1 -US20090131530A1,7,COc1ccc(C=O)cc1Oc1cccc(C#N)c1>>COc1ccc(CO)cc1Oc1cccc(C#N)c1 -US05117053,6,COC(=O)C1(Cl)C(C)(C)C1(Cl)Cl>>CC1(C)C(Cl)(Cl)C1(Cl)C(=O)O -US20130310333A1,1,CC1(C)O[C@@H]2[C@H](O1)[C@@H](CNCCCNC(=O)Nc1ccc(C(C)(C)C)cc1)O[C@H]2n1cnc2c(N)ncnc21.CC=O>>CCN(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21 -US06194406B1,1,CCOCCn1c(N2CCCNCC2)nc2ccccc21.COc1cc(C(=O)N2CCC(CCOS(C)(=O)=O)(c3ccc(F)cc3)C2)cc(OC)c1OC>>CCOCCn1c(N2CCCN(CCC3(c4ccc(F)cc4)CCN(C(=O)c4cc(OC)c(OC)c(OC)c4)C3)CC2)nc2ccccc21 -US04736037,3,O=C(Cl)c1cccnc1Cl.c1ccccc1>>O=C(c1ccccc1)c1cccnc1Cl -US05223539,1,CC(C)N(C(=O)c1ccc(Br)cc1)C1CCCCC1.COc1ccc(O)cc1>>COc1ccc(Oc2ccc(C(=O)N(C(C)C)C3CCCCC3)cc2)cc1 -US20140018533A1,3,CCOC(=O)C1=C(Nc2ccc(OCC(O)CO)cc2C)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(Nc2ccc(OCC(O)CO)cc2C)OC(=Cc2c[nH]c3ncccc23)C1=O -US05616579,6,CC(=O)SCCC(=O)NC/C=C\COc1cc(CN2CCCCC2)ccn1>>O=C(CCS)NC/C=C\COc1cc(CN2CCCCC2)ccn1 -US04788187,9,O=C(C1CC2C=CC=CC21OCCCCl)N1CCCCC1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCCOC12C=CC=CC1CC2C(=O)N1CCCCC1 -US20140357858A1,2,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=C(Cl)c1c(Br)ccc2c1OCO2>>O=C1CC(=O)N(c2ccc(NC(=O)c3c(Br)ccc4c3OCO4)cc2)c2ccc3ccccc3c2N1 -US20040186103A1,2,CC(C)C(=O)Cl.Cc1ccc(N)cc1Br>>Cc1ccc(NC(=O)C(C)C)cc1Br -US20140080822A1,6,CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)OCc1nccn1-2>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)OCc1nccn1-2 -US20070049593A1,6,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCCc1ccccc1-3>>O=C(O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCCc1ccccc1-3 -US06329405B1,7,CC(NC(c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1)c1ccc(F)c(F)c1F>>CC(NC(c1ccc(Cl)cc1)c1cccc(N)c1)c1ccc(F)c(F)c1F -US20150218109A1,2,CCOC(=O)CC(=O)NNc1ccc(OC)cc1>>COc1ccc(N2NC(=O)CC2=O)cc1 -US20150152108A1,1,FC(F)(F)C1CCNCC1.O=C(Nc1ccccn1)N1c2nc(Cl)ccc2N2CC[C@H]1C2>>O=C(Nc1ccccn1)N1c2nc(N3CCC(C(F)(F)F)CC3)ccc2N2CC[C@H]1C2 -US08710236B2,6,CN(c1ccc(C(=O)OC(C)(C)C)cc1)C(C(=O)N(c1ccccc1)c1ccc2cccc-2o1)c1ccc(C(C)(C)C)cc1>>CN(c1ccc(C(=O)O)cc1)C(C(=O)N(c1ccccc1)c1ccc2cccc-2o1)c1ccc(C(C)(C)C)cc1 -US20070015744A1,7,CC(C)(C)OC(=O)N1CCN(c2cccc(NCc3ccccc3)c2[N+](=O)[O-])CC1>>CC(C)(C)OC(=O)N1CCN(c2cccc(NCc3ccccc3)c2N)CC1 -US07208500B2,2,C1CNC1.O=C(O)c1cc2nccc(Cl)c2s1>>O=C(c1cc2nccc(Cl)c2s1)N1CCC1 -US20040259907A1,1,CN.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)oc21>>CNCc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2o1 -US20130116243A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3C(F)F)CO4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3C(F)F)CO4)cc2)CCC1 -US20120329784A1,1,Cc1cccc(N)c1.Clc1cc(Cl)ncn1>>Cc1cccc(Nc2cc(Cl)ncn2)c1 -US06965029B2,7,COC(=O)CCCCC(=O)CCO>>COC(=O)CCCC[C@H](O)CCO -US05736540,7,O=C(c1ccc([N+](=O)[O-])cc1Cl)N1Cc2ccnn2Cc2ccccc21>>Nc1ccc(C(=O)N2Cc3ccnn3Cc3ccccc32)c(Cl)c1 -US08288412B2,1,O=C1CCOCC1.O=c1[nH]c2cc(Cl)c(C(F)(F)F)cc2n1C1CCNCC1>>O=c1[nH]c2cc(Cl)c(C(F)(F)F)cc2n1C1CCN(C2CCOCC2)CC1 -US08604023B2,2,CC(=O)OCC(=O)Cl.CN1C(=O)C(Cc2ccc3ccccc3c2)N=C(c2ccc(N)nc2)c2cc(Cl)ccc21>>CC(=O)OCC(=O)Nc1ccc(C2=NC(Cc3ccc4ccccc4c3)C(=O)N(C)c3ccc(Cl)cc32)cn1 -US20080039476A1,2,CC(=O)OC(C)=O.Cc1ccc(CCN)s1>>CC(=O)NCCc1ccc(C)s1 -US20060160821A1,2,CC(C)N1CCC(N)CC1.Cc1ccccc1C(NC(=O)Nc1ccc(Cl)cc1)C(=O)O>>Cc1ccccc1C(NC(=O)Nc1ccc(Cl)cc1)C(=O)NC1CCN(C(C)C)CC1 -US06410539B1,6,CC(C)(C)OC(=O)[C@H](CCC(N)=O)NC(=O)c1ccc(NC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccccc1>>NC(=O)CC[C@H](NC(=O)c1ccc(NC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccccc1)C(=O)O -US20080032951A1,6,CCOC(=O)Cn1nc(C(=O)C(C)C)c2ccc(OC)cc21>>COc1ccc2c(C(=O)C(C)C)nn(CC(=O)O)c2c1 -US20040097503A1,1,COCc1cc(Cl)nc(-c2cccc(C)c2)n1.COc1ccc(Cl)c(N)c1>>COCc1cc(Nc2cc(OC)ccc2Cl)nc(-c2cccc(C)c2)n1 -US06949542B2,2,CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F.Cc1ccc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)nn1>>Cc1ccc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(N(C)C)cc3NC(=O)OC(C)(C)C)c2)nn1 -US08053440B2,7,Cc1cc(-c2nc3ccc([N+](=O)[O-])cc3c(=O)[nH]2)cc(C)c1O>>Cc1cc(-c2nc3ccc(N)cc3c(=O)[nH]2)cc(C)c1O -US20110071194A1,2,CCCC(=O)Cl.C[C@@H](N)[C@@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1>>CCCC(=O)N[C@@H](C)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1 -US04388463,1,CN1CC[C@]23CC(=O)CC[C@H]2[C@H]1Cc1cccc(O)c13.Clc1nnnn1-c1ccccc1>>CN1CC[C@]23CC(=O)CC[C@H]2[C@H]1Cc1cccc(Oc2nnnn2-c2ccccc2)c13 -US20070173498A1,2,COc1ccc(N)cc1OC.O=C([O-])c1ccc(COc2ccc3c(c2)CCC(CCN2CCCCC2)C3)cc1>>COc1ccc(NC(=O)c2ccc(COc3ccc4c(c3)CCC(CCN3CCCCC3)C4)cc2)cc1OC -US06660751B1,4,Cc1ccc(N)c(N)c1.O=C(O)C1CCNCC1>>Cc1ccc2[nH]c(C3CCNCC3)nc2c1 -US20090192138A1,1,CC#CCBr.Cn1c(=O)c2[nH]c(N3CCC[C@H](NC(=O)OC(C)(C)C)C3)c(C#N)c2n(C)c1=O>>CC#CCn1c(N2CCC[C@H](NC(=O)OC(C)(C)C)C2)c(C#N)c2c1c(=O)n(C)c(=O)n2C -US08859534B2,2,NC1CCN(c2ncccc2Cl)CC1.O=C([O-])c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1>>O=C(NC1CCN(c2ncccc2Cl)CC1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 -US08791102B2,2,CCN(CC)C1CCN(CC(=O)O)C1.N[C@@H](COCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1>>CCN(CC)C1CCN(CC(=O)N[C@@H](COCc2ccccc2)C(=O)Nc2ccc(Oc3ccc(F)cc3)cc2)C1 -US06498172B1,1,CC(C)(C)OC(=O)COc1cccc(CN)c1.O=Cc1ccc(-c2cccnc2)cc1>>CC(C)(C)OC(=O)COc1cccc(CNCc2ccc(-c3cccnc3)cc2)c1 -US06130187,2,CCN.Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c3cc(C(=O)O)oc23)c1=O>>CCNC(=O)c1cc2c(Cl)ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c2o1 -US20020193599A1,2,CCO.O=C(O)C1(c2ccccc2)CCNCC1>>CCOC(=O)C1(c2ccccc2)CCNCC1 -US08367844B2,6,CN(C(=O)c1cccc(C2CCN(C(=O)OC(C)(C)C)CC2)n1)C1CCCc2ccccc21>>CN(C(=O)c1cccc(C2CCNCC2)n1)C1CCCc2ccccc21 -US08426585B2,1,CS(=O)(=O)OCCCC1(O)CC1.NC(=O)C1(C(=O)N(c2ccccc2)c2ccc(Oc3ccnc4cc(O)ccc34)c(F)c2)CC1>>NC(=O)C1(C(=O)N(c2ccccc2)c2ccc(Oc3ccnc4cc(OCCCC5(O)CC5)ccc34)c(F)c2)CC1 -US20140315857A1,9,NO.O=Cc1ccnc2ncccc12>>ON=Cc1ccnc2ncccc12 -US20110144334A1,3,CN(C)C=O.CON=CNC(=O)c1ccc(Br)cc1C>>CON=CNC(=O)c1ccc(C=O)cc1C -US07998959B2,1,COC(=O)C1(CC=O)CCCN1C(=O)OC(C)(C)C.Nc1ccccc1Cl>>COC(=O)C1(CCNc2ccccc2Cl)CCCN1C(=O)OC(C)(C)C -US20080027049A1,2,Nc1ccc2oc3c(c2c1)CCCCCC3.O=C(O)Cc1ccncc1>>O=C(Cc1ccncc1)Nc1ccc2oc3c(c2c1)CCCCCC3 -US20080255124A1,1,CCCI.N#Cc1ccc(NCCc2ccccc2)cc1C(F)(F)F>>CCCN(CCc1ccccc1)c1ccc(C#N)c(C(F)(F)F)c1 -US20050014812A1,1,Cc1nc2c(C)cc(Br)cc2[nH]1.FC(F)(F)c1cnc(CCl)c(Cl)c1>>Cc1cc(Br)cc2c1nc(C)n2Cc1ncc(C(F)(F)F)cc1Cl -US20120053053A1,9,COc1c(Cl)ccc(Br)c1F.N#C[Cu]>>COc1c(Cl)ccc(C#N)c1F -US07432284B2,6,CCCCC12CC(=O)C=C1c1ccc(OC)cc1C2>>CCCCC12CC(=O)C=C1c1ccc(O)cc1C2 -US20040235921A1,6,CCOC(=O)[C@H]1COc2cc(CCNC[C@H](O)COc3ccc(OCc4ccccc4)cc3OC)ccc2O1>>CCOC(=O)[C@H]1COc2cc(CCNC[C@H](O)COc3ccc(O)cc3OC)ccc2O1 -US08623866B2,2,CCOC(=O)c1nc(NCCOC)ncc1Nc1cncnc1.CNC(=O)c1nn(C)cc1N>>CNC(=O)c1nn(C)cc1NC(=O)c1nc(NCCOC)ncc1Nc1cncnc1 -US06455587B1,2,Cc1ccc(S(=O)(=O)Cl)cc1.NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>Cc1ccc(S(=O)(=O)NCCCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1 -US08546387B2,2,Cc1nc2nccc(Oc3ccc(N)c(F)c3)c2[nH]c1=O.O=C=Nc1cc(C(F)(F)F)ccc1F>>Cc1nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c(F)c3)c2[nH]c1=O -US20120316165A1,6,CC(C)(C)OC(=O)N1CCO[C@H](c2ccc(NC(=O)Nc3cccc(C#N)c3)c(F)c2)C1>>N#Cc1cccc(NC(=O)Nc2ccc([C@@H]3CNCCO3)cc2F)c1 -US08153647B2,2,CCCNC(=N)N.CCOC(=O)CC(C)(C)c1ccc(-c2ccc(C(=O)N3CCN(C)CC3)cc2)c(OCCCOC)c1>>CCCNC(=N)NC(=O)CC(C)(C)c1ccc(-c2ccc(C(=O)N3CCN(C)CC3)cc2)c(OCCCOC)c1 -US04452799,1,C1CNCCN1.Clc1noc2ccccc12>>c1ccc2c(N3CCNCC3)noc2c1 -US20150232452A1,3,CC(C)(C)c1nc(-c2ccnc(N)n2)c(Br)s1.CC1(C)OB(c2cccc(N)c2)OC1(C)C>>CC(C)(C)c1nc(-c2ccnc(N)n2)c(-c2cccc(N)c2)s1 -US20140066457A1,4,C=C(CC(=O)O)C(=O)O.NC1CCCCC1>>O=C(O)C1CC(=O)N(C2CCCCC2)C1 -US20040077654A1,2,CCOC(=O)c1ccc(N)cc1.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 -US20110166116A1,1,CC(C)OC(=O)N1CCC(ON=C2CCNCC2)CC1.O=Cc1cnc(Cl)c(F)c1>>CC(C)OC(=O)N1CCC(ON=C2CCN(c3ncc(C=O)cc3F)CC2)CC1 -US05994563,2,O=C(Cl)c1ccccc1.O=Cc1ccc(O)c([N+](=O)[O-])c1>>O=Cc1ccc(OC(=O)c2ccccc2)c([N+](=O)[O-])c1 -US20040044058A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H](N)C(=O)O>>C[C@H](NC(=O)OC(C)(C)C)C(=O)O -US04514045,1,CC(C)=CCCC(C)CC=O.Nc1cccc2ccccc12>>CC(C)=CCCC(C)CCNc1cccc2ccccc12 -US04501746,2,CC(=O)Cl.Clc1ccc(NCc2cccnc2)cc1>>CC(=O)N(Cc1cccnc1)c1ccc(Cl)cc1 -US05366957,9,CC(C)(C)OC(=O)C(C(=O)c1ccc(S(C)(=O)=O)cc1F)C(=O)C1CC1>>CS(=O)(=O)c1ccc(C(=O)CC(=O)C2CC2)c(F)c1 -US05672596,2,CC(C)(NC(=O)OCc1ccccc1)C(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3CN)cc2)C1=O.CC(C)N=C=O>>CC(C)NC(=O)NCc1ccccc1-c1ccc(CN2C(=O)[C@H](NC(=O)C(C)(C)NC(=O)OCc3ccccc3)CCc3ccccc32)cc1 -US04143146,10,CC=CN1C(=O)CCC1=O.Cl>>CCC(Cl)N1C(=O)CCC1=O -US07179941B2,7,COc1ccc([N+](=O)[O-])cc1NC(=O)NC(=O)c1cc(F)c(F)cc1Cl>>COc1ccc(N)cc1NC(=O)NC(=O)c1cc(F)c(F)cc1Cl -US05512433,1,Cn1c(=O)c2[nH]c(Br)nc2n(C)c1=O.NCCCCCO>>Cn1c(=O)c2[nH]c(NCCCCCO)nc2n(C)c1=O -US20120022118A1,4,C#Cc1ccc(OC)cc1.COc1cc(N=[N+]=[N-])cc(OC)c1OC>>COc1ccc(-c2cnnn2-c2cc(OC)c(OC)c(OC)c2)cc1 -US20100009969A1,1,CC1CCCN1.CCNC(=O)N1CCc2nc(-c3ccc(OCCCCl)cc3)sc2C1>>CCNC(=O)N1CCc2nc(-c3ccc(OCCCN4CCCC4C)cc3)sc2C1 -US20100137397A1,6,COC(=O)C(CC1CC1)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1>>O=C(N[C@@H]1Cc2ccccc2[C@H]1C(CC1CC1)C(=O)O)c1cc2sc(Cl)c(Cl)c2[nH]1 -US20120245359A1,1,COc1cccc(-c2cc(F)c(N)c(F)c2)c1.O=C(O)c1cccnc1Cl>>COc1cccc(-c2cc(F)c(Nc3ncccc3C(=O)O)c(F)c2)c1 -US20150126484A1,1,C1CCNCC1.O=C(CBr)c1cccc(F)c1>>O=C(CN1CCCCC1)c1cccc(F)c1 -US20150038528A1,2,CC(=O)OC(C)=O.N#Cc1nc(C(=O)NCC[C@@H](N)C(=O)O)c(O)c2ccc(Oc3ccccc3)cc12>>CC(=O)N[C@H](CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(=O)O -US09079866B2,3,Brc1cccnc1OC1CCNCC1.CC1(C)OB(c2ccc(-c3cnc(N)nc3)c(F)c2)OC1(C)C>>Nc1ncc(-c2ccc(-c3cccnc3OC3CCNCC3)cc2F)cn1 -US20140011881A1,2,C#Cc1cc(CN)cc(F)c1NS(C)(=O)=O.CCCc1cc(C(F)(F)F)ccc1C=CC(=O)O>>C#Cc1cc(CNC(=O)C=Cc2ccc(C(F)(F)F)cc2CCC)cc(F)c1NS(C)(=O)=O -US20120226035A1,1,O=C(N(Cc1cc2c(cn1)OCCO2)CC1CCCNC1)C(F)(F)F.O=CCn1c(=O)ccc2ncc(F)cc21>>O=C(N(Cc1cc2c(cn1)OCCO2)CC1CCCN(CCn2c(=O)ccc3ncc(F)cc32)C1)C(F)(F)F -US06107301,2,CCN(c1nc(C)cc(CO)n1)c1ccc(C(C)C)cc1Br.CS(=O)(=O)Cl>>CCN(c1nc(C)cc(COS(C)(=O)=O)n1)c1ccc(C(C)C)cc1Br -US20100305092A1,4,N#Cc1ccc(N)c(N)c1.O=CO>>N#Cc1ccc2[nH]cnc2c1 -US20100004221A1,6,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(-c3ccc(-c4ccc(F)cc4)cc3C(F)(F)F)n2CCS1>>CC1(CO)Cc2nnc(-c3ccc(-c4ccc(F)cc4)cc3C(F)(F)F)n2CCS1 -US20150210702A1,1,CC(C)(C)OC(=O)N1CC(N)C1.COc1cc(F)ccc1[N+](=O)[O-]>>COc1cc(NC2CN(C(=O)OC(C)(C)C)C2)ccc1[N+](=O)[O-] -US20110130417A1,1,O=C(O)CBr.O=C1N(c2ccc(C3CC3)cc2)CCC12CCNCC2>>O=C(O)CN1CCC2(CC1)CCN(c1ccc(C3CC3)cc1)C2=O -US20090176786A1,2,CN(C(=O)Cl)c1ccc(SC(F)(F)F)cc1F.COC(CN)OC>>COC(CNC(=O)N(C)c1ccc(SC(F)(F)F)cc1F)OC -US08008298B2,2,CC1(C(=O)c2c[nH]c3ncc(-c4cccc(N5CCNCC5)c4)nc23)CCCCC1.N#CCC(=O)O>>CC1(C(=O)c2c[nH]c3ncc(-c4cccc(N5CCN(C(=O)CC#N)CC5)c4)nc23)CCCCC1 -US07709471B2,2,CN1CCC(N)CC1.Nc1nc(C(=O)O)cs1>>CN1CCC(NC(=O)c2csc(N)n2)CC1 -US06407262B1,6,CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H](C(=O)OCc2ccccc2)C[C@@H]2CCC[C@@H]21>>CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCC[C@@H]21 -US20150038574A1,1,CC1=C(C=O)C(C)(C)CCC1.Nc1cccc(C(F)(F)F)c1>>CC1=C(CNc2cccc(C(F)(F)F)c2)C(C)(C)CCC1 -US08822471B2,1,Cc1cnc(Cl)nc1.OC1CCNCC1>>Cc1cnc(N2CCC(O)CC2)nc1 -US20120202794A1,2,CC=C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)c1cc(-c2ccc(F)cc2)on1>>C/C=C/[C@H]1CN(C(=O)c2cc(-c3ccc(F)cc3)on2)[C@@H](CC(C)C)C(=O)N1 -US04985422,4,ON=C1CCc2oc3ccccc3c21>>O=C1NCCc2oc3ccccc3c21 -US06184225B2,6,COC(=O)Oc1cc(Nc2ncnc3cc(OCc4ccccc4)c(OC)cc23)c(F)cc1C>>COC(=O)Oc1cc(Nc2ncnc3cc(O)c(OC)cc23)c(F)cc1C -US05385930,6,CCOC(=O)CCCOc1cccc2c1SCCC2>>O=C(O)CCCOc1cccc2c1SCCC2 -US20100190852A1,1,CCOC(=O)c1ccc(CCNC)cc1.COC(=O)C(C#N)(CCCBr)c1ccc(OC)c(OC)c1>>CCOC(=O)c1ccc(CCN(C)CCCC(C#N)(C(=O)OC)c2ccc(OC)c(OC)c2)cc1 -US20140315022A1,2,C=CCNCC=C.CCCCCC(=O)Cl>>C=CCN(CC=C)C(=O)CCCCC -US06951879B2,1,BrCCCCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1.C1COCCN1>>Brc1ccc(-c2nsc3cc(OCCCCN4CCOCC4)ccc23)cc1 -US20150152088A1,2,CN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1.Cc1ccc(C(=O)Cl)cc1I>>Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1I -US20150246922A1,3,O=C1NCCCn2c1cc1cc(F)cc(Br)c12.OB(O)c1ccncc1>>O=C1NCCCn2c1cc1cc(F)cc(-c3ccncc3)c12 -US20090275609A1,2,N#Cc1ccc(CN2CCC(N)CC2)cc1.O=C(O)c1cnc(Br)s1>>N#Cc1ccc(CN2CCC(NC(=O)c3cnc(Br)s3)CC2)cc1 -US07034039B2,6,CCOC(=O)c1sc(-c2ccc3c(=O)n(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c4ccccc4)c3c2)nc1C>>Cc1nc(-c2ccc3c(=O)n(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c4ccccc4)c3c2)sc1C(=O)O -US08563565B2,1,COc1nc(C)cc(C)c1-c1cc(F)c(-c2c(C(N)=O)cnn2C2CCOCC2)cc1F>>COc1nc(C)cc(C)c1-c1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1F -US03976681,6,CCC1(CC)C(=O)c2cc(OC)c(C)c(C)c2C1=O>>CCC1(CC)C(=O)c2cc(O)c(C)c(C)c2C1=O -US07410963B2,3,COc1cc2c(cc1Br)C(c1cccc(C#N)c1)=NCC(=O)N2C.OB(O)c1ccccc1>>COc1cc2c(cc1-c1ccccc1)C(c1cccc(C#N)c1)=NCC(=O)N2C -US08648200B2,6,CCOC(=O)c1cc(CNC(=O)C(C)C)cnc1C(F)F>>CC(C)C(=O)NCc1cnc(C(F)F)c(C(=O)O)c1 -US20070213337A1,6,CC(C)(C)OC(=O)N1CCN2C(=O)c3c(cc(Nc4ccccc4)cc3C(F)(F)F)[C@@H]2C1>>O=C1c2c(cc(Nc3ccccc3)cc2C(F)(F)F)[C@@H]2CNCCN12 -US20140296230A1,3,CON(C)C(=O)c1ccccc1NC(=O)OC(C)(C)C.[Mg+]c1ccc(Cl)cc1>>CC(C)(C)OC(=O)Nc1ccccc1C(=O)c1ccc(Cl)cc1 -US20090325916A1,3,O=C1CCCc2cc(OS(=O)(=O)C(F)(F)F)ccc21.OB(O)c1ccc(F)c(Cl)c1>>O=C1CCCc2cc(-c3ccc(F)c(Cl)c3)ccc21 -US20100256126A1,6,CCOC(=O)C1(CC2CC2)CCN(C(=O)c2ccc(-c3ccc(F)cc3)cc2)CC1>>O=C(c1ccc(-c2ccc(F)cc2)cc1)N1CCC(CC2CC2)(C(=O)O)CC1 -US05728686,1,CCCCn1cnc2c1c(=O)[nH]c(=O)n2CCCC.CCOP(=O)(CCCBr)OCC>>CCCCn1cnc2c1c(=O)n(CCCP(=O)(OCC)OCC)c(=O)n2CCCC -US04544657,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccccc1N1CCNCC1>>COc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1 -US07803825B2,4,NC(=S)c1ccc(Cn2cnc3ccccc32)cc1.O=C(CCl)CCl>>ClCc1csc(-c2ccc(Cn3cnc4ccccc43)cc2)n1 -US20060183909A1,7,COC(=O)c1cc(O)c2cc([N+](=O)[O-])cc(OC)c2n1>>COC(=O)c1cc(O)c2cc(N)cc(OC)c2n1 -US20110224136A1,2,CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(-c4ccc(C(=O)O)cc4)cc3)o2)C1.COc1ccccc1N>>COc1ccccc1NC(=O)c1ccc(-c2ccc(NC(=O)c3oc(N4CCCC(C)C4)nc3C(F)(F)F)cc2)cc1 -US06284757B1,1,Clc1cncc(Cl)n1.Fc1ccc(OCC2CC3CNCCN3C2)cc1>>Fc1ccc(OC[C@H]2C[C@H]3CN(c4cncc(Cl)n4)CCN3C2)cc1 -US08710046B2,1,COC(=O)c1cccc2[nH]nc(C=O)c12.NCC12CCN(CC1)CC2>>COC(=O)c1cccc2[nH]nc(CNCC34CCN(CC3)CC4)c12 -US20100004256A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1nc(O)c2c(n1)-c1ccoc1CCC2>>Cc1ccc(S(=O)(=O)Oc2nc(N)nc3c2CCCc2occc2-3)cc1 -US20120029187A1,1,CC1OCCNC1=O.O=S(=O)(Nc1ccccc1CO)C(F)(F)F>>CC1OCCN(Cc2ccccc2NS(=O)(=O)C(F)(F)F)C1=O -US20050113370A1,6,CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(Nc3cccnc3)cc21>>c1ccc(-c2n[nH]c3cc(Nc4cccnc4)ccc23)cc1 -US07429608B2,1,Clc1nc2cc(Br)ccc2[nH]1.Nc1cccc2c1CC(O)CC2>>OC1CCc2cccc(Nc3nc4cc(Br)ccc4[nH]3)c2C1 -US09084794B2,1,NC(=O)C(O)c1c(F)cc(Br)cc1F.O=C1COC2(CCNCC2)CN1C1CC1>>NC(=O)C(c1c(F)cc(Br)cc1F)N1CCC2(CC1)CN(C1CC1)C(=O)CO2 -US20080194629A1,2,CCNCC(C)C.COCCCCC1(CNC(=O)[C@H]2C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21>>CCN(CC(C)C)C(=O)[C@@H]1C[C@H](C(=O)NCC2(CCCCOC)c3ccccc3Oc3ccccc32)CN(C(=O)OC(C)(C)C)C1 -US07994162B2,1,CC(C)(C)OC(=O)N[C@H]1CCc2ccccc2NC1=O.CI>>CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CCc2ccccc21 -US08327467B2,6,CC(C)Oc1ccccc1-c1ccc(C(=O)OC(C)(C)C)c(Nc2ccc(F)cc2)c1>>CC(C)Oc1ccccc1-c1ccc(C(=O)O)c(Nc2ccc(F)cc2)c1 -US07476677B2,2,Cn1cnc(-c2cccc(N)c2)c1-c1cc2c(N)ncnc2s1.O=C=Nc1ccccc1F>>Cn1cnc(-c2cccc(NC(=O)Nc3ccccc3F)c2)c1-c1cc2c(N)ncnc2s1 -US20110306646A1,1,NC1CC1.O=C1CCCCC1c1ccccc1>>c1ccc([C@H]2CCCC[C@H]2NC2CC2)cc1 -US20110306646A1,1,NC1CC1.O=C1CCCCC1c1ccccc1>>c1ccc([C@@H]2CCCC[C@H]2NC2CC2)cc1 -US06806267B1,1,CCOC(=O)C(Br)c1ccc(C)cc1.Oc1ccccc1-n1cccc1>>CCOC(=O)C(Oc1ccccc1-n1cccc1)c1ccc(C)cc1 -US05646283,3,CCCC[Sn](CCCC)(CCCC)c1ccncc1.O=C1CCCc2cc(OS(=O)(=O)C(F)(F)F)ccc21>>O=C1CCCc2cc(-c3ccncc3)ccc21 -US20140213448A1,2,CC(C)(C)C(=O)Cl.CCNC(=O)N(C)c1cn(-c2cccnc2)nc1Cl>>CCN(C(=O)N(C)c1cn(-c2cccnc2)nc1Cl)C(=O)C(C)(C)C -US06548494B1,6,COC(=O)CCC/C(C)=C/c1cccc2c1NCCNC2=O>>C/C(=C\c1cccc2c1NCCNC2=O)CCCC(=O)O -US20130158031A1,3,Brc1cccc(Br)n1.OB(O)C1CC1>>Brc1cccc(C2CC2)n1 -US08779132B2,2,O=C(Cl)OCc1ccccc1.OCc1ccc2c(c1)CNC2>>O=C(OCc1ccccc1)N1Cc2ccc(CO)cc2C1 -US04678855,7,NS(=O)(=O)c1ccc(S(=O)(=O)CCCO)c([N+](=O)[O-])c1>>Nc1cc(S(N)(=O)=O)ccc1S(=O)(=O)CCCO -US20030207916A1,7,O=C1CCc2c(O)cccc21>>Oc1cccc2c1CCC2 -US04388463,1,Clc1nnnn1-c1ccccc1.O=CN1CC[C@]23CC(=O)CC[C@H]2[C@H]1Cc1cc(O)cc(O)c13>>O=CN1CC[C@]23CC(=O)CC[C@H]2[C@H]1Cc1cc(Oc2nnnn2-c2ccccc2)cc(O)c13 -US20120071512A1,3,Brc1cncc(Br)c1.Cc1c(B2OC(C)(C)C(C)(C)O2)ccc2c1CC(=O)N2C>>Cc1c(-c2cncc(Br)c2)ccc2c1CC(=O)N2C -US20080113981A1,6,O=c1ccc2c([C@@H](O)CNCCc3ccc(Oc4cccc(-c5ccccc5)c4)cc3)ccc(OCc3ccccc3)c2[nH]1>>O=c1ccc2c([C@@H](O)CNCCc3ccc(Oc4cccc(-c5ccccc5)c4)cc3)ccc(O)c2[nH]1 -US08669255B2,2,NC1CCN2CCN(c3cccc(C(F)(F)F)n3)CC12.O=S(=O)(Cl)Cc1ccc(Cl)cc1>>O=S(=O)(Cc1ccc(Cl)cc1)N[C@@H]1CCN2CCN(c3cccc(C(F)(F)F)n3)C[C@@H]12 -US20040242572A1,2,NCCc1ccc(CN2CCCC2)cc1F.O=C(O)c1ccc(-c2ccc(Cl)cc2)cc1>>O=C(NCCc1ccc(CN2CCCC2)cc1F)c1ccc(-c2ccc(Cl)cc2)cc1 -US05117057,2,CC(C)(C)N(N)C(=O)c1ccccc1.Cc1cccc(C(=O)Cl)c1>>Cc1cccc(C(=O)NN(C(=O)c2ccccc2)C(C)(C)C)c1 -US04751232,7,CC(=O)Nc1c(C)ccc([N+](=O)[O-])c1C>>CC(=O)Nc1c(C)ccc(N)c1C -US06579881B2,6,CC(=O)N1CC[C@@H](N2CCc3ccccc32)[C@H](CO)C1>>OC[C@@H]1CNCC[C@H]1N1CCc2ccccc21 -US07521454B2,1,CCCCOc1nc(N)c2ncn(Cc3ccc(Cl)nc3)c2n1.CO>>CCCCOc1nc(N)c2ncn(Cc3ccc(OC)nc3)c2n1 -US20110009428A1,1,N#CCBr.Nc1ccc2c(Sc3ccccc3[N+](=O)[O-])cn(Cc3cc(F)cc(F)c3)c2c1>>N#CCNc1ccc2c(Sc3ccccc3[N+](=O)[O-])cn(Cc3cc(F)cc(F)c3)c2c1 -US08470841B2,1,CC(=O)NC(C)CCc1ccc(Oc2ccc(F)nc2)cc1.OCC1CC1>>CC(=O)NC(C)CCc1ccc(Oc2ccc(OCC3CC3)nc2)cc1 -US07727988B2,6,O=C(c1ccccc1)n1c(=O)c(I)cn(CCCN2CC3CC3(c3ccc(Cl)cc3)C2)c1=O>>O=c1[nH]c(=O)n(CCCN2CC3CC3(c3ccc(Cl)cc3)C2)cc1I -US20110039852A1,2,CCNCc1cc(-c2ccc3ncccc3c2)ccc1-c1cc(CC(=O)OCC)ccc1OC.O=C=NCc1ccccc1>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(-c3ccc4ncccc4c3)cc2CN(CC)C(=O)NCc2ccccc2)c1 -US07105671B2,2,COC(=O)C(CC1CCCC1(F)F)c1ccc(Cl)c(Cl)c1.Nc1nccs1>>O=C(Nc1nccs1)C(CC1CCCC1(F)F)c1ccc(Cl)c(Cl)c1 -US20040242884A1,8,CN(CCO)C(c1ccccc1)(c1ccccc1)c1ccccc1>>CN(CC=O)C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20040192686A1,1,[N-]=[N+]=NCCCN.[O-][n+]1nc(Cl)nc2ccccc21>>[N-]=[N+]=NCCCNc1nc2ccccc2[n+]([O-])n1 -US05639915,2,CC1CCCC1O.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC2CCCC2C)cc1 -US08513424B2,1,CS(=O)(=O)c1ccc(F)c(F)c1.O=c1cc(OCc2ccccc2)cc[nH]1>>CS(=O)(=O)c1ccc(-n2ccc(OCc3ccccc3)cc2=O)c(F)c1 -US07956216B2,2,CCCN.O=C(O)c1cccc(I)c1>>CCCNC(=O)c1cccc(I)c1 -US05965741,10,CCOC(=O)c1cnc(C)s1.O=C1CCC(=O)N1Br>>CCOC(=O)c1cnc(CBr)s1 -US05635510,6,CC(C)(C)OC(=O)N1CCC(C(N)=O)(c2ccccn2)CC1>>NC(=O)C1(c2ccccn2)CCNCC1 -US05274125,7,C/C(=C\c1ccc(C(C)(C)C)cc1)CO>>C[C@@H](CO)Cc1ccc(C(C)(C)C)cc1 -US20050250836A1,10,C=Cc1cn(C)c2cc(-c3ccccc3Cl)c3c(c12)C(=O)NC3=O.O>>Cn1cc(CCO)c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O -US07452992B2,6,CC(C)(C)C(=O)N1CCC(CCO[Si](C)(C)C(C)(C)C)(c2ccccc2)OC1>>CC(C)(C)C(=O)N1CCC(CCO)(c2ccccc2)OC1 -US20120172369A1,3,CCOC(=O)C1CCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.Nc1ccc(Br)nc1>>CCOC(=O)C1CCC(Oc2ccc(-c3ccc(N)cn3)cn2)CC1 -US04797400,1,COc1cc(CN2CCNCC2)cc(OC)c1OC.COc1ccc(OC(=O)CCl)cc1>>COc1ccc(OC(=O)CN2CCN(Cc3cc(OC)c(OC)c(OC)c3)CC2)cc1 -US20130023541A1,1,CCc1ccc(C=O)s1.CN[C@H]1CCN(c2ncccc2C(=O)OC(C)C)C1>>CCc1ccc(CN(C)[C@H]2CCN(c3ncccc3C(=O)OC(C)C)C2)s1 -US05192789,7,Cn1c2c(c3cc(O)ccc31)CCC2=NCc1ccccc1>>Cn1c2c(c3cc(O)ccc31)CCC2NCc1ccccc1 -US20090215857A1,7,CCOC(=O)c1ncccc1-c1cc(F)ccc1F>>OCc1ncccc1-c1cc(F)ccc1F -US20080214394A1,3,O=S(=O)(NCc1ccnc2ccccc12)c1ccc(Br)s1.OB(O)c1ccc(Cl)cc1>>O=S(=O)(NCc1ccnc2ccccc12)c1ccc(-c2ccc(Cl)cc2)s1 -US20070203129A1,6,CCOC(=O)c1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C>>Cc1c(C(=O)O)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1 -US20040009967A1,3,N#CCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCCN(Cc2ccccc2)C1>>N#CCCC=C1CCCN(Cc2ccccc2)C1 -US20120108577A1,2,CC1CC(N(Cc2ccccc2)Cc2ccccc2)CCN1CCO.CS(=O)(=O)Cl>>CC1CC(N(Cc2ccccc2)Cc2ccccc2)CCN1CCOS(C)(=O)=O -US20150031674A1,1,CC(C)(C)OC(=O)N1CC(I)C1.CCOC(=O)CS>>CCOC(=O)CSC1CN(C(=O)OC(C)(C)C)C1 -US20100105655A1,1,COc1cc(C(CO)CNC(C)=O)ccc1N.Clc1ncc(Cl)c(-c2cnc3ccccn23)n1>>COc1cc(C(CO)CNC(C)=O)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 -US20130190333A1,1,CC[C@@H](c1cccc(O)c1)[C@@H](C)CN(C)C.COc1ccc2cc([C@H](C)C(=O)O)ccc2c1>>CC[C@@H](c1cccc(OC(=O)[C@@H](C)c2ccc3cc(OC)ccc3c2)c1)[C@@H](C)CN(C)C -US20120289481A1,6,COc1ccc([C@H](CC(=O)OC(C)(C)C)n2ccn(CCCc3ccc4c(n3)NCCC4)c2=O)cn1>>COc1ccc([C@H](CC(=O)O)n2ccn(CCCc3ccc4c(n3)NCCC4)c2=O)cn1 -US06951879B2,1,CNC.CS(=O)(=O)OCCCC#Cc1ccc2c(-c3ccc(Br)cc3)nsc2c1>>CN(C)CCCC#Cc1ccc2c(-c3ccc(Br)cc3)nsc2c1 -US06335459B1,7,CC(C)(C)OC(=O)C=Cc1cccc(Br)c1>>CC(C)(C)OC(=O)CCc1cccc(Br)c1 -US03989501,1,COC(=N)N.COC(=O)Cl>>COC(=O)N=C(N)OC -US06313299B1,1,CON=C1CNCC12CN(C(=O)OC(C)(C)C)C2.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>CON=C1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC12CN(C(=O)OC(C)(C)C)C2 -US07173025B1,2,COC(=O)c1ccc(S(=O)(=O)c2ccc3cc(Br)ccc3c2)cc1C(=O)O.c1cc(N2CCNCC2)ccn1>>COC(=O)c1ccc(S(=O)(=O)c2ccc3cc(Br)ccc3c2)cc1C(=O)N1CCN(c2ccncc2)CC1 -US20110236690A1,7,O=Cc1scc2c1OCCO2>>OCc1scc2c1OCCO2 -US20090143364A1,2,CCOc1cc(C(C)(C)C#N)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.CN(CCC#N)C(=O)CN1CCNCC1>>CCOc1cc(C(C)(C)C#N)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N(C)CCC#N)CC1 -US04841039,9,CCc1cn([C@H]2C[C@H](I)[C@@H](CO)O2)c(=O)[nH]c1=O>>CCc1cn([C@H]2CC[C@@H](CO)O2)c(=O)[nH]c1=O -US08349836B2,1,O=c1[nH]nc(Cl)c2cc(Br)ccc12.c1cnc(N2CCNCC2)cn1>>O=c1[nH]nc(Cl)c2cc(N3CCN(c4cnccn4)CC3)ccc12 -US09066948B2,7,CC(C)(C)OC(=O)N1CCN(c2cc(=O)n3nc(-c4cccc([N+](=O)[O-])c4)sc3n2)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(=O)n3nc(-c4cccc(N)c4)sc3n2)CC1 -US20120316161A1,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.CCCC(C(=O)OCC)c1c(C)nc2ccnn2c1Cl>>CCCC(C(=O)OCC)c1c(C)nc2ccnn2c1N1CC[C@@H](NC(=O)OC(C)(C)C)C1 -US08148383B2,1,CC(C)(C)[Si](C)(C)OC1CCC(=O)CC1.Nc1cnnn1Cc1ccccc1>>CC(C)(C)[Si](C)(C)OC1CCC(Nc2cnnn2Cc2ccccc2)CC1 -US20050143381A1,1,BrCc1ccc(-c2ccno2)cc1.O=c1[nH]nc2c(-c3ccncc3)c(-c3ccc(F)cc3)cnn12>>O=c1n(Cc2ccc(-c3ccno3)cc2)nc2c(-c3ccncc3)c(-c3ccc(F)cc3)cnn12 -US07132436B2,2,Nc1nc(-c2ccc(Oc3ccc(Cl)cc3)cc2Cl)cs1.O=S(=O)(Cl)c1cc(F)c(Br)cc1F>>O=S(=O)(Nc1nc(-c2ccc(Oc3ccc(Cl)cc3)cc2Cl)cs1)c1cc(F)c(Br)cc1F -US05935974,1,CCOC(=O)C1CCNCC1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)C1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1 -US06693114B2,2,COc1nc2c(cc1I)c(=O)c(C(=O)O)cn2C.NCc1ccc(Cl)cc1>>COc1nc2c(cc1I)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C -US20150099737A1,1,CN(C)C(=O)c1cc2cnc(Cl)nc2n1C1CCCCCC1.Nc1ccc(N2C(=O)CN3CCC2CC3)cn1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(N4C(=O)CN5CCC4CC5)cn3)nc2n1C1CCCCCC1 -US20030138663A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=[N+]([O-])c1ccccc1I>>O=[N+]([O-])c1ccccc1-c1ccccn1 -US05367113,2,CC(=O)OC(C)=O.N#CCCCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCNOCc1ccccc1>>CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCC#N)OCc1ccccc1)OCc1ccccc1)OCc1ccccc1 -US20040198702A1,2,CC(=O)Cl.OCCCC(F)=C(F)F>>CC(=O)OCCCC(F)=C(F)F -US20050143421A1,3,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=O)CC3)c(F)c2)C(=O)O1.Nc1cccc([N+](=O)[O-])c1.[C-]#N>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(C#N)(Nc4cccc([N+](=O)[O-])c4)CC3)c(F)c2)C(=O)O1 -US20110294850A1,2,O=C=NCc1ccco1.Oc1ccc2c(c1)CCN2Cc1ccccc1>>O=C(NCc1ccco1)Oc1ccc2c(c1)CCN2Cc1ccccc1 -US20150164904A1,2,CCN(CC)CCN(C)Cc1ccc(C(=O)O)cc1.Nc1ccc(N2CCCCC2)cc1C(=O)Nc1ccn(-c2cccc(C(F)(F)F)c2)n1>>CCN(CC)CCN(C)Cc1ccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2ccn(-c3cccc(C(F)(F)F)c3)n2)cc1 -US20120230951A1,2,COC(=O)N[C@H](C(=O)N1CC2(C[C@H]1C(=O)O)OCCO2)C(C)C.NCC(=O)c1ccc(Br)cc1>>COC(=O)N[C@H](C(=O)N1CC2(C[C@H]1C(=O)NCC(=O)c1ccc(Br)cc1)OCCO2)C(C)C -US20110237784A1,1,BrCc1ccccc1.Cc1cc(O)ccc1C(=O)O>>Cc1cc(O)ccc1C(=O)OCc1ccccc1 -US04303655,7,CCOC(=O)C(=O)c1csc(NS(C)(=O)=O)n1>>CCOC(=O)C(O)c1csc(NS(C)(=O)=O)n1 -US04189485,1,CNC.Clc1cccc(Cl)c1Cn1cnc2c(Cl)ncnc21>>CN(C)c1ncnc2c1ncn2Cc1c(Cl)cccc1Cl -US20090042929A1,4,C#CCSc1cc(Cl)ccc1Cl.[N-]=[N+]=NC12CC3CC(CC(C3)C1)C2>>Clc1ccc(Cl)c(SCc2cn(C34CC5CC(CC(C5)C3)C4)nn2)c1 -US20130196971A1,3,CC1(C)OB(c2ccc3cccnc3c2)OC1(C)C.O=C(C1CC1)N1CC(Cn2cnnc2-c2ccc(Br)cc2F)C1>>O=C(C1CC1)N1CC(Cn2cnnc2-c2ccc(-c3ccc4cccnc4c3)cc2F)C1 -US20110092553A1,1,COC(=O)C(C)Br.Nc1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(Br)cc2)cc1>>COC(=O)C(C)Nc1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2C=Cc2ccc(Br)cc2)cc1 -US04647569,7,O=[N+]([O-])c1ccc(NC=C(S(=O)(=O)c2ccccc2)S(=O)(=O)c2ccccc2)nc1>>Nc1ccc(NC=C(S(=O)(=O)c2ccccc2)S(=O)(=O)c2ccccc2)nc1 -US20100035918A1,1,Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)[nH]c2=O)c1.Fc1cccc(CBr)c1>>Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)n(Cc3cccc(F)c3)c2=O)c1 -US20090227628A1,1,CN1CCC(N)CC1.Cc1ccc(CNc2ccc3c(Br)cccc3n2)o1>>Cc1ccc(CNc2ccc3c(NC4CCN(C)CC4)cccc3n2)o1 -US05998433,3,C=O.CNC.O=C(CCCCSc1ccccc1)N1CCc2occc2C1>>CN(C)Cc1cc2c(o1)CCN(C(=O)CCCCSc1ccccc1)C2 -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)O)CC1.Cc1cccc(CCN)c1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)NCCc2cccc(C)c2)CC1 -US06515011B2,2,O=C(O)C1(O)c2ccccc2-c2ccccc21.O=C(OCc1ccccc1)[C@@H]1CCCN1>>O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)C1(O)c2ccccc2-c2ccccc21 -US06727264B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.C[C@H](CCl)COc1cccc(F)c1>>CC(C)C(=O)Nc1cccc(C2CCN(C[C@@H](C)COc3cccc(F)c3)CC2)c1 -US20130109652A1,3,Brc1cncc2ccccc12.C#Cc1ccc(OC)cc1>>COc1ccc(C#Cc2cncc3ccccc23)cc1 -US20150166480A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1 -US20120121540A1,2,NCCN1CCOCC1.O=C(O)C1C(c2ccccc2)CCN1C(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl>>O=C(NCCN1CCOCC1)C1C(c2ccccc2)CCN1C(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl -US08067362B2,2,CC(C)(C)OC(=O)CCCCCCCCCCCCCCC(=O)O.CC(C)(C)OC(=O)c1cc(N)cc(C(=O)O)c1>>CC(C)(C)OC(=O)CCCCCCCCCCCCCCC(=O)Nc1cc(C(=O)O)cc(C(=O)OC(C)(C)C)c1 -US05158599,2,Cc1cc(C)nc(OC(C)C(=O)O)n1.NS(=O)(=O)c1ccccc1>>Cc1cc(C)nc(OC(C)C(=O)NS(=O)(=O)c2ccccc2)n1 -US20100041892A1,1,CCCCOc1cc(C(=O)OC)[nH]n1.FC(F)(F)c1ccc(CCl)c(Cl)c1>>CCCCOc1cc(C(=O)OC)n(Cc2ccc(C(F)(F)F)cc2Cl)n1 -US20100125082A1,3,COc1cc(C2(c3cccc(Br)c3)N=C(N)c3c(F)cccc32)ccn1.C[Sn](C)(C)c1cc(C#N)ccn1>>COc1cc(C2(c3cccc(-c4cc(C#N)ccn4)c3)N=C(N)c3c(F)cccc32)ccn1 -US20020137939A1,9,COC1CCCCC1=O.NO>>COC1CCCCC1=NO -US20130109682A1,6,CC(C)(C)[Si](C)(C)OC[C@@H]1CO[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)OC1>>O=C(Nc1cnccc1[C@@H]1OC[C@@H](CO)CO1)c1ccc(F)c(-c2c(F)cccc2F)n1 -US04888428,4,CCOC(=O)Cn1c(=O)sc2cc(F)c(N)cc21.O=C1OC(=O)C2=C1CCCC2>>CCOC(=O)Cn1c(=O)sc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21 -US20060148858A1,7,CCOC(=O)CCc1cn(-c2ccc(Cl)cn2)nc1C(C)C>>CC(C)c1nn(-c2ccc(Cl)cn2)cc1CCCO -US20130345215A1,7,Cn1ncc2c(=O)[nH]c(N3CCN(c4c(F)cc([N+](=O)[O-])cc4F)CC3)nc21>>Cn1ncc2c(=O)[nH]c(N3CCN(c4c(F)cc(N)cc4F)CC3)nc21 -US08816090B2,1,COC(=O)C1(C=O)CCOCC1.OCC1(COc2cccc3onc(OCC4CCNCC4)c23)CCCC1>>COC(=O)C1(CN2CCC(COc3noc4cccc(OCC5(CO)CCCC5)c34)CC2)CCOCC1 -US05594135,6,COc1cc(O[Si](C)(C)C(C)(C)C(C)C)c2c(c1C)C(=O)OC[C@H](COC(=O)c1ccc(CN)cc1)CCC(=S)N[C@H](c1nc(C)no1)CSC2>>COc1cc(O)c2c(c1C)C(=O)OC[C@H](COC(=O)c1ccc(CN)cc1)CCC(=S)N[C@H](c1nc(C)no1)CSC2 -US07569582B2,6,CCN(CC)C(=O)N(C1CCCCC1)C1CC2CCC(C1)N2C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)OC(C)(C)C>>CCN(CC)C(=O)N(C1CCCCC1)C1CC2CCC(C1)N2C(=O)[C@H](N)Cc1ccc(Cl)cc1 -US07807674B2,1,CC(C)c1cc(Cl)nnc1Cl.OCCc1cc(Br)c(O)c(Br)c1>>CC(C)c1cc(Oc2c(Br)cc(CCO)cc2Br)nnc1Cl -US07326791B2,2,CC[C@H](N)c1nc2cc(Cl)ccc2[nH]1.Cc1cc(C(=O)O)ccc1C(=O)N1CCCC1>>CC[C@H](NC(=O)c1ccc(C(=O)N2CCCC2)c(C)c1)c1nc2cc(Cl)ccc2[nH]1 -US06008185,7,O=C1CCCCCCCCCCC(=O)OCCC1>>O=C1CCCCCCCCCCC(O)CCCO1 -US20080280906A1,2,CCNc1cnoc1C.O=C(Cl)C(F)F>>CCN(C(=O)C(F)F)c1cnoc1C -US20020086858A1,3,C=Cc1ccccn1.Cc1cc(N2CCCC2)nc(Cl)n1>>Cc1cc(N2CCCC2)nc(/C=C/c2ccccn2)n1 -US20120258991A1,1,CC(C)(C)[Si](C)(C)Oc1ccc(Br)cc1.CNCC(C)C>>CC(C)CN(C)c1ccc(O[Si](C)(C)C(C)(C)C)cc1 -US06340679B1,2,CC(C)(C)OC(=O)[C@H](Cc1ccc(OCCCC(=O)O)cc1)NS(=O)(=O)c1cccc2ccccc12.NC1=NCCCN1>>CC(C)(C)OC(=O)[C@H](Cc1ccc(OCCCC(=O)NC2=NCCCN2)cc1)NS(=O)(=O)c1cccc2ccccc12 -US20120101100A1,6,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cc(-c3n[nH]c(=O)o3)cnc2OC2CCN(C(=O)OC(C)(C)C)CC2)cn1>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cc(-c3n[nH]c(=O)o3)cnc2OC2CCNCC2)cn1 -US20050148623A1,8,CCOC(=O)C1=NOC(CC(O)C(C)(C)C)C1>>CCOC(=O)C1=NOC(CC(=O)C(C)(C)C)C1 -US20080058384A1,2,CC1=C(C(=O)O)C(c2ccc(C(F)(F)F)cc2F)CC(=O)N1.Nc1cc2c(Cl)n[nH]c2cc1F>>CC1=C(C(=O)Nc2cc3c(Cl)n[nH]c3cc2F)C(c2ccc(C(F)(F)F)cc2F)CC(=O)N1 -US20080194630A1,2,CC(=O)OC(C)=O.NCCCN(CCc1ccc(Oc2nc3ccccc3s2)cc1)CC1CC1>>CC(=O)NCCCN(CCc1ccc(Oc2nc3ccccc3s2)cc1)CC1CC1 -US20120157436A1,2,O=C(Cl)c1cccc(Cl)c1Cl.c1nsc(-c2nnc3n2CCNC3)n1>>O=C(c1cccc(Cl)c1Cl)N1CCn2c(nnc2-c2ncns2)C1 -US20100240656A1,1,CCCCn1c(Br)nc(C(N)=O)c1N.Sc1nc(-c2ccccc2)cs1>>CCCCn1c(Sc2nc(-c3ccccc3)cs2)nc(C(N)=O)c1N -US20100056524A1,1,CN1CCN(CCO)CC1.O=[N+]([O-])c1ccc(Cl)nc1>>CN1CCN(CCOc2ccc([N+](=O)[O-])cn2)CC1 -US20110257151A1,9,COC(=O)c1c(Cl)ccc2c1C(O)C(C)(C)C(c1cccc(Br)c1)N2>>COC(=O)c1c(Cl)ccc2c1CC(C)(C)C(c1cccc(Br)c1)N2 -US20150141437A1,2,CN(CC(O)COc1ccccc1C(=O)O)C1C2CC3CC(C2)CC1C3.NCc1ccc(C2(C(F)(F)F)N=N2)cc1>>CN(CC(O)COc1ccccc1C(=O)NCc1ccc(C2(C(F)(F)F)N=N2)cc1)C1C2CC3CC(C2)CC1C3 -US20140200207A1,1,C[Si](C)(C)CCOCn1cc(I)c2c(Cl)nc(Cl)nc21.OC1CCC1>>C[Si](C)(C)CCOCn1cc(I)c2c(OC3CCC3)nc(Cl)nc21 -US20140051702A1,1,CN1CCCC1CCCl.c1ccc(NC2Cc3ccccc3C2)cc1>>CN1CCCC1CCN(c1ccccc1)C1Cc2ccccc2C1 -US20130225584A1,2,Nc1cccc(F)c1.O=C(O)c1cc(C(F)(F)F)c(CN2CCOCC2)cc1OCc1ccccc1>>O=C(Nc1cccc(F)c1)c1cc(C(F)(F)F)c(CN2CCOCC2)cc1OCc1ccccc1 -US07332497B2,1,COc1cc(-c2nn(CCOS(C)(=O)=O)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C.NCCO>>COc1cc(-c2nn(CCNCCO)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C -US20080119491A1,2,Nc1ccc(F)c(Cl)c1.O=C(O)c1ccc(-c2ccccc2)cc1>>O=C(Nc1ccc(F)c(Cl)c1)c1ccc(-c2ccccc2)cc1 -US07348324B2,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Oc1ccncc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccncc2)CC1 -US05849764,7,COc1ccc(-c2[nH]c3ccccc3c2CCNC(=O)CCc2ccc3[nH]ccc3c2)cc1OC>>COc1ccc(-c2[nH]c3ccccc3c2CCNCCCc2ccc3[nH]ccc3c2)cc1OC -US07915411B2,1,Cc1cccc(CBr)c1.O=[N+]([O-])c1cc(O)ccc1Cl>>Cc1cccc(COc2ccc(Cl)c([N+](=O)[O-])c2)c1 -US08906944B2,6,COC(=O)C1CCCN1CCCNC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)ccn2)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCCN5CCCC5C(=O)O)c[nH]4)c3)cc2F)c1 -US20060122185A1,2,COc1cccc(CC(=O)O)c1.Nc1nnc(-c2c[nH]c3ncncc23)s1>>COc1cccc(CC(=O)Nc2nnc(-c3c[nH]c4ncncc34)s2)c1 -US05798316,1,COC(=O)C(C)Br.O=Cc1ccc(O)cc1>>COC(=O)C(C)Oc1ccc(C=O)cc1 -US20110244481A1,3,CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(Br)n2)cc1.OB(O)/C=C/c1ccccc1>>CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(/C=C/c3ccccc3)n2)cc1 -US20050131014A1,2,Cc1ccc(N)cc1.O=C(O)c1cnc2c(C(F)(F)F)cccc2c1-c1ccccc1>>Cc1ccc(NC(=O)c2cnc3c(C(F)(F)F)cccc3c2-c2ccccc2)cc1 -US06703425B2,6,CC(CNS(=O)(=O)C(C)C)c1cccc(CCNC(=O)OCc2ccccc2)c1>>CC(CNS(=O)(=O)C(C)C)c1cccc(CCN)c1 -US20050107449A1,6,CCOC(=O)COc1ccc(SC(C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2CCc2c(F)cccc2Cl)cc1C>>Cc1cc(SC(C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2CCc2c(F)cccc2Cl)ccc1OCC(=O)O -US04167638,7,COc1cc([N+](=O)[O-])c2nc(OCc3ccc(Cl)cc3)ccc2c1>>COc1cc(N)c2nc(OCc3ccc(Cl)cc3)ccc2c1 -US08815901B2,2,CN1CCN(Cc2ccc(N)nc2)CC1.COc1cc(OC)c(Cl)c(-c2ccc(C(=O)O)c3nc(C)c(C)nc23)c1Cl>>COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3nc(C)c(C)nc23)c1Cl -US20070093521A1,1,CCOc1cc(C=O)cc(OCC)c1F.O=C(Nc1cccnc1)c1cccc2oc(NC3CCNCC3)nc12>>CCOc1cc(CN2CCC(Nc3nc4c(C(=O)Nc5cccnc5)cccc4o3)CC2)cc(OCC)c1F -US06617329B2,1,CS(=O)(=O)OC[C@H]1CCC(=O)O1.Fc1ccc(Nc2ncnc3cc(OCCN4CCNCC4)c(OC4CCCC4)cc23)cc1Cl>>O=C1CC[C@H](CN2CCN(CCOc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3OC3CCCC3)CC2)O1 -US20150246912A1,6,CC(C)(CO[Si](C)(C)C(C)(C)C)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)c2cncc(F)c21>>CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)c2cncc(F)c21 -US07507841B2,7,COc1cc(C(C)C)ccc1-c1coc2c(C)c(C)cc(C)c12>>COc1cc(C(C)C)ccc1C1COc2c(C)c(C)cc(C)c21 -US05594135,2,C=CCOC(=O)c1c(C)c(OC)cc(O[Si](C)(C)C(C)(C)C(C)C)c1CSC[C@H](N)c1nc(C)no1.O=C(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1>>C=CCOC(=O)c1c(C)c(OC)cc(O[Si](C)(C)C(C)(C)C(C)C)c1CSC[C@H](NC(=O)COC(c1ccccc1)(c1ccccc1)c1ccccc1)c1nc(C)no1 -US05196425,1,CC(=O)N1CCC(c2[nH]nc3cc(F)ccc23)CC1.ClCc1ccccc1>>CC(=O)N1CCC(c2c3ccc(F)cc3nn2Cc2ccccc2)CC1 -US04590195,2,CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl.CN1CCN(S(=O)(=O)Cl)CC1>>CCOC(=O)C1=C(COCCNS(=O)(=O)N2CCN(C)CC2)NC(C)=C(C(=O)OC)C1c1ccccc1Cl -US06831174B2,7,CCOC(=O)[C@@H]1O[C@@H](OC(C)=O)CS1>>CC(=O)O[C@H]1CS[C@H](CO)O1 -US20080194617A1,3,C[S+](C)(C)=O.Cc1nn(C)c(-n2ccc3cc(Cl)ccc32)c1/C=C/C(=O)OC(C)(C)C>>Cc1nn(C)c(-n2ccc3cc(Cl)ccc32)c1[C@@H]1C[C@H]1C(=O)OC(C)(C)C -US04404138,1,COc1ccc2c3c(c(=O)oc2c1)CNCC3.ClCCN1CC2CCCC(C2)C1>>COc1ccc2c3c(c(=O)oc2c1)CN(CCN1CC2CCCC(C2)C1)CC3 -US07683064B2,1,CC(=O)OCc1c(Br)cccc1Br.CN(C)c1ccc2c(=O)[nH]ccc2c1>>CC(=O)OCc1c(Br)cccc1-n1ccc2cc(N(C)C)ccc2c1=O -US06147097,1,CI.Cc1nc(C(C)C)c(Sc2cc(Cl)cc(Cl)c2)[nH]1>>Cc1nc(C(C)C)c(Sc2cc(Cl)cc(Cl)c2)n1C -US04185992,3,C[Mg+].O=Cc1ccc(OC(F)(F)F)cc1>>CC(O)c1ccc(OC(F)(F)F)cc1 -US08344135B2,2,CC(C)(C#N)c1cccc(C(=O)Nc2cc(Oc3ccc4nc(N)sc4n3)c(Cl)cc2F)c1.COCC(=O)Cl>>COCC(=O)Nc1nc2ccc(Oc3cc(NC(=O)c4cccc(C(C)(C)C#N)c4)c(F)cc3Cl)nc2s1 -US20040229874A1,1,CN1CCNCC1.Cc1ccc2c(ccn2Cc2ccc(-c3ccccc3Br)cc2)c1>>Cc1ccc2c(ccn2Cc2ccc(-c3ccccc3N3CCN(C)CC3)cc2)c1 -US20110294801A1,2,CN1CCN(c2ccc([N+](=O)[O-])cc2CC(=O)O)CC1.NC(=O)[C@H]1[C@H]2C[C@H]([C@H]([NH3+])C2)[C@H]1Nc1nc(Cl)ncc1F>>CN1CCN(c2ccc([N+](=O)[O-])cc2CC(=O)N[C@@H]2C[C@@H]3C[C@H]2[C@@H](Nc2nc(Cl)ncc2F)[C@H]3C(N)=O)CC1 -US20120309739A1,6,COc1nc(N)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c12>>COc1nc(N)nc2oc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)c12 -US07842685B2,9,Nc1ccc(Cl)nc1Cl.S=C(Cl)Cl>>S=C=Nc1ccc(Cl)nc1Cl -US20030162799A1,1,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C.Clc1ncccn1>>COC(=O)[C@H](Cc1ccc(Oc2ncccn2)cc1)NC(=O)OC(C)(C)C -US06716856B1,4,CC(=O)C1C(=O)CC(C)(C)CC1=O.NNc1ccccn1>>Cc1nn(-c2ccccn2)c2c1C(=O)CC(C)(C)C2 -US05036086,2,COCC(=O)Cl.Cc1ccc2nc(N)sc2c1>>COCC(=O)Nc1nc2ccc(C)cc2s1 -US05998433,2,O=C(O)c1ccc(C(=O)c2cccc(Cl)c2)cc1.c1cc2c(o1)CNCC2>>O=C(c1ccc(C(=O)N2CCc3ccoc3C2)cc1)c1cccc(Cl)c1 -US04922021,2,CC(O)CNc1c(Cl)cccc1Cl.CS(=O)(=O)Cl>>CC(CNc1c(Cl)cccc1Cl)OS(C)(=O)=O -US20060009511A9,7,O=[N+]([O-])c1ccc2[nH]cc(CCNCc3cccc(Oc4ccccc4)c3)c2c1>>Nc1ccc2[nH]cc(CCNCc3cccc(Oc4ccccc4)c3)c2c1 -US07893099B2,7,CCOC(=O)[C@@H]1CC(=O)C[C@H]1C(=O)NCC#N>>CCOC(=O)[C@@H]1C[C@H](O)C[C@H]1C(=O)NCC#N -US05665718,9,NC(=O)c1ncn2c1[C@@H]1CCN1C(=O)c1cc(F)ccc1-2>>N#Cc1ncn2c1[C@@H]1CCN1C(=O)c1cc(F)ccc1-2 -US06191124B1,7,CCOC(=O)c1cnc2sc3cc(OC)ccc3n12>>COc1ccc2c(c1)sc1ncc(CO)n12 -US07947676B2,1,Cc1ccc(Oc2ccc(Nc3ncnc4[nH]nc(OCCCl)c34)cc2C)cn1.O[C@@H]1CCNC1>>Cc1ccc(Oc2ccc(Nc3ncnc4[nH]nc(OCCN5CC[C@@H](O)C5)c34)cc2C)cn1 -US20090099183A1,1,CCc1ccc(Cl)cc1-c1cc(Cl)nc(N)n1.Nc1ccc(CCO)cc1>>CCc1ccc(Cl)cc1-c1cc(Nc2ccc(CCO)cc2)nc(N)n1 -US05480899,6,COC(=O)c1ccc(OCC2CN(c3ccc([N+](=O)[O-])cc3)C(=O)O2)cc1>>O=C(O)c1ccc(OCC2CN(c3ccc([N+](=O)[O-])cc3)C(=O)O2)cc1 -US05145858,1,CCS.Fc1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1>>CCSc1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1 -US20150057260A1,9,CCOC(=O)c1nc(-c2cc(C#C[C@]3(O)CCN(C)C3=O)ccc2F)ncc1NCCOC.N>>COCCNc1cnc(-c2cc(C#C[C@]3(O)CCN(C)C3=O)ccc2F)nc1C(N)=O -US20080056991A1,1,C1CCNCC1.CC(C)N1CCN(C(=O)c2cccc(C=O)c2)CC1>>CC(C)N1CCN(C(=O)c2cccc(CN3CCCCC3)c2)CC1 -US07820704B2,6,CC(C)c1ccc(-c2csc(N(Cc3cccs3)S(=O)(=O)CC(=O)OC(C)(C)C)n2)cc1>>CC(C)c1ccc(-c2csc(N(Cc3cccs3)S(=O)(=O)CC(=O)O)n2)cc1 -US04268510,2,CCCCO.O=C(Cl)c1ccc2c(c1)C(=O)NC(C(Cl)(Cl)Cl)O2>>CCCCOC(=O)c1ccc2c(c1)C(=O)NC(C(Cl)(Cl)Cl)O2 -US08084621B2,2,Cc1[nH]c2c(c1C(=O)O)CCCC2=O.NCC(O)CN1CCCC1>>Cc1[nH]c2c(c1C(=O)NCC(O)CN1CCCC1)CCCC2=O -US20050154062A1,2,Cc1cc(C)cc(N)c1.O=C(O)Cc1ccc(O)cc1>>Cc1cc(C)cc(NC(=O)Cc2ccc(O)cc2)c1 -US07435744B2,7,O=C(Nc1cccc([N+](=O)[O-])c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>Nc1cccc(NC(=O)C(=O)N2CCC(Cc3ccc(F)cc3)CC2)c1 -US05321025,1,CI.COC1(c2cc(F)cc(Sc3ccc4c(c3)O[C@H](C)C(=O)N4)c2)CCOCC1>>COC1(c2cc(F)cc(Sc3ccc4c(c3)O[C@H](C)C(=O)N4C)c2)CCOCC1 -US08513184B2,2,C=CCC[C@@H](OC)[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1cccc(O[Si](C)(C)C(C)(C)C)c1)C(=O)N1CCC[C@@H](C(=O)O)N1)C(C)C.C=Cc1cccc([C@@H](C)N)c1>>C=CCC[C@@H](OC)[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1cccc(O[Si](C)(C)C(C)(C)C)c1)C(=O)N1CCC[C@@H](C(=O)N[C@H](C)c2cccc(C=C)c2)N1)C(C)C -US20080311113A1,1,CC1(C)OB(c2ccc(CBr)cc2)OC1(C)C.Oc1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12>>CC1(C)OB(c2ccc(COc3cc(C(F)(F)F)nc4c(C(F)(F)F)cccc34)cc2)OC1(C)C -US08785436B2,1,CC(C)(C)[S@@](N)=O.O=C(c1cc(Br)ccc1F)C(F)F>>CC(C)(C)[S@](=O)/N=C(\c1cc(Br)ccc1F)C(F)F -US20090275567A1,1,BrCCc1ccccc1.Cc1ncc(-c2ccnc(NC3CCNCC3)n2)n1C(C)C>>Cc1ncc(-c2ccnc(NC3CCN(CCc4ccccc4)CC3)n2)n1C(C)C -US07446222B2,2,CCO.O=C(O)c1cc(Cl)ccc1Br>>CCOC(=O)c1cc(Cl)ccc1Br -US06967197B2,5,CC(C)(C)OC(=O)C[C@]1(c2ccc(Br)s2)CCNCCS1(=O)=O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)C[C@]1(c2ccc(Br)s2)CCN(C(=O)OC(C)(C)C)CCS1(=O)=O -US06465507B2,3,COc1ccc2c(c1)CC(=O)N2.O=Cc1[nH]cc2c1CCOC2=O>>COc1ccc2c(c1)C(=Cc1[nH]cc3c1CCOC3=O)C(=O)N2 -US08680108B2,1,CC(=O)NC1CCNCC1.CC(=O)c1cc(Cl)c2cccnc2c1OS(=O)(=O)C(F)(F)F>>CC(=O)NC1CCN(c2c(C(C)=O)cc(Cl)c3cccnc23)CC1 -US04041064,10,CCCCCC(=O)CP(=O)(OC)OC.O=C1CCC(=O)N1Br>>CCCCCC(=O)C(Br)P(=O)(OC)OC -US20060004029A1,1,C1CNC1.CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)N4CCC(=O)CC4)c3)ccc21>>CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)N4CCC(N5CCC5)CC4)c3)ccc21 -US20140235855A1,1,C=CCO.COc1ccc2nccc(Br)c2c1>>C=CCOc1ccnc2ccc(OC)cc12 -US20110245310A1,7,CC(C)c1nc2c(n1Cc1ccc(Cl)c(Cl)c1)C(=O)CCC2>>CC(C)c1nc2c(n1Cc1ccc(Cl)c(Cl)c1)C(O)CCC2 -US20100009959A1,6,C#CCn1c(-c2ccc(OC)cc2CO[Si](C(C)C)(C(C)C)C(C)C)c(C2CCCCC2)c2ccc(C(=O)OC)cc21>>C#CCn1c(-c2ccc(OC)cc2CO)c(C2CCCCC2)c2ccc(C(=O)OC)cc21 -US20150259350A1,1,CN1CCNCC1.Cn1cc(-c2cnc3nnn(C[C@@H]4CN(c5ncc(-c6ccc(C=O)c(F)c6)cn5)CCO4)c3n2)cn1>>CN1CCN(Cc2ccc(-c3cnc(N4CCO[C@H](Cn5nnc6ncc(-c7cnn(C)c7)nc65)C4)nc3)cc2F)CC1 -US05556867,1,CC(C)(C)c1ccc(O)cc1.COC(CBr)OC>>COC(COc1ccc(C(C)(C)C)cc1)OC -US20140018335A1,1,COc1ccc2[nH]c(-c3ccccc3)cc2c1.N#Cc1cccc(CCl)n1>>COc1ccc2c(c1)cc(-c1ccccc1)n2Cc1cccc(C#N)n1 -US20100004222A1,2,CC(C)(C)C(=O)OCc1nc2cc(N)cnc2s1.Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)O>>Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)Nc1cnc2sc(COC(=O)C(C)(C)C)nc2c1 -US06806273B1,1,Clc1nc(SCc2ccccc2)nc2nc(Br)sc12.NCCOc1ccccc1>>Clc1nc(SCc2ccccc2)nc2nc(NCCOc3ccccc3)sc12 -US20090227799A1,1,C=O.O=C(NCc1ccc(NCc2ccccc2)cc1)c1ccc2ncccc2c1>>CN(Cc1ccccc1)c1ccc(CNC(=O)c2ccc3ncccc3c2)cc1 -US20040006067A1,6,CC(C)(C)OC(=O)N1CC(C(=O)N[C@H](Cc2ccc(Cl)cc2)C(=O)N2CCC(c3ccccc3NS(C)(=O)=O)CC2)C1>>CS(=O)(=O)Nc1ccccc1C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)C2CNC2)CC1 -US20050176775A1,1,COC(=O)c1cccc(-n2c(C)cc(O)cc2=O)c1C.Fc1ccc(CBr)c(F)c1>>COC(=O)c1cccc(-n2c(C)cc(OCc3ccc(F)cc3F)cc2=O)c1C -US07348339B2,3,Nc1nonc1-c1nc2cncc(Br)c2n1-c1ccccc1.OB(O)c1cccs1>>Nc1nonc1-c1nc2cncc(-c3cccs3)c2n1-c1ccccc1 -US05888941,4,COC(=O)C(Cl)C(C)=O.N#Cc1ccc(C(N)=S)cc1>>COC(=O)c1sc(-c2ccc(C#N)cc2)nc1C -US06518257B1,3,Brc1ccc(Br)cc1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc(Br)cc2)cc1 -US08044069B2,2,CC(C)(C)OC(=O)N1CCC(Nc2ccc(C(F)(F)F)cc2)CC1.O=C(Br)CBr>>CC(C)(C)OC(=O)N1CCC(N(C(=O)CBr)c2ccc(C(F)(F)F)cc2)CC1 -US07709471B2,1,COC(=O)c1ccc(N)c(O)c1.COCCBr>>COCCOc1cc(C(=O)OC)ccc1N -US20090306041A1,1,Brc1cccc(Br)c1.CN(C)c1ccc2c(=O)[nH]ccc2c1>>CN(C)c1ccc2c(=O)n(-c3cccc(Br)c3)ccc2c1 -US20090004185A1,1,NC1CCC1.O=C(Nc1ccc(CNc2nc(Cl)nc3ccc(C(F)(F)F)cc23)cc1)C1CCN(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc(CNc2nc(NC3CCC3)nc3ccc(C(F)(F)F)cc23)cc1)C1CCN(Cc2ccc(F)cc2)CC1 -US05736548,1,ClCCN1CCCC1.O=Cc1cccc(O)c1>>O=Cc1cccc(OCCN2CCCC2)c1 -US07094801B2,2,CC(C)(C)[SiH2]OC(C)(C)C(CO)CO[Si](C)(C)C(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)[SiH2]OC(C)(C)C(CO[Si](C)(C)C(C)(C)C)COS(C)(=O)=O -US08404673B2,2,N[C@H]1CCCC[C@H]1N.O=C(O)c1ccc(C(F)(F)F)cc1C1CC1>>N[C@H]1CCCC[C@H]1NC(=O)c1ccc(C(F)(F)F)cc1C1CC1 -US05807885,7,CN(CCc1ccc([N+](=O)[O-])cc1)C(=O)C(F)(F)F>>CN(CCc1ccc(N)cc1)C(=O)C(F)(F)F -US05602137,1,CCc1cc(Cl)n2nccc2n1.N#Cc1ccccc1-c1ccc(N)cc1>>CCc1cc(Nc2ccc(-c3ccccc3C#N)cc2)n2nccc2n1 -US07846960B2,6,COC(=O)c1cccc(SC(C)(C)c2ccc(OCc3c(C(C)C)cnn3-c3c(Cl)cccc3Cl)cc2C)c1>>Cc1cc(OCc2c(C(C)C)cnn2-c2c(Cl)cccc2Cl)ccc1C(C)(C)Sc1cccc(C(=O)O)c1 -US20130029962A1,7,CC(C)(C)[Si](C)(C)OCCc1ccc([N+](=O)[O-])cn1>>CC(C)(C)[Si](C)(C)OCCc1ccc(N)cn1 -US07687282B2,6,CCCC(=O)Oc1cc2oc(=O)c(C(=O)NCC(=O)OCc3ccccc3)cc2cc1Cl>>CCCC(=O)Oc1cc2oc(=O)c(C(=O)NCC(=O)O)cc2cc1Cl -US06156754,1,CO.C[C@@H]1O[C@H](Oc2ccc([N+](=O)[O-])cc2)[C@@H](O)[C@H](O)[C@@H]1O>>CO[C@@H]1[C@H](O)[C@H](C)O[C@H](Oc2ccc([N+](=O)[O-])cc2)[C@H]1O -US05028606,6,CCOC(=O)c1nc2cc(C(C(C)C)n3ccnc3)ccc2[nH]c1=O>>CC(C)C(c1ccc2[nH]c(=O)c(C(=O)O)nc2c1)n1ccnc1 -US04734407,7,COC(=O)c1ccc2[nH]ccc2c1>>OCc1ccc2[nH]ccc2c1 -US20070054916A1,7,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2nc(C#CCN(C)C)ncc2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2nc(CCCN(C)C)ncc2c1 -US20110124878A1,7,COC(=O)Cn1ncc2cc(Oc3ccc(F)cc3CNC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)ccc21>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)ccc2Oc2ccc3c(cnn3CCO)c2)cc1 -US04052509,1,CCc1ccc(=O)[nH]c1.Ic1ccccc1>>CCc1ccc(=O)n(-c2ccccc2)c1 -US08501732B2,2,COC(=O)c1c(CN)c(=O)c2ccc(Cl)cc2n1-c1ccccc1.O=C(Cl)N1CCOCC1>>COC(=O)c1c(CNC(=O)N2CCOCC2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 -US06011174,1,COc1cc(C=O)ccc1O.Ic1ccccc1>>COc1cc(C=O)ccc1Oc1ccccc1 -US20130040930A1,1,CC1CCC(=O)N1.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Cl)cc2N2CCN(C)C2=O)CC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3C(=O)CCC3C)cc2N2CCN(C)C2=O)CC1 -US07935699B2,2,CC(C)(C)[Si](C)(C)OCCn1ccc(N)n1.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)O)cc1C#N>>CC(C)(C)[Si](C)(C)OCCn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(C#N)c2)n1 -US06410566B1,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)Nc1cc(F)c(F)cc1C(=O)NCC(=O)NCC1CCN(Cc2ccc(O)c(N)c2)CC1>>CC(=O)Nc1cc(CN2CCC(CNC(=O)CNC(=O)c3cc(F)c(F)cc3NC(=O)OC(C)(C)C)CC2)ccc1O -US05162322,1,CN1CC(CCCCCl)OC1=O.c1ccc(N2CCNCC2)cc1>>CN1CC(CCCCN2CCN(c3ccccc3)CC2)OC1=O -US05310743,6,O=C(c1ccccc1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1>>O=C(c1ccccc1)N1CC[C@H](NCc2ccnc3ccccc23)C[C@H]1Cc1ccccc1 -US20130123277A1,1,BrC=C(c1ccccc1)c1ccccc1.CN1CCc2c([nH]c3ccc(Cl)cc23)C1>>CN1CCc2c(n(C=C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)C1 -US20150266857A1,6,COCCS(=O)(=O)NCc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1>>O=S(=O)(CCO)NCc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1 -US06380218B1,7,O=C(NCc1ccccc1Cl)c1cccnc1Oc1cccc([N+](=O)[O-])c1>>Nc1cccc(Oc2ncccc2C(=O)NCc2ccccc2Cl)c1 -US20120264735A1,7,Cn1cc(-n2ccc(=O)c(C(=O)c3ccc4ncccc4c3)n2)cn1>>Cn1cc(-n2ccc(=O)c(C(O)c3ccc4ncccc4c3)n2)cn1 -US20030114432A1,7,CCOC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CN(C(C)=O)c1ccc([N+](=O)[O-])cc1-2>>CCOC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CN(C(C)=O)c1ccc(N)cc1-2 -US06448243B1,9,COC(=O)C1CN(CCC2(F)C=CC=CC2)CCC1=O>>O=C1CCN(CCC2(F)C=CC=CC2)CC1 -US06982348B2,7,CCOC(=O)C(Cc1ccc(C(F)(F)F)cc1)C(=O)c1ccc(Cl)nc1>>CCOC(=O)C(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(Cl)nc1 -US20130029938A1,1,CC(C)(C)OC(=O)CN.CCCC[C@]1(CC)CS(=O)(=O)c2cc(C=O)c(OC)cc2[C@H](c2ccccc2)N1>>CCCC[C@]1(CC)CS(=O)(=O)c2cc(CNCC(=O)OC(C)(C)C)c(OC)cc2[C@H](c2ccccc2)N1 -US20150037526A1,2,C=CC(=O)Cl.CCCCCCCCCC=CO>>C=CC(=O)OC=CCCCCCCCCC -US06995182B2,1,Cc1ccc(S(=O)(=O)N2[C@@H](CCCCCl)CC[C@H]2c2ccc(F)cc2)cc1.c1c[nH]cn1>>Cc1ccc(S(=O)(=O)N2[C@@H](CCCCn3ccnc3)CC[C@H]2c2ccc(F)cc2)cc1 -US05134154,1,CCOC(=O)C(Br)c1ccccc1.COc1ccccc1O>>CCOC(=O)C(Oc1ccccc1OC)c1ccccc1 -US20150190457A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1CCCCC1O>>CC(C)(C)OC(=O)NCC1CCCCC1O -US20130303515A1,6,CCOC(=O)C1(C)CCN1C(=O)Cc1cc(C)cc(C)c1>>Cc1cc(C)cc(CC(=O)N2CCC2(C)C(=O)O)c1 -US20150239893A1,6,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)Nc1cccc(-c2ncccc2Cl)c1F>>O=C(Nc1cccc(-c2ncccc2Cl)c1F)[C@@H]1C[C@@H](F)CN1 -US07932255B2,2,CC(C)[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N1CCNC[C@H]1C(=O)N[C@@H]1CCCc2ccccc21.CN(C(=O)Cl)c1ccccc1>>CC(C)[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N1CCN(C(=O)N(C)c2ccccc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21 -US20090149524A1,2,Cc1n[nH]c(C)c1CC(=O)O.N[C@H]1CCCc2ccccc21>>Cc1n[nH]c(C)c1CC(=O)NC1CCCc2ccccc21 -US05719145,2,CCCCO.O=C(O)CC1COc2ccc(NC(=O)c3ccc(C=NN4CCOCC4)cc3)cc2C1>>CCCCOC(=O)CC1COc2ccc(NC(=O)c3ccc(C=NN4CCOCC4)cc3)cc2C1 -US08034812B2,2,CCOC(=O)c1cn2nc(I)ccc2n1.CN>>CNC(=O)c1cn2nc(I)ccc2n1 -US20100069367A1,7,CCOC(=O)c1cn(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2Cl)c(-c2ccccc2Cl)n1>>CS(=O)(=O)c1cccc(-c2ccc(-n3cc(CO)nc3-c3ccccc3Cl)c(Cl)c2)c1 -US20060173050A1,2,CC(C)(C)CC(=O)Cl.CCOc1nc(N)cc(N)c1C#N>>CCOc1nc(NC(=O)CC(C)(C)C)cc(N)c1C#N -US04250186,6,COc1cc(N=C2NCCN2)ccc1C>>Cc1ccc(N=C2NCCN2)cc1O -US08586614B2,6,CCOC(=O)CSc1cnc(NC(=O)N(CC2CCCC2)c2cccc(Cl)c2F)s1>>O=C(O)CSc1cnc(NC(=O)N(CC2CCCC2)c2cccc(Cl)c2F)s1 -US08552181B2,1,CC(C)(C)[S@](N)=O.O=CC(F)c1ccccc1>>CC(C)(C)[S@@](=O)/N=C/C(F)c1ccccc1 -US05283248,9,CCOC(=O)Cc1nc2cc(F)c(N3CCN(C(=O)OC(C)(C)C)CC3)cc2n1C1CC1.[NH4+]>>CC(C)(C)OC(=O)N1CCN(c2cc3c(cc2F)nc(CC(N)=O)n3C2CC2)CC1 -US07354942B2,6,CCCN(c1cc(COCC(C)(Cc2ccccc2)NC(=O)OC(C)(C)C)cc(C(=O)O)c1)S(C)(=O)=O>>CCCN(c1cc(COCC(C)(N)Cc2ccccc2)cc(C(=O)O)c1)S(C)(=O)=O -US20040220215A1,1,CCOC(=O)c1sc(Cl)nc1C.Sc1ccccc1>>CCOC(=O)c1sc(Sc2ccccc2)nc1C -US20020087002A1,1,COc1ccc(F)cc1CCl.OCCCCl>>COc1ccc(F)cc1COCCCCl -US07919502B2,2,Clc1ccc(N2CCNCC2)cc1.O=C(O)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1>>O=C(c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1)N1CCN(c2ccc(Cl)cc2)CC1 -US03952031,7,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](OCCCCOC(=O)CCl)C[C@]4(C)[C@H]3C(=O)C[C@]12C>>CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](OCCCCO)C[C@]4(C)[C@H]3C(=O)C[C@]12C -US06590118B1,6,CC(=O)Nc1ccccc1Oc1ccc(-c2nnnn2Cc2ccccc2)c(-c2nnnn2Cc2ccccc2)c1>>Nc1ccccc1Oc1ccc(-c2nnnn2Cc2ccccc2)c(-c2nnnn2Cc2ccccc2)c1 -US20120101131A1,2,CCOC(=O)Cn1ncc2c1CCCC2NS(=O)(=O)c1cccc(N)c1.O=C(Cl)c1ccccc1>>CCOC(=O)Cn1ncc2c1CCCC2NS(=O)(=O)c1cccc(NC(=O)c2ccccc2)c1 -US04413144,3,CC(C)c1ccccc1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC(C)c1ccc(C(=O)c2ccc([N+](=O)[O-])cc2)cc1 -US08785436B2,8,N#Cc1cnc2c(c1)CCCC2O>>N#Cc1cnc2c(c1)CCCC2=O -US08158622B2,6,COc1ccc(C2(CNC(=O)c3cc4cc(Cl)ncc4[nH]3)OCCO2)cc1>>COc1ccc(C(=O)CNC(=O)c2cc3cc(Cl)ncc3[nH]2)cc1 -US20140005213A1,4,C/C=C/C=O.Nc1ccc(F)c(Br)c1>>Cc1ccc2cc(F)c(Br)cc2n1 -US06818774B2,2,COC(=O)Cc1cc(OCc2ccc(F)cc2)ccc1CN[C@@H](C)C(N)=O>>C[C@@H](C(N)=O)N1Cc2ccc(OCc3ccc(F)cc3)cc2CC1=O -US20140364433A1,9,Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc3c(Br)cccc3n2)c1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc3ccccc3n2)c1 -US07517992B2,7,Nc1ccc(C(=O)c2ccc(F)cc2)cn1>>Nc1ccc(Cc2ccc(F)cc2)cn1 -US07713994B2,7,CN1CCN(c2ccc([N+](=O)[O-])c(O)n2)CC1>>CN1CCN(c2ccc(N)c(O)n2)CC1 -US05481034,8,CC1=CC(=O)CC(C)(C(F)(F)F)C1O>>CC1=CC(=O)CC(C)(C(F)(F)F)C1=O -US20050203160A1,6,CCOC(=O)Cn1ccc2ccc(OCc3cc(-c4ccc(OC(F)(F)F)cc4)n(C)n3)cc21>>Cn1nc(COc2ccc3ccn(CC(=O)O)c3c2)cc1-c1ccc(OC(F)(F)F)cc1 -US05319092,6,CCOC(=O)CSc1nc(C(C)(C)C)nn1C(=O)N(C)C>>CN(C)C(=O)n1nc(C(C)(C)C)nc1SCC(=O)O -US20070281955A1,6,COc1cccc(-c2nc3sccn3c2-c2ccnc(N[C@@H]3CCCN(S(=O)(=O)c4ccc(Cl)cc4)C3)n2)c1>>O=S(=O)(c1ccc(Cl)cc1)N1CCC[C@@H](Nc2nccc(-c3c(-c4cccc(O)c4)nc4sccn34)n2)C1 -US20110118234A1,9,Cc1cc(-c2ccc(NC(=O)NCCc3ccc(Br)cc3)cc2)ccn1.[C-]#N>>Cc1cc(-c2ccc(NC(=O)NCCc3ccc(C#N)cc3)cc2)ccn1 -US07863332B2,1,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1.CCI>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCC)c1 -US05885979,1,CCI.CCOC(=O)C[C@H]1O[C@H](c2ccc(O)cc2OC)c2cc(Cl)ccc2N(CC(C)(C)C)C1=O>>CCOC(=O)C[C@H]1O[C@H](c2ccc(OCC)cc2OC)c2cc(Cl)ccc2N(CC(C)(C)C)C1=O -US07153854B2,9,CCOC(=O)CCCCc1c(C)nn2c(CC)ccc2c1-c1cncc(Br)c1.N#C[Cu]>>CCOC(=O)CCCCc1c(C)nn2c(CC)ccc2c1-c1cncc(C#N)c1 -US08426447B2,3,COC(C)(C)C#Cc1ccc2c(c1)C1(COC(N)=N1)c1cc(Br)cnc1O2.OB(O)c1cccnc1>>COC(C)(C)C#Cc1ccc2c(c1)C1(COC(N)=N1)c1cc(-c3cccnc3)cnc1O2 -US20100063068A1,2,CC(C)(C)N.CNC(=O)c1c(-c2ccc(F)cc2)oc2ncc(-c3cccc(C(=O)O)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ncc(-c3cccc(C(=O)NC(C)(C)C)c3)cc12 -US05811548,6,COc1ccc2c(c1CC#N)Oc1c(ccc(OC)c1CN1C(=O)c3ccccc3C1=O)N2C>>COc1ccc2c(c1CN)Oc1c(ccc(OC)c1CC#N)N2C -US20140303149A1,6,CC(=O)Nc1ccc([N+](=O)[O-])c(OC(C)=O)c1>>CC(=O)Nc1ccc([N+](=O)[O-])c(O)c1 -US20120035370A1,6,CCC(NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)C1CCCN(C(=O)OC(C)(C)C)C1>>CCC(NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)C1CCCNC1 -US20100298287A1,1,CC(C)[O-].Cc1nc(Cl)nc(C)c1N1CCCn2c1nc1c(Cl)ccc(C(OC(F)F)C(F)(F)F)c12>>Cc1nc(OC(C)C)nc(C)c1N1CCCn2c1nc1c(Cl)ccc(C(OC(F)F)C(F)(F)F)c12 -US05166218,3,CC(=O)c1ccc(CC(C)O)s1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C(\C)c1ccc(CC(C)O)s1 -USRE037094E1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)c1cc2ccccc2[nH]1>>CC(C)(C)OC(=O)n1c(C(=O)O)cc2ccccc21 -US20100280067A1,1,CC(=O)NC(C)c1ccc2c(c1)CCNC2.Cc1cc(OC(C)C)ccc1CBr>>CC(=O)NC(C)c1ccc2c(c1)CCN(Cc1ccc(OC(C)C)cc1C)C2 -US05756508,1,CC1CN(Cc2ccccc2)CCC1=O.CI>>CC1C[N+](C)(Cc2ccccc2)CCC1=O -US20100256356A1,1,CN(C(=O)OC(C)(C)C)C1CCNCC1.COc1ccc(Cn2nc(I)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(N3CCC(N(C)C(=O)OC(C)(C)C)CC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1 -US20060252797A1,2,CC(=O)Cl.Cc1csc(C2(Nc3ccccc3)CCN(C(C)(C)c3ccccc3)CC2)n1>>CC(=O)N(c1ccccc1)C1(c2nc(C)cs2)CCN(C(C)(C)c2ccccc2)CC1 -US20020026060A1,1,CC(C)(CO)c1ccc2c(c1)C(C)(C)CCC2(C)C.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCC(C)(C)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 -US08106236B2,3,COC(=O)C(CC(C)C)c1cc(OS(=O)(=O)C(F)(F)F)cc(-c2cc(F)cc(C(F)(F)F)c2)c1.OB(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COC(=O)C(CC(C)C)c1cc(-c2cc(F)cc(C(F)(F)F)c2)cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 -US20070129371A1,6,COC(=O)[C@H](CNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC[C@H](NC(=O)OCc1ccccc1)C(=O)O -US05521173,2,O=C(Cl)c1ccc(C(=O)c2ccccc2)cc1.c1ccc2c(c1)Cn1cccc1CN2>>O=C(c1ccccc1)c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 -US20110201599A1,3,CC(=O)Cl.Clc1ccnc2[nH]ccc12>>CC(=O)c1c[nH]c2nccc(Cl)c12 -US06436918B1,7,CC(C)(C)NC(=O)C1=CC[C@H]2[C@@H]3CCc4cc(OS(N)(=O)=O)ccc4[C@H]3CC[C@]12C>>CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CCc4cc(OS(N)(=O)=O)ccc4[C@H]3CC[C@]12C -US20150099737A1,1,CC(C)(C)OC(=O)N1CCC[C@]2(C1)CN(c1ccc(N)nc1)C(=O)O2.CN(C)C(=O)c1cc2cnc(Cl)nc2n1C1CCCC1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(N4C[C@@]5(CCCN(C(=O)OC(C)(C)C)C5)OC4=O)cn3)nc2n1C1CCCC1 -US20150209445A1,6,CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(OCc1ccccc1)c1ccccc21>>CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21 -US20140235636A1,6,CC(C)(C)OC(=O)N(OC(=O)C(C)(C)C)S(=O)(=O)c1cccnc1>>CC(C)(C)C(=O)ONS(=O)(=O)c1cccnc1 -US06437184B1,6,CCOC(COCCCCOc1c(CC)cc(OCC=C(Cl)Cl)cc1CC)OCC>>CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCCOCC=O -US20060167023A1,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.Fc1ccc(COc2ccc3c(c2)CCNC3)cc1>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2cc(OCc3ccc(F)cc3)ccc2C1 -US05736534,1,COc1cc2ncnc(Cl)c2cc1OC.c1c2c(cc3c1NCC3)NCC2>>COc1cc2ncnc(N3CCc4cc5c(cc43)CCN5)c2cc1OC -US05576324,7,Cc1cc2c(c3ccc(=O)[nH]c13)OC(CO)C2>>Cc1cc2c(c3c1NC(=O)CC3)OC(CO)C2 -US20020099212A1,1,NCc1ccc(Cl)cc1Cl.O=C(O)c1ccc([N+](=O)[O-])c(F)c1>>O=C(O)c1ccc([N+](=O)[O-])c(NCc2ccc(Cl)cc2Cl)c1 -US09062048B2,7,O=C1C=CC(C2CCC3(CC2)OCCO3)N1>>O=C1CCC(C2CCC3(CC2)OCCO3)N1 -US20090012290A1,1,O=[N+]([O-])c1ccc(F)c(Cl)c1.OCc1cccc(F)c1>>O=[N+]([O-])c1ccc(OCc2cccc(F)c2)c(Cl)c1 -US20040235823A1,6,CN1CCCc2cccc(NC(=O)OC(C)(C)C)c21>>CN1CCCc2cccc(N)c21 -US20140010783A1,7,N#Cc1ccc([N+](=O)[O-])cc1C1CC1>>N#Cc1ccc(N)cc1C1CC1 -US07989438B2,3,COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1.COc1ccc(B(O)O)c(CO[Si](C(C)C)(C(C)C)C(C)C)c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(OC)cc3CO[Si](C(C)C)(C(C)C)C(C)C)[nH]c2c1 -US06350751B1,2,CCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1C(=O)O.CCc1c(N)c(C(N)=O)nn1Cc1ccccn1>>CCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1C(=O)Nc1c(C(N)=O)nn(Cc2ccccn2)c1CC -US20100273832A1,9,NO.O=Cc1ccc(Br)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(C=NO)ccc1Br -US08828987B2,2,COC(=O)c1ccc(C2(N)CC2)cc1.O=C(O)c1cc(Cl)cnc1N1CC(Nc2cccc(C(F)(F)F)c2)C1>>COC(=O)c1ccc(C2(NC(=O)c3cc(Cl)cnc3N3CC(Nc4cccc(C(F)(F)F)c4)C3)CC2)cc1 -US20140057896A1,7,CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)C(=O)C1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)nc2)C(=O)C1 -US07560558B2,1,COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCCl.N=C(N)N>>COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCNC(=N)N -US20110028514A1,2,CC(C)CNc1ccc2nc(S)sc2c1.O=C=Nc1ccc(C(F)(F)F)cc1>>CC(C)CN(C(=O)Nc1ccc(C(F)(F)F)cc1)c1ccc2nc(S)sc2c1 -US05834501,1,BrCCC1OCCO1.O=C1NC(=O)C(Cc2ccc(O)cc2)S1>>O=C1NC(=O)C(Cc2ccc(OCCC3OCCO3)cc2)S1 -US05424333,6,CC(C)(C)OC(=O)NN(C(=O)c1ccccc1)C(C)(C)C>>CC(C)(C)N(N)C(=O)c1ccccc1 -US08188113B2,3,COC(=O)c1cnc(C(C)(C)C)nc1Cl.Cn1ccc2cc(B(O)O)ccc21>>COC(=O)c1cnc(C(C)(C)C)nc1-c1ccc2c(ccn2C)c1 -US07375227B2,6,Cc1ccc(C2(O)CCN(Cc3ccccc3)CC2)cc1>>Cc1ccc(C2(O)CCNCC2)cc1 -US04521417,2,CN1CCNCC1.COC(=O)CC/C=C(\C)CCC=C(C)CC/C=C(\C)CCC=C(C)C>>CC(C)=CCC/C(C)=C/CCC(C)=CCC/C(C)=C/CCC(=O)N1CCN(C)CC1 -US20120046292A1,1,CCOC(=O)[C@@H]1CC[C@H](O)CC1.Oc1cccc(F)c1>>CCOC(=O)[C@@H]1CC[C@@H](Oc2cccc(F)c2)CC1 -US20110281854A1,1,CC1CNC(c2cccc(F)c2)CO1.O=C1COc2ccc(Br)nc2N1>>C[C@H]1CN(c2ccc3c(n2)NC(=O)CO3)[C@@H](c2cccc(F)c2)CO1 -US20100093675A1,7,CCOC(=O)C1CC1(CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@@]21C>>CC(C)(O)CCCC1([C@H]2CC[C@H]3[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@@]32C)CC1CO -US08653091B2,9,[N-]=[N+]=NC(CCO)c1ccc(C(F)(F)F)nc1>>NC(CCO)c1ccc(C(F)(F)F)nc1 -US20080242663A1,1,BrCc1ccccc1.O=[N+]([O-])c1cc(O)cc(N2CCOCC2)c1>>O=[N+]([O-])c1cc(OCc2ccccc2)cc(N2CCOCC2)c1 -US08106215B2,5,CC1C[C@H]2CN(C(=O)OC(C)(C)C)[C@H](CN)[C@H]2C1.CCOC(=O)C(F)(F)F>>CC1C[C@H]2CN(C(=O)OC(C)(C)C)[C@H](CNC(=O)C(F)(F)F)[C@H]2C1 -US06924292B2,3,COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(Br)c1)=NC(C)(C)C2.OB(O)c1ccccc1>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(-c3ccccc3)c1)=NC(C)(C)C2 -US20130261132A1,6,CCOC(=O)COc1ccc([C@@H]2CCC(=O)C2)cc1>>O=C(O)COc1ccc([C@@H]2CCC(=O)C2)cc1 -US20070287725A1,2,CC(C)(C)OC(=O)NCCNc1c(N)c(Cl)nc2ccccc12.CCOCC(=O)Cl>>CCOCC(=O)Nc1c(Cl)nc2ccccc2c1NCCNC(=O)OC(C)(C)C -US08952169B2,2,CNS(N)(=O)=O.N#CC1(COc2cc(F)c(C(=O)O)cc2Cl)C2CC3CC(C2)CC1C3>>CNS(=O)(=O)NC(=O)c1cc(Cl)c(OCC2(C#N)C3CC4CC(C3)CC2C4)cc1F -US04410548,8,COc1cc(SC)c(C)cc1O.OO>>COc1cc(S(C)=O)c(C)cc1O -US20100184758A1,6,CC(C)(C)OC(=O)N1C(c2nc(-c3ccc(F)cc3)c[nH]2)Cc2c([nH]c3ccc(-n4cccn4)cc23)C1C1CCOCC1>>Fc1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccc(-n6cccn6)cc45)C(C4CCOCC4)N3)n2)cc1 -US20110281884A1,6,CC(=O)c1cc(Cl)c2cncn2c1N1CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)c1cc(Cl)c2cncn2c1N1CCNCC1 -US06632820B1,1,Cc1ccc(Cl)c(N)c1.Clc1cc(Cl)ncn1>>Cc1ccc(Cl)c(Nc2cc(Cl)ncn2)c1 -US20080132509A1,1,CC1CCCN1c1nc(-c2ccc(F)cc2)cc(-c2ccc(F)nc2)n1.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(c2ccc(-c3cc(-c4ccc(F)cc4)nc(N4CCCC4C)n3)cn2)CC1 -US20080090834A1,1,Cc1ccc(-n2cc(-c3ccccn3)nc2-c2ccc(I)cc2)cn1.Cc1cnc2[nH]ccc2c1>>Cc1cnc2c(ccn2-c2ccc(-c3nc(-c4ccccn4)cn3-c3ccc(C)nc3)cc2)c1 -US20050131014A1,1,N#Cc1ccc(C#N)c(CBr)c1.Oc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>N#Cc1ccc(C#N)c(COc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 -US20120122972A1,3,C#CCCCCCCCCCCCCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.C=O>>CC(C)(C)[Si](OCCCCCCCCCCCCCC#CCO)(c1ccccc1)c1ccccc1 -US20090221635A1,1,Clc1nc2c(Cl)cccc2s1.Nc1cc(Cl)c(O)c(Cl)c1>>Nc1cc(Cl)c(Oc2nc3c(Cl)cccc3s2)c(Cl)c1 -US20040147561A1,6,CCOC(=O)c1cc(-c2csc(-c3ccncc3)n2)c(=O)[nH]c1CCOCc1ccccc1>>CCOC(=O)c1cc(-c2csc(-c3ccncc3)n2)c(=O)[nH]c1CCO -US08901156B2,2,CC(C)(CN)c1nc(-c2ccc(F)cc2)n[nH]1.O=C(O)c1cncc(-c2noc(C(F)(F)F)n2)c1>>CC(C)(CNC(=O)c1cncc(-c2noc(C(F)(F)F)n2)c1)c1nc(-c2ccc(F)cc2)n[nH]1 -US20100048597A1,1,Clc1nccc(-c2cccnc2Cl)n1.Nc1cccc(Cl)c1>>Clc1cccc(Nc2nccc(-c3cccnc3Cl)n2)c1 -US20070244153A1,2,CC(C)[C@H](N)CNC(=O)c1cc2ccccc2o1.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CC(C)[C@@H](CNC(=O)c1cc2ccccc2o1)NC(=O)[C@H](C)NC(=O)OC(C)(C)C -US20040097498A1,6,CCOc1ccc(OCc2ccccc2)cc1C#N>>CCOc1ccc(O)cc1C#N -US04211709,1,CC(=O)c1c(C)[nH]c(-c2ccccc2)c1N(C)C.ClCc1ccccc1Cl>>CC(=O)c1c(N(C)C)c(-c2ccccc2)n(Cc2ccccc2Cl)c1C -US07576221B2,6,O=C(C[C@@H](CF)N1C(=O)c2ccccc2C1=O)OCc1ccccc1>>O=C(O)C[C@@H](CF)N1C(=O)c2ccccc2C1=O -US20020198194A1,1,C1CCNC1.Cc1cc(N2CCCC2)c2ccc(OCc3ccc(Cl)nc3)cc2n1>>Cc1cc(N2CCCC2)c2ccc(OCc3ccc(N4CCCC4)nc3)cc2n1 -US04904674,3,Brc1ccc(C=Cc2csc3ccccc23)s1.CI>>Cc1ccc(C=Cc2csc3ccccc23)s1 -US08372864B2,1,CCCC(=O)CCC.NCCc1ccccc1Br>>CCCC(CCC)NCCc1ccccc1Br -US08163909B2,6,COC(=O)[C@H](Cc1ccc(C(F)(F)F)cc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@@H](Cc1ccc(C(F)(F)F)cc1)C(=O)O -US20020016337A1,1,CC(C)(C)OC(=O)N1CCCC(C=O)C1.Nc1cccnc1>>CC(C)(C)OC(=O)N1CCCC(CNc2cccnc2)C1 -US20090111861A1,2,Cc1cc(C(=O)Cl)ccc1[N+](=O)[O-].NC1CC1>>Cc1cc(C(=O)NC2CC2)ccc1[N+](=O)[O-] -US20080221178A1,7,O=[N+]([O-])c1cc(NS(=O)(=O)c2ccccc2)ccc1NCC1CCCO1>>Nc1cc(NS(=O)(=O)c2ccccc2)ccc1NCC1CCCO1 -US09073922B2,1,Nc1ccc(Cl)c(Br)n1.O=Cc1ccccc1>>Clc1ccc(NCc2ccccc2)nc1Br -US20050154056A1,2,COC(=O)Cc1c[nH]cn1.NN>>NNC(=O)Cc1c[nH]cn1 -US20150152092A1,6,COC(=O)c1cc(-c2c(C)cnn2C)c(C)o1>>Cc1cnn(C)c1-c1cc(C(=O)O)oc1C -US20090048258A1,6,CCOC(=O)/C=C/c1cc(C(=O)CCC(=O)Nc2nc(-c3ccccc3)c(Cc3ccccc3)s2)ccc1OCC>>CCOc1ccc(C(=O)CCC(=O)Nc2nc(-c3ccccc3)c(Cc3ccccc3)s2)cc1/C=C/C(=O)O -US04572914,2,Clc1ccc(C2=NNCC2c2ccccc2)cc1.O=C=Nc1ccc(OC(F)(F)C(F)F)cc1>>O=C(Nc1ccc(OC(F)(F)C(F)F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 -US04107329,1,C=[N+]=[N-].O=C(O)C(Oc1ccc(Cl)cc1)(C(F)(F)F)C(F)(F)F>>COC(=O)C(Oc1ccc(Cl)cc1)(C(F)(F)F)C(F)(F)F -US20100016368A1,6,CCOC(=O)Cn1ncc2c1CCC[C@H]2NC(=O)OCc1ccccc1>>CCOC(=O)Cn1ncc2c1CCC[C@H]2N -US07053070B2,9,CSc1ncc2ccc(Cl)nc2n1.N>>CSc1ncc2ccc(N)nc2n1 -US07414036B2,7,CC(=O)OCc1cc(I)ccn1>>OCc1cc(I)ccn1 -US06432975B1,7,O=C(O)c1cncc(Br)c1>>OCc1cncc(Br)c1 -US05668147,6,CC(C)(C)OC(=O)NC[C@@H]1CNC[C@H]1C(F)(F)F>>NC[C@@H]1CNC[C@H]1C(F)(F)F -US05654301,2,CC(=O)NC(C(=O)O)C1(C)CC=CO1.NCc1ccccc1>>CC(=O)NC(C(=O)NCc1ccccc1)C1(C)CC=CO1 -US08785653B2,7,CCOC(=O)Cn1nc(-c2ccccc2)nc1CCc1nc2c(OC)ccc(C)n2n1>>COc1ccc(C)n2nc(CCc3nc(-c4ccccc4)nn3CCO)nc12 -US08022062B2,3,CC(C)(C)C[Mg+].CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCc3ccc(Br)cn3)c2CC1>>CC(C)(C)Cc1ccc(CSc2c(Cl)ccc3c2CCN(C(=O)OC(C)(C)C)CC3)nc1 -US20060276498A1,1,N#Cc1cnc2cnc(F)cc2c1Cl.Nc1cccc(Oc2ccccc2)c1>>N#Cc1cnc2cnc(F)cc2c1Nc1cccc(Oc2ccccc2)c1 -US20100094000A1,1,CC(C)(C)OC(=O)NN.O=Cc1ccccn1>>CC(C)(C)OC(=O)NN=Cc1ccccn1 -US04153607,4,Cc1nc(N)c(C(N)=S)s1>>Cc1nc2nsc(N)c2s1 -US05059689,1,CC(=O)N1C(C)(C)CC(O)CC1(C)C.CC1(C)CC(Oc2nc(Cl)nc(N3C(C)(C)CCCC3(C)C)n2)CC(C)(C)N1O>>CC(=O)N1C(C)(C)CC(Oc2nc(OC3CC(C)(C)N(O)C(C)(C)C3)nc(N3C(C)(C)CCCC3(C)C)n2)CC1(C)C -US20120208798A1,3,CC(=O)N1c2ccc(B3OC(C)(C)C(C)(C)O3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.CC(C)(C)OC(=O)NCCn1cnc(I)c1>>CC(=O)N1c2ccc(-c3cn(CCNC(=O)OC(C)(C)C)cn3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C -US20070032526A1,6,CCC(O)[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@H](NC(=O)OCc2ccccc2)C1=O>>CCC(O)[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@H](N)C1=O -US20110237571A1,6,CC(C)(C)OC(=O)Nc1cc(-c2cccc(O)c2)ccc1Cl>>Nc1cc(-c2cccc(O)c2)ccc1Cl -US04870098,2,CCOC(=O)CC1CCC2(C1)OCC(CO)O2.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)CC1CCC2(C1)OCC(COS(=O)(=O)c1ccc(C)cc1)O2 -US20140005188A1,6,CC(C)(C)OC(=O)N1CCC[C@H](CNc2nc(-c3cnn(C4CCCC4)c3)cc3nccnc23)C1>>c1cnc2c(NC[C@H]3CCCNC3)nc(-c3cnn(C4CCCC4)c3)cc2n1 -US20120189546A1,1,Brc1ccc(OCc2ccccc2)cc1.C1CNCCN1>>c1ccc(COc2ccc(N3CCNCC3)cc2)cc1 -US08513269B2,2,CNC.CNc1nc(-c2cccc(NC(=O)c3ccc(C(=O)O)cc3)c2)c2cc(OC)c(OC)cc2n1>>CNc1nc(-c2cccc(NC(=O)c3ccc(C(=O)N(C)C)cc3)c2)c2cc(OC)c(OC)cc2n1 -US06897231B2,6,O=C(Nc1ccc(OCc2ccccc2)cc1C(=O)c1ccccc1)c1ccccc1>>Nc1ccc(OCc2ccccc2)cc1C(=O)c1ccccc1 -US20150197530A1,2,CCN.O=C(O)Cc1ccsc1-c1ccc(Cl)cc1>>CCNC(=O)Cc1ccsc1-c1ccc(Cl)cc1 -US05883262,1,Fc1ccccn1.OCCOc1ccc(Cn2cccn2)cc1Cl>>Clc1cc(Cn2cccn2)ccc1OCCOc1ccccn1 -US20050277627A1,6,COC(=O)c1ccc(NC(=O)CCN2CCN(C)CC2)cc1>>CN1CCN(CCC(=O)Nc2ccc(C(=O)O)cc2)CC1 -US20080234262A1,3,CC(C)(C)OC(=O)N1CCC(n2ncc3c(N4CCOCC4)nc(Cl)nc32)CC1.CC1(C)OB(c2ccc([N+](=O)[O-])cc2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(N4CCOCC4)nc(-c4ccc([N+](=O)[O-])cc4)nc32)CC1 -US08623866B2,2,COC(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1.OC1CCNC1>>Cn1cc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)c(C(=O)N2CCC(O)C2)n1 -US20130331396A1,1,O=C(Nc1ccccc1)N1CCNCC1.O=C1CCc2cc(Br)ccc2C1>>O=C(Nc1ccccc1)N1CCN(C2CCc3cc(Br)ccc3C2)CC1 -US20030130186A1,1,BrCc1ccccc1.O=C(O)CCCCCCCCCCCO>>O=C(CCCCCCCCCCCO)OCc1ccccc1 -US20100029636A1,6,CC(C)COC(=O)Nc1ccc(-c2cnc3c(-c4ccc(N5CCN(C(=O)OCc6ccccc6)CC5)cc4)cnn3c2N)cc1>>CC(C)COC(=O)Nc1ccc(-c2cnc3c(-c4ccc(N5CCNCC5)cc4)cnn3c2N)cc1 -US20120149721A1,3,COC(=O)c1c(C)n(COCC[Si](C)(C)C)c2c(Cl)nc(C)nc12.COc1cc(B2OC(C)(C)C(C)(C)O2)c(OCC2CC2)cc1F>>COC(=O)c1c(C)n(COCC[Si](C)(C)C)c2c(-c3cc(OC)c(F)cc3OCC3CC3)nc(C)nc12 -US20080269255A1,2,COCCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>COCCCOS(=O)(=O)c1ccc(C)cc1 -US20130345123A1,6,O=C(N[C@H]1CCS[C@H]2CCCCN2C1=O)OCc1ccccc1>>N[C@H]1CCS[C@H]2CCCCN2C1=O -US07645751B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1c(F)cc(CN)cc1F>>CC(C)(C)OC(=O)NCc1cc(F)c(C#N)c(F)c1 -US08889878B2,2,NC1CC1.O=C(O)c1ccc2cc(C(=O)NC(c3cccc(C(F)(F)F)c3)C(F)(F)F)oc2c1>>O=C(NC1CC1)c1ccc2cc(C(=O)NC(c3cccc(C(F)(F)F)c3)C(F)(F)F)oc2c1 -US20140315898A1,2,NCC(F)F.O=C(Cl)C1CC1>>O=C(NCC(F)F)C1CC1 -US06350907B1,6,Cc1cc(CCC[C@H](CC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@H](C)c2ccccc2)C(C)(C)C)ccc1Oc1ccccc1>>Cc1cc(CCC[C@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C)c2ccccc2)C(C)(C)C)ccc1Oc1ccccc1 -US20150152108A1,3,CC1(C)OB(c2cccc(N3CC[C@@H](F)C3)c2)OC1(C)C.O=C(Nc1cnccn1)N1c2nc(Cl)ccc2N2CC[C@H]1C2>>O=C(Nc1cnccn1)N1c2nc(-c3cccc(N4CC[C@@H](F)C4)c3)ccc2N2CC[C@H]1C2 -US20130172550A1,7,N#Cc1cccc(Nc2ccc3c(c2[N+](=O)[O-])CCC3)c1>>N#Cc1cccc(Nc2ccc3c(c2N)CCC3)c1 -US20140094465A1,3,O=C(O)c1ccc(B(O)O)cc1.Oc1ccc2cc(Br)c(O)cc2c1>>O=C(O)c1ccc(-c2cc3ccc(O)cc3cc2O)cc1 -US07253198B2,6,COC(=O)c1cc(NC(=O)OC(C)(C)C)cc(SC)c1>>COC(=O)c1cc(N)cc(SC)c1 -US20150232435A1,2,Cc1cc(N2CCN(CCCCN)CC2)nc(C(C)(C)C)n1.O=C(O)c1cn2ccccc2n1>>Cc1cc(N2CCN(CCCCNC(=O)c3cn4ccccc4n3)CC2)nc(C(C)(C)C)n1 -US20100197681A1,3,COc1cccc(B(O)O)c1.O=C(Nc1nc2ccc(Br)cn2n1)c1cccnc1>>COc1cccc(-c2ccc3nc(NC(=O)c4cccnc4)nn3c2)c1 -US04255426,1,C=CCBr.CCCCCCCCCCCCCCCCO>>C=CCOCCCCCCCCCCCCCCCC -US20140171407A1,3,Nc1cnc(Cl)c(F)c1I.OB(O)c1cccnc1F>>Nc1cnc(Cl)c(F)c1-c1cccnc1F -US04076821,1,O=C1CCC(c2ccc(F)cc2)(c2ccc(F)cc2)CC1.OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCNCC1>>OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(C2CCC(c3ccc(F)cc3)(c3ccc(F)cc3)CC2)CC1 -US07985755B2,1,N#Cc1c(F)cccc1F.OCC1CCC(Cc2ccccc2F)CC1>>N#Cc1c(F)cccc1OCC1CCC(Cc2ccccc2F)CC1 -US20120295903A1,1,BrCCCc1cccnc1.Cc1cc(N)c([N+](=O)[O-])cc1C>>Cc1cc(NCCCc2cccnc2)c([N+](=O)[O-])cc1C -US20070054916A1,2,Cc1cc(C)c(Br)c(C)c1N.O=C(Cl)c1cccc(C(F)(F)F)c1>>Cc1cc(C)c(NC(=O)c2cccc(C(F)(F)F)c2)c(C)c1Br -US20130172384A1,3,COc1ccc(B(O)O)c(Cl)c1.Cn1nc(-c2ccc(Br)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O>>COc1ccc(-c2ccc(-c3nn(C)c(=O)n3C[C@@H]3CCN(C(=O)C4CC4)C3)cc2)c(Cl)c1 -US08536165B2,3,Brc1ccc(Br)nc1.CCOc1cccc(B(O)O)c1F>>CCOc1cccc(-c2ccc(Br)cn2)c1F -US20080306052A1,7,O=C1SCC(c2ccc(Cl)cc2)=NN1Cc1cccc([N+](=O)[O-])c1>>Nc1cccc(CN2N=C(c3ccc(Cl)cc3)CSC2=O)c1 -US05137653,9,Oc1ccc(-c2ccccc2)cc1>>c1ccc(-c2ccccc2)cc1 -US05889012,7,CC1(C2CCC(=O)CC2)CC1>>CC1([C@@H]2CC[C@H](O)CC2)CC1 -US08415368B2,2,CSc1ccccc1-c1cc(C=O)c[nH]1.O=S(=O)(Cl)c1cccnc1>>CSc1ccccc1-c1cc(C=O)cn1S(=O)(=O)c1cccnc1 -US20100120793A1,1,CCOC(=O)C1(CI)CCN(C(=O)c2ccccc2OC)C1.Oc1ccc(-c2ccc(F)cc2)nc1>>CCOC(=O)C1(COc2ccc(-c3ccc(F)cc3)nc2)CCN(C(=O)c2ccccc2OC)C1 -US08334301B2,1,O=Cc1cc(-c2cccnc2F)c(Br)s1.Sc1nccs1>>O=Cc1cc(-c2cccnc2F)c(Sc2nccs2)s1 -US04030925,7,O=C(NNc1ccc([N+](=O)[O-])cc1)c1ccc(Cl)cc1>>Nc1ccc(NNC(=O)c2ccc(Cl)cc2)cc1 -US20090018134A1,2,Cc1nnc(S(=O)(=O)C2(c3cc(N4CCOC[C@@H]4C)nc(-c4ccc(N)cc4)n3)CC2)s1.O=C(Cl)Oc1ccccc1>>Cc1nnc(S(=O)(=O)C2(c3cc(N4CCOC[C@@H]4C)nc(-c4ccc(NC(=O)Oc5ccccc5)cc4)n3)CC2)s1 -US07977343B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@H]1C[C@H](O)CN1>>CCOC(=O)[C@H]1C[C@H](O)CN1C(=O)OC(C)(C)C -US20040242564A1,6,COc1cc2c(cc1C(=O)N(C)C)C(Cc1ccc(Cl)c(Cl)c1)N(C(=O)OC(C)(C)C)CC2>>COc1cc2c(cc1C(=O)N(C)C)C(Cc1ccc(Cl)c(Cl)c1)NCC2 -US06852726B2,7,COC(=O)Cc1[nH]c2ccc(Cl)cc2c1SC>>CSc1c(CCO)[nH]c2ccc(Cl)cc12 -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)Nc2ncc(Cl)cc2Cl)cc1.FC(F)(F)c1cc(Cl)ccc1CBr>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(Cl)cc2C(F)(F)F)c2ncc(Cl)cc2Cl)cc1 -US20090275573A1,1,CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1C=O.Nc1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1CNc1cccc(Cl)c1 -US20110118262A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)C1.N#Cc1ccc(Br)c(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CC=C(c2ccc(C#N)cc2C(F)(F)F)C1 -US20110189167A1,3,C=C(C)B1OC(C)(C)C(C)(C)O1.Nc1cncc(Br)c1>>C=C(C)c1cncc(N)c1 -US06127541,1,CN1CCCNCC1.N#Cc1ccccc1F>>CN1CCCN(c2ccccc2C#N)CC1 -US20030149104A1,1,CCOC(=O)C(Cc1ccc(O)c(C(C)(C)C)c1)OCC.CS(=O)(=O)OCCc1ccc(OS(C)(=O)=O)cc1>>CCOC(=O)C(Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)c(C(C)(C)C)c1)OCC -US05753665,1,CC(Br)c1ccnc2ncnn12.CSc1ccc(O)cc1>>CSc1ccc(OC(C)c2ccnc3ncnn23)cc1 -US20150225367A1,6,CC(C)(C)OC(=O)NCC(=O)N1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1>>NCC(=O)N1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1 -US20120149912A1,7,O=Cc1nn(Cc2ccccc2)c2ccccc12>>OCc1nn(Cc2ccccc2)c2ccccc12 -US07094798B1,3,COc1ccc2[nH]c(C=O)cc2c1.O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)OCc1ccccc1>>COc1ccc2[nH]c(/C=C/C(=O)OCc3ccccc3)cc2c1 -US20120189568A1,2,Nc1ccc(O)c(C(=O)O)c1.O=C(O)C1CCCCC1>>O=C(O)c1cc(NC(=O)C2CCCCC2)ccc1O -US04668274,1,BrCCBr.Cc1cc(=O)oc2cc(O)ccc12>>Cc1cc(=O)oc2cc(OCCBr)ccc12 -US05389647,3,CCCC[Mg+].O=Cc1ccco1>>CCCCC(O)c1ccco1 -US06608080B1,1,C1CC2CCNC(C1)C2.C=CCBr>>C=CCN1CCC2CCCC1C2 -US20020049316A1,1,CNC.COC(=O)c1ccc(CBr)cc1>>COC(=O)c1ccc(CN(C)C)cc1 -US08802684B2,9,BrC(Br)(Br)Br.O=C(OCc1ccccc1)N1CCCCC1CCO>>O=C(OCc1ccccc1)N1CCCCC1CCBr -US04112095,7,Cc1cc2nncn2nc1-c1cccc([N+](=O)[O-])c1>>Cc1cc2nncn2nc1-c1cccc(N)c1 -US20100144722A1,1,C1CC1CNCC1CC1.Fc1ccc(-c2cc(Cl)nc(Cl)n2)cc1>>Fc1ccc(-c2cc(N(CC3CC3)CC3CC3)nc(Cl)n2)cc1 -US20150111877A1,6,Cc1cccc(S(=O)(=O)N2CCCc3ncc(NC(=O)OC(C)(C)C)cc32)c1>>Cc1cccc(S(=O)(=O)N2CCCc3ncc(N)cc32)c1 -US20110263571A1,2,CC(C)[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1.Cc1ccc(N2CCNCC2)nc1>>Cc1ccc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C(C)C)cc3)CC2)nc1 -US20140296208A1,1,CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(Cl)n2)c2ccccc12.COCCOCCOCCOc1cc(N)cc(OC)c1>>COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)OC(C)(C)C)c4ccccc34)n2)cc(OC)c1 -US20100069350A1,2,CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1C(F)(F)F.NS(=O)(=O)Cc1cccc(Cl)c1>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)Cc3cccc(Cl)c3)C2)nc1C(F)(F)F -US20150087658A1,6,C[C@H](NC(=O)OC(C)(C)C)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1>>C[C@H](N)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 -US20130217666A1,3,CC1(C[Zn+])COC1.COC(=O)c1nc2n(c1I)C1CC(C1)c1ccc(Br)cc1-2>>COC(=O)c1nc2n(c1CC1(C)COC1)C1CC(C1)c1ccc(Br)cc1-2 -US20020066886A1,1,CCC/C=C/CO.N#Cc1ccc(-c2ccc(O)cc2)cc1>>CCC/C=C/COc1ccc(-c2ccc(C#N)cc2)cc1 -US04923970,9,CC(=O)N(C)N=NCCO.ClC(Cl)(Cl)Cl>>CC(=O)N(C)N=NCCCl -US20080132477A1,7,CC(C)(C)c1cccc(C#N)c1>>CC(C)(C)c1cccc(CN)c1 -US20060074102A1,1,NC(=O)c1cc2c(-c3ccc(NC(=O)CCl)cc3)cncc2s1.c1cn[nH]c1>>NC(=O)c1cc2c(-c3ccc(NC(=O)Cn4cccn4)cc3)cncc2s1 -US20090042841A1,6,CC(C)(C)OC(=O)N1CCC(=CC#Cc2cc(F)cc(F)c2)CC1>>Fc1cc(F)cc(C#CC=C2CCNCC2)c1 -US08101628B2,3,O=C1NCCN1CCNc1ncc(Cl)c(-c2cc3cccc(Br)c3s2)n1.OB(O)c1cc(F)ncc1Cl>>O=C1NCCN1CCNc1ncc(Cl)c(-c2cc3cccc(-c4cc(F)ncc4Cl)c3s2)n1 -US04271317,7,O=CC=Cc1ccccc1>>OCC=Cc1ccccc1 -US06670373B1,6,COC(=O)c1c(-c2c(F)cccc2Cl)noc1-c1ccccc1>>O=C(O)c1c(-c2c(F)cccc2Cl)noc1-c1ccccc1 -US07414060B2,2,CCOC(=O)c1nc(C)ccc1Nc1cncnc1.Cc1csc(N)n1>>Cc1csc(NC(=O)c2nc(C)ccc2Nc2cncnc2)n1 -US06498172B1,2,COC(=O)CCc1cccc(CNCc2ccc(-c3cccnc3)cc2)c1.O=S(=O)(Cl)c1ccccn1>>COC(=O)CCc1cccc(CN(Cc2ccc(-c3cccnc3)cc2)S(=O)(=O)c2ccccn2)c1 -US08097733B2,1,Cn1nccc1O.NC(=O)C1(c2cccc(Sc3cnc(Cl)c(Cl)c3)c2)CCOCC1>>Cn1nccc1Oc1ncc(Sc2cccc(C3(C(N)=O)CCOCC3)c2)cc1Cl -US20080312234A1,2,C#Cc1cc(CN)cc(F)c1NS(C)(=O)=O.COc1nc(C(C)(C)C)ccc1C=CC(=O)O>>C#Cc1cc(CNC(=O)C=Cc2ccc(C(C)(C)C)nc2OC)cc(F)c1NS(C)(=O)=O -US04760074,1,CCOC(=O)NCCCl.c1ccc2c(c1)nc(NC1CCNCC1)n2Cc1cscn1>>CCOC(=O)NCCN1CCC(Nc2nc3ccccc3n2Cc2cscn2)CC1 -US08158622B2,2,C1CC2(CCN1)OCCO2.O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)O)c1cc2cc(Cl)ncc2[nH]1>>O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC2(CC1)OCCO2)c1cc2cc(Cl)ncc2[nH]1 -US20120142665A1,2,C1COCCN1.Cn1ncc(C(=O)O)c1C(=O)Nc1ccn2nc(N3CCCC3)nc2c1>>Cn1ncc(C(=O)N2CCOCC2)c1C(=O)Nc1ccn2nc(N3CCCC3)nc2c1 -US07691843B2,1,CI.Oc1ccccc1OC(F)(F)F>>COc1ccccc1OC(F)(F)F -US05998665,1,CCNc1nc(Cl)cc(NS(=O)(=O)c2ccc(N)cc2)n1.CN>>CCNc1nc(NC)cc(NS(=O)(=O)c2ccc(N)cc2)n1 -US20150257385A1,6,CC(C)(C)OC(=O)NCCc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1>>NCCc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1 -US20110118236A1,2,CN1CCn2nc(C(N)=O)c(N)c2C1=O.O=C(O)Cn1nc(C(F)(F)F)c2c1CCCC2>>CN1CCn2nc(C(N)=O)c(NC(=O)Cn3nc(C(F)(F)F)c4c3CCCC4)c2C1=O -US04886835,1,CCCCS.CCOC(=O)CBr>>CCCCSCC(=O)OCC -US20060194969A1,1,CI.Cc1nc2c(OCc3ccccc3)cc(CO)cc2n1C>>COCc1cc(OCc2ccccc2)c2nc(C)n(C)c2c1 -US20120122846A1,7,C[Si](C)(C)CCOCn1ncc2ccc([N+](=O)[O-])cc21>>C[Si](C)(C)CCOCn1ncc2ccc(N)cc21 -US05872115,1,NCCBr.Sc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>NCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 -US04220647,2,COc1ccc(CCNC(=O)CNc2ccc(C)cc2)cc1OC.O=C(Cl)OCc1ccccc1>>COc1ccc(CCNC(=O)CN(C(=O)OCc2ccccc2)c2ccc(C)cc2)cc1OC -US20070219178A1,7,CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc(C(=O)O)c1C#N>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc(CO)c1C#N -US07342007B2,2,C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O.N[C@@H]1CC=C[C@@H](c2ccccc2)N(C2CCCC2)C1=O>>C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H]1CC=C[C@@H](c2ccccc2)N(C2CCCC2)C1=O -US20150152047A1,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.CCOC(=O)c1cc(Cl)c(C=O)c(C(F)(F)F)c1>>CCOC(=O)c1cc(Cl)c(CN2CC[C@@H](NC(=O)OC(C)(C)C)C2)c(C(F)(F)F)c1 -US20060069110A1,1,CN(c1ccnc(F)n1)c1ccnc(-c2ccccc2)n1.N[C@H]1CC[C@H](N)CC1>>CN(c1ccnc(NC2CCC(N)CC2)n1)c1ccnc(-c2ccccc2)n1 -US07276516B2,2,CNC.O=C(O)c1ccc(CNC(=O)c2ccc(S(=O)(=O)n3cc(-c4ccccc4)c4ccccc43)cc2)cc1>>CN(C)C(=O)c1ccc(CNC(=O)c2ccc(S(=O)(=O)n3cc(-c4ccccc4)c4ccccc43)cc2)cc1 -US08288541B2,6,Cc1ccc(C)c(N2CCN(C(=O)C3CN(S(=O)(=O)c4ccc(Cl)cc4)CCN3C(=O)OC(C)(C)C)CC2)c1>>Cc1ccc(C)c(N2CCN(C(=O)C3CN(S(=O)(=O)c4ccc(Cl)cc4)CCN3)CC2)c1 -US20110152287A1,6,CC(C)(C)OC(=O)N[C@@H](Cc1cccs1)C(=O)N1CCN(c2nc3ccc(CNC4CCCC4)cc3s2)CC1>>N[C@@H](Cc1cccs1)C(=O)N1CCN(c2nc3ccc(CNC4CCCC4)cc3s2)CC1 -US20030228652A1,1,ClCc1ccccc1.OCCOCCOCCOCCOCCOCCO>>OCCOCCOCCOCCOCCOCCOCc1ccccc1 -US20090149514A1,1,CN1CCC(=O)CC1.NN>>CN1CCC(=NN)CC1 -US07732466B2,2,CC(NC(=O)c1ccc(Cl)s1)C(=O)O.Nc1ccc(C(=O)N2CCCC2)c(Cl)c1>>CC(NC(=O)c1ccc(Cl)s1)C(=O)Nc1ccc(C(=O)N2CCCC2)c(Cl)c1 -US07786163B2,2,COC(=O)C1CSC(CC(NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)N1>>COC(=O)C1CSC2CC(NC(=O)OC(C)(C)C)C(=O)N21 -US06387911B1,1,CC[S-].N#Cc1ncccc1Br>>CCSc1cccnc1C#N -US08022062B2,3,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCc3ccc(Br)cn3)c2CC1.[Zn+]C1CCCCC1>>CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCc3ccc(C4CCCCC4)cn3)c2CC1 -US20120245176A1,2,Cc1onc(-c2ccccc2Cl)c1C(=O)O.O=[N+]([O-])c1ccc(N2CCNCC2)c(Cl)c1>>Cc1onc(-c2ccccc2Cl)c1C(=O)N1CCN(c2ccc([N+](=O)[O-])cc2Cl)CC1 -US04751223,7,N#CC1Nc2ccccc2N2CCc3cccc1c32>>NCC1Nc2ccccc2N2CCc3cccc1c32 -US20130296312A1,7,O=[N+]([O-])c1cnn(CCN2CCCC2)c1>>Nc1cnn(CCN2CCCC2)c1 -US05428065,1,BrCCCCCCCCc1ccccc1.Cc1cc(C=O)c(O)c(C=O)c1>>Cc1cc(C=O)c(OCCCCCCCCc2ccccc2)c(C=O)c1 -US07368471B2,6,CCOC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3cccc(OC(F)(F)F)c3)cc12>>O=C(O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3cccc(OC(F)(F)F)c3)cc12 -US08569522B2,6,COC(=O)C1CCOc2cc(Oc3ccc(C(=O)Nc4ccc5c(c4)CN(C(=O)OC(C)(C)C)CC5)cc3)c(C#N)cc21>>CC(C)(C)OC(=O)N1CCc2ccc(NC(=O)c3ccc(Oc4cc5c(cc4C#N)C(C(=O)O)CCO5)cc3)cc2C1 -US20050143422A1,1,CI.Cc1c(C(=O)OC(C)(C)C)oc2ccc(Br)c(O)c12>>COc1c(Br)ccc2oc(C(=O)OC(C)(C)C)c(C)c12 -US20110086853A1,2,C1COCCN1.CC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CCOCC3)ccc2n1CC1CCOCC1 -US08222251B2,3,C[C@H]1CN(c2nnc(Cl)c3ccncc23)CCN1.OB(O)c1ccc(C(F)(F)F)cc1>>C[C@H]1CN(c2nnc(-c3ccc(C(F)(F)F)cc3)c3ccncc23)CCN1 -US04210754,2,NCCN1CCOCC1.O=C(Cl)c1ccc(Cl)cc1>>O=C(NCCN1CCOCC1)c1ccc(Cl)cc1 -US08519135B2,3,CN(C)C=O.COCN(c1cc(C)cnc1Br)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>COCN(c1cc(C)cnc1C=O)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20080255143A1,2,CCNc1c(Br)cnc(Cl)c1N.N#CCC(=O)O>>CCNc1c(Br)cnc(Cl)c1NC(=O)CC#N -US07528136B2,2,CCOC(=O)N1CCNCC1.O=C(O)C1CC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1Cc1ccccc1>>CCOC(=O)N1CCN(C(=O)[C@@H]2C[C@H](NCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CN2Cc2ccccc2)CC1 -US20120121540A1,2,CS(=O)(=O)Cl.NC1CN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)CC1c1ccccc1>>CS(=O)(=O)NC1CN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)CC1c1ccccc1 -US08063249B1,6,CC/C(=C(/c1ccc(OCCNCCCCCCSCCCC(F)(F)C(F)(F)F)cc1)c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1)c1ccccc1>>CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCNCCCCCCSCCCC(F)(F)C(F)(F)F)cc1)c1ccccc1 -US20120184542A1,6,COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(c4ccccc4)C(F)(F)CNC(=O)OC(C)(C)C)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(c4ccccc4)C(F)(F)CN)ccc3Cl)c(=O)[nH]c2n1 -US07304065B2,1,CI.N#Cc1ccc2c(c1)CCC(NC(=O)c1ccc(-c3ccc(F)cc3)cc1)C2>>CN(C(=O)c1ccc(-c2ccc(F)cc2)cc1)C1CCc2cc(C#N)ccc2C1 -US20140323478A1,3,CCn1c(=O)c(Br)cc2cnc(NCCC3CCN(C)CC3)nc21.O=S(=O)(c1ccc(B(O)O)cc1)C1CC1>>CCn1c(=O)c(-c2ccc(S(=O)(=O)C3CC3)cc2)cc2cnc(NCCC3CCN(C)CC3)nc21 -US20100016321A1,1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.Nc1ccc(N2CCOCC2)cc1>>CC(C)(C)N1C(=O)C(Nc2ccc(N3CCOCC3)cc2)=C(c2ccccc2)S1(=O)=O -US20080280900A1,1,CC=O.NCC(F)(F)F>>CCNCC(F)(F)F -US07544835B2,2,CCOc1ccc(CC(C(=O)OC)C(=O)OC)cc1CO.COc1cccc(N=C=O)c1>>CCOc1ccc(CC(C(=O)OC)C(=O)OC)cc1COC(=O)Nc1cccc(OC)c1 -US20090036434A1,1,CC(C)OC(=O)N1CCC(Oc2ccnc(Cl)c2)CC1.CS(=O)(=O)c1ccc(N)c(F)c1>>CC(C)OC(=O)N1CCC(Oc2ccnc(Nc3ccc(S(C)(=O)=O)cc3F)c2)CC1 -US20090324581A1,1,CC(C)(C)OC(=O)N1CCc2cc(O)ccc21.CS(=O)(=O)OCCCc1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCc2cc(OCCCc3ccc(F)cc3F)ccc21 -US07910619B2,9,CCOc1ccc(C(O)c2ccc(OCc3ccccc3)c(Br)c2)cc1>>CCOc1ccc(Cc2ccc(OCc3ccccc3)c(Br)c2)cc1 -US20130289033A1,3,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1.OB(O)c1ccc(Cl)cc1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(-c2ccc(Cl)cc2)c1 -US20080132525A1,1,CC=O.CN(CC[C@H](NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21>>CCNc1ncnc2c1ncn2[C@@H]1O[C@H](CN(C)CC[C@H](NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)[C@H]2OC(C)(C)O[C@H]21 -US20060183730A1,6,C=CCOC(=O)Nc1cc(C(C)=O)ccc1CC(=O)OCC>>C=CCOC(=O)Nc1cc(C(C)=O)ccc1CC(=O)O -US07145015B2,8,O=C(OO)c1cccc(Cl)c1.Oc1ccc2c(c1)CCCC(c1ccccc1)=C2c1ccc(OCCCCCSCCCC(F)(F)F)cc1>>O=S(CCCCCOc1ccc(C2=C(c3ccccc3)CCCc3cc(O)ccc32)cc1)CCCC(F)(F)F -US08017780B1,1,Clc1ccccc1CCBr.Nc1nccc2[nH]c(Sc3cc4c(cc3Br)OCO4)nc12>>Nc1nccc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCc1ccccc1Cl -US08592463B2,1,CI.Fc1ccc(Br)cc1-c1nc2ccccc2[nH]1>>Cn1c(-c2cc(Br)ccc2F)nc2ccccc21 -US20090012055A1,1,CC(C)(C)OC(=O)N1CCC(c2ccc(O)cc2)C(O)C1.Fc1ccc(OCCCBr)cc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCOc3ccc(F)cc3)cc2)C(O)C1 -US07547779B2,2,CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(N)c3)cc21.O=C(O)c1ccc(OCCN2CCOCC2)cc1>>CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc21 -US20140364413A1,3,Brc1ccc(Br)nc1.CCOC(=O)CCI>>CCOC(=O)CCc1ccc(Br)cn1 -US20040235823A1,5,C1=CCNC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=CC1 -US20040121965A1,6,CCCC[C@@H](/C=C(\C)C(=O)OCC)N(C)C(=O)OC(C)(C)C>>CCCC[C@@H](/C=C(\C)C(=O)OCC)NC -US04435406,6,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])OC(C)O2>>CC1Oc2cc(N)c([N+](=O)[O-])cc2O1 -US08461134B2,6,O=C(Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CCF)c1)C(F)(F)F>>Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CCF)c1 -US05438074,1,CO.COC=Cc1ccc2oc(Cc3nc(-c4ccccc4)oc3C)cc2c1>>COC(Cc1ccc2oc(Cc3nc(-c4ccccc4)oc3C)cc2c1)OC -US05965745,6,COC(=O)c1ccc(Cc2cn(C(F)F)c3ccc(NC(=O)OC4CCCC4)cc23)c(OC)c1>>COc1cc(C(=O)O)ccc1Cc1cn(C(F)F)c2ccc(NC(=O)OC3CCCC3)cc12 -US04864028,3,COC(=O)c1cc(F)ccc1Br.Cc1cc(B(O)O)ccc1F>>COC(=O)c1cc(F)ccc1-c1ccc(F)c(C)c1 -US20110294780A1,1,BrCc1ccccn1.O=C1NC(=O)/C(=C/c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)S1>>O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1Cc1ccccn1 -US04168385,1,COC(=O)C(Br)c1ccc(Oc2ccc(Cl)cc2)cc1.Oc1cccc2ccccc12>>COC(=O)C(Oc1cccc2ccccc12)c1ccc(Oc2ccc(Cl)cc2)cc1 -US05254685,6,COC(=O)c1cn2c3c(c(F)c(F)cc3c1=O)CC(C)N2C>>CC1Cc2c(F)c(F)cc3c(=O)c(C(=O)O)cn(c23)N1C -US20130274469A1,2,COC(=O)c1ccc(NCc2c(-c3cccc(F)c3)noc2C)nc1.NCC(F)(F)F>>Cc1onc(-c2cccc(F)c2)c1CNc1ccc(C(=O)NCC(F)(F)F)cn1 -US20100144755A1,3,CC1(C)OB(c2ccc(C(=O)O)cc2)OC1(C)C.CCN(CC)CCCNc1nc(Cl)c2ccc(=O)n(-c3c(F)cccc3F)c2n1>>CCN(CC)CCCNc1nc(-c2ccc(C(=O)O)cc2)c2ccc(=O)n(-c3c(F)cccc3F)c2n1 -US20140206673A1,2,CC(C)(C)OC(=O)N1CCc2c(C#N)c(N3CCN[C@H](C4CC4)C3)nc(C3CC3)c2C1.O=C(Cl)C1CC1>>CC(C)(C)OC(=O)N1CCc2c(C#N)c(N3CCN(C(=O)C4CC4)[C@H](C4CC4)C3)nc(C3CC3)c2C1 -US06503914B1,1,Cc1csc2c(NN)ncnc12.O=Cc1cccnc1>>Cc1csc2c(NN=Cc3cccnc3)ncnc12 -US20130184313A1,1,CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(Br)c1.c1ccc(CCCOC[C@@H]2CCNC2)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(N2CC[C@@H](COCCCc3ccccc3)C2)c1 -US06034055,2,CCCCCCCCCCCCN(C(=O)CCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CN.O=C(O)CNC(=O)OCc1ccccc1>>CCCCCCCCCCCCN(C(=O)CCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CNC(=O)CNC(=O)OCc1ccccc1 -US20120015943A1,7,COC(=O)c1ccc2c(c1)C(=O)CCC2>>COC(=O)c1ccc2c(c1)C(O)CCC2 -US20150152096A1,1,CCOC(=O)C1=C(CBr)NC(c2nc(CC(=O)NC(C)C)cs2)=NC1c1ccc(F)cc1Br.O=C(O)C1COCCN1>>CCOC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2nc(CC(=O)NC(C)C)cs2)=NC1c1ccc(F)cc1Br -US20070004730A1,3,C#Cc1ccc(OC(F)F)cc1.Ic1cccnc1>>FC(F)Oc1ccc(C#Cc2cccnc2)cc1 -US20100152230A1,1,CC(C)(O)CN.CCCCCc1cc(Cl)c([N+](=O)[O-])c(Cl)n1>>CCCCCc1cc(NCC(C)(C)O)c([N+](=O)[O-])c(Cl)n1 -US06384051B1,7,CN(C)Cc1cc([N+](=O)[O-])cc2c(Nc3cccc(Br)c3)c(C#N)cnc12>>CN(C)Cc1cc(N)cc2c(Nc3cccc(Br)c3)c(C#N)cnc12 -US20140275179A1,1,C=C(C)c1snc(-c2ccc(CC)cc2)c1CCl.CCOC(=O)CCc1ccc(O)c(C)c1C>>C=C(C)c1snc(-c2ccc(CC)cc2)c1COc1ccc(CCC(=O)OCC)c(C)c1C -US20030073691A1,1,CCI.O=C1c2cnccc2-c2c1c(Cl)nc1cc(O)ccc21>>CCOc1ccc2c3c(c(Cl)nc2c1)C(=O)c1cnccc1-3 -US20100168103A1,6,CC1CN(C(=O)C2CCN(Cc3ccccc3)CC2)CC(C)N1>>CC1CN(C(=O)C2CCNCC2)CC(C)N1 -US05929097,3,CCCC[Sn](CCCC)(CCCC)c1cccnc1.COC(=O)c1cc(Br)cc(C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1>>COC(=O)c1cc(-c2cccnc2)cc(C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 -US07514567B2,3,CCCC[Sn](CCCC)(CCCC)c1ccncc1.O=C1O[C@]2(CN3CCC2CC3)CN1c1cc(Br)co1>>O=C1O[C@]2(CN3CCC2CC3)CN1c1cc(-c2ccncc2)co1 -US04269788,1,CC(=O)CC1(c2ccccc2)C=CCC=C1.CNC>>CC(CC1(c2ccccc2)C=CCC=C1)N(C)C -US20090124671A1,3,C=C(B1OC(C)CC(C)(C)O1)C(F)(F)F.CC(C)(C)OC(=O)Nc1ccc(Br)cc1>>C=C(c1ccc(NC(=O)OC(C)(C)C)cc1)C(F)(F)F -US20050009845A1,3,C#CCNC(C)=O.Fc1cccc(COc2ccc(Nc3ncnc4sc(Br)cc34)cc2Cl)c1>>CC(=O)NCC#Cc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2s1 -US20080221110A1,1,NC1CCN(CC2(O)Cn3c(=O)ccc4ccc(F)c2c43)CC1.O=Cc1cc2c(nn1)OCCC2>>O=c1ccc2ccc(F)c3c2n1CC3(O)CN1CCC(NCc2cc3c(nn2)OCCC3)CC1 -US20120088755A1,7,O=C(Nc1c(Cl)cc(O)cc1[N+](=O)[O-])C1CCOCC1>>Nc1cc(O)cc(Cl)c1NC(=O)C1CCOCC1 -US08765730B2,9,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(OCCCC(=O)O)c(F)c1.NO>>Cc1cc(Cl)ccc1C(C/C(=N\O)c1ccc(=O)n(C)c1)c1ccc(OCCCC(=O)O)c(F)c1 -US20110183973A1,2,CC(=O)OC(C)=O.O=C(OCc1ccccc1)C1CNCCO1>>CC(=O)N1CCOC(C(=O)OCc2ccccc2)C1 -US03941811,8,C[C@@]12CCC[C@H]1[C@@H]1CC[C@@H]3C[C@H](O)CC[C@]3(C)[C@H]1CC2>>C[C@@]12CCC[C@H]1[C@@H]1CC[C@@H]3CC(=O)CC[C@]3(C)[C@H]1CC2 -US20100168062A1,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.ClCCCN1CCOCC1>>CC1(C)OB(c2cnn(CCCN3CCOCC3)c2)OC1(C)C -US20050288367A1,1,CNC(=O)C(C)(C)Oc1ccc(O)cc1.Fc1cccc(CBr)c1>>CNC(=O)C(C)(C)Oc1ccc(OCc2cccc(F)c2)cc1 -US20040077859A1,1,CCO.Nc1cc(Cl)nc(N)n1>>CCOc1cc(N)nc(N)n1 -US20140121200A1,2,CC1(C)OB(c2cnn(C3CCNCC3)c2)OC1(C)C.CS(=O)(=O)Cl>>CC1(C)OB(c2cnn(C3CCN(S(C)(=O)=O)CC3)c2)OC1(C)C -US06093732,7,CC(=O)/C=C/c1cc(F)c2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2c1>>CC(=O)CCc1cc(F)c2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2c1 -US20070088044A1,1,CN(C)[C@@H]1CCNC1.O=c1[nH]cnc2cc(F)cc(O)c12>>CN(C)[C@@H]1CCN(c2cc(O)c3c(=O)[nH]cnc3c2)C1 -US07560558B2,8,Cc1cc(C(O)c2nc(C)c(C)s2)oc1C>>Cc1cc(C(=O)c2nc(C)c(C)s2)oc1C -US05273999,1,BrCCCCCBr.O=Cc1cc(Cl)ccc1O>>O=Cc1cc(Cl)ccc1OCCCCCBr -US20150191461A1,1,Cc1cc(N)cc(Br)c1.Fc1cnc(Cl)nc1C(F)F>>Cc1cc(Br)cc(Nc2ncc(F)c(C(F)F)n2)c1 -US07713994B2,2,CNC.O=C(O)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>CN(C)C(=O)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1 -US05641430,1,CCCCC[Si]1(c2ccccc2)CCC(CBr)CC1.Oc1ccc(OC(F)(F)F)cc1>>CCCCC[Si]1(c2ccccc2)CCC(COc2ccc(OC(F)(F)F)cc2)CC1 -US20110301128A1,3,CCOC(=O)c1[nH]c(C)c(Br)c1C.OB(O)c1ccccc1C(F)(F)F>>CCOC(=O)c1[nH]c(C)c(-c2ccccc2C(F)(F)F)c1C -US20150031686A1,1,COc1cc(N)ccc1-c1cnco1.O=Cc1cc2ccccc2s1>>COc1cc(NCc2cc3ccccc3s2)ccc1-c1cnco1 -US05952368,2,CN=C=O.Cc1cc(Cc2ccc(N)cn2)n(C)c1C(=O)c1ccc(Cl)cc1>>CNC(=O)Nc1ccc(Cc2cc(C)c(C(=O)c3ccc(Cl)cc3)n2C)nc1 -US20030130261A1,6,COc1cccc2c1CC1CNCC2C1>>Oc1cccc2c1CC1CNCC2C1 -US07495007B2,9,O=C(O)c1cc(Cl)ccc1I>>O=Cc1cc(Cl)ccc1I -US20040171643A1,1,BrCc1ccccc1Br.OC1CCCCC1>>Brc1ccccc1COC1CCCCC1 -US20060247210A1,2,Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)Cl)cc2s1.NCc1ccc(Cl)cc1>>Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)NCc3ccc(Cl)cc3)cc2s1 -US07491819B1,1,CC1(C)OCCn2c1nc(C(=O)NCc1ccc(F)cc1N1C(=O)CC[C@@H]1COS(C)(=O)=O)c(OCc1ccccc1)c2=O.[N-]=[N+]=[N-]>>CC1(C)OCCn2c1nc(C(=O)NCc1ccc(F)cc1N1C(=O)CC[C@@H]1CN=[N+]=[N-])c(OCc1ccccc1)c2=O -US20120277237A1,3,Brc1ccccn1.C#CCCc1nc2c(F)cccc2o1>>Fc1cccc2oc(CCC#Cc3ccccn3)nc12 -US05846982,7,O=C(CN1CC=C(c2c[nH]c3cc(Cl)ccc23)CC1)Nc1ccccn1>>Clc1ccc2c(C3=CCN(CCNc4ccccn4)CC3)c[nH]c2c1 -US20050222159A1,3,C#Cc1ccccc1.CC(C)n1nc(-c2nc(Br)c(N)nc2-c2ccccc2)ccc1=O>>CC(C)n1nc(-c2nc(C#Cc3ccccc3)c(N)nc2-c2ccccc2)ccc1=O -US20140343065A1,3,CB1OB(C)OB(C)O1.CC(=O)Cc1c(Cl)ccnc1C(=O)NC(C)(C)C>>CC(=O)Cc1c(C)ccnc1C(=O)NC(C)(C)C -US08664220B2,3,CCOC(=O)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cc1noc(-c2ccc(Br)cc2)c1C(O)c1cn(Cc2ccc(Cl)c(Cl)c2)nn1>>CCOC(=O)Cc1ccc(-c2ccc(-c3onc(C)c3C(O)c3cn(Cc4ccc(Cl)c(Cl)c4)nn3)cc2)cc1 -US05455273,2,CNCc1cc(CCCO)ccc1[C@@H]1CC[C@@H](NC)CC1.Cc1cc(C(=O)Cl)ccc1Cl>>CNCc1cc(CCCO)ccc1[C@@H]1CC[C@@H](N(C)C(=O)c2ccc(Cl)c(C)c2)CC1 -US20100041722A1,7,COC(=O)c1cncn1C1Cc2ccccc2C1>>OCc1cncn1C1Cc2ccccc2C1 -US07772183B2,2,CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(O)CN2C1=O.Cc1cc(C(=O)Cl)no1>>Cc1cc(C(=O)OC2CC3C(=O)NC4(C(=O)NS(=O)(=O)C5CC5)CC4C=CCCCCCC(NC(=O)OC(C)(C)C)C(=O)N3C2)no1 -US20110130380A1,2,CC(C)(C)OC(=O)N1CCC[C@H](C(=O)O)C1.Nc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1>>CC(C)(C)OC(=O)N1CCC[C@H](C(=O)Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1 -US20140187588A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]1OC(=O)[C@@H](NC(=O)OC(C)(C)C)CCC[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>C[C@@H]1OC(=O)[C@@H](N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)CCC[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US20140171430A1,2,O=C(O)c1ccccc1Br.c1ccc(-c2ccnc(N3CC4CNCC4C3)n2)cc1>>O=C(c1ccccc1Br)N1CC2CN(c3nccc(-c4ccccc4)n3)CC2C1 -US20120316147A1,2,Cc1nc(C(C)(C)N)no1.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>Cc1nc(C(C)(C)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)no1 -US20120108585A1,3,ClCc1ccnc2sc(Cl)nc12.OB(O)c1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(-c2nc3c(CCl)ccnc3s2)c1 -US20030144263A1,1,O=C1CCN(c2ccc(N3C[C@H](COc4ccon4)OC3=O)cc2F)CC1.[NH4+]>>NC1CCN(c2ccc(N3C[C@H](COc4ccon4)OC3=O)cc2F)CC1 -US20080300243A1,3,CN(C)C=O.COC(=O)c1ccc(Br)cc1OC>>COC(=O)c1ccc(C=O)cc1OC -US20060178359A1,6,CCCCOCCOc1ccc(-c2cc3c4c(c2)CCCN4CCC(C(=O)OCC)=C3)cc1>>CCCCOCCOc1ccc(-c2cc3c4c(c2)CCCN4CCC(C(=O)O)=C3)cc1 -US20050282862A1,2,Nc1ccccc1C(=O)Nc1ccc(Cl)cn1.O=C(Cl)c1ccc(-c2ccccc2)cc1>>O=C(Nc1ccccc1C(=O)Nc1ccc(Cl)cn1)c1ccc(-c2ccccc2)cc1 -US07893267B2,7,Nc1cc(OCc2ccccc2)cc(C(=O)OCc2ccccc2)c1[N+](=O)[O-]>>Nc1cc(OCc2ccccc2)cc(C(=O)OCc2ccccc2)c1N -US20100130737A1,2,COC(=O)[C@@H](N)Cc1ccc(OCc2ccc(Cl)cc2)cc1.O=C(O)c1cn2ccc(-c3ccc(Cl)cc3)cc2n1>>COC(=O)[C@H](Cc1ccc(OCc2ccc(Cl)cc2)cc1)NC(=O)c1cn2ccc(-c3ccc(Cl)cc3)cc2n1 -US06046235,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(CSC[C@H](N)C(=O)O)cc1>>Cc1ccc(CSC[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1 -US04299829,6,CCOC(=O)C(=NOC)c1csc(N)n1>>CON=C(C(=O)O)c1csc(N)n1 -US05324747,6,CCCCCCCCCCCCCCCCCCOc1cc(NC(=O)OCc2ccccc2)cc(OCCCP(=O)(OCC)OCC)c1>>CCCCCCCCCCCCCCCCCCOc1cc(N)cc(OCCCP(=O)(OCC)OCC)c1 -US07666879B2,7,Nc1cc(C(=O)N2CCOCC2)cc(C(F)(F)F)c1>>Nc1cc(CN2CCOCC2)cc(C(F)(F)F)c1 -US07863293B2,1,CC(C)(c1ccccc1)c1cccnc1C=O.Cc1cc(Cl)cnc1CNC1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc(Cl)cnc1CN(Cc1ncccc1C(C)(C)c1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1 -US20080051416A1,2,Cc1c(F)cc(C(=O)O)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O.NCc1ccc(F)cc1>>Cc1c(F)cc(C(=O)NCc2ccc(F)cc2)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O -US20080027050A1,6,CCOC(=O)c1ccc(COCc2csc3nc(C(=O)NCc4cccc(S(C)(=O)=O)c4)[nH]c(=O)c23)cc1>>CS(=O)(=O)c1cccc(CNC(=O)c2nc3scc(COCc4ccc(C(=O)O)cc4)c3c(=O)[nH]2)c1 -US20100273793A1,2,Nc1nc2ccc(OCc3c(Cl)cccc3Cl)cc2s1.O=C(O)C1CC1>>O=C(Nc1nc2ccc(OCc3c(Cl)cccc3Cl)cc2s1)C1CC1 -US20110152318A1,1,CC(NC(=O)c1coc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1.CC1(C)Cc2cccc(O)c2O1>>CC(NC(=O)c1coc(Oc2cccc3c2OC(C)(C)C3)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1 -US04027023,6,CCOC(=O)c1cc2cc(CC)ccc2nn1>>CCc1ccc2nnc(C(=O)O)cc2c1 -US20100016401A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1NCC2CC21>>CC(C)(C)OC(=O)N1CC2CC2C1C(=O)O -US20120329784A1,1,C=O.O=[N+]([O-])c1ccc2c(c1)CNCC2>>CN1CCc2ccc([N+](=O)[O-])cc2C1 -US07507740B2,1,O=[N+]([O-])c1ccc(F)c(Cl)c1.Oc1ccc(CCCn2ccnc2)cc1>>O=[N+]([O-])c1ccc(Oc2ccc(CCCn3ccnc3)cc2)c(Cl)c1 -US06518423B1,2,CS(=O)(=O)Cl.NC1CCN(Cc2ccccc2)CC1>>CS(=O)(=O)NC1CCN(Cc2ccccc2)CC1 -US20150038528A1,9,COC(=O)c1nc(I)c2cc(Oc3ccccc3OC)ccc2c1O.N#C[Cu]>>COC(=O)c1nc(C#N)c2cc(Oc3ccccc3OC)ccc2c1O -US20150210685A1,2,Brc1ccc(N2CCNCC2)cc1.O=S(=O)(Cl)C1CC1>>O=S(=O)(C1CC1)N1CCN(c2ccc(Br)cc2)CC1 -US04617407,6,CCCc1cc(CC(=O)OC)ccc1OC1COc2ccc(C(C)=O)c(O)c2C1>>CCCc1cc(CC(=O)O)ccc1OC1COc2ccc(C(C)=O)c(O)c2C1 -US20100184802A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1Cn1ccc2c(NC(=O)CC3(O)CCCCCC3)cccc2c1=O>>O=C(CC1(O)CCCCCC1)Nc1cccc2c(=O)n(C[C@H]3CCCN3)ccc12 -US20090030015A1,6,COC(=O)c1ccc(-c2ccccc2NC(=O)c2cccc(-c3ccc(OC)cc3OC)c2)s1>>COc1ccc(-c2cccc(C(=O)Nc3ccccc3-c3ccc(C(=O)O)s3)c2)c(OC)c1 -US06908930B2,1,C#Cc1cccc(N)c1.Cc1cc(C(=O)NCCN2CCOCC2)[nH]c1C=C1C(=O)Nc2ncnc(Cl)c21>>C#Cc1cccc(Nc2ncnc3c2C(=Cc2[nH]c(C(=O)NCCN4CCOCC4)cc2C)C(=O)N3)c1 -US20080275032A1,1,CC(C)(C)CCBr.CCOC(=O)c1c(O)c(-c2cccs2)n[nH]c1=O>>CCOC(=O)c1c(O)c(-c2cccs2)nn(CCC(C)(C)C)c1=O -US04931444,4,CCn1c(=O)ccn(-c2ccc(N)cc2)c1=O.COc1ccc(N(CCCl)CCCl)cc1>>CCn1c(=O)ccn(-c2ccc(N3CCN(c4ccc(OC)cc4)CC3)cc2)c1=O -US05245068,2,CCCCCCCCCCCCO.O=C=NS(=O)(=O)Cl>>CCCCCCCCCCCCOC(=O)NS(=O)(=O)Cl -US20150152096A1,1,CCOC(=O)C1=C(CBr)NC(c2nccs2)=NC1c1ccc(F)cc1Br.OC[C@@H]1CNCCO1>>CCOC(=O)C1=C(CN2CCO[C@H](CO)C2)NC(c2nccs2)=NC1c1ccc(F)cc1Br -US05510510,9,O=C1NC(=O)c2c(O)cccc21>>O=C1NC(=O)c2ccccc21 -US20090181942A1,2,CCOC(=O)CC1CCNCC1.COc1cccc([C@H]2O[C@H](CCC(=O)O)c3ccc(-c4nn[nH]n4)n3-c3ccc(Cl)cc32)c1OC>>CCOC(=O)CC1CCN(C(=O)CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c(-c4nn[nH]n4)ccc32)CC1 -US20060241142A1,1,C=O.COc1c(C#N)cc2ccccc2c1C(=O)NCC1(c2ccc(Cl)c(Cl)c2)CCNCC1>>COc1c(C#N)cc2ccccc2c1C(=O)NCC1(c2ccc(Cl)c(Cl)c2)CCN(C)CC1 -US07091232B2,3,CC1=C(Br)C(O)CC1.CC[Mg+]>>CCC1=C(C)CCC1O -US20100261723A1,2,CC(=O)Cl.Nc1ccc(Br)cc1CO>>CC(=O)Nc1ccc(Br)cc1CO -US20100298343A1,1,CCOC(=O)C(Cc1ccccc1)c1[nH]c2ccc(O)cc2c1SC(C)(C)C.Cc1ccc(CCl)nc1>>CCOC(=O)C(Cc1ccccc1)c1[nH]c2ccc(OCc3ccc(C)cn3)cc2c1SC(C)(C)C -US20150225389A1,2,CCCCCCOC(=O)Cl.CCOC(=O)[C@@H]1[C@@H](Cc2ccnc(N)c2)C(=O)N1C(=O)N[C@H](C)c1ccccc1>>CCCCCCOC(=O)Nc1cc(C[C@H]2C(=O)N(C(=O)N[C@H](C)c3ccccc3)[C@@H]2C(=O)OCC)ccn1 -US05010060,1,CCI.CCc1cn([C@H]2C[C@H](O)[C@@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O>>CCO[C@H]1C[C@H](n2cc(CC)c(=O)[nH]c2=O)O[C@@H]1COC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20100004238A1,1,O=[N+]([O-])c1ccc(F)c(Cl)c1.Oc1cccn2nccc12>>O=[N+]([O-])c1ccc(Oc2cccn3nccc23)c(Cl)c1 -US04044010,1,CCOC(=O)N1CCNCC1.Fc1ccc2c(c1)C(Cl)Cc1ccc(Cl)cc1S2>>CCOC(=O)N1CCN(C2Cc3ccc(Cl)cc3Sc3ccc(F)cc32)CC1 -US20040082625A1,3,Brc1ccncc1.COc1ccc(C=O)cc1B(O)O>>COc1ccc(C=O)cc1-c1ccncc1 -US20120283216A1,2,CC(C)(N)C#N.CCOc1ccc2ccc(OC(CC)C(=O)O)cc2c1>>CCOc1ccc2ccc(OC(CC)C(=O)NC(C)(C)C#N)cc2c1 -US07868205B2,2,CC(C)(C)OC(=O)Nc1nc(-c2ccc([N+](=O)[O-])c(N)c2)cs1.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)Nc2cc(-c3csc(NC(=O)OC(C)(C)C)n3)ccc2[N+](=O)[O-])cc1 -US20100120810A1,2,CC(=O)Cl.COc1cc2cc(-c3ccccc3N)nc(C)c2cc1OC>>COc1cc2cc(-c3ccccc3NC(C)=O)nc(C)c2cc1OC -US08829052B2,2,Cc1cc(S(=O)(=O)Cl)c(C)s1.Nc1ccc(F)c(F)c1Nc1ccc(I)cc1F>>Cc1cc(S(=O)(=O)Nc2ccc(F)c(F)c2Nc2ccc(I)cc2F)c(C)s1 -US09050345B2,9,Clc1nc(Cl)c2c(-c3ccccc3)ccn2n1.N>>Nc1nc(Cl)nn2ccc(-c3ccccc3)c12 -US20110251196A1,2,CC(C)(C)OC(=O)N1CCC[C@@H]1C(N)c1ccc(OCc2ccccc2)cc1.C[C@H](C(=O)O)c1ccccc1>>C[C@H](C(=O)N[C@H](c1ccc(OCc2ccccc2)cc1)[C@H]1CCCN1C(=O)OC(C)(C)C)c1ccccc1 -US08530470B2,6,COC(=O)c1cc(C2CCCN2C(=O)OC(C)(C)C)c2oc(N3CCO[C@H](C)C3)cc(=O)c2c1>>COC(=O)c1cc(C2CCCN2)c2oc(N3CCO[C@H](C)C3)cc(=O)c2c1 -US07714000B2,1,Cc1cc(Br)ccc1C(=O)OC(C)(C)C.NCc1ccccc1>>Cc1cc(NCc2ccccc2)ccc1C(=O)OC(C)(C)C -US06451821B1,6,CC(=O)N[C@@H](CO)Cc1cccc(C(=O)O)c1>>N[C@@H](CO)Cc1cccc(C(=O)O)c1 -US09156827B2,1,CC(C)(C)OC(=O)N1CCNCC1.COc1cc(C(C)=O)c(O)c(C=O)c1OC>>COc1cc(C(C)=O)c(O)c(CN2CCN(C(=O)OC(C)(C)C)CC2)c1OC -US20130225552A1,1,CC(C)(C)OC(=O)NC1CNC1.Clc1ccc2ccccc2n1>>CC(C)(C)OC(=O)NC1CN(c2ccc3ccccc3n2)C1 -US20100311748A1,1,O=Cc1ccc(F)cn1.OCCO>>O=Cc1ccc(OCCO)cn1 -US07435751B2,1,CN.O=[N+]([O-])c1ccc(F)c(F)c1>>CNc1ccc([N+](=O)[O-])cc1F -US20110152316A1,9,CC(C)(C)OC(=O)N(Cc1cc(COS(C)(=O)=O)cc(Cl)c1Cl)C1CC1.[C-]#N>>CC(C)(C)OC(=O)N(Cc1cc(CC#N)cc(Cl)c1Cl)C1CC1 -US20070249670A1,6,CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)OCc1ccccc1>>CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)O -US20120142681A1,1,CC(=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1.CN(N)C(N)=O>>C/C(=N\N(C)C(N)=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 -US08680339B2,8,CCc1cc(Br)ccc1C1C(=O)C=CC1O>>CCc1cc(Br)ccc1C1C(=O)C=CC1=O -US05876984,6,C[C@H]1CC[C@H]2C(C)(C)[C@@H](O)CC[C@]23Oc2c(c(OCc4ccccc4)cc4c2CN(C)C4=O)C[C@]13C>>C[C@H]1CC[C@H]2C(C)(C)[C@@H](O)CC[C@]23Oc2c(c(O)cc4c2CN(C)C4=O)C[C@]13C -US05153214,3,Brc1cccnc1.C=CCC(CCCC#N)CCC(=O)OCC>>CCOC(=O)CCC(CC=Cc1cccnc1)CCCC#N -US06410566B1,2,CC(C)c1ccc(S(=O)(=O)Cl)cc1.NCC(=O)NCC1CCN(Cc2ccc(Cl)cc2)CC1>>CC(C)c1ccc(S(=O)(=O)NCC(=O)NCC2CCN(Cc3ccc(Cl)cc3)CC2)cc1 -US20090227603A1,3,CCCC[Sn](CCCC)(CCCC)c1cscn1.CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(I)cc(S(C)(=O)=O)c2)c1CCC(=O)OCC>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(-c3cscn3)cc(S(C)(=O)=O)c2)c1CCC(=O)OCC -US20140018384A1,2,CNOC.COc1cc2c(cn1)c(=O)c(C(=O)O)cn2C(C)(C)CC(C)(C)C>>COc1cc2c(cn1)c(=O)c(C(=O)N(C)OC)cn2C(C)(C)CC(C)(C)C -US20150252033A1,3,COC(=O)c1ccccc1Br.[Zn+]C1CCC1>>COC(=O)c1ccccc1C1CCC1 -US20040092556A1,6,CC(C)(C)OC(=O)N(Cc1ccccn1)Cc1ccc(C(=O)N[C@@H](CCCNC2CCCc3cccnc32)C(=O)O)cn1>>O=C(N[C@@H](CCCNC1CCCc2cccnc21)C(=O)O)c1ccc(CNCc2ccccn2)nc1 -US06326386B1,6,COC(=O)CCCN(C(=O)c1cc(Cl)cc(OCCN(C(=O)OC(C)(C)C)c2ccncc2)c1)c1ccccc1C(N)=O>>COC(=O)CCCN(C(=O)c1cc(Cl)cc(OCCNc2ccncc2)c1)c1ccccc1C(N)=O -US20150231132A1,2,CCOC(=O)CN1CCN(Cc2c(F)cccc2Cl)CC1.NN>>NNC(=O)CN1CCN(Cc2c(F)cccc2Cl)CC1 -US05786358,2,O=C(Cl)OCc1ccccc1.OC1CCNC1>>O=C(OCc1ccccc1)N1CCC(O)C1 -US05744479,1,CC(C)S(=O)c1cn(Cc2c(F)cccc2F)c2sc(-c3ccc([N+](=O)[O-])cc3)c(CBr)c2c1=O.CNCc1ccccc1>>CC(C)S(=O)c1cn(Cc2c(F)cccc2F)c2sc(-c3ccc([N+](=O)[O-])cc3)c(CN(C)Cc3ccccc3)c2c1=O -US20060229315A1,6,CC(NC(=O)c1c(CN2CCN(C(=O)OC(C)(C)C)CC2=O)c(-c2ccccc2)nc2ccc(F)cc12)C1CCCCC1>>C[C@H](NC(=O)c1c(CN2CCNCC2=O)c(-c2ccccc2)nc2ccc(F)cc12)C1CCCCC1 -US08258134B2,8,CC(C)(O)Cn1ccc(NC(=O)C(CC2CCCC2)n2ncc(Sc3ccccc3)cc2=O)n1.O=C(OO)c1cccc(Cl)c1>>CC(C)(O)Cn1ccc(NC(=O)C(CC2CCCC2)n2ncc(S(=O)c3ccccc3)cc2=O)n1 -US20070167447A1,4,COC(=O)c1cnc(N)c(I)c1.C[Si](C)(C)C#CC1CCCCC1>>COC(=O)c1cnc2[nH]c([Si](C)(C)C)c(C3CCCCC3)c2c1 -US07915297B2,2,Nc1cc(-c2ccco2)on1.O=C(O)C=Cc1ccccn1>>O=C(C=Cc1ccccn1)Nc1cc(-c2ccco2)on1 -US20090247567A1,2,CNC.CNc1ccc(C(=O)O)cc1Cl>>CNc1ccc(C(=O)N(C)C)cc1Cl -US20140087992A1,2,CNOC.Cc1cccc(C(=O)O)c1[N+](=O)[O-]>>CON(C)C(=O)c1cccc(C)c1[N+](=O)[O-] -US05539112,1,CC(C)(C)C(=O)Nc1ccc(-c2cc(=O)c3c(NCCCOS(C)(=O)=O)c(F)cc(F)c3o2)cc1F.CNC>>CN(C)CCCNc1c(F)cc(F)c2oc(-c3ccc(NC(=O)C(C)(C)C)c(F)c3)cc(=O)c12 -US20070249670A1,7,CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2ccccc2)cc1[N+](=O)[O-])C1CCCCC1>>CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2ccccc2)cc1N)C1CCCCC1 -US06762180B1,1,CCI.O=[N+]([O-])c1ccc(-c2ncc[nH]2)cc1>>CCn1ccnc1-c1ccc([N+](=O)[O-])cc1 -US20060069286A1,2,Nc1ccccc1.O=C(N[C@@H](Cc1ccc(Cl)c(Cl)c1)C(=O)O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12>>O=C(N[C@@H](Cc1ccc(Cl)c(Cl)c1)C(=O)Nc1ccccc1)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 -US20090264435A1,1,C1CCC(N2CCNCC2)C1.CS(=O)(=O)c1ccc(-c2ccc(Cl)nn2)cc1>>CS(=O)(=O)c1ccc(-c2ccc(N3CCN(C4CCCC4)CC3)nn2)cc1 -US04046772,1,CO.NC(=O)c1nc2n(n1)-c1ccc(Cl)cc1C(c1ccccc1)=NC2O>>COC1N=C(c2ccccc2)c2cc(Cl)ccc2-n2nc(C(N)=O)nc21 -US04820715,1,CC(C)C(=O)CBr.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1O>>CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)C(C)C -US04672064,1,COc1ccc2c(c1)SC(CCCCl)C(O)CO2.c1ccc(N2CCNCC2)cc1>>COc1ccc2c(c1)S[C@H](CCCN1CCN(c3ccccc3)CC1)[C@H](O)CO2 -US20140364433A1,1,Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.FC(F)(F)c1ccc(Cl)nn1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(C(F)(F)F)nn2)c1 -US08476286B2,1,C#CCOc1ccc(N)c(C(=O)c2ccc(C(C)C)cc2)c1.O=[N+]([O-])c1cccc(CBr)c1>>C#CCOc1ccc(NCc2cccc([N+](=O)[O-])c2)c(C(=O)c2ccc(C(C)C)cc2)c1 -US20030199532A1,6,COC(=O)CC(=O)N1C[C@H](Cc2ccc(Cl)c(Cl)c2)C[C@H]1CCNC(=O)CSc1ncc(-c2ccc(OC)c(OC)c2)cn1>>COc1ccc(-c2cnc(SCC(=O)NCC[C@@H]3C[C@@H](Cc4ccc(Cl)c(Cl)c4)CN3C(=O)CC(=O)O)nc2)cc1OC -US04764205,1,CI.O=c1[nH]nc(-c2ccccc2SCc2ccccc2)o1>>Cn1nc(-c2ccccc2SCc2ccccc2)oc1=O -US20100305066A1,1,CN(C)CCN.Clc1ccc(I)cn1>>CN(C)CCNc1ccc(I)cn1 -US06784167B2,7,CCOC(=O)[C@H]1[C@@H](c2ccc([N+](=O)[O-])cc2)CC(=O)N1C>>CCOC(=O)[C@H]1[C@@H](c2ccc(N)cc2)CC(=O)N1C -US20140213586A1,1,COc1cc(N)cc(OC)c1.Cn1cc(C(=O)C(Br)c2ccccc2)c2ccccc21>>COc1cc(NC(C(=O)c2cn(C)c3ccccc23)c2ccccc2)cc(OC)c1 -US07517884B2,6,O=C1C2CSCC(C(=O)N1c1ccc(OC(F)(F)F)cc1)N2Cc1ccccc1>>O=C1C2CSCC(N2)C(=O)N1c1ccc(OC(F)(F)F)cc1 -US20060004017A1,1,COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1O.OCCN1CCOCC1>>COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1OCCN1CCOCC1 -US04591458,1,BrCc1ccccc1.CC(C)(C)OC(=O)CN1C(=O)[C@@H](N[C@@H](CCC2CCCCC2)C(=O)O)COc2ccccc21>>CC(C)(C)OC(=O)CN1C(=O)[C@@H](N[C@@H](CCC2CCCCC2)C(=O)OCc2ccccc2)COc2ccccc21 -US20100298324A1,2,COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)n1.CS(=O)(=O)c1ccc(CN)cc1>>COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(S(C)(=O)=O)cc4)ccc3c2=O)n1 -US05670504,1,COc1ccc(NN=C(Cl)C(C)=O)cc1.O=[N+]([O-])c1ccc(S)cc1>>COc1ccc(NN=C(Sc2ccc([N+](=O)[O-])cc2)C(C)=O)cc1 -US04695581,4,CCC(=O)c1cc(C)c(OC)c(C)c1.NNc1ccccc1>>COc1c(C)cc(-c2[nH]c3ccccc3c2C)cc1C -US07132456B2,2,CN(C)CCN.O=C(O)c1ccccc1-c1ccc(CSCCOc2ccccc2)cc1>>CN(C)CCNC(=O)c1ccccc1-c1ccc(CSCCOc2ccccc2)cc1 -US20130190290A1,6,Cc1ccc(NC(=O)c2cc(OCCNC(=O)OC(C)(C)C)cc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12>>Cc1ccc(NC(=O)c2cc(OCCN)cc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 -US20080027076A1,1,CC(C)(C)c1cc(NC(=O)Nc2cccc(C#Cc3cncnc3Cl)c2)no1.NCCCCN>>CC(C)(C)c1cc(NC(=O)Nc2cccc(C#Cc3cncnc3NCCCCN)c2)no1 -US06537948B1,7,COC(=O)COc1nc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)ccc1[N+](=O)[O-]>>COC(=O)COc1nc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)ccc1N -US20120172351A1,3,COC(=O)C[C@@H]1COc2cc(NCc3ccc(C)c(Br)c3C)ccc21.Cc1nn(C(F)F)c(C)c1B1OC(C)(C)C(C)(C)O1>>COC(=O)C[C@@H]1COc2cc(NCc3ccc(C)c(-c4c(C)nn(C(F)F)c4C)c3C)ccc21 -US20080132539A1,1,Cc1cc2nc(CC[C@H](NC(=O)OC(C)(C)C)C(=O)OCc3ccccc3)[nH]c2cc1C.Cc1ccc(B(O)O)cc1>>Cc1ccc(-n2c(CC[C@H](NC(=O)OC(C)(C)C)C(=O)OCc3ccccc3)nc3cc(C)c(C)cc32)cc1 -US20050070706A1,10,Cc1sccc1C#N.O=C1CCC(=O)N1Br>>N#Cc1ccsc1CBr -US04234595,7,CC(C)(Cc1c[nH]c2ccc(Br)cc12)[N+](=O)[O-]>>CC(C)(N)Cc1c[nH]c2ccc(Br)cc12 -US04939160,7,COc1ccc2c(c1)C(CC#N)=C2>>COc1ccc2c(c1)C(CCN)=C2 -US20150191431A1,2,Cc1cc(C(=O)O)no1.N[C@@H]1CC[C@@H](Oc2ccnc3c(Br)cccc23)CC1>>Cc1cc(C(=O)N[C@@H]2CC[C@@H](Oc3ccnc4c(Br)cccc34)CC2)no1 -US20120263714A1,6,CC(C)(C)OC(=O)NS(=O)(=O)NCc1cccc(Oc2cc(F)c(F)c(Nc3ccc(I)cc3F)c2C(N)=O)c1>>NC(=O)c1c(Oc2cccc(CNS(N)(=O)=O)c2)cc(F)c(F)c1Nc1ccc(I)cc1F -US20060257987A1,6,CCOC(=O)C(C)(C)Oc1ccc(OCCC(C)Oc2ccc3ccc(-c4ccccc4)cc3c2)cc1>>CC(CCOc1ccc(OC(C)(C)C(=O)O)cc1)Oc1ccc2ccc(-c3ccccc3)cc2c1 -US20140371199A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3ccn4ncc(-c5ccc(C#N)cc5)c4n3)cc2)CC1>>N#Cc1ccc(-c2cnn3ccc(-c4ccc(C(=O)N5CCNCC5)cc4)nc23)cc1 -US20070082907A1,1,CCc1cc(O)ccc1CCC(=O)OC.N#Cc1cccc(Br)c1>>CCc1cc(Oc2cccc(C#N)c2)ccc1CCC(=O)OC -US20070003680A1,3,CC(C)CNC(=O)C(C)(C)c1ccc(Br)cc1.Cc1ccccc1B(O)O>>Cc1ccccc1-c1ccc(C(C)(C)C(=O)NCC(C)C)cc1 -US20070088001A1,3,C[Si](C)(C)CC(NC(=O)c1cccc(I)c1)C(=O)NC1(C#N)CC1.N#Cc1cccc(B(O)O)c1>>C[Si](C)(C)CC(NC(=O)c1cccc(-c2cccc(C#N)c2)c1)C(=O)NC1(C#N)CC1 -US20120071514A1,3,CC[Mg+].Cn1c(=O)oc2ccc(-c3cnccc3C=O)cc21>>CCC(O)c1ccncc1-c1ccc2oc(=O)n(C)c2c1 -US08541448B2,2,CCOP(=O)(CCN)OCC.O=S(=O)(Cl)Cl>>CCOP(=O)(CCNS(=O)(=O)Cl)OCC -US20100130737A1,3,CCOC(=O)C1(NC(=O)Cc2ccc(F)cc2)Cc2ccc(Br)cc2C1.COc1ccc(B(O)O)cc1>>CCOC(=O)C1(NC(=O)Cc2ccc(F)cc2)Cc2ccc(-c3ccc(OC)cc3)cc2C1 -US04349684,6,CCOC(=O)CCCCCCn1c(-c2ccccc2)c(-c2ccccc2)n(CC)c1=O>>CCn1c(-c2ccccc2)c(-c2ccccc2)n(CCCCCCC(=O)O)c1=O -US08003649B2,1,CCOc1ccc(C=O)cn1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>CCOc1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cn1 -US09156834B2,1,Fc1ccc2nc(Cl)sc2c1.O=S(=O)(Nc1ccccc1OCC1CCNC1)c1ccccn1>>O=S(=O)(Nc1ccccc1OCC1CCN(c2nc3ccc(F)cc3s2)C1)c1ccccn1 -US20040006141A1,1,CCCCC(Cc1ccc(OCCCOS(C)(=O)=O)cc1)C(=O)OCC.CN>>CCCCC(Cc1ccc(OCCCNC)cc1)C(=O)OCC -US07410972B2,1,Cc1cc(CO)no1.O=S(=O)(Nc1nc(Cl)cnc1Br)c1ccc(Cl)s1>>Cc1cc(COc2ncc(Cl)nc2NS(=O)(=O)c2ccc(Cl)s2)no1 -USRE045670E1,2,CN(C)S(=O)(=O)Cl.Cc1ccc(NC(=O)Nc2nc(CN)cs2)c(C(=O)C2CCCC2)c1>>Cc1ccc(NC(=O)Nc2nc(CNS(=O)(=O)N(C)C)cs2)c(C(=O)C2CCCC2)c1 -US06936602B1,6,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3Cc2nnn(C)n2)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3Cc2nnn(C)n2)cc1 -US07683168B2,3,C=CCN1C[C@H](C)N([C@@H](c2cccc(O)c2)c2cccc(C(=O)N3CCC(=O)CC3)c2)C[C@H]1C.CCOC(=O)CP(=O)(OCC)OCC>>C=CCN1C[C@H](C)N([C@@H](c2cccc(O)c2)c2cccc(C(=O)N3CCC(=CC(=O)OCC)CC3)c2)C[C@H]1C -US05180833,2,CC(=O)OC(C)=O.CNC(=N[N+](=O)[O-])SC>>CSC(=N[N+](=O)[O-])N(C)C(C)=O -US20080275022A1,2,C1COCCN1.O=C(O)c1cccc(S(=O)(=O)Cl)c1>>O=C(O)c1cccc(S(=O)(=O)N2CCOCC2)c1 -US20100210642A1,3,C#Cc1cnn2c(C(F)F)cc(-c3ccc(Cl)c(C)c3)nc12.CN1CCN(S(=O)(=O)c2ccc(Br)s2)CC1>>Cc1cc(-c2cc(C(F)F)n3ncc(C#Cc4ccc(S(=O)(=O)N5CCN(C)CC5)s4)c3n2)ccc1Cl -US20060287321A1,1,COc1cc([N+](=O)[O-])ccc1Cl.OCCN1CCCC1>>COc1cc([N+](=O)[O-])ccc1OCCN1CCCC1 -US09018229B2,4,CCCOc1cc2ccccc2cc1N.CCOC(=O)C(C(C)=O)c1ccc(OC)cc1>>CCCOc1cc2ccccc2c2c(=O)c(-c3ccc(OC)cc3)c(C)[nH]c12 -US07244713B2,7,C#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@@]2(C)O)c2ncnc(N)c12>>C=Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@@]2(C)O)c2ncnc(N)c12 -US20140023611A1,2,NCCCO.O=C(O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)c1>>O=C(NCCCO)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)c1 -US05811459,6,COC(=O)c1ccc(CCc2ncccc2OCc2ccccc2)cc1>>O=C(O)c1ccc(CCc2ncccc2OCc2ccccc2)cc1 -US05932742,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1.O=C1N[C@@H](c2ccccc2)CN1S(=O)(=O)c1ccc2c(c1)CCN2>>O=C(c1ccc([N+](=O)[O-])cc1)N1CCc2cc(S(=O)(=O)N3C[C@H](c4ccccc4)NC3=O)ccc21 -US20120289505A1,2,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O.O=S(=O)(Cl)c1cccc(Cl)c1>>COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4)cc3)cc2C1=O -US20120184548A1,2,CC(C)(C)OC(=O)NCCN.COc1cc2cc(C(=O)Nc3cc(C(=O)O)ccc3C)c(=O)[nH]c2cc1OC>>COc1cc2cc(C(=O)Nc3cc(C(=O)NCCNC(=O)OC(C)(C)C)ccc3C)c(=O)[nH]c2cc1OC -US08232294B2,2,CN(C)CC(=O)O.COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1>>COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(C[C@H](C)OC(=O)CN(C)C)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 -US05153227,9,O=S(=O)(Cl)c1cccc2ccccc12>>O=S(O)c1cccc2ccccc12 -US05098918,3,COc1ccccc1.O=C(Cl)Cc1ccccc1>>COc1ccc(C(=O)Cc2ccccc2)cc1 -US20050014812A1,7,COC(=O)c1ccccc1COc1ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>COC(=O)c1ccccc1COc1ccc(NC(=O)OC(C)(C)C)c(N)c1 -US06194406B1,1,CCOCCn1c(N2CCCNCC2)nc2ccccc21.COc1cc(CN2CCC(CCOS(C)(=O)=O)(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC>>CCOCCn1c(N2CCCN(CCC3(Cc4ccc(F)cc4)CCN(Cc4cc(OC)c(OC)c(OC)c4)C3=O)CC2)nc2ccccc21 -US20110098241A1,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.OCCC1CCNCC1>>O=C(N1CCC(CCO)CC1)C(F)(F)F -US07060721B1,3,C#Cc1ccccc1.COC(=O)/C=C/c1c(Cl)nc(C)n1Cc1ccc(I)cc1Cl>>COC(=O)/C=C/c1c(Cl)nc(C)n1Cc1ccc(C#Cc2ccccc2)cc1Cl -US20130237525A1,3,CN(C)C=O.COc1ccc2c(c1)OCCO2>>COc1ccc2c(c1C=O)OCCO2 -US04247559,6,CC(=O)Nc1ccc(S(=O)(=O)CI)cc1>>Nc1ccc(S(=O)(=O)CI)cc1 -US20100004280A1,7,CCC(C)(C)Cc1cn(S(=O)(=O)N(C)C)c(C(=O)Cc2ccc(Br)cc2)n1>>CCC(C)(C)Cc1cn(S(=O)(=O)N(C)C)c(C(O)Cc2ccc(Br)cc2)n1 -US20080167322A1,2,CC(C)C(O)CCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC(CCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C(C)C)cc1 -US20130053381A1,1,CC(C)n1nccc1-c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)(F)F.CCCCOC(=O)Cl>>CCCCOC(=O)N(n1c(=O)[nH]c2cc(C(F)(F)F)c(-c3ccnn3C(C)C)cc2c1=O)S(C)(=O)=O -US20070254931A1,6,COC(=O)[C@@H]1CCN(Cc2sc(NC(C)=O)nc2CCc2ccc(N/C(=N/C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc2)C1>>CC(=O)Nc1nc(CCc2ccc(N/C(=N/C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc2)c(CN2CC[C@@H](C(=O)O)C2)s1 -US20130079375A1,2,CNOC.O=C(O)c1cnc(-c2ccccc2)nc1>>CON(C)C(=O)c1cnc(-c2ccccc2)nc1 -US20050059678A1,6,CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2cc1NC(C)=O>>CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2cc1N -US20130261101A1,6,CC(=O)N1CC(N2Cc3c(F)c(Cl)cc(C4(C)OCCO4)c3OC(C)C2=O)C1>>CC(=O)c1cc(Cl)c(F)c2c1OC(C)C(=O)N(C1CN(C(C)=O)C1)C2 -US05334600,7,COC(=O)c1ccc(-c2ccc(F)cc2)cc1>>OCc1ccc(-c2ccc(F)cc2)cc1 -US08008327B2,6,CCOC(=O)c1cc(C(=O)NCc2ccc(S(=O)(=O)NC)cc2)c2cnn(-c3ccc(F)cc3)c2c1>>CNS(=O)(=O)c1ccc(CNC(=O)c2cc(C(=O)O)cc3c2cnn3-c2ccc(F)cc2)cc1 -US04457924,6,O=C(OCc1ccccc1)[C@@H]1CC[C@@H](C(=O)OCc2ccccc2)CC1>>O=C(O)[C@@H]1CC[C@@H](C(=O)OCc2ccccc2)CC1 -US07151111B2,6,CC(C)(C)OC(=O)NC1CC(=O)N(c2ccc(OCc3ccccc3)cc2)C1>>CC(C)(C)OC(=O)NC1CC(=O)N(c2ccc(O)cc2)C1 -US07601714B2,3,CN(C)C=O.COc1ccncc1>>COc1ccncc1C=O -US20090233910A1,1,CCC(CC)NC(=O)Nc1ccc(Oc2ccc(NC(=O)c3ccc(OC4CCNCC4)cc3)cc2C)cc1.CCC=O>>CCCN1CCC(Oc2ccc(C(=O)Nc3ccc(Oc4ccc(NC(=O)NC(CC)CC)cc4)c(C)c3)cc2)CC1 -US20010014691A1,9,Brc1cncc(OCc2ccccc2)c1.N>>Nc1cncc(OCc2ccccc2)c1 -US08110687B2,6,CC(C)(C)OC(=O)NCc1cc(NC(=O)C2CCc3ccc(Oc4ccnc5[nH]c(=O)ccc45)cc3C2)cc(C(F)(F)F)c1>>NCc1cc(NC(=O)C2CCc3ccc(Oc4ccnc5[nH]c(=O)ccc45)cc3C2)cc(C(F)(F)F)c1 -US20090018134A1,2,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C3CC3)CC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C3CC3)CC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US07417049B2,1,Brc1coc2ccccc12.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1coc2ccccc12 -US07687515B2,3,CCOc1ccc(-c2cc3[nH]c(C[P+](c4ccccc4)(c4ccccc4)c4ccccc4)nc3c(C#N)n2)cc1C(F)(F)F.O=CCCl>>CCOc1ccc(-c2cc3[nH]c(C=CCCl)nc3c(C#N)n2)cc1C(F)(F)F -US05985869,9,Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(Cl)c3ccccc32)cc1.[N-]=[N+]=[N-]>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(N=[N+]=[N-])c3ccccc32)cc1 -US20060135554A1,1,CC(N)CN(C)C.CCN(CC)C(=O)c1ccc(F)c([N+](=O)[O-])c1>>CCN(CC)C(=O)c1ccc(NC(C)CN(C)C)c([N+](=O)[O-])c1 -US20030166708A1,3,CN(C)CC1CCc2ccccc2C1=O.COc1cccc(CCl)c1>>COc1cccc(CC2(O)c3ccccc3CCC2CN(C)C)c1 -US20130303533A1,1,COCCn1ccc2c(Cl)nc(S(=O)(=O)c3ccc(F)cc3)nc21.Nc1cc[nH]n1>>COCCn1ccc2c(Nc3cc[nH]n3)nc(S(=O)(=O)c3ccc(F)cc3)nc21 -US07709471B2,2,CN1CC[C@@H](N)C1.COc1cc(C(=O)Cl)ccc1[N+](=O)[O-]>>COc1cc(C(=O)N[C@@H]2CCN(C)C2)ccc1[N+](=O)[O-] -US07199120B2,8,C#CC(O)c1c(-c2occc2C)nn2c(Cl)cccc12>>C#CC(=O)c1c(-c2occc2C)nn2c(Cl)cccc12 -US20060135771A1,2,C1COCCN1.C[C@H](NC(=O)c1c(CN2CCN(CC(=O)O)C(=O)C2)c(-c2cccs2)nc2ccccc12)C1CCCCC1>>C[C@H](NC(=O)c1c(CN2CCN(CC(=O)N3CCOCC3)C(=O)C2)c(-c2cccs2)nc2ccccc12)C1CCCCC1 -US06468998B1,2,N[C@H]1CCN(CCc2ccccc2)C1.O=C(O)C(c1ccccn1)c1ccccn1>>O=C(N[C@H]1CCN(CCc2ccccc2)C1)C(c1ccccn1)c1ccccn1 -US07781426B2,6,CCOC(=O)C[C@@H]1CC[C@@H](C(=O)N(CC)c2ccc(OC(F)(F)F)cc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)CC1>>CCN(C(=O)[C@@H]1CC[C@@H](CC(=O)O)CC1)c1ccc(OC(F)(F)F)cc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C -US20090074738A1,6,COC(=O)c1ccc(Cn2cc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c3cccc(Cl)c32)cc1>>O=C(O)c1ccc(Cn2cc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c3cccc(Cl)c32)cc1 -US20130040930A1,1,CI.Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCNC4=O)cc3)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCN(C)C4=O)cc3)CC2)c(C)c1 -US05102667,2,CO[C@H](C(=O)O)c1ccccc1.O=C1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12>>CO[C@H](C(=O)N1C[C@@H]2C(=O)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1)c1ccccc1 -US04246269,8,O=C(OCc1ccccc1)N1CC[C@@H](Oc2ccccc2)[C@H](O)C1>>O=C1CN(C(=O)OCc2ccccc2)CCC1Oc1ccccc1 -US08058269B2,7,O=C1Nc2cc(Cl)ccc2/C1=C/c1ccc(Cl)cc1>>O=C1Nc2cc(Cl)ccc2C1Cc1ccc(Cl)cc1 -US04439617,6,COc1ccc2c(C(=O)O)cccc2c1Br>>O=C(O)c1cccc2c(Br)c(O)ccc12 -US06331637B1,2,Cc1noc(N)c1Br.O=S(=O)(Cl)c1ccc(Br)s1>>Cc1noc(NS(=O)(=O)c2ccc(Br)s2)c1Br -US20070249607A1,6,COc1ccc(-c2ccc(C#N)nc2)cc1COCC1(c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1>>COc1ccc(-c2ccc(C#N)nc2)cc1COCC1(c2ccccc2)CCNCC1 -US07612079B2,1,CC(C)n1cnc2c(NCc3ccccc3)nc(F)nc21.CCC(O)[C@H](N)CC>>CCC(O)[C@@H](CC)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1 -US04618683,1,CCI.COc1ccc(Br)c2c1C1C(=O)NC(=O)C1CC2>>CCN1C(=O)C2CCc3c(Br)ccc(OC)c3C2C1=O -US20110053933A1,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.Oc1ncccc1F>>CC(C)(C)OC(=O)N1CCC(Oc2ncccc2F)CC1 -US04097491,2,CCOC(CCNCC1OCC(C)C(C)O1)OCC.O=C(Cl)CBr>>CCOC(CCN(CC1OCC(C)C(C)O1)C(=O)CBr)OCC -US20040167127A1,4,COc1ccc(C(=O)c2cccc(C(F)(F)F)c2F)cc1.NNc1ccc(Br)cc1>>COc1ccc(-c2nn(-c3ccc(Br)cc3)c3c(C(F)(F)F)cccc23)cc1 -US08476470B2,2,CCOC(=O)C12CCC(NCc3ccccc3)(CC1)CC2O.CS(=O)(=O)Cl>>CCOC(=O)C12CCC(NCc3ccccc3)(CC1)CC2OS(C)(=O)=O -US20120225854A1,1,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2COS(C)(=O)=O)cc1)C(F)(F)F.c1c[nH]cn1>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2Cn2ccnc2)cc1)C(F)(F)F -US20050004134A1,2,CNc1nc(-c2ccccc2)c(-c2ccc(=O)n(C(C)C)n2)s1.Cc1cccc(N=C=O)c1>>Cc1cccc(NC(=O)N(C)c2nc(-c3ccccc3)c(-c3ccc(=O)n(C(C)C)n3)s2)c1 -US05646171,1,BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCCCc1nc(C(O)(CC)CC)c(C(=O)OCC)[nH]1>>CCCCc1nc(C(O)(CC)CC)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20090239864A1,1,CN(C)c1ccc([C@H]2CNCCO2)cc1.Cn1c(Cl)nc(-c2ccncc2F)cc1=O>>CN(C)c1ccc([C@H]2CN(c3nc(-c4ccncc4F)cc(=O)n3C)CCO2)cc1 -US20120101082A1,2,CC(C)(C)CCN1CCC(C(=O)O)CC1.Cc1nc2c(o1)-c1ccccc1N(C(=O)c1ccc(CN)c(C)c1)CC2>>Cc1nc2c(o1)-c1ccccc1N(C(=O)c1ccc(CNC(=O)C3CCN(CCC(C)(C)C)CC3)c(C)c1)CC2 -US05840732,1,ClCCSc1cccc2nccn12.O=C1CSC(=O)N1>>O=C1CSC(=O)N1CCSc1cccc2nccn12 -US20150099737A1,2,CC(C)(C)OC(=O)N1C2CCNCC1COC2.CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)O)cn3)nc2n1C1CCCC1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CCC5COCC(C4)N5C(=O)OC(C)(C)C)cn3)nc2n1C1CCCC1 -US08093302B2,7,CCOC(=O)C1CCCCC1c1ccccc1OC>>COc1ccccc1C1CCCCC1CO -US08399465B2,8,CCn1c(CO)cc2cc(Oc3nc4ccccc4s3)ccc21>>CCn1c(C=O)cc2cc(Oc3nc4ccccc4s3)ccc21 -US20080312246A1,6,C[Si](C)(C)C#Cc1cc(Cl)ccc1F>>C#Cc1cc(Cl)ccc1F -US20150119405A1,1,CC1(C)C[C@@H](OS(C)(=O)=O)[C@H](NC(=O)OCC[Si](C)(C)C)CO1.[N-]=[N+]=[N-]>>CC1(C)C[C@H](N=[N+]=[N-])[C@H](NC(=O)OCC[Si](C)(C)C)CO1 -US07902203B2,2,CCCS(=O)(=O)Cl.NCc1csc2c1S(=O)(=O)N=C(c1c(O)c3ccccc3n(NCC3CC3)c1=O)N2>>CCCS(=O)(=O)NCc1csc2c1S(=O)(=O)N=C(c1c(O)c3ccccc3n(NCC3CC3)c1=O)N2 -US08258306B2,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CNOC>>CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 -US20100004238A1,1,CC1(C)NC(=O)c2ccc(O)cc21.O=[N+]([O-])c1ccc(F)c(Cl)c1>>CC1(C)NC(=O)c2ccc(Oc3ccc([N+](=O)[O-])cc3Cl)cc21 -US20120004164A1,2,Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)O.NCc1ncco1>>Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1ncco1 -US20120142705A1,6,COC(=O)C(CC(C)C)N1C(=O)C(=O)c2cc(C)ccc21>>Cc1ccc2c(c1)C(=O)C(=O)N2C(CC(C)C)C(=O)O -US05869694,9,CCOC(=O)C[C@H](O)CCl.[N-]=[N+]=[N-]>>CCOC(=O)C[C@H](O)CN=[N+]=[N-] -US08629270B2,1,Fc1cnc(Cl)nc1.O=C(NC1=NC2(c3ccccc3F)CNCC2CS1)c1ccccc1>>O=C(NC1=NC2(c3ccccc3F)CN(c3ncc(F)cn3)CC2CS1)c1ccccc1 -US06028195,2,Cc1cc(N)c(O)cc1C.O=C(Cl)Oc1ccccc1>>Cc1cc(O)c(NC(=O)Oc2ccccc2)cc1C -US20070167437A1,2,CCOc1nc(C(C)(C)C)ncc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCCN1CCNCC1>>CCOc1nc(C(C)(C)C)ncc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1 -US06525066B2,1,CI.Cc1cc(Br)cc(O)c1C>>COc1cc(Br)cc(C)c1C -US06329380B1,2,CN(c1nccc(-n2cnc3ccccc32)n1)C1CCCNC1.O=C=Nc1cccc2ccccc12>>CN(c1nccc(-n2cnc3ccccc32)n1)C1CCCN(C(=O)Nc2cccc3ccccc23)C1 -US06630487B2,2,CC(C)(C)OC(=O)NC(C)(C)C(=O)NC(COCc1ccccc1)C(=O)O.CN1N=C2CCNC[C@@]2(Cc2ccccc2)C1=O>>CN1N=C2CCN(C(=O)[C@@H](COCc3ccccc3)NC(=O)C(C)(C)NC(=O)OC(C)(C)C)C[C@@]2(Cc2ccccc2)C1=O -US20140018393A1,6,CC(N[C@@H]1C[C@H]1c1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(N[C@@H]1C[C@H]1c1ccccc1)C1CCNCC1 -US07879850B2,6,COC(=O)c1ccc2nc(-c3c(C)cccc3C)[nH]c2c1>>Cc1cccc(C)c1-c1nc2ccc(C(=O)O)cc2[nH]1 -US20040014745A1,2,CS(=O)(=O)Cl.O=C(NC1CCNCC1)c1ccc(F)cc1>>CS(=O)(=O)N1CCC(NC(=O)c2ccc(F)cc2)CC1 -US20060030576A1,2,O=C(O)c1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCOCC4)cc3)n2)cc1.O=C(c1ccco1)N1CCNCC1>>O=C(c1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCOCC4)cc3)n2)cc1)N1CCN(C(=O)c2ccco2)CC1 -US20050107381A1,2,CC(C)[C@H](O)C(=O)O.CCCC(N)C(=O)Nc1cnccn1>>CCCC(NC(=O)C(O)C(C)C)C(=O)Nc1cnccn1 -US08987310B2,2,CC(O)CN.C[C@@H](NC(=O)OC(C)(C)C)C(=O)O>>CC(O)CNC(=O)[C@@H](C)NC(=O)OC(C)(C)C -US07968560B2,2,CCCCCC(=O)Cl.CCO[C@@H](Cc1ccc(-c2csc(CNC)c2)cc1)C(=O)OC>>CCCCCC(=O)N(C)Cc1cc(-c2ccc(C[C@H](OCC)C(=O)OC)cc2)cs1 -US20090253659A1,3,C=CC(=O)OCC.CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(Br)cc2)CC(C)(C)C1>>CCOC(=O)/C=C/c1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(O)cc2)cc1 -US20120232056A1,6,CN(c1nc2cc(C(=O)O)ccc2nc1-c1ccc(F)cc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CN(c1nc2cc(C(=O)O)ccc2nc1-c1ccc(F)cc1)C1CCNCC1 -US20150239920A1,2,NC(=O)c1nn(CC(=O)O)c2cc(O)ccc12.O=C(Nc1cccc(-c2ccccc2Cl)c1F)[C@@H]1C[C@@H](F)CN1>>NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2cc(O)ccc12 -US20060223801A1,6,COC(=O)c1cc(N2CCC(NC(=O)c3[nH]c(C#N)c(Cl)c3Cl)CC2)c2ccccc2n1>>N#Cc1[nH]c(C(=O)NC2CCN(c3cc(C(=O)O)nc4ccccc34)CC2)c(Cl)c1Cl -US07332510B2,1,Cc1cc(B(O)O)ccc1F.Cc1nc(C#Cc2ccnc(Cl)c2)c[nH]1>>Cc1cc(-n2cc(C#Cc3ccnc(Cl)c3)nc2C)ccc1F -US20090054407A1,2,CS(=O)(=O)Cl.O=C1NCc2c(O)ccc(I)c21>>CS(=O)(=O)Oc1ccc(I)c2c1CNC2=O -US08278319B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1CCC2(CCNCC2)CC1>>CC(C)(C)OC(=O)N1CCC2(CCC(=O)CC2)CC1 -US08063044B2,1,CN.N#Cc1ccc(C=O)cc1>>CNCc1ccc(C#N)cc1 -US20090118287A1,6,COC(=O)[C@@H]1C[C@@H](OCc2ccccc2)C1>>COC(=O)[C@H]1C[C@H](O)C1 -US05972975,7,CCCC#Cc1cnc(NC(=O)C(C)(C)C)cc1C>>CCCCCc1cnc(NC(=O)C(C)(C)C)cc1C -US20060211716A1,2,Cc1cccc(N)c1CN.FC(F)(F)c1cccc(N=C=S)c1>>Cc1cccc(N)c1CNC(=S)Nc1cccc(C(F)(F)F)c1 -US07951806B2,2,CNc1ccc(Cl)cc1.COC(=O)c1cc(Cl)ccc1NC(=O)C(CCC(=O)O)NC(=O)OCc1ccccc1>>COC(=O)c1cc(Cl)ccc1NC(=O)C(CCC(=O)N(C)c1ccc(Cl)cc1)NC(=O)OCc1ccccc1 -US07173129B2,2,CC(=O)c1ccc(S(=O)(=O)Cl)cc1.CN>>CNS(=O)(=O)c1ccc(C(C)=O)cc1 -US20050192253A1,7,Cc1c([N+](=O)[O-])ccc2nsnc12>>Cc1c(N)ccc2nsnc12 -US20070213337A1,3,C/C=C\B(O)O.CC(C)(C)OC(=O)N1CCN2C(=O)c3c(cc(Br)cc3C(F)(F)F)[C@@H]2C1>>C/C=C\c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCN(C(=O)OC(C)(C)C)C[C@@H]21 -US20100081680A1,2,O=C1CC2CC(c3cccc(Br)c3)CC(C1)N2.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>O=C1CC2CC(c3cccc(Br)c3)CC(C1)N2S(=O)(=O)c1ccc(C(F)(F)F)cc1 -US20110059957A1,7,O=Cc1ccc(C(=O)O)s1>>O=C(O)c1ccc(CO)s1 -US08188139B2,6,CC(C)(C)OC(=O)N1Cc2ccc(OCC(F)(F)F)cc2C1>>FC(F)(F)COc1ccc2c(c1)CNC2 -US08697723B2,6,COc1cccc(C2CCCNC2)c1>>Oc1cccc(C2CCCNC2)c1 -US20130178625A1,1,CC(C)(C)OC(=O)Nc1cccc(N)c1.O=[N+]([O-])c1c(OS(=O)(=O)C(F)(F)F)ccc2ccccc12>>CC(C)(C)OC(=O)Nc1cccc(Nc2ccc3ccccc3c2[N+](=O)[O-])c1 -US20090137587A1,1,C1=COCCC1.OCCCc1ccc(I)cc1>>Ic1ccc(CCCOC2CCCCO2)cc1 -US20090105295A1,1,CC(=O)Cl.CC(C)Cn1c(CON)nc2c(N)nc3c(c21)CCCC3>>CC(=O)NOCc1nc2c(N)nc3c(c2n1CC(C)C)CCCC3 -US20050032873A1,7,NC(=O)c1ccc(F)c2c1OCC([N+](=O)[O-])C2>>NC(=O)c1ccc(F)c2c1OCC(N)C2 -US20030083359A1,3,COc1cccc(B(O)O)c1.O=C(O)c1cc(C(=O)O)c(C(=O)N(Cc2cccc(Br)c2)[C@H]2CCCc3ccccc32)cc1C(=O)O>>COc1cccc(-c2cccc(CN(C(=O)c3cc(C(=O)O)c(C(=O)O)cc3C(=O)O)[C@H]3CCCc4ccccc43)c2)c1 -US20110117073A1,2,CCC(=O)Cl.CN1CCN(c2cc(Nc3ncc(C#N)s3)nc(SC3CCNCC3)n2)CC1>>CCC(=O)N1CCC(Sc2nc(Nc3ncc(C#N)s3)cc(N3CCN(C)CC3)n2)CC1 -US08048909B2,1,CN.O=Cc1c(F)c(-c2ccccc2)n(S(=O)(=O)c2ccccc2)c1Cl>>CNCc1c(F)c(-c2ccccc2)n(S(=O)(=O)c2ccccc2)c1Cl -US20140155407A1,1,BrCc1cccnc1Br.c1c[nH]cn1>>Brc1ncccc1Cn1ccnc1 -US04950666,2,CC(=O)Cl.NNC(=O)CCCCCCCCCC=C(F)F>>CC(=O)NNC(=O)CCCCCCCCCC=C(F)F -US07514567B2,3,CCCC[Sn](CCCC)(CCCC)c1cncs1.O=C1O[C@]2(CN3CCC2CC3)CN1c1ccc(Br)o1>>O=C1O[C@]2(CN3CCC2CC3)CN1c1ccc(-c2cncs2)o1 -US20120184542A1,2,COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1.NCc1cccc(C(F)(F)F)c1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NCc4cccc(C(F)(F)F)c4)ccc3Cl)c(=O)[nH]c2n1 -US20120142705A1,7,CC(C)CC(C(=O)O)N1C(=O)C(=O)c2ccccc21>>CC(C)CC(C(=O)O)N1C(=O)Cc2ccccc21 -US20120245152A1,6,C[C@@H](OCc1ccccc1)C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1>>C[C@@H](O)C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 -US08937092B2,7,CCS(=O)(=O)NCc1ccc([N+](=O)[O-])cc1>>CCS(=O)(=O)NCc1ccc(N)cc1 -US20100137610A1,2,COC(OC)C(CN)SCc1ccccc1.COCCOc1cc([N+](=O)[O-])c2[nH]c(C(=O)O)cc2c1>>COCCOc1cc([N+](=O)[O-])c2[nH]c(C(=O)NCC(SCc3ccccc3)C(OC)OC)cc2c1 -US20060052365A1,6,CC(C)(C)OC(=O)N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)OCc2ccccc2)CC1O>>N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)OCc2ccccc2)CC1O -US20130065897A1,6,O=C1OCc2cc(-c3ccc(C4OCCO4)s3)ccc21>>O=Cc1ccc(-c2ccc3c(c2)COC3=O)s1 -US05084084,1,CI.O=C1COc2cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)cc2N1>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc3c(cc2F)OCC(=O)N3)c1=O -US20030208066A1,6,CCOC(=O)c1cnc2c(c(C)nn2C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1>>COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C(=O)O)cnc3c2c(C)nn3C)cc1 -US20050245529A1,3,Brc1ccc(Br)nc1.C#CCO>>OCC#Cc1ccc(Br)cn1 -US20130338367A1,6,CCOC(=O)C(CSC)=NOC>>CON=C(CSC)C(=O)O -US20090233956A1,1,COc1cc2c(-c3cc4c(C=O)ccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(C)c2cc1OC.NCCc1ccccc1>>COc1cc2c(-c3cc4c(CNCCc5ccccc5)ccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(C)c2cc1OC -US20120295884A1,9,COc1cc(F)c(F)c(CN=[N+]=[N-])c1>>COc1cc(F)c(F)c(CN)c1 -US20130121994A1,6,COc1ccccc1Nc1nc2ccc(-c3ccc(NC(=O)OC(C)(C)C)cc3)cn2n1>>COc1ccccc1Nc1nc2ccc(-c3ccc(N)cc3)cn2n1 -US20090105266A1,1,CCCN.O=[N+]([O-])c1cc(F)c(F)cc1F>>CCCNc1cc(F)c(F)cc1[N+](=O)[O-] -US20100048570A1,2,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCSC1C(=O)O)Cc1cc(F)c(F)cc1F.NCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCSC1C(=O)NCc1ccccc1)Cc1cc(F)c(F)cc1F -US20150073001A1,2,CC(C)(C)OC(=O)N1CC[C@@H](N)[C@H](O)C1.COc1cc(-c2ncnc3c(C(=O)O)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)cc1F>>COc1cc(-c2ncnc3c(C(=O)N[C@@H]4CCN(C(=O)OC(C)(C)C)C[C@H]4O)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)cc1F -US06800651B2,2,CCS(=O)(=O)Cl.N#Cc1ccccc1Oc1ccc(NCc2cccnc2)cc1>>CCS(=O)(=O)N(Cc1cccnc1)c1ccc(Oc2ccccc2C#N)cc1 -US07759366B2,8,FC(F)(F)c1ccccn1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccccc1C(F)(F)F -US20040209865A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.Ic1ccc(C#CCN2CCCC2)cc1>>Clc1ccc(-c2ccc(C#Cc3ccc(C#CCN4CCCC4)cc3)nc2)cc1 -US08618288B2,9,Cc1ccc(-c2cc(CCN=[N+]=[N-])nc(Cc3ccccc3)n2)cc1>>Cc1ccc(-c2cc(CCN)nc(Cc3ccccc3)n2)cc1 -US04521607,6,CCOC(=O)[C@H](C)NC1CCc2ccccc21>>C[C@H](NC1CCc2ccccc21)C(=O)O -US05132328,1,BrCc1ccc2ccccc2c1.COC(C)(c1cc(O)cc(F)c1)C(C)O>>COC(C)(c1cc(F)cc(OCc2ccc3ccccc3c2)c1)C(C)O -US04432971,6,CCOP(=O)(CCCCc1ccccc1)N(C)CC(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CCOP(=O)(CCCCc1ccccc1)N(C)CC(=O)N1CCC[C@H]1C(=O)O -US04275071,1,Cc1cc(C)c(C)c(C(=O)CBr)c1C.c1c[nH]cn1>>Cc1cc(C)c(C)c(C(=O)Cn2ccnc2)c1C -US20120238540A1,6,CC(C)(C)OC(=O)Nc1ccc(Nc2nccc(-c3ccc(OC4CCOCC4)c(C#N)c3)n2)cc1>>N#Cc1cc(-c2ccnc(Nc3ccc(N)cc3)n2)ccc1OC1CCOCC1 -US20110212956A1,2,CC1NCCc2c1ccc1c2ccn1C.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2ccc3c(ccn3C)c2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US08063046B2,2,COc1ccc(C(N)=O)cc1C(=O)O.COc1ccc(N)c(OC)c1>>COc1ccc(NC(=O)c2cc(C(N)=O)ccc2OC)c(OC)c1 -US20090247514A1,6,CC(C)(C)OC(=O)CC1(C(=O)O)Cc2ccccc2C1>>O=C(O)CC1(C(=O)O)Cc2ccccc2C1 -US04939259,1,CCCN1CCC[C@H]2Cc3nc(Cl)ccc3C[C@@H]21.NCc1ccccc1>>CCCN1CCC[C@H]2Cc3nc(NCc4ccccc4)ccc3C[C@@H]21 -US06528543B1,2,CCOC(=O)C(CC1CCCC1)c1ccccc1.CNC(N)=O>>CNC(=O)NC(=O)C(CC1CCCC1)c1ccccc1 -US20150011461A1,5,CC(C)(C)OC(=O)C1CCC(=O)N1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)C1CCC(=O)N1C(=O)OC(C)(C)C -US20110245224A1,9,CCOC(=O)C(=O)c1cc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F.NO>>CCOC(=O)C(=NO)c1cc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F -US20040033995A1,2,COC(=O)C=CC(N)Cc1cn(Cc2ccccc2)c2ccccc12.O=C(O)CCCCCCc1ccccc1>>COC(=O)C=C[C@@H](Cc1cn(Cc2ccccc2)c2ccccc12)NC(=O)CCCCCCc1ccccc1 -US20090111815A1,2,CCOC(=O)c1c(O)c(F)c(C)n(C)c1=O.Nc1ccc(Cl)nn1>>Cc1c(F)c(O)c(C(=O)Nc2ccc(Cl)nn2)c(=O)n1C -US20110281854A1,1,C[C@@H]1CN[C@H](c2ccccc2)CO1.O=C1COc2cnc(Cl)cc2N1>>C[C@@H]1CN(c2cc3c(cn2)OCC(=O)N3)[C@H](c2ccccc2)CO1 -US20120316150A1,1,CC(C)(C)OC(=O)NN.O=C1CCOC1>>CC(C)(C)OC(=O)N/N=C1\CCOC1 -US06642239B2,2,CCCN1CCC(c2ccc(C(=O)O)cc2)CC1.N#CCNC(=O)C1(N)CCCCC1>>CCCN1CCC(c2ccc(C(=O)NC3(C(=O)NCC#N)CCCCC3)cc2)CC1 -US04350822,7,O=C(O)CCCc1cccs1>>OCCCCc1cccs1 -US07538931B2,1,CCCI.c1ccc(CNCc2ccccn2)nc1>>CCCN(Cc1ccccn1)Cc1ccccn1 -US20070249670A1,7,CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(S(C)(=O)=O)cc1[N+](=O)[O-])C1CCCCC1>>CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(S(C)(=O)=O)cc1N)C1CCCCC1 -US04399296,2,CC(=O)[O-].Nc1ccccc1C1OC(=O)NC1=O>>CC(=O)Nc1ccccc1C1OC(=O)NC1=O -US07232832B2,6,COc1ccc2nccc(C#C[Si](C)(C)C)c2n1>>C#Cc1ccnc2ccc(OC)nc12 -US07381719B2,1,CC(C)CCN.NC(=O)c1cnc(Oc2ccc(C=O)cc2)cn1>>CC(C)CCNCc1ccc(Oc2cnc(C(N)=O)cn2)cc1 -US08129376B2,2,NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1.O=C(O)c1cc(-c2ccc(O)cc2)on1>>O=C(NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1)c1cc(-c2ccc(O)cc2)on1 -US05206229,6,CC(C)(CCCCCBr)O[Si](C)(C)C>>CC(C)(O)CCCCCBr -US04990664,2,CCN(CC)C(=O)c1ccc(CCCCO)cc1.CS(=O)(=O)Cl>>CCN(CC)C(=O)c1ccc(CCCCOS(C)(=O)=O)cc1 -US05089487,8,COc1c([C@@H](O)CC(C)C)ccc2c1C(=O)OCc1cc(C)cc(O)c1O2>>COc1c(C(=O)CC(C)C)ccc2c1C(=O)OCc1cc(C)cc(O)c1O2 -US20130210768A1,3,CC1(C)OB(c2ccccc2C#N)OC1(C)C.Cn1c(=O)n(CC2CC2)c2ccc(Cl)nc21>>Cn1c(=O)n(CC2CC2)c2ccc(-c3ccccc3C#N)nc21 -US20070197571A1,1,CC(C#N)Cc1cccc(C=O)c1.O=C1N=C(NC2CCCCC2)C2(CCNCC2)N1c1cccc(F)c1>>CC(C#N)Cc1cccc(CN2CCC3(CC2)C(NC2CCCCC2)=NC(=O)N3c2cccc(F)c2)c1 -US20120190738A1,8,CC(C)(CO)c1ccc2c(c1)OCO2>>CC(C)(C=O)c1ccc2c(c1)OCO2 -US20090325930A1,7,CCOC(=O)c1ccc(OCCN2CCCCC2)cc1>>OCc1ccc(OCCN2CCCCC2)cc1 -US08722702B2,7,C=C(c1ccc(NCc2ccc(C(F)(F)F)cc2)nc1)c1c[nH]c2ncccc12>>CC(c1ccc(NCc2ccc(C(F)(F)F)cc2)nc1)c1c[nH]c2ncccc12 -US20120302551A1,9,COC(=O)C1CC(=O)Nc2cc(C(F)(F)F)ccc2C1=O>>O=C1CCC(=O)c2ccc(C(F)(F)F)cc2N1 -US08129376B2,2,FC(F)(F)c1ccccc1OC1CCNCC1.O=C(O)CNC(=O)c1cn(-c2cccnc2)nn1>>O=C(NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1)c1cn(-c2cccnc2)nn1 -US06794395B1,2,CC(=O)OC(C)=O.COc1cc2c(cc1OC)/C(=C(/Nc1ccccc1)c1cccc(CN)c1)C(=O)N2>>COc1cc2c(cc1OC)/C(=C(/Nc1ccccc1)c1cccc(CNC(C)=O)c1)C(=O)N2 -US20060183762A1,6,CCOC(=O)c1cc(Cl)c(N2CCC(NC(=O)OC(C)(C)C)C2)c(F)c1NC1CC1>>CC(C)(C)OC(=O)NC1CCN(c2c(Cl)cc(C(=O)O)c(NC3CC3)c2F)C1 -US20150225422A1,1,CI.Cc1c(Br)cnc(Cl)c1N>>CNc1c(Cl)ncc(Br)c1C -US06028082,3,C1COCCN1.O=C1CCN(Cc2ccccc2)CC1.[C-]#N>>N#CC1(N2CCOCC2)CCN(Cc2ccccc2)CC1 -US20040063699A1,7,O=C(N1CCc2ccc([N+](=O)[O-])cc2CC1)C(F)(F)F>>Nc1ccc2c(c1)CCN(C(=O)C(F)(F)F)CC2 -US07803822B2,2,CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(N)cc1.CN(C)CC(=O)O>>CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(NC(=O)CN(C)C)cc1 -US20100184815A1,2,COC(=O)[C@@H](C)OCc1ccccc1.NN>>C[C@@H](OCc1ccccc1)C(=O)NN -US20100056507A1,2,CC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1.NNC(=O)CCc1ccc([N+](=O)[O-])cc1>>CC(C)(C)c1cc(C(=O)NNC(=O)CCc2ccc([N+](=O)[O-])cc2)cc(C(C)(C)C)c1 -US03931268,2,CN(C(=O)OCc1ccccc1)N(Cc1ccc(C(=O)Cl)cc1)C(=O)OCc1ccccc1.CNC(N)=O>>CNC(=O)NC(=O)c1ccc(CN(C(=O)OCc2ccccc2)N(C)C(=O)OCc2ccccc2)cc1 -US20070225349A1,1,CC(C)(C)OC(=O)NCC(=O)NCC(=O)O.Oc1ccc(-c2nn(C3CCCC3)c3c(F)cccc23)cc1>>CC(C)(C)OC(=O)NCC(=O)NCC(=O)Oc1ccc(-c2nn(C3CCCC3)c3c(F)cccc23)cc1 -US20150284411A1,3,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4nc(Cl)ncc4n3COCC[Si](C)(C)C)CO[C@@H]21.OB(O)c1ccc(-c2ccccc2)cc1>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)ncc4n3COCC[Si](C)(C)C)CO[C@@H]21 -US06432963B1,2,CC(=O)Oc1ccccc1/C=C\C(=O)O.Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ncc2C(N)=O)c1>>CC(=O)Oc1ccccc1/C=C\C(=O)N[C@@H]1CCCC[C@@H]1Nc1ncc(C(N)=O)c(Nc2cccc(C)c2)n1 -US04370340,7,O=C1Cc2cc([N+](=O)[O-])c(Cl)cc2N1>>Nc1cc2c(cc1Cl)NC(=O)C2 -US20080070928A1,4,CS(=O)(=O)c1ccc(Oc2cc(N)c(N)cc2Oc2cccnc2OC(F)F)cn1.Cc1cnc(C(=O)O)cn1>>Cc1cnc(-c2nc3cc(Oc4cccnc4OC(F)F)c(Oc4ccc(S(C)(=O)=O)nc4)cc3[nH]2)cn1 -US06232313B1,1,O=C1NC(=O)c2ccccc21.O=c1c2ccc(Cl)cc2[nH]c2c(O)nn(CCBr)c(=O)c12>>O=C1c2ccccc2C(=O)N1CCn1nc(O)c2[nH]c3cc(Cl)ccc3c(=O)c2c1=O -US20130338157A1,1,CI.COc1cc(N2CCN(C(=O)Cn3nc(-c4ncc[nH]4)c4cccnc43)CC2)ccc1Cl>>COc1cc(N2CCN(C(=O)Cn3nc(-c4nccn4C)c4cccnc43)CC2)ccc1Cl -US08318928B2,2,CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)O)cccc1OC(F)F.Nc1nc2c(s1)CCC2>>CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)Nc2nc3c(s2)CCC3)cccc1OC(F)F -US04471116,1,CC(C)NC[C@H](O)COc1ccc(O)cc1.ClCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1>>CC(C)NC[C@H](O)COc1ccc(OCCN2CCN(CCCN3c4ccccc4Sc4ccc(Cl)cc43)CC2)cc1 -US08962627B2,3,C=C[Sn](CCCC)(CCCC)CCCC.CC(C)(C)ON=c1cc(-c2cc3ccccc3cn2)oc2ccc(Br)cc12>>C=Cc1ccc2oc(-c3cc4ccccc4cn3)cc(=NOC(C)(C)C)c2c1 -US04814346,6,CC(=O)Nc1ccc(-c2coc3cc(OC(C)=O)c(O)cc3c2=O)cc1>>CC(=O)Nc1ccc(-c2coc3cc(O)c(O)cc3c2=O)cc1 -US20130158075A1,2,Nc1ccc(-c2cnc(CNS(=O)(=O)C(F)(F)F)s2)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccc(-c2cnc(CNS(=O)(=O)C(F)(F)F)s2)cc1)c1ccccc1 -US20150252044A1,3,COCCNC(=O)c1ccc2cncc(Br)c2n1.OB(O)c1ccccc1Cl>>COCCNC(=O)c1ccc2cncc(-c3ccccc3Cl)c2n1 -US20100105661A1,1,N#Cc1ccccc1C=O.NC(=O)c1cnc2[nH]ccc2c1NC1CCNCC1>>N#Cc1ccccc1CN1CCC(Nc2c(C(N)=O)cnc3[nH]ccc23)CC1 -US20030109532A1,1,CC(=O)c1cccc(N2C[C@H](C)N[C@H](C)C2)c1.CCCI>>CCCN1[C@@H](C)CN(c2cccc(C(C)=O)c2)C[C@H]1C -US20110263571A1,3,CB(O)O.CCc1cc(Br)ccc1N1CCN(S(=O)(=O)c2ccc(C)cc2)CC1>>CCc1cc(C)ccc1N1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 -US20100152230A1,1,CCCCCc1cc(Cl)c([N+](=O)[O-])c(Cl)n1.NCC1CCOCC1>>CCCCCc1cc(NCC2CCOCC2)c([N+](=O)[O-])c(Cl)n1 -US09040545B2,7,Cn1cc(Nc2ncc3cnn(Cc4cccc(C5=CCOCC5)c4)c3n2)cn1>>Cn1cc(Nc2ncc3cnn(Cc4cccc(C5CCOCC5)c4)c3n2)cn1 -US07919506B2,9,BrC(Br)(Br)Br.CO[C@H](c1ccc(C(F)(F)F)cc1CO)C1CCCCC1>>CO[C@H](c1ccc(C(F)(F)F)cc1CBr)C1CCCCC1 -US06610707B1,9,CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)O.N>>CC(C)(C)OC(=O)N1CCCC[C@H]1C(N)=O -US20070027163A1,2,Fc1ccccc1N1CCNCC1.O=C(O)c1c[nH]c2cc(Cl)ccc12>>O=C(c1c[nH]c2cc(Cl)ccc12)N1CCN(c2ccccc2F)CC1 -US07544703B2,1,CN1CCNCC1.Cc1cc(C)cc(NC(=O)c2cccnc2SCc2ccnc(F)c2)c1>>Cc1cc(C)cc(NC(=O)c2cccnc2SCc2ccnc(N3CCN(C)CC3)c2)c1 -US20150166480A1,1,CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)CC1.N#Cc1cc(Br)ccc1O>>CC(C)(C)OC(=O)N1CCC(COc2ccc(Br)cc2C#N)CC1 -US20090306053A1,2,C[C@@H](NC(=O)OC(C)(C)C)C(=O)O.O=S(=O)(c1cccc2cnccc12)N1CCCNCC1>>C[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CCCN(S(=O)(=O)c2cccc3cnccc23)CC1 -US06713508B2,1,BrCc1ccccc1.CCOC(=O)C1CCc2ccc(O)cc2O1>>CCOC(=O)C1CCc2ccc(OCc3ccccc3)cc2O1 -US20030144319A1,7,Nc1ccc(OCCN2CCc3ccccc3C2)cc1[N+](=O)[O-]>>Nc1ccc(OCCN2CCc3ccccc3C2)cc1N -US07384965B2,3,CCOC(=O)c1ccc2nc(Br)sc2c1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1ccc2nc(-c3ccc(C(F)(F)F)cc3)sc2c1 -US07985755B2,7,O=C(O)C1CCC(Cc2cccc(Cl)c2)CC1>>OCC1CCC(Cc2cccc(Cl)c2)CC1 -US05521177,6,CCc1nc2c(C)cc(NC(=NS(=O)(=O)c3ccccc3)N(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CCc1nc2c(C)cc(NC(=NS(=O)(=O)c3ccccc3)N(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20130085143A1,6,COC(=O)C(Cc1ccccc1)NC(=O)Cc1cc(C)cc(C)c1>>Cc1cc(C)cc(CC(=O)NC(Cc2ccccc2)C(=O)O)c1 -US20150183801A1,3,O=C(Nc1ccc(S(=O)(=O)C(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(Cl)c1.OB(O)c1cncnc1>>O=C(Nc1ccc(S(=O)(=O)C(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1 -US20110046137A1,1,CCOc1cccc(Br)n1.O=C(Cc1cn[nH]c1)NCc1ccc(F)cc1Cl>>CCOc1cccc(-n2cc(CC(=O)NCc3ccc(F)cc3Cl)cn2)n1 -US20150045378A1,6,CCOC(=O)CC(c1ccnc(OC)c1)C1CC1>>CCOC(=O)CC(c1ccnc(O)c1)C1CC1 -US20080306115A1,2,Cc1c(C(=O)O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1.Cc1ccc(N)nc1>>Cc1ccc(NC(=O)c2nc(-c3ccc(Cl)cc3Cl)n(-c3ccc(OCc4ccccc4)cc3)c2C)nc1 -US09157077B2,1,C1CCNCC1.O=C1NC(=O)/C(=C/c2cccc(Br)n2)S1>>O=C1NC(=O)/C(=C/c2cccc(N3CCCCC3)n2)S1 -US20110003820A1,2,CC1NCCn2cc(-c3nn[nH]n3)cc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2cc(-c3nn[nH]n3)cn2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US20120302566A1,1,COC(=O)C[C@@H]1COc2cc(O)ccc21.COC1(c2cccc3c2CC[C@@H]3O)CCC1>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3cccc4C3(OC)CCC3)ccc21 -US20080262064A1,2,CCC1(C)CCC(C(C)(C)O)O1.O=C(Cl)CBr>>CCC1(C)CCC(C(C)(C)OC(=O)CBr)O1 -US20150057260A1,9,CCOC(=O)c1nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)nc2ccc(OC)cc12.N>>COc1ccc2nc(-c3cccc(C#C[C@]4(O)CCN(C)C4=O)c3)nc(C(N)=O)c2c1 -US07135487B2,3,CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(C=O)cc2)cc1.CC[Mg+]>>CCC(O)c1ccc(-c2ccc(C(C)CNS(=O)(=O)C(C)C)cc2)cc1 -US05112847,8,CC(C)C(CCCCc1ccccc1)C(=O)N1CCC[C@H]1CO>>CC(C)C(CCCCc1ccccc1)C(=O)N1CCC[C@H]1C=O -US20140213586A1,1,COc1cccc(N)c1.O=Cc1cncnc1>>COc1cccc(N=Cc2cncnc2)c1 -US08975288B2,2,CCCn1nnnc1N.O=C(O)C1CCCC1>>CCCn1nnnc1NC(=O)C1CCCC1 -US20100311966A1,2,CC(C)(C)OC(=O)N1CC[C@@H](N)[C@H](O)C1.CCc1[nH]c(C(=O)O)nc1Cl>>CCc1[nH]c(C(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2O)nc1Cl -US20120101100A1,3,CCNC(=O)Nc1cc(-c2nc(-c3cccc(OC)n3)cs2)c(B(O)O)cn1.O=C(O)c1cncc(Cl)n1>>CCNC(=O)Nc1cc(-c2nc(-c3cccc(OC)n3)cs2)c(-c2cncc(C(=O)O)n2)cn1 -US09102625B2,1,Cc1cccc(N)c1.N#Cc1cnc(Cl)cc1NCc1ccccc1>>Cc1cccc(Nc2cc(NCc3ccccc3)c(C#N)cn2)c1 -US07005440B1,3,CCOC(=O)c1c(C)cccc1COc1cccc(OCc2cccc(Cl)n2)c1.OB(O)c1ccccc1>>CCOC(=O)c1c(C)cccc1COc1cccc(OCc2cccc(-c3ccccc3)n2)c1 -US05840745,2,CO.O=C1Nc2ccc(C(=O)O)cc2C1=Cc1ccnc2ccccc12>>COC(=O)c1ccc2c(c1)C(=Cc1ccnc3ccccc13)C(=O)N2 -US20110217311A1,2,CS(=O)(=O)Cl.N[C@@H]1CC[C@@H](Oc2cc(F)ccc2[N+](=O)[O-])CC1>>CS(=O)(=O)N[C@@H]1CC[C@@H](Oc2cc(F)ccc2[N+](=O)[O-])CC1 -US20120270865A2,2,CNOC.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>CON(C)C(=O)c1cc2cc(Cl)ccc2[nH]1 -US20090149439A1,3,CCOc1ccc(SC(c2cnc(Br)cc2C)c2cc(F)ccc2F)cc1.CN(C)C=O>>CCOc1ccc(SC(c2cnc(C=O)cc2C)c2cc(F)ccc2F)cc1 -US20150080396A1,2,CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(C(=O)O)cc1OC.CN(C)CCCCO>>CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(C(=O)OCCCCN(C)C)cc1OC -US20140194408A1,7,Cn1cc(-c2ccnc(N3CCn4c(cc5c4CC(C)(C)C5)C3=O)c2C=O)cc(Nc2cc3n(n2)CCN(C2COC2)C3)c1=O>>Cn1cc(-c2ccnc(N3CCn4c(cc5c4CC(C)(C)C5)C3=O)c2CO)cc(Nc2cc3n(n2)CCN(C2COC2)C3)c1=O -US07071175B1,2,CC(=O)OC(C)=O.Cc1ccnc(N)c1>>CC(=O)Nc1cc(C)ccn1 -US20100105683A1,1,Cc1ccc(O)c([N+](=O)[O-])c1.OCCN1CC1>>Cc1ccc(OCCN2CC2)c([N+](=O)[O-])c1 -US05310743,6,O=C(c1ccccc1Cl)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1>>O=C(c1ccccc1Cl)N1CC[C@H](NCc2ccnc3ccccc23)C[C@H]1Cc1ccccc1 -US20150141400A1,7,CCSc1ccc(C(F)(F)F)cc1C#N>>CCSc1ccc(C(F)(F)F)cc1CN -US20040010009A1,9,Cc1cc([N+](=O)[O-])cc(C(=O)O)c1OC1CCN(C(=O)OC(C)(C)C)CC1.N>>Cc1cc([N+](=O)[O-])cc(C(N)=O)c1OC1CCN(C(=O)OC(C)(C)C)CC1 -US20070066639A1,7,CC(=O)OCCCNc1c(C)c(C)n2nnnc2c1[N+](=O)[O-]>>CC(=O)OCCCNc1c(C)c(C)n2nnnc2c1N -US05010077,2,CN.O=C(O)c1cc2c(cn1)[nH]c1ccccc12>>CNC(=O)c1cc2c(cn1)[nH]c1ccccc12 -US20020165234A1,6,COc1ccc(F)c2[nH]c3ccccc3c12>>Oc1ccc(F)c2[nH]c3ccccc3c12 -US04921855,8,O=C(OCc1ccccc1)[C@H](Cc1ccccc1)OC(=O)N1CCSC1.O=C(OO)c1cccc(Cl)c1>>O=C(OCc1ccccc1)[C@H](Cc1ccccc1)OC(=O)N1CCS(=O)C1 -US20060074237A1,2,Nc1cccc(COCC(F)(F)F)n1.O=S(=O)(Cl)c1cc(C(F)(F)F)ccc1Cl>>O=S(=O)(Nc1cccc(COCC(F)(F)F)n1)c1cc(C(F)(F)F)ccc1Cl -US05958918,2,N#Cc1cccc(CN2CC[C@H](N)C2=O)c1.O=S(=O)(Cl)/C=C/c1ccccc1>>N#Cc1cccc(CN2CC[C@H](NS(=O)(=O)C=Cc3ccccc3)C2=O)c1 -US09000044B2,3,COC(=O)Cc1cc2ccc(Cl)cc2c(B2OC(C)(C)C(C)(C)O2)c1C.FC(F)(F)Oc1ccc(Sc2ccc(Br)cc2)cc1>>COC(=O)Cc1cc2ccc(Cl)cc2c(-c2ccc(Sc3ccc(OC(F)(F)F)cc3)cc2)c1C -US20060142333A1,6,COCCOc1cc(C(=O)OC)ccc1-c1ccc(F)cc1>>COCCOc1cc(C(=O)O)ccc1-c1ccc(F)cc1 -US07745438B2,3,CC(C)(C)CO[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](C=O)CO1.O=[N+]([O-])CCc1cc(F)cc(F)c1>>CC(C)(C)CO[C@H]1CN(C(=O)OC(C)(C)C)[C@@H]([C@@H](O)[C@H](Cc2cc(F)cc(F)c2)[N+](=O)[O-])CO1 -US05428043,6,COc1ccc2c(c1)cc1n2CC(CC2CCN(Cc3ccccc3)CC2)C1=O>>O=C1c2cc3cc(O)ccc3n2CC1CC1CCN(Cc2ccccc2)CC1 -US20080200448A1,2,CC(C)(C)c1ccc(CS(N)(=O)=O)cc1.CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCCC1=O>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccc(C(C)(C)C)cc3)CC2)nc1CN1CCCCC1=O -US20030055251A1,7,CC(C)(C)OC(=O)N1C=CC2(CC1)c1ccccc1C(=O)N2Cc1ccccc1>>CC(C)(C)OC(=O)N1CCC2(CC1)c1ccccc1C(=O)N2Cc1ccccc1 -US20140249162A1,6,COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2c(c(C)c(C)n2Cc2ccncc2)c1-c1ccc(Cl)cc1>>Cc1nc2c(c(C)c(C)n2Cc2ccncc2)c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O -US20050245432A1,1,BrCc1ccccc1.CN(C(=O)OCc1ccccc1)[C@@H](CCCCO)C(=O)O>>CN(C(=O)OCc1ccccc1)[C@@H](CCCCO)C(=O)OCc1ccccc1 -US20100035953A1,1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.OCc1cc(-c2ccc(OC(F)(F)F)cc2)n(C(F)F)n1>>CCOC(=O)C(C)(C)Oc1ccc(OCc2cc(-c3ccc(OC(F)(F)F)cc3)n(C(F)F)n2)cc1C -US05817678,4,C[S+](C)(C)=O.O=C(c1ccccc1)c1cccc(Cl)c1>>Clc1cccc(C2(c3ccccc3)CO2)c1 -US20090170916A1,7,CCOC(=O)c1cc(C(=O)CCc2ccccc2)c[nH]1>>CCOC(=O)c1cc(CCCc2ccccc2)c[nH]1 -US08067446B2,6,COC(=O)c1ccnc(-c2ccc(-n3cccc3)c(C#N)c2)c1>>N#Cc1cc(-c2cc(C(=O)O)ccn2)ccc1-n1cccc1 -US04673746,6,CCOC(=O)C(CC)Oc1ccc2c(-c3ccc(Cl)cc3)noc2c1>>CCC(Oc1ccc2c(-c3ccc(Cl)cc3)noc2c1)C(=O)O -US20070219235A1,6,CC(C)(C)OC(=O)NC1CCN(c2cc3[nH]c(Nc4ccccc4C(F)(F)F)nc3cc2C(=O)Nc2ccc3cn[nH]c3c2)CC1>>NC1CCN(c2cc3[nH]c(Nc4ccccc4C(F)(F)F)nc3cc2C(=O)Nc2ccc3cn[nH]c3c2)CC1 -US08329682B2,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN(C)C)CCC2.O=C1Cc2c(cccc2-c2cccc(F)c2)N1>>Cc1c(/C=C2\C(=O)Nc3cccc(-c4cccc(F)c4)c32)[nH]c2c1C(=O)N(CCN(C)C)CCC2 -US20150225388A1,2,NCCC(F)(F)F.[N-]=[N+]=Nc1ccc(C(=O)O)cc1>>[N-]=[N+]=Nc1ccc(C(=O)NCCC(F)(F)F)cc1 -US08685989B2,1,CCOC(=O)CN.Clc1cnnc(Cl)c1Cl>>CCOC(=O)CNc1cnnc(Cl)c1Cl -US20130231333A1,3,CCC#C[Si](C)(C)C.Fc1nn(C2CCCCO2)c2ccc(Br)cc12>>CCC#Cc1ccc2c(c1)c(F)nn2C1CCCCO1 -US07407963B2,3,COC(=O)/C=C/C(=O)c1cc(Br)c(N)c(Br)c1.C[S+](C)(C)=O>>COC(=O)[C@@H]1C[C@H]1C(=O)c1cc(Br)c(N)c(Br)c1 -US20140228361A1,1,C=O.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CC2CNCC2C1>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CC2CN(C)CC2C1 -US20040068135A1,4,C=C(C)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1.OO>>CC1(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)CO1 -US20150203515A1,7,C[C@@H]1CC[C@H](Oc2ccc3cc(C=O)ccc3c2C(F)(F)F)CC1>>C[C@@H]1CC[C@H](Oc2ccc3cc(CO)ccc3c2C(F)(F)F)CC1 -US20070037807A1,6,COC(=O)Cc1c(C)nc(CC(C)C)c(CNC(=O)OC(C)(C)C)c1-c1ccc(C)cc1>>Cc1ccc(-c2c(CC(=O)O)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1 -US20040224939A1,9,[N-]=[N+]=NCC1CN(c2ccc3c(c2)CC(=O)CCC3)C(=O)O1>>NCC1CN(c2ccc3c(c2)CC(=O)CCC3)C(=O)O1 -US20090176837A1,2,Cc1cc(C(=O)O)ccc1Br.N#CCCO>>Cc1cc(C(=O)OCCC#N)ccc1Br -US20110144033A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)NN1CCC(C(=O)O)CC1>>CC(C)(C)OC(=O)NN1CCC(C(=O)OCc2ccccc2)CC1 -US06197804B1,3,O=C1Cc2c(ccc([N+](=O)[O-])c2F)N1.O=Cc1ccc[nH]1>>O=C1Nc2ccc([N+](=O)[O-])c(F)c2/C1=C/c1ccc[nH]1 -US04150137,2,CC(C)Cc1ccc(C(C)C(=O)O)cc1.CCCO>>CCCOC(=O)C(C)c1ccc(CC(C)C)cc1 -US06881728B1,8,COc1ccc2c(c1)C[C@@H](C)[C@@H]1[C@@H]2CC[C@]2(C)[C@H](CO)CC[C@H]12>>COc1ccc2c(c1)C[C@@H](C)[C@@H]1[C@@H]2CC[C@]2(C)[C@H](C=O)CC[C@H]12 -US07560558B2,1,COc1cc2nccc(Cl)c2cc1OC.Oc1cc2cccnc2nc1-c1ccccc1>>COc1cc2nccc(Oc3cc4cccnc4nc3-c3ccccc3)c2cc1OC -US06492539B1,3,CC1Cc2cccc(Cl)c2C1=O.OB(O)c1cccc2ccccc12>>CC1Cc2cccc(-c3cccc4ccccc34)c2C1=O -US20110212053A1,1,CO.Clc1ccc2cc(Br)ccc2n1>>COc1ccc2cc(Br)ccc2n1 -US05536727,1,CN1C(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4O)[C@@H]3CC[C@@H]12.O=[N+]([O-])c1ccc(F)cc1>>CN1C(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4Oc4ccc([N+](=O)[O-])cc4)[C@@H]3CC[C@@H]12 -US20130331378A1,6,COC(=O)c1c(-c2ccccc2)nn2cc(OC)ccc12>>COc1ccc2c(C(=O)O)c(-c3ccccc3)nn2c1 -US20030055244A1,6,CCOC(=O)CCN1CCN(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1=O>>O=C(O)CCN1CCN(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1=O -US20110124634A1,3,COc1c(C)cnc(CN2C(=O)Cc3c(Cl)nc(N)nc32)c1C.Cc1c(C=O)[nH]c(Cl)c1C(=O)NCCN1CCCC1>>COc1c(C)cnc(CN2C(=O)/C(=C\c3[nH]c(Cl)c(C(=O)NCCN4CCCC4)c3C)c3c(Cl)nc(N)nc32)c1C -US07022851B2,2,Cc1cc(Cl)cc([N+](=O)[O-])c1S(=O)(=O)N1CCNCC1=O.Cc1cn(CC(=O)O)c(=O)[nH]c1=O>>Cc1cc(Cl)cc([N+](=O)[O-])c1S(=O)(=O)N1CCN(C(=O)Cn2cc(C)c(=O)[nH]c2=O)CC1=O -US07696201B2,1,CI.O=C1Nc2ccccc2C2(CCN(C3CCCCCC3)CC2)O1>>CN1C(=O)OC2(CCN(C3CCCCCC3)CC2)c2ccccc21 -US08586604B2,2,CC(C)(C)C(=O)NCc1ccc(Cl)c(N=C=S)c1Cl.Nc1cc(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)c(OCC(F)F)nc1N>>CC(C)(C)C(=O)NCc1ccc(Cl)c(NC(=S)Nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(OCC(F)F)nc2N)c1Cl -US20030171584A1,1,CCOC(=S)c1cnc(C)nc1Cl.CN>>CCOC(=S)c1cnc(C)nc1NC -US20070293521A1,1,Fc1cnc(Cl)nc1Cl.Nc1ccc(Cl)nc1>>Fc1cnc(Cl)nc1Nc1ccc(Cl)nc1 -US07595331B2,7,CC(NC(=O)CC1CCN(Cc2ccc(F)cc2)CC1)c1ccccc1>>CC(NCCC1CCN(Cc2ccc(F)cc2)CC1)c1ccccc1 -US20110319378A1,3,C=CCC[Mg+].O=C(Cl)c1cccc(Cl)c1>>C=CCCC(=O)c1cccc(Cl)c1 -US20050215555A1,1,CS(=O)(=O)OCCCN1C(=O)C2CCCCC2C1=O.Fc1ccc(-c2nc(C3CCNCC3)n3ccccc23)cc1>>O=C1C2CCCCC2C(=O)N1CCCN1CCC(c2nc(-c3ccc(F)cc3)c3ccccn23)CC1 -US05256824,9,ClC(Cl)(Cl)Cl.OC1C=CC(c2ccccc2)(c2ccccc2)C1>>ClC1C=CC(c2ccccc2)(c2ccccc2)C1 -US20050032873A1,1,CC=O.COc1cccc2c1CC(NCCCCc1coc3ccccc13)CO2>>CCN(CCCCc1coc2ccccc12)C1COc2cccc(OC)c2C1 -US04863942,7,CCCc1c(OCCCOc2cc([N+](=O)[O-])c(C)cc2Br)ccc(C(C)=O)c1O>>CCCc1c(OCCCOc2cc(N)c(C)cc2Br)ccc(C(C)=O)c1O -US20110190269A1,1,COc1cc(Br)ccc1-n1cnc(C)c1.CS(=O)(=O)N1Cc2nc(N)nn2C(c2ccc(F)cc2)C1>>COc1cc(Nc2nc3n(n2)C(c2ccc(F)cc2)CN(S(C)(=O)=O)C3)ccc1-n1cnc(C)c1 -US20140213580A1,1,CC(C)[C@@H]1CN(c2nc(C3CC3)c(N)cc2C#N)CCN1C(=O)OC(C)(C)C.Clc1ccnc(Br)c1>>CC(C)[C@@H]1CN(c2nc(C3CC3)c(Nc3cc(Cl)ccn3)cc2C#N)CCN1C(=O)OC(C)(C)C -US20120225859A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Clc1cc(Cl)nc(N2CCOCC2)n1>>CC(C)(C)OC(=O)N1CCC(Oc2cc(Cl)nc(N3CCOCC3)n2)CC1 -US03932452,1,ClCc1ccc(OCc2ccccc2)cc1.O=C1NCCN1>>O=C1NCCN1Cc1ccc(OCc2ccccc2)cc1 -US05889002,2,CC(C)N=C=S.Nc1cc(Cl)sc1S(N)(=O)=O>>CC(C)NC(=S)NS(=O)(=O)c1sc(Cl)cc1N -US20100130538A1,7,COC(=O)c1c(F)ccc([N+](=O)[O-])c1C>>COC(=O)c1c(F)ccc(N)c1C -US06162791,1,COC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)Nc1nc(CCl)ns1.c1ccc(N2CCNCC2)nc1>>COC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)Nc1nc(CN2CCN(c3ccccn3)CC2)ns1 -US05698696,1,BrCc1ccccc1.Cc1c(C)c2c(c(C)c1O)C(=O)C(C)(C)O2>>Cc1c(C)c2c(c(C)c1OCc1ccccc1)C(=O)C(C)(C)O2 -US20060128700A1,1,C1CC2COCC(C1)N2.N#CCBr>>N#CCN1C2CCCC1COC2 -US20140194431A1,9,CS(=O)(=O)OCC1(c2cccc3ccccc23)CCCC1.[C-]#N>>N#CCC1(c2cccc3ccccc23)CCCC1 -US20030199578A1,2,Cc1ccc(C(=O)Cl)cc1.Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12>>Cc1ccc(C(=O)Nc2c(C(O)(C(F)(F)F)C(F)(F)F)ccc3ccccc23)cc1 -US07125896B2,1,Brc1ccc(Br)nc1.OCCOCc1ccccc1>>Brc1ccc(OCCOCc2ccccc2)nc1 -US20090298832A1,2,COc1ccc(-c2nc(N)sc2Cc2ccccc2)cc1.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)Nc2nc(-c3ccc(OC)cc3)c(Cc3ccccc3)s2)cc1 -US08575204B2,2,Cc1ccc(N)cc1I.O=C(O)c1ccoc1>>Cc1ccc(NC(=O)c2ccoc2)cc1I -US06528504B2,7,O=C(O[C@H]1CCN(CCc2ccc(Cl)cc2)C1)c1ccc([N+](=O)[O-])cc1>>O[C@H]1CCN(CCc2ccc(Cl)cc2)C1 -US08609669B2,6,CCOC(=O)CSC1CCCC1>>O=C(O)CSC1CCCC1 -US08546408B2,1,COCCl.CON(C)C(=O)c1ncc(C)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>COCN(c1cc(C)cnc1C(=O)N(C)OC)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20110105571A1,2,CC(C)(C)OC(=O)N(CCc1ccc(Oc2ccc(N)cc2)cc1)Cc1ccccc1.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N(CCc1ccc(Oc2ccc(NC(=O)c3ccccc3)cc2)cc1)Cc1ccccc1 -US20030069224A1,6,COc1ccc(F)c(C=O)c1OC>>COc1ccc(F)c(C=O)c1O -US20100311732A1,7,CC(C)(C)OC(=O)N(CC(=O)O)Cc1ccc(F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N(CC(=O)O)Cc1ccc(F)cc1N -US20090325930A1,6,CCN(Cc1ccc(OCCN2CCCC2)cc1)c1ccccc1C1CCc2cc(OC)ccc2C1>>CCN(Cc1ccc(OCCN2CCCC2)cc1)c1ccccc1C1CCc2cc(O)ccc2C1 -US20120270838A1,1,BrCc1ccccc1.O=C(O)C1CCC(CO)CC1>>O=C(OCc1ccccc1)C1CCC(CO)CC1 -US05593993,2,COC(=O)C(Cc1ccccc1)NC(=S)Nc1nc(C)cs1>>Cc1csc(N2C(=O)C(Cc3ccccc3)NC2=S)n1 -US07897789B2,1,CC(C)(C)C(=O)CBr.CCC(CC)(c1ccc(O)c(C)c1)c1cc2cc(OC)ccc2s1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2cc(OC)ccc2s1 -US07872028B2,7,CC(C)(C)OC(=O)N1CCO[C@@H](C(=O)c2cccc(Cl)c2)C1>>CC(C)(C)OC(=O)N1CCO[C@@H]([C@@H](O)c2cccc(Cl)c2)C1 -US20130011361A1,6,COC(=O)c1cc(-n2cnn(Cc3ccc(F)cc3)c2=O)nn1Cc1ccc(OC)cc1>>COc1ccc(Cn2nc(-n3cnn(Cc4ccc(F)cc4)c3=O)cc2C(=O)O)cc1 -US07608618B2,7,COc1cc(CN(C)Cc2ccccc2)ccc1[N+](=O)[O-]>>COc1cc(CN(C)Cc2ccccc2)ccc1N -US20070185175A1,7,CCSc1cc(-c2cn(C)nc2-c2ccccc2F)ccc1[N+](=O)[O-]>>CCSc1cc(-c2cn(C)nc2-c2ccccc2F)ccc1N -US20100016366A1,2,NCCCCCCCCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1.O=C(O)Cc1ccc(O)c(F)c1>>O=C(Cc1ccc(O)c(F)c1)NCCCCCCCCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1 -US06900210B2,1,Brc1cccnc1.C[C@H](NC(=O)OC(C)(C)C)c1cccc(O)c1>>C[C@H](NC(=O)OC(C)(C)C)c1cccc(Oc2cccnc2)c1 -US20070259871A1,6,COCCOCCOc1cccc2c1CN(Cc1ccc(OC)cc1)C2>>COCCOCCOc1cccc2c1CNC2 -US20120029190A1,4,CC1C=CCN(C(=O)OCc2ccccc2)C1.O=C(OO)c1cccc(Cl)c1>>CC1CN(C(=O)OCc2ccccc2)CC2OC12 -US05672615,2,CCCCCCOc1ccc(S(=O)(=O)N(CC(=O)OCC)CC(C)C)cc1.NO>>CCCCCCOc1ccc(S(=O)(=O)N(CC(=O)NO)CC(C)C)cc1 -US20090181942A1,6,CCOC(=O)CC1CCN(C(=O)C(C)(C)[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)CC1>>COc1cccc([C@H]2O[C@H](C(C)(C)C(=O)N3CCC(CC(=O)O)CC3)c3cccn3-c3ccc(Cl)cc32)c1OC -US20110135671A1,1,CCCCNc1nc(N)c2nc(OC)n(CCCCl)c2n1.CCCN1CCNCC1>>CCCCNc1nc(N)c2nc(OC)n(CCCN3CCN(CCC)CC3)c2n1 -US05612354,7,O=C1CCc2cc(C(=O)c3ccccc3)ccc2N1>>O=C1CCc2cc(C(O)c3ccccc3)ccc2N1 -US08329729B2,2,Nc1ccc(Cl)cn1.O=C(Cl)CCl>>O=C(CCl)Nc1ccc(Cl)cn1 -US07592363B2,3,C#C[Si](C)(C)C.Fc1cc(F)c(Cn2nc3c(C(F)(F)F)cccc3c2-c2cccc(Br)c2)c(F)c1>>C[Si](C)(C)C#Cc1cccc(-c2c3cccc(C(F)(F)F)c3nn2Cc2c(F)cc(F)cc2F)c1 -US20110118230A1,1,Brc1ccc(CC2CCNCC2)cc1.C=O>>CN1CCC(Cc2ccc(Br)cc2)CC1 -US20050090559A1,1,COc1ccc(F)cc1C(C)(C)CC(O)(C=O)C(F)(F)F.Cc1ncc2c(N)cccc2n1>>COc1ccc(F)cc1C(C)(C)CC(O)(C=Nc1cccc2nc(C)ncc12)C(F)(F)F -US05705498,2,NCC1CCN(Cc2ccccc2)CC1.O=C(O)c1c[nH]c2ccccc12>>O=C(NCC1CCN(Cc2ccccc2)CC1)c1c[nH]c2ccccc12 -US08003649B2,1,CC(C)(C)c1ccc(C=O)cc1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>CC(C)(C)c1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US04017621,1,CC(C)N1CCOC(CCl)C1.c1ccc2c(c1)CCc1ccccc1N2>>CC(C)N1CCOC(CN2c3ccccc3CCc3ccccc32)C1 -US20050159598A1,6,Cc1cc(SCc2sc(-c3ccc(C(F)(F)F)cc3F)nc2C)ccc1O[Si](C)(C)C(C)(C)C>>Cc1cc(SCc2sc(-c3ccc(C(F)(F)F)cc3F)nc2C)ccc1O -US20150133426A1,2,CC(C)N.CCOC(=O)C1CCc2[nH]c3ncnc(Cl)c3c2C1>>CC(C)NC(=O)C1CCc2[nH]c3ncnc(Cl)c3c2C1 -US06881754B2,6,CC(C)(C)OC(=O)NCCc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>NCCc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 -US06380189B1,2,Nc1ccc(I)cc1C(=O)O.O=C=Nc1c(Cl)cccc1Cl>>O=C(Nc1ccc(I)cc1C(=O)O)Nc1c(Cl)cccc1Cl -US20120029023A1,3,BrCc1ccccc1.Brc1ccc(C2OCCO2)cn1>>c1ccc(Cc2ccc(C3OCCO3)cn2)cc1 -US20150094328A1,9,[N-]=[N+]=N[C@@H]1CCC(F)(F)C[C@H]1O>>N[C@@H]1CCC(F)(F)C[C@H]1O -US05885990,1,COC(=O)Cc1c(O)ccc2cc(C(=N)N)ccc12.NN=CNc1ccc(C(=O)O)cc1>>COC(=O)Cc1c(OC(=O)c2ccc(NC=NN)cc2)ccc2cc(C(=N)N)ccc12 -US20020156311A1,1,CCOC(=O)CO.Cc1c(N(Cc2ccc(Oc3ccc(F)c(O)c3)cc2)Cc2ccc(F)cc2F)cccc1[N+](=O)[O-]>>CCOC(=O)COc1cc(Oc2ccc(CN(Cc3ccc(F)cc3F)c3cccc([N+](=O)[O-])c3C)cc2)ccc1F -US06642381B2,1,BrCc1cccc(Br)c1.Nc1nc(N)c2nc(CN3CCNCC3)nnc2n1>>Nc1nc(N)c2nc(CN3CCN(Cc4cccc(Br)c4)CC3)nnc2n1 -US04145420,2,O=C=Nc1ccccc1.O=c1[nH]c2ccccc2c2cc(CO)nn12>>O=C(Nc1ccccc1)OCc1cc2c3ccccc3[nH]c(=O)n2n1 -US20060211678A1,6,COc1ccc([N+](=O)[O-])cc1-c1cncs1>>O=[N+]([O-])c1ccc(O)c(-c2cncs2)c1 -US20150065495A1,7,O=[N+]([O-])c1ccc2[nH]c(Cl)nc2c1>>Nc1ccc2[nH]c(Cl)nc2c1 -US20100280268A1,6,COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C#N)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc(Oc3ccc(NS(=O)(=O)c4ccc(C)cc4)c(C(=O)O)c3)cc2C#N)cc1 -US08252795B2,1,N#Cc1ccc(F)c([N+](=O)[O-])c1.OCCN1CCOCC1>>N#Cc1ccc(OCCN2CCOCC2)c([N+](=O)[O-])c1 -US05556861,1,CN(C)C1(C)CNC1.O=C(O)c1cn(C2CC2)c2nc3cc(F)c(F)cc3cc2c1=O>>CN(C)C1(C)CN(c2cc3nc4c(cc3cc2F)c(=O)c(C(=O)O)cn4C2CC2)C1 -US04746602,7,O=c1cccc2c(O)c([N+](=O)[O-])ccc2n1>>Nc1ccc2nc(=O)cccc2c1O -US08501755B2,1,CNC.O=C(C=CCBr)N1CCc2c(sc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1>>CN(C)C/C=C/C(=O)N1CCc2c(sc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1 -US05935970,6,C[C@@H]1CN(Cc2ccccc2)CCN1C(=O)OC(C)(C)C>>C[C@@H]1CNCCN1C(=O)OC(C)(C)C -US20100130492A1,2,C[C@H](O)C(=O)O.C[C@H]1CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC2CC2)CCN1>>C[C@H](O)C(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC2CC2)C[C@@H]1C -US20120289505A1,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(Oc5ccccc5)cc4)cc3)cc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(Oc5ccccc5)cc4)cc3)cc2C1=O -US09049878B2,2,CCOC(=O)c1c(C)nc2cccc(OC[C@H](C)N)c2c1N.COc1cc(C(=O)O)ccc1OCCO>>CCOC(=O)c1c(C)nc2cccc(OC[C@H](C)NC(=O)c3ccc(OCCO)c(OC)c3)c2c1N -US08058269B2,2,CC(=O)N1CCNCC1.O=C(O)CN(C1CCCCC1)C1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc21>>CC(=O)N1CCN(C(=O)CN(C2CCCCC2)C2(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc32)CC1 -US20090048258A1,7,COc1ccc(C(=O)CCC(=O)Nc2cc(-c3ccccc3)c(Cc3ccccc3)s2)cc1CCCOC(C)=O>>COc1ccc(C(=O)CCC(=O)Nc2cc(-c3ccccc3)c(Cc3ccccc3)s2)cc1CCCO -US20140179669A1,2,COc1cccc2c1C[C@H]1NCC[C@]2(C)C1(C)C.O=C(O)C1CCCC1>>COc1cccc2c1C[C@H]1N(C(=O)C3CCCC3)CC[C@]2(C)C1(C)C -US20120258948A1,6,C[C@@](CCn1ccc(/C=C/c2ccccc2)cc1=O)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>CC(CCn1ccc(/C=C/c2ccccc2)cc1=O)(C(=O)NO)S(C)(=O)=O -US20090042945A1,1,CC(C)(C)CNc1noc2ccc(-c3cccc(C=O)c3)cc12.NC1CC1>>CC(C)(C)CNc1noc2ccc(-c3cccc(CNC4CC4)c3)cc12 -US20080090806A1,1,Nc1ccncc1N.O=C1CCN(Cc2ccccc2)CC1>>Nc1ccncc1NC1CCN(Cc2ccccc2)CC1 -US20060160794A1,1,CI.Cc1ccc(N)c(Cl)c1>>CNc1ccc(C)cc1Cl -US20080064740A1,2,Cc1cc(CN)ccc1O.Cc1sc(C(=O)O)c2c1[C@H]1[C@@H](C2)C1(C)C>>Cc1cc(CNC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)ccc1O -US20100261710A1,2,CC(C)(C)OC(=O)N1CCC(CCC(=O)O)CC1.CNOC>>CON(C)C(=O)CCC1CCN(C(=O)OC(C)(C)C)CC1 -US07825238B2,2,CCCCCCCCCCCCCCCCCC(=O)OCC(COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)CC(=O)O.Nc1nc2c(ncn2[C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]1>>CCCCCCCCCCCCCCCCCC(=O)OCC(COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)CC(=O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@@H]1F -US05789423,6,CC(C)Oc1ccc(C(C)(C)C#N)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1>>CC(C)Oc1ccc(C(C)(C)C#N)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 -US20150057265A1,2,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2N)C1.CC(C)(C)OC(=O)Nc1sc2cc(F)cnc2c1C(=O)O>>CC(C)(C)OC(=O)Nc1sc2cc(F)cnc2c1C(=O)Nc1cnccc1N1CCC[C@H](NC(=O)OC(C)(C)C)C1 -US20120016119A1,6,COC(=O)c1cnc(N2CCC(n3cc(F)c4c(Nc5ccc(C(=O)N(C)C)cc5F)ncnc43)CC2)nc1>>CN(C)C(=O)c1ccc(Nc2ncnc3c2c(F)cn3C2CCN(c3ncc(C(=O)O)cn3)CC2)c(F)c1 -US20090203697A1,7,CCOC(=O)[C@H]1CC[C@@H](c2ccc(F)c(F)c2)N1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1[C@H](CO)CC[C@@H]1c1ccc(F)c(F)c1 -US20040167123A1,6,O=c1c(C2=NS(=O)(=O)c3cc(OCc4ccccc4)ccc3N2)c(O)c2ccccc2n1NC1CCC1>>O=c1c(C2=NS(=O)(=O)c3cc(O)ccc3N2)c(O)c2ccccc2n1NC1CCC1 -US20050124605A1,1,COc1cc(CBr)cc(OC)c1.O=C1CN=C(c2ccccc2)c2ccccc2N1>>COc1cc(CN2C(=O)CN=C(c3ccccc3)c3ccccc32)cc(OC)c1 -US04692182,2,CC(=O)OC(C)=O.CC1(C)CON(Cc2cc(NN)ccc2Cl)C1=O>>CC(=O)NNc1ccc(Cl)c(CN2OCC(C)(C)C2=O)c1 -US20140171313A1,2,CON(CC(F)(F)F)C(=O)C1(N)CC1.O=C(O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1C(F)(F)F>>CON(CC(F)(F)F)C(=O)C1(NC(=O)c2ccc(/C=C/C(c3cc(Cl)c(Cl)c(Cl)c3)C(F)(F)F)cc2C(F)(F)F)CC1 -US20150018547A1,6,COC(=O)Cc1csc2cc(OCc3cc(C(F)(F)F)nn3C)cc(C)c12>>Cc1cc(OCc2cc(C(F)(F)F)nn2C)cc2scc(CC(=O)O)c12 -US20050080260A1,3,BrCCOc1ccccc1.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)c2ccc(OCCBr)cc2)cc1 -US05270342,2,Cc1cc(N)cc(C)c1SC#N.Cc1ccccc1CC(=O)Cl>>Cc1ccccc1CC(=O)Nc1cc(C)c(SC#N)c(C)c1 -US20060217348A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCc1nn2c(-c3ccc(Cl)cc3Cl)cccc2c1N>>CCc1nn2c(-c3ccc(Cl)cc3Cl)cccc2c1NC(=O)OC(C)(C)C -US20070073064A1,2,NCC(=O)N[C@@H]1CCN(Cc2c[nH]c3ccccc23)C1.Nc1ccc(OC(F)(F)F)cc1C(=O)O>>Nc1ccc(OC(F)(F)F)cc1C(=O)NCC(=O)N[C@@H]1CCN(Cc2c[nH]c3ccccc23)C1 -US20060089367A1,2,CCCCC(=O)Cl.Fc1cc2nc(COc3ccccc3)n(Cc3ccc(OC(F)(F)F)cc3)c2cc1N1CCNCC1>>CCCCC(=O)N1CCN(c2cc3c(cc2F)nc(COc2ccccc2)n3Cc2ccc(OC(F)(F)F)cc2)CC1 -US20130123537A1,2,N[C@H](CO)C(=O)O.O=C(Cl)OCc1ccccc1>>O=C(N[C@H](CO)C(=O)O)OCc1ccccc1 -US08263656B2,1,CC(C)(C)OC(=O)CBr.O=C1CCCc2c(O)cc(Br)cc21>>CC(C)(C)OC(=O)COc1cc(Br)cc2c1CCCC2=O -US20070275956A1,1,CCOC(=O)CN(Cc1ccccc1)Cc1cccc(O)c1.CS(=O)(=O)OCCn1ccc2ccccc21>>CCOC(=O)CN(Cc1ccccc1)Cc1cccc(OCCn2ccc3ccccc32)c1 -US05412097,9,CCc1nc2c(C)cc(Br)nc2n1Cc1ccccc1.N#C[Cu]>>CCc1nc2c(C)cc(C#N)nc2n1Cc1ccccc1 -US09120749B2,1,CC(=O)c1cnc2ccc(Br)cc2c1Cl.CN1CCN(Cc2ccc(N)cc2)CC1>>CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(CN2CCN(C)CC2)cc1 -US07135475B2,2,CNc1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1.Cc1nn(C)c(Cl)c1C(=O)O>>Cc1nn(C)c(Cl)c1C(=O)N(C)c1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1 -US06784137B2,3,COC(=O)c1nc(Cl)cc(N)c1Cl.Cc1ccc(B(O)O)cc1C>>COC(=O)c1nc(-c2ccc(C)c(C)c2)cc(N)c1Cl -US20030191110A1,2,Fc1ccc(CN2CCNCC2)cc1.O=C(O)[C@@H]1CCCN1Cc1ccccc1>>O=C([C@@H]1CCCN1Cc1ccccc1)N1CCN(Cc2ccc(F)cc2)CC1 -US20040014802A1,6,CCCC(=O)Nc1n[nH]c2cc(-c3cccc(OCc4ccccc4)c3)ccc12>>CCCC(=O)Nc1n[nH]c2cc(-c3cccc(O)c3)ccc12 -US20140031345A1,3,O=c1[nH]c(=O)c2c(Br)cccc2[nH]1.OB(O)c1ccccc1>>O=c1[nH]c(=O)c2c(-c3ccccc3)cccc2[nH]1 -US20100093713A1,2,CN1CC(C)(C)OCC1C(=O)O.Nc1cc(Cl)cc2c1[nH]c1cnccc12>>CN1CC(C)(C)OCC1C(=O)Nc1cc(Cl)cc2c1[nH]c1cnccc12 -US06235731B1,1,BrCCCc1ccccc1.C1=C(/C=C/SCC2CCNCC2)Sc2cccc3ncc1n23>>C1=C(/C=C/SCC2CCN(CCCc3ccccc3)CC2)Sc2cccc3ncc1n23 -US08278442B2,1,N#Cc1ccc(Cl)nc1.OCc1cccc2c(O)cccc12>>N#Cc1ccc(Oc2cccc3c(CO)cccc23)nc1 -US20110201592A1,6,CC(C)(C)OC(=O)N1CC[C@H](Nc2nc(-c3ccccc3O)nc3ccc(C#CCO)cc23)C1>>OCC#Cc1ccc2nc(-c3ccccc3O)nc(N[C@H]3CCNC3)c2c1 -US05624950,3,COc1ccccc1Br.COc1ccccc1CC(=O)N1CC2C(=O)CCC(C)(c3ccccc3)C2C1>>COc1ccccc1CC(=O)N1CC2C(C1)C(O)(c1ccccc1OC)CCC2(C)c1ccccc1 -US20140171315A1,1,Nc1ccccn1.O=Cc1ccc(CBr)c(Cl)c1>>O=Cc1ccc(CNc2ccccn2)c(Cl)c1 -US20120035164A1,3,CCCOCCCNCc1ccc(B(O)O)s1.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1>>CCCOCCCNCc1ccc(-c2cc(C(N)=O)c3[nH]cc(C4CCN(S(=O)(=O)CC)CC4)c3c2)s1 -US08993555B2,6,COC(=O)c1cccc(-c2ccccn2)c1>>O=C(O)c1cccc(-c2ccccn2)c1 -US07252925B2,1,COCCOCCCl.Cc1nc2ccccc2[nH]1>>COCCOCCn1c(C)nc2ccccc21 -US04748183,2,CC(C)Oc1c(Br)c(Br)n(C)c1C(=O)O.Nc1nnn[nH]1>>CC(C)Oc1c(Br)c(Br)n(C)c1C(=O)Nc1nnn[nH]1 -US20110059948A1,1,Clc1nc2ccc(Br)cc2cc1Cc1ccccc1.c1c[nH]cn1>>Brc1ccc2nc(-n3ccnc3)c(Cc3ccccc3)cc2c1 -US20150246922A1,3,Cc1c2n(c3c(Br)cc(Cl)cc13)CCNC2=O.N#Cc1ccc(B(O)O)cc1>>Cc1c2n(c3c(-c4ccc(C#N)cc4)cc(Cl)cc13)CCNC2=O -US20090318690A1,1,CCCOc1ccc2c(CCC3CCNCC3)noc2c1CN(C)C.O=Cc1ccccc1>>CCCOc1ccc2c(CCC3CCN(Cc4ccccc4)CC3)noc2c1CN(C)C -US08063058B2,7,O=[N+]([O-])c1cnn(-c2ccccc2)c1>>Nc1cnn(-c2ccccc2)c1 -US20030216586A1,5,CC(C)(C)c1cc(Br)c(O)c(C(C)(C)C)c1.COCCl>>COCOc1c(Br)cc(C(C)(C)C)cc1C(C)(C)C -US20050256180A1,9,NC(=O)c1nn(-c2ccc(Br)cc2)c2c1CCc1ccc(NC(=O)c3ccccc3Cl)cc1-2.[C-]#N>>N#Cc1ccc(-n2nc(C(N)=O)c3c2-c2cc(NC(=O)c4ccccc4Cl)ccc2CC3)cc1 -US20110263594A1,7,O=[N+]([O-])c1ccc(Sc2nnc3ccccn23)cc1>>Nc1ccc(Sc2nnc3ccccn23)cc1 -US07786113B2,4,Cc1cc(C(=O)O)ccn1.Nc1cc(Br)cnc1N>>Cc1cc(-c2nc3cc(Br)cnc3[nH]2)ccn1 -US08486967B2,3,Nc1ccc(Br)cn1.OB(O)C1CC1>>Nc1ccc(C2CC2)cn1 -US08722711B2,6,CC(=O)O[C@@H](C)c1nc(-c2ccc(C(=O)OC(C)(C)C)c(F)c2)no1>>C[C@H](O)c1nc(-c2ccc(C(=O)OC(C)(C)C)c(F)c2)no1 -US20090099205A1,1,CC(CCNC(=O)OC(C)(C)C)N1CCC(=O)CC1.N#Cc1cccc(CN)n1>>CC(CCNC(=O)OC(C)(C)C)N1CCC(NCc2cccc(C#N)n2)CC1 -US08629157B2,1,CC(C)(C)c1csc(NC(=O)[C@@H]2CCCN2)n1.O=CC1CCOCC1>>CC(C)(C)c1csc(NC(=O)[C@@H]2CCCN2CC2CCOCC2)n1 -US07514449B2,1,CC(C)(C)OC(=O)NCCC=O.CN[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cn3)oc3cccnc23)CC1>>CN(CCCNC(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cn3)oc3cccnc23)CC1 -US20150087845A1,6,COc1c(NN=C2C(=O)N(c3ccc(C)c(C)c3)N=C2C)cccc1-c1cccc(C(=O)O)c1>>CC1=NN(c2ccc(C)c(C)c2)C(=O)C1=NNc1cccc(-c2cccc(C(=O)O)c2)c1O -US04357279,1,C[C@]12CC=C3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CCC2=C(Cl)C(Cl)S(=O)c1ccccc1.C[O-]>>COC(=C1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3=CC[C@]12C)C(Cl)S(=O)c1ccccc1 -US05036077,1,ClCC1CO1.Oc1ccc(Cl)cc1Cl>>Clc1ccc(OCC2CO2)c(Cl)c1 -US05773612,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CCO)CC1 -US20090227555A2,1,COC(=O)C1CCNCC1.Clc1cccc(Cl)n1>>COC(=O)C1CCN(c2cccc(Cl)n2)CC1 -US08119663B2,6,COC(=O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CCC(O)CC2)C1>>O=C(O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CCC(O)CC2)C1 -US07078425B2,2,COc1ccc(CC(N)C(=O)NCCCCc2ccccc2)c2ccn(S(=O)(=O)c3ccccc3)c12.O=S(=O)(Cl)c1ccccc1>>COc1ccc(CC(NS(=O)(=O)c2ccccc2)C(=O)NCCCCc2ccccc2)c2ccn(S(=O)(=O)c3ccccc3)c12 -US08618150B2,6,CC(C)(C)OC(=O)N(c1nc2ccccn2c1C1CC1)S(=O)(=O)c1ccccc1>>O=S(=O)(Nc1nc2ccccn2c1C1CC1)c1ccccc1 -US20030232820A1,1,BrCc1ccccc1.C[C@H](O)C(=O)O>>C[C@H](O)C(=O)OCc1ccccc1 -US20130085123A1,6,COc1ccc(Cn2c(=O)n(C)c(=O)c3cn(Cc4ccc(-n5cccn5)cc4)nc32)cc1>>Cn1c(=O)[nH]c2nn(Cc3ccc(-n4cccn4)cc3)cc2c1=O -US20080161341A1,8,CC(C)C(O)c1cc(Br)ccc1O>>CC(C)C(=O)c1cc(Br)ccc1O -US08829245B2,1,CC1(C)CC(=O)CC(C)(C#N)C1.N>>CC1(C)CC(N)CC(C)(C#N)C1 -US05811512,5,NCCCCCO.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCCCCO)C(F)(F)F -US03978127,7,O=C(O)c1ccccc1C(F)(F)C(F)(F)c1ccccc1>>OCc1ccccc1C(F)(F)C(F)(F)c1ccccc1 -US20100120798A1,7,N#CC1(C(=O)NCc2ccc(Cl)nc2)CCN(c2ncnc3[nH]ccc23)CC1>>NCC1(C(=O)NCc2ccc(Cl)nc2)CCN(c2ncnc3[nH]ccc23)CC1 -US20140228387A1,1,COCCS(=O)(=O)Cc1cccc(N)c1.Fc1ccc(-c2nc(Cl)ncc2F)c(OCc2ccccc2)c1>>COCCS(=O)(=O)Cc1cccc(Nc2ncc(F)c(-c3ccc(F)cc3OCc3ccccc3)n2)c1 -US20060079567A1,6,c1ccc(CN2CCC3Cc4sccc4C3C2)cc1>>c1cc2c(s1)CC1CCNCC21 -US20130338081A1,2,COC(=O)[C@@H]1C[C@H](N)CN1C(=O)OCc1ccccc1.C[C@@H](C(=O)N[C@H](C(=O)N1Cc2cc(C(=O)O)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C)N(C)C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@H](NC(=O)c2ccc3c(c2)CN(C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)C)[C@H](C(=O)N[C@@H]2CCCc4ccccc42)C3)CN1C(=O)OCc1ccccc1 -US06239131B1,6,Cc1ccc2c(c1)N(CC(=O)C(C)(C)C)C(=O)C(NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)CN2c1ccccc1>>Cc1ccc2c(c1)N(CC(=O)C(C)(C)C)C(=O)C(NC(=O)[C@@H](N)Cc1ccccc1)CN2c1ccccc1 -US07468391B2,6,COC(=O)C(C)(C)c1ccc(C#Cc2cc(OC)c3c(c2)C(C)(C)CCC3N(C)C2CC2)cc1>>COc1cc(C#Cc2ccc(C(C)(C)C(=O)O)cc2)cc2c1C(N(C)C1CC1)CCC2(C)C -US20150148344A1,3,Cc1noc(C)c1B1OC(C)(C)C(C)(C)O1.O=S(=O)(NC1CCCC1)c1cc(Cl)cc2nccnc12>>Cc1noc(C)c1-c1cc(S(=O)(=O)NC2CCCC2)c2nccnc2c1 -US20080269220A1,1,CCOC(=O)CCc1ccc(N)cc1F.CCOCCOc1cc(C)c(-c2cccc(C=O)c2)c(C)c1>>CCOCCOc1cc(C)c(-c2cccc(CNc3ccc(CCC(=O)OCC)c(F)c3)c2)c(C)c1 -US20110130380A1,1,C[C@@H](N)C1CCOCC1.Fc1cccc(Br)n1>>C[C@@H](Nc1cccc(Br)n1)C1CCOCC1 -US20140357614A1,6,CN(C(=O)OC(C)(C)C)[C@@H]1CCN(c2cnnc(NC34CC5CC(CC(C5)C3)C4)c2)C1>>CN[C@@H]1CCN(c2cnnc(NC34CC5CC(CC(C5)C3)C4)c2)C1 -US06617339B1,2,O=C(Cl)CCl.O=C1O[C@@H](COc2ccon2)CN1c1ccc(N2CCNCC2)c(F)c1>>O=C(CCl)N1CCN(c2ccc(N3C[C@H](COc4ccon4)OC3=O)cc2F)CC1 -US20070249670A1,7,COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1[N+](=O)[O-])C1CCCC1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1N)C1CCCC1 -US07375226B2,1,CCOC(=O)c1cc2cc(OC(F)(F)F)ccc2[nH]1.N#CCCl>>CCOC(=O)c1cc2cc(OC(F)(F)F)ccc2n1CC#N -US07772183B2,2,CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(O)CN2C1=O.O=C(Cl)c1ccc2ccccc2c1>>CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(OC(=O)c3ccc4ccccc4c3)CN2C1=O -US20060234927A1,6,C#CCN1CCN(C(=O)OC(C)(C)C)CC1>>C#CCN1CCNCC1 -US07750186B2,6,CC(=O)Nc1ccc(F)cc1-c1ccc(Cl)c(Cl)c1>>Nc1ccc(F)cc1-c1ccc(Cl)c(Cl)c1 -US20120015991A1,3,CC(=O)Cl.CCOC(=O)C1(c2ccc(-c3ccccc3)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(C(C)=O)cc3)cc2)CC1 -US20110077234A1,6,CCOC(=O)CSc1cnc(NC(=O)N(CC2CCCC2)c2ccc(F)c(F)c2F)s1>>O=C(O)CSc1cnc(NC(=O)N(CC2CCCC2)c2ccc(F)c(F)c2F)s1 -US20130178461A1,6,CC(=O)OCc1c(-c2cc(Nc3ccc(OC(C)(C)CN(C)C)cn3)c(=O)n(C)n2)cccc1-n1ncc2cc(C(C)(C)C)cc(F)c2c1=O>>CN(C)CC(C)(C)Oc1ccc(Nc2cc(-c3cccc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3CO)nn(C)c2=O)nc1 -US20050119225A1,7,COc1ccc(N(Cc2cccnc2)c2ccc([N+](=O)[O-])c(C(=O)O)c2)cc1OC1CCCC1>>COc1ccc(N(Cc2cccnc2)c2ccc(N)c(C(=O)O)c2)cc1OC1CCCC1 -US20070203080A1,3,CCc1c(OC)cc(C)cc1OC.CN(C)C=O>>CCc1c(OC)cc(C)c(C=O)c1OC -US20040224997A1,3,CCOC(=O)C(CCc1ccccc1)CC(=O)c1ccc(Br)cc1.O=[N+]([O-])c1ccc(B(O)O)cc1>>CCOC(=O)C(CCc1ccccc1)CC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1 -US07608618B2,9,Nc1ncc(-c2ccccc2)nc1Br>>Nc1cnc(-c2ccccc2)cn1 -US07186734B2,1,CCCCn1c(-c2ccccc2)nc(F)c1CO.NCc1ccc2c(c1)OCO2>>CCCCn1c(-c2ccccc2)nc(F)c1CNCc1ccc2c(c1)OCO2 -US08263606B2,1,CC(C)c1nc(CCl)cs1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCO3>>CC(C)c1nc(CN2C(=O)C3(COc4cc5c(cc43)OCCO5)c3ccccc32)cs1 -US20100105727A1,2,CC(=O)N1CCC(CO)CC1.CS(=O)(=O)Cl>>CC(=O)N1CCC(COS(C)(=O)=O)CC1 -US20130196974A1,9,COC(=O)c1ccc2nc(N3CCSc4ccccc4C3)cc(Cl)c2c1.N>>NC(=O)c1ccc2nc(N3CCSc4ccccc4C3)cc(Cl)c2c1 -US07968554B2,1,Cc1ccc(NC(=O)c2ccc(NCCO)c(Cl)c2)cc1O.Cn1nc(CBr)c2c(Cl)ncnc21>>Cc1ccc(NC(=O)c2ccc(NCCO)c(Cl)c2)cc1OCc1nn(C)c2ncnc(Cl)c12 -US20130237535A1,3,CC1(C)OB(c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)OC1(C)C.Fc1cnc2cc(Br)ccc2c1>>O=C1COC2(CCN(S(=O)(=O)c3ccc(-c4ccc5cc(F)cnc5c4)cc3)CC2)CN1C1CC1 -US06403610B1,5,C=C[C@H]1CNCC[C@H]1CCC(=O)c1ccnc2ccc(OC)cc12.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=C[C@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1CCC(=O)c1ccnc2ccc(OC)cc12 -US08420666B2,6,CCn1ncc2c(NCc3ccccc3)c(C3=NOC4(CCC4)C3)cnc21>>CCn1ncc2c(N)c(C3=NOC4(CCC4)C3)cnc21 -US20110263611A1,2,CCOC(=O)C[S@@](=O)(=NC(=O)c1cncc(C#Cc2cccc(O)c2)c1)c1ccccc1.NCCO>>O=C(CS(=O)(=NC(=O)c1cncc(C#Cc2cccc(O)c2)c1)c1ccccc1)NCCO -US05360802,2,NS(=O)(=O)C(F)(F)F.O=C(Cl)c1cccc([N+](=O)[O-])c1>>O=C(NS(=O)(=O)C(F)(F)F)c1cccc([N+](=O)[O-])c1 -US20140371240A1,2,CCCC(=O)Cl.Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1C(=O)Nc1ccc(Cl)c(C[NH3+])c1>>CCCC(=O)NCc1cc(NC(=O)c2c(C(F)(F)F)c(C(F)(F)C(F)(F)F)nn2C)ccc1Cl -US07435744B2,2,Cc1ccc(OC2CCNCC2)cc1.O=C1COc2cc(NC(=O)C(=O)O)ccc2N1>>Cc1ccc(OC2CCN(C(=O)C(=O)Nc3ccc4c(c3)OCC(=O)N4)CC2)cc1 -US20070244125A1,1,Cc1ccc(B(O)O)cc1.O=C(c1ccc2[nH]c(C(=O)N3CCS(=O)(=O)CC3)cc2c1)N1CCN(C2CCCC2)CC1>>Cc1ccc(-n2c(C(=O)N3CCS(=O)(=O)CC3)cc3cc(C(=O)N4CCN(C5CCCC5)CC4)ccc32)cc1 -US08097759B2,2,Cc1ccc(N)cc1C(F)(F)F.O=C(O)c1cc(Cl)ccc1O>>Cc1ccc(NC(=O)c2cc(Cl)ccc2O)cc1C(F)(F)F -US20100179216A1,7,Cc1ccc(C#CCO)cc1Cl>>Cc1ccc(CCCO)cc1Cl -US04465850,2,CC1(C2CCCC2)Cc2cc(OCCCC(=O)O)c(Cl)c(Cl)c2C1=O.CCO>>CCOC(=O)CCCOc1cc2c(c(Cl)c1Cl)C(=O)C(C)(C1CCCC1)C2 -US20140088124A1,7,CCOC(=O)[C@@H]1CC[C@H](Oc2ccncc2)CC1>>CCOC(=O)[C@@H]1CC[C@H](OC2CCNCC2)CC1 -US08304434B2,3,CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1.C[Mg+]>>CC(=O)C1CCN(C(=O)OC(C)(C)C)CC1 -US20090131468A1,3,CC(C)OB(C#CC(C)(C)C)OC(C)C.NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)c(F)c1>>CC(C)(C)C#Cc1ccc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cc1F -US20090264650A1,7,COC(=O)C12CC3CC(C1)CC(N1CCCC1=O)(C3)C2>>O=C1CCCN1C12CC3CC(CC(CO)(C3)C1)C2 -US07582626B2,7,CCOC(=O)C1=C(NCCC(C)C)CCC1>>CCOC(=O)[C@@H]1CCC[C@@H]1NCCC(C)C -US07582626B2,7,CCOC(=O)C1=C(NCCC(C)C)CCC1>>CCOC(=O)[C@@H]1CCC[C@H]1NCCC(C)C -US20110263584A1,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccc(F)cc2)OC1=O.N#Cc1cnc(Cl)cn1>>C[C@@H](c1ccc(-c2cnc(C#N)cn2)cc1)N1CC[C@](CC(C)(C)O)(c2ccc(F)cc2)OC1=O -US20060211724A1,1,CCOCCC(=O)O.O=C1c2c(c(O)c3nccnc3c2O)C(=O)N1Cc1ccc(Cl)c(Cl)c1>>CCOCCC(=O)Oc1c2c(c(O)c3nccnc13)C(=O)N(Cc1ccc(Cl)c(Cl)c1)C2=O -US20070049618A1,2,NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O -US07598236B2,1,Cc1cc(Br)cnc1Cl.O=C(OCc1ccccc1)N1C[C@@H]2CN[C@@H]2C1>>Cc1cc(N2C[C@H]3CN(C(=O)OCc4ccccc4)C[C@H]32)cnc1Cl -US08367700B2,2,NCCc1ccc(F)cc1.O=C(O)c1ccccc1>>O=C(NCCc1ccc(F)cc1)c1ccccc1 -US07071175B1,9,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCC(CO)CC1>>CC(C)(C)OC(=O)N1CCC(CBr)CC1 -US05212180,2,CC(=O)c1ccccc1CC[C@@H](O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1.CS(=O)(=O)Cl>>CC(=O)c1ccccc1CC[C@@H](OS(C)(=O)=O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 -US20100087446A1,4,CCOC(=O)C(C)(C)c1cc(Br)c(N)c(C#Cc2ccc(OC(F)(F)F)cc2)c1>>CCOC(=O)C(C)(C)c1cc(Br)c2[nH]c(-c3ccc(OC(F)(F)F)cc3)cc2c1 -US07943776B2,1,CCN(CC)CCO.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(OCc2cccc(CBr)n2)cc1>>CCN(CC)CCOCc1cccc(COc2ccc(C(=O)Nc3cc(C(=O)NC4CC4)ccc3C)cc2)n1 -US05731315,6,CC(C)(C)OC(=O)N[C@H]1CCN(Cc2cccc(C#N)c2)C1=O>>N#Cc1cccc(CN2CC[C@H](N)C2=O)c1 -US05185360,4,CC(C)c1ccc(NN)cc1.COc1c(C)cc2c(c1C)CCC2=O>>COc1c(C)cc2c(c1C)Cc1c-2[nH]c2ccc(C(C)C)cc12 -US07737166B2,4,CC(N)=S.Cc1c(C(=O)CBr)c(F)c2oc(C3CC3)nc2c1C#N>>Cc1nc(-c2c(C)c(C#N)c3nc(C4CC4)oc3c2F)cs1 -US03954753,2,C1CCNC1.COC(=O)c1nc(Cl)cnc1N>>Nc1ncc(Cl)nc1C(=O)N1CCCC1 -US06503903B1,2,CC(C)(C)OC(=O)c1ccc2c(c1)CN(Cc1ccccc1)C(=O)[C@@H](CO)N2.CNCc1cc2ccccc2n1C>>CN(Cc1cc2ccccc2n1C)C(=O)c1ccc2c(c1)CN(Cc1ccccc1)C(=O)[C@@H](CO)N2 -US20130237422A1,8,COC(=O)c1nc(-c2ccc(Cl)c(SC)c2F)nc(N)c1Cl.OO>>COC(=O)c1nc(-c2ccc(Cl)c(S(C)=O)c2F)nc(N)c1Cl -US08722662B2,6,CC(C)(C)OC(=O)N1CCO[C@@H]([C@@H](O)CO)[C@H](c2ccc(Cl)c(Cl)c2)C1>>OC[C@H](O)[C@@H]1OCCNC[C@H]1c1ccc(Cl)c(Cl)c1 -US08575360B2,2,C[C@@]1(Cc2ccc(C#N)cc2)C(=O)N(c2cc(Cl)c(F)c(Cl)c2)c2ncc(C(=O)Cl)n21.NC1(C(=O)NC2(c3ncc(I)cn3)CC2)CC1>>C[C@@]1(Cc2ccc(C#N)cc2)C(=O)N(c2cc(Cl)c(F)c(Cl)c2)c2ncc(C(=O)NC3(C(=O)NC4(c5ncc(I)cn5)CC4)CC3)n21 -US08247429B2,2,CCC(=O)OC(=O)CC.NCCC1CCc2ccn3nccc3c21>>CCC(=O)NCCC1CCc2ccn3nccc3c21 -US07989438B2,6,COCOc1cc(OC)ccc1-c1[nH]c2cc(C(=O)OC)ccc2c1C1CCCCC1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(OC)cc3O)[nH]c2c1 -US05168110,1,CC(C)(CO)C(=O)O.ClCC1CO1>>CC(C)(CO)C(=O)OCC1CO1 -US20090069282A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.Clc1ccc(OCCN2CCCC2)nn1>>Clc1ccc(-c2ccc(C#Cc3ccc(OCCN4CCCC4)nn3)nc2)cc1 -US07202247B2,6,COC(=O)COc1c(OC)cc(C(=O)C#Cc2cc(-c3cccs3)c(OC)cc2OC)cc1OC>>COc1cc(OC)c(-c2cccs2)cc1C#CC(=O)c1cc(OC)c(OCC(=O)O)c(OC)c1 -US05434186,3,C#CCCCCOC1CCCCO1.COC(=O)/C=C/c1c(OCCCCC(=O)OC)cccc1OS(=O)(=O)C(F)(F)F>>COC(=O)/C=C/c1c(C#CCCCCOC2CCCCO2)cccc1OCCCCC(=O)OC -US20140349993A1,1,C1COCCN1.Nc1ncc(Br)s1>>Nc1ncc(N2CCOCC2)s1 -US20110166146A1,1,Cc1cc(C)nc(N)n1.Cc1ccc(-c2nc3c(Cl)cc(Cl)cn3c2CCl)cc1>>Cc1ccc(-c2nc3c(Cl)cc(Cl)cn3c2CNc2nc(C)cc(C)n2)cc1 -US20130281490A1,7,O=C(O)c1ccc(-c2ccsc2)cc1>>OCc1ccc(-c2ccsc2)cc1 -US20070254957A1,6,C=C(C)CC(C(=O)OC)c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1>>C=C(C)CC(C(=O)OC)c1cc(O)cc(OCc2ccccc2)c1 -US20100210641A1,1,C1=C(c2ccn3c(-c4ccnc(-c5ccccc5)c4)cnc3c2)CCNC1.CC(C)=O>>CC(C)N1CC=C(c2ccn3c(-c4ccnc(-c5ccccc5)c4)cnc3c2)CC1 -US20120309812A1,2,Nc1c(Cl)cc(C(=O)C(F)(F)F)cc1Cl.O=C(O)c1cccc([N+](=O)[O-])c1F>>O=C(Nc1c(Cl)cc(C(=O)C(F)(F)F)cc1Cl)c1cccc([N+](=O)[O-])c1F -US07998988B2,1,Clc1ccccc1CBr.OCc1ccccc1O>>OCc1ccccc1OCc1ccccc1Cl -US20050239857A1,1,CC(C)c1c(C=O)nc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O1.N>>CC(C)c1c(CN)nc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O1 -US20030171396A1,1,CC=O.CCCCCS(=O)(=O)NC(=O)c1ccc2nc(C)n(Cc3ccc(NC)cc3Cl)c2n1>>CCCCCS(=O)(=O)NC(=O)c1ccc2nc(C)n(Cc3ccc(N(C)CC)cc3Cl)c2n1 -US20040209897A1,1,CCOC(=O)CCCBr.Oc1cccc(Br)c1>>CCOC(=O)CCCOc1cccc(Br)c1 -US08563570B2,1,O=C1N([C@@H]2CC[C@H](O)CC2)CC[C@]12CCCN(c1ncc(Br)cn1)C2.c1cn[nH]c1>>O=C1N([C@@H]2CC[C@H](O)CC2)CC[C@]12CCCN(c1ncc(-n3cccn3)cn1)C2 -US20070249607A1,3,CC(C)(C)OC(=O)N1CCC(COCc2cc(N)cc(Br)c2)(c2ccccc2)CC1.N#Cc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)N1CCC(COCc2cc(N)cc(-c3ccc(C#N)cc3)c2)(c2ccccc2)CC1 -US08022062B2,1,CC(N)c1ccc(F)c(Cl)c1.O=C(N1CCc2ccc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F>>CC(Nc1c(Cl)ccc2c1CCN(C(=O)C(F)(F)F)CC2)c1ccc(F)c(Cl)c1 -US05108486,3,CC(=O)c1cccc(-n2c(C(F)(F)F)nn(C)c2=S)c1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(C)c1cccc(-n2c(C(F)(F)F)nn(C)c2=S)c1 -US05935990,8,NS(=O)(=O)c1ccc(CO)cc1>>NS(=O)(=O)c1ccc(C=O)cc1 -US20100105659A1,3,CC(C)(C)OC(=O)N1CCC(c2nsc(Nc3ncc(Oc4ccc(Br)cc4)cc3Sc3ccccc3Cl)n2)CC1.CN(C)C=O>>CC(C)(C)OC(=O)N1CCC(c2nsc(Nc3ncc(Oc4ccc(C=O)cc4)cc3Sc3ccccc3Cl)n2)CC1 -US04753941,2,Nc1ccc2ccc(Cl)nc2n1.O=C(O)C1=CSCS1>>O=C(Nc1ccc2ccc(Cl)nc2n1)C1=CSCS1 -US09023844B2,1,CC(=O)COS(C)(=O)=O.Oc1cc(-c2ccc(F)cc2)n[nH]1>>CC(=O)COc1cc(-c2ccc(F)cc2)n[nH]1 -US20090062536A1,2,COc1nc(Cc2cccc(Br)c2N)nc(OC)n1.O=S(=O)(Cl)C(F)F>>COc1nc(Cc2cccc(Br)c2NS(=O)(=O)C(F)F)nc(OC)n1 -US07524841B2,1,CC(C)(C)OC(=O)N1CCC(F)(CO)CC1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCC(F)(CN2C(=O)c3ccccc3C2=O)CC1 -US07402596B2,7,O=c1c2cccc([N+](=O)[O-])c2ccn1Cc1ccccc1>>Nc1cccc2c(=O)n(Cc3ccccc3)ccc12 -US05464865,1,CCOC(=O)CCCCCBr.Oc1ccc2ccccc2c1>>CCOC(=O)CCCCCOc1ccc2ccccc2c1 -US06489344B1,6,CC(C)(C)OC(=O)N1CCN(c2cnc(NCCNc3ccc([N+](=O)[O-])cn3)nc2-c2ccc(Cl)cc2Cl)CC1>>O=[N+]([O-])c1ccc(NCCNc2ncc(N3CCNCC3)c(-c3ccc(Cl)cc3Cl)n2)nc1 -US20070276138A1,6,CCOC(=O)C(Cc1ccc(OCCCOc2ccc(Oc3ccccc3)cc2)c(C)c1)OC>>COC(Cc1ccc(OCCCOc2ccc(Oc3ccccc3)cc2)c(C)c1)C(=O)O -US20090286791A1,2,CC(C)(C)OC(=O)Nc1nn(-c2ccccc2)cc1C(=O)O.NCCNC(=O)c1ccc(OCC(F)(F)F)nc1>>CC(C)(C)OC(=O)Nc1nn(-c2ccccc2)cc1C(=O)NCCNC(=O)c1ccc(OCC(F)(F)F)nc1 -US20070003539A1,2,CC(C)S(=O)(=O)c1ccc(N)cc1C#N.CN(C)C(=O)Cl>>CC(C)S(=O)(=O)c1ccc(NC(=O)N(C)C)cc1C#N -US05252732,7,O=C(O)Cc1c[nH]c2ccc(Br)cc12>>OCCc1c[nH]c2ccc(Br)cc12 -US20070249670A1,2,COC(=O)c1cc(N)cc(C(=O)OC)c1.Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)O)c(C)c1>>COC(=O)c1cc(NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(C)cc(C)cc2C)cc(C(=O)OC)c1 -US20100197760A1,7,Clc1ccc(C2=CCNC2)cc1Cl>>Clc1ccc(C2CCNC2)cc1Cl -US20040006067A1,2,CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1.CS(=O)(=O)Nc1ccccc1C1CCN(C(=O)[C@H](N)Cc2ccc(Cl)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(CC(=O)N[C@H](Cc2ccc(Cl)cc2)C(=O)N2CCC(c3ccccc3NS(C)(=O)=O)CC2)CC1 -US20080200535A1,6,CC(C)(C)OC(=O)N[C@@H]1C=C[C@H](C(=O)O)C1>>N[C@@H]1C=C[C@H](C(=O)O)C1 -US20060252931A1,7,Cc1cc(CC(=O)C(=O)O)cc(Cl)c1OCc1ccccc1>>Cc1cc(C[C@@H](O)C(=O)O)cc(Cl)c1OCc1ccccc1 -US08426411B2,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(=O)O)C1.Cc1ccc(S(=O)(=O)n2ccc3nc(NN)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3nc(NNC(=O)[C@@H]4CC[C@@H](NC(=O)OC(C)(C)C)C4)cnc32)cc1 -US07405299B2,1,C1COCCN1.O=Cc1cnc2ccc(Br)cn12>>Brc1ccc2ncc(CN3CCOCC3)n2c1 -US20140057895A1,6,CC(C)c1nn(-c2ncc(C3CCN(C(=O)OCc4ccccc4)CC3)[nH]2)c2c(F)cccc12>>CC(C)c1nn(-c2ncc(C3CCNCC3)[nH]2)c2c(F)cccc12 -US20110053943A1,1,Brc1cnc(C2CCN(Cc3ccccc3)C2)nc1.CO>>COc1cnc(C2CCN(Cc3ccccc3)C2)nc1 -US20100331293A1,1,Cc1c(-c2ccc(N(C)C)nc2)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>Cc1c(-c2ccc(N(C)C)nc2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1 -US20130210769A1,1,N#Cc1ccccc1F.O=C1OC[C@H](c2cccc(O)c2)N1c1ccc(Cl)cc1>>N#Cc1ccccc1Oc1cccc([C@H]2COC(=O)N2c2ccc(Cl)cc2)c1 -US20140315949A1,7,CC(CC(=O)O)c1ccc(Br)cc1>>CC(CCO)c1ccc(Br)cc1 -US20090143367A1,7,Cc1nc(-c2ccccc2Cl)n2c1c(C)nc1cc(OCc3cccc([N+](=O)[O-])c3)ccc12>>Cc1nc(-c2ccccc2Cl)n2c1c(C)nc1cc(OCc3cccc(N)c3)ccc12 -US06683097B2,7,O=C(O)c1cn(-c2ccc(OC(F)(F)F)c(Cl)c2)cn1>>OCc1cn(-c2ccc(OC(F)(F)F)c(Cl)c2)cn1 -US08623859B2,1,COc1cc(C)c(S(=O)(=O)N(C)Cc2nnc(C(=O)N3CCNCC3)o2)c(C)c1.O=Cc1ccc(Cl)nc1>>COc1cc(C)c(S(=O)(=O)N(C)Cc2nnc(C(=O)N3CCN(Cc4ccc(Cl)nc4)CC3)o2)c(C)c1 -US20140303164A1,3,CC(C)(O)C#Cc1ccc(Br)c([C@H](Cc2cccc(F)c2)NC(=O)OC(C)(C)C)n1.Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(B3OC(C)(C)C(C)(C)O3)c21>>Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@H](Cc3cccc(F)c3)NC(=O)OC(C)(C)C)c21 -US20050038035A1,1,CC(C)(C)OC(=O)Nc1nc(CCN)cs1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)OC(=O)Nc1nc(CCNc2ccc([N+](=O)[O-])cc2)cs1 -US04720500,2,COc1cccc(-c2ccc3ccc(N)nc3n2)c1.O=C(O)c1cccc(Br)c1>>COc1cccc(-c2ccc3ccc(NC(=O)c4cccc(Br)c4)nc3n2)c1 -US09067898B1,3,CCOC(=O)CP(=O)(OCC)OCC.COc1ccc2c(c1)CCC2=O>>CCOC(=O)/C=C1\CCc2cc(OC)ccc21 -US20040220403A1,7,COC(=O)c1c(OC)ccc(-n2nnnc2C(F)(F)F)c1OC>>COc1ccc(-n2nnnc2C(F)(F)F)c(OC)c1CO -US07767671B2,2,CC(=O)Cl.Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(N4CCC(N5CCCC5)CC4)c(N)cc23)cc1Cl>>CC(=O)Nc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1N1CCC(N2CCCC2)CC1 -US08722659B2,1,COc1ccc(CNC(=O)c2cc(OCc3ccccc3)ccc2N)cc1OC.O=C1CCSCC1>>COc1ccc(CNC(=O)c2cc(OCc3ccccc3)ccc2NC2CCSCC2)cc1OC -US20060025445A1,2,CCCS(=O)(=O)Cl.CCNC(C)C(=O)c1ccccc1>>CCCS(=O)(=O)N(CC)C(C)C(=O)c1ccccc1 -US07015213B1,9,Nc1ccccc1C(F)(F)F.S=C(Cl)Cl>>FC(F)(F)c1ccccc1N=C=S -US20060074237A1,2,COCc1ccc(N)nc1C.Cc1c(Cl)cccc1S(=O)(=O)Cl>>COCc1ccc(NS(=O)(=O)c2cccc(Cl)c2C)nc1C -US04833160,1,CONC(=O)C(Br)CCBr>>CON1CCC(Br)C1=O -US20050267118A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1CCCN1>>CC(C)(C)OC(=O)N1CCCC1C(=O)O -US05081152,9,BrC(Br)(Br)Br.OCC#CCO>>OCC#CCBr -US20090156509A1,2,COC(=O)CCCCCN.O=C(O)c1ccccn1>>COC(=O)CCCCCNC(=O)c1ccccn1 -US08431596B2,3,COc1ccc(B(O)O)cc1.Nc1nc2cccc(Br)n2n1>>COc1ccc(-c2cccc3nc(N)nn23)cc1 -US20100137298A1,6,CCOC(=O)c1oc2cccc(C#C[Si](C)(C)C)c2c1C>>C#Cc1cccc2oc(C(=O)OCC)c(C)c12 -US20120010228A1,1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1.Fc1ccc(C(CCCCl)c2ccc(F)cc2)cc1>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(c4ccc(F)cc4)c4ccc(F)cc4)CC3)C2=O)c1 -US06376491B1,9,CCOC(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1CN=[N+]=[N-]>>CCOC(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1CN -US20110269763A1,1,CCOC(=O)CN.CCOC(=O)COc1ccc(Br)cc1C=O>>CCOC(=O)C/N=C/c1cc(Br)ccc1OCC(=O)OCC -US04571345,2,C[C@@H](N)C(=O)O.O=C(N[C@H](C(=O)O)C(Cc1ccccc1)C(=O)O)OCc1ccccc1>>C[C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(Cc1ccccc1)C(=O)O)C(=O)O -US08609622B2,8,COc1ccc(Cc2cc([C@]3(OC)O[C@H](CO)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)c(F)c1F>>COc1ccc(Cc2cc([C@]3(OC)O[C@H](C=O)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)c(F)c1F -US08927281B2,1,CC(C)I.Clc1cc(Cl)c2nc[nH]c2n1>>CC(C)n1cnc2c(Cl)cc(Cl)nc21 -US20120149737A1,1,CI.COC(=O)c1cc(Cl)c(O)c(OC(C)C)c1>>COC(=O)c1cc(Cl)c(OC)c(OC(C)C)c1 -US20140066425A1,7,CC(C)(C)OC(=O)n1ccnc1CCCc1ccc([N+](=O)[O-])cn1>>CC(C)(C)OC(=O)n1ccnc1CCCc1ccc(N)cn1 -US20090275558A1,1,CC(C)(C)OC(=O)CBr.COc1cc(C)c(S(=O)(=O)N2CCCCC2CO)c(C)c1>>COc1cc(C)c(S(=O)(=O)N2CCCCC2COCC(=O)OC(C)(C)C)c(C)c1 -US06774241B2,2,O=S(=O)(Cl)c1ccccc1F.c1ccc(COc2cccc3[nH]ccc23)cc1>>O=S(=O)(c1ccccc1F)n1ccc2c(OCc3ccccc3)cccc21 -US20060116366A1,6,COC(=O)c1ccc(CN2C(=O)N(c3ccc(OC(F)(F)F)cc3)CC23CCN(Cc2ccccc2)CC3)cc1>>O=C(O)c1ccc(CN2C(=O)N(c3ccc(OC(F)(F)F)cc3)CC23CCN(Cc2ccccc2)CC3)cc1 -US20040097507A1,2,COc1cc(CN)cc(OC)c1OC.Cc1onc2c1c(=O)n(C1CCCC(C(=O)O)C1)c1cnccc21>>COc1cc(CNC(=O)C2CCCC(n3c(=O)c4c(C)onc4c4ccncc43)C2)cc(OC)c1OC -US06498165B1,2,CCN.C[C@H](Nc1nccc(-n2cnc3ccccc32)n1)c1cccc(C(=O)O)c1>>CCNC(=O)c1cccc([C@H](C)Nc2nccc(-n3cnc4ccccc43)n2)c1 -US20040010141A1,7,N#Cc1ccc(-n2ncc3cc(Oc4ccc([N+](=O)[O-])cn4)ccc32)cc1>>N#Cc1ccc(-n2ncc3cc(Oc4ccc(N)cn4)ccc32)cc1 -US20150225335A1,1,CNC(=O)[C@@](C)(C(=O)NOC1CCCCO1)N(C)C(=O)c1ccc(C#Cc2ccc(C=O)cc2)cc1.COC1CNC1>>CNC(=O)[C@@](C)(C(=O)NOC1CCCCO1)N(C)C(=O)c1ccc(C#Cc2ccc(CN3CC(OC)C3)cc2)cc1 -US20110237573A1,2,CC(=O)N1CCN(c2ccc(N)nc2)CC1.Cc1cc(-c2cc(F)c(CC(=O)O)cc2C)ccn1>>CC(=O)N1CCN(c2ccc(NC(=O)Cc3cc(C)c(-c4ccnc(C)c4)cc3F)nc2)CC1 -US20140163025A1,1,CC(=O)Nc1cccc(B(O)O)c1.COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(O)ccc(F)c43)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5cccc(NC(C)=O)c5)ccc(F)c43)ccc21 -US05843957,6,CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCCCOCc3ccccc3)c2)c2cccnc21>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCCCO)c2)c2cccnc21 -US09018214B2,7,COC[C@H]1CN(C(=O)OC(C)(C)C)[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C3=CCCCC3)cc21>>COC[C@H]1CN(C(=O)OC(C)(C)C)[C@H](C)CN1CC(=O)N1CC(C)(C)c2cnc(C3CCCCC3)cc21 -US20110301155A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)(=O)c1ccc(Oc2cc(-c3ncccc3Cl)cc3c(Br)n[nH]c23)cc1>>CC(C)(C)OC(=O)n1nc(Br)c2cc(-c3ncccc3Cl)cc(Oc3ccc(S(C)(=O)=O)cc3)c21 -US20100298287A1,2,CCC(N)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl.O=C(O)C(F)F>>CCC(NC(=O)C(F)F)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl -US08927541B2,6,CCOC(=O)C1=Cc2c(cnc3ccc(OC)cc23)SC1>>COc1ccc2ncc3c(c2c1)C=C(C(=O)O)CS3 -US04672127,3,O=C1CNC(=O)N1.O=Cc1ccccc1>>O=C1NC(=O)C(=Cc2ccccc2)N1 -US08575360B2,3,CC(C)(NS(=O)C(C)(C)C)c1ccc(Cl)nn1.OCc1ccc(B(O)O)cn1>>CC(C)(NS(=O)C(C)(C)C)c1ccc(-c2ccc(CO)nc2)nn1 -US04579848,6,CC(=O)Nc1nc2ccnc(-c3cccc(NS(=O)(=O)c4ccc(C)cc4)c3)n2n1>>Cc1ccc(S(=O)(=O)Nc2cccc(-c3nccc4nc(N)nn34)c2)cc1 -US20100105739A1,2,CCC(=O)Cl.Cc1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)cc1-c1ccc(CN)cc1>>CCC(=O)NCc1ccc(-c2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2C)cc1 -US20030199491A1,1,CN1CCN(CCCO)CC1.N#Cc1cc2c(Cl)ccnc2cc1O>>CN1CCN(CCCOc2cc3nccc(Cl)c3cc2C#N)CC1 -US20080280892A1,7,CCCCOC(=O)CCc1cc(=O)n(Cc2ccc(OC)cc2)[nH]c1=O>>COc1ccc(Cn2[nH]c(=O)c(CCCO)cc2=O)cc1 -US20040259912A1,1,COC(=O)c1cc([N+](=O)[O-])ccc1O.OC(c1ccccc1F)c1ccccc1F>>COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccccc1F)c1ccccc1F -US06861418B2,3,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.O=C(O)Cc1cccc(Br)c1>>O=C(O)Cc1cccc(-c2cccc3[nH]ccc23)c1 -US07674801B2,3,CCNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1.CCOC(=O)c1sc(Cl)nc1C(=O)N(C)C>>CCNC(=O)Nc1ccc(-c2nc(C(=O)N(C)C)c(C(=O)OCC)s2)cn1 -US20150152069A1,1,CC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(Cl)cc1Nc1ccccc1>>CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(Nc3ccccc3)c2)CC1 -US06838463B2,7,CC#CCOc1cc(C(=O)c2ccccc2)ncn1>>CC#CCOc1cc(C(O)c2ccccc2)ncn1 -US20110237832A1,6,COC(=O)/C=C/C=C/[C@@H](C)C(OC)c1ccc(N(C)C)cc1>>COC(c1ccc(N(C)C)cc1)[C@H](C)/C=C/C=C/C(=O)O -US20100216986A1,3,Brc1ccc[se]1.CCCOc1ccc(-c2ccc(B(O)O)cc2)c(F)c1F>>CCCOc1ccc(-c2ccc(-c3ccc[se]3)cc2)c(F)c1F -US06239159B1,1,COC(=O)CCCCBr.O=[N+]([O-])c1ccc2[nH]ccc2c1>>COC(=O)CCCCn1ccc2cc([N+](=O)[O-])ccc21 -US20150166483A1,1,CC(C)(C)OC(=O)CCOCCOCCO.COc1cc(O)cc([N+](=O)[O-])c1>>COc1cc(OCCOCCOCCC(=O)OC(C)(C)C)cc([N+](=O)[O-])c1 -US20060276433A1,1,CN(C)Cc1ccc(C=O)cc1.NNc1ccc(I)cc1>>CN(C)Cc1ccc(C=NNc2ccc(I)cc2)cc1 -US20150005279A1,6,Cc1ccc(S(=O)(=O)n2c(C3=CCN(C(=O)OC(C)(C)C)CC3)cc3c(F)ccc(C#N)c32)cc1>>Cc1ccc(S(=O)(=O)n2c(C3=CCNCC3)cc3c(F)ccc(C#N)c32)cc1 -US07557213B2,1,COc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1C.N#Cc1cccc(CBr)n1>>COc1ccc(C(=O)c2cn(Cc3cccc(C#N)n3)c3ccccc3c2=O)cc1C -US20070213321A1,1,O=C(CCl)N1CCCc2ccccc21.O=[N+]([O-])c1ccc2nc(S)sc2c1>>O=C(CSc1nc2ccc([N+](=O)[O-])cc2s1)N1CCCc2ccccc21 -US04289711,6,CCOC(=O)C1C(C(C)=O)C1(C)C>>CC(=O)[C@H]1[C@H](C(=O)O)C1(C)C -US20150274664A1,8,N#CC1(CO)CC1C1CCN(c2ncc(Cl)cn2)CC1>>N#CC1(C=O)CC1C1CCN(c2ncc(Cl)cn2)CC1 -US20080300242A1,1,COCCN1CCN(c2ccc(N)c(OC)c2)CC1.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>COCCN1CCN(c2ccc(Nc3nccc(-c4c(-c5ccc(OC)c(C(=O)Nc6c(F)cccc6F)c5)nc5ccccn45)n3)c(OC)c2)CC1 -US05028606,7,CC(=O)Nc1ccc(C(=O)C(C)C)cc1[N+](=O)[O-]>>CC(=O)Nc1ccc(C(O)C(C)C)cc1[N+](=O)[O-] -US20090042964A1,3,C#CC(C)C.O=C(C(=O)c1ccc(OC(F)F)c(C2CC2)c1)c1cccc(Br)c1>>CC(C)C#Cc1cccc(C(=O)C(=O)c2ccc(OC(F)F)c(C3CC3)c2)c1 -US20110105514A1,7,O=C(O)CCc1ccc(C(F)(F)F)c(F)c1F>>OCCCc1ccc(C(F)(F)F)c(F)c1F -US20100210647A1,6,CCOC(=O)c1cc2cccc([N+](=O)[O-])c2[nH]1>>O=C(O)c1cc2cccc([N+](=O)[O-])c2[nH]1 -US20050085487A1,7,CN1CCN(C(=O)c2[nH]c3ccccc3c2C=O)CC1>>CN1CCN(C(=O)c2[nH]c3ccccc3c2CO)CC1 -US07410963B2,3,COc1cc2c(cc1Br)C(c1cccc(C#N)c1)=NCC(=O)N2C.OB(O)c1ccco1>>COc1cc2c(cc1-c1ccco1)C(c1cccc(C#N)c1)=NCC(=O)N2C -US20050234081A1,3,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(Br)c1.Cc1c(B2OC(C)(C)C(C)(C)O2)cccc1C(=O)OC(C)C>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2cccc(C(=O)OC(C)C)c2C)c1 -US20130190338A1,2,CS(=O)(=O)Cl.Nc1cccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1>>CS(=O)(=O)Nc1cccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1 -US20130267729A1,6,CC(C)(C)OC(=O)NCC(=O)NCC(F)(F)F>>NCC(=O)NCC(F)(F)F -US04518596,1,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3c(NCCO)ncnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3c(NCCO)ncnc23)CC1 -US08003649B2,1,CC(=O)c1ccc(N2CCNCC2)cc1.FC(F)(F)c1nnc2ccc(Cl)nn12>>CC(=O)c1ccc(N2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US20140323477A1,8,CCn1c(=O)c(-c2ccc(S(=O)(=O)N(C)C)cc2C)cc2cnc(SC)nc21.O=C(OO)c1cccc(Cl)c1>>CCn1c(=O)c(-c2ccc(S(=O)(=O)N(C)C)cc2C)cc2cnc(S(C)=O)nc21 -US20060100460A1,2,CC(C)(C)c1ccc(OCC(=O)O)cc1.CS(=O)(=O)Nc1c(F)cc(CN)cc1F>>CC(C)(C)c1ccc(OCC(=O)NCc2cc(F)c(NS(C)(=O)=O)c(F)c2)cc1 -US06503903B1,2,CNCc1cc2ccccc2n1Cc1ccc(O)cc1.C[C@H]1Nc2ccc(C(=O)O)cc2CN(C)C1=O>>C[C@H]1Nc2ccc(C(=O)N(C)Cc3cc4ccccc4n3Cc3ccc(O)cc3)cc2CN(C)C1=O -US06034239,6,CCOC(=O)CCc1cc(Br)c2c(c1)CCO2>>O=C(O)CCc1cc(Br)c2c(c1)CCO2 -US04975439,6,CO[C@@H]1CN(CCCC(=O)N2CCCC2)CC[C@@H]1NCc1ccccc1>>CO[C@@H]1CN(CCCC(=O)N2CCCC2)CC[C@@H]1N -US06177419B1,3,C=CCc1cc(OC)c(O)c(B(O)O)c1.COc1ccc(O)c(-c2cccc(-c3cccc(Br)n3)n2)c1>>C=CCc1cc(OC)c(O)c(-c2cccc(-c3cccc(-c4cc(OC)ccc4O)n3)n2)c1 -US20040044011A1,1,COc1ccc(CNc2nc(CCl)nc3sc4c(c23)CCCC4)cc1Cl.NCCCO>>COc1ccc(CNc2nc(CNCCCO)nc3sc4c(c23)CCCC4)cc1Cl -US20090227560A1,4,C[S+](C)(C)=O.O=C1CCC(N2CCOCC2=O)CC1>>O=C1COCCN1C1CCC2(CC1)CO2 -US06951881B2,1,CC(=O)c1c(-c2ccccc2)[nH]c2ccccc12.N=C(N)NN>>CC(=NNC(=N)N)c1c(-c2ccccc2)[nH]c2ccccc12 -US20130059834A1,2,CS(=O)(=O)Cl.Cn1nc(-c2cnc3c(n2)c(C(=O)N[C@@H]2CCCNC2)cn3COCC[Si](C)(C)C)c2ccc(Cl)cc21>>Cn1nc(-c2cnc3c(n2)c(C(=O)N[C@@H]2CCCN(S(C)(=O)=O)C2)cn3COCC[Si](C)(C)C)c2ccc(Cl)cc21 -US20150065482A1,3,CC1(C)OB(C2CC2)OC1(C)C.COC(=O)c1nn(COCC[Si](C)(C)C)c2ncc(Br)cc12>>COC(=O)c1nn(COCC[Si](C)(C)C)c2ncc(C3CC3)cc12 -US20040038855A1,7,COC(=O)C(N)c1cc(F)cc(F)c1>>NC(CO)c1cc(F)cc(F)c1 -US20140336106A1,2,COc1ccc(C[C@H](N)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@]2(C)CO2)cc1OC.C[C@H](NC(=O)CN1CCOCC1)C(=O)[O-]>>COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@]2(C)CO2)cc1OC -US05202346,7,CS(=O)(=O)Nc1ccc(C(=O)C2CCN(CCOc3ccc([N+](=O)[O-])cc3)CC2)cc1>>CS(=O)(=O)Nc1ccc(C(=O)C2CCN(CCOc3ccc(N)cc3)CC2)cc1 -US20090088459A1,3,CC(C)CNCc1ccc(Br)s1.CS(=O)(=O)c1cccc(B(O)O)c1>>CC(C)CNCc1ccc(-c2cccc(S(C)(=O)=O)c2)s1 -US05114944,2,CCCNCCC.O=C(O)Cc1c(-c2ccccc2)nn2cccnc12>>CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nn2cccnc12 -US08664230B2,3,CC(C)(C)OC(=O)N1CCC(Oc2ncnc3ccc(Cl)nc23)CC1.CC1(C)OB(c2cncc(NS(=O)(=O)c3ccccc3)c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(Oc2ncnc3ccc(-c4cncc(NS(=O)(=O)c5ccccc5)c4)nc23)CC1 -US20080300270A1,7,CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(N)c([N+](=O)[O-])c1>>CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(N)c(N)c(Br)c1 -US06187805B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(C)CCc1c[nH]c2ccc(OCc3ccccc3)cc12>>CN(C)CCc1cn(C(=O)OC(C)(C)C)c2ccc(OCc3ccccc3)cc12 -US07534894B2,1,CC(C)(C)OC(=O)NCc1ccc(-c2ccc(O)c(Br)c2)cc1.COC(=O)CBr>>COC(=O)COc1ccc(-c2ccc(CNC(=O)OC(C)(C)C)cc2)cc1Br -US04782058,9,COc1cccc(CC(=O)c2ccccc2)c1.NO>>COc1cccc(CC(=NO)c2ccccc2)c1 -US20050245529A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.CC1CCN(C(C)(C)COc2ccc(I)cc2)CC1>>CC1CCN(C(C)(C)COc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)CC1 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)c(F)ccc2c1N.COc1cccc(F)c1B(O)O>>CCCNC(=O)c1nnc2c(-c3c(F)cccc3OC)c(F)ccc2c1N -US20080293696A1,2,CS(=O)(=O)Cl.O=C(NC1CC1)c1cc(CO)ccn1>>CS(=O)(=O)OCc1ccnc(C(=O)NC2CC2)c1 -US20050261177A1,1,BrCCCCCCCBr.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCCCCCCCBr)cc1 -US04125732,1,COC(=O)C(Br)c1ccc(OCC(C)Oc2ccc(C(F)(F)F)cc2)cc1.Oc1ccc(Oc2ccccc2)cc1>>COC(=O)C(Oc1ccc(Oc2ccccc2)cc1)c1ccc(OCC(C)Oc2ccc(C(F)(F)F)cc2)cc1 -US20120270892A1,3,O=Cc1cccnc1Br.OB(O)c1ccc(C(F)(F)F)s1>>O=Cc1cccnc1-c1ccc(C(F)(F)F)s1 -US07317033B2,2,Cc1cscc1N=C=S.Nc1cc(F)cc(F)c1N>>Cc1cscc1NC(=S)Nc1cc(F)cc(F)c1N -US20060189661A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.N#Cc1cccc(-c2ccc(Br)o2)c1>>N#Cc1cccc(-c2ccc(-c3ccccn3)o2)c1 -US20130217664A1,2,CN.COC(=O)c1ccc(N(C)c2cc3c(cn2)ncn3C)c(C)c1>>CNC(=O)c1ccc(N(C)c2cc3c(cn2)ncn3C)c(C)c1 -US07951824B2,2,CCOC(=O)c1cc(-c2cncc(F)c2)cc(C)n1.Nc1nc(C2CCCC2)cs1>>Cc1cc(-c2cncc(F)c2)cc(C(=O)Nc2nc(C3CCCC3)cs2)n1 -US07625908B2,2,C[C@@H](CN)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12.O=C(O)CO>>C[C@@H](CNC(=O)CO)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12 -US08163793B2,2,N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2)CC1.O=C(Cl)Oc1ccc(F)cc1>>N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2C(=O)Oc2ccc(F)cc2)CC1 -US20070207175A1,2,CCCCOc1cc(CCC(=O)OC)ccc1-c1cccc(CNC)c1.CCOc1ccc(C(=O)Cl)cc1>>CCCCOc1cc(CCC(=O)OC)ccc1-c1cccc(CN(C)C(=O)c2ccc(OCC)cc2)c1 -US20140275172A1,7,CC(=O)C(C)OC(=O)c1cc(Cl)cc2oc(C)c(C)c12>>Cc1oc2cc(Cl)cc(CO)c2c1C -US07381728B2,7,COc1ccc([N+](=O)[O-])cc1N1C[C@H](C)N[C@H](C)C1>>COc1ccc(N)cc1N1C[C@H](C)N[C@H](C)C1 -US20060167020A1,1,NNc1ncnc2c1cnn2-c1nccs1.O=Cc1ccncc1>>C(=NNc1ncnc2c1cnn2-c1nccs1)c1ccncc1 -US20130267482A1,2,CCOC(OCC)[C@H](C)N(Cc1cccc2cccnc12)C(=O)[C@@H](N)CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1.CN(CC(=O)O)NC(=O)NCc1ccc(Cl)cc1>>CCOC(OCC)[C@H](C)N(Cc1cccc2cccnc12)C(=O)[C@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)CN(C)NC(=O)NCc1ccc(Cl)cc1 -US20150152096A1,10,CCOC(=O)C1=C(C)NC(c2nc(C(F)(F)F)cs2)=NC1c1ccc(Cl)cc1Cl.O=C1CCC(=O)N1Br>>CCOC(=O)C1=C(CBr)NC(c2nc(C(F)(F)F)cs2)=NC1c1ccc(Cl)cc1Cl -US20100063066A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1cccc2[nH]nc(I)c12>>CC(C)(C)OC(=O)n1nc(I)c2c([N+](=O)[O-])cccc21 -US06022888,2,CC(C)=CCC/C(C)=C/CO.CNC(=O)O[C@@H]1OC=C(C(=O)O)[C@H]2C[C@@H]3O[C@]3(C)[C@@H]21>>CNC(=O)O[C@@H]1OC=C(C(=O)OC/C=C(\C)CCC=C(C)C)[C@H]2C[C@@H]3O[C@]3(C)[C@@H]21 -US08524753B2,1,CC(C)(C)OC(=O)N[C@@H](CN)COCc1ccccc1.CC(C)(C)OC(=O)N[C@H](C=O)COCc1ccccc1>>CC(C)(C)OC(=O)NC(CNC[C@@H](COCc1ccccc1)NC(=O)OC(C)(C)C)COCc1ccccc1 -US20120245152A1,6,C[C@H](CC(=O)OC(C)(C)C)Oc1ccccc1-c1ccc(C(=O)OCc2ccccc2)c(F)c1>>C[C@H](CC(=O)OC(C)(C)C)Oc1ccccc1-c1ccc(C(=O)O)c(F)c1 -US20090012134A1,1,Fc1ccc(-c2cc3ccc(Br)cc3s2)cc1.O=S([O-])c1ccccc1>>O=S(=O)(c1ccccc1)c1ccc2cc(-c3ccc(F)cc3)sc2c1 -US05366987,3,CCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CCCCCCCCCCC=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US20080032998A1,2,CC1CC(c2cccc(Br)c2)=CCN1.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1CC(c2cccc(Br)c2)=CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US08048901B2,9,Cc1cccc(-c2nc(CO[C@H]3CCC[C@@H](OCCOc4ccccc4B4OC(C)(C)C(C)(C)O4)C3)c(C)o2)c1>>Cc1cccc(-c2nc(CO[C@H]3CCC[C@@H](OCCOc4ccccc4B(O)O)C3)c(C)o2)c1 -US20150038528A1,2,CCOC(=O)C(C)(C)CN.CCc1ccccc1Oc1ccc2c(O)c(C(=O)OC)nc(C#N)c2c1>>CCOC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3CC)ccc2c1O -US06310203B1,1,CCc1cc(-c2nnc3c4ccccc4c(Cl)nn23)no1.OCc1ccccn1>>CCc1cc(-c2nnc3c4ccccc4c(OCc4ccccn4)nn23)no1 -US20010051632A1,6,COc1ccc(-c2cc3cccc(C)n3c2)cc1>>Cc1cccc2cc(-c3ccc(O)cc3)cn12 -US20130281432A1,1,Cn1cc(Br)cc(Br)c1=O.Nc1ccc(N2CC(O)C2)cn1>>Cn1cc(Br)cc(Nc2ccc(N3CC(O)C3)cn2)c1=O -US20130109652A1,3,COc1ccc(B(O)O)cn1.O=c1ccc(Br)cn1Cc1ccc(Cl)cc1F>>COc1ccc(-c2ccc(=O)n(Cc3ccc(Cl)cc3F)c2)cn1 -US20080188520A1,1,CCCI.O=S1(=O)CCCN1[C@@H](c1ccccc1)[C@H](O)c1ccccc1>>CCCO[C@H](c1ccccc1)[C@H](c1ccccc1)N1CCCS1(=O)=O -US20120015969A1,7,COC(=O)c1cncc(O)c1>>COC(=O)[C@@H]1CNC[C@H](O)C1 -US20120207729A1,1,CC(C)(C)OC(=O)Nc1nc2c(Br)cc(CBr)cc2s1.c1cn[nH]c1>>CC(C)(C)OC(=O)Nc1nc2c(Br)cc(Cn3cccn3)cc2s1 -US20030095958A1,8,CC(C)(C)[SiH2]OC(c1ccccc1)(c1ccccc1)C1CN(Cc2ccccc2)CCC1O>>CC(C)(C)[SiH2]OC(c1ccccc1)(c1ccccc1)C1CN(Cc2ccccc2)CCC1=O -US06727249B2,6,O=S(=O)(c1ccccc1)C1CC2(c3ccccc3)C(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CCC1N2Cc1ccccc1>>O=S(=O)(c1ccccc1)[C@@H]1C[C@]2(c3ccccc3)N[C@H]1CC[C@H]2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US06184238B2,1,ClCc1cccnc1.c1ccc2[nH]ccc2c1>>c1cncc(Cn2ccc3ccccc32)c1 -US20080269170A1,2,CC(C)(C)OC(=O)NCCNC1CN(C(=O)OC(C)(C)C)C1.O=S(=O)(Cl)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1>>CC(C)(C)OC(=O)NCCN(C1CN(C(=O)OC(C)(C)C)C1)S(=O)(=O)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1 -US07115611B2,1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.OCc1cnc(-c2ccc(OC(F)(F)F)cc2)cc1C(F)(F)F>>CCOC(=O)C(C)(C)Oc1ccc(OCc2cnc(-c3ccc(OC(F)(F)F)cc3)cc2C(F)(F)F)cc1C -US20110275797A1,1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(O)ccc1OCc1ccccc1.CN1CCN(CCCBr)CC1>>CN1CCN(CCCOc2ccc(OCc3ccccc3)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)OC(C)(C)C)c2)CC1 -US20150126488A1,1,CN(C)C(=O)CCl.N#Cc1nc(-c2ccc(OCCC3CCNCC3)c(C(F)(F)F)c2)c2ccn(CC3CCCO3)c2n1>>CN(C)C(=O)CN1CCC(CCOc2ccc(-c3nc(C#N)nc4c3ccn4CC3CCCO3)cc2C(F)(F)F)CC1 -US20100041892A1,9,BrC(Br)(Br)Br.OCc1ccc(C(F)(F)F)cc1Cl>>FC(F)(F)c1ccc(CBr)c(Cl)c1 -US05786374,9,CC(=O)c1noc2ccccc12.NO>>CC(=NO)c1noc2ccccc12 -US07368578B2,1,COc1cc(C=O)ccc1O.Cc1nc(-c2ccccc2)sc1CCl>>COc1cc(C=O)ccc1OCc1sc(-c2ccccc2)nc1C -US20050096380A1,7,CCCCOc1cc2c(cc1/C(C)=C(/F)C(=O)OCC)C(C(C)C)=CC(C)(C)O2>>CCCCOc1cc2c(cc1/C(C)=C(/F)CO)C(C(C)C)=CC(C)(C)O2 -US20130231306A1,7,CNC(=O)c1cc(C2CCC(=O)CC2)ccc1N>>CNC(=O)c1cc(C2CCC(O)CC2)ccc1N -US07812017B2,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc2c(C=O)cccc2n1S(=O)(=O)c1ccccc1>>Cc1cc2c(CN3CCN(C(=O)OC(C)(C)C)CC3)cccc2n1S(=O)(=O)c1ccccc1 -US04560692,2,CCCN.O=C(Cl)C1CCN(c2cc(-c3ccccc3)nc3ccc(F)cc23)CC1>>CCCNC(=O)C1CCN(c2cc(-c3ccccc3)nc3ccc(F)cc23)CC1 -US08158820B2,2,Brc1cnc(NCc2ccccc2)nc1.CCS(=O)(=O)Cl>>CCS(=O)(=O)N(Cc1ccccc1)c1ncc(Br)cn1 -US20100010035A1,8,CCc1cc(N)c(CO)c(CC)n1>>CCc1cc(N)c(C=O)c(CC)n1 -US20130261125A1,1,CC(C)(C)OC(=O)NC1CCCC(=O)C1.NCc1ccccc1>>CC(C)(C)OC(=O)NC1CCCC(=NCc2ccccc2)C1 -US20110124633A1,7,O=C(O)c1ccc2cc[nH]c2c1>>OCc1ccc2cc[nH]c2c1 -US05576336,9,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCC(O)CC1>>CC(C)(C)OC(=O)N1CCC(Br)CC1 -US06635645B1,3,Brc1ccc(Br)nc1.OB(O)c1ccccc1>>Brc1ccc(-c2ccccc2)nc1 -US20060063940A1,1,Nc1ccc(OCCCN2CCCCC2)cc1.O=C1Nc2ccc(F)cc2C1=CO>>O=C1Nc2ccc(F)cc2C1=CNc1ccc(OCCCN2CCCCC2)cc1 -US20150158858A1,1,CC(C)(C)OC(=O)CBr.O=Cc1cn[nH]c1>>CC(C)(C)OC(=O)Cn1cc(C=O)cn1 -US20140228405A1,2,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(N)cc1.O=C(Cl)c1cccc(Br)c1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(NC(=O)c2cccc(Br)c2)cc1 -US20080139484A1,3,C=CCC(=O)O.Cc1cccc2c1c(Cc1ccc(Br)cc1)cn2[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>Cc1cccc2c1c(Cc1ccc(/C=C/CC(=O)O)cc1)cn2[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US05466697,1,CCI.O=c1[nH]cc(-c2ccccc2)c2ncccc12>>CCn1cc(-c2ccccc2)c2ncccc2c1=O -US20140303177A1,7,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(Cl)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(CN)(c2ccc(Cl)cc2)CC1 -US20110124636A1,6,CC(C)(C)OC(=O)N1[C@H](CNCc2ccccc2)C[C@@H]2C[C@@H]21>>CC(C)(C)OC(=O)N1[C@H](CN)C[C@@H]2C[C@@H]21 -US07595397B2,2,CN=C=O.Clc1ccccc1-c1ccc(CN2CCNC(c3ccccc3)C2)cc1>>CNC(=O)N1CCN(Cc2ccc(-c3ccccc3Cl)cc2)CC1c1ccccc1 -US04920128,7,CNC(=O)Cn1nc(N)c2cc3cc(OC)ccc3nc21>>CNCCn1nc(N)c2cc3cc(OC)ccc3nc21 -US06380230B1,6,COC(=O)Cn1c(C(=O)Nc2nc(-c3cc(OC)c(Cl)cc3OC)c(CCC3CCCCC3)s2)cc2cc(C)cc(C)c21>>COc1cc(-c2nc(NC(=O)c3cc4cc(C)cc(C)c4n3CC(=O)O)sc2CCC2CCCCC2)c(OC)cc1Cl -US20040138223A1,2,CCc1ccc(NCCN2CCCCC2)cc1.O=C(O)C1CCCc2c(OCc3ccccc3)cccc21>>CCc1ccc(N(CCN2CCCCC2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cc1 -US09096600B2,6,COc1c(C(C)NC(=O)OCc2ccccc2)cc(Cl)c(Cl)c1C1CN(C(=O)OC(C)(C)C)C1>>COc1c(C(C)N)cc(Cl)c(Cl)c1C1CN(C(=O)OC(C)(C)C)C1 -US07960374B2,2,CC1c2c(ccc3[nH]ccc23)OCCN1C(=O)OC(C)(C)C.Cc1nc(S(=O)(=O)Cl)cn1C>>Cc1nc(S(=O)(=O)n2ccc3c4c(ccc32)OCCN(C(=O)OC(C)(C)C)C4C)cn1C -US20030236250A1,6,O=C1CN(Cc2ccccc2)CCN1c1ccccn1>>O=C1CNCCN1c1ccccn1 -US08703761B2,6,CC(C)(NC(=O)OCc1ccccc1)C(=O)Nc1nc(-c2ccc(F)cc2)c(Oc2ccc(F)cc2)s1>>CC(C)(N)C(=O)Nc1nc(-c2ccc(F)cc2)c(Oc2ccc(F)cc2)s1 -US20100113510A1,1,CC(C)(CN)CO.COC(=O)C(C)(Br)c1ccc(Cl)cc1>>COC(=O)C(C)(NCC(C)(C)CO)c1ccc(Cl)cc1 -US06576766B1,1,BrCC1CCCCC1.CC(=O)c1ccc(O)cc1>>CC(=O)c1ccc(OCC2CCCCC2)cc1 -US20100069388A1,1,CCOC(=O)c1cnc(Cl)c(Cl)c1.NCCOc1ccccc1>>CCOC(=O)c1cnc(NCCOc2ccccc2)c(Cl)c1 -US20050197350A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](CNC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1>>NC1CCC(CNC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US04356121,4,N#CN.O=C(Cl)CCCCCl>>N#CN1CCCCC1=O -US04798838,1,CCOC(=O)C(C)(C)CCCBr.O=C(CCCCCn1ccnc1)Nc1ccc(O)cc1>>CCOC(=O)C(C)(C)CCCOc1ccc(NC(=O)CCCCCn2ccnc2)cc1 -US07074801B1,3,Brc1ccc2ncc(I)n2c1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cnc3ccc(Br)cn23)cc1 -US20080153809A1,1,Clc1ncccn1.O=C(O)C1=CCNCC1>>O=C(O)C1=CCN(c2ncccn2)CC1 -US20120108574A1,6,Cc1ccc(-c2nc3n(c2-c2ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc2)-c2cccnc2Nc2ccccc2-3)cc1N>>Cc1ccc(-c2nc3n(c2-c2ccc(C4(N)CCC4)cc2)-c2cccnc2Nc2ccccc2-3)cc1N -US20150057260A1,1,CNOC.NC(=O)c1cc(Cl)nc(Cl)n1>>CON(C)c1cc(C(N)=O)nc(Cl)n1 -US20100298384A1,1,C#CCBr.c1cncc(-c2c[nH]cn2)c1>>C#CCn1cnc(-c2cccnc2)c1 -US20140113877A1,1,BrCc1ccccc1.COc1cc(F)ccc1-c1cc2[nH]c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c2s1>>COc1cc(F)ccc1-c1cc2c(s1)c(=O)n(C1CCN(C(=O)OC(C)(C)C)CC1)c(=O)n2Cc1ccccc1 -US20100286126A1,1,CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(NN)nc32)[C@H](O)[C@@H]1O.O=CC1CCCCC1>>CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(NN=CC4CCCCC4)nc32)[C@H](O)[C@@H]1O -US20100286142A1,6,C[Si](C)(C)C#Cc1cnc2[nH]ccc2c1>>C#Cc1cnc2[nH]ccc2c1 -US09060519B2,9,CC(=O)c1sc(-c2cccnc2)nc1Cl.NO>>CC(=NO)c1sc(-c2cccnc2)nc1Cl -US20140315888A1,9,Brc1cnc2nc(N3CCNCC3)c3nncn3c2c1.[C-]#N>>N#Cc1cnc2nc(N3CCNCC3)c3nncn3c2c1 -US20120004243A1,1,CC(C)N.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(OCc2ccc(CO)cn2)cc1>>Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(OCc2ccc(CNC(C)C)cn2)cc1 -US20130150325A1,1,Cc1cc(/C(F)=C/c2ccc(C(C)(C)C(F)(F)F)cc2)nn1Cc1cccc(Br)c1.OC1CCNCC1>>Cc1cc(/C(F)=C/c2ccc(C(C)(C)C(F)(F)F)cc2)nn1Cc1cccc(N2CCC(O)CC2)c1 -US08273772B2,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CC(C)(C)c1ccccc1Oc1ncccc1Nc1nc(C(F)(F)F)c(Br)s1>>C=C(OCC)c1sc(Nc2cccnc2Oc2ccccc2C(C)(C)C)nc1C(F)(F)F -USRE039265E1,1,CS(=O)(=O)OCCC1COc2ccccc2O1.Fc1ccc2c(C3CCNCC3)noc2c1>>Fc1ccc2c(C3CCN(CCC4COc5ccccc5O4)CC3)noc2c1 -US20090270360A1,6,CCOC(=O)C1C(C(=O)Nc2ccc(Cl)cc2)C1C(=O)Nc1ccc(-n2ccccc2=O)cc1F>>O=C(O)C1C(C(=O)Nc2ccc(Cl)cc2)C1C(=O)Nc1ccc(-n2ccccc2=O)cc1F -US05593970,2,CCNCC.COc1ccc(OC)c(C(=O)O)c1>>CCN(CC)C(=O)c1cc(OC)ccc1OC -US06281227B1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1=O.O=[N+]([O-])c1ccc(CBr)cc1>>CC(C)(C)OC(=O)N[C@H]1CCN(Cc2ccc([N+](=O)[O-])cc2)C1=O -US20050245543A1,3,CC(c1ccc(-c2ccc(Br)cc2)cc1)N1CCCC1.OB(O)c1cncnc1>>CC(c1ccc(-c2ccc(-c3cncnc3)cc2)cc1)N1CCCC1 -US20100292255A1,2,CC(=O)Cl.Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCC(N)C1CC1>>CC(=O)NC(CCn1c(Sc2cc3c(cc2Br)OCO3)nc2c(N)ncnc21)C1CC1 -US20120226037A1,6,Cc1cc(C)c(Oc2nc(Nc3ccc(C#N)cc3)nc3c2ccn3Cc2ccccc2)c(C)c1>>Cc1cc(C)c(Oc2nc(Nc3ccc(C#N)cc3)nc3[nH]ccc23)c(C)c1 -US05674906,6,CC(C)(C)OC(=O)NCC(N)=O>>NCC(N)=O -US05234946,1,O=Cc1cccc(CBr)c1.Oc1cccc(Br)c1>>O=Cc1cccc(COc2cccc(Br)c2)c1 -US08501757B2,1,CI.Clc1cc(Br)cc(Nc2cncnc2)c1>>CN(c1cncnc1)c1cc(Cl)cc(Br)c1 -US20100190688A1,6,CC(C(=O)NC1CCc2ccn3c2C1C(=O)CC(C(=O)NC1CCCc2ccccc21)C3)N(C)C(=O)OC(C)(C)C>>CNC(C)C(=O)NC1CCc2ccn3c2C1C(=O)CC(C(=O)NC1CCCc2ccccc21)C3 -US05864039,1,BrCCCCCSc1ccccc1.COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1>>COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCCCSc2ccccc2)CC1 -US08178533B2,10,Cc1nn(C(=O)OC(C)(C)C)c2ncc(Br)cc12.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)n1nc(CBr)c2cc(Br)cnc21 -US20080280836A1,3,C#Cc1cncn1C.CC(=O)O[C@@H](CC[C@H]1C(=O)N(c2ccc(OS(=O)(=O)C(F)(F)F)cc2)[C@@H]1c1ccc(-c2ccc(C#CCC(C(=O)OCc3ccccc3)C(=O)OCc3ccccc3)cc2)cc1OCc1ccccc1)c1ccc(F)cc1>>CC(=O)O[C@@H](CC[C@H]1C(=O)N(c2ccc(C#Cc3cncn3C)cc2)[C@@H]1c1ccc(-c2ccc(C#CCC(C(=O)OCc3ccccc3)C(=O)OCc3ccccc3)cc2)cc1OCc1ccccc1)c1ccc(F)cc1 -US20090075980A1,6,CCCn1nc2c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc3ccccc3c2c1CCCCOC(C)=O>>CCCn1nc2c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc3ccccc3c2c1CCCCO -US20060235013A1,6,CCOC(=O)c1n[nH]c2c1CN(Cc1ccccc1)C2>>CCOC(=O)c1n[nH]c2c1CNC2 -US04457931,7,CC(C(=O)Nc1ccc2c(c1)OCO2)N1CCN(c2ccccn2)CC1>>CC(CNc1ccc2c(c1)OCO2)N1CCN(c2ccccn2)CC1 -US04179561,7,CCOC(=O)c1cc2c3ccccc3[nH]c(=O)n2n1>>O=c1[nH]c2ccccc2c2cc(CO)nn12 -US08143256B2,1,CC(C)(C)OC(=O)NCCCCN1CCNCC1.CCOC(=O)CCCCBr>>CCOC(=O)CCCCN1CCN(CCCCNC(=O)OC(C)(C)C)CC1 -US06313365B1,3,C=CCC(CC=C)OC(=O)c1ccccc1>>O=C(OC1CC=CC1)c1ccccc1 -US20130190352A1,9,CCOC(=O)N1CCC(O)(c2ccccc2Sc2ccc(C)cc2)CC1>>CCOC(=O)N1CCC(c2ccccc2Sc2ccc(C)cc2)CC1 -US20060052408A1,9,ClC(Cl)(Cl)Cl.OC[C@]1(c2ccccc2)C[C@H]1COCc1ccccc1>>ClC[C@]1(c2ccccc2)C[C@H]1COCc1ccccc1 -US20150133425A1,2,Cc1ccccc1N.O=C(O)C1CCc2c(sc3ncnc(Nc4ccc5[nH]ncc5c4)c23)C1>>Cc1ccccc1NC(=O)C1CCc2c(sc3ncnc(Nc4ccc5[nH]ncc5c4)c23)C1 -US07498346B2,2,COCCOc1ccc(N(Cc2cnccc2C)C2CCN([C@H](C)CCN)CC2)cc1.Cc1ccnc(Cl)c1C(=O)O>>COCCOc1ccc(N(Cc2cnccc2C)C2CCN([C@H](C)CCNC(=O)c3c(C)ccnc3Cl)CC2)cc1 -US20110275622A1,1,CC(C)(C)[Si](C)(C)OCc1cc([C@@H](O)CN)ccc1O.COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5ccc(CCCCC=O)cc5)c4)cc23)c1>>COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5ccc(CCCCCNC[C@H](O)c6ccc(O)c(CO[Si](C)(C)C(C)(C)C)c6)cc5)c4)cc23)c1 -US20070293521A1,1,COC(=O)C1Cc2cc(N)ccc2O1.Fc1cnc(Cl)nc1Nc1ccc(OC(F)(F)F)c(Cl)c1>>COC(=O)C1Cc2cc(Nc3ncc(F)c(Nc4ccc(OC(F)(F)F)c(Cl)c4)n3)ccc2O1 -US04080461,1,N#CSCCl.Nc1cc(S)ccc1[N+](=O)[O-]>>N#CSCSc1ccc([N+](=O)[O-])c(N)c1 -US20110077399A1,1,CCn1cc(-c2ccc(Cl)cc2Cl)nc1/C=C/c1ccc(-c2ccc(O)cc2)cc1.COC(=O)c1ccc(F)cc1Br>>CCn1cc(-c2ccc(Cl)cc2Cl)nc1/C=C/c1ccc(-c2ccc(Oc3ccc(C(=O)OC)c(Br)c3)cc2)cc1 -US20150252046A1,3,CCC(=O)N1CC2CN(C(=O)c3ccc(Br)cc3)CC2C1.OB(O)c1ccc2cnccc2c1>>CCC(=O)N1CC2CN(C(=O)c3ccc(-c4ccc5cnccc5c4)cc3)CC2C1 -US20150175623A1,9,CC(C)[Si](Oc1ccc(Br)c(I)c1Cl)(C(C)C)C(C)C.N#C[Cu]>>CC(C)[Si](Oc1ccc(Br)c(C#N)c1Cl)(C(C)C)C(C)C -US20090131468A1,3,C#CC(C)C.NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)cc1>>CC(C)C#Cc1ccc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cc1 -US04845110,7,N#Cc1cccc(C=CCO)c1>>N#Cc1cccc(CCCO)c1 -US20110009454A1,1,CCCCCI.Nc1ncccc1C(=O)NCc1cccc(O)c1>>CCCCCOc1cccc(CNC(=O)c2cccnc2N)c1 -US20140288123A1,6,COC(=O)c1ccc(C(CC(C)C)Oc2ccccc2)cc1>>CC(C)CC(Oc1ccccc1)c1ccc(C(=O)O)cc1 -US08153805B2,3,Cc1c(Br)cccc1C(=O)N1CCC(N2CCCC2)CC1.OB(O)c1cccc(OC(F)(F)F)c1>>Cc1c(C(=O)N2CCC(N3CCCC3)CC2)cccc1-c1cccc(OC(F)(F)F)c1 -US20140005168A1,3,CC(C)(C)OC(=O)N1CCN(c2cccc(-n3ncc4cnc(Cl)cc43)n2)CC1.CCCC[Sn](CCCC)(CCCC)c1cnccn1>>CC(C)(C)OC(=O)N1CCN(c2cccc(-n3ncc4cnc(-c5cnccn5)cc43)n2)CC1 -US20120196884A1,2,Cc1cc(N=C=O)ccc1[N+](=O)[O-].Cc1ccccc1N>>Cc1ccccc1NC(=O)Nc1ccc([N+](=O)[O-])c(C)c1 -US20070060577A1,1,CCOC(=O)CCCl.Nc1ccc2c(c1)CCC2>>CCOC(=O)CCNc1ccc2c(c1)CCC2 -US20020028807A1,1,CCN.Cc1cc(Cl)nc(Cl)c1NC(=O)c1cccnc1Cl>>CCNc1ncccc1C(=O)Nc1c(C)cc(Cl)nc1Cl -US06200980B1,2,CCCc1nn(C)c2c(=O)[nH]c(-c3cc(N)ccc3OCC)nc12.O=S(=O)(Cl)CCCN1CCOCC1>>CCCc1nn(C)c2c(=O)[nH]c(-c3cc(NS(=O)(=O)CCCN4CCOCC4)ccc3OCC)nc12 -US20120122842A1,7,CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(C(=O)OC)cc3C2)cc1>>CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(CO)cc3C2)cc1 -US20090137548A1,3,C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1I.O=[N+]([O-])c1ccc(Cl)c(B(O)O)c1>>C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1-c1cc([N+](=O)[O-])ccc1Cl -US20130244966A1,2,Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1)OCC(Cl)(Cl)Cl -US20080194670A1,3,Brc1ccc(Br)cc1.C=CCBr>>C=CCc1ccc(Br)cc1 -US08552205B2,6,C[C@@H](OC(C)(C)C)[C@H](NC(=O)OC(C)(C)C)C(=O)NC1(c2ncccn2)CC1>>C[C@@H](OC(C)(C)C)[C@H](N)C(=O)NC1(c2ncccn2)CC1 -US20110166137A1,5,CNc1nccc(-c2cc(NC3CCNCC3)c3cc(OC)ccc3c2)n1.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>CNc1nccc(-c2cc(NC3CCN(C(=O)OCC4c5ccccc5-c5ccccc54)CC3)c3cc(OC)ccc3c2)n1 -US05747537,3,O=C(O)CCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccco1>>O=C(O)CCCCCCC=Cc1ccco1 -US07462617B2,2,CS(=O)(=O)c1ccc(-c2ccccc2)c(C(=O)O)c1.c1ccc(N2CCNCC2)cc1>>CS(=O)(=O)c1ccc(-c2ccccc2)c(C(=O)N2CCN(c3ccccc3)CC2)c1 -US05288730,1,Cc1cc(C)cc(CBr)c1.OC1C2CCN(CC2)C1C(Cc1ccccc1)c1ccccc1>>Cc1cc(C)cc(COC2C3CCN(CC3)C2C(Cc2ccccc2)c2ccccc2)c1 -US20090005353A1,1,BrCCc1ccccc1.CC(C)(C)N1C(=O)C(NC2CCNCC2)=C(c2ccccc2)S1(=O)=O>>CC(C)(C)N1C(=O)C(NC2CCN(CCc3ccccc3)CC2)=C(c2ccccc2)S1(=O)=O -US05455252,3,CCCCCCc1ccc(N)c(Br)c1.OB(O)c1ccccc1>>CCCCCCc1ccc(N)c(-c2ccccc2)c1 -US20020161033A1,1,CO.O=NC1=C(O)C(=Cc2ccccc2)NC1=O>>COC1=C(N=O)C(=O)NC1=Cc1ccccc1 -US20060041123A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O>>CC(C)(C)OC(=O)N[C@@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O -US07482375B2,9,CCc1c(Oc2ccc(C#N)cc2)c(OC)nn1CC(=O)O.N>>CCc1c(Oc2ccc(C#N)cc2)c(OC)nn1CC(N)=O -US20150166600A1,2,CCCCCCCCCC(=O)N1C[C@H](O)C[C@H]1C(=O)O.COC(=O)[C@@H]1CCCN1>>CCCCCCCCCC(=O)N1C[C@H](O)C[C@H]1C(=O)N1CCC[C@H]1C(=O)OC -US20030109563A1,1,FC(F)=C(F)CCBr.Sc1ncco1>>FC(F)=C(F)CCSc1ncco1 -US08703807B2,8,CC(C)Oc1ccc(N2CCC3(CCC(O)CC3)C2=O)cc1>>CC(C)Oc1ccc(N2CCC3(CCC(=O)CC3)C2=O)cc1 -US04820828,2,COC(=O)C=Cc1ccc(OC)c(OC)c1.NO>>COc1ccc(C=CC(=O)NO)cc1OC -US05202335,6,O=C(OCc1ccccc1)[C@H](CC(=O)N1C[C@@H]2CCCC[C@@H]2C1)Cc1ccccc1>>O=C(O)[C@H](CC(=O)N1C[C@@H]2CCCC[C@@H]2C1)Cc1ccccc1 -US20100041713A1,3,C#CCCO.COc1cc(Cl)ccc1Br>>COc1cc(Cl)ccc1C#CCCO -US08957070B2,1,CCOC(=O)c1cc2cccc([N+](=O)[O-])c2[nH]1.COCCl>>CCOC(=O)c1cc2cccc([N+](=O)[O-])c2n1COC -US04162328,2,C#CCOCc1ccc(CO)cc1.O=C(O)C1CC1>>C#CCOCc1ccc(COC(=O)C2CC2)cc1 -US20150080549A1,6,CC(C)SSC(CN=[N+]=[N-])C[C@@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H]1[C@H](COP(=O)(O)O[C@H]2C[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(=O)(O)O)O[C@@H](n2cnc3c(N)ncnc32)[C@@H]1O>>CC(C)SSC(CN=[N+]=[N-])C[C@@H](N)C(=O)O[C@@H]1[C@H](COP(=O)(O)O[C@H]2C[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(=O)(O)O)O[C@@H](n2cnc3c(N)ncnc32)[C@@H]1O -US07550495B2,1,CC(=O)Nc1ccc(F)c([N+](=O)[O-])c1.NCC1CCC(F)(F)CC1>>CC(=O)Nc1ccc(NCC2CCC(F)(F)CC2)c([N+](=O)[O-])c1 -US08501746B2,1,CCOC(=O)c1sc(-n2ccc(O)cc2=O)nc1C.CI>>CCOC(=O)c1sc(-n2ccc(OC)cc2=O)nc1C -US20140080798A1,1,CC(C)(C)OC(=O)N(CCO)Cc1ccc(N)cc1.FC(F)(F)c1cnc(Cl)nc1Cl>>CC(C)(C)OC(=O)N(CCO)Cc1ccc(Nc2ncc(C(F)(F)F)c(Cl)n2)cc1 -US05665718,1,CCCNCCC.O=C1c2ccccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCCN12>>CCCN(CCC)Cc1nc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2ccccc2-3)no1 -US20110077254A1,6,O=C(OCC1c2ccccc2-c2ccccc21)N1C[C@H](C(F)F)[C@H]2OC[C@H](O)[C@H]21>>O[C@H]1CO[C@@H]2[C@@H](C(F)F)CN[C@H]12 -US07427632B2,1,C=O.O=C(NC(COCC1CCNCC1)c1ccc(F)cc1)c1ccc2c(Cl)c[nH]c2c1>>CN1CCC(COCC(NC(=O)c2ccc3c(Cl)c[nH]c3c2)c2ccc(F)cc2)CC1 -US20050075377A1,2,CCCCCCCNCCc1cccc(OC(C)(CC)C(=O)OCc2ccccc2)c1.O=C(O)c1ccc(F)cc1F>>CCCCCCCN(CCc1cccc(OC(C)(CC)C(=O)OCc2ccccc2)c1)C(=O)c1ccc(F)cc1F -US20100317657A1,3,COCc1ncc(B2OC(C)(C)C(C)(C)O2)cc1OC(C)C.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>COCc1ncc(-c2ccc3ncc4c(c3c2)n(-c2cn(C)nc2C)c(=O)n4C)cc1OC(C)C -US20050148624A1,9,COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccccc1>>COC(=O)c1c(-c2ccccc2)c2ccccc2c(=O)n1Cc1ccccc1 -US05618806,6,COC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)CCc3ccc(C(=O)O)cc3)CC[C@@H]12>>C[C@]12CC[C@@H]3c4ccc(C(=O)O)cc4CC[C@H]3[C@@H]1CC[C@@H]2C(=O)CCc1ccc(C(=O)O)cc1 -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12.O=Cc1cccs1>>FC(F)(F)c1nnc2ccc(N3CCN(Cc4cccs4)CC3)nn12 -US20130236434A1,9,CS(=O)(=O)O[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N(Cc1cccs1)Cc1cccs1.[C-]#N>>N#C[C@H](CCCCNC(=O)OCc1ccccc1)C(=O)N(Cc1cccs1)Cc1cccs1 -US20150031686A1,1,COc1ccc(-c2cnco2)cc1N.O=Cc1csc(Br)c1>>COc1ccc(-c2cnco2)cc1NCc1csc(Br)c1 -US08148383B2,1,CCCI.CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)[nH]c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CCC)c2ncnn12 -US06124314,2,C#CCN.O=C(Cl)OCc1ccccc1>>C#CCNC(=O)OCc1ccccc1 -US07560546B2,7,CCOC(=O)c1[nH]c2cc([N+](=O)[O-])c(Br)cc2c1S(=O)(=O)N1CCOCC1>>CCOC(=O)c1[nH]c2cc(N)c(Br)cc2c1S(=O)(=O)N1CCOCC1 -US20100029722A1,6,CCOC(=O)c1sc(-n2cc(CCCc3ccccc3)nn2)nc1C>>Cc1nc(-n2cc(CCCc3ccccc3)nn2)sc1C(=O)O -US20150133470A1,1,COC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1>>COC(=O)[C@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)NCc1ccccc1 -US20040072818A1,2,CNCc1ccccc1.Nc1cc(N2CCN(C(=O)NCC(=O)O)CC2)c2ccc(Cl)cc2n1>>CN(Cc1ccccc1)C(=O)CNC(=O)N1CCN(c2cc(N)nc3cc(Cl)ccc23)CC1 -US08273769B2,6,CC(C)(C)OC(=O)COc1ccc(Cl)cc1C#Cc1ccc2c(c1)S(=O)(=O)CC2>>O=C(O)COc1ccc(Cl)cc1C#Cc1ccc2c(c1)S(=O)(=O)CC2 -US08791102B2,2,Cc1nc(C)n(CC(=O)O)n1.N[C@@H](COCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1>>Cc1nc(C)n(CC(=O)N[C@@H](COCc2ccccc2)C(=O)Nc2ccc(Oc3ccc(F)cc3)cc2)n1 -US20100331378A1,8,CC(O)c1ncc(Cn2ncc(NC(=O)c3ncoc3-c3ccccc3)n2)o1>>CC(=O)c1ncc(Cn2ncc(NC(=O)c3ncoc3-c3ccccc3)n2)o1 -US20150218144A1,9,BrC(Br)(Br)Br.COc1ccc(C(O)[C@@H]2CN(C(=O)OC(C)(C)C)CCO2)cn1>>COc1ccc(C(Br)[C@@H]2CN(C(=O)OC(C)(C)C)CCO2)cn1 -US20110021523A1,2,N#Cc1cccc(S(=O)(=O)Cl)c1.Nc1ccc(Cl)cc1C(=O)c1ccncc1>>N#Cc1cccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2ccncc2)c1 -US05670504,1,COc1cccc(NN=C(Cl)C(C)=O)c1.Sc1ccc(Cl)cc1>>COc1cccc(NN=C(Sc2ccc(Cl)cc2)C(C)=O)c1 -US20050131014A1,1,Nc1cccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1ccc(-c2ccc(C(=O)O)cc2)cc1>>O=C(O)c1ccc(-c2ccc(CNc3cccc(-c4c(C(=O)c5ccccc5)cnc5c(C(F)(F)F)cccc45)c3)cc2)cc1 -US20080312232A1,7,O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ncn1)N1CCCC1>>Nc1ccc(Oc2cc(NC(=O)N3CCCC3)ncn2)c(F)c1 -US20120088746A1,2,Cc1cc([C@@H](C)N)ncc1NS(C)(=O)=O.O=C(O)c1ccc2cc(C(F)(F)F)ccc2c1>>Cc1cc([C@@H](C)NC(=O)c2ccc3cc(C(F)(F)F)ccc3c2)ncc1NS(C)(=O)=O -US20120071481A1,3,CCOC(=O)c1noc(Br)c1C.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1noc(-c2ccc(C(F)(F)F)cc2)c1C -US04616024,4,CCOC(=O)C(=O)CBr.CCOC(=O)C1=C(COCC(N)=S)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl>>CCOC(=O)C1=C(COCc2nc(C(=O)OCC)cs2)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl -US08895565B2,1,CCOC(=O)c1ccc(CN)o1.Cc1ncnc(Cl)c1C#Cc1ccc(C(F)(F)F)cc1>>CCOC(=O)c1ccc(CNc2ncnc(C)c2C#Cc2ccc(C(F)(F)F)cc2)o1 -US07858649B2,1,Brc1c[nH]cn1.O=[N+]([O-])c1cccc(F)c1>>O=[N+]([O-])c1cccc(-n2cnc(Br)c2)c1 -US20060217424A1,6,COc1cccc(CN(C)C)c1SC>>CSc1c(O)cccc1CN(C)C -US20100331378A1,7,CC1(c2cccc(Cn3ncc([N+](=O)[O-])n3)n2)OCCO1>>CC1(c2cccc(Cn3ncc(N)n3)n2)OCCO1 -US08129376B2,2,Brc1ccccc1OC1CCNCC1.O=C(O)CNC(=O)c1ccc(-c2ccccc2)cc1>>O=C(NCC(=O)N1CCC(Oc2ccccc2Br)CC1)c1ccc(-c2ccccc2)cc1 -US20090203667A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=C(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1>>CCOC(=O)C=C(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1 -US09040515B2,9,CCOC(=O)c1c(Cl)ccc(Cl)c1CBr.[C-]#N>>CCOC(=O)c1c(Cl)ccc(Cl)c1CC#N -US20120316338A1,1,BrCc1ccc(Br)cc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(Br)cc2)CC1 -US20100317582A1,1,C[C@@H](N)c1cccc2ccccc12.O=C1CCC[C@@H](c2ccccc2)C1>>C[C@@H](NC1CCC[C@@H](c2ccccc2)C1)c1cccc2ccccc12 -US20120225868A1,2,N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1)c1ccccc1 -US20090124619A1,2,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCC1CCCNC1.N#Cc1ccccc1S(=O)(=O)Cl>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NC[C@@H]1CCCN(S(=O)(=O)c2ccccc2C#N)C1 -US20090149517A1,2,Cc1ccc(C(N)=O)c(N)c1.O=C(O)c1csc(Br)n1>>Cc1ccc(C(N)=O)c(NC(=O)c2csc(Br)n2)c1 -US20080004309A1,9,CCOC(=O)c1nc(Br)c2nc(-c3ccccc3)sc2c1O.[C-]#N>>CCOC(=O)c1nc(C#N)c2nc(-c3ccccc3)sc2c1O -US20110118262A1,2,N=C(N)NC(=O)OCc1ccccc1.O=C(O)c1ccc(C2CCN(C(=O)c3ccc[nH]3)C2)c(C(F)(F)F)c1>>N=C(NC(=O)OCc1ccccc1)NC(=O)c1ccc(C2CCN(C(=O)c3ccc[nH]3)C2)c(C(F)(F)F)c1 -US20050090498A1,7,CC(=O)OC(=O)c1ccc2c(c1)C(=C1C=Cc3ccccc3N1)C(=O)N2>>O=C1Nc2ccc(C(=O)O)cc2C1=C1C=Cc2ccccc2N1 -US05446161,6,CC(C)(C)OC(=O)[C@@H]1CCCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)[C@@H]1CCCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O -US07230020B2,2,Cc1nc2c(Cl)c(N)ccc2s1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>Cc1nc2c(Cl)c(NC(=O)c3cc(Cl)cc(Cl)c3)ccc2s1 -US20110230462A1,1,C[Si](C)(C)CCOCn1cc(C(=O)N[C@@H](C(=O)N2CC(C#N)C2)C2CC2)c2nc(-c3cc4nccc(Cl)c4s3)cnc21.OCC(F)(F)F>>C[Si](C)(C)CCOCn1cc(C(=O)N[C@@H](C(=O)N2CC(C#N)C2)C2CC2)c2nc(-c3cc4nccc(OCC(F)(F)F)c4s3)cnc21 -US20060183780A1,1,CCCCCc1ccc(C(=O)Cl)cc1.CN(C)c1ccc(NC(=O)c2cc[nH]n2)cc1>>CCCCCc1ccc(C(=O)n2ccc(C(=O)Nc3ccc(N(C)C)cc3)n2)cc1 -US20150252011A1,9,NC1=N[C@](CF)(c2cc(Br)ccc2F)[C@H]2C[C@H]2O1.[NH4+]>>NC1=N[C@](CF)(c2cc(N)ccc2F)[C@H]2C[C@H]2O1 -US20040063735A1,7,O=C(O)c1ccc([N+](=O)[O-])c([N+](=O)[O-])c1>>O=[N+]([O-])c1ccc(CO)cc1[N+](=O)[O-] -US04416880,3,CCOC(=O)CC(=O)CCl.O=Cc1ccccc1C(F)(F)F>>CCOC(=O)C(=Cc1ccccc1C(F)(F)F)C(=O)CCl -US20140323504A1,1,Cn1cc(N)cn1.O=[N+]([O-])c1cccc(Cn2ncc3cnc(Cl)nc32)c1>>Cn1cc(Nc2ncc3cnn(Cc4cccc([N+](=O)[O-])c4)c3n2)cn1 -US20090124613A1,1,O=C1NC(=O)c2ccccc21.OCCC1(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)OCc2ccccc21>>O=C1c2ccccc2C(=O)N1CCC1(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)OCc2ccccc21 -US04150140,2,CCOC(=O)C(=O)OCC.Nc1nc2ccccc2s1>>CCOC(=O)C(=O)Nc1nc2ccccc2s1 -US08664216B2,6,O=C1OC2(CCN(Cc3ccccc3)CC2)c2ccc(F)cc21>>O=C1OC2(CCNCC2)c2ccc(F)cc21 -US20130040930A1,1,CN1CCNC1=O.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)nc2)CC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CCN(C)C3=O)nc2)CC1 -US20100120784A1,1,Fc1cc(Cl)ccc1Br.O[C@H]1CC[C@H](O)CC1>>OC1CCC(Oc2cc(Cl)ccc2Br)CC1 -US20090170911A1,10,Cc1ccc(-c2nocc2NC(=O)OC(C)c2ccccc2Cl)cc1.O=C1CCC(=O)N1Br>>CC(OC(=O)Nc1conc1-c1ccc(CBr)cc1)c1ccccc1Cl -US20100286117A1,6,CCCCc1nocc1COc1ccc(C(=O)OC)cn1>>CCCCc1nocc1COc1ccc(C(=O)O)cn1 -US08853412B2,1,CC[S-].O=C1NCC[C@H]1Oc1ccc(Br)nc1>>CCSc1ccc(O[C@@H]2CCNC2=O)cn1 -US09107916B2,1,N#Cc1ccnc(-n2nccc2O)c1.OCc1ccc(Cl)cc1OCc1ccccc1>>N#Cc1ccnc(-n2nccc2OCc2ccc(Cl)cc2OCc2ccccc2)c1 -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)c(Cl)c3)c2cc1OC.O=C(N=C=S)c1ccccc1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccccc4)c(Cl)c3)c2cc1OC -US20090012308A1,1,BrCc1ccc2ccccc2c1.O=S([O-])c1ccccc1>>O=S(=O)(Cc1ccc2ccccc2c1)c1ccccc1 -US04550104,1,CC(C)(C)OC(=O)NC1CCNC1.O=C(O)c1c2n(c3cc(Cl)c(F)cc3c1=O)CCS2>>CC(C)(C)OC(=O)NC1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)c2n3CCS2)C1 -US04336380,2,C=CCN(CC=C)c1nc(N)n2oc(=O)nc2n1.O=C(Cl)c1ccc(Cl)cc1Cl>>C=CCN(CC=C)c1nc(NC(=O)c2ccc(Cl)cc2Cl)n2oc(=O)nc2n1 -US20140323464A1,2,CNCc1cccc(Nc2ncc3cc(-c4ccccc4Cl)c(=O)n(C)c3n2)c1.N#CC(=CC1CC1)C(=O)O>>CN(Cc1cccc(Nc2ncc3cc(-c4ccccc4Cl)c(=O)n(C)c3n2)c1)C(=O)C(C#N)=CC1CC1 -US08957070B2,7,CCN(c1ccc(C)c2cc(-c3ncc(C=O)s3)[nH]c12)S(=O)(=O)c1cccs1>>CCN(c1ccc(C)c2cc(-c3ncc(CO)s3)[nH]c12)S(=O)(=O)c1cccs1 -US05319099,4,NC(N)=O.O=C(Cl)C(Br)CCBr>>NC(=O)N1CCC(Br)C1=O -US20150266867A1,1,CC(C)(C)OC(=O)NCC=O.CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)N[C@@H]2C(=O)N[C@@H]2CNCCN)cs1>>CC(C)(C)OC(=O)NCCNCCNC[C@H]1NC(=O)[C@H]1NC(=O)/C(=N\OC(C)(C)C(=O)OC(C)(C)C)c1csc(NC(=O)OC(C)(C)C)n1 -US20090324581A1,6,CC(C)(C)OC(=O)N1CCc2cc(OCc3ccc(C4CCCCC4)c(C#N)c3)ccc21>>N#Cc1cc(COc2ccc3c(c2)CCN3)ccc1C1CCCCC1 -US20110245221A1,2,CC(=O)Cl.CCNC(=O)c1noc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)c1N>>CCNC(=O)c1noc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)c1NC(C)=O -US06369034B1,1,COC(=O)CBr.C[C@H](N)c1ccccc1>>COC(=O)CN[C@@H](C)c1ccccc1 -US05185341,2,Nc1c[nH]c(=O)[nH]c1=O.O=C(O)COc1ccc(Cl)cc1>>O=C(COc1ccc(Cl)cc1)Nc1c[nH]c(=O)[nH]c1=O -US06956121B2,9,N.O=C(Cl)OCC(Cl)(Cl)Cl>>NC(=O)OCC(Cl)(Cl)Cl -US05527792,4,CCOC(=O)CC(=O)CCl.NC(=S)c1c(O)cccc1O>>CCOC(=O)Cc1csc(-c2c(O)cccc2O)n1 -US05393755,1,Cc1nc2c([nH]1)C(=O)N(C)C1=N[C@@H]3CCC[C@@H]3N12.ClCc1ccncc1>>Cc1nc2c(n1Cc1ccncc1)C(=O)N(C)C1=N[C@@H]3CCC[C@@H]3N12 -US20040110746A1,1,CCCCN1CCN(C(=O)c2ccc(C=O)cc2)CC1.CNC>>CCCCN1CCN(C(=O)c2ccc(CN(C)C)cc2)CC1 -US05166214,7,CCCCCCCNC(=O)CC(C)(C)CCO>>CCCCCCCNCCC(C)(C)CCO -US06720321B2,2,Nc1ccc(OCCN2CCOCC2)c2ccccc12.O=C=N[C@@H]1C[C@H]1c1ccccc1>>O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)NC1CC1c1ccccc1 -US20100197924A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(N)c1cc(C(=O)O)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)NC(C)(C)c1cc(C(=O)O)cc(C(F)(F)F)c1 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)nc3)c(F)c2)OC1(C)C.N#Cc1ccc(Oc2ccccc2Br)nc1>>N#Cc1ccc(Oc2ccccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)nc1 -US20120149721A1,2,CCC(=O)Cl.Cc1cc(-c2ncnc3c(C(=O)N[C@@H]4CC[C@@H](N)CC4)c(C)[nH]c23)c(OCC2CC2)cc1F>>CCC(=O)N[C@@H]1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4cc(C)c(F)cc4OCC4CC4)ncnc23)CC1 -US07691883B2,1,CSCCO.O=Cc1cccc(O)c1>>CSCCOc1cccc(C=O)c1 -US06608070B1,3,COC(=O)Cc1c(C(=O)c2cccc(Br)c2)[nH]c2cc(Cl)ccc12.OB(O)c1ccco1>>COC(=O)Cc1c(C(=O)c2cccc(-c3ccco3)c2)[nH]c2cc(Cl)ccc12 -US08367843B2,2,COc1c(C#N)cc(C(=O)Cl)cc1C(C)C.c1ccc2c(c1)NCS2>>COc1c(C#N)cc(C(=O)N2CSc3ccccc32)cc1C(C)C -US20080262050A1,2,CNC.COc1cccc(OC)c1C(=O)Cl>>COc1cccc(OC)c1C(=O)N(C)C -US05140031,2,CCC(C)(C)N=C=S.N#CN>>CCC(C)(C)NC(=S)NC#N -US04335122,9,ClC1c2ccccc2COc2ccccc21.N#C[Cu]>>N#CC1c2ccccc2COc2ccccc21 -US20110151258A1,1,COc1ccccc1O.ClCC1CO1>>COc1ccccc1OCC1CO1 -US20100063047A1,1,Cc1csc2ncnc(Br)c12.OCCc1ccc(Cl)cc1>>Cc1csc2ncnc(OCCc3ccc(Cl)cc3)c12 -US08193191B2,1,COc1ccc([C@@H](CCCNS(=O)(=O)c2cccs2)N2C(=O)c3cccc(N4CCNCC4)c3C2=O)cc1OC.O=Cc1ccoc1>>COc1ccc([C@@H](CCCNS(=O)(=O)c2cccs2)N2C(=O)c3cccc(N4CCN(Cc5ccoc5)CC4)c3C2=O)cc1OC -US20040171620A1,3,CC[Sn](CC)(CC)CC.COC(=O)c1nc2c(cc1Br)SCC(=O)N2>>CCc1cc2c(nc1C(=O)OC)NC(=O)CS2 -US20090182140A1,1,Clc1cc(Cl)n2nccc2n1.NCc1ccc(Cl)cc1Cl>>Clc1ccc(CNc2cc(Cl)nc3ccnn23)c(Cl)c1 -US05763465,1,O=C(O)CCBr.SCCOCCc1ccccc1>>O=C(O)CCSCCOCCc1ccccc1 -US20130053382A1,3,CCCC[Sn](CCCC)(CCCC)c1cc(C(F)(F)F)nn1C1CCCCO1.COC(=O)c1csc(Br)n1>>COC(=O)c1csc(-c2cc(C(F)(F)F)nn2C2CCCCO2)n1 -US20070105855A1,1,CCOC(=O)C=O.COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c1oc1ccc(N)cc12>>CCOC(=O)CNc1ccc2oc3c(OC)ccc(C(=O)Nc4c(Cl)cncc4Cl)c3c2c1 -US20070259881A1,7,C=CCNc1c([N+](=O)[O-])c(Cl)nc2ccccc12>>C=CCNc1c(N)c(Cl)nc2ccccc12 -US20040204584A1,2,COCCOCc1cc(C(=O)O)ccn1.COc1ccc(C2COCCO2)c2sc(N)nc12>>COCCOCc1cc(C(=O)Nc2nc3c(OC)ccc(C4COCCO4)c3s2)ccn1 -US05162325,10,Cc1ccc(-c2ccncc2C#N)cc1.O=C1CCC(=O)N1Br>>N#Cc1cnccc1-c1ccc(CBr)cc1 -US20090143354A1,2,CS(=O)(=O)Cl.O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(N3CC[C@H](O)C3)ccc12>>CS(=O)(=O)O[C@H]1CCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)C1 -US04284644,2,CN=C=S.Nc1ccc2c(c1)C(=O)C1(CC1)O2>>CNC(=S)Nc1ccc2c(c1)C(=O)C1(CC1)O2 -US20130317024A1,3,CC(C)n1c(Br)cc2c1C(c1ccc(Cl)cc1)N([C@@H]1CC[C@@H](O)CC1)C2=O.COc1ccccc1B(O)O>>COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@@H]1CC[C@@H](O)CC1)C2=O -US20140371199A1,3,CN1CCN(S(=O)(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.N#Cc1ccc(-c2cnc3cnc(Br)cn23)cc1>>CN1CCN(S(=O)(=O)c2ccc(-c3cn4c(-c5ccc(C#N)cc5)cnc4cn3)cc2)CC1 -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(OC3CCCCO3)cc(F)c21>>CCOC(=O)CC1OB(O)c2cc(O)cc(F)c21 -US08329729B2,2,Nc1cnccn1.O=C(Br)CBr>>O=C(CBr)Nc1cnccn1 -US20140058098A1,2,C1COCCN1.O=C(O)c1ccc2c(c1)-c1nc(-c3ncnn3CC(F)(F)F)cn1CCO2>>O=C(c1ccc2c(c1)-c1nc(-c3ncnn3CC(F)(F)F)cn1CCO2)N1CCOCC1 -US08101775B2,1,C1CCNC1.CCOC(=O)c1cnc(Cl)c(Cl)c1>>CCOC(=O)c1cnc(N2CCCC2)c(Cl)c1 -US20060040999A1,3,COc1cc(F)c(C(C)C)cc1B(O)O.O=C1OC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1Cc1cc(C(F)(F)F)ccc1I>>COc1cc(F)c(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN1CC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC1=O -US08188101B2,1,CC(=O)N1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(OS(=O)(=O)C(F)(F)F)c2C1.c1ccc2c(c1)CCN2>>CC(=O)N1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(N3CCc4ccccc43)c2C1 -US20100120864A1,7,NC(C(=O)O)c1ccc(F)cc1C(F)(F)F>>NC(CO)c1ccc(F)cc1C(F)(F)F -US08486939B2,1,COc1cccc2[nH]c(C(F)F)nc12.O=[N+]([O-])c1c(Nc2cccnc2)nc(Cl)nc1N1CCOCC1>>COc1cccc2c1nc(C(F)F)n2-c1nc(Nc2cccnc2)c([N+](=O)[O-])c(N2CCOCC2)n1 -US20150246915A1,1,COC(=O)CBr.c1cc(-c2cn[nH]c2)n2nc(Nc3ccc(OCCN4CCCC4)cc3)nc2c1>>COC(=O)Cn1cc(-c2cccc3nc(Nc4ccc(OCCN5CCCC5)cc4)nn23)cn1 -US20150148332A1,3,CCn1nc(N2CCCC2)nc1C=O.Cc1ncc(C)n2nc(C[P+](c3ccccc3)(c3ccccc3)c3ccccc3)nc12>>CCn1nc(N2CCCC2)nc1C=Cc1nc2c(C)ncc(C)n2n1 -US20090012134A1,7,O=C(O)c1cc(I)ccc1O>>OCc1cc(I)ccc1O -US08765730B2,9,Cc1cc(C(=O)C[C@@H](c2ccccc2)c2ccc(Cl)cc2C)ccn1.NO>>Cc1cc(C(C[C@@H](c2ccccc2)c2ccc(Cl)cc2C)=NO)ccn1 -US05268481,7,COc1ccc(CCN2CC3C[Se]CC(C2)C3=O)cc1>>COc1ccc(CCN2CC3C[Se]CC(C3)C2)cc1 -US20110319378A1,1,C1COCCN1.CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CC=O)(CCO[Si](C(C)C)(C(C)C)C(C)C)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@](CCO[Si](C(C)C)(C(C)C)C(C)C)(CCN2CCOCC2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US20140296230A1,3,CN1C(=O)Nc2ccc(Br)cc2C1(C)c1ccccc1.Cc1noc(C)c1B(O)O>>Cc1noc(C)c1-c1ccc2c(c1)C(C)(c1ccccc1)N(C)C(=O)N2 -US20140357858A1,2,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=C(Cl)c1ccncc1>>O=C1CC(=O)N(c2ccc(NC(=O)c3ccncc3)cc2)c2ccc3ccccc3c2N1 -US20060252807A1,3,C#CC1CCN(C(=O)OC(C)(C)C)CC1.CCOC(=O)c1coc(Cl)n1>>CCOC(=O)c1coc(C#CC2CCN(C(=O)OC(C)(C)C)CC2)n1 -US20100063038A1,2,CC(C)(C)OC(=O)N1CCOC(C(=O)O)C1.CNOC>>CON(C)C(=O)C1CN(C(=O)OC(C)(C)C)CCO1 -US20120245136A1,1,CC(C)O.COc1cc(C(=O)N2CCC3(CC2)Oc2ccccc2C(O)C3C)ccc1OC(C)C>>COc1cc(C(=O)N2CCC3(CC2)Oc2ccccc2C(OC(C)C)C3C)ccc1OC(C)C -US20110294829A1,3,C#CCCCC.O=C1c2ccccc2C(=O)N1OCc1csc(Br)n1>>CCCCC#Cc1nc(CON2C(=O)c3ccccc3C2=O)cs1 -US20090221555A1,1,CC(=O)N[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl.CCN1CCc2ccc(N)cc2CC1>>CCN1CCc2ccc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NC(C)=O)n3)cc2CC1 -US20100048606A1,6,C=Cc1ccc2n(c1=O)CC1CC2CN(C(=O)OC(C)(C)C)C1>>C=Cc1ccc2n(c1=O)CC1CNCC2C1 -US20040224959A1,2,CCO.COc1ccc(C(=O)O)cc1N>>CCOC(=O)c1ccc(OC)c(N)c1 -US07935815B2,2,CC(C)(C)OC(=O)NN.O=C(O)C(CCCCl)C1CC1>>CC(C)(C)OC(=O)NNC(=O)C(CCCCl)C1CC1 -US03948942,4,Cc1cc(C)c(N)c(C)c1.O=C1C=C(Cl)C(=O)O1>>Cc1cc(C)c(N2C(=O)C=C(Cl)C2=O)c(C)c1 -US20100152160A1,2,COc1cc2c(cc1Cl)N(C(=O)OC(C)(C)C)CC(C(=O)O)O2.N#CC1(C(O)c2ccc(F)cc2)CCNCC1>>COc1cc2c(cc1Cl)N(C(=O)OC(C)(C)C)CC(C(=O)N1CCC(C#N)(C(O)c3ccc(F)cc3)CC1)O2 -US06872833B2,2,COc1ccc(C2COCCO2)c2sc(N)nc12.O=C(O)c1ccnc(COCC2CC2)c1>>COc1ccc(C2COCCO2)c2sc(NC(=O)c3ccnc(COCC4CC4)c3)nc12 -US06962941B2,2,CC(C)(C)OC(=O)NCc1ccc(CCC(=O)O)cc1.COC(=O)[C@@H]1C[C@H](N=[N+]=[N-])CN1>>COC(=O)[C@@H]1CC(N=[N+]=[N-])CN1C(=O)CCc1ccc(CNC(=O)OC(C)(C)C)cc1 -US20110213113A1,1,FC(F)(F)C(CCCCI)CC(F)(C(F)(F)F)C(F)(F)F.N#C[S-]>>N#CSCCCCC(CC(F)(C(F)(F)F)C(F)(F)F)C(F)(F)F -US20090203705A1,3,Nc1ccc(Cl)nn1.OB(O)c1cc(F)cc(F)c1>>Nc1ccc(-c2cc(F)cc(F)c2)nn1 -US20050261331A1,6,COc1cccc(-c2c(-c3ccccc3)[nH]c3ncc(Br)cc23)c1>>Oc1cccc(-c2c(-c3ccccc3)[nH]c3ncc(Br)cc23)c1 -US20110166169A1,6,CC(C)(C)OC(=O)c1ccc(-n2c3ccccc3c3c(-c4ccc(C#N)nc4)cccc32)cc1NCCF>>N#Cc1ccc(-c2cccc3c2c2ccccc2n3-c2ccc(C(=O)O)c(NCCF)c2)cn1 -US04283532,1,CN(Cc1ccccc1)C(=O)Cc1ccccc1Br.Nc1c(Cl)cccc1Cl>>CN(Cc1ccccc1)C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCc2ccccc2)cc1)Nc1ccccc1>>CCOC(=O)C(Cc1ccc(O)cc1)Nc1ccccc1 -US20080119488A1,2,CC1(C)OCC(CN)O1.Cc1ccc(Cn2c(-c3ccc(Oc4ccc5[nH]c(C(=O)O)cc5c4)cc3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1>>Cc1ccc(Cn2c(-c3ccc(Oc4ccc5[nH]c(C(=O)NCC6COC(C)(C)O6)cc5c4)cc3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1 -US20120157460A1,2,CC(C)(C)OC(=O)NCc1nc2cc(Br)ccc2n1CCO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NCc1nc2cc(Br)ccc2n1CCOS(C)(=O)=O -US08227500B2,6,CCOC(=O)c1ccc(-n2cc(C#N)c(-c3ccccc3OCCOC)c2)cc1O>>COCCOc1ccccc1-c1cn(-c2ccc(C(=O)O)c(O)c2)cc1C#N -US20080114051A1,8,CCCCC1(CO)CCC1>>CCCCC1(C=O)CCC1 -US20150105388A1,8,O=C(OO)c1cccc(Cl)c1.O=C(c1cc(-c2cc(F)cc(OC(F)(F)F)c2)n(-c2cccnc2)n1)N1CCSC1>>O=C(c1cc(-c2cc(F)cc(OC(F)(F)F)c2)n(-c2cccnc2)n1)N1CCS(=O)C1 -US08153644B2,6,COC(=O)C1CCC(c2noc(=O)[nH]2)CC1>>O=C(O)C1CCC(c2noc(=O)[nH]2)CC1 -US20120122942A1,1,CCCCCCc1cc2ccccc2[nH]1.CI>>CCCCCCc1cc2ccccc2n1C -US20140194408A1,7,O=[N+]([O-])c1cn(C2COC2)cn1>>Nc1cn(C2COC2)cn1 -US06251910B1,7,CCCSc1nc(Cl)c([N+](=O)[O-])c(N[C@H]2C=C[C@@H](O)C2)n1>>CCCSc1nc(Cl)c(N)c(N[C@H]2C=C[C@@H](O)C2)n1 -US20080027050A1,9,CCOC(=O)c1nc2scc(CBr)c2c(=O)[nH]1.[N-]=[N+]=[N-]>>CCOC(=O)c1nc2scc(CN=[N+]=[N-])c2c(=O)[nH]1 -US20150152065A1,1,CC(C)(C)OC(=O)NC1(C(=O)O)CCNCC1.OB(O)c1cnc(Cl)nc1>>CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncc(B(O)O)cn2)CC1 -US20130225548A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cc(C4CC4)cc(Nc4cc(C#N)ccn4)n3)cn2)CC1>>N#Cc1ccnc(Nc2cc(C3CC3)cc(-c3ccc(N4CCNCC4)nc3)n2)c1 -US08212045B2,1,N#Cc1ncc(Br)cc1Oc1ccc(F)cc1.Sc1ccccn1>>N#Cc1ncc(Sc2ccccn2)cc1Oc1ccc(F)cc1 -US09127164B2,7,CC(C)(C)OC(=O)C=Cc1ccc2nc3ccccc3c(N)c2c1>>CC(C)(C)OC(=O)CCc1ccc2nc3ccccc3c(N)c2c1 -US08853390B2,1,Brc1ccc([C@H]2C[C@@H]2CN2CCOCC2)cc1.O=c1cccn[nH]1>>O=c1cccnn1-c1ccc([C@H]2C[C@@H]2CN2CCOCC2)cc1 -US20100317582A1,1,C[C@@H](N)c1cccc2ccccc12.O=C1CCCC(c2ccccn2)C1>>C[C@@H](NC1CCCC(c2ccccn2)C1)c1cccc2ccccc12 -US20130040983A1,1,CC[S-].O=C(O)c1cc(-c2[nH]c(-c3ccccc3)nc2-c2ccncc2)ccc1F>>CCSc1ccc(-c2[nH]c(-c3ccccc3)nc2-c2ccncc2)cc1C(=O)O -US04460770,2,Cc1ccc(S(=O)(=O)Cl)cc1.N#CC1CCC(CO)CC1>>Cc1ccc(S(=O)(=O)OC[C@@H]2CC[C@@H](C#N)CC2)cc1 -US20090062530A1,1,O=Cc1ccc(F)c(Br)c1.c1c[nH]cn1>>O=Cc1ccc(-n2ccnc2)c(Br)c1 -US20150175530A1,2,COC(=O)[C@@H](NC(=O)c1ccc(C#C/C=C/C(O)CO)cc1)C(C)(C)N.NO>>CC(C)(N)[C@H](NC(=O)c1ccc(C#C/C=C/C(O)CO)cc1)C(=O)NO -US20120208827A1,1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.O=[N+]([O-])c1cc(C(F)(F)F)ccc1F>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2ccc(C(F)(F)F)cc2[N+](=O)[O-])C1 -US20080292588A1,1,CCC(N)CC(=O)OC.O=Cc1ccc(F)cc1>>CCC(CC(=O)OC)NCc1ccc(F)cc1 -US04778790,1,CC(C)(C)OC(=O)CN1C[C@@H](c2cccs2)SC[C@H](N)C1=O.CCOC(=O)C(Br)CCCCCCCNC(=O)OC(C)(C)C>>CCOC(=O)[C@@H](CCCCCCCNC(=O)OC(C)(C)C)N[C@H]1CS[C@H](c2cccs2)CN(CC(=O)OC(C)(C)C)C1=O -US08173650B2,6,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3CCN(C(=O)OC(C)(C)C)CC3)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3CCNCC3)n(C)c2n1 -US08981089B2,6,CC(=O)N1CCC(N(C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)C(=O)c2ccccc2)CC1>>CC(=O)N1CCC(N(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)CC1 -US20140005172A1,6,CC(C)(C)OC(=O)N1CCOc2ccc(-c3cnc(N)c(S(N)(=O)=O)c3)cc2C1>>Nc1ncc(-c2ccc3c(c2)CNCCO3)cc1S(N)(=O)=O -US20020132007A1,2,CCCCCCCCCCCCO.N=C(N)NCCC[C@H](N)C(=O)O>>CCCCCCCCCCCCOC(=O)[C@@H](N)CCCNC(=N)N -US20110076291A1,2,O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2.OCC1CCNCC1>>O=C(c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2)N1CCC(CO)CC1 -US05739162,6,O=C(CNC(=O)OCc1ccccc1)Nc1ccccc1C(=O)c1ccccc1>>NCC(=O)Nc1ccccc1C(=O)c1ccccc1 -US20150057265A1,1,CC(C)(C)OC(=O)N[C@H]1CCCNC1.O=[N+]([O-])c1cnccc1Cl>>CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2[N+](=O)[O-])C1 -US20050182103A1,2,CN.O=C(Cl)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1>>CNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 -US20080269219A1,7,CCOC(=O)CCc1oc(Cl)nc1-c1ccc(Cl)cc1>>OCCCc1oc(Cl)nc1-c1ccc(Cl)cc1 -US08003649B2,1,C#Cc1cccc(C=O)c1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>C#Cc1cccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)c1 -US08501382B1,2,CC(C)(O)CCO.O=S(=O)(Cl)c1ccccc1C(F)(F)F>>CC(C)(O)CCOS(=O)(=O)c1ccccc1C(F)(F)F -US08299085B2,1,CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc2c1=O.OCCNCCO>>CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(N(CCO)CCO)cc2c1=O -US20150259367A1,9,NO.O=C1CC2(C1)C(=O)Nc1ccccc12>>O=C1Nc2ccccc2C12CC(=NO)C2 -US07524486B2,2,CCCCCCCCCCCCCCCCCCCCCCOCCCN.COC(=O)CCl>>CCCCCCCCCCCCCCCCCCCCCCOCCCNC(=O)CCl -US20110166137A1,1,COc1ccc2cc(-c3ccnc(NCCCN(C)C)n3)cc(N3CCNCC3)c2c1.Clc1ncnc2[nH]nc(Br)c12>>COc1ccc2cc(-c3ccnc(NCCCN(C)C)n3)cc(N3CCN(c4ncnc5[nH]nc(Br)c45)CC3)c2c1 -US20120046293A1,7,CCCOC(=O)c1cc(/C=C/COC)nc2ccccc12>>CCCOC(=O)c1cc(CCCOC)nc2ccccc12 -US08324221B2,6,CC(C)NCc1c(Cl)ccc2c1C1(CCN(Cc3ccccc3)CC1)CN2c1ncnc2c1[C@H](C)C[C@H]2OC(=O)c1ccc([N+](=O)[O-])cc1>>CC(C)NCc1c(Cl)ccc2c1C1(CCNCC1)CN2c1ncnc2c1[C@H](C)C[C@H]2OC(=O)c1ccc([N+](=O)[O-])cc1 -US20100197665A1,7,CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(S(=O)(=O)c5ccccc5)cc34)c([N+](=O)[O-])c2)CC1>>CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(S(=O)(=O)c5ccccc5)cc34)c(N)c2)CC1 -US20110190227A1,2,CCOC(=O)Cc1ccc(OC)c(Oc2ccc(N)cc2CSC(C)(C)C)c1.O=C(Cl)c1ccccc1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(NC(=O)c3ccccc3)cc2CSC(C)(C)C)c1 -US04560685,1,C1CNCCN1.CN(C)c1nc2nc(Cl)nc(N(C)C)c2nc1Cl>>CN(C)c1nc2nc(N3CCNCC3)nc(N(C)C)c2nc1Cl -US04138579,1,C#CCBr.COc1cc(C(=O)O)cc(Br)c1O>>C#CCOC(=O)c1cc(Br)c(O)c(OC)c1 -US20150018547A1,1,COC(=O)CC(=O)C(C)Br.COc1cc(S)cc(Cl)c1>>COC(=O)CC(=O)C(C)Sc1cc(Cl)cc(OC)c1 -US20080139631A1,1,BrCC1CC1.O=[N+]([O-])c1ccc2[nH]ncc2c1>>O=[N+]([O-])c1ccc2c(cnn2CC2CC2)c1 -US07829584B2,1,CC(C)(C)OC(=O)Nc1noc2cc(CNC(=O)Cc3c(C#N)ccc(Cl)[n+]3[O-])ccc12.NCC(F)(F)c1ccccn1>>CC(C)(C)OC(=O)Nc1noc2cc(CNC(=O)Cc3c(C#N)ccc(NCC(F)(F)c4ccccn4)[n+]3[O-])ccc12 -US05861401,2,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.COc1nc(Br)cnc1N>>COc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(N(C)C)cccc12 -US07576122B2,2,CCCCNCCCC.COc1ccc2oc(C(=O)c3ccccc3)c(CC(=O)O)c2c1>>CCCCN(CCCC)C(=O)Cc1c(C(=O)c2ccccc2)oc2ccc(OC)cc12 -US08895729B2,6,C[C@H](O)C(=O)N1CCN(Cc2ccccc2)CC1>>C[C@H](O)C(=O)N1CCNCC1 -US20060135525A1,1,CC(C)(C)OC(=O)c1ccc(F)cc1.CC(C)(S)CN>>CC(C)(C)OC(=O)c1ccc(SC(C)(C)CN)cc1 -US20080070912A1,3,CC(C)c1nn2ccccc2c1I.OB(O)c1ccncc1>>CC(C)c1nn2ccccc2c1-c1ccncc1 -US08288433B2,6,COC(=O)c1ccccc1CN(C(=O)OC(C)(C)C)S(=O)(=O)c1cc(C(=O)NN2c3ccccc3CC2C)ccc1Cl>>CC1Cc2ccccc2N1NC(=O)c1ccc(Cl)c(S(=O)(=O)N(Cc2ccccc2C(=O)O)C(=O)OC(C)(C)C)c1 -US20080153813A1,5,Brc1ccc2[nH]ncc2c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1ncc2cc(Br)ccc21 -US20090181942A1,1,C=C(c1cc(Cl)ccc1N)c1cccc(OC)c1OC.COc1ccc(C=O)c(OC)c1>>C=C(c1cc(Cl)ccc1NCc1ccc(OC)cc1OC)c1cccc(OC)c1OC -US20140356385A1,6,CC(=O)SCCOCCOCCOCCOCCC(=O)NCCCCCNC(=O)OC(C)(C)C>>CC(=O)SCCOCCOCCOCCOCCC(=O)NCCCCCN -US20090275581A1,6,COCCCO[C@@H](c1cccc(F)c1-c1cccc(C)c1)[C@H]1CN(C(=O)OC(C)(C)C)CCO1>>COCCCO[C@@H](c1cccc(F)c1-c1cccc(C)c1)[C@H]1CNCCO1 -US08173650B2,1,Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(Cl)nc21.Nc1cccc(F)c1[N+](=O)[O-]>>Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(Nc3cccc(F)c3[N+](=O)[O-])nc21 -US20060084643A1,1,N#Cc1c(N)sc2ccccc12.O=[N+]([O-])c1cc(C(F)(F)F)ccc1F>>N#Cc1c(Nc2ccc(C(F)(F)F)cc2[N+](=O)[O-])sc2ccccc12 -US20110124642A1,2,COc1ccc(-c2nn(N)c(=O)c3ccccc23)cc1.O=C(Cl)Cc1cc(F)cc(F)c1>>COc1ccc(-c2nn(NC(=O)Cc3cc(F)cc(F)c3)c(=O)c3ccccc23)cc1 -US20040235897A1,1,Brc1cccc(C2OCCO2)c1.NC1CCN(Cc2ccccc2)CC1>>c1ccc(CN2CCC(Nc3cccc(C4OCCO4)c3)CC2)cc1 -US20080045521A1,4,COC(=O)[C@H](Cc1ccc(CCCC(C)=O)cn1)NC(=O)OC(C)(C)C.Nc1ncccc1C=O>>COC(=O)[C@H](Cc1ccc(CCCc2ccc3cccnc3n2)cn1)NC(=O)OC(C)(C)C -US20030149027A1,7,CC(C)(C)OC(=O)NCc1ccc(Nc2ccccc2[N+](=O)[O-])cc1>>CC(C)(C)OC(=O)NCc1ccc(Nc2ccccc2N)cc1 -US05700806,2,CS(=O)(=O)Cl.O=C(C(CO)c1ccccc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1>>CS(=O)(=O)OCC(C(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1)c1ccccc1 -US20020156081A1,1,Clc1ncc(Br)cn1.Oc1ccccc1>>Brc1cnc(Oc2ccccc2)nc1 -US08309581B2,1,BrCC1CCCCC1.COc1ccccc1-c1nc2cc(F)c(F)cc2[nH]1>>COc1ccccc1-c1nc2cc(F)c(F)cc2n1CC1CCCCC1 -US05177096,6,CCCCc1ncc(/C=C(\Cc2ccc(OC)cc2)c2nnn[nH]2)n1Cc1ccccc1Cl>>CCCCc1ncc(/C=C(\Cc2ccc(O)cc2)c2nnn[nH]2)n1Cc1ccccc1Cl -US20120101083A1,2,C[C@@H](O)[C@H](NC(=O)OC(C)(C)C)C(=O)O.Cc1c(-c2noc(-c3cnc(OC(C)C)c(C#N)c3)n2)ccc2c1CCNC2>>Cc1c(-c2noc(-c3cnc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)O)C2 -US20100035934A1,1,Cc1cc(C)[nH]n1.Fc1cccc(Nc2ccc(Cl)cc2)n1>>Cc1cc(C)n(-c2cccc(Nc3ccc(Cl)cc3)n2)n1 -US20130012703A1,3,C=C[Sn](CCCC)(CCCC)CCCC.Clc1nc(NCc2ccccc2)c2scc(Br)c2n1>>C=Cc1csc2c(NCc3ccccc3)nc(Cl)nc12 -US08871798B2,3,CN1C(=O)C2C(C1=O)C1CCCCN1C2/C=C/c1ccc(Br)cn1.OB(O)c1cccc(C(F)(F)F)c1>>CN1C(=O)C2C(C1=O)C1CCCCN1C2/C=C/c1ccc(-c2cccc(C(F)(F)F)c2)cn1 -US07388103B2,2,CCOC(=O)C1(CC(C)C)CCCC1O.O=C(Cl)c1ccccc1>>CCOC(=O)C1(CC(C)C)CCCC1OC(=O)c1ccccc1 -US20080009507A1,9,COc1nccc2nc(-c3ccc(C(C)(C)N=[N+]=[N-])cc3)c(-c3cccs3)cc12>>COc1nccc2nc(-c3ccc(C(C)(C)N)cc3)c(-c3cccs3)cc12 -US05658911,1,Fc1ccc2c(C3CCNCC3)nsc2c1.O=C1c2ccccc2C(=O)N1CCBr>>O=C1c2ccccc2C(=O)N1CCN1CCC(c2nsc3cc(F)ccc23)CC1 -US20110160207A1,6,COC(=O)c1sc(-c2ccc(Cl)cc2)cc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1cc(-c2ccc(Cl)cc2)sc1C(=O)O -US20140107109A1,9,CC1(C)C(N)=N[C@](C)(c2cc(Br)ccc2F)CS1(=O)=O>>CC1(C)C(N)=N[C@](C)(c2ccccc2F)CS1(=O)=O -US20070185075A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]2CNC[C@@H]21.Nc1nc(Cl)cc(Cl)n1>>CC(C)(C)OC(=O)N1CCC[C@@H]2CN(c3cc(Cl)nc(N)n3)C[C@@H]21 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.COc1ccc(C)cc1B(O)O>>CCCNC(=O)c1nnc2c(-c3cc(C)ccc3OC)cccc2c1N -US20120309966A1,2,COc1cc(B2OC(C)(C)C(C)(C)O2)c(F)cc1N.COc1cccc2c1cc(C(=O)O)n2C>>COc1cc(B2OC(C)(C)C(C)(C)O2)c(F)cc1NC(=O)c1cc2c(OC)cccc2n1C -US20090069282A1,3,Brc1cnc(OCCN2CCCC2)nc1.C#Cc1ccc(-c2ccc(Cl)cc2)cn1>>Clc1ccc(-c2ccc(C#Cc3cnc(OCCN4CCCC4)nc3)nc2)cc1 -US20110160243A1,6,CC(C)(C)OC(=O)CC1CCn2c1cc1cc(OCc3cc(C#N)cc(OC(F)(F)F)c3)ccc12>>N#Cc1cc(COc2ccc3c(c2)cc2n3CCC2CC(=O)O)cc(OC(F)(F)F)c1 -US04857539,6,COc1ccc(-c2cccs2)cc1>>Oc1ccc(-c2cccs2)cc1 -US20150087645A1,2,COc1ccc(N2CCN[C@@H](Cc3ccccc3)C2)cc1OC(C)C.O=C(O)Cc1cc[nH]c1>>COc1ccc(N2CCN(C(=O)Cc3cc[nH]c3)[C@@H](Cc3ccccc3)C2)cc1OC(C)C -US08293768B2,6,CCOC(=O)c1sc(N2CCN(Cc3ccncc3)C2=O)nc1C>>Cc1nc(N2CCN(Cc3ccncc3)C2=O)sc1C(=O)O -US20150158878A1,6,CCOC(=O)c1cnc(Nc2cc(OC)nc(OC)n2)s1>>COc1cc(Nc2ncc(C(=O)O)s2)nc(OC)n1 -US08569294B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC1CCNC1>>CC(C)(C)OC(=O)N1CCC(O)C1 -US04027028,1,CC(=O)Nc1ccc(OCCBr)cc1.CCC(=O)N(c1ccccc1)C1CCNCC1>>CCC(=O)N(c1ccccc1)C1CCN(CCOc2ccc(NC(C)=O)cc2)CC1 -US20130331378A1,9,COC(=O)c1ccc(C(O)c2c(-c3ccccc3)nn3c([Si](C)(C)C)c(OC)ccc23)o1>>COC(=O)c1ccc(Cc2c(-c3ccccc3)nn3c([Si](C)(C)C)c(OC)ccc23)o1 -US05814646,2,FC(F)(F)c1cc(N=C=S)ccc1Cl.Nc1ccc(Sc2ccc(-c3ccccc3)nn2)cc1>>FC(F)(F)c1cc(NC(=S)Nc2ccc(Sc3ccc(-c4ccccc4)nn3)cc2)ccc1Cl -US05216150,6,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)C(=O)O -US20100009956A1,6,CC(C)(C)OC(=O)NN(c1nc(C#N)ncc1Br)C1CCOCC1>>N#Cc1ncc(Br)c(N(N)C2CCOCC2)n1 -US20100105683A1,3,C[Mg+].O=Cc1cccnc1>>CC(O)c1cccnc1 -US06005000,1,BrCc1ccccc1.O=C1OC(CCO)C(O)=C1OCc1ccccc1>>O=C1OC(CCO)C(OCc2ccccc2)=C1OCc1ccccc1 -US09108936B2,2,CC(C)(C)[C@H](O)CCN.Cc1cc(N2CCOCC2)cc(C2CC2)c1C(=O)O>>Cc1cc(N2CCOCC2)cc(C2CC2)c1C(=O)NCC[C@@H](O)C(C)(C)C -US08129379B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Br)cc1F>>CC(C)(C)OC(=O)Nc1ccc(Br)cc1F -US08957070B2,2,C1COCCN1.CN(c1cccc2cc(-c3nccs3)[nH]c12)S(=O)(=O)c1ccsc1C(=O)O>>CN(c1cccc2cc(-c3nccs3)[nH]c12)S(=O)(=O)c1ccsc1C(=O)N1CCOCC1 -US04499277,9,Clc1cccc(C(Cl)(Cl)Cl)n1>>Clc1cccc(C(Cl)Cl)n1 -US07226926B2,3,CC1(C)OB(c2ccc(F)cc2C#N)OC1(C)C.Fc1cccnc1Cl>>N#Cc1cc(F)ccc1-c1ncccc1F -US07767669B2,7,COc1cccc(-c2cc(Nc3cccnc3)nc(CC(=O)N3CCOCC3)n2)c1>>COc1cccc(-c2cc(Nc3cccnc3)nc(CCN3CCOCC3)n2)c1 -US04000183,6,CCOC(=O)CCCOc1cc(C)ccc1C12CC3CC(CC(C3)C1)C2>>Cc1ccc(C23CC4CC(CC(C4)C2)C3)c(OCCCC(=O)O)c1 -US20040087568A1,6,CNc1nccc(C(C)Nc2ccccc2C(=O)Nc2ccc3c(c2)CN(C(=O)OC(C)(C)C)CC3(C)C)n1>>CNc1nccc(C(C)Nc2ccccc2C(=O)Nc2ccc3c(c2)CNCC3(C)C)n1 -US06821967B2,1,Clc1cccc2nc(N3CCNCC3)ccc12.O=C(NCC(F)(F)F)C1(CCCCBr)c2ccccc2Oc2ccccc21>>O=C(NCC(F)(F)F)C1(CCCCN2CCN(c3ccc4c(Cl)cccc4n3)CC2)c2ccccc2Oc2ccccc21 -US20110166152A1,6,CCOC(=O)c1ccc2nc(C#C[Si](C)(C)C)sc2c1>>C#Cc1nc2ccc(C(=O)OCC)cc2s1 -US04731358,4,BrCCCCCBr.Nc1cc2c(cn1)[nH]c1ccccc12>>c1ccc2c(c1)[nH]c1cnc(N3CCCCC3)cc12 -US20150175562A1,9,Cc1ccc(S(=O)(=O)C(NC=O)c2cc(C(C)(C)C)cc(C(C)(C)C)c2)cc1>>[C-]#[N+]C(c1cc(C(C)(C)C)cc(C(C)(C)C)c1)S(=O)(=O)c1ccc(C)cc1 -US20100210642A1,2,Cc1cc(CN)cc(C)n1.O=S(=O)(Cl)c1ccc(Br)s1>>Cc1cc(CNS(=O)(=O)c2ccc(Br)s2)cc(C)n1 -US20060211695A1,7,CN(C)CC(=O)c1c[nH]c2nccc(Oc3ccc([N+](=O)[O-])cc3F)c12>>CN(C)CC(=O)c1c[nH]c2nccc(Oc3ccc(N)cc3F)c12 -US20140094462A1,7,C[C@H]1COC(=O)[C@H](C)CC=CCCC(=O)N1>>C[C@H]1COC(=O)[C@H](C)CCCCCC(=O)N1 -US20130231336A1,7,O=C1CCN(c2cccc(-c3ccnc(Cl)n3)c2)CC1>>OC1CCN(c2cccc(-c3ccnc(Cl)n3)c2)CC1 -US05733910,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1c(Cl)cc(N)cc1Cl>>COc1c(Cl)cc(NC(=O)OC(C)(C)C)cc1Cl -US06248754B1,1,C=O.CCOc1ccc(C(=O)Nc2ccc3c(c2Cl)CNCC3)cc1Br>>CCOc1ccc(C(=O)Nc2ccc3c(c2Cl)CN(C)CC3)cc1Br -US20110076230A1,1,Cc1ccc2cc(-c3ccc(F)nc3)[nH]c2c1.c1nc[nH]n1>>Cc1ccc2cc(-c3ccc(-n4cncn4)nc3)[nH]c2c1 -US07968570B2,3,C#CCN(C)C.O=C1c2ccc(Br)cc2CN1Cc1ccc(Oc2ccccc2)cc1>>CN(C)CC#Cc1ccc2c(c1)CN(Cc1ccc(Oc3ccccc3)cc1)C2=O -US20090227579A1,6,CN(c1nc(C#N)nc(N(CCOCc2ccccc2)CCO[Si](C)(C)C(C)(C)C)c1N)C1CCCC1>>CN(c1nc(C#N)nc(N(CCO)CCOCc2ccccc2)c1N)C1CCCC1 -US07179823B1,1,CCOC(=O)c1c[nH]nc1-c1ccc(F)cc1.ClCc1ccc(OCc2ccccc2)cc1>>CCOC(=O)c1cn(Cc2ccc(OCc3ccccc3)cc2)nc1-c1ccc(F)cc1 -US20080221149A1,3,COc1ccc2oc(B(O)O)cc2c1.Nc1ccc(Br)nc1F>>COc1ccc2oc(-c3ccc(N)c(F)n3)cc2c1 -US20100144760A1,1,Cc1ccc(S(=O)(=O)N2C[C@@H]3C[C@@H]3C[C@H]2C=O)cc1.Nc1ccc(C(F)(F)F)cn1>>Cc1ccc(S(=O)(=O)N2C[C@@H]3C[C@@H]3C[C@H]2/C=N/c2ccc(C(F)(F)F)cn2)cc1 -US20110124875A1,2,CC(=O)NCc1cc(F)ccc1S(=O)(=O)Cl.NC1CC1>>CC(=O)NCc1cc(F)ccc1S(=O)(=O)NC1CC1 -US20150197498A1,7,COc1cc(-c2ccc(-c3nc4cc([N+](=O)[O-])ccc4o3)cc2)cc(OC)c1OC>>COc1cc(-c2ccc(-c3nc4cc(N)ccc4o3)cc2)cc(OC)c1OC -US09156837B2,3,CC(C)(C)n1ncc(-c2nc(CC(=O)NCC3CCOCC3)cs2)c1Br.COc1ccc(B(O)O)cc1>>COc1ccc(-c2c(-c3nc(CC(=O)NCC4CCOCC4)cs3)cnn2C(C)(C)C)cc1 -US20150266848A1,4,Clc1ccccc1/C=C/COCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>Clc1ccccc1C1OC1COCc1ccccc1 -US20070043048A1,7,N#CCCN1CCC(Nc2nccc(-c3cc4ccccc4s3)n2)CC1>>NCCCN1CCC(Nc2nccc(-c3cc4ccccc4s3)n2)CC1 -US20150252044A1,3,O=C(NCCO)c1ccc2cncc(Br)c2n1.OB(O)c1cccc(O)c1>>O=C(NCCO)c1ccc2cncc(-c3cccc(O)c3)c2n1 -US20090286801A1,6,CCOC(=O)c1cccc(N2CCN(CCC3CCN(C(=O)OC(C)(C)C)CC3)CC2)c1>>CC(C)(C)OC(=O)N1CCC(CCN2CCN(c3cccc(C(=O)O)c3)CC2)CC1 -US20090029963A1,2,C1CCN(C2CCNCC2)C1.Cc1nn(-c2cccc(Cl)c2)c(C)c1C(=O)O>>Cc1nn(-c2cccc(Cl)c2)c(C)c1C(=O)N1CCC(N2CCCC2)CC1 -US07943607B2,6,C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(Oc2ccc3c(ccn3C)c2)cc(C(=O)Nc2ccn(C)n2)c1>>C[C@@H](CO)Oc1cc(Oc2ccc3c(ccn3C)c2)cc(C(=O)Nc2ccn(C)n2)c1 -US20030225064A1,4,CC(N)=S.CSc1ccc(C(=O)C(Br)c2ccc(Br)cc2)cc1>>CSc1ccc(-c2nc(C)sc2-c2ccc(Br)cc2)cc1 -US04264608,2,CN=C=S.COc1cccnc1CCCCN>>CNC(=S)NCCCCc1ncccc1OC -US20100010045A1,1,C#CCBr.COCCOCCO>>C#CCOCCOCCOC -US20090149483A1,3,CN(C)C=O.Cn1c(=O)c2c(cc(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)n2Cc2ccccc2Cl)n(C)c1=O>>Cn1c(=O)c2c(c(C=O)c(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)n2Cc2ccccc2Cl)n(C)c1=O -US07138425B2,1,CCCN.O=[N+]([O-])c1ccc(F)c(-c2nc3ccc(F)cc3o2)c1>>CCCNc1ccc([N+](=O)[O-])cc1-c1nc2ccc(F)cc2o1 -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12.O=Cc1cc[nH]c1>>FC(F)(F)c1nnc2ccc(N3CCN(Cc4cc[nH]c4)CC3)nn12 -US08436035B2,1,CI.OCc1cncn1C1CSCc2ccccc21>>COCc1cncn1C1CSCc2ccccc21 -US20140051679A1,3,CN1CCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2Cl)CC1.O=C(N[C@H](CCO)c1ccccc1)c1ccc2[nH]nc(I)c2c1>>CN1CCC(Oc2ccc(-c3n[nH]c4ccc(C(=O)N[C@H](CCO)c5ccccc5)cc34)cc2Cl)CC1 -US08933085B2,2,C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CC(N5CCNCC5)C4)c3)ncnc21.O=C=NC(C(F)(F)F)C(F)(F)F>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CC(N5CCN(C(=O)NC(C(F)(F)F)C(F)(F)F)CC5)C4)c3)ncnc21 -US20080255232A1,1,COC(=O)c1ccc(Br)cc1.COc1c(N)ccc2ccccc12>>COC(=O)c1ccc(Nc2ccc3ccccc3c2OC)cc1 -US07518000B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cccc(-c2cc3[nH]nc(I)c3s2)c1>>COc1cccc(-c2cc3c(s2)c(I)nn3C(=O)OC(C)(C)C)c1 -US20090286974A1,6,COC(=O)Cc1cccc(OCCNCCC2CCN(c3nc4ccc(Cl)cc4s3)C2)c1>>O=C(O)Cc1cccc(OCCNCCC2CCN(c3nc4ccc(Cl)cc4s3)C2)c1 -US20090018133A1,1,NCCCNc1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2n1.O=Cc1ccccn1>>O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cccc2nc(NCCCNCc3ccccn3)ccc12 -US05908841,1,CI.Cc1ncccc1C(=O)Nc1cccnc1Cl>>Cc1ncccc1C(=O)N(C)c1cccnc1Cl -US07332529B2,7,CCCCCCCCCOc1cc(OCCCCCCCCC)cc(C(=O)OC)c1>>CCCCCCCCCOc1cc(CO)cc(OCCCCCCCCC)c1 -US03950339,1,COc1ccc(N)cc1.Cc1cc(Cl)nc(SCC#N)n1>>COc1ccc(Nc2cc(C)nc(SCC#N)n2)cc1 -US08293911B2,2,CC(C)(C)CC(=O)Cl.Cc1cc(Br)cc(C)c1N>>Cc1cc(Br)cc(C)c1NC(=O)CC(C)(C)C -US20110269740A1,2,CCOC(=O)C(=O)Cl.NC(=O)c1cccn1N>>CCOC(=O)C(=O)Nn1cccc1C(N)=O -US06858621B2,7,O=[N+]([O-])c1ccc2c(c1)NCCO2>>Nc1ccc2c(c1)NCCO2 -US20100120789A1,1,O=C(CBr)C12CC3CC(CC(C3)C1)C2.Oc1ccc(-c2ccccc2)cc1>>O=C(COc1ccc(-c2ccccc2)cc1)C12CC3CC(CC(C3)C1)C2 -US20050176800A1,3,C#C[Mg+].CCCCC1(C=O)CCC1>>C#CC(O)C1(CCCC)CCC1 -US20150065704A1,8,NC(=O)N1c2ccccc2CC(O)c2ccccc21>>NC(=O)N1c2ccccc2CC(=O)c2ccccc21 -US07226925B2,1,CN(C)CCOc1ccccc1OCCO.C[C@@H]1CNCCN1c1nccnc1Cl>>C[C@@H]1CNCCN1c1nccnc1OCCOc1ccccc1OCCN(C)C -US20050004154A1,3,BrCc1ccccc1Br.C=CC[Mg+]>>C=CCCc1ccccc1Br -US07709468B2,6,CCOC(=O)C(C)(C)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(C)nccn23)n1>>Cc1nccn2c(-c3ccnc(NCC(C)(C)C(=O)O)n3)c(-c3ccc(F)cc3)nc12 -US08940726B2,1,CCOC(=O)COc1cccc2c1NC(=O)CO2.CI>>CCOC(=O)COc1cccc2c1N(C)C(=O)CO2 -US08420640B2,1,Nc1cc(N2CCN(C(=O)c3ccccc3)CC2)ccc1OCc1ccccc1.OB(O)c1ccccc1>>O=C(c1ccccc1)N1CCN(c2ccc(OCc3ccccc3)c(Nc3ccccc3)c2)CC1 -US20130324576A1,4,CC(=O)CC(=O)C(F)(F)F.CNN>>Cc1cc(C(F)(F)F)nn1C -US20100249124A1,3,CC(c1ccc(Br)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.O=C(O)c1ccccc1B(O)O>>CC(c1ccc(-c2ccccc2C(=O)O)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F -US20100137338A1,2,N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O.O=C(O)c1ccc(Br)cn1>>O=C(N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O)c1ccc(Br)cn1 -US20060030709A1,2,CCOC(=O)CNCCNS(=O)(=O)c1nc2ccccc2s1.COc1ccc(COC(=O)Nc2nc3c(ncn3CC(=O)O)c(=O)[nH]2)cc1OC>>CCOC(=O)CN(CCNS(=O)(=O)c1nc2ccccc2s1)C(=O)Cn1cnc2c(=O)[nH]c(NC(=O)OCc3ccc(OC)c(OC)c3)nc21 -US08022206B2,2,C[C@@H](Oc1c(N)ncc2c(C3=CCNCC3)coc12)c1c(Cl)ccc(F)c1Cl.O=C=Nc1ccccc1F>>C[C@@H](Oc1c(N)ncc2c(C3=CCN(C(=O)Nc4ccccc4F)CC3)coc12)c1c(Cl)ccc(F)c1Cl -US20100249192A1,6,CCOC(=O)Cn1nnc(-c2nc(-c3ccc(Oc4cc(Br)ccc4Cl)cc3)no2)n1>>O=C(O)Cn1nnc(-c2nc(-c3ccc(Oc4cc(Br)ccc4Cl)cc3)no2)n1 -US20070185155A1,1,BrCCOC1CCCCO1.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCOC3CCCCO3)(CC1)CC2 -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccccc4)CC3)C(=O)C(C)(C)C2)cc1OC.Cc1[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc2c1C(=O)O>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccccc4)NC(=O)c4c(C)[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)C(C)(C)C2)cc1OC -US20140323486A1,1,C1COCCN1.O=[N+]([O-])c1ccc(CBr)cc1>>O=[N+]([O-])c1ccc(CN2CCOCC2)cc1 -US04891363,8,OCCCCCCCOC1CCCCO1>>O=CCCCCCCOC1CCCCO1 -US05134111,6,CCc1cccc2c(/C(C)=C/C(=O)O)cc(OC)c(OCOC)c12>>CCc1cccc2c(/C(C)=C/C(=O)O)cc(OC)c(O)c12 -US20130137577A1,6,CCOC(=O)c1nc2ccccc2n(-c2ccc3c(c2)OCCO3)c1=O>>O=C(O)c1nc2ccccc2n(-c2ccc3c(c2)OCCO3)c1=O -US05102890,2,CC(C)CCCC(=O)Cl.O=C1c2ccccc2C(O)N1c1ccc2ccc(Br)nc2n1>>CC(C)CCCC(=O)OC1c2ccccc2C(=O)N1c1ccc2ccc(Br)nc2n1 -US20060052315A1,1,CNCC(O)c1ccccc1.O=Cc1ccc(Br)cc1>>CN(Cc1ccc(Br)cc1)CC(O)c1ccccc1 -US08188098B2,1,CS(=O)(=O)c1ccc(O)cc1.Clc1ncnc2c1cnn2C1CCCCO1>>CS(=O)(=O)c1ccc(Oc2ncnc3c2cnn3C2CCCCO2)cc1 -US20120115869A1,4,CCC(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1cccc(C#N)c1.[N-]=[N+]=[N-]>>CCC(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1cccc(-c2nnn[nH]2)c1 -US20150266881A1,6,Cn1cc(NC(=O)c2cccc([C@@H]3C[C@H]3NC(=O)OC(C)(C)C)c2)cn1>>Cn1cc(NC(=O)c2cccc([C@@H]3C[C@H]3N)c2)cn1 -US20140142085A1,6,CCOC(=O)C(CC(C)C)n1ccc(C(F)(F)F)n1>>CC(C)CC(C(=O)O)n1ccc(C(F)(F)F)n1 -US20070197581A1,6,O=S(=O)(c1ccc(Cl)cc1)C12CCCN(CCCOCc3ccccc3)C1COc1c(F)ccc(F)c12>>O=S(=O)(c1ccc(Cl)cc1)C12CCCN(CCCO)C1COc1c(F)ccc(F)c12 -US06632816B1,2,CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](N)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1.O=C(O)c1ccncc1>>CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](NC(=O)c1ccncc1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1 -US20040192653A1,7,N#Cc1cc(F)ccc1Oc1ccc2c(CN3CCCC3)noc2c1>>NCc1cc(F)ccc1Oc1ccc2c(CN3CCCC3)noc2c1 -US07745641B2,2,CC(C)(C)OC(=O)n1c(-c2ccc(N)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)n1c(-c2ccc(NS(C)(=O)=O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21 -US06780878B2,7,O=C(Nc1ccc(Cl)cc1)c1cccnc1NCC1CCN(c2ccncc2)CC1>>Clc1ccc(NCc2cccnc2NCC2CCN(c3ccncc3)CC2)cc1 -US08202984B2,1,CCI.Oc1ccc2sc(Cc3cc(Br)ccc3Cl)cc2c1>>CCOc1ccc2sc(Cc3cc(Br)ccc3Cl)cc2c1 -US20110190263A1,7,CC(=O)c1ccncc1>>CC(O)c1ccncc1 -US20140023642A1,2,O=C(O)c1cccc(CCn2c(=O)[nH]c(=O)c3ccccc32)c1.c1cnc(N2CCNCC2)nc1>>O=C(c1cccc(CCn2c(=O)[nH]c(=O)c3ccccc32)c1)N1CCN(c2ncccn2)CC1 -US08148367B2,6,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)[C@H](CNC(=O)c2ccccc2)C1>>CC(C)(C)OC(=O)N1CCN[C@H](CNC(=O)c2ccccc2)C1 -US20110263494A1,3,C=C[Mg+].CC12Cn3cnc(-c4ccc(F)cc4)c3C=C1CCCC2=O>>C=CC1(O)CCCC2=Cc3c(-c4ccc(F)cc4)ncn3CC21C -US04343945,2,Nc1nc(C(Cl)(Cl)Cl)ns1.O=C(Cl)c1ccccc1F>>O=C(Nc1nc(C(Cl)(Cl)Cl)ns1)c1ccccc1F -US20090264482A1,1,ClCc1noc(-c2ccccc2)n1.N#Cc1ccc2[nH]ccc2c1C(F)(F)F>>N#Cc1ccc2c(ccn2Cc2noc(-c3ccccc3)n2)c1C(F)(F)F -US07199239B2,1,CCCCN.CCOC(=O)COc1ccc(C=O)cc1CC>>CCCCNCc1ccc(OCC(=O)OCC)c(CC)c1 -US20150284381A1,1,CC1C=C(c2ccnc(Cl)c2)CCC1.COC(=O)c1ccc2c(c1)CCCC2(O)c1ncc(-c2cc(C)cc(N)n2)s1>>COC(=O)c1ccc2c(c1)CCC[C@]2(O)c1ncc(-c2cc(C)cc(Nc3cc(C4=CC(C)CCC4)ccn3)n2)s1 -US20080103170A1,6,CC(C)(C)OC(=O)NCC(=O)c1cccnc1>>NCC(=O)c1cccnc1 -US07851473B2,1,CC(C)(C)OC(=O)N1CCNCC1.Fc1cccc(-c2csc(Br)n2)c1F>>CC(C)(C)OC(=O)N1CCN(c2nc(-c3cccc(F)c3F)cs2)CC1 -US05021478,2,CCCCCCCCON1C(C)(C)CC(N)CC1(C)C.COC(=O)CCc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1>>CCCCCCCCON1C(C)(C)CC(NC(=O)CCc2cc(-n3nc4ccccc4n3)c(O)c(C(C)(C)C)c2)CC1(C)C -US04454335,2,COC(=O)Cc1ccccc1S(N)(=O)=O.O=C=Nc1nc(Cl)cc(Cl)n1>>COC(=O)Cc1ccccc1S(=O)(=O)NC(=O)Nc1nc(Cl)cc(Cl)n1 -US07943609B2,1,CN1CCNCC1.Nc1nc2ccccc2c2c1nc1n2[C@@H](CCl)COC1>>CN1CCN(C[C@H]2COCc3nc4c(N)nc5ccccc5c4n32)CC1 -US05756352,1,CCCCCCCCCCCCCCCCCCOCC(CBr)OCc1ccccc1.C[S-]>>CCCCCCCCCCCCCCCCCCOCC(CSC)OCc1ccccc1 -US20150257385A1,1,FC(F)(F)c1ccc(Cl)c(Cl)c1.N#CCc1ccc(O)cc1>>N#CCc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1 -US20100210592A1,1,CC(C)(C)OC(=O)NC(C(=O)c1ccc(O)cc1)c1ccc(Cl)cc1.OC1CCCC1>>CC(C)(C)OC(=O)NC(C(=O)c1ccc(OC2CCCC2)cc1)c1ccc(Cl)cc1 -US20110237784A1,2,Nc1cccc(O)c1.O=C(Cl)c1ccccc1>>O=C(Nc1cccc(O)c1)c1ccccc1 -US07148234B2,1,Nc1ccc(CCO)cc1.O=[N+]([O-])c1ccc(F)cc1F>>O=[N+]([O-])c1ccc(F)cc1Nc1ccc(CCO)cc1 -US20090076274A1,1,CI.Cc1ccc2c(N3CCN(CCc4ccc5c(c4)NC(=O)CO5)CC3C)cccc2n1>>Cc1ccc2c(N3CCN(CCc4ccc5c(c4)N(C)C(=O)CO5)CC3C)cccc2n1 -US20120184562A1,6,COC(=O)c1cc2cnc(NCC3COC(C)(C)O3)cc2[nH]c1=O>>CC1(C)OCC(CNc2cc3[nH]c(=O)c(C(=O)O)cc3cn2)O1 -US05434150,2,COC(=O)CCNC(=O)c1ccc2c(c1)nc(-c1ccc(C(=N)N)cc1)n2C.COC(=O)Cl>>COC(=O)CCNC(=O)c1ccc2c(c1)nc(-c1ccc(C(=N)NC(=O)OC)cc1)n2C -US07923561B2,1,NC1COc2ccccc21.O=S(=O)(Nc1cccc2nc(Cl)ccc12)c1cc(F)c(F)c(F)c1>>O=S(=O)(Nc1cccc2nc(NC3COc4ccccc43)ccc12)c1cc(F)c(F)c(F)c1 -US20120058988A1,4,CCOC(=O)C1CCCC(=O)C1.NNc1ccc(Br)cc1C(=O)O>>CCOC(=O)C1CCc2c([nH]c3c(C(=O)O)cc(Br)cc23)C1 -US06051712,9,BrC(Br)(Br)Br.C[Si](C)(C)CCOCOc1cc2ccccc2cc1CO>>C[Si](C)(C)CCOCOc1cc2ccccc2cc1CBr -US20150197493A1,1,COC(=O)c1ccc(OC2CC2)c(Br)c1.COc1ccc(CS)cc1>>COC(=O)c1ccc(OC2CC2)c(SCc2ccc(OC)cc2)c1 -US08552182B2,1,Oc1cc(Cl)nnc1Cl.Oc1cccc(C(F)(F)F)c1>>Oc1cc(Cl)nnc1Oc1cccc(C(F)(F)F)c1 -US20130217666A1,3,C#CC1(O)CCCC1.NC(=O)c1nc2c(s1)CCOc1cc(F)c(Br)cc1-2>>NC(=O)c1nc2c(s1)CCOc1cc(F)c(C#CC3(O)CCCC3)cc1-2 -US07612069B2,7,N#Cc1cc(N)cc(Cl)c1>>NCc1cc(N)cc(Cl)c1 -US04831041,1,O=C1NC(=O)c2ccccc21.O=[N+]([O-])c1ncccc1OCc1ccccc1CCl>>O=C1c2ccccc2C(=O)N1Cc1ccccc1COc1cccnc1[N+](=O)[O-] -US20110082129A1,2,N#CCc1ccccc1N.O=C(Cl)c1cccnc1>>N#CCc1ccccc1NC(=O)c1cccnc1 -US08598173B2,2,CCOC(=O)Nc1nc2ccc(F)cc2nc1OC.Clc1cccc(N2CCNCC2)c1>>COc1nc2cc(F)ccc2nc1NC(=O)N1CCN(c2cccc(Cl)c2)CC1 -US05665746,3,CN(C)C=O.COC(=O)c1cc(OC)cc(OC)c1C>>COC(=O)c1c(C)c(OC)cc(OC)c1C=O -US03979458,9,BrC(Br)(Br)Br.COC(CCCO)OC>>COC(CCCBr)OC -US07872018B2,3,CN(C)C=O.Fc1ccc(OCC(F)(F)F)c(Cl)c1>>O=Cc1c(F)ccc(OCC(F)(F)F)c1Cl -US20100119503A1,6,CC(C)(C)OC(=O)N1CCN(c2cncc(C(F)(F)F)c2)CC1>>FC(F)(F)c1cncc(N2CCNCC2)c1 -US08772510B2,2,C1CNC1.Cn1cc(-c2ccccc2)nc1CCNC(=O)c1c(C(=O)O)nnn1C>>Cn1cc(-c2ccccc2)nc1CCNC(=O)c1c(C(=O)N2CCC2)nnn1C -US20050009895A1,6,COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2NCC(=O)OCc2ccccc2)cc(OC)c1C>>COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2NCC(=O)O)cc(OC)c1C -US20080139564A1,7,CN(C)CCC(Oc1ccccc1)c1ccc(C#CCCN2CCCCC2)cc1>>CN(C)CCC(Oc1ccccc1)c1ccc(CCCCN2CCCCC2)cc1 -US20140303149A1,9,COc1cc2ccc(Br)cc2cc1NC(C)=O.[C-]#N>>COc1cc2ccc(C#N)cc2cc1NC(C)=O -US20040167155A1,1,COc1cccc(S(=O)(=O)NC(C)c2ccccc2-c2ccc(Cl)cc2F)c1>>COc1cccc(S(=O)(=O)N2c3cc(Cl)ccc3-c3ccccc3C2C)c1 -US20070299092A1,1,CNc1ccc(F)cc1.COCCOc1cc2ncnc(NC3=CC(=O)C(Cl)=CC3=O)c2cc1OC>>COCCOc1cc2ncnc(NC3=CC(=O)C(N(C)c4ccc(F)cc4)=CC3=O)c2cc1OC -US20110288067A1,3,CCCC[Sn](CCCC)(CCCC)c1cn(-c2cccc(Cl)c2)cn1.C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12)C(C)(C)C>>C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cn(-c4cccc(Cl)c4)cn3)nc12)C(C)(C)C -US09073890B2,1,Clc1ccc2nc(-c3cccnc3)nc(Cl)c2c1.Nc1ccccc1C(=O)NCC1CC1>>O=C(NCC1CC1)c1ccccc1Nc1nc(-c2cccnc2)nc2ccc(Cl)cc12 -US20060030709A1,2,O=C(O)Cn1ccc(NC(=O)OC(c2ccccc2)c2ccccc2)nc1=O.O=C1CNCCN1S(=O)(=O)c1nc2cc(Cl)ccc2s1>>O=C(Nc1ccn(CC(=O)N2CCN(S(=O)(=O)c3nc4cc(Cl)ccc4s3)C(=O)C2)c(=O)n1)OC(c1ccccc1)c1ccccc1 -US08557805B2,7,CS(=O)(=O)Cc1ccc(Oc2ccc([N+](=O)[O-])c(OC3CCOCC3)c2)cn1>>CS(=O)(=O)Cc1ccc(Oc2ccc(N)c(OC3CCOCC3)c2)cn1 -US20070179173A1,7,O=C1NC(=O)C(=Cc2ccc(O)c3c2CCC(=O)N3Cc2ccccc2)S1>>O=C1NC(=O)C(Cc2ccc(O)c3c2CCC(=O)N3Cc2ccccc2)S1 -US20090318425A1,3,CC(C)(CO)c1ccc(C(=O)Nc2nc3ccc(Br)nc3s2)cc1.Cc1cnccc1B(O)O>>Cc1cnccc1-c1ccc2nc(NC(=O)c3ccc(C(C)(C)CO)cc3)sc2n1 -US20130267571A1,2,CC(C)=CCC/C(C)=C/C(=O)O.CN>>CNC(=O)/C=C(\C)CCC=C(C)C -US20040198756A1,3,C#C[Si](C)(C)C.O=C1CCN(C(=O)OCc2ccccc2)CC1>>C[Si](C)(C)C#CC1(O)CCN(C(=O)OCc2ccccc2)CC1 -US20110028455A1,1,CCc1ncc(C#N)c(Cl)c1I.Cc1c(N)ccc2[nH]ccc12>>CCc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2C)c1I -US20070129416A1,2,CCOc1cc(C#N)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1.O=C(Cl)Cl>>CCOc1cc(C#N)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl -US20090099248A1,6,COC(=O)c1cc2c([nH]1)CCCC2Cc1ccccc1>>O=C(O)c1cc2c([nH]1)CCCC2Cc1ccccc1 -US08263606B2,1,Cc1ccc2c(c1)C1(COc3cc4c(cc31)OCCO4)C(=O)N2.FC(F)(F)c1cccnc1CCl>>Cc1ccc2c(c1)C1(COc3cc4c(cc31)OCCO4)C(=O)N2Cc1ncccc1C(F)(F)F -US06693109B2,6,CCOC(=O)CC1CCC2(CC1)CCN(CCC1CCNCC1)CC2>>O=C(O)CC1CCC2(CC1)CCN(CCC1CCNCC1)CC2 -US06169095A,2,CCN.Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(C(=O)O)cc4)c3Cl)c2n1>>CCNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1 -US20060063934A1,2,Nc1cc(-c2cn(C3=NNC(=O)CC3)nc2-c2ccccc2)ccn1.O=C(Cl)C1CC1>>O=C1CCC(n2cc(-c3ccnc(NC(=O)C4CC4)c3)c(-c3ccccc3)n2)=NN1 -US06777428B1,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=C(c1cccc([N+](=O)[O-])c1)C1CCNCC1>>O=C(c1cccc([N+](=O)[O-])c1)C1CCN(C(=O)C(F)(F)F)CC1 -US06518273B1,4,NNc1ccc(F)cc1.O=C(O)CCCC(=O)c1ccccc1>>O=C(O)CCc1c(-c2ccccc2)[nH]c2ccc(F)cc12 -US20070203131A1,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(Br)cc1C(=O)c1ccccc1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Br)cc2C(=O)c2ccccc2)cc1 -US06451805B1,7,O=Cc1ccc(-c2nn(Cc3ccccc3)c3ncncc23)o1>>OCc1ccc(-c2nn(Cc3ccccc3)c3ncncc23)o1 -US08258133B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@@]1(N)[C@H]2[C@@H](C[C@@H]1O)[C@]2(F)C(=O)OCC>>CCOC(=O)[C@@]1(NC(=O)OC(C)(C)C)[C@H]2[C@@H](C[C@@H]1O)[C@]2(F)C(=O)OCC -US05942537,6,O=C(O)[C@@H]1C[C@@H](C(=O)O)N(C(=O)OCc2ccccc2)C1>>O=C(O)[C@H]1CN[C@H](C(=O)O)C1 -US05750531,1,CCc1nc(Cl)nc(Cl)c1C.c1ccc2c(c1)CCNC2>>CCc1nc(Cl)nc(N2CCc3ccccc3C2)c1C -US20100305145A1,6,CCOC(=O)CCNS(=O)(=O)c1ccccc1>>O=C(O)CCNS(=O)(=O)c1ccccc1 -US20100216766A1,7,O=[N+]([O-])c1ccc(Oc2ncnc3cc(-c4ccccc4)[nH]c23)c(F)c1>>Nc1ccc(Oc2ncnc3cc(-c4ccccc4)[nH]c23)c(F)c1 -US20150236274A1,1,Oc1ccc(-c2ccc(Br)cc2)cc1.c1ccc2c(c1)[nH]c1ccccc12>>Oc1ccc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1 -US08609696B2,4,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.Nc1ccc(F)cc1N>>CC(C)(C)OC(=O)N1CCC(c2nc3cc(F)ccc3[nH]2)CC1 -US04525478,6,CCOC(=O)C1=C(C)NC(C(OCC)OCC)=C(C(=O)OCC)C1c1cccs1>>CCOC(=O)C1=C(C)NC(C=O)=C(C(=O)OCC)C1c1cccs1 -US07332623B2,3,C#C[Si](C)(C)C.Ic1ccccc1I>>C[Si](C)(C)C#Cc1ccccc1I -US08481731B2,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Clc1cc(Cl)ncn1>>CC(C)(C)OC(=O)N1CCC(Oc2cc(Cl)ncn2)CC1 -US05200111,1,C[C@@H](O)C[C@@H](C)O.N#Cc1ccc(-c2ccc(O)cc2)cc1>>C[C@H](O)C[C@@H](C)Oc1ccc(-c2ccc(C#N)cc2)cc1 -US20140155384A1,3,Cc1ccc(B2OC(C)(C)C(C)(C)O2)s1.Cc1ccc2c(c1)c1c(n2-c2cccc(Br)c2)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2-c2cccc(-c3ccc(C)s3)c2)CCN(C)C1 -US08410117B2,2,CC(=O)Oc1cccc(-c2cn3ccc(N)nc3n2)c1.CN(C)C(=O)c1cnn(C)c1C(=O)O>>CC(=O)Oc1cccc(-c2cn3ccc(NC(=O)c4c(C(=O)N(C)C)cnn4C)nc3n2)c1 -US20090247517A1,9,O=c1c2nc(Br)n(-c3ccccc3)c2nc(-c2ccc(C(F)(F)F)cc2)n1-c1ccc(Cl)cc1.[C-]#N>>N#Cc1nc2c(=O)n(-c3ccc(Cl)cc3)c(-c3ccc(C(F)(F)F)cc3)nc2n1-c1ccccc1 -US20120129840A1,1,CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1.CCN1CCCNCC1>>CCCC(C(=O)OC)c1c(C)nc(N2CCCN(CC)CC2)nc1-c1ccc(C)cc1 -US20110034526A1,1,CCS(=O)(=O)c1cc(F)cc(F)c1.Cc1cc(O)ccc1-n1cnc2c(C(F)(F)F)cccc21>>CCS(=O)(=O)c1cc(F)cc(Oc2ccc(-n3cnc4c(C(F)(F)F)cccc43)c(C)c2)c1 -US20120088772A1,7,N#Cc1ncccn1>>NCc1ncccn1 -US20070117798A1,1,CC(=O)CCl.C[C@H](N)c1ccc(F)cc1>>CC(=O)CN[C@@H](C)c1ccc(F)cc1 -US07759366B2,1,CS(=O)c1ccc(N2C(=O)N(Cc3ccccc3Br)C(C)(C)C2=O)cc1C(F)(F)F.Nc1ccc(F)cc1F>>CS(=O)c1ccc(N2C(=O)N(Cc3ccccc3Nc3ccc(F)cc3F)C(C)(C)C2=O)cc1C(F)(F)F -US20150250169A1,1,BrCc1ccccc1.CCCNC1=C(O)C(=O)O[C@@H]1[C@@H]1COC(C)(C)O1>>CCCNC1=C(OCc2ccccc2)C(=O)O[C@@H]1[C@@H]1COC(C)(C)O1 -US08791102B2,2,O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2c(F)cc(F)cc2F)CN1.O=C(O)Cn1nccn1>>O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2c(F)cc(F)cc2F)CN1C(=O)Cn1nccn1 -US20120264735A1,6,CCOc1cnc(-c2cccc(Cc3nn(-c4cnn(CCOCc5ccccc5)c4)ccc3=O)c2)nc1>>CCOc1cnc(-c2cccc(Cc3nn(-c4cnn(CCO)c4)ccc3=O)c2)nc1 -US05288735,6,CN1NC(S(N)(=O)=O)=[SH]C1=NC(=O)CNC(=O)OCc1ccccc1>>CN1NC(S(N)(=O)=O)=[SH]C1=NC(=O)CN -US06326359B1,1,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COS(C)(=O)=O)nc32)[C@H](O)[C@@H]1O.CS(=O)(=O)N[C@@H]1CC[C@@H](N)CC1>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN[C@@H]4CC[C@@H](NS(C)(=O)=O)CC4)nc32)[C@H](O)[C@@H]1O -US20070149502A1,6,O=C(NC(Cc1ccc2[nH]ncc2c1)C(=O)N1CCN(C(=O)OCc2ccccc2)CC1)N1CCC(N2Cc3ccccc3NC2=O)CC1>>O=C(NC(Cc1ccc2[nH]ncc2c1)C(=O)N1CCNCC1)N1CCC(N2Cc3ccccc3NC2=O)CC1 -US08592452B2,1,CCc1c(F)ccc(C#N)c1Cl.C[C@@H]1NCC[C@@H]1O>>CCc1c(N2CC[C@H](O)[C@@H]2C)ccc(C#N)c1Cl -US07560558B2,1,COc1cc2nccc(Cl)c2cc1OC.Oc1cc2ccccc2nc1-c1ccc(F)cc1>>COc1cc2nccc(Oc3cc4ccccc4nc3-c3ccc(F)cc3)c2cc1OC -US20110086853A1,2,CC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1.CNCCC(C)C>>CC(C)CCN(C)S(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CCOCC1 -US20150175571A1,1,BrCC1CC1.COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)NCC[C@]314>>COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314 -US08183262B2,1,Cc1cc(-c2ccc(Cl)c(Cl)c2)nc(Cl)n1.Ic1c[nH]cn1>>Cc1cc(-c2ccc(Cl)c(Cl)c2)nc(-n2cnc(I)c2)n1 -US05017703,6,O=C1c2ccccc2C(=O)N1CCN1CCC(c2c[nH]c3ccccc23)CC1>>NCCN1CCC(c2c[nH]c3ccccc23)CC1 -US20080085905A1,2,CCC(N)(CC)C(=O)OC.CCN(CC)c1ncc(C(=O)O)nc1OC(C)C>>CCN(CC)c1ncc(C(=O)NC(CC)(CC)C(=O)OC)nc1OC(C)C -US20080318963A1,2,CCOC(=O)Nc1nc2ccc(F)cc2nc1OC.Clc1ccccc1N1CCNCC1>>COc1nc2cc(F)ccc2nc1NC(=O)N1CCN(c2ccccc2Cl)CC1 -US20100210694A1,1,CC(=O)Oc1ccccc1C(=O)OCCl.O=C(O)c1ccc(OCC(CO[N+](=O)[O-])O[N+](=O)[O-])cc1>>CC(=O)Oc1ccccc1C(=O)OCOC(=O)c1ccc(OCC(CO[N+](=O)[O-])O[N+](=O)[O-])cc1 -US07999006B2,2,CC(C)(C)OC(=O)NC1CNC1.O=C(O)c1c(F)cc(F)cc1Nc1ccc(I)cc1F>>CC(C)(C)OC(=O)NC1CN(C(=O)c2c(F)cc(F)cc2Nc2ccc(I)cc2F)C1 -US20060148858A1,6,CCc1cccc(CC(=O)OC)c1OCCCc1cn(-c2ccc(Cl)cn2)nc1C(C)C>>CCc1cccc(CC(=O)O)c1OCCCc1cn(-c2ccc(Cl)cn2)nc1C(C)C -US20150150845A1,2,CC1(C)c2cc(C(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21.CS(=O)(=O)CCN>>CC1(C)c2cc(C(=O)NCCS(C)(=O)=O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 -US08486967B2,1,Cc1cc(Cl)ncn1.c1ccc(C2CCCc3sc(NC4CCNCC4)nc32)cc1>>Cc1cc(N2CCC(Nc3nc4c(s3)CCCC4c3ccccc3)CC2)ncn1 -US20140323530A1,7,CC(C)C(O)C#Cc1cccc(OCCN)c1>>CC(C)C(O)CCc1cccc(OCCN)c1 -US20080312234A1,2,CCCCNc1nc(C(F)(F)F)ccc1C=CC(=O)O.Cc1cc(CN)cc(F)c1NS(C)(=O)=O>>CCCCNc1nc(C(F)(F)F)ccc1C=CC(=O)NCc1cc(C)c(NS(C)(=O)=O)c(F)c1 -US08513239B2,6,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)OC)CC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)O)CC1 -US04230878,2,CCCCCCCCCCC=CCCCNc1ccc(C(=O)O)cc1.NS(=O)(=O)c1ccccc1>>CCCCCCCCCCC=CCCCNc1ccc(C(=O)NS(=O)(=O)c2ccccc2)cc1 -US04256483,1,C[O-].O=c1c2ccccc2nc2ccc(Cl)nn12>>COc1ccc2nc3ccccc3c(=O)n2n1 -US04629495,1,N#Cc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1NC(=O)CCCl>>N#Cc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N1CCC1=O -US20120101083A1,6,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCNC(=O)OC(C)(C)C)CC4)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCN)CC4)no2)cc1C#N -US20150150999A1,6,CC(=O)Oc1ccc(C(=O)OCC2(C)COC(c3ccccc3)OC2)cc1>>CC1(COC(=O)c2ccc(O)cc2)COC(c2ccccc2)OC1 -US07241792B2,9,CC1(C)C2Cc3c(n[nH]c3C(N)=O)C21>>CC1(C)C2Cc3c(n[nH]c3C#N)C21 -US05814646,7,O=[N+]([O-])c1ccc(Oc2ccc3ccccc3n2)cc1>>Nc1ccc(Oc2ccc3ccccc3n2)cc1 -US08642585B2,1,C[C@@H](CO)CBr.Cc1cc(O)cc(C)c1Br>>Cc1cc(OC[C@@H](C)CO)cc(C)c1Br -US20080132540A1,2,CC(=O)Cl.O=C(/C=C/c1ccccc1)N(c1ccc2cc[nH]c2c1)C1CCN(Cc2ccccc2)CC1>>CC(=O)n1ccc2ccc(N(C(=O)/C=C/c3ccccc3)C3CCN(Cc4ccccc4)CC3)cc21 -US20040034041A1,1,ClCc1ccccn1.O=c1[nH]c2ccccc2c(=O)o1>>O=c1oc(=O)n(Cc2ccccn2)c2ccccc12 -US08754068B2,3,C=C(C)[C@@H]1CC[C@]2(COC(=O)c3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CCCC[Sn](CCCC)(CCCC)c1cc(C(=O)OCC)[nH]n1>>C=C(C)[C@@H]1CC[C@]2(COC(=O)c3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6cc(C(=O)OCC)[nH]n6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20100144823A1,4,C#CC(C)(O)CSCC.CS(=O)(=O)Nc1cc(C(F)(F)F)c(F)cc1I>>CCSCC(C)(O)c1cc2cc(F)c(C(F)(F)F)cc2n1S(C)(=O)=O -US20010006969A1,1,C=CCN.CNc1nc(Cl)nc2c(C(C)C)csc12>>C=CCNc1nc(NC)c2scc(C(C)C)c2n1 -US08188098B2,2,CC(C)COC(=O)Cl.CS(=O)(=O)c1ccc(Oc2ncnc3c2cnn3C2CCNCC2)cc1>>CC(C)COC(=O)N1CCC(n2ncc3c(Oc4ccc(S(C)(=O)=O)cc4)ncnc32)CC1 -US20150111866A1,6,COC(=O)c1ccc(-c2cnc(OC)c(-c3cnc(N4CC(F)C4)nc3CN3C(=O)O[C@H](c4cccc(OC(F)(F)F)c4)[C@@H]3C)c2)c(C)c1>>COc1ncc(-c2ccc(C(=O)O)cc2C)cc1-c1cnc(N2CC(F)C2)nc1CN1C(=O)O[C@H](c2cccc(OC(F)(F)F)c2)[C@@H]1C -US20100016399A1,2,COc1ccc(C2CC3(CCCCC3)N(CC(=O)Cl)C2=O)cc1.Nc1cc(F)cc(F)c1>>COc1ccc(C2CC3(CCCCC3)N(CC(=O)Nc3cc(F)cc(F)c3)C2=O)cc1 -US20120010186A1,1,CC(C)(C)OC(=O)Cn1nnc(-c2cnc(Br)s2)n1.Cc1ccc(Cl)cc1N1CC2CNCC2C1>>Cc1ccc(Cl)cc1N1CC2CN(c3ncc(-c4nnn(CC(=O)OC(C)(C)C)n4)s3)CC2C1 -US20110212918A1,2,COc1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1.Nc1ccc2c(c1)B(O)OC2>>COc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c([N+](=O)[O-])c1 -US20130237535A1,3,Brc1ccc2nccn2n1.CC1(C)OB(c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)OC1(C)C>>O=C1COC2(CCN(S(=O)(=O)c3ccc(-c4ccc5nccn5n4)cc3)CC2)CN1C1CC1 -US20140066420A1,6,CCOC(=O)CCC(=O)N1CC(Oc2ccccc2C(C)(C)C)C1>>CC(C)(C)c1ccccc1OC1CN(C(=O)CCC(=O)O)C1 -US20090221555A1,1,CNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.Nc1ccc2c(c1)NCCNC2=O>>CNC(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2)NCCNC3=O)ncc1Cl -US20130040930A1,2,CCOC(=O)Cl.COC(=O)c1ccc(C(C)(C)N)cc1>>CCOC(=O)NC(C)(C)c1ccc(C(=O)OC)cc1 -US20080312281A1,1,CC(C)(C)OC(=O)N1CCC(CCCO)CC1.Clc1ccncc1>>CC(C)(C)OC(=O)N1CCC(CCCOc2ccncc2)CC1 -US05646308,7,CNC(=S)C1=C(O)C(COC)(COC)Oc2ccc([N+](=O)[O-])cc21>>CNC(=S)C1c2cc([N+](=O)[O-])ccc2OC(COC)(COC)C1O -US07943609B2,6,CC(C)[C@H]1COCc2nc3c(N)nc4cc(OCc5ccccc5)ccc4c3n21>>CC(C)[C@H]1COCc2nc3c(N)nc4cc(O)ccc4c3n21 -US20050038035A1,2,CC(C)(C)OC(=O)Nc1cccc(CCO)n1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCc2cccc(NC(=O)OC(C)(C)C)n2)cc1 -US05523407,2,CC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1O.Cc1cc(C)c2ncc(N)c(-c3ccccc3Cl)c2c1>>Cc1cc(C)c2ncc(NC(=O)c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)c(-c3ccccc3Cl)c2c1 -US20100298343A1,1,CCOC(=O)C(Cc1ccc(Br)cc1)c1[nH]c2ccc(OC)cc2c1SC(C)(C)C.CI>>CCOC(=O)C(Cc1ccc(Br)cc1)c1c(SC(C)(C)C)c2cc(OC)ccc2n1C -US06486156B1,10,COC(=O)c1sc(C)cc1-c1ccc(F)cc1.O=C1CCC(=O)N1Br>>COC(=O)c1sc(CBr)cc1-c1ccc(F)cc1 -US20150119385A1,9,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.N>>CC(C)S(=O)(=O)c1ccccc1Nc1nc(N)ncc1Cl -US03951999,9,CCc1ccc(C(=O)c2ccc(Cl)cc2)c(O)c1.NO>>CCc1ccc(C(=NO)c2ccc(Cl)cc2)c(O)c1 -US05506191,6,CCOC(=O)c1cccnc1C#C[Si](C)(C)C>>C#Cc1ncccc1C(=O)OCC -US20150166486A1,1,CC(N)(CO)CO.Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(Cl)nc2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(NC(C)(CO)CO)nc2)c1 -US20120190679A1,6,CC(C)(C)OC(=O)NC1(C(=O)NC(Cc2nccs2)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1>>NC1(C(=O)NC(Cc2nccs2)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 -US04973588,1,CN(C)C(=O)Sc1nc(-c2ccccc2)c[nH]1.O=[N+]([O-])c1ccc(Cl)nc1>>CN(C)C(=O)Sc1nc(-c2ccccc2)cn1-c1ccc([N+](=O)[O-])cn1 -US20090221555A1,1,Clc1ncc(Cl)c(Cl)n1.NC(=O)c1cccc(F)c1N>>NC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl -US20150197509A1,2,COC(=O)CNC(C)(C)C.O=S(=O)(Cl)c1ccc(F)cc1>>COC(=O)CN(C(C)(C)C)S(=O)(=O)c1ccc(F)cc1 -US20100063285A1,3,C=Cc1ccc(C#N)cc1.CCOC(C)n1cc(I)cn1>>CCOC(C)n1cc(/C=C/c2ccc(C#N)cc2)cn1 -US20120165310A1,6,CCC(CC)OCCOCc1ccccc1>>CCC(CC)OCCO -US07851615B2,2,CCCCCCCCCCCC(=O)O.COc1ccc(C(OC(c2ccccc2)C2CC(O)CN2C(=O)CCCCCN)c2ccc(OC)cc2)cc1>>CCCCCCCCCCCC(=O)NCCCCCC(=O)N1CC(O)CC1C(OC(c1ccc(OC)cc1)c1ccc(OC)cc1)c1ccccc1 -US07928119B2,2,Cc1cc(C(=O)O)nn1C.Cc1ccc(S(=O)(=O)NC(=O)OCCc2ccc(Nc3cc(Cl)c(C(F)(F)F)cc3N)cc2)cc1>>Cc1ccc(S(=O)(=O)NC(=O)OCCc2ccc(Nc3cc(Cl)c(C(F)(F)F)cc3NC(=O)c3cc(C)n(C)n3)cc2)cc1 -US07615648B2,1,CC(C)CNC[C@@H]1CCCN1C(=O)OC(C)(C)C.O=Cc1cc(Cl)cc(Cl)c1>>CC(C)CN(Cc1cc(Cl)cc(Cl)c1)C[C@@H]1CCCN1C(=O)OC(C)(C)C -US04788305,7,CC1(C)[C@@H]2C(=O)O[C@@H](C(Cl)(Cl)Cl)[C@@H]21>>CC1(C)[C@H]2[C@@H]1[C@H](C(Cl)(Cl)Cl)O[C@@H]2O -US06232430B1,2,C=C(C)C(=O)Cl.C[SiH](C)OC(O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1>>C=C(C)C(=O)OC(O[SiH](C)C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1 -US08227615B2,3,Cc1ccccc1C[Zn+].O=C(Nc1cccc(Br)n1)C1(c2ccc3c(c2)OCO3)CC1>>Cc1ccccc1Cc1cccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)n1 -US04500343,2,CC(C)(C)c1cc(N)sn1.CC(CCCl)C(=O)O>>CC(CCCl)C(=O)Nc1cc(C(C)(C)C)ns1 -US07034015B2,1,CN1CC(=O)NC1=O.Cc1ccccc1C(=O)c1ccc(Nc2ccc(Br)cc2COCCO)cc1Cl>>Cc1ccccc1C(=O)c1ccc(Nc2ccc(Br)cc2COCCN2C(=O)CN(C)C2=O)cc1Cl -US20080255144A1,7,CC(=O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3-c3ccc(F)cc3)CC2)c(F)c1>>CC(O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3-c3ccc(F)cc3)CC2)c(F)c1 -US04413141,2,COC(=O)C(N)(CCCN)C(F)F>>NC1(C(F)F)CCCNC1=O -US20050234101A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.C=Cc1cc(I)ccc1OCCO>>C=Cc1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCO -US20120108577A1,1,N#Cc1ccc2c(c1)N(CCN1CCC(N)CC1)C(=O)CO2.O=C/C=C/c1cc(F)ccc1F>>N#Cc1ccc2c(c1)N(CCN1CCC(NC/C=C/c3cc(F)ccc3F)CC1)C(=O)CO2 -US07105533B2,8,CCC(O)c1ccc(-c2ccccn2)c(OC)c1>>CCC(=O)c1ccc(-c2ccccn2)c(OC)c1 -US20150218092A1,7,COc1cc([N+](=O)[O-])ccc1OCCOC1CCCCO1>>COc1cc(N)ccc1OCCOC1CCCCO1 -US08263587B2,7,O=C1NC(=O)C(=Cc2ccc3c(c2)CN(c2ccccn2)CCO3)S1>>O=C1NC(=O)C(Cc2ccc3c(c2)CN(c2ccccn2)CCO3)S1 -US06576626B2,9,CCOC(C)(OCC)P(=O)(C[C@H](O)CCl)OCC.N>>CCOC(C)(OCC)P(=O)(C[C@H](O)CN)OCC -US06107320,1,C=O.Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(CC(C)C)cc2N)c1C>>CNc1cc(CC(C)C)ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C -US20050227980A1,2,CCO.Cc1ccc(F)c(C(=O)O)c1>>CCOC(=O)c1cc(C)ccc1F -US20120149721A1,2,CCC(=O)Cl.COc1cc(OCC2CC2)c(-c2ncnc3c(C(=O)NC4CCNCC4)c(C)[nH]c23)cc1F>>CCC(=O)N1CCC(NC(=O)c2c(C)[nH]c3c(-c4cc(F)c(OC)cc4OCC4CC4)ncnc23)CC1 -US04520197,7,CCOP(C)(=O)c1ccccc1[N+](=O)[O-]>>CCOP(C)(=O)c1ccccc1N -US20080153838A1,3,C#Cc1cccc(NC(=O)Nc2cc(C(C)(C)C)on2)c1.Ic1cn[nH]c1>>CC(C)(C)c1cc(NC(=O)Nc2cccc(C#Cc3cn[nH]c3)c2)no1 -US20090215841A1,1,CCN(C(=O)OCc1ccccc1)[C@H]1Cc2ccc(Br)cc2C1.N=C(c1ccccc1)c1ccccc1>>CCN(C(=O)OCc1ccccc1)[C@H]1Cc2ccc(N=C(c3ccccc3)c3ccccc3)cc2C1 -US20030148470A1,6,Nc1nc(=O)n([C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)cc1C#CCOCCOCCNC(=O)C(F)(F)F>>NCCOCCOCC#Cc1cn([C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)nc1N -US20100144786A1,6,CCc1nc2c(F)ccc(O[C@@H](C)C(=O)OC)c2c(OC(F)F)c1Cc1ccc(Cl)cc1>>CCc1nc2c(F)ccc(O[C@@H](C)C(=O)O)c2c(OC(F)F)c1Cc1ccc(Cl)cc1 -US20150191439A1,1,COc1ccc2cc(C=O)sc2c1.NC12CC3CC(CC(C3)C1)C2>>COc1ccc2cc(CNC34CC5CC(CC(C5)C3)C4)sc2c1 -US05145865,6,COC(=O)c1ccc(OCC2CC(=O)N(c3ccc(OS(C)(=O)=O)cc3)C2)cc1>>CS(=O)(=O)Oc1ccc(N2CC(COc3ccc(C(=O)O)cc3)CC2=O)cc1 -US20110184188A1,1,Cc1cc(CCl)ccc1[N+](=O)[O-].O=C1NC(=O)c2ccccc21>>Cc1cc(CN2C(=O)c3ccccc3C2=O)ccc1[N+](=O)[O-] -US20070265278A1,4,NNc1ccccc1.O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)NC2CCCCC2)c1>>O=C(O)Cc1c(-c2ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c2)[nH]c2ccccc12 -US20050234029A1,1,Brc1ccc(-c2cc(-c3c(-c4ccccn4)nc4ccccn34)ccn2)cc1.CN1CCNCC1>>CN1CCN(c2ccc(-c3cc(-c4c(-c5ccccn5)nc5ccccn45)ccn3)cc2)CC1 -US08399674B2,3,C=Cc1ccncc1.COc1ccccc1CNc1ccc2cc(Br)ccc2n1>>COc1ccccc1CNc1ccc2cc(/C=C/c3ccncc3)ccc2n1 -US05405861,1,ClCCBr.Cn1ccnc1S>>Cn1ccnc1SCCCl -US08445674B2,2,C[C@@H]1NCCN(CCC(C)(C)C(=O)N2CCC3(CC3)[C@H](O)C2)C1=O.O=C=Nc1ccc(C(F)(F)F)c(Cl)c1>>C[C@H]1C(=O)N(CCC(C)(C)C(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)Nc1ccc(C(F)(F)F)c(Cl)c1 -US20080200468A1,6,COC(=O)c1ccsc1NC(=O)CCc1ccc(-c2ccccc2)cc1>>O=C(CCc1ccc(-c2ccccc2)cc1)Nc1sccc1C(=O)O -US04420487,4,Nc1cc(Cl)c(S(N)(=O)=O)cc1N.O=C(O)C(Cl)Cl>>NS(=O)(=O)c1cc2[nH]c(C(Cl)Cl)nc2cc1Cl -US20030139449A1,2,CN[C@H](CC1CCCCC1)CN1CCN(c2ccccc2OC)CC1.O=C(O)C1CCCCC1>>COc1ccccc1N1CCN(C[C@@H](CC2CCCCC2)N(C)C(=O)C2CCCCC2)CC1 -US07342012B2,6,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCN1C(=O)OCc1ccccc1>>CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCN1 -US20040122016A1,5,CC(=O)c1cc(N)cs1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)c1cc(NC(=O)OC(C)(C)C)cs1 -US20050197342A1,3,Brc1ccc2nccnc2c1.Cc1c(Cl)ncnc1Cl>>Cc1c(Cl)ncnc1-c1ccc2nccnc2c1 -US20030225268A1,1,C1NCC2CNCC1C2.Clc1ccc(I)cn1>>Clc1ccc(N2CC3CNCC(C3)C2)cn1 -US20110009421A1,2,CCO.O=C(O)c1cc(F)cc(Br)c1>>CCOC(=O)c1cc(F)cc(Br)c1 -US08455658B2,7,C=C(C)c1nc(NC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1>>CC(C)c1nc(NC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1 -US06133266,2,CC1(C)OCc2cc([C@@H](O)C(=O)O)ccc2O1.N[C@H]1CCc2ccc(O)cc2C1>>CC1(C)OCc2cc([C@@H](O)C(=O)N[C@H]3CCc4ccc(O)cc4C3)ccc2O1 -US20140357858A1,2,CC(C)c1ccccc1C(=O)Cl.Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1>>CC(C)c1ccccc1C(=O)Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1 -US05656198,1,CCCC[C@@H]1CC[C@@H](C(=O)O)CC1.Oc1ccc(Br)cc1>>CCCC[C@@H]1CC[C@@H](C(=O)Oc2ccc(Br)cc2)CC1 -US20140011800A1,6,CC[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1Nc1c(C(N)=O)cnn2cc(-c3ccc(CNC(=O)COC)nc3)cc12>>CC[C@H]1CNC[C@H]1Nc1c(C(N)=O)cnn2cc(-c3ccc(CNC(=O)COC)nc3)cc12 -US04977146,1,CCCBr.COc1cc(C(=O)CCC(=O)c2cc(OCc3ccccc3)c(O)c(S(=O)(=O)CCO)c2)cc(OC)c1OC>>CCCOc1c(OCc2ccccc2)cc(C(=O)CCC(=O)c2cc(OC)c(OC)c(OC)c2)cc1S(=O)(=O)CCO -US07229999B2,2,COCCOc1ncc(C(=O)O)cc1Br.N[C@@H]1CCCC[C@H]1O>>COCCOc1ncc(C(=O)N[C@@H]2CCCC[C@H]2O)cc1Br -US06967198B2,6,CC(C)(C)OC(=O)N[C@@H](CCc1ccccc1)C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>N[C@@H](CCc1ccccc1)C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O -US20100210647A1,1,C1COCCN1.Cc1cc(NCC2CCOCC2)c2[nH]c(C3=N[C@H](CCO)CS3)cc2c1>>Cc1cc(NCC2CCOCC2)c2[nH]c(C3=N[C@@H](CCN4CCOCC4)CS3)cc2c1 -US20120202992A1,6,CCOC(=O)c1c(S(=O)(=O)NC)nn2c(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)cnc12>>CNS(=O)(=O)c1nn2c(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)cnc2c1C(=O)O -US04046905,10,CCc1ccc(-c2nc3ccccc3o2)c(F)c1.O=C1CCC(=O)N1Br>>CC(Br)c1ccc(-c2nc3ccccc3o2)c(F)c1 -US07220863B2,9,Fc1cnc(F)c(F)c1.NN>>NNc1ncc(F)cc1F -US20060287309A1,4,CC(C)(C)OC(=O)N(CCCl)CCCl.Nc1cccc2c1OC(F)(F)C(F)(F)O2>>CC(C)(C)OC(=O)N1CCN(c2cccc3c2OC(F)(F)C(F)(F)O3)CC1 -US20140309223A1,7,COc1cc([N+](=O)[O-])ccc1Oc1ccc(Cl)c(Cl)c1>>COc1cc(N)ccc1Oc1ccc(Cl)c(Cl)c1 -US07576100B2,1,CCCC=C1CCNCC1.C[C@H](CI)CN1C(=O)CSc2ccccc21>>CCCC=C1CCN(C[C@@H](C)CN2C(=O)CSc3ccccc32)CC1 -US04211776,2,CC(=O)OC(C)=O.COc1ccc(Cl)cc1N>>COc1ccc(Cl)cc1NC(C)=O -US20100249124A1,3,CC(c1ccc(Br)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.N#CCc1cccc(B(O)O)c1>>CC(c1ccc(-c2cccc(CC#N)c2)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F -US07459452B2,6,CN1CCN(C(=O)OC(C)(C)C)CC1(C)c1nc(O)c(O)c(C(=O)NCc2ccc(F)cc2)n1>>CN1CCNCC1(C)c1nc(O)c(O)c(C(=O)NCc2ccc(F)cc2)n1 -US20040014968A1,2,Nc1ccccn1.O=C(O)C(CC1CCCC1)c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(Nc1ccccn1)C(CC1CCCC1)c1ccc(Cl)c([N+](=O)[O-])c1 -US09139576B2,1,CS(=O)(=O)OCc1ccc(-c2ccc3c(nnn3CC3CC3)c2C(F)(F)F)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc(-c2ccc3c(nnn3CC3CC3)c2C(F)(F)F)cc1 -US20130231329A1,4,Nc1ccccc1N.O=C(O)C(O)c1cccc(Br)c1>>OC(c1cccc(Br)c1)c1nc2ccccc2[nH]1 -US20100216802A1,1,CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C1CCCC1.Nc1ccc(O)cc1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(O)cc3)nc2N1C1CCCC1 -US20090099161A1,1,CC(C)(O)CN.O=[N+]([O-])c1cnc2ccc(Br)cc2c1O>>CC(C)(O)CNc1c([N+](=O)[O-])cnc2ccc(Br)cc12 -US20040236084A1,1,CI.Clc1ncc(Br)c(NC2CCCC2)n1>>CN(c1nc(Cl)ncc1Br)C1CCCC1 -US08299086B2,1,CCc1cc(-c2ncc(-c3cc(C)nc(NC(C)C)n3)o2)cc(C)c1O.OC[C@H](O)CCl>>CCc1cc(-c2ncc(-c3cc(C)nc(NC(C)C)n3)o2)cc(C)c1OCC(O)CO -US20110046134A1,2,O=C(NCC(=O)N1CCNCC1)c1ccc(-c2ccccc2)cc1.O=C(O)c1cc(C(F)(F)F)ccc1F>>O=C(NCC(=O)N1CCN(C(=O)c2cc(C(F)(F)F)ccc2F)CC1)c1ccc(-c2ccccc2)cc1 -US07074816B2,1,CC(C)(C)C(=O)OCCl.Cc1cc(-c2nc(-c3ccc(OCC(C)C)c([N+](=O)[O-])c3)n[nH]2)ccn1>>Cc1cc(-c2nc(-c3ccc(OCC(C)C)c([N+](=O)[O-])c3)nn2COC(=O)C(C)(C)C)ccn1 -US20090186900A1,3,CCc1cccc(Br)c1.COc1ccc(B(O)O)cc1>>CCc1cccc(-c2ccc(OC)cc2)c1 -US06372783B1,2,CO.O=C(O)Cc1cc2ccccc2o1>>COC(=O)Cc1cc2ccccc2o1 -US08101649B2,2,CCOC(=O)CCc1c[nH]c2ccccc12.NN>>NNC(=O)CCc1c[nH]c2ccccc12 -US20030083315A1,1,CCOC(=O)CCCSc1nc2cc(F)c(F)cc2[nH]1.ClCc1cccc2ccccc12>>CCOC(=O)CCCSc1nc2cc(F)c(F)cc2n1Cc1cccc2ccccc12 -US20040006141A1,6,CCOC(=O)C(C)(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)cc1)Oc1ccc(C(C)C)cc1>>CC(C)c1ccc(OC(C)(Cc2ccc(OCCNC(=O)c3ccc(-c4ccccn4)cc3)cc2)C(=O)O)cc1 -US20150225397A1,9,COC(=O)c1ccc(-c2cccc(-c3nc(C)nc4c3CC[C@H]3[C@H](C)C(=O)C(C#N)=C[C@]43c3ccccc3)c2)cc1.[NH4+]>>Cc1nc(-c2cccc(-c3ccc(C(N)=O)cc3)c2)c2c(n1)[C@@]1(c3ccccc3)C=C(C#N)C(=O)[C@@H](C)[C@@H]1CC2 -US20130150342A1,2,CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)O.CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCC(C4)N5)cn3)nc2n1C1CCCC1>>CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)N1C2CCC1CN(C(=O)c1ccc(Nc3ncc4cc(C(=O)N(C)C)n(C5CCCC5)c4n3)nc1)C2 -US20110135668A1,2,Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(F)F)n2)c(OC(C)C)cc1C1CCNCC1.O=C(Cl)[C@@H]1CCCN1>>Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(F)F)n2)c(OC(C)C)cc1C1CCN(C(=O)[C@@H]2CCCN2)CC1 -US04964896,6,CCOC(=O)c1c(C)n(C)c(-c2ccc(Br)cc2)cc1=O>>Cc1c(C(=O)O)c(=O)cc(-c2ccc(Br)cc2)n1C -US20080076774A1,6,CCS(=O)(=O)c1cc(NCCN2CCCC2)c(C)c(N2CCN(C(=O)OC(C)(C)C)CC2)c1>>CCS(=O)(=O)c1cc(NCCN2CCCC2)c(C)c(N2CCNCC2)c1 -US20090234016A1,6,CCOC(=O)Cc1cccc(OCc2c(C)cccc2C)c1>>Cc1cccc(C)c1COc1cccc(CC(=O)O)c1 -US06498161B1,1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCC(CO)CC1>>CC(C)(C)OC(=O)N1CCC(COCc2ccccc2)CC1 -US04363816,1,CN1CCNCC1.Cc1c2c(n(C)c1C)C(=O)Nc1ccccc1N2C(=O)CCl>>Cc1c2c(n(C)c1C)C(=O)Nc1ccccc1N2C(=O)CN1CCN(C)CC1 -US08022062B2,6,COc1ccc(CNC(=O)C(F)(F)F)cc1>>O=C(NCc1ccc(O)cc1)C(F)(F)F -US04829067,7,O=C(OCCN1CCCCC1)c1cc([N+](=O)[O-])cc2cc(-c3ccccc3)oc12>>Nc1cc(C(=O)OCCN2CCCCC2)c2oc(-c3ccccc3)cc2c1 -US04617302,3,CCC(=O)Cl.O=C1Nc2ccccc2C12CC2>>CCC(=O)c1ccc2c(c1)C1(CC1)C(=O)N2 -US05883262,1,CCOC(=O)CCl.Oc1ccc(Cn2cccn2)cc1>>CCOC(=O)COc1ccc(Cn2cccn2)cc1 -US20150141406A1,1,BrC1CCCC1.O=Cc1ccc[nH]1>>O=Cc1cccn1C1CCCC1 -US20070129416A1,2,CCOc1cc(Cl)c(S(C)(=O)=O)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1.O=C(Cl)Cl>>CCOc1cc(Cl)c(S(C)(=O)=O)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl -US20090286791A1,6,COC(=O)c1ccc(-c2nnc(C(C)C)o2)nc1>>CC(C)c1nnc(-c2ccc(C(=O)O)cn2)o1 -US05663337,4,N#Cc1ccc(N(C(=O)C(F)(F)F)c2cccc3c2CCC=C3)cc1.O=C(OO)c1cccc(Cl)c1>>N#Cc1ccc(N(C(=O)C(F)(F)F)c2cccc3c2CCC2OC32)cc1 -US20110190276A1,6,CC(C)(C)[Si](C)(C)OC[C@@H]1CN2CCOC[C@@H]2CN1Cc1ccccc1>>OC[C@@H]1CN2CCOC[C@@H]2CN1Cc1ccccc1 -US08048893B2,1,Brc1ccc(-c2c[nH]nc2OCc2ccccc2)cc1.ClCCN1CCCCC1>>Brc1ccc(-c2cn(CCN3CCCCC3)nc2OCc2ccccc2)cc1 -US20110044938A1,7,CCNC(=O)OC[C@H]1CCc2c(sc(NC(=O)/C=C/c3cccnc3)c2C#N)C1>>CCNC(=O)OC[C@H]1CCc2c(sc(NC(=O)CCc3cccnc3)c2C#N)C1 -US04348399,7,CCCCCCCCCCCCCCCCNc1ccc(CC(=O)OCC)cc1>>CCCCCCCCCCCCCCCCNc1ccc(CCO)cc1 -US20150246922A1,3,O=C1NCCn2c1cc1c(F)c(F)cc(Br)c12.OB(O)c1ccc(F)c(F)c1>>O=C1NCCn2c1cc1c(F)c(F)cc(-c3ccc(F)c(F)c3)c12 -US20020094989A1,1,CCC(CC)(CN1C[C@H](C=O)[C@@H](c2cccc(F)c2)C1)C(=O)OCc1ccccc1.CCn1nc(Cc2ccccc2)cc1C1CCNCC1>>CCn1nc(Cc2ccccc2)cc1C1CCN(C[C@H]2CN(CC(CC)(CC)C(=O)OCc3ccccc3)C[C@@H]2c2cccc(F)c2)CC1 -US20140243322A1,2,CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OCCN)ccc2-n2c(C)nnc21.COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)O)c1nnc(C)n1-2>>CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OCCNC(=O)C[C@@H]3N=C(c4ccc(Cl)cc4)c4cc(OC)ccc4-n4c(C)nnc43)ccc2-n2c(C)nnc21 -US20070244130A1,2,COc1ccc(C(=O)C(O)c2ccc(OC)cc2)cc1.O=C(O)CBr>>COc1ccc(C(=O)C(OC(=O)CBr)c2ccc(OC)cc2)cc1 -US07560573B2,1,CN(C)CCC(O)c1cccs1.Fc1cccc2ccccc12>>CN(C)CCC(Oc1cccc2ccccc12)c1cccs1 -US20150094296A1,1,N#C[C@@]1(C2CC2)CCN(c2ccnc(Cl)n2)C1=O.Nc1cnn(C2(CO)CCC2)c1>>N#C[C@@]1(C2CC2)CCN(c2ccnc(Nc3cnn(C4(CO)CCC4)c3)n2)C1=O -US20050171083A1,3,CN(C)C=O.COc1cc(Cl)cc(Cl)c1>>COc1cc(Cl)cc(C=O)c1 -US04260633,2,CC(C)[C@@H](Nc1ccc(C(F)(F)F)cc1Cl)C(=O)O.N#C[C@@H](O)c1cccc(Oc2ccccc2)c1>>CC(C)[C@@H](Nc1ccc(C(F)(F)F)cc1Cl)C(=O)O[C@H](C#N)c1cccc(Oc2ccccc2)c1 -US20100197654A1,1,C[C@@]1(C(=O)Nc2ccc(F)nc2)CCCN1.Clc1nc(Cl)nc(Nc2cc(C3CC3)n[nH]2)n1>>C[C@@]1(C(=O)Nc2ccc(F)nc2)CCCN1c1nc(Cl)nc(Nc2cc(C3CC3)n[nH]2)n1 -US20090023741A1,2,Cc1[nH]c2c(F)ccc(C)c2c1CCN.O=C(Cl)c1ccc(-c2ccccc2)cc1>>Cc1[nH]c2c(F)ccc(C)c2c1CCNC(=O)c1ccc(-c2ccccc2)cc1 -US04929637,1,COCCOCCl.OCCc1ccsc1Br>>COCCOCOCCc1ccsc1Br -US07517875B2,7,COC(=O)c1cccc([N+](=O)[O-])c1N>>COC(=O)c1cccc(N)c1N -US20070299068A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2c(C#N)c[nH]c2c1>>COc1ccc2c(C#N)cn(C(=O)OC(C)(C)C)c2c1 -US06576626B2,7,COC(=O)[C@@H](F)CN(Cc1ccccc1)Cc1ccccc1>>OC[C@@H](F)CN(Cc1ccccc1)Cc1ccccc1 -US20100130474A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1[nH]nc(-c2ccc3ncccc3c2)c1F>>CC(C)(C)OC(=O)n1nc(-c2ccc3ncccc3c2)c(F)c1N -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)CCCCc1ccccc1>>Cc1nc(NC(=O)CCCCc2ccccc2)sc1C(=O)NCc1ccccc1 -US20040053973A1,2,CC(=O)Cl.CC(=O)Nc1cc(-c2sc(C3CCNCC3)nc2-c2cccc(Cl)c2)ccn1>>CC(=O)Nc1cc(-c2sc(C3CCN(C(C)=O)CC3)nc2-c2cccc(Cl)c2)ccn1 -US05610144,6,CC(C(=O)OCc1ccccc1)c1cccc(NC(=O)NCC(=O)N2[C@H](C(=O)OC(C)(C)C)CS[C@@H]2c2cccc(F)c2F)c1>>CC(C(=O)O)c1cccc(NC(=O)NCC(=O)N2[C@H](C(=O)OC(C)(C)C)CS[C@@H]2c2cccc(F)c2F)c1 -US06380238B1,6,COC(=O)c1cc2ccc(Cl)c(F)c2[nH]1>>O=C(O)c1cc2ccc(Cl)c(F)c2[nH]1 -US05686424,2,CC[C@H](C)[C@H](N)C(=O)NC(C)(C)C.O=C(CN1CCC[C@H]1C(=O)O)c1ccc(-c2ccccc2)cc1>>CC[C@H](C)[C@H](N)C(=O)N(C(=O)[C@@H]1CCCN1CC(=O)c1ccc(-c2ccccc2)cc1)C(C)(C)C -US03931209,2,CNN.O=C=Nc1nnc(C(F)(F)F)s1>>CN(N)C(=O)Nc1nnc(C(F)(F)F)s1 -US20020028797A1,1,CC(C)OC(=O)C1CCCN1S(=O)(=O)c1ccc(N2CCC(=O)CC2)cc1.NC[C@H](O)COc1cccc2[nH]c(=O)[nH]c12>>CC(C)OC(=O)C1CCCN1S(=O)(=O)c1ccc(N2CCC(NCC(O)COc3cccc4[nH]c(=O)[nH]c34)CC2)cc1 -US05021581,7,COC(=O)c1ccccc1C(C)Oc1cccc(Cl)c1>>CC(Oc1cccc(Cl)c1)c1ccccc1CO -US20060052627A1,6,CCOC(=O)Cc1ccc(Sc2cccc(N(CCc3ccccc3)CCc3ccccc3)c2)cc1>>O=C(O)Cc1ccc(Sc2cccc(N(CCc3ccccc3)CCc3ccccc3)c2)cc1 -US08426420B2,2,CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)O)n(-c3cccc(F)c3)n2)CC1.O=C(OCc1ccccc1)[C@@H]1CCCN1>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)OCc3ccccc3)n(-c3cccc(F)c3)n2)CC1 -US20120071478A1,1,Clc1cnc2cc(Br)ccc2n1.NCc1cccc(Cl)c1>>Clc1cccc(CNc2cnc3cc(Br)ccc3n2)c1 -US20080176862A1,3,CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2cncc(Br)c2)N=C1N.COc1ccc(F)c(B(O)O)c1>>COc1ccc(F)c(-c2cncc(C3(c4ccc(OS(C)(=O)=O)cc4)N=C(N)N(C)C3=O)c2)c1 -US20110009454A1,2,NCc1ccc(Oc2ccc(F)cc2)cc1.Nc1ccc(C(=O)O)c(N)n1>>Nc1ccc(C(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)c(N)n1 -US20120110702A1,1,Cc1nn(-c2cccnc2)cc1I.NC1CC1>>Cc1nn(-c2cccnc2)cc1NC1CC1 -US07381719B2,6,CCOC(=O)c1ccc(Oc2ccc(CN(CCc3ccccc3)C(=O)OC(C)(C)C)cc2)nc1>>CC(C)(C)OC(=O)N(CCc1ccccc1)Cc1ccc(Oc2ccc(C(=O)O)cn2)cc1 -US07012089B2,7,CN1CCc2cccc3c4c(n(c23)CC1)CCC4>>CN1CCc2cccc3c2N(CC1)C1CCCC31 -US20120302598A1,1,CCOC(=O)N(Cc1ccc(C)nc1)c1cc(Cl)nc(N)c1[N+](=O)[O-].OCC1CCOCC1>>CCOC(=O)N(Cc1ccc(C)nc1)c1cc(OCC2CCOCC2)nc(N)c1[N+](=O)[O-] -US05663169,3,C#CC1(C(F)(F)F)OC(=O)Nc2ccc(Cl)cc21.C1CCNC1.C=O>>O=C1Nc2ccc(Cl)cc2C(C#CCN2CCCC2)(C(F)(F)F)O1 -US08440651B2,1,CC(C)(O)C1CCN(Cc2ccc3nc(Cl)nc(N4CCOCC4)c3n2)CC1.CN(C)c1nc2ccccc2[nH]1>>CN(C)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)ccc2n1 -US20100034827A1,9,Cc1cc(C=O)cc(Oc2nc(Cl)nc(Cl)c2C(C)C)c1.NO>>Cc1cc(C=NO)cc(Oc2nc(Cl)nc(Cl)c2C(C)C)c1 -US05453443,6,COC(=O)CCSC(CCCc1ccccc1)c1ccc(OCCCOc2ccc(C(=O)C(F)(F)F)cc2)cc1>>O=C(O)CCSC(CCCc1ccccc1)c1ccc(OCCCOc2ccc(C(=O)C(F)(F)F)cc2)cc1 -US20100029745A1,1,CC(C)(C)OC(=O)CBr.O=C(CCc1ccc(O)c(F)c1)c1ccc(-c2ccc(C(F)(F)F)cc2)s1>>CC(C)(C)OC(=O)COc1ccc(CCC(=O)c2ccc(-c3ccc(C(F)(F)F)cc3)s2)cc1F -US08327467B2,3,CC(C)(C)OC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1Nc1ccc(F)cc1.NS(=O)(=O)c1ccc(Br)cc1>>CC(C)(C)OC(=O)c1ccc(-c2ccc(S(N)(=O)=O)cc2)cc1Nc1ccc(F)cc1 -US04073911,1,NCCNc1ccccc1.O=C1CCN(Cc2ccccc2)CC1>>c1ccc(CN2CCC(NCCNc3ccccc3)CC2)cc1 -US20090054405A1,1,CC(C)=O.Nc1cc(Br)cnc1Cl>>CC(C)Nc1cc(Br)cnc1Cl -US20060270637A1,3,CC1(C)OB(c2ccc(N3C[C@H](Cn4cc(CF)nn4)OC3=O)cc2F)OC1(C)C.OC[C@@H]1CC(c2ccc(Br)cn2)=NO1>>O=C1O[C@@H](Cn2cc(CF)nn2)CN1c1ccc(-c2ccc(C3=NO[C@H](CO)C3)nc2)c(F)c1 -US20020049239A1,3,CC[Sn](CC)(CC)CC.O=[N+]([O-])c1cc(Br)c2scnc2c1>>CCc1cc([N+](=O)[O-])cc2ncsc12 -US04623662,2,CC(C)(C)CCN.CC(C)(C)Cc1ccc(C(=O)Cl)cc1>>CC(C)(C)CCNC(=O)c1ccc(CC(C)(C)C)cc1 -US20130203734A1,2,CCCCCCCCc1ccc(S(=O)(=O)Cl)cc1.N[C@H]1CCCCNC1=O>>CCCCCCCCc1ccc(S(=O)(=O)N[C@H]2CCCCNC2=O)cc1 -US20090118296A1,6,COC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1>>O=C(O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1 -US20020123496A1,1,C1CCNCC1.COc1ccc(-c2cc(=O)n(CCO)nc2-c2ccc(OC)cc2)cc1>>COc1ccc(-c2cc(=O)n(CCN3CCCCC3)nc2-c2ccc(OC)cc2)cc1 -US20110166129A1,3,CC1(C)OB(c2ccc(N3CCOCC3)nc2)OC1(C)C.CCOC(=O)c1nc(I)sc1NC(=O)OC(C)(C)C>>CCOC(=O)c1nc(-c2ccc(N3CCOCC3)nc2)sc1NC(=O)OC(C)(C)C -US08263606B2,1,FC1(F)CC1CBr.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCO3>>O=C1N(CC2CC2(F)F)c2ccccc2C12COc1cc3c(cc12)OCCO3 -US20140329858A1,1,N#Cc1ccc(N2C(=O)N[C@H]3CCCC[C@@H]32)cc1C(F)(F)F.OCc1ccc(I)cc1F>>N#Cc1ccc(N2C(=O)N(c3ccc(CO)c(F)c3)[C@H]3CCCC[C@@H]32)cc1C(F)(F)F -US20110092526A1,1,CI.COC(=O)[C@H]1CCC(=O)N1>>COC(=O)[C@H]1CCC(=O)N1C -US04920116,1,CCNCC.O=C(CBr)c1cccc2ccccc12>>CCN(CC)CC(=O)c1cccc2ccccc12 -US04599198,1,BrCc1ccccc1.COC(=O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](OCc1ccccc1)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C -US06638967B2,1,C1CCNC1.COC(=O)c1ccc(C=O)cc1>>COC(=O)c1ccc(CN2CCCC2)cc1 -US07820693B2,2,Nc1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1.O=C(O)CCl>>O=C(CCl)Nc1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1 -US08703805B2,1,CN(C)C(=O)CCl.CS(=O)(=O)c1cccc(-c2ccc(-c3cc(C(F)(F)F)nn3-c3cccc(O)c3)s2)c1>>CN(C)C(=O)COc1cccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3cccc(S(C)(=O)=O)c3)s2)c1 -US20100069384A1,1,C1CCNC1.CCOc1ccc2c(c1)C(C)(c1cc(C=O)ccc1Cl)C(=O)N2>>CCOc1ccc2c(c1)C(C)(c1cc(CN3CCCC3)ccc1Cl)C(=O)N2 -US20150239844A1,9,COc1ccc(C(O)(c2ccc3nccc(/C=C/c4ccccc4)c3c2)c2nccs2)cc1>>COc1ccc(C(c2ccc3nccc(/C=C/c4ccccc4)c3c2)c2nccs2)cc1 -US20120071560A1,1,CC(Br)C(=O)c1cccc(Cl)c1.NC1CCC1>>CC(NC1CCC1)C(=O)c1cccc(Cl)c1 -US20040171623A1,2,COC(=O)c1c(C)[nH]c(C)c1C=O.O=C(Cl)OCc1ccccc1>>COC(=O)c1c(C=O)c(C)n(C(=O)OCc2ccccc2)c1C -US05407961,3,CC(=O)Cl.CC(=O)Nc1ccc2c(c1)CCC2>>CC(=O)Nc1cc2c(cc1C(C)=O)CCC2 -US20120295894A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@H]1CC[C@@H](C)N1>>COC(=O)[C@H]1CC[C@H](C)N1C(=O)OC(C)(C)C -US20150031674A1,6,CCNc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CCOC3CC(N4C(=O)c5ccccc5C4=O)C3)c2n1>>CCNc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CCOC3CC(N)C3)c2n1 -US20120028931A1,4,C#CC=C1CCN(c2ncccc2[N+](=O)[O-])CC1.C[Si](C)(C)N=[N+]=[N-].Nc1ccccc1>>O=[N+]([O-])c1cccnc1N1CCC(=Cc2cn(-c3ccccc3)nn2)CC1 -US20080242698A1,2,NCCC(c1ccccc1)c1ccccc1.O=C(O)CNC(c1ccccc1)c1ccccc1>>O=C(CNC(c1ccccc1)c1ccccc1)NCCC(c1ccccc1)c1ccccc1 -US08026233B2,3,CC(=O)Cn1ncc2cc(Oc3ccc(F)cc3F)c(Br)cc21.C[Mg+]>>CC(C)(O)Cn1ncc2cc(Oc3ccc(F)cc3F)c(Br)cc21 -US08859572B2,1,CN1CCN(S(=O)(=O)CCCCl)CC1.O=C(NC1=Nc2cc(O)ccc2C2=NCCN12)c1cccnc1>>CN1CCN(S(=O)(=O)CCCOc2ccc3c(c2)N=C(NC(=O)c2cccnc2)N2CCN=C32)CC1 -US07589232B2,2,CCCCCCCCC#Cc1ccc(CNCc2ccc(OCC(=O)OC)c(C(=O)OC)c2)cc1.O=C(Cl)CCC1CCCC1>>CCCCCCCCC#Cc1ccc(CN(Cc2ccc(OCC(=O)OC)c(C(=O)OC)c2)C(=O)CCC2CCCC2)cc1 -US20080032998A1,2,C1=C(c2ccccn2)CNCC1.O=C(O)c1cc2ncc(Br)cn2n1>>O=C(c1cc2ncc(Br)cn2n1)N1CCC=C(c2ccccn2)C1 -US04791120,1,BrCCc1ccccc1.CCC(=O)N(c1ccccc1)C1(c2nnc(CC)o2)CCNCC1>>CCC(=O)N(c1ccccc1)C1(c2nnc(CC)o2)CCN(CCc2ccccc2)CC1 -US08445490B2,2,C=CCOc1ccc(CNc2nc(Nc3ccc(C(=O)NCC(=O)O)cc3)nc(OCC(F)(F)F)n2)cc1.C=CCS(N)(=O)=O>>C=CCOc1ccc(CNc2nc(Nc3ccc(C(=O)NCC(=O)NS(=O)(=O)CC=C)cc3)nc(OCC(F)(F)F)n2)cc1 -US20080132477A1,6,C=CCOc1cc(C(=O)OC)cc(C(=O)OC)c1>>C=CCOc1cc(C(=O)O)cc(C(=O)OC)c1 -US08173650B2,2,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)C3CCNCC3)n(C)c2n1.O=C(Cl)C1CC1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)C3CCN(C(=O)C4CC4)CC3)n(C)c2n1 -US20080249137A1,1,CCI.COC(=O)Cc1cc(O)cc(O)c1>>CCOc1cc(O)cc(CC(=O)OC)c1 -US20140142097A1,3,Nc1ncc(Br)cc1C(=O)Nc1ccncc1.O=Cc1cccc(B(O)O)c1>>Nc1ncc(-c2cccc(C=O)c2)cc1C(=O)Nc1ccncc1 -US20090149469A1,1,BrCc1ccccc1.COC(=O)c1cccc(O)c1>>COC(=O)c1cccc(OCc2ccccc2)c1 -US20120309796A1,6,CN(C1CCCCc2c(OCC(=O)OC(C)(C)C)cccc21)S(=O)(=O)c1ccc(-c2cccc(S(C)(=O)=O)c2)cc1>>CN(C1CCCCc2c(OCC(=O)O)cccc21)S(=O)(=O)c1ccc(-c2cccc(S(C)(=O)=O)c2)cc1 -US20100249124A1,3,CC(c1ccc(Br)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.O=C(O)CCc1ccc(B(O)O)cc1>>CC(c1ccc(-c2ccc(CCC(=O)O)cc2)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F -US20110207773A1,2,Nc1ccc(F)cn1.O=C(O)c1cc(-c2ccc(Cl)c(Cl)c2)nc2ccccc12>>O=C(Nc1ccc(F)cn1)c1cc(-c2ccc(Cl)c(Cl)c2)nc2ccccc12 -US20140148430A1,1,Cc1cc(N)nn1CCO.Clc1cc(Br)c2nccn2c1>>Cc1cc(Nc2cc(Cl)cn3ccnc23)nn1CCO -US05057525,6,CCOC(=O)N1CCC(OC)(OC)C(OCC)C1>>CCOC(=O)N1CCC(=O)C(OCC)C1 -US08476449B2,3,CCOC(=O)CN1C(=O)CNC1=S.O=Cc1ccc(-c2cccc(I)c2)o1>>CCOC(=O)CN1C(=O)/C(=C/c2ccc(-c3cccc(I)c3)o2)NC1=S -US05665718,6,CCOC(=O)c1ncn2c1[C@@H]1CCN1C(=O)c1c-2ccc(F)c1F>>O=C(O)c1ncn2c1[C@@H]1CCN1C(=O)c1c-2ccc(F)c1F -US08324186B2,9,N#C[Cu].O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(n3cc(I)ccc3=O)CC2)C1>>N#Cc1ccc(=O)n(C2CCC(N3CC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)c1 -US08927715B2,9,O=C(NC1C2CC3CC(C2)CC1C3)N1CCCC2(Cc3ccccc3C2O)C1>>O=C(NC1C2CC3CC(C2)CC1C3)N1CCCC2(Cc3ccccc3C2)C1 -US05614550,7,CC(C)(C)c1ccc(C(=O)O)cc1[N+](=O)[O-]>>CC(C)(C)c1ccc(CO)cc1[N+](=O)[O-] -US20080004295A1,1,CC(C)N.Cc1ccc(S(=O)(=O)n2ccc3c(Cl)nc(I)nc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(NC(C)C)nc(I)nc32)cc1 -US04812164,1,C#CCO.CC(C)OC(=O)c1cc(-n2c(Cl)nc(C(F)(F)C(F)(F)F)c(F)c2=O)c(F)cc1Cl>>C#CCOc1nc(C(F)(F)C(F)(F)F)c(F)c(=O)n1-c1cc(C(=O)OC(C)C)c(Cl)cc1F -US20090324581A1,5,CC(C)(C)OC(=O)CCNCC(=O)OCc1ccccc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)CCN(CC(=O)OCc1ccccc1)C(=O)OC(C)(C)C -US04564386,2,C#CCN.Cc1cc(C)c(S(=O)(=O)Cl)cc1NS(=O)(=O)C(F)(F)F>>C#CCNS(=O)(=O)c1cc(NS(=O)(=O)C(F)(F)F)c(C)cc1C -US20090312327A1,2,CNC1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)c(Cl)c1.O=C(O)c1ccc(Cl)cn1>>CN(C(=O)c1ccc(Cl)cn1)C1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)c(Cl)c1 -US20030191323A1,2,CC(=O)OC(C)=O.NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCC2CCCCC2)c1>>CC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCC2CCCCC2)c1 -US05215919,7,CCOC(=O)C1CCCCC1=O>>CCOC(=O)C1CCCCC1O -US20030191122A1,2,CC(=O)O.Cc1cn(-c2c(Cl)cc(Br)cc2Br)c(N)c1C#N>>CC(=O)Nc1c(C#N)c(C)cn1-c1c(Cl)cc(Br)cc1Br -US08618094B2,8,C[C@H](c1ccccc1)N1C[C@@](CO)(C(=O)OC(C)(C)C)CC1=O>>C[C@H](c1ccccc1)N1C[C@@](C=O)(C(=O)OC(C)(C)C)CC1=O -US20040147588A1,1,CCOc1cc(C(CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)C(C)Br)c3C2=O)ccc1OC.CNC>>CCOc1cc(C(CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)C(C)N(C)C)c3C2=O)ccc1OC -US20040152747A1,2,CCCC(NC(=O)OC(C)(C)C)C(=O)O.Cc1cnc(N)s1>>CCCC(NC(=O)OC(C)(C)C)C(=O)Nc1ncc(C)s1 -US08501732B2,2,NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O.O=C(Cl)c1cc(F)ccc1F>>O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1cc(F)ccc1F -US08034812B2,2,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.O=C(O)C1=CCCC1>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1NC(=O)C1=CCCC1 -US09018204B1,7,COC(=O)c1cc2cc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)ccc2[nH]1>>OCc1cc2cc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)ccc2[nH]1 -US20010052156A1,6,CCNc1cc(NC(C)=O)ccc1[N+](=O)[O-]>>CCNc1cc(N)ccc1[N+](=O)[O-] -US20140148451A1,1,CCN1CCC(N)CC1.COc1ccc2nc3ccccc3c(Cl)c2c1>>CCN1CCC(Nc2c3ccccc3nc3ccc(OC)cc23)CC1 -US07816395B2,10,C=CCN1C[C@@H](N(Cc2ccccc2C)c2ccc(C#N)c(Cl)c2)CC1=O.O>>Cc1ccccc1CN(c1ccc(C#N)c(Cl)c1)[C@H]1CC(=O)N(CCCO)C1 -US08952005B2,1,CC(C)(C)OC(=O)N1CCC(CO)CC1.O=c1[nH]c2ccc(Br)cc2s1>>CC(C)(C)OC(=O)N1CCC(Cn2c(=O)sc3cc(Br)ccc32)CC1 -US20060172988A1,1,CN(C[C@@H](CC=O)c1ccc(F)cc1)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.OC1CCN(C2CNC2)CC1>>CN(C[C@@H](CCN1CC(N2CCC(O)CC2)C1)c1ccc(F)cc1)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20140329771A1,3,C=CC[C@@H](OC(=O)CCC[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)CC=C)[C@@H](C)COS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)OCC(C)[C@H]2CC=CC[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)CCCC(=O)O2)cc1 -US20110230462A1,1,CCCC[Sn](Cl)(CCCC)CCCC.CNC(=O)c1ccnc(I)c1>>CCCC[Sn](CCCC)(CCCC)c1cc(C(=O)NC)ccn1 -US20090012129A1,6,CCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\C)C(=O)OCC)cc2OCCCC)c1>>CCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\C)C(=O)O)cc2OCCCC)c1 -US20100197681A1,1,Cc1ccc(CN)o1.O=C(Nc1nc2cccc(Br)n2n1)c1cccnc1>>Cc1ccc(CNc2cccc3nc(NC(=O)c4cccnc4)nn23)o1 -US20050245518A1,1,COC(=O)c1ccc(CBr)cc1.CSc1ncc(C#N)c(N)n1>>COC(=O)c1ccc(CNc2nc(SC)ncc2C#N)cc1 -US05536827,1,ClCOCc1ccccc1.O=C1NC(=O)c2c1c1c3cccc(OCc4ccccc4)c3[nH]c1c1[nH]c3c(OCc4ccccc4)cccc3c21>>O=C1c2c(c3c4cccc(OCc5ccccc5)c4[nH]c3c3[nH]c4c(OCc5ccccc5)cccc4c23)C(=O)N1COCc1ccccc1 -US20030212075A1,1,NCCCO.O=C1CCN(Cc2ccccc2)CC1>>OCCCNC1CCN(Cc2ccccc2)CC1 -US20140080798A1,3,C#Cc1ccccc1CC(=O)OC.CC(C)(C)OC(=O)NCc1ccc(Nc2ncc(C(F)(F)F)c(Cl)n2)cc1>>COC(=O)Cc1ccccc1C#Cc1nc(Nc2ccc(CNC(=O)OC(C)(C)C)cc2)ncc1C(F)(F)F -US20120040954A1,4,COc1cc(N)c(C(N)=O)c(OC)c1.Cc1cc(C=O)ccc1OCCO>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCO)c(C)c3)nc2c1 -US04464390,2,CCCCCCCCCCCO.CCCN=C=O>>CCCCCCCCCCCOC(=O)NCCC -US06124287,1,COC(CN)OC.Clc1nc2ccccc2nc1Cl>>COC(CNc1nc2ccccc2nc1Cl)OC -US20100285149A1,6,COc1ccccc1CCC(=O)Nc1sc2c(c1C#N)CCN(C(=O)OC(C)(C)C)C2>>COc1ccccc1CCC(=O)Nc1sc2c(c1C#N)CCNC2 -US20070138131A1,9,Oc1ccc2ncccc2c1>>c1ccc2ncccc2c1 -US08273754B2,6,CC(C)(C)OC(=O)NC1Cc2ccccc2N(c2ccccc2)C1>>NC1Cc2ccccc2N(c2ccccc2)C1 -US20100094000A1,2,CCCCCCCCCCCCCCCC(=O)O.Cc1nn(CC(F)(F)CO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2>>CCCCCCCCCCCCCCCC(=O)OCC(F)(F)Cn1nc(C)c(-c2ccc3c(c2)NC(=O)CO3)c1-c1ccc(F)cc1 -US20080132477A1,7,N#Cc1cccc(C2CC2)c1>>NCc1cccc(C2CC2)c1 -US20150018363A1,1,CI.Cn1c(C(O)C2CC2)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc21>>COC(c1nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc2n1C)C1CC1 -US20040192926A1,2,CN(C)/C=N/c1ncc(C(=O)O)s1.NC1CC1>>CN(C)/C=N/c1ncc(C(=O)NC2CC2)s1 -US07803950B2,2,Cc1cccc(CBr)c1C(=O)Br.OCc1ccccc1>>Cc1cccc(CBr)c1C(=O)OCc1ccccc1 -US20080306096A1,1,CC(C)(C)OC(=O)NCCCI.COc1cc2c(Nc3cc(NC(=O)c4cccc(C(F)(F)F)c4)ccc3C)ncnc2cc1O>>COc1cc2c(Nc3cc(NC(=O)c4cccc(C(F)(F)F)c4)ccc3C)ncnc2cc1OCCCNC(=O)OC(C)(C)C -US04721793,6,COC(=O)C1CN(Cc2ccccc2)C1>>O=C(O)C1CN(Cc2ccccc2)C1 -US04847289,3,C=O.CNC.NS(=O)(=O)c1ccc(S(=O)(=O)CCCc2ccc(O)cc2)s1>>CN(C)Cc1cc(CCCS(=O)(=O)c2ccc(S(N)(=O)=O)s2)ccc1O -US20120295903A1,1,CC(C)(C)OC(=O)C1CCN(CCN)CC1.O=[N+]([O-])c1ccccc1F>>CC(C)(C)OC(=O)C1CCN(CCNc2ccccc2[N+](=O)[O-])CC1 -US08778950B2,2,CC(C)(C)[C@H](N)CO.O=C(O)c1nn(-c2cnccn2)c2c1C[C@H]1C[C@@H]21>>CC(C)(C)[C@@H](CO)NC(=O)c1nn(-c2cnccn2)c2c1C[C@H]1C[C@@H]21 -US08524691B2,6,O=C(O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21>>N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O -US20120094997A1,7,COC(=O)c1ccc([N+](=O)[O-])c(C(=O)NC(C)(C)c2ccccc2)c1>>COC(=O)c1ccc(N)c(C(=O)NC(C)(C)c2ccccc2)c1 -US20150148376A1,6,CCOC(=O)c1ccc2c(n1)CCCC2N(CCc1cc(F)ccc1OCc1ccc(CCc2ccc(C(F)(F)F)cc2)cc1)C(=O)OC(C)(C)C>>CCOC(=O)c1ccc2c(n1)CCCC2NCCc1cc(F)ccc1OCc1ccc(CCc2ccc(C(F)(F)F)cc2)cc1 -US20150031668A1,1,CI.O=C(N[C@]1(c2ccc(OC(F)(F)F)c(F)c2)CCOc2cccnc21)c1cc(Br)c[nH]1>>Cn1cc(Br)cc1C(=O)N[C@]1(c2ccc(OC(F)(F)F)c(F)c2)CCOc2cccnc21 -US20090062348A1,8,OCc1cc2ccc(OCC3CC3)cc2[nH]1>>O=Cc1cc2ccc(OCC3CC3)cc2[nH]1 -US20120244120A1,6,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCc3ccnc(NC(=O)C(C)(C)N(C)C(=O)OC(C)(C)C)c3)c3ccccc23)cc1>>CNC(C)(C)C(=O)Nc1cc(COc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1 -US04501746,2,CC(NC1CCCCC1)c1cccnc1.CCCCSCC(=O)O>>CCCCSCC(=O)N(C1CCCCC1)C(C)c1cccnc1 -US06855512B2,3,C#Cc1ccc(C2(N(Cc3ccccc3)Cc3ccccc3)CC2)cc1.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(C#Cc2ccc(C3(N(Cc4ccccc4)Cc4ccccc4)CC3)cc2)cc1 -US20090036708A1,6,C=CCCCCC[C@@H](NC(=O)OC(C)(C)C)C(=O)OCC>>C=CCCCCC[C@@H](NC(=O)OC(C)(C)C)C(=O)O -US04971993,2,N[C@@H](CC(Cc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1.O=S(=O)(Cl)c1ccccc1>>O=C(O)C(Cc1ccccc1)C[C@H](NS(=O)(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1 -US20070259860A1,1,CC(C)(C)OC(=O)NCCC=O.CC(N)c1nnn(-c2cccc(Cl)c2)n1>>CC(NCCCNC(=O)OC(C)(C)C)c1nnn(-c2cccc(Cl)c2)n1 -US06689806B1,8,OCc1ccc2[nH]ccc2c1>>O=Cc1ccc2[nH]ccc2c1 -US07858640B2,6,CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(F)cc1Cl>>CCc1nc2c(F)ccc(OCC(=O)O)c2c(OC(F)F)c1Cc1ccc(F)cc1Cl -US20100216762A1,9,FC(F)(F)c1cccc(COc2ccc(Br)cn2)c1.N#C[Cu]>>N#Cc1ccc(OCc2cccc(C(F)(F)F)c2)nc1 -US20100331312A1,6,COc1ccc(COc2ccc(CCN3CCC[C@H]3C)cc2Cl)cc1>>C[C@@H]1CCCN1CCc1ccc(O)c(Cl)c1 -US20080234255A1,1,CCCCNCCC(=O)OC(C)(C)C.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CCCCN(CCC(=O)OC(C)(C)C)c1nc(Cl)ncc1[N+](=O)[O-] -US20150232481A1,3,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)O)c(C)nc3cc(COCc4c(F)cc(F)cc4O[C@@H](C)CC=C)nn23)CC1>>Cc1nc2cc3nn2c(c1[C@H](OC(C)(C)C)C(=O)O)N1CCC(C)(CC1)OCC=CC[C@H](C)Oc1cc(F)cc(F)c1COC3 -US20070027178A1,4,CSc1c(Cl)cccc1NN.O=C1CCNCC1>>CSc1c(Cl)ccc2c3c([nH]c12)CCNC3 -US20080045537A1,2,CN(Cc1nc2c(N)cccc2[nH]1)C1CCCc2cccnc21.O=C(O)c1cccnc1>>CN(Cc1nc2c(NC(=O)c3cccnc3)cccc2[nH]1)C1CCCc2cccnc21 -US04617394,1,CC(I)CCCN1C(=O)c2ccccc2C1=O.COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(N)c2n1>>COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(NC(C)CCCN3C(=O)c4ccccc4C3=O)c2n1 -US08759366B2,7,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C=O)s2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(CO)s2)c1 -US20120220609A1,7,CC(=O)Cc1ccc(-c2ccc(Br)cc2)cc1>>CC(O)Cc1ccc(-c2ccc(Br)cc2)cc1 -US20150080393A1,6,CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccc(C)c(C)c5)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OCc1ccccc1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccc(C)c(C)c5)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1 -US20110212940A1,7,O=[N+]([O-])c1cc(Cc2ccccc2)ccc1O>>Nc1cc(Cc2ccccc2)ccc1O -US07105671B2,2,CS(=O)(=O)c1ccc(C(CC2CCC(=O)CC2)C(=O)O)cc1Cl.Nc1cnccn1>>CS(=O)(=O)c1ccc(C(CC2CCC(=O)CC2)C(=O)Nc2cnccn2)cc1Cl -US20120101134A1,6,CCOC(=O)CCCc1cccc(-c2nnc(-c3ccc(OC(C)C)c(C#N)c3)s2)c1CC>>CCc1c(CCCC(=O)O)cccc1-c1nnc(-c2ccc(OC(C)C)c(C#N)c2)s1 -US20130274260A1,2,NCCc1c[nH]c2ccc(Cl)cc12.O=C(O)c1ccc(Cc2cccc(F)c2)cn1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(F)c2)cn1 -US05821240,2,C1CCNC1.Nc1c(Cl)cc(Nc2ncnc3cnc(N[C@@H]4CC[C@@H](C(=O)O)CC4)nc23)cc1Cl>>Nc1c(Cl)cc(Nc2ncnc3cnc(N[C@@H]4CC[C@@H](C(=O)N5CCCC5)CC4)nc23)cc1Cl -US20080255147A1,1,C1CNCCN1.COc1ccccc1-c1nc(Cl)ns1>>COc1ccccc1-c1nc(N2CCNCC2)ns1 -US04490373,6,CC(C)(C)OC(=O)CNC(=O)c1nc2cc(Cl)ccc2o1>>O=C(O)CNC(=O)c1nc2cc(Cl)ccc2o1 -US20050182025A1,1,CC(C)CCCBr.Cc1cc(N=CN(C)C)c(C)cc1O>>Cc1cc(OCCCC(C)C)c(C)cc1N=CN(C)C -US20070010511A1,1,CC1(C)CC(=O)N(COCC[Si](C)(C)C)c2c(CCl)cccc21.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2cccc3c2N(COCC[Si](C)(C)C)C(=O)CC3(C)C)cc1 -US05075301,9,[N-]=[N+]=NCCn1c(=O)[nH]c2ccccc21>>NCCn1c(=O)[nH]c2ccccc21 -US08372840B2,1,O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1cccc(Br)c1.c1ccc(N2CCNCC2)cc1>>O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1cccc(N2CCN(c3ccccc3)CC2)c1 -US06846826B2,1,BrCCBr.Oc1ccccc1Cl>>Clc1ccccc1OCCBr -US20150031685A1,7,O=C(CBr)c1ccc(OC(F)(F)F)cc1>>O[C@H](CBr)c1ccc(OC(F)(F)F)cc1 -US20050042255A1,7,COc1ccc(C(=O)C2CCC2)cc1>>COc1ccc(CC2CCC2)cc1 -US06982348B2,2,CC(C)(C)c1cccc(CC(N)C(O)c2cccc(Cl)c2)c1.O=C(O)c1ccc(F)c2ccccc12>>CC(C)(C)c1cccc(CC(NC(=O)c2ccc(F)c3ccccc23)C(O)c2cccc(Cl)c2)c1 -US04206309,1,C=COCCCl.CN1CC(=O)NC1=O>>C=COCCN1C(=O)CN(C)C1=O -US20050101644A1,1,CCN.O=C1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1>>CCNC1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1 -US20140155262A1,1,O=C(CBr)c1ccc(Oc2ccc(Cl)cc2)cc1C(F)(F)F.c1nc[nH]n1>>O=C(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1C(F)(F)F -US06762205B1,1,N#Cc1ccc(N)cc1.O=Cc1ccsc1>>N#Cc1ccc(NCc2ccsc2)cc1 -US08916560B2,6,COCC1CCCN(c2nc3cc(C(=O)OC)ccc3nc2-c2ccc(F)cc2)C1>>COCC1CCCN(c2nc3cc(C(=O)O)ccc3nc2-c2ccc(F)cc2)C1 -US09150555B2,6,CCOC(=O)c1cnn(-c2ncc(Cl)cc2F)c1C>>Cc1c(C(=O)O)cnn1-c1ncc(Cl)cc1F -US20020160996A1,1,CC(=Cc1ccc(C)cc1)CBr.Cc1cc(O)c(C)c(C)c1NC=O>>CC(=Cc1ccc(C)cc1)COc1cc(C)c(NC=O)c(C)c1C -US20100010222A1,8,CCOC(=O)CC[C@H](CO)NC(=O)OC(C)(C)C>>CCOC(=O)CC[C@H](C=O)NC(=O)OC(C)(C)C -US06969725B2,1,CCO[C@@H](Cc1ccc(O)cc1C(F)(F)F)C(=O)OC.Cc1oc(-c2ccccc2)nc1CCl>>CCO[C@@H](Cc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1C(F)(F)F)C(=O)OC -US05856326,1,CCCC[C@H]1CN(C(=O)c2cccc3ccccc23)CCN1.O=Cc1cccnc1>>CCCC[C@H]1CN(C(=O)c2cccc3ccccc23)CCN1Cc1cccnc1 -US20140249157A1,2,CC(=O)NN.S=C=Nc1ccncc1Br>>CC(=O)NNC(=S)Nc1ccncc1Br -US20140303161A1,3,CN(C)C(C)(C)C=O.Cc1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1C[C@@H]1CCCN1C(=O)CC#N>>Cc1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1C[C@@H]1CCCN1C(=O)C(C#N)=CC(C)(C)N(C)C -US08327467B2,6,CC(C)(C)OC(=O)c1ccc(N2CCc3ccccc32)cc1Nc1ccc2sccc2c1>>O=C(O)c1ccc(N2CCc3ccccc32)cc1Nc1ccc2sccc2c1 -US20090209571A1,6,COC(=O)Cc1ccccc1-c1cc2ccccc2s1>>O=C(O)Cc1ccccc1-c1cc2ccccc2s1 -US20150005315A1,6,COc1cc(Oc2cccc(C)c2)ccc1C(=O)O>>Cc1cccc(Oc2ccc(C(=O)O)c(O)c2)c1 -US20110086860A1,7,O=[N+]([O-])c1cc(Br)ccc1-n1ccnc1>>Nc1cc(Br)ccc1-n1ccnc1 -US20080188521A1,9,Fc1ccc(-c2cc(Cl)nc3cc(CBr)ccc23)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc2c(-c3ccc(F)cc3)cc(Cl)nc2c1 -US08106052B2,1,CC(C)=CCC/C(C)=C/CBr.N#Cc1nc2ccc(O)cc2s1>>CC(C)=CCC/C(C)=C/COc1ccc2nc(C#N)sc2c1 -US20150236274A1,1,Brc1cc(Oc2ccccc2)cc(Oc2ccccc2)c1.c1ccc2c(c1)Nc1ccccc1O2>>c1ccc(Oc2cc(Oc3ccccc3)cc(N3c4ccccc4Oc4ccccc43)c2)cc1 -US04789683,6,CCN1CCCC1CNC(=O)c1c(OC)c(Cl)cc(Cl)c1OC>>CCN1CCCC1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC -US20050054629A1,1,BrCCCCCBr.CC=Cc1oc(CO)cc(=O)c1O>>CC=Cc1oc(CO)cc(=O)c1OCCCCCBr -US20050085473A1,1,CCOC(=O)CBr.O=Cc1c(Cl)cc(O)cc1Cl>>CCOC(=O)COc1cc(Cl)c(C=O)c(Cl)c1 -US05430042,6,COCCCOc1c(Cl)ccnc1C>>Cc1nccc(Cl)c1OCCCO -US20150183801A1,3,COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1C#N.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1>>COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)cc1C#N -US20140350011A1,7,CC12CCC(Nc3c(Cl)cnc4[nH]c(-c5ccc(N6CCOCC6)cc5)nc34)(CC1=O)C2(C)C>>CC12CCC(Nc3c(Cl)cnc4[nH]c(-c5ccc(N6CCOCC6)cc5)nc34)(CC1O)C2(C)C -US06432993B1,2,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(Oc3ccccc3)cc2)ccc1N.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(Oc3ccccc3)cc2)ccc1NC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1 -US07262201B1,1,COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1O.ClCCCBr>>COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCCCCl -US20150225397A1,6,C[C@H]1[C@@H]2CCc3cncnc3[C@@]2(c2ccccc2)CCC12OCCO2>>C[C@@H]1C(=O)CC[C@]2(c3ccccc3)c3ncncc3CC[C@@H]12 -US20100036054A1,9,BrC(Br)(Br)Br.OCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCBr -US20120077812A1,3,CC(C)OC(=O)N1CCC(COc2ccc(Br)cc2)CC1.CSc1ccc(B(O)O)cc1>>CSc1ccc(-c2ccc(OCC3CCN(C(=O)OC(C)C)CC3)cc2)cc1 -US20090247567A1,1,CN(C(=O)c1cc2c(s1)-c1ccc(NC(=O)CCl)cc1OCC2)c1ccccc1Cl.CN1CCNCC1>>CN1CCN(CC(=O)Nc2ccc3c(c2)OCCc2cc(C(=O)N(C)c4ccccc4Cl)sc2-3)CC1 -US20090221555A1,1,CN(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.Nc1ccc2c(c1)CCN(C(=O)C1COCCO1)CC2>>CN(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2)CCN(C(=O)C2COCCO2)CC3)ncc1Cl -US20050137162A1,3,Brc1nccs1.COC(=O)c1cc(Br)cc2c1OC(c1ccccc1)(c1ccccc1)O2>>COC(=O)c1cc(-c2nccs2)cc2c1OC(c1ccccc1)(c1ccccc1)O2 -US20110237581A1,6,CCOC(OCC)c1ccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccc(C(=O)N(C)C)cc2)cc1>>CN(C)C(=O)c1ccc(C2c3n[nH]c(=O)c4cccc(c34)NC2c2ccc(C=O)cc2)cc1 -US20040180934A1,6,CCOC(=O)CC1CCCn2c1c(-c1ccc(Cl)cc1)c1c(S(C)=O)cccc12>>CS(=O)c1cccc2c1c(-c1ccc(Cl)cc1)c1n2CCCC1CC(=O)O -US20050176775A1,6,COC(=O)c1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)cc1>>Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1Cc1ccc(C(=O)O)cc1 -US20110086843A1,6,COC(=O)[C@H](CO)NS(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)s1>>CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)N[C@@H](CO)C(=O)O)s2)s1 -US20140155385A1,2,CCc1ccnc(NC(=O)c2ccc(-c3nc([C@@H]4CCCN4)n4ccnc(N)c34)cc2)c1.COC/C=C/C(=O)O>>CCc1ccnc(NC(=O)c2ccc(-c3nc([C@@H]4CCCN4C(=O)/C=C/COC)n4ccnc(N)c34)cc2)c1 -US20030220323A1,6,COC(=O)CN1CCN(C(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc2N)CC1>>Nc1ccccc1C(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(CC(=O)O)CC1 -US07851615B2,2,CCCCCCCCCCCCCC(=O)O.COc1ccc(C(OC(c2ccccc2)C2CC(O)CN2C(=O)CCCCCN)c2ccc(OC)cc2)cc1>>CCCCCCCCCCCCCC(=O)NCCCCCC(=O)N1CC(O)CC1C(OC(c1ccc(OC)cc1)c1ccc(OC)cc1)c1ccccc1 -US08143261B2,1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.Nc1nc2nc(SCc3cccc(F)c3F)nc(Cl)c2s1>>CC(C)(C)OC(=O)N1CC[C@@H](Nc2nc(SCc3cccc(F)c3F)nc3nc(N)sc23)C1 -US20050032838A1,2,CSc1cccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@H](N)CC2)c1.O=C(O)C1CC1>>CSc1cccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@H](NC(=O)C3CC3)CC2)c1 -US20090312342A1,2,COC(=O)C[C@@H](O)C(=O)O.O=C(OCc1ccccc1)N1CCNCC1>>COC(=O)C[C@@H](O)C(=O)N1CCN(C(=O)OCc2ccccc2)CC1 -US20080275035A1,1,CI.[N-]=[N+]=NCC(O)Cn1cc([N+](=O)[O-])nc1Cl>>COC(CN=[N+]=[N-])Cn1cc([N+](=O)[O-])nc1Cl -US20120178736A1,1,CNC1CCN(C(C)C)CC1.Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CBr)n(C)c2n1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN(C)C3CCN(C(C)C)CC3)n(C)c2n1 -US20100048636A1,2,CC1(CC(CO)NC(=O)OCc2ccccc2)CCCCC1.CS(=O)(=O)Cl>>CC1(CC(COS(C)(=O)=O)NC(=O)OCc2ccccc2)CCCCC1 -US20100273786A1,2,C1CCNC1.CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)O)c2C1)Cc1cc(F)c(F)cc1F>>CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)N3CCCC3)c2C1)Cc1cc(F)c(F)cc1F -US06492403B1,1,COC(=S)c1cc(N)c(C)s1.OB(O)c1ccc(-c2ccccc2)c(F)c1>>COC(=S)c1cc(Nc2ccc(-c3ccccc3)c(F)c2)c(C)s1 -US20030166635A1,1,CCI.O=[N+]([O-])C=C1NCCC1Cc1ccc(Cl)nc1>>CCN1CCC(Cc2ccc(Cl)nc2)C1=C[N+](=O)[O-] -US20100222326A1,2,CC[C@H](N)C(N)=O.O=C(O)CNCc1ccccc1>>CC[C@H](NC(=O)CNCc1ccccc1)C(N)=O -US20090215759A1,1,COc1cc(N)ccc1-n1cnc(C)c1.Cc1cc(N2CCCCC2)nc(Cl)n1>>COc1cc(Nc2nc(C)cc(N3CCCCC3)n2)ccc1-n1cnc(C)c1 -US20050038035A1,1,CC(C)(C)OC(=O)Nc1nc(CCN)cs1.O=[N+]([O-])c1ccc(Cl)nc1>>CC(C)(C)OC(=O)Nc1nc(CCNc2ccc([N+](=O)[O-])cn2)cs1 -US09051325B2,1,CN1c2cc(Cl)nc(=O)n2CC1(C)C.OCc1cc(F)c(Oc2ccc(F)nc2)c(F)c1>>CN1c2cc(OCc3cc(F)c(Oc4ccc(F)nc4)c(F)c3)nc(=O)n2CC1(C)C -US06011044,1,Cc1ccccc1-n1ccc2c(Cl)nc3c(OC(F)(F)F)cccc3c21.NCCCO>>Cc1ccccc1-n1ccc2c(NCCCO)nc3c(OC(F)(F)F)cccc3c21 -US07217697B2,1,BrCc1ccccc1.CC(=O)OC[C@H]1O[C@@H](Oc2nn(CCO)c(C(C)C)c2Cc2ccccc2O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@H]1O[C@@H](Oc2nn(CCO)c(C(C)C)c2Cc2ccccc2OCc2ccccc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US20140294898A1,6,COC(=O)[C@H](Cc1ccc(F)c(Cl)c1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)c(Cl)c1)C(=O)O -US20040180947A1,2,CC(=O)O.Nc1nc(Br)ccc1[N+](=O)[O-]>>CC(=O)Nc1nc(Br)ccc1[N+](=O)[O-] -US20100256097A1,1,CN(Cc1cccc(Br)n1)C(=O)OC(C)(C)C.NC(=O)c1cc(-c2ccc(F)cc2)sc1N>>CN(Cc1cccc(Nc2sc(-c3ccc(F)cc3)cc2C(N)=O)n1)C(=O)OC(C)(C)C -US05314640,3,C#Cc1ccc(CCC)cc1.N#Cc1ccc(I)cc1F>>CCCc1ccc(C#Cc2ccc(C#N)c(F)c2)cc1 -US20050065118A1,6,COC(=O)c1ccc(CN(c2ccc(Cl)c(Cl)c2)c2nnc(-c3cccc(Oc4cccc(C(F)(F)F)c4)c3)s2)cc1>>O=C(O)c1ccc(CN(c2ccc(Cl)c(Cl)c2)c2nnc(-c3cccc(Oc4cccc(C(F)(F)F)c4)c3)s2)cc1 -US06034275,3,C=CCN(C)C/C=C/COc1ccc(C(C)=O)cc1F.CC(C)=CC=O>>C=CCN(C)C/C=C/COc1ccc(C(=O)CC(O)C=C(C)C)cc1F -US20120225868A1,2,CC1(C(=O)O)COC1.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1>>CC1(C(=O)N[C@@H]2CC[C@@H](CCN3CCC(c4cccc5c4OCO5)CC3)CC2)COC1 -US04753950,1,BrCc1ccccc1.Nc1c2c(nc3sccc13)CCCC2=O>>O=C1CCCc2nc3sccc3c(NCc3ccccc3)c21 -US20030092712A1,1,COC(=O)c1ccc(C)c(NC(=O)CCc2c(Br)cc(OC)cc2Br)c1>>COC(=O)c1ccc(C)c(N2C(=O)CCc3c(Br)cc(OC)cc32)c1 -US20060122234A1,1,CC(C)(C)OC(=O)CBr.COC(=O)c1ccc(-c2cc[nH]n2)s1>>COC(=O)c1ccc(-c2ccn(CC(=O)OC(C)(C)C)n2)s1 -US07115635B2,2,CC(=O)c1ccc(OCCC(=O)O)cc1.NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>CC(=O)c1ccc(OCCC(=O)NC2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)cc1 -US05506256,8,COc1ccc(OCC(O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCC23CC4CC(CC(C4)C2)C3)cc1>>COc1ccc(OCC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCC23CC4CC(CC(C4)C2)C3)cc1 -US20150152047A1,1,CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(COS(C)(=O)=O)c(C(F)(F)F)c1.NCCCN>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CNCCCN)c(C(F)(F)F)c1 -US20120132870A1,1,CC1CNCCN1.O=C(c1ccccc1)c1ccc(F)cc1>>CC1CN(c2ccc(C(=O)c3ccccc3)cc2)CCN1 -US20030199578A1,2,Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12.O=C(Cl)C1CCC1>>O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)C1CCC1 -US20120309754A1,7,O=Cc1ccccc1[N+](=O)[O-]>>Nc1ccccc1C=O -US20050239832A1,6,CCc1ccc2c(c1)C(NCC(O)C(Cc1cc(F)cc(F)c1)NC(=O)OC(C)(C)C)=C(O)CO2>>CCc1ccc2c(c1)C(NCC(O)C(N)Cc1cc(F)cc(F)c1)=C(O)CO2 -US07790720B2,1,CC1CCCN1.COC(=O)c1oc(-c2ccc(OCCCCl)cc2)nc1CNCc1ccccc1>>COC(=O)c1oc(-c2ccc(OCCCN3CCCC3C)cc2)nc1CNCc1ccccc1 -US08093264B2,7,O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4cn(CCN5CCCC5)cn4)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(-c4cn(CCN5CCCC5)cn4)sc23)c(F)c1 -US20070021454A1,1,BrCC1CCC1.C[C@H]1C[C@]2(CCN1)C(N[C@H]1CCCC[C@@H]1F)=NC(=O)N2c1cccc(F)c1>>C[C@H]1C[C@]2(CCN1CC1CCC1)C(N[C@@H]1CCCC[C@H]1F)=NC(=O)N2c1cccc(F)c1 -US20090209522A1,1,COc1nc(NCCO[Si](C)(C)C(C)(C)C)nc(OC)c1NC(=O)c1csc(Cl)n1.Cc1ccc(C(C)C)cc1O>>COc1nc(NCCO[Si](C)(C)C(C)(C)C)nc(OC)c1NC(=O)c1csc(Oc2cc(C(C)C)ccc2C)n1 -US20060211739A1,1,BrCc1cccnc1.FC(F)(F)c1cccc(-c2nnn[nH]2)c1I>>FC(F)(F)c1cccc(-c2nnnn2Cc2cccnc2)c1I -US20150065464A1,1,CCOP(OCC)OCC.O=[N+]([O-])c1cccc(CBr)c1>>CCOP(=O)(Cc1cccc([N+](=O)[O-])c1)OCC -US05191084,2,CC(=O)OC(C)=O.COc1ccc(C2CC(=O)NN2C)cc1OC1CCCC1>>COc1ccc(C2CC(=O)N(C(C)=O)N2C)cc1OC1CCCC1 -US08278325B2,1,CCCCOC(=O)c1nc(Cl)c2ccccc2c1O.COc1ccccc1O>>CCCCOC(=O)c1nc(Oc2ccccc2OC)c2ccccc2c1O -US20120283297A1,6,CCOC(=O)CCn1ncc2cc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)ccc21>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(cnn4CCC(=O)O)c3)no2)cc1Cl -US06162824,8,OCC1(c2ccccc2)c2ccccc2-c2ccccc21>>O=CC1(c2ccccc2)c2ccccc2-c2ccccc21 -US04136116,7,Cc1cccc2c(=O)c3ccccc3ccc12>>Cc1cccc2c1C=Cc1ccccc1C2O -US03932496,3,C#C.CCCCC(C)(C)C=O>>C#CC(O)C(C)(C)CCCC -US07833632B2,3,Clc1ccc(-c2ccc3c(c2)nc(-c2ccccc2)n3-c2ccccc2)cc1.OB(O)c1ccc2c(-c3ccccc3)c3ccccc3c(-c3ccccc3)c2c1>>c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4ccc(-c5ccc6c(c5)nc(-c5ccccc5)n6-c5ccccc5)cc4)ccc23)cc1 -US06004977,6,COc1ccc2c(c1)CN(Nc1ccncc1)C2>>Oc1ccc2c(c1)CN(Nc1ccncc1)C2 -US05594135,2,CCCN.COC(=O)[C@@H]1CSCc2c(O)cc(OC)c(C)c2C(=O)OCCCCC(=S)N1>>CCCNC(=O)[C@@H]1CSCc2c(O)cc(OC)c(C)c2C(=O)OCCCCC(=S)N1 -US05866717,1,COCCOCCl.O=C(N[C@@H](Cc1ccccc1)C(=O)NCCO)OCc1ccccc1>>COCCOCOCCNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 -US20110112097A1,1,CC1(C)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O.COC(=O)c1ccc(Cc2ccccc2CBr)cc1>>COC(=O)c1ccc(Cc2ccccc2CN2C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1 -US20050272744A1,1,BrCc1ccccc1Br.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(Cc2ccccc2Br)CC1 -US20100273806A1,3,CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(Br)cc(OC(F)(F)F)c4)n3)cc21.OB(O)c1cccnc1>>CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(OC(F)(F)F)cc(-c5cccnc5)c4)n3)cc21 -US20140194476A1,1,BrCc1ccccc1.O=c1cc(CNS(=O)(=O)c2ccccc2)oc(CO)c1O>>O=c1cc(CNS(=O)(=O)c2ccccc2)oc(CO)c1OCc1ccccc1 -US20090286974A1,2,Clc1ccc2nc(N3CCNCC3)sc2c1.O=C(Cl)CCl>>O=C(CCl)N1CCN(c2nc3ccc(Cl)cc3s2)CC1 -US05733910,9,COC(=O)c1nc2cc(Cl)ccc2c(Cl)c1C(=O)OC>>COC(=O)c1cc2ccc(Cl)cc2nc1C(=O)OC -US07291631B2,2,Cc1cnc(CN(CCCCN)Cc2nccc3ccccc23)c(C)c1.O=C(Cl)c1cccc2[nH]cnc12>>Cc1cnc(CN(CCCCNC(=O)c2cccc3[nH]cnc23)Cc2nccc3ccccc23)c(C)c1 -US05334740,7,COCOC1CC2=CC(=O)OCC2C2OC(C)(C)OC12>>COCOC1CC2=CC(O)OCC2C2OC(C)(C)OC12 -US06025323,7,CC1C(=O)CCC(C)(C)C1=O>>CC1CC(C)(C)CCC1=O -US06699879B1,1,COc1ccc([N+](=O)[O-])cc1CBr.C[S-]>>COc1ccc([N+](=O)[O-])cc1CSC -US09040538B2,1,Cc1cc(O)nc(S)n1.Cn1cnc(CCl)c1Cl>>Cc1cc(O)nc(SCc2ncn(C)c2Cl)n1 -US06586441B2,3,CCCC[Sn](CCCC)(CCCC)c1cnccn1.CSc1nc(N)nc(Br)c1C#N>>CSc1nc(N)nc(-c2cnccn2)c1C#N -US20090286828A1,6,CN(C)C(C)(CO[Si](C)(C)C(C)(C)C)C(NC(=O)c1cc(C(F)(F)F)nc2ccccc12)c1ccccc1>>CN(C)C(C)(CO)C(NC(=O)c1cc(C(F)(F)F)nc2ccccc12)c1ccccc1 -US07772253B2,2,CCOc1cc(CN2CCC(N)CC2)ccc1Cl.CN(C)c1ccc(C(=O)O)cn1>>CCOc1cc(CN2CCC(NC(=O)c3ccc(N(C)C)nc3)CC2)ccc1Cl -US08975254B2,7,C/C(N)=C\c1ccc(-c2ccc(Cl)c(Cl)c2)o1>>CC(N)Cc1ccc(-c2ccc(Cl)c(Cl)c2)o1 -US08722702B2,2,Nc1ccc(Cc2cn(S(=O)(=O)c3ccccc3)c3ncccc23)cn1.O=C=Nc1cccc(F)c1>>O=C(Nc1cccc(F)c1)Nc1ccc(Cc2cn(S(=O)(=O)c3ccccc3)c3ncccc23)cn1 -US20080171737A1,1,CCNCCO.O=S1(=O)C(CCCBr)Oc2ccccc2N1c1ccccc1>>CCN(CCO)CCCC1Oc2ccccc2N(c2ccccc2)S1(=O)=O -US20130158019A1,6,COC(=O)c1cccc(CNC(=O)[C@H]2CCCN(c3ccnc(Nc4cc(OC)c(OC)c(OC)c4)n3)C2)c1>>COc1cc(Nc2nccc(N3CCC[C@H](C(=O)NCc4cccc(C(=O)O)c4)C3)n2)cc(OC)c1OC -US05198449,1,BrCc1ccc2ccccc2c1.Fc1ccc(C(Nc2ccc(F)c(F)c2)C2CCNCC2)cc1>>Fc1ccc(C(Nc2ccc(F)c(F)c2)C2CCN(Cc3ccc4ccccc4c3)CC2)cc1 -US20150266895A1,3,CC(C)(C)OC(=O)Nc1cc(Cl)cc(Cl)n1.CN(C)C=O>>CC(C)(C)OC(=O)Nc1cc(Cl)c(C=O)c(Cl)n1 -US20060014800A1,1,C=C(c1ccc(CO)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C.O=C1CSC(=O)N1>>C=C(c1ccc(CN2C(=O)CSC2=O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C -US09156829B2,2,Cc1ccc(-n2ccnn2)c(C(=O)O)c1.N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1>>Cc1ccc(-n2ccnn2)c(C(=O)N[C@H]2CCC[C@@H]2Nc2cnc(C(F)(F)F)cn2)c1 -US20120149721A1,2,COCC(=O)Cl.Cc1[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc2c1C(=O)N[C@@H]1CCNC1>>COCC(=O)N1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C1 -US08399465B2,1,Clc1nc2ccccc2s1.Oc1ccc2cc[nH]c2c1>>c1ccc2sc(Oc3ccc4cc[nH]c4c3)nc2c1 -US20110257151A1,2,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(N)c1)N2.O=C(Cl)N1CCOCC1>>CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(NC(=O)N3CCOCC3)c1)N2 -US20110282096A1,2,CCCCCCOC(C)(CO)OCCCCCC.CCOS(=O)Cl>>CCCCCCOC(C)(COS(=O)OCC)OCCCCCC -US04946961,1,C#CCBr.O=c1[nH]c2cc(-n3nc4c([n+]3[O-])CCCC4)c(F)cc2s1>>C#CCn1c(=O)sc2cc(F)c(-n3nc4c([n+]3[O-])CCCC4)cc21 -US05919936,2,CN1CCC(c2c[nH]c3ccc(N)nc23)CC1.N#Cc1ccc(C(=O)Cl)cc1>>CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccc(C#N)cc4)nc23)CC1 -US07241785B2,1,COC(=O)Cc1cn(C)nc1O.Cc1oc(-c2ccccc2)nc1COc1cc(CCl)on1>>COC(=O)Cc1cn(C)nc1OCc1cc(OCc2nc(-c3ccccc3)oc2C)no1 -US08017782B2,2,CC(C)C(=O)Cl.CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(OCCCCN)c(OCC)c1>>CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(OCCCCNC(=O)C(C)C)c(OCC)c1 -US20090105252A1,1,CC(c1ccc(Br)cc1)N1CCOCC1.Cc1ncc(-c2nc(N)ncc2F)n1C1CCOCC1>>Cc1ncc(-c2nc(Nc3ccc(C(C)N4CCOCC4)cc3)ncc2F)n1C1CCOCC1 -US20120245137A1,1,CC1(COS(C)(=O)=O)CCC(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1.[N-]=[N+]=[N-]>>CC1(CN=[N+]=[N-])CCC(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 -US20030162795A1,3,Brc1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 -US05347039,7,CCN(CC)C(=O)CC(=O)CC(O)c1ccccc1>>CCN(CC)C(=O)CC(O)CC(O)c1ccccc1 -US20150133428A1,3,CC(C)(C)OC(=O)N1Cc2c(C(N)=O)c(I)nn2CC1C1CC1.OB(O)c1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)N1Cc2c(C(N)=O)c(-c3ccc(F)c(Cl)c3)nn2CC1C1CC1 -US20110212930A1,9,COc1ccc(-n2nc(Br)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1>>COc1ccc(-n2ncc3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1 -US06350749B1,1,Cc1ccc(F)cc1C1CC(=O)c2c(C)cnnc2C1.N=C(N)NN>>Cc1ccc(F)cc1C1CC(=NNC(=N)N)c2c(C)cnnc2C1 -US20120114600A1,2,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3ccc(N)cc3F)c(F)c2)c[nH]1)C(C)C.C[C@@H]1CN(C(=O)[C@H]2CC2(C)C)CCN1c1ccc(C(=O)O)cn1>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3ccc(NC(=O)c4ccc(N5CCN(C(=O)[C@H]6CC6(C)C)C[C@H]5C)nc4)cc3F)c(F)c2)c[nH]1)C(C)C -US20120178736A1,4,CC(F)(F)C(=O)O.Cn1c(CN2CCC(C3COC3)CC2)nc2c(N3CCOCC3)nc(Nc3ccccc3N)nc21>>Cn1c(CN2CCC(C3COC3)CC2)nc2c(N3CCOCC3)nc(-n3c(C(C)(F)F)nc4ccccc43)nc21 -US20100112090A1,1,CNC.COc1cc(Cl)c(Nc2nc(Cl)nc(OC)c2[N+](=O)[O-])cc1OCc1c(OC)ccc(F)c1F>>COc1cc(Cl)c(Nc2nc(N(C)C)nc(OC)c2[N+](=O)[O-])cc1OCc1c(OC)ccc(F)c1F -US08143280B2,1,CC(c1ccc(O)cc1Cl)C(O)(c1ccc(=O)n(C)c1)C(F)(F)F.N#Cc1ccc(F)c(Cl)c1>>CC(c1ccc(Oc2ccc(C#N)cc2Cl)cc1Cl)C(O)(c1ccc(=O)n(C)c1)C(F)(F)F -US06821980B1,1,CCOc1cc(Cc2cnc(N)nc2N)cc(OCC)c1-c1ccc(C=O)cc1.NCC(F)(F)F>>CCOc1cc(Cc2cnc(N)nc2N)cc(OCC)c1-c1ccc(CNCC(F)(F)F)cc1 -US04904691,6,COC(=O)CC(O)CC(O)/C=C/C1=C(c2ccc(F)cc2)C=C(c2ccccc2)C12CCCC2>>O=C(O)CC(O)CC(O)/C=C/C1=C(c2ccc(F)cc2)C=C(c2ccccc2)C12CCCC2 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.Oc1ccc(F)c(C(F)(F)F)c1>>CC#CCOc1cc(Oc2ccc(F)c(C(F)(F)F)c2)ncn1 -US06852726B2,5,CSCc1cccc(Cl)c1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CSCc1cccc(Cl)c1NC(=O)C(F)(F)F -US20110282075A1,2,CC(=O)OC[C@@H](C)C[C@@H](C)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>CC(=O)OC[C@@H](C)C[C@@H](C)COS(=O)(=O)c1ccc(C)cc1 -US20140275049A1,9,COC(=O)c1ccc(-c2cc(N)n(-c3ccc(C(=O)N4CCN(C)CC4)cc3)n2)cc1.ICI>>COC(=O)c1ccc(-c2cc(I)n(-c3ccc(C(=O)N4CCN(C)CC4)cc3)n2)cc1 -US20110082120A1,6,COC(=O)c1cc(NC(=O)CSSCCNC(=O)OC(C)(C)C)ccc1O>>COC(=O)c1cc(NC(=O)CSSCCN)ccc1O -US06956036B1,1,CC(Cn1ncc2ccc(O)cc21)NC(=O)OCc1ccccc1.CI>>COc1ccc2cnn(CC(C)NC(=O)OCc3ccccc3)c2c1 -US20070027179A1,1,Cc1cc([N+](=O)[O-])cnc1Cl.NCC1CCCCC1>>Cc1cc([N+](=O)[O-])cnc1NCC1CCCCC1 -US20120178755A1,1,CCOC(=O)c1cccc(Oc2ccccc2)c1CBr.COC(=O)CNS(=O)(=O)c1ccc(C)cc1>>CCOC(=O)c1cccc(Oc2ccccc2)c1CN(CC(=O)OC)S(=O)(=O)c1ccc(C)cc1 -US06013654,1,C1CNCCN1.N#Cc1ccc(F)cc1F>>N#Cc1ccc(F)cc1N1CCNCC1 -US20130012523A1,1,CC(C)(N)c1ccccc1OCc1ccccc1.COC(=O)c1ccc(C)c(-n2cc(Br)nc(Br)c2=O)c1>>COC(=O)c1ccc(C)c(-n2cc(Br)nc(NC(C)(C)c3ccccc3OCc3ccccc3)c2=O)c1 -US08877780B2,2,NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O.O=C=Nc1cc(Cl)cc(Cl)c1>>O=C1CCC(N2Cc3cc(CNC(=O)Nc4cc(Cl)cc(Cl)c4)ccc3C2=O)C(=O)N1 -US20130018075A1,2,C=COCCON.COC(=O)c1cc(C)c(=O)n(C)c1Nc1ccc(Br)cc1F>>C=COCCONC(=O)c1cc(C)c(=O)n(C)c1Nc1ccc(Br)cc1F -US20050192253A1,9,Cc1cc(N)ncc1Br.N#C[Cu]>>Cc1cc(N)ncc1C#N -US05925662,2,CCOC(=O)Cl.Nc1ccc2c(c1)CCC(CC(OCc1ccccc1)C(F)(F)F)O2>>CCOC(=O)Nc1ccc2c(c1)CCC(CC(OCc1ccccc1)C(F)(F)F)O2 -US06340759B1,3,C#Cc1ccc(OC)cc1.N#Cc1ncccc1Br>>COc1ccc(C#Cc2cccnc2C#N)cc1 -US08071592B2,7,C=Cc1c(F)cnc2ccc(OC)nc12>>CCc1c(F)cnc2ccc(OC)nc12 -US06977267B2,9,CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)[C@]12CN(CC(=O)O)C[C@H]2c1ccc(C#N)cc1.N>>CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)[C@]12CN(CC(N)=O)C[C@H]2c1ccc(C#N)cc1 -US20110288090A1,7,CC(C)(C)OC(=O)NCc1ccc(-c2nc3ccnc(C=O)c3cc2-c2ccccc2)cc1>>CC(C)(C)OC(=O)NCc1ccc(-c2nc3ccnc(CO)c3cc2-c2ccccc2)cc1 -US04837217,1,CC(C)(C)n1ncc(O)c(Cl)c1=O.CCOC(C)COc1ccc(CBr)cc1>>CCOC(C)COc1ccc(COc2cnn(C(C)(C)C)c(=O)c2Cl)cc1 -US05597831,1,NCCO.O=C1c2ccccc2-c2c1c1ccccc1c(=O)n2CCCl>>O=C1c2ccccc2-c2c1c1ccccc1c(=O)n2CCNCCO -US08431660B2,4,N#Cc1ccccc1O.[N-]=[N+]=[N-]>>Oc1ccccc1-c1nnn[nH]1 -US20130315874A1,2,CCCCCCCCC=CCCCCCCCC(=O)Cl.[N-]=[N+]=NCCN>>CCCCCCCCC=CCCCCCCCC(=O)NCCN=[N+]=[N-] -US05824682,9,CCOC(=O)C1CCc2ccc3ccccc3c2O1.N>>NC(=O)C1CCc2ccc3ccccc3c2O1 -US04436748,6,CCOC(=O)COc1cc2cc(C)sc2c(Cl)c1Cl>>Cc1cc2cc(OCC(=O)O)c(Cl)c(Cl)c2s1 -US08895547B2,6,CC1(C)OC(N[C@@H](CCO[Si](C)(C)C(C)(C)C)c2ccccc2)=NS(=O)(=O)C1c1cccc(Br)c1>>CC1(C)OC(N[C@@H](CCO)c2ccccc2)=NS(=O)(=O)C1c1cccc(Br)c1 -US20100094000A1,3,CC1(C)OB(c2ccc3c(c2)NC(=O)CO3)OC1(C)C.Cc1nn(CC(C)(F)CO)c(-c2ccc(F)cc2)c1Br>>Cc1nn(CC(C)(F)CO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 -US20110152315A1,3,C#Cc1ccc(CCC(=O)OC)cc1.Cc1ccc(I)cc1>>COC(=O)CCc1ccc(C#Cc2ccc(C)cc2)cc1 -US05439925,2,C=CCOC(=O)c1ccc(N)cc1.CC1(C)CCC(C)(C)c2cc(C(F)C(=O)O)ccc21>>C=CCOC(=O)c1ccc(NC(=O)C(F)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 -US08329729B2,1,O=C(CBr)Nc1ccc(C(F)(F)F)nn1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3ccccc3)CCCCCC1)C2)Nc1ccc(C(F)(F)F)nn1 -US20080193413A1,6,CC[C@H](C)CCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NC(=O)OC(C)(C)C)ccc3N2)=C(O)c2ccccc21>>CC[C@H](C)CCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(N)ccc3N2)=C(O)c2ccccc21 -US20090075996A1,2,CS(=O)(=O)Cl.Nc1ccc2c(c1)CCC2=O>>CS(=O)(=O)Nc1ccc2c(c1)CCC2=O -US20090169558A1,1,ClCCN1CCOCC1.Oc1ccc(/C=C/I)cc1>>I/C=C/c1ccc(OCCN2CCOCC2)cc1 -US20110046113A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.C[SiH](C)OCc1c(C(C)(C)C)ccc2cc(C=O)ccc12>>COC(=O)C=Cc1ccc2c(CO[SiH](C)C)c(C(C)(C)C)ccc2c1 -US07705028B2,6,COC(=O)c1cccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3Cl)ccc12>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3c(C(=O)O)cccc3c2)c(Cl)c1 -US06207669B1,6,COC(=O)CNCc1ccc(-c2cc3c(Nc4ccc(OCc5ccccc5)cc4)ncnc3cn2)o1>>O=C(O)CNCc1ccc(-c2cc3c(Nc4ccc(OCc5ccccc5)cc4)ncnc3cn2)o1 -US20110003820A1,2,CC1NCCn2c(-c3ccsc3)ccc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2ccc(-c3ccsc3)n2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US07268128B2,1,CCN(C(=O)OCc1ccccc1)C1CCNCC1.CCOc1cc(Br)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1>>CCOc1cc(N2CCC(N(CC)C(=O)OCc3ccccc3)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1 -US06204264B1,2,CNC.O=C(O)c1ccc(Cl)c([N+](=O)[O-])c1>>CN(C)C(=O)c1ccc(Cl)c([N+](=O)[O-])c1 -US04205128,6,CSCCC(NC(C)=O)C(=O)O>>CSCC[C@H](N)C(=O)O -US08293911B2,1,COc1cc(Br)cc(OC)c1NC(=O)CC(C)(C)C.c1ccc2c(c1)CCNC2>>COc1cc(N2CCc3ccccc3C2)cc(OC)c1NC(=O)CC(C)(C)C -US05576333,2,CC(=O)OC(C)=O.CN(CC(CCN1CCC(NC2CCCCC2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1>>CC(=O)N(C1CCCCC1)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 -US06211199B1,1,CCOC(=O)N1CCC(Nc2nc3ccccc3[nH]2)CC1.CCOC(=O)c1ccc(CCl)o1>>CCOC(=O)c1ccc(Cn2c(NC3CCN(C(=O)OCC)CC3)nc3ccccc32)o1 -US04123529,7,O=C(c1ccc(-c2ccccc2)o1)N1CCN(c2cccc(C(F)(F)F)c2)CC1>>FC(F)(F)c1cccc(N2CCN(Cc3ccc(-c4ccccc4)o3)CC2)c1 -US08524691B2,6,C=CCP(=O)(CC=C)C(CCC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)P(=O)(CC=C)CC=C>>C=CCP(=O)(CC=C)C(CCC(=O)NCCCC[C@H](N)C(=O)O)P(=O)(CC=C)CC=C -US08518972B2,1,Cc1cccc(C2CCNCC2)c1.O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1>>Cc1cccc(C2CCN(Cc3ccc(COc4cccc5c4CN(C4CCC(=O)NC4=O)C5=O)cc3)CC2)c1 -US08546392B2,3,C=CC(=O)O.COc1cc(Br)cc(Br)c1>>COc1cc(Br)cc(/C=C/C(=O)O)c1 -US20100125087A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc(C2(c3cccc(O)c3)N=C(N)c3ncccc32)cc(C)n1>>Cc1cc(C2(c3cccc(O)c3)N=C(NC(=O)OC(C)(C)C)c3ncccc32)cc(C)n1 -US08227485B2,1,CC(C)CN(CC(C)C)C(=O)C(C)(C)c1ccc([N+](=O)[O-])c(Cl)c1.NCCCN1CCCCC1>>CC(C)CN(CC(C)C)C(=O)C(C)(C)c1ccc([N+](=O)[O-])c(NCCCN2CCCCC2)c1 -US05684041,7,CC(C)(C)c1cc([N+](=O)[O-])cc2c1OCC2(C)C>>CC(C)(C)c1cc(N)cc2c1OCC2(C)C -US08236825B2,9,O=C(CCCCl)c1ccccc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCCC(=O)c1ccccc1 -US20020160993A1,7,O=C(CCl)c1ccccc1>>OC(CCl)c1ccccc1 -US20040110767A1,6,Cc1cc(C)c(S(=O)(=O)N(Cc2ccc(OC3CCCCO3)cc2Cl)c2ccc(I)cc2)c(C)c1>>Cc1cc(C)c(S(=O)(=O)N(Cc2ccc(O)cc2Cl)c2ccc(I)cc2)c(C)c1 -US04066772,1,O=c1[nH]c2ccc(Cl)cc2n1CCCCl.OC1(c2ccc(Cl)cc2)CCNCC1>>O=c1[nH]c2ccc(Cl)cc2n1CCCN1CCC(O)(c2ccc(Cl)cc2)CC1 -US05114961,1,CCCOc1c(OCCBr)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)O.Sc1ncc[nH]1>>CCCOc1c(OCCSc2ncc[nH]2)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)O -US20050282880A1,6,COC(=O)c1ccc2[nH]nc(-c3ccccc3F)c2c1>>O=C(O)c1ccc2[nH]nc(-c3ccccc3F)c2c1 -US20060194782A1,2,CCc1cccc(C)c1CNc1nc(C(=O)O)cc2c1nc(C)n2C.CNC>>CCc1cccc(C)c1CNc1nc(C(=O)N(C)C)cc2c1nc(C)n2C -US20150258074A1,3,C#C[Mg+].COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(C=O)c12>>C#CC(O)c1nc(Cl)cc2c1c(OC)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20150203534A1,6,CC(C)(C)OC(=O)N[C@@H](COC(F)F)C(=O)OCc1ccccc1>>N[C@@H](COC(F)F)C(=O)OCc1ccccc1 -US05780501,1,BrCC1=Cc2ccccc2Oc2ccccc21.C=CCN>>C=CCNCC1=Cc2ccccc2Oc2ccccc21 -US05780501,1,BrCC1=Cc2ccccc2Oc2ccccc21.C=CCN>>C=CCNCC1=Cc2ccccc2Oc2ccccc21 -US04230621,6,COc1ccc(CC(CC(=O)O)CC(=O)O)cc1>>O=C(O)CC(CC(=O)O)Cc1ccc(O)cc1 -US05648368,9,CC(C)(C)OC(=O)N1CCC(CCN=[N+]=[N-])CC1>>CC(C)(C)OC(=O)N1CCC(CCN)CC1 -US20140073620A1,1,CC(=O)c1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1.[NH4+]>>CC(N)c1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 -US20110178054A1,6,COC(=O)c1ccc(OCCCC2CCN(c3noc(C(C)(C)F)n3)CC2)cc1C>>Cc1cc(OCCCC2CCN(c3noc(C(C)(C)F)n3)CC2)ccc1C(=O)O -US20150203486A1,7,CCOC(=O)C1CC=C(c2ncc(-c3cn4c(Cc5ccccc5OC(F)F)c(C)nc4cc3F)cn2)CC1>>CCOC(=O)C1CCC(c2ncc(-c3cn4c(Cc5ccccc5OC(F)F)c(C)nc4cc3F)cn2)CC1 -US20150011551A1,2,COc1ccc(-c2cncc(N)c2)cc1.O=S(=O)(Cl)c1cc(Cl)ccc1OC(F)(F)F>>COc1ccc(-c2cncc(NS(=O)(=O)c3cc(Cl)ccc3OC(F)(F)F)c2)cc1 -US06995157B2,1,O=C(CBr)c1ccc(Cl)cc1.O=C1CSC(=O)N1>>O=C(CN1C(=O)CSC1=O)c1ccc(Cl)cc1 -US20010031786A1,6,CCOC(=O)C(Cc1ccc(OCCN(C)C2c3ccccc3CCc3ccccc32)cc1)OCC>>CCOC(Cc1ccc(OCCN(C)C2c3ccccc3CCc3ccccc32)cc1)C(=O)O -US06359145B1,9,COC(=O)c1cn([C@H](CCc2cccc3ccccc23)[C@H](C)OCc2ccccc2)cn1.[NH4+]>>C[C@H](OCc1ccccc1)[C@@H](CCc1cccc2ccccc12)n1cnc(C(N)=O)c1 -US07332499B2,2,C[C@@H]([NH3+])c1ccc(Br)cc1F.O=C(NC1(C(=O)O)CC1)C(F)(F)F>>C[C@@H](NC(=O)C1(NC(=O)C(F)(F)F)CC1)c1ccc(Br)cc1F -US08501750B2,1,CCc1cc2c(=O)[nH]c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3F)c2s1.COc1ccc(C(=O)CBr)cc1>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3F)c2s1 -US08669255B2,1,Clc1ccc(O[C@@H]2CCN3CCNC[C@H]23)nc1.Fc1cccc(C(F)(F)F)n1>>FC(F)(F)c1cccc(N2CCN3CC[C@@H](Oc4ccc(Cl)cn4)[C@H]3C2)n1 -US05478842,1,CN1C(=O)Cc2cc(S)ccc21.C[C@H]1C[C@@](O)(c2cnc(Cl)s2)CCO1>>C[C@H]1C[C@@](O)(c2cnc(Sc3ccc4c(c3)CC(=O)N4C)s2)CCO1 -US07642276B2,2,CCCN.COC(=O)Cn1ncc2cc(-c3cc(C(=O)NC4CC4)cc(F)c3C)ccc21>>CCCNC(=O)Cn1ncc2cc(-c3cc(C(=O)NC4CC4)cc(F)c3C)ccc21 -US04863926,3,C/C=C(/C=O)CC.CCOP(=O)(CC#N)OCC>>C/C=C(/C=C/C#N)CC -US20080076745A1,6,CC(C)(C)OC(=O)NCC[C@H](NC(=O)OCc1ccccc1)C(=O)NCC(O)CNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCC[C@H](N)C(=O)NCC(O)CNC(=O)OC(C)(C)C -US06498165B1,3,Brc1cncnc1.CCCC[Sn](CCCC)(CCCC)c1ccc2c(c1)ncn2-c1ccnc(N[C@@H](C)c2ccccc2)n1>>C[C@H](Nc1nccc(-n2cnc3cc(-c4cncnc4)ccc32)n1)c1ccccc1 -US06355680B1,1,COc1ccc(Cl)c(N)c1.O=C(O)Cc1ccccc1Br>>COc1ccc(Cl)c(Nc2ccccc2CC(=O)O)c1 -US04021479,7,O=C(O)CCC(=O)c1ccc(-c2cccc(Cl)c2)cc1>>O=C(O)CCC(O)c1ccc(-c2cccc(Cl)c2)cc1 -US20040242455A1,5,NCCc1ccc(Br)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCc1ccc(Br)cc1)C(F)(F)F -US05773612,2,CCN(CC)C(=O)Nc1ccc(S(=O)(=O)Cl)cc1.NC1(c2ccccc2)C(=O)Nc2ccc(Cl)c(Cl)c21>>CCN(CC)C(=O)Nc1ccc(S(=O)(=O)N2C(=O)C(N)(c3ccccc3)c3c2ccc(Cl)c3Cl)cc1 -US20130040930A1,1,CC(C)C1NC(=O)NC1=O.COc1ccc(CCl)cc1>>COc1ccc(CN2C(=O)NC(C(C)C)C2=O)cc1 -US20120232033A1,1,CC(C)(C)OC(=O)NC(C(=O)c1ccc(O)cc1)c1ccc(Cl)c(Cl)c1.OCC1CC1>>CC(C)(C)OC(=O)NC(C(=O)c1ccc(OCC2CC2)cc1)c1ccc(Cl)c(Cl)c1 -US20100305133A1,6,CCOC(=O)CNC(=O)c1c(O)c(-c2cccs2)cc2nc(-c3cccs3)cnc12>>O=C(O)CNC(=O)c1c(O)c(-c2cccs2)cc2nc(-c3cccs3)cnc12 -US20090281084A1,10,CCOC(=O)c1oc(-c2ccc(C(F)(F)F)cc2)nc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1oc(-c2ccc(C(F)(F)F)cc2)nc1CBr -US20140323468A1,3,CC(=O)c1cncc(Br)c1.CC(C)(C)OC(=O)N1CCCc2cc(Br)cnc21>>CC(=O)c1cncc(-c2cnc3c(c2)CCCN3C(=O)OC(C)(C)C)c1 -US06432968B1,1,CC(C)(O)CCCCCl.CCCCn1cnc2c1c(=O)[nH]c(=O)n2C>>CCCCn1cnc2c1c(=O)n(CCCCC(C)(C)O)c(=O)n2C -US20140288046A1,1,CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn[nH]c2n1.FC(F)(F)c1ccccc1CBr>>CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nnn(Cc3ccccc3C(F)(F)F)c2n1 -US07635715B2,9,Clc1cccc(I)c1CBr.[C-]#N>>N#CCc1c(Cl)cccc1I -US20110086843A1,2,CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)Cl)s2)s1.CC1(C)OCC(CN)O1>>CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)NCC3COC(C)(C)O3)s2)s1 -US08163923B2,1,CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12.O=CC1CC1>>CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(NCC6CC6)CC5)c(OC)cc34)ccc12 -US20100113782A1,1,CC(C)(C)OC(=O)c1ccc(Br)cc1.CC(C)(C)c1cccc(NC(=O)c2ccc(C3CCNCC3)cc2)c1>>CC(C)(C)OC(=O)c1ccc(N2CCC(c3ccc(C(=O)Nc4cccc(C(C)(C)C)c4)cc3)CC2)cc1 -US20150072969A1,1,CCOC(=O)CC1(c2ccc(O)cc2)COC1.Cc1ccc(CBr)cc1C(F)(F)F>>CCOC(=O)CC1(c2ccc(OCc3ccc(C)c(C(F)(F)F)c3)cc2)COC1 -US05472978,6,Cc1cc(C)cc(COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)c1>>Cc1cc(C)cc(COC(=O)C(N)Cc2c[nH]c3ccccc23)c1 -US08232289B2,1,Cc1n[nH]cc1C=O.N#Cc1cccnc1F>>Cc1nn(-c2ncccc2C#N)cc1C=O -US08586617B2,9,CCN(Cc1cnc[nH]1)c1cc(Cl)nc(Cc2ccccc2)n1>>CCN(Cc1cnc[nH]1)c1ccnc(Cc2ccccc2)n1 -US07576135B2,2,COC(=O)C(=O)Cl.Nc1ncc(Cl)cn1>>COC(=O)C(=O)Nc1ncc(Cl)cn1 -US20100093726A1,7,O=C(c1ccc(Cl)cc1)c1ccc(Cn2ccnc2)cc1>>OC(c1ccc(Cl)cc1)c1ccc(Cn2ccnc2)cc1 -US20060205715A1,1,NC(=O)c1ccc(Oc2ccc3c(c2)CCCC3=O)cc1.NCc1ccccc1>>NC(=O)c1ccc(Oc2ccc3c(c2)CCCC3NCc2ccccc2)cc1 -US20080280889A1,5,N#Cc1ccc(C=O)cc1.OCCO>>N#Cc1ccc(C2OCCO2)cc1 -US20080194647A1,6,C[Si](C)(C)C#Cc1cccc(C(F)(F)F)c1>>C#Cc1cccc(C(F)(F)F)c1 -US20080108598A1,7,CN(C)c1ccc(C(=O)N2C3CCC2CC(=O)C3)cc1>>CN(C)c1ccc(C(=O)N2C3CCC2CC(O)C3)cc1 -US08133849B2,2,COC(=O)c1nccnc1N.O=S(=O)(Cl)Cc1cc(C(F)(F)F)ccc1Cl>>COC(=O)c1nccnc1NS(=O)(=O)Cc1cc(C(F)(F)F)ccc1Cl -US20080045530A1,2,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.COC(=O)[C@H]1CNC[C@@H]1c1ccccc1>>COC(=O)[C@H]1CN(C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)C[C@@H]1c1ccccc1 -US07214824B2,2,CC(C)(C)c1ccc(OCC(=O)O)cc1Cl.C[C@@H](N)c1ccc(NS(C)(=O)=O)c(F)c1>>C[C@@H](NC(=O)COc1ccc(C(C)(C)C)c(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 -US20110071147A1,2,CC(O)CN.CCOC(=O)c1cnc(N)c2c(COc3ccc(Br)cc3)csc12>>CC(O)CNC(=O)c1cnc(N)c2c(COc3ccc(Br)cc3)csc12 -US08921389B2,2,CN.COC(=O)c1ncc2c(c1O)CCN(Cc1ccc(OC)cc1OC)C2=O>>CNC(=O)c1ncc2c(c1O)CCN(Cc1ccc(OC)cc1OC)C2=O -US20120122842A1,2,CC(=O)Cl.CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(N)cc3C2)cc1>>CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(NC(C)=O)cc3C2)cc1 -US07932281B2,1,CCCN(CCC)CCCCNC(=O)c1ccc(CN)cc1.Cn1ccnc1C=O>>CCCN(CCC)CCCCNC(=O)c1ccc(CNCc2nccn2C)cc1 -US07732466B2,2,Cc1cc(NC(=O)[C@H](N)Cc2c[nH]cn2)ccc1C(=O)N1CCCC1.O=C(O)c1ccc(Br)s1>>Cc1cc(NC(=O)[C@@H](Cc2c[nH]cn2)NC(=O)c2ccc(Br)s2)ccc1C(=O)N1CCCC1 -US20090192325A1,2,C=C1CNC(OC(=O)O[C@H](C)OC(=O)C(C)C)O1.NCC1(CC(=O)O)CCCCC1>>CC(C)C(=O)O[C@@H](C)OC(=O)NCC1(CC(=O)O)CCCCC1 -US03969409,3,C1CCNCC1.C=O.CC1(C)CC(=O)C=C(Nc2ccccc2Cl)C1>>CC1(C)CC(=O)C(CN2CCCCC2)=C(Nc2ccccc2Cl)C1 -US20050032838A1,1,CSc1cc(O)ccc1Cl.O=C(N[C@@H]1CC[C@@H](O)CC1)c1cc(F)cnc1Cl>>CSc1cc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@@H](O)CC2)ccc1Cl -US20060281789A1,2,NCCN1CCOCC1.O=C(O)c1ccc(/C=C/c2n[nH]c3ccccc23)cc1>>O=C(NCCN1CCOCC1)c1ccc(/C=C/c2n[nH]c3ccccc23)cc1 -US20060178408A1,2,COC(=O)c1cccc(N)c1.CS(=O)(=O)Cl>>COC(=O)c1cccc(NS(C)(=O)=O)c1 -US20150018341A1,2,CNOC.O=C(O)c1ccc(O)cn1>>CON(C)C(=O)c1ccc(O)cn1 -US20090030015A1,6,COC(=O)c1cccc(-c2ccc(OC)cc2OC)c1>>COc1ccc(-c2cccc(C(=O)O)c2)c(OC)c1 -US20130109665A1,2,CC(C)(O)[C@@H](N)CC1CC1.O=C(O)c1cnc(C2CC2)c(OCC2CC2)n1>>CC(C)(O)[C@H](CC1CC1)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 -US20040247934A1,6,COc1cccc(-c2ccccn2)c1>>Oc1cccc(-c2ccccn2)c1 -US04738709,2,COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1O.NO>>O=C(NO)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1O -US20050107400A1,3,C#C[Mg+].O=Cc1c(-c2ccc(F)cc2)nn2cc(C(F)(F)F)ccc12>>C#CC(O)c1c(-c2ccc(F)cc2)nn2cc(C(F)(F)F)ccc12 -US20120209001A1,1,CC(C)(C)n1nc(CCC=O)cc1-c1ccc(F)cc1.Cc1cccc(N2CCNCC2C)c1>>Cc1cccc(N2CCN(CCCc3cc(-c4ccc(F)cc4)n(C(C)(C)C)n3)CC2C)c1 -US05723450,1,Clc1ccnc(Cl)c1Br.N[C@H]1CC[C@@H](c2ccccc2)CC1>>Clc1nccc(N[C@H]2CC[C@@H](c3ccccc3)CC2)c1Br -US05763604,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1CN(Cc2ccccc2)CCO1>>CC(C)(C)OC(=O)NCC1CN(Cc2ccccc2)CCO1 -US20090137580A1,2,Cn1ccc2ncnc(Oc3ccc(N)cc3)c21.O=C=Nc1cccc(F)c1>>Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(F)c4)cc3)c21 -US06194396B1,9,COc1cccc2cc(CO)oc12>>COc1cccc2cc(C)oc12 -US20100056490A1,1,CC(C)(C)OC(=O)N[C@H]1CSC[C@@H](Cc2cc(F)c([N+](=O)[O-])c(F)c2)[C@@H]1O.COC[C@@H](O)C(F)(F)F>>COC[C@@H](Oc1cc(C[C@@H]2CSC[C@H](NC(=O)OC(C)(C)C)[C@H]2O)cc(F)c1[N+](=O)[O-])C(F)(F)F -US20110263571A1,1,CC1(C)CNC(=O)O1.Cc1cc(C#N)cnc1N1CCN(C(=O)c2ccc(Br)nc2)CC1>>Cc1cc(C#N)cnc1N1CCN(C(=O)c2ccc(N3CC(C)(C)OC3=O)nc2)CC1 -US04772703,6,COc1cccc(CCNS(=O)(=O)C(F)(F)F)c1>>O=S(=O)(NCCc1cccc(O)c1)C(F)(F)F -US08513252B2,1,COc1ccc(Cn2cc(-c3nc(Br)sc3C#N)cn2)cc1.Oc1ccccn1>>COc1ccc(Cn2cc(-c3nc(Oc4ccccn4)sc3C#N)cn2)cc1 -US08258134B2,1,O=c1c(Cl)c(Cl)cnn1C1CCCCO1.Oc1ccccc1>>O=c1c(Cl)c(Oc2ccccc2)cnn1C1CCCCO1 -US05646171,6,CCCc1nc(C(C)O)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCc1nc(C(C)O)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US20110034434A1,1,ClCCOCCl.O=C(OCc1ccccc1)c1cc2occc2[nH]1>>O=C(OCc1ccccc1)c1cc2occc2n1COCCCl -US20040014968A1,2,CN.O=C(O)c1ccc(NC(=O)C(CC2CCCC2)c2ccc(Cl)c(Cl)c2)nc1>>CNC(=O)c1ccc(NC(=O)C(CC2CCCC2)c2ccc(Cl)c(Cl)c2)nc1 -US20100143505A1,6,COc1cc2c(cc1OC)C(=O)C(CC1CCN(C(=O)OC(C)(C)C)CC1)C2>>COc1cc2c(cc1OC)C(=O)C(CC1CCNCC1)C2 -US08030354B2,7,COC(=O)c1ccc(-c2cc(OC)ccc2F)c(C2=CC(C)(C)CC(C)(C)C2)c1>>COC(=O)c1ccc(-c2cc(OC)ccc2F)c(C2CC(C)(C)CC(C)(C)C2)c1 -US20120232096A1,6,COc1c(C)cc(C)c2c1OC(C)(C)C2=O>>Cc1cc(C)c2c(c1O)OC(C)(C)C2=O -US20080214538A1,2,CC(=O)OC(C)=O.Cc1ccc(NN)cc1>>CC(=O)NNc1ccc(C)cc1 -US20110294781A1,1,C1COCCN1.Clc1cccc(-c2cc3nc(Cl)cc(Cl)n3n2)c1>>Clc1cccc(-c2cc3nc(Cl)cc(N4CCOCC4)n3n2)c1 -US20130296312A1,1,CN1CCNCC1.COc1ccc(Nc2nc3c(Br)cccn3n2)cc1>>COc1ccc(Nc2nc3c(N4CCN(C)CC4)cccn3n2)cc1 -US20050043353A1,2,NC12CC3CC(CC(C3)C1)C2.O=C(Cl)CCl>>O=C(CCl)NC12CC3CC(CC(C3)C1)C2 -US04897109,2,COc1ccc(CNC(C)C)cc1OC.O=C(O)C(Cl)Cl>>COc1ccc(CN(C(=O)C(Cl)Cl)C(C)C)cc1OC -US08618286B2,6,CN(CCN1CCSc2ccc(NC(=N)c3cccs3)cc21)C(=O)OC(C)(C)C>>CNCCN1CCSc2ccc(NC(=N)c3cccs3)cc21 -US20150218096A1,6,COC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(C#CCOC4CCCCO4)ccc23)c(F)c1>>COC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(C#CCO)ccc23)c(F)c1 -US20080103123A1,3,CN(Cc1ccc(Br)cn1)C1CCN(C(=O)OC(C)(C)C)CC1.N#Cc1ccc(B(O)O)cc1>>CN(Cc1ccc(-c2ccc(C#N)cc2)cn1)C1CCN(C(=O)OC(C)(C)C)CC1 -US20080045493A1,7,O=[N+]([O-])c1ccc(C2CCN(Cc3ccccc3)C2)cc1F>>Nc1ccc(C2CCN(Cc3ccccc3)C2)cc1F -US20150210682A1,1,COCCCOc1cc(CC(=O)C(C)(C)C)ccc1Cl.[NH4+]>>COCCCOc1cc(CC(N)C(C)(C)C)ccc1Cl -US20120065184A1,7,O=C(C=Cc1cccc(F)c1)c1cnc2ccc(N3CCC[C@@H]3c3cccc(F)c3)nn12>>O=C(CCc1cccc(F)c1)c1cnc2ccc(N3CCC[C@@H]3c3cccc(F)c3)nn12 -US20150025065A1,1,CS(C)(=O)=Nc1ccc2c(c1)CNC2.C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)nc2cc(Cl)c(-c3ccc(Br)cc3)nc21>>C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)nc2cc(Cl)c(-c3ccc(N4Cc5ccc(N=S(C)(C)=O)cc5C4)cc3)nc21 -US06916804B2,1,CC(=O)NCCN.Nc1cc(Cl)nc(-c2ccccc2)n1>>CC(=O)NCCNc1cc(N)nc(-c2ccccc2)n1 -US07015218B1,2,Cc1c(C(=O)O)cnn1-c1ccc(Cl)cc1.NC(=O)c1cc(N)ccc1N1CCC(N2CCOCC2)CC1>>Cc1c(C(=O)Nc2ccc(N3CCC(N4CCOCC4)CC3)c(C(N)=O)c2)cnn1-c1ccc(Cl)cc1 -US20090099199A1,7,O=[N+]([O-])c1ccc(N2CCC(C(c3ccccn3)c3ccccn3)CC2)c(F)c1>>Nc1ccc(N2CCC(C(c3ccccn3)c3ccccn3)CC2)c(F)c1 -US08338437B2,6,COc1ccccc1CNC(=O)c1cc(C(F)(F)F)nn1-c1cccc(CNC(=O)OC(C)(C)C)c1>>COc1ccccc1CNC(=O)c1cc(C(F)(F)F)nn1-c1cccc(CN)c1 -US20100210641A1,1,ClCCCN1CCCCC1.Oc1cccc(-c2ccn3c(-c4ccnc(-c5ccc(F)cc5)c4)cnc3c2)c1>>Fc1ccc(-c2cc(-c3cnc4cc(-c5cccc(OCCCN6CCCCC6)c5)ccn34)ccn2)cc1 -US06951879B2,1,C1CNC1.CS(=O)(=O)OCCC#Cc1ccc2c(-c3ccc(Br)cc3)nsc2c1>>Brc1ccc(-c2nsc3cc(C#CCCN4CCC4)ccc23)cc1 -US20130072519A1,2,CC(C)Oc1ccc(-c2ccccc2C(=O)O)cc1.CCOC(=O)C(C(=O)OCC)c1ccc(N)c(C(=O)N(C)C)c1>>CCOC(=O)C(C(=O)OCC)c1ccc(NC(=O)c2ccccc2-c2ccc(OC(C)C)cc2)c(C(=O)N(C)C)c1 -US07875728B2,1,C1COCCN1.CCOC(=O)CCCCBr>>CCOC(=O)CCCCN1CCOCC1 -US20150018363A1,1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1cc(Br)c(Cl)s1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cc(Br)c(Cl)s4)cc3=O)cc21 -US20110275797A1,1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(Br)ccc1OCc1ccccc1.CNCCN1CCOCC1>>CN(CCN1CCOCC1)c1ccc(OCc2ccccc2)c(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)OC(C)(C)C)c1 -US08067472B2,2,Nc1ccccc1.O=C(O)CCCCCCC(=O)O>>O=C(O)CCCCCCC(=O)Nc1ccccc1 -US08598226B2,5,COCCl.Cc1cc(O)cc(C)c1Br>>COCOc1cc(C)c(Br)c(C)c1 -US20120238548A1,1,CC1(C)OCC(=O)N[C@](C)(c2cc(Br)ccc2F)C1(F)F.Nc1ccc(Cl)nc1>>CC1(C)OCC(=O)N[C@](C)(c2cc(Nc3ccc(Cl)nc3)ccc2F)C1(F)F -US20150183784A1,7,CCc1cc2cc(S(C)(=O)=O)cc(-c3cn(C)c(=O)c4ccccc34)c2o1>>CCC1Cc2cc(S(C)(=O)=O)cc(-c3cn(C)c(=O)c4ccccc34)c2O1 -US07629340B2,3,Brc1ccc2ncsc2c1.CC1(C)OB(c2cccc(NC(=O)[C@@H]3CCCN3C(=O)OCc3ccccc3)c2)OC1(C)C>>O=C(Nc1cccc(-c2ccc3ncsc3c2)c1)[C@@H]1CCCN1C(=O)OCc1ccccc1 -US08304419B2,1,CCOC(=O)c1[nH]cnc1N.CN(C)C=O>>CCOC(=O)c1[nH]cnc1/N=C/N(C)C -US07897601B2,3,C#Cc1ccc(Cl)cc1.Clc1ccc(I)c(Cl)c1>>Clc1ccc(C#Cc2ccc(Cl)cc2Cl)cc1 -US20060052392A1,7,Cc1cc2c(cc1C)C(=O)OC2=O>>Cc1cc2c(cc1C)C(O)OC2=O -US04758568,1,CC(=O)N(C)C.COc1cc(N)c(C#N)cc1OC>>COc1cc(C#N)c(N=C(C)N(C)C)cc1OC -US20150232472A1,7,Cn1nc(N2CCCC2)nc1C=O>>Cn1nc(N2CCCC2)nc1CO -US20040043995A1,6,CCc1ccc2c(c1)cc(C(=O)OCc1ccccc1)n2CC(=O)OC>>CCc1ccc2c(c1)cc(C(=O)O)n2CC(=O)OC -US20020193389A1,1,N#Cc1ccccc1F.NC1CCC1>>N#Cc1ccccc1NC1CCC1 -US20100249054A9,1,CC(=O)O.O=C(O)c1cc(O)cc(OCc2ccccc2)c1>>CC(=O)Oc1cc(OCc2ccccc2)cc(C(=O)O)c1 -US20050250753A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1ccccc1Br>>CC(C)(C)OC(=O)NCc1ccccc1Br -US20120101064A1,1,CN(C)CCO.Nc1cc(F)ccc1[N+](=O)[O-]>>CN(C)CCOc1ccc([N+](=O)[O-])c(N)c1 -US20130217666A1,3,C#CC(C)(C)O.NC(=O)c1nc2n(c1CN1CCC(=O)C1)CCOc1ccc(Br)cc1-2>>CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(CN3CCC(=O)C3)n1CCO2 -US07279470B2,2,CN(C(=O)Oc1ccc(N)cn1)c1ccccc1.O=S(=O)(Cl)c1ccccc1>>CN(C(=O)Oc1ccc(NS(=O)(=O)c2ccccc2)cn1)c1ccccc1 -US20130253004A1,3,O=Cc1cscc1Br.[Mg+]CCCc1ccccc1>>OC(CCCc1ccccc1)c1cscc1Br -US05292760,7,CNC(Cc1ccc(C(F)(F)F)cc1[N+](=O)[O-])c1sccc1C>>CNC(Cc1ccc(C(F)(F)F)cc1N)c1sccc1C -US20100055094A1,2,CC(C)(C)OC(=O)Nc1c[nH]nc1C(=O)O.Nc1ccc(CN2CCOCC2)cc1N>>CC(C)(C)OC(=O)Nc1c[nH]nc1C(=O)Nc1ccc(CN2CCOCC2)cc1N -US08822471B2,2,CC(C)c1noc(N2CCC(NC3CC3)CC2)n1.Cc1ncnn1-c1ccc(C(=O)O)cc1>>Cc1ncnn1-c1ccc(C(=O)N(C2CC2)C2CCN(c3nc(C(C)C)no3)CC2)cc1 -US20090170921A1,3,COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)ccc(OC)c21.OB(O)c1ccccc1>>COCCn1c(-c2ccc(C(C)C)cc2)nc2c(-c3ccccc3)ccc(OC)c21 -US04263207,6,COC(=O)c1ccc2c(c1)S(=O)c1ccccc1NC2=O>>O=C(O)c1ccc2c(c1)S(=O)c1ccccc1NC2=O -US20110082129A1,7,CSc1ccc(C=O)cc1C#N>>CSc1ccc(CO)cc1C#N -US20140315886A1,3,CNc1nc(-c2cccnc2)nc2cc(F)c(Br)cc12.OB(O)c1cccc(F)c1>>CNc1nc(-c2cccnc2)nc2cc(F)c(-c3cccc(F)c3)cc12 -US20140093453A1,2,CCN(CCN)CCOc1cccnc1F.CCOC(=O)c1ccc2cc(I)ccc2c1>>CCN(CCNC(=O)c1ccc2cc(I)ccc2c1)CCOc1cccnc1F -US06344562B1,2,CCOC(=O)CCCc1csc(N)n1.O=C=NCc1ccccc1>>CCOC(=O)CCCc1csc(NC(=O)NCc2ccccc2)n1 -US07820649B2,7,CCC1NCCCNC1=O>>CCC1CNCCCN1 -US06329370B1,9,COC(=O)c1nnc(Cc2c(Cl)cncc2Cl)c2ccc(OC)cc12.N>>COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(C(N)=O)c2c1 -US20050143452A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1ccc(F)cc1F>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4ccc(F)cc4F)c3O2)cc1 -US07902367B2,1,CC(C)(C)OC(=O)N1CCCC(CO)C1.Cc1nc(-c2ccc(Cl)cc2)sc1CCl>>Cc1nc(-c2ccc(Cl)cc2)sc1COCC1CCCN(C(=O)OC(C)(C)C)C1 -US20140228363A1,1,CCO.COC(=O)c1ccc(F)c(-c2c(F)cc(O)cc2F)n1>>CCOc1cc(F)c(-c2nc(C(=O)OC)ccc2F)c(F)c1 -US05302720,3,CS(=O)(=O)c1ccc(I)cc1.O=[N+]([O-])c1ccccc1Br>>CS(=O)(=O)c1ccc(-c2ccccc2[N+](=O)[O-])cc1 -US08222248B2,2,Cc1ccc(N)cc1C.O=C(O)c1ccc(O)c([N+](=O)[O-])c1>>Cc1ccc(NC(=O)c2ccc(O)c([N+](=O)[O-])c2)cc1C -US20100204224A1,2,O=C=Nc1ccc(Oc2ccccc2)cc1.c1ccc(CN2CC3CNCC3C2)cc1>>O=C(Nc1ccc(Oc2ccccc2)cc1)N1CC2CN(Cc3ccccc3)CC2C1 -US20150274628A1,6,CCCCCCCCCCCCCC1=C(OC)C(=O)C=C(NCCCC(=O)OC(C)(C)C)C1=O>>CCCCCCCCCCCCCC1=C(OC)C(=O)C=C(NCCCC(=O)O)C1=O -US20140128390A1,2,CC1(C)CN(c2ncnc3cc(N4CCC(F)(F)CC4)sc23)CCN1.COc1cccc([C@H](C)N=C=O)c1>>COc1cccc([C@H](C)NC(=O)N2CCN(c3ncnc4cc(N5CCC(F)(F)CC5)sc34)CC2(C)C)c1 -US08394795B2,6,CCN(c1ccc(F)c(C(=O)OC)c1F)S(=O)(=O)NC>>CCN(c1ccc(F)c(C(=O)O)c1F)S(=O)(=O)NC -US20050272778A1,3,C=CC(=O)OC.COC(=O)c1ccc(I)c(Br)c1>>COC(=O)/C=C/c1ccc(C(=O)OC)cc1Br -US06777417B2,6,CC(=O)OCC(=O)N1CCN(CCCc2c(C=O)[nH]c3c2CCCC3)CC1>>O=Cc1[nH]c2c(c1CCCN1CCN(C(=O)CO)CC1)CCCC2 -US20150133425A1,2,CNCCO.COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)O)C3>>COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)N(C)CCO)C3 -US04942237,2,O=C(Cl)Cl.c1ccc2c(c1)NC1CCCc3onc-2c31>>O=C(Cl)N1c2ccccc2-c2noc3c2C1CCC3 -US05234946,7,O=Cc1cccc(C2CCCSC2)c1>>OCc1cccc(C2CCCSC2)c1 -US06706724B2,9,CS(=O)(=O)c1ccc(-c2ccccc2C(O)c2cccc(F)c2)cc1>>CS(=O)(=O)c1ccc(-c2ccccc2Cc2cccc(F)c2)cc1 -US08921546B2,7,CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(CCC(=O)N5CCCCC5)ccc34)cc2)no1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(CCCN5CCCCC5)ccc34)cc2)no1 -US20090062272A1,2,C1CCNCC1.CCOCc1nc2cnc3ccccc3c2n1CCCCS(=O)(=O)Cl>>CCOCc1nc2cnc3ccccc3c2n1CCCCS(=O)(=O)N1CCCCC1 -US08173650B2,3,CN(C)C=O.C[C@@H]1COCCN1c1nc(Cl)nc2c1ncn2C>>C[C@@H]1COCCN1c1nc(Cl)nc2c1nc(C=O)n2C -US20050119246A1,1,Cc1n[nH]c(C)c1Oc1ccc(Cl)cc1.NCCCl>>Cc1nn(CCN)c(C)c1Oc1ccc(Cl)cc1 -US06479486B2,7,O=S(=O)(c1ccccc1)[C@@H]1C[C@]2(c3ccccc3)N(Cc3ccccc3)[C@H]1CC[C@@]2(O)C#CCO>>O=S(=O)(c1ccccc1)[C@@H]1C[C@]2(c3ccccc3)N(Cc3ccccc3)[C@H]1CC[C@@]2(O)/C=C\CO -US20100152177A1,6,CC(=O)n1cc(N2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21>>CC(C)(C)OC(=O)N1CCN(c2c[nH]c3ccccc23)CC1 -US20100022476A1,2,COc1cc(OCCCl)c2c(Nc3cc(CC(=O)O)[nH]n3)ncnc2c1.Nc1ccccc1>>COc1cc(OCCCl)c2c(Nc3cc(CC(=O)Nc4ccccc4)[nH]n3)ncnc2c1 -US04220798,6,COC(=O)CCCCCC[C@H]1C(=O)CC[C@@H]1C=CC(O)CCC=C(C)C>>CC(C)=CCCC(O)C=C[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)O -US20150158865A1,2,N#Cc1ncc(N2CCC[C@@H](N)C2)nc1Cl.O=C(O)c1ccc2nccn2c1>>N#Cc1ncc(N2CCC[C@@H](NC(=O)c3ccc4nccn4c3)C2)nc1Cl -US06235789B1,7,COc1ccc2c(c1)C(=CC#N)CCC2>>COc1ccc2c(c1)C(=CCN)CCC2 -US20110130383A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1ccc2c(c1)CCNCC2>>Cc1ccc(S(=O)(=O)N2CCc3ccc([N+](=O)[O-])cc3CC2)cc1 -US20130040930A1,1,O=C(c1ccc(Cl)cc1)C1CCN(C(=O)c2ccc(Br)nc2)CC1.O=C1CCCN1>>O=C(c1ccc(Cl)cc1)C1CCN(C(=O)c2ccc(N3CCCC3=O)nc2)CC1 -US07390805B2,1,CCOC(=O)c1ccc(-c2cc3c(Cl)ncn(Cc4ccc(OC)cc4)c-3n2)cc1.Cc1cc2c(F)c(O)ccc2[nH]1>>CCOC(=O)c1ccc(-c2cc3c(Oc4ccc5[nH]c(C)cc5c4F)ncn(Cc4ccc(OC)cc4)c-3n2)cc1 -US20150038438A1,3,C=CCCCC(O[Si](C)(C)C(C)(C)C)c1ccc(N(C)C)cc1C=C>>CN(C)c1ccc2c(c1)C=CCCCC2O[Si](C)(C)C(C)(C)C -US20110263571A1,2,COC(=O)c1ccc(Br)cc1N1CCCS1(=O)=O.Cc1cnc(N2CCNCC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3N3CCCS3(=O)=O)CC2)c(C)c1 -US20130059996A1,10,Cc1cc(Br)ccc1I.O=C1CCC(=O)N1Br>>BrCc1cc(Br)ccc1I -US20140323530A1,3,C#CCCOC.CC(C)(C)OC(=O)NCCCc1cccc(Br)c1>>COCCC#Cc1cccc(CCCNC(=O)OC(C)(C)C)c1 -US20140171447A1,3,C#CCCNC(=O)OCc1ccccc1.COC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)c2ccccc12)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(C#CCCNC(=O)OCc2ccccc2)c2ccccc12)NC(=O)OC(C)(C)C -US20100022529A1,1,CCOC(=O)c1c(CBr)n(C)n(-c2ccc(F)cc2)c1=O.c1cn[nH]c1>>CCOC(=O)c1c(Cn2cccn2)n(C)n(-c2ccc(F)cc2)c1=O -US08461348B2,6,CCOC(=O)c1cnn(Cc2nc(-c3cc(C#C[Si](C)(C)C)cc(C(F)(F)F)c3)cs2)c1>>C#Cc1cc(-c2csc(Cn3cc(C(=O)OCC)cn3)n2)cc(C(F)(F)F)c1 -US20100256092A1,7,CC(C)CCC(=O)NCC1OB(O)c2cc([N+](=O)[O-])ccc21>>CC(C)CCC(=O)NCC1OB(O)c2cc(N)ccc21 -US20130040930A1,1,CN1C(=O)CNC1=O.Cc1cnc(N2CCN(C(=O)c3ccc(I)cc3)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CC(=O)N(C)C4=O)cc3)CC2)c(C)c1 -US20020177594A1,1,C1=COCCC1.N#CC(O)CCCCCCOc1ccc(-c2ccccc2)cc1>>N#CC(CCCCCCOc1ccc(-c2ccccc2)cc1)OC1CCCCO1 -US04441913,2,CC(Br)C(=O)Br.OCCOCc1ccccc1>>CC(Br)C(=O)OCCOCc1ccccc1 -US08735385B2,2,C[C@H]1CCCN1C1CC[C@H](c2ccc(N)cc2)C1.Cc1ccccc1C(=O)Cl>>Cc1ccccc1C(=O)Nc1ccc([C@H]2CCC(N3CCC[C@@H]3C)C2)cc1 -US20130289026A1,3,CCNC(=O)c1cc(-c2cc(Br)c(OCc3ccccc3)cc2OCc2ccccc2)on1.OB(O)/C=C/c1ccccc1>>CCNC(=O)c1cc(-c2cc(C=Cc3ccccc3)c(OCc3ccccc3)cc2OCc2ccccc2)on1 -US08877683B2,2,CC(C)(C)C(=O)Cl.O=S1(=O)Cc2cccnc2C(O)=C1c1ccccc1C(F)(F)F>>CC(C)(C)C(=O)OC1=C(c2ccccc2C(F)(F)F)S(=O)(=O)Cc2cccnc21 -US04785090,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(CCO)C(=O)O>>CC(C)(C)OC(=O)NC(CCO)C(=O)O -US20110046378A1,5,COCCl.O=Cc1ccc(OCc2ccccc2)c(O)c1>>COCOc1cc(C=O)ccc1OCc1ccccc1 -US20150080400A1,6,CCOC(=O)CCc1ccc(F)c(NC(=O)c2cc(-c3cccc(F)c3)cc3ccccc23)c1>>O=C(O)CCc1ccc(F)c(NC(=O)c2cc(-c3cccc(F)c3)cc3ccccc23)c1 -US05093328,1,C=O.CN(C)C(=O)[C@@H]1C[C@@H](O)CN1>>CN(C)C(=O)[C@@H]1C[C@@H](O)CN1C -US05186717,2,Cc1cc(N)c(N)c([N+](=O)[O-])c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2cc(C)cc([N+](=O)[O-])c2N)cc1 -US20090048259A1,1,C[C@H]1CN[C@@H](C)CN1.Clc1nnc(Cl)c2ccccc12>>C[C@H]1CN(c2nnc(Cl)c3ccccc23)[C@@H](C)CN1 -US08518972B2,1,O=C1CCC(N2Cc3c(OCc4cccc(CBr)c4)cccc3C2=O)C(=O)N1.O=S(=O)(N1CCNCC1)C(F)(F)F>>O=C1CCC(N2Cc3c(OCc4cccc(CN5CCN(S(=O)(=O)C(F)(F)F)CC5)c4)cccc3C2=O)C(=O)N1 -US08906941B2,2,NC(=O)C(O)C(N)Cc1ccccc1.O=C(O)c1cccnc1-c1csc(-c2ccc(F)cc2)n1>>NC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-c1csc(-c2ccc(F)cc2)n1 -US08501750B2,1,CCc1cc2c(=O)[nH]c(=O)n(Cc3c(F)cc(-c4ccccc4C#N)cc3F)c2s1.COc1ccc(C(=O)CBr)cc1>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3c(F)cc(-c4ccccc4C#N)cc3F)c2s1 -US20080269210A1,3,CC(C)(O)c1cc2nc(Cl)nc(N3CCOCC3)c2s1.COc1ccncc1B(O)O>>COc1ccncc1-c1nc(N2CCOCC2)c2sc(C(C)(C)O)cc2n1 -US20110152245A1,2,CN1CCN(c2ccc(N=C=O)cc2)CC1.Nc1ccc(-c2cnco2)cc1>>CN1CCN(c2ccc(NC(=O)Nc3ccc(-c4cnco4)cc3)cc2)CC1 -US20040082603A1,6,COc1ccc(CN2Cc3ccc(OC)cc3C2=O)cc1>>COc1ccc2c(c1)C(=O)NC2 -US05268379,1,BrCc1ccc2ccccc2c1.COC1(C#CCO)CCOCC1>>COC1(C#CCOCc2ccc3ccccc3c2)CCOCC1 -US20110196015A1,2,CC(C)(C)CC(C)(C)N.S=C=NCCc1cccs1>>CC(C)(C)CC(C)(C)NC(=S)NCCc1cccs1 -US04147804,2,CCCCNc1c(C)cccc1C.O=C(Cl)Cl>>CCCCN(C(=O)Cl)c1c(C)cccc1C -US07829572B2,2,C[C@@H](N)Cc1ccccc1.Nc1ccnc(C(F)(F)F)c1C(=O)O>>C[C@H](Cc1ccccc1)NC(=O)c1c(N)ccnc1C(F)(F)F -US20130045986A1,2,Nc1ccc(Br)cc1O.O=C(Cl)c1ccc(C(F)F)cc1>>O=C(Nc1ccc(Br)cc1O)c1ccc(C(F)F)cc1 -US20120232056A1,6,COC(=O)c1ccc2nc(-c3ccc4[nH]ncc4c3)c(N(C)[C@@H](C)c3ccccc3)nc2c1>>C[C@@H](c1ccccc1)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc2[nH]ncc2c1 -US20150218150A1,2,CN1Cc2cc(-c3ccc(-c4cncc(N)c4)s3)ccc2C1=O.O=S(=O)(Cl)c1ccc(Cl)nc1>>CN1Cc2cc(-c3ccc(-c4cncc(NS(=O)(=O)c5ccc(Cl)nc5)c4)s3)ccc2C1=O -US20140322355A1,7,COC(=O)c1ccc(C2CCC2)c([N+](=O)[O-])c1>>COC(=O)c1ccc(C2CCC2)c(N)c1 -US20050197339A1,1,O=[N+]([O-])c1ccc(O)nc1.OCc1cccc(F)c1>>O=[N+]([O-])c1ccc(OCc2cccc(F)c2)nc1 -US20130225646A1,2,CC(C)(C)OC(=O)NC(CN)c1ccccc1C(F)(F)F.COCCn1c(-c2ccc(Cl)s2)nn(CC(=O)O)c1=O>>COCCn1c(-c2ccc(Cl)s2)nn(CC(=O)NCC(NC(=O)OC(C)(C)C)c2ccccc2C(F)(F)F)c1=O -US20090286774A1,7,CCCCCn1c(N)c(N=O)c(=O)[nH]c1=S>>CCCCCn1c(N)c(N)c(=O)[nH]c1=S -US04404214,2,COc1cccnc1C(=O)O.Nc1nnn[nH]1>>COc1cccnc1C(=O)Nc1nnn[nH]1 -US20120252779A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=C(O)c1c(F)ccc(Br)c1F>>CC(C)(C)OC(=O)N1CCN(c2ccc(F)c(C(=O)O)c2F)CC1 -US20050054710A1,9,CC(=O)N1C(=O)C(=C(O)c2cc(C)on2)c2ccccc21.ClC(Cl)(Cl)Cl>>CC(=O)N1C(=O)C(=C(Cl)c2cc(C)on2)c2ccccc21 -US05200415,6,CCOC(=O)c1c(C)nn2c(C)cccc12>>Cc1nn2c(C)cccc2c1C(=O)O -US20100240656A1,1,CCOc1cc2c(cc1Br)OCO2.Cn1c(S)nc(C(N)=O)c1N>>CCOc1cc2c(cc1Sc1nc(C(N)=O)c(N)n1C)OCO2 -US07704994B2,1,COc1cc(OC)nc(-c2ccc(Cl)nc2)n1.Oc1ccc2c(c1)CCN(C1CCC1)CC2>>COc1cc(OC)nc(-c2ccc(Oc3ccc4c(c3)CCN(C3CCC3)CC4)nc2)n1 -US20090209536A1,1,CC(C)(C)c1ccc2c(N3CCCC3)nc(Cl)nc2c1.Nc1cccc(Cl)c1>>CC(C)(C)c1ccc2c(N3CCCC3)nc(Nc3cccc(Cl)c3)nc2c1 -US07208494B2,1,BrCC1CC1.CCc1nc2c(cc1CO)C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N21>>CCc1nc2c(cc1COCC1CC1)C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N21 -US06093714,4,CCOC(=O)C#CC(O)c1ccc(NC(=O)OC(C)(C)C)cc1[N+](=O)[O-].COc1ccc(CN=[N+]=[N-])cc1>>CCOC(=O)c1c(C(O)c2ccc(NC(=O)OC(C)(C)C)cc2[N+](=O)[O-])nnn1Cc1ccc(OC)cc1 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.COc1ncc(B(O)O)cn1>>CCCNC(=O)c1nnc2c(-c3cnc(OC)nc3)cccc2c1N -US05783575,2,COC(=O)c1cc2c([nH]c3ccccc32)s1.O=C(Cl)c1ccccc1>>COC(=O)c1cc2c3ccccc3n(C(=O)c3ccccc3)c2s1 -US05202344,2,CCOC(=O)C1CN(c2ccccc2)C(=O)C1N.O=C(Cl)c1ccc(Cl)c(Cl)c1>>CCOC(=O)[C@@H]1CN(c2ccccc2)C(=O)[C@@H]1NC(=O)c1ccc(Cl)c(Cl)c1 -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1cc(C2=CCOC2)cc(C)c1Br>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(C6=CCOC6)cc5C)ccc(F)c43)ccc21 -US05589492,6,COC(=O)C(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)Sc1ccc(Cl)cc1>>CN(CCOc1ccc(CC(Sc2ccc(Cl)cc2)C(=O)O)cc1)c1nc2ccccc2o1 -US20140088076A1,2,Cc1ccc(F)cc1-c1ccc2cc(N)ncc2c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1ccc(F)cc1-c1ccc2cc(NC(=O)Oc3ccc([N+](=O)[O-])cc3)ncc2c1 -US20030212276A1,1,COc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1F.[S-]c1ccccc1>>COc1cc(Nc2c(C#N)cnc3cc(Sc4ccccc4)c(OC)cc23)c(Cl)cc1Cl -US20080125436A1,2,CCOC(=O)c1cnn(COCC[Si](C)(C)C)c(=O)c1.NN>>C[Si](C)(C)CCOCn1ncc(C(=O)NN)cc1=O -US20090270351A1,1,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(CBr)cc1.CCOP(=O)(CN)OCC>>CCOP(=O)(CNCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2NC(=O)OC(C)(C)C)cc1)OCC -US20100261702A1,1,CCI.Cc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(C)c3)no2)sc1CNC(C)C>>CCN(Cc1sc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(C)c3)no2)cc1C)C(C)C -US08030354B2,8,COc1ccc(F)c(-c2ccc(CO[Si](C)(C)C(C)(C)C)cc2CO)c1>>COc1ccc(F)c(-c2ccc(CO[Si](C)(C)C(C)(C)C)cc2C=O)c1 -US08426411B2,2,CC1CC(N)CC1c1cnc2cnc3c(ccn3COCC[Si](C)(C)C)n12.O=S(=O)(Cl)C1CC1>>CC1CC(NS(=O)(=O)C2CC2)CC1c1cnc2cnc3c(ccn3COCC[Si](C)(C)C)n12 -US04359418,2,CCC(N)CCCCCCCCC(C)(C)C(=O)O.CO>>CCC(N)CCCCCCCCC(C)(C)C(=O)OC -US04719210,2,CCOC(=O)c1ncc2[nH]c3cccc(OCc4ccccc4)c3c2c1COC.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)c1ncc2c(c1COC)c1c(OCc3ccccc3)cccc1n2S(=O)(=O)c1ccc(C)cc1 -US20120149910A1,6,CCc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc2c(c1)CCC2NC(=O)OC(C)(C)C>>CCc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc2c(c1)CCC2N -US08629270B2,2,CC(C)(C)OC(=O)N1CC(CO)C(N)(c2ccccc2)C1.O=C(N=C=S)c1ccccc1>>CC(C)(C)OC(=O)N1CC(CO)C(NC(=S)NC(=O)c2ccccc2)(c2ccccc2)C1 -US20080262040A1,2,CC(C)(C)OC(=O)N1CCC(O)CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US08993577B2,1,CC1(C)CN(C(=O)OC(C)(C)C)CCN1.O=C1CCC1>>CC(C)(C)OC(=O)N1CCN(C2CCC2)C(C)(C)C1 -US06492421B1,1,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(C)cc1.O=C(CCl)NCc1ccccc1>>COC(=O)[C@H](Cc1ccc(OCC(=O)NCc2ccccc2)cc1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(C)cc1 -US07417169B2,7,CCOC(=O)COc1ccc(-c2ccc(C(=O)OCC)cc2)cc1>>CCOC(=O)c1ccc(-c2ccc(OCCO)cc2)cc1 -US06004948,7,NS(=O)(=O)c1ccc([N+](=O)[O-])c(Sc2ccc(Cl)cc2)c1>>Nc1ccc(S(N)(=O)=O)cc1Sc1ccc(Cl)cc1 -US20150079035A1,1,CCOC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.NC1CCC(F)(F)CC1>>CCOC(=O)c1ccc(NC2CCC(F)(F)CC2)c([N+](=O)[O-])c1 -US04782160,2,COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cc([N+](=O)[O-])ccc1OCCCCN.CS(=O)(=O)Cl>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cc([N+](=O)[O-])ccc1OCCCCNS(C)(=O)=O -US20120202690A1,1,BrCc1ccccc1.Clc1nc(Cl)c2nc[nH]c2n1>>Clc1nc(Cl)c2ncn(Cc3ccccc3)c2n1 -US05489591,7,CN(c1ccc([N+](=O)[O-])cc1)c1nc(N2CCOCC2)nc(-n2ccnc2)n1>>CN(c1ccc(N)cc1)c1nc(N2CCOCC2)nc(-n2ccnc2)n1 -US20110071150A1,3,CCOC(=O)n1c(OS(=O)(=O)C(F)(F)F)cc2cc(-c3sc(-c4ccccc4)nc3C)ccc21.Cc1ncccc1B(O)O>>CCOC(=O)n1c(-c2cccnc2C)cc2cc(-c3sc(-c4ccccc4)nc3C)ccc21 -US20100179194A1,9,Cc1ccc(C=O)cc1[N+](=O)[O-].NO>>Cc1ccc(C=NO)cc1[N+](=O)[O-] -US20130150339A1,3,COc1cc(-c2cc(F)cc(F)c2)ccc1B(O)O.O=S(=O)(Oc1c(F)c(F)c(F)c(F)c1F)c1ccc2c(Cl)nccc2c1>>COc1cc(-c2cc(F)cc(F)c2)ccc1-c1nccc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12 -US05607939,7,O=C1c2ccccc2CCC12CCCCN2>>OC1c2ccccc2CCC12CCCCN2 -US08455479B2,2,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)c(F)cc1F.CN1C(=O)CNCc2ccccc21>>CN1C(=O)CN(C(=O)C[C@@H](Cc2cc(F)c(F)cc2F)NC(=O)OC(C)(C)C)Cc2ccccc21 -US20110077305A1,1,CC(=O)Cl.CC(C#Cc1cccc(S(=O)(=O)Nc2ccc(F)cc2)c1)NO>>CC(=O)N(O)C(C)C#Cc1cccc(S(=O)(=O)Nc2ccc(F)cc2)c1 -US20100267706A1,1,CN(C)CCCOc1ccc(C=O)cc1.Oc1c(Cl)cc(-c2cc(N3CCNCC3)c(OCCc3ccc(Cl)cc3)nn2)cc1Cl>>CN(C)CCCOc1ccc(CN2CCN(c3cc(-c4cc(Cl)c(O)c(Cl)c4)nnc3OCCc3ccc(Cl)cc3)CC2)cc1 -US07790756B2,7,CC(C)c1cc(NC(=O)Nc2cc(Oc3ccc([N+](=O)[O-])nc3)ccc2F)n(-c2ccc3ncccc3c2)n1>>CC(C)c1cc(NC(=O)Nc2cc(Oc3ccc(N)nc3)ccc2F)n(-c2ccc3ncccc3c2)n1 -US07834019B2,1,C1CSCCN1.Cc1cc([N+](=O)[O-])ccc1F>>Cc1cc([N+](=O)[O-])ccc1N1CCSCC1 -US20070249670A1,5,CC(C)(C)OC(=O)c1ccsc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)c1ccsc1NC(=O)C(F)(F)F -US20140018347A1,6,CC(=O)Nc1nc2cc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)CCO4)cnc2s1>>CC(=O)Nc1nc2cc(-c3ccc4c(c3)CNCCO4)cnc2s1 -US08148391B2,1,Clc1ncc(Cl)c(Cl)n1.N#CCOc1ccccc1N>>N#CCOc1ccccc1Nc1nc(Cl)ncc1Cl -US20100063056A1,2,COc1ccc(CN)cc1OC.O=C(O)c1cc(Cl)cnc1-c1cccnc1>>COc1ccc(CNC(=O)c2cc(Cl)cnc2-c2cccnc2)cc1OC -US04474786,2,CC(=O)Cl.Nc1cc2c([nH]c1=O)OCc1ccccc1-2>>CC(=O)Nc1cc2c([nH]c1=O)OCc1ccccc1-2 -US20080200535A1,7,O=Cc1ccc(OCc2cc(-c3ccccc3)c(C(F)(F)F)s2)cc1>>OCc1ccc(OCc2cc(-c3ccccc3)c(C(F)(F)F)s2)cc1 -US20080280917A1,1,COc1ccc2c(Cl)ccnc2c1.O=c1ncc(-c2ccccc2)cn1CCO>>COc1ccc2c(OCCn3cc(-c4ccccc4)cnc3=O)ccnc2c1 -US06624159B2,2,CCOC(=O)c1cn2c3c(cc(I)cc3c1=O)N(C)C(=O)C2.NCc1ccc(Cl)cc1>>CN1C(=O)Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(I)cc1c32 -US04710507,2,CCO/C=C/C(=O)Cl.Cc1cc(Br)ccc1N>>CCO/C=C/C(=O)Nc1ccc(Br)cc1C -US06743785B2,7,COC(=O)C1=Cc2cccc3ccn(c23)C1>>COC(=O)C1Cc2cccc3ccn(c23)C1 -US05686433,3,CCOC(=O)CC(=O)C(C)C.O=Cc1ccc(F)cc1>>CCOC(=O)C(=Cc1ccc(F)cc1)C(=O)C(C)C -US06063782,1,C=C(C)Cn1c(C)c(C)c2cnnc(Cl)c21.OCc1ccc(F)cc1>>C=C(C)Cn1c(C)c(C)c2cnnc(OCc3ccc(F)cc3)c21 -US20090137548A1,3,COC(=O)c1ccc(Br)c(C)c1.COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1-c1ccc(C(F)(F)F)cc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C>>COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3CN3C(=O)O[C@H](c4cc(C(F)(F)F)cc(C(F)(F)F)c4)[C@@H]3C)c2)c(C)c1 -US20110053931A1,1,COc1cc2nccc(Cl)c2cc1OC.O=c1c(-c2ccc(O)c(F)c2)cncn1Cc1c(F)cc(Cl)cc1F>>COc1cc2nccc(Oc3ccc(-c4cncn(Cc5c(F)cc(Cl)cc5F)c4=O)cc3F)c2cc1OC -US20150152108A1,3,Cc1ccc(B(O)O)c(C)n1.O=C(Nc1cnccn1)N1c2nc(Cl)ccc2N2CC[C@H]1C2>>Cc1ccc(-c2ccc3c(n2)N(C(=O)Nc2cnccn2)[C@H]2CCN3C2)c(C)n1 -US06630591B2,3,CCOP(=O)(CC#N)OCC.O=Cc1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1>>N#CC=Cc1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1 -US06147061,7,O=C(c1ccccc1)c1ccc(CBr)cc1>>BrCc1ccc(Cc2ccccc2)cc1 -US20110053931A1,2,COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCOCC1.O=C(O)C1CCCN(c2ccc(F)cc2)C1=O>>COc1cc2c(Oc3ccc(NC(=O)C4CCCN(c5ccc(F)cc5)C4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 -US07034015B2,1,O=C1COCC(=O)N1.OCCc1ccccc1Br>>O=C1COCC(=O)N1CCc1ccccc1Br -US05015644,7,CCN(CC)c1ccc(C2(C#N)CCCC2)cc1>>CCN(CC)c1ccc(C2(CN)CCCC2)cc1 -US05051413,1,CCOC(=O)C(N)/C=C(\C)CP(=O)(O)O.O=Cc1ccccc1>>CCOC(=O)C(/C=C(\C)CP(=O)(O)O)NCc1ccccc1 -US20130274469A1,1,CCOC(=O)c1cc(Br)c(O)nc1C.Cc1onc(-c2ccccc2)c1CO>>CCOC(=O)c1cc(Br)c(OCc2c(-c3ccccc3)noc2C)nc1C -US20090298878A1,1,CI.O=c1cccc(C(ON=C2CCNCC2)S(=O)(=O)c2ccc(OC(F)(F)F)cc2)[nH]1>>Cn1c(C(ON=C2CCNCC2)S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cccc1=O -US06200998B1,7,C=CCc1c(O)ccc2c(CCc3ccccc3)coc12>>CCCc1c(O)ccc2c(CCc3ccccc3)coc12 -US20060264460A1,2,CO.Nc1ccc([N+](=O)[O-])cc1C(=O)O>>COC(=O)c1cc([N+](=O)[O-])ccc1N -US20130315874A1,2,O=S(=O)(Cl)c1ccccc1.[N-]=[N+]=NCCN>>[N-]=[N+]=NCCNS(=O)(=O)c1ccccc1 -US20060074119A1,1,COC(=O)c1sc(-n2cnc3cc(Cl)c(Cl)cc32)cc1O.OCc1cccs1>>COC(=O)c1sc(-n2cnc3cc(Cl)c(Cl)cc32)cc1OCc1cccs1 -US20110268694A1,2,CCc1csc([C@@H](N)Cc2ccc([N+](=O)[O-])cc2)n1.O=C(O)CCC(=O)c1ccccc1>>CCc1csc(C(Cc2ccc([N+](=O)[O-])cc2)NC(=O)CCC(=O)c2ccccc2)n1 -US04562281,2,CCC(=O)Cl.Cc1cc(Cc2cc(C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1>>CCC(=O)Oc1c(Cc2cc(C)cc(C(C)(C)C)c2O)cc(C)cc1C(C)(C)C -US09000006B2,3,CCOC(=O)c1ncc2cc(Br)sc2c1O.OB(O)c1cccc(C(F)(F)F)c1>>CCOC(=O)c1ncc2cc(-c3cccc(C(F)(F)F)c3)sc2c1O -US05130323,6,COC(=O)CCC/C=C\[C@@H]1C[C@@H](NC(=O)OCc2ccccc2)CN1Cc1ccccc1>>COC(=O)CCC/C=C\[C@@H]1C[C@@H](N)CN1Cc1ccccc1 -US20070249670A1,2,CC(C)(C)OC(=O)c1cc(Cc2ccccc2)sc1N.O=C=Nc1c(Cl)cccc1Cl>>CC(C)(C)OC(=O)c1cc(Cc2ccccc2)sc1NC(=O)Nc1c(Cl)cccc1Cl -US20140274688A1,6,CCOC(=O)/C(C#N)=C\c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>N#C/C(=C/c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1)C(=O)O -US20050272889A1,1,C=C(C)CCl.CNCCO>>C=C(C)CN(C)CCO -US20080305169A1,2,COc1ccc2c(c1)NCCO2.O=C(Cl)c1cc(Cl)c(O)c(Cl)c1>>COc1ccc2c(c1)N(C(=O)c1cc(Cl)c(O)c(Cl)c1)CCO2 -US20130158075A1,6,CC(C(=O)OC(C)(C)C)N1CCC(c2ncc(-c3ccc(NC(=O)Nc4cc(F)c(F)cc4F)cc3)s2)CC1>>CC(C(=O)O)N1CCC(c2ncc(-c3ccc(NC(=O)Nc4cc(F)c(F)cc4F)cc3)s2)CC1 -US20150023913A1,6,O=C(O)C1(COCc2ccccc2)CCCO1>>O=C(O)C1(CO)CCCO1 -US20090082358A1,2,FC(F)(F)c1ccc(C2NCCc3ccncc32)cc1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)N1CCc2ccncc2C1c1ccc(C(F)(F)F)cc1 -US20100120797A1,1,Cc1n[nH]cc1Cl.Cn1cnc2c(Nc3ccc(Cl)cc3)nc(Cl)nc21>>Cc1nn(-c2nc(Nc3ccc(Cl)cc3)c3ncn(C)c3n2)cc1Cl -US05753648,2,O=C(Cl)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1Cl.c1ccc2c(c1)Cn1cccc1CN2>>O=C(Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)c(Cl)c1)c1ccccc1-c1ccccc1 -US08058045B2,2,CC(C)(C)OC(=O)N1CCC(F)(CO)CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC2(F)CCN(C(=O)OC(C)(C)C)CC2)cc1 -US05075319,1,CCOC(=O)C(=CNC1CC1)C(=O)c1c(F)c(F)c(Br)c(F)c1F>>CCOC(=O)c1cn(C2CC2)c2c(F)c(Br)c(F)c(F)c2c1=O -US06197967B1,2,COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.NN>>CC1(C)OB(c2ccc(C(=O)NN)cc2)OC1(C)C -US05834468,6,CCN(CCc1cc(Br)ccc1OCc1ccccc1)c1ccc(C(=O)OC(C)(C)C)cn1>>CCN(CCc1cc(Br)ccc1OCc1ccccc1)c1ccc(C(=O)O)cn1 -US06225320B1,2,CC(=O)OC(=O)C(F)(F)F.COc1ccc(N)nc1Br>>COc1ccc(NC(=O)C(F)(F)F)nc1Br -US08148531B2,1,CC(=O)Nc1ccc(O)cc1.COc1cc2c(Cl)ccnc2cc1OCc1ccccc1>>COc1cc2c(Oc3ccc(NC(C)=O)cc3)ccnc2cc1OCc1ccccc1 -US05346881,6,CC(C)(C)OC(=O)Nc1c(F)ccc2c1OC(C)(C)O2>>CC1(C)Oc2ccc(F)c(N)c2O1 -US04431652,4,NC(=S)c1ccc(Cl)c(Cl)c1.O=C(CCl)CCl>>ClCc1csc(-c2ccc(Cl)c(Cl)c2)n1 -US20110039857A1,6,Cc1cccc(-c2sc(C3CC3)nc2C(=O)N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)c1>>Cc1cccc(-c2sc(C3CC3)nc2C(=O)N2CCC[C@@H](N)C2)c1 -US07169777B2,6,COC(=O)C(Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1Cc2ccccc2CC1C(=O)NC(Cc1ccc(Cl)cc1)C(=O)O -US06992085B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCN1CCN2CCCCC2C1>>Cc1ccc(S(=O)(=O)OCCCN2CCN3CCCCC3C2)cc1 -US20150239908A1,6,C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1>>C[C@H]1C[C@H]2CSC(N)=N[C@@]2(c2ccc(F)cc2F)CO1 -US07348349B2,3,CCOCC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1.Cc1cc(OCc2ccccc2)cc(C)c1C=O>>CCO[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](O)c1c(C)cc(OCc2ccccc2)cc1C -US05186735,2,CC(C=CCO)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1.NC(=O)c1ccc(C(=O)O)cc1>>CC(C=CCOC(=O)c1ccc(C(N)=O)cc1)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1 -US05602151,9,COc1ccc(Oc2ccccc2)cc1C=O.NO>>COc1ccc(Oc2ccccc2)cc1C=NO -US20140088080A1,6,Cc1nc2c(OCC3CCCCC3)cccn2c1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1>>Cc1nc2c(OCC3CCCCC3)cccn2c1C(=O)NC1CCNCC1 -US08877780B2,2,NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccccn1>>O=C1CCC(N2Cc3cc(CNC(=O)c4ccccn4)ccc3C2=O)C(=O)N1 -US07417050B2,1,CC[Sn](Br)(CC)CC.c1cocn1>>CC[Sn](CC)(CC)c1ncco1 -US07858652B2,7,CCOC(=O)c1ncn(COCC[Si](C)(C)C)c1F>>C[Si](C)(C)CCOCn1cnc(CO)c1F -US20090069340A1,10,CCn1c(C)c(Cl)c(=O)n1-c1ccc(Cl)cc1.O=C1CCC(=O)N1Br>>CCn1c(CBr)c(Cl)c(=O)n1-c1ccc(Cl)cc1 -US04652652,2,CCOC(=O)C(C(=O)OCC)c1csc(N)n1.O=CO>>CCOC(=O)C(C(=O)OCC)c1csc(NC=O)n1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCCC1.Oc1cccc2[nH]ccc12>>COc1cc2c(Oc3cccc4[nH]ccc34)ncnc2cc1OCCCN1CCCCC1 -US05395836,1,CC(=O)CBr.CCCn1c(N)c(NC(=O)C23CC4CC(CC2C4)C3)c(=O)[nH]c1=O>>CCCn1c(N)c(NC(=O)C23CC4CC(CC2C4)C3)c(=O)n(CC(C)=O)c1=O -US20090186900A1,6,COc1ccc(-c2ccc(C(C)=O)cc2C)cc1>>CC(=O)c1ccc(-c2ccc(O)cc2)c(C)c1 -US20070082912A1,6,CCOC(=O)c1cccc(-n2c(C)ccc2-c2ccccc2OCc2ccc(Cl)c(Cl)c2)c1>>Cc1ccc(-c2ccccc2OCc2ccc(Cl)c(Cl)c2)n1-c1cccc(C(=O)O)c1 -US20070225292A1,2,CC(C)(C)OC(=O)N1CCCCC1CN.Nc1cccnc1C(=O)O>>CC(C)(C)OC(=O)N1CCCCC1CNC(=O)c1ncccc1N -US20150197527A1,2,NC1CCCCCCC1.O=C(O)CSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccccc1>>O=C(CSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccccc1)NC1CCCCCCC1 -US04209521,3,C=O.COc1ccc(C(=O)NC(=O)NC2CCNCC2)cc1.c1ccc2[nH]ccc2c1>>COc1ccc(C(=O)NC(=O)NC2CCN(Cc3c[nH]c4ccccc34)CC2)cc1 -US07105671B2,2,CS(=O)(=O)c1ccc(C(CC2CCOCC2)C(=O)O)cc1Cl.Nc1cnccn1>>CS(=O)(=O)c1ccc(C(CC2CCOCC2)C(=O)Nc2cnccn2)cc1Cl -US07994185B2,2,CC(C)(C)c1nc(-c2cccc(N)c2F)c(-c2ccnc(N)n2)s1.O=S(=O)(Cl)c1cccs1>>CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3cccs3)c2F)c(-c2ccnc(N)n2)s1 -US07482350B2,1,C[C@@H]1CNCCN1.Cc1ccc(C(C)C)cc1OCc1c(C)nc(-c2c(C)cccc2C)nc1Cl>>Cc1ccc(C(C)C)cc1OCc1c(C)nc(-c2c(C)cccc2C)nc1N1CCN[C@H](C)C1 -US20150141650A1,6,CC(C)(C)OC(=O)N1C2CC3CC1CC(OCC1CC1)(C3)C2>>C1CC1COC12CC3CC(C1)NC(C3)C2 -US08415381B2,6,N#CC1(CNc2nc(OCc3ccccc3)ccc2F)CCOCC1>>N#CC1(CNc2nc(O)ccc2F)CCOCC1 -US20130060063A1,1,BrCc1ccccc1.COC(=O)c1cc(Br)c(F)cc1O>>COC(=O)c1cc(Br)c(F)cc1OCc1ccccc1 -US06727245B2,4,NC(N)=S.O=C(CBr)c1cccc([N+](=O)[O-])c1>>Nc1nc(-c2cccc([N+](=O)[O-])c2)cs1 -US07196202B2,8,CCCSc1nc2ccc(OCCCCCC(=O)OC)cc2n1-c1ccc(C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCS(=O)c1nc2ccc(OCCCCCC(=O)OC)cc2n1-c1ccc(C)cc1 -US08809525B2,1,C1CCC2NCCCC2C1.Nc1nnc(Br)c(-c2ccccc2)n1>>Nc1nnc(N2CCCC3CCCCC32)c(-c2ccccc2)n1 -US20080221178A1,4,C=CCC(C)(C)C(=O)O.Nc1cc(NS(=O)(=O)c2ccccc2)ccc1NCC1CCCCC1>>C=CCC(C)(C)c1nc2cc(NS(=O)(=O)c3ccccc3)ccc2n1CC1CCCCC1 -US05635485,8,OCc1csc(-c2ccccn2)n1>>O=Cc1csc(-c2ccccn2)n1 -US20060063791A1,6,CN1CCC2(CC1)C(=O)Nc1ccc(NC(=O)OC(C)(C)C)cc12>>CN1CCC2(CC1)C(=O)Nc1ccc(N)cc12 -US04851526,9,CS(=O)(=O)OC1CCCCC1N(Cc1ccccc1)Cc1ccccc1.[C-]#N>>N#CC1CCCCC1N(Cc1ccccc1)Cc1ccccc1 -US05010195,9,CSc1nc(F)cc(F)n1.NN>>CSc1nc(F)cc(NN)n1 -US07569579B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC[C@@]1(c2ccccc2)C[C@H]1COCc1ccccc1>>CC(C)(C)OC(=O)NC[C@@]1(c2ccccc2)C[C@H]1COCc1ccccc1 -USRE044638E1,3,C#C[Si](C)(C)C.Cc1cccc2nc(C(C)Nc3ncnc4c3ncn4COCC[Si](C)(C)C)n(-c3cccc(OS(=O)(=O)C(F)(F)F)c3)c(=O)c12>>Cc1cccc2nc(C(C)Nc3ncnc4c3ncn4COCC[Si](C)(C)C)n(-c3cccc(C#C[Si](C)(C)C)c3)c(=O)c12 -US04243410,2,CC(Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)C(=O)Cl.COCCN>>COCCNC(=O)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1 -US07211685B2,7,Cc1ccccc1C(=O)C1CC1>>Cc1ccccc1[C@H](O)C1CC1 -US20120190543A1,7,O=[N+]([O-])c1ccc(-c2ccnc(-c3ccc(C(F)(F)F)cc3)n2)cc1>>Nc1ccc(-c2ccnc(-c3ccc(C(F)(F)F)cc3)n2)cc1 -US20150158878A1,6,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])OC(F)(F)O2>>Nc1cc2c(cc1[N+](=O)[O-])OC(F)(F)O2 -US20090105212A1,1,CN.COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(CCl)cc3)c2n1>>CNCc1ccc(Cn2c(=O)[nH]c3c(N)nc(OCCOC)nc32)cc1 -US20110152315A1,1,C#CCBr.COC(=O)CCc1ccc(C#Cc2cccc(O)c2)cc1>>C#CCOc1cccc(C#Cc2ccc(CCC(=O)OC)cc2)c1 -US20100048570A1,6,CCOC(=O)[C@@H](Oc1ccc(CNC(=O)[C@@H]2SCCN2C(=O)C[C@@H](Cc2cc(F)c(F)cc2F)NC(=O)OC(C)(C)C)cc1)C(C)C>>CC(C)[C@H](Oc1ccc(CNC(=O)[C@@H]2SCCN2C(=O)C[C@@H](Cc2cc(F)c(F)cc2F)NC(=O)OC(C)(C)C)cc1)C(=O)O -US08313669B2,1,OCCCBr.Oc1cccc(-c2cccc(O)c2)c1>>OCCCOc1cccc(-c2cccc(O)c2)c1 -US20150065715A1,1,Cc1c(C(N)=O)cnn1-c1ccc(Cl)cc1.OC1CCN(c2ncc(Br)cc2Cl)CC1>>Cc1c(C(=O)Nc2cnc(N3CCC(O)CC3)c(Cl)c2)cnn1-c1ccc(Cl)cc1 -US07547779B2,1,CC(C)C(=O)O.Nc1cccc(Oc2cc3c(cn2)nc(-c2nonc2N)n3-c2ccc(O)cc2)c1>>CC(C)C(=O)Oc1ccc(-n2c(-c3nonc3N)nc3cnc(Oc4cccc(N)c4)cc32)cc1 -US08129376B2,2,Brc1ccccc1NC1CCNCC1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>O=C(NCC(=O)N1CCC(Nc2ccccc2Br)CC1)c1cc(-c2ccccc2)[nH]n1 -US04206142,2,N=C(N)c1ccc(C=Cc2ccccc2)cc1.O=[N+]([O-])c1ccc(C=CS(=O)(=O)Cl)cc1>>N=C(NS(=O)(=O)C=Cc1ccc([N+](=O)[O-])cc1)c1ccc(C=Cc2ccccc2)cc1 -US20140194431A1,6,CC(C)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1nc(CC2(c3ccc(Cl)c(Cl)c3)CCCC2)nc(O)c1OCc1ccccc1>>CC(C)N(CCO)C(=O)c1nc(CC2(c3ccc(Cl)c(Cl)c3)CCCC2)nc(O)c1OCc1ccccc1 -US08809525B2,1,Nc1nnc(Br)c(-c2ccccc2)n1.Oc1cc(F)cc(F)c1>>Nc1nnc(Oc2cc(F)cc(F)c2)c(-c2ccccc2)n1 -US20110021498A1,2,CC(C)(C)OC(=O)n1c(-c2cc(C(=O)O)cn(COCC[Si](C)(C)C)c2=O)cc2ccccc21.COc1ccc(Cn2cc(N)cn2)cc1>>COc1ccc(Cn2cc(NC(=O)c3cc(-c4cc5ccccc5n4C(=O)OC(C)(C)C)c(=O)n(COCC[Si](C)(C)C)c3)cn2)cc1 -US20110150942A1,1,CN(C)CC[C@H](O)c1cccs1.Fc1cccc2ccccc12>>CN(C)CC[C@H](Oc1cccc2ccccc12)c1cccs1 -US08557936B2,3,COc1c(Br)cccc1Br.OB(O)c1ccccc1>>COc1c(Br)cccc1-c1ccccc1 -US08022062B2,6,COC(=O)c1ccc(C#N)cc1F>>N#Cc1ccc(C(=O)O)c(F)c1 -US08759537B2,4,CC(C)(C)C(=O)NCc1ccc(Cl)c(N=C=S)c1Cl.Nc1cc(OCC(F)F)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1N>>CC(C)(C)C(=O)NCc1ccc(Cl)c(Nc2nc3cc(C(=O)N[C@@H]4CC[C@@H](C(F)(F)F)CC4)c(OCC(F)F)cc3[nH]2)c1Cl -US20060084661A1,2,CN1CCNCC1.O=C(O)c1cccc([N+](=O)[O-])c1O>>CN1CCN(C(=O)c2cccc([N+](=O)[O-])c2O)CC1 -US08940724B2,1,C1CSCCN1.O=[N+]([O-])c1cc(Cl)cnc1N1CCOCC1>>O=[N+]([O-])c1cc(N2CCSCC2)cnc1N1CCOCC1 -US20120077781A1,7,Cc1cc([N+](=O)[O-])c(NCCCCCCC(=O)OC(C)(C)C)cc1Cl>>Cc1cc(N)c(NCCCCCCC(=O)OC(C)(C)C)cc1Cl -US08188093B2,7,COC(=O)c1cnc(C#Cc2ccccn2)c(-c2ccc(Cl)cc2)c1>>COC(=O)c1cnc(CCc2ccccn2)c(-c2ccc(Cl)cc2)c1 -US20060264415A1,7,COC(=O)c1ccc(COCC(=O)NCCCCCC(=O)Nc2cccc(-c3ccccc3)c2)cc1>>O=C(COCc1ccc(CO)cc1)NCCCCCC(=O)Nc1cccc(-c2ccccc2)c1 -US20070270421A1,2,CN(C)CC1CCN(C(=O)Nc2cc(Oc3ccc(N)cc3F)ncn2)CC1.O=C(Cc1ccc(F)cc1)N=C=S>>CN(C)CC1CCN(C(=O)Nc2cc(Oc3ccc(NC(=S)NC(=O)Cc4ccc(F)cc4)cc3F)ncn2)CC1 -US20060142570A1,2,Nc1nc2ccc([N+](=O)[O-])cc2o1.O=C(Cl)c1ccccc1>>O=C(Nc1nc2ccc([N+](=O)[O-])cc2o1)c1ccccc1 -US07253198B2,1,COC(=O)c1cc(NC(=O)CCCCCl)cc([N+](=O)[O-])c1>>COC(=O)c1cc(N2CCCCC2=O)cc([N+](=O)[O-])c1 -US20140155391A1,6,CN(C)CCN(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1>>CN(C)CCNS(=O)(=O)c1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1 -US07749997B2,6,COC(=O)C12CCCC(C(=O)OC)(CC1)CC2>>COC(=O)C12CCCC(C(=O)O)(CC1)CC2 -US20120189548A1,6,CCN(CC)C(=O)Cc1c(-c2ccc(OC)cc2)nn2c(C)cc(C)nc12>>CCN(CC)C(=O)Cc1c(-c2ccc(O)cc2)nn2c(C)cc(C)nc12 -US07294624B2,1,CC(C)=O.Cc1cc(COc2ccc(C(=O)NCC3(N4CCNCC4)C(=O)NC(=O)NC3=O)cc2)c2ccccc2n1>>Cc1cc(COc2ccc(C(=O)NCC3(N4CCN(C(C)C)CC4)C(=O)NC(=O)NC3=O)cc2)c2ccccc2n1 -US08173650B2,6,CN(Cc1ccccc1)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1>>CNc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1 -US20100137313A1,6,CC(C)(C)OC(=O)CS(=O)(=O)c1cccc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)c1>>O=C(O)CS(=O)(=O)c1cccc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)c1 -US08268822B2,1,C=CCOC(=O)N(Cc1cccc(-c2ccnc(Cl)n2)c1)C(C)(C)C.NCCc1ccc(O)cc1>>C=CCOC(=O)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)cc3)n2)c1)C(C)(C)C -US08129376B2,2,Fc1ccc(Cl)c(OC2CCNCC2)c1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>O=C(NCC(=O)N1CCC(Oc2cc(F)ccc2Cl)CC1)c1cc(-c2ccccc2)[nH]n1 -US20150011589A1,1,CN.O=C(O)c1ccc(Cl)c([N+](=O)[O-])c1>>CNc1ccc(C(=O)O)cc1[N+](=O)[O-] -US20080039459A1,1,C1COCCN1.Clc1nc(Cl)c2oc(-c3ccccc3)cc2n1>>Clc1nc(N2CCOCC2)c2oc(-c3ccccc3)cc2n1 -US20150038488A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1Nc2cc(Br)ccc2C12CCNCC2>>CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)Nc1cc(Br)ccc12 -US07652058B2,1,CC(C)=O.Cc1cc(F)ccc1[C@@H]1[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC[C@@H]2CNC[C@H]21>>Cc1cc(F)ccc1[C@@H]1[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC[C@@H]2CN(C(C)C)C[C@H]21 -US20130131075A1,2,NCc1ccc(Nc2ccc(F)cc2C(F)(F)F)cn1.O=C(NC1(C(=O)O)CC1)c1cnc2[nH]cnc2c1>>O=C(NC1(C(=O)NCc2ccc(Nc3ccc(F)cc3C(F)(F)F)cn2)CC1)c1cnc2[nH]cnc2c1 -US07582761B2,1,C1CNCCN1.Oc1cccc2ccc(Cl)nc12>>Oc1cccc2ccc(N3CCNCC3)nc12 -US20080267981A1,1,COC(=O)c1cc2ccccc2[nH]1.O=C1c2ccccc2C(=O)N1CCCBr>>COC(=O)c1cc2ccccc2n1CCCN1C(=O)c2ccccc2C1=O -US20150023913A1,9,CCOC(=O)C(F)(F)C1(O)CCCCO1>>CCOC(=O)C(F)(F)C1CCCCO1 -US07507841B2,3,Brc1ccccn1.Cc1c(NC(=O)CC(C)(C)C)c(C)c2c(c1B(O)O)OCC2c1ccc(C(C)C)cc1>>Cc1c(NC(=O)CC(C)(C)C)c(C)c2c(c1-c1ccccn1)OCC2c1ccc(C(C)C)cc1 -US20040192735A1,2,Cc1ccnc(C=Cc2nn(C3CCCCO3)c3cc(Nc4ccccc4C(=O)O)ccc23)c1.NCC#CC1CC1>>Cc1ccnc(C=Cc2nn(C3CCCCO3)c3cc(Nc4ccccc4C(=O)NCC#CC4CC4)ccc23)c1 -US20080027070A1,1,Brc1ccccc1.Nc1ncc([N+](=O)[O-])cn1>>O=[N+]([O-])c1cnc(Nc2ccccc2)nc1 -US04054663,2,CCNCC.Cc1cc(C(=O)O)cc([N+](=O)[O-])n1>>CCN(CC)C(=O)c1cc(C)nc([N+](=O)[O-])c1 -US05563158,3,COC(=O)Cl.Cc1cc(Br)cs1>>COC(=O)c1csc(C)c1 -US08569319B2,1,Nc1nccc(Cl)c1I.Oc1cc(F)ccc1F>>Nc1nccc(Oc2cc(F)ccc2F)c1I -US06057357,6,COC(=O)Cc1cc2ccccc2o1>>O=C(O)Cc1cc2ccccc2o1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nncn4CC(C)C)cc2)CCN3CCC)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nncn4CC(C)C)cc2)CCN3CCC)cc1 -US05629406,2,CC(C)(C)NC(=O)[C@@H]1C[C@H](Cl)CN1C(=O)[C@@H](O)[C@@H](N)Cc1ccccc1.NS(=O)(=O)CC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(C)(C)NC(=O)[C@@H]1C[C@H](Cl)CN1C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCS(N)(=O)=O)NC(=O)OCc1ccccc1 -US20100311966A1,1,CCOC(=O)c1cccc2nc(N3CC[C@H](NC(=O)c4nc(Cl)c(CC)[nH]4)[C@H](N)C3)sc12.O=C1CCOCC1>>CCOC(=O)c1cccc2nc(N3CC[C@H](NC(=O)c4nc(Cl)c(CC)[nH]4)[C@H](NC4CCOCC4)C3)sc12 -US20070213364A1,6,COC(=O)CCc1ccc(OCc2cccc(-c3csc4ccccc34)c2)cc1>>O=C(O)CCc1ccc(OCc2cccc(-c3csc4ccccc34)c2)cc1 -US05668176,6,COC(=O)c1ccc(OC(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)c(CC(C)C)c1>>CC(C)Cc1cc(C(=O)O)ccc1OC(C(=O)NS(=O)(=O)c1ccc(C(C)C)cc1)c1ccc2c(c1)OCO2 -US20020198197A1,2,CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)c(C(F)(F)F)cc1N.CCOC(=O)CC(=O)c1cccc(-n2cnnc2)c1>>CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-n2cnnc2)c1 -US20040229870A1,1,Cc1cc(C)c(-n2c(C)nc3c(NCCCl)cc(C)nc32)c(C)c1.NC1CCCCC1>>Cc1cc(C)c(-n2c(C)nc3c(NCCNC4CCCCC4)cc(C)nc32)c(C)c1 -US20110152233A1,6,CC(C)(C)OC(=O)NC1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)NC1CNCC1c1ccc(Cl)c(Cl)c1 -US05466701,3,CC(C)c1ccccc1Br.CCN(CC)C(=O)Cl>>CCN(CC)C(=O)c1ccccc1C(C)C -US08486939B2,1,CNC.O=[N+]([O-])c1ccc(Cl)nc1>>CN(C)c1ccc([N+](=O)[O-])cn1 -US20090143354A1,6,CC(C)(C)OC(=O)CNc1ccc2c(NC(=O)CC3CCCCC3)c(Cl)ccc2n1>>O=C(O)CNc1ccc2c(NC(=O)CC3CCCCC3)c(Cl)ccc2n1 -US05763450,6,COC(=O)CCNc1cccc(-c2cc(Cc3cnc(N)nc3N)cc(OC)c2OC)c1>>COc1cc(Cc2cnc(N)nc2N)cc(-c2cccc(NCCC(=O)O)c2)c1OC -US20070265281A1,6,COC(=O)CN(CC1CCCCC1)C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N(CC(=O)O)CC1CCCCC1 -US05750767,3,O=C(Cl)CCc1ccc2ccccc2c1Br>>O=C1CCc2c1cc1ccccc1c2Br -US20090270350A1,1,COC(=O)c1ccc(CBr)cc1.Cc1cc(OCc2ccccc2C#N)c(Br)c(=O)[nH]1>>COC(=O)c1ccc(Cn2c(C)cc(OCc3ccccc3C#N)c(Br)c2=O)cc1 -US04048223,1,ICCCC1c2ccccc2C=Cc2ccccc21.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCCC1c2ccccc2C=Cc2ccccc21 -US08658636B2,6,COC(=O)c1c(CN2CCC(N3CCC(F)(F)C3)CC2)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc12>>CS(=O)(=O)c1ccc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(N4CCC(F)(F)C4)CC3)c(C(=O)O)c2c1 -US05541195,6,O=C(c1c(Cl)cccc1Cl)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1>>O=C(c1c(Cl)cccc1Cl)N1CCC(NCc2ccnc3ccccc23)CC1Cc1ccccc1 -US20150045323A1,6,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OCCOc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1S(=O)(=O)C(C)(C)C>>CC(C)[C@H](N)C(=O)OCCOc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1S(=O)(=O)C(C)(C)C -US05244889,2,CC(=O)OCCN.CC(=O)SC[C@H]1CCCCCC[C@H](C(=O)O)NC1=O>>CC(=O)OCCNC(=O)[C@H]1CCCCCC[C@H](CSC(C)=O)C(=O)N1 -US20150004181A1,1,CI.CN1CCC(OC(c2cccc(I)c2)c2nc3ccccc3[nH]2)CC1>>CN1CCC(OC(c2cccc(I)c2)c2nc3ccccc3n2C)CC1 -US20100152160A1,6,CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)nc3)CC2)Oc2cc(OCc3ccccc3)c(Cl)cc21>>CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)nc3)CC2)Oc2cc(O)c(Cl)cc21 -US04219499,1,CO.O=S(=O)(O)N(CCl)C1CCCCC1>>COCN(C1CCCCC1)S(=O)(=O)O -US05118694,1,CSc1ccc(O)c(C(C=C(C)C)c2cccc[n+]2[O-])c1>>CSc1ccc2c(c1)C(c1cccc[n+]1[O-])CC(C)(C)O2 -US04673746,6,CCOC(=O)COc1ccc2c(-c3ccc(C)cc3)noc2c1Cl>>Cc1ccc(-c2noc3c(Cl)c(OCC(=O)O)ccc23)cc1 -US05332739,1,COc1cc([N+](=O)[O-])ccc1O.Cn1c(N2CCN(CCCO)CC2)cc(=O)n(C)c1=O>>COc1cc([N+](=O)[O-])ccc1OCCCN1CCN(c2cc(=O)n(C)c(=O)n2C)CC1 -US20080161295A1,1,CN.Cc1cccc(N2c3ccccc3CN(CCCCl)S2(=O)=O)c1>>CNCCCN1Cc2ccccc2N(c2cccc(C)c2)S1(=O)=O -US07834197B2,1,CC(C)N1CCCC1.CCOCCl>>CCOC[N+]1(C(C)C)CCCC1 -US06169095A,2,CC(=O)OC(C)=O.Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)c2n1>>CC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl -US20100016318A1,8,CC(C)NC(=O)c1ccccc1Nc1nc(Nc2ccc(CO)cc2)ncc1F>>CC(C)NC(=O)c1ccccc1Nc1nc(Nc2ccc(C=O)cc2)ncc1F -US06720320B2,6,COc1cccc2oc(-c3cc(C)no3)cc12>>Cc1cc(-c2cc3c(O)cccc3o2)on1 -US20140275129A1,2,Cc1ccc(C(=O)O)cc1.Nc1ccccc1>>Cc1ccc(C(=O)Nc2ccccc2)cc1 -US20090215743A1,6,COc1cccc(C2OC(CC(=O)N3CCC[C@@H]3C(=O)OC(C)(C)C)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC>>COc1cccc(C2OC(CC(=O)N3CCC[C@@H]3C(=O)O)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC -US20140088076A1,6,C[Si](C)(C)C#Cc1cc(F)ccc1Cl>>C#Cc1cc(F)ccc1Cl -US20100016586A1,1,COc1ccc(OC)c(Sc2nc3c(N)ncnc3[nH]2)c1.ClCCc1ccncc1>>COc1ccc(OC)c(Sc2nc3c(N)ncnc3n2CCc2ccncc2)c1 -US20120035214A1,1,CC(C)I.OCC(F)(F)COCc1ccc(Br)cc1>>CC(C)OCC(F)(F)COCc1ccc(Br)cc1 -US20090163489A1,3,CC(=O)Nc1cn2nc(Cl)ccc2n1.COc1cc(Br)cnc1OC>>COc1cc(-c2ccc3nc(NC(C)=O)cn3n2)cnc1OC -US20060257987A1,1,CCCc1c(OC(CCC)CCOS(C)(=O)=O)ccc2c(-c3ccccc3)noc12.CCOC(=O)C(C)(C)Oc1ccc(O)cc1>>CCCc1c(OC(CCC)CCOc2ccc(OC(C)(C)C(=O)OCC)cc2)ccc2c(-c3ccccc3)noc12 -US06528504B2,1,CS(=O)(=O)O[C@H]1CCN(CCc2ccc(Cl)cc2)C1.c1ccc2c(c1)COc1ccccc1N2>>Clc1ccc(CCN2CC[C@@H](N3c4ccccc4COc4ccccc43)C2)cc1 -US08524917B2,3,CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OS(=O)(=O)C(F)(F)F)cc2n1Cc1ccccc1.OB(O)c1ccncc1>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(-c3ccncc3)cc2n1Cc1ccccc1 -US04451463,2,Nc1ccn(CCCCO)n1.O=C(N=C=S)c1ccccc1>>O=C(NC(=S)Nc1ccn(CCCCO)n1)c1ccccc1 -US04997840,7,Cn1cc(OC(=O)c2ccccc2)c(=O)c2ccc(F)cc21>>Cn1cc(O)c(=O)c2ccc(F)cc21 -US20080004271A1,3,CCOC(=O)CC#N.O=Cc1cc2c(c(OCc3ccccc3)c1)CCO2>>CCOC(=O)C(C#N)=Cc1cc2c(c(OCc3ccccc3)c1)CCO2 -US20080076758A1,1,O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1.O=S(=O)(N1CCNCC1)C(F)(F)F>>O=S(=O)(N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1)C(F)(F)F -US20110313196A1,1,CC(C)(C)c1ccc(C=O)cc1.CCc1cc(CCN)ccc1Cl>>CCc1cc(CCNCc2ccc(C(C)(C)C)cc2)ccc1Cl -US07001895B2,3,COc1c(Br)cnn(-c2ccc(F)c(F)c2)c1=O.CSc1ccc(B(O)O)cc1C>>COc1c(-c2ccc(SC)c(C)c2)cnn(-c2ccc(F)c(F)c2)c1=O -US20080004271A1,1,BrCc1ccccc1.CCOC(=O)c1cc(O)c2c(c1)OCC2>>CCOC(=O)c1cc2c(c(OCc3ccccc3)c1)CCO2 -US20120302549A1,2,CC1(C)C[C@@]2(N=C(N)OCC2(F)F)c2cc(N)ccc2O1.N#Cc1ccc(C(=O)O)nc1>>CC1(C)C[C@@]2(N=C(N)OCC2(F)F)c2cc(NC(=O)c3ccc(C#N)cn3)ccc2O1 -US07709471B2,2,CN1CCC(N)CC1.Nc1ccc(C(=O)O)cn1>>CN1CCC(NC(=O)c2ccc(N)nc2)CC1 -US08569342B2,4,O=C(OCc1ccccc1)N1CC=CCC1.O=C(OO)c1cccc(Cl)c1>>O=C(OCc1ccccc1)N1CCC2OC2C1 -US20150182537A1,2,CN(CC(Cc1ccc(Cl)c(F)c1)C(=O)O)C(=O)OC(C)(C)C.Cn1nccc1Nc1nccc(-c2cc(F)nc(NN)c2)n1>>CN(CC(Cc1ccc(Cl)c(F)c1)C(=O)NNc1cc(-c2ccnc(Nc3ccnn3C)n2)cc(F)n1)C(=O)OC(C)(C)C -US20070060588A1,1,Nc1ccc(I)cc1.O=C1CN2CCC1CC2>>Ic1ccc(NC2CN3CCC2CC3)cc1 -US20050090559A1,6,COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2nccnc12)C(F)(F)F>>CC(C)(CC(O)(CNc1cccc2nccnc12)C(F)(F)F)c1cc(F)ccc1O -US04197110,8,O=C(OO)c1ccc([N+](=O)[O-])cc1>>O=C(O)c1ccc([N+](=O)[O-])cc1 -US20080312234A1,2,C=Cc1cc(CN)ccc1NS(C)(=O)=O.CC(C)(C)c1ccc(C=CC(=O)O)cn1>>C=Cc1cc(CNC(=O)C=Cc2ccc(C(C)(C)C)nc2)ccc1NS(C)(=O)=O -US20090137580A1,1,Cn1ccc2ncnc(Cl)c21.Nc1ccc(O)cc1>>Cn1ccc2ncnc(Oc3ccc(N)cc3)c21 -US20090163462A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(Oc2ccc(-c3ccccc3)cc2)cc1>>c1ccc(-c2ccc(Oc3ccc(OC[C@H]4CCCN4)cc3)cc2)cc1 -US20030176460A1,1,CC(C)(C)OC(=O)N1[C@@H](C=O)COC1(C)C.O=C(c1ccc(Cl)cc1)C1CCNCC1>>CC(C)(C)OC(=O)N1[C@@H](CN2CCC(C(=O)c3ccc(Cl)cc3)CC2)COC1(C)C -US06627651B1,2,Cc1ccc(-c2ccc3c(c2)CNCC3)cc1.O=C=Nc1ccc(CCl)cc1>>Cc1ccc(-c2ccc3c(c2)CN(C(=O)Nc2ccc(CCl)cc2)CC3)cc1 -US20130178478A1,1,CCOC(=O)c1nnc(Cl)cc1Cl.Cc1ccc(N)nc1C>>CCOC(=O)c1nnc(Cl)cc1Nc1ccc(C)c(C)n1 -US20140274703A1,6,COC(=O)c1nc(-c2ccc(I)c(F)c2C)cc(NC(C)=O)c1Cl>>COC(=O)c1nc(-c2ccc(I)c(F)c2C)cc(N)c1Cl -US05006556,1,BrCCCCCBr.Cc1ccc(CCO)cc1>>Cc1ccc(CCOCCCCCBr)cc1 -US04732901,3,CCCCCCCCCCCC#Cc1cnccc1C=O.CCOC(=O)CC(=O)OCC>>CCCCCCCCCCCC#Cc1cnccc1C=C(C(=O)OCC)C(=O)OCC -US20060287297A1,6,COC(=O)c1cccc2c(=O)c3ccccc3oc12>>O=C(O)c1cccc2c(=O)c3ccccc3oc12 -US05242914,2,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O.CNC>>CN(C)C(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C -US05495020,1,Cc1c(F)c([N+](=O)[O-])c(Cl)c(F)c1N1CCN(C)CC1.NC1CC1>>Cc1c(NC2CC2)c([N+](=O)[O-])c(Cl)c(F)c1N1CCN(C)CC1 -US08309546B2,2,CC(=O)OC(C)=O.Nc1ncc(-c2nc(N3CCOCC3)c3nc(N4CCNC5(CC5)C4)n(CC(F)(F)F)c3n2)cn1>>CC(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)CC12CC2 -US20150018363A1,2,CNc1cc(Br)ccc1[N+](=O)[O-].COCC(=O)Cl>>COCC(=O)N(C)c1cc(Br)ccc1[N+](=O)[O-] -US20040014968A1,2,CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1F.Nc1ccccn1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2ccccn2)cc1F -US04880809,2,CCCCOc1cc2ccc(C(=O)O)cc2cc1OCCCC.COc1cc(CN2CCNCC2)cc(OC)c1OC>>CCCCOc1cc2ccc(C(=O)N3CCN(Cc4cc(OC)c(OC)c(OC)c4)CC3)cc2cc1OCCCC -US07855211B2,1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(F)cn1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])nc2)CC1 -US04198418,1,ClCC1CC1.O=C1c2ccccc2Oc2ccccc2C12CCNCC2>>O=C1c2ccccc2Oc2ccccc2C12CCN(CC1CC1)CC2 -US04420487,4,CC(C)C(=O)O.Nc1cc(Cl)c(S(N)(=O)=O)cc1N>>CC(C)c1nc2cc(Cl)c(S(N)(=O)=O)cc2[nH]1 -US20070049632A1,1,Cn1[nH]c(=O)c2c1[C@]1(C)CC[C@H]2C1(C)C.Fc1cccc(CBr)c1>>Cn1c2c(c(=O)n1Cc1cccc(F)c1)[C@H]1CC[C@]2(C)C1(C)C -US20070129372A1,7,O=c1ccn2cc(C#Cc3ccc(F)cc3F)ccc2c1-c1c(F)cccc1F>>O=c1ccn2cc(/C=C\c3ccc(F)cc3F)ccc2c1-c1c(F)cccc1F -US05750782,1,COC(=O)c1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1.OCCNCCO>>COC(=O)c1cc([N+](=O)[O-])c(N(CCO)CCO)c([N+](=O)[O-])c1 -US06548684B2,3,C=CC(=O)OCCCC.FC(F)(F)c1ccc(Cl)cc1>>CCCCOC(=O)C=Cc1ccc(C(F)(F)F)cc1 -US08993756B2,3,CCOC(=O)c1cn(COCC[Si](C)(C)C)c2ncnc(Cl)c12.Nc1cccc(B(O)O)c1>>CCOC(=O)c1cn(COCC[Si](C)(C)C)c2ncnc(-c3cccc(N)c3)c12 -US20130005707A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NCc2ccc([N+](=O)[O-])cc21>>CC(C)(C)OC(=O)N1Cc2ccc([N+](=O)[O-])cc2C1=O -US08580399B2,3,Brc1cccc(Br)c1.CC1(C)OB(c2cccc(-c3cccc4c3sc3ccccc34)c2)OC1(C)C>>Brc1cccc(-c2cccc(-c3cccc4c3sc3ccccc34)c2)c1 -US08410139B2,1,C1COCCN1.CC(C)[C@@H](NC(=O)NCC(C)(C)OC(=O)OCCBr)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1>>CC(C)[C@@H](NC(=O)NCC(C)(C)OC(=O)OCCN1CCOCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 -US07163954B2,3,N#CCOc1ccc2cc(Br)ccc2c1Br.OB(O)c1cc2ccccc2s1>>N#CCOc1ccc2cc(-c3cc4ccccc4s3)ccc2c1Br -US20080188528A1,6,COC(=O)c1cccn(Cc2ccc3ccccc3c2)c1=O>>O=C(O)c1cccn(Cc2ccc3ccccc3c2)c1=O -US20090221555A1,1,CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl.COCCOC(=O)N1CCCOc2cc(N)ccc21>>CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)OCCCN3C(=O)OCCOC)ncc1Cl -US07429594B2,1,COc1ccc(CC(O)CN)cc1.Cn1c(Cl)nc(-c2ccncc2)c(-c2ccc3ccccc3c2)c1=O>>COc1ccc(CC(O)CNc2nc(-c3ccncc3)c(-c3ccc4ccccc4c3)c(=O)n2C)cc1 -US20080234199A1,1,CCCCC(=O)c1ccc(O)cc1.OCCOCCCl>>CCCCC(=O)c1ccc(OCCOCCO)cc1 -US04282239,2,CCCCNC(=O)NS(=O)(=O)c1ccc(CCN)cc1.O=C(O)N1Cc2ccccc2C1=O>>CCCCNC(=O)NS(=O)(=O)c1ccc(CCNC(=O)N2Cc3ccccc3C2=O)cc1 -US07786304B2,2,CN1CCN(C(=O)Cl)CC1.O=C1c2nccnc2C(O)N1c1ccc(Cl)cn1>>CN1CCN(C(=O)OC2c3nccnc3C(=O)N2c2ccc(Cl)cn2)CC1 -US05408009,1,O=Cc1ccc(O)cc1.OCCCCCCCl>>O=Cc1ccc(OCCCCCCO)cc1 -US04766246,1,CC(C)(C)OC(=O)NC1(C(=O)O)CC1.CC1CCC(C)C1O>>CC1CCC(C)C1OC(=O)C1(NC(=O)OC(C)(C)C)CC1 -US04528298,8,COc1ccc(-c2nc(Sc3ccccc3NC(C)=O)[nH]c2-c2ccc(OC)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nc(S(=O)c3ccccc3NC(C)=O)[nH]c2-c2ccc(OC)cc2)cc1 -US20130336921A1,2,Nc1nc(-c2cccc(C(F)(F)F)c2)n[nH]1.O=C(Cl)c1cc(Cl)ccc1[N+](=O)[O-]>>O=C(Nc1nc(-c2cccc(C(F)(F)F)c2)n[nH]1)c1cc(Cl)ccc1[N+](=O)[O-] -US08426437B2,2,CN1CCNCC1.O=C(O)c1c[nH]c2c(=O)[nH]c3ccc(S(=O)(=O)Cl)cc3c12>>CN1CCN(S(=O)(=O)c2ccc3[nH]c(=O)c4[nH]cc(C(=O)O)c4c3c2)CC1 -US07138425B2,3,COc1ccc(-c2nc3cc(Br)ccc3o2)cc1[N+](=O)[O-].COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc3oc(-c4ccc(OC)c([N+](=O)[O-])c4)nc3c2)cc1 -US20060063937A1,2,COc1ccc2[nH]c(C)c(C(C)(C)C(=O)O)c2c1.O=C(Cl)c1ccc(Cl)cc1>>COc1ccc2c(c1)c(C(C)(C)C(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1 -US04363816,2,Cc1cn(C)c2c1Nc1ccccc1NC2=O.O=C(O)CN1CCCC1>>Cc1cn(C)c2c1N(C(=O)CN1CCCC1)c1ccccc1NC2=O -US06897208B2,2,Cc1cc(N)c(N)cc1C.O=C(Cl)c1n[nH]cc1[N+](=O)[O-]>>Cc1cc(N)c(NC(=O)c2n[nH]cc2[N+](=O)[O-])cc1C -US20050037925A1,1,CC(C)(C)c1ccccc1O.COCCOCCl>>COCCOCOc1ccccc1C(C)(C)C -US06423870B1,6,CCOC(=O)CC1Cc2cccc3cccc1c23>>O=C(O)CC1Cc2cccc3cccc1c23 -US07595314B2,1,CS(=O)(=O)c1ccc(I)c(C(=O)N2CCN(c3ccc(C(F)(F)F)cc3)CC2)c1.NCC1CCCO1>>CS(=O)(=O)c1ccc(NCC2CCCO2)c(C(=O)N2CCN(c3ccc(C(F)(F)F)cc3)CC2)c1 -US05691330,3,O=C(Cl)CCCCl.O=C1NCCCc2ccsc21>>O=C(CCCCl)c1cc2c(s1)C(=O)NCCC2 -US20040236084A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncnc(NC4CCCC4)n3)nc2)CC1>>c1nc(Nc2ccc(N3CCNCC3)cn2)nc(NC2CCCC2)n1 -US07247633B2,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1cncc(Cl)n1>>CC(C)(C)OC(=O)N1CCN(c2cncc(Cl)n2)CC1 -US20040121965A1,2,C=CC[C@H](NC(=O)OC(C)(C)C)C(=O)O.CNOC>>C=CCC(NC(=O)OC(C)(C)C)C(=O)N(C)OC -US20110028447A1,6,COC(=O)c1nn(Cc2ccccc2)c2ccc(Br)cc12>>O=C(O)c1nn(Cc2ccccc2)c2ccc(Br)cc12 -US06051712,2,CC(C)(C)OC(=O)N1CCC(c2ccc(CCCO)cc2)C(OCc2ccc3ccccc3c2)C1.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)OCCCc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3OCc3ccc4ccccc4c3)cc2)c1 -US20040122001A1,1,CS(=O)(=O)OCCC1OCCc2cc(C(N)=O)ccc21.C[C@H]1CN(c2csc3cc(F)ccc23)CCN1>>C[C@H]1CN(c2csc3cc(F)ccc23)CCN1CCC1OCCc2cc(C(N)=O)ccc21 -US08586620B2,1,C1COCCN1.O=[N+]([O-])c1ccc2ccn(CCCCl)c2c1>>O=[N+]([O-])c1ccc2ccn(CCCN3CCOCC3)c2c1 -US06207828B1,3,CCOC(=O)CC(=O)C(F)(F)F.CN(C)C=O>>CCOC(=O)C(=CN(C)C)C(=O)C(F)(F)F -US20040122057A1,2,COC(C(=O)O)c1ccc(C(F)(F)F)cc1C(F)(F)F.N#Cc1ccc(CN)cc1>>COC(C(=O)NCc1ccc(C#N)cc1)c1ccc(C(F)(F)F)cc1C(F)(F)F -US06537948B1,1,COC(=O)C(C)Br.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3ncncc3O)c(Cl)cc2F)c1=O>>COC(=O)C(C)Oc1cncnc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl -US20150218124A1,3,CC1(C)OB(Cc2ccc(COC3CCCCO3)cc2)OC1(C)C.CS(=O)(=O)Oc1cc(C#N)c(Br)c(C#N)c1OS(C)(=O)=O>>CS(=O)(=O)Oc1cc(C#N)c(Cc2ccc(COC3CCCCO3)cc2)c(C#N)c1OS(C)(=O)=O -US06812231B2,6,CC(C)(C)OC(=O)NCCOc1cc(C#N)ccc1OCc1ccccc1>>N#Cc1ccc(OCc2ccccc2)c(OCCN)c1 -US08293902B2,1,CC(=O)N1CCN(CCCO)CC1.COc1cc2c(Cl)ncnc2cc1O>>COc1cc2c(Cl)ncnc2cc1OCCCN1CCN(C(C)=O)CC1 -US05621113,7,Cc1csc(C(=O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1C>>Cc1csc(C(O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1C -US20150031685A1,6,CCOC(=O)Cc1ccc2sc(=O)[nH]c2c1>>O=C(O)Cc1ccc2sc(=O)[nH]c2c1 -US20100331306A1,1,CS(=O)(=O)OCc1nc2c(F)cccc2cc1-c1ccccc1S(C)(=O)=O.[N-]=[N+]=[N-]>>CS(=O)(=O)c1ccccc1-c1cc2cccc(F)c2nc1CN=[N+]=[N-] -US20060116368A1,2,Nc1cccnn1.O=C(O)C1CCN(c2cccs2)CC1>>O=C(Nc1cccnn1)C1CCN(c2cccs2)CC1 -US06645997B2,1,CCOC(=O)C1CCc2ccc(O)cc2O1.OCCBr>>CCOC(=O)C1CCc2ccc(OCCBr)cc2O1 -US20130184254A1,3,Nc1ncncc1Br.OB(O)c1ccnc2c1cnn2-c1ccc(F)cc1>>Nc1ncncc1-c1ccnc2c1cnn2-c1ccc(F)cc1 -US20120214782A1,1,CCNC(=O)C(C)c1ccc(C#Cc2cnc(Cl)nc2)cc1.OCCF>>CCNC(=O)C(C)c1ccc(C#Cc2cnc(OCCF)nc2)cc1 -US08492437B2,6,CCOC(=O)Cc1ccc(Oc2ccc(C(=O)NCCc3ccc(Cl)cc3)cc2)c(Br)c1>>O=C(O)Cc1ccc(Oc2ccc(C(=O)NCCc3ccc(Cl)cc3)cc2)c(Br)c1 -US20140128392A1,7,Nc1cc(O)c(C(=O)O)cc1[N+](=O)[O-]>>Nc1cc(O)c(C(=O)O)cc1N -US04529732,1,C=CCBr.CCCCCCC(C)(C)c1ccc([C@H]2C[C@@H](O)CCN2)c(OCc2ccccc2)c1>>C=CCN1CC[C@H](O)C[C@@H]1c1ccc(C(C)(C)CCCCCC)cc1OCc1ccccc1 -US05783591,1,CC(C)Br.COc1ccc(C2(C)CNC(=O)O2)cc1OCC1CC1>>COc1ccc(C2(C)CN(C(C)C)C(=O)O2)cc1OCC1CC1 -US07414036B2,6,CC(=O)c1cccc(CO[Si](C)(C)C(C)(C)C)n1>>CC(=O)c1cccc(CO)n1 -US08546376B2,3,C#Cc1ccccc1.CC(C)(C)OC(=O)NC1(c2ccc(Br)cc2)CCC1>>CC(C)(C)OC(=O)NC1(c2ccc(C#Cc3ccccc3)cc2)CCC1 -US05795986,1,CS(=O)(=O)OCCn1c2ccccc2c2c(N3CCCC3)nc(N3CCCC3)nc21.c1c[nH]cn1>>c1ccc2c(c1)c1c(N3CCCC3)nc(N3CCCC3)nc1n2CCn1ccnc1 -US20140031351A1,1,CI.CS(=O)(=O)Nc1ccc(Br)cc1[N+](=O)[O-]>>CN(c1ccc(Br)cc1[N+](=O)[O-])S(C)(=O)=O -US07947714B2,2,CCS(=O)(=O)N1CCC(CN)(CC(C)C)CC1.O=C(O)c1ccc(C(F)(F)F)cc1Cl>>CCS(=O)(=O)N1CCC(CNC(=O)c2ccc(C(F)(F)F)cc2Cl)(CC(C)C)CC1 -US07582651B2,3,CCOC(=O)CP(=O)(OCC)OCC.Cc1cc(C)c2c(C#N)c(C=O)n([C@H]3CCCc4ccccc43)c2n1>>CCOC(=O)/C=C/c1c(C#N)c2c(C)cc(C)nc2n1[C@H]1CCCc2ccccc21 -US20120122843A1,1,CNC(C)C(O)c1nc(C)cs1.Clc1ccc(CBr)c(Cl)n1>>Cc1csc(C(O)C(C)N(C)Cc2ccc(Cl)nc2Cl)n1 -US20070249688A1,1,C1COCCN1.CC(C)CC(Oc1ccc(-c2ccc(C(C)C)cc2)c(C=O)c1)c1ccc(C(=O)NCCC(=O)O)cc1>>CC(C)CC(Oc1ccc(-c2ccc(C(C)C)cc2)c(CN2CCOCC2)c1)c1ccc(C(=O)NCCC(=O)O)cc1 -US20100317864A1,6,CCOC(=O)C1CC(Br)=NN1c1ncccc1Cl>>O=C(O)C1CC(Br)=NN1c1ncccc1Cl -US20030191110A1,1,CC(C)CBr.O=C(C1CCCCN1)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1>>CC(C)CN1CCCC[C@H]1C(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US04093812,1,CI.N#Cc1c[nH]nc1-c1ccc([N+](=O)[O-])o1>>Cn1cc(C#N)c(-c2ccc([N+](=O)[O-])o2)n1 -US20060247320A1,7,[N-]=[N+]=NCC(=O)c1ccccn1>>[N-]=[N+]=NC[C@H](O)c1ccccn1 -US05616711,2,NC(=S)CCc1ccco1.O=C(Cl)c1ccccc1>>O=C(NC(=S)CCc1ccco1)c1ccccc1 -US20140275079A1,6,Cc1[nH]c(-c2ccccc2NCC2CCN(C(=O)OC(C)(C)C)CC2)cc1C(N)=O>>Cc1[nH]c(-c2ccccc2NCC2CCNCC2)cc1C(N)=O -US20120214991A1,2,CS(=O)(=O)Cl.O=C1C(c2cccnc2)=C(c2cc(F)cc(F)c2)c2ccc(OCCCN3CCNCC3)cc21>>CS(=O)(=O)N1CCN(CCCOc2ccc3c(c2)C(=O)C(c2cccnc2)=C3c2cc(F)cc(F)c2)CC1 -US08445487B2,1,CC(C)(O)c1nc2c(N3CCOCC3)nc(Cl)nc2[nH]1.CCCCBr>>CCCCn1c(C(C)(C)O)nc2c(N3CCOCC3)nc(Cl)nc21 -US08044206B2,3,CC(C)(C)OC(=O)N1CCC(C=O)CC1.Cc1cccc(C)c1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1cccc(C)c1/C=C/C1CCN(C(=O)OC(C)(C)C)CC1 -US08044206B2,3,CC(C)(C)OC(=O)N1CCC(C=O)CC1.Cc1cccc(C)c1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1cccc(C)c1/C=C\C1CCN(C(=O)OC(C)(C)C)CC1 -US20140142085A1,2,N[C@@H](Cc1cc(F)cc(F)c1)c1ncncc1-c1cnc2[nH]ccc2c1.O=C(O)Cn1nc(C(F)F)c2c1C1CC1CC2>>O=C(Cn1nc(C(F)F)c2c1C1CC1CC2)NC(Cc1cc(F)cc(F)c1)c1ncncc1-c1cnc2[nH]ccc2c1 -US20050065140A1,9,COc1ccc(Br)c(CC2CCN(CC(O)CN=[N+]=[N-])CC2)c1>>COc1ccc(Br)c(CC2CCN(CC(O)CN)CC2)c1 -US08106221B2,3,CC1(C)COC(c2ccc(F)cc2Br)=N1.CON(C)C(=O)CCN(C)C(=O)OC(C)(C)C>>CN(CCC(=O)c1cc(F)ccc1C1=NC(C)(C)CO1)C(=O)OC(C)(C)C -US20080255085A1,3,CN1CCN(C(=O)c2ccc(-c3nc4c(Cl)ccnc4[nH]3)cc2)CC1.COc1ccc(B(O)O)c(C)c1>>COc1ccc(-c2ccnc3[nH]c(-c4ccc(C(=O)N5CCN(C)CC5)cc4)nc23)c(C)c1 -US20120010235A1,1,C=O.COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1OC>>COC(=O)c1ccc(NC(=O)[C@H]2[C@H](c3cccc(Cl)c3F)[C@@](C#N)(c3ccc(Cl)cc3F)[C@H](CC(C)(C)C)N2C)cc1OC -US20060106048A1,1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccccc1)=NC(C)(CNC(=O)CCl)C2.CNC>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccccc1)=NC(C)(CNC(=O)CN(C)C)C2 -US20060106048A1,6,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(/C=C/C(=O)OC)c(C)c1)=NC(C)(C)C2>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(/C=C/C(=O)O)c(C)c1)=NC(C)(C)C2 -US04497738,6,CC(=O)N1CSC2C(NC(=O)COc3ccccc3)C(=O)N2C1C(=O)OCc1ccccc1>>CC(=O)N1CSC2C(NC(=O)COc3ccccc3)C(=O)N2C1C(=O)O -US05112848,3,CN(C)C=O.c1ccc(-c2ccco2)cc1>>O=Cc1ccc(-c2ccccc2)o1 -US06841556B2,2,COc1ccc(-c2[nH]nc(C)c2N)cc1.O=C(Cl)c1ccccc1>>COc1ccc(-c2[nH]nc(C)c2NC(=O)c2ccccc2)cc1 -US20100324140A1,3,Cc1cc([N+](=O)[O-])cnc1Cl.OB(O)c1ccc(C(F)(F)F)cc1>>Cc1cc([N+](=O)[O-])cnc1-c1ccc(C(F)(F)F)cc1 -US05512207,3,CCCCCCCCOc1ccc(B(O)O)cn1.Clc1ccc(-c2ccc(OCc3ccccc3)cc2)nn1>>CCCCCCCCOc1ccc(-c2ccc(-c3ccc(OCc4ccccc4)cc3)nn2)cn1 -US07709471B2,7,CCOC(=O)C1(C#N)CC1>>CCOC(=O)C1(CN)CC1 -US20120121540A1,2,CN(C)CCN.O=C(O)C1CN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)CC1c1ccccc1>>CN(C)CCNC(=O)C1CN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)CC1c1ccccc1 -US07355069B2,1,CCN(Cc1ccccc1F)C(=O)Cc1ccc(O)cc1.COC(=O)c1ccccc1CBr>>CCN(Cc1ccccc1F)C(=O)Cc1ccc(OCc2ccccc2C(=O)OC)cc1 -US04544764,6,COc1cccc2c1CC(CC(=O)O)C1(C2)OCCO1>>COc1cccc2c1CC(CC(=O)O)C(=O)C2 -US20140038937A1,2,C1COCCN1.O=C(O)c1cc([C@H]2CCCN2c2cccc(F)c2)c2oc(N3CCOCC3)cc(=O)c2c1>>O=C(c1cc([C@H]2CCCN2c2cccc(F)c2)c2oc(N3CCOCC3)cc(=O)c2c1)N1CCOCC1 -US20120088795A1,1,CC(=O)/N=c1\ccccn1-c1ccc(I)cc1.O=C(NCc1c[nH]cn1)c1ccc(Cl)s1>>CC(=O)/N=c1\ccccn1-c1ccc(-n2cnc(CNC(=O)c3ccc(Cl)s3)c2)cc1 -US20110294808A1,1,COC(=O)c1cc(Br)cc2[nH]ncc12.Fc1ccc(I)cc1>>COC(=O)c1cc(Br)cc2c1cnn2-c1ccc(F)cc1 -US20080058521A1,3,Cc1ccc(Br)cc1C=O.OB(O)c1ccncc1>>Cc1ccc(-c2ccncc2)cc1C=O -US07105515B2,1,CCI.CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12>>CCN(CC)CCc1c[nH]c2ccc(N(CC)S(=O)(=O)c3ccc4ccccc4c3)cc12 -US20130005751A1,1,CC1Cc2c(ncnc2Oc2ccc3c(ccn3C(=O)Nc3cccc(C(F)(F)F)c3)c2)CN1.COC(=O)CBr>>COC(=O)CN1Cc2ncnc(Oc3ccc4c(ccn4C(=O)Nc4cccc(C(F)(F)F)c4)c3)c2CC1C -US20100256182A1,2,CN.COc1cc2c(cc1OC)C(CCc1ccc(C(F)(F)F)nc1)N(C(C(=O)O)c1ccccc1)CC2>>CNC(=O)C(c1ccccc1)N1CCc2cc(OC)c(OC)cc2C1CCc1ccc(C(F)(F)F)nc1 -US08273773B2,3,CC(C)(C)c1cc(Br)c(O)c(C=O)c1.COc1ncccc1B(O)O>>COc1ncccc1-c1cc(C(C)(C)C)cc(C=O)c1O -US06177443B1,2,CN(C)c1ccc(C(=O)O)cc1.FC(F)(F)c1ccc(C2NCCc3sccc32)cc1>>CN(C)c1ccc(C(=O)N2CCc3sccc3C2c2ccc(C(F)(F)F)cc2)cc1 -US20110059936A1,3,CC1(C)OB(c2cnc(N)c(-c3nnnn3-c3cccc(F)c3F)c2)OC1(C)C.CCOC(=O)N1CCc2cc(Br)sc2CC1>>CCOC(=O)N1CCc2cc(-c3cnc(N)c(-c4nnnn4-c4cccc(F)c4F)c3)sc2CC1 -US20080004273A1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.O=[N+]([O-])c1ccc(O)c(F)c1>>COc1cc2ncc(C#N)c(Oc3ccc([N+](=O)[O-])cc3F)c2cc1OC -US04189484,2,C1CNCCN1.O=C(Cl)C=Cc1ccco1>>O=C(C=Cc1ccco1)N1CCNCC1 -US05877196,6,CC(=O)c1ccc(OCCCCN2C(=O)c3ccccc3C2=O)cc1>>CC(=O)c1ccc(OCCCCN)cc1 -US07691850B2,2,COc1ccc2ncc(F)c(CCN3CC[C@H](CN)C3)c2n1.O=C1CSc2ccc(S(=O)(=O)Cl)cc2N1>>COc1ccc2ncc(F)c(CCN3CC[C@H](CNS(=O)(=O)c4ccc5c(c4)NC(=O)CS5)C3)c2n1 -US20090247507A1,1,Nc1ncc(Br)c(Cl)c1[N+](=O)[O-].c1ccc(CC2CCNCC2)cc1>>Nc1ncc(Br)c(N2CCC(Cc3ccccc3)CC2)c1[N+](=O)[O-] -US20100113418A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C(CBr)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCC(O)(CC(=O)OCc2ccccc2)CC1 -US20060106019A1,3,CN(c1ccccc1)c1ncnc2c(I)cnn12.OB(O)c1ccccc1>>CN(c1ccccc1)c1ncnc2c(-c3ccccc3)cnn12 -US08557828B2,2,C#CC1(N)CCCCC1.O=S(=O)(Cl)c1cccc(Cl)c1>>C#CC1(NS(=O)(=O)c2cccc(Cl)c2)CCCCC1 -US20110166137A1,6,CNc1nccc(-c2cc(NCCCN3C(=O)c4ccccc4C3=O)c3cc(OC)ccc3c2)n1>>CNc1nccc(-c2cc(NCCCN)c3cc(OC)ccc3c2)n1 -US20110021501A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(O)cc2)CC1.CCN(CC)CCCl>>CCN(CC)CCOc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20070043024A1,7,O=C(CN1CCc2ccccc2C1)NCCC(c1ccccc1)c1ccccc1>>c1ccc(C(CCNCCN2CCc3ccccc3C2)c2ccccc2)cc1 -US08461329B2,7,CCOC(=O)CC(C#N)c1cccc(OC)c1>>CCOC(=O)CC(CN)c1cccc(OC)c1 -US06399614B1,7,COc1cc([N+](=O)[O-])ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2OC(F)(F)F)CC1>>COc1cc(N)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2OC(F)(F)F)CC1 -US04160862,2,COc1ccc2[nH]c(C)c(CCN3CCCCC3CC3CCCCC3)c2c1.O=C(Cl)c1ccc(Cl)cc1Br>>COc1ccc2c(c1)c(CCN1CCCCC1CC1CCCCC1)c(C)n2C(=O)c1ccc(Cl)cc1Br -US05981595,2,CC(C)c1cccc(C(C)C)c1N=C=O.CCCCCCCCCCCCCCS(N)(=O)=O>>CCCCCCCCCCCCCCS(=O)(=O)NC(=O)Nc1c(C(C)C)cccc1C(C)C -US20040087798A1,1,NCc1cccnc1.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(NCc2cccnc2)nc1 -US08119627B2,6,CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccccc2Oc2ccc(C(F)(F)F)cc2)CC1>>O=C(Nc1ccccc1Oc1ccc(C(F)(F)F)cc1)C1CCNCC1 -US20100280268A1,7,CCCNc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1[N+](=O)[O-]>>CCCNc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1N -US08765730B2,9,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(NS(=O)(=O)C2CC2)cc1.NO>>Cc1cc(Cl)ccc1C(C/C(=N\O)c1ccc(=O)n(C)c1)c1ccc(NS(=O)(=O)C2CC2)cc1 -US08173658B2,1,CCBr.c1ccc(-c2ccc(N3CC4CCCC(C3)N4)nn2)cc1>>CCN1C2CCCC1CN(c1ccc(-c3ccccc3)nn1)C2 -US20150018547A1,2,CS(=O)(=O)Cl.NC(=O)Cc1csc2cc(OCc3ccc(Cl)cc3Cl)ccc12>>CS(=O)(=O)NC(=O)Cc1csc2cc(OCc3ccc(Cl)cc3Cl)ccc12 -US20050250784A1,6,COC(=O)c1cnc(N2CCN(C(=O)Cc3ccccc3)CC2)s1>>O=C(O)c1cnc(N2CCN(C(=O)Cc3ccccc3)CC2)s1 -US20130253186A1,1,Clc1ccc2ccccc2n1.c1cnc(OC2CNC2)c(C2CCOCC2)c1>>c1cnc(OC2CN(c3ccc4ccccc4n3)C2)c(C2CCOCC2)c1 -US06194406B1,1,CCOCCn1c(N2CCCNCC2)nc2ccccc21.COc1ccc(OC)c(C(=O)N2CCC(CCOS(C)(=O)=O)(c3ccccc3)C2)c1>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(OC)ccc4OC)C3)CC2)nc2ccccc21 -US09070885B2,3,O=S(=O)(Oc1ccc2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cc2c1)C(F)(F)F.OB(O)c1ccc2c3ccccc3c3ccccc3c2c1>>c1ccc2c(-c3c4ccccc4c(-c4ccc5ccc(-c6ccc7c8ccccc8c8ccccc8c7c6)cc5c4)c4ccccc34)cccc2c1 -US08053435B2,6,O=C(CCCC/C=C(\COc1cccc2ccccc12)C(=O)NCCCn1ccnc1)NOC1CCCCO1>>O=C(CCCC/C=C(\COc1cccc2ccccc12)C(=O)NCCCn1ccnc1)NO -US05472964,2,CS(=O)(=O)Cl.Cc1nc2ccc(CO)nc2s1>>Cc1nc2ccc(COS(C)(=O)=O)nc2s1 -US06593324B2,4,CCOC(=O)C(C(C)=O)C(C)C.Nc1ccccc1>>Cc1nc2ccccc2c(O)c1C(C)C -US20070117760A1,6,CCOC(=O)c1cc([N+](=O)[O-])cn1C1CCCC1>>O=C(O)c1cc([N+](=O)[O-])cn1C1CCCC1 -US20080161303A1,3,Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1.Nc1nnc2cc(Br)ccn12>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccn2c(N)nnc2c1 -US20070124152A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCO)c1=O.C[C@@H](O)CN>>C[C@@H](O)CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCO)c1=O -US20040132727A1,7,COc1cc2nccc(Oc3ccc(NC(=O)COc4ccccc4)cc3C)c2cc1OC>>COc1cc2nccc(Oc3ccc(NCCOc4ccccc4)cc3C)c2cc1OC -US08598174B2,6,CCOC(=O)c1cc2c(s1)CC(C)(C)C2=O>>CC1(C)Cc2sc(C(=O)O)cc2C1=O -US20070072885A1,8,Cc1cc([N+](=O)[O-])ccc1Oc1ccc(CO)nc1.O=C(OO)c1cccc(Cl)c1>>Cc1cc([N+](=O)[O-])ccc1Oc1ccc(CO)[n+]([O-])c1 -US20110090450A1,3,CCCCCC1CCC(c2cccc(F)c2F)(C2CCC(=O)CC2)CC1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCC1CCC(c2cccc(F)c2F)(C2CCC(=COC)CC2)CC1 -US20070249710A1,2,CC1(C)CCC(C)(C)c2cc(C(=O)COc3ccc(C(=O)O)c(O)c3)ccc21.CCO>>CCOC(=O)c1ccc(OCC(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1O -US20150038528A1,1,CCOC(=O)CNCc1ccc(OC)cc1OC.CCOC(=O)c1ccc(Br)cc1CBr>>CCOC(=O)CN(Cc1ccc(OC)cc1OC)Cc1cc(Br)ccc1C(=O)OCC -US20110076291A1,2,Fc1ccc(C2CCNCC2)c(F)c1.O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2>>O=C(c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2)N1CCC(c2ccc(F)cc2F)CC1 -US20140288123A1,2,Cc1cc(C)c(CN)c(O)n1.O=C(O)c1ccc(CNc2ccccc2)cc1>>Cc1cc(C)c(CNC(=O)c2ccc(CNc3ccccc3)cc2)c(O)n1 -US05703098,1,CCBr.COc1ccc(C(CCO)N2Cc3ccccc3C2=O)cc1OC>>CCOCCC(c1ccc(OC)c(OC)c1)N1Cc2ccccc2C1=O -US20080207616A1,2,CC(C)(C#N)c1cccc(C(=O)Nc2ccc(F)c(N)c2)c1.O=C(O)c1ccc2nccnc2c1>>CC(C)(C#N)c1cccc(C(=O)Nc2ccc(F)c(NC(=O)c3ccc4nccnc4c3)c2)c1 -US20100210630A1,6,COC(=O)CCN1CCCN(Cc2ccc(OCc3ccccc3)cc2)CC1>>O=C(O)CCN1CCCN(Cc2ccc(OCc3ccccc3)cc2)CC1 -US06545150B2,1,COC(=O)CBr.COC(=O)c1ccccc1S(=O)(=O)Nc1ccccc1C(F)(F)F>>COC(=O)CN(c1ccccc1C(F)(F)F)S(=O)(=O)c1ccccc1C(=O)OC -US06489485B2,2,CN(C)S(=O)(=O)Cl.Nc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1>>CN(C)S(=O)(=O)Nc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1 -US20100009950A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC(O)CO>>CC(C)(C)OC(=O)NCC(O)CO -US20100048610A1,9,CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1cncc(Br)c1.[C-]#N>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1cncc(C#N)c1 -US07517880B2,2,COc1cc2ccccc2cc1N.O=C=Nc1cccc2ccccc12>>COc1cc2ccccc2cc1NC(=O)Nc1cccc2ccccc12 -US06770617B2,2,CCCCCCCC/C=C\CCCCCCCC(=O)O.CN(C)CCO>>CCCCCCCC/C=C\CCCCCCCC(=O)OCCN(C)C -US20090036422A1,6,COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)C(NC(=O)OC(C)(C)C)c2ccccc2OC)cc1OC>>COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)C(N)c2ccccc2OC)cc1OC -US20060234927A1,5,C1CNCCN1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCNCC1 -US20070088044A1,1,COc1cc(O)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1.OC1CCSC1>>COc1cc(OC2CCSC2)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1 -US07595327B2,6,Cc1cc(COc2ccc(S(=O)(=O)N[C@@H]3CCN(C(=O)OC(C)(C)C)C[C@]3(O)C(=O)NOC(C)(C)C)cc2)c2ccccc2n1>>Cc1cc(COc2ccc(S(=O)(=O)N[C@@H]3CCNC[C@]3(O)C(=O)NOC(C)(C)C)cc2)c2ccccc2n1 -US20120077812A1,3,CC(C)OC(=O)N1CCC(COc2ccc(Br)nc2F)CC1.CS(=O)(=O)c1ccc(B(O)O)cc1>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2F)CC1 -US06482827B1,6,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CC(=O)O)C(=O)O -US08957070B2,2,CCOC(=O)c1cc2cccc(N)c2[nH]1.O=C(O)c1cc(OCc2ccccc2F)cc(OCc2ccccc2F)c1>>CCOC(=O)c1cc2cccc(NC(=O)c3cc(OCc4ccccc4F)cc(OCc4ccccc4F)c3)c2[nH]1 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.NCc1ccccc1>>CC#CCOc1cc(NCc2ccccc2)ncn1 -US06521620B1,4,NC=O.Nc1ccncc1C(=O)O>>O=c1[nH]cnc2ccncc12 -US20130216498A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(NCCN3CCOCC3)nc(-c3cnc4ccc(F)cn34)n2)C1>>Fc1ccc2ncc(-c3nc(NCCN4CCOCC4)cc(N[C@@H]4CCCNC4)n3)n2c1 -US20050070521A1,1,C=CC(=O)OC(C)(C)C.OCCc1ccc2sccc2c1>>CC(C)(C)OC(=O)CCOCCc1ccc2sccc2c1 -US20110136763A1,1,C1=COCCC1.CCc1cc(O)cc(O)c1C=O>>CCc1cc(OC2CCCCO2)cc(O)c1C=O -US04315858,2,CC(=O)O.Nc1ccc(-c2ccc(C(=O)O)c(=O)[nH]2)cc1>>CC(=O)Nc1ccc(-c2ccc(C(=O)O)c(=O)[nH]2)cc1 -US05202324,2,CC(C)(CO)CS(N)(=O)=O.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC(C)(C)CS(N)(=O)=O)cc1 -US20020042427A1,3,CN(C)C=O.O=C1OCCc2c[nH]cc21>>O=Cc1[nH]cc2c1CCOC2=O -US20140213578A1,2,NCCCN1c2ccc(Cl)cc2CCc2cc(Cl)ccc21.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=S(=O)(NCCCN1c2ccc(Cl)cc2CCc2cc(Cl)ccc21)c1ccc(Cl)cc1 -US05780607,2,CC(C)C(=O)OC(=O)C(C)C.Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(=O)OCC2c3ccccc3-c3ccccc32)c(=O)[nH]1>>CC(C)C(=O)Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(=O)OCC2c3ccccc3-c3ccccc32)c(=O)[nH]1 -US20120316147A1,2,Cc1nc(C(C)(N)CC2CC2)no1.O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1>>Cc1nc(C(C)(CC2CC2)NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)no1 -US08952169B2,2,NS(=O)(=O)N1CCC1.O=C(O)c1cc(C2CC2)c(OCC23CC4CC(C2)CC(OC(=O)C(F)(F)F)(C4)C3)cc1F>>O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(C2)CC(OC(=O)C(F)(F)F)(C4)C3)cc1F -US20100063119A1,6,CCCc1cc(C(=O)OC)ccc1OCc1ccccc1>>CCCc1cc(C(=O)O)ccc1OCc1ccccc1 -US20090215822A1,2,O=C(Cl)c1ccc(F)cc1.c1cc(-c2nc(C3CCCNC3)no2)ccn1>>O=C(c1ccc(F)cc1)N1CCCC(c2noc(-c3ccncc3)n2)C1 -US20090203705A1,1,Nc1ccc(Cl)nn1.OC1CCCC1>>Nc1ccc(OC2CCCC2)nn1 -US04921855,2,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O.CC(C)CC[C@H](O)[C@@H](N)CC1CCCCC1>>CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)OC(C)(C)C -US04024273,1,CCNCC.O=C(c1ccc(OCCCBr)cc1)c1oc2ccccc2c1-c1ccccc1>>CCN(CC)CCCOc1ccc(C(=O)c2oc3ccccc3c2-c2ccccc2)cc1 -US04333940,1,CCCCCCCCCCCCCCCCBr.CCOC(=O)c1ccc(N)c(F)c1>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)OCC)cc1F -US20150232472A1,1,Cc1nc2ccc(Cl)nn2c1C.Cn1nc(N2CCCC2)nc1CS>>Cc1nc2ccc(SCc3nc(N4CCCC4)nn3C)nn2c1C -US20140088053A1,7,C[C@]12CC[C@@H]3c4ccc(C(=O)O)cc4CC[C@H]3[C@@H]1C/C(=C\c1cccc(C(N)=O)c1)C2=O>>C[C@]12CC[C@@H]3c4ccc(C(=O)O)cc4CC[C@H]3[C@@H]1C/C(=C\c1cccc(C(N)=O)c1)[C@@H]2O -US20090143409A1,3,Nc1ncc(Br)nc1Br.OB(O)c1ccc(Cl)cc1>>Nc1ncc(Br)nc1-c1ccc(Cl)cc1 -US20100280268A1,2,COC(=O)c1cc(Oc2ccc(N)c(Cc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(Cc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1 -US20150080549A1,1,CC(C)(C)OC(=O)N[C@@H](CSSC(C)(C)C)C(=O)O.N#CCBr>>CC(C)(C)OC(=O)N[C@@H](CSSC(C)(C)C)C(=O)OCC#N -US20060270688A1,2,Cc1cc(Cl)ccc1OCC(=O)O.c1ccc2c(c1)CCCN2>>Cc1cc(Cl)ccc1OCC(=O)N1CCCc2ccccc21 -US20110105567A1,2,CCCCc1c(C(=O)O)c(C(C)C)n(Cc2ccccc2)c1CC.NCc1ccc(F)c(F)c1>>CCCCc1c(C(=O)NCc2ccc(F)c(F)c2)c(C(C)C)n(Cc2ccccc2)c1CC -US05036086,2,COCC(=O)Cl.Nc1nc2ccc(F)cc2s1>>COCC(=O)Nc1nc2ccc(F)cc2s1 -US20110105535A1,2,CC(=O)OC(C)=O.Cc1cc(-c2sc(N)nc2C)nc(N(C)CCN(C)C)n1>>CC(=O)Nc1nc(C)c(-c2cc(C)nc(N(C)CCN(C)C)n2)s1 -US07094779B2,1,O=C(CBr)c1ccccc1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCNC[C@H]1Cc1c[nH]c2ccccc12>>O=C(CN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2c[nH]c3ccccc23)C1)c1ccccc1 -US08697725B2,6,COC(=O)Cn1cc(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)nn1>>CC(=O)N1c2ccc(-c3cn(CC(=O)O)nn3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C -US20130345181A1,1,Brc1ccccn1.Cn1cc(-c2cc3cnc(Br)cc3[nH]2)cn1>>Cn1cc(-c2cc3cnc(Br)cc3n2-c2ccccn2)cn1 -US20120316147A1,2,CC(C)(N)c1ncco1.O=C(O)c1ccc(Cl)c(-c2cccc(Cl)c2)n1>>CC(C)(NC(=O)c1ccc(Cl)c(-c2cccc(Cl)c2)n1)c1ncco1 -US20060041123A1,6,COc1ccc2ncc(Cl)c(CCN3CC[C@H](NC(=O)OC(C)(C)C)[C@H](O)C3)c2c1>>COc1ccc2ncc(Cl)c(CCN3CC[C@H](N)[C@H](O)C3)c2c1 -US04758559,7,COC(=O)c1ccccc1-n1cccc1>>OCc1ccccc1-n1cccc1 -US20110178001A1,6,CCC(=O)OCOC(=O)NCC(=O)OCC(OC)OC>>CCC(=O)OCOC(=O)NCC(=O)OCC=O -US20040204586A1,2,CCOC(=O)c1c(O)c2cc(C)ccc2n(C)c1=O.NC1CCCCC1>>Cc1ccc2c(c1)c(O)c(C(=O)NC1CCCCC1)c(=O)n2C -US20150190335A1,7,O=C(Oc1cccc([N+](=O)[O-])c1)c1ccccc1>>Nc1cccc(OC(=O)c2ccccc2)c1 -US20090136472A1,1,CI.Cc1ccc(N=C2NC(=O)C(Cc3cccc(C(F)(F)F)c3)S2)cc1>>Cc1ccc(N=C2SC(Cc3cccc(C(F)(F)F)c3)C(=O)N2C)cc1 -US04139540,1,COc1ccc(CCC2COC(CBr)(c3ccc(Cl)cc3Cl)O2)cc1.c1c[nH]cn1>>COc1ccc(CCC2COC(Cn3ccnc3)(c3ccc(Cl)cc3Cl)O2)cc1 -US20080318937A1,6,CC(C)(C)OC(=O)N1CCC(N2c3ccccc3Oc3cc(-c4cccnc4)ccc32)CC1>>c1cncc(-c2ccc3c(c2)Oc2ccccc2N3C2CCNCC2)c1 -US20120214803A1,3,Fc1ccc([Mg+])cc1F.O=Cc1ccc2cccnc2c1[N+](=O)[O-]>>O=[N+]([O-])c1c(C(O)c2ccc(F)c(F)c2)ccc2cccnc12 -US20070208005A1,10,Cc1ccc(N2CCCC2=O)nc1.O=C1CCC(=O)N1Br>>O=C1CCCN1c1ccc(CBr)cn1 -US08309734B2,3,C#Cc1ccc(C(=O)OC)c(Cl)c1.O=C(c1cccnc1Oc1cc(Cl)c(Br)cc1Cl)N1CCN(C2CC2)c2ccccc21>>COC(=O)c1ccc(C#Cc2cc(Cl)c(Oc3ncccc3C(=O)N3CCN(C4CC4)c4ccccc43)cc2Cl)cc1Cl -US20110009394A1,1,NC1CCN(CC2CCn3c(=O)cnc4ccc(=O)n2c43)CC1.O=Cc1ccc2c(n1)NC(=O)CS2>>O=C1CSc2ccc(CNC3CCN(CC4CCn5c(=O)cnc6ccc(=O)n4c65)CC3)nc2N1 -US20060111416A1,4,COc1ccc(N)c(N)c1.O=C(O)CO>>COc1ccc2[nH]c(CO)nc2c1 -US20110136763A1,6,Cc1cc(OC2CCCCO2)cc2c1C(CC(=O)OC(C)(C)C)OB2O>>Cc1cc(O)cc2c1C(CC(=O)OC(C)(C)C)OB2O -US08304371B2,2,CS(=O)(=O)Cl.OCc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Br>>CS(=O)(=O)OCc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Br -US20120264733A1,4,CC(=O)NNC(=O)CCn1c(C(=O)N(CC(C)C)[C@H]2C[C@@H](C(=O)N3CCOCC3)CN(C(=O)OC(C)(C)C)C2)nc2ccccc21>>Cc1nnc(CCn2c(C(=O)N(CC(C)C)[C@H]3C[C@@H](C(=O)N4CCOCC4)CN(C(=O)OC(C)(C)C)C3)nc3ccccc32)o1 -US20120142714A1,1,COCOc1ccc2c(c1)OC(C)(c1ccc(O)cn1)C2.C[C@@H](CO)NC(=O)OC(C)(C)C>>COCOc1ccc2c(c1)OC(C)(c1ccc(OC[C@H](C)NC(=O)OC(C)(C)C)cn1)C2 -US07468391B2,6,CCOC(=O)C1CCC(C)(C)c2cc(C#Cc3ccc(CC(=O)OC(C)(C)C)cc3)c(C)cc21>>CCOC(=O)C1CCC(C)(C)c2cc(C#Cc3ccc(CC(=O)O)cc3)c(C)cc21 -US20060148858A1,6,COC(=O)Cc1cccc(OC)c1OCCCc1cn(-c2ncccc2C(F)(F)F)nc1C(C)C>>COc1cccc(CC(=O)O)c1OCCCc1cn(-c2ncccc2C(F)(F)F)nc1C(C)C -US20110201602A1,3,CN(C)CCCN(C)c1ccc(Br)cc1[N+](=O)[O-].FC(F)(F)C(F)(F)I>>CN(C)CCCN(C)c1ccc(C(F)(F)C(F)(F)F)cc1[N+](=O)[O-] -US06605620B1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COc1cccc(N)c1OC>>COc1cccc(NC2CCN(C(=O)OC(C)(C)C)CC2)c1OC -US04642375,2,CCCCCCCCCCCCN.COC(=O)c1ccc(C(=O)OC)cc1>>CCCCCCCCCCCCNC(=O)c1ccc(C(=O)OC)cc1 -US07417065B2,1,CC(C)Cc1ccc(-c2nc3ccc(CO)cc3o2)cc1C(F)(F)F.O=C(O)C1CNC1>>CC(C)Cc1ccc(-c2nc3ccc(CN4CC(C(=O)O)C4)cc3o2)cc1C(F)(F)F -US20120295934A1,2,NC1CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1.O=S(=O)(Cl)c1ccccc1Cl>>O=C1[C@H]2CC(NS(=O)(=O)c3ccccc3Cl)C[C@H]2CN1c1ccc(OC(F)(F)F)cc1 -US20120220592A1,2,CCN.COC(=O)CN(CCc1ccc(OCc2cccc(F)c2)c(OC)c1)CC1CC1>>CCNC(=O)CN(CCc1ccc(OCc2cccc(F)c2)c(OC)c1)CC1CC1 -US04734418,6,O=C1c2cnc(N3CCN(Cc4ccccc4)CC3)nc2CN1C1CCCCC1>>O=C1c2cnc(N3CCNCC3)nc2CN1C1CCCCC1 -US05344843,6,CCO/N=C(/C(=O)OCC)c1ccc(OCCOc2ccc3ccccc3c2)s1>>CCO/N=C(/C(=O)O)c1ccc(OCCOc2ccc3ccccc3c2)s1 -US04677129,7,COc1ccc(CN2C(=O)C3CC(c4ccc([N+](=O)[O-])cc4)(C3)C2=O)cc1>>COc1ccc(CN2C(=O)C3CC(c4ccc(N)cc4)(C3)C2=O)cc1 -US08808703B2,6,CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCC(F)(F)P(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC>>CCCCCCCCCCCCOC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCC(F)(F)P(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC -US07067508B2,2,NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(Br)CBr>>O=C(CBr)NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1 -US07585977B2,6,COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(S(=O)(=O)C(F)(F)F)cc3)ccc2c1>>O=S(=O)(c1ccc(-c2ccc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1)C(F)(F)F -US20110028509A1,2,NS(=O)(=O)c1cccc(Cl)c1.O=C(O)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1>>O=C(NS(=O)(=O)c1cccc(Cl)c1)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20100274051A1,2,Cc1cnc(N)s1.O=C(O)c1cc(Br)ccc1O>>Cc1cnc(NC(=O)c2cc(Br)ccc2O)s1 -US20090069328A1,7,COC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)c1cc(C#Cc2ccccc2)ccc1OC(C)C>>CC(C)Oc1ccc(C#Cc2ccccc2)cc1C(=O)NC(C)(CO)Cc1c[nH]c2ccccc12 -US08927587B2,7,N#Cc1ccc(-c2ccc(N)c([N+](=O)[O-])c2)cc1F>>N#Cc1ccc(-c2ccc(N)c(N)c2)cc1F -US20110046186A1,4,NNc1ncc(Cl)cc1Cl.O=C(CC(=O)C(F)(F)F)c1ccco1>>FC(F)(F)c1cc(-c2ccco2)n(-c2ncc(Cl)cc2Cl)n1 -US07776872B2,6,COc1cc2c(C)cccc2cc1C(C)C>>Cc1cccc2cc(C(C)C)c(O)cc12 -US20130079303A1,1,COc1ccc(N)cn1.COc1cnc(Cl)c(-c2nc(C)nc(N)n2)c1>>COc1cnc(Nc2ccc(OC)nc2)c(-c2nc(C)nc(N)n2)c1 -US20070259888A1,6,CCOC[C@@H]1CCCN(C[C@H]2CCCC[C@@H]2NC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)C1>>CCOC[C@@H]1CCCN(C[C@H]2CCCC[C@@H]2NC(=O)c2ccc(CN)cc2)C1 -US20130303764A1,2,CC[C@@](C)(Nc1ccnc(-c2c[nH]c3ncccc23)n1)C(=O)O.NCC(F)(F)F>>CC[C@@](C)(Nc1ccnc(-c2c[nH]c3ncccc23)n1)C(=O)NCC(F)(F)F -US20080015184A1,2,CC(C)Cn1c(CCCCN)nc2c(N)nc3ccccc3c21.O=C=Nc1ccccc1>>CC(C)Cn1c(CCCCNC(=O)Nc2ccccc2)nc2c(N)nc3ccccc3c21 -US07557213B2,1,COc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1F.FC(F)(F)c1cccc(CBr)n1>>COc1ccc(C(=O)c2cn(Cc3cccc(C(F)(F)F)n3)c3ccccc3c2=O)cc1F -US20040132727A1,2,C1CCNCC1.COc1cc2ncnc(Oc3ccc(OCC(=O)O)cc3)c2cc1OC>>COc1cc2ncnc(Oc3ccc(OCC(=O)N4CCCCC4)cc3)c2cc1OC -US06448247B1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(CCO)c1ccc(Cl)c(Cl)c1>>C=C(CCO)c1ccc(Cl)c(Cl)c1 -US20150080438A1,9,BrC(Br)(Br)Br.OCCCCCC1=C(c2cccc(O)c2)CCCc2cc(O)ccc21>>Oc1cccc(C2=C(CCCCCBr)c3ccc(O)cc3CCC2)c1 -US20100056527A1,2,Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12.Nc1ccc(CO)cc1>>Cc1cc(C(=O)Nc2ccc(CO)cc2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 -US04639521,1,CI.OC1CCC(O)CC1>>COC1CCC(O)CC1 -US20140163010A1,1,Clc1ncnc2c1cnn2CCN1CCCCC1.O=C1CCCN1>>O=C1CCCN1c1ncnc2c1cnn2CCN1CCCCC1 -US20110092505A1,1,COC(=O)c1cc(-c2ccnc(Cl)c2)nc(N2CCN(C(=O)OC(C)(C)C)CC2)c1.NC1CCCCC1>>COC(=O)c1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCN(C(=O)OC(C)(C)C)CC2)c1 -US08673940B2,6,COC(=O)c1ccc(NC(=O)c2ccc(Br)nc2)nc1>>O=C(O)c1ccc(NC(=O)c2ccc(Br)nc2)nc1 -US20100019229A1,3,CCCC[Sn](CCCC)(CCCC)c1cccs1.CCOP(=O)(OCC)c1ccsc1I>>CCOP(=O)(OCC)c1ccsc1-c1cccs1 -US20020045747A1,2,CC(C)COC(=O)[C@H](C)N.Cc1cccc(CC(=O)O)c1>>Cc1cccc(CC(=O)N[C@@H](C)C(=O)OCC(C)C)c1 -US20150133411A1,2,Cc1c(C(=O)O)cc(-c2ccccc2)n1CCCN1CCOCC1.Nc1cccc(C(F)(F)F)c1>>Cc1c(C(=O)Nc2cccc(C(F)(F)F)c2)cc(-c2ccccc2)n1CCCN1CCOCC1 -US05310920,1,ClCc1ccc(Cl)nc1.O=[N+]([O-])N=C1NCCN1C=Cc1ccc(OCC(F)(F)F)cc1>>O=[N+]([O-])N=C1N(C=Cc2ccc(OCC(F)(F)F)cc2)CCN1Cc1ccc(Cl)nc1 -US06432950B1,1,Clc1nc(Cl)c2c3c(sc2n1)CCCC3.NCc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(CNc2nc(Cl)nc3sc4c(c23)CCCC4)c1 -US05387710,7,O=C1CCCCc2ccc([N+](=O)[O-])cc21>>O=[N+]([O-])c1ccc2c(c1)C(O)CCCC2 -US06642226B2,1,C1CNCCN1.O=C1CCN(Cc2ccccc2)CC1c1ccc(Cl)cc1>>Clc1ccc([C@@H]2CN(Cc3ccccc3)CC[C@@H]2N2CCNCC2)cc1 -US20110144105A1,2,O=S(=O)(Cl)c1ccccc1.O=[N+]([O-])c1cnc2[nH]ccc2c1>>O=[N+]([O-])c1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1 -US06200831B1,2,NCCO.O=C=Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>O=C(NCCO)Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 -US20140100231A1,2,COc1nnc(C(C)(F)F)cc1CO.CS(=O)(=O)Cl>>COc1nnc(C(C)(F)F)cc1COS(C)(=O)=O -US20080275041A1,2,COCCN.O=C1Cc2cc(C(=O)O)ccc2N1>>COCCNC(=O)c1ccc2c(c1)CC(=O)N2 -US06693123B2,6,COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC(=O)c2cccnc2)cc1-c1ccccc1C>>CSCC[C@H](NC(=O)c1ccc(NC(=O)c2cccnc2)cc1-c1ccccc1C)C(=O)O -US20140228363A1,1,C[C@H]1CC(c2ccncc2[N+](=O)[O-])=C[C@@H](O[Si](C)(C)C(C)(C)C)[C@@]1(O)CBr>>C[C@H]1CC(c2ccncc2[N+](=O)[O-])=C[C@@H](O[Si](C)(C)C(C)(C)C)[C@@]12CO2 -US04046914,2,CCCCCCCCCCCCCCC(CO)OCC.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCCCCCCCCCCCCC(COS(=O)(=O)c1ccc(C)cc1)OCC -US05047540,2,CCCCCCCCCCCCCCCCOCC(CN)OC.O=S(=O)(Cl)CCCCl>>CCCCCCCCCCCCCCCCOCC(CNS(=O)(=O)CCCCl)OC -US20030130265A1,6,COC(=O)c1ccc2c(c1)nc(CCc1ccc(C#N)cc1)n2C>>Cn1c(CCc2ccc(C#N)cc2)nc2cc(C(=O)O)ccc21 -US06517984B1,1,CCBr.Cc1ccc(N(c2ccc(C)cc2)c2ccc(C(=O)O)cc2)cc1>>CCOC(=O)c1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1 -US05929089,1,O=C1Cc2ccccc2C1.O=c1oc(-c2cc(Cl)cc3c2OCCC3)nn1C1CCNCC1>>O=c1oc(-c2cc(Cl)cc3c2OCCC3)nn1C1CCN(C2Cc3ccccc3C2)CC1 -US20070066624A1,1,COC(=O)c1ccc(O)cc1.Cc1cc(Br)ncc1C=O>>COC(=O)c1ccc(Oc2cc(C)c(C=O)cn2)cc1 -US20070060607A1,2,CCOC(=O)c1cnc(N)c2c(COc3cccc(CNc4ccccc4)c3)csc12.NCCO>>Nc1ncc(C(=O)NCCO)c2scc(COc3cccc(CNc4ccccc4)c3)c12 -US20120046267A1,9,Brc1cccc2cnsc12.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2cccc3cnsc23)OC1(C)C -US05637731,1,CC(C)(C)[Si](C)(C)O[C@H]1CCN(CC#CCBr)C1=O.c1c[nH]cn1>>CC(C)(C)[Si](C)(C)O[C@H]1CCN(CC#CCn2ccnc2)C1=O -US20050009828A1,6,COCCOc1cc2cc(C(=O)NC3CCN(C(C)C)CC3)n(Cc3cc(-c4ccc(Cl)s4)on3)c2cn1>>CC(C)N1CCC(NC(=O)c2cc3cc(OCCO)ncc3n2Cc2cc(-c3ccc(Cl)s3)on2)CC1 -US04695571,7,CCN1C(=O)Cc2cc3c(cc21)C(=O)CO3>>CCN1C(=O)Cc2cc3c(cc21)C(O)CO3 -US20030225058A1,7,O=C1Cc2[nH]c3cc(F)ccc3c2CCN1>>Fc1ccc2c3c([nH]c2c1)CCNCC3 -US08143261B2,1,C[C@@H](N)C(N)=O.Nc1nc2nc(SCc3cccc(F)c3F)nc(Cl)c2s1>>C[C@@H](Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12)C(N)=O -US05108486,2,CNN.O=[N+]([O-])c1ccc(N=C=S)c(Cl)c1>>CN(N)C(=S)Nc1ccc([N+](=O)[O-])cc1Cl -US07816369B2,1,CNC.Nc1cc(Cl)ccc1[N+](=O)[O-]>>CN(C)c1ccc([N+](=O)[O-])c(N)c1 -US20130053364A1,3,COC(=O)c1cc(Br)ccc1CS(=O)(=O)c1ccccc1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>COC(=O)c1cc(-c2ccnn2C)ccc1CS(=O)(=O)c1ccccc1 -US06316475B1,2,C1CCNC1.O=C(Cl)c1ccc(-c2ccc(OCCCCl)cc2)cc1>>O=C(c1ccc(-c2ccc(OCCCCl)cc2)cc1)N1CCCC1 -US04826982,7,O=[N+]([O-])c1cc(F)c(Cl)c(Br)c1Cl>>Nc1cc(F)c(Cl)c(Br)c1Cl -US06313153B1,2,COc1cccc(CCN)c1.O=C(O)/C=C(/c1ccccc1)c1cccnc1>>COc1cccc(CCNC(=O)/C=C(/c2ccccc2)c2cccnc2)c1 -US20080280911A1,2,CC(C)(C)C(=O)Cl.COc1cc(N)ccc1F>>COc1cc(NC(=O)C(C)(C)C)ccc1F -US20060111351A1,2,Nc1cc(F)c(F)cc1C(=O)c1cccnc1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=C(c1cccnc1)c1cc(F)c(F)cc1NS(=O)(=O)c1ccc(Br)cc1 -US20120148502A1,6,CC(=O)OC1C(OCc2ccccc2)OC(COCc2ccccc2)C(OCc2ccccc2)C1OCc1ccccc1>>OC1C(OCc2ccccc2)OC(COCc2ccccc2)C(OCc2ccccc2)C1OCc1ccccc1 -US04711892,1,COc1ccc(C=CC(=O)NN)cn1.O=CC=Cc1ccc([N+](=O)[O-])o1>>COc1ccc(C=CC(=O)NN=CC=Cc2ccc([N+](=O)[O-])o2)cn1 -US04976770,2,COCCO.O=C(Cl)C1Oc2ccccc2Cc2ccccc2O1>>COCCOC(=O)C1Oc2ccccc2Cc2ccccc2O1 -US20150197527A1,2,CCCC(C)N.O=C(O)CSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccccc1>>CCCC(C)NC(=O)CSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccccc1 -US20120059002A1,4,Cc1cc(C=O)cc(C)c1OCCO.NC(=O)c1cc(CN2CCOCC2)ccc1N>>Cc1cc(-c2nc3ccc(CN4CCOCC4)cc3c(=O)[nH]2)cc(C)c1OCCO -US04958026,6,CCCN(CCC)CCc1ccc(N)c(OCc2ccccc2)c1>>CCCN(CCC)CCc1ccc(N)c(O)c1 -US06515027B1,2,C1CCC(NC2CCCCC2)CC1.COc1ccc([N+](=O)[O-])cc1OCC(=O)O>>COc1ccc([N+](=O)[O-])cc1OCC(=O)N(C1CCCCC1)C1CCCCC1 -US06025375,7,CCOC(=O)COc1cccc(C2CCCCC2=Cc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1>>CCOC(=O)COc1cccc(C2CCCCC2Cc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 -US04831148,1,COC(=O)C(C)Oc1ccc(O)cc1.Fc1cc(Cl)cnc1F>>COC(=O)C(C)Oc1ccc(Oc2ncc(Cl)cc2F)cc1 -US04336254,1,N=C(N)N.Nc1nc(Cl)cc(Cl)n1>>N=C(N)Nc1cc(Cl)nc(N)n1 -US20150183799A1,3,COc1cc(C)c2[nH]c(=O)c3sccc3c2c1Br.C[C@@H](NC(=O)OC(C)(C)C)c1ccc(Br)cc1>>COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)NC(=O)OC(C)(C)C)cc1 -US08461194B2,2,CCO.Cc1cc(Cl)ccc1Cn1nc(C(=O)O)c2ccccc21>>CCOC(=O)c1nn(Cc2ccc(Cl)cc2C)c2ccccc12 -US20100256097A1,2,CS(=O)(=O)Cl.O=C(CNCc1cccc(Br)n1)NC1CCCC1>>CS(=O)(=O)N(CC(=O)NC1CCCC1)Cc1cccc(Br)n1 -US04950762,1,CI.O=C(Nc1cc(F)cc(F)c1)c1ccccn1>>CN(C(=O)c1ccccn1)c1cc(F)cc(F)c1 -US06069149,6,COC(=O)c1ccc(OCCN(C)C)cc1>>CN(C)CCOc1ccc(C(=O)O)cc1 -US20110263571A1,1,CC1CCS(=O)(=O)N1.Cc1cnc(N2CCN(C(=O)c3ccc(Cl)cc3Br)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(Cl)cc3N3[C@H](C)CCS3(=O)=O)CC2)c(C)c1 -US20140302987A1,4,COc1ccc2c(c1)C(=NO)CC2>>COc1ccc2c(c1)C(=O)NCC2 -US20110053929A1,1,Brc1cn2ccnc2c(Br)n1.N#Cc1sc(NCCN)nc1N>>N#Cc1sc(NCCNc2nc(Br)cn3ccnc23)nc1N -US20070142362A1,1,CCCCCC1=NNCC1c1ccccc1.O=C(Cl)c1cccc2ccccc12>>CCCCCC1=NN(C(=O)c2cccc3ccccc23)CC1c1ccccc1 -US20100075959A1,2,COc1cccc2sc(N)nc12.Cc1ccc(C(=O)O)s1>>COc1cccc2sc(NC(=O)c3ccc(C)s3)nc12 -US20070219181A1,2,CC(C)(C)OC(=O)NN.Cc1ccc(C(CCCCl)C(=O)O)cc1>>Cc1ccc(C(CCCCl)C(=O)NNC(=O)OC(C)(C)C)cc1 -US20100075959A1,2,COc1cccc2sc(N)nc12.O=C(O)c1ccco1>>COc1cccc2sc(NC(=O)c3ccco3)nc12 -US20070244103A1,6,CC(C)(C)OC(=O)NCC1CN(Cc2ccccc2)CCO1>>CC(C)(C)OC(=O)NCC1CNCCO1 -US07276516B2,1,CC(C)[Si](C(C)C)(C(C)C)n1cc(Br)c2ccccc21.CN1CCNCC1>>CC(C)[Si](C(C)C)(C(C)C)n1cc(N2CCN(C)CC2)c2ccccc21 -US06320051B1,1,C=C(CN)CNc1cc(=O)c2ccccc2[nH]1.O=Cc1ccc(Cl)c(Cl)c1>>C=C(CNCc1ccc(Cl)c(Cl)c1)CNc1cc(=O)c2ccccc2[nH]1 -US05397801,2,Nc1ccc(Cl)cc1C(=O)c1ccccc1F.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>O=C(c1ccccc1F)c1cc(Cl)ccc1NS(=O)(=O)c1ccc([N+](=O)[O-])cc1 -US20100244012A1,3,CC(C)[Si](c1ccc2ccc(B3OC(C)(C)C(C)(C)O3)cc2c1)(C(C)C)C(C)C.O=C1c2ccccc2C(=O)c2cc(Cl)ccc21>>CC(C)[Si](c1ccc2ccc(-c3ccc4c(c3)C(=O)c3ccccc3C4=O)cc2c1)(C(C)C)C(C)C -US07001897B2,2,CC[C@H](C)[C@H](NC(=O)c1csc(N2CC(O)C2)n1)C(O[SiH](C)C)C(C)(C)C.CS(=O)(=O)Cl>>CC[C@H](C)[C@H](NC(=O)c1csc(N2CC(OS(C)(=O)=O)C2)n1)C(O[SiH](C)C)C(C)(C)C -US20150072976A1,6,COC(=O)c1ccc(-c2nc(CS(=O)(=O)C3CCCCC3)c(C)o2)cc1>>Cc1oc(-c2ccc(C(=O)O)cc2)nc1CS(=O)(=O)C1CCCCC1 -US20100249165A1,3,CCOc1cc(Br)cc(C=O)c1O.OB(O)c1cccs1>>CCOc1cc(-c2cccs2)cc(C=O)c1O -US06319939B1,6,CC(=O)Nc1ccc(C(C(C)C)n2cncn2)cc1>>CC(C)C(c1ccc(N)cc1)n1cncn1 -US20100190829A1,2,CN(C[C@@H](N)CC1CCCCC1)C(=O)OCC[Si](C)(C)C.O=C(O)c1cccc(Br)c1>>CN(C[C@H](CC1CCCCC1)NC(=O)c1cccc(Br)c1)C(=O)OCC[Si](C)(C)C -US20080090863A1,6,Cc1cnc(N[C@@H]2CC[C@H](NCc3ccccc3)CC2)cc1N1CCOCC1>>Cc1cnc(N[C@@H]2CC[C@H](N)CC2)cc1N1CCOCC1 -US20110160202A1,1,Fc1nccnc1C1CCOCC1.Nc1ccc(O)cc1>>Nc1ccc(Oc2nccnc2C2CCOCC2)cc1 -US20150057276A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(F)cc1F>>CC(C)(C)OC(=O)Nc1ccc(F)cc1F -US20140088156A1,2,CNC(=O)c1cc(Oc2ccc(N)cc2)ccn1.O=C=NC12CC3CC(CC(C3)C1)C2>>CNC(=O)c1cc(Oc2ccc(NC(=O)NC34CC5CC(CC(C5)C3)C4)cc2)ccn1 -US20060135576A1,1,Nc1cc(C(=O)NC2CC2)c(F)cc1F.O=Cc1cnc(Nc2ccc(C(=O)O)cn2)s1>>O=C(O)c1ccc(Nc2ncc(CNc3cc(C(=O)NC4CC4)c(F)cc3F)s2)nc1 -US20060178400A1,1,CC(=O)NC(C)C#Cc1cnc(Oc2ccc(O)cc2)s1.OCC1CCCC1>>CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CCCC3)cc2)s1 -US05026856,1,CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.Clc1cccc2c1CNC2>>CC1COc2c(N3Cc4cccc(Cl)c4C3)c(F)cc3c(=O)c(C(=O)O)cn1c23 -US20100311965A1,1,Cc1c(F)ccc2cnc(Cl)nc12.Cc1n[nH]c2cc(N)ccc12>>Cc1n[nH]c2cc(Nc3ncc4ccc(F)c(C)c4n3)ccc12 -US20140235628A1,6,CC(C)(C)OC(=O)N1CCC(O)(CCc2ccc(F)c(C#N)c2)CC1>>N#Cc1cc(CCC2(O)CC[NH2+]CC2)ccc1F -US20060276464A1,6,Cc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)NC1CCN(Cc2ccccc2)CC1>>Cc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)NC1CCNCC1 -US07279490B2,1,Cc1ccccc1CN1CCC(=O)CC1.O=c1[nH]c2ccccc2n1C1CCNCC1>>Cc1ccccc1CN1CCC(N2CCC(n3c(=O)[nH]c4ccccc43)CC2)CC1 -US20110039852A1,6,CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=NCc2ccccc2)NC#N)c1>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=NCc1ccccc1)NC#N -US20110046134A1,2,O=C(NCC(=O)N1CCNCC1)c1ccc(-c2ccccc2)cc1.O=C(O)c1c(F)cccc1C(F)(F)F>>O=C(NCC(=O)N1CCN(C(=O)c2c(F)cccc2C(F)(F)F)CC1)c1ccc(-c2ccccc2)cc1 -US20010001101A1,6,CCOC(=O)c1cnc2c3c(ccc2c1)C(=O)C([N+](=O)[O-])C=N3>>O=C(O)c1cnc2c3c(ccc2c1)C(=O)C([N+](=O)[O-])C=N3 -US20140066406A1,1,CP(C)(=O)c1ccc(Nc2ncc(C(F)(F)F)c(Cl)n2)cc1.NC12CC3CC(CC(C3)C1)C2>>CP(C)(=O)c1ccc(Nc2ncc(C(F)(F)F)c(NC34CC5CC(CC(C5)C3)C4)n2)cc1 -US20040220237A1,2,CCN.CCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1>>CCNC(=O)Cc1ccc(Oc2ccc(C(=O)NCC)cc2NS(=O)(=O)c2ccc(Cl)cc2Cl)c(OC)c1 -US20120121540A1,2,Cn1cnc(CN)c1.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl>>Cn1cnc(CNC(=O)c2nc3c(C(F)(F)F)cc(-c4ccco4)cn3c2Cl)c1 -US20120022044A1,9,O=C1Nc2cccc(F)c2CCC1I.[N-]=[N+]=[N-]>>[N-]=[N+]=NC1CCc2c(F)cccc2NC1=O -US06326516B1,2,COc1ccc(S(=O)(=O)Cl)cc1.N[C@@H]1CCCC[C@H]1C(=O)O>>COc1ccc(S(=O)(=O)N[C@@H]2CCCC[C@H]2C(=O)O)cc1 -US07902195B2,6,CCCOCCn1c(=O)c(N2CCN(CC(=O)OC(C)(C)C)CC2)nc2cnc(-c3ccc(OC)nc3)cc21>>CCCOCCn1c(=O)c(N2CCN(CC(=O)O)CC2)nc2cnc(-c3ccc(OC)nc3)cc21 -US03935209,1,Nc1cc(Cl)ccc1[N+](=O)[O-].Sc1nc[nH]n1>>Nc1cc(Sc2nc[nH]n2)ccc1[N+](=O)[O-] -US20090186870A1,1,C=CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3ccccc3Cl)sc2c1.COCCO>>COCCOCCS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3ccccc3Cl)sc2c1 -US03943124,4,C[C@]12CC=CC[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C#N)CC[C@@H]12.O=C(OO)c1cccc(Cl)c1>>C[C@]12C[C@H]3O[C@H]3C[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C#N)CC[C@@H]12 -US20030153566A1,2,COc1ccc(N(C)CC2CCOCC2)cc1N.O=C(N=C=S)c1ccccc1>>COc1ccc(N(C)CC2CCOCC2)cc1NC(=S)NC(=O)c1ccccc1 -US08431695B2,2,CCN=C=O.Nc1ncnn2c(C3CCNCC3)cc(-c3ccc4sc(Cc5ccccc5)nc4c3)c12>>CCNC(=O)N1CCC(c2cc(-c3ccc4sc(Cc5ccccc5)nc4c3)c3c(N)ncnn23)CC1 -US20150265722A1,3,C/C=C/B(O)O.COc1cc(C(=O)N2C=C(OS(=O)(=O)C(F)(F)F)C[C@H]2CO[Si](C)(C)C(C)(C)C)c([N+](=O)[O-])cc1O[Si](C(C)C)(C(C)C)C(C)C>>C/C=C/C1=CN(C(=O)c2cc(OC)c(O[Si](C(C)C)(C(C)C)C(C)C)cc2[N+](=O)[O-])[C@H](CO[Si](C)(C)C(C)(C)C)C1 -US08088930B2,1,COC(=O)c1ccnc(O)c1.Fc1cc2nc(-c3ccc(Cl)cc3)n(C(CBr)C3CCCCC3)c2cc1F>>COC(=O)c1ccnc(OCC(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c1 -US07582761B2,7,CC(=O)c1cnc(N2CCN(c3nc4ccc(C(F)(F)F)cc4[nH]3)CC2)c(Cl)c1>>CC(O)c1cnc(N2CCN(c3nc4ccc(C(F)(F)F)cc4[nH]3)CC2)c(Cl)c1 -US08188301B2,1,CCI.OC1(c2cc(Cl)cc(Cl)c2)CCNC1>>CCN1CCC(O)(c2cc(Cl)cc(Cl)c2)C1 -US20090093454A1,1,CC(C)=O.c1cnc2c(c1)CC[C@@H]1CCCN(Cc3nc4ccccc4n3C[C@H]3CCCNC3)[C@H]21>>CC(C)N1CCC[C@H](Cn2c(CN3CCC[C@H]4CCc5cccnc5[C@H]43)nc3ccccc32)C1 -US04728646,1,C1CNCCN1.CC1CN(c2nc(Cl)nc3c(SCc4ccccc4)ncnc23)CCO1>>CC1CN(c2nc(N3CCNCC3)nc3c(SCc4ccccc4)ncnc23)CCO1 -US06586617B1,1,CONS(=O)(=O)c1c(C)nn(C)c1Cl.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>CON(c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])S(=O)(=O)c1c(C)nn(C)c1Cl -US20140213586A1,1,COc1cc(N)cc(OCCO)c1.COc1ccc(C=O)cn1>>COc1cc(N=Cc2ccc(OC)nc2)cc(OCCO)c1 -US20120207729A1,7,O=[N+]([O-])c1c(Cl)nc(Cc2ccc(F)cc2)nc1-c1ccc2c(c1)OCO2>>Nc1c(Cl)nc(Cc2ccc(F)cc2)nc1-c1ccc2c(c1)OCO2 -US20090169558A1,3,CC1(C)OB(/C=C/C2CCCCC2)OC1(C)C.O=c1[nH]cnc2[nH]c(-c3ccnc(Cl)c3)cc12>>O=c1[nH]cnc2[nH]c(-c3ccnc(/C=C/C4CCCCC4)c3)cc12 -US20080275097A1,5,CC(=O)Oc1cccc2c1CCCN2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)Oc1cccc2c1CCCN2C(=O)OC(C)(C)C -US05736534,1,Clc1ccc2c(c1)NCC2.O=[N+]([O-])c1ccc2c(Cl)ncnc2c1>>O=[N+]([O-])c1ccc2c(N3CCc4ccc(Cl)cc43)ncnc2c1 -US08273341B2,6,COC(=O)NC(C(=O)OC)=C1CCOCC1>>COC(=O)NC(C(=O)O)=C1CCOCC1 -US08198267B2,1,COc1ccc[nH]c1=O.Cc1cc([N+](=O)[O-])ccc1F>>COc1cccn(-c2ccc([N+](=O)[O-])cc2C)c1=O -US09133105B2,2,Nc1cncc(Br)c1.O=C(O)CCCCCC(=O)O>>O=C(O)CCCCCC(=O)Nc1cncc(Br)c1 -US20110263592A1,6,CC(C)(C)OC(=O)N1CCN(CCc2ccc(F)cc2F)CC1>>Fc1ccc(CCN2CCNCC2)c(F)c1 -US20050277670A1,6,O=C(c1ccc(Br)cc1)C1CCN(C(=O)C(F)(F)F)CC1>>O=C(c1ccc(Br)cc1)C1CCNCC1 -US09029538B2,2,CCn1cc(C(=O)O)c(=O)n(-c2ccc(F)cc2)c1=O.COc1ccc2nccc(Oc3ccc(N)cc3)c2c1OC>>CCn1cc(C(=O)Nc2ccc(Oc3ccnc4ccc(OC)c(OC)c34)cc2)c(=O)n(-c2ccc(F)cc2)c1=O -US08853215B2,6,COC(=O)c1ncoc1C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(c2ocnc2C(=O)O)CC1 -US20090227799A1,7,N#Cc1ccc(Oc2ccc(F)cc2)s1>>NCc1ccc(Oc2ccc(F)cc2)s1 -US08211885B2,1,COCCCOc1ccccc1I.c1ccc2[nH]ccc2c1>>COCCCOc1ccccc1-n1ccc2ccccc21 -US07560569B2,2,Cc1ccc(CN)cc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>Cc1ccc(CNC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)cc1 -US20090069365A1,7,CCOC(=O)C1=C(c2ccsc2)CCN(Cc2ccccc2)C1>>CCOC(=O)C1CN(Cc2ccccc2)CCC1c1ccsc1 -US07858624B2,6,COCCCC[C@@](O)(c1ccccc1Oc1cccc(F)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>COCCCC[C@@](O)(c1ccccc1Oc1cccc(F)c1)[C@@H]1CCCNC1 -US20070149570A1,2,N#Cc1ccc(-c2ccc(OC(F)(F)F)c(CN[C@H]3CCNC[C@H]3c3ccccc3)c2)c(F)c1.O=C(O)CN1C(=O)CCCC1=O>>N#Cc1ccc(-c2ccc(OC(F)(F)F)c(CN[C@H]3CCN(C(=O)CN4C(=O)CCCC4=O)C[C@H]3c3ccccc3)c2)c(F)c1 -US20150148349A1,2,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)O.NC1CCCCC1>>CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)NC1CCCCC1 -US06288096B1,1,COC(=O)Nc1ccc(CCOS(C)(=O)=O)cc1.O=Cc1ccc(O)cc1>>COC(=O)Nc1ccc(CCOc2ccc(C=O)cc2)cc1 -US04168385,1,CC(C)(C)c1ccc(O)c(Cl)c1.COC(=O)C(Br)c1ccc(Oc2ccc(Cl)cc2)cc1>>COC(=O)C(Oc1ccc(C(C)(C)C)cc1Cl)c1ccc(Oc2ccc(Cl)cc2)cc1 -US07030262B2,3,CCOC(=O)CP(=O)(OCC)OCC.O=CCCCc1ccccc1>>CCOC(=O)/C=C/CCCc1ccccc1 -US07872006B2,2,COc1c(C(=O)O)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1.NN1CCOCC1>>COc1c(C(=O)NN2CCOCC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 -US20090221821A1,7,CCCn1c(=O)c2[nH]c(C34CCCC(C(=O)O)(CCC3)C4)nc2n(CCC)c1=O>>CCCn1c(=O)c2[nH]c(C34CCCC(CO)(CCC3)C4)nc2n(CCC)c1=O -US20150252030A1,1,COC(=O)CBr.Oc1cccnc1-c1ccsc1>>COC(=O)COc1cccnc1-c1ccsc1 -US05703243,7,CCOC(=O)OC(=O)[C@@H]1C[C@@H](OS(C)(=O)=O)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1CO -US09108939B2,6,CC(C)(C)OC(=O)N1CCC(=Cc2ccc([N+](=O)[O-])cc2)CC1>>O=[N+]([O-])c1ccc(C=C2CCNCC2)cc1 -US08481584B2,2,CCOC(=O)n1nc(N)c2cc(C(=O)OC(C)(C)C)sc21.O=C(O)c1ccc(N2CCOCC2)cc1>>CCOC(=O)n1nc(NC(=O)c2ccc(N3CCOCC3)cc2)c2cc(C(=O)OC(C)(C)C)sc21 -US20090163495A1,2,NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1.O=C(O)Cc1ccc(F)c(F)c1>>O=C(Cc1ccc(F)c(F)c1)NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1 -US20070072896A1,2,Nc1cnc2[nH]cc(-c3ccoc3)c2c1.O=C(Cl)c1ccc(F)cc1>>O=C(Nc1cnc2[nH]cc(-c3ccoc3)c2c1)c1ccc(F)cc1 -US20150210682A1,6,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCC)cc1CC2CC>>CCOc1cc2c(cc1OC)-c1cc(=O)c(C(=O)O)cn1C(CC)C2 -US08273499B2,1,O=C(c1ccc(F)cc1)c1cc(Cl)ccc1Cl.c1c[nH]cn1>>O=C(c1ccc(-n2ccnc2)cc1)c1cc(Cl)ccc1Cl -US07763636B2,2,CCOC(=O)c1cc2cc(F)ncc2n1Cc1cccc(F)c1.Cc1nc2cc(N)ccc2s1>>Cc1nc2cc(NC(=O)c3cc4cc(F)ncc4n3Cc3cccc(F)c3)ccc2s1 -US20140213586A1,1,CCOC(=O)CBr.Oc1ccc2cc[nH]c2c1>>CCOC(=O)COc1ccc2cc[nH]c2c1 -US20060229330A1,2,COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N.O=S(=O)(Cl)CCCCl>>COc1ccc(F)cc1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N -US20040038872A1,4,CC(C)NC(N)=S.CCOC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)OC1CCCC1)C(=O)N1C[C@H](Oc3cc(C(=O)CBr)nc4cc(OC)ccc34)C[C@H]1C(=O)N2>>CCOC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)OC1CCCC1)C(=O)N1C[C@H](Oc3cc(-c4csc(NC(C)C)n4)nc4cc(OC)ccc34)C[C@H]1C(=O)N2 -US05476952,1,CC(=O)[O-].O=C1c2ccccc2C(=O)c2c1cc(CBr)c1c2CCC1>>CC(=O)OCc1cc2c(c3c1CCC3)C(=O)c1ccccc1C2=O -US20150252038A1,2,CC(C)(C)N1CCC[C@@H](Oc2cc(F)c(C(=O)[O-])cc2C2CC2)C1.CS(N)(=O)=O>>CC(C)(C)N1CCC[C@@H](Oc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)C1 -US20020016337A1,2,CC(C)(C)OC(=O)N1CCCC(CNc2cccnc2)C1.O=C(Cl)c1ccco1>>CC(C)(C)OC(=O)N1CCCC(CN(C(=O)c2ccco2)c2cccnc2)C1 -US20040242572A1,2,CN1CCN(c2ccc(CCN)cn2)CC1.O=C(O)c1ccc(-c2ccc(Cl)cc2)cc1[N+](=O)[O-]>>CN1CCN(c2ccc(CCNC(=O)c3ccc(-c4ccc(Cl)cc4)cc3[N+](=O)[O-])cn2)CC1 -US20090281092A1,1,CCC1(F)CN(C2CCCC2)c2nc(Cl)ncc2NC1=O.CI>>CCC1(F)CN(C2CCCC2)c2nc(Cl)ncc2N(C)C1=O -US05532267,6,COC(=O)Cc1ccc(C(=O)NCc2ccc(C(=O)Oc3ccc4cc(C(=N)N)ccc4c3)o2)cc1>>N=C(N)c1ccc2cc(OC(=O)c3ccc(CNC(=O)c4ccc(CC(=O)O)cc4)o3)ccc2c1 -US07906510B2,1,CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(CC2CCNCC2)CCO1.N#CBr>>CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(CC2CCN(C#N)CC2)CCO1 -US20100256156A1,6,CCc1sc(C(=O)C(C)C)cc1C(Nc1ccc(C(=O)OC)cc1)C1CCCCC1>>CCc1sc(C(=O)C(C)C)cc1C(Nc1ccc(C(=O)O)cc1)C1CCCCC1 -US06124323,6,COc1ccc(C2CCN(CCCCc3ccccc3)CC2)cc1>>Oc1ccc(C2CCN(CCCCc3ccccc3)CC2)cc1 -US20090318467A1,1,C[O-].Cc1cc(-c2cccc(C(F)(F)F)c2)c(Cl)nc1C(=O)N1CCC(N2CCCC2)CC1>>COc1nc(C(=O)N2CCC(N3CCCC3)CC2)c(C)cc1-c1cccc(C(F)(F)F)c1 -US08969354B2,2,COC(=O)/C=C/C(=O)[O-].COC(=O)[C@@H](N)CS>>COC(=O)/C=C/C(=O)N[C@@H](CS)C(=O)OC -US04990526,3,COC(=O)CCC(=O)Cl.CSc1ccccc1>>COC(=O)CCC(=O)c1ccc(SC)cc1 -US08258131B2,7,CC1(C)C=C(c2ccc(F)cc2)c2ccc(NS(C)(=O)=O)cc2O1>>CC1(C)CC(c2ccc(F)cc2)c2ccc(NS(C)(=O)=O)cc2O1 -US08653263B2,2,Cc1cc(C)nc(N2CC3CNCC3C2)n1.Cc1noc(-c2cccc(F)c2C(=O)O)n1>>Cc1cc(C)nc(N2CC3CN(C(=O)c4c(F)cccc4-c4nc(C)no4)CC3C2)n1 -US20080280877A1,1,Clc1cnc(-c2ccccc2)cn1.O=C(c1ccccc1)N1CC(CO)(C(=O)O)C1>>O=C(c1ccccc1)N1CC(COc2cnc(-c3ccccc3)cn2)(C(=O)O)C1 -US20110124642A1,2,Nn1nc(C(F)(F)F)c2ccccc2c1=O.O=C(O)CSC12CC3CC(CC(C3)C1)C2>>O=C(CSC12CC3CC(CC(C3)C1)C2)Nn1nc(C(F)(F)F)c2ccccc2c1=O -US20140187553A1,3,COc1ccc(CNc2nnc(-c3ccc4c(c3)c(-c3cncc(Cl)n3)cn4S(=O)(=O)c3ccc(C)cc3)o2)cc1.OB(O)c1ccc(F)cc1>>COc1ccc(CNc2nnc(-c3ccc4c(c3)c(-c3cncc(-c5ccc(F)cc5)n3)cn4S(=O)(=O)c3ccc(C)cc3)o2)cc1 -US04987132,2,CC(C)(C)OC(=O)N1C(C(=O)O)CSC1c1cccnc1.COC(=O)[C@@H](N)CC(C)C>>COC(=O)[C@H](CC(C)C)NC(=O)C1CSC(c2cccnc2)N1C(=O)OC(C)(C)C -US20080051418A1,7,COC(=O)c1cc(OCc2ccc3ccccc3n2)n(C(C)C)n1>>CC(C)n1nc(CO)cc1OCc1ccc2ccccc2n1 -US08703776B2,2,CNCc1ccncc1.COC(=O)C(=O)Cl>>COC(=O)C(=O)N(C)Cc1ccncc1 -US08609647B2,6,CC1CN(C(=O)OCc2ccccc2)C12CCCN(C(=O)OC(C)(C)C)C2>>CC1CN(C(=O)OCc2ccccc2)C12CCCNC2 -US20090297472A1,2,CCCS(=O)(=O)[C@@]1(c2ccc(-c3ccccc3)cc2)C[C@H]2C(=O)N[C@]3(C(=O)O)C[C@H]3C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N2C1.NS(=O)(=O)C1CC1>>CCCS(=O)(=O)[C@@]1(c2ccc(-c3ccccc3)cc2)C[C@H]2C(=O)N[C@]3(C(=O)NS(=O)(=O)C4CC4)C[C@H]3C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N2C1 -US20100160308A1,2,CN1CCC(C(=O)O)CC1.NC(=O)c1sc(-n2cnc3ccc(CN4CCC(N)CC4)cc32)nc1-c1cccc(Cl)c1>>CN1CCC(C(=O)NC2CCN(Cc3ccc4ncn(-c5nc(-c6cccc(Cl)c6)c(C(N)=O)s5)c4c3)CC2)CC1 -US04987130,1,O=C1c2ccccc2C(=O)N1CCBr.OCCNCCO>>O=C1c2ccccc2C(=O)N1CCN(CCO)CCO -US07846960B2,1,CC(C)c1cnn(-c2ccccc2C(F)(F)F)c1CBr.COC(=O)c1cccc(C=Cc2ccc(O)cc2C)c1>>COC(=O)c1cccc(C=Cc2ccc(OCc3c(C(C)C)cnn3-c3ccccc3C(F)(F)F)cc2C)c1 -US08889741B2,2,COc1ccc(CNc2ccncn2)c(OC)c1.O=S(=O)(Cl)c1c(F)cc(F)cc1F>>COc1ccc(CN(c2ccncn2)S(=O)(=O)c2c(F)cc(F)cc2F)c(OC)c1 -US20090149484A1,7,Cn1cnc2ccc(Oc3ccc([N+](=O)[O-])cc3)cc2c1=O>>Cn1cnc2ccc(Oc3ccc(N)cc3)cc2c1=O -US06465481B1,1,CC(C)(C)OC(=O)N1CC2CC(CN(CCCC(O)c3ccc(C#N)cc3)C2)C1.COc1ccc(O)cc1OC>>COc1ccc(OC(CCCN2CC3CC(C2)CN(C(=O)OC(C)(C)C)C3)c2ccc(C#N)cc2)cc1OC -US20070249670A1,2,Cc1cccc(C)c1N=C=O.Nc1cc2ccccc2cc1C(=O)N(CC(=O)OCc1ccccc1)CC1CCCCC1>>Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N(CC(=O)OCc1ccccc1)CC1CCCCC1 -US08048909B2,3,CN(Cc1cc(Br)n(S(=O)(=O)c2cccc(Cl)c2)c1)C(=O)OC(C)(C)C.OB(O)c1ccsc1>>CN(Cc1cc(-c2ccsc2)n(S(=O)(=O)c2cccc(Cl)c2)c1)C(=O)OC(C)(C)C -US20070129334A1,1,C=CCBr.CC(C)=CCCn1c(Sc2nc3ccccc3[nH]2)nc2c(N)ncnc21>>C=CCn1c(Sc2nc3c(N)ncnc3n2CCC=C(C)C)nc2ccccc21 -US20050065179A1,7,CC(C)CN(CC(C)C)C(=O)C(C)(C)c1ccc([N+](=O)[O-])c(NCCCN(C)C)c1>>CC(C)CN(CC(C)C)C(=O)C(C)(C)c1ccc(N)c(NCCCN(C)C)c1 -US20140288046A1,1,CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn[nH]c2n1.Cc1nc(CCl)n(C)n1>>Cc1nc(Cn2nnc3c(N4CCC(F)(F)C4)nc(C(C)(C)C)nc32)n(C)n1 -US20140113882A1,1,COc1cncc2nc(-c3ccnc(Cl)c3)nc(N3CC[C@H](O)[C@H](O)C3)c12.Nc1ccccc1>>COc1cncc2nc(-c3ccnc(Nc4ccccc4)c3)nc(N3CC[C@H](O)[C@H](O)C3)c12 -US07291643B2,2,CS(=O)(=O)Cl.Cn1c(C#N)ccc1-c1ccc(N)c(C#N)c1>>Cn1c(C#N)ccc1-c1ccc(NS(C)(=O)=O)c(C#N)c1 -US05753664,1,Cn1c(S)nc2ccsc2c1=O.O=C(c1ccc(Cl)cc1)c1ccc(CBr)cc1>>Cn1c(SCc2ccc(C(=O)c3ccc(Cl)cc3)cc2)nc2ccsc2c1=O -US20060166990A1,3,Cc1ccc(C#N)cc1I.O=C(Cl)c1ccc([N+](=O)[O-])cc1Cl>>Cc1ccc(C#N)cc1C(=O)c1ccc([N+](=O)[O-])cc1Cl -US20140135318A1,6,CCCCN(CCCC)C(=O)c1cn(Cc2ccccc2)c(-c2ccc(C(=O)OC)cc2C(=O)N2Cc3ccccc3C[C@H]2CO)n1>>CCCCN(CCCC)C(=O)c1cn(Cc2ccccc2)c(-c2ccc(C(=O)O)cc2C(=O)N2Cc3ccccc3C[C@H]2CO)n1 -US06410580B1,1,CC(C)(C)OC(=O)N[C@H](CCCI)C(=O)OC(C)(C)C.O=C1NS(=O)(=O)c2ccccc21>>CC(C)(C)OC(=O)N[C@H](CCCN1C(=O)c2ccccc2S1(=O)=O)C(=O)OC(C)(C)C -US05597848,2,CO.O=C(O)CCCc1ccc(C(=O)C=Cc2ccccc2)cc1>>COC(=O)CCCc1ccc(C(=O)C=Cc2ccccc2)cc1 -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)Nc4ccc5c(c4)CCC5)c(F)c3)cc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NC(=O)Nc4ccc5c(c4)CCC5)c(F)c3)cc2C1=O -US20080188528A1,1,CC(C)c1cccc(-c2ccccc2CCl)c1.CCOC(=O)c1ccc[nH]c1=O>>CCOC(=O)c1cccn(Cc2ccccc2-c2cccc(C(C)C)c2)c1=O -US07235538B2,1,BrCc1ccccc1.Cn1c(=O)c2[nH]c(Cl)nc2n(C)c1=O>>Cn1c(=O)c2c(nc(Cl)n2Cc2ccccc2)n(C)c1=O -US04794188,3,CCCCCBr.O=Cc1ccc(Oc2ccc3ccccc3n2)cn1>>CCCCCC(O)c1ccc(Oc2ccc3ccccc3n2)cn1 -US08569317B2,7,CS(=O)CCOc1cccc(C=O)c1>>CS(=O)CCOc1cccc(CO)c1 -US20090221555A1,1,CCN(CCO)Cc1cc(Nc2nc(Cl)ncc2Cl)ccc1F.COc1cc2c(cc1N)CCN(CC(=O)N(C)C)CC2>>CCN(CCO)Cc1cc(Nc2nc(Nc3cc4c(cc3OC)CCN(CC(=O)N(C)C)CC4)ncc2Cl)ccc1F -US20100278833A1,9,COC(=O)c1sc(-n2cnc3ccc(OC)nc32)cc1OCc1ccccc1C(F)(F)F.N>>COc1ccc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2n1 -US08114873B2,2,Nc1ccc(Br)c2ccccc12.O=C(O)c1cc(F)cc(N2CCOCC2)c1>>O=C(Nc1ccc(Br)c2ccccc12)c1cc(F)cc(N2CCOCC2)c1 -US20110263598A1,3,CC(=O)OC1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(I)n[nH]c3c1)C(=O)N2>>COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCC(OC(C)=O)CC5)cc4)n[nH]c3c1)C(=O)N2 -US05698584,2,CSc1ccc(C(=O)C(C)(C)O)cc1.O=C(Cl)CCc1ccccc1>>CSc1ccc(C(=O)C(C)(C)OC(=O)CCc2ccccc2)cc1 -US20070111926A1,6,CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)CCC(=O)c1ccccc1)C(N)=O>>NC(=O)[C@@H](N)CCCCNC(=O)CCC(=O)c1ccccc1 -US20150191465A1,6,Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N2CCC(N3C(=O)c4ccccc4C3=O)C2)c1C#N>>Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N2CC[C@H](N)C2)c1C#N -US20100311760A1,1,C[O-].Fc1ccc(F)c(F)n1>>COc1nc(F)ccc1F -US04432979,1,CCBr.O=c1[nH]cc(-c2cnccn2)cc1Br>>CCn1cc(-c2cnccn2)cc(Br)c1=O -US20150266874A1,2,CC(C)(N)CO.Cc1ccc2sc(-c3nn(COCC[Si](C)(C)C)cc3C(=O)O)cc2c1>>Cc1ccc2sc(-c3nn(COCC[Si](C)(C)C)cc3C(=O)NC(C)(C)CO)cc2c1 -US08394795B2,2,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)O)c1F.Nc1cnc2[nH]ncc2c1>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]ncc3c2)c1F -US06514971B1,1,COCCOCCOc1cc2nncc(Cl)c2cc1OC.Cc1cc(F)c(N)cc1O>>COCCOCCOc1cc2nncc(Nc3cc(O)c(C)cc3F)c2cc1OC -US07615634B2,2,CCCC(=O)O.COc1ccccc1C(=O)c1cnc(NC2CCNCC2)nc1N>>CCCC(=O)N1CCC(Nc2ncc(C(=O)c3ccccc3OC)c(N)n2)CC1 -US08933018B2,6,CC(C)(C)OC(=O)NCc1ccc2c(c1)B(O)OC2>>NCc1ccc2c(c1)B(O)OC2 -US20140371199A1,2,CN1CCC(C2CCNCC2)CC1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1>>CN1CCC(C2CCN(C(=O)c3ccc(-c4ccc5ncc(-c6ccc(C#N)cc6)n5c4)cc3)CC2)CC1 -US07312341B2,2,Nc1ccc(-c2cn3ccnc3c(N)n2)cc1.O=C=Nc1ccccc1>>Nc1nc(-c2ccc(NC(=O)Nc3ccccc3)cc2)cn2ccnc12 -US05635485,6,COc1ccc2c(CCCCN3C(=O)c4ccccc4C3=O)ccnc2c1>>COc1ccc2c(CCCCN)ccnc2c1 -US20070072920A1,7,COCC=Cc1cc(OC)c(C[C@@H](C)NC(=O)C(F)(F)F)cc1OC>>COCCCc1cc(OC)c(C[C@@H](C)NC(=O)C(F)(F)F)cc1OC -US20080221157A1,8,OCCc1c[nH]c2ccccc12>>O=CCc1c[nH]c2ccccc12 -US20090118280A1,4,NCCc1ccc(Br)cc1.O=C(Cl)CCCCl>>O=C1CCCN1CCc1ccc(Br)cc1 -US04315764,1,CC(C)(C)C(O)C(C=C1CCCCC1)n1cncn1.ClCc1ccccc1Cl>>CC(C)(C)C(OCc1ccccc1Cl)C(C=C1CCCCC1)n1cncn1 -US20070254867A1,2,COc1cc(Cl)ccc1N.O=S(=O)(Cl)c1cccs1>>COc1cc(Cl)ccc1NS(=O)(=O)c1cccs1 -US20100197681A1,1,NC1CCCOC1.O=C(Nc1nc2cccc(Cl)n2n1)c1ccccc1>>O=C(Nc1nc2cccc(NC3CCCOC3)n2n1)c1ccccc1 -US05114966,2,COc1cc(C(=O)Cl)cc(OC)c1OC.Cc1c(C)c2c(c(C)c1OCc1ccccc1)CC(CCN)O2>>COc1cc(C(=O)NCCC2Cc3c(C)c(OCc4ccccc4)c(C)c(C)c3O2)cc(OC)c1OC -US20130065925A1,6,C[C@@H]1CN(Cc2c(Cl)cccc2C(F)(F)F)C[C@]1(CC(=O)OC(C)(C)C)C(=O)NC1CCN(CC2=CCCCC2)CC1>>C[C@@H]1CN(Cc2c(Cl)cccc2C(F)(F)F)C[C@]1(CC(=O)O)C(=O)NC1CCN(CC2=CCCCC2)CC1 -US20080269249A2,1,CN(C)C1CCNCC1.Nc1ncc(Br)nc1Br>>CN(C)C1CCN(c2nc(Br)cnc2N)CC1 -US20030225059A1,2,CC(=O)OC(C)=O.FC(F)(F)c1cc(CNCC2(c3ccccc3)CCC3(CC2)OCCO3)cc(C(F)(F)F)c1>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)CC1(c2ccccc2)CCC2(CC1)OCCO2 -US20090105307A1,6,COc1ccc(CN(C[C@H]2COC(N)=N2)c2cccc(Cl)c2)cc1>>NC1=N[C@@H](CNc2cccc(Cl)c2)CO1 -US20130184297A1,1,C1CCNCC1.O=C(/C=C/CBr)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CC2CCC(C1)O2>>O=C(/C=C/CN1CCCCC1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CC2CCC(C1)O2 -US07368471B2,3,CC(C)(C)c1ccc(Cn2ccc3cc(Br)ccc32)cc1.COc1cccc(B(O)O)c1>>COc1cccc(-c2ccc3c(ccn3Cc3ccc(C(C)(C)C)cc3)c2)c1 -US20090324581A1,7,CC(C)c1ccc(C(=O)O)cc1C#N>>CC(C)c1ccc(CO)cc1C#N -US07504162B2,6,c1ccc(Cn2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1>>c1ccc2c(c1)c1ccccc1n2-c1ccc2[nH]c3ccc(-n4c5ccccc5c5ccccc54)cc3c2c1 -US20130310384A1,7,CCOC(=O)c1ccc(CN([C@@H](CC)c2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)nc1>>CC[C@@H](c1ccccc1)N(Cc1ccc(CO)cn1)S(=O)(=O)c1ccc(Cl)cc1 -US08404677B2,1,CCOC(=O)c1c(C)nc(SC)nc1Cl.COc1cc(N)cc(OC)c1>>CCOC(=O)c1c(C)nc(SC)nc1Nc1cc(OC)cc(OC)c1 -US20110160056A1,1,CC(C)(C)C(O)C(CCCCCl)n1cncn1.Oc1ccc(Cl)c(Cl)c1>>CC(C)(C)C(O)C(CCCCOc1ccc(Cl)c(Cl)c1)n1cncn1 -US06867185B2,4,CCOC(=O)CC(=O)c1ccccc1.COc1cccc(N)c1>>COc1ccc2c(O)cc(-c3ccccc3)nc2c1 -US04582837,4,COc1cc(C(=O)O)ccc1NS(C)(=O)=O.Nc1cccnc1N>>COc1cc(-c2nc3ncccc3[nH]2)ccc1NS(C)(=O)=O -US20050176775A1,2,COCC(=O)O.Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1cccc(CN)c1>>COCC(=O)NCc1cccc(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1 -US04296036,7,CC1(C)C(=NO)C(=O)C2(C)CC(O)C12>>CC12CC(=NO)C(C)(C)C1C(O)C2 -US20110009454A1,3,CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1cccc(C=O)c1>>CCCCC=Cc1cccc(C#N)c1 -US20120077814A1,2,NS(=O)(=O)Cl.O=C(O[C@H]1C[C@H](c2ccc3c(N[C@H]4CCc5ccccc54)ncnn23)CC1CO)c1ccccc1>>NS(=O)(=O)OCC1C[C@@H](c2ccc3c(N[C@H]4CCc5ccccc54)ncnn23)C[C@@H]1OC(=O)c1ccccc1 -US20150218124A1,6,COc1cc(C#N)c(Cc2cc(C)cc(F)c2)c(C#N)c1O>>Cc1cc(F)cc(Cc2c(C#N)cc(O)c(O)c2C#N)c1 -US08350034B2,7,O=[N+]([O-])c1cnc2ccccc2c1N[C@H](CO)COCc1ccccc1>>Nc1cnc2ccccc2c1N[C@H](CO)COCc1ccccc1 -US20070270434A1,9,FC(F)(F)Oc1ccc(CBr)cc1.[C-]#N>>N#CCc1ccc(OC(F)(F)F)cc1 -US08334317B2,1,COc1cc(C=O)nn1-c1ccc(C(F)(F)F)cc1.C[C@@H](N)c1ccccc1>>COc1cc(CN[C@H](C)c2ccccc2)nn1-c1ccc(C(F)(F)F)cc1 -US08354444B2,8,CC(C)(CCO)C(=O)OCc1ccccc1>>CC(C)(CC=O)C(=O)OCc1ccccc1 -US08557830B2,6,COc1ccc(Cn2cnc3c(-c4cccnc4Oc4c(C)ccc5c(Nc6ccc(Cl)cc6)nccc45)ncnc32)cc1>>Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Oc1ncccc1-c1ncnc2[nH]cnc12 -US20130072427A1,1,Cc1c(Cl)ncnc1OC1CCN(C(=O)OC(C)(C)C)CC1.Cn1ncc2c1CNC2>>Cc1c(OC2CCN(C(=O)OC(C)(C)C)CC2)ncnc1N1Cc2cnn(C)c2C1 -US06410556B1,1,C[C@@H](c1ccccc1)N1Cc2sc(N)c(C(=O)OC(C)(C)C)c2C[C@H]1CN.O=Cc1ccc(Oc2ccccc2)cc1>>C[C@@H](c1ccccc1)N1Cc2sc(N)c(C(=O)OC(C)(C)C)c2C[C@H]1CNCc1ccc(Oc2ccccc2)cc1 -US20150157611A1,2,CCOC(=O)c1cn2cc(Br)ccc2n1.NCc1c(F)cccc1F>>O=C(NCc1c(F)cccc1F)c1cn2cc(Br)ccc2n1 -US06043243,2,CC(C)=CCC/C(C)=C/COc1ccc(C(=O)O)cc1.CCN1CCCC1CN>>CCN1CCCC1CNC(=O)c1ccc(OC/C=C(\C)CCC=C(C)C)cc1 -US20090203737A1,2,Cc1c[nH]c(-c2nc([C@H]3CCCNC3)no2)c1.Cc1oncc1C(=O)O>>Cc1c[nH]c(-c2nc([C@H]3CCCN(C(=O)c4cnoc4C)C3)no2)c1 -US04107329,9,CC(OCc1ccc2ccccc2c1)(C(=O)Cl)C(F)(F)F.N>>CC(OCc1ccc2ccccc2c1)(C(N)=O)C(F)(F)F -US04954339,7,CCCCCC(=CCCCCCCCN(C)C)CCCCC>>CCCCCC(CCCCC)CCCCCCCCN(C)C -US20120035134A1,2,N#C[C@@H](c1ccccc1-c1ccc(Cl)cc1)C1CCN(c2ccc(C(=O)O)cc2)CC1.NS(=O)(=O)c1ccc(N[C@H](CCN2CCOCC2)CSc2ccccc2)c(S(=O)(=O)C(F)(F)F)c1>>N#C[C@@H](c1ccccc1-c1ccc(Cl)cc1)C1CCN(c2ccc(C(=O)NS(=O)(=O)c3ccc(N[C@H](CCN4CCOCC4)CSc4ccccc4)c(S(=O)(=O)C(F)(F)F)c3)cc2)CC1 -US20150210666A1,6,CCCCCCCC(=O)CCCCCC/C=C/[C@H](C(=O)N[C@@H](Cc1ccc(-c2ccccc2F)cc1)C(=O)O)[C@@](O)(CCC)C(=O)OC(C)(C)C>>CCCCCCCC(=O)CCCCCC/C=C/[C@H](C(=O)N[C@@H](Cc1ccc(-c2ccccc2F)cc1)C(=O)O)[C@@](O)(CCC)C(=O)O -US20150152108A1,1,O=C(Nc1cccnc1)N1c2nc(Cl)ccc2N2CC[C@H]1C2.OC[C@H]1COCCN1>>O=C(Nc1cccnc1)N1c2nc(N3CCOC[C@@H]3CO)ccc2N2CC[C@H]1C2 -US08327467B2,1,Nc1ccc2[nH]ncc2c1.O=C(O)c1ccc(CCc2ccccc2)cc1I>>O=C(O)c1ccc(CCc2ccccc2)cc1Nc1ccc2[nH]ncc2c1 -US08258134B2,2,CC(C)(O)Cn1ccc(N)n1.O=C(O)C(CC1CCCC1)n1ncc(Oc2ccccc2C(=O)N2CCCC2)cc1=O>>CC(C)(O)Cn1ccc(NC(=O)C(CC2CCCC2)n2ncc(Oc3ccccc3C(=O)N3CCCC3)cc2=O)n1 -US20140066406A1,1,CC(C)S(=O)(=O)c1ccccc1Nc1cc(Cl)ncc1C(F)(F)F.CP(C)(=O)c1ccc(N)c(OC(F)(F)F)c1>>CC(C)S(=O)(=O)c1ccccc1Nc1cc(Nc2ccc(P(C)(C)=O)cc2OC(F)(F)F)ncc1C(F)(F)F -US06479531B1,6,COC(=O)c1cccc(CCc2nc(-c3ccccc3C)[nH]c2C(=O)NC23CC4CC(CC(C4)C2)C3)c1>>Cc1ccccc1-c1nc(CCc2cccc(C(=O)O)c2)c(C(=O)NC23CC4CC(CC(C4)C2)C3)[nH]1 -US05721267,1,CN.OCCCn1c(C=Cc2ccsc2)cc2ccccc21>>CNCCCn1c(C=Cc2ccsc2)cc2ccccc21 -US20110201643A1,6,COC(=O)c1ccc2c(c1)CCN(C(=O)OCc1ccccc1)C2>>O=C(O)c1ccc2c(c1)CCN(C(=O)OCc1ccccc1)C2 -US07304046B2,7,COC(=O)c1cc2c([N+](=O)[O-])c(OC)ccc2n1C>>COC(=O)c1cc2c(N)c(OC)ccc2n1C -US06323222B1,2,NC(CC(=O)O)c1cccc(Cl)c1.O=C(Cl)Cc1ccccc1>>O=C(O)CC(NC(=O)Cc1ccccc1)c1cccc(Cl)c1 -US04511655,2,C=CCC1C(=O)C=CC1(C)O.CC(=O)Cl>>C=CCC1C(=O)C=CC1(C)OC(C)=O -US20070123504A1,2,CCC(N)C(=O)O.O=C(Cl)c1ccccc1Cl>>CCC(NC(=O)c1ccccc1Cl)C(=O)O -US20120172376A1,7,Nc1ccc(C2=CCOCC2)cn1>>Nc1ccc(C2CCOCC2)cn1 -US20150065517A1,3,COC(=O)CC1CCC(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.COc1ncc(Nc2ccc(Br)nc2)cc1F>>COC(=O)CC1CCC(c2ccc(-c3ccc(Nc4cnc(OC)c(F)c4)cn3)cc2)CC1 -US20100216788A1,6,CN(CCn1ccc2ncnc(Nc3ccc(Oc4cccc(Cl)c4)c(Cl)c3)c21)C(=O)OC(C)(C)C>>CNCCn1ccc2ncnc(Nc3ccc(Oc4cccc(Cl)c4)c(Cl)c3)c21 -US04670190,4,C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C.OO>>C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)[C@@H]5O[C@@H]5[C@]4(C)[C@H]3CC[C@]12C -US20120289500A1,2,CC1CN(c2nn(N)c(=O)c3ccccc23)CC(C)O1.O=C(O)Cc1cc(F)cc(F)c1>>CC1CN(c2nn(NC(=O)Cc3cc(F)cc(F)c3)c(=O)c3ccccc23)CC(C)O1 -US05756813,2,CC1CCCCC1OC(=O)c1cc(N)ccc1Cl.O=C(Cl)c1ccccc1>>CC1CCCCC1OC(=O)c1cc(NC(=O)c2ccccc2)ccc1Cl -US20110301155A1,6,Cn1nc(N2C(=O)c3ccccc3C2=O)c2cc(-c3ncccc3Cl)ccc21>>Cn1nc(N)c2cc(-c3ncccc3Cl)ccc21 -US20030018064A1,6,CCOC(=O)CCc1coc2cc(OCCc3cccc(NC)n3)ccc12>>CNc1cccc(CCOc2ccc3c(CCC(=O)O)coc3c2)n1 -US07863302B2,3,CN(C)C=O.Fc1cccc(Br)c1>>O=Cc1c(F)cccc1Br -US20100331293A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(N2CCOCC2)nc1.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>Cc1c(-c2ccc(N3CCOCC3)nc2)nc2cc(F)cc(F)c2c1Cl -US20070249649A1,7,CC(C)(CO[Si](C)(C)C(C)(C)C)c1ccc([N+](=O)[O-])cc1>>CC(C)(CO[Si](C)(C)C(C)(C)C)c1ccc(N)cc1 -US07199238B2,1,Clc1ccc(Nc2nc(Cl)nc(Cl)n2)cc1.Nc1ccccc1>>Clc1ccc(Nc2nc(Cl)nc(Nc3ccccc3)n2)cc1 -US08530517B2,6,CCCCCC=CCC=CCCCCCCCC(=O)Oc1ccc(-c2ccc(/C=C/C(=O)OC(C)(C)C)cc2)cc1C12CC3CC(CC(C3)C1)C2>>CCCCCC=CC/C=C/CCCCCCCC(=O)Oc1ccc(-c2ccc(C=CC(=O)O)cc2)cc1C12CC3CC(CC(C3)C1)C2 -US05929085,7,COC(=O)C1Cc2ccc([N+](=O)[O-])cc2CN1>>O=[N+]([O-])c1ccc2c(c1)CNC(CO)C2 -US05342846,6,CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc(N3CCC(n4ccnn4)C3)c(F)cc2c1=O>>O=C(O)c1cn(-c2ccc(F)cc2F)c2nc(N3CCC(n4ccnn4)C3)c(F)cc2c1=O -US05721245,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc2c(c1)cc1n2CCNC1>>CC(C)(C)OC(=O)N1CCn2c(cc3ccccc32)C1 -US20020099078A1,1,ClCCOc1cccc2[nH]ccc12.Fc1ccc2[nH]cc(CC3CCNCC3)c2c1>>Fc1ccc2[nH]cc(CC3CCN(CCOc4cccc5[nH]ccc45)CC3)c2c1 -US05814653,7,O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccc(F)cc1>>Nc1ccc(NC(=O)c2ccc(F)cc2)cc1 -US04699905,1,CC(C)(C)OC(=O)CBr.O=C1NCC(c2cccc3ccccc23)SCC1N1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)CN1CC(c2cccc3ccccc23)SCC(N2C(=O)c3ccccc3C2=O)C1=O -US20140018393A1,6,CC(C)(C)OC(=O)N1CCCC(CN[C@@H]2C[C@H]2c2ccccc2)CC1>>c1ccc([C@@H]2C[C@H]2NCC2CCCNCC2)cc1 -US20030073862A1,1,COC(=O)c1cc(O)ccc1[N+](=O)[O-].OCc1cccs1>>COC(=O)c1cc(OCc2cccs2)ccc1[N+](=O)[O-] -US20070203159A1,3,CCCC[Sn](CCCC)(CCCC)c1ccco1.COc1ccc(Cn2cnc3c(Cl)nc(C(F)(F)F)nc32)cc1>>COc1ccc(Cn2cnc3c(-c4ccco4)nc(C(F)(F)F)nc32)cc1 -US20060020003A1,1,CN(Cc1ccc(-c2ccc(O)c(Br)c2)cc1)C(=O)c1cn(C)c2ccccc12.N#CCBr>>CN(Cc1ccc(-c2ccc(OCC#N)c(Br)c2)cc1)C(=O)c1cn(C)c2ccccc12 -US20100234351A1,1,BrCCOC1CCCCO1.OCCCOCc1ccccc1>>c1ccc(COCCCOCCOC2CCCCO2)cc1 -US20090318410A1,1,COc1ccc(-c2ccc3nc(C)c(-c4ccc(Br)cc4)n3n2)cc1OC.c1cn[nH]c1>>COc1ccc(-c2ccc3nc(C)c(-c4ccc(-n5cccn5)cc4)n3n2)cc1OC -US20140349996A1,2,CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)O.C[C@H]1CNCCN1c1ncnc2c1[C@H](C)CC2>>C[C@H]1CN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)OC(C)(C)C)CCN1c1ncnc2c1[C@H](C)CC2 -US20110112120A9,1,CC1(C)Cc2cc(B(O)O)ccc2O1.CCCc1nc[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1ncn(-c2ccc3c(c2)CC(C)(C)O3)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US06017926,4,CCOC(=O)CN(CCCC(C)=O)C(=O)OC(C)(C)C.Nc1ncccc1C=O>>CCOC(=O)CN(CCCc1ccc2cccnc2n1)C(=O)OC(C)(C)C -US05080905,1,CI.Nc1cccc2c(=O)[nH]c3ccccc3c(=O)c12>>Cn1c(=O)c2cccc(N)c2c(=O)c2ccccc21 -US20080293706A1,2,CC(C)CS(=O)(=O)Cl.O=S(=O)(Nc1cncc(-c2ccc3ncc(N4CCNCC4)nc3c2)c1)c1ccccc1>>CC(C)CS(=O)(=O)N1CCN(c2cnc3ccc(-c4cncc(NS(=O)(=O)c5ccccc5)c4)cc3n2)CC1 -US20130296327A1,2,CN1CCN(c2cc(-c3ccc4c(c3)CNCC4)nc(N)n2)CC1.O=C(O)CC1CCC1>>CN1CCN(c2cc(-c3ccc4c(c3)CN(C(=O)CC3CCC3)CC4)nc(N)n2)CC1 -US05266700,3,COc1cc2ccccc2nc1Br.COc1cc2ccccc2nc1[Sn](C)(C)C>>COc1cc2ccccc2nc1-c1nc2ccccc2cc1OC -US20050085472A1,3,CNC1=NC=NC2C1C(I)=CN2CCC(=O)OC(C)(C)C.OB(O)c1cccc(O)c1>>CNC1=NC=NC2C1C(c1cccc(O)c1)=CN2CCC(=O)OC(C)(C)C -US07144899B2,6,CC(C)(C)OC(=O)CN[C@@H](C(=O)N1CC[C@H]1C(=O)NCc1cc(Cl)ccc1-n1cncn1)C1CCCCC1>>O=C(O)CN[C@@H](C(=O)N1CC[C@H]1C(=O)NCc1cc(Cl)ccc1-n1cncn1)C1CCCCC1 -US06013663,2,C[C@@H](NC(=O)NCCCCC1CCSS1)C(=O)O.NS(N)(=O)=O>>C[C@@H](NC(=O)NCCCCC1CCSS1)C(=O)NS(N)(=O)=O -US04256760,1,CC(=O)C1(O)C=CC=CC1C(=O)O.O=C1OC(Br)c2ccccc21>>CC(=O)C1(O)C=CC=CC1C(=O)OC1OC(=O)c2ccccc21 -US04031226,2,C1CN1.O=C(Cl)c1ccc(F)cc1[N+](=O)[O-]>>O=C(c1ccc(F)cc1[N+](=O)[O-])N1CC1 -US06433175B1,3,CN(C)C=O.Clc1ccc2[nH]ccc2c1>>O=Cc1c[nH]c2ccc(Cl)cc12 -US08299085B2,1,CC(C)C(N)CO.CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc2c1=O>>CC(C)C(CO)Nc1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1[N+](=O)[O-] -US07919653B2,9,BrC(Br)(Br)Br.OCCOCCOCCOCCOCCOCc1ccccc1>>BrCCOCCOCCOCCOCCOCc1ccccc1 -US08969345B2,1,C/C(C#N)=C1/c2ccc(CBr)cc2COc2cc(F)ccc21.COCc1nc2ccccc2[nH]1>>COCc1nc2ccccc2n1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)C#N -US05428044,1,CC(=O)C(=O)O.Cc1cc(Nc2ccn(-c3ccccc3)n2)cc(C)c1O>>CC(=O)C(=O)Oc1c(C)cc(Nc2ccn(-c3ccccc3)n2)cc1C -US20090018103A1,6,CN(C[C@H](C[C@@H]1CC[C@@H](F)CC1)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CN(C[C@@H](N)C[C@@H]1CC[C@@H](F)CC1)C(=O)OCc1ccccc1 -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.COc1cccc(OC)c1N=C=O>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)Nc3c(OC)cccc3OC)CC2)nc1C(F)(F)F -US20080070920A1,1,COc1ccc(CNc2cc(CO)cc(Cl)n2)cc1.Cc1cc(C=CC#N)cc(C(=O)c2[nH]c(=O)[nH]c(=O)c2C(C)C)c1>>COc1ccc(CNc2cc(Cn3c(C(=O)c4cc(C)cc(C=CC#N)c4)c(C(C)C)c(=O)[nH]c3=O)cc(Cl)n2)cc1 -US20110178304A1,8,CC(O)c1ccc2c(c1)NC(=O)CC2>>CC(=O)c1ccc2c(c1)NC(=O)CC2 -US20090181942A1,6,CCOC(=O)CC1CCN(C(=O)CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c(C4=NNNN4C)ccc32)CC1>>COc1cccc([C@H]2O[C@H](CCC(=O)N3CCC(CC(=O)O)CC3)c3ccc(C4=NNNN4C)n3-c3ccc(Cl)cc32)c1OC -US20100160255A1,2,CC(C)N1C(=O)CC2(CCCN(C3CCN(C(=O)c4c(N)sc5c4CCCC5=O)CC3)C2)C1=O.CC(C)N=C=O>>CC(C)NC(=O)Nc1sc2c(c1C(=O)N1CCC(N3CCCC4(CC(=O)N(C(C)C)C4=O)C3)CC1)CCCC2=O -US08536187B2,5,CC[C@@H](N)c1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC[C@@H](NC(=O)C(F)(F)F)c1ccccc1 -US20080255195A1,3,O=[N+]([O-])c1c(F)cc(Br)cc1F.OB(O)C1CC1>>O=[N+]([O-])c1c(F)cc(C2CC2)cc1F -US04599357,2,CC(=O)SCC(C)C(=O)Cl.CCOC(=O)C1Cc2cc(OC)ccc2N1>>CCOC(=O)C1Cc2cc(OC)ccc2N1C(=O)C(C)CSC(C)=O -US07807671B2,3,CCCC[Sn](CCCC)(CCCC)c1cc(C(=O)OCC)[nH]n1.O=C(C(=O)N1CCN(c2nnnn2-c2ccccc2)CC1)c1c[nH]c2c(Br)ncc(F)c12>>CCOC(=O)c1cc(-c2ncc(F)c3c(C(=O)C(=O)N4CCN(c5nnnn5-c5ccccc5)CC4)c[nH]c23)n[nH]1 -US20140094493A1,6,COCOc1ccc2cc(COCC3CC3)ccc2c1>>Oc1ccc2cc(COCC3CC3)ccc2c1 -US20110086834A1,1,CI.Nc1ncc(Cl)c(Nc2cc(I)ccc2OC2CCOCC2)n1>>CN(c1cc(I)ccc1OC1CCOCC1)c1nc(N)ncc1Cl -US06660759B1,6,CC(C)(C)[Si](C)(C)O[C@@H]1C[C@H](C(=O)OC(C(=O)c2ccccc2)c2ccccc2)N(C(=O)OCc2ccccc2)C1>>O=C(c1ccccc1)C(OC(=O)[C@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1)c1ccccc1 -US08329682B2,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCC1)CCC2.O=C1Cc2cc(-c3ccccc3)ccc2N1>>Cc1c(/C=C2\C(=O)Nc3ccc(-c4ccccc4)cc32)[nH]c2c1C(=O)N(CCN1CCCC1)CCC2 -US04977175,4,CNc1cc(C)ccc1N.O=CO>>Cc1ccc2ncn(C)c2c1 -US08188139B2,6,COCCOc1ccc2c(c1)CN(C(=O)OC(C)(C)C)C2>>COCCOc1ccc2c(c1)CNC2 -US20130237525A1,1,COc1cccc(OC)c1C1CCCC(=O)N1.FC(F)Oc1ccc(CBr)cn1>>COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccc(OC(F)F)nc1 -US08410123B2,1,CCOC(=O)[C@@H](C)Oc1cc(Cl)nc(SCc2cccc(F)c2F)n1.NS(=O)(=O)N1CCC1>>CCOC(=O)[C@@H](C)Oc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1 -US20140323470A1,2,CC(C)(C)c1cc(N)n(-c2cn(CCOC3CCCCO3)cn2)n1.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)(C)c1cc(NC(=O)OCC(Cl)(Cl)Cl)n(-c2cn(CCOC3CCCCO3)cn2)n1 -US20120165310A1,1,Nc1ncnc2c1c(-c1cccc(OCC34CCC(CC3)O4)c1)cn2C1CCNCC1.O=C1COC1>>Nc1ncnc2c1c(-c1cccc(OCC34CCC(CC3)O4)c1)cn2C1CCN(C2COC2)CC1 -US06831193B2,1,Cc1ccc(Oc2cccc(C=O)c2)cc1.N[C@H]1CCCc2ccccc21>>Cc1ccc(Oc2cccc(CN[C@H]3CCCc4ccccc43)c2)cc1 -US04399134,1,CC(=O)NC1CCNCC1.CC1CCc2c(Br)c(F)cc3c(=O)c(C(=O)O)cn1c23>>CC(=O)NC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2CCC4C)CC1 -US20060074095A1,1,NC(=O)c1ccc(Nc2nc(Cl)nc3[nH]cnc23)cc1.N[C@H]1CC[C@H](N)CC1>>NC(=O)c1ccc(Nc2nc(N[C@@H]3CC[C@@H](N)CC3)nc3[nH]cnc23)cc1 -US20120208819A1,3,COc1ccc(CNc2ncnc3ccc(B4OC(C)(C)C(C)(C)O4)cc23)c(OC)c1.O=C(NCc1ccc(F)c(F)c1)c1cccnc1NCc1cccc(Br)c1>>COc1ccc(CNc2ncnc3ccc(-c4cccc(CNc5ncccc5C(=O)NCc5ccc(F)c(F)c5)c4)cc23)c(OC)c1 -US08481725B2,7,CC(C)[C@H](NC(=O)C1(NC(=O)c2ccco2)CCCCC1)C(=O)O>>CC(C)[C@@H](CO)NC(=O)C1(NC(=O)c2ccco2)CCCCC1 -US20080312234A1,2,CS(=O)(=O)Nc1c(F)cc(CN)cc1C#N.O=C(O)C=Cc1ccc(C(F)(F)F)nc1Oc1ccccc1>>CS(=O)(=O)Nc1c(F)cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2Oc2ccccc2)cc1C#N -USRE045183E1,2,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.C[C@@H]1CC[C@@H](N(C(=O)Nc2ncc(Cl)s2)C2CCNCC2)CC1>>CC(=O)Nc1ccc(S(=O)(=O)N2CCC(N(C(=O)Nc3ncc(Cl)s3)[C@@H]3CC[C@@H](C)CC3)CC2)cc1 -US04499094,2,CCC(C)NC.O=C(O)c1cc2sccc2c(-c2ccccc2)n1>>CCC(C)N(C)C(=O)c1cc2sccc2c(-c2ccccc2)n1 -US04604390,6,CCN(CC)CCn1nc2c3c(c(N)ccc31)Sc1cc(OC)ccc1-2>>CCN(CC)CCn1nc2c3c(c(N)ccc31)Sc1cc(O)ccc1-2 -US04735957,3,CNc1nc(C=O)c(-c2ccncc2)s1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1nc(NC)sc1-c1ccncc1 -US06063782,1,C=Cn1c(C)c(C)c2cnnc(Cl)c21.OCc1ccccc1>>C=Cn1c(C)c(C)c2cnnc(OCc3ccccc3)c21 -US20130237519A1,2,COC(=O)c1ccc(F)c(N)c1.O=C(O)c1cnc2cc(Br)ccn12>>COC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(Br)ccn23)c1 -US20060183904A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)Cl)CC1.Cc1cc(Br)c(NC(C)C)cc1C>>Cc1cc(Br)c(N(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)C(C)C)cc1C -US20150252036A1,6,CCOC(=O)[C@H]1C[C@@H]1c1ccccc1>>O=C(O)[C@H]1C[C@@H]1c1ccccc1 -US20100317663A1,1,CNC(=O)c1ccccc1N.Cc1cnc(F)cc1I>>CNC(=O)c1ccccc1Nc1cc(F)ncc1C -US20070197512A1,2,CC(C)CC(Cl)C(=O)Cl.Cc1cc(C)c(O)c(N)c1>>Cc1cc(C)c(O)c(NC(=O)C(Cl)CC(C)C)c1 -US09073924B2,2,Cc1cc(C)c(CN)c(=O)[nH]1.Cc1nn(C2CC2)c2nc(Cl)cc(C(=O)O)c12>>Cc1cc(C)c(CNC(=O)c2cc(Cl)nc3c2c(C)nn3C2CC2)c(=O)[nH]1 -US05733913,2,CCCCCCCCN=C=O.CN1CCN(CCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(N)nc3n2)CC1>>CCCCCCCCNC(=O)Nc1nc2nc(NCCCN3CCN(C)CC3)ncc2cc1-c1c(Cl)cccc1Cl -US20080076918A1,2,C[C@@H]1COCCN1.O=C(O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nccnc12>>C[C@@H]1COCCN1C(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nccnc12 -US20090099181A1,3,C[Si](C)(C)C#Cc1cncc(C(=O)N=[S@@](C)(=O)c2ccccc2)c1.O=C(O)c1cccc(I)c1>>C[S@@](=O)(=NC(=O)c1cncc(C#Cc2cccc(C(=O)O)c2)c1)c1ccccc1 -US20100215616A1,7,COC(=O)c1cccc([N+](=O)[O-])c1N>>COC(=O)c1cccc(N)c1N -US20060041144A1,3,COc1ccc(B(O)O)cc1.O=[N+]([O-])c1cccnc1Cl>>COc1ccc(-c2ncccc2[N+](=O)[O-])cc1 -US20060111357A1,1,CNCCN(C)C.Cc1cc2ccccc2nc1Cl>>Cc1cc2ccccc2nc1N(C)CCN(C)C -US08314109B2,6,CCOC(=O)c1cn2cc(-c3ccc(CO)o3)ccc2n1>>O=C(O)c1cn2cc(-c3ccc(CO)o3)ccc2n1 -US08071650B2,7,CS(=O)(=O)Nc1ccccc1CC#N>>CS(=O)(=O)Nc1ccccc1CCN -US20050148670A1,3,CCOCOc1cc(B(O)O)cc2c1C(C)(C)CCC2(C)C.COC(=O)c1ccc2cc(C(=O)Cl)ccc2c1>>CCOCOc1cc(C(=O)c2ccc3cc(C(=O)OC)ccc3c2)cc2c1C(C)(C)CCC2(C)C -US20050131002A1,1,CSc1ncccc1NC(=O)CCCCCBr.Sc1nc2ccccc2o1>>CSc1ncccc1NC(=O)CCCCCSc1nc2ccccc2o1 -US20060247227A1,1,CC(C)(C)OC(=O)N1CCC(OC2CCNCC2)CC1.N#Cc1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1CCC(OC2CCN(c3ccc(C#N)cn3)CC2)CC1 -US08034812B2,2,Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1.O=C(O)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1)c1cccc(C(F)(F)F)c1 -US20140051681A1,3,CC1(C)OB(c2ccc(C3(C#N)CCOCC3)cc2)OC1(C)C.Nc1cnc(Br)cn1>>N#CC1(c2ccc(-c3cnc(N)cn3)cc2)CCOCC1 -US20140343032A1,6,OCC1(O)CC2COCC(C1)N2Cc1ccccc1>>OCC1(O)CC2COCC(C1)N2 -US06617346B1,9,COc1cc(Br)cc(CO)c1.[C-]#N>>COc1cc(C#N)cc(CO)c1 -US04826876,7,COc1ccc(Cc2cc(Sc3c(Cl)cc([N+](=O)[O-])cc3Cl)ccc2OC)cn1>>COc1ccc(Cc2cc(Sc3c(Cl)cc(N)cc3Cl)ccc2OC)cn1 -US20150111857A1,6,CC(C)(C)OC(=O)N1CCN(c2ncc(Cc3ccccc3)cn2)CC1>>c1ccc(Cc2cnc(N3CCNCC3)nc2)cc1 -US09107916B2,1,CCC(C)Br.OCc1ccc(Cl)cc1O>>CCC(C)Oc1cc(Cl)ccc1CO -US07157430B2,8,CC(C)[C@H](NC(=O)COc1cccc2ccccc12)C(=O)NC(CC(=O)OC(C)(C)C)C(O)CF>>CC(C)[C@H](NC(=O)COc1cccc2ccccc12)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)CF -US08173676B2,6,CCSCC(O)(C(Nc1cccc2nc(C)ccc12)c1ccc(Cl)c(OC)c1F)C(F)(F)F>>CCSCC(O)(C(Nc1cccc2nc(C)ccc12)c1ccc(Cl)c(O)c1F)C(F)(F)F -US20130280305A1,6,CCCCCCCC/C=C\CCCCCCCC(=O)OCCN(CCOC(=O)CCCCCCC/C=C\CCCCCCCC)C(=O)OC(C)(C)C>>CCCCCCCC/C=C\CCCCCCCC(=O)OCCNCCOC(=O)CCCCCCC/C=C\CCCCCCCC -US09156840B2,6,CC(C)(C)OC(=O)c1ccccc1CN1CN(c2ccccc2)C2(CCN(C(=O)OCc3ccccc3)CC2)C1=O>>CC(C)(C)OC(=O)c1ccccc1CN1CN(c2ccccc2)C2(CCNCC2)C1=O -US05827501,9,CC1(C)Oc2c(c(C(O)(c3c4c(c(SC(=O)C(C)(C)C)c5c3OC(C)(C)O5)OC(C)(C)O4)c3c4c(c(SC(=O)C(C)(C)C)c5c3OC(C)(C)O5)OC(C)(C)O4)c3c(c2SC(=O)C(C)(C)C)OC(C)(C)O3)O1>>CC1(C)Oc2c(c(C(c3c4c(c(SC(=O)C(C)(C)C)c5c3OC(C)(C)O5)OC(C)(C)O4)c3c4c(c(SC(=O)C(C)(C)C)c5c3OC(C)(C)O5)OC(C)(C)O4)c3c(c2SC(=O)C(C)(C)C)OC(C)(C)O3)O1 -US20150152096A1,10,CCOC(=O)C1=C(C)NC(c2ncns2)=NC1c1ccc(F)cc1Br.O=C1CCC(=O)N1Br>>CCOC(=O)C1=C(CBr)NC(c2ncns2)=NC1c1ccc(F)cc1Br -US20140100250A1,6,Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C(C)(O)C3CCN(C(=O)OC(C)(C)C)C3)s2)c1>>Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C(C)(O)C3CCNC3)s2)c1 -US20150191465A1,1,CNC1CN(C(=O)OC(C)(C)C)C1.C[C@H](N)c1nc2ccn(C)c2cc1Br>>C[C@H](N)c1nc2ccn(C)c2cc1N(C)C1CN(C(=O)OC(C)(C)C)C1 -US04448962,1,CCn1cc(C(=O)O)c(=O)c2cc(Cl)c(N3CCNCC3)cc21.O=C1OC(O)c2ccccc21>>CCn1cc(C(=O)O)c(=O)c2cc(Cl)c(N3CCN(C4OC(=O)c5ccccc54)CC3)cc21 -US06583096B1,3,CC(C)=CCCC(C)=CC=O.C[Mg+]>>CC(C)=CCCC(C)=CC(C)O -US05856327,4,CC(C)(C)OO.OCC=Cc1ccc(Cl)cc1>>OC[C@@H]1O[C@@H]1c1ccc(Cl)cc1 -US20150166549A1,6,CC(O[Si](C)(C)C(C)(C)C)c1oc(=O)c2ccccc2c1-c1ccccn1>>CC(O)c1oc(=O)c2ccccc2c1-c1ccccn1 -US05859007,6,CCOC(=O)c1cccc(C2(C(N)=O)C(=O)N(CC(=O)N(c3ccccc3)C(C)C)c3ccccc3N(c3ccccc3)C2=O)c1>>CC(C)N(C(=O)CN1C(=O)C(C(N)=O)(c2cccc(C(=O)O)c2)C(=O)N(c2ccccc2)c2ccccc21)c1ccccc1 -US20070161684A1,8,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)N[C@@H](C)C(C)C)cn1.O=C(OO)c1cccc(Cl)c1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)N[C@@H](C)C(C)C)c[n+]1[O-] -US07538120B2,2,CC(C)(C)OC(=O)NCCO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NCCOS(C)(=O)=O -US05466690,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCC3(C)C)nc1>>CC1(C)CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cn3)ccc21 -US06329381B1,6,COCCOc1nc(N)c2nc(OC)n(Cc3ccc(F)cc3)c2n1>>COCCOc1nc(N)c2nc(O)n(Cc3ccc(F)cc3)c2n1 -US07579347B2,2,Cc1nc(C(C)(C)C)ccc1/C=C/C(=O)O.Nc1ccc2cc[nH]c2c1>>Cc1nc(C(C)(C)C)ccc1/C=C/C(=O)Nc1ccc2cc[nH]c2c1 -US08901156B2,2,CC(C)(CN)c1nc(-c2ccccc2)cs1.O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1>>CC(C)(CNC(=O)c1cccc(-c2noc(C(F)(F)F)n2)c1)c1nc(-c2ccccc2)cs1 -US20090182029A1,2,Cc1[nH]c(C=NN=C2C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NCCCCCCCC(=O)O.Nc1ccccc1N>>Cc1[nH]c(C=NN=C2C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NCCCCCCCC(=O)Nc1ccccc1N -US20080269210A1,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.Cc1c(-c2cccc(OCCN3CCOCC3)c2)sc2c(N3CCOCC3)nc(Cl)nc12>>Cc1c(-c2cccc(OCCN3CCOCC3)c2)sc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc12 -US04563210,9,NC(=O)c1cnn(-c2ccc(Cl)cc2Cl)c1C(F)(F)F>>N#Cc1cnn(-c2ccc(Cl)cc2Cl)c1C(F)(F)F -US20140343059A1,3,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Br)o2)C(COc2cccnc2)C1.OB(O)c1ccccc1Cl>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3ccccc3Cl)o2)C(COc2cccnc2)C1 -US20030176454A1,1,Cc1ncn(-c2cccc(N)c2)n1.Clc1ncnc2c(-c3cccs3)cccc12>>Cc1ncn(-c2cccc(Nc3ncnc4c(-c5cccs5)cccc34)c2)n1 -US20120059001A1,6,COc1ccc(-c2nn(C(C)c3oc4ccccc4c(=O)c3-c3cccc(F)c3)c3ncnc(N)c23)cc1F>>CC(c1oc2ccccc2c(=O)c1-c1cccc(F)c1)n1nc(-c2ccc(O)c(F)c2)c2c(N)ncnc21 -US20120135088A1,3,COc1cc(C)c(C(=O)Cl)c(OC)c1OC.COc1ncc(Cl)c(C)c1Br>>COc1cc(C)c(C(=O)c2c(OC)ncc(Cl)c2C)c(OC)c1OC -US05530126,6,CCOC(=O)C(C)Oc1cc(-c2nn(C)c(C(F)(F)F)c2Cl)c(F)cc1Cl>>CC(Oc1cc(-c2nn(C)c(C(F)(F)F)c2Cl)c(F)cc1Cl)C(=O)O -US06528543B1,2,CN=C=O.NC(=O)C(CC1CCCC1)c1ccc(Cl)c([N+](=O)[O-])c1>>CNC(=O)NC(=O)C(CC1CCCC1)c1ccc(Cl)c([N+](=O)[O-])c1 -US20040029887A1,1,CC(C)Br.O=[N+]([O-])c1ccccc1O>>CC(C)Oc1ccccc1[N+](=O)[O-] -US08106215B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(F)(F)C[C@@H]3[C@H]2CN)c1.O=C(O)c1cnc2ccccn12>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(F)(F)C[C@@H]3[C@H]2CNC(=O)c2cnc3ccccn23)c1 -US20090156578A1,2,CN[C@H](C)c1sc2ccccc2c1C.O=C(O)C=Cc1cnc2c(c1)COCC(=O)N2>>Cc1c(C(C)N(C)C(=O)C=Cc2cnc3c(c2)COCC(=O)N3)sc2ccccc12 -US20080103141A1,2,CC(C)OC(=O)Cl.CS(=O)(=O)c1ccc(-c2cnc(NCC3CCNCC3)nc2)cc1>>CC(C)OC(=O)N1CCC(CNc2ncc(-c3ccc(S(C)(=O)=O)cc3)cn2)CC1 -US20080293701A1,7,COCCCOc1cc(Br)ccc1C(C)=O>>CCc1ccc(Br)cc1OCCCOC -US20130225646A1,2,CC(C)(C)OC(=O)NC(CN)c1ccccc1C(F)(F)F.O=C(O)Cn1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O>>CC(C)(C)OC(=O)NC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O)c1ccccc1C(F)(F)F -US20070208062A1,2,CS(=O)(=O)Cl.NCCOC[C@@H]1CC(c2ccc(Br)cn2)=NO1>>CS(=O)(=O)NCCOC[C@@H]1CC(c2ccc(Br)cn2)=NO1 -US07056932B2,1,CCOC(=O)C(OCC)n1cccc(N)c1=O.OB(O)c1ccccc1>>CCOC(=O)C(OCC)n1cccc(Nc2ccccc2)c1=O -US20090221555A1,1,CC1(C)CCC(=O)Nc2ccc(N)cc21.CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl>>CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)C(C)(C)CCC(=O)N3)ncc1Cl -US06855716B2,2,COCC1=C(C(=O)O)C(c2cccc(Cl)c2)NC(=O)N1.NCCCc1ccccc1>>COCC1=C(C(=O)NCCCc2ccccc2)C(c2cccc(Cl)c2)NC(=O)N1 -US04017503,2,O=C(Cl)OCCOCc1ccccc1.c1ccc2[nH]c(-c3cscn3)nc2c1>>O=C(OCCOCc1ccccc1)n1c(-c2cscn2)nc2ccccc21 -US20140135316A1,1,Cc1nnc2n1-c1ccccc1NC(C)C2.Clc1ccc(I)cc1>>Cc1nnc2n1-c1ccccc1N(c1ccc(Cl)cc1)C(C)C2 -US20140163035A1,1,CCOC(=O)c1c(Br)ccnc1Cl.C[O-]>>CCOC(=O)c1c(OC)ccnc1Cl -US20030207865A1,9,Cc1cc(C(=O)O)ccc1N=C1SC[C@H](CC(C)C)N1CC(C)C.N>>Cc1cc(C(N)=O)ccc1N=C1SC[C@H](CC(C)C)N1CC(C)C -US06147097,3,CC(=O)Cn1c(COCc2ccccc2)nc(C(C)C)c1Sc1cc(Cl)cc(Cl)c1.C[Mg+]>>CC(C)c1nc(COCc2ccccc2)n(CC(C)(C)O)c1Sc1cc(Cl)cc(Cl)c1 -US20050245592A1,10,CCOC(=O)c1cc(Br)c(C)cc1OCC.O=C1CCC(=O)N1Br>>CCOC(=O)c1cc(Br)c(CBr)cc1OCC -US05576440,1,Fc1ncccc1I.SCc1ccccc1>>Ic1cccnc1SCc1ccccc1 -US09050345B2,2,CS(=O)(=O)Cl.NC1(c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)CC1>>CS(=O)(=O)NC1(c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)CC1 -US20100041892A1,2,CC(C)(C)COC(=O)Cl.CCCCOc1cc(CCS(N)(=O)=O)n(Cc2ccc(Cl)cc2Cl)n1>>CCCCOc1cc(CCS(=O)(=O)NC(=O)OCC(C)(C)C)n(Cc2ccc(Cl)cc2Cl)n1 -US20130252882A1,3,COC(=O)c1cc(C2CC2)c2c(C)c(Cl)ccn2c1=O.OB(O)c1ccc(O)c(F)c1>>COC(=O)c1cc(C2CC2)c2c(C)c(-c3ccc(O)c(F)c3)ccn2c1=O -US04999378,1,COC(=O)c1ccc(OCC=O)cc1.Nc1ccc(Cl)cc1>>COC(=O)c1ccc(OCCNc2ccc(Cl)cc2)cc1 -US04851519,2,NC[C@H]1O[C@@H](n2cc(CCCl)c(=O)[nH]c2=O)C[C@@H]1O.O=C(Cl)Cc1c(Cl)cccc1Cl>>O=C(Cc1c(Cl)cccc1Cl)NC[C@H]1O[C@@H](n2cc(CCCl)c(=O)[nH]c2=O)C[C@@H]1O -US20090275570A1,2,CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3sc(-c4ccc(N5CCNCC5)cc4)cc23)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3sc(-c4ccc(N5CCN(S(C)(=O)=O)CC5)cc4)cc23)C1 -US20110021479A1,2,COCC(=O)Cl.O=C(N[C@@H]1CCCNC1)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COCC(=O)N1CCC[C@@H](NC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C1 -US05015637,7,O=Cc1cccn1NCc1ccncc1F>>OCc1cccn1NCc1ccncc1F -US20080293771A1,1,CN(C(=O)OCc1ccccc1)[C@@H]1CCNC1.O=C1CCC1>>CN(C(=O)OCc1ccccc1)[C@@H]1CCN(C2CCC2)C1 -US20050137243A1,6,COC(CCn1ncc2ccc(NC(=O)Cc3ccc(Oc4ccccc4)cc3)cc21)OC>>O=CCCn1ncc2ccc(NC(=O)Cc3ccc(Oc4ccccc4)cc3)cc21 -US20030208066A1,1,CCOC(=O)c1cnc2c(c(C)nn2C)c1Cl.COc1ccc(S(=O)(=O)NCc2cccnc2)cc1>>CCOC(=O)c1cnc2c(c(C)nn2C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 -US08822447B2,2,CCc1nn(-c2ccccc2)c2cc(N)ccc12.O=C(O)c1ccc2[nH]cnc2c1>>CCc1nn(-c2ccccc2)c2cc(NC(=O)c3ccc4[nH]cnc4c3)ccc12 -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.O=C(N1CCNCC1)N1CCOCC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(C(=O)N2CCOCC2)CC1 -USH0001638,1,O=C(O)c1c(F)c(F)c(F)c(F)c1F.OCC(F)(F)C(F)(F)C(F)(F)C(F)F>>O=C(O)c1c(F)c(F)c(OCC(F)(F)C(F)(F)C(F)(F)C(F)F)c(F)c1F -US20030082510A1,10,CC(=O)Oc1ccc2c(C)c(C)c(=O)oc2c1C.O=C1CCC(=O)N1Br>>CC(=O)Oc1ccc2c(C)c(CBr)c(=O)oc2c1C -US20120165334A1,4,Nc1cc(F)c(F)cc1N.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cc(F)c(F)cc2[nH]1 -US20110237573A1,9,CC(=O)N1CCN(c2ccc(NC(=O)Cc3ccc(I)cc3)nc2)CC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(=O)N1CCN(c2ccc(NC(=O)Cc3ccc(B4OC(C)(C)C(C)(C)O4)cc3)nc2)CC1 -US20150203483A1,7,COc1ccc(CC(C)=O)cc1OC>>COc1ccc(CC(C)O)cc1OC -US20140057836A1,2,COCC(C)(C)O.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COCC(C)(C)OC(=O)Oc1ccc([N+](=O)[O-])cc1 -US06162809,1,Cc1c(SCCCCl)ccnc1CSc1ccncc1.c1c[nH]cn1>>Cc1c(SCCCn2ccnc2)ccnc1CSc1ccncc1 -US05627202,2,CC[C@H]1CCN[C@@H]1C(=O)O.CSCC[C@H](N)C(=O)OC(C)C>>CC[C@H]1CCN[C@@H]1C(=O)N[C@@H](CCSC)C(=O)OC(C)C -US05663162,2,NCc1csc2cncn12.O=CO>>O=CNCc1csc2cncn12 -US20140249104A1,1,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(Br)cnc2F)C[C@@H](C(F)(F)F)O1.C[O-]>>COc1ncc(Br)cc1[C@]1(C)C[C@@H](C(F)(F)F)OC(NC(=O)OC(C)(C)C)=N1 -US20080058309A1,1,C[Si](C)(C)CCOCCl.Nc1c(Cl)ccc2nc(-c3cc[nH]n3)ccc12>>C[Si](C)(C)CCOCn1ccc(-c2ccc3c(N)c(Cl)ccc3n2)n1 -US20040102450A1,1,COCC1NCC(C)N(Cc2ccc3c(N)ncnc3c2)C1=O.Clc1ccc2cc(CBr)ccc2c1>>COC[C@H]1C(=O)N(Cc2ccc3c(N)ncnc3c2)[C@@H](C)CN1Cc1ccc2cc(Cl)ccc2c1 -US20100075952A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCOCC1)CCC2.O=C1Cc2c(cccc2-c2cccc(F)c2F)N1>>Cc1c(C=C2C(=O)Nc3cccc(-c4cccc(F)c4F)c32)[nH]c2c1C(=O)N(CCN1CCOCC1)CCC2 -US06461390B1,1,CC(=O)NCc1cc([N+](=O)[O-])ccc1O.NC(=O)CCl>>CC(=O)NCc1cc([N+](=O)[O-])ccc1OCC(N)=O -US20140235863A1,4,NC(=S)NN=C1CCN(Cc2ccccc2)CC1.O=C(CBr)c1ccc(F)cc1>>Fc1ccc(-c2csc(NN=C3CCN(Cc4ccccc4)CC3)n2)cc1 -US20150038488A1,3,COc1cc(B(O)O)ccc1C#N.C[C@@H](Oc1nc(Cl)cc2ncn(C)c12)[C@H]1CNC(=O)C1>>COc1cc(-c2cc3ncn(C)c3c(O[C@H](C)[C@H]3CNC(=O)C3)n2)ccc1C#N -US06713462B2,7,CCOC([PH2]=O)(c1ccc([N+](=O)[O-])cc1)P(=O)(OCC)OCC>>CCOC([PH2]=O)(c1ccc(N)cc1)P(=O)(OCC)OCC -US20060111351A1,1,C[C@H]1CNC[C@@H](C)O1.Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(Br)cc2)cn1>>Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(N3C[C@H](C)O[C@H](C)C3)cc2)cn1 -US20140163110A1,1,CC(C)C=O.Nc1ccc(F)cc1>>CC(C)CNc1ccc(F)cc1 -US07671080B2,2,CC(O)CCN.N#Cc1ccc2c(c1)cc(C(=O)O)n2Cc1cccc(OC(F)(F)F)c1>>CC(O)CCNC(=O)c1cc2cc(C#N)ccc2n1Cc1cccc(OC(F)(F)F)c1 -US20090163489A1,1,CC(=O)c1ccc(S(=O)(=O)Nc2cc(Br)cnc2Cl)cc1.CN>>CNC(C)c1ccc(S(=O)(=O)Nc2cc(Br)cnc2Cl)cc1 -US20140107340A1,2,CS(=O)(=O)c1ccc(Cl)c(C(=O)O)c1.NCC(CC1CC1)c1ccc(C(F)(F)F)nc1>>CS(=O)(=O)c1ccc(Cl)c(C(=O)NCC(CC2CC2)c2ccc(C(F)(F)F)nc2)c1 -US20140200207A1,2,CN.Nc1ccc(C(=O)O)cc1Cl>>CNC(=O)c1ccc(N)c(Cl)c1 -US20100016282A1,1,BrCCCOCc1ccccc1.NCCO>>OCCNCCCOCc1ccccc1 -US06265426B1,2,CC(C)Oc1ccc(C(=O)O)cc1.NN>>CC(C)Oc1ccc(C(=O)NN)cc1 -US04654353,7,CCOC(=O)C1=C(COCC#CC(=O)OC)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl>>CCOC(=O)C1=C(COCCCC(=O)OC)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl -US08093264B2,2,COc1ccccc1NC(=O)CC(=O)O.C[Si](C)(C)CCOCn1cnc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)c1>>COc1ccccc1NC(=O)CC(=O)Nc1ccc(Oc2ccnc3cc(-c4cn(COCC[Si](C)(C)C)cn4)sc23)c(F)c1 -US20120184540A1,1,COC1=NC(C)(c2cccc(Br)c2)COC1.NCc1cccc(Cl)c1>>COC1=NC(C)(c2cccc(NCc3cccc(Cl)c3)c2)COC1 -US20150038437A1,6,CCc1cc(C(=O)OC)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2c(c1)cc(CCO[Si](C)(C)C(C)(C)C)n2C>>CCc1cc(C(=O)OC)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2c(c1)cc(CCO)n2C -US20030162795A1,1,NCCCN1CCCC1=O.O=Cc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1>>O=C1CCCN1CCCNCc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 -US07592332B2,7,CC(C)(C)c1c[nH]c(=O)c([N+](=O)[O-])c1>>CC(C)(C)c1c[nH]c(=O)c(N)c1 -US20140275006A1,2,CCOC(=O)CC(=O)NN.COc1cccc(N=C=O)c1>>CCOC(=O)CC(=O)NNC(=O)Nc1cccc(OC)c1 -US05981572,2,CS(=O)(=O)Cl.OCCc1cccc2c1CCO2>>CS(=O)(=O)OCCc1cccc2c1CCO2 -US20040259921A1,6,COC(=O)c1ccc(CCCN2C(=O)CCC2CCC(Cc2ccccc2)O[Si](C)(C)C(C)(C)C)cc1>>COC(=O)c1ccc(CCCN2C(=O)CCC2CCC(O)Cc2ccccc2)cc1 -US20040063720A1,1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2.Nc1cc(Cl)ncn1>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1cc(N)ncn1 -US06284785B1,2,Cc1ccc(S(=O)(=O)Cl)cc1.c1csc(C2CCCN2)c1>>Cc1ccc(S(=O)(=O)N2CCCC2c2cccs2)cc1 -US20150119385A1,1,COC(OC)c1nc2c(cc1Br)CCCN2.Cc1nc[nH]n1>>COC(OC)c1nc2c(cc1-n1cnc(C)n1)CCCN2 -US08461348B2,10,CCOC(=O)c1ccc(C)c(F)c1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccc(CBr)c(F)c1 -US07427631B2,1,CN1C(=O)N(CC(=O)CBr)C(=O)C1(C)C.SCc1ccccc1>>CN1C(=O)N(CC(=O)CSCc2ccccc2)C(=O)C1(C)C -US06197959B1,2,COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)N(CCN)CCC3)cc1.CS(=O)(=O)Cl>>COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)N(CCNS(C)(=O)=O)CCC3)cc1 -US08765744B2,1,CC1(C)COC2(CCC(O)(CC=O)CC2)OC1.NC1(c2ccc(Br)cc2)CC1>>CC1(C)COC2(CCC(O)(CCNC3(c4ccc(Br)cc4)CC3)CC2)OC1 -US20100216766A1,2,CS(=O)(=O)c1cc2nccc(Oc3ccc(N)cc3F)c2s1.O=C(Cc1ccccc1)N=C=S>>CS(=O)(=O)c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1 -US20100130446A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=Cc1ccc(-c2ccc(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)nc1>>CC(C)(C)OC(=O)n1c(-c2ccc(C=O)cn2)ccc1C(CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1 -US03953476,1,CI.O=C(O)c1cc(S(=O)O)c(Cl)cc1Cl>>CS(=O)(=O)c1cc(C(=O)O)c(Cl)cc1Cl -US20090233956A1,1,CN1CCNCC1.COc1cc2c(-c3cc4c(Cl)ccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(CCI)c2cc1OC>>COc1cc2c(-c3cc4c(Cl)ccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(CCN3CCN(C)CC3)c2cc1OC -US20080293706A1,2,CNC.O=C(OCc1ccccc1)N1CCC(S(=O)(=O)Cl)CC1>>CN(C)S(=O)(=O)C1CCN(C(=O)OCc2ccccc2)CC1 -US20150045368A1,3,CC1(C)OC(=O)N(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[C@H]1c1ccccc1.O=c1[nH]c2cnccc2cc1Br>>CC1(C)OC(=O)N(c2ccc(-c3cc4ccncc4[nH]c3=O)cc2)[C@H]1c1ccccc1 -US20050277630A1,1,CS(=O)(=O)OCC1CN(c2ccc3c(c2)OCCCC3=O)C(=O)O1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC1CN(c2ccc3c(c2)OCCCC3=O)C(=O)O1 -US05470878,1,C=CCCCCBr.Cn1ccc(=O)[nH]c1=O>>C=CCCCCn1c(=O)ccn(C)c1=O -US20090124618A1,1,C[C@H](c1ccccc1)N1CCO[C@@H](c2ccc(Br)cc2)C1.NC1CCCCC1>>C[C@H](c1ccccc1)N1CCO[C@@H](c2ccc(NC3CCCCC3)cc2)C1 -US20110053892A1,2,CCCOc1ccc(-c2cc(C(C(=O)OC)n3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)c(C(F)(F)F)c1.CN>>CCCOc1ccc(-c2cc(C(C(=O)NC)n3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)c(C(F)(F)F)c1 -US20080300266A1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1.Fc1ccc(Br)cn1>>CC(C)(C)OC(=O)N[C@H]1CCN(c2ccc(F)nc2)C1 -US07247654B2,1,COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2N)cc(OC)c1C.NCCBr>>COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2NCCN)cc(OC)c1C -US08124629B2,7,COC(=O)c1ccc(CS(C)(=O)=O)cc1>>CS(=O)(=O)Cc1ccc(CO)cc1 -US20120208819A1,1,Brc1cnc2[nH]nc(I)c2c1.COc1ccc(CBr)cc1>>COc1ccc(Cn2nc(I)c3cc(Br)cnc32)cc1 -US20030207865A1,2,NC1(C(=O)O)CCCCC1.O=C(Cl)OCc1ccccc1>>O=C(NC1(C(=O)O)CCCCC1)OCc1ccccc1 -US07888379B2,2,C1CC2(CCN1)OCCO2.CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)Cl)s2)s1>>CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)N3CCC4(CC3)OCCO4)s2)s1 -US06103688,5,CC(C)(C)c1ccc2c(c1)CC(C=O)C2.OCCO>>CC(C)(C)c1ccc2c(c1)CC(C1OCCO1)C2 -US20150175563A1,6,COC(=O)c1sc(N2CCOCC2)c(C#N)c1C(OC)c1ccc2ccccc2c1>>COC(c1ccc2ccccc2c1)c1c(C(=O)O)sc(N2CCOCC2)c1C#N -US20080293742A1,4,CC(=O)CCC(C)=O.Nc1ncc(Br)nc1Br>>Cc1ccc(C)n1-c1ncc(Br)nc1Br -US05990142,6,CCOC(=O)c1cc(=O)c2cccc(NC(=O)c3ccc4oc(COCc5ccccc5)cc4c3)c2o1>>O=C(Nc1cccc2c(=O)cc(C(=O)O)oc12)c1ccc2oc(COCc3ccccc3)cc2c1 -US20150266859A1,3,CC(C)C[Mg+].COC(=O)c1ccc(C=O)cc1>>COC(=O)c1ccc(C(O)CC(C)C)cc1 -US06884815B1,2,O=C(O)c1ccccc1-n1cccn1.c1ccc(CNCc2ccc3c(c2)OCO3)cc1>>O=C(c1ccccc1-n1cccn1)N(Cc1ccccc1)Cc1ccc2c(c1)OCO2 -US20090286778A1,1,Nc1ccnc(CCc2cccc(Nc3nc(Cl)ncc3Cl)c2)c1>>Clc1cnc2nc1Nc1cccc(c1)CCc1cc(ccn1)N2 -US06531600B1,2,CC(=O)OC(C)=O.CCCCn1c(=O)c2[nH]c(N)nc2n(CCCC)c1=O>>CCCCn1c(=O)c2[nH]c(NC(C)=O)nc2n(CCCC)c1=O -US04608385,2,CC(C)OC(=O)Cl.CCOc1ccc(N)cc1OCC>>CCOc1ccc(NC(=O)OC(C)C)cc1OCC -US06319939B1,2,CCC(CC)C(c1ccc(N=C=S)cc1)n1ccnc1.Nc1nc2ccccc2s1>>CCC(CC)C(c1ccc(NC(=S)Nc2nc3ccccc3s2)cc1)n1ccnc1 -US20150164876A1,6,CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCN(CCOC)CCOCCOCCOCCC(=O)OC(C)(C)C)c2)c(-c2ccc(C(=O)NCc3cccc(C(F)(F)F)c3)cn2)c1>>CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCN(CCOC)CCOCCOCCOCCC(=O)O)c2)c(-c2ccc(C(=O)NCc3cccc(C(F)(F)F)c3)cn2)c1 -US04873236,2,CCCN(CCC)CC1CCCCN1CCN.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>CCCN(CCC)CC1CCCCN1CCNC(=O)N1c2ccccc2C(=O)Nc2cccnc21 -US20110046109A1,1,CCC(N)CC.CSc1nc(Cl)c(C=O)c(Cl)n1>>CCC(CC)Nc1nc(SC)nc(Cl)c1C=O -US03989720,2,CO.Cc1ccc2c(c1)Cc1cc(C(=O)O)ccc1O2>>COC(=O)c1ccc2c(c1)Cc1cc(C)ccc1O2 -US05541203,3,Brc1ccc(Br)nc1.CC[Mg+]>>CCc1ccc(Br)cn1 -US20060235037A1,8,CN(CCN1CCC(O)CC1)C(=O)OC(C)(C)C>>CN(CCN1CCC(=O)CC1)C(=O)OC(C)(C)C -US08586580B2,1,Nc1ccc(N2CCOCC2)nc1.O=[N+]([O-])c1cccc(-c2csc3cnc(Cl)nc23)c1>>O=[N+]([O-])c1cccc(-c2csc3cnc(Nc4ccc(N5CCOCC5)nc4)nc23)c1 -US05216167,6,CCOC(=O)c1ccc(CC(=O)NC(CC(C)C)c2ccccc2N2CCCCC2)cc1OCC>>CCOc1cc(CC(=O)NC(CC(C)C)c2ccccc2N2CCCCC2)ccc1C(=O)O -US05552435,3,COC(=O)c1cccc(I)c1.C[Sn](C)(C)c1ccc2c(=O)c(Cc3ccccc3)coc2c1>>COC(=O)c1cccc(-c2ccc3c(=O)c(Cc4ccccc4)coc3c2)c1 -US08067362B2,1,CC(C)(C)OC(=O)CCCCCCCCCCCCCCBr.COC(=O)c1cc(O)cc(C(=O)OC)c1>>COC(=O)c1cc(OCCCCCCCCCCCCCCC(=O)OC(C)(C)C)cc(C(=O)OC)c1 -US04206117,6,CCOC(=O)c1cc(Cc2ccccc2)nc(C)c1OCCCN(C)C>>Cc1nc(Cc2ccccc2)cc(C(=O)O)c1OCCCN(C)C -US20110124877A1,4,C[S+](C)C.O=C1C(Cc2ccc(F)cc2)CCC12CC2>>Fc1ccc(CC2CCC3(CC3)C23CO3)cc1 -US08796278B2,1,C[C@H]1CCCN1[C@H]1CCNC1.Cc1nc(Cl)ccc1[N+](=O)[O-]>>Cc1nc(N2CC[C@H](N3CCC[C@@H]3C)C2)ccc1[N+](=O)[O-] -US20110217311A1,2,CN[C@@H]1CC[C@H](Oc2cc(F)ccc2[N+](=O)[O-])CC1.CS(=O)(=O)Cl>>CN([C@@H]1CC[C@H](Oc2cc(F)ccc2[N+](=O)[O-])CC1)S(C)(=O)=O -US20090042929A1,1,Cc1c(C(=O)CBr)sc2ccc(Cl)cc12.SCc1ccc(Cl)cc1>>Cc1c(C(=O)CSCc2ccc(Cl)cc2)sc2ccc(Cl)cc12 -US20090048258A1,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O.O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(Cl)cc(-c2ccccc2)n1>>COc1cc(-c2cc(NC(=O)CCC(=O)c3ccc4c(c3)CCO4)nc(-c3ccccc3)c2)ccc1O -US20050009903A1,3,CC(=O)Cl.CCc1ccc2ccccc2c1>>CCc1ccc2cccc(C(C)=O)c2c1 -US04585867,2,Cc1ccccc1NCCC(=O)O.O=C(Cl)Cl>>Cc1ccccc1N(CCC(=O)O)C(=O)Cl -US20060009451A1,3,Clc1c2c(nc3ccnn13)CCCC2.OB(O)c1ccc(OCc2ccccc2)cc1>>c1ccc(COc2ccc(-c3c4c(nc5ccnn35)CCCC4)cc2)cc1 -US06958329B2,1,CC(C)C[C@@H](C(=O)NC1CCc2ccccc2NC1=O)C1(C(N)=O)CC=CC1.Fc1ccccc1Oc1cccc(CBr)c1>>CC(C)CC(C(=O)NC1CCc2ccccc2N(Cc2cccc(Oc3ccccc3F)c2)C1=O)C1(C(N)=O)CC=CC1 -US20120220633A1,1,Cc1cccc([N+](=O)[O-])c1F.Nc1ccc(Cc2ccccc2)cc1>>Cc1cccc([N+](=O)[O-])c1Nc1ccc(Cc2ccccc2)cc1 -US20120157439A1,2,CCCS(=O)(=O)N(Cc1ccccc1)c1ccc(F)c(N)c1F.CCOC(=O)c1cn(C)c2c(Cl)ncnc12>>CCCS(=O)(=O)N(Cc1ccccc1)c1ccc(F)c(NC(=O)c2cn(C)c3c(Cl)ncnc23)c1F -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1cc(OCC(C)(C)O)cc(C)c1Br>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OCC(C)(C)O)cc5C)ccc(F)c43)ccc21 -US20150252038A1,2,CS(N)(=O)=O.C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)O)cc2Cl)CC1>>C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2Cl)CC1 -US20100216746A1,10,Cc1ccc(Cl)c(Oc2cc(Br)cc(C#N)c2)c1F.O=C1CCC(=O)N1Br>>N#Cc1cc(Br)cc(Oc2c(Cl)ccc(CBr)c2F)c1 -US07060700B2,2,Cc1ccc(NC(=O)c2cccc(N(C)C)c2)cc1N.O=C(O)c1ccc2ncccc2c1>>Cc1ccc(NC(=O)c2cccc(N(C)C)c2)cc1NC(=O)c1ccc2ncccc2c1 -US20140073620A1,1,NC(=O)C1(c2ccccc2CCc2nc(Cl)ncc2Cl)CC1.Nc1ccc(C(F)(F)F)nc1>>NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C(F)(F)F)nc3)ncc2Cl)CC1 -US20020137769A1,2,CNOC.O=C(O)c1cccc2ccccc12>>CON(C)C(=O)c1cccc2ccccc12 -US20150031733A1,1,N#C[S-].O=C(CBr)c1ccc(Br)cc1F>>N#CSCC(=O)c1ccc(Br)cc1F -US20090062294A1,1,CC(C)(C)OC(=O)N1CCN(Cc2cccc(O)c2)CC1.Clc1ncccn1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(Oc3ncccn3)c2)CC1 -US20120035168A1,1,Cc1cc(NC(=O)OC(C)(C)C)nc(C)c1CNC(=O)c1cn[nH]c1.Clc1ccc2ccc(CBr)nc2c1>>Cc1cc(NC(=O)OC(C)(C)C)nc(C)c1CNC(=O)c1cnn(Cc2ccc3ccc(Cl)cc3n2)c1 -US20080221114A1,2,C1CCNC1.O=C(O)C1Cc2ccccc2N1c1ncccn1>>O=C(C1Cc2ccccc2N1c1ncccn1)N1CCCC1 -US20140200197A1,2,CC(C)(C)OC(=O)N1C[C@@H](CCc2c(N)cncc2F)OC[C@@H]1COC(=O)NCC(F)(F)F.[N-]=[N+]=N[C@H](C(=O)O)[C@@H](c1ccc(F)cc1)c1cc(F)cc(F)c1>>CC(C)(C)OC(=O)N1C[C@@H](CCc2c(F)cncc2NC(=O)[C@@H](N=[N+]=[N-])[C@@H](c2ccc(F)cc2)c2cc(F)cc(F)c2)OC[C@@H]1COC(=O)NCC(F)(F)F -US20110028467A1,2,O=C(O)c1cc(Br)c(O)c(Br)c1.c1cnc2c(c1)NCCO2>>O=C(c1cc(Br)c(O)c(Br)c1)N1CCOc2ncccc21 -US06245761B1,1,ClCCCCCBr.OCc1cc(Br)ccc1F>>Fc1ccc(Br)cc1COCCCCCCl -US04659708,1,COc1cc(N)c2nccc(C)c2c1.OCCCCCCCl>>COc1cc(NCCCCCCO)c2nccc(C)c2c1 -US03941803,1,O=C(c1ccccc1Cl)c1cc(Cl)ccc1-n1ccnc1CO.O=C1NC(=O)c2ccccc21>>O=C(c1ccccc1Cl)c1cc(Cl)ccc1-n1ccnc1CN1C(=O)c2ccccc2C1=O -US08735584B2,1,Nc1ccc(NC(=O)c2ccc(F)cc2C(F)(F)F)cc1.O=c1[nH]c2nccc(Cl)c2c2ccccc12>>O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1)c1ccc(F)cc1C(F)(F)F -US08263772B2,1,C=O.COc1cc(Br)ccc1N1CCNCC1>>COc1cc(Br)ccc1N1CCN(C)CC1 -US07423159B2,2,CCOC(=O)Cc1ccc(N)cc1.Cn1ncc(/C=C/C(=O)O)c1-c1ccc(F)cc1>>CCOC(=O)Cc1ccc(NC(=O)/C=C/c2cnn(C)c2-c2ccc(F)cc2)cc1 -US08835428B2,7,CCOC(=O)c1cc(-c2cccc([N+](=O)[O-])c2)no1>>CCOC(=O)c1cc(-c2cccc(N)c2)no1 -US20090186876A1,2,CCOC(=O)c1cnc(N2CCNCC2)c(Br)c1.O=C=Nc1ccccc1>>CCOC(=O)c1cnc(N2CCN(C(=O)Nc3ccccc3)CC2)c(Br)c1 -US07544637B2,1,C[O-].N#Cc1c(N)cccc1F>>COc1cccc(N)c1C#N -US07396844B1,2,N#Cc1ccc(C(=O)Cl)cc1.N#Cc1cccc(OC[C@@H](CC(=O)OCc2ccccc2)NCc2ccccc2)c1>>N#Cc1ccc(C(=O)N(Cc2ccccc2)[C@@H](COc2cccc(C#N)c2)CC(=O)OCc2ccccc2)cc1 -US20040014802A1,1,CN(C)CCCN.O=C(CCl)Nc1n[nH]c2cc(Cl)ccc12>>CN(C)CCCNCC(=O)Nc1n[nH]c2cc(Cl)ccc12 -US05006549,6,CCOC(=O)c1oc2c(C(=O)c3ccc(Cl)cc3)cc(C(C)(C)C)c(O)c2c1C>>Cc1c(C(=O)O)oc2c(C(=O)c3ccc(Cl)cc3)cc(C(C)(C)C)c(O)c12 -US20100331293A1,3,CSc1ccc(OC(F)(F)F)cc1B(O)O.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>CSc1ccc(OC(F)(F)F)cc1-c1nc2cc(F)cc(F)c2c(Cl)c1C -US20130315874A1,4,C#CCCCc1c[nH]c(N)n1.[N-]=[N+]=NCCc1ccsc1>>Nc1nc(CCCc2cn(CCc3ccsc3)nn2)c[nH]1 -US20070105865A1,2,CN(C)CC(=O)Cl.O=[N+]([O-])c1ccc2c(c1)NCCC2>>CN(C)CC(=O)N1CCCc2ccc([N+](=O)[O-])cc21 -US20090181963A1,2,Nc1cccnc1.O=C(O)Cn1nnc2c(N3CCOCC3)nc(-c3cccc(CO)c3)nc21>>O=C(Cn1nnc2c(N3CCOCC3)nc(-c3cccc(CO)c3)nc21)Nc1cccnc1 -US08552181B2,3,CC(C)[Si](c1ncc(Br)s1)(C(C)C)C(C)C.COC(=O)[C@@H](CI)C(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1cnc([Si](C(C)C)(C(C)C)C(C)C)s1)C(=O)OC(C)(C)C -US05041567,7,CCOC(=O)c1cc(-c2ccccc2)on1>>OCc1cc(-c2ccccc2)on1 -US20100105684A1,1,CNC.COc1cccc2c1CCC(=O)C2>>COc1cccc2c1CCC(N(C)C)C2 -US05296609,1,Cc1nc(-c2ccc(C(F)(F)F)cc2)n(CC(C)C)c1C=O.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Cc1nc(-c2ccc(C(F)(F)F)cc2)n(CC(C)C)c1CN1CCN(C(c2ccccc2)c2ccccc2)CC1 -US06642389B2,1,COc1ccc(CCl)cc1.Cc1oc(-c2ccccc2)nc1CCOc1ccc(C=O)c(O)c1>>COc1ccc(COc2cc(OCCc3nc(-c4ccccc4)oc3C)ccc2C=O)cc1 -US04964895,1,CN(C)N.O=[N+]([O-])c1ccc(F)cc1F>>CN(C)Nc1cc(F)ccc1[N+](=O)[O-] -US20130059834A1,6,C[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CC(F)(F)C1>>C[C@@H](N)C(=O)N1CC(F)(F)C1 -US20080119466A1,1,CC(C)(C)OC(=O)Nc1ccc2[nH]ccc2c1.O=[N+]([O-])c1ccc(F)c(F)c1>>CC(C)(C)OC(=O)Nc1ccc2c(ccn2-c2ccc([N+](=O)[O-])cc2F)c1 -US20120295897A1,9,O=C1N(C(c2ccccc2)c2ccccc2)c2cccc(F)c2C1(O)c1cc2c(cc1O)OCCO2>>O=C1C(c2cc3c(cc2O)OCCO3)c2c(F)cccc2N1C(c1ccccc1)c1ccccc1 -US20150191466A1,7,COc1cc(CNc2ncc(I)cc2[N+](=O)[O-])ccc1OCc1ccc(C)nc1>>COc1cc(CNc2ncc(I)cc2N)ccc1OCc1ccc(C)nc1 -US20120129855A1,2,CCOC1CCNCC1.Cc1[nH]c(C)c2c(=O)[nH]nc(Cc3cccc(C(=O)O)c3)c12>>CCOC1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4c(C)[nH]c(C)c34)c2)CC1 -US04703036,2,CCN[C@H](Cc1ccccc1)C(=O)O.O=C(Cl)OCc1ccccc1>>CCN(C(=O)OCc1ccccc1)[C@H](Cc1ccccc1)C(=O)O -US09108983B2,1,C=C(C)CCl.C=CCNS(=O)(=O)c1ccc(C)cc1>>C=CCN(CC(=C)C)S(=O)(=O)c1ccc(C)cc1 -US20090281100A1,3,COc1ccc(B(O)O)cc1.O=c1[nH]c2ccc(Br)cc2c(N[C@@H]2CN3CCC2CC3)c1-c1nc2ccccc2[nH]1>>COc1ccc(-c2ccc3[nH]c(=O)c(-c4nc5ccccc5[nH]4)c(N[C@@H]4CN5CCC4CC5)c3c2)cc1 -US20100137368A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.N#Cc1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(C#N)cn2)CC1 -US20100120669A1,2,NNC(N)=S.O=C(O)COc1ccccc1Cl>>NC(=S)NNC(=O)COc1ccccc1Cl -US20100121048A1,6,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1CCO>>CC(C)(C)OC(=O)N1CCNC[C@H]1CCO -US20040198982A1,2,CC(C)CC(OCc1ccc(Br)cc1)C(=O)O.N#CCN>>CC(C)CC(OCc1ccc(Br)cc1)C(=O)NCC#N -US20130252941A1,7,Cc1cc(Nc2ncc(F)c3nn(-c4c(Cl)cc(C=O)cc4Cl)cc23)ncn1>>Cc1cc(Nc2ncc(F)c3nn(-c4c(Cl)cc(CO)cc4Cl)cc23)ncn1 -US20100004271A1,2,CC(C)CC(=O)Cl.COC(=O)Cc1cc(Cl)c(Oc2ccc(N)c(Br)c2)c(Cl)c1>>COC(=O)Cc1cc(Cl)c(Oc2ccc(NC(=O)CC(C)C)c(Br)c2)c(Cl)c1 -US09045486B2,6,CC(C)(C)OC(=O)c1nc(CC2(c3cccc(Cl)c3)CCCC2)nc(O)c1OCc1ccccc1>>O=C(O)c1nc(CC2(c3cccc(Cl)c3)CCCC2)nc(O)c1OCc1ccccc1 -US05424333,2,CC(C)(C)N(N)C(=O)c1ccc(Cl)cc1.O=C(O)c1cncc(Br)c1>>CC(C)(C)N(NC(=O)c1cncc(Br)c1)C(=O)c1ccc(Cl)cc1 -US07531553B2,1,CC(C)N1CCNCC1.O=[N+]([O-])c1ccc(Br)c(OC(F)F)c1>>CC(C)N1CCN(c2ccc([N+](=O)[O-])cc2OC(F)F)CC1 -US04013692,1,CC(=O)OCCl.O=C(O)Cc1oc2cccc-2cc1-c1ccccc1>>CC(=O)OCOC(=O)Cc1oc2cccc-2cc1-c1ccccc1 -US20130079303A1,6,COc1ccc(Nc2ncc(C3OCCO3)cc2-c2nc(C)nc3c2ncn3C2CCCCO2)cn1>>COc1ccc(Nc2ncc(C=O)cc2-c2nc(C)nc3c2ncn3C2CCCCO2)cn1 -US08143271B2,3,Brc1cnc2[nH]ccc2c1.CC(=O)Oc1cccc(C(=O)Cl)c1C>>CC(=O)Oc1cccc(C(=O)c2c[nH]c3ncc(Br)cc23)c1C -US20150105366A1,1,C[O-].FC(F)(F)c1ccc(Cc2c(Cl)nc3ccc(Br)cc3c2Cl)cc1>>COc1nc2ccc(Br)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 -US20120214784A1,1,Cc1n[nH]cc1C=O.N#Cc1cccc(F)c1F>>Cc1nn(-c2c(F)cccc2C#N)cc1C=O -US20100278833A1,6,C[C@@H](Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F>>C[C@@H](Oc1cc(-n2cnc3cnc(CO)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F -US20080269210A1,3,Cc1c(I)sc2c(N3CCOCC3)nc(Cl)nc12.O=Cc1cc(B(O)O)cs1>>Cc1c(-c2csc(C=O)c2)sc2c(N3CCOCC3)nc(Cl)nc12 -US20020165241A1,1,Nc1cnccn1.O=CC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(CNc2cnccn2)CC1 -US05708168,6,COc1cc(=O)c2c([nH]c1=O)CCCC2>>O=c1cc(O)c(=O)[nH]c2c1CCCC2 -US20070049618A1,2,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(O)Cc1ccsc1>>O=C(Cc1ccsc1)NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O -US06143779,2,COc1cccc(C=C2Oc3cc(O)ccc3C2=O)c1.O=C(Cl)c1ccccc1>>COc1cccc(C=C2Oc3cc(OC(=O)c4ccccc4)ccc3C2=O)c1 -US20110288090A1,9,CC(C)(C)OC(=O)NCc1ccc(-c2nc3ccnc(Cl)c3cc2-c2ccccc2)cc1.N>>CC(C)(C)OC(=O)NCc1ccc(-c2nc3ccnc(N)c3cc2-c2ccccc2)cc1 -US08735584B2,1,N#Cc1ccccc1CBr.Nc1ccc2c(=O)[nH]c3ncccc3c2c1>>N#Cc1ccccc1CNc1ccc2c(=O)[nH]c3ncccc3c2c1 -US07906522B2,7,O=[N+]([O-])c1ccnc(N2CCCC2)c1>>Nc1ccnc(N2CCCC2)c1 -US04568695,8,Nc1c(CCO)cccc1C(O)c1ccccc1>>Nc1c(CCO)cccc1C(=O)c1ccccc1 -US20080113961A1,7,C#Cc1csc(C=O)c1>>C#Cc1csc(CO)c1 -US05885999,2,CC(C)(C)OC(=O)N1CCC(CNc2ccccc2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(CN(c2ccccc2)S(C)(=O)=O)CC1 -US20070060618A1,3,Cc1nc(C#Cc2cncc(Br)c2)cs1.OB(O)c1ccc(Cl)nc1>>Cc1nc(C#Cc2cncc(-c3ccc(Cl)nc3)c2)cs1 -US05061720,6,CCOC(=O)c1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1>>CCOC(=O)c1ccc(OCCCN)cc1 -US07109339B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1cccc2c3c([nH]c12)CCNC3>>CC(C)(C)OC(=O)N1CCc2[nH]c3c(I)cccc3c2C1 -US20110257208A1,1,Brc1cnc2ccccc2c1.CC(C)(C)OC(=O)N1Cc2ncnc(N)c2C1>>CC(C)(C)OC(=O)N1Cc2ncnc(Nc3cnc4ccccc4c3)c2C1 -US20120208819A1,3,CC1(C)OB(c2ccc(CN)cc2)OC1(C)C.Cc1cc(Br)cnc1N>>Cc1cc(-c2ccc(CN)cc2)cnc1N -US20110046108A1,2,CNC.O=C(Cl)c1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1>>CN(C)C(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 -US20100168185A1,2,CC(=O)Cl.CCc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CC3)c2)s1>>CCc1nc(-c2ccc(F)cc2)c(-c2ccnc(N(C(C)=O)C3CC3)c2)s1 -US20150238473A1,7,CC(C)(C)c1ccc(C(=O)CCl)cc1>>CC(C)(C)c1ccc(CCCl)cc1 -US20140378455A1,6,CCOC(=O)c1ccc(CN2CCC(CNC(=O)c3n[nH]c4ccc(Br)cc34)CC2)o1>>O=C(O)c1ccc(CN2CCC(CNC(=O)c3n[nH]c4ccc(Br)cc34)CC2)o1 -US20020087002A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(CO[C@H]2CNC[C@@H](OC[C@H](O)CO)[C@@H]2c2ccc(OCCCOc3ccccc3[N+](=O)[O-])cc2)cc2ccccc12>>COc1cc(CO[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H](OC[C@H](O)CO)[C@@H]2c2ccc(OCCCOc3ccccc3[N+](=O)[O-])cc2)cc2ccccc12 -US20030232860A1,2,CO.COc1nc(N)c(C#N)c(-c2cccc(C(=O)O)c2)c1C#N>>COC(=O)c1cccc(-c2c(C#N)c(N)nc(OC)c2C#N)c1 -US20140315883A1,6,CC(=O)N1C[C@H](O)C[C@@H]1c1nc(-c2ccc(N(C(=O)OCc3ccccc3)C(C)C)cc2)c2cnc3[nH]cc(C)c3n12>>CC(=O)N1C[C@H](O)C[C@@H]1c1nc(-c2ccc(NC(C)C)cc2)c2cnc3[nH]cc(C)c3n12 -US20110212956A1,2,O=C(O)c1cc2ncc(Cl)cn2n1.O=[N+]([O-])c1cccc2c1CCNC2>>O=C(c1cc2ncc(Cl)cn2n1)N1CCc2c(cccc2[N+](=O)[O-])C1 -US20110112106A1,1,Brc1ccc2c(ccc3nnnn32)c1.CCCCC(CC)COC(=O)CCS>>CCCCC(CC)COC(=O)CCSc1ccc2c(ccc3nnnn32)c1 -US05563147,3,CN(C)C=O.Cc1ccc2cc[nH]c2c1>>Cc1ccc2c(C=O)c[nH]c2c1 -US20140094474A1,6,CCOC(=O)c1cc(-c2ccn[nH]2)n[nH]1>>O=C(O)c1cc(-c2ccn[nH]2)n[nH]1 -US20030166658A1,1,CC(=O)c1ccncn1.NNc1nc2ccccc2[nH]1>>CC(=NNc1nc2ccccc2[nH]1)c1ccncn1 -US20070082908A1,9,CCOC(=O)c1c(Cc2ccccc2)c(N)nn1Cc1ccc(OC)cc1.ICI>>CCOC(=O)c1c(Cc2ccccc2)c(I)nn1Cc1ccc(OC)cc1 -US20100249124A1,3,Clc1cc(Br)ccc1CBr.Cn1c(=O)oc2cc(C(=O)Cl)ccc21>>Cn1c(=O)oc2cc(C(=O)Cc3ccc(Br)cc3Cl)ccc21 -US20030109527A1,2,Nc1ccc(Cl)c(S(=O)(=O)N2CCC2)c1O.O=C=Nc1ccccc1Br>>O=C(Nc1ccccc1Br)Nc1ccc(Cl)c(S(=O)(=O)N2CCC2)c1O -US07645769B2,2,Cn1cc(-c2c[nH]c3ncc(N)cc23)cn1.O=C(Cl)c1ccc(F)cc1>>Cn1cc(-c2c[nH]c3ncc(NC(=O)c4ccc(F)cc4)cc23)cn1 -US20080058383A1,1,CC(C)(N)CO.O=[N+]([O-])c1ccc(F)cc1C(F)(F)F>>CC(C)(CO)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1 -US07297700B2,6,O=C(CC12CC3CC(CC(C3)C1)C2)Nc1ncnc2c1CCN(Cc1ccccc1)C2>>O=C(CC12CC3CC(CC(C3)C1)C2)Nc1ncnc2c1CCNC2 -US20060035938A1,7,CSc1ccc(C=O)cc1Br>>CSc1ccc(CO)cc1Br -US07666888B2,2,Cc1ccc(-c2oncc2C(=O)O)cc1.O=C1CNCCN1>>Cc1ccc(-c2oncc2C(=O)N2CCNC(=O)C2)cc1 -US20140315889A1,1,CCOC(=O)CCCCCCBr.Cc1cc2c([nH]1)CC(C)(C)CC2=O>>CCOC(=O)CCCCCCn1c(C)cc2c1CC(C)(C)CC2=O -US20130029991A1,2,COC(=O)[C@@H](N)CC(N)=O.O=C(O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1>>COC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1 -US20140243336A1,1,COc1ccc(CN)c(OC)c1.Cc1cc(C(C)(C)O)cc(Cl)n1>>COc1ccc(CNc2cc(C(C)(C)O)cc(C)n2)c(OC)c1 -US20120289522A1,3,CCOC(=O)C(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cc1noc(-c2ccc(Br)cc2)c1CC(F)(F)CCc1ccccc1>>CCOC(=O)C(C)c1ccc(-c2ccc(-c3onc(C)c3CC(F)(F)CCc3ccccc3)cc2)cc1 -US08729084B2,6,CC(C)(C)OC(=O)N1CCC(O)(C2Cc3cccc(F)c3O2)CC1>>OC1(C2Cc3cccc(F)c3O2)CCNCC1 -US20100286390A1,1,CCN(CC)c1ccc(C(=O)Cn2ncc(Cl)c(Cl)c2=O)cc1.NC12CC3CC(CC1C3)C2>>CCN(CC)c1ccc(C(=O)Cn2ncc(NC34CC5CC(CC3C5)C4)c(Cl)c2=O)cc1 -US20140094465A1,3,Brc1cnc(Br)s1.O=C(O)c1ccc(B(O)O)s1>>O=C(O)c1ccc(-c2ncc(Br)s2)s1 -US04764525,1,CC(C)Br.COC(=O)c1ccc(OC)cc1O>>COC(=O)c1ccc(OC)cc1OC(C)C -US20100160308A1,6,COC(OC)c1ccc([N+](=O)[O-])c(Nc2nc(-c3ccc(C(F)(F)F)cc3)c(C(N)=O)s2)c1>>NC(=O)c1sc(Nc2cc(C=O)ccc2[N+](=O)[O-])nc1-c1ccc(C(F)(F)F)cc1 -US20100144745A1,2,C[Si](C)(C)CCOCn1cc(Cl)c2nc(N)cnc21.O=C=NC1CCCCC1>>C[Si](C)(C)CCOCn1cc(Cl)c2nc(NC(=O)NC3CCCCC3)cnc21 -US08354444B2,6,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)s1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)s2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20140228361A1,6,CC(C)(C)OC(=O)N1CCC2OCCOC2C1>>C1CC2OCCOC2CN1 -US05547962,6,Cc1c(N2C[C@@H](NC(=O)C(F)(F)F)C(C)(C)C2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12>>Cc1c(N2C[C@@H](N)C(C)(C)C2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12 -US20040039029A1,6,CC(C)(C)OC(=O)N1CCCCC1CNc1cccc(NC(=O)Nc2csc(-c3ccncc3)n2)n1>>O=C(Nc1cccc(NCC2CCCCN2)n1)Nc1csc(-c2ccncc2)n1 -US08242280B2,6,CCOC(=O)C(c1cccc(Br)c1)N(C)C>>CN(C)C(C(=O)O)c1cccc(Br)c1 -US20130296312A1,9,BrC(Br)(Br)Br.CN(c1ccccc1CO)S(C)(=O)=O>>CN(c1ccccc1CBr)S(C)(=O)=O -US20080214616A1,2,CC(C)(C)OC(=O)N1[C@H](Cc2ccccc2F)[C@H](Cc2ncccc2C(=O)O)OC1(C)C.NC1CC1>>CC(C)(C)OC(=O)N1[C@H](Cc2ccccc2F)[C@H](Cc2ncccc2C(=O)NC2CC2)OC1(C)C -US07732446B1,6,COc1cc(OC)c2c(CNC(=O)OC(C)(C)C)ncc(C(=O)N(C)CCc3ccccn3)c2c1>>COc1cc(OC)c2c(CN)ncc(C(=O)N(C)CCc3ccccn3)c2c1 -US20040162435A1,9,CN1C(=O)CC[C@@H]1CBr.[C-]#N>>CN1C(=O)CC[C@@H]1CC#N -US08288419B2,2,CC(F)(F)c1ccc(Cn2cc(N)cn2)o1.COc1cccc(/C=C/C(=O)O)c1OC>>COc1cccc(/C=C/C(=O)Nc2cnn(Cc3ccc(C(C)(F)F)o3)c2)c1OC -US06638929B2,1,COc1cc(N)c(C)cc1Cl.COc1cc2cc3c(Cl)c(C#N)cnc3cc2cc1OCCCl>>COc1cc(Nc2c(C#N)cnc3cc4cc(OCCCl)c(OC)cc4cc23)c(C)cc1Cl -US05637605,1,BrCc1ccc(Br)cc1.c1nc[nH]n1>>Brc1ccc(Cn2cncn2)cc1 -US08193176B2,1,C[C@@H]1CCCN1.ClCCOc1ccc(I)cc1>>C[C@@H]1CCCN1CCOc1ccc(I)cc1 -US05202344,1,COCC1CCCN1N.O=C1CCN(c2ccccc2)C1=O>>COCC1CCCN1N=C1CCN(c2ccccc2)C1=O -US05622976,2,COc1cccc(C(=O)Cl)c1.OCCC1CCNCC1>>COc1cccc(C(=O)N2CCC(CCO)CC2)c1 -US20040167119A1,7,N#Cc1c[nH]c2ccccc12>>NCc1c[nH]c2ccccc12 -US20130245278A1,1,CC(C)CBr.CCOC(=O)c1sc(-c2ccc(O)c(C#N)c2)nc1C>>CCOC(=O)c1sc(-c2ccc(OCC(C)C)c(C#N)c2)nc1C -US08791090B2,1,CC(=O)N1c2ccccc2C(=O)CC1C.Nc1ccc2ocnc2c1>>CC(=O)N1c2ccccc2C(=Nc2ccc3ocnc3c2)CC1C -US20090318431A1,2,CN.COC(=O)[C@H]1CN(c2ccc3c(c2)CCOC(=O)N3C)C(=O)O1>>CNC(=O)[C@H]1CN(c2ccc3c(c2)CCOC(=O)N3C)C(=O)O1 -US20030055064A1,1,CC(=O)NC(C)(C)c1ccc(CCl)cc1.c1csc(N2CCNCC2)n1>>CC(=O)NC(C)(C)c1ccc(CN2CCN(c3nccs3)CC2)cc1 -US20150080438A1,1,CNCCCSCCCC(F)(F)C(F)(F)F.CS(=O)(=O)c1ccc(C2=C(CCCCCBr)c3ccc(O)cc3CCC2)cc1>>CN(CCCCCC1=C(c2ccc(S(C)(=O)=O)cc2)CCCc2cc(O)ccc21)CCCSCCCC(F)(F)C(F)(F)F -US05605901,2,CCCC(=O)Cl.NC1Cc2ccc(C3=NNC(=O)CC3)cc2C1>>CCCC(=O)NC1Cc2ccc(C3=NNC(=O)CC3)cc2C1 -US20100216746A1,2,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1.O=C(Cl)c1cc2c(Cl)cc(Cl)cc2[nH]1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3cc4c(Cl)cc(Cl)cc4[nH]3)c2F)c1 -US08247429B2,7,Cn1cc2c3c(c(Cl)cc2n1)CCC3=CC#N>>Cn1cc2c3c(c(Cl)cc2n1)CCC3=CCN -US20010014683A1,9,ClC(Cl)(Cl)Cl.O[C@@H]1CCN(Cc2ccccc2)C1>>Cl[C@H]1CCN(Cc2ccccc2)C1 -US20110105436A1,2,Nc1nc(-c2ccncc2)cs1.O=C(Cl)c1ccccc1>>O=C(Nc1nc(-c2ccncc2)cs1)c1ccccc1 -US07304082B2,1,BrCc1ccccc1.Sc1nc(Nc2ccccc2)n[nH]1>>c1ccc(CSc2nc(Nc3ccccc3)n[nH]2)cc1 -US06211199B1,1,COc1cc(C(=O)N2CCC(CCOS(C)(=O)=O)(c3ccccc3)C2)cc(OC)c1OC.Fc1ccc(Cn2c(NC3CCNCC3)nc3ccccc32)cc1>>COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5n4Cc4ccc(F)cc4)CC3)(c3ccccc3)C2)cc(OC)c1OC -US20110124634A1,1,COC(=O)CN.COc1c(C)cnc(C=O)c1C>>COC(=O)CNCc1ncc(C)c(OC)c1C -US08748434B2,6,Cc1ccccc1-c1ncncc1N(C)C(=O)OC(C)(C)C>>CNc1cncnc1-c1ccccc1C -US20100075998A1,6,CCOC(=O)c1cn(C)c2c1CCc1cnc(N)nc1-2>>Cn1cc(C(=O)O)c2c1-c1nc(N)ncc1CC2 -US20120077814A1,1,O=C(O)c1ccccc1.O[C@@H]1C[C@H](c2ccc3c(N[C@H]4CCc5ccccc54)ncnn23)C=C1COCc1ccccc1>>O=C(O[C@H]1C[C@H](c2ccc3c(N[C@H]4CCc5ccccc54)ncnn23)C=C1COCc1ccccc1)c1ccccc1 -US20130085277A1,9,CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1>>CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O -US20110251178A1,1,COC(=O)c1cc(-c2ccc(F)cc2)n[nH]1.ClCCBr>>COC(=O)c1cc(-c2ccc(F)cc2)nn1CCCl -US20100105682A1,8,O=C([C@@H]1C[C@H]1CO)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>O=C[C@@H]1C[C@H]1C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1 -US20100256356A1,1,CN(C)C1CCNCC1.COc1ccc(Cn2nc(I)c3c(Oc4ccc(N)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(N3CCC(N(C)C)CC3)c3c(Oc4ccc(N)cc4F)ccnc32)cc1 -US20110319380A1,6,COC(=O)c1ccc2c(=O)[nH]c(CC(C)C)nc2c1>>CC(C)Cc1nc2cc(C(=O)O)ccc2c(=O)[nH]1 -US08436008B2,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CS(=O)(=O)OCC1CCCC1>>CC1(C)OB(c2cnn(CC3CCCC3)c2)OC1(C)C -US08173813B2,7,CN(C)CCN1C(=O)CCc2cc([N+](=O)[O-])cc(F)c21>>CN(C)CCN1CCCc2cc([N+](=O)[O-])cc(F)c21 -US07348324B2,1,ClCCCBr.O=CNc1ccc(Cl)c(Cl)c1>>O=CN(CCCCl)c1ccc(Cl)c(Cl)c1 -US20110136801A1,1,CI.O=Cc1cccc(O)c1O>>COc1c(O)cccc1C=O -US04845210,6,CC(=O)O[C@@H]1NC(=O)[C@H]1C(C)O[Si](C)(C)C(C)(C)C>>CC(=O)O[C@@H]1NC(=O)[C@H]1C(C)O -US20150266879A1,2,C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C.N[C@H](C(=O)N1c2ncccc2CC1C(=O)Nc1c(F)cccc1F)C1CCOCC1>>C[C@@H](C(=O)N[C@H](C(=O)N1c2ncccc2CC1C(=O)Nc1c(F)cccc1F)C1CCOCC1)N(C)C(=O)OC(C)(C)C -US20090156642A1,1,CN(Cc1cc(-c2cccnc2F)c(Br)s1)C(=O)OC(C)(C)C.COc1cccc(S)c1>>COc1cccc(Sc2sc(CN(C)C(=O)OC(C)(C)C)cc2-c2cccnc2F)c1 -US20040110754A1,1,C1COCCN1.C=Cc1ccc(F)c(Br)c1>>C=Cc1ccc(F)c(N2CCOCC2)c1 -US20140200216A1,6,C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2ccncc2NC(=O)c2nc3cc(N4CCOCC4)ccc3cc2NC(=O)OCc2ccccc2)C1>>C[C@@H]1C[C@H](N)CN(c2ccncc2NC(=O)c2nc3cc(N4CCOCC4)ccc3cc2NC(=O)OCc2ccccc2)C1 -US20040209866A1,2,CCC(=O)O.Cc1cc(N2CCNCC2)nc2c1c(=O)cc(Nc1ccccc1)n2-c1ccccc1>>CCC(=O)N1CCN(c2cc(C)c3c(=O)cc(Nc4ccccc4)n(-c4ccccc4)c3n2)CC1 -US20070155779A1,1,OCc1nc2ccccc2n1CF.Oc1ccc(-c2nn(CC(F)(F)F)cc2-c2ccncc2)cc1>>FCn1c(COc2ccc(-c3nn(CC(F)(F)F)cc3-c3ccncc3)cc2)nc2ccccc21 -US05814653,2,CN(C)C1CCc2[nH]c3ccc(N)cc3c2C1.O=C(Cl)Cc1ccccc1>>CN(C)C1CCc2[nH]c3ccc(NC(=O)Cc4ccccc4)cc3c2C1 -US05128335,3,Brc1cccnc1.OB(O)c1cccc(Br)c1>>Brc1cccc(-c2cccnc2)c1 -US08124610B2,1,CC(C)(C)n1nc(Cc2ccc(Cl)cc2)cc1N.O=S(=O)(Nc1nccs1)c1ccc(I)cc1>>CC(C)(C)n1nc(Cc2ccc(Cl)cc2)cc1Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 -US08143424B2,7,Cc1cccc2ccc(=O)oc12>>Cc1cccc2c1OC(=O)CC2 -US20150126522A1,6,COC(=O)c1cc(Cl)cc(-c2ccnn2C)c1Cl>>Cn1nccc1-c1cc(Cl)cc(C(=O)O)c1Cl -US20040073025A1,2,O=C(O)C1(O)c2ccccc2-c2ccccc21.O=C(OCc1ccccc1)[C@@H]1CCCN1>>O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)C1(O)c2ccccc2-c2ccccc21 -US20120202794A1,3,Cc1ccc(C=CCO)cc1.ICI>>Cc1ccc(C2CC2CO)cc1 -US05576335,2,CCCCCCCN=C=O.Nc1ccncc1N>>CCCCCCCNC(=O)Nc1cnccc1N -US20130158075A1,6,COC(=O)C1CCC(c2ncc(-c3ccc(NC(=O)Nc4ccc(Oc5ccccc5)cc4)cc3)s2)CC1>>O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc(-c2cnc(C3CCC(C(=O)O)CC3)s2)cc1 -US05378728,2,CC(C)(C)C(=O)c1ccc(C(=O)Cl)cc1.CC(C)(C)C(=O)c1ccc(C(N)=O)cc1>>CC(C)(C)C(=O)c1ccc(C(=O)NC(=O)c2ccc(C(=O)C(C)(C)C)cc2)cc1 -US20120316161A1,6,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(C)cc1N>>CCCC(C(=O)O)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(C)cc1N -US20070275968A1,3,Cc1cccc(-c2[nH]c(C(C)C)nc2-c2cccc(Br)c2)n1.OB(O)c1ccoc1>>Cc1cccc(-c2[nH]c(C(C)C)nc2-c2cccc(-c3ccoc3)c2)n1 -US20070037812A1,1,BrCc1ccccc1.Cc1cc(O)cc(O)c1>>Cc1cc(O)cc(OCc2ccccc2)c1 -US05281620,7,Cc1ccc(C(=O)O)c(OCc2ccccc2)c1>>Cc1ccc(CO)c(OCc2ccccc2)c1 -US20110237573A1,2,Nc1ccc(-c2cnccn2)cn1.O=C(O)Cc1ccc(-c2ccnc(C(F)F)c2)cc1>>O=C(Cc1ccc(-c2ccnc(C(F)F)c2)cc1)Nc1ccc(-c2cnccn2)cn1 -US07060834B2,1,CC(C)(C)CN.Oc1cc(O)c2ccccc2n1>>CC(C)(C)CNc1cc(O)nc2ccccc12 -US08618094B2,6,CC(C)(C)OC(=O)N[C@@]12CC=CC[C@H]1CN(C(=O)OCc1ccccc1)C2>>CC(C)(C)OC(=O)N[C@@]12CC=CC[C@H]1CNC2 -US20120142659A1,2,CN[C@H](CN1CC(O)C1)C1CCC1.N#Cc1ccc(C(=O)O)cc1>>CN(C(=O)c1ccc(C#N)cc1)[C@H](CN1CC(O)C1)C1CCC1 -US07956075B2,2,CCCCN=C=O.NCCc1nc(-c2ccc(-c3ccccc3)cc2)c[nH]1>>CCCCNC(=O)NCCc1nc(-c2ccc(-c3ccccc3)cc2)c[nH]1 -US20110237791A1,1,CCc1ccc(/C(=C/C2CCCC2)c2ccc(O)c(Cl)c2)nc1OC.CI>>CCc1ccc(/C(=C/C2CCCC2)c2ccc(OC)c(Cl)c2)nc1OC -US20120245139A1,3,Clc1nc(Cl)c2ccccc2n1.OB(O)c1ccc2[nH]ccc2c1>>Clc1nc(-c2ccc3[nH]ccc3c2)c2ccccc2n1 -US20110124875A1,2,COC(=O)Cl.N#Cc1cc(Cl)ccc1N>>COC(=O)Nc1ccc(Cl)cc1C#N -US07947714B2,2,CCS(=O)(=O)N1CCC(CN)(CC2CCCO2)CC1.O=C(O)c1ccc(C(F)(F)F)cc1Cl>>CCS(=O)(=O)N1CCC(CNC(=O)c2ccc(C(F)(F)F)cc2Cl)(CC2CCCO2)CC1 -US20150152108A1,3,Cc1cncc(B(O)O)c1.O=C(Nc1cnccn1)N1c2nc(Cl)ccc2N2CC[C@H]1C2>>Cc1cncc(-c2ccc3c(n2)N(C(=O)Nc2cnccn2)[C@H]2CCN3C2)c1 -US20120148603A1,1,CC(=O)c1cccc(Br)c1.CC(C)(C)[S@](N)=O>>CC(=N[S@](=O)C(C)(C)C)c1cccc(Br)c1 -US07312225B2,7,O=C(NCCCNc1nc(Cl)ncc1Br)Nc1cccc([N+](=O)[O-])c1>>Nc1cccc(NC(=O)NCCCNc2nc(Cl)ncc2Br)c1 -US20080275027A1,1,O=C(OCc1ccccc1)N1CCN(c2ccc(OC3CCNCC3)cc2)C(=O)C1.O=C1CCCC1>>O=C(OCc1ccccc1)N1CCN(c2ccc(OC3CCN(C4CCCC4)CC3)cc2)C(=O)C1 -US20140235628A1,2,N#Cc1cc(CCC2(O)CC[NH2+]CC2)ccc1F.O=C(O)Cc1ccc([N+](=O)[O-])cc1>>N#Cc1cc(CCC2(O)CCN(C(=O)Cc3ccc([N+](=O)[O-])cc3)CC2)ccc1F -US07119102B2,1,C1CC2(CCN1)OCCO2.CS(=O)c1cc(OS(=O)(=O)C(F)(F)F)nc2sc(C(N)=O)c(N)c12>>CS(=O)c1cc(N2CCC3(CC2)OCCO3)nc2sc(C(N)=O)c(N)c12 -US20140200206A1,1,COc1cc(C(=O)N[C@H](C)COS(C)(=O)=O)ccc1[N+](=O)[O-]>>COc1cc(C(=O)N2CC2C)ccc1[N+](=O)[O-] -US20040138462A1,5,CC(C)(N)Cc1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(Cc1ccccc1)NC(=O)C(F)(F)F -US20080318945A1,2,CC(C)(C)OC(=O)NCC(=O)N1CCNCC1.CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)O>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(C(=O)CNC(=O)OC(C)(C)C)CC1 -US04329518,10,Cc1c(F)ccc(-c2ccccc2)c1F.O=C1CCC(=O)N1Br>>Fc1ccc(-c2ccccc2)c(F)c1CBr -US20090082358A1,7,CCOC(=O)N1C=Cc2cccnc2C1c1ccc(F)cc1>>CCOC(=O)N1CCc2cccnc2C1c1ccc(F)cc1 -US06756374B2,1,CN1CCNCC1.O=[N+]([O-])c1ccc(F)c(F)c1>>CN1CCN(c2ccc([N+](=O)[O-])cc2F)CC1 -US20100137603A1,6,Cc1cc(C2OCCO2)c(C)cc1NC(=O)CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1>>Cc1cc(NC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(C)cc1C=O -US20090281311A1,3,Brc1ccc(-c2ccncc2)nc1.CC(C)(C)c1ccc(-c2nc(-c3ccc(Br)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1>>CC(C)(C)c1ccc(-c2nc(-c3ccc(-c4ccc(-c5ccncc5)nc4)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1 -US08314117B2,7,CC(C)[Si](O[C@@H]1CC[C@@H](c2cc(F)cc(F)c2)C(=O)c2cccnc21)(C(C)C)C(C)C>>CC(C)[Si](O[C@@H]1CC[C@@H](c2cc(F)cc(F)c2)[C@H](O)c2cccnc21)(C(C)C)C(C)C -US07138413B1,1,BrCCCBr.O=C(c1ccc(O)cc1)C1CC1>>O=C(c1ccc(OCCCBr)cc1)C1CC1 -US20090099205A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=Cc1ccsc1>>CC(C)(C)OC(=O)N1CCC(NCc2ccsc2)CC1 -US20080300242A1,7,CCCN1CCN(c2ccc([N+](=O)[O-])c(OC)c2)CC1>>CCCN1CCN(c2ccc(N)c(OC)c2)CC1 -US07279580B2,3,CC(C)(O)c1ccn2c(-c3ccc(F)c(Cl)c3)cnc2c1F.OB(O)c1ccc(Cl)cc1Cl>>CC(C)(O)c1ccn2c(-c3ccc(F)c(-c4ccc(Cl)cc4Cl)c3)cnc2c1F -US20080051399A1,6,CC(C)N(C[C@@H](C(=O)N1CCN(c2ncnc3c2[C@H](C)C[C@H]3O)CC1)c1ccc(Cl)cc1)C(=O)OC(C)(C)C>>CC(C)NC[C@@H](C(=O)N1CCN(c2ncnc3c2[C@H](C)C[C@H]3O)CC1)c1ccc(Cl)cc1 -US20100022529A1,6,Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cnn(C(=O)OC(C)(C)C)c3)c(F)c2)c(=O)n1-c1ccc(F)cc1>>Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1 -US20100022529A1,6,Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cnn(C(=O)OC(C)(C)C)c3)c(F)c2)c(=O)n1-c1ccc(F)cc1>>Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1 -US20150045356A1,2,CCCCCCCCCCCC(=O)Cl.O=C1CCc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2N1>>CCCCCCCCCCCC(=O)N1C(=O)CCc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc21 -US20090292014A1,6,CCOC(=O)c1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(-c3cccc(C)c3)ccc12>>Cc1cccc(-c2ccc3c(C(=O)O)c(C(=O)c4ccc(Cl)cc4Cl)oc3c2)c1 -US08119661B2,1,CC(C)(C)OC(=O)N1CCC(C)(N2CCC(=O)CC2)CC1.N[C@H]1CCCC[C@@H]1N>>CC(C)(C)OC(=O)N1CCC(C)(N2CCC(N[C@H]3CCCC[C@@H]3N)CC2)CC1 -US20080181866A1,2,N#Cc1cccc([C@@H]2NC(C(=O)O)CS2)c1.O=C(Cl)OCc1ccccc1>>N#Cc1cccc([C@H]2SCC(C(=O)O)N2C(=O)OCc2ccccc2)c1 -US20050277670A1,1,CC(C)(C)OC(=O)N1CCC(C(O)c2ccc(Br)cc2)CC1.Oc1ccccc1>>CC(C)(C)OC(=O)N1CCC(C(Oc2ccccc2)c2ccc(Br)cc2)CC1 -US20140329871A1,6,CCOC(=O)c1c(-c2ccc(Br)cc2)ncn1C>>Cn1cnc(-c2ccc(Br)cc2)c1C(=O)O -US06432950B1,1,O=[N+]([O-])c1cc2c(NCc3ccc4c(c3)OCO4)nc(Cl)nc2s1.c1c[nH]cn1>>O=[N+]([O-])c1cc2c(NCc3ccc4c(c3)OCO4)nc(-n3ccnc3)nc2s1 -US04894385,6,COC(=O)c1ccc(SC(Cn2ccnc2)c2cc(OC)c(OC)c(OC)c2)cc1>>COc1cc(C(Cn2ccnc2)Sc2ccc(C(=O)O)cc2)cc(OC)c1OC -US20070207175A1,6,CCCCOc1cc(CCC(=O)OC)ccc1-c1cccc(CN(C)C(=O)c2ccc(OC)cc2)c1>>CCCCOc1cc(CCC(=O)O)ccc1-c1cccc(CN(C)C(=O)c2ccc(OC)cc2)c1 -US07910595B2,2,COc1ccc(Sc2ccc(C(=O)Cl)cc2Nc2ncnc3nc(C(C)C)ccc23)cc1.COc1cccc(N)c1>>COc1ccc(Sc2ccc(C(=O)Nc3cccc(OC)c3)cc2Nc2ncnc3nc(C(C)C)ccc23)cc1 -US20110112103A1,3,O=[N+]([O-])c1ccc(Br)nc1.OB(O)c1ccc(Br)cc1>>O=[N+]([O-])c1ccc(-c2ccc(Br)cc2)nc1 -US20140249133A1,8,CCOc1cc(F)c(Cn2nc(-c3ncc(OCCSC)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1.O=C(OO)c1ccccc1Cl>>CCOc1cc(F)c(Cn2nc(-c3ncc(OCCS(C)=O)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1 -US06809092B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H]1CCCC[C@H]1CO>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1CO -US20110135671A1,1,CC(C)CN1CCNCC1.CCCCNc1nc(N)c2nc(OC)n(CCCCl)c2n1>>CCCCNc1nc(N)c2nc(OC)n(CCCN3CCN(CC(C)C)CC3)c2n1 -US20090082399A1,2,O=C(c1ccc(F)cc1)N1CCC[C@H](O)C1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)O[C@H]1CCCN(C(=O)c2ccc(F)cc2)C1 -US20060166990A1,2,Cc1ccc(N)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl.O=C(Cl)OCc1ccccc1>>Cc1ccc(NC(=O)OCc2ccccc2)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl -US20050131014A1,1,CCOc1cc(C=O)ccc1OC.Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>CCOc1cc(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)ccc1OC -US06352985B1,2,COc1ccc(S(N)(=O)=O)cc1.Cc1nc2ccc(C(=O)O)cc2n1Cc1ccccc1Cl>>COc1ccc(S(=O)(=O)NC(=O)c2ccc3nc(C)n(Cc4ccccc4Cl)c3c2)cc1 -US20030166683A1,6,CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(OCC)cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1F>>CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(OCC)cc(OC2CCNCC2)c1F -US20080045493A1,3,C=C[Sn](CCCC)(CCCC)CCCC.O=[N+]([O-])c1ccc(Br)cc1F>>C=Cc1ccc([N+](=O)[O-])c(F)c1 -US20070208033A1,1,CN(CCCCNC(=O)OCc1ccccc1)Cc1ccc(CNCc2ncc[nH]2)cc1.Cn1ccnc1C=O>>CN(CCCCNC(=O)OCc1ccccc1)Cc1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1 -US20070129416A1,2,CCOc1ccccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCCN1CCNCC1>>CCOc1ccccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1 -US05068325,1,COc1ccccc1C=CCCl.Nc1nc2c(s1)CCNCC2>>COc1ccccc1C=CCN1CCc2nc(N)sc2CC1 -US08536165B2,3,Cc1cc([N+](=O)[O-])cnc1Br.OB(O)c1ccccc1>>Cc1cc([N+](=O)[O-])cnc1-c1ccccc1 -US20050239054A1,9,BrC(Br)(Br)Br.OCc1cccc(OCc2ccccc2)c1>>BrCc1cccc(OCc2ccccc2)c1 -US04077982,1,ClCc1cccs1.O[C@H]1CO[C@@H](c2ccccc2)OC1>>c1ccc(C2OCC(OCc3cccs3)CO2)cc1 -US20150119405A1,5,COc1cc(OC)cc(-c2cc(C=O)c([N+](=O)[O-])cc2F)c1.OCCO>>COc1cc(OC)cc(-c2cc(C3OCCO3)c([N+](=O)[O-])cc2F)c1 -US20130029964A1,1,CC(C)(C)[Si](C)(C)Oc1ccc(N)cc1.N#Cc1ccc([N+](=O)[O-])c(Br)c1>>CC(C)(C)[Si](C)(C)Oc1ccc(Nc2cc(C#N)ccc2[N+](=O)[O-])cc1 -US20050239826A1,1,Cc1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCNCC1CC1.OC[C@@H](O)CCl>>Cc1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCN(CC1CC1)C[C@H](O)CO -US05190975,2,CC(=O)Cl.NC1Cc2ccccc2C1>>CC(=O)NC1Cc2ccccc2C1 -US04906633,2,COC(=O)CNCCNC(=O)c1nc(Cl)c(N)nc1N.NCCN>>NCCNC(=O)CNCCNC(=O)c1nc(Cl)c(N)nc1N -US05208247,2,CS(=O)(=O)Cl.NCc1ccccn1>>CS(=O)(=O)NCc1ccccn1 -US20140308282A1,2,NNc1ccccc1.O=C(Cl)C1CCC1>>O=C(NNc1ccccc1)C1CCC1 -US20030130213A1,9,COC(=O)c1nc(F)cnc1N.N>>NC(=O)c1nc(F)cnc1N -US20020015805A1,6,Fc1cc(F)cc(C2CCC3(CC2)OCCO3)c1>>O=C1CCC(c2cc(F)cc(F)c2)CC1 -US20100087427A1,2,Nc1ccccc1.O=C(O)[C@@H]1CN(Cc2ccccc2)C[C@@H]1Cc1ccccc1>>O=C(Nc1ccccc1)[C@@H]1CN(Cc2ccccc2)C[C@@H]1Cc1ccccc1 -US20040235822A1,2,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3CC(C)C)cc1.Nc1ccc(SCc2ccno2)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4ccno4)cc2)CCN3CC(C)C)cc1 -US06235731B1,1,BrCCCc1ccccc1.CC(C)(C)OC(=O)N1CCCNCC1>>CC(C)(C)OC(=O)N1CCCN(CCCc2ccccc2)CC1 -US04410536,1,Cc1csc2ccc3[nH]c4c(c3c12)CNCC4.Fc1ccc(C(CCCI)c2ccc(F)cc2)cc1>>Cc1csc2ccc3[nH]c4c(c3c12)CN(CCCC(c1ccc(F)cc1)c1ccc(F)cc1)CC4 -US20120077781A1,1,Cc1ccc(N)cc1N(C)C.O=C(O)CCCCCBr>>Cc1ccc(NCCCCCC(=O)O)cc1N(C)C -US20090155209A1,6,CC(C)(C)OC(=O)N[C@H]1CCCOCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@@H](OC(=O)N3Cc4cccc(Cl)c4C3)CN2C1=O>>N[C@H]1CCCOCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@@H](OC(=O)N3Cc4cccc(Cl)c4C3)CN2C1=O -US07282501B2,2,CC(C)(C)OC(=O)CCc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1CO.O=C=NC1CCCCC1>>CC(C)(C)OC(=O)CCc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1COC(=O)NC1CCCCC1 -US20070082912A1,6,COC(=O)c1cc(-n2c(C)ccc2-c2cc(F)ccc2OCc2ccc(F)cc2)ccc1OC(F)F>>Cc1ccc(-c2cc(F)ccc2OCc2ccc(F)cc2)n1-c1ccc(OC(F)F)c(C(=O)O)c1 -US20100112090A1,6,CCOC(=O)c1cc(C)c2[nH]c(=O)n(-c3cc(S(=O)(=O)C(C)(C)c4ccccc4)c(OC)cc3Cl)c2n1>>COc1cc(Cl)c(-n2c(=O)[nH]c3c(C)cc(C(=O)O)nc32)cc1S(=O)(=O)C(C)(C)c1ccccc1 -US20080015203A1,6,C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2Cl)cc(C(=O)Nc2cnccn2)c1>>C[C@@H](CO)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2Cl)cc(C(=O)Nc2cnccn2)c1 -US20120225862A1,2,CC(C)(C)c1ccc(S(=O)(=O)NCc2ccc(C(=O)O)cc2)cc1.Nc1cnccc1C(F)(F)F>>CC(C)(C)c1ccc(S(=O)(=O)NCc2ccc(C(=O)Nc3cnccc3C(F)(F)F)cc2)cc1 -US05550240,1,C1CNCCN1.CC(C)(C)Nc1cc(Cl)nc(N2CCCC2)n1>>CC(C)(C)Nc1cc(N2CCNCC2)nc(N2CCCC2)n1 -US20130005707A1,9,CC(C)(C)OC(=O)NCCN1Cc2cc(Br)ccc2C1=O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)OC(=O)NCCN1Cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2C1=O -US20040132716A1,2,CCc1ccc(CC(NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)O)cc1CC.CN1CCN(C2CCNCC2)CC1>>CCc1ccc(CC(NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc1CC -US06008362,1,NNC(N)=S.O=C(CCCCl)c1ccc(O)cc1>>NC(=S)NN=C(CCCCl)c1ccc(O)cc1 -US20140364413A1,2,CS(N)(=O)=O.O=C(O)c1ccc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cn1>>CS(=O)(=O)NC(=O)c1ccc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cn1 -US20110212968A1,5,CCOC(=O)C(F)(F)F.COc1ccc(CCN)cc1OC>>COc1ccc(CCNC(=O)C(F)(F)F)cc1OC -US20120214803A1,7,COc1ccc(C(=O)c2ccc3cccnc3c2[N+](=O)[O-])cc1>>COc1ccc(C(=O)c2ccc3cccnc3c2N)cc1 -US06960688B2,1,C[C@@](O)(C(=O)Nc1ccc(S(=O)(=O)c2ccccc2F)cc1Cl)C(F)(F)F.NCCO>>C[C@@](O)(C(=O)Nc1ccc(S(=O)(=O)c2ccccc2NCCO)cc1Cl)C(F)(F)F -US07026309B2,3,Cc1ccccc1B(O)O.O=C1c2c(I)ccnc2OCCCN1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ccccc1-c1ccnc2c1C(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)CCCO2 -US20070082899A1,2,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.CNc1ccc2c(c1)nc(C(C)(C)OC)n2CC1CCOCC1>>COC(C)(C)c1nc2cc(N(C)S(=O)(=O)c3ccc(NC(C)=O)cc3)ccc2n1CC1CCOCC1 -US04762925,2,Nc1cc(O)ccc1O.O=C(Cl)CCl>>O=C(CCl)Nc1cc(O)ccc1O -US05952341,6,CC(C)(C)OC(=O)N1CCC(Cc2ccc3c(n2)NCCC3)CC1>>c1cc2c(nc1CC1CCNCC1)NCCC2 -US20150259367A1,7,N#CCCCn1c(C(=O)O)cc2cc(Cl)ccc21>>N#CCCCn1c(CO)cc2cc(Cl)ccc21 -US09133168B2,7,Clc1ccccc1-c1cccc2[nH]ccc12>>Clc1ccccc1-c1cccc2c1CCN2 -US20080318956A1,2,CC(C)(C)c1nc(N)sc1C#N.O=C(O)c1cc(Br)ccc1O>>CC(C)(C)c1nc(NC(=O)c2cc(Br)ccc2O)sc1C#N -US20130158002A1,3,CN1c2cc(B3OC(C)(C)C(C)(C)O3)ccc2N(CC2CC2)S1(=O)=O.N#Cc1c(F)cccc1Br>>CN1c2cc(-c3cccc(F)c3C#N)ccc2N(CC2CC2)S1(=O)=O -US20120157439A1,1,COC(=O)c1scc2c(O)ncnc12.COc1ccc(CN)c(OC)c1>>COC(=O)c1scc2c(NCc3ccc(OC)cc3OC)ncnc12 -US20050256099A1,6,COC(=O)c1cc(C)c2c(c1)OCCO2>>Cc1cc(C(=O)O)cc2c1OCCO2 -US05627191,1,BrCc1ccc(-c2ccccc2I)cc1.CCCCc1nc(Cl)c(C=O)[nH]1>>CCCCc1nc(Cl)c(C=O)n1Cc1ccc(-c2ccccc2I)cc1 -US04301166,3,Clc1ccccc1-c1ccccc1.O=C(Cl)CCl>>O=C(CCl)c1ccc(-c2ccccc2Cl)cc1 -US20120022058A1,3,CC1(C)OB(c2ccc3c(c2)CNC3=O)OC1(C)C.Cc1nc(N2N=C(Cl)C[C@@H]2C2CCCC2)ccc1C#N>>Cc1nc(N2N=C(c3ccc4c(c3)CNC4=O)C[C@@H]2C2CCCC2)ccc1C#N -US06825199B2,1,Nc1cc(F)c(F)cc1F.O=C(O)c1cc(F)c(F)cc1F>>O=C(O)c1cc(F)c(F)cc1Nc1cc(F)c(F)cc1F -US20130316938A1,3,CC(C)(C)C1CCCC(CCC=O)C1.c1ccc(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)C1CCCC(CCC=CCc2ccccc2)C1 -US08580815B2,2,COC(=O)c1cc2cc(N)cnc2[nH]1.O=C(Cl)c1ccccc1>>COC(=O)c1cc2cc(NC(=O)c3ccccc3)cnc2[nH]1 -US20050075334A1,6,CN(C)C(=O)Sc1cccc2[nH]c(=O)[nH]c12>>O=c1[nH]c2cccc(S)c2[nH]1 -US20120040960A1,1,O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CNC1.O=C1CCC(O)(c2cccc(O)c2)CC1>>O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(O)(c3cccc(O)c3)CC2)C1 -US05866589,1,CC=O.CCN(c1ncccc1N)C1CCN(Cc2ccccc2)CC1>>CCNc1cccnc1N(CC)C1CCN(Cc2ccccc2)CC1 -US07348324B2,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCN>>CCNC1CCN(C(=O)OC(C)(C)C)CC1 -US05968933,9,O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1>>O=CCCCc1ccc(N(CCCl)CCCl)cc1 -US06034055,2,CC(C)(C)OC(=O)NCC(=O)NCC(=O)O.CCCCCCCC/C=C\CCCCCCCC(=O)N(CCCCCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CN>>CCCCCCCC/C=C\CCCCCCCC(=O)N(CCCCCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CNC(=O)CNC(=O)CNC(=O)OC(C)(C)C -US20020004608A1,1,CCO.CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(O)cc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1F>>CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(OCC)cc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1F -US20070135485A1,2,COC(=O)c1ccc(I)c(N)c1.CS(=O)(=O)Cl>>COC(=O)c1ccc(I)c(NS(C)(=O)=O)c1 -US20070043048A1,2,CC1(C)CC(Nc2nccc(-c3ccc(CCCO)cc3)n2)CC(C)(C)N1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCCc2ccc(-c3ccnc(NC4CC(C)(C)NC(C)(C)C4)n3)cc2)cc1 -US20120302566A1,1,CC(C)(C)c1ccc2c(c1)CC[C@@H]2O.COC(=O)C[C@@H]1COc2cc(O)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4cc(C(C)(C)C)ccc43)ccc21 -US20100093756A1,9,Nc1nc(-c2ccc(C(F)F)o2)nc2sc(C(O)c3ncccc3Cl)cc12>>Nc1nc(-c2ccc(C(F)F)o2)nc2sc(Cc3ncccc3Cl)cc12 -US20080221175A1,7,COC(=O)C[C@@H]1CC[C@@H](N(C(=O)c2ccccc2F)C2CC2)CC1>>O=C(c1ccccc1F)N(C1CC1)[C@@H]1CC[C@@H](CCO)CC1 -US20070167452A1,2,NC[C@H]1CC[C@@H](Cc2ccccc2)CC1.Nc1n[nH]cc1C(=O)O>>Nc1n[nH]cc1C(=O)NC[C@H]1CC[C@@H](Cc2ccccc2)CC1 -US20080242663A1,1,COc1ccc(CO)c(N(C)c2ccnc(Cl)n2)c1.Nc1cc(N2CCOCC2)cc(N2CCOCC2)c1>>COc1ccc(CO)c(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 -US20150126523A1,6,CCOC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1C(F)(F)F>>O=C(O)c1ccc(C2=NOC(c3cc(Cl)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1C(F)(F)F -US20050148624A1,2,CS(=O)(=O)c1ccc(Cn2c(C(=O)O)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1.OCc1ccccn1>>CS(=O)(=O)c1ccc(Cn2c(C(=O)OCc3ccccn3)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1 -US20100179216A1,7,Cc1cc(C#CCOC2CCCCO2)cs1>>Cc1cc(CCCOC2CCCCO2)cs1 -US20130116241A1,1,C1COCCN1.O=c1[nH]ccc2scc(Br)c12>>O=c1[nH]ccc2scc(N3CCOCC3)c12 -US04539154,7,CCOC(=O)C=CC(C)=CCOC(C)=O>>CCOC(=O)C=CC(C)=CCO -US07348324B2,6,COC(=O)c1ccc(CC2CCN(CCCN(C(=O)C3CCN(C(C)=O)CC3)c3ccc(Cl)c(Cl)c3)CC2)cc1>>CC(=O)N1CCC(C(=O)N(CCCN2CCC(Cc3ccc(C(=O)O)cc3)CC2)c2ccc(Cl)c(Cl)c2)CC1 -US20100048648A1,2,C=CCOc1c(C)cc(C(=O)NN)cc1C.CC(C)Cc1ccc(C(=O)O)s1>>C=CCOc1c(C)cc(C(=O)NNC(=O)c2ccc(CC(C)C)s2)cc1C -US20100227887A1,2,CCOC(=O)c1cc(C#N)cc(C)n1.Cc1cccc(N)c1>>Cc1cccc(NC(=O)c2cc(C#N)cc(C)n2)c1 -US05310724,2,CNN.Cc1cc(I)ccc1N=C=S>>Cc1cc(I)ccc1NC(=S)N(C)N -US08071595B2,6,CCOC(=O)Cc1ccc(OC)cc1>>COc1ccc(CC(=O)O)cc1 -US20140066455A1,2,COC(=O)c1cnc(N2CCN3CCCC3C2)nc1.COc1cc(COc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(COc2cc(NC(=O)c3cnc(N4CCN5CCCC5C4)nc3)[nH]n2)cc(OC)c1 -US04835165,1,Clc1ccncc1.NS(=O)(=O)c1ccc(C2CCNCC2)cc1>>NS(=O)(=O)c1ccc(C2CCN(c3ccncc3)CC2)cc1 -US20150038438A1,8,Cn1ccc2cc3c(cc21)C=CCCC3O>>Cn1ccc2cc3c(cc21)C=CCCC3=O -US20090197880A1,3,C#CC(C)(C)C.Fc1cccc(-c2nc3cnn(Cc4cc(-c5ccc(I)cc5)no4)cc-3n2)c1F>>CC(C)(C)C#Cc1ccc(-c2cc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)cc1 -US20140171404A1,6,COc1ccc(Cn2nnnc2CCCC(=O)NC2CCN(C(=O)OCc3cc(Cl)cc(Cl)c3)CC2)cc1>>O=C(CCCc1nnn[nH]1)NC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1 -US20090111867A1,6,CCN1N=C(c2c(C)n(CC(=O)OC(C)(C)C)c3ccc(F)cc23)c2ccccc2S1(=O)=O>>CCN1N=C(c2c(C)n(CC(=O)O)c3ccc(F)cc23)c2ccccc2S1(=O)=O -US20130216498A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(-n3cncn3)nc(-c3cnc4ccc(F)cn34)n2)C1>>Fc1ccc2ncc(-c3nc(N[C@@H]4CCCNC4)cc(-n4cncn4)n3)n2c1 -US20030134859A1,2,CS(=O)(=O)Cl.Nc1ccc(-c2ccc(NC(=O)c3cc([N+](=O)[O-])ccc3Cl)cc2)cc1>>CS(=O)(=O)Nc1ccc(-c2ccc(NC(=O)c3cc([N+](=O)[O-])ccc3Cl)cc2)cc1 -US06867218B2,1,CC/C(CO)=C(\C)c1ccc(Br)cc1.CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC>>CCOC(=O)[C@H](Cc1ccc(OC/C(CC)=C(/C)c2ccc(Br)cc2)cc1)OCC -US20100137610A1,2,CN(c1cc(OC(F)(F)F)cc2cc(C(=O)O)[nH]c12)S(=O)(=O)c1cccs1.COC(OC)C(CN)SCc1ccccc1>>COC(OC)C(CNC(=O)c1cc2cc(OC(F)(F)F)cc(N(C)S(=O)(=O)c3cccs3)c2[nH]1)SCc1ccccc1 -US08063061B2,1,CCI.Cn1nc(-c2ccc3c(c2)c2cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c2n3C)cc1CO>>CCOCc1cc(-c2ccc3c(c2)c2cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c2n3C)nn1C -US20040029887A1,2,NC1CCCCC1.O=C(Cl)CBr>>O=C(CBr)NC1CCCCC1 -US20110306606A1,7,CC(C)c1nc(-c2ccc([N+](=O)[O-])cc2)cs1>>CC(C)c1nc(-c2ccc(N)cc2)cs1 -US08501732B2,6,COC(=O)c1ccc(C(=O)NCc2cn(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1>>O=C(O)c1ccc(C(=O)NCc2cn(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1 -US07807720B2,6,CN(CCCc1ccc(F)cc1)C(=O)OC(C)(C)C>>CNCCCc1ccc(F)cc1 -US20090124596A1,3,Cc1cc(Br)cc(-n2c(=O)n([C@@H]3CC[C@H](NC(=O)c4cn5cc(F)ccc5n4)CC3)c(=O)c3cc(F)cnc32)c1.O=Cc1ccc(B(O)O)cc1>>Cc1cc(-c2ccc(C=O)cc2)cc(-n2c(=O)n([C@@H]3CC[C@H](NC(=O)c4cn5cc(F)ccc5n4)CC3)c(=O)c3cc(F)cnc32)c1 -US07897766B2,2,NC1C2CC3CC1CN(C3)C2.O=C(O)c1ccc2[nH]ccc2c1>>O=C(NC1C2CC3CC1CN(C3)C2)c1ccc2[nH]ccc2c1 -US20040162287A1,1,CN(C)C1(Cc2ccccc2)CCC(=O)CC1.NCc1ccccc1>>CN(C)C1(Cc2ccccc2)CCC(NCc2ccccc2)CC1 -US20100041696A1,2,CC(C)(C)OC(=O)N1CCc2cc(C(=O)O)ccc2C1.Nc1cnn(Cc2cccc3ccccc23)c1>>CC(C)(C)OC(=O)N1CCc2cc(C(=O)Nc3cnn(Cc4cccc5ccccc45)c3)ccc2C1 -US20090143352A1,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)n2cc(-c3cccc4cc[nH]c34)c3cc(Br)cnc32)cc1>>COC(=O)c1cc(-c2cnc3c(c2)c(-c2cccc4cc[nH]c24)cn3S(=O)(=O)c2ccc(C)cc2)ccc1NC(=O)OC(C)(C)C -US07060109B2,1,CCCCOC(=O)c1sc2ccc(O)cc2c1OC(=O)C(C)(C)C.CCOC(=O)CBr>>CCCCOC(=O)c1sc2ccc(OCC(=O)OCC)cc2c1OC(=O)C(C)(C)C -US20080058384A1,2,CC1=C(C(=O)O)C(c2ccc(C(F)(F)F)cc2)CC(=O)N1.Nc1cc2cn[nH]c2cc1F>>CC1=C(C(=O)Nc2cc3cn[nH]c3cc2F)C(c2ccc(C(F)(F)F)cc2)CC(=O)N1 -US20140357675A1,5,COCCl.N#Cc1ccc(O)cn1>>COCOc1ccc(C#N)nc1 -US20120302566A1,1,CC(C)(C)[Si](C)(C)OC1CCc2c1cccc2C(O)C(F)F.CI>>COC(c1cccc2c1CCC2O[Si](C)(C)C(C)(C)C)C(F)F -US20150210640A1,1,CCI.Cc1c(C(=O)O)[nH]c2ccc([N+](=O)[O-])cc12>>CCOC(=O)c1[nH]c2ccc([N+](=O)[O-])cc2c1C -US03991205,2,O=C(Cl)Cl.Oc1cc(Cl)c(Cl)cc1Cl>>O=C(Cl)Oc1cc(Cl)c(Cl)cc1Cl -US20150183801A1,3,Cc1ccc(F)cc1B(O)O.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2C[C@H](O)[C@@H](O)C2)c(Br)c1>>Cc1ccc(F)cc1-c1cc(C(=O)Nc2ccc(OC(F)(F)Cl)cc2)cnc1N1C[C@H](O)[C@@H](O)C1 -US04326055,1,C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C.ClCc1ccccc1>>C/C(=C\c1ccc(C(=O)OCc2ccccc2)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C -US20110269806A1,3,CC(C)(C)NS(=O)(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1.COc1c(Br)cc(S(=O)(=O)NC(C)=O)cc1C=O>>COc1c(C=O)cc(S(=O)(=O)NC(C)=O)cc1-c1cccc(S(=O)(=O)NC(C)(C)C)c1 -US08344135B2,2,Cc1ccc(Oc2ccc3nc(N)sc3n2)cc1NC(=O)c1cccc(C2(C#N)CC2)c1.O=C(Cl)c1cocn1>>Cc1ccc(Oc2ccc3nc(NC(=O)c4cocn4)sc3n2)cc1NC(=O)c1cccc(C2(C#N)CC2)c1 -US08067638B2,2,Nc1ccc2ncsc2c1.O=C(Cl)c1cccc(NC(=O)c2ccccc2)c1>>O=C(Nc1cccc(C(=O)Nc2ccc3ncsc3c2)c1)c1ccccc1 -US07217723B2,7,CN(CC(=O)c1ccc(F)cc1)Cc1ccccc1>>CN(Cc1ccccc1)CC(O)c1ccc(F)cc1 -US20150057271A1,3,C=CB1OC(C)(C)C(C)(C)O1.COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCCN3c2ccc(C(F)(F)F)cc2Br)cc1>>C=Cc1cc(C(F)(F)F)ccc1N1CCOc2cc(S(=O)(=O)N(Cc3ccc(OC)cc3)c3nccs3)ccc21 -US08362073B2,8,COc1ccc(C(=O)NC2(C(=O)O)Cc3ccccc3C2)cc1OCCc1cccc(SC)c1.OO>>COc1ccc(C(=O)NC2(C(=O)O)Cc3ccccc3C2)cc1OCCc1cccc(S(C)=O)c1 -US05130329,6,CN(Cc1ccccc1)[C@@H]1CCCc2ccccc2[C@H]1N1CCCC1>>CN[C@@H]1CCCc2ccccc2[C@H]1N1CCCC1 -US20040082570A1,9,Cn1c(=O)c2c(nc(N3CCN(C(=O)OC(C)(C)C)CC3)n2-c2ccccc2C=O)n(C)c1=O.NO>>Cn1c(=O)c2c(nc(N3CCN(C(=O)OC(C)(C)C)CC3)n2-c2ccccc2C=NO)n(C)c1=O -US08598154B2,2,O=C(Cl)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2.OC1CCC1>>O=C(OC1CCC1)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2 -US20030069419A1,1,COc1ccc(CCCCCl)cc1.c1c[nH]nn1>>COc1ccc(CCCCn2ccnn2)cc1 -US20080161289A1,1,Brc1ccc(-c2nc3c(s2)CCN(C2CCC2)CC3)cc1.CN1CCNC1=O>>CN1CCN(c2ccc(-c3nc4c(s3)CCN(C3CCC3)CC4)cc2)C1=O -US08269008B2,2,CCOC(=O)c1ncc2c(C3=CCCCC3)noc2c1O.NCC(=O)O>>O=C(O)CNC(=O)c1ncc2c(C3=CCCCC3)noc2c1O -US08440417B2,7,CC(C)(C)OC(=O)NCCNS(=O)(=O)c1cccc(C#N)c1>>CC(C)(C)OC(=O)NCCNS(=O)(=O)c1cccc(CN)c1 -US20070232607A1,2,CNCCO.Cc1ccc(Oc2ccc(Nc3ncnc4cccc(OCC(=O)O)c34)cc2C)cn1>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(OCC(=O)N(C)CCO)c34)cc2C)cn1 -US04337256,2,Cc1ccccc1CCN.O=C(O)c1ccc(Br)cc1>>Cc1ccccc1CCNC(=O)c1ccc(Br)cc1 -US05578242,7,CCCCC(=O)c1ccc(Br)cc1>>CCCCCc1ccc(Br)cc1 -US04935437,1,Cc1c[nH]cn1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US04778912,6,CCCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCCCCCCCCCC[N+](C)(C)C)OCc1ccccc1>>CCCCCCCCCCCCCCCCCCOCC(O)COP(=O)([O-])OCCCCCCCCCC[N+](C)(C)C -US20070149546A1,1,C[C@@H](O)CN.Cc1cc(Nc2ncnc3cccc(F)c23)ccc1O>>Cc1cc(Nc2ncnc3cccc(O[C@H](C)CN)c23)ccc1O -US20120329775A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CN1C(=O)COc2ccc(Br)cc21>>CN1C(=O)COc2ccc(B3OC(C)(C)C(C)(C)O3)cc21 -US20140107096A1,2,COC(=O)c1cc(Br)ccc1N.O=C(Cl)COc1ccccc1>>COC(=O)c1cc(Br)ccc1NC(=O)COc1ccccc1 -US20100273767A1,1,CCBr.O=C1CC2CNCCN2c2ccccc2N1>>CCN1CCN2c3ccccc3NC(=O)CC2C1 -US20070281946A1,2,CS(=O)(=O)c1ccc(/C(=C\c2cccs2)C(=O)O)cc1.Nc1ncc(Cl)s1>>CS(=O)(=O)c1ccc(/C(=C\c2cccs2)C(=O)Nc2ncc(Cl)s2)cc1 -US20150239844A1,3,COc1ccc(C(O)(c2ccc(Cl)cc2)c2ccc3nc(OC(C)(C)C)cc(Br)c3c2)cc1.OB(O)/C=C/c1ccccc1>>COc1ccc(C(O)(c2ccc(Cl)cc2)c2ccc3nc(OC(C)(C)C)cc(/C=C/c4ccccc4)c3c2)cc1 -US20100041892A1,6,COCOc1cc(C(=O)OC)n(Cc2ccc(C(F)(F)F)cc2Cl)n1>>COCOc1cc(C(=O)O)n(Cc2ccc(C(F)(F)F)cc2Cl)n1 -US07989620B2,3,C#CC1=CCN(S(=O)(=O)C[C@@]2(C)NC(=O)NC2=O)CC1.COc1ncc(Br)cn1>>COc1ncc(C#CC2=CCN(S(=O)(=O)C[C@@]3(C)NC(=O)NC3=O)CC2)cn1 -US06479424B1,7,Cc1cc2c(cc1C)C(=O)CC2>>Cc1cc2c(cc1C)C(O)CC2 -US04962203,9,CC(Oc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1)C(=O)O.N>>CC(Oc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1)C(N)=O -US20150141427A1,2,Nc1ccc(CC(F)(F)F)cc1.O=C(O)c1cccc(-c2cncnc2)c1>>O=C(Nc1ccc(CC(F)(F)F)cc1)c1cccc(-c2cncnc2)c1 -US04044010,1,Cc1ccc2c(c1)CC(Cl)c1cc(F)ccc1S2.O=C1OCCN1CCN1CCNCC1>>Cc1ccc2c(c1)CC(N1CCN(CCN3CCOC3=O)CC1)c1cc(F)ccc1S2 -US20110046134A1,2,CC(C)(C)OC(=O)NCC(=O)O.c1ccc(CN2CCNCC2)cc1>>CC(C)(C)OC(=O)NCC(=O)N1CCN(Cc2ccccc2)CC1 -US08088925B2,2,CNC1CCN(C(C)C)CC1.O=C1c2ccccc2C(=O)N1CCS(=O)(=O)Cl>>CC(C)N1CCC(N(C)S(=O)(=O)CCN2C(=O)c3ccccc3C2=O)CC1 -US20150166589A1,2,COc1cc(N)ccn1.O=C(Cl)c1ccc(C(F)(F)F)cc1F>>COc1cc(NC(=O)c2ccc(C(F)(F)F)cc2F)ccn1 -US20150080341A1,7,CC(=O)N[C@@]1(C(=O)NC(C)(C)C)C[C@@H](C[N+](=O)[O-])C[C@@H]1CCCB1OC(C)(C)C(C)(C)O1>>CC(=O)N[C@@]1(C(=O)NC(C)(C)C)C[C@@H](CN)C[C@@H]1CCCB1OC(C)(C)C(C)(C)O1 -US20070275968A1,1,CC1(C)OB(c2ccc(CBr)cc2)OC1(C)C.C[S-]>>CSCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1 -US06608062B1,3,CCn1ncnc1COc1nc2c(-c3ccccc3)nnc(C)n2c1Br.OB(O)c1cccs1>>CCn1ncnc1COc1nc2c(-c3ccccc3)nnc(C)n2c1-c1cccs1 -US20080300290A1,6,CCOC(=O)C(C)(C)Oc1ccc(-c2cn(CCC(C)(C)NC(=O)OC(C)(C)C)cn2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(-c2cn(CCC(C)(C)N)cn2)cc1 -US20150141406A1,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cs1.COc1ccc(Cn2nc(OS(=O)(=O)C(F)(F)F)c3c(OC)nccc32)cc1>>COC(=O)c1cc(-c2nn(Cc3ccc(OC)cc3)c3ccnc(OC)c23)cs1 -US20120101097A9,2,Nc1ccc(Cl)cc1-c1nccc2ccccc12.O=S(=O)(Cl)c1ccc(-c2cnco2)cc1>>O=S(=O)(Nc1ccc(Cl)cc1-c1nccc2ccccc12)c1ccc(-c2cnco2)cc1 -US20080312243A1,6,CC#CCn1c(C(=O)OCC)cnc1N1CCCC(NC(=O)OC(C)(C)C)C1>>CC#CCn1c(C(=O)O)cnc1N1CCCC(NC(=O)OC(C)(C)C)C1 -US20140315928A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.Cc1ccc[n+]([O-])c1Cl>>Cc1ccc[n+]([O-])c1N[C@@H]1CCCN(C(=O)OC(C)(C)C)C1 -US07166639B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1sc(-c2ccc(Cl)cc2)cc1N>>COC(=O)c1sc(-c2ccc(Cl)cc2)cc1NC(=O)OC(C)(C)C -US20120094958A1,3,CC(C)(C)OC(=O)n1cccc1B(O)O.CCOC(=O)c1ccc2cc(I)cc(-c3cccc4ccccc34)c2n1>>CCOC(=O)c1ccc2cc(-c3cccn3C(=O)OC(C)(C)C)cc(-c3cccc4ccccc34)c2n1 -US20070225290A1,1,CCCC(CC(O)(C=O)C(F)(F)F)c1cccc(F)c1OC.Cc1ncc2c(N)cc(F)cc2n1>>CCCC(CC(O)(C=Nc1cc(F)cc2nc(C)ncc12)C(F)(F)F)c1cccc(F)c1OC -US20110092461A1,2,CNc1ccc(C(=O)OC)cc1.CS(=O)(=O)Cl>>COC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 -US20130237525A1,1,FCCI.O=C1C(O)CC(c2c(O)cccc2F)N1Cc1ccc(OC(F)(F)F)cc1>>O=C1C(O)CC(c2c(F)cccc2OCCF)N1Cc1ccc(OC(F)(F)F)cc1 -US20120010189A1,1,CS(=O)(=O)OC1CN(C(=O)c2nnc(-c3ccccc3)o2)C1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OC2CN(C(=O)c3nnc(-c4ccccc4)o3)C2)cc1 -US20110124665A1,1,COc1ccc(-c2c(-c3ccccc3)oc3ncnc(OCC4CCCN4)c23)cc1.N#CCCCBr>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(OCC4CCCN4CCCC#N)c23)cc1 -US05466698,3,Brc1ccc2[nH]ccc2c1.C#CCCN1CC=C(c2ccccc2)CC1>>C(#Cc1ccc2[nH]ccc2c1)CCN1CC=C(c2ccccc2)CC1 -US05977141,1,CC(C)CN.CCOC(=O)CBr>>CCOC(=O)CNCC(C)C -US07897616B2,2,CCCCCCN=C=O.Cn1c(=O)[nH]c2ncccc21>>CCCCCCNC(=O)n1c(=O)n(C)c2cccnc21 -US06514971B1,1,Cc1cc(F)c(N)cc1O.Clc1ccc2nncc(Cl)c2c1>>Cc1cc(F)c(Nc2cnnc3ccc(Cl)cc23)cc1O -US20070219214A1,1,CN(C[C@@H](CC=O)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1.CNC(=O)C1(N2CCCCC2)CCNCC1>>CNC(=O)C1(N2CCCCC2)CCN(CC[C@H](CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 -US06143769,2,CC(=O)Cl.CCOc1cc(CC(=O)NC(CO)c2ccccc2N2CCCCC2)ccc1C(=O)OCc1ccccc1>>CCOc1cc(CC(=O)NC(COC(C)=O)c2ccccc2N2CCCCC2)ccc1C(=O)OCc1ccccc1 -US20070254931A1,4,CCOC(=O)C(=O)C(Br)Cc1cccc(SC)c1.NC(N)=S>>CCOC(=O)c1nc(N)sc1Cc1cccc(SC)c1 -US06867224B2,9,N#CCC1COc2ccc(S(=O)(=O)Cl)cc2C1>>N#CCC1COc2ccc(S)cc2C1 -US06300353B1,6,C[C@@H](OC1CCCCO1)C(O)(Cn1cncn1)c1cc(F)c(F)cc1F>>C[C@@H](O)[C@](O)(Cn1cncn1)c1cc(F)c(F)cc1F -US20100041892A1,3,CC(C)Oc1cc(C=O)n(Cc2ncc(C(F)(F)F)cc2Cl)n1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ncc(C(F)(F)F)cc1Cl -US20070191364A1,1,CC1CN(C(=O)OC(C)(C)C)CCC1=O.NC1CCCCC1>>C[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NC1CCCCC1 -US20070191364A1,1,CC1CN(C(=O)OC(C)(C)C)CCC1=O.NC1CCCCC1>>C[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1NC1CCCCC1 -US20080070884A1,6,COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)OCc1ccccc1>>CC(C)C[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)O -US20140038937A1,2,C1COCCN1.O=C(O)c1ccc2occc(=O)c2c1>>O=C(c1ccc2occc(=O)c2c1)N1CCOCC1 -US20150218096A1,6,CCOC(=O)c1cc(F)c(-c2nn(C(=O)c3c(Cl)cccc3C3CCC3)c3cccnc23)c(F)c1>>O=C(O)c1cc(F)c(-c2nn(C(=O)c3c(Cl)cccc3C3CCC3)c3cccnc23)c(F)c1 -US20040127502A1,2,COc1cccc(Nc2cc(N(C)C)nc(N3CCNCC3)n2)c1.O=C(Cl)c1cccs1>>COc1cccc(Nc2cc(N(C)C)nc(N3CCN(C(=O)c4cccs4)CC3)n2)c1 -US05223510,3,CCCCC(=O)Cl.O=[N+]([O-])c1ccc(O)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1>>O=P(c1ccccc1)(c1ccccc1)c1ccccc1 -US06110937,1,CC(C)(C)OC(=O)N1CCC[C@H](CO)C1.Cc1cc(Br)cc(C)c1O>>Cc1cc(Br)cc(C)c1OC[C@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20090029903A1,6,CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(OCC(=O)OC)cc3)S(=O)(=O)c3cccs3)cc2)cc1>>CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(OCC(=O)O)cc3)S(=O)(=O)c3cccs3)cc2)cc1 -US04125732,1,ClCCCBr.O=C(O)Cc1ccc(O)cc1>>O=C(O)Cc1ccc(OCCCCl)cc1 -US08946260B2,1,CCn1ccc2c1C(=O)NCC2.Cc1ccncc1I>>CCn1ccc2c1C(=O)N(c1cnccc1C)CC2 -US20050119489A1,6,CCc1nn(C[C@H](C)NC(=O)OC(C)(C)C)c(CC)c1S(=O)(=O)c1cccc(N2C(=O)CC(C)(C)CC2=O)c1>>CCc1nn(C[C@H](C)N)c(CC)c1S(=O)(=O)c1cccc(N2C(=O)CC(C)(C)CC2=O)c1 -US08680108B2,1,CC(=O)c1cc(Cl)c2cccnc2c1N1CCN(C(=O)C2CCN(C(C)=O)CC2)CC1.[NH4+]>>CC(=O)N1CCC(C(=O)N2CCN(c3c(C(C)N)cc(Cl)c4cccnc34)CC2)CC1 -US20090311217A1,3,COc1ccc2[nH]c(Br)c(C=O)c2c1.Cc1noc(C)c1B(O)O>>COc1ccc2[nH]c(-c3c(C)noc3C)c(C=O)c2c1 -US20090076086A1,2,NCCC1CCCCC1.O=C(O)c1cccnc1SCCS(=O)(=O)c1ccccc1>>O=C(NCCC1CCCCC1)c1cccnc1SCCS(=O)(=O)c1ccccc1 -US20070225340A1,3,COc1ccc(Br)cc1B(O)O.Ic1ccccc1I>>COc1ccc(Br)cc1-c1ccccc1I -US20090048251A1,2,CNCCO.COC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cscn4)c3)c12>>C[C@@H](Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cscn4)c3)c12)C(=O)N(C)CCO -US20140350011A1,4,COc1cc(CN2CCOCC2)ccc1N=C=S.NC(=O)[C@@H]1[C@H](Nc2c(Cl)cnc(N)c2N)[C@H]2C=C[C@@H]1C2>>COc1cc(CN2CCOCC2)ccc1Nc1nc2c(N[C@@H]3[C@H]4C=C[C@H](C4)[C@@H]3C(N)=O)c(Cl)cnc2[nH]1 -US20100222349A1,3,CC(C)(C)OC(=O)N1CCC(Oc2cc(Cl)cc3cccnc23)CC1.CCCCCC[Mg+]>>CCCCCCc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c2ncccc2c1 -US20060041123A1,6,COC(=O)C1(C)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1 -US20070117798A1,7,CC(=O)CN[C@@H](C)c1ccc(F)cc1>>CC(O)CN[C@@H](C)c1ccc(F)cc1 -US05371086,2,CC(=O)Cl.Nc1ccc([N+](=O)[O-])cn1>>CC(=O)Nc1ccc([N+](=O)[O-])cn1 -US20100120778A1,3,CC(=O)C(=O)c1ccc(Cl)cc1.CS(=O)(=O)c1cccc(B(O)O)c1>>CC(=O)C(=O)c1ccc(-c2cccc(S(C)(=O)=O)c2)cc1 -US05556861,6,CC1(NC2CC2)CN(C(c2ccccc2)c2ccccc2)C1>>CC1(NC2CC2)CNC1 -US20040138223A1,2,CC(C)c1ccc(NCc2ccc(N(C)C)cc2)cn1.COc1ccc2c(c1)C(C(=O)O)CCC2>>COc1ccc2c(c1)C(C(=O)N(Cc1ccc(N(C)C)cc1)c1ccc(C(C)C)nc1)CCC2 -US04876349,3,CC(c1ccc2c(c1)C(C)(C)CCC2(C)C)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccncc1>>C/C(=C\c1ccncc1)c1ccc2c(c1)C(C)(C)CCC2(C)C -US20150191434A1,6,CCOC(=O)c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cccc(F)c12>>O=C(O)c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cccc(F)c12 -US08450319B2,1,CC(C)I.COc1ccc(Br)cc1O>>COc1ccc(Br)cc1OC(C)C -US20130123235A1,6,CC(=O)OC1CN(C(=O)OC(C)(C)C)C1>>CC(=O)OC1CNC1 -US20100266504A1,3,Clc1ccc2c(n1)CCN(Cc1ccccc1)C2.OB(O)C1CC1>>c1ccc(CN2CCc3nc(C4CC4)ccc3C2)cc1 -US05374656,2,CC(C)(C)OC(=O)C(Nc1ccccc1)c1ccccc1Cl.Cc1cccc(NC(=O)NCC(=O)O)c1>>Cc1cccc(NC(=O)NCC(=O)N(c2ccccc2)C(C(=O)OC(C)(C)C)c2ccccc2Cl)c1 -US20110059965A1,6,O=C(N1CCc2ccc(S(=O)(=O)Nc3nccs3)cc2C1)C(F)(F)F>>O=S(=O)(Nc1nccs1)c1ccc2c(c1)CNCC2 -US20080242663A1,1,C1COCCN1.CCOC(=O)c1cc(F)cc([N+](=O)[O-])c1>>CCOC(=O)c1cc(N2CCOCC2)cc([N+](=O)[O-])c1 -US07232827B2,7,CCOC(=O)C1Cc2nccnc2C1>>OCC1Cc2nccnc2C1 -US20100272680A1,2,O=C(O)c1nc2c(C(F)(F)F)cc(-c3cn[nH]c3)cn2c1Cl.O=C1CN(C2CCNCC2)C(=O)N1>>O=C1CN(C2CCN(C(=O)c3nc4c(C(F)(F)F)cc(-c5cn[nH]c5)cn4c3Cl)CC2)C(=O)N1 -US20040127706A1,2,COC(=O)[C@@H](N)Cc1ccc(-c2c(C(F)(F)F)cc(C)n(C)c2=O)cc1.O=C(Cl)c1c(Cl)cccc1Cl>>COC(=O)[C@H](Cc1ccc(-c2c(C(F)(F)F)cc(C)n(C)c2=O)cc1)NC(=O)c1c(Cl)cccc1Cl -US06924300B2,6,COC(=O)CCCCCC/C(=N/OCc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)c1ccc(Cl)cc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(/CCCCCCC(=O)O)c2ccc(Cl)cc2)cc1 -US05204018,3,CCCCC[C@@H]1CC[C@@H](C=O)CC1.c1ccc([P+](CCCc2ccc(OC3CCCCO3)cc2)(c2ccccc2)c2ccccc2)cc1>>CCCCC[C@@H]1CC[C@@H](C=CCCc2ccc(OC3CCCCO3)cc2)CC1 -US04187216,2,C[C@H](N)C(=O)N[C@@H](C)C(=O)Nc1ccccc1.O=C(Cl)c1ccccc1>>C[C@H](NC(=O)c1ccccc1)C(=O)N[C@@H](C)C(=O)Nc1ccccc1 -US20120207679A1,3,CC1(C)OB(c2ccc(N3CCOCC3)nc2)OC1(C)C.Oc1ccc2nc(Br)sc2c1>>Oc1ccc2nc(-c3ccc(N4CCOCC4)nc3)sc2c1 -US06875884B1,1,CCI.O=C1c2ccccc2C(=O)N1CCCNCCc1ccc(Cl)cc1>>CCN(CCCN1C(=O)c2ccccc2C1=O)CCc1ccc(Cl)cc1 -US20150018341A1,6,COc1ccc(C(=O)c2ccc(OCCBr)c(F)c2)cc1>>O=C(c1ccc(O)cc1)c1ccc(OCCBr)c(F)c1 -US20140057926A1,8,Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(=NC#N)C3CC3)cc2)cn1C(C)C.O=C(OO)c1cccc(Cl)c1>>Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(=O)(=NC#N)C3CC3)cc2)cn1C(C)C -US07786129B2,1,CCC1(CCCCCl)C(=O)Nc2ccc(F)cc21.Fc1ccc(N2CCNCC2)cc1>>CCC1(CCCCN2CCN(c3ccc(F)cc3)CC2)C(=O)Nc2ccc(F)cc21 -US20140005164A1,4,COC(=O)[C@@H]1CC[C@@H](CNc2cc(OC3CCCCO3)ccc2N)CC1.O=C(n1ccnc1)n1ccnc1>>COC(=O)[C@@H]1CC[C@@H](Cn2c(=O)[nH]c3ccc(OC4CCCCO4)cc32)CC1 -US20100331293A1,3,Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl.Cc1ccncc1B(O)O>>Cc1ccncc1-c1nc2cc(F)cc(F)c2c(Cl)c1C -US20080280872A1,1,COC(=O)c1cc(O)cc(OS(=O)(=O)c2ccc(C)cc2)c1.OB(O)c1cc(F)cc(F)c1>>COC(=O)c1cc(Oc2cc(F)cc(F)c2)cc(OS(=O)(=O)c2ccc(C)cc2)c1 -US06831174B2,2,CC(C)(C)C(=O)Cl.O=C(OC[C@@H]1O[C@@H](O)CS1)c1ccccc1>>CC(C)(C)C(=O)O[C@H]1CS[C@H](COC(=O)c2ccccc2)O1 -US20100137313A1,1,COC(=O)c1cc(Br)cnc1Cl.NCCN1CCOCC1>>COC(=O)c1cc(Br)cnc1NCCN1CCOCC1 -US07910613B2,2,CC(C)CC(=O)Cl.Cc1nc(-c2sc(N)nc2-c2ccccc2)no1>>Cc1nc(-c2sc(NC(=O)CC(C)C)nc2-c2ccccc2)no1 -US20130225646A1,7,NCC(=O)c1cccc(Cl)c1Cl>>NCC(O)c1cccc(Cl)c1Cl -US20110124661A1,1,OCc1ccccc1.Oc1ccc(Br)nc1>>Brc1ccc(OCc2ccccc2)cn1 -US20150051395A1,1,COC(=O)c1ncc(Br)cc1F.NS(=O)(=O)c1ccncc1>>COC(=O)c1ncc(NS(=O)(=O)c2ccncc2)cc1F -US05051437,1,Cc1cc(CCCCCBr)on1.N#Cc1cc(Cl)c(O)c(Cl)c1>>Cc1cc(CCCCCOc2c(Cl)cc(C#N)cc2Cl)on1 -US20130267554A1,10,Br.CCOC(=O)C(C)(C)CCC=Cc1ccccc1Cl>>CCOC(=O)C(C)(C)CCCC(Br)c1ccccc1Cl -US07230007B2,1,Clc1ccc2ccccc2n1.c1cnc2[nH]ccc2c1>>c1ccc2nc(-n3ccc4cccnc43)ccc2c1 -US20150126485A1,1,CN(C)[C@H]1CNC[C@@H]1O.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2ccn[nH]2)c1>>CN(C)[C@H]1CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc2-c2ccn[nH]2)C[C@@H]1O -US05283241,2,CC(C)(CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3N)cc2)C1=O)NC(=O)OC(C)(C)C.CC(C)N=C=O>>CC(C)NC(=O)Nc1ccccc1-c1ccc(CN2C(=O)[C@H](NC(=O)CC(C)(C)NC(=O)OC(C)(C)C)CCc3ccccc32)cc1 -US06686352B2,6,CCOC(=O)c1cccc2c1N1CN=C(C)C1=Cc1cncnc1-2>>CC1=NCN2C1=Cc1cncnc1-c1cccc(C(=O)O)c12 -US20040039061A1,6,COC(=O)c1ccc(Cc2c(C)c(OC)c(OC)c(OC)c2OC)cc1-c1cccnc1>>COc1c(C)c(Cc2ccc(C(=O)O)c(-c3cccnc3)c2)c(OC)c(OC)c1OC -US06235764B1,3,CN(C)C=O.Fc1cc(F)cc(Cl)c1>>O=Cc1c(F)cc(Cl)cc1F -US06492522B1,1,COC(=O)C(CC1CCNCC1)C(=O)OC.ClCc1ccccc1>>COC(=O)C(CC1CCN(Cc2ccccc2)CC1)C(=O)OC -US08445490B2,2,CC(C)(C)OC(=O)NCCCCN.O=C(O)c1ccc(Nc2nc(NCc3ccc(OCCBr)cc3)nc(OCC(F)(F)F)n2)cc1>>CC(C)(C)OC(=O)NCCCCNC(=O)c1ccc(Nc2nc(NCc3ccc(OCCBr)cc3)nc(OCC(F)(F)F)n2)cc1 -US20100311798A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)CCc1ccc(Cl)cc1>>COC(=O)[C@H](CCc1ccc(Cl)cc1)NC(=O)OC(C)(C)C -US06962923B2,1,COc1ccc(-c2c(OCCO)nn(C)c2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1.Clc1ncc(Br)cn1>>COc1ccc(-c2c(OCCOc3ncc(Br)cn3)nn(C)c2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1 -US20100144747A1,3,CCCC[Sn](CCCC)(CCCC)c1cnccn1.COC(=O)c1cc(I)c(C(F)(F)F)cc1N>>COC(=O)c1cc(-c2cnccn2)c(C(F)(F)F)cc1N -US04888323,8,CC(C)(C)C1CCC(O)C(C(C)(C)C)C1>>CC(C)(C)C1CCC(=O)C(C(C)(C)C)C1 -US08426447B2,7,CC(C)(C)C#Cc1cnc2c(c1)[C@]1(COC(N)=N1)c1cc(-c3cccnc3)ccc1O2>>CC(C)(C)CCc1cnc2c(c1)[C@]1(COC(N)=N1)c1cc(-c3cccnc3)ccc1O2 -US20080051420A1,2,O=S(=O)(Cl)C1CC1.Oc1ccc(C2(c3cccc(Br)c3)NC(=S)N3CCCN=C32)cc1>>O=S(=O)(Oc1ccc(C2(c3cccc(Br)c3)NC(=S)N3CCCN=C32)cc1)C1CC1 -US04680291,7,CN(C#CCC1=CCCCC1)Cc1cccc2ccccc12>>CN(/C=C\CC1=CCCCC1)Cc1cccc2ccccc12 -US06071927,1,CI.Oc1ccc(OCC(F)(F)F)cc1Br>>COc1ccc(OCC(F)(F)F)cc1Br -US20140323468A1,6,CC(C)(C)OC(=O)N1CCCc2cc(-c3cncc(Br)c3)cnc21>>Brc1cncc(-c2cnc3c(c2)CCCN3)c1 -US05277895,1,BrCc1ccccc1.OCCCCCCCCCO>>OCCCCCCCCCOCc1ccccc1 -US07842685B2,1,COC(=O)CBr.c1ccc(C2(c3ccc4nc(-c5ccc6c(c5)CNC6)sc4n3)CC2)cc1>>COC(=O)CN1Cc2ccc(-c3nc4ccc(C5(c6ccccc6)CC5)nc4s3)cc2C1 -US20070293567A1,1,COC(=O)C(CC(C)C)c1cc(OS(=O)(=O)C(F)(F)F)cc(-c2cc(F)cc(C(F)(F)F)c2)c1.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COC(=O)C(CC(C)C)c1cc(Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(-c2cc(F)cc(C(F)(F)F)c2)c1 -US06441049B2,8,COc1ccc(OC)c2c1C[C@@H](C)[C@H](O)C2>>COc1ccc(OC)c2c1CC(=O)C(C)C2 -US20140073651A1,1,COC(=O)c1cc(I)ccc1Cl.Oc1cccnc1>>COC(=O)c1cc(Oc2cccnc2)ccc1Cl -US05919936,2,Nc1ccc2[nH]cc(C3CCN(CCc4ccccc4)CC3)c2n1.O=C(Cl)c1ccsc1>>O=C(Nc1ccc2[nH]cc(C3CCN(CCc4ccccc4)CC3)c2n1)c1ccsc1 -US20090280106A1,1,COC(=O)c1cnc(Br)s1.NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)c1cnc(NCCSC(c2ccccc2)(c2ccccc2)c2ccccc2)s1 -US08658641B2,9,C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc(C(=O)C(F)(F)F)c(F)c2F)C[C@@H](C)O1.NO>>C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc(C(=NO)C(F)(F)F)c(F)c2F)C[C@@H](C)O1 -US20040097503A1,1,COc1cccc(N)c1OC.Cc1cc(Cl)nc(-c2ccccn2)n1>>COc1cccc(Nc2cc(C)nc(-c3ccccn3)n2)c1OC -US07691869B2,1,CS(=O)(=O)OCCn1ccc2c1nc(N)n1nc(-c3ccco3)nc21.Fc1ccc(CN2CCNCC2)c(F)c1>>Nc1nc2c(ccn2CCN2CCN(Cc3ccc(F)cc3F)CC2)c2nc(-c3ccco3)nn12 -US08729268B2,7,CP(C)(=O)c1cccc([N+](=O)[O-])c1>>CP(C)(=O)c1cccc(N)c1 -US20120071514A1,3,CC(O)c1ccncc1Br.Cn1c(=O)oc2ccc(B3OC(C)(C)C(C)(C)O3)cc21>>CC(O)c1ccncc1-c1ccc2oc(=O)n(C)c2c1 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.Cc1cccc(B(O)O)c1>>CCCNC(=O)c1nnc2c(-c3cccc(C)c3)cccc2c1N -US20130165660A1,1,CC(C)c1cccc(C(C)C)c1N.Cc1ccccc1Br>>Cc1ccccc1Nc1c(C(C)C)cccc1C(C)C -US20120289520A1,1,CI.Oc1cc(Cl)c(Br)cc1Cl>>COc1cc(Cl)c(Br)cc1Cl -US06566547B1,2,CO.O=C(O)Cc1ccccc1Oc1ccccc1>>COC(=O)Cc1ccccc1Oc1ccccc1 -US05478835,2,CCc1cccc(CC)c1N.Cc1ccc2c(c1)C(C(=O)O)c1ccccc1CO2>>CCc1cccc(CC)c1NC(=O)C1c2ccccc2COc2ccc(C)cc21 -US06693123B2,3,C#CC(C)(C)C.COC(=O)c1ccc([N+](=O)[O-])cc1Br>>COC(=O)c1ccc([N+](=O)[O-])cc1C#CC(C)(C)C -US20140011777A1,6,CCOCc1nc2c(N)nc3ccccc3c2n1CC1(O)CCN(C(=O)OC(C)(C)C)CC1>>CCOCc1nc2c(N)nc3ccccc3c2n1CC1(O)CCNCC1 -US07511037B2,2,CC1(C)OCCn2c1nc(C(=O)O)c(OCc1ccccc1)c2=O.CNC(=O)c1cc(F)ccc1CN>>CNC(=O)c1cc(F)ccc1CNC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CCOC2(C)C -US20090062268A1,1,C=O.NC(=O)c1cccc2[nH]c(C3CCC4(CC4)N3)nc12>>CN1C(c2nc3c(C(N)=O)cccc3[nH]2)CCC12CC2 -US20130178631A1,3,Brc1ccccn1.C#CCCn1cc(-c2ccc(F)cc2)nn1>>Fc1ccc(-c2cn(CCC#Cc3ccccn3)nn2)cc1 -US06140322,7,CC1Cc2ccc([N+](=O)[O-])cc2CN1>>CC1Cc2ccc(N)cc2CN1 -US07777042B2,6,CC(C)Oc1ccc(C[C@H](NC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cccc(F)c2)C(=O)OCc2ccccc2)cc1>>CC(C)Oc1ccc(C[C@H](NC(=O)C2CCCCN2S(=O)(=O)c2cccc(F)c2)C(=O)O)cc1 -US06727264B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3cccc(Cl)c3)CC2)c1.COc1ccc(NN)cc1>>COc1ccc2[nH]c(-c3cccc(Cl)c3)c(CCCN3CCC(c4cccc(NC(=O)C(C)C)c4)CC3)c2c1 -US05962473,2,CN1CCC(c2c[nH]c3ccc(N)cc23)CC1.O=C(O)c1ccccn1>>CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccccn4)cc23)CC1 -US20030229079A1,7,O=[N+]([O-])c1cc(Cc2ccccc2)cc(Br)c1O>>Nc1cc(Cc2ccccc2)cc(Br)c1O -US08129424B2,6,COCCc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1>>COCCc1cc2ccccc2n1-c1ccc(O)cc1 -US08889671B2,1,C1=COCCC1.COC(=O)[C@@H](NC(=O)OCc1ccccc1)[C@@H](C)O>>COC(=O)[C@@H](NC(=O)OCc1ccccc1)[C@@H](C)OC1CCCCO1 -US08629166B2,7,O=C(Nc1cccnc1)c1cnc(OCC(F)(F)F)c(C2=CCCCC2)c1>>O=C(Nc1cccnc1)c1cnc(OCC(F)(F)F)c(C2CCCCC2)c1 -US20130142737A1,1,CC(CO)CCC(C)(C)C.Cc1cc(CCl)c(O)c(-n2nc3ccccc3n2)c1>>Cc1cc(COCC(C)CCC(C)(C)C)c(O)c(-n2nc3ccccc3n2)c1 -US20110082111A1,2,CN1CCC[C@H](N)C1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)N[C@H]2CCCN(C)C2)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(F)(F)C(=O)N2C -US20100113780A1,1,CCCc1nc(CC)c(Br)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.Cc1cc(C)nc(O)c1>>CCCc1nc(CC)c(Oc2cc(C)cc(C)n2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US20090176850A1,3,CON(C)C(=O)CCc1cccc(Br)c1.C[Mg+]>>CC(=O)CCc1cccc(Br)c1 -US20080114005A1,1,CCCc1nn(C)c2c(=O)n(CCCBr)c(C)nc12.CCOC(=O)C(C)(C)Sc1ccc(N)cc1>>CCCc1nn(C)c2c(=O)n(CCCNc3ccc(SC(C)(C)C(=O)OCC)cc3)c(C)nc12 -US08415486B2,2,CC(C(=O)NC(C(=O)N1CCC2NCC(OCc3ccc(F)cc3)C21)C(C)(C)C)N(C)C(=O)OCc1ccccc1.O=C=NCc1ccccc1>>CC(C(=O)NC(C(=O)N1CCC2C1C(OCc1ccc(F)cc1)CN2C(=O)NCc1ccccc1)C(C)(C)C)N(C)C(=O)OCc1ccccc1 -US07649001B2,4,BrCCCCCBr.Nc1ccc(C(F)(F)F)c2ccccc12>>FC(F)(F)c1ccc(N2CCCCC2)c2ccccc12 -US06348612B1,7,CNC(=O)C(=O)C(C)(C)C>>CNC(=O)[C@H](O)C(C)(C)C -US20120220590A1,1,C=CCOc1cc(Oc2ccc(C=O)cc2)cc(C(=O)OC)c1.Cc1c(N)cccc1[N+](=O)[O-]>>C=CCOc1cc(Oc2ccc(CNc3cccc([N+](=O)[O-])c3C)cc2)cc(C(=O)OC)c1 -US06541263B2,9,C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO>>C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO -US20130324576A1,2,Cc1n[nH]c(C)c1S(=O)(=O)Cl.Fc1cc(Cl)ccc1OC1CCNCC1>>Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2F)CC1 -US04299829,2,CCOC(=O)Cc1csc(N)n1.O=CO>>CCOC(=O)Cc1csc(NC=O)n1 -US20070021443A1,1,CS(=O)(=O)O[C@H]1CCO[C@@H](c2ccccc2)C1.[N-]=[N+]=[N-]>>[N-]=[N+]=N[C@@H]1CCO[C@@H](c2ccccc2)C1 -US05763450,2,CC(=O)Nc1cccc(I)c1.O=C(Cl)C1CC1>>CC(=O)N(C(=O)C1CC1)c1cccc(I)c1 -US09051333B2,6,CC(C)(C)OC(=O)N1CCC(Cc2ccc(OCc3ccc(C(F)(F)F)cc3)cc2)CC1>>FC(F)(F)c1ccc(COc2ccc(CC3CCNCC3)cc2)cc1 -US20140088121A1,2,CN(C)c1cc2c(cc1Sc1nc3c(N)ncnc3n1CCCN)OCO2.O=S(=O)(Cl)C1CC1>>CN(C)c1cc2c(cc1Sc1nc3c(N)ncnc3n1CCCNS(=O)(=O)C1CC1)OCO2 -US20080194617A1,2,CCCCCS(N)(=O)=O.Cc1cnc2c(ccn2-c2c(/C=C/C(=O)O)c(C)nn2C)c1>>CCCCCS(=O)(=O)NC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2cc(C)cnc21 -US20120094972A1,1,CC1(C)CNc2cc(N3CCOCC3)cnc21.Cc1c(-c2ccccn2)nc2c(C)ccc(F)c2c1Cl>>Cc1c(-c2ccccn2)nc2c(C)ccc(F)c2c1N1CC(C)(C)c2ncc(N3CCOCC3)cc21 -US20120178765A1,7,COC(=O)c1cc(OCc2ccccc2C)cc(C(=O)O)c1>>COC(=O)c1cc(CO)cc(OCc2ccccc2C)c1 -US20110130365A1,6,COC(=O)[C@H](CC1CCCC1)n1cc(C(F)(F)F)ccc1=O>>O=C(O)[C@H](CC1CCCC1)n1cc(C(F)(F)F)ccc1=O -US20150152094A1,6,COC(=O)c1cc(-c2nnc(-c3cccc(S(C)(=O)=O)c3)o2)n(-c2ccccc2Cl)n1>>CS(=O)(=O)c1cccc(-c2nnc(-c3cc(C(=O)O)nn3-c3ccccc3Cl)o2)c1 -US07902367B2,1,CC(C)(C)OC(=O)N1CCCCC(CO)C1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCCCC(CN2C(=O)c3ccccc3C2=O)C1 -US20100009969A1,2,C1COCCN1.O=C(O)C1Cc2nc(-c3ccc(OCCCCl)cc3)sc2C1>>O=C(C1Cc2nc(-c3ccc(OCCCCl)cc3)sc2C1)N1CCOCC1 -USH0001759,1,CC(C)(C)[Si](C)(C)OCCBr.CCc1ccc(C=O)c(O)c1>>CCc1ccc(C=O)c(OCCO[Si](C)(C)C(C)(C)C)c1 -US20150031686A1,1,BrCCc1ccc(Br)s1.COc1cc(N)ccc1-c1cnco1>>COc1cc(NCCc2ccc(Br)s2)ccc1-c1cnco1 -US20040220237A1,7,COC(=O)Cc1ccc(Oc2ccc(C(F)(F)F)cc2[N+](=O)[O-])cc1>>COC(=O)Cc1ccc(Oc2ccc(C(F)(F)F)cc2N)cc1 -US20130131035A1,1,Brc1cccc(Br)c1.Fc1ccc(OC2CNC2)cc1>>Fc1ccc(OC2CN(c3cccc(Br)c3)C2)cc1 -US20150005286A1,1,CC1=C(c2cccc(OC3CCCCO3)c2)C(c2ccc(I)cc2)Oc2ccc(OC3CCCCO3)cc21.OCCO>>CC1=C(c2cccc(OC3CCCCO3)c2)C(c2ccc(OCCO)cc2)Oc2ccc(OC3CCCCO3)cc21 -US20120208819A1,3,CC(C)(C)OC(=O)NCc1ccc(B(O)O)cc1.Nc1ncnc2c1c(I)cn2S(=O)(=O)c1ccccc1>>CC(C)(C)OC(=O)NCc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1 -US07649093B2,3,COCOc1c(Br)c(C)cc2cc(OC)ccc12.OB(O)c1ccccc1>>COCOc1c(-c2ccccc2)c(C)cc2cc(OC)ccc12 -US20050020616A1,6,Cc1nc2cc3c(cc2n1C)C1CCC3CN(C(=O)OC(C)(C)C)C1>>Cc1nc2cc3c(cc2n1C)C1CCC3CNC1 -US20050197350A1,9,COC(=O)c1cccc(C(=O)N[C@H]2CC[C@@H](Nc3cc(C)c4ccccc4n3)CC2)c1.N>>Cc1cc(N[C@@H]2CC[C@H](NC(=O)c3cccc(C(N)=O)c3)CC2)nc2ccccc12 -US04740518,1,C=[N+]=[N-].COC1=Cc2ccccc2C(=CC(=O)O)c2ccsc21>>COC(=O)C=C1c2ccccc2C=C(OC)c2sccc21 -US04585788,9,COC(=O)Cc1ccc2c(c1)C(Br)c1ccccc1CO2>>COC(=O)Cc1ccc2c(c1)Cc1ccccc1CO2 -US20150025056A1,2,COC(=O)[C@H]1CN(/C(=N/C#N)N2CCCCC2)CC[C@@H]1C(=O)N1CCN(c2ccc(C#N)cc2C)CC1.NO>>Cc1cc(C#N)ccc1N1CCN(C(=O)[C@H]2CCN(/C(=N/C#N)N3CCCCC3)C[C@@H]2C(=O)NO)CC1 -US20140114068A1,7,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NC(=O)c1cccc[n+]1[O-]>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NC(=O)c1cccc[n+]1[O-] -US20140271662A1,3,Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1B(O)O.Clc1ccc(C2(c3ccc(Br)cc3)CCNCC2)cc1>>Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1-c1ccc(C2(c3ccc(Cl)cc3)CCNCC2)cc1 -US20150005315A1,6,COc1cc(C(=O)O)ccc1Oc1cccc(C)c1>>Cc1cccc(Oc2ccc(C(=O)O)cc2O)c1 -US20090203697A1,8,C=CCC(=O)N1[C@@H](CO)CCC[C@H]1c1ccc(F)cc1>>C=CCC(=O)N1[C@@H](C=O)CCC[C@H]1c1ccc(F)cc1 -US20090181945A1,3,C[Mg+].O=C1C[C@@H](c2ccc(F)cc2)N2C(=O)CCC[C@@H]2C1>>C[C@]1(O)C[C@@H](c2ccc(F)cc2)N2C(=O)CCC[C@@H]2C1 -US07064124B2,7,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccc(F)cc3)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)Nc3ccc(F)cc3)c2)=C(C)C1=O -US20030162777A1,2,FC(F)(F)COc1ccccc1N1CCN(CC2CCc3ccccc3N2)CC1.O=C(Cl)CCOCc1ccccc1>>O=C(CCOCc1ccccc1)N1c2ccccc2CCC1CN1CCN(c2ccccc2OCC(F)(F)F)CC1 -US08901156B2,9,COC(=O)c1ccc(C=O)s1.NO>>COC(=O)c1ccc(C=NO)s1 -US08247562B2,1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2ccnc(Cl)n2)cc1.NCCCN1CCCCC1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2ccnc(NCCCN3CCCCC3)n2)cc1 -US20050222151A1,2,CC(C)N1CCNCC1.O=C(O)c1cccnc1Cl>>CC(C)N1CCN(C(=O)c2cccnc2Cl)CC1 -US04009170,1,NNC1=NCCc2ccccc21.O=C1CCCCC1>>c1ccc2c(c1)CCN=C2NN=C1CCCCC1 -US20130109710A1,7,COC(=O)C1CC(C)(C)CC2(CCCC2)C1=O>>COC(=O)C1CC(C)(C)CC2(CCCC2)C1O -US20050154185A1,6,O=C(NC(CNC(=O)c1ccc2c(cnn2CCCNc2nccn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1)C(=O)O)OCc1ccccc1>>NC(CNC(=O)c1ccc2c(cnn2CCCNc2nccn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1)C(=O)O -US20090192136A1,2,N#Cc1cc(C(F)(F)F)ccc1N1CCNCC1.O=C(Cl)c1cc([N+](=O)[O-])ccc1N1CCOCC1>>N#Cc1cc(C(F)(F)F)ccc1N1CCN(C(=O)c2cc([N+](=O)[O-])ccc2N2CCOCC2)CC1 -US04407756,7,O=C1c2ccccc2C(=O)c2c1cccc2[N+](=O)[O-]>>Nc1cccc2c1C(=O)c1ccccc1C2=O -US06124283,2,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.O=C(Cl)c1ccc(F)cc1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc(F)cc2)CC3)CC1 -US20060211678A1,1,CC(C)(C)OC(=O)N1CC=C(c2cc3c(Cl)ncnc3[nH]2)CC1.Nc1cnn(CCc2ccccc2)c1>>CC(C)(C)OC(=O)N1CC=C(c2cc3c(Nc4cnn(CCc5ccccc5)c4)ncnc3[nH]2)CC1 -US04113858,6,CC(C)(C)OC(=O)N[C@@H](CCC(N)=O)C(=O)O>>NC(=O)CC[C@H](N)C(=O)O -US20060128724A1,3,CC1(C)OB(c2cn[nH]c2)OC1(C)C.Nc1ncc(Br)cc1OC1CCCCc2ccc(F)cc21>>Nc1ncc(-c2cn[nH]c2)cc1OC1CCCCc2ccc(F)cc21 -US05270308,8,CC1(C)N=C(c2ccccn2)c2cc(C#N)ccc2O1.O=C(OO)c1cccc(Cl)c1>>CC1(C)N=C(c2cccc[n+]2[O-])c2cc(C#N)ccc2O1 -US06310070B1,2,CC(C)(C)c1ccc(Cn2cnc(N)c2C(N)=O)cc1.O=C(Cl)c1cccc(F)c1>>CC(C)(C)c1ccc(Cn2cnc(NC(=O)c3cccc(F)c3)c2C(N)=O)cc1 -US20090054471A1,1,Clc1ncnc2nn3ccccc3c12.Nc1ccc(F)c(Cl)c1>>Fc1ccc(Nc2ncnc3nn4ccccc4c23)cc1Cl -US06380288B1,1,NNC(=O)c1ccccc1.O=C(c1ccccc1)c1ccccc1>>O=C(NN=C(c1ccccc1)c1ccccc1)c1ccccc1 -US04312876,1,CCOC(=O)N1CC[C@@H](O)[C@H](c2ccccc2)C1.Oc1cccc(F)c1>>CCOC(=O)N1CC[C@H](Oc2cccc(F)c2)[C@H](c2ccccc2)C1 -US07320993B1,2,NCCCCNC(=O)C(c1ccccc1)c1ccccc1.O=C(O)C=Cc1cccnc1>>O=C(C=Cc1cccnc1)NCCCCNC(=O)C(c1ccccc1)c1ccccc1 -US06451960B1,1,O=C(c1ccccc1)c1ccc(OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CO)cc1.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(c1ccccc1)c1ccc(OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)COc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])cc1 -US03984563,1,CN1C(=N)C(C)(C)c2ccccc21.O=C(Cl)c1ccc(Cl)cc1>>CN1C(=NC(=O)c2ccc(Cl)cc2)C(C)(C)c2ccccc21 -US20140171431A1,6,COC(=O)CN(C)Cc1nnc(Cn2c(SCc3ccc(F)cc3)nc(=O)c3c2CCC3)n1Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>CN(CC(=O)O)Cc1nnc(Cn2c(SCc3ccc(F)cc3)nc(=O)c3c2CCC3)n1Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US20060217416A1,1,C[C@H](NC(=O)c1nc(Br)c2ccccc2c1O)C(=O)O.Sc1ccc(Cl)cc1>>C[C@H](NC(=O)c1nc(Sc2ccc(Cl)cc2)c2ccccc2c1O)C(=O)O -US20070244125A1,2,CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)O)cc3c2)CC1.CNCc1ccccc1>>CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N(C)Cc4ccccc4)cc3c2)CC1 -US20140005213A1,1,CC(C)(C)OC(=O)N[C@H]1CCN([C@H](c2ccc(NN)nc2)C(F)(F)F)C1.COc1cc(F)cc2ccc(C=O)nc12>>COc1cc(F)cc2ccc(/C=N/Nc3ccc([C@@H](N4CC[C@H](NC(=O)OC(C)(C)C)C4)C(F)(F)F)cn3)nc12 -US06025379,1,COc1cc(-c2nc3ccc(O)cc3n2Cc2ccccc2C(F)(F)F)cc(OC)c1OC.ClCCN1CCCCC1>>COc1cc(-c2nc3ccc(OCCN4CCCCC4)cc3n2Cc2ccccc2C(F)(F)F)cc(OC)c1OC -US20120010186A1,6,CCOC(=O)Cn1nnc(-c2cnc(N3CC4CN(C(=O)OC(C)(C)C)CC4C3)s2)n1>>CCOC(=O)Cn1nnc(-c2cnc(N3CC4CNCC4C3)s2)n1 -US07544704B2,3,C#Cc1c(-c2ccccc2)noc1C.Cc1c[nH]nc1I>>Cc1c[nH]nc1C#Cc1c(-c2ccccc2)noc1C -US07960369B2,1,COC(=O)CCc1ccc(O)cc1.Cc1cccc(C)c1Cc1cccc(CO)c1>>COC(=O)CCc1ccc(OCc2cccc(Cc3c(C)cccc3C)c2)cc1 -US20070105819A1,3,O=C(NN1CCCCC1)c1ccc2c(c1)N=C(Cl)c1ccccc1S2.[Zn+]c1cccc(Br)c1>>O=C(NN1CCCCC1)c1ccc2c(c1)N=C(c1cccc(Br)c1)c1ccccc1S2 -US20050070582A1,6,Cc1cc(C)cc(Oc2ccc(C(=O)O)cc2S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1cc(C)cc(Oc2ccc(C(=O)O)cc2S(=O)(=O)N2CCNCC2)c1 -US20100209345A1,6,COC(=O)Cc1c(-c2ccc(OCCF)cc2)nc2ccc(Cl)cn12>>O=C(O)Cc1c(-c2ccc(OCCF)cc2)nc2ccc(Cl)cn12 -US20100272680A1,2,C[C@@H]1OC(=O)N(C2CCNCC2)C1=O.O=C(O)c1nc2c(C(F)(F)F)cc(Br)cn2c1Cl>>C[C@@H]1OC(=O)N(C2CCN(C(=O)c3nc4c(C(F)(F)F)cc(Br)cn4c3Cl)CC2)C1=O -US20120291159A1,1,Clc1ncccn1.Nc1cccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c1>>FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(c2cccc(Nc3ncccn3)c2)=NO1 -US20040116464A1,3,CN(C)C=O.CN(CC(O)c1ccc(Br)cc1)C(=O)OC(C)(C)C>>CN(CC(O)c1ccc(C=O)cc1)C(=O)OC(C)(C)C -US08247429B2,2,CC(=O)OC(C)=O.Cn1cc2c3c(c(F)cc2n1)CCC3=CCN>>CC(=O)NCC=C1CCc2c(F)cc3nn(C)cc3c21 -US20130005716A1,8,COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)c2c1OC1(CCCC1)O2.O=C(OO)c1cccc(Cl)c1>>COc1ccc(C(=O)Cc2c(Cl)c[n+]([O-])cc2Cl)c2c1OC1(CCCC1)O2 -US20150152048A1,6,COC(=O)c1ccc(NC(=O)[C@@H]2C[C@H](N3CCN(Cc4ccccc4)CC3)CN2C(=O)[C@@H]2CC[C@H](CNC(=O)OC(C)(C)C)CC2)cc1>>COC(=O)c1ccc(NC(=O)[C@@H]2C[C@H](N3CCNCC3)CN2C(=O)[C@@H]2CC[C@H](CNC(=O)OC(C)(C)C)CC2)cc1 -US09156852B2,2,CCN1CCN(Cc2ccc(Nc3nccc4c(N)c(C)ccc34)cc2C(F)(F)F)CC1.O=C(O)c1csc2c(NC3CC3)ncnc12>>CCN1CCN(Cc2ccc(Nc3nccc4c(NC(=O)c5csc6c(NC7CC7)ncnc56)c(C)ccc34)cc2C(F)(F)F)CC1 -US07858796B2,2,NC(=O)c1cc(-c2ccccc2)cc2c(C3CCNCC3)c[nH]c12.O=S(=O)(Cl)CCCCl>>NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)c[nH]c12 -US20130018064A1,2,CC(C)(C)C(=O)Cl.Cc1ccccc1-c1ccc2nc(N)ccc2c1>>Cc1ccccc1-c1ccc2nc(NC(=O)C(C)(C)C)ccc2c1 -US20030162795A1,3,Cc1cc2cc(Nc3ccnc4cc(Br)sc34)ccc2[nH]1.Cc1csc(B(O)O)c1>>Cc1csc(-c2cc3nccc(Nc4ccc5[nH]c(C)cc5c4)c3s2)c1 -US05130313,1,Fc1ccc(N2CCN(CCCCl)CC2)cc1.O=S1(=O)Nc2cccc3c2N1CCC3>>O=S1(=O)N(CCCN2CCN(c3ccc(F)cc3)CC2)c2cccc3c2N1CCC3 -US06121265,1,Nc1cc([N+](=O)[O-])c(F)cc1F.c1c[nH]cn1>>Nc1cc([N+](=O)[O-])c(-n2ccnc2)cc1F -US20040063720A1,1,N#Cc1cnc(Cl)s1.Nc1cc(N2CCCC(NC(=O)C(F)(F)F)C2)ncn1>>N#Cc1cnc(Nc2cc(N3CCCC(NC(=O)C(F)(F)F)C3)ncn2)s1 -US20150133453A1,2,NC(=O)c1cccn1N.O=C(Cl)c1ccc(Br)cc1>>NC(=O)c1cccn1NC(=O)c1ccc(Br)cc1 -US04283381,2,Nc1c(I)c(C(=O)O)c(I)c(C(=O)O)c1I.O=C(Cl)CCl>>O=C(CCl)Nc1c(I)c(C(=O)O)c(I)c(C(=O)O)c1I -US20080249130A1,7,CCOC(=O)c1cn2cc([N+](=O)[O-])ccc2n1>>CCOC(=O)c1cn2cc(N)ccc2n1 -US20070244125A1,1,COC1CCN(C(=O)c2cc3cc(C(=O)N4CCN(C(C)C)CC4)ccc3[nH]2)CC1.OB(O)c1cccc(Cl)c1>>COC1CCN(C(=O)c2cc3cc(C(=O)N4CCN(C(C)C)CC4)ccc3n2-c2cccc(Cl)c2)CC1 -US20100069629A1,2,COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccc(C(=O)O)cc3F)cn2)cc1.NCCc1cccnc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccc(C(=O)NCCc4cccnc4)cc3F)cn2)cc1 -US06399614B1,1,Nc1ccccc1OC(F)(F)F.OCCBr>>OCCNc1ccccc1OC(F)(F)F -US07414060B2,1,COCCn1ccc(NC(=O)c2nc(C)ccc2N)n1.Fc1cccc(Br)c1>>COCCn1ccc(NC(=O)c2nc(C)ccc2Nc2cccc(F)c2)n1 -US20040242572A1,2,NCCC1CCC(CN2CCCC2)CC1.O=C(O)c1ccc(-c2ccc(Cl)cc2)cc1>>O=C(NCCC1CCC(CN2CCCC2)CC1)c1ccc(-c2ccc(Cl)cc2)cc1 -US07608621B2,3,CC(C)c1nn(Cc2ccc(Br)cc2)c(=O)c(C(=O)NCC(=O)O)c1O.CN1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cn2)CC1>>CC(C)c1nn(Cc2ccc(-c3ccc(N4CCN(C)CC4)nc3)cc2)c(=O)c(C(=O)NCC(=O)O)c1O -US20120309738A1,7,COC[C@@H]1CCCN1c1cc(NC(=S)Nc2cc(CNC(=O)C3(C(F)(F)F)CC3)ccc2Cl)c([N+](=O)[O-])cc1Cl>>COC[C@@H]1CCCN1c1cc(NC(=S)Nc2cc(CNC(=O)C3(C(F)(F)F)CC3)ccc2Cl)c(N)cc1Cl -US06069176,6,COc1cccc([C@H]2CCC[C@H](NCc3ccccc3)C2)c1>>COc1cccc([C@H]2CCC[C@H](N)C2)c1 -US05294638,1,CC1(C)[C@H]2CC[C@@H](CCCl)[C@@H]1C2.OCCCCO>>CC1(C)[C@H]2CC[C@@H](CCOCCCCO)[C@@H]1C2 -US04508730,1,CCOC(=O)CCCN.Cc1c2c(cn1C)N(C)C(=O)C(O)N=C2c1ccccc1Cl>>CCOC(=O)CCCNC1N=C(c2ccccc2Cl)c2c(cn(C)c2C)N(C)C1=O -US20140249137A1,2,CN(C)CCN.O=S(=O)(Cl)c1ccc(Br)s1>>CN(C)CCNS(=O)(=O)c1ccc(Br)s1 -US20120302524A1,3,O=C(Nc1nnc(-c2ccco2)o1)c1cc(Br)cs1.OB(O)c1ccc(-c2ccccc2)cc1>>O=C(Nc1nnc(-c2ccco2)o1)c1cc(-c2ccc(-c3ccccc3)cc2)cs1 -US08119627B2,1,NCc1ccccc1Oc1ccc(Cl)cc1.O=C1CCN(C(=O)C2CCCCC2)CC1>>O=C(C1CCCCC1)N1CCC(NCc2ccccc2Oc2ccc(Cl)cc2)CC1 -US20150141409A1,1,BrCCCCCCN1CCOCC1.O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1>>O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)OCCCCCCN1CCOCC1)c1ccc(Cl)cc1 -US04315016,1,O=C(CBr)c1ccc(Cl)cc1.c1nc[nH]n1>>O=C(Cn1cncn1)c1ccc(Cl)cc1 -US05155113,2,CCCOc1ccc(C(=O)Cl)cc1.O=c1cc(O)cc[nH]1>>CCCOc1ccc(C(=O)Oc2cc[nH]c(=O)c2)cc1 -US08748426B2,2,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O.COc1cccc(N=C=S)c1>>COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=S)Nc4cccc(OC)c4)cc3)cc2C1=O -US20120157433A1,1,CC(C)(C)OC(=O)N1C[C@H](C#N)C[C@H]1CO.CI>>COC[C@@H]1C[C@@H](C#N)CN1C(=O)OC(C)(C)C -US07544703B2,1,C1COCCN1.CC(C)(C)c1ccc(NC(=O)c2cccnc2SC(NC(=O)CCl)c2ccncc2)cc1>>CC(C)(C)c1ccc(NC(=O)c2cccnc2SC(NC(=O)CN2CCOCC2)c2ccncc2)cc1 -US04894374,1,C1CC2(CCN1)OCCO2.CS(=O)(=O)c1ccc(F)cc1>>CS(=O)(=O)c1ccc(N2CCC3(CC2)OCCO3)cc1 -US20060264460A1,1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1ccccc1O>>N#Cc1cnc2ccc(NCc3ccccc3O)cc2c1Nc1ccc(F)c(Cl)c1 -US08455495B2,3,Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1.Cn1c(=O)c(Br)cc2cnnc(-c3ccc(F)cc3F)c21>>Cc1ccc(C(=O)NC2CC2)cc1-c1cc2cnnc(-c3ccc(F)cc3F)c2n(C)c1=O -US08901141B2,1,CCCC(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl.CI>>CCCC(OC)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl -US20080269210A1,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.Nc1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1>>Nc1cccc(-c2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)c1 -US20140206660A1,9,CC(C)(C)OC(=O)N1CC[C@H](CN=[N+]=[N-])[C@H](F)C1>>CC(C)(C)OC(=O)N1CC[C@H](CN)[C@H](F)C1 -US20100075959A1,2,CNCc1ccc(C)nc1.COc1ccc(-c2ccccc2)c2sc(NC(=O)OC(C)(C)C)nc12>>COc1ccc(-c2ccccc2)c2sc(NC(=O)N(C)Cc3ccc(C)nc3)nc12 -US05733914,1,ClCc1ccncc1.Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)[nH]c2n1>>Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(Cc3ccncc3)c2n1 -US20140065103A1,6,COC(=O)c1sc(C#CC(F)(F)F)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C>>CC(C)N(C(=O)[C@@H]1CC[C@@H](C)CC1)c1cc(C#CC(F)(F)F)sc1C(=O)O -US20060128790A1,1,CCOC(=O)C1(C=O)CCC1.COc1c(C)cc(N)c(C)c1C>>CCOC(=O)C1(CNc2cc(C)c(OC)c(C)c2C)CCC1 -US08022062B2,6,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCCCN3C(=O)c4ccccc4C3=O)c2CC1>>CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCCCN)c2CC1 -US20050026836A1,6,CCOC(=O)C1(N(C)S(=O)(=O)c2ccc3c(Cl)cnc(NC(=N)N)c3c2)CCCC1>>CN(C1(C(=O)O)CCCC1)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1 -US20090099162A2,7,CCOC(=O)C=Cc1ccc(C#N)cc1>>CCOC(=O)CCc1ccc(C#N)cc1 -US20080318923A1,1,CN(C)C(=O)[C@@H]1C[C@@H](O)CN1.COc1cc(CO[Si](C)(C)C(C)(C)C)ccc1C1(O)C(=O)Nc2ccc(Cl)cc21>>COc1cc(CO[Si](C)(C)C(C)(C)C)ccc1C1(N2C[C@H](O)C[C@H]2C(=O)N(C)C)C(=O)Nc2ccc(Cl)cc21 -US20040132733A1,1,BrCc1ccccc1.COC(=O)C[C@H]1Nc2ccccc2NC1=O>>COC(=O)C[C@@H]1C(=O)Nc2ccccc2N1Cc1ccccc1 -US08058300B2,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)O[C@@H](C)c1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC(=O)O[C@@H](C)c4ccccc4)cc3)cc2)CC1 -US09085578B2,1,CC(C)(C)OC(=O)NCCBr.Oc1ccc(Br)nc1>>CC(C)(C)OC(=O)NCCOc1ccc(Br)nc1 -US06313160B1,2,CC(=O)OC(C)=O.COc1ccc2c(c1)OC(CN)=C(c1ccccc1)O2>>COc1ccc2c(c1)OC(CNC(C)=O)=C(c1ccccc1)O2 -US08927588B2,2,CCc1[nH]c(C(=O)N[C@H]2CCN(c3ncc(C(=O)O)s3)C[C@H]2OC)nc1Cl.CNC>>CCc1[nH]c(C(=O)N[C@H]2CCN(c3ncc(C(=O)N(C)C)s3)C[C@H]2OC)nc1Cl -US20100297075A1,7,COc1cccc(C2=C(c3cn4c5c(cccc35)CCC4)C(=O)NC2=O)c1>>COc1cccc([C@@H]2C(=O)NC(=O)[C@H]2c2cn3c4c(cccc24)CCC3)c1 -US08217032B2,3,COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(OS(=O)(=O)C(F)(F)F)ccc2c1.OB(O)c1ccc(F)cc1F>>COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(F)cc3F)ccc2c1 -US04341756,4,CC1(C)OCC=CCO1.OO>>CC1(C)OCC2OC2CO1 -US20070135415A1,6,CC(=O)OCc1cccc(-c2[nH]c3cc(NC(=O)[C@@H]4C[C@H]4c4ccccc4)cc4c3c2C=NNC4=O)c1>>O=C1NN=Cc2c(-c3cccc(CO)c3)[nH]c3cc(NC(=O)[C@@H]4C[C@H]4c4ccccc4)cc1c23 -US20110237581A1,6,CC1CN(C(=O)OCc2ccccc2)CCN1C(=O)OC(C)(C)C>>CC1CNCCN1C(=O)OC(C)(C)C -US20120149721A1,2,COCC(=O)Cl.Cc1[nH]c2c(-c3ccc(F)cc3OCC3CC3)ncnc2c1C(=O)N[C@@H]1CC[C@@H](N)CC1>>COCC(=O)N[C@@H]1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4ccc(F)cc4OCC4CC4)ncnc23)CC1 -US20090192149A1,2,CC(C)(C)[Si](C)(C)OC(C(=O)O)c1ccc(C#N)cc1.OCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC(C)(C)[Si](C)(C)OC(C(=O)OCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)c1ccc(C#N)cc1 -US20030078251A1,2,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc(CC(=O)O)cc3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc(CC(=O)O)cc3)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC -US20020007071A1,1,CC(C)(C)OC(=O)N1CCC(CCCn2c(COc3ccc(Cl)cc3)nc3c(OCCCBr)cccc32)CC1.CC1CCNCC1>>CC1CCN(CCCOc2cccc3c2nc(COc2ccc(Cl)cc2)n3CCCC2CCN(C(=O)OC(C)(C)C)CC2)CC1 -US20070010537A1,2,COC(=O)c1ccc(S(=O)(=O)Cl)o1.c1ccc2c(c1)CCCN2>>COC(=O)c1ccc(S(=O)(=O)N2CCCc3ccccc32)o1 -US07553969B1,6,CC(C)C(C(=O)NC(Cc1ccc(O)c(C(C)(C)C)c1)C1NC(=O)NC1=O)N(C)C(=O)OCc1ccccc1>>CNC(C(=O)NC(Cc1ccc(O)c(C(C)(C)C)c1)C1NC(=O)NC1=O)C(C)C -US20040097728A1,1,COC(=O)Cl.NNCCO>>COC(=O)N(N)CCO -US20120165298A1,1,CN(C)CC[C@@H](N)CSc1ccccc1.NS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1>>CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(S(N)(=O)=O)cc1C(F)(F)F -US05710149,7,O=[N+]([O-])c1cccc2c1OCCO2>>Nc1cccc2c1OCCO2 -US20140010760A1,1,O=C1c2ccccc2C(=O)N1CCCBr.O=[N+]([O-])c1ncc[nH]1>>O=C1c2ccccc2C(=O)N1CCCn1ccnc1[N+](=O)[O-] -US20080051405A1,7,CN1CCC(Oc2cccc(C#N)n2)CC1>>CN1CCC(Oc2cccc(CN)n2)CC1 -US05210092,1,CCCC(=O)Nc1nccc(C)c1[N+](=O)[O-].N#Cc1cc(Cl)cn1-c1ccc(CBr)cc1>>CCCC(=O)N(Cc1ccc(-n2cc(Cl)cc2C#N)cc1)c1nccc(C)c1[N+](=O)[O-] -US06693200B2,3,CC(C)OCc1ccc(Br)cc1.C[Si](C)(C)CCOC(=O)Nc1ccc(CCl)cc1>>CC(C)OCc1ccc(Cc2ccc(NC(=O)OCC[Si](C)(C)C)cc2)cc1 -US20120202856A1,3,CC1(C)COB(c2cc(Cl)c(N)c([N+](=O)[O-])c2)OC1.Fc1cccc(F)c1Br>>Nc1c(Cl)cc(-c2c(F)cccc2F)cc1[N+](=O)[O-] -US08450336B2,6,COC(=O)C(COC(F)F)N(Cc1ccccc1)Cc1ccccc1>>O=C(O)C(COC(F)F)N(Cc1ccccc1)Cc1ccccc1 -US06093838,6,COc1ccc(N(c2cc3c(c(C(C)C)c2C)OCC3(C)C)C(C)C)cc1>>Cc1c(N(c2ccc(O)cc2)C(C)C)cc2c(c1C(C)C)OCC2(C)C -US20060257987A1,6,COC(=O)CCc1ccc(OCCC(C)Oc2ccc(OC(F)(F)F)cc2C(=O)c2cccs2)cc1C>>Cc1cc(OCCC(C)Oc2ccc(OC(F)(F)F)cc2C(=O)c2cccs2)ccc1CCC(=O)O -US20120108574A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4n(c3-c3ccccc3)-c3cccnc3Nc3ccccc3-4)cc2)CCC1>>NC1(c2ccc(-c3nc4n(c3-c3ccccc3)-c3cccnc3Nc3ccccc3-4)cc2)CCC1 -US06376499B1,7,CCOC(=O)c1cc(C)nc(OC)c1[N+](=O)[O-]>>COc1nc(C)cc(CO)c1[N+](=O)[O-] -US08022224B2,10,Cc1cc(Br)ccc1F.O=C1CCC(=O)N1Br>>Fc1ccc(Br)cc1CBr -US08327467B2,6,CN(C)c1ccccc1Nc1cc(CCc2ccccc2)ccc1C(=O)OC(C)(C)C>>CN(C)c1ccccc1Nc1cc(CCc2ccccc2)ccc1C(=O)O -US20100311749A1,2,CN1CCNCC1=O.O=C(O)c1cccc(C(F)(F)F)c1Cl>>CN1CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)CC1=O -US20110230487A1,1,C1COCCN1.N#Cc1ccc(Oc2cc(Cl)cc(Cl)c2)c(S(=O)(=O)N2CCC(NC(=O)NCCCl)CC2)c1>>N#Cc1ccc(Oc2cc(Cl)cc(Cl)c2)c(S(=O)(=O)N2CCC(NC(=O)NCCN3CCOCC3)CC2)c1 -US20090186876A1,2,CCOC(=O)c1cnc(N2CCNCC2)c(Cl)c1.COc1ccccc1N=C=O>>CCOC(=O)c1cnc(N2CCN(C(=O)Nc3ccccc3OC)CC2)c(Cl)c1 -US05670675,2,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(O)C(Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C.O=C(Cl)c1ccc(CCl)cc1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(OC(=O)c1ccc(CCl)cc1)C(Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C -US05208247,2,CCCCCCCCCCCCCCOc1ccc(C(=O)NCc2ccccn2)cc1.COc1ccccc1C(=O)Cl>>CCCCCCCCCCCCCCOc1ccc(C(=O)N(Cc2ccccn2)C(=O)c2ccccc2OC)cc1 -US20040110811A1,2,CC1(C)NC(=O)NC1=O.O=S(=O)(Cl)c1cccc2ccccc12>>CC1(C)NC(=O)N(S(=O)(=O)c2cccc3ccccc23)C1=O -US06166006,1,CNCC#N.Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CCl)cc3)c2)cc1>>Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CN(C)CC#N)cc3)c2)cc1 -US05585376,1,Nc1ccccc1F.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1Nc1ccccc1F -US04943569,9,COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)C(C(C)OC(=O)OCc3ccc([N+](=O)[O-])cc3)C2CC(=O)C(C(=O)OCc2ccc([N+](=O)[O-])cc2)C(=O)OC(C)(C)C)cc1>>COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)C(C(C)OC(=O)OCc3ccc([N+](=O)[O-])cc3)C2CC(=O)CC(=O)OCc2ccc([N+](=O)[O-])cc2)cc1 -US20140336108A1,2,COC(=O)c1cc2nccc(Oc3cccc(N)c3)c2s1.Cc1ccoc1C(=O)O>>COC(=O)c1cc2nccc(Oc3cccc(NC(=O)c4occc4C)c3)c2s1 -US20100216746A1,6,CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1C(=O)OC(C)(C)C>>CCOC(=O)c1cc2cc(O)ccc2n1C(=O)OC(C)(C)C -US20130018046A1,3,C#Cc1cncc2nc[nH]c12.Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1I>>Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cncc2nc[nH]c12 -US06252084B1,6,COc1ccc2c(c1)c(CC(N)=O)c(Br)n2Cc1ccccc1>>NC(=O)Cc1c(Br)n(Cc2ccccc2)c2ccc(O)cc12 -US20050065164A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)CNCCC1=O>>CC(C)(C)OC(=O)N1CCC(=O)C(C)(C)C1 -US06605620B1,3,CCOC(=O)c1ccnc(Cl)c1.COc1cc(B(O)O)cc(OC)c1Cl>>CCOC(=O)c1ccnc(-c2cc(OC)c(Cl)c(OC)c2)c1 -US07638521B2,1,COC(=O)c1c[nH]c2ccccc12.Cc1cc(Cl)c2ccccc2n1>>COC(=O)c1cn(-c2cc(C)nc3ccccc23)c2ccccc12 -US20150210697A1,6,COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCC(N(C)C5CC(=O)N(C)C5)CC4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>CN1CC(N(C)C2CCN(c3cc(C#N)cc(Nc4nc(NC5CC5)c5ncc(C#N)n5n4)c3Cl)CC2)CC1=O -US20100144720A1,2,CC(=Cc1ccccc1)CNCCN1CCCCC1.COc1cc(C(=O)O)cc(OC)c1OC>>COc1cc(C(=O)N(CCN2CCCCC2)CC(C)=Cc2ccccc2)cc(OC)c1OC -US05929120,2,CC(C)(C)OC(=O)[C@H](CN)NS(=O)(=O)c1ccccc1.O=C(NCCOCc1ccc(C(=O)O)cc1)OCc1ccccc1>>CC(C)(C)OC(=O)[C@H](CNC(=O)c1ccc(COCCNC(=O)OCc2ccccc2)cc1)NS(=O)(=O)c1ccccc1 -US05698696,2,CC(C)C(=O)Cl.Cc1c(C)c2c(c(C)c1O)C(=O)C(C)(C)O2>>Cc1c(C)c2c(c(C)c1OC(=O)C(C)C)C(=O)C(C)(C)O2 -US20140113882A1,1,COc1cncc2nc(-c3ccnc(Cl)c3)nc(N3CC[C@@H](O)[C@H](O)C3)c12.Nc1ccccc1>>COc1cncc2nc(-c3ccnc(Nc4ccccc4)c3)nc(N3CC[C@@H](O)[C@H](O)C3)c12 -US20140199263A1,4,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(C(=O)NNC(=O)c3cc4c(F)cccc4[nH]3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3nnc(-c4cc5c(F)cccc5[nH]4)o3)cc12 -US20140127103A1,6,CC(C)(C)OC(=O)NC1CCN(CCO)CC1>>NC1CCN(CCO)CC1 -US20150239900A1,3,CC(C)(C)OC(=O)N1CCN(c2ncnc3cc(Cl)c(Br)cc23)CC1.OB(O)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCN(c2ncnc3cc(Cl)c(-c4ccc(Cl)cc4)cc23)CC1 -US20110105470A1,2,O=C(Cl)c1cccc(Cl)c1.O=C1C(=O)c2ccc(Br)cc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccc(Br)cc2C2=C1SCC1(CCN(C(=O)c3cccc(Cl)c3)CC1)O2 -US08048909B2,1,CN.CS(=O)(=O)c1cccc(S(=O)(=O)n2cc(C=O)cc2-c2ccccc2F)c1>>CNCc1cc(-c2ccccc2F)n(S(=O)(=O)c2cccc(S(C)(=O)=O)c2)c1 -US20150239884A1,2,CN1CCC(N)CC1.Nc1ccc(C(=O)O)cc1OC(F)(F)F>>CN1CCC(NC(=O)c2ccc(N)c(OC(F)(F)F)c2)CC1 -US06759408B2,3,CC1(C)OC(=O)Nc2ccc(B(O)O)cc21.N#Cc1cccc(Br)c1>>CC1(C)OC(=O)Nc2ccc(-c3cccc(C#N)c3)cc21 -US20010000513A1,6,COC(=O)CCC(=O)c1ccc(-c2ccc(F)cc2)cc1>>O=C(O)CCC(=O)c1ccc(-c2ccc(F)cc2)cc1 -US20150197509A1,2,NCc1cccc(-c2ccc(C(F)(F)F)cc2)c1.O=C(Cl)CBr>>O=C(CBr)NCc1cccc(-c2ccc(C(F)(F)F)cc2)c1 -US20070232627A1,2,CC(C)c1ccc2c(Nc3cc(C(=O)O)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1.NCc1ccccc1>>CC(C)c1ccc2c(Nc3cc(C(=O)NCc4ccccc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1 -US20030087909A1,3,CSc1ccccc1B(O)O.O=C1C(O)CCCN1c1ccc(Br)cc1F>>CSc1ccccc1-c1ccc(N2CCCC(O)C2=O)c(F)c1 -US20050002859A1,2,COc1ccc2c(c1)c(CC(=O)NCCNC(=O)c1ccc(O)cc1)c(C)n2C(=O)c1ccc(Cl)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc2c(c1)c(CC(=O)NCCNC(=O)c1ccc(OS(=O)(=O)c3ccc(C)cc3)cc1)c(C)n2C(=O)c1ccc(Cl)cc1 -US20020035266A1,6,COC(=O)/C(=C/C1CCCC1)c1ccc(-n2nnnc2C)c(C(F)(F)F)c1>>Cc1nnnn1-c1ccc(/C(=C\C2CCCC2)C(=O)O)cc1C(F)(F)F -US07285558B2,2,CN(C)CCN.Cc1ccc2[nH]cc(Cn3nc4c(c3-c3cc(C(=O)O)cn3C)c(=O)n(C)c(=O)n4CC(C)C)c2c1>>Cc1ccc2[nH]cc(Cn3nc4c(c3-c3cc(C(=O)NCCN(C)C)cn3C)c(=O)n(C)c(=O)n4CC(C)C)c2c1 -US20060041123A1,7,CCOC(=O)/C=C/c1ccc(C(=O)OC)nc1N>>CCOC(=O)CCc1ccc(C(=O)OC)nc1N -US20080269170A1,2,CNC1CCC2(CC1)OCCO2.O=S(=O)(Cl)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1>>CN(C1CCC2(CC1)OCCO2)S(=O)(=O)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1 -US08278328B2,7,Cc1cc(F)c(O)c([N+](=O)[O-])c1>>Cc1cc(N)c(O)c(F)c1 -US20080311113A1,6,COC(=O)C(NS(=O)(=O)c1ccc(-c2ccc(COc3nc4ccccc4cc3C)cc2)cc1)C(C)C>>Cc1cc2ccccc2nc1OCc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc2)cc1 -US20040133008A1,6,Cc1ccc(C(=O)Nc2ccc(N(CCc3ccccn3)C(=O)OC(C)(C)C)cc2)c(N2CCCCC2)n1>>Cc1ccc(C(=O)Nc2ccc(NCCc3ccccn3)cc2)c(N2CCCCC2)n1 -US20150252008A1,6,CC(C)(C)OC(=O)COc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F>>Nc1cnc(-c2ccc(C3CCC3)c(OCC(=O)O)c2F)cn1 -US20100256134A1,1,CCOC(=O)c1cnn2c(Cl)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12.Cc1cscc1N>>CCOC(=O)c1cnn2c(Nc3cscc3C)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12 -US08242280B2,2,CNC.COc1ccccc1-c1nn(COCC[Si](C)(C)C)c2ncc(-c3cccc(C(C(=O)O)N(C)C)c3)cc12>>COc1ccccc1-c1nn(COCC[Si](C)(C)C)c2ncc(-c3cccc(C(C(=O)N(C)C)N(C)C)c3)cc12 -US08236955B2,1,CN1CCN(C(=O)[C@@H]2C[C@H](N)CN2C(=O)OC(C)(C)C)CC1.Fc1ccc(Br)c(F)c1>>CN1CCN(C(=O)[C@@H]2C[C@H](Nc3ccc(F)cc3F)CN2C(=O)OC(C)(C)C)CC1 -US04282028,1,Cc1ccc(C)n1NC(=O)CCl.Cc1nc(CCl)cs1>>Cc1nc(CN(C(=O)CCl)n2c(C)ccc2C)cs1 -US06011044,1,Cc1ccccc1N1CCc2c(Cl)nc3c(OCC(F)(F)F)cccc3c21.NCCCO>>Cc1ccccc1N1CCc2c(NCCCO)nc3c(OCC(F)(F)F)cccc3c21 -US08673903B2,1,CCOC(=O)CCCCBr.COC(=O)c1ccc(CNC2CCc3cccc(OC)c3C2)cc1>>CCOC(=O)CCCCN(Cc1ccc(C(=O)OC)cc1)C1CCc2cccc(OC)c2C1 -US20130109682A1,3,COC(=O)c1ccc(F)c(Br)n1.COc1cc(F)c(B(O)O)c(F)c1>>COC(=O)c1ccc(F)c(-c2c(F)cc(OC)cc2F)n1 -US06987114B1,1,BrCc1ccccc1.CCc1c(Oc2cc(C)cc(C)c2)[nH]c(=O)[nH]c1=O>>CCc1c(Oc2cc(C)cc(C)c2)n(Cc2ccccc2)c(=O)[nH]c1=O -US06251911B1,1,Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12.O=Cc1ccccc1-c1nnn[nH]1>>Clc1cccc(Nc2ncnc3[nH]nc(N=Cc4ccccc4-c4nnn[nH]4)c23)c1 -US08912186B2,2,CCCc1ccc(C(CC(=O)O)CC(=O)O)cc1>>CCCc1ccc(C2CC(=O)OC(=O)C2)cc1 -US05491126,3,C[Sn](C)(C)c1cccc(C(F)(F)F)c1.Cc1cc(Br)c2nc(OCC(F)(F)F)ccc2c1>>Cc1cc(-c2cccc(C(F)(F)F)c2)c2nc(OCC(F)(F)F)ccc2c1 -US20060019958A1,3,O=C1CSC(=O)N1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=Cc1cc(Cl)ccc1O>>O=C1SC(=Cc2cc(Cl)ccc2O)C(=O)N1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20040147612A1,1,N#CCBr.N#CCCc1ccc(O)cc1>>N#CCCc1ccc(OCC#N)cc1 -US20090286974A1,1,Brc1cnc(Br)s1.CC1CNCC(C)N1>>CC1CN(c2ncc(Br)s2)CC(C)N1 -US20080293736A1,2,O=C(O)CCN1CCN(c2cccc(Cl)c2Cl)CC1.O=C1CCc2ccc(CO)cc2N1>>O=C1CCc2ccc(COC(=O)CCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1 -US08822486B2,1,CCOC(=O)CCc1ccc(O)cc1F.COc1cc(CBr)sc1CO[Si](C)(C)C(C)(C)C>>CCOC(=O)CCc1ccc(OCc2cc(OC)c(CO[Si](C)(C)C(C)(C)C)s2)cc1F -US04492692,2,CC(C)COC(=O)Cl.NCCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1>>CC(C)COC(=O)NCCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1 -US20060063760A1,6,COC(=O)/C=C/c1ccc2c(c1)CCC2N(CCc1c[nH]c2ccccc12)S(=O)(=O)c1ccc(NC(C)=O)cc1>>COC(=O)/C=C/c1ccc2c(c1)CCC2N(CCc1c[nH]c2ccccc12)S(=O)(=O)c1ccc(N)cc1 -US20150166505A1,2,CCOC(=O)c1nn(C)c(-c2cnc(OC)cc2OC)c1C.Nc1c(F)cccc1F>>COc1cc(OC)c(-c2c(C)c(C(=O)Nc3c(F)cccc3F)nn2C)cn1 -US04248869,9,COC(=O)c1cc(N)c(C)cc1OC.S=C=S>>COC(=O)c1cc(N=C=S)c(C)cc1OC -US08664220B2,1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CBr)cc3)cc2)CC1.c1ccc(-c2c[nH]nn2)cc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Cn4cc(-c5ccccc5)nn4)cc3)cc2)CC1 -US05863918,7,CCOC(=O)CC1CCCc2c(OC)cccc21>>COc1cccc2c1CCCC2CCO -US08586596B2,1,CCCCI.Nc1cncnc1Br>>CCCCNc1cncnc1Br -US08173650B2,1,COC(C)(C)C1CCN(Cc2nc3c(N4CCOCC4)nc(Cl)nc3n2C)CC1.Nc1ccccc1N>>COC(C)(C)C1CCN(Cc2nc3c(N4CCOCC4)nc(Nc4ccccc4N)nc3n2C)CC1 -US08101612B2,6,COC(=O)c1ccc(C)c(-c2ccc3c(-c4ccc(S(=O)(=O)C(F)(F)F)cc4C)nncc3c2)c1>>Cc1ccc(C(=O)O)cc1-c1ccc2c(-c3ccc(S(=O)(=O)C(F)(F)F)cc3C)nncc2c1 -US20030092712A1,6,COC(=O)c1cc(Br)c(/C=C\C(=O)OC(C)(C)C)c(Br)c1>>COC(=O)c1cc(Br)c(/C=C\C(=O)O)c(Br)c1 -US20140187553A1,3,CC(C)Oc1cccc(B2OC(C)(C)C(C)(C)O2)n1.Cc1ccc(S(=O)(=O)n2cc(I)c3cc(-c4nnc(S(C)(=O)=O)s4)ccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cccc(OC(C)C)n3)c3cc(-c4nnc(S(C)(=O)=O)s4)ccc32)cc1 -US20030120077A1,1,CC(C)(O)CON1C(C)(C)CC(CCCCNc2nc(Cl)nc(NCCCCC3CC(C)(C)N(OCC(C)(C)O)C(C)(C)C3)n2)CC1(C)C.NCCO>>CC(C)(O)CON1C(C)(C)CC(CCCCNc2nc(NCCO)nc(NCCCCC3CC(C)(C)N(OCC(C)(C)O)C(C)(C)C3)n2)CC1(C)C -US20120088809A1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1.CC1Cc2c(OS(=O)(=O)C(F)(F)F)ccc(F)c2O1>>CC1Cc2c(N3CC[C@H](NC(=O)OC(C)(C)C)C3)ccc(F)c2O1 -US20020165275A1,2,NC(c1ccccc1)c1ccccc1.O=[N+]([O-])c1cc(S(=O)(=O)Cl)ccc1Cl>>O=[N+]([O-])c1cc(S(=O)(=O)NC(c2ccccc2)c2ccccc2)ccc1Cl -US20040220188A1,3,COc1ccccc1B(O)O.O=Cc1ccc(Br)s1>>COc1ccccc1-c1ccc(C=O)s1 -US08835428B2,2,COC(=O)[C@@H](N)C(C)C.O=C(Nc1ccccc1)Nc1ccc(-c2noc(C(=O)O)c2-c2ccccc2)cc1>>COC(=O)[C@@H](NC(=O)c1onc(-c2ccc(NC(=O)Nc3ccccc3)cc2)c1-c1ccccc1)C(C)C -US20130072473A1,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCc2c(sc(N)c2-c2nc3cc(Cl)ccc3s2)C1>>CC(=O)Nc1sc2c(c1-c1nc3cc(Cl)ccc3s1)CCN(C(=O)OC(C)(C)C)C2 -US08455646B2,7,CCOC(=O)C(=O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)C(O)c1ccc(C(F)(F)F)cc1 -US07943669B2,6,CCOC(=O)COc1ccc(SCc2cc(C#CCN3CCOCC3)cc(OCC3CC3)c2)cc1C>>Cc1cc(SCc2cc(C#CCN3CCOCC3)cc(OCC3CC3)c2)ccc1OCC(=O)O -US08093302B2,1,CO.Oc1ccc(C2Cc3c(CBr)cc(O)cc3C3CCCC23)cc1>>COCc1cc(O)cc2c1CC(c1ccc(O)cc1)C1CCCC21 -US20100298287A1,1,CCC(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(OC)nc1C.CCI>>CCOC(CC)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(OC)nc1C -US20070249670A1,6,COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C>>COC(=O)[C@@H]1CNCCN1C(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C -US20070149525A1,6,CCC1CC1(NCC(O)C(Cc1cc(F)cc(F)c1)NC(=O)OC(C)(C)C)c1cccc(-n2cccn2)c1>>CCC1CC1(NCC(O)C(N)Cc1cc(F)cc(F)c1)c1cccc(-n2cccn2)c1 -US05629419,7,COC(=O)C[C@@H](SCc1ccccc1)C(=O)O>>COC(=O)C[C@H](CO)SCc1ccccc1 -US04207337,2,COC(=O)CC(C)C(=O)O.C[C@H](N)C(=O)OCc1ccccc1>>COC(=O)CC(C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1 -US20130172317A1,6,COCO[C@@H](Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)OC>>COC(=O)[C@@H](O)Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O -US20150259350A1,3,CC1(C)OB(c2cnn(CCOC3CCCCO3)c2)OC1(C)C.Cn1cc(-c2cnc3nnn(C[C@@H]4CN(c5ncc(Br)cn5)CCO4)c3n2)cn1>>Cn1cc(-c2cnc3nnn(C[C@@H]4CN(c5ncc(-c6cnn(CCOC7CCCCO7)c6)cn5)CCO4)c3n2)cn1 -US06051712,6,CC(C)(C)OC(=O)N1CCC(c2ncc(OCCCOCc3ccccc3)cn2)C(OCc2ccc3ccccc3c2)C1>>c1ccc(COCCCOc2cnc(C3CCNCC3OCc3ccc4ccccc4c3)nc2)cc1 -US20110190276A1,2,CC(=O)Cl.CC(C)(C)[Si](C)(C)CC1CN2CCNCC2CN1>>CC(=O)N1CCN2CC(C[Si](C)(C)C(C)(C)C)NCC2C1 -US20150031686A1,1,COc1cc(N)ccc1-c1cnco1.Cc1cc(C=O)cs1>>COc1cc(NCc2csc(C)c2)ccc1-c1cnco1 -US20090286777A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.C[C@@H](O[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](C=O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COC(=O)/C=C/[C@H]1[C@H](c2ccc(F)cc2)[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1C(=O)OC(C)(C)C -US06703392B2,1,CCI.COc1ccc(CC2c3c(OC)ccc(O)c3CCN2CC(=O)NCc2ccccn2)cc1OC>>CCOc1ccc(OC)c2c1CCN(CC(=O)NCc1ccccn1)C2Cc1ccc(OC)c(OC)c1 -US08518972B2,7,CCOC(=O)c1cc(COC2CCCCO2)no1>>OCc1cc(COC2CCCCO2)no1 -US20050143383A1,6,CN(C)CCNC(=O)c1cccc2nc3ccc4c(OCC(=O)OC(C)(C)C)cccc4c3nc12>>CN(C)CCNC(=O)c1cccc2nc3ccc4c(OCC(=O)O)cccc4c3nc12 -US08431695B2,1,CC(C)(C)[Si](C)(C)OCC1CN(Cc2ccccc2)CCN1.Nc1ncnn2c(C(=O)CCl)ccc12>>CC(C)(C)[Si](C)(C)OCC1CN(Cc2ccccc2)CCN1CC(=O)c1ccc2c(N)ncnn12 -US20030165873A1,9,CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@H](CCC(=O)NCCOCCOCCOCCN=[N+]=[N-])C(=O)OC(C)(C)C)cc1>>CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@H](CCC(=O)NCCOCCOCCOCCN)C(=O)OC(C)(C)C)cc1 -US04363805,1,BrCCCCCCCCBr.[O-]c1ccccc1>>BrCCCCCCCCOc1ccccc1 -US05688815,6,O=c1ccn(CC(O)CO)c(C(O)c2ccccc2)c1OCc1ccccc1>>O=c1ccn(CC(O)CO)c(C(O)c2ccccc2)c1O -US20100075952A1,3,COCC(=O)Nc1cc2c(cc1F)CC(=O)N2.Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCOCC1)CCC2>>COCC(=O)Nc1cc2c(cc1F)C(=Cc1[nH]c3c(c1C)C(=O)N(CCN1CCOCC1)CCC3)C(=O)N2 -US20070015774A1,6,CN(C)CC[C@H](NC(=O)OC(C)(C)C)C(N)=O>>CN(C)CC[C@H](N)C(N)=O -US20130310374A1,7,CC(C)(C#N)c1ccc([N+](=O)[O-])cn1>>CC(C)(C#N)c1ccc(N)cn1 -US05739116,6,CCOC(=O)C(CC)Oc1ccccc1C(C)=O>>CCC(Oc1ccccc1C(C)=O)C(=O)O -US08034811B2,2,NCCCO.O=C(O)c1cc(CNc2ccccc2C(=O)NOCC2CCCC2)ccc1F>>O=C(NCCCO)c1cc(CNc2ccccc2C(=O)NOCC2CCCC2)ccc1F -US08013001B2,1,FC(F)(F)c1cccnc1Cl.Ic1cn[nH]c1>>FC(F)(F)c1cccnc1-n1cc(I)cn1 -US20070249670A1,2,COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1N)C1CCCCC1.O=C=Nc1c(Cl)cc(Cl)cc1Cl>>COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cc(Cl)cc1Cl)C1CCCCC1 -US06825201B2,7,CNC(=O)c1ccc(F)c2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12>>CNC(=O)c1ccc(F)c2c(C(O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 -US20140142122A1,1,Cc1cc(C)n2nc(S)nc2n1.Fc1cc(OCCBr)ccc1Cl>>Cc1cc(C)n2nc(SCCOc3ccc(Cl)c(F)c3)nc2n1 -US20090176823A1,2,CN.O=C(O)CCc1ccc(Cl)c(CO)c1>>CNC(=O)CCc1ccc(Cl)c(CO)c1 -US06248740B1,1,CCOC(=O)C(C)(C)c1cn2nc(Cl)ccc2n1.NCCCN1CCC(OC2c3ccccc3CCc3ccccc32)CC1>>CCOC(=O)C(C)(C)c1cn2nc(NCCCN3CCC(OC4c5ccccc5CCc5ccccc54)CC3)ccc2n1 -US05185360,4,CC1(C)CC(=O)c2ccccc21.NNc1ccccc1>>CC1(C)c2ccccc2-c2[nH]c3ccccc3c21 -US20150166480A1,6,COC(=O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCCC4)CC3)nc2)cc1>>O=C(O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCCC4)CC3)nc2)cc1 -US20020183307A1,7,CCCCC1(CCCC)CSc2ccc(F)cc2N(c2ccc(OC)cc2)C1=O>>CCCCC1(CCCC)CSc2ccc(F)cc2N(c2ccc(OC)cc2)C1 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.O=C(Cl)N1CCCCC1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)N4CCCCC4)nc3cc21 -US20130178488A1,1,N#Cc1cc(CO)ccc1Oc1cccc(C(F)(F)F)n1.O=c1nc(Cl)cc2n1CCc1cc(F)ccc1-2>>N#Cc1cc(COc2cc3n(c(=O)n2)CCc2cc(F)ccc2-3)ccc1Oc1cccc(C(F)(F)F)n1 -US20110118230A1,1,Nc1cnc(F)cc1-c1cc(Br)cnc1F>>Fc1cc2c(cn1)[nH]c1ncc(Br)cc12 -US20090036422A1,2,COc1ccc(Cl)cc1NCCc1ccc(C(F)(F)F)cc1.O=C(O)C(=O)c1ccccc1>>COc1ccc(Cl)cc1N(CCc1ccc(C(F)(F)F)cc1)C(=O)C(=O)c1ccccc1 -US07166629B2,2,C[Si](C)(C)CCOCn1nc(N)c2cc(-c3ccccc3)c(Cl)cc21.O=C=Nc1ccccc1>>C[Si](C)(C)CCOCn1nc(NC(=O)Nc2ccccc2)c2cc(-c3ccccc3)c(Cl)cc21 -US09108939B2,2,O=C(NCC1CC1)Nc1ccc(OC2CCNCC2)cc1.O=C(O)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1>>O=C(NCC1CC1)Nc1ccc(OC2CCN(C(=O)c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1 -US20040039027A1,2,CCOC(=O)Cl.Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2n1CO>>CCOC(=O)OCn1c(S(=O)Cc2nccc(OCC(F)(F)F)c2C)nc2ccccc21 -US08637501B2,6,Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)nc31)CCN(C(=O)OC(C)(C)C)CC2>>Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)nc31)CCNCC2 -US20050131014A1,1,Cn1cccc1CO.Oc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>Cn1cccc1COc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 -US20050250784A1,2,COC(=O)c1cnc(N2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)s1.NO>>O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)s1 -US07807667B2,1,BrCc1ccccc1.Sc1nnc(-c2ccc3c(c2)OCO3)o1>>c1ccc(CSc2nnc(-c3ccc4c(c3)OCO4)o2)cc1 -US04855322,6,CCC(CCCCC1CCC2CC(=O)CC12)OC>>CCC(O)CCCCC1CCC2CC(=O)CC12 -US08563570B2,1,O=C(O)c1ccccc1.O=C(OCc1ccccc1)N1CCC[C@]2(CCN([C@@H]3CC[C@@H](O)CC3)C2=O)C1>>O=C(O[C@@H]1CC[C@H](N2CC[C@]3(CCCN(C(=O)OCc4ccccc4)C3)C2=O)CC1)c1ccccc1 -US20080221220A1,10,C=CCCC[C@@H](O)c1ccc(-c2ccc(Cl)cc2Cl)cc1.O>>OCCCCC[C@@H](O)c1ccc(-c2ccc(Cl)cc2Cl)cc1 -US06211199B1,2,CCOCCn1c(NC2CCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.COc1ccc(NS(C)(=O)=O)cc1C(=O)O>>CCOCCn1c(NC2CCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(NS(C)(=O)=O)ccc4OC)C3)CC2)nc2ccccc21 -US06160126,2,CC(=O)OC(C)=O.CSC(=N[N+](=O)[O-])NCc1cnc(Cl)s1>>CSC(=N[N+](=O)[O-])N(Cc1cnc(Cl)s1)C(C)=O -US07491819B1,1,BrCc1ccccc1.CCOC(=O)c1nc2n(c(=O)c1O)CCOC2(C)C>>CCOC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CCOC2(C)C -US20120107275A1,9,Cc1cc(-c2cc(F)c(F)cn2)on1.NN>>Cc1cc(-c2cc(F)c(NN)cn2)on1 -US20100152192A1,2,COc1cccc(/C=C/c2nc3sccn3c2C(=O)O)c1OCC(C)(C)C.Nc1nc(C(F)(F)F)cs1>>COc1cccc(/C=C/c2nc3sccn3c2C(=O)Nc2nc(C(F)(F)F)cs2)c1OCC(C)(C)C -US20060183904A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOC(=O)CC#N>>CCOC(=O)C(C#N)=C1CCN(C(=O)OC(C)(C)C)CC1 -US06384051B1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Cc1cccc(O)c1N>>COc1cc2ncc(C#N)c(Nc3c(C)cccc3O)c2cc1OC -US20120142705A1,2,COc1ccc2c(c1)C(=O)C(=O)N2C(CC1CCCC1)C(=O)O.Cn1ccc(N)n1>>COc1ccc2c(c1)C(=O)C(=O)N2C(CC1CCCC1)C(=O)Nc1ccn(C)n1 -US05719291,8,CO[C@H]1[C@@H](C)CO[C@@H](CO)[C@@H]1O[Si](C)(C)C(C)(C)C>>CO[C@H]1[C@@H](C)CO[C@@H](C=O)[C@@H]1O[Si](C)(C)C(C)(C)C -US06380215B1,6,CCOC(=O)C1CCCN(C(=O)COC2CCN(C(=O)OCc3ccccc3)CC2)C1>>O=C(O)C1CCCN(C(=O)COC2CCN(C(=O)OCc3ccccc3)CC2)C1 -US04943652,7,CCOC(=O)C(=O)c1ccccc1>>CCOC(=O)[C@@H](O)c1ccccc1 -US20140200344A1,1,CC(=O)c1cnc2c(ccn2COCC[Si](C)(C)C)c1Cl.NC1CCN(Cc2ccccc2)CC1>>CC(=O)c1cnc2c(ccn2COCC[Si](C)(C)C)c1NC1CCN(Cc2ccccc2)CC1 -US20150175562A1,4,CC(C)(C)c1cc(C(Br)C(=O)CC2CCCCC2)cc(C(C)(C)C)c1.NC(N)=S>>CC(C)(C)c1cc(-c2sc(N)nc2CC2CCCCC2)cc(C(C)(C)C)c1 -US20150152108A1,7,CCOC(=O)C=C(N)CC(=O)OCC>>CCOC(=O)CC(N)CC(=O)OCC -US20070219370A1,2,CC(C)(C)C(=O)Cl.O=C(Nc1c(Cl)cccc1CO)c1cnc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)s1>>CC(C)(C)C(=O)OCc1cccc(Cl)c1NC(=O)c1cnc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)s1 -US20150133457A1,2,C=CC(=O)Cl.COc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1Oc1cccc(N)c1>>C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2OC)c1 -US20090227591A1,3,CC(C)(C)NC(=O)c1cc(I)cnn1.OB(O)C1=C(Br)CCC1>>CC(C)(C)NC(=O)c1cc(C2=C(Br)CCC2)cnn1 -US20120030841A1,3,C=C(Br)C(F)(F)F.OB(O)c1cc(Cl)cc(Cl)c1>>C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F -US20110166139A1,1,CNC(=O)c1cc(N2CCN(C)CC2)ccc1N.Clc1cc(I)c(Cl)cn1>>CNC(=O)c1cc(N2CCN(C)CC2)ccc1Nc1cc(Cl)ncc1Cl -US20040058907A1,2,NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1.O=C=Nc1cccc(Cl)c1>>O=C(NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1)Nc1cccc(Cl)c1 -US20140288046A1,1,CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn[nH]c2n1.O=C(CBr)c1ccccc1Cl>>CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nnn(CC(=O)c3ccccc3Cl)c2n1 -US20080287479A1,1,COC1CCC(C(=O)CCl)CC1.CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCNCC1>>COC1CCC(C(=O)CN2CCC(n3c(=O)[nH]c4cc(S(C)(=O)=O)ccc43)CC2)CC1 -US06316415B1,7,CC(=O)NC(C(=O)OC(C)(C)C)C(C(O)C[N+](=O)[O-])N1CCc2ccccc2C1=O>>CC(=O)NC(C(=O)OC(C)(C)C)C(C(O)CN)N1CCc2ccccc2C1=O -US20060205787A1,9,C[C@]1(N2C(=O)c3cccc(NC(=O)CCl)c3C2=O)CCC(=O)NC1=O.[N-]=[N+]=[N-]>>C[C@]1(N2C(=O)c3cccc(NC(=O)CN=[N+]=[N-])c3C2=O)CCC(=O)NC1=O -US05646171,6,CCCc1nc(CO)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCc1nc(CO)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US08735584B2,1,Nc1ccc(NC(=O)c2ccccc2)cc1.O=c1[nH]c2nccc(Cl)c2c2ccc(Cl)cc12>>O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4cc(Cl)ccc4c23)cc1)c1ccccc1 -US04960889,6,CCOC(=O)C(=NOC)c1noc(N)n1>>CON=C(C(=O)O)c1noc(N)n1 -US20080146616A1,1,CC(C)Oc1ccc(B(O)O)cc1.CCOC(=O)c1[nH]c2ccc(-c3ccc(C(C)(C)C)cc3)cc2c1-c1ccc(OC(C)C)cc1>>CCOC(=O)c1c(-c2ccc(OC(C)C)cc2)c2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1 -US05663173,2,CC1(C)OCC(CO)O1.CS(=O)(=O)Cl>>CC1(C)OCC(COS(C)(=O)=O)O1 -US20120149662A1,7,CC(C)(C)C(=O)OCn1ccc2c(-c3cnn([C@H](CC=O)C4CCCC4)c3)cnnc21>>CC(C)(C)C(=O)OCn1ccc2c(-c3cnn([C@H](CCO)C4CCCC4)c3)cnnc21 -US07115640B2,2,CN(C)CC(=O)Cl.CN1C(=C2SC(=Nc3cccc(N)c3)N(Cc3ccccc3)C2=O)Sc2ccccc21>>CN(C)CC(=O)Nc1cccc(N=C2SC(=C3Sc4ccccc4N3C)C(=O)N2Cc2ccccc2)c1 -US20140228361A1,1,C1CCC2CNCCC2C1.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCl>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCC2CCCCC2C1 -US20080176832A1,1,Cc1noc(-c2ccc(-n3cc4c(n3)CCNCC4)cc2)n1.O=C1CCCC1>>Cc1noc(-c2ccc(-n3cc4c(n3)CCN(C3CCCC3)CC4)cc2)n1 -US07473790B2,1,CC(C)Oc1ccc(CCC2(C3CCCC3)CC(O)=C(Cl)C(=O)O2)cc1Cl.CC(C)n1c(S)nc2cc(Cl)ccc21>>CC(C)Oc1ccc(CCC2(C3CCCC3)CC(O)=C(Sc3nc4cc(Cl)ccc4n3C(C)C)C(=O)O2)cc1Cl -US20120217482A1,1,CCCCCCCCCCCCc1ccsc1.C[Sn](C)(C)Cl>>CCCCCCCCCCCCc1csc([Sn](C)(C)C)c1 -US20060009443A1,2,CS(=O)(=O)Cl.OCCn1c(SCc2noc(-c3cc(Cl)ccc3F)n2)nnc1-c1cccs1>>CS(=O)(=O)OCCn1c(SCc2noc(-c3cc(Cl)ccc3F)n2)nnc1-c1cccs1 -US20100298328A1,1,COCCCO.COc1ccc(C=O)cc1O>>COCCCOc1cc(C=O)ccc1OC -US20030144280A1,4,NNc1ccc(S(N)(=O)=O)nc1.O=C(CC(=O)C(F)(F)F)c1ccc(-c2cscn2)c(F)c1>>NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3cscn3)c(F)c2)cn1 -US05516774,2,Nc1ccc(C(=O)N2CCc3cccn3-c3ccccc32)c(Cl)c1.O=C(Cl)c1ccc(Cl)cc1Cl>>O=C(Nc1ccc(C(=O)N2CCc3cccn3-c3ccccc32)c(Cl)c1)c1ccc(Cl)cc1Cl -US20150031685A1,1,CC(C)(C)[Si](C)(C)O[C@H]1CCN(C[C@@H](O)c2cc(F)cc(C#N)c2)C1.CN>>CN[C@H](CN1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1cc(F)cc(C#N)c1 -US20040063720A1,1,N#Cc1cnc(Cl)s1.Nc1cc(N2CCN(CCCN3CCOCC3)CC2)ncn1>>N#Cc1cnc(Nc2cc(N3CCN(CCCN4CCOCC4)CC3)ncn2)s1 -US20080275022A1,2,CN1CCCN(c2ccc([N+](=O)[O-])c(C(=O)O)c2)CC1.Cc1ccc([N+](=O)[O-])cc1N>>Cc1ccc([N+](=O)[O-])cc1NC(=O)c1cc(N2CCCN(C)CC2)ccc1[N+](=O)[O-] -US08618096B2,2,CC(C)(O)C[C@H](N)CO.O=C(Cl)N1CCOCC1>>CC(C)(O)C[C@@H](CO)NC(=O)N1CCOCC1 -US20150152047A1,2,CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1ccc(CN2CC[C@@H](N)C2)c(C(F)(F)F)c1.COC(=O)Cl>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1ccc(CN2CC[C@@H](NC(=O)OC)C2)c(C(F)(F)F)c1 -US20090286778A1,3,C#Cc1cccc(NC(=O)OC(C)(C)C)c1.C[Si](C)(C)CCOCn1c(=O)oc2c(I)cc([N+](=O)[O-])cc21>>CC(C)(C)OC(=O)Nc1cccc(C#Cc2cc([N+](=O)[O-])cc3c2oc(=O)n3COCC[Si](C)(C)C)c1 -US20050113346A1,6,C#CCNc1ccc(S(=O)(=O)N(C)CC(=O)OC(C)(C)C)cc1>>C#CCNc1ccc(S(=O)(=O)N(C)CC(=O)O)cc1 -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.CS(=O)c1ccc(O)cc1>>CS(=O)c1ccc(Oc2ncnc3c2cnn3C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US08293768B2,6,CCOC(=O)c1sc(N2CCN(Cc3ccc(OC(F)F)cc3)C2=O)nc1C>>Cc1nc(N2CCN(Cc3ccc(OC(F)F)cc3)C2=O)sc1C(=O)O -US06147078,10,CCOC(=O)Cn1c(C)cnc(Cl)c1=O.O=C1CCC(=O)N1Br>>CCOC(=O)Cn1c(CBr)cnc(Cl)c1=O -US20100331293A1,1,Cc1c(N2CCN(c3ccccc3)CC2)nc2cc(F)cc(F)c2c1Cl.Nc1cncc(N2CCOCC2)c1>>Cc1c(N2CCN(c3ccccc3)CC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1 -US20150274696A1,1,CNC(=O)c1cnc(Cl)cc1NC1CCCC1.Nc1ccc2c(c1)C(F)(F)C(=O)N2>>CNC(=O)c1cnc(Nc2ccc3c(c2)C(F)(F)C(=O)N3)cc1NC1CCCC1 -US20110152245A1,1,CC(C)(C)OC(=O)N1CCOC(c2ccc(Br)cc2)C1.NC(=O)c1ccc(C(F)(F)F)cn1>>CC(C)(C)OC(=O)N1CCOC(c2ccc(NC(=O)c3ccc(C(F)(F)F)cn3)cc2)C1 -US20090253687A1,4,Nc1ccccn1.O=C1COc2ccc(C3=C(c4ccc(F)cc4)C(=O)OC3=O)cc2N1>>O=C1COc2ccc(C3=C(c4ccc(F)cc4)C(=O)N(c4ccccn4)C3=O)cc2N1 -US20060223829A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)C1(Br)CCC1>>CCOC(=O)C1(N2CCN(C(=O)OC(C)(C)C)CC2)CCC1 -US06610694B1,1,CCOC(=O)C(C)(C)Br.O=c1[nH]nc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn12>>CCOC(=O)C(C)(C)n1nc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn2c1=O -US20060270673A1,4,N#Cc1cnc(-c2ccc(CNCc3ccc(-c4csnn4)cc3)cc2)c(-c2ccccc2)c1.[N-]=[N+]=[N-]>>c1ccc(-c2cc(-c3nnn[nH]3)cnc2-c2ccc(CNCc3ccc(-c4csnn4)cc3)cc2)cc1 -US20130172317A1,1,CCOC(=O)CCn1c(=O)nc(SCC)[nH]c1=O.Cc1ccc(CBr)cc1>>CCOC(=O)CCn1c(=O)nc(SCC)n(Cc2ccc(C)cc2)c1=O -US20140088076A1,1,COc1cccc(Br)n1.Cc1ccc(F)cc1-c1ccc2cc(N)ncc2c1>>COc1cccc(Nc2cc3ccc(-c4cc(F)ccc4C)cc3cn2)n1 -US20130316938A1,3,CC/C=C\CC/C=C/C=O.c1ccc(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CC/C=C\CC/C=C/C=CCc1ccccc1 -US20060025400A1,7,O=C1CCCc2c1ccc1c2CCN(C(=O)C(F)(F)F)C1>>O=C(N1CCc2c(ccc3c2CCC[C@@H]3O)C1)C(F)(F)F -US06133303,1,O=C1CCNc2cc(O)ccc21.OCCn1ccnc1>>O=C1CCNc2cc(OCCn3ccnc3)ccc21 -US05631280,7,Cc1cccc(NC(=O)c2cccc([N+](=O)[O-])c2)c1C>>Cc1cccc(NC(=O)c2cccc(N)c2)c1C -US05225316,1,C1=COCCC1.C=C(C)C(=O)O>>C=C(C)C(=O)OC1CCCCO1 -US20150045378A1,6,COC(=O)CC(c1ccc(OC)c(OCc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)n2)c1)C1CC1>>COc1ccc(F)c(-c2ccc(COc3cc(C(CC(=O)O)C4CC4)ccc3OC)nc2CC(C)(C)C)c1 -US08642788B2,2,COc1cccc2cc(C(=O)O)c(=O)oc12.Nc1cccc(-c2ccccc2S(=O)(=O)N2CCOCC2)c1>>COc1cccc2cc(C(=O)Nc3cccc(-c4ccccc4S(=O)(=O)N4CCOCC4)c3)c(=O)oc12 -US20070149577A1,3,COc1ccc(F)cc1B(O)O.O=Cc1ccc(I)c(OCc2ccccc2)c1>>COc1ccc(F)cc1-c1ccc(C=O)cc1OCc1ccccc1 -US20100160369A1,6,COC(=O)Cc1ccc(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)c(Cl)c1>>O=C(O)Cc1ccc(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)c(Cl)c1 -US07005444B2,1,Nc1cc(-c2ccco2)[nH]n1.O=C1Nc2ccc(Cl)cc2/C1=C/O>>O=C1Nc2ccc(Cl)cc2C1=CNc1cc(-c2ccco2)[nH]n1 -US08952058B2,1,Brc1nc2ccc(Cn3cnc4ccccc43)cc2s1.N[C@@H]1CCCC[C@H]1O>>O[C@@H]1CCCC[C@H]1Nc1nc2ccc(Cn3cnc4ccccc43)cc2s1 -US20100179118A1,7,O=C(O)c1ccc(C(=O)C(F)(F)F)cc1>>O=C(O)c1ccc(C(O)C(F)(F)F)cc1 -US06245796B1,3,CC[Mg+].O=CCn1ncc2ccc3occc3c21>>CCC(O)Cn1ncc2ccc3occc3c21 -US04151288,2,Cc1ncoc1CSCCN.O=C(N=C=S)c1ccccc1>>Cc1ncoc1CSCCNC(=S)NC(=O)c1ccccc1 -US20070027173A1,1,ClCC1CN(Cc2ccccc2)CCO1.O=C(c1c[nH]c2cc(Cl)ccc12)N1CCC2(CC1)OCc1ccccc12>>O=C(c1cn(CC2CN(Cc3ccccc3)CCO2)c2cc(Cl)ccc12)N1CCC2(CC1)OCc1ccccc12 -US08236963B2,1,BrCc1ccccc1.CC(C)(C)OC(=O)CN1C(=O)C2(CNC(=O)C2)c2cc(Cl)ccc21>>CC(C)(C)OC(=O)CN1C(=O)C2(CC(=O)N(Cc3ccccc3)C2)c2cc(Cl)ccc21 -US20040209866A1,2,CNOC.Cc1cc2c(c(C(=O)O)n1)c(=O)cc(Nc1ccccc1)n2-c1ccccc1>>CON(C)C(=O)c1nc(C)cc2c1c(=O)cc(Nc1ccccc1)n2-c1ccccc1 -US08158656B2,1,NCCN.Nc1ccccc1NC(=O)c1ccc(Cl)nc1>>NCCNc1ccc(C(=O)Nc2ccccc2N)cn1 -US20060199817A1,1,Clc1ccc2c(Cl)nncc2c1.O=C1OC[C@@H]2CNCCN12>>O=C1OC[C@@H]2CN(c3nncc4cc(Cl)ccc34)CCN12 -US07935703B2,2,Clc1ccc(N2CCCNCC2)c(Cl)c1.O=C(Cl)COCc1ccccc1>>O=C(COCc1ccccc1)N1CCCN(c2ccc(Cl)cc2Cl)CC1 -US20130143858A1,2,CN[C@@H](C)CN1CC(O)C1.O=C(O)c1ccc(Br)cc1>>C[C@@H](CN1CC(O)C1)N(C)C(=O)c1ccc(Br)cc1 -US20120289500A1,2,Nn1nc(N2CCOCC2)c2ccccc2c1=O.O=C(O)Cc1cccc(Oc2ccccc2)c1>>O=C(Cc1cccc(Oc2ccccc2)c1)Nn1nc(N2CCOCC2)c2ccccc2c1=O -US20070270476A1,4,NC(=O)c1cccc(N)c1N.O=C(O)c1ccc(C2OCCCO2)cc1F>>NC(=O)c1cccc2[nH]c(-c3ccc(C4OCCCO4)cc3F)nc12 -US20080312234A1,2,CCCNc1nc(C(F)(F)F)ccc1C=CC(=O)O.C[C@@H](N)c1cc(F)c(NS(C)(=O)=O)c(F)c1>>CCCNc1nc(C(F)(F)F)ccc1C=CC(=O)N[C@H](C)c1cc(F)c(NS(C)(=O)=O)c(F)c1 -US05079264,1,CC(=O)c1ccc(F)cc1Cl.CN>>CNc1cc(F)ccc1C(C)=O -US07214824B2,7,CS(=O)(=O)Nc1c(F)cc(C#N)cc1F>>CS(=O)(=O)Nc1c(F)cc(CN)cc1F -US08497269B2,1,Nc1ccc(F)cc1.Oc1nncc2cc(Br)ccc12>>Oc1nncc2cc(Nc3ccc(F)cc3)ccc12 -US06730418B2,3,Cc1ccc2nc(C)cc(Cl)c2c1.FC(F)(F)c1cc([Mg+])cc(C(F)(F)F)c1>>Cc1ccc2nc(C)cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2c1 -US20100094000A1,4,CC(=O)CC(=O)c1ccc(F)cc1.NNCc1ccccn1>>Cc1cc(-c2ccc(F)cc2)n(Cc2ccccn2)n1 -US20090054508A1,6,CCOC(=O)c1cnc(Nc2ccccc2/C=C/c2n[nH]c3ccccc23)s1>>O=C(O)c1cnc(Nc2ccccc2/C=C/c2n[nH]c3ccccc23)s1 -US07569601B2,3,O=C(c1cccc(O)c1)c1ccc(Br)c(F)c1.O=C1CCCCCC1>>Oc1cccc(C(=C2CCCCCC2)c2ccc(Br)c(F)c2)c1 -US06313310B1,7,COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CC(O)c3cccc([N+](=O)[O-])c3)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CC(O)c3cccc(N)c3)c21 -US20060058528A1,1,CCOC(=O)C(=CNCCF)C(=O)c1cc(F)c(F)c(F)c1F>>CCOC(=O)c1cn(CCF)c2c(F)c(F)c(F)cc2c1=O -US20150152058A1,2,COC(=O)CNc1cnccc1-c1cc(F)c(F)cc1OC.CS(=O)(=O)c1cc(C(=O)O)cc(C(F)(F)F)c1>>COC(=O)CN(C(=O)c1cc(C(F)(F)F)cc(S(C)(=O)=O)c1)c1cnccc1-c1cc(F)c(F)cc1OC -US20070082912A1,7,COC(=O)c1cc(N2CCCC2=O)cc([N+](=O)[O-])c1>>COC(=O)c1cc(N)cc(N2CCCC2=O)c1 -US20110034500A1,9,CCCCCN1C(=O)C(O)(c2cc3c(cc2O)OCO3)c2cnccc21>>CCCCCN1C(=O)C(c2cc3c(cc2O)OCO3)c2cnccc21 -US20130079328A1,6,CC(C)(C)OC(=O)c1ccc(-c2cccc(F)c2)cn1>>O=C(O)c1ccc(-c2cccc(F)c2)cn1 -US20040242884A1,1,CNCC(O)c1cccc(NC(C)=O)c1.Cc1c(CCl)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12>>CC(=O)Nc1cccc(C(O)CN(C)Cc2sc3c(=O)c(C(=O)NCc4ccc(Cl)cc4)cn(C)c3c2C)c1 -US20100063091A1,3,COC(=O)c1cc(C=O)cc(OCc2ccccc2)c1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>COC=Cc1cc(OCc2ccccc2)cc(C(=O)OC)c1 -US20030130340A1,1,COc1cccc(B(O)O)c1.Oc1ccc2c(-c3cccnc3)csc2c1>>COc1cccc(Oc2ccc3c(-c4cccnc4)csc3c2)c1 -US20070225292A1,6,COCc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCCCN2C(=O)OC(C)(C)C)c2ccccc12>>COCc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCCCN2)c2ccccc12 -US20140024650A1,1,CCS(=O)(=O)NC1CCC2(CC1CO)OCCO2.Oc1ccc(-n2cccn2)cc1>>CCS(=O)(=O)N[C@@H]1CCC2(C[C@H]1COc1ccc(-n3cccn3)cc1)OCCO2 -US20150087663A1,1,CC(C)C(N)=NOC(=O)c1c(N)ncnc1Cl>>CC(C)c1noc(-c2c(N)ncnc2Cl)n1 -US20150028323A1,1,CC(C)c1cccc(C(C)C)c1-c1cnc2c3cc(O)ccc3c3ccccc3n12.Cc1ccnc(-n2c3ccccc3c3ccc(Br)cc32)c1>>Cc1ccnc(-n2c3ccccc3c3ccc(Oc4ccc5c6ccccc6n6c(-c7c(C(C)C)cccc7C(C)C)cnc6c5c4)cc32)c1 -US08173650B2,6,CC(C)(C)OC(=O)N1CC(N2CC[C@H](O)C2)C1>>O[C@H]1CCN(C2CNC2)C1 -US20090176825A1,1,COC(=O)c1ccsc1N.O=Cc1ccccc1>>COC(=O)c1ccsc1NCc1ccccc1 -US20130165472A1,3,C=Cn1c(-c2cc(NC(C)=O)ncc2Br)nc(-c2ccc(Cl)cc2Cl)c1C(=O)OC>>COC(=O)c1c(-c2ccc(Cl)cc2Cl)nc2c3cc(NC(C)=O)ncc3ccn12 -US20130040951A9,1,CCN1C(=N)/C(=C/c2ccc(O)c(OC)c2)NC1=O.N#Cc1ccc(F)c2ccccc12>>CCN1C(=N)/C(=C/c2ccc(Oc3ccc(C#N)c4ccccc34)c(OC)c2)NC1=O -US07790717B2,7,O=CCOCc1ccc(-c2ccc(CN3CC4(CCCCC4)OC3=O)cc2)cc1>>O=C1OC2(CCCCC2)CN1Cc1ccc(-c2ccc(COCCO)cc2)cc1 -US20050148627A1,9,CC(C)(O)c1cc(OC(F)(F)F)cc2c1OC(C(F)(F)F)C(C(=O)O)=C2>>CC(C)c1cc(OC(F)(F)F)cc2c1OC(C(F)(F)F)C(C(=O)O)=C2 -US05310951,1,CCCc1c(OCCCI)ccc2c1OC(CCC(=O)OCC)CC2.CNC(=O)c1ccc(O)c(CC2CC2)c1O>>CCCc1c(OCCCOc2ccc(C(=O)NC)c(O)c2CC2CC2)ccc2c1OC(CCC(=O)OCC)CC2 -US20070105855A1,6,CCOC(=O)CNc1ccc2oc3c(OC)ccc(C(=O)Nc4c(Cl)cncc4Cl)c3c2c1>>COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c1oc1ccc(NCC(=O)O)cc12 -US04342870,1,Cc1nc2ccccn2c(=O)c1CCCl.O=C(c1ccc(F)cc1)C1CCNCC1>>Cc1nc2ccccn2c(=O)c1CCN1CCC(C(=O)c2ccc(F)cc2)CC1 -US07750155B2,6,CC(C)(C)OC(=O)N[C@@H]1CCN(CC23CCC(CC2)O3)C1>>N[C@@H]1CCN(CC23CCC(CC2)O3)C1 -US20080167378A1,7,CC(C)Oc1ccc(C=O)cc1>>CC(C)Oc1ccc(CO)cc1 -US05021435,1,CCCCCCCCCC1SC(c2cccnc2)N(CCCl)C1=O.CNC>>CCCCCCCCCC1SC(c2cccnc2)N(CCN(C)C)C1=O -US20080146569A1,3,CC(C)(C)OC(=O)c1ccc(Br)nc1.OB(O)c1cc(F)ccc1F>>CC(C)(C)OC(=O)c1ccc(-c2cc(F)ccc2F)nc1 -US20140249126A1,2,COc1ccc(COc2cn(C)c3ccc(C(=O)O)cc3c2=O)cc1.NCCN1CCCC1>>COc1ccc(COc2cn(C)c3ccc(C(=O)NCCN4CCCC4)cc3c2=O)cc1 -US20120101082A1,1,CC(C)C=O.Cn1ncc2c1Nc1ccccc1N(C(=O)C1CCC(CNC(=O)C3CCNCC3)CC1)C2>>CC(C)CN1CCC(C(=O)NCC2CCC(C(=O)N3Cc4cnn(C)c4Nc4ccccc43)CC2)CC1 -US20130184255A1,3,O=C1CCOc2ccc(-c3ccc(OC(F)(F)F)cc3)cc21.O=Cc1ccccn1>>O=C1C(=Cc2ccccn2)COc2ccc(-c3ccc(OC(F)(F)F)cc3)cc21 -US20080319080A1,2,C#CCOc1ccc(C(=O)Cl)cc1F.CC(C)C(C)(N)C#N>>C#CCOc1ccc(C(=O)NC(C)(C#N)C(C)C)cc1F -US20070244125A1,2,C1CSCCN1.O=C(O)c1cc2cc(C(=O)N3CCN(C4CCCC4)CC3)ccc2[nH]1>>O=C(c1ccc2[nH]c(C(=O)N3CCSCC3)cc2c1)N1CCN(C2CCCC2)CC1 -US04729847,1,CCCCCCC(C)Oc1ccc(O)cc1.O=C(O)c1ccc(OCc2ccccc2)cc1>>CCCCCCC(C)Oc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1 -US07160877B2,1,N[C@H]1CC[C@H](O)CC1.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(N[C@@H]2CC[C@@H](O)CC2)nc1 -US20130330272A1,1,C1CCNCC1.CC1CC(=O)CC(C)(C)C1>>CC1CC(N2CCCCC2)CC(C)(C)C1 -US20120114544A1,9,Cl[Si](Cl)(Cl)c1ccc([Si](Cl)(Cl)Cl)cc1>>Cl[SiH](Cl)c1ccc([Si](Cl)(Cl)Cl)cc1 -US20040110767A1,1,Nc1ccc(I)cc1.O=Cc1cccc(OC2CCCCO2)c1>>Ic1ccc(NCc2cccc(OC3CCCCO3)c2)cc1 -US20060111362A1,1,CC(C)(C)OC(=O)N1CCN(c2ncnc3[nH]cnc23)CC1.CI>>Cn1cnc2c(N3CCN(C(=O)OC(C)(C)C)CC3)ncnc21 -US20110275611A1,2,CC[C@@H]1CO[C@H](C(=O)O)CN1C(=O)OC(C)(C)C.Nc1ccccc1>>CC[C@@H]1CO[C@H](C(=O)Nc2ccccc2)CN1C(=O)OC(C)(C)C -US20100331312A1,7,COc1cc(CC#N)ccc1C>>COc1cc(CCN)ccc1C -US05342610,1,ClCC1CO1.O=C(c1ccccc1)c1ccc(O)cc1>>O=C(c1ccccc1)c1ccc(OCC2CO2)cc1 -US20030232869A1,6,COCOCC(=O)c1cc2c(ncn2C)c(F)c1Nc1ccc(Br)cc1Cl>>Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(C(=O)CO)cc21 -US07560731B2,1,C1=COCCC1.OCCCCCCBr>>BrCCCCCCOC1CCCCO1 -US07696213B2,2,CCOC(=O)/C=C/c1c(C)nc(N)nc1N[C@@H]1CC[C@H](OCCO)CC1>>Cc1nc(N)nc2c1ccc(=O)n2[C@@H]1CC[C@H](OCCO)CC1 -US20150141400A1,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.CCOC(=O)c1cc(Cl)c(CBr)cc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CCOC(=O)c1cc(Cl)c(CN2CC[C@@H](NC(=O)OC(C)(C)C)C2)cc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US07229987B2,6,COC(=O)c1ccc(-c2nnc(CCCc3ccccc3)o2)cc1>>O=C(O)c1ccc(-c2nnc(CCCc3ccccc3)o2)cc1 -US06867204B2,2,Cc1cc(Br)c2c(c1)NCCO2.O=C(Cl)OCc1ccccc1>>Cc1cc(Br)c2c(c1)N(C(=O)OCc1ccccc1)CCO2 -US20150005258A1,6,CN(CC(=O)NCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C>>CNCC(=O)NCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 -US08354399B2,5,CCOC(=O)N1CCC(Nc2cc(N3CCN(C)CC3)ccc2C(=O)OC(C)(C)C)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)N1CCC(N(C(=O)C(F)(F)F)c2cc(N3CCN(C)CC3)ccc2C(=O)OC(C)(C)C)CC1 -US07560463B2,1,CCCCCC=O.NC(=O)c1ccc(Oc2ccc(C3CCCNC3)cc2)nc1>>CCCCCCN1CCCC(c2ccc(Oc3ccc(C(N)=O)cn3)cc2)C1 -US20090264416A1,6,CC1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1ccc(NC(=O)NC2CCC2)cc1>>C[C@H]1CNCCN1C(=O)c1ccc(NC(=O)NC2CCC2)cc1 -US06943253B2,1,CCC=O.CCCOc1ccc(S(=O)(=O)N2CCNCC2)cc1-c1cc2c(=O)n(C)c(=O)n(CCC)c2[nH]1>>CCCOc1ccc(S(=O)(=O)N2CCN(CCC)CC2)cc1-c1cc2c(=O)n(C)c(=O)n(CCC)c2[nH]1 -US05073558,2,CCOCCc1ccc(OCCN(C(=O)Cl)c2ncnc(C)c2Cl)c(C)c1.CN>>CCOCCc1ccc(OCCN(C(=O)NC)c2ncnc(C)c2Cl)c(C)c1 -US20150239837A1,2,COC(=O)c1ccc2c(c1)c(C(C)=O)cn2CC(=O)O.O=C(NCc1cccc(Cl)c1F)[C@@H]1C[C@@H](F)CN1>>COC(=O)c1ccc2c(c1)c(C(C)=O)cn2CC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F -US05585377,7,CC(C)(C)NS(=O)(=O)c1cc2c(s1)S(=O)(=O)NCC2=O>>CC(C)(C)NS(=O)(=O)c1cc2c(s1)S(=O)(=O)NC[C@H]2O -US06706725B1,7,CC/C(=C\C#CC(O)(C(F)(F)F)C(F)(F)F)c1ccc(COc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)s1>>CC/C(=C\C=C\C(O)(C(F)(F)F)C(F)(F)F)c1ccc(COc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)s1 -US06960578B2,3,C#Cc1ccc(C)cc1.CC(C)(C)OC(=O)Nc1ccc(I)cc1[N+](=O)[O-]>>Cc1ccc(C#Cc2ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c2)cc1 -US04267179,1,COc1ccc(N2CCNCC2)cc1.O=[N+]([O-])c1ccc(Cl)cc1>>COc1ccc(N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc1 -US20150094297A1,6,CC(C)(C)[Si](C)(C)OCc1csc(C2(O)CCC(F)(F)CC2)n1>>OCc1csc(C2(O)CCC(F)(F)CC2)n1 -US20150225412A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]1CN.O=[N+]([O-])c1ccccc1F>>CC(C)(C)OC(=O)N1CCC[C@@H]1CNc1ccccc1[N+](=O)[O-] -US06211184B1,6,CCOC(=O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C[C@H]1C>>C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CC(=O)O -US20090233937A1,2,CC(C)(CO)C(=O)O.NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21>>CC(C)(CO)C(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21 -US07960419B2,3,C[C@@H]1C[C@H]1C(=O)Nc1snc(Br)c1Br.OB(O)c1ccc(F)cc1>>C[C@@H]1C[C@H]1C(=O)Nc1snc(-c2ccc(F)cc2)c1Br -US08269043B2,2,CNOC.O=C(O)[C@@H]1CC[C@H](O)CC1>>CON(C)C(=O)[C@@H]1CC[C@H](O)CC1 -US20150018342A1,7,CCOC(=O)C1C(C)OCC(=O)N1Cc1ccccc1>>CCOC(=O)C1C(C)OCCN1Cc1ccccc1 -US20100197687A1,7,CCOC(=O)C=Cc1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC2CCCC2)cc1>>CCOC(=O)CCc1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC2CCCC2)cc1 -US04578393,6,COc1ccc2c(c1)CC(N(C)C)=NC2c1ccc(Cl)cc1>>CN(C)C1=NC(c2ccc(Cl)cc2)c2ccc(O)cc2C1 -US08598168B2,1,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(Cl)nc1.CN1CCNCC1>>CN1CCN(c2ccc(C(=O)Nc3cc(-c4cccs4)ccc3NC(=O)OC(C)(C)C)cn2)CC1 -US20090048285A1,1,Cc1cc(Cl)ncc1[N+](=O)[O-].Oc1cccc(C(F)(F)F)c1>>Cc1cc(Oc2cccc(C(F)(F)F)c2)ncc1[N+](=O)[O-] -US06541668B1,1,CN(C)CCC(O)c1ccccc1.Cc1ccccc1F>>Cc1ccccc1OC(CCN(C)C)c1ccccc1 -US03960967,1,CC(=O)OCC=C(C)CCl.O=S([O-])c1ccccc1>>CC(=O)OCC=C(C)CS(=O)(=O)c1ccccc1 -US20130296312A1,7,CN(c1ncccc1[N+](=O)[O-])S(C)(=O)=O>>CN(c1ncccc1N)S(C)(=O)=O -US20100029701A1,7,COC(=O)CCCN1C(=O)N=C(NC2CCCCC2)C12CCN(Cc1ccc(C#N)cc1)CC2>>COC(=O)CCCN1C(=O)N=C(NC2CCCCC2)C12CCN(Cc1ccc(CN)cc1)CC2 -US20080221178A1,1,CC(C)c1nc2cc(NS(=O)(=O)c3ccccc3)ccc2n1CC1CCCCC1.CI>>CC(C)c1nc2cc(N(C)S(=O)(=O)c3ccccc3)ccc2n1CC1CCCCC1 -US20100029606A1,1,BrCC1CC1.COC(=O)c1ccc(O)c(OC)c1>>COC(=O)c1ccc(OCC2CC2)c(OC)c1 -US06680312B2,2,CC(C)(C)OC(=O)N1CCC(CN2CCNCC2=O)CC1.O=S(=O)(Cl)CCl>>CC(C)(C)OC(=O)N1CCC(CN2CCN(S(=O)(=O)CCl)CC2=O)CC1 -US20100160308A1,1,COC(OC)c1ccc([N+](=O)[O-])c(F)c1.NC(=O)c1sc(N)nc1-c1ccc(Cl)cc1>>COC(OC)c1ccc([N+](=O)[O-])c(Nc2nc(-c3ccc(Cl)cc3)c(C(N)=O)s2)c1 -US09073922B2,3,Clc1ccc(I)nc1Br.OB(O)c1ccccc1>>Clc1ccc(-c2ccccc2)nc1Br -US20110110889A1,1,C=O.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3c(c2)cc(C2=CCNCC2)n3S(=O)(=O)c2ccccc2)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3c(c2)cc(C2=CCN(C)CC2)n3S(=O)(=O)c2ccccc2)c1F -US07531568B2,1,COC(=O)CBr.COc1ccc(S(=O)(=O)n2cc(O)c3cc(Br)ccc32)cc1>>COC(=O)COc1cn(S(=O)(=O)c2ccc(OC)cc2)c2ccc(Br)cc12 -US20090291942A1,7,CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CO)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(CCCO)cc1 -US20100317697A1,6,COCCCCC(O)(c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)C[C@@H](CC2CCCCC2)CN(C)C(=O)OC(C)(C)C)C1>>CNC[C@@H](CC(=O)N1CCC[C@@H](C(O)(CCCCOC)c2cccc(Cl)c2)C1)CC1CCCCC1 -US05424316,1,C=CCBr.CCCc1nc2c(n1Cc1ccc(-c3ccccc3C(=O)OC(C)(C)C)cc1)C(C(=O)OCC)NCC2>>C=CCN1CCc2nc(CCC)n(Cc3ccc(-c4ccccc4C(=O)OC(C)(C)C)cc3)c2C1C(=O)OCC -US09130244B2,2,C#CCO.CC(O)C(=O)O>>C#CCOC(=O)C(C)O -US20120208827A1,1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.O=[N+]([O-])c1ccc(C(F)(F)F)cc1Cl>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2cc(C(F)(F)F)ccc2[N+](=O)[O-])C1 -US20070232607A1,2,CNCCCO.Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@H](C)C(=O)O)c34)cc2C)cn1>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@H](C)C(=O)N(C)CCCO)c34)cc2C)cn1 -US20090163520A1,2,Cn1ccnc1C(=O)O.Nc1cccc(-n2ncc3c(N)ncnc32)c1>>Cn1ccnc1C(=O)Nc1cccc(-n2ncc3c(N)ncnc32)c1 -US06867218B2,7,CCOC(=O)/C=C(\C)c1ccc(I)cc1>>C/C(=C\CO)c1ccc(I)cc1 -US06548126B1,1,CCC[C@@H]1CC[C@@H](c2ccc(O)c(F)c2F)CC1.CCOc1ccc(C(=O)O)c(F)c1F>>CCC[C@@H]1CC[C@@H](c2ccc(OC(=O)c3ccc(OCC)c(F)c3F)c(F)c2F)CC1 -US20150126490A1,1,CCBr.COC(=O)c1ccc(-c2nc(-c3cn[nH]c3)cnc2N)cc1F>>CCn1cc(-c2cnc(N)c(-c3ccc(C(=O)OC)c(F)c3)n2)cn1 -US20140155648A1,2,CC(=O)O[C@@H](C)C(=O)Cl.Nc1c(I)c(C(=O)O)c(I)c(C(=O)O)c1I>>CC(=O)O[C@@H](C)C(=O)Nc1c(I)c(C(=O)O)c(I)c(C(=O)O)c1I -US05397798,2,NCCCn1cccn1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NCCCn1cccn1 -US20070265270A1,7,COc1ccc(C2OCC(=O)NC2C)cc1>>COc1ccc(C2OCCNC2C)cc1 -US20110263571A1,1,CC[C@@H]1COC(=O)N1.O=C(c1ccc(I)cc1)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1>>CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C4CC4)cc3C3CC3)CC2)cc1 -US04576940,6,CC(=O)Oc1ccc2c(c1)c(C(=O)NC1CCN(CCc3ccccc3)CC1)c(C)n2Cc1ccccc1>>Cc1c(C(=O)NC2CCN(CCc3ccccc3)CC2)c2cc(O)ccc2n1Cc1ccccc1 -US20080318925A1,3,COc1ccc(OC)c(B(O)O)c1.Nc1c(C(=O)NC2CC2)nnc2c(Br)cccc12>>COc1ccc(OC)c(-c2cccc3c(N)c(C(=O)NC4CC4)nnc23)c1 -US20080119488A1,1,CCOC(=O)c1cc2ccc(O)cc2[nH]1.Cc1ccc(Cn2c(-c3cccc(Br)c3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1>>CCOC(=O)c1cc2ccc(Oc3cccc(-c4cc(C(F)(F)F)c(C#N)c(=O)n4Cc4ccc(C)cc4C)c3)cc2[nH]1 -US07183295B2,9,O=C(CCCCl)c1ccccc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCCC(=O)c1ccccc1 -US04472380,1,CC(C)CC(=O)C(=O)O.C[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O>>CC(C)CC(N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)C(=O)O -US20080188484A1,6,CCOC(=O)c1cc2cc(OC)c(Br)cc2[nH]1>>CCOC(=O)c1cc2cc(O)c(Br)cc2[nH]1 -US20140200197A1,2,COC(=O)N[C@H](C(=O)Nc1ccccc1CC[C@@H]1CN(C(=O)OC(C)(C)C)[C@H](C(=O)O)CO1)C(c1ccccc1)c1ccccc1.NCc1ccccc1>>COC(=O)N[C@H](C(=O)Nc1ccccc1CC[C@@H]1CN(C(=O)OC(C)(C)C)[C@H](C(=O)NCc2ccccc2)CO1)C(c1ccccc1)c1ccccc1 -US20150203505A1,9,CNC(=O)c1[nH]c2c(Br)cc3c(c2c1CCNC(=O)OC(C)(C)C)CCO3>>CNC(=O)c1[nH]c2ccc3c(c2c1CCNC(=O)OC(C)(C)C)CCO3 -US06005116,6,COc1ccc(-c2cc(O)no2)cc1>>Oc1ccc(-c2cc(O)no2)cc1 -US20110124619A1,1,COc1cc(NS(=O)(=O)N2CCC2)nc(SCc2cccc(F)c2F)n1.COc1ccc(CCl)cc1>>COc1ccc(CN(c2cc(OC)nc(SCc3cccc(F)c3F)n2)S(=O)(=O)N2CCC2)cc1 -US04911753,2,O=C(O)c1cc2cc(OC(F)F)ccc2nc1C(=O)O>>O=C1OC(=O)c2nc3ccc(OC(F)F)cc3cc21 -US07326791B2,2,Cc1cc(C(=O)O)ccc1C(=O)N1CCCC1.NC(CCC(=O)OCc1ccccc1)c1nc2cc(Cl)ccc2[nH]1>>Cc1cc(C(=O)NC(CCC(=O)OCc2ccccc2)c2nc3cc(Cl)ccc3[nH]2)ccc1C(=O)N1CCCC1 -US20070254940A1,7,O=[N+]([O-])c1ccc2c(ccn2-c2cccnc2)c1>>Nc1ccc2c(ccn2-c2cccnc2)c1 -US20080318923A1,1,CN(C)C(=O)C1(N)CCCCC1.COc1ccccc1C1(Cl)C(=O)Nc2ccc(Cl)cc21>>COc1ccccc1C1(NC2(C(=O)N(C)C)CCCCC2)C(=O)Nc2ccc(Cl)cc21 -US08592467B2,1,O=c1cccn[nH]1.O[C@H]1C[C@@H](c2nc3ccc(Br)cc3s2)C1>>O=c1cccnn1-c1ccc2nc(C3CC(O)C3)sc2c1 -US05401868,1,CC(=O)C(=O)O.CCSC(=O)OCI>>CCSC(=O)OCOC(=O)C(C)=O -US20070032502A1,1,CN(C)CCCO.Clc1nc(CN2CCN(Cc3ccccc3)CC2)nc2ccccc12>>CN(C)CCCOc1nc(CN2CCN(Cc3ccccc3)CC2)nc2ccccc12 -US20060229312A1,2,Cc1ccc2c(N3CCN(CCc4cccc(N)c4)CC3)cccc2n1.O=C1NCC(C(=O)O)N1>>Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)C5CNC(=O)N5)c4)CC3)cccc2n1 -US20090286778A1,2,O=C(CC1CNC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2.O=C(O)c1cn[nH]c1>>O=C(CC1CN(C(=O)c2cn[nH]c2)C1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2 -US20120316200A1,1,CC(C)(CO)CBr.O=c1cc(OCc2ccc(F)cc2)ccn1-c1ccc(O)cc1>>CC(C)(CO)COc1ccc(-n2ccc(OCc3ccc(F)cc3)cc2=O)cc1 -US08703805B2,2,CC(=O)Cl.CC(C)(O)c1cc(-c2ccc(-c3cccc(N)c3)cc2)n(-c2ccccc2Cl)n1>>CC(=O)Nc1cccc(-c2ccc(-c3cc(C(C)(C)O)nn3-c3ccccc3Cl)cc2)c1 -US08324262B2,2,C1COCCN1.CCOC(=O)CCCOc1ccc2c(c1)C(=O)CCC2>>O=C1CCCc2ccc(OCCCC(=O)N3CCOCC3)cc21 -US20140364412A1,2,CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2N)cc1CO)(C(C)C)C(C)C.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1CO)(C(C)C)C(C)C -US20140057896A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cc(F)cc1N1CCn2c(cc3c2CCCC3)C1=O.Cn1cc(Br)nc(Nc2ccc(N3CCN(C4COC4)CC3)cc2)c1=O>>CC(=O)OCc1c(-c2cn(C)c(=O)c(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)cc(F)cc1N1CCn2c(cc3c2CCCC3)C1=O -US04066457,7,O=[N+]([O-])c1ccc(N2CCCC2)c(S(=O)(=O)O)c1>>Nc1ccc(N2CCCC2)c(S(=O)(=O)O)c1 -US20100227902A1,2,COc1ccc(S(=O)(=O)Cl)cc1.Nc1cc(Br)ccc1C(=O)c1ccccc1>>COc1ccc(S(=O)(=O)Nc2cc(Br)ccc2C(=O)c2ccccc2)cc1 -US20090264420A1,2,CS(=O)(=O)Cl.OCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CS(=O)(=O)OCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US20130005707A1,1,Clc1cc(I)ccn1.Nc1nc2cccc(-c3ccccc3)n2n1>>Clc1cc(Nc2nc3cccc(-c4ccccc4)n3n2)ccn1 -US20130158038A1,2,CCNCC(=O)c1ccc(F)c(C)c1.O=C(Cl)COCc1ccccc1>>CCN(CC(=O)c1ccc(F)c(C)c1)C(=O)COCc1ccccc1 -US20080318963A1,2,CCOC(=O)Nc1nc2ccc(OC)cc2nc1OC.Fc1ccc(N2CCNCC2)cc1>>COc1ccc2nc(NC(=O)N3CCN(c4ccc(F)cc4)CC3)c(OC)nc2c1 -US20090227570A1,2,CN1CCN(CC(=O)O)CC1.COc1cccc2c1C(Nc1ccc3cc(N)ccc3n1)CO2>>COc1cccc2c1C(Nc1ccc3cc(NC(=O)CN4CCN(C)CC4)ccc3n1)CO2 -US20060199817A1,3,Brc1ccc2c(N3CCOCC3)nncc2c1.COc1ccc(C(F)(F)F)cc1NC(=O)c1ccc(C)c(I)c1>>COc1ccc(C(F)(F)F)cc1NC(=O)c1ccc(C)c(-c2ccc3c(N4CCOCC4)nncc3c2)c1 -US05420273,8,CC(O)c1ccc2c(c1)SCCCC2>>CC(=O)c1ccc2c(c1)SCCCC2 -US20130137865A1,7,Cn1ncc(I)c1C=O>>Cn1ncc(I)c1CO -US07902367B2,1,COC(=O)c1ccccc1I.Cc1nc(-c2ccc(Cl)cc2)sc1CC(=O)NC1CCCNC1>>COC(=O)c1ccccc1N1CCCC(NC(=O)Cc2sc(-c3ccc(Cl)cc3)nc2C)C1 -US20070155744A1,6,O=c1c(OCc2ccccc2)cccn1Cc1ccccc1>>O=c1c(O)cccn1Cc1ccccc1 -US07977349B2,6,CCOC(=O)C[C@H]1CCCN(c2c(F)cc3c(=O)c(C(=O)NCc4ccc(OC(F)(F)F)cc4C)cn(CC(F)(F)F)c3c2OC)C1>>COc1c(N2CCC[C@H](CC(=O)O)C2)c(F)cc2c(=O)c(C(=O)NCc3ccc(OC(F)(F)F)cc3C)cn(CC(F)(F)F)c12 -US08546376B2,6,Cn1cc2c(ccc3c(=O)c(-c4ccc(C5(NC(=O)OC(C)(C)C)CCC5)cc4)c(-c4ccccc4)oc32)n1>>Cn1cc2c(ccc3c(=O)c(-c4ccc(C5(N)CCC5)cc4)c(-c4ccccc4)oc32)n1 -US20130274266A1,2,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)Cn2c1nc(Cl)c2Cl.N#Cc1ccc(C(=O)O)nc1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)Cn2c1nc(Cl)c2Cl -US20080171743A1,2,C[C@H]1COCCN1c1cc(CS(=O)(=O)C2CCCCC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(CS(=O)(=O)C2CCCCC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US05439932,6,CCN(C/C=C/C#C[Si](C)(C)C)CCOCCOc1cccc(-c2ccsc2)c1>>C#C/C=C/CN(CC)CCOCCOc1cccc(-c2ccsc2)c1 -US08168658B2,7,COC(=O)C(C#N)c1ccc(C(=O)OC(C)(C)C)cc1>>COC(=O)C(CN)c1ccc(C(=O)OC(C)(C)C)cc1 -US04017620,2,C1CCNCC1.Cc1sc2c(c1C)C(c1ccccc1)=[N+]([O-])Cc1nc(C(=O)O)nn1-2>>Cc1sc2c(c1C)C(c1ccccc1)=[N+]([O-])Cc1nc(C(=O)N3CCCCC3)nn1-2 -US20090281126A1,2,CCOC(=O)Cl.O[C@@H]1C=C[C@H](n2cnc3c(Cl)ncnc32)C1>>CCOC(=O)O[C@@H]1C=C[C@H](n2cnc3c(Cl)ncnc32)C1 -US08680108B2,1,CC(=O)c1cc(Cl)c2cccnc2c1N1CCN(C(=O)c2c(C)noc2C)CC1.[NH4+]>>Cc1noc(C)c1C(=O)N1CCN(c2c(C(C)N)cc(Cl)c3cccnc23)CC1 -US05025002,1,CCOC(=O)CCl.COP(OC)OC>>CCOC(=O)CP(=O)(OC)OC -US20080108608A1,1,Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(C#Cc2cnc(Cl)nc2)c1.NCCCN1CCCCC1>>Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(C#Cc2cnc(NCCCN3CCCCC3)nc2)c1 -US05104892,1,CN.ClCc1nc2ccccc2[nH]1>>CNCc1nc2ccccc2[nH]1 -US20080015203A1,2,CNC.O=S(=O)(Cl)c1ccc(F)c(Cl)c1>>CN(C)S(=O)(=O)c1ccc(F)c(Cl)c1 -US06174877B1,2,N#CCC(=O)O.NCc1ccccn1>>N#CCC(=O)NCc1ccccn1 -US20120028919A1,7,COc1cc(N2CCC(N3CCCC3)CC2)ccc1[N+](=O)[O-]>>COc1cc(N2CCC(N3CCCC3)CC2)ccc1N -US20090215725A1,1,O=S(=O)(c1ccccc1)n1ccc2c(CBr)cccc21.OCC1CCC2(CC1)OCCO2>>O=S(=O)(c1ccccc1)n1ccc2c(COCC3CCC4(CC3)OCCO4)cccc21 -US06211197B1,3,C=C[Mg+].O=Cc1ccccc1OCc1ccccc1>>C=CC(O)c1ccccc1OCc1ccccc1 -US20030092720A1,6,CC(C)c1csc(COc2ccn3c(=O)c(/C=C/C(=O)OC(C)(C)C)c(N4CCCC(O)C4)nc3c2)n1>>CC(C)c1csc(COc2ccn3c(=O)c(/C=C/C(=O)O)c(N4CCCC(O)C4)nc3c2)n1 -US20130109652A1,6,CCOC(=O)Cn1cc(-c2ccc(OC)cc2)ccc1=O>>COc1ccc(-c2ccc(=O)n(CC(=O)O)c2)cc1 -US20150030704A1,3,C#Cc1ccccc1C(F)(F)F.Clc1cc(OCc2ccccc2)c(OCc2ccccc2)nn1>>FC(F)(F)c1ccccc1C#Cc1cc(OCc2ccccc2)c(OCc2ccccc2)nn1 -US20130158075A1,6,CCOC(=O)C1CCC(n2ccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)n2)CC1>>O=C(Nc1ccc(-c2ccn(C3CCC(C(=O)O)CC3)n2)cc1)Nc1cccc(C(F)(F)F)c1 -US20130231306A1,1,CCOP(=O)(Cc1ccc(Nc2ncc(C(F)(F)F)c(Cl)n2)c(OC)c1)OCC.CNC(=O)c1c(N)cccc1F>>CCOP(=O)(Cc1ccc(Nc2ncc(C(F)(F)F)c(Nc3cccc(F)c3C(=O)NC)n2)c(OC)c1)OCC -US09073929B2,3,Brc1ccc2c(c1)CCc1nncn1-2.OB(O)c1cncc(C(O)(C(F)(F)F)C(F)(F)F)c1>>OC(c1cncc(-c2ccc3c(c2)CCc2nncn2-3)c1)(C(F)(F)F)C(F)(F)F -US20110003809A1,4,Nc1cc([N+](=O)[O-])cnc1N.S=C=Nc1ccccc1>>O=[N+]([O-])c1cnc2[nH]c(Nc3ccccc3)nc2c1 -US20110124618A1,6,CCOC(=O)c1cc(-c2cccc(C#N)c2)n(-c2ccc(F)c(Cl)c2)n1>>N#Cc1cccc(-c2cc(C(=O)O)nn2-c2ccc(F)c(Cl)c2)c1 -US07618959B2,1,COc1ccc2nccc(-c3ccc(CCN)nc3)c2n1.O=Cc1cc2c(cn1)OCCO2>>COc1ccc2nccc(-c3ccc(CCNCc4cc5c(cn4)OCCO5)nc3)c2n1 -US05106871,6,COC(=O)COc1ccc(CCC(=O)c2ccc(OC)c(CCC(C)C)c2O)cc1>>COc1ccc(C(=O)CCc2ccc(OCC(=O)O)cc2)c(O)c1CCC(C)C -US20070232607A1,2,COCCN.O=C(O)COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>COCCNC(=O)COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12 -US08404856B2,1,Fc1c(C(F)(F)F)ccnc1Cl.Oc1cc(Cl)cc(Br)c1>>FC(F)(F)c1ccnc(Cl)c1Oc1cc(Cl)cc(Br)c1 -US05614633,8,O=C(OO)c1cccc(Cl)c1.O=[N+]([O-])c1ccc2c(c1)C(c1ccccn1)=CC(C(F)(F)F)(C(F)(F)F)O2>>O=[N+]([O-])c1ccc2c(c1)C(c1cccc[n+]1[O-])=CC(C(F)(F)F)(C(F)(F)F)O2 -US08299267B2,1,BrCc1ccccc1.CC(C)(C)OC(=O)NCc1cccc(N)c1>>CC(C)(C)OC(=O)NCc1cccc(NCc2ccccc2)c1 -US20150210677A1,2,CS(=O)(=O)Cl.NC1=C(O)C(=O)C(c2ccc(Cl)cc2)O1>>CS(=O)(=O)OC1=C(N)OC(c2ccc(Cl)cc2)C1=O -US07439232B2,1,CC(C)I.CCc1ccc(Cc2c(OCc3ccccc3)n[nH]c2C)cc1>>CCc1ccc(Cc2c(OCc3ccccc3)nn(C(C)C)c2C)cc1 -US06559100B1,6,COC(=O)c1ccc(C=S(=O)=O)c(CC2=NOCC2)c1Cl>>O=C(O)c1ccc(C=S(=O)=O)c(CC2=NOCC2)c1Cl -US06956050B2,7,O=[N+]([O-])c1ccccc1Nc1ccc(CCO)cc1>>Nc1ccccc1Nc1ccc(CCO)cc1 -US20080269170A1,1,CN(C1CCNCC1)S(=O)(=O)c1ccc(Nc2nccc(Nc3ccc(F)c(F)c3)n2)cc1.O=CCCC(F)(F)F>>CN(C1CCN(CCCC(F)(F)F)CC1)S(=O)(=O)c1ccc(Nc2nccc(Nc3ccc(F)c(F)c3)n2)cc1 -US09056859B2,6,CC1Cc2cc(CC3OCCO3)ccc2C(=O)O1>>CC1Cc2cc(CC=O)ccc2C(=O)O1 -US20130237519A1,2,CC1(C)CC[C@H](C[NH3+])O1.O=C(O)c1ccc(F)c(NC(=O)c2cnc3cc(Br)ccn23)c1>>CC1(C)CC[C@@H](CNC(=O)c2ccc(F)c(NC(=O)c3cnc4cc(Br)ccn34)c2)O1 -US20130338133A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.FC(F)(F)CCNc1cc(Br)nn2ccnc12>>CC(C)(C)OC(=O)N(CCC(F)(F)F)c1cc(Br)nn2ccnc12 -US20150246912A1,6,CCOC(=O)Cn1ccc(C(F)(F)F)n1>>O=C(O)Cn1ccc(C(F)(F)F)n1 -US08003649B2,1,FC(F)c1nnc2ccc(N3CCNCC3)nn12.O=Cc1n[nH]c2ccccc12>>FC(F)c1nnc2ccc(N3CCN(Cc4n[nH]c5ccccc45)CC3)nn12 -US05102877,1,CC(C)(C)OC(=O)N1CC[C@@H](OS(C)(=O)=O)C1.O=C([O-])c1ccccc1>>CC(C)(C)OC(=O)N1CC[C@H](OC(=O)c2ccccc2)C1 -US06890947B2,7,CO/C(=C\c1ccc2c(ccn2Cc2nc(-c3ccccc3)oc2C)c1)C(=O)O>>COC(Cc1ccc2c(ccn2Cc2nc(-c3ccccc3)oc2C)c1)C(=O)O -US20150166527A1,6,CO[C@H]1C[C@@H](c2nc3ccc(Cl)c(C)c3[nH]2)N(C(=O)OC(C)(C)C)C1>>CO[C@@H]1CN[C@H](c2nc3ccc(Cl)c(C)c3[nH]2)C1 -US08415345B2,9,CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)c(-c2ccnc(Cl)n2)s1>>CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)c(-c2ccncn2)s1 -US20030055244A1,6,CCOC(=O)CCN1CCN(C(=O)N2CCC3(CCN(c4ccncc4)CC3)C2)CC1=O>>O=C(O)CCN1CCN(C(=O)N2CCC3(CCN(c4ccncc4)CC3)C2)CC1=O -US20120157434A1,6,C[Si](C)(C)OC(C#N)[C@@H]1Cc2ccccc2N1C(=O)OCc1ccccc1>>N#C[C@H](O)[C@@H]1Cc2ccccc2N1C(=O)OCc1ccccc1 -US07244722B2,7,O=C(O)CCc1cc(F)c(F)cc1F>>OCCCc1cc(F)c(F)cc1F -US20060178384A1,1,COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.NCCO>>COc1ccc2c(c1)CCn1c-2cc(NCCO)nc1=O -US06090813,6,O=C(C1CCN(c2ccncn2)CC1)N1CCN(Cc2ccccc2)CC1>>O=C(C1CCN(c2ccncn2)CC1)N1CCNCC1 -US07910595B2,7,O=C(Nc1ncc(Br)s1)c1ccc(Sc2ccc(O)cc2)c([N+](=O)[O-])c1>>Nc1cc(C(=O)Nc2ncc(Br)s2)ccc1Sc1ccc(O)cc1 -US08269014B2,6,COC(=O)c1sc(C#CC(C)(C)C)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCC2(CC1)OCCO2>>COC(=O)c1sc(C#CC(C)(C)C)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCC(=O)CC1 -US08063212B2,2,C1COCCN1.O=C(O)c1cnccc1Cl>>O=C(c1cnccc1Cl)N1CCOCC1 -US20130253024A1,4,CC(C)(C)OC(=O)c1ccc(-n2c(CCC#N)ccc2-c2ccccc2)cc1.C[Si](C)(C)N=[N+]=[N-]>>CC(C)(C)OC(=O)c1ccc(-n2c(CCc3nnn[nH]3)ccc2-c2ccccc2)cc1 -US05763463,2,CCc1nccc(N)c1Cl.O=C(O)Cc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1>>CCc1nccc(NC(=O)Cc2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)c1Cl -US08912329B2,2,CC(C)(C)CC(=O)Cl.c1ccc(C2CNCCO2)cc1>>CC(C)(C)CC(=O)N1CCOC(c2ccccc2)C1 -US20110269244A1,3,CC(C)(C)OC(=O)N1CCN(c2ccnc3ccc(C=O)cc23)CC1.O=C1CSC(Nc2c(Cl)cccc2Cl)=N1>>CC(C)(C)OC(=O)N1CCN(c2ccnc3ccc(/C=C4\SC(Nc5c(Cl)cccc5Cl)=NC4=O)cc23)CC1 -US06531502B1,3,CC(=O)c1ccc2c(c1)CC(=O)N2.Cc1c(C=O)[nH]c2ccccc12>>CC(=O)c1ccc2c(c1)C(=Cc1[nH]c3ccccc3c1C)C(=O)N2 -US06645980B1,2,Clc1ccc(C2(CN3CCCC(CNc4ccccc4)C3)CCC2)cc1.O=C(Cl)C1CCC1>>O=C(C1CCC1)N(CC1CCCN(CC2(c3ccc(Cl)cc3)CCC2)C1)c1ccccc1 -US20020037907A1,2,CN.O=C(O)c1c(F)cccc1F>>CNC(=O)c1c(F)cccc1F -US20060247250A1,2,COc1ccc(Cl)c(C(=O)O)c1.Nc1cnc(Nc2ccc(C(=O)NCCN3CCCC3)nc2)nc1>>COc1ccc(Cl)c(C(=O)Nc2cnc(Nc3ccc(C(=O)NCCN4CCCC4)nc3)nc2)c1 -US20150111734A1,2,CC(=O)Cl.CN(C(=O)[C@H]1C=C[C@@H](N)C1)c1cn(-c2cccnc2)nc1Cl>>CC(=O)N[C@@H]1C=C[C@H](C(=O)N(C)c2cn(-c3cccnc3)nc2Cl)C1 -US20090143354A1,2,CS(=O)(=O)Cl.O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(N3CCC[C@@H](O)C3)ccc12>>CS(=O)(=O)O[C@@H]1CCCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)C1 -US09079854B2,1,CC(C)(C)CC(=O)NN.CCCCCN1C(=O)C(=O)c2ccc(OC)cc21>>CCCCCN1C(=O)/C(=N\NC(=O)CC(C)(C)C)c2ccc(OC)cc21 -US05521170,2,CCOC(=O)CN1C(=O)CCNc2ccccc21.Cc1ccccc1-c1ccccc1C(=O)Nc1ccc(C(=O)O)cc1Cl>>CCOC(=O)CN1C(=O)CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3C)c(Cl)c2)c2ccccc21 -US20150018343A1,6,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccc(F)cc1O[C@@H]1CCN(C(=O)OC(C)(C)C)[C@@H](C(F)(F)F)C1)C3>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccc(F)cc1O[C@@H]1CCN[C@@H](C(F)(F)F)C1)C3 -US20090111995A1,1,CC(C)[C@H](N)C(=O)O.O=Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CC(C)[C@H](NCc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)C(=O)O -US07705023B2,1,CC(C)Oc1ccc(B(O)O)cc1.CCOC(=O)c1cc2cc(Br)ccc2[nH]1>>CCOC(=O)c1cc2cc(Br)ccc2n1-c1ccc(OC(C)C)cc1 -US20070249670A1,6,CCCC[C@H](NC(=O)c1nc2ccccc2cc1NC(=O)Nc1c(Cl)cccc1Cl)C(=O)OC>>CCCC[C@H](NC(=O)c1nc2ccccc2cc1NC(=O)Nc1c(Cl)cccc1Cl)C(=O)O -US20110065734A1,2,CC(C)(C)OC(=O)Nc1ccccc1N.COC(=O)c1cccc(/C=C/C(=O)O)c1>>COC(=O)c1cccc(/C=C/C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)c1 -US08470816B2,2,CC(=O)N1CCC(C(=O)O)CC1.CN(C(=O)c1cccs1)[C@@H]1CCNC[C@H]1c1ccccc1>>CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3cccs3)[C@H](c3ccccc3)C2)CC1 -US06933311B2,2,NCc1cc(F)c(N2CCOCC2)c(F)c1.O=C=Nc1cccc2cnccc12>>O=C(NCc1cc(F)c(N2CCOCC2)c(F)c1)Nc1cccc2cnccc12 -US05686482,7,COC(=O)c1cc(C(C)=O)c(OC)cc1OC>>CCc1cc(C(=O)OC)c(OC)cc1OC -US20150218150A1,2,CN1Cc2cc(-c3ccc(-c4cncc(N)c4)s3)ccc2C1=O.O=S(=O)(Cl)c1ccc(Br)cc1>>CN1Cc2cc(-c3ccc(-c4cncc(NS(=O)(=O)c5ccc(Br)cc5)c4)s3)ccc2C1=O -US20150203472A1,3,Fc1ccc(-n2cnc3ccc(Br)cc32)c(F)c1.OB(O)c1ccnn1-c1ccc(C(F)(F)F)cc1>>Fc1ccc(-n2cnc3ccc(-c4ccnn4-c4ccc(C(F)(F)F)cc4)cc32)c(F)c1 -US20020165234A1,1,CC(C)(N)Cc1ccc(O)cc1.NC(=O)c1ccc(Cl)nc1>>CC(C)(N)Cc1ccc(Oc2ccc(C(N)=O)cn2)cc1 -US20070249670A1,2,Nc1cc(-c2ccc(F)cc2)sc1C(=O)O.O=C=Nc1c(Cl)cccc1Cl>>O=C(Nc1cc(-c2ccc(F)cc2)sc1C(=O)O)Nc1c(Cl)cccc1Cl -US06107329,6,CN(C)C(=O)[C@H](Cc1ccc(N)cc1)NC(=O)OC(C)(C)C>>CN(C)C(=O)[C@@H](N)Cc1ccc(N)cc1 -US20100144760A1,2,CC(C)(C)[Si](OC[C@@H]1C[C@H]2C[C@H]2CN1)(c1ccccc1)c1ccccc1.Cc1ccc(-c2ncccn2)c(C(=O)O)n1>>Cc1ccc(-c2ncccn2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)n1 -US06455725B1,7,COC(=O)C=Cc1cc(Cl)ccc1C(=O)O>>COC(=O)CCc1cc(Cl)ccc1C(=O)O -US05039806,8,CCCCCCCOc1c(C)cc2[nH]c(SCc3ncc(C)c(OC)c3C)nc2c1C.O=C(OO)c1cccc(Cl)c1>>CCCCCCCOc1c(C)cc2[nH]c(S(=O)Cc3ncc(C)c(OC)c3C)nc2c1C -US08299267B2,4,COC(=O)c1cc(N)cc(C(=O)OC)c1.ICCCCI>>COC(=O)c1cc(C(=O)OC)cc(N2CCCC2)c1 -US07495007B2,1,CC(C)(C)[Si](C)(C)OCCBr.CCc1ccc(O)c(C=O)c1>>CCc1ccc(OCCO[Si](C)(C)C(C)(C)C)c(C=O)c1 -US04658049,6,C=CCOC(C)C(=O)OCC>>C=CCOC(C)C(=O)O -US20120149721A1,2,CCC(=O)Cl.Cc1[nH]c2c(-c3cc(F)ccc3OCC3CC3)ncnc2c1C(=O)N[C@@H]1CCNC1>>CCC(=O)N1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4cc(F)ccc4OCC4CC4)ncnc23)C1 -US07622481B2,1,CI.O=c1[nH]ccc2cccc(Br)c12>>Cn1ccc2cccc(Br)c2c1=O -US20100267561A1,6,COc1c(C)nn(C)c(=O)c1-n1nc(-c2ccc(C(F)(F)F)cc2)cc1C>>Cc1nn(C)c(=O)c(-n2nc(-c3ccc(C(F)(F)F)cc3)cc2C)c1O -US04133880,2,CCCCO.COc1cc2ccc(S(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)O)cc2cc1OC>>CCCCOC(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c1ccc2cc(OC)c(OC)cc2c1 -US20050176720A1,3,OB(O)c1cccnc1.Oc1ccc(Br)cc1>>Oc1ccc(-c2cccnc2)cc1 -US20100267634A1,1,CC(C)(C)OC(=O)N1CCC[C@H]1c1nc2cc(CBr)ccc2[nH]1.O=[N+]([O-])c1ccc(CNc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1c1nc2cc(CN(Cc3ccc([N+](=O)[O-])cc3)c3ccccc3)ccc2[nH]1 -US05500405,2,CC(=O)Cl.O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1O>>CC(=O)Oc1c(Cl)cc(Cl)cc1S(=O)(=O)Cl -US07557127B2,2,Nc1cccc(N)c1.O=C(O)C1CCCCC1>>Nc1cccc(NC(=O)C2CCCCC2)c1 -US09067918B2,2,CNc1nccc(-c2cc3cc(C(=O)O)ccc3[nH]2)n1.NC(=O)[C@@H](N)CN(c1ccccc1)c1ncccn1>>CNc1nccc(-c2cc3cc(C(=O)N[C@@H](CN(c4ccccc4)c4ncccn4)C(N)=O)ccc3[nH]2)n1 -US20140200225A1,2,C[C@@H]1CC[C@@H](C(=O)O)CC1.N#Cc1ccc(Oc2cc(N)cc(Oc3ccc(C#N)cc3)c2)cc1>>C[C@@H]1CC[C@@H](C(=O)Nc2cc(Oc3ccc(C#N)cc3)cc(Oc3ccc(C#N)cc3)c2)CC1 -US20080139558A1,2,O=C(O)c1cccnc1.O=c1cc(CNc2ccccc2)c2ccccc2[nH]1>>O=C(c1cccnc1)N(Cc1cc(=O)[nH]c2ccccc12)c1ccccc1 -US20070054916A1,3,CNc1ncc2cc(Br)ccc2n1.Cc1ccc(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)cc1B1OC(C)(C)C(C)(C)O1>>CNc1ncc2cc(-c3cc(C(=O)Nc4ccc(F)c(C(F)(F)F)c4)ccc3C)ccc2n1 -US20080188506A1,7,Cc1cccc(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1>>Cc1cccc(C2NCCC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1 -US20150175570A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc(N2CCN[C@H](C)C2)ccc1[N+](=O)[O-]>>Cc1nc(N2CCN(C(=O)OC(C)(C)C)[C@H](C)C2)ccc1[N+](=O)[O-] -US08415333B2,6,CC(C)(C)OC(=O)NCc1ccc(N=[N+]=[N-])c(I)c1>>[N-]=[N+]=Nc1ccc(CN)cc1I -US08129424B2,6,CC(C)(C)[Si](C)(C)OCCc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1>>OCCc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1 -US07332497B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ncnc2c1c(I)nn2C1CCCNC1>>CC(C)(C)OC(=O)N1CCCC(n2nc(I)c3c(N)ncnc32)C1 -US07365085B2,4,C[Si](C)(C)N=[N+]=[N-].N#CCc1cccc(OCc2ccccc2)c1>>c1ccc(COc2cccc(Cc3nnn[nH]3)c2)cc1 -US20070060563A1,1,CCC#CCBr.O=C(O[C@H]1CN2CCC1CC2)C(O)(c1cccs1)c1cccs1>>CCC#CC[N+]12CCC(CC1)[C@@H](OC(=O)C(O)(c1cccs1)c1cccs1)C2 -US08952169B2,2,NS(=O)(=O)N1CCC1.O=C(O)c1cc(C2CC2)c(OCC23CC4(F)CC(F)(CC(F)(C4)C2)C3)cc1F>>O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4(F)CC(F)(CC(F)(C4)C2)C3)cc1F -US05209868,1,CCCCC[C@@H]1CC[C@@H](C(=O)O)CC1.O[C@@H]1CC[C@@H](C(F)(F)F)CC1>>CCCCC[C@@H]1CC[C@@H](C(=O)O[C@@H]2CC[C@@H](C(F)(F)F)CC2)CC1 -US06166011,1,CC(=O)Oc1ccc2nc(Cl)oc2c1.O=C(OCc1ccccc1)[C@@H]1CCCC[NH2+]1>>CC(=O)Oc1ccc2nc(N3CCCC[C@H]3C(=O)OCc3ccccc3)oc2c1 -US20110183954A1,1,COC[C@H](N)c1ncc(F)cc1F.Cn1cnc(Nc2nc(Cl)nc(Cl)n2)c1>>COC[C@H](Nc1nc(Cl)nc(Nc2cn(C)cn2)n1)c1ncc(F)cc1F -US05013478,7,N#Cc1ccc(C2CCC(C=O)CC2)cc1>>N#Cc1ccc([C@@H]2CC[C@@H](CO)CC2)cc1 -US20090270350A1,7,COC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccc(F)cc3C#N)c(Cl)c2=O)c1>>COC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccc(F)cc3CN)c(Cl)c2=O)c1 -US20050245592A1,2,CCOc1cc(C)c(Br)cc1C(=O)O.CN>>CCOc1cc(C)c(Br)cc1C(=O)NC -US09115079B2,3,O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)OCc1ccccc1.O=C1CCC2(CC1)OCCO2>>O=C(C=C1CCC2(CC1)OCCO2)OCc1ccccc1 -US20130281399A1,2,COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCNCC4)cc3)nc2c1.O=C(O)c1ccncc1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCN(C(=O)c5ccncc5)CC4)cc3)nc2c1 -US20050143382A1,1,NNc1nc2nonc2nc1Nc1ccccc1.O=Cc1c[nH]c2ccccc12>>C(=NNc1nc2nonc2nc1Nc1ccccc1)c1c[nH]c2ccccc12 -US20060030612A1,1,CI.Fc1cc(F)c(Cn2nc3c(C(F)(F)F)cccc3c2-c2cccc(-c3cc4cc(F)ccc4[nH]3)c2)c(F)c1>>Cn1c(-c2cccc(-c3c4cccc(C(F)(F)F)c4nn3Cc3c(F)cc(F)cc3F)c2)cc2cc(F)ccc21 -US20130079337A1,6,O=c1c2cnn(C3CCCCO3)c2c2ccc(-c3cccc[n+]3[O-])cc2n1CC(F)(F)F>>O=c1c2cn[nH]c2c2ccc(-c3cccc[n+]3[O-])cc2n1CC(F)(F)F -US20090298826A1,2,COc1cc(O)ccc1-c1ccc2c(c1COC(=O)c1ccc(C)s1)C(C)=CC(C)(C)N2.O=S(=O)(Cl)CCC(F)(F)F>>COc1cc(OS(=O)(=O)CCC(F)(F)F)ccc1-c1ccc2c(c1COC(=O)c1ccc(C)s1)C(C)=CC(C)(C)N2 -US20080188484A1,2,CC(C)N1CCC(Oc2cc3cc(C(=O)O)[nH]c3cc2Br)CC1.CS(=O)(=O)N1CCNCC1>>CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCN(S(C)(=O)=O)CC4)[nH]c3cc2Br)CC1 -US20130296363A1,1,Nc1nccs1.O=S(c1ccc(F)cc1)c1cc2ccccc2c(Br)n1>>O=S(c1ccc(F)cc1)c1cc2ccccc2c(Nc2nccs2)n1 -US20050209290A1,1,Cc1cc(O)ccc1COCCn1ccnn1.FC(F)Oc1ccc(C=Cc2nc(CCl)co2)cc1>>Cc1cc(OCc2coc(C=Cc3ccc(OC(F)F)cc3)n2)ccc1COCCn1ccnn1 -US20150080364A1,6,CC(C)(C)OC(=O)N1CCN(Cc2cc(Cl)ccc2N2CCOCC2)CC1>>Clc1ccc(N2CCOCC2)c(CN2CCNCC2)c1 -US20100137298A1,6,CCOC(=O)c1oc2cccc(NC(=O)OC(C)(C)C)c2c1C>>CCOC(=O)c1oc2cccc(N)c2c1C -US04307072,2,CC(=O)OC(C)=O.Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I>>CC(=O)Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I -US20050014810A1,6,O=C(O)C1CCN(c2cccc(C3OCCO3)c2)CC1>>O=Cc1cccc(N2CCC(C(=O)O)CC2)c1 -US20150152088A1,3,C#Cc1cc(C(=O)Nc2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)ccc1C.CNc1ncc2ccc(Br)cc2n1>>CNc1ncc2ccc(C#Cc3cc(C(=O)Nc4ccc(CN5CCN(CCO)CC5)c(C(F)(F)F)c4)ccc3C)cc2n1 -US08063071B2,3,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1.Nc1cccc(B(O)O)c1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(N)c4)cc23)CC1 -US20100048532A1,6,Cc1nc2cc(C(=O)N(C)C)c3c(c2n1CCCO[Si](C)(C)C(C)(C)C)OC(c1ccc(F)cc1)CC3>>Cc1nc2cc(C(=O)N(C)C)c3c(c2n1CCCO)OC(c1ccc(F)cc1)CC3 -US04131677,7,O=[N+]([O-])c1ccccc1-c1nc2cccnc2o1>>Nc1ccccc1-c1nc2cccnc2o1 -US20060166857A1,7,CC(=O)C=C(C)CCC=C(C)C>>CC(=O)CC(C)CCC=C(C)C -US20100004438A1,2,CCOC(=O)CNc1ccc(Oc2ccc([N+](=O)[O-])cn2)c(OC)c1.CS(=O)(=O)Cl>>CCOC(=O)CN(c1ccc(Oc2ccc([N+](=O)[O-])cn2)c(OC)c1)S(C)(=O)=O -US20090131418A1,6,CC(C)COc1ccc(CN2C(=O)COC3(CCN(C(=O)OCc4ccccc4)CC3)C2Cc2ccc(F)cc2)cc1>>CC(C)COc1ccc(CN2C(=O)COC3(CCNCC3)C2Cc2ccc(F)cc2)cc1 -US20140148448A1,2,C[Si](C)(C)CCOCn1cc(C#N)nc1C(=O)[O-].Nc1ccc(CCS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1>>C[Si](C)(C)CCOCn1cc(C#N)nc1C(=O)Nc1ccc(CCS(=O)(=O)N2CCOCC2)cc1C1=CCCCC1 -US05633279,6,COCCOCOc1c(C/C=C(\C)CCC(=O)OC)c(OC)c(C)c2c1C(=O)OC2>>COCCOCOc1c(C/C=C(\C)CCC(=O)O)c(OC)c(C)c2c1C(=O)OC2 -US04900751,2,COc1ccc(CCN)cc1OC.Cc1ccccc1C(=S)Cl>>COc1ccc(CCNC(=S)c2ccccc2C)cc1OC -US08193202B2,6,COCC1(C(=O)Nc2cccc(OC(=O)N(C)C)c2)CCN(C(=O)OC(C)(C)C)CC1>>COCC1(C(=O)Nc2cccc(OC(=O)N(C)C)c2)CCNCC1 -US20100016337A1,2,C1CNC1.O=C(O)CNc1nc(-c2ccc(F)cc2)cs1>>O=C(CNc1nc(-c2ccc(F)cc2)cs1)N1CCC1 -US08324216B2,2,Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O.Fc1ccccc1N1CCNCC1>>Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccccc2F)CC1 -US08765771B2,2,CS(=O)(=O)c1ccc(Nc2ncnc3c(C4CCNCC4)coc23)c(F)c1.O=C(Cl)OCc1ccccc1>>CS(=O)(=O)c1ccc(Nc2ncnc3c(C4CCN(C(=O)OCc5ccccc5)CC4)coc23)c(F)c1 -US20120157434A1,2,CC(=O)NC[C@@H]1OC(=O)N2c3ccc(-c4ccc(-n5cnnn5)nc4)cc3C[C@@H]12.O=C(Cl)OCCl>>CC(=O)N(C[C@@H]1OC(=O)N2c3ccc(-c4ccc(-n5cnnn5)nc4)cc3C[C@@H]12)C(=O)OCCl -US07256287B2,2,Nc1cc2nc(-c3ccc([N+](=O)[O-])cc3)[nH]c2cn1.O=C(Cl)C1CCCCC1>>O=C(Nc1cc2nc(-c3ccc([N+](=O)[O-])cc3)[nH]c2cn1)C1CCCCC1 -US20090264445A1,6,COC(=O)[C@H](CC(C)C)N1CC(Oc2ccc(CC(C)(C)O)cc2)=CC1=O>>CC(C)C[C@@H](C(=O)O)N1CC(Oc2ccc(CC(C)(C)O)cc2)=CC1=O -US04605764,1,CC(C)CCN(CCl)C(=O)C(Cl)Cl.CCOCCO>>CCOCCOCN(CCC(C)C)C(=O)C(Cl)Cl -US20070232632A1,1,CCOC(=O)N=S(C)(=O)c1ccc(N)cc1.C[C@H](CO)Nc1nc(Cl)ncc1-c1cccs1>>CCOC(=O)N=S(C)(=O)c1ccc(Nc2ncc(-c3cccs3)c(N[C@H](C)CO)n2)cc1 -US07001921B1,6,COc1cc(CC(=O)OC(C)(C)C)ccc1NC(=O)Nc1ccccc1>>COc1cc(CC(=O)O)ccc1NC(=O)Nc1ccccc1 -US07214690B2,1,C=CCBr.CC[C@@H]1COc2c(ccc3nc(OC(C)C)cc(C(F)(F)F)c23)N1>>C=CCN1c2ccc3nc(OC(C)C)cc(C(F)(F)F)c3c2OC[C@H]1CC -US20040087798A1,1,CC(=O)C(C)Br.O=CNc1cc(Cl)cc(NC=O)c1>>CC(=O)C(C)N(C=O)c1cc(Cl)cc(NC=O)c1 -US20050143418A1,1,COC(=O)CCBr.Cc1cccc(S)c1>>COC(=O)CCSc1cccc(C)c1 -US05773446,6,COC(=O)CCCC1C=Cc2c(C=O)cc(OC)c(OC)c2O1>>COc1cc(C=O)c2c(c1OC)OC(CCCC(=O)O)C=C2 -US06548494B1,1,C1=CCNC1.CC(C)CC(Cl)c1ccc(C2=NC=C3C=CC(=O)NC4=C3N2CC4)cc1>>CC(C)CC(c1ccc(C2=NC=C3C=CC(=O)NC4=C3N2CC4)cc1)N1CC=CC1 -US20080255358A1,6,Cc1cccc(C)c1CNc1cc(-n2cc(C(=O)OCc3ccccc3)ccc2=O)cn2c(C)c(C)nc12>>Cc1cccc(C)c1CNc1cc(-n2cc(C(=O)O)ccc2=O)cn2c(C)c(C)nc12 -US20140303156A1,2,Nc1ccsc1.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1ccsc1 -US04526896,2,CC(=O)OC(C)=O.NCc1ccc2oc([N+](=O)[O-])c(-c3ccccc3)c2c1>>CC(=O)NCc1ccc2oc([N+](=O)[O-])c(-c3ccccc3)c2c1 -US20090143364A1,2,CCOc1cc(C(C)(C)C#N)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCN1CCNCC1>>CCOc1cc(C(C)(C)C#N)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CCS(C)(=O)=O)CC1 -US20140018533A1,3,CCOC(=O)C1=C(Nc2ccccc2)OCC1=O.O=Cc1c[nH]c2ncc(Cl)cc12>>CCOC(=O)C1=C(Nc2ccccc2)OC(=Cc2c[nH]c3ncc(Cl)cc23)C1=O -US20040143001A1,1,CCCCCCCCCCCBr.Oc1ccc(-c2c3nc(c(-c4ccc(O)cc4)c4ccc([nH]4)c(-c4ccc(O)cc4)c4nc(c(-c5ccc(O)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1>>CCCCCCCCCCCOc1ccc(-c2c3nc(c(-c4ccc(O)cc4)c4ccc([nH]4)c(-c4ccc(O)cc4)c4nc(c(-c5ccc(O)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1 -US20060074086A1,7,CC(C)(/C=C/C#N)c1cccc(OCc2ccccc2)c1>>CC(C)(/C=C/CN)c1cccc(OCc2ccccc2)c1 -US06420390B1,2,CCCCCCCCCC(=O)Cl.O=C1c2ccccc2C(O)N1CCN1CCC(c2noc3cc(F)ccc23)CC1>>CCCCCCCCCC(=O)OC1c2ccccc2C(=O)N1CCN1CCC(c2noc3cc(F)ccc23)CC1 -US06743808B1,2,CN(C)C(=O)Cl.Nc1ccc2c(c1)C(CN1CCC(c3ccc(F)cc3)CC1)CC2>>CN(C)C(=O)Nc1ccc2c(c1)C(CN1CCC(c3ccc(F)cc3)CC1)CC2 -US09120749B2,3,CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(N2CCN(C)CC2)nc1.CC1(C)OB(c2cc(F)c(O)c(Cl)c2)OC1(C)C>>CC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCN(C)CC2)nc1 -US05506261,7,C[C@H](C#Cc1ccc(Cc2ccc(F)cc2)s1)N(O)C(N)=O>>C[C@H](/C=C\c1ccc(Cc2ccc(F)cc2)s1)N(O)C(N)=O -US20130109696A1,2,COc1ccc(CNc2nncs2)c(OC)c1.O=S(=O)(Cl)c1cc(Cl)c(F)cc1F>>COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1 -US07625902B2,2,O=C(O)C1CN(S(=O)(=O)c2ccccc2)C(=O)N1c1ccccc1Cl.c1ccc2oc(N3CCNCC3)nc2c1>>O=C(C1CN(S(=O)(=O)c2ccccc2)C(=O)N1c1ccccc1Cl)N1CCN(c2nc3ccccc3o2)CC1 -US06451734B1,1,COC(=O)CBr.Cn1nc(Cc2ccc(O)c(Cl)c2Cl)c(Cl)c1OC(F)F>>COC(=O)COc1ccc(Cc2nn(C)c(OC(F)F)c2Cl)c(Cl)c1Cl -US20150038528A1,6,COC(=O)C[C@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1cccnc1>>N#Cc1nc(C(=O)N[C@@H](CC(=O)O)c2cccnc2)c(O)c2ccc(Oc3ccccc3)cc12 -US08134004B2,9,CC(=O)c1ccc2[nH]ncc2c1.NO>>CC(=NO)c1ccc2[nH]ncc2c1 -US20100160317A1,3,CN(C)C=O.Cc1c[nH]c2c1C(=O)N(C[C@H](O)CN1CCOCC1)CC2>>Cc1c(C=O)[nH]c2c1C(=O)N(C[C@H](O)CN1CCOCC1)CC2 -US08546427B2,2,CC1(C)CC(c2cccc(N)c2)Nc2ccc(C(F)(F)F)cc21.CS(=O)(=O)Cl>>CC1(C)CC(c2cccc(NS(C)(=O)=O)c2)Nc2ccc(C(F)(F)F)cc21 -US20130079345A1,3,COc1cc(C(F)(F)F)ccc1B(O)O.NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1>>COc1cc(C(F)(F)F)ccc1-c1ncnc(Nc2cccc(CS(N)(=O)=O)c2)n1 -US20080096892A1,7,O=C(NCc1cccc([N+](=O)[O-])c1)Nc1ccc(Cl)c(C(F)(F)F)c1>>Nc1cccc(CNC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)c1 -US06015812,2,CC(C)(C)OC(=O)NC(Cc1ccc(C#N)cc1)C(=O)O.CC1C=CC(C)N1>>CC1C=CC(C)N1C(=O)C(Cc1ccc(C#N)cc1)NC(=O)OC(C)(C)C -US20040242890A1,1,BrCc1cccc(I)c1.NC(=O)NC1NC(=O)NC1=O>>NC(=O)NC1NC(=O)N(Cc2cccc(I)c2)C1=O -US20110200586A1,6,COC(=O)C1CC(N(C)C(=O)C(F)(F)F)CN1C(=O)OC(C)(C)C>>CNC1CC(C(=O)OC)N(C(=O)OC(C)(C)C)C1 -US06187779B1,3,C=CCCCCC.CCCOc1ccccc1-c1nc2c(I)cccc2c(=O)[nH]1>>CCCCCC=Cc1cccc2c(=O)[nH]c(-c3ccccc3OCCC)nc12 -US06303659B2,2,Cc1ccc(C)c(C(=O)O)c1.NCCC12CC3CC(CC(C3)C1)C2>>Cc1ccc(C)c(C(=O)NCCC23CC4CC(CC(C4)C2)C3)c1 -US20070185152A1,1,CC1(C)OB(c2ccccc2O)OC1(C)C.Fc1cccc(CBr)c1>>CC1(C)OB(c2ccccc2OCc2cccc(F)c2)OC1(C)C -US07179823B1,6,CCOC(=O)CCc1cn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)nc1OC(C)C>>Cc1oc(-c2ccccc2)nc1COc1ccc(Cn2cc(CCC(=O)O)c(OC(C)C)n2)cc1 -US07560558B2,1,COc1cc2nccc(Cl)c2cc1OC.Cc1nc2ccncc2cc1O>>COc1cc2nccc(Oc3cc4cnccc4nc3C)c2cc1OC -US20080207634A1,7,O=Cc1cn2c(F)cccc2n1>>OCc1cn2c(F)cccc2n1 -US06403589B1,1,CNC(=O)C1CN(CC(=O)Nc2c(C)cc(C)cc2C)CCN1.Fc1ccc(C(CCCI)c2ccc(F)cc2)cc1>>CNC(=O)C1CN(CC(=O)Nc2c(C)cc(C)cc2C)CCN1CCCC(c1ccc(F)cc1)c1ccc(F)cc1 -US20150210697A1,1,CC(C)(C)OC(=O)N1CCOC(c2cc(C#N)cc(N)c2Cl)C1.COc1ccc(CN(c2nc(Cl)nn3c(C#N)cnc23)C2CC2)cc1>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(C4CN(C(=O)OC(C)(C)C)CCO4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1 -US20060217374A1,4,CCOC(=O)CC(=O)C(Br)CC.NC(=S)c1ccc(C(F)(F)F)cc1>>CCOC(=O)Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CC -US20140243374A1,6,COC(=O)c1ccc(CN(CC2CCOCC2)S(=O)(=O)c2ccc(Cl)cc2)cc1>>O=C(O)c1ccc(CN(CC2CCOCC2)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20150045378A1,3,C=CC(=O)OC.COc1nc(Cl)cc(Cl)n1>>COC(=O)C=Cc1cc(Cl)nc(OC)n1 -US20120245136A1,7,COC(=O)[C@H](C)OC1CC2(CCN(C(=O)c3ccc(OC(C)C)c(OC)c3)CC2)Oc2ccccc21>>COc1cc(C(=O)N2CCC3(CC2)C[C@@H](O[C@@H](C)CO)c2ccccc2O3)ccc1OC(C)C -US20120245136A1,7,COC(=O)[C@H](C)OC1CC2(CCN(C(=O)c3ccc(OC(C)C)c(OC)c3)CC2)Oc2ccccc21>>COc1cc(C(=O)N2CCC3(CC2)C[C@H](O[C@@H](C)CO)c2ccccc2O3)ccc1OC(C)C -US05002966,6,COC(=O)c1ccc(CCOCCCCCCNCC(O)c2cc(Cl)c(N)c(Cl)c2)s1>>Nc1c(Cl)cc(C(O)CNCCCCCCOCCc2ccc(C(=O)O)s2)cc1Cl -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1ccc2c(F)cccc2c1C=O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3c(F)cccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US20150141409A1,5,COCCl.O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1>>COCOC(=O)C(Cc1cc(=O)[nH]c2ccccc12)NC(=O)c1ccc(Cl)cc1 -US20130274272A1,1,COc1ccc(CBr)cc1.Cc1cnc(Cl)cc1-n1c(C)cc(O)cc1=O>>COc1ccc(COc2cc(C)n(-c3cc(Cl)ncc3C)c(=O)c2)cc1 -US20090286768A1,1,COc1cc(Br)ccc1O.OB(O)c1ccccc1>>COc1cc(Br)ccc1Oc1ccccc1 -US20140314669A1,6,CC(C)(C)OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cncc(OCc2ccccc2)c1>>CC(C)(C)OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cncc(O)c1 -US07964591B2,1,O=C(NCCc1cccc(Cl)c1)c1ccc(Cl)nn1.O=C(c1ccccc1C(F)(F)F)N1CCNCC1>>O=C(NCCc1cccc(Cl)c1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 -US04332948,1,CC(C=O)=Cc1ccccc1.CN(N)c1ccccc1>>CC(C=NN(C)c1ccccc1)=Cc1ccccc1 -US06777428B1,2,CN1CCC(C(=O)c2cccc(N)c2)CC1.O=C(Cl)c1ccc(I)cc1>>CN1CCC(C(=O)c2cccc(NC(=O)c3ccc(I)cc3)c2)CC1 -US20110086889A1,2,COc1ccc(Cn2nccc2N)cc1.Cc1cccc(-n2nnnc2SCC(=O)O)c1C>>COc1ccc(Cn2nccc2NC(=O)CSc2nnnn2-c2cccc(C)c2C)cc1 -US07071175B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc(N)ccc1Br>>Cc1nc(NC(=O)OC(C)(C)C)ccc1Br -US07030130B2,6,COc1cc(Cc2cnc(N)nc2N)c2cc(C3(c4ccccc4)OCCO3)oc2c1OC>>COc1cc(Cc2cnc(N)nc2N)c2cc(C(=O)c3ccccc3)oc2c1OC -US20100286161A1,1,CNC.Cc1cc(C)n(-c2cnc(CO)c(Nc3ccc(Cl)cc3)n2)n1>>Cc1cc(C)n(-c2cnc(CN(C)C)c(Nc3ccc(Cl)cc3)n2)n1 -US20090149501A1,3,CC1(C)C(C(=O)Cl)C1(C)C.Fc1c(F)c(F)c2[nH]ccc2c1F>>CC1(C)C(C(=O)c2c[nH]c3c(F)c(F)c(F)c(F)c23)C1(C)C -US07419988B2,3,CCn1cc(B2OC(C)(C)C(C)(C)O2)c(-c2ccc([N+](=O)[O-])cc2)n1.O=S(=O)(c1ccccc1)n1c(-c2cccc(CO)c2)cc2c(Br)ccnc21>>CCn1cc(-c2ccnc3c2cc(-c2cccc(CO)c2)n3S(=O)(=O)c2ccccc2)c(-c2ccc([N+](=O)[O-])cc2)n1 -US20120121540A1,6,COC(=O)Cc1c(C(=O)NCc2cccs2)nc2c(C(F)(F)F)cc(-c3ccoc3)cn12>>O=C(O)Cc1c(C(=O)NCc2cccs2)nc2c(C(F)(F)F)cc(-c3ccoc3)cn12 -US20090012063A1,3,Cn1c(-c2cccc(C(F)(F)F)c2)nc(I)c1C(=O)N1CCC(N2CCCC2)CC1.OB(O)c1cccnc1>>Cn1c(-c2cccc(C(F)(F)F)c2)nc(-c2cccnc2)c1C(=O)N1CCC(N2CCCC2)CC1 -US04168269,2,CCC(=O)Cl.O=C1Nc2ccccc2Nc2cscc21>>CCC(=O)N1c2ccccc2NC(=O)c2cscc21 -US06407217B1,6,CCc1cnc(C2=NC(C)(C(C)C)C(=O)N2)c(C(=O)NCCCCCC(=O)OC)c1>>CCc1cnc(C2=NC(C)(C(C)C)C(=O)N2)c(C(=O)NCCCCCC(=O)O)c1 -US20080119518A1,1,COc1cccc(OCc2ccccc2)c1CC=O.NC(=O)c1ccc2ccn(C3CCNCC3)c2c1>>COc1cccc(OCc2ccccc2)c1CCN1CCC(n2ccc3ccc(C(N)=O)cc32)CC1 -US09096600B2,2,CC(=O)Cl.Cc1cc(O)ccc1F>>CC(=O)Oc1ccc(F)c(C)c1 -US20040259912A1,7,COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccccc1)c1ccc(C(F)(F)F)cc1>>COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccc(C(F)(F)F)cc1 -US20150133424A1,6,COc1ccc(Cn2c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c3n(-c3cccc(CCC(N)=O)c3)c2=O)cc1>>Cc1c(=O)n(C)c(Nc2ccc(I)cc2F)c2c(=O)[nH]c(=O)n(-c3cccc(CCC(N)=O)c3)c12 -US08759535B2,6,Cn1c(Nc2nc3ccc(OC(F)(F)F)cc3s2)nc2cc(C(=O)NCC(=O)N3CCN(C(=O)OC(C)(C)C)CC3)ccc21>>Cn1c(Nc2nc3ccc(OC(F)(F)F)cc3s2)nc2cc(C(=O)NCC(=O)N3CCNCC3)ccc21 -US04329367,7,CC(Cc1ccc(OCc2ccccc2)cc1)NC(=O)CC(c1ccccc1)c1ccccc1>>CC(Cc1ccc(OCc2ccccc2)cc1)NCCC(c1ccccc1)c1ccccc1 -US07291643B2,1,CCCI.CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)[nH]2)cc1>>CCCn1c(C#N)ccc1-c1ccc(NS(=O)(=O)CC)cc1 -US07572801B2,1,Cc1ccnc2nc(Cl)[nH]c(=O)c12.OCCCOc1ccccc1Cl>>Cc1ccnc2nc(OCCCOc3ccccc3Cl)[nH]c(=O)c12 -US20010034445A1,6,CCOC(=O)Cc1cccc(N)n1>>Nc1cccc(CC(=O)O)n1 -US08563576B2,3,CON(C)C(=O)c1cccnc1F.Cc1sc(N2CCN(C(=O)OC(C)(C)C)[C@@H](CC(C)C)C2)nc1Br>>Cc1sc(N2CCN(C(=O)OC(C)(C)C)[C@@H](CC(C)C)C2)nc1C(=O)c1cccnc1F -US05603959,2,O=C(O)c1ccccc1O.OCC(Cl)(Cl)Cl>>O=C(OCC(Cl)(Cl)Cl)c1ccccc1O -US20080312234A1,2,CS(=O)(=O)Nc1ccc(CN)cc1F.O=C(O)C=Cc1ccc(C(F)(F)F)nc1OC1CCOC1>>CS(=O)(=O)Nc1ccc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2OC2CCOC2)cc1F -US20080318963A1,2,CCOC(=O)Nc1nc2cc(C)ccc2nc1OC.Clc1ccccc1N1CCNCC1>>COc1nc2ccc(C)cc2nc1NC(=O)N1CCN(c2ccccc2Cl)CC1 -US20060004084A1,5,CC1OC(=O)c2ccc(C=O)cc21.OCCO>>CC1OC(=O)c2ccc(C3OCCO3)cc21 -US20020107253A1,1,Cc1ccccc1N1CCNCC1.O=CCCCC1CC(c2ccccc2)=NO1>>Cc1ccccc1N1CCN(CCCCC2CC(c3ccccc3)=NO2)CC1 -US20130005760A1,6,Cc1noc(C)c1-c1ccc2c(=O)cc(C)n(-c3cc(NC(=O)OC(C)(C)C)c(F)cc3F)c2c1>>Cc1noc(C)c1-c1ccc2c(=O)cc(C)n(-c3cc(N)c(F)cc3F)c2c1 -US20070010520A1,1,C#CNC.Cc1ccc(Cl)c(C=O)c1F>>C#CN(C)Cc1c(Cl)ccc(C)c1F -US20080027070A1,2,Nc1cnc(Nc2ccc(C(=O)NCCN3CCCC3)nc2)nc1.O=C(Nc1ccc(Cl)c(C(=O)O)c1)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c(C(=O)Nc2cnc(Nc3ccc(C(=O)NCCN4CCCC4)nc3)nc2)c1)c1cccc(C(F)(F)F)c1 -US20090023746A1,1,CC(C)=O.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CN3CCCNCC3)c2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CN3CCCN(C(C)C)CC3)c2c1 -US08501746B2,2,Cc1nc(-n2ccc(OCc3ccc(F)cc3)cc2=O)sc1C(=O)O.NCc1cccnc1>>Cc1nc(-n2ccc(OCc3ccc(F)cc3)cc2=O)sc1C(=O)NCc1cccnc1 -US20050043331A1,1,C=O.COC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)c(N2CCNCC2)n1C>>COC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)c(N2CCN(C)CC2)n1C -US08501382B1,2,CC(C)(O)CCO.O=S(=O)(Cl)c1c(F)c(F)c(F)c(F)c1F>>CC(C)(O)CCOS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F -US20140113898A1,1,CC(C)(CCOS(C)(=O)=O)S(=O)(=O)c1cccc(C(F)(F)F)c1.[N-]=[N+]=[N-]>>CC(C)(CCN=[N+]=[N-])S(=O)(=O)c1cccc(C(F)(F)F)c1 -US20140315949A1,6,COC(=O)c1ccc(C(C)C(C)C)cc1>>CC(C)C(C)c1ccc(C(=O)O)cc1 -US20110112120A9,1,CC(C)COc1ccc(B(O)O)cc1.CCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(C)n(-c2ccc(OCC(C)C)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US08853193B2,1,O=[N+]([O-])c1cccnc1F.OCC1CC1(F)F>>O=[N+]([O-])c1cccnc1OCC1CC1(F)F -US08273738B2,2,CC(=O)c1cccc(O)c1.O=C(Cl)c1ccccc1>>CC(=O)c1cccc(OC(=O)c2ccccc2)c1 -US09024044B2,1,BrCc1ccccc1.CCC(Cc1ccc(C(=O)OC(C)(C)C)s1)C(=O)O>>CCC(Cc1ccc(C(=O)OC(C)(C)C)s1)C(=O)OCc1ccccc1 -US20090229352A1,6,CCOC(=O)C[C@H](NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1)c1ccccc1>>O=C(O)C[C@H](NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1)c1ccccc1 -US04992459,6,COc1cc(Cl)c(Cn2ccnc2S)c(Cl)c1>>Oc1cc(Cl)c(Cn2ccnc2S)c(Cl)c1 -US07425554B2,7,CCCCN1CCN(c2cc(C(=O)OC)ccc2C2CCC(C(C)(C)C)CC2)CC1>>CCCCN1CCN(c2cc(CO)ccc2C2CCC(C(C)(C)C)CC2)CC1 -US05298647,2,CSCC[C@H](N)C(=O)O.Nc1ccc(C(=O)O)cc1>>CSCC[C@H](NC(=O)c1ccc(N)cc1)C(=O)O -US04612316,6,O=C(Nc1ccccc1)Oc1cccc2c1CC[C@H]1[C@H]2CCCN1Cc1ccccc1>>O=C(Nc1ccccc1)Oc1cccc2c1CC[C@@H]1NCCC[C@@H]21 -US20100168164A1,3,CN(C)C=O.COc1ccc(C(OC)(OC)c2ccc(F)cc2)cc1>>COc1ccc(C(OC)(OC)c2ccc(F)c(C=O)c2)cc1 -US20100041657A1,6,COc1cc(C(C)(C)C)c(O)c(C(=O)Nc2ccc(S(=O)(=O)C(F)(F)F)cc2Cl)c1C>>Cc1c(O)cc(C(C)(C)C)c(O)c1C(=O)Nc1ccc(S(=O)(=O)C(F)(F)F)cc1Cl -US20130030012A1,1,CN1CCCn2c1cc(Cl)nc2=O.OCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>CN1CCCn2c1cc(OCCc1ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc1)nc2=O -US06350892B1,6,COC(=O)COc1ccc(CCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1>>CC(C)(C)[Si](OCCCc1ccc(OCC(=O)O)cc1)(c1ccccc1)c1ccccc1 -US20090105225A1,1,CS(=O)(=O)OCCCCc1ccc(OCCCN2CCCCCC2)cc1.O=c1c2ccccc2c(Cl)nn1C[C@H]1CCCN1>>O=c1c2ccccc2c(Cl)nn1C[C@H]1CCCN1CCCCc1ccc(OCCCN2CCCCCC2)cc1 -US06420376B1,6,CCOC(=O)C1CC2(CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(C(=O)O)c1ccccc12 -US20150183802A1,9,Cc1n[nH]c2cc(F)c(Br)cc12.[C-]#N>>Cc1n[nH]c2cc(F)c(C#N)cc12 -US20140018368A1,7,COC(=O)c1cc(OC)cc(C(=O)OC)c1>>COC(=O)c1cc(CO)cc(OC)c1 -US20060058366A1,7,O=[N+]([O-])c1ccc2[nH]nc(/C=C/c3cccnc3)c2c1>>Nc1ccc2[nH]nc(/C=C/c3cccnc3)c2c1 -US04741760,9,Cc1c(Cl)nc(Cl)nc1Cl.N>>Cc1c(N)nc(Cl)nc1Cl -US04954501,6,CCOC(=O)C1CCN(c2ccc(C3=NNC(=O)CC3C)cc2[N+](=O)[O-])CC1>>CC1CC(=O)NN=C1c1ccc(N2CCC(C(=O)O)CC2)c([N+](=O)[O-])c1 -US07173023B2,2,COC(=O)Cl.Fc1cccc(COc2ccc3c(c2)CCNCC3)c1>>COC(=O)N1CCc2ccc(OCc3cccc(F)c3)cc2CC1 -US20150087639A1,7,N#Cc1cccc(OCn2ccc3ccc([N+](=O)[O-])cc32)c1>>N#Cc1cccc(OCn2ccc3ccc(N)cc32)c1 -US08455477B2,6,Cn1cc(-c2cc(OCc3ccccc3)c3ccnn3c2)cn1>>Cn1cc(-c2cc(O)c3ccnn3c2)cn1 -US20120168732A1,2,COC(=O)c1cc(I)cc(I)c1.NN>>NNC(=O)c1cc(I)cc(I)c1 -US08637508B2,2,CC[Si](CC)(CC)c1cc(Br)nc([C@@](N)(CO)C(F)F)c1F.O=C(Cl)CCl>>CC[Si](CC)(CC)c1cc(Br)nc([C@](CO)(NC(=O)CCl)C(F)F)c1F -US20040242659A1,2,CC(C)(C)Oc1ccc(CCCCn2ccnc2CCO)cc1.CS(=O)(=O)Cl>>CC(C)(C)Oc1ccc(CCCCn2ccnc2CCOS(C)(=O)=O)cc1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](c2ccccc2)NC1=O.O=C(O)[C@@H]1C[C@H]1c1ccc(Cl)cc1>>CC(C)C[C@H]1C(=O)N[C@@H](c2ccccc2)CN1C(=O)[C@@H]1C[C@H]1c1ccc(Cl)cc1 -US20150158837A1,2,CNOC.COC(=O)CCc1ccccc1>>CON(C)C(=O)CCc1ccccc1 -US20110207739A1,2,Nc1ccc2c(c1N)C(=O)c1ccccc1C2=O.O=C(Cl)CCl>>Nc1c(NC(=O)CCl)ccc2c1C(=O)c1ccccc1C2=O -US06284755B1,1,CCC1(c2cccc(OCc3ccccc3)c2)CCCCN(CCO)C1=O.CI>>CCC1(c2cccc(OCc3ccccc3)c2)CCCCN(CCOC)C1=O -US20110071194A1,1,CC(C)n1ncc2cc(I)ccc21.C[C@H](N)[C@H](O)c1ccccc1>>CC(C)n1ncc2cc(O[C@H](c3ccccc3)[C@H](C)N)ccc21 -US06369273B1,1,Nc1cc(Cl)ccc1[N+](=O)[O-].Sc1ccc(Br)cc1>>Nc1cc(Sc2ccc(Br)cc2)ccc1[N+](=O)[O-] -US05187055,2,CCCCCCCCCCCCO.O=C(Cl)c1ccccc1[N+](=O)[O-]>>CCCCCCCCCCCCOC(=O)c1ccccc1[N+](=O)[O-] -US20110110889A1,2,CCCNS(=O)(=O)Nc1ccc(F)c(C(=O)O)c1F.Nc1cnc2[nH]ccc2c1>>CCCNS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]ccc3c2)c1F -US06884821B1,6,CCOC(=O)/C(=C/c1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)OC(C)C>>COc1ccc(/C=C(\OC(C)C)C(=O)O)cc1C(=O)NCc1ccc(C(F)(F)F)cc1 -US07314937B2,2,O=S(=O)(Cl)c1ccc(F)cc1.c1cc2c(cc1OCCCN1CCCCC1)CNCC2>>O=S(=O)(c1ccc(F)cc1)N1CCc2ccc(OCCCN3CCCCC3)cc2C1 -US20030092712A1,7,CC(C)(C)N1CC=C(c2cc(-c3ccc(F)cc3)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1>>CC(C)(C)N1CCC(c2cc(-c3ccc(F)cc3)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1 -US20040176361A1,1,CN1CCN(CCCCN2CCNCC2)CC1.Cc1cccc2c(=O)[nH]c(Cl)cc12>>Cc1cccc2c(=O)[nH]c(N3CCN(CCCCN4CCN(C)CC4)CC3)cc12 -US20110152260A1,2,CC(C)(C)[Si](C)(C)OC1CCC(n2c(Nc3nn(COCC[Si](C)(C)C)c4ccc(Br)cc34)nc3cc(C(=O)O)ccc32)CC1.NC1CCCC1>>CC(C)(C)[Si](C)(C)OC1CCC(n2c(Nc3nn(COCC[Si](C)(C)C)c4ccc(Br)cc34)nc3cc(C(=O)NC4CCCC4)ccc32)CC1 -US20030220348A1,1,COc1cnc(Cn2ccnc2-c2ncccn2)c(Cl)n1.C[O-]>>COc1cnc(Cn2ccnc2-c2ncccn2)c(OC)n1 -US20070293504A1,7,Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1[N+](=O)[O-]>>Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1N -US20130274469A1,2,C1COCCN1.Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)N2CCOCC2)cn1 -US04963568,6,COC(=O)[C@@H]1CCc2cc(OC)c(OC)c3c2[C@@H]1C[C@H](c1ccccc1)C3>>COc1cc2c3c(c1OC)C[C@@H](c1ccccc1)C[C@@H]3[C@H](C(=O)O)CC2 -US20120309766A1,2,COc1cc(OC)c(F)c(-c2ccc(C(=O)O)c3nccnc23)c1F.Nc1cccnc1>>COc1cc(OC)c(F)c(-c2ccc(C(=O)Nc3cccnc3)c3nccnc23)c1F -US20030187020A1,6,CCn1cc(C(=O)OC)c2ccccc21>>CCn1cc(C(=O)O)c2ccccc21 -US04408055,1,CC(=O)OCC(=O)Cl.CCOCCONC(C)C>>CCOCCON(C(=O)COC(C)=O)C(C)C -US20140107100A1,6,CC(C)(C)OC(=O)Nc1ncc(Br)cc1NS(C)(=O)=O>>CS(=O)(=O)Nc1cc(Br)cnc1N -US20100279990A1,1,CI.CN(C(=O)OC(C)(C)C)[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(C#CCCCO)cc21>>COCCCC#Cc1ccc2c(c1)[C@@H](N(C)C(=O)OC(C)(C)C)CC[C@H]2c1ccc(Cl)c(Cl)c1 -US20070049632A1,1,CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccc(F)cc3Cl)c(=O)c12.Fc1ccc(CBr)c(F)c1>>CC1(C)[C@@H]2CC[C@@]1(C)c1c2c(=O)n(-c2ccc(F)cc2Cl)n1Cc1ccc(F)cc1F -US20080293782A1,3,C=CCCCBr.CC(C)=O>>C=CCCCC(C)(C)O -US06187821B1,6,CCC(CCc1ccc(OCc2ccccc2)cc1)(COC(C)=O)NC(=O)OC(C)(C)C>>CCC(CCc1ccc(O)cc1)(COC(C)=O)NC(=O)OC(C)(C)C -US20060063779A1,2,Cc1ccsc1C(=O)O.Nc1ccc(Cl)c(-c2ccccn2)c1>>Cc1ccsc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1 -US20060155136A1,1,C[C@@H](O)[C@@](O)(CCl)c1ccc(F)cc1F>>C[C@@H](O)[C@]1(c2ccc(F)cc2F)CO1 -US04591458,1,CC(C)(C)OC(=O)CN1C(=O)[C@@H](N)COc2ccccc21.CCOC(=O)C(=O)CCCCCCC1CCN(C(=O)OCc2ccccc2)CC1>>CCOC(=O)[C@@H](CCCCCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@H]1COc2ccccc2N(CC(=O)OC(C)(C)C)C1=O -US07378417B2,2,CC(C)(CO)NS(=O)(=O)c1cccc(N)c1.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)cc3)nc12>>CC(C)(CO)NS(=O)(=O)c1cccc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(Cl)cc4)nc23)c1 -US04552585,2,CC1(C)CON(Cc2ccc(N)cc2Cl)C1=O.O=C(O)C1CC1>>CC1(C)CON(Cc2ccc(NC(=O)C3CC3)cc2Cl)C1=O -US07678818B2,3,CN(C)C=O.COC1(c2ccc(Br)cc2)CC1>>COC1(c2ccc(C=O)cc2)CC1 -US04508727,6,CC(C)C[C@H](N[C@@H](C)C(=O)N1C(=O)N(Cc2ccccc2)C[C@H]1C(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CC(C)C[C@H](N[C@@H](C)C(=O)N1C(=O)N(Cc2ccccc2)C[C@H]1C(=O)O)C(=O)OCc1ccccc1 -US20080090813A1,2,CN.O=S(=O)(Cl)c1cc(Br)cc(C(F)(F)F)c1>>CNS(=O)(=O)c1cc(Br)cc(C(F)(F)F)c1 -US20040138223A1,2,CCn1cc(CNc2ccc(C(C)C)cc2)cn1.O=C(O)C1CCCc2ccc(OCc3ccccc3)cc21>>CCn1cc(CN(C(=O)C2CCCc3ccc(OCc4ccccc4)cc32)c2ccc(C(C)C)cc2)cn1 -US20110136801A1,1,CCCCc1nc2c(N)nc3ccccc3c2n1CCCN.COC(=O)COc1cccc(C=O)c1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCNCc1cccc(OCC(=O)OC)c1 -US20070010526A1,1,C1COCCN1.COc1ccc(N2CCN(C)CC2)c2c1CCN(C(=O)Cc1cccc(Br)c1)C2>>COc1ccc(N2CCN(C)CC2)c2c1CCN(C(=O)Cc1cccc(N3CCOCC3)c1)C2 -US08921372B2,2,CC1(C)C[C@@H]1C(=O)O.COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3cc(Cl)c(NC(=O)c4ccc(N5CCNC[C@H]5C)nc4)cc3C(F)(F)F)cc2)c[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3cc(Cl)c(NC(=O)c4ccc(N5CCN(C(=O)[C@H]6CC6(C)C)C[C@H]5C)nc4)cc3C(F)(F)F)cc2)c[nH]1)C(C)C -US20110124642A1,2,Cc1ccc(-c2nn(N)c(=O)c3ccccc23)c(C)c1.O=C(O)C[C@@H]1C[C@@H]2C=C[C@H]1C2>>Cc1ccc(-c2nn(NC(=O)C[C@@H]3C[C@@H]4C=C[C@H]3C4)c(=O)c3ccccc23)c(C)c1 -US08211919B2,3,CC1(C)OB(c2ccncc2)OC1(C)C.O=C(Cc1ccccc1)N1CCc2cc(Br)ccc21>>O=C(Cc1ccccc1)N1CCc2cc(-c3ccncc3)ccc21 -US20150238601A1,1,O=C(CCl)NC1CC1.Oc1cc(Br)ccc1F>>O=C(COc1cc(Br)ccc1F)NC1CC1 -US20100034827A1,10,Cc1cc(C)cc(Oc2nc(Cl)nc(Cl)c2C(C)C)c1.O=C1CCC(=O)N1Br>>Cc1cc(CBr)cc(Oc2nc(Cl)nc(Cl)c2C(C)C)c1 -US08034812B2,2,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.Cc1nc(C)c(C(=O)O)s1>>Cc1nc(C)c(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2C)s1 -US20090054440A1,6,COC(=O)COc1c(-c2ccccc2)nc2ccccc2c1C(=O)NN(C(=O)OC)c1ccccc1>>COC(=O)N(NC(=O)c1c(OCC(=O)O)c(-c2ccccc2)nc2ccccc12)c1ccccc1 -US20060122234A1,2,COC(=O)c1ccc(-c2cccc(NCCc3ccccc3)n2)s1.NO>>O=C(NO)c1ccc(-c2cccc(NCCc3ccccc3)n2)s1 -US20110082181A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(=O)CCCc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(=O)CCCc4ccccc4)cc3)cc2)CC1 -US20060069087A1,1,C1CCNC1.COC(=O)c1ccc2[nH]c(C=O)cc2c1>>COC(=O)c1ccc2[nH]c(CN3CCCC3)cc2c1 -US06172228B2,1,Clc1cccc(C(c2ccccc2)N2CCNCC2)c1.O=S(=O)(CCCCCCBr)NC1CC1>>O=S(=O)(CCCCCCN1CCN(C(c2ccccc2)c2cccc(Cl)c2)CC1)NC1CC1 -US20110263591A1,2,C1CCNCC1.O=C(O)c1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)oc23)c1>>O=C(N[C@H]1CN2CCC1CC2)c1cc2cccc(-c3cccc(C(=O)N4CCCCC4)c3)c2o1 -US20150266837A1,6,CCN(NC(=O)OC(C)(C)C)c1ncn[nH]1>>CCN(N)c1ncn[nH]1 -US08669255B2,6,CC(C)(C)OC(=O)NC(C(=O)N1CCN2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2C1)c1ccc(C(F)(F)F)cc1>>NC(C(=O)N1CCN2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2C1)c1ccc(C(F)(F)F)cc1 -US08436186B2,1,CC(C)(C)OC(=O)NCC=O.CC1(C)CCC(C)(C)c2cc(-c3csc(C4CCNCC4)n3)ccc21>>CC(C)(C)OC(=O)NCCN1CCC(c2nc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)cs2)CC1 -US07803822B2,2,CCCN.[N-]=[N+]=Nc1ccc(C(=O)O)cc1>>CCCNC(=O)c1ccc(N=[N+]=[N-])cc1 -US05821246,1,COc1cc2c(Cl)ncnc2cc1OC(C)=O.Cc1cc(N)ccc1OCc1ccccn1>>COc1cc2c(Nc3ccc(OCc4ccccn4)c(C)c3)ncnc2cc1OC(C)=O -US20120214788A1,2,COC(=O)C1CNCC(c2cccc(C(F)(F)F)c2)C1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COC(=O)C1CC(c2cccc(C(F)(F)F)c2)CN(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1 -US07375099B2,2,CC(C(=O)O)C(=O)NCc1ccc(F)cc1.CN1C(=O)C(N)N=C(c2ccccc2)c2ccccc21>>CC(C(=O)NCc1ccc(F)cc1)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O -US09096639B2,2,CC(C)(C)CC(=O)Cl.CC(O)c1ccc([C@H]2C[C@@]3(C)[C@@H](CC[C@@]3(O)C(F)(F)C(F)(F)F)[C@@H]3CCC4=CC(=O)CCC4=C23)cc1>>CC(OC(=O)CC(C)(C)C)c1ccc([C@H]2C[C@@]3(C)[C@@H](CC[C@@]3(O)C(F)(F)C(F)(F)F)[C@@H]3CCC4=CC(=O)CCC4=C23)cc1 -US07429579B2,2,CC(C)(C)OC(=O)N1CCc2ccc(O)cc2CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCc2ccc(OS(C)(=O)=O)cc2CC1 -US04495100,1,CC(=O)Nc1ccc(S(=O)O)c2cccnc12.CC(=O)Oc1cccc(CBr)c1>>CC(=O)Nc1ccc(S(=O)(=O)Cc2cccc(OC(C)=O)c2)c2cccnc12 -US20150079035A1,7,CCOC(=O)c1ccc(NC2CCCCCC2)c([N+](=O)[O-])c1>>CCOC(=O)c1ccc(NC2CCCCCC2)c(N)c1 -US08481539B2,3,C[Si](C)(C)C#Cc1cc(N)ccc1F.Cn1ncc2c(Br)cncc21>>Cn1ncc2c(C#Cc3cc(N)ccc3F)cncc21 -US05286869,2,COC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc([N+](=O)[O-])c1.OC/C=C/C#Cc1ccc(Cc2ncc[nH]2)cc1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC/C=C/C#Cc2ccc(Cc3ncc[nH]3)cc2)C1c1cccc([N+](=O)[O-])c1 -US20100125081A1,3,NC1=NC(c2cccc(Br)c2)(c2ccnc(C(F)(F)F)c2)c2cccnc21.OB(O)c1cncnc1>>NC1=NC(c2cccc(-c3cncnc3)c2)(c2ccnc(C(F)(F)F)c2)c2cccnc21 -US20090247507A1,1,Nc1ncc(Br)c(Cl)c1[N+](=O)[O-].c1cncc(CN2CCNCC2)c1>>Nc1ncc(Br)c(N2CCN(Cc3cccnc3)CC2)c1[N+](=O)[O-] -US20070049618A1,2,NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccccn1>>O=C1CCC(N2Cc3c(CNC(=O)c4ccccn4)cccc3C2=O)C(=O)N1 -US20110212943A1,2,CC(=O)NC12CC3CC(C1)CC(C(=O)O)(C3)C2.NCc1ccc(C(=O)Nc2ccccc2N)cc1>>CC(=O)NC12CC3CC(C1)CC(C(=O)NCc1ccc(C(=O)Nc4ccccc4N)cc1)(C3)C2 -US06864265B2,6,CC(C)(C)OC(=O)N(Cc1ccc(CNC2(C)CCCc3cccnc32)cc1)Cc1ccccn1>>CC1(NCc2ccc(CNCc3ccccn3)cc2)CCCc2cccnc21 -US20140135327A1,6,C=C1CN(Cc2ccc(C(=O)Nc3ccccc3N)cc2)C(CC(=O)OC)c2ccccc21>>C=C1CN(Cc2ccc(C(=O)Nc3ccccc3N)cc2)C(CC(=O)O)c2ccccc21 -US06407094B1,7,COCCOc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1-c1ccc(F)cc1>>COCCOc1cc(NC(=O)OC(C)(C)C)c(N)cc1-c1ccc(F)cc1 -US05869485,2,NCCO.Nc1ncnc2c1c(-c1ccccc1)cn2-c1cccc(C(=O)O)c1>>Nc1ncnc2c1c(-c1ccccc1)cn2-c1cccc(C(=O)NCCO)c1 -US20150252038A1,1,COC(=O)c1cc(C2CC2)c(OCC2CCNCC2)cc1F.Cn1nc(C(F)(F)F)c(C=O)c1Cl>>COC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3c(C(F)(F)F)nn(C)c3Cl)CC2)cc1F -US20140309192A1,2,CCN(CC)c1ccc(C(=O)O)cc1.Nc1ccc(Cl)cc1N1CCN(CCC(F)(F)F)CC1>>CCN(CC)c1ccc(C(=O)Nc2ccc(Cl)cc2N2CCN(CCC(F)(F)F)CC2)cc1 -US03985804,2,COc1cccc(N)c1.Cc1ccccc1C(=O)Cl>>COc1cccc(NC(=O)c2ccccc2C)c1 -US06169091A,1,O=c1[nH]cnc2cnc(Cl)cc12.OCc1ccccc1>>O=c1[nH]cnc2cnc(OCc3ccccc3)cc12 -US06888032B2,9,Cc1cc(C)cc(Br)c1.[C-]#N>>Cc1cc(C)cc(C#N)c1 -US20060183762A1,2,CC(C)(C)OC(=O)NN.O=C(O)c1cc(F)c(F)cc1NC1CC1>>CC(C)(C)OC(=O)NNC(=O)c1cc(F)c(F)cc1NC1CC1 -US06965048B2,2,CCOC(=O)CCNC.CN(CC[C@@H]1CC[C@@H](C(=O)O)CC1)C(=O)Oc1ccc(Cl)cc1>>CCOC(=O)CCN(C)C(=O)[C@@H]1CC[C@@H](CCN(C)C(=O)Oc2ccc(Cl)cc2)CC1 -US20150080549A1,1,CSSC(CN=[N+]=[N-])C[C@H](NC(=O)OC(C)(C)C)C(=O)O.N#CCBr>>CSSC(CN=[N+]=[N-])C[C@H](NC(=O)OC(C)(C)C)C(=O)OCC#N -US20140135318A1,1,BrCCCc1ccccc1.CCCCN(CCCC)C(=O)c1c[nH]c(-c2ccc(C(=O)OC)cc2C(=O)OCc2ccccc2)n1>>CCCCN(CCCC)C(=O)c1cn(CCCc2ccccc2)c(-c2ccc(C(=O)OC)cc2C(=O)OCc2ccccc2)n1 -US20080188484A1,1,CC(C)N1CCC(O)CC1.CCOC(=O)c1cc2cc(O)c(Br)cc2[nH]1>>CCOC(=O)c1cc2cc(OC3CCN(C(C)C)CC3)c(Br)cc2[nH]1 -US20150099734A1,2,O=C(OCc1cc(Cl)cc(Cl)c1)N1CCC2(CC1)CNC2.O=c1[nH]c2ccc(S(=O)(=O)Cl)cc2o1>>O=C(OCc1cc(Cl)cc(Cl)c1)N1CCC2(CC1)CN(S(=O)(=O)c1ccc3[nH]c(=O)oc3c1)C2 -US20120245171A1,7,O=[N+]([O-])c1cc(Br)cc2nn(C3CCCCO3)cc12>>Nc1cc(Br)cc2nn(C3CCCCO3)cc12 -US20090182144A1,7,CCn1c(C(C)=O)cnc1Oc1ccc(C)cc1>>CCn1c(C(C)O)cnc1Oc1ccc(C)cc1 -US20090318504A1,1,Cc1ccc(Nc2cc(N3CCCCC3)nc(N3CCNCC3)n2)cc1.Cc1cccnc1Br>>Cc1ccc(Nc2cc(N3CCCCC3)nc(N3CCN(c4ncccc4C)CC3)n2)cc1 -US20120028919A1,3,COCCN1CCc2ccc(Nc3ncc4ccc(Br)n4n3)cc2CC1.OB(O)c1ccccc1>>COCCN1CCc2ccc(Nc3ncc4ccc(-c5ccccc5)n4n3)cc2CC1 -US20080312208A1,1,CC(C)(C)OC(=O)C1CNC1.CCOC(=O)c1cnc(Cl)c(Cl)c1N>>CCOC(=O)c1cnc(N2CC(C(=O)OC(C)(C)C)C2)c(Cl)c1N -US20110124665A1,1,CCOC(=O)/C=C/c1cccc(N)c1.COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1>>CCOC(=O)/C=C/c1cccc(Nc2ncnc3oc(-c4ccccc4)c(-c4ccc(OC)cc4)c23)c1 -US20070299068A1,3,CCn1ccc2ccc(C(=O)OC)cc21.CN(C)C=O>>CCn1cc(C=O)c2ccc(C(=O)OC)cc21 -US20130289071A1,2,CC1=C(c2ccc(N)cc2)CN(c2nnn(C)n2)CC1.Cc1ncccc1C(=O)O>>CC1=C(c2ccc(NC(=O)c3cccnc3C)cc2)CN(c2nnn(C)n2)CC1 -US05268355,3,C#CCO.CC(=O)CCC1=C(C)CCCC1(C)C>>CC1=C(CCC(C)(O)C#CCO)C(C)(C)CCC1 -US20140309226A1,6,CC(C)(C)OC(=O)N[C@H]1CCN(C(=O)c2ccc(CN3CCN(C4CCN(c5ncc(C(F)(F)F)cc5F)CC4)C3=O)cc2)C1>>N[C@H]1CCN(C(=O)c2ccc(CN3CCN(C4CCN(c5ncc(C(F)(F)F)cc5F)CC4)C3=O)cc2)C1 -US20140309226A1,6,CC(C)(C)OC(=O)N[C@H]1CCN(C(=O)c2ccc(CN3CCN(C4CCN(c5ncc(C(F)(F)F)cc5F)CC4)C3=O)cc2)C1>>N[C@H]1CCN(C(=O)c2ccc(CN3CCN(C4CCN(c5ncc(C(F)(F)F)cc5F)CC4)C3=O)cc2)C1 -US04251659,6,OC(c1ccc2c(c1)CCN2C(c1ccccc1)c1ccccc1)(C(F)(F)Cl)C(F)(F)Cl>>OC(c1ccc2c(c1)CCN2)(C(F)(F)Cl)C(F)(F)Cl -US20150141669A1,1,C=CCOC(=O)N1COC(=O)[C@@]12[C@@H](F)C[C@H]1[C@H](C(=O)O)[C@H]12.O=C1OC(Br)c2ccccc21>>C=CCOC(=O)N1COC(=O)[C@]12C1[C@@H](C(=O)O[C@H]3OC(=O)c4ccccc43)[C@@H]1C[C@@H]2F -US05849911,2,CC[C@H](C)[C@H](NC(=O)OC)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(N)Cc1ccc(-c2nccs2)cc1.COC(=O)N[C@H](C(=O)O)C(C)C>>CC[C@H](C)[C@H](NC(=O)OC)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(-c2nccs2)cc1)NC(=O)[C@@H](NC(=O)OC)C(C)C -US20070173486A1,2,FC(F)(F)c1ccccc1C(OC1CNC1)c1ccc(Cl)cc1.S=C=NCC1CCCO1>>FC(F)(F)c1ccccc1C(OC1CN(C(=S)NCC2CCCO2)C1)c1ccc(Cl)cc1 -US20120323040A1,6,CCOC(=O)CCCc1cccc(F)c1>>O=C(O)CCCc1cccc(F)c1 -US20130281490A1,2,Cc1ccc(CCOC(=O)N[C@@H](C(=O)O)[C@H](C)O)cc1>>Cc1ccc(CCOC(=O)N[C@H]2C(=O)O[C@H]2C)cc1 -US20090137609A1,6,CCC(O)(CC)CCc1ccc(C(CC)(CC)c2ccc(-c3cncc(CC(=O)OC)c3)c(C)c2)cc1C>>CCC(O)(CC)CCc1ccc(C(CC)(CC)c2ccc(-c3cncc(CC(=O)O)c3)c(C)c2)cc1C -US20110230497A1,3,CS(=O)(=O)N1CCC(CC(=O)Nc2ccc(Br)nc2)CC1.OB(O)c1cc(F)cc(F)c1>>CS(=O)(=O)N1CCC(CC(=O)Nc2ccc(-c3cc(F)cc(F)c3)nc2)CC1 -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.NC(=O)c1nn(-c2ccnc(Br)c2)c2c1CCCC2>>CN1CC[C@@](O)(C#Cc2cc(-n3nc(C(N)=O)c4c3CCCC4)ccn2)C1=O -US06407094B1,2,CCOC(=O)CC(=O)c1cccc(-n2cnnc2)c1.COc1cc(NC(=O)OC(C)(C)C)c(N)cc1-c1ccccc1F>>COc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3cnnc3)c2)cc1-c1ccccc1F -US06048880,10,Cc1cc(Cl)sc1Cl.O=C1CCC(=O)N1Br>>Clc1cc(CBr)c(Cl)s1 -US20090054435A1,3,Brc1ccc(OCc2ccccc2)cc1.COCOc1cc(OC)ccc1C(=O)N(C)OC>>COCOc1cc(OC)ccc1C(=O)c1ccc(OCc2ccccc2)cc1 -US20150238558A1,6,COC(=O)c1ccc(CN(C(=O)[C@@H]2Cc3ccccc3CN2C(=O)OCc2ccccc2)[C@H](C)c2ccccc2Cl)cc1>>COC(=O)c1ccc(CN(C(=O)[C@@H]2Cc3ccccc3CN2)[C@H](C)c2ccccc2Cl)cc1 -US20090227555A2,1,CCc1cnc(-c2cnc(Cl)c(Cl)c2SC)o1.COC(=O)C1CCNCC1>>CCc1cnc(-c2cnc(N3CCC(C(=O)OC)CC3)c(Cl)c2SC)o1 -US05627165,7,CCOC(=O)CC(=O)c1ccc(OC(C)=O)cc1>>CCOC(=O)CC(O)c1ccc(OC(C)=O)cc1 -US20040214868A1,7,COC(=O)c1ccc(NC(=O)c2cc(OCc3ccccc3C)cc(OC(C)=O)c2)nc1>>COC(=O)c1ccc(NC(=O)c2cc(O)cc(OCc3ccccc3C)c2)nc1 -US06727318B1,2,C=C(C)C(=O)Cl.O=C1c2ccc3c4cccc5cccc(c6ccc(c2c36)C(=O)N1CCCCCO)c54>>C=C(C)C(=O)OCCCCCN1C(=O)c2ccc3c4cccc5cccc(c6ccc(c2c36)C1=O)c54 -US20120178736A1,3,CCCC[Sn](CCCC)(CCCC)c1nc(N2CCOCC2)c2sc(CN3CCN(C(C)(C)C(N)=O)CC3)cc2n1.Cc1cn2c(Br)cccc2n1>>Cc1cn2c(-c3nc(N4CCOCC4)c4sc(CN5CCN(C(C)(C)C(N)=O)CC5)cc4n3)cccc2n1 -US20070213348A1,6,CC(C)(C)OC(=O)/C=C/c1ccc(C(=C2CCCCC2)c2ccc(O)c(F)c2)cc1>>O=C(O)/C=C/c1ccc(C(=C2CCCCC2)c2ccc(O)c(F)c2)cc1 -US20090176786A1,2,COc1ccc(CNC(=O)N(C)c2ccc(SC(F)(F)F)cc2F)cc1.O=C(Cl)c1c(F)cccc1F>>COc1ccc(CN(C(=O)c2c(F)cccc2F)C(=O)N(C)c2ccc(SC(F)(F)F)cc2F)cc1 -US05229386,6,COc1ccc(-c2nc(CNC(C)=O)sc2-c2ccc(OC)cc2)cc1>>COc1ccc(-c2nc(CN)sc2-c2ccc(OC)cc2)cc1 -US20070249670A1,6,CCOC(=O)CN(Cc1ccccn1)C(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cccc1C>>Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N(CC(=O)O)Cc1ccccn1 -US07528136B2,6,COC(=O)C1CC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1Cc1ccccc1>>O=C(O)C1CC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1Cc1ccccc1 -US20060252812A1,3,Brc1cccc2c1C1(COc3cc4c(cc31)CCO4)CN2Cc1ccccn1.OB(O)c1cncnc1>>c1ccc(CN2CC3(COc4cc5c(cc43)CCO5)c3c(-c4cncnc4)cccc32)nc1 -US06136810,9,CCn1c(=O)nc(-c2cccc(Cl)c2)c2ccc(C=O)nc21.NO>>CCn1c(=O)nc(-c2cccc(Cl)c2)c2ccc(C=NO)nc21 -US20110213149A1,7,NC(=CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F>>NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F -US20150175601A1,3,Clc1ncc2cccc(Br)c2n1.Nc1cccc(B(O)O)c1>>Nc1cccc(-c2cccc3cnc(Cl)nc23)c1 -US07713994B2,7,CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)nc2)CC1 -US20140107094A1,3,CON(C)C(=O)c1cncs1.Cn1cncc1Br>>Cn1cncc1C(=O)c1cncs1 -US20140275175A1,3,Brc1cncc(Br)c1.COc1c(B2OC(C)(C)C(C)(C)O2)ccc2c1CC(=O)N2C>>COc1c(-c2cncc(Br)c2)ccc2c1CC(=O)N2C -US20090005353A1,1,CC(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.NC1CN(c2ncc(C(F)(F)F)cc2Cl)C1>>CC(C)N1C(=O)C(NC2CN(c3ncc(C(F)(F)F)cc3Cl)C2)=C(c2ccccc2)S1(=O)=O -US08916560B2,1,CCC(C)N.COC(=O)c1ccc2nc(-c3ccccc3)c(Br)nc2c1>>CCC(C)Nc1nc2cc(C(=O)OC)ccc2nc1-c1ccccc1 -US20150284397A1,1,COc1cc(-c2cc3c(Cl)ncnc3n2S(=O)(=O)c2ccccc2)ccn1.Cc1ccc(-c2[nH]c(C3CCNCC3)nc2C(F)(F)F)cc1>>COc1cc(-c2cc3c(N4CCC(c5nc(C(F)(F)F)c(-c6ccc(C)cc6)[nH]5)CC4)ncnc3n2S(=O)(=O)c2ccccc2)ccn1 -US20130196998A1,1,CC(C)(C)OC(=O)C1CC(=O)C1.Clc1cccc(Cl)c1COc1ccc2c(c1)OCC21CCNCC1>>CC(C)(C)OC(=O)C1CC(N2CCC3(CC2)COc2cc(OCc4c(Cl)cccc4Cl)ccc23)C1 -US20120208819A1,6,CC(C)(C)OC(=O)NCc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1>>NCc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1 -US06528503B2,3,C=CC(C)(C)CC(=O)OC.ICI>>COC(=O)CC(C)(C)C1CC1 -US20090258904A1,6,CCOC(=O)[C@@H]1CC(c2ccc(C)cn2)=C(C)[C@H]1OC(C)=O>>CCOC(=O)[C@@H]1CC(c2ccc(C)cn2)=C(C)[C@H]1O -US20070161654A1,1,CCCc1ccc(B(O)O)cc1.Cc1onc(-c2ccccc2)c1-c1c[nH]cn1>>CCCc1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C)c2)cc1 -US20100331293A1,3,CCCC[Sn](CCCC)(CCCC)c1cc(C)ccn1.Cc1c(Cl)nc2c(Cl)cccc2c1Cl>>Cc1ccnc(-c2nc3c(Cl)cccc3c(Cl)c2C)c1 -US20030212095A1,1,Brc1nccs1.N#Cc1ccc(OCC(O)CN2CC3CNCC(C3)C2)cc1>>N#Cc1ccc(OCC(O)CN2CC3CC(C2)CN(c2nccs2)C3)cc1 -US04438141,1,ClCc1ccc(Cl)cc1.O=C1NC(=O)C(Cc2ccc(O)cc2)S1>>O=C1NC(=O)C(Cc2ccc(OCc3ccc(Cl)cc3)cc2)S1 -US20070142460A1,7,NC(=O)c1cc([N+](=O)[O-])ccc1Cl>>NC(=O)c1cc(N)ccc1Cl -US04490284,7,CC(C)(C=O)Cc1ccccc1>>CC(C)(CO)Cc1ccccc1 -US20080039476A1,2,CC1NCCC2=C1C(C)(C)C=C2.O=C(O)c1cc2ncc(Br)cn2n1>>CC1C2=C(C=CC2(C)C)CCN1C(=O)c1cc2ncc(Br)cn2n1 -US04163846,2,CC(=O)Cl.Cn1nc2nc(C(C)(C)C)[nH]c(=O)c2c1N>>CC(=O)Nc1c2c(=O)[nH]c(C(C)(C)C)nc2nn1C -US08163728B2,2,CC(C)N.Cc1onc(-c2ccc(F)cc2)c1CNc1cc(C(=O)O)n(C)n1>>Cc1onc(-c2ccc(F)cc2)c1CNc1cc(C(=O)NC(C)C)n(C)n1 -US06018046,1,CCCOC(=O)CBr.O=c1c(Cc2cccnc2)cn2c3ccc(Br)cc3c3cc(O)cc1c32>>CCCOC(=O)COc1cc2c(=O)c(Cc3cccnc3)cn3c4ccc(Br)cc4c(c1)c23 -US20140031544A1,2,Cc1nc2cc(C(=O)O)ccc2[nH]1.c1ccc2c(c1)C[C@@H]1NCCC[C@H]21>>Cc1nc2cc(C(=O)N3CCC[C@@H]4c5ccccc5C[C@@H]43)ccc2[nH]1 -US20050148624A1,2,CS(=O)(=O)c1ccc(Cn2c(C(=O)O)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1.OCc1ccncc1>>CS(=O)(=O)c1ccc(Cn2c(C(=O)OCc3ccncc3)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1 -US07632829B2,1,C1CCNCC1.CC(C)(CO)CBr>>CC(C)(CO)CN1CCCCC1 -US20060025445A1,2,CCOC(=O)C(C)N.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)C(C)NS(=O)(=O)c1ccccc1 -US20060264460A1,6,COc1cc([N+](=O)[O-])cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc12>>N#Cc1cnc2c(O)cc([N+](=O)[O-])cc2c1Nc1ccc(F)c(Cl)c1 -US07910595B2,2,Nc1ccccc1F.O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(Nc1ccccc1F)c1ccc(Cl)c([N+](=O)[O-])c1 -US20110319379A1,1,CCn1cc2c(O)cc(C(=O)OC)cc2n1.O=C(c1cnc(Cl)cn1)N1CCC1>>CCn1cc2c(Oc3cnc(C(=O)N4CCC4)cn3)cc(C(=O)OC)cc2n1 -US20150175594A1,1,CC(C)(C)OC(=O)Nc1sc2ccccc2c1C(=O)ON=C(N)C1CC1>>CC(C)(C)OC(=O)Nc1sc2ccccc2c1-c1nc(C2CC2)no1 -US06348474B1,2,CC(=O)O.COC(=O)c1ccc2nc(C)n(Cc3ccc(N)cc3Cl)c2n1>>COC(=O)c1ccc2nc(C)n(Cc3ccc(NC(C)=O)cc3Cl)c2n1 -US20060148858A1,2,CC(C)(C(=O)O)c1ccc(OCc2ccccc2)cc1.CCO>>CCOC(=O)C(C)(C)c1ccc(OCc2ccccc2)cc1 -US05026704,9,COC(=O)Cn1c(=O)c(=O)[nH]c2ccccc21.N>>NC(=O)Cn1c(=O)c(=O)[nH]c2ccccc21 -US05994356,1,CC1CN(C(=O)OC(C)(C)C)CCN1c1ccc(O)cc1.COC(=O)CBr>>COC(=O)COc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2C)cc1 -US08569535B2,6,CCOC(=O)C1(NC(=O)c2cccc(C#N)c2C)Cc2ccccc2C1>>Cc1c(C#N)cccc1C(=O)NC1(C(=O)O)Cc2ccccc2C1 -US05284841,4,N#Cc1ccccc1.[N-]=[N+]=[N-]>>c1ccc(-c2nnn[nH]2)cc1 -US09156840B2,6,CN(C)CCOC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(C(=O)OC(C)(C)C)CC3)C2=O)c1>>CN(C)CCOC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1 -US07723367B2,2,NCc1cccnc1Br.S=C=Nc1cccc(Cl)c1Cl>>S=C(NCc1cccnc1Br)Nc1cccc(Cl)c1Cl -US20050059723A1,1,Cc1cc2ccccc2[nH]1.Fc1cc(Br)ccc1OCc1ccccc1>>Cc1cc2ccccc2n1-c1ccc(OCc2ccccc2)c(F)c1 -US04363816,2,CCOC(=O)c1c(Nc2ccccc2N)cc(C)n1C>>Cc1cc2c(n1C)C(=O)Nc1ccccc1N2 -US20120264735A1,6,CCn1cc(-n2ccc(=O)c(C(C)c3cccc(-c4ncc(OCc5ccccc5)cn4)c3)n2)cn1>>CCn1cc(-n2ccc(=O)c(C(C)c3cccc(-c4ncc(O)cn4)c3)n2)cn1 -US20030220368A1,1,COc1ncc(Cl)cc1C=O.Fc1ccccc1/C=C/C1CCNCC1>>COc1ncc(Cl)cc1CN1CCC(/C=C/c2ccccc2F)CC1 -US08710224B2,1,CC(C)(C)OC(=O)N1CCNC[C@@H]1C(=O)N1CCN(Cc2ccccc2)CC1.O=C1CCC1>>CC(C)(C)OC(=O)N1CCN(C2CCC2)C[C@@H]1C(=O)N1CCN(Cc2ccccc2)CC1 -US20140162985A1,7,O=C1CCCc2cc3c(cnn3-c3ccc(F)cc3)cc2/C1=C\c1ccccn1>>O=C1CCCc2cc3c(cnn3-c3ccc(F)cc3)cc2C1Cc1ccccn1 -US20040067983A1,6,COc1ccc(-n2nc(COC3CCCCO3)cc2-c2ccc(Cl)c(Cl)c2)cc1>>COc1ccc(-n2nc(CO)cc2-c2ccc(Cl)c(Cl)c2)cc1 -US04453972,1,CSc1cc(Cl)c(O)cc1Cl.Cc1cc(F)cc(F)n1>>CSc1cc(Cl)c(Oc2cc(C)nc(F)c2)cc1Cl -US20080188487A1,6,CCOC(=O)c1cc2cc(C(=O)N3CCCN(C(=O)OC(C)(C)C)CC3)ccc2n1C(C)C>>CC(C)n1c(C(=O)O)cc2cc(C(=O)N3CCCN(C(=O)OC(C)(C)C)CC3)ccc21 -US20080027094A1,5,COCBr.Oc1cccc(I)c1>>COCOc1cccc(I)c1 -US20150266834A1,3,COc1nc(Cl)nc(Cl)n1.Cc1cc(B(O)O)ccc1Cl>>COc1nc(Cl)nc(-c2ccc(Cl)c(C)c2)n1 -US20150252032A1,2,C[C@@]1(C(=O)O)CCCN1.Cc1ccc(-n2nccn2)c(C(=O)Cl)c1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@]2(C)C(=O)O)c1 -US06451781B1,6,COC(=O)CCC(C)C1CCC2C3C(O)CC4CC(OCCN5C(=O)c6ccccc6C5=O)CCC4(C)C3CC(O)C12C>>COC(=O)CCC(C)C1CCC2C3C(O)CC4CC(OCCN)CCC4(C)C3CC(O)C12C -US07084165B2,9,O=Cc1cc(Br)ccc1Oc1ccc(Cl)c(Cl)c1.[C-]#N>>N#Cc1ccc(Oc2ccc(Cl)c(Cl)c2)c(C=O)c1 -US07968720B2,8,CCC(=O)NCc1ccc(Cl)c(CO)c1>>CCC(=O)NCc1ccc(Cl)c(C=O)c1 -US20020006932A1,1,Cc1ccccc1C1=CNC(=O)C12CCN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)CC2.ClCCN1CCCC1>>Cc1ccccc1C1=CN(CCN2CCCC2)C(=O)C12CCN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)CC2 -US05622825,1,NCCC(=O)O.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>O=C(O)CCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] -US05393788,2,COc1ccc(CCN)cc1OC1CCCC1.NC(=O)C(=O)O>>COc1ccc(CCNC(=O)C(N)=O)cc1OC1CCCC1 -US20110245221A1,7,CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1NCc1cc(C(=O)OC)no1>>CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1NCc1cc(CO)no1 -US20150252044A1,2,O=C(O)c1ccc2cncc(-c3ccc(Cl)cc3)c2n1.O=S1(=O)CCNCC1>>O=C(c1ccc2cncc(-c3ccc(Cl)cc3)c2n1)N1CCS(=O)(=O)CC1 -US06100252,3,COC(=O)c1cccc(I)c1.Cc1ccc(I)cc1>>COC(=O)c1cccc(-c2ccc(C)cc2)c1 -US06858625B1,1,CCNC1CNC1.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Br)c32)c(F)cc1F>>CCNC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4nc(N)c(F)cc4F)c3c2Br)C1 -US08927536B2,6,Cc1cnc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)nc1>>Cc1cnc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)nc1 -US06706878B2,3,Brc1cnc2c(c1)CC1(CN3CCC1CC3)O2.CCCC[Sn](CCCC)(CCCC)c1cccnc1>>c1cncc(-c2cnc3c(c2)CC2(CN4CCC2CC4)O3)c1 -US08299070B2,1,CC1(C)CCc2c(-c3cc4ccc(NC(=O)OCc5ccccc5)cc4n3COCC[Si](C)(C)C)nn(COCC[Si](C)(C)C)c2C1.CI>>CN(C(=O)OCc1ccccc1)c1ccc2cc(-c3nn(COCC[Si](C)(C)C)c4c3CCC(C)(C)C4)n(COCC[Si](C)(C)C)c2c1 -US06677336B2,1,COc1ccccc1OCC(O)CN1CCNCC1=O.Cc1cccc(C)c1NC(=O)CCl>>COc1ccccc1OCC(O)CN1CCN(CC(=O)Nc2c(C)cccc2C)CC1=O -US07649093B2,1,CCCc1cc2cc(OC)ccc2c(O)c1-c1ccccc1.O=Cc1ccc(F)cc1>>CCCc1cc2cc(OC)ccc2c(Oc2ccc(C=O)cc2)c1-c1ccccc1 -US08247403B2,6,CC(C)(C)OC(=O)N1CCOc2c(cccc2-c2cccs2)C1>>c1csc(-c2cccc3c2OCCNC3)c1 -US05585359,2,CCC(C)[C@H](N)CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12.O=C(Cl)COCc1ccccc1>>CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12)NC(=O)COCc1ccccc1 -US20040127465A1,7,O=Cc1cc(Cl)ccc1OCc1ccccc1>>OCc1cc(Cl)ccc1OCc1ccccc1 -US05811424,1,CC(C)(N)CO.N#Cc1ccc(Cl)cc1>>CC(C)(N)COc1ccc(C#N)cc1 -US20070219210A1,3,CC(C)(C)NC(=O)c1cc(-c2ccc(C=O)cn2)n(-c2cccnc2)n1.C[Mg+]>>CC(O)c1ccc(-c2cc(C(=O)NC(C)(C)C)nn2-c2cccnc2)nc1 -US04931083,2,CC(Oc1ncn(-c2cccc(Cl)c2)n1)C(=O)O.CN>>CNC(=O)C(C)Oc1ncn(-c2cccc(Cl)c2)n1 -US20110263571A1,3,CB(O)O.CC(C)(C)OC(=O)N1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1>>Cc1cc(C(F)(F)F)cnc1N1CCN(C(=O)OC(C)(C)C)CC1 -US20130338148A1,1,CC(=O)N1CCC(=O)CC1.NNC(=O)c1ccccc1>>CC(=O)N1CCC(=NNC(=O)c2ccccc2)CC1 -US05981525,2,CCNCC.CO/C(=C\C=C\c1cc2ccccc2[nH]1)C(=O)O>>CCN(CC)C(=O)/C(=C/C=C/c1cc2ccccc2[nH]1)OC -US20050283006A1,9,COC(=O)C1C(=O)C(C)[C@@H]2CCCN2C1=O>>CC1C(=O)CC(=O)N2CCC[C@@H]12 -US20020037891A1,1,CSCc1cccc(N2CCNCC2)c1.Cn1cc(C(=O)O)c(=O)c2cc3cc(F)c(F)cc3nc21>>CSCc1cccc(N2CCN(c3cc4nc5c(cc4cc3F)c(=O)c(C(=O)O)cn5C)CC2)c1 -US20150119362A1,1,CCc1cc(Cl)nc(C2CCCC2)n1.Nc1ccc(CCO)cc1>>CCc1cc(Nc2ccc(CCO)cc2)nc(C2CCCC2)n1 -US08492540B2,1,Cc1n[nH]c(=O)[nH]c1=O.ClCCCCBr>>Cc1nn(CCCCCl)c(=O)[nH]c1=O -US20050070562A1,1,CC(C)OC(=O)N1CCC(O)CC1.Cc1c(Cl)ccnc1Cl>>Cc1c(OC2CCN(C(=O)OC(C)C)CC2)ccnc1Cl -US20090270361A1,1,Cc1ccccc1O.Cc1nn(-c2ccc(C#N)cc2)c(C)c1CO>>Cc1ccccc1OCc1c(C)nn(-c2ccc(C#N)cc2)c1C -US06555552B2,1,N[C@@H]1CC[C@H]2CC[C@]1(c1ccccc1)N2.O=Cc1cc(-n2nnnc2C(F)(F)F)ccc1OC1CC1>>FC(F)(F)c1nnnn1-c1ccc(OC2CC2)c(CN[C@@H]2CC[C@H]3CC[C@]2(c2ccccc2)N3)c1 -US20060223875A1,7,COc1ccc(C2(C#N)CC2CO)cc1>>COc1ccc(C2(CN)CC2CO)cc1 -US20100273816A1,1,CC(C)S(=O)(=O)c1cccc(Br)c1.Oc1ccc(Cl)c(-c2ncnc3c(Cl)cccc23)c1>>CC(C)S(=O)(=O)c1cccc(Oc2ccc(Cl)c(-c3ncnc4c(Cl)cccc34)c2)c1 -US04072696,2,COC(=O)N=C=S.Nc1ccc(S(=O)c2ccccc2)cc1[N+](=O)[O-]>>COC(=O)NC(=S)Nc1ccc(S(=O)c2ccccc2)cc1[N+](=O)[O-] -US20110009454A1,1,N#Cc1ccc(F)cc1.Oc1cccc(F)c1>>N#Cc1ccc(Oc2cccc(F)c2)cc1 -US20080064720A1,1,BrCc1ccccc1.Oc1ccc2nc(Cl)ccc2c1>>Clc1ccc2cc(OCc3ccccc3)ccc2n1 -US04115348,1,O=C(c1ccccc1)c1ccc(OCCBr)cc1O.Oc1ccc(-c2nc3ccccc3s2)cc1>>O=C(c1ccccc1)c1ccc(OCCOc2ccc(-c3nc4ccccc4s3)cc2)cc1O -US20090124598A1,2,CNCc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1.CS(=O)(=O)Cl>>CN(Cc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1)S(C)(=O)=O -US06384051B1,1,C1COCCN1.COc1cc2c(Nc3cc(O)c(Cl)cc3F)c(C#N)cnc2cc1OCCCCl>>COc1cc2c(Nc3cc(O)c(Cl)cc3F)c(C#N)cnc2cc1OCCCN1CCOCC1 -US08138189B2,1,CC(c1cc(O)ccc1Cl)C(O)(c1ccnc(Cl)c1)C(F)(F)F.COC(=O)c1cnc(Cl)cn1>>COC(=O)c1cnc(Oc2ccc(Cl)c(C(C)C(O)(c3ccnc(Cl)c3)C(F)(F)F)c2)cn1 -US20110312951A1,2,Cc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)c1.Nc1ccc(Oc2ccnc3[nH]c(=O)c4c(c23)CCCC4)cc1>>Cc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)c5c(c34)CCCC5)cc2)c1 -US20100120739A1,2,NN.O=C(O)Cc1ccc2ncc(Br)cc2c1F>>NNC(=O)Cc1ccc2ncc(Br)cc2c1F -US20080287394A1,3,CN1CCn2c(c(OCc3ccccc3)c3c(=O)n(Cc4ccc(F)cc4)nc(Br)c32)C1=O.OB(O)c1cncnc1>>CN1CCn2c(c(OCc3ccccc3)c3c(=O)n(Cc4ccc(F)cc4)nc(-c4cncnc4)c32)C1=O -US06329400B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[C@H](N)C(=O)O>>CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)C -US04224325,1,Cc1cc(C)n(-c2ccc(Cl)nn2)n1.NNCCO>>Cc1cc(C)n(-c2ccc(NNCCO)nn2)n1 -US05653914,8,C[SiH](C)OC(c1ccc(CO)cc1)C(C)(C)C>>C[SiH](C)OC(c1ccc(C=O)cc1)C(C)(C)C -US08349836B2,1,NCc1cc(Cl)cc(Cl)c1.O=c1[nH]nc(Cl)c2cc(Br)ccc12>>O=c1[nH]nc(Cl)c2cc(NCc3cc(Cl)cc(Cl)c3)ccc12 -US20120142667A1,7,COc1ccc(OCCCN2CCCCC2)cc1[N+](=O)[O-]>>COc1ccc(OCCCN2CCCCC2)cc1N -US20060041144A1,7,CCOc1ccc(-c2ncccc2[N+](=O)[O-])cc1OC>>CCOc1ccc(-c2ncccc2N)cc1OC -US06110962,1,COC(=O)C[C@H](O)C(=O)OC.Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br>>COC(=O)CC(Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br)C(=O)OC -US06964983B2,6,COC(=O)COc1cc(OC)c(SCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2C)cc1C>>COc1cc(OCC(=O)O)c(C)cc1SCc1ccc(-c2ccc(C(F)(F)F)cc2)cc1C -US06103708,6,COc1ccc(CCc2c(Cc3ccccc3)sc3ccccc23)cc1>>Oc1ccc(CCc2c(Cc3ccccc3)sc3ccccc23)cc1 -US20150133425A1,2,COCCNCCO.COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)O)C3>>COCCN(CCO)C(=O)C1CCc2c(sc3ncnc(Nc4cc5cn[nH]c5cc4OC)c23)C1 -US05705456,9,O=C1C(Br)CCN1c1ccc(F)c(Cl)c1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC1CCN(c2ccc(F)c(Cl)c2)C1=O -US07880007B2,1,CI.Oc1ccc(Cl)cc1Br>>COc1ccc(Cl)cc1Br -US06964961B2,1,CO[C@@H]1CCN(C(=O)c2cc3nccc(Cl)c3s2)C1.Cc1[nH]c2ccc(N)cc2c1Cl>>CO[C@@H]1CCN(C(=O)c2cc3nccc(Nc4ccc5[nH]c(C)c(Cl)c5c4)c3s2)C1 -US20070213339A1,7,O=[N+]([O-])c1ccc(CN2CCCC2)nc1>>Nc1ccc(CN2CCCC2)nc1 -US20020183285A1,3,C#C[Si](C)(C)C.CC(C)c1cc(OS(=O)(=O)C(F)(F)F)ccc1C(C)(C)O[SiH2]C(C)(C)C>>CC(C)c1cc(C#C[Si](C)(C)C)ccc1C(C)(C)O[SiH2]C(C)(C)C -US20030105077A1,1,Cc1ccccc1Cn1c(Br)nc2c1c(=O)[nH]c(=O)n2C.NC1CCCCNC1>>Cc1ccccc1Cn1c(N2CCCCC(N)C2)nc2c1c(=O)[nH]c(=O)n2C -US20110038876A1,7,CC(=O)OCc1cc2c(cc1[N+](=O)[O-])c(Br)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=O)OCc1cc2c(cc1N)c(Br)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US04321377,9,CCOC(=O)C1=CNC2=C(C(=O)N(C)C)CCC(C)N2C1=O.N>>CC1CCC(C(=O)N(C)C)=C2NC=C(C(N)=O)C(=O)N21 -US20110105509A1,1,COC(=O)CBr.Cc1[nH]c2ccc(F)cc2c1-c1ccc(Cl)nn1>>COC(=O)Cn1c(C)c(-c2ccc(Cl)nn2)c2cc(F)ccc21 -US20150038438A1,1,CN.Cn1ccc2cc3c(cc21)C=CCCC3=O>>CN=C1CCC=Cc2cc3c(ccn3C)cc21 -US20130324528A1,3,Nc1ccnc(Cl)c1.OB(O)c1cc(Cl)ccc1F>>Nc1ccnc(-c2cc(Cl)ccc2F)c1 -US08518972B2,2,COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc4ncc(CN5CCOCC5)n4c3)cccc2C1=O>>O=C1CCC(N2Cc3c(OCc4ccc5ncc(CN6CCOCC6)n5c4)cccc3C2=O)C(=O)N1 -US20100324000A1,6,CC(C)(C)OC(=O)NCCc1cccc(OCc2ccccc2)c1>>CC(C)(C)OC(=O)NCCc1cccc(O)c1 -US20120172351A1,3,COC(=O)C[C@@H]1COc2cc(NCc3ccc(C)c(Br)c3C)ccc21.COc1ccc(B(O)O)cn1>>COC(=O)C[C@@H]1COc2cc(NCc3ccc(C)c(-c4ccc(OC)nc4)c3C)ccc21 -US08119661B2,2,CC1(N2CCC(N3C(=O)N[C@@H]4CCCC[C@@H]43)CC2)CCNCC1.CCOC(=O)Cl>>CCOC(=O)N1CCC(C)(N2CCC(N3C(=O)N[C@@H]4CCCC[C@@H]43)CC2)CC1 -US20080076762A1,2,CC(C)(C)OC(=O)N1CCC(NCc2ccc(Br)cc2)CC1.CCCCCc1ccc(C(=O)O)nc1>>CCCCCc1ccc(C(=O)N(Cc2ccc(Br)cc2)C2CCN(C(=O)OC(C)(C)C)CC2)nc1 -US20140357858A1,1,CI.O=C1CC(=O)N(c2ccc(NS(=O)(=O)c3cccc(Br)c3)cc2)c2ccc3ccccc3c2N1>>CN(c1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1)S(=O)(=O)c1cccc(Br)c1 -US20040192680A1,2,NCCCCO.O=C(O)/C=C/c1c(F)cccc1Sc1ccc(Cl)cc1>>O=C(/C=C/c1c(F)cccc1Sc1ccc(Cl)cc1)NCCCCO -US20140235584A1,1,CI.Cn1nnnc1Nc1ccc(Br)cn1>>CN(c1ccc(Br)cn1)c1nnnn1C -US08084620B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CN1CCN(C(=O)c2ccc3c(c2)[nH]c2c(C(N)=O)ccc(Br)c23)CC1>>CN1CCN(C(=O)c2ccc3c(c2)[nH]c2c(C(N)=O)ccc(B4OC(C)(C)C(C)(C)O4)c23)CC1 -US20080249071A1,10,CC(C)(C)C(=O)CC#N.O=C1CCC(=O)N1Br>>CC(C)(C)C(=O)C(Br)C#N -US20100016586A1,1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(CCn2c(Br)nc3c(N)ncnc32)CC1.Sc1nc2cccc(Cl)c2s1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(CCn2c(Sc3nc4cccc(Cl)c4s3)nc3c(N)ncnc32)CC1 -US20120202287A1,6,CCCCCC[C@@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)n1cnc2c(N)ncnc21>>CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc21 -US08293925B2,1,CCNC.COC(=O)C1(CI)CN(c2c(C)cccc2C)C(=O)C1C>>CCN(C)CC1(C(=O)OC)CN(c2c(C)cccc2C)C(=O)C1C -US20070254881A1,4,COC(=O)C(=O)CC(=O)c1ccc(C#N)cn1.NNc1ccc(Cl)nn1>>COC(=O)c1cc(-c2ccc(C#N)cn2)n(-c2ccc(Cl)nn2)n1 -US05120759,2,CC(C)[C@@H]1c2ccc(F)cc2CC[C@@]1(O)CCO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC[C@]2(O)CCc3cc(F)ccc3[C@H]2C(C)C)cc1 -US04442109,1,C[S-].Cn1cc(CCl)c(=O)c2ccc(C(F)(F)F)cc21>>CSCc1cn(C)c2cc(C(F)(F)F)ccc2c1=O -US06033601,3,CCCCCC(=O)Cl.Cc1ccc(S(=O)(=O)n2ccc3ccccc32)cc1>>CCCCCC(=O)c1cn(S(=O)(=O)c2ccc(C)cc2)c2ccccc12 -US04216326,7,c1ccc(Cc2cccnc2)cc1>>c1ccc(CC2CCCNC2)cc1 -US06878750B2,6,COc1ccc(C2=C(c3ccc(O)cc3)CCCc3cc(OCc4ccccc4)ccc32)cc1>>COc1ccc(C2=C(c3ccc(O)cc3)CCCc3cc(O)ccc32)cc1 -US08030327B2,7,CC(=O)c1ccc(Br)cc1Cl>>C[C@H](O)c1ccc(Br)cc1Cl -US20150274696A1,1,COc1ccc(CS)cc1.O=[N+]([O-])c1cnc(Cl)cc1Cl>>COc1ccc(CSc2cc(Cl)ncc2[N+](=O)[O-])cc1 -US20080058332A1,2,CN1CCC(C(=O)O)CC1.Nc1cccc(-c2nc(-c3cccc(CO)c3)cc(N3CCOCC3)n2)c1>>CN1CCC(C(=O)Nc2cccc(-c3nc(-c4cccc(CO)c4)cc(N4CCOCC4)n3)c2)CC1 -US20100010037A1,3,COc1cc(B(O)O)c(Cl)cc1Cl.C[Si](C)(C)CCOCn1cc(C#N)c2c(Cl)ccnc21>>COc1cc(-c2ccnc3c2c(C#N)cn3COCC[Si](C)(C)C)c(Cl)cc1Cl -US20130338367A1,2,CNc1cn(-c2cccnc2)nc1Cl.CSCCC(=O)O>>CSCCC(=O)N(C)c1cn(-c2cccnc2)nc1Cl -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1.COc1cccc(OCCCCCCl)c1>>COc1cccc(OCCCCCN2CCC(CNC(=O)c3cc(Cl)c(N)cc3OC)CC2)c1 -US07285563B2,3,NC(=O)c1ccc(Cl)nc1.OB(O)c1ccc(F)cc1>>NC(=O)c1ccc(-c2ccc(F)cc2)nc1 -US20140107109A1,1,C[C@@]1(c2cc(N)ccc2F)CS(=O)(=O)C2(CCOC2)C(N)=N1.Clc1cnc2c(Cl)nccc2c1>>C[C@@]1(c2cc(Nc3nccc4cc(Cl)cnc34)ccc2F)CS(=O)(=O)C2(CCOC2)C(N)=N1 -US20070054909A1,2,COC(=O)c1ccc(OC[C@@H]2CC[C@H](c3ccccc3)N2)cc1.COc1cc(CC(=O)O)ccc1NC(=O)Nc1ccccc1Cl>>COC(=O)c1ccc(OC[C@@H]2CC[C@H](c3ccccc3)N2C(=O)Cc2ccc(NC(=O)Nc3ccccc3Cl)c(OC)c2)cc1 -US20070197533A1,2,CC(C)(C)OC(=O)N[C@H]1C[C@@H](NC(=O)OC(C)(C)C)CN(c2nc(Nc3ccc(N)c(OCc4ccccc4)c3)nc(N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](NC(=O)OC(C)(C)C)C3)n2)C1.COc1cccc(O)c1C(=O)O>>COc1cccc(O)c1C(=O)Nc1ccc(Nc2nc(N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](NC(=O)OC(C)(C)C)C3)nc(N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](NC(=O)OC(C)(C)C)C3)n2)cc1OCc1ccccc1 -US20140296272A1,3,CC1(C)OB(c2ccc3ncsc3c2)OC1(C)C.COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1Cl)CCCC3>>COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc2ncsc2c1)CCCC3 -US08088760B2,10,COC(=O)c1cc(F)cc2nc(-c3ccc(C)cc3)oc12.O=C1CCC(=O)N1Br>>COC(=O)c1cc(F)cc2nc(-c3ccc(CBr)cc3)oc12 -US20140363452A1,6,CC[C@H](C)[C@@H]([C@@H](CC(=O)OC(C)(C)C)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCC1c2ccccc2-c2ccccc21)C(C)C>>CC[C@H](C)[C@@H]([C@@H](CC(=O)O)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCC1c2ccccc2-c2ccccc21)C(C)C -US06593333B1,2,COCC(=O)Cl.Nc1cc([N+](=O)[O-])ccc1F>>COCC(=O)Nc1cc([N+](=O)[O-])ccc1F -US20030008882A1,7,COc1ccccc1C=C(C)C>>COc1ccccc1CC(C)C -USRE041315E1,1,CCCCBr.Cc1ccc(N2CCNCC2)cc1[N+](=O)[O-]>>CCCCN1CCN(c2ccc(C)c([N+](=O)[O-])c2)CC1 -US08269002B2,1,CCOC(=O)[C@H](C)O.Fc1cccc(CSc2nc(Cl)cc(Cl)n2)c1F>>CCOC(=O)[C@H](C)Oc1cc(Cl)nc(SCc2cccc(F)c2F)n1 -US07183277B2,2,O=C(O)[C@H](O)c1ccccc1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)O[C@@H](C(=O)O)c1ccccc1 -US20140336190A1,3,Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1.Cc1noc(C)c1-c1cc(I)c2nc(NS(C)(=O)=O)[nH]c2c1>>Cc1n[nH]c(C)c1-c1cc(-c2c(C)noc2C)cc2[nH]c(NS(C)(=O)=O)nc12 -US20130018033A1,1,CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)c2cc(C)cc3c(Cl)ncnc23)c1F.NC1CCCC1>>CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)c2cc(C)cc3c(NC4CCCC4)ncnc23)c1F -US03984573,2,CCCO.O=C(O)c1ccccc1S>>CCCOC(=O)c1ccccc1S -US20140206702A1,1,N#Cc1cccc(F)c1-c1nc2ccnc(Br)c2[nH]1.Nc1cc(N)ncn1>>N#Cc1cccc(F)c1-c1nc2ccnc(Nc3cc(N)ncn3)c2[nH]1 -US20070066624A1,1,N#Cc1ccc(Oc2ccc(CBr)cn2)cc1.O=C1N(C2CCOCC2)C[C@@H](c2ccccc2)N1C1CCNCC1>>N#Cc1ccc(Oc2ccc(CN3CCC(N4C(=O)N(C5CCOCC5)C[C@H]4c4ccccc4)CC3)cn2)cc1 -US20090082378A1,1,CN.O=[N+]([O-])c1cccc(CCl)c1>>CNCc1cccc([N+](=O)[O-])c1 -US08106057B2,1,BrCc1ccccc1.C=C(C)c1cc(C(=O)Nc2ccc(CN3CCOCC3)cc2)c(OCc2ccccc2)cc1OCc1ccccc1>>C=C(C)c1cc(C(=O)N(Cc2ccccc2)c2ccc(CN3CCOCC3)cc2)c(OCc2ccccc2)cc1OCc1ccccc1 -US07935724B2,6,COC(=O)c1ccc2cc(C(=O)NOC(c3ccccc3)(c3ccccc3)c3ccccc3)sc2c1>>O=C(O)c1ccc2cc(C(=O)NOC(c3ccccc3)(c3ccccc3)c3ccccc3)sc2c1 -US20080255124A1,2,CS(=O)(=O)Cl.N#Cc1ccc(N(CCO)CC(F)(F)F)cc1C(F)(F)F>>CS(=O)(=O)OCCN(CC(F)(F)F)c1ccc(C#N)c(C(F)(F)F)c1 -US08026247B2,9,Nc1nc(Cl)cc(Oc2ccc3c(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cccc3c2)n1>>Nc1nccc(Oc2ccc3c(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cccc3c2)n1 -US04650800,1,O=C(CBr)c1ccsc1.O=c1ncc(Cl)c[nH]1>>O=C(Cn1cc(Cl)cnc1=O)c1ccsc1 -US07919502B2,2,C1CN[C@H](CN2CCCC2)C1.O=C(O)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1>>O=C(c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1)N1CCC[C@H]1CN1CCCC1 -US06410554B1,3,CC[Mg+].O=Cc1ccc(F)c(F)c1>>CCC(O)c1ccc(F)c(F)c1 -US07842713B2,1,Cn1ccc(NC(=O)c2cc(O)c3c(c2)OC(C)(C)C3)n1.FC(F)c1ccc(Br)cc1>>Cn1ccc(NC(=O)c2cc(Oc3ccc(C(F)F)cc3)c3c(c2)OC(C)(C)C3)n1 -US20100267708A1,2,Clc1cc(NC2CCOCC2)c2[nH]c(C3=N[C@H](CCN4CCNCC4)CS3)cc2c1.O=C(O)Cn1cnnn1>>O=C(Cn1cnnn1)N1CCN(CC[C@@H]2CSC(c3cc4cc(Cl)cc(NC5CCOCC5)c4[nH]3)=N2)CC1 -US08609669B2,2,CC(C)(C)c1c(N)nn2cccnc12.CC(C)(CC(=O)Cl)c1ccccc1>>CC(C)(C)c1c(NC(=O)CC(C)(C)c2ccccc2)nn2cccnc12 -US04990521,6,CO[C@@H]1CN(Cc2ccccc2)CC[C@H]1NC(=O)c1cccc(C(F)(F)F)c1>>CO[C@@H]1CNCC[C@H]1NC(=O)c1cccc(C(F)(F)F)c1 -US03971797,7,CC(=O)OCc1cnc(C)c(OC(C)=O)c1C=O>>CC(=O)OCc1cnc(C)c(OC(C)=O)c1CO -US20090221640A1,1,C[C@H](N)C(=O)OC(C)(C)C.O=Cc1ccc2ccccc2c1>>C[C@H](N=Cc1ccc2ccccc2c1)C(=O)OC(C)(C)C -US06900319B2,1,CI.Cc1ccc(C#N)cc1O>>COc1cc(C#N)ccc1C -US08772323B2,3,Brc1ccc2nc(-c3ccc(OCc4ccccc4)cc3)oc2c1.CCCC(=O)N(C)OC>>CCCC(=O)c1ccc2nc(-c3ccc(OCc4ccccc4)cc3)oc2c1 -US08058269B2,1,CC(C)(C)OC(=O)N1CCNCC1.O=C1Nc2cc(Cl)ccc2C1(Br)Cc1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CCN(C2(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc32)CC1 -US07132425B2,7,CC[Si](CC)(CC)OCCNc1cnc([N+](=O)[O-])cn1>>CC[Si](CC)(CC)OCCNc1cnc(N)cn1 -US20150038488A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ncc(I)[nH]1>>Cc1ncc(I)n1C(=O)OC(C)(C)C -US05292956,1,CC(C)(C)c1cc(CCNCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O.CCCCCCCCBr>>CCCCCCCCN(CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 -US08067396B2,7,CC(=O)N[C@](C)(CCc1ccc(C#CCCCc2ccccc2)o1)COC(C)=O>>CC(=O)N[C@](C)(CCc1ccc(CCCCCc2ccccc2)o1)COC(C)=O -US08063046B2,2,COc1ccc(C(=O)O)cc1/C=C/c1ccc(OC(F)(F)F)cc1.NCCO>>COc1ccc(C(=O)NCCO)cc1/C=C/c1ccc(OC(F)(F)F)cc1 -US08247430B2,1,CN.N#Cc1ccnc(Cl)c1>>CNc1cc(C#N)ccn1 -US08716303B2,9,OC(O)Cc1cc(F)c(F)nc1F>>OCCc1cc(F)c(F)nc1F -US20140378487A1,1,O=Cc1ccc(Cl)nc1.Oc1cccc(C(F)(F)F)c1>>O=Cc1ccc(Oc2cccc(C(F)(F)F)c2)nc1 -US20140336108A1,6,Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCNC(=O)OC(C)(C)C)sc34)cc2)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN)sc34)cc2)c1 -US07838643B2,6,CCOC(=O)CN1CC[N+](C)(C)CC1>>C[N+]1(C)CCN(CC(=O)O)CC1 -US04755212,1,CI.Nc1c(Cl)cccc1CO>>COCc1cccc(Cl)c1N -US04159331,2,CN(C)S(=O)(=O)Cl.O=S(=O)(c1ccc(Nc2ccnc3cc(C(F)(F)F)ccc23)cc1)N1CCNCC1>>CN(C)S(=O)(=O)N1CCN(S(=O)(=O)c2ccc(Nc3ccnc4cc(C(F)(F)F)ccc34)cc2)CC1 -US20140288045A1,6,CCOC(=O)CNc1cc(I)c(Cl)cc1OC>>COc1cc(Cl)c(I)cc1NCC(=O)O -US08436008B2,1,C1CNCCNC1.CC1Cc2ccc(-c3cnn(C)c3)cc2CN1c1cc(Cl)nc(N)n1>>CC1Cc2ccc(-c3cnn(C)c3)cc2CN1c1cc(N2CCCNCC2)nc(N)n1 -US20080004309A1,2,CCOC(=O)c1nc(C)c2nc(-c3ccccc3)sc2c1O.NCC(=O)O>>Cc1nc(C(=O)NCC(=O)O)c(O)c2sc(-c3ccccc3)nc12 -US20120064107A1,1,C#CCCCCCl.O=C(NC(=O)OCc1ccccc1)OCc1ccccc1>>C#CCCCCN(C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 -US20120309966A1,2,NCc1nccnc1Cl.O=C(NC[C@@H]1CC[C@@H](C(=O)O)CC1)OCc1ccccc1>>O=C(NC[C@@H]1CC[C@@H](C(=O)NCc2nccnc2Cl)CC1)OCc1ccccc1 -US04075342,4,Cc1ccccc1C(=O)CC(=O)c1ccccc1.NN>>Cc1ccccc1-c1cc(-c2ccccc2)n[nH]1 -US20110144129A1,1,CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)CC[C@@H](N)C1.COC1COCCC1=O>>CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)CC[C@@H](N[C@H]2CCOC[C@H]2OC)C1 -US20110144129A1,1,CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)CC[C@@H](N)C1.COC1COCCC1=O>>CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)CC[C@@H](N[C@@H]2CCOC[C@H]2OC)C1 -US04535171,8,OCc1ccc2c(c1)Sc1ccc(F)cc1C=C2>>O=Cc1ccc2c(c1)Sc1ccc(F)cc1C=C2 -US20150166549A1,1,CC(c1oc(=O)c2ccccc2c1C1=CCNCC1)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21.O=Cc1ccncc1>>CC(c1oc(=O)c2ccccc2c1C1=CCN(Cc2ccncc2)CC1)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21 -US08030354B2,1,C=CC(C)(C)C(O)c1cc(C(=O)OC)ccc1-c1cc(OC)ccc1F.CI>>C=CC(C)(C)C(OC)c1cc(C(=O)OC)ccc1-c1cc(OC)ccc1F -US20140121246A1,3,C#Cc1ccc(OC)c(F)c1.CCOC(=O)Cl>>CCOC(=O)C#Cc1ccc(OC)c(F)c1 -US20140066455A1,6,COC(=O)c1cnc(C2CCN(C(=O)OC(C)(C)C)CC2)cn1>>COC(=O)c1cnc(C2CCNCC2)cn1 -US07115749B2,1,CC(C)(C)CO.CCOC(=O)Cn1nc(C(=O)OCC)cc1O>>CCOC(=O)Cn1nc(C(=O)OCC)cc1OCC(C)(C)C -US07229987B2,1,ClCc1cc(-c2ccc(OC3CCCCO3)cc2)no1.SCCOc1ccccc1>>c1ccc(OCCSCc2cc(-c3ccc(OC4CCCCO4)cc3)no2)cc1 -US07851473B2,2,CSc1cccc(N=C=O)c1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>CSc1cccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)c1 -US20100056531A1,1,CCOC(=O)CCl.Nc1c[nH]c2cccnc12>>CCOC(=O)CNc1c[nH]c2cccnc12 -US07345038B2,1,CNC1CCCC1.ClCc1ccc(Cl)nc1>>CN(Cc1ccc(Cl)nc1)C1CCCC1 -US04656308,2,CCOC(=O)C(=O)OCC.NCCO>>CCOC(=O)C(=O)NCCO -US20040058903A1,1,NCCc1cscn1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(NCCc2cscn2)cc1 -US20150232481A1,1,C=[N+]=[N-].O=C(O)c1cc(F)c(F)cc1Br>>COC(=O)c1cc(F)c(F)cc1Br -US04888025,1,CC(=O)Nc1ccc(O)cc1[N+](=O)[O-].ClCC1CO1>>CC(=O)Nc1ccc(OCC2CO2)cc1[N+](=O)[O-] -US20060004017A1,1,CC1=CC(C)(C)Nc2ccc(O)cc21.COc1cc2c(Cl)ncnc2cc1OCCCN1CCCC1>>COc1cc2c(Oc3ccc4c(c3)C(C)=CC(C)(C)N4)ncnc2cc1OCCCN1CCCC1 -US08546374B2,3,CCCC[Sn](CCCC)(CCCC)c1cccnc1.N#Cc1cccnc1Cl>>N#Cc1cccnc1-c1cccnc1 -US20130195848A1,3,CSc1nc(Br)cn2c(I)cnc12.O=C(NC1CC1)c1ccc(B(O)O)cc1>>CSc1nc(Br)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 -US05849759,7,CC(C)c1nc2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)c([N+](=O)[O-])c2n1Cc1ccc(C#N)c2ccccc12>>CC(C)c1nc2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)c(N)c2n1Cc1ccc(C#N)c2ccccc12 -US04515948,7,C=CCOc1cc(C(=O)CS(C)(=O)=O)cc(OCC=C)c1NC(C)=O>>C=CCOc1cc(C(O)CS(C)(=O)=O)cc(OCC=C)c1NC(C)=O -US20140121222A1,1,Brc1ncnc2[nH]cnc12.Cc1csc2nc(C(C)N)c(-c3cccc(F)c3)c(=O)n12>>Cc1csc2nc(C(C)Nc3ncnc4[nH]cnc34)c(-c3cccc(F)c3)c(=O)n12 -US20030207924A1,1,COC(=O)COc1c(C)cc(S)cc1C.Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCl>>COC(=O)COc1c(C)cc(SCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C -US08618094B2,7,C=C(C=O)C[C@]1(C(=O)OC(C)(C)C)CC(=O)N([C@H](C)c2ccccc2)C1>>C=C(CO)C[C@]1(C(=O)OC(C)(C)C)CC(=O)N([C@H](C)c2ccccc2)C1 -US07598264B2,6,CCOC(=O)c1ncc(OC)c2c1CCN(Cc1ccc(F)cc1)C2=O>>COc1cnc(C(=O)O)c2c1C(=O)N(Cc1ccc(F)cc1)CC2 -US20130029962A1,2,COc1cc(C(C)C(=O)O)cnc1NS(C)(=O)=O.NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1>>COc1cc(C(C)C(=O)NCc2cc(C(F)(F)F)nn2-c2cccc(Cl)c2)cnc1NS(C)(=O)=O -US20140121224A1,2,Cc1cccc(N)c1C(=O)O.Nc1ccccc1>>Cc1cccc(N)c1C(=O)Nc1ccccc1 -US04168385,1,COC(=O)C(Br)c1ccc(Oc2ccc(Cl)cc2)cc1.Oc1ccc(C2CCCCC2)cc1>>COC(=O)C(Oc1ccc(C2CCCCC2)cc1)c1ccc(Oc2ccc(Cl)cc2)cc1 -US08158796B2,1,CC(C)(C)OC(=O)N1CCC(=O)C1.Nc1cccc2cnccc12>>CC(C)(C)OC(=O)N1CCC(Nc2cccc3cnccc23)C1 -US20080269200A1,3,NC(=O)c1cc(Br)cc2cc[nH]c12.O=C(O)c1cccc(B(O)O)c1>>NC(=O)c1cc(-c2cccc(C(=O)O)c2)cc2cc[nH]c12 -US20090036428A1,6,COC(=O)c1ccnc(-c2ccc(OCc3ccccc3)c(C#N)c2)c1>>COC(=O)c1ccnc(-c2ccc(O)c(C#N)c2)c1 -US20070293521A1,7,CCOC(=O)COc1ccc([N+](=O)[O-])cc1>>CCOC(=O)COc1ccc(N)cc1 -US06825191B2,2,C1CCNC1.O=C(O)c1ccc2c(c1)N(Cc1ccc(OC3CCNCC3)cc1)C(=O)CN(C(=O)c1ccc(Cl)cc1)C2>>O=C(c1ccc2c(c1)N(Cc1ccc(OC3CCNCC3)cc1)C(=O)CN(C(=O)c1ccc(Cl)cc1)C2)N1CCCC1 -US04478837,9,Clc1cc2c(nn1)CCCCCC2.NN>>NNc1cc2c(nn1)CCCCCC2 -US20070032522A1,1,CCOC(=O)c1c[nH]c2cc(F)c(F)cc2c1=O.Clc1ccc(CBr)cc1>>CCOC(=O)c1cn(Cc2ccc(Cl)cc2)c2cc(F)c(F)cc2c1=O -US20020156081A1,1,CN1CCNCC1.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)nc1)nn2C1CCC(=O)CC1>>CN1CCN([C@@H]2CC[C@H](n3nc(-c4ccc(Oc5ccccc5)nc4)c4c(N)ncnc43)CC2)CC1 -US07307094B2,2,N[C@@H]1CN2CCC1CC2.O=C(O)c1cccc2oc(-c3ccc(Cl)s3)nc12>>O=C(N[C@@H]1CN2CCC1CC2)c1cccc2oc(-c3ccc(Cl)s3)nc12 -US06172085B2,1,CCOC(=O)N1CCC(=O)CC1.NC(c1ccccc1)c1ccccc1>>CCOC(=O)N1CCC(NC(c2ccccc2)c2ccccc2)CC1 -US20130040930A1,1,CI.Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)NC(=O)C4C)cc3C)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)N(C)C(=O)C4C)cc3C)CC2)c(C)c1 -US06583156B1,1,CI.OC(c1ccccc1)c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12>>COC(c1ccccc1)c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12 -US04839381,2,CCCCOC(=O)CCCCCN=C=O.Cc1c(C(=O)OC(C)C)sc(C(=O)OC(C)C)c1O>>CCCCOC(=O)CCCCCNC(=O)Oc1c(C(=O)OC(C)C)sc(C(=O)OC(C)C)c1C -US20040097545A1,7,Nc1ccc(Br)cc1[N+](=O)[O-]>>Nc1ccc(Br)cc1N -US20130216497A1,9,CCC1CC(CCCC(N)=O)CC1c1nnc2cnc3[nH]ccc3n12>>CC[C@@H]1C[C@H](CCCC#N)C[C@@H]1c1nnc2cnc3[nH]ccc3n12 -US08426437B2,2,Nc1ccc2[nH]c(=O)c3[nH]ccc3c2c1.O=S(=O)(Cl)c1ccccc1>>O=c1[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc2c2cc[nH]c12 -US08124629B2,9,CCS(=O)(=O)c1ccc(Cc2c(C)c(CO)cc3ccc(F)cc23)cc1.ClC(Cl)(Cl)Cl>>CCS(=O)(=O)c1ccc(Cc2c(C)c(CCl)cc3ccc(F)cc23)cc1 -US06498172B1,2,COC(=O)CCc1cccc(CNCc2ccc(-n3cccn3)cc2)c1.O=S(=O)(Cl)c1ccccc1>>COC(=O)CCc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2ccccc2)c1 -US20120225859A1,1,C[S-].Nc1ccnc(Cl)c1>>CSc1cc(N)ccn1 -US08563576B2,3,Brc1csc(Br)n1.CON(C)C(=O)c1cccnc1F>>O=C(c1nc(Br)cs1)c1cccnc1F -US04722922,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.COC(=O)CCCCN>>COC(=O)CCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C -US20050059713A1,1,O=Cc1ccc(F)cc1.Oc1ccc(C(F)(F)F)cn1>>O=Cc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1 -US08247401B2,3,CC(C)(C)OC(=O)c1cc(Br)cc(C(N)C(F)(F)F)c1.Cc1ccc([Zn]Br)nc1>>Cc1ccc(-c2cc(C(=O)OC(C)(C)C)cc(C(N)C(F)(F)F)c2)nc1 -US08791102B2,6,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1>>O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1CN(C(=O)OCc2ccccc2)CCN1 -US20150038460A1,3,C#C[C@@](C)(O)c1cc(C)on1.CC(C)(O)c1nn(-c2ccnc(N)n2)c2cc(Br)ccc12>>Cc1cc([C@](C)(O)C#Cc2ccc3c(C(C)(C)O)nn(-c4ccnc(N)n4)c3c2)no1 -US20040072820A1,1,COc1cccc(-c2ccc3cc(OC)ccc3c2O)c1.O=Cc1ccc(F)cc1>>COc1cccc(-c2ccc3cc(OC)ccc3c2Oc2ccc(C=O)cc2)c1 -US20080249125A1,1,CNC(=O)C(Br)c1ccccc1.COc1ccc(CCC2NCCc3ncccc32)cc1>>CNC(=O)C(c1ccccc1)N1CCc2ncccc2C1CCc1ccc(OC)cc1 -US08013001B2,7,C#Cc1ccc(C#N)c(F)c1>>CCc1ccc(C#N)c(F)c1 -US20040147748A1,3,COc1ccccc1B(O)O.Nc1cnc(Br)cn1>>COc1ccccc1-c1cnc(N)cn1 -US09133157B2,1,CC(C)S(=O)(=O)n1ncc2cc(Br)ccc21.COC(=O)CCS(=O)[O-]>>COC(=O)CCS(=O)(=O)c1ccc2c(cnn2S(=O)(=O)C(C)C)c1 -US20150051177A1,2,CNc1ccccc1OC.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>COc1ccccc1N(C)S(=O)(=O)c1ccc(C(=O)O)cc1 -US20150023916A1,7,CCOc1ccc(CNc2ncc(Br)cc2[N+](=O)[O-])cc1>>CCOc1ccc(CNc2ncc(Br)cc2N)cc1 -US20120142705A1,7,O=C1C(=O)N(C(CC2CCCC2)C(=O)O)c2cc(Cl)ccc21>>O=C(O)C(CC1CCCC1)N1C(=O)Cc2ccc(Cl)cc21 -US20100120784A1,6,CCOC(=O)Cn1nnc(-c2cc(OCc3ccc(OC)cc3)no2)n1>>CCOC(=O)Cn1nnc(-c2cc(O)no2)n1 -US05420287,3,CSc1ccc(C2=C(Br)CCC2)cc1.Cc1ccc(B(O)O)cc1>>CSc1ccc(C2=C(c3ccc(C)cc3)CCC2)cc1 -US20140336108A1,1,COC(=O)CBr.Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN)sc34)cc2F)c1>>COC(=O)CNCCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1 -US20110053980A1,1,CNC.O[C@H]1CCc2ccc(Br)cc21>>CN(C)[C@@H]1CCc2ccc(Br)cc21 -US20150252038A1,1,COC(=O)c1cc(C2CC2)c(OC[C@H]2CCCNC2)cc1F.ClCc1cc(Cl)cc(Cl)c1>>COC(=O)c1cc(C2CC2)c(OC[C@H]2CCCN(Cc3cc(Cl)cc(Cl)c3)C2)cc1F -US20060004049A1,1,CCOC(=O)[C@H]1CCCNC1.Fc1cc(-c2ccncc2)ccc1Br>>CCOC(=O)[C@H]1CCCN(c2ccc(-c3ccncc3)cc2F)C1 -US20100331306A1,1,CC(c1nc2ccc(F)cc2c(Cl)c1-c1ccccc1)N1C(=O)c2ccccc2C1=O.COCCN>>COCCNc1c(-c2ccccc2)c(C(C)N2C(=O)c3ccccc3C2=O)nc2ccc(F)cc12 -US05932594,1,BrCCc1ccccc1.N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCNC1>>N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCN(CCc2ccccc2)C1 -US06277838B1,8,O=C(OO)c1cccc(Cl)c1.c1ccc(CSc2ccccc2)cc1>>O=S(Cc1ccccc1)c1ccccc1 -US08853208B2,7,CS(=O)(=O)CCN1C2CCC1CC(Oc1ccc([N+](=O)[O-])cc1)C2>>CS(=O)(=O)CCN1C2CCC1CC(Oc1ccc(N)cc1)C2 -US08609696B2,4,Nc1ccccc1N.O=C(O)C1CCNCC1>>c1ccc2[nH]c(C3CCNCC3)nc2c1 -US04284628,2,O=C(Cl)Oc1ccccc1.O=C(NC(Oc1ccccc1)C(Cl)(Cl)Cl)c1ccccc1O>>O=C(Oc1ccccc1)Oc1ccccc1C(=O)NC(Oc1ccccc1)C(Cl)(Cl)Cl -US05559266,1,CC(=O)Nc1c(I)c(C(=O)[O-])c(I)c(N(C)C(C)=O)c1I.O=C(Oc1ccccc1)OC(Cl)c1ccccc1>>CC(=O)Nc1c(I)c(C(=O)OC(OC(=O)Oc2ccccc2)c2ccccc2)c(I)c(N(C)C(C)=O)c1I -US20040097518A1,1,C[C@H](NC(=O)c1c(CBr)c(-c2ccccc2)nc2ccccc12)C1CCCCC1.O=C1CNCCN1c1ccccc1>>C[C@H](NC(=O)c1c(CN2CCN(c3ccccc3)C(=O)C2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1 -US07994176B2,3,O=C1C(N2CCC(F)(F)CC2)CCN1Cc1c(Cl)cc(OS(=O)(=O)C(F)(F)F)cc1Cl.OB(O)c1ccc(-c2ccccc2)cc1>>O=C1C(N2CCC(F)(F)CC2)CCN1Cc1c(Cl)cc(-c2ccc(-c3ccccc3)cc2)cc1Cl -US20120190679A1,6,CN(C)CCC(NC(=O)C1(NC(=O)OC(C)(C)C)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1>>CN(C)CCC(NC(=O)C1(N)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1 -US07622605B2,2,CC(=O)Cl.CCc1cc(Br)ccc1CN>>CCc1cc(Br)ccc1CNC(C)=O -US20110124633A1,2,CNCc1ccc2ccccc2c1.Nc1ncc(/C=C/C(=O)O)cc1CN1CCCC1>>CN(Cc1ccc2ccccc2c1)C(=O)/C=C/c1cnc(N)c(CN2CCCC2)c1 -US04443466,7,Cc1ccccc1C(=O)c1nc[nH]c1C>>Cc1ccccc1Cc1nc[nH]c1C -US08980879B2,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CN1C=CC(CS(C)(=O)=O)=c2ccc3c4c([nH]c(=O)c-4c21)=CCN3>>CN1C=CC(CS(C)(=O)=O)=c2ccc3c4c([nH]c(=O)c-4c21)=CCN3C1CCN(C(=O)OC(C)(C)C)CC1 -US08138181B2,4,O=C(OCc1ccccc1)N1CC=CC1.O=C(OO)c1cccc(Cl)c1>>O=C(OCc1ccccc1)N1CC2OC2C1 -US05883098,1,BrCc1ccccc1.CC(C)(C)OC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N(Cc1ccccc1)[C@@H](Cc1ccc2ccccc2c1)C(=O)OCc1ccccc1 -US20070185133A1,1,CC1(C)C(=O)NC(=O)N1CCNc1nccc(-c2ccc(I)s2)n1.CCc1ccccc1S>>CCc1ccccc1Sc1ccc(-c2ccnc(NCCN3C(=O)NC(=O)C3(C)C)n2)s1 -US20140171408A1,7,CC(C)(C)OC(=O)Nc1cc(C=O)ncn1>>CC(C)(C)OC(=O)Nc1cc(CO)ncn1 -US07671043B2,2,CNOC.COC(=O)c1ccc(C(=O)O)nc1>>COC(=O)c1ccc(C(=O)N(C)OC)nc1 -US06235731B1,6,CC(C)(C)OC(=O)N1CCC(CCCNC(=O)C2=Cc3cnc4cccc(n34)S2)CC1>>O=C(NCCCC1CCNCC1)C1=Cc2cnc3cccc(n23)S1 -US20140073634A1,1,CC(C)Oc1ccc(-c2nnc(-c3ccc(=O)[nH]n3)o2)cc1.CS(=O)(=O)C1CCN(c2cccc(CCl)c2)CC1>>CC(C)Oc1ccc(-c2nnc(-c3ccc(=O)n(Cc4cccc(N5CCC(S(C)(=O)=O)CC5)c4)n3)o2)cc1 -US20040030129A1,2,C1CCNCC1.COC1=C(OC)C(=O)C(Cc2ccc(CC(=O)O)cc2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(CC(=O)N3CCCCC3)cc2)=C(C)C1=O -US20080033016A1,2,COc1ccc(Cl)cc1C(=O)NCCC1CCN(S(N)(=O)=O)CC1.S=C=NC1CC1>>COc1ccc(Cl)cc1C(=O)NCCC1CCN(S(=O)(=O)NC(=S)NC2CC2)CC1 -US07557127B2,1,CCOC(=O)/C=C/c1ccc(N(C(=O)OC(C)(C)C)[C@@H]2CCNC2)nc1.COc1ccc(C=O)cc1>>CCOC(=O)/C=C/c1ccc(N(C(=O)OC(C)(C)C)[C@@H]2CCN(Cc3ccc(OC)cc3)C2)nc1 -US04363762,7,CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1ccccc1-2>>O=C1c2ccccc2-n2cnc(CO)c2[C@@H]2CCCN12 -US20110212956A1,2,CC(=O)OC(C)=O.NCCc1ccccc1F>>CC(=O)NCCc1ccccc1F -US07846964B2,7,Cc1sc(C(=O)C=Cc2ccc(C(=O)O)cc2)c2c1[C@H]1[C@@H](C2)C1(C)C>>Cc1sc(C(=O)CCc2ccc(C(=O)O)cc2)c2c1[C@H]1[C@@H](C2)C1(C)C -US20110130380A1,6,CCC1(CNc2nc(OC)ccc2F)CCOCC1>>CCC1(CNc2nc(O)ccc2F)CCOCC1 -US07414061B2,2,Cc1onc(-c2cccc(F)c2)c1-c1cn(-c2cccc(C(=O)O)c2)cn1.NC1CCCC1>>Cc1onc(-c2cccc(F)c2)c1-c1cn(-c2cccc(C(=O)NC3CCCC3)c2)cn1 -US04772755,3,C#Cc1ccccc1.O=C1C=CC(=O)C=C1>>O=C1C=CC(O)(C#Cc2ccccc2)C=C1 -US20120114765A1,2,NCCc1ccc(F)cc1.O=C(Cl)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(NCCc1ccc(F)cc1)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US20140309220A1,5,Fc1cccc2c1-n1cccc1C1(CCNCC1)O2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(N1CCC2(CC1)Oc1cccc(F)c1-n1cccc12)C(F)(F)F -US07910592B2,3,CON(C)C(=O)[C@H](C)NC(=O)OCc1ccccc1.FC(F)(F)c1cc(Br)cc(C(F)(F)F)c1>>C[C@H](NC(=O)OCc1ccccc1)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090181966A1,1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(O)cc2)c2ccccc21.COC(=O)C(C)CCCl>>COC(=O)[C@@H](C)CCOc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)CC2C)cc1 -US05807851,2,CC1Cc2cc(Cl)c(Cl)cc2C(c2ccc([N+](=O)[O-])cc2)=NN1.CN=C=O>>CNC(=O)N1N=C(c2ccc([N+](=O)[O-])cc2)c2cc(Cl)c(Cl)cc2CC1C -US20110212956A1,2,CC1NCCc2cccnc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2ncccc2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US04885292,7,CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)C(=O)c1nccs1>>CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@@H](O)c1nccs1 -US07064203B2,1,Nc1ccc(O)c(Cl)c1.OCc1ccccn1>>Nc1ccc(OCc2ccccn2)c(Cl)c1 -US06468502B1,2,CCCCCCCCCCN.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CCCCCCCCCCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F -US07915411B2,7,CC(Oc1ccc(Sc2ccc(O)cc2)c([N+](=O)[O-])c1)c1cccc(Br)c1>>CC(Oc1ccc(Sc2ccc(O)cc2)c(N)c1)c1cccc(Br)c1 -US20100256356A1,6,O=c1c(-c2ccc(OCc3ccccc3)c(F)c2)cncn1Cc1ccc(Cl)cc1>>O=c1c(-c2ccc(O)c(F)c2)cncn1Cc1ccc(Cl)cc1 -US06693123B2,1,COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(N)cc1-c1ccccc1.O=Cc1ncc[nH]1>>COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(NCc2ncc[nH]2)cc1-c1ccccc1 -US20120015928A1,2,CC(C)(C)OC(=O)N1CCN(c2ccc(C3(C(=O)O)CC3)c(F)c2)CC1.CC1(C)CC(=O)OC12CCNC2>>CC(C)(C)OC(=O)N1CCN(c2ccc(C3(C(=O)N4CCC5(C4)OC(=O)CC5(C)C)CC3)c(F)c2)CC1 -US06329405B1,1,CC(=O)Oc1ccc(C(C)N)cc1.COc1ccc(C(=O)c2cccc([N+](=O)[O-])c2)cc1>>COc1ccc(C(NC(C)c2ccc(OC(C)=O)cc2)c2cccc([N+](=O)[O-])c2)cc1 -US20070161627A1,7,COc1ccc2nccc(CCC3(O)CCN(N=O)CC3)c2n1>>COc1ccc2nccc(CCC3(O)CCN(N)CC3)c2n1 -US20050187266A1,6,CCOC(=O)C1(Oc2cccc(-c3cccc(OCc4ccccc4)c3)c2)CCC1>>CCOC(=O)C1(Oc2cccc(-c3cccc(O)c3)c2)CCC1 -US20150284382A1,1,CC(C)Nc1cc(Cl)ncc1C(=O)NC[C@@H](F)C(C)(C)O.N#Cc1cnc(N)nc1>>CC(C)Nc1cc(Nc2ncc(C#N)cn2)ncc1C(=O)NC[C@@H](F)C(C)(C)O -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4cn(CCC)nn4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cn(CCC)nn4)cc2)CCN3CC(C)C)cc1 -US05252735,1,ClCc1ccc2ccccc2n1.O=c1cc(-c2ccc(O)cc2)oc(N2CCOCC2)c1>>O=c1cc(-c2ccc(OCc3ccc4ccccc4n3)cc2)oc(N2CCOCC2)c1 -US20090215759A1,1,CNCC(=O)OCc1ccccc1.Cc1cc(Cl)nc(Cl)n1>>Cc1cc(N(C)CC(=O)OCc2ccccc2)nc(Cl)n1 -US20040186151A1,1,CC#CCBr.CCC1CCC(C(=O)NC(Cc2ccc(O)cc2)c2nc(-c3ccc(Cl)cc3Cl)c[nH]2)CC1>>CC#CCn1cc(-c2ccc(Cl)cc2Cl)nc1[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CC[C@@H](CC)CC1 -US20100216788A1,2,CC(C)(O)CC(=O)O.NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(Oc5ccccc5)c4)c(Cl)c3)c21>>CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(Oc5ccccc5)c4)c(Cl)c3)c21 -US20150183801A1,3,COc1ccc(B(O)O)cn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(NCCCO)c(Br)c1>>COc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2NCCCO)cn1 -US20020091147A1,1,C1COCCN1.Nc1ccc(CCC(=O)c2ccc(F)cc2)cc1>>Nc1ccc(CCC(=O)c2ccc(N3CCOCC3)cc2)cc1 -US20150175623A1,1,CN1CCN(CCO)CC1.Oc1ccc(Br)c(Cl)c1Cl>>CN1CCN(CCOc2ccc(Br)c(Cl)c2Cl)CC1 -US08048893B2,3,Cc1ccc(B(O)O)cc1.Cc1ccc(S(=O)(=O)n2cc(I)c(OCc3ccccc3)n2)cc1>>Cc1ccc(-c2cn(S(=O)(=O)c3ccc(C)cc3)nc2OCc2ccccc2)cc1 -US20130237562A1,3,CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1.CO[C@@H](C)Cn1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>CCOC(=O)c1cncc(-c2ccc3ncc4c(c3c2)n(C[C@H](C)OC)c(=O)n4C)c1 -US04962096,6,CCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OC=C1CCCC[N+]1(C)C)OCc1ccccc1>>CCCCCCCCCCCCCCCCOCC(O)COP(=O)([O-])OC=C1CCCC[N+]1(C)C -US20040121965A1,6,CCOC(=O)/C(C)=C/[C@@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1)C(C)(C)SCc1ccc(OC)cc1>>COc1ccc(CSC(C)(C)[C@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c2ccccc2)C(=O)N(C)[C@@H](/C=C(\C)C(=O)O)C(C)C)cc1 -US20090143439A1,9,COC(=O)c1cc(OC)cc(N)n1.N>>COc1cc(N)nc(C(N)=O)c1 -US20150110809A1,2,COc1ccc(N)c(OC)n1.Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>COc1ccc(NS(=O)(=O)c2c(C)cc(C)cc2C)c(OC)n1 -US20130345123A1,6,CC(=O)SCC[C@H](NC(=O)OCc1ccccc1)C(=O)NCCCCC=O>>O=CCCCCNC(=O)[C@H](CCS)NC(=O)OCc1ccccc1 -US05137890,6,CC(=O)N1CCc2nc(Nc3ccc(C(F)(F)F)cc3)nc(-c3ccc(Cl)cc3)c2C1>>FC(F)(F)c1ccc(Nc2nc3c(c(-c4ccc(Cl)cc4)n2)CNCC3)cc1 -US20090239848A1,2,O=C(O)CC(=O)Nc1nc(-c2ccccc2)cs1.O=C(c1ccccc1C(F)(F)F)N1CCNCC1>>O=C(CC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)Nc1nc(-c2ccccc2)cs1 -US07642264B2,3,CC(C)(C)NS(=O)(=O)c1cccc(B(O)O)c1.Fc1ccc(-c2cc(C(F)(F)F)nc(-c3ccnc(Cl)c3)n2)cc1F>>CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(F)c(F)c4)cc(C(F)(F)F)n3)ccn2)c1 -US20150191439A1,1,CCSc1ccc(C=O)cc1.NC12CC3CC(CC(C3)C1)C2>>CCSc1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1 -US08324216B2,1,COc1cc(N2CCN(C(=O)Cn3nc(I)c(Cl)c3C)CC2)ccc1Cl.Cc1c[nH]cn1>>COc1cc(N2CCN(C(=O)Cn3nc(-n4cnc(C)c4)c(Cl)c3C)CC2)ccc1Cl -US08044069B2,2,Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1.O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCCC(c2ccccc2)(c2ccccc2)C1=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US20140329863A1,4,CCOC(=O)C(=O)CBr.Cc1ccc(NC(N)=S)nc1>>CCOC(=O)c1csc(Nc2ccc(C)cn2)n1 -US20080269234A1,6,O=C(OCc1ccccc1)N1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1>>O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCCNCC1 -US08552039B2,6,COc1ccccc1C#C[Si](C)(C)C>>C#Cc1ccccc1OC -US20130005744A1,9,COc1cc(Br)c(-c2cccc(-c3ccccc3)c2)nc1OC.[C-]#N>>COc1cc(C#N)c(-c2cccc(-c3ccccc3)c2)nc1OC -US20140011881A1,6,CCCOc1cc(C(F)(F)F)ccc1C=CC(=O)OC>>CCCOc1cc(C(F)(F)F)ccc1C=CC(=O)O -US04500341,6,COC(=O)C(C)(Oc1cccc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)c1)[N+](=O)[O-]>>CC(Oc1cccc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)c1)(C(=O)O)[N+](=O)[O-] -US20150111894A1,6,COc1cc(-n2cnc3oc(-c4ccc(Cl)cc4)cc3c2=O)ccc1O[Si](C)(C)C(C)(C)C>>COc1cc(-n2cnc3oc(-c4ccc(Cl)cc4)cc3c2=O)ccc1O -US20060167023A1,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.Clc1ccc2c(c1)NCCC2>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCCc2ccc(Cl)cc21 -US05093373,1,CC(C)(CO)CCl.ClCc1cccc(Oc2ccccc2)n1>>CC(C)(CCl)COCc1cccc(Oc2ccccc2)n1 -US20110118236A1,1,CC(C)(C)OC(=O)NCCBr.FC(F)(F)c1n[nH]c2c1CCCC2>>CC(C)(C)OC(=O)NCCn1nc(C(F)(F)F)c2c1CCCC2 -US07301032B2,3,CCC1CCCC(I)C1.CSc1nsc(Cl)n1>>CCC1CCCC(c2nc(SC)ns2)C1 -US20040014802A1,7,CCCC(=O)Nc1n[nH]c2c([N+](=O)[O-])c(Br)ccc12>>CCCC(=O)Nc1n[nH]c2c(N)c(Br)ccc12 -US20140275026A1,3,COc1nccc2c(I)c[nH]c12.OB(O)c1ccccc1Oc1ccccc1>>COc1nccc2c(-c3ccccc3Oc3ccccc3)c[nH]c12 -US05629322,9,CC(C)=CCC[C@H](C)[C@@H](C)CN=[N+]=[N-]>>CC(C)=CCC[C@H](C)[C@@H](C)CN -US20150232469A1,3,CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1.Fc1ccccc1Br>>CC(C)(C)OC(=O)N1CCC(C(=O)c2ccccc2F)CC1 -US20080234199A1,6,CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(/C=C/C(=O)OC(C)(C)C)cc1>>CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(/C=C/C(=O)O)cc1 -US08076332B2,1,CN(C)CCN.CS(=O)(=O)OCc1ccc(C(=O)OCc2ccccc2)cc1>>CN(C)CCNCc1ccc(C(=O)OCc2ccccc2)cc1 -US20140171405A1,3,Clc1ccc2c(I)nn(C3CCCCO3)c2n1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2nn(C3CCCCO3)c3nc(Cl)ccc23)cn1 -US20150282482A1,3,C#C[Si](C)(C)C.COC(=O)c1cc2ccc(Br)cc2s1>>COC(=O)c1cc2ccc(C#C[Si](C)(C)C)cc2s1 -US06605744B2,7,CCCCCCCC(=O)c1ccc(CCI)cc1>>CCCCCCCCc1ccc(CCI)cc1 -US20070066624A1,1,CCCCC1CN(C2CCOCC2)C(=O)N1C1CCNCC1.COC(=O)c1ccc(Sc2ccc(C=O)c(C)n2)cc1>>CCCCC1CN(C2CCOCC2)C(=O)N1C1CCN(Cc2ccc(Sc3ccc(C(=O)OC)cc3)nc2C)CC1 -US20110237573A1,3,CC(C)(C)OC(=O)C[Zn+].Fc1cc(-c2ccc(Br)cc2F)ccn1>>CC(C)(C)OC(=O)Cc1ccc(-c2ccnc(F)c2)c(F)c1 -US20060142315A1,1,BrCc1ccccc1.C#CCCCC(=O)O>>C#CCCCC(=O)OCc1ccccc1 -US20090054431A1,8,OCc1ccc(Oc2ccc3[nH]cnc3c2)cc1>>O=Cc1ccc(Oc2ccc3[nH]cnc3c2)cc1 -US20110086882A1,9,CCOC(=O)c1cc(Cl)c(N)c(OC)c1.ICI>>CCOC(=O)c1cc(Cl)c(I)c(OC)c1 -US08338605B2,7,COC(=O)c1ccc(-c2ccccc2)c([N+](=O)[O-])c1>>COC(=O)c1ccc(-c2ccccc2)c(N)c1 -US20080275022A1,7,Cc1ccc(NC(=O)OC(C)(C)C)cc1[N+](=O)[O-]>>Cc1ccc(NC(=O)OC(C)(C)C)cc1N -US20090143354A1,3,C=C[Sn](CCCC)(CCCC)CCCC.O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(Cl)ccc12>>C=Cc1ccc2c(NC(=O)CC3CCCCC3)c(Cl)ccc2n1 -US05086184,2,CC(=O)OCC(=O)OCC(C)(C)c1nnc(N)s1.COc1cccc(OC)c1C(=O)Cl>>COc1cccc(OC)c1C(=O)Nc1nnc(C(C)(C)COC(=O)COC(C)=O)s1 -US20110275586A1,2,O=C(Cl)c1ccccc1.O=C(NCC[C@H](O)C(=O)O)OCc1ccccc1>>O=C(NCC[C@H](OC(=O)c1ccccc1)C(=O)O)OCc1ccccc1 -US06432950B1,1,Cc1sc2nc(-c3ccncc3)nc(Cl)c2c1Cl.NCc1ccc(Cl)c(Cl)c1>>Cc1sc2nc(-c3ccncc3)nc(NCc3ccc(Cl)c(Cl)c3)c2c1Cl -US20130045962A1,2,Cc1nc(NN)c(F)c(N2CCN(C)C[C@@H]2C)n1.O=CN(C[C@@H](CC1CCCC1)C(=O)O)OCc1ccccc1>>Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c(F)c(N2CCN(C)C[C@@H]2C)n1 -US20080076924A1,2,NCc1ccccc1N.O=C(Cl)OCc1ccccc1>>Nc1ccccc1CNC(=O)OCc1ccccc1 -US06476076B1,5,COCCl.COc1cc(C#N)ccc1O>>COCOc1ccc(C#N)cc1OC -US07005443B1,5,CC(N)Cc1n[nH]c2ccc(O)cc12.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>CC(Cc1n[nH]c2ccc(O)cc12)NC(=O)OCC1c2ccccc2-c2ccccc21 -US07893099B2,3,Cc1cc(B(O)O)ccn1.N#CC1(NC(=O)[C@H]2C[C@H](S(=O)(=O)c3ccc(Br)cc3C(F)(F)F)C[C@@H]2OC2CCS(=O)(=O)CC2)CC1>>Cc1cc(-c2ccc(S(=O)(=O)[C@@H]3C[C@H](OC4CCS(=O)(=O)CC4)[C@@H](C(=O)NC4(C#N)CC4)C3)c(C(F)(F)F)c2)ccn1 -US04832736,1,COC(=O)[C@H](C)O.Oc1ccc(Oc2ncc(Cl)cc2F)cc1>>COC(=O)[C@@H](C)Oc1ccc(Oc2ncc(Cl)cc2F)cc1 -US20100173933A1,3,C=CC[Sn](CCCC)(CCCC)CCCC.NC(=O)c1c(F)ccc(OCc2nc3cc(Br)ccc3s2)c1F>>C=CCc1ccc2sc(COc3ccc(F)c(C(N)=O)c3F)nc2c1 -US20120190635A1,6,CC[Si](CC)(CC)OC1CCCCCC(OC(C)=O)CCCCC1>>CC(=O)OC1CCCCCC(O)CCCCC1 -US04547499,1,O=c1[nH]c2ccccc2n1C1CCNCC1.O=c1n(CCCCCl)nc2n1-c1ccccc1OC2>>O=c1n(CCCCN2CCC(n3c(=O)[nH]c4ccccc43)CC2)nc2n1-c1ccccc1OC2 -US08222248B2,2,Cc1ccc(N)cc1C.Cc1cccc(C)c1-c1cc2ccc(C(=O)O)cc2[nH]1>>Cc1ccc(NC(=O)c2ccc3cc(-c4c(C)cccc4C)[nH]c3c2)cc1C -US05025031,2,CC(C)NS(=O)(=O)Cl.Oc1ccccc1>>CC(C)NS(=O)(=O)Oc1ccccc1 -US04529548,2,CC(=O)O[C@H]1C[C@@]2(C)[C@@H](CC[C@@H]2O)[C@@H]2CCC3=CC(=O)C=C[C@]3(C)[C@@]12F.CS(=O)(=O)Cl>>CC(=O)O[C@H]1C[C@@]2(C)[C@@H](CC[C@@H]2OS(C)(=O)=O)[C@@H]2CCC3=CC(=O)C=C[C@]3(C)[C@@]12F -US08034811B2,6,CCOC(=O)CNC(=O)Nc1cc(CNc2ccccc2C(=O)NOCc2ccc(C#N)cc2)ccn1>>N#Cc1ccc(CONC(=O)c2ccccc2NCc2ccnc(NC(=O)NCC(=O)O)c2)cc1 -US20110071175A1,6,COC(=O)Cn1c(C)c(Cc2ccccc2S(=O)(=O)N(C)c2ccccc2)c2cc(F)ccc21>>Cc1c(Cc2ccccc2S(=O)(=O)N(C)c2ccccc2)c2cc(F)ccc2n1CC(=O)O -US20090105266A1,4,Nc1ccccc1N.O=C(O)c1cnc(Nc2ccc(Cl)cc2)c(Cl)c1>>Clc1ccc(Nc2ncc(-c3nc4ccccc4[nH]3)cc2Cl)cc1 -US20040143023A1,9,COc1ccc(C=C(Br)Br)cc1O>>COc1ccc(/C=C\Br)cc1O -US06432950B1,1,Clc1cc2c(Cl)nc(-c3ccno3)nc2s1.NCc1ccc(F)cc1>>Fc1ccc(CNc2nc(-c3ccno3)nc3sc(Cl)cc23)cc1 -US05707991,6,COC(=O)C1CC(C(=O)OC(C)(C)C)N(C(=O)CNC(=O)Nc2ccc(Cl)cc2)C1c1ccccc1>>CC(C)(C)OC(=O)C1CC(C(=O)O)C(c2ccccc2)N1C(=O)CNC(=O)Nc1ccc(Cl)cc1 -US20090239846A1,6,Cc1ccc(C(=O)Nc2ccc(F)cc2)cc1-c1nc(NCCN(C)C(=O)OC(C)(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F>>CNCCNc1nc(-c2cc(C(=O)Nc3ccc(F)cc3)ccc2C)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2 -US03992385,7,CN1CC(CC#N)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21>>CN1CC(CC#N)C[C@@H]2c3cccc4c3C(CN4)C[C@H]21 -US07220753B2,1,Fc1cnc(Cl)nc1.OC[C@H]1CC[C@H]2CNCCN2C1>>OC[C@H]1CC[C@H]2CN(c3ncc(F)cn3)CCN2C1 -US20070254882A1,2,CCN(CC)S(=O)(=O)Cl.CCOC(=O)CNCc1cccc(OCCc2nc(-c3ccc(C)cc3)oc2C)c1>>CCOC(=O)CN(Cc1cccc(OCCc2nc(-c3ccc(C)cc3)oc2C)c1)S(=O)(=O)N(CC)CC -US20140275030A1,3,Cc1cnn(C)c1B1OC(C)(C)C(C)(C)O1.O=c1[nH]c2ccc(Br)c3c2n1C(c1ccccn1)CO3>>Cc1cnn(C)c1-c1ccc2[nH]c(=O)n3c2c1OCC3c1ccccn1 -US06200995B1,2,NCc1ccco1.O=C(O)c1cc([N+](=O)[O-])ccc1F>>O=C(NCc1ccco1)c1cc([N+](=O)[O-])ccc1F -US04591590,2,CS(=O)(=O)Cl.Nc1cccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)n1>>CS(=O)(=O)Nc1cccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)n1 -US04871841,2,NC(=O)N1CCCN(N)C1=O.O=C(O)c1cc(OCc2ccccc2)c(OCc2ccccc2)cn1>>NC(=O)N1CCCN(NC(=O)c2cc(OCc3ccccc3)c(OCc3ccccc3)cn2)C1=O -US20150246922A1,3,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1c2n(c3c(Br)cc(C#N)cc13)CCNC2=O>>Cc1c2n(c3c(-c4ccc(S(C)(=O)=O)cc4)cc(C#N)cc13)CCNC2=O -US20100041891A1,7,COc1ccc(CCNc2nccc(-c3cccc([N+](=O)[O-])c3)n2)cc1OC>>COc1ccc(CCNc2nccc(-c3cccc(N)c3)n2)cc1OC -US04885367,2,CS(=O)(=O)Cl.Nc1ccccc1OC1CCCCC1>>CS(=O)(=O)Nc1ccccc1OC1CCCCC1 -US20110212968A1,1,Cc1ccc(CCN)cc1.O=CC1CC1>>Cc1ccc(CCNCC2CC2)cc1 -US20090042852A1,1,CCOC(=O)c1cnc(Cl)c(Cl)c1N.O=C(NS(=O)(=O)c1ccc(Cl)s1)C1CCNCC1>>CCOC(=O)c1cnc(N2CCC(C(=O)NS(=O)(=O)c3ccc(Cl)s3)CC2)c(Cl)c1N -US20090221555A1,1,CN1C(=O)CCCc2cc(N)ccc21.NC(=O)c1cc(N2CCOCC2)ccc1Nc1nc(Cl)ncc1Cl>>CN1C(=O)CCCc2cc(Nc3ncc(Cl)c(Nc4ccc(N5CCOCC5)cc4C(N)=O)n3)ccc21 -US20120322788A1,7,CCOC(=O)/C=C/C(C)(C)CCCCCOC1CCCCO1>>CCOC(=O)CCC(C)(C)CCCCCOC1CCCCO1 -US20110190280A1,1,FCCBr.O=[N+]([O-])c1ccc(O[C@@H]2CCNC2)nc1>>O=[N+]([O-])c1ccc(O[C@@H]2CCN(CCF)C2)nc1 -US04045438,1,CC(=O)OCC1=C(C(=O)O)N2C(=O)C(N)C2SC1.CCOC(=O)N(C)CCl>>CCOC(=O)N(C)COC(=O)C1=C(COC(C)=O)CSC2C(N)C(=O)N12 -US20070060582A1,1,Clc1ncnc2ccc(I)cc12.OCc1ccccc1>>Ic1ccc2ncnc(OCc3ccccc3)c2c1 -US20120129855A1,2,O=C(COC1CCNCC1)N1CCCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C(COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)CC1)N1CCCC1 -US07759366B2,3,N#Cc1ccc(N)cc1Cl.OB(O)c1ccccc1>>N#Cc1ccc(N)cc1-c1ccccc1 -US08048909B2,2,O=Cc1c[nH]c(-c2ccccc2)c1.O=S(=O)(Cl)c1ccc2ncsc2c1>>O=Cc1cc(-c2ccccc2)n(S(=O)(=O)c2ccc3ncsc3c2)c1 -US06359134B1,6,CCOC(=O)C1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1C(=O)c1sc(-c2ccncc2)nc1C>>Cc1nc(-c2ccncc2)sc1C(=O)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1C(=O)O -US06951879B2,7,CS(=O)(=O)OCCC#Cc1ccc2c(-c3ccc(Cl)cc3)nsc2c1>>CS(=O)(=O)OCCCCc1ccc2c(-c3ccc(Cl)cc3)nsc2c1 -US20080249131A1,7,Cc1ccc2c(C)cc(C)c([N+](=O)[O-])c2n1>>Cc1ccc2c(C)cc(C)c(N)c2n1 -US20060160851A1,1,COC(=O)c1ccc(-c2ccc(O)cc2)cc1.O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(O)CC1>>COC(=O)c1ccc(-c2ccc(OC3CCN(C(=O)Oc4ccc(Oc5ccc(C(F)(F)F)cn5)cc4)CC3)cc2)cc1 -US05455252,3,CSCc1ccc(N)c(Br)c1.OB(O)c1cccc(Cl)c1>>CSCc1ccc(N)c(-c2cccc(Cl)c2)c1 -US20050192286A1,2,CC(C)[C@H](N)c1cccc(F)c1N1CCN(C(=O)C2CN(C(C)C)CC2c2ccc(Cl)cc2Cl)CC1.CN(C)CCC(=O)O>>CC(C)[C@H](NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(C(=O)[C@H]2CN(C(C)C)C[C@@H]2c2ccc(Cl)cc2Cl)CC1 -US05830386,7,CCCCCC[C@H](F)CC(=O)OC>>CCCCCC[C@H](F)CCO -US20080194681A1,10,CC(=O)c1ccc(C)cc1.O=C1CCC(=O)N1Br>>CC(=O)c1ccc(CBr)cc1 -US20100256377A1,3,OB(O)c1ccccc1.Oc1ccc2cc(Br)ccc2c1>>Oc1ccc2cc(-c3ccccc3)ccc2c1 -US05322638,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCC(c2ccc(F)c(F)c2)CC1>>COC=C1CCC(c2ccc(F)c(F)c2)CC1 -US06664259B2,2,Nc1ccc(Cl)c(S(N)(=O)=O)c1O.O=C=NC12CC3CC(CC(C3)C1)C2>>NS(=O)(=O)c1c(Cl)ccc(NC(=O)NC23CC4CC(CC(C4)C2)C3)c1O -US20090253680A1,6,CCOC(=O)CN1CCN(C2CCN(C(=O)[C@@H](Cc3cc(C)c(O)c(C)c3)OC(=O)N3CCC(n4nc(-c5ccccc5)[nH]c4=O)CC3)CC2)CC1>>Cc1cc(C[C@@H](OC(=O)N2CCC(n3nc(-c4ccccc4)[nH]c3=O)CC2)C(=O)N2CCC(N3CCN(CC(=O)O)CC3)CC2)cc(C)c1O -US20060194783A1,9,O=[N+]([O-])c1ccccc1CCBr.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCc1ccccc1[N+](=O)[O-] -US20080161187A1,1,C[O-].N#Cc1ccncc1Cl>>COc1cnccc1C#N -US20100317657A1,3,CC1(C)OB(c2cnc(N)c(F)c2)OC1(C)C.Cc1nn(C)c(C)c1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>Cc1nn(C)c(C)c1-n1c(=O)n(C)c2cnc3ccc(-c4cnc(N)c(F)c4)cc3c21 -US20070203130A1,6,CC(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)c2ccccc12>>Nc1ccc(S(=O)(=O)Nc2nccs2)c2ccccc12 -US20110105436A1,4,Cc1cccc(NC(N)=S)c1.O=C(CBr)c1ccncc1Br>>Cc1cccc(Nc2nc(-c3ccncc3Br)cs2)c1 -US07652015B2,7,CC(C)(C)C(=O)N1CCN(c2cc(Cl)c([N+](=O)[O-])cn2)CC1>>CC(C)(C)C(=O)N1CCN(c2cc(Cl)c(N)cn2)CC1 -US09045436B2,1,BrCCc1ccccc1.COC(=O)c1cc2ccccc2[nH]1>>COC(=O)c1cc2ccccc2n1CCc1ccccc1 -US04124596,1,CC(C(=O)[O-])c1cccc(C(=O)c2cc3ccsc3s2)c1.CCN(CC)CCCl>>CCN(CC)CCOC(=O)C(C)c1cccc(C(=O)c2cc3ccsc3s2)c1 -US20060052398A1,1,Cc1c(Cl)ncnc1NC[C@H](NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C.c1cc2c(nc1C1CCNCC1)NCCC2>>Cc1c(NC[C@H](NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)ncnc1N1CCC(c2ccc3c(n2)NCCC3)CC1 -US08501382B1,2,COC(C)CCO.O=S(=O)(Cl)c1ccccc1C(F)(F)F>>COC(C)CCOS(=O)(=O)c1ccccc1C(F)(F)F -US20150073001A1,2,CC(C)(C)OC(=O)N1CC[C@@H](N)[C@H](O)C1.Cc1cc(-c2ncnc3c(C(=O)O)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)cc1F>>Cc1cc(-c2ncnc3c(C(=O)N[C@@H]4CCN(C(=O)OC(C)(C)C)C[C@H]4O)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)cc1F -US08829026B2,1,COC(=O)c1ccc(S(=O)(=O)NCc2ccc3c(cnn3C)c2)cc1.FC(F)(F)c1cnc(Cl)c(Cl)c1>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc3c(cnn3C)c2)c2ncc(C(F)(F)F)cc2Cl)cc1 -US07026331B2,9,Brc1ccc2c(c1)[nH]c1cnccc12.N#C[Cu]>>N#Cc1ccc2c(c1)[nH]c1cnccc12 -US20030027743A1,2,O=C(Cl)OCc1ccccc1.O=C(O)[C@@H]1Cc2ccccc2N1>>O=C(O)[C@@H]1Cc2ccccc2N1C(=O)OCc1ccccc1 -US20100041892A1,6,CCOC(=O)CCc1cc(OCc2ccccc2)nn1Cc1ccc(Cl)cc1Cl>>O=C(O)CCc1cc(OCc2ccccc2)nn1Cc1ccc(Cl)cc1Cl -US05426187,3,C#C[Si](C)(C)C.CC(C)(C)C(=O)Nc1nc(O)c2c(I)c[nH]c2n1>>CC(C)(C)C(=O)Nc1nc(O)c2c(C#C[Si](C)(C)C)c[nH]c2n1 -US08022222B2,1,Cc1csc(N)n1.Clc1cc(Sc2ccccc2)ccn1>>Cc1csc(Nc2cc(Sc3ccccc3)ccn2)n1 -US08404861B2,2,CC(C)COC(=O)Cl.COC(c1ccc(NC(=O)c2c(C)nn(C)c2C)cc1CC(C)C)(C(F)(F)F)C(F)(F)F>>COC(c1ccc(N(C(=O)OCC(C)C)C(=O)c2c(C)nn(C)c2C)cc1CC(C)C)(C(F)(F)F)C(F)(F)F -US05945548,3,CCOC(=O)CC(=O)OCC.O=Cc1ccccc1>>CCOC(=O)C(=Cc1ccccc1)C(=O)OCC -US07482448B2,2,CCC(N)[C@H](O)c1nc(C2CC2)no1.CCCC(F)(F)C[C@H](NC(=O)N1CCOCC1)C(=O)O>>CCCC(F)(F)CC(NC(=O)N1CCOCC1)C(=O)NC(CC)C(O)c1nc(C2CC2)no1 -US04072696,2,CC(=O)Cl.CCCCSc1ccc(NC(=S)NC(=O)OC)c(N)c1>>CCCCSc1ccc(NC(=S)NC(=O)OC)c(NC(C)=O)c1 -US20140073637A1,1,Cc1cnc(Cl)c2c1[nH]c1ccc3cc(O)ccc3c12.ClCCCN1CCCCC1>>Cc1cnc(Cl)c2c1[nH]c1ccc3cc(OCCCN4CCCCC4)ccc3c12 -US20070293477A1,2,CC(C)(C)OC(=O)N1CCCC(N)CC1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCCC(NC(=O)OCc2ccccc2)CC1 -US20050272036A1,1,O=C(CBr)c1cccs1.O=C(c1ccc(Cl)cc1)C1CCNCC1>>O=C(CN1CCC(C(=O)c2ccc(Cl)cc2)CC1)c1cccs1 -US20150119456A1,6,CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Cc1ccc2c(c1C(=O)OC)OC[C@@H]1C[C@H]21>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Cc1ccc2c(c1C(=O)O)OC[C@@H]1C[C@H]21 -US20040167337A1,1,Brc1cccc(-c2ccccc2)c1.COc1cc(C[C@H](N)C(=O)O)cc(OC)c1OC>>COc1cc(C[C@H](Nc2cccc(-c3ccccc3)c2)C(=O)O)cc(OC)c1OC -US20100222345A1,7,Nc1nc(Br)ccc1[N+](=O)[O-]>>Nc1ccc(Br)nc1N -US06057335,7,C=CCc1ccc(-c2cc(NC(=O)C3Cc4ccccc4C3)n[nH]2)cc1>>CCCc1ccc(-c2cc(NC(=O)C3Cc4ccccc4C3)n[nH]2)cc1 -US07084149B2,3,CC(C)C(O)(c1ccc2cc(Br)ccc2c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.CON(C)C(C)=O>>CC(=O)c1ccc2cc(C(O)(c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)C(C)C)ccc2c1 -US20120277259A1,7,O=[N+]([O-])c1ccc(Cl)c2cnccc12>>Nc1ccc(Cl)c2cnccc12 -US07595314B2,9,CC(=O)c1ccc(N2CCN(C(=O)c3cc(C(=O)O)ccc3N3CCOCC3)CC2)c(F)c1.N>>CC(=O)c1ccc(N2CCN(C(=O)c3cc(C(N)=O)ccc3N3CCOCC3)CC2)c(F)c1 -US20030114524A1,6,CCOC(=O)C(CCCCCCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2CC[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12)CCCC(F)(F)C(F)(F)F>>C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCCCCCC(CCCC(F)(F)C(F)(F)F)C(=O)O)[C@H]3[C@@H]1CC[C@@H]2O -US05248825,1,CNOC.COc1cc(C(=O)Cl)cc(OC)c1OC>>COc1cc(C(=O)N(C)OC)cc(OC)c1OC -US07541365B2,6,CCOC(=O)C(C)(C)Oc1ccc2c(c1)C(=CCCN1CCC(O)(c3ccc(Cl)cc3)C(C)(C)C1)c1cccnc1CO2>>CC(C)(Oc1ccc2c(c1)C(=CCCN1CCC(O)(c3ccc(Cl)cc3)C(C)(C)C1)c1cccnc1CO2)C(=O)O -US05231102,9,COC(=O)Cc1ccc(CC#CCl)cc1.[N-]=[N+]=[N-]>>COC(=O)Cc1ccc(CC#CN=[N+]=[N-])cc1 -US03963718,1,NC1=NCC(c2ccccc2Cl)N1CCCl>>Clc1ccccc1C1CN=C2NCCN21 -US20120077812A1,6,CC(C)c1noc(N2CCC(COc3ccc(-c4ccc(S(=O)(=O)NCCNC(=O)OC(C)(C)C)cc4)cc3)CC2)n1>>CC(C)c1noc(N2CCC(COc3ccc(-c4ccc(S(=O)(=O)NCCN)cc4)cc3)CC2)n1 -US20090215743A1,2,C1CCNCC1.COc1cccc(C2OC(CC(=O)O)c3nnc(CO)n3-c3ccc(Cl)cc32)c1OC>>COc1cccc(C2OC(CC(=O)N3CCCCC3)c3nnc(CO)n3-c3ccc(Cl)cc32)c1OC -US20040044201A1,2,C=CCNCC(C)CC=C.O=S(=O)(Cl)c1ccccn1>>C=CCC(C)CN(CC=C)S(=O)(=O)c1ccccn1 -US20140135270A1,9,C=CCOc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(N)=O)cc1>>C=CCOc1ccc(C[C@@H](C#N)NC(=O)OC(C)(C)C)cc1 -US08501732B2,2,NCc1c(-c2ncco2)n(-c2ccccc2)c2ncccc2c1=O.O=C(O)c1ccc(N2CCOCC2)nc1>>O=C(NCc1c(-c2ncco2)n(-c2ccccc2)c2ncccc2c1=O)c1ccc(N2CCOCC2)nc1 -US20110245249A1,1,Clc1ncc(Cl)c(NC2CC2)n1.Nc1cccc(C2OCCCO2)c1>>Clc1cnc(Nc2cccc(C3OCCCO3)c2)nc1NC1CC1 -US08828991B2,3,COC(=O)c1cc(Br)ccc1N.OB(O)c1ccc(Cl)cc1>>COC(=O)c1cc(-c2ccc(Cl)cc2)ccc1N -US04316022,1,CC(=O)Cl.c1ccc2c(c1)NNc1nncn1-2>>CC(=O)N1Nc2nncn2-c2ccccc21 -US07067534B1,1,COc1ccc(C(O)CCN2CCC(c3cccc(NC(=O)C(C)C)c3)CC2)cc1.Oc1ccc(F)cc1>>COc1ccc(C(CCN2CCC(c3cccc(NC(=O)C(C)C)c3)CC2)Oc2ccc(F)cc2)cc1 -US05798316,7,COC(=O)COc1cc(C)ccc1C=O>>COC(=O)COc1cc(C)ccc1CO -US20150210682A1,2,CCC(N)Cc1ccc(C)c(OCc2ccccc2)c1.O=CO>>CCC(Cc1ccc(C)c(OCc2ccccc2)c1)NC=O -US20090209522A1,7,COc1nc(N2CCCN(C(=O)OC(C)(C)C)CC2)nc(OC)c1[N+](=O)[O-]>>COc1nc(N2CCCN(C(=O)OC(C)(C)C)CC2)nc(OC)c1N -US20050192347A1,6,CCOC(=O)C(C)(C)CCCCN1C(=O)c2ccccc2C1=O>>CCOC(=O)C(C)(C)CCCCN -US04490369,1,COc1cc2c(cc1OC)CC(=O)NC=C2.ClCCBr>>COc1cc2c(cc1OC)CC(=O)N(CCCl)C=C2 -US08314126B2,1,COCCBr.CS(=O)(=O)Oc1cccc(C2CCNCC2)c1F>>COCCN1CCC(c2cccc(OS(C)(=O)=O)c2F)CC1 -US06242474B1,7,CCCCCS(=O)(=O)NC(=O)c1ccc([N+](=O)[O-])c(NCc2ccc(Cl)cc2Cl)c1>>CCCCCS(=O)(=O)NC(=O)c1ccc(N)c(NCc2ccc(Cl)cc2Cl)c1 -US20030055297A1,2,CCCC(C)(OC)C(=O)O.CO>>CCCC(C)(OC)C(=O)OC -US06664260B2,1,ClCc1ccccn1.OCCn1cnc2c(Oc3ccccc3)nc3ccccc3c21>>c1ccc(Oc2nc3ccccc3c3c2ncn3CCOCc2ccccn2)cc1 -US04528392,7,CC(=O)c1ccc(OCc2cccc([N+](=O)[O-])c2)cc1O>>CC(=O)c1ccc(OCc2cccc(N)c2)cc1O -US08063234B2,3,O=Cc1ccc2c(c1)OC(F)(F)O2.[Mg+]C1CC1>>OC(c1ccc2c(c1)OC(F)(F)O2)C1CC1 -US08124610B2,2,Nc1nccs1.O=S(=O)(Cl)c1ccc(Br)cc1F>>O=S(=O)(Nc1nccs1)c1ccc(Br)cc1F -US20090043112A1,1,N[C@@H](Cc1ccccc1Br)C(=O)O>>O=C(O)[C@@H]1Cc2ccccc2N1 -US20100063081A1,1,CC(C)(C)OC(=O)N1CCC(CCCO)CC1.NS(=O)(=O)c1ccc(O)cc1F>>CC(C)(C)OC(=O)N1CCC(CCCOc2ccc(S(N)(=O)=O)c(F)c2)CC1 -US08513415B2,1,COC(=O)CN.O=C(c1ccccc1)c1ccccc1>>COC(=O)CN=C(c1ccccc1)c1ccccc1 -US20060004084A1,3,O=C1Cc2cc(F)ccc2N1.O=C1OC(c2ccccc2)c2cc(CO)ccc21>>O=C1Nc2ccc(F)cc2C1=C1OC(c2ccccc2)c2cc(CO)ccc21 -US20100016401A1,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CN)c1.Cn1c(C(=O)O)cc2ccccc21>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)c2cc3ccccc3n2C)c1 -US04968702,3,COC(=O)c1c(N)c(-c2ccc(I)cc2)nc2ccc(F)cc12.OB(O)c1cccnc1>>COC(=O)c1c(N)c(-c2ccc(-c3cccnc3)cc2)nc2ccc(F)cc12 -US07723329B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1ccc(OCCO)cc1CS(=O)(=O)c1ccccc1>>Cc1ccc(S(=O)(=O)OCCOc2ccc([N+](=O)[O-])c(CS(=O)(=O)c3ccccc3)c2)cc1 -US20100249192A1,1,CCOC(=O)c1ccc(F)cc1.Oc1cc(F)ccc1Br>>CCOC(=O)c1ccc(Oc2cc(F)ccc2Br)cc1 -US07709471B2,1,C#CCN1CCC(=O)N(C)c2cnc(Cl)nc21.COc1cc(C(=O)NC2CCN(C)CC2)ccc1N>>C#CCN1CCC(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc21 -US20060155126A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Br)nc1>>CC(C)(C)OC(=O)Nc1ccc(Br)nc1 -US20080293775A1,2,CS(N)(=O)=O.O=C(O)Cc1cc(Oc2ccc(S(=O)(=O)Cc3ccc(F)cc3)cc2Cl)cc(C(F)(F)F)c1>>CS(=O)(=O)NC(=O)Cc1cc(Oc2ccc(S(=O)(=O)Cc3ccc(F)cc3)cc2Cl)cc(C(F)(F)F)c1 -US08173652B2,9,NO.O=CCP(=O)(c1ccccc1)c1ccccc1>>O=P(C/C=N\O)(c1ccccc1)c1ccccc1 -US05530019,1,CCCCCCCCCBr.O=C(O)c1c[nH]c2ccccc12>>CCCCCCCCCOC(=O)c1c[nH]c2ccccc12 -US20010034352A1,1,CC(C)(C)OC(=O)NC1CCNCC1.O=CCc1coc2ccccc12>>CC(C)(C)OC(=O)NC1CCN(CCc2coc3ccccc23)CC1 -US04927968,5,O=Cc1cccc(OCCCN2C(=O)c3ccccc3C2=O)c1.OCCO>>O=C1c2ccccc2C(=O)N1CCCOc1cccc(C2OCCO2)c1 -US20130331378A1,9,COC(=O)c1cccc(C(O)c2c(C3CCCCC3)nn3cc(OC)ccc23)n1>>COC(=O)c1cccc(Cc2c(C3CCCCC3)nn3cc(OC)ccc23)n1 -US06878708B2,3,CCOc1ccccc1-c1nn2c(C3CCCCCC3)nc(C)c2c(=O)[nH]1.O=C(Br)CBr>>CCOc1ccc(C(=O)CBr)cc1-c1nn2c(C3CCCCCC3)nc(C)c2c(=O)[nH]1 -US07875735B2,6,COc1ccc(C2=Cc3ccc(OCc4ccccc4)cc3OC2)cc1>>COc1ccc(C2=Cc3ccc(O)cc3OC2)cc1 -US20100317657A1,3,COCc1cc(B2OC(C)(C)C(C)(C)O2)cnc1N.Cc1nn(C(C)C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>COCc1cc(-c2ccc3ncc4c(c3c2)n(-c2cn(C(C)C)nc2C)c(=O)n4C)cnc1N -US20100216816A1,7,COC(=O)c1cnc(Cl)cn1>>OCc1cnc(Cl)cn1 -US06713474B2,1,CN1CCNCC1.Nc1ncnc2c1c(-c1ccc(OCc3ccccc3)cc1)cn2C1CCC(=O)CC1>>CN1CCN([C@@H]2CC[C@H](n3cc(-c4ccc(OCc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 -US04091115,7,CNC1C=C(c2ccccc2)c2ccccc2CC1>>CNC1CCc2ccccc2C(c2ccccc2)C1 -US04534979,6,CCCCCCOc1ccc(C=CC(C)=CC=CC(=O)OC)cc1>>CCCCCCOc1ccc(C=CC(C)=CC=CC(=O)O)cc1 -US20100239525A1,1,CN1CCNCC1.CS(=O)(=O)OCCc1ccc(Nc2ncc3c(n2)-c2ccccc2C(c2ccc(Cl)c(Cl)c2)C3)cc1>>CN1CCN(CCc2ccc(Nc3ncc4c(n3)-c3ccccc3C(c3ccc(Cl)c(Cl)c3)C4)cc2)CC1 -US20070161654A1,1,Cc1onc(-c2ccc(Br)cc2)c1-c1c[nH]cn1.O=[N+]([O-])c1ccc(F)cc1>>Cc1onc(-c2ccc(Br)cc2)c1-c1cn(-c2ccc([N+](=O)[O-])cc2)cn1 -US04238344,1,CCCCC(O)C1CC=C(C)CC1C>>CCCCC1OC2(C)CCC1C(C)C2 -US20070135490A1,1,CC1(C)OCc2cc([C@@H]3CN(CCc4cccc(CO)c4)C(=O)O3)ccc2O1.Clc1cccc(Cl)c1CCCBr>>CC1(C)OCc2cc([C@@H]3CN(CCc4cccc(COCCCc5c(Cl)cccc5Cl)c4)C(=O)O3)ccc2O1 -US06013654,1,COc1ccc2nc(CCl)cn2c1.Clc1ccc(N2CCNCC2)c(Cl)c1>>COc1ccc2nc(CN3CCN(c4ccc(Cl)cc4Cl)CC3)cn2c1 -US05670675,2,Cc1ccc(S(=O)(=O)N[C@H](C(=O)NC(Cc2ccccc2)C(O)C(N)Cc2ccccc2)C(C)C)cc1.Cc1ccc(S(=O)(=O)N[C@H](C(=O)O)C(C)C)cc1>>Cc1ccc(S(=O)(=O)N[C@H](C(=O)NC(Cc2ccccc2)C(O)C(Cc2ccccc2)NC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)C(C)C)cc1 -US20090156578A1,2,CCCOc1c(CNC)cccc1OC.O=C(O)C=Cc1cnc2[nH]c(=O)cc(O)c2c1>>CCCOc1c(CN(C)C(=O)C=Cc2cnc3[nH]c(=O)cc(O)c3c2)cccc1OC -US06348602B1,1,COc1ccc(C=O)cc1O.OC1Cc2ccccc2C1>>COc1ccc(C=O)cc1OC1Cc2ccccc2C1 -US20070054924A1,2,CC(C)(C)OC(=O)COc1cc(C(=O)O)ccc1Cl.Cc1c(OC2CCN(C[C@H](O)CN)CC2)ccc(Cl)c1Cl>>Cc1c(OC2CCN(C[C@H](O)CNC(=O)c3ccc(Cl)c(OCC(=O)OC(C)(C)C)c3)CC2)ccc(Cl)c1Cl -US20120077781A1,2,NCCP(=O)(O)O.O=C(Cl)OCc1ccccc1>>O=C(NCCP(=O)(O)O)OCc1ccccc1 -US20050288287A1,1,CC(C)(C)c1ccc(I)c(O)c1.CCI>>CCOc1cc(C(C)(C)C)ccc1I -US04933355,2,CCOC(=O)C(=O)c1csc(N)n1.O=C=Nc1ccc(Cl)c(Cl)c1>>CCOC(=O)C(=O)c1csc(NC(=O)Nc2ccc(Cl)c(Cl)c2)n1 -US08557816B2,1,Brc1ccc2c(Oc3ccc(Nc4nnc(-c5ccccc5)c5ccccc45)cc3)ccnc2c1.C1COCCN1>>c1ccc(-c2nnc(Nc3ccc(Oc4ccnc5cc(N6CCOCC6)ccc45)cc3)c3ccccc23)cc1 -US06093838,6,COc1ccc(N(c2cc3c(c(C(C)(C)C)c2C)OCC3(C)C)C(C)C)cc1>>Cc1c(N(c2ccc(O)cc2)C(C)C)cc2c(c1C(C)(C)C)OCC2(C)C -US06150367,1,Clc1cccc(N2CCNCC2)c1.O=C1CCCN1CCCCl>>O=C1CCCN1CCCN1CCN(c2cccc(Cl)c2)CC1 -US05952342,2,CCCN=C=O.Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(N)nc2n1>>CCCNC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl -US20070254940A1,7,Cc1cc2cc([N+](=O)[O-])ccc2n1CCN1CCCC1>>Cc1cc2cc(N)ccc2n1CCN1CCCC1 -US05296495,1,CC(C)(C)c1csc(-c2cc3cc(CCl)ccc3o2)n1.O=C(O)c1ccccc1S>>CC(C)(C)c1csc(-c2cc3cc(CSc4ccccc4C(=O)O)ccc3o2)n1 -US20140081027A1,6,C=Cc1csc(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>C=Cc1csc(C2CCNCC2)n1 -US20110288090A1,9,COc1nccc2nc(-c3ccc(C(C)(C)N=[N+]=[N-])cc3)c(-c3ccccc3)cc12>>COc1nccc2nc(-c3ccc(C(C)(C)N)cc3)c(-c3ccccc3)cc12 -US07632857B2,2,O=C(O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1.OC[C@@H]1CCCN1>>O=C(c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)N1CCC[C@H]1CO -US05639752,1,CN(C)CCc1c[nH]c2ccc(N)cc12.Clc1ncccn1>>CN(C)CCc1c[nH]c2ccc(Nc3ncccn3)cc12 -US06335344B1,4,NC=O.Nc1cc2c(cc1C(=O)O)OCO2>>O=c1[nH]cnc2cc3c(cc12)OCO3 -US20140155391A1,2,COC(=O)c1ccc(F)c(N)c1.CS(=O)(=O)Cl>>COC(=O)c1ccc(F)c(NS(C)(=O)=O)c1 -US20070259879A1,1,CNC.C[C@@H]1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1ccc(Br)cc1F>>C[C@@H]1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1ccc(Br)cc1N(C)C -US20100120741A1,4,CNc1c(N)cnc2ccc(Cl)cc12.O=CO>>Cn1cnc2cnc3ccc(Cl)cc3c21 -US20070123504A1,2,Cc1oc(C2CCCCC2)cc1C(=O)O.Nc1ccc(N2CCOCC2)nc1>>Cc1oc(C2CCCCC2)cc1C(=O)Nc1ccc(N2CCOCC2)nc1 -US06733123B2,2,C=C(C)C(=O)Cl.NCC(=O)O>>C=C(C)C(=O)NCC(=O)O -US07915411B2,1,O=C(Nc1ccc(F)c([N+](=O)[O-])c1)c1cccc(C(F)(F)F)c1.Oc1ccc(S)cc1>>O=C(Nc1ccc(Sc2ccc(O)cc2)c([N+](=O)[O-])c1)c1cccc(C(F)(F)F)c1 -US07868034B2,1,Clc1ccc2scc(CBr)c2c1.O=C1Nc2ccccc2C1=O>>O=C1C(=O)N(Cc2csc3ccc(Cl)cc23)c2ccccc21 -US20050277662A1,1,COCc1c(C(=O)OC)ncc2[nH]ccc12.Fc1ccc(CBr)c(F)c1>>COCc1c(C(=O)OC)ncc2c1ccn2Cc1ccc(F)cc1F -US20100087424A1,6,CC(C)(C)OC(=O)NC[C@@H]1CN(Cc2ccccc2)CC[C@@H]1O>>CC(C)(C)OC(=O)NC[C@@H]1CNCC[C@@H]1O -US08546404B2,6,CC(C)(C)OC(=O)N1CCC(C#Cc2ccccc2)CC1>>C(#CC1CCNCC1)c1ccccc1 -US09102591B2,2,N#Cc1ccc(C(=O)O)c(F)c1.NCC1(c2ccc(F)nc2)CCC(F)(F)CC1>>N#Cc1ccc(C(=O)NCC2(c3ccc(F)nc3)CCC(F)(F)CC2)c(F)c1 -US20140024650A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@@H]1CC(F)(F)CC[C@@H]1N>>CCOC(=O)[C@@H]1CC(F)(F)CC[C@@H]1NC(=O)OC(C)(C)C -US20100152443A1,1,CC(C)N(C(=O)Cl)C(C)C.Cc1cc(Oc2ncc(C(F)(F)F)cc2Cl)n[nH]1>>Cc1cc(Oc2ncc(C(F)(F)F)cc2Cl)nn1C(=O)N(C(C)C)C(C)C -US04760069,9,CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5.NO>>CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=NO)CC[C@@]3(O)[C@H]1C5 -US05102877,8,C=CCOC(=O)N1CC(C(C)O)CN1C(=O)N(C)C>>C=CCOC(=O)N1CC(C(C)=O)CN1C(=O)N(C)C -US20070082912A1,1,Fc1ccc(CBr)cc1.O=Cc1cc(F)ccc1O>>O=Cc1cc(F)ccc1OCc1ccc(F)cc1 -US05387512,1,CCc1cc(C(=O)OC)c(Cl)nc1C.CO>>CCc1cc(C(=O)OC)c(OC)nc1C -US20120202806A1,1,CCNCC.Fc1ccccc1Cc1cnc(-c2ccccn2)nc1Cl>>CCN(CC)c1nc(-c2ccccn2)ncc1Cc1ccccc1F -US20120289540A1,8,CSc1ncc(CO)c(NC(C)C)n1>>CSc1ncc(C=O)c(NC(C)C)n1 -US08013156B2,1,CC(C)(C)OC(=O)N1CCCNCC1.Clc1nsnc1Cl>>CC(C)(C)OC(=O)N1CCCN(c2nsnc2Cl)CC1 -US20120035239A1,9,CCC(C(N)=O)N1CC(C=C(Br)Br)CC1=O>>C#CC1CC(=O)N(C(CC)C(N)=O)C1 -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)[C@@H](C)OC>>CO[C@H](C)[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)O -US06608078B2,7,CCCC1CN(Cc2ccccc2)CCC1=O>>CCCC1CN(Cc2ccccc2)CCC1O -US20010012857A1,1,BrCCC=C(c1ccccc1)c1ccccc1.CCOC(=O)CN>>CCOC(=O)CNCCC=C(c1ccccc1)c1ccccc1 -US20080119547A1,7,O=C1CC(c2ccc3c(c2)OCO3)c2ccccc21>>O[C@@H]1C[C@H](c2ccc3c(c2)OCO3)c2ccccc21 -US07268152B2,3,COc1ccc(F)cc1C(C)(C)CC(=O)C(F)(F)F.[Mg+]Cc1ccccc1>>COc1ccc(F)cc1C(C)(C)CC(O)(Cc1ccccc1)C(F)(F)F -US20060148856A1,1,O=[N+]([O-])c1cc(C2CCCCC2)ccc1Nc1cccc(Br)c1.c1cc[nH]c1>>O=[N+]([O-])c1cc(C2CCCCC2)ccc1Nc1cccc(-n2cccc2)c1 -US20120046292A1,1,CCOC(=O)[C@@H]1CC[C@@H](O)CC1.O=C(NCCNC(=O)c1ccc(O)cc1F)c1ccc(Cl)cc1>>CCOC(=O)[C@@H]1CC[C@H](Oc2ccc(C(=O)NCCNC(=O)c3ccc(Cl)cc3)c(F)c2)CC1 -US04791216,1,BrCCCCCCBr.O=C(NCCc1ccccc1)C(F)(F)F>>O=C(N(CCCCCCBr)CCc1ccccc1)C(F)(F)F -US20130090323A1,3,COc1ccc(B(O)O)c(C)n1.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1Br>>COc1ccc(-c2cnc(N3CCOCC3)cc2Nc2c(C)c(-c3ccccn3)nc3cc(F)cc(F)c23)c(C)n1 -US06469017B1,7,C[C@@H](O)CCCCn1c(=O)c2c(ncn2C)n(CCCCCC#N)c1=O>>C[C@@H](O)CCCCn1c(=O)c2c(ncn2C)n(CCCCCCN)c1=O -US20060223826A1,2,COC(=O)[C@H](N)[C@@H](C)c1c[nH]c2ccccc12.O=C(O)C1CCN(C(=O)c2ccccc2)CC1>>COC(=O)[C@H](NC(=O)C1CCN(C(=O)c2ccccc2)CC1)[C@@H](C)c1c[nH]c2ccccc12 -US20050137401A1,9,COC(=O)[C@H](c1ccccc1Cl)N1Cc2ccsc2C(O)C1>>COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1 -US06271265B1,2,CC(=O)Cl.CC(C)(C)NC(=O)c1ccc2[nH]ccc2c1>>CC(=O)n1ccc2cc(C(=O)NC(C)(C)C)ccc21 -US20030229096A1,3,COc1ccc2cccc(B3OC(C)(C)C(C)(C)O3)c2c1.Cc1nccn1Cc1cc(Cl)cnn1>>COc1ccc2cccc(-c3cnnc(Cn4ccnc4C)c3)c2c1 -US20080318953A1,1,C[O-].O=[N+]([O-])c1c(Cl)cc(N2CCOCC2)nc1Cl>>COc1nc(N2CCOCC2)cc(Cl)c1[N+](=O)[O-] -US20120115841A1,5,CCOC(=O)c1coc(C(C)=O)n1.OCCO>>CCOC(=O)c1coc(C2(C)OCCO2)n1 -US20140371220A1,3,CNC(=O)c1ccc(B(O)O)cn1.Fc1ccc2c(c1)N(C1CCN(c3ccc(Cl)nn3)CC1)CC2>>CNC(=O)c1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 -US20090143361A1,3,COc1ccc2nc(Cl)c3c(C)nc(CCC(F)(F)F)n3c2n1.C[Mg+]>>COc1ccc2nc(C)c3c(C)nc(CCC(F)(F)F)n3c2n1 -US04273711,1,NNc1ccccc1.O=C1CCCC(=O)C1>>O=C1CCCC(=NNc2ccccc2)C1 -US20040034035A1,3,O=Cc1ccccc1.[Mg+]c1ccccc1>>OC(c1ccccc1)c1ccccc1 -US04983607,7,COC(=O)CC1CC(=O)Nc2ccccc21>>O=C1CC(CCO)c2ccccc2N1 -US08802864B2,3,CC1(C)OB(c2ccc3occc3c2)OC1(C)C.O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(Br)cc2)C1>>O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(-c3ccc4occc4c3)cc2)C1 -US20060057144A1,1,BrCc1cccc(Br)c1.Oc1cccc(Br)c1>>Brc1cccc(COc2cccc(Br)c2)c1 -US20080009462A1,6,C=CCCCCCCCCCCCCCCOCc1ccccc1>>C=CCCCCCCCCCCCCCCO -US08669271B2,3,CC(C)(C)OC(=O)N1CCC(C2Cc3cc(Cl)ncc3O2)CC1.OB(O)c1ccnc(F)c1>>CC(C)(C)OC(=O)N1CCC(C2Cc3cc(-c4ccnc(F)c4)ncc3O2)CC1 -US20110319380A1,4,NC=O.Nc1cc(Br)cnc1C(=O)O>>O=c1[nH]cnc2cc(Br)cnc12 -US07968575B2,2,Cc1nc(N)sc1CCO[N+](=O)[O-].O=C(O)CCCCC1CCSS1>>Cc1nc(NC(=O)CCCCC2CCSS2)sc1CCO[N+](=O)[O-] -US20100120801A1,1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)c[nH]2)CC1.CN(C)CCCl>>CN(C)CCn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(C(=O)OC(C)(C)C)CC1 -US20140315801A1,3,CCCC[Sn](CCCC)(CCCC)c1cc2nccc(Cl)c2s1.O=C1OCCCN1Cc1ccc(Br)nc1>>O=C1OCCCN1Cc1ccc(-c2cc3nccc(Cl)c3s2)nc1 -US20150191439A1,1,CC(=O)c1ccc(C)s1.NC12CC3CC(CC(C3)C1)C2>>Cc1ccc(C(C)NC23CC4CC(CC(C4)C2)C3)s1 -US20150225396A1,2,Cn1c(=O)n(C2CCNCC2)c2ccc(Cl)cc21.O=C(O)CCCc1nc2ccccc2c(=O)[nH]1>>Cn1c(=O)n(C2CCN(C(=O)CCCc3nc4ccccc4c(=O)[nH]3)CC2)c2ccc(Cl)cc21 -US20150284367A1,1,COc1ccc(Nc2cc(Cl)nnc2C(N)=O)nc1C(C)C.NCCN>>COc1ccc(Nc2cc(NCCN)nnc2C(N)=O)nc1C(C)C -US04738968,2,CS(=O)(=O)Cl.OCC1CN(Cc2ccccc2)CC1O>>CS(=O)(=O)OCC1CN(Cc2ccccc2)CC1O -US06987114B1,1,CC(=O)CCl.Cc1cc(C)cc(Oc2[nH]c(=O)[nH]c(=O)c2C(C)C)c1>>CC(=O)Cn1c(Oc2cc(C)cc(C)c2)c(C(C)C)c(=O)[nH]c1=O -US20070010526A1,2,CC(C)c1ccc(CC(=O)O)cc1.COc1ccc(Br)c2c1CCNC2>>COc1ccc(Br)c2c1CCN(C(=O)Cc1ccc(C(C)C)cc1)C2 -US06284785B1,2,FC(F)(F)c1ccc(C2CCCN2)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)N1CCCC1c1ccc(C(F)(F)F)cc1 -US08557872B2,1,CCCCI.COC(=O)C=Cc1ccc(F)cc1O>>CCCCOc1cc(F)ccc1C=CC(=O)OC -US20090118284A1,7,CC(C)(C)OC(=O)n1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc([N+](=O)[O-])cc23)cn1>>CC(C)(C)OC(=O)n1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc(N)cc23)cn1 -US20100035871A1,1,CCI.[N-]=[N+]=NCC1CNc2cccc(-c3ccccc3Cl)c2O1>>CCN1CC(CN=[N+]=[N-])Oc2c(-c3ccccc3Cl)cccc21 -US20080004325A1,6,COC(=O)CN(c1csc(-c2cccc(NC3CCCCC3)c2)c1C)S(=O)(=O)NC(=O)OC(C)(C)C>>COC(=O)CN(c1csc(-c2cccc(NC3CCCCC3)c2)c1C)S(N)(=O)=O -US07196081B2,3,C=CCc1c(OS(=O)(=O)C(F)(F)F)ccc2cc(OC)ccc12.COc1ccc(B(O)O)cc1>>C=CCc1c(-c2ccc(OC)cc2)ccc2cc(OC)ccc12 -US08012979B2,1,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(C=O)c2c1.OCCN1CCCNCC1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CN3CCCN(CCO)CC3)c2c1 -US20140288042A1,7,Cc1c(Br)cccc1C(=O)O>>Cc1c(Br)cccc1CO -US07618980B2,3,CC(C)(C)OC(=O)Nc1ccccc1C(F)(F)F.CN(C)C=O>>CC(C)(C)OC(=O)Nc1c(C=O)cccc1C(F)(F)F -US05059597,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CO[C@H]1CN(Cc2ccccc2)C[C@H]1N>>CO[C@H]1CN(Cc2ccccc2)C[C@H]1NC(=O)OC(C)(C)C -US20070142389A1,1,CC(C)(C)OC(=O)N1CC[C@@H](c2ccccc2)[C@H](COS(C)(=O)=O)C1.COc1cc(C#N)ccc1O>>COc1cc(C#N)ccc1OC[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1c1ccccc1 -US08063099B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c1.O=C(O)c1ccc2ccccc2n1>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2ccc3ccccc3n2)c1 -US20030018193A1,6,C=CCN(CCC(=O)OCC)C(=O)OC(C)(C)C>>C=CCN(CCC(=O)O)C(=O)OC(C)(C)C -US20070254931A1,6,CC(=O)Nc1nc(CCc2ccc(NCCNC(=O)OC(C)(C)C)cc2)cs1>>CC(=O)Nc1nc(CCc2ccc(NCCN)cc2)cs1 -US06777407B2,1,NC(=O)CCl.c1ccc2c(c1)NC1CCCC21>>NC(=O)CN1c2ccccc2C2CCCC21 -US06107301,7,Cc1cc(C)c([N+](=O)[O-])c(C)n1>>Cc1cc(C)c(N)c(C)n1 -US05951914,2,CC(=O)Oc1ccc(C(=O)O)c(F)c1.CCCC(C)O>>CCCC(C)OC(=O)c1ccc(OC(C)=O)cc1F -US08552200B2,1,C1COCCN1.COC(=O)c1c(C)cc(Cl)nc1OC>>COC(=O)c1c(C)cc(N2CCOCC2)nc1OC -US20140018533A1,1,CCOC(=O)C1=C(N(C)CCO)OCC1=O.COCCOCCl>>CCOC(=O)C1=C(N(C)CCOCOCCOC)OCC1=O -US20050137243A1,2,Nc1ccc2cnn(CCN3CCCC3)c2c1.O=C(O)CCSc1ccc2ccccc2c1>>O=C(CCSc1ccc2ccccc2c1)Nc1ccc2cnn(CCN3CCCC3)c2c1 -US07402596B2,7,O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cccc2c(=O)n(Cc3ccccc3)ccc12>>O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cccc2c1CCN(Cc1ccccc1)C2=O -US06514968B1,1,BrCCOc1cccc2c1c1ccccc1n2Cc1ccccc1.NCc1ccccn1>>c1ccc(Cn2c3ccccc3c3c(OCCNCc4ccccn4)cccc32)cc1 -US07432293B2,1,CNCC(C)C.O=C(O)c1cccc(-c2cc(-c3ccc(Cl)nc3)on2)c1>>CC(C)CN(C)c1ccc(-c2cc(-c3cccc(C(=O)O)c3)no2)cn1 -US20030187023A1,2,CC(=O)OC(C)=O.CNCCN(C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccnc(C)c2)CC1>>CC(=O)N(C)CCN(C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccnc(C)c2)CC1 -US07737166B2,1,Cc1c(C#N)c(N)c(OC(=O)C2=CCCC2)c(F)c1-c1ccccc1>>Cc1c(-c2ccccc2)c(F)c2oc(C3=CCCC3)nc2c1C#N -US07560558B2,8,CCC(O)c1cccc(F)c1Oc1ccnc2cc(OC)c(OC)cc12>>CCC(=O)c1cccc(F)c1Oc1ccnc2cc(OC)c(OC)cc12 -US20120157433A1,1,CC(C)(C)[S@@](N)=O.O=CC1CCOCC1>>CC(C)(C)[S@](=O)/N=C/C1CCOCC1 -US20080319188A1,1,Nc1cc(Cl)ccn1.O=[N+]([O-])c1ccc(O)c(F)c1>>Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ccn1 -US05616579,1,Nc1cc(N)nc(S)n1.O=C(CCCCl)NC/C=C\COc1cc(CN2CCCCC2)ccn1>>Nc1cc(N)nc(SCCCC(=O)NC/C=C\COc2cc(CN3CCCCC3)ccn2)n1 -US07456194B2,2,CC(C)(N=C=O)c1cccc(Br)c1.OCc1ccccc1>>CC(C)(NC(=O)OCc1ccccc1)c1cccc(Br)c1 -US20090278088A1,9,CCCC1(O)CCC(C2CCC(COc3ccc(OCC)c(F)c3F)CC2)CO1>>CCCC1CCC(C2CCC(COc3ccc(OCC)c(F)c3F)CC2)CO1 -US20150018328A1,1,COc1ccc(CN)cc1.C[C@@H](Nc1nc(N[C@H](C)C2CC2)nc(-c2cccc(Cl)n2)n1)C1CC1>>COc1ccc(CNc2cccc(-c3nc(N[C@H](C)C4CC4)nc(N[C@H](C)C4CC4)n3)n2)cc1 -US06800651B2,1,COC(=O)c1ccc(N)cc1.O=Cc1cccnc1>>COC(=O)c1ccc(NCc2cccnc2)cc1 -US20130005707A1,5,Brc1ccc2c(c1)CNC2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1Cc2ccc(Br)cc2C1 -US08697737B2,8,CC(C)[Si](C(C)C)(C(C)C)n1ncc2cc(C(O)c3ccccc3C#N)ccc21>>CC(C)[Si](C(C)C)(C(C)C)n1ncc2cc(C(=O)c3ccccc3C#N)ccc21 -US06506775B1,1,CC(C)(C)OC(=O)N1CCCC(N)C1c1ccccc1.COc1ccc(C(C)(C)C#CC(F)(F)F)cc1C=O>>COc1ccc(C(C)(C)C#CC(F)(F)F)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1 -US05652363,7,COc1ncccc1[N+](=O)[O-]>>COc1ncccc1N -US20120134987A1,3,COC(=O)c1cccc(Br)n1.OB(O)c1c(F)ccc(OCc2ccccc2)c1F>>COC(=O)c1cccc(-c2c(F)ccc(OCc3ccccc3)c2F)n1 -US04613607,7,O=C(CCC1CCNCC1)c1cc(-c2ccccc2)nc2ccccc12>>OC(CCC1CCNCC1)c1cc(-c2ccccc2)nc2ccccc12 -US20140170110A1,1,COc1ncccc1N.N#CSc1nc(Cl)ncc1[N+](=O)[O-]>>COc1ncccc1Nc1ncc([N+](=O)[O-])c(SC#N)n1 -US20150225367A1,2,CS(=O)(=O)Cl.Nc1ccc(-c2c[nH]c3cc(F)ccc23)cn1>>CS(=O)(=O)Nc1ccc(-c2c[nH]c3cc(F)ccc23)cn1 -US04921855,1,CN(CC=O)C(=O)OC(C)(C)C.COC(=O)CN>>COC(=O)CNCCN(C)C(=O)OC(C)(C)C -US08592475B2,6,Cn1ncc(Cl)c1-c1cc(NC(=O)[C@H](CNC(=O)OCc2ccccc2)Cc2ccc(F)c(F)c2)sc1Cl>>Cn1ncc(Cl)c1-c1cc(NC(=O)[C@H](CN)Cc2ccc(F)c(F)c2)sc1Cl -US20070225292A1,2,CN=C=O.Nc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCOCC2)c2ccccc12>>CNC(=O)Nc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCOCC2)c2ccccc12 -US20040006081A1,1,BrCCC(c1ccccc1)c1ccccc1.CC(C)(C)OC(=O)NC1CCNCC1>>CC(C)(C)OC(=O)NC1CCN(CCC(c2ccccc2)c2ccccc2)CC1 -US20060160851A1,2,O=C(Cl)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1.c1cc(OC2CCNCC2)ccc1Cc1nnn[nH]1>>O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(Oc2ccc(Cc3nnn[nH]3)cc2)CC1 -US20070244125A1,1,BrCC1CC1.O=C(c1ccc2[nH]c(C(=O)N3CCS(=O)(=O)CC3)cc2c1)N1CCN(C2CCCC2)CC1>>O=C(c1ccc2c(c1)cc(C(=O)N1CCS(=O)(=O)CC1)n2CC1CC1)N1CCN(C2CCCC2)CC1 -US05929097,3,C#CCCCCCCCCCC.COC(=O)c1cc(Br)cc(C)c1N(C)S(=O)(=O)c1ccc(OC)cc1>>CCCCCCCCCCC#Cc1cc(C)c(N(C)S(=O)(=O)c2ccc(OC)cc2)c(C(=O)OC)c1 -US06569890B2,4,CCOC(=O)C(CC(=O)c1ccccc1)C(C)=O.Nc1cccc(Br)c1>>CCOC(=O)c1cc(-c2ccccc2)n(-c2cccc(Br)c2)c1C -US08969587B2,7,CC(C)(C#N)c1cccc([N+](=O)[O-])c1>>CC(C)(C#N)c1cccc(N)c1 -US20090054398A1,2,COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(Sc1ccccc1N)c1cc(F)ccc1F>>O=C(N[C@@H]1C(=O)Nc2ccccc2S[C@H]1c1cc(F)ccc1F)OCc1ccccc1 -US04021479,7,Cc1cc(Cl)ccc1-c1ccc(C(=O)CCC(=O)O)cc1>>Cc1cc(Cl)ccc1-c1ccc(CCCC(=O)O)cc1 -US08324252B2,1,N#Cc1c(Cl)nc(Cl)c(F)c1I.Nc1cc(C2CC2)[nH]n1>>N#Cc1c(Cl)nc(Nc2cc(C3CC3)[nH]n2)c(F)c1I -US06069145,1,CC(C)(C)OC(=O)N1CCNC(=O)C1.CI>>CN1CCN(C(=O)OC(C)(C)C)CC1=O -US06982348B2,1,C=C(C)CCl.Cc1ccc(O)c(Br)c1>>C=C(C)COc1ccc(C)cc1Br -US20140371201A1,1,COc1cc(-c2ccc(Cl)c(C)c2)c(F)cc1Nc1ccc(Br)cc1C=O.SCc1ccccc1>>COc1cc(-c2ccc(Cl)c(C)c2)c(F)cc1Nc1ccc(SCc2ccccc2)cc1C=O -US08143274B2,1,CI.O=c1[nH]c(-c2ccccc2N2CCNCC2)cc2ccc(N3CCCC(O)C3)cc12>>CN1CCN(c2ccccc2-c2cc3ccc(N4CCCC(O)C4)cc3c(=O)[nH]2)CC1 -US20150133402A1,7,COc1ccc(COc2cccc(C=O)c2Br)cc1>>COc1ccc(COc2cccc(CO)c2Br)cc1 -US20080214607A1,6,c1ccc(COc2ccc(-n3cncc3-c3ccncc3)cc2)cc1>>Oc1ccc(-n2cncc2-c2ccncc2)cc1 -US20140378459A1,1,BrCc1ccccc1.O=C(O)c1cc2ccc(O)cc2[nH]1>>O=C(OCc1ccccc1)c1cc2ccc(O)cc2[nH]1 -US07199119B2,7,COC(=O)c1ccc(Br)c(O)c1>>OCc1ccc(Br)c(O)c1 -US07645781B2,7,Cn1c(=O)oc2cc([N+](=O)[O-])cc(F)c21>>Cn1c(=O)oc2cc(N)cc(F)c21 -US20070287838A1,2,Nc1ccc(Oc2ccnc(N)c2[N+](=O)[O-])c(Cl)c1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>Nc1nccc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2Cl)c1[N+](=O)[O-] -US20030008842A1,2,CC(C)(C)C(=O)NN.CC1(C)O[C@@H]2[C@@H](C(=O)O)O[C@@H](n3cnc4c(Cl)ncnc43)[C@@H]2O1>>CC1(C)O[C@@H]2[C@@H](C(=O)NNC(=O)C(C)(C)C)O[C@@H](n3cnc4c(Cl)ncnc43)[C@@H]2O1 -US20090286835A1,4,C[C@]12CC(C=O)C(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@@]21OCOC12COCO2.NNc1cc(F)cc(F)c1>>C[C@]12Cc3cnn(-c4cc(F)cc(F)c4)c3C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@@]21OCOC12COCO2 -US20110245241A1,6,CCOC(=O)c1nc(C2CCCC2)n(C)c(=O)c1OCc1ccccc1>>Cn1c(C2CCCC2)nc(C(=O)O)c(OCc2ccccc2)c1=O -US20140057953A1,2,CNc1ccccc1F.O=C(Cl)c1ccc(Br)s1>>CN(C(=O)c1ccc(Br)s1)c1ccccc1F -US05591762,6,CCCc1nc2c(C)cc(-c3cn(CCc4ccccc4)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCc1nc2c(C)cc(-c3cn(CCc4ccccc4)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US07750049B2,6,COc1cc(CNC(C)=O)c(Br)cc1OC(C)=O>>COc1cc(CNC(C)=O)c(Br)cc1O -US20140378459A1,1,CC(C)(C)OC(=O)CBr.CC(C)(C)OC(=O)Cc1ccc(CN)cc1>>CC(C)(C)OC(=O)CNCc1ccc(CC(=O)OC(C)(C)C)cc1 -US20030236258A1,4,COc1ccc(C(=O)CC(=O)C(F)(F)F)cc1C.CS(=O)(=O)c1ccc(NN)nc1>>COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)cc1C -US20090088419A1,7,CCc1nc(CC(C)(C)C)c(C#N)c(-c2ccc(C)cc2)c1C(=O)OC>>CCc1nc(CC(C)(C)C)c(CN)c(-c2ccc(C)cc2)c1C(=O)OC -US20150284409A1,1,OCCCc1c(O)nc(Cl)c2ccccc12>>Clc1nc2c(c3ccccc13)CCCO2 -US08546376B2,6,COc1ccc2oc(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(=O)c2c1>>COc1ccc2oc(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)c(=O)c2c1 -US20040058956A1,6,OCCc1nccn1CCCc1ccc(OCc2ccccc2)cc1>>OCCc1nccn1CCCc1ccc(O)cc1 -US20100179211A1,6,Fc1cccc(C2(F)CCN(Cc3ccccc3)C2)c1F>>Fc1cccc(C2(F)CCNC2)c1F -US08901156B2,2,NCCc1coc(-c2ccc(Cl)cc2)n1.O=C(O)c1cncc(-c2noc(C(F)(F)F)n2)c1>>O=C(NCCc1coc(-c2ccc(Cl)cc2)n1)c1cncc(-c2noc(C(F)(F)F)n2)c1 -US04186199,7,CC1=Nc2ccccc2N2CCc3cccc1c32>>CC1Nc2ccccc2N2CCc3cccc1c32 -US20100227870A1,2,N#Cc1cc(F)ccc1N1CCNCC1.O=C(O)CCOc1ccccc1>>N#Cc1cc(F)ccc1N1CCN(C(=O)CCOc2ccccc2)CC1 -US08470828B2,2,N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1.O=C(O)c1ccc(C(F)(F)F)cc1>>O=C(N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1)c1ccc(C(F)(F)F)cc1 -US20070078262A1,8,C[C@H](CO)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](OC(=O)c2ccccc2)C(C)(C)C1CC3>>C[C@H](C=O)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](OC(=O)c2ccccc2)C(C)(C)C1CC3 -US20100016396A1,1,CCI.Cc1nn(C)c(Oc2cc(O[C@@H](C)C(=O)O)c(Cl)cc2Cl)c1C>>CCOC(=O)[C@H](C)Oc1cc(Oc2c(C)c(C)nn2C)c(Cl)cc1Cl -US05006549,1,C=CCBr.Cc1coc2c(C(=O)c3cccs3)ccc(O)c12>>C=CCOc1ccc(C(=O)c2cccs2)c2occ(C)c12 -US04399134,7,Cc1cc2c(N3CCOCC3)c(F)ccc2[nH]1>>CC1Cc2c(ccc(F)c2N2CCOCC2)N1 -US20110257014A1,1,COC(=O)Cc1c(C)n[nH]c1-c1ccc(Cl)cc1.Cn1cncc1I>>COC(=O)Cc1c(C)nn(-c2cncn2C)c1-c1ccc(Cl)cc1 -US20090124596A1,2,Cc1cc(C(=O)O)nn1C.N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(CN5CCC(N6CCCCC6)CC5)cc4)c3)c2=O)CC1>>Cc1cc(C(=O)N[C@@H]2CC[C@H](n3c(=O)c4cc(F)cnc4n(-c4cccc(-c5ccc(CN6CCC(N7CCCCC7)CC6)cc5)c4)c3=O)CC2)nn1C -US20090298899A1,2,CCOC(=O)c1cc2cc(N)ccc2o1.O=C(O)c1ccc(-c2ccccc2)o1>>CCOC(=O)c1cc2cc(NC(=O)c3ccc(-c4ccccc4)o3)ccc2o1 -US07544703B2,6,CC(=O)Nc1cc(COC(C)=O)ccn1>>CC(=O)Nc1cc(CO)ccn1 -US20100063066A1,1,CC(=O)n1ncc2c(N)cccc21.O=S(=O)(Oc1c(-c2ncccn2)oc2cnccc12)C(F)(F)F>>CC(=O)n1ncc2c(Nc3c(-c4ncccn4)oc4cnccc34)cccc21 -US05312829,1,CC(C)Cc1ccc(C(Cc2cccc(C(=O)c3c[nH]c4ccccc34)c2)c2ccc(CC(C)C)cc2)cc1.CCOC(=O)CCCBr>>CCOC(=O)CCCn1cc(C(=O)c2cccc(CC(c3ccc(CC(C)C)cc3)c3ccc(CC(C)C)cc3)c2)c2ccccc21 -US06013654,1,BrCc1ccccc1.OCc1c(CN2CCN(c3ccc(Cl)cc3Cl)CC2)nc2ccc(Cl)cn12>>Clc1ccc(N2CCN(Cc3nc4ccc(Cl)cn4c3COCc3ccccc3)CC2)c(Cl)c1 -US20140005168A1,6,Cc1cncc(-c2cc3c(cn2)cnn3-c2cc(N3CCC[C@H](NC(=O)OC(C)(C)C)C3)c(=O)n(C)c2)n1>>Cc1cncc(-c2cc3c(cn2)cnn3-c2cc(N3CCC[C@H](N)C3)c(=O)n(C)c2)n1 -US20030144326A1,1,NC[C@H](O)c1ccc2nnnn2c1.O=C1CCN(c2ccc(CC3SC(=O)NC3=O)cc2)CC1>>O=C1NC(=O)C(Cc2ccc(N3CCC(NC[C@H](O)c4ccc5nnnn5c4)CC3)cc2)S1 -US08778939B2,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C(Nc1cccnc1)c1cc(Br)ccc1OCc1ccc(F)cc1>>Cn1cc(-c2ccc(OCc3ccc(F)cc3)c(C(=O)Nc3cccnc3)c2)cn1 -US06284785B1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Fc1ccc([C@@H]2CCCN2)cc1>>Cc1ccc(S(=O)(=O)N2CCC[C@H]2c2ccc(F)cc2)cc1 -US04908371,6,CCOCCCn1ccc(=O)c(OCc2ccccc2)c1C>>CCOCCCn1ccc(=O)c(O)c1C -US09040522B2,2,C1COCCN1.Cc1c(-c2cnn(-c3ccc(C(=O)O)cn3)c2O)ccc(C#N)c1F>>Cc1c(-c2cnn(-c3ccc(C(=O)N4CCOCC4)cn3)c2O)ccc(C#N)c1F -US20120149721A1,1,CCOC(=O)c1c(C)[nH]c2c(-c3cc(C)c(F)cc3OCC3CC3)ncnc12.C[Si](C)(C)CCOCCl>>CCOC(=O)c1c(C)n(COCC[Si](C)(C)C)c2c(-c3cc(C)c(F)cc3OCC3CC3)ncnc12 -US06136823,1,C#Cc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c12.CN>>C#Cc1c(NC)c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c12 -US20120035122A1,2,CS(=O)(=O)Cl.FC(F)(F)c1cc(Cl)cc(C2(C(F)(F)F)CC(c3ccc(C4(F)CNC4)cc3)=NO2)c1>>CS(=O)(=O)N1CC(F)(c2ccc(C3=NOC(c4cc(Cl)cc(C(F)(F)F)c4)(C(F)(F)F)C3)cc2)C1 -US20110230665A1,7,CCOC(=O)[C@@H]1C[C@@H](C(C)C)[C@H](c2ccc(OC)c(OCCCOC)c2)N1C(=O)OC(C)(C)C>>COCCCOc1cc([C@H]2[C@H](C(C)C)C[C@@H](CO)N2C(=O)OC(C)(C)C)ccc1OC -US08946260B2,1,Cc1ccncc1I.O=C1NCCc2ccc(Cl)c(F)c21>>Cc1ccncc1N1CCc2ccc(Cl)c(F)c2C1=O -US07544701B2,7,CN(C)CCNc1ccccc1[N+](=O)[O-]>>CN(C)CCNc1ccccc1N -US08765940B2,1,Cc1c(-c2cccnc2)nc2cc(F)ccc2c1Cl.c1cc2c(cc1N1CCOCC1)NCC21CCOCC1>>Cc1c(-c2cccnc2)nc2cc(F)ccc2c1N1CC2(CCOCC2)c2ccc(N3CCOCC3)cc21 -US20130261130A1,3,COC(=O)c1ccc([N+](=O)[O-])cc1Br.OB(O)c1ccc(Cl)cc1>>COC(=O)c1ccc([N+](=O)[O-])cc1-c1ccc(Cl)cc1 -US05650428,2,CCOC(=O)Cc1ccc(N)cc1.O=C(O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc(Cl)cc1>>CCOC(=O)Cc1ccc(NC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)cc1 -US20150274700A2,1,CC(=O)N[C@H]1CCNC1.CCCc1cc(Cl)nc(Cl)n1>>CCCc1cc(N2CC[C@H](NC(C)=O)C2)nc(Cl)n1 -US20110245249A1,5,O=Cc1cccc(Nc2ncc(Cl)c(NC3CC3)n2)c1.OCCO>>Clc1cnc(Nc2cccc(C3OCCO3)c2)nc1NC1CC1 -US06897231B2,3,COc1ccc(B(O)O)cc1.N#Cc1ccc2c(c1)c(Br)nn2C1CCCCO1>>COc1ccc(-c2nn(C3CCCCO3)c3ccc(C#N)cc23)cc1 -US04945098,2,C=C(CO)COC(=O)CCCCCBr.CCCCCCCCCCCCCN=C=O>>C=C(COC(=O)CCCCCBr)COC(=O)NCCCCCCCCCCCCC -US20150232445A1,1,CI.COC(=O)N1c2ccc(-c3csc(C4(O)CN(C(=O)OC(C)(C)C)C4)n3)c(OC3CCC3)c2CC[C@@H]1C>>COC(=O)N1c2ccc(-c3csc(C4(OC)CN(C(=O)OC(C)(C)C)C4)n3)c(OC3CCC3)c2CC[C@@H]1C -US05457106,1,O=C1c2ccccc2C(=O)N1CCCBr.Oc1ccncc1>>O=C1c2ccccc2C(=O)N1CCCOc1ccncc1 -US04018794,7,CCCCOc1cc(C(=O)O)cc([N+](=O)[O-])c1C(=O)c1ccccc1>>CCCCOc1cc(C(=O)O)cc(N)c1C(=O)c1ccccc1 -US20020193402A1,6,Cn1nnc([C@]2(F)C[C@@]3(c4ccccc4)[C@H](OCc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC[C@@H]2N3Cc2ccccc2)n1>>Cn1nnc([C@]2(F)C[C@]3(c4ccccc4)N[C@H]2CC[C@H]3OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1 -US20080119456A1,4,COC(=O)CC(Br)C(=O)c1ccc(F)cc1.N=C(N)C(c1ccccc1)c1ccccc1>>COC(=O)Cc1[nH]c(C(c2ccccc2)c2ccccc2)nc1-c1ccc(F)cc1 -US20030144326A1,1,NC[C@H](O)COc1ccc(O)cc1.O=C1CCN(c2ccc(CC3SC(=O)NC3=O)cc2)CC1>>O=C1NC(=O)C(Cc2ccc(N3CCC(NC[C@H](O)COc4ccc(O)cc4)CC3)cc2)S1 -US05866577,1,COC(=O)C(=O)c1ccc(O)cc1.OC1CCOC1>>COC(=O)C(=O)c1ccc(OC2CCOC2)cc1 -US20110105491A1,4,CC(N)=S.COC(=O)C(=O)C(Cl)c1ccc(C)c(F)c1F>>COC(=O)c1nc(C)sc1-c1ccc(C)c(F)c1F -US04806145,6,COc1cc(-n2nc(C)n(C(F)F)c2=O)c(Br)cc1Br>>Cc1nn(-c2cc(O)c(Br)cc2Br)c(=O)n1C(F)F -US09156840B2,6,COC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(C(=O)OC(C)(C)C)CC3)C2=O)c1>>CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(Cc1cccc(C(=O)O)c1)CN2c1ccccc1 -US05550240,1,C1CCNC1.Clc1cc(Cl)nc(NC2CCCC2)n1>>Clc1cc(N2CCCC2)nc(NC2CCCC2)n1 -US05864039,3,O=C(Cl)CCCCCCCBr.c1ccccc1>>O=C(CCCCCCCBr)c1ccccc1 -US08088936B2,3,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(OCC)c2)c1CCC(=O)OCC.OB(O)c1cccc(F)c1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(OCC)cc(-c3cccc(F)c3)c2)c1CCC(=O)OCC -US20110212892A1,1,C=CCBr.Cc1ccc(C(=O)c2ccc[nH]2)cc1>>C=CCn1cccc1C(=O)c1ccc(C)cc1 -US20110201656A1,10,COc1ccc(-c2nnn(-c3ccc(C(F)(F)F)cc3Cl)c2C)cc1.O=C1CCC(=O)N1Br>>COc1ccc(-c2nnn(-c3ccc(C(F)(F)F)cc3Cl)c2CBr)cc1 -US20150239847A1,2,Nc1ccn(-c2cccc(F)c2F)n1.O=C(Cl)c1ccccc1Br>>O=C(Nc1ccn(-c2cccc(F)c2F)n1)c1ccccc1Br -US20120245344A1,1,CC(C)(C)OC(=O)N1CCC(c2ccc(CO)nc2)CC1.Cc1cc([N+](=O)[O-])cc2cc[nH]c12>>Cc1cc([N+](=O)[O-])cc2ccn(Cc3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cn3)c12 -US06630495B1,2,NCc1ncc(C(F)(F)F)cc1Cl.O=C(Cl)c1ccco1>>O=C(NCc1ncc(C(F)(F)F)cc1Cl)c1ccco1 -US07067534B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.CS(=O)(=O)Cl>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](NS(C)(=O)=O)c3ccccc3)CC2)c1 -US20060135576A1,1,CN1CCNCC1.O=C(NC1CC1)c1cc(NCc2cnc(Nc3cccc(Br)n3)s2)c(F)cc1F>>CN1CCN(c2cccc(Nc3ncc(CNc4cc(C(=O)NC5CC5)c(F)cc4F)s3)n2)CC1 -US07071231B2,2,CC(=O)Nc1ccc2ccc(S(=O)(=O)Cl)cc2c1.Nc1ccc(Cl)c(C(=O)O)c1>>CC(=O)Nc1ccc2ccc(S(=O)(=O)Nc3ccc(Cl)c(C(=O)O)c3)cc2c1 -US20070185136A1,4,COc1ccc(S(=O)(=O)N(CC#N)c2ccc(Cl)cc2C(=O)c2ccccc2Cl)cc1OC.C[Si](C)(C)N=[N+]=[N-]>>COc1ccc(S(=O)(=O)N(Cc2nnn[nH]2)c2ccc(Cl)cc2C(=O)c2ccccc2Cl)cc1OC -US04127606,1,CCCCN.CN(C)CCCOc1ccccc1C=O>>CCCCN=Cc1ccccc1OCCCN(C)C -US20080171743A1,6,C[C@H]1COCCN1c1cc(CS(C)(=O)=O)nc(-c2ccc(NC(=O)OC(C)(C)C)cc2)n1>>C[C@H]1COCCN1c1cc(CS(C)(=O)=O)nc(-c2ccc(N)cc2)n1 -US20070010511A1,1,COCCCCl.O=C1COc2ccc(CO)cc2N1>>COCCCN1C(=O)COc2ccc(CO)cc21 -US20080033028A1,4,CCOC(=O)CC1CCCCC1=O.NNc1ccc(F)cc1Br>>CCOC(=O)CC1CCCc2c1[nH]c1c(Br)cc(F)cc21 -US20070082912A1,6,CCOC(=O)c1ccnc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(OC)cc2)c1>>COc1ccc(COc2ccc(Cl)cc2-c2ccc(C)n2-c2cc(C(=O)O)ccn2)cc1 -US08178533B2,7,CCOC(=O)c1cc(C(F)(F)F)nc2c1ncn2Cc1ccc(OC)cc1>>COc1ccc(Cn2cnc3c(CO)cc(C(F)(F)F)nc32)cc1 -US20100160323A1,2,O=C(O)CNC(=O)c1cc(-c2ccccc2O)[nH]n1.O=C(c1cc(F)c(F)c(F)c1)N1CCNCC1>>O=C(NCC(=O)N1CCN(C(=O)c2cc(F)c(F)c(F)c2)CC1)c1cc(-c2ccccc2O)[nH]n1 -US04432971,2,CCOC(=O)CNC.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CCOC(=O)CN(C)C(=O)[C@H](C)NC(=O)OC(C)(C)C -US20120129811A1,2,COc1ccc(C(N)=O)cc1N=C=S.Cn1ncc2c(N)cccc21>>COc1ccc(C(N)=O)cc1NC(=S)Nc1cccc2c1cnn2C -US20150266856A1,3,CC(=O)CC(C)=O.CC(C)(C)OC(=O)N1CCC(C=O)CC1>>CC(=O)C(=CC1CCN(C(=O)OC(C)(C)C)CC1)C(C)=O -US08466181B2,2,Cn1nnc(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)O)cn2)cn1.NC1CCOCC1>>Cn1nnc(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)NC3CCOCC3)cn2)cn1 -US20140315881A1,10,COC(=O)Cc1ccc2oc(Br)cc2c1.O=C1CCC(=O)N1Br>>COC(=O)C(Br)c1ccc2oc(Br)cc2c1 -US06762180B1,1,CC(C)S(=O)(=O)NCCN(C)C.O=[N+]([O-])c1ccc(F)cc1>>CC(C)S(=O)(=O)N(CCN(C)C)c1ccc([N+](=O)[O-])cc1 -US20140275129A1,2,COc1ccc2c(c1O)CCNC2.O=C(O)c1nc(-c2ccc(F)cc2)nc2ccccc12>>COc1ccc2c(c1O)CCN(C(=O)c1nc(-c3ccc(F)cc3)nc3ccccc13)C2 -US20040121995A1,3,C=C[Sn](CCCC)(CCCC)CCCC.O=S(=O)(NC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)C(F)(F)F>>C=Cc1ccc(S(=O)(=O)C2(c3cc(F)ccc3F)CCC(NS(=O)(=O)C(F)(F)F)CC2)cc1 -US08084604B2,2,COc1ccc(C(F)(F)F)cc1N=C=O.Nc1c(F)cccc1Br>>COc1ccc(C(F)(F)F)cc1NC(=O)Nc1c(F)cccc1Br -US07851473B2,6,CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccccc3)ns2)CC1>>c1ccc(-c2nsc(N3CCNCC3)n2)cc1 -US08841455B2,1,CN1CCN(CCO)CC1.Cn1cccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(F)ccn45)cccc32)c1=O>>CN1CCN(CCOc2ccn3c(C(=O)Nc4cccc5c4c(C4CC4)nn5Cc4cccn(C)c4=O)cnc3c2)CC1 -US20150210720A1,7,CS(=O)(=O)NCCn1cc2cc([N+](=O)[O-])ccc2n1>>CS(=O)(=O)NCCn1cc2cc(N)ccc2n1 -US05968930,7,COc1cc(C(=O)N2Cc3cccn3Cc3ccccc32)ccc1[N+](=O)[O-]>>COc1cc(C(=O)N2Cc3cccn3Cc3ccccc32)ccc1N -US20100216802A1,1,CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O.OC1CCCC1>>CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC1CCCC1 -US20150133453A1,2,CCOC(=O)c1cc(F)cn1N.O=C(Cl)c1ccc(Br)cc1>>CCOC(=O)c1cc(F)cn1NC(=O)c1ccc(Br)cc1 -US20030158205A1,3,C[Mg+].O=CCC1CN(C(=O)COc2ccc(Cl)cc2)CCN1Cc1ccc(F)cc1>>CC(O)CC1CN(C(=O)COc2ccc(Cl)cc2)CCN1Cc1ccc(F)cc1 -US06204293B1,3,OB(O)c1ccccc1.OCc1ccc(Br)o1>>OCc1ccc(-c2ccccc2)o1 -US20130046013A1,6,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCSC(CC)(CC)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccc(O)c(C(=O)OC)c1>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCSC(CC)(CC)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccc(O)c(C(=O)O)c1 -US20060100213A1,2,C#CC[C@H]1Nc2cccnc2NC1=O.Cc1ccc(S(=O)(=O)Cl)cc1>>C#CC[C@@H]1C(=O)Nc2ncccc2N1S(=O)(=O)c1ccc(C)cc1 -US08436001B2,7,O=[N+]([O-])c1cnn(CC(F)F)c1>>Nc1cnn(CC(F)F)c1 -US09139589B2,9,Cc1nn2ccc(OCc3ccccc3)cc2c1C(N)=O>>Cc1nn2ccc(OCc3ccccc3)cc2c1C#N -US20040242455A1,2,CC(C)c1ccc(CCNS(=O)(=O)c2cc(C#N)ccc2O)c(NCC(=O)O)c1.CCOC(=O)CCN>>CCOC(=O)CCNC(=O)CNc1cc(C(C)C)ccc1CCNS(=O)(=O)c1cc(C#N)ccc1O -US05773612,2,CNC1(c2ccccc2Cl)C(=O)Nc2ccc(Cl)cc21.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CNC1(c2ccccc2Cl)C(=O)N(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)c2ccc(Cl)cc21 -US20140088076A1,1,NC(=O)C1CC1.OC1(c2ccc3cc(Cl)ncc3n2)CCCC1>>O=C(Nc1cc2ccc(C3(O)CCCC3)nc2cn1)C1CC1 -US05650428,1,COC(=O)CCCCCCNC(=O)C(COS(C)(=O)=O)NS(=O)(=O)c1ccc(Cl)cc1.c1c[nH]cn1>>COC(=O)CCCCCCNC(=O)C(Cn1ccnc1)NS(=O)(=O)c1ccc(Cl)cc1 -US04349684,1,COC(=O)CCCCCCCBr.COc1ccc(-n2c(-c3ccccc3)c[nH]c2=O)cc1>>COC(=O)CCCCCCCn1cc(-c2ccccc2)n(-c2ccc(OC)cc2)c1=O -US20130045986A1,3,CC(C)(C)OC(=O)N1CCC(c2nc3cc(B4OC(C)(C)C(C)(C)O4)ccc3o2)CC1.Fc1cc(-n2cnnn2)ccc1Br>>CC(C)(C)OC(=O)N1CCC(c2nc3cc(-c4ccc(-n5cnnn5)cc4F)ccc3o2)CC1 -US20090118305A1,3,CC1(C)OB(c2cnc(N)c(-c3nc4ncccc4o3)c2)OC1(C)C.COc1cc(N2CCN(C)CC2)ccc1Br>>COc1cc(N2CCN(C)CC2)ccc1-c1cnc(N)c(-c2nc3ncccc3o2)c1 -US20090088451A1,1,COc1ccccc1CNc1ccc2cc(Br)ccc2n1.Nc1ncccn1>>COc1ccccc1CNc1ccc2cc(Nc3ncccn3)ccc2n1 -US20140142074A1,1,CN.COc1ccc(CBr)cc1[N+](=O)[O-]>>CNCc1ccc(OC)c([N+](=O)[O-])c1 -US07598393B2,1,CC(C)(C)S.CC(C)(C)c1nc2cc(CCl)ccc2n1CC1CCOCC1>>CC(C)(C)SCc1ccc2c(c1)nc(C(C)(C)C)n2CC1CCOCC1 -US08124649B2,3,CC(=O)c1ccc(-c2ccc(C(=O)N3CCCN(C)CC3)cc2)o1.O=C1Cc2cc(Cl)ccc2N1>>CC(=C1C(=O)Nc2ccc(Cl)cc21)c1ccc(-c2ccc(C(=O)N3CCCN(C)CC3)cc2)o1 -US07727979B2,2,N=C(N)Nc1nc2c(s1)CNCC2.O=C=Nc1ccccc1>>N=C(N)Nc1nc2c(s1)CN(C(=O)Nc1ccccc1)CC2 -US06316468B1,1,C=O.c1ccc(-c2[nH]c3ccccc3c2C2CCNCC2)cc1>>CN1CCC(c2c(-c3ccccc3)[nH]c3ccccc23)CC1 -US20100331293A1,2,Cc1c(N2CCNCC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1.O=S(=O)(Cl)c1cccnc1>>Cc1c(N2CCN(S(=O)(=O)c3cccnc3)CC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1 -US20050283006A1,6,CS[C@H]1C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OCc2ccccc2)C1>>CS[C@H]1C[C@@H](CO)N(C(=O)OCc2ccccc2)C1 -US20090124618A1,1,CN(c1ccc([C@H]2CNCCO2)cc1)C1CCCCC1.Cn1c(Cl)nc(-c2ccncc2)cc1=O>>CN(c1ccc([C@H]2CN(c3nc(-c4ccncc4)cc(=O)n3C)CCO2)cc1)C1CCCCC1 -US04469869,1,CCN(CC)CCCCl.c1ccc2c(C3CCNCC3)noc2c1>>CCN(CC)CCCN1CCC(c2noc3ccccc23)CC1 -US08569535B2,6,CCOC(=O)C1(NC(=O)c2ccccc2S(C)=O)Cc2ccccc2C1>>CS(=O)c1ccccc1C(=O)NC1(C(=O)O)Cc2ccccc2C1 -US08513239B2,2,CCCCN.CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)O)CC1>>CCCCNC(=O)CC1CCN(C(=O)N2C(c3cnc(C(C)(C)C)cc3OCC)=N[C@@](C)(c3ccc(Cl)cc3)[C@@]2(C)c2ccc(Cl)cc2)CC1 -US07521457B2,6,CC(C)(C)OC(=O)NC1CC(OCc2ccccc2)C1>>CC(C)(C)OC(=O)NC1CC(O)C1 -US06713645B1,1,COC(=O)CBr.NC(=O)c1cccc2c1c1c(O)cccc1n2Cc1cccc(C(F)(F)F)c1>>COC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1cccc(C(F)(F)F)c1 -US20080176857A1,2,CCc1cc2c(N3CCNCC3)nc(SCC(=O)OC)nc2s1.CN(C)c1cc(C(=O)O)nc(N(C)C)n1>>CCc1cc2c(N3CCN(C(=O)c4cc(N(C)C)nc(N(C)C)n4)CC3)nc(SCC(=O)OC)nc2s1 -US20080167351A1,3,CC(C)S(=O)(=O)N[C@@H]1C[C@H]1c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cc1cncc(Br)c1>>Cc1cncc(-c2ccc([C@@H]3C[C@H]3NS(=O)(=O)C(C)C)cc2)c1 -US08048893B2,3,Brc1cn(CCN2CCCCC2)nc1OCc1ccccc1.OB(O)c1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(-c2cn(CCN3CCCCC3)nc2OCc2ccccc2)c1 -US06610692B1,9,ClCc1ccc2[nH]nnc2c1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc2[nH]nnc2c1 -US08586584B2,6,COC(=O)c1ccc(Nc2nc(NCCCOCCCCOCCCN)nc(OCC(F)(F)F)n2)cc1>>NCCCOCCCCOCCCNc1nc(Nc2ccc(C(=O)O)cc2)nc(OCC(F)(F)F)n1 -US20150183802A1,7,COC(=O)/C=C/Cc1ccc(F)c(Br)c1>>COC(=O)CCCc1ccc(F)c(Br)c1 -US20150166564A1,6,COCCN1C[C@@H](NC(=O)Nc2c(C)c(OCCN3C(=O)c4ccccc4C3=O)nn2-c2ccccc2)[C@H](c2ccc(F)c(F)c2)C1>>COCCN1C[C@@H](NC(=O)Nc2c(C)c(OCCN)nn2-c2ccccc2)[C@H](c2ccc(F)c(F)c2)C1 -US05869492,8,Clc1ccc(SCC#CCOc2ccccc2)cc1.O=C(OO)c1cccc(Cl)c1>>O=S(CC#CCOc1ccccc1)c1ccc(Cl)cc1 -US20050277670A1,2,CSc1ccc(NC2CCN([C@H](C)CC#N)CC2)cc1.Cc1ccncc1C(=O)O>>CSc1ccc(N(C(=O)c2cnccc2C)C2CCN([C@H](C)CC#N)CC2)cc1 -US05010195,9,COc1nc(C)nc(Cl)c1Cl.NN>>COc1nc(C)nc(NN)c1Cl -US06403610B1,6,COC(=O)[C@H]1CN(CCSc2cccc(F)c2)CC[C@H]1CCCc1ccnc2ccc(OC)cc12>>COc1ccc2nccc(CCC[C@@H]3CCN(CCSc4cccc(F)c4)C[C@@H]3C(=O)O)c2c1 -US20120021016A1,1,CCOC(=O)CBr.Cc1ccc(N2C(=O)NC(=O)C23CCCCC3)cc1>>CCOC(=O)CN1C(=O)N(c2ccc(C)cc2)C2(CCCCC2)C1=O -US03969374,7,O=C1c2ccc([N+](=O)[O-])cc2C(=O)c2c1cccc2[N+](=O)[O-]>>Nc1cccc2c1C(=O)c1cc([N+](=O)[O-])ccc1C2=O -US06828314B2,7,O=C1Cc2[nH]c3cc(F)ccc3c2CCN1>>Fc1ccc2c3c([nH]c2c1)CCNCC3 -US07875602B2,6,CCOC(=O)C(C)ON=C(C)C>>CC(C)=NOC(C)C(=O)O -US20070088040A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.NCC1CCCN1>>c1ccc(C(NCC2CCCN2)(c2ccccc2)c2ccccc2)cc1 -US07205297B2,3,C#Cc1ccc(Cl)cc1.CC(C)N(C=Nc1ncc(I)c(Cl)n1)C(C)C>>CC(C)N(C=Nc1ncc(C#Cc2ccc(Cl)cc2)c(Cl)n1)C(C)C -US20120214803A1,3,COc1ccc([Mg+])cc1F.O=Cc1ccc2cccnc2c1[N+](=O)[O-]>>COc1ccc(C(O)c2ccc3cccnc3c2[N+](=O)[O-])cc1F -US20120289522A1,1,CC=O.CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CNC[C@H](C)c4ccccc4)cc3)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CN(CC)C[C@H](C)c4ccccc4)cc3)cc2)CC1 -US20130102593A1,1,COC(=O)c1cc(Br)cc(C(=O)OC)c1.FC1(F)CCNCC1>>COC(=O)c1cc(C(=O)OC)cc(N2CCC(F)(F)CC2)c1 -US20020103203A1,1,COc1cc(/C=C/c2cc(CCl)[nH]n2)ccc1O.Nc1cccc(C(=O)O)c1>>COc1cc(/C=C/c2cc(CNc3cccc(C(=O)O)c3)[nH]n2)ccc1O -US20150011528A1,7,CCOC(=O)c1ccc2nc(N)sc2c1>>Nc1nc2ccc(CO)cc2s1 -US20150265625A1,7,CC(C)(C#N)c1ccccc1>>CC(C)(CN)c1ccccc1 -US20130116243A1,6,CC(C)(C)OC(=O)NCc1ccc(-c2nc3c(cc2-c2ccccc2)N(CC(F)(F)F)C(=O)CO3)cc1>>NCc1ccc(-c2nc3c(cc2-c2ccccc2)N(CC(F)(F)F)C(=O)CO3)cc1 -US20050245563A1,3,CC[Mg+].CON(C)C(=O)c1c(O)c2cc(Cl)ccc2[nH]c1=O>>CCC(=O)c1c(O)c2cc(Cl)ccc2[nH]c1=O -US20070276019A1,2,CC[C@H](N)C(O)c1nc2ccccc2o1.O=C(O)[C@H](Cc1ccccc1Cl)NC(c1ccccc1)C(F)(F)F>>CC[C@H](NC(=O)[C@H](Cc1ccccc1Cl)NC(c1ccccc1)C(F)(F)F)C(O)c1nc2ccccc2o1 -US07928105B2,1,N#Cc1ccc(N2CCNCC2)cc1.O=C1Nc2cc(CO)cnc2N2CCCC[C@@H]12>>N#Cc1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCCN43)CC2)cc1 -US20090275566A1,3,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cccc(Br)c2)C[C@@H](CO)S1.OB(O)c1cncnc1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cccc(-c3cncnc3)c2)C[C@@H](CO)S1 -US20120101022A1,2,CO.O=C(O)Cc1cccs1>>COC(=O)Cc1cccs1 -US04021564,2,CC(=O)Cl.O=C(c1cccc(C(F)(F)F)c1)C1CCNCC1>>CC(=O)N1CCC(C(=O)c2cccc(C(F)(F)F)c2)CC1 -US05739326,2,NNc1cccc(C(F)(F)F)n1.O=C(Cl)c1ccc(F)cc1>>O=C(NNc1cccc(C(F)(F)F)n1)c1ccc(F)cc1 -US05232917,2,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.Cc1ccc(S(=O)(=O)Cl)cc1>>CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](OS(=O)(=O)c5ccc(C)cc5)CC[C@]4(C)[C@H]3CC[C@]12C -US05486525,2,CSc1ccc(-c2c[nH]c3ccccc23)cc1.O=S(=O)(Cl)c1ccccc1>>CSc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)cc1 -US09085583B2,6,COC(=O)c1cnn(C(C)c2ccccc2)c1C>>Cc1c(C(=O)O)cnn1C(C)c1ccccc1 -US04004011,1,CCCCOc1ccc(N)cn1.CN1CC(=O)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21>>CCCCOc1ccc(NC2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)cn1 -US06005116,1,CC(C)(C)OC(=O)NCCO.Oc1noc(-c2ccccc2)c1C1C=CCC1>>CC(C)(C)OC(=O)NCCOc1noc(-c2ccccc2)c1C1C=CCC1 -US04939241,6,CC(=O)CC(=O)OC[C@H](NC(=O)C(F)(F)F)C(=O)OCc1ccccc1>>CC(=O)CC(=O)OC[C@H](NC(=O)C(F)(F)F)C(=O)O -US20140249131A1,7,COc1cc(N2CCN(C)CC2)ncc1[N+](=O)[O-]>>COc1cc(N2CCN(C)CC2)ncc1N -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)NCc2ccccc2)cc1F.FC(F)(F)c1cnc(Cl)c(Cl)c1>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1F -US20150105373A1,3,CC[Mg+].CON(C)C(=O)c1ccc(OC(F)(F)F)cc1>>CCC(=O)c1ccc(OC(F)(F)F)cc1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCC1.Cc1cc2cc(O)ccc2[nH]1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCCCN1CCCC1 -US20120010182A1,1,C=O.O=S(=O)(Nc1nncs1)c1cc(Cl)c(Oc2ccc(-c3ccccc3C(F)(F)F)cc2-c2ccnn2C2CNC2)cc1F>>CN1CC(n2nccc2-c2cc(-c3ccccc3C(F)(F)F)ccc2Oc2cc(F)c(S(=O)(=O)Nc3nncs3)cc2Cl)C1 -US06974870B2,1,CSc1cc(=O)[nH]c(S)c1C#N.NC(=O)CBr>>CSc1cc(=O)[nH]c(SCC(N)=O)c1C#N -US20150045359A1,6,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(-n3cnc(-c4ccc(F)cc4)n3)cc2)C1>>Fc1ccc(-c2ncn(-c3ccc([C@H]4CNCCO4)cc3)n2)cc1 -US04182769,2,CCOC(=O)Cl.FC(F)C(F)(F)Sc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>CCOC(=O)n1c(SC(F)(F)C(F)F)nc(-c2ccccc2)c1-c1ccccc1 -US20130029942A1,9,COc1ccc(N(C)c2nc(CCl)nc3ccccc23)cc1Cl.O=C1NC(=O)c2ccccc21>>COc1ccc(N(C)c2nc(CN)nc3ccccc23)cc1Cl -US20130090323A1,1,Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl.O=S1(=O)CCCN1>>Cc1c(N2CCCS2(=O)=O)nc2cc(F)cc(F)c2c1Cl -US08586614B2,6,CCOC(=O)CSc1cnc(NC(=O)N(CC2CCCC2)c2c(F)cc(F)cc2F)s1>>O=C(O)CSc1cnc(NC(=O)N(CC2CCCC2)c2c(F)cc(F)cc2F)s1 -US20150232428A1,3,O=[N+]([O-])c1cc(F)cc(I)c1.OB(O)c1ccc([C@H](O)C(F)F)cc1>>O=[N+]([O-])c1cc(F)cc(-c2ccc([C@H](O)C(F)F)cc2)c1 -US20130085277A1,9,CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1>>CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O -US20080287479A1,1,CNC(=O)c1ccc2c(c1)CC(=O)N2C1CCNCC1.O=C(CCl)N1C[C@@H]2CCC[C@@H]2C1>>CNC(=O)c1ccc2c(c1)CC(=O)N2C1CCN(CC(=O)N2C[C@@H]3CCC[C@@H]3C2)CC1 -US08252935B2,1,BrCc1ccccc1.CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C(F)(F)F)N2)c1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C(F)(F)F)N2Cc2ccccc2)c1 -US05948793,1,CI.CN1C(=O)C(CO)C[C@H]1COc1cccnc1>>COCC1C[C@@H](COc2cccnc2)N(C)C1=O -US08809320B2,6,COC(=O)c1cc(NC(=O)c2cc([N+](=O)[O-])cn2C)cn1C>>Cn1cc(NC(=O)c2cc([N+](=O)[O-])cn2C)cc1C(=O)O -US20080194535A1,6,C=CCOC[C@@H](CC(C)C)NC(=O)C(F)(F)F>>C=CCOC[C@H](N)CC(C)C -US07538131B2,1,C1=COCCC1.CC(C)OC(=O)[C@@H]1CCC[C@H](CO)C1>>CC(C)OC(=O)[C@@H]1CCC[C@H](COC2CCCCO2)C1 -US20090023708A1,1,COC(=O)C1CC(=O)N(c2ccc(O)cc2)C1.ClCCCBr>>COC(=O)C1CC(=O)N(c2ccc(OCCCCl)cc2)C1 -US08278325B2,2,CC(C)(C)OC[C@@H](N)C(=O)OC(C)(C)C.O=C(O)c1nc(Cl)c2ccccc2c1O>>CC(C)(C)OC[C@@H](NC(=O)c1nc(Cl)c2ccccc2c1O)C(=O)OC(C)(C)C -US08906889B2,3,C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CCOC(=O)CC1CC=C(B2OC(C)(C)C(C)(C)O2)CC1>>C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(CC(=O)OCC)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US06020362,6,CCCCCNN=Cc1ccc(C(=O)Nc2ccc3c(c2)CCC(CC(=O)OCC)O3)cc1>>CCCCCNN=Cc1ccc(C(=O)Nc2ccc3c(c2)CCC(CC(=O)O)O3)cc1 -US05599811,1,COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1.ClCc1ccc2c(c1)OCO2>>COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1Cc1ccc2c(c1)OCO2 -US20150158865A1,2,COc1ccc(C(=O)O)cc1.N#Cc1ncc(N2CCC[C@@H](N)C2)nc1Cl>>COc1ccc(C(=O)N[C@@H]2CCCN(c3cnc(C#N)c(Cl)n3)C2)cc1 -US06548496B2,2,CC#CC(=O)O.N#Cc1cnc2ncc(N)cc2c1Nc1cccc(Br)c1>>CC#CC(=O)Nc1cnc2ncc(C#N)c(Nc3cccc(Br)c3)c2c1 -US20040220234A1,7,CCOC(=O)C[C@@H](O)C(F)(F)F>>OCC[C@@H](O)C(F)(F)F -US20110182850A1,2,C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)O.CCCC1(S(N)(=O)=O)CC1>>C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)NS(=O)(=O)C1(CCC)CC1 -US04479942,6,C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H]1[C@@H](C(=O)O)O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@@H]1O>>C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H]1[C@@H](C(=O)O)O[C@@H](n2cnc3c(N)ncnc32)[C@@H]1O -US20110077399A1,6,CCn1cc(-c2ccc(Cl)cc2Cl)nc1/C=C/c1ccc2cc(OCc3ccccc3)ccc2c1>>CCn1cc(-c2ccc(Cl)cc2Cl)nc1/C=C/c1ccc2cc(O)ccc2c1 -US20030166658A1,1,CC(=O)c1ccc(C)cn1.Cn1c(NN)nc2ccccc21>>CC(=NNc1nc2ccccc2n1C)c1ccc(C)cn1 -US20110136800A1,2,COc1ccc(Oc2ccc3c(c2)CC[C@@H]2NCCC[C@H]32)cc1.O=C(O)c1ccc2[nH]cnc2c1>>COc1ccc(Oc2ccc3c(c2)CC[C@H]2[C@@H]3CCCN2C(=O)c2ccc3[nH]cnc3c2)cc1 -US20090093479A1,6,COc1cc(Br)cc(I)c1>>Oc1cc(Br)cc(I)c1 -US06531502B1,3,COc1ccc(C=O)cc1C1CCCC1.Cc1c(Cl)ccc2c1CC(=O)N2>>COc1ccc(C=C2C(=O)Nc3ccc(Cl)c(C)c32)cc1C1CCCC1 -US20130216497A1,6,CCOC(=O)[C@H]1C[C@@H](NS(=O)(=O)C2CC2)C[C@H]1CC>>CC[C@@H]1C[C@H](NS(=O)(=O)C2CC2)C[C@@H]1C(=O)O -US20110306573A1,1,C[C@]1(F)C(O)O[C@H](COC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1.Clc1ncnc2[nH]cc(I)c12>>C[C@@]1(F)[C@H](OC(=O)c2ccccc2)[C@@H](COC(=O)c2ccccc2)O[C@H]1n1cc(I)c2c(Cl)ncnc21 -US20110152318A1,3,CC(C)c1cccc(B(O)O)c1.CC(NC(=O)c1csc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1>>CC(C)c1cccc(-c2nc(C(=O)NC(C)c3cc(F)c(NS(C)(=O)=O)c(F)c3)cs2)c1 -US07691364B2,2,O=C(COc1ccc([N+](=O)[O-])cc1)OCCO.O=C(O)COc1ccc([N+](=O)[O-])cc1>>O=C(COc1ccc([N+](=O)[O-])cc1)OCCOC(=O)COc1ccc([N+](=O)[O-])cc1 -US20110263588A1,2,Cn1nc(C(=O)O)c2c1-c1cc(Cl)ccc1OC2.Nc1cccc(Cl)c1>>Cn1nc(C(=O)Nc2cccc(Cl)c2)c2c1-c1cc(Cl)ccc1OC2 -US20050288346A1,6,CCCc1c(OCCCCOc2ccc(C(=O)OC)cc2)ccc(C(C)=O)c1O>>CCCc1c(OCCCCOc2ccc(C(=O)O)cc2)ccc(C(C)=O)c1O -US20140329804A1,1,COC(=O)c1c(Cl)nc2ccc(C#N)cc2c1Cl.COc1ccc(CN)cc1Cl>>COC(=O)c1c(Cl)nc2ccc(C#N)cc2c1NCc1ccc(OC)c(Cl)c1 -US08653274B2,3,CCOCOc1ccc2oc(B(O)O)cc2c1.CN(C(=O)OC(C)(C)C)c1ccc(Br)c([N+](=O)[O-])n1>>CCOCOc1ccc2oc(-c3ccc(N(C)C(=O)OC(C)(C)C)nc3[N+](=O)[O-])cc2c1 -US20060084640A1,3,Fc1cc(F)cc(C[Zn+])c1.O=C(Cl)c1ccc(C(F)(F)F)cc1>>O=C(Cc1cc(F)cc(F)c1)c1ccc(C(F)(F)F)cc1 -US20110294779A1,2,C1CNC1.CCn1ncc(C(=O)O)c1C(=O)Nc1ccn2cc(-c3ccccc3)nc2c1>>CCn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccn2cc(-c3ccccc3)nc2c1 -US05135737,2,NCCc1ccc([N+](=O)[O-])cc1.O=C(Br)CBr>>O=C(CBr)NCCc1ccc([N+](=O)[O-])cc1 -US20100004271A1,6,CNC(=O)c1c2cc(OC)ccc2nn1C>>CNC(=O)c1c2cc(O)ccc2nn1C -US07005432B2,1,Cc1ncc[nH]1.OCc1cnnc(-c2ccc(F)c(Cl)c2)c1>>Cc1nccn1Cc1cnnc(-c2ccc(F)c(Cl)c2)c1 -US04587050,6,COC(=O)C(C)N1CCCCCC(N=[N+]=[N-])C1=O>>CC(C(=O)O)N1CCCCCC(N=[N+]=[N-])C1=O -US04012524,7,CC(C)C1(C)Cc2cc(O)c(Cl)c(Cl)c2C1=O>>CC(C)C1(C)Cc2cc(O)c(Cl)c(Cl)c2C1O -US20090048112A1,10,Cc1c(OCC(F)(F)F)nn(C)c1C(F)(F)F.O=C1CCC(=O)N1Br>>Cn1nc(OCC(F)(F)F)c(CBr)c1C(F)(F)F -US08642585B2,3,Cc1cc(I)cc(C)c1Br.Cc1ccc(B(O)O)cn1>>Cc1ccc(-c2cc(C)c(Br)c(C)c2)cn1 -US20100137279A1,3,C=CC(=O)N(c1nc(-n2c(C)ccc2C)nc(C)c1Br)N1CCCC1>>Cc1nc(-n2c(C)ccc2C)nc2c1ccc(=O)n2N1CCCC1 -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)NCC2CCC2)cc1.FC(F)(F)c1cnc(Cl)c(Cl)c1>>COC(=O)c1ccc(S(=O)(=O)N(CC2CCC2)c2ncc(C(F)(F)F)cc2Cl)cc1 -US20090143354A1,6,CC(C)(C)[Si](C)(C)OCCN[C@H]1CCN(c2ccc3c(NC(=O)CCC4CCCC4)c(Cl)ccc3n2)C1>>O=C(CCC1CCCC1)Nc1c(Cl)ccc2nc(N3CC[C@H](NCCO)C3)ccc12 -US07196107B2,9,CCOC(=O)COc1ccc(C(O)CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C>>CCOC(=O)COc1ccc(CCCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C -US08299267B2,7,N#Cc1cc(Br)cc(NC(=O)OCc2ccccc2)c1>>NCc1cc(Br)cc(NC(=O)OCc2ccccc2)c1 -US20060160802A1,2,CCCCC1CC(CN(C=O)OCc2ccccc2)(C(=O)O)C1.NNc1nccc(C(F)(F)F)n1>>CCCCC1CC(CN(C=O)OCc2ccccc2)(C(=O)NNc2nccc(C(F)(F)F)n2)C1 -US20060111440A1,3,CC(C)(F)C[C@H](N[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)C(F)(F)F)C(=O)NC1(C#N)CC1.OC(c1ccc(Br)cc1)C(F)(F)F>>CC(C)(F)C[C@H](N[C@@H](c1ccc(-c2ccc(C(O)C(F)(F)F)cc2)cc1)C(F)(F)F)C(=O)NC1(C#N)CC1 -US07423056B2,6,Cc1csc2c1C(C)C1CN(Cc3ccccc3)CC21>>Cc1csc2c1C(C)C1CNCC21 -US05773530,1,CCOC(=O)CCNC(=O)OCc1ccccc1.CI>>CCOC(=O)CCN(C)C(=O)OCc1ccccc1 -US20070123734A1,3,BrC1CCCCC1.[Mg+]c1ccccc1>>c1ccc(C2CCCCC2)cc1 -US20150152108A1,1,CC1CNCCN1Cc1ccccc1.O=C(Nc1cnccn1)N1c2nc(Cl)ccc2N2CC[C@H]1C2>>CC1CN(c2ccc3c(n2)N(C(=O)Nc2cnccn2)[C@H]2CCN3C2)CCN1Cc1ccccc1 -US20120004164A1,6,CCOC(=O)c1sc(N2CCN(CCc3ccccc3)C2=O)nc1C>>Cc1nc(N2CCN(CCc3ccccc3)C2=O)sc1C(=O)O -US20100004222A1,7,O=C1C=COC(COCc2ccccc2)C1>>O=C1CCOC(COCc2ccccc2)C1 -US20140171405A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CN1CCCC1CCN1Cc2cc(Br)ccc2C1=O>>CN1CCCC1CCN1Cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2C1=O -US04019893,8,O=C(OO)c1cccc(Cl)c1.[O-][n+]1ccccc1SCc1ccc(Cl)cc1Cl>>O=S(Cc1ccc(Cl)cc1Cl)c1cccc[n+]1[O-] -US20070259920A1,2,Nc1c2c(nn1-c1cccc(Cl)c1Cl)CCC2.O=C(O)c1cccnc1Oc1cccc(Cl)c1>>O=C(Nc1c2c(nn1-c1cccc(Cl)c1Cl)CCC2)c1cccnc1Oc1cccc(Cl)c1 -US20040204437A1,9,Brc1ccc(Br)nc1.[C-]#N>>N#Cc1ccc(Br)cn1 -US20120245161A1,2,CC(C)(C)OC(=O)NCc1ccc(OCC(N)=O)c(C2CCNCC2)c1.COCCn1cc(C(=O)O)c2cccc(C)c21>>COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)OC(C)(C)C)ccc3OCC(N)=O)CC2)c2cccc(C)c21 -US07087599B2,6,CCCCC12CCC(=O)C(Cc3ccccc3)=C1c1ccc(OC)cc1C2>>CCCCC12CCC(=O)C(Cc3ccccc3)=C1c1ccc(O)cc1C2 -US20120114765A1,2,NCCc1ccc(Br)cc1.O=C(Cl)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(NCCc1ccc(Br)cc1)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US20080306027A1,1,FC(F)Cl.O=Cc1ccc(O)cc1>>O=Cc1ccc(OC(F)F)cc1 -US20110166132A1,6,COC(=O)C(CC1CC1)c1ccc(NC(C)C)cn1>>CC(C)Nc1ccc(C(CC2CC2)C(=O)O)nc1 -US20120214784A1,2,CN.O=C(O)c1cccc(F)c1F>>CNC(=O)c1cccc(F)c1F -US05635510,6,CC(C)(C)OC(=O)N1CCC(C(N)=O)(c2cccnc2)CC1>>NC(=O)C1(c2cccnc2)CCNCC1 -US20150133451A1,1,CNC.Cn1cc(NC(=O)OC(C)(C)C)c(N2CC(C=O)C(C)(C)C2=O)n1>>CN(C)CC1CN(c2nn(C)cc2NC(=O)OC(C)(C)C)C(=O)C1(C)C -US20040235917A1,2,CNc1nc(C)c(S(N)(=O)=O)s1.O=C(O)Cc1ccc(-c2ccccc2F)cc1>>Cc1nc(N(C)C(=O)Cc2ccc(-c3ccccc3F)cc2)sc1S(N)(=O)=O -US04341784,1,CC(=O)NC1CCNC1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)nc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCC(NC(C)=O)C3)nc21 -US05914351,5,O=Cc1cc([N+](=O)[O-])ccc1Cl.OCCO>>O=[N+]([O-])c1ccc(Cl)c(C2OCCO2)c1 -US20130274475A1,2,CN(C)c1cc(N)ccn1.O=C(O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CN(C)c1cc(NC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)ccn1 -US08916557B2,1,CS(=O)(=O)Cc1cccc(Nc2ncnc(-c3ccc(F)cc3F)n2)c1.Cc1cccc(CO)c1>>Cc1cccc(COc2cc(F)ccc2-c2ncnc(Nc3cccc(CS(C)(=O)=O)c3)n2)c1 -US20120149677A1,1,CC(C)(C)C=O.COc1ccc(N)c([N+](=O)[O-])c1>>COc1ccc(NCC(C)(C)C)c([N+](=O)[O-])c1 -US06602872B1,1,CNOC.O=C(Cl)c1cccc(C(F)(F)F)c1>>CON(C)C(=O)c1cccc(C(F)(F)F)c1 -US07115640B2,7,CCNc1ccc(C(C)=O)cc1N=C1SC(=C2Sc3ccccc3N2C)C(=O)N1Cc1ccccc1>>CCNc1ccc(C(C)O)cc1N=C1SC(=C2Sc3ccccc3N2C)C(=O)N1Cc1ccccc1 -US20040192671A1,2,CC(=O)N1CCc2ccc(S(=O)(=O)Cl)cc2CC1.c1ccc2c(c1)CCN2>>CC(=O)N1CCc2ccc(S(=O)(=O)N3CCc4ccccc43)cc2CC1 -US07731985B2,1,CCCCCCCCCCCCN.Cc1cc(Cl)nc(C(C)C)n1>>CCCCCCCCCCCCNc1cc(C)nc(C(C)C)n1 -US20080119466A1,2,CCOC(=O)Cl.Nc1ccc2c(ccn2-c2ccc(NC(=O)N(O)c3ccc(Cl)c(C(F)(F)F)c3)cc2)c1>>CCOC(=O)Nc1ccc2c(ccn2-c2ccc(NC(=O)N(O)c3ccc(Cl)c(C(F)(F)F)c3)cc2)c1 -US20090221642A1,1,CC(C)(C)OC(=O)N1CCC(C)(N2CCC(=O)CC2)C1.Nc1ccccc1N>>CC(C)(C)OC(=O)N1CCC(C)(N2CCC(Nc3ccccc3N)CC2)C1 -US20080200448A1,6,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)N(CC(=O)OC(C)(C)C)S(=O)(=O)Cc3ccccc3)CC2)nc1C>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)N(CC(=O)O)S(=O)(=O)Cc3ccccc3)CC2)nc1C -US06281357B1,2,CNC(c1ccccc1)c1ccccc1.COC(=O)CS(=O)(=O)Cl>>COC(=O)CS(=O)(=O)N(C)C(c1ccccc1)c1ccccc1 -US20120196824A1,3,CB1OB(C)OB(C)O1.Cc1cc2c(I)nn(C3CCCCO3)c2cc1[N+](=O)[O-]>>Cc1cc2c(C)nn(C3CCCCO3)c2cc1[N+](=O)[O-] -US20080318874A1,3,Brc1ccc(C2CC2)cc1.CON(C)C(=O)N(C)OC>>CON(C)C(=O)c1ccc(C2CC2)cc1 -US20120172351A1,1,COC(=O)C[C@@H]1COc2cc(N(Cc3cccc(Br)c3C)C(=O)C(F)(F)F)ccc21.Nc1ccc(F)cn1>>COC(=O)C[C@@H]1COc2cc(N(Cc3cccc(Nc4ccc(F)cn4)c3C)C(=O)C(F)(F)F)ccc21 -US05854245,6,CCOC(=O)COc1ccc(NC(=O)c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2)c(C)c1>>Cc1cc(OCC(=O)O)ccc1NC(=O)c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20080249318A1,2,CCc1ccc(Nc2c(C)cc(Cl)cc2Cl)cc1.O=C(Cl)CCl>>CCc1ccc(N(C(=O)CCl)c2c(C)cc(Cl)cc2Cl)cc1 -US20100105659A1,6,c1ccc(COc2cccn3cnnc23)cc1>>Oc1cccn2cnnc12 -US20150011774A1,1,CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2C(N)=NO)cc1.Cc1oc(=O)oc1CCl>>CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2C(N)=NO)cc1 -US20090215752A1,3,COc1cc(N)cc(OC)c1Br.c1cncc(B2OCCO2)c1>>COc1cc(N)cc(OC)c1-c1cccnc1 -US07304161B2,1,Cc1c(C(=O)NNC(C)(C)C)ccc2c1OC(C(O[SiH](C)C)C(C)(C)C)CO2.Cc1cc(C)cc(C(=O)Cl)c1>>Cc1cc(C)cc(C(=O)N(NC(=O)c2ccc3c(c2C)OC(C(O[SiH](C)C)C(C)(C)C)CO3)C(C)(C)C)c1 -US20070049574A1,3,Cc1c(Br)c(=O)n(-c2ccc(F)cc2)n1C.OB(O)C1CC1>>Cc1c(C2CC2)c(=O)n(-c2ccc(F)cc2)n1C -US20080318925A1,3,COc1ccc(B(O)O)c(OC)c1.Nc1c(C(=O)NC2CC2)nnc2c(Br)cccc12>>COc1ccc(-c2cccc3c(N)c(C(=O)NC4CC4)nnc23)c(OC)c1 -US04851410,1,NCCCCOn1cc(CN2CCCCC2)cn1.O=S1(=O)N=C(Cl)c2ccccc21>>O=S1(=O)N=C(NCCCCOn2cc(CN3CCCCC3)cn2)c2ccccc21 -US20060041123A1,9,[N-]=[N+]=N[C@@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O>>N[C@@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O -US20080056991A1,2,CC(C)N1CCNCC1.O=Cc1cccc(C(=O)O)c1>>CC(C)N1CCN(C(=O)c2cccc(C=O)c2)CC1 -US07803819B2,9,Cc1oc(-c2ccc(OCc3ccccc3)cc2)nc1CCN=[N+]=[N-]>>Cc1oc(-c2ccc(OCc3ccccc3)cc2)nc1CCN -US07179835B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)NCCN>>CC(C)NCCNC(=O)OC(C)(C)C -US20140309219A1,1,BrCCC1OCCO1.Clc1ncc2c(n1)N1CCOC[C@H]1CN2>>Clc1ncc2c(n1)N1CCOC[C@H]1CN2CCC1OCCO1 -US20110059992A1,3,NC1=NC(c2cccc(Br)c2)(c2ccnc(Cl)c2)c2ccccc21.OB(O)c1cncnc1>>NC1=NC(c2cccc(-c3cncnc3)c2)(c2ccnc(Cl)c2)c2ccccc21 -US08927588B2,2,CC(C)CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1N.CCc1[nH]c(C(=O)O)nc1Cl>>CCc1[nH]c(C(=O)N[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2OCC(C)C)nc1Cl -US20150166569A1,3,CC[Si](C#CC(C)(O)CF)(CC)CC.NC(=O)c1nc2n(c1CN1CCOCC1)CCOc1ccc(Br)cc1-2>>CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(CN3CCOCC3)n1CCO2)CF -US04954501,1,CC1CC(=O)NN=C1c1ccc(Cl)c([N+](=O)[O-])c1.NCCCc1c[nH]cn1>>CC1CC(=O)NN=C1c1ccc(NCCCc2c[nH]cn2)c([N+](=O)[O-])c1 -US20050154015A1,2,CC(=O)OC(C)=O.CN(C)c1ccc2c(c1)OC(c1cc3c(c(C#N)c1N)OCO3)=CC2>>CC(=O)Nc1c(C2=CCc3ccc(N(C)C)cc3O2)cc2c(c1C#N)OCO2 -US05283251,3,COC(=O)CCC(=O)Cl.Cc1cc2ccccc2[nH]1>>COC(=O)CCC(=O)c1c(C)[nH]c2ccccc12 -US20140343033A1,1,C1COCCN1.C[C@H](N)c1nc2ccn(C)c2cc1Br>>C[C@H](N)c1nc2ccn(C)c2cc1N1CCOCC1 -US04778897,2,CO.COc1ccccc1Sc1ccccc1C(=O)O>>COC(=O)c1ccccc1Sc1ccccc1OC -US08802853B2,7,O=[N+]([O-])c1cnc2ccccc2c1NCCCCO>>Nc1cnc2ccccc2c1NCCCCO -US08609647B2,6,CC(C)(C)OC(=O)N1CCCC2(CCN2C(=O)OCc2ccccc2)C1>>O=C(OCc1ccccc1)N1CCC12CCCNC2 -US20140315888A1,9,CN1CCN(c2nc3ncc(Br)cc3nc2Cl)CC1.NN>>CN1CCN(c2nc3ncc(Br)cc3nc2NN)CC1 -US07081279B2,6,CCOc1ccc(C2CCC3(CC2)OCCO3)c(F)c1F>>CCOc1ccc(C2CCC(=O)CC2)c(F)c1F -US20020151595A1,6,COC(=O)C(C)c1cc(C#N)ccc1OCc1ccccc1>>CC(C(=O)O)c1cc(C#N)ccc1OCc1ccccc1 -US20090137548A1,3,COC(=O)c1ccc(-c2ccc(OC)c(Br)c2)c(C)c1.OCc1cc(C(F)(F)F)ccc1Cl>>COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3CO)c2)c(C)c1 -US07094789B2,7,O=[N+]([O-])c1cccc2c(Cl)nccc12>>Nc1cccc2c(Cl)nccc12 -US20100210619A1,7,CCOC(=O)CCS(=O)(=O)Cc1ccc([N+](=O)[O-])cc1>>CCOC(=O)CCS(=O)(=O)Cc1ccc(N)cc1 -US20080171754A1,6,CCOC(=O)[C@@H]1C[C@H]1c1ccncc1>>O=C(O)[C@@H]1C[C@H]1c1ccncc1 -US08372842B2,6,CC(C)(C)OC(=O)N1CCC[C@H]1[C@@H](C(=O)N1CCN(c2c(Cl)cnc3[nH]ncc23)CC1)c1ccc(Cl)cc1>>O=C([C@@H](c1ccc(Cl)cc1)[C@@H]1CCCN1)N1CCN(c2c(Cl)cnc3[nH]ncc23)CC1 -US20090325993A1,2,Nc1ccc(F)c(F)c1.O=C(O)CN1C(=O)C(c2ccc(Cl)cc2)=NC12CCOCC2>>O=C(CN1C(=O)C(c2ccc(Cl)cc2)=NC12CCOCC2)Nc1ccc(F)c(F)c1 -US20080300241A9,9,Nc1cc(Cl)cc2c1C(O)(C(F)(F)F)CC(=O)N2>>Nc1cccc2c1C(O)(C(F)(F)F)CC(=O)N2 -US05663162,2,CC(=O)OC(C)=O.NCc1ncc2sccn12>>CC(=O)NCc1ncc2sccn12 -US20080146568A1,1,CCOC(=O)C(C)=O.Cc1cc(Cl)ccc1NN>>CCOC(=O)C(C)=NNc1ccc(Cl)cc1C -US20040044212A1,7,COc1cc(C2=NCCc3ccc(Cl)cc32)ccc1[N+](=O)[O-]>>COc1cc(C2=NCCc3ccc(Cl)cc32)ccc1N -US20010000513A1,9,NO.O=C(O)CCC(=O)c1ccc(-c2ccc(F)cc2)cc1>>O=C(O)CCC(=NO)c1ccc(-c2ccc(F)cc2)cc1 -US20140011777A1,9,CCCc1nc2c(Cl)nc3ccccc3c2n1CC1(O)CCC1.N>>CCCc1nc2c(N)nc3ccccc3c2n1CC1(O)CCC1 -US06951879B2,1,CN.Cc1sc2cc(OCCOS(C)(=O)=O)ccc2c1-c1ccc(C(F)(F)F)cc1>>CNCCOc1ccc2c(-c3ccc(C(F)(F)F)cc3)c(C)sc2c1 -US05521179,6,CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F>>CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(N)c1=O)C(=O)C(F)(F)F -US20140228394A1,1,Cc1ccc(S(=O)(=O)n2ccc3ccc(Br)cc32)cc1.Cc1ccncc1N1CCNC1=O>>Cc1ccc(S(=O)(=O)n2ccc3ccc(N4CCN(c5cnccc5C)C4=O)cc32)cc1 -US20100137313A1,4,COCCCNc1nc(Nc2ccc(F)c(Cl)c2)ncc1C(N)=S.O=C(CBr)c1ccncc1>>COCCCNc1nc(Nc2ccc(F)c(Cl)c2)ncc1-c1nc(-c2ccncc2)cs1 -US05266585,1,Clc1ccc(CBr)cc1.OCC1COC(Cn2cncn2)(c2ccc(Oc3ccccc3)cc2)O1>>Clc1ccc(COCC2COC(Cn3cncn3)(c3ccc(Oc4ccccc4)cc3)O2)cc1 -US20110086882A1,7,CCOC(=O)c1cc(Cl)c(I)c(OC)c1>>COc1cc(CO)cc(Cl)c1I -US05451596,1,BrCc1ccc(-c2nc3ccccc3o2)cc1.OCC1(NC(c2ccccc2)(c2ccccc2)c2ccccc2)CCCC1>>c1ccc(C(NC2(COCc3ccc(-c4nc5ccccc5o4)cc3)CCCC2)(c2ccccc2)c2ccccc2)cc1 -US20110144105A1,7,C(=C(c1ccc2c(c1)OCCO2)c1cc2cccnc2[nH]1)C1CCCC1>>c1cnc2[nH]c(C(CC3CCCC3)c3ccc4c(c3)OCCO4)cc2c1 -US20130065925A1,6,CC(C)(C)OC(=O)NC1CCN(CC2CCC(F)(F)CC2)CC1>>NC1CCN(CC2CCC(F)(F)CC2)CC1 -US04839367,1,CCI.CCOC(=O)CN(C(=O)C(C)CS)C1CCCC1>>CCOC(=O)CN(C(=O)C(C)CSCC)C1CCCC1 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.Cc1cc(C=O)cc2c3ccccc3n(C)c12>>Cc1cc(CN2CCC(c3cccc(NC(=O)C(C)C)c3)CC2)cc2c3ccccc3n(C)c12 -US20100035326A1,5,NCc1ccc(C(=O)O)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)c1ccc(CNC(=O)C(F)(F)F)cc1 -US20130217702A1,6,Cc1nc(-c2c(Cl)c3ccccc3n2-c2ccc(CNC(=O)C3(NC(=O)OC(C)(C)C)CC3)cc2)no1>>Cc1nc(-c2c(Cl)c3ccccc3n2-c2ccc(CNC(=O)C3(N)CC3)cc2)no1 -US20090042841A1,3,C#CC=C1CCN(c2ncccc2[N+](=O)[O-])CC1.Cc1cccc(Br)n1>>Cc1cccc(C#CC=C2CCN(c3ncccc3[N+](=O)[O-])CC2)n1 -US20120149721A1,2,COCC(=O)Cl.Cc1[nH]c2c(-c3cc(F)ccc3OCC3CC3)ncnc2c1C(=O)N[C@@H]1CCNC[C@H]1O>>COCC(=O)N1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4cc(F)ccc4OCC4CC4)ncnc23)[C@H](O)C1 -US20060084645A1,1,OC1CCN(c2cc(-c3ccccc3)nc(Cl)n2)CC1.c1cc[nH]c1>>OC1CCN(c2cc(-c3ccccc3)nc(-n3cccc3)n2)CC1 -US08486967B2,1,CC(C)(O)c1cc(-c2ccc(Cl)cc2)nc(Cl)n1.Cc1nsc(N2CCC(N)CC2)n1>>Cc1nsc(N2CCC(Nc3nc(-c4ccc(Cl)cc4)cc(C(C)(C)O)n3)CC2)n1 -US08129376B2,1,CC(C)(C)OC(=O)N1CCC(Nc2ccccc2Cl)CC1.CI>>CN(c1ccccc1Cl)C1CCN(C(=O)OC(C)(C)C)CC1 -US05294612,1,N#Cc1ccncc1Cl.OC1CCC1>>N#Cc1ccncc1OC1CCC1 -US20090270418A1,6,Cc1ccc(NC(=O)OC(C)(C)C)cc1NC(=O)CN1C(=O)c2ccccc2C1=O>>Cc1ccc(N)cc1NC(=O)CN1C(=O)c2ccccc2C1=O -US08293772B2,7,Cc1ccc([N+](=O)[O-])cc1C(=O)c1ccc(Nc2cccc(F)c2)cc1Cl>>Cc1ccc(N)cc1C(=O)c1ccc(Nc2cccc(F)c2)cc1Cl -US07449466B2,2,COc1cc(F)c(N2CCNCC2)cc1F.O=S(=O)(Cl)CCc1ccccc1>>COc1cc(F)c(N2CCN(S(=O)(=O)CCc3ccccc3)CC2)cc1F -US20070155727A1,1,CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)CC1(CN)CCCC1.COC(=O)c1ccc(C=O)cc1>>COC(=O)c1ccc(CNCC2(CN(C)CC(=O)Nc3ccc(Oc4ccccc4)cc3)CCCC2)cc1 -US05112998,6,CC(=O)O[C@@H]1CC2=CC=C3[C@@H]4CC[C@H](C(C)C5OCCO5)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@@H](OC(=O)c2ccccc2)C1>>CC(=O)O[C@@H]1CC2=CC=C3[C@@H]4CC[C@H](C(C)C=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@@H](OC(=O)c2ccccc2)C1 -US06258948B1,6,COC(=O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CNc2ccccc21>>COC(=O)CN1C(=O)[C@@H](N)CNc2ccccc21 -US20090274650A1,2,CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(O)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2.CN=C=O>>CNC(=O)Oc1ccc(C[C@H](NC(=O)O[C@H]2CO[C@H]3OCC[C@@H]23)[C@H](O)CN(CC(C)C)S(=O)(=O)c2ccc3c(c2)OCO3)cc1 -US20020165234A1,6,CCOC(=O)c1ccc(Oc2ccc(N(CC(C)C)C[C@H](O)COc3cccc4[nH]c5ccccc5c34)cc2)c(I)c1>>CC(C)CN(C[C@H](O)COc1cccc2[nH]c3ccccc3c12)c1ccc(Oc2ccc(C(=O)O)cc2I)cc1 -US20090264399A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2c(C(N)=O)cnc3[nH]ccc23)C1>>NC(=O)c1cnc2[nH]ccc2c1N[C@@H]1CCCNC1 -US20080058311A1,6,CC(C)CN(CC(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1)C(=O)OC(C)(C)C>>CC(C)CNCC(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1 -US20130281415A9,7,COC(=O)c1cc(C#N)c(N)cc1OC>>COc1cc(N)c(C#N)cc1CO -US20100331372A1,2,CCc1cc(-c2noc(-c3cc(CC(C)C)cc(C)n3)n2)cc(C)c1OC[C@@H](O)CN.O=C(O)CO>>CCc1cc(-c2noc(-c3cc(CC(C)C)cc(C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO -US20060058305A1,6,CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(OC(=O)[C@H](C)NC(=O)OC(C)(C)C)C1>>CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(OC(=O)[C@H](C)N)C1 -US20150191492A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1Cc2c(Cl)cc(Cl)cc2CN1>>CC(C)(C)OC(=O)N1Cc2cc(Cl)cc(Cl)c2CC1C(=O)O -US20020037891A1,1,CCn1cc(C(=O)O)c(=O)c2cc3cc(F)c(Cl)cc3nc21.Fc1ccc(N2CCNCC2)cc1>>CCn1cc(C(=O)O)c(=O)c2cc3cc(F)c(N4CCN(c5ccc(F)cc5)CC4)cc3nc21 -US07803806B2,3,CC(O)c1cccc(Nc2nccc(-c3ccc(Br)s3)n2)c1.Cc1cccc(C)c1B(O)O>>Cc1cccc(C)c1-c1ccc(-c2ccnc(Nc3cccc(C(C)O)c3)n2)s1 -US05491148,2,N[C@@H]1CN2CCC1CC2.O=C(O)c1ccccc1Cc1ccccc1>>O=C(N[C@@H]1CN2CCC1CC2)c1ccccc1Cc1ccccc1 -US20110046134A1,3,CCOC(=O)c1ccc(Br)[nH]1.OB(O)c1ccccc1>>CCOC(=O)c1ccc(-c2ccccc2)[nH]1 -US20070249670A1,2,COC(=O)[C@@H](N)C1CCCCC1.O=C(Nc1sc(-c2ccccc2)cc1C(=O)O)Nc1c(Cl)cccc1Cl>>COC(=O)[C@@H](NC(=O)c1cc(-c2ccccc2)sc1NC(=O)Nc1c(Cl)cccc1Cl)C1CCCCC1 -US20120022254A1,7,O=[N+]([O-])c1ccc(-c2nc3cnccc3o2)cc1>>Nc1ccc(-c2nc3cnccc3o2)cc1 -US20060211695A1,1,CN1CCN(CCO)CC1.Cc1c(O)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12>>Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12 -US08940889B2,6,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCc3ccccc3)ccc21>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(O)ccc21 -US20100137610A1,1,CCOC(=O)CCCN.CN(c1cccc2cc(-c3ncc(CCl)s3)[nH]c12)S(=O)(=O)c1cccs1>>CCOC(=O)CCCNCc1cnc(-c2cc3cccc(N(C)S(=O)(=O)c4cccs4)c3[nH]2)s1 -US20030171377A1,1,COC(=O)c1ccc(O)nc1.Cc1oc(-c2ccccc2)nc1CCO>>COC(=O)c1ccc(OCCc2nc(-c3ccccc3)oc2C)nc1 -US05446039,6,COc1cc(=O)c2ccc(Cl)cc2[nH]c1=O>>O=c1[nH]c2cc(Cl)ccc2c(=O)cc1O -US20150126517A1,9,CC1NCC(c2ccc(Cl)cc2)c2ccc(-c3ccc(Cl)nn3)cc21>>CC1NCC(c2ccc(Cl)cc2)c2ccc(-c3cccnn3)cc21 -US06982348B2,2,NC(Cc1ccc(C(F)(F)F)o1)C(O)c1ccc(F)cc1.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)NC(Cc1ccc(C(F)(F)F)o1)C(O)c1ccc(F)cc1 -US20080194552A1,7,COc1ccc(C#Cc2cnc(N)nc2)cc1[N+](=O)[O-]>>COc1ccc(C#Cc2cnc(N)nc2)cc1N -US06265575B1,1,COC(=O)c1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(O)cc3)sc2c1.ClCCN1CCCC1>>COC(=O)c1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(OCCN4CCCC4)cc3)sc2c1 -US20110178053A1,3,Brc1cnc2[nH]c3cnc(-c4cccnc4)cc3c2c1.CC(C)(C)OC(=O)N1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cnc4[nH]c5cnc(-c6cccnc6)cc5c4c3)cc2)CC1 -US06541499B1,6,COc1cc(Cn2c(-c3ccc(OCCN4CCCC4)cc3)nc3cc(O[Si](C)(C)C(C)(C)C)ccc32)ccc1CNCc1ccccc1>>COc1cc(Cn2c(-c3ccc(OCCN4CCCC4)cc3)nc3cc(O)ccc32)ccc1CNCc1ccccc1 -US06384051B1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Nc1ccc(Sc2ccccc2)c(Cl)c1>>COc1cc2ncc(C#N)c(Nc3ccc(Sc4ccccc4)c(Cl)c3)c2cc1OC -US07897628B2,1,COC(=O)c1ncccc1S.Cc1ccc(NC(=O)Nc2ncc(Br)s2)c(C(=O)C2CCCC2)c1>>COC(=O)c1ncccc1Sc1cnc(NC(=O)Nc2ccc(C)cc2C(=O)C2CCCC2)s1 -US20150045339A1,1,CCCNc1nc(Cl)ncc1C#CCCCNC(=O)[C@H](C)N(C)C(=O)/C=C/CN(C)C.Nc1cccc(Cl)c1>>CCCNc1nc(Nc2cccc(Cl)c2)ncc1C#CCCCNC(=O)[C@H](C)N(C)C(=O)/C=C/CN(C)C -US20050038035A1,6,Cc1ccc(C2=C(C(=O)Nc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3)CCCC2)cc1>>Cc1ccc(C2=C(C(=O)Nc3ccc(N4CCNCC4)cc3)CCCC2)cc1 -US05714191,8,N#Cc1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1N.OO>>N#Cc1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1[N+](=O)[O-] -US07612075B2,6,O=C1CN(C(=O)OCc2ccccc2)CCN1Cc1cc2c(Cl)nccc2n1S(=O)(=O)c1ccccc1>>O=C1CNCCN1Cc1cc2c(Cl)nccc2n1S(=O)(=O)c1ccccc1 -US08592360B2,7,C=C(C#N)C1CC(C)(C)CC1C>>CC(C#N)C1CC(C)(C)CC1C -US07427632B2,1,CC(C)=O.Cc1c[nH]c2cc(C(=O)N[C@@H](COCC3CCNCC3)c3ccccc3)ccc12>>Cc1c[nH]c2cc(C(=O)N[C@@H](COCC3CCN(C(C)C)CC3)c3ccccc3)ccc12 -US08124809B2,3,Brc1ccccc1.C#Cc1ccccc1>>C(#Cc1ccccc1)c1ccccc1 -US20080293716A1,2,CC1(C)OB(c2ccc(C(=O)O)s2)OC1(C)C.COc1cccc(CN)c1>>COc1cccc(CNC(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)s2)c1 -US20120077787A1,2,CC(C)(C)OC(=O)NCc1cc2ncc(N)n2cc1-c1ccc(Cl)cc1Cl.O=C(O)C1CCOCC1>>CC(C)(C)OC(=O)NCc1cc2ncc(NC(=O)C3CCOCC3)n2cc1-c1ccc(Cl)cc1Cl -US20030139464A1,6,CCOC(=O)C(CN1C(=O)c2ccc(F)cc2C1=O)C1(C)OCCO1>>CCOC(=O)C(CN1C(=O)c2ccc(F)cc2C1=O)C(C)=O -US05998433,3,C1CCNC1.C=O.O=C(c1ccc(CCc2ccccc2)cc1)N1CCc2ccoc2C1>>O=C(c1ccc(CCc2ccccc2)cc1)N1CCc2cc(CN3CCCC3)oc2C1 -US20040235822A1,2,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3CC(C)C)cc1.CCCn1cncc1CSc1nc2cc(N)ccc2n1C>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc4c(c2)nc(SCc2cncn2CCC)n4C)CCN3CC(C)C)cc1 -US05591762,6,CCCc1nc2c(C)cc(-c3csc(C)n3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCc1nc2c(C)cc(-c3csc(C)n3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20140213448A1,1,CN(C(=O)CCNS(C)(=O)=O)c1cn(-c2cccnc2)nc1Cl.N#CCBr>>CN(C(=O)CCN(CC#N)S(C)(=O)=O)c1cn(-c2cccnc2)nc1Cl -US07531553B2,6,CC(=O)Nc1ccc(C(F)(F)F)c(OC[C@H]2CCCN2C)c1>>CN1CCC[C@@H]1COc1cc(N)ccc1C(F)(F)F -US20080166358A1,4,COCCOc1cc(N)c(C(=O)OC)cc1OCCOC.NC=O>>COCCOc1cc2nc[nH]c(=O)c2cc1OCCOC -US20150218124A1,6,COc1cc(C#N)c(C)c(C#N)c1O>>Cc1c(C#N)cc(O)c(O)c1C#N -US20110269738A1,1,CCc1c(C=O)cccc1-c1nnc(-c2ccc(CC(C)C)c(C#N)c2)s1.COC(=O)C1CNC1>>CCc1c(CN2CC(C(=O)OC)C2)cccc1-c1nnc(-c2ccc(CC(C)C)c(C#N)c2)s1 -US20130072506A1,1,BrCc1ccccc1.Nc1ncnc2c1nc(Br)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>OC[C@H]1O[C@@H](n2c(Br)nc3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O -US08722683B2,2,N[C@@H]1CC[C@@H](CCN2CCN(c3cccc4c3OCO4)CC2)CC1.O=C(O)Cc1ccc2c(c1)OCO2>>O=C(Cc1ccc2c(c1)OCO2)N[C@@H]1CC[C@@H](CCN2CCN(c3cccc4c3OCO4)CC2)CC1 -US05824679,1,COc1ccccc1S(=O)(=O)N(c1cc(C)cc(OCCN)c1)C(C)(C)P(=O)=O.Clc1cnnc(Cl)c1Cl>>COc1ccccc1S(=O)(=O)N(c1cc(C)cc(OCCNc2cnnc(Cl)c2Cl)c1)C(C)(C)P(=O)=O -US20100075942A1,6,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2ncccc2Cl)cc1>>Nc1ccccc1NC(=O)c1ccc(-c2ncccc2Cl)cc1 -US20140296256A1,3,COC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(Br)c1.OB(O)c1cncc2ccccc12>>COC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(-c2cncc3ccccc23)c1 -US20070066634A2,1,C1=C(c2c[nH]c3ccccc23)CCNC1.CSc1nc(C)c(CCCl)c(=O)n1C>>CSc1nc(C)c(CCN2CC=C(c3c[nH]c4ccccc34)CC2)c(=O)n1C -US04575503,1,CC(C)(C)OC(=O)CBr.O=C1Nc2ccccc2CCC1NC(CCc1ccccc1)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)CN1C(=O)C(NC(CCc2ccccc2)C(=O)OCc2ccccc2)CCc2ccccc21 -US20120029037A1,1,CC(=O)NN(C(=O)OC(C)(C)C)c1cccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c1.CI>>CC(=O)N(C)N(C(=O)OC(C)(C)C)c1cccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c1 -US20100286152A1,1,CN1CCNCC1.O=C(O)C(Br)c1cccc2c1OCCO2>>CN1CCN(C(C(=O)O)c2cccc3c2OCCO3)CC1 -US20080255124A1,6,CC(=O)Nc1ccc(OCc2ccccc2)nc1>>CC(=O)Nc1ccc(O)nc1 -US20130150622A1,1,BrCc1ccccc1.O=C(O)/C=C/c1cccc(O)c1>>O=C(O)/C=C/c1cccc(OCc2ccccc2)c1 -US05342947,6,CC(=O)Nc1cc2c(cc1C(=O)CCl)OCO2>>Nc1cc2c(cc1C(=O)CCl)OCO2 -US20100029605A1,1,CSc1cc(-n2nc(C)cc2N)ncn1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Br>>CSc1cc(-n2nc(C)cc2Nc2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2C)ncn1 -US04471138,1,CC(C)(C)N.CC(O)OCCCl>>CC(O)OCCNC(C)(C)C -US20140051702A1,6,c1ccc(CN2CCCCC2CN(c2ccccc2)C2Cc3ccccc3C2)cc1>>c1ccc(N(CC2CCCCN2)C2Cc3ccccc3C2)cc1 -US20130065925A1,1,CCCCCCN1CCC(NC(=O)[C@@]2(CC(=O)OC(C)(C)C)CNC[C@H]2C)CC1.FC(F)c1cccc(Cl)c1CBr>>CCCCCCN1CCC(NC(=O)[C@@]2(CC(=O)OC(C)(C)C)CN(Cc3c(Cl)cccc3C(F)F)C[C@H]2C)CC1 -US20150080426A1,3,C=O.CC(=O)CCC(C)C.CNC>>CC(=O)C(CC(C)C)CN(C)C -US05708007,6,COc1cccc2cc(-c3ccncc3)oc12>>Oc1cccc2cc(-c3ccncc3)oc12 -US07396939B2,1,C=O.COCCNc1c(S(C)(=O)=O)ccc(C(=O)O)c1C>>COCCN(C)c1c(S(C)(=O)=O)ccc(C(=O)O)c1C -US20130267493A1,1,OC(CCCCl)c1ccc(Br)cc1>>Brc1ccc(C2CCCO2)cc1 -US20140100231A1,1,COc1ccc(CO)cc1.COc1ccc(Cn2nc(CO)cc(Br)c2=O)cc1>>COc1ccc(COc2cc(CO)nn(Cc3ccc(OC)cc3)c2=O)cc1 -US20140243544A1,1,CC(C)C(=O)O.CC(Cl)OC(=O)Oc1ccc2c(c1)OCO2>>CC(OC(=O)Oc1ccc2c(c1)OCO2)OC(=O)C(C)C -US20120238541A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(Br)cccc4c3=O)cc2)CCC1.Cc1n[nH]cc1B1OC(C)(C)C(C)(C)O1>>Cc1n[nH]cc1-c1cccc2c(=O)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)oc12 -US20100168105A1,2,COc1ccc(N2CCNCC2)cc1.O=C(O)C1CC12CCN(C1CCOCC1)CC2>>COc1ccc(N2CCN(C(=O)C3CC34CCN(C3CCOCC3)CC4)CC2)cc1 -US07956216B2,6,COC(=O)c1cccc(CCC(C)C)c1>>CC(C)CCc1cccc(C(=O)O)c1 -US20090176792A1,1,CN1CCNCC1.ClC(c1ccccc1)c1ccccc1>>CN1CCN(C(c2ccccc2)c2ccccc2)CC1 -US05691322,7,CCOC(=O)c1c(-c2ccc(F)cc2)cc(-c2ccccc2)nc1C>>Cc1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1CO -US08084620B2,2,CS(=O)(=O)Cl.NC(=O)c1ccc(-c2ccccc2F)c2c1[nH]c1cc(CO)ccc12>>CS(=O)(=O)OCc1ccc2c(c1)[nH]c1c(C(N)=O)ccc(-c3ccccc3F)c12 -US20090036420A1,2,COc1cccc(N)c1.O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>COc1cccc(NC(=O)c2ccc(F)c([N+](=O)[O-])c2)c1 -US20090227799A1,7,CC(C)=Cc1cccc(CN)c1>>CC(C)Cc1cccc(CN)c1 -US08569535B2,1,CC(C)O.CCOC(=O)C1(NCc2cccc(C)c2O)Cc2ccccc2C1>>CCOC(=O)C1(NCc2cccc(C)c2OC(C)C)Cc2ccccc2C1 -US20080221097A1,2,C1COCCN1.Cn1cnc2c(Nc3cccc(Cl)c3)ncc(C(=O)O)c21>>Cn1cnc2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c21 -US04752645,9,C=CCC1(C(=O)OC)C(=O)Nc2ccc(C(F)(F)F)cc2CC1c1ccccc1OC>>C=CCC1C(=O)Nc2ccc(C(F)(F)F)cc2CC1c1ccccc1OC -US20060264460A1,1,CC(C)(C)OC(=O)COc1ccc(C=O)cc1Br.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)COc1ccc(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)cc1Br -US20150152048A1,6,COC(=O)c1ccc2c(c(Cl)cn2C)c1F>>Cn1cc(Cl)c2c(F)c(C(=O)O)ccc21 -US07238714B2,1,CSc1cccc(O)c1.C[C@H](NC(=O)c1cc(Cl)cnc1Cl)c1ccc(C(=O)OC(C)(C)C)cc1>>CSc1cccc(Oc2ncc(Cl)cc2C(=O)N[C@@H](C)c2ccc(C(=O)OC(C)(C)C)cc2)c1 -US04480112,2,CC(=O)CC(=O)N[C@@H](CC(=O)O)C(=O)O>>CC(=O)CC(=O)N[C@H]1CC(=O)OC1=O -US08034812B2,2,CC1(C)C(C(=O)O)C1(C)C.Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(N)cn4n3)ccc2F)n(C)n1>>Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5C(C)(C)C5(C)C)cn4n3)ccc2F)n(C)n1 -US20150274665A1,1,CCc1[nH]cc(C(Cl)C(F)(F)F)c(=O)c1O.CNC>>CCc1[nH]cc(C(N(C)C)C(F)(F)F)c(=O)c1O -US06211387B1,3,CCOC(=O)/C=C(\I)C(=O)OCC.Clc1ccc(I)c(Cl)c1>>CCOC(=O)/C=C(/C(=O)OCC)c1ccc(Cl)cc1Cl -US08026257B2,9,CC(C)(C)OC(=O)N1CCC(COC(COS(C)(=O)=O)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1.[C-]#N>>CC(C)(C)OC(=O)N1CCC(COC(CC#N)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1 -US06689806B1,3,O=C1Cc2c(CCO)cccc2N1.O=Cc1ccc2[nH]ccc2c1>>O=C1Nc2cccc(CCO)c2C1=Cc1ccc2[nH]ccc2c1 -US20060004043A1,6,N#Cc1ccc2c(c1)c(-c1ccc3cc(OCCN4CCCC4)ccc3c1)nn2C1CCCCO1>>N#Cc1ccc2[nH]nc(-c3ccc4cc(OCCN5CCCC5)ccc4c3)c2c1 -US08003658B2,1,CN1CCNCC1.Cc1ccc(Oc2ccc(Nc3ncnc4ccc(NC(=O)CCNC(=O)CCl)cc34)cc2C)cn1>>Cc1ccc(Oc2ccc(Nc3ncnc4ccc(NC(=O)CCNC(=O)CN5CCN(C)CC5)cc34)cc2C)cn1 -US20070173646A1,1,BrCCOc1ccccc1.N#CC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>N#CC(c1ccccc1)(c1ccccc1)C12CC[N+](CCOc3ccccc3)(CC1)CC2 -US05200109,1,CCCCC(=O)O.CCCCCCCCCCc1nnc(-c2ccc(O)c(F)c2)s1>>CCCCCCCCCCc1nnc(-c2ccc(OC(=O)CCCC)c(F)c2)s1 -US20060019958A1,2,Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)c1scc(Br)c1O>>O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1scc(Br)c1O -US08309734B2,2,Cc1ccc2c(c1)CCCN2.O=C(O)c1cccnc1Oc1cccc(C(F)(F)F)c1>>Cc1ccc2c(c1)CCCN2C(=O)c1cccnc1Oc1cccc(C(F)(F)F)c1 -US06416861B1,7,O=Cc1ccc(Br)nc1>>OCc1ccc(Br)nc1 -US20100168101A1,1,NNC(=O)COc1ccc(I)cc1.O=C1Nc2ccc(I)cc2C1=O>>O=C(COc1ccc(I)cc1)NN=C1C(=O)Nc2ccc(I)cc21 -US20120101079A1,7,COCC#Cc1nc(N2CCOCC2)cc(C)c1C(=O)OC>>COCCCc1nc(N2CCOCC2)cc(C)c1C(=O)OC -US20070155727A1,2,Nc1ccc(Oc2ccccc2)cc1.O=C(Br)CBr>>O=C(CBr)Nc1ccc(Oc2ccccc2)cc1 -US20030171364A1,6,CCn1nc(C)c2c1C(=O)NCC(c1cccc(OC)c1)=N2>>CCn1nc(C)c2c1C(=O)NCC(c1cccc(O)c1)=N2 -US20110039852A1,2,CC(=O)Cl.COC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CNCCN(C)C)c1>>COC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CCN(C)C)C(C)=O)c1 -US05859012,7,N#Cc1ccc(C=O)cc1>>N#Cc1ccc(CO)cc1 -US20140018506A1,7,CCOC(=O)C(=CC(C)(C)C)C(=O)OCC>>CCOC(=O)C(CC(C)(C)C)C(=O)OCC -US20020013478A1,3,CCC(=O)Cl.CCCc1cc(=O)oc2cc(O)cc(O)c12>>CCCc1cc(=O)oc2c(C(=O)CC)c(O)cc(O)c12 -US20070129416A1,2,C1CC2CNCCN2C1.CC(C)Oc1cc(C(C)(C)C)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl>>CC(C)Oc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN2CCCC2C1 -US07704994B2,1,N#Cc1ccc(F)c(F)c1.Oc1ccc2c(c1)CCN(C1CCC1)CC2>>N#Cc1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)c(F)c1 -US20140303149A1,2,COc1cc(C(=O)O)c(Cl)cc1[N+](=O)[O-].Nc1ccccc1>>COc1cc(C(=O)Nc2ccccc2)c(Cl)cc1[N+](=O)[O-] -US20120028961A1,3,CC(C)(C)OC(=O)NCc1ccc(Br)nc1.[Zn+]CC1CCCCC1>>CC(C)(C)OC(=O)NCc1ccc(CC2CCCCC2)nc1 -US06858638B2,2,Nc1ccc2[nH]ncc2c1.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1>>O=S(=O)(Nc1ccc2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1 -US20070265262A1,2,NC1CC1.O=C(O)c1ccc(Br)cc1>>O=C(NC1CC1)c1ccc(Br)cc1 -US20150141413A1,2,COc1ccc(CN[C@@](C)(CSC(C)(C)C(=O)O)c2cc(Br)ccc2F)c(OC)c1>>COc1ccc(CN2C(=O)C(C)(C)SC[C@@]2(C)c2cc(Br)ccc2F)c(OC)c1 -US20070049603A1,7,CCOC(=O)c1sc2cnccc2c1N>>Nc1c(CO)sc2cnccc12 -US20080293782A1,6,CS(=O)(=O)Oc1cccc(-c2ccc(OCc3ccccc3)c(N3CC(=O)NS3(=O)=O)c2)c1>>CS(=O)(=O)Oc1cccc(-c2ccc(O)c(N3CC(=O)NS3(=O)=O)c2)c1 -US20090186870A1,1,CC(C)I.CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(OC[C@H]4CCCNC4)ccc3Cl)sc2c1>>CC(C)N1CCC[C@H](COc2ccc(Cl)c(C(=O)NC(=O)Nc3nc4ccc(S(C)(=O)=O)cc4s3)c2)C1 -US20060217418A1,2,CC(C)(C(=O)O)c1ccc(Cl)cc1.CC(C)C(=O)Nc1cccc(C2CCN(CCCN)CC2)c1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCNC(=O)C(C)(C)c3ccc(Cl)cc3)CC2)c1 -US20130040941A1,2,CN(CCN)C(=O)OC(C)(C)C.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>CN(CCNS(=O)(=O)c1ccccc1[N+](=O)[O-])C(=O)OC(C)(C)C -US20080221100A1,2,O=C(Nc1cccc(F)c1)NC1CCNCC1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(Nc1cccc(F)c1)NC1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 -US07858781B2,6,CC(C)(C)OC(=O)NC1CCN(CCN2CCC[C@@H](O)C2)CC1>>NC1CCN(CCN2CCC[C@@H](O)C2)CC1 -US06458817B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)NCCc1ccc([N+](=O)[O-])cc1 -US06924300B2,1,CCOC(=O)CCCC/C(=N\OCc1ccc(O)cc1)c1ccccc1.ClCc1nc(-c2ccccc2)no1>>CCOC(=O)CCCC/C(=N\OCc1ccc(OCc2nc(-c3ccccc3)no2)cc1)c1ccccc1 -US20030119807A1,6,COC(=O)c1nc([C@H](CCCC2CCCCC2)CC(=O)NOCc2ccccc2)oc1C>>Cc1oc([C@H](CCCC2CCCCC2)CC(=O)NOCc2ccccc2)nc1C(=O)O -US07320989B2,5,Cc1cc(Nc2cccc(C(=O)CCN3CCC(Cc4ccccc4)CC3)c2)c2ccccc2n1.OCCCO>>Cc1cc(Nc2cccc(C3(CCN4CCC(Cc5ccccc5)CC4)OCCCO3)c2)c2ccccc2n1 -US20130324518A1,9,BrC(Br)(Br)Br.CC(C)(C)[Si](C)(C)OCc1cc(CO)no1>>CC(C)(C)[Si](C)(C)OCc1cc(CBr)no1 -US20130090323A1,1,CC1(C)CCC(=O)NC1.Cc1c(Br)nc2cc(F)cc(F)c2c1Br>>Cc1c(N2CC(C)(C)CCC2=O)nc2cc(F)cc(F)c2c1Br -US20060135770A1,2,CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(CO)ccc2F)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(COS(C)(=O)=O)ccc2F)CC1 -US08426420B2,6,CCOC(=O)N1CCN(C(=O)[C@H](CCCCOCc2ccccc2)NC(=O)OCC2c3ccccc3-c3ccccc32)CC1>>CCOC(=O)N1CCN(C(=O)[C@@H](N)CCCCOCc2ccccc2)CC1 -US08735387B2,1,BrCCCBr.CCCOc1nc(Cc2ccc(Cl)cc2)nc2oc(-c3cc(C)c(O)c(C)c3)nc12>>CCCOc1nc(Cc2ccc(Cl)cc2)nc2oc(-c3cc(C)c(OCCCBr)c(C)c3)nc12 -US20120040954A1,1,CC(=O)N(C)C1CCNC1.O=Cc1ccc(F)cc1>>CC(=O)N(C)C1CCN(c2ccc(C=O)cc2)C1 -US08829040B2,1,CI.Cc1cc(F)c([N+](=O)[O-])cc1O>>COc1cc([N+](=O)[O-])c(F)cc1C -US20040092556A1,6,COC(=O)c1ccc(CN(Cc2ccccn2)C(=O)OC(C)(C)C)nc1>>CC(C)(C)OC(=O)N(Cc1ccccn1)Cc1ccc(C(=O)O)cn1 -US07569724B2,2,COC(=O)C=Cc1ccc(N)cc1.O=C(Cl)c1ccc2ccccc2c1>>COC(=O)C=Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1 -US20110009584A1,6,CC(=O)Oc1ccc(-c2nnc(-c3ccc(-c4nnc(-c5ccc(C(C)(C)C)cc5)o4)cc3)o2)cc1>>CC(C)(C)c1ccc(-c2nnc(-c3ccc(-c4nnc(-c5ccc(O)cc5)o4)cc3)o2)cc1 -US06897210B2,1,CN1CCCC(CO)C1.COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC1CCCN(C)C1 -US20070099950A1,1,CCN(CC)CCCC(N)C(C)C.Clc1c2ccccc2nc2ccccc12>>CCN(CC)CCCC(Nc1c2ccccc2nc2ccccc12)C(C)C -US20080287466A1,2,NC1=c2ccoc2=NCN1c1cccc(N)c1.O=C=NC1CCCCC1>>NC1=c2ccoc2=NCN1c1cccc(NC(=O)NC2CCCCC2)c1 -US20110207702A1,7,O=Cc1ccc(Sc2ccc(Cl)c(Cl)c2)cc1Br>>OCc1ccc(Sc2ccc(Cl)c(Cl)c2)cc1Br -US20150225422A1,1,O=S(=O)(c1cc(Br)cnc1Cl)N(CCO)C12CC(C1)C2>>O=S1(=O)c2cc(Br)cnc2OCCN1C12CC(C1)C2 -US04219483,7,CCCCCC(=O)/C=C/c1oc(C)cc(=O)c1OCCCCCC(=O)OCC>>CCCCCC(O)/C=C/c1oc(C)cc(=O)c1OCCCCCC(=O)OCC -US20120114696A1,7,CCOC(=O)C=Cc1cc(C(=O)Nc2cc(CCCCCCN3C(=O)c4ccccc4C3=O)c(OCCCCCCCN3C(=O)c4ccccc4C3=O)c(CCCCCCN3C(=O)c4ccccc4C3=O)c2)n(Cc2ccccc2)c1C#CC(O)(c1ccccc1)c1ccccc1>>CCOC(=O)CCc1cc(C(=O)Nc2cc(CCCCCCN3C(=O)c4ccccc4C3=O)c(OCCCCCCCN3C(=O)c4ccccc4C3=O)c(CCCCCCN3C(=O)c4ccccc4C3=O)c2)n(Cc2ccccc2)c1C#CC(O)(c1ccccc1)c1ccccc1 -US20100069381A1,2,NNC(=O)CCc1cccc(C(F)(F)F)c1.O=C(O)c1ccc2ncsc2c1>>O=C(CCc1cccc(C(F)(F)F)c1)NNC(=O)c1ccc2ncsc2c1 -US05863946,7,Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl>>Cc1ccc(Cl)c(Nc2ccccc2CO)c1Cl -US04957914,7,CC1CC2CCC=C3C=C(Cl)NC(=O)C1=C32>>CC1CC2CCC=C3C=C(Cl)NCC1=C32 -US08288549B2,1,N[C@@H](Cc1ccc(Oc2nccc3ccc(Br)cc23)cc1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1N[C@@H](Cc1ccc(Oc2nccc3ccc(Br)cc23)cc1)C(=O)O -US05201932,2,C1CCNCC1.COC(=O)c1c(C)noc1C(=O)O>>COC(=O)c1c(C)noc1C(=O)N1CCCCC1 -US20070265256A1,1,CN1CCNCC1=O.COc1cc2nncc(-c3ccc(F)nc3)c2cc1OC>>COc1cc2nncc(-c3ccc(N4CCN(C)C(=O)C4)nc3)c2cc1OC -US08580959B2,1,COc1cc([N+](=O)[O-])ccc1Cl.OC1CCNC1>>COc1cc([N+](=O)[O-])ccc1N1CC[C@@H](O)C1 -US20080027080A1,1,CO[C@@H]1CC[C@H](N2CC[C@H](N)C2=O)[C@H](CNC(C)=O)C1.FC(F)(F)c1ccc2ncnc(Cl)c2c1>>CO[C@@H]1CC[C@H](N2CC[C@H](Nc3ncnc4ccc(C(F)(F)F)cc34)C2=O)[C@H](CNC(C)=O)C1 -US20150210650A1,1,CC(C)(C)N.C[C@@H]1CC[C@@H](Nc2nc(Cl)ncc2C(N)=O)C[C@H]1O>>C[C@@H]1CC[C@@H](Nc2nc(NC(C)(C)C)ncc2C(N)=O)C[C@H]1O -US20020198388A1,1,CC(C)(C)OC(=O)Nc1cccc(Br)c1.CCI>>CCN(C(=O)OC(C)(C)C)c1cccc(Br)c1 -US20130225584A1,1,BrCc1ccccc1.CC(=O)c1cc(C)c(Br)cc1O>>CC(=O)c1cc(C)c(Br)cc1OCc1ccccc1 -US08476253B2,6,CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)CCCCCNc1ccc(C(=O)NCCCN(C)C(=O)OC(C)(C)C)cc1>>CNCCCNC(=O)c1ccc(NCCCCCC(=O)N(C)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)cc1 -US04477464,1,CN1CC(Cl)C(=O)Nc2ccccc21.O=C1NC(=O)c2ccccc21>>CN1CC(N2C(=O)c3ccccc3C2=O)C(=O)Nc2ccccc21 -US04226872,2,CC(C)C(Nc1ccc(C(F)(F)F)cc1Cl)C(=O)O.O=C(c1ccccc1)c1cccc(CO)n1>>CC(C)C(Nc1ccc(C(F)(F)F)cc1Cl)C(=O)OCc1cccc(C(=O)c2ccccc2)n1 -US20130289033A1,2,NCCc1c[nH]c2ccc(Cl)cc12.O=C(Cl)c1cccc(I)c1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1 -US20120232056A1,6,COC(=O)c1ccc2nc(-c3ccc4[nH]nnc4c3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc2[nH]nnc2c1 -US20140235863A1,4,NC(=S)NN=C1CCN(Cc2ccccc2)CC1.O=C(CBr)c1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(-c2csc(NN=C3CCN(Cc4ccccc4)CC3)n2)c1 -US20040259888A1,1,CN1CCNCC1.Fc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1>>CN1CCN(c2ncnc3oc(-c4ccccc4)c(-c4ccc(F)cc4)c23)CC1 -US20150266916A1,7,CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCC(F)(F)F)cc3)c2)O[C@](C=O)(CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCC(F)(F)F)cc3)c2)OC(CO)(CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US07807671B2,4,CSc1nc(N)n(-c2ccccc2)n1.ClCCNCCCl>>CSc1nc(N2CCNCC2)n(-c2ccccc2)n1 -US20120225854A1,2,O=C1CNCCN1.O=S(=O)(Cl)c1ccc(Cl)nc1>>O=C1CN(S(=O)(=O)c2ccc(Cl)nc2)CCN1 -US20050101063A1,3,C#C[Si](C)(C)C.COC(=O)c1ccc(I)cc1>>COC(=O)c1ccc(C#C[Si](C)(C)C)cc1 -US20110319439A1,1,COc1cc(B(O)O)ccc1OCC(C)(C)O.O=c1cc(Cl)nc[nH]1>>COc1cc(-n2cnc(Cl)cc2=O)ccc1OCC(C)(C)O -US06124297,1,CN.ClCc1cccnc1>>CNCc1cccnc1 -US20090143592A1,1,COC(=O)c1ccc(CN)cc1.O=C1CCC2(CCCCC2)CC1>>COC(=O)c1ccc(CNC2CCC3(CCCCC3)CC2)cc1 -US08822471B2,1,N#Cc1ccc(Cl)nc1.O=C(c1ccc(-c2cnco2)cc1)N(C1CCNCC1)C1CC1>>N#Cc1ccc(N2CCC(N(C(=O)c3ccc(-c4cnco4)cc3)C3CC3)CC2)nc1 -US20140154179A1,6,CCOC(=O)c1ccn(-c2ccc(Cl)c(F)c2)n1>>O=C(O)c1ccn(-c2ccc(Cl)c(F)c2)n1 -US20120077979A1,3,Cc1cc(-c2ccccc2)nc2cc(B3OC(C)(C)C(C)(C)O3)ccc12.Nc1nccn2c(C3CCC(CO)CC3)nc(I)c12>>Cc1cc(-c2ccccc2)nc2cc(-c3nc([C@@H]4CC[C@@H](CO)CC4)n4ccnc(N)c34)ccc12 -US20100137303A1,3,CN(C)CCOc1ncc(N)cc1Br.COc1ncc(B(O)O)cn1>>COc1ncc(-c2cc(N)cnc2OCCN(C)C)cn1 -US20100168076A1,1,COc1cncc(-c2ccc(C(C)(c3ccc(/C(N)=N\OC(=O)COC(C)=O)cn3)C(C)C)cc2)c1>>COc1cncc(-c2ccc(C(C)(c3ccc(-c4noc(COC(C)=O)n4)cn3)C(C)C)cc2)c1 -US20150210720A1,6,CC(C)(COc1nc(N2CCOCC2)ccc1NC(=O)c1coc2c1C(=O)NCC2)OCc1ccccc1>>CC(C)(O)COc1nc(N2CCOCC2)ccc1NC(=O)c1coc2c1C(=O)NCC2 -US20020183371A1,2,Nc1ccc2[nH]ncc2c1.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc2[nH]ncc2c1)OCc1ccccc1 -US07704995B2,9,[N-]=[N+]=NC1CCc2cc(-c3cccs3)ccc21>>NC1CCc2cc(-c3cccs3)ccc21 -US07071173B2,2,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.Nc1nc2c(ncn2[C@H]2C[C@H](F)[C@@H](COC(=O)CCC(=O)OC(CO)CO)O2)c(=O)[nH]1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(CO)OC(=O)CCC(=O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@@H]1F -US07652015B2,2,CC(C)(C)OC(=O)N1CCN(c2ccc(N)cn2)CC1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)nc2)cc1 -US20110105758A1,7,O=C(O)C1=C(c2ccccc2)CCCC1>>O=C(O)C1CCCCC1c1ccccc1 -US20140228579A1,2,NCc1ccccc1.O=C(Cl)c1ccco1>>O=C(NCc1ccccc1)c1ccco1 -US08344135B2,6,CCC(=O)Nc1nc2ccc(Oc3cc(NC(=O)OC(C)(C)C)c(F)cc3Cl)nc2s1>>CCC(=O)Nc1nc2ccc(Oc3cc(N)c(F)cc3Cl)nc2s1 -US20090221555A1,1,COCC(COC)N1CCc2cc(N)c(OC)cc2CC1.CS(=O)(=O)N[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl>>COCC(COC)N1CCc2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)c(OC)cc2CC1 -US06528528B2,2,Nc1cc(C(=O)Nc2ccccc2)ccc1F.S=C=Nc1cc(Cl)cc(Cl)c1>>O=C(Nc1ccccc1)c1ccc(F)c(NC(=S)Nc2cc(Cl)cc(Cl)c2)c1 -US20080300136A1,2,CCOC(=O)c1csc(N)n1.O=C(Cl)c1ccccc1Cl>>CCOC(=O)c1csc(NC(=O)c2ccccc2Cl)n1 -US08404708B2,6,CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N[C@@H]2CCC[C@H]2OCc2ccccc2)cc1-c1ccccc1Cl>>CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N[C@@H]2CCC[C@H]2O)cc1-c1ccccc1Cl -US20080300242A1,1,CCOc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F.COc1cc(C2CCN(CC(C)C)CC2)ccc1N>>CCOc1ccc(-c2nc3ccccn3c2-c2ccnc(Nc3ccc(C4CCN(CC(C)C)CC4)cc3OC)n2)cc1C(=O)Nc1c(F)cccc1F -US07034166B2,1,C[C@H](N)c1ccccc1.Cc1ccc(C2c3c(C)c(Br)c(C)c(C)c3OC2(C)C)cc1>>Cc1ccc(C2c3c(C)c(N[C@@H](C)c4ccccc4)c(C)c(C)c3OC2(C)C)cc1 -US20110263598A1,3,COc1ccc2c(c1)CC(=O)N2.C[Si](C)(C)CCOCn1nc(-c2ccc(N3CCOCC3)nc2)c2ccc(C=O)cc21>>COc1ccc2c(c1)/C(=C\c1ccc3c(-c4ccc(N5CCOCC5)nc4)nn(COCC[Si](C)(C)C)c3c1)C(=O)N2 -US08586751B2,1,COC(=O)c1ccc(N)cc1.NC(=O)c1ccc(Cl)nc1Cl>>COC(=O)c1ccc(Nc2nc(Cl)ccc2C(N)=O)cc1 -US08569535B2,1,CCCBr.COC(=O)C1Cc2cc(Br)ccc2CN1C(=O)c1cccc(C)c1O>>CCCOc1c(C)cccc1C(=O)N1Cc2ccc(Br)cc2CC1C(=O)OC -US20050054800A1,3,O=Cc1cccc(Br)n1.OB(O)c1cccc2ccccc12>>O=Cc1cccc(-c2cccc3ccccc23)n1 -US05668147,6,O=C(OCc1ccccc1)N1C[C@@H](C(F)(F)F)[C@H](CN2C(=O)c3ccccc3C2=O)C1>>NC[C@@H]1CN(C(=O)OCc2ccccc2)C[C@H]1C(F)(F)F -US20110021479A1,2,CC(C)(C)OC(=O)N1CCCC(CN)C1.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>CC(C)(C)OC(=O)N1CCCC(CNC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C1 -US04939165,3,CC(C)Cl.c1ccc(-c2ccc(-c3cccs3)s2)cc1>>CC(C)c1ccc(-c2ccc(-c3ccccc3)s2)s1 -US20120208815A1,1,CC(C)(C)OC(=O)NC1CCNCC1.COc1ccc(Cl)c([N+](=O)[O-])c1>>COc1ccc(N2CCC(NC(=O)OC(C)(C)C)CC2)c([N+](=O)[O-])c1 -US20150232469A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(F)cc2F)CC1 -US05972975,2,CC(=O)OC(C)=O.Cc1cc(N)nc(CCCCN)c1>>CC(=O)NCCCCc1cc(C)cc(N)n1 -US20010008893A1,2,COc1c(O)cc(C)c(O)c1OC.O=C(Cl)c1ccccc1>>COc1c(O)cc(C)c(OC(=O)c2ccccc2)c1OC -US05262412,2,CCCCc1nn(-c2cc([N+](=O)[O-])ccc2C(F)(F)F)c(C#N)c1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1F.O=C(O)c1ccccc1Cl>>CCCCc1nn(-c2cc([N+](=O)[O-])ccc2C(F)(F)F)c(C#N)c1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1F -US08853210B2,2,CN(C)S(=O)(=O)Cl.c1ccc(C[C@H]2CN2)cc1>>CN(C)S(=O)(=O)N1CC1Cc1ccccc1 -US05859014,4,ClCCNCCCl.Nc1ccccc1OCC(F)(F)F>>FC(F)(F)COc1ccccc1N1CCNCC1 -US05843957,1,COc1cccc(-c2c(NC(=O)Nc3c(C(C)C)cccc3C(C)C)c(=O)[nH]c3ncccc23)c1.O=C1c2ccccc2C(=O)N1CCCBr>>COc1cccc(-c2c(NC(=O)Nc3c(C(C)C)cccc3C(C)C)c(=O)n(CCCN3C(=O)c4ccccc4C3=O)c3ncccc23)c1 -US06127414,1,O=C(O)C(c1ccccc1)c1ccccc1.O=[N+]([O-])c1ccccc1O>>O=C(Oc1ccccc1[N+](=O)[O-])C(c1ccccc1)c1ccccc1 -US20060223826A1,2,C[C@@H](c1c[nH]c2ccccc12)[C@@H](NC(=O)N1CCNCC1)C(=O)Nc1cccc(CN(C)C)c1.O=C(O)C1CCCCC1>>C[C@@H](c1c[nH]c2ccccc12)[C@@H](NC(=O)N1CCN(C(=O)C2CCCCC2)CC1)C(=O)Nc1cccc(CN(C)C)c1 -US08765730B2,3,CON(C)C(=O)CC(c1ccc(Br)cc1)c1ccc(F)cc1C.Cc1cc(Br)ccn1>>Cc1cc(C(=O)CC(c2ccc(Br)cc2)c2ccc(F)cc2C)ccn1 -US20050239818A1,8,COc1ccc(C2CCC(O)CC2NC(=O)c2ccc(OCC3CC3)c(OCC3CC3)c2)cc1OC>>COc1ccc(C2CCC(=O)CC2NC(=O)c2ccc(OCC3CC3)c(OCC3CC3)c2)cc1OC -US04678803,1,CS(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=[N+]([O-])OC1COc2c(O)cccc2C1>>CS(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)Oc1cccc2c1OC[C@H](O[N+](=O)[O-])C2 -US05439932,7,COC(=O)/C=C/C=C/c1ccsc1>>OC/C=C/C=C/c1ccsc1 -US20090216014A1,1,CN1CCNCC1.CS(=O)(=O)OCc1cc(=O)c(OCCCCCOc2ccnc3cc(C(F)(F)F)ccc23)co1>>CN1CCN(Cc2cc(=O)c(OCCCCCOc3ccnc4cc(C(F)(F)F)ccc34)co2)CC1 -US20150057265A1,1,CC(C)(C)OC(=O)Nc1oc2cc(C=O)cnc2c1C(=O)Nc1cnccc1N1C[C@H](C(F)(F)F)C[C@H](NC(=O)OC(C)(C)C)C1.CN1CCNCC1>>CN1CCN(Cc2cnc3c(C(=O)Nc4cnccc4N4C[C@H](C(F)(F)F)C[C@H](NC(=O)OC(C)(C)C)C4)c(NC(=O)OC(C)(C)C)oc3c2)CC1 -US05352690,1,CC(C)I.CCc1cc(O)c(OCc2ccccc2)cc1OCCCCCC(C)(C)C#N>>CCc1cc(OC(C)C)c(OCc2ccccc2)cc1OCCCCCC(C)(C)C#N -US20060135551A1,9,CCC1C(C(=O)OC)C(=O)c2cc(C)nc(C)c2N1C(=O)OCc1ccccc1>>CCC1CC(=O)c2cc(C)nc(C)c2N1C(=O)OCc1ccccc1 -US20120285538A1,3,CCCCC1(CCCC)c2cc(Br)ccc2-c2ccc(N3CCCCC3)cc21.CN(C)C=O>>CCCCC1(CCCC)c2cc(C=O)ccc2-c2ccc(N3CCCCC3)cc21 -US08691822B2,1,C=C(C)Cc1c(C(=O)OC)ccc([N+](=O)[O-])c1O>>COC(=O)c1ccc([N+](=O)[O-])c2c1CC(C)(C)O2 -US05387684,1,Cc1ccc([N+](=O)[O-])c(C=O)c1.N#Cc1ccccc1N>>Cc1ccc([N+](=O)[O-])c(C=Nc2ccccc2C#N)c1 -US05612377,1,BrCC1CCCCC1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCC2CCCCC2)cc1 -US20150239884A1,3,CC(C)(C)[Si](OCCn1cc(I)cn1)(c1ccccc1)c1ccccc1.COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1N>>COc1cc(-c2cnn(CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c2)ccc1N -US06127414,6,CC(C)(C)OC(=O)N[C@H](CCCNC(=O)OCc1ccccc1)C(=O)N[C@@H](CO)c1ccccc1>>N[C@H](CCCNC(=O)OCc1ccccc1)C(=O)N[C@@H](CO)c1ccccc1 -US08278482B2,2,CC(C)(CC(=O)Cl)N=[N+]=[N-].CCCCNC>>CCCCN(C)C(=O)CC(C)(C)N=[N+]=[N-] -US20100331397A1,7,CO[C@@H]1[C@@H](/C=C/P(=O)(OC)OC)O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@@H]1O[Si](C)(C)C(C)(C)C>>CO[C@@H]1[C@@H](CCP(=O)(OC)OC)O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@@H]1O[Si](C)(C)C(C)(C)C -US20060128750A1,3,Brc1cccnc1.CN(C)C=O>>O=Cc1ccncc1Br -US20060004046A1,1,CC(C)S.N#Cc1cnc2ccc(I)cc2c1Cl>>CC(C)Sc1c(C#N)cnc2ccc(I)cc12 -US05741800,1,C1CNCCN1.ClCCCc1ccccc1>>c1ccc(CCCN2CCNCC2)cc1 -US08497371B2,2,CCn1cc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc21.FC(F)(F)c1cccc(N=C=S)c1>>CCn1cc(C(=O)O)c(=O)c2cnc(N3CCN(C(=S)Nc4cccc(C(F)(F)F)c4)CC3)nc21 -US20110105470A1,2,O=C(Cl)c1ccc(-n2cccn2)cc1.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccccc2C2=C1SCC1(CCN(C(=O)c3ccc(-n4cccn4)cc3)CC1)O2 -US20140243302A1,6,O=c1[nH]c(/C=C/c2ccccc2)ncc1OC1CCCCO1>>O=c1[nH]c(/C=C/c2ccccc2)ncc1O -US20120214767A1,1,CC(C)(C)OC(=O)C1CNC1.COC(=O)c1noc2c1CCc1cc(C=O)ccc1-2>>COC(=O)c1noc2c1CCc1cc(CN3CC(C(=O)OC(C)(C)C)C3)ccc1-2 -US20070043076A1,3,COc1ccc(C=O)cc1Br.O=C(CC(=O)Nc1cccc(C(F)(F)F)c1)Nc1cccc(C(F)(F)F)c1>>COc1ccc(C=C(C(=O)Nc2cccc(C(F)(F)F)c2)C(=O)Nc2cccc(C(F)(F)F)c2)cc1Br -US07754886B2,3,Brc1ccc(I)cc1.CC1(C)OB(c2ccc(C(=O)NS(=O)(=O)c3ccc(NC4CCCCC4)c([N+](=O)[O-])c3)cc2)OC1(C)C>>O=C(NS(=O)(=O)c1ccc(NC2CCCCC2)c([N+](=O)[O-])c1)c1ccc(-c2ccc(Br)cc2)cc1 -US06043240,1,CCOC(=O)CCBr.Fc1ccc2c(N3CCNCC3)nsc2c1>>CCOC(=O)CCN1CCN(c2nsc3cc(F)ccc23)CC1 -US08063061B2,4,Cn1c(=O)c(-c2ccc(F)cc2)cc2c3cc(C(=O)CBr)ccc3n(C)c21.NC(N)=S>>Cn1c(=O)c(-c2ccc(F)cc2)cc2c3cc(-c4csc(N)n4)ccc3n(C)c21 -US20090247474A1,9,O=C(c1cnc(C2(Cl)CCC3(CC2)OCCO3)s1)N1CCCC1>>O=C(c1cnc(C2CCC3(CC2)OCCO3)s1)N1CCCC1 -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1.O=C(CCCCCBr)c1ccc2c(c1)OCO2>>COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCCCC(=O)c2ccc3c(c2)OCO3)CC1 -US20130324518A1,2,CCOCC1CCN(Cc2ccc(COc3cccc4c3CN(C(CCC(=O)OC)C(N)=O)C4=O)cc2)CC1>>CCOCC1CCN(Cc2ccc(COc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)cc2)CC1 -US20130253002A1,7,C=C(C)c1cnc2c(N)nc3ccccc3c2c1>>CC(C)c1cnc2c(N)nc3ccccc3c2c1 -US20120289505A1,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4cccnc4Cl)cc3)cc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NC(=O)c4cccnc4Cl)cc3)cc2C1=O -US20110082158A1,6,COC(=O)c1cc(CCCc2cc3c(=O)[nH]c(N)nc3[nH]2)cs1>>Nc1nc2[nH]c(CCCc3csc(C(=O)O)c3)cc2c(=O)[nH]1 -US20140234254A1,3,C#CC(C)O.COc1ncc(-c2ccn3ncc(I)c3n2)cc1NS(=O)(=O)c1ccc(F)cc1F>>COc1ncc(-c2ccn3ncc(C#CC(C)O)c3n2)cc1NS(=O)(=O)c1ccc(F)cc1F -US20110098296A1,2,CCOC(=O)c1cccc(N)c1.O=C(Cl)c1c(F)cccc1F>>CCOC(=O)c1cccc(NC(=O)c2c(F)cccc2F)c1 -US04518597,1,CC1(C)OC(=O)Nc2ccc(OCCCCCl)cc21.Cc1cc(C)nc(S)n1>>Cc1cc(C)nc(SCCCCOc2ccc3c(c2)C(C)(C)OC(=O)N3)n1 -US20020183371A1,9,[N-]=[N+]=NC[C@@H]1CN(c2ccc(SC(c3ccccc3)(c3ccccc3)c3ccccc3)c(F)c2)C(=O)O1>>NC[C@H]1CN(c2ccc(SC(c3ccccc3)(c3ccccc3)c3ccccc3)c(F)c2)C(=O)O1 -US04743587,2,CCOC(=O)CC(CC(C)C)C(=O)O.CNC(=O)[C@@H](N)Cc1ccc(OC)cc1>>CCOC(=O)CC(CC(C)C)C(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)NC -US08377923B2,6,CCOC(=O)C(C)(C)Oc1ccc(F)cc1F>>CC(C)(Oc1ccc(F)cc1F)C(=O)O -US20020052322A1,2,COCC(N)C(=O)OC.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>COCC(NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1)C(=O)OC -US20080004302A1,1,CI.COC(=O)c1cc(C)cc(O)c1>>COC(=O)c1cc(C)cc(OC)c1 -US20130045962A1,1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)c1nc(Cl)nc(Cl)c1F.C[C@@H]1CN(C)CCN1>>C[C@@H]1CN(C)CCN1c1nc(Cl)nc(N(C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1F -US04618627,1,BrCCCCCCCCCCCCBr.OCc1ccccc1>>BrCCCCCCCCCCCCOCc1ccccc1 -US20120178736A1,1,CNc1nc2ccccc2[nH]1.Cn1c(CN2CCN(C(C)(C)C)CC2)nc2c(N3CCOCC3)nc(Cl)nc21>>CNc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(C)(C)C)CC3)n(C)c2n1 -US20110212956A1,2,CC(=O)OC(C)=O.NCCc1cccc2c1OCCO2>>CC(=O)NCCc1cccc2c1OCCO2 -US20140005168A1,3,CCCC[Sn](CCCC)(CCCC)c1cc2c(cn1)cnn2-c1cccc(N2CCCN(C(=O)OC(C)(C)C)CC2)n1.Cc1nc(Br)cnc1N>>Cc1nc(-c2cc3c(cn2)cnn3-c2cccc(N3CCCN(C(=O)OC(C)(C)C)CC3)n2)cnc1N -US20130216497A1,1,CCOC(=O)c1cnc2c(ccn2S(=O)(=O)c2ccc(C)cc2)c1Cl.NC1CCCCC1>>CCOC(=O)c1cnc2c(ccn2S(=O)(=O)c2ccc(C)cc2)c1NC1CCCCC1 -US07851473B2,2,CC(=O)Cl.CNc1ccc([N+](=O)[O-])cc1>>CC(=O)N(C)c1ccc([N+](=O)[O-])cc1 -US07935721B2,6,CC1(C)COc2cc3c(cc21)C1(CO3)C(=O)N(C(c2ccccc2)c2ccccc2)c2ccccc21>>CC1(C)COc2cc3c(cc21)C1(CO3)C(=O)Nc2ccccc21 -US20130324515A1,3,CC(C)(C)OC(=O)C1(c2ccc(Br)cc2)CC1.CC1(C)OB(c2cnc(N)nc2)OC1(C)C>>CC(C)(C)OC(=O)C1(c2ccc(-c3cnc(N)nc3)cc2)CC1 -US20070179126A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)C2CCCCN2C(=O)OCc2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCN(C(=O)C2CCCCN2)CC1 -US20120309966A1,1,O=C(OCc1ccccc1)N1CCNCC1.O=C1CCC(C(=O)NCc2nccnc2Cl)CC1>>O=C(NCc1nccnc1Cl)C1CCC(N2CCN(C(=O)OCc3ccccc3)CC2)CC1 -US04877804,1,CCOc1nnc(C(C)Br)s1.Oc1ccc(Oc2ccccn2)cc1>>CCOc1nnc(C(C)Oc2ccc(Oc3ccccn3)cc2)s1 -US05411989,2,N[C@@H]1CC[C@@H](O[N+](=O)[O-])CC1.O=C1CC[C@@H](C(=O)O)N1>>O=C1CC[C@@H](C(=O)N[C@@H]2CC[C@@H](O[N+](=O)[O-])CC2)N1 -US20140288044A1,1,CN(CCO)c1ccc(N)cn1.N#Cc1cc(-c2ccnc(Cl)n2)ccc1OC1CCOCC1>>CN(CCO)c1ccc(Nc2nccc(-c3ccc(OC4CCOCC4)c(C#N)c3)n2)cn1 -US20020161150A1,3,COCCCCCl.O=CC1CC2C=CC1C2>>COCCCCC(O)C1CC2C=CC1C2 -US08022192B2,2,CC(=O)OC(C)=O.Cc1ccc(Cc2c(C)[nH][nH]c2=O)cc1F>>CC(=O)n1[nH]c(=O)c(Cc2ccc(C)c(F)c2)c1C -US20130072679A1,3,CC(C)(C)OC(=O)N1C=C(B2OC(C)(C)C(C)(C)O2)CCC1.CN1C(=O)CCc2cc(-c3cncc(Br)c3)ccc21>>CN1C(=O)CCc2cc(-c3cncc(C4=CN(C(=O)OC(C)(C)C)CCC4)c3)ccc21 -US20030158178A1,9,CCCCCC(C=C(Br)Br)c1ccc2c(c1)N(C(=O)OC(C)(C)C)CCC2(C)C>>C#CC(CCCCC)c1ccc2c(c1)N(C(=O)OC(C)(C)C)CCC2(C)C -US20060264460A1,1,CCOC(CBr)OCC.c1c[nH]cn1>>CCOC(Cn1ccnc1)OCC -US20120316147A1,3,O=C(O)c1cccc(Br)n1.OB(O)C1=CCCCC1>>O=C(O)c1cccc(C2=CCCCC2)n1 -US20140200231A1,6,COC(=O)CCCOc1cn[nH]n1>>O=C(O)CCCOc1cn[nH]n1 -US20130203986A1,1,CN.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CNc1nc(Cl)ncc1[N+](=O)[O-] -US20150011527A1,2,CC(C)(C)OC(=O)[C@H](Cc1ccc(-c2ncc(C(=O)O)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)cc1.CCCCCCC(=O)NN>>CCCCCCC(=O)NNC(=O)c1cnc(-c2ccc(C[C@H](NC(=O)c3ccc(C(C)(C)C)cc3)C(=O)OC(C)(C)C)cc2)nc1 -US20140005133A1,7,CCOC(=O)c1cc(-c2ccccn2)no1>>OCc1cc(-c2ccccn2)no1 -US06358973B1,7,COc1cccc(C(C#N)CC(C)C)c1>>COc1cccc(C(CN)CC(C)C)c1 -US20050234106A1,1,CCN.Clc1nc(NCC2(c3ccccc3)CCCCC2)c2ccccc2n1>>CCNc1nc(NCC2(c3ccccc3)CCCCC2)c2ccccc2n1 -US20150087646A1,2,COC(=O)c1ccc(-n2nc(-c3c(Cl)cccc3Cl)[nH]c2=O)cc1OC.Nc1cc(C(F)(F)F)ccc1F>>COc1cc(-n2nc(-c3c(Cl)cccc3Cl)[nH]c2=O)ccc1C(=O)Nc1cc(C(F)(F)F)ccc1F -US20120232283A1,6,COC(=O)c1cccc([N+](=O)[O-])c1N(Cc1ccc(-c2ccccc2-c2nnnn2Cc2ccccc2)cc1)C(=O)OC(C)(C)C>>COC(=O)c1cccc([N+](=O)[O-])c1NCc1ccc(-c2ccccc2-c2nnnn2Cc2ccccc2)cc1 -US20040002497A1,7,CC(C)Cn1nc(-c2ccccc2)cc(C(=O)O)c1=O>>CC(C)Cn1nc(-c2ccccc2)cc(CO)c1=O -US04336268,1,CNC.COc1cccc(C2(CCCl)C=CCCC2)c1>>COc1cccc(C2(CCN(C)C)C=CCCC2)c1 -US20120010191A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1cc(Br)cc(Nc2ccncn2)c1=O>>Cn1cc(B2OC(C)(C)C(C)(C)O2)cc(Nc2ccncn2)c1=O -US08461185B2,2,C[C@@H](N)c1ccc(F)cn1.Cc1ccc(-c2cc(C(=O)O)cc(C3=NO[C@H](c4ccccn4)C3)c2)nc1>>Cc1ccc(-c2cc(C(=O)N[C@H](C)c3ccc(F)cn3)cc(C3=NO[C@H](c4ccccn4)C3)c2)nc1 -US08507502B2,6,CC(C)(C)OC(=O)N1CCc2c(sc3ncnc(NC(CO)c4ccccc4)c23)C1>>OCC(Nc1ncnc2sc3c(c12)CCNC3)c1ccccc1 -US07109214B2,7,CN(C)CC1CC(c2ccc(S(C)(=O)=O)cc2)=C(c2ccc(C(C)(C)C)cc2)C1=O>>CN(C)CC1CC(c2ccc(S(C)(=O)=O)cc2)=C(c2ccc(C(C)(C)C)cc2)C1O -US20120238549A1,7,O=C1C=C2CCCc3cc(O)ccc3C2(Cc2ccccc2)CC1>>O=C1CCC2(Cc3ccccc3)c3ccc(O)cc3CCCC2C1 -US20070197551A1,2,CC(CCCC(=O)O)N1CCN(c2ccc3ccccc3n2)CC1.CCOC(=O)C1=C(N)CCCC1>>CCOC(=O)C1=C(NC(=O)CCCC(C)N2CCN(c3ccc4ccccc4n3)CC2)CCCC1 -US20040208844A1,2,CC(C)(C)OC(=O)NCCCC(=O)O.NCc1nc2ccccc2[nH]1>>CC(C)(C)OC(=O)NCCCC(=O)NCc1nc2ccccc2[nH]1 -US20100280016A1,3,COC(=O)c1ccc2c(c1)OCCC2=O.O=Cc1ccc(F)cc1>>COC(=O)c1ccc2c(c1)OCC(=Cc1ccc(F)cc1)C2=O -US05998433,3,C=O.CNC.O=C(CCCCS(=O)(=O)c1ccccc1)N1CCc2ccoc2C1>>CN(C)Cc1cc2c(o1)CN(C(=O)CCCCS(=O)(=O)c1ccccc1)CC2 -US07951824B2,9,NC(=O)Cc1csc(N)n1>>N#CCc1csc(N)n1 -US20140275070A1,9,COC(=O)c1cc2c(OC)c(C)ccc2[nH]1.N>>COc1c(C)ccc2[nH]c(C(N)=O)cc12 -US20150239894A1,1,CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2ccc(Nc3cncnc3)cc12.CC(C)(C)C(=O)OCCl>>CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2ccc(N(COC(=O)C(C)(C)C)c3cncnc3)cc12 -US20120101083A1,2,CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)cc1C#N.C[C@@H](O)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCN(C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)O)CC4)no2)cc1C#N -US20150183802A1,9,Oc1cccc2cc(Br)c(F)cc12.[C-]#N>>N#Cc1cc2cccc(O)c2cc1F -US20100041892A1,2,CCCCCC(=O)Cl.CCCCOc1cc(CCS(N)(=O)=O)n(Cc2ccc(Cl)cc2Cl)n1>>CCCCCC(=O)NS(=O)(=O)CCc1cc(OCCCC)nn1Cc1ccc(Cl)cc1Cl -US05142064,1,COCCl.O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(Cl)cc1>>COCN(C(=O)Nc1ccc(Cl)cc1)C(=O)c1c(Cl)cccc1Cl -US06087380,2,CCCCCCCCOC(=O)Cl.CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1ccccc1>>CCCCCCCCOC(=O)NC(=N)c1ccc(NCc2nc3cc(C(=O)N(CCC(=O)OCC)c4ccccc4)ccc3n2C)cc1 -US06265411B1,3,O=C1Cc2ccc(Br)cc2N1.OB(O)c1ccccc1>>O=C1Cc2ccc(-c3ccccc3)cc2N1 -US04087432,1,CS.On1c(C(F)(F)C(F)(F)F)nc2nc(Cl)ccc21>>CSc1ccc2c(n1)nc(C(F)(F)C(F)(F)F)n2O -US20090275590A1,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccn1.Cc1ccc(Br)nc1>>COc1cc(-c2ccc(C)cn2)ccn1 -US20140349993A1,2,CC1(C)OCC(COc2cccc(N)n2)O1.O=C(O)c1cnc2ccc(-c3ccccc3C(F)(F)F)nn12>>CC1(C)OCC(COc2cccc(NC(=O)c3cnc4ccc(-c5ccccc5C(F)(F)F)nn34)n2)O1 -US20090306197A1,7,CC(C)c1cc2c(c(-c3ccc(F)cc3)c1C(O)c1ccc(OC(F)(F)F)cc1)C(=O)CC(C)(C)O2>>CC(C)c1cc2c(c(-c3ccc(F)cc3)c1[C@H](O)c1ccc(OC(F)(F)F)cc1)[C@@H](O)CC(C)(C)O2 -US05073646,5,CC1(CN)CN(C(c2ccccc2)c2ccccc2)C1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC1(CNC(=O)C(F)(F)F)CN(C(c2ccccc2)c2ccccc2)C1 -US20070049581A1,6,CCOC(=O)CCC1CCN(C2CCN(C(=O)[C@@H](Cc3cc(Cl)c(N)c(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1>>Nc1c(Cl)cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCC(CCC(=O)O)CC3)CC2)cc1C(F)(F)F -US20110053933A1,1,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(O)CC1.Cc1nccnc1O>>Cc1nccnc1OC1CCN(C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)CC1 -US04202893,1,CCOC(=O)C(=NOC)c1csc(N)n1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)C(=NOC)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US20110190278A1,6,CCC(=O)NCCN1C(=O)C2(CCC2)Sc2cc(C)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc21>>CCC(=O)NCCN1C(=O)C2(CCC2)Sc2cc(C)c(C(=O)N(C(C)C)[C@@H]3CCCNC3)cc21 -US07790898B2,2,COc1cccc(C2(O)CCCNC2)c1.O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1>>COc1cccc(C2(O)CCCN(C(=O)c3ccc(Cl)c([N+](=O)[O-])c3)C2)c1 -US20100331298A1,9,O=C1COc2ccc(C(O)CN3CCC(CC4CC4)(C(=O)NCc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)cc2N1>>O=C1COc2ccc(CCN3CCC(CC4CC4)(C(=O)NCc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)cc2N1 -US08765940B2,1,Cc1c(N2CCOC(C)(C)C2)nc2cc(F)cc(F)c2c1Cl.c1nc2c(cc1N1CCOCC1)NCC21CCOCC1>>Cc1c(N2CCOC(C)(C)C2)nc2cc(F)cc(F)c2c1N1CC2(CCOCC2)c2ncc(N3CCOCC3)cc21 -US20110009454A1,2,NCc1ccc(CCc2ccccc2)cc1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1ccc(CCc2ccccc2)cc1 -US20050014767A1,7,O=C1NC(=O)C(=Cc2ccc(-c3cc(C4CCCCC4)c(O)c([N+](=O)[O-])c3)nc2)S1>>Nc1cc(-c2ccc(C=C3SC(=O)NC3=O)cn2)cc(C2CCCCC2)c1O -US20150038528A1,7,CC(C)(C)OC(=O)C(C#N)c1ccccc1>>CC(C)(C)OC(=O)C(CN)c1ccccc1 -US04205085,6,CCOC(=O)CNC(=O)c1ccc(NCCCCCCCCCCCCCCCC(F)(F)F)cc1>>O=C(O)CNC(=O)c1ccc(NCCCCCCCCCCCCCCCC(F)(F)F)cc1 -US20140057893A1,1,CC1(OC(=O)N2CCC([C@H]3C[C@H]3CCO)CC2)CC1.COC(=O)Cc1ccc(O)cc1F>>COC(=O)Cc1ccc(OCC[C@@H]2C[C@@H]2C2CCN(C(=O)OC3(C)CC3)CC2)cc1F -US20140135318A1,2,CCOC(=O)c1nn(-c2ccc(C(=O)O)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Cl.NS(=O)(=O)c1ccc2ccc(I)cc2c1>>CCOC(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccc(I)cc4c3)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Cl -US20090221645A1,2,CNOC.Cc1cc(C(=O)O)ccc1Br>>CON(C)C(=O)c1ccc(Br)c(C)c1 -US08809538B2,9,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.N>>CC(C)(C)OC(=O)N1CCC(C)(C(N)=O)CC1 -US20030195221A1,1,CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2.FC(F)(F)c1cccc(-c2c(-c3ccnc(Cl)c3)nc(Cl)n3cnnc23)c1>>CC(C)(C)OC(=O)N1CC2C[C@@H]1CN2c1nc(-c2ccnc(Cl)c2)c(-c2cccc(C(F)(F)F)c2)c2nncn12 -US07087601B2,1,CC(C)(C)[Si](C)(C)OCCBr.Cc1ccc(-c2nc3ccccc3o2)cc1O>>Cc1ccc(-c2nc3ccccc3o2)cc1OCCO[Si](C)(C)C(C)(C)C -US20110178053A1,3,COc1cncc(B2OC(C)(C)C(C)(C)O2)c1.O=S(=O)(Oc1cc2c(cn1)[nH]c1ncc(F)cc12)C(F)(F)F>>COc1cncc(-c2cc3c(cn2)[nH]c2ncc(F)cc23)c1 -US07560558B2,1,COc1cc2nccc(Cl)c2cc1OC.Sc1ccc2ccccc2n1>>COc1cc2nccc(Sc3ccc4ccccc4n3)c2cc1OC -US06462055B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(Cl)c(O)c(Cl)c1>>CC(C)(C)OC(=O)Nc1cc(Cl)c(O)c(Cl)c1 -US20090082311A1,1,CC(=O)NC(CCc1ccc(-c2ccc(Br)cc2F)cc1Cl)(COC(C)=O)COC(C)=O.Cc1ccc(S)cc1>>CC(=O)NC(CCc1ccc(-c2ccc(Sc3ccc(C)cc3)cc2F)cc1Cl)(COC(C)=O)COC(C)=O -US20060270656A1,9,CC(C)c1nc(C(N)=O)cs1>>CC(C)c1nc(C#N)cs1 -US20100184815A1,2,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)O)cc1.OCc1cn(Cc2ccc(SC(F)(F)F)cc2)nn1>>CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)OCc2cn(Cc3ccc(SC(F)(F)F)cc3)nn2)cc1 -US20130123235A1,6,COC(=O)c1c(N)ccc(Br)c1O>>Nc1ccc(Br)c(O)c1C(=O)O -US07649001B2,4,BrCCCCCBr.N#Cc1ccc(N)c2ccccc12>>N#Cc1ccc(N2CCCCC2)c2ccccc12 -US09051333B2,1,Brc1ccc(OCc2ccccc2)cc1.C[C@@H]1CNCCN1C(=O)OCc1ccccc1>>C[C@@H]1CN(c2ccc(OCc3ccccc3)cc2)CCN1C(=O)OCc1ccccc1 -US20120035164A1,3,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1.COCCCNCc1ccc(B(O)O)s1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc(CNCCCOC)s4)cc23)CC1 -US06197728B1,7,COC(=O)C(C)Oc1ccc(Oc2cnc3cc(F)ccc3n2)cc1>>CC(CO)Oc1ccc(Oc2cnc3cc(F)ccc3n2)cc1 -US20020137736A1,7,CNCc1cc([N+](=O)[O-])ccc1OC>>CNCc1cc(N)ccc1OC -US06410566B1,2,Clc1ccc(CN2CCC(CNCC(c3ccccc3)c3ccccc3)CC2)cc1.O=C(O)CNC(=O)c1ccccc1>>O=C(NCC(=O)N(CC1CCN(Cc2ccc(Cl)cc2)CC1)CC(c1ccccc1)c1ccccc1)c1ccccc1 -US20130137865A1,1,Cn1ncc(I)c1CCc1ccc(C(F)(F)F)cc1.c1cn[nH]c1>>Cn1ncc(-n2cccn2)c1CCc1ccc(C(F)(F)F)cc1 -US04943574,3,O=C(Cl)c1ccc(F)c([N+](=O)[O-])c1.c1ccccc1>>O=C(c1ccccc1)c1ccc(F)c([N+](=O)[O-])c1 -US05519034,2,CCCCCCCCCC(=O)Cl.CN1CCc2cc(F)c(O)cc2C1C1(c2ccccc2Cl)CCC1>>CCCCCCCCCC(=O)Oc1cc2c(cc1F)CCN(C)C2C1(c2ccccc2Cl)CCC1 -US04966971,3,CN(C)C=O.COc1ccc2c(ccn2C)c1>>COc1ccc2c(c1)c(C=O)cn2C -US05132303,1,C=C1N(CCCC)C(=O)OC12CCNCC2.Clc1ccc(C(=CCCBr)c2ccc(Cl)cc2)cc1>>C=C1N(CCCC)C(=O)OC12CCN(CCC=C(c1ccc(Cl)cc1)c1ccc(Cl)cc1)CC2 -US20050096359A1,1,CC(c1cccc(-c2ccccc2CN)c1)N(C(=O)Cc1ccc(Cl)cc1)C1CCN(Cc2ccccc2)CC1.NC(=O)CCl>>CC(c1cccc(-c2ccccc2CNCC(N)=O)c1)N(C(=O)Cc1ccc(Cl)cc1)C1CCN(Cc2ccccc2)CC1 -US20030195209A1,1,Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C.NCCC1CCN(Cc2ccccc2)CC1>>Cc1nc(Cl)c([N+](=O)[O-])c(NCCC2CCN(Cc3ccccc3)CC2)c1C -US05246948,7,O=C1c2ccccc2C(=O)N1CCCSc1ccncc1>>O=C1c2ccccc2C(O)N1CCCSc1ccncc1 -US07132425B2,3,C=CC[Sn](CCCC)(CCCC)CCCC.Nc1cnc(Br)cn1>>C=CCc1cnc(N)cn1 -US08563565B2,10,COc1cc(C)c(Br)c(C)n1.O=C1CCC(=O)N1Br>>COc1cc(C)c(Br)c(CBr)n1 -US20150087646A1,2,COC(=O)c1ccc(-n2nc(-c3cc(CNC(=O)C4CC4)ccc3Cl)[nH]c2=O)cc1.Nc1cccc(C(F)(F)F)c1>>O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(-n2nc(-c3cc(CNC(=O)C4CC4)ccc3Cl)[nH]c2=O)cc1 -US04795751,1,CN1CCN(c2c(F)c(F)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1.NCc1ccccc1>>CN1CCN(c2c(F)c(NCc3ccccc3)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 -US08686022B2,1,C=O.COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)[C@H]5CCNC5)CC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)[C@H]5CCN(C)C5)CC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O -US06683097B2,1,Cc1ncc[nH]1.ClCc1cncc(-c2ccc(Cl)c(Cl)c2)c1>>Cc1nccn1Cc1cncc(-c2ccc(Cl)c(Cl)c2)c1 -US20090264399A1,6,CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](CO)C1>>N[C@@H]1CCC[C@H](CO)C1 -US20100029609A1,2,Cc1cc(S(=O)(=O)Nc2cccc(-c3ccc(C(=O)O)cc3)c2)c(C)cc1Cl.NCCO>>Cc1cc(S(=O)(=O)Nc2cccc(-c3ccc(C(=O)NCCO)cc3)c2)c(C)cc1Cl -US04001426,6,COc1ccc(-c2oc3ccccc3c2C(=O)c2cc(Cl)cc(Cl)c2)cc1>>O=C(c1cc(Cl)cc(Cl)c1)c1c(-c2ccc(O)cc2)oc2ccccc12 -US20140005213A1,6,CC(C)(C)OC(=O)N[C@]1(CO)CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)N[C@]1(CO)CCNC1 -US08138189B2,1,COC(=O)c1ccc(B(O)O)cc1F.Cc1cc(C(O)(C(C)c2ccc(O)cc2Cl)C(F)(F)F)cn(C)c1=O>>COC(=O)c1ccc(Oc2ccc(C(C)C(O)(c3cc(C)c(=O)n(C)c3)C(F)(F)F)c(Cl)c2)cc1F -US20060004049A1,2,NC12CC3CC(CC(C3)C1)C2.O=C(O)[C@H]1CCCN(c2ccccc2)C1>>O=C(NC12CC3CC(CC(C3)C1)C2)[C@H]1CCCN(c2ccccc2)C1 -US20040186177A1,7,CCC[C@@H](C)C[C@@H](CC(=O)OC(C)(C)C)C(=O)O>>CCC[C@@H](C)C[C@H](CO)CC(=O)OC(C)(C)C -US20040192685A1,6,O=C(c1ccccc1)N1CCc2cc(OCc3ccccc3)ccc2C1c1ccc(OCCN2CCCC2)cc1>>O=C(c1ccccc1)N1CCc2cc(O)ccc2C1c1ccc(OCCN2CCCC2)cc1 -US08828997B2,1,BrCCSc1ccccc1.C[C@@]1(C(F)(F)F)Cn2c(nc(N3CCOCC3)cc2=O)N1>>C[C@@]1(C(F)(F)F)Cn2c(nc(N3CCOCC3)cc2=O)N1CCSc1ccccc1 -US07998975B2,9,CC(C)(NC(=O)OCc1ccccc1)C(=O)O.N>>CC(C)(NC(=O)OCc1ccccc1)C(N)=O -US20150018331A1,1,C1COCCN1.CC(C)(C)OC(=O)N1CCN(c2ccc(C=O)cc2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(CN3CCOCC3)cc2)CC1 -US04537893,2,CC(=O)Cl.CCCN1CCC[C@H]2Cc3nc(N)sc3C[C@@H]21>>CCCN1CCC[C@H]2Cc3nc(NC(C)=O)sc3C[C@@H]21 -US07608618B2,6,COC(=O)c1ccc(NC(=O)Nc2cnc(C)cn2)c(OCc2cccnc2)c1>>Cc1cnc(NC(=O)Nc2ccc(C(=O)O)cc2OCc2cccnc2)cn1 -US06613942B1,1,BrCCBr.Cc1cc(C=O)cc(C)c1O>>Cc1cc(C=O)cc(C)c1OCCBr -US20090137804A1,2,CNc1cc(Nc2cccc(Cl)c2)ncn1.Cc1cccc(C)c1N=C=O>>Cc1cccc(C)c1NC(=O)N(C)c1cc(Nc2cccc(Cl)c2)ncn1 -US20140107085A1,1,COC(=O)c1cccc(Br)c1.Nc1ccccc1>>COC(=O)c1cccc(Nc2ccccc2)c1 -US08748434B2,6,COC(=O)c1cc(C(F)(F)F)cc(S(=O)(=O)N2CCOCC2)c1>>O=C(O)c1cc(C(F)(F)F)cc(S(=O)(=O)N2CCOCC2)c1 -US20070155805A1,6,CCCCC(CCOc1ccc(CCC(=O)OC)cc1OC)c1sc2cc(C(F)(F)F)ccc2c1C>>CCCCC(CCOc1ccc(CCC(=O)O)cc1OC)c1sc2cc(C(F)(F)F)ccc2c1C -US05620968,6,CCOC(=O)Cc1csc(-c2ccccc2O)n1>>O=C(O)Cc1csc(-c2ccccc2O)n1 -US06699858B2,7,O=c1c2ccccc2ccc2cc(F)ccc12>>Fc1ccc2c(c1)C=Cc1ccccc1C2 -US20040106653A1,6,CCOC(=O)c1cc(S(=O)(=O)c2ccc(CCN(C[C@H](OC3CCCCO3)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)ccc1NC>>CCOC(=O)c1cc(S(=O)(=O)c2ccc(CCN(C[C@H](O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)ccc1NC -US08524917B2,7,COc1ccc(C#CC(C)C)c([N+](=O)[O-])c1>>COc1ccc(C#CC(C)C)c(N)c1 -US20060074237A1,2,Cc1ccc(F)cc1S(=O)(=O)Cl.Nc1cccc(COCc2ccc(F)cc2)n1>>Cc1ccc(F)cc1S(=O)(=O)Nc1cccc(COCc2ccc(F)cc2)n1 -US20050250836A1,3,COc1cccc(Cl)c1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Cn1cccc1C=O>>COc1cccc(Cl)c1C=Cc1cccn1C -US20080200523A1,1,C1COCCN1.CC(=O)Oc1ccc(CCl)cc1>>CC(=O)Oc1ccc(CN2CCOCC2)cc1 -US06265434B1,7,CC(C)(C)OC(=O)N1CCC(C=O)CC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1 -US20090264336A1,1,Cn1ccc(NC(=O)c2cc(O)cc(O[C@H]3CCOC3)c2)n1.O=C(c1cnc(Cl)c(Cl)c1)N1CCOCC1>>Cn1ccc(NC(=O)c2cc(Oc3ncc(C(=O)N4CCOCC4)cc3Cl)cc(O[C@H]3CCOC3)c2)n1 -US06861418B2,3,COc1cccc(-c2cccc3c2CC(=O)N3)c1.Cc1cc(C)c(C=O)[nH]1>>COc1cccc(-c2cccc3c2C(=Cc2[nH]c(C)cc2C)C(=O)N3)c1 -US07709500B2,2,CNS(=O)(=O)c1ccc2c(C(=O)O)c[nH]c(=O)c2c1.NC[C@@H](O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1>>CNS(=O)(=O)c1ccc2c(C(=O)NC[C@@H](O)CN3CCC(Oc4ccc(Cl)c(Cl)c4)CC3)c[nH]c(=O)c2c1 -US20150056164A1,3,CC1(C)OB(c2ccc3cc(NS(C)(=O)=O)ccc3c2)OC1(C)C.COc1c(Br)cc(NC(C)=O)cc1C(C)(C)C>>COc1c(-c2ccc3cc(NS(C)(=O)=O)ccc3c2)cc(NC(C)=O)cc1C(C)(C)C -US04888337,1,CCCCCCCCCCCCCC1CCC(OCCN(C)C)O1.CI>>CCCCCCCCCCCCCC1CCC(OCC[N+](C)(C)C)O1 -US04797399,2,NN1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1.O=C(Cl)c1ccc(F)cc1>>O=C(NN1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1)c1ccc(F)cc1 -US20100323994A1,2,CCNc1cc(N[C@@H]2CC[C@@H](N)CC2)nn2c(C(=O)Nc3ccncc3F)cnc12.O=C=Nc1ccc(F)cc1>>CCNc1cc(N[C@@H]2CC[C@@H](NC(=O)Nc3ccc(F)cc3)CC2)nn2c(C(=O)Nc3ccncc3F)cnc12 -US03950380,1,CC=CCBr.Nc1cc(C(=O)O)cc(S(N)(=O)=O)c1-c1ccccc1>>CC=CCNc1cc(C(=O)O)cc(S(N)(=O)=O)c1-c1ccccc1 -US20050137171A1,6,c1ccc(COc2ccc3[nH]nc(-c4cc5cc(OCCN6CCCCC6)ccc5[nH]4)c3c2)cc1>>Oc1ccc2[nH]nc(-c3cc4cc(OCCN5CCCCC5)ccc4[nH]3)c2c1 -USRE042890E1,1,N#CCCNc1nonc1-c1nc2ccccc2[nH]1.O=C(CBr)c1ccc(Cl)cc1>>N#CCCNc1nonc1-c1nc2ccccc2n1CC(=O)c1ccc(Cl)cc1 -US20140121200A1,1,Clc1cc2nccnc2c(Cl)n1.NCCCN>>NCCCNc1nc(Cl)cc2nccnc12 -US04910211,6,COC(=O)c1ccc(-c2nc3c(OC)cccc3s2)cc1>>COC(=O)c1ccc(-c2nc3c(O)cccc3s2)cc1 -US20040242659A1,1,CS(=O)(=O)Cc1nccn1CCCCc1ccc(O)cc1.Fc1ccc(/C=C/c2nc(CCl)co2)cc1>>CS(=O)(=O)Cc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3ccc(F)cc3)n2)cc1 -US20140235614A1,6,CC(=O)Nc1cc(Oc2cc3cc[nH]c3cc2OC(C)C)ccn1>>CC(C)Oc1cc2[nH]ccc2cc1Oc1ccnc(N)c1 -US07326716B2,3,CCCCCC(=O)CP(=O)(OC)OC.COC(=O)CCCCCCN1C(=O)CCC[C@@H]1C=O>>CCCCCC(=O)/C=C/[C@H]1CCCC(=O)N1CCCCCCC(=O)OC -US20140349993A1,2,CC1(C)OCC(COc2cccc(C(=O)O)n2)O1.Cc1c(-c2ccccc2C(F)(F)F)nn2c(N)cnc2c1C>>Cc1c(-c2ccccc2C(F)(F)F)nn2c(NC(=O)c3cccc(OCC4COC(C)(C)O4)n3)cnc2c1C -US20040030131A1,3,C=O.CNC.O=C1CCC2CCC1C2>>CN(C)CC1CC2CCC(C2)C1=O -US20140249104A1,2,CC1(C)OB(c2ccc(F)c([C@]3(CF)C[C@@H](C(F)(F)F)OC(N)=N3)c2)OC1(C)C.O=C(OC(=O)c1ccccc1)c1ccccc1>>CC1(C)OB(c2ccc(F)c([C@]3(CF)C[C@@H](C(F)(F)F)OC(NC(=O)c4ccccc4)=N3)c2)OC1(C)C -US07825238B2,6,CCCCCCCCCCCCCCCCC(OC(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C)C(=O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@@H]1F>>CCCCCCCCCCCCCCCCC(OC(=O)[C@@H](N)C(C)C)C(=O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@@H]1F -US07935699B2,6,CC(C)(C)[Si](C)(C)OCCn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(C#N)c2)n1>>CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2ccn(CCO)n2)cc1C#N -US07683078B2,2,CC(C)(CN)CO.O=C(NCc1ccc(S(=O)(=O)Cl)s1)c1ccc(Cl)cc1>>CC(C)(CO)CNS(=O)(=O)c1ccc(CNC(=O)c2ccc(Cl)cc2)s1 -US20070244153A1,6,CC(C)[C@@H](CNC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)NC(=O)OC(C)(C)C>>CC(C)[C@H](N)CNC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C -US09056883B2,1,Brc1ccc(-c2nc3ccccc3nc2-c2ccccc2)cc1.c1ccc(-c2ccc3[nH]c4ccc(-c5ccccc5)cc4c3c2)cc1>>c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc(-c3nc4ccccc4nc3-c3ccccc3)cc2)cc1 -US06413974B1,1,Clc1nc(Cl)c2ncn(C3CCCC3)c2n1.NCCCCN>>NCCCCNc1nc(Cl)nc2c1ncn2C1CCCC1 -US06352993B1,1,Cc1nc(Nc2ccc(F)cc2)nc(N2CCc3cc(O)ccc3C2C)c1C.O=C(O)CN1CCCCC1>>Cc1nc(Nc2ccc(F)cc2)nc(N2CCc3cc(OC(=O)CN4CCCCC4)ccc3C2C)c1C -US08436023B2,1,Cn1nc(NCC(=O)NC2CNC2)c2cc(C(F)C(F)(F)F)ccc21.O=C1CCC(O)(c2cncs2)CC1>>Cn1nc(NCC(=O)NC2CN(C3CCC(O)(c4cncs4)CC3)C2)c2cc(C(F)C(F)(F)F)ccc21 -US06005008,2,Nc1ccc(C(F)(F)F)cc1O.O=C=Nc1ccccc1Br>>O=C(Nc1ccc(C(F)(F)F)cc1O)Nc1ccccc1Br -US20140357640A1,2,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.O=S(=O)(Cl)c1cc(Cl)ccc1F>>CC1(C)OB(c2ccc(NS(=O)(=O)c3cc(Cl)ccc3F)cc2)OC1(C)C -US20110319378A1,3,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)C(C)=O)C1=O.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)C(C)=COC)C1=O -US20130172384A1,3,COc1ccc(B(O)O)c(Cl)c1.O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)n[nH]c2=O)C1>>COc1ccc(-c2ccc(-c3n[nH]c(=O)n3C[C@@H]3CCN(C(=O)C4CC4)C3)cc2)c(Cl)c1 -US20110190351A1,6,COc1ccc(C(=O)NCCNS(=O)(=O)c2ccccc2)c2nc(-c3cccs3)[nH]c12>>O=C(NCCNS(=O)(=O)c1ccccc1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 -US20080261945A1,1,CC(C)[C@H](N)CO.O=Cc1ccccc1>>CC(C)[C@@H](CO)N=Cc1ccccc1 -US07585886B2,8,O=C(CCCCC(=O)N1C[C@H](CO)[C@@H](c2cccc(C(F)(F)F)c2)C1)OCc1ccccc1>>O=C[C@H]1CN(C(=O)CCCCC(=O)OCc2ccccc2)C[C@@H]1c1cccc(C(F)(F)F)c1 -US06608059B1,6,CCOC(=O)c1cc2cc(OCc3c(Cl)cccc3Cl)ccc2n1CCCC#N>>N#CCCCn1c(C(=O)O)cc2cc(OCc3c(Cl)cccc3Cl)ccc21 -US20090247559A1,2,NCc1ccccc1Cl.O=C(O)C1CCN(Cc2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)C1>>O=C(NCc1ccccc1Cl)C1CCN(Cc2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)C1 -US05643938,6,COC(=O)C[C@H]1CCCCN1C(=O)C=Cc1c(-c2ccccc2)nn2ccccc12>>O=C(O)C[C@H]1CCCCN1C(=O)C=Cc1c(-c2ccccc2)nn2ccccc12 -US06316467B1,1,NC(=O)CCC(=O)c1ccccc1.NNC(N)=S>>NC(=O)CCC(=NNC(N)=S)c1ccccc1 -US20090326059A1,1,Cc1cc(O)cc(C)c1[N+](=O)[O-].Fc1ccc(CCl)cc1>>Cc1cc(OCc2ccc(F)cc2)cc(C)c1[N+](=O)[O-] -US09139581B2,1,Nc1ccc2cn[nH]c2c1.Nc1nc(Cl)nc2[nH]ccc12>>Nc1nc(Nc2ccc3cn[nH]c3c2)nc2[nH]ccc12 -US20080161366A1,1,CCN.O=S1(=O)N(CCCBr)c2ccccc2N1c1ccc(Cl)cc1>>CCNCCCN1c2ccccc2N(c2ccc(Cl)cc2)S1(=O)=O -US04578381,7,NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O>>NC(CC1CC(=O)Nc2ccccc21)C(=O)O -US20150225342A1,3,CON(C)C(=O)c1ccc2[nH]nnc2c1.C[Mg+]>>CC(=O)c1ccc2[nH]nnc2c1 -US20090029947A1,7,CCCCCCCCc1ccc(C2CC(N)(C(=O)O)CO2)cc1>>CCCCCCCCc1ccc(C2CC(N)(CO)CO2)cc1 -US20140288123A1,1,CC(C)CC(O)c1ccc(Br)cc1.Oc1ccccc1>>CC(C)CC(Oc1ccccc1)c1ccc(Br)cc1 -US20120214803A1,3,Fc1ccc([Mg]Br)cc1.O=Cc1ccc2cccnc2c1[N+](=O)[O-]>>O=[N+]([O-])c1c(C(O)c2ccc(F)cc2)ccc2cccnc12 -US20130102576A1,2,CS(=O)(=O)Cl.Nc1ccc2c(c1)C(=O)N(CC(=O)OCc1ccccc1)C2=O>>CS(=O)(=O)Nc1ccc2c(c1)C(=O)N(CC(=O)OCc1ccccc1)C2=O -US20120232279A1,8,CCCCCCCCO>>CCCCCCCC=O -US20080058311A1,2,CC(C)(C)N.O=C(O)CCC(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1>>CC(C)(C)NC(=O)CCC(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1 -US07067534B1,2,CC(C)(C)N=C=S.CC(C)C(=O)Nc1cccc(C2CCN(CCCN)CC2)c1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCNC(=S)NC(C)(C)C)CC2)c1 -US08114873B2,3,Cc1ccc(C)c(B(O)O)c1.O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1cccc(Br)c1>>Cc1ccc(C)c(-c2cccc(C(=O)Nc3ccc(OCCN4CCOCC4)c4ccccc34)c2)c1 -US04588591,7,O=C1CCC2(CCOC2)CC1>>OC1CCC2(CCOC2)CC1 -US20120282629A1,1,NNc1ccc(F)cc1.O=Cc1cccc(O)c1O>>Oc1cccc(C=NNc2ccc(F)cc2)c1O -US06384072B1,1,CCOC(=O)CBr.O=C(OCC1(O)CCCc2c(O)cccc2C1O)N(c1ccccc1)c1ccccc1>>CCOC(=O)COc1cccc2c1CCCC(O)(COC(=O)N(c1ccccc1)c1ccccc1)C2O -US08314240B2,6,CCOC(=O)c1cnc(COc2cc3c(cc2NC(=O)OC(C)(C)C)CCC3)cn1>>CCOC(=O)c1cnc(COc2cc3c(cc2N)CCC3)cn1 -US20100216764A1,7,CCOC(=O)c1cnn(-c2cccc(-c3ccccc3OCc3ccc(C4=CCN(C(=O)OC(C)(C)C)CC4)cc3)n2)c1C(F)(F)C(F)(F)F>>CCOC(=O)c1cnn(-c2cccc(-c3ccccc3OCc3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc3)n2)c1C(F)(F)C(F)(F)F -US08183381B2,1,CC(C)(C)OC(=O)N1CCC(n2cnc(COS(C)(=O)=O)n2)CC1.CS(=O)(=O)c1ccc(O)c(F)c1>>CC(C)(C)OC(=O)N1CCC(n2cnc(COc3ccc(S(C)(=O)=O)cc3F)n2)CC1 -US06051712,2,CC(C)(C)OC(=O)N1CCC(c2ccc(CCO)cc2)C(OCc2ccc3ccccc3c2)C1.O=C=Nc1ccccc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(CCOC(=O)Nc3ccccc3)cc2)C(OCc2ccc3ccccc3c2)C1 -US20130102617A1,6,COC(=O)c1cnc(CCOC2CCCCO2)cn1>>O=C(O)c1cnc(CCOC2CCCCO2)cn1 -US20100035871A1,2,CC(=O)OC(C)=O.COc1cccc2c1NC(CN)CO2>>COc1cccc2c1NC(CNC(C)=O)CO2 -US08445674B2,7,COC(=O)[C@@H](CCC(=O)N1CCC2(CC2)[C@H](O)C1)N1CCN(C(=O)Nc2ccc(C(F)(F)F)c(Cl)c2)[C@@H](C)C1=O>>C[C@H]1C(=O)N([C@@H](CO)CCC(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)Nc1ccc(C(F)(F)F)c(Cl)c1 -US05364944,6,COc1ccc(-c2ccc(C(C)=O)cc2[N+](=O)[O-])cc1>>CC(=O)c1ccc(-c2ccc(O)cc2)c([N+](=O)[O-])c1 -US08952010B2,1,CC(C)(C)OC(=O)N[C@H]1CNC(=O)C1.COCN1C(=O)COc2ccc(Br)cc21>>COCN1C(=O)COc2ccc(N3C[C@H](NC(=O)OC(C)(C)C)CC3=O)cc21 -US20130053381A1,1,CCOC(=O)CCC(=O)Cl.CS(=O)(=O)Nn1c(=O)[nH]c2cc(C(F)(F)F)c(-n3ccnc3)cc2c1=O>>CCOC(=O)CCC(=O)N(n1c(=O)[nH]c2cc(C(F)(F)F)c(-n3ccnc3)cc2c1=O)S(C)(=O)=O -US08063073B2,2,CS(=O)(=O)c1ccc(CN)cc1.Cc1ccc(C(=O)O)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1ccc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1 -US20150166527A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.COC(=O)c1c(I)ccc(C)c1F>>COC(=O)c1c(-c2ccccn2)ccc(C)c1F -US06451819B2,6,CC(C)(C)OC(=O)N1CC[C@@H](Sc2ccc(O)cc2)C1>>Oc1ccc(S[C@@H]2CCNC2)cc1 -US20140163012A1,1,CC(C)(C)OC(=O)N1CCc2c(oc3cc(Br)ccc23)C1.O=c1cc(OCc2ccc(F)cn2)cc[nH]1>>CC(C)(C)OC(=O)N1CCc2c(oc3cc(-n4ccc(OCc5ccc(F)cn5)cc4=O)ccc23)C1 -US20070111998A1,6,OC(CNC1CCN(Cc2ccccc2)CC1)COc1cccc2[nH]c3ccccc3c12>>OC(CNC1CCNCC1)COc1cccc2[nH]c3ccccc3c12 -US20140155385A1,2,CC#CC(=O)O.Nc1nccn2c([C@@H]3CCCCN3)nc(-c3ccc(C(=O)Nc4ccon4)cc3)c12>>CC#CC(=O)N1CCCC[C@H]1c1nc(-c2ccc(C(=O)Nc3ccon3)cc2)c2c(N)nccn12 -US20050014812A1,1,CCOC(=O)CCCOc1ccc(NC(C)=O)c(N)c1.ClCc1ccc(Cl)cc1Cl>>CCOC(=O)CCCOc1ccc(NC(C)=O)c(NCc2ccc(Cl)cc2Cl)c1 -US20100004271A1,2,COC(=O)C(F)Cc1cc(Br)c(Oc2ccc(N)c([N+](=O)[O-])c2)c(Br)c1.O=C(Cl)CCl>>COC(=O)C(F)Cc1cc(Br)c(Oc2ccc(NC(=O)CCl)c([N+](=O)[O-])c2)c(Br)c1 -US09051265B2,1,COC(=O)[C@@H](C)O.Cc1cc(O)cc(Cl)c1>>COC(=O)[C@H](C)Oc1cc(C)cc(Cl)c1 -US20120214858A1,1,CCCCCCCBr.O=Cc1ccc(O)cc1>>CCCCCCCOc1ccc(C=O)cc1 -US04473395,7,CCOC(=O)c1cc(-c2ccc([N+](=O)[O-])cc2)cnc1C>>CCOC(=O)c1cc(-c2ccc(N)cc2)cnc1C -US05677346,3,C#CCO.C=O.CCNCc1ccc(OC)cc1>>CCN(CC#CCO)Cc1ccc(OC)cc1 -US20150158818A1,6,CCOC(=O)c1cnn(C)c1C(=O)OCC>>CCOC(=O)c1cnn(C)c1C(=O)O -US20060100204A1,4,C#Cc1ccc(Cl)nc1.Cc1ccc(C(=O)O)cc1N=[N+]=[N-]>>Cc1ccc(C(=O)O)cc1-n1cc(-c2ccc(Cl)nc2)nn1 -US20070249670A1,2,COC(=O)[C@@H](N)C1CCCCC1.O=C(Nc1cc(-c2cccnc2)sc1C(=O)O)Nc1c(Cl)cccc1Cl>>COC(=O)[C@@H](NC(=O)c1sc(-c2cccnc2)cc1NC(=O)Nc1c(Cl)cccc1Cl)C1CCCCC1 -US04499102,1,C[C@H](S)C(=O)N1CCC[C@H]1C(=O)O.O=C(O)C(Br)CCc1ccccc1>>C[C@H](SC(CCc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)O -US07423030B2,6,COc1ccc(-c2nnc(NC3CCN(Cc4ccccc4)CC3)c3cc(OC)ccc23)cc1>>COc1ccc(-c2nnc(NC3CCNCC3)c3cc(OC)ccc23)cc1 -US05734051,7,CCCCn1c(=O)c2[nH]c([N+](=O)[O-])nc2n(CCCC)c1=O>>CCCCn1c(=O)c2[nH]c(N)nc2n(CCCC)c1=O -US20140356322A1,2,CC(=O)O[C@@H](C)C(=O)O.O=C(NCc1ccc(-c2cnco2)cc1)[C@@H]1C[C@@H](O)CN1>>CC(=O)O[C@@H](C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2cnco2)cc1 -US20080132540A1,1,CC(C)(C)OC(=O)N1CCc2ccc(N)cc21.O=C1CCN(Cc2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCc2ccc(NC3CCN(Cc4ccccc4)CC3)cc21 -US06046355,7,O=C(C=Cc1cccc(O)c1)c1ccccc1>>O=C(CCc1cccc(O)c1)c1ccccc1 -US06057087,4,CC(=O)CCC(C)=O.NCc1ccccc1>>Cc1ccc(C)n1Cc1ccccc1 -US20100048611A1,1,COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(NCCO[Si](C)(C)C(C)(C)C)cc2)CC3)cc1.N#CBr>>COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(N(C#N)CCO[Si](C)(C)C(C)(C)C)cc2)CC3)cc1 -US06143764,2,CC(=O)Oc1ccc(C(=O)O)cc1.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)c4ccc(OC(C)=O)cc4)cc3)c2cc1OC -US20100280001A1,2,CCCCc1nc2c(N)nc3ccccc3c2n1CCCNCc1ccc(CC(=O)OC)cc1.CN(C)CC(=O)Cl>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)C -US07329775B2,6,CC(C)(C)OC(=O)NC(COCc1ccccc1)C(=O)N1CCOCC1>>CC(C)(C)OC(=O)NC(CO)C(=O)N1CCOCC1 -US20080045530A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CN(Cc2cccc3ccccc23)C[C@H]1C(=O)O>>CC(C)(C)OC(=O)N[C@@H]1CN(Cc2cccc3ccccc23)C[C@H]1C(=O)O -US20120252801A1,1,CC(C)c1ccc(NC(=O)CC2NCC(C)(C)OC2=O)cc1.CCC=O>>CCCN1CC(C)(C)OC(=O)C1CC(=O)Nc1ccc(C(C)C)cc1 -US04093626,1,O=C1CC2OC(CBr)CN12.[S-]c1ccccc1>>O=C1CC2OC(CSc3ccccc3)CN12 -US20100160324A1,1,CCOC(=O)c1n[nH]cc1[N+](=O)[O-].COc1ccc(CCl)cc1>>CCOC(=O)c1nn(Cc2ccc(OC)cc2)cc1[N+](=O)[O-] -US20140275087A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1cnc(S(=O)(=O)N2C[C@H](NCCO[Si](C)(C)C(C)(C)C)[C@@H](c3ccccc3)C2)c1>>Cn1cnc(S(=O)(=O)N2C[C@H](c3ccccc3)[C@@H](N(CCO[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C)C2)c1 -US07179912B2,4,Nc1ccc(N2CCOCC2)cc1N.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ccc(N3CCOCC3)cc2[nH]1 -US04831152,2,Nc1cc(Cl)c([N+](=O)[O-])cc1O.O=C(Cl)c1ccccc1>>Nc1cc(Cl)c([N+](=O)[O-])cc1OC(=O)c1ccccc1 -US20110009454A1,2,NCc1cccc(Oc2ccc(F)cc2)c1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1cccc(Oc2ccc(F)cc2)c1 -US05847149,3,Brc1nnc(-c2ccccc2)s1.CCCCCCCCCCOc1ccc(B(O)O)c(F)n1>>CCCCCCCCCCOc1ccc(-c2nnc(-c3ccccc3)s2)c(F)n1 -US20100099663A1,1,FC(F)(F)Oc1ccc(Br)cc1.Oc1ccccc1>>FC(F)(F)Oc1ccc(Oc2ccccc2)cc1 -US07625908B2,1,C=CCN(C)C[C@@H](C)O.Oc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl>>C=CCN(C)C[C@@H](C)Oc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12 -US20090209578A1,6,CC(=O)C[C@H](NC(=O)OC(C)(C)C)c1ccccc1>>CC(=O)C[C@H](N)c1ccccc1 -US07491819B1,2,CC(C)(C)[Si](C)(C)OC[C@@H]1CCC(=O)N1c1cc(F)ccc1CN.CC1(C)OCCn2c1nc(C(=O)O)c(OCc1ccccc1)c2=O>>CC1(C)OCCn2c1nc(C(=O)NCc1ccc(F)cc1N1C(=O)CC[C@@H]1CO[Si](C)(C)C(C)(C)C)c(OCc1ccccc1)c2=O -US20150141409A1,1,BrCCC1OCCO1.O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1>>O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)OCCC1OCCO1)c1ccc(Cl)cc1 -US20110218177A1,1,COc1cc(O)ccc1C=O.OCCBr>>COc1cc(OCCO)ccc1C=O -US20020042431A1,3,O=C1CCC=C1Br.OB(O)c1ccc(F)cc1>>O=C1CCC=C1c1ccc(F)cc1 -US08569319B2,2,CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Cl.Cn1cc(-c2cnccc2Oc2cc(F)c(N)cc2Cl)cn1>>CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1cc(Cl)c(Oc2ccncc2-c2cnn(C)c2)cc1F -US07122545B2,2,COc1ccc(N2CCOCC2)c2sc(C(=O)O)nc12.NCC(=O)c1cccs1>>COc1ccc(N2CCOCC2)c2sc(C(=O)NCC(=O)c3cccs3)nc12 -US20040023974A1,6,COc1ccc(CN2C(=O)CN(Cc3cccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OCc4ccccc4)c3)S2(=O)=O)cc1>>COc1ccc(CN2C(=O)CN(Cc3cccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)c3)S2(=O)=O)cc1 -US20140357641A1,1,Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)NCCC3)cc1.O=CCCCCOCc1ccccc1>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCCOCc2ccccc2)CCC3)cc1 -US20080085886A1,6,CCOC(=O)c1oc2c(Cl)cncc2c1Nc1ccc(I)cc1F>>O=C(O)c1oc2c(Cl)cncc2c1Nc1ccc(I)cc1F -US20070129354A1,2,CCO.O=C(O)c1ccc(Br)c(O)c1>>CCOC(=O)c1ccc(Br)c(O)c1 -US08134000B2,2,Cc1ncc(-c2ncnc(Nc3ccc(C(=O)O)cc3)n2)n1C(C)C.Nc1ccccc1N>>Cc1ncc(-c2ncnc(Nc3ccc(C(=O)Nc4ccccc4N)cc3)n2)n1C(C)C -US06444672B1,2,CS(=O)(=O)Cl.O=CN1CCNCC1>>CS(=O)(=O)N1CCN(C=O)CC1 -US20150011562A1,7,Cc1ccc(F)cc1N1CCN(c2cc(Cl)c(C(=O)NCCCN3CCCC3=O)cc2[N+](=O)[O-])CC1>>Cc1ccc(F)cc1N1CCN(c2cc(Cl)c(C(=O)NCCCN3CCCC3=O)cc2N)CC1 -US20020147334A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Br)cn1>>CC(C)(C)OC(=O)Nc1ccc(Br)cn1 -US20140243310A1,7,C[C@@H](COc1cc(O)c([N+](=O)[O-])cn1)NC(=O)OC(C)(C)C>>C[C@@H](COc1cc(O)c(N)cn1)NC(=O)OC(C)(C)C -US04611002,2,CC(=O)SCC(C)C(=O)O.O=C(O)CO>>CC(=O)SCC(C)C(=O)OC(=O)CO -US08901141B2,8,Cc1cc(Cl)cc(Cl)c1N1CCn2c1nc1c(Cl)ccc(CO)c12>>Cc1cc(Cl)cc(Cl)c1N1CCn2c1nc1c(Cl)ccc(C=O)c12 -US08148380B2,1,NCCO.O=C(NCc1ccc(Cl)c(Cl)c1)Nc1nc(CI)cs1>>O=C(NCc1ccc(Cl)c(Cl)c1)Nc1nc(CNCCO)cs1 -US20080032998A1,2,CC1CC(c2cncnc2)=CCN1.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1CC(c2cncnc2)=CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US05968938,6,CCc1cccc(N2CCN(C(=O)OC(C)(C)C)CC2)c1>>CCc1cccc(N2CCNCC2)c1 -US07968587B2,6,CC(C)(C)OC(=O)N[C@@H]1Cc2c(n(Cc3ccsn3)c3ccc(C#N)cc23)C1>>N#Cc1ccc2c(c1)c1c(n2Cc2ccsn2)C[C@H](N)C1 -US20110301142A1,1,CCOC(=O)Cc1ccccc1O.Cc1noc(-c2ccc(CCl)cc2)c1NC(=O)O[C@H](C)c1ccccc1Cl>>CCOC(=O)Cc1ccccc1OCc1ccc(-c2onc(C)c2NC(=O)O[C@H](C)c2ccccc2Cl)cc1 -US06150373,1,CCI.CS(=O)(=O)c1ncc2c(n1)NC(=O)N(c1c(Cl)cccc1Cl)C2>>CCN1C(=O)N(c2c(Cl)cccc2Cl)Cc2cnc(S(C)(=O)=O)nc21 -US07638517B2,2,CN.O=C(O)CC(c1ccccc1)c1c[nH]c2cccnc12>>CNC(=O)CC(c1ccccc1)c1c[nH]c2cccnc12 -US20100099695A1,2,CS(=O)(=O)Cl.OCc1cc(Br)ccc1Cl>>CS(=O)(=O)OCc1cc(Br)ccc1Cl -US20130079320A1,2,CC(C(=O)O)c1ccc(F)c(C#N)c1.CC1CCN(c2nc(C(F)(F)F)ccc2CN)CC1>>CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(F)c(C#N)c2)CC1 -US20100311748A1,1,CCOC(=O)c1ccc(O)cc1.ClCc1ccccn1>>CCOC(=O)c1ccc(OCc2ccccn2)cc1 -US07999006B2,6,CC(C)(C)OC(=O)NC1CCCCC1C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1>>NC1CCCCC1C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US07999006B2,6,CC(C)(C)OC(=O)NC1CCCCC1C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1>>NC1CCCCC1C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US09120749B2,3,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)CC1.CC1(C)OB(c2cc(F)c(O)c(Cl)c2)OC1(C)C>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)CC1 -US06596734B1,6,COc1c(Br)cc(CC2NCCc3cc(OCc4ccccc4)c(NS(=O)(=O)c4ccc(C)cc4)cc32)cc1Br>>COc1c(Br)cc(CC2NCCc3cc(O)c(NS(=O)(=O)c4ccc(C)cc4)cc32)cc1Br -US04652297,6,CCOC(=O)CN(CP(=S)(N(C)C)N(C)C)C(=O)C(F)(F)F>>CCOC(=O)CNCP(=S)(N(C)C)N(C)C -US20110201603A1,7,CCc1cc(C(n2cc(C(F)(F)F)cn2)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc([N+](=O)[O-])c1>>CCc1cc(C(n2cc(C(F)(F)F)cn2)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(N)c1 -US06518257B1,3,CC(=O)NCc1cccc(Br)c1.CC(C)C(O)(c1ccc(B(O)O)cc1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC(=O)NCc1cccc(-c2ccc(C(O)(c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)C(C)C)cc2)c1 -US20090124602A1,2,Nc1ncc(Br)cc1C(=O)c1cccc(N2CCCNCC2)n1.O=C(O)CC(F)(F)F>>Nc1ncc(Br)cc1C(=O)c1cccc(N2CCCN(C(=O)CC(F)(F)F)CC2)n1 -US20100036118A1,2,CCNCC.COc1ccccc1-c1n[nH]c2ncc(-c3ccc(N)c(C(=O)O)c3)cc12>>CCN(CC)C(=O)c1cc(-c2cnc3[nH]nc(-c4ccccc4OC)c3c2)ccc1N -US20120129840A1,1,C1COCCN1.CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1>>CCCC(C(=O)OC)c1c(C)nc(N2CCOCC2)nc1-c1ccc(C)cc1 -US08846845B2,7,COC(=O)CCCCCOc1ccc([N+](=O)[O-])cc1>>COC(=O)CCCCCOc1ccc(N)cc1 -US20070149563A1,3,O=C(N[C@H]1CN2CCC1CC2)c1ccc(Br)s1.OB(O)c1ccncc1>>O=C(N[C@H]1CN2CCC1CC2)c1ccc(-c2ccncc2)s1 -US20050059669A1,1,Brc1ncccn1.COC(=O)c1cc(N2CCC(N)CC2)ccc1F>>COC(=O)c1cc(N2CCC(Nc3ncccn3)CC2)ccc1F -US20100324020A1,8,CC(C)(C)OC(=O)N1CC2C(CO)C2C1>>CC(C)(C)OC(=O)N1CC2C(C=O)C2C1 -US20110086853A1,6,CCOC(=O)[C@H]1CCCN(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)C1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CCC[C@H](C(=O)O)C3)ccc2n1CC1CCOCC1 -US08288367B2,6,COC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)C[C@@H](CCC(=O)Nc3ncc(C)s3)[C@@H]12>>Cc1cnc(NC(=O)CC[C@@H]2CC(=O)[C@@]3(C)CC[C@@H]4c5ccc(C(=O)O)cc5CC[C@H]4[C@H]23)s1 -US07122545B2,2,COc1ccc(N2CCOCC2)c2sc(-c3nc4c([nH]3)CCNCC4)nc12.O=C(Cl)c1ccc(F)cc1>>COc1ccc(N2CCOCC2)c2sc(-c3nc4c([nH]3)CCN(C(=O)c3ccc(F)cc3)CC4)nc12 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@@H](O)c3ccccc3)CC2)c1.Oc1cccc2ccccc12>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](Oc3cccc4ccccc34)c3ccccc3)CC2)c1 -US20050131015A1,9,N.O=C(O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21>>NC(=O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21 -US08969345B2,7,O=[N+]([O-])c1ncccc1OC(F)F>>Nc1ncccc1OC(F)F -US04698345,7,C=CCc1c(O)ccc2[nH]c(C(=O)OCC)cc12>>CCCc1c(O)ccc2[nH]c(C(=O)OCC)cc12 -US20040229858A1,6,COC(=O)c1ccc(OCC2CCCN2C(=O)OC(C)(C)C)c(C)c1>>COC(=O)c1ccc(OCC2CCCN2)c(C)c1 -US06057350,9,CCOC1(C#N)C=CC(C2(C(=O)OC)CCCCC2=O)=CC1>>CCOC1(C#N)C=CC(C2CCCCC2=O)=CC1 -US20060205774A1,2,CC(C)N1CCC(Oc2ccc(C3CCNCC3)cc2)CC1.O=C(O)c1ccc(F)cc1>>CC(C)N1CCC(Oc2ccc(C3CCN(C(=O)c4ccc(F)cc4)CC3)cc2)CC1 -US20140057902A1,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.O=C1C=C2c3cccc(I)c3CCN2C(=O)CN1>>C=C(OCC)c1cccc2c1CCN1C(=O)CNC(=O)C=C21 -US09018214B2,9,COC[C@H]1CN(C(=O)OC(C)(C)C)[C@H](C)CN1CC(=O)N1CC(C)(C)c2cc(Br)c(CN3CCCC3=O)cc21>>COC[C@H]1CN(C(=O)OC(C)(C)C)[C@H](C)CN1CC(=O)N1CC(C)(C)c2ccc(CN3CCCC3=O)cc21 -US06521649B1,2,CC(C)O.Cc1nnsc1C(=O)O>>Cc1nnsc1C(=O)OC(C)C -US20150183802A1,3,C=C(C)C(=O)OC.COc1cc(Br)ccc1F>>COC(=O)C(C)=Cc1ccc(F)c(OC)c1 -US06927228B2,2,Nc1cccc(-c2ccc(C=C3SC(=O)NC3=O)cc2)c1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1cccc(-c2ccc(C=C3SC(=O)NC3=O)cc2)c1 -US20080318923A1,1,BrCCOCc1ccccc1.C[C@H](NC(=O)OCc1ccccc1)C(=O)N(C)C>>C[C@@H](C(=O)N(C)C)N(CCOCc1ccccc1)C(=O)OCc1ccccc1 -US08742110B2,7,O=C(O)c1cc(Cl)c(I)c(Cl)c1>>OCc1cc(Cl)c(I)c(Cl)c1 -US04587046,2,CC(=O)CCCCC(=O)O.CC(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)NCC(=O)OCc1ccccc1>>CC(=O)CCCCC(=O)Nc1ccc(C[C@H](NC(C)=O)C(=O)NCC(=O)OCc2ccccc2)cc1 -US20080004312A1,1,CS(=O)(=O)OCCS(=O)(=O)c1cccc([N+](=O)[O-])c1.c1ccc(CC2CCNCC2)cc1>>O=[N+]([O-])c1cccc(S(=O)(=O)CCN2CCC(Cc3ccccc3)CC2)c1 -US06867185B2,6,CCOC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](Oc3cc(-c4ccccc4)nc4cc(OC)ccc34)C[C@H]1C(=O)N2>>COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)O)C[C@H]5C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N4C3)cc(-c3ccccc3)nc2c1 -US20120034270A1,3,C#CC1(NC(=O)OC(C)(C)C)COC(C)(C)OC1.Ic1ccc(I)cc1>>CC(C)(C)OC(=O)NC1(C#Cc2ccc(I)cc2)COC(C)(C)OC1 -US04753933,2,CN(C)CCOc1ccc2ccc(N)nc2n1.O=C(O)c1ccccc1>>CN(C)CCOc1ccc2ccc(NC(=O)c3ccccc3)nc2n1 -US20100004280A1,2,CCC(C)(C)CC(O)CN.COC(=O)C(Cc1ccc(-c2cn(C)nc2NC(=O)OC(C)(C)C)cc1)NC(C)=O>>CCC(C)(C)CC(O)CNC(=O)C(Cc1ccc(-c2cn(C)nc2NC(=O)OC(C)(C)C)cc1)NC(C)=O -US20050228017A1,9,COC(=O)COc1cc(CN(CCc2ccccn2)C(=O)c2ccccc2Cl)ccc1OCc1ccccc1.[NH4+]>>NC(=O)COc1cc(CN(CCc2ccccn2)C(=O)c2ccccc2Cl)ccc1OCc1ccccc1 -US06627651B1,6,COc1ccc(CN(C)C2CCOCC2)cc1>>CN(Cc1ccc(O)cc1)C1CCOCC1 -US05079264,1,CC(=O)c1ccc(F)cc1Cl.CN>>CNc1cc(F)ccc1C(C)=O -US20150133512A1,3,CCc1nnn(-c2ccc(Br)cc2)c1NC(=O)O[C@H](C)c1ccccc1.COC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1>>CCc1nnn(-c2ccc(-c3ccc(C4(C(=O)OC)CC4)cc3)cc2)c1NC(=O)O[C@H](C)c1ccccc1 -US20150239893A1,2,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)O.Nc1cccc(Br)n1>>CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)Nc1cccc(Br)n1 -US08022062B2,7,CC(C)(C)COCc1ccc(C#N)cc1>>CC(C)(C)COCc1ccc(CN)cc1 -US08598173B2,2,CCOC(=O)Nc1nc2cc(C)c(C)cc2nc1OC.COc1cc(OC)cc(N2CCNCC2)c1>>COc1cc(OC)cc(N2CCN(C(=O)Nc3nc4cc(C)c(C)cc4nc3OC)CC2)c1 -US08981084B2,2,COc1ccccc1N1CCNCC1.O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1>>COc1ccccc1N1CCN(C(=O)c2cccc(-c3noc(C(F)(F)F)n3)c2)CC1 -US20120264735A1,1,CCOc1cnc(-c2cccc(O)c2)nc1.Cn1cc(-n2ccc(=O)c(Cl)n2)cn1>>CCOc1cnc(-c2cccc(Oc3nn(-c4cnn(C)c4)ccc3=O)c2)nc1 -US20040180934A1,7,C=C(C)c1cc(F)cc2c1cc1n2CCC1CC(=O)OC>>COC(=O)CC1CCn2c1cc1c(C(C)C)cc(F)cc12 -US20060264460A1,2,N#Cc1cnc2c(Cl)cc(NCc3cn(CC(=O)O)nn3)cc2c1Nc1ccc(F)c(Cl)c1.NCc1ccccn1>>N#Cc1cnc2c(Cl)cc(NCc3cn(CC(=O)NCc4ccccn4)nn3)cc2c1Nc1ccc(F)c(Cl)c1 -US20070293492A1,3,CC(C)(C)OC(=O)Nc1ccc2ncccc2c1Br.Cc1ccccc1B(O)O>>Cc1ccccc1-c1c(NC(=O)OC(C)(C)C)ccc2ncccc12 -US06403626B1,3,CCCC[Sn](CCCC)(CCCC)CCCC.Nc1c(Br)cc([N+](=O)[O-])cc1[N+](=O)[O-]>>CCCCc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1N -US06420390B1,1,CC(=O)c1ccc2c(c1)oc(=O)n2CCCCl.Fc1ccc2c(C3CCNCC3)noc2c1>>CC(=O)c1ccc2c(c1)oc(=O)n2CCCN1CCC(c2noc3cc(F)ccc23)CC1 -US20100152443A1,2,CCN=C=O.CCc1cc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)n[nH]1>>CCNC(=O)n1nc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)cc1CC -US08003649B2,1,CCOC(=O)c1cccc(C2CCNCC2)c1.FC(F)(F)c1nnc2ccc(Cl)nn12>>CCOC(=O)c1cccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)c1 -US04761501,7,CN(C)C(=O)C(c1ccc(N)cc1)C1(O)CCCCC1>>CN(C)CC(c1ccc(N)cc1)C1(O)CCCCC1 -US20150191439A1,3,Brc1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1.CSc1ccccc1B(O)O>>CSc1ccccc1-c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1 -US07074819B2,8,O=S([O-])OO.Oc1ccc(C2COc3cc(O)ccc3C2CCCCCCCCCSCCCC(F)(F)C(F)(F)F)cc1>>O=S(CCCCCCCCCC1c2ccc(O)cc2OCC1c1ccc(O)cc1)CCCC(F)(F)C(F)(F)F -US20090247559A1,6,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1c(C(N)=O)oc2ccc(Br)cc12>>NC(=O)c1oc2ccc(Br)cc2c1NC(=O)[C@@H](N)Cc1ccccc1 -US20140332758A1,3,Clc1ncc(Br)cn1.OB(O)c1ccccc1-c1ccccc1>>Clc1ncc(-c2ccccc2-c2ccccc2)cn1 -US20150080365A1,2,CC(C)/C=C/C(=O)O.Cc1ncccc1C1CCNCC1>>Cc1ncccc1C1CCN(C(=O)/C=C/C(C)C)CC1 -US20120196845A1,2,CC(=O)Cl.Cc1ccccc1-n1nc2c3c(O)cccc3n(Cc3ccc(-n4cccn4)cc3)cc-2c1=O>>CC(=O)Oc1cccc2c1c1nn(-c3ccccc3C)c(=O)c-1cn2Cc1ccc(-n2cccn2)cc1 -US08178522B2,2,C1COCCN1.Cc1onc(-c2ccc(F)cn2)c1/C=C/c1ncc(C(=O)O)s1>>Cc1onc(-c2ccc(F)cn2)c1/C=C/c1ncc(C(=O)N2CCOCC2)s1 -US06818644B1,1,COc1cccc(N2CCNCC2)n1.O=C(NCc1ccc(F)cc1)C1(CCCCBr)c2ccccc2-c2ccccc21>>COc1cccc(N2CCN(CCCCC3(C(=O)NCc4ccc(F)cc4)c4ccccc4-c4ccccc43)CC2)n1 -US20060040984A1,7,O=C(C1CC(O)C(O)C1)N1CCC(Oc2ccc(Cl)c(Cl)c2)CC1>>OC1CC(CN2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1O -US20150231132A1,2,CCOC(=O)CN1CCN(Cc2cc(OC)c(OC)c(OC)c2)CC1.NN>>COc1cc(CN2CCN(CC(=O)NN)CC2)cc(OC)c1OC -US07351857B2,2,CCNC1CCc2cc(SC(C)(C)C(=O)OC(C)(C)C)c(Cl)cc2C1.Cc1ccc(OC(=O)Cl)cc1>>CCN(C(=O)Oc1ccc(C)cc1)C1CCc2cc(SC(C)(C)C(=O)OC(C)(C)C)c(Cl)cc2C1 -US20120101100A1,3,CC1(C)OB(c2cnn(CCN3CCOCC3)c2)OC1(C)C.CCNC(=O)Nc1cc(Br)c(-c2cncc(-c3n[nH]c(=O)o3)c2)cn1>>CCNC(=O)Nc1cc(-c2cnn(CCN3CCOCC3)c2)c(-c2cncc(-c3n[nH]c(=O)o3)c2)cn1 -US20090111778A1,3,CC(C)(C)OC(=O)N1CCC(CCCC(=O)Cl)CC1.c1cocn1>>CC(C)(C)OC(=O)N1CCC(CCCC(=O)c2ncco2)CC1 -US07649093B2,6,CCCc1cc2cc(OC)c(F)cc2c(Oc2ccc(/C=C/C(=O)O)cc2)c1-c1ccccc1>>CCCc1cc2cc(O)c(F)cc2c(Oc2ccc(/C=C/C(=O)O)cc2)c1-c1ccccc1 -US04816582,2,NC(=O)OC[C@@H]1[C@H](N)C(=O)N1S(=O)(=O)O.[N-]=[N+]=NCCO/N=C(\C(=O)O)c1csc(N)n1>>[N-]=[N+]=NCCO/N=C(\C(=O)N[C@@H]1C(=O)N(S(=O)(=O)O)[C@@H]1COC(N)=O)c1csc(N)n1 -US20040023961A1,1,CC(C)(C)OC(=O)Nc1ccc(O)c2ccccc12.ClCc1ccncc1>>CC(C)(C)OC(=O)Nc1ccc(OCc2ccncc2)c2ccccc12 -US20080312292A1,1,CCCCn1c2c(cc(O)c1=O)CCCC2.Clc1nc2ccccc2o1>>CCCCn1c2c(cc(Oc3nc4ccccc4o3)c1=O)CCCC2 -US20120208792A1,1,N#Cc1ccc2c(c1)nc(Cl)c1ccsc12.Oc1ccccc1>>N#Cc1ccc2c(c1)nc(Oc1ccccc1)c1ccsc12 -US20020177589A1,1,CNC(C)(C)C.CS(=O)(=O)OCCc1cc2cc(-c3ccc(C(=O)N4CCOCC4)cn3)ccc2o1>>CN(CCc1cc2cc(-c3ccc(C(=O)N4CCOCC4)cn3)ccc2o1)C(C)(C)C -US20080275018A1,2,CC(C)(C)OC(=O)NCCN.CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)CC(=O)O>>CC(C)(C)OC(=O)NCCNC(=O)C[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C -US20100227880A1,7,CCOC(=O)c1nc2ccccn2c1-c1ccc(N2CCN(C)CC2)nc1>>CN1CCN(c2ccc(-c3c(CO)nc4ccccn34)cn2)CC1 -US20100010035A1,3,COC(=O)c1ccc(Br)c(OCC(C)C)c1.COCCOCN(c1noc(C)c1C)S(=O)(=O)c1sc(C)cc1B(O)O>>COCCOCN(c1noc(C)c1C)S(=O)(=O)c1sc(C)cc1-c1ccc(C(=O)OC)cc1OCC(C)C -US06432950B1,1,CCc1cc2c(NCc3ccc(F)cc3)nc(Cl)nc2s1.Cc1ncc[nH]1>>CCc1cc2c(NCc3ccc(F)cc3)nc(-n3ccnc3C)nc2s1 -US07273877B2,7,Cn1cc(C(=O)NCCO)c(Nc2ccc(C#CCO)cc2F)cc1=O>>Cn1cc(C(=O)NCCO)c(Nc2ccc(CCCO)cc2F)cc1=O -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)c1cccc(OC(F)(F)F)c1>>Cc1nc(NC(=O)c2cccc(OC(F)(F)F)c2)sc1C(=O)NCc1ccccc1 -US20140155406A1,2,C=CC(=O)O.CCCc1ccnc(NC(=O)c2ccc(-c3nc([C@@H]4CCCCN4)n4ccnc(C)c34)cc2)c1>>C=CC(=O)N1CCCC[C@H]1c1nc(-c2ccc(C(=O)Nc3cc(CCC)ccn3)cc2)c2c(C)nccn12 -US06413964B1,8,Cn1cncc1C(CCCO)(NS(=O)C(C)(C)C)c1ccc(C#N)c(F)c1>>Cn1cncc1C(CCC=O)(NS(=O)C(C)(C)C)c1ccc(C#N)c(F)c1 -US07531553B2,6,CNC(=O)c1cc(Oc2ccc3[nH]c(Nc4ccc5c(c4)CN(C(=O)OC(C)(C)C)CC5(C)C)nc3c2)ccn1>>CNC(=O)c1cc(Oc2ccc3[nH]c(Nc4ccc5c(c4)CNCC5(C)C)nc3c2)ccn1 -US04486443,1,CCOC(=O)CCCCBr.CCOC(=O)[C@@H](N)CS>>CCOC(=O)CCCCSC[C@H](N)C(=O)OCC -US20090082434A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(OS(=O)(=O)C(F)(F)F)c3O2)cc1.OB(O)c1ccc(F)c(Cl)c1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4ccc(F)c(Cl)c4)c3O2)cc1 -US20070021414A1,1,O=C(CCl)c1ccc(O)c(F)c1.OC1(c2cccc(F)c2)CCNCC1>>O=C(CN1CCC(O)(c2cccc(F)c2)CC1)c1ccc(O)c(F)c1 -US08178522B2,2,Cc1nc(CCc2c(-c3ccc(F)cn3)noc2C)sc1C(=O)O.NC1CC1>>Cc1nc(CCc2c(-c3ccc(F)cn3)noc2C)sc1C(=O)NC1CC1 -US20090247567A1,1,CN(C(=O)c1cc2c(s1)-c1ccc(CBr)cc1OCC2)c1ccccc1Cl.CN(C)CCN>>CN(C)CCNCc1ccc2c(c1)OCCc1cc(C(=O)N(C)c3ccccc3Cl)sc1-2 -US20110263607A1,6,CCOC(CN(Cc1ccc(F)cc1F)C(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21)OCC>>CCOC(CN(Cc1ccc(F)cc1F)C(=O)[C@@H](N)Cc1ccc(OC(C)(C)C)cc1)OCC -US20100280016A1,3,CC(=O)Nc1ccc2c(c1)CCCC2=O.O=CC1CCCC1>>CC(=O)Nc1ccc2c(c1)CC/C(=C\C1CCCC1)C2=O -US20120028970A1,1,Cc1nc(SCc2cc(N3CCSCC3)cc(NC(=O)OC(C)(C)C)n2)oc1C.Fc1cccc(CCl)n1>>Cc1nc(SCc2cc(N3CCSCC3)cc(N(Cc3cccc(F)n3)C(=O)OC(C)(C)C)n2)oc1C -US20110098296A1,1,CN(C)CCOc1ccc(N)cc1F.Cc1nc(-c2cccc(NC(=O)c3c(F)cccc3F)c2)c(-c2ccnc(Cl)n2)s1>>Cc1nc(-c2cccc(NC(=O)c3c(F)cccc3F)c2)c(-c2ccnc(Nc3ccc(OCCN(C)C)c(F)c3)n2)s1 -US20100184809A1,2,COC(=O)c1ccc(S(=O)(=O)Cl)cc1.Cc1nc(OCc2c(-c3c(Cl)cccc3Cl)noc2C(C)C)ccc1N>>COC(=O)c1ccc(S(=O)(=O)Nc2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C(C)C)nc2C)cc1 -US06432993B1,7,Cc1ccc(Sc2ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c2)cc1>>Cc1ccc(Sc2ccc(N)c(N(C)C(=O)OC(C)(C)C)c2)cc1 -US05455260,1,ICCCCCCc1ccccc1.NCCOCc1ccc(-c2nc3ccccc3o2)cc1>>c1ccc(CCCCCCNCCOCc2ccc(-c3nc4ccccc4o3)cc2)cc1 -US07704994B2,1,Ic1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1.O=C1NCCO1>>O=C1OCCN1c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1 -US05491167,1,CCC(Oc1ccc(F)cc1)C(=O)O.C[C@H]1C=CC2=C[C@@H](C(C)(C)C)C[C@H](O)[C@@H]2[C@@]1(CC[C@@H]1C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O1)O[SiH](C)C>>CCC(Oc1ccc(F)cc1)C(=O)O[C@H]1C[C@H](C(C)(C)C)C=C2C=C[C@H](C)[C@](CC[C@@H]3C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O3)(O[SiH](C)C)[C@H]21 -US20150038528A1,2,COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O.NC[C@H](Cc1ccccc1)C(=O)O>>N#Cc1nc(C(=O)NC[C@H](Cc2ccccc2)C(=O)O)c(O)c2ccc(Oc3ccccc3)cc12 -US20150119362A1,1,C[C@H](O)Cc1ccc(N)cc1.Clc1cccc(-c2cc(Cl)c3c(n2)CCC3)c1>>C[C@H](O)Cc1ccc(Nc2cc(-c3cccc(Cl)c3)nc3c2CCC3)cc1 -US05866564,2,COc1ccc(CS[C@H]2C[C@@H](C(=O)O)N(C)C2)cc1.N=C(NC(=O)OCc1ccc([N+](=O)[O-])cc1)N1CCNCC1>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(C(=N)NC(=O)OCc4ccc([N+](=O)[O-])cc4)CC3)N(C)C2)cc1 -US07795283B2,2,COC(=O)C(=O)Nc1ccc(N2CCC(C(=O)OC)CC2)nc1.NN>>COC(=O)C1CCN(c2ccc(NC(=O)C(=O)NN)cn2)CC1 -US08987473B2,1,Cc1ccc(C)c(CCl)c1.Cc1n[nH]c2cc(Br)ccc12>>Cc1ccc(C)c(Cn2nc(C)c3ccc(Br)cc32)c1 -US20140018368A1,2,COC(=O)c1cnc(-c2cc(NC(=O)c3ccc(S(C)(=O)=O)cc3Cl)ccc2Cl)nc1.NO>>CS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ncc(C(=O)NO)cn3)c2)c(Cl)c1 -US05256645,2,CC(C)(C)C(=O)C[C@@H](Cc1ccccc1)C(=O)O.CCC(CC)C(O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](N)Cc1c[nH]cn1>>CCC(CC)C(O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](CC(=O)C(C)(C)C)Cc1ccccc1 -US20030114666A1,9,C[C@@H](c1ccccc1)N1CC(C(=O)c2ccccc2F)CC1=O.NO>>C[C@@H](c1ccccc1)N1CC(C(=NO)c2ccccc2F)CC1=O -US04089960,2,CCN1CCCC1CN.COc1nc(Cl)ccc1C(=O)Cl>>CCN1CCCC1CNC(=O)c1ccc(Cl)nc1OC -US06140265,3,Cc1ccc(B(O)O)cc1.N#Cc1ccccc1Cl>>Cc1ccc(-c2ccccc2C#N)cc1 -US08921388B2,2,CCOC(=O)c1nc(CC2(c3ccccc3)CCCC2)n(C)c(=O)c1O.CN>>CNC(=O)c1nc(CC2(c3ccccc3)CCCC2)n(C)c(=O)c1O -US20110172442A1,6,COC(=O)[C@H](Cc1cn(C)c2ccccc12)NC(=O)C=Cc1ccccc1F>>Cn1cc(C[C@H](NC(=O)C=Cc2ccccc2F)C(=O)O)c2ccccc21 -US07129232B2,1,CCOC(=O)CC(=O)Nc1cnn(C)c1N.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)CC(=O)Nc1cnn(C)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20050096380A1,6,CCOC(=O)/C=C(C)/C=C/C(F)=C(/CC)c1cc2c(cc1OCC)C(C)(C)CC=C2C(C)(C)C>>CCOc1cc2c(cc1/C(CC)=C(F)\C=C\C(C)=C\C(=O)O)C(C(C)(C)C)=CCC2(C)C -US07425554B2,6,CCC1(CC)CCC(c2cc(N3CCC[C@H](OC)C3)ccc2N2CCN(C(=O)OC(C)(C)C)CC2)CC1>>CCC1(CC)CCC(c2cc(N3CCC[C@H](OC)C3)ccc2N2CCNCC2)CC1 -US20090111867A1,6,Cc1c(C2=NN(Cc3cccc(C(F)(F)F)c3)S(=O)(=O)c3ccccc32)c2cc(F)ccc2n1CC(=O)OC(C)(C)C>>Cc1c(C2=NN(Cc3cccc(C(F)(F)F)c3)S(=O)(=O)c3ccccc32)c2cc(F)ccc2n1CC(=O)O -US08476253B2,6,COC(=O)c1sc(NC(=O)OC(C)(C)C)cc1C>>Cc1cc(NC(=O)OC(C)(C)C)sc1C(=O)O -US20110269738A1,1,CCc1c(C=O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C#N)c2)s1.O=C(O)[C@@H]1CCCN1>>CCc1c(CN2CCC[C@H]2C(=O)O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C#N)c2)s1 -US05086074,1,CI.O=C1CCc2cc(O)c(I)cc21>>COc1cc2c(cc1I)C(=O)CC2 -US07763610B2,1,CCOC(=O)C1CN(CCCC(=O)OC)c2cccc(N)c2O1.O=Cc1ccc(OCCCCc2ccccc2)cc1>>CCOC(=O)C1CN(CCCC(=O)OC)c2cccc(NCc3ccc(OCCCCc4ccccc4)cc3)c2O1 -US06388061B1,3,C=CCN.O=C(Cl)OCc1ccccc1>>NCC=CC(=O)OCc1ccccc1 -US20070231263A1,2,CCOC(=O)c1csc(C2CCNCC2)n1.O=C(O)Cc1ccccc1Cl>>CCOC(=O)c1csc(C2CCN(C(=O)Cc3ccccc3Cl)CC2)n1 -US20150283134A1,3,CON(C)C(=O)C1(c2cnc(C)nc2)CCOCC1.C[Mg+]>>CC(=O)C1(c2cnc(C)nc2)CCOCC1 -US20150011551A1,2,COc1ccc(Br)cc1S(=O)(=O)Nc1cncc(C(=O)O)c1.NC1CCCCC1>>COc1ccc(Br)cc1S(=O)(=O)Nc1cncc(C(=O)NC2CCCCC2)c1 -US20110201650A1,8,OCC1(COCc2ccccc2)CCC2(CC1)OCCO2>>O=CC1(COCc2ccccc2)CCC2(CC1)OCCO2 -US07179934B2,2,CCCCC(=O)O.C[C@@H]1NC(=O)O[C@@H]1c1ccccc1>>CCCCC(=O)N1C(=O)O[C@H](c2ccccc2)[C@@H]1C -US20140315881A1,9,Cc1ccc(C(NC(=O)Cc2ccc3oc(C(Cl)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1.N>>Cc1ccc(C(NC(=O)Cc2ccc3oc(C(N)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1 -US20130109682A1,3,CC(=O)Nc1cc(F)c(B2OC(C)(C)C(C)(C)O2)c(F)c1.C[C@H]1O[C@@H](c2ccncc2NC(=O)c2ccc(F)c(Br)n2)C[C@@H](NC(=O)OC(C)(C)C)[C@]1(C)O>>CC(=O)Nc1cc(F)c(-c2nc(C(=O)Nc3cnccc3[C@H]3C[C@@H](NC(=O)OC(C)(C)C)[C@](C)(O)[C@@H](C)O3)ccc2F)c(F)c1 -US20150152047A1,1,CCOC(=O)c1ccc(C=O)c(OC(F)(F)F)c1.CN(C(=O)OC(C)(C)C)[C@H]1CCCNC1>>CCOC(=O)c1ccc(CN2CCC[C@H](N(C)C(=O)OC(C)(C)C)C2)c(OC(F)(F)F)c1 -US08680091B2,7,N#Cc1ccc(OC2CCCCC2)nc1>>NCc1ccc(OC2CCCCC2)nc1 -US08106215B2,2,CC1C[C@H]2CN[C@H](CNC(=O)c3nsc4ccccc34)[C@H]2C1.Cc1cccc(-c2sc(C)nc2C(=O)O)c1>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(C)C[C@@H]3[C@H]2CNC(=O)c2nsc3ccccc23)c1 -US20010039286A1,3,CCCC[Sn](CCCC)(CCCC)c1cccnc1.Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCC(O)(Cc3ccccc3)CC2)c2cc(Br)ccc21>>Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCC(O)(Cc3ccccc3)CC2)c2cc(-c3cccnc3)ccc21 -US20060074237A1,1,O=[N+]([O-])c1ccc(Br)cn1.Oc1ccccc1>>O=[N+]([O-])c1ccc(Oc2ccccc2)cn1 -US20070225292A1,2,COC(=O)c1nccnc1N.COc1ccc(C(=O)Cl)c2ccccc12>>COC(=O)c1nccnc1NC(=O)c1ccc(OC)c2ccccc12 -US08841334B2,1,COCCn1c(=N)sc2cc(F)ccc21.O=C(Cl)CC1CCCC1>>COCCn1/c(=N/C(=O)CC2CCCC2)sc2cc(F)ccc21 -US20130231306A1,7,CCCP(=O)(CCC)c1cccc([N+](=O)[O-])c1>>CCCP(=O)(CCC)c1cccc(N)c1 -US04389409,1,C=CCS.Clc1ccc(CC(Cl)n2ccnc2)c(Cl)c1>>C=CCSC(Cc1ccc(Cl)cc1Cl)n1ccnc1 -US08334381B2,4,Cc1ccc(N)cc1NC(=N)N.O=CCC(=O)c1cccnc1>>Cc1ccc(N)cc1Nc1nccc(-c2cccnc2)n1 -US06143764,6,CCOC(=O)c1cccc(NC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)c1>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4cccc(C(=O)O)c4)cc3)c2cc1OC -US07125900B2,2,CC(=O)c1sc(N)nc1C.Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Cl>>CC(=O)c1sc(NS(=O)(=O)c2c(C)cc(Cl)cc2Cl)nc1C -US20150031674A1,1,CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CCN3CCNCC3)c2n1.O=C1COC1>>CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CCN3CCN(C4COC4)CC3)c2n1 -US20150274720A1,1,CC(C)(C)OC(=O)N1CCNCC1.COc1cncc2nc(-c3ccnc(Cl)c3)nc(O)c12>>COc1cncc2nc(-c3ccnc(Cl)c3)nc(N3CCN(C(=O)OC(C)(C)C)CC3)c12 -US06528528B2,2,COc1ccc(C(=O)Nc2ccccc2)cc1N.S=C=Nc1ccc(Cl)cc1>>COc1ccc(C(=O)Nc2ccccc2)cc1NC(=S)Nc1ccc(Cl)cc1 -US20100261710A1,2,CCOC(=O)CCCCCCNCc1ccccc1.O=C(O)c1cn2c3c(cccc13)CCC2>>CCOC(=O)CCCCCCN(Cc1ccccc1)C(=O)c1cn2c3c(cccc13)CCC2 -US20070105852A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccsc1>>CC(C)(C)OC(=O)Nc1ccsc1 -US04988809,1,O=C1c2cc(F)ccc2S(=O)(=O)N1CCCCBr.c1cnc(N2CCNCC2)nc1>>O=C1c2cc(F)ccc2S(=O)(=O)N1CCCCN1CCN(c2ncccn2)CC1 -US20050245529A1,6,C/C(=C\[C@@H](C)NC(=O)OC(C)(C)C)c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1>>C/C(=C\[C@@H](C)N)c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1 -US20080176830A1,3,COC(=O)c1cc(Br)ccc1N.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)ccc1N -US04167638,1,COc1cc(N)c2nccc(C)c2c1.O=C1c2ccccc2C(=O)N1CCCCCCBr>>COc1cc(NCCCCCCN2C(=O)c3ccccc3C2=O)c2nccc(C)c2c1 -US07371748B2,1,C1CCNC1.COc1ccc(C2COCCOC2)c2sc(NC(=O)c3ccc(CCl)cc3)nc12>>COc1ccc(C2COCCOC2)c2sc(NC(=O)c3ccc(CN4CCCC4)cc3)nc12 -US08492378B2,2,CS(=O)(=O)Cl.Cc1nnc(-c2ccc3occ(-c4ccc(O)cc4)c3c2)o1>>Cc1nnc(-c2ccc3occ(-c4ccc(OS(C)(=O)=O)cc4)c3c2)o1 -US07772270B2,2,Nc1ccc(-c2ccc(S(=O)(=O)N3C(C(=O)O)CC4CCCC43)cc2)cc1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1ccc(-c2ccc(S(=O)(=O)N3C(C(=O)O)CC4CCCC43)cc2)cc1 -US04921997,2,CC(C)(Oc1ccc(N)cc1)C(=O)O.O=C=Nc1cc(Cl)cc(Cl)c1>>CC(C)(Oc1ccc(NC(=O)Nc2cc(Cl)cc(Cl)c2)cc1)C(=O)O -US08357707B2,6,CC(=O)Nc1nc2c(s1)-c1nc(C(C)(C)C)sc1CC2>>CC(C)(C)c1nc2c(s1)CCc1nc(N)sc1-2 -US20140371209A1,6,CCOC(=O)C1CCN(Cc2ccc3cc(CC4CCC(C(C)(C)C)CC4)ccc3c2)CC1>>CC(C)(C)C1CCC(Cc2ccc3cc(CN4CCC(C(=O)O)CC4)ccc3c2)CC1 -US06762205B1,2,C[SiH](C)OC(Nc1ccc(C#N)cc1)c1ccc(C(C)(C)C)cc1.O=C(Cl)c1cccs1>>C[SiH](C)OC(c1ccc(C(C)(C)C)cc1)N(C(=O)c1cccs1)c1ccc(C#N)cc1 -US20150274718A1,3,CCCc1cccc(Br)n1.COC(=O)C(OC(C)(C)C)c1c(C(F)(F)F)ccc(B2OC(C)(C)C(C)(C)O2)c1-c1ccc2c(c1)CCCO2>>CCCc1cccc(-c2ccc(C(F)(F)F)c(C(OC(C)(C)C)C(=O)OC)c2-c2ccc3c(c2)CCCO3)n1 -US08518972B2,1,FC(F)(F)CN1CCNCC1.O=C1CC[C@H](N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1>>O=C1CCC(N2Cc3c(OCc4ccc(CN5CCN(CC(F)(F)F)CC5)cc4)cccc3C2=O)C(=O)N1 -US20130253186A1,1,C1COCCN1.Fc1ncccc1I>>Fc1ncccc1N1CCOCC1 -US20080306115A1,2,Cc1c(C(=O)Cl)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCCC(F)(F)F)cc1.N[C@H]1CCCC[C@H]1O>>Cc1c(C(=O)N[C@@H]2CCCC[C@@H]2O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCCC(F)(F)F)cc1 -US20090005353A1,6,CC(C)(C)OC(=O)NC1CN(c2ncc(C(F)(F)F)cc2Cl)C1>>NC1CN(c2ncc(C(F)(F)F)cc2Cl)C1 -US06197959B1,1,CN.COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)N(CCOS(C)(=O)=O)CCC3)cc1>>CNCCN1CCCc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)CC[C@@H]3c3ccc(OCCCOCc4ccccc4OC)cc3)cc21 -US07750014B2,2,COC(=O)Cc1cnc(Cc2ccc(N)cc2)n2ccnc12.O=C(Cl)c1ccc(C(F)(F)F)cc1>>COC(=O)Cc1cnc(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)n2ccnc12 -US20130296363A1,6,Cc1cc(Nc2nc(S(=O)c3ccc(F)cc3)cc3ccccc23)nn1C(=O)OC(C)(C)C>>Cc1cc(Nc2nc(S(=O)c3ccc(F)cc3)cc3ccccc23)n[nH]1 -US20080318923A1,1,COC(=O)[C@@H]1C[C@H](F)CN1.COc1ccccc1C1(Cl)C(=O)Nc2ccc(Cl)cc21>>COC(=O)[C@@H]1C[C@H](F)CN1C1(c2ccccc2OC)C(=O)Nc2ccc(Cl)cc21 -US20120149721A1,2,CC(=O)Cl.Cc1[nH]c2c(-c3cc(C(F)F)ccc3OCC3CC3)ncnc2c1C(=O)N[C@H]1CC[C@H](N)C[C@@H]1C>>CC(=O)N[C@H]1CC[C@H](NC(=O)c2c(C)[nH]c3c(-c4cc(C(F)F)ccc4OCC4CC4)ncnc23)[C@@H](C)C1 -US08217037B2,2,CC(=O)Cl.Nc1ccccc1C(=O)O>>CC(=O)Nc1ccccc1C(=O)O -US08664220B2,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1NC1CCN(Cc2ccccc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC4CCN(Cc5ccccc5)CC4)cc3)cc2)CC1 -US20130090323A1,3,Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1Br.OB(O)c1cccnc1>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1cccnc1 -US20130237525A1,2,COc1cccc(OC)c1C(CO)NCc1ccc(OC(F)(F)F)cc1.O=C(Cl)CCl>>COc1cccc(OC)c1C(CO)N(Cc1ccc(OC(F)(F)F)cc1)C(=O)CCl -US05883098,2,O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCNC[C@H]1Cc1c[nH]c2ccccc12.O=C=NC1CCCCC1>>O=C(NC1CCCCC1)N1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2c[nH]c3ccccc23)C1 -US20060247439A1,1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](OS(C)(=O)=O)C1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@H]1CC[C@H](N=[N+]=[N-])C1 -US20150218181A1,6,CC(C)(C)OC(=O)N1CCn2c(Br)nnc2C1>>Brc1nnc2n1CCNC2 -US05229398,1,Clc1nc2ccccc2s1.OCC1CCNCC1>>OCC1CCN(c2nc3ccccc3s2)CC1 -US04925862,7,CCOC(=O)c1sc(=O)n(Cc2ccccc2)c1C(F)(F)F>>O=c1sc(CO)c(C(F)(F)F)n1Cc1ccccc1 -US04661481,2,NCCCN1CCN(Cc2ccc(Cl)cc2)CC1.O=C=NC1CCCCC1>>O=C(NCCCN1CCN(Cc2ccc(Cl)cc2)CC1)NC1CCCCC1 -US20150183775A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.NS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(S(N)(=O)=O)cc2[N+](=O)[O-])CC1 -US20090227786A1,6,O=C1[C@H](CCC2(c3ccc(F)cc3)OCCO2)[C@@H](c2ccc(OCc3ccccc3)cc2)N1c1ccc(F)cc1>>O=C(CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(OCc2ccccc2)cc1)c1ccc(F)cc1 -US05008290,2,Cn1cccc1CCN.O=S(=O)(Cl)Cc1ccccc1>>Cn1cccc1CCNS(=O)(=O)Cc1ccccc1 -US06777407B2,6,COC(=O)[C@H](CO)NC(=O)c1cccc2c1NC1CCCC21>>O=C(N[C@@H](CO)C(=O)O)c1cccc2c1NC1CCCC21 -US20050014754A1,7,O=C(c1ccc(F)cc1)c1ccn2ccccc12>>Fc1ccc(Cc2ccn3ccccc23)cc1 -US08188301B2,1,CCI.OC1(c2cccc(Cl)c2F)CCNC1>>CCN1CCC(O)(c2cccc(Cl)c2F)C1 -US20080193413A1,3,C=C[Mg+].CC(C)(C)CC=O>>C=CC(O)CC(C)(C)C -US20110224204A1,3,CC1(C)OB(c2ccc(OCc3ccc4ccccc4n3)cc2)OC1(C)C.O=S(=O)(Oc1ccc(Cl)cc1-c1ccncc1)C(F)(F)F>>Clc1ccc(-c2ccc(OCc3ccc4ccccc4n3)cc2)c(-c2ccncc2)c1 -US06589950B1,7,CCC(=O)N(C)c1ccc([N+](=O)[O-])cc1>>CCC(=O)N(C)c1ccc(N)cc1 -US08003662B2,3,C#CCN1CCOCC1.Nc1ccc(Oc2ccnc3cc(I)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(C#CCN4CCOCC4)sc23)c(F)c1 -US08012979B2,2,COC(=O)c1ccc(C)c(-c2ccc3c(=O)n(Cc4ccc(OC)cc4)ccc3c2)c1.NC1CC1>>COc1ccc(Cn2ccc3cc(-c4cc(C(=O)NC5CC5)ccc4C)ccc3c2=O)cc1 -US07371749B2,2,CCOC(=O)c1cnn(CCN2CCCC2)c1.COc1ccc(N2CCOCC2)c2sc(N)nc12>>COc1ccc(N2CCOCC2)c2sc(NC(=O)c3cnn(CCN4CCCC4)c3)nc12 -US20090018131A1,3,Brc1ccc2ncnc(N3CCOCC3)c2c1.O=S(=O)(Nc1cncc(Br)c1)C1CCNCC1>>O=S(=O)(Nc1cncc(-c2ccc3ncnc(N4CCOCC4)c3c2)c1)C1CCNCC1 -US08426101B2,1,CC1CCC(C(C)C)C(OCCl)C1.O=C(O)c1ccc(O)cc1>>CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OCOC(=O)c1ccc(O)cc1 -US08563547B2,6,CC(C)(C)OC(=O)N1CCC(Oc2ccc(OC(F)(F)F)cc2)CC1>>FC(F)(F)Oc1ccc(OC2CCNCC2)cc1 -US20140142083A1,1,COC(=O)c1cc(Br)cc(N)c1C.O=C1CCCC1>>COC(=O)c1cc(Br)cc(NC2CCCC2)c1C -US20100113780A1,1,CC(C)(C)[Si](C)(C)OCCBr.CCCCc1nc(C)n(-c2cccc(O)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCCc1nc(C)n(-c2cccc(OCCO[Si](C)(C)C(C)(C)C)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20140142085A1,1,CC(C)(C)[S@@](N)=O.O=Cc1nccnc1-c1ccc(Cl)cc1>>CC(C)(C)S(=O)N=Cc1nccnc1-c1ccc(Cl)cc1 -US06028096,1,C=CCBr.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1C(=O)C(F)(F)F>>C=CCNc1c(C(=O)C(F)(F)F)c(C#N)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl -US08138168B1,4,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)O)C1.Cc1cccc(N)c1N>>Cc1cccc2[nH]c([C@@H]3CCCN(C(=O)OC(C)(C)C)C3)nc12 -US20140275129A1,2,COc1ccc2c(c1)CCNC2.O=C(O)c1nc(-c2ccc(F)cc2)nc2ccc(F)cc12>>COc1ccc2c(c1)CCN(C(=O)c1nc(-c3ccc(F)cc3)nc3ccc(F)cc13)C2 -US20120181523A1,3,Brc1c2ccccc2cc2ccccc12.OB(O)c1ccccc1>>c1ccc(-c2c3ccccc3cc3ccccc23)cc1 -US20110124642A1,2,Nn1nc(-c2ccccc2)c2cc(F)ccc2c1=O.O=C(O)Cc1ccc(Cl)cc1>>O=C(Cc1ccc(Cl)cc1)Nn1nc(-c2ccccc2)c2cc(F)ccc2c1=O -US20060074084A1,2,CC(C)(C)c1ccc(S(=O)(=O)O)cc1.Nc1ccc2[nH]c(C(=O)N3CCCC3)c(-c3ccccc3)c2c1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)N4CCCC4)c(-c4ccccc4)c3c2)cc1 -US20110257151A1,6,COC(=O)c1cc(Cl)cc2c1NC(c1cccc(N3CCN(c4ccccc4C)CC3)c1)C(C)(C)C2>>Cc1ccccc1N1CCN(c2cccc(C3Nc4c(cc(Cl)cc4C(=O)O)CC3(C)C)c2)CC1 -US04165231,9,Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1C(=O)O.N>>Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1C(N)=O -US20110086895A1,7,COC(=O)c1ccc(S(=O)(=O)Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)cc1>>O=[N+]([O-])c1ccc(NS(=O)(=O)c2ccc(CO)cc2)cc1C(F)(F)F -US20110092461A1,2,Cc1cc(S(C)(=O)=O)ccc1C(=O)O.Nc1ccc(Cl)c(-c2ccccn2)c1>>Cc1cc(S(C)(=O)=O)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1 -US20150080364A1,6,CC(C)(C)OC(=O)N1CCN(Cc2c(Cl)cccc2N2CCOCC2)CC1>>Clc1cccc(N2CCOCC2)c1CN1CCNCC1 -US20100273768A1,3,CC(C)(C)c1ccc2c(c1)NCCN(c1cccc(Br)c1C=O)C2=O.Cn1cc(B2OC(C)(C)C(C)(C)O2)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O>>Cn1cc(-c2cccc(N3CCNc4cc(C(C)(C)C)ccc4C3=O)c2C=O)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O -US07105544B2,2,CC(C(=O)O)c1ccc(Cl)cc1.CC(C)C(=O)Nc1cccc(C2CCN(CCCN)CC2)c1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCNC(=O)C(C)c3ccc(Cl)cc3)CC2)c1 -US20120142714A1,2,CC(=O)N[C@@H](C)COc1ccc(C(=O)O)cc1.CCCCC(CC)COC(=O)CCSc1cc(OCc2ccccc2)ccc1N>>CCCCC(CC)COC(=O)CCSc1cc(OCc2ccccc2)ccc1NC(=O)c1ccc(OC[C@H](C)NC(C)=O)cc1 -US20050171115A1,6,CC(C)(C)OC(=O)N1CCN(CC(c2cccc(-c3ccccc3F)c2)C2(O)CCCCC2)CC1>>OC1(C(CN2CCNCC2)c2cccc(-c3ccccc3F)c2)CCCCC1 -US20040088799A1,7,O=[N+]([O-])c1ccc(N2CCCC2CNCCO)cc1>>Nc1ccc(N2CCCC2CNCCO)cc1 -US03962443,6,CCOC(=O)c1cn(CC)c2nc(N3CCN(C(C)=O)CC3)ncc2c1=O>>CCn1cc(C(=O)O)c(=O)c2cnc(N3CCN(C(C)=O)CC3)nc21 -US05015666,1,ClCc1ccccc1.Oc1ccc(Br)cc1>>Brc1ccc(OCc2ccccc2)cc1 -US20120135995A1,3,CB1OB(C)OB(C)O1.COc1cc(OC)cc(-c2c(C)nnc(Cl)c2-c2c(F)cc(F)cc2F)c1>>COc1cc(OC)cc(-c2c(C)nnc(C)c2-c2c(F)cc(F)cc2F)c1 -US20140213448A1,6,CCN(C(=O)NC(=O)c1ccccc1)c1cn(-c2cccnc2)nc1Cl>>CCN(C(N)=O)c1cn(-c2cccnc2)nc1Cl -US20050154028A1,7,COc1ccc([N+](=O)[O-])cc1OCCN1CCCCC1>>COc1ccc(N)cc1OCCN1CCCCC1 -US20080275028A1,3,COc1ccccc1Br.O=C(O)c1ccc(B(O)O)cc1>>COc1ccccc1-c1ccc(C(=O)O)cc1 -US20100063080A1,2,C=C(C)CNCC.N#Cc1c(O)nc(SCc2cccc(F)c2F)nc1[C@@H]1C[C@H]1C(=O)O>>C=C(C)CN(CC)C(=O)[C@@H]1C[C@H]1c1nc(SCc2cccc(F)c2F)nc(O)c1C#N -US20060173204A1,6,COCCOC(Cc1ccc(OCCc2ccc(NC(=O)OC(C)(C)C)cc2)cc1)C(=O)OC>>COCCOC(Cc1ccc(OCCc2ccc(NC(=O)OC(C)(C)C)cc2)cc1)C(=O)O -US03968242,3,C1CCNC1.C=O.CC(=O)c1ccc(NS(C)(=O)=O)cc1>>CS(=O)(=O)Nc1ccc(C(=O)CCN2CCCC2)cc1 -US05602277,7,COC(=O)c1ccc(NC(C)=O)c(C=O)c1>>COC(=O)c1ccc(NC(C)=O)c(CO)c1 -US05627198,2,CC(O)(C(=O)O)C(F)(F)F.Nc1ccc(S(=O)(=O)c2ccccc2)s1>>CC(O)(C(=O)Nc1ccc(S(=O)(=O)c2ccccc2)s1)C(F)(F)F -US04968829,2,CC(C)=CCOc1ccc(OCCO)cc1.CC(C)N=C=O>>CC(C)=CCOc1ccc(OCCOC(=O)NC(C)C)cc1 -US20110021479A1,2,O=C(Cl)C1CC1.O=C(NC1CCNCC1)c1c[nH]c2c(-c3c(OCC4CCC4)ccc4c3OCO4)ncnc12>>O=C(NC1CCN(C(=O)C2CC2)CC1)c1c[nH]c2c(-c3c(OCC4CCC4)ccc4c3OCO4)ncnc12 -US20110183961A1,2,CCN1CCCC1CN.CS(=O)(=O)N(c1cccc(C(=O)O)c1)C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1>>CCN1CCCC1CNC(=O)c1cccc(N(C2CN(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)C2)S(C)(=O)=O)c1 -US08063038B2,6,Cc1cc(C(=O)N2CCCCc3ccccc32)ccc1CNC(=O)N1CC(=O)N(CC(=O)OC(C)(C)C)c2cccc(F)c21>>Cc1cc(C(=O)N2CCCCc3ccccc32)ccc1CNC(=O)N1CC(=O)N(CC(=O)O)c2cccc(F)c21 -US06376523B1,2,Cc1onc(N)c1Br.O=S(=O)(Cl)c1cccc2ccccc12>>Cc1onc(NS(=O)(=O)c2cccc3ccccc23)c1Br -US08309718B2,6,CC1(C)NC(=O)OC12CCN(C(=O)OCc1ccccc1)C2>>CC1(C)NC(=O)OC12CCNC2 -US20050070539A1,2,CCCCOC(=O)c1ccc(N2CCNCC2)cc1.O=C(O)c1cc([N+](=O)[O-])ccc1N1CCOCC1>>CCCCOC(=O)c1ccc(N2CCN(C(=O)c3cc([N+](=O)[O-])ccc3N3CCOCC3)CC2)cc1 -US20070219228A1,3,CCOCc1nc2c(N)nc3cc(Br)cnc3c2n1CC(C)C.OB(O)c1cccnc1>>CCOCc1nc2c(N)nc3cc(-c4cccnc4)cnc3c2n1CC(C)C -USRE045183E1,1,CCCS(=O)(=O)N1CCNCC1.O=Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1>>CCCS(=O)(=O)N1CCN(Cc2cnc(NC(=O)N(C3CCCCC3)C3CCCCC3)s2)CC1 -US20070232591A1,6,CC(C)(C)OC(=O)N1CCc2nc(Br)sc2C1>>Brc1nc2c(s1)CNCC2 -US20040186094A1,6,COc1ccc(-c2cc3c4c(c2)[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2N4CCSC3)c(C)c1>>COc1ccc(-c2cc3c4c(c2)[C@@H]2CNCC[C@@H]2N4CCSC3)c(C)c1 -US20140314669A1,2,CC(C)(C)OC(=O)N1CCC(CCC(=O)N2CCC[C@@H](C(=O)O)C2)CC1.COC(=O)CC(N)c1ccc(O)cc1>>COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1ccc(O)cc1 -US20060052408A1,6,CN(C[C@@]1(c2ccccc2)C[C@H]1COCc1ccccc1)C(=O)OC(C)(C)C>>CN(C[C@@]1(c2ccccc2)C[C@H]1CO)C(=O)OC(C)(C)C -US20110218189A1,6,C[Si](C)(C)C#Cc1c(Cl)cccc1Cl>>C#Cc1c(Cl)cccc1Cl -US20120004164A1,2,Cc1nc(-n2cnn(CCOc3ccc(F)cc3)c2=O)sc1C(=O)O.NCc1cccnc1>>Cc1nc(-n2cnn(CCOc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cccnc1 -US20070072847A1,6,COc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(Cc4ccccc4)CC3)CC2)cc(C)c1O>>COc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCNCC3)CC2)cc(C)c1O -US06495701B1,1,NCCOc1ccc2c(c1)[nH]c1ccccc12.O=Cc1ccccc1>>c1ccc(CNCCOc2ccc3c(c2)[nH]c2ccccc23)cc1 -US07666834B2,4,CC(C)C(=O)CBr.NC(=S)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>CC(C)c1csc(-c2ccc(C(F)(F)F)cc2[N+](=O)[O-])n1 -US20150018422A1,1,CCOC(=O)CC(c1ccnc(CO)c1)C1CC1.COc1ccc(F)c(-c2ccc(O)cc2CC(C)(C)C#N)c1>>CCOC(=O)CC(c1ccnc(COc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C#N)c2)c1)C1CC1 -US20120115869A1,2,CCCCC(=O)Cl.O=S(=O)(c1ccccc1)n1cccc1CNc1cc(-c2nnn[nH]2)ccc1F>>CCCCC(=O)N(Cc1cccn1S(=O)(=O)c1ccccc1)c1cc(-c2nnn[nH]2)ccc1F -US20050107616A1,2,CC(C)(C)[C@@H](O)Cc1nnc(-c2ccccc2)o1.CCCC[C@H](N=C=O)C(=O)OC>>CCCC[C@H](NC(=O)O[C@@H](Cc1nnc(-c2ccccc2)o1)C(C)(C)C)C(=O)OC -US20100121048A1,8,Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2CO)c(-c2ccccc2)n1-c1ccccc1>>Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2C=O)c(-c2ccccc2)n1-c1ccccc1 -US09079906B2,2,CC(C)(C)c1cc(OCCCOC2CCCCO2)cc(C(=O)O)c1.CNOC>>CON(C)C(=O)c1cc(OCCCOC2CCCCO2)cc(C(C)(C)C)c1 -US07622501B2,1,CCI.CS(=O)(=O)c1ccc(/C(COC(=O)OCCCC(CO[N+](=O)[O-])O[N+](=O)[O-])=C(/C(=O)O)c2ccccc2)cc1>>CCOC(=O)/C(=C(\COC(=O)OCCCC(CO[N+](=O)[O-])O[N+](=O)[O-])c1ccc(S(C)(=O)=O)cc1)c1ccccc1 -US20050075402A1,2,CCO.O=C(O)c1ccc(-c2ccc(O)cc2)cc1>>CCOC(=O)c1ccc(-c2ccc(O)cc2)cc1 -US20090264431A1,2,C[C@H]1C[C@@H](N)CN1C(=O)OC(C)(C)C.O=S(=O)(Cl)c1cc(Br)c(F)cc1F>>C[C@H]1C[C@@H](NS(=O)(=O)c2cc(Br)c(F)cc2F)CN1C(=O)OC(C)(C)C -US20070167449A1,9,Nc1ccc(OCCN2CCCC2)cc1.S=C(Cl)Cl>>S=C=Nc1ccc(OCCN2CCCC2)cc1 -US20100099695A1,1,C=CCc1ccccc1O.COC(=O)[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C>>C=CCc1ccccc1O[C@@H]1C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1 -US20060135573A1,7,COc1ccc2nc(-c3ccc4ccccc4c3)sc2c1[N+](=O)[O-]>>COc1ccc2nc(-c3ccc4ccccc4c3)sc2c1N -US20050267148A1,1,CCOC(=O)CCCBr.COc1ccc2c(c1)nc(S)n2Cc1csc2ccccc12>>CCOC(=O)CCCSc1nc2cc(OC)ccc2n1Cc1csc2ccccc12 -US09133148B2,3,Cc1cc(Br)ccc1CN1CCN(C(=O)OC(C)(C)C)CC1.Cc1cccc(B(O)O)c1>>Cc1cccc(-c2ccc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(C)c2)c1 -US05281614,2,CCC(=O)Br.CCCCc1nn(-c2cc(N)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1F>>CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1F -US20100298287A1,1,CCOC(=O)CCCn1c(Cl)nc2c(Cl)ccc(C(CC)CC)c21.Nc1cccc2c1OC(F)(F)O2>>CCOC(=O)CCCn1c(Nc2cccc3c2OC(F)(F)O3)nc2c(Cl)ccc(C(CC)CC)c21 -US20150018363A1,4,CNc1cc(-n2ccc(OCc3ccc(F)cc3)cc2=O)ccc1N.Cc1ncoc1C(=O)O>>Cc1ncoc1-c1nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc2n1C -US20150166483A1,6,COCCOCCOCCOCCOCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)OC(C)(C)C)c4ccccc34)n2)cc(OC)c1>>COCCOCCOCCOCCOCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(N)c4ccccc34)n2)cc(OC)c1 -US20150225367A1,1,CN1CCNCC1.O=S(=O)(c1ccccc1)n1cc(-c2ccc(Cl)nc2)c2ccc(F)cc21>>CN1CCN(c2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cn2)CC1 -US06610694B1,1,CCOC(=O)CBr.O=c1[nH]nc2ccc(OCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn12>>CCOC(=O)Cn1nc2ccc(OCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn2c1=O -US04652582,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)(=O)c1ccc(-c2[nH]ccc2-c2ccc(F)cc2)cc1>>CC(C)(C)OC(=O)n1ccc(-c2ccc(F)cc2)c1-c1ccc(S(C)(=O)=O)cc1 -US20100249129A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OC[C@@H]1CCCO1>>Cc1ccc(S(=O)(=O)OC[C@@H]2CCCO2)cc1 -US20140004041A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COC(=O)CC(=O)CC(=O)OC>>COC(=O)C=C(CC(=O)OC)CC(=O)OC -US20150045355A1,6,CCOC(=O)[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5c4CCC(=O)N5)cc3[C@H]21>>O=C1CCc2c(Oc3ccc4c(c3)[C@@H]3[C@H](O4)[C@H]3C(=O)O)ccnc2N1 -US20050239841A1,6,COc1ccc([C@@]23CC[C@@H](NC(=O)Nc4ccc(F)c(F)c4)C[C@@H]2N(Cc2ccccc2)CC3)cc1OC>>COc1ccc([C@]23CCN[C@H]2C[C@H](NC(=O)Nc2ccc(F)c(F)c2)CC3)cc1OC -US06013654,1,ClCc1cn2cc(Cl)ccc2n1.FC(F)(F)c1ccc(N2CCNCC2)nc1>>FC(F)(F)c1ccc(N2CCN(Cc3cn4cc(Cl)ccc4n3)CC2)nc1 -US05081237,7,C=CCOC(=O)N1CCC[C@H]1C(=O)OC>>C=CCOC(=O)N1CCC[C@H]1CO -US05194348,2,CCCCC(CC)COC(=O)Cl.CCCCCCCCCCCCCCCCOc1cccc(-c2cc(O)nn2-c2ccccc2)c1>>CCCCCCCCCCCCCCCCOc1cccc(-c2cc(OC(=O)OCC(CC)CCCC)nn2-c2ccccc2)c1 -US08178534B2,9,CCn1cc(-c2ccc(Cl)nc2)ccc1=O.NN>>CCn1cc(-c2ccc(NN)nc2)ccc1=O -US20140200227A1,6,C[C@H]1CN(C(=O)OCc2ccccc2)C[C@@H](NC(=O)OC(C)(C)C)[C@]1(C)O>>C[C@H]1CNC[C@@H](NC(=O)OC(C)(C)C)[C@]1(C)O -US20030207896A1,1,OCCCc1cnc(-c2ccccc2)c(-c2ccccc2)n1.Oc1ccc(Cn2ccnc2)cc1>>c1ccc(-c2ncc(CCCOc3ccc(Cn4ccnc4)cc3)nc2-c2ccccc2)cc1 -US20060004017A1,6,COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1OCc1ccccc1>>COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1O -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1.COc1ccc(OCCCCCCl)cc1OC>>COc1ccc(OCCCCCN2CCC(CNC(=O)c3cc(Cl)c(N)cc3OC)CC2)cc1OC -US20090318477A1,1,CC(C)(C)OC(=O)N1CCC(Oc2cccc3c2CCN3)CC1.Clc1ncc(Br)cn1>>CC(C)(C)OC(=O)N1CCC(Oc2cccc3c2CCN3c2ncc(Br)cn2)CC1 -US08987312B2,6,COC(=O)c1cccc(-c2noc(C(=O)CCCCCCc3ccccc3)n2)n1>>O=C(O)c1cccc(-c2noc(C(=O)CCCCCCc3ccccc3)n2)n1 -US20130210880A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2c(c1)CNC2=O>>COc1ccc2c(c1)CN(C(=O)OC(C)(C)C)C2=O -US20140296252A1,2,CC(C)(CO)C(=O)O.CO>>COC(=O)C(C)(C)CO -US06211234B1,7,COC(=O)CCC(C(=O)c1cccc(OCc2cccc([N+](=O)[O-])c2)c1)c1ccccc1C>>COC(=O)CCC(C(=O)c1cccc(OCc2cccc(N)c2)c1)c1ccccc1C -US20120196884A1,2,COc1cc(N)ccc1NC(=O)Nc1ccccc1.O=S(=O)(O)c1cccc(-c2ccc(F)cc2)c1>>COc1cc(NS(=O)(=O)c2cccc(-c3ccc(F)cc3)c2)ccc1NC(=O)Nc1ccccc1 -US20070010526A1,7,O=[N+]([O-])c1ccc(N2CCCCC2)cc1>>Nc1ccc(N2CCCCC2)cc1 -US20110280812A1,2,C#CC#CCC/C=C/C=C/C(=O)O.CCC(C)CN>>C#CC#CCC/C=C/C=C/C(=O)NCC(C)CC -US20140303222A1,9,CCCCc1nc(Br)c(C=O)n1Cc1ccc(C(=O)OC)c(F)c1F.NO>>CCCCc1nc(Br)c(C=NO)n1Cc1ccc(C(=O)OC)c(F)c1F -US20040092737A1,2,NCc1ccc2c(c1)Nc1nccnc1S2.O=C=Nc1ccccc1>>O=C(NCc1ccc2c(c1)Nc1nccnc1S2)Nc1ccccc1 -US06552054B1,2,Nc1ccc(CN2CCOCC2)cc1.O=C(O)c1cc(=O)c2c(O)c(O)ccc2o1>>O=C(Nc1ccc(CN2CCOCC2)cc1)c1cc(=O)c2c(O)c(O)ccc2o1 -US05308854,7,CSc1cc([N+](=O)[O-])c(=O)[nH]c1C>>CSc1cc(N)c(=O)[nH]c1C -US20040063720A1,1,N#Cc1cnc(Cl)s1.Nc1cc(N2CCCCC2)ncn1>>N#Cc1cnc(Nc2cc(N3CCCCC3)ncn2)s1 -US05482700,5,CCOC(=O)C(F)(F)F.N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O>>O=C(O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)C(F)(F)F -US08952169B2,2,NS(=O)(=O)N1CC(F)C1.O=C(O)c1cc(C2CC2)c(OCC2CCCCC2)cc1F>>O=C(NS(=O)(=O)N1CC(F)C1)c1cc(C2CC2)c(OCC2CCCCC2)cc1F -US05362738,2,C[C@H]1CNC[C@@H](C)O1.O=C(O)c1cc(-c2ccccc2)c(=O)n2c1-c1ccccc1C2>>C[C@H]1CN(C(=O)c2cc(-c3ccccc3)c(=O)n3c2-c2ccccc2C3)C[C@@H](C)O1 -US20120129854A1,6,CC(C)(C)OC(=O)Nc1cccc2cc(N3CCC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)ccc12>>Nc1cccc2cc(N3CCC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)ccc12 -US20130040930A1,1,N#Cc1cc(Br)ccc1C(=O)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1.O=C1CCCN1>>N#Cc1cc(N2CCCC2=O)ccc1C(=O)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1 -US20150265612A1,2,Cc1cnc(N)nc1-c1cccc(C(=O)OC(C)(C)C)c1.O=C(Cl)C1(c2ccc3c(c2)OC(F)(F)O3)CC1>>Cc1cnc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1cccc(C(=O)OC(C)(C)C)c1 -US06897224B2,1,COC(=O)c1ccc2c(N)cccc2n1.COc1ccc(F)cc1C(C)(C)CC(O)(C=O)C(F)(F)F>>COC(=O)c1ccc2c(N=CC(O)(CC(C)(C)c3cc(F)ccc3OC)C(F)(F)F)cccc2n1 -US04535090,2,CCCCCCCC(=O)Cl.CCOc1cccc(-c2n[nH]c(-c3ccccc3CO)n2)c1>>CCCCCCCC(=O)OCc1ccccc1-c1nc(-c2cccc(OCC)c2)n[nH]1 -US20060276504A1,2,CCC[C@H]1CC[C@@H](CCC)N1.COc1ccc2oc(C(=O)C(C)(C)C)c(CC(=O)O)c2c1>>CCC[C@H]1CC[C@@H](CCC)N1C(=O)Cc1c(C(=O)C(C)(C)C)oc2ccc(OC)cc12 -US20080269286A1,7,Fc1ccc(C2=CCNCC2)cc1Cl>>Fc1ccc(C2CCNCC2)cc1Cl -US20100210628A1,1,Clc1ncnc(Cl)n1.O=C(NCc1ccccc1C(F)(F)F)C1CCNCC1>>O=C(NCc1ccccc1C(F)(F)F)C1CCN(c2ncnc(Cl)n2)CC1 -US20080255057A1,3,CCI.COc1ccc(-c2nc3cc(OC)cc(Br)c3o2)cc1>>CCc1cc(OC)cc2nc(-c3ccc(OC)cc3)oc12 -US05120748,1,ClCCCBr.Sc1ccncc1>>ClCCCSc1ccncc1 -US05849945,7,Cc1cc(C(=O)CCC(=O)O)ccc1F>>Cc1cc(CCCC(=O)O)ccc1F -US20040180925A1,1,C1CC2(CCN1)OCCO2.N#Cc1cccnc1Cl>>N#Cc1cccnc1N1CCC2(CC1)OCCO2 -US04067903,1,CCCCO.Cc1cccc(N)c1>>CCCCNc1cccc(C)c1 -US20070213355A1,1,Brc1ccc(Br)nc1.C1COCCN1>>Brc1ccc(N2CCOCC2)nc1 -US20090318412A1,6,COc1cccc2c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1CO2>>COc1cccc2c1C(=O)N1CCNCC1CO2 -US07521461B2,6,COC(=O)c1ccccc1COc1cccc(CCOc2ccc(OS(C)(=O)=O)cc2)c1>>CS(=O)(=O)Oc1ccc(OCCc2cccc(OCc3ccccc3C(=O)O)c2)cc1 -US20140107109A1,9,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(Br)ccc2F)CS(=O)(=O)C1(C)C.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N=[N+]=[N-])ccc2F)CS(=O)(=O)C1(C)C -US05739336,2,CNOC.COc1ccc(Cl)cc1C(=O)O>>COc1ccc(Cl)cc1C(=O)N(C)OC -US20090298807A1,6,CC(C)(C)OC(=O)N(Cc1ccc(OCCN2CCC3(CC2)CN(C(=O)C(F)(F)F)CCO3)cc1)C[C@H](O)c1ccc(O)c2[nH]c(=O)sc12>>CC(C)(C)OC(=O)N(Cc1ccc(OCCN2CCC3(CC2)CNCCO3)cc1)C[C@H](O)c1ccc(O)c2[nH]c(=O)sc12 -US20080108595A1,6,COC(=O)[C@@H](O)CSCc1ccccc1>>O=C(O)[C@@H](O)CSCc1ccccc1 -US06642231B2,9,NO.O=C1CCN(CCCO)CC1>>OCCCN1CCC(=NO)CC1 -US20040158066A1,1,Cc1nc(C)c(Cl)c(N)n1.ClCc1ccc(OCc2ccccc2)c(Cl)n1>>Cc1nc(C)c(Cl)c(NCc2ccc(OCc3ccccc3)c(Cl)n2)n1 -US20140194431A1,2,CC(C)NCCO[Si](C)(C)C(C)(C)C.O=C(O)c1nc(CC2(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CCCC2)nc(O)c1OCc1ccccc1>>CC(C)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1nc(CC2(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CCCC2)nc(O)c1OCc1ccccc1 -US08329687B2,7,O=C1c2ccc(Oc3ccccc3)nc2OCCN1Cc1ccccc1>>c1ccc(CN2CCOc3nc(Oc4ccccc4)ccc3C2)cc1 -US06743817B2,1,CN.O=[N+]([O-])c1ccc(OCCCl)cc1>>CNCCOc1ccc([N+](=O)[O-])cc1 -US06444668B1,3,O=C1Nc2ccc(Br)cc2C2(CCCCC2)O1.O=[N+]([O-])c1cccc(B(O)O)c1>>O=C1Nc2ccc(-c3cccc([N+](=O)[O-])c3)cc2C2(CCCCC2)O1 -US08299023B2,7,CC(C)(C)OCC(NC(=O)c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-])C(=O)OC(C)(C)C>>CC(C)(C)OCC(NC(=O)c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N)C(=O)OC(C)(C)C -US05446062,7,CC(=O)N(C)c1ccc(C(=O)O)cc1>>CC(=O)N(C)c1ccc(CO)cc1 -US20110319378A1,4,N#CC[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O.[N-]=[N+]=[N-]>>O=C1[C@@H](Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1 -US08426359B2,6,CCOC(=O)C(=O)Nc1ccccc1>>O=C(O)C(=O)Nc1ccccc1 -US07446222B2,4,N#Cc1cccc(-c2ccccc2Br)c1.[N-]=[N+]=[N-]>>Brc1ccccc1-c1cccc(-c2nnn[nH]2)c1 -US07572934B2,6,C/C=C/[C@H](CC(=O)OCC)c1ccc(OC)cc1C>>C/C=C/[C@H](CC(=O)OCC)c1ccc(O)cc1C -US20150266870A1,2,C1COCCN1.Nc1ccc(C(=O)O)cn1>>Nc1ccc(C(=O)N2CCOCC2)cn1 -US20150210681A1,3,C#CC(C)(C)NC(=O)OC(C)(C)C.COCCc1ccc(Br)cc1>>COCCc1ccc(C#CC(C)(C)NC(=O)OC(C)(C)C)cc1 -US20140073620A1,3,C#Cc1ccccc1C1(C(N)=O)CC1.CC(C)(C)OC(=O)N1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(Cl)n3)cn2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(C#Cc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1 -US20110190263A1,6,CCc1cnc(N2CCC(COC3CN(C(=O)OC(C)(C)C)C3)CC2)nc1>>CCc1cnc(N2CCC(COC3CNC3)CC2)nc1 -US04420435,9,CC(=O)[C@H]1[C@H](C(=O)O)C1(C)C>>CC(=O)[C@H]1[C@H](C=O)C1(C)C -US20150166480A1,3,CC(C)(F)CN1CCC(COc2cnc(I)cn2)CC1.CCOC(=O)c1ccc(B(O)O)cc1F>>CCOC(=O)c1ccc(-c2cnc(OCC3CCN(CC(C)(C)F)CC3)cn2)cc1F -US20090298878A1,6,COC(=O)c1cccc(CON=C2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)c1>>O=C(O)c1cccc(CON=C2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)c1 -US06743792B2,2,CC(C(=O)Cl)(c1ccc(Cl)cc1)c1ccc(-n2ncc(=O)[nH]c2=O)cc1Cl.CN>>CNC(=O)C(C)(c1ccc(Cl)cc1)c1ccc(-n2ncc(=O)[nH]c2=O)cc1Cl -US20130331382A1,1,BrCc1ccccn1.COc1cc(=O)n(C)nc1-c1ccccc1O>>COc1cc(=O)n(C)nc1-c1ccccc1OCc1ccccn1 -US20070142428A1,6,COC(=O)c1cc2cc(F)ccc2cn1>>O=C(O)c1cc2cc(F)ccc2cn1 -US04557867,8,C[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2[C@H](O)C[C@]3(C)C(=O)CC[C@H]3[C@@H]21>>C[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2C(=O)C[C@]3(C)C(=O)CC[C@H]3[C@@H]21 -US05780501,9,Clc1cccc(Oc2ccccc2)c1CBr.[C-]#N>>N#CCc1c(Cl)cccc1Oc1ccccc1 -US04423056,2,CCCCc1nc2c(s1)CCC(CO)C2.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCCc1nc2c(s1)CCC(COS(=O)(=O)c1ccc(C)cc1)C2 -US20060189621A1,1,CN1CCNCC1.CS(=O)(=O)OCc1cc(-c2ccc3c(c2)CCO3)nn(CC2CC2)c1=O>>CN1CCN(Cc2cc(-c3ccc4c(c3)CCO4)nn(CC3CC3)c2=O)CC1 -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(F)c(F)c4)cc3)cc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(F)c(F)c4)cc3)cc2C1=O -US03988448,1,N#CCCl.c1ccc(C2(c3ccccc3)CCNCCO2)cc1>>N#CCN1CCOC(c2ccccc2)(c2ccccc2)CC1 -US20090247567A1,2,CNc1ccccc1Cl.Cc1ccc2c(c1)-c1sc(C(=O)O)cc1CO2>>Cc1ccc2c(c1)-c1sc(C(=O)N(C)c3ccccc3Cl)cc1CO2 -US06835735B2,1,COCC1COc2cc3ncnc(Cl)c3cc2O1.Cc1cc(C)cc(N)c1>>COCC1COc2cc3ncnc(Nc4cc(C)cc(C)c4)c3cc2O1 -US20030216462A1,2,Cc1cc(C)c(C(C(=O)O)=C2C(=O)Nc3ccccc32)[nH]1.Nc1ccccc1Cl>>Cc1cc(C)c(C(C(=O)Nc2ccccc2Cl)=C2C(=O)Nc3ccccc32)[nH]1 -US08552205B2,6,CC(C)(C)OC(=O)NNC1(NC(=S)OCc2ccccc2)CC1>>NNC1(NC(=S)OCc2ccccc2)CC1 -US20110105758A1,7,CC(C)(C)OC(=O)N1CC(C(=O)O)=C(c2cccc(F)c2)C1>>CC(C)(C)OC(=O)N1CC(C(=O)O)C(c2cccc(F)c2)C1 -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(Oc3cnccn3)cc(C)c21>>Cc1cc(Oc2cnccn2)cc2c1C(CC(=O)O)OB2O -US04699905,1,CC(C)(C)OC(=O)CN1CC(c2cccs2)SCC(N)C1=O.O=C(OCc1ccccc1)C(Br)CCc1ccccc1>>CC(C)(C)OC(=O)CN1CC(c2cccs2)SCC(NC(CCc2ccccc2)C(=O)OCc2ccccc2)C1=O -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C1CCOCC1>>CN(C(=O)N(C)[C@@H]1CN(C(=O)C2CCOCC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US06271234B1,2,COc1cc(N)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1.O=CO>>COc1cc(NC=O)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 -US20100029722A1,6,CCOC(=O)c1nnn(-c2nc(C)c(C(=O)NCc3ccccc3)s2)c1C>>Cc1nc(-n2nnc(C(=O)O)c2C)sc1C(=O)NCc1ccccc1 -US20080306085A1,1,ClCCCN1CCCCC1.c1c[nH]c(-c2ccc(OCCCN3CCCCC3)cc2)c1>>c1cc(-c2ccc(OCCCN3CCCCC3)cc2)n(CCCN2CCCCC2)c1 -US20040058978A1,2,CC(=O)O.CN(C(=O)CN)c1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1>>CC(=O)NCC(=O)N(C)c1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1 -US20080200423A1,7,C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cc2ccc3c(=O)[nH]ncc(n1)c23>>C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1N1C=C2CCC3=C2C(=N1)C=NNC3=O -US20120022058A1,3,COC(=O)c1ccc(B(O)O)cc1.Cc1nc(N2N=C(Cl)C[C@@H]2C2CCCC2)ccc1C#N>>COC(=O)c1ccc(C2=NN(c3ccc(C#N)c(C)n3)[C@@H](C3CCCC3)C2)cc1 -US20090124598A1,2,CNCc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1.O=C=NC(=O)c1ccccc1>>CN(Cc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1)C(=O)NC(=O)c1ccccc1 -US06509337B1,2,CC(C)(C)OC(=O)CN.COc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(S(=O)(=O)NCC(=O)OC(C)(C)C)cc1 -US20080221097A1,1,CCOC(=O)c1cnc(Cl)c2ncn(C)c12.Nc1cccc(Cl)c1>>CCOC(=O)c1cnc(Nc2cccc(Cl)c2)c2ncn(C)c12 -US07491748B2,9,CC(C)CC(NC(=O)c1cc(COc2ccccc2)ccc1CCC(N)=O)c1ccc(F)cc1>>CC(C)CC(NC(=O)c1cc(COc2ccccc2)ccc1CCC#N)c1ccc(F)cc1 -US08519134B2,9,N.O=C(O)c1ccc2cc(Br)ccc2c1>>NC(=O)c1ccc2cc(Br)ccc2c1 -US08450319B2,3,CCOC(=O)c1c(B2OC(C)(C)C(C)(C)O2)cn(COCc2ccccc2)c1C=O.Fc1ccccc1CBr>>CCOC(=O)c1c(Cc2ccccc2F)cn(COCc2ccccc2)c1C=O -US07863332B2,2,CCCCCCCCN=C=O.CCOC(=O)CCc1ccc(-c2cccc(NC)c2)cc1>>CCCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OCC)cc2)c1 -US09139576B2,2,CCOC(=O)CN(Cc1ccc(-c2ccc3c(nnn3CC3CC3)c2C(F)(F)F)cc1)C(N)=O>>O=C1CN(Cc2ccc(-c3ccc4c(nnn4CC4CC4)c3C(F)(F)F)cc2)C(=O)N1 -US06018046,6,CCOC(=O)COc1cc2c(=O)c(Cc3cccnc3)cn3c4ccc(Br)cc4c(c1)c23>>O=C(O)COc1cc2c(=O)c(Cc3cccnc3)cn3c4ccc(Br)cc4c(c1)c23 -US07326791B2,2,CC(NC(=O)c1ccc(C(=O)O)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1.c1cc2c(s1)CCNC2>>CC(NC(=O)c1ccc(C(=O)N2CCc3sccc3C2)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1 -US08063077B2,1,O=C(NCc1cn(-c2ccc(I)cc2)cn1)c1ccc(Cl)s1.O=C1NCCCN1>>O=C(NCc1cn(-c2ccc(N3CCCNC3=O)cc2)cn1)c1ccc(Cl)s1 -US20140142097A1,3,CC(C)(C)OC(=O)Nc1ccccc1B1OC(C)(C)C(C)(C)O1.Nc1ncc(Br)cc1C(=O)Nc1ccncc1>>CC(C)(C)OC(=O)Nc1ccccc1-c1cnc(N)c(C(=O)Nc2ccncc2)c1 -US05254575,1,ClCCN1CCCCC1.N#Cc1nc(-c2ccc(O)cc2)cs1>>N#Cc1nc(-c2ccc(OCCN3CCCCC3)cc2)cs1 -US04959372,1,CC(C)(C)OC(=O)[C@@H](N)CCCCNC(=O)OCc1ccccc1.CCOC(=O)C(=O)CCc1ccccc1>>CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C -US20150031674A1,7,CCOC(=O)C(C)OC1CN(C(=O)OC(C)(C)C)C1>>CC(CO)OC1CN(C(=O)OC(C)(C)C)C1 -US07332498B2,6,Cc1ccc(C(=O)N(CCCN2C(=O)c3ccccc3C2=O)C(c2nc3ccncc3c(=O)n2Cc2ccccc2)C(C)C)cc1>>Cc1ccc(C(=O)N(CCCN)[C@@H](c2nc3ccncc3c(=O)n2Cc2ccccc2)C(C)C)cc1 -US07332498B2,6,Cc1ccc(C(=O)N(CCCN2C(=O)c3ccccc3C2=O)C(c2nc3ccncc3c(=O)n2Cc2ccccc2)C(C)C)cc1>>Cc1ccc(C(=O)N(CCCN)C(c2nc3ccncc3c(=O)n2Cc2ccccc2)C(C)C)cc1 -US20140213577A1,1,CC(=CBr)c1cccc(F)c1.Cc1ccc2[nH]c3c(c2c1)CCN(C)CC3>>C/C(=C/n1c2c(c3cc(C)ccc31)CCN(C)CC2)c1cccc(F)c1 -US20080181866A1,6,CC(C)(C)OC(=O)N1CCCC([C@H]2SCC(C(=O)O)N2C(=O)OCc2ccccc2)C1>>O=C(O)C1CS[C@H](C2CCCNC2)N1C(=O)OCc1ccccc1 -US08173631B2,7,Cc1ccc(C(=O)[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1F>>Cc1ccc(C(O)[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1F -US07196099B2,2,NC1CCCN(C(=O)OCc2ccccc2)CC1O.O=C(O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1>>O=C(NC1CCCN(C(=O)OCc2ccccc2)CC1O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1 -US20100168175A1,6,COC(=O)c1c(O)c(OC)c(OC)n(Cc2ccc(OC)cc2)c1=O>>COc1ccc(Cn2c(OC)c(OC)c(O)c(C(=O)O)c2=O)cc1 -US20080153813A1,1,CCOCc1cnc2ccc(Cl)nn12.NCc1ccccn1>>CCOCc1cnc2ccc(NCc3ccccn3)nn12 -US20010014694A1,6,CCOC(=O)c1c(Oc2ccc(OC)cc2)cccc1Oc1ccc2c(c1)OCO2>>COc1ccc(Oc2cccc(Oc3ccc4c(c3)OCO4)c2C(=O)O)cc1 -US07012089B2,9,BrC(Br)(Br)Br.O=[N+]([O-])c1cccc(Cl)c1CCO>>O=[N+]([O-])c1cccc(Cl)c1CCBr -US06855722B2,1,CC(C)(C)OC(=O)N1CCCc2ccc(CCO)nc21.CCCC(CC(=O)OCC)n1ccc2cc(O)ccc21>>CCCC(CC(=O)OCC)n1ccc2cc(OCCc3ccc4c(n3)N(C(=O)OC(C)(C)C)CCC4)ccc21 -US20090111862A1,7,COc1cc(C(=O)OCc2ccccc2)cc(Cl)c1OCc1ccccc1>>COc1cc(CO)cc(Cl)c1OCc1ccccc1 -US20070129288A1,2,CC(C)(C)OC(=O)NC[C@H](O)C[C@@H]1NC(=O)[C@@H](NC(=O)OC(C)(C)C)Cc2cc(ccc2O)-c2ccc(O)c(c2)C[C@@H](C(=O)O)NC1=O.NCc1ccccc1>>CC(C)(C)OC(=O)NC[C@H](O)C[C@@H]1NC(=O)[C@@H](NC(=O)OC(C)(C)C)Cc2cc(ccc2O)-c2ccc(O)c(c2)C[C@@H](C(=O)NCc2ccccc2)NC1=O -US06310238B1,1,O=C(OCc1ccccc1)c1ccc(Oc2nc(F)c(F)c(F)c2F)cc1.O=[N+]([O-])c1ccc([O-])cc1OCc1ccccc1>>O=C(OCc1ccccc1)c1ccc(Oc2nc(F)c(F)c(Oc3ccc([N+](=O)[O-])c(OCc4ccccc4)c3)c2F)cc1 -US20150111914A1,6,COC(=O)c1ccc2c(c1)C(F)(F)C1(C2)C(=O)Nc2ncccc21>>O=C(O)c1ccc2c(c1)C(F)(F)C1(C2)C(=O)Nc2ncccc21 -US20150119393A1,2,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4cc(Cl)c(-c5ccc([C@@H]6CC[C@H](O)CC6)cc5)nc4n3COCC[Si](C)(C)C)CO[C@H]12.CC(C)N=C=O>>CC(C)NC(=O)O[C@H]1CC[C@@H](c2ccc(-c3nc4c(cc3Cl)nc(O[C@@H]3CO[C@@H]5[C@H](O[Si](C)(C)C(C)(C)C)CO[C@H]35)n4COCC[Si](C)(C)C)cc2)CC1 -US20080103302A1,2,CCOC(=O)Cl.COC(=O)C(=Cc1cc(OC)cc(OC)c1)c1ccc(Oc2ccc(CCC(N)=O)cc2)cc1>>CCOC(=O)NC(=O)CCc1ccc(Oc2ccc(C(=Cc3cc(OC)cc(OC)c3)C(=O)OC)cc2)cc1 -US05317018,9,N.O=C(O)c1ncn2c1CN=C(c1ccccc1Br)c1cc(F)ccc1-2>>NC(=O)c1ncn2c1CN=C(c1ccccc1Br)c1cc(F)ccc1-2 -US20140336106A1,2,COc1ccc(C[C@H](NC(=O)[C@H](C)N)C(=O)OCc2ccccc2)cc1.O=C(O)CN1CCC(O)CC1>>COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCC(O)CC2)C(=O)OCc2ccccc2)cc1 -US05527819,9,NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1>>N#Cc1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1 -US05693809,2,CC(C)(C)C(=O)Cl.CC(O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C>>CC(OC(=O)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C -US04665179,7,NCCc1c(N)cc([N+](=O)[O-])cc1S(=O)(=O)Cc1ccccc1>>NCCc1c(N)cc(N)cc1S(=O)(=O)Cc1ccccc1 -US06441173B1,1,CCCI.O=Cc1cccc(O)c1>>CCCOc1cccc(C=O)c1 -US04015007,2,C1CNCC2(C1)CC1CCC2CC1.O=C(Cl)CCCl>>O=C(CCCl)N1CCCC2(CC3CCC2CC3)C1 -US05712300,2,C=C(C)C1(C(CCN)C(=O)OC(C)(C)C)CCN(CCc2ccccc2)C1=O.O=C(Cl)c1ccc(F)c(F)c1>>C=C(C)C1(C(CCNC(=O)c2ccc(F)c(F)c2)C(=O)OC(C)(C)C)CCN(CCc2ccccc2)C1=O -US07192722B2,1,CC(C)(C)OC(=O)COc1ccc(CC=O)cc1.CC(N)C(O)c1ccc(O)cc1>>CC(NCCc1ccc(OCC(=O)OC(C)(C)C)cc1)C(O)c1ccc(O)cc1 -US20140323537A1,6,CC(C)Oc1ccc(-c2nn(C)cc2CN(C)CCN(C)Cc2ccccc2)cc1>>CNCCN(C)Cc1cn(C)nc1-c1ccc(OC(C)C)cc1 -US08088760B2,9,CNCc1ccc(-c2nc3cccc(C(=O)OC)c3o2)cc1.[NH4+]>>CNCc1ccc(-c2nc3cccc(C(N)=O)c3o2)cc1 -US20090105219A1,6,O=C1CC2(CN3C(=O)c4ccccc4C3=O)C(=O)Nc3cccc(c32)N1>>NCC12CC(=O)Nc3cccc(c31)NC2=O -US07348341B2,2,NCCN1CCC(Oc2ccc(F)c(F)c2)CC1.O=S(=O)(Cl)c1ccc(-c2ccccn2)s1>>O=S(=O)(NCCN1CCC(Oc2ccc(F)c(F)c2)CC1)c1ccc(-c2ccccn2)s1 -US20110257174A1,7,O=c1cc(-c2cccc(C(F)(F)F)c2)oc2c([N+](=O)[O-])cccc12>>Nc1cccc2c(=O)cc(-c3cccc(C(F)(F)F)c3)oc12 -US20140179669A1,6,CCOC(=O)c1cccc2c1C[C@H]1N(Cc3ccccc3)CC[C@]2(C)C1(C)C>>CCOC(=O)c1cccc2c1C[C@H]1NCC[C@]2(C)C1(C)C -US05814634,6,COC(=O)c1ccc(OC/C=C(\C)CCC=C(C)C)cc1>>CC(C)=CCC/C(C)=C/COc1ccc(C(=O)O)cc1 -US08481725B2,2,NC1(C(=O)OCc2ccccc2)CCCCC1.O=C(Cl)N1CCNC1=O>>O=C1NCCN1C(=O)NC1(C(=O)OCc2ccccc2)CCCCC1 -US07049441B2,1,Cc1ccc(N)cc1Cl.ClCCCBr>>Cc1ccc(NCCCCl)cc1Cl -US20120258946A1,2,CC(CO)(CO)c1ccc(N)cc1F.O=C(Cl)Oc1ccccc1>>CC(CO)(CO)c1ccc(NC(=O)Oc2ccccc2)cc1F -US20090131414A1,3,NC(=O)c1nc(Cl)ccc1N.OB(O)c1ccc(F)cc1>>NC(=O)c1nc(-c2ccc(F)cc2)ccc1N -US20090286778A1,2,Cc1cc(C(=O)Cl)no1.Nc1cc2cc(c1)Nc1nc(ncc1Cl)Nc1cccc(c1)CC2>>Cc1cc(C(=O)Nc2cc3cc(c2)Nc2nc(ncc2Cl)Nc2cccc(c2)CC3)no1 -US20020103203A1,6,CC(=O)Oc1ccc(C(=O)Nc2cccc(OCc3cncc4ccccc34)c2)cc1C(C)(C)C>>CC(C)(C)c1cc(C(=O)Nc2cccc(OCc3cncc4ccccc34)c2)ccc1O -US20090226398A1,1,Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F.O=C(Nc1ccccc1)c1ccc(CCl)cc1>>O=C(Nc1ccccc1)c1ccc(Cn2cc3nc(-c4cccc(F)c4F)nc-3cn2)cc1 -US08063240B2,7,O=C1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2CCC(F)(F)COc2ccccc2)O1>>OC1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2CCC(F)(F)COc2ccccc2)O1 -US06743939B2,7,Cn1ccnc1C(=O)CCCNC(=O)OC(C)(C)C>>Cn1ccnc1[C@H](O)CCCNC(=O)OC(C)(C)C -US20120101136A1,1,CC(C)Oc1ccc(-c2nc(-c3ccc(O)cc3Cl)no2)cc1C#N.CCOC(=O)CCCBr>>CCOC(=O)CCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c(Cl)c1 -US07517875B2,2,COC(=O)c1ccc(NC(=O)OC(C)(C)C)c(N)c1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>COC(=O)c1ccc(NC(=O)OC(C)(C)C)c(NS(=O)(=O)c2ccccc2[N+](=O)[O-])c1 -US20130310394A1,2,Cc1ccoc1C(=O)O.Nc1cccc(C2CN=C3c4ccccc4NC(=O)N3C2)c1>>Cc1ccoc1C(=O)Nc1cccc(C2CN=C3c4ccccc4NC(=O)N3C2)c1 -US03965180,9,COC1(c2ccc(C)cc2)CCC(=O)CC1.NO>>COC1(c2ccc(C)cc2)CCC(=NO)CC1 -US20090318690A1,1,CN(C)Cc1c(-c2ccccc2)ccc2c(CCC3CCNCC3)noc12.O=Cc1cccs1>>CN(C)Cc1c(-c2ccccc2)ccc2c(CCC3CCN(Cc4cccs4)CC3)noc12 -US06500853B1,3,O=C(O)Cc1cn(Cc2ccccc2)c2ccc(Br)cc12.OB(O)c1cc2ccccc2o1>>O=C(O)Cc1cn(Cc2ccccc2)c2ccc(-c3cc4ccccc4o3)cc12 -US20060063779A1,2,CN.Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2ccc(C(=O)[O-])cn2)c1>>CNC(=O)c1ccc(-c2cc(NC(=O)c3ccc(C(F)(F)F)nc3C)ccc2Cl)nc1 -US07115619B2,3,C=CC(=O)N1CCOCC1.CC(=O)OCCCc1cc2c3c(nc4ccc(Cl)cc4c3c1)-c1ccccc1N2C>>CC(=O)OCCCc1cc2c3c(nc4ccc(/C=C/C(=O)N5CCOCC5)cc4c3c1)-c1ccccc1N2C -US20140274703A1,1,CI.Oc1c(Br)ccc(Cl)c1F>>COc1c(Br)ccc(Cl)c1F -US08722934B2,9,CCCCCCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCOc1ccc(C(N=[N+]=[N-])c2ccc(OCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCCCCCC)cc2)cc1>>CCCCCCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCOc1ccc(C(N)c2ccc(OCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCCCCCC)cc2)cc1 -US04992459,1,COC(CN)OC.COc1ccc(C=O)cc1F>>COc1ccc(CNCC(OC)OC)cc1F -US06759414B2,2,Nc1ccc(Cl)nc1.O=C(Cl)c1ccccc1[N+](=O)[O-]>>O=C(Nc1ccc(Cl)nc1)c1ccccc1[N+](=O)[O-] -US20150166512A1,3,CCB(O)O.COC(=O)c1cc(Cl)ccc1Br>>CCc1ccc(Cl)cc1C(=O)OC -US06884868B1,1,CC(=O)N1CCN(c2ccc(OS(=O)(=O)C(F)(F)F)cc2)CC1.COC1(c2ccccc2)CCNCC1>>COC1(c2ccccc2)CCN(c2ccc(N3CCN(C(C)=O)CC3)cc2)CC1 -US04173478,2,COc1ccc(N=Nc2ccc(O)c(C(=O)Cl)c2)cc1.NCc1nnn[nH]1>>COc1ccc(N=Nc2ccc(O)c(C(=O)NCc3nnn[nH]3)c2)cc1 -US20040048868A1,2,CN1CCN(C(=O)Cl)CC1.Nc1cn(C2CCCCO2)nc1-c1nc2cc3c(cc2[nH]1)CCC3>>CN1CCN(C(=O)Nc2cn(C3CCCCO3)nc2-c2nc3cc4c(cc3[nH]2)CCC4)CC1 -US20150111866A1,2,CS(=O)(=O)Cl.OCc1cc(Cl)ncc1Br>>CS(=O)(=O)OCc1cc(Cl)ncc1Br -US05998666,1,NC(=O)Nc1cccc(O)c1.O=C(CCCCN(CCCl)Cc1ccccc1)NC1CCCCCC1>>NC(=O)Nc1cccc(OCCN(CCCCC(=O)NC2CCCCCC2)Cc2ccccc2)c1 -US20070225349A1,1,CCCI.COc1ccc(-c2n[nH]c3c(C(F)(F)F)cccc23)cc1>>CCCn1nc(-c2ccc(OC)cc2)c2cccc(C(F)(F)F)c21 -US09150510B2,2,COC(=O)[C@@H](N)CC(C)C.O=C(O)C=Cc1ccccc1F>>COC(=O)[C@H](CC(C)C)NC(=O)C=Cc1ccccc1F -US20090247526A1,1,Cc1csc(N)n1.Clc1cc(Oc2ccccc2Cl)ccn1>>Cc1csc(Nc2cc(Oc3ccccc3Cl)ccn2)n1 -US04128548,7,COc1ccc2c(c1)C(=CCO)C(C)(C)C(N(C)S(=O)(=O)c1ccc(C)cc1)C2>>COc1ccc2c(c1)C(CCO)C(C)(C)C(N(C)S(=O)(=O)c1ccc(C)cc1)C2 -US20130131075A1,7,COC(=O)c1ccc(Nc2ccc(C#N)nc2)c(C(F)(F)F)c1>>COC(=O)c1ccc(Nc2ccc(CN)nc2)c(C(F)(F)F)c1 -US20040138462A1,1,CCI.O=S(=O)(c1ccc(O)cc1)c1ccc(CCN(Cc2ccccc2)C[C@H](O)c2cccc(Cl)c2)cc1>>CCOc1ccc(S(=O)(=O)c2ccc(CCN(Cc3ccccc3)C[C@H](O)c3cccc(Cl)c3)cc2)cc1 -US20040097499A1,2,CC(CN)c1ccc(-c2ccsc2)cc1.O=C(Cl)N1CCOCC1>>CC(CNC(=O)N1CCOCC1)c1ccc(-c2ccsc2)cc1 -US20150094328A1,1,C=O.O=C(N[C@H]1CCCNC1)c1cn(Cc2ccc(-n3cccn3)cc2)c2cccnc12>>CN1CCC[C@H](NC(=O)c2cn(Cc3ccc(-n4cccn4)cc3)c3cccnc23)C1 -US08389514B2,9,C[C@H]1COc2c(F)c(F)c(N)c3c(=O)c(C(N)=O)cn1c23>>C[C@H]1COc2c(F)c(F)c(N)c3c(=O)c(C#N)cn1c23 -US07622502B2,7,CC(=O)OCCCC(CO[N+](=O)[O-])O[N+](=O)[O-]>>O=[N+]([O-])OCC(CCCO)O[N+](=O)[O-] -US07235548B2,1,CO.FC(F)(F)c1ccc(Br)cc1>>COc1ccc(C(F)(F)F)cc1 -US20040220191A1,3,C#Cc1ccc(OCCCC)cc1.CN(C)C1CCN(c2ccc(NC(=O)c3ccc(Br)o3)cc2)C1>>CCCCOc1ccc(C#Cc2ccc(C(=O)Nc3ccc(N4CCC(N(C)C)C4)cc3)o2)cc1 -US20120157448A1,3,CC1(C)OB(c2cncc(C#N)c2)OC1(C)C.NC1=NC2(CO1)c1cc(Br)ccc1O[C@H]1CCC(=O)C[C@@H]12>>N#Cc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)[C@H]2CC(=O)CC[C@@H]2O3)c1 -US08148383B2,1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)[nH]c2ncnn12.COc1ccc(B(O)O)cc1F>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(OC)c(F)c2)c2ncnn12 -US20080221097A1,1,CCOC(=O)c1cnc(Cl)c2ncn(C)c12.Nc1cccc(Br)c1>>CCOC(=O)c1cnc(Nc2cccc(Br)c2)c2ncn(C)c12 -US20090149514A1,1,NN.O=Cc1ccccc1>>NN=Cc1ccccc1 -US05338857,8,CCC(O)c1cc(-c2ccccc2)no1>>CCC(=O)c1cc(-c2ccccc2)no1 -US06107458,6,CCCCCc1ccc(-c2ccc(C=CC(=O)OC)cc2)cc1>>CCCCCc1ccc(-c2ccc(C=CC(=O)O)cc2)cc1 -US06841549B1,1,COc1ccc(N)cn1.O=[N+]([O-])c1cccnc1Cl>>COc1ccc(Nc2ncccc2[N+](=O)[O-])cn1 -US20150150879A2,2,CN.CN(C)C(=O)c1ccc(-c2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2C(=O)O)cc1>>CNC(=O)c1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)cc1-c1ccc(C(=O)N(C)C)cc1 -US07001917B2,4,CC(=O)C(Cc1ccccc1)C(C)=O.NNc1ccc(CCO)cc1>>Cc1nn(-c2ccc(CCO)cc2)c(C)c1Cc1ccccc1 -US20040220234A1,9,OC(CCI)C(F)(F)F.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCC(O)C(F)(F)F -US20130096118A1,7,Cc1c(C#N)cccc1[N+](=O)[O-]>>Cc1c(N)cccc1C#N -US05463077,2,COc1ccccc1C1(O)C(O)CC(c2ccccc2)(c2ccccc2)C2CNCC21.O=C(O)Cc1c[nH]c2ccccc12>>COc1ccccc1C1(O)C(O)CC(c2ccccc2)(c2ccccc2)C2CN(C(=O)Cc3c[nH]c4ccccc34)CC21 -US20150141400A1,2,CC(C)(C)OC(=O)N1CCC[C@H](OCCN)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H](OCCNC(=O)OCc2ccccc2)C1 -US20070049582A1,4,NC=O.Nc1c(Br)cc(Cl)cc1C(=O)O>>O=c1[nH]cnc2c(Br)cc(Cl)cc12 -US04798827,6,CC(=O)SC1CN2CCC1CC2>>SC1CN2CCC1CC2 -US20100179218A1,2,COCC1CC1C(=O)Cl.Cc1cc(OCc2ccccc2)c(OCc2ccccc2)cc1C(=O)OCC(O)CNC(C)(C)CNC(=O)C1CCOC1>>COCC1CC1C(=O)OC(CNC(C)(C)CNC(=O)C1CCOC1)COC(=O)c1cc(OCc2ccccc2)c(OCc2ccccc2)cc1C -US20080207563A1,6,O=C(N[C@@H](Cc1ccc2ccccc2c1)C(=O)Nc1ccc(I)cc1F)OCC1c2ccccc2-c2ccccc21>>N[C@@H](Cc1ccc2ccccc2c1)C(=O)Nc1ccc(I)cc1F -US08673911B2,6,COC(=O)c1sc(CO[Si](C)(C)C(C)(C)C)cc1-c1ccccc1>>COC(=O)c1sc(CO)cc1-c1ccccc1 -US20130324579A1,7,Cc1nc2ccccc2n1CCn1cc([N+](=O)[O-])cn1>>Cc1nc2ccccc2n1CCn1cc(N)cn1 -US06093732,2,CCOC(=O)c1cnc2ccc([N+](=O)[O-])cc2c1O.NCc1ccc(Cl)cc1>>O=C(NCc1ccc(Cl)cc1)c1cnc2ccc([N+](=O)[O-])cc2c1O -US20070259851A1,7,O=C(Cc1cccc(F)c1[N+](=O)[O-])NC1CCN(Cc2ccccc2)CC1>>O=[N+]([O-])c1c(F)cccc1CCNC1CCN(Cc2ccccc2)CC1 -US20120101064A1,3,CC(C)(C)OC(=O)n1ccc2c(Br)cncc21.COC(=O)c1ccc(C#N)c(B2OC(C)(C)C(C)(C)O2)c1>>COC(=O)c1ccc(C#N)c(-c2cncc3c2ccn3C(=O)OC(C)(C)C)c1 -US20120184562A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cccc(Cl)n1>>CC(C)(C)OC(=O)Nc1cccc(Cl)n1 -US09150575B2,2,CNC.O=C(O)c1nc(Cl)ccc1C(F)(F)F>>CN(C)C(=O)c1nc(Cl)ccc1C(F)(F)F -US07960392B2,3,C#C[Si](C)(C)C.CCc1sc(Br)nc1C(=O)O>>CCc1sc(C#C[Si](C)(C)C)nc1C(=O)O -US20120094995A1,2,CN1C2CCC1([C@H](N)c1ccccc1)CC2.CSc1ncccc1C(=O)O>>CSc1ncccc1C(=O)N[C@H](c1ccccc1)C12CCC(CC1)N2C -US20090099181A1,3,C#Cc1ccc(Cl)cc1.C[S@@](=O)(=NC(=O)c1cncc(Br)c1)c1ccccc1>>C[S@@](=O)(=NC(=O)c1cncc(C#Cc2ccc(Cl)cc2)c1)c1ccccc1 -US08183262B2,1,Cc1cc(-c2ccc(Cl)cc2)nc(Cl)n1.Ic1c[nH]cn1>>Cc1cc(-c2ccc(Cl)cc2)nc(-n2cnc(I)c2)n1 -US04064270,1,CC(=Nc1ccc(NC(=O)C(C)Br)cc1)N(C)C.CCNCC>>CCN(CC)C(C)C(=O)Nc1ccc(N=C(C)N(C)C)cc1 -US05344843,1,COC(=O)C(=O)c1ccc(O)cc1.OCCOc1ccccc1F>>COC(=O)C(=O)c1ccc(OCCOc2ccccc2F)cc1 -US05151418,2,CN=C=O.FC(F)(F)c1ccc(OC2CNC2)cc1>>CNC(=O)N1CC(Oc2ccc(C(F)(F)F)cc2)C1 -US20070208036A1,6,O=C1c2ccccc2C(=O)N1C1CN(C(c2ccccc2)c2ccccc2)C1>>NC1CN(C(c2ccccc2)c2ccccc2)C1 -US05037845,1,CNS(=O)(=O)Cc1ccc2[nH]cc(CC#N)c2c1.ClCc1ccccc1>>CNS(=O)(=O)Cc1ccc2c(c1)c(CC#N)cn2Cc1ccccc1 -US20150031674A1,4,C[S+](C)(C)=O.O=C1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC2(CC1)CO2 -US08236837B2,3,CCOP(=O)(CC#N)OCC.O=C1CCc2ccc3nc(CCCCc4ccccc4)oc3c21>>N#CC=C1CCc2ccc3nc(CCCCc4ccccc4)oc3c21 -US05021439,3,COC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C.O=Cc1ccccc1>>COC(=O)[C@@H]1CC(C(O)c2ccccc2)C(=O)N1C(=O)OC(C)(C)C -US20080045530A1,2,C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1.COc1ccc2c(O[C@@H]3C[C@H](NC(=O)OC(C)(C)C)[C@H](C(=O)O)C3)cc(-c3ccccc3)nc2c1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)C[C@@H]1NC(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1 -US05728835,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCc1ccc(C(=O)Nc2ccccc2OC)cc1>>COc1ccccc1NC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1 -US07214690B2,1,CC(C)Oc1cc(C(F)(F)F)c2c3c(ccc2n1)N[C@H](C)CO3.CCC=O>>CCCN1c2ccc3nc(OC(C)C)cc(C(F)(F)F)c3c2OC[C@H]1C -US08163728B2,9,COC(=O)c1cc(OCc2c(-c3ccccc3)noc2C)n[nH]1.N>>Cc1onc(-c2ccccc2)c1COc1cc(C(N)=O)[nH]n1 -US20110092461A1,2,CC(C)S(=O)(=O)Cl.Nc1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cc1>>CC(C)S(=O)(=O)Nc1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cc1 -US20040063699A1,1,NCCN1CCN(C(c2ccccc2)c2ccccc2)CC1.O=Cc1ccccc1>>c1ccc(CNCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1 -US20090093484A1,3,C#CCO.CSc1ccc(Br)cc1>>CSc1ccc(C#CCO)cc1 -US07691876B2,2,CC(C)(C)c1ccc(CNCCc2ccc(Cl)c(C(F)(F)F)c2)cc1.CCOC(=O)c1ncc(F)c2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccc(Cl)c(C(F)(F)F)c2)C(=O)c2ncc(F)c3cc[nH]c23)cc1 -US04299767,7,CC(=O)OCCNC(=O)Nc1ccc(CNC(=O)CNC(=O)OCc2ccccc2)c(C(=O)c2ccccc2F)c1>>O=C(CNC(=O)OCc1ccccc1)NCc1ccc(NC(=O)NCCO)cc1C(=O)c1ccccc1F -US03958974,2,COc1ccc(N)cc1OC.O=C(Cl)CCCl>>COc1ccc(NC(=O)CCCl)cc1OC -US05595996,6,COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(=O)C=C4C[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)CC[C@]4(C)[C@H]3CC[C@@]21C>>CC(C)[Si](O[C@H]1CC[C@@]2(C)C(=CC(=O)[C@H]3[C@@H]4CC[C@H]([C@H](C)CCC(=O)O)[C@@]4(C)CC[C@@H]32)C1)(C(C)C)C(C)C -US08232284B2,9,Cn1ccc(Nc2ncnc3ccc(O)cc23)n1>>Cn1ccc(Nc2ncnc3ccccc23)n1 -US20150133473A1,7,C[C@H]1CN(c2ccncc2[N+](=O)[O-])C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>C[C@H]1CN(c2ccncc2N)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C -US20150252059A1,6,C#CCOc1cnc(C(=O)OC)c(C)n1>>C#CCOc1cnc(C(=O)O)c(C)n1 -US20120184736A1,1,CC(C)(C)c1ccc(O)cc1.Oc1cc(Cl)nnc1Cl>>CC(C)(C)c1ccc(Oc2nnc(Cl)cc2O)cc1 -US05847135,7,CC(C)(C)OC(=O)NC(CNc1ccccc1[N+](=O)[O-])C(=O)O>>CC(C)(C)OC(=O)N[C@@H](CNc1ccccc1N)C(=O)O -US07541365B2,7,CCOC(=O)C(C)(C)Oc1ccc2c(c1)C(=CCCN1CCC(O)(c3ccc(Cl)cc3)C(C)(C)C1)c1cccnc1CO2>>CC(C)(CO)Oc1ccc2c(c1)C(=CCCN1CCC(O)(c3ccc(Cl)cc3)C(C)(C)C1)c1cccnc1CO2 -US20120178736A1,1,CC(C)(O)C1CCN(Cc2nc3c(N4CCOCC4)nc(Cl)nc3[nH]2)CC1.CC(C)I>>CC(C)n1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(Cl)nc21 -US20120328569A1,6,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(CC3CCN(C(=O)OC(C)(C)C)CC3)S(C)(=O)=O)c(-c3cccc(-c4nc5ncccc5o4)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(CC3CCNCC3)S(C)(=O)=O)c(-c3cccc(-c4nc5ncccc5o4)c3)cc12 -US20090181963A1,2,CN.O=C(O)c1ccc(Cn2nnc3c(N4CCOCC4)nc(-c4cccc(O)c4)nc32)cc1>>CNC(=O)c1ccc(Cn2nnc3c(N4CCOCC4)nc(-c4cccc(O)c4)nc32)cc1 -US20070219210A1,2,CC(C)(C)N.COc1ccc(-n2nc(C(=O)O)cc2-c2cnccn2)cn1>>COc1ccc(-n2nc(C(=O)NC(C)(C)C)cc2-c2cnccn2)cn1 -US20150051197A1,6,O=S1(=O)CCN2C(=N1)C1(COCc3ccccc3)CCC2CC1>>O=S1(=O)CCN2C(=N1)C1(CO)CCC2CC1 -US20090324581A1,7,O=C(O)c1ccc(C2CCCCC2)c(Cl)c1>>OCc1ccc(C2CCCCC2)c(Cl)c1 -US20110301191A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.NCc1ccc(Cl)cc1Cl>>CC(C)(C)OC(=O)N1CCC(NCc2ccc(Cl)cc2Cl)CC1 -US20100120859A1,1,COC(=O)c1ccc(CBr)cc1.COCCCc1cc(O)cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1>>COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)cc(OCc2ccc(C(=O)OC)cc2)c1 -US20050026967A1,6,COC(=O)c1c(-c2ccccc2)noc1C>>Cc1onc(-c2ccccc2)c1C(=O)O -US04371468,8,OCc1ncn2c1CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2>>O=Cc1ncn2c1CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2 -US04548939,1,Cn1c(=O)c2c(ncn2CCCl)n(C)c1=O.c1ccc2c(C3CCNCC3)c[nH]c2c1>>Cn1c(=O)c2c(ncn2CCN2CCC(c3c[nH]c4ccccc34)CC2)n(C)c1=O -US04372953,3,O=C(Cl)CCCCCCl.c1ccccc1>>O=C(CCCCCCl)c1ccccc1 -US20110166344A1,2,CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1NCCC(C)C.O=C(O)CC1=NS(=O)(=O)c2cc(I)ccc2N1>>CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1N(CCC(C)C)C(=O)CC1=NS(=O)(=O)c2cc(I)ccc2N1 -US20150119380A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1c(O)cc(F)cc1F>>CC(C)(C)OC(=O)N1CCN(c2cc(O)c(C=O)c(F)c2)CC1 -US20110245264A1,6,CC(C)(C)OC(=O)N[C@@H](CO)c1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)N[C@@H](CO)c1ccc(O)cc1 -US20110250135A1,2,O=C(O)c1ccc(Br)nc1.[NH3+]CC(=O)N1CCN(c2ccc(OCc3ccccc3)cc2)CC1>>O=C(NCC(=O)N1CCN(c2ccc(OCc3ccccc3)cc2)CC1)c1ccc(Br)nc1 -US06706725B1,3,CCC1(c2cccs2)OCCO1.CN(C)C=O>>CCC1(c2ccc(C=O)s2)OCCO1 -US20100041892A1,1,COCCBr.O=[N+]([O-])c1cc(O)ccc1I>>COCCOc1ccc(I)c([N+](=O)[O-])c1 -US05166152,6,CCOC(=O)c1nn(-c2ccccc2)c2c1CSc1ccc(C(=O)OC(C)(C)C)cc1-2>>CCOC(=O)c1nn(-c2ccccc2)c2c1CSc1ccc(C(=O)O)cc1-2 -US05616801,6,CCc1ccc(-c2ccc(N(C(C)=O)c3ccc(C)cc3)cc2)cc1>>CCc1ccc(-c2ccc(Nc3ccc(C)cc3)cc2)cc1 -US07662825B2,1,NCc1ccc(CO)o1.O=S(=O)(Nc1nccnc1Cl)c1cccc(Cl)c1Cl>>NCc1ccc(COc2nccnc2NS(=O)(=O)c2cccc(Cl)c2Cl)o1 -US20090012093A1,7,Cc1cccc(C)c1-c1cccc(C=O)c1>>Cc1cccc(C)c1-c1cccc(CO)c1 -US08461330B2,1,COC(CBr)OC.Oc1ccc2ncccc2c1>>COC(COc1ccc2ncccc2c1)OC -US06353006B1,1,BrC1CCCC1.Cc1ccc([N+](=O)[O-])c(N=C2NC3(CCCC3)CS2)c1C>>Cc1ccc([N+](=O)[O-])c(N=C2SCC3(CCCC3)N2C2CCCC2)c1C -US07618978B2,6,COC(=O)c1cc(Br)cc(C(=O)OC)c1>>COC(=O)c1cc(Br)cc(C(=O)O)c1 -US20120190666A1,2,Cc1nc(N)cc(-c2c(Nc3ccc(N)cc3)nc3cccnn23)n1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1nc(N)cc(-c2c(Nc3ccc(NC(=O)Oc4ccc([N+](=O)[O-])cc4)cc3)nc3cccnn23)n1 -US20140093823A1,2,O=C(Nc1ccccc1)C(F)(F)S(=O)(=O)F.OC(CC1(c2ccccc2)OCCO1)C(F)(F)F>>O=C(Nc1ccccc1)C(F)(F)S(=O)(=O)OC(CC1(c2ccccc2)OCCO1)C(F)(F)F -US20080194617A1,2,CCOC(=O)Cl.Cc1nn(C)c(-n2ccc3cc(Cl)ccc32)c1CCS(N)(=O)=O>>CCOC(=O)NS(=O)(=O)CCc1c(C)nn(C)c1-n1ccc2cc(Cl)ccc21 -US07189722B2,2,Nc1ccc2c(c1)CCC1(C2)NC(=O)NC1=O.O=C(O)c1cccc(Cl)c1>>O=C1NC(=O)C2(CCc3cc(NC(=O)c4cccc(Cl)c4)ccc3C2)N1 -US20080096861A1,1,NCCc1ccccn1.O=[N+]([O-])c1ccccc1Cl>>O=[N+]([O-])c1ccccc1NCCc1ccccn1 -US20090111820A1,2,CN=C=S.Cc1cccc(-c2cc([C@H]3C[C@H]4C[C@H]4N3)no2)c1>>CNC(=S)N1[C@@H](c2cc(-c3cccc(C)c3)on2)C[C@H]2C[C@H]21 -US04012389,7,O=C1NCCN(CC2(OCc3ccccc3)C=CC=CC2)C1c1ccccc1>>C1=CCC(CN2CCNCC2c2ccccc2)(OCc2ccccc2)C=C1 -US20140329797A1,1,N#CC1CCNCC1.O=c1ccc(-c2nc(-c3ccc(C4(C(F)(F)F)CC4)cc3)no2)cn1Cc1cccc(Br)c1>>N#CC1CCN(c2cccc(Cn3cc(-c4nc(-c5ccc(C6(C(F)(F)F)CC6)cc5)no4)ccc3=O)c2)CC1 -US05117009,1,CCOC(=O)CCCCBr.O=c1c2ccccc2oc2ccc(O)cc12>>CCOC(=O)CCCCOc1ccc2oc3ccccc3c(=O)c2c1 -US20080171740A1,1,CC(C)(C)OC(=O)NCCCCCNC1CCCc2cccnc21.O=Cc1cn2ccccc2n1>>CC(C)(C)OC(=O)NCCCCCN(Cc1cn2ccccc2n1)C1CCCc2cccnc21 -US05840732,7,CCOC(=O)CCCSc1nccc(N)n1>>Nc1ccnc(SCCCCO)n1 -US20120114765A1,2,CN1CCC(N)CC1.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>CN1CCC(NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)CC1 -US06166006,1,COc1ccc(N2CCNCC2)cc1.Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CCl)cc3)c2)cc1>>COc1ccc(N2CCN(Cc3ccc(NC(=O)/C=C/c4cccc(-c5ccc(C)cc5)c4)cc3)CC2)cc1 -US04758577,2,C1=Cc2ccccc2C(C2CCNCC2)c2ccccc21.O=C(Cl)C=Cc1ccccc1>>O=C(C=Cc1ccccc1)N1CCC(C2c3ccccc3C=Cc3ccccc32)CC1 -US07790898B2,2,COc1cccc(C2(O)CCCNC2)c1.O=C(Cl)c1ccccc1Br>>COc1cccc(C2(O)CCCN(C(=O)c3ccccc3Br)C2)c1 -US20050020634A1,7,CCOC(=O)C=Cc1cccc(-c2c(CC(=O)Nc3ccc(F)cc3C(F)(F)F)c(=O)oc3cc(Cl)c(C)cc23)c1>>CCOC(=O)CCc1cccc(-c2c(CC(=O)Nc3ccc(F)cc3C(F)(F)F)c(=O)oc3cc(Cl)c(C)cc23)c1 -US20090258886A1,7,O=Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(CO)c1 -US20140128255A1,3,CC#C[Mg+].O=C(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl>>CC#CC(O)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl -US07858621B2,2,CC(C)Oc1nc(C(F)(F)F)ccc1C=CC(=O)O.CS(=O)(=O)Nc1ccc(CN)cc1F>>CC(C)Oc1nc(C(F)(F)F)ccc1C=CC(=O)NCc1ccc(NS(C)(=O)=O)c(F)c1 -US06150373,1,CCN(CC)CCCl.N#Cc1ccc(O)cc1>>CCN(CC)CCOc1ccc(C#N)cc1 -US20090118284A1,1,C=C(CBr)C(=O)OC.CNC>>C=C(CN(C)C)C(=O)OC -US20120214840A1,2,CCOC(=O)c1cn2cc(CO)ccc2c1-c1ccc(F)cc1.CS(=O)(=O)Cl>>CCOC(=O)c1cn2cc(COS(C)(=O)=O)ccc2c1-c1ccc(F)cc1 -US20110046113A1,6,Cn1ccnc1CN(Cc1ccc(S(=O)(=O)NCCCCNC(=O)OC(C)(C)C)cc1)Cc1ncc[nH]1>>Cn1ccnc1CN(Cc1ccc(S(=O)(=O)NCCCCN)cc1)Cc1ncc[nH]1 -US20080125590A1,3,O=C1Cc2cccc(Cl)c2N1.O=Cc1ccc2cccccc1-2>>O=C1Nc2c(Cl)cccc2/C1=C/c1ccc2cccccc1-2 -US04352930,9,CCOC(=O)CC(=O)OCC.N>>CCOC(=O)CC(N)=O -US06441017B1,2,N#Cc1ccc(Cn2cncc2CC(=O)[O-])cc1F.N[C@@H]1CCN(c2cccc3ccc(O)cc23)C1=O>>N#Cc1ccc(Cn2cncc2CC(=O)N[C@@H]2CCN(c3cccc4ccc(O)cc34)C2=O)cc1F -US20120142724A1,1,CI.C[C@@H](c1ccccc1)N(Cc1ccccc1)[C@@H](C)CCO>>COCC[C@H](C)N(Cc1ccccc1)[C@@H](C)c1ccccc1 -US07208495B2,1,COc1cccc(CCOS(C)(=O)=O)c1.Cc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)(C)C2N1CCCC1>>COc1cccc(CCN2CCN(c3c(C)c(C)c4c(c3C)C(N3CCCC3)C(C)(C)O4)CC2)c1 -US20140206681A1,2,CNC(=O)Cl.Nc1nccn2c([C@@H]3CC[C@@H](CO)NC3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c12>>CNC(=O)N1C[C@H](c2nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c3c(N)nccn23)CC[C@H]1CO -US20130217664A1,6,COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1N(C)c1cc2c(cn1)ncn2C>>COc1cc(C2CCNCC2)ccc1N(C)c1cc2c(cn1)ncn2C -US07977371B2,7,CCOC(=O)c1ccc(-c2cc(C(N)=O)c(NC(N)=O)[nH]2)cc1>>NC(=O)Nc1[nH]c(-c2ccc(CO)cc2)cc1C(N)=O -US20140024634A1,1,COc1cccc(C=O)c1.Oc1cc(CC(F)(F)F)c(-c2ccc3c(-c4nc5c([nH]4)CCNC5)n[nH]c3c2)cc1F>>COc1cccc(CN2CCc3[nH]c(-c4n[nH]c5cc(-c6cc(F)c(O)cc6CC(F)(F)F)ccc45)nc3C2)c1 -US06372759B1,6,CC(C)(C)[Si](C)(C)Oc1ccc(N2C(=O)c3ccccc3C2=O)c(NC(=O)OCC2CCN(c3ccncc3)CC2)c1>>CC(C)(C)[Si](C)(C)Oc1ccc(N)c(NC(=O)OCC2CCN(c3ccncc3)CC2)c1 -US07977485B2,2,C1=CCNC1.O=C(O)c1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1>>O=C(N[C@H]1CN2CCC1CC2)c1cc2cccc(-c3cccc(C(=O)N4CC=CC4)c3)c2s1 -US20050101063A1,3,C#C[Si](C)(C)C.O=Cc1ccc(I)cc1>>C[Si](C)(C)C#Cc1ccc(C=O)cc1 -US20050085524A1,7,N#Cc1ccc(-c2ccc(OC(F)F)cc2)cc1>>NCc1ccc(-c2ccc(OC(F)F)cc2)cc1 -US03960967,1,CC(=O)OCC=C(C)CCl.O=S([O-])c1ccc(C(F)(F)F)cc1>>CC(=O)OCC=C(C)CS(=O)(=O)c1ccc(C(F)(F)F)cc1 -US08921576B2,9,CC(=O)N1CCC2(C1)CN(C(=O)C(F)(F)F)c1ccc(S(=O)(=O)Cl)cc12>>CC(=O)N1CCC2(C1)CN(C(=O)C(F)(F)F)c1ccc(S)cc12 -US20120302549A1,2,CC1(C)C[C@@]2(N=C(N)OCC2(F)F)c2cc(N)ccc2O1.O=C(O)c1ccc(Cl)cn1>>CC1(C)C[C@@]2(N=C(N)OCC2(F)F)c2cc(NC(=O)c3ccc(Cl)cn3)ccc2O1 -US20090041723A1,2,Cn1cc(C#Cc2ccc(NC(=O)C3COCCN3C(=O)C(N)c3ccccc3)cc2)c(-c2cc(Cl)ccc2O)n1.O=C(Cl)N1CCOCC1>>Cn1cc(C#Cc2ccc(NC(=O)C3COCCN3C(=O)C(NC(=O)N3CCOCC3)c3ccccc3)cc2)c(-c2cc(Cl)ccc2O)n1 -US05597845,1,COc1cc(CN(C)C(=O)[C@H](Cc2ccccc2)N(CC=O)C(=O)OC(C)(C)C)cc(OC)c1OC.N[C@H](CC(=O)O)Cc1c[nH]c2ccccc12>>COc1cc(CN(C)C(=O)[C@H](Cc2ccccc2)N(CCN[C@H](CC(=O)O)Cc2c[nH]c3ccccc23)C(=O)OC(C)(C)C)cc(OC)c1OC -US20030087955A1,6,COc1ccc(CC(=O)c2c(OC)cc(OC)cc2OC)c(OC)c1>>COc1ccc(CC(=O)c2c(O)cc(OC)cc2OC)c(OC)c1 -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1)Oc1ccccc1>>O=C(NCCOc1ccc(CC(Oc2ccccc2)C(=O)O)cc1)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US20020133015A1,3,COC(=O)[C@H](Cc1ccc(I)cc1)NC(=O)OC(C)(C)C.Cc1cc(C(F)(F)F)n(C)c(=O)c1I>>COC(=O)[C@H](Cc1ccc(-c2c(C)cc(C(F)(F)F)n(C)c2=O)cc1)NC(=O)OC(C)(C)C -US07449466B2,1,CS(=O)(=O)OCCCC1CCCCC1.Fc1cc(N2CCNCC2)ccc1OCc1ccccc1>>Fc1cc(N2CCN(CCCC3CCCCC3)CC2)ccc1OCc1ccccc1 -US20120178736A1,3,CC1(C)OB(c2ccnc3ccccc23)OC1(C)C.Cn1c(CN2CCN(C(C)(C)C)CC2)nc2c(N3CCOCC3)nc(Cl)nc21>>Cn1c(CN2CCN(C(C)(C)C)CC2)nc2c(N3CCOCC3)nc(-c3ccnc4ccccc34)nc21 -US04789395,8,CCOC(=O)c1c(C(F)(F)F)nc(C(F)F)c(Sc2ccccc2)c1CC.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1c(C(F)(F)F)nc(C(F)F)c(S(=O)c2ccccc2)c1CC -US20100222299A1,1,COc1cc2c(cc1OCc1ccccc1)CC(C)NC2.COc1ccc(OC)c(CCl)c1>>COc1ccc(OC)c(CN2Cc3cc(OC)c(OCc4ccccc4)cc3CC2C)c1 -US20100010053A1,6,CCOC(=O)CCc1c[nH]c2cc(-c3noc(-c4cnc(OC(C)C)c(C(F)(F)F)c4)n3)ccc12>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(CCC(=O)O)c[nH]c4c3)no2)cc1C(F)(F)F -US05962451,1,CNC.N#Cc1cccc(C=O)c1>>CN(C)Cc1cccc(C#N)c1 -US20150141428A1,2,C#CC(C)NCc1cccc(-c2nccs2)c1.O=C=Nc1ccc(OC(F)(F)F)cc1>>C#CC(C)N(Cc1cccc(-c2nccs2)c1)C(=O)Nc1ccc(OC(F)(F)F)cc1 -US08318949B2,1,CCOC(=O)CBr.CCOC(=O)c1sc(N2CCNC2=O)nc1C>>CCOC(=O)CN1CCN(c2nc(C)c(C(=O)OCC)s2)C1=O -US20130028843A1,9,[N-]=[N+]=NCc1cccc2ccc(Cl)cc12>>NCc1cccc2ccc(Cl)cc12 -US07943610B2,2,CC(=O)Cl.CCCn1nc2c(N)nc3ccccc3c2c1NCCC1CCNCC1>>CCCn1nc2c(N)nc3ccccc3c2c1NCCC1CCN(C(C)=O)CC1 -US06222048B1,3,CC1(C)C=C(I)C(=O)C1.OB(O)c1ccccc1>>CC1(C)C=C(c2ccccc2)C(=O)C1 -US07550461B2,2,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)O)cc2)CC1.COc1c(NC(=O)c2cc3cccc(N)c3s2)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)c2cc3cccc(NC(=O)c4ccc(S(=O)(=O)N5CCN(C(=O)OC(C)(C)C)CC5)cc4)c3s2)cc(C(C)(C)C)cc1NS(C)(=O)=O -US20130131068A1,2,CNC(=O)c1nc(C(F)(F)F)n2c1CNCC2.O=C(O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1>>CNC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)c1cccc(Cc3n[nH]c(=O)c4ccccc34)c1)CC2 -US20100120757A1,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)c2c1OC1(CCCC1)C2.O=C(CCl)OC(=O)CCl>>COc1ccc(C2=NN(C3CCN(C(=O)CCl)CC3)C(=O)C2(C)C)c2c1OC1(CCCC1)C2 -US04774369,3,C#C.CC/C=C(\F)C=O>>C#CC(O)/C(F)=C/CC -US06713474B2,6,COc1cc(-c2cn(C3CCC4(CC3)OCCO4)c3ncnc(N)c23)ccc1N>>COc1cc(-c2cn(C3CCC(=O)CC3)c3ncnc(N)c23)ccc1N -US20150238601A1,1,CC(C)(C)OC(=O)N1CCCC(CO)C1.Oc1cccc(Br)c1>>CC(C)(C)OC(=O)N1CCCC(COc2cccc(Br)c2)C1 -US20090012063A1,3,CCCCCCc1cccc(-c2nc(I)c(C(=O)N3CCC(N4CCCC4)CC3)n2C)c1.OB(O)c1ccncc1>>CCCCCCc1cccc(-c2nc(-c3ccncc3)c(C(=O)N3CCC(N4CCCC4)CC3)n2C)c1 -US06974831B2,6,CCc1c(C(=O)C(N)=O)c2c(OCC(=O)OC)cc3c(c2n1Cc1ccccc1)CCC3>>CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3c(c2n1Cc1ccccc1)CCC3 -US06420409B1,2,CCCC(O)CS(=O)(=O)NC(C)(C)C.O=C(O)c1ccccc1>>CCCC(CS(=O)(=O)NC(C)(C)C)OC(=O)c1ccccc1 -US08664233B2,1,C1CNCCN1.CCOc1nc(Cl)nc2c1[nH]c1c(Br)cccc12>>CCOc1nc(N2CCNCC2)nc2c1[nH]c1c(Br)cccc12 -US20120115869A1,1,C#Cc1cccc(C=O)c1.Nc1cc(-c2nnn[nH]2)ccc1F>>C#Cc1cccc(CNc2cc(-c3nnn[nH]3)ccc2F)c1 -US05908932,9,O=C1OCc2c1c(Cl)nc1ccccc21>>O=C1OCc2c1cnc1ccccc21 -US20040086866A1,5,CCOC(=O)C(F)(F)F.NCCCCCC(=O)O>>O=C(O)CCCCCNC(=O)C(F)(F)F -US20060229314A1,1,CCOC(=O)c1c(N2CCN(C(=O)c3ccco3)CC2)c2sccc2[nH]c1=O.Fc1cccc(CBr)c1>>CCOC(=O)c1c(N2CCN(C(=O)c3ccco3)CC2)c2sccc2n(Cc2cccc(F)c2)c1=O -US20140163012A1,6,CC(C)(C)OC(=O)N1CCc2c(sc3cc(-n4ccc(OCc5ccc(Cl)cn5)cc4=O)ccc23)C1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc2c3c(sc2c1)CNCC3 -US20090270361A1,2,CC(C)N.Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Cc1ccc(C(=O)O)cc1>>Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Cc1ccc(C(=O)NC(C)C)cc1 -US20150252038A1,6,COC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN(CC3(C(F)(F)F)CCCC3)C2)cc1F>>O=C(O)c1cc(C2CC2)c(O[C@@H]2CCCN(CC3(C(F)(F)F)CCCC3)C2)cc1F -US20070265270A1,1,COc1ccc(C(O)C(C)NC(=O)CCl)cc1>>COc1ccc(C2OCC(=O)NC2C)cc1 -US20080249102A1,2,CC(C)(C)[C@H](N)C(=O)O.CS(=O)(=O)Cl>>CC(C)(C)[C@H](NS(C)(=O)=O)C(=O)O -US20090192194A1,3,CC1(C)OC(=O)CC(=O)O1.CC1CC(=O)CCN1C(=O)OC(C)(C)C>>CC1CC(=C2C(=O)OC(C)(C)OC2=O)CCN1C(=O)OC(C)(C)C -US20090221711A1,2,COc1cc(S(=O)(=O)Cl)ccc1Cl.NC(CO)C(C(F)(F)F)C(F)(F)F>>COc1cc(S(=O)(=O)NC(CO)C(C(F)(F)F)C(F)(F)F)ccc1Cl -US20100278833A1,1,COC(=O)c1sc(-n2cnc3ccncc32)cc1O.Fc1ccc(CBr)c(C(F)(F)F)c1>>COC(=O)c1sc(-n2cnc3ccncc32)cc1OCc1ccc(F)cc1C(F)(F)F -US20050113346A1,2,CC#CCOc1ccc(S(=O)(=O)Cl)cc1.CCOC(=O)C1CN(C(=O)N2CCOCC2)CCN1>>CC#CCOc1ccc(S(=O)(=O)N2CCN(C(=O)N3CCOCC3)CC2C(=O)OCC)cc1 -US20110212930A1,4,CC(C)(C)OC(=O)N1CCc2cc(N)ccc21.O=C(Cl)CCCCBr>>CC(C)(C)OC(=O)N1CCc2cc(N3CCCCC3=O)ccc21 -US07790728B2,8,O=C(Nc1cnc(Br)c(-c2cccnc2)n1)C1CC1.O=C(OO)c1cccc(Cl)c1>>O=C(Nc1cnc(Br)c(-c2ccc[n+]([O-])c2)n1)C1CC1 -US08415378B2,3,COC(=O)c1ccnc(Cl)c1.Fc1ccc(C[Zn+])c(F)c1>>COC(=O)c1ccnc(Cc2ccc(F)cc2F)c1 -US04617388,2,CN(C)S(=O)(=O)Cl.NS(=O)(=O)c1ccccc1O>>CN(C)S(=O)(=O)Oc1ccccc1S(N)(=O)=O -US20120165344A1,2,CN.O=C(O)c1c(-c2ccc(Br)cc2)oc2ccc(O)c(F)c12>>CNC(=O)c1c(-c2ccc(Br)cc2)oc2ccc(O)c(F)c12 -US20120094981A1,1,N#Cc1ccc(F)cc1C(F)(F)F.N[C@H]1CC[C@H](O)CC1>>N#Cc1ccc(NC2CCC(O)CC2)cc1C(F)(F)F -US20110076276A1,1,CC(C)I.Cc1cc(C#N)cc(C(=O)c2[nH]c(=O)[nH]c(=O)c2C(C)C)c1>>Cc1cc(C#N)cc(C(=O)c2c(C(C)C)c(=O)[nH]c(=O)n2C(C)C)c1 -US20140249137A1,6,CC(=O)OC/C=C/c1cnc(-c2ccccc2)nc1Nc1cc(C2CC2)n(C(C)=O)n1>>CC(=O)OC/C=C/c1cnc(-c2ccccc2)nc1Nc1cc(C2CC2)[nH]n1 -US20120101083A1,6,CC(C)(C)OC(=O)N1CCc2ccc(-c3noc(-c4ccc(N5CC(F)C5)c(C#N)c4)n3)cc2CC1>>N#Cc1cc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)ccc1N1CC(F)C1 -US20060287457A1,6,C=CC(=O)NCCCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)OCC>>C=CC(=O)NCCCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)O -US20120108577A1,2,NC1CCN(CCn2c(=O)ccc3c(F)cc(F)cc32)CC1.O=C(O)C1COc2ccccc2O1>>O=C(NC1CCN(CCn2c(=O)ccc3c(F)cc(F)cc32)CC1)C1COc2ccccc2O1 -US20150252030A1,1,COC(=O)CBr.Cc1cc(C)c(O)c(-c2cccs2)c1>>COC(=O)COc1c(C)cc(C)cc1-c1cccs1 -US06787543B2,1,CN1CCNCC1C(c1ccccc1)c1ccccc1.COc1ccccc1C=O>>COc1ccccc1CN1CCN(C)C(C(c2ccccc2)c2ccccc2)C1 -US20050222213A1,7,O=C(O)/C(=C\c1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1>>O=C(O)C(Cc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 -US06017919,2,C1COCCN1.CCCCCOc1cc(C(=O)O)ccc1OC>>CCCCCOc1cc(C(=O)N2CCOCC2)ccc1OC -US20150094328A1,1,Cc1cnc(CBr)s1.O=C(N[C@H]1CCCC[C@@H]1O)c1c[nH]c2c(Cl)ccnc12>>Cc1cnc(Cn2cc(C(=O)N[C@H]3CCCC[C@@H]3O)c3nccc(Cl)c32)s1 -US20030176454A1,1,Fc1ccc(-c2cccc3c(Cl)nccc23)cc1.Nc1cccc(-n2ccnc2)c1>>Fc1ccc(-c2cccc3c(Nc4cccc(-n5ccnc5)c4)nccc23)cc1 -US20090216014A1,2,Nc1ccnc2cc(C(F)(F)F)ccc12.O=C(Cl)CCCCBr>>O=C(CCCCBr)Nc1ccnc2cc(C(F)(F)F)ccc12 -US20120245137A1,1,CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCC(=O)CC1.NCc1ccccc1>>CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCC(NCc2ccccc2)CC1 -US20120046418A1,1,CCOC(=O)CCCCCBr.O=Cc1c(O)ccc2ccccc12>>CCOC(=O)CCCCCOc1ccc2ccccc2c1C=O -US20040266839A1,1,CCI.Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCc4ccc5ccccc5c4)cc3)c2)o1>>CCN(Cc1ccc2ccccc2c1)C(=O)c1ccc(-c2cc(-c3nnc(C)o3)ccc2C)cc1 -US20130274469A1,2,CC1(N)CC1.Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2(C)CC2)cn1 -US20060287291A1,2,CC(C)(C)OC(=O)N1CCN(c2cc(N)cc3ccoc23)CC1.O=S(=O)(Cl)c1ccccc1Cl>>CC(C)(C)OC(=O)N1CCN(c2cc(NS(=O)(=O)c3ccccc3Cl)cc3ccoc23)CC1 -US08691991B2,1,CCOC(=O)c1ncc(Cc2ccc(F)cc2)cc1N.O=CCN1C(=O)c2ccccc2C1=O>>CCOC(=O)c1ncc(Cc2ccc(F)cc2)cc1NCCN1C(=O)c2ccccc2C1=O -US20140350019A1,6,CCOC(=O)COc1ccc(F)c(NCc2c(F)ccc(-c3cccc(F)c3)c2F)c1F>>O=C(O)COc1ccc(F)c(NCc2c(F)ccc(-c3cccc(F)c3)c2F)c1F -US04221815,2,CCOC(=O)c1ccc(N)cc1OCC.COc1ccc(Cl)cc1C(=O)Cl>>CCOC(=O)c1ccc(NC(=O)c2cc(Cl)ccc2OC)cc1OCC -US06455725B1,7,COC(=O)C=Cc1cc(Cl)ccc1C(=O)OC>>COC(=O)CCc1cc(Cl)ccc1C(=O)OC -US06605620B1,3,CCOC(=O)c1cccnc1Cl.COc1cc(B(O)O)cc(OC)c1OC>>CCOC(=O)c1cccnc1-c1cc(OC)c(OC)c(OC)c1 -US20120095034A1,7,COc1cc([N+](=O)[O-])cnc1Cl>>COc1cc(N)cnc1Cl -US20130040930A1,2,CS(=O)(=O)c1cc(N2CCCS2(=O)=O)ccc1C(=O)O.O=C(c1ccc(Cl)cc1)C1CCNCC1>>CS(=O)(=O)c1cc(N2CCCS2(=O)=O)ccc1C(=O)N1CCC(C(=O)c2ccc(Cl)cc2)CC1 -US20110097269A1,1,COc1ccc(OCCOS(C)(=O)=O)c(C=O)c1.Nc1cc(F)ccc1Oc1ccccc1>>COc1ccc(OCCOS(C)(=O)=O)c(CNc2cc(F)ccc2Oc2ccccc2)c1 -US20050054711A1,3,Brc1ccc2c(c1)C1(CCCCC1)C(=NOCc1ccccc1)N2.OB(O)c1ccc(F)cc1>>Fc1ccc(-c2ccc3c(c2)C2(CCCCC2)C(=NOCc2ccccc2)N3)cc1 -US07081454B2,7,Cc1cc(-n2ccnc2)ccc1[N+](=O)[O-]>>Cc1cc(-n2ccnc2)ccc1N -US03980650,2,C1CNCCN1.O=C(Cl)c1ccco1>>O=C(c1ccco1)N1CCNCC1 -US20080146612A1,3,CCOC(=O)c1ccccc1B1OC(C)(C)C(C)(C)O1.O=C(NCC1(O)CCCCCC1)c1cc(I)ccc1Cl>>CCOC(=O)c1ccccc1-c1ccc(Cl)c(C(=O)NCC2(O)CCCCCC2)c1 -US20110130406A1,6,CCN1CCC(COc2nn(Cc3ccc(OC)cc3)c3nccc(Oc4ccc(Nc5ncccc5C(=O)Nc5ccc(F)cc5)cc4F)c23)CC1>>CCN1CCC(COc2n[nH]c3nccc(Oc4ccc(Nc5ncccc5C(=O)Nc5ccc(F)cc5)cc4F)c23)CC1 -US20080132482A1,2,O=C(Cl)CCC1CCCC1.O=C1N[C@H](Cc2ccccc2)CO1>>O=C(CCC1CCCC1)N1C(=O)OC[C@H]1Cc1ccccc1 -US08623866B2,2,C1CNC1.COC(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1>>Cn1cc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)c(C(=O)N2CCC2)n1 -US20140364414A1,3,Brc1cnc(N2CCOCC2)c2nc(CCc3ccc4ccccc4n3)cn12.COC(=O)C(O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>COC(=O)C(O)c1ccc(-c2cnc(N3CCOCC3)c3nc(CCc4ccc5ccccc5n4)cn23)cc1 -US06372917B1,1,CS(=O)(=O)c1cc(CBr)ccc1Br.O=Cc1[nH]c(-c2ccccc2)nc1Cl>>CS(=O)(=O)c1cc(Cn2c(-c3ccccc3)nc(Cl)c2C=O)ccc1Br -US07645781B2,9,CCn1c(=O)oc2cc(N3C[C@H](C(=O)OC)OC3=O)cc(F)c21.N>>CCn1c(=O)oc2cc(N3C[C@H](C(N)=O)OC3=O)cc(F)c21 -US05541195,6,O=C(N(Cc1ccnc2ccccc12)[C@H]1CCN(CC(c2ccccc2)c2ccccc2)[C@H](Cc2ccccc2)C1)C(F)(F)F>>c1ccc(C[C@@H]2C[C@@H](NCc3ccnc4ccccc34)CCN2CC(c2ccccc2)c2ccccc2)cc1 -US09096600B2,2,COc1c(C(C)=O)cc(Cl)c(C)c1-c1ccc(C(=O)O)c(F)c1.N#CC1CNC1>>COc1c(C(C)=O)cc(Cl)c(C)c1-c1ccc(C(=O)N2CC(C#N)C2)c(F)c1 -US08318760B2,3,COC(=O)c1cc(Br)ccc1N.OB(O)c1ccc(OC(F)(F)F)cc1>>COC(=O)c1cc(-c2ccc(OC(F)(F)F)cc2)ccc1N -US20090270402A1,3,CC(C)c1nnc2ccc(I)nn12.Cc1onc(-c2ccc(F)cc2F)c1I>>Cc1onc(-c2ccc(F)cc2F)c1-c1ccc2nnc(C(C)C)n2n1 -US20110263658A1,7,COCCCc1ccccc1-c1cc(C(F)(F)F)c(C(=O)OC)cn1>>COCCCc1ccccc1-c1cc(C(F)(F)F)c(CO)cn1 -US06583135B2,1,CC(C)(C)OC(=O)N1CCc2[nH]c3cc(Cl)c(Cl)cc3c2CC1.CCOC(=O)CBr>>CCOC(=O)Cn1c2c(c3cc(Cl)c(Cl)cc31)CCN(C(=O)OC(C)(C)C)CC2 -US20070191385A1,6,CC(C)(C)OC(=O)Nc1cccc(C2=CC(=O)N(C(C)(C)C)S2(=O)=O)c1>>CC(C)(C)N1C(=O)C=C(c2cccc(N)c2)S1(=O)=O -US20150175623A1,3,C#CCO.Cc1c(Br)ccc(I)c1Cl>>Cc1c(Br)ccc(C#CCO)c1Cl -US20100152266A1,6,CCOC(=O)c1cn(C)nc1I>>Cn1cc(C(=O)O)c(I)n1 -US20150045378A1,7,COC(=O)c1cnc(Cl)c(OCc2ccccc2)c1>>OCc1cnc(Cl)c(OCc2ccccc2)c1 -US20150175602A1,6,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccccc2F)CC1>>O=S(=O)(c1ccccc1F)C1CCNCC1 -US04771045,9,COC(=O)CS[C@H]1NC(=O)[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1.N>>NC(=O)CS[C@H]1NC(=O)[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20060172989A1,1,BrCCCBr.O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccc(O)cc1>>O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccc(OCCCBr)cc1 -US20040192680A1,3,CCOP(=O)(CC(=O)NC1CCCCC1O)OCC.O=Cc1ccccc1SC1CCCCC1>>O=C(/C=C/c1ccccc1SC1CCCCC1)NC1CCCCC1O -US04024128,2,CC(C)NC(=O)N1CCc2ccc(S(N)(=O)=O)cc2CC1.O=C=NC1CCCCC1>>CC(C)NC(=O)N1CCc2ccc(S(=O)(=O)NC(=O)NC3CCCCC3)cc2CC1 -US04423058,2,CC(C)(C)n1cc(O)cn1.CCNC(=O)F>>CCNC(=O)Oc1cnn(C(C)(C)C)c1 -US06262056B1,6,CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2s1>>O=C(O)c1cc2cc([N+](=O)[O-])ccc2s1 -US08324221B2,6,CC(C)C1CCc2ncnc(N3CC4(CCN(Cc5ccccc5)CC4)c4c(CNC(=O)OC(C)(C)C)cccc43)c21>>CC(C)C1CCc2ncnc(N3CC4(CCN(Cc5ccccc5)CC4)c4c(CN)cccc43)c21 -US20130231328A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(C#N)OC)CC4)CC1>>COC(C#N)C[C@H]1CCc2sc3ncnc(OC4CCC(N(C)C(=O)OC(C)(C)C)CC4)c3c21 -US04167638,7,COc1cc([N+](=O)[O-])c2nc(NC(C)=O)ccc2c1>>COc1cc(N)c2nc(NC(C)=O)ccc2c1 -US04968679,2,CCCN(CCC)C1CCc2cccc(CN)c2C1.O=CO>>CCCN(CCC)C1CCc2cccc(CNC=O)c2C1 -US20080171732A1,2,CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1OC.NS(=O)(=O)Cc1ccccc1F>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)Cc3ccccc3F)C2)nc1OC -US05464796,7,O=C(O)c1c(F)c(Cl)c(F)c(F)c1[N+](=O)[O-]>>Nc1c(F)c(F)c(Cl)c(F)c1C(=O)O -US06300363B1,2,CCC(=O)Cl.Nc1c(C(=O)c2cc(Cl)ccc2[N+](=O)[O-])[nH]c2cc(Cl)ccc12>>CCC(=O)Nc1c(C(=O)c2cc(Cl)ccc2[N+](=O)[O-])[nH]c2cc(Cl)ccc12 -US20070208001A1,2,Cc1cc(Br)ccc1C1(O)CCC(C(=O)O)CC1.N[C@@H]1CC[C@H](O)CC1>>Cc1cc(Br)ccc1C1(O)CCC(C(=O)N[C@@H]2CC[C@H](O)CC2)CC1 -US20140249157A1,7,CC1CN(C)CCN1c1ccncc1[N+](=O)[O-]>>CC1CN(C)CCN1c1ccncc1N -US05488140,8,OCCCCOCc1ccccc1>>O=CCCCOCc1ccccc1 -US20120309735A1,1,Brc1nccs1.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(c2nccs2)CC1 -US20060173034A1,1,COc1cc2ncc(C(N)=O)c(Cl)c2cc1OC.NC1CCc2ccccc21>>COc1cc2ncc(C(N)=O)c(NC3CCc4ccccc43)c2cc1OC -US20150232444A1,2,CC1CCN(C2CCNCC2)CC1.COc1ccc(Br)cc1S(=O)(=O)Cl>>COc1ccc(Br)cc1S(=O)(=O)N1CCC(N2CCC(C)CC2)CC1 -US08420642B2,1,O=[N+]([O-])c1ncc(Cl)cc1O.OCC1CCCC1>>O=[N+]([O-])c1ncc(Cl)cc1OCC1CCCC1 -US20150232435A1,2,CC(C)(C)c1nc(N2CCN(CCCCN)CC2)cc(C(F)(F)F)n1.O=C(O)C1CCN(Cc2ccccc2)CC1>>CC(C)(C)c1nc(N2CCN(CCCCNC(=O)C3CCN(Cc4ccccc4)CC3)CC2)cc(C(F)(F)F)n1 -US06117873,1,CCOP(=O)(CNCc1ccccc1)OCC.COc1nc2cc([N+](=O)[O-])cc(CBr)c2nc1OC>>CCOP(=O)(CN(Cc1ccccc1)Cc1cc([N+](=O)[O-])cc2nc(OC)c(OC)nc12)OCC -US20140350030A1,2,NC12CC3CC(C1)CC(C#Cc1cnccn1)(C3)C2.O=C(O)c1ccccn1>>O=C(NC12CC3CC(CC(C#Cc4cnccn4)(C3)C1)C2)c1ccccn1 -US20100016586A1,1,COc1ccc(OC)c(Sc2nc3c(N)ncnc3[nH]2)c1.FC(F)(F)c1cc(CCBr)cc(C(F)(F)F)c1>>COc1ccc(OC)c(Sc2nc3c(N)ncnc3n2CCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 -US20070049581A1,2,Nc1c(Cl)cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCC[C@@H]3C(=O)O)CC2)cc1C(F)(F)F.OCCN1CCOCC1>>Nc1c(Cl)cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCC[C@@H]3C(=O)OCCN3CCOCC3)CC2)cc1C(F)(F)F -US06051712,1,CCCC1CN(C(=O)OC(C)(C)C)CC(O)C1c1ccc(Cl)cc1.CCn1c(CCl)nc2ccccc21>>CCCC1CN(C(=O)OC(C)(C)C)CC(OCc2nc3ccccc3n2CC)C1c1ccc(Cl)cc1 -US04143154,1,O=C(O)Cc1ccc(O)cc1.O=[N+]([O-])c1oc2ccc(CBr)cc2c1-c1ccccc1>>O=C(O)Cc1ccc(OCc2ccc3oc([N+](=O)[O-])c(-c4ccccc4)c3c2)cc1 -US05889012,8,CC1(C2CCC(O)CC2)CCCCC1>>CC1(C2CCC(=O)CC2)CCCCC1 -US20110212956A1,2,CC(=O)OC(C)=O.NCCc1ccccc1Cl>>CC(=O)NCCc1ccccc1Cl -US20110130380A1,9,CC1(C)COC(CNc2nc(-c3cc(F)ncc3Cl)ccc2F)CO1.[NH4+]>>CC1(C)COC(CNc2nc(-c3cc(N)ncc3Cl)ccc2F)CO1 -US05612334,6,COC(=O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1>>O=C(O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1 -US08673942B2,9,CS(=O)(=O)c1ccc(Oc2cc(OCC3CCOCC3)c3[nH]c(C(N)=O)cc3c2)cc1>>CS(=O)(=O)c1ccc(Oc2cc(OCC3CCOCC3)c3[nH]c(C#N)cc3c2)cc1 -US20090264406A1,9,Clc1cccc(Nc2ccc3ncc(Cc4ccc5ncccc5c4)n3n2)c1>>c1ccc(Nc2ccc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1 -US20090076062A1,6,COCCCOc1cc(C[C@@H](C[C@H](N=[N+]=[N-])[C@H](C[C@H](C(=O)N[C@@H]2CCN(C)C2)C(C)C)O[Si](C)(C)C(C)(C)C)C(C)C)ccc1OC>>COCCCOc1cc(C[C@@H](C[C@H](N=[N+]=[N-])[C@@H](O)C[C@H](C(=O)N[C@@H]2CCN(C)C2)C(C)C)C(C)C)ccc1OC -US20130029980A1,1,BrCCc1ccccc1.Cc1cc(N)c([N+](=O)[O-])cc1C>>Cc1cc(NCCc2ccccc2)c([N+](=O)[O-])cc1C -US05631208,1,C=C(C)CCl.Cc1ccc(C)c(O)c1>>C=C(C)COc1cc(C)ccc1C -US07582761B2,1,C[Si](C)(C)CCOCn1c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc2cc(Br)c(C(F)(F)F)cc21.NCCc1cccc(C(F)(F)F)c1>>C[Si](C)(C)CCOCn1c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc2cc(NCCc3cccc(C(F)(F)F)c3)c(C(F)(F)F)cc21 -US20120190679A1,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)NC(CCN)c1ccc(Cl)cc1>>CC(=O)NCCC(NC(=O)OC(C)(C)C)c1ccc(Cl)cc1 -US07999006B2,1,C=O.C[C@H](N)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1>>CN[C@@H](C)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US20140288046A1,1,CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn[nH]c2n1.O=C(Cl)c1ccccc1Cl>>CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nnn(C(=O)c3ccccc3Cl)c2n1 -US04703036,2,CCN(C(=O)OCc1ccccc1)[C@H](Cc1ccccc1)C(=O)O.O=C(O)[C@@H]1CCCN1>>CCN(C(=O)OCc1ccccc1)[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O -US05272172,7,CCOC(C)O[C@@H]1OC=C(C(=O)OC)[C@H]2CC[C@H](C)[C@H]21>>CCOC(C)O[C@@H]1OC=C(CO)[C@H]2CC[C@H](C)[C@H]21 -US20060211698A1,2,CNC.COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc4nc(-c5sc(C)nc5C)ccc4c3)n(CC(=O)O)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc4nc(-c5sc(C)nc5C)ccc4c3)n(CC(=O)N(C)C)c2c1 -US20020086861A1,1,NC12CC3CC(CC(C3)C1)C2.O=S1(=O)N=C(Cl)Nc2cc(Cl)sc21>>O=S1(=O)N=C(NC23CC4CC(CC(C4)C2)C3)Nc2cc(Cl)sc21 -US20140350019A1,7,Cc1cc(-c2cc(F)cc(F)c2)cc(C(=O)Nc2c(F)ccc(O)c2F)c1C>>Cc1cc(-c2cc(F)cc(F)c2)cc(CNc2c(F)ccc(O)c2F)c1C -US05614550,2,CC(C)(C)c1ccc(CCC(=O)CC2CCCCCC2)cc1N.CCCCCCCCCCOc1ccc(C(=O)O)cc1>>CCCCCCCCCCOc1ccc(C(=O)Nc2cc(CCC(=O)CC3CCCCCC3)ccc2C(C)(C)C)cc1 -US20120107273A1,9,Cc1nc(N2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)[C@@H](C(=O)NCc3ccc(C(C)C)cc3)C2)sc1C(=O)O.N>>Cc1nc(N2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)[C@@H](C(=O)NCc3ccc(C(C)C)cc3)C2)sc1C(N)=O -US20100272680A1,6,COC(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Br>>O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Br -US20150045348A1,3,CC(OCc1ccccc1)c1nn2c(I)ncc2c(=O)[nH]1.CC1(C)OB(C2=CCOCC2)OC1(C)C>>CC(OCc1ccccc1)c1nn2c(C3=CCOCC3)ncc2c(=O)[nH]1 -US20130096149A1,4,CSc1nccc(C(Br)C(=O)c2cc(Cl)cc(NC(=O)C(C)(C)C)c2F)n1.NC(N)=S>>CSc1nccc(-c2sc(N)nc2-c2cc(Cl)cc(NC(=O)C(C)(C)C)c2F)n1 -US20130338367A1,7,O=C1C=CCCN1c1cnn(-c2cccnc2)c1>>O=C1CCCCN1c1cnn(-c2cccnc2)c1 -US20120202806A1,9,Fc1ccccc1Cc1c(Cl)nc(-c2ccccn2)nc1Cl.[NH4+]>>Nc1nc(-c2ccccn2)nc(Cl)c1Cc1ccccc1F -US06136823,1,CNN.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc([N+](=O)[O-])c(F)cc32)c(F)cc1F>>CN(N)c1cc2c(cc1[N+](=O)[O-])c(=O)c(C(=O)O)cn2-c1cc(N)c(F)cc1F -US20090098218A1,3,C#CC(C)(C)O.CC1(C)OB(c2ccc(Br)cc2)OC1(C)C>>CC(C)(O)C#Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1 -US20060063779A1,1,Cc1nc[nH]n1.N#Cc1ccc(S(=O)(=O)CCBr)cc1>>Cc1ncn(CCS(=O)(=O)c2ccc(C#N)cc2)n1 -US08202866B2,6,COC(=O)C(CC1CCN(C)CC1)c1ccc(/C=C/C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)cc1>>CN1CCC(CC(C(=O)O)c2ccc(/C=C/C(=O)Nc3ccccc3NC(=O)OC(C)(C)C)cc2)CC1 -US08293768B2,2,CCN1CCN(c2nc(C)c(C(=O)O)s2)C1=O.NCc1cccnc1>>CCN1CCN(c2nc(C)c(C(=O)NCc3cccnc3)s2)C1=O -US20040176422A1,2,CNOC.O=C(O)c1ccsc1>>CON(C)C(=O)c1ccsc1 -US20080021217A1,6,CCOC(=O)Cc1nc(-c2ccncc2)n[nH]1>>O=C(O)Cc1nc(-c2ccncc2)n[nH]1 -US20100004297A1,1,Cc1oc(-c2cccc(C(F)(F)F)c2)nc1CCl.OC(c1ccc(NCC(F)(F)F)cc1)(C(F)(F)F)C(F)(F)F>>Cc1oc(-c2cccc(C(F)(F)F)c2)nc1CN(CC(F)(F)F)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 -US08318949B2,2,Cc1nc(N2C(=O)N(Cc3ccc(F)cc3)C[C@@H]2C)sc1C(=O)O.NCc1ccccn1>>Cc1nc(N2C(=O)N(Cc3ccc(F)cc3)C[C@@H]2C)sc1C(=O)NCc1ccccn1 -US06448442B1,2,CC(=O)OCc1c(I)c(N)c(I)c(C(=O)Cl)c1I.NCCO>>CC(=O)OCc1c(I)c(N)c(I)c(C(=O)NCCO)c1I -US20150225396A1,2,N[C@@H]1CC[C@@H](Oc2ccc(Cl)cc2)CC1.O=C(O)CCCc1nc2ccccc2c(=O)[nH]1>>O=C(CCCc1nc2ccccc2c(=O)[nH]1)N[C@@H]1CC[C@@H](Oc2ccc(Cl)cc2)CC1 -US20080312208A1,1,CCOC(=O)c1cc(C#N)c(Cl)nc1N(C)C.O=C(O)C1CNC1>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1N(C)C -US20080167356A1,1,COC(=O)c1cccc2cc(-c3ccc(O)cc3)ccc12.OCc1c(-c2c(Cl)cccc2Cl)noc1C1CCC1>>COC(=O)c1cccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CCC4)cc3)ccc12 -US05308854,7,CCc1cc(C#N)c(OC)nc1C>>CCc1cc(CN)c(OC)nc1C -US04748183,1,Brc1ccsc1.COc1ccc(S)cc1>>COc1ccc(Sc2ccsc2)cc1 -US20060040986A1,1,COc1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1.COc1ccccc1-c1cc(CCl)ccn1>>COc1ccc(N(Cc2ccnc(-c3ccccc3OC)c2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US06100398,1,Cc1ccccc1Br.c1ccc(Nc2ccccc2)cc1>>Cc1ccccc1N(c1ccccc1)c1ccccc1 -US20150272947A1,1,C=O.CCOC(=O)C(C)(Cc1ccc(N2CCNCC2)cc1)C(=O)OCC>>CCOC(=O)C(C)(Cc1ccc(N2CCN(C)CC2)cc1)C(=O)OCC -US06498172B1,2,COC(=O)CCc1cccc(CNCc2ccc(-c3cncnc3)cc2)c1.O=S(=O)(Cl)c1ccccc1>>COC(=O)CCc1cccc(CN(Cc2ccc(-c3cncnc3)cc2)S(=O)(=O)c2ccccc2)c1 -US20130096118A1,1,COCCOc1ccc2c(c1)[nH]c1c(C(N)=O)ncc(-c3cccc(N)c3C)c12.Clc1ncnc2ccccc12>>COCCOc1ccc2c(c1)[nH]c1c(C(N)=O)ncc(-c3cccc(Nc4ncnc5ccccc45)c3C)c12 -US08796256B2,1,COCCBr.O=C1NC(=O)/C(=C/c2ccc3c(ccn3Cc3ccc(F)cc3C(F)(F)F)c2)S1>>COCCN1C(=O)S/C(=C\c2ccc3c(ccn3Cc3ccc(F)cc3C(F)(F)F)c2)C1=O -US05969140,1,CC1CCC(=O)N1.COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(Br)c2)c1C(=O)OC>>COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(N3C(=O)CCC3C)c2)c1C(=O)OC -US07732463B2,9,CC(C)(C)OC(=O)N1CCC(O)(c2cc(F)ccc2S)CC1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccccc2S)CC1 -US06177419B1,3,COc1cccc(-c2cccc(-c3cccc(Br)n3)n2)c1O.Cc1ccc(O)c(B(O)O)c1>>COc1cccc(-c2cccc(-c3cccc(-c4cc(C)ccc4O)n3)n2)c1O -US04051254,2,CCOCC(=O)Nc1c(C)cc(O)cc1C.CN=C=O>>CCOCC(=O)Nc1c(C)cc(OC(=O)NC)cc1C -US06339082B1,6,COC(=O)C(CNC(=O)c1cc2c(c(OC)c1OC)C1=C(CCC1)C(=NNC1=NCCN1)CC2)NC(=O)OCc1ccccc1>>COc1c(C(=O)NCC(NC(=O)OCc2ccccc2)C(=O)O)cc2c(c1OC)C1=C(CCC1)C(=NNC1=NCCN1)CC2 -US20150266822A1,6,COC(=O)c1cc(-c2ccc(C)cc2)cc(S(=O)(=O)C2CCCC2)c1>>Cc1ccc(-c2cc(C(=O)O)cc(S(=O)(=O)C3CCCC3)c2)cc1 -US08188139B2,3,CCCC[Sn](CCCC)(CCCC)c1cccc(C(F)(F)F)c1.C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1Cc2ccc(Cl)nc2C1)C(F)(F)F>>C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1Cc2ccc(-c3cccc(C(F)(F)F)c3)nc2C1)C(F)(F)F -US05250567,6,COC(=O)CS[C@@H]1CCC[C@H]1Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1>>CC(C)(C)c1cc(S[C@@H]2CCC[C@H]2SCC(=O)O)cc(C(C)(C)C)c1O -US20140243302A1,1,C1=COCCC1.CCOC(=O)CO>>CCOC(=O)COC1CCCCO1 -US20030162777A1,3,COc1cc(F)ccc1N1CCN(CC2CCc3cc(Br)ccc3N2C(=O)C2CCCCC2)CC1.Cc1noc(C)c1B(O)O>>COc1cc(F)ccc1N1CCN(CC2CCc3cc(-c4c(C)noc4C)ccc3N2C(=O)C2CCCCC2)CC1 -US20120270875A1,6,CCOC(=O)c1cnc(NCCCc2cccc(OC)c2)nc1C>>CCOC(=O)c1cnc(NCCCc2cccc(O)c2)nc1C -US08158622B2,2,CCCN.O=C(N[C@@H](Cc1ccccc1)[C@@H](O)C(=O)O)c1cc2cc(Cl)ncc2[nH]1>>CCCNC(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ncc2[nH]1 -US20060128752A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CC1(C)OC(=O)CC(=O)O1>>CC(C)(C)OC(=O)N1CCC(=C2C(=O)OC(C)(C)OC2=O)CC1 -US20120108583A1,2,Cc1cc2c(o1)c(C(=O)O)cc1nc(Nc3c(Cl)cncc3Cl)[nH]c12.NC1CCCCC1>>Cc1cc2c(o1)c(C(=O)NC1CCCCC1)cc1nc(Nc3c(Cl)cncc3Cl)[nH]c12 -US08273740B2,6,COC(=O)c1cccc(CSc2nc3ccccc3n2CC(=O)OC(C)(C)C)c1>>COC(=O)c1cccc(CSc2nc3ccccc3n2CC(=O)O)c1 -US03979396,2,CC(=O)OC(C)=O.COC(=O)C1=C(N)C(CCCCC(=O)N2CCCCC2)SC1>>COC(=O)C1=C(NC(C)=O)C(CCCCC(=O)N2CCCCC2)SC1 -US05162318,7,COC(=O)c1ccc2c(c1)[nH]c(=O)n2CCN(C)C>>CN(C)CCn1c(=O)[nH]c2cc(CO)ccc21 -US20040143001A1,1,CCCCCCCCBr.Oc1ccc(-c2c3nc(c(-c4ccc(O)cc4)c4ccc([nH]4)c(-c4ccc(O)cc4)c4nc(c(-c5ccc(O)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1>>CCCCCCCCOc1ccc(-c2c3nc(c(-c4ccc(O)cc4)c4ccc([nH]4)c(-c4ccc(O)cc4)c4nc(c(-c5ccc(O)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1 -US04062798,6,CCCCCCc1ccc(-c2ccc(-c3ncc(C(=O)OCC)cn3)cc2)cc1>>CCCCCCc1ccc(-c2ccc(-c3ncc(C(=O)O)cn3)cc2)cc1 -US20100197908A1,3,C#Cc1ccc(C=O)cc1.Ic1ccc(C#Cc2ccsc2)nn1>>O=Cc1ccc(C#Cc2ccc(C#Cc3ccsc3)nn2)cc1 -US08258134B2,6,COC(=O)C(CC1CCCC1)n1ncccc1=O>>O=C(O)C(CC1CCCC1)n1ncccc1=O -US20050234029A1,1,C1COCCN1.Cc1ccn2c(-c3ccnc(-c4ccc(C=O)cc4)c3)c(-c3cccc(C)n3)nc2c1>>Cc1ccn2c(-c3ccnc(-c4ccc(CN5CCOCC5)cc4)c3)c(-c3cccc(C)n3)nc2c1 -US20050043336A1,1,Cc1cc(Nc2ncnc3cccc(OC4CCN(C)CC4)c23)ccc1O.N#Cc1ccccc1CCl>>Cc1cc(Nc2ncnc3cccc(OC4CCN(C)CC4)c23)ccc1OCc1ccccc1C#N -US20050107616A1,3,CC(C)(C)[Mg+].O=Cc1cccc(Br)c1>>CC(C)(C)C(O)c1cccc(Br)c1 -US04529438,1,COC(=O)C(C)Br.Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1>>COC(=O)C(C)Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1 -US07320992B2,9,CC(C)(C)c1ccc(N2C(=O)c3c(ccnc3F)C2O)cc1>>CC(C)(C)c1ccc(N2Cc3ccnc(F)c3C2=O)cc1 -US20120190677A1,6,COC(=O)c1cc(F)cc2c1NC(c1cccc(N3CCN(c4ccc(C)cc4)CC3)c1)CC2(C)C>>Cc1ccc(N2CCN(c3cccc(C4CC(C)(C)c5cc(F)cc(C(=O)O)c5N4)c3)CC2)cc1 -US07132436B2,2,CCCc1ccc(S(=O)(=O)Cl)cc1.CS(=O)(=O)c1sc(Cl)c2c1-c1nc(N)sc1CC2>>CCCc1ccc(S(=O)(=O)Nc2nc3c(s2)CCc2c(Cl)sc(S(C)(=O)=O)c2-3)cc1 -US20050277643A1,1,Cc1cccc(Br)c1.c1nc2c(c(Nc3ccc4c(c3)OCCO4)n1)CCNC2>>Cc1cccc(N2CCc3c(ncnc3Nc3ccc4c(c3)OCCO4)C2)c1 -US20110071147A1,7,CC1(C)OCC(COCCC#N)O1>>CC1(C)OCC(COCCCN)O1 -US20120220633A1,1,COc1ccc(N)cc1.O=[N+]([O-])c1ccccc1F>>COc1ccc(Nc2ccccc2[N+](=O)[O-])cc1 -US20150183801A1,3,Cc1ccc(B(O)O)cn1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCC[C@@H](O)C2)c(Br)c1>>Cc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N2CCC[C@@H](O)C2)cn1 -US06884774B2,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCC2(CC1)OCCO2>>C=C1CCC2(CC1)OCCO2 -US08598208B2,6,CCOC(=O)c1cc(C)c(CC(C)C)cn1>>Cc1cc(C(=O)O)ncc1CC(C)C -US06147115,2,NS(=O)(=O)C1CCCC1.O=C=Nc1ccc(Br)cc1>>O=C(Nc1ccc(Br)cc1)NS(=O)(=O)C1CCCC1 -US04242265,2,CC(=O)SCCC(=O)O.O=C(O)CO>>CC(=O)SCCC(=O)OC(=O)CO -US20140073634A1,1,CN1CCNCC1.Cc1ccc(-c2nnc(-c3ccc(OC(F)(F)F)cc3)o2)c(=O)n1Cc1ccnc(Cl)c1>>Cc1ccc(-c2nnc(-c3ccc(OC(F)(F)F)cc3)o2)c(=O)n1Cc1ccnc(N2CCN(C)CC2)c1 -US20060116386A1,3,CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C.Cc1cn(-c2ccc(Br)c(C)n2)nn1>>Cc1cn(-c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)c(C)n2)nn1 -US06331637B1,2,Cc1noc(N)c1Br.O=S(=O)(Cl)c1c(Cc2ccccc2)sc2ccccc12>>Cc1noc(NS(=O)(=O)c2c(Cc3ccccc3)sc3ccccc23)c1Br -US07192950B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(CC2NCCSc3cc(OC)c(OC)cc32)cc1OC>>COc1ccc(CC2c3cc(OC)c(OC)cc3SCCN2C(=O)OC(C)(C)C)cc1OC -US05242890,9,CCC(=O)c1noc(COc2ccc(Cl)cc2Cl)n1.NO>>CCC(=NO)c1noc(COc2ccc(Cl)cc2Cl)n1 -US08962859B2,1,C1COCCN1.CC(C)(C)OC(=O)NC1=NC2(c3cc(-c4cccnc4F)ccc3Oc3c(F)cc(OS(=O)(=O)C(F)(F)F)cc32)c2nccn21>>CC(C)(C)OC(=O)NC1=NC2(c3cc(-c4cccnc4F)ccc3Oc3c(F)cc(N4CCOCC4)cc32)c2nccn21 -US08232294B2,6,COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)OC(=O)CNC(=O)OC(C)(C)C)n(-c5ccccc5)c4=O)nc3)ccnc2c1>>COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)OC(=O)CN)n(-c5ccccc5)c4=O)nc3)ccnc2c1 -US20040266839A1,2,Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)O)cc3)c2)o1.NCc1ccc(Cl)cc1>>Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCc4ccc(Cl)cc4)cc3)c2)o1 -US08110687B2,6,CC(C)(C)OC(=O)Nc1cc(C#N)cc(C(C)(C)C)c1>>CC(C)(C)c1cc(N)cc(C#N)c1 -US20120277220A1,7,COc1cc(CCN2CCCC2)ccc1[N+](=O)[O-]>>COc1cc(CCN2CCCC2)ccc1N -US08609848B2,2,CN(C)c1ccc(C(=O)O)c2ccccc12.COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)c4ccc(N(C)C)c5ccccc45)CC3)C(=O)C2(C)C)cc1OC -US20110313151A1,2,N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1.O=C(O)c1ccc(N2CCOCC2)cc1>>O=C(N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1)c1ccc(N2CCOCC2)cc1 -US20150239833A1,2,CO.COc1ccc(S(=O)Cl)cc1OC>>COc1ccc(S(=O)OC)cc1OC -US07067534B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.Cc1ccccc1N=C=S>>Cc1ccccc1NC(=S)N[C@@H](CCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)c1ccccc1 -US20090192147A1,8,COc1ccc2c(c1)cc(CO)n2CCCl>>COc1ccc2c(c1)cc(C=O)n2CCCl -US20030153558A1,9,OCc1c(-c2ccncc2)c(-c2ccc(F)cc2)n2c1SCC2>>Cc1c(-c2ccncc2)c(-c2ccc(F)cc2)n2c1SCC2 -US20120225857A1,3,CN(C)C(C)(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Nc1ncc(Br)cc1-c1ccc2c(c1)CCNC2=O>>CN(C)C(C)(C)c1ccc(-c2cnc(N)c(-c3ccc4c(c3)CCNC4=O)c2)cc1 -US20050267095A1,2,CN.O=C(O)C1(c2ccc(OCCCN3CCOCC3)cc2)CCOCC1>>CNC(=O)C1(c2ccc(OCCCN3CCOCC3)cc2)CCOCC1 -US07595320B2,6,CN(NC(=O)c1cc2c(NC(=O)c3cccc(CN4CCOCC4)c3)nn(C(=O)OC(C)(C)C)c2s1)c1ccccc1>>CN(NC(=O)c1cc2c(NC(=O)c3cccc(CN4CCOCC4)c3)n[nH]c2s1)c1ccccc1 -US20040029873A1,2,NC(=O)c1ccccc1N.O=C(Cl)C1CCCCC1>>NC(=O)c1ccccc1NC(=O)C1CCCCC1 -US04125614,2,CC(=O)c1ccc(Cl)c(S(=O)(=O)Cl)c1.CNC>>CC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 -US20080200540A1,1,C=CC(C)O.N#Cc1ccc(O)c(Cl)c1>>C=CC(C)Oc1ccc(C#N)cc1Cl -US20130158075A1,2,COC(=O)C1CCC(c2ncc(-c3ccc(N)cc3)s2)CC1.O=C=Nc1ccc(Cl)cc1Oc1ccccc1>>COC(=O)C1CCC(c2ncc(-c3ccc(NC(=O)Nc4ccc(Cl)cc4Oc4ccccc4)cc3)s2)CC1 -US07005431B2,3,CC(C)(O)c1cnn2c(Br)cnc2n1.COc1cc(F)ccc1B1OC(C)(C)C(C)(C)O1>>COc1cc(F)ccc1-c1cnc2nc(C(C)(C)O)cnn12 -US20100267666A1,2,CC(C)(C)C(=O)c1c[nH]c2ncc(-c3cccc(N)c3)nc12.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)C(=O)c1c[nH]c2ncc(-c3cccc(NS(=O)(=O)c4ccccc4)c3)nc12 -US04414219,2,CN1CCC(O)(c2ccccc2Cc2ccccc2)CC1.O=C(Cl)c1ccccc1>>CN1CCC(OC(=O)c2ccccc2)(c2ccccc2Cc2ccccc2)CC1 -US20090012087A1,6,CC(C)(C)OC(=O)N1[C@H](C(=O)NCc2cc(Cl)ccc2-n2cnnn2)C[C@@H]2C[C@@H]21>>O=C(NCc1cc(Cl)ccc1-n1cnnn1)[C@@H]1C[C@@H]2C[C@@H]2N1 -US20060025474A1,3,C=CC(=O)CC.CCC(CC)(c1ccc(O)cc1)c1ccc(Br)c(C)c1>>CCC(=O)/C=C/c1ccc(C(CC)(CC)c2ccc(O)cc2)cc1C -US04438035,1,CN(C)CCCl.COc1ccc([C@@H]2Sc3ccccc3NC(=O)[C@@H]2O)cc1>>COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2O)cc1 -US20100286117A1,6,CCCCc1noc(C)c1CNc1ccc(C(=O)OC)cn1>>CCCCc1noc(C)c1CNc1ccc(C(=O)O)cn1 -US06881844B2,2,CC(C)n1cc(C(=O)O)c2ccc(Cl)cc21.Cc1cnc(N)s1>>Cc1cnc(NC(=O)c2cn(C(C)C)c3cc(Cl)ccc23)s1 -US20090042841A1,3,C#Cc1ccccc1.CC(C)(C)OC(=O)N1CCC(=C(F)Br)CC1>>CC(C)(C)OC(=O)N1CCC(=C(F)C#Cc2ccccc2)CC1 -US20130245072A1,6,COC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2nc(C)oc12>>Cc1nc2c(C3=NOC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)ccc(C(=O)O)c2o1 -US04372962,1,CCOC(CBr)OCC.NC(=O)CS>>CCOC(CSCC(N)=O)OCC -US20040110951A1,6,COc1ccc(Oc2c(C)cc(-c3n[nH]c(=O)[nH]3)cc2C)cc1C(C)C>>Cc1cc(-c2n[nH]c(=O)[nH]2)cc(C)c1Oc1ccc(O)c(C(C)C)c1 -US07879907B2,6,CCCCOc1cc(CCC(=O)OC)ccc1CCCc1ccc(OCCCC)c(OC)c1>>CCCCOc1cc(CCC(=O)O)ccc1CCCc1ccc(OCCCC)c(OC)c1 -US20080176830A1,3,O=C1CCc2cc(Br)cnc2N1.OB(O)c1ccc(C(F)(F)F)cc1>>O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)cnc2N1 -US20110015177A1,2,COc1cc(F)ccc1C(=O)O.NC1COCCn2c1nc(-c1ccncc1)cc2=O>>COc1cc(F)ccc1C(=O)NC1COCCn2c1nc(-c1ccncc1)cc2=O -US20080119555A1,3,O=S(=O)(NCCCCO)c1ccc(Br)cc1C(F)(F)F.OB(O)c1ccccc1>>O=S(=O)(NCCCCO)c1ccc(-c2ccccc2)cc1C(F)(F)F -US08148380B2,9,Cc1noc(C)c1C(=O)N(C)Cc1nc(NC(=O)NCc2cccc(F)c2)sc1Br.N#C[Cu]>>Cc1noc(C)c1C(=O)N(C)Cc1nc(NC(=O)NCc2cccc(F)c2)sc1C#N -US20070232601A1,6,COC(=O)Cc1cc(Cl)c(Nc2nc3cc(F)ccc3s2)cc1F>>O=C(O)Cc1cc(Cl)c(Nc2nc3cc(F)ccc3s2)cc1F -US07649001B2,9,C[C@H]1[C@@H](C(N)=O)CCN1c1ccc(C#N)c2ccccc12>>C[C@H]1[C@@H](C#N)CCN1c1ccc(C#N)c2ccccc12 -US07521470B2,3,O=C(NCC1CC(c2ccc(Br)cc2)=NO1)c1ccc(Cl)s1.O=Cc1ccccc1B(O)O>>O=Cc1ccccc1-c1ccc(C2=NOC(CNC(=O)c3ccc(Cl)s3)C2)cc1 -US05770617,7,Nc1cc(Cl)ccc1[N+](=O)[O-]>>Nc1ccc(Cl)cc1N -US05804103,2,O=C(O)c1cccc(O)c1.OCCCl>>O=C(OCCCl)c1cccc(O)c1 -US20050101063A1,7,C[Si](C)(C)C#Cc1ccc(-c2ccc(C#C[Si](C)(C)C)cc2[N+](=O)[O-])c([N+](=O)[O-])c1>>C[Si](C)(C)C#Cc1ccc(-c2ccc(C#C[Si](C)(C)C)cc2[N+](=O)[O-])c(N)c1 -US04550182,3,CC(C)CCCC(C)CCCC(C)CCl.Cc1c(C)c2c(c(C)c1O)CCC(C)(CCBr)O2>>Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2 -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNC(CCC(=O)OC(C)(C)C)C2)nc1C(F)(F)F.O=C=Nc1ccc(Cl)s1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)Nc3ccc(Cl)s3)C(CCC(=O)OC(C)(C)C)C2)nc1C(F)(F)F -US20110105544A1,6,COc1ccc(CCCC(=O)O)cc1>>O=C(O)CCCc1ccc(O)cc1 -US20070249670A1,7,COC(=O)[C@@H](NC(=O)c1ccc(F)cc1[N+](=O)[O-])C1CCCCC1>>COC(=O)[C@@H](NC(=O)c1ccc(F)cc1N)C1CCCCC1 -US20100113465A1,9,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCC2(CC1)CC(O)C2>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(Br)C2 -US20100019229A1,3,CCCC[Sn](CCCC)(CCCC)c1scc(P(=O)(OCC)OCC)c1P(=O)(OCC)OCC.CCOP(=O)(OCC)c1csc(I)c1P(=O)(OCC)OCC>>CCOP(=O)(OCC)c1csc(-c2scc(P(=O)(OCC)OCC)c2P(=O)(OCC)OCC)c1P(=O)(OCC)OCC -US20040054179A1,1,COc1ccc(-c2cc3nccn3c(Cl)n2)cc1OC.Fc1ccc(N2CCNCC2)cc1>>COc1ccc(-c2cc3nccn3c(N3CCN(c4ccc(F)cc4)CC3)n2)cc1OC -US20020161237A1,2,COC(=O)C(N)P(=O)(OC)OC.O=C(NCc1cccc(O)c1)c1ccc(C(=O)O)c(Br)c1>>COC(=O)C(NC(=O)c1ccc(C(=O)NCc2cccc(O)c2)cc1Br)P(=O)(OC)OC -US20150197503A1,9,CC(=O)c1cccnc1.NO>>CC(=NO)c1cccnc1 -US20020198196A1,1,CC1=C(c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)cc2C)CCC[C@H]1O.CI>>CO[C@@H]1CCCC(c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)cc2C)=C1C -US04483987,2,CC(C)(C)C(=O)Cl.Nc1nc(-c2ccccc2)c(CCO)c2ncnn12>>CC(C)(C)C(=O)OCCc1c(-c2ccccc2)nc(N)n2ncnc12 -US20070185155A1,1,Fc1ccc(OCCCBr)cc1.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCOc3ccc(F)cc3)(CC1)CC2 -US08993586B2,1,CCOC(=O)c1ccc2ccnc(Cl)c2c1.CN>>CCOC(=O)c1ccc2ccnc(NC)c2c1 -US20040186301A1,6,CCOC(=O)CC(CC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CCOC(=O)CC(CC(=O)OC(C)(C)C)C(=O)O -US20050026935A1,1,Clc1nc(NCc2ccccn2)c2c(-c3ccccc3)csc2n1.NCC1CC1>>c1ccc(-c2csc3nc(NCC4CC4)nc(NCc4ccccn4)c23)cc1 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2ccc(C3CC3)nc2)c1.CC(C)(C)OC(=O)Nc1ccc(OC(F)(F)F)cc1N>>CC(C)(C)OC(=O)Nc1ccc(OC(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2ccc(C3CC3)nc2)c1 -US20110301353A1,3,CN(C)C=O.Cc1c[nH]c2c1C(=O)N(CCN1CCOCC1)CC2>>Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCOCC1)CC2 -US20070244117A1,2,CC(=O)OCC(=O)Cl.Nc1cc(Cn2c(=O)oc(=O)c3ccccc32)ccn1>>CC(=O)OCC(=O)Nc1cc(Cn2c(=O)oc(=O)c3ccccc32)ccn1 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2ccc(F)cc2)cc1.O=C(O)c1c(F)ccc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccc(F)cc2)C(=O)c2c(F)ccc3cc[nH]c23)cc1 -US20090264650A1,5,COCCl.Cc1ccc(O)cc1Cl>>COCOc1ccc(C)c(Cl)c1 -US06911468B2,1,CCCCCCCCCCOc1cccc(-n2c(C)ccc2-c2ccc(O)cc2)c1.CCOC(=O)[C@@H](O)Cc1ccccc1>>CCCCCCCCCCOc1cccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)c1 -US20110288085A1,3,Nc1ncc(Br)cc1Br.OB(O)c1ccc(F)cc1F>>Nc1ncc(Br)cc1-c1ccc(F)cc1F -US20080004321A1,6,CCCc1c(OCc2cccc(C(=O)Nc3cccc(C(=O)OC)c3)c2)ccc(C(C)=O)c1O>>CCCc1c(OCc2cccc(C(=O)Nc3cccc(C(=O)O)c3)c2)ccc(C(C)=O)c1O -US05834493,7,O=C(CCCCl)c1ccc(F)cc1>>Fc1ccc(CCCCCl)cc1 -US06838463B2,1,C[C@H]1CC[C@H](O)CC1.Clc1cc(Cl)ncn1>>C[C@@H]1CC[C@@H](Oc2cc(Cl)ncn2)CC1 -US20090042874A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(c2)NC(=O)CO3)CC1.CI>>CN1C(=O)COc2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)cc21 -US08987251B2,6,Cc1ccn2c(-c3ccc4cccc(O[Si](C)(C)C(C)(C)C)c4n3)nnc2c1>>Cc1ccn2c(-c3ccc4cccc(O)c4n3)nnc2c1 -US20150203487A1,1,CS(=O)(=O)c1nc2nc(-c3ccc(-c4ccc(C(=O)N5CC[C@@H](O)C5)cc4)cc3)c(Cl)cc2[nH]1.C[Si](C)(C)CCOCCl>>C[Si](C)(C)CCOCn1c(S(C)(=O)=O)nc2nc(-c3ccc(-c4ccc(C(=O)N5CC[C@@H](O)C5)cc4)cc3)c(Cl)cc21 -US20070197604A1,1,CCNCC.Cc1oc(-c2ccc(Br)cc2)nc1CCOS(C)(=O)=O>>CCN(CC)CCc1nc(-c2ccc(Br)cc2)oc1C -US20150166558A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C(N)c1cccc([N+](=O)[O-])c1>>COC(=O)C(NC(=O)OC(C)(C)C)c1cccc([N+](=O)[O-])c1 -US06245761B1,1,CC(C)N.Fc1ccc(Br)cc1COCC#CCBr>>CC(C)NCC#CCOCc1cc(Br)ccc1F -US08318949B2,2,Cc1nc(N2C[C@H](C)N(Cc3ccc(F)cc3)C2=O)sc1C(=O)O.NCc1ccc(F)c(F)c1>>Cc1nc(N2C[C@H](C)N(Cc3ccc(F)cc3)C2=O)sc1C(=O)NCc1ccc(F)c(F)c1 -US20140296261A1,3,CC1(C)OB(c2cccnc2F)OC1(C)C.Clc1ncnc2[nH]ccc12>>Fc1ncccc1-c1ncnc2[nH]ccc12 -US07368579B2,9,O=[N+]([O-])c1nc(Cl)[nH]c1I>>O=[N+]([O-])c1c[nH]c(Cl)n1 -US20050222213A1,1,C[O-].O=[N+]([O-])c1ccc(F)c(C(F)(F)F)c1>>COc1ccc([N+](=O)[O-])cc1C(F)(F)F -US08569535B2,7,CC(C)=Cc1c(C)cccc1C(=O)NC1(C(=O)O)Cc2ccccc2C1>>Cc1cccc(C(=O)NC2(C(=O)O)Cc3ccccc3C2)c1CC(C)C -US08367713B2,4,C#CCc1c[nH]c(N)n1.Cc1cc2nc(CN=[N+]=[N-])[nH]c2cc1C>>Cc1cc2nc(Cn3cc(Cc4c[nH]c(N)n4)nn3)[nH]c2cc1C -US20100041676A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.COc1cc(-n2nc(I)c3ncnc(N)c32)ccc1[N+](=O)[O-]>>COc1cc(-n2nc(C3=CCN(C(=O)OC(C)(C)C)CC3)c3ncnc(N)c32)ccc1[N+](=O)[O-] -US20090312338A1,2,O=S(=O)(Cl)C1CC1.c1cc2c(ncc3[nH]nc(C4CCNCC4)c32)[nH]1>>O=S(=O)(C1CC1)N1CCC(c2n[nH]c3cnc4[nH]ccc4c23)CC1 -US07605176B2,7,COC(=O)c1cc([N+](=O)[O-])ccc1OCCN1CCCC1>>COC(=O)c1cc(N)ccc1OCCN1CCCC1 -US07659297B2,8,COc1c(C(C)(C)CC(O)(CO)C(F)(F)F)ccc(C)c1F>>COc1c(C(C)(C)CC(O)(C=O)C(F)(F)F)ccc(C)c1F -US09120788B2,4,Nc1cccnc1Nc1ccc(Cl)c(F)c1.O=C(O)C(=O)NC1CC1>>O=C(NC1CC1)c1nc2cccnc2n1-c1ccc(Cl)c(F)c1 -US20050176775A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc2c(c1)CNC2>>COC(=O)c1ccc2c(c1)CN(C(=O)OC(C)(C)C)C2 -US05691349,1,C=CCBr.N#Cc1ccc(O)cc1>>C=CCOc1ccc(C#N)cc1 -US04985446,1,CC(C)(C)c1ccc(OC[C@@H]2CNCC[C@H]2c2ccc(F)cc2)cc1.CCCBr>>CCCN1CC[C@@H](c2ccc(F)cc2)[C@H](COc2ccc(C(C)(C)C)cc2)C1 -US20140057902A1,6,CC(C)(C)OC(=O)NCC(=O)N1CCc2c(Br)cccc2C1CC(=O)O>>[NH3+]CC(=O)N1CCc2c(Br)cccc2C1CC(=O)O -US06252086B1,3,C#CCO.COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(I)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(C#CCO)c21 -US07067534B1,1,Ic1cccnc1.c1ccc2[nH]ccc2c1>>c1cncc(-n2ccc3ccccc32)c1 -US07608731B2,1,CC(C)(C)NC(=O)c1cc([O-])cc(C(=O)NC(C)(C)C)c1.O=[N+]([O-])c1ccc(F)c(F)c1F>>CC(C)(C)NC(=O)c1cc(Oc2c([N+](=O)[O-])ccc(F)c2F)cc(C(=O)NC(C)(C)C)c1 -US20090163488A1,2,Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(N)cn4c3)ccc2F)n(C)n1.O=C(Cl)C1CC1>>Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)ccc2F)n(C)n1 -US20100216788A1,2,CC(C)(O)CC(=O)O.NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(-c5nc(C(F)(F)F)cs5)c4)c(Cl)c3)c21>>CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(-c5nc(C(F)(F)F)cs5)c4)c(Cl)c3)c21 -US20100197681A1,2,CC(=O)N1CCC(C(=O)Cl)CC1.Nc1nc2cccc(-c3ccoc3)n2n1>>CC(=O)N1CCC(C(=O)Nc2nc3cccc(-c4ccoc4)n3n2)CC1 -US06545009B1,4,COC(=O)c1cccc(C(N)=S)c1.O=C(CBr)c1ccc(C(F)(F)F)cc1>>COC(=O)c1cccc(-c2nc(-c3ccc(C(F)(F)F)cc3)cs2)c1 -US20090264466A1,6,COC(=O)C1(C(=O)OC)CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(C(=O)O)CCN(C(=O)OC(C)(C)C)CC1 -US20050096380A1,8,CCOc1c(/C(C)=C(/F)CO)cc2c(c1Br)C(C)(C)CC=C2C(C)C>>CCOc1c(/C(C)=C(/F)C=O)cc2c(c1Br)C(C)(C)CC=C2C(C)C -US20120289520A1,2,CCOC(=O)C1CCNCC1.Cc1nc(C)c(-c2ccc(-c3ccc(CC(=O)O)cc3Cl)cc2)nc1C(N)=O>>CCOC(=O)C1CCN(C(=O)Cc2ccc(-c3ccc(-c4nc(C(N)=O)c(C)nc4C)cc3)c(Cl)c2)CC1 -US20150218092A1,7,Cc1cc([N+](=O)[O-])ccc1OCCN1CCCC1>>Cc1cc(N)ccc1OCCN1CCCC1 -US20150126513A1,10,Cc1cccc(Cl)c1C#N.O=C1CCC(=O)N1Br>>N#Cc1c(Cl)cccc1CBr -US07015218B1,2,Cc1c(C(=O)O)cnn1-c1ccc(F)cc1F.N#Cc1cc(N)ccc1N1CCN(CCO)CC1>>Cc1c(C(=O)Nc2ccc(N3CCN(CCO)CC3)c(C#N)c2)cnn1-c1ccc(F)cc1F -US05539112,6,CC(=O)N(CCCN1C(=O)c2ccccc2C1=O)c1ccc(-c2cc(=O)c3c(N)ccc(F)c3o2)cc1>>Nc1ccc(F)c2oc(-c3ccc(NCCCN4C(=O)c5ccccc5C4=O)cc3)cc(=O)c12 -US07259163B2,6,COc1cc(C(=O)N2[C@@H](c3cccs3)[C@@H](c3cnccn3)C[C@@]2(CC(C)C)C(=O)OC(C)(C)C)ccc1C(C)(C)C>>COc1cc(C(=O)N2[C@@H](c3cccs3)[C@@H](c3cnccn3)C[C@@]2(CC(C)C)C(=O)O)ccc1C(C)(C)C -US07504408B2,1,CN1CCNCC1.COCCC#Cc1cc(Cl)c(Nc2ncnc3cc(OCCCCl)c(OC)cc23)c2c1OCO2>>COCCC#Cc1cc(Cl)c(Nc2ncnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c2c1OCO2 -US05242914,1,C=O.CCNC(=O)[C@@H]1C[C@H](SCc2ccc(OC)cc2)CN1>>CCNC(=O)[C@@H]1C[C@H](SCc2ccc(OC)cc2)CN1C -US20070185089A1,6,CC(C)(C)OC(=O)c1ccc(N2CCC(c3ccc4c(c3)CCN(C3CCC3)CC4)CC2)cn1>>O=C(O)c1ccc(N2CCC(c3ccc4c(c3)CCN(C3CCC3)CC4)CC2)cn1 -US08247403B2,6,CC(C)(C)OC(=O)N1CCOc2c(cccc2-c2ccccc2F)C1>>Fc1ccccc1-c1cccc2c1OCCNC2 -US05877193,4,N#Cc1cccc(C(=O)CBr)c1.NC(N)=S>>N#Cc1cccc(-c2csc(N)n2)c1 -US07468391B2,6,CC(C)OC(=O)c1cccc(C#C[Si](C)(C)C)c1>>C#Cc1cccc(C(=O)OC(C)C)c1 -US06919404B2,1,CCCNCCC.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>CCCN(CCC)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-] -US07915274B2,1,COc1nccnc1C=O.O=C(CC1CCNCC1)c1ccccc1F>>COc1nccnc1CN1CCC(CC(=O)c2ccccc2F)CC1 -US20150045409A1,2,CCCCCC/C=C/C(=O)O.NCC1CCCCO1>>CCCCCC/C=C/C(=O)NCC1CCCCO1 -US05719291,4,CCCCCCC/C=C/[C@@H]1OC[C@H](C)[C@H](OC)C1=O.C[S+](C)(C)=O>>CCCCCCC/C=C/[C@@H]1OC[C@H](C)[C@H](OC)[C@@]12CO2 -US20090221555A1,1,CS(=O)(=O)Nc1ccccc1Nc1nc(Cl)ncc1Cl.Nc1ccc2c(c1)CNC(=O)NC2>>CS(=O)(=O)Nc1ccccc1Nc1nc(Nc2ccc3c(c2)CNC(=O)NC3)ncc1Cl -US20130150326A1,4,CCOC(=O)c1cccc(SCC(C)=O)c1.Cc1c(Cl)cccc1NN>>CCOC(=O)c1cccc(Sc2c(C)[nH]c3c(C)c(Cl)ccc23)c1 -US05047555,2,COc1ccc(OC)c(C=CC(=O)O)c1.Cc1cc(N)cc(C)c1O>>COc1ccc(OC)c(C=CC(=O)Nc2cc(C)c(O)c(C)c2)c1 -US20030199511A1,3,CC(C)(C)C(=O)Nc1ccncc1.CN(C)C=O>>CC(C)(C)C(=O)Nc1ccncc1C=O -US08445692B2,1,CC(C)(C)[Si](C)(C)Oc1cc(C=O)cc(O[Si](C)(C)C(C)(C)C)c1.CCOC(=O)C(C)(C)N>>CCOC(=O)C(C)(C)NCc1cc(O[Si](C)(C)C(C)(C)C)cc(O[Si](C)(C)C(C)(C)C)c1 -US08524718B2,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.COc1ccc(CCl)cc1>>COc1ccc(Cn2cc(B3OC(C)(C)C(C)(C)O3)cn2)cc1 -US08202984B2,3,Clc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(Br)s1.N#Cc1cccc(B(O)O)c1>>N#Cc1cccc(-c2ccc(Cc3cc([C@@H]4O[C@H](COCc5ccccc5)[C@@H](OCc5ccccc5)[C@H](OCc5ccccc5)[C@H]4OCc4ccccc4)ccc3Cl)s2)c1 -US09051311B2,3,CC(C)(C)OC(=O)N1CC=C(c2cc(C(F)(F)F)ccc2Br)CC1.OB(O)c1cccc2cnccc12>>CC(C)(C)OC(=O)N1CC=C(c2cc(C(F)(F)F)ccc2-c2cccc3cnccc23)CC1 -US04329518,7,CC1=CC(=O)CC(c2ccccc2F)C1>>CC1=CC(O)CC(c2ccccc2F)C1 -US06395732B1,1,Cc1c(SCCCCl)ccnc1CCl.Nc1ncncc1Cl>>Cc1c(SCCCCl)ccnc1CNc1ncncc1Cl -US20100317739A1,2,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.NCCCCCC(=O)O>>CN(C)c1cccc2c(S(=O)(=O)NCCCCCC(=O)O)cccc12 -US05015260,7,COc1cc(C)c(OC(C)=O)cc1NC(C)=O>>COc1cc(C)c(O)cc1NC(C)=O -US20140128385A1,2,COC(=O)C(C)(N)c1cc(Br)ccc1F.O=C(Cl)CCl>>COC(=O)C(C)(NC(=O)CCl)c1cc(Br)ccc1F -US20030229251A1,7,CCCCCCCCc1ccc(C(=O)CBr)cc1>>CCCCCCCCc1ccc(CCBr)cc1 -US07659279B2,2,COc1cc(OC[C@@H]2C[C@H](O)CN2)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1.O=C(O)CO>>COc1cc(OC[C@@H]2C[C@H](O)CN2C(=O)CO)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1 -US20150266878A1,3,NC(=O)C(Nc1cncc(Br)c1)c1ccccc1.O=C1CCc2cc(Br)c(F)cc2N1>>NC(=O)C(Nc1cncc(-c2cc3c(cc2F)NC(=O)CC3)c1)c1ccccc1 -US20020052376A1,6,COC(=O)c1ccc(OC)cc1-c1ccc(F)cc1>>COc1ccc(C(=O)O)c(-c2ccc(F)cc2)c1 -US20090143385A1,2,CCN.CCOC(=O)c1ccc(OCc2c(-c3cccc(F)c3)noc2C)nn1>>CCNC(=O)c1ccc(OCc2c(-c3cccc(F)c3)noc2C)nn1 -US20040138230A1,2,CC(C)=CC(=O)Cl.c1ccc2c(c1)CCCN2>>CC(C)=CC(=O)N1CCCc2ccccc21 -US20050182040A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Oc2ccc(C(N)=O)c(F)c2)CC1>>NC(=O)c1ccc(O[C@@H]2CC[C@@H](N)CC2)cc1F -US20080188473A1,3,CCOC(=O)c1cc2cc(Br)ccc2[nH]1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2[nH]1 -US20080306046A1,2,CC(C)(C)OC(=O)N1CCC(CCc2cccc(C(=O)O)c2)CC1.NCCBr>>CC(C)(C)OC(=O)N1CCC(CCc2cccc(C(=O)NCCBr)c2)CC1 -US05593984,9,Cc1nccn2c(Br)ccc12.N#C[Cu]>>Cc1nccn2c(C#N)ccc12 -US05179125,6,CCOC(=O)c1cccc(NC(=O)C(CSC(C)=O)Cc2ccccc2)c1>>CCOC(=O)c1cccc(NC(=O)C(CS)Cc2ccccc2)c1 -US05128448,2,O=C(Cl)CCC1CCCC1.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(CCC1CCCC1)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20150258074A1,1,COC(=O)c1cc2[nH]nc(Br)c2cn1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)c1cc2c(cn1)c(Br)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20080255155A1,7,O=[N+]([O-])c1ccc(Oc2ccnc(Cl)n2)c(F)c1>>Nc1ccc(Oc2ccnc(Cl)n2)c(F)c1 -US07923573B2,1,C=CCOC(=O)Cc1ccc(-c2ccc(O)c(F)c2)cc1.COCOc1c(C(F)(F)F)ccc(CO)c1C(OC)OC>>C=CCOC(=O)Cc1ccc(-c2ccc(OCc3ccc(C(F)(F)F)c(OCOC)c3C(OC)OC)c(F)c2)cc1 -US20060089375A1,6,CC(=O)NCc1cccc(CNC(=O)OC(C)(C)C)c1>>CC(=O)NCc1cccc(CN)c1 -US05733913,2,CC(C)(C)N=C=O.Cc1ccccc1-c1cc2cnc(N)nc2nc1N>>Cc1ccccc1-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C -US04064236,2,CC(=O)N[C@@H](C)C(=O)O.CC(C)C[C@H](NC(=O)[C@H](C)N)C(=O)OCc1ccccc1>>CC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1 -US04931452,6,COc1ncc(OC(F)(F)C(F)F)cc1F>>Oc1ncc(OC(F)(F)C(F)F)cc1F -US05556864,6,COCOc1cccc(CCc2ccccc2OCCC2CCN(C)CC2)c1>>CN1CCC(CCOc2ccccc2CCc2cccc(O)c2)CC1 -US08324249B2,1,O=C(NC1CC1)c1cccc(C2=CCNCC2)n1.O=Cc1cc(C(F)(F)F)no1>>O=C(NC1CC1)c1cccc(C2=CCN(Cc3cc(C(F)(F)F)no3)CC2)n1 -US20050148640A1,5,N#Cc1nonc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>N#Cc1nonc1NC(=O)C(F)(F)F -US05541229,6,CCCCc1nc2ccc(C(=O)OCC)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2ccc(C(=O)OCC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20080269210A1,3,CS(=O)(=O)c1ccc(C(=O)c2cc3nc(Cl)nc(N4CCOCC4)c3s2)cc1.Nc1ncc(B(O)O)cn1>>CS(=O)(=O)c1ccc(C(=O)c2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)cc1 -US20140113882A1,2,CCN=C=O.N[C@H](CNc1nc(-c2ccncc2)nc2cnccc12)Cc1ccccc1>>CCNC(=O)NC(CNc1nc(-c2ccncc2)nc2cnccc12)Cc1ccccc1 -US20080194552A1,2,CC(C#N)c1cccc(C(=O)O)c1.Nc1cncc(C#Cc2cnc(N)nc2)c1>>CC(C#N)c1cccc(C(=O)Nc2cncc(C#Cc3cnc(N)nc3)c2)c1 -US20140364433A1,2,CO.Cc1ccc(I)c(C(=O)O)c1>>COC(=O)c1cc(C)ccc1I -US20150126523A1,5,NCCCl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCCl)C(F)(F)F -US20110313196A1,2,CC(C)(C)c1ccc(CNCCc2cc(F)cc(C(F)(F)F)c2)cc1.O=C(O)c1cc(C(F)(F)F)cc(Cl)c1F>>CC(C)(C)c1ccc(CN(CCc2cc(F)cc(C(F)(F)F)c2)C(=O)c2cc(C(F)(F)F)cc(Cl)c2F)cc1 -US07521469B2,6,CC(C)(C)OC(=O)Oc1ccc(CC(NC(=O)OCc2ccccc2)C(=O)OCOC(=O)C(C)(C)C)cc1>>CC(C)(C)OC(=O)Oc1ccc(CC(N)C(=O)OCOC(=O)C(C)(C)C)cc1 -US08138175B2,6,C[C@@H]1CN(CCCN2CCCCC2)C(=O)CCN1C(=O)OCc1ccccc1>>C[C@@H]1CN(CCCN2CCCCC2)C(=O)CCN1 -US07517892B2,7,O=C(N1CCCC(COc2ccc(F)cc2)C1)C1(c2ccc(Cl)cc2)CCC1>>Fc1ccc(OCC2CCCN(CC3(c4ccc(Cl)cc4)CCC3)C2)cc1 -US08022062B2,3,N#Cc1ccc2nc(Br)sc2c1.[Zn+]CC1CCCCC1>>N#Cc1ccc2nc(CC3CCCCC3)sc2c1 -US07482340B2,1,C1CCNC1.O=C(CCl)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1>>O=C(CN1CCCC1)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1 -US20110178054A1,2,Cc1cc(OCCCC2CCN(c3nc(C4CCC4)no3)CC2)ccc1C(=O)O.NC(CO)CO>>Cc1cc(OCCCC2CCN(c3nc(C4CCC4)no3)CC2)ccc1C(=O)NC(CO)CO -US08288413B2,1,NC1CCN(C2CCOCC2)CC1.O=[N+]([O-])c1ccc(Br)cc1F>>O=[N+]([O-])c1ccc(Br)cc1NC1CCN(C2CCOCC2)CC1 -US20060116383A1,6,CCOC(=O)CC(c1ccccc1)n1cnc2cc(NC(=O)c3ccccc3N)ccc21>>Nc1ccccc1C(=O)Nc1ccc2c(c1)ncn2C(CC(=O)O)c1ccccc1 -US20090311217A1,2,CC(C)(N)CO.COc1ccc2[nH]c(C(=O)O)cc2c1>>COc1ccc2[nH]c(C(=O)NC(C)(C)CO)cc2c1 -US07671066B2,2,COc1ccc(/C(=C/c2c(Cl)cncc2Cl)OC(=O)c2ccc(N)cc2)cc1OC.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(/C(=C/c2c(Cl)cncc2Cl)OC(=O)c2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2)cc1OC -US06174877B1,2,NCc1cnccn1.O=C(Cl)CCCl>>O=C(CCCl)NCc1cnccn1 -US08859732B2,9,CCCCCCCCCCCCCCCCCCOCC(COCCCCCCCCCCCCCCCCCC)(COCCCCCCCCCCCCCCCCCC)COc1ccc(C=O)c(OC)c1.NO>>CCCCCCCCCCCCCCCCCCOCC(COCCCCCCCCCCCCCCCCCC)(COCCCCCCCCCCCCCCCCCC)COc1ccc(C=NO)c(OC)c1 -US06159964,1,CCOC(=O)CCl.COc1ccc2c(c1)CCNC2=O>>CCOC(=O)CN1CCc2cc(OC)ccc2C1=O -US20150225400A1,6,CC(C)(C)OC(=O)N1[C@H](c2cc(-c3ccc(C(F)(F)F)cc3)ccn2)CC[C@@]12CCNC2=O>>O=C1NCC[C@@]12CC[C@@H](c1cc(-c3ccc(C(F)(F)F)cc3)ccn1)N2 -US07514470B2,2,CCC(C(=O)O)N(CC(F)(F)F)c1ccc(C#N)c(Cl)c1.CCN>>CCNC(=O)C(CC)N(CC(F)(F)F)c1ccc(C#N)c(Cl)c1 -US20060287356A1,3,C#Cc1csc(N)c1C(=O)OCC.Ic1ccccc1>>CCOC(=O)c1c(C#Cc2ccccc2)csc1N -US20050119245A1,9,CC(C)N(CCNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1)C(C)C>>CC(C)N(CCNC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(Oc2ccccc2)cc1)C(C)C -US07652021B2,1,CC(C)(C)OC(=O)NC12CC3CC(C1)CC(OS(C)(=O)=O)(C3)C2.Nc1ncccn1>>CC(C)(C)OC(=O)NC12CC3CC(C1)CC(Nc1ncccn1)(C3)C2 -US09089569B2,7,Cn1ccc(COc2ccc([N+](=O)[O-])c(NCc3ccc(OC(F)(F)F)cc3F)c2)n1>>Cn1ccc(COc2ccc(N)c(NCc3ccc(OC(F)(F)F)cc3F)c2)n1 -US20060142262A1,2,CS(=O)(=O)c1ccc(-n2ncc3c(OC4CCNCC4)ncnc32)cc1.O=C(Cl)c1cccnc1>>CS(=O)(=O)c1ccc(-n2ncc3c(OC4CCN(C(=O)c5cccnc5)CC4)ncnc32)cc1 -US06187821B1,6,CCOC(=O)C(CC)(CCc1ccc(OCCCCc2ccccc2)cc1)C(=O)OCC>>CCOC(=O)C(CC)(CCc1ccc(OCCCCc2ccccc2)cc1)C(=O)O -US08956999B2,1,CC1(C)OC(C)(C)C(Cl)=CC1=O.OCc1cnc(-c2ccc(Cl)cc2)[se]1>>CC1(C)OC(C)(C)C(OCc2cnc(-c3ccc(Cl)cc3)[se]2)=CC1=O -US20070049582A1,1,ClCCCI.O=c1[nH]nnc2ccccc12>>O=c1c2ccccc2nnn1CCCCl -US20070179161A1,3,CC(C)(C)OC(=O)N(c1ccc(F)cc1)c1cc(Cl)nc2ccnn12.OB(O)c1ccccc1>>CC(C)(C)OC(=O)N(c1ccc(F)cc1)c1cc(-c2ccccc2)nc2ccnn12 -US04146630,7,Cc1c(OCc2ccccc2)cc(C(C)(C)C)cc1[N+](=O)[O-]>>Cc1c(N)cc(C(C)(C)C)cc1OCc1ccccc1 -US07829585B2,3,CCCC[Sn](CCCC)(CCCC)COC.COCc1ccc(C(=O)NCc2cc3ccc(OS(=O)(=O)C(F)(F)F)cc3o2)c(N)n1>>COCc1ccc2cc(CNC(=O)c3ccc(COC)nc3N)oc2c1 -US20130029948A1,1,CCCn1cc(Br)cn1.CCOC(=O)c1cccc(Sc2c(C)[nH]c3c(F)c(Cl)ccc23)n1>>CCCn1cc(-n2c(C)c(Sc3cccc(C(=O)OCC)n3)c3ccc(Cl)c(F)c32)cn1 -US20070123504A1,2,COCCN(C)c1ccc(N)cn1.O=C(O)c1cn(-c2ccccc2)nc1C(F)(F)F>>COCCN(C)c1ccc(NC(=O)c2cn(-c3ccccc3)nc2C(F)(F)F)cn1 -US20150141406A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#CCc1cc(Br)cs1>>CC1(C)OB(c2csc(CC#N)c2)OC1(C)C -US04039612,7,CCCCCCCCCNc1ccc(C)cc1[N+](=O)[O-]>>CCCCCCCCCNc1ccc(C)cc1N -US07351839B2,1,N#CCCl.c1ccc2c(c1)NC1CCCC21>>N#CCN1c2ccccc2C2CCCC21 -US20130324518A1,2,COC(=O)CC[C@@H](C(N)=O)N1Cc2c(OCc3ccc(CBr)cc3)cccc2C1=O>>O=C1CC[C@H](N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1 -US07105671B2,2,COC(=O)C(CC1CCC(OC)C1)c1ccc(Cl)c(Cl)c1.Nc1nccs1>>COC1CCC(CC(C(=O)Nc2nccs2)c2ccc(Cl)c(Cl)c2)C1 -US20060148858A1,1,Brc1ccc(Br)nc1.CCOC(=O)CCc1c[nH]nc1C(CC)CC>>CCOC(=O)CCc1cn(-c2ccc(Br)cn2)nc1C(CC)CC -US07994163B2,6,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(CSc3ccc(-c4csc(NCC5CC5)n4)cc3)c2CC1>>Clc1ccc2c(c1CSc1ccc(-c3csc(NCC4CC4)n3)cc1)CCNCC2 -US20050090508A1,1,C[C@H](N)C(F)(F)F.Fc1cc(F)c(-c2c(Br)nc3ncnn3c2Br)c(F)c1>>C[C@H](Nc1c(-c2c(F)cc(F)cc2F)c(Br)nc2ncnn12)C(F)(F)F -US20150111892A1,2,CC(C)(C)[Si](C)(C)OCc1c[nH]c(=O)[nH]c1=O.CCCCCCN=C=O>>CCCCCCNC(=O)n1cc(CO[Si](C)(C)C(C)(C)C)c(=O)[nH]c1=O -US20110190263A1,1,CC1(OC(=O)N2CCC(CCO)CC2)CC1.CS(=O)(=O)N1CCc2nc(CBr)ncc2C1>>CC1(OC(=O)N2CCC(CCOCc3ncc4c(n3)CCN(S(C)(=O)=O)C4)CC2)CC1 -US06194406B1,2,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.COc1ccc(-n2nnnc2C(F)(F)F)cc1C(=O)O>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(-n5nnnc5C(F)(F)F)ccc4OC)C3)CC2)nc2ccccc21 -US20060189625A1,6,COc1ccc(N2CCN(CCc3ccccc3)CC2)c(C)c1>>Cc1cc(O)ccc1N1CCN(CCc2ccccc2)CC1 -US20030191129A1,1,Cc1c(Cl)nnc(Cc2ccncc2)c1C.Nc1ccc(Cl)cc1>>Cc1c(Cc2ccncc2)nnc(Nc2ccc(Cl)cc2)c1C -US20120230951A1,2,CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1C(=O)O.NCC(=O)c1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1C(=O)NCC(=O)c1ccc(Br)cc1 -US20090274632A1,2,CC(C(=O)O)c1ccccc1.Cc1noc(C)c1Cn1cc(N)cn1>>Cc1noc(C)c1Cn1cc(NC(=O)C(C)c2ccccc2)cn1 -US04305881,4,C[C@@H](O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C.OO>>C[C@@H](O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)[C@@H]5O[C@@H]5[C@]4(C)[C@H]3CC[C@]12C -US08796455B2,3,CC1(C)OB(c2ccc3[nH]ccc3c2)OC1(C)C.Nc1nccn2c(C3CCC3)nc(I)c12>>Nc1nccn2c(C3CCC3)nc(-c3ccc4[nH]ccc4c3)c12 -US20040242928A1,7,COC(=O)C=C1CCN(C(=O)OC(C)(C)C)CC1C>>CC1CN(C(=O)OC(C)(C)C)CCC1=CCO -US20090227603A1,1,Brc1cc(Br)cc(OCc2ccccc2)c1.C[S-]>>CSc1cc(Br)cc(OCc2ccccc2)c1 -US03991202,7,Cc1cccc(Cl)c1C#N>>Cc1cccc(Cl)c1CN -US08748426B2,2,CCCCCCCCCc1ccc(C(=O)Cl)cc1.COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O>>CCCCCCCCCc1ccc(C(=O)Nc2ccc(-c3ccc4c(c3)C(=O)N([C@H](C(=O)OC)C(C)C)C4)cc2)cc1 -US07375227B2,1,CC(C)(C)OC(=O)NC1CCNCC1.Cc1cc(NC(=O)NCCCl)c2ccccc2n1>>Cc1cc(NC(=O)NCCN2CCC(NC(=O)OC(C)(C)C)CC2)c2ccccc2n1 -US06933311B2,6,CCOC(=O)C(CC(=O)OC(C)(C)C)c1cccc2cnccc12>>CC(C)(C)OC(=O)CC(C(=O)O)c1cccc2cnccc12 -US20110257151A1,1,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(Br)c1)N2.CN>>CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(NC)c1)N2 -US08569535B2,6,CCOC(=O)C1(NC(=O)c2cccc(C)c2OC(C)CC)Cc2ccccc2C1>>CCC(C)Oc1c(C)cccc1C(=O)NC1(C(=O)O)Cc2ccccc2C1 -US20140378457A1,7,N#CC1(c2ccc([N+](=O)[O-])cc2)CCOCC1>>N#CC1(c2ccc(N)cc2)CCOCC1 -US05573999,3,COC(=O)/C=C(/OC)c1ccccc1CP(=O)(OC)OC.O=Cc1ccc(OCc2ccccc2)cc1>>COC(=O)/C=C(/OC)c1ccccc1/C=C/c1ccc(OCc2ccccc2)cc1 -US07217740B2,3,C=C[Sn](CCCC)(CCCC)CCCC.O=S(=O)(c1ccc(Cl)nc1)c1ccccc1F>>C=Cc1ccc(S(=O)(=O)c2ccccc2F)cn1 -US20020183285A1,7,CCOC(=O)c1ccc2c(c1)C(C)(C)CN(C1CC1)C2>>CC1(C)CN(C2CC2)Cc2ccc(CO)cc21 -US20150174127A1,6,CC(=O)c1ccc2n1CCN(C)C21CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)c1ccc2n1CCN(C)C21CCNCC1 -US20100137313A1,4,CCOC(=O)C(Br)C(=O)c1ccccc1.COCCCNc1nc(Nc2ccc(F)c(Cl)c2)ncc1C(N)=S>>CCOC(=O)c1sc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2NCCCOC)nc1-c1ccccc1 -US05459152,2,CS(=O)(=O)Cl.NCCn1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21>>CS(=O)(=O)NCCn1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21 -US06727245B2,3,C=Cc1cccc([N+](=O)[O-])c1.Clc1cncc(Cl)c1>>O=[N+]([O-])c1cccc(/C=C/c2cncc(Cl)c2)c1 -US20150141455A1,6,CCOC(=O)C1CC1(F)c1ccccc1F>>O=C(O)C1CC1(F)c1ccccc1F -US20090247526A1,1,Cc1csc(N)n1.FC(F)(F)c1ccccc1Sc1ccnc(Cl)c1>>Cc1csc(Nc2cc(Sc3ccccc3C(F)(F)F)ccn2)n1 -US20140058098A1,9,N.O=C(O)c1ccc2c(c1)-c1nc(-c3ncnn3-c3ccccc3Cl)cn1CCO2>>NC(=O)c1ccc2c(c1)-c1nc(-c3ncnn3-c3ccccc3Cl)cn1CCO2 -US05098466,1,CC(=O)c1ncccc1C(=O)O.NNC(=O)Nc1cc(F)cc(F)c1>>CC(=O)c1ncccc1C(O)=NNC(=O)Nc1cc(F)cc(F)c1 -US05723475,2,Cc1cccc(C)c1N.O=C(Br)CBr>>Cc1cccc(C)c1NC(=O)CBr -US20150152096A1,1,COC(=O)C1=C(CBr)NC(c2nccs2)=NC1c1ccc(F)cc1Br.OC[C@H]1COCCN1>>COC(=O)C1=C(CN2CCOC[C@@H]2CO)NC(c2nccs2)=NC1c1ccc(F)cc1Br -US06407094B1,3,C#Cc1ccccc1.CC(C)(C)OC(=O)COc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1I>>CC(C)(C)OC(=O)COc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C#Cc1ccccc1 -US20150018422A1,3,CC1(C)OB(c2cc(OC3CCCCO3)ccc2F)OC1(C)C.CCOC(=O)CC(c1cccc(COc2cnc(OS(=O)(=O)C(F)(F)F)c(CC(C)(C)C)c2)c1)C1CC1>>CCOC(=O)CC(c1cccc(COc2cnc(-c3cc(OC4CCCCO4)ccc3F)c(CC(C)(C)C)c2)c1)C1CC1 -US03975384,1,CSc1nc(N)c([N+](=O)[O-])c(Cl)n1.O=S1CCNCC1>>CSc1nc(N)c([N+](=O)[O-])c(N2CCS(=O)CC2)n1 -US05910504,7,CCOC(=O)C=Cc1ccn(-c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)c1>>CCOC(=O)CCc1ccn(-c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)c1 -US20150166565A1,6,CCOC(=O)Cc1nc(N(C)C2CC2)c2c3c(sc2n1)CCCCC3>>CN(c1nc(CC(=O)O)nc2sc3c(c12)CCCCC3)C1CC1 -US20090197884A1,1,C=CCBr.O=C(CNC(=O)c1cccc(C(F)(F)F)c1)N[C@@H]1CN(C2CCOCC2)C[C@H]1O>>C=CCO[C@@H]1CN(C2CCOCC2)C[C@H]1NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 -US06517836B1,2,COC(=O)CCN.O=C(O)c1cc(Cl)c([N+](=O)[O-])cc1[N+](=O)[O-]>>COC(=O)CCNC(=O)c1cc(Cl)c([N+](=O)[O-])cc1[N+](=O)[O-] -US20050267148A1,6,CCOC(=O)CCCSc1nc2cc(OC)ccc2n1Cc1csc2ccccc12>>COc1ccc2c(c1)nc(SCCCC(=O)O)n2Cc1csc2ccccc12 -US20040209921A1,1,CC(=O)c1cc(C)ccn1.Cc1cccnc1CNCCCCNC(=O)OC(C)(C)C>>Cc1ccnc(C(C)N(CCCCNC(=O)OC(C)(C)C)Cc2ncccc2C)c1 -US20060111344A1,1,NCc1ccccc1.NS(=O)(=O)c1cccc(CCCCOCCCCCCBr)c1>>NS(=O)(=O)c1cccc(CCCCOCCCCCCNCc2ccccc2)c1 -US07541365B2,3,COC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1=O.C[Mg+]>>COC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1(C)O -US08063071B2,3,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1.OB(O)c1ccc(CNCC2CC2)s1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc(CNCC5CC5)s4)cc23)CC1 -US04837225,2,Cc1ccc(C)n1CCN.O=C(O)CN1CCCC1=O>>Cc1ccc(C)n1CCNC(=O)CN1CCCC1=O -US20090118257A1,2,Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2.NCc1ccccn1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCc1ccccn1)O2 -US20120157448A1,3,NC1=NC2(CO1)c1cc(Br)ccc1O[C@H]1CCN(C(=O)OCc3ccccc3)C[C@@H]12.OB(O)c1cccnc1F>>NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1O[C@H]1CCN(C(=O)OCc3ccccc3)C[C@@H]12 -US20090005436A1,9,CCOC(=O)Cc1cc(=O)oc2cc(O)ccc12.N>>NC(=O)Cc1cc(=O)oc2cc(O)ccc12 -US07595397B2,6,CC(C)(C)OC(=O)N1CCOC(Cc2ccccc2)C1>>c1ccc(CC2CNCCO2)cc1 -US08722883B2,6,CCOC(=O)CN1CCN(S(=O)(=O)Nc2cc(OC)nc(S(=O)(=O)Cc3cccc(F)c3F)n2)CC1>>COc1cc(NS(=O)(=O)N2CCN(CC(=O)O)CC2)nc(S(=O)(=O)Cc2cccc(F)c2F)n1 -US06642231B2,1,ClCCOc1ccccc1.O=C1CCNCC1>>O=C1CCN(CCOc2ccccc2)CC1 -US20140194383A1,6,CCOC(=O)/C=C/c1ccc(C(C)(C)O)c(O)c1>>CC(C)(O)c1ccc(/C=C/C(=O)O)cc1O -US20150266881A1,6,COC(=O)[C@@H]1C[C@H]1c1ccc(F)cc1Br>>O=C(O)[C@@H]1C[C@H]1c1ccc(F)cc1Br -US20110021523A1,2,CC(C)Oc1ccc(S(=O)(=O)Cl)cc1.Cc1ccc(C(=O)c2cc(Cl)ccc2N)cn1>>Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(OC(C)C)cc2)cn1 -US08153624B2,1,COC(=O)c1ccc(F)cc1Br.OC1CCNCC1>>COC(=O)c1ccc(N2CCC(O)CC2)cc1Br -US20080255147A1,4,NC(=S)N1CCN(C(=O)OCc2ccccc2)CC1.O=C(CBr)c1ccccc1F>>O=C(OCc1ccccc1)N1CCN(c2nc(-c3ccccc3F)cs2)CC1 -US05324622,7,CC(=O)Oc1ccc(C[SH]=S(=O)([O-])[O-])cc1>>O=S([O-])([O-])=[SH]Cc1ccc(O)cc1 -US06455708B1,2,C#CC(O)(CF)CF.O=S(=O)(Cl)c1ccccc1>>C#CC(CF)(CF)OS(=O)(=O)c1ccccc1 -US20110086889A1,2,COc1ccc(Cn2nccc2N)cc1.Cc1ccccc1-n1nnnc1SCC(=O)O>>COc1ccc(Cn2nccc2NC(=O)CSc2nnnn2-c2ccccc2C)cc1 -US09138013B2,2,NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCC[NH2+]3)c21.O=C(O)Cc1ccncc1>>NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCCN3C(=O)Cc3ccncc3)c21 -US05786356,7,Nc1c(OC[C@@H](O)CN(Cc2ccccc2)Cc2ccccc2)cccc1[N+](=O)[O-]>>Nc1cccc(OC[C@@H](O)CN(Cc2ccccc2)Cc2ccccc2)c1N -US20060167246A1,6,COC(=O)c1cc2[nH]c(-c3cccc([N+](=O)[O-])c3OCCOC3CCCCO3)c(C3CCCCC3)c2s1>>COC(=O)c1cc2[nH]c(-c3cccc([N+](=O)[O-])c3OCCO)c(C3CCCCC3)c2s1 -US20070191603A1,6,CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(Cl)ccc2OC)CCN3)cc1>>COc1ccc(Cl)cc1S(=O)(=O)N1CCNc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 -US09073929B2,3,Cc1nnc2n1-c1ccc(B3OC(C)(C)C(C)(C)O3)cc1CC2.FC(F)(F)c1cncc(Br)c1>>Cc1nnc2n1-c1ccc(-c3cncc(C(F)(F)F)c3)cc1CC2 -US20150150999A1,1,O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl.Oc1cc(O)cc(O)c1>>O=C(Cc1ccccc1Nc1c(Cl)cccc1Cl)Oc1cc(O)cc(O)c1 -US20140081017A1,3,C#CCCc1ccc(CC(=O)OC)cc1.O=[N+]([O-])c1ccc(I)cc1>>COC(=O)Cc1ccc(CCC#Cc2ccc([N+](=O)[O-])cc2)cc1 -US07718801B2,1,C[C@H](N)c1cccc(N)c1.Fc1cnc(Cl)nc1-c1cnc2c(Cl)cccn12>>C[C@H](Nc1ncc(F)c(-c2cnc3c(Cl)cccn23)n1)c1cccc(N)c1 -US05883102,6,CN(C(=O)C(F)(F)F)c1ccccc1C#N>>CNc1ccccc1C#N -US08673906B2,2,CC(Nc1ccc(F)c(Cl)c1)c1cc(C(=O)O)cc2c(=O)cc(N3CCOCC3)oc12.CNCCO>>CC(Nc1ccc(F)c(Cl)c1)c1cc(C(=O)N(C)CCO)cc2c(=O)cc(N3CCOCC3)oc12 -US05134147,7,O=C(O)CC1=Cc2ccccc21>>OCCC1=Cc2ccccc21 -US20120094992A1,1,COC(=O)CBr.COC(=O)c1ccc(O)c([N+](=O)[O-])c1>>COC(=O)COc1ccc(C(=O)OC)cc1[N+](=O)[O-] -US20110015174A1,6,CCCCCCCCc1ccc(NC(=O)NC2(CC(=O)OCC)CCN(C(=O)OCc3ccccc3)C2)cc1>>CCCCCCCCc1ccc(NC(=O)NC2(CC(=O)OCC)CCNC2)cc1 -US08217043B2,2,COC(=O)c1c(O)c2cc(Cl)cn2n(Cc2cccnc2)c1=O.C[C@H](N)C(=O)O>>C[C@H](NC(=O)c1c(O)c2cc(Cl)cn2n(Cc2cccnc2)c1=O)C(=O)O -US20090311217A1,3,CN(C)C=O.COc1ccc2c(c1)cc(C#N)n2CCN1CCN(C)CC1>>COc1ccc2c(c1)c(C=O)c(C#N)n2CCN1CCN(C)CC1 -US04347388,7,C#CC(C)(O)CCC(C)CC>>C=CC(C)(O)CCC(C)CC -US07960381B2,2,CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2CCCc2ccc(C(=O)O)s2)cc1.OCCO>>CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2CCCc2ccc(C(=O)OCCO)s2)cc1 -US07402684B2,6,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(Cc2ccc(-c3nccs3)cc2)cc1>>c1csc(-c2ccc(Cc3ccc(OC[C@H]4CCCN4)cc3)cc2)n1 -US20070043048A1,1,CC1(C)CC(Nc2nccc(-c3cc4ccc(O)cc4s3)n2)CC(C)(C)N1.CCO>>CCOc1ccc2cc(-c3ccnc(NC4CC(C)(C)NC(C)(C)C4)n3)sc2c1 -US20120316147A1,2,O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1.OC[C@@H]1CCCN1>>O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCC[C@H]1CO -US04839369,1,COc1ccc(O)cc1.ClCc1cccc(OCc2ccc3ccccc3n2)c1>>COc1ccc(OCc2cccc(OCc3ccc4ccccc4n3)c2)cc1 -US20060252768A1,6,CC(C)(C)OC(=O)N1CCC(c2ccc(N3CCCC3)cc2)CC1>>c1cc(N2CCCC2)ccc1C1CCNCC1 -US20110053943A1,7,CC(C)(O)CC1(c2ccccc2)CNC(=O)C1>>CC(C)(O)CC1(c2ccccc2)CCNC1 -US20140179567A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCCCCCCCCCCCN>>CC(C)(C)OC(=O)NCCCCCCCCCCCCN -US20040122057A1,2,COc1ccc2cc(C(OC)C(=O)O)ccc2c1.N#Cc1ccc(CN)cc1>>COc1ccc2cc(C(OC)C(=O)NCc3ccc(C#N)cc3)ccc2c1 -US08288413B2,7,CC(C)(C)OC(=O)N1CCC(Nc2cc(Cl)ccc2[N+](=O)[O-])CC1>>CC(C)(C)OC(=O)N1CCC(Nc2cc(Cl)ccc2N)CC1 -US20070293521A1,3,Brc1cnc(Nc2ccc3c(c2)OCCO3)nc1Nc1ccc2c(c1)OCCO2.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2cnc(Nc3ccc4c(c3)OCCO4)nc2Nc2ccc3c(c2)OCCO3)cc1 -US04902338,7,CC(C)N1CC(=O)N(c2cc([N+](=O)[O-])c(Cl)cc2F)C1=O>>CC(C)N1CC(=O)N(c2cc(N)c(Cl)cc2F)C1=O -US07179823B1,1,CCI.CCOC(=O)CCc1cn(Cc2cc(O)cc(OCc3csc(-c4cnccn4)n3)c2)cc1-c1ccccc1>>CCOC(=O)CCc1cn(Cc2cc(OCC)cc(OCc3csc(-c4cnccn4)n3)c2)cc1-c1ccccc1 -US04113969,9,CCOC(=O)C1(C(=O)OCC)C(C=C(Cl)Cl)C1(C)C>>CCOC(=O)C1C(C=C(Cl)Cl)C1(C)C -US04275212,1,Clc1cnc(Cl)c(Cl)c1.Oc1ccc(O)cc1>>Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1 -US20120202794A1,1,BrCC=Cc1ccccc1.CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1>>CC(C)C[C@H]1CN(CC=Cc2ccccc2)[C@@H](CC(C)C)C(=O)N1 -US20150051171A1,1,Cc1cccc(-n2nnn(C)c2=O)c1CBr.Oc1ccn(-c2cccc(Br)c2)n1>>Cc1cccc(-n2nnn(C)c2=O)c1COc1ccn(-c2cccc(Br)c2)n1 -US07553845B2,6,COc1ccc(-c2c(C)c(C(=O)c3ccc(N)c(OC)c3)n3cc(NC(=O)OC(C)(C)C)ccc23)cc1>>COc1ccc(-c2c(C)c(C(=O)c3ccc(N)c(OC)c3)n3cc(N)ccc23)cc1 -US20080004331A1,6,COC(=O)c1ccc(S(=O)(=O)CCNC(=O)OC(C)(C)C)cc1>>COC(=O)c1ccc(S(=O)(=O)CCN)cc1 -US20130225527A1,1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)nnc1Cl.CCN1CCP(=O)(c2ccc(N)c(OC)c2)CC1>>CCN1CCP(=O)(c2ccc(Nc3nnc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)c(OC)c2)CC1 -US20100234351A1,8,CC(C)(C)NC(=O)c1cccc(Oc2ccc(Nc3ncnc4c3C=C(CO)CCN4)cc2Cl)c1>>CC(C)(C)NC(=O)c1cccc(Oc2ccc(Nc3ncnc4c3C=C(C=O)CCN4)cc2Cl)c1 -US08329901B2,7,Cc1ccc([N+](=O)[O-])cc1Nc1cc(Nc2ccc(F)c(Cl)c2)ncn1>>Cc1ccc(N)cc1Nc1cc(Nc2ccc(F)c(Cl)c2)ncn1 -US06452019B1,7,Nc1c(N=O)cnn1CCO>>Nc1cnn(CCO)c1N -US20070299068A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOc1ccc2cc[nH]c2c1>>CCOc1ccc2ccn(C(=O)OC(C)(C)C)c2c1 -US20100076026A1,1,Nc1c2c(nn1-c1ccccc1)CCCC2.O=C1CCCCC1>>c1ccc(-n2nc3c(c2NC2CCCCC2)CCCC3)cc1 -US08501166B2,1,CCOCn1c(-c2nc(Cl)ncc2Cl)cc2c(C(=O)NC3CC3)cccc21.N[C@@H]1CCC[C@@H]1O>>CCOCn1c(-c2nc(N[C@@H]3CCC[C@@H]3O)ncc2Cl)cc2c(C(=O)NC3CC3)cccc21 -US04839365,8,COC(=O)c1csc2c(CSc3nc4ccccc4[nH]3)nccc12.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1csc2c(CS(=O)c3nc4ccccc4[nH]3)nccc12 -US20150284382A1,1,COC[C@H](F)CNC(=O)c1cnc(Cl)cc1NC(C)C.N#Cc1cnc(N)c(F)c1>>COC[C@H](F)CNC(=O)c1cnc(Nc2ncc(C#N)cc2F)cc1NC(C)C -US20100152160A1,2,CC(C)(C)OC(=O)N1CC(C(=O)O)Oc2cc(OCc3ccccc3)c(Cl)cc21.N#CC1(Cc2ccc(F)nc2)CCNCC1>>CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)nc3)CC2)Oc2cc(OCc3ccccc3)c(Cl)cc21 -US20120035370A1,2,CC(C)(C)OC(=O)NCc1ccnc2[nH]ccc12.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NCc1ccnc2c1ccn2S(C)(=O)=O -US20090023731A1,2,Nc1cccc(OCCCN2CCOCC2)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Nc1cccc(OCCCN2CCOCC2)c1)Oc1ccc([N+](=O)[O-])cc1 -US20070066639A1,3,CCOCc1nc2c(N)nc3cc(Br)cnc3c2n1CCCON=C(C)C.OB(O)c1ccccc1>>CCOCc1nc2c(N)nc3cc(-c4ccccc4)cnc3c2n1CCCON=C(C)C -US20020115853A1,3,Cn1c(=O)[nH]c2ccc(Br)cc21.O=[N+]([O-])c1cccc(B(O)O)c1>>Cn1c(=O)[nH]c2ccc(-c3cccc([N+](=O)[O-])c3)cc21 -US08324254B2,1,CC(C)Oc1ncc(-c2nc(-c3ccc4[nH]ncc4c3)no2)cc1Cl.CCOC(=O)C(C)(C)CBr>>CCOC(=O)C(C)(C)Cn1ncc2cc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)ccc21 -US08324396B2,3,CC(C)(C)OC(=O)Nc1nc(Br)ns1.CS(=O)(=O)c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)Nc1nc(-c2ccc(S(C)(=O)=O)cc2)ns1 -US05015658,1,CC1(C)CCSc2ccc(C(=O)O)cc21.O=C(OCc1ccccc1)c1ccc(O)cc1>>CC1(C)CCSc2ccc(C(=O)Oc3ccc(C(=O)OCc4ccccc4)cc3)cc21 -US05670546,2,CC(=O)Oc1ccccc1C(=O)O.COc1cc(CC(=O)NCCCc2ccc(C)c(C)c2)ccc1OCCN>>COc1cc(CC(=O)NCCCc2ccc(C)c(C)c2)ccc1OCCNC(=O)c1ccccc1OC(C)=O -US20130345192A1,2,NC(=O)c1cnc2[nH]ccc2c1NC1CCCNC1.O=C=NCc1ccccc1>>NC(=O)c1cnc2[nH]ccc2c1NC1CCCN(C(=O)NCc2ccccc2)C1 -US07361672B2,2,O=C(O)Cc1csc(NC(=O)c2ccc(Cl)cc2)n1.c1ccc(CN2CCNCC2)cc1>>O=C(Nc1nc(CC(=O)N2CCN(Cc3ccccc3)CC2)cs1)c1ccc(Cl)cc1 -US07723329B2,9,[N-]=[N+]=NCCCOc1ccc2[nH]nc(S(=O)(=O)c3cccc4ccccc34)c2c1>>NCCCOc1ccc2[nH]nc(S(=O)(=O)c3cccc4ccccc34)c2c1 -US07214673B2,1,C=O.Cc1ccc2c(c1)C(N1CCN[C@@H](CCc3ccccc3)C1)=Nc1ccccc1N2>>Cc1ccc2c(c1)C(N1CCN(C)[C@@H](CCc3ccccc3)C1)=Nc1ccccc1N2 -US05026856,1,Nc1cccc2c1CNC2.O=C(O)c1cn(-c2ccc(F)cc2)c2c(F)c(F)c(F)cc2c1=O>>Nc1cccc2c1CN(c1c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4)c3c1F)C2 -US20020193389A1,1,C1COCCN1.N#Cc1cccc(O)c1>>N#Cc1cccc(N2CCOCC2)c1 -US07919502B2,3,CC1(C)OB(c2ccc(C(=O)N3CCC(N4CCCC4)CC3)cc2)OC1(C)C.Fc1ccc(F)c(CN2CCNc3ncc(I)cc32)c1Cl>>O=C(c1ccc(-c2cnc3c(c2)N(Cc2c(F)ccc(F)c2Cl)CCN3)cc1)N1CCC(N2CCCC2)CC1 -US20110230461A1,6,CC(C)(C)OC(=O)N1CCC2(CC1)CN([C@@H]1CCc3cc(-c4cnc(C(N)=O)cn4)ccc31)C2>>NC(=O)c1cnc(-c2ccc3c(c2)CC[C@H]3N2CC3(CCNCC3)C2)cn1 -US08853226B2,1,CCOC(=O)c1cnc2c(OC)cccc2c1Cl.NC1CCCCC1>>CCOC(=O)c1cnc2c(OC)cccc2c1NC1CCCCC1 -US20090176829A1,3,C#Cc1ccc(F)cc1.Ic1ccc(OCc2ccc3ccccc3n2)cc1>>Fc1ccc(C#Cc2ccc(OCc3ccc4ccccc4n3)cc2)cc1 -US08530477B2,1,CC(C)(C)OC(=O)N1C2CCC1CN(c1ccc(Br)cc1)C2.CS(=O)(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1C2CCC1CN(c1ccc(N3CCN(S(C)(=O)=O)CC3)cc1)C2 -US20050277670A1,2,C[C@H](CCN)N1CCC(Nc2ccc(O[Si](C)(C)C(C)(C)C)cc2)CC1.Cc1ncnc(C)c1C(=O)O>>Cc1ncnc(C)c1C(=O)NCC[C@@H](C)N1CCC(Nc2ccc(O[Si](C)(C)C(C)(C)C)cc2)CC1 -US20140171430A1,1,Cc1cc(Cl)nc(C(F)(F)F)n1.O=C(c1cc(F)ccc1-n1nccn1)N1CC2CNCC2C1>>Cc1cc(N2CC3CN(C(=O)c4cc(F)ccc4-n4nccn4)CC3C2)nc(C(F)(F)F)n1 -US20100075978A1,2,CN(C)CCCN1CCNCC1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1>>CN(C)CCCN1CCN(C(=O)c2ccc(S(=O)(=O)Nc3ccccc3Oc3ccc(Cl)cc3Cl)cc2)CC1 -US20140171430A1,2,CCCOc1ccc(C)nc1C(=O)O.Cc1cc(C)nc(N2CC3CNCC3C2)n1>>CCCOc1ccc(C)nc1C(=O)N1CC2CN(c3nc(C)cc(C)n3)CC2C1 -US20050038072A1,1,CSc1ccc(CO)cc1.O=C1CCNCC1C(c1ccccc1)c1ccccc1>>CSc1ccc(CN2CCC(=O)C(C(c3ccccc3)c3ccccc3)C2)cc1 -US20040176361A1,1,Cc1cccc2cc(Cl)[nH]c(=O)c12.OCCN1CCNCC1>>Cc1cccc2cc(N3CCN(CCO)CC3)[nH]c(=O)c12 -US07524838B2,3,CCCC[Sn](CCCC)(CCCC)c1cn(S(=O)(=O)c2ccc(C)cc2)nc1OCc1ccccc1.Clc1ccc(Br)s1>>Cc1ccc(S(=O)(=O)n2cc(-c3ccc(Cl)s3)c(OCc3ccccc3)n2)cc1 -US20120046267A1,1,BrCc1ccccn1.CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5cccc(O)c5)cc34)cn2)CC1>>CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5cccc(OCc6ccccn6)c5)cc34)cn2)CC1 -US05192783,2,CCCCC(CO)c1ccc(Cl)cc1Cl.CS(=O)(=O)Cl>>CCCCC(COS(C)(=O)=O)c1ccc(Cl)cc1Cl -US20100298140A1,7,CC(=O)c1cnc(-c2ccc(Cl)cc2)s1>>CC(O)c1cnc(-c2ccc(Cl)cc2)s1 -US08476286B2,3,COc1cc2nc(Cl)nc(-c3ccc(C(C)C)cc3)c2cc1OC.C[Mg+]>>COc1cc2nc(C)nc(-c3ccc(C(C)C)cc3)c2cc1OC -US20110213143A1,7,C/C=C\c1ccc2c(c1)CCc1c(CC3CCCN(C(=O)OC(C)(C)C)C3=O)ncn1-2>>CCCc1ccc2c(c1)CCc1c(CC3CCCN(C(=O)OC(C)(C)C)C3=O)ncn1-2 -US20100048568A1,2,CNC.Cc1ccc(S(=O)(=O)n2cc(S(=O)(=O)Cl)c3cc(F)ccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(S(=O)(=O)N(C)C)c3cc(F)ccc32)cc1 -US07582651B2,2,Cc1cc(C)c2c(C#N)c(/C=C/C(=O)O)n([C@H]3CCCc4ccccc43)c2n1.Nc1ccc(Cl)cc1>>Cc1cc(C)c2c(C#N)c(/C=C/C(=O)Nc3ccc(Cl)cc3)n([C@H]3CCCc4ccccc43)c2n1 -US04360525,7,CN1CCC(N(C(=O)c2cc(Cl)ccc2F)c2ccccc2[N+](=O)[O-])CC1>>CN1CCC(N(C(=O)c2cc(Cl)ccc2F)c2ccccc2N)CC1 -US06391873B1,9,CN1Cc2c(C(N)=O)ncn2-c2cccc(Cl)c2C1=O>>CN1Cc2c(C#N)ncn2-c2cccc(Cl)c2C1=O -US05705494,2,CCCCNC.O=S(=O)(Cl)CCCCCCl>>CCCCN(C)S(=O)(=O)CCCCCCl -US20090221555A1,1,CCN1C(=O)OCCc2ccc(N)cc21.CNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl>>CCN1C(=O)OCCc2ccc(Nc3ncc(Cl)c(Nc4ccccc4C(=O)NC)n3)cc21 -US20120214767A1,9,COc1cc2c(cc1C)C(=O)CCC2.NO>>COc1cc2c(cc1C)/C(=N/O)CCC2 -US20060084690A1,2,CO.Cc1ccc(-c2oncc2CCC(=O)O)cc1>>COC(=O)CCc1cnoc1-c1ccc(C)cc1 -US08426611B2,1,CBr.CN1C2CC[C@@H]1[C@@H](OC(=O)[C@](O)(c1ccccc1)C1CCCC1)C2>>C[N+]1(C)C2CC[C@@H]1[C@@H](OC(=O)[C@](O)(c1ccccc1)C1CCCC1)C2 -US07638517B2,9,ClCCC(c1ccccc1)n1ccc2c(Cl)ncnc21>>ClCCC(c1ccccc1)n1ccc2cncnc21 -US04331678,2,CCNCC.CSc1cc(C(C)(C)C)nn1C(=O)Cl>>CCN(CC)C(=O)n1nc(C(C)(C)C)cc1SC -US20110301155A1,7,O=[N+]([O-])c1ccn(CCO)n1>>Nc1ccn(CCO)n1 -US05112861,3,CCOC(=O)CC#N.O=Cc1cc(O)c(O)c([N+](=O)[O-])c1>>CCOC(=O)C(C#N)=Cc1cc(O)c(O)c([N+](=O)[O-])c1 -US08916560B2,1,COC(=O)c1ccc2nc(-c3ccccc3)c(Br)nc2c1.O[C@@H]1CCNC1>>COC(=O)c1ccc2nc(-c3ccccc3)c(N3CC[C@@H](O)C3)nc2c1 -US05420270,1,O=Cc1ccccc1O.O=[N+]([O-])c1cc(Cl)ccc1Cl>>O=Cc1ccccc1Oc1ccc(Cl)cc1[N+](=O)[O-] -US06500846B1,2,Nc1ccc2oc(-c3ccc4c(c3)OCO4)c(O)c(=O)c2c1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=c1c(O)c(-c2ccc3c(c2)OCO3)oc2ccc(NS(=O)(=O)c3ccc(Br)cc3)cc12 -US20110046134A1,2,Cc1ccsc1C(=O)O.O=C(NCC(=O)N1CCNCC1)c1ccc(OCc2ccccc2)cc1>>Cc1ccsc1C(=O)N1CCN(C(=O)CNC(=O)c2ccc(OCc3ccccc3)cc2)CC1 -US20140114068A1,7,COc1cccc(C(=O)NC23C(=O)c4c([N+](=O)[O-])cccc4C2(O)Oc2cc(C(C)C)ccc23)c1>>COc1cccc(C(=O)NC23C(=O)c4c(N)cccc4C2(O)Oc2cc(C(C)C)ccc23)c1 -US20070191595A1,1,CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5.O=C1c2ccccc2C(=O)N1CCCBr>>CN1CC[C@]23c4c5ccc(OCCCN6C(=O)c7ccccc7C6=O)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5 -US20130102629A1,2,C[C@H]1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1.Nc1cc(Br)cnc1N>>C[C@H]1C[C@@H](C(=O)Nc2cc(Br)cnc2N)N(C(=O)OC(C)(C)C)C1 -US20140378487A1,1,CNCc1ccc(Oc2cncc(C#N)c2)c(C#N)c1.COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O>>COc1ccc2c(c1)CCn1c-2cc(N(C)Cc2ccc(Oc3cncc(C#N)c3)c(C#N)c2)nc1=O -US08664230B2,3,CC1(C)OB(c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3F)c2)OC1(C)C.Clc1ccc2ncnc(NC3CCOCC3)c2n1>>O=S(=O)(Nc1cc(-c2ccc3ncnc(NC4CCOCC4)c3n2)cnc1Cl)c1ccc(F)cc1F -US04311698,2,CC(=O)N[C@H](CC(N)=O)C(=O)O.Nc1ccc(-c2ccc(C(=O)O)c(=O)[nH]2)cc1>>CC(=O)N[C@H](CC(N)=O)C(=O)Nc1ccc(-c2ccc(C(=O)O)c(=O)[nH]2)cc1 -US04996347,1,CN(C)C(=S)Cl.N#Cc1cccc(C(=O)c2ccc(O)cc2)c1>>CN(C)C(=S)Oc1ccc(C(=O)c2cccc(C#N)c2)cc1 -US20070219210A1,2,CC(C)(N)CO.COc1ccc(-n2nc(C(=O)O)cc2-c2ccccn2)cn1>>COc1ccc(-n2nc(C(=O)NC(C)(C)CO)cc2-c2ccccn2)cn1 -US20110034469A1,6,O=C(N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)c1ccccc1)OCc1ccccc1>>N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)c1ccccc1 -US20070244125A1,1,N#Cc1cccc(B(O)O)c1.O=C(c1ccc2[nH]c(C(=O)N3CCS(=O)(=O)CC3)cc2c1)N1CCN(C2CCC2)CC1>>N#Cc1cccc(-n2c(C(=O)N3CCS(=O)(=O)CC3)cc3cc(C(=O)N4CCN(C5CCC5)CC4)ccc32)c1 -US08492437B2,2,CN(Cc1cc(CC(=O)OC(C)(C)C)ccc1Oc1ccc(C(=O)O)cc1)S(C)(=O)=O.NCCc1ccc(Cl)cc1>>CN(Cc1cc(CC(=O)OC(C)(C)C)ccc1Oc1ccc(C(=O)NCCc2ccc(Cl)cc2)cc1)S(C)(=O)=O -US20120028931A1,1,COc1ccc(CCl)cc1.OCc1cc(-c2cccs2)[nH]n1>>COc1ccc(Cn2nc(CO)cc2-c2cccs2)cc1 -US04067993,6,CCOC(=O)CNC(=O)c1cccc2c(-c3ccccc3)c([N+](=O)[O-])oc12>>O=C(O)CNC(=O)c1cccc2c(-c3ccccc3)c([N+](=O)[O-])oc12 -US20150175623A1,1,CCOC(=O)[C@@H](Cc1ccccc1O)Oc1ncnc2sc(I)c(-c3ccc(OCCN4CCN(C)CC4)c(Cl)c3C)c12.OCc1ccnn1CC(F)(F)F>>CCOC(=O)[C@@H](Cc1ccccc1OCc1ccnn1CC(F)(F)F)Oc1ncnc2sc(I)c(-c3ccc(OCCN4CCN(C)CC4)c(Cl)c3C)c12 -US08362023B2,8,CSc1nccc(C(O)c2cnc(Cl)nc2Cl)n1>>CSc1nccc(C(=O)c2cnc(Cl)nc2Cl)n1 -US06107329,2,COC(=O)CN.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>COC(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1 -US20140364433A1,1,C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-c2ncccn2)[C@@H]1CN.FC(F)(F)c1cnc(Cl)nc1>>C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-c2ncccn2)[C@@H]1CNc1ncc(C(F)(F)F)cn1 -US08026247B2,6,CC(C)(C)OC(=O)Nc1cc(Sc2ccc3c(C(=O)Nc4ccc(F)c(C(F)(F)F)c4)cccc3c2)ncn1>>Nc1cc(Sc2ccc3c(C(=O)Nc4ccc(F)c(C(F)(F)F)c4)cccc3c2)ncn1 -US20050267093A1,7,COc1cc([N+](=O)[O-])ccc1OCCN1CCC(C(N)=O)CC1>>COc1cc(N)ccc1OCCN1CCC(C(N)=O)CC1 -US08163743B2,3,COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1NS(=O)(=O)c1ccc(F)cc1F.Cc1ccc(S(=O)(=O)n2ncc3c(NC(=O)c4csc(CN5C[C@H](C)O[C@H](C)C5)n4)cc(Br)cc32)cc1>>COc1ncc(-c2cc(NC(=O)c3csc(CN4C[C@H](C)O[C@H](C)C4)n3)c3cnn(S(=O)(=O)c4ccc(C)cc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F -US20070149577A1,2,COc1ccc(F)cc1-c1ccc(C(C)N)cc1.Cn1cc(S(=O)(=O)Cl)c(C(F)(F)F)n1>>COc1ccc(F)cc1-c1ccc([C@@H](C)NS(=O)(=O)c2cn(C)nc2C(F)(F)F)cc1 -US20120232056A1,6,COC(=O)c1ccc2nc(-c3cc[nH]c3)c(N3CCC[C@@H]3C)nc2c1>>C[C@H]1CCCN1c1nc2cc(C(=O)O)ccc2nc1-c1cc[nH]c1 -US08816090B2,7,COC(=O)C1(C=O)CCCC1>>COC(=O)C1(CO)CCCC1 -US20100016401A1,2,Cc1nc(C(=O)O)c(-c2cccc(Cl)c2)s1.O=C(NC[C@H]1NC[C@H]2C[C@H]21)C(F)(F)F>>Cc1nc(C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)C(F)(F)F)c(-c2cccc(Cl)c2)s1 -US06677324B1,7,CCCCCCCCCN(C)CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2[C@@H](F)C[C@]3(C)C(=O)CC[C@H]3[C@@H]21>>CCCCCCCCCN(C)CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2[C@@H](F)C[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]21 -US20120178934A1,2,CC(C)S(=O)(=O)Cl.COCCOCOc1ccc(C(=O)NC[C@@H](C(=O)OC)N2CCNCC2)cc1>>COCCOCOc1ccc(C(=O)NC[C@@H](C(=O)OC)N2CCN(S(=O)(=O)C(C)C)CC2)cc1 -US20140249314A1,2,NCC(F)(F)F.O=C(O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12>>O=C(NCC(F)(F)F)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12 -US05075301,1,C=O.N#CC(C#N)=C1NCCN1CCNCc1ccc(CN2CCCCC2)o1>>CN(CCN1CCNC1=C(C#N)C#N)Cc1ccc(CN2CCCCC2)o1 -US20140094462A1,3,C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C=O.C[Mg+]>>C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1[C@H](C)O -US04260611,1,CNC.OCc1c(Cl)nc(-c2ccccc2)c2ccccc12>>CN(C)Cc1c(Cl)nc(-c2ccccc2)c2ccccc12 -US20150197486A9,1,CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)CCl.COC(=O)/C=C/C(=O)O>>COC(=O)/C=C/C(=O)OCC(=O)N1CCC[C@H]1C(=O)OC(C)(C)C -US05556864,3,O=CCCc1ccc2ccccc2c1.c1ccc(COc2ccccc2C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>C(=Cc1ccccc1OCc1ccccc1)CCc1ccc2ccccc2c1 -US07592347B2,1,CC(C)I.C[C@H]1CN(C(=O)OCc2ccccc2)CCN1>>CC(C)N1CCN(C(=O)OCc2ccccc2)CC1C -US05231188,7,N#CC(O)C1Cc2ccccc2N1C(=O)OCc1ccccc1>>NCC(O)C1Cc2ccccc2N1C(=O)OCc1ccccc1 -US07312241B2,3,CCOP(=O)(CC#N)OCC.CCOc1cc(C(=O)c2cc(OC)cc(OC)c2)ccc1OC>>CCOc1cc(C(=CC#N)c2cc(OC)cc(OC)c2)ccc1OC -US05574064,2,CC[C@H](C)[C@H](NC(=O)OC(C)C)C(=O)O.C[C@@H](N)C(=O)Nc1ccc(C#N)cc1>>CC[C@H](C)[C@H](NC(=O)OC(C)C)C(=O)N[C@H](C)C(=O)Nc1ccc(C#N)cc1 -US04088772,7,O=C(C1CCCC1)N1C=C2c3ccccc3C3CC2(C1)c1ccccc13>>C1=C2c3ccccc3C3CC2(CN1CC1CCCC1)c1ccccc13 -US05719157,8,CCOC(=O)c1c(SCc2nccn2C)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1c(S(=O)Cc2nccn2C)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1 -US20150031685A1,2,CCOC(=O)c1cccc([C@@H](CN2CC[C@H](O[Si](C)(C)C(C)(C)C)C2)N(C)C(=O)OCc2ccccc2)c1.NN>>CN(C(=O)OCc1ccccc1)[C@H](CN1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1cccc(C(=O)NN)c1 -US20030139409A1,2,CN(C)CCN.Cc1cccc2c1ccc1nc3cccc(C(=O)O)c3nc12>>Cc1cccc2c1ccc1nc3cccc(C(=O)NCCN(C)C)c3nc12 -US20060004084A1,1,C1COCCN1.CC1(C)OC(=C2C(=O)Nc3ccc(F)cc32)c2ccc(CCCOS(C)(=O)=O)cc21>>CC1(C)OC(=C2C(=O)Nc3ccc(F)cc32)c2ccc(CCCN3CCOCC3)cc21 -US07384931B2,2,O=C(O)C[C@@H]1Cc2cc(Cl)c3[nH]ncc3c2CN(Cc2ccncc2)C1=O.O=c1[nH]c2ccccc2cc1C1CCNCC1>>O=C(C[C@@H]1Cc2cc(Cl)c3[nH]ncc3c2CN(Cc2ccncc2)C1=O)N1CCC(c2cc3ccccc3[nH]c2=O)CC1 -US06492416B1,3,CC1(C)OC(c2ccc(S(C)(=O)=O)cc2)=C(I)C1=O.OB(O)c1ccco1>>CC1(C)OC(c2ccc(S(C)(=O)=O)cc2)=C(c2ccco2)C1=O -US20120157448A1,3,CC1(C)OB(c2ccc3c(c2)[C@@]2(COC(N)=N2)[C@H]2CC(=O)CC[C@@H]2O3)OC1(C)C.N#Cc1cc(Cl)cc(Br)c1>>N#Cc1cc(Cl)cc(-c2ccc3c(c2)[C@@]2(COC(N)=N2)[C@H]2CC(=O)CC[C@@H]2O3)c1 -US20150218149A1,3,CC(C)(C)[Si]1(C(C)(C)C)OC[C@H]2OC[C@@H](Oc3nc4c(F)c(I)c(F)cc4n3COCC[Si](C)(C)C)[C@@H]2O1.CC1(C)OB(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)OC1(C)C>>CC1(C)OB(c2ccc(-c3c(F)cc4c(nc(O[C@@H]5CO[C@@H]6CO[Si](C(C)(C)C)(C(C)(C)C)O[C@H]65)n4COCC[Si](C)(C)C)c3F)cc2)OC1(C)C -US20060199800A1,1,CC#CCOc1cc(Cl)ncn1.CC1CCCNC1>>CC#CCOc1cc(N2CCCC(C)C2)ncn1 -US08309581B2,7,N#Cc1ccc(C#Cc2cc(Cl)ccc2-c2nc3ccccc3n2CC2CCCCC2)cc1>>N#Cc1ccc(CCc2cc(Cl)ccc2-c2nc3ccccc3n2CC2CCCCC2)cc1 -US20030119807A1,6,CCCS(=O)(=O)Cc1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CCCS(=O)(=O)Cc1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1 -US20140235855A1,1,COc1ccc2ncc(Cl)c(C(O)C(O)CC3CCC(NC(=O)OC(C)(C)C)CO3)c2c1F>>COc1ccc2ncc3c(c2c1F)C(O)C(C[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CO1)O3 -US08048909B2,2,CCOC(=O)c1c[nH]c(-c2ccccc2)c1F.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)c1cn(S(=O)(=O)c2ccccc2)c(-c2ccccc2)c1F -US20150119380A1,1,C[S-].Nc1cc(Cl)ncn1>>CSc1cc(N)ncn1 -US20100144741A1,1,CC(=O)N[C@@H](Cc1ccc(N)cc1)[C@H]1CN(C2(c3cccc(C(C)C)c3)CC2)C(=O)O1.Clc1cc(-c2ccccc2)ccn1>>CC(=O)N[C@@H](Cc1ccc(Nc2cc(-c3ccccc3)ccn2)cc1)[C@H]1CN(C2(c3cccc(C(C)C)c3)CC2)C(=O)O1 -US08563565B2,9,COc1ncc(C)c(-c2ccc(-c3c(C(=O)O)cnn3[C@H]3CCOC3)c(F)c2)c1C.N>>COc1ncc(C)c(-c2ccc(-c3c(C(N)=O)cnn3[C@H]3CCOC3)c(F)c2)c1C -US03937830,2,CC(C)(C)C(=O)Cl.CC(c1ccccc1)C1(O)C(=O)NC(=O)NC1=O>>CC(c1ccccc1)C1(OC(=O)C(C)(C)C)C(=O)NC(=O)NC1=O -US20100331312A1,7,COC(=O)Cc1ccc(OCc2ccc(OC)cc2)c(Cl)c1>>COc1ccc(COc2ccc(CCO)cc2Cl)cc1 -US05721234,2,CC(=O)OC(C)=O.NC1CCc2c([N+](=O)[O-])cc3[nH]c(=O)c(=O)[nH]c3c2C1>>CC(=O)NC1CCc2c([N+](=O)[O-])cc3[nH]c(=O)c(=O)[nH]c3c2C1 -US05693652,1,Clc1ccc2nc(Cl)nc(NCc3ccc4c(c3)OCO4)c2c1.OC1COC(c2ccccc2)OC1>>Clc1ccc2nc(OC3COC(c4ccccc4)OC3)nc(NCc3ccc4c(c3)OCO4)c2c1 -US20100249192A1,4,N#Cc1cc(-c2ccc(Oc3cc(F)ccc3Br)cc2)no1.[N-]=[N+]=[N-]>>Fc1ccc(Br)c(Oc2ccc(-c3cc(-c4nnn[nH]4)on3)cc2)c1 -US05109004,9,N#C[Cu].N#Cc1cc(C(F)(F)F)cc(Br)c1N>>N#Cc1cc(C(F)(F)F)cc(C#N)c1N -US20070173488A1,6,CC(C)(C)OC(=O)Nc1n[nH]c2nc(NC(=O)C3CC3)sc12>>Nc1n[nH]c2nc(NC(=O)C3CC3)sc12 -US06420362B1,1,CON=C(C(C)=NN)c1ccccc1.CON=C(C1=NOCCO1)c1ccccc1C=O>>CON=C(C(C)=NN=Cc1ccccc1C(=NOC)C1=NOCCO1)c1ccccc1 -US20090264405A1,3,Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(Br)ccc3o2)cc1.OB(O)c1cccnc1>>Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(-c4cccnc4)ccc3o2)cc1 -US20090062279A1,3,Brc1nccc2ccccc12.COc1ccccc1B(O)O>>COc1ccccc1-c1nccc2ccccc12 -US20150175604A1,3,CC(C)(C)[Si](OCc1cc(Cl)cc(Cn2c(Br)cc3nc(Cl)ccc32)c1)(c1ccccc1)c1ccccc1.CC1(C)OB(c2ccnn2C2CCCCO2)OC1(C)C>>CC(C)(C)[Si](OCc1cc(Cl)cc(Cn2c(-c3ccnn3C3CCCCO3)cc3nc(Cl)ccc32)c1)(c1ccccc1)c1ccccc1 -US20100004239A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CC2.O=C1Cc2c(cccc2-c2cccc(F)c2)N1>>Cc1c(C=C2C(=O)Nc3cccc(-c4cccc(F)c4)c32)[nH]c2c1C(=O)N(CCN1CCCCC1)CC2 -US20150133428A1,6,CC(C)(C)OC(=O)N1Cc2c(C(N)=O)c(-c3ccc(F)c(Cl)c3)nn2CC12CC2>>NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CNC1(CC1)C2 -US04863920,3,C#CCO.CN1Cc2c(I)ncn2-c2ccccc2C1=O>>CN1Cc2c(C#CCO)ncn2-c2ccccc2C1=O -US20030109527A1,7,CN(C)S(=O)(=O)c1c(Cl)ccc([N+](=O)[O-])c1O>>CN(C)S(=O)(=O)c1c(Cl)ccc(N)c1O -US20090192138A1,1,BrCc1ccccc1.COC(=O)c1c(Cl)[nH]c2c(=O)n(CC(=O)c3cccc(OC)c3)cnc12>>COC(=O)c1c(Cl)n(Cc2ccccc2)c2c(=O)n(CC(=O)c3cccc(OC)c3)cnc12 -US08765730B2,3,CON(C)C(=O)CC(c1ccccc1)c1ccccc1.Cc1cc(Br)ccn1>>Cc1cc(C(=O)CC(c2ccccc2)c2ccccc2)ccn1 -US20080262064A1,2,COCC(C)(C)OC(=O)c1c(N)nc(OC)n1-c1ccc2c(c1)OCO2.O=C(Cl)C1COc2ccccc2O1>>COCC(C)(C)OC(=O)c1c(NC(=O)C2COc3ccccc3O2)nc(OC)n1-c1ccc2c(c1)OCO2 -US20130095123A1,1,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](Cc1ccccc1)c1nnc(-c2ccccc2)o1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C.O=CCCC(=O)O>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](Cc1ccccc1)c1nnc(-c2ccccc2)o1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)O)C(C)C -US20080306036A1,3,CC(C)(C)C(=O)Oc1ccc(C(=O)c2ccc(OC(=O)C(C)(C)C)cc2)cc1.CCCCC(=O)c1cccc(O)c1>>CCCCC(=C(c1ccc(OC(=O)C(C)(C)C)cc1)c1ccc(OC(=O)C(C)(C)C)cc1)c1cccc(O)c1 -US20050080124A1,2,COc1ccc(N)cc1-c1c(Cl)cnn1C.O=C=NCc1ccccc1>>COc1ccc(NC(=O)NCc2ccccc2)cc1-c1c(Cl)cnn1C -US20120046293A1,1,NC1CC1.O=Cc1cc(Br)cc(Cl)c1Cl>>Clc1cc(Br)cc(CNC2CC2)c1Cl -US20140121246A1,10,Cc1cc(F)cc2c1OC(C)(C)C2=O.O=C1CCC(=O)N1Br>>CC1(C)Oc2c(CBr)cc(F)cc2C1=O -US06737425B1,1,CC(C)Nc1ccccc1.CCOC(=O)CBr>>CCOC(=O)CN(c1ccccc1)C(C)C -US20080312192A1,1,CC(C)N1CCN(Cc2cc(NC(=O)Nc3ccc(Oc4cc(Cl)ncn4)cc3)cc(C(F)(F)F)c2)CC1.CN>>CNc1cc(Oc2ccc(NC(=O)Nc3cc(CN4CCN(C(C)C)CC4)cc(C(F)(F)F)c3)cc2)ncn1 -US08614195B2,6,CCc1ccc([C@@H]2O[C@H](COC(=O)[C@H](NC(=O)OC(C)(C)C)C(C)C)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc2c(c1)OCCO2>>CCc1ccc([C@@H]2O[C@H](COC(=O)[C@H](N)C(C)C)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc2c(c1)OCCO2 -US20060020003A1,1,COc1ccc(-c2ccc(C=O)cc2)cc1Br.NCc1ccccc1>>COc1ccc(-c2ccc(/C=N\Cc3ccccc3)cc2)cc1Br -US05086051,2,CN1CCC(O)CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC2CCN(C)CC2)cc1 -US08841455B2,6,CCc1nn(Cc2cccc(OCCNC(=O)OC(C)(C)C)n2)c2cccc(NC(=O)c3cnc4ccccn34)c12>>CCc1nn(Cc2cccc(OCCN)n2)c2cccc(NC(=O)c3cnc4ccccn34)c12 -US20130303518A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CC(O)CN1CCOCC1)CCC2.Cc1cccc2c1CC(=O)N2>>Cc1cccc2c1/C(=C/c1[nH]c3c(c1C)C(=O)N(C[C@H](O)CN1CCOCC1)CCC3)C(=O)N2 -US04977154,1,C1CNCCN1.Nc1c(F)c(F)c(Cl)c2c1c(=O)c(C(=O)O)cn2C1CC1>>Nc1c(F)c(N2CCNCC2)c(Cl)c2c1c(=O)c(C(=O)O)cn2C1CC1 -US07649093B2,6,CCOC(=O)CC(Cc1cccc(OC)c1)C(C)C>>COc1cccc(CC(CC(=O)O)C(C)C)c1 -US07622471B2,4,CCOC(=O)C(=O)CC(=O)c1ccccn1.Cc1ccc(NN)cn1>>CCOC(=O)c1cc(-c2ccccn2)n(-c2ccc(C)nc2)n1 -US20040147612A1,1,CC(CNS(=O)(=O)C(C)C)c1ccc2cc(O)ccc2c1.N#CCBr>>CC(CNS(=O)(=O)C(C)C)c1ccc2cc(OCC#N)ccc2c1 -US20150126503A1,1,COc1cc(C#N)ccc1O.COc1ccc(CBr)cc1>>COc1ccc(COc2ccc(C#N)cc2OC)cc1 -US04166735,1,CC(C)Br.Cc1ccccc1O>>Cc1ccccc1OC(C)C -US20090054508A1,2,Cn1cccc1C(=O)O.Nc1ccccc1/C=C/c1n[nH]c2ccccc12>>Cn1cccc1C(=O)Nc1ccccc1/C=C/c1n[nH]c2ccccc12 -US20120252789A1,3,CC(C)(C)OC(=O)N1CCN(c2cccc(Br)n2)CC1.CC1(C)CCCc2ccc(B3OC(C)(C)C(C)(C)O3)cc21>>CC(C)(C)OC(=O)N1CCN(c2cccc(-c3ccc4c(c3)C(C)(C)CCC4)n2)CC1 -US20020004511A1,2,CN1CCN(CCCN)CC1.COC(=O)c1ncc(-c2cc3nccc(Cl)c3s2)n1C>>CN1CCN(CCCNC(=O)c2ncc(-c3cc4nccc(Cl)c4s3)n2C)CC1 -US07504399B2,1,N#CC(C#N)=C(Cl)c1ccccc1.O=C(C(=O)N1CCNCC1)c1c[nH]c2ccccc12>>N#CC(C#N)=C(c1ccccc1)N1CCN(C(=O)C(=O)c2c[nH]c3ccccc23)CC1 -US05733910,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(Cl)c(Cl)c(Cl)c1>>CC(C)(C)OC(=O)Nc1cc(Cl)c(Cl)c(Cl)c1 -US20090069300A1,1,N#Cc1ccc(Cl)nc1.O=C1NCCc2cc(O)ccc21>>N#Cc1ccc(Oc2ccc3c(c2)CCNC3=O)nc1 -US07858781B2,1,CCOC(=O)c1cc2c(O)cccc2n1C(=O)OC(C)(C)C.OCc1coc2cc(F)ccc12>>CCOC(=O)c1cc2c(OCc3coc4cc(F)ccc34)cccc2n1C(=O)OC(C)(C)C -US08809376B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C#N)c4Br)ccc21.Fc1cccc(F)c1C[Zn+]>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C#N)c4Cc3c(F)cccc3F)ccc21 -US03953476,1,CCCCO.CS(=O)c1cc(C(=O)O)cc(N)c1Cl>>CCCCNc1cc(C(=O)O)cc(S(C)=O)c1Cl -US07279580B2,3,CC(C)(O)c1ccn2c(-c3ccc(F)c(Cl)c3)cnc2c1F.OB(O)c1cc2ccccc2o1>>CC(C)(O)c1ccn2c(-c3ccc(F)c(-c4cc5ccccc5o4)c3)cnc2c1F -US05310748,1,BrCCCSCCCBr.Cc1nc2ccccc2[nH]1>>Cc1nc2ccccc2n1CCCSCCCBr -US04338333,1,CC(=O)CCc1ccc(O)cc1.COC(=O)CBr>>COC(=O)COc1ccc(CCC(C)=O)cc1 -US04303663,1,Cc1cc(F)ccc1C1(CCCCl)OCCO1.O=C1NCN(c2ccccc2)C12CCNCC2>>Cc1cc(F)ccc1C1(CCCN2CCC3(CC2)C(=O)NCN3c2ccccc2)OCCO1 -US20060160803A1,3,C=CN1C(=O)c2ccccc2C1=O.Nc1cc(Br)cc(C(F)(F)F)c1>>Nc1cc(/C=C/N2C(=O)c3ccccc3C2=O)cc(C(F)(F)F)c1 -US20140309220A1,6,COC(=O)c1ccn(C(C)C)c(=O)c1>>CC(C)n1ccc(C(=O)O)cc1=O -US07473699B2,2,Cc1ncn(-c2ccc(N)cc2F)n1.O=C(Cl)OCc1ccccc1>>Cc1ncn(-c2ccc(NC(=O)OCc3ccccc3)cc2F)n1 -US20050004207A1,1,NC(=O)c1cc(Cl)ccn1.OCc1cccc(O)c1>>NC(=O)c1cc(Oc2cccc(CO)c2)ccn1 -US07217723B2,6,CC(=O)c1cc(S(=O)(=O)N(C)CC(O)c2ccc(F)cc2)c(NC(=O)OC(C)(C)C)s1>>CC(=O)c1cc(S(=O)(=O)N(C)CC(O)c2ccc(F)cc2)c(N)s1 -US20110183989A1,3,Nc1c(Cl)ccnc1Br.OB(O)C1CC1>>Nc1c(Cl)ccnc1C1CC1 -US20040014968A1,2,CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1Cl.Nc1ccc(Cl)cn1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2ccc(Cl)cn2)cc1Cl -US20020045551A1,9,CC(C)(C)OC(=O)C(C(=O)c1ccc(NS(C)(=O)=O)cc1Cl)C(=O)C1CC1>>CS(=O)(=O)Nc1ccc(C(=O)CC(=O)C2CC2)c(Cl)c1 -US20130345419A1,7,COc1ccc(OCC(=O)C[N+](=O)[O-])cc1OC>>COc1ccc(OCC(=O)CN)cc1OC -US20080132551A1,3,CCCC[Sn](CCCC)(CCCC)c1ccco1.Nc1ccccc1I>>Nc1ccccc1-c1ccco1 -US20120302541A1,7,COc1ccc(Oc2cc(-c3ccccc3)ccc2[N+](=O)[O-])cc1>>COc1ccc(Oc2cc(-c3ccccc3)ccc2N)cc1 -US20070232682A1,7,CC(C)c1c(C(=O)/C=C/c2ccc(F)c(F)c2)c2cc(O)ccc2n1Cc1ccccc1>>CC(C)c1c(C(=O)CCc2ccc(F)c(F)c2)c2cc(O)ccc2n1Cc1ccccc1 -US04247551,4,CC(=O)CCC(C)=O.NNc1nnc(N2CCOCC2)c2ccccc12>>Cc1ccc(C)n1Nc1nnc(N2CCOCC2)c2ccccc12 -US07056927B2,1,CCOC(=O)CCCBr.COc1cccc(-c2cn(Cc3c(F)cccc3C(F)(F)F)c(=O)n(C[C@H](N)CC(C)C)c2=O)c1Cl>>CCOC(=O)CCCN[C@H](CC(C)C)Cn1c(=O)c(-c2cccc(OC)c2Cl)cn(Cc2c(F)cccc2C(F)(F)F)c1=O -US04695310,2,CC1(C)Cc2cccc(S(=O)(=O)N=C=O)c2O1.Cc1cc(C2CC2)nc(N)n1>>Cc1cc(C2CC2)nc(NC(=O)NS(=O)(=O)c2cccc3c2OC(C)(C)C3)n1 -US20110178064A1,3,Brc1nccs1.C[C@H]1CN(c2ncc(B3OC(C)(C)C(C)(C)O3)cc2C=O)C[C@@H](C)O1>>C[C@H]1CN(c2ncc(-c3nccs3)cc2C=O)C[C@@H](C)O1 -US20120302567A1,2,COc1cc(OC)c(Cl)c(NC(=O)c2csc3c(N)ncnc23)c1Cl.O=C=Nc1cccc(C(F)(F)F)c1>>COc1cc(OC)c(Cl)c(NC(=O)c2csc3c(NC(=O)Nc4cccc(C(F)(F)F)c4)ncnc23)c1Cl -US20040192680A1,2,Cc1ccc(Sc2ccccc2CCC(=O)O)cc1.NCCCCO>>Cc1ccc(Sc2ccccc2CCC(=O)NCCCCO)cc1 -US04022900,2,COc1ccc(C(=O)Cl)cc1.Nc1cccc2cnccc12>>COc1ccc(C(=O)Nc2cccc3cnccc23)cc1 -US06432950B1,1,Cc1csc2nc(-c3ccno3)nc(Cl)c12.NCc1ccc(F)cc1>>Cc1csc2nc(-c3ccno3)nc(NCc3ccc(F)cc3)c12 -US20110136834A1,1,CC1(C)O[C@@H]2[C@@H](CO)O[C@@H](n3ccc4c(Cl)ncnc43)[C@@H]2O1.N[C@H]1CCc2ccccc21>>CC1(C)O[C@@H]2[C@@H](CO)O[C@@H](n3ccc4c(N[C@H]5CCc6ccccc65)ncnc43)[C@@H]2O1 -US20140121113A1,6,COC(=O)c1cc2cc(C(F)(F)F)ccc2s1>>O=C(O)c1cc2cc(C(F)(F)F)ccc2s1 -US20100216746A1,2,CC(C)(C)OC(=O)Nc1ccc2[nH]c(C(=O)O)cc2c1.N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1>>CC(C)(C)OC(=O)Nc1ccc2[nH]c(C(=O)NCc3ccc(Cl)c(Oc4cc(Cl)cc(C#N)c4)c3F)cc2c1 -US20090156593A1,5,N#CC1(c2ccccc2)CCC(=O)CC1.OCCO>>N#CC1(c2ccccc2)CCC2(CC1)OCCO2 -US20100331312A1,7,COc1cccc(C(C)C[N+](=O)[O-])c1>>COc1cccc(C(C)CN)c1 -US06239131B1,6,CCOC(=O)c1cccc(NC(=O)NC2CN(C(=O)C3CCCCC3)c3ccc(C)cc3N(CC(=O)c3ccccc3C)C2=O)c1>>Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(NC(=O)Nc1cccc(C(=O)O)c1)CN2C(=O)C1CCCCC1 -US04428870,3,C#Cc1ccccc1.CCC(C)=O>>CCC(C)(O)C#Cc1ccccc1 -US20110237791A1,1,CCOC(=O)c1ccc(C2CC2)c(O)n1.CI>>CCOC(=O)c1ccc(C2CC2)c(OC)n1 -US20080293716A1,2,CC(C)N.O=C(O)c1ccc(-c2ccncc2)s1>>CC(C)NC(=O)c1ccc(-c2ccncc2)s1 -US20080318911A1,8,CC(C)(O)CC=CC1(C2=CC[C@H]3[C@@H](O)CCC[C@@]23C)CC1>>CC(C)(O)CC=CC1(C2=CC[C@H]3C(=O)CCC[C@@]23C)CC1 -US08026247B2,9,Nc1nc(Cl)cc(Oc2ccc3c(C(=O)Nc4cccc(C(F)(F)F)c4)cccc3c2)n1>>Nc1nccc(Oc2ccc3c(C(=O)Nc4cccc(C(F)(F)F)c4)cccc3c2)n1 -US20040077854A1,2,C1CC2(CCN1)OCCO2.C=CCN(CC=C)Cc1ccc(S(=O)(=O)Cl)s1>>C=CCN(CC=C)Cc1ccc(S(=O)(=O)N2CCC3(CC2)OCCO3)s1 -US20130178459A1,3,COc1ccc2[nH]c(=O)c3sccc3c2c1Br.C[C@H](NC(=O)OC(C)(C)C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc([C@H](C)NC(=O)OC(C)(C)C)cc1 -US05849911,2,CC[C@H](C)[C@H](NC(=O)OC)C(=O)O.COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(N)Cc1ccc(-c2nnn(C(C)(C)c3ccccc3)n2)cc1)C(C)(C)C>>CC[C@H](C)[C@H](NC(=O)OC)C(=O)NN(Cc1ccc(-c2nnn(C(C)(C)c3ccccc3)n2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C -US08637529B2,9,Nc1nc(Cl)c2cn[nH]c2n1>>Nc1ncc2cn[nH]c2n1 -US08232289B2,3,CB1OB(C)OB(C)O1.CCOC(=O)c1nn(-c2ncccc2Cl)cc1C=O>>CCOC(=O)c1nn(-c2ncccc2C)cc1C=O -US20100331306A1,1,CNC(=O)c1c(-c2ccccc2)c(C(C)N)nc2ccc(F)cc12.N#Cc1c(N)ncnc1Cl>>CNC(=O)c1c(-c2ccccc2)c(C(C)Nc2ncnc(N)c2C#N)nc2ccc(F)cc12 -US06867218B2,1,C/C(=C\CO)c1ccc(-c2ccco2)cc1.CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC>>CCOC(=O)[C@H](Cc1ccc(OC/C=C(\C)c2ccc(-c3ccco3)cc2)cc1)OCC -US20090264445A1,9,COC(=O)[C@H](CC(=O)CC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>COC(=O)[C@H](CC(C)=O)NC(=O)OCc1ccccc1 -US20150225345A1,3,C#Cc1cccc(F)c1.COC(=O)c1ccc(Br)cn1>>COC(=O)c1ccc(C#Cc2cccc(F)c2)cn1 -US20150057272A1,2,Cc1cnc(N)s1.O=C(O)c1cccc2[nH]c(-c3cnccc3C(F)(F)F)nc12>>Cc1cnc(NC(=O)c2cccc3[nH]c(-c4cnccc4C(F)(F)F)nc23)s1 -US20060217424A1,1,CN.COc1cc(C=O)ccc1Oc1cc(Cl)ccc1C#N>>CNCc1ccc(Oc2cc(Cl)ccc2C#N)c(OC)c1 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.O=C(Cl)c1ccno1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)c4ccno4)nc3cc21 -US20110275797A1,1,C1CNC1.COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(OCCBr)ccc1OCc1ccccc1>>COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(OCCN2CCC2)ccc1OCc1ccccc1 -US20020198197A1,2,Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)on1.Cc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(C)cc3NC(=O)OC(C)(C)C)c2)on1 -US05646173,4,COc1ccc2c(c1)C(=O)C(CC=O)CC2.C[C@H](O)CN>>COc1ccc2c(c1)-c1c(ccn1CC(C)O)CC2 -US20090306133A1,2,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1.O=C(O)c1ccnc(Br)c1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2ccnc(Br)c2)CC1 -US07812040B2,2,CN(C[C@@H]1C[C@H](O)C1)C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CN(C[C@@H]1C[C@H](OS(C)(=O)=O)C1)C(=O)OC(C)(C)C -US20140206681A1,2,Cc1cc(Br)ccc1C(=O)O.Nc1cc(C(F)(F)F)ccn1>>Cc1cc(Br)ccc1C(=O)Nc1cc(C(F)(F)F)ccn1 -US20040034234A1,8,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1SC(F)(F)F.OO>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1S(=O)C(F)(F)F -US08557816B2,8,COc1ccc2c(Sc3ccccc3)ccnc2c1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2c(S(=O)c3ccccc3)ccnc2c1 -US05821240,1,C1CCNC1.OC1CCN(c2ncc3ncnc(Nc4ccc(F)c(Cl)c4)c3n2)CC1>>Fc1ccc(Nc2ncnc3cnc(N4CCC(N5CCCC5)CC4)nc23)cc1Cl -US04965273,1,CCOC(=O)c1cn(C(C)(C)C)c2nc(Cl)c(F)cc2c1=O.O=C(N1C2CCC1CNC2)C(F)(F)F>>CCOC(=O)c1cn(C(C)(C)C)c2nc(N3CC4CCC(C3)N4C(=O)C(F)(F)F)c(F)cc2c1=O -US20140364433A1,1,Cc1ccc(-c2ccccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)n1.Clc1ccc(Br)nc1>>Cc1ccc(-c2ccccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(Cl)cn2)n1 -US07825256B2,4,N#CCN(CCCNCc1ccc2c(c1)OCO2)c1nc(-n2ccnc2)ns1.[N-]=[N+]=[N-]>>c1cn(-c2nsc(N(CCCNCc3ccc4c(c3)OCO4)Cc3nnn[nH]3)n2)cn1 -US20030069392A1,7,CCCCCCCCCCCCCCNC(=O)CCCCCCCCCCCCC>>CCCCCCCCCCCCCCNCCCCCCCCCCCCCC -US20100144787A1,1,CC(C)(C)OC(=O)CBr.Cc1c(Cc2ccc(Br)cc2)c(=O)[nH]c2c(F)ccc(O)c12>>Cc1c(Cc2ccc(Br)cc2)c(=O)[nH]c2c(F)ccc(OCC(=O)OC(C)(C)C)c12 -US06841553B2,7,CCOC(=O)Cc1nc(-c2ccccc2)[nH]c1C>>Cc1[nH]c(-c2ccccc2)nc1CCO -US08791102B2,2,O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@H]1C[C@@H](O)CN1.O=C(O)Cn1cncn1>>O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@H]1C[C@@H](O)CN1C(=O)Cn1cncn1 -US05449682,7,C=CCc1cc(CO)ccc1O>>CCCc1cc(CO)ccc1O -US20150266881A1,6,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1cccc(C(=O)NC2CCOCC2)c1>>N[C@@H]1C[C@H]1c1cccc(C(=O)NC2CCOCC2)c1 -US07560569B2,2,C[C@@H](N)c1ccccc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>C[C@@H](NC(=O)C12CCC(NCC(=O)N3C[C@@H](F)C[C@H]3C#N)(CC1)CC2)c1ccccc1 -US20100041891A1,7,O=Cc1cc2ncnc(Cl)c2s1>>OCc1cc2ncnc(Cl)c2s1 -US07910595B2,1,CC(C)(C)OC(=O)Nc1ccc(O)cc1.O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(F)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccc(C(=O)Nc3ccc(C(F)(F)F)cc3)cc2[N+](=O)[O-])cc1 -US20060161001A1,6,CC(C)(C)OC(=O)N1CCC(Nc2nccc(N3CCCc4cnc(-c5ccccc5)cc43)n2)CC1>>c1ccc(-c2cc3c(cn2)CCCN3c2ccnc(NC3CCNCC3)n2)cc1 -US06271223B1,1,Cn1ccc2c1C(=O)CN(CCCBr)S2(=O)=O.Fc1ccc(N2CCNCC2)cc1>>Cn1ccc2c1C(=O)CN(CCCN1CCN(c3ccc(F)cc3)CC1)S2(=O)=O -US20140329863A1,3,CN(C)c1ccc(Br)cn1.Cc1cccc(Nc2nc(-c3ccc(B4OC(C)(C)C(C)(C)O4)cc3)cs2)n1>>Cc1cccc(Nc2nc(-c3ccc(-c4ccc(N(C)C)nc4)cc3)cs2)n1 -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.COC(=O)c1nn(-c2cccc(Br)c2)c2ccnc(NC3CC3)c12>>COC(=O)c1nn(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)c2ccnc(NC3CC3)c12 -US20100120739A1,2,NN.O=C(O)Cc1c(F)cc2ncc(Br)cc2c1F>>NNC(=O)Cc1c(F)cc2ncc(Br)cc2c1F -US07960369B2,3,CCOc1ccccc1B(O)O.COC(=O)CCc1ccc(OCc2cccc(Br)c2)cc1>>CCOc1ccccc1-c1cccc(COc2ccc(CCC(=O)OC)cc2)c1 -US08492437B2,2,Nc1ccc(O)cc1.O=C(Cl)c1ccc(Cl)c(Cl)c1>>O=C(Nc1ccc(O)cc1)c1ccc(Cl)c(Cl)c1 -US06432950B1,1,CCc1cc2c(Cl)nc(Cl)nc2s1.COc1ccc(CN)cc1OC>>CCc1cc2c(NCc3ccc(OC)c(OC)c3)nc(Cl)nc2s1 -US20020156311A1,1,Cc1c(N)cccc1[N+](=O)[O-].O=Cc1ccc(F)cc1F>>Cc1c(NCc2ccc(F)cc2F)cccc1[N+](=O)[O-] -US09096600B2,7,COc1c(C(C)=O)cc(Cl)c(F)c1Br>>COc1c(C(C)O)cc(Cl)c(F)c1Br -US08436002B2,1,CC(C)(C)OC(=O)N1CCC(c2nc(I)c(I)[nH]2)CC1.ClCCN1CCCC1>>CC(C)(C)OC(=O)N1CCC(c2nc(I)c(I)n2CCN2CCCC2)CC1 -US07834009B2,7,CC(C)=CCC1CN(Cc2ccc(F)cc2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O>>CC(C)CCC1CN(Cc2ccc(F)cc2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O -US20090281100A1,3,Brc1ccncc1.CC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CC(=O)Nc1ccc(-c2ccncc2)cc1 -US07709471B2,7,COc1cc(C(=O)O)c(Cl)cc1[N+](=O)[O-]>>COc1cc(C(=O)O)c(Cl)cc1N -US20100190824A1,1,C1COCCN1.O=Cc1cccc(Br)n1>>O=Cc1cccc(N2CCOCC2)n1 -US20150183763A1,2,Nc1cc(-c2cccc(COC(C(F)(F)F)C(F)(F)F)c2)n(-c2ccccc2)n1.O=C1C[C@H](C(=O)O)CN1>>O=C1C[C@H](C(=O)Nc2cc(-c3cccc(COC(C(F)(F)F)C(F)(F)F)c3)n(-c3ccccc3)n2)CN1 -US06294547B1,6,Clc1c2c(nc3ccccc13)CCN(Cc1ccccc1)C2>>Clc1c2c(nc3ccccc13)CCNC2 -US20070244125A1,2,C1CCC(N2CCNCC2)C1.CCOC(=O)c1cc2cc(C(=O)O)ccc2[nH]1>>CCOC(=O)c1cc2cc(C(=O)N3CCN(C4CCCC4)CC3)ccc2[nH]1 -US20050075499A1,3,CCCC[Sn](C#Cc1ccccc1)(CCCC)CCCC.COC(=O)c1cc(NC(C)=O)cc(NC(C)=O)c1Br>>COC(=O)c1cc(NC(C)=O)cc(NC(C)=O)c1C#Cc1ccccc1 -US20150045378A1,1,CCOC(=O)CC(c1cc(OCc2cnc(-c3cc(OC)ccc3F)c(O)c2)ncn1)C1CC1.OCCC(F)(F)F>>CCOC(=O)CC(c1cc(OCc2cnc(-c3cc(OC)ccc3F)c(OCCC(F)(F)F)c2)ncn1)C1CC1 -US20120225869A1,1,CC(C)c1ccc(-c2nc3c(-c4ccccc4)n[nH]c3c(=O)n2-c2ccc(Cl)cc2)cc1.CN(C)C(=O)Cl>>CC(C)c1ccc(-c2nc3c(-c4ccccc4)nn(C(=O)N(C)C)c3c(=O)n2-c2ccc(Cl)cc2)cc1 -US08759359B2,3,CON(C)C(=O)c1nc2cccc(C)n2c1Br.OB(O)c1cc(F)cc(F)c1>>CON(C)C(=O)c1nc2cccc(C)n2c1-c1cc(F)cc(F)c1 -US20150111866A1,3,COc1ncc(Cl)cc1Br.CSc1ncc(B2OC(C)(C)C(C)(C)O2)c(CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)n1>>COc1ncc(Cl)cc1-c1cnc(SC)nc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C -US20080255083A1,1,CC1(O)CCNCC1.O=c1cc(OCc2ccccn2)ccn1CCc1ccc(CBr)cc1>>CC1(O)CCN(Cc2ccc(CCn3ccc(OCc4ccccn4)cc3=O)cc2)CC1 -US20020143020A1,6,CC[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)OCc1c(F)cccc1F>>CC[C@@H]1CNCCN1C(=O)OCc1c(F)cccc1F -US05744479,2,CC(C)C(=O)Cl.CC(C)C(=O)Nc1ccc(-c2sc3c(c2CN(C)Cc2ccccc2)c(=O)c(O)cn3Cc2c(F)cccc2F)cc1>>CC(C)C(=O)Nc1ccc(-c2sc3c(c2CN(C)Cc2ccccc2)c(=O)c(OC(=O)C(C)C)cn3Cc2c(F)cccc2F)cc1 -US04886810,1,C[C@H]1CNC[C@H]1N.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)c(F)c2c1=O>>C[C@H]1CN(c2c(F)c(F)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C[C@H]1N -US07902373B2,6,CC(C)(C)OC(=O)N1CCC(NC(=O)c2ccc(-c3cccc(F)c3)nc2)C(c2ccc(F)cc2)C1>>O=C(NC1CCNCC1c1ccc(F)cc1)c1ccc(-c2cccc(F)c2)nc1 -US07745641B2,2,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccc(C(F)(F)F)cc3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21 -US06100399,4,CC(=O)c1c(-c2ccc(F)cc2)ncn1C1CCN(Cc2ccccc2)CC1.COC(OC)N(C)C.N=C(N)N>>Nc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCN(Cc3ccccc3)CC2)n1 -US20090215817A1,6,COC(=O)c1ccc(C)c(-c2nnc3ccc(CCc4ccc(F)cc4F)cn23)c1>>Cc1ccc(C(=O)O)cc1-c1nnc2ccc(CCc3ccc(F)cc3F)cn12 -US20130172339A1,3,O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(Br)s1.OB(O)c1cccc(C(F)(F)F)c1>>O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(-c2cccc(C(F)(F)F)c2)s1 -US20090111805A1,1,CCC(C)C=O.Clc1ccc2c(c1)C1(CCNCC1)CN2c1ncnc2[nH]ccc12>>CCC(C)CN1CCC2(CC1)CN(c1ncnc3[nH]ccc13)c1ccc(Cl)cc12 -US08273773B2,3,CCCC[Sn](/C=C/c1cc(-c2cc(F)cnc2OC)cc(C(C)(C)C)c1OC)(CCCC)CCCC.Nc1ccc(I)nc1>>COc1ncc(F)cc1-c1cc(/C=C/c2ccc(N)cn2)c(OC)c(C(C)(C)C)c1 -US20080220487A1,7,CC(=O)O[C@H](C)CCc1ccccc1>>C[C@@H](O)CCc1ccccc1 -US08921404B2,2,CC1CCN(C(=O)Cl)CC1.Oc1noc2ncccc12>>CC1CCN(C(=O)Oc2noc3ncccc23)CC1 -US08048905B2,2,CC(C)C(=O)Cl.COC(=O)c1cc(N)cc(-c2ccc(C)cn2)c1F>>COC(=O)c1cc(NC(=O)C(C)C)cc(-c2ccc(C)cn2)c1F -US07691837B2,3,C=O.Cc1ccc(-c2ccc(Cl)cc2)n1-c1ccc(Cl)cc1.FC(F)(F)c1cccc(N2CCNCC2)c1>>Cc1c(CN2CCN(c3cccc(C(F)(F)F)c3)CC2)cc(-c2ccc(Cl)cc2)n1-c1ccc(Cl)cc1 -US06426345B1,3,CCOP(=O)(Cc1ccccc1)OCC.O=Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(/C=C/c2ccccc2)c1 -US20140336185A1,2,CCCCCCCOc1ccc(Cc2nc3cc(CNCC(=O)OC(C)(C)C)ccc3[nH]2)cc1.COc1ccc(CC(=O)Nc2ccc(C(=O)O)cc2)cc1>>CCCCCCCOc1ccc(Cc2nc3cc(CN(CC(=O)OC(C)(C)C)C(=O)c4ccc(NC(=O)Cc5ccc(OC)cc5)cc4)ccc3[nH]2)cc1 -US20080242675A1,9,CN1CCN(c2cc(CC(=O)OC(C)(C)C)ccn2)CC1.N>>CN1CCN(c2cc(CC(N)=O)ccn2)CC1 -US20110086853A1,2,CC(F)(F)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1.CCNC(=O)c1cc[nH]c1>>CCNC(=O)c1ccn(S(=O)(=O)c2ccc3c(c2)nc(C(C)(F)F)n3CC2CCOCC2)c1 -US05998433,2,COC(=O)c1cc2c(o1)CNCC2.O=C(O)c1ccc(C(=O)c2ccccc2)cc1>>COC(=O)c1cc2c(o1)CN(C(=O)c1ccc(C(=O)c3ccccc3)cc1)CC2 -US20110212945A1,3,Nc1ccc(Br)nc1.OB(O)c1ccccc1>>Nc1ccc(-c2ccccc2)nc1 -US06355662B1,2,Cc1ccccc1N=C=O.Nc1ccc(CC(=O)O)cc1>>Cc1ccccc1NC(=O)Nc1ccc(CC(=O)O)cc1 -US20050272931A1,2,CC(C)(C)c1ccc(/C=C/C(=O)O)cc1.Cn1ccc2cc(N)ccc21>>Cn1ccc2cc(NC(=O)/C=C/c3ccc(C(C)(C)C)cc3)ccc21 -US08273747B2,3,CCOc1ccc(Br)cc1C=O.N#Cc1ccc(B(O)O)cc1>>CCOc1ccc(-c2ccc(C#N)cc2)cc1C=O -US06339093B1,1,Clc1cc(N2CCc3ccccc3C2)c2ccccc2n1.OC[C@H]1CCCN1>>OC[C@H]1CCCN1c1cc(N2CCc3ccccc3C2)c2ccccc2n1 -US05610185,2,O=C(O)C=Cc1ccc(F)c(F)c1.OCCc1ccccc1>>O=C(C=Cc1ccc(F)c(F)c1)OCCc1ccccc1 -US20140200231A1,2,O=C(Cl)OCCCCl.c1ccc2c(c1)CC(Nc1ncc3c(n1)CNC3)C2>>O=C(OCCCCl)N1Cc2cnc(NC3Cc4ccccc4C3)nc2C1 -US04204991,6,C=C(NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)N(C(=O)CN(C)C(=O)OC(C)(C)C)[N+](=O)[O-])C(C)C)[C@@H](C)CC)C(=O)OC>>C=C(NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)N(C(=O)CN(C)C(=O)OC(C)(C)C)[N+](=O)[O-])C(C)C)[C@@H](C)CC)C(=O)O -US20070287698A1,2,CCOC(=O)CC1CCNCC1.Cc1ccc2c(c1)C(c1ccccc1Cl)CN(CC(=O)O)C(=O)C2CC(C)C>>CCOC(=O)CC1CCN(C(=O)CN2CC(c3ccccc3Cl)c3cc(C)ccc3C(CC(C)C)C2=O)CC1 -US05478835,2,Cc1ccc2c(c1)C(C(=O)O)c1ccccc1CO2.Cc1cccc(Cl)c1N>>Cc1ccc2c(c1)C(C(=O)Nc1c(C)cccc1Cl)c1ccccc1CO2 -US20110021493A1,1,CC(C)(C)OC(=O)N1CCc2c(sc3ncc(C#N)c(Cl)c23)C1.Nc1ccc2c(cnn2Cc2cccc(F)c2)c1>>CC(C)(C)OC(=O)N1CCc2c(sc3ncc(C#N)c(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)C1 -US20060229312A1,1,CC(N)=O.Cc1ccc2c(N3CCN(CCc4cc(Br)ccc4F)CC3)cccc2n1>>CC(=O)Nc1ccc(F)c(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 -US20120184732A1,2,CC(C)(C)OC(=O)NCC(=O)O.Nc1ccccc1C(=O)c1cnc2ccccc2c1>>CC(C)(C)OC(=O)NCC(=O)Nc1ccccc1C(=O)c1cnc2ccccc2c1 -US09156829B2,7,O=C1CCCC1Cc1cc(C(F)(F)F)ccn1>>OC1CCCC1Cc1cc(C(F)(F)F)ccn1 -US05290796,4,BrCCCCBr.CC1CCN(C)C(C)C1(C)CCN>>CC1CCN(C)C(C)C1(C)CCN1CCCC1 -US08367831B2,1,NCC1OCCO1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>O=[N+]([O-])c1ccc(Cl)nc1NCC1OCCO1 -US04100277,9,CC1(C)OCCC(=O)c2ccccc2NC1=O.NO>>CC1(C)OCCC(=NO)c2ccccc2NC1=O -US04027026,2,CN=C=O.NCCSCc1ccccn1>>CNC(=O)NCCSCc1ccccn1 -US06319916B1,2,O=CO.c1ccc2c(c1)CNCCO2>>O=CN1CCOc2ccccc2C1 -US20080176862A1,3,C#Cc1ccnc(C)c1.Fc1ccc(I)cc1Br>>Cc1cc(C#Cc2ccc(F)c(Br)c2)ccn1 -US05919433,2,CC(Br)C(=O)O.NCC(=O)OCc1ccccc1>>CC(Br)C(=O)NCC(=O)OCc1ccccc1 -US20120202785A1,7,Cn1cc(Nc2cc(F)ccc2[N+](=O)[O-])cn1>>Cn1cc(Nc2cc(F)ccc2N)cn1 -US20080214553A1,1,CC(C)NC(=O)Cn1c(-c2ccc(F)c(Cl)c2)nc2ccc(O)cc2c1=O.ClCCCBr>>CC(C)NC(=O)Cn1c(-c2ccc(F)c(Cl)c2)nc2ccc(OCCCCl)cc2c1=O -US20090209522A1,2,CCOC(=O)c1csc(Oc2cccc(C(C)(C)C)c2)n1.COc1nc(NCCCN2CCOCC2)nc(OC)c1N>>COc1nc(NCCCN2CCOCC2)nc(OC)c1NC(=O)c1csc(Oc2cccc(C(C)(C)C)c2)n1 -US08969388B1,9,Cc1c(C(=O)Nc2ccc(Oc3ccnc(C(N)=O)c3Cl)cc2F)c(=O)n(-c2ccccc2)n1C>>Cc1c(C(=O)Nc2ccc(Oc3ccnc(N)c3Cl)cc2F)c(=O)n(-c2ccccc2)n1C -US20090137609A1,3,C#CC(O)(CC)CC.CCC(CC)(c1ccc(Br)c(C)c1)c1cc(C)c(O)c(C)c1>>CCC(O)(C#Cc1ccc(C(CC)(CC)c2cc(C)c(O)c(C)c2)cc1C)CC -US08183262B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.FC(F)(F)c1cccc(-c2cc(C(F)(F)F)nc(-c3cccc(Br)c3)n2)c1>>Nc1ccc(-c2cccc(-c3nc(-c4cccc(C(F)(F)F)c4)cc(C(F)(F)F)n3)c2)cn1 -US05753664,1,CCc1cccc2nc(S)n(C)c(=O)c12.O=C(c1ccc(CBr)cc1)c1ccc([N+](=O)[O-])cc1>>CCc1cccc2nc(SCc3ccc(C(=O)c4ccc([N+](=O)[O-])cc4)cc3)n(C)c(=O)c12 -US20090181966A1,1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(O)cc2)c2ccccc21.CCOC(=O)C(F)Br>>CCOC(=O)[C@H](F)Oc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)CC2C)cc1 -US06130239,3,C#CCC(NC(C)=O)C(=O)OCC.Cc1nc[nH]c1/C=C1\C(=O)Nc2ccc(F)c(I)c21>>CCOC(=O)C(CC#Cc1c(F)ccc2c1/C(=C/c1[nH]cnc1C)C(=O)N2)NC(C)=O -US08895749B2,2,COc1cc(-c2ccncc2)ccc1C(=O)O.NC1CCc2ccccc21>>COc1cc(-c2ccncc2)ccc1C(=O)NC1CCc2ccccc21 -US20140303164A1,2,Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@@H](N)Cc3cc(F)cc(F)c3)c21.O=C(O)Cn1nc(C(F)(F)F)c2c1CCCC2>>Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)Cn3nc(C(F)(F)F)c4c3CCCC4)c21 -US20020045635A1,1,CCI.Cc1nc(N2CCc3nc(N)sc3CC2)c([N+](=O)[O-])c(=O)[nH]1>>CCn1c(C)nc(N2CCc3nc(N)sc3CC2)c([N+](=O)[O-])c1=O -US20140350030A1,7,COC(=O)C12CCCC(NC(=O)OC(C)(C)C)(CC1)C2>>CC(C)(C)OC(=O)NC12CCCC(CO)(CC1)C2 -US08389555B2,6,CCOC(CCCNC(=O)N1CCN(c2ccccc2)CC1)OCC>>O=CCCCNC(=O)N1CCN(c2ccccc2)CC1 -US20140212903A1,7,O=[N+]([O-])c1ccc(N(CCO)CCO)cc1>>Nc1ccc(N(CCO)CCO)cc1 -US08765743B2,3,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.CCn1ncc2c(NC(=O)c3cccc(C)n3)cc(Br)cc21>>CCn1ncc2c(NC(=O)c3cccc(C)n3)cc(-c3cccc4[nH]ccc34)cc21 -US08063046B2,3,CCOP(=O)(Cc1ccc(OC(F)(F)F)cc1)OCC.N#Cc1ccc(Br)c(C=O)c1>>N#Cc1ccc(Br)c(C=Cc2ccc(OC(F)(F)F)cc2)c1 -US20030088096A1,1,CC1CCN(c2nc(NC#N)nc(Cl)c2-c2ccccc2)CC1.CI>>CC1CCN(c2nc(N(C)C#N)nc(Cl)c2-c2ccccc2)CC1 -USRE030574,1,CC1(C)CCC(C)(CO)O1.Cc1ccccc1CCl>>Cc1ccccc1COCC1(C)CCC(C)(C)O1 -US05681504,3,C#Cc1ccc([C@@H]2CC[C@@H](CCC)CC2)cc1.CCCCOC(=O)[C@@H]1OC(c2ccc(Br)cc2)O[C@H]1C(=O)OCCCC>>CCCCOC(=O)[C@@H]1OC(c2ccc(C#Cc3ccc([C@@H]4CC[C@@H](CCC)CC4)cc3)cc2)O[C@H]1C(=O)OCCCC -US20090233924A1,1,COCCOc1cc2ncnc(Cl)c2cc1OC.COc1cc(O)ccc1CC(=O)Nc1ccc(N(C)C)cn1>>COCCOc1cc2ncnc(Oc3ccc(CC(=O)Nc4ccc(N(C)C)cn4)c(OC)c3)c2cc1OC -US20100298343A1,1,Clc1ccc2ccccc2n1.Nc1ccc(S)cc1>>Nc1ccc(Sc2ccc3ccccc3n2)cc1 -US05639780,9,COc1ccc2c(c1)c(CC(C)CC(=O)O)c(C)n2Cc1ccc(Br)cc1.N>>COc1ccc2c(c1)c(CC(C)CC(N)=O)c(C)n2Cc1ccc(Br)cc1 -US20040122244A1,7,COC1=C(OC)C(=O)C(Cc2ccc(C(=O)Nc3ccc(S(=O)(=O)C(F)(F)F)cc3)c(OC(C)=O)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(C(=O)Nc3ccc(S(=O)(=O)C(F)(F)F)cc3)c(O)c2)=C(C)C1=O -US20140171405A1,3,CN1CCN(c2cc(B3OC(C)(C)C(C)(C)O3)ccn2)CC1.COc1cc(OC)c(F)c(-c2ncc3c(I)n[nH]c3n2)c1F>>COc1cc(OC)c(F)c(-c2ncc3c(-c4ccnc(N5CCN(C)CC5)c4)n[nH]c3n2)c1F -US20120208798A1,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CN(C)CCCl>>CN(C)CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1 -US20120208798A1,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CN(C)CCCl>>CN(C)CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1 -US20090074890A1,1,C[Si](C)(C)CCOCNC(=O)c1n[nH]c(-c2cccc(-c3ccccc3O)c2)n1.Fc1ccc(CBr)cc1>>C[Si](C)(C)CCOCNC(=O)c1n[nH]c(-c2cccc(-c3ccccc3OCc3ccc(F)cc3)c2)n1 -US20040192708A1,9,Cc1nn(C)c(Cl)c1S(=O)(=O)N(C)c1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1>>Cc1nn(C)cc1S(=O)(=O)N(C)c1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1 -US20040242645A1,7,Cc1cccc(C2=NCCN2C)c1[N+](=O)[O-]>>Cc1cccc(C2=NCCN2C)c1N -US08507491B2,3,Cc1ccc(N)cc1B1OC(C)(C)C(C)(C)O1.Fc1cnc(Cl)c(F)c1>>Cc1ccc(N)cc1-c1ncc(F)cc1F -US20050171131A1,1,CC(=O)c1ccncc1.Nc1ccc(-c2c(N)nc(N)nc2COCc2ccccc2)cc1>>CC(Nc1ccc(-c2c(N)nc(N)nc2COCc2ccccc2)cc1)c1ccncc1 -US20090247526A1,2,CC(=O)N1CCC(C(=O)O)CC1.CNOC>>CON(C)C(=O)C1CCN(C(C)=O)CC1 -US07632840B2,1,COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1C=O.N#CCCNCC(=O)O>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(CCC#N)CC(=O)O -US20090270435A1,6,COc1c(Cl)ccc2c1C(=O)CC1(CCN(C(=O)OC(C)(C)C)CC1)O2>>COc1c(Cl)ccc2c1C(=O)CC1(CCNCC1)O2 -US20120129855A1,7,COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4cccc([N+](=O)[O-])c34)ccc2F)CC1>>COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4cccc(N)c34)ccc2F)CC1 -US20050137240A1,2,CCC(=O)Cl.NC1CCC(CNc2nc3c(s2)CCOc2ccccc2-3)CC1>>CCC(=O)NC1CCC(CNc2nc3c(s2)CCOc2ccccc2-3)CC1 -US20120071489A1,2,CC(C)(C)c1ccccc1N1CCNCC1.O=C(O)C1CCCO1>>CC(C)(C)c1ccccc1N1CCN(C(=O)C2CCCO2)CC1 -US20060257543A1,1,CCC(C)I.Oc1ccc(NC(=S)NCc2ccco2)cc1>>CCC(C)Oc1ccc(NC(=S)NCc2ccco2)cc1 -US20120322788A1,7,CC(C)(C)OC(=O)N1CCC(O)(CC#N)CC1>>CC(C)(C)OC(=O)N1CCC(O)(CCN)CC1 -US07803822B2,2,CCNC(=O)c1ccc(-n2nnc(C(=O)O)c2C)c(OCc2ccccc2)c1.NC1CC1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2C)c(OCc2ccccc2)c1 -US20140343053A1,1,C1COCCN1.O=c1n(CCc2ccc3ccccc3n2)nc2cccc(Br)n12>>O=c1n(CCc2ccc3ccccc3n2)nc2cccc(N3CCOCC3)n12 -US04087432,2,Nc1ncc(C(F)F)cc1[N+](=O)[O-].O=C(OC(=O)C(F)F)C(F)F>>O=C(Nc1ncc(C(F)F)cc1[N+](=O)[O-])C(F)F -US20090176854A1,7,CC(=O)c1ccc(C(=O)NCCC(=O)OC(C)(C)C)cc1>>CC(O)c1ccc(C(=O)NCCC(=O)OC(C)(C)C)cc1 -US20080306096A1,6,Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cc(OCc3ccccc3)ccc12>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cc(O)ccc12 -US05336436,8,COCCOCOCCCCCCCCCO>>COCCOCOCCCCCCCCC=O -US08415345B2,7,N#Cc1nccc(-c2sc(N3CCOCC3)nc2-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)n1>>NCc1nccc(-c2sc(N3CCOCC3)nc2-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)n1 -US04369058,2,CC(C)O.COc1cc(C)nc(NC(=O)NS(=O)(=O)c2cccc(N=C=O)c2)n1>>COc1cc(C)nc(NC(=O)NS(=O)(=O)c2cccc(NC(=O)OC(C)C)c2)n1 -US20150018356A1,4,COC(=O)C1CCCCCC1=O.COC(=O)c1cc(N)cc(F)c1>>COC(=O)c1cc(F)cc2[nH]c3c(c(=O)c12)CCCCC3 -US20090036450A1,1,Cc1nc(CCl)oc1C(C)(C)O[SiH2]C(C)(C)C.OCC(F)(F)F>>Cc1nc(COCC(F)(F)F)oc1C(C)(C)O[SiH2]C(C)(C)C -US06538015B1,2,CC(C)n1nc(CN)c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1.CS(=O)(=O)Cl>>CC(C)n1nc(CNS(C)(=O)=O)c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1 -US08791102B2,2,CC(=O)c1ccc(N2CCN(CC(=O)O)CC2)cc1.N[C@@H](COCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1>>CC(=O)c1ccc(N2CCN(CC(=O)N[C@@H](COCc3ccccc3)C(=O)Nc3ccc(Oc4ccc(F)cc4)cc3)CC2)cc1 -US20040006229A1,3,CC1CC(OS(=O)(=O)C(F)(F)F)=CCN1C(=O)Oc1ccccc1.OB(O)c1ccc2ccccc2c1>>CC1CC(c2ccc3ccccc3c2)=CCN1C(=O)Oc1ccccc1 -US20100113539A1,8,CCC(CC)CNc1cccc(C(O)CCNC(=O)OC(C)(C)C)c1>>CCC(CC)CNc1cccc(C(=O)CCNC(=O)OC(C)(C)C)c1 -US20100016396A1,6,COc1ccc(COc2cc(Oc3c(C=O)c(C)nn3C)c(Cl)cc2Cl)cc1>>Cc1nn(C)c(Oc2cc(O)c(Cl)cc2Cl)c1C=O -US20040121965A1,6,CCOC(=O)/C(C)=C/[C@@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1)C(C)(C)c1ccc(OC)cc1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)(C)c1ccccc1)C(C)(C)c1ccc(OC)cc1 -US08153658B2,6,COC(=O)c1csc(N2CCC(CN(C(=O)OC(C)(C)C)[C@H](C)c3cccc4ccccc34)C(c3ccccc3)C2)n1>>C[C@H](c1cccc2ccccc12)N(CC1CCN(c2nc(C(=O)O)cs2)CC1c1ccccc1)C(=O)OC(C)(C)C -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)C=Cc1ccc(Cl)cc1>>CC(C)C[C@H]1CN(C(=O)C=Cc2ccc(Cl)cc2)[C@@H](CC(C)C)C(=O)N1 -US20070088033A1,6,O=c1cc(OCc2ccccc2)ccn1Cc1cccc(F)c1>>O=c1cc(O)ccn1Cc1cccc(F)c1 -US20090137609A1,6,CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)cc2)c(C)c1>>CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)O)cc2)c(C)c1 -US07582673B2,7,COc1ccc(Br)cc1S(=O)(=O)Nc1ccc(F)cc1[N+](=O)[O-]>>COc1ccc(Br)cc1S(=O)(=O)Nc1ccc(F)cc1N -US08716296B2,3,CCOc1ccccc1B(O)O.Nc1cc(Cl)ncn1>>CCOc1ccccc1-c1cc(N)ncn1 -US05180838,3,Brc1cccc2ccccc12.Brc1cccs1>>c1csc(-c2cccc3ccccc23)c1 -US20030109527A1,7,O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)N2CCC2)c1O>>Nc1ccc(Cl)c(S(=O)(=O)N2CCC2)c1O -US06103910,1,C=C(C)C.O=C(O)c1ccc[nH]1>>CC(C)(C)OC(=O)c1ccc[nH]1 -US20060241302A1,1,CSCCN.Fc1ccc(F)c(C(Sc2ccc(Cl)cc2)c2cc(Cl)ncc2Cl)c1>>CSCCNc1cc(C(Sc2ccc(Cl)cc2)c2cc(F)ccc2F)c(Cl)cn1 -US20040009995A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1c2ccccc2C(=O)N1CCCCc1nn[nH]n1>>O=C1c2ccccc2C(=O)N1CCCCc1nnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US20130150400A1,2,CN.Cc1c(C(=O)O)oc2ccccc12>>CNC(=O)c1oc2ccccc2c1C -US20130079323A1,1,CCc1cc2c(O)nc(Sc3cnc(C#N)c(F)c3)nc2[nH]1.OC1CNC1>>CCc1cc2c(N3CC(O)C3)nc(Sc3cnc(C#N)c(F)c3)nc2[nH]1 -US08426420B2,6,CCOC(=O)N1CCN(C(=O)[C@H](CCOCc2ccccc2)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1>>CCOC(=O)N1CCN(C(=O)[C@H](CCO)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1 -US20120122842A1,1,CC(C)(C)OC(=O)NCC1CNC1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)OC(=O)NCC1CN(c2ccc([N+](=O)[O-])cc2)C1 -US07384931B2,2,O=C(O)C[C@@H]1Cc2ccc3[nH]ncc3c2CN(Cc2ccccc2)C1=O.O=C1Nc2ccccc2CC1N1CCNCC1>>O=C1Nc2ccccc2CC1N1CCN(C(=O)C[C@@H]2Cc3ccc4[nH]ncc4c3CN(Cc3ccccc3)C2=O)CC1 -US20090264445A1,6,COC(=O)[C@H](CC1CCCCC1)N1CC(Oc2ccc(C)nc2)=CC1=O>>Cc1ccc(OC2=CC(=O)N([C@@H](CC3CCCCC3)C(=O)O)C2)cn1 -US04797347,2,C=C(C)C(=O)Cl.O=C1c2ccccc2C(=O)c2cc(O)ccc21>>C=C(C)C(=O)Oc1ccc2c(c1)C(=O)c1ccccc1C2=O -US20140142085A1,1,COC(=O)c1n[nH]c2c1COC2.NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)CCl)ccc1F>>COC(=O)c1nn(CC(=O)N[C@@H](Cc2cc(F)cc(F)c2)c2ncccc2-c2ccc(F)c(C(N)=O)c2)c2c1COC2 -US05990105,9,N.Nc1ccc(S(=O)(=O)c2cc(Br)nc(Br)c2)cc1>>Nc1ccc(S(=O)(=O)c2cc(N)nc(Br)c2)cc1 -US20150175563A1,9,N.O=C(O)c1sccc1Br>>NC(=O)c1sccc1Br -US08084463B2,2,Nc1ccon1.O=C(Br)CBr>>O=C(CBr)Nc1ccon1 -US20090099181A1,3,C#Cc1cncc(C(=O)N=[S@@](C)(=O)c2ccccc2)c1.O=C(O)c1ccc(I)cc1>>C[S@@](=O)(=NC(=O)c1cncc(C#Cc2ccc(C(=O)O)cc2)c1)c1ccccc1 -US07192982B2,9,CO[C@@H](Cc1ccc(C#CCOc2ccc(C(=O)c3ccc(F)cc3)cc2)cc1)C(=O)O.NO>>CO[C@@H](Cc1ccc(C#CCOc2ccc(C(=NO)c3ccc(F)cc3)cc2)cc1)C(=O)O -US07157430B2,2,CC(C)C[C@H](N)C(=O)N[C@H](C=O)CC(=NNC(N)=O)OC(C)(C)C.O=C(O)CNc1cccc2ccccc12>>CC(C)C[C@H](NC(=O)CNc1cccc2ccccc12)C(=O)N[C@H](C=O)CC(=NNC(N)=O)OC(C)(C)C -US20070015794A1,6,CNC(=O)Nc1cc(CNc2ccccc2C(=O)Nc2ccc3nn(CCOC)cc3c2)ccn1>>CNC(=O)Nc1cc(CNc2ccccc2C(=O)Nc2ccc3nn(CCO)cc3c2)ccn1 -US20150250767A1,1,CC(C)(C)S(N)=O.COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C(=O)c1nc2cc(C#N)ccc2o1>>COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C(=NS(=O)C(C)(C)C)c1nc2cc(C#N)ccc2o1 -US20140142085A1,6,CCOC(=O)C(CC(F)(F)F)n1cnc2cc(C)c(C)cc21>>Cc1cc2ncn(C(CC(F)(F)F)C(=O)O)c2cc1C -US05998436,1,NC1CNC1.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(F)cc1Cl>>Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(N4CC(N)C4)c(Cl)c32)c(F)cc1Cl -US04183932,7,Clc1ccc2c(c1)c(-c1ccccc1)nc1nncn12>>Clc1ccc2c(c1)C(c1ccccc1)Nc1nncn1-2 -US04742057,7,CC(=O)N1CCC(c2c[nH]c3ccccc23)CC1>>CC(=O)N1CCC(C2CNc3ccccc32)CC1 -US09156827B2,7,COc1ccc2c(c1C#CCN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O>>COc1ccc2c(c1/C=C\CN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O -US08017602B2,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C(O)CCOCCc1cccc(Br)c1>>Cn1cc(-c2cccc(CCOCCC(=O)O)c2)cn1 -US20060252790A1,2,CCn1ncc2c(NC3CCOCC3)c(C(=O)O)cnc21.NC1(CO)CCOCC1>>CCn1ncc2c(NC3CCOCC3)c(C(=O)NC3(CO)CCOCC3)cnc21 -US08859572B2,6,COc1c(OCCOCCNC(=O)OC(C)(C)C)ccc2c1N=C(NC(=O)c1cccnc1)N1CCN=C21>>COc1c(OCCOCCN)ccc2c1N=C(NC(=O)c1cccnc1)N1CCN=C21 -US20110028467A1,2,O=C(O)c1cc(Cl)nc(Cl)c1.c1cc2c(cn1)NCCO2>>O=C(c1cc(Cl)nc(Cl)c1)N1CCOc2ccncc21 -US20080132504A1,3,COc1ccc(B(O)O)cc1.Cc1ccc(Br)cc1[N+](=O)[O-]>>COc1ccc(-c2ccc(C)c([N+](=O)[O-])c2)cc1 -US20100179194A1,2,CC(=O)Cl.NCc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1>>CC(=O)NCc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1 -US20080064691A1,6,CC(C)(C)[Si](C)(C)OC[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1>>O=C(N[C@@H]1Cc2ccccc2[C@H]1CO)c1cc2cc(Cl)sc2[nH]1 -US07179934B2,7,CCC[C@@H](C)[C@@H](C)/C(=C/C(=O)OCC)NC(C)=O>>CCC[C@@H](C)[C@@H](C)[C@@H](CC(=O)OCC)NC(C)=O -US04296199,1,O=C(O)c1cc(O)c2ccccc2c1O.OCCBr>>O=C(O)c1cc(OCCBr)c2ccccc2c1O -US07498333B2,1,BrCCC1OCCO1.Cc1nsc2nc(C(N)C(C)C)n(Cc3ccccc3)c(=O)c12>>Cc1nsc2nc(C(NCCC3OCCO3)C(C)C)n(Cc3ccccc3)c(=O)c12 -US06403601B1,2,CNCC(CCO)c1ccc(F)c(F)c1.O=C(Cl)c1cccc2c1CCCC2>>CN(CC(CCO)c1ccc(F)c(F)c1)C(=O)c1cccc2c1CCCC2 -US08003648B2,1,O=C(C[C@@H](c1ccc(O)cc1)c1ccon1)N1C(=O)OC[C@@H]1Cc1ccccc1.OCc1ccc(Br)c(OC(F)(F)F)c1>>O=C(C[C@@H](c1ccc(OCc2ccc(Br)c(OC(F)(F)F)c2)cc1)c1ccon1)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20110070595A1,2,CCNc1c(Br)cnc(Cl)c1N.N#CCC(=O)O>>CCNc1c(Br)cnc(Cl)c1NC(=O)CC#N -US06602878B1,1,CC(C)(C)OC(=O)[C@H](CCO)NC(=O)OCc1ccccc1.COC(=O)CCc1cccc(O)c1>>COC(=O)CCc1cccc(OCCC(NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)c1 -US08552208B2,1,CCOC(=O)[C@@H](N)Cc1ccccc1.O=Cc1ccccc1>>CCOC(=O)[C@H](Cc1ccccc1)NCc1ccccc1 -US08614226B2,3,CN(C)CCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(Br)c2)c2cccnc2n1>>CN(C)CCCn1cc(-c2cncc(-c3cc(-c4cc(Cl)ccc4F)nc4ncccc34)c2)cn1 -US07153848B2,2,CN(C)S(N)(=O)=O.O=C(O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(O)Cc1ccccc1-3>>CN(C)S(=O)(=O)NC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(O)Cc1ccccc1-3 -US08431563B2,1,C[C@H]1COCCN1C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1.OCC(O)(c1ccc(Br)cc1)C(F)(F)F>>C[C@H]1COCCN1C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(O)(CO)C(F)(F)F)cc1 -US20100256097A1,1,CC(C)(O)COCc1cccc(Br)n1.CS(=O)(=O)c1ccc(-c2cc(C(N)=O)c(N)s2)cc1>>CC(C)(O)COCc1cccc(Nc2sc(-c3ccc(S(C)(=O)=O)cc3)cc2C(N)=O)n1 -US04159331,2,FC(F)(F)c1cc(N2CCNCC2)cc(C(F)(F)F)c1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>O=[N+]([O-])c1ccc(S(=O)(=O)N2CCN(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)cc1 -US20040014802A1,2,CCCC(=O)Cl.Nc1n[nH]c2cc(C(F)(F)F)ccc12>>CCCC(=O)Nc1n[nH]c2cc(C(F)(F)F)ccc12 -US04611080,3,C=C(Cl)Cl.O=C(Cl)c1cc(F)c(F)cc1F>>O=C(C=C(Cl)Cl)c1cc(F)c(F)cc1F -US20100190831A1,7,CC1(C)Cc2cc(-c3ccccc3)cc(C=O)c2O1>>CC1(C)Cc2cc(-c3ccccc3)cc(CO)c2O1 -US05180723,2,CNC1CCCCC1.Cc1ccc(C(=O)Cl)cc1>>Cc1ccc(C(=O)N(C)C2CCCCC2)cc1 -US06075029,1,CC(C)(C)C(=O)OCCl.Cc1nc2c([nH]1)c(=O)[nH]c(=O)n2Cc1ccco1>>Cc1nc2c(c(=O)[nH]c(=O)n2Cc2ccco2)n1COC(=O)C(C)(C)C -US08871288B2,2,CC1CCC(C(C)C)C(N)C1.O=C(Cl)c1ccccc1>>CC(C)[C@H]1CC[C@H](C)C[C@H]1NC(=O)c1ccccc1 -US08871288B2,2,CC1CCC(C(C)C)C(N)C1.O=C(Cl)c1ccccc1>>CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1NC(=O)c1ccccc1 -US06353006B1,1,CC(C)CBr.CCC(C)[C@H]1CSC(=Nc2ccc3c(c2)CCC3=O)N1>>CCC(C)[C@H]1CSC(=Nc2ccc3c(c2)CCC3=O)N1CC(C)C -US20100210649A1,6,CC(C)(C)OC(=O)NCCCOc1cccc(-n2ncc(Br)c(Br)c2=O)c1>>NCCCOc1cccc(-n2ncc(Br)c(Br)c2=O)c1 -US06348461B1,6,CCOC(=O)c1nc2cc(-n3cccc3)c(C(F)(F)F)cc2[nH]c1=O>>O=C(O)c1nc2cc(-n3cccc3)c(C(F)(F)F)cc2[nH]c1=O -US07935722B2,1,CC(C)C(=O)NC1CCc2[nH]c3ccc(Br)cc3c2C1.Fc1cccc(CBr)c1>>CC(C)C(=O)NC1CCc2c(c3cc(Br)ccc3n2Cc2cccc(F)c2)C1 -US07314888B1,2,CCOC(=O)[C@@H]1C[C@@H](OC2CCCCO2)CN1C(=O)OCc1ccccc1.CNOC>>CON(C)C(=O)[C@@H]1C[C@@H](OC2CCCCO2)CN1C(=O)OCc1ccccc1 -US20100298221A1,1,O=Cc1ccc(-c2ccc(C(F)(F)F)cc2)nc1Cl.Oc1ccccc1Cl>>O=Cc1ccc(-c2ccc(C(F)(F)F)cc2)nc1Oc1ccccc1Cl -US20060063828A1,6,COC(=O)c1ccc(C(=O)Cc2cc(-c3cccnc3)ccc2OC)cc1>>COc1ccc(-c2cccnc2)cc1CC(=O)c1ccc(C(=O)O)cc1 -US20070049604A1,1,COc1ccc(N2CCN(CCN)CC2)cc1.Cc1ccc(-c2cc(C=O)nn2C(C)(C)C)cc1>>COc1ccc(N2CCN(CCNCc3cc(-c4ccc(C)cc4)n(C(C)(C)C)n3)CC2)cc1 -US20050171174A1,6,CC(C)(C)[Si](C)(C)O[C@H]1CN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)[C@]2(Cc2ccc(C#N)cc2)C1>>N#Cc1ccc(C[C@@]23C[C@@H](O)CN2C(=O)N(c2cc(Cl)cc(Cl)c2)C3=O)cc1 -US20110092490A1,2,C1COCCN1.Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)Cl>>Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N1CCOCC1 -US06974813B2,2,CCOC(=O)c1cnn(-c2cc(C(=O)O)ccc2Cl)c1C1CC1.CN>>CCOC(=O)c1cnn(-c2cc(C(=O)NC)ccc2Cl)c1C1CC1 -US20140213586A1,1,COc1cccc(N)c1.COc1ncccc1C=O>>COc1cccc(N=Cc2cccnc2OC)c1 -US20140128386A1,7,O=[N+]([O-])c1ncc(Cl)cc1OCc1ncccc1F>>Nc1ncc(Cl)cc1OCc1ncccc1F -US20100240677A1,1,COC(=O)c1cnc(Cl)c([N+](=O)[O-])c1.C[S-]>>COC(=O)c1cnc(SC)c([N+](=O)[O-])c1 -US20100261755A1,3,CC(C)(C)c1ccc(B2OC(C)(C)C(C)(C)O2)s1.COC(=O)c1ccnc(Cl)c1>>COC(=O)c1ccnc(-c2ccc(C(C)(C)C)s2)c1 -US05216165,6,COC(=O)c1ccc(Nc2ccnc3cc(Cl)ccc23)cc1>>O=C(O)c1ccc(Nc2ccnc3cc(Cl)ccc23)cc1 -US05726126,2,CC(=O)Cl.Nc1ccc(Cl)cc1F>>CC(=O)Nc1ccc(Cl)cc1F -US20120202783A1,6,COC(=O)c1c(F)cccc1-c1ncccn1>>O=C(O)c1c(F)cccc1-c1ncccn1 -US06613775B1,1,CCOC(=O)c1nc2c(N)cc(C)cn2c1C.Cc1cccc(C)c1CCl>>CCOC(=O)c1nc2c(NCc3c(C)cccc3C)cc(C)cn2c1C -US20110124642A1,2,Nn1nc(-c2ccccc2)c2cc(F)ccc2c1=O.O=C(O)Cc1cc(F)cc(F)c1>>O=C(Cc1cc(F)cc(F)c1)Nn1nc(-c2ccccc2)c2cc(F)ccc2c1=O -US20020082426A1,2,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O.OC1CNCC1SCc1ccccc1>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N1CC(O)C(SCc2ccccc2)C1 -US09126984B2,2,CCC(=O)Cl.O=S(=O)(c1ccccc1)n1cc(-c2cnn(C3CCNCC3)c2)c2ccc(F)cc21>>CCC(=O)N1CCC(n2cc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cn2)CC1 -US08071595B2,6,CCOC(=O)c1ccc2nonc2c1>>O=C(O)c1ccc2nonc2c1 -US20120209001A1,1,CC(C)(C)n1nc(CCC=O)cc1-c1ccccc1.Cc1ccc(N2CCNCC2)c(C)c1>>Cc1ccc(N2CCN(CCCc3cc(-c4ccccc4)n(C(C)(C)C)n3)CC2)c(C)c1 -US20040198755A1,9,BrCc1ccc2nsnc2c1.[C-]#N>>N#CCc1ccc2nsnc2c1 -US20080146624A1,9,NO.O=C(Nc1ccc(F)c(Cl)c1)c1cocn1>>ON=C(Nc1ccc(F)c(Cl)c1)c1cocn1 -US20150073011A1,6,C=C[C@@H](CO[Si](C)(C)C(C)(C)C)N1C(=O)c2ccccc2C1=O>>C=C[C@H](N)CO[Si](C)(C)C(C)(C)C -US20100274022A1,1,BrCCBr.O=Cc1cccc(O)c1>>O=Cc1cccc(OCCBr)c1 -US20100278835A1,1,CC(C)(C)OC(=O)NCc1ccc2c(c1)nc(CO)n2CCCC(F)(F)F.O=C1Nc2ccccc2CN1C1CC1>>CC(C)(C)OC(=O)NCc1ccc2c(c1)nc(CN1C(=O)N(C3CC3)Cc3ccccc31)n2CCCC(F)(F)F -US20040142981A1,2,CN(c1ccc(Cl)cc1)S(=O)(=O)c1cccc(C(=O)Nc2ccc(Br)cc2C(=O)O)c1.CS(N)(=O)=O>>CN(c1ccc(Cl)cc1)S(=O)(=O)c1cccc(C(=O)Nc2ccc(Br)cc2C(=O)NS(C)(=O)=O)c1 -US04820834,2,Cn1c(C(=O)O)cc2ccccc21.NC1N=C(c2ccccc2F)c2ccccc2NC1=O>>Cn1c(C(=O)NC2N=C(c3ccccc3F)c3ccccc3NC2=O)cc2ccccc21 -US04229465,2,CC(=O)OC(C)=O.N#Cc1c[nH]cc1-c1ccccc1>>CC(=O)n1cc(C#N)c(-c2ccccc2)c1 -US07893099B2,3,N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccc(Br)cc3Cl)C[C@H]2C(=O)N2CCC(F)(F)C2)CC1.OB(O)c1ccnc(Cl)c1>>N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccc(-c4ccnc(Cl)c4)cc3Cl)C[C@H]2C(=O)N2CCC(F)(F)C2)CC1 -US05461060,1,COCCl.Cc1c[nH]c(=O)[nH]c1=O>>COCn1cc(C)c(=O)[nH]c1=O -US20110257151A1,2,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(N)c1.O=C(O)c1ccccn1>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(NC(=O)c2ccccn2)c1 -US06248739B1,3,CON(C)C(C)=O.Fc1ccc(CN2CCOCC2)cc1Br>>CC(=O)c1cc(CN2CCOCC2)ccc1F -US20110021506A1,1,O=C(CCl)N1CCN(c2ccc(C(F)(F)F)cc2)CC1.O=[N+]([O-])c1ccc(N[C@@H]2CC[C@@H](O)CC2)cc1C(F)(F)F>>O=C(CO[C@@H]1CC[C@@H](Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1)N1CCN(c2ccc(C(F)(F)F)cc2)CC1 -US20120214767A1,2,CS(=O)(=O)Cl.OCc1ccc2c(c1)CCc1c-2noc1C1CCC(c2ccc(Cl)cc2)CC1>>CS(=O)(=O)OCc1ccc2c(c1)CCc1c-2noc1C1CCC(c2ccc(Cl)cc2)CC1 -US20120022056A1,6,C=CCc1cccc2c1OCc1c(C(=O)OCC)ncn1-2>>C=CCc1cccc2c1OCc1c(C(=O)O)ncn1-2 -US20150152113A1,2,NNc1nncc(N2CCC3(CC2)C(=O)Oc2ccccc23)c1Cl.O=C(Cl)CC(F)(F)F>>O=C(CC(F)(F)F)NNc1nncc(N2CCC3(CC2)C(=O)Oc2ccccc23)c1Cl -US04940710,1,CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21.CN1CCN(CC2CNCCN2)CC1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(CN4CCN(C)CC4)C3)cc21 -US04380638,6,COC1=NS(=O)(=O)N=C1NCCSCc1nc[nH]c1C>>Cc1[nH]cnc1CSCCNC1=NS(=O)(=O)N=C1O -US20110135671A1,1,C1CN(CC2CC2)CCN1.CCCCNc1nc(N)c2nc(OC)n(CCCCl)c2n1>>CCCCNc1nc(N)c2nc(OC)n(CCCN3CCN(CC4CC4)CC3)c2n1 -US20040058956A1,6,O[C@@H](COCc1ccccc1)Cc1ncc[nH]1>>OC[C@H](O)Cc1ncc[nH]1 -US20070270475A1,1,CI.COc1cc(C(=O)N2[C@@H](c3ncc(C)s3)[C@@H](CO)C[C@@]2(Cc2cscn2)C(=O)OC(C)(C)C)ccc1C(C)(C)C>>COC[C@H]1C[C@@](Cc2cscn2)(C(=O)OC(C)(C)C)N(C(=O)c2ccc(C(C)(C)C)c(OC)c2)[C@H]1c1ncc(C)s1 -US05395837,1,C[S-].Clc1ccnc(Oc2ccccc2)n1>>CSc1ccnc(Oc2ccccc2)n1 -US08049015B2,2,CCNCc1cc(C(F)(F)F)ccc1-c1cncc(CC(=O)OCC)c1.O=C(O)CCc1cccnc1>>CCOC(=O)Cc1cncc(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)CCc2cccnc2)c1 -US20100298573A1,3,C#C[Si](C)(C)C.O=c1oc2cc(-n3nc4ccc5ccccc5c4n3)ccc2cc1Br>>C[Si](C)(C)C#Cc1cc2ccc(-n3nc4ccc5ccccc5c4n3)cc2oc1=O -US20080039625A1,7,O=[N+]([O-])c1ccccc1C=C(Cl)Cl>>Nc1ccccc1C=C(Cl)Cl -US06376503B1,1,FC(F)(F)CI.N#Cc1ccccc1N1CCC(NCCNC(=O)N2C(=O)OC[C@@H]2c2ccc(F)c(F)c2)CC1>>N#Cc1ccccc1N1CCC(N(CCNC(=O)N2C(=O)OC[C@@H]2c2ccc(F)c(F)c2)CC(F)(F)F)CC1 -US20020082254A1,2,NN1CCc2ccccc2C1.O=C(Cl)Oc1ccc(C(=O)OCc2ccccc2)cc1>>O=C(NN1CCc2ccccc2C1)Oc1ccc(C(=O)OCc2ccccc2)cc1 -US04996358,1,CC(C)C[C@@H](O)C(=O)O.O=[N+]([O-])c1ccc(CBr)cc1>>CC(C)C[C@@H](O)C(=O)OCc1ccc([N+](=O)[O-])cc1 -US05157026,9,CCCCc1nc2ncc(Br)c(C)c2[nH]1>>CCCCc1nc2nccc(C)c2[nH]1 -US20150038438A1,1,CC(C)(C)OC(=O)Nc1ccc2c(c1)OCCCC2=O.CI>>CN(C(=O)OC(C)(C)C)c1ccc2c(c1)OCCCC2=O -US04374748,9,N#C[Cu].Oc1ccc(-c2ccc(Br)cc2)cc1>>N#Cc1ccc(-c2ccc(O)cc2)cc1 -US20040082619A1,8,CCCCn1c2c(cc(CO)c1=O)CCCC2>>CCCCn1c2c(cc(C=O)c1=O)CCCC2 -US06552054B1,2,COc1cccc2oc(C(=O)O)cc(=O)c12.Nc1ccc(CC2SC(=O)NC2=O)cc1>>COc1cccc2oc(C(=O)Nc3ccc(CC4SC(=O)NC4=O)cc3)cc(=O)c12 -US20130338140A1,1,CC(C)(C)OC(=O)N[C@H](CCI)c1ccc(Cl)c(Cl)c1.C[S-]>>CSCC[C@@H](NC(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1 -US08022062B2,5,COc1cccc(CN)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cccc(CNC(=O)C(F)(F)F)c1 -US04197411,3,C1=CCC=C1.CC(C=O)=CCCl>>CC1(C=O)C2C=CC(C2)C1CCl -US20080255083A1,2,COC(=O)c1ccc(CCO)s1.CS(=O)(=O)Cl>>COC(=O)c1ccc(CCOS(C)(=O)=O)s1 -US20130053381A1,1,CCC(O)c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)(F)F.CCCC(=O)Cl>>CCCC(=O)N(n1c(=O)[nH]c2cc(C(F)(F)F)c(C(O)CC)cc2c1=O)S(C)(=O)=O -US06800619B2,2,CCNCC.O=C(O)CC(NC(=O)C1CCCCN1C(=O)N1c2ccccc2Sc2ccccc21)C(=O)CF>>CCN(CC)C(=O)CC(NC(=O)C1CCCCN1C(=O)N1c2ccccc2Sc2ccccc21)C(=O)CF -US20080004312A1,6,COC(=O)C1(Cc2ccccc2)CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(Cc2ccccc2)CCNCC1 -US20150065482A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1cc(N)n[nH]1>>COC(=O)c1cc(NC(=O)OC(C)(C)C)n[nH]1 -US08022208B2,6,CCOC(=O)C1CCN(CCn2cccc(-c3ccc(C(=O)OCc4ccccc4)cc3)c2=O)CC1>>CCOC(=O)C1CCN(CCn2cccc(-c3ccc(C(=O)O)cc3)c2=O)CC1 -US20030191110A1,9,CCN1CCCC[C@H]1C(=O)O>>CCN1CCCC[C@H]1C=O -US08247556B2,7,N#Cc1ccnc2[nH]ncc12>>NCc1ccnc2[nH]ncc12 -US20070082912A1,1,CCOC(=O)c1cncc(-n2c(C)ccc2-c2cc(Cl)ccc2O)c1.Clc1ccc(CBr)cc1Cl>>CCOC(=O)c1cncc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(Cl)c(Cl)c2)c1 -US20040147612A1,7,CC(C)S(=O)(=O)NCC(C)(O)c1ccc(N(CC#N)Cc2ccccc2)cc1>>CC(C)S(=O)(=O)NCC(C)(O)c1ccc(N(CCN)Cc2ccccc2)cc1 -US20080090834A1,1,Cc1ccc(-n2cc(-c3ccccn3)nc2-c2ccc(I)cc2)cn1.c1cc2[nH]ccc2cn1>>Cc1ccc(-n2cc(-c3ccccn3)nc2-c2ccc(-n3ccc4cnccc43)cc2)cn1 -US05223623,2,COC(=O)c1ccc(N(C)S(C)(=O)=O)cc1.NCC1CN(c2ccccc2)CCN1Cc1ccccc1>>CN(c1ccc(C(=O)NCC2CN(c3ccccc3)CCN2Cc2ccccc2)cc1)S(C)(=O)=O -US20070249670A1,2,CC(C)c1cc(C(=O)OC(C)(C)C)c(N)s1.O=C=Nc1c(Cl)cccc1Cl>>CC(C)c1cc(C(=O)OC(C)(C)C)c(NC(=O)Nc2c(Cl)cccc2Cl)s1 -US20110294779A1,2,C1CNC1.Cn1ncc(C(=O)O)c1C(=O)Nc1cc2nc(-c3ccccc3)cn2cc1Br>>Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1cc2nc(-c3ccccc3)cn2cc1Br -US04470976,2,CC(=O)OC(C)=O.Nc1ccc(S[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1>>CC(=O)Nc1ccc(S[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1 -US06964983B2,7,Cc1cc(C=Cc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)ccc1OCC(=O)O>>Cc1cc(CCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)ccc1OCC(=O)O -US05304532,1,CCOC(=O)c1ccccc1O.Clc1ccc(Cl)nc1>>CCOC(=O)c1ccccc1Oc1ccc(Cl)cn1 -US20100222324A1,6,CN(C)C1(c2cccs2)CCN(CCNC(=O)OC(C)(C)C)CC1>>CN(C)C1(c2cccs2)CCN(CCN)CC1 -US20090227799A1,6,COC(=O)c1ccc(CCF)nc1N>>Nc1nc(CCF)ccc1C(=O)O -US20050020574A1,9,N.O=[N+]([O-])c1c(Cl)ccnc1Cl>>Nc1ccnc(Cl)c1[N+](=O)[O-] -US05723497,1,CCCCC(CC)COCCCCCCCCCCO.ClCC1CO1>>CCCCC(CC)COCCCCCCCCCCOCC1CO1 -US20140303139A1,3,C[C@H](Nc1cc(C(N)=O)nc(Cl)n1)C(N)=O.OB(O)c1ccc(O)cc1>>C[C@H](Nc1cc(C(N)=O)nc(-c2ccc(O)cc2)n1)C(N)=O -US20110263584A1,3,C[C@@H](c1ccc(Br)cc1)N1CC[C@](CCCO)(c2ccc(F)cc2)OC1=O.Cc1cccc(B(O)O)n1>>Cc1cccc(-c2ccc([C@H](C)N3CC[C@](CCCO)(c4ccc(F)cc4)OC3=O)cc2)n1 -US20140275528A1,1,Cn1c(=O)c2c(nc(Br)n2CCc2ccc(Cl)cc2)n(C)c1=O.Oc1cccc(CN2CCOCC2)c1>>Cn1c(=O)c2c(nc(Oc3cccc(CN4CCOCC4)c3)n2CCc2ccc(Cl)cc2)n(C)c1=O -US20110178064A1,8,C[C@H]1CN(c2nc(F)ccc2CO)C[C@@H](C)O1>>C[C@H]1CN(c2nc(F)ccc2C=O)C[C@@H](C)O1 -US20090018156A1,7,CCn1cc(-c2ccnc3[nH]cc(Br)c23)c(-c2cccc([N+](=O)[O-])c2)n1>>CCn1cc(-c2ccnc3[nH]cc(Br)c23)c(-c2cccc(N)c2)n1 -US06753432B2,10,CC/C(=C\C(=O)OC)OC.O=C1CCC(=O)N1Br>>COC(=O)/C=C(/OC)C(C)Br -US06593480B2,2,Nc1cccc(Br)c1.O=CO>>O=CNc1cccc(Br)c1 -US04544747,1,CCBr.Cc1c(N)cccc1Cl>>CCNc1cccc(Cl)c1C -US04112095,2,CC(=O)OC(C)=O.Nc1cccc(-c2ccc3nncn3n2)c1>>CC(=O)Nc1cccc(-c2ccc3nncn3n2)c1 -US20080167314A1,2,Cc1cc(-c2nc3cccnn3c2-c2ccnc(N)c2)ccc1F.O=C(Cl)c1ccncc1>>Cc1cc(-c2nc3cccnn3c2-c2ccnc(NC(=O)c3ccncc3)c2)ccc1F -US20080269233A1,6,CO[C@]1(c2ccccc2)CCN(C(=O)OC(C)(C)C)C[C@@H]1OCc1ccccc1>>CO[C@]1(c2ccccc2)CCN(C(=O)OC(C)(C)C)C[C@@H]1O -US20060046999A1,8,CCSc1c(C(=O)c2ccc(F)cc2)ccc(=O)n1-c1c(Cl)cccc1Cl.O=C(OO)c1cccc(Cl)c1>>CCS(=O)c1c(C(=O)c2ccc(F)cc2)ccc(=O)n1-c1c(Cl)cccc1Cl -US20040259843A1,6,CC1(NC(=O)OCc2ccccc2)CCN(c2nccc(C(F)(F)F)n2)CC1>>CC1(N)CCN(c2nccc(C(F)(F)F)n2)CC1 -US08008307B2,6,CO[C@H]1Cc2ccccc2[C@H]1NC(=O)OC(C)(C)C>>CO[C@H]1Cc2ccccc2[C@H]1N -US20130172556A1,1,CCC=O.CCc1cc(C)cc(CC)c1C(=O)C(=O)N(C)N>>CCC=NN(C)C(=O)C(=O)c1c(CC)cc(C)cc1CC -US04780477,1,CC(C)N(CCCl)C(C)C.COc1ccc2c(c1)C(=O)C(=O)N2>>COc1ccc2c(c1)C(=O)C(=O)N2CCN(C(C)C)C(C)C -US08765940B2,1,CC1(C)CNc2cc(N3CCOCC3)cnc21.Cc1c(N2CCOC(C)(C)C2)nc2cc(F)cc(F)c2c1Cl>>Cc1c(N2CCOC(C)(C)C2)nc2cc(F)cc(F)c2c1N1CC(C)(C)c2ncc(N3CCOCC3)cc21 -US20100249179A1,4,COC(=O)c1cccc(N)c1N.COc1ccc(C(=O)O)cc1>>COC(=O)c1cccc2[nH]c(-c3ccc(OC)cc3)nc12 -US20090227570A1,2,Nc1ccc2nc(NC3CCc4cc(F)ccc43)ccc2c1.O=C(O)CN1CCOCC1>>O=C(CN1CCOCC1)Nc1ccc2nc(NC3CCc4cc(F)ccc43)ccc2c1 -US20120165346A1,3,CCn1cc(C2(c3cccc(Br)c3)N=C(N)c3c(F)cccc32)cc(C)c1=O.OB(O)c1cncnc1>>CCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)c3c(F)cccc32)cc(C)c1=O -US20100273797A1,3,C1COCCN1.C=O.CC(C)(C)c1ccc(O)c([N+](=O)[O-])c1>>CC(C)(C)c1cc(CN2CCOCC2)c(O)c([N+](=O)[O-])c1 -US20100004269A1,2,COC(=O)c1ccc(CN)nc1Nc1ccc([Si](C)(C)C)cc1F.O=CO>>COC(=O)c1ccc(CNC=O)nc1Nc1ccc([Si](C)(C)C)cc1F -US08013186B2,1,CC(C)(C)C[C@H](N)C12OCC(C)(CO1)CO2.O=CC(F)(F)c1ccccn1>>CC(C)(C)C[C@H](N=CC(F)(F)c1ccccn1)C12OCC(C)(CO1)CO2 -US04971993,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=C(OCc1ccccc1)[C@@H]1CCCN1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1 -US08778937B2,1,Cc1nc2c(Br)cc(N3CCOCC3)cc2[nH]1.Clc1cccc(CBr)c1Cl>>Cc1nc2c(Br)cc(N3CCOCC3)cc2n1Cc1cccc(Cl)c1Cl -US20090281092A1,1,CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21.Nc1cc(F)ccc1F>>CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Nc3cc(F)ccc3F)ncc21 -US20090048286A1,3,CCOC(=O)COc1c(C(=O)OC)sc2cc(Br)ccc12.COc1ccccc1B(O)O>>CCOC(=O)COc1c(C(=O)OC)sc2cc(-c3ccccc3OC)ccc12 -US07211577B2,1,CNC.CS(=O)(=O)OCc1cc(-c2ccc(S(C)(=O)=O)cc2)nn(CC2CC2)c1=O>>CN(C)Cc1cc(-c2ccc(S(C)(=O)=O)cc2)nn(CC2CC2)c1=O -US20120259123A1,2,CC(C)(C)c1ccc(CN)cc1.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)c1ccc(CNS(=O)(=O)c2ccccc2)cc1 -US20100048570A1,2,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCSC1C(=O)O)Cc1cc(F)c(F)cc1F.CCOC(=O)C(Oc1ccc2c(c1)CNCC2)C(C)C>>CCOC(=O)C(Oc1ccc2c(c1)CN(C(=O)C1SCCN1C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)CC2)C(C)C -US20030125370A1,6,CN(C(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C1CC1>>CN(C(=O)[C@@H]1CCCN1)C1CC1 -US20110200586A1,10,Cc1ccc(C(C)(C)O)cc1C(F)(F)F.O=C1CCC(=O)N1Br>>CC(C)(O)c1ccc(CBr)c(C(F)(F)F)c1 -US20060229236A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(OCc1ccccc1)C(=O)CCCCC[C@H](N)C(=O)O>>CC(OCc1ccccc1)C(=O)CCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O -US08138189B2,1,Cc1cc(C(O)(C(C)c2ccc(O)cc2Cl)C(F)(F)F)cn(C)c1=O.O=Cc1ccc(F)c(C(F)(F)F)c1>>Cc1cc(C(O)(C(C)c2ccc(Oc3ccc(C=O)cc3C(F)(F)F)cc2Cl)C(F)(F)F)cn(C)c1=O -US07732618B2,1,CCCc1nc2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C.FC(F)(F)c1cccc(CBr)c1>>CCCc1nc2cc(N(Cc3cccc(C(F)(F)F)c3)S(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C -US06399811B1,3,CC(=O)CCCC#N.[Mg+]C1CCCC1>>CC(O)(CCCC#N)C1CCCC1 -US20130096113A1,7,N[C@@H]1CCC[C@H](C(=O)O)C1>>N[C@@H]1CCC[C@H](CO)C1 -US05789415,3,CCOC(=O)C1(c2cccs2)CC=CC1.CN(C)C=O>>CCOC(=O)C1(c2ccc(C=O)s2)CC=CC1 -US20100113502A1,1,CCCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CNCC2.O=C1CCOCC1>>CCCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCOCC1)CC2 -US06815439B2,7,CCOC(=O)Cc1ccncc1[N+](=O)[O-]>>CCOC(=O)Cc1ccncc1N -US20110059957A1,3,C#Cc1csc(C2CCN(C(=O)OC(C)(C)C)CC2)n1.CC(C)(C)OC(=O)NNC(=O)Cc1ccc(Br)cc1>>CC(C)(C)OC(=O)NNC(=O)Cc1ccc(C#Cc2csc(C3CCN(C(=O)OC(C)(C)C)CC3)n2)cc1 -US20080166593A1,1,Cc1ccc(-c2c3ccccc3c(Br)c3ccccc23)c2ccccc12.Oc1ccccc1>>Cc1ccc(-c2c3ccccc3c(Oc3ccccc3)c3ccccc23)c2ccccc12 -US05488115,3,O=C[C@@H](OCc1ccccc1)[C@H]1COC2(CCCCC2)O1.[Mg+]c1ccccc1>>OC(c1ccccc1)[C@@H](OCc1ccccc1)[C@H]1COC2(CCCCC2)O1 -US20030162795A1,3,Brc1cc2nccc(Nc3ccc4[nH]ccc4c3)c2s1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2cc3nccc(Nc4ccc5[nH]ccc5c4)c3s2)cc1 -US05633276,1,CCOC(CBr)OCC.Nc1cccc2c1CCO2>>CCOC(CNc1cccc2c1CCO2)OCC -US20040192686A1,1,CCCN(CCC)CCN.Cc1ccc2c(c1)nc(Cl)n[n+]2[O-]>>CCCN(CCC)CCNc1nc2cc(C)ccc2[n+]([O-])n1 -US07998975B2,3,C=CCC(=O)O.CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3nccc(CCc4ccc(Br)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C>>CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3nccc(CCc4ccc(/C=C/CC(=O)O)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C -US06093731,1,CC(C)(C)OC(=O)[C@@H]1CC[C@H](NS(=O)(=O)c2ccc3c(Cl)cnc(Cl)c3c2)CC1.N=C(N)N>>CC(C)(C)OC(=O)[C@@H]1CC[C@H](NS(=O)(=O)c2ccc3c(Cl)cnc(NC(=N)N)c3c2)CC1 -US04198422,7,CC(C)CSc1ccc2cc([N+](=O)[O-])c(N)cc2c1>>CC(C)CSc1ccc2cc(N)c(N)cc2c1 -US05653914,3,COc1ccc(OC)c(CP(=O)(OC)OC)c1.O=Cc1ccc(OCCCCCCO)cc1>>COc1ccc(OC)c(C=Cc2ccc(OCCCCCCO)cc2)c1 -US20150072974A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCCOc1cccc(Cl)n1>>Cc1ccc(S(=O)(=O)OCCCCOc2cccc(Cl)n2)cc1 -US20030187023A1,1,CCOC(CBr)OCC.Oc1ccc(Cl)cc1>>CCOC(COc1ccc(Cl)cc1)OCC -US04411903,1,CCCCCCCCCCC(=O)CCCCCBr.CCOC(=O)c1ccc(N)cc1>>CCCCCCCCCCC(=O)CCCCCNc1ccc(C(=O)OCC)cc1 -US20100029626A1,2,Nc1ccc(OCc2ccccc2)cc1O.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1ccc(OCc2ccccc2)cc1O -US20090239864A1,2,CC(=O)Cl.C[C@H](c1ccccc1)N1CCO[C@@H](c2ccc(N)cc2)C1>>CC(=O)Nc1ccc([C@H]2CN([C@H](C)c3ccccc3)CCO2)cc1 -US20120295897A1,1,O=C1Nc2c(Br)cccc2C1(CO)c1cc2c(cc1O)OCO2>>O=C1Nc2c(Br)cccc2C12COc1cc3c(cc12)OCO3 -US20070275954A1,2,CC(C)(C)OC(=O)NC(C(=O)O)c1cccs1.Nc1ncccc1C(=O)c1ccc(F)cc1>>CC(C)(C)OC(=O)NC(C(=O)Nc1ncccc1C(=O)c1ccc(F)cc1)c1cccs1 -US20140243374A1,2,CC1CCCC(N(Cc2ccc(C(=O)O)cc2)S(=O)(=O)c2ccc(Cl)cc2)C1.C[C@@H](N)CO>>CC1CCCC(N(Cc2ccc(C(=O)N[C@H](C)CO)cc2)S(=O)(=O)c2ccc(Cl)cc2)C1 -US06583135B2,1,BrCCOc1ccccc1.CC(C)(C)OC(=O)N1CCc2[nH]c3ccc(Cl)c(Cl)c3c2CC1>>CC(C)(C)OC(=O)N1CCc2c(n(CCOc3ccccc3)c3ccc(Cl)c(Cl)c23)CC1 -US20100256048A1,1,CO.N#Cc1ccc(OCCCCCCBr)cc1>>COCCCCCCOc1ccc(C#N)cc1 -US07704994B2,1,Ic1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1.O=C1CCCN1>>O=C1CCCN1c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1 -US20100004292A1,1,CC(C)(C)[Si](C)(C)OCCNc1ccc(NC(=O)c2ccccc2NC(=O)c2ccc(Cl)s2)cc1.N#CBr>>CC(C)(C)[Si](C)(C)OCCN(C#N)c1ccc(NC(=O)c2ccccc2NC(=O)c2ccc(Cl)s2)cc1 -US20100197908A1,7,O=Cc1ccc(C#Cc2ccc(OCc3ccccc3)nn2)cc1>>O=Cc1ccc(CCc2ccc(OCc3ccccc3)nn2)cc1 -US20070249630A1,6,Cc1cc(CCCCOCCCCCCN(Cc2ccccc2)C[C@H](O)c2ccc(O)c(CO)c2)cc(NC(N)=O)c1>>Cc1cc(CCCCOCCCCCCNC[C@H](O)c2ccc(O)c(CO)c2)cc(NC(N)=O)c1 -US20120322827A1,2,NCCc1coc(-c2ccc(F)cc2)n1.O=C(O)CCCc1noc(C(F)(F)F)n1>>O=C(CCCc1noc(C(F)(F)F)n1)NCCc1coc(-c2ccc(F)cc2)n1 -US20100056636A1,2,CC1CCC(C(C)C)C(C(=O)Cl)C1.NCCc1ccccc1>>CC1CCC(C(C)C)C(C(=O)NCCc2ccccc2)C1 -US07227023B2,1,BrCc1ccccc1.C=CCc1c(O)ccc2ncccc12>>C=CCc1c(OCc2ccccc2)ccc2ncccc12 -US20070123512A1,4,C=C(C)C(=O)Nc1ccc([N+](=O)[O-])c(C)c1.O=C(OO)c1cccc(Cl)c1>>Cc1cc(NC(=O)C2(C)CO2)ccc1[N+](=O)[O-] -US20140225069A1,7,O=[N+]([O-])c1cccc(-c2ccccc2)c1Nc1ccccc1>>Nc1cccc(-c2ccccc2)c1Nc1ccccc1 -US20080200460A1,2,CC(C)(C)OC(=O)N1CCC[C@H]1CC(=O)O.CCNC1CCN(CC[C@@H](c2cc(F)cc(F)c2)C2CCN(S(C)(=O)=O)CC2)CC1>>CCN(C(=O)C[C@@H]1CCCN1C(=O)OC(C)(C)C)C1CCN(CC[C@@H](c2cc(F)cc(F)c2)C2CCN(S(C)(=O)=O)CC2)CC1 -US20030018194A1,3,CC1(C2(C=O)CC2)OCCO1.CCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCC/C=C\C1(C2(C)OCCO2)CC1 -US20090270456A1,3,COC(=O)c1sc(Cl)nc1Cl.COc1ccc(B(O)O)cc1>>COC(=O)c1sc(-c2ccc(OC)cc2)nc1Cl -US04604389,1,CNCCCN1CCc2cc(OC)c(OC)cc2CC1=O.COc1ccc(SCCCCl)cc1OC>>COc1ccc(SCCCN(C)CCCN2CCc3cc(OC)c(OC)cc3CC2=O)cc1OC -US04460596,2,NCC(=O)c1ccsc1.O=C(Cl)c1ccc(F)cc1>>O=C(CNC(=O)c1ccc(F)cc1)c1ccsc1 -US20110237584A1,8,Cc1cncc(CO)c1>>Cc1cncc(C=O)c1 -US08895050B2,2,CCCCC/C=C/C(=O)O.COC(=O)[C@H](N)CC(C)C>>CCCCC/C=C/C(=O)N[C@H](CC(C)C)C(=O)OC -US07514460B2,2,COc1cc2ncnc(Nc3nc4ccc(N)cc4s3)c2cc1OC.O=C=Nc1cccc(C(F)(F)F)c1>>COc1cc2ncnc(Nc3nc4ccc(NC(=O)Nc5cccc(C(F)(F)F)c5)cc4s3)c2cc1OC -US09073929B2,3,Clc1c(Br)cncc1Br.OB(O)C1CC1>>Clc1c(Br)cncc1C1CC1 -US08063212B2,1,CN(Cc1cnc(F)cc1-c1cccc2cc(-c3nc(Cl)ncc3F)sc12)C(=O)OC(C)(C)C.NCCn1cc[nH]c1=O>>CN(Cc1cnc(F)cc1-c1cccc2cc(-c3nc(NCCn4cc[nH]c4=O)ncc3F)sc12)C(=O)OC(C)(C)C -US20080153850A1,1,COC(=O)CO.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(-c2cccnc2Cl)ccc1Cl>>COC(=O)COc1ncccc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 -US20140303172A1,1,Clc1nc2ccccc2nc1Cl.NS(=O)(=O)c1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)c1 -US20090163488A1,6,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)cc1NC(=O)OC(C)(C)C>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)cc1N -US20110294780A1,1,CCI.O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1C1CCNCC1>>CCN1CCC(N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)CC1 -US09067897B2,2,N#Cc1c(F)cccc1OCC1CCNCC1.O=C(Cl)c1cccc(Cl)c1>>N#Cc1c(F)cccc1OCC1CCN(C(=O)c2cccc(Cl)c2)CC1 -US05444083,2,CC(=O)Cl.COc1ccc([C@@H]2CNC[C@H]2Cc2cc(F)cc(F)c2OC)cc1OC>>COc1ccc([C@@H]2CN(C(C)=O)C[C@H]2Cc2cc(F)cc(F)c2OC)cc1OC -US07625932B2,7,CCOC(=O)c1c(-c2ccc(-c3ccccc3C=O)cc2)c(C#N)cn1C>>CCOC(=O)c1c(-c2ccc(-c3ccccc3CO)cc2)c(C#N)cn1C -US20060155121A1,3,Cc1cc(C)c(NC(=O)Cc2ccc(F)cc2)c(Br)c1.Nc1cccc(B(O)O)c1>>Cc1cc(C)c(NC(=O)Cc2ccc(F)cc2)c(-c2cccc(N)c2)c1 -US07482342B2,7,Cc1c(Br)cncc1[N+](=O)[O-]>>Cc1c(N)cncc1Br -US20150239844A1,3,CC(C)(C)Oc1cc(Br)c2cc(C(O)(c3ccc(Cl)cc3)c3nccs3)ccc2n1.CC1(C)OB(Cc2ccc(OC(F)(F)F)cc2)OC1(C)C>>CC(C)(C)Oc1cc(Cc2ccc(OC(F)(F)F)cc2)c2cc(C(O)(c3ccc(Cl)cc3)c3nccs3)ccc2n1 -US06858614B2,7,COc1ccc(C#CCCCO)cc1>>COc1ccc(CCCCCO)cc1 -US20150111870A1,2,CNOC.N#Cc1ccc(C(=O)O)cc1>>CON(C)C(=O)c1ccc(C#N)cc1 -US20080113966A1,6,O=C(OCc1ccccc1)N1CCC(c2cc(-c3ccccc3)n[nH]c2=O)CC1>>O=c1[nH]nc(-c2ccccc2)cc1C1CCNCC1 -US20100298299A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CCN2CCCC2)CC1>>N[C@@H]1CC[C@@H](CCN2CCCC2)CC1 -US04257952,6,CCOC(=O)Cn1c2c(c3ccccc31)CC(N(C)C)CC2>>CN(C)C1CCc2c(c3ccccc3n2CC(=O)O)C1 -US20100256097A1,1,CC(C)(O)c1ccc(-c2cc(C(N)=O)c(N)s2)c(F)c1.N#CC(CCO)c1cccc(Br)n1>>CC(C)(O)c1ccc(-c2cc(C(N)=O)c(Nc3cccc(C(C#N)CCO)n3)s2)c(F)c1 -US20090124624A1,1,COc1ccc2c(C(F)(F)F)nnc(Cl)c2c1.NC1CCN(Cc2ccccc2)CC1>>COc1ccc2c(C(F)(F)F)nnc(NC3CCN(Cc4ccccc4)CC3)c2c1 -US20060270637A1,2,COCC(=O)O.O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NO[C@H](CO)C3)nc2)c(F)c1>>COCC(=O)OC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1 -US20090023740A1,4,NC(=S)Nc1ccc(S(=O)(=O)Nc2nccs2)cn1.O=C(CBr)Cc1ccc(Cl)cc1>>O=S(=O)(Nc1nccs1)c1ccc(Nc2nc(Cc3ccc(Cl)cc3)cs2)nc1 -US20050165048A1,1,Cn1cc(CO)nn1.Oc1cc(Br)ccc1F>>Cn1cc(COc2cc(Br)ccc2F)nn1 -US05661153,7,Cn1c(=O)c(N=O)c(N)n(-c2ccccc2)c1=O>>Cn1c(=O)c(N)c(N)n(-c2ccccc2)c1=O -US20080249137A1,6,CCOc1cc(CC(=O)OC)cc(S(=O)(=O)c2cc(-c3ccc(C(F)(F)F)cc3)c(C)s2)c1>>CCOc1cc(CC(=O)O)cc(S(=O)(=O)c2cc(-c3ccc(C(F)(F)F)cc3)c(C)s2)c1 -US20110306587A1,1,Clc1cc(Cl)c(Cl)nn1.OCC1CCNCC1>>OCC1CCN(c2cc(Cl)nnc2Cl)CC1 -US06432950B1,1,FC(F)(F)c1cc2c(Cl)nc(-c3ccccn3)nc2s1.NCCc1ccc2c(c1)OCO2>>FC(F)(F)c1cc2c(NCCc3ccc4c(c3)OCO4)nc(-c3ccccn3)nc2s1 -US20050096380A1,1,CC(=O)c1cc2c(cc1O)OC(C)(C)C=C2C(C)C.CCCI>>CCCOc1cc2c(cc1C(C)=O)C(C(C)C)=CC(C)(C)O2 -US08022062B2,7,CC(C)(C)S(=O)(=O)Cc1ccc(C#N)cc1>>CC(C)(C)S(=O)(=O)Cc1ccc(CN)cc1 -US06867185B2,7,COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)O)C[C@H]5C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N4C3)cc(-c3ccccc3)nc2c1>>COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)O)C[C@H]5CCCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N4C3)cc(-c3ccccc3)nc2c1 -US05026856,6,CCNc1ccc2c(c1)CN(Cc1ccccc1)C2>>CCNc1ccc2c(c1)CNC2 -US20120207729A1,1,CC(C)(C)OC(=O)Nc1nc2c(-c3cccc([N+](=O)[O-])c3)cc(CBr)cc2s1.c1c[nH]cn1>>CC(C)(C)OC(=O)Nc1nc2c(-c3cccc([N+](=O)[O-])c3)cc(Cn3ccnc3)cc2s1 -US20110065669A1,3,Brc1ccc(OC[C@@H]2Cn3c(nc4ccccc43)O2)cc1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>Cn1nccc1-c1ccc(OC[C@@H]2Cn3c(nc4ccccc43)O2)cc1 -US20120289474A1,6,CCc1ccc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)s1>>CCc1ccc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)s1 -US20090149504A1,6,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccc(Oc3ccc(N)cc3)cc12)C(=O)N1CCC[C@H]1C#N>>N#CC1CCCN1C(=O)C(N)Cc1c[nH]c2ccc(Oc3ccc(N)cc3)cc12 -US20030114671A1,1,CCC(O)CC.Cc1cc(C)c(-c2cccc3c(Cl)cc(C)nc23)c(C)c1>>CCC(CC)Oc1cc(C)nc2c(-c3c(C)cc(C)cc3C)cccc12 -US20130064770A1,6,COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3[nH]2)CC1>>O=C(NCCCCN1CCN(c2ccccc2O)CC1)c1cc2ccccc2[nH]1 -US08299077B2,1,COC(=O)C(C)(C)c1ccc(N)nc1.Cn1cc(Br)cc(Br)c1=O>>COC(=O)C(C)(C)c1ccc(Nc2cc(Br)cn(C)c2=O)nc1 -US20150210666A1,8,OCCCCCCCCC1(CCCCc2ccccc2)OCCO1>>O=CCCCCCCCC1(CCCCc2ccccc2)OCCO1 -US05610192,1,NNC(=O)c1cc2ccccc2cc1O.O=Cc1cccc2ccccc12>>O=C(NN=Cc1cccc2ccccc12)c1cc2ccccc2cc1O -US05399578,10,Cc1ccc(-c2ccccc2C(=O)OCC[Si](C)(C)C)cc1.O=C1CCC(=O)N1Br>>C[Si](C)(C)CCOC(=O)c1ccccc1-c1ccc(CBr)cc1 -US20100003250A1,2,CCN1CCNCC1.CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)O)cc4)cc3)nc21>>CCN1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(-c4nc(N5CCOCC5)c5ccn(CC)c5n4)cc3)cc2)CC1 -US07045528B2,3,C[Sn](C)(C)c1cc2nccc(Cl)c2s1.O=Cc1cccc(Br)n1>>O=Cc1cccc(-c2cc3nccc(Cl)c3s2)n1 -US04511569,1,CN.O=c1[nH]c2c(cc1Cl)-c1ccccc1CC2>>CNc1cc2c([nH]c1=O)CCc1ccccc1-2 -US03996230,1,CN1CCNCC1.Cc1cc(Br)cc2c1-n1c(Br)nnc1CN=C2c1ccccn1>>Cc1cc(Br)cc2c1-n1c(nnc1N1CCN(C)CC1)CN=C2c1ccccn1 -US20100113780A1,1,CCOc1nc(C)cc(=O)[nH]1.N#Cc1ccccc1-c1ccc(CBr)cc1>>CCOc1nc(C)cc(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US07414060B2,1,Brc1cccnc1.Cc1ccc(N)c(C(=O)Nc2ccc(F)cn2)n1>>Cc1ccc(Nc2cccnc2)c(C(=O)Nc2ccc(F)cn2)n1 -US05250548,7,CCCCc1ncc(C#N)c(NCc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)n1>>CCCCc1ncc(CN)c(NCc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)n1 -US20090137548A1,6,COC(=O)c1ccc(-c2ccc(Cl)c(-c3ccc(C(F)(F)F)cc3CN3C(=O)O[C@H](c4cc(C(F)(F)F)cc(C(F)(F)F)c4)[C@@H]3C)c2)c(C)c1>>Cc1cc(C(=O)O)ccc1-c1ccc(Cl)c(-c2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)c1 -US20090137580A1,7,Nc1ccc(C(=O)N2CCOCC2)c(C(F)(F)F)c1>>Nc1ccc(CN2CCOCC2)c(C(F)(F)F)c1 -US08895752B2,2,CC(=O)Oc1ccccc1C(=O)O.Nc1nccs1>>CC(=O)Oc1ccccc1C(=O)Nc1nccs1 -US20100041892A1,6,CCOC(=O)/C=C/c1ccc(OCCCS(C)(=O)=O)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CS(=O)(=O)CCCOc1ccc(/C=C/C(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1 -US20060100431A1,7,COC(=O)C[C@@H]1C=CCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=C[C@H]1CCO -US04992432,2,CC(=O)Cl.COc1ccc(-c2ccccc2C(SCC(=O)c2ccccc2)C(O)C(N)=O)cc1>>COc1ccc(-c2ccccc2C(SCC(=O)c2ccccc2)C(OC(C)=O)C(N)=O)cc1 -US08293768B2,2,Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)O.NCc1cc(F)cc(F)c1>>Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1cc(F)cc(F)c1 -US20120040951A1,9,Cn1cnc2cnc(Br)cc21.[C-]#N>>Cn1cnc2cnc(C#N)cc21 -US20080058383A1,1,CC(C)(N)CO.Cc1nc(Cl)ccc1[N+](=O)[O-]>>Cc1nc(NC(C)(C)CO)ccc1[N+](=O)[O-] -US07368578B2,3,CCC[Mg+].COc1cc(COc2nn(-c3ccccc3)cc2/C=C/C(=O)N(C)OC)ccc1OCc1nc(-c2ccco2)oc1C>>CCCC(=O)/C=C/c1cn(-c2ccccc2)nc1OCc1ccc(OCc2nc(-c3ccco3)oc2C)c(OC)c1 -US20050234101A1,1,CC1CCN(CCCl)CC1.Oc1ccc(I)cc1>>CC1CCN(CCOc2ccc(I)cc2)CC1 -US20120245344A1,1,Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)cnc1CO.c1ncn(-c2ccc3[nH]ccc3c2)n1>>Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)cnc1Cn1ccc2cc(-n3cncn3)ccc21 -US06034272,8,CC(=O)N(CCCC(O)c1ccccc1)C(C)C>>CC(=O)N(CCCC(=O)c1ccccc1)C(C)C -US04348399,6,CCCCCCCCCCCCCCCCNc1ccc(CC(=O)OCC)cc1>>CCCCCCCCCCCCCCCCNc1ccc(CC(=O)O)cc1 -US20120129855A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=C(CCl)N1CCCC1>>CC(C)(C)OC(=O)N1CCC(OCC(=O)N2CCCC2)CC1 -US20110144056A1,3,CC(C)(O)c1ccc(Br)cn1.CCCC[Sn](CCCC)(CCCC)c1ccn(-c2ccc(F)cc2)n1>>CC(C)(O)c1ccc(-c2ccn(-c3ccc(F)cc3)n2)cn1 -US20040209933A1,1,ClCc1coc(C=Cc2ccc3c(c2)OCO3)n1.Oc1ccc(CCCCn2ccnn2)cc1>>C(=Cc1nc(COc2ccc(CCCCn3ccnn3)cc2)co1)c1ccc2c(c1)OCO2 -US08129376B2,2,Cc1cccc(OC2CCNCC2)c1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>Cc1cccc(OC2CCN(C(=O)CNC(=O)c3cc(-c4ccccc4)[nH]n3)CC2)c1 -US20140323468A1,3,CC(O)c1ccncc1Br.CC1(C)OB(c2cnc3c(c2)CCCN3)OC1(C)C>>CC(O)c1ccncc1-c1cnc2c(c1)CCCN2 -US20110281845A1,1,O=C(CI)NCCc1ccccc1.O=C(Nc1ccc(-c2ccccc2Cl)[nH]c1=O)OCc1ccccc1>>O=C(Cn1c(-c2ccccc2Cl)ccc(NC(=O)OCc2ccccc2)c1=O)NCCc1ccccc1 -US03991076,4,CN(C)CCCN.O=C(CC1CSCCC1=O)c1ccccc1>>CN(C)CCCn1c(-c2ccccc2)cc2c1CCSC2 -US20080167307A1,6,COC(=O)c1cc(-c2ccc(F)cc2)ccc1OCCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1>>CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(-c3ccc(F)cc3)cc2C(=O)O)cs1 -US08329687B2,1,CC(C)(C)OC(=O)N1CCOc2nc(Cl)ccc2C1.CC(O)C1CCCCC1>>CC(Oc1ccc2c(n1)OCCN(C(=O)OC(C)(C)C)C2)C1CCCCC1 -US20150152117A1,9,COc1ccc(Cl)cc1-c1nc(Br)sc1NC(=O)c1cnn2cccnc12>>COc1ccc(Cl)cc1-c1ncsc1NC(=O)c1cnn2cccnc12 -US20110263584A1,3,CCOc1ncc(Br)cc1C.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>CCOc1ncc(-c2ccc([C@H](C)N3CC[C@](CC(C)(C)O)(c4ccccc4)OC3=O)cc2)cc1C -US06353111B1,2,CS(=O)(=O)c1ccc(/C(=C\C2CCCCC2)C(=O)O)cc1C(F)(F)F.Nc1ccc(Br)cn1>>CS(=O)(=O)c1ccc(/C(=C\C2CCCCC2)C(=O)Nc2ccc(Br)cn2)cc1C(F)(F)F -US20130303538A1,2,COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1.O=C(O)c1ccncc1>>COC(=O)N1CC[C@@H]2[C@H]1CCC[C@]2(C#Cc1cccc(C)c1)OC(=O)c1ccncc1 -US20070293444A1,2,CC(=O)N1CCc2ccc(N)cc2C1.O=C(O)C(F)(F)F>>CC(=O)N1CCc2ccc(NC(=O)C(F)(F)F)cc2C1 -US20150239884A1,6,COC(=O)c1nc(SC)ncc1C#CC1CC1>>CSc1ncc(C#CC2CC2)c(C(=O)O)n1 -US20070208066A1,2,COc1ccc(C(=O)Cl)cc1.Nc1ccc(O)cc1Cl>>COc1ccc(C(=O)Nc2ccc(O)cc2Cl)cc1 -US05866572,3,CC(C)OB(OC(C)C)c1cccs1.Fc1ccc(Nc2ncnc3ccc(Br)cc23)cc1Cl>>Fc1ccc(Nc2ncnc3ccc(-c4cccs4)cc23)cc1Cl -US08202856B2,1,NC1CCC(C(=O)O)CC1.O=Cc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1>>O=C(O)[C@@H]1CC[C@@H](NCc2ccc(-c3noc(-c4nnn(-c5ccccc5F)c4-c4ccncc4)n3)cc2)CC1 -US05578627,1,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.COCC(N)COc1noc2ccc(Cl)cc12>>COCC(COc1noc2ccc(Cl)cc12)NCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 -US04578381,2,CC(=O)OC(C)=O.O=C1Nc2ccccc2C1=O>>CC(=O)N1C(=O)C(=O)c2ccccc21 -US07625908B2,1,CC(=O)NC[C@@H](C)Oc1cccc2ncnc(Nc3ccc(O)c(C)c3)c12.Fc1cccc(CCl)c1>>CC(=O)NC[C@@H](C)Oc1cccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(C)c3)c12 -US07678815B2,1,Brc1cccnc1.CCOC(=O)c1nc(CCOC)sc1N>>CCOC(=O)c1nc(CCOC)sc1Nc1cccnc1 -US07504408B2,1,COC(C)C#Cc1cc(Cl)c(N)c2c1OCO2.COc1cc2c(Cl)ncnc2cc1OCCCN1CCOCC1>>COc1cc2c(Nc3c(Cl)cc(C#CC(C)OC)c4c3OCO4)ncnc2cc1OCCCN1CCOCC1 -US20110257151A1,1,CCOC(=O)c1ccc(N)cc1.O=Cc1ccc(F)c(Br)c1>>CCOC(=O)c1ccc(N=Cc2ccc(F)c(Br)c2)cc1 -US20080167307A1,1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCO)cs1.O=[N+]([O-])c1ccc(-c2ccc(O)cc2)cc1>>CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(-c3ccc([N+](=O)[O-])cc3)cc2)cs1 -US08101764B2,1,COC(=O)c1ccc(Br)cn1.O=C1NCCc2cc(-c3ccc(Cl)cc3)sc21>>COC(=O)c1ccc(N2CCc3cc(-c4ccc(Cl)cc4)sc3C2=O)cn1 -US20060211697A1,6,COc1cc(C)ccc1Oc1ccc([N+](=O)[O-])cc1>>Cc1ccc(Oc2ccc([N+](=O)[O-])cc2)c(O)c1 -US20040176405A1,6,CC(C)(C)OC(=O)NC1CCCC(CNC(=O)OCc2ccccc2)C1>>NC1CCCC(CNC(=O)OCc2ccccc2)C1 -US04772600,2,NC(=O)CNc1ncccc1N.O=C(O)c1ccccn1>>NC(=O)CNc1ncccc1NC(=O)c1ccccn1 -US20100222321A1,9,Clc1nccc2nc(-c3ccc(CN4CCC(c5nnc(-c6ncccn6)[nH]5)CC4)cc3)c(-c3ccccc3)cc12.NN>>NNc1nccc2nc(-c3ccc(CN4CCC(c5nnc(-c6ncccn6)[nH]5)CC4)cc3)c(-c3ccccc3)cc12 -US05393875,9,CC(C)(C(=O)Cl)S(=O)(=O)CC(Cc1ccccc1)C(=O)OCc1ccccc1.N>>CC(C)(C(N)=O)S(=O)(=O)CC(Cc1ccccc1)C(=O)OCc1ccccc1 -US08440710B2,6,O=C1N(c2ccc3c(c2)OC(F)(F)O3)CCC12CCC1(CC2)OCCO1>>O=C1CCC2(CC1)CCN(c1ccc3c(c1)OC(F)(F)O3)C2=O -US06727248B2,3,C#CCn1cncc1C.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)cc(I)c21>>Cc1cncn1CC#Cc1cc(CN2CCOCC2)cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12 -US08338605B2,1,Cc1ccc2c(Cl)ccnc2n1.Nc1cc(COc2ccc(Br)cc2)ccc1Sc1ccc(O)cc1>>Cc1ccc2c(Nc3cc(COc4ccc(Br)cc4)ccc3Sc3ccc(O)cc3)ccnc2n1 -US20120022109A1,1,N#Cc1cccc(CBr)c1.NCCO>>N#Cc1cccc(CNCCO)c1 -US07572934B2,1,COc1ccc(F)c(-c2cc(CCl)ccc2C2CC2)c1.O=C(O)CCc1cccc(O)c1>>COc1ccc(F)c(-c2cc(COc3cccc(CCC(=O)O)c3)ccc2C2CC2)c1 -US07030119B1,1,COC(=O)c1cc([N+](=O)[O-])c(OC(=S)N(C)C)c(F)c1F.Cc1ccccc1N>>COC(=O)c1cc([N+](=O)[O-])c(OC(=S)N(C)C)c(F)c1Nc1ccccc1C -US20150166513A1,1,C[C@@H](CO)NC(=O)Cn1cc(N)cn1.Clc1nccc(NCc2c(Cl)cccc2Cl)n1>>C[C@@H](CO)NC(=O)Cn1cc(Nc2nccc(NCc3c(Cl)cccc3Cl)n2)cn1 -US20100272680A1,6,COC(=O)c1nc2c(C(F)(F)F)cc(-c3cccn3C(=O)OC(C)(C)C)cn2c1Cl>>CC(C)(C)OC(=O)n1cccc1-c1cc(C(F)(F)F)c2nc(C(=O)O)c(Cl)n2c1 -US08017611B2,3,CC(C)(C)OC(=O)N1CCC(n2cc(Br)c(C=O)n2)CC1.CC1(C)OB(c2cnc(N)c(-c3nc4ccccc4o3)c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc(N)c(-c4nc5ccccc5o4)c3)c(C=O)n2)CC1 -US20150166549A1,1,CC(N)c1oc(=O)c2ccccc2c1-c1cn[nH]c1.Clc1ncnc2ccsc12>>CC(Nc1ncnc2ccsc12)c1oc(=O)c2ccccc2c1-c1cn[nH]c1 -US20130281438A1,6,COC(=O)c1cc2cccc([N+](=O)[O-])c2o1>>O=C(O)c1cc2cccc([N+](=O)[O-])c2o1 -US20050288346A1,1,CCCc1c(O)ccc(C(C)=O)c1O.COC(=O)c1ccc(OCCCCBr)cc1>>CCCc1c(OCCCCOc2ccc(C(=O)OC)cc2)ccc(C(C)=O)c1O -US07846949B2,1,CC(C)(C)OC(=O)CBr.O=C(Nc1cccc(Br)c1)c1c(F)cccc1F>>CC(C)(C)OC(=O)CN(C(=O)c1c(F)cccc1F)c1cccc(Br)c1 -US20060020003A1,6,CCCCc1oc2ccccc2c1C(=O)N(C)Cc1ccc(-c2ccc(OCC(=O)OC)c(Br)c2)cc1>>CCCCc1oc2ccccc2c1C(=O)N(C)Cc1ccc(-c2ccc(OCC(=O)O)c(Br)c2)cc1 -US08754215B2,2,NCCc1ccccc1.O=C(Cl)CCl>>O=C(CCl)NCCc1ccccc1 -US20050014812A1,1,Cc1cc(CO)cc2c1nc(C)n2Cc1ccc(-c2ccccc2)cc1Cl.O=C(O)c1ccnc(Cl)c1>>Cc1cc(COc2cc(C(=O)O)ccn2)cc2c1nc(C)n2Cc1ccc(-c2ccccc2)cc1Cl -US04214081,7,COc1cccc(C=NCCc2ccccc2)c1OCCCN1CCOCC1>>COc1cccc(CNCCc2ccccc2)c1OCCCN1CCOCC1 -US20120184542A1,2,COC(=O)CC(=O)Cl.C[C@@H](NC(=O)c1ccc(Cl)c(N)c1)c1ccccc1>>COC(=O)CC(=O)Nc1cc(C(=O)N[C@H](C)c2ccccc2)ccc1Cl -US20130090323A1,1,COc1cncc(-c2cnc(N3CCOCC3)cc2N)c1.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Cl>>COc1cncc(-c2cnc(N3CCOCC3)cc2Nc2c(C)c(-c3ccccn3)nc3cc(F)cc(F)c23)c1 -US20080071084A1,1,CCO.Cc1ccsc1Br>>CCOc1sccc1C -US08889702B2,7,CC(C)(C)OC(=O)N1CCC2(CC(C#N)C2)C1>>CC(C)(C)OC(=O)N1CCC2(CC(CN)C2)C1 -US20090156642A1,9,CN(Cc1cc(S(=O)(=O)c2ccc(Cl)nc2)n(-c2ccccc2F)n1)C(=O)OC(C)(C)C>>CN(Cc1cc(S(=O)(=O)c2cccnc2)n(-c2ccccc2F)n1)C(=O)OC(C)(C)C -US20100022515A1,2,CC(C)OC(=O)N1CCC(CCCO)CC1.CS(=O)(=O)Cl>>CC(C)OC(=O)N1CCC(CCCOS(C)(=O)=O)CC1 -US20080132459A1,3,CC(=O)c1ccc(Br)cc1.COc1ccc(C(=O)Nc2cc(B3OC(C)(C)C(C)(C)O3)ccc2N)cc1>>COc1ccc(C(=O)Nc2cc(-c3ccc(C(C)=O)cc3)ccc2N)cc1 -US20090247567A1,1,CC(=O)N1CCNCC1.CN(C(=O)c1cc2c(s1)-c1cc(Br)ccc1OC2)c1ccc(F)cc1F>>CC(=O)N1CCN(c2ccc3c(c2)-c2sc(C(=O)N(C)c4ccc(F)cc4F)cc2CO3)CC1 -US04096147,3,COc1cc2c(cc1OC)C1CC(=O)C3CCCCC3N1CC2.[Mg+]c1ccccc1>>COc1cc2c(cc1OC)C1CC(O)(c3ccccc3)C3CCCCC3N1CC2 -US05183587,9,CCC[C@@H]1CC[C@@H]([C@H]2CC[C@H](C=C(F)F)CC2)CC1>>CCC[C@@H]1CC[C@@H]([C@H]2CC[C@H](/C=C/F)CC2)CC1 -US06531599B2,6,CCOC(=O)c1ccc(C#Cc2cc(C3CC3)c3c(c2)C(C)(C)CC(C)(C)O3)cc1>>CC1(C)CC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)cc(C3CC3)c2O1 -US20100179111A1,1,CN.Oc1ccc(CCBr)cc1>>CNCCc1ccc(O)cc1 -US06303793B1,3,C#CC(O)CC.O=C1Nc2ccc(F)c(I)c2/C1=C/c1ccc[nH]1>>CCC(O)C#Cc1c(F)ccc2c1/C(=C/c1ccc[nH]1)C(=O)N2 -US20060047171A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(CC(=O)O)ccc1OCCN>>COc1cc(CC(=O)O)ccc1OCCNC(=O)OC(C)(C)C -US20060178400A1,1,CCCCCc1ccc(O)cc1.Fc1ccc(Br)cn1>>CCCCCc1ccc(Oc2ccc(Br)cn2)cc1 -US20070265303A1,6,CC(C)N(CC[C@H](c1ccccc1)c1cc(OCCCCCCCNC[C@H](O[Si](C)(C)C(C)(C)C)c2ccc(O)c(NS(C)(=O)=O)c2)ccc1O)C(C)C>>CC(C)N(CC[C@H](c1ccccc1)c1cc(OCCCCCCCNC[C@H](O)c2ccc(O)c(NS(C)(=O)=O)c2)ccc1O)C(C)C -US20150166549A1,6,CC(c1oc(=O)c2ccccc2c1-c1cncs1)n1nc(-c2cc(F)cc(O[Si](C)(C)C(C)(C)C)c2)c2c(N)ncnc21>>CC(c1oc(=O)c2ccccc2c1-c1cncs1)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21 -US05541324,2,Fc1cccc2c1NCc1c(-c3noc(C4CC4)n3)ncn1-2.O=C(Cl)c1ccccc1>>O=C(c1ccccc1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2cccc(F)c21 -US20050215556A1,1,C=CCBr.Cc1ccc(O)c([N+](=O)[O-])c1>>C=CCOc1ccc(C)cc1[N+](=O)[O-] -US08309542B2,2,CC(C)(C)OC(=O)N[C@@H]1CCNC1.CN1CCc2cc(C(=O)O)ccc2C1>>CN1CCc2cc(C(=O)N3CC[C@@H](NC(=O)OC(C)(C)C)C3)ccc2C1 -US20100093814A1,4,NC(N)=S.O=C1CCCC1Cl>>Nc1nc2c(s1)CCC2 -US20140171417A1,7,Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1cccc(F)c1F)=CCC3>>Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1cccc(F)c1F)CCC3 -US20140323518A1,9,COc1ccc(-c2cc(OC(F)(F)F)cc(Br)c2N)cc1.N#C[Cu]>>COc1ccc(-c2cc(OC(F)(F)F)cc(C#N)c2N)cc1 -US05190955,1,CCN1CCNCC1.N#Cc1c(Cl)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2C#N)CC1 -US08129376B2,2,NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1.O=C(O)c1cn(-c2ccccc2)cn1>>O=C(NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1)c1cn(-c2ccccc2)cn1 -US20140357858A1,2,CC(C)(Oc1ccccc1)C(=O)O.Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1>>CC(C)(Oc1ccccc1)C(=O)Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1 -US04550107,2,CCOC(=O)c1c(Nc2ccccc2N)c(Cl)cn1C>>Cn1cc(Cl)c2c1C(=O)Nc1ccccc1N2 -US04337201,1,CC(C)(C)C(=O)OCCl.O=C(O)[C@@H]1C[C@H](c2ccccc2)CN1C(=O)OCc1ccccc1>>CC(C)(C)C(=O)OCOC(=O)[C@@H]1C[C@H](c2ccccc2)CN1C(=O)OCc1ccccc1 -US06380400B1,1,CN(C)C(=S)Cl.Cc1cc(O)c(C(C)(C)C)cc1C=O>>Cc1cc(OC(=S)N(C)C)c(C(C)(C)C)cc1C=O -US07524846B2,6,CC#Cc1ccc(C(CN2CCN(C(=O)OC(C)(C)C)CC2)C2(O)CCCCC2)cc1>>CC#Cc1ccc(C(CN2CCNCC2)C2(O)CCCCC2)cc1 -US20050075327A1,2,CC(=O)OC(C)=O.CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CNc2ccccc21>>CC(=O)N1C[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)c2ccccc21 -US08263656B2,7,COc1cc(Cl)ccc1C#CCCO>>COc1cc(Cl)ccc1CCCCO -US08569522B2,2,COC(=O)C1CCOc2cc(Oc3ccc(C(=O)O)cc3)c(C#N)cc21.Cc1ccc(-c2cccc(N)c2)cc1C>>COC(=O)C1CCOc2cc(Oc3ccc(C(=O)Nc4cccc(-c5ccc(C)c(C)c5)c4)cc3)c(C#N)cc21 -US20100160308A1,9,CCOC(=O)c1sc(Cl)nc1-c1ccc(C(F)(F)F)cc1.[N-]=[N+]=[N-]>>CCOC(=O)c1sc(N=[N+]=[N-])nc1-c1ccc(C(F)(F)F)cc1 -US20060004003A1,8,CCn1ncc2c(-c3ccc(Cl)s3)c(CO)c(C(C)C)nc21>>CCn1ncc2c(-c3ccc(Cl)s3)c(C=O)c(C(C)C)nc21 -US08053581B2,4,NC(N)=S.O=C(c1ccc(F)cc1)C(Br)Cc1ccc([N+](=O)[O-])cc1>>Nc1nc(-c2ccc(F)cc2)c(Cc2ccc([N+](=O)[O-])cc2)s1 -US20150148533A1,6,COC(=O)CC(N)Cc1cc(F)c(F)cc1F>>NC(CC(=O)O)Cc1cc(F)c(F)cc1F -US07005440B1,10,COC(=O)c1c(C)cccc1C.O=C1CCC(=O)N1Br>>COC(=O)c1c(C)cccc1CBr -US07524860B2,3,CCNC(=O)Nc1nc2cc(Br)ccn2n1.OB(O)c1cccnc1>>CCNC(=O)Nc1nc2cc(-c3cccnc3)ccn2n1 -US07994423B2,2,CC(=O)Cl.Nc1ccc(F)c(F)c1>>CC(=O)Nc1ccc(F)c(F)c1 -US20140194418A1,9,CSc1cc(Nc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2S(C)=O)c(C(N)=O)c(Cl)n1.N>>CSc1cc(Nc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2S(C)=O)c(C(N)=O)c(N)n1 -US20080262229A1,6,CCN(CC)C(=O)c1ccc(C(c2ccc(NC(=O)OC)cc2)N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CCN(CC)C(=O)c1ccc(C(c2ccc(NC(=O)OC)cc2)N2CCNCC2)cc1 -US07737302B2,1,CC(Br)C(=O)c1cccc(Cl)c1.CC(C)(C)N>>CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 -US05451596,3,CCOC(=O)C1CC1C=O.c1ccc([P+](Cc2ccc(-c3nc4ccccc4o3)cc2)(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)[C@@H]1C[C@H]1/C=C/c1ccc(-c2nc3ccccc3o2)cc1 -US05451596,3,CCOC(=O)C1CC1C=O.c1ccc([P+](Cc2ccc(-c3nc4ccccc4o3)cc2)(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)[C@@H]1C[C@H]1/C=C\c1ccc(-c2nc3ccccc3o2)cc1 -US09056110B2,6,COC(=O)c1ccc(C)c(-n2c(C)nc(OCc3ccc(F)cc3F)c(Cl)c2=O)c1>>Cc1ccc(C(=O)O)cc1-n1c(C)nc(OCc2ccc(F)cc2F)c(Cl)c1=O -US20100331326A1,1,CC1CN(c2ccc3ncsc3c2)C(=O)N1.Cc1ccncc1I>>Cc1ccncc1N1C(=O)N(c2ccc3ncsc3c2)CC1C -US03996374,1,CC(C)(CCBr)CCBr.CCOC(=O)c1[nH]c(-c2ccccc2)c2cc(Cl)ccc12>>CCOC(=O)c1c2ccc(Cl)cc2c(-c2ccccc2)n1CCC(C)(C)CCBr -US07858781B2,6,CCOC(=O)c1cc2c(OCC3CCCC3)cccc2[nH]1>>O=C(O)c1cc2c(OCC3CCCC3)cccc2[nH]1 -US20080171748A1,3,C=C[Mg+].COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(=O)N(C)OC)C[C@@H]3c3ccc(OC)cc3)cc21>>C=CC(=O)C[C@H]1C[C@H](c2ccc(OC)cc2)[C@@H](OCc2ccc3c(c2)N(CCCOC)CCO3)CN1S(=O)(=O)c1ccc(C)cc1 -US07560558B2,1,C1COCCN1.COc1ccc(Oc2ccnc3cc(OCCCl)c(OC)cc23)c(C(C)=O)c1>>COc1ccc(Oc2ccnc3cc(OCCN4CCOCC4)c(OC)cc23)c(C(C)=O)c1 -US03943124,7,C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C(=O)OCCCN3CCOCC3)CC[C@@H]12>>C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C(=O)OCCCN3CCOCC3)CC[C@@H]12 -US20030096841A1,2,Nc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C1CCC(N2C(=O)c3cccc(NC(=O)c4ccc([N+](=O)[O-])cc4)c3C2=O)C(=O)N1 -US20080200448A1,2,CC(C)OC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCC1=O.NS(=O)(=O)Cc1ccc(F)cc1F>>CC(C)OC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccc(F)cc3F)CC2)nc1CN1CCCC1=O -US20060052315A1,1,CNCC(O)c1ccccc1.Cn1nc(-c2ccc(C=O)s2)cc1C(F)(F)F>>CN(Cc1ccc(-c2cc(C(F)(F)F)n(C)n2)s1)CC(O)c1ccccc1 -US20060100204A1,4,CCOC(=O)C(C=O)C=O.Cc1ccc(C(=O)O)cc1NN>>CCOC(=O)c1cnn(-c2cc(C(=O)O)ccc2C)c1 -US05935952,6,O=C(O)c1cn(C2CC2)c2c(CF)c(-c3ccc4c(c3)CN(C(=O)OCc3ccccc3)C4)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2c(CF)c(-c3ccc4c(c3)CNC4)c(F)cc2c1=O -US20040087568A1,1,CC(=O)c1ccnc(N)n1.CC(C)(C)OC(=O)N1Cc2cc(NC(=O)c3ccccc3N)ccc2C(C)(C)C1>>CC(Nc1ccccc1C(=O)Nc1ccc2c(c1)CN(C(=O)OC(C)(C)C)CC2(C)C)c1ccnc(N)n1 -US07968587B2,2,CC(C)OC(=O)Cl.N#Cc1ccc2c(c1)c1c(n2Cc2ccccn2)CC(N)C1>>CC(C)OC(=O)NC1Cc2c(n(Cc3ccccn3)c3ccc(C#N)cc23)C1 -US06849657B2,1,C=COCC.O=C1CC[C@H](CO)N1>>CCOC(C)OC[C@H]1CCC(=O)N1 -US08883788B2,1,Cn1c(CCCO)nc2ccccc21.Cn1cc(O)c(=O)c(-c2ccnn2-c2ccccc2)n1>>Cn1cc(OCCCc2nc3ccccc3n2C)c(=O)c(-c2ccnn2-c2ccccc2)n1 -US07514417B2,6,CCOC(=O)c1cnn(-c2nc(NC3CCCC3)c3ncn(C4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)c1>>O=C(O)c1cnn(-c2nc(NC3CCCC3)c3ncn(C4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)c1 -US20110190285A1,2,CO.O=C(O)c1ccc(Cl)cc1>>COC(=O)c1ccc(Cl)cc1 -US20140187533A1,2,CC(C)(C)OC(=O)N1CCN(CC(=O)O)C(=O)C1.Nc1ccc(C(F)(F)F)cn1>>CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2ccc(C(F)(F)F)cn2)C(=O)C1 -US09133224B2,3,CNC(=O)c1nc(B2OC(C)(C)C(C)(C)O2)ccc1N.N#Cc1nn(CCCO)cc1Br>>CNC(=O)c1nc(-c2cn(CCCO)nc2C#N)ccc1N -US07279580B2,3,CC(C)(O)c1ccn2c(-c3ccc(F)c(Cl)c3)cnc2c1F.COc1ccccc1B(O)O>>COc1ccccc1-c1cc(-c2cnc3c(F)c(C(C)(C)O)ccn23)ccc1F -US20120053180A1,1,CS(=O)(=O)OC1CCC(OCc2ccccc2)CC1.Oc1c(F)cc(Br)cc1F>>Fc1cc(Br)cc(F)c1OC1CCC(OCc2ccccc2)CC1 -US20040162311A1,7,Cn1cc(CNc2ccccc2[N+](=O)[O-])c2ccccc21>>Cn1cc(CNc2ccccc2N)c2ccccc21 -US04042596,3,Cc1nc(C(=O)Cl)c(CCc2ccccc2)o1>>Cc1nc2c(o1)CCc1ccccc1C2=O -US20130090323A1,7,CC1(C)CCC=C1c1cnc(N2CCOCC2)cc1N>>CC1(C)CCCC1c1cnc(N2CCOCC2)cc1N -US08975256B2,1,CI.COc1ccc(F)cc1-c1ccc2c(c1COC(=O)c1ccccc1)NC(=O)C(C)(C)N2>>COc1ccc(F)cc1-c1ccc2c(c1COC(=O)c1ccccc1)N(C)C(=O)C(C)(C)N2 -US20120259123A1,7,CCOC(=O)c1cccc(N(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1>>CC(C)(C)OC(=O)CN(C(=O)OC(C)(C)C)c1cccc(CO)n1 -US05084463,7,CN(Cc1ccc2cc([N+](=O)[O-])ccc2n1)CC(O)COc1ccc(NS(C)(=O)=O)cc1>>CN(Cc1ccc2cc(N)ccc2n1)CC(O)COc1ccc(NS(C)(=O)=O)cc1 -US20060217382A1,1,Cc1nc(-c2cccc(C(F)(F)F)c2)n2nc(N)ncc12.Oc1ccc(Br)cc1>>Cc1nc(-c2cccc(C(F)(F)F)c2)n2nc(Nc3ccc(O)cc3)ncc12 -US20100331326A1,1,C1COCCN1.O=Cc1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O>>O=C1N(c2ccc3ncsc3c2)CCN1c1cnccc1CN1CCOCC1 -US20070032515A1,1,COC(=O)c1cccc(OC(=O)c2ccccc2)c1O.COCCBr>>COCCOc1c(OC(=O)c2ccccc2)cccc1C(=O)OC -US05834482,1,CCc1noc(-c2cc3c(cn2)[nH]c2ccc(S(=O)(=O)N(C)C)cc23)n1.ClCCCBr>>CCc1noc(-c2cc3c4cc(S(=O)(=O)N(C)C)ccc4n(CCCCl)c3cn2)n1 -US20130287730A1,1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1.O=C1CCN(C(=O)OCc2ccccc2)CC1>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1C1CCN(C(=O)OCc2ccccc2)CC1 -US08748426B2,6,COC(=O)C1(N2Cc3ccc(-c4ccc(NC(=O)c5ccc(OC(F)(F)F)cc5)cc4)cc3C2=O)CCCC1>>O=C(Nc1ccc(-c2ccc3c(c2)C(=O)N(C2(C(=O)O)CCCC2)C3)cc1)c1ccc(OC(F)(F)F)cc1 -US07829726B2,1,Clc1cccc2c(CBr)csc12.OC(Cn1ccnc1)c1ccc(Cl)cc1Cl>>Clc1ccc(C(Cn2ccnc2)OCc2csc3c(Cl)cccc23)c(Cl)c1 -US08486950B2,9,[N-]=[N+]=Nc1cc(NC(=O)c2c(Cl)cc(Cl)cc2Cl)ccn1>>Nc1cc(NC(=O)c2c(Cl)cc(Cl)cc2Cl)ccn1 -US20140329862A1,3,COC(=O)c1ccc(C=O)nc1.C[Mg+]>>COC(=O)c1ccc(C(C)O)nc1 -US20150197510A1,7,COC(=O)[C@H]1CCC[C@H]1NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H]1CCC[C@@H]1CO -US20150141422A1,6,COC(=O)c1ccc2nc(-c3ccccc3)c(-c3cccc(C(=O)O)c3)nc2c1>>O=C(O)c1cccc(-c2nc3cc(C(=O)O)ccc3nc2-c2ccccc2)c1 -US04803215,9,NN.O=S(=O)(c1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1Br)C(F)(F)F>>NNc1c(S(=O)(=O)C(F)(F)F)cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl -US20020068734A1,2,CCN=C=S.COc1cc2ncnc(N3CCN(C(=O)Nc4ccc(N)cc4)CC3)c2cc1OC>>CCNC(=S)Nc1ccc(NC(=O)N2CCN(c3ncnc4cc(OC)c(OC)cc34)CC2)cc1 -US20110059957A1,6,C#Cc1csc(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>C#Cc1csc(C2CCNCC2)n1 -US06465507B2,3,CNS(=O)(=O)c1ccc2c(c1C)CC(=O)N2.O=Cc1[nH]cc2c1CCOC2=O>>CNS(=O)(=O)c1ccc2c(c1C)C(=Cc1[nH]cc3c1CCOC3=O)C(=O)N2 -US05455252,3,CC(C)c1ccc(N)c(Br)c1.O=[N+]([O-])c1cccc(B(O)O)c1>>CC(C)c1ccc(N)c(-c2cccc([N+](=O)[O-])c2)c1 -US20090036492A1,1,CCc1c(C)cc(C)c(C)c1C=O.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCc1c(C)cc(C)c(C)c1CNC(=O)c1c(OC)cc(O)c2c1OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US20150232474A1,1,C=O.COc1ccc(CNc2nc(N3CCC4(CC4)C3)ncc2C(=O)NCCN2CCNCC2)cc1Cl>>COc1ccc(CNc2nc(N3CCC4(CC4)C3)ncc2C(=O)NCCN2CCN(C)CC2)cc1Cl -US04584008,1,CC(Cl)C#N.c1nc[nH]n1>>CC(C#N)n1cncn1 -US06784174B1,1,Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1N.Cc1csc2ncnc(Cl)c12>>Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1Nc1ncnc2scc(C)c12 -US20060183909A1,3,COC(=O)c1cc(OS(=O)(=O)C(F)(F)F)c2cccc([N+](=O)[O-])c2n1.OB(O)c1ccccc1>>COC(=O)c1cc(-c2ccccc2)c2cccc([N+](=O)[O-])c2n1 -US06413995B1,3,COC(=O)CBr.COc1ccc(COC(=O)C=Cc2ccc(C=O)cc2)cc1>>COC(=O)CC(O)c1ccc(C=CC(=O)OCc2ccc(OC)cc2)cc1 -US20070032475A1,2,CN1CCC2(CCNCC2)CC1.O=C(O)c1cccc(N2Cc3cccc(Cl)c3C2=O)c1>>CN1CCC2(CC1)CCN(C(=O)c1cccc(N3Cc4cccc(Cl)c4C3=O)c1)CC2 -US20020198197A1,9,CCOC(=O)c1nc(-c2cccc(C3=Nc4ccc(-n5cccc5)cc4NC(=O)C3)c2)cs1.N>>NC(=O)c1nc(-c2cccc(C3=Nc4ccc(-n5cccc5)cc4NC(=O)C3)c2)cs1 -US20150030704A1,3,C=C(B1OC(C)(C)C(C)(C)O1)c1ccccc1.Clc1cc(OCc2ccccc2)c(OCc2ccccc2)nn1>>C=C(c1ccccc1)c1cc(OCc2ccccc2)c(OCc2ccccc2)nn1 -US20150057443A1,3,C[Mg+].O=C(CN1CCCCC1)C1(c2ccc(Cl)c(Cl)c2)CCC1>>CC(O)(CN1CCCCC1)C1(c2ccc(Cl)c(Cl)c2)CCC1 -US07820699B2,2,O=C(Br)CBr.O=C(N[C@@H]1CCNC1)c1ccc(Cl)s1>>O=C(N[C@@H]1CCN(C(=O)CBr)C1)c1ccc(Cl)s1 -US20140073799A1,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1.O=C(Cl)CCl>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](NC(=O)CCl)CC1 -US07981882B2,6,CC(C)(C)[Si](C)(C)OC1CN(c2c(Cl)ccc3c2CCN(C(=O)C(F)(F)F)CC3)C1>>O=C(N1CCc2ccc(Cl)c(N3CC(O)C3)c2CC1)C(F)(F)F -US05561141,6,COc1ccc(C(C#N)(CCCCCN2C(=O)c3ccccc3C2=O)SC2CCCCC2)cc1OC>>COc1ccc(C(C#N)(CCCCCN)SC2CCCCC2)cc1OC -US20110230497A1,3,CS(=O)(=O)N1CCC(CC(=O)Nc2ccc(Br)cn2)CC1.OB(O)c1cc(F)cc(F)c1>>CS(=O)(=O)N1CCC(CC(=O)Nc2ccc(-c3cc(F)cc(F)c3)cn2)CC1 -US20080153837A1,1,CN(C)CCCO.Nc1cc(F)c(F)cc1[N+](=O)[O-]>>CN(C)CCCOc1cc(N)c([N+](=O)[O-])cc1F -US07211671B2,1,COC(=O)c1[nH]c(=O)[nH]c1CSc1ccc(O)cc1.Cc1cc(CO)c2ccccc2n1>>COC(=O)c1[nH]c(=O)[nH]c1CSc1ccc(OCc2cc(C)nc3ccccc23)cc1 -US20110003820A1,2,O=C(O)c1cc2ncc(Br)cn2n1.c1cc(-c2nnc3n2CCNC3)co1>>O=C(c1cc2ncc(Br)cn2n1)N1CCn2c(nnc2-c2ccoc2)C1 -US07572809B2,1,CC(C)O.COc1cc2cc(Nc3cc(C)[nH]n3)nc(Cl)c2cc1C(=O)N(C)C>>COc1cc2cc(Nc3cc(C)[nH]n3)nc(OC(C)C)c2cc1C(=O)N(C)C -US08148371B2,2,CO.O=C(Cl)c1cccc(CBr)c1>>COC(=O)c1cccc(CBr)c1 -US05891359,2,CCCCCCCCO.O=C(O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1>>CCCCCCCCOC(=O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1 -US20050261347A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1cccc(F)c1F>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4cccc(F)c4F)c3O2)cc1 -US20110312945A1,7,Cc1c(Cc2ccccc2S(=O)(=O)N2CCCC2)c2c(n1CC(=O)O)CC(C)(C)C(F)(F)C2=O>>Cc1c(Cc2ccccc2S(=O)(=O)N2CCCC2)c2c(n1CC(=O)O)CC(C)(C)C(F)(F)C2 -US20080045493A1,2,CCCN1CC(c2ccc(N)cc2)C1.C[C@H](CF)c1ccc(S(=O)(=O)Cl)cc1>>CCCN1CC(c2ccc(NS(=O)(=O)c3ccc([C@H](C)CF)cc3)cc2)C1 -US06063782,1,COC(=O)c1[nH]c(C)c(C)c1C=O.CS(=O)(=O)OCC=CC(F)(F)F>>COC(=O)c1c(C=O)c(C)c(C)n1CC=CC(F)(F)F -US06180650B2,7,O=[N+]([O-])c1ccc(Oc2ccc(C(Cc3ccncc3)c3ccc(OC(F)F)c(OC(F)F)c3)cn2)cc1>>Nc1ccc(Oc2ccc(C(Cc3ccncc3)c3ccc(OC(F)F)c(OC(F)F)c3)cn2)cc1 -US20150225345A1,6,COC(=O)c1ccc(C#Cc2cccc(F)c2)cn1>>O=C(O)c1ccc(C#Cc2cccc(F)c2)cn1 -US06133271,1,Fc1ccc(CNc2nc(Cl)nc3sc4c(c23)CCCC4)cc1.c1c[nH]cn1>>Fc1ccc(CNc2nc(-n3ccnc3)nc3sc4c(c23)CCCC4)cc1 -US07691850B2,2,COc1ccc2ncc(F)c(CCN3C[C@H](CN)[C@H](O)C3)c2n1.O=C1COc2ccc(C(=O)O)nc2N1>>COc1ccc2ncc(F)c(CCN3C[C@H](CNC(=O)c4ccc5c(n4)NC(=O)CO5)[C@H](O)C3)c2n1 -US20050164989A1,6,NP(N)(=O)N1CCC[C@H](N(Cc2ccccc2)C(=O)OCc2ccccc2)C1=O>>NP(N)(=O)N1CCC[C@H](NCc2ccccc2)C1=O -US05312814,1,CCOC(=O)C(F)Br.CCOP(OCC)OCC>>CCOC(=O)C(F)P(=O)(OCC)OCC -US06271249B1,1,COC(=O)c1cc(Br)ccc1OC.c1c[nH]cn1>>COC(=O)c1cc(-n2ccnc2)ccc1OC -US07812040B2,1,C1CCNC1.Cc1cc(O)ccc1C=O>>Cc1cc(O)ccc1CN1CCCC1 -US20070043076A1,3,CC(C)Oc1ccc(C=O)cc1.O=C(CC(=O)Nc1cccc(C(F)(F)F)c1)Nc1cccc(C(F)(F)F)c1>>CC(C)Oc1ccc(C=C(C(=O)Nc2cccc(C(F)(F)F)c2)C(=O)Nc2cccc(C(F)(F)F)c2)cc1 -US20070208005A1,6,CNC(=O)c1ccc(OCc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)nc1>>CNC(=O)c1ccc(OCc2ccc3c(c2)CCNCC3)nc1 -US20110257151A1,6,COC(=O)c1cccc2c1NC(c1cccc(C(=O)NC3CCN(C)C3)c1)C(C)(C)C2>>CN1CCC(NC(=O)c2cccc(C3Nc4c(cccc4C(=O)O)CC3(C)C)c2)C1 -US20030186970A1,1,CC=O.O=[N+]([O-])c1ccc2c(c1)OCCN2>>CCN1CCOc2cc([N+](=O)[O-])ccc21 -US20060194836A1,1,BrCc1ccncc1.O=C(O)c1cccnc1S>>O=C(O)c1cccnc1SCc1ccncc1 -US08183262B2,3,Cc1cc(-c2ccc(Cl)cc2)nc(-n2cnc(Br)c2)n1.OB(O)c1cccnc1>>Cc1cc(-c2ccc(Cl)cc2)nc(-n2cnc(-c3cccnc3)c2)n1 -US20080064677A9,3,O=Cc1ccc(Br)cc1.OB(O)c1cc2cc(N3CCCCC3)ccc2o1>>O=Cc1ccc(-c2cc3cc(N4CCCCC4)ccc3o2)cc1 -US20090082464A1,9,CC(C)(CCCOC(=O)c1ccccc1)COS(=O)(=O)CCCN=[N+]=[N-]>>CC(C)(CCCOC(=O)c1ccccc1)COS(=O)(=O)CCCN -US20050282812A1,7,CCOC(=O)N1c2ccccc2N(C(C(=O)OC)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC>>CCOC(=O)N1c2ccccc2N(C(CO)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC -US07767674B2,6,Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(OC2CCNCC2)cc1 -US05607947,1,C1CCC(N2CCNCC2)CC1.CS(=O)(=O)OCC[C@@]1(c2ccc(Cl)c(Cl)c2)CCN(C(=O)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1>>O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@](CCN2CCN(C3CCCCC3)CC2)(c2ccc(Cl)c(Cl)c2)C1 -US20020165275A1,2,Nc1cc(Nc2cccc(C(F)(F)F)c2)cc(N(C=O)c2cc(Cl)cc(Cl)c2)c1.S=C=Nc1cc(Cl)cc(Cl)c1>>O=CN(c1cc(Cl)cc(Cl)c1)c1cc(NC(=S)Nc2cc(Cl)cc(Cl)c2)cc(Nc2cccc(C(F)(F)F)c2)c1 -US06838478B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)Cc1cccc(N)c1>>CCOC(=O)Cc1cccc(NC(=O)OC(C)(C)C)c1 -US20120035139A9,7,COC(=O)c1ccc(Cl)c(OCc2ccccc2)c1>>OCc1ccc(Cl)c(OCc2ccccc2)c1 -US08697877B2,6,COC(=O)C(C)(C)c1cc(F)ccc1Br>>CC(C)(C(=O)O)c1cc(F)ccc1Br -US20120238541A1,6,Cn1cc2ccc3c(=O)c(-c4ccc(C5(NC(=O)OC(C)(C)C)CCC5)cc4)c(-c4ccccc4)oc3c2n1>>Cn1cc2ccc3c(=O)c(-c4ccc(C5(N)CCC5)cc4)c(-c4ccccc4)oc3c2n1 -US20140275456A1,2,CC(O)CC(C)O.O=C(Cl)c1ccccc1>>CC(O)CC(C)OC(=O)c1ccccc1 -US20120282629A1,1,CN(N)c1ccc(C(F)(F)F)cc1[N+](=O)[O-].O=Cc1c(O)cc(O)cc1O>>CN(N=Cc1c(O)cc(O)cc1O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-] -US08455484B2,2,COCCNCc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1.O=CO>>COCCN(C=O)Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1 -US20100216746A1,9,[N-]=[N+]=NCc1ccc(Cl)c(Oc2cc(Br)cc(F)c2Cl)c1F>>NCc1ccc(Cl)c(Oc2cc(Br)cc(F)c2Cl)c1F -US20120289500A1,2,Nn1nc(-c2ccccn2)c2ccccc2c1=O.O=C(O)Cc1cc(F)cc(F)c1>>O=C(Cc1cc(F)cc(F)c1)Nn1nc(-c2ccccn2)c2ccccc2c1=O -US20020188120A1,6,CCCCN1CCC(C(=O)OCC)(S(=O)(=O)c2ccc(OCCC(C)C)cc2)CC1>>CCCCN1CCC(C(=O)O)(S(=O)(=O)c2ccc(OCCC(C)C)cc2)CC1 -US20090270361A1,2,COCCN.Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Cc1ccc(C(=O)O)cc1>>COCCNC(=O)c1ccc(Cc2c(C)nn(-c3ccc(C#N)c(Cl)c3)c2C)cc1 -US20150232444A1,2,CC1CCN(C2CCNCC2)CC1.Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Cl>>Cc1cc(Cl)cc(Cl)c1S(=O)(=O)N1CCC(N2CCC(C)CC2)CC1 -US08163906B2,6,COC(=O)c1ccc(Cc2c(C(=O)OC)n(-c3ccccc3)c3nc(C)ccc3c2=O)cn1>>COC(=O)c1c(Cc2ccc(C(=O)O)nc2)c(=O)c2ccc(C)nc2n1-c1ccccc1 -US20090048252A1,3,O=C1CSC(Nc2c(Cl)cccc2Cl)=N1.O=Cc1ccc([N+](=O)[O-])c(O)c1>>O=C1N=C(Nc2c(Cl)cccc2Cl)S/C1=C\c1ccc([N+](=O)[O-])c(O)c1 -US08389555B2,8,O=C(NCCCCO)C1Cc2ccccc2C1>>O=CCCCNC(=O)C1Cc2ccccc2C1 -US06107458,1,CC(C)(C)OC(=O)N1Cc2cc(O)ccc2C[C@H]1C(=O)O.CCCCCCCCBr>>CCCCCCCCOc1ccc2c(c1)CN(C(=O)OC(C)(C)C)[C@H](C(=O)O)C2 -US20130303533A1,1,BrC1CCCC1.N#Cc1c[nH]nc1N>>N#Cc1cn(C2CCCC2)nc1N -US05006570,2,NCC1CCCN1CC1=CCCCC1.O=C(O)c1cc(Cl)cc2c1OCC2>>O=C(NCC1CCCN1CC1=CCCCC1)c1cc(Cl)cc2c1OCC2 -US04085129,2,O=C(Cl)Cl.Oc1ccccc1>>O=C(Cl)Oc1ccccc1 -US20150011511A1,1,CC(=Cc1ccc(C(=O)O)s1)C(=O)OC(C)(C)C.N=C(N)c1ccc(O)cc1>>CC(=Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)OC(C)(C)C -US20120295874A1,3,C=CC(=O)OC.COc1nc(C)c(I)c(OC)n1>>COC(=O)C=Cc1c(C)nc(OC)nc1OC -US20070238775A1,2,CNCc1ccccc1.O=C(Cl)C(=O)c1c[nH]c2ccccc12>>CN(Cc1ccccc1)C(=O)C(=O)c1c[nH]c2ccccc12 -US07618990B2,1,CI.O=C1NCCN1c1nc(-c2ccc(Br)cc2)cs1>>CN1CCN(c2nc(-c3ccc(Br)cc3)cs2)C1=O -US20120295897A1,1,Cc1cccc(CO)n1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCO3>>Cc1cccc(CN2C(=O)C3(COc4cc5c(cc43)OCCO5)c3ccccc32)n1 -US20070191420A1,2,CC(C)(C)CC(=O)c1ccc(C(=O)O)cc1.Nc1ccncc1>>CC(C)(C)CC(=O)c1ccc(C(=O)Nc2ccncc2)cc1 -US20040209921A1,2,CC(=O)OC(C)(C)c1cccnc1CN(CCCCN)Cc1ncc(C)cc1C.C[Si](C)(C)N=C=O>>CC(=O)OC(C)(C)c1cccnc1CN(CCCCNC(N)=O)Cc1ncc(C)cc1C -US06716847B2,1,COc1cc2ncnc(Cl)c2cc1OC.N#Cc1ccc(C(=O)Nc2cccc(N)c2)cc1>>COc1cc2ncnc(Nc3cccc(NC(=O)c4ccc(C#N)cc4)c3)c2cc1OC -US20130005707A1,1,Brc1cnc2nc[nH]c2c1.C[Si](C)(C)CCOCCl>>C[Si](C)(C)CCOCn1cnc2ncc(Br)cc21 -US20050187228A1,1,COc1cc(C=O)cc(OC)c1OC.NCCNc1nc(Cl)nc2c1ncn2C1CCCC1>>COc1cc(CNCCNc2nc(Cl)nc3c2ncn3C2CCCC2)cc(OC)c1OC -US07482448B2,6,COC(=O)[C@H](CC(F)(F)Cc1ccccc1)NC(=O)N1CCOCC1>>O=C(O)[C@H](CC(F)(F)Cc1ccccc1)NC(=O)N1CCOCC1 -US04959364,2,C=CC(=O)Cl.COC(=O)[C@@H]1CCCN1>>C=CC(=O)N1CCCC1C(=O)OC -US20110046378A1,1,C=O.Nc1ccc2c(c1)[nH]c1cc(OCCOCCOCCF)ccc12>>CNc1ccc2c(c1)[nH]c1cc(OCCOCCOCCF)ccc12 -US20070254866A1,9,CCOC(=O)c1cn(C2CC2)c2c(OC)c(F)c(F)c([N+](=O)[O-])c2c1=O.[NH4+]>>CCOC(=O)c1cn(C2CC2)c2c(OC)c(F)c(N)c([N+](=O)[O-])c2c1=O -US20100004280A1,3,CCOC(=O)C1(Cc2ccc(Br)cc2)CCC(=O)N1.Fc1ccc(Br)nc1>>CCOC(=O)C1(Cc2ccc(-c3ccc(F)cn3)cc2)CCC(=O)N1 -US08202881B2,4,CCCC(=O)CBr.CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(N)=S)nc21>>CCCc1csc(Nc2nc3c(cc(C(=O)N(C4CC4)C4CC4)n3CC)c3c2ncn3C)n1 -US20110039821A1,1,CCOC(=O)c1cc(O)c2cc(C)oc2c1.CS(=O)(=O)c1ccc(Br)nc1>>CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cn2)c2cc(C)oc2c1 -US20030176495A1,1,CC1(C)OC(=O)C(=CC(=O)Cl)O1.CONCc1ccc(NC(C)=O)cc1>>CON(Cc1ccc(NC(C)=O)cc1)C(=O)C=C1OC(C)(C)OC1=O -US20090066238A1,6,c1ccc(Cn2c3ccccc3c3cc(COCCCCCCOCc4ccc(N(c5ccccc5)c5ccccc5)cc4)ccc32)cc1>>c1ccc(N(c2ccccc2)c2ccc(COCCCCCCOCc3ccc4[nH]c5ccccc5c4c3)cc2)cc1 -US20100099681A1,7,Nc1cc(Cl)c(Br)cc1[N+](=O)[O-]>>Nc1cc(Cl)c(Br)cc1N -US07148228B2,1,COc1c(C)c(Cl)nc(CCl)c1C.Nc1nc(Cl)c2cn[nH]c2n1>>COc1c(C)c(Cl)nc(Cn2ncc3c(Cl)nc(N)nc32)c1C -US20090105234A1,3,CC(C)(O)c1cccc(I)c1.CCOC(=O)C(F)(F)Br>>CCOC(=O)C(F)(F)c1cccc(C(C)(C)O)c1 -US05190689,1,C=CCOC(=O)CCCCCCCCBr.CCCCCc1ccc(-c2ccc(CC(O)C3CCC(CCC)CC3)cc2)cc1>>C=CCOC(=O)CCCCCCCCOC(Cc1ccc(-c2ccc(CCCCC)cc2)cc1)C1CCC(CCC)CC1 -US20070004771A1,1,CCNc1c([N+](=O)[O-])cnc(Cl)c1Br.Oc1ccc(F)cc1>>CCNc1c([N+](=O)[O-])cnc(Oc2ccc(F)cc2)c1Br -US20090215742A1,2,O=C(O)c1ccc(C(F)(F)F)cc1O.c1ccc2c(c1)CNC2>>O=C(c1ccc(C(F)(F)F)cc1O)N1Cc2ccccc2C1 -US04469869,9,CN1CCC(C(=O)c2ccccc2F)CC1.NO>>CN1CCC(C(=NO)c2ccccc2F)CC1 -US20090227560A1,2,COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)O)c1-c1ccccc1.O=C(OCc1ccccc1)N1CCN[C@H](CCn2[nH]c(=O)c3ccccc32)C1>>COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCN(C(=O)OCc3ccccc3)C[C@H]2CCn2[nH]c(=O)c3ccccc32)c1-c1ccccc1 -US20100272680A1,9,N#C[Cu].O=C(c1nc2c(C(F)(F)F)cc(C3CC3)cn2c1Br)N1CCC(N2CCOC2=O)CC1>>N#Cc1c(C(=O)N2CCC(N3CCOC3=O)CC2)nc2c(C(F)(F)F)cc(C3CC3)cn12 -US20060223826A1,1,C=O.C[C@@H](c1c[nH]c2ccccc12)[C@@H](NC(=O)N1CCC(c2ccccc2)CC1)C(=O)Nc1ccc2c(c1)CNCC2>>C[C@@H](c1c[nH]c2ccccc12)[C@@H](NC(=O)N1CCC(c2ccccc2)CC1)C(=O)Nc1ccc2c(c1)CN(C)CC2 -US20090069282A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.Clc1cc(Br)ccc1OCCN1CCCC1>>Clc1ccc(-c2ccc(C#Cc3ccc(OCCN4CCCC4)c(Cl)c3)nc2)cc1 -US20090029981A1,6,COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)C[C@@H](CO)[C@@H]3c3ccc(OC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)C[C@@H](CO)[C@@H]3c3ccc(O)cc3)cc21 -US20090163586A1,7,NS(=O)(=O)c1ccccc1NS(=O)(=O)/C=C/c1ccccc1-c1ccc2cccc-2o1>>NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccccc1-c1ccc2cccc-2o1 -US06987114B1,1,CCc1c(Sc2cc(C)cc(C)c2)[nH]c(=O)[nH]c1=O.Fc1cc(F)cc(CBr)c1>>CCc1c(Sc2cc(C)cc(C)c2)n(Cc2cc(F)cc(F)c2)c(=O)[nH]c1=O -US20110034507A1,3,CCOC(=O)c1cccc(I)c1.COc1ccc2sc(B(O)O)cc2c1>>CCOC(=O)c1cccc(-c2cc3cc(OC)ccc3s2)c1 -US05190959,1,ClC(c1cccs1)c1cccs1.O=[N+]([O-])c1ccccc1OCCCN1CCC(O)CC1>>O=[N+]([O-])c1ccccc1OCCCN1CCC(OC(c2cccs2)c2cccs2)CC1 -US20100305066A1,1,Ic1cn[nH]c1.O=C(Cl)c1ccccc1>>O=C(c1ccccc1)n1cc(I)cn1 -US20080318954A1,4,CC(=O)C(Cl)C(C)=O.NC(=S)c1ccnc(Nc2ccc(Cl)cc2)n1>>CC(=O)c1sc(-c2ccnc(Nc3ccc(Cl)cc3)n2)nc1C -US20090281092A1,2,CCOc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C.CN1CCC(N)CC1>>CCOc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20100311966A1,2,CCOC(=O)c1nc(-c2ccc(N)cc2)oc1CC.CCc1[nH]c(C(=O)O)nc1Cl>>CCOC(=O)c1nc(-c2ccc(NC(=O)c3nc(Cl)c(CC)[nH]3)cc2)oc1CC -US20040038239A1,7,C#Cc1ccc2ccnc(Cc3ccc(CCCC)cc3)c2c1>>CCCCc1ccc(Cc2nccc3ccc(CC)cc23)cc1 -US20140057953A1,6,COc1ccc(-c2ccc(C(=O)N(C)Cc3ccccc3)s2)cc1>>CN(Cc1ccccc1)C(=O)c1ccc(-c2ccc(O)cc2)s1 -US08426411B2,1,BrCc1ccccc1.COC(=O)C12CCC(NC(=O)OC(C)(C)C)(CC1)CC2>>COC(=O)C12CCC(N(Cc3ccccc3)C(=O)OC(C)(C)C)(CC1)CC2 -US20120232096A1,1,CCc1ccc(Br)cc1.Cc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)(C)C2>>CCc1ccc(N2CCN(c3c(C)c(C)c4c(c3C)CC(C)(C)O4)CC2)cc1 -US20080280875A1,6,COC(=O)c1cc(OC)cc2cc(C)oc12>>COC(=O)c1cc(O)cc2cc(C)oc12 -US20060030609A1,9,COC(=O)[C@H]1CN(c2ccc3c(c2)CC(=O)N3C(C)(C)C)C(=O)O1.N>>CC(C)(C)N1C(=O)Cc2cc(N3C[C@H](C(N)=O)OC3=O)ccc21 -US20110105544A1,1,CC(=O)OCBr.CNS(=O)(=O)c1cccc(CCCC(CCc2ccccc2)C(=O)O)c1>>CNS(=O)(=O)c1cccc(CCCC(CCc2ccccc2)C(=O)OCOC(C)=O)c1 -US05935966,9,CCOC(=O)c1cnc(Cl)nc1-c1ccccc1.NN>>CCOC(=O)c1cnc(NN)nc1-c1ccccc1 -US04894369,6,CC(=O)O[C@H]1C[C@@H]2CC[C@H]3[C@@H]4C[C@H](N5CCCC5)[C@H](OC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)C[C@@H]1N1CCOCC1>>CC(=O)O[C@H]1C[C@@H]2CC[C@H]3[C@@H]4C[C@H](N5CCCC5)[C@H](O)[C@@]4(C)CC[C@@H]3[C@@]2(C)C[C@@H]1N1CCOCC1 -US20120149691A1,1,N#Cc1cnn2cc([N+](=O)[O-])cc2c1Cl.Nc1ccccc1>>N#Cc1cnn2cc([N+](=O)[O-])cc2c1Nc1ccccc1 -US05356894,2,CC(C)(C)C(=O)Cl.Nc1nc(NCCc2ccc(O)cc2)nc2nc(-c3ccco3)nn12>>CC(C)(C)C(=O)Oc1ccc(CCNc2nc(N)n3nc(-c4ccco4)nc3n2)cc1 -US20090275566A1,3,CC1(C)C[C@@](C)(c2ccc(F)c(Br)c2)N=C(NC(=O)c2ccccc2)S1.OB(O)c1cncnc1>>CC1(C)C[C@@](C)(c2ccc(F)c(-c3cncnc3)c2)N=C(NC(=O)c2ccccc2)S1 -US20050171350A1,6,COC(=O)c1cncc(OC)n1>>COc1cncc(C(=O)O)n1 -US07745438B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]1N[C@@H]([C@H](OCc2ccccc2)[C@H](Cc2cc(F)cc(F)c2)N(Cc2ccccc2)Cc2ccccc2)CO[C@H]1OCC(C)(C)C>>C[C@H]1[C@H](OCC(C)(C)C)OC[C@H]([C@@H](OCc2ccccc2)[C@H](Cc2cc(F)cc(F)c2)N(Cc2ccccc2)Cc2ccccc2)N1C(=O)OC(C)(C)C -US06174877B1,4,C#CCCO.[N-]=[N+]=NC(c1ccccc1)(c1ccccc1)c1ccccc1>>OCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)nn1 -US20110092505A1,2,COC(=O)Nc1cc(Cl)nc(N2CCN(C(=O)OC(C)(C)C)CC2)c1.Nc1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2cc(NC(=O)Nc3ccccc3)cc(Cl)n2)CC1 -US20070149583A1,2,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.COC(=O)C(N)Cc1c[nH]c2c(Br)cccc12>>COC(=O)C(Cc1c[nH]c2c(Br)cccc12)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C -US20090197959A1,3,CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1.O=Cc1cc(C(F)(F)F)ccc1Br>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2C=O)c1 -US20150225397A1,6,COC(=O)c1cccc([C@]23C=C(C#N)C(=O)[C@@H](C)[C@@H]2CCc2cnc(-c4ccccc4)nc23)c1>>C[C@@H]1C(=O)C(C#N)=C[C@]2(c3cccc(C(=O)O)c3)c3nc(-c4ccccc4)ncc3CC[C@@H]12 -US20110028469A1,2,COC(=O)c1sccc1N.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1 -US06608072B1,1,CCOC(=O)N1CCC(c2nc(-c3ccc(F)cc3)c(-c3ccnc(F)c3)s2)CC1.C[C@H](N)c1ccccc1>>CCOC(=O)N1CCC(c2nc(-c3ccc(F)cc3)c(-c3ccnc(N[C@@H](C)c4ccccc4)c3)s2)CC1 -US07226927B2,1,COc1ccc(C(=O)O)cc1N.FC(F)(F)c1cc(Cl)nc(-c2cnccn2)n1>>COc1ccc(C(=O)O)cc1Nc1cc(C(F)(F)F)nc(-c2cnccn2)n1 -US20100087424A1,6,O=C(NC[C@H]1CN(C[C@@H]2COc3c(F)ccc4ccc(=O)n2c34)C[C@H]1O)OCc1ccccc1>>NC[C@H]1CN(C[C@@H]2COc3c(F)ccc4ccc(=O)n2c34)C[C@H]1O -US08329682B2,3,CC(C)(O)C(=O)Nc1cc2c(cc1F)CC(=O)N2.CCN(CC)CCN1CCCc2[nH]c(C=O)c(C)c2C1=O>>CCN(CC)CCN1CCCc2[nH]c(/C=C3\C(=O)Nc4cc(NC(=O)C(C)(C)O)c(F)cc43)c(C)c2C1=O -US20040097563A1,2,CC(C)(C)OC(=O)c1c(-c2cccc(N)c2)cc(-c2ccccc2O)nc1N.O=C1CCC(C(=O)Cl)O1>>CC(C)(C)OC(=O)c1c(-c2cccc(NC(=O)C3CCC(=O)O3)c2)cc(-c2ccccc2O)nc1N -US20040132727A1,2,CCC(Oc1ccccc1)C(=O)N=C=S.COc1cc2nccc(Oc3ccc(N)cc3Cl)c2cc1OC>>CCC(Oc1ccccc1)C(=O)NC(=S)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(Cl)c1 -US08383643B2,4,N#Cc1nnc(Br)s1.[N-]=[N+]=[N-]>>Brc1nnc(-c2nnn[nH]2)s1 -US09018224B2,1,COC(=O)Cc1ccc(O)cc1F.COCc1cnc(N2CCC([C@H]3C[C@H]3CCO)CC2)nc1>>COCc1cnc(N2CCC([C@H]3C[C@H]3CCOc3ccc(CC(=O)OC)c(F)c3)CC2)nc1 -US07625948B2,2,CCOC(=O)C(CO)(C(=O)OCC)c1ccccc1.O=C(O)CN1CCC(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1>>CCOC(=O)C(COC(=O)CN1CCC(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)(C(=O)OCC)c1ccccc1 -US03997536,9,CCCCCCCOc1ccc(-c2ncc(C#N)c(Cl)n2)cc1>>CCCCCCCOc1ccc(-c2ncc(C#N)cn2)cc1 -US06949536B2,1,CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3ccco3)cc2)cc1CCl.O=C1NC(=O)c2ccccc21>>CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3ccco3)cc2)cc1CN1C(=O)c2ccccc2C1=O -US07803825B2,3,CC1(C)OB(c2ccc(-n3cnc4ccccc43)cc2)OC1(C)C.COC(=O)c1cnc(Br)n1C>>COC(=O)c1cnc(-c2ccc(-n3cnc4ccccc43)cc2)n1C -US20150252032A1,6,COC(=O)c1cc(OC)c(C)cc1-c1ncccn1>>COc1cc(C(=O)O)c(-c2ncccn2)cc1C -US20150246922A1,3,Cc1c2n(c3c(Br)cc(F)cc13)CCNC2=O.OB(O)c1ccc(Cl)nc1>>Cc1c2n(c3c(-c4ccc(Cl)nc4)cc(F)cc13)CCNC2=O -US09062013B2,2,CC1(C)[C@@H](C(=O)O)[C@@H]1c1ccccc1.Nc1cc(C(F)(F)F)n[nH]1>>CC1(C)[C@@H](C(=O)Nc2cc(C(F)(F)F)n[nH]2)[C@@H]1c1ccccc1 -US20100035934A1,6,CCOC(=O)c1ccn(-c2cccc(Nc3ccc(Cl)cc3)n2)n1>>O=C(O)c1ccn(-c2cccc(Nc3ccc(Cl)cc3)n2)n1 -US20110028501A1,1,CS(=O)(=O)c1ccc(Br)nc1.OCC[C@@H]1C[C@@H]1C1CCN(c2ncc(Cl)cn2)CC1>>CS(=O)(=O)c1ccc(OCC[C@H]2C[C@H]2C2CCN(c3ncc(Cl)cn3)CC2)nc1 -US20050143379A1,9,N#Cc1cc(F)c(Cl)cc1O[C@H](CN=[N+]=[N-])c1ccccc1>>N#Cc1cc(F)c(Cl)cc1O[C@H](CN)c1ccccc1 -US20150065482A1,3,C#C[C@@](C)(O)c1ncccn1.COC(=O)c1nn(-c2cccc(Br)c2)c2ccccc12>>COC(=O)c1nn(-c2cccc(C#C[C@@](C)(O)c3ncccn3)c2)c2ccccc12 -US04598079,9,N.O=C1NCCN(C(=O)CCl)C1c1cccs1>>NCC(=O)N1CCNC(=O)C1c1cccs1 -US04304727,9,C[C@]12C[C@H](O)[C@@]3(Br)[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CCC2=O>>C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)C(=O)CC[C@@H]12 -US20110112082A1,1,C=CCC(O)(CCCl)c1ccc(F)cc1.CN(N)c1ccccc1>>C=CCC(O)(CCNN(C)c1ccccc1)c1ccc(F)cc1 -US08524724B2,7,CC(C)NC(=O)N=S(C)(=O)c1cccc([N+](=O)[O-])c1>>CC(C)NC(=O)N=S(C)(=O)c1cccc(N)c1 -US20140213586A1,9,CC(C)Oc1cncc(Br)c1.[NH4+]>>CC(C)Oc1cncc(N)c1 -US07452892B2,1,CCNC1(C(N)=O)CN(c2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c3n[nH]c(=O)n23)C1.CI>>CCNC1(C(N)=O)CN(c2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c3nn(C)c(=O)n23)C1 -US05262537,2,CC(=O)Cl.COc1ccccc1NC(=O)[C@@H]1Cc2[nH]cnc2CN1>>COc1ccccc1NC(=O)[C@@H]1Cc2[nH]cnc2CN1C(C)=O -US20150045378A1,6,Cc1ccc(C(=O)OCc2ccccc2)cc1OCc1ccccc1>>Cc1ccc(C(=O)O)cc1OCc1ccccc1 -US05294612,1,CCI.Nc1ccc(C(=O)O)cn1>>CCOC(=O)c1ccc(N)nc1 -US05208247,2,CC(=O)OC(C)=O.CCCCCCCCCCCCCCOc1ccc(COC(=O)NCc2ccccn2)cc1>>CCCCCCCCCCCCCCOc1ccc(COC(=O)N(Cc2ccccn2)C(C)=O)cc1 -US06245790B1,9,COc1cccc(C(O)C2CCCCC2=O)c1C>>COc1cccc(CC2CCCCC2=O)c1C -US08557805B2,6,CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cn3)cc(OC3CCOCC3)c2[nH]1>>CS(=O)(=O)c1ccc(Oc2cc(OC3CCOCC3)c3[nH]c(C(=O)O)cc3c2)nc1 -US20150203486A1,9,Cc1nc2ccc(-c3cnn(C)c3)cn2c1C(O)c1cc(Cl)ccc1Cl>>Cc1nc2ccc(-c3cnn(C)c3)cn2c1Cc1cc(Cl)ccc1Cl -US20080275085A1,1,Cc1cc(F)ccc1[C@H]1CNCC[C@@H]1C(=O)N(C)[C@H](C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.NC(=O)CI>>Cc1cc(F)ccc1[C@H]1CN(CC(N)=O)CC[C@@H]1C(=O)N(C)[C@H](C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20100087427A1,2,CCNC1CCCCC1.O=C(Cl)CCl>>CCN(C(=O)CCl)C1CCCCC1 -US08933105B2,2,O=Cc1c[nH]c(-c2cccnc2F)c1.O=S(=O)(Cl)c1ccco1>>O=Cc1cc(-c2cccnc2F)n(S(=O)(=O)c2ccco2)c1 -US05047577,1,CC(=O)OCCBr.CCCCCCCCCCCCCCN(C)C>>CCCCCCCCCCCCCC[N+](C)(C)CCOC(C)=O -US20130040930A1,1,Cc1ccc(N2CCN(C(=O)c3ccc(Br)cc3)CC2)c(C)c1.O=C1C[C@H](O)CN1>>Cc1ccc(N2CCN(C(=O)c3ccc(N4C[C@@H](O)CC4=O)cc3)CC2)c(C)c1 -US08101775B2,3,COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(C#N)c1.OB(O)c1ccccc1>>COC(=O)c1ccc(-c2ccccc2)c(C#N)c1 -US07273877B2,2,Cc1ccc(Nc2cc(=O)n(C)cc2C(=O)O)c(F)c1.NCCCO>>Cc1ccc(Nc2cc(=O)n(C)cc2C(=O)NCCCO)c(F)c1 -US20080171748A1,2,CNC.COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@H](CC(C)(C)C(=O)O)C[C@@H]3c3ccc(OC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@H](CC(C)(C)C(=O)N(C)C)C[C@@H]3c3ccc(OC)cc3)cc21 -US05438053,1,C1=COCCC1.COc1ccc(COc2coc(CO)cc2=O)cc1>>COc1ccc(COc2coc(COC3CCCCO3)cc2=O)cc1 -US04629794,7,CC(=O)c1cn(C(=O)OCc2ccccc2)c2ccccc12>>CC(O)c1cn(C(=O)OCc2ccccc2)c2ccccc12 -US20090275606A1,6,CCOC(=O)c1c(Nc2ccc(Br)cc2F)cc(=O)n2c1CCC2>>O=C(O)c1c(Nc2ccc(Br)cc2F)cc(=O)n2c1CCC2 -US04021552,1,O=C(c1ccc(F)cc1)C1CCNCC1.OCCCCl>>O=C(c1ccc(F)cc1)C1CCN(CCCO)CC1 -US05539112,1,C1=COCCC1.CC(C)(C)C(=O)Nc1cc(O)c(F)c(F)c1F>>CC(C)(C)C(=O)Nc1cc(OC2CCCCO2)c(F)c(F)c1F -US20120029190A1,6,COc1ccc(Cn2c(-c3ccccn3)nc3c2CN(c2cc(F)cc(C#N)c2)CC3)cc1>>N#Cc1cc(F)cc(N2CCc3nc(-c4ccccn4)[nH]c3C2)c1 -US06133266,6,CCOC(=O)C(O)c1ccc(OCc2ccccc2)c(CCOCc2ccccc2)c1>>O=C(O)C(O)c1ccc(OCc2ccccc2)c(CCOCc2ccccc2)c1 -US08080571B2,1,CC(C)Cc1cc(-c2cccc(CBr)c2)c(S(=O)(=O)NC(C)(C)C)s1.Cc1ncc[nH]1>>Cc1nccn1Cc1cccc(-c2cc(CC(C)C)sc2S(=O)(=O)NC(C)(C)C)c1 -US20100305133A1,6,CCOC(=O)CNC(=O)c1c(O)ccc2nc(NCc3ccccc3)c(-c3ccccc3)nc12>>O=C(O)CNC(=O)c1c(O)ccc2nc(NCc3ccccc3)c(-c3ccccc3)nc12 -US20100093756A1,9,COC(=O)c1ccc(C2CC2)o1.[NH4+]>>NC(=O)c1ccc(C2CC2)o1 -US20140162985A1,1,CC[C@@]12CC[C@](O)(C(F)(F)F)C[C@H]1CCCc1cc3c(cnn3-c3ccc(F)cc3)cc12.C[S-]>>CC[C@@]12CC[C@](O)(C(F)(F)F)C[C@H]1CCCc1cc3c(cnn3-c3ccc(SC)cc3)cc12 -US20060178510A1,6,CC(C)(C)OC(=O)N1CCO[C@H](Cc2cc(Br)ccc2OC(F)F)C1>>FC(F)Oc1ccc(Br)cc1C[C@@H]1CNCCO1 -US20150057260A1,9,CCOC(=O)c1nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)nc2cc(F)ccc12.N>>CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)c4ccc(F)cc4n3)c2)C1=O -US08664214B2,1,NCc1ccccc1.O=C(O)c1cnccc1Cl>>O=C(O)c1cnccc1NCc1ccccc1 -US04432976,6,CC(=O)OCC(=O)[C@@]12OCO[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]12C>>C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1C[C@H]1OCO[C@]12C(=O)CO -US04144341,7,O=[N+]([O-])c1cnc(Nc2ccccc2F)c([N+](=O)[O-])c1>>Nc1cc([N+](=O)[O-])cnc1Nc1ccccc1F -US20130203713A1,2,O=C(O)CCc1ccc(Oc2ccc(O)cc2)cc1.OCCc1ccc(O)cc1>>O=C(CCc1ccc(Oc2ccc(O)cc2)cc1)OCCc1ccc(O)cc1 -US07902367B2,1,COC(=O)c1ccccc1F.O=C(OCc1ccccc1)C1CCCNC1>>COC(=O)c1ccccc1N1CCCC(C(=O)OCc2ccccc2)C1 -US20070027178A1,6,Cc1cc(C)c2c(c1)c1c(n2C)CCN(C(=O)OC(C)(C)C)C1>>Cc1cc(C)c2c(c1)c1c(n2C)CCNC1 -US20130072679A1,1,CCI.CCS(=O)(=O)NCc1cncc(Br)c1>>CCN(Cc1cncc(Br)c1)S(=O)(=O)CC -US20150243910A1,3,C#Cc1cccc(-c2nc(CCC)nn2C)c1.Ic1ccc(I)cc1>>CCCc1nc(-c2cccc(C#Cc3ccc(I)cc3)c2)n(C)n1 -US04495187,6,CCc1nnc2c(OC)nc3cc(F)ccc3n12>>CCc1nnc2c(O)nc3cc(F)ccc3n12 -US04725601,1,Cc1ccccc1CCl.Nc1ncccc1O>>Cc1ccccc1COc1cccnc1N -US04097591,2,CCOC(=O)CNCCOC.N=C(N)NCCC[C@H](NS(=O)(=O)c1ccc2sc3ccccc3c2c1)C(=O)Cl>>CCOC(=O)CN(CCOC)C(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c1ccc2sc3ccccc3c2c1 -US20120302598A1,7,CCOC(=O)N(Cc1ccc(C)nc1)c1cc(OCC2CCOCC2)nc(N)c1[N+](=O)[O-]>>CCOC(=O)N(Cc1ccc(C)nc1)c1cc(OCC2CCOCC2)nc(N)c1N -US07279487B2,6,COC(=O)c1c(OCc2ccccc2)c2ncccc2n(Cc2ccccc2)c1=O>>O=C(O)c1c(OCc2ccccc2)c2ncccc2n(Cc2ccccc2)c1=O -US20090029994A1,1,CC(C)(C)OC(=O)CCCBr.COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN(Cc1cc(C#N)cc(C(F)(F)F)c1)c1ccc(O)cn1>>COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN(Cc1cc(C#N)cc(C(F)(F)F)c1)c1ccc(OCCCC(=O)OC(C)(C)C)cn1 -US07045360B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](C(=O)O)c1ccccc1>>CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccccc1 -US20060135554A1,7,CCOc1ccc(CC(=O)Nc2cc(N(C)C(=O)CC(C)C)ccc2[N+](=O)[O-])cc1>>CCOc1ccc(CC(=O)Nc2cc(N(C)C(=O)CC(C)C)ccc2N)cc1 -US20110195932A1,2,CC(=O)Cl.Nc1ccc2oc(SCc3ccc(Cl)cc3)nc2c1>>CC(=O)Nc1ccc2oc(SCc3ccc(Cl)cc3)nc2c1 -US20130225524A1,1,CCOC(=O)c1cccc(N)c1.O=[N+]([O-])c1cnc2cc(Br)ccc2c1O>>CCOC(=O)c1cccc(Nc2c([N+](=O)[O-])cnc3cc(Br)ccc23)c1 -US20150023990A1,2,CC(C)N=C=O.CCCn1c(COCC)nc2c(N)nc3ccc(OC4CCNCC4)cc3c21>>CCCn1c(COCC)nc2c(N)nc3ccc(OC4CCN(C(=O)NC(C)C)CC4)cc3c21 -US08426540B2,1,Nc1ccccc1O.O=Cc1ccc(-c2cccc(Cl)c2)o1>>Oc1ccccc1N=Cc1ccc(-c2cccc(Cl)c2)o1 -US06307085B1,2,COc1ccc([C@@]2(O)CCCC[C@@H]2O)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc([C@@]2(O)CCCC[C@@H]2OS(=O)(=O)c2ccc(C)cc2)cc1 -US20100168243A1,1,CCc1cccc(-c2c(Cl)cccc2Br)c1.COCCCCN>>CCc1cccc(-c2c(Cl)cccc2NCCCCOC)c1 -US20060052392A1,7,Cc1cc2c(cc1C)C(=O)N(c1cccnc1)C2=O>>Cc1cc2c(cc1C)C(O)N(c1cccnc1)C2=O -US20080221210A1,7,COC(=O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>O=[N+]([O-])c1cc(CO)cc(C(F)(F)F)c1 -US06005116,6,COc1ccccc1-c1cc(OCCNC(=O)OC(C)(C)C)no1>>COc1ccccc1-c1cc(OCCN)no1 -US06727387B2,1,CBr.CN(C)C(C)(C)CC(C)(C)C>>CC(C)(C)CC(C)(C)[N+](C)(C)C -US08415345B2,2,CC(C)(C)c1nc(-c2cccc(N)c2F)c(-c2ccnc(N)n2)s1.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3ccccc3)c2F)c(-c2ccnc(N)n2)s1 -US20060004056A1,1,CC(C)(O)c1ccc(Br)cc1.C[Si](C)(C)CCOCCl>>CC(C)(OCOCC[Si](C)(C)C)c1ccc(Br)cc1 -US07192968B2,9,CCOC(=O)[C@@H]1CC[C@@H](N=[N+]=[N-])[C@@H](NC(=O)OC(C)(C)C)C1>>CCOC(=O)[C@@H]1CC[C@@H](N)[C@@H](NC(=O)OC(C)(C)C)C1 -US08367710B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1c(Br)cccc1[N+](=O)[O-]>>COc1c(B2OC(C)(C)C(C)(C)O2)cccc1[N+](=O)[O-] -US20060235074A1,6,CC(C)CCOc1ccc(C(CC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)cc1>>CC(C)CCOc1ccc(C(CC(=O)OCc2ccccc2)C(=O)O)cc1 -US05547967,1,CO.NCCc1ccc([N+](=O)[O-])cc1>>CNCCc1ccc([N+](=O)[O-])cc1 -US20070244125A1,1,Cc1cccc(B(O)O)c1.O=C(c1ccc2[nH]c(C(=O)N3CCS(=O)(=O)CC3)cc2c1)N1CCN(C2CCCC2)CC1>>Cc1cccc(-n2c(C(=O)N3CCS(=O)(=O)CC3)cc3cc(C(=O)N4CCN(C5CCCC5)CC4)ccc32)c1 -US07750020B2,2,CCO.O=C(O)Cc1ccccc1>>CCOC(=O)Cc1ccccc1 -US08304419B2,8,CC(O)c1nc(Br)c(C(=O)NCc2ccc(Cl)c(Oc3cc(Cl)cc(C#N)c3)c2F)[nH]1>>CC(=O)c1nc(Br)c(C(=O)NCc2ccc(Cl)c(Oc3cc(Cl)cc(C#N)c3)c2F)[nH]1 -US20060148858A1,6,CCc1cccc(CC(=O)OC)c1OCCCc1cn(-c2ccc(Br)cn2)nc1C(CC)CC>>CCc1cccc(CC(=O)O)c1OCCCc1cn(-c2ccc(Br)cn2)nc1C(CC)CC -US04874775,2,CCS(=O)(=O)Cl.Fc1ccc(NCc2cccnc2)c(F)c1>>CCS(=O)(=O)N(Cc1cccnc1)c1ccc(F)cc1F -US07435735B2,2,CNCC(OC)OC.O=C(O)CNC(=O)OCc1ccccc1>>COC(CN(C)C(=O)CNC(=O)OCc1ccccc1)OC -US20060058528A1,1,CCOC(=O)C(=CNCCF)C(=O)c1cc(F)c(F)c(F)c1F>>CCOC(=O)c1cn(CCF)c2c(F)c(F)c(F)cc2c1=O -US20030060624A1,7,O=C1NCC2CC1c1ccccc12>>c1ccc2c(c1)C1CNCC2C1 -US20150191452A1,7,COc1ccc(C2=CCNCC2)cc1>>COc1ccc(C2CCNCC2)cc1 -US05602161,6,COc1ccc(-c2nnn(-c3ccc(C(C)C)cc3)n2)cc1>>CC(C)c1ccc(-n2nnc(-c3ccc(O)cc3)n2)cc1 -US20150056164A1,3,CC1(C)OB(c2ccc(F)cc2F)OC1(C)C.COc1c(Br)cc(I)cc1C(C)(C)C>>COc1c(Br)cc(-c2ccc(F)cc2F)cc1C(C)(C)C -US20100069367A1,4,CCOC(=O)C(=O)CC(C)=O.NNc1c(Cl)cccc1Cl>>CCOC(=O)c1cc(C)n(-c2c(Cl)cccc2Cl)n1 -US20140113944A1,6,CC(C)(C)OC(=O)N[C@@]1(C(=O)OCOC(=O)C(C)(C)C)C[C@H](Sc2nc[nH]n2)[C@H]2[C@H](C(=O)OCOC(=O)C(C)(C)C)[C@H]21>>CC(C)(C)C(=O)OCOC(=O)[C@H]1[C@@H]2[C@@H](Sc3nc[nH]n3)C[C@@](N)(C(=O)OCOC(=O)C(C)(C)C)[C@H]12 -US09073929B2,3,IC1COC1.OB(O)c1cncc(Br)c1>>Brc1cncc(C2COC2)c1 -US20040147612A1,7,CC(CNS(=O)(=O)C(C)C)c1ccc2cc(OCC#N)ccc2c1>>CC(CNS(=O)(=O)C(C)C)c1ccc2cc(OCCN)ccc2c1 -US05616601,9,Cc1cncc(C(N)=O)c1>>Cc1cncc(C#N)c1 -US05508385,6,CCCCOC(OCCCC)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H]1CCC(=O)N1C(=O)OCc1ccccc1>>C[C@H](NC(=O)[C@H]1CCC(=O)N1C(=O)OCc1ccccc1)C(=O)N[C@H](C=O)CCCNC(=N)N -US20060264415A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1ccc(I)cc1>>CC(C)(C)OC(=O)NCc1ccc(I)cc1 -US20070213331A1,6,CCCN(C)C(=O)c1cc(C(=O)OC)cc(C(=O)c2ccco2)c1>>CCCN(C)C(=O)c1cc(C(=O)O)cc(C(=O)c2ccco2)c1 -US20090082434A1,2,NCC1Cc2cc(F)cc(-c3ccccc3Cl)c2O1.O=C(Cl)OCc1ccccc1>>O=C(NCC1Cc2cc(F)cc(-c3ccccc3Cl)c2O1)OCc1ccccc1 -US20040138462A1,1,O[C@@H](CCl)c1ccc(Cl)nc1>>Clc1ccc([C@@H]2CO2)cn1 -US20110313151A1,2,Cc1nc(-c2cccc(C(=O)O)c2)no1.N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1>>Cc1nc(-c2cccc(C(=O)N[C@@H]3CC[C@@H](CCN4CCN(c5nccc6c5CCO6)CC4)CC3)c2)no1 -US06350774B1,6,O=C(c1ccc(O[C@@H]2CCCC[C@H]2N2CCOC2=O)cc1)c1c(-c2ccc(OCCN3CCCC3)cc2)sc2cc(OCc3ccccc3)ccc12>>O=C(c1ccc(O[C@@H]2CCCC[C@H]2N2CCOC2=O)cc1)c1c(-c2ccc(OCCN3CCCC3)cc2)sc2cc(O)ccc12 -US09018382B2,7,CCC(C)c1cc(C)[nH]c(=O)c1C#N>>CCC(C)c1cc(C)[nH]c(=O)c1CN -US08901141B2,1,CCC(NC(C)=O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl.CI>>CCC(c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl)N(C)C(C)=O -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.Cc1ccn(-c2ccc(C(=O)O)cc2)n1>>Cc1ccn(-c2ccc(C(=O)N3C[C@@H](c4ccc(F)cc4)[C@H](N(C)C(=O)N(C)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)C3)cc2)n1 -US20150051395A1,2,COC(=O)c1ccc(N)cc1F.Cc1cc(C(=O)O)ccc1S(=O)(=O)Cl>>COC(=O)c1ccc(NS(=O)(=O)c2ccc(C(=O)O)cc2C)cc1F -US20070293521A1,7,COC(=O)c1cc(COc2ccc([N+](=O)[O-])cc2)co1>>COC(=O)c1cc(COc2ccc(N)cc2)co1 -US20060089371A1,1,COC(=O)[C@H](N)Cc1ccccn1.Clc1cc(Cl)ncn1>>COC(=O)[C@@H](Cc1ccccn1)Nc1cc(Cl)ncn1 -US20100160323A1,2,CN.O=C(Cl)c1cccc([N+](=O)[O-])c1>>CNC(=O)c1cccc([N+](=O)[O-])c1 -US20080255142A1,1,C1CNCCN1.N#Cc1ccc(F)cc1F>>N#Cc1ccc(N2CCNCC2)cc1F -US20050234081A1,1,COC(=O)c1cc(S(=O)(=O)c2cnc(Cl)c(Br)c2)c(SC)s1.NCc1ccc(C(F)(F)F)nc1>>COC(=O)c1cc(S(=O)(=O)c2cnc(NCc3ccc(C(F)(F)F)nc3)c(Br)c2)c(SC)s1 -US05025025,8,COC(=O)C(C)(C)CC(CCO)CCCCO[Si](C)(C)C(C)(C)C>>COC(=O)C(C)(C)CC(CC=O)CCCCO[Si](C)(C)C(C)(C)C -US04927926,6,O=C(O)c1cn(C2CC2)c2c(F)c(N3CC(CNC(=O)C(F)(F)F)C3)c(F)cc2c1=O>>NCC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 -US20060247250A1,6,COc1ccc(Cl)c(C(=O)Nc2cnc(Nc3cccnc3)nc2)c1>>O=C(Nc1cnc(Nc2cccnc2)nc1)c1cc(O)ccc1Cl -US05962469,6,COc1ccc2c(c1)C(C)(C)NC2=O>>CC1(C)NC(=O)c2ccc(O)cc21 -US07872021B2,7,COC(=O)CCOc1cccc(C#N)c1>>COC(=O)CCOc1cccc(CN)c1 -US20120197027A1,1,COCCN(C)CCO.COc1cc2c(Oc3ccc4[nH]c(C)c(C)c4c3)ncnc2cc1O>>COCCN(C)CCOc1cc2ncnc(Oc3ccc4[nH]c(C)c(C)c4c3)c2cc1OC -US20080200448A1,1,CC(C)(C)OC(=O)C1CCNCC1.CCOC(=O)c1cc(Cl)c(Cl)nc1CN1CCCC1=O>>CCOC(=O)c1cc(Cl)c(N2CCC(C(=O)OC(C)(C)C)CC2)nc1CN1CCCC1=O -US20150126498A1,1,CI.COc1ccc(Br)nc1NC(=O)OC(C)(C)C>>COc1ccc(Br)nc1N(C)C(=O)OC(C)(C)C -US08901156B2,2,NCCc1coc(-c2cccc(F)c2)n1.O=C(O)c1cncc(-c2noc(C(F)(F)F)n2)c1>>O=C(NCCc1coc(-c2cccc(F)c2)n1)c1cncc(-c2noc(C(F)(F)F)n2)c1 -US20120108583A1,6,COC(=O)c1cc2nc(Nc3c(Cl)cccc3Cl)[nH]c2c2nc(C)oc12>>Cc1nc2c(o1)c(C(=O)O)cc1nc(Nc3c(Cl)cccc3Cl)[nH]c12 -US04584293,1,CNC1CCc2cc(Cl)c(Cl)cc2C1.COc1cc2c(cc1OC)CC(=O)N(CCCCl)CC2>>COc1cc2c(cc1OC)CC(=O)N(CCCN(C)C1CCc3cc(Cl)c(Cl)cc3C1)CC2 -US05180831,1,NNC(=O)Nc1ccccc1.O=Cc1ncccc1O>>O=C(NN=Cc1ncccc1O)Nc1ccccc1 -US06867204B2,2,CC(C)(C)OC(=O)N1CCN(c2cccc3c2OCCN3)CC1.O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1>>CC(C)(C)OC(=O)N1CCN(c2cccc3c2OCCN3S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1 -US03966748,8,Cc1csc(C2=CCN(CCCC(O)c3ccc(F)cc3)CC2)n1>>Cc1csc(C2=CCN(CCCC(=O)c3ccc(F)cc3)CC2)n1 -US20030130340A1,1,CCCBr.Oc1ccc2c(-c3cccnc3)csc2c1>>CCCOc1ccc2c(-c3cccnc3)csc2c1 -US20060189591A1,6,COC(=O)c1nc(-c2ccc(OCc3ccccc3)cn2)n(-c2ccc(OC)nc2)n1>>COC(=O)c1nc(-c2ccc(O)cn2)n(-c2ccc(OC)nc2)n1 -US20090312349A1,7,CCOC(=O)C(C)=Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1>>CCOC(=O)C(C)Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1 -US05079244,3,CC1CCCC(C)N1N.O=CCOCc1ccccc1.[C-]#N>>CC1CCCC(C)N1NC(C#N)COCc1ccccc1 -US20020177594A1,2,CN.COC(=O)C(=O)CCCCCCSc1ccc2ccccc2c1>>CNC(=O)C(=O)CCCCCCSc1ccc2ccccc2c1 -US20060094768A1,6,COC(=O)CCc1ccc(OCC(C)c2sc(-c3ccc(C(F)(F)F)cc3)cc2C)cc1C>>Cc1cc(OCC(C)c2sc(-c3ccc(C(F)(F)F)cc3)cc2C)ccc1CCC(=O)O -US20080027049A1,2,CCOC(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCC3>>CCOC(=O)Nc1ccc2oc3c(c2c1)CCCCC3 -US20070249670A1,2,COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1N)C1CCCCC1.Cc1cccc(C)c1N=C=O>>COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1NC(=O)Nc1c(C)cccc1C)C1CCCCC1 -US20110003787A1,2,COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(C(=O)O)[nH]2)c1.C[C@H](O)CN>>COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(C(=O)NC[C@H](C)O)[nH]2)c1 -US07560463B2,5,CC(C)[Si](Oc1ccc(C=O)cc1F)(C(C)C)C(C)C.OCCO>>CC(C)[Si](Oc1ccc(C2OCCO2)cc1F)(C(C)C)C(C)C -US06432993B1,2,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)ccc1N.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)ccc1NC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1 -US06635638B2,7,O=C(c1ccc(-c2ccc([N+](=O)[O-])cc2)o1)N1Cc2c([nH]c3ccccc3c2=O)C1c1ccc2c(c1)OCO2>>Nc1ccc(-c2ccc(C(=O)N3Cc4c([nH]c5ccccc5c4=O)C3c3ccc4c(c3)OCO4)o2)cc1 -US20150087663A1,2,C[C@H](NC(=O)OC(C)(C)C)C(=O)O.Nc1cccc(F)c1C(=O)Nc1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1cccc(F)c1C(=O)Nc1ccccc1 -US20070123495A1,1,COC(=O)CBr.Oc1ccc2cc(-c3ccc(-c4ccccc4)n3-c3ccccc3)ccc2c1>>COC(=O)COc1ccc2cc(-c3ccc(-c4ccccc4)n3-c3ccccc3)ccc2c1 -US20090253687A1,7,COC(=O)/C=C/c1cc(-c2ccc3c(c2)NC(=O)CO3)n(-c2ccc(F)cc2)n1>>COC(=O)CCc1cc(-c2ccc3c(c2)NC(=O)CO3)n(-c2ccc(F)cc2)n1 -US20090170907A1,2,N#Cc1ccc(N(CC(=O)O)CC(F)(F)F)cc1C(F)(F)F.NNC(=O)c1ccccn1>>N#Cc1ccc(N(CC(=O)NNC(=O)c2ccccn2)CC(F)(F)F)cc1C(F)(F)F -US20100034827A1,7,O=C(OCc1ccnc(F)c1)c1ccccc1>>OCc1ccnc(F)c1 -US20150284408A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=Cc1cc([N+](=O)[O-])ccc1O>>CC(C)(C)OC(=O)N1CCC(NCc2cc([N+](=O)[O-])ccc2O)CC1 -US20110306606A1,7,O=[N+]([O-])c1ccc(-c2csc(C3CCCCC3)n2)cc1>>Nc1ccc(-c2csc(C3CCCCC3)n2)cc1 -US20040192728A1,6,CC(C)(C)OC(=O)N1CCc2cc(C(=O)Nc3cnc4ccccc4c3)ccc21>>O=C(Nc1cnc2ccccc2c1)c1ccc2c(c1)CCN2 -US20120316147A1,2,CC(C)CSc1cccc(C(=O)O)n1.CC(C)C[C@H](N)C(N)=O>>CC(C)CSc1cccc(C(=O)N[C@@H](CC(C)C)C(N)=O)n1 -US07608629B2,1,C[C@@H]1CN(Cc2ccccc2)CC[C@@H]1O.Fc1cccc(Br)c1>>C[C@@H]1CN(Cc2ccccc2)CC[C@@H]1Oc1cccc(Br)c1 -US20040192708A1,2,CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(N)cc3)nc21.O=S(=O)(Cl)C=Cc1ccccc1>>CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(NS(=O)(=O)C=Cc4ccccc4)cc3)nc21 -US05338856,2,Cc1cc(C2CNN=C2c2ccccc2)on1.O=C=Nc1ccc(OC(F)(F)F)cc1>>Cc1cc(C2CN(C(=O)Nc3ccc(OC(F)(F)F)cc3)N=C2c2ccccc2)on1 -US07622474B2,7,Cc1cc([N+](=O)[O-])ccc1NC(=O)c1ccccc1>>Cc1cc(N)ccc1NC(=O)c1ccccc1 -US20100298325A1,1,CN1CCN(c2cccc(N)c2)CC1.Fc1ccc(Oc2ccc(Cl)nc2)cc1F>>CN1CCN(c2cccc(Nc3ccc(Oc4ccc(F)c(F)c4)cn3)c2)CC1 -US20150152065A1,1,CC(N)c1ccccc1.O=[N+]([O-])c1ccc(Br)cc1F>>CC(Nc1cc(Br)ccc1[N+](=O)[O-])c1ccccc1 -US06303613B1,9,N#Cc1c(Cl)cncc1N=[N+]=[N-]>>N#Cc1c(N)cncc1Cl -US08524702B2,2,CC(C)(C)OC(=O)NC1=Nc2cc(Br)ccc2C=C(C(=O)O)C1.CCCNCCCF>>CCCN(CCCF)C(=O)C1=Cc2ccc(Br)cc2N=C(NC(=O)OC(C)(C)C)C1 -US20130040930A1,1,Cc1cnc(N2CCN(C(=O)c3ccc(Br)nc3)CC2)c(C)c1.O=C1CCCCN1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCCC4=O)nc3)CC2)c(C)c1 -US08268822B2,2,CC(C)(C)OC(=O)N1CCC(NCc2cc(-c3ccnc(Cl)n3)ccc2F)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(N(Cc2cc(-c3ccnc(Cl)n3)ccc2F)S(C)(=O)=O)CC1 -US04760163,10,Cc1cn(C)c(=O)n(-c2cc(C(=O)OC(C)C)c(Cl)cc2F)c1=O.O=C1CCC(=O)N1Br>>CC(C)OC(=O)c1cc(-n2c(=O)c(CBr)cn(C)c2=O)c(F)cc1Cl -US06235789B1,7,COc1ccc2c(c1)/C(=C/CNC(C)=O)CCC2>>COc1ccc2c(c1)C(CCNC(C)=O)CCC2 -US20080233127A1,1,Cc1ccc(C=O)s1.Oc1cncc(-c2nc(N3CCOCC3)c3ncn(C4CCNCC4)c3n2)c1>>Cc1ccc(CN2CCC(n3cnc4c(N5CCOCC5)nc(-c5cncc(O)c5)nc43)CC2)s1 -US07514582B2,2,NCCc1ccccn1.O=C(NCc1ccccc1-c1ccccc1C(=O)O)OCc1ccccc1>>O=C(NCc1ccccc1-c1ccccc1C(=O)NCCc1ccccn1)OCc1ccccc1 -US06825170B2,8,OC/C=C/c1ccc(-n2cccn2)nc1>>O=C/C=C/c1ccc(-n2cccn2)nc1 -US05416066,2,C=CC(=O)Cl.c1ccc2c(c1)CNCCS2>>C=CC(=O)N1CCSc2ccccc2C1 -US06713645B1,1,COC(=O)CBr.NC(=O)c1cccc2c1c1c(O)cccc1n2Cc1ccccn1>>COC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1ccccn1 -US05859051,1,BrCCCBr.CCCc1c(O)ccc2c1ccn2-c1ccc(Cl)cc1>>CCCc1c(OCCCBr)ccc2c1ccn2-c1ccc(Cl)cc1 -US20080221157A1,6,COC(=O)CCCCCCC1(C)OCCO1>>CC1(CCCCCCC(=O)O)OCCO1 -US06136810,1,CCN.CCc1ccc(C(=O)c2cccc(Cl)c2)c(Cl)n1>>CCNc1nc(CC)ccc1C(=O)c1cccc(Cl)c1 -US20070249674A1,1,CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c(NC=O)c1.Cc1cc(NC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(C)cc1C=O>>Cc1cc(NC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(C)cc1CNC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c(NC=O)c1 -US20080045506A1,1,CC(C)N1CCN(C(=O)[C@H]2CCNC2)CC1.FC(F)(F)c1ccc(Br)cn1>>CC(C)N1CCN(C(=O)[C@H]2CCN(c3ccc(C(F)(F)F)nc3)C2)CC1 -US20060161001A1,1,Cc1cc(F)nc(F)n1.c1ccc(-c2ccc3c(n2)NCCC3)cc1>>Cc1cc(N2CCCc3ccc(-c4ccccc4)nc32)nc(F)n1 -US08877780B2,2,CCCN=C=O.NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O>>CCCNC(=O)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O -US08304412B2,2,CO.O=C(O)[C@@H]1CC[C@H](O)CC1>>COC(=O)[C@@H]1CC[C@H](O)CC1 -US20040204449A1,7,COC(=O)C1CN=Cc2ccc(OC)cc21>>COC(=O)C1CNCc2ccc(OC)cc21 -US07053086B2,3,Cc1cc(C(=O)O)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2ccncc2)N1>>Cc1cc(C(=O)O)c(C=C2C(=O)Nc3cccc(-c4ccncc4)c32)[nH]1 -US08946260B2,9,Fc1ccc2scc(CBr)c2c1.[C-]#N>>N#CCc1csc2ccc(F)cc12 -US20070203184A1,9,O=C(Nc1ccc(Cl)cc1)C(O)c1ccc(F)cc1Cl>>O=C(Nc1ccc(Cl)cc1)C(O)c1ccccc1Cl -US20120302641A1,3,COC(=O)c1ccc(B(O)O)cc1.COc1cc(C(F)(F)F)cc(Cl)c1C=O>>COC(=O)c1ccc(-c2cc(C(F)(F)F)cc(OC)c2C=O)cc1 -US20020004494A1,6,CCOC(CCN1CCCNC1=O)OCC>>O=CCCN1CCCNC1=O -US20080306082A1,1,Cc1cnc(NCCCC2CCNCC2)nc1-c1cc2c(C(=O)NC3CC3)cccc2s1.FCCBr>>Cc1cnc(NCCCC2CCN(CCF)CC2)nc1-c1cc2c(C(=O)NC3CC3)cccc2s1 -US20140371459A1,1,CC1=CC(C)(C)Nc2ccc3c(c21)c(=O)oc1cc(O)ccc13.ClCOCc1ccccc1>>CC1=CC(C)(C)Nc2ccc3c(c21)c(=O)oc1cc(OCOCc2ccccc2)ccc13 -US04940710,1,C1CCNC1.CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(F)c(F)c21>>CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCCC3)c(F)c21 -US08476298B2,2,Nc1ccc(F)cc1.O=C(O)C1(C(=O)O)CCC1>>O=C(O)C1(C(=O)Nc2ccc(F)cc2)CCC1 -US20110077243A1,3,Brc1cc(-c2ccccc2)c2nncn2c1.CCCC[Sn](/C=C\OCC)(CCCC)CCCC>>CCO/C=C\c1cc(-c2ccccc2)c2nncn2c1 -US20110009619A1,2,COc1nc(/C=C/C(=O)O)ccc1-n1cnc(C)c1.NN1CCCN(c2ccc(Cl)cc2)C1=O>>COc1nc(/C=C/C(=O)NN2CCCN(c3ccc(Cl)cc3)C2=O)ccc1-n1cnc(C)c1 -US07402672B2,6,CC(C)(C)OC(=O)n1c(C=O)cc2cnccc21>>O=Cc1cc2cnccc2[nH]1 -US20080021026A1,1,COc1cccc(S)c1.Cc1c(-c2ccnc(N)n2)sc2ccc(Br)cc12>>COc1cccc(Sc2ccc3sc(-c4ccnc(N)n4)c(C)c3c2)c1 -US08293768B2,2,Cc1nc(N2CCN(Cc3ccc(OC(F)(F)F)cc3)C2=O)sc1C(=O)O.NC[C@H](O)c1ccccc1>>Cc1nc(N2CCN(Cc3ccc(OC(F)(F)F)cc3)C2=O)sc1C(=O)NC[C@H](O)c1ccccc1 -US20060089382A1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Nc1c(Cl)cc(I)c2c1OCO2>>COc1cc2ncc(C#N)c(Nc3c(Cl)cc(I)c4c3OCO4)c2cc1OC -US06127403,2,CC(C)(C)C(=O)Cl.CCCCCCN1CCc2c1cc(C)c(N)c2C>>CCCCCCN1CCc2c1cc(C)c(NC(=O)C(C)(C)C)c2C -US05077409,7,Cc1nccn1-c1ccc([N+](=O)[O-])cc1>>Cc1nccn1-c1ccc(N)cc1 -US20070078156A1,2,CN1C(=O)Cc2c(N)cccc21.O=C=NCc1ccc(C(F)(F)F)cc1>>CN1C(=O)Cc2c(NC(=O)NCc3ccc(C(F)(F)F)cc3)cccc21 -US04389409,1,CCCCS.Clc1ccc(CC(Cl)n2ccnc2)c(Cl)c1>>CCCCSC(Cc1ccc(Cl)cc1Cl)n1ccnc1 -US20130203756A1,9,CC(C)(C)OC(=O)NCC=CB(O)O.CC(C)(O)C(C)(C)O>>CC(C)(C)OC(=O)NCC=CB1OC(C)(C)C(C)(C)O1 -US20110288066A1,6,CCCS(=O)(=O)c1cccc(C#Cc2cc(-c3cccs3)ccc2OCC(=O)OC(C)(C)C)c1>>CCCS(=O)(=O)c1cccc(C#Cc2cc(-c3cccs3)ccc2OCC(=O)O)c1 -US20150166480A1,6,CCC(F)CN1CCC(COc2ccc(-c3ccc(C(=O)OC)cc3)cc2)CC1>>CCC(F)CN1CCC(COc2ccc(-c3ccc(C(=O)O)cc3)cc2)CC1 -US20150105366A1,1,C[O-].Clc1nc2ccc(Br)cc2c(Cl)c1Cc1cc2ccccc2s1>>COc1nc2ccc(Br)cc2c(Cl)c1Cc1cc2ccccc2s1 -US20090298878A1,1,CNC.O=S(=O)(c1ccc(Cl)nc1)N1CCC(=NOCc2cccc(C(F)(F)F)c2)CC1>>CN(C)c1ccc(S(=O)(=O)N2CCC(=NOCc3cccc(C(F)(F)F)c3)CC2)cn1 -US20080051418A1,7,CCOC(=O)CCc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1OCC(C)C>>CC(C)COc1cc(Oc2ccc(C(F)(F)F)cn2)ccc1CCCO -US05866565,2,CN(C)C(=O)Cl.Oc1cnccc1N=CN1CCCC1>>CN(C)C(=O)Oc1cnccc1N=CN1CCCC1 -US20040192693A1,1,CC(C)Oc1ccc(NC(=O)Nc2ccc(F)c([N+](=O)[O-])c2)cc1.CCN1CCCC1CN>>CCN1CCCC1CNc1ccc(NC(=O)Nc2ccc(OC(C)C)cc2)cc1[N+](=O)[O-] -US20140323435A1,1,CN(C)CCO.Clc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3>>CN(C)CCOc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 -US20100308754A1,6,CC(=O)Nc1ccc(C=Cc2ccc(C=Cc3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1>>Nc1ccc(C=Cc2ccc(C=Cc3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1 -US05124478,3,CCOC(=O)CCc1ccc(OC)cc1OC.COc1ccc(C(=O)Cl)cc1>>CCOC(=O)CCc1cc(C(=O)c2ccc(OC)cc2)c(OC)cc1OC -US05449812,7,COC(=O)c1ccc([N+](=O)[O-])cc1S(=O)(=O)NC(C)(C)C>>COC(=O)c1ccc(N)cc1S(=O)(=O)NC(C)(C)C -US20020035137A1,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)O.CCCCCN>>CCCCCNC(=O)C(Cc1ccc([N+](=O)[O-])cc1)NC(=O)OC(C)(C)C -US20130338134A1,7,COc1cc(OC)c(F)c(/N=C/c2cnc3[nH]ccc3c2Cl)c1F>>COc1cc(OC)c(F)c(NCc2cnc3[nH]ccc3c2Cl)c1F -US05204086,1,CC(=O)Nc1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I.COCC(O)CCl>>COCC(O)CN(C(C)=O)c1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I -US08088760B2,7,NC(=O)c1cccc2nc(-c3ccc(-c4ccccn4)cc3)oc12>>NC(=O)c1cccc2nc(-c3ccc(C4CCCCN4)cc3)oc12 -US05872115,6,Brc1ccc2c(c1)C(N1CCC3(CC1)OCCO3)c1ccccc1CO2>>O=C1CCN(C2c3ccccc3COc3ccc(Br)cc32)CC1 -US09067905B2,3,COC(=O)c1c(CS(=O)(=O)c2ccccc2OC)ccc(Br)c1O.OB(O)c1ccoc1>>COC(=O)c1c(CS(=O)(=O)c2ccccc2OC)ccc(-c2ccoc2)c1O -US08815919B2,6,COC(=O)c1ccc(-c2ccccc2C)c(CN(C)C)c1>>Cc1ccccc1-c1ccc(C(=O)O)cc1CN(C)C -US05164392,1,NCc1ccccc1.O=C(O)c1c(F)cc(F)c(F)c1F>>O=C(O)c1c(F)cc(F)c(F)c1NCc1ccccc1 -US08815891B2,7,COCn1c(=O)c2cccnc2c2cc(CCCN(C)C)ccc21>>COCn1c(=O)c2c(c3cc(CCCN(C)C)ccc31)NCCC2 -US20020169313A1,1,N#Cc1ccc2c(c1)CN(S(=O)(=O)c1cccs1)[C@H](Cc1ccccc1)CN2.O=Cc1c[nH]cn1>>N#Cc1ccc2c(c1)CN(S(=O)(=O)c1cccs1)[C@H](Cc1ccccc1)CN2Cc1c[nH]cn1 -US20120202783A1,1,Cc1ccnc(Cl)n1.O=C(c1ccccc1-c1ccccc1)N1CC2CNC2C1>>Cc1ccnc(N2CC3CN(C(=O)c4ccccc4-c4ccccc4)CC32)n1 -US08067407B2,1,FC1(F)CNC1.O=c1c(-n2ccnn2)c[nH]n1-c1cc(Cl)ncn1>>O=c1c(-n2ccnn2)c[nH]n1-c1cc(N2CC(F)(F)C2)ncn1 -US08809371B2,6,Cn1cccc1-c1cncc(NC(=O)OC(C)(C)C)c1>>Cn1cccc1-c1cncc(N)c1 -US20130005702A1,3,CC1(C)OB(c2cn[nH]c2)OC1(C)C.Clc1ccc(C(CCn2ccnc2)c2ccc(Br)cc2)cc1>>Clc1ccc(C(CCn2ccnc2)c2ccc(-c3cn[nH]c3)cc2)cc1 -US07666888B2,2,COc1ccc(-c2oncc2C(=O)O)cc1.c1ccc(C2CCNC2)cc1>>COc1ccc(-c2oncc2C(=O)N2CCC(c3ccccc3)C2)cc1 -US08486953B2,1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(F)cc1O>>CC(C)(C)OC(=O)N1CCC(Oc2cc(F)ccc2[N+](=O)[O-])CC1 -US20130065911A1,2,COc1cncc(C(=O)O)c1.Nc1cnc(OCC(F)(F)F)c(C2CCCC2)c1>>COc1cncc(C(=O)Nc2cnc(OCC(F)(F)F)c(C3CCCC3)c2)c1 -US20100105917A1,2,N[C@@H]1CCCN(C(=O)c2ccc(Cl)cc2)C1.O=C(Cl)c1ccccc1>>O=C(N[C@@H]1CCCN(C(=O)c2ccc(Cl)cc2)C1)c1ccccc1 -US04499100,1,Cc1cccc(C)c1NC(=O)CCl.O=C1CCNCC1>>Cc1cccc(C)c1NC(=O)CN1CCC(=O)CC1 -US20150191478A1,6,CCOC(OCC)c1cc2cncc(-c3cc(CN4CCCC4)ccc3OC)c2o1>>COc1ccc(CN2CCCC2)cc1-c1cncc2cc(C=O)oc12 -US20060178370A1,1,CC(C)(C)OC(=O)NCC=O.N[C@@H](CC(=O)OCc1ccccc1)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCCN[C@H](CC(=O)OCc1ccccc1)C(=O)OCc1ccccc1 -US20090253687A1,4,Cc1cc(C(=O)CC(=O)C(C)(F)F)cc2c1OCC(=O)N2.Cc1cc(F)ccc1NN>>Cc1cc(F)ccc1-n1nc(C(C)(F)F)cc1-c1cc(C)c2c(c1)NC(=O)CO2 -US20110269712A1,8,Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C(=O)N(C)[C@@H]3CC[C@H](O)c4ccccc43)cs2)CC1>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C(=O)N(C)C3CCC(=O)c4ccccc43)cs2)CC1 -US20090286778A1,2,O=C(C[C@@H]1CCNC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2.O=C=Nc1ccccc1F>>O=C(C[C@@H]1CCN(C(=O)Nc2ccccc2F)C1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2 -US07115611B2,7,COCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1C(=O)OC>>COCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1CO -US09102591B2,2,Cc1ncc(C(CN)c2ccncc2)cn1.O=C(O)c1cccc(F)c1Cl>>Cc1ncc(C(CNC(=O)c2cccc(F)c2Cl)c2ccncc2)cn1 -US06294566B1,7,CC(=O)c1cc(-c2ccccc2)nc2ccccc12>>CC(O)c1cc(-c2ccccc2)nc2ccccc12 -US20100222317A1,2,C=C1CC(CN)(CC2CC2)C1.O=C(Cl)c1ccc(Cl)cc1Cl>>C=C1CC(CNC(=O)c2ccc(Cl)cc2Cl)(CC2CC2)C1 -US04965286,1,CC(C)COC(=O)CBr.CCCCN>>CCCCNCC(=O)OCC(C)C -US08431695B2,2,CS(=O)(=O)Cl.Nc1ncnn2c(C3CCNCC3)cc(-c3ccc4cn(-c5ccccc5)nc4c3)c12>>CS(=O)(=O)N1CCC(c2cc(-c3ccc4cn(-c5ccccc5)nc4c3)c3c(N)ncnn23)CC1 -US07410987B2,1,COc1ccc(O)c(C2Sc3cc(Cl)ccc3N2C(C)=O)c1.Cc1ccc(S(=O)(=O)OCCC(C)O)cc1>>COc1ccc(OC(C)CCOS(=O)(=O)c2ccc(C)cc2)c(C2Sc3cc(Cl)ccc3N2C(C)=O)c1 -US20040138248A1,1,BrCCCOCc1ccccc1.CCOCc1nc2cnc3ccccc3c2n1CCO>>CCOCc1nc2cnc3ccccc3c2n1CCOCCCOCc1ccccc1 -US20130267510A1,7,CC1(C)COc2cccc(Oc3ncc([N+](=O)[O-])cn3)c21>>CC1(C)COc2cccc(Oc3ncc(N)cn3)c21 -US20070066641A1,3,CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(Br)cnc21.O=C(Cl)OCc1ccccc1>>CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(C(=O)OCc3ccccc3)cnc21 -US20110207147A1,4,COc1ccc2c(c1)C(=O)CC2.NNc1ccccc1>>COc1ccc2c(c1)-c1[nH]c3ccccc3c1C2 -US04117128,6,COc1ccc(S(=O)(=O)c2c(Cc3ccccc3)oc3ccc(Br)cc23)cc1>>O=S(=O)(c1ccc(O)cc1)c1c(Cc2ccccc2)oc2ccc(Br)cc12 -US20090118305A1,2,CC(C)(C)OC(=O)N1C[C@H](n2cc(-c3cnc(N)c(-c4nc5ccccc5o4)c3)cn2)C[C@H]1C(=O)O.CN>>CNC(=O)[C@@H]1C[C@@H](n2cc(-c3cnc(N)c(-c4nc5ccccc5o4)c3)cn2)CN1C(=O)OC(C)(C)C -US08901141B2,1,NCCO.O=[N+]([O-])c1cccc([N+](=O)[O-])c1Cl>>O=[N+]([O-])c1cccc([N+](=O)[O-])c1NCCO -US09073864B2,3,COC(=O)c1ccc(NC(CCC(F)(F)F)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2C)cc1.FC(F)(F)c1cnc(Cl)nc1>>COC(=O)c1ccc(NC(CCC(F)(F)F)c2ccc(-c3ncc(C(F)(F)F)cn3)cc2C)cc1 -US05371239,1,CCI.N#Cc1c(Br)[nH]c(Br)c1Br>>CCn1c(Br)c(Br)c(C#N)c1Br -US07964591B2,2,CC(C)CCNC(=O)c1ccc(N2CCNCC2)nn1.O=C(O)c1cc(Cl)ccc1Cl>>CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3cc(Cl)ccc3Cl)CC2)nn1 -US08362048B2,6,CC(=O)OCCN([C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21)S(C)(=O)=O>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N(CCO)S(C)(=O)=O)no2)cc1C#N -US20120149721A1,2,CCC(=O)Cl.COc1ccc(-c2ncnc3c(C(=O)N[C@@H]4CCNC4)c(C)[nH]c23)c(OCC2CC2)c1>>CCC(=O)N1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4ccc(OC)cc4OCC4CC4)ncnc23)C1 -US20080194585A1,3,CC(C)Cn1c(-c2c(F)cccc2F)c(Cl)nc(Cl)c1=O.CCCC[Sn](CCCC)(CCCC)c1ccccn1>>CC(C)Cn1c(-c2c(F)cccc2F)c(Cl)nc(-c2ccccn2)c1=O -US20130072495A1,3,CC(C)(C)OC(=O)N1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.Clc1cc2cc[nH]c2nn1>>CC(C)(C)OC(=O)N1CCC(n2cc(-c3cc4cc[nH]c4nn3)cn2)CC1 -US20080255232A1,1,COc1ccc2ccccc2c1Br.COc1ccc2ccccc2c1N>>COc1ccc2ccccc2c1Nc1c(OC)ccc2ccccc12 -US20150152108A1,1,OCC[C@H]1CNc2ccc(Br)cc2N1>>Brc1ccc2c(c1)N[C@H]1CCN2C1 -US20100216746A1,2,Cc1n[nH]nc1C(=O)O.N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1>>Cc1n[nH]nc1C(=O)NCc1ccc(Cl)c(Oc2cc(Cl)cc(C#N)c2)c1F -US20140187779A1,2,COC(=O)Cc1c(N(C)C)nc(Cc2ccc(N)cc2)nc1N(C)C.O=C(O)c1ccc(C(F)(F)F)cc1>>COC(=O)Cc1c(N(C)C)nc(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)nc1N(C)C -US20100179137A1,2,CCOC(=O)CN.CCc1cccc(OCc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)O)cc2)c1>>CCOC(=O)CNC(=O)c1ccc(CCn2c(COc3cccc(CC)c3)c(Cl)cc(Cl)c2=O)cc1 -US20050143429A1,2,CC(C)OC(OC(C)C)C(C)(C)C(=O)C(C)C(O)C(C)COCc1ccccc1.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)OC(OC(C)C)C(C)(C)C(=O)C(C)C(OC(=O)OCC(Cl)(Cl)Cl)C(C)COCc1ccccc1 -US20120245136A1,2,COc1ccccc1C(=O)O.O=C1CC2(CCNCC2)Oc2ccccc21>>COc1ccccc1C(=O)N1CCC2(CC1)CC(=O)c1ccccc1O2 -US05789423,6,COc1ccc(C(C)C#N)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1>>COc1ccc(C(C)C#N)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 -US20120172333A1,3,O=c1[nH]c2ccn(-c3ccc(Br)cc3)c2c(O)c1-c1ccccc1.OB(O)c1ccccc1O>>O=c1[nH]c2ccn(-c3ccc(-c4ccccc4O)cc3)c2c(O)c1-c1ccccc1 -US20140371201A1,3,COc1cc(Br)c(Cl)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21.OB(O)c1cccc(F)c1>>COc1cc(-c2cccc(F)c2)c(Cl)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21 -US20080214622A1,1,CI.O=C(O)c1ccc(Br)cc1O>>COc1cc(Br)ccc1C(=O)O -US08809363B2,9,CC(C)(O)C(C)(C)O.OB(O)c1ccc(Cl)cc1O>>CC1(C)OB(c2ccc(Cl)cc2O)OC1(C)C -US20150021590A1,1,CCNc1ncccc1N.Ic1ccccc1>>CCNc1ncccc1Nc1ccccc1 -US20090233929A1,3,CON(C)C(=O)c1cn(-c2cccc(-c3cccnc3F)c2)cn1.Fc1ccc(Br)cc1>>O=C(c1ccc(F)cc1)c1cn(-c2cccc(-c3cccnc3F)c2)cn1 -US20040106623A1,1,C[C@@H](CCl)N1C(=O)CC2(CCCC2)CC1=O.Fc1ccc(F)c(N2CCNCC2)c1>>C[C@@H](CN1CCN(c2cc(F)ccc2F)CC1)N1C(=O)CC2(CCCC2)CC1=O -US08685992B2,2,COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)O)cc1.NCc1ccc(C(=O)Nc2ccccn2)cc1>>COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)NCc2ccc(C(=O)Nc3ccccn3)cc2)cc1 -US06589977B1,7,Cc1ccc2[nH]cc(C3=C(c4c[nH]c5ccc(C)cc45)C(=O)N(C)C3=O)c2c1>>Cc1ccc2[nH]cc(C3C(=O)N(C)C(=O)C3c3c[nH]c4ccc(C)cc34)c2c1 -US05554750,2,CCOC(=O)CCC(N)c1cccc(OC)c1>>COc1cccc(C2CCC(=O)N2)c1 -US20070129416A1,2,CCOc1cc(C(C)C)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCCN1CCNCC1>>CCOc1cc(C(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1 -US20040236084A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc(C#N)c(NC4CCCC4)n3)nc2)CC1>>N#Cc1cnc(Nc2ccc(N3CCNCC3)cn2)nc1NC1CCCC1 -US07635698B2,2,CC(C)(C)OC(=O)NCCNC1CN(C(=O)c2ccc(Cl)cc2)CC1O[Si](C)(C)C(C)(C)C.O=C(Cl)CCl>>CC(C)(C)OC(=O)NCCN(C(=O)CCl)C1CN(C(=O)c2ccc(Cl)cc2)CC1O[Si](C)(C)C(C)(C)C -US04769472,1,COc1ccc(C(=NN)c2sccc2Br)cc1>>COc1ccc(-c2n[nH]c3ccsc23)cc1 -US05217969,1,CN1C(=O)COc2cc(Br)cnc21.COC1(c2cc(F)cc(S)c2)CCOCC1>>COC1(c2cc(F)cc(Sc3cnc4c(c3)OCC(=O)N4C)c2)CCOCC1 -US20130116241A1,3,BrC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc2cc(F)ccc2n1>>Fc1ccc2nc(/C=C\Br)ccc2c1 -US20100280049A1,2,CC(C)(C)OC(=O)N1CCCC(C(=O)O)C1.Nc1ccccc1Br>>CC(C)(C)OC(=O)N1CCCC(C(=O)Nc2ccccc2Br)C1 -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1NC(=O)Nc1c(C)cccc1C)C1CCCCC1>>Cc1cccc(C)c1NC(=O)Nc1cc(Cl)ccc1C(=O)N[C@H](C(=O)O)C1CCCCC1 -US05571810,7,CSc1ccc(-c2cc(C(=O)N(C)C)sc2-c2ccc(F)cc2)cc1>>CSc1ccc(-c2cc(CN(C)C)sc2-c2ccc(F)cc2)cc1 -US20060167009A1,2,CS(=O)(=O)c1ccc(OCC2CCC2)c(C(=O)O)c1.N#Cc1cnc(N2CCNCC2)s1>>CS(=O)(=O)c1ccc(OCC2CCC2)c(C(=O)N2CCN(c3ncc(C#N)s3)CC2)c1 -US20060189549A1,2,CC(C)CN=C=S.COc1ccc(C(=O)NN)c(OC)c1>>COc1ccc(C(=O)NNC(=S)NCC(C)C)c(OC)c1 -US04634705,2,C=CCc1cccc2c1NCC2.CCOC(=O)Cl>>C=CCc1cccc2c1N(C(=O)OCC)CC2 -US04246267,2,CCC(=O)N(c1ccccc1)C1CCN(CCNc2c(C)cccc2C)CC1.CCCC(=O)Cl>>CCCC(=O)N(CCN1CCC(N(C(=O)CC)c2ccccc2)CC1)c1c(C)cccc1C -US20090054435A1,1,C=CCOC(=O)[C@H](C)O.COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O)c1>>C=CCOC(=O)[C@@H](C)Oc1cc(OC)ccc1C(=O)c1ccc(OCc2nc(-c3ccccc3)oc2C)cc1 -US20140296068A1,1,C#CCBr.Cc1nc(-c2cccnc2)cn1NC(=O)OC(C)(C)C>>C#CCN(C(=O)OC(C)(C)C)n1cc(-c2cccnc2)nc1C -US20150065464A1,6,C(=C1CCC2(CC1)OCCO2)c1cccc(Oc2ccc(C3CC3)cn2)c1>>O=C1CCC(=Cc2cccc(Oc3ccc(C4CC4)cn3)c2)CC1 -US08097733B2,8,C[C@H]1C[C@@](C#N)(c2cccc(Sc3ccc(-c4ccnn4C)cc3)c2F)CCO1.OO>>C[C@H]1C[C@@](C#N)(c2cccc(S(=O)c3ccc(-c4ccnn4C)cc3)c2F)CCO1 -US07265128B2,4,NC(=S)c1ccc(C(F)(F)F)cc1.O=C1CCNCC1Br>>FC(F)(F)c1ccc(-c2nc3c(s2)CNCC3)cc1 -US08367708B2,2,CO.O=C(O)c1cccnc1O>>COC(=O)c1cccnc1O -US20140194408A1,1,CC(O)Cn1nc([N+](=O)[O-])cc1CBr.CN>>CNCc1cc([N+](=O)[O-])nn1CC(C)O -US05374625,7,CC(C)(C)C(O[SiH](c1ccccc1)c1ccccc1)[C@H]1CCC(=O)[C@@H]1C(O[SiH](c1ccccc1)c1ccccc1)C(C)(C)C>>CC(C)(C)C(O[SiH](c1ccccc1)c1ccccc1)[C@H]1CC[C@H](O)[C@H]1C(O[SiH](c1ccccc1)c1ccccc1)C(C)(C)C -US06281357B1,2,CNC(C)(C)C.COC(=O)CS(=O)(=O)Cl>>COC(=O)CS(=O)(=O)N(C)C(C)(C)C -US04734367,7,CCOC(=O)C(C=O)Cc1ccccc1>>CCOC(=O)[C@@H](CO)Cc1ccccc1 -US20080280882A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(CN2CC3CCC(C2)N3)cc1>>CC(C)(C)OC(=O)N1C2CCC1CN(Cc1ccccc1)C2 -US20130040930A1,1,C[C@H]1CNS(=O)(=O)C1.Cc1ccc(N2CCN(C(=O)c3ccc(Br)nc3)CC2)c(C)c1>>Cc1ccc(N2CCN(C(=O)c3ccc(N4C[C@H](C)CS4(=O)=O)nc3)CC2)c(C)c1 -US20150210688A1,6,COC(=O)c1cc(-c2[nH]c(C3CC3)nc2C)c(C)cc1C>>Cc1cc(C)c(-c2[nH]c(C3CC3)nc2C)cc1C(=O)O -US07528256B2,3,O=C(O)c1cncc(Br)c1.OB(O)c1ccc(F)cc1>>O=C(O)c1cncc(-c2ccc(F)cc2)c1 -US08232273B2,1,CN1CCC(=O)CC1.Nc1ccc(O)cc1>>CN1CCC(Nc2ccc(O)cc2)CC1 -US08637670B2,2,CC(C)(C#N)c1ccc(-n2c(=O)[nH]c3cnc4ccc(Br)cc4c32)cc1.O=S(=O)(Cl)c1cc(F)cc(F)c1>>CC(C)(C#N)c1ccc(-n2c(=O)n(S(=O)(=O)c3cc(F)cc(F)c3)c3cnc4ccc(Br)cc4c32)cc1 -US20140288046A1,1,CC(C)(C)c1nc(N2CC(F)(F)C(F)(F)C2)c2nn[nH]c2n1.Cc1nnc(CCl)o1>>Cc1nnc(Cn2nnc3c(N4CC(F)(F)C(F)(F)C4)nc(C(C)(C)C)nc32)o1 -US20110021532A1,3,CS(=O)(=O)c1ccc2nc(-c3ccc(Br)cc3)[nH]c2c1.OB(O)c1ccsc1>>CS(=O)(=O)c1ccc2nc(-c3ccc(-c4ccsc4)cc3)[nH]c2c1 -US20040242884A1,1,CCOC(=O)c1c[nH]c2c(C)c(C=O)sc2c1=O.CI>>CCOC(=O)c1cn(C)c2c(C)c(C=O)sc2c1=O -US20140336198A1,3,CC(C)[Mg+].O=Cc1ccc(OC(F)F)cc1>>CC(C)C(O)c1ccc(OC(F)F)cc1 -US05561133,2,CNCC(=O)O.O=C(Cl)OCc1ccccc1>>CN(CC(=O)O)C(=O)OCc1ccccc1 -US07998975B2,1,CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3cccc(C#Cc4ccc(/C=C/CC(=O)NC(C)(C)C(=O)N5CCN(C(=O)OCc6ccccc6)CC5)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C.NC(=O)CBr>>CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2nn(CC(N)=O)c3cccc(C#Cc4ccc(/C=C/CC(=O)NC(C)(C)C(=O)N5CCN(C(=O)OCc6ccccc6)CC5)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C -US07235546B2,2,Cc1ccc2c(c1)c(N1CCNCC1)c(C#N)c(=O)n2C.O=C(Cl)c1cccs1>>Cc1ccc2c(c1)c(N1CCN(C(=O)c3cccs3)CC1)c(C#N)c(=O)n2C -US08981084B2,2,N#Cc1ccc(N2CCC(C(=O)O)C2)nc1.Nc1cccc(-c2noc(C(F)(F)F)n2)c1>>N#Cc1ccc(N2CCC(C(=O)Nc3cccc(-c4noc(C(F)(F)F)n4)c3)C2)nc1 -US05093353,1,BrCCCBr.Oc1ccc(Cl)c(Cl)c1>>Clc1ccc(OCCCBr)cc1Cl -US08476253B2,2,CNCCN(C)C(=O)OC(C)(C)C.Cc1cc(NC(=O)OC(C)(C)C)sc1C(=O)O>>Cc1cc(NC(=O)OC(C)(C)C)sc1C(=O)N(C)CCN(C)C(=O)OC(C)(C)C -US20020120139A1,1,BrCCCCCCCBr.Sc1ccc(Cl)cc1>>Clc1ccc(SCCCCCCCBr)cc1 -US20060014965A1,7,CCOC(=O)Cc1c(C)c2c(c([N+](=O)[O-])c1C)N(C(C)=O)CC2>>CCOC(=O)Cc1c(C)c(N)c2c(c1C)CCN2C(C)=O -US20150025073A1,6,COC(=O)c1ccc(S(C)(=O)=O)c(C)c1>>Cc1cc(C(=O)O)ccc1S(C)(=O)=O -US05925624,6,CC(C)(C)OC(=O)NC[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC[C@@H](N)Cc1ccccc1 -US04912105,1,CC(COS(C)(=O)=O)N1c2ccccc2Sc2ccc(C#N)cc21.CC1CCCN1>>CC1CCCN1CC(C)N1c2ccccc2Sc2ccc(C#N)cc21 -US20110263589A1,1,COc1ccccc1-c1ccc2c(c1CCl)C(C)=CC(C)(C)N2.OCc1ccccc1>>COc1ccccc1-c1ccc2c(c1COCc1ccccc1)C(C)=CC(C)(C)N2 -US07019022B2,3,C[Mg+].O=Cc1ccc(Cl)c(F)c1>>CC(O)c1ccc(Cl)c(F)c1 -US20070219181A1,2,CCOC(=O)C(C#N)(CCCCl)c1ccccc1.NN>>N#CC(CCCCl)(C(=O)NN)c1ccccc1 -US04526962,6,CC(=O)Nc1ncc(C2=C(C(=O)OC(c3ccccc3)c3ccccc3)N3C(=O)C(NC(=O)OC(C)(C)C)C3SC2)s1>>CC(=O)Nc1ncc(C2=C(C(=O)OC(c3ccccc3)c3ccccc3)N3C(=O)C(N)C3SC2)s1 -US07148234B2,1,CC(=O)c1cnc(Cl)c([N+](=O)[O-])c1.CC(O)Cc1ccc(N)cc1>>CC(=O)c1cnc(Nc2ccc(CC(C)O)cc2)c([N+](=O)[O-])c1 -US20060189549A1,6,COc1cc(OC)c(C2OCCO2)cc1-c1cnccn1>>COc1cc(OC)c(-c2cnccn2)cc1C=O -US20070254931A1,2,CC(=O)Cl.CCOC(=O)c1nc(N)sc1Cc1ccccc1>>CCOC(=O)c1nc(NC(C)=O)sc1Cc1ccccc1 -US04595535,7,Cc1nc(Cc2ccccc2[N+](=O)[O-])n[nH]1>>Cc1nc(Cc2ccccc2N)n[nH]1 -US20130072679A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Oc1cncc(Br)c1>>CC(C)(C)OC(=O)N1CCC(Oc2cncc(Br)c2)CC1 -US07517873B2,1,COCCNCCC(=O)OC(C)(C)C.O=[N+]([O-])c1cnc(Cl)nc1Cl>>COCCN(CCC(=O)OC(C)(C)C)c1nc(Cl)ncc1[N+](=O)[O-] -US20040048916A1,7,CC(C)CN1C(=O)c2ccc(Cl)cc2C1=O>>CC(C)CN1C(=O)c2ccc(Cl)cc2C1O -US05013737,7,CCOC(=O)c1cnn2c(-c3cccc(C(F)(F)F)c3)ccnc12>>CCOC(=O)c1cnn2c1NCC=C2c1cccc(C(F)(F)F)c1 -US20070122444A1,1,CCc1occc(=O)c1O.COc1ccc(Nc2nc(Cl)nc(NC3CCCCCC3)n2)cc1Cl>>CCc1occc(=O)c1Oc1nc(Nc2ccc(OC)c(Cl)c2)nc(NC2CCCCCC2)n1 -US04321268,1,O=C(O)c1cccnc1.O=C(c1ccccc1)c1cc(Cl)ccc1O>>O=C(Oc1ccc(Cl)cc1C(=O)c1ccccc1)c1cccnc1 -US08729271B2,2,Cn1cnc(C(=O)O)c1.Fc1ccc(CNC2CCC2)cc1Br>>Cn1cnc(C(=O)N(Cc2ccc(F)c(Br)c2)C2CCC2)c1 -US20080261941A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1cccc(Oc2ccc(C(F)(F)F)cc2)c1)OCC>>CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cc3)c2)CC1 -US07709647B2,2,NC1Cc2cc(Cl)ccc2N(Cc2ccccc2)C1.O=C(O)CCc1ccc2c(c1)OCO2>>O=C(CCc1ccc2c(c1)OCO2)NC1Cc2cc(Cl)ccc2N(Cc2ccccc2)C1 -US04857539,1,C[Sn](C)(C)Cl.c1ccoc1>>C[Sn](C)(C)c1ccco1 -US20090298812A1,7,N#CC1(N2CCN(C3CC3)CC2)CCN(Cc2ccccc2)CC1>>NCC1(N2CCN(C3CC3)CC2)CCN(Cc2ccccc2)CC1 -US20100331293A1,1,Cc1c(-c2ccccc2S(C)=O)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>Cc1c(-c2ccccc2S(C)=O)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1 -US20080015202A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(C=O)s1>>COC(=O)/C=C/c1ccc(C=O)s1 -US08987295B2,2,COC(=O)[C@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)CO3.COc1cc(C)ccc1S(=O)(=O)Cl>>COC(=O)[C@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1S(=O)(=O)c1ccc(C)cc1OC)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)CO3 -US05236952,6,COc1cc(-c2nc3ccccc3[nH]2)cc([N+](=O)[O-])c1O>>O=[N+]([O-])c1cc(-c2nc3ccccc3[nH]2)cc(O)c1O -US20070093548A1,3,N#Cc1ccc2oc3c(Br)c(O)c(F)cc3c2c1.OB(O)c1ccccc1F>>N#Cc1ccc2oc3c(-c4ccccc4F)c(O)c(F)cc3c2c1 -US20020173527A1,1,CC(C)=CCBr.COC(=O)c1ccc(N)c(I)c1>>COC(=O)c1ccc(NCC=C(C)C)c(I)c1 -US09067898B1,6,CCOC(=O)CCc1ccc(OC)c(C)c1C(F)(F)F>>CCOC(=O)CCc1ccc(O)c(C)c1C(F)(F)F -US20040142999A1,2,N#C[C@@H](N)CCc1ccccc1.O=C(O)C(F)(F)CCCc1ccccc1>>N#C[C@H](CCc1ccccc1)NC(=O)C(F)(F)CCCc1ccccc1 -US20100298287A1,2,CCO.O=C(O)C(F)(F)CNc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>CCOC(=O)C(F)(F)CNc1c([N+](=O)[O-])cccc1[N+](=O)[O-] -US20080255083A1,6,O=C(N1CCc2ccc(CCn3ccc(OCc4ccccc4)cc3=O)cc2CC1)C(F)(F)F>>O=c1cc(OCc2ccccc2)ccn1CCc1ccc2c(c1)CCNCC2 -US20080108598A1,2,CNC1CCCCC1.O=C(O)c1ccc2cc[nH]c2c1>>CN(C(=O)c1ccc2cc[nH]c2c1)C1CCCCC1 -US20110112140A1,3,COc1ccc(B(O)O)c(OC)n1.O=C(COCC(=O)Nc1ccc(Cl)cc1C(=O)O)Nc1cccc(Br)c1>>COc1ccc(-c2cccc(NC(=O)COCC(=O)Nc3ccc(Cl)cc3C(=O)O)c2)c(OC)n1 -US20100056801A1,3,C#CC(=C)C.C=CC(C)=O>>C=CC(C)(O)C#CC(=C)C -US20030064992A1,1,COC(=O)c1ccccc1N.O=Cc1ccncc1>>COC(=O)c1ccccc1NCc1ccncc1 -US20150218170A1,2,CC(C)(C)N.C[Si](C)(C)CCOCn1cc(C(=O)O)c2nc(Br)c(Cl)nc21>>CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2nc(Cl)c(Br)nc12 -US20150119405A1,1,COC(=O)[C@H]1C[C@@H](Nc2ncc3cc(-c4c(Cl)c(OC)cc(OC)c4Cl)ccc3n2)[C@H](O)C1.O=C1NC(=O)c2ccccc21>>COC(=O)C1C[C@@H](Nc2ncc3cc(-c4c(Cl)c(OC)cc(OC)c4Cl)ccc3n2)[C@@H](N2C(=O)c3ccccc3C2=O)C1 -US08394835B2,2,COC(=O)c1ccc(N)cc1.COc1cc(CCC(=O)O)cc(OC)c1OC>>COC(=O)c1ccc(NC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1 -US20070149570A1,3,O=Cc1cc(Br)ccc1OC(F)(F)F.OB(O)c1ccc(Cl)cc1Cl>>O=Cc1cc(-c2ccc(Cl)cc2Cl)ccc1OC(F)(F)F -US07427615B2,1,Cn1c(Cl)nc(-c2ccncc2)cc1=O.NCC(=O)c1ccccc1>>Cn1c(NCC(=O)c2ccccc2)nc(-c2ccncc2)cc1=O -US04009172,2,COC(=O)Cl.O=C(O)[C@@H]1CSC(c2ccccc2)N1>>COC(=O)N1C(c2ccccc2)SC[C@H]1C(=O)O -US20070255065A1,6,O=C1c2ccccc2C(=O)N1C[C@H]1COc2cc(F)cc(-c3c(Cl)cccc3Cl)c2O1>>NC[C@H]1COc2cc(F)cc(-c3c(Cl)cccc3Cl)c2O1 -US05627281,1,CC(C)(O)CN.O=[N+]([O-])c1c(OS(=O)(=O)C(F)(F)F)nc2c(c1OS(=O)(=O)C(F)(F)F)CCCC2>>CC(C)(O)CNc1c2c(nc(OS(=O)(=O)C(F)(F)F)c1[N+](=O)[O-])CCCC2 -US20020052322A1,2,C1CSCN1.C[C@H](NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H](C)C(=O)N1CCSC1 -US20050090559A1,1,COc1cccc(F)c1C(C)(C)CC(O)(C=O)C(F)(F)F.Cc1ncc2c(N)ccc(F)c2n1>>COc1cccc(F)c1C(C)(C)CC(O)(CNc1ccc(F)c2nc(C)ncc12)C(F)(F)F -US06083955,1,COc1ccccc1Oc1c(Cl)nc(-c2ncccn2)nc1NS(=O)(=O)C=Cc1cccc(C)c1.OCCO>>COc1ccccc1Oc1c(NS(=O)(=O)C=Cc2cccc(C)c2)nc(-c2ncccn2)nc1OCCO -US20080214607A1,1,OCc1cnc2ccccc2n1.Oc1ccc(-c2nn(CC(F)(F)F)cc2-c2ccncc2)cc1>>FC(F)(F)Cn1cc(-c2ccncc2)c(-c2ccc(OCc3cnc4ccccc4n3)cc2)n1 -US20030225276A1,3,CS(=O)(=O)c1ccc(-c2cnn(Cc3ccccc3)c(=O)c2Cl)cc1.OB(O)c1ccsc1>>CS(=O)(=O)c1ccc(-c2cnn(Cc3ccccc3)c(=O)c2-c2ccsc2)cc1 -US06599917B1,1,O=S(=O)(Oc1cc(Cc2ccccc2)c(Br)cn1)C(F)(F)F.O[C@@H]1CNC[C@H]1O>>O[C@@H]1CN(c2cc(Cc3ccccc3)c(Br)cn2)C[C@H]1O -US09073891B2,3,CCCC[Sn](CCCC)(CCCC)c1ncco1.O=[N+]([O-])c1ccsc1Cl>>O=[N+]([O-])c1ccsc1-c1ncco1 -US04478838,2,CCNC(=O)C(C)N1CCNCC1.COc1cc(C=CC(=O)Cl)cc(OC)c1OC>>CCNC(=O)C(C)N1CCN(C(=O)C=Cc2cc(OC)c(OC)c(OC)c2)CC1 -US05296496,2,COC(=O)C1=C(S(N)(=O)=O)CCCC1(C)C>>CC1(C)CCCC2=C1C(=O)NS2(=O)=O -US08327467B2,1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1N.CN(C)c1ccccc1Br>>CN(C)c1ccccc1Nc1cc(-c2ccccc2)ccc1C(=O)OC(C)(C)C -US20120329784A1,9,CNS(=O)(=O)c1cncc(Br)c1.[NH4+]>>CNS(=O)(=O)c1cncc(N)c1 -US20090137577A1,1,C[C@@H]1CN(Cc2ccc(OCC3CCC(=O)CC3)cc2)C(=O)O1.NC1CCC1>>C[C@@H]1CN(Cc2ccc(OCC3CCC(NC4CCC4)CC3)cc2)C(=O)O1 -US04097608,2,COc1ccc(C(=O)Cl)cc1.N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O>>COc1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)O)cc1 -US20100216788A1,1,CC(C)(C)OC(=O)N1CCC(Cn2ccc3cc(N)ccc32)CC1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>CC(C)(C)OC(=O)N1CCC(Cn2ccc3cc(Nc4ncnc5ccn(CCOC(=O)c6ccccc6)c45)ccc32)CC1 -US05952306,6,CCOC(=O)C[C@H](NC(=O)CNC(=O)OC(C)(C)C)c1cccnc1>>CCOC(=O)C[C@H](NC(=O)CN)c1cccnc1 -US20070254866A1,6,CCOC(=O)c1cn(C2CC2)c2c(OC(C)C)c(F)c(F)c(N)c2c1=O>>CC(C)Oc1c(F)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12 -US03941841,8,CC1=C(CO)C(C)(C)CC2(C1)OCCO2>>CC1=C(C=O)C(C)(C)CC2(C1)OCCO2 -US04012367,6,CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C)C(N)=O>>CSCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C)C(N)=O -US20150274705A1,6,C1CC2(CCC3(CC2)OCCO3)CN1>>O=C1CCC2(CCNC2)CC1 -US04772600,2,CNC.Cc1ccc(-c2nc3cccnc3n2CC(=O)O)s1>>Cc1ccc(-c2nc3cccnc3n2CC(=O)N(C)C)s1 -US20110059948A1,1,C[O-].Clc1nc2ccc(Br)cc2cc1Cc1ccccc1>>COc1nc2ccc(Br)cc2cc1Cc1ccccc1 -US20090306087A1,3,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Br)nc23)c1F.COc1ncc(B(O)O)cn1>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4cnc(OC)nc4)nc23)c1F -US20100056516A1,1,CC(=O)c1cnc2c(c1)c(O)c(-c1ccccc1)c(=O)n2OCc1ccccc1.NCc1cccc(Cl)c1>>CC(NCc1cccc(Cl)c1)c1cnc2c(c1)c(O)c(-c1ccccc1)c(=O)n2OCc1ccccc1 -US20060222601A1,2,CCOC(=O)c1ccc([N+](=O)[O-])cc1.NN>>NNC(=O)c1ccc([N+](=O)[O-])cc1 -US20040097563A1,7,CC(C)(C)[Si](C)(C)Oc1ccccc1-c1cc(-c2cccc([N+](=O)[O-])c2)c(C#N)c(N)n1>>CC(C)(C)[Si](C)(C)Oc1ccccc1-c1cc(-c2cccc(N)c2)c(C#N)c(N)n1 -US07115611B2,2,CCOC(=O)C(C)(C)Oc1ccc(CN)c(Cl)c1.O=C(O)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1C1CC1>>CCOC(=O)C(C)(C)Oc1ccc(CNC(=O)c2cnc(-c3ccc(C(F)(F)F)cc3)nc2C2CC2)c(Cl)c1 -US20040266822A1,2,CC(C)C(C)(C)N.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)NC(C)(C)C(C)C)cc1 -US08598161B2,1,CC(C)(C)OC(=O)NC1=N[C@]2(c3cc(N)ccc3F)OCC[C@@H]2CS1.O=C1CCCC1>>CC(C)(C)OC(=O)NC1=N[C@]2(c3cc(NC4CCCC4)ccc3F)OCC[C@@H]2CS1 -US07553867B2,3,COCOc1cccc(C=O)c1.C[Mg+]>>COCOc1cccc(C(C)O)c1 -US20130122042A1,1,CCOC(=O)CCc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(O)cc3C)cc12.CCOP(=O)(OCC)C(F)(F)CCCBr>>CCOC(=O)CCc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCCC(F)(F)P(=O)(OCC)OCC)cc3C)cc12 -US20130196974A1,1,Cc1ccc2nc(N3CCS(=O)(=O)c4cc(O)ccc4C3)cc(Cl)c2c1.Ic1ccccc1>>Cc1ccc2nc(N3CCS(=O)(=O)c4cc(Oc5ccccc5)ccc4C3)cc(Cl)c2c1 -US07220769B2,6,COC(=O)c1ccc(-c2nc3cc(Cl)c(Cl)cc3[nH]2)cc1>>O=C(O)c1ccc(-c2nc3cc(Cl)c(Cl)cc3[nH]2)cc1 -US20140364433A1,2,C[C@@H]1CCCN[C@@H]1CN1C(=O)c2ccccc2C1=O.Cc1nc(C(=O)O)c(-c2ccc(F)cc2)s1>>Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CN2C(=O)c3ccccc3C2=O)c(-c2ccc(F)cc2)s1 -US04252803,1,O=C(O)c1ccc2[nH]cc(CCN3C(=O)c4ccccc4C3=O)c2c1.O=[N+]([O-])c1ccc(O)cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)c1ccc2[nH]cc(CCN3C(=O)c4ccccc4C3=O)c2c1 -US07880007B2,3,C#Cc1ccccc1.COc1ccc(Br)cc1C1CCN([C@@H]2C[C@@H]3CC[C@H]2C3)CC1>>COc1ccc(C#Cc2ccccc2)cc1C1CCN([C@@H]2C[C@@H]3CC[C@H]2C3)CC1 -US20120190701A1,1,CI.COC(=O)c1cc(CCO)cc(C)c1C>>COCCc1cc(C)c(C)c(C(=O)OC)c1 -US09056914B2,6,CCOC(=O)c1cc(OCCNC(=O)OC(C)(C)C)cc(C(=O)OCC)n1>>CCOC(=O)c1cc(OCCN)cc(C(=O)OCC)n1 -US05344845,2,CC(=O)Nc1ccc(C=CC(=O)O)cc1.C[C@@H]1CC[C@@H](NCCN(C)C)CC1>>CC(=O)Nc1ccc(C=CC(=O)N(CCN(C)C)[C@@H]2CC[C@@H](C)CC2)cc1 -US06635641B2,2,CC(=O)OC(C)=O.Nc1ccc(Br)cn1>>CC(=O)Nc1ccc(Br)cn1 -US20090247507A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1cncnc1>>CC(C)(C)OC(=O)N1CCN(Cc2cncnc2)CC1 -US07951805B2,2,CC(C)CCNC(=O)c1ccc(N2CCC(N)C2)nn1.O=C(Cl)c1ccccc1C(F)(F)F>>CC(C)CCNC(=O)c1ccc(N2CCC(NC(=O)c3ccccc3C(F)(F)F)C2)nn1 -US04448961,2,CCOC(=O)NC(=O)C(C#N)=CNNc1c(Cl)cc(Cl)cc1Cl>>N#Cc1cn(Nc2c(Cl)cc(Cl)cc2Cl)c(=O)[nH]c1=O -US20070105860A1,2,COC(=O)c1ccc(-c2cc(N)ccc2C)cc1.O=C(O)c1ccoc1>>COC(=O)c1ccc(-c2cc(NC(=O)c3ccoc3)ccc2C)cc1 -US08507535B2,6,CC1(COc2ccc(Cl)cn2)CN(Cc2ccccc2)CC1c1ccc(Cl)cc1>>CC1(COc2ccc(Cl)cn2)CNCC1c1ccc(Cl)cc1 -US07850955B2,2,CCCCCCCCCCCC(=O)Cl.NC(=O)CC[C@H](N)C(=O)O>>CCCCCCCCCCCC(=O)N[C@@H](CCC(N)=O)C(=O)O -US20100168101A1,1,NNS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1.O=C1Nc2ccc(I)cc2C1=O>>O=C1Nc2ccc(I)cc2C1=NNS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1 -US20100048537A1,1,Clc1ccc(OC2CNCc3occc32)cc1Cl.OCCI>>OCCN1Cc2occc2C(Oc2ccc(Cl)c(Cl)c2)C1 -US20040181062A1,1,C(=Cc1nc2ccccc2[nH]1)c1ccccc1.N#Cc1cccnc1Cl>>N#Cc1cccnc1-n1c(/C=C/c2ccccc2)nc2ccccc21 -US20060247179A1,3,C#Cc1csc2cccc(OC)c12.O=C(O)c1ccc(I)cc1>>COc1cccc2scc(C#Cc3ccc(C(=O)O)cc3)c12 -US07214824B2,1,CC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1.CS(N)(=O)=O>>CC(=O)c1ccc(NS(C)(=O)=O)c(C)c1 -US20130225552A1,6,CC1(c2ccc(N[C@@H]3C[C@@H](N4C(=O)C(C)(C)c5cccnc54)C3)nc2)OCCO1>>CC(=O)c1ccc(N[C@@H]2C[C@@H](N3C(=O)C(C)(C)c4cccnc43)C2)nc1 -US05371063,2,CN(C)S(=O)(=O)Cl.COC(=O)c1ccccc1O>>COC(=O)c1ccccc1OS(=O)(=O)N(C)C -US20100137309A1,2,CCNCC.CCOC(=O)c1cc(-c2ccnc(Nc3cccc(Cl)c3)n2)ccn1>>CCN(CC)C(=O)c1cc(-c2ccnc(Nc3cccc(Cl)c3)n2)ccn1 -US20100331312A1,2,C[C@@H]1CCCN1CCc1ccc(-c2ccc3c(c2)CNC3)cc1.O=C(O)CO>>C[C@@H]1CCCN1CCc1ccc(-c2ccc3c(c2)CN(C(=O)CO)C3)cc1 -US06165941,1,C#CCBr.CC(C)n1c(=O)[nH]c2cc(-c3ncc(C(F)(F)F)cc3Cl)ccc21>>C#CCn1c(=O)n(C(C)C)c2ccc(-c3ncc(C(F)(F)F)cc3Cl)cc21 -US04183856,2,CC(C)(C)c1cc(N)no1.CCN(CC)C(=O)Cl>>CCN(CC)C(=O)Nc1cc(C(C)(C)C)on1 -US20150182509A1,1,CCOc1ccc(CCBr)cc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>CCOc1ccc(CCn2c3c(c4cc(C)ccc42)CN(C)CC3)cc1 -US20030069292A1,1,CC(C)C(=O)Cl.c1ccc(Oc2ccc(-c3cc[nH]n3)cc2)cc1>>CC(C)C(=O)n1ccc(-c2ccc(Oc3ccccc3)cc2)n1 -US20090221555A1,7,COc1ccc2c(c1[N+](=O)[O-])CN(Cc1ccccc1)CC(=O)N2>>COc1ccc2c(c1N)CN(Cc1ccccc1)CC(=O)N2 -US20120295897A1,1,ClCc1ncccc1Cl.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCO3>>O=C1N(Cc2ncccc2Cl)c2ccccc2C12COc1cc3c(cc12)OCCO3 -US20050004092A1,6,CC(C)(C)OC(=O)N1CC[C@H](SC(=O)c2ccccc2)C1>>O=C(S[C@H]1CCNC1)c1ccccc1 -US20110082135A1,9,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(Cl)nc4cc3-c3ccccc3)cc2)CCC1.NN>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(NN)nc4cc3-c3ccccc3)cc2)CCC1 -US05650422,6,CCOc1ccc(OCC(=O)OC(C)(C)C)c2c1C(=O)N(CSc1nnnn1-c1ccccc1)S2(=O)=O>>CCOc1ccc(OCC(=O)O)c2c1C(=O)N(CSc1nnnn1-c1ccccc1)S2(=O)=O -US20150148375A1,6,Cc1ccc(S(=O)(=O)n2ccc3c(-c4cc5c(cc4Oc4ccc(F)cc4F)nnn5C4CCCCO4)cn(C)c(=O)c32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(-c4cc5[nH]nnc5cc4Oc4ccc(F)cc4F)cn(C)c(=O)c32)cc1 -US09051325B2,1,CCN1c2cc(Cl)nc(=O)n2CC1(C)C.OCc1cccc(F)c1F>>CCN1c2cc(OCc3cccc(F)c3F)nc(=O)n2CC1(C)C -US08318760B2,1,COC(=O)c1ccc(CBr)cc1.Oc1cc(-c2ccc(OC(F)(F)F)cc2)cc2ccccc12>>COC(=O)c1ccc(COc2cc(-c3ccc(OC(F)(F)F)cc3)cc3ccccc23)cc1 -US05112977,1,C1CCNCC1.O=C1c2ccc(F)cc2C(=O)c2cc3ccccc3cc21>>O=C1c2ccc(N3CCCCC3)cc2C(=O)c2cc3ccccc3cc21 -US08026255B2,1,CC(C)(C)OC(=O)N1CCC(N)CC1.CS(=O)(=O)c1ccc(Br)nc1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(S(C)(=O)=O)cn2)CC1 -US04418077,7,NC(CF)C(F)C(=O)O>>NC(CF)C(F)CO -US20140154179A1,6,CCOC(=O)c1ccn(-c2cccc(F)c2)n1>>O=C(O)c1ccn(-c2cccc(F)c2)n1 -US20090018122A1,1,C#CCBr.CCOCc1nc2c(N)nc3cc(O)ccc3c2n1CC(C)(C)O>>C#CCOc1ccc2c(c1)nc(N)c1nc(COCC)n(CC(C)(C)O)c12 -US06399606B1,3,C=O.CCOC(=O)CCC(=O)c1cccnc1>>C=C(CC(=O)OCC)C(=O)c1cccnc1 -US08987256B2,10,Cc1ccc([C@@H](C(=O)OC(C)(C)C)C2CCCC2)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)[C@H](c1ccc(CBr)cc1)C1CCCC1 -US20130040930A1,1,CC1NC(=O)N(C)C1=O.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2F)CC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3C(=O)N(C)C(=O)C3C)cc2F)CC1 -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)Cc4c[nH]c5ccccc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](Cc4c[nH]c5ccccc45)NC(=O)c4c[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US06521643B1,1,Cc1ccnc(F)c1.O=[N+]([O-])c1cccc(O)c1>>Cc1ccnc(Oc2cccc([N+](=O)[O-])c2)c1 -US20110144056A1,2,CCN.O=C(O)c1ccc(-c2nn(-c3ccccc3)cc2Sc2ccc(Cl)cc2)cc1>>CCNC(=O)c1ccc(-c2nn(-c3ccccc3)cc2Sc2ccc(Cl)cc2)cc1 -US20110124634A1,6,CCOC(=O)c1c(Cl)[nH]c(C=O)c1C>>Cc1c(C=O)[nH]c(Cl)c1C(=O)O -US20100298287A1,8,OCc1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1C(F)(F)F>>O=Cc1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1C(F)(F)F -US08791102B2,2,CCOCCN1CCN(CC(=O)O)CC1.N[C@@H](COCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1>>CCOCCN1CCN(CC(=O)N[C@@H](COCc2ccccc2)C(=O)Nc2ccc(Oc3ccc(F)cc3)cc2)CC1 -US06153589,7,CCCCCCCCCCCC#CCO>>CCCCCCCCCCC/C=C/CO -US08158733B2,3,Brc1ccc2cccc(Br)c2n1.COc1c(B(O)O)cc(C(C)(C)C)cc1C(C)(C)C>>COc1c(-c2ccc3cccc(Br)c3n2)cc(C(C)(C)C)cc1C(C)(C)C -US06642384B1,1,COc1cc2c(cc1OC)CN(C(=O)OC(C)(C)C)[C@H](C(=O)O)C2.ClCc1ccccc1>>COc1cc2c(cc1OC)CN(C(=O)OC(C)(C)C)[C@H](C(=O)OCc1ccccc1)C2 -US20050222186A1,3,Brc1cnc(NCc2ccccn2)nc1NC1CCN(Cc2ccccc2)CC1.OB(O)c1ccsc1>>c1ccc(CN2CCC(Nc3nc(NCc4ccccn4)ncc3-c3ccsc3)CC2)cc1 -US08324257B2,1,CC(C)(C)OC(=O)NNC(=O)OC(C)(C)C.O=C(CCCl)c1ccccc1>>CC(C)(C)OC(=O)NN(CCC(=O)c1ccccc1)C(=O)OC(C)(C)C -US20150119362A1,1,Clc1cccc(-c2nc(Cl)c3c(n2)CCC3)c1.Nc1ccc(CCO)cc1>>OCCc1ccc(Nc2nc(-c3cccc(Cl)c3)nc3c2CCC3)cc1 -US20140303156A1,2,Fc1ccc2c(c1F)CCN2.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c1ccc(F)c2F -US20140303186A1,10,Cc1nn(C(=O)OC(C)(C)C)c2ncccc12.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)n1nc(CBr)c2cccnc21 -US20070244113A1,9,COc1ccc(N(C)c2nc(Cl)nc3ccccc23)cc1.[N-]=[N+]=[N-]>>COc1ccc(N(C)c2nc(N=[N+]=[N-])nc3ccccc23)cc1 -US20150210640A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc2cc(N)ccc2[nH]1>>CCOC(=O)c1cc2cc(NC(=O)OC(C)(C)C)ccc2[nH]1 -US20150141406A1,9,COC1NC=C(C(N)=O)c2c1c(Br)cn2C1CCCC1>>COC1NC=C(C#N)c2c1c(Br)cn2C1CCCC1 -US20080221114A1,1,C[C@@H]1C[C@H](C)CN(C(=O)C2Cc3ccccc3N2)C1.Clc1ncccn1>>C[C@@H]1C[C@H](C)CN(C(=O)C2Cc3ccccc3N2c2ncccn2)C1 -US20060004009A1,2,N[C@H]1CCC[C@H]1N.O=S(=O)(Cl)c1cc2cc(Cl)ccc2n1S(=O)(=O)c1ccccc1>>N[C@H]1CCC[C@H]1NS(=O)(=O)c1cc2cc(Cl)ccc2n1S(=O)(=O)c1ccccc1 -US05736487,2,CC(Cl)C(=O)Cl.COC(=O)Nc1ccc(OCc2nc3ccccc3s2)cc1C>>COC(=O)N(C(=O)C(C)Cl)c1ccc(OCc2nc3ccccc3s2)cc1C -US08063234B2,8,CSCc1cccc2c(C(CCC#N)c3ccc(C(F)(F)F)cc3)c[nH]c12.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cccc2c(C(CCC#N)c3ccc(C(F)(F)F)cc3)c[nH]c12 -US06693099B2,2,CC(C)(C)OC(=O)N1CCCC(C(=O)O)C1.NC(CCCc1ccccc1)CCCc1ccccc1>>CC(C)(C)OC(=O)N1CCCC(C(=O)NC(CCCc2ccccc2)CCCc2ccccc2)C1 -US06136823,1,CN.Cc1c(F)c(F)cc2c1c(=O)c(C(=O)O)cn2-c1cc(N)c(F)cc1F>>CNc1cc2c(c(C)c1F)c(=O)c(C(=O)O)cn2-c1cc(N)c(F)cc1F -US20080039476A1,2,CC1NCCc2c(Br)coc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2occ(Br)c2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US20150018343A1,1,CNCCOc1ccccc1C(=O)N1Cc2nn3c(C)c(Cl)c(C)nc3c2C1.FCCBr>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OCCN(C)CCF)C3 -US20150203472A1,3,CS(=O)(=O)c1ccc(-n2cnc3ccc(Br)cc32)cc1.OB(O)c1ccnn1-c1ccc(Cl)cc1>>CS(=O)(=O)c1ccc(-n2cnc3ccc(-c4ccnn4-c4ccc(Cl)cc4)cc32)cc1 -US06107312,1,CN(C)CCCl.Cc1c(SCc2ccco2)ccnc1CSc1nc2ccccc2[nH]1>>Cc1c(SCc2ccco2)ccnc1CSc1nc2ccccc2n1CCN(C)C -US20090325964A1,2,CC(C)(C)OC(=O)N1CCNCC1.COc1ccc(C(=O)O)cc1C#Cc1ccccn1>>COc1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1C#Cc1ccccn1 -US04446141,6,COc1ccc(C(OC(C)=O)C(C)N2CCC(n3c(=O)n(C(C)=O)c4ccccc43)CC2)cc1OC>>COc1ccc(C(OC(C)=O)C(C)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)cc1OC -US20080038242A1,6,CCOC(=O)COc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1>>O=C(O)COc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 -US20040048916A1,2,O=C(O)c1ccc(C(F)(F)F)cc1C(=O)O>>O=C1OC(=O)c2cc(C(F)(F)F)ccc21 -US06284764B1,1,CCC=O.Cc1cc(Nc2ncnc3ccc(C#CC4CCCNC4)cc23)ccc1Oc1ccccc1>>CCCN1CCCC(C#Cc2ccc3ncnc(Nc4ccc(Oc5ccccc5)c(C)c4)c3c2)C1 -US05693809,2,C[SiH](C)OC[C@]12CC[C@H]3[C@@H](CC=C4NC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(C)(C)C.O=C(Cl)c1ccccc1>>C[SiH](C)OC[C@]12CC[C@H]3[C@@H](CC=C4N(C(=O)c5ccccc5)C(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(C)(C)C -US20100075968A1,2,CN1C(=O)N(c2cnccn2)CC1C(=O)O.NCc1cccc(C(F)(F)F)c1Cl>>CN1C(=O)N(c2cnccn2)CC1C(=O)NCc1cccc(C(F)(F)F)c1Cl -US20080234384A1,1,CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1.O=C(O)c1cc(F)ccc1S>>CS(=O)(=O)c1ccc(C(=O)O)c(Sc2ccc(F)cc2C(=O)O)c1 -US08063035B2,6,CC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NC(C)c1ccc(F)cc1-c1cccc2cc(-c3nc(NCCn4ccnn4)ncc3F)sc12>>C[C@@H](N)C(=O)N[C@H](C)c1ccc(F)cc1-c1cccc2cc(-c3nc(NCCn4ccnn4)ncc3F)sc12 -US04138579,1,C#CCBr.CC(=CCOc1ccc(C(=O)O)cc1)CCC(C)=C(C)C>>C#CCOC(=O)c1ccc(OCC=C(C)CCC(C)=C(C)C)cc1 -US20120208819A1,1,C[C@@H](N)c1ccc(Br)cc1.C[C@H](NC(=O)c1nc(C#N)cnc1F)c1ccc(F)c(F)c1>>C[C@H](NC(=O)c1nc(C#N)cnc1N[C@H](C)c1ccc(Br)cc1)c1ccc(F)c(F)c1 -US20100256140A1,2,O=C(Cl)N1CCCCC1.O=C(c1c[nH]c2cc(Cl)ccc12)N1CCC(n2c(=O)[nH]c3ccccc32)CC1>>O=C(c1cn(C(=O)N2CCCCC2)c2cc(Cl)ccc12)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 -US09132126B2,6,COC(=O)c1c(-c2cccc(F)c2)noc1N>>Nc1onc(-c2cccc(F)c2)c1C(=O)O -US20140162997A1,7,CC1(C)CC(=O)CC(C)(C)O1>>CC1(C)CC(O)CC(C)(C)O1 -US08552049B2,3,C#CCO.Clc1cc(Cl)c(I)c(Cl)c1>>OCC#Cc1c(Cl)cc(Cl)cc1Cl -US06521620B1,9,N.O=C(O)c1ccc(F)nc1F>>NC(=O)c1ccc(F)nc1F -US08790619B2,6,CCOC(=O)C1CCCc2c1c1ccccc1n2CCF>>O=C(O)C1CCCc2c1c1ccccc1n2CCF -US20050004186A1,7,C#Cc1ccc(Nc2c(-c3nnc(NC[C@@H](O)CO)o3)ccc(F)c2F)c(F)c1>>CCc1ccc(Nc2c(-c3nnc(NC[C@@H](O)CO)o3)ccc(F)c2F)c(F)c1 -US08410117B2,2,CCOC(=O)c1cnn(CC)c1C(=O)O.Nc1ccn2cc(-c3ccccc3)nc2n1>>CCOC(=O)c1cnn(CC)c1C(=O)Nc1ccn2cc(-c3ccccc3)nc2n1 -US08623857B2,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.C[Si](C)(C)CCOCCl>>CC1(C)OB(c2cnn(COCC[Si](C)(C)C)c2)OC1(C)C -US20090192138A1,6,CCNC(=O)c1cccnc1Cn1c(=O)c2c(c(C#N)c(N3CCCN(C(=O)OC(C)(C)C)CC3)n2CC=C(C)C)n(C)c1=O>>CCNC(=O)c1cccnc1Cn1c(=O)c2c(c(C#N)c(N3CCCNCC3)n2CC=C(C)C)n(C)c1=O -US20140179662A1,1,C1CCNC1.NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1>>NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCCC3)n2)c1 -US20100076187A1,1,N#Cc1ccc(NC2CCNCC2)nn1.O=Cc1ccc(C(F)(F)F)cc1>>N#Cc1ccc(NC2CCN(Cc3ccc(C(F)(F)F)cc3)CC2)nn1 -US20130040930A1,1,C[C@@H]1CCS(=O)(=O)N1.Cc1cc(C)c(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2)nc1C>>Cc1cc(C)c(N2CCN(C(=O)c3ccc(N4[C@H](C)CCS4(=O)=O)cc3S(C)(=O)=O)CC2)nc1C -US20070249670A1,2,COC(=O)[C@@H](N)[C@@H](C)OC(C)(C)C.O=C(O)c1ccc(-c2ccc(F)c(F)c2)cc1[N+](=O)[O-]>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1[N+](=O)[O-])[C@@H](C)OC(C)(C)C -US07361659B2,2,Cc1nc(N)sc1S(=O)(=O)NC(C)(CO)CO.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>Cc1nc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)sc1S(=O)(=O)NC(C)(CO)CO -US20110009454A1,2,COCc1ccc(C(=O)O)c(N)n1.Cc1ccc(Oc2cccc(CN)c2)cc1>>COCc1ccc(C(=O)NCc2cccc(Oc3ccc(C)cc3)c2)c(N)n1 -US08791129B2,3,CC1(C)OB(c2ccc3nc(N)nc(C(=O)N4Cc5ccccc5C4)c3c2)OC1(C)C.O=Cc1ccc(F)cc1Br>>Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3cc(F)ccc3C=O)ccc2n1 -US20040248887A1,2,C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@@H](N)CC1CCCCC1.O=S(=O)(Cl)c1cccc(Cl)c1>>C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC1CCCCC1)NS(=O)(=O)c1cccc(Cl)c1 -US20120277220A1,1,C1CN(C2CC2)CCN1.O=[N+]([O-])c1ccc(F)cc1OC(F)F>>O=[N+]([O-])c1ccc(N2CCN(C3CC3)CC2)cc1OC(F)F -US20070287838A1,7,CSc1cc(O)ccc1[N+](=O)[O-]>>CSc1cc(O)ccc1N -US06677369B2,2,CCOc1ccc(C(=O)Cl)cc1.N#Cc1cccc(C(=O)Nc2ccccc2N)c1>>CCOc1ccc(C(=O)Nc2ccccc2NC(=O)c2cccc(C#N)c2)cc1 -US09072731B2,6,CCOC(=O)c1sc(-c2ccc(Cl)cc2)cc1-c1ccc(S(N)(=O)=O)cc1>>NS(=O)(=O)c1ccc(-c2cc(-c3ccc(Cl)cc3)sc2C(=O)O)cc1 -US07651630B2,3,COC(=O)C1CCC(=O)CC1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>COC=C1CCC(C(=O)OC)CC1 -US20080262244A1,7,Cc1c(C(=O)O)cccc1[N+](=O)[O-]>>Cc1c(CO)cccc1[N+](=O)[O-] -US20150152063A1,1,COC[C@H](C)NC(=NC(=O)c1ccc(F)c(F)c1)Nc1n[nH]c2cc(C(F)(F)F)ccc12.CSCCl>>COC[C@H](C)NC(=NC(=O)c1ccc(F)c(F)c1)Nc1nn(CSC)c2cc(C(F)(F)F)ccc12 -US09006252B2,1,ClCCCOc1ccc2c(Cl)ncnc2c1.NCCc1ccc(N)cc1>>Nc1ccc(CCNc2ncnc3cc(OCCCCl)ccc23)cc1 -US20140142085A1,6,CC(C)(C)OC(=O)NCc1ccc2c(CC(=O)N[C@@H](Cc3cc(F)cc(F)c3)c3ncccc3-c3cccc(C(N)=O)c3)c[nH]c2c1>>NCc1ccc2c(CC(=O)N[C@@H](Cc3cc(F)cc(F)c3)c3ncccc3-c3cccc(C(N)=O)c3)c[nH]c2c1 -US20140135332A1,1,CN(C)C(=O)C(Br)c1nc(-c2ccc(Cl)cc2)cs1.NC(=O)c1c(F)ccc(O)c1F>>CN(C)C(=O)C(Oc1ccc(F)c(C(N)=O)c1F)c1nc(-c2ccc(Cl)cc2)cs1 -US20140309193A1,6,CCOC(=O)c1c(OCC(N)=O)c(OCc2ccccc2)c(C(=O)OCC)n1-c1ccc(OC)cc1>>CCOC(=O)c1c(O)c(OCC(N)=O)c(C(=O)OCC)n1-c1ccc(OC)cc1 -US04370340,6,CCOC(=O)Cn1c(=O)oc2cc(-c3ccccc3)c(Cl)cc21>>O=C(O)Cn1c(=O)oc2cc(-c3ccccc3)c(Cl)cc21 -US20120046267A1,1,CC[O-].Clc1cc2ccsc2cn1>>CCOc1cc2ccsc2cn1 -US20080194629A1,9,CCCCCCC1(CN=[N+]=[N-])c2ccccc2Oc2ccccc21>>CCCCCCC1(CN)c2ccccc2Oc2ccccc21 -US20150166549A1,1,CC(Br)c1oc(=O)c2ccccc2c1-c1cccc(S(=O)(=O)N2CCOCC2)c1.Nc1ncnc2[nH]cnc12>>CC(c1oc(=O)c2ccccc2c1-c1cccc(S(=O)(=O)N2CCOCC2)c1)n1cnc2c(N)ncnc21 -US20060084643A1,1,N#Cc1ccsc1N.O=[N+]([O-])c1cc(F)c(F)cc1F>>N#Cc1ccsc1Nc1cc(F)c(F)cc1[N+](=O)[O-] -US20050239656A1,9,CC(C)C(O)c1c(C(F)(F)F)ccnc1Cl>>CC(C)C(O)c1cnccc1C(F)(F)F -US04001225,2,O=C(Cl)C=Cc1ccccc1.O=C(O)CO>>O=C(O)COC(=O)C=Cc1ccccc1 -US20150018341A1,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)C1.O=C(c1ccc(O)cc1)c1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C(=O)c3ccc(O)cc3)cc2)C1 -US20070161648A1,6,COc1cc(Br)c2c(c1)CNC2=O>>O=C1NCc2cc(O)cc(Br)c21 -US07879835B2,1,Brc1cccc(OCc2ccccc2)n1.C1CCNC1>>c1ccc(COc2cccc(N3CCCC3)n2)cc1 -US20040038982A1,5,COc1ccccc1C1CCNCC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccccc1C1CCN(C(=O)C(F)(F)F)CC1 -US20050096380A1,7,CCOC(=O)C(F)=C(CC)c1cc2c(cc1OC)OC(C)(C)C=C2C(C)C>>CC/C(=C(\F)CO)c1cc2c(cc1OC)OC(C)(C)C=C2C(C)C -US20150011545A1,9,Fc1ccc(Br)nc1.[C-]#N>>N#Cc1ccc(F)cn1 -US20110092553A1,1,COC(=O)c1ccc(CBr)cc1.Clc1ccc(-c2c[nH]c(Cc3ccc(Br)cc3)n2)c(Cl)c1>>COC(=O)c1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2Cc2ccc(Br)cc2)cc1 -US08039641B2,6,O=C(NC[C@@H](O)[C@@H]1C=CCO1)OCc1ccccc1>>NC[C@@H](O)[C@@H]1C=CCO1 -US20120028919A1,7,COc1cc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2O)ccc1[N+](=O)[O-]>>COc1cc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2O)ccc1N -US20120225854A1,2,O=S(=O)(Cl)c1cscc1Br.OC(c1ccc(N2CCNCC2)cc1)(C(F)(F)F)C(F)(F)F>>O=S(=O)(c1cscc1Br)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1 -US20100204206A1,7,CSc1ccccc1C(=O)O>>CSc1ccccc1CO -US20070244131A1,3,CC(C)(C(=O)O)c1cccc(B(O)O)c1.COc1nc(Cl)cc(NCc2ccsc2)n1>>COc1nc(NCc2ccsc2)cc(-c2cccc(C(C)(C)C(=O)O)c2)n1 -US07776897B2,1,C1CCCn2c(nnc2C2(C3CCNCC3)CCCC2)CC1.CO>>CN1CCC(C2(c3nnc4n3CCCCCC4)CCCC2)CC1 -US08222246B2,2,CC(C)N.COC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2CO)nc1>>CC(C)NC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2CO)nc1 -US20080004271A1,6,CC[C@H](CO)Nc1nc(-c2cc(Cl)cc(OC)c2)c2c(N)c(C(N)=O)sc2n1>>CC[C@H](CO)Nc1nc(-c2cc(O)cc(Cl)c2)c2c(N)c(C(N)=O)sc2n1 -US20070173498A1,2,CNc1ccc(C(=O)O)cc1.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)N(C)c2ccc(C(=O)O)cc2)cc1 -US20090099169A1,6,CCOC(=O)c1cc(C)n(Cc2cc(Cl)cc3cc(C(C)C)oc23)n1>>Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 -US20100279990A1,6,COCCCC#Cc1ccc2c(c1)[C@@H](N(C)C(=O)OC(C)(C)C)CC[C@H]2c1ccc(Cl)c(Cl)c1>>CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(C#CCCCOC)cc21 -US20060211678A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=c1[nH][nH]c2ccc([N+](=O)[O-])cc12>>CC(C)(C)OC(=O)n1[nH]c(=O)c2cc([N+](=O)[O-])ccc21 -US20150259343A1,1,NC(=O)CI.c1ccc2c(c1)NCCC2C1COC1>>NC(=O)CN1CCC(C2COC2)c2ccccc21 -US08455521B2,1,CN.O=C[C@H]([C@@H](O)C1CCCC1)N1C(=O)c2ccccc2C1=O>>CNC[C@H]([C@@H](O)C1CCCC1)N1C(=O)c2ccccc2C1=O -US20110275797A1,1,COC(=O)c1ccc(I)cc1OCc1ccccc1.c1c[nH]cn1>>COC(=O)c1ccc(-n2ccnc2)cc1OCc1ccccc1 -US04097264,2,CN(C)C(=O)Cl.CNc1nnc(C(C)(C)CCl)s1>>CN(C)C(=O)N(C)c1nnc(C(C)(C)CCl)s1 -US20080111473A1,3,Brc1ccc(Br)cc1.Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1>>Brc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 -US04215123,1,CCN.COC(=O)c1cccnc1Cl>>CCNc1ncccc1C(=O)OC -US20040236084A1,1,CN.Clc1nc(Cl)nc(NC2CCCC2)n1>>CNc1nc(Cl)nc(NC2CCCC2)n1 -US20110092526A1,1,CC(C)O.O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(Cl)nc1Cl>>CC(C)Oc1nc(Cl)ncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 -US06506738B1,2,CNCCO.O=C(Cl)OCc1ccccc1>>CN(CCO)C(=O)OCc1ccccc1 -US08420642B2,1,COc1ccc(Br)nc1.Cn1ccc(N)n1>>COc1ccc(Nc2ccn(C)n2)nc1 -US04072696,7,COC(=O)NC(=S)Nc1ccc(S(C)=O)cc1[N+](=O)[O-]>>COC(=O)NC(=S)Nc1ccc(S(C)=O)cc1N -US04320148,6,COc1ccc(SC)c2c1CC(NC(C)=O)CC2>>COc1ccc(SC)c2c1CC(N)CC2 -US20120053180A1,9,CS(=O)(=O)N1CCN(C(=O)CCCCl)CC1.[N-]=[N+]=[N-]>>CS(=O)(=O)N1CCN(C(=O)CCCN=[N+]=[N-])CC1 -US06001849,6,CC(C)(C)OC(=O)N1CCC[C@H]1c1cc2ncccc2o1>>c1cnc2cc([C@@H]3CCCN3)oc2c1 -US07091216B2,3,CC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)nc1OCC(=O)C(C)(C)C>>Cc1c(C(=O)C(C)(C)C)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12 -US05877191,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(-c2c[nH]nc2C)cc1Br>>COc1ccc(-c2cn(C(=O)OC(C)(C)C)nc2C)cc1Br -US20090258817A1,1,O=C(O)CCCCCBr.Oc1ccc(S)cc1>>O=C(O)CCCCCSc1ccc(O)cc1 -US20150099777A1,6,CCCc1nc2c(cc1C(=O)OC)C(=O)N(C1CCN(Cc3cc(C4CC4)c(-c4cccc(F)c4)cc3OCC)CC1)CC2>>CCCc1nc2c(cc1C(=O)O)C(=O)N(C1CCN(Cc3cc(C4CC4)c(-c4cccc(F)c4)cc3OCC)CC1)CC2 -US07468376B2,1,CNOC.O=C(Cl)c1ccc(F)cc1>>CON(C)C(=O)c1ccc(F)cc1 -US04395414,1,CCOC(=O)CBr.O=c1[nH]c2ccccc2cc1-c1ccccc1>>CCOC(=O)Cn1c(=O)c(-c2ccccc2)cc2ccccc21 -US04125732,1,COC(=O)C(Br)c1ccc(OCCCOc2ccc(Cl)cc2)cc1.Oc1ccc(Oc2ccccc2)cc1>>COC(=O)C(Oc1ccc(Oc2ccccc2)cc1)c1ccc(OCCCOc2ccc(Cl)cc2)cc1 -US09115144B2,9,BrCc1sccc1Br.[C-]#N>>N#CCc1sccc1Br -US08377923B2,2,CCOC(=O)CNC(=O)c1cc(Cl)ccc1OC(C)(C)c1nnc(-c2ccccc2C(F)(F)F)n1C.NC1CC1>>Cn1c(-c2ccccc2C(F)(F)F)nnc1C(C)(C)Oc1ccc(Cl)cc1C(=O)NCC(=O)NC1CC1 -US07338966B2,1,Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1.O=C1Nc2ccccc2C1=CO>>O=C1Nc2ccccc2/C1=C/Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1 -US20110060009A1,7,O=C(/C=C/c1ccc(CN2CCC[C@H]2C(=O)N2CCc3ccccc32)cc1)NO>>O=C(/C=C/c1ccc(CN2CCC[C@H]2CN2CCc3ccccc32)cc1)NO -US20080004271A1,6,CC(C)(CNC(=O)OC(C)(C)C)CNc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1>>CC(C)(CN)CNc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1 -US20120172382A1,6,COC(=O)c1cccn(-c2ccc(F)cc2)c1=O>>O=C(O)c1cccn(-c2ccc(F)cc2)c1=O -US04045438,9,CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3ccc(CCl)cc3)C2SC1.[N-]=[N+]=[N-]>>CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3ccc(CN=[N+]=[N-])cc3)C2SC1 -US07247654B2,6,COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2N(C)C(=O)C(F)(F)F)cc(OC)c1C>>CNc1cc(-c2noc(C)n2)ccc1CNC(=O)c1cc(OC)c(C)c(OC)c1 -US07935712B2,6,COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(C(C)(C)C(=O)OCc4ccccc4)ccc2O3)nc2c(OC)cccc12>>COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(C(C)(C)C(=O)O)ccc2O3)nc2c(OC)cccc12 -US20040142920A1,1,CC(C)(C)OC(=O)N1CCC(Nc2ccc(Br)cc2)CC1.Ic1ccccc1>>CC(C)(C)OC(=O)N1CCC(N(c2ccccc2)c2ccc(Br)cc2)CC1 -US20080255152A1,5,CC(C)[Si](Oc1ccc(C=O)cc1)(C(C)C)C(C)C.OCCO>>CC(C)[Si](Oc1ccc(C2OCCO2)cc1)(C(C)C)C(C)C -US05280044,2,CC(C)(CCl)C(=O)Cl.CN(C)C(=O)c1ccc(N)cc1Cl>>CN(C)C(=O)c1ccc(NC(=O)C(C)(C)CCl)cc1Cl -US20030176454A1,8,Fc1ccc(-c2cccc3cnccc23)cc1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc2c(-c3ccc(F)cc3)cccc2c1 -US20150191464A1,2,CC(C)(O)[C@H](F)CN.O=C(O)c1cnc(Cl)cc1Cl>>CC(C)(O)[C@H](F)CNC(=O)c1cnc(Cl)cc1Cl -US20020193560A1,2,CCCCCCOc1ccc(CCC(=O)NN)cc1.COC(=O)c1ccc(C(=O)Cl)cc1>>CCCCCCOc1ccc(CCC(=O)NNC(=O)c2ccc(C(=O)OC)cc2)cc1 -US20120309796A1,3,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1cccc(Br)c1.CC(C)c1cccc(B(O)O)c1>>CC(C)c1cccc(-c2cccc(S(=O)(=O)NC3CCCCc4c(OCC(=O)OC(C)(C)C)cccc43)c2)c1 -US20090170916A1,4,CCOC(=O)C(=O)CC(=O)CCC1C(C)CCCC1(C)C.NN>>CCOC(=O)c1cc(CCC2C(C)CCCC2(C)C)[nH]n1 -US20140275003A1,1,C1COCCN1.O=c1[nH]cc(Br)nc1Br>>O=c1[nH]cc(Br)nc1N1CCOCC1 -US09034877B2,2,CCCN(CCN1CCNCC1)C1CCc2c(O)cccc2C1.O=C(O)c1cc2ccccc2[nH]1>>CCCN(CCN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1)C1CCc2c(O)cccc2C1 -US07572809B2,1,COc1cc2cc(Nc3cc(C)[nH]n3)nc(Cl)c2cc1OC.OC1CCCC1>>COc1cc2cc(Nc3cc(C)[nH]n3)nc(OC3CCCC3)c2cc1OC -US07427683B2,2,Cc1cccc(N)c1N1CCCCC1.N#Cc1ccc(C(=O)Cl)o1>>Cc1cccc(NC(=O)c2ccc(C#N)o2)c1N1CCCCC1 -US20150274704A1,6,CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CCC2(CC1)CCN(C(=O)OC(C)(C)C)C2>>CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CCC2(CCNC2)CC1 -US20100119503A1,7,CC(C)[C@]1(C(=O)N2CC=C(c3cccc(C(F)(F)F)c3)CC2)CC[C@@H](NC2CCOCC2)C1>>CC(C)[C@]1(C(=O)N2CCC(c3cccc(C(F)(F)F)c3)CC2)CC[C@@H](NC2CCOCC2)C1 -US06960578B2,2,CC(C)(C)OC(=O)CC(=O)c1csc(-n2ccnc2)n1.CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2F)cc1N>>CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2F)cc1NC(=O)CC(=O)c1csc(-n2ccnc2)n1 -US04066457,7,O=C(O)c1cc([N+](=O)[O-])ccc1N1CCCC1>>Nc1ccc(N2CCCC2)c(C(=O)O)c1 -US05654320,2,CC(C)n1nc(C(=O)NCCN2CCC(N)CC2)c2ccccc21.O=C(O)C12CC3CC(CC(O)(C3)C1)C2>>CC(C)n1nc(C(=O)NCCN2CCC(NC(=O)C34CC5CC(CC(O)(C5)C3)C4)CC2)c2ccccc21 -US20080176832A1,2,CC(C)(C)OC(=O)N1CCc2cn(-c3ccc(C(=O)O)cc3)nc2CC1.CNC>>CN(C)C(=O)c1ccc(-n2cc3c(n2)CCN(C(=O)OC(C)(C)C)CC3)cc1 -US20080139484A1,2,CC(C)(NC(=O)OCc1ccccc1)C(=O)O.CCOC(=O)[C@@H](N)CO>>CCOC(=O)[C@H](CO)NC(=O)C(C)(C)NC(=O)OCc1ccccc1 -US07166599B2,7,CNc1nc(Nc2ccc(Cl)cc2)ncc1[N+](=O)[O-]>>CNc1nc(Nc2ccc(Cl)cc2)ncc1N -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(-c5ccccc5)cc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cc1[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc2c1C(=O)O>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccc(-c5ccccc5)cc4)NC(=O)c4c(C)[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US05739142,1,CCc1cc(N2CCCCC2)c(S(C)(=O)=O)cc1C(=O)Cl.N=C(N)N>>CCc1cc(N2CCCCC2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N -US20050197338A1,3,CCOc1cc(-n2cc(NC(N)=O)c(C(N)=O)n2)ccc1Br.OB(O)c1cccc(O)c1>>CCOc1cc(-n2cc(NC(N)=O)c(C(N)=O)n2)ccc1-c1cccc(O)c1 -US05604004,1,NNc1ccccn1.O=Cc1ccccc1>>C(=NNc1ccccn1)c1ccccc1 -US05202346,2,CS(=O)(=O)Nc1ccc(C(=O)O)cc1.Cc1cccc(CCN2CCNCC2)n1>>Cc1cccc(CCN2CCN(C(=O)c3ccc(NS(C)(=O)=O)cc3)CC2)n1 -US20100256356A1,3,Cn1c(CC2CCCCC2)ncc(Br)c1=O.OB(O)c1ccc(OCc2ccccc2)c(F)c1>>Cn1c(CC2CCCCC2)ncc(-c2ccc(OCc3ccccc3)c(F)c2)c1=O -US20150023913A1,7,C[C@]1(COC(=O)c2ccccc2)C=CCCCO1>>C[C@]1(CO)C=CCCCO1 -US20060025400A1,2,Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)O)cc1.N[C@@H]1CCCc2cc(CCN3CCCCC3)ccc21>>Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)N[C@@H]2CCCc3cc(CCN4CCCCC4)ccc32)cc1 -US07067534B1,1,CC(=O)c1cccc(O)c1.O[C@H](CCCl)c1ccccc1>>CC(=O)c1cccc(O[C@@H](CCCl)c2ccccc2)c1 -US06518268B1,3,CCCC[Sn](CCCC)(CCCC)c1ccco1.O=Cc1cc(Br)ccc1F>>O=Cc1cc(-c2ccco2)ccc1F -US20090226398A1,1,COC(=O)c1cc(CBr)ccc1-c1ccc(OC)cc1C(F)(F)F.Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F>>COC(=O)c1cc(Cn2cc3nc(-c4cccc(F)c4F)nc-3cn2)ccc1-c1ccc(OC)cc1C(F)(F)F -US20130079303A1,6,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(OCc4ccccc4)cnc3F)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(O)cnc3F)n2)cc1 -US20060276433A1,7,Cc1nc(-c2ccc([N+](=O)[O-])cc2)no1>>Cc1nc(-c2ccc(N)cc2)no1 -US04937251,1,BrCCCCBr.OCCc1ccccn1>>BrCCCCOCCc1ccccn1 -US20150011526A1,2,CC(=O)OC(C)=O.O=C1CCCCN1c1ccccc1CCN1CCC(C2CCCCN2)C1>>CC(=O)N1CCCCC1C1CCN(CCc2ccccc2N2CCCCC2=O)C1 -US20080312234A1,6,COC(=O)C=Cc1ccc(Br)nc1>>O=C(O)C=Cc1ccc(Br)nc1 -US20140011800A1,3,CO[C@H]1CN(c2ncc(C#N)cn2)C[C@H]1Nc1c(C(N)=O)cnn2cc(Br)cc12.O=C(NC1CC1)c1ccc(B(O)O)cc1>>CO[C@H]1CN(c2ncc(C#N)cn2)C[C@H]1Nc1c(C(N)=O)cnn2cc(-c3ccc(C(=O)NC4CC4)cc3)cc12 -US09040693B2,1,CC(C)(O)c1ccccc1.O=[N+]([O-])c1cc(O)ccc1Cl>>CC(C)(Oc1ccc(Cl)c([N+](=O)[O-])c1)c1ccccc1 -US08486939B2,1,FC(F)c1nc2ccccc2n1-c1nc(Cl)cc(Cl)n1.Nc1cccnc1>>FC(F)c1nc2ccccc2n1-c1nc(Cl)cc(Nc2cccnc2)n1 -US06197959B1,1,COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)NCCC3)cc1.OCCBr>>COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)N(CCO)CCC3)cc1 -US08288413B2,1,CC(C)c1ccc(NC(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c(Br)c1>>CC(C)c1ccc2[nH]c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c2c1 -US07737166B2,2,CC(C)(C)C(=O)OC(=O)C(C)(C)C.CNc1nc2c(C#N)c(C)c(-c3ccccc3)c(N3CC[C@H](N(C)C)C3)c2o1>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(N(C)C(=O)C(C)(C)C)nc2c1C#N -US20110275797A1,1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(Br)ccc1OCc1ccccc1.CC(C)(C)[Si](C)(C)OC1CCNCC1>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(N2CCC(O[Si](C)(C)C(C)(C)C)CC2)ccc1OCc1ccccc1 -US07592477B2,7,O=[N+]([O-])c1ccc(-c2cccc3c2oc2ccccc23)cc1>>Nc1ccc(-c2cccc3c2oc2ccccc23)cc1 -US20040006141A1,1,BrCc1ccccc1.CCOC(=O)C(O)Cc1ccc(O)cc1>>CCOC(=O)C(O)Cc1ccc(OCc2ccccc2)cc1 -US20120184553A1,2,CN1CCN(S(=O)(=O)c2ccc(OCc3ccccc3)c(C(=O)O)c2)CC1.Nc1cccnc1>>CN1CCN(S(=O)(=O)c2ccc(OCc3ccccc3)c(C(=O)Nc3cccnc3)c2)CC1 -US20150232469A1,1,CC(C)N.Fc1ccc(OC2CCN(c3nc4ccncc4nc3F)CC2)c(F)c1>>CC(C)Nc1nc2cnccc2nc1N1CCC(Oc2ccc(F)cc2F)CC1 -US20060264405A1,8,CN(CCO)C(=O)OC(C)(C)C>>CN(CC=O)C(=O)OC(C)(C)C -US07071340B2,6,C=C1C=Cc2cc(C(=O)OC)ccc2OC1>>C=C1C=Cc2cc(C(=O)O)ccc2OC1 -US20140088079A1,2,C1COCCN1.CC1(C)O[C@@H]2O[C@@H](C(=O)O)[C@@H](O)[C@@H]2O1>>CC1(C)O[C@@H]2O[C@@H](C(=O)N3CCOCC3)[C@@H](O)[C@@H]2O1 -US08383642B2,1,BrCc1ccc(CBr)cc1.CC#C[C@@H](CC(=O)OCC)c1ccc(O)cc1>>CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc(CBr)cc2)cc1 -US07960419B2,2,CC(F)(F)c1ccc(-c2cc(N)sn2)cc1.C[C@@H]1C[C@H]1C(=O)OCc1ccccc1>>C[C@@H]1C[C@H]1C(=O)Nc1cc(-c2ccc(C(C)(F)F)cc2)ns1 -US20080132504A1,1,CNS(=O)(=O)c1ccccc1N.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CNS(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1[N+](=O)[O-] -US20100249163A1,1,C=CCBr.COCCc1ccc(Cl)c(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(F)c(F)c2)C2CC2)c1>>C=CCO[C@]1(c2ccc(F)c(F)c2)CCN(C(=O)OC(C)(C)C)C[C@@H]1C(=O)N(Cc1cc(CCOC)ccc1Cl)C1CC1 -US05539112,1,CC(C)(C)C(=O)Nc1ccc(-c2cc(=O)c3c(N)c(F)cc(F)c3o2)cc1F.CCCCCCI>>CCCCCCNc1c(F)cc(F)c2oc(-c3ccc(NC(=O)C(C)(C)C)c(F)c3)cc(=O)c12 -US20100137610A1,2,CN(c1cccc2cc(C3=NCC4(CCNCC4)S3)[nH]c12)S(=O)(=O)c1cccs1.CS(=O)(=O)Cl>>CN(c1cccc2cc(C3=NCC4(CCN(S(C)(=O)=O)CC4)S3)[nH]c12)S(=O)(=O)c1cccs1 -US09029536B2,3,CCOC(=O)C=C(c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)c1nc2ccccc2n1COCC[Si](C)(C)C.CCn1nc(Br)c2ncccc21>>CCOC(=O)C=C(c1ccc(-c2nn(CC)c3cccnc23)cc1)c1nc2ccccc2n1COCC[Si](C)(C)C -US06872731B2,3,CCCC[Sn](CCCC)(CCCC)c1cccc(-c2cccnc2)c1.Clc1ccn2c(Br)cnc2c1>>Clc1ccn2c(-c3cccc(-c4cccnc4)c3)cnc2c1 -US09156876B2,7,C=CC(C)c1cc2c(cc1O)CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@H]21>>CCC(C)c1cc2c(cc1O)CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@H]21 -US20080132551A1,1,CCOc1ccc([N+](=O)[O-])c(Br)c1.Nc1ccncc1>>CCOc1ccc([N+](=O)[O-])c(Nc2ccncc2)c1 -US20030199511A1,1,CC(C)(C)OC(=O)N[C@H](COc1cncc(-c2ccc(C=O)cc2)c1)Cc1c[nH]c2ccccc12.Nc1ccccc1>>CC(C)(C)OC(=O)N[C@H](COc1cncc(-c2ccc(CNc3ccccc3)cc2)c1)Cc1c[nH]c2ccccc12 -US05382598,2,CC(O)(C(=O)O)C(F)(F)F.COc1ccccc1S(=O)(=O)c1ccc(N)cc1>>COc1ccccc1S(=O)(=O)c1ccc(NC(=O)C(C)(O)C(F)(F)F)cc1 -US20130217702A1,2,Cc1nc(-c2c(Cl)c3cc(Cl)ccc3n2-c2ccc(CNC(=O)C3(N)CC3)cc2)no1.O=C(O)c1cccnc1Cl>>Cc1nc(-c2c(Cl)c3cc(Cl)ccc3n2-c2ccc(CNC(=O)C3(NC(=O)c4cccnc4Cl)CC3)cc2)no1 -US20020132810A1,2,CC(C)CCC(CC(O)C(N)Cc1ccccc1)S(=O)(=O)c1ccccc1.O=C(O)c1cnc2ccccc2n1>>CC(C)CCC(CC(O)C(Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)S(=O)(=O)c1ccccc1 -US20090176786A1,2,CN(C(=O)Cl)c1ccc(SC(F)(F)F)cc1F.NC1CCCCC1>>CN(C(=O)NC1CCCCC1)c1ccc(SC(F)(F)F)cc1F -US06153641,1,CC(=O)OCc1ccc(CBr)cc1OCOCC[Si](C)(C)C.Cn1cc(C2=C(c3c[nH]c4ccccc34)C(=O)OC2=O)c2ccccc21>>CC(=O)OCc1ccc(Cn2cc(C3=C(c4cn(C)c5ccccc45)C(=O)OC3=O)c3ccccc32)cc1OCOCC[Si](C)(C)C -US05420122,4,CS(=O)(=O)O[C@@H]1C[C@@H](C(=O)CBr)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1.NC(N)=S>>CS(=O)(=O)O[C@@H]1C[C@@H](c2csc(N)n2)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1 -US07544690B2,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1.O=S(=O)(Cl)c1ccc(Br)cc1OC(F)(F)F>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](NS(=O)(=O)c2ccc(Br)cc2OC(F)(F)F)CC1 -US20090062358A1,6,CCCn1c(CCc2ccc(OC)cc2)nn(-c2ccc(C(F)(F)F)cc2)c1=O>>CCCn1c(CCc2ccc(O)cc2)nn(-c2ccc(C(F)(F)F)cc2)c1=O -US06117901,2,CCC(N)C(=O)OCC(C)C.O=C(O)Cc1cccc2scnc12>>CCC(NC(=O)Cc1cccc2scnc12)C(=O)OCC(C)C -US08809353B2,6,Cc1ccc2c(N3CC[C@@H](NC(=O)OCc4ccccc4)C3)nc(-c3c(O)cccc3F)nc2c1>>Cc1ccc2c(N3CC[C@@H](N)C3)nc(-c3c(O)cccc3F)nc2c1 -US20130252941A1,1,Clc1cc(Nc2nccc3nn(-c4c(Cl)cccc4Cl)cc23)ncn1.FC1CNC1>>FC1CN(c2cc(Nc3nccc4nn(-c5c(Cl)cccc5Cl)cc34)ncn2)C1 -US06503925B1,3,O=[N+]([O-])c1cc(I)ccc1F.OB(O)c1ccccc1>>O=[N+]([O-])c1cc(-c2ccccc2)ccc1F -US20120010247A1,1,CCI.OCc1ccc(O)c(Br)c1>>CCOc1ccc(CO)cc1Br -US20120214767A1,3,C=C[Sn](CCCC)(CCCC)CCCC.FC(F)(F)c1c(-c2ccccc2)noc1-c1nc2c(s1)-c1ccc(Br)cc1CC2>>C=Cc1ccc2c(c1)CCc1nc(-c3onc(-c4ccccc4)c3C(F)(F)F)sc1-2 -US08569306B2,6,CCOC(=O)C1CCC(Nc2nccc(-c3cnc4c(C(C)(C)O)cccn34)n2)CC1>>CC(C)(O)c1cccn2c(-c3ccnc(NC4CCC(C(=O)O)CC4)n3)cnc12 -US20060189625A1,6,COc1cc(F)c(N2CCN(C(=O)c3ccc(C(C)(C)C)cc3)CC2)cc1F>>CC(C)(C)c1ccc(C(=O)N2CCN(c3cc(F)c(O)cc3F)CC2)cc1 -US20050014812A1,1,COC(=O)c1ccccc1COc1cc(C)c2nc(C)[nH]c2c1.Clc1cc(-c2ccccc2)ccc1CBr>>COC(=O)c1ccccc1COc1cc(C)c2nc(C)n(Cc3ccc(-c4ccccc4)cc3Cl)c2c1 -US20140371450A1,2,Cc1cccc(Cl)c1C(=O)Cl.Nc1ccccc1>>Cc1cccc(Cl)c1C(=O)Nc1ccccc1 -US04023957,2,CNCC=O.CS(=O)(=O)c1nnc(N=C=O)s1>>CN(CC=O)C(=O)Nc1nnc(S(C)(=O)=O)s1 -US06071934,8,CSc1ccc(/C=C2/C(CCO)=C(C)c3ccccc32)cc1>>CSc1ccc(/C=C2/C(CC=O)=C(C)c3ccccc32)cc1 -US06342504B1,7,CC(C)(C)OC(=O)Cn1cccc([N+](=O)[O-])c1=O>>CC(C)(C)OC(=O)Cn1cccc(N)c1=O -US09067898B1,7,CCOC(=O)/C=C\c1cc(C(F)(F)F)c(OC)c(C(F)(F)F)c1>>CCOC(=O)CCc1cc(C(F)(F)F)c(OC)c(C(F)(F)F)c1 -US20020177594A1,2,CNC(=O)C(=O)CCCCCN.O=S(=O)(Cl)c1ccc(Cl)cc1>>CNC(=O)C(=O)CCCCCNS(=O)(=O)c1ccc(Cl)cc1 -US20140243283A1,6,Brc1ccc2c(c1)C1(CCC3(CC1)OCCO3)c1cc(Br)ccc1-2>>O=C1CCC2(CC1)c1cc(Br)ccc1-c1ccc(Br)cc12 -US20140364466A1,6,COC(=O)c1ccc(C2=NSC(C)(c3cc(Cl)cc(Cl)c3)C2)cc1C>>Cc1cc(C2=NSC(C)(c3cc(Cl)cc(Cl)c3)C2)ccc1C(=O)O -US05344843,6,COC(=O)C(=O)c1ccc(OCCOc2ccc(F)cc2)cc1>>O=C(O)C(=O)c1ccc(OCCOc2ccc(F)cc2)cc1 -US04001426,1,CN(C)CCCl.Cc1cc(C)cc(C(=O)c2c(-c3ccc(O)cc3)oc3ccccc23)c1>>Cc1cc(C)cc(C(=O)c2c(-c3ccc(OCCN(C)C)cc3)oc3ccccc23)c1 -US08329682B2,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2.O=C1Cc2c(cccc2-c2cccc(F)c2F)N1>>Cc1c(/C=C2\C(=O)Nc3cccc(-c4cccc(F)c4F)c32)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2 -US20090298878A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Fc1ccc2[nH]c(CCl)nc2c1>>CC(C)(C)OC(=O)n1c(CCl)nc2cc(F)ccc21 -US20080312226A1,2,S=C=Nc1cccnc1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>S=C(Nc1cccnc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 -US08143263B2,6,CCCCC(O[Si](C)(C)C(C)(C)C)C(=O)Nc1ccc(C)cn1>>CCCCC(O)C(=O)Nc1ccc(C)cn1 -US07235548B2,7,CC(=O)c1ccc(N)c(S(N)(=O)=O)c1>>CC(O)c1ccc(N)c(S(N)(=O)=O)c1 -US20070027173A1,2,O=C1OC2(CCN(C(=O)c3c[nH]c4cc(Cl)ccc34)CC2)c2ccc(F)cc21.O=S(=O)(Cl)c1cc(F)cc(F)c1>>O=C1OC2(CCN(C(=O)c3cn(S(=O)(=O)c4cc(F)cc(F)c4)c4cc(Cl)ccc34)CC2)c2ccc(F)cc21 -US20150175561A1,9,C#CC[C@H](NC(=O)OC(C)(C)C)C(N)=O>>C#CC[C@@H](C#N)NC(=O)OC(C)(C)C -US20130345123A1,2,N[C@H]1CCS[C@H]2CC[C@@H](C(F)(F)F)CN2C1=O.O=C(O)[C@H](CC[C@H](Cc1ccccc1)C(=O)N[C@@H]1CCCCN(c2ccccc2)C1=O)Cc1ccccc1>>O=C(N[C@H]1CCCCN(c2ccccc2)C1=O)[C@H](CC[C@H](Cc1ccccc1)C(=O)N[C@H]1CCS[C@H]2CC[C@@H](C(F)(F)F)CN2C1=O)Cc1ccccc1 -US20130190289A1,1,CN1CCC(N)CC1=O.COC(=O)c1sc(C#CC(C)(C)C)cc1Br>>COC(=O)c1sc(C#CC(C)(C)C)cc1NC1CCN(C)C(=O)C1 -US20060058264A1,2,COC(=O)[C@@H]1C[C@H](N)C(=O)[C@@H]2[C@@]3(C)C[C@@H](c4ccoc4)OC(=O)[C@@H]3CC[C@]21C.CS(=O)(=O)Cl>>COC(=O)[C@@H]1C[C@H](NS(C)(=O)=O)C(=O)[C@@H]2[C@@]3(C)C[C@@H](c4ccoc4)OC(=O)[C@@H]3CC[C@]21C -US20150148313A1,2,Cc1cc(Br)ccc1CC(=O)O.O=C1N[C@@H](Cc2ccccc2)CO1>>Cc1cc(Br)ccc1CC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1 -US08084620B2,1,CC(C)(CCO)C(=O)Nc1ccc2c(c1)[nH]c1c(C(N)=O)ccc(Br)c12>>CC1(C)CCN(c2ccc3c(c2)[nH]c2c(C(N)=O)ccc(Br)c23)C1=O -US07888464B2,2,COC(=O)[C@@H](N)C(C)(C)C.O=C(F)OC12CC3CC(CC(C3)C1)C2>>COC(=O)[C@@H](NC(=O)OC12CC3CC(CC(C3)C1)C2)C(C)(C)C -US08049015B2,2,CCNCc1cc(C(F)(F)F)ccc1-c1cncc(CC(=O)OCC)c1.CCOc1cc(OCC)nc(CC(=O)O)n1>>CCOC(=O)Cc1cncc(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)Cc2nc(OCC)cc(OCC)n2)c1 -US08563746B2,3,C#Cc1ccccc1.C[Si](C)(C)CCOCn1c(S(C)(=O)=O)nc2cc(I)c(Cl)cc21>>C[Si](C)(C)CCOCn1c(S(C)(=O)=O)nc2cc(C#Cc3ccccc3)c(Cl)cc21 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CCCCCC(O)c3ccccc3F)CC2)c1.Oc1ccc(F)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCCC(Oc3ccc(F)cc3)c3ccccc3F)CC2)c1 -US05234946,3,CCCC[Sn](CCCC)(CCCC)c1ccsc1.CCOC(=O)c1csc(Br)c1>>CCOC(=O)c1csc(-c2ccsc2)c1 -US20020198194A1,1,Cc1cc(Cl)c2ccc(OCc3ccc(C#N)cc3)cc2n1.O[C@H]1CCNC1>>Cc1cc(N2CC[C@H](O)C2)c2ccc(OCc3ccc(C#N)cc3)cc2n1 -US08557805B2,1,CS(=O)(=O)c1ccc(O)cn1.O=[N+]([O-])c1ccc(F)cc1>>CS(=O)(=O)c1ccc(Oc2ccc([N+](=O)[O-])cc2)cn1 -US20110207704A1,7,CCOC(=O)/C(C)=C/[C@@H](C)Oc1ccc(-c2nc(-c3ccc(OC(C)C)c(C(F)(F)F)c3)no2)cc1>>CCOC(=O)C(C)C[C@@H](C)Oc1ccc(-c2nc(-c3ccc(OC(C)C)c(C(F)(F)F)c3)no2)cc1 -US08809538B2,6,COC(=O)c1sc(NC(=O)OC(C)(C)C)c(C#N)c1C>>Cc1c(C(=O)O)sc(NC(=O)OC(C)(C)C)c1C#N -US08530670B2,1,C1COCCN1.O=C1C=C(O)C(c2ccc(N3CCOCC3)cc2)N1c1ccc2[nH]cnc2c1>>O=C1C=C(N2CCOCC2)C(c2ccc(N3CCOCC3)cc2)N1c1ccc2[nH]cnc2c1 -US06809097B1,1,COc1cc2nccc(Cl)c2cc1OC.Oc1cccc(O)c1>>COc1cc2nccc(Oc3cccc(O)c3)c2cc1OC -US20090221555A1,1,CNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.COc1ccc2c(c1N)C(=O)N(C)CCC2>>CNC(=O)c1ccccc1Nc1nc(Nc2c(OC)ccc3c2C(=O)N(C)CCC3)ncc1Cl -US07452889B2,1,Cc1nc2cc(OCC(O)CN3CCNCC3)ccc2s1.O=C1C(Cl)CCN1c1ccccc1>>Cc1nc2cc(OC[C@H](O)CN3CCN(C4CCN(c5ccccc5)C4=O)CC3)ccc2s1 -US08124617B2,1,COC(=O)c1cc(O)cc([N+](=O)[O-])c1.Fc1ccccc1CBr>>COC(=O)c1cc(OCc2ccccc2F)cc([N+](=O)[O-])c1 -US20140243306A1,6,CC(C)(C)OC(=O)N1CC=C(c2cc3c(Cl)ncnc3[nH]2)CC1>>Clc1ncnc2[nH]c(C3=CCNCC3)cc12 -US08168642B2,6,CCOC(=O)C1=C(C)NC(c2csc(NC(C)=O)n2)=NC1c1ccc(F)cc1Cl>>CCOC(=O)C1=C(C)NC(c2csc(N)n2)=NC1c1ccc(F)cc1Cl -US20100158863A1,1,ClCCCBr.Oc1ccc(Br)cc1F>>Fc1cc(Br)ccc1OCCCCl -US20150094296A1,7,O=[N+]([O-])c1cnn(C2(CO)CCC2)c1>>Nc1cnn(C2(CO)CCC2)c1 -US05610195,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(N)CCO>>CC(CCO)NC(=O)OC(C)(C)C -US20140349994A1,1,COc1ccc(Cn2ncc(C(=O)N(C)OC)c2Br)cc1.NCc1ccccc1>>COc1ccc(Cn2ncc(C(=O)N(C)OC)c2NCc2ccccc2)cc1 -US06372759B1,2,Nc1ccccc1NC(=O)OCC1CCN(c2ccncc2)CC1.O=C(O)c1ccc2c(Br)c[nH]c2c1>>O=C(Nc1ccccc1NC(=O)c1ccc2c(Br)c[nH]c2c1)OCC1CCN(c2ccncc2)CC1 -US20030144326A1,1,CS(=O)(=O)Nc1cc([C@@H](O)CN)ccc1O.O=C1CCN(c2ccc(NS(=O)(=O)c3cccnc3)cc2)CC1>>CS(=O)(=O)Nc1cc([C@@H](O)CNC2CCN(c3ccc(NS(=O)(=O)c4cccnc4)cc3)CC2)ccc1O -US20150252044A1,2,C1CNCCN1.O=C(O)c1ccc2cncc(-c3ccc(Cl)cc3)c2n1>>O=C(c1ccc2cncc(-c3ccc(Cl)cc3)c2n1)N1CCNCC1 -US08008325B2,2,COC(=O)C(OP(=O)(O)[C@@H](N)C(C)C)c1cccc(NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)c1.O=S(=O)(Cl)Cc1ccccc1>>COC(=O)C(OP(=O)(O)[C@@H](NS(=O)(=O)Cc1ccccc1)C(C)C)c1cccc(NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)c1 -US20020156311A1,1,C=CCOc1ccc(C=O)cc1.Cc1c(N)cccc1[N+](=O)[O-]>>C=CCOc1ccc(CNc2cccc([N+](=O)[O-])c2C)cc1 -US07015218B1,2,N#Cc1cc([N+](=O)[O-])ccc1N1CCC(O)CC1.O=C(Cl)c1ccccc1>>N#Cc1cc([N+](=O)[O-])ccc1N1CCC(OC(=O)c2ccccc2)CC1 -US07728029B2,6,CCOC(=O)c1cnn(C(C)(C)C)c1-c1cc(Cl)on1>>CC(C)(C)n1ncc(C(=O)O)c1-c1cc(Cl)on1 -US08088930B2,1,Fc1cc2nc(-c3ccc(Cl)cc3)n(C(CBr)C3CCCCC3)c2cc1F.Oc1cccnc1>>Fc1cc2nc(-c3ccc(Cl)cc3)n(C(COc3cccnc3)C3CCCCC3)c2cc1F -US06127398,1,BrC1CCCC1.CCc1n[nH]c2cc(Br)ccc12>>CCc1nn(C2CCCC2)c2cc(Br)ccc12 -US06207693B1,1,O=[N+]([O-])c1cccc2[nH]c(Cl)nc12.c1c[nH]cn1>>O=[N+]([O-])c1cccc2[nH]c(-n3ccnc3)nc12 -US20140303149A1,6,COc1cc(NC(C)=O)ccc1[N+](=O)[O-]>>COc1cc(N)ccc1[N+](=O)[O-] -US06043243,2,CC(C)=CCC/C(C)=C/COc1ccccc1C(=O)O.CCN1CCCC1CN>>CCN1CCCC1CNC(=O)c1ccccc1OC/C=C(\C)CCC=C(C)C -US20150274695A1,3,COc1cc(F)ccc1B(O)O.Clc1cc(Cl)ncn1>>COc1cc(F)ccc1-c1cc(Cl)ncn1 -US20120015907A1,8,CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(N(CCCCO)S(C)(=O)=O)c(I)cc12>>CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(N(CCCC=O)S(C)(=O)=O)c(I)cc12 -US20040121965A1,3,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)(C)c1cccc(Br)c1)C(C)(C)C.OB(O)c1ccccc1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)(C)c1cccc(-c2ccccc2)c1)C(C)(C)C -US20040121965A1,3,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)(C)c1cccc(Br)c1)C(C)(C)C.OB(O)c1ccccc1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](NC)C(C)(C)c1cccc(-c2ccccc2)c1)C(C)(C)C -US08445679B2,7,O=C(c1ccc([N+](=O)[O-])c(C(F)(F)F)c1)N1CCOCC1>>Nc1ccc(C(=O)N2CCOCC2)cc1C(F)(F)F -US20030069392A1,7,CCCCCCCCCCCCCCNC(=O)CCCCCCCCCCCCC>>CCCCCCCCCCCCCCNCCCCCCCCCCCCCC -US05459151,6,CCOC(=O)C(=O)N1CCC(c2ccc(OC)c(OC3CCCC3)c2)CC1>>COc1ccc(C2CCN(C(=O)C(=O)O)CC2)cc1OC1CCCC1 -US08288419B2,2,CC(F)(F)c1ccc(Cn2cc(N)cn2)o1.COc1cccc(-c2oc(C)nc2C(=O)O)c1>>COc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3ccc(C(C)(F)F)o3)c2)c1 -US20040063720A1,1,N#Cc1cnc(Nc2cc(N3CCNCC3)ncn2)s1.O=C(CBr)NC1CC1>>N#Cc1cnc(Nc2cc(N3CCN(CC(=O)NC4CC4)CC3)ncn2)s1 -US20120029023A1,1,COCc1ccc(-c2cc(Cc3ccc(O)cc3)no2)c(N)n1.ClCc1ccccn1>>COCc1ccc(-c2cc(Cc3ccc(OCc4ccccn4)cc3)no2)c(N)n1 -US07704994B2,6,CC(C)(C)OC(=O)N1CCc2ccc(Oc3ccc(I)cc3F)cc2CC1>>Fc1cc(I)ccc1Oc1ccc2c(c1)CCNCC2 -US20050261315A1,2,CC(C)(C)c1cc(N)on1.O=C(O)Cc1ccc(OCc2ccccc2)cc1>>CC(C)(C)c1cc(NC(=O)Cc2ccc(OCc3ccccc3)cc2)on1 -US20070124152A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCS(C)(=O)=O)c1=O.COCCN>>COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCS(C)(=O)=O)c1=O -US06787543B2,3,CON(C)C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1.C[Mg+]>>CC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 -US04490392,6,COc1ccc(CC(C)NCC(O)c2ccccc2OCc2ccccc2)c(OC)c1OC>>COc1ccc(CC(C)NCC(O)c2ccccc2O)c(OC)c1OC -US20130109649A1,3,COc1ncc(Br)cc1Cl.Cc1cc(C(=O)OC(C)(C)C)ccc1B1OC(C)(C)C(C)(C)O1>>COc1ncc(-c2ccc(C(=O)OC(C)(C)C)cc2C)cc1Cl -US20090186870A1,1,CCNCC.O=C(NC(=O)c1cc(-n2cccn2)ccc1Cl)Nc1nc2ccc(S(=O)(=O)CCCI)cc2s1>>CCN(CC)CCCS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(-n4cccn4)ccc3Cl)sc2c1 -US08153805B2,3,Cc1cc(Br)cc(C)c1C(=O)N1CCC(N2CCC(O)CC2)CC1.OB(O)c1ccc(OC(F)(F)F)cc1>>Cc1cc(-c2ccc(OC(F)(F)F)cc2)cc(C)c1C(=O)N1CCC(N2CCC(O)CC2)CC1 -US20120232278A1,6,COC(=O)c1ccc(N2CCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1[N+](=O)[O-]>>O=C(O)c1ccc(N2CCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1[N+](=O)[O-] -US20080269210A1,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.OC1(c2cc3nc(Cl)nc(N4CCOCC4)c3s2)CCN(Cc2ccccn2)CC1>>Nc1ncc(-c2nc(N3CCOCC3)c3sc(C4(O)CCN(Cc5ccccn5)CC4)cc3n2)cn1 -US09050344B2,3,CC1(O)CN(c2ccc(Br)c([C@H](Cc3cc(F)cc(F)c3)NC(=O)Cn3nc(C(F)F)c4c3C(F)(F)[C@@H]3C[C@H]43)n2)C1.Cn1nc(NS(C)(=O)=O)c2cccc(B3OC(C)(C)C(C)(C)O3)c21>>Cn1nc(NS(C)(=O)=O)c2cccc(-c3ccc(N4CC(C)(O)C4)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)Cn3nc(C(F)F)c4c3C(F)(F)[C@@H]3C[C@H]43)c21 -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.Cc1cccc(B(O)O)c1>>COc1ccc2c(-c3cccc(C)c3)nc(Nc3cc(C)[nH]n3)cc2c1 -US20130331374A1,1,CC1(C)CC(Nc2nc(Cl)ncc2F)CC2CCC(=O)N21.Cn1nnn(-c2cc(N)c(F)cc2C2CC2)c1=O>>Cn1nnn(-c2cc(Nc3ncc(F)c(NC4CC5CCC(=O)N5C(C)(C)C4)n3)c(F)cc2C2CC2)c1=O -US20100120775A1,6,COC(=O)c1ccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CCCC4)cc3)ccc2n1>>O=C(O)c1ccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CCCC4)cc3)ccc2n1 -US08455477B2,3,C#CC1CC1.Cn1cc(-c2cc(OCc3cccnc3)c3c(I)cnn3c2)cn1>>Cn1cc(-c2cc(OCc3cccnc3)c3c(C#CC4CC4)cnn3c2)cn1 -US20100256092A1,1,O=Cc1ccc(F)cc1Br.O=[N+]([O-])c1cccc(O)c1>>O=Cc1ccc(Oc2cccc([N+](=O)[O-])c2)cc1Br -US20090306076A1,1,CC(C)CN.O=Cc1ccc2c(c1)OCCCC2>>CC(C)CNCc1ccc2c(c1)OCCCC2 -US20150094281A1,6,C[C@H](O)[C@H](OCc1ccccc1)[C@H](CCC[C@H](NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1)Cc1ccc(F)cc1F>>C[C@H](O)[C@H](OCc1ccccc1)[C@H](CCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)Cc1ccc(F)cc1F -US06413995B1,3,CCOC(=O)CBr.COCOc1ccc(C(=O)c2ccccc2)cc1>>CCOC(=O)CC(O)(c1ccccc1)c1ccc(OCOC)cc1 -US05308857,2,COC(=O)c1ccc(-c2csc(N=C(N)N)n2)o1.NN>>NNC(=O)c1ccc(-c2csc(N=C(N)N)n2)o1 -US20150284386A1,7,CC1(C)C(=O)Nc2cc([N+](=O)[O-])ccc21>>CC1(C)C(=O)Nc2cc(N)ccc21 -US05432194,6,CC(C)(C)OC(=O)Nc1cccc(C2(O)CCOCC2)c1>>Nc1cccc(C2(O)CCOCC2)c1 -US07179801B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1ncc(CCCN)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cn1ncc(CCCNC(=O)OC(C)(C)C)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20100240638A1,2,C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)c1ccccc1NC(=O)CCCCCCCC(=O)OC.CC(C)(C)OC(=O)N1C[C@H](OC(=O)N2Cc3cccc(F)c3C2)C[C@H]1C(=O)O>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(F)c3C2)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1NC(=O)CCCCCCCC(=O)OC -US07741323B2,1,O=C([O-])C1=C(c2ccccc2)c2ccc(O)cc2C1=O.OCCN1CCOCC1>>O=C([O-])C1=C(c2ccccc2)c2ccc(OCCN3CCOCC3)cc2C1=O -US20090105217A1,2,CCOc1cc([N+](=O)[O-])ccc1C(=O)NN.S=C=NCCCN1CCCCC1>>CCOc1cc([N+](=O)[O-])ccc1C(=O)NNC(=S)NCCCN1CCCCC1 -US20140058098A1,9,CC(C)n1ncnc1-c1cn2c(n1)-c1cc(Cl)ncc1OCC2>>CC(C)n1ncnc1-c1cn2c(n1)-c1ccncc1OCC2 -US20090118274A1,6,CS(=O)(=O)N1CCc2c(c(-c3ccc(Cl)c(C#N)c3)nn2CCC2OCCO2)C1>>CS(=O)(=O)N1CCc2c(c(-c3ccc(Cl)c(C#N)c3)nn2CCC=O)C1 -US05246915,1,COC(=O)CBr.COc1ccc2c(c1)C(N)CCC2>>COC(=O)CNC1CCCc2ccc(OC)cc21 -US20090181966A1,1,CCN(CC)c1ccc2c(c1)N(C(=O)c1ccc(N(C)C)cc1)[C@@H](C)C[C@H]2N(C(C)=O)c1ccc(Cl)cc1.CCNCC>>CCN(CC)c1ccc(N(C(C)=O)[C@@H]2C[C@H](C)N(C(=O)c3ccc(N(C)C)cc3)c3cc(N(CC)CC)ccc32)cc1 -US20100168080A1,6,CC(C)(C)OC(=O)N1CCC(O)(Cc2ccc(Cl)cc2)C1>>OC1(Cc2ccc(Cl)cc2)CCNC1 -US20070004774A1,6,COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CC(CCOCc2ccccc2)N(C(=O)C(F)(F)F)c2ccc(C(F)(F)F)cc21>>COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CC(CCOCc2ccccc2)Nc2ccc(C(F)(F)F)cc21 -US06248740B1,1,CCOC(=O)c1c(C)nc2ccc(Cl)nn12.NCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>CCOC(=O)c1c(C)nc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn12 -US06340759B1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(C2(CCOC(C)=O)CCOCC2)cc1.CCN1CCN(c2nc(Br)cc3ccccc23)CC1>>CCN1CCN(c2nc(-c3ccc(C4(CCOC(C)=O)CCOCC4)cc3)cc3ccccc23)CC1 -US04558043,9,OC1Cc2cc(Cl)c(N3CCCCC3)cc2O1>>Clc1cc2c(cc1N1CCCCC1)OCC2 -US20140275016A1,7,Cc1nc([N+](=O)[O-])ccc1Oc1ccnc(NC(=O)OC(C)(C)C)c1>>Cc1nc(N)ccc1Oc1ccnc(NC(=O)OC(C)(C)C)c1 -US07754759B2,6,CC(=O)O[C@H](C)C(=O)NCC1CCc2ccc(S(=O)(=O)c3ccccc3)cc2O1>>C[C@@H](O)C(=O)NC[C@H]1CCc2ccc(S(=O)(=O)c3ccccc3)cc2O1 -US20120277220A1,6,CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3c(F)cc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3OC)nc21>>CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3c(F)cc(N4CCNCC4)cc3OC)nc21 -US07875726B2,2,Nc1ccccc1.O=C(O)CCl>>O=C(CCl)Nc1ccccc1 -US04446141,2,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1.CCOC(=O)Cl>>CCOC(=O)n1c(=O)n(C2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21 -US20060173004A1,6,COC(=O)/C=C/c1ccc2ccccc2c1[N+](=O)[O-]>>O=C(O)/C=C/c1ccc2ccccc2c1[N+](=O)[O-] -US20090105252A1,1,C1COCCN1.CS(=O)(=O)c1cc(Br)ccc1C=O>>CS(=O)(=O)c1cc(Br)ccc1CN1CCOCC1 -US07718801B2,1,C[C@H](NC(=O)OC(C)(C)C)c1cccc(OS(=O)(=O)C(F)(F)F)c1.O=C(N1CCNCC1)C(F)(F)F>>C[C@H](NC(=O)OC(C)(C)C)c1cccc(N2CCN(C(=O)C(F)(F)F)CC2)c1 -US04182762,1,NN1CCNC(=O)C1=O.O=Cc1ccc(Br)o1>>O=C1NCCN(N=Cc2ccc(Br)o2)C1=O -US20060089393A1,9,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(-c2nnc(CCl)o2)cc1.[N-]=[N+]=[N-]>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(-c2nnc(CN=[N+]=[N-])o2)cc1 -US20150210697A1,6,COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCC5(CCN(C)C5=O)CC4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>CN1CCC2(CCN(c3cc(C#N)cc(Nc4nc(NC5CC5)c5ncc(C#N)n5n4)c3Cl)CC2)C1=O -US08541457B2,1,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=Cc1ccccc1>>Cc1nc(NCc2ccccc2)sc1C(=O)NCc1ccccc1 -US20120329818A1,2,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.Nc1cccc(-c2cnco2)c1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cccc(-c3cnco3)c2)CC1 -US20010031763A1,5,COc1ccc2nc3cc(Cl)ccc3c(NCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2nc3cc(Cl)ccc3c(NCCN(C(=O)C(F)(F)F)c3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 -US07863450B2,2,CC(C)(N)CO.O=C(O)c1ccc(OCc2ccccc2)cc1>>CC(C)(CO)NC(=O)c1ccc(OCc2ccccc2)cc1 -US08481542B2,6,COC(=O)c1cnc(N2CCN(c3nnc(Cc4ccccc4)c(C)c3C)C[C@H]2C)cn1>>Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(=O)O)cn3)[C@H](C)C2)c1C -US20100249163A1,1,COCCCc1cc(C=O)cc(OCCOC)c1.NC1CC1>>COCCCc1cc(CNC2CC2)cc(OCCOC)c1 -US20080275027A1,1,CC(C)(C)OC(=O)N1CCN(c2ccc(O)cc2)C(=O)C1.ClCCCBr>>CC(C)(C)OC(=O)N1CCN(c2ccc(OCCCCl)cc2)C(=O)C1 -US20100120785A1,6,CC(C)(C)OC(=O)N1CCN(c2nccnc2-c2ccccc2C(F)(F)F)CC1>>FC(F)(F)c1ccccc1-c1nccnc1N1CCNCC1 -US20100004271A1,2,COC(=O)CN.O=C(O)c1cc(Br)c(Oc2ccc([N+](=O)[O-])cc2)c(Br)c1>>COC(=O)CNC(=O)c1cc(Br)c(Oc2ccc([N+](=O)[O-])cc2)c(Br)c1 -US07361672B2,2,Nc1nc(CC(=O)N2CCN(CC(=O)N3CCCC3)CC2)cs1.O=C(O)c1ccc2c(c1)OCO2>>O=C(Nc1nc(CC(=O)N2CCN(CC(=O)N3CCCC3)CC2)cs1)c1ccc2c(c1)OCO2 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CCCc1ccncc1Br>>CCCc1ccncc1C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C -US20020107252A1,2,COc1ccc(-c2cc(N)c(C(N)=O)s2)cc1.C[Si](C)(C)N=C=O>>COc1ccc(-c2cc(NC(N)=O)c(C(N)=O)s2)cc1 -US20120295897A1,1,CCOC(=O)c1cc(CBr)oc1C(F)(F)F.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCO3>>CCOC(=O)c1cc(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)oc1C(F)(F)F -US20080058311A1,6,CC(C)(C)NC(=O)C(CO[Si](C)(C)C(C)(C)C)NC(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1>>CC(C)(C)NC(=O)C(CO)NC(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1 -US04657915,1,Cc1ncc[nH]1.O=c1ccc2c(Br)nccc2[nH]1>>Cc1nccn1-c1nccc2[nH]c(=O)ccc12 -US06479554B2,3,CCOP(=O)(CC#N)OCC.COc1cc(OC)cc(C(=O)c2ccc(OC)c(OC)c2)c1>>COc1cc(OC)cc(C(=CC#N)c2ccc(OC)c(OC)c2)c1 -US08524743B2,1,C#CCBr.O=C(Cn1nc(C(F)F)cc1C(F)F)N1CCC(c2nc(C3=NOC(c4ccccc4O)C3)cs2)CC1>>C#CCOc1ccccc1C1CC(c2csc(C3CCN(C(=O)Cn4nc(C(F)F)cc4C(F)F)CC3)n2)=NO1 -US20080119518A1,6,CNC(=O)c1ccc2ccn(C3CCN(C(=O)OCc4ccccc4)CC3)c2c1>>CNC(=O)c1ccc2ccn(C3CCNCC3)c2c1 -US20040266839A1,1,CCI.Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCc4ccccc4Cl)cc3)c2)o1>>CCN(Cc1ccccc1Cl)C(=O)c1ccc(-c2cc(-c3nnc(C)o3)ccc2C)cc1 -US04791213,1,C[N+](C)(C)CC(O)CCl.O=c1c2ccccc2sc2ccc(O)cc12>>C[N+](C)(C)CC(O)COc1ccc2sc3ccccc3c(=O)c2c1 -US07160891B2,1,Fc1cccc2ncnc(Nc3c(Cl)ccc4c3OCO4)c12.Oc1ccccc1>>Clc1ccc2c(c1Nc1ncnc3cccc(Oc4ccccc4)c13)OCO2 -US09079866B2,3,Nc1cnc(-c2ccc(Br)cc2F)cn1.OB(O)c1cccnc1N1CCCC1>>Nc1cnc(-c2ccc(-c3cccnc3N3CCCC3)cc2F)cn1 -US05710314,1,COC(=O)Cc1ccccc1CBr.Cc1ccccc1O>>COC(=O)Cc1ccccc1COc1ccccc1C -US20080114005A1,1,BrCc1ccccc1.Oc1cccc(O)c1>>Oc1cccc(OCc2ccccc2)c1 -US20150166523A1,1,CCOC(=O)c1cc[nH]n1.Fc1ccc(F)nc1>>CCOC(=O)c1ccn(-c2ccc(F)cn2)n1 -US20030078277A1,1,Cc1cc(C)c(-c2c(C)nn3c(O)c(CCO)c(C)nc23)c(C)c1>>Cc1cc(C)c(-c2c(C)nn3c4c(c(C)nc23)CCO4)c(C)c1 -US08957070B2,2,CCOC(=O)c1cc2cc(OC)cc(N)c2[nH]1.O=S(=O)(Cl)c1cccs1>>CCOC(=O)c1cc2cc(OC)cc(NS(=O)(=O)c3cccs3)c2[nH]1 -US20110160207A1,2,Cc1ccc(C(=O)NC2CC2)cc1N.O=C(O)c1ccc(-c2ccc(Cl)cc2)o1>>Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(Cl)cc2)o1 -US07045545B1,3,Brc1cc2ccccc2o1.CON(C)C(=O)C1(NC(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)NC1(C(=O)c2cc3ccccc3o2)CC1 -US05541229,6,CCCCc1nc2cccc(OC)c2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2cccc(OC)c2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20100130492A1,2,O=C(O)C(F)(F)F.c1ccc(CN2CCNC3(CC3)C2)cc1>>O=C(N1CCN(Cc2ccccc2)CC12CC2)C(F)(F)F -US06358948B1,3,CC1Nc2ccc(Br)cc2C(C)(C)O1.Cc1cc(C#N)sc1Br>>Cc1cc(C#N)sc1-c1ccc2c(c1)C(C)(C)OC(C)N2 -US04397677,1,CCN.CCOC(CBr)OCC>>CCNCC(OCC)OCC -US08026255B2,1,CCOc1cc(C=O)ccc1C.N#Cc1ccnc(NC2CCNCC2)c1>>CCOc1cc(CN2CCC(Nc3cc(C#N)ccn3)CC2)ccc1C -US20140142083A1,1,CN1CCC(=O)CC1.COC(=O)c1cc(Br)cc(N)c1C>>COC(=O)c1cc(Br)cc(NC2CCN(C)CC2)c1C -US20100041698A1,7,COc1ccccc1CNC(=O)c1ccc([N+](=O)[O-])cc1N>>COc1ccccc1CNCc1ccc([N+](=O)[O-])cc1N -US05597845,1,COc1ccccc1CN(C)C(=O)[C@H](Cc1ccccc1)N(CC=O)C(=O)OC(C)(C)C.N[C@H](CC(=O)O)Cc1c[nH]c2ccccc12>>COc1ccccc1CN(C)C(=O)[C@H](Cc1ccccc1)N(CCN[C@H](CC(=O)O)Cc1c[nH]c2ccccc12)C(=O)OC(C)(C)C -US20150246919A1,1,Cc1cc(-c2nc3cnc(Cl)cc3n2C(C)c2ccccn2)cn(C)c1=O.OCC1CC1>>Cc1cc(-c2nc3cnc(OCC4CC4)cc3n2C(C)c2ccccn2)cn(C)c1=O -US08907094B2,1,Fc1ccc2nnc(Cl)n2c1.O[C@H]1CCCNC1>>O[C@H]1CCCN(c2nnc3ccc(F)cn23)C1 -US20130324506A1,3,Cc1c(I)nc2n1CCc1ccccc1C2OC1CCN(C)CC1.O=C(N[C@@H]1CC[C@@H](O)CC1)c1ccc(B(O)O)cc1>>Cc1c(-c2ccc(C(=O)NC3CCC(O)CC3)cc2)nc2n1CCc1ccccc1C2OC1CCN(C)CC1 -US05668157,7,CN(C)c1ncccc1[N+](=O)[O-]>>CN(C)c1ncccc1N -US20080027050A1,2,CCOC(=O)c1nc2scc(N)c2c(=O)[nH]1.O=C(Cl)Cc1ccccc1>>CCOC(=O)c1nc2scc(NC(=O)Cc3ccccc3)c2c(=O)[nH]1 -US20080009479A1,6,COC(=O)c1cnc(Oc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)cn1>>CC(C)(C)OC(=O)N1CCc2ccc(Oc3cnc(C(=O)O)cn3)cc2CC1 -US03997535,2,COc1ccc2nc(C(=O)O)c(OC)nc2c1.Nc1nnn[nH]1>>COc1ccc2nc(C(=O)Nc3nnn[nH]3)c(OC)nc2c1 -US06982348B2,7,CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(=O)c1ccc(Br)cc1>>CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(Br)cc1 -US05380749,2,CCN(CC)CCNc1ccc(CN)c2sc3ccccc3c(=O)c12.COc1ccc(S(=O)(=O)Cl)cc1>>CCN(CC)CCNc1ccc(CNS(=O)(=O)c2ccc(OC)cc2)c2sc3ccccc3c(=O)c12 -US07176224B2,1,CCOC(=O)C(C)Br.Oc1ccc(C2CCCCC2)cc1>>CCOC(=O)C(C)Oc1ccc(C2CCCCC2)cc1 -US20050059713A1,3,O=C(O)c1cc(Br)ccc1O.OB(O)c1ccc(F)c(Cl)c1>>O=C(O)c1cc(-c2ccc(F)c(Cl)c2)ccc1O -US05286728,2,CC(C)OCCN(C(=O)CCl)c1ccc(C(=O)Cl)cc1.Fc1ccc(CCN2CCNCC2)cc1>>CC(C)OCCN(C(=O)CCl)c1ccc(C(=O)N2CCN(CCc3ccc(F)cc3)CC2)cc1 -US08063061B2,1,CCOC(=O)c1cc(-c2ccc3c(c2)c2cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c2n3C)n[nH]1.CI>>CCOC(=O)c1cc(-c2ccc3c(c2)c2cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c2n3C)nn1C -US08674115B2,4,CC(=O)CCC(=O)c1ccnc(Cl)c1.NCC(=O)OCc1ccccc1>>Cc1ccc(-c2ccnc(Cl)c2)n1CC(=O)OCc1ccccc1 -US20130040930A1,2,COC(=O)c1ccc(CN2CCCS2(=O)=O)nc1.Cc1cnc(N2CCNCC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(CN4CCCS4(=O)=O)nc3)CC2)c(C)c1 -US20100160292A1,3,CCOC(=O)c1ccc(Nc2nc(Br)cn(C)c2=O)cc1.Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1B1OC(C)(C)C(C)(C)O1>>CCOC(=O)c1ccc(Nc2nc(-c3cccc(NC(=O)c4ccc(C(C)(C)C)cc4)c3C)cn(C)c2=O)cc1 -US20110263571A1,1,CI.Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4CO)nc3)CC2)c(C)c1>>COC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cn1 -US08211885B2,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(O)c1c(Cl)n(-c2ccccc2)c2ccccc12>>CC(C)(C)OC(=O)N1CCN(C(=O)c2c(Cl)n(-c3ccccc3)c3ccccc23)CC1 -US07452992B2,3,C=C[Mg+].O=C(CCCl)c1ccccc1>>C=CC(O)(CCCl)c1ccccc1 -US20130045962A1,6,c1ccc(CN2CCN3CCOC[C@H]3C2)cc1>>C1CN2CCOC[C@H]2CN1 -US20130267569A1,7,CC(C)(O)c1coc(Cn2ncc([N+](=O)[O-])n2)n1>>CC(C)(O)c1coc(Cn2ncc(N)n2)n1 -US20140275071A1,2,CS(=O)(=O)Cl.OCCCC(F)(F)F>>CS(=O)(=O)OCCCC(F)(F)F -US20080242683A1,6,CC(C)(C)OC(=O)NC[C@@H]1C[C@@H](OC(C)(C)C)CN1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC[C@@H]1C[C@@H](OC(C)(C)C)CN1 -US08580962B2,6,CC(C)(C)OC(=O)N1CC2(CC(C#Cc3cccc(O)c3)=NO2)C1>>Oc1cccc(C#CC2=NOC3(CNC3)C2)c1 -US20010006969A1,1,C=CCN.Cc1csc2c(NC(C)C)nc(Cl)nc12>>C=CCNc1nc(NC(C)C)c2scc(C)c2n1 -US20110172414A1,1,Clc1cc(I)ccc1CBr.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1ccc(I)cc1Cl -US20080269210A1,6,CC(C)(C)OC(=O)NCC(=O)Nc1cccc(-c2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)c1>>NCC(=O)Nc1cccc(-c2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)c1 -US05344812,6,COc1ccc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)cc1>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(O)cc2)c1=O -US20150266916A1,3,COc1ccc(Cc2cc([C@]34OC[C@](C=O)(O3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]4OCc3ccccc3)ccc2Cl)c(F)c1F.C[Mg+]>>COc1ccc(Cc2cc([C@]34OC[C@](C(C)O)(O3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]4OCc3ccccc3)ccc2Cl)c(F)c1F -US20090156642A1,3,CN(Cc1cc(Br)c(S(=O)(=O)c2cccc(F)c2)s1)C(=O)OC(C)(C)C.OB(O)c1cccnc1F>>CN(Cc1cc(-c2cccnc2F)c(S(=O)(=O)c2cccc(F)c2)s1)C(=O)OC(C)(C)C -US20150284391A1,1,COc1cc2nc(F)cc(F)c2cc1F.C[O-]>>COc1cc(F)c2cc(F)c(OC)cc2n1 -US20100190764A1,6,CCOC(=O)C1(C)CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1>>CC1(C(=O)O)CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1 -US05750550,1,CC(C)c1cc(O)cc2c1C(=O)N(COc1cc(C(F)(F)F)nn1-c1ccc(Cl)cc1)S2(=O)=O.O=C(CCCO)OCc1ccccc1>>CC(C)c1cc(OCCCC(=O)OCc2ccccc2)cc2c1C(=O)N(COc1cc(C(F)(F)F)nn1-c1ccc(Cl)cc1)S2(=O)=O -US06790977B2,6,COc1cc(C#N)ccc1O>>N#Cc1ccc(O)c(O)c1 -US20110212945A1,6,Cc1ccc(Nc2cnc(-c3cccc(OC4CC4)c3)c(C)c2)c(C(=O)OC(C)(C)C)c1>>Cc1ccc(Nc2cnc(-c3cccc(OC4CC4)c3)c(C)c2)c(C(=O)O)c1 -US04265890,2,COC(CN)OC.COc1ccc(CC(=O)O)cc1OC>>COc1ccc(CC(=O)NCC(OC)OC)cc1OC -US04145347,2,CCOC(=O)C(C)N1CCCC1=O.C[C@H]1CCC[C@@H](C)N1CCN>>CC(C(=O)NCCN1[C@@H](C)CCC[C@H]1C)N1CCCC1=O -US08993582B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ncnc2[nH]ccc12>>CC(C)(C)OC(=O)n1ccc2c(Cl)ncnc21 -US06987114B1,1,Cc1cc(C)cc(Oc2[nH]c(=O)[nH]c(=O)c2C(C)C)c1.ClCc1c2ccccc2cc2ccccc12>>Cc1cc(C)cc(Oc2c(C(C)C)c(=O)[nH]c(=O)n2Cc2c3ccccc3cc3ccccc23)c1 -US20020077356A1,2,CC(C)(CC(O)(C(=O)Nc1ccc2c(c1)COC2=O)C(F)(F)F)c1cc(F)ccc1N.CS(=O)(=O)Cl>>CC(C)(CC(O)(C(=O)Nc1ccc2c(c1)COC2=O)C(F)(F)F)c1cc(F)ccc1NS(C)(=O)=O -US20150080393A1,1,CCOC(=O)[C@@H]1CC2(CCNCC2)CN1C(=O)OCc1ccccc1.Nc1nc(Cl)cc(COc2ccc(Br)cc2)n1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(COc4ccc(Br)cc4)nc(N)n3)CC2)CN1C(=O)OCc1ccccc1 -US20150191419A1,2,CC(C)(C)O.O=C(O)c1ccc(CBr)cc1>>CC(C)(C)OC(=O)c1ccc(CBr)cc1 -US04627871,2,COC(C)(C)C(=O)O.Cc1cc(C)nc(Sc2ccc(N)cc2)n1>>COC(C)(C)C(=O)Nc1ccc(Sc2nc(C)cc(C)n2)cc1 -US20120029190A1,9,[N-]=[N+]=NC1CN(C(=O)OCc2ccccc2)CCCC1O>>NC1CN(C(=O)OCc2ccccc2)CCCC1O -US20130040930A1,2,COC(=O)c1ccc(N2CCCS2(=O)=O)nc1C.Cc1cnc(N2CCNCC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCS4(=O)=O)nc3C)CC2)c(C)c1 -US20150087645A1,2,CC(C)C[C@H]1CN(c2ccc(OC(F)F)c(OCC3CC3)c2)CCN1.O=C(O)Cc1c[nH]cn1>>CC(C)C[C@H]1CN(c2ccc(OC(F)F)c(OCC3CC3)c2)CCN1C(=O)Cc1c[nH]cn1 -US20090181965A1,4,Cc1cn(-c2ccc(NC(N)=S)cc2F)cn1.O=C1C(Br)CCCC1c1ccc(OC(F)(F)F)cc1>>Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccc(OC(F)(F)F)cc3)cc2F)cn1 -US20150087585A1,6,Cc1cnn(C2(C(=O)OC(C)(C)C)CC2)c1>>Cc1cnn(C2(C(=O)O)CC2)c1 -US20140356322A1,2,COC(=O)CCC(=O)O.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C)NC(=O)[C@@H](N)CC(C)C)cc1>>COC(=O)CCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1 -US20140135316A1,7,COC(=O)CC(=O)N(Cc1ccccc1)c1ccccc1[N+](=O)[O-]>>COC(=O)CC(=O)N(Cc1ccccc1)c1ccccc1N -US06605620B1,1,COc1cc(-c2cc(CCl)ccn2)cc(OC)c1OC.COc1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>COc1ccc(N(Cc2ccnc(-c3cc(OC)c(OC)c(OC)c3)c2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20130196971A1,3,CC1(C)OB(c2ccc3occc3c2)OC1(C)C.O=C(C1CC1)N1CC[C@@H](Cn2nnnc2-c2ccc(Br)cc2)C1>>O=C(C1CC1)N1CC[C@@H](Cn2nnnc2-c2ccc(-c3ccc4occc4c3)cc2)C1 -US20140070204A1,1,Clc1ccc2c(c1)[nH]c1ccccc12.Ic1ccccc1>>Clc1ccc2c3ccccc3n(-c3ccccc3)c2c1 -US20150111914A1,2,C=C(C(=O)O)C(C)c1ccc(C(=O)OC)cc1.Nc1c(Br)ccc[n+]1[O-]>>C=C(C(=O)Nc1c(Br)ccc[n+]1[O-])C(C)c1ccc(C(=O)OC)cc1 -US04150035,7,NC(=O)NC1CCCC(=O)c2sccc21>>NC(=O)N[C@@H]1CCC[C@@H](O)c2sccc21 -US06403601B1,2,CNC[C@@H](CCN1CCC(c2ccccc2[S@](C)=O)CC1)c1ccc(Cl)c(Cl)c1.O=C(Cl)c1ccc([N+](=O)[O-])c2c1CCCC2>>CN(C[C@@H](CCN1CCC(c2ccccc2[S@](C)=O)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccc([N+](=O)[O-])c2c1CCCC2 -US05981559,4,CC(C)(C)c1csc(CCc2cccc(C(=O)Nc3cc(CCCS(=O)(=O)c4ccc(Cl)cc4)ccc3OCC#N)c2)n1.[N-]=[N+]=[N-]>>CC(C)(C)c1csc(CCc2cccc(C(=O)Nc3cc(CCCS(=O)(=O)c4ccc(Cl)cc4)ccc3OCc3nnn[nH]3)c2)n1 -US20120088746A1,2,Cc1cc([C@@H](C)N)c(F)cc1NS(C)(=O)=O.O=C(O)c1ccc2nc(C(F)(F)F)cc(N3CCC[C@H]3CO)c2c1>>Cc1cc([C@@H](C)NC(=O)c2ccc3nc(C(F)(F)F)cc(N4CCC[C@H]4CO)c3c2)c(F)cc1NS(C)(=O)=O -US05286725,1,CI.OCC1CCC(CO)CC1>>COCC1CCC(CO)CC1 -US20090143599A1,3,Brc1cscc1Br.C#CCCCCCC>>CCCCCCC#Cc1cscc1Br -US20050215626A1,7,COC(=O)c1ccc([N+](=O)[O-])cc1NC(=O)c1ccc(C(C)(C)C)cc1>>COC(=O)c1ccc(N)cc1NC(=O)c1ccc(C(C)(C)C)cc1 -US20040077656A1,1,COc1ccc2nccc([C@@H](O)CN3CCNCC3)c2c1.O=C(NCCBr)OCc1ccccc1>>COc1ccc2nccc([C@@H](O)CN3CCN(CCNC(=O)OCc4ccccc4)CC3)c2c1 -US04540692,2,COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C.Nc1ccc(O)c(=O)cc1>>CN1C(C(=O)Nc2ccc(O)c(=O)cc2)=C(O)c2ccccc2S1(=O)=O -US05272134,8,C[C@@]12C=CC[C@H]1[C@@H]1CCC3=CC(O)CC[C@]3(CO)[C@H]1CC2>>C[C@@]12C=CC[C@H]1[C@@H]1CCC3=CC(=O)CC[C@]3(CO)[C@H]1CC2 -US05919777,2,COC(=O)[C@@H](Cc1ccccc1)NCCN>>O=C1NCCN[C@@H]1Cc1ccccc1 -US20080039437A1,2,CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1C(F)F.NS(=O)(=O)Cc1cccc(F)c1>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)Cc3cccc(F)c3)C2)nc1C(F)F -US08269002B2,1,Fc1cccc(CBr)c1F.Oc1cc(O)nc(S)n1>>Oc1cc(O)nc(SCc2cccc(F)c2F)n1 -US20050107437A1,1,C#CCOc1ncc(F)cc1F.C[O-]>>C#CCOc1ncc(F)cc1OC -US08481542B2,3,Clc1nnc(Cl)c2c1CCC2.Fc1ccc(C[Zn+])cc1>>Fc1ccc(Cc2nnc(Cl)c3c2CCC3)cc1 -US20040192686A1,1,CC(C)(C)OC(=O)NCCN.Cc1cc2nc(Cl)n[n+]([O-])c2cc1C>>Cc1cc2nc(NCCNC(=O)OC(C)(C)C)n[n+]([O-])c2cc1C -US20070244125A1,1,O=C(c1ccc2[nH]c(C(=O)N3CCC(F)(F)CC3)cc2c1)N1CCN(C2CCC2)CC1.OB(O)c1ccc2c(c1)OCO2>>O=C(c1ccc2c(c1)cc(C(=O)N1CCC(F)(F)CC1)n2-c1ccc2c(c1)OCO2)N1CCN(C2CCC2)CC1 -US08445674B2,2,C[C@@H]1NCCN(C[C@@H](O)CC(=O)N2CCC3(CC3)[C@H](O)C2)C1=O.O=C=Nc1ccc(C(F)(F)F)c(Cl)c1>>C[C@H]1C(=O)N(C[C@@H](O)CC(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)Nc1ccc(C(F)(F)F)c(Cl)c1 -US04496560,8,O=C(CC(=O)OC(c1ccccc1)c1ccccc1)NC1=C(c2cnc(NC(=O)CCl)s2)CSC2C(Sc3ccc(Cl)c(Cl)c3)C(=O)N12.O=C(OO)c1cccc(Cl)c1>>O=C(CC(=O)OC(c1ccccc1)c1ccccc1)NC1=C(c2cnc(NC(=O)CCl)s2)CS(=O)C2C(Sc3ccc(Cl)c(Cl)c3)C(=O)N12 -US20040254185A1,2,Nc1cc2ccccc2cn1.O=C(Cl)c1cccnc1Cl>>O=C(Nc1cc2ccccc2cn1)c1cccnc1Cl -US08269011B2,7,CCCOc1ccc(F)cc1[N+](=O)[O-]>>CCCOc1ccc(F)cc1N -US20140296249A1,2,COc1ccccc1N1CCN(CCCCN)CC1.O=C(O)c1ccc2c(c1)Cc1ccccc1-2>>COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3c(c2)Cc2ccccc2-3)CC1 -US08986852B2,1,Brc1cccc2c1ccc1cc3ccccc3cc12.c1ccc(Nc2ccccc2)cc1>>c1ccc(N(c2ccccc2)c2cccc3c2ccc2cc4ccccc4cc23)cc1 -US06555552B2,6,O=S(=O)(c1ccccc1)[C@@H]1C[C@@]2(c3ccccc3)[C@H](NCc3ccccc3)CC[C@@H]1N2Cc1ccccc1>>N[C@@H]1CC[C@H]2[C@H](S(=O)(=O)c3ccccc3)C[C@]1(c1ccccc1)N2Cc1ccccc1 -US04970207,1,CN1CCNCC1.O=C(NC1N=C(c2ccccc2)c2ccccc2N(CCOCCCl)C1=O)c1cc2ccccc2[nH]1>>CN1CCN(CCOCCN2C(=O)C(NC(=O)c3cc4ccccc4[nH]3)N=C(c3ccccc3)c3ccccc32)CC1 -US20040063754A1,7,C[C@@H](c1ccccc1)N1C[C@H](C2(NC(=O)OC(C)(C)C)CC2)CC1=O>>C[C@@H](c1ccccc1)N1CC[C@@H](C2(NC(=O)OC(C)(C)C)CC2)C1 -US20090105283A1,2,Nc1cnc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1.O=C(Cl)OCc1ccccc1>>O=C(Nc1cnc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1)OCc1ccccc1 -US20100069367A1,3,CCOC(=O)c1cn(-c2ccc(Br)cc2Cl)c(-c2c(Cl)cccc2Cl)n1.CS(=O)(=O)c1cccc(B(O)O)c1>>CCOC(=O)c1cn(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2Cl)c(-c2c(Cl)cccc2Cl)n1 -US20070232610A1,3,O=[N+]([O-])c1ccc(OCc2ccccc2)c(Br)c1.OB(O)c1ccccc1>>O=[N+]([O-])c1ccc(OCc2ccccc2)c(-c2ccccc2)c1 -US04568685,2,NCCCCn1cncn1.O=C(Cl)c1ccc(Cl)c(Cl)c1>>O=C(NCCCCn1cncn1)c1ccc(Cl)c(Cl)c1 -US07618979B2,6,CCOC(=O)CC1CCCn2c1c(Sc1ccc(Cl)cc1)c1c(S(C)(=O)=O)ccnc12>>CS(=O)(=O)c1ccnc2c1c(Sc1ccc(Cl)cc1)c1n2CCCC1CC(=O)O -US09102664B2,7,O=C(O)[C@@H]1CO[C@@](CI)(c2ccc(F)cc2F)C1>>OC[C@@H]1CO[C@@](CI)(c2ccc(F)cc2F)C1 -US20080125429A1,6,COC(=O)C(CCN=[N+]=[N-])OC(C)=O>>COC(=O)C(O)CCN=[N+]=[N-] -US07067540B2,6,COc1ccn(Cc2cccc(F)c2)c(=O)c1C#N>>N#Cc1c(O)ccn(Cc2cccc(F)c2)c1=O -US20150174099A1,2,O=C(Cl)CCCCc1ccccc1.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(CCCCc1ccccc1)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20050096336A1,1,CCOC(=O)CCc1ccc(O)c2ccccc12.Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1CCl>>CCOC(=O)CCc1ccc(OCc2ccc(-c3ccc(C(F)(F)F)cc3)nc2C)c2ccccc12 -US20140171404A1,2,CC(C)(C)OC(=O)NCCC1CCNCC1.O=C(O)/C=C/c1cc(Cl)cc(Cl)c1>>CC(C)(C)OC(=O)NCCC1CCN(C(=O)/C=C/c2cc(Cl)cc(Cl)c2)CC1 -US20100331326A1,1,C[Si](C)(C)CCOCn1cnc2cc(Br)ccc21.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccc3c(c2)ncn3COCC[Si](C)(C)C)C1=O -US07544812B2,6,CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C(=O)N2C)cc1)Oc1ccccc1>>CN1C(=O)N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 -US20140309227A1,1,COC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CBr)c(F)c2n1.O=C1CCC(=O)N1>>COC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)CCC3=O)c(F)c2n1 -US05385692,3,CCCCCCCCC1Cc2ccc(B(O)O)cc2C1.CCCCCCCCCCc1cnc(-c2ccc(OS(=O)(=O)C(F)(F)F)cc2F)nc1>>CCCCCCCCCCc1cnc(-c2ccc(-c3ccc4c(c3)CC(CCCCCCCC)C4)cc2F)nc1 -US06071901,2,CCO.O=C(O)C1CNCCN1>>CCOC(=O)C1CNCCN1 -US20060160864A1,2,CCCCOCCOc1ccc(-c2ccc(N3CCC(CC(=O)OCC)C3)c(/C=C(\C)C(=O)O)c2)cc1.CCCn1cncc1C[S@](=O)c1ccc(N)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCC(CC(=O)OCC)C3)c(/C=C(\C)C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1 -US20050215605A1,2,N[C@H](c1ccccc1)c1ccccn1.O=C(O)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1>>O=C(N[C@H](c1ccccc1)c1ccccn1)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 -US07919502B2,2,NCc1csc(-c2ccccc2)n1.O=C(O)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1>>O=C(NCc1csc(-c2ccccc2)n1)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1 -US08927736B2,4,COc1cc(C=O)ccc1OCC#CI.[N-]=[N+]=NCc1cccc(C(F)(F)F)c1>>COc1cc(C=O)ccc1OCc1nnn(Cc2cccc(C(F)(F)F)c2)c1I -US07425634B2,5,CC(=O)CCOCc1ccccc1.OCCO>>CC1(CCOCc2ccccc2)OCCO1 -US20100280005A1,6,COCCCC[C@@](O)(c1ccccc1Oc1ccccc1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>COCCCCC(O)(c1ccccc1Oc1ccccc1)[C@@H]1CCCNC1 -US06277546B1,3,CC(C)(C)OC(=O)Oc1cccc(C=O)c1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1cccc(OC(=O)OC(C)(C)C)c1 -US07030286B2,7,C=CCCCC=CCOC>>CCCCCC=CCOC -US20070244125A1,1,CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1.N#Cc1ccc(B(O)O)cc1>>CC(C)N1CCN(C(=O)c2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2ccc(C#N)cc2)CC1 -US20130253197A1,3,COc1c(Br)cnn1C.COc1ccc(F)c(Cl)c1[C@@H](C)c1c[nH]c2ncc(B3OC(C)(C)C(C)(C)O3)cc12>>COc1ccc(F)c(Cl)c1[C@@H](C)c1c[nH]c2ncc(-c3cnn(C)c3OC)cc12 -US06555501B1,1,CC(C)[O-].FC(F)(F)c1ccncc1-c1nc(CCl)c(C2CC2)o1>>CC(C)OCc1nc(-c2cnccc2C(F)(F)F)oc1C1CC1 -US04801593,2,O=C(Cl)Cc1ccccc1.Oc1ccccc1>>O=C(Cc1ccccc1)Oc1ccccc1 -US05688795,1,CN(C)C(=O)c1ccccc1N.COc1ccccc1N1CCN(CCCOS(C)(=O)=O)CC1>>COc1ccccc1N1CCN(CCCNc2ccccc2C(=O)N(C)C)CC1 -US05374646,2,CCCc1nc(C)c(C(=O)O)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1.CN>>CCCc1nc(C)c(C(=O)NC)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1 -US06720423B2,1,CC(C)(CCl)c1cc(Br)ccc1O>>CC1(C)COc2ccc(Br)cc21 -US08691822B2,2,CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)O)c4c3OCC4)nc2N1C(C)C.CO[C@@H](CN)CN1CCN(CC2CC2)CC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC[C@@H](CN4CCN(CC5CC5)CC4)OC)c4c3OCC4)nc2N1C(C)C -US08288549B2,1,N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C(O)c1cc2cc(Cl)cc(Cl)c2nc1Cl>>O=C(O)c1cc2cc(Cl)cc(Cl)c2nc1N[C@@H](Cc1ccc(O)cc1)C(=O)O -US20150087585A1,2,C1CCNC1.CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)O)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)N2CCCC2)C1 -US08828987B2,2,COC(=O)c1ccc(C2(N)CC2)nc1.O=C(O)c1cc(Cl)cnc1N1CC(Oc2cccc(F)c2)C1>>COC(=O)c1ccc(C2(NC(=O)c3cc(Cl)cnc3N3CC(Oc4cccc(F)c4)C3)CC2)nc1 -US07842685B2,6,CC(=O)NC(CO)(CO)CCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1>>NC(CO)(CO)CCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 -US20100144722A1,6,COC(=O)C1(c2ccc(Nc3nc(NC(C)(C)C)cc(-c4ccccc4)n3)cc2)CCC1>>CC(C)(C)Nc1cc(-c2ccccc2)nc(Nc2ccc(C3(C(=O)O)CCC3)cc2)n1 -US05496947,6,CC(=O)NC1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccncc2F)C1>>NC1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccncc2F)C1 -US04738710,1,CCOC(=O)C(C)Br.Oc1ccc(Oc2cc3cc(Cl)ccc3nc2Cl)cc1>>CCOC(=O)C(C)Oc1ccc(Oc2cc3cc(Cl)ccc3nc2Cl)cc1 -US20140275562A1,1,COC(=O)c1ccc(-c2nc[nH]n2)cc1.FC(F)(F)C(F)(F)Oc1ccc(Br)cc1>>COC(=O)c1ccc(-c2ncn(-c3ccc(OC(F)(F)C(F)(F)F)cc3)n2)cc1 -US04348534,10,CC(C)(C)OC(=O)COc1ccc(Cl)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)C(Br)Oc1ccc(Cl)cc1 -US20090156642A1,6,CN(Cc1nc(-c2ccccc2F)c(S(=O)(=O)c2cnn(C)c2)s1)C(=O)OC(C)(C)C>>CNCc1nc(-c2ccccc2F)c(S(=O)(=O)c2cnn(C)c2)s1 -US06159904,6,Cc1c(C(=O)O)ccc2c1C1(CCS2(=O)=O)OCCO1>>Cc1c(C(=O)O)ccc2c1C(=O)CCS2(=O)=O -US20060293348A1,1,CSc1nc(Cl)c(C=O)c(Cl)n1.Nc1ccc(F)cc1F>>CSc1nc(Cl)c(C=O)c(Nc2ccc(F)cc2F)n1 -US20150018377A1,6,CCc1ccccc1Oc1ccc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)cn1>>CCc1ccccc1Oc1ccc(NC(=O)C(C)(C)N)cn1 -US07781426B2,7,CCOC(=O)C[C@@H]1CC[C@@H](CN(CC)c2ccc(C(F)(F)F)cc2C=O)CC1>>CCOC(=O)C[C@@H]1CC[C@@H](CN(CC)c2ccc(C(F)(F)F)cc2CO)CC1 -US20070043084A1,8,COc1ccc(-c2nc(CO)cn2-c2ccc(OC)cc2)cc1>>COc1ccc(-c2nc(C=O)cn2-c2ccc(OC)cc2)cc1 -US20150057260A1,3,CCOC(=O)c1nc(Br)ccc1NC(C)COC.OB(O)c1cc(Br)ccc1F>>CCOC(=O)c1nc(-c2cc(Br)ccc2F)ccc1NC(C)COC -US07183300B2,1,C=CCNC.Nc1nc(CCl)cs1>>C=CCN(C)Cc1csc(N)n1 -US20100331306A1,1,CNC(=O)c1c(-c2ccccn2)c(C(C)N)nc2ccc(F)cc12.N#Cc1c(N)ncnc1Cl>>CNC(=O)c1c(-c2ccccn2)c(C(C)Nc2ncnc(N)c2C#N)nc2ccc(F)cc12 -US20060241157A1,4,CC(=O)CC(C)=O.NNc1ccc(C(F)(F)F)cc1>>Cc1cc(C)n(-c2ccc(C(F)(F)F)cc2)n1 -US06911469B2,1,BrCc1ccccc1.COC(=O)c1ccc2nc(C)n(Cc3ccc(CO)cc3Cl)c2n1>>COC(=O)c1ccc2nc(C)n(Cc3ccc(COCc4ccccc4)cc3Cl)c2n1 -US20100137446A1,9,COc1ccc2cccc(C(F)CBr)c2c1.[N-]=[N+]=[N-]>>COc1ccc2cccc(C(F)CN=[N+]=[N-])c2c1 -US07094594B2,7,CC(C)(C)OC(=O)CC(=O)C[C@H](O)COC(=O)c1ccccc1>>CC(C)(C)OC(=O)C[C@H](O)C[C@H](O)COC(=O)c1ccccc1 -US06797710B2,7,O=C1COc2ccccc2CN1Cc1ccccc1>>c1ccc(CN2CCOc3ccccc3C2)cc1 -US07696201B2,8,CCOC(=O)N1CCC(CO)CC1>>CCOC(=O)N1CCC(C=O)CC1 -US06489324B2,6,CC(C)(C)OC(=O)N1CCN(S(C)(=O)=O)C[C@@H]1C(=O)O>>CS(=O)(=O)N1CCN[C@@H](C(=O)O)C1 -US06969730B2,1,CS(=O)(=O)OCCc1cc2cc(-c3ccc(C#N)cc3)ccc2o1.C[C@@H]1CCCN1>>C[C@@H]1CCCN1CCc1cc2cc(-c3ccc(C#N)cc3)ccc2o1 -US08173650B2,2,CC(=O)OC(C)(C)C(=O)Cl.Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1>>CC(=O)OC(C)(C)C(=O)N1CC(Cc2nc3c(N4CCOCC4)nc(-n4c(C)nc5ccccc54)nc3n2C)C1 -US04935437,9,CC(C)(C#N)c1cc(C(O)c2cccnc2)cc(C(C)(C)C#N)c1>>CC(C)(C#N)c1cc(Cc2cccnc2)cc(C(C)(C)C#N)c1 -US06277991B1,1,CCOC(=O)C(C)Br.O=C1NCN(c2ccccc2)C12CCN(Cc1cccc3ccccc13)CC2>>CCOC(=O)C(C)N1CN(c2ccccc2)C2(CCN(Cc3cccc4ccccc34)CC2)C1=O -US20100216766A1,2,Cn1cnc(-c2cc3nccc(Oc4ccc(N)cc4)c3s2)c1.O=C(Cc1ccccc1)N=C=S>>Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4)c3s2)c1 -US08987248B2,2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=C(NC1CNCC(c2ccc(OC(F)(F)F)cc2)C1)c1ccccc1>>O=C(NC1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1)c1ccccc1 -US08026257B2,2,CC(C)(C)OC(=O)N1CCC(COC(CCO)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(COC(CCOS(C)(=O)=O)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1 -US06156700,2,C#CCO.Cc1ccc(OC(C)C(=O)O)cc1-c1nsc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc12>>C#CCOC(=O)C(C)Oc1ccc(C)c(-c2nsc3ccc(-n4c(=O)cc(C(F)(F)F)n(C)c4=O)cc23)c1 -US20060019944A1,8,OC1CCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)C1>>O=C1CCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)C1 -US08119673B2,2,CCC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)O.O=C(NCc1cc(Cl)ccc1-n1cnnn1)[C@@H]1CC=NN1C(=O)[C@H](O)c1ccc(F)cc1>>CCC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)O[C@@H](C(=O)N1N=CC[C@H]1C(=O)NCc1cc(Cl)ccc1-n1cnnn1)c1ccc(F)cc1 -US05171851,7,Cc1nccn1-c1ccc([N+](=O)[O-])c(C=O)c1>>Cc1nccn1-c1ccc([N+](=O)[O-])c(CO)c1 -US08735595B2,6,COc1ccc(Oc2ncc(-c3ccc(C(C)N4C(=O)c5ccccc5C4=O)cc3)s2)cc1>>COc1ccc(Oc2ncc(-c3ccc(C(C)N)cc3)s2)cc1 -US20090209536A1,2,CCNCC.CN1CCN(c2nc(-c3ccccc3Cl)nc3ccc(C(=O)O)cc23)CC1>>CCN(CC)C(=O)c1ccc2nc(-c3ccccc3Cl)nc(N3CCN(C)CC3)c2c1 -US05470851,1,Fc1ccc2c(c1)Cc1ccccc1[C@H]1CNCCN21.O=C1c2ccccc2C(=O)N1CCBr>>O=C1c2ccccc2C(=O)N1CCN1CCN2c3ccc(F)cc3Cc3ccccc3[C@H]2C1 -US08163952B2,1,CCI.CCNc1ccc(Br)cc1C(C)(C)C>>CCN(CC)c1ccc(Br)cc1C(C)(C)C -US20100075953A1,1,C[C@H]1CN[C@H](C)CN1.Ic1ccc(OCCCN2CCCCC2)cc1>>C[C@H]1CN(c2ccc(OCCCN3CCCCC3)cc2)[C@H](C)CN1 -US20130225620A1,9,Cc1ccc(S(=O)(=O)n2ccc3c(C=O)cccc32)cc1.NO>>Cc1ccc(S(=O)(=O)n2ccc3c(C=NO)cccc32)cc1 -US20060205718A1,8,CC(=O)Nc1cccc(-c2nc(C)c(CO)[nH]2)c1>>CC(=O)Nc1cccc(-c2nc(C)c(C=O)[nH]2)c1 -US20120172599A1,3,CCCCN(CCCC)c1ccc(C=CC=Cc2cccs2)c(OC)c1.CN(C)C=O>>CCCCN(CCCC)c1ccc(C=CC=Cc2ccc(C=O)s2)c(OC)c1 -US20120165331A1,3,CCCC[Sn](CCCC)(CCCC)c1ccco1.Cc1cc(C)nc(N2CCC3(CC2)OCCN(Cc2ccccc2Br)C3=O)n1>>Cc1cc(C)nc(N2CCC3(CC2)OCCN(Cc2ccccc2-c2ccco2)C3=O)n1 -US08637670B2,2,CC(C)(C#N)c1ccc(-n2c(=O)[nH]c3cnc4ccc(Br)cc4c32)cc1.Cc1ccc(S(=O)(=O)Cl)cc1F>>Cc1ccc(S(=O)(=O)n2c(=O)n(-c3ccc(C(C)(C)C#N)cc3)c3c4cc(Br)ccc4ncc32)cc1F -US04746747,7,COc1cc(CC(=O)O)cc2c1OCO2>>COc1cc(CCO)cc2c1OCO2 -US20140113005A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ncc(Br)nc1-c1nnc(-c2ccccc2)o1>>CC(C)(C)OC(=O)Nc1ncc(Br)nc1-c1nnc(-c2ccccc2)o1 -US20150191481A1,4,CN(C)c1c(F)cc(-c2cc(=O)c3ccc(N)c(N)c3o2)cc1F.O=C(n1ccnc1)n1ccnc1>>CN(C)c1c(F)cc(-c2cc(=O)c3ccc4[nH]c(=O)[nH]c4c3o2)cc1F -US20080269192A1,1,C[C@H](N)CO.Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C>>Cc1nc(Cl)c([N+](=O)[O-])c(N[C@@H](C)CO)c1C -US20140336190A1,3,CCS(=O)(=O)Nc1nc2c(I)cc(-c3c(C)noc3C)cc2[nH]1.Cc1ccc2ncccc2c1B(O)O>>CCS(=O)(=O)Nc1nc2c(-c3c(C)ccc4ncccc34)cc(-c3c(C)noc3C)cc2[nH]1 -US20150148313A1,1,CN(Cc1cc([N+](=O)[O-])cc(F)c1O)C(=O)OC(C)(C)C.O[C@H]1CCOC1>>CN(Cc1cc([N+](=O)[O-])cc(F)c1O[C@@H]1CCOC1)C(=O)OC(C)(C)C -US20140243322A1,2,CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OCCOCCOCCOCCOCCOCCOCCN)ccc2-n2c(C)nnc21.COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)O)c1nnc(C)n1-2>>CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OCCOCCOCCOCCOCCOCCOCCNC(=O)C[C@@H]3N=C(c4ccc(Cl)cc4)c4cc(OC)ccc4-n4c(C)nnc43)ccc2-n2c(C)nnc21 -US20150094296A1,7,CCOc1cc([N+](=O)[O-])ccc1C(=O)OC(C)(C)C>>CCOc1cc(N)ccc1C(=O)OC(C)(C)C -US20150080438A1,9,BrC(Br)(Br)Br.OCCCCCCC1=C(c2ccc(F)c(O)c2)CCCc2cc(O)c(F)cc21>>Oc1cc(C2=C(CCCCCCBr)c3cc(F)c(O)cc3CCC2)ccc1F -US20080132477A1,6,C=CCOc1cccc(C(=O)OCC)c1>>C=CCOc1cccc(C(=O)O)c1 -US20070043028A1,1,C=CCN1C[C@H](C)N([C@@H](c2cccc(O)c2)c2cccc(C(=O)N3CCC(=O)CC3)c2)C[C@H]1C.CCOC(=O)CCCN>>C=CCN1C[C@H](C)N([C@@H](c2cccc(O)c2)c2cccc(C(=O)N3CCC(NCCCC(=O)OCC)CC3)c2)C[C@H]1C -US07244740B2,3,C#C[Mg+].COc1cccc(-c2nc3c(Cl)cccn3c2C=O)c1>>C#CC(O)c1c(-c2cccc(OC)c2)nc2c(Cl)cccn12 -US06927292B2,7,CC(=O)N1c2c(ccn3c(C)c(C)nc23)C(=O)[C@H](OC(=O)C(C)(C)C)[C@H]1c1ccccc1>>CC(=O)N1c2c(ccn3c(C)c(C)nc23)[C@@H](O)[C@H](OC(=O)C(C)(C)C)[C@H]1c1ccccc1 -US20150272947A1,2,CC(=O)OC(C)=O.COC(=O)[C@@H]1CC[C@H](N)C1>>COC(=O)[C@@H]1CC[C@H](NC(C)=O)C1 -US20150225396A1,2,COc1cccc(-c2nnc(C3CCNCC3)o2)c1.O=C(O)CCCc1nc2ccccc2c(=O)[nH]1>>COc1cccc(-c2nnc(C3CCN(C(=O)CCCc4nc5ccccc5c(=O)[nH]4)CC3)o2)c1 -US04130561,7,CC1(Oc2ccc([N+](=O)[O-])cc2)C2CC3CC(C2)CC1C3>>CC1(Oc2ccc(N)cc2)C2CC3CC(C2)CC1C3 -US20130274244A1,7,C=C(C)c1cccc(C(=O)OCC)n1>>CCOC(=O)c1cccc(C(C)C)n1 -US06310070B1,2,Cc1ccc(Cn2cnc(N)c2C(N)=O)cc1.O=C(O)c1cccnc1>>Cc1ccc(Cn2cnc(NC(=O)c3cccnc3)c2C(N)=O)cc1 -US20040138223A1,1,CC(C)c1ccc(N(Cc2cn[nH]c2)C(=O)C2CCOc3c2cccc3[N+](=O)[O-])cc1.CCI>>CCn1cc(CN(C(=O)C2CCOc3c2cccc3[N+](=O)[O-])c2ccc(C(C)C)cc2)cn1 -US20060258644A1,2,Cc1ccccc1-c1ccc(C(=O)O)cc1C.c1ccc2c(c1)Cn1cccc1CN2>>Cc1ccccc1-c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1C -US09096592B2,1,CC(C)I.Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)nc2[nH]c(=O)[nH]c12>>CC(C)n1c(=O)[nH]c2c(N)nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc21 -US06100258,9,CCN(Cc1cc(Br)ccc1O)c1ccc(C(N)=O)nn1>>CCN(Cc1cc(Br)ccc1O)c1ccc(C#N)nn1 -US04199519,2,C1COCCN1.CC(C)=CCC/C(C)=C/CC/C(=C\CC/C(C)=C/C(=O)O)CO>>CC(C)=CCC/C(C)=C/CC/C(=C\CC/C(C)=C/C(=O)N1CCOCC1)CO -US20120270865A2,6,CCOC(=O)CCN(C)C(=O)c1ccc(NC(CCCCS(C)(=O)=O)c2oc3ccc(OC)cc3c2C)cc1>>COc1ccc2oc(C(CCCCS(C)(=O)=O)Nc3ccc(C(=O)N(C)CCC(=O)O)cc3)c(C)c2c1 -US20150183775A1,1,CC(C)(C)OC(N)=O.COC(=O)c1ccc(F)cc1Oc1cnc(Cl)c(F)c1>>COC(=O)c1ccc(F)cc1Oc1cnc(NC(=O)OC(C)(C)C)c(F)c1 -US08563550B2,1,Brc1nn2ccnc2s1.Nc1ccc(F)cc1>>Fc1ccc(Nc2nn3ccnc3s2)cc1 -US20090227579A1,7,CN(c1nc(C#N)nc(N(CCOCc2ccccc2)CCO[Si](C)(C)C(C)(C)C)c1[N+](=O)[O-])C1CCCC1>>CN(c1nc(C#N)nc(N(CCOCc2ccccc2)CCO[Si](C)(C)C(C)(C)C)c1N)C1CCCC1 -US20130345181A1,1,CC(C)(C)OC(=O)n1cc(-c2cc3cnc(Br)cc3n2C(=O)OC(C)(C)C)cn1.Nc1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)n1cc(-c2cc3cnc(Nc4ccc(C(F)(F)F)cc4)cc3n2C(=O)OC(C)(C)C)cn1 -US20060084690A1,2,CO.O=C(O)CCc1conc1-c1ccc(Cl)c(Cl)c1>>COC(=O)CCc1conc1-c1ccc(Cl)c(Cl)c1 -US08003649B2,1,CC(C)(c1ccc(F)cc1)N1CCNCC1.FC(F)c1nnc2ccc(Cl)nn12>>CC(C)(c1ccc(F)cc1)N1CCN(c2ccc3nnc(C(F)F)n3n2)CC1 -US20110166121A1,1,O=C1CNC(=O)N1.OCCCl>>O=C1CNC(=O)N1CCO -US06831193B2,1,N[C@H]1CCCc2ccccc21.O=Cc1cccc(Oc2ccccc2)c1>>c1ccc(Oc2cccc(CN[C@H]3CCCc4ccccc43)c2)cc1 -US05912247,2,C=CCCOc1nc(N2CCNCC2)nc2ccccc12.O=C(Cl)OCc1ccccc1>>C=CCCOc1nc(N2CCN(C(=O)OCc3ccccc3)CC2)nc2ccccc12 -US08263588B2,1,O=C(CCl)Nc1ccccc1CO>>O=C1COCc2ccccc2N1 -US20130252953A1,2,CCOC(=O)N1CCNCC1.O=C(Cl)CCCCl>>CCOC(=O)N1CCN(C(=O)CCCCl)CC1 -US20110124635A1,3,C=C(C)CBr.O=C(CCCl)c1ccccc1>>C=C(C)CC(O)(CCCl)c1ccccc1 -US08420635B2,6,COC(=O)c1cc([N+](=O)[O-])ccc1-c1cccnc1O>>O=C(O)c1cc([N+](=O)[O-])ccc1-c1cccnc1O -US08084628B2,7,CC(=O)Oc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1C>>CC(=O)Oc1ccc2c(c1C)OCC(c1ccc(O)cc1)C2=O -US05234942,2,COC(=O)c1ccc(Cn2ccc3ccc(N)cc32)o1.O=C(Cl)OC1CCCC1>>COC(=O)c1ccc(Cn2ccc3ccc(NC(=O)OC4CCCC4)cc32)o1 -US07425634B2,2,CS(=O)(=O)Cl.Cc1cnc(CO)c(C)c1OCC1COC(C)(C)OC1>>Cc1cnc(COS(C)(=O)=O)c(C)c1OCC1COC(C)(C)OC1 -US04870074,9,ClCC1CN(Cc2ccccc2)CCO1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC1CN(Cc2ccccc2)CCO1 -US20050203087A1,2,CO.O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4Cl)CC3)c2)c1Br>>COC(=O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4Cl)CC3)c2)c1Br -US09145438B2,6,COc1ccc(CNc2ncnc3c2ccn3[C@@H]2O[C@H](CN(CCCN3C(=O)c4ccccc4C3=O)C(C)C)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1>>COc1ccc(CNc2ncnc3c2ccn3[C@@H]2O[C@H](CN(CCCN)C(C)C)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1 -US20150018328A1,9,Fc1ccc(F)c(-c2nc(NC3CCC(F)(F)CC3)nc(NC3CCC(F)(F)CC3)n2)n1.NN>>NNc1ccc(F)c(-c2nc(NC3CCC(F)(F)CC3)nc(NC3CCC(F)(F)CC3)n2)n1 -US05618816,1,COc1cnccc1N1CCNCC1.O=[N+]([O-])c1ccc2[nH]cc(CCCI)c2c1>>COc1cnccc1N1CCN(CCCc2c[nH]c3ccc([N+](=O)[O-])cc23)CC1 -US05972946,1,BrCC1CC1.Cc1nc(-c2ccccc2)nc(OCC(=O)Nc2ccccc2)c1C>>Cc1nc(-c2ccccc2)nc(OCC(=O)N(CC2CC2)c2ccccc2)c1C -US20070093521A1,2,O=C(Cl)c1ccccc1.O=[N+]([O-])c1c(O)cccc1O>>O=C(Oc1cccc(O)c1[N+](=O)[O-])c1ccccc1 -US20140296261A1,2,CCCS(=O)(=O)Cl.Nc1ccc(F)c([N+](=O)[O-])c1>>CCCS(=O)(=O)Nc1ccc(F)c([N+](=O)[O-])c1 -US05139563,1,CCOC(=O)CBr.Cc1cc(C)nc(O)n1>>CCOC(=O)COc1nc(C)cc(C)n1 -US20090298899A1,3,CCOC(=O)C=Cc1cccc(NC(=O)c2csc(Cl)n2)c1.OB(O)c1ccccc1>>CCOC(=O)C=Cc1cccc(NC(=O)c2csc(-c3ccccc3)n2)c1 -US20070123527A1,7,CNC(=O)C=C(c1ccc2cc[nH]c2c1)c1ccccn1>>CNC(=O)CC(c1ccc2cc[nH]c2c1)c1ccccn1 -US07709503B2,2,Cc1[nH]c(C(=O)NC2CCN(c3nc(CNC(=O)c4ccccc4C(=O)O)c(C(=O)O)s3)CC2)c(Cl)c1Cl>>Cc1[nH]c(C(=O)NC2CCN(c3nc(CN4C(=O)c5ccccc5C4=O)c(C(=O)O)s3)CC2)c(Cl)c1Cl -US20080207728A1,6,COC(=O)c1cc(I)cc2c1OCC=C2>>O=C(O)c1cc(I)cc2c1OCC=C2 -US08163737B2,1,CC(C)(C)CCN.O=Cc1cccc(F)c1NCCN1CCOCC1>>CC(C)(C)CC/N=C/c1cccc(F)c1NCCN1CCOCC1 -US09132126B2,2,FC(F)(F)c1cccc(N2CCNCC2)c1.Nc1onc(-c2ccccc2Cl)c1C(=O)O>>Nc1onc(-c2ccccc2Cl)c1C(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1 -US08344135B2,2,CC(C)(C)OC(=O)Nc1cccc(Oc2ccc3nc(N)sc3n2)c1.O=C(Cl)C1CC1>>CC(C)(C)OC(=O)Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)c1 -US07615642B2,2,CN.O=C(O)c1cc[nH]c1>>CNC(=O)c1cc[nH]c1 -US04725600,1,CI.COc1ccc(-c2cc(=O)[nH]c(C)n2)cc1OC>>COc1ccc(-c2cc(=O)n(C)c(C)n2)cc1OC -US05750735,2,CS(=O)(=O)Cl.C[C@H]1C[C@H](O)[C@@H](CN=[N+]=[N-])O1>>C[C@H]1C[C@H](OS(C)(=O)=O)[C@@H](CN=[N+]=[N-])O1 -US20080214615A1,2,CNCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C=Nc1ccc(Cl)cc1>>CN(Cc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)C(=O)Nc1ccc(Cl)cc1 -US06878705B2,7,Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(C#CCCCO)oc21>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCCCCO)oc21 -US05710314,1,Cc1ccc(C)c(O)c1.N#CC(=NOC(F)F)c1ccccc1CBr>>Cc1ccc(C)c(OCc2ccccc2C(C#N)=NOC(F)F)c1 -US20120010189A1,2,CCOC(=O)c1nnc(-c2ccccc2)o1.CN(C)Cc1ccc(OC2CNC2)cc1>>CN(C)Cc1ccc(OC2CN(C(=O)c3nnc(-c4ccccc4)o3)C2)cc1 -US20150252030A1,3,Cc1cc(C)c(O)c(Br)c1.OB(O)c1ccoc1>>Cc1cc(C)c(O)c(-c2ccoc2)c1 -US20120071479A1,1,CCCN(CCC)C(=O)CCl.Nc1nc(N)c(C(=O)/N=C2\NCC3(CCN(C(=O)CCc4ccc(OCC(=O)O)cc4)CC3)N2)nc1Cl>>CCCN(CCC)C(=O)COC(=O)COc1ccc(CCC(=O)N2CCC3(CC2)CN/C(=N\C(=O)c2nc(Cl)c(N)nc2N)N3)cc1 -US20100120763A1,3,COc1cc(C(F)(F)F)cc2c1nnc1c(C)nc(Br)n12.Cc1cnccc1B(O)O>>COc1cc(C(F)(F)F)cc2c1nnc1c(C)nc(-c3ccncc3C)n12 -US20100152160A1,6,CCOC(=O)C1COc2cc(Cl)c(Cl)cc2O1>>O=C(O)C1COc2cc(Cl)c(Cl)cc2O1 -US20100168167A1,6,CC(=O)Nc1c(O)cccc1F>>Nc1c(O)cccc1F -US20150057279A1,2,Cc1cncc(NCCN)n1.O=C(O)/C=C/C(F)(F)F>>Cc1cncc(NCCNC(=O)/C=C/C(F)(F)F)n1 -US20120101123A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCOC(=O)CCn1ccc2c(Br)ccnc21>>CCOC(=O)CCn1ccc2c(B3OC(C)(C)C(C)(C)O3)ccnc21 -US20060089347A1,1,O=Cc1ccccc1.c1cc2c(cc1OCCCN1CCCCC1)CCNCC2>>c1ccc(CN2CCc3ccc(OCCCN4CCCCC4)cc3CC2)cc1 -US08258134B2,2,CC(C)(O)Cn1ccc(N)n1.O=C(O)C(CC1CCC1)n1ncc(Oc2c(F)cccc2F)cc1=O>>CC(C)(O)Cn1ccc(NC(=O)C(CC2CCC2)n2ncc(Oc3c(F)cccc3F)cc2=O)n1 -US05886181,7,CCC(=O)N1CCN(C=O)C=C1C(=O)NC(C)(C)C>>CCC(=O)N1CCN(C=O)C[C@H]1C(=O)NC(C)(C)C -US08785639B2,4,CCc1c[nH]c2ncc(C=O)c(Cl)c12.CNN>>CCc1c[nH]c2ncc3cnn(C)c3c12 -US20100130446A1,2,C1CNC1.O=C(O)c1ccc(C(CC2CCOCC2)c2ccc(-c3ncc(CO)s3)[nH]2)cc1>>O=C(c1ccc(C(CC2CCOCC2)c2ccc(-c3ncc(CO)s3)[nH]2)cc1)N1CCC1 -US05506252,7,COc1cc(C#N)ccc1[N+](=O)[O-]>>COc1cc(C#N)ccc1N -US08481542B2,3,Cc1c(Cl)nnc(N2CCN[C@H](C)C2)c1C.OB(O)c1ccc(F)cc1>>Cc1c(-c2ccc(F)cc2)nnc(N2CCN[C@H](C)C2)c1C -US03950307,2,O=C(Cl)c1c(Br)c(Br)c(Br)c(Br)c1Br.O=C1NC(=O)c2c(Br)c(Br)c(Br)c(Br)c21>>O=C(c1c(Br)c(Br)c(Br)c(Br)c1Br)N1C(=O)c2c(Br)c(Br)c(Br)c(Br)c2C1=O -US20090325952A1,6,CN(CCO)CCCCCCCC(=O)Nc1ccc(C(=O)OC(C)(C)C)cc1>>CN(CCO)CCCCCCCC(=O)Nc1ccc(C(=O)O)cc1 -US04500526,2,Nc1nc2cnccc2s1.O=C(Cl)Oc1ccccc1>>O=C(Nc1nc2cnccc2s1)Oc1ccccc1 -US20060160803A1,6,COC(=O)CCc1cccc(Oc2ccnc(C(=O)OC(C)(C)C)c2)c1>>COC(=O)CCc1cccc(Oc2ccnc(C(=O)O)c2)c1 -US06313116B1,2,CCc1nc2c(OC)ccc(C(=O)O)c2s1.Cn1nccc1N>>CCc1nc2c(OC)ccc(C(=O)Nc3ccnn3C)c2s1 -US20040006233A1,7,COc1ccc(CCC(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1OC>>COc1ccc(CCC(O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1OC -US20090099184A1,2,CS(=O)(=O)c1ccc(CN)c(Cl)c1.O=C(O)c1ccc(F)nc1>>CS(=O)(=O)c1ccc(CNC(=O)c2ccc(F)nc2)c(Cl)c1 -US08183262B2,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.Cc1cc(-c2ccc(Cl)cc2)nc(-n2cnc(Br)c2)n1>>Cc1cc(-c2ccc(Cl)cc2)nc(-n2cnc(-c3cnc(N)nc3)c2)n1 -US20120115869A1,1,CCC(=O)Nc1cccc(C#N)c1.Cc1onc(-c2ccccc2)c1CBr>>CCC(=O)N(Cc1c(-c2ccccc2)noc1C)c1cccc(C#N)c1 -US20040110778A1,1,CCNCC.CCOC(=O)c1c[nH]c2c1-c1nn(CCOS(C)(=O)=O)cc1CCC2>>CCOC(=O)c1c[nH]c2c1-c1nn(CCN(CC)CC)cc1CCC2 -US20030236297A1,7,CCOC(=O)C(C)(CCc1cccs1)NC(=O)OC>>COC(=O)NC(C)(CO)CCc1cccs1 -US20100160335A1,3,CCC(=O)Nc1c(OC)cccc1OC(=O)CC>>CCC(=O)Nc1c(OC)ccc(C(=O)CC)c1O -US04794181,1,BrCCCOc1ccccc1.COc1cc2c(cc1OC)C(Oc1ccccc1)CNCC2>>COc1cc2c(cc1OC)C(Oc1ccccc1)CN(CCCOc1ccccc1)CC2 -US08093239B2,1,COc1cc(CCN2CCN(C)CC2)ccc1N.O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)c1>>COc1cc(CCN2CCN(C)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US20070197584A1,1,O=[N+]([O-])c1ccc(F)cc1.OC[C@@H]1CCCN2CCCC[C@H]12>>O=[N+]([O-])c1ccc(OC[C@@H]2CCCN3CCCC[C@H]23)cc1 -US03963765,7,CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@H]4[C@@H]3CC[C@@]2(O)C1>>C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@]4(O)C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C -US04094982,2,CCN.O=[N+]([O-])c1cncc(S(=O)(=O)O)c1>>CCNS(=O)(=O)c1cncc([N+](=O)[O-])c1 -US20090311217A1,3,CNC(=O)Nc1ccc2c(c1)C(=O)CO2.COCCOc1ccc2[nH]c(-c3c(C)nn(C)c3C)c(C=O)c2c1>>CNC(=O)Nc1ccc2c(c1)C(=O)/C(=C/c1c(-c3c(C)nn(C)c3C)[nH]c3ccc(OCCOC)cc13)O2 -US20090298866A1,7,CCOC(=O)c1csc(-n2cc(CC(C)C)c3ccc(Cl)cc32)n1>>CC(C)Cc1cn(-c2nc(CO)cs2)c2cc(Cl)ccc12 -US04241069,3,C=O.CNC.O=C1CC(c2ccccc2)Oc2ccccc21>>CN(C)CC1C(=O)c2ccccc2OC1c1ccccc1 -US20060063779A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cc2)C(=O)C1>>O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(N2CCNCC2=O)cc1 -US03971797,1,CCOC(=O)CBr.Cc1ncc(CS)c2c1OC(C)(C)OC2>>CCOC(=O)CSCc1cnc(C)c2c1COC(C)(C)O2 -US20100022603A1,2,CC(=O)OC(C)=O.NC1Cc2ccccc2C1>>CC(=O)NC1Cc2ccccc2C1 -US04333928,8,C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3CC[C@]2(C)[C@H]1O>>C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3CC[C@]2(C)C1=O -US20020035102A1,8,OC1CN(C(c2cccs2)c2cccs2)C1>>O=C1CN(C(c2cccs2)c2cccs2)C1 -US20150057271A1,2,CC(=O)OC(C)=O.COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(c2)NCCN3c2ccc(C(F)(F)F)cc2Cl)c(OC)c1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(c2)N(C(C)=O)CCN3c2ccc(C(F)(F)F)cc2Cl)c(OC)c1 -US20060229346A1,4,CC(=O)NC(N)=S.O=C(CBr)c1cccc(CCO)c1>>CC(=O)Nc1nc(-c2cccc(CCO)c2)cs1 -US20080193700A1,2,CC(C)(C)N=C=O.Cc1nc2ccc(N)cc2s1>>Cc1nc2ccc(NC(=O)NC(C)(C)C)cc2s1 -US04122255,1,CN(C)CCCOc1ccccc1C=O.NCc1ccccc1>>CN(C)CCCOc1ccccc1C=NCc1ccccc1 -US04588720,7,CCOC(=O)c1cn2c(C)c(CC)c(OC)nc2n1>>CCc1c(OC)nc2nc(CO)cn2c1C -US04808620,1,CC(=O)Cl.CC(C)(C)c1cc(-c2n[nH]c3ncccc23)cc(C(C)(C)C)c1O>>CC(=O)n1nc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2cccnc21 -US20100087434A1,7,O=[N+]([O-])c1cc(Br)cc(CO)c1>>Nc1cc(Br)cc(CO)c1 -US05364871,3,C[Mg+].NC(=O)c1cccc(C=O)n1>>CC(O)c1cccc(C(N)=O)n1 -US07700604B2,3,C#C[Si](C)(C)C.COc1cc(I)c(C=O)cn1>>COc1cc(C#C[Si](C)(C)C)c(C=O)cn1 -US20120157430A1,2,COc1c(C(C)N)cc(Cl)c(C)c1Br.O=C(Cl)OCc1ccccc1>>COc1c(C(C)NC(=O)OCc2ccccc2)cc(Cl)c(C)c1Br -US20140005175A1,2,CC(C)(C(=O)O)c1ccc(S(=O)(=O)/C=C/C#N)cc1.NCC1CC1>>CC(C)(C(=O)NCC1CC1)c1ccc(S(=O)(=O)/C=C/C#N)cc1 -US20140243353A1,3,CC1(C)OB(/C=C/c2ccccc2)OC1(C)C.COc1cc(Br)cnc1OC>>COc1cc(/C=C/c2ccccc2)cnc1OC -US20100168101A1,1,NNC(=O)c1ccc(NC(=O)c2ccco2)cc1.O=C1Nc2ccc(I)cc2C1=O>>O=C1Nc2ccc(I)cc2C1=NNC(=O)c1ccc(NC(=O)c2ccco2)cc1 -US20080176830A1,2,CCOC(=O)CNCc1cc(-c2ccc(C(F)(F)F)cc2)ccc1N>>O=C1CNCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1 -US20100069457A1,9,O=C(O)Cc1ccc(N2C(=O)c3c(c(OCC(F)F)c4ccccc4c3OCC(F)F)C2O)c(Cl)c1>>O=C(O)Cc1ccc(N2Cc3c(c(OCC(F)F)c4ccccc4c3OCC(F)F)C2=O)c(Cl)c1 -US06124280,9,CC(CCC(O)(c1ccccc1)c1ccccc1)(c1ccc(O)cc1)c1ccc(O)cc1>>CC(CCC(c1ccccc1)c1ccccc1)(c1ccc(O)cc1)c1ccc(O)cc1 -US20080070935A1,1,Cc1c[nH]c2c1C(=O)CC(C)(C)C2.Nc1nc(N)c2ccc(F)cc2n1>>Cc1cn(-c2ccc3c(N)nc(N)nc3c2)c2c1C(=O)CC(C)(C)C2 -US20040138286A1,6,Cc1c(NC2CC3CCC(C2)N3Cc2ccccc2)ccc2[nH]ncc12>>Cc1c(NC2CC3CCC(C2)N3)ccc2[nH]ncc12 -US20060189591A1,9,Cc1ccc(C(N)=O)cn1>>Cc1ccc(C#N)cn1 -US06380228B1,6,CC(C)(C)OC(=O)NCCS(=O)(=O)c1ccccc1>>NCCS(=O)(=O)c1ccccc1 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.OB(O)c1cccnc1>>CCCNC(=O)c1nnc2c(-c3cccnc3)cccc2c1N -US04508921,6,C[C@@](Cc1ccc(O)cc1)(NC(=O)OCc1ccccc1)C(=O)O>>C[C@](N)(Cc1ccc(O)cc1)C(=O)O -US20120214735A1,6,CCOC(=O)C(OC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1>>O=C(O)C(OC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1 -US20070037781A1,3,C=CC(=O)OC.CC(=O)c1cc(OCc2ccccc2)cc([N+](=O)[O-])c1OS(=O)(=O)C(F)(F)F>>COC(=O)C=Cc1c(C(C)=O)cc(OCc2ccccc2)cc1[N+](=O)[O-] -US06177444B1,6,Nc1sc2c(c1C(=O)c1ccc(Cl)cc1)CCN(C(=O)OCc1ccccc1)C2>>Nc1sc2c(c1C(=O)c1ccc(Cl)cc1)CCNC2 -US08501746B2,2,NCc1ccccc1.O=C(O)c1csc(Br)c1>>O=C(NCc1ccccc1)c1csc(Br)c1 -US06399629B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@H]1C[C@@H](O)CCN1>>COC(=O)[C@H]1C[C@@H](O)CCN1C(=O)OC(C)(C)C -US06962935B2,6,CCOC(=O)c1sc(Cl)nc1-c1cccc(C#N)c1>>N#Cc1cccc(-c2nc(Cl)sc2C(=O)O)c1 -US05670504,1,CSc1ccc(NN=C(Cl)C(C)=O)cc1.Sc1ccc(Cl)cc1>>CSc1ccc(NN=C(Sc2ccc(Cl)cc2)C(C)=O)cc1 -US04870076,2,NCCc1ccco1.O=S(=O)(O)c1ccccc1>>O=S(=O)(NCCc1ccco1)c1ccccc1 -US06818644B1,1,O=C(NCC(F)(F)F)C1(CCCCBr)c2ccccc2-c2ccccc21.c1ccc(N2CCNCC2)nc1>>O=C(NCC(F)(F)F)C1(CCCCN2CCN(c3ccccn3)CC2)c2ccccc2-c2ccccc21 -US20140336377A1,2,CC(N)c1cnc(OCC(F)(F)F)c(Cl)c1.Cc1cc(C(=O)O)nc(N)n1>>Cc1cc(C(=O)NC(C)c2cnc(OCC(F)(F)F)c(Cl)c2)nc(N)n1 -US20150005275A1,2,NC(=O)c1cc(S(=O)(=O)N2CCC(F)(F)CC2)sc1N.O=C(O)c1ccccc1F>>NC(=O)c1cc(S(=O)(=O)N2CCC(F)(F)CC2)sc1NC(=O)c1ccccc1F -US20090163471A1,6,CCNc1c(C)c(C(=O)OC(C)(C)C)cc(C)c1C(=O)OC>>CCNc1c(C)c(C(=O)OC(C)(C)C)cc(C)c1C(=O)O -US20090192162A1,3,C#Cc1ccc(S(C)(=O)=O)cc1.CCOC(=O)COc1ccc(Sc2cc(Br)cc(Oc3ncccc3C(F)(F)F)c2)cc1C>>CCOC(=O)COc1ccc(Sc2cc(C#Cc3ccc(S(C)(=O)=O)cc3)cc(Oc3ncccc3C(F)(F)F)c2)cc1C -US20070185103A1,6,COC(=O)C1CC(c2ccccc2)CN(C(=O)N[C@H](C)c2ccccc2)C1>>C[C@@H](NC(=O)N1CC(C(=O)O)CC(c2ccccc2)C1)c1ccccc1 -US20040097733A1,1,CC=O.CCCCCCOc1cc2c(cc1Nc1ccc(C(=O)OCC)cc1)C(C)=CCC2(C)C>>CCCCCCOc1cc2c(cc1N(CC)c1ccc(C(=O)OCC)cc1)C(C)=CCC2(C)C -US05608075,4,CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2C#N)cc1.[N-]=[N+]=[N-]>>CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US20100298324A1,2,COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc1OC.Nc1ccc(C(=O)c2ccccc2)cc1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)Nc4ccc(C(=O)c5ccccc5)cc4)ccc3c2=O)nc1OC -US07879852B2,3,CC1(C)CCC(N(C(=O)C(C)(C)C=O)[C@H]2CCN(C(=O)OC(C)(C)C)C2)CC1.C[Mg+]>>CC(O)C(C)(C)C(=O)N(C1CCC(C)(C)CC1)C1CCN(C(=O)OC(C)(C)C)C1 -US08063234B2,9,CCSCc1cccc2c(C(CCOS(C)(=O)=O)c3ccc(Cl)cc3)c[nH]c12.[C-]#N>>CCSCc1cccc2c(C(CCC#N)c3ccc(Cl)cc3)c[nH]c12 -US07265246B2,1,BrCc1csc(-c2ccccc2)c1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1csc(-c2ccccc2)c1 -US20080051398A1,1,COc1ccc(N(C)c2nc(Cl)nc3ccccc23)cc1.C[S-]>>COc1ccc(N(C)c2nc(SC)nc3ccccc23)cc1 -US06949542B2,2,CCc1cc(C)c(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)cn1.Cc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>CCc1cc(C)c(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(C)cc3NC(=O)OC(C)(C)C)c2)cn1 -US20150266874A1,2,Nc1c[nH]nc1-c1nc2ccccc2s1.O=C(Cl)C1CCCC1>>O=C(Nc1c[nH]nc1-c1nc2ccccc2s1)C1CCCC1 -US08450304B2,1,O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CNC1.O=C1CCC(O)(c2ccc(Br)cn2)CC1>>O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(O)(c3ccc(Br)cn3)CC2)C1 -US20110251166A1,8,OCC(F)(F)c1ccccc1>>O=CC(F)(F)c1ccccc1 -US20070060629A1,1,CN(C)CCCl.Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(=O)(=O)NC(=O)OC(C)(C)C)cc2)cc1>>Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(=O)(=O)N(CCN(C)C)C(=O)OC(C)(C)C)cc2)cc1 -US20120095048A1,1,CCOC(=O)Cl.c1ccc2[nH]nnc2c1>>CCOC(=O)n1nnc2ccccc21 -US20070265265A1,4,COC(=O)c1ccc(C(=O)CBr)o1.NC(N)=S>>COC(=O)c1ccc(-c2csc(N)n2)o1 -US20110118322A1,3,COC(=O)c1cccc(COc2ccc(I)cc2)c1.OB(O)c1cc(F)c(F)cc1F>>COC(=O)c1cccc(COc2ccc(-c3cc(F)c(F)cc3F)cc2)c1 -US05278148,1,CN.O=S(=O)(CCCO)c1ccccc1>>CNCCCS(=O)(=O)c1ccccc1 -US06835731B2,2,NCc1ccc(CO)cc1.O=C(O)c1ccccn1>>O=C(NCc1ccc(CO)cc1)c1ccccn1 -US20040138223A1,2,COc1ccc(N)cn1.O=C(O)C1CCCc2c(OCc3ccccc3)cccc21>>COc1ccc(NC(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1 -US20150164904A1,7,Cc1ccc(-n2ccc(NC(=O)c3cc(N4CCCCC4)ccc3[N+](=O)[O-])n2)cc1C>>Cc1ccc(-n2ccc(NC(=O)c3cc(N4CCCCC4)ccc3N)n2)cc1C -US08431695B2,1,NCc1ccc(-c2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)cc1.O=C1CCCC1>>Nc1ncnn2c(-c3ccc(CNC4CCCC4)cc3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12 -US07772244B2,3,CC(C)(C)C(=O)Nc1c(F)cccc1Br.CN(C)C=O>>CC(C)(C)C(=O)Nc1c(F)cccc1C=O -US20100130474A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cncc(-c2cc(N)[nH]n2)c1>>COc1cncc(-c2cc(N)n(C(=O)OC(C)(C)C)n2)c1 -US20140128424A1,2,Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)O.NC1(CO)CCC1>>Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC1(CO)CCC1 -US20100267666A1,3,CCOC(=O)c1c(C)[nH]c2ncc(Br)nc12.COc1cc(B(O)O)cc(OC)c1OC>>CCOC(=O)c1c(C)[nH]c2ncc(-c3cc(OC)c(OC)c(OC)c3)nc12 -US20150175599A1,7,COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cn3)c3ccc([N+](=O)[O-])cc23)ccn1>>COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cn3)c3ccc(N)cc23)ccn1 -US20050272784A1,6,CCOC(=O)C(Cc1ccc(Cl)cc1)NC(=O)c1cc(-c2ccc(-c3ccccc3)cc2)nn1-c1cccc(C(F)(F)F)c1>>O=C(NC(Cc1ccc(Cl)cc1)C(=O)O)c1cc(-c2ccc(-c3ccccc3)cc2)nn1-c1cccc(C(F)(F)F)c1 -US20100331293A1,3,Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl.Cn1ccc2cc(B3OC(C)(C)C(C)(C)O3)ccc21>>Cc1c(-c2ccc3c(ccn3C)c2)nc2cc(F)cc(F)c2c1Cl -US04125531,7,C=CCC(CC1CC2CCN1CC2)(c1ccccc1)c1ccccc1>>CCCC(CC1CC2CCN1CC2)(c1ccccc1)c1ccccc1 -US20100273816A1,1,CS(=O)(=O)c1cc(Cl)cc(Cl)c1.Oc1ccc(Cl)c(-c2ncnc3c(C(F)(F)F)cccc23)c1>>CS(=O)(=O)c1cc(Cl)cc(Oc2ccc(Cl)c(-c3ncnc4c(C(F)(F)F)cccc34)c2)c1 -US07947727B2,2,CCNCC(O)(CNc1cccc2c1cnn2-c1ccccc1)C(F)(F)F.Cc1ccccc1C(=O)O>>CCN(CC(O)(CNc1cccc2c1cnn2-c1ccccc1)C(F)(F)F)C(=O)c1ccccc1C -US20090029947A1,3,C#CCOCc1ccccc1.COC(=O)[C@@]1(N)CC[C@@H](c2ccc(Br)cc2)C1>>COC(=O)[C@@]1(N)CC[C@@H](c2ccc(C#CCOCc3ccccc3)cc2)C1 -US20090069288A1,5,O=Cc1ccc(Br)cc1.OCCO>>Brc1ccc(C2OCCO2)cc1 -US08637525B2,1,CCNC.Clc1nc(Cl)c2c(n1)C(c1ccccc1)CC2>>CCN(C)c1nc(Cl)nc2c1CCC2c1ccccc1 -US20140073620A1,2,CC(=O)OC(C)=O.CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1C(F)(F)F>>CC(=O)N1CCC(n2cc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C(C)C(N)=O)n3)cn2)CC1 -US20100113780A1,1,CC(C)(C)CI.CCCc1nc(CC)c(-c2ccc(O)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(CC)c(-c2ccc(OCC(C)(C)C)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US20050203160A1,1,CCOC(=O)Cn1ccc2ccc(O)cc21.Cn1nc(-c2ccc(Cl)c(Cl)c2)cc1CO>>CCOC(=O)Cn1ccc2ccc(OCc3cc(-c4ccc(Cl)c(Cl)c4)nn3C)cc21 -US06713478B2,3,Nc1ccc(-c2cccc(Cl)c2)cc1C(=O)C1CC1.[Mg+]C1CC1>>Nc1ccc(-c2cccc(Cl)c2)cc1C(O)(C1CC1)C1CC1 -US20100152160A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CNc2cc(Cl)ccc2O1>>CCOC(=O)C1CN(C(=O)OC(C)(C)C)c2cc(Cl)ccc2O1 -US07378427B2,2,COc1ccc(S(=O)(=O)Cl)cc1.C[C@@H]1Nc2ccccc2-c2ccc(F)cc21>>COc1ccc(S(=O)(=O)N2c3ccccc3-c3ccc(F)cc3[C@@H]2C)cc1 -US06552086B1,2,CC(CS(=O)(=O)Cl)c1ccc(-c2ccccc2F)cc1.CN>>CNS(=O)(=O)CC(C)c1ccc(-c2ccccc2F)cc1 -US20010051632A1,6,COc1ccc(-c2cc3ccccn3c2C)c(C)c1>>Cc1cc(O)ccc1-c1cc2ccccn2c1C -US20080234282A1,6,COc1c(C#N)cc2ccccc2c1COCC(c1ccc(F)c(Cl)c1)N1CCN(C(=O)OC(C)(C)C)CC1>>COc1c(C#N)cc2ccccc2c1COCC(c1ccc(F)c(Cl)c1)N1CCNCC1 -US20090143364A1,2,CC(C)(C)c1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)Cl)c(OCCF)c1.CS(=O)(=O)CCN1CCNCC1>>CC(C)(C)c1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)N2CCN(CCS(C)(=O)=O)CC2)c(OCCF)c1 -US08962674B2,6,CC(C)(C)OC(=O)NCC(=O)Nc1ccc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)cc2)cc1>>NCC(=O)Nc1ccc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)cc2)cc1 -US09051321B2,9,ClC1(c2coc3ccccc23)CN(C(c2ccccc2)c2ccccc2)C1>>c1ccc(C(c2ccccc2)N2CC(c3coc4ccccc34)C2)cc1 -US20110263591A1,2,CC(C)C(=O)Cl.Nc1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1>>CC(C)C(=O)Nc1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1 -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1.COc1ccccc1C(=O)CCCCCBr>>COc1ccccc1C(=O)CCCCCN1CCC(CNC(=O)c2cc(Cl)c(N)cc2OC)CC1 -US04001218,2,Nc1ccc(C(=O)O)cc1.O=C(O)C1=CCCCC1>>O=C(Nc1ccc(C(=O)O)cc1)C1=CCCCC1 -US06982348B2,6,CCOC(=O)C(Cc1ccc(Oc2ccccc2)cc1)C(O)c1ccc(F)cc1>>O=C(O)C(Cc1ccc(Oc2ccccc2)cc1)C(O)c1ccc(F)cc1 -US07795282B2,6,Cc1nnc(N2N=C(c3cc(F)ccc3F)SC2(CCCNC(=O)OC(C)(C)C)c2cccc(O[Si](C)(C)C(C)(C)C)c2)s1>>Cc1nnc(N2N=C(c3cc(F)ccc3F)SC2(CCCNC(=O)OC(C)(C)C)c2cccc(O)c2)s1 -US08907094B2,2,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1.N[C@H]1CC[C@@H](Oc2ccc(C(=O)N3CCOCC3)nc2)c2ccccc21>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc(C(=O)N4CCOCC4)nc3)c3ccccc32)cc1 -US20070082907A1,2,COC(=O)CCc1ccc(Oc2cc(F)cc(C(C)N)c2)cc1C.COc1cc(C(F)(F)F)ccc1C(=O)O>>COC(=O)CCc1ccc(Oc2cc(F)cc([C@@H](C)NC(=O)c3ccc(C(F)(F)F)cc3OC)c2)cc1C -US04960758,3,COc1ccccc1Br.O=C(Cl)c1ccccc1Br>>COc1ccccc1C(=O)c1ccccc1Br -US20030225064A1,4,NNc1ccc(S(N)(=O)=O)c(F)c1.O=C(CC(=O)C(F)(F)F)c1ccc(-c2ccco2)c(Cl)c1>>NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3ccco3)c(Cl)c2)cc1F -US07301036B2,1,COC(=O)c1ccc(CBr)cc1.COc1ccc(Nc2nc3cc(Cl)c(Cl)cc3[nH]2)cc1>>COC(=O)c1ccc(Cn2c(Nc3ccc(OC)cc3)nc3cc(Cl)c(Cl)cc32)cc1 -US04992444,1,CCCCN.CCc1nc(N)nc(N)c1-c1ccc(Cl)c([N+](=O)[O-])c1>>CCCCNc1ccc(-c2c(N)nc(N)nc2CC)cc1[N+](=O)[O-] -US20090029947A1,7,COc1cccc(OCC(=O)O)c1>>COc1cccc(OCCO)c1 -US20070213355A1,7,N#CCc1ccc(-n2c(CCC(=O)O)nc3cnc4ccc(Br)cc4c32)cc1>>N#CCc1ccc(-n2c(CCCO)nc3cnc4ccc(Br)cc4c32)cc1 -US20090221551A1,7,CC(C)(C)OC(=O)NNc1c([N+](=O)[O-])cnc2ccccc12>>CC(C)(C)OC(=O)NNc1c(N)cnc2ccccc12 -US04066772,1,Cn1c(=O)n(CCCI)c2ccccc21.O=C1NCN(c2ccccc2)C12CCNCC2>>Cn1c(=O)n(CCCN2CCC3(CC2)C(=O)NCN3c2ccccc2)c2ccccc21 -US20100256165A1,6,CCOC(=O)Cc1nc(-c2ccc(F)cc2)oc1-c1cccc(OCc2ccccc2)c1>>CCOC(=O)Cc1nc(-c2ccc(F)cc2)oc1-c1cccc(O)c1 -US05138067,9,CCCCCCCCCCCCCCCCOCC(CC#N)CN=[N+]=[N-]>>CCCCCCCCCCCCCCCCOCC(CN)CC#N -US07494986B2,8,OC1CCCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1>>O=C1CCCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1 -US08163737B2,1,CC(C)(C)CCN.O=Cc1cccc(F)c1N1CCC(F)C1>>CC(C)(C)CCN=Cc1cccc(F)c1N1CCC(F)C1 -US20120309789A1,7,CO[C@@H]1CC[C@H](N2CCC(Nc3cc(C)c(Cl)cc3[N+](=O)[O-])CC2)CC1>>CO[C@@H]1CC[C@H](N2CCC(Nc3cc(C)c(Cl)cc3N)CC2)CC1 -US20110178064A1,3,C[C@H]1CN(c2ncc(Br)cc2C=O)C[C@@H](C)O1.OB(O)c1ccccc1>>C[C@H]1CN(c2ncc(-c3ccccc3)cc2C=O)C[C@@H](C)O1 -US20030176454A1,1,Cc1ncc(-c2cccc(N)c2)n1C.Fc1ccc(Cc2nnc(Cl)c3ccccc23)cc1>>Cc1ncc(-c2cccc(Nc3nnc(Cc4ccc(F)cc4)c4ccccc34)c2)n1C -US04436748,6,COc1cc2cc(-c3ccccc3C)sc2c(Cl)c1Cl>>Cc1ccccc1-c1cc2cc(O)c(Cl)c(Cl)c2s1 -US20150152113A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Fc1cc(Br)c(OC(F)F)cc1F>>CC(C)(C)OC(=O)N1CC=C(c2cc(F)c(F)cc2OC(F)F)CC1 -US06093718,1,Clc1cc(Cl)ncn1.c1ccc(CN2CCNCC2)cc1>>Clc1cc(N2CCN(Cc3ccccc3)CC2)ncn1 -US20150191495A1,3,Cc1cc(OCCCS(C)(=O)=O)ncc1Br.O=C(O)c1cc(B(O)O)ccc1F>>Cc1cc(OCCCS(C)(=O)=O)ncc1-c1ccc(F)c(C(=O)O)c1 -US04340758,7,Cc1cc(C(C)(C)C)cc(C)c1[N+](=O)[O-]>>Cc1cc(C(C)(C)C)cc(C)c1N -US04521428,1,Cc1cccc(CCCl)n1.FC(F)(F)c1cccc(C2=CCNCC2)c1>>Cc1cccc(CCN2CC=C(c3cccc(C(F)(F)F)c3)CC2)n1 -US20050261333A1,7,O=[N+]([O-])c1cc(-c2nc3ncc(Cl)c(Cl)c3[nH]2)ccc1OCCN1CCOCC1>>Nc1cc(-c2nc3ncc(Cl)c(Cl)c3[nH]2)ccc1OCCN1CCOCC1 -US20140199263A1,7,Oc1ccc(Cl)nc1-c1cc2c(F)cccc2[nH]1>>Oc1ccc(Cl)nc1C1Cc2c(F)cccc2N1 -US04734425,2,NCC(=O)O.O=C(Cl)COc1ccccc1>>O=C(O)CNC(=O)COc1ccccc1 -US07470712B2,9,CC(C)(C)c1ccccc1Oc1nc(Br)ccc1N.[C-]#N>>CC(C)(C)c1ccccc1Oc1nc(C#N)ccc1N -US20100197591A1,6,COC(=O)CC1CCC(c2ccc(N3CCc4nc(C)nc(N)c4C3=O)cc2)CC1>>Cc1nc(N)c2c(n1)CCN(c1ccc(C3CCC(CC(=O)O)CC3)cc1)C2=O -US20050256180A1,6,C=CCN(C(C)=O)S(=O)(=O)c1ccc(-n2nc(C(N)=O)c3c2-c2cc(NC(=O)c4ccccc4Cl)ccc2CC3)cc1>>C=CCNS(=O)(=O)c1ccc(-n2nc(C(N)=O)c3c2-c2cc(NC(=O)c4ccccc4Cl)ccc2CC3)cc1 -US20070232627A1,7,CCOC(=O)[C@](C)(N)c1ccccc1>>C[C@](N)(CO)c1ccccc1 -US20150025087A1,2,COc1ncnc(Cn2cc(C(=O)O)c3ncc(C)cc32)c1C.NCC(F)F>>COc1ncnc(Cn2cc(C(=O)NCC(F)F)c3ncc(C)cc32)c1C -US20110021500A1,2,CC1Cc2ccccc2N1.O=C(O)c1ccnc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)c1>>CC1Cc2ccccc2N1C(=O)c1ccnc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)c1 -US08288402B2,1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(=O)[O-])N(C)C(=O)N1c1cccc(C(F)(F)F)c1.ClCc1cscn1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(=O)(=O)Cc2cscn2)N(C)C(=O)N1c1cccc(C(F)(F)F)c1 -US06797826B2,7,CC(C)(C(=O)O)c1ccc(C(=O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1>>CC(C)(C(=O)O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 -US05849736,9,N#Cc1ccc(C=O)cc1.NO>>N#Cc1ccc(C=NO)cc1 -US20140094462A1,2,CC(=O)OC(C)=O.N[C@H]1CC=CC[C@@H](CC(=O)NCc2ccc(Cl)cc2)C(=O)N2CCC[C@H]2COC1=O>>CC(=O)N[C@H]1CC=CC[C@@H](CC(=O)NCc2ccc(Cl)cc2)C(=O)N2CCC[C@H]2COC1=O -US05032165,1,CCOC(=O)C(C)Br.CSc1c(Cl)c(-c2cc(O)c(Cl)cc2Cl)nn1C>>CCOC(=O)C(C)Oc1cc(-c2nn(C)c(SC)c2Cl)c(Cl)cc1Cl -US09150592B2,2,Cc1nn(C)c2c1C(c1ccc(Cl)cc1Cl)SC(C)(C)CN2.O=CO>>Cc1nn(C)c2c1C(c1ccc(Cl)cc1Cl)SC(C)(C)CN2C=O -US08278442B2,1,N#Cc1ccc(B(O)O)cc1.O=Cc1ccc(O)c2ccccc12>>N#Cc1ccc(Oc2ccc(C=O)c3ccccc23)cc1 -US07781435B2,7,COC(=O)C1CCC1n1cnc([N+](=O)[O-])c1>>O=[N+]([O-])c1cn(C2CCC2CO)cn1 -US06924391B2,2,CC(C)(C)OC(=O)c1ccc(OCC(=O)C(C)(C)Oc2ccc(CCCO)cc2)cc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)c1ccc(OCC(=O)C(C)(C)Oc2ccc(CCCOS(C)(=O)=O)cc2)cc1 -US20040127502A1,1,Nc1ccc2[nH]ccc2c1.O=C1C(=O)N(c2ccccc2)c2ccccc21>>O=C1C(=Nc2ccc3[nH]ccc3c2)c2ccccc2N1c1ccccc1 -US06143769,2,CCCC(N)c1ccccc1N1CCCCC1.COC(=O)c1ccc(CC(=O)O)c(OC)c1>>CCCC(NC(=O)Cc1ccc(C(=O)OC)cc1OC)c1ccccc1N1CCCCC1 -US05789412,2,O=C(Cl)CCl.c1ccc2c(N3CCNCC3)cccc2c1>>O=C(CCl)N1CCN(c2cccc3ccccc23)CC1 -US20040010009A1,2,CC(C)(C)OC(=O)N1CCC(Oc2ccc(N)cc2)CC1.CCS(=O)(=O)Cl>>CCS(=O)(=O)Nc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20150111892A1,2,CCCCCCN=C=O.O=c1[nH]cc(-c2ccccc2)c(=O)[nH]1>>CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O -US20100113465A1,9,CC(C)(C)OC(=O)N1CCC2(CC1)CC(C(=O)O)C2.N>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(C(N)=O)C2 -US04885246,8,CCOC(=O)[C@@H]1[C@@H]2CC3(C[C@@H]2C[C@@H]1O)OCCO3>>CCOC(=O)C1C(=O)C[C@H]2CC3(C[C@@H]12)OCCO3 -US07642270B2,2,CC(C)(C)OC(=O)Nc1ccc(C2CCNCC2)cc1.CN(C)CC(=O)Cl>>CN(C)CC(=O)N1CCC(c2ccc(NC(=O)OC(C)(C)C)cc2)CC1 -US20100216813A1,1,Cc1cc(C=O)n(C)n1.Cc1ccccc1CN(c1ccc(C#N)c(Cl)c1)[C@H]1CCNC1>>Cc1cc(CN2CC[C@H](N(Cc3ccccc3C)c3ccc(C#N)c(Cl)c3)C2)n(C)n1 -US20150018363A1,1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1ccsc1Cl>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccsc4Cl)cc3=O)cc21 -US04788214,1,CCCc1c(O)ccc(C(C)=O)c1O.CCCc1c2c(cc(C(C)=O)c1OCCCBr)CCC(C)(CCC(=O)OCC)O2>>CCCc1c(OCCCOc2c(C(C)=O)cc3c(c2CCC)OC(C)(CCC(=O)OCC)CC3)ccc(C(C)=O)c1O -US20090227566A1,6,COCOc1cc(C(C)C)ccc1C(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1>>CC(C)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)c(O)c1 -US09018214B2,3,C=C(C)B1OC(C)(C)C(C)(C)O1.CC(C)(C)OC(=O)N1CC(C)(C)c2cnc(Cl)cc21>>C=C(C)c1cc2c(cn1)C(C)(C)CN2C(=O)OC(C)(C)C -US20130109661A1,2,COc1ccc(Nc2cc(-c3ccc(C(=O)O)cc3)nn3ccnc23)nc1OC.NCCc1ccncc1>>COc1ccc(Nc2cc(-c3ccc(C(=O)NCCc4ccncc4)cc3)nn3ccnc23)nc1OC -US20060247439A1,1,NCCCNc1ccc2ccccc2n1.O=Cc1ccoc1>>c1ccc2nc(NCCCNCc3ccoc3)ccc2c1 -US20150073139A1,2,CCC(=O)O.NCc1sc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F>>CCC(=O)NCc1sc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F -US04396553,8,CCc1cc(C=C(C)c2ccc3c(c2)C(C)(C)CCC3(C)C)ccc1Sc1ccc(C=C(C)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1CC.O=C(OO)c1cccc(Cl)c1>>CCc1cc(C=C(C)c2ccc3c(c2)C(C)(C)CCC3(C)C)ccc1S(=O)c1ccc(C=C(C)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1CC -US20140274703A1,3,COC(=O)c1nc(Cl)cc(NC(C)=O)c1Cl.Cc1c(B2OCC(C)(C)CO2)ccc([Si](C)(C)c2ccccc2)c1F>>COC(=O)c1nc(-c2ccc([Si](C)(C)c3ccccc3)c(F)c2C)cc(NC(C)=O)c1Cl -US07595327B2,6,COC(=O)[C@@]1(C)COCC[C@H]1NS(=O)(=O)c1ccc(OCc2ccccc2)cc1>>C[C@]1(C(=O)O)COCC[C@H]1NS(=O)(=O)c1ccc(OCc2ccccc2)cc1 -US20150158863A1,6,COc1cnc2c(c1)NC(=O)CN2C(=O)OCc1ccccc1>>COc1cnc2c(c1)NC(=O)CN2 -US06197804B1,7,Cc1nc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(N)c21>>Cc1nc[nH]c1/C=C1\C(=O)Nc2ccc(N)c(N)c21 -US20080275029A1,6,O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(C(=O)Nc2ccc3c(=O)[nH]cnc3c2)(c2ccc(Cl)cc2)CC1>>O=C(Nc1ccc2c(=O)[nH]cnc2c1)C1(c2ccc(Cl)cc2)CCNCC1 -US20070004700A1,9,CCOC(=O)c1csc(N)n1.ICI>>CCOC(=O)c1csc(I)n1 -US05344843,6,COC(=O)C(=O)c1ccc(OCCOc2ccc(Cl)cc2)cc1>>O=C(O)C(=O)c1ccc(OCCOc2ccc(Cl)cc2)cc1 -US05925789,1,COc1ccc(CO)cc1OC.Nc1ccc(Cl)cc1C(=O)C(F)(F)F>>COc1ccc(CNc2ccc(Cl)cc2C(=O)C(F)(F)F)cc1OC -US20050059632A1,6,OC1C[C@@H](O)[C@H](COCc2ccccc2)O1>>OC[C@@H]1OC(O)C[C@H]1O -US20060035912A1,2,CC(C)n1cc(C(=O)c2cc(N)ccn2)c2c(N)ncnc21.O=S(=O)(Cl)c1ccccc1F>>CC(C)n1cc(C(=O)c2cc(NS(=O)(=O)c3ccccc3F)ccn2)c2c(N)ncnc21 -US20100324030A1,2,COc1cnc2cccc(OCCN3CCNCC3)c2c1.O=C1CSc2ccc(S(=O)(=O)Cl)cc2N1>>COc1cnc2cccc(OCCN3CCN(S(=O)(=O)c4ccc5c(c4)NC(=O)CS5)CC3)c2c1 -US06660752B2,3,CC(C)(C)OC(=O)NC[C@H]1CCc2cc(I)ccc2O1.COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>COC(=O)c1ccc(-c2ccc3c(c2)CC[C@H](CNC(=O)OC(C)(C)C)O3)cc1 -US20120190677A1,6,COC(=O)c1cc(F)cc2c1NC(c1cccc(N3CCCC3)c1)CC2(C)C>>CC1(C)CC(c2cccc(N3CCCC3)c2)Nc2c(C(=O)O)cc(F)cc21 -US20110086853A1,2,CC(C)N.O=C(O)c1cc[nH]c1>>CC(C)NC(=O)c1cc[nH]c1 -US08309718B2,7,O=C1OCCCN1c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2CCCOC2=O)cc1 -US20130059849A1,2,COc1ccc(-c2cc(C(=O)O)c3cnn(C(C)C)c3n2)cc1.Cc1cc(C)c(CN)c(=O)[nH]1>>COc1ccc(-c2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c3cnn(C(C)C)c3n2)cc1 -US20120178736A1,1,CC(C)(O)C1CCCNC1.Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)sc2n1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCCC(C(C)(C)O)C3)sc2n1 -US20090131431A1,4,CCn1ncc2c(NC3CCOCC3)c(CN)c(C)nc21.O=C(Cl)CCCCCl>>CCn1ncc2c(NC3CCOCC3)c(CN3CCCCC3=O)c(C)nc21 -US20110098301A1,2,CNCCOC.Nc1nc(Nc2ccc(Oc3ccnc(C(=O)O)c3)cc2)cc(-c2ccccc2)n1>>COCCN(C)C(=O)c1cc(Oc2ccc(Nc3cc(-c4ccccc4)nc(N)n3)cc2)ccn1 -US06211373B1,7,O=[N+]([O-])c1cc(Cl)cc(Cl)c1O>>Nc1cc(Cl)cc(Cl)c1O -US04082843,1,CI.COC(=O)CCC(=O)c1cccc(OC(C)=O)c1O>>COC(=O)CCC(=O)c1cccc(OC(C)=O)c1OC -US20020045777A1,2,CN[C@@H]1CC[C@@H](OCCCCBr)CC1.O=S(=O)(Cl)c1ccc(F)cc1F>>CN([C@@H]1CC[C@@H](OCCCCBr)CC1)S(=O)(=O)c1ccc(F)cc1F -US20040209921A1,1,CC(C)(C)OC(=O)NCCCCN.Cn1c(C=O)nc2ccccc21>>Cn1c(CNCCCCNC(=O)OC(C)(C)C)nc2ccccc21 -US20090111794A1,1,NC(=O)N1C[C@@H]2C[C@H]1CN2.O=Cc1ccc(Oc2nc3ccccc3s2)cc1>>NC(=O)N1C[C@@H]2C[C@H]1CN2Cc1ccc(Oc2nc3ccccc3s2)cc1 -US05688809,1,Cc1ccc(F)c([N+](=O)[O-])c1.Nc1ccc2[nH]ccc2c1>>Cc1ccc(Nc2ccc3[nH]ccc3c2)c([N+](=O)[O-])c1 -US20130085148A1,7,CCOC(=O)c1cc(-c2ccc(F)cc2)n[nH]1>>OCc1cc(-c2ccc(F)cc2)n[nH]1 -US20090253689A1,3,CC(C)COc1c(C#N)c(-c2ccc(Cl)cc2Cl)cn2c(Br)cnc12.OB(O)c1ccc(F)nc1>>CC(C)COc1c(C#N)c(-c2ccc(Cl)cc2Cl)cn2c(-c3ccc(F)nc3)cnc12 -US20140296203A1,1,COC/C=C/c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)ncc12.C[C@@H](NC(N)=O)c1ccccc1>>COC/C=C/c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(NC(=O)N[C@H](C)c3ccccc3)ncc12 -US20100249089A1,1,O=Cc1ccc(Br)s1.OC1CCNCC1>>O=Cc1ccc(N2CCC(O)CC2)s1 -US20050282862A1,2,CC(C)(C)c1ccc(C(=O)Cl)cc1.COC(=O)c1ccccc1N>>COC(=O)c1ccccc1NC(=O)c1ccc(C(C)(C)C)cc1 -US07595397B2,1,CI.O=C(c1ccc(-c2ccccc2C(F)(F)F)cc1)N1CCNC(c2ccccc2)C1>>CN1CCN(C(=O)c2ccc(-c3ccccc3C(F)(F)F)cc2)CC1c1ccccc1 -US05679700,1,BrCC=CCBr.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CC=CCBr -US05260318,7,CN(CCc1ccc([N+](=O)[O-])cc1)C1CCN(c2ccc(C#N)cc2)CC1>>CN(CCc1ccc(N)cc1)C1CCN(c2ccc(C#N)cc2)CC1 -US07435815B2,2,CCNCc1ncc[nH]1.Cc1ccc(N(CC(=O)O)S(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1>>CCN(Cc1ncc[nH]1)C(=O)CN(c1ccc(C)cc1)S(=O)(=O)c1ccc(C(C)(C)C)cc1 -US20150158846A1,3,CC#CC(=O)NCCOc1cccc(Nc2cc(Br)cn(C)c2=O)n1.CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cc(F)cc1-n1ncc2c3c(sc2c1=O)CCCC3>>CC#CC(=O)NCCOc1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3COC(C)=O)cn(C)c2=O)n1 -US20150246912A1,1,CON(C)C(=O)c1cncc(Br)c1.N=C(c1ccccc1)c1ccccc1>>CON(C)C(=O)c1cncc(N=C(c2ccccc2)c2ccccc2)c1 -US05840751,1,CC(C)CCC1(c2ccccc2)CC(O)=C(Br)C(=O)O1.COC(=O)c1ccccc1S>>COC(=O)c1ccccc1SC1=C(O)CC(CCC(C)C)(c2ccccc2)OC1=O -US20110263588A1,8,Cn1nc(CO)c2c1-c1ccccc1OC2>>Cn1nc(C=O)c2c1-c1ccccc1OC2 -US20120270875A1,7,CCOC(=O)c1c(C)nc(NC/C=C/c2ccc(C)c(O)c2)nc1C>>CCOC(=O)c1c(C)nc(NCCCc2ccc(C)c(O)c2)nc1C -US08222411B2,1,Cn1c(=O)cc(Cl)[nH]c1=O.N#Cc1ccc(F)cc1CBr>>Cn1c(=O)cc(Cl)n(Cc2cc(F)ccc2C#N)c1=O -US20090099161A1,3,C=CN1C(=O)c2ccccc2C1=O.COCCc1nc2cnc3ccc(Br)cc3c2n1CCCN1CCCC1=O>>COCCc1nc2cnc3ccc(C=CN4C(=O)c5ccccc5C4=O)cc3c2n1CCCN1CCCC1=O -US20110053897A1,1,Cc1cc(N)ccc1C1CCN(C(=O)OC(C)(C)C)CC1.O=c1[nH]ccc2cc(Cl)nc(Cl)c12>>Cc1cc(Nc2nc(Cl)cc3cc[nH]c(=O)c23)ccc1C1CCN(C(=O)OC(C)(C)C)CC1 -US20090325930A1,7,CCN(C(=O)c1ccncc1)c1cc(OC)ccc1C1CCc2cc(OC)ccc2C1>>CCN(Cc1ccncc1)c1cc(OC)ccc1C1CCc2cc(OC)ccc2C1 -US20120035370A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC[C@H](N)c1ccnc(C(N)=O)c1>>CC[C@H](NC(=O)OC(C)(C)C)c1ccnc(C(N)=O)c1 -US20050090485A1,2,CC(C)(C)OC(=O)N1CCc2ccc(N)cc2CC1.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCc2ccc(NS(=O)(=O)c3ccccc3)cc2CC1 -US08404859B2,6,COC(=O)[C@H](CNC(=O)c1cccs1)NC(=O)c1sc(C(=O)NCc2cccc(O)c2)cc1C(F)(F)F>>O=C(NC[C@H](NC(=O)c1sc(C(=O)NCc2cccc(O)c2)cc1C(F)(F)F)C(=O)O)c1cccs1 -US20100279936A1,1,C[C@@H](N)c1cccc2ccccc12.O=Cc1cc(C#CCO)cs1>>C[C@@H](NCc1cc(C#CCO)cs1)c1cccc2ccccc12 -US05106851,6,CCOC(=O)C1Cc2ccc(Cl)cc2NC1=O>>O=C(O)C1Cc2ccc(Cl)cc2NC1=O -US04636513,2,C1CCNCC1.CCCc1oncc1C(=O)O>>CCCc1oncc1C(=O)N1CCCCC1 -US08680091B2,6,CC(C)(C)OC(=O)NCc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1>>CC1(C)C(C(=O)Nc2ccc(CN)cc2)C1(C)C -US20100120785A1,1,Cc1nn(C)c(C)c1C=O.Clc1nccnc1N1CCNCC1>>Cc1nn(C)c(C)c1CN1CCN(c2nccnc2Cl)CC1 -US20120202837A1,5,O=Cc1cc(F)c(F)cc1Br.OCCO>>Fc1cc(Br)c(C2OCCO2)cc1F -US05445762,2,C1COCCOCCOCCOCCOCCOCCN1.CCC(C)(C)C(=O)Cl>>CCC(C)(C)C(=O)N1CCOCCOCCOCCOCCOCCOCC1 -US20120022044A1,1,Clc1ccncn1.O=C1C(n2cc(C3CCNCC3)nn2)CCc2c(F)cccc2N1CC(F)(F)F>>O=C1C(n2cc(C3CCN(c4ccncn4)CC3)nn2)CCc2c(F)cccc2N1CC(F)(F)F -US08461330B2,1,Fc1cc(Br)ccc1CBr.c1cn[nH]c1>>Fc1cc(Br)ccc1Cn1cccn1 -US20150191478A1,1,Brc1ccncc1.CCOC(OCC)c1cc2cncc(-c3cccc(O)c3)c2o1>>CCOC(OCC)c1cc2cncc(-c3cccc(Oc4ccncc4)c3)c2o1 -US06838463B2,1,CC#CC(C)O.Fc1cccc(-c2cc(Cl)ncn2)c1F>>CC#CC(C)Oc1cc(-c2cccc(F)c2F)ncn1 -US04168385,10,COC(=O)Cc1ccc(Oc2ccc(S(C)(=O)=O)cc2)cc1.O=C1CCC(=O)N1Br>>COC(=O)C(Br)c1ccc(Oc2ccc(S(C)(=O)=O)cc2)cc1 -US20110028469A1,2,COC(=O)c1sccc1N.O=S(=O)(Cl)c1ccc(F)cc1>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(F)cc1 -US20090062530A1,6,COC(=O)CCc1cc(NC(=O)C(F)(F)F)c(OCc2ccccc2)c(-c2ccc3ccccc3c2)c1>>COC(=O)CCc1cc(NC(=O)C(F)(F)F)c(O)c(-c2ccc3ccccc3c2)c1 -US20080255152A1,1,ClCCN1CCOCC1.NC(=O)c1ccc(Oc2ccc3c(c2)CCCNC3)nc1>>NC(=O)c1ccc(Oc2ccc3c(c2)CCCN(CCN2CCOCC2)C3)nc1 -US20140179672A1,2,Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)O)n2c1.NC1CC(N)C1>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NC3CC(N)C3)n2c1 -US05068325,1,Cc1ccc(C=CCCl)cc1.Nc1nc2c(s1)CCNCC2>>Cc1ccc(C=CCN2CCc3nc(N)sc3CC2)cc1 -US20100130538A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1cccc2nscc12>>CCOC(=O)/C=C/c1cccc2nscc12 -US04820821,1,N=c1ccn(-c2ccccc2)nc1.O=C(Cl)c1ccccc1>>O=C(N=c1ccn(-c2ccccc2)nc1)c1ccccc1 -US20150038488A1,1,C[Si](C)(C)CCOCCl.O=C1Nc2cc(Br)ccc2C1(F)F>>C[Si](C)(C)CCOCN1C(=O)C(F)(F)c2ccc(Br)cc21 -US20130289033A1,3,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1.OB(O)c1ccccc1Cl>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(-c2ccccc2Cl)c1 -US04782176,1,CCCc1c(OCCCCCC(=O)OC)ccc(C(C)=O)c1O.CS(=O)(=O)OCCOCCOS(C)(=O)=O>>CCCc1c(OCCCCCC(=O)OC)ccc(C(C)=O)c1OCCOCCOS(C)(=O)=O -US20120040948A1,6,CCOC(=O)NC1Cc2ccc(OC)cc2C1Cc1ccccc1>>CCOC(=O)NC1Cc2ccc(O)cc2C1Cc1ccccc1 -US20100278833A1,9,COC(=O)c1sc(-n2cnc3cnc(Cl)cc32)cc1OCc1ccccc1C(F)(F)F.N>>NC(=O)c1sc(-n2cnc3cnc(Cl)cc32)cc1OCc1ccccc1C(F)(F)F -US20010051631A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cn2c(CNCCCCNS(=O)(=O)C(F)(F)F)cccc2n1>>Cc1cn2c(CN(CCCCNS(=O)(=O)C(F)(F)F)C(=O)OC(C)(C)C)cccc2n1 -US20110263628A1,1,C[C@@H]1CNCCN1.FC(F)(F)c1ccc(Br)nc1>>C[C@@H]1CN(c2ccc(C(F)(F)F)cn2)CCN1 -US20050192325A1,2,CC(C)OC(=O)Cl.Nc1cc(F)cc(F)c1>>CC(C)OC(=O)Nc1cc(F)cc(F)c1 -US20090030015A1,2,COC(=O)c1cccc(N)c1.COc1ccc(-c2cccc(C(=O)Cl)c2)c(OC)c1>>COC(=O)c1cccc(NC(=O)c2cccc(-c3ccc(OC)cc3OC)c2)c1 -US07851473B2,2,Cc1ccc(N=C=O)cc1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>Cc1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)cc1 -US20150158865A1,1,BrCCBr.Nc1cccc(Cl)c1>>Clc1cccc(NCCBr)c1 -US20040186151A1,1,CCCCn1cc(-c2ccc(Cl)cc2Cl)nc1[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C.COC(=O)c1ccc(I)cc1>>CCCCn1cc(-c2ccc(Cl)cc2Cl)nc1[C@H](Cc1ccc(Oc2ccc(C(=O)OC)cc2)cc1)NC(=O)OC(C)(C)C -US20050245529A1,1,CC(N)(CO)CO.ClC/C=C/c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1>>CC(CO)(CO)NC/C=C/c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1 -US20100280013A1,5,C/C=C\c1cc(C(O)(C(F)(F)F)C(F)(F)F)ccc1N1CCN(CCOCc2ccccc2)CC1.COCCl>>C/C=C\c1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1N1CCN(CCOCc2ccccc2)CC1 -US20080207648A1,3,C#CCCCC.COc1ccc(C(Nc2nc(Cl)nc3c2ncn3[C@@H]2C[C@H](n3cc(C)cn3)[C@@H](O)[C@H]2O)c2ccc(OC)cc2)cc1>>CCCCC#Cc1nc(NC(c2ccc(OC)cc2)c2ccc(OC)cc2)c2ncn([C@@H]3C[C@H](n4cc(C)cn4)[C@@H](O)[C@H]3O)c2n1 -US20140288347A1,9,CC(=O)c1cccc(C(=O)O)c1.NO>>CC(=NO)c1cccc(C(=O)O)c1 -US20140249119A1,2,CNCCC(=O)OC(C)(C)C.C[C@]12CC[C@@H]3c4ccc(C(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1>>CN(CCC(=O)OC(C)(C)C)C(=O)c1ccc2c(c1)CC[C@H]1[C@@H]3CC=C(c4cncc(F)c4)[C@@]3(C)CC[C@H]21 -US04810721,1,COc1ccc(O)cc1.O=C([C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1)N1CCCC1>>COc1ccc(O[C@H]2C[C@@H](C(=O)N3CCCC3)N(C(=O)OCc3ccccc3)C2)cc1 -US08293772B2,1,Cc1ccc([N+](=O)[O-])cc1C(=O)c1ccc(Br)cc1Cl.Nc1ccc(F)cc1Cl>>Cc1ccc([N+](=O)[O-])cc1C(=O)c1ccc(Nc2ccc(F)cc2Cl)cc1Cl -US20090137562A1,6,CC(C)N1CCN(Cc2ccc(F)c(C3OCCO3)c2)CC1>>CC(C)N1CCN(Cc2ccc(F)c(C=O)c2)CC1 -US05665718,6,CCCN(CCC)Cc1nc(CN2C(=O)c3ccccc3C2=O)no1>>CCCN(CCC)Cc1nc(CN)no1 -US04426222,2,N#CCCNc1ccccc1.O=C(Cl)Oc1cccc(NC(=O)C2CC2)c1>>N#CCCN(C(=O)Oc1cccc(NC(=O)C2CC2)c1)c1ccccc1 -US20040176383A1,1,Cc1nc2cc(OC[C@H](O)CN3CCNCC3)ccc2s1.Fc1cccc(-c2noc(CCl)n2)c1>>Cc1nc2cc(OC[C@H](O)CN3CCN(Cc4nc(-c5cccc(F)c5)no4)CC3)ccc2s1 -US20150038528A1,2,CCOC(=O)c1ncc2cc(NC(=O)Nc3ccccc3)ccc2c1O.NC[C@H](O)C(=O)O>>O=C(Nc1ccccc1)Nc1ccc2c(O)c(C(=O)NC[C@H](O)C(=O)O)ncc2c1 -US20090181962A1,2,COc1cccc(-c2cc(N)c(C(N)=O)s2)c1.C[Si](C)(C)N=C=O>>COc1cccc(-c2cc(NC(N)=O)c(C(N)=O)s2)c1 -US04910218,7,CCOC(=O)c1cc2ccc3ccc4ccccc4c3c2o1>>OCc1cc2ccc3ccc4ccccc4c3c2o1 -US20150191495A1,1,CCOC(=O)C1C2Cc3cc(O)ncc3C21.Cc1cccc(C)c1-c1ccc(F)c(CBr)n1>>CCOC(=O)C1C2Cc3cc(OCc4nc(-c5c(C)cccc5C)ccc4F)ncc3C21 -US20120289505A1,2,COC(=O)C1(N2Cc3ccc(-c4ccc(N)cc4)cc3C2=O)CCC1.O=C(Cl)c1ccc(Cl)cc1>>COC(=O)C1(N2Cc3ccc(-c4ccc(NC(=O)c5ccc(Cl)cc5)cc4)cc3C2=O)CCC1 -US20140343019A1,6,COC1(OC)CC(C(CCCCB2OC(C)(C)C(C)(C)O2)(NC(C)=O)C(=O)NC(C)(C)C)C1>>CC(=O)NC(CCCCB1OC(C)(C)C(C)(C)O1)(C(=O)NC(C)(C)C)C1CC(=O)C1 -US07176231B2,3,CC(=O)c1ccc2c(c1)CC(=O)N2C(C)=O.O=C(O)c1ccc(Cl)c(Cl)c1>>CC(=O)c1ccc2c(c1)C(=C(O)c1ccc(Cl)c(Cl)c1)C(=O)N2C(C)=O -US07968570B2,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.ClCc1ccncc1>>CC1(C)OB(c2cnn(Cc3ccncc3)c2)OC1(C)C -US06897231B2,3,COc1ccc(B(O)O)cc1.N#Cc1ccc2c(c1)c(Br)nn2C1CCCCO1>>COc1ccc(-c2nn(C3CCCCO3)c3ccc(C#N)cc23)cc1 -US20080070974A1,1,O=C(O)CC(=O)CCl.O=C(O)CS>>O=C(O)CSCC(=O)CC(=O)O -US06147097,2,CC(=O)Cl.Cc1cc(C)cc(Sc2[nH]c(C)nc2CO)c1>>CC(=O)OCc1nc(C)[nH]c1Sc1cc(C)cc(C)c1 -US07507841B2,7,CC(=O)Oc1c(C)c2c(-c3ccc(C(C)C)cc3)coc2c2ccccc12>>CC(=O)Oc1c(C)c2c(c3ccccc13)OCC2c1ccc(C(C)C)cc1 -US20030139416A1,7,O=[N+]([O-])c1ccc2c(cnn2Cc2ccccn2)c1>>Nc1ccc2c(cnn2Cc2ccccn2)c1 -US05919824,2,CNc1cccc(C)c1C.O=C(Br)CBr>>Cc1cccc(N(C)C(=O)CBr)c1C -US07705004B2,1,Cc1ccc(S(=O)(=O)n2ccc3c(Nc4ccc5cnn(C)c5c4)nc(Cl)nc32)cc1.NC(=O)c1ccc(N)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4ccc5cnn(C)c5c4)nc(Nc4ccc(C(N)=O)cc4)nc32)cc1 -US08802684B2,1,CCCCOc1nc(N)c2nc(OC)[nH]c2n1.O=C(OCc1ccccc1)N1CCCC(CCBr)C1>>CCCCOc1nc(N)c2nc(OC)n(CCC3CCCN(C(=O)OCc4ccccc4)C3)c2n1 -US20040162303A1,1,CC[C@@H](N)CO.COc1ccc(F)cc1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N>>CC[C@H](CO)NCCCS(=O)(=O)N1CCC(Nc2ncc(C(=O)c3cc(F)ccc3OC)c(N)n2)CC1 -US04024147,1,O=C(NC1CCNCC1)c1ccccc1.OCCBr>>O=C(NC1CCN(CCO)CC1)c1ccccc1 -US08796296B2,7,COc1c([N+](=O)[O-])ccc2c1CN(C)C2=O>>COc1c(N)ccc2c1CN(C)C2=O -US07214673B2,1,C=O.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN[C@@H](CCc2ccoc2)C1>>Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)[C@@H](CCc2ccoc2)C1 -US04501912,2,O=C(Cl)c1ccccc1F.OCC1CO1>>O=C(OCC1CO1)c1ccccc1F -US06156700,10,Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(CCl)c3c2)c1=O.O=C1CCC(=O)N1Br>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(C(Cl)Br)c3c2)c1=O -US06288228B1,2,C1CCNCC1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>N#Cc1ccc(S(=O)(=O)N2CCCCC2)cc1 -US20070225290A1,1,CC[C@H](C[C@@](O)(C=O)C(F)(F)F)c1ccc(F)c(F)c1OC.Nc1cccc2c(=O)[nH]ncc12>>CC[C@H](C[C@@](O)(C=Nc1cccc2c(=O)[nH]ncc12)C(F)(F)F)c1ccc(F)c(F)c1OC -US03963718,1,CC(NC1=NCCN1)C(O)c1ccccc1>>CC1NC2=NCCN2C1c1ccccc1 -US20120302596A1,2,C1=C(c2c[nH]c3ncccc23)CC2CCCN2C1.COc1cccc(OC)c1C(=O)Cl>>COc1cccc(OC)c1C(=O)n1cc(C2=CCN3CCCC3C2)c2cccnc21 -US07557213B2,3,COCCOc1ccc(I)cc1C.CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O>>COCCOc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1C -US20080261941A1,2,Nc1ccnnc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccnnc1)Oc1ccccc1 -US20040034096A1,6,C[Si](C)(C)C#Cc1ccc(OCc2cccc(F)c2)cc1>>C#Cc1ccc(OCc2cccc(F)c2)cc1 -US20120302566A1,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)cccc43)ccc21.Clc1cccc(Cl)c1I>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(Cl)cccc5Cl)cccc43)ccc21 -US20120015942A1,6,COC(=O)C1CCc2ccc(-c3cccc(OCc4ccccc4)c3)cc2C1>>COC(=O)C1CCc2ccc(-c3cccc(O)c3)cc2C1 -US20060116410A1,2,CNC(=O)COc1cc(C#N)ccc1CN.O=C(O)c1cc(Cl)ccc1O>>CNC(=O)COc1cc(C#N)ccc1CNC(=O)c1cc(Cl)ccc1O -US08815864B2,1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(O)ccc(F)c43)ccc21.Cc1cccc(C)c1B(O)O>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5c(C)cccc5C)ccc(F)c43)ccc21 -US20130072492A1,10,COC(=O)C(C)c1cnccn1.O=C1CCC(=O)N1Br>>COC(=O)C(C)(Br)c1cnccn1 -US07968568B2,6,CC(C)(C)OC(=O)N1CCC(Nc2nc(Cl)ncc2F)CC1>>Fc1cnc(Cl)nc1NC1CCNCC1 -US20100273816A1,1,CCS(=O)(=O)c1cc(F)cc(F)c1.Oc1ccc(Cl)c(-c2ncnc3c(C(F)(F)F)cccc23)c1>>CCS(=O)(=O)c1cc(F)cc(Oc2ccc(Cl)c(-c3ncnc4c(C(F)(F)F)cccc34)c2)c1 -US20040242573A1,1,BrCC1CCCO1.Oc1ccc(Br)cc1>>Brc1ccc(OCC2CCCO2)cc1 -US20140378457A1,1,CC1(C)CC=C(c2nc(C3(O)CCOCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1.CN1CCNCC1>>CN1CCN(C2(c3ccc(NC(=O)c4nc(C#N)c[nH]4)c(C4=CCC(C)(C)CC4)n3)CCOCC2)CC1 -US20090029976A1,6,COc1cc(OC)c(C=O)cc1C>>COc1cc(O)c(C=O)cc1C -US20110130380A1,2,CC1(C)COCC(CO)O1.CS(=O)(=O)Cl>>CC1(C)COCC(COS(C)(=O)=O)O1 -US20080070948A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCc1c[nH]c2ccccc12>>Cc1ccc(S(=O)(=O)OCCCc2c[nH]c3ccccc23)cc1 -US20110015234A1,2,N#Cc1ccc(Cn2nc(C(=O)O)c3cc(F)ccc32)cc1.NCc1ccc(-c2nnn[nH]2)cc1>>N#Cc1ccc(Cn2nc(C(=O)NCc3ccc(-c4nnn[nH]4)cc3)c3cc(F)ccc32)cc1 -US20080275062A1,3,C=CCNc1cc(Cl)ncn1.COc1cccc(CNC(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c1>>C=CCNc1cc(-c2ccc(C(=O)NCc3cccc(OC)c3)cc2)ncn1 -US07507758B2,9,BrC(Br)(Br)Br.CC(C)(C)OC(=O)n1cc(C=O)c2ccccc21>>CC(C)(C)OC(=O)n1cc(C=C(Br)Br)c2ccccc21 -US20110052534A1,10,CCCOc1ccc(-c2ccc(CC(=O)OC)cn2)c(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>CCCOc1ccc(-c2ccc(C(Br)C(=O)OC)cn2)c(C(F)(F)F)c1 -US20080255183A1,7,COC(=O)[C@H](Cc1ccc(C#CCC(C)O)s1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(CCCC(C)O)s1)NC(=O)OC(C)(C)C -US08119627B2,1,NCc1ccccc1Oc1ccc(Cl)cc1.O=C1CCN(C(=O)C2CCCC2)CC1>>O=C(C1CCCC1)N1CCC(NCc2ccccc2Oc2ccc(Cl)cc2)CC1 -US20150175567A1,6,COC(=O)COc1cccc(OC2CCc3ccc(-c4cccc(F)c4)cc32)c1>>O=C(O)COc1cccc(OC2CCc3ccc(-c4cccc(F)c4)cc32)c1 -US20090286985A1,3,Brc1c2ccccc2cc2ccccc12.OB(O)c1ccccc1>>c1ccc(-c2c3ccccc3cc3ccccc23)cc1 -US20060014805A1,1,CCOC(=O)C(C)Br.Sc1nc2cc(Cl)ccc2s1>>CCOC(=O)C(C)Sc1nc2cc(Cl)ccc2s1 -US20050182113A1,2,CCC(=O)OC(=O)CC.Cc1onc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1>>CCC(=O)NS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1 -US20090124598A1,2,CNCc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1.O=C(Cl)N1CCCCC1>>CN(Cc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1)C(=O)N1CCCCC1 -US20070161681A1,2,CC(Oc1ccc(CN)c(F)c1)C(=O)OC(C)(C)C.O=C(O)c1cccnc1Oc1ccc(F)cc1>>CC(Oc1ccc(CNC(=O)c2cccnc2Oc2ccc(F)cc2)c(F)c1)C(=O)OC(C)(C)C -US06693123B2,6,COC(=O)[C@@H](N)CC(C)(C)C(=O)c1cccc(NCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1-c1cccc2ccccc12>>CC(C)(C[C@H](N)C(=O)O)C(=O)c1cccc(NCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1-c1cccc2ccccc12 -US08057985B2,1,C=C(C)C(=O)[O-].O=C(CCCCl)OC(C(F)(F)F)C(F)(F)S(=O)(=O)[O-]>>C=C(C)C(=O)OCCCC(=O)OC(C(F)(F)F)C(F)(F)S(=O)(=O)[O-] -US06294557B1,9,ClC(Cl)(Cl)Cl.O[C@@H]1CCN(Cc2ccccc2)C1>>Cl[C@H]1CCN(Cc2ccccc2)C1 -US20150166569A1,3,C#CC(C)(O)CO.CNC(=O)c1c(C(N)=O)nc2n1CCOc1ccc(Br)cc1-2>>CNC(=O)c1c(C(N)=O)nc2n1CCOc1ccc(C#CC(C)(O)CO)cc1-2 -US20120232096A1,1,CCOc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)C2.COc1ccc(Br)cc1C>>CCOc1c(C)c(N2CCN(c3ccc(OC)c(C)c3)CC2)c(C)c2c1OC(C)C2 -US20150175560A1,1,OCC1CCO1.Oc1noc2ccc(Br)cc12>>Brc1ccc2onc(OCC3CCO3)c2c1 -US20050107449A1,7,CCOC(=O)C(C)c1oc(-c2ccc(C(F)(F)F)cc2)nc1C(C)C>>CC(C)c1nc(-c2ccc(C(F)(F)F)cc2)oc1C(C)CO -US07595327B2,2,CC(C)(C)ON.COC(=O)[C@@]1(C)CN(C(=O)OC(C)(C)C)CC[C@H]1NS(=O)(=O)c1ccc(OCc2ccccc2)cc1>>CC(C)(C)ONC(=O)[C@@]1(C)CN(C(=O)OC(C)(C)C)CC[C@H]1NS(=O)(=O)c1ccc(OCc2ccccc2)cc1 -US05869493,9,CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CCOC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)Cn1cnc2c(Cl)nc(N)nc21>>CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CCOC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)Cn1cnc2cnc(N)nc21 -US06365602B1,2,CCNC[C@@H](CCN1CCC(c2ccccc2[S@](C)=O)CC1)c1ccc(Cl)c(Cl)c1.N#Cc1cc(C(=O)O)c2ccccc2c1>>CCN(C[C@@H](CCN1CCC(c2ccccc2[S@](C)=O)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(C#N)cc2ccccc12 -US07632840B2,2,COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1(C(N)=O)CCNCC1.CS(=O)(=O)Cl>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1(C(N)=O)CCN(S(C)(=O)=O)CC1 -US07781426B2,3,CN(C)C=O.Cc1cc(F)ccc1C(F)(F)F>>Cc1cc(F)c(C=O)cc1C(F)(F)F -US05204473,1,CCCCN.CON1C(C)(C)CC(=O)CC1(C)C>>CCCCNC1CC(C)(C)N(OC)C(C)(C)C1 -US04753951,7,CNc1c([N+](=O)[O-])cnc2ccccc12>>CNc1c(N)cnc2ccccc12 -US20100179168A1,3,COc1ccc([N+](=O)[O-])cc1NS(=O)(=O)c1ccc(Br)c(F)c1.Cc1ccc(B(O)O)o1>>COc1ccc([N+](=O)[O-])cc1NS(=O)(=O)c1ccc(-c2ccc(C)o2)c(F)c1 -US20090286790A1,1,CCC1CC(=O)CCN1C(=O)OC(C)(C)C.NC1CCCCC1>>CCC1CC(NC2CCCCC2)CCN1C(=O)OC(C)(C)C -US08288406B2,3,CCOC(C)OC(Cc1ccccc1)C1CCC(=O)CC1.CNC.[C-]#N>>CCOC(C)OC(Cc1ccccc1)C1CCC(C#N)(N(C)C)CC1 -US20100075961A1,6,COC(=O)C(c1ccccc1)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1>>O=C(O)C(c1ccccc1)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 -US20020107252A1,2,C[Si](C)(C)N=C=O.NC(=O)c1sc(-c2cccc(Cl)c2)cc1N>>NC(=O)Nc1cc(-c2cccc(Cl)c2)sc1C(N)=O -US08815919B2,1,CNCCCC(=O)OC(C)(C)C.N#Cc1ccc(CBr)cc1>>CN(CCCC(=O)OC(C)(C)C)Cc1ccc(C#N)cc1 -US20140038989A1,2,CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)O)c3N2)cc1.Cc1ccc(CN)nc1>>CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)NCc4ccc(C)cn4)c3N2)cc1 -US20100227859A1,2,CC(C)(C)c1nc(-c2ccc3c(c2)oc2ccc(S(=O)(=O)Cl)cc23)no1.COC(=O)CN>>COC(=O)CNS(=O)(=O)c1ccc2oc3cc(-c4noc(C(C)(C)C)n4)ccc3c2c1 -US20100261772A1,1,CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(F)cc2)CC(C)(C)C1.CCOC(=O)CCCBr>>CCOC(=O)CCCOc1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(F)cc2)cc1 -US20140242606A1,2,CC(C)(C)OC(=O)NCCN.O=C(O)C=Cc1cc2ccc(O)cc2oc1=O>>CC(C)(C)OC(=O)NCCNC(=O)C=Cc1cc2ccc(O)cc2oc1=O -US05942546,2,Cc1ccc(S(N)(=O)=O)cc1.S=C=Nc1ccc(Cl)cc1>>Cc1ccc(S(=O)(=O)NC(=S)Nc2ccc(Cl)cc2)cc1 -US20040106645A1,1,COc1ccc2oc(=O)cc(NC3CCNCC3)c2c1.O=Cc1cccc(OC(F)(F)F)c1>>COc1ccc2oc(=O)cc(NC3CCN(Cc4cccc(OC(F)(F)F)c4)CC3)c2c1 -US06608070B1,6,COC(=O)Cc1c(C(=O)c2ccc(Cl)cc2)[nH]c2cc(Cl)ccc12>>O=C(O)Cc1c(C(=O)c2ccc(Cl)cc2)[nH]c2cc(Cl)ccc12 -US03959296,1,CCN(CC)CCN.COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccc(Cl)c([N+](=O)[O-])c1>>CCN(CC)CCNc1ccc(C2C(C(=O)OC)=C(C)NC(C)=C2C(=O)OC)cc1[N+](=O)[O-] -US20100022583A1,7,C=C(C)CC(C(=O)OC)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2ccc(C(F)(F)F)cc2)c1>>COC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2ccc(C(F)(F)F)cc2)c1 -US20020042517A1,1,CCNC(=O)c1cc(Cl)ccn1.Nc1ccc(O)cc1>>CCNC(=O)c1cc(Oc2ccc(N)cc2)ccn1 -US20150087845A1,3,COc1c(Br)cccc1NN=C1C(=O)N(c2ccc(C)c(C)c2)N=C1C.O=C(O)c1cccc(B(O)O)c1>>COc1c(NN=C2C(=O)N(c3ccc(C)c(C)c3)N=C2C)cccc1-c1cccc(C(=O)O)c1 -US20140031336A1,6,COC(=O)c1ccc(-c2ccc3c(c2)[C@H](NC(=O)OC(C)(C)C)C[C@H](C)N3C(C)=O)nc1>>CC(=O)N1c2ccc(-c3ccc(C(=O)O)cn3)cc2[C@H](NC(=O)OC(C)(C)C)C[C@@H]1C -US08524751B2,3,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.Cc1ccc(S(=O)(=O)n2ncc3c(C#N)cc(Br)cc32)cc1>>Cc1ccc(S(=O)(=O)n2ncc3c(C#N)cc(-c4cccc5[nH]ccc45)cc32)cc1 -US20100216746A1,2,COC(=O)c1cc2ccc(OC)cc2[nH]1.N#Cc1cc(Cl)cc(Oc2cc(CN)ccc2Cl)c1>>COc1ccc2cc(C(=O)NCc3ccc(Cl)c(Oc4cc(Cl)cc(C#N)c4)c3)[nH]c2c1 -US06057319,7,CC1(C)OC(=O)C(c2cccc(F)c2)=C1c1ccc(S(C)(=O)=O)cc1>>CC1(C)OC(O)C(c2cccc(F)c2)=C1c1ccc(S(C)(=O)=O)cc1 -US07268150B2,2,CC(C)(C)OC(=O)NC1CCNCC1.O=C(O)CO>>CC(C)(C)OC(=O)NC1CCN(C(=O)CO)CC1 -US04581355,1,BrCCc1ccccc1.O=C(NC1CCNCC1)c1c[nH]c2ccc(F)cc12>>O=C(NC1CCN(CCc2ccccc2)CC1)c1c[nH]c2ccc(F)cc12 -US08258134B2,2,CC(C)(O)Cn1ccc(N)n1.O=C(O)C(CC1CCOCC1)n1ncc(Oc2ccccc2Cl)cc1=O>>CC(C)(O)Cn1ccc(NC(=O)C(CC2CCOCC2)n2ncc(Oc3ccccc3Cl)cc2=O)n1 -US06211234B1,1,N#Cc1ccc(O)cc1F.OCc1cccnc1>>N#Cc1ccc(OCc2cccnc2)cc1F -US20150166480A1,2,CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)O)c(F)c3)cc2)CC1.CNC>>CN(C)C(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)F)CC3)cc2)cc1F -US20070010511A1,1,CC(=O)c1cc(C)ccc1O.CCO>>CCOc1ccc(C)cc1C(C)=O -US05109013,1,CN1CC(CCCl)N(C)c2nc3ccccc3n2C1=O.CN1CCNCC1>>CN1CCN(CCC2CN(C)C(=O)n3c(nc4ccccc43)N2C)CC1 -US20140094462A1,2,NCc1ccc(Cl)cc1.O=C(O)C[C@@H]1CC=CCCC(=O)N[C@H](Cc2ccccc2)COC1=O>>O=C(C[C@@H]1CC=CCCC(=O)N[C@H](Cc2ccccc2)COC1=O)NCc1ccc(Cl)cc1 -US07425568B2,6,COc1ccc2c(=O)c(-c3cccc(F)c3)coc2c1>>O=c1c(-c2cccc(F)c2)coc2cc(O)ccc12 -US05013829,3,FC(F)(F)[Zn+].Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>Nc1nc(C(F)(F)F)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O -US20090291938A1,1,CN1C(=O)C(CC#N)CN(C2CCCC2)c2nc(Cl)ncc21.COc1cc(C(=O)O)ccc1N>>COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(CC#N)C(=O)N2C -US07230020B2,2,NCCc1cccs1.O=C(O)c1cc(Cl)ccc1Cl>>O=C(NCCc1cccs1)c1cc(Cl)ccc1Cl -US20100160335A1,1,CI.Oc1cccc2cccnc12>>COc1cccc2cccnc12 -US08946237B2,3,CCc1sc(C(=O)N[C@@H]2[C@H](NC(=O)OC(C)(C)C)CCCC2(F)F)cc1B1OC(C)(C)C(C)(C)O1.FC(F)Oc1cnc2c(Br)cnn2c1>>CCc1sc(C(=O)N[C@@H]2[C@H](NC(=O)OC(C)(C)C)CCCC2(F)F)cc1-c1cnn2cc(OC(F)F)cnc12 -US20150239827A1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C[C@@H]1Cc2ccccc2C2(C1)OCCO2>>CCOC(=O)C=C[C@@H]1Cc2ccccc2C2(C1)OCCO2 -US20090286790A1,1,CCC1CC(N)CC(Cc2ccccc2)N1C(=O)OC(C)(C)C.Clc1ncc(Br)cn1>>CCC1CC(Nc2ncc(Br)cn2)CC(Cc2ccccc2)N1C(=O)OC(C)(C)C -US20110237573A1,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Clc1cccnn1>>Nc1ccc(-c2cccnn2)cn1 -US20090306041A1,6,COc1ccc(CN2CCc3cc(C(C)(C)C=O)ccc3C2=O)cc1>>CC(C)(C=O)c1ccc2c(c1)CCNC2=O -US05990116,1,COc1ccc(OC)c(CBr)c1.NC(=O)c1cc(O)ccc1NC=O>>COc1ccc(OC)c(COc2ccc(NC=O)c(C(N)=O)c2)c1 -US08501780B2,3,CC(=O)Nc1cccc(B(O)O)c1.CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(Br)cc23)CC1>>CC(=O)Nc1cccc(-c2cc(C(N)=O)c3[nH]nc(C4CCN(C(=O)OC(C)(C)C)CC4)c3c2)c1 -US06794510B2,2,C=C(C(=O)O)[C@@H](O)c1ccccc1.CCOC(=O)CN>>C=C(C(=O)NCC(=O)OCC)[C@@H](O)c1ccccc1 -US20110053933A1,2,CC(C)[C@H](N)C(=O)N1CCC(Oc2ccc(C(F)(F)F)nc2)CC1.O=C(O)c1nc2ccccc2nc1O>>CC(C)[C@H](NC(=O)c1nc2ccccc2nc1O)C(=O)N1CCC(Oc2ccc(C(F)(F)F)nc2)CC1 -US20090227560A1,2,C(=C/[C@@H]1CN(Cc2ccccc2)CCN1)\C1CC1.O=C(O)c1ncn([C@H]2CCCC[C@H]2O)c1-c1ccccc1>>O=C(c1ncn([C@H]2CCCC[C@H]2O)c1-c1ccccc1)N1CCN(Cc2ccccc2)C[C@H]1/C=C/C1CC1 -US20080045530A1,1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](O)C[C@H]1C(=O)O.COc1ccc2c(Cl)cc(-c3ccccc3)nc2c1>>COc1ccc2c(O[C@@H]3C[C@H](NC(=O)OC(C)(C)C)[C@H](C(=O)O)C3)cc(-c3ccccc3)nc2c1 -US05451347,1,CCCCN(CCCC)CCCC.ClCc1ccc(CCl)cc1>>CCCC[N+](CCCC)(CCCC)Cc1ccc(CCl)cc1 -US07772238B2,9,CCOC(=O)c1cc2ccc(C(C)N=[N+]=[N-])cc2s1>>CCOC(=O)c1cc2ccc(C(C)N)cc2s1 -US20090253689A1,1,C1COCCN1.N#Cc1cc2nnc(Cl)n2cc1-c1ccc(Cl)cc1Cl>>N#Cc1cc2nnc(N3CCOCC3)n2cc1-c1ccc(Cl)cc1Cl -US05124337,3,C=O.COc1ccc(CC(N)c2ccccc2)cc1OC>>COc1cc2c(cc1OC)CC(c1ccccc1)NC2 -US20120270892A1,1,COc1cc(/C=C2\SC(=O)NC2=O)nc(N2CCC(CN)CC2)n1.O=Cc1cccc(-c2ccsc2)n1>>COc1cc(/C=C2\SC(=O)NC2=O)nc(N2CCC(CNCc3cccc(-c4ccsc4)n3)CC2)n1 -US20040235926A1,1,CI.O=C(NC1CC2CCC1C2)c1nn(-c2ccccc2Cl)c(Oc2ccc3ccccc3c2)c1CO>>COCc1c(C(=O)NC2CC3CCC2C3)nn(-c2ccccc2Cl)c1Oc1ccc2ccccc2c1 -US07378417B2,2,Nc1cccc(S(=O)(=O)N2CCC[C@H]2CO)c1.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)cc3)nc12>>O=C(Nc1cccc(S(=O)(=O)N2CCC[C@H]2CO)c1)c1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)cc3)nc12 -US07932247B2,2,CC(C)(C)OC(=O)N1CCC(Cc2cccc(C(=O)O)c2)CC1.NCc1ccc(F)c(Br)c1>>CC(C)(C)OC(=O)N1CCC(Cc2cccc(C(=O)NCc3ccc(F)c(Br)c3)c2)CC1 -US20100179185A1,1,Cc1nc(Br)ccc1F.Nc1c(C(=O)N2CC[C@@H](OC3CCCCO3)C2)sc2c1ccc(=O)n2-c1c(F)cccc1F>>Cc1nc(Nc2c(C(=O)N3CC[C@@H](OC4CCCCO4)C3)sc3c2ccc(=O)n3-c2c(F)cccc2F)ccc1F -US05554620,7,CC(C)Oc1cccc(C=O)c1>>CC(C)Oc1cccc(CO)c1 -US08357707B2,9,COC(=O)[C@@H]1[C@H](CN=[N+]=[N-])CCN1[C@@H](C)c1ccccc1.[NH4+]>>C[C@@H](c1ccccc1)N1CC[C@@H](CN=[N+]=[N-])[C@H]1C(N)=O -US06326359B1,2,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CCN)nc32)[C@H](O)[C@@H]1O.O=S(=O)(Cl)c1ccccc1>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CCNS(=O)(=O)c4ccccc4)nc32)[C@H](O)[C@@H]1O -US04587331,1,NN.O=C[C@@H](O)[C@H](O)[C@H](O)CO>>NN=C[C@@H](O)[C@H](O)[C@H](O)CO -US20090048258A1,3,O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(Cl)cc(-c2ccccc2)n1.OB(O)c1cccc(OC(F)(F)F)c1>>O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(-c2cccc(OC(F)(F)F)c2)cc(-c2ccccc2)n1 -US04699905,1,CC(C)(C)OC(=O)CN1CC(c2ccccc2)SCC(N)C1=O.CCOC(=O)C(Br)CCc1ccccc1>>CCOC(=O)C(CCc1ccccc1)NC1CSC(c2ccccc2)CN(CC(=O)OC(C)(C)C)C1=O -US08440651B2,2,CC(C)C(=O)O.NCc1ccc2nc(Cl)nc(N3CCOCC3)c2n1>>CC(C)C(=O)NCc1ccc2nc(Cl)nc(N3CCOCC3)c2n1 -USRE043728E1,8,OCCCOc1ccc(CO)cc1>>O=Cc1ccc(OCCCO)cc1 -US07271266B2,2,N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCCN.O=C(Cl)c1ccccc1>>N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCCNC(=O)c1ccccc1 -US20090221642A1,2,CC1(N2CCC(n3c(=O)[nH]c4cc(F)c(F)cc43)CC2)CCNC1.CCOC(=O)Cl>>CCOC(=O)N1CCC(C)(N2CCC(n3c(=O)[nH]c4cc(F)c(F)cc43)CC2)C1 -US08044069B2,1,CC(C)(C)OC(=O)N[C@H]1CCNC1.O=Cc1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N[C@H]1CCN(Cc2cccc(C(F)(F)F)c2)C1 -US20140005188A1,7,COC(=O)C1CC(F)CN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CC(F)CC(CO)C1 -US06056895,7,CCC=C1CCC(CC(=O)OC)CC1>>CCC=C1CCC(CCO)CC1 -US20120101136A1,1,CC(C)Oc1ccc(-c2nc(-c3ccc(O)cc3F)no2)cc1C#N.CCOC(=O)CCCBr>>CCOC(=O)CCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c(F)c1 -US20110212940A1,3,Brc1ccc2occc2c1.[Zn+]C1CCCCC1>>c1cc2cc(C3CCCCC3)ccc2o1 -US20130150364A1,1,FC(F)c1nc2ccccc2n1-c1cc(Cl)nc(N2CCOCC2)n1.NS(=O)(=O)c1ccc(CN2CCOCC2)cc1>>O=S(=O)(Nc1cc(-n2c(C(F)F)nc3ccccc32)nc(N2CCOCC2)n1)c1ccc(CN2CCOCC2)cc1 -US20100249123A1,2,CC(C)(CC#N)c1ccc(N)cc1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CC#N)cc2)cc1OC -US20110257151A1,6,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(C(=O)NCCN(C)C)c1)N2>>CN(C)CCNC(=O)c1cccc(C2Nc3ccc(C(=O)O)cc3CC2(C)C)c1 -US20060160832A1,7,COc1cc2nccc(Oc3ccc([N+](=O)[O-])cn3)c2cc1OC>>COc1cc2nccc(Oc3ccc(N)cn3)c2cc1OC -US06667404B2,4,CC(C)C(N)=S.CCOC(=O)C(=O)CBr>>CCOC(=O)c1csc(C(C)C)n1 -US04812565,1,C1COCCN1.CN1CC(CCCl)Oc2ncccc2C1=O>>CN1CC(CCN2CCOCC2)Oc2ncccc2C1=O -US20070010670A1,1,CCOC(=O)CBr.O=C(c1cc(Cl)c(O)c(Cl)c1)N1CCOc2ccccc21>>CCOC(=O)COc1c(Cl)cc(C(=O)N2CCOc3ccccc32)cc1Cl -US07456168B2,7,CC1CN(c2ccc([N+](=O)[O-])nc2)CC(C)O1>>CC1CN(c2ccc(N)nc2)CC(C)O1 -US20090253677A1,2,CCOC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CC1CCC2(OCC(=O)O)CC1.CNC>>CCOC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CC1CCC2(OCC(=O)N(C)C)CC1 -US20020082260A1,2,CS(=O)(=O)c1cccc2c1CN([C@@H](CC1CCCCC1)C(=O)O)C2=O.Nc1nccs1>>CS(=O)(=O)c1cccc2c1CN([C@@H](CC1CCCCC1)C(=O)Nc1nccs1)C2=O -US20110144128A1,1,Cc1cc(Br)ccc1S(=O)(=O)N(C)C.Cc1cc(C(N)=O)c(C)n1-c1ccccc1C(F)(F)F>>Cc1cc(NC(=O)c2cc(C)n(-c3ccccc3C(F)(F)F)c2C)ccc1S(=O)(=O)N(C)C -US20090197897A1,2,Cc1c[nH]cc1C(=O)O.Fc1ccc(-c2noc([C@H]3CCCNC3)n2)cc1>>Cc1c[nH]cc1C(=O)N1CCC[C@H](c2nc(-c3ccc(F)cc3)no2)C1 -US06900200B2,2,COc1cc(-c2ccccc2F)c(Cl)cc1C(=O)O.c1ccc2c(c1)Cn1cccc1CN2>>COc1cc(-c2ccccc2F)c(Cl)cc1C(=O)N1Cc2cccn2Cc2ccccc21 -US20110269960A1,2,CCn1c(Oc2cccc(N3CCN(C(C)=O)CC3)c2)nnc1[C@@H](C)N.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1>>CCn1c(Oc2cccc(N3CCN(C(C)=O)CC3)c2)nnc1[C@@H](C)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 -US06265411B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cc[nH]c1>>CC(C)(C)OC(=O)n1cccc1 -US20100041892A1,7,CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC)cc1OCC1CCCO1>>CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCCOC)cc1OCC1CCCO1 -US20090163525A1,6,Cc1ccc(NC(=O)OC(C)(C)C)cc1Nc1ccc2ncn(C)c(=O)c2c1>>Cc1ccc(N)cc1Nc1ccc2ncn(C)c(=O)c2c1 -US06140351,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1scc(CCN)c1Cl>>COC(=O)c1scc(CCNC(=O)OC(C)(C)C)c1Cl -US06194440B1,2,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O.OCCCc1cccnc1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)OCCCc1cccnc1 -US07902195B2,3,CCCOCCn1c(=O)c(N2CCN(CCO)CC2)nc2cnc(Cl)cc21.COc1ccc(B(O)O)cn1>>CCCOCCn1c(=O)c(N2CCN(CCO)CC2)nc2cnc(-c3ccc(OC)nc3)cc21 -US06559149B1,2,CCOC(=O)c1cc(C)c(N)c(C)c1.O=C(Cl)OCc1ccccc1>>CCOC(=O)c1cc(C)c(NC(=O)OCc2ccccc2)c(C)c1 -US06605626B2,1,COc1ccc(C(=O)Nc2ccccc2NC(=O)C2CCNCC2)cc1.O=Cc1ccc([N+](=O)[O-])cc1>>COc1ccc(C(=O)Nc2ccccc2NC(=O)C2CCN(Cc3ccc([N+](=O)[O-])cc3)CC2)cc1 -US06881736B1,4,CC(C)=O.Nc1ncccc1C=O>>Cc1ccc2cccnc2n1 -US20090203750A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC[C@@H]1C[C@H]1c1ccccc1Br>>CC(C)(C)OC(=O)NC[C@@H]1C[C@H]1c1ccccc1Br -US20020111340A1,1,C1COCCN1.C[C@@H]1CC[C@@H](C)N1C(=O)c1ccc(-c2ccc(OCCCCl)cc2)cc1>>C[C@@H]1CC[C@@H](C)N1C(=O)c1ccc(-c2ccc(OCCCN3CCOCC3)cc2)cc1 -US20020032184A1,3,CC(=O)CC(C)=O.O=Cc1cc(Cl)cc(Cl)c1>>CC(=O)C(=Cc1cc(Cl)cc(Cl)c1)C(C)=O -US06420561B1,1,BrCc1ccccc1.N[C@H](CO)Cc1ccccc1>>N[C@H](COCc1ccccc1)Cc1ccccc1 -US20110028467A1,3,Brc1cnc2c(c1)NCCO2.CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C>>c1cc(-c2cnc3c(c2)NCCO3)c2cc[nH]c2c1 -US20100081692A1,7,COC(=O)c1ccc(C(F)(F)F)cc1O>>OCc1ccc(C(F)(F)F)cc1O -US20130303508A1,1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc([N+](=O)[O-])cc2)C1 -US05260278,9,CC(C)(C)OC(=O)N(CC(=O)O)C1CCCCC1>>CC(C)(C)OC(=O)N(CC=O)C1CCCCC1 -US20150112058A1,1,O=Cc1cc(Cl)ccc1F.c1nc[nH]n1>>O=Cc1cc(Cl)ccc1-n1cncn1 -US20090054398A1,2,CC(C)C[C@H](N)C(=O)N[C@@H]1C(=O)Nc2ccccc2O[C@@H]1c1ccccc1.O=C(O)Cc1cc(F)cc(F)c1>>CC(C)C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H]1C(=O)Nc2ccccc2O[C@@H]1c1ccccc1 -US20030187020A1,1,N#Cc1ccc(F)c(Br)c1.OCc1ccccc1>>N#Cc1ccc(OCc2ccccc2)c(Br)c1 -US09133168B2,7,FC(F)(F)Oc1cccc2[nH]ccc12>>FC(F)(F)Oc1cccc2c1CCN2 -US20090197884A1,6,O=C(CNC(=O)c1cccc(C(F)(F)F)c1)N[C@@H]1CCN(C2CCN(C(=O)OCc3ccccc3)CC2)C1>>O=C(CNC(=O)c1cccc(C(F)(F)F)c1)N[C@@H]1CCN(C2CCNCC2)C1 -US20080051405A1,7,CN1CCC(COc2cccc(C#N)c2)CC1>>CN1CCC(COc2cccc(CN)c2)CC1 -US20080248589A1,6,CC(=O)SCCCCCCCCCCCOCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCOCCCCCCCCCCCS -US05965589,3,CCOC(=O)CP(=O)(OCC)OCC.COc1cc(C=O)ccc1OCc1coc(-c2ccccc2)n1>>CCOC(=O)C=Cc1ccc(OCc2coc(-c3ccccc3)n2)c(OC)c1 -US07498325B2,2,CC(C)(C)OC(=O)N[C@H](Cc1cc(Br)c(N)c(Br)c1)C(=O)O.c1cc(N2CCNCC2)ncn1>>CC(C)(C)OC(=O)N[C@H](Cc1cc(Br)c(N)c(Br)c1)C(=O)N1CCN(c2ccncn2)CC1 -US20090042945A1,6,CCOC(=O)c1cccc(-c2ccc3onc(NCC(C)(C)C)c3c2)c1>>CC(C)(C)CNc1noc2ccc(-c3cccc(C(=O)O)c3)cc12 -US07157454B2,1,C1CNC1.O=Cc1ccc(CC(NC(=O)CC(NS(=O)(=O)c2ccc3ccccc3c2)c2ccccc2)C(=O)N2CCCC2)cc1>>O=C(CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NC(Cc1ccc(CN2CCC2)cc1)C(=O)N1CCCC1 -US20150259323A1,6,CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)NCc3cc(C)cc(C(=O)OC)c3)cn2)C1>>CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)NCc3cc(C)cc(C(=O)O)c3)cn2)C1 -US08513424B2,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.N#Cc1ccc(-n2cc(Cl)c(O)cc2=O)cc1F>>CC(C)(C)OC(=O)N1CCC(Oc2cc(=O)n(-c3ccc(C#N)c(F)c3)cc2Cl)CC1 -US20060205718A1,1,CC(C)CBr.CCOc1cc(O)cc(CO)c1>>CCOc1cc(CO)cc(OCC(C)C)c1 -US20070010537A1,2,COc1cccc2c1CCCCN2.O=[N+]([O-])c1cc(S(=O)(=O)Cl)ccc1Cl>>COc1cccc2c1CCCCN2S(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1 -US07608629B2,1,C[C@H]1C[C@@H](O)CCN1C(=O)OC(C)(C)C.Fc1cccc(Br)c1>>C[C@H]1C[C@@H](Oc2cccc(Br)c2)CCN1C(=O)OC(C)(C)C -US20080255083A1,1,CC1(O)CCNCC1.O=C(Cn1ccc(OCc2ccccc2)cc1=O)c1ccc(CBr)c(F)c1>>CC1(O)CCN(Cc2ccc(C(=O)Cn3ccc(OCc4ccccc4)cc3=O)cc2F)CC1 -US07834051B2,1,CC1NC(=O)C(C)(C)C1=O.Cc1c(Br)ccc(C#N)c1F>>Cc1c(N2C(=O)C(C)(C)C(=O)C2C)ccc(C#N)c1F -US20130280245A1,7,COc1ccccc1-c1nnc2ccc(-c3ccc(OC)c([N+](=O)[O-])c3)cn12>>COc1ccc(-c2ccc3nnc(-c4ccccc4OC)n3c2)cc1N -US04329465,7,C=C1c2ccccc2CC(=O)Cc2ccccc21>>CC1c2ccccc2CC(=O)Cc2ccccc21 -US20030054510A1,2,CC(C)O.CCOC(Cc1ccc(OCc2ccccc2)cc1)C(=O)O>>CCOC(Cc1ccc(OCc2ccccc2)cc1)C(=O)OC(C)C -US20080004348A1,2,CCN=C=O.COc1ccc2cccc(C(CN)CO)c2c1>>CCNC(=O)NCC(CO)c1cccc2ccc(OC)cc12 -US20140010783A1,6,COC(=O)c1cccc(Nc2n[nH]c(N)n2)c1>>Nc1nc(Nc2cccc(C(=O)O)c2)n[nH]1 -US20100120806A1,1,Clc1ccnc(Cl)c1.Nc1ccc(O)c(F)c1>>Nc1ccc(Oc2ccnc(Cl)c2)c(F)c1 -US20130253002A1,1,CCOP(=O)(CCCBr)OCC.Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(O)cc3C)cc12>>CCOP(=O)(CCCOc1ccc(CCc2cnc3c(N)nc4cc(C)ccc4c3c2)c(C)c1)OCC -US20100292212A1,2,CNCCc1ccccn1.O=C1N(c2ccc(OC(F)(F)F)cc2)CCC12CCN(S(=O)(=O)Cl)CC2>>CN(CCc1ccccn1)S(=O)(=O)N1CCC2(CCN(c3ccc(OC(F)(F)F)cc3)C2=O)CC1 -US20070066624A1,6,Cc1nc(Oc2ccc(C(=O)OC(C)(C)C)cc2)ccc1CN1CCC(N2C(=O)N(C3CCCC3)C[C@H]2CC(C)C)CC1>>Cc1nc(Oc2ccc(C(=O)O)cc2)ccc1CN1CCC(N2C(=O)N(C3CCCC3)C[C@H]2CC(C)C)CC1 -US20150252000A1,7,N#Cc1ccc2[nH]cc(C(=O)CCCCl)c2c1>>N#Cc1ccc2[nH]cc(CCCCCl)c2c1 -US20150141400A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)c1cc(Br)c(CBr)c(Br)c1N>>CCOC(=O)c1cc(Br)c(CN2CCN(C(=O)OC(C)(C)C)CC2)c(Br)c1N -US20090324581A1,6,CCOC(=O)CCN(CC(=O)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21)C1CC1>>O=C(O)CCN(CC(=O)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21)C1CC1 -US20100331328A1,1,C[O-].N#Cc1cnc(Nc2cc3cccc(Br)c3cn2)cn1>>COc1cccc2cc(Nc3cnc(C#N)cn3)ncc12 -US08183262B2,2,Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1.OC1CNC1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)N4CC(O)C4)c3)n2)n1 -US20130324555A1,2,N#Cc1ccc(Cl)c(N)c1.O=C(O)c1cc(Cl)ccc1O>>N#Cc1ccc(Cl)c(NC(=O)c2cc(Cl)ccc2O)c1 -US20040247523A1,9,CC(C)(C)OC(=O)NCCCNC(=O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1>>CC(C)(C)OC(=O)NCCCNC(=O)/C=C/c1nc(CSc2ccccc2Cl)ccc1OCCc1ccccc1 -US20080153850A1,3,Clc1cccc(Cl)n1.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(B(O)O)ccc1Cl>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(-c2cccc(Cl)n2)ccc1Cl -US05010083,1,CN.COc1ccc2c(c1)C(CC=O)CC(=O)N2C>>CNCCC1CC(=O)N(C)c2ccc(OC)cc21 -US20130237571A1,6,CCOC(=O)C1CC1c1ccc(OC)cc1>>COc1ccc(C2CC2C(=O)O)cc1 -US05242912,7,CC(=O)N1CCc2cc(Br)cc([N+](=O)[O-])c21>>CC(=O)N1CCc2cc(Br)cc(N)c21 -US08518972B2,1,C1COCCN1.NC(=O)[C@@H](CCC(=O)OCc1ccccc1)N1Cc2c(OCc3ccc(CBr)cc3)cccc2C1=O>>NC(=O)C(CCC(=O)OCc1ccccc1)N1Cc2c(OCc3ccc(CN4CCOCC4)cc3)cccc2C1=O -US05849735,2,O=C(Cl)c1ccc(NC(=O)c2ccccc2-c2ccccc2)nc1.c1ccc2c(c1)CNc1ccccc1N2>>O=C(Nc1ccc(C(=O)N2Cc3ccccc3Nc3ccccc32)cn1)c1ccccc1-c1ccccc1 -US08536214B2,7,COC(=O)c1ccc2c(c1)CCC2NS(=O)(=O)C(C)C>>CC(C)S(=O)(=O)NC1CCc2cc(CO)ccc21 -US20090099178A1,3,N#Cc1ccc2c(c1)c(Br)nn2C1CCCCO1.OB(O)c1ccc2cc(OCCN3CCCCC3)ccc2c1>>N#Cc1ccc2c(c1)c(-c1ccc3cc(OCCN4CCCCC4)ccc3c1)nn2C1CCCCO1 -US20080027112A1,1,CCOC(=O)CN.COc1ccc2c(Cl)cc(=O)oc2c1OC1CCCC1>>CCOC(=O)CNc1cc(=O)oc2c(OC3CCCC3)c(OC)ccc12 -US20120295897A1,1,Fc1cccnc1CCl.O=C1Nc2ccccc2[C@]12COc1cc3c(cc12)OCCO3>>O=C1N(Cc2ncccc2F)c2ccccc2[C@]12COc1cc3c(cc12)OCCO3 -US06358971B1,3,CON(C)C(=O)c1ccc(Cl)nc1.Fc1cccc(Br)c1F>>O=C(c1ccc(Cl)nc1)c1cccc(F)c1F -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)CCCO2>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)CCCO2 -US08859608B2,2,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1CO.O=C(O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1COC(=O)c1ccc([N+](=O)[O-])cc1 -US20090048258A1,3,O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(Cl)cc(-c2ccccc2)n1.OCCCc1cccc(B(O)O)c1>>O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(-c2cccc(CCCO)c2)cc(-c2ccccc2)n1 -US20090275567A1,2,CS(=O)(=O)Cl.Cc1ncc(-c2ccnc(N[C@H]3CCCNC3)n2)n1C(C)C>>Cc1ncc(-c2ccnc(N[C@H]3CCCN(S(C)(=O)=O)C3)n2)n1C(C)C -US20080188528A1,6,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)c1cccn(Cc2ccccc2C(F)(F)F)c1=O)C(=O)O>>NCCC[C@H](NC(=O)c1cccn(Cc2ccccc2C(F)(F)F)c1=O)C(=O)O -US07786114B2,1,COc1cc2c(nc1OC)c(-c1cc3c(CCl)ccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2C.Oc1ccccc1>>COc1cc2c(nc1OC)c(-c1cc3c(COc4ccccc4)ccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2C -US20090130090A1,2,CN.COc1ccc(Cl)cc1CC(=O)Cl>>CNC(=O)Cc1cc(Cl)ccc1OC -US20150094474A1,1,CC1(C)C(C=O)C1/C=C(\Cl)C(F)(F)F.N#CC(N)c1cccc(Oc2ccccc2)c1>>CC1(C)C(/C=C(\Cl)C(F)(F)F)C1CNC(C#N)c1cccc(Oc2ccccc2)c1 -US20100160386A1,6,COC(=O)c1cnc(-c2ccc(C)c(F)c2)cc1Oc1ccccc1Cl>>Cc1ccc(-c2cc(Oc3ccccc3Cl)c(C(=O)O)cn2)cc1F -US20090039317A1,3,Brc1ccc(I)cc1.OB(O)c1cc2ccccc2c2ccccc12>>Brc1ccc(-c2cc3ccccc3c3ccccc23)cc1 -US20140213549A9,6,COc1ccc(COC2CC(C)(C)Cc3nc(C4CCN(c5ncc(OC6CCN(C)CC6)cn5)CC4)c(C(F)c4ccc(C(F)(F)F)cc4)c(C4CCC(F)(F)CC4)c32)cc1>>CN1CCC(Oc2cnc(N3CCC(c4nc5c(c(C6CCC(F)(F)CC6)c4C(F)c4ccc(C(F)(F)F)cc4)C(O)CC(C)(C)C5)CC3)nc2)CC1 -US07271191B2,2,CCn1nc(COc2ccc(F)cc2)cc1-c1cccc(C(C)(C)N)c1.O=S(=O)(Cl)NC1CCC1>>CCn1nc(COc2ccc(F)cc2)cc1-c1cccc(C(C)(C)NS(=O)(=O)NC2CCC2)c1 -US20090048269A1,1,COc1cc(N)cc(OC)c1OC.Cc1cccc(-c2ncccc2Oc2ccnc(Cl)c2)n1>>COc1cc(Nc2cc(Oc3cccnc3-c3cccc(C)n3)ccn2)cc(OC)c1OC -US20080200475A1,2,CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(N)nc2s1.O=C(O)c1cccnc1>>CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(NC(=O)c3cccnc3)nc2s1 -US20090099106A1,6,CC(=O)Nc1ccc(Nc2cc(C)nc(N)n2)cn1>>Cc1cc(Nc2ccc(N)nc2)nc(N)n1 -US20100120810A1,2,CC(=O)Cl.COc1cc2cc(-c3cccc(N)c3)nc(C)c2cc1OC>>COc1cc2cc(-c3cccc(NC(C)=O)c3)nc(C)c2cc1OC -US04528282,9,COC(=O)C(CCC(=O)c1cccs1)(N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C)C(=O)OC>>COC(=O)C(CCC(=O)c1cccs1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C -US20070155805A1,2,CNOC.Cc1c(C(=O)O)oc2cc(C(F)(F)F)ccc12>>CON(C)C(=O)c1oc2cc(C(F)(F)F)ccc2c1C -US20040209921A1,7,COC(=O)c1cc(C#N)ccc1CN(Cc1ncccc1C)Cc1ncccc1Cl>>Cc1cccnc1CN(Cc1ccc(C#N)cc1CO)Cc1ncccc1Cl -US08592467B2,1,C[C@@H]1CCCN1[C@@H]1C[C@@H](c2nc3ccc(Br)cc3s2)C1.Cc1ccc(=O)[nH]n1>>Cc1ccc(=O)n(-c2ccc3nc([C@@H]4C[C@@H](N5CCC[C@@H]5C)C4)sc3c2)n1 -US20050136444A1,1,N#CCCCCOc1ccc(C=O)cc1Cl.N=C(N)NN>>N#CCCCCOc1ccc(C=NNC(=N)N)cc1Cl -US20140323470A1,6,O=C(CO[C@@H]1CC[C@H](N2C(=O)c3ccccc3C2=O)c2ccccc21)N1CCOCC1>>N[C@H]1CC[C@@H](OCC(=O)N2CCOCC2)c2ccccc21 -US04880819,2,COC(=O)CN.O=C(O)CN1CCCC1=O>>COC(=O)CNC(=O)CN1CCCC1=O -US20070032508A1,1,CN(C)CC(=O)N1CCC(Oc2ccc3ncnc(Cl)c3c2)CC1.Nc1ccc(O)cc1>>CN(C)CC(=O)N1CCC(Oc2ccc3ncnc(Nc4ccc(O)cc4)c3c2)CC1 -US20130053574A1,7,CC(=O)c1ccc(F)cc1>>CC(O)c1ccc(F)cc1 -US20050182040A1,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1.N#Cc1ccc(Br)cc1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2ccc(C#N)cc2)CC1 -US05322848,2,Cc1ccc(S(=O)(=O)Cl)cc1.OC1CCN(Cc2ccccc2)C1>>Cc1ccc(S(=O)(=O)OC2CCN(Cc3ccccc3)C2)cc1 -US05041448,7,N#CCN1CCC(Nc2nc3cncnc3n2Cc2ccc(F)cc2)CC1>>NCCN1CCC(Nc2nc3cncnc3n2Cc2ccc(F)cc2)CC1 -US20150166483A1,6,COc1cc(N)cc(OC)c1Cl>>COc1cc(N)cc(O)c1Cl -US20080214612A1,6,CS(=O)(=O)c1ccc(-c2sc3cc(OCc4ccccc4)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1>>CS(=O)(=O)c1ccc(-c2sc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1 -US20150025064A1,7,O=C1CC(c2cccc(Br)c2)=Nc2ccc([N+](=O)[O-])cc2N1>>Nc1ccc2c(c1)NC(=O)CC(c1cccc(Br)c1)=N2 -US05928562,1,CCCCCCCCCc1cnc(-c2ccc(O)cc2)nc1.FC(F)(COCCCCCBr)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CCCCCCCCCc1cnc(-c2ccc(OCCCCCOCC(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc2)nc1 -US20140120087A1,6,CCOc1cc(C(=O)OC)ccc1Br>>CCOc1cc(C(=O)O)ccc1Br -US20110212956A1,2,Cc1noc(C)c1-c1ccc2c(c1)CCNC2C.O=C(O)c1cc2ncc(Br)cn2n1>>Cc1noc(C)c1-c1ccc2c(c1)CCN(C(=O)c1cc3ncc(Br)cn3n1)C2C -US04208520,1,Brc1ccncc1.Nc1nc(N)c2c(ccc3[nH]ccc32)n1>>Nc1nc(N)c2c(ccc3c2ccn3-c2ccncc2)n1 -US05739345,1,CC(C)(C)OC(=O)N1c2ccccc2CC1CO.O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1c2ccccc2CC1COc1ccc(CC2SC(=O)N(C(c3ccccc3)(c3ccccc3)c3ccccc3)C2=O)cc1 -US20140163001A1,2,C1CSCCN1.CC(C)(C)n1ncc(-c2nc(CC(=O)O)cs2)c1-c1ccc(F)cc1>>CC(C)(C)n1ncc(-c2nc(CC(=O)N3CCSCC3)cs2)c1-c1ccc(F)cc1 -US06162621,6,CCOC(=O)C1CCN1Cc1ccccc1>>O=C(O)C1CCN1Cc1ccccc1 -US05886014,1,CI.COc1ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>COc1ccc(N(C)C(=O)OC(C)(C)C)c([N+](=O)[O-])c1 -US08003649B2,1,CCS(=O)(=O)c1ccc(C=O)cc1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>CCS(=O)(=O)c1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US20100272680A1,2,CC1CC(N2CCOC2=O)CCN1.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl>>C[C@H]1C[C@@H](N2CCOC2=O)CCN1C(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl -US20100272680A1,2,CC1CC(N2CCOC2=O)CCN1.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl>>C[C@H]1C[C@H](N2CCOC2=O)CCN1C(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl -US06218385B1,1,Cc1nc(OCCCOS(C)(=O)=O)c([N+](=O)[O-])c(N2CCc3ccccc3CC2)n1.c1nc[nH]n1>>Cc1nc(OCCCn2cncn2)c([N+](=O)[O-])c(N2CCc3ccccc3CC2)n1 -US08722661B2,1,Cn1ccc2c(=O)[nH]c(Cl)nc21.c1cc(N2CCNCC2)ccn1>>Cn1ccc2c(=O)[nH]c(N3CCN(c4ccncc4)CC3)nc21 -US07229987B2,1,CN(C)CCCCl.Oc1ccc(-c2nc(CSCCOc3ccccc3)co2)cc1>>CN(C)CCCOc1ccc(-c2nc(CSCCOc3ccccc3)co2)cc1 -US20080312226A1,2,Nc1ccccn1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1ccccn1)OCC(Cl)(Cl)Cl -US07371869B2,2,COC(=O)c1csc(NC(=O)[C@@H](N)Cc2ccccc2)n1.COCCOc1ccc([C@@H](NC(=O)OC(C)(C)C)C(=O)O)cc1>>COCCOc1ccc(C(NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc2nc(C(=O)OC)cs2)cc1 -US20040082629A1,2,Nc1nc(C(F)(F)F)c(I)s1.O=C(Cl)c1c(Cl)cccc1Cl>>O=C(Nc1nc(C(F)(F)F)c(I)s1)c1c(Cl)cccc1Cl -US20050148624A1,2,O=C(O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc2c(c1)OCO2.OCc1ccncc1>>O=C(OCc1ccncc1)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc2c(c1)OCO2 -US20140005168A1,1,C1CNCCN1.Fc1cccc(-n2ncc3cnc(-c4cncc(C5COC5)c4)cc32)n1>>c1cc(N2CCNCC2)nc(-n2ncc3cnc(-c4cncc(C5COC5)c4)cc32)c1 -US04898871,1,CC(C)CCCN.O=C1c2ccccc2C(Cl)N1c1ccc2ccc(Cl)nc2n1>>CC(C)CCCNC1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1 -US20020160996A1,7,Cc1oc2c(C)c(C)c(NC(=O)c3ccc(F)cc3)c(C)c2c1-c1ccccc1>>Cc1oc2c(C)c(C)c(NCc3ccc(F)cc3)c(C)c2c1-c1ccccc1 -US20120018672A1,3,CCCCOc1ccc(C2CCC(C3CCC(=O)CC3)CC2)c(F)c1F.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCOc1ccc(C2CCC(C3CCC(=COC)CC3)CC2)c(F)c1F -US20140121238A1,3,COc1c(C)c(Br)c(OC)c2ccccc12.O=C(Cl)c1ccc(C(F)(F)F)cc1F>>COc1c(C)c(C(=O)c2ccc(C(F)(F)F)cc2F)c(OC)c2ccccc12 -US07662830B2,1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.Fc1ccc(-c2cc(Cl)nc(Cl)n2)cc1>>C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1cc(-c2ccc(F)cc2)nc(Cl)n1 -US20100004249A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)Nc2cccc(C(F)(F)F)c2)C(CO)C1>>CC(C)(C)OC(=O)N1CCN2C(=O)N(c3cccc(C(F)(F)F)c3)CC2C1 -US20150065468A1,1,COc1cc2nc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cnc2cc1O.ClCCBr>>COc1cc2nc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cnc2cc1OCCCl -US20100056499A1,6,CN(CC[C@H](c1ccccc1)c1c[nH]c2ncccc12)C(=O)OC(C)(C)C>>CNCC[C@H](c1ccccc1)c1c[nH]c2ncccc12 -US20080306082A1,1,CN1CCN(CCCN)CC1.Clc1nccc(-c2cc3cccc(Cl)c3s2)n1>>CN1CCN(CCCNc2nccc(-c3cc4cccc(Cl)c4s3)n2)CC1 -US04644079,1,CI.O=C1CC(O)C=C1CCCCCC(C(O)=S)c1ccccc1>>COC(=S)C(CCCCCC1=CC(O)CC1=O)c1ccccc1 -US20070135433A1,1,O=Cc1ccoc1.ON=C1CCc2cc(-c3nc(C4CCNCC4)[nH]c3-c3ccncc3)ccc21>>ON=C1CCc2cc(-c3nc(C4CCN(Cc5ccoc5)CC4)[nH]c3-c3ccncc3)ccc21 -US20150148332A1,6,COc1ccc(Cn2nc(N3CCCC3)nc2CCc2nc3c(C(F)(F)F)cc(Cl)c(C)n3n2)cc1>>Cc1c(Cl)cc(C(F)(F)F)c2nc(CCc3nc(N4CCCC4)n[nH]3)nn12 -US20080132481A1,1,CCN(CC)C(=O)OCCl.O=C(O)c1[nH]c2ccccc2c1Nc1ccncc1>>CCN(CC)C(=O)OCOC(=O)c1[nH]c2ccccc2c1Nc1ccncc1 -US07132449B2,2,CC(C)C[C@H](CC(=O)O)C(=O)O>>CC(C)C[C@@H]1CC(=O)OC1=O -US20050176724A1,7,Cc1ccc2c(OCCN3CCC(=Cc4cccc(C#N)c4)CC3)cccc2n1>>Cc1ccc2c(OCCN3CCC(Cc4cccc(C#N)c4)CC3)cccc2n1 -US20050059679A1,6,CCCCCN1C(CNC(=O)OC(C)(C)C)=Nc2cccc3nc4c(c1c23)Cn1c-4cc2c(c1=O)COC(=O)[C@]2(O)CC>>CCCCCN1C(CN)=Nc2cccc3nc4c(c1c23)Cn1c-4cc2c(c1=O)COC(=O)[C@]2(O)CC -US06900215B2,3,FC(F)(F)c1ccn2c(Br)cnc2n1.OB(O)c1ccc(F)c(-c2cccnc2)c1F>>Fc1ccc(-c2cnc3nc(C(F)(F)F)ccn23)c(F)c1-c1cccnc1 -US20100273744A1,1,CCOC(=O)CCCBr.O=C(Nc1ccn(Cc2ccc(O)cc2C(F)(F)F)n1)c1c(F)cccc1F>>CCOC(=O)CCCOc1ccc(Cn2ccc(NC(=O)c3c(F)cccc3F)n2)c(C(F)(F)F)c1 -US05082856,6,CCCCCCCCCCCCCCc1ccc(C(=O)OCC)[nH]1>>CCCCCCCCCCCCCCc1ccc(C(=O)O)[nH]1 -US20100016401A1,6,COC(=O)c1cccc2oc(C)cc12>>Cc1cc2c(C(=O)O)cccc2o1 -US20130225524A1,6,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4ccnc(C)c4)ccc23)c1>>Cc1cc(-c2ccc3c(Nc4cccc(C(=O)O)c4)c(C(N)=O)cnc3c2)ccn1 -US20040209886A1,1,CCOC(=O)c1cn2ncc(C#N)c(Cl)c2c1C.Nc1ccc(Oc2ccccc2)cc1>>CCOC(=O)c1cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c2c1C -US20050075383A1,9,COc1ccc(C=O)cc1OC1CCCC1.NO>>COc1ccc(C=NO)cc1OC1CCCC1 -US20030138376A1,2,NCCN1CCOCC1.O=C(O)c1ccc(Cl)cc1>>O=C(NCCN1CCOCC1)c1ccc(Cl)cc1 -US06608059B1,1,CCOC(=O)c1cc2cc(OCc3c(Cl)cccc3Cl)ccc2[nH]1.N#CCCCBr>>CCOC(=O)c1cc2cc(OCc3c(Cl)cccc3Cl)ccc2n1CCCC#N -US20120316147A1,2,CC(C)(N)c1nccs1.O=C(O)c1ccc(C2CCCO2)c(-c2cccc(Cl)c2)n1>>CC(C)(NC(=O)c1ccc(C2CCCO2)c(-c2cccc(Cl)c2)n1)c1nccs1 -US04278686,2,CC(=O)NCCSC1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)[C@H]([C@H](C)O)[C@H]2C1.CS(=O)(=O)Cl>>CC(=O)NCCSC1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)[C@H]([C@H](C)OS(C)(=O)=O)[C@H]2C1 -US20110046134A1,2,Cn1cc(-c2ccc(C(=O)O)cc2)cn1.NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1>>Cn1cc(-c2ccc(C(=O)NCC(=O)N3CCN(C(=O)c4ccccc4C(F)(F)F)CC3)cc2)cn1 -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1ccc(-c2cc(C)c(Br)c(C)c2)nn1>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(-c6ccc(C)nn6)cc5C)ccc(F)c43)ccc21 -US07521445B2,1,CC[C@@H]1CC[C@@H](NC(=O)[C@@H]2C[C@H]2COS(C)(=O)=O)CC1.FC(F)(F)c1ccc(N2CCNCC2)cc1>>CC[C@@H]1CC[C@@H](NC(=O)[C@@H]2C[C@H]2CN2CCN(c3ccc(C(F)(F)F)cc3)CC2)CC1 -US20140206684A1,3,Cc1ccccc1N1C(=O)c2c(C)cccc2CC1Cn1nc(I)c2c(N)ncnc21.OB(O)c1cc(O)cc(F)c1>>Cc1ccccc1N1C(=O)c2c(C)cccc2CC1Cn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21 -US20100152443A1,2,CCN=C=O.Cc1cc(Oc2ccc(C#N)cc2C(F)(F)F)n[nH]1>>CCNC(=O)n1nc(Oc2ccc(C#N)cc2C(F)(F)F)cc1C -US20110092511A1,1,CNC.ClCc1nnc2ccc3nc(Cl)c(-c4ccccc4)nc3n12>>CN(C)Cc1nnc2ccc3nc(Cl)c(-c4ccccc4)nc3n12 -US05741926,2,N#CCc1ccc(N)cc1.O=C(Br)CBr>>N#CCc1ccc(NC(=O)CBr)cc1 -US07153863B2,3,C#CCC(C)C.CSc1nccc(I)n1>>CSc1nccc(C#CCC(C)C)n1 -US20110212943A1,6,COC(=O)/C=C/c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1>>O=C(O)/C=C/c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1 -US08153644B2,6,COC(=O)C(C)(C)CC1CCN(c2ccc([N+](=O)[O-])cn2)CC1>>CC(C)(CC1CCN(c2ccc([N+](=O)[O-])cn2)CC1)C(=O)O -US20120302566A1,1,COC(=O)C[C@@H]1COc2cc(O)ccc21.O=c1ccccn1-c1cccc2c1CC[C@@H]2O>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3cccc4-n3ccccc3=O)ccc21 -US20110172230A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CN>>CNC1CCN(C(=O)OC(C)(C)C)CC1 -US20080171737A1,1,CNC.O=S1(=O)C(CCCBr)Oc2ccccc2N1c1ccccc1>>CN(C)CCCC1Oc2ccccc2N(c2ccccc2)S1(=O)=O -US20070225288A1,9,CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1=O.NO>>CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1=NO -US04980470,1,CC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CCN1.C[O-]>>COc1c(N2CCNC(C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US20150148332A1,6,COc1ccc(Cn2nc(CCc3cnc4ccc(Cl)cc4n3)nc2N2CCCC2)cc1>>Clc1ccc2ncc(CCc3n[nH]c(N4CCCC4)n3)nc2c1 -US07423185B2,1,CC1(C)OB(c2ccc(OCCOS(C)(=O)=O)cc2)OC1(C)C.C[C@H](N)[C@H](O)c1ccc(O)cc1>>C[C@H](NCCOc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)[C@H](O)c1ccc(O)cc1 -US07714010B2,2,CC(C)Oc1ccc(CCC(=O)Cl)cc1.CCCCN1C(=O)C(C)(C)c2cc(N)c([N+](=O)[O-])cc21>>CCCCN1C(=O)C(C)(C)c2cc(NC(=O)CCc3ccc(OC(C)C)cc3)c([N+](=O)[O-])cc21 -US08501992B2,2,O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1.O=S(=O)(c1cc(Cl)cc(Cl)c1O)N(Cc1ccc(F)cc1)Cc1ccc(CNCc2ccc(F)cc2)cc1>>O=S(=O)(c1cc(Cl)cc(Cl)c1)N(Cc1ccc(F)cc1)Cc1ccc(CN(Cc2ccc(F)cc2)S(=O)(=O)c2cc(Cl)cc(Cl)c2O)cc1 -US08129396B2,1,C=O.Nc1ccc(NC(=O)[C@H]2CCCCN2)cc1[N+](=O)[O-]>>CN1CCCC[C@@H]1C(=O)Nc1ccc(N)c([N+](=O)[O-])c1 -US20140031355A1,2,CC(=O)Cl.CC(O)C#Cc1ccccc1C=O>>CC(=O)OC(C)C#Cc1ccccc1C=O -US04663446,1,CCCCc1ccc(N)cc1.O=c1[nH]c(Br)nc2nc[nH]c12>>CCCCc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1 -US20030105132A1,3,Brc1ccc(Br)cc1.Brc1ccccn1>>Brc1ccc(-c2ccccn2)cc1 -US20100280024A1,4,Nc1ccc(F)cc1.OCC(O)CO>>Fc1ccc2ncccc2c1 -US20060211678A1,2,CC(C)(C)N=C=O.Cn1ncc2cc(Nc3ncnc4[nH]c(C5=CCNCC5)cc34)ccc21>>Cn1ncc2cc(Nc3ncnc4[nH]c(C5=CCN(C(=O)NC(C)(C)C)CC5)cc34)ccc21 -US06696465B2,2,CCOCC(=O)Cl.Cc1nc(Oc2ccccc2)c(N)c(NCCCCNC(=O)OC(C)(C)C)c1C>>CCOCC(=O)Nc1c(Oc2ccccc2)nc(C)c(C)c1NCCCCNC(=O)OC(C)(C)C -US20140200225A1,1,CCOC(=O)c1ccc(Cl)nc1Cl.Oc1ccc(OC(F)(F)F)cc1>>CCOC(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)nc1Cl -US20080319080A1,2,C#CCOc1c(OC)cc(C(=O)Cl)cc1OC.CC(C)CN>>C#CCOc1c(OC)cc(C(=O)NCC(C)C)cc1OC -US20060079548A1,3,COc1cccc(Br)n1.C[Sn](C)(C)c1cc2nccc(Cl)c2s1>>COc1cccc(-c2cc3nccc(Cl)c3s2)n1 -US20080227781A1,1,CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)C=O)cn1.CN>>CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CNC)cn1 -US06727245B2,7,COc1ccc(Nc2ncccc2[N+](=O)[O-])cc1OC1CCCC1>>COc1ccc(Nc2ncccc2N)cc1OC1CCCC1 -US20100190829A1,10,C=CCN(c1cccc(Cl)c1)C1CCCN(C(=O)OC(C)(C)C)C1.O>>CC(C)(C)OC(=O)N1CCCC(N(CCCO)c2cccc(Cl)c2)C1 -US20110294780A1,1,CN(C)CCCCl.N#Cc1ccc(Cn2ccc3cc(/C=C4\SC(=O)NC4=O)ccc32)c(C(F)(F)F)c1>>CN(C)CCCN1C(=O)S/C(=C\c2ccc3c(ccn3Cc3ccc(C#N)cc3C(F)(F)F)c2)C1=O -US20100210680A1,3,C=C(C)B1OC(C)(C)C(C)(C)O1.C[C@]12CN(Cc3ccccc3)C[C@H]1c1ccc(Br)c(Cl)c1CO2>>C=C(C)c1ccc2c(c1Cl)CO[C@@]1(C)CN(Cc3ccccc3)C[C@@H]21 -US20050113397A1,2,CCc1c(C)c(C#N)c2nc3ccccc3n2c1NCC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CCc1c(C)c(C#N)c2nc3ccccc3n2c1N1CC[C@H](NC(=O)OCc2ccccc2)C1=O -US20130172339A1,3,COc1ccc(F)cc1B(O)O.O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(Br)s1>>COc1ccc(F)cc1-c1ccc(S(=O)(=O)Nc2cccc(-c3nnn[nH]3)c2)s1 -US20050203160A1,1,CCOC(=O)Cn1ccc2ccc(O)cc21.OCc1cc(-c2ccc(C(F)(F)F)cc2)nn1CC(F)(F)F>>CCOC(=O)Cn1ccc2ccc(OCc3cc(-c4ccc(C(F)(F)F)cc4)nn3CC(F)(F)F)cc21 -US20080027050A1,2,CCOC(=O)Cc1ccc(OCc2csc3nc(C(=O)OCC)[nH]c(=O)c23)cc1.COc1cccc(CN)c1>>CCOC(=O)Cc1ccc(OCc2csc3nc(C(=O)NCc4cccc(OC)c4)[nH]c(=O)c23)cc1 -US20060166933A1,7,CC(C)(C)[Si](C)(C)Oc1ccc2c(C3CCCC3)cc(=O)oc2c1>>CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)OC(O)C=C2C1CCCC1 -US20100069351A1,1,Cc1nsc(-c2ccc(Cl)nn2)n1.c1ccc2c(c1)CCC21CCNCC1>>Cc1nsc(-c2ccc(N3CCC4(CCc5ccccc54)CC3)nn2)n1 -US03953525,6,CCC1(c2ccc(C(O)C(C)(C)C)cc2)OCCO1>>CCC(=O)c1ccc(C(O)C(C)(C)C)cc1 -US09073922B2,1,C[Si](C)(C)CCOCCl.N#Cc1c[nH]c2nccc(Cl)c12>>C[Si](C)(C)CCOCn1cc(C#N)c2c(Cl)ccnc21 -US08129376B2,2,NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1.O=C(O)c1cc(-c2ccccc2C(F)(F)F)[nH]n1>>O=C(NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1)c1cc(-c2ccccc2C(F)(F)F)[nH]n1 -US20140038957A1,6,Cc1c[nH]c2ncnc(N3CCC(N(C)C(=O)OC(C)(C)C)CC3)c12>>CNC1CCN(c2ncnc3[nH]cc(C)c23)CC1 -US06248713B1,2,Nc1ccc(CC(=O)O)cc1.O=C=Nc1ccccc1>>O=C(O)Cc1ccc(NC(=O)Nc2ccccc2)cc1 -US06211199B1,1,COc1cc(CN2CCC(CCCOS(C)(=O)=O)(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC.c1ccc2[nH]c(NC3CCNCC3)nc2c1>>COc1cc(CN2CCC(CCCN3CCC(Nc4nc5ccccc5[nH]4)CC3)(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC -US20150259351A1,7,CCC(=O)C(C)n1c(C)c(C(=O)OC(C)(C)C)c2cccnc21>>CCC(O)C(C)n1c(C)c(C(=O)OC(C)(C)C)c2cccnc21 -US20090275664A1,1,BrCCCCCBr.Cc1cc(C)c(S(=O)(=O)Nc2c3ccccc3nc3ccccc23)c(C)c1>>Cc1cc(C)c(S(=O)(=O)N(CCCCCBr)c2c3ccccc3nc3ccccc23)c(C)c1 -US07232827B2,3,CC1(C)CN(CC2Cc3ccc(Cl)nc3C2)c2nc(-c3ccncn3)cc(=O)n2C1.OB(O)c1ccccc1>>CC1(C)CN(CC2Cc3ccc(-c4ccccc4)nc3C2)c2nc(-c3ccncn3)cc(=O)n2C1 -US20050107389A1,9,NO.O=C(c1ccc(C(F)(F)F)cc1F)C1CCN(Cc2ccccc2)CC1>>ON=C(c1ccc(C(F)(F)F)cc1F)C1CCN(Cc2ccccc2)CC1 -US07432258B2,1,CCOC(=O)C(C)(C)Br.Nc1ccc(Cl)c(Cl)c1>>CCOC(=O)C(C)(C)Nc1ccc(Cl)c(Cl)c1 -US05753664,1,Cn1ncc2[nH]c(Cl)c(Cl)c2c1=O.O=C(c1ccc(CBr)cc1)c1ccc(Cl)cc1Cl>>Cn1ncc2c(c(Cl)c(Cl)n2Cc2ccc(C(=O)c3ccc(Cl)cc3Cl)cc2)c1=O -US08049015B2,2,NCc1ccccc1.O=C(O)c1ccc(Br)c(CN(Cc2ccccc2)C(=O)C2CC2)c1>>O=C(NCc1ccccc1)c1ccc(Br)c(CN(Cc2ccccc2)C(=O)C2CC2)c1 -US05824691,2,COC(=O)c1cc(N)cc(-n2cccc2)c1.O=C(Br)CBr>>COC(=O)c1cc(NC(=O)CBr)cc(-n2cccc2)c1 -US20070254881A1,2,C1COCCN1.COc1ccc(-n2nc(C(=O)O)cc2-n2ccc(CO)c2)cn1>>COc1ccc(-n2nc(C(=O)N3CCOCC3)cc2-n2ccc(CO)c2)cn1 -US07030141B2,6,CO[C@@H]1C[C@H](C(=O)Nc2ccc(N3CCCCC3=O)cc2F)N(C(=O)OC(C)(C)C)C1>>CO[C@H]1CN[C@@H](C(=O)Nc2ccc(N3CCCCC3=O)cc2F)C1 -US09108938B2,2,NCC(c1cnc(C(F)(F)F)nc1)N1CCOCC1.O=C(O)c1cccc(Cl)c1Cl>>O=C(NCC(c1cnc(C(F)(F)F)nc1)N1CCOCC1)c1cccc(Cl)c1Cl -US20100305113A1,3,CC1(C)OB(c2ccc(C#N)nc2)OC1(C)C.CCOc1ccc(-c2ccc3nc(C)c(-c4ccc(Cl)nc4)n3n2)cc1OC>>CCOc1ccc(-c2ccc3nc(C)c(-c4ccc(-c5ccc(C#N)nc5)nc4)n3n2)cc1OC -US20130225552A1,1,Cn1c(=O)n([C@H]2C[C@H](N)C2)c2ncccc21.Cn1c(Cl)nc2ccccc21>>Cn1c(N[C@@H]2C[C@@H](n3c(=O)n(C)c4cccnc43)C2)nc2ccccc21 -US05068242,2,CCCCCCCCOC(=O)[C@@H]1C[C@@H]2CCC[C@@H]2N1.COC(=O)/C=C\C(=O)[O-]>>CCCCCCCCOC(=O)[C@@H]1C[C@@H]2CCC[C@@H]2N1C(=O)/C=C\C(=O)OC -US20090220607A1,9,Cc1cccc(Br)c1C(=O)O.[N-]=[N+]=[N-]>>Cc1cccc(N=[N+]=[N-])c1C(=O)O -US20100029707A1,7,N#CCc1cnn2ccc3c(c12)CCO3>>NCCc1cnn2ccc3c(c12)CCO3 -US20110112142A1,7,COc1ccc(-c2oc3c(C=O)cc(OC)cc3c2-c2ccccc2)cc1>>COc1ccc(-c2oc3c(CO)cc(OC)cc3c2-c2ccccc2)cc1 -US04436726,2,CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)O.NCCC(=O)N[C@@H](CO)C(=O)O>>CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)NCCC(=O)N[C@@H](CO)C(=O)O -US20140058100A1,2,O=C(O)Cc1cc(OCc2ccccc2)ccc1C(=O)O>>O=C1Cc2cc(OCc3ccccc3)ccc2C(=O)O1 -US20070293515A1,6,CC(C)(C)OC(=O)N[C@H]1CC[C@H](c2nc(-c3ccccc3)no2)C1>>N[C@H]1CC[C@H](c2nc(-c3ccccc3)no2)C1 -US08476253B2,6,CCOC(=O)CCNc1ccc(C(=O)N(C)CCCN(C)C(=O)OC(C)(C)C)cc1>>CN(CCCN(C)C(=O)c1ccc(NCCC(=O)O)cc1)C(=O)OC(C)(C)C -US20130053381A1,9,CCOC(=O)CCC(=O)Cl>>CCOC(=O)CCC=O -US20080287479A1,1,CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCNCC1.O=C(CCl)C1CCC(C(F)(F)F)CC1>>CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCN(CC(=O)C2CCC(C(F)(F)F)CC2)CC1 -US20020052376A1,7,Cn1cncc1CC(=O)c1nccs1>>Cn1cncc1CC(O)c1nccs1 -US08697685B2,2,Nc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CCCC(N)C2)n1.O=C(Cl)c1ccccc1>>Nc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CCCC(NC(=O)c3ccccc3)C2)n1 -US20120142665A1,2,CN(C)c1nc2cc(NC(=O)c3c(C(=O)O)cnn3C)ccn2n1.FC1CNC1>>CN(C)c1nc2cc(NC(=O)c3c(C(=O)N4CC(F)C4)cnn3C)ccn2n1 -US20100204231A1,1,C[C@H](Nc1nc(Cl)cc(N2CCOCC2)n1)c1ncc(F)cn1.Cc1cnc(N)s1>>Cc1cnc(Nc2cc(N3CCOCC3)nc(N[C@@H](C)c3ncc(F)cn3)n2)s1 -US07378417B2,2,Nc1cccc(S(=O)(=O)N2CCC[C@H]2CO)c1.O=C(O)c1cnn2c(C3CC3)cc(-c3ccc(Cl)cc3)nc12>>O=C(Nc1cccc(S(=O)(=O)N2CCC[C@H]2CO)c1)c1cnn2c(C3CC3)cc(-c3ccc(Cl)cc3)nc12 -US20070043076A1,3,O=C(CC(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1)Nc1cccc(C(F)(F)F)c1.O=Cc1cccc(C(F)(F)F)c1>>O=C(Nc1cccc(C(F)(F)F)c1)C(=Cc1cccc(C(F)(F)F)c1)C(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 -US20060052247A1,9,COC(=O)C1CC2C(=O)C(C(=O)c3ccc(C(F)F)nc3C)C(=O)C1C=C2Br>>COC(=O)C1CC2C=CC1C(=O)C(C(=O)c1ccc(C(F)F)nc1C)C2=O -US05614634,6,CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)OC)c2)n1>>CCCCCCCCC(O)/C=C/c1cccc(CC(O)c2cccc(C(=O)O)c2)n1 -US20090221555A1,1,BrCCBr.O=[N+]([O-])c1ccc(N2CCOCC2)cc1O>>O=[N+]([O-])c1ccc(N2CCOCC2)cc1OCCBr -US20140234254A1,3,Brc1ccn2ncc(I)c2c1.C#CCO>>OCC#Cc1cnn2ccc(Br)cc12 -US07919488B2,1,COCCBr.Fc1ccc(Cc2cc(-c3ccncc3)n[nH]2)cc1>>COCCn1nc(-c2ccncc2)cc1Cc1ccc(F)cc1 -US20120309734A1,6,COc1ccc(C2C(c3ccc(NC(=O)OCc4ccccc4)cc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1O>>COc1ccc(C2C(c3ccc(N)cc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1O -US20140329797A1,2,C1COCCN1.CC(C)(c1ccc(-c2noc(-c3ccc(=O)n(Cc4cccc(C(=O)Cl)c4)n3)n2)cc1)C(F)(F)F>>CC(C)(c1ccc(-c2noc(-c3ccc(=O)n(Cc4cccc(C(=O)N5CCOCC5)c4)n3)n2)cc1)C(F)(F)F -US05013738,6,C=C(CCCOC(C)=O)c1ccc(C(=O)OC)cc1>>C=C(CCCO)c1ccc(C(=O)OC)cc1 -US05599930,2,CCC(C)(C)Nc1cccnc1N1CCN(C(=O)c2cc3cc(N)ccc3[nH]2)CC1.CS(=O)(=O)Cl>>CCC(C)(C)Nc1cccnc1N1CCN(C(=O)c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)CC1 -US07795283B2,6,CC(C)(C)OC(=O)C1CCN(c2ccc(NC(=O)c3nnc(Nc4ccccc4F)o3)cn2)CC1>>O=C(Nc1ccc(N2CCC(C(=O)O)CC2)nc1)c1nnc(Nc2ccccc2F)o1 -US20090221555A1,1,CN([C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl)S(C)(=O)=O.CN1C(=O)CCC(C)(C)c2cc(N)ccc21>>CN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4N(C)S(C)(=O)=O)n3)ccc21 -US20100069629A1,6,COc1cccc(-c2nc(N3CCOCC3)nc3c2CCN3c2cccc(C#N)c2)c1>>N#Cc1cccc(N2CCc3c(-c4cccc(O)c4)nc(N4CCOCC4)nc32)c1 -US20050043315A1,1,CC(C)I.Nc1ncc(-c2ccc(=O)[nH]n2)c(-c2ccc(Cl)c(Cl)c2)n1>>CC(C)n1nc(-c2cnc(N)nc2-c2ccc(Cl)c(Cl)c2)ccc1=O -US20120029190A1,1,N#Cc1cc(Br)cc(F)c1F.c1ccc(-c2nc3c(o2)CCCNC3)nc1>>N#Cc1cc(N2CCCc3oc(-c4ccccn4)nc3C2)cc(F)c1F -US20040073037A1,2,CS(=O)(=O)Cl.O=C(NS(=O)(=O)N(Cc1ccccc1)CC1CCC(CO)CC1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CS(=O)(=O)OCC1CCC(CN(Cc2ccccc2)S(=O)(=O)NC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US20100331293A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.Cc1c(Cl)nc2c(Cl)c(F)cc(F)c2c1Cl>>Cc1c(-c2ccccn2)nc2c(Cl)c(F)cc(F)c2c1Cl -US20060287363A1,1,C=O.C[C@H]1C[C@@H](Nc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CCN1>>C[C@H]1C[C@@H](Nc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CCN1C -US20080176830A1,3,Cc1cc(B(O)O)ccc1F.O=C1CCc2cc(Br)ccc2N1>>Cc1cc(-c2ccc3c(c2)CCC(=O)N3)ccc1F -US20130096144A1,3,Cn1ncc(Cl)c1B1OC(C)(C)C(C)(C)O1.O=C1c2ccc(Br)nc2CN1[C@H](CO)Cc1cccc(F)c1>>Cn1ncc(Cl)c1-c1ccc2c(n1)CN([C@H](CO)Cc1cccc(F)c1)C2=O -US20080004330A1,8,CCOc1cc(Cl)ccc1CO>>CCOc1cc(Cl)ccc1C=O -US08889638B2,2,O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1.O=c1cccccc1O>>O=c1cccccc1OS(=O)(=O)c1ccc([N+](=O)[O-])cc1 -US20040058903A1,7,O=C(/C=C/c1ccc([N+](=O)[O-])cc1)c1ccccn1>>Nc1ccc(/C=C/C(=O)c2ccccn2)cc1 -US20120059002A1,6,COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCN4C(=O)c5ccccc5C4=O)c(C)c3)nc2n1>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCN)c(C)c3)nc2n1 -US07683079B2,6,CCOC(=O)[C@H]1CN(CCc2ccc(OC)c(OC)c2)CC[C@@H]1NC(=O)OC(C)(C)C>>CCOC(=O)[C@H]1CN(CCc2ccc(OC)c(OC)c2)CC[C@@H]1N -US20150266874A1,2,CC(C)N.CCOC(=O)c1c[nH]nc1-c1nc2ccccc2[nH]1>>CC(C)NC(=O)c1c[nH]nc1-c1nc2ccccc2[nH]1 -US20050277670A1,9,Cc1cccc(OC(c2ccc(Br)cc2)C2CCN(C(=O)OC(C)(C)C)CC2)n1.[C-]#N>>Cc1cccc(OC(c2ccc(C#N)cc2)C2CCN(C(=O)OC(C)(C)C)CC2)n1 -US20120269804A1,2,CC(C)(C)OC(=O)NS(=O)(=O)NCc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2N)c1.O=S(=O)(Cl)C1CC1>>CC(C)(C)OC(=O)NS(=O)(=O)NCc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2NS(=O)(=O)C2CC2)c1 -US04157331,9,COC(=O)c1cc(C(=O)OC)n(-c2ccc(Cl)cc2C(=O)c2ccccc2)n1.NO>>COC(=O)c1cc(C(=O)OC)n(-c2ccc(Cl)cc2C(=NO)c2ccccc2)n1 -US05998445,8,Cc1c(OCCOCc2ccccn2)ccnc1CSc1nc2ccccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>Cc1c(OCCOCc2ccccn2)ccnc1CS(=O)c1nc2ccccc2[nH]1 -US20080306045A1,6,CCOC(=O)C(C)N([C@H]1CCN(c2ccc3c(c2)CCCN(C(=O)OC(C)(C)C)C3)C1=O)S(=O)(=O)/C=C/c1ccc(Cl)s1>>CCOC(=O)[C@H](C)N([C@H]1CCN(c2ccc3c(c2)CCCNC3)C1=O)S(=O)(=O)/C=C/c1ccc(Cl)s1 -US08648074B2,1,FC(F)(F)c1ccc(Br)nc1.O=C1C(O)CC2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CCN12>>O=C1C(Oc2ccc(C(F)(F)F)cn2)CC2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CCN12 -US20100256156A1,6,COC(=O)c1ccc(OC(c2cc(-c3ccccc3)oc2C)C2CCOCC2)cc1>>Cc1oc(-c2ccccc2)cc1C(Oc1ccc(C(=O)O)cc1)C1CCOCC1 -US08466181B2,6,COC(=O)c1ccc(-n2cnc(-c3c(C)nnn3-c3ccccc3F)c2)nc1>>Cc1nnn(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)O)cn2)cn1 -US20110038876A1,8,CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc3c(Br)nn(C(c4ccccc4)(c4ccccc4)c4ccccc4)c3cc2CO)C1>>CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc3c(Br)nn(C(c4ccccc4)(c4ccccc4)c4ccccc4)c3cc2C=O)C1 -US20090118284A1,7,O=[N+]([O-])c1ccc2c(c1)c(-c1cc3cnccc3o1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>Nc1ccc2c(c1)c(-c1cc3cnccc3o1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C1CCSCC1>>CN(C(=O)N(C)[C@@H]1CN(C(=O)C2CCSCC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US08329732B2,2,CC1(C)C[C@@H](c2ccncc2N)C[C@@H](N2C(=O)c3ccccc3C2=O)C1.O=C(O)c1ccc(F)c(Br)n1>>CC1(C)C[C@@H](c2ccncc2NC(=O)c2ccc(F)c(Br)n2)C[C@@H](N2C(=O)c3ccccc3C2=O)C1 -US05646144,2,COc1cccc(C(=O)O)c1.O=C(N(Cc1ccnc2ccccc12)[C@H]1CCN[C@H](Cc2ccccc2)C1)C(F)(F)F>>COc1cccc(C(=O)N2CC[C@H](N(Cc3ccnc4ccccc34)C(=O)C(F)(F)F)C[C@H]2Cc2ccccc2)c1 -US08524917B2,1,CC(C)I.CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(O)cc2n1Cc1ccccc1>>CC(C)Oc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccc3)c2c1 -US06403601B1,6,COC(=O)c1c2c(cc(C#N)c1OC)CCCC2>>COc1c(C#N)cc2c(c1C(=O)O)CCCC2 -US20090023722A1,2,NCCCCCCCCn1cnc2c(N)nc3ccccc3c21.O=C(Cl)c1ccccc1>>Nc1nc2ccccc2c2c1ncn2CCCCCCCCNC(=O)c1ccccc1 -US20060089371A1,6,COC(=O)[C@H](Cc1ccccc1)Nc1cccc(-c2ccc(OCc3ccccc3)cc2)c1>>COC(=O)[C@H](Cc1ccccc1)Nc1cccc(-c2ccc(O)cc2)c1 -US06569890B2,4,CCOC(=O)C(CC(=O)c1ccccc1)C(C)=O.Nc1cccc([N+](=O)[O-])c1>>CCOC(=O)c1cc(-c2ccccc2)n(-c2cccc([N+](=O)[O-])c2)c1C -US20130158075A1,2,COC(=O)CCCc1nnc(-c2ccc(N)cc2)o1.O=C=Nc1cccc(C(F)(F)F)c1>>COC(=O)CCCc1nnc(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)o1 -US08445684B2,3,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc([Sn](C)(C)C)c1.Ic1cccc(OCCCc2ccccc2)c1>>CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc(-c2cccc(OCCCc3ccccc3)c2)c1 -US20110044943A1,3,Cc1noc(C)c1B(O)O.FC(F)(F)c1ccc(-c2cc(Cn3cc4nc(Br)nc-4cn3)on2)c(C(F)(F)F)c1>>Cc1noc(C)c1-c1nc2cnn(Cc3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)no3)cc-2n1 -US08003662B2,3,O=C(c1ccc(B(O)O)cc1)N1CCOCC1.O=c1c(-c2ccc(Oc3ccnc4cc(I)sc34)c(F)c2)cnc2n1CCN2c1ccccc1>>O=C(c1ccc(-c2cc3nccc(Oc4ccc(-c5cnc6n(c5=O)CCN6c5ccccc5)cc4F)c3s2)cc1)N1CCOCC1 -US20100152155A1,6,CCOC(=O)c1cnc(N2CC3C(CNCc4ccc5ccccc5c4)C3C2)nc1>>O=C(O)c1cnc(N2CC3C(CNCc4ccc5ccccc5c4)C3C2)nc1 -US20100331335A1,2,Nc1scc(Br)c1-c1ncn[nH]1.O=C(O)Cc1cccc2ncsc12>>O=C(Cc1cccc2ncsc12)Nc1scc(Br)c1-c1ncn[nH]1 -US08829058B2,6,CCOC(=O)Cc1ccc(OC)c(OCc2c(C)cccc2C)c1>>COc1ccc(CC(=O)O)cc1OCc1c(C)cccc1C -US20120238541A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(Cl)nccc4c3=O)cc2)CCC1.CS(=O)(=O)c1ccccc1B(O)O>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(-c5ccccc5S(C)(=O)=O)nccc4c3=O)cc2)CCC1 -US04609641,6,COC(=O)[C@H](CC(C)C)NCC[C@H](O)[C@H](CC(C)C)NC(=O)OC(C)(C)C>>CC(C)C[C@H](NCC[C@H](O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)C(=O)O -US20120214803A1,7,O=[N+]([O-])c1c(C(O)c2ccccc2)ccc2cccnc12>>Nc1c(C(O)c2ccccc2)ccc2cccnc12 -US20110059936A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cc2c(o1)CCNCC2>>CC(C)(C)OC(=O)N1CCc2ccoc2CC1 -US20130023541A1,1,CCNCc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1.CN(C)S(=O)(=O)c1ccccc1C=O>>CCN(Cc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1)Cc1ccccc1S(=O)(=O)N(C)C -US20110076291A1,2,CNC[C@H]1Cc2ccccc2O1.O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2>>CN(C[C@H]1Cc2ccccc2O1)C(=O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2 -US20030220324A1,2,CS(=O)(=O)Cl.Nc1ccccc1N1CCN(Cc2ccccc2)CC1>>CS(=O)(=O)Nc1ccccc1N1CCN(Cc2ccccc2)CC1 -US20110294781A1,1,C=C(C)c1cccc(C=O)c1.NNc1cc(N2CCOCC2)n2nc(-c3ccncc3)cc2n1>>C=C(C)c1cccc(C=NNc2cc(N3CCOCC3)n3nc(-c4ccncc4)cc3n2)c1 -US20090275538A1,3,O=C1CSC(=S)N1.O=Cc1cc(F)ccc1O>>O=C1NC(=S)S/C1=C\c1cc(F)ccc1O -US05342846,6,CC(C)(C)OC(=O)N1C[C@@H](N)[C@@H](n2ccnn2)C1>>N[C@@H]1CNC[C@@H]1n1ccnn1 -US20050182101A1,2,Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1.O=C(COc1ccc(S(=O)(=O)Cl)cc1OCC(=O)OCCS(=O)(=O)c1ccccc1)OCCS(=O)(=O)c1ccccc1>>Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2n1S(=O)(=O)c1ccc(OCC(=O)OCCS(=O)(=O)c2ccccc2)c(OCC(=O)OCCS(=O)(=O)c2ccccc2)c1 -US20070123504A1,2,COCCN(C)c1ccc(N)cn1.O=C(O)c1nc(C2CCCCC2)oc1C(F)(F)F>>COCCN(C)c1ccc(NC(=O)c2nc(C3CCCCC3)oc2C(F)(F)F)cn1 -US06982348B2,1,CC(C)I.O=C(NC(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(O)cc1)c1cccc2c1C=CCCC2>>CC(C)Oc1ccc(C(O)C(Cc2cccc(OC(F)(F)C(F)F)c2)NC(=O)c2cccc3c2C=CCCC3)cc1 -US08906889B2,1,C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(C(=O)OCC)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.OCCBr>>C=C(C)[C@@H]1CC[C@]2(NCCO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(C(=O)OCC)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20040242572A1,1,N#CCc1ccc(CBr)cc1.c1ccc(C2CCNCC2)cc1>>N#CCc1ccc(CN2CCC(c3ccccc3)CC2)cc1 -US20100210642A1,3,C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12.OCc1ccc(Br)cc1>>OCc1ccc(C#Cc2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)cc1 -US07282495B2,1,Brc1cccc2nc[nH]c12.C1CNCCNC1>>c1cc(N2CCCNCC2)c2[nH]cnc2c1 -US20100063249A1,1,CCCCNc1nc(Cl)nc(NCCCC)n1.NCCO>>CCCCNc1nc(NCCO)nc(NCCCC)n1 -US05834471,1,CCOC(=O)N1CCNCC1.CCOC(=O)c1ccc(F)cc1>>CCOC(=O)c1ccc(N2CCN(C(=O)OCC)CC2)cc1 -US20140363452A1,6,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](N)C(C)C -US20060049397A1,2,CC(=O)OC(C)=O.CC(C)c1ccc(N)cc1>>CC(=O)Nc1ccc(C(C)C)cc1 -US20070037787A1,1,BrCc1ccc(CBr)cc1.COc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(O)cc2)cc1>>COc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(OCc3ccc(CBr)cc3)cc2)cc1 -US04892873,1,CC(=O)Nc1cccc(-c2ccc(Cl)nn2)c1.CI>>CC(=O)N(C)c1cccc(-c2ccc(Cl)nn2)c1 -US20090275567A1,2,CC(=O)OC(C)=O.Cc1ncc(-c2ccnc(NC3CCNCC3)n2)n1C(C)C>>CC(=O)N1CCC(Nc2nccc(-c3cnc(C)n3C(C)C)n2)CC1 -US20150148337A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1noc2c1-c1ccc(Cl)cc1C(=O)N[C@H]2CC(=O)OC(C)(C)C>>Cc1noc2c1-c1ccc(Cl)cc1C(=O)N(C(=O)OC(C)(C)C)[C@H]2CC(=O)OC(C)(C)C -US20140296252A1,3,Cc1nc(-n2nc(-c3ccc(F)cc3)[nH]c2=O)ccc1Oc1ccnc(Cl)c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cc1nc(-n2nc(-c3ccc(F)cc3)[nH]c2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1 -US20100184800A1,6,COC(=O)c1cc(-c2ccn3nc(-c4ccc(F)cc4)c(C(=O)N(C)C(=O)OC(C)(C)C)c3c2F)c(C)nc1OC>>CNC(=O)c1c(-c2ccc(F)cc2)nn2ccc(-c3cc(C(=O)OC)c(OC)nc3C)c(F)c12 -US20140343086A1,1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1.O[C@H]1CCNC1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@H](O)C2)c(Br)c1 -US20070219187A1,2,CN1CCNCC1c1nc(-c2ccc(F)cc2)no1.O=C(Cl)c1ccc(F)cc1>>CN1CCN(C(=O)c2ccc(F)cc2)CC1c1nc(-c2ccc(F)cc2)no1 -US20090186900A1,3,CC(=O)OC(C)=O.COc1ccc(-c2ccccc2C)cc1>>COc1ccc(-c2ccc(C(C)=O)cc2C)cc1 -US20120040981A1,3,CC1(C)NC(=O)c2sc(Br)cc2N1.CC1(C)OB(c2ccnc(F)c2)OC1(C)C>>CC1(C)NC(=O)c2sc(-c3ccnc(F)c3)cc2N1 -US08975443B2,1,CCCCO.COc1ccccc1Cl>>CCCCOc1ccccc1OC -US07504522B2,2,Cc1ccc(C(OC2CNC2)c2ccccc2C(F)(F)F)cc1.O=C=NC12CC3CC(CC(C3)C1)C2>>Cc1ccc(C(OC2CN(C(=O)NC34CC5CC(CC(C5)C3)C4)C2)c2ccccc2C(F)(F)F)cc1 -US08202885B2,2,CC(=O)O.COc1ccc(Cl)c(N)c1>>COc1ccc(Cl)c(NC(C)=O)c1 -US20100120789A1,4,C#CCN(C)Cc1cccs1.[N-]=[N+]=NC12CC3CC(CC(C3)C1)C2>>CN(Cc1cn(C23CC4CC(CC(C4)C2)C3)nn1)Cc1cccs1 -US05278154,2,COC(=O)[C@@H](N)Cc1ccccc1.O=Cc1cc(C(=O)O)ccc1O>>COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(O)c(C=O)c1 -US20130053409A1,1,COc1cc(C2=CCN(C)CC2)c([N+](=O)[O-])cc1N.O=S(=O)(c1ccccc1)n1cc(-c2nc(Cl)ncc2Cl)c2ccccc21>>COc1cc(C2=CCN(C)CC2)c([N+](=O)[O-])cc1Nc1ncc(Cl)c(-c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)n1 -US20040106635A1,2,CCN1CCc2cc(OC)c(OC)cc2C1C1CC(C(=O)N2CCN(c3ncnc4c3cnn4Cc3ccncc3)CC2)CCC12c1cc(OC)c(OC)cc1CCN2C(=O)CCNC.O=CO>>CCN1CCc2cc(OC)c(OC)cc2C1C1CC(C(=O)N2CCN(c3ncnc4c3cnn4Cc3ccncc3)CC2)CCC12c1cc(OC)c(OC)cc1CCN2C(=O)CCN(C)C=O -US07517884B2,7,COC(=O)c1cnc(Cl)cc1Cl>>OCc1cnc(Cl)cc1Cl -US20060063784A1,1,BrCC1CCC1.O=C(c1cccs1)c1cnn2c(-c3cccc(-c4cc[nH]n4)c3)ccnc12>>O=C(c1cccs1)c1cnn2c(-c3cccc(-c4ccn(CC5CCC5)n4)c3)ccnc12 -US08754085B2,6,CC(=O)O[C@@H]1CCN(C(=O)OC(C)(C)C)c2nc(-c3ccccc3)c(-c3ccccc3)nc21>>CC(=O)O[C@@H]1CCNc2nc(-c3ccccc3)c(-c3ccccc3)nc21 -US20090216044A1,1,N.O=C(O)CCC(=O)C(=O)O>>N[C@@H](CCC(=O)O)C(=O)O -US20140200227A1,2,CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(N)cnc3ccccc23)C1.CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)O>>CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnc2ccccc2c1N1CCC[C@H](NC(=O)OC(C)(C)C)C1 -US20030004196A1,2,CCOC(=O)C(N)Cc1cc(C2CCCN2C(=O)OC(C)(C)C)no1.O=C(Cl)c1c(Cl)cccc1Cl>>CCOC(=O)C(Cc1cc(C2CCCN2C(=O)OC(C)(C)C)no1)NC(=O)c1c(Cl)cccc1Cl -US20050130989A1,3,CC[Mg+].COc1cc(OC)cc(N2CCN(C(=O)c3cc(C=O)nn3-c3ccccc3)CC2)c1>>CCC(O)c1cc(C(=O)N2CCN(c3cc(OC)cc(OC)c3)CC2)n(-c2ccccc2)n1 -US20080096930A1,7,CCCc1c(OCc2ccc([N+](=O)[O-])cc2)ccc(C(C)=O)c1O>>CCCc1c(OCc2ccc(N)cc2)ccc(C(C)=O)c1O -US20130331378A1,7,COC(=O)c1cccc(C(=O)c2c(-c3cccnc3)nn3cc(OC)ccc23)n1>>COC(=O)c1cccc(C(O)c2c(-c3cccnc3)nn3cc(OC)ccc23)n1 -US20050107375A1,1,CN(C)C1CCNCC1.Cc1ccccc1-c1cc(Cl)nc2c1C(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)CCCO2>>Cc1ccccc1-c1cc(N2CCC(N(C)C)CC2)nc2c1C(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)CCCO2 -US20130023532A1,1,CI.CS(=O)(=O)c1cc([N+](=O)[O-])ccc1O>>COc1ccc([N+](=O)[O-])cc1S(C)(=O)=O -US08344135B2,7,CC(C)(C#N)c1cccc(C(=O)Nc2cccc([N+](=O)[O-])c2)c1>>CC(C)(C#N)c1cccc(C(=O)Nc2cccc(N)c2)c1 -US09067898B1,7,C=C(C)c1snc(-c2ccc(CC)cc2)c1COc1ccc(CCC(=O)OCC)c(C)c1C>>CCOC(=O)CCc1ccc(OCc2c(-c3ccc(CC)cc3)nsc2C(C)C)c(C)c1C -US20120190666A1,1,CCCC[Sn](CCCC)(CCCC)c1cc(Cl)nc(C)n1.C[S-]>>CCCC[Sn](CCCC)(CCCC)c1cc(SC)nc(C)n1 -US07625908B2,1,C[C@@H](COc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12)N(C)C(=O)CO.ClCc1ccccn1>>C[C@@H](COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)N(C)C(=O)CO -US20060189661A1,9,Brc1cccc(-c2nc(-c3ccccn3)co2)c1.[C-]#N>>N#Cc1cccc(-c2nc(-c3ccccn3)co2)c1 -US20140066406A1,1,CN1CCNCC1.CP(C)(=O)c1ccc(Nc2ncnc(Cl)n2)cc1>>CN1CCN(c2ncnc(Nc3ccc(P(C)(C)=O)cc3)n2)CC1 -US20100210636A1,7,COc1ccc(CN2C(=O)N(C)C(C[N+](=O)[O-])(C(F)(F)F)c3cc(Br)ccc32)cc1>>COc1ccc(CN2C(=O)N(C)C(CN)(C(F)(F)F)c3cc(Br)ccc32)cc1 -US20090247618A1,6,Clc1ccc(OCc2ccccc2)c(OC[C@H]2CO2)c1>>Oc1ccc(Cl)cc1OC[C@H]1CO1 -US06451836B1,6,O=C1c2ccccc2C(=O)N1CCN1C[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1COCc1ccccc1>>NCCN1C[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1COCc1ccccc1 -US20080051578A1,2,Cc1cc(-n2cnc(CNC(=O)c3ccc(Cl)s3)c2)ccc1N.O=C(O)CCCCCl>>Cc1cc(-n2cnc(CNC(=O)c3ccc(Cl)s3)c2)ccc1NC(=O)CCCCCl -US06313148B1,1,CCN.O=C(O)c1ccc(Cl)nc1>>CCNc1ccc(C(=O)O)cn1 -US20080058546A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1(CC(=O)O)CCCCC1>>CC(C)(C)OC(=O)NCC1(CC(=O)O)CCCCC1 -US05283244,1,N#Cc1cc([N+](=O)[O-])c(N)cc1F.c1c[nH]cn1>>N#Cc1cc([N+](=O)[O-])c(N)cc1-n1ccnc1 -US20090227588A1,2,Nc1ncc(-n2nc(C(F)(F)F)cc2-c2cccnc2)cn1.O=C(Cl)c1ccccc1>>O=C(Nc1ncc(-n2nc(C(F)(F)F)cc2-c2cccnc2)cn1)c1ccccc1 -US08883782B2,3,NC1=NC2(CO1)c1cc(Br)ccc1Oc1nc(F)ccc12.OB(O)c1cccnc1F>>NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1nc(F)ccc12 -US06962933B1,2,Cc1cc(C)cc(-c2nc(N)sc2-c2ccncc2)c1.O=C(Cl)c1ccncc1>>Cc1cc(C)cc(-c2nc(NC(=O)c3ccncc3)sc2-c2ccncc2)c1 -US20110152316A1,7,CC(C)(C)OC(=O)N(Cc1cc(C=O)cc(Cl)c1Cl)C1CC1>>CC(C)(C)OC(=O)N(Cc1cc(CO)cc(Cl)c1Cl)C1CC1 -US20050107449A1,7,Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(C)C=O>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(C)CO -US20120035214A1,6,CC(C)(C)[Si](C)(C)OCC(F)(F)COCc1ccc(Br)cc1>>OCC(F)(F)COCc1ccc(Br)cc1 -US08501992B2,2,CC(C)(C)OC(=O)NCc1cccc(CNCc2ccc(Oc3ccc(F)cc3)cc2)c1.O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1O>>CC(C)(C)OC(=O)NCc1cccc(CN(Cc2ccc(Oc3ccc(F)cc3)cc2)S(=O)(=O)c2cc(Cl)cc(Cl)c2O)c1 -US08119624B2,6,COC(=O)c1cc(OC)cc2occc12>>COC(=O)c1cc(O)cc2occc12 -US20070003539A1,6,COC(=O)C[C@@H](NC(=O)OC(C)(C)C)c1cc(NC(=O)OC)ccc1S(=O)(=O)C(C)C>>COC(=O)C[C@@H](N)c1cc(NC(=O)OC)ccc1S(=O)(=O)C(C)C -US20150057281A1,4,COc1cc(OC)c(C(=O)CBr)c(OC)c1.NC(N)=S>>COc1cc(OC)c(-c2csc(N)n2)c(OC)c1 -US05273999,1,C#CCCCCO.COC(=O)CCc1ccccc1O>>C#CCCCCOc1ccccc1CCC(=O)OC -US07855216B2,2,CC1(C)OC[C@H](CON)O1.CCOC(=O)c1c(Nc2ccc(I)cc2F)c2cnccc2n1C>>Cn1c(C(=O)NOC[C@H]2COC(C)(C)O2)c(Nc2ccc(I)cc2F)c2cnccc21 -US06426413B1,6,C=CCOc1c(Cl)cc(C(=O)NC2CCC(=O)N(C)N(C(C)C(=O)OCC)C2=O)cc1Cl>>C=CCOc1c(Cl)cc(C(=O)NC2CCC(=O)N(C)N(C(C)C(=O)O)C2=O)cc1Cl -US08247436B2,2,COc1nc(C(=O)O)c(-n2c(C)ccc2C)cc1C(F)(F)F.NCC(O)C(F)(F)F>>COc1nc(C(=O)NCC(O)C(F)(F)F)c(-n2c(C)ccc2C)cc1C(F)(F)F -US20050282864A1,1,CC(C)N1CCC(O)C1.CCOC(=O)c1cc2cc(O)ccc2[nH]1>>CCOC(=O)c1cc2cc(OC3CCN(C(C)C)C3)ccc2[nH]1 -US04874775,2,CS(=O)(=O)Cl.O=[N+]([O-])c1cccc(NCc2cccnc2)c1>>CS(=O)(=O)N(Cc1cccnc1)c1cccc([N+](=O)[O-])c1 -US20080234263A1,1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1C(=O)O2 -US20080287517A1,6,Cc1ccc(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(OCc4ccccc4)cc3)c2C)nc1>>Cc1ccc(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(O)cc3)c2C)nc1 -US07960415B2,2,CC(C)(C)OC(=O)CC(N)C(O)COc1c(F)c(F)cc(F)c1F.CC[C@@H](C(=O)O)n1cccc(NC(C)=O)c1=O>>CCC(C(=O)N[C@@H](CC(=O)OC(C)(C)C)[C@H](O)COc1c(F)c(F)cc(F)c1F)n1cccc(NC(C)=O)c1=O -US06953809B2,1,CCOC(=O)c1cc2ccccc2[nH]1.ClCc1ccc(Cl)cc1>>CCOC(=O)c1cc2ccccc2n1Cc1ccc(Cl)cc1 -US08969336B2,1,CN1CCNCC1.COc1ccc([N+](=O)[O-])cc1N1CCC(=O)CC1>>COc1ccc([N+](=O)[O-])cc1N1CCC(N2CCN(C)CC2)CC1 -US20120040936A1,3,CC(C)(C)OC(=O)N1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.C[Si](C)(C)CCOC(=O)c1ccc2cncc(OS(=O)(=O)C(F)(F)F)c2c1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cncc4ccc(C(=O)OCC[Si](C)(C)C)cc34)cc2)CC1 -US20080255106A1,6,COC(=O)c1ccc(-c2nc3c(Cl)ccnc3[nH]2)cc1>>O=C(O)c1ccc(-c2nc3c(Cl)ccnc3[nH]2)cc1 -US20050038098A1,6,COc1c(F)cc(C2OCCO2)c(F)c1-c1cc2c(cc1C)C(C)(C)CC=C2C(C)C>>COc1c(F)cc(C=O)c(F)c1-c1cc2c(cc1C)C(C)(C)CC=C2C(C)C -US04568687,2,NCCCn1ccnc1.O=C(O)CCc1ccccc1>>O=C(CCc1ccccc1)NCCCn1ccnc1 -US20080249150A1,9,CCC(CC)C(N=[N+]=[N-])c1ncnn1Cc1ccc(F)cc1>>CCC(CC)C(N)c1ncnn1Cc1ccc(F)cc1 -US20140275025A1,1,C1COCCN1.O=C1CCc2c(ccc(Br)c2F)C1>>Fc1c(Br)ccc2c1CCC(N1CCOCC1)C2 -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.OB(O)c1ccc(Cl)cc1>>COc1ccc2c(-c3ccc(Cl)cc3)nc(Nc3cc(C)[nH]n3)cc2c1 -US08481725B2,1,C1COCCN1.COC(=O)C1(NC(=O)c2ccc(CCl)cc2)CCCCC1>>COC(=O)C1(NC(=O)c2ccc(CN3CCOCC3)cc2)CCCCC1 -US07662581B1,6,Cc1ccc(C(=O)N(CCCN2C(=O)c3ccccc3C2=O)C(c2nc3cc(Br)ccc3n2Cc2ccccc2)C(C)C)cc1>>Cc1ccc(C(=O)N(CCCN)[C@@H](c2nc3cc(Br)ccc3n2Cc2ccccc2)C(C)C)cc1 -US07691874B2,2,CC(C)(C)C(=O)Cl.CC(C)(C)OC(=O)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc13>>CC(C)(C)OC(=O)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(OC(=O)C(C)(C)C)cc13 -US20130261130A1,7,COC(=O)c1ccc(Br)cc1[N+](=O)[O-]>>COC(=O)c1ccc(Br)cc1N -US09150544B2,7,COC(=O)/C(=C\c1cc2ccnc(NC(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1OC(F)(F)F)N1CC[C@H](NC(=O)OC(C)(C)C)C1=O>>COC(=O)[C@@H](Cc1cc2ccnc(NC(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1OC(F)(F)F)N1CC[C@H](NC(=O)OC(C)(C)C)C1=O -US20140296246A1,3,CCC(C)[Mg+].CCOc1nc2c(C(=O)c3ccccn3)cc(-c3c(C)noc3C)cc2[nH]1>>CCOc1nc2c(C(O)(c3ccccn3)C(C)CC)cc(-c3c(C)noc3C)cc2[nH]1 -US20090306077A1,1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(CO)cc1.CN1CCN(CCCN)CC1>>CN1CCN(CCCNCc2ccc(C(=O)Nc3ccccc3NC(=O)OC(C)(C)C)cc2)CC1 -US20080293716A1,2,Cc1cccc(CN)c1.O=C(O)c1ccc(-c2ccncc2)s1>>Cc1cccc(CNC(=O)c2ccc(-c3ccncc3)s2)c1 -US06271225B1,1,CCOC(=O)c1c(N)sc2cc(OC)ccc12.O=[N+]([O-])c1ccccc1F>>CCOC(=O)c1c(Nc2ccccc2[N+](=O)[O-])sc2cc(OC)ccc12 -US04816466,6,CCOC(=O)[C@@H](CCCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@@H](C)C(=O)OC(C)(C)C>>CCOC(=O)[C@@H](CCCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@@H](C)C(=O)O -US08088815B2,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12.COC(=O)c1cccc(N)c1>>COC(=O)c1cccc(NC(=O)[C@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c1 -US04065584,1,ClCCCCBr.Sc1ccccc1>>ClCCCCSc1ccccc1 -US06992083B2,1,C1COCCN1.COc1ccc(C2CCOCC2)c2oc(NC(=O)c3ccnc(Br)c3)nc12>>COc1ccc(C2CCOCC2)c2oc(NC(=O)c3ccnc(N4CCOCC4)c3)nc12 -US07544690B2,6,CC(C)(C)OC(=O)NC[C@@H]1CC[C@H](CNC(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@H](CN)CC1 -US20100137276A1,2,O=C(O)c1ccc(-n2nc(C(F)(F)F)c3c2CCOC3)cc1F.OC1CNC1>>O=C(c1ccc(-n2nc(C(F)(F)F)c3c2CCOC3)cc1F)N1CC(O)C1 -US07935721B2,1,ClCc1ccc(-c2cccc(Cl)c2)o1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCO3>>O=C1N(Cc2ccc(-c3cccc(Cl)c3)o2)c2ccccc2C12COc1cc3c(cc12)OCO3 -US20140140956A1,1,CC(C)(C)[Si](C)(C)OCCBr.O=Cc1ccc(O)c(-c2ccccc2)n1>>CC(C)(C)[Si](C)(C)OCCOc1ccc(C=O)nc1-c1ccccc1 -US07625908B2,1,C[C@@H](COc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12)NC(=O)CO.ClCc1ccccn1>>C[C@@H](COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)NC(=O)CO -US05306712,3,C[Si](C)(C)C[Mg+].O=C(Cn1cncn1)c1ccccc1>>C[Si](C)(C)CC(O)(Cn1cncn1)c1ccccc1 -US20080275028A1,3,O=C(NCCCCN1CCOCC1)Nc1ccc(Br)cc1.OB(O)c1ccccc1Cl>>O=C(NCCCCN1CCOCC1)Nc1ccc(-c2ccccc2Cl)cc1 -US20050164989A1,6,NN1CCCC(NC(=O)OCc2ccccc2)([PH](=O)NC(=O)COc2ccccc2)C1=O>>NN1CCCC(N)([PH](=O)NC(=O)COc2ccccc2)C1=O -US06448278B2,2,CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1.CNC>>CN(C)C(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1 -US20040122028A1,1,Cn1c(=O)c2c(CO)c(Cc3ccccc3C(F)(F)F)sc2n(CC2CC2)c1=O.Oc1ccccc1>>Cn1c(=O)c2c(COc3ccccc3)c(Cc3ccccc3C(F)(F)F)sc2n(CC2CC2)c1=O -US20140323478A1,1,CCn1c(=O)c(-c2ccc(Br)cc2Cl)cc2cnc(SC)nc21.O=S([O-])C1CC1>>CCn1c(=O)c(-c2ccc(S(=O)(=O)C3CC3)cc2Cl)cc2cnc(SC)nc21 -US20080096903A1,3,C#CCn1c(Cc2cc3c(cc2I)OCO3)nc2c(N)nc(F)nc21.C=O.OC1CCNC1>>Nc1nc(F)nc2c1nc(Cc1cc3c(cc1I)OCO3)n2CC#CCN1CCC(O)C1 -US06403055B1,2,N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.O=C(Cl)OCc1ccccc1>>O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)OCc1ccccc1 -US07256198B2,2,CC1(C)CN=C2N(C1)c1ccc(S(=O)(=O)N3CCC[C@H]3CO)cc1C21OCCCO1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@@H]2CCCN2S(=O)(=O)c2ccc3c(c2)C2(OCCCO2)C2=NCC(C)(C)CN23)cc1 -US20050197350A1,6,COC(=O)c1cccc(C(=O)N[C@@H]2CC[C@H](Nc3ccc4ccccc4n3)CC2)c1>>O=C(O)c1cccc(C(=O)N[C@@H]2CC[C@H](Nc3ccc4ccccc4n3)CC2)c1 -US20150183784A1,3,CS(=O)(=O)Cc1ncc(OCC2CC2)c(Cl)n1.Cn1cc(-c2ccc3c(=O)n(C)cc(B4OC(C)(C)C(C)(C)O4)c3c2)cn1>>Cn1cc(-c2ccc3c(=O)n(C)cc(-c4nc(CS(C)(=O)=O)ncc4OCC4CC4)c3c2)cn1 -US20040106795A1,1,COc1ccc(B(O)O)cc1.OCc1cc(Cl)c(O)c(Cl)c1>>COc1ccc(Oc2c(Cl)cc(CO)cc2Cl)cc1 -US20140275129A1,2,COc1ccc2c(c1O)CCNC2.O=C(O)c1nc(-c2cccnc2)nc2ccccc12>>COc1ccc2c(c1O)CCN(C(=O)c1nc(-c3cccnc3)nc3ccccc13)C2 -US05366987,3,CCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.CCOC(=O)C(c1ccccc1)n1cc(C=O)cn1>>CCCCCCCCCCC=Cc1cnn(C(C(=O)OCC)c2ccccc2)c1 -US05541317,1,CCC(=O)Cl.Sc1ccc2ccccc2n1>>CCC(=O)Sc1ccc2ccccc2n1 -US08324176B2,2,CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCO)cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O.CS(=O)(=O)Cl>>CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCOS(C)(=O)=O)cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O -US20100279995A1,1,CCNCCNCC.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCNCCN(CC)C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20070219196A1,2,CCCN.CCCc1nc2cnc3ccccc3c2n1CCCCCC(=O)O>>CCCNC(=O)CCCCCn1c(CCC)nc2cnc3ccccc3c21 -US20090069282A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.CC1(C)CCCC(C)(C)N1CCOc1ccc(I)cc1>>CC1(C)CCCC(C)(C)N1CCOc1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1 -US20140364433A1,3,CB1OB(C)OB(C)O1.Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc3cc(Br)ccc3n2)c1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc3cc(C)ccc3n2)c1 -US06015825,1,O=C(Cc1ccc(F)cc1F)c1ccc(F)cc1.c1nc[nH]n1>>O=C(Cc1ccc(F)cc1F)c1ccc(-n2cncn2)cc1 -US20100216758A1,1,CCCNC.COc1cc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)ccc1CO>>CCCN(C)Cc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1OC -US07572817B2,1,COc1ccc(CSC(CCc2cccc(O)c2)C(Cc2ccc(NC(=O)OC(C)(C)C)nc2)C(=O)OC(C)(C)C)cc1.OC1CCOC1>>COc1ccc(CSC(CCc2cccc(OC3CCOC3)c2)C(Cc2ccc(NC(=O)OC(C)(C)C)nc2)C(=O)OC(C)(C)C)cc1 -US05057614,8,CSCCCn1cc(C2=C(c3cn(C)c4ccccc34)C(=O)NC2=O)c2ccccc21.O=C(OO)c1cccc(Cl)c1>>Cn1cc(C2=C(c3cn(CCCS(C)=O)c4ccccc34)C(=O)NC2=O)c2ccccc21 -US20130289072A1,1,COc1ccc(CCl)cc1.Cc1c[nH]c2cccc(Br)c12>>COc1ccc(Cn2cc(C)c3c(Br)cccc32)cc1 -US20120108577A1,1,COc1ccc2c(c1)N(CC[C@@H]1CC[C@@H](N)CC1)C(=O)CO2.O=Cc1ccc2c(n1)NC(=O)CO2>>COc1ccc2c(c1)N(CC[C@@H]1CC[C@@H](NCc3ccc4c(n3)NC(=O)CO4)CC1)C(=O)CO2 -US20050137236A1,3,CC(C)(C)OC(=O)N(CCCc1ccc(Br)cc1)C[C@H](O)c1cccnc1.COC(=O)c1ccc(B(O)O)cc1OCC(C)C>>COC(=O)c1ccc(-c2ccc(CCCN(C[C@H](O)c3cccnc3)C(=O)OC(C)(C)C)cc2)cc1OCC(C)C -US20090227588A1,4,NNc1ccc(NC(=O)C2CCCCC2)nc1.O=C(CC(=O)C(F)(F)F)c1cccnc1>>O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2-c2cccnc2)cn1)C1CCCCC1 -US06794402B2,1,NCCCc1ccc(Cl)cc1F.O=C1CCC(c2ccc3[nH]c(=O)oc3c2)CC1>>O=c1[nH]c2ccc([C@@H]3CC[C@@H](NCCCc4ccc(Cl)cc4F)CC3)cc2o1 -US20150051395A1,6,CC(C)(C)NC(=O)c1ccc(S(=O)(=O)Nc2cc(F)c(C(=O)OCc3ccccc3)c(F)c2)cn1>>CC(C)(C)NC(=O)c1ccc(S(=O)(=O)Nc2cc(F)c(C(=O)O)c(F)c2)cn1 -US07973078B2,1,COc1ccc(CNC(=O)CBr)cc1.Cc1c(Cl)cccc1NS(=O)(=O)c1ccc(F)cc1>>COc1ccc(CNC(=O)CN(c2cccc(Cl)c2C)S(=O)(=O)c2ccc(F)cc2)cc1 -US20070265193A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)N(C(=O)CN1C(=O)C(Cc2c[nH]c3ccccc23)c2nnc(-c3ccccc3)n2-c2ccccc21)c1ccccc1>>CC(C)N(C(=O)CN1C(=O)C(Cc2cn(C(=O)OC(C)(C)C)c3ccccc23)c2nnc(-c3ccccc3)n2-c2ccccc21)c1ccccc1 -US20070049581A1,6,CCOC(=O)[C@@H]1CN(C2CCN(C)CC2)CCN1C(=O)[C@@H](Cc1cc(Cl)c(N)c(C(F)(F)F)c1)OC(=O)N1CCC(N2CCc3ccccc3NC2=O)CC1>>CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(Cl)c(N)c(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)[C@H](C(=O)O)C2)CC1 -US07727988B2,3,COc1ncc(B(O)O)c(OC)n1.Cc1ccc(Br)cn1>>COc1ncc(-c2ccc(C)nc2)c(OC)n1 -US06875765B2,1,CCOC(OCC)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(N)cc1O.CSc1nc2ccccc2n1C[C@H](C)O>>CCOC(OCC)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(N)cc1O[C@H](C)Cn1c(SC)nc2ccccc21 -US20030083359A1,3,O=C(O)c1cc(C(=O)O)c(C(=O)N(Cc2cccc(Br)c2)[C@H]2CCCc3ccccc32)cc1C(=O)O.OB(O)c1ccc(Cl)cc1>>O=C(O)c1cc(C(=O)O)c(C(=O)N(Cc2cccc(-c3ccc(Cl)cc3)c2)[C@H]2CCCc3ccccc32)cc1C(=O)O -US20140315856A1,7,O=[N+]([O-])c1ccc(Cl)c(OCC2CC2)c1>>Nc1ccc(Cl)c(OCC2CC2)c1 -US06294549B1,1,CCOC(=O)C1CCNCC1.Clc1ccncc1>>CCOC(=O)C1CCN(c2ccncc2)CC1 -US20090099176A1,7,COC(=O)C(=Cc1cccnc1NC(=O)C(C)(C)C)NC(=O)OC(C)(C)C>>COC(=O)C(Cc1cccnc1NC(=O)C(C)(C)C)NC(=O)OC(C)(C)C -US08334287B2,9,Cc1nc(I)c(I)n1-c1cnn(C)c(=O)c1>>Cc1nc(I)cn1-c1cnn(C)c(=O)c1 -US05912353,4,CCC1=[SH]C(=N)N(Cc2ccc(-c3ccccc3C#N)cc2)N1.[N-]=[N+]=[N-]>>CCC1=[SH]C(=N)N(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)N1 -US08846741B2,2,CC(C)(C)OC(=O)NC1CCc2ccc(CN)cc2C1Cc1ccccc1.O=S(=O)(Cl)C1CCC1>>CC(C)(C)OC(=O)NC1CCc2ccc(CNS(=O)(=O)C3CCC3)cc2C1Cc1ccccc1 -US20100009956A1,2,N#Cc1ncc(Br)c(N(N)C2CCCC2)n1.O=C(Cl)c1cccc(CCl)c1>>N#Cc1ncc(Br)c(N(NC(=O)c2cccc(CCl)c2)C2CCCC2)n1 -US07932270B2,2,CC(C)(C)OC(=O)N1CC[C@@H]1CN.Cn1cc(-c2nc(NCCc3cccc(F)c3)c(C(=O)O)cc2F)cn1>>Cn1cc(-c2nc(NCCc3cccc(F)c3)c(C(=O)NC[C@H]3CCN3C(=O)OC(C)(C)C)cc2F)cn1 -US20080139631A1,2,N#Cc1ccc2c(cc(C(F)F)n2CC(=O)O)c1Cl.NN>>N#Cc1ccc2c(cc(C(F)F)n2CC(=O)NN)c1Cl -US20050090534A1,2,CN1CCC(CN2CCNCC2)CC1.Cc1cc(C)n(-c2nc(-c3ccc(Cl)cc3)c(CCC(=O)O)o2)n1>>Cc1cc(C)n(-c2nc(-c3ccc(Cl)cc3)c(CCC(=O)N3CCN(CC4CCN(C)CC4)CC3)o2)n1 -US20010053851A1,3,C#CC(C)(O)CC.COC(=O)C(CC1CCCC1)c1ccc(I)cc1>>CCC(C)(O)C#Cc1ccc(C(CC2CCCC2)C(=O)OC)cc1 -US05446059,6,COC(=O)c1cc(OC)c(OCc2ccccc2)c(C23CC4CC(CC(C4)C2)C3)c1>>COc1cc(C(=O)O)cc(C23CC4CC(CC(C4)C2)C3)c1OCc1ccccc1 -US07749530B2,1,CN1CCN(c2ccc(N)cc2)CC1.Cc1cc(C(=O)Nc2cccc(Cc3ccc4c(c3)NC(=O)C4=CO)c2)n(C)n1>>Cc1cc(C(=O)Nc2cccc(Cc3ccc4c(c3)NC(=O)C4=CNc3ccc(N4CCN(C)CC4)cc3)c2)n(C)n1 -US20140315881A1,8,Cc1noc(C)c1C(O)COCc1ccccc1>>Cc1noc(C)c1C(=O)COCc1ccccc1 -US06248740B1,1,Cc1cc2nc(C(C)(C)C(=O)OC(C)C)cn2nc1Cl.OCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>Cc1cc2nc(C(C)(C)C(=O)OC(C)C)cn2nc1OCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1 -US07982064B2,7,O=c1ccoc2ccccc12>>O=C1CCOc2ccccc21 -US20090221555A1,1,COCCN1CCc2ccc(N)cc2CC1.CS(=O)(=O)N(CC#N)[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl>>COCCN1CCc2ccc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4N(CC#N)S(C)(=O)=O)n3)cc2CC1 -US20130261125A1,2,Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc(C(=O)O)cc23)ccn1.NC1CCCC(Cc2ccccc2F)(NCc2ccccc2)C1>>Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc(C(=O)NC4CCCC(Cc5ccccc5F)(NCc5ccccc5)C4)cc23)ccn1 -US08133909B2,2,Cc1ccc(NCCc2ccc(C(F)(F)F)nc2)cc1C.O=C(Cl)CBr>>Cc1ccc(N(CCc2ccc(C(F)(F)F)nc2)C(=O)CBr)cc1C -US20090088419A1,6,CCc1nc(CC(C)(C)C)c(CNC(=O)OC(C)(C)C)c(-c2ccc(C)cc2)c1CC(=O)N1CCC[C@H]1C(N)=O>>CCc1nc(CC(C)(C)C)c(CN)c(-c2ccc(C)cc2)c1CC(=O)N1CCC[C@H]1C(N)=O -US06982348B2,2,NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccccc1F.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccccc1F -US08026261B2,6,O=c1cc(C(F)F)n(CC2CC2)cc1OCc1ccccc1>>O=c1cc(C(F)F)n(CC2CC2)cc1O -US06511974B1,1,CCCC[Sn](Cl)(CCCC)CCCC.Cn1cc(Br)cn1>>CCCC[Sn](CCCC)(CCCC)c1cnn(C)c1 -US08772510B2,6,CC(C)(Cc1nc(-c2ccccc2)no1)NC(=O)OC(C)(C)C>>CC(C)(N)Cc1nc(-c2ccccc2)no1 -US20040132786A1,2,NCc1ccccc1C(F)(F)F.O=C(O)c1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1>>O=C(NCc1ccccc1C(F)(F)F)c1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1 -US20150191471A1,2,CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1.Cc1nn(-c2ccc(C(N)=O)c(NCCCOCCOCCOCCOCCOCCCN)c2)c2c1C(=O)CC(C)(C)C2>>Cc1nn(-c2ccc(C(N)=O)c(NCCCOCCOCCOCCOCCOCCCNC(=O)CC[C@H](NC(=O)c3ccc(N(C)Cc4cnc5nc(N)nc(N)c5n4)cc3)C(=O)O)c2)c2c1C(=O)CC(C)(C)C2 -US20070232627A1,7,O=C(Nc1ccc(Sc2ccc(C(=O)Nc3nnc(C(F)(F)F)s3)cc2[N+](=O)[O-])cc1)OCC1c2ccccc2-c2ccccc21>>Nc1cc(C(=O)Nc2nnc(C(F)(F)F)s2)ccc1Sc1ccc(NC(=O)OCC2c3ccccc3-c3ccccc32)cc1 -US08877828B2,1,BrCc1ccc2ccccc2c1.C=CC(=O)O>>C=CC(=O)OCc1ccc2ccccc2c1 -US07101886B2,2,CC(=O)Cl.Nc1ccc(CCN2CCN(c3nsc4ccccc34)CC2)cc1Br>>CC(=O)Nc1ccc(CCN2CCN(c3nsc4ccccc34)CC2)cc1Br -US20080269210A1,2,CC(O)C(=O)O.Nc1ncc(-c2nc(N3CCOCC3)c3sc(C4(O)CCNCC4)cc3n2)cn1>>C[C@H](O)C(=O)N1CCC(O)(c2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)CC1 -US05932571,1,CCOCCN.O=[N+]([O-])c1ccccc1Cl>>CCOCCNc1ccccc1[N+](=O)[O-] -US20150225411A1,2,NC1(C(F)(F)F)CC1.O=C(O)c1cnc(Cl)cn1>>O=C(NC1(C(F)(F)F)CC1)c1cnc(Cl)cn1 -US20100105655A1,1,COc1cc(N2CC3COCC(C2)N3)ccc1N.Clc1ncc(Cl)c(-c2cnc3ccccn23)n1>>COc1cc(N2CC3COCC(C2)N3)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 -US20070197512A1,2,CC(C)c1cccc2c1OC(C(C)C)C(=S)N2CC(=O)O.COC(=O)[C@H](C)O>>COC(=O)[C@H](C)OC(=O)CN1C(=S)[C@H](C(C)C)Oc2c(C(C)C)cccc21 -US20140142119A1,1,COC(=O)c1coc(Cl)n1.Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(N[C@H]4CCC[C@@H](N)C4)n3)c3cc(F)cnc32)cc1>>COC(=O)c1coc(N[C@@H]2CCC[C@H](Nc3nc(-c4cn(S(=O)(=O)c5ccc(C)cc5)c5ncc(F)cc45)ncc3F)C2)n1 -US20080085886A1,1,CCOC(=O)c1oc2c(F)cncc2c1OS(=O)(=O)C(F)(F)F.C[Si](C)(C)c1ccc(N)c(F)c1>>CCOC(=O)c1oc2c(F)cncc2c1Nc1ccc([Si](C)(C)C)cc1F -US08598168B2,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2)cc1NC(=O)c1ccc(N2CC[C@@H](N)C2)cc1>>CC(=O)N[C@@H]1CCN(c2ccc(C(=O)Nc3cc(-c4ccc(F)cc4)ccc3NC(=O)OC(C)(C)C)cc2)C1 -US04648996,1,BrCc1ccccc1Br.CCCCCCCCO>>CCCCCCCCOCc1ccccc1Br -US07910740B2,4,CC(=O)C(Cl)Cc1cccc(Cl)c1.Cc1cn(-c2ccc(NC(N)=S)cc2C#N)cn1>>Cc1cn(-c2ccc(Nc3nc(C)c(Cc4cccc(Cl)c4)s3)cc2C#N)cn1 -US04557867,7,C[C@]12C[C@H](C(F)F)[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC2=O>>C[C@]12C[C@H](C(F)F)[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2O -US07625948B2,1,CNC.COC(=O)Cc1ccc([N+](=O)[O-])c(Br)c1>>COC(=O)Cc1ccc([N+](=O)[O-])c(N(C)C)c1 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3scc(C)c23)cc1Cl.c1c[nH]cn1>>COc1ccc(CNc2nc(-n3ccnc3)nc3scc(C)c23)cc1Cl -US05665718,1,CCCN.O=C1c2ccccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCN12>>CCCNCc1nc(-c2ncn3c2[C@@H]2CCN2C(=O)c2ccccc2-3)no1 -US05151420,1,COc1ccc(C(C)=O)c(O)c1.Nc1ccc(C2=NNC(=O)CC2)cc1>>COc1ccc(C(C)=Nc2ccc(C3=NNC(=O)CC3)cc2)c(O)c1 -US03988373,1,CC1CCCC(C)(C)C1CCC(C)N(C)C.CI>>CC1CCCC(C)(C)C1CCC(C)[N+](C)(C)C -US06369236B1,3,CC(C)(C)NS(=O)(=O)c1ccccc1B(O)O.COCCOc1cc(Br)ccc1Cn1c(-c2ccccc2)nc(Cl)c1C=O>>COCCOc1cc(-c2ccccc2S(=O)(=O)NC(C)(C)C)ccc1Cn1c(-c2ccccc2)nc(Cl)c1C=O -US07148234B2,1,CC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.Nc1ccc(CCO)cc1>>CC(=O)c1ccc(Nc2ccc(CCO)cc2)c([N+](=O)[O-])c1 -US20100216788A1,6,COCCOc1cccc(Oc2ccc(Nc3ncnc4ccn(CCNC(=O)OC(C)(C)C)c34)cc2C)c1>>COCCOc1cccc(Oc2ccc(Nc3ncnc4ccn(CCN)c34)cc2C)c1 -US07030267B2,6,COC(=O)C1(CN)CC12CCCC2>>NCC1(C(=O)O)CC12CCCC2 -US07745641B2,2,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.Cc1nn(C)c(C)c1S(=O)(=O)Cl>>Cc1nn(C)c(C)c1S(=O)(=O)Oc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O -US20020032351A1,7,O=C(O)[C@@H](c1ccc(Cl)cc1)C1CC1>>OC[C@@H](c1ccc(Cl)cc1)C1CC1 -US08637551B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1ccccn1)c1ccccc1-c1noc2cc(Br)ccc12>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccn1)c1ccccc1-c1noc2cc(Br)ccc12 -US08288406B2,6,O=S(=O)(c1ccccc1)n1c2c(c3ccccc31)CCN(CC(O)C1CCC3(CC1)OCCO3)C2>>O=C1CCC(C(O)CN2CCc3c(n(S(=O)(=O)c4ccccc4)c4ccccc34)C2)CC1 -US08664220B2,1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4N)cc3)cc2)CC1.FC(F)(F)c1ccc(-c2cncc(Br)c2)cc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cncc(-c5ccc(C(F)(F)F)cc5)c4)cc3)cc2)CC1 -US20120142672A1,7,C=C(C)c1ccccc1C1CCCn2c(-c3ccc(-c4cnc(C)o4)c(OC)c3)nnc21>>COc1cc(-c2nnc3n2CCCC3c2ccccc2C(C)C)ccc1-c1cnc(C)o1 -US20010006969A1,1,CN(C)N.Cc1csc2c(Cl)nc(Cl)nc12>>Cc1csc2c(NN(C)C)nc(Cl)nc12 -US20080009541A1,2,CCN1C(=O)CC[C@H]1C(=O)OC.NCc1ccc(F)cc1Cl>>CCN1C(=O)CC[C@H]1C(=O)NCc1ccc(F)cc1Cl -US20090023709A1,1,CC(O)CN.O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl>>CC(O)CNc1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccccc1 -US08101644B2,6,COc1ccccc1C1C(C(=O)C(C)(OC)OC)=C(O)C(=O)N1c1ccc(-c2ccon2)cc1>>COc1ccccc1C1C(C(=O)C(C)=O)=C(O)C(=O)N1c1ccc(-c2ccon2)cc1 -US20150005257A1,9,FC(F)(F)c1ccc(COc2ncnc(Cl)c2C2OCCO2)cc1>>FC(F)(F)c1ccc(COc2ncncc2C2OCCO2)cc1 -US07495007B2,3,O=C1Cc2ccc(Br)cc2N1.O=Cc1cccc(Cl)c1>>O=C1Nc2cc(Br)ccc2/C1=C/c1cccc(Cl)c1 -US20030092699A1,2,CCCCN1CCC(CN)CC1.Nc1c(Cl)cc(C(=O)O)c2nc(-c3ccccc3)cn12>>CCCCN1CCC(CNC(=O)c2cc(Cl)c(N)n3cc(-c4ccccc4)nc23)CC1 -US08309581B2,1,N#Cc1ccc(CBr)c(F)c1.Oc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2n1CC1CCCC1>>N#Cc1ccc(COc2cc(Cl)ccc2-c2nc3cc(F)c(F)cc3n2CC2CCCC2)c(F)c1 -US20090036422A1,2,COc1ccc(NCCc2ccc(C(F)(F)F)cc2)cc1OC.COc1ccccc1C(O)C(=O)O>>COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)[C@@H](O)c2ccccc2OC)cc1OC -US04243682,2,CC(=O)Cl.COc1ccc2cc(CCC(C)O)cc(F)c2c1>>COc1ccc2cc(CCC(C)OC(C)=O)cc(F)c2c1 -US20060058356A1,1,CCOC(=O)Cc1nc(Cl)ccc1C(F)(F)F.CN1CCNCC1>>CCOC(=O)Cc1nc(N2CCN(C)CC2)ccc1C(F)(F)F -US04206156,10,C/C=C\P(=O)(OC)OC.O=C1CCC(=O)N1Br>>COP(=O)(/C=C/CBr)OC -US20020120145A1,1,COc1ccc(C=O)cc1.Cn1cncc1C(N)(c1ccc(Cl)nc1)c1ccc2[nH]c(=O)cc(-c3cccc(Cl)c3)c2c1>>COc1ccc(C=NC(c2ccc(Cl)nc2)(c2ccc3[nH]c(=O)cc(-c4cccc(Cl)c4)c3c2)c2cncn2C)cc1 -US20080113966A1,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(CCO)cnc21.CI>>COCCc1cnc2n1C[C@H](c1cccc(F)c1F)CC[C@H]2NC(=O)OC(C)(C)C -US04472406,2,CCOC(CN=C=S)OCC.Cc1ccc2c(N)c(F)ccc2n1>>CCOC(CNC(=S)Nc1c(F)ccc2nc(C)ccc12)OCC -US20090227566A1,1,CC(C)(C)OC(=O)NCCCBr.COC(=O)c1ccc(C(C)(C)C)cc1O>>COC(=O)c1ccc(C(C)(C)C)cc1OCCCNC(=O)OC(C)(C)C -US20150191439A1,1,COc1ccccc1COc1ccc(C=O)cc1.NC12CC3CC(CC(C3)C1)C2>>COc1ccccc1COc1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1 -US07691882B2,1,Brc1ccc(Br)nc1.Oc1ccccc1>>Brc1ccc(Oc2ccccc2)nc1 -US20100324130A1,1,O=[N+]([O-])c1cc(F)ccc1F.Oc1ccccc1>>O=[N+]([O-])c1cc(F)ccc1Oc1ccccc1 -US20060258659A1,1,CCCCCN.Ic1cccs1>>CCCCCNc1cccs1 -US08729061B2,2,CC(C)[C@H](N)C(=O)C(=O)NC1CC1.O=C(O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1C(=O)C1(c2ncc(Cl)cc2F)CC1>>CC(C)[C@H](NC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1C(=O)C1(c2ncc(Cl)cc2F)CC1)C(=O)C(=O)NC1CC1 -US07067534B1,1,CCC(=O)Nc1cccc(C2CCNCC2)c1.O=C(CCCCCl)c1ccccc1F>>CCC(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccccc3F)CC2)c1 -US20130197052A1,2,NCCc1c[nH]c2ccc(O)cc12.O=C(O)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1>>O=C(NCCc1c[nH]c2ccc(O)cc12)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1 -US04851413,3,CN(C)C=O.COc1c(C)c(Br)c(OC)c2ccccc12>>COc1c(C)c(C=O)c(OC)c2ccccc12 -US20050192347A1,2,CC(CO)(CCCCCN)c1ccccc1.O=C=NCCCCc1ccccc1>>CC(CO)(CCCCCNC(=O)NCCCCc1ccccc1)c1ccccc1 -US20090105305A1,2,CS(=O)(=O)Cl.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1N>>Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(C)(=O)=O -US20090048269A1,1,Cc1cc(O)c(-c2ccccn2)nc1C.Clc1ccnc(Cl)c1>>Cc1cc(Oc2ccnc(Cl)c2)c(-c2ccccn2)nc1C -US20090093518A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(Cl)nccc3c2)CC1.OCc1ccccc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(OCc4ccccc4)nccc3c2)CC1 -US20150274704A1,1,O=C(CBr)C1(C(=O)NCc2ccccc2)CCCC1>>O=C1CN(Cc2ccccc2)C(=O)C12CCCC2 -US05977101,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CC1Nc2ccc(C(=O)O)cc2CN(C)C1=O>>COC(=O)CC1C(=O)N(C)Cc2cc(C(=O)O)ccc2N1C(=O)OC(C)(C)C -US08173813B2,1,CN(C)CCCl.O=C1CCc2cc([N+](=O)[O-])ccc2N1>>CN(C)CCN1C(=O)CCc2cc([N+](=O)[O-])ccc21 -US09078330B2,3,C#C[Si](C)(C)C.Ic1cccc(-c2ccccn2)c1>>C[Si](C)(C)C#Cc1cccc(-c2ccccn2)c1 -US20110212956A1,2,CC(=O)OC(C)=O.Cc1ccc(CCN)cc1>>CC(=O)NCCc1ccc(C)cc1 -US05643932,1,CCCCCCCCCBr.CCOc1ccc(-c2nc(-c3ccc(OCOC)c(C(=O)O)c3)cs2)cc1OCC>>CCCCCCCCCOC(=O)c1cc(-c2csc(-c3ccc(OCC)c(OCC)c3)n2)ccc1OCOC -US06809199B2,6,COc1cc(-c2cc(F)ccc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)CC2>>O=C1CCc2c(-c3cc(F)ccc3Cl)cc(O)cc2N1c1c(Cl)cccc1Cl -US06368608B1,7,COC(=O)c1ccc(C#CC(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1O>>COC(=O)c1ccc(C#CC(O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1O -US04105790,3,CCN(CC)C(=O)COc1ccccc1.O=C(Cl)CCl>>CCN(CC)C(=O)COc1ccc(C(=O)CCl)cc1 -US06458784B1,6,COC(=O)CC1Nc2ccc(C(=O)Nc3ccc(N)nc3)cc2CN(CCc2ccccc2)C1=O>>Nc1ccc(NC(=O)c2ccc3c(c2)CN(CCc2ccccc2)C(=O)C(CC(=O)O)N3)cn1 -US20070099901A1,9,CC(=O)CCCn1c(C)nc2c(N)nc3ccccc3c21.NO>>CC(CCCn1c(C)nc2c(N)nc3ccccc3c21)=NO -US20040034028A1,1,O=C(NC1CCNCC1)c1ccccc1-c1ccccc1.O=Cc1ccc2ccccc2n1>>O=C(NC1CCN(Cc2ccc3ccccc3n2)CC1)c1ccccc1-c1ccccc1 -US20060148858A1,3,CCCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1/C=C/C(=O)OCC -US20060148858A1,8,CCC(CC)c1nn(Cc2ccccc2)cc1CO>>CCC(CC)c1nn(Cc2ccccc2)cc1C=O -US08362236B2,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(C)cc1OC.Nc1nc(Cl)cc(Cl)n1>>COC(=O)c1cc(-c2cc(Cl)nc(N)n2)c(C)cc1OC -US20060035938A1,2,COc1ccc(CN)cc1.Cc1ccc(C(=O)O)c(=O)n1-c1ccccc1>>COc1ccc(CNC(=O)c2ccc(C)n(-c3ccccc3)c2=O)cc1 -US07582773B2,4,CCCCCc1c(-c2ccccc2)n(Cc2ccccc2)c2ccc(-c3ccc(OCC#N)cc3)cc12.[N-]=[N+]=[N-]>>CCCCCc1c(-c2ccccc2)n(Cc2ccccc2)c2ccc(-c3ccc(OCc4nnn[nH]4)cc3)cc12 -US20100137313A1,6,COC(=O)c1cc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)cnc1OC(C)c1ccncc1>>CC(Oc1ncc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)cc1C(=O)O)c1ccncc1 -US09040538B2,1,Cc1cc(N)nc(S)n1.Clc1cncc(Cl)c1CBr>>Cc1cc(N)nc(SCc2c(Cl)cncc2Cl)n1 -US05710180,2,COc1ccc(C(C#N)CN)cc1OC1CCCC1.C[Si](C)(C)N=C=O>>COc1ccc(C(C#N)CNC(N)=O)cc1OC1CCCC1 -US05859007,6,COc1ccc(N(C(=O)CN2C(=O)C(Cc3nn(C(=O)OC(C)(C)C)c4ccccc34)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1>>COc1ccc(N(C(=O)CN2C(=O)C(Cc3n[nH]c4ccccc34)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1 -US08497368B2,1,CI.Fc1cc2[nH]ncc2cc1Br>>Cn1ncc2cc(Br)c(F)cc21 -US07767691B2,1,N#CC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2.N#CCCCBr>>N#CCCC[N+]12CCC(C(C#N)(c3ccccc3)c3ccccc3)(CC1)C2 -US20050065135A1,1,C=C[C@@]12CCc3cc(O)ccc3[C@H]1[C@@H](CCCCCCCl)C[C@@]1(C)[C@H]2CC[C@@H]1O.CNC>>C=C[C@@]12CCc3cc(O)ccc3[C@H]1[C@@H](CCCCCCN(C)C)C[C@@]1(C)[C@H]2CC[C@@H]1O -US06943168B2,10,COc1cc(C(=O)N2CCN(C(=O)CCCC=C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc(OC)c1OC.O>>COc1cc(C(=O)N2CCN(C(=O)CCCC(O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc(OC)c1OC -US06730687B1,3,COc1ccc(C=O)cc1.O=C1CSC(=O)N1>>COc1ccc(C=C2SC(=O)NC2=O)cc1 -US20060172999A1,3,C=CCC[Mg+].C[C@@H](O[C@H]1OCC[C@@H](C=O)[C@@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C=CCCC(O)[C@@H]1CCO[C@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]1c1ccccc1 -US08309563B2,1,Clc1ncnc2ccc(Br)cc12.Nc1ccc(OCc2cccc(F)c2)c(Cl)c1>>Fc1cccc(COc2ccc(Nc3ncnc4ccc(Br)cc34)cc2Cl)c1 -US08269008B2,2,CCOC(=O)c1ncc2c(-c3ccccc3)noc2c1O.NCC(=O)O>>O=C(O)CNC(=O)c1ncc2c(-c3ccccc3)noc2c1O -US20100076014A1,1,Cc1cc2[nH]ncc2cc1O.Fc1ccc(I)cc1>>Cc1cc2c(cnn2-c2ccc(F)cc2)cc1O -US20090163489A1,3,CC(=O)Nc1nc2cc(Br)ccc2[nH]1.O=S(=O)(Nc1cc(Br)cnc1Cl)c1ccc(F)cc1>>CC(=O)Nc1nc2cc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4)c3)ccc2[nH]1 -US20060189544A1,6,CCOC(=O)CC(NC(=O)CNC(=O)c1cccc(N)c1)c1ccccc1>>Nc1cccc(C(=O)NCC(=O)NC(CC(=O)O)c2ccccc2)c1 -US20050014818A1,2,CS(=O)(=O)Cl.OC[C@H]1CCc2ccccc2O1>>CS(=O)(=O)OC[C@H]1CCc2ccccc2O1 -US20120184587A1,6,COc1c(Cl)cc(C(=O)N2CS(=O)(=O)c3ccccc32)cc1Cl>>O=C(c1cc(Cl)c(O)c(Cl)c1)N1CS(=O)(=O)c2ccccc21 -US20090221555A1,2,CCOC(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2)CCN(CCOC)CC3)ncc1Cl.COCCCN>>COCCCNC(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2)CCN(CCOC)CC3)ncc1Cl -US05679699,1,CNCc1ccccc1.ClCCCBr>>CN(CCCCl)Cc1ccccc1 -US20070037834A1,6,CCN1CCO[C@H](CN2CCN(C(=O)OC(C)(C)C)CC2)C1>>CCN1CCO[C@H](CN2CCNCC2)C1 -US20090275606A1,2,C=CCC1(S(=O)(=O)Cl)CC1.Cc1c(=O)n2c(c3[nH]c(=O)n(-c4ccc(Br)cc4F)c13)CCC2>>C=CCC1(S(=O)(=O)n2c(=O)n(-c3ccc(Br)cc3F)c3c(C)c(=O)n4c(c32)CCC4)CC1 -US04810792,1,C#CC1(O)CCN(C)CC1.O=[N+]([O-])c1ccccc1F>>C#CC1(Oc2ccccc2[N+](=O)[O-])CCN(C)CC1 -US20080200461A1,2,CCN(CC)CCCCNCc1cc(C)cc(C)c1.O=C(O)c1ccc2ccccc2c1>>CCN(CC)CCCCN(Cc1cc(C)cc(C)c1)C(=O)c1ccc2ccccc2c1 -US07825256B2,3,CON(C)C(=O)c1cc(C)nc(-n2ccnc2)n1.C[Mg+]>>CC(=O)c1cc(C)nc(-n2ccnc2)n1 -US20090029964A1,1,CC(C)(C)C(=O)OCI.C[C@@H](O)[C@H]1C(=O)N2C(C(=O)[O-])=C(c3ccc(N4CCOC4=O)cc3)C[C@H]12>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCOC(=O)C(C)(C)C)=C(c3ccc(N4CCOC4=O)cc3)C[C@H]12 -US20090221555A1,1,CN(C)C(=O)CCl.COc1cc2c(cc1[N+](=O)[O-])CCNCC2>>COc1cc2c(cc1[N+](=O)[O-])CCN(CC(=O)N(C)C)CC2 -US20090093518A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.COc1ccc(Cn2ccc3cc(F)c(Br)cc3c2=O)cc1>>COc1ccc(Cn2ccc3cc(OC4CCN(C(=O)OC(C)(C)C)CC4)c(Br)cc3c2=O)cc1 -US20140309192A1,2,Nc1ccc(Cl)cc1N1CCN(CCC(F)(F)F)CC1.O=C(O)c1ccc(-n2cccc2)cc1>>O=C(Nc1ccc(Cl)cc1N1CCN(CCC(F)(F)F)CC1)c1ccc(-n2cccc2)cc1 -US20040249151A1,1,Brc1ccncc1.CNCC1CCN(C(=O)OC(C)(C)C)CC1>>CN(CC1CCN(C(=O)OC(C)(C)C)CC1)c1ccncc1 -US03939267,1,CC(=O)Nc1ccc(O)cc1.NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl>>CC(=O)Nc1ccc(Oc2c([N+](=O)[O-])cc(C(=O)O)cc2S(N)(=O)=O)cc1 -US20120208819A1,1,N#Cc1cnc(F)c(-c2ncco2)c1.NCc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1>>N#Cc1cnc(NCc2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4ncnc(N)c34)cc2)c(-c2ncco2)c1 -US20140303137A1,1,Nc1ncns1.O=C(Nc1ccc(Sc2nc(Cl)cc(Cl)n2)cc1)c1ccccc1Cl>>O=C(Nc1ccc(Sc2nc(Cl)cc(Nc3ncns3)n2)cc1)c1ccccc1Cl -US05206240,1,BrCCc1ccc2nonc2c1.CS(=O)(=O)Nc1ccc2c(c1)C(=O)CC1(CCNCC1)O2>>CS(=O)(=O)Nc1ccc2c(c1)C(=O)CC1(CCN(CCc3ccc4nonc4c3)CC1)O2 -US20090215759A1,1,COc1cc(N)ccc1-n1cnc(C)c1.Cc1cc(Cl)nc(N2CCCC2)n1>>COc1cc(Nc2cc(C)nc(N3CCCC3)n2)ccc1-n1cnc(C)c1 -US04547514,2,CCN(CC)CCCN.O=C(Cl)N1CCC(Oc2cccc(Cl)c2)C1>>CCN(CC)CCCNC(=O)N1CCC(Oc2cccc(Cl)c2)C1 -US07560558B2,3,CCOc1cccc(B(O)O)c1.COc1cc2nccc(Oc3ccc(C)nc3I)c2cc1OC>>CCOc1cccc(-c2nc(C)ccc2Oc2ccnc3cc(OC)c(OC)cc23)c1 -US20090163489A1,2,CC(=O)OC(C)=O.Nc1nc2ccc(Br)cc2n1-c1ccccn1>>CC(=O)Nc1nc2ccc(Br)cc2n1-c1ccccn1 -US20140288123A1,2,CC(Oc1ncccn1)c1ccc(C(=O)O)cc1.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(C(C)Oc3ncccn3)cc2)c(O)n1 -US08318949B2,1,C=CCCBr.CCOC(=O)c1sc(N2CCNC2=O)nc1C>>C=CCCN1CCN(c2nc(C)c(C(=O)OCC)s2)C1=O -US20020193367A1,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1.CN(c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl)C1CC1>>CN(c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3nncc3COC3CCCCO3)c2)cc1Cl)C1CC1 -US05372800,2,CCCCCCCCCCCC(=O)Cl.Oc1c(I)cc(I)cc1I>>CCCCCCCCCCCC(=O)Oc1c(I)cc(I)cc1I -US08304419B2,2,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1.O=C(O)c1csnn1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3csnn3)c2F)c1 -US20120115862A1,6,COc1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3N)cc1CC2>>Nc1cc(F)ccc1Nc1ccc2c(c1)CCc1ccc(O)cc1C2=O -US07060700B2,2,Cc1ccc(NC(=O)c2cccc(N3CCOCC3)c2)cc1N.O=C(Cl)c1cccs1>>Cc1ccc(NC(=O)c2cccc(N3CCOCC3)c2)cc1NC(=O)c1cccs1 -US20150284411A1,9,NO.O=C1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@H]12>>ON=C1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@H]12 -US04610818,2,CC(C)C[C@H](N)C(=O)NCC(N)=O.O=C(O)c1ccc[nH]1>>CC(C)C[C@H](NC(=O)c1ccc[nH]1)C(=O)NCC(N)=O -US20130267499A1,9,CCOC(=O)C1CCN(Cc2ccccc2)c2c(cnn2Cc2ccc(OC)cc2)C1=O>>COc1ccc(Cn2ncc3c2N(Cc2ccccc2)CCCC3=O)cc1 -US20060135447A1,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.Clc1ccc(Cl)nn1>>Nc1ccc(-c2ccc(Cl)nn2)cc1 -US20040044008A1,6,CC(C)(C)OC(=O)Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1>>CC(C)(C)OC(=O)Nc1ccc(N2CCNCC2)cc1 -US20010051631A1,3,C=O.CCc1cn2c(CNCCCCCNS(=O)(=O)C(F)(F)F)cccc2n1>>CCc1nc2cccc3n2c1CN(CCCCCNS(=O)(=O)C(F)(F)F)C3 -US04130650,1,C1COCCN1.ClCCOc1ccccc1C=Cc1ccccn1>>C(=Cc1ccccc1OCCN1CCOCC1)c1ccccn1 -US20120040966A1,2,CC(=O)CC(=O)Cl.O=C1CCNc2ccccc21>>CC(=O)CC(=O)N1CCC(=O)c2ccccc21 -US20110009402A1,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O.Cc1c(Br)cc(=O)n(C)c1C>>Cc1c(-c2ccc([C@H](C)N3CC[C@](CC(C)(C)O)(c4ccccc4)OC3=O)cc2)cc(=O)n(C)c1C -US06825170B2,7,O=C/C=C/c1ccc(-n2cccn2)nc1>>OC/C=C/c1ccc(-n2cccn2)nc1 -US08114894B2,1,CC(C)I.c1ccc2[nH]ccc2c1>>CC(C)n1ccc2ccccc21 -US20150141427A1,3,O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(Br)c1F.OB(O)c1cncnc1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(-c2cncnc2)c1F -US20070219235A1,1,Brc1ccccc1C1CCCCC1.CC(C)(C)OC(N)=O>>CC(C)(C)OC(=O)Nc1ccccc1C1CCCCC1 -US20110015232A1,1,COc1ccc([C@@H](C)N2CCC[C@H]2c2ccnc(Br)c2)cc1.c1ccc2c(c1)CCN2>>COc1ccc([C@@H](C)N2CCC[C@H]2c2ccnc(N3CCc4ccccc43)c2)cc1 -US06967198B2,2,Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O.O=C(O)c1cccc(C(F)(F)F)c1>>O=C(Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)c1cccc(C(F)(F)F)c1 -US06399773B1,2,Nc1ccccc1Br.O=C(Cl)CBr>>O=C(CBr)Nc1ccccc1Br -US20110212956A1,2,CC1NCCc2cc(Cl)c(Cl)cc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2cc(Cl)c(Cl)cc2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US06740670B2,1,CS(=O)(=O)OCc1cc(C=O)ccc1OCc1ccccc1.c1ccc(N2CCNCC2)cc1>>O=Cc1ccc(OCc2ccccc2)c(CN2CCN(c3ccccc3)CC2)c1 -US06432950B1,1,O=[N+]([O-])c1cc2c(NCc3ccc4c(c3)OCO4)nc(Cl)nc2s1.c1cn[nH]c1>>O=[N+]([O-])c1cc2c(NCc3ccc4c(c3)OCO4)nc(-n3cccn3)nc2s1 -US05807857,6,CCOC(=O)CCc1c[nH]c2cnc(-n3cnnc3)cc12>>O=C(O)CCc1c[nH]c2cnc(-n3cnnc3)cc12 -US20050124605A1,1,CI.Cc1cc(C)nc(O[C@@H]2C(=O)N3CC(=O)Nc4ccccc4[C@@]23c2cccc(C(F)(F)F)c2)n1>>Cc1cc(C)nc(O[C@@H]2C(=O)N3CC(=O)N(C)c4ccccc4[C@@]23c2cccc(C(F)(F)F)c2)n1 -US20090286777A1,7,COC(=O)/C=C/[C@H]1[C@H](c2ccc(F)cc2)[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1C(=O)OC(C)(C)C>>COC(=O)CC[C@H]1[C@H](c2ccc(F)cc2)[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1C(=O)OC(C)(C)C -US20140364432A1,7,COC(=O)c1ncccc1C>>COC(=O)[C@H]1NCCC[C@H]1C -US20100184786A1,1,C[S-].N#Cc1ccc(F)cc1F>>CSc1cc(F)ccc1C#N -US06071934,7,CSc1ccc(/C=C2/C(C)=C(CC(=O)O)c3cc(F)ccc32)cc1>>CSc1ccc(/C=C2/C(C)=C(CCO)c3cc(F)ccc32)cc1 -US20140155367A1,1,N#Cc1ccc(Br)nc1.NC1COC1>>N#Cc1ccc(NC2COC2)nc1 -US20120225847A1,2,CC(C)(C)OC(=O)NCCCCCO.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)NCCCCCOC(=O)Oc1ccc([N+](=O)[O-])cc1 -US20150210697A1,1,COc1ccc(CN(c2nc(Cl)nn3c(C#N)cnc23)C2CC2)cc1.COc1ccc(CN2CCOC[C@H]2COc2cc(C#N)cc(N)c2Cl)c(OC)c1>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(OC[C@@H]4COCCN4Cc4ccc(OC)cc4OC)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1 -US08048909B2,6,CN(Cc1cc(-c2ccccc2)n(S(=O)(=O)c2ccccc2C(=O)O)c1)C(=O)OC(C)(C)C>>CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2ccccc2C(=O)O)c1 -US07414061B2,1,Cc1onc(-c2ccc(F)cc2)c1-c1c[nH]cn1.Clc1ncccn1>>Cc1onc(-c2ccc(F)cc2)c1-c1cn(-c2ncccn2)cn1 -US06982278B2,1,C=CCc1ccccc1O.CCOC(=O)CBr>>C=CCc1ccccc1OCC(=O)OCC -US05656634,1,CCCCCCCC(Br)C(=O)OCC.CCCc1ccc(S)cc1>>CCCCCCCC(Sc1ccc(CCC)cc1)C(=O)OCC -US20100234395A1,6,COc1ccc(-c2nc(C3(COC(C)=O)CCN(C(=O)N(C)O)CC3)oc2-c2ccc(OC)cc2)cc1>>COc1ccc(-c2nc(C3(CO)CCN(C(=O)N(C)O)CC3)oc2-c2ccc(OC)cc2)cc1 -US06984649B1,6,CC(C)(C)OC(=O)N1CCCC(c2cc(-c3c(O)cccc3OCc3ccccc3)nc(N)c2C#N)C1>>N#Cc1c(C2CCCNC2)cc(-c2c(O)cccc2OCc2ccccc2)nc1N -US20090239864A1,2,CN(C)C(=O)Cl.Cn1c(N2CCO[C@@H](c3ccc(N)cc3)C2)nc(-c2ccncc2F)cc1=O>>CN(C)C(=O)Nc1ccc([C@H]2CN(c3nc(-c4ccncc4F)cc(=O)n3C)CCO2)cc1 -US20100216767A1,6,C[C@@H](COc1cc(Nc2ncc3cc(C#C[Si](C)(C)C)ccc3n2)cc(-c2cnn(C)c2)c1)NC(=O)OC(C)(C)C>>C[C@H](N)COc1cc(Nc2ncc3cc(C#C[Si](C)(C)C)ccc3n2)cc(-c2cnn(C)c2)c1 -US20110319378A1,6,CCN(CC)N1C(=O)[C@@](C)(CC(=O)OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CCN(CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US08269002B2,1,CO.Fc1c(Cl)cccc1CSc1nc(Cl)cc(Cl)n1>>COc1cc(Cl)nc(SCc2cccc(Cl)c2F)n1 -US20100249163A1,1,CCI.COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(F)c(F)c2)C2CC2)cc(OCCOC)c1>>CCO[C@]1(c2ccc(F)c(F)c2)CCN(C(=O)OC(C)(C)C)C[C@@H]1C(=O)N(Cc1cc(CCCOC)cc(OCCOC)c1)C1CC1 -US20050282812A1,2,CCC1CN(C(C(=O)OC)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc2N1.CCOC(=O)Cl>>CCOC(=O)N1c2ccccc2N(C(C(=O)OC)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC -US20020160996A1,2,Cc1oc2c(C)c(C)c(N)c(C)c2c1-c1ccc(C(C)C)cc1.O=C(Cl)c1ccc(F)cc1>>Cc1oc2c(C)c(C)c(NC(=O)c3ccc(F)cc3)c(C)c2c1-c1ccc(C(C)C)cc1 -US08946260B2,3,C=CC(=O)OCC.FC(F)(F)c1ccc(Br)cc1Cl>>CCOC(=O)C=Cc1ccc(C(F)(F)F)c(Cl)c1 -US04150137,2,CC(C)Cc1ccc(C(C)C(=O)O)cc1.Cc1ccc(CO)cc1>>Cc1ccc(COC(=O)C(C)c2ccc(CC(C)C)cc2)cc1 -US20090312327A1,7,O=[N+]([O-])C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1>>NC1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1 -US20060223850A1,3,CC(=O)c1ccc(B(O)O)cc1.CC(C)(c1cc(-c2cccc(-c3ccccc3Br)c2)c2ncccc2c1)S(C)(=O)=O>>CC(=O)c1ccc(-c2ccccc2-c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)cc1 -US20080090794A1,1,CC(C)(C)[S@@](N)=O.N#Cc1cccc(C=O)c1>>CC(C)(C)[S@](=O)N=Cc1cccc(C#N)c1 -US20140249126A1,7,CCn1cc(C(=O)O)c(=O)c2c(Cl)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21>>CCn1cc(CO)c(=O)c2c(Cl)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21 -US20060135773A1,3,CCc1cccc(B(O)O)c1.COc1ccccc1S(=O)(=O)NCc1ccccc1Br>>CCc1cccc(-c2ccccc2CNS(=O)(=O)c2ccccc2OC)c1 -US20100216846A1,1,CCC(O)Cn1nc(Nc2cccc(Cl)c2)nc1-c1ccnc(Cl)c1.CCN>>CCNc1cc(-c2nc(Nc3cccc(Cl)c3)nn2C[C@@H](O)CC)ccn1 -US20070105919A1,6,CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2nc(-c3ccco3)c(C(=O)C3CCOCC3)s2)CC1>>O=C(CN1CCNCC1)Nc1nc(-c2ccco2)c(C(=O)C2CCOCC2)s1 -US20030195176A1,1,CCC(C)(O)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C.CC[Si](CC)(CC)OC(C)(C)C/C=C\Br>>CCC(C)(O/C=C\CC(C)(C)O[Si](CC)(CC)CC)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C -US07888352B2,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1c(C=O)sc2c(N3CCOCC3)nc(Cl)nc12>>Cc1c(CN2CCN(C(=O)OC(C)(C)C)CC2)sc2c(N3CCOCC3)nc(Cl)nc12 -US06331538B1,1,C1CCNC1.Cc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(Cl)nc32)cc1>>Cc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(N4CCCC4)nc32)cc1 -US05057524,2,CNC.O=C(Cl)CCCCCl>>CN(C)C(=O)CCCCCl -US20130274260A1,6,CCOC(=O)c1cccc(Oc2cccc(OC)c2)c1>>COc1cccc(Oc2cccc(C(=O)O)c2)c1 -US20080194647A1,6,C[Si](C)(C)C#Cc1ccc(F)c(F)c1>>C#Cc1ccc(F)c(F)c1 -US20100069381A1,2,C1CCNC1.Cc1nnc(-c2ccc3occ(-c4ccc(C(=O)O)c(F)c4)c3c2)o1>>Cc1nnc(-c2ccc3occ(-c4ccc(C(=O)N5CCCC5)c(F)c4)c3c2)o1 -US20030199550A1,1,CN.CN(C[C@@H]1CC[C@@H](COC/C=C/CBr)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1>>CNC/C=C/COC[C@@H]1CC[C@@H](CN(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1 -US07229987B2,2,COC(=O)c1ccc(C(=O)[O-])cc1.NNC(=O)CSCCOc1ccc(Cl)cc1Cl>>COC(=O)c1ccc(C(=O)NNC(=O)CSCCOc2ccc(Cl)cc2Cl)cc1 -US20090054428A1,7,Cc1nc(Cl)c(C(=O)O)cc1N>>Cc1nc(Cl)c(CO)cc1N -US05556977,6,CCOC(=O)CCCCCOc1ccc(N(C(=O)OC(C)(C)C)c2ccncc2)cc1>>CCOC(=O)CCCCCOc1ccc(Nc2ccncc2)cc1 -US20060025433A1,1,CC(C)(C)OC(=O)NCc1cccc(CN)c1.N#CSc1nc(Cl)ncc1[N+](=O)[O-]>>CC(C)(C)OC(=O)NCc1cccc(CNc2ncc([N+](=O)[O-])c(SC#N)n2)c1 -US04372964,1,CI.COc1ccc(-c2nc[nH]c2-c2ccc(OC)cc2)cc1>>COc1ccc(-c2ncn(C)c2-c2ccc(OC)cc2)cc1 -US03951978,1,C1COCCN1.O=C(c1ccc(F)cc1)C(Br)CCCl>>O=C(c1ccc(F)cc1)C(CCCl)N1CCOCC1 -US20150218143A1,1,CCOC(=O)c1ccc(S(=O)(=O)N(Cc2ccc3c(Cl)c[nH]c3c2)c2ncc3ccccc3c2C)cc1.CI>>CCOC(=O)c1ccc(S(=O)(=O)N(Cc2ccc3c(Cl)cn(C)c3c2)c2ncc3ccccc3c2C)cc1 -US20080020116A1,7,CCCC[C@H](O)CC(=O)OC>>CCCC[C@H](O)CCO -US20130172328A1,6,CCn1c(=O)n(-c2ccc(OCc3ccccc3)cc2)c2ncc(Cl)cc21>>CCn1c(=O)n(-c2ccc(O)cc2)c2ncc(Cl)cc21 -US20060100218A1,2,COc1ccc(-c2c[nH]c3ncccc23)cc1OC.S=C=Nc1ccccc1>>COc1ccc(-c2cn(C(=S)Nc3ccccc3)c3ncccc23)cc1OC -US04125614,7,CN(C)S(=O)(=O)c1cc(C(=O)CBr)ccc1Cl>>CN(C)S(=O)(=O)c1cc(C(O)CBr)ccc1Cl -US20150175601A1,1,C=CC(=O)Nc1cccc(-c2cccc3cnc(Cl)nc23)c1.CN1CCN(c2ccc(N)c(F)c2F)CC1>>C=CC(=O)Nc1cccc(-c2cccc3cnc(Nc4ccc(N5CCN(C)CC5)c(F)c4F)nc23)c1 -US20020022633A1,1,BrCc1ccccc1.O=c1ccc2ccc(O)cc2[nH]1>>O=c1ccc2ccc(OCc3ccccc3)cc2[nH]1 -US06933311B2,7,N#Cc1ccc(N2CCOCC2)cc1>>NCc1ccc(N2CCOCC2)cc1 -US20150246048A1,3,CN(c1ncnc2[nH]ccc12)[C@H]1C[C@@H](NS(=O)(=O)c2cccc(C=O)c2)C1.C[Mg+]>>CC(O)c1cccc(S(=O)(=O)N[C@@H]2C[C@H](N(C)c3ncnc4[nH]ccc34)C2)c1 -US08304419B2,2,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1.[N-]=[N+]=Nc1nc(Cl)c(C(=O)O)[nH]1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]c(N=[N+]=[N-])nc3Cl)c2F)c1 -US05112920,2,CC(=O)OC(C)=O.CNCCN(C)C>>CC(=O)N(C)CCN(C)C -US20010051642A1,7,COc1ccc2c(c1C#Cc1ccccc1)CCCC2=O>>COc1ccc2c(c1CCc1ccccc1)CCCC2=O -US20030036551A1,6,O=C(Nc1cc(Cl)c2c(c1)CN(C(=O)C(F)(F)F)CC2)c1ccc(Cl)s1>>O=C(Nc1cc(Cl)c2c(c1)CNCC2)c1ccc(Cl)s1 -US20050176701A1,1,CCc1cc(Br)cc(Cl)c1O.CI>>CCc1cc(Br)cc(Cl)c1OC -US05358938,1,CCCI.COc1cc(C=O)cc([N+](=O)[O-])c1O>>CCCOc1c(OC)cc(C=O)cc1[N+](=O)[O-] -US06949542B2,2,CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1N.CC(C)Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)ccn1>>CC(C)Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(OCC(F)(F)F)cc3NC(=O)OC(C)(C)C)c2)ccn1 -US20090264445A1,6,COC(=O)[C@H](CC1CCCCC1)N1CC(Oc2ccccc2SC)=CC1=O>>CSc1ccccc1OC1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)O)C1 -US20080096861A1,1,NCc1nc2ccccc2[nH]1.O=C1CCCc2cccnc21>>c1cnc2c(c1)CCCC2NCc1nc2ccccc2[nH]1 -US08093265B2,2,Cc1ccc2c(=O)n(CCN(C)C(=O)OC(C)(C)C)ccc2c1N.O=C(O)Cc1ccc(C(F)(F)F)c(F)c1>>Cc1ccc2c(=O)n(CCN(C)C(=O)OC(C)(C)C)ccc2c1NC(=O)Cc1ccc(C(F)(F)F)c(F)c1 -US04720585,8,COc1ccc(CSC(CO)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1>>COc1ccc(CSC(C=O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1 -US20060069110A1,1,CN(c1ccnc(-c2ccccc2)n1)c1nc(Cl)ncc1F.NCCc1cccnc1>>CN(c1ccnc(-c2ccccc2)n1)c1nc(NCCc2cccnc2)ncc1F -US20130011345A1,2,C#CC#CCC/C=C\C(=O)O.CCC(C)CN>>C#CC#CCC/C=C\C(=O)NCC(C)CC -US07863441B2,7,CC(=O)OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1>>OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1 -US20050272778A1,2,CCOP(=O)(OCC)C(F)(F)c1ccc(CC(=O)O)cc1.NC(=O)[C@H](Cc1ccc(C2=CC(=O)NS2(=O)=O)cc1)NC(=O)[C@@H](N)Cc1ccccc1>>CCOP(=O)(OCC)C(F)(F)c1ccc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(C3=CC(=O)NS3(=O)=O)cc2)C(N)=O)cc1 -US05698720,6,COC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C=C(C#N)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@]12CCC(C#N)=CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)O)CC[C@@H]12 -US05332739,1,Cn1c(Cl)cc(=O)[nH]c1=O.c1ccc(OCCCN2CCNCC2)cc1>>Cn1c(N2CCN(CCCOc3ccccc3)CC2)cc(=O)[nH]c1=O -US07816354B2,9,[N-]=[N+]=NCC(O)c1cccc(Br)c1>>NCC(O)c1cccc(Br)c1 -US04454158,6,O=C1c2ccccc2C(=O)N1C/C(=C\Cl)c1ccccc1>>NC/C(=C\Cl)c1ccccc1 -US05578612,5,CC(C)(C)NS(=O)(=O)Cc1cc(Br)c(N)c(Br)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)NS(=O)(=O)Cc1cc(Br)c(NC(=O)C(F)(F)F)c(Br)c1 -US05123951,2,CCOC(=O)C1(C(=O)O)CC1.Nc1ccccc1>>CCOC(=O)C1(C(=O)Nc2ccccc2)CC1 -US20080269193A1,6,CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@H]4CCCC[C@@H]4OC(=O)CNC(=O)OC(C)(C)C)c3)c2C1>>CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@H]4CCCC[C@@H]4OC(=O)CN)c3)c2C1 -US08722683B2,1,CC(C)(O)C(=O)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1.CI>>COC(C)(C)C(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3cccc4c3OCO4)CC2)CC1 -US20090105259A1,2,CC(C)(C)OC(=O)NCCCCN.CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)O>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCCCNC(=O)OC(C)(C)C -US05587383,2,CS(=O)(=O)Cl.OCCOc1ccccc1>>CS(=O)(=O)OCCOc1ccccc1 -US20070010402A1,3,CCCC[Sn](CCCC)(CCCC)CCCC.Cc1cc2c(-c3cccc(OC(F)(F)F)c3)nc(Cl)nc2s1>>CCCCc1nc(-c2cccc(OC(F)(F)F)c2)c2cc(C)sc2n1 -US07022259B2,2,C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccccc12.CCCCCCOc1ccc(C(=O)O)cc1>>C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@H](OC(=O)c1ccc(OCCCCCC)cc1)c1ccnc2ccccc12 -US07199244B2,3,CC(C)(C)[Si](C)(C)OC1CCOc2ccccc21.CN(C)C=O>>CC(C)(C)[Si](C)(C)OC1CCOc2c(C=O)cccc21 -US06528528B2,2,COc1ccc(C(=O)Nc2ccccc2)cc1N.Cc1ccccc1N=C=S>>COc1ccc(C(=O)Nc2ccccc2)cc1NC(=S)Nc1ccccc1C -US07365088B2,1,CC(C)(C)OC(=O)NC1CCNCC1.CC(C)=O>>CC(C)N1CCC(NC(=O)OC(C)(C)C)CC1 -US20060106037A1,2,CCO.COc1cc(CC(=O)O)ccc1OC(F)F>>CCOC(=O)Cc1ccc(OC(F)F)c(OC)c1 -US20110009619A1,2,CC(CCO)C(C(=O)NNC(=O)OC(C)(C)C)c1ccc(F)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCC(C)C(C(=O)NNC(=O)OC(C)(C)C)c2ccc(F)cc2)cc1 -US20120010207A1,1,Cc1cc(C=O)c(F)cc1F.Oc1ccc(Cl)c(C(F)(F)F)c1>>Cc1cc(C=O)c(F)cc1Oc1ccc(Cl)c(C(F)(F)F)c1 -US20080200552A1,6,CCC(CC)(c1ccc(C#CC2(O)CCCC2)c(C)c1)c1ccc(C(=O)NC(C)(C)C(=O)OC)c(C)c1>>CCC(CC)(c1ccc(C#CC2(O)CCCC2)c(C)c1)c1ccc(C(=O)NC(C)(C)C(=O)O)c(C)c1 -US20070129358A1,8,OCC(O)(CC1CCSc2ccccc21)C(F)(F)F>>O=CC(O)(CC1CCSc2ccccc21)C(F)(F)F -US08273769B2,6,Cc1ccncc1C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C>>Cc1ccncc1C#Cc1cc(Cl)ccc1OCC(=O)O -US20070197512A1,6,COC(=O)CCN1C(=S)C(C(C)C)Oc2c(C(C)C)cccc21>>CC(C)c1cccc2c1OC(C(C)C)C(=S)N2CCC(=O)O -US20090042929A1,2,Nc1ccccc1.O=C(O)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1>>O=C(Nc1ccccc1)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1 -US20050113370A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc2c(I)n[nH]c2c1>>CC(C)(C)OC(=O)n1nc(I)c2ccc([N+](=O)[O-])cc21 -US20150023913A1,7,CCOC(=O)C1(C(=O)OCC)CC2=CC(=O)CC2C1>>CCOC(=O)C1(C(=O)OCC)CC2CC(=O)CC2C1 -US20100120763A1,1,Cc1c[nH]cn1.O=[N+]([O-])c1c(F)cc(C(F)(F)F)cc1F>>Cc1cn(-c2cc(C(F)(F)F)cc(F)c2[N+](=O)[O-])cn1 -US20150197509A1,2,CC(C)NCC(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccccc1>>CC(C)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccccc1 -US04788196,1,CS(=O)(=O)Nc1ccc(N2CCNCC2)cc1.O=[N+]([O-])c1ccnc(Cl)c1>>CS(=O)(=O)Nc1ccc(N2CCN(c3cc([N+](=O)[O-])ccn3)CC2)cc1 -US20150232472A1,6,COC(=O)CCc1nc(N2CCCC2)nn1C>>Cn1nc(N2CCCC2)nc1CCC(=O)O -US20100063068A1,3,CNC(=O)c1c(-c2ccc(F)cc2)[nH]c2ccc(Br)cc12.O=C(O)c1cccc(B(O)O)c1>>CNC(=O)c1c(-c2ccc(F)cc2)[nH]c2ccc(-c3cccc(C(=O)O)c3)cc12 -US06787560B2,2,C[SiH](C)OC(c1cccc(CN)c1)C(C)(C)C.O=C(Cl)c1cccc(CCCl)c1>>C[SiH](C)OC(c1cccc(CNC(=O)c2cccc(CCCl)c2)c1)C(C)(C)C -US20070167452A1,1,C=CCCC(CO)CO.Oc1ccc(Cl)cc1>>C=CCCC(CO)COc1ccc(Cl)cc1 -US05929097,6,CCCCCCCCN(C)C(=O)C=Cc1cc(C)c(N(C)S(=O)(=O)c2ccc(OC)cc2)c(C(=O)OC)c1>>CCCCCCCCN(C)C(=O)C=Cc1cc(C)c(N(C)S(=O)(=O)c2ccc(OC)cc2)c(C(=O)O)c1 -US20100240658A1,6,COC(=O)c1cc(-c2noc(-c3ccc(-c4cscc4C)c(C)c3)n2)ccc1O>>Cc1cc(-c2nc(-c3ccc(O)c(C(=O)O)c3)no2)ccc1-c1cscc1C -US20080045537A1,6,COC(=O)c1cccc2[nH]c(CN(C)C3CCCc4cccnc43)nc12>>CN(Cc1nc2c(C(=O)O)cccc2[nH]1)C1CCCc2cccnc21 -US07199155B2,6,CC#CCOc1ccc(S(=O)(=O)Oc2c(C)cccc2C(=O)OC)cc1>>CC#CCOc1ccc(S(=O)(=O)Oc2c(C)cccc2C(=O)O)cc1 -US20120077812A1,3,CC(C)OC(=O)N1CCC(COc2ccc(Br)nc2)CC1.CSc1ccc(B(O)O)c(F)c1>>CSc1ccc(-c2ccc(OCC3CCN(C(=O)OC(C)C)CC3)cn2)c(F)c1 -US08546376B2,6,COc1cc2c(=O)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)oc2cc1C>>COc1cc2c(=O)c(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)oc2cc1C -US04830660,2,CCOC(CN)OCC.S=C=Nc1ccccn1>>CCOC(CNC(=S)Nc1ccccn1)OCC -US04435390,2,CCOCC(=O)O.C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO>>CCOCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C -US20110136800A1,2,O=C(O)c1c[nH]c2ccccc12.c1ccc2c(c1)C[C@@H]1NCCC[C@H]21>>O=C(c1c[nH]c2ccccc12)N1CCC[C@@H]2c3ccccc3C[C@@H]21 -US05530126,1,CO.Cn1nc(-c2cc([N+](=O)[O-])c(F)cc2F)c(Cl)c1C(F)(F)F>>COc1cc(F)c(-c2nn(C)c(C(F)(F)F)c2Cl)cc1[N+](=O)[O-] -US20150038488A1,7,CCC(=O)[C@@H]1CC(=O)N([C@H](C)c2ccc(OC)cc2)C1>>CCC(O)[C@@H]1CC(=O)N([C@H](C)c2ccc(OC)cc2)C1 -US07423159B2,2,CNC.Cn1ncc(/C=C/C(=O)Nc2ccc(CC(=O)O)cc2)c1-c1ccc(F)cc1>>CN(C)C(=O)Cc1ccc(NC(=O)/C=C/c2cnn(C)c2-c2ccc(F)cc2)cc1 -US09156827B2,6,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2O/C(=C\c2c[nH]c4ccc(Br)cc24)C3=O)CC1>>O=C1/C(=C/c2c[nH]c3ccc(Br)cc23)Oc2c1ccc(O)c2CN1CCNCC1 -US07026498B2,3,CCOc1ccc(B(O)O)cc1.O=Cc1ccc(Br)cc1>>CCOc1ccc(-c2ccc(C=O)cc2)cc1 -US05424333,1,CC(C)(C)NNC(=O)c1ccccn1.O=C(Cl)c1ccccc1Br>>CC(C)(C)N(NC(=O)c1ccccn1)C(=O)c1ccccc1Br -US06417203B1,7,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cccc(CC#N)c1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cccc(CCN)c1 -US20060025474A1,2,CCC(O)(C=Cc1ccc(C(CC)(CC)c2ccc(OCC(=O)O)c(C)c2)cc1C)CC.NCCNC(=O)OCC1c2ccccc2-c2ccccc21>>CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(OCC(=O)NCCNC(=O)OCC3c4ccccc4-c4ccccc43)c(C)c2)cc1C)CC -US07589232B2,2,CC(=O)Cl.CCCCCCCCC#Cc1ccc(CNc2ccc3c(c2)C(=O)OC(C)(C)O3)cc1>>CCCCCCCCC#Cc1ccc(CN(C(C)=O)c2ccc3c(c2)C(=O)OC(C)(C)O3)cc1 -US20080214607A1,1,CO.Cn1cc(-c2ccncc2)c(-c2ccc(OCc3cc(Cl)c4ccccc4n3)cc2)n1>>COc1cc(COc2ccc(-c3nn(C)cc3-c3ccncc3)cc2)nc2ccccc12 -US20130116234A1,6,CCN(CC)c1nc2ccc(Cl)cc2c(-c2cccc(Cl)c2)c1C(=O)OC(C)(C)C>>CCN(CC)c1nc2ccc(Cl)cc2c(-c2cccc(Cl)c2)c1C(=O)O -US08829052B2,2,Nc1ccc(F)c(F)c1Nc1ccc(I)cc1F.O=S(=O)(Cl)c1ccc(Cl)s1>>O=S(=O)(Nc1ccc(F)c(F)c1Nc1ccc(I)cc1F)c1ccc(Cl)s1 -US08048909B2,2,CCOC(=O)c1c(Cl)[nH]c(-c2ccccc2)c1F.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)c1c(F)c(-c2ccccc2)n(S(=O)(=O)c2ccccc2)c1Cl -US08012986B2,3,CC(C)(C)NS(=O)(=O)c1cccc(B(O)O)c1.FC(F)(F)c1ccc(-c2cc(C(F)(F)F)nc(-c3ccnc(Cl)c3)n2)cn1>>CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)nc4)cc(C(F)(F)F)n3)ccn2)c1 -US20110319411A1,2,Nc1cccc2c1C(=O)N(c1cccc(C(F)(F)F)c1)C2.O=C(O)c1cnccn1>>O=C(Nc1cccc2c1C(=O)N(c1cccc(C(F)(F)F)c1)C2)c1cnccn1 -US06770748B2,6,CC(=O)O[C@@H]1[C@H](OCc2ccccc2)[C@](COC(C)(C)C)(COS(=O)(=O)c2ccc(C)cc2)O[C@]1(n1cc(C)c(=O)[nH]c1=O)[SiH](c1ccccc1)c1ccccc1>>Cc1ccc(S(=O)(=O)OC[C@]2(COC(C)(C)C)O[C@](n3cc(C)c(=O)[nH]c3=O)([SiH](c3ccccc3)c3ccccc3)[C@H](O)[C@@H]2OCc2ccccc2)cc1 -US20090176823A1,2,CC(C)(C)OC(=O)N(Cc1cc(CC(=O)O)ccc1Cl)C1CC1.CN>>CNC(=O)Cc1ccc(Cl)c(CN(C(=O)OC(C)(C)C)C2CC2)c1 -US20100022570A1,2,NC1CC1(F)c1ccc(Cl)cc1.O=C(Cl)c1ccccc1C(F)(F)F>>O=C(N[C@@H]1C[C@]1(F)c1ccc(Cl)cc1)c1ccccc1C(F)(F)F -US20150011533A1,6,CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(C(F)(F)F)cnc3[nH]cc(NC(=O)c4cnn(Cc5ccc(F)cc5)c4)c23)C1>>N[C@@H]1CCCN(c2c(C(F)(F)F)cnc3[nH]cc(NC(=O)c4cnn(Cc5ccc(F)cc5)c4)c23)C1 -US20040186140A1,6,CC(C)(C)OC(=O)N[C@H]1CCCCN([C@H]2CC[C@@H](N=[N+]=[N-])C[C@H]2CS(=O)(=O)c2ccccc2)C1=O>>[N-]=[N+]=N[C@@H]1CC[C@H](N2CCCC[C@H](N)C2=O)[C@H](CS(=O)(=O)c2ccccc2)C1 -US06821967B2,1,CCCNC(=O)C1(CCCCBr)c2ccccc2-c2ccccc21.Cn1c(N2CCNCC2)nc2ccccc21>>CCCNC(=O)C1(CCCCN2CCN(c3nc4ccccc4n3C)CC2)c2ccccc2-c2ccccc21 -US20100029729A1,6,CCOC(=O)CCNC(=O)c1cn(C)c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(C(=O)NCCC(=O)O)cn(C)c34)no2)cc1Cl -US20080021044A1,6,CCOC(=O)Cn1c(C)cnc(NCC(F)(F)c2ccccc2)c1=O>>Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CC(=O)O -US05691330,1,CC(=O)N1CCc2c(sc(C)c2CCCl)C1.Clc1ccc2nc(N3CCNCC3)sc2c1>>CC(=O)N1CCc2c(sc(C)c2CCN2CCN(c3nc4ccc(Cl)cc4s3)CC2)C1 -US04814343,1,CI.COCc1ccc(OC)c(Br)c1O>>COCc1ccc(OC)c(Br)c1OC -US07595397B2,2,CN=C=O.Cc1ccc(Cl)c(-c2ccc(CN3CCN[C@@H](Cc4ccccc4)C3)cc2)c1>>CNC(=O)N1CCN(Cc2ccc(-c3cc(C)ccc3Cl)cc2)C[C@@H]1Cc1ccccc1 -US20150266854A1,6,COC(=O)c1cc(Br)cc2c1cnn2C1CCCC1>>O=C(O)c1cc(Br)cc2c1cnn2C1CCCC1 -US06696456B1,6,COC(=O)[C@H](NS(=O)(=O)c1ccc(-c2ccc(OC)cc2)cc1)[C@H](OCc1ccc(C)cc1)c1nccs1>>COc1ccc(-c2ccc(S(=O)(=O)N[C@@H](C(=O)O)[C@H](OCc3ccc(C)cc3)c3nccs3)cc2)cc1 -US09139581B2,6,CC(=O)N1CCN(c2ccc(Nc3ncc(F)c(N4CCC(NC(=O)OCc5ccccc5)CC4)n3)cc2)CC1>>CC(=O)N1CCN(c2ccc(Nc3ncc(F)c(N4CCC(N)CC4)n3)cc2)CC1 -US20070049618A1,1,COc1cc(F)ccc1[N+](=O)[O-].OCCN1CCCC1>>COc1cc(OCCN2CCCC2)ccc1[N+](=O)[O-] -US05883102,10,C=Cc1ccccc1C1OCCO1.O>>OCCc1ccccc1C1OCCO1 -US20090221555A1,1,COc1cc2c(cc1N)N(C)C(=O)CN(CC1CC1)C2.CS(=O)(=O)N[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl>>COc1cc2c(cc1Nc1ncc(Cl)c(N[C@@H]3CCCC[C@H]3NS(C)(=O)=O)n1)N(C)C(=O)CN(CC1CC1)C2 -US04140725,1,C=COC.Oc1ccccc1O>>COC(C)Oc1ccccc1O -US20080119462A1,8,CC(=O)Nc1nc(-c2ccc(CO)cc2)c(-c2ccc(S(C)(=O)=O)cc2)s1>>CC(=O)Nc1nc(-c2ccc(C=O)cc2)c(-c2ccc(S(C)(=O)=O)cc2)s1 -US20110306609A1,6,CCOC(=O)c1nc(-c2ccccc2)cs1>>O=C(O)c1nc(-c2ccccc2)cs1 -US20090215759A1,1,COc1cc(N)ccc1-n1cnc(C)c1.Cc1cc(N2CCC(O)CC2)nc(Cl)n1>>COc1cc(Nc2nc(C)cc(N3CCC(O)CC3)n2)ccc1-n1cnc(C)c1 -US20050234096A1,6,CCOC(=O)COc1ccc(S(=O)(=O)N2Cc3cc(OC)ccc3C(C)C2)cc1C>>CCOC(=O)COc1ccc(S(=O)(=O)N2Cc3cc(O)ccc3C(C)C2)cc1C -US20060281772A1,2,COc1cc2ncnc(C3CCNCC3)c2cc1OC.O=C=Nc1ccc(OC(F)(F)F)cc1>>COc1cc2ncnc(C3CCN(C(=O)Nc4ccc(OC(F)(F)F)cc4)CC3)c2cc1OC -US20070054924A1,1,Fc1ccc(Cl)c(Cl)c1.OC1CCNCC1>>Clc1ccc(OC2CCNCC2)cc1Cl -US20060199829A1,3,COC(=O)c1cnc(N2CCc3[nH]c4cc(Br)ccc4c3C2)nc1.O=Cc1cccc(B(O)O)c1>>COC(=O)c1cnc(N2CCc3[nH]c4cc(-c5cccc(C=O)c5)ccc4c3C2)nc1 -US20120015911A1,7,O=Cc1cc2ccccc2s1>>OCc1cc2ccccc2s1 -US20110190205A1,6,COC(=O)CCCCc1nnc(-c2ccccn2)o1>>O=C(O)CCCCc1nnc(-c2ccccn2)o1 -US20090286768A1,1,COc1cc(Br)c(C)cc1O.OB(O)c1ccccc1>>COc1cc(Br)c(C)cc1Oc1ccccc1 -US04535089,2,CC(C)CC(=O)CN.O=C(Cl)c1ccc(F)cc1>>CC(C)CC(=O)CNC(=O)c1ccc(F)cc1 -US20130130289A1,6,CC(C)(C)OC(=O)NCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>[NH3+]CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 -US20070057250A1,1,Brc1ccc(Br)cc1.c1ccc2c(c1)[nH]c1ccccc12>>Brc1ccc(-n2c3ccccc3c3ccccc32)cc1 -US20060211678A1,5,C1=C(c2cc3c(On4nnc5cccnc54)ncnc3[nH]2)CCNC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=C(c2cc3c(On4nnc5cccnc54)ncnc3[nH]2)CC1 -US20100216764A1,1,BrCc1ccc(Br)cc1.CCOC(=O)c1cnn(-c2cccc(-c3ccccc3O)n2)c1C(F)(F)C(F)(F)F>>CCOC(=O)c1cnn(-c2cccc(-c3ccccc3OCc3ccc(Br)cc3)n2)c1C(F)(F)C(F)(F)F -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc4[nH]ccc4c3)c(F)c2)OC1(C)C.C[C@@H](CO)NS(=O)(=O)c1ccccc1Br>>C[C@@H](CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc3[nH]ccc3c2)c(F)c1 -US20100216788A1,1,CC(C)(C)CC(=O)c1cccc(O)c1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>CC(C)(C)CC(=O)c1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1 -US20130331411A1,2,CCCC(=O)Nc1cccc(N)c1.O=C(O)c1ccccc1Br>>CCCC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1 -US05998666,1,O=C(CCCCBr)NC1CCCCCC1.OCCNCc1ccccc1>>O=C(CCCCN(CCO)Cc1ccccc1)NC1CCCCCC1 -US20130029991A1,2,Nc1ccc2ncsc2c1.O=C(O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1>>O=C(CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1)Nc1ccc2ncsc2c1 -US04791118,1,FCCNCC1CCNC1.O=C(O)c1cn(C2CC2)c2c(Cl)c(F)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2c(Cl)c(N3CCC(CNCCF)C3)c(F)cc2c1=O -US20150210682A1,6,CCOC(=O)c1cn2c(cc1=O)-c1cc(F)c(OCCCOC)cc1CC2C(C)C>>COCCCOc1cc2c(cc1F)-c1cc(=O)c(C(=O)O)cn1C(C(C)C)C2 -US08097628B2,8,OCc1cnc(Cl)c(Cl)c1>>O=Cc1cnc(Cl)c(Cl)c1 -US09126998B2,6,Cc1nc2c(OCc3c(F)cccc3F)cc(Cl)cn2c1C(=O)NC1CN(C(=O)OC(C)(C)C)c2ccccc21>>Cc1nc2c(OCc3c(F)cccc3F)cc(Cl)cn2c1C(=O)NC1CNc2ccccc21 -US05330986,2,FC(F)(F)c1cccc(N2CCNCC2)c1.O=C(O)c1cccc2cc[nH]c12>>O=C(c1cccc2cc[nH]c12)N1CCN(c2cccc(C(F)(F)F)c2)CC1 -US20130231321A1,2,C1CCNCC1.O=C(O)c1cnc(C#Cc2ccccc2)s1>>O=C(c1cnc(C#Cc2ccccc2)s1)N1CCCCC1 -US05561128,1,COc1cc(C(=O)CO)ccc1OCCCCl.Fc1ccc2c(C3CCNCC3)noc2c1>>COc1cc(C(=O)CO)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1 -US20040110767A1,2,CC(Nc1ccc(OCCN2CCCC2)cc1)c1ccc(OC2CCCCO2)cc1.Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>Cc1cc(C)c(S(=O)(=O)N(c2ccc(OCCN3CCCC3)cc2)C(C)c2ccc(OC3CCCCO3)cc2)c(C)c1 -US05017608,7,CC1(C)CC(=O)NC2=C1c1ccc(Cl)cc1CC2>>CC1(C)CCNC2=C1c1ccc(Cl)cc1CC2 -US20150175615A1,1,C=CCN1CC(=O)N2[C@@H](Cc3ccc(O)cc3F)C(=O)N(Cc3cccc(F)n3)C[C@@H]2N1C(=O)NCc1ccccc1.C[C@@H]1CN(C2CNC2)CCN1C>>C=CCN1CC(=O)N2[C@@H](Cc3ccc(O)cc3F)C(=O)N(Cc3cccc(N4CC(N5CCN(C)[C@H](C)C5)C4)n3)C[C@@H]2N1C(=O)NCc1ccccc1 -US20050239836A1,6,CC(C)(C)c1cccc(C2(N)CCC3(CC2)OCCO3)c1>>CC(C)(C)c1cccc(C2(N)CCC(=O)CC2)c1 -US04770503,3,C=CCCC[Mg+].N#Cc1ccc([C@@H]2CC[C@@H](CI)CC2)cc1>>C=CCCCC[C@@H]1CC[C@@H](c2ccc(C#N)cc2)CC1 -US20100063037A1,2,COc1cccc2c1C(NC1=Nc3ccc(N)cc3CO1)CC2.O=S(=O)(Cl)N1CCOCC1>>COc1cccc2c1C(NC1=Nc3ccc(NS(=O)(=O)N4CCOCC4)cc3CO1)CC2 -US08053212B1,9,N.O=[N+]([O-])c1ccc(Cl)nc1Cl>>Nc1nc(Cl)ccc1[N+](=O)[O-] -US20150267115A1,3,C#Cc1ccc(CCCC)cc1.CCCc1c(F)cccc1Br>>CCCCc1ccc(C#Cc2cccc(F)c2CCC)cc1 -US20110269960A1,1,CC(C)=O.Oc1cccc(N2CCNCC2)c1>>CC(C)N1CCN(c2cccc(O)c2)CC1 -US06809110B2,6,CCOC(=O)C(Cc1ccc(OC(c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)C(C)C)cc1C)OCC>>CCOC(Cc1ccc(OC(c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)C(C)C)cc1C)C(=O)O -US20110230476A1,2,C=CC(=O)O.COc1c(OCCOCCN)ccc2c1N=C(NC(=O)c1cccnc1)N1CCN=C21>>C=CC(=O)NCCOCCOc1ccc2c(c1OC)N=C(NC(=O)c1cccnc1)N1CCN=C21 -US20090062251A1,2,CN(CCCC(=O)O)C(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1.NC1COC1>>CN(CCCC(=O)NC1COC1)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1 -US20100136136A1,2,Cc1cc(N2CCNCC2)ccc1NC(=O)c1nc[nH]c1C(=O)Nc1nc2ccccc2[nH]1.O=C=Nc1ccccc1>>Cc1cc(N2CCN(C(=O)Nc3ccccc3)CC2)ccc1NC(=O)c1nc[nH]c1C(=O)Nc1nc2ccccc2[nH]1 -US20100261719A1,3,Brc1cccs1.C#Cc1cc(C=O)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F>>C[C@H]1CN(c2c(C=O)cc(C#Cc3cccs3)c(F)c2F)C[C@@H](C)O1 -US08822534B2,6,CCOC(=O)C[C@@H](Cc1ccc(-c2cc(F)ccc2OC)cc1)NC(=O)CCC(=O)O>>COc1ccc(F)cc1-c1ccc(C[C@H](CC(=O)O)NC(=O)CCC(=O)O)cc1 -US20150191478A1,6,CCOC(OCC)c1cc2cncc(-c3ccc(C(=O)OC)cc3)c2o1>>CCOC(OCC)c1cc2cncc(-c3ccc(C(=O)O)cc3)c2o1 -US20080194561A1,1,C=O.O=C1CNCCN1c1cccc([N+](=O)[O-])c1>>CN1CCN(c2cccc([N+](=O)[O-])c2)C(=O)C1 -US20150210688A1,2,Cc1cc(C)c(-c2[nH]c(C3CC3)nc2C)cc1C(=O)O.N#Cc1ccc(C2(F)CNC2)cc1>>Cc1cc(C)c(-c2[nH]c(C3CC3)nc2C)cc1C(=O)N1CC(F)(c2ccc(C#N)cc2)C1 -US06160003,3,Cn1cccc1CC#N.O=C(Cl)c1ccccc1>>Cn1c(CC#N)ccc1C(=O)c1ccccc1 -US05985869,6,CCOC(=O)C1Cc2ccccc2N(C(=O)c2ccc(NC(=O)c3cc(Cl)cc(Cl)c3)cc2)C1>>O=C(Nc1ccc(C(=O)N2CC(C(=O)O)Cc3ccccc32)cc1)c1cc(Cl)cc(Cl)c1 -US07368578B2,7,COc1cc(C=O)ccc1OCc1nc(-c2cccc([N+](=O)[O-])c2)oc1C>>COc1cc(CO)ccc1OCc1nc(-c2cccc([N+](=O)[O-])c2)oc1C -US20050267095A1,7,N#CC1(c2ccc(OC3CCN(C4CCC4)CC3)cc2)CCOCC1>>NCC1(c2ccc(OC3CCN(C4CCC4)CC3)cc2)CCOCC1 -US20040024215A1,1,CC(Br)c1ccccc1.O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>CC(c1ccccc1)N1CCN(c2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)CC1 -US07851463B2,7,CCCN1CCCC(c2ccc([N+](=O)[O-])cc2)C1>>CCCN1CCCC(c2ccc(N)cc2)C1 -US07179823B1,1,CCOC(=O)Cc1c[nH]nc1-c1ccccc1.ClCc1ccc(OCc2csc(-c3ccccc3)n2)nc1>>CCOC(=O)Cc1cn(Cc2ccc(OCc3csc(-c4ccccc4)n3)nc2)nc1-c1ccccc1 -US20120116095A1,1,NC1CCC1.O=Cc1ccc(F)c(-c2cccc(CO)c2)c1>>OCc1cccc(-c2cc(CNC3CCC3)ccc2F)c1 -US05770595,8,CC(O)CCCCCCCCCCCCCCCn1c(=O)c2c(ncn2C)n(C)c1=O>>CC(=O)CCCCCCCCCCCCCCCn1c(=O)c2c(ncn2C)n(C)c1=O -US20060014790A1,6,CC(C)(C)OC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cc(I)cc(C(C)(C)C)c2)CCCCC1>>CC(C)(C)c1cc(I)cc(C2(NCC(O)C(N)Cc3cc(F)cc(F)c3)CCCCC2)c1 -US20090264482A1,1,ClCc1cscn1.N#Cc1ccc2[nH]ccc2c1C(F)(F)F>>N#Cc1ccc2c(ccn2Cc2cscn2)c1C(F)(F)F -US20060241127A1,1,Nc1ccc(Oc2ccnc3c2CCN3)c(F)c1.Nc1nc(Cl)cc(-c2ccc(F)cc2)n1>>Nc1nc(Nc2ccc(Oc3ccnc4c3CCN4)c(F)c2)cc(-c2ccc(F)cc2)n1 -US05977101,9,NC(=O)c1cc2ccccc2[nH]1>>N#Cc1cc2ccccc2[nH]1 -US20140135508A1,4,CC1(C)OC(C)(C)C(=Cc2cc(-c3ccc(Cl)cc3)ccc2Br)C1=O.OO>>CC1(C)OC(C)(C)C2(OC2c2cc(-c3ccc(Cl)cc3)ccc2Br)C1=O -US20020103203A1,6,CCOC(=O)c1cccc(CCc2cncc3ccccc23)c1>>O=C(O)c1cccc(CCc2cncc3ccccc23)c1 -US07425641B2,2,CN(C)Cc1ccc(CN)cc1.N#Cc1cccc(C(=O)Cl)c1>>CN(C)Cc1ccc(CNC(=O)c2cccc(C#N)c2)cc1 -US20090227799A1,7,O=Cc1cccc(Sc2ccccc2)c1>>OCc1cccc(Sc2ccccc2)c1 -US04782176,6,CCCc1c(O)c(C(C)=O)cc(Cl)c1OCCCOCCCOc1c(C(C)=O)ccc(OCCCC(=O)OCC)c1CCC>>CCCc1c(O)c(C(C)=O)cc(Cl)c1OCCCOCCCOc1c(C(C)=O)ccc(OCCCC(=O)O)c1CCC -US08188101B2,6,COc1cccc(Cc2nc(Nc3ccc(-n4cnc(C)c4)c(OC)c3)nc3c2CN(C(=O)OC(C)(C)C)CC3)c1>>COc1cccc(Cc2nc(Nc3ccc(-n4cnc(C)c4)c(OC)c3)nc3c2CNCC3)c1 -US20130274266A1,2,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)Cn2c1nc(Cl)c2C#N.N#Cc1ccc(C(=O)O)nc1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)Cn2c1nc(Cl)c2C#N -US07388019B2,7,COc1nc(C(F)(F)F)c(Br)c(C=O)c1Br>>COc1nc(C(F)(F)F)c(Br)c(CO)c1Br -US20100055071A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C(NC1CC1)c1cccc(Br)c1>>CC1(C)OB(c2cccc(C(=O)NC3CC3)c2)OC1(C)C -US20140336106A1,2,COc1ccc([C@@H](O)[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)O)cc1.C[C@]1(C(=O)[C@@H](N)CC2CCCC2)CO1>>COc1ccc([C@@H](O)[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC2CCCC2)C(=O)[C@@]2(C)CO2)cc1 -US20110046134A1,2,NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1.O=C(O)c1ccc(-c2ccccc2)cc1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1ccc(-c2ccccc2)cc1 -US08877744B2,3,Brc1cn(-c2ccccn2)cn1.COc1ccc(C(NC2=N[C@](C)(c3cc(B4OCC(C)(C)CO4)ccc3F)C(F)(F)C(C)(C)OC2)(c2ccccc2)c2ccc(OC)cc2)cc1>>COc1ccc(C(NC2=N[C@](C)(c3cc(-c4cn(-c5ccccn5)cn4)ccc3F)C(F)(F)C(C)(C)OC2)(c2ccccc2)c2ccc(OC)cc2)cc1 -US07786121B2,6,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1>>O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCNCC1 -US04769386,8,COc1ccc(CSc2nc(C)c(CO)n2C)cc1>>COc1ccc(CSc2nc(C)c(C=O)n2C)cc1 -US05728686,1,CCI.CCOP(=O)(CCCCn1c(=O)c2[nH]cnc2n(C)c1=O)OCC>>CCOP(=O)(CCCCn1c(=O)c2c(ncn2CC)n(C)c1=O)OCC -US20070219198A1,1,O=S(=O)(c1cccc(Cl)c1)C1CCNCC1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1N1CCC(S(=O)(=O)c2cccc(Cl)c2)CC1 -US20090099205A1,1,Cc1cccc(CN)c1.Cc1ncnc(C)c1C(=O)NCCC(C)N1CCC(=O)CC1>>Cc1cccc(CNC2CCN(C(C)CCNC(=O)c3c(C)ncnc3C)CC2)c1 -US04220781,1,BrCc1ccccn1.C1CCNC1>>c1ccc(CN2CCCC2)nc1 -US04427665,6,CC(C)(C)C(=O)OCOP(=O)(CCCCc1ccccc1)CC(=O)N1Cc2ccccc2C[C@H]1C(=O)OCc1ccccc1>>CC(C)(C)C(=O)OCOP(=O)(CCCCc1ccccc1)CC(=O)N1Cc2ccccc2C[C@H]1C(=O)O -US20110257151A1,6,CCN1CCCC1CNC(=O)c1cccc(C2Nc3ccc(C(=O)OC)cc3CC2(C)C)c1>>CCN1CCCC1CNC(=O)c1cccc(C2Nc3ccc(C(=O)O)cc3CC2(C)C)c1 -US20140243324A1,2,Nc1ccc(-n2ncc3cc(OCc4ccccc4)ccc32)cc1.O=C(O)c1ccc(N2CCC(O)CC2)cc1>>O=C(Nc1ccc(-n2ncc3cc(OCc4ccccc4)ccc32)cc1)c1ccc(N2CCC(O)CC2)cc1 -US20070213348A1,3,COc1ccc(C(=O)c2ccc(C#N)cc2)cc1.O=C1CCCCCC1>>COc1ccc(C(=C2CCCCCC2)c2ccc(C#N)cc2)cc1 -US20130090323A1,1,CS(=O)(=O)Nc1cccc(-c2cnc(N3CCOCC3)cc2N)c1.Cc1c(-c2ccccn2)nc2cc(F)ccc2c1Cl>>Cc1c(-c2ccccn2)nc2cc(F)ccc2c1Nc1cc(N2CCOCC2)ncc1-c1cccc(NS(C)(=O)=O)c1 -US04299832,1,BrCCCOc1ccccc1.CCc1nc2c([nH]1)c(=O)n(C)c(=O)n2C>>CCc1nc2c(c(=O)n(C)c(=O)n2C)n1CCCOc1ccccc1 -US04983755,1,CNN=C(c1ccc(Cl)cc1)C(C)(C)C.COC(=O)Cl>>COC(=O)N(C)N=C(c1ccc(Cl)cc1)C(C)(C)C -US20130005707A1,7,O=[N+]([O-])c1ccc(N2CCOCC2)nc1>>Nc1ccc(N2CCOCC2)nc1 -US20120264733A1,1,CCCN(C(=O)c1nc2ccccc2[nH]1)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1.COCCCCOS(C)(=O)=O>>CCCN(C(=O)c1nc2ccccc2n1CCCCOC)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1 -US20140378475A1,4,CCOC(=O)C1CCCC(=O)C1.NNc1cc(Br)c(F)cc1C(=O)O>>CCOC(=O)C1CCc2c([nH]c3c(C(=O)O)cc(F)c(Br)c23)C1 -US20090233900A1,9,CC(C)(C)c1ccc(C(=O)O)c(F)c1.N>>CC(C)(C)c1ccc(C(N)=O)c(F)c1 -US20090149445A1,3,Clc1ccc2c(c1)CCc1ccccc1C2=CBr.OB(O)c1cccc(O)c1>>Oc1cccc(C=C2c3ccccc3CCc3cc(Cl)ccc32)c1 -US20120258964A1,1,C1COCCN1.O=Cc1ccc(-c2ccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc3c2)cc1>>O=C(N[C@H]1CN2CCC1CC2)c1cc2ccc(-c3ccc(CN4CCOCC4)cc3)cc2s1 -US20090233929A1,3,CON(C)C(=O)c1cn(-c2cccc(-c3cccnc3F)c2)cn1.Cc1ccnc(Br)c1>>Cc1ccnc(C(=O)c2cn(-c3cccc(-c4cccnc4F)c3)cn2)c1 -US20100029752A1,6,CCCCCCCCNC(=O)c1cc(OCC(=O)OC(C)(C)C)cs1>>CCCCCCCCNC(=O)c1cc(OCC(=O)O)cs1 -US20100286211A1,1,Brc1ccc(Br)nc1.c1c[nH]cn1>>Brc1ccc(-n2ccnc2)nc1 -US07655686B2,2,CC(C)c1cccc(CNC[C@@H](O)[C@@H](N)Cc2ccccc2)c1.CCCN1CCC[C@@]12CCN([C@@H](C)C(=O)O)C2=O>>CCCN1CCC[C@@]12CCN([C@@H](C)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1cccc(C(C)C)c1)C2=O -US04943578,2,O=C(O)Cc1ccc(Cl)c(Cl)c1.OCC1CN(Cc2ccccc2)CCN1>>O=C(Cc1ccc(Cl)c(Cl)c1)N1CCN(Cc2ccccc2)CC1CO -US20150266895A1,1,COc1ccc(CN2CCc3nc(Cl)cc4c3c2nn4C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.C[C@@H](NC(N)=O)c1ccccc1>>COc1ccc(CN2CCc3nc(NC(=O)N[C@H](C)c4ccccc4)cc4c3c2nn4C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US05736540,7,O=C(c1ccc([N+](=O)[O-])cc1)N1Cc2nccn2Cc2ccccc21>>Nc1ccc(C(=O)N2Cc3nccn3Cc3ccccc32)cc1 -US20090099161A1,6,COCc1nc2c(N)nc3cc(CCC(=O)N(C)C)ccc3c2n1CC(C)(C)O>>CN(C)C(=O)CCc1ccc2c(c1)nc(N)c1nc(CO)n(CC(C)(C)O)c12 -US20070185103A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCOC(C(=O)O)C1>>CC(C)(C)OC(=O)N1CCOC(C(=O)OCc2ccccc2)C1 -US20110046143A1,6,CN(C(=O)OC(C)(C)C)C1CCN(c2nnc(Cl)c3ccccc23)CC1>>CNC1CCN(c2nnc(Cl)c3ccccc23)CC1 -US20130060027A1,3,C=CC(=O)N1C(=O)OC[C@H]1c1ccccc1.COc1ccc(Br)c(C2OCCO2)c1>>COc1ccc(/C=C/C(=O)N2C(=O)OC[C@H]2c2ccccc2)c(C2OCCO2)c1 -US20110257395A1,1,ClCCCN1CCCC1>>C1CC[N+]2(C1)CCC2 -US20130324576A1,2,Cc1nn(C)c(C)c1S(=O)(=O)Cl.c1ccc(OC2CCNCC2)cc1>>Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccccc2)CC1 -US06852726B2,1,CS(=O)(=O)c1c[nH]c2c(Cl)cccc12.N#CCBr>>CS(=O)(=O)c1cn(CC#N)c2c(Cl)cccc12 -US20030064320A1,3,C=C[Si](OC)(OC)OC.CC(C)(C)OC(=O)Oc1ccc(Br)cc1>>CO[Si](C=Cc1ccc(OC(=O)OC(C)(C)C)cc1)(OC)OC -US20080146572A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(CCCN3CCOCC3)cc2)CC1>>c1cc(N2CCNCC2)ccc1CCCN1CCOCC1 -US08518972B2,1,CCC1CCNCC1.COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CBr)cc3)cccc2C1=O>>CCC1CCN(Cc2ccc(COc3cccc4c3CN(C(CCC(=O)OC)C(N)=O)C4=O)cc2)CC1 -US08501780B2,1,C1COCCN1.NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)n[nH]c12>>NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCN(S(=O)(=O)CCCN4CCOCC4)CC3)n[nH]c12 -US08362073B2,7,COC(=O)C1(NC(=O)c2ccc(OC)c([N+](=O)[O-])c2)Cc2ccccc2C1>>COC(=O)C1(NC(=O)c2ccc(OC)c(N)c2)Cc2ccccc2C1 -US06355806B1,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CC=C3C#Cc2ccccc2)cc1>>CC1(C)CC=C(C#Cc2ccccc2)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 -US05342846,1,COc1c(F)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12.Cc1cn(C2CCNC2)nn1>>COc1c(N2CCC(n3cc(C)nn3)C2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12 -US20110021352A1,3,CB(O)O.CCOC(=O)c1cc2c(Cl)c(F)cnc2nc1C(F)(F)F>>CCOC(=O)c1cc2c(C)c(F)cnc2nc1C(F)(F)F -US20020133008A1,6,CCOC(=O)c1c(Cl)nc2nn(Cc3ccc(OC)cc3)cc2c1N>>COc1ccc(Cn2cc3c(N)c(C(=O)O)c(Cl)nc3n2)cc1 -US04904690,6,CCOC(=O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12>>O=C(O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12 -US20080182891A1,7,Cc1ccc(S(=O)(=O)OC[C@H]2C=Cc3ccc(F)c(-c4ccccc4Cl)c3O2)cc1>>Cc1ccc(S(=O)(=O)OC[C@H]2CCc3ccc(F)c(-c4ccccc4Cl)c3O2)cc1 -US20040167176A1,2,CC(C)Cc1cc(-c2ccc(Cn3ccnc3)cc2)c(S(N)(=O)=O)s1.CCCCOC(=O)Cl>>CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 -US07977485B2,2,Nc1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1.O=C(Cl)C1CCCC1>>O=C(N[C@H]1CN2CCC1CC2)c1cc2cccc(-c3cccc(NC(=O)C4CCCC4)c3)c2s1 -US04935426,1,CC(C)(C)C1CCC(N2CCNCC2)CC1.CC1(C)CCCC(=O)C1>>CC1(C)CCCC(N2CCN(C3CCC(C(C)(C)C)CC3)CC2)C1 -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1nc(-c2cc(C)c(Br)c(C)c2)no1>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(-c6noc(C)n6)cc5C)ccc(F)c43)ccc21 -US05382590,2,Cc1cccc(N=C=O)c1.NCC(=O)N(CC(=O)NCc1ccccc1)c1ccccc1>>Cc1cccc(NC(=O)NCC(=O)N(CC(=O)NCc2ccccc2)c2ccccc2)c1 -US07741316B2,8,Clc1ccc(C(c2ccc(Cl)cc2)N2CC(Sc3ccccc3)C2)cc1.O=C(OO)c1cccc(Cl)c1>>O=S(c1ccccc1)C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1 -US04460596,6,CCOC(=O)Cc1nc(-c2ccc(Cl)cc2)oc1-c1ccsc1>>O=C(O)Cc1nc(-c2ccc(Cl)cc2)oc1-c1ccsc1 -US20070259851A1,3,C=C[Sn](CCCC)(CCCC)CCCC.O=[N+]([O-])c1cccnc1Cl>>C=Cc1ncccc1[N+](=O)[O-] -US20130065897A1,2,NCCCO.O=Cc1ccc(-c2ccc(C(=O)O)cc2)s1>>O=Cc1ccc(-c2ccc(C(=O)NCCCO)cc2)s1 -US20080032998A1,2,O=C(O)c1cc2ncc(Br)cn2n1.O=[N+]([O-])c1ccccc1C1=CCNCC1>>O=C(c1cc2ncc(Br)cn2n1)N1CC=C(c2ccccc2[N+](=O)[O-])CC1 -US20120270892A1,3,O=Cc1nc(Br)ccc1F.OB(O)c1ccco1>>O=Cc1nc(-c2ccco2)ccc1F -US20110212968A1,1,COc1cc(CCN)cc(OC)c1OC.O=CC1CC1>>COc1cc(CCNCC2CC2)cc(OC)c1OC -US07365076B2,6,COc1cccc(-c2ccc(C(CN3CCN(C(=O)OC(C)(C)C)CC3)C3(O)CCCCC3)cc2)c1>>COc1cccc(-c2ccc(C(CN3CCNCC3)C3(O)CCCCC3)cc2)c1 -US20070027178A1,6,Cc1cc(C)c2c3c(n(C)c2c1)CCN(C(=O)OC(C)(C)C)C3>>Cc1cc(C)c2c3c(n(C)c2c1)CCNC3 -US06759547B1,7,CCOC(=O)C(F)=C(CC)c1cc2c(cc1OCOC)C(C)(C)CCC2(C)C>>CC/C(=C(\F)CO)c1cc2c(cc1OCOC)C(C)(C)CCC2(C)C -US20100059741A1,3,COc1ccc(B(O)O)cc1.Cc1cnc(Cl)c(C)n1>>COc1ccc(-c2ncc(C)nc2C)cc1 -US08110687B2,2,CNC(=O)c1cc(Oc2ccc3c(c2)CC(N)CC3)ccn1.COc1ccc(C(=O)O)cc1F>>CNC(=O)c1cc(Oc2ccc3c(c2)CC(NC(=O)c2ccc(OC)c(F)c2)CC3)ccn1 -US07375099B2,6,CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCc2ccccc2C1>>NC(Cc1c[nH]c2ccccc12)C(=O)N1CCc2ccccc2C1 -US20110112120A9,1,CCCCc1nc(CC)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OB(O)c1ccccc1>>CCCCc1nc(CC)n(-c2ccccc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20100081825A1,2,COCc1ccc2ccc(CN3CCC(N)CC3)cc2c1.COc1ccc(C(=O)O)cc1F>>COCc1ccc2ccc(CN3CCC(NC(=O)c4ccc(OC)c(F)c4)CC3)cc2c1 -US05100761,2,Nc1cccc(-n2nnnc2S)c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cccc(-n2nnnc2S)c1)Oc1ccccc1 -US05912273,9,ClC(Cl)(Cl)Cl.OCC/C(=C(\c1ccccc1)c1ccc(OCCOCc2ccccc2)cc1)c1ccccc1>>ClCC/C(=C(\c1ccccc1)c1ccc(OCCOCc2ccccc2)cc1)c1ccccc1 -US06384051B1,1,CCOc1cc2ncc(C#N)c(Cl)c2cc1OCC.NCc1cccc(Br)c1>>CCOc1cc2ncc(C#N)c(NCc3cccc(Br)c3)c2cc1OCC -US20120289501A1,1,CN1CCNCC1=O.Nc1ncnc2c1c(-c1ccc3c(c1)OC(c1ccccc1)CC3)cn2C1CCC(=O)CC1>>CN1CCN([C@@H]2CC[C@H](n3cc(-c4ccc5c(c4)OC(c4ccccc4)CC5)c4c(N)ncnc43)CC2)CC1=O -US20080027050A1,6,CCOC(=O)c1ccc(COCc2csc3nc(C(=O)NCc4cccc(COC)c4)[nH]c(=O)c23)cc1>>COCc1cccc(CNC(=O)c2nc3scc(COCc4ccc(C(=O)O)cc4)c3c(=O)[nH]2)c1 -US20120245169A1,3,CCOC(=O)CN(C(=O)c1c(C)cccc1C=O)C(C)C>>CCOC(=O)c1cc2cccc(C)c2c(=O)n1C(C)C -US04649146,2,CCN1CCCC1CN.CCOC(=O)c1nc(NC)sc1-c1ccncc1>>CCN1CCCC1CNC(=O)c1nc(NC)sc1-c1ccncc1 -US08349831B2,2,COc1ccc(C(=O)O)cc1S(=O)(=O)N1CCOCC1.C[C@@H](N)c1cccc(Cl)c1>>COc1ccc(C(=O)N[C@H](C)c2cccc(Cl)c2)cc1S(=O)(=O)N1CCOCC1 -US03992408,6,Cc1nc2n(c1CN1C(=O)c3ccccc3C1=O)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>Cc1nc2n(c1CN)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2 -US20100234351A1,7,CC(C)(C)OC(=O)NCCSC(C)(C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCSC(C)(C)CO -US20150252044A1,1,C1COCCN1.COC(=O)c1ccc2cncc(Br)c2n1>>COC(=O)c1ccc2cncc(N3CCOCC3)c2n1 -US20140364414A1,3,Brc1cnc(N2CCOCC2)c2nc(/C=C/c3ccc4ccccc4n3)cn12.CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1>>CC(C)(C)OC(=O)Nc1ccc(-c2cnc(N3CCOCC3)c3nc(/C=C/c4ccc5ccccc5n4)cn23)cn1 -US08143237B2,9,CCOC(=O)c1[se]c2ncccc2c1N=NN(C)C.[NH4+]>>CN(C)N=Nc1c(C(N)=O)[se]c2ncccc12 -US04661617,3,CC(C)C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.CCOC(=O)C=C(C)COc1ccc(C=O)cc1OC>>CCOC(=O)C=C(C)COc1ccc(C=CC(C)C)cc1OC -US06310203B1,1,Brc1cccc(COC2CCCCO2)n1.c1c[nH]cn1>>c1cc(COC2CCCCO2)nc(-n2ccnc2)c1 -US07687491B2,6,COC(=O)C1CN(Cc2ccc(-c3noc(-c4ccc(CC(C)C)c(Cl)c4)n3)cn2)C1>>CC(C)Cc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)nc3)no2)cc1Cl -US07507760B2,2,NC1CCN(C(c2ccccc2)c2ccccc2)C1=O.O=C(O)CC(c1ccccc1)c1ccccc1>>O=C(CC(c1ccccc1)c1ccccc1)NC1CCN(C(c2ccccc2)c2ccccc2)C1=O -US05532258,6,COCCNC(N)=Nc1nc(-c2cccc(CNC(=O)CNC(=O)OC(C)(C)C)c2)cs1>>COCCNC(N)=Nc1nc(-c2cccc(CNC(=O)CN)c2)cs1 -US05756505,1,CC(C)Cc1cc(C(=O)N2CCN(CC(C)C)CC2)ccc1O.COc1ccc(CBr)cc1>>COc1ccc(COc2ccc(C(=O)N3CCN(CC(C)C)CC3)cc2CC(C)C)cc1 -US20040167155A1,6,COc1ccc(S(=O)(=O)N2c3cc(F)ccc3-c3ccccc3C2C)cc1>>CC1c2ccccc2-c2ccc(F)cc2N1S(=O)(=O)c1ccc(O)cc1 -US20030186970A1,1,COc1ccc(C=O)cc1.O=[N+]([O-])c1ccc2c(c1)OCCN2>>COc1ccc(CN2CCOc3cc([N+](=O)[O-])ccc32)cc1 -US06969730B2,1,CS(=O)(=O)OCCc1cc2cc(-c3ccc(C#N)cc3)ccc2o1.c1c[nH]cn1>>N#Cc1ccc(-c2ccc3oc(CCn4ccnc4)cc3c2)cc1 -US20150045339A1,1,N#Cc1ccc(Nc2ncc(C#CCCCN3C(=O)c4ccccc4C3=O)c(NCCCO)n2)cc1>>N#Cc1ccc(Nc2ncc(C#CCCCN3C(=O)c4ccccc4C3=O)c(N3CCC3)n2)cc1 -US20090118284A1,2,COC(=O)c1ccc(Br)c(F)c1.NN>>NNC(=O)c1ccc(Br)c(F)c1 -US20030073833A1,2,Cc1nc(NC(=O)OC(C)(C)C)ccc1CN.O=C(O)Cc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F>>Cc1nc(NC(=O)OC(C)(C)C)ccc1CNC(=O)Cc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F -US08889670B2,1,CC(C)(C)c1cc(NC(=O)C2CNCCO2)no1.FC(F)(F)c1ccc(Br)nc1>>CC(C)(C)c1cc(NC(=O)C2CN(c3ccc(C(F)(F)F)cn3)CCO2)no1 -US20140128390A1,3,CC1(C)OB(c2cnn(CCN3CCOCC3)c2)OC1(C)C.Clc1ncnc2cc(Br)sc12>>Clc1ncnc2cc(-c3cnn(CCN4CCOCC4)c3)sc12 -US20020013328A1,9,COC(=O)c1ccc(CBr)cc1.[C-]#N>>COC(=O)c1ccc(CC#N)cc1 -US20150218170A1,1,CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12.CS(=O)(=O)c1cccc(N)c1>>CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Nc3cccc(S(C)(=O)=O)c3)nc12 -US20080207882A1,1,CC(=O)OC[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.O=C(c1ccc(OC(F)(F)F)cc1)c1sccc1O>>CC(=O)OCC1OC(Oc2ccsc2C(=O)c2ccc(OC(F)(F)F)cc2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O -US08269002B2,6,CCOC(=O)CN1CCN(S(=O)(=O)Nc2cc(OC)nc(SCc3cccc(F)c3F)n2)CC1>>COc1cc(NS(=O)(=O)N2CCN(CC(=O)O)CC2)nc(SCc2cccc(F)c2F)n1 -US20150065534A1,6,COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cc(OCCCN)cc2Cl)cc1)NC(=O)c1ccc(C(=O)NCc2cccc(O)c2)cc1Cl>>NCCCOc1cc(Cl)c(C(=O)Nc2ccc(C[C@H](NC(=O)c3ccc(C(=O)NCc4cccc(O)c4)cc3Cl)C(=O)O)cc2)c(Cl)c1 -US04873339,7,C[C@@H](c1ccccc1)n1c2c([nH]c1=O)C(=O)OC2>>C[C@@H](c1ccccc1)N1C(=O)N[C@@H]2C(=O)OC[C@@H]21 -US05134128,7,OCCCC#Cc1ccccn1>>OCCCCCc1ccccn1 -US05436221,1,BrCc1ccccc1.O=C([O-])CCCO>>O=C(CCCO)OCc1ccccc1 -US20110172245A1,2,CC(=O)Cl.CC(C)(C#N)c1cccc(C(=O)Nc2ccc(F)c(Oc3ccc4nc(N)sc4c3)c2)c1Cl>>CC(=O)Nc1nc2ccc(Oc3cc(NC(=O)c4cccc(C(C)(C)C#N)c4Cl)ccc3F)cc2s1 -US20080119466A1,2,CCCCC(=O)OC(=O)CCCC.Nc1ncnc2c1ncn2-c1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1>>CCCCC(=O)Nc1ncnc2c1ncn2-c1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1 -US20030083315A1,1,CCOC(=O)CCCSc1nc2ccccc2[nH]1.ClCc1cccc2ccccc12>>CCOC(=O)CCCSc1nc2ccccc2n1Cc1cccc2ccccc12 -US20130109682A1,7,CC1OC(c2ccncc2[N+](=O)[O-])C(F)C(=O)C1(C)O[Si](C)(C)C>>CC1OC(c2ccncc2N)C(F)C(=O)C1(C)O[Si](C)(C)C -US04845097,1,C1COCCN1.Cc1cc(CCBr)ccc1OCCNc1ncnc(C)c1Cl>>Cc1cc(CCN2CCOCC2)ccc1OCCNc1ncnc(C)c1Cl -US20060035892A1,1,COCCOCCO.Cc1nc2c3c(ccn2c1C)[C@@H](O)[C@H](O)[C@@H](c1ccccc1)N3>>COCCOCCO[C@@H]1c2ccn3c(C)c(C)nc3c2N[C@H](c2ccccc2)[C@H]1O -US05789423,2,CC(=O)OC(C)=O.COc1ccc(C2(N)CC2)cc1>>COc1ccc(C2(NC(C)=O)CC2)cc1 -US07498325B2,6,CCN1CCC(C2CCN(C(=O)OCc3ccccc3)CC2)CC1>>CCN1CCC(C2CCNCC2)CC1 -US20150126555A1,1,COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CCCCN2)cc1.O=CCOc1ccc(F)cc1>>COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CCCCN2CCOc2ccc(F)cc2)cc1 -US07902252B2,6,COC(=O)c1cc2c([nH]1)CCC2Cc1ccc(F)cc1C>>Cc1cc(F)ccc1CC1CCc2[nH]c(C(=O)O)cc21 -US04892873,1,CC(=O)Nc1cccc(-c2ccc3nncn3n2)c1.CCI>>CCN(C(C)=O)c1cccc(-c2ccc3nncn3n2)c1 -US20140107340A1,2,CC(CN)(CC1CC1)c1cnc(C(F)(F)F)nc1.O=C(O)c1cccc(Cl)c1Cl>>CC(CNC(=O)c1cccc(Cl)c1Cl)(CC1CC1)c1cnc(C(F)(F)F)nc1 -US20100168192A1,2,NS(=O)(=O)C(F)(F)F.O=C(O)Cc1noc2ccccc12>>O=C(Cc1noc2ccccc12)NS(=O)(=O)C(F)(F)F -US20150141641A1,1,COC(=O)c1cc(F)ccc1NS(=O)(=O)c1ccc(C)cc1.N#CCCCCl>>COC(=O)c1cc(F)ccc1N(CCCC#N)S(=O)(=O)c1ccc(C)cc1 -US20120321559A1,7,Brc1cccc(C2=NCCC2)c1>>Brc1cccc(C2CCCN2)c1 -US20150232445A1,3,COC(=O)N1c2ccc(B3OC(C)(C)C(C)(C)O3)c(OC3CCC3)c2CC[C@@H]1C.Fc1c(Br)cnn1C1CCN(Cc2ccccc2)CC1>>COC(=O)N1c2ccc(-c3cnn(C4CCN(Cc5ccccc5)CC4)c3F)c(OC3CCC3)c2CC[C@@H]1C -US20100210642A1,3,C#Cc1cnc2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)cn12.NS(=O)(=O)c1cc(Br)c(F)cc1F>>NS(=O)(=O)c1cc(C#Cc2cnc3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)cn23)c(F)cc1F -US06632816B1,1,CC(C)C=O.CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](N)Cc1ccc2ccccc2c1)S(=O)(=O)c1ccc(N)cc1>>CC(C)CN[C@@H](Cc1ccc2ccccc2c1)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 -US20130022665A1,1,CCCCCCCC/C=C\CCCCCCCC(=O)OCCCN(CCCOC(=O)CCCCCCC/C=C\CCCCCCCC)C(=O)CN(C)C.OCCBr>>CCCCCCCC/C=C\CCCCCCCC(=O)OCCCN(CCCOC(=O)CCCCCCC/C=C\CCCCCCCC)C(=O)C[N+](C)(C)CCO -US20100130446A1,1,C1COCCN1.O=Cc1nnc(-c2ccc(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)s1>>O=S(=O)(c1ccc(C(CC2CCOCC2)c2ccc(-c3nnc(CN4CCOCC4)s3)[nH]2)cc1)C1CC1 -US06265404B1,6,CCOC(=O)C1(N(C)c2c(F)c(Oc3cccc(C4=NCCN4C)c3)nc(Oc3cc(C(=N)N)ccc3O)c2F)CCCC1>>CN1CCN=C1c1cccc(Oc2nc(Oc3cc(C(=N)N)ccc3O)c(F)c(N(C)C3(C(=O)O)CCCC3)c2F)c1 -US20140296136A1,2,C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)O.COCC1(S(N)(=O)=O)CC1>>C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)NS(=O)(=O)C1(COC)CC1 -US20060235056A1,6,COC(=O)C1=C(c2ccc(CCCO[Si](C)(C)C(C)(C)C)cc2)CCN(C(=O)OC(C)(C)C)C1>>COC(=O)C1=C(c2ccc(CCCO)cc2)CCN(C(=O)OC(C)(C)C)C1 -US07468368B2,1,O=c1[nH]ncc(Cl)c1Cl.c1ccc(CN2CCNCC2)cc1>>O=c1[nH]ncc(N2CCN(Cc3ccccc3)CC2)c1Cl -US20130313538A1,3,Brc1cccc(I)c1.OB(O)c1cccc2c1oc1ccccc12>>Brc1cccc(-c2cccc3c2oc2ccccc23)c1 -US07105671B2,2,Nc1nccs1.O=C(O)[C@H](CC1CCCCO1)c1ccc(Cl)c(Cl)c1>>O=C(Nc1nccs1)[C@H](CC1CCCCO1)c1ccc(Cl)c(Cl)c1 -US03948947,2,CN(C(=O)Cl)C1c2ccccc2Oc2ccccc21.CN(C)N>>CN(C)NC(=O)N(C)C1c2ccccc2Oc2ccccc21 -US08173682B2,1,CCc1cc(Br)c(C)nc1OC.c1c[nH]cn1>>CCc1cc(-n2ccnc2)c(C)nc1OC -US07618978B2,1,CCCS.COC(=O)c1cc(Cl)nc(Cl)c1>>CCCSc1cc(C(=O)OC)cc(Cl)n1 -US20090264445A1,2,CC(C)C[C@@H](C(=O)O)N1CC(Oc2cccc(Br)c2F)=CC1=O.CC1(C)OC[C@@H](Cn2ccc(N)n2)O1>>CC(C)C[C@@H](C(=O)Nc1ccn(C[C@@H]2COC(C)(C)O2)n1)N1CC(Oc2cccc(Br)c2F)=CC1=O -US20110201584A1,6,C[C@@H](NC(=O)OC(C)(C)C)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@@H](c5ccc(=O)oc5)CC[C@]4(O)[C@@H]3CC[C@@H]2C1>>C[C@@H](N)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@@H](c5ccc(=O)oc5)CC[C@]4(O)[C@@H]3CC[C@@H]2C1 -US06607710B1,1,O=C(Cl)c1ccccc1.O=C(O)CS>>O=C(O)CSC(=O)c1ccccc1 -US05994362,6,CCOC(=O)CCCOc1ccccc1OCc1ccccc1>>CCOC(=O)CCCOc1ccccc1O -US20120295915A1,3,Cc1ccccc1B(O)O.O=Cc1ccc(Br)cc1>>Cc1ccccc1-c1ccc(C=O)cc1 -US20040235666A1,1,CC(Cl)c1ccc(Cl)cc1.N#CN=C1NCCN1>>CC(c1ccc(Cl)cc1)N1CCNC1=NC#N -US20030220402A1,2,COC(=O)c1ccccc1N.O=C(O)c1ccc(Oc2ccc3ccccc3c2)cc1>>COC(=O)c1ccccc1NC(=O)c1ccc(Oc2ccc3ccccc3c2)cc1 -US06919356B2,1,CCc1cc(NC(=O)NC[C@H]2CCCNC2)cc(-c2nnnn2C)c1.O=C(CCl)c1ccc(F)cc1>>CCc1cc(NC(=O)NC[C@@H]2CCCN(CC(=O)c3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 -US08293897B2,2,CCOC(=O)C1(C(=O)O)CC1.Nc1ccccc1>>CCOC(=O)C1(C(=O)Nc2ccccc2)CC1 -US06967196B1,6,CCOC(=O)CCCOc1ccccc1C(C)N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1>>CC(c1ccccc1OCCCC(=O)O)N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1 -US20080194629A1,2,COCCCCC1(CNC(=O)[C@H]2C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21.c1cc(CNC2CC2)ccn1>>COCCCCC1(CNC(=O)[C@H]2C[C@@H](C(=O)N(Cc3ccncc3)C3CC3)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21 -US20100069504A1,3,C=O.O=C(NC1CCc2ccccc2CC1=O)OCc1ccccc1>>C=C1C(=O)C(NC(=O)OCc2ccccc2)CCc2ccccc21 -US20090004185A1,3,CC(C)(C)/C=C/B(O)O.CN(C)c1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccc(I)cc2n1>>CN(C)c1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccc(/C=C/C(C)(C)C)cc2n1 -US20090221555A1,1,CCN1CC(=O)N(CC)c2cc(N)c(OC)cc2C1.COc1ccc(Nc2nc(Cl)ncc2Cl)c(-n2cccn2)c1>>CCN1CC(=O)N(CC)c2cc(Nc3ncc(Cl)c(Nc4ccc(OC)cc4-n4cccn4)n3)c(OC)cc2C1 -US07091222B2,1,BrC1CCC1.Cc1cc(C#Cc2c[nH]c(C)n2)ccn1>>Cc1cc(C#Cc2cn(C3CCC3)c(C)n2)ccn1 -US20070249670A1,1,COC(=O)[C@@H](N)[C@@H](C)O.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)[C@@H](NC(c1ccccc1)(c1ccccc1)c1ccccc1)[C@@H](C)O -US20070093483A1,2,NN.O=C(O)C(O)c1ccccc1Cl>>NNC(=O)C(O)c1ccccc1Cl -US06271251B1,6,CCOC(=O)CCCCn1c(C(=O)OCC)cc2c(Cl)cc(OCc3ccccc3)cc21>>CCOC(=O)CCCCn1c(C(=O)OCC)cc2c(Cl)cc(O)cc21 -US20050014787A1,6,COc1ccc(C#N)cc1S(=O)(=O)N(CCc1ccc(C(C)C)cc1)Cc1nccs1>>CC(C)c1ccc(CCN(Cc2nccs2)S(=O)(=O)c2cc(C#N)ccc2O)cc1 -US06150373,1,C1CNCCN1.CS(=O)(=O)OCCc1cccc(N2C(=O)N(c3ccc(Cl)cc3Cl)Cc3cnc(Nc4ccccc4)nc32)c1>>O=C1N(c2ccc(Cl)cc2Cl)Cc2cnc(Nc3ccccc3)nc2N1c1cccc(CCN2CCNCC2)c1 -US05624926,1,COc1cc2ncnc(N3CCC(n4c(=O)[nH]c5ccc([N+](=O)[O-])cc5c4=O)CC3)c2cc1OC.O=[N+]([O-])c1ccc(CBr)cc1>>COc1cc2ncnc(N3CCC(n4c(=O)c5cc([N+](=O)[O-])ccc5n(Cc5ccc([N+](=O)[O-])cc5)c4=O)CC3)c2cc1OC -US20100029619A1,2,CC(C)(CN)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1.O=C(O)Cc1cnc[nH]1>>CC(C)(CNC(=O)Cc1cnc[nH]1)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1 -US20090291950A1,1,COc1ccc2c(Cl)ncnc2c1OC1CCCC1.Nc1c(Cl)cccc1Cl>>COc1ccc2c(Nc3c(Cl)cccc3Cl)ncnc2c1OC1CCCC1 -US06989393B2,7,N#Cc1ccc(NC2CCN(CCC(c3ccccc3)c3ccccc3)CC2)c([N+](=O)[O-])c1>>N#Cc1ccc(NC2CCN(CCC(c3ccccc3)c3ccccc3)CC2)c(N)c1 -US20090054405A1,2,CC(=O)Nc1nc2ccc(-c3cccc(N)c3)cc2s1.COc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(S(=O)(=O)Nc2cccc(-c3ccc4nc(NC(C)=O)sc4c3)c2)cc1 -US04812164,2,CCCCOC(=O)Cl.CCOc1nc(C(F)(F)F)cc(=O)n1-c1cc(O)c(Cl)cc1F>>CCCCOC(=O)Oc1cc(-n2c(OCC)nc(C(F)(F)F)cc2=O)c(F)cc1Cl -US07414060B2,1,COCCn1ccc(NC(=O)c2nc(C)ccc2N)n1.Fc1ccnc(Cl)c1>>COCCn1ccc(NC(=O)c2nc(C)ccc2Nc2cc(F)ccn2)n1 -US06384051B1,7,CSc1cccc(Nc2c(C#N)cnc3ccc([N+](=O)[O-])cc23)c1>>CSc1cccc(Nc2c(C#N)cnc3ccc(N)cc23)c1 -US20140163025A1,7,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(C=CCC(C)(C)O)cn5)ccc(F)c43)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(CCCC(C)(C)O)cn5)ccc(F)c43)ccc21 -US20070082912A1,6,CCOC(=O)c1ccnc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)c1>>Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)ccn1 -US20020183285A1,6,COC1(c2ccc(C#C[Si](C)(C)C)cc2)CC1>>C#Cc1ccc(C2(OC)CC2)cc1 -US06262082B1,6,N#Cc1cc(NC(=O)c2ccccc2F)ccc1NC(=O)C(F)(F)F>>N#Cc1cc(NC(=O)c2ccccc2F)ccc1N -US07547710B2,2,CN.Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc3ccc(OCC(=O)O)cc23)cc1>>CNC(=O)COc1ccc2nc(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c3ccc(C)cc3)c2c1 -US20090111806A1,6,Cn1c(=O)c(C(=O)NCC(=O)OC(C)(C)C)c(O)c2cc(C#CC3CC3)cnc21>>Cn1c(=O)c(C(=O)NCC(=O)O)c(O)c2cc(C#CC3CC3)cnc21 -US08158790B2,2,CC1(C)O[C@@H](COCc2ccccc2)[C@H](CO)O1.CS(=O)(=O)Cl>>CC1(C)O[C@@H](COCc2ccccc2)[C@H](COS(C)(=O)=O)O1 -US20140213572A1,6,CC(C)(C)OC(=O)N1CC(c2nccnc2N2CCOCC2)C1>>c1cnc(N2CCOCC2)c(C2CNC2)n1 -US20070015758A1,2,C1CC1CNCC1CC1.CCCn1c(C(=O)O)c(CN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2ccccc21>>CCCn1c(C(=O)N(CC2CC2)CC2CC2)c(CN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2ccccc21 -US05939439,1,Brc1ccc(Oc2c[nH]cn2)cc1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Brc1ccc(Oc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1 -US07592477B2,1,CCCCCCCCOc1ccc(C=O)cc1.NCCc1ccccc1F>>CCCCCCCCOc1ccc(CNCCc2ccccc2F)cc1 -US20050020587A1,2,CC(=O)Cl.CC(C)(C)OC(=O)NC1CCNC1>>CC(=O)N1CCC(NC(=O)OC(C)(C)C)C1 -US20140357618A1,7,C=C(c1ncccc1F)c1nc2cc(Cl)nc(-c3cncc(Cl)c3)c2n1C[C@@H]1CC[C@@H](C)CC1>>CC(c1ncccc1F)c1nc2cc(Cl)nc(-c3cncc(Cl)c3)c2n1C[C@@H]1CC[C@@H](C)CC1 -US20040142843A1,1,CC[O-].Clc1cc(-c2ccccn2)nc(-c2ccccn2)c1>>CCOc1cc(-c2ccccn2)nc(-c2ccccn2)c1 -US20120088748A1,6,CC(C)(C)OC(=O)N1CCO[C@@H]([C@H](O)CO)[C@H](c2ccc(Cl)c(Cl)c2)C1>>OC[C@@H](O)[C@@H]1OCCNC[C@H]1c1ccc(Cl)c(Cl)c1 -US07659284B2,1,C1COCCN1.CC(C)(C)OC(=O)NCc1ccc(C=O)cc1>>CC(C)(C)OC(=O)NCc1ccc(CN2CCOCC2)cc1 -US05482966,9,COC1(c2cc(F)cc(S(=O)(=O)c3ccc4c(c3)CCC4=O)c2)CCOCC1.NO>>COC1(c2cc(F)cc(S(=O)(=O)c3ccc4c(c3)CC/C4=N\O)c2)CCOCC1 -US04348399,1,CCCCCCCCCCCCCCCCBr.N#Cc1ccc(N)cc1>>CCCCCCCCCCCCCCCCNc1ccc(C#N)cc1 -US06090802,2,COc1ccc(CS[C@H]2C[C@@H](C(=O)O)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1.O=C(C[C@H](O)[C@H](CC1CCCCC1)NC(=O)OCc1ccc([N+](=O)[O-])cc1)N[C@H]1CCNC1>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CC[C@H](NC(=O)C[C@H](O)[C@H](CC4CCCCC4)NC(=O)OCc4ccc([N+](=O)[O-])cc4)C3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1 -US08822453B2,7,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN3C(=O)C(=O)c4ccccc43)ccc21>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN3C(=O)Cc4ccccc43)ccc21 -US07572809B2,3,COc1ccc(B(O)O)cc1.Cc1cc(Nc2cc3ccccc3c(Cl)n2)n[nH]1>>COc1ccc(-c2nc(Nc3cc(C)[nH]n3)cc3ccccc23)cc1 -US08143271B2,3,O=C(c1cccc(O)c1F)c1c[nH]c2ncc(Br)cc12.OB(O)c1ccccc1>>O=C(c1cccc(O)c1F)c1c[nH]c2ncc(-c3ccccc3)cc12 -US07091211B2,7,COC(=O)C1(CCO[Si](C)(C)C(C)(C)C)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(CCO[Si](C)(C)C(C)(C)C)CC1 -US06897236B1,6,Cc1ccccc1C(=O)c1ccc(Nc2ccc(Br)cc2NC(=O)OCOC(=O)CCC(=O)OCc2ccccc2)cc1Cl>>Cc1ccccc1C(=O)c1ccc(Nc2ccc(Br)cc2NC(=O)OCOC(=O)CCC(=O)O)cc1Cl -US05760035,7,CN(C)CC=C1CCN(CCOc2ccccc2)CC1>>CN(C)CCC1CCN(CCOc2ccccc2)CC1 -US20060128633A1,2,COc1cc2c(c(OC)c1OC)-c1ccc(C(=O)O)cc1[C@@H](NC(C)=O)CC2.NCCCN1CCOCC1>>COc1cc2c(c(OC)c1OC)-c1ccc(C(=O)NCCCN3CCOCC3)cc1[C@@H](NC(C)=O)CC2 -US20070167474A1,6,CCCO[C@@]12CCC(=O)[C@]3(C)Oc4c(OC)ccc5c4[C@]13CCN(CC1CC1)[C@@H]2C5>>CCCO[C@@]12CCC(=O)[C@]3(C)Oc4c(O)ccc5c4[C@]13CCN(CC1CC1)[C@@H]2C5 -US06936608B2,7,O=[N+]([O-])c1ccc(F)c(-c2ncccc2F)c1>>Nc1ccc(F)c(-c2ncccc2F)c1 -US20080125409A1,2,COC(=O)C(N)C(=O)OC.O=C(Cl)c1ccccn1>>COC(=O)C(NC(=O)c1ccccn1)C(=O)OC -US20120322788A1,1,Cc1nc(C(=O)N2CCOC3(CCNCC3)C2)cs1.OCCc1ccc(CBr)cc1>>Cc1nc(C(=O)N2CCOC3(CCN(Cc4ccc(CCO)cc4)CC3)C2)cs1 -US04898874,2,CC(=O)N1CCNCC1.O=C(O)Cc1cc(Cl)cc2c(-c3ccccc3)onc12>>CC(=O)N1CCN(C(=O)Cc2cc(Cl)cc3c(-c4ccccc4)onc23)CC1 -US05163995,1,COc1cc2nc(S(=O)(=O)Nc3c(Cl)cccc3Cl)nn2c(Cl)n1.C[O-]>>COc1cc2nc(S(=O)(=O)Nc3c(Cl)cccc3Cl)nn2c(OC)n1 -US20100322882A1,2,O=C(O)C1CCCCC1.OCCc1ccccc1>>O=C(OCCc1ccccc1)C1CCCCC1 -US20070254894A1,2,Cc1cc(N)c2ncccc2c1C.O=S(=O)(Cl)c1ccccn1>>Cc1cc(NS(=O)(=O)c2ccccn2)c2ncccc2c1C -US20100004280A1,3,CCC(C)(C)Cc1cn(C(=O)OC(C)(C)C)c(C(Cc2ccc(Br)cc2)NC(=O)OCc2ccccc2)n1.Fc1ccc(Br)nc1>>CCC(C)(C)Cc1cn(C(=O)OC(C)(C)C)c(C(Cc2ccc(-c3ccc(F)cn3)cc2)NC(=O)OCc2ccccc2)n1 -US20040229880A1,1,CCOc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1F.CN1CCC(CCCO)CC1>>CCOc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1OCCCC1CCN(C)CC1 -US20070100141A1,2,CCC(CC)C(=O)O.COC(=O)C(c1ccccc1)N1CCN(c2ccc(N)cc2F)CC1>>CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)OC)c3ccccc3)CC2)c(F)c1 -US20150073011A1,7,CC(C)(C)OC(=O)N1CC(=O)C(I)=C[C@H]1CO[Si](C)(C)C(C)(C)C>>CC(C)(C)OC(=O)N1C[C@@H](O)C(I)=C[C@H]1CO[Si](C)(C)C(C)(C)C -US20100056515A1,1,CCC(CC)c1cccc2c1[nH]c(=O)n2Cc1ccc(OC)cc1.CN(C)CCCl>>CCC(CC)c1cccc2c1n(CCN(C)C)c(=O)n2Cc1ccc(OC)cc1 -US03939166,1,C#CCN.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c2[nH]c(C(F)(F)F)nc12>>C#CCNc1c(C(F)(F)F)cc([N+](=O)[O-])c2nc(C(F)(F)F)[nH]c12 -US20090312310A1,2,CC[C@@H]1CC[C@@H](C(=O)O)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1.CN1CCNCC1>>CC[C@@H]1CC[C@@H](C(=O)N2CCN(C)CC2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1 -US20050282863A1,1,ClCCN1CCCCC1.c1ccc2c(c1)SCCc1c-2[nH]c2ccccc12>>c1ccc2c(c1)SCCc1c-2n(CCN2CCCCC2)c2ccccc12 -US07550598B2,1,CC1=NNC(=O)/C1=C1/C=C(Cl)c2ccccc2N1.CCO>>CCOC1=C/C(=C2/C(=O)NN=C2C)Nc2ccccc21 -US08962664B2,2,CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](N)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.O=C(O)CC1CC1>>CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](NC(=O)CC2CC2)[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US20090069333A1,2,CCOC(=O)c1cnncc1N.O=C(Cl)Cc1c(F)cc(F)cc1F>>CCOC(=O)c1cnncc1NC(=O)Cc1c(F)cc(F)cc1F -US09156827B2,6,Cc1ccc2c(/C=C3\Oc4c(ccc(O)c4CN4CCN(C(=O)OC(C)(C)C)CC4)C3=O)c[nH]c2n1>>Cc1ccc2c(/C=C3\Oc4c(ccc(O)c4CN4CCNCC4)C3=O)c[nH]c2n1 -US20140323730A1,6,COc1ccc2nc(Cl)c(C=O)cc2c1>>O=Cc1cc2cc(O)ccc2nc1Cl -US06069149,1,CC(C)(C)OC(=O)NCCCn1cnc2c(Cl)nc3ccccc3c21.NCc1ccccc1>>CC(C)(C)OC(=O)NCCCn1cnc2c(NCc3ccccc3)nc3ccccc3c21 -US20150239884A1,1,COc1cc(OC2CCN(C)CC2)ccc1N.Cn1cc(-c2cccc3cnc(Cl)cc23)cn1>>COc1cc(OC2CCN(C)CC2)ccc1Nc1cc2c(-c3cnn(C)c3)cccc2cn1 -US03974284,1,N.O=C1C2c3ccccc3C3C1C3c1ccccc12>>NC1C2c3ccccc3C3C(c4ccccc42)C13 -US20070032488A1,4,C[Sn](C)(C)N=[N+]=[N-].Cc1nc(C)c(-c2ccc3cc(-c4c(CC(=O)N5CCOCC5)cc(C#N)cc4C4CCCCC4)ccc3n2)s1>>Cc1nc(C)c(-c2ccc3cc(-c4c(CC(=O)N5CCOCC5)cc(-c5nnn[nH]5)cc4C4CCCCC4)ccc3n2)s1 -US04605652,2,COc1cc2[nH]nnc2cc1C(=O)O.NC1CN2CCC1CC2>>COc1cc2[nH]nnc2cc1C(=O)NC1CN2CCC1CC2 -US06133259,2,CO.O=C(O)c1cc(I)ccc1O>>COC(=O)c1cc(I)ccc1O -US04604389,1,COc1cc2c(cc1OC)CC(=O)N(CCCCl)CC2.NCCNc1cc(Cl)c(N)c(Cl)c1>>COc1cc2c(cc1OC)CC(=O)N(CCCNCCNc1cc(Cl)c(N)c(Cl)c1)CC2 -US20120328569A1,3,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cccc(B4OC(C)(C)C(C)(C)O4)c3)cc12.Fc1cccc2sc(I)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cccc(-c4cc5c(F)cccc5s4)c3)cc12 -US04400550,7,CC/C=C\C#CCCCCCCCCCCl>>CC/C=C\C=C/CCCCCCCCCCl -US05077410,2,O=C(Cl)c1ccc(Cl)cc1Cl.O=C1CCNc2cc(Cl)ccc21>>O=C1CCN(C(=O)c2ccc(Cl)cc2Cl)c2cc(Cl)ccc21 -US04921950,1,COC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@H]1OS(C)(=O)=O.[N-]=[N+]=[N-]>>COC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@H]1N=[N+]=[N-] -US09050345B2,1,Clc1nc(Cl)c2c(-c3ccccc3)ccn2n1.NCc1ccccn1>>Clc1nc(NCc2ccccn2)c2c(-c3ccccc3)ccn2n1 -US05538966,1,CC(C)(C)NS(=O)(=O)c1cc2c(s1)S(=O)(=O)NCC2O.COCCBr>>COCCN1CC(O)c2cc(S(=O)(=O)NC(C)(C)C)sc2S1(=O)=O -US20130158075A1,6,COC(=O)C(C)(C)CCc1ncc(-c2ccc(NC(=O)N3CCCCC3)cc2)s1>>CC(C)(CCc1ncc(-c2ccc(NC(=O)N3CCCCC3)cc2)s1)C(=O)O -US20120202794A1,6,CCOC(=O)c1noc(-c2ccc(F)cc2)n1>>O=C(O)c1noc(-c2ccc(F)cc2)n1 -US04116956,2,NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1 -US05254565,7,O=[N+]([O-])c1cnc2ccc(C(F)(F)F)cc2c1-c1ccccc1>>Nc1cnc2ccc(C(F)(F)F)cc2c1-c1ccccc1 -US20110028501A1,4,COc1ccc(C(C=O)C=O)cc1.NN>>COc1ccc(-c2cn[nH]c2)cc1 -US05468879,3,C#C[Si](C)(C)C.CCCC1(CCC)CCSc2ccc(Br)cc21>>CCCC1(CCC)CCSc2ccc(C#C[Si](C)(C)C)cc21 -US07625948B2,7,CCOC(=O)C(COC(=O)Cc1ccc([N+](=O)[O-])c(C)c1)(C(=O)OCC)c1ccccc1>>CCOC(=O)C(COC(=O)Cc1ccc(N)c(C)c1)(C(=O)OCC)c1ccccc1 -US07964591B2,6,CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3c(C(F)(F)F)nnn3Cc3ccccc3)CC2)nn1>>CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3[nH]nnc3C(F)(F)F)CC2)nn1 -US20130310405A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c5cccc(/C=C/C(N)=O)c5nn4cc3-c3ccccc3)cc2)CCC1>>NC(=O)/C=C/c1cccc2c1nn1cc(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc21 -US04863920,3,C#Cc1ccc(Cl)cc1.CN1Cc2c(I)ncn2-c2ccc(F)cc2C1=O>>CN1Cc2c(C#Cc3ccc(Cl)cc3)ncn2-c2ccc(F)cc2C1=O -US04211783,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCCCCCCCCCBr>>Cc1ccc(S(=O)(=O)OCCCCCCCCCCCBr)cc1 -US20100331293A1,2,CC(C)(C)COC(=O)Cl.Cc1c(N2CCNCC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1>>Cc1c(N2CCN(C(=O)OCC(C)(C)C)CC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1 -US05656634,2,CCCCCCCCC1(C(=O)O)SCCCS1.COc1ccc2ncccc2c1N>>CCCCCCCCC1(C(=O)Nc2c(OC)ccc3ncccc23)SCCCS1 -US20100204276A1,2,COc1ccc2[nH]cc(CCNC(C)=O)c2c1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc2c(c1)c(CCNC(C)=O)cn2S(=O)(=O)c1ccc(C)cc1 -US08048909B2,8,O=S(=O)(c1cccs1)n1cc(CO)cc1-c1ccccc1>>O=Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cccs2)c1 -US20050261290A1,6,CC(C)(CN1CCC[C@@H]1C(=O)NC1C2CC3CC(C2)CC1C3)NC(=O)OC(C)(C)C>>CC(C)(N)CN1CCC[C@@H]1C(=O)NC1C2CC3CC(C2)CC1C3 -US20090137562A1,7,CN(Cc1cc(C=O)ccc1Oc1ccc(Cl)c(Cl)c1)C(=O)OC(C)(C)C>>CN(Cc1cc(CO)ccc1Oc1ccc(Cl)c(Cl)c1)C(=O)OC(C)(C)C -US20100317697A1,2,CCc1cccc(-c2c(F)cccc2C(O)(CCCNC(=O)OC)[C@@H]2CCCNC2)c1.CN(CC(O)CC(=O)[O-])S(=O)(=O)c1ccccc1[N+](=O)[O-]>>CCc1cccc(-c2c(F)cccc2C(O)(CCCNC(=O)OC)[C@@H]2CCCN(C(=O)CC(O)CN(C)S(=O)(=O)c3ccccc3[N+](=O)[O-])C2)c1 -US20150158863A1,2,COc1cnc([N+](=O)[O-])c(N)c1.O=C(Cl)CCl>>COc1cnc([N+](=O)[O-])c(NC(=O)CCl)c1 -US20070010526A1,2,CCCCNc1ccc(C(=O)O)cc1.COc1ccc(N2CCN(C)CC2)c2c1CCNC2>>CCCCNc1ccc(C(=O)N2CCc3c(OC)ccc(N4CCN(C)CC4)c3C2)cc1 -US20060063779A1,2,Nc1ccc(Cl)c(-c2ccccn2)c1.O=C(O)c1ccc(N2CCCC2=O)cc1Cl>>O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(N2CCCC2=O)cc1Cl -US20110015174A1,1,C=O.CCCCCc1ccc(S(=O)(=O)NC2(CC(=O)OCC)CCNC2)cc1>>CCCCCc1ccc(S(=O)(=O)NC2(CC(=O)OCC)CCN(C)C2)cc1 -US20130303533A1,1,Cc1cc(N)n[nH]1.Clc1nc(Cl)c2cnn(-c3ccccc3)c2n1>>Cc1cc(Nc2nc(Cl)nc3c2cnn3-c2ccccc2)n[nH]1 -US07557213B2,3,CON(C)C(=O)c1cn(Cc2cccc(C)n2)c2nc(C)c(C)cc2c1=O.COc1ccc([Mg+])cc1F>>COc1ccc(C(=O)c2cn(Cc3cccc(C)n3)c3nc(C)c(C)cc3c2=O)cc1F -US20110306722A1,2,Nc1ccc(C(=O)O)cc1.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc(C(=O)O)cc1)OCc1ccccc1 -US04180662,2,COC(=O)C1=C(O)c2sc(Br)cc2S(=O)(=O)N1C.Nc1ccccn1>>CN1C(C(=O)Nc2ccccn2)=C(O)c2sc(Br)cc2S1(=O)=O -US07803822B2,2,CCCc1c(C(=O)O)nnn1-c1ccc(C(=O)NCCCc2ccccc2)cc1.NC1CC1>>CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(C(=O)NCCCc2ccccc2)cc1 -US05405870,3,O=C(O)CCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1C[C@H]2CC3(C[C@H]2C1)OCCO3>>O=C(O)CCCC=C1C[C@H]2CC3(C[C@H]2C1)OCCO3 -US08440663B2,3,Brc1nc(Nc2ccc(N3CCOCC3)cc2)nc2[nH]ccc12.CC(=O)Nc1ccc(B(O)O)cc1>>CC(=O)Nc1ccc(-c2nc(Nc3ccc(N4CCOCC4)cc3)nc3[nH]ccc23)cc1 -US20050004094A1,6,Cn1cc(CCNC(=O)OCc2ccccc2)cn1>>Cn1cc(CCN)cn1 -US20110071178A1,1,BrCc1ccccc1.COC(=O)CO>>COC(=O)COCc1ccccc1 -US20110312974A1,2,CCNCc1cc(C(F)(F)F)ccc1-c1cc(C(F)(F)F)cc(CC(=O)OCC)n1.O=C(Cl)C1CCC1>>CCOC(=O)Cc1cc(C(F)(F)F)cc(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)C2CCC2)n1 -US06756380B1,1,CI.CSc1ncc(-c2ccccc2C)c(C(=O)NCc2cc(Cl)cc(Cl)c2)n1>>CSc1ncc(-c2ccccc2C)c(C(=O)N(C)Cc2cc(Cl)cc(Cl)c2)n1 -US20060106012A1,1,COc1cc(Cl)ccc1[N+](=O)[O-].Sc1ccccc1>>COc1cc(Sc2ccccc2)ccc1[N+](=O)[O-] -US05324839,3,CCCCc1nnc2ccccc2c1Cl.N#Cc1ccc(CBr)cc1>>CCCCc1nnc2ccccc2c1Cc1ccc(C#N)cc1 -US20020128467A1,9,O=c1[nH]c(=O)n([C@@H]2O[C@H](CI)[C@@H](O)[C@H]2O)cc1F>>C[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)[C@H](O)[C@@H]1O -US20080076924A1,9,O=C(Nc1cccc(F)c1)N1CCN(c2nc3ccccc3nc2Cl)C(c2ccccc2)C1>>O=C(Nc1cccc(F)c1)N1CCN(c2cnc3ccccc3n2)C(c2ccccc2)C1 -US08153652B2,2,CNCc1cn(C)c2ccccc12.O=C(O)/C=C/c1cnc2c(c1)OCCN2>>CN(Cc1cn(C)c2ccccc12)C(=O)/C=C/c1cnc2c(c1)OCCN2 -US08217177B2,6,COc1cnc2ccc(C(C)C(=O)OC(C)(C)C)cc2c1>>COc1cnc2ccc(C(C)C(=O)O)cc2c1 -US07964591B2,2,CC(C)CCNC(=O)c1ccc(N2CCNCC2)nn1.O=C(Cl)c1cc(Cl)ccc1C(F)(F)F>>CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3cc(Cl)ccc3C(F)(F)F)CC2)nn1 -US20090312288A1,2,CN(C)CCN.Cc1cnc2[nH]c3c(C)c(C(=O)O)cc(Cl)c3c2c1>>Cc1cnc2[nH]c3c(C)c(C(=O)NCCN(C)C)cc(Cl)c3c2c1 -US03940395,1,CCOC(=O)CNc1cc(Cl)nc(-c2ccccc2)n1.Sc1ccccc1>>CCOC(=O)CNc1cc(Sc2ccccc2)nc(-c2ccccc2)n1 -US06451819B2,1,O=C1CC(Cc2ccccc2)C1.O=S(=O)(c1ccc(O)cc1)C1CCNC1>>O=S(=O)(c1ccc(O)cc1)C1CCN([C@@H]2C[C@@H](Cc3ccccc3)C2)C1 -US20040122049A1,1,CCN(C(=O)Cc1ccc(F)cc1)C1CCNCC1.O=C(CCCl)c1ccc(F)cc1>>CCN(C(=O)Cc1ccc(F)cc1)C1CCN(CCC(=O)c2ccc(F)cc2)CC1 -US04186199,2,Nc1ccccc1N1CCc2ccccc21.O=C(Cl)c1ccccc1F>>O=C(Nc1ccccc1N1CCc2ccccc21)c1ccccc1F -US20040053963A1,1,NCC(CNc1cc(=O)c2ccccc2[nH]1)c1ccccc1.O=Cc1cn(Cc2ccccc2)c2ccccc12>>O=c1cc(NCC(CNCc2cn(Cc3ccccc3)c3ccccc23)c2ccccc2)[nH]c2ccccc12 -US08466181B2,2,CC(C)(N)CO.Cc1nnn(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)O)cn2)cn1>>Cc1nnn(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)NC(C)(C)CO)cn2)cn1 -US20140163077A1,9,N.O=C(O)c1ccc(-c2ccc(O)cc2)cc1>>NC(=O)c1ccc(-c2ccc(O)cc2)cc1 -US06376502B1,9,CCOC(=O)CCCNS(C)(=O)=O.[NH4+]>>CS(=O)(=O)NCCCC(N)=O -US06353006B1,1,BrC1CCCCCC1.NCCO>>OCCNC1CCCCCC1 -US06919331B2,6,COc1cc(=O)n(Cc2nc3cc(CNC(=O)OC(C)(C)C)ccc3n2CCCCO)c2ccccc12>>COc1cc(=O)n(Cc2nc3cc(CN)ccc3n2CCCCO)c2ccccc12 -US20140323468A1,8,CSCc1cncc(Br)c1.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cncc(Br)c1 -US08022062B2,2,NCCNc1c(Cl)ccc2c1CCN(C(=O)C(F)(F)F)CC2.O=C(Cl)c1ccccc1>>O=C(NCCNc1c(Cl)ccc2c1CCN(C(=O)C(F)(F)F)CC2)c1ccccc1 -US04656292,2,CC1=C(C)C(=O)N(CCCCCCO)C1=O.O=C(O)CCl>>CC1=C(C)C(=O)N(CCCCCCOC(=O)CCl)C1=O -US20090181968A1,1,O=C(NCC1CCC1)c1nc(O)ccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12.OCCBr>>O=C(NCC1CCC1)c1nc(OCCO)ccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12 -US04940710,1,C=O.CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(COC(C)C)C3)cc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)C(COC(C)C)C3)cc21 -US20050209274A1,1,COc1cc2oc(C(=O)NC3CCNCC3)cc(=O)c2cc1F.O=Cc1ccc2c(c1)OCCO2>>COc1cc2oc(C(=O)NC3CCN(Cc4ccc5c(c4)OCCO5)CC3)cc(=O)c2cc1F -US20090137577A1,1,CC(O)C1CCCCC1.O=Cc1ccc(O)cc1>>CC(Oc1ccc(C=O)cc1)C1CCCCC1 -US20080167368A1,2,CC(=O)Nc1[nH]cc(-c2ccc(N)cc2)c1C(N)=O.O=C=Nc1cc(F)cc(C(F)(F)F)c1>>CC(=O)Nc1[nH]cc(-c2ccc(NC(=O)Nc3cc(F)cc(C(F)(F)F)c3)cc2)c1C(N)=O -US20020188120A1,6,CCOC(=O)C1(S(=O)(=O)c2ccc(OC)cc2)CCCC1>>COc1ccc(S(=O)(=O)C2(C(=O)O)CCCC2)cc1 -US07317033B2,2,Cc1cscc1N=C=S.Nc1cc(Cl)c(Cl)cc1N>>Cc1cscc1NC(=S)Nc1cc(Cl)c(Cl)cc1N -US04933355,8,OCc1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=Cc1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US06495706B2,7,COC(=O)CCCCCCCCCCCCCC(=O)OC>>COC(=O)CCCCCCCCCCCCCCO -US20120208819A1,3,CN(C)Cc1nc(Br)cnc1N.C[C@H](NC(=O)c1cc(C#N)cnc1NCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)c1ccc(F)cc1>>C[C@H](NC(=O)c1cc(C#N)cnc1NCc1ccc(-c2cnc(N)c(CN(C)C)n2)cc1)c1ccc(F)cc1 -US03953397,2,O=C(Cl)c1c(Br)cc(Br)cc1Br.O=C1NC(=O)C2C1CCC(Br)C2Br>>O=C(c1c(Br)cc(Br)cc1Br)N1C(=O)C2CCC(Br)C(Br)C2C1=O -US07074813B2,2,NNC(=O)c1cccc(C(F)(F)F)c1.O=C(Cl)c1cccnc1Oc1ccccc1>>O=C(NNC(=O)c1cccnc1Oc1ccccc1)c1cccc(C(F)(F)F)c1 -US20110124875A1,6,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1N1CCOC1=O>>NCc1cc(Cl)ccc1N1CCOC1=O -US20090099162A2,1,CS(=O)(=O)NCCN1CC2CN(Cc3ccc(C#N)cc3)CC(C1)O2.N#Cc1ccc(CBr)cc1>>CS(=O)(=O)N(CCN1CC2CN(Cc3ccc(C#N)cc3)CC(C1)O2)Cc1ccc(C#N)cc1 -US05424333,1,CC(C)(C)NNC(=O)c1ccccn1.O=C(Cl)c1ccccc1[N+](=O)[O-]>>CC(C)(C)N(NC(=O)c1ccccn1)C(=O)c1ccccc1[N+](=O)[O-] -US20090099244A1,6,CCCC1(c2ccccc2)N=C(C)N(CC(=O)c2ccc(NC(C)=O)cc2F)C1=O>>CCCC1(c2ccccc2)N=C(C)N(CC(=O)c2ccc(N)cc2F)C1=O -US06900209B2,2,CS(=O)(=O)Cl.Cc1cc(-c2nnc3c4ccccc4c(OCc4ccc(CO)cn4)nn23)no1>>Cc1cc(-c2nnc3c4ccccc4c(OCc4ccc(COS(C)(=O)=O)cn4)nn23)no1 -US06723735B1,7,O=[N+]([O-])c1cccc(CN2CCOCC2)c1>>Nc1cccc(CN2CCOCC2)c1 -US20120329818A1,6,CN(C)C(=O)Oc1cccc(NC(=O)C2(Cc3ccccc3)CCN(C(=O)OC(C)(C)C)CC2)c1>>CN(C)C(=O)Oc1cccc(NC(=O)C2(Cc3ccccc3)CCNCC2)c1 -US08309734B2,2,O=C(O)c1ccncc1Br.c1ccc2c(c1)NCCO2>>O=C(c1ccncc1Br)N1CCOc2ccccc21 -US08680114B2,6,Cc1cn(S(=O)(=O)c2ccccc2)c2ncnc(N3CCN(C(=O)C(CNC(=O)OC(C)(C)C)c4ccc(Cl)cc4)CC3)c12>>Cc1cn(S(=O)(=O)c2ccccc2)c2ncnc(N3CCN(C(=O)C(CN)c4ccc(Cl)cc4)CC3)c12 -US07094789B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H]1CC[C@H](N)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1 -US06096781,1,COc1ccc(C(=O)CBr)cc1.Sc1ccccc1>>COc1ccc(C(=O)CSc2ccccc2)cc1 -US20130190487A1,6,O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(OCc3ccccc3)cc2)N1c1ccc(F)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(O)cc2)N1c1ccc(F)cc1 -US20070219228A1,1,CC(C)(O)CN.O=[N+]([O-])c1cnc2cc(Br)cnc2c1Cl>>CC(C)(O)CNc1c([N+](=O)[O-])cnc2cc(Br)cnc12 -US20090118296A1,6,COC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1>>O=C(O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1 -US07067534B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccc(C(F)(F)F)cc3)CC2)c1.Cc1ccc(NN)cc1>>Cc1ccc2[nH]c(-c3ccc(C(F)(F)F)cc3)c(CCCN3CCC(c4cccc(NC(=O)C(C)C)c4)CC3)c2c1 -US20060211678A1,7,Cn1cc([N+](=O)[O-])ccc1=O>>Cn1cc(N)ccc1=O -US07662988B2,2,C#CCc1c(F)c(F)c(CO)c(F)c1F.CC(C#N)=C[C@@H]1[C@@H](C(=O)O)C1(C)C>>C#CCc1c(F)c(F)c(COC(=O)[C@@H]2[C@@H](C=C(C)C#N)C2(C)C)c(F)c1F -US08440679B2,6,COC(=O)c1ccc(C)c(N2CCC3(CC2)OCCO3)c1>>Cc1ccc(C(=O)O)cc1N1CCC2(CC1)OCCO2 -US20030078261A1,3,C=C[Mg+].O=Cc1cc(Cl)cc(Cl)c1>>C=CC(O)c1cc(Cl)cc(Cl)c1 -US05220020,7,CCCCCCCCCC(=O)OCC>>CCCCCCCCCCO -US20130244995A1,2,COc1cc([C@@H](C)N[C@H]2CC[C@@H](c3ccc(CC(=O)O)cc3)C2)ccc1F.OC1CNC1>>COc1cc([C@@H](C)N[C@H]2CC[C@@H](c3ccc(CC(=O)N4CC(O)C4)cc3)C2)ccc1F -US20050020616A1,6,COC(=O)C(C)C(C#N)c1ccccc1>>CC(C(=O)O)C(C#N)c1ccccc1 -US20060009493A1,1,NNC(=O)Cc1ccc(O)c(Br)c1.O=C1Nc2ccccc2C1=O>>O=C(Cc1ccc(O)c(Br)c1)N/N=C1\C(=O)Nc2ccccc21 -US20100234421A1,2,CCSc1nc2ccccc2cc1N.O=C(O)CC1CCCCC1>>CCSc1nc2ccccc2cc1NC(=O)CC1CCCCC1 -US06803374B2,4,C[Sn](C)(C)N=[N+]=[N-].N#Cc1ccc2c(c1)nc(-c1ccc(OCc3ccccc3)cc1)n2C1CCCCC1>>c1ccc(COc2ccc(-c3nc4cc(-c5nnn[nH]5)ccc4n3C3CCCCC3)cc2)cc1 -US07625909B2,6,CC(C)(C)OC(=O)NC1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)NC1CNC1 -US07569582B2,6,CCN(CC)C(=O)N(C1CCCCC1)C1CC2CCC(C1)N2C(=O)[C@@H](Cc1ccc(Cl)cc1)NC1CCN(C(=O)OC(C)(C)C)CC1>>CCN(CC)C(=O)N(C1CCCCC1)C1CC2CCC(C1)N2C(=O)[C@@H](Cc1ccc(Cl)cc1)NC1CCNCC1 -US07579469B2,4,CC(C)(CC(=O)C(F)(F)F)c1cccc(C2(C)OCCO2)c1.C[S+](C)(C)=O>>CC(C)(CC1(C(F)(F)F)CO1)c1cccc(C2(C)OCCO2)c1 -US20110178063A1,2,CCO.CCn1nccc1C(=O)O>>CCOC(=O)c1ccnn1CC -US08686048B2,3,CCSc1cccc(B(O)O)c1.Nc1cc(F)c(Br)c(F)c1>>CCSc1cccc(-c2c(F)cc(N)cc2F)c1 -US07064123B1,2,CCC(N)C(O)c1nnc(-c2ccncc2)o1.O=C(O)C(CC(=O)N1CCCC1)CS(=O)(=O)Cc1ccccc1>>CCC(NC(=O)C(CC(=O)N1CCCC1)CS(=O)(=O)Cc1ccccc1)C(O)c1nnc(-c2ccncc2)o1 -US08426420B2,6,CCOC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)OCc2ccccc2)n(-c2ccccc2)n1>>CCOC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)O)n(-c2ccccc2)n1 -US07638648B2,6,COC(=O)C(C)c1ccc(C#Cc2cc(CN(C)C3CC3)c3c(c2)C(C)(C)CC(C)(C)O3)cc1>>CC(C(=O)O)c1ccc(C#Cc2cc(CN(C)C3CC3)c3c(c2)C(C)(C)CC(C)(C)O3)cc1 -US05998436,1,CCNC1CNC1.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(F)cc1F>>CCNC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4nc(N)c(F)cc4F)c3c2Cl)C1 -US20060287343A1,1,BrCc1ccc(Br)cc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(Br)cc2)CC1 -US07855288B2,2,CCOC(=O)c1cc2cnnc(Nc3cc(C(=O)O)ccc3OC)n2c1C.NC1CC1>>CCOC(=O)c1cc2cnnc(Nc3cc(C(=O)NC4CC4)ccc3OC)n2c1C -US06727264B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccccc3I)CC2)c1.NNc1ccccc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCc3c(-c4ccccc4I)[nH]c4ccccc34)CC2)c1 -US20080139558A1,2,Cc1cccc(C(=O)Cl)c1.O=c1cc(CNc2cccc(Cl)c2)c2cccc(F)c2[nH]1>>Cc1cccc(C(=O)N(Cc2cc(=O)[nH]c3c(F)cccc23)c2cccc(Cl)c2)c1 -US20100197939A1,1,BrCc1ccccc1.CC1(C)OC[C@H]([C@@H]2CNC(=O)C2)O1>>CC1(C)OC[C@H]([C@H]2CC(=O)N(Cc3ccccc3)C2)O1 -US20050054627A1,3,COc1ccccc1B(O)O.Oc1ncnc2ccc(Br)cc12>>COc1ccccc1-c1ccc2ncnc(O)c2c1 -US08791159B2,1,COC(=O)CCc1ccc(O)cc1.OCCCc1ccccc1>>COC(=O)CCc1ccc(OCCCc2ccccc2)cc1 -US04140775,1,CN1CCNCC1.O=[N+]([O-])c1ccc(CCl)cc1>>CN1CCN(Cc2ccc([N+](=O)[O-])cc2)CC1 -US04703048,2,COc1ccc(C=CC(=O)O)c(OC)c1.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>COc1ccc(C=CC(=O)N2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(OC)c1 -US06465507B2,3,O=C1Cc2cc(C(=O)O)ccc2N1.O=Cc1[nH]cc2c1CCOC2=O>>O=C1Nc2ccc(C(=O)O)cc2C1=Cc1[nH]cc2c1CCOC2=O -US04237160,7,O=C(O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C=C2>>O=S1(=O)c2ccccc2C=Cc2ccc(CO)cc21 -US20060058325A1,1,CC(C)(C)C(=O)OCCl.COc1cc2c(=O)[nH]cnc2cc1OCc1ccccc1>>COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCc1ccccc1 -US08901133B2,1,CN1CCNCC1.C[C@H](Nc1ncnc2[nH]cnc12)c1cc2cccc(Cl)c2c(Cl)n1>>C[C@H](Nc1ncnc2[nH]cnc12)c1cc2cccc(Cl)c2c(N2CCN(C)CC2)n1 -US07915411B2,7,COc1ccc(Sc2cc(C)cc([N+](=O)[O-])c2)cc1>>COc1ccc(Sc2cc(C)cc(N)c2)cc1 -US08361994B2,6,CC(C)(C)[Si](C)(C)OC1CCN(c2cccc(-n3ccnn3)c2)CC1>>OC1CCN(c2cccc(-n3ccnn3)c2)CC1 -US20100004128A1,1,CCOC(=O)c1n[nH]nc1C.FC(F)Cl>>CCOC(=O)c1nn(C(F)F)nc1C -US20150080373A1,1,CC(C)(C)OC(=O)NC1CCN(CCO)CC1.COc1ccc2ncc(Cl)nc2c1>>COc1ccc2ncc(OCCN3CCC(NC(=O)OC(C)(C)C)CC3)nc2c1 -US05120752,6,CCOC(=O)/C=C/c1cnc(Oc2ccc(Cl)cc2)s1>>O=C(O)/C=C/c1cnc(Oc2ccc(Cl)cc2)s1 -US08524699B2,1,FC1(F)CNC1.O=c1c(-c2cccnc2)c[nH]n1-c1cc(Cl)ncn1>>O=c1c(-c2cccnc2)c[nH]n1-c1cc(N2CC(F)(F)C2)ncn1 -US07820649B2,1,COc1cc(-c2nc3ccc(N4CCCNCC4)cc3c(=O)n2CC(=O)NC(C)C)ccc1F.OCCBr>>COc1cc(-c2nc3ccc(N4CCCN(CCO)CC4)cc3c(=O)n2CC(=O)NC(C)C)ccc1F -US20080027048A1,3,CC(C)COc1ccc(Br)cc1[N+](=O)[O-].N#Cc1ccc(Br)s1>>CC(C)COc1ccc(-c2ccc(C#N)s2)cc1[N+](=O)[O-] -US20130345188A1,6,CC=C1C(=O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(=O)OC)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12>>C/C=C1\C(=O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12 -US20070287725A1,7,O=[N+]([O-])c1cnc2cccnc2c1NCc1cc(-c2ccc(F)cc2)no1>>Nc1cnc2cccnc2c1NCc1cc(-c2ccc(F)cc2)no1 -US20150087626A1,6,COC(=O)c1ccc(C2(NC(=O)C3CC4(CCN3Cc3cccc(C(F)(F)F)c3)CC4)CC2)cc1>>O=C(O)c1ccc(C2(NC(=O)C3CC4(CCN3Cc3cccc(C(F)(F)F)c3)CC4)CC2)cc1 -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1COC(=O)NC1CCCC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4COC(=O)NC4CCCC4)cc3)cc2)CC1 -US20140142185A1,7,CC(=O)c1ccc(C)c([N+](=O)[O-])c1>>CC(=O)c1ccc(C)c(N)c1 -US20150105403A1,6,NC(/C=C/c1ccc(/C(=C(\c2ccccc2)C2CCC2)c2ccc3c(c2)c(F)nn3C2CCCCO2)cc1)=N\O>>NC(/C=C/c1ccc(/C(=C(\c2ccccc2)C2CCC2)c2ccc3[nH]nc(F)c3c2)cc1)=N\O -US20050124692A1,6,COc1cc(Cl)cc2c1CCC2>>Oc1cc(Cl)cc2c1CCC2 -US09139528B2,3,COC(=O)C1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Oc1ccc2nc(Cl)ccc2c1>>COC(=O)C1CC=C(c2ccc3cc(O)ccc3n2)CC1 -US06632816B1,2,CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](N)Cc1ccc2ccccc2c1)S(=O)(=O)c1ccc(N)cc1.O=C(Cl)N1CCOCC1>>CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)N1CCOCC1)S(=O)(=O)c1ccc(N)cc1 -US08377895B2,3,C=O.O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12.OC1CCNC1>>O=c1cc(-c2ccccc2)oc2c(CN3CCC(O)C3)c(O)c(O)c(O)c12 -US20150150845A1,7,CN1CCC(Oc2cc3c(cc2[N+](=O)[O-])C(=O)c2c([nH]c4cc(C#N)ccc24)C3(C)C)CC1>>CN1CCC(Oc2cc3c(cc2N)C(=O)c2c([nH]c4cc(C#N)ccc24)C3(C)C)CC1 -US07855292B2,2,COC(=O)[C@@H](N)Cc1ccc(Cl)c(Cl)c1.O=C(O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12>>COC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12 -US20050261331A1,4,COc1ccc(CC(=O)c2ccccc2)cc1.NNc1ccc(Br)cn1>>COc1ccc(-c2c(-c3ccccc3)[nH]c3ncc(Br)cc23)cc1 -US04786310,2,C=CCn1c(=O)sc2cc(F)c(NC(=O)N3CCCCN3C(=O)OCC)cc21>>C=CCn1c(=O)sc2cc(F)c(-n3c(=O)n4n(c3=O)CCCC4)cc21 -US20070099915A1,7,COC(=O)c1ncc2c(ccn2Cc2ccc(F)cc2)c1C#CCN(OC(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>COC(=O)c1ncc2c(ccn2Cc2ccc(F)cc2)c1CCCN(OC(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US20050137243A1,1,ClCCN1CCCC1.O=[N+]([O-])c1ccc2[nH]nc(Cl)c2c1>>O=[N+]([O-])c1ccc2c(c1)c(Cl)nn2CCN1CCCC1 -US20130237537A1,2,Cc1cccc(N)c1.O=C(O)c1ccnc(Br)c1>>Cc1cccc(NC(=O)c2ccnc(Br)c2)c1 -US08648074B2,7,CC(C)(C)OC(=O)N1CCN2CC[C@@H](OC(=O)c3ccccc3)[C@@H]2C1>>CC(C)(C)OC(=O)N1CCN2CC[C@@H](O)[C@@H]2C1 -US09139534B2,6,CCOC(=O)c1cnc(SC)nc1N[C@@H]1CCC[C@H](OC)C1>>CO[C@H]1CCC[C@@H](Nc2nc(SC)ncc2C(=O)O)C1 -US06911445B2,6,c1ccc(CN[C@H]2CC[C@H](c3c[nH]c4ccccc34)C2)cc1>>N[C@H]1CC[C@H](c2c[nH]c3ccccc23)C1 -US20100081643A1,6,COC(=O)c1cc(Oc2nc3cc(-c4ccc5ccccc5c4)c(Cl)cc3[nH]2)ccc1C>>Cc1ccc(Oc2nc3cc(-c4ccc5ccccc5c4)c(Cl)cc3[nH]2)cc1C(=O)O -US20140200225A1,1,CCOC(=O)c1cc(O)cc(Oc2c(F)cc(CNC(=O)OC(C)(C)C)cc2F)c1.N#Cc1ccc(F)cc1>>CCOC(=O)c1cc(Oc2ccc(C#N)cc2)cc(Oc2c(F)cc(CNC(=O)OC(C)(C)C)cc2F)c1 -US20070254929A1,7,O=C(O)[C@H](CCC(F)(F)F)NS(=O)(=O)c1ccc(Cl)s1>>O=S(=O)(NC(CO)CCC(F)(F)F)c1ccc(Cl)s1 -US20050059713A1,2,COC(=O)[C@@H](N)Cc1ccc(-c2ccccc2)cc1.O=C(O)c1cnc(COc2cccc(OC(F)(F)F)c2)cn1>>COC(=O)[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1cnc(COc2cccc(OC(F)(F)F)c2)cn1 -US20100016401A1,2,Nc1nc(-c2ccccc2C(=O)O)cs1.O=C(NC[C@H]1NC[C@H]2C[C@H]21)c1cccc2occc12>>Nc1nc(-c2ccccc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)c2cccc3occc23)cs1 -US20100273786A1,6,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)N3CC[C@H](F)C3)c2C1)Cc1cc(F)c(F)cc1F>>N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)N3CC[C@H](F)C3)c2C1)Cc1cc(F)c(F)cc1F -US20030109516A1,1,CS(=O)(=O)OCCCNC(=O)C(F)(F)F.Clc1ccc(C2=CCNCC2)cc1>>O=C(NCCCN1CC=C(c2ccc(Cl)cc2)CC1)C(F)(F)F -US05015661,3,C#CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1.Ic1ccccc1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C#Cc1ccccc1)O2 -US07279470B2,2,CN(C(=O)Cl)c1ccccc1.CS(=O)(=O)c1ccc(O)cc1>>CN(C(=O)Oc1ccc(S(C)(=O)=O)cc1)c1ccccc1 -US04835275,7,Nc1c2c(nc3cc(F)ccc13)CCCC2=O>>Nc1c2c(nc3cc(F)ccc13)CCCC2O -US20150057265A1,2,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2N)C1.CCc1cnc2c(C(=O)O)c(NC(=O)OC(C)(C)C)oc2c1>>CCc1cnc2c(C(=O)Nc3cnccc3N3CCC[C@H](NC(=O)OC(C)(C)C)C3)c(NC(=O)OC(C)(C)C)oc2c1 -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(-c2ccc(F)cc2)c1=O.CN>>CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(-c2ccc(F)cc2)c1=O -US20150025068A1,3,COC(=O)c1ccc(NS(=O)(=O)c2cnc(Cl)c(Br)c2)cc1O.OB(O)c1cccc(F)c1>>COC(=O)c1ccc(NS(=O)(=O)c2cnc(Cl)c(-c3cccc(F)c3)c2)cc1O -US20030153752A1,3,CC1(C)OB(c2ccc(CC(=O)Nc3ccccc3)cc2)OC1(C)C.CN1CCN([C@@H]2CC[C@H](n3cc(I)c4c(Cl)ncnc43)CC2)CC1>>CN1CCN(C2CCC(n3cc(-c4ccc(CC(=O)Nc5ccccc5)cc4)c4c(Cl)ncnc43)CC2)CC1 -US20070191603A1,2,COC(=O)c1ccc(NC(=O)c2ccc3c(c2)NCCO3)nc1.COc1ccc(Cl)cc1S(=O)(=O)Cl>>COC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(Cl)ccc2OC)CCO3)nc1 -US20140194408A1,7,COCc1cc(Nc2cc(-c3ccnc(N4CCc5c(cc6n5CCCC6)C4=O)c3C=O)cn(C)c2=O)nn1C>>COCc1cc(Nc2cc(-c3ccnc(N4CCc5c(cc6n5CCCC6)C4=O)c3CO)cn(C)c2=O)nn1C -US20090318431A1,7,CN1C(=O)OCc2c(F)c([N+](=O)[O-])cc(F)c21>>CN1C(=O)OCc2c(F)c(N)cc(F)c21 -US20110178060A1,2,CC(C)(O)C(=O)O.CN(C(=O)N(C)[C@@H]1CN(C(=O)[C@@H]2CC[C@@H](N)CC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN(C(=O)N(C)[C@@H]1CN(C(=O)[C@@H]2CC[C@@H](NC(=O)C(C)(C)O)CC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US08952010B2,1,COc1ccc2ncc(=O)n(CC=O)c2c1.NC[C@H]1CC(=O)N(c2ccc3c(c2)NC(=O)CO3)C1>>COc1ccc2ncc(=O)n(CCNC[C@H]3CC(=O)N(c4ccc5c(c4)NC(=O)CO5)C3)c2c1 -US20090149466A1,1,O=Cc1cc(F)cc(F)c1O.O=c1cc(N2CCNCC2)nc[nH]1>>O=c1cc(N2CCN(Cc3cc(F)cc(F)c3O)CC2)nc[nH]1 -US20120010241A1,1,CC(C)(O)CN.COC(=O)c1cccc2c1c(C)nn2-c1ccc(C#N)c(Br)c1>>COC(=O)c1cccc2c1c(C)nn2-c1ccc(C#N)c(NCC(C)(C)O)c1 -US20140114068A1,7,CCCCc1cn(C23C(=O)c4c([N+](=O)[O-])cccc4C2(O)Oc2cc(C(C)C)ccc23)nn1>>CCCCc1cn(C23C(=O)c4c(N)cccc4C2(O)Oc2cc(C(C)C)ccc23)nn1 -US20150210687A1,6,COC(=O)c1ccc(-c2cn(Cc3c(Cl)cccc3C(F)(F)F)c3cccnc23)c(F)c1>>O=C(O)c1ccc(-c2cn(Cc3c(Cl)cccc3C(F)(F)F)c3cccnc23)c(F)c1 -US20110009619A1,6,CC(C)(C)OC(=O)NNC(=O)C(CCCCl)c1cc(F)c(F)c(F)c1>>NNC(=O)C(CCCCl)c1cc(F)c(F)c(F)c1 -US20140213586A1,1,COc1cc(N)cc(OC)c1.O=C(c1c[nH]c2ccc(CCCO)cc12)C(Br)c1ccc(F)cc1>>COc1cc(NC(C(=O)c2c[nH]c3ccc(CCCO)cc23)c2ccc(F)cc2)cc(OC)c1 -US20150175623A1,3,CCOC(=O)[C@H](Cc1ccccc1OC)Oc1ncnc2sc(CC)c(I)c12.Cc1c(B2OC(C)(C)C(C)(C)O2)ccc(O)c1Cl>>CCOC(=O)[C@H](Cc1ccccc1OC)Oc1ncnc2sc(CC)c(-c3ccc(O)c(Cl)c3C)c12 -US07342012B2,9,[N-]=[N+]=N[C@@H]1CN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)[C@@]2(Cc2ccc(Br)cc2)C1>>N[C@@H]1CN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)[C@@]2(Cc2ccc(Br)cc2)C1 -US20090137773A1,2,NCC(=O)O.O=C(Cl)CCC(F)(C(F)(F)F)C(F)(F)F>>O=C(O)CNC(=O)CCC(F)(C(F)(F)F)C(F)(F)F -US06677460B1,7,CCOC(=O)c1cc(Cl)c2c(c1C)C(=O)CCS2>>CCOC(=O)c1cc(Cl)c2c(c1C)C(O)CCS2 -US04525589,2,CN.O=S(=O)(Cl)c1cccc2cnccc12>>CNS(=O)(=O)c1cccc2cnccc12 -US20110130445A1,6,CCCC(CC(=O)OC)c1ccc(Cl)c(NC(=O)[C@H](c2ccc(Cl)cc2)[C@@H](C)C(F)(F)F)c1>>CCCC(CC(=O)O)c1ccc(Cl)c(NC(=O)[C@H](c2ccc(Cl)cc2)[C@@H](C)C(F)(F)F)c1 -US20140051679A1,3,CC(C)(O)C1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccsc1)N1CCC1>>CC(C)(O)C1CCN(c2ccc(-c3n[nH]c4ccc(NC(=O)C(c5ccsc5)N5CCC5)cc34)cc2)CC1 -US20090062251A1,6,CC(=O)OC[C@H](CCC(=O)OCc1ccccc1)N(C)C(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1>>CC(=O)OC[C@H](CCC(=O)O)N(C)C(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1 -US20080076771A1,1,COc1ccc(CCl)cc1.CSc1nsc(NC(=O)OC(C)(C)C)n1>>COc1ccc(CN(C(=O)OC(C)(C)C)c2nc(SC)ns2)cc1 -US20130225646A1,2,CC(C)(C)OC(=O)NC(CN)c1ccccc1C(F)(F)F.O=C(O)Cn1nc(-c2ccc(Cl)s2)n(Cc2ccccc2F)c1=O>>CC(C)(C)OC(=O)NC(CNC(=O)Cn1nc(-c2ccc(Cl)s2)n(Cc2ccccc2F)c1=O)c1ccccc1C(F)(F)F -US07122550B2,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O.Clc1cncc(NCc2ccco2)n1>>COc1cc(-c2cncc(NCc3ccco3)n2)ccc1O -US20120115714A1,3,Ic1ccccc1.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2ccccc2)cc1 -US06908916B2,6,CC(=O)OCC(=O)NC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1>>O=C(CO)NC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 -US20040220177A1,6,CC(C)(C)OC(=O)N1CC=C(c2c[nH]c3ccc(Nc4ncc(Br)c(NCc5ccc(C(F)(F)F)cc5)n4)cc23)CC1>>FC(F)(F)c1ccc(CNc2nc(Nc3ccc4[nH]cc(C5=CCNCC5)c4c3)ncc2Br)cc1 -US20110009454A1,1,CCCc1ccc(O)cc1.N#Cc1cccc(F)c1>>CCCc1ccc(Oc2cccc(C#N)c2)cc1 -US20150210681A1,6,CCOC(=O)C1(c2ccc(-c3ccc(CCCOC)cc3)cc2)CC1>>COCCCc1ccc(-c2ccc(C3(C(=O)O)CC3)cc2)cc1 -US07229987B2,2,CCOC(=O)Cl.COC(=O)c1ccc(N)cc1>>CCOC(=O)Nc1ccc(C(=O)OC)cc1 -US08293902B2,2,COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OC[C@@H]1CCCN1.CS(=O)(=O)Cl>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OC[C@@H]1CCCN1S(C)(=O)=O -US08030354B2,2,CC1(C)CCC=C1c1cc(C(=O)O)ccc1-c1cc(O)ccc1F.CO>>COC(=O)c1ccc(-c2cc(O)ccc2F)c(C2=CCCC2(C)C)c1 -US20120028931A1,1,CCOP(=O)(CC(N)=NOC(=O)c1cccc(Cl)c1)OCC>>CCOP(=O)(Cc1noc(-c2cccc(Cl)c2)n1)OCC -US20100317624A1,6,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(c2)c(=O)c(C(=O)OCC)cn3C(COC)COC)cn1>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(c2)c(=O)c(C(=O)O)cn3C(COC)COC)cn1 -US08471005B2,1,COc1cc(C2CCN(CC(N)=O)CC2)ccc1N.Cc1cc(-c2ccccc2N(C)S(C)(=O)=O)n2nc(O)ncc12>>COc1cc(C2CCN(CC(N)=O)CC2)ccc1Nc1ncc2c(C)cc(-c3ccccc3N(C)S(C)(=O)=O)n2n1 -US04313959,9,NO.O=C1CCC(O)(c2ccccc2Cc2ccccc2)CC1>>ON=C1CCC(O)(c2ccccc2Cc2ccccc2)CC1 -US06479519B1,2,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.COC(=O)C[C@@H](N)c1ccc(NC(=O)Cc2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)cc1>>COC(=O)C[C@@H](NS(=O)(=O)c1cccc2c(N(C)C)cccc12)c1ccc(NC(=O)Cc2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)cc1 -US08536209B2,8,CC(O)c1cc(C(C)(C)O[SiH2]C(C)(C)C)on1>>CC(=O)c1cc(C(C)(C)O[SiH2]C(C)(C)C)on1 -US20070161626A1,6,CC(C)(C)OC(=O)Nc1ccc(-c2ccc3c(-c4sccc4C(N)=O)n[nH]c3c2F)cc1F>>NC(=O)c1ccsc1-c1n[nH]c2c(F)c(-c3ccc(N)c(F)c3)ccc12 -US08158810B2,1,CC(C)(C)OP(=O)(OCCl)OC(C)(C)C.O=c1c(-c2ccc(O)cc2)coc2cc(OCc3coc(-c4cc(F)cc(C(F)(F)F)c4)n3)ccc12>>CC(C)(C)OP(=O)(OCOc1ccc(-c2coc3cc(OCc4coc(-c5cc(F)cc(C(F)(F)F)c5)n4)ccc3c2=O)cc1)OC(C)(C)C -US20150152065A1,1,Cc1ccc(C)c(CBr)c1.c1ccc2[nH]cnc2c1>>Cc1ccc(C)c(Cn2cnc3ccccc32)c1 -US04806685,1,CN(C)CCO.COc1ccc(C(=C(c2ccccc2)C(F)(F)F)c2ccc(F)cc2)cc1>>COc1ccc(C(=C(c2ccccc2)C(F)(F)F)c2ccc(OCCN(C)C)cc2)cc1 -US07709471B2,1,CO.O=C(O)c1cc(F)c([N+](=O)[O-])cc1F>>COc1cc(C(=O)O)c(F)cc1[N+](=O)[O-] -US08044069B2,2,FC(F)(F)c1ccc2c(c1)CNC2.O=C(O)CCCN1CCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CCCN1CCC(c2ccccc2)(c2ccccc2)C1=O)N1Cc2ccc(C(F)(F)F)cc2C1 -US20090191420A1,2,CC1CCC(C(C)C)C(O)C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC2CC(C)CCC2C(C)C)cc1 -US20150133457A1,7,COc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1Oc1cccc([N+](=O)[O-])c1>>COc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1Oc1cccc(N)c1 -US06887889B2,3,N#Cc1cccc(B(O)O)c1.O=C(Cc1cc(F)cc(F)c1)NCC1(c2ccc(I)cc2)CCN(CC2CC2)CC1>>N#Cc1cccc(-c2ccc(C3(CNC(=O)Cc4cc(F)cc(F)c4)CCN(CC4CC4)CC3)cc2)c1 -US20100278833A1,2,CC(Oc1cc(-n2cnc3cc(CO)ncc32)sc1C(N)=O)c1ccccc1F.CS(=O)(=O)Cl>>CC(Oc1cc(-n2cnc3cc(COS(C)(=O)=O)ncc32)sc1C(N)=O)c1ccccc1F -US20040176602A1,3,Brc1ccc(CN2CCOCC2)nc1.Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(Br)ccc23)cc1Cl>>Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCOCC5)nc4)ccc23)cc1Cl -US07709491B2,6,COC(=O)CC1c2cccc(F)c2N=C(c2ccc(-c3ccc(F)cc3)cc2)N1c1cc(C(F)(F)F)ccc1OC>>COc1ccc(C(F)(F)F)cc1N1C(c2ccc(-c3ccc(F)cc3)cc2)=Nc2c(F)cccc2C1CC(=O)O -US06028201,1,CCCCCN.N#Cc1ccc(Cn2cncc2C=O)cc1>>CCCCCNCc1cncn1Cc1ccc(C#N)cc1 -US07632829B2,1,CI.COC(=O)NC1CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1 -US04533670,1,Cc1ncc[nH]1.O=C(CBr)c1ccc2c(c1)Cc1ccccc1-2>>Cc1nccn1CC(=O)c1ccc2c(c1)Cc1ccccc1-2 -US07262302B2,4,N#CCC(N)=S.O=C1c2ccc(Cl)cc2Sc2ccccc2C1Br>>N#CCc1nc2c(s1)-c1ccccc1Sc1cc(Cl)ccc1-2 -US20130072492A1,10,COC(=O)C(C)c1coc(C)n1.O=C1CCC(=O)N1Br>>COC(=O)C(C)(Br)c1coc(C)n1 -US04937239,8,OCC1=CN2CCC1CC2>>O=CC1=CN2CCC1CC2 -US20140113910A1,6,CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NC5CCN(C(=O)OC(C)(C)C)CC5)c([N+](=O)[O-])c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1>>CC1(C)CCC(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NC5CCNCC5)c([N+](=O)[O-])c4)c(Oc4cnc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1 -US20090253680A1,2,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc(C)c1OCc1ccccc1.c1ccc(CN2CCNCC2)cc1>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(Cc3ccccc3)CC2)cc(C)c1OCc1ccccc1 -US07727988B2,1,COC(CCBr)OC.O=c1[nH]cc(-c2cnccn2)c(=O)[nH]1>>COC(CCn1cc(-c2cnccn2)c(=O)[nH]c1=O)OC -US20110015175A1,1,COc1cc(Nc2n[nH]c(C(CCCCCl)c3ccc(OC(F)(F)F)cc3)n2)c(F)cc1-n1cnc(C)n1>>COc1cc(Nc2nc3n(n2)CCCCC3c2ccc(OC(F)(F)F)cc2)c(F)cc1-n1cnc(C)n1 -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12.NC(=O)COc1ccc(C=O)cc1>>NC(=O)COc1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US04167515,1,CC1(C)CC(c2cccc3ccccc23)c2ccc(O)cc2O1.CN(C)CCCl>>CN(C)CCOc1ccc2c(c1)OC(C)(C)CC2c1cccc2ccccc12 -US06127380,1,OCCCl.Oc1cccc2nc[nH]c12>>ClCCOc1cccc2nc[nH]c12 -US20130338106A1,1,CC1(C)CC(=O)c2c(SC3CCCC3)sc(-c3cc[nH]n3)c2C1.CCCC(=O)Cl>>CCCC(=O)n1ccc(-c2sc(SC3CCCC3)c3c2CC(C)(C)CC3=O)n1 -US08268859B2,6,C#CCC(CC(C)(C)c1ccccc1C(N)=O)(O[Si](C)(C)C)C(F)(F)F>>C#CCC(O)(CC(C)(C)c1ccccc1C(N)=O)C(F)(F)F -US20050234131A1,3,C#CC(O)c1ccc2c(c1)C(C)(C)CC=C2c1ccc(OCc2ccccc2)cc1.O=C(O)c1ccc(I)cc1>>CC1(C)CC=C(c2ccc(OCc3ccccc3)cc2)c2ccc(C(O)C#Cc3ccc(C(=O)O)cc3)cc21 -US20080188521A1,4,C#CC(CC)(OC(=O)c1ccc([N+](=O)[O-])cc1)C(F)(F)F.N#Cc1cc(-c2ccccc2)c2ccc(CN=[N+]=[N-])cc2n1>>CC[C@](OC(=O)c1ccc([N+](=O)[O-])cc1)(c1cn(Cc2ccc3c(-c4ccccc4)cc(C#N)nc3c2)nn1)C(F)(F)F -US20150073011A1,1,COc1ccc(COc2cnc(CO)cc2OCc2ccc(OC)cc2)cc1.O=C1NC(=O)c2ccccc21>>COc1ccc(COc2cnc(CN3C(=O)c4ccccc4C3=O)cc2OCc2ccc(OC)cc2)cc1 -US06245778B1,2,COc1ccc(C(=O)O)cc1Br.Nc1cnc2c(c1)CN(Cc1ccccc1)CC2>>COc1ccc(C(=O)Nc2cnc3c(c2)CN(Cc2ccccc2)CC3)cc1Br -US20120095034A1,2,Cc1nc(C(=O)O)c(-c2ccccc2)s1.Fc1ccc2nc(C[C@@H]3CCCCN3)c(Cl)n2c1>>Cc1nc(C(=O)N2CCCC[C@H]2Cc2nc3ccc(F)cn3c2Cl)c(-c2ccccc2)s1 -US07635715B2,6,CCOC(=O)C1(c2c(Cl)cccc2C#CC(OCC)(OCC)OCC)CCOCC1>>CCOC(=O)C#Cc1cccc(Cl)c1C1(C(=O)OCC)CCOCC1 -US20100087437A1,2,O=C(c1ccc(NCc2ccc(Cl)cc2)cc1)N1CCN(c2ccccc2)CC1.O=S(=O)(Cl)c1ccccc1>>O=C(c1ccc(N(Cc2ccc(Cl)cc2)S(=O)(=O)c2ccccc2)cc1)N1CCN(c2ccccc2)CC1 -US20040092533A1,3,Brc1cccc(Br)n1.[Zn+]C1CCCC1>>Brc1cccc(C2CCCC2)n1 -US20080293771A1,1,CCBr.Cc1nc2ccccc2n1-c1ccc(C(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1>>CCN(C(=O)c1ccc(-n2c(C)nc3ccccc32)cc1)[C@@H]1CCN(C(=O)OC(C)(C)C)C1 -US20030176481A1,1,CI.O=Cc1ccc(O)c(Cl)c1>>COc1ccc(C=O)cc1Cl -US20110009381A1,2,Nc1ccccc1-c1nc2cccnc2s1.O=C(O)c1cc(O)cc(-c2ccccc2)n1>>O=C(Nc1ccccc1-c1nc2cccnc2s1)c1cc(O)cc(-c2ccccc2)n1 -US20060135576A1,2,CS(=O)(=O)Cl.Nc1cc(C(=O)NC2CC2)ccc1F>>CS(=O)(=O)Nc1cc(C(=O)NC2CC2)ccc1F -US08637501B2,1,Cn1c2c(c3ccc(Br)cc31)CN(C(=O)OC(C)(C)C)CCC2.O=c1cc(OCc2ccc(Cl)cc2Cl)cc[nH]1>>Cn1c2c(c3ccc(-n4ccc(OCc5ccc(Cl)cc5Cl)cc4=O)cc31)CN(C(=O)OC(C)(C)C)CCC2 -US07749530B2,1,Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)c2)n(C)n1.Nc1ccc(CO)cc1>>Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CNc3ccc(CO)cc3)c2)n(C)n1 -US20040063720A1,1,C1CN(CCN2CCOCC2)CCN1.Cc1nc(N)cc(Cl)n1>>Cc1nc(N)cc(N2CCN(CCN3CCOCC3)CC2)n1 -US20100256143A1,1,C1COCCN1.CSc1nc(Cl)cc(Cl)n1>>CSc1nc(Cl)cc(N2CCOCC2)n1 -US04861880,9,CN(C)C=C1C(=O)Nc2ccc(Cl)cc21>>CN(C)C=C1C(=O)Nc2ccccc21 -US20080200461A1,2,COc1cc2c(=O)n(CCCO)c(SCc3cc(C)cc(C)c3)nc2c(OC)c1OC.CS(=O)(=O)Cl>>COc1cc2c(=O)n(CCCOS(C)(=O)=O)c(SCc3cc(C)cc(C)c3)nc2c(OC)c1OC -US20050054699A1,2,CCN.O=C(O)CCc1ccc(F)cc1C[C@@H]1[C@H](c2nc(C(=O)NCCCCC3CCCCC3)co2)C2CC[C@@H]1O2>>CCNC(=O)CCc1ccc(F)cc1CC1C2CCC(O2)C1c1nc(C(=O)NCCCCC2CCCCC2)co1 -US06919331B2,9,CC(C)CCn1c(CO)nc2ccc(Br)cc21.[C-]#N>>CC(C)CCn1c(CO)nc2ccc(C#N)cc21 -US20100093814A1,4,CC1(C)OC(C)(C)C(Br)C1=O.NC(N)=S>>CC1(C)OC(C)(C)c2sc(N)nc21 -US05369110,2,CCCNCc1ccc(-c2ccccc2C#N)cc1.COC(=O)C(C)(C)CCC(=O)O>>CCCN(Cc1ccc(-c2ccccc2C#N)cc1)C(=O)CCC(C)(C)C(=O)OC -US07902223B2,7,Cc1cc([N+](=O)[O-])ccc1N1CCCCC1=O>>Cc1cc(N)ccc1N1CCCCC1=O -US07129225B2,1,CCCI.O=Cc1cc([N+](=O)[O-])ccc1O>>CCCOc1ccc([N+](=O)[O-])cc1C=O -US04833146,3,CC(=O)CCCCn1cnc2c1c(=O)n(C)c(=O)n2C.CI>>Cn1c(=O)c2c(ncn2CCCCC(C)(C)O)n(C)c1=O -US07709479B1,7,O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1ccccc1>>Nc1ccc(NC(=O)c2ccccc2)c(Cl)c1 -US20090137557A1,7,Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc2ncccc2c1>>Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc2c(c1)CCCN2 -US20040180934A1,3,CCCC[Sn](CCCC)(CCCC)c1cccn1C.O=C(CC1CCn2c1c(Sc1ccc(Cl)cc1)c1c(Br)cc(F)cc12)N1C(=O)OC[C@@H]1Cc1ccccc1>>Cn1cccc1-c1cc(F)cc2c1c(Sc1ccc(Cl)cc1)c1n2CCC1CC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20120040950A1,10,CCOC(=O)c1c(OC)cc(-c2cnc(OC)c(OC)c2)nc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1c(OC)cc(-c2cnc(OC)c(OC)c2)nc1CBr -US07307094B2,2,CN1C2CCCC1CC(N)C2.COc1cc(Cl)ccc1-c1nc2c(C(=O)O)cccc2o1>>COc1cc(Cl)ccc1-c1nc2c(C(=O)NC3CC4CCCC(C3)N4C)cccc2o1 -US05189043,1,CC(C)N.CCOC(=O)/C=C/CBr>>CCOC(=O)/C=C/CNC(C)C -US20020091270A1,3,Cc1ccc(B(O)O)cc1.O=S(=O)(c1ccc(Br)s1)n1cccc1>>Cc1ccc(-c2ccc(S(=O)(=O)n3cccc3)s2)cc1 -US20070054916A1,7,Cc1c(Cl)cc([N+](=O)[O-])cc1-c1ccc2nc(N)ncc2c1>>Cc1c(Cl)cc(N)cc1-c1ccc2nc(N)ncc2c1 -US05217964,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccccc1>>Cc1ccc(S(=O)(=O)Nc2ccccc2)cc1 -US20130158075A1,6,COC(=O)CCCc1ncc(-c2ccc(NC(=O)c3ccc(C(C)(C)C)cc3)cc2)s1>>CC(C)(C)c1ccc(C(=O)Nc2ccc(-c3cnc(CCCC(=O)O)s3)cc2)cc1 -US07396830B2,2,N=C(c1ccccc1)N1CCNCC1.O=C(Cl)C(=O)c1c[nH]c2cccc(F)c12>>N=C(c1ccccc1)N1CCN(C(=O)C(=O)c2c[nH]c3cccc(F)c23)CC1 -US20120015980A1,6,COC(=O)c1cc(Nc2ccc(C(F)(F)F)cn2)nn1-c1ncccc1Cl>>O=C(O)c1cc(Nc2ccc(C(F)(F)F)cn2)nn1-c1ncccc1Cl -US07354933B2,10,Cc1ccnc(F)c1.O=C1CCC(=O)N1Br>>Fc1cc(CBr)ccn1 -US20080167307A1,1,CCCCBr.OCCCO>>CCCCOCCCO -US20150094296A1,1,CC(C)(CO)n1cc(N)cn1.N#C[C@]1(C2CC2)CCN(c2ccnc(Cl)n2)C1=O>>CC(C)(CO)n1cc(Nc2nccc(N3CC[C@](C#N)(C4CC4)C3=O)n2)cn1 -US08217032B2,1,Oc1ccc2c(C(O)c3ccc(OCCN4CCCCC4)cc3)c(-c3cc(F)cc(F)c3F)ccc2c1>>Oc1ccc2c3c(ccc2c1)-c1cc(F)cc(F)c1OC3c1ccc(OCCN2CCCCC2)cc1 -US05206240,7,CC(=O)N1CCC2(CC1)Cc1ccc([N+](=O)[O-])cc1C2=O>>CC(=O)N1CCC2(CC1)Cc1ccc(N)cc1C2=O -US05719291,2,CCCCCCCCC[C@@H]1OC[C@H](C)C=C1CO.CS(=O)(=O)Cl>>CCCCCCCCC[C@@H]1OC[C@H](C)C=C1COS(C)(=O)=O -US20150182507A1,1,CNCC(=O)OC.ClCc1cn2ccccc2n1>>COC(=O)CN(C)Cc1cn2ccccc2n1 -US20110230462A1,1,Brc1cc(OC2CCCC2)ccn1.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1cc(OC2CCCC2)ccn1 -US20150225452A1,2,C=CC(=O)Cl.N[C@@H]1CCCc2ccccc21>>C=CC(=O)N[C@@H]1CCCc2ccccc21 -US20030078251A1,7,COC(=O)COc1ccc([N+](=O)[O-])c(F)c1>>COC(=O)COc1ccc(N)c(F)c1 -US06235731B1,6,CC(C)(C)OC(=O)N1CCC(CS(=O)(=O)/C=C/C2=Cc3cnc4cccc(n34)S2)CC1>>O=S(=O)(/C=C/C1=Cc2cnc3cccc(n23)S1)CC1CCNCC1 -US05708187,2,CN(C)C1CCc2[nH]c3ccc(N)cc3c2C1.O=C(Cl)c1ccccc1Cl>>CN(C)C1CCc2[nH]c3ccc(NC(=O)c4ccccc4Cl)cc3c2C1 -US06737425B1,1,OCCBr.Oc1cccc(-c2ccccc2)c1>>OCCOc1cccc(-c2ccccc2)c1 -US06586424B2,3,C#CCO.Nc1ccc(Br)cn1>>Nc1ccc(C#CCO)cn1 -US08829026B2,1,CCc1cc(C(=O)OC)ccc1S(=O)(=O)NCc1ccc2c(cnn2C)c1.Fc1ncc(Cl)cc1Cl>>CCc1cc(C(=O)OC)ccc1S(=O)(=O)N(Cc1ccc2c(cnn2C)c1)c1ncc(Cl)cc1Cl -US07381728B2,3,COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(Br)cc1Cl.Cc1ccc(B(O)O)o1>>COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(-c2ccc(C)o2)cc1Cl -US20060025347A1,3,CC(NC(=O)OC(C)(C)C)C(=O)NC(C(=O)N1CCCC1Cc1coc2ccc(OS(=O)(=O)C(F)(F)F)cc12)C(C)C.OB(O)c1cccnc1>>CC(NC(=O)OC(C)(C)C)C(=O)NC(C(=O)N1CCCC1Cc1coc2ccc(-c3cccnc3)cc12)C(C)C -US20090221604A1,9,COc1ccc(N2CCN(c3nc(-c4ccccc4)c(C(N)=O)s3)CC2)cc1>>COc1ccc(N2CCN(c3nc(-c4ccccc4)c(C#N)s3)CC2)cc1 -US20040209865A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.Ic1cnc2c(c1)ncn2CCN1CCCC1>>Clc1ccc(-c2ccc(C#Cc3cnc4c(c3)ncn4CCN3CCCC3)nc2)cc1 -US04134898,2,COC(=O)C1=C(O)c2sccc2S(=O)(=O)N1C.Cc1noc(N)c1C>>Cc1noc(NC(=O)C2=C(O)c3sccc3S(=O)(=O)N2C)c1C -US20130178478A1,1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.NC(=O)c1nnc(Cl)cc1Nc1cccc(C2CCC2)n1>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1cc(Nc2cccc(C3CCC3)n2)c(C(N)=O)nn1 -US20120129811A1,1,CC(C)I.O=[N+]([O-])c1cnccc1O>>CC(C)Oc1ccncc1[N+](=O)[O-] -US20120010189A1,2,CCOC(=O)c1nnc(-c2ccc(OC)cc2)o1.CN(C)Cc1ccc(OC2CNC2)cc1Cl>>COc1ccc(-c2nnc(C(=O)N3CC(Oc4ccc(CN(C)C)c(Cl)c4)C3)o2)cc1 -US20140243290A1,7,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3=CCSCC3)s2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3CCSCC3)s2)c1 -US20090018150A1,1,CC(=O)[O-].COc1ccc(Br)cc1C(=O)CBr>>COc1ccc(Br)cc1C(=O)COC(C)=O -US07842685B2,9,BrC(Br)(Br)Br.OCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1>>Fc1cc(CBr)ccc1-c1nc2ccc(C3(c4ccccc4)CC3)nc2s1 -US09126998B2,6,Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(CNC(=O)OC(C)(C)C)c1ccc(F)c(F)c1>>Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NC(CN)c1ccc(F)c(F)c1 -US20110207702A1,2,O=C=NC1CCCCC1.OB1OCc2ccc(O)cc21>>O=C(NC1CCCCC1)Oc1ccc2c(c1)B(O)OC2 -US07915267B2,6,CCOC(=O)CCCOc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1>>O=C(O)CCCOc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 -US20090105134A1,6,COC(=O)c1cccc(CONC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)NOCc1cccc(C(=O)O)c1 -US20130338134A1,1,COc1cc(OC)c(F)c(N)c1F.C[Si](C)(C)CCOCn1ccc2c(Cl)c(C=O)cnc21>>COc1cc(OC)c(F)c(NCc2cnc3c(ccn3COCC[Si](C)(C)C)c2Cl)c1F -US20130158075A1,6,COC(=O)C(C)(C)CCc1ncc(-c2ccc(NC(=O)N3CCOCC3)cc2)s1>>CC(C)(CCc1ncc(-c2ccc(NC(=O)N3CCOCC3)cc2)s1)C(=O)O -US20090221555A1,1,CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl.Nc1ccc2c(c1)CCN(C(=O)C1COCCO1)CC2>>CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)CCN(C(=O)C2COCCO2)CC3)ncc1Cl -US20080064715A1,8,CC(C)C(O)c1cc2ccncc2[nH]1>>CC(C)C(=O)c1cc2ccncc2[nH]1 -US20120010182A1,1,Cn1nccc1-c1cc(-c2ccccc2)ccc1O.N#Cc1cc(S(=O)(=O)Nc2ncc(F)s2)ccc1F>>Cn1nccc1-c1cc(-c2ccccc2)ccc1Oc1ccc(S(=O)(=O)Nc2ncc(F)s2)cc1C#N -US20130261133A1,3,C#C[C@H](O)CCCCCCCCC.C=C[C@@H](C#CBr)OC(C)=O>>C=C[C@@H](C#CC#C[C@H](O)CCCCCCCCC)OC(C)=O -US05270324,1,CC(C)(O)c1cccc(C(Cl)c2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)c1.CCOC(=O)C(C)CS>>CCOC(=O)C(C)CSC(c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1)c1cccc(C(C)(C)O)c1 -US06413947B1,1,Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CCl)cc2)CCO3)cc1.NC1CCCCC1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CNC4CCCCC4)cc2)CCO3)cc1 -US20150225367A1,7,CC(C)(C)OC(=O)n1cc(-c2cnc(NCC(N)=O)c([N+](=O)[O-])c2)c2ccc(F)cc21>>CC(C)(C)OC(=O)n1cc(-c2cnc(NCC(N)=O)c(N)c2)c2ccc(F)cc21 -US07750012B2,1,FC(F)(F)c1ccc(I)cc1.Oc1ccc(N2CCN(Cc3ccccc3)CC2)cc1>>FC(F)(F)c1ccc(Oc2ccc(N3CCN(Cc4ccccc4)CC3)cc2)cc1 -US20120264735A1,1,Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(O)cn4)c3)n2)cn1.FC(F)(CI)CN1CCOCC1>>Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(OCC(F)(F)CN5CCOCC5)cn4)c3)n2)cn1 -US20150175623A1,4,CCOC(=O)c1cc(CC)sc1N.NC=O>>CCc1cc2c(=O)[nH]cnc2s1 -US08304434B2,2,CC(C)(C1CCNCC1)S(=O)(=O)c1cccc(C(F)(F)F)c1.O=C(O)c1ccc(C(F)(F)F)nc1S(=O)(=O)C1CC1>>CC(C)(C1CCN(C(=O)c2ccc(C(F)(F)F)nc2S(=O)(=O)C2CC2)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1 -US20100152177A1,2,CN1CC=C(c2c[nH]c3ccc(C#N)cc23)CC1.O=S(=O)(Cl)c1ccccc1>>CN1CC=C(c2cn(S(=O)(=O)c3ccccc3)c3ccc(C#N)cc23)CC1 -US08426420B2,6,CCCCOC(=O)NC1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCc2ccccc2)CC1>>CCCCOC(=O)NC1CCN(C(=O)[C@@H](N)CCC(=O)OC(C)(C)C)CC1 -US08124803B2,7,O=C1C2CC3CC1CC(OC(=O)C(F)(F)S(=O)(=O)[O-])(C3)C2>>O=C(OC12CC3CC(C1)C(O)C(C3)C2)C(F)(F)S(=O)(=O)[O-] -US20110136801A1,1,CCOC(=O)COc1cccc(C=O)c1.NCCN1CCCCC1>>CCOC(=O)COc1cccc(CNCCN2CCCCC2)c1 -US20100324041A1,7,O=[N+]([O-])c1c[nH]c2ncc(Br)c(F)c12>>Nc1c[nH]c2ncc(Br)c(F)c12 -US07709505B2,6,COC(=O)c1cc(OC(C)=O)c2cc(C)oc2c1>>COC(=O)c1cc(O)c2cc(C)oc2c1 -US06660742B2,7,CCOC(=O)Cc1c([N+](=O)[O-])cc(OCc2ccccc2)c2ccccc12>>O=[N+]([O-])c1cc(OCc2ccccc2)c2ccccc2c1CCO -US06331538B1,1,CC(C)(C)OC(=O)NC1CCNC1.COc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(F)cc32)cc1>>COc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(N4CCC(NC(=O)OC(C)(C)C)C4)cc32)cc1 -US20100075961A1,9,CCC(C(=O)O)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1.N>>CCC(C(N)=O)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 -US20070037807A1,2,C1CCC(NC2CCCCC2)CC1.Cc1ccc(-c2c(C#N)c(CC(C)C)nc(C)c2C(=O)O)cc1>>Cc1ccc(-c2c(C#N)c(CC(C)C)nc(C)c2C(=O)N(C2CCCCC2)C2CCCCC2)cc1 -US06174898B1,7,Cc1ccccc1C(=CCOCCN1CCC[C@@H](C(=O)O)C1)c1ccccc1C>>Cc1ccccc1C(CCOCCN1CCC[C@@H](C(=O)O)C1)c1ccccc1C -US20140275016A1,7,O=C(Nc1cc(Oc2ccc([N+](=O)[O-])nc2)ccn1)C1CC1>>Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)cn1 -US05795894,3,Clc1cnccn1.[Mg+]c1ccccc1>>c1ccc(-c2cnccn2)cc1 -US09120749B2,1,CC(C)(C)OC(=O)N1CCN(c2ncc(N)cn2)CC1.O=C(c1cnc2ccc(Br)cc2c1Cl)C1CC1>>CC(C)(C)OC(=O)N1CCN(c2ncc(Nc3c(C(=O)C4CC4)cnc4ccc(Br)cc34)cn2)CC1 -US07199120B2,1,Clc1cccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccco3)nn12.NC1CC1>>c1coc(-c2nn3c(NC4CC4)cccc3c2-c2ccnc(NC3CCCC3)n2)c1 -US07495007B2,1,FC(F)(F)CI.O=Cc1cc(Cl)ccc1O>>O=Cc1cc(Cl)ccc1OCC(F)(F)F -US20110306769A1,9,N#Cc1cc(-c2ccccc2F)[nH]c1Cl>>N#Cc1c[nH]c(-c2ccccc2F)c1 -US20110009381A1,3,COC(=O)c1cc(N2CCOCC2)nc(Cl)n1.OB(O)c1ccccc1>>COC(=O)c1cc(N2CCOCC2)nc(-c2ccccc2)n1 -US07279470B2,2,C1CCC(CN2CCNCC2)CC1.O=C(Cl)Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1>>O=C(Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1)N1CCN(CC2CCCCC2)CC1 -US07176224B2,1,CCOC(=O)C(C)Br.Cc1ccc(O)cc1>>CCOC(=O)C(C)Oc1ccc(C)cc1 -US20030109752A1,1,CCOc1ccccc1OCCBr.COc1ccc(CC(C)N)cc1S(N)(=O)=O>>CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(S(N)(=O)=O)c1 -US20150166480A1,3,CC(C)(CN1CCC(COc2ccc(Br)cn2)CC1)C(F)(F)F.COC(=O)c1ccc(B(O)O)cc1>>COC(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)C(F)(F)F)CC3)nc2)cc1 -US20100048636A1,7,Cc1cc(F)cc(C(=O)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1>>Cc1cc(F)cc([C@H](O)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1 -US07897762B2,2,CC(=O)Cl.CCOC(=O)C(=O)c1cc(N)c(F)cc1C>>CCOC(=O)C(=O)c1cc(NC(C)=O)c(F)cc1C -US20130035310A1,2,O=C(O)CCn1ccc2cc(Cl)ccc21.O=S(=O)(Nc1ccncn1)c1ccc(N2CCNCC2)cc1>>O=C(CCn1ccc2cc(Cl)ccc21)N1CCN(c2ccc(S(=O)(=O)Nc3ccncn3)cc2)CC1 -US06265398B1,1,COc1ccc2c(c1)CCC(OS(C)(=O)=O)C2.[N-]=[N+]=[N-]>>COc1ccc2c(c1)CCC(N=[N+]=[N-])C2 -US06284755B1,1,CCC1(c2cccc(O)c2)CCCCN(C)C1=O.N#Cc1ccc(C(O)c2cccnc2)cc1F>>CCC1(c2cccc(Oc3cc(C(O)c4cccnc4)ccc3C#N)c2)CCCCN(C)C1=O -US20120004201A1,2,CCn1ncc2c(NC3CCCCC3)c(C(=O)O)c(C)nc21.CNOC>>CCn1ncc2c(NC3CCCCC3)c(C(=O)N(C)OC)c(C)nc21 -US20140213586A1,3,CN(C)C=O.Fc1cccc2[nH]ccc12>>O=Cc1c[nH]c2cccc(F)c12 -US20150126550A1,3,CC(C)(C)OC(=O)N1CCC[C@H]1C=O.CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)CP(=O)(OCC)OCC>>CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)/C=C/[C@@H]1CCCN1C(=O)OC(C)(C)C -US20140275080A1,1,Brc1cnc(Br)cn1.Oc1ccnc(Cl)c1>>Clc1cc(Oc2cnc(Br)cn2)ccn1 -US03954813,6,CCCCCC(O)CCc1ccc(CCCCCCCC(=O)OCC)o1>>CCCCCC(O)CCc1ccc(CCCCCCCC(=O)O)o1 -US20090264650A1,1,O=C1C(Cc2c(Cl)cccc2Cl)C(CO)CN1C1CCCCC1.Oc1ccccc1>>O=C1C(Cc2c(Cl)cccc2Cl)C(COc2ccccc2)CN1C1CCCCC1 -US20150182513A1,6,C[C@@](CCn1ccc(-c2ccccc2)cc1=O)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>C[C@@](CCn1ccc(-c2ccccc2)cc1=O)(C(=O)NO)S(C)(=O)=O -US20150191472A1,9,CC(C)(C)OC(=O)N1[C@H](CO)[C@H]2OC(C)(C)O[C@H]2[C@@H]1c1c[nH]c2c(Cl)ncnc12.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1[C@@H](c2c[nH]c3c(N=[N+]=[N-])ncnc23)[C@@H]2OC(C)(C)O[C@@H]2[C@@H]1CO -US20150080549A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.[N-]=[N+]=Nc1ccc(COC(=O)NCCCCC(N)C(=O)O)cc1>>CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccc(N=[N+]=[N-])cc1)C(=O)O -US07528262B2,1,CI.OCCc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1>>COCCc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1 -US20080076758A1,6,CN(CC1CCCN1C(=O)OC(C)(C)C)S(C)(=O)=O>>CN(CC1CCCN1)S(C)(=O)=O -US08269043B2,1,CC(C)(C)OC(=O)NC1(c2ccc3cc(O)ccc3c2)COC(C)(C)OC1.CCCC[C@@H]1CC[C@@H](O)CC1>>CCCC[C@@H]1CC[C@H](Oc2ccc3cc(C4(NC(=O)OC(C)(C)C)COC(C)(C)OC4)ccc3c2)CC1 -US20140235621A1,2,CC(C)(C)OC(=O)N(CCO)Cc1cc(F)cc2cc[nH]c12.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N(CCOS(C)(=O)=O)Cc1cc(F)cc2cc[nH]c12 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@@H](O)c3ccccc3)CC2)c1.Oc1ccc(F)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](Oc3ccc(F)cc3)c3ccccc3)CC2)c1 -US20100094021A1,1,CNCC1CCN(Cc2ccc3c(c2)OCO3)C1.Clc1nc(-n2ccnc2)ns1>>CN(CC1CCN(Cc2ccc3c(c2)OCO3)C1)c1nc(-n2ccnc2)ns1 -US20070249670A1,6,CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)OCc1ccccc1>>CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)O -US06787536B2,2,Brc1ccc(N2CCNCC2)cc1.CC(C)C(CS(=O)(=O)Cl)C(=O)OC(C)(C)C>>CC(C)C(CS(=O)(=O)N1CCN(c2ccc(Br)cc2)CC1)C(=O)OC(C)(C)C -US20110190263A1,2,CC1(O)CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC1(OC(=O)Oc2ccc([N+](=O)[O-])cc2)CC1 -US05183492,7,CCOC(=O)C(C)(C)OC(=O)c1cc([N+](=O)[O-])c(F)cc1Cl>>CCOC(=O)C(C)(C)OC(=O)c1cc(N)c(F)cc1Cl -US20060035933A1,5,COc1cc([N+](=O)[O-])ccc1C=O.OCCO>>COc1cc([N+](=O)[O-])ccc1C1OCCO1 -US20060142337A1,2,CN.C[C@@H](O[C@H]1CCN(C(=O)CCC(=O)O)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CNC(=O)CCC(=O)N1CC[C@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](c2ccccc2)C1 -US08486962B2,7,CCCN(CCC)c1ccc([N+](=O)[O-])cn1>>CCCN(CCC)c1ccc(N)cn1 -US06136837,7,Cc1cc(Cl)ccc1OCc1ccccc1C(=O)c1nccn1C>>Cc1cc(Cl)ccc1OCc1ccccc1C(O)c1nccn1C -US20040068016A1,1,C[S-].O=C1c2ccc(Cl)cc2CC1Br>>CSC1Cc2cc(Cl)ccc2C1=O -US20040132727A1,2,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.Cc1ccc(C(=O)N=C=S)cc1>>COc1cc2ncnc(Oc3ccc(NC(=S)NC(=O)c4ccc(C)cc4)cc3)c2cc1OC -US04225609,6,CCOC(=O)c1ccc(CCCC2SCC(=O)N2CCC2=CCCCC2)cc1>>O=C(O)c1ccc(CCCC2SCC(=O)N2CCC2=CCCCC2)cc1 -US06211234B1,1,COC(=O)c1ccc(OCc2ccccc2)cc1O.Cc1ccccc1C(C)O>>COC(=O)c1ccc(OCc2ccccc2)cc1OC(C)c1ccccc1C -US08946260B2,1,Ic1cnccc1C1CC1.O=C1NCCc2ccc(Cl)cc21>>O=C1c2cc(Cl)ccc2CCN1c1cnccc1C1CC1 -US07202363B2,3,CC1(C)OB(c2ccsc2C=O)OC1(C)C.COc1cc(-c2csc3c(I)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C>>COc1cc(-c2csc3c(-c4ccsc4C=O)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C -US20150225422A1,1,CC1CCCCN1.N#Cc1ncc(Br)cc1F>>CC1CCCCN1c1cc(Br)cnc1C#N -US20040106645A1,1,O=C(CCCCCl)c1ccc(F)cc1.O=c1cc(NC2CCNCC2)c2cc(Cl)ccc2o1>>O=C(CCCCN1CCC(Nc2cc(=O)oc3ccc(Cl)cc23)CC1)c1ccc(F)cc1 -US07582773B2,4,Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cc(-c3ccc(OCC#N)cc3)ccc12.[N-]=[N+]=[N-]>>Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cc(-c3ccc(OCc4nnn[nH]4)cc3)ccc12 -US08673942B2,1,COC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cn3)cc(O)c2[nH]1.COCC(O)COC>>COCC(COC)Oc1cc(Oc2ccc(S(C)(=O)=O)cn2)cc2cc(C(=O)OC)[nH]c12 -US08846972B2,6,CC(NC(=O)OCc1ccccc1)C(C)NC(=O)c1ccccc1O>>CC(N)C(C)NC(=O)c1ccccc1O -US04683228,1,CCOC(=O)CCBr.O=[N+]([O-])c1cc[nH]n1>>CCOC(=O)CCn1ccc([N+](=O)[O-])n1 -US20070123532A1,6,COc1ccc(C[C@@H]2CN(Cc3ccccc3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1>>COc1ccc(C[C@@H]2CNCCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1 -US20150239884A1,1,COCCBr.Clc1cc2c(-c3cn[nH]c3)cccc2cn1>>COCCn1cc(-c2cccc3cnc(Cl)cc23)cn1 -US07365061B2,8,O=C(N[C@@H]1Cc2ccccc2C[C@H]1O)OCc1ccccc1>>O=C(NC1Cc2ccccc2CC1=O)OCc1ccccc1 -US20040209886A1,1,COC(=O)c1cn2ncc(C#N)c(Cl)c2c1C.COc1ccccc1Oc1ccc(N)cc1>>COC(=O)c1cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4OC)cc3)c2c1C -US06300352B1,1,CCOC(=O)[C@@H](C)O.Oc1ccc(Br)cc1>>CCOC(=O)[C@H](C)Oc1ccc(Br)cc1 -US05296499,1,CCI.COc1ccc(-c2c(C(=O)O)[nH]c3cc(OC)c(OC)cc23)cc1OC>>CCOC(=O)c1[nH]c2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1 -US04386035,7,O=C(O)c1ccc(F)c(Br)c1>>OCc1ccc(F)c(Br)c1 -US20080090854A1,6,CC(C)(C)OC(=O)C(C)(C)NC(=O)c1cc(Cl)c2ccccc2c1OCc1cnc(C(F)(F)F)nc1>>CC(C)(NC(=O)c1cc(Cl)c2ccccc2c1OCc1cnc(C(F)(F)F)nc1)C(=O)O -US20120022082A1,2,CS(=O)(=O)Cl.Nc1ncc(-c2ccc(CCCO)cc2)nc1C(=O)Nc1cccnc1>>CS(=O)(=O)OCCCc1ccc(-c2cnc(N)c(C(=O)Nc3cccnc3)n2)cc1 -US20080280875A1,1,C=C(C)CBr.COC(=O)c1cc(O)cc(O)c1>>C=C(C)COc1cc(O)cc(C(=O)OC)c1 -US08598154B2,1,BrCC1CC1.O=S(=O)(c1ccc(N2CCOCC2)nc1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(CO)C1>>O=S(=O)(c1ccc(N2CCOCC2)nc1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(COCC2CC2)C1 -US20080261946A1,1,CCOC(=O)CBr.Cc1ccc(O)c(C#N)c1>>CCOC(=O)COc1ccc(C)cc1C#N -US04977155,6,CCOC(=O)c1cc2c(ccc3nc(O)c(O)nc32)s1>>O=C(O)c1cc2c(ccc3nc(O)c(O)nc32)s1 -US06207686B1,1,BrCc1ccccc1.CC(C)(C)OC(=O)C(Cc1ccccc1C(=O)O)C(O)C1CCCCC1>>CC(C)(C)OC(=O)C(Cc1ccccc1C(=O)OCc1ccccc1)C(O)C1CCCCC1 -US06277861B1,7,CC1c2cccc(N)c2C=CN1C>>CC1c2cccc(N)c2CCN1C -US09050345B2,2,COC(=O)c1c(-c2ccccc2)ccn1N.NS(=O)(=O)c1cncc(C(=O)O)c1>>COC(=O)c1c(-c2ccccc2)ccn1NC(=O)c1cncc(S(N)(=O)=O)c1 -US08394799B2,2,COC(=O)c1ccnc(N)c1.O=C(O)COc1ccc(Cl)cc1Cl>>COC(=O)c1ccnc(NC(=O)COc2ccc(Cl)cc2Cl)c1 -US20100016401A1,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CN)c1.Cc1nc(Br)sc1C(=O)O>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)c2sc(Br)nc2C)c1 -US20100204207A1,7,Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)C)CCCC2N(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccnc1>>Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)C)CCCC2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccnc1 -US04336255,1,N=C(N)N.O=[N+]([O-])c1c(Cl)ncnc1Cl>>N=C(N)Nc1ncnc(Cl)c1[N+](=O)[O-] -US07022699B2,3,CCCC[Sn](CCCC)(CCCC)c1ccc(C(=O)OCC)cc1.O=S(=O)(OC1=CCCc2ccccc21)C(F)(F)F>>CCOC(=O)c1ccc(C2=CCCc3ccccc32)cc1 -US07268128B2,6,COC(=O)/C=C/c1ccc(-c2nc3c(C)nn(C4CCCCC4)c3c(=O)[nH]2)c(OC)c1>>COc1cc(/C=C/C(=O)O)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1 -US05614541,3,CN1C(=O)CSC1=S.O=Cc1cc(O)c(O)c([N+](=O)[O-])c1>>CN1C(=O)C(=Cc2cc(O)c(O)c([N+](=O)[O-])c2)SC1=S -US05968944,4,CCC(=O)C(C(=O)CC)C(=O)OC.NNc1c(Cl)cc(C(F)(F)F)cc1Cl>>CCc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(CC)c1C(=O)OC -US20120058984A1,1,CSc1nc(N)cc(Cc2ccccc2)n1.Clc1nc2ccccc2s1>>CSc1nc(Cc2ccccc2)cc(Nc2nc3ccccc3s2)n1 -US20050004207A1,1,N#CCBr.OCc1cccc(O)c1>>N#CCOc1cccc(CO)c1 -US20050245504A1,6,COC(=O)c1ccc2c(C)noc2c1>>Cc1noc2cc(C(=O)O)ccc12 -US20130331372A1,3,COc1cc(F)c(C(C)C)cc1B(O)O.C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1nc(Cl)ccc1Br>>COc1cc(F)c(C(C)C)cc1-c1ccc(Cl)nc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C -US20060063784A1,3,CC(C)CC(=O)Nc1cccc(-c2ccnc3c(Br)cnn23)c1.COc1ccc(B(O)O)cc1C=O>>COc1ccc(-c2cnn3c(-c4cccc(NC(=O)CC(C)C)c4)ccnc23)cc1C=O -US08394570B2,2,O=C(Cl)C12CC3CC(CC(C3)C1)C2.O=S(=O)([O-])CCCO>>O=C(OCCCS(=O)(=O)[O-])C12CC3CC(CC(C3)C1)C2 -US08501732B2,2,Cn1cc(C(=O)O)cn1.NCc1c(-c2ncco2)n(-c2ccccc2)c2ncccc2c1=O>>Cn1cc(C(=O)NCc2c(-c3ncco3)n(-c3ccccc3)c3ncccc3c2=O)cn1 -US20080275021A1,2,CC(=O)N1C[C@H](O)C[C@H]1C(=O)O.CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1CNC[C@H]1c1ccccc1>>CC(=O)N1C[C@H](O)C[C@H]1C(=O)N1C[C@@H](c2ccccc2)[C@H](N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1 -US07674803B2,1,CCBr.COC(=O)C(C)NS(=O)(=O)c1ccccc1[N+](=O)[O-]>>CCN(C(C)C(=O)OC)S(=O)(=O)c1ccccc1[N+](=O)[O-] -USRE030634,9,CCC(=O)c1ccc(Cl)cc1.NO>>CCC(=NO)c1ccc(Cl)cc1 -US06780992B2,1,CCCc1nc(C)cc(=O)[nH]1.O=Cc1ccc(OCCBr)cc1>>CCCc1nc(C)cc(=O)n1CCOc1ccc(C=O)cc1 -US20100331378A1,1,CC1(c2ccc(CCl)o2)OCCO1.O=[N+]([O-])c1cn[nH]n1>>CC1(c2ccc(Cn3ncc([N+](=O)[O-])n3)o2)OCCO1 -US06812226B2,1,O=C(O)c1cnc(Cl)c(Cl)c1.O=C1OCc2ccccc2N1C1CCNCC1>>O=C(O)c1cnc(N2CCC(N3C(=O)OCc4ccccc43)CC2)c(Cl)c1 -US20080312234A1,2,CS(=O)(=O)Nc1c(F)cc(CN)cc1C(F)(F)F.O=C(O)C=Cc1ccc(C(F)(F)F)nc1N1CCOCC1>>CS(=O)(=O)Nc1c(F)cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2N2CCOCC2)cc1C(F)(F)F -US20040110789A1,1,Nc1ccccc1.O=C1CN2CCC1CC2>>c1ccc(NC2CN3CCC2CC3)cc1 -US20110312945A1,9,Cc1[nH]c2c(c1C(O)c1ccc(S(=O)(=O)N3CCOCC3)cc1)C(=O)CC(C)(C)C2>>Cc1[nH]c2c(c1Cc1ccc(S(=O)(=O)N3CCOCC3)cc1)C(=O)CC(C)(C)C2 -US04696990,1,C=C(C)C(=O)[O-].OCCCCCCCl>>C=C(C)C(=O)OCCCCCCO -US20090069328A1,3,C#C[Si](C)(C)C.COC(=O)c1cc(Br)ccc1OC(F)(F)F>>COC(=O)c1cc(C#C[Si](C)(C)C)ccc1OC(F)(F)F -US20010016576A1,2,CC(=O)C(=O)Cl.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1>>CC(=O)C(=O)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O -US20120088746A1,2,Cc1cc([C@@H](C)N)c(F)cc1NS(C)(=O)=O.O=C(O)c1ccc2nc(C(F)(F)F)cc(N3CC[C@H](O)C3)c2c1>>Cc1cc([C@@H](C)NC(=O)c2ccc3nc(C(F)(F)F)cc(N4CC[C@H](O)C4)c3c2)c(F)cc1NS(C)(=O)=O -US05348965,1,CCOC(=O)[C@@H]1CCCNC1.OCCCOCC=C1c2ccccc2CCc2ccccc21>>CCOC(=O)[C@@H]1CCCN(CCCOCC=C2c3ccccc3CCc3ccccc32)C1 -US20140005168A1,6,CC(C)(C)OC(=O)N1CCCN(c2cccc(-n3ncc4cnc(-c5cnn(CC6CC6)c5)cc43)n2)CC1>>c1cc(N2CCCNCC2)nc(-n2ncc3cnc(-c4cnn(CC5CC5)c4)cc32)c1 -US20110275797A1,6,O=C(O)c1cc(-c2cccnc2)ccc1OCc1ccccc1>>O=C(O)c1cc(-c2cccnc2)ccc1O -US07605158B2,6,COC(=O)CCCCC(=O)Nc1c(C(=O)Nc2ccc(Cl)cn2)oc2ccccc12>>O=C(O)CCCCC(=O)Nc1c(C(=O)Nc2ccc(Cl)cn2)oc2ccccc12 -US07629363B2,3,C#Cc1ccc(F)cc1.Cc1cc(OS(=O)(=O)C(F)(F)F)c(Br)c(=O)n1Cc1cccnc1>>Cc1cc(C#Cc2ccc(F)cc2)c(Br)c(=O)n1Cc1cccnc1 -US06048884,4,COC(=O)CC(=O)CCl.NC(=S)NCc1ccccc1>>COC(=O)Cc1csc(NCc2ccccc2)n1 -US20070249670A1,2,CCCCOC[C@H](N)C(=O)OC.Nc1cc2ccccc2cc1C(=O)O>>CCCCOC[C@H](NC(=O)c1cc2ccccc2cc1N)C(=O)OC -US04181631,8,CCC(C)(CC)C1CCC(O)CC1>>CCC(C)(CC)C1CCC(=O)CC1 -US04052507,2,Cn1cc(C(=O)NCCC2CCN(S(N)(=O)=O)CC2)c(=O)n(C)c1=O.O=C=NC12CC3CC(CC(C3)C1)C2>>Cn1cc(C(=O)NCCC2CCN(S(=O)(=O)NC(=O)NC34CC5CC(CC(C5)C3)C4)CC2)c(=O)n(C)c1=O -US20070213338A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H](NCCc1ccccc1)c1cccc(C(C)(C)O[SiH2]C(C)(C)C)n1>>C[C@@H](c1cccc(C(C)(C)O[SiH2]C(C)(C)C)n1)N(CCc1ccccc1)C(=O)OC(C)(C)C -US20030186970A1,1,CC=O.CCC1COc2cc([N+](=O)[O-])ccc2N1>>CCC1COc2cc([N+](=O)[O-])ccc2N1CC -US20120184561A1,2,CCN(CC)Cc1ccc(N)cc1C(F)(F)F.Cc1cc(-n2cnc3cccnc32)ccc1CC(=O)O>>CCN(CC)Cc1ccc(NC(=O)Cc2ccc(-n3cnc4cccnc43)cc2C)cc1C(F)(F)F -US20140364605A1,1,Brc1ccc2c3ccccc3n(-c3ccccn3)c2c1.c1ccc2c(c1)[nH]c1cc(-n3cccn3)ccc12>>c1ccc(-n2c3ccccc3c3ccc(-n4c5ccccc5c5ccc(-n6cccn6)cc54)cc32)nc1 -US20050054629A1,1,O=c1cc(COC2CCCCO2)occ1OCCCCBr.c1ccc2[nH]ccc2c1>>O=c1cc(COC2CCCCO2)occ1OCCCCn1ccc2ccccc21 -US08557830B2,8,Cc1ccc2cnccc2c1[N+](=O)[O-].O=C(OO)c1cccc(Cl)c1>>Cc1ccc2c[n+]([O-])ccc2c1[N+](=O)[O-] -US20040167126A1,2,CC(C)(C)OC(=O)N[C@H](CC1CCCCC1)C(O)C(=O)O.NNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@H](CC1CCCCC1)C(O)C(=O)NNC(=O)OCc1ccccc1 -US20060105997A1,2,N[C@H](C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1)C1CC1.O=S(=O)(Cl)CCCl>>O=C([C@@H](NS(=O)(=O)CCCl)C1CC1)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1 -US04401597,6,COC(=O)c1nc(C)n2c1CN=C(c1ccccc1)c1cc(Cl)ccc1-2>>Cc1nc(C(=O)O)c2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2 -US20120184587A1,6,COc1c(Cl)cc(C(=O)N2CS(=O)(=O)c3ccccc32)cc1C#N>>N#Cc1cc(C(=O)N2CS(=O)(=O)c3ccccc32)cc(Cl)c1O -US20110212945A1,3,O=[N+]([O-])c1cnc(Cl)c(I)c1.OB(O)c1ccccc1>>O=[N+]([O-])c1cnc(Cl)c(-c2ccccc2)c1 -US20150218150A1,3,CC(C)(C)OC(=O)Nc1cncc(B2OC(C)(C)C(C)(C)O2)c1.O=C1NCc2cc(-c3ccc(I)s3)ccc21>>CC(C)(C)OC(=O)Nc1cncc(-c2ccc(-c3ccc4c(c3)CNC4=O)s2)c1 -US08084479B2,2,CC(=O)OC(C)=O.N[C@H](CNc1ncc(-c2ccc3c(c2)CC(=O)N3)s1)Cc1ccc(C(F)(F)F)cc1>>CC(=O)N[C@H](CNc1ncc(-c2ccc3c(c2)CC(=O)N3)s1)Cc1ccc(C(F)(F)F)cc1 -US20090124619A1,6,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)NCC1CN(S(=O)(=O)c2ccc(Cl)cc2Cl)CCO1>>CC(C)C[C@H](N)C(=O)NCC1CN(S(=O)(=O)c2ccc(Cl)cc2Cl)CCO1 -US06110962,1,COC(=O)[C@@H](O)Cc1ccccc1.COc1c2ccccc2c(-c2cc(Br)c(O)c(Br)c2)c2c1sc1ccccc12>>COC(=O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(OC)c3sc4ccccc4c23)cc1Br -US07741341B2,1,COC(=O)c1cccc2[nH]c(C(=O)Nc3ccc(C(=O)N4CCCC4)cc3F)nc12.O=C(CBr)Nc1ccc(Cl)cn1>>COC(=O)c1cccc2c1nc(C(=O)Nc1ccc(C(=O)N3CCCC3)cc1F)n2CC(=O)Nc1ccc(Cl)cn1 -US06054457,6,COc1cc(C(=O)N(C)c2ccc(O)cc2)ccc1NC(=O)c1ccccc1OCCCNC(=O)OC(C)(C)C>>COc1cc(C(=O)N(C)c2ccc(O)cc2)ccc1NC(=O)c1ccccc1OCCCN -US20150065482A1,1,Fc1cncc(Br)c1.O=C(O)c1n[nH]c2ncccc12>>O=C(O)c1nn(-c2cncc(Br)c2)c2ncccc12 -US20060089394A1,3,CCOC(=O)CP(=O)(OCC)OCC.Cc1cc(OCc2ccccc2)ccc1C=O>>CCOC(=O)/C=C/c1ccc(OCc2ccccc2)cc1C -US20100098634A1,7,COc1ccc([N+](=O)[O-])c(O)c1>>COc1ccc(N)c(O)c1 -US04528114,9,BrC(Br)(Br)Br.N#C[C@@H]1CC[C@@H](C=O)CC1>>N#C[C@@H]1CC[C@@H](C=C(Br)Br)CC1 -US20110065702A1,3,C[Si](C)(C)CCOCn1nc(CCc2ccncc2)c2ccc(C=O)cc21.O=C1Cc2ccccc2N1>>C[Si](C)(C)CCOCn1nc(CCc2ccncc2)c2ccc(C=C3C(=O)Nc4ccccc43)cc21 -US09085578B2,3,CC1(C)OB(c2csc(CC#N)c2)OC1(C)C.Nc1n[nH]c2c(Br)cn(-c3ccccc3Cl)c(=O)c12>>N#CCc1cc(-c2cn(-c3ccccc3Cl)c(=O)c3c(N)n[nH]c23)cs1 -US20050038043A1,1,CC(=O)OCCc1c(Cl)ncnc1CBr.Fc1cccnc1-c1ncc[nH]1>>CC(=O)OCCc1c(Cl)ncnc1Cn1ccnc1-c1ncccc1F -US04418071,6,CCOC(=O)c1c(CBr)n(C(C)=O)c(=O)n1C(C)=O>>CCOC(=O)c1c(CBr)[nH]c(=O)n1C(C)=O -US06670379B2,9,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N[C@@H](CO)Cc1cccnc1>>CC(C)(C)OC(=O)N[C@@H](CBr)Cc1cccnc1 -US20150031684A1,2,NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCC[NH2+]3)c21.O=C(O)c1ccnnc1>>NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCCN3C(=O)c3ccnnc3)c21 -US07998959B2,1,CC(C)C=O.O=C(NC1CCCCC1)C1CC2(CC2)CN1>>CC(C)CN1CC2(CC2)CC1C(=O)NC1CCCCC1 -US20150018547A1,1,COC(=O)CC(=O)CCl.COc1cc(Cl)cc(S)c1F>>COC(=O)CC(=O)CSc1cc(Cl)cc(OC)c1F -US04248876,2,CC(=O)Cl.CN1C[C@@H](O)C[C@@H](c2ccccc2)C1>>CC(=O)O[C@H]1C[C@@H](c2ccccc2)CN(C)C1 -US20120059014A1,6,COc1cnc(Cl)nc1C>>Cc1nc(Cl)ncc1O -US20100105655A1,6,COc1cc(N2CC[C@@H](NC(C)=O)C2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1>>COc1cc(N2CC[C@@H](N)C2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 -US20070287725A1,1,NCc1cc(-c2cccnc2)on1.O=[N+]([O-])c1cnc2ccccc2c1Cl>>O=[N+]([O-])c1cnc2ccccc2c1NCc1cc(-c2cccnc2)on1 -US20140107340A1,2,NCC1(c2ccc(F)nc2)CCC(F)(F)CC1.O=C(O)c1cccc(Cl)c1F>>O=C(NCC1(c2ccc(F)nc2)CCC(F)(F)CC1)c1cccc(Cl)c1F -US20130237540A1,2,Cn1ncc(Br)c1-c1cc(N)ccc1OCCN1CCCC1.O=C=Nc1ccc(F)cc1F>>Cn1ncc(Br)c1-c1cc(NC(=O)Nc2ccc(F)cc2F)ccc1OCCN1CCCC1 -US20100113502A1,1,CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CN(C(=O)OC(C)(C)C)CC4)CC1.CN(C)C(=O)CCl>>CC1CCN(C(=O)c2ccc3c(c2)c2c(n3CC(=O)N(C)C)CCN(C(=O)OC(C)(C)C)C2)CC1 -US20140088053A1,9,BrC(Br)(Br)Br.C[C@]12CC[C@@H]3c4ccc(CO)cc4CC[C@H]3[C@@H]1C[C@H](Cc1cccc(C(N)=O)c1)[C@@H]2O>>C[C@]12CC[C@@H]3c4ccc(CBr)cc4CC[C@H]3[C@@H]1C[C@H](Cc1cccc(C(N)=O)c1)[C@@H]2O -US20110178064A1,3,C[C@H]1CN(c2ncc(Br)cc2C=O)C[C@@H](C)O1.OB(O)c1cc2ccccc2o1>>C[C@H]1CN(c2ncc(-c3cc4ccccc4o3)cc2C=O)C[C@@H](C)O1 -US20130267681A1,7,COc1ccc(C2=N[C@@H](Cc3ccccc3)C(=O)SC2)c(OC)c1>>COc1ccc([C@@H]2CSC(=O)[C@H](Cc3ccccc3)N2)c(OC)c1 -US20090221645A1,3,CN(C)C=O.Clc1ccc2cccc(C3=C(Br)SC4=NCCN43)c2c1>>O=CC1=C(c2cccc3ccc(Cl)cc23)N2CCN=C2S1 -US20110288084A1,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=C1COc2ccc(CN[C@@H]3CC[C@@H](C(O)CNS(=O)(=O)c4ccccc4[N+](=O)[O-])CC3)nc2N1>>O=C1COc2ccc(CN(C(=O)C(F)(F)F)[C@@H]3CC[C@@H](C(O)CNS(=O)(=O)c4ccccc4[N+](=O)[O-])CC3)nc2N1 -US20090215743A1,2,C1COCCN1.COc1cccc(C2OC(CC(=O)O)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC>>COc1cccc(C2OC(CC(=O)N3CCOCC3)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC -US20080132477A1,3,N#Cc1cccc(I)c1.OB(O)C1CC1>>N#Cc1cccc(C2CC2)c1 -US20110224193A1,2,O=C(Cl)OC1CCCC1.O=C(Nc1ccc(N2CCNCC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F>>O=C(Nc1ccc(N2CCN(C(=O)OC3CCCC3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US20120134934A1,1,CC(C)(C)OC(=O)NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1.O=C(CCl)c1ccccc1>>CC(C)(C)OC(=O)NC(C(=O)O[C@H]1C[N+]2(CC(=O)c3ccccc3)CCC1CC2)c1ccccc1 -US08309734B2,2,NCC(=O)O.O=C(O)CCc1cc(Cl)c(Oc2ncccc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl>>O=C(O)CNC(=O)CCc1cc(Cl)c(Oc2ncccc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl -US04564612,1,CC(C)(C)OC(=O)CCl.O=C1Nc2ccccc2SC[C@@H]1N1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)CN1C(=O)[C@@H](N2C(=O)c3ccccc3C2=O)CSc2ccccc21 -US05196454,1,CCCN(CCC)C1CCc2c(cccc2NC(C)=O)C1.ClCc1ccccc1>>CCCN(CCC)C1CCc2c(cccc2N(Cc2ccccc2)C(C)=O)C1 -US08372874B2,2,CC(C)(SCC[C@H]1CCOC1)C(=O)O.C[C@H](OC1CCCCO1)C(C)(C)c1cc(N)on1>>C[C@H](OC1CCCCO1)C(C)(C)c1cc(NC(=O)C(C)(C)SCC[C@H]2CCOC2)on1 -US20130165485A1,6,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2=NO)ccc1C(=O)OC(C)(C)C>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2=NO)ccc1C(=O)O -US20040242499A1,6,CCCCCCCCCCCCCCCCCC(=O)NC(CS[C@@H]1O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O)C(=O)OC>>CCCCCCCCCCCCCCCCCC(=O)NC(CS[C@@H]1O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O)C(=O)O -US20050209324A1,2,CCO.COc1c(F)cccc1C1(CC(=O)C(=O)O)CC1>>CCOC(=O)C(=O)CC1(c2cccc(F)c2OC)CC1 -US20110319378A1,2,CO.O=C(O)CCC(c1cccc(Cl)c1)C1(Br)C(=O)Nc2cc(Cl)ccc21>>COC(=O)CCC(c1cccc(Cl)c1)C1(Br)C(=O)Nc2cc(Cl)ccc21 -US20150175584A1,1,COc1ccc2c(Cl)ncnc2c1OC.NC1CCOC1>>COc1ccc2c(NC3CCOC3)ncnc2c1OC -US06313310B1,3,C#CC(O)c1cccc(OC)c1OC.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CC(O)c3cccc(OC)c3OC)c21 -US04410537,6,COC(=O)c1cccc(COc2cccc(OC)c2C=O)c1>>COC(=O)c1cccc(COc2cccc(O)c2C=O)c1 -US20150087644A1,10,Cc1cncc(Br)n1.O=C1CCC(=O)N1Br>>BrCc1cncc(Br)n1 -US20060252777A1,4,C=C(CC(=O)O)C(=O)O.COc1ccc(N)cc1F>>COc1ccc(N2CC(C(=O)O)CC2=O)cc1F -US04629795,1,C=C(c1ccccc1O)n1ccnc1.ClCc1ccc(Cl)cc1Cl>>C=C(c1ccccc1OCc1ccc(Cl)cc1Cl)n1ccnc1 -US20110152095A1,6,COC(=O)COC(C)(C)C#Cc1cc(-c2ccc(Cl)cc2)ccc1C>>Cc1ccc(-c2ccc(Cl)cc2)cc1C#CC(C)(C)OCC(=O)O -US20100137305A1,3,C[Mg+].O=C1CCN(Cc2ccccc2)C1>>CC1(O)CCN(Cc2ccccc2)C1 -US07462617B2,2,CC(=O)c1ccc(N2CCNCC2)c(F)c1.COC(=O)c1ccc([N+](=O)[O-])cc1C(=O)[O-]>>COC(=O)c1ccc([N+](=O)[O-])cc1C(=O)N1CCN(c2ccc(C(C)=O)cc2F)CC1 -US20070287717A1,2,COc1ccccc1C(=O)Cl.N#Cc1sc(-c2ccc(F)cc2)cc1N>>COc1ccccc1C(=O)Nc1cc(-c2ccc(F)cc2)sc1C#N -US08501732B2,1,C1COCCN1.O=C(NCc1cn(-c2ccccc2F)c2cc(F)ccc2c1=O)c1ccc(Cl)nc1>>O=C(NCc1cn(-c2ccccc2F)c2cc(F)ccc2c1=O)c1ccc(N2CCOCC2)nc1 -US08586571B2,6,CC(C)(C)OC(=O)N1CC(Sc2ccccc2C(C)(C)C)C1>>CC(C)(C)c1ccccc1SC1CNC1 -US20070072920A1,7,COc1cc(C(=O)c2ccccc2)c(OC)cc1C[C@@H](C)NC(=O)C(F)(F)F>>COc1cc(C[C@@H](C)NC(=O)C(F)(F)F)c(OC)cc1Cc1ccccc1 -US20080249146A1,1,CCOC(=O)CN.O=C1CCCCC1>>CCOC(=O)CNC1CCCCC1 -US04835165,2,CS(=O)(=O)Cl.Cc1cnc(N2CCC(c3ccc(N)cc3)CC2)n1C>>Cc1cnc(N2CCC(c3ccc(NS(C)(=O)=O)cc3)CC2)n1C -US20090264445A1,6,COC(=O)[C@H](CC(C)C)N1CC(Oc2cccc3c2CCCC3)=CC1=O>>CC(C)C[C@@H](C(=O)O)N1CC(Oc2cccc3c2CCCC3)=CC1=O -US05750696,2,N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1.O=C(Cl)N1CCCCC1>>O=C(OCc1ccccc1)[C@H](Cc1ccccc1)NC(=O)N1CCCCC1 -US20150119390A1,7,OCc1cccc(C2=CCOCC2)c1>>OCc1cccc(C2CCOCC2)c1 -US05543550,7,CCCOC(=O)c1cc(F)ccc1[N+](=O)[O-]>>CCCOC(=O)c1cc(F)ccc1N -US20140200227A1,2,CC(=O)OC1CCc2c1ncc(N)c2N1CCC[C@H](NC(=O)OC(C)(C)C)C1.CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)O>>CC(=O)OC1CCc2c1ncc(NC(=O)c1nc(-c3c(F)cccc3F)sc1NC(=O)OC(C)(C)C)c2N1CCC[C@H](NC(=O)OC(C)(C)C)C1 -US20030186970A1,1,C=O.CC(C)Oc1cc(C(F)(F)F)c2cc3c(cc2n1)SCCN3>>CC(C)Oc1cc(C(F)(F)F)c2cc3c(cc2n1)SCCN3C -US07737166B2,1,CCCC[Sn](CCCC)(CCCC)C1=CC(NC(=O)OC(C)(C)C)CC1.CI>>CCCC[Sn](CCCC)(CCCC)C1=CC(N(C)C(=O)OC(C)(C)C)CC1 -US20040157866A1,2,Cc1cc2c(c(C)c1N)CCN2C(=O)Cc1ccccn1.O=C(Cl)c1ccccc1-c1ccc(C(F)(F)F)cc1>>Cc1cc2c(c(C)c1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1)CCN2C(=O)Cc1ccccn1 -US08609622B2,3,O=C(Cl)c1cc(Br)ccc1Cl.c1ccc2c(c1)CCO2>>O=C(c1ccc2c(c1)CCO2)c1cc(Br)ccc1Cl -US04361559,6,CCCCSC1(SCC)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](OC(C)=O)C[C@@]21C>>CCCCSC1(SCC)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C -US20150152047A1,6,CCOC(=O)c1cc(Cl)c(N2CCN(C(=O)OC(C)(C)C)CC2)c(OC(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCN(c2c(Cl)cc(C(=O)O)cc2OC(F)(F)F)CC1 -US05208250,3,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.O=C1CSC(=O)N1>>CC(C)(C)c1cc(C=C2SC(=O)NC2=O)cc(C(C)(C)C)c1O -US20030180662A1,2,C=CC(=O)Cl.CCC(O)(CC)C12CC3CC(CC(O)(C3)C1)C2>>C=CC(=O)OC(CC)(CC)C12CC3CC(CC(O)(C3)C1)C2 -US06300363B1,2,CC(=O)CC(=O)OC(C)(C)C.Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12>>CC(=O)CC(=O)Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12 -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(O)COCc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)COCc4ccccc4)cc3)cc2)CC1 -US20070259951A1,3,COC(=O)c1cc(NS(C)(=O)=O)ccc1Br.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)c1cc(NS(C)(=O)=O)ccc1-c1ccc(C(F)(F)F)cc1 -US20130303524A1,4,CC(=O)C(C)(C)N1CCCS1(=O)=O.C[S+](C)(C)=O>>CC1(C(C)(C)N2CCCS2(=O)=O)CO1 -US20120184542A1,2,CCOC(=O)c1ccc(Cl)c(N)c1.COc1ncc2cc(C(=O)O)c(=O)[nH]c2n1>>CCOC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(OC)nc3[nH]c2=O)c1 -US08431563B2,7,O=[N+]([O-])c1ccccc1S(=O)(=O)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1>>Nc1ccccc1S(=O)(=O)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1 -US20150038438A1,6,COC(=O)c1cc2c(n(Cc3ccc(OC)cc3OC)c1=O)-c1cc3cc(CO)n(C)c3cc1CCC2>>COc1ccc(Cn2c3c(cc(C(=O)O)c2=O)CCCc2cc4c(cc2-3)cc(CO)n4C)c(OC)c1 -US20080188528A1,2,COC(=O)[C@@H](N)CCCCNC(=O)OC(C)(C)C.O=C(O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O>>COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O -US07652015B2,1,C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](C)CN1.Cc1cc([N+](=O)[O-])cnc1Cl>>Cc1cc([N+](=O)[O-])cnc1N1C[C@H](C)N(C(=O)OC(C)(C)C)C[C@H]1C -US08450307B2,2,CCc1c(CNC)oc2ccccc12.O=C(O)C=Cc1cnc2c(c1)CNCC(=O)N2>>CCc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CNCC(=O)N3)oc2ccccc12 -US20120028918A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.NC(=O)Cc1ccc(Br)cn1>>CC1(C)OB(c2ccc(CC(N)=O)nc2)OC1(C)C -US20150080393A1,3,CC=C[Sn](CCCC)(CCCC)CCCC.CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(Cl)cc4-c4cccc(S(C)(=O)=O)c4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OC(C)(C)C>>C/C=C/c1ccc([C@@H](Oc2cc(N3CCC4(CC3)C[C@@H](C(=O)OCC)N(C(=O)OC(C)(C)C)C4)nc(N)n2)C(F)(F)F)c(-c2cccc(S(C)(=O)=O)c2)c1 -US04425274,7,C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3C(=O)CC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@@]1(C)CC[C@@H](O)CC1C[C@@H]3O -US06573286B1,3,C[C@@H]1OC(c2c(F)cccc2F)=N[C@@H]1c1ccc(Br)cc1.OB(O)c1ccc(OC(F)(F)F)cc1>>C[C@@H]1OC(c2c(F)cccc2F)=N[C@@H]1c1ccc(-c2ccc(OC(F)(F)F)cc2)cc1 -US06242644B1,3,C#C[Si](C)(C)C.CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(Br)cc(CO)c1>>CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(C#C[Si](C)(C)C)cc(CO)c1 -US08969552B2,2,CCC(=O)OC(=O)CC.N[C@@H]1CCc2ccccc2C1>>CCC(=O)N[C@@H]1CCc2ccccc2C1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.O=S1(=O)c2ccccc2-c2ccc(I)cc21>>CC(C)(C)OC(=O)COc1ccc(Cl)cc1C#Cc1ccc2c(c1)S(=O)(=O)c1ccccc1-2 -US20040024047A1,2,CC(=O)Cl.NC(=O)c1cc(-c2ccc(F)cc2)sc1N>>CC(=O)Nc1sc(-c2ccc(F)cc2)cc1C(N)=O -US20090062277A1,1,Clc1cc(Br)cnc1Cl.OC1(c2ccccn2)CCNCC1>>OC1(c2ccccn2)CCN(c2ncc(Br)cc2Cl)CC1 -US20100041891A1,2,COCCC(=O)O.Nc1cccc(Br)c1>>COCCC(=O)Nc1cccc(Br)c1 -US05371231,3,CCOP(=O)(CC#N)OCC.O=Cc1ccc(Cl)c(C(F)(F)F)c1>>N#CC=Cc1ccc(Cl)c(C(F)(F)F)c1 -US20080262050A1,6,COc1ccc2c(c1)CC(OC(C)=O)CC2>>CC(=O)OC1CCc2ccc(O)cc2C1 -US20110086834A1,4,C=C(C(=O)OC)c1ccc(Br)cc1[N+](=O)[O-].O=C(OO)c1cccc(Cl)c1>>COC(=O)C1(c2ccc(Br)cc2[N+](=O)[O-])CO1 -US20100298221A1,1,NC(=O)c1c(C(F)(F)F)cc(-c2cc(F)cc(F)c2)nc1Cl.Oc1ccccc1Cl>>NC(=O)c1c(C(F)(F)F)cc(-c2cc(F)cc(F)c2)nc1Oc1ccccc1Cl -US20070270421A1,7,O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ccn1)N1CCC(CN2CCCC2)CC1>>Nc1ccc(Oc2ccnc(NC(=O)N3CCC(CN4CCCC4)CC3)c2)c(F)c1 -US20120277237A1,3,C#CCCc1nc2ncccc2o1.Ic1ccccn1>>C(#Cc1ccccn1)CCc1nc2ncccc2o1 -US07618978B2,6,CCCN(C)C(=O)c1cc(C(=O)OC)cc(N2CCCC2=O)c1>>CCCN(C)C(=O)c1cc(C(=O)O)cc(N2CCCC2=O)c1 -US20050267095A1,6,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(OCCCN3CCCC3)cc2)CC1>>N#CC1(c2ccc(OCCCN3CCCC3)cc2)CCNCC1 -US05639760,2,CCOC(=O)C1=C(O)CCn2c1nc1ccccc12.Nc1ccncc1>>O=C(Nc1ccncc1)C1=C(O)CCn2c1nc1ccccc12 -US20130184272A1,9,CCCOc1sc(C(=O)O)c2c1-c1c(cnn1C)CC2.N>>CCCOc1sc(C(N)=O)c2c1-c1c(cnn1C)CC2 -US20100273806A1,3,C#CC1CC1.CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(Br)cc(OC(F)(F)F)c4)n3)cc21>>CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(C#CC5CC5)cc(OC(F)(F)F)c4)n3)cc21 -US08841463B2,6,CC(C)C[C@@H](/C=C/C(=O)N1CCc2ccccc21)NC(=O)C1(NC(=O)OC(C)(C)C)CCOCC1>>CC(C)C[C@@H](/C=C/C(=O)N1CCc2ccccc21)NC(=O)C1(N)CCOCC1 -US06344559B1,1,CCOC(=O)CCl.O=c1[nH]c(=O)c2ccc(Cl)cc2[nH]1>>CCOC(=O)Cn1c(=O)[nH]c(=O)c2ccc(Cl)cc21 -US05004747,6,CCOC(=O)CC(O)CC(O)/C=C/c1c(-c2ccccc2)c2ccccc2c(=O)n1C>>Cn1c(/C=C/C(O)CC(O)CC(=O)O)c(-c2ccccc2)c2ccccc2c1=O -US20110152316A1,3,BrCc1ccccc1.Cc1cc(C=O)cc(B(O)O)c1>>Cc1cc(C=O)cc(Cc2ccccc2)c1 -US06162610,7,COc1ccc2c(=O)c3ccccc3oc2c1>>COc1ccc2c(c1)Oc1ccccc1C2 -US20050154042A1,2,CC(C)n1c(C=O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)O.Nc1ccccc1>>CC(C)n1c(C=O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)Nc1ccccc1 -US04772752,7,CC(=O)c1ccccc1>>C[C@H](O)c1ccccc1 -US20130203732A1,1,Cn1ncc([N+](=O)[O-])c1Cl.O[C@H]1CNC[C@@H]1O>>Cn1ncc([N+](=O)[O-])c1N1C[C@H](O)[C@@H](O)C1 -US07122662B2,6,CCOC(=O)CN(CC(OCC)OCC)C(=O)OCc1ccccc1>>CCOC(=O)CN(CC=O)C(=O)OCc1ccccc1 -US05262436,6,Cc1ccc(CSC[C@H](N)C(=O)NC(=O)OC(C)(C)C)cc1>>Cc1ccc(CSC[C@H](N)C(N)=O)cc1 -US20120053171A1,2,COc1nc(Br)ccc1N.O=CO>>COc1nc(Br)ccc1NC=O -US04332808,1,C=CCBr.OC1(c2cccc3[nH]ccc23)CCCNC1>>C=CCN1CCCC(O)(c2cccc3[nH]ccc23)C1 -US06218156B1,7,CCOC(=O)CC(=O)CCl>>CCOC(=O)C[C@H](O)CCl -US20150225373A1,2,NCCN1CCOCC1.Nc1cc(Br)cc(C(=O)O)c1>>Nc1cc(Br)cc(C(=O)NCCN2CCOCC2)c1 -US05597823,1,CC(C)I.CCOC(=O)c1nc2ccsc2nc1N>>CCOC(=O)c1nc2ccsc2nc1NC(C)C -US20070015743A1,2,CC(C)(O)C(=O)O.Clc1cc(Nc2ncnc3cccc(OC[C@H]4CCCN4)c23)ccc1OCc1ccccn1>>CC(C)(O)C(=O)N1CCC[C@@H]1COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12 -US20100068204A1,1,Nc1cccc(Oc2cc(=O)[nH]c3ccccc23)c1.O=Cc1cccnc1>>O=c1cc(Oc2cccc(NCc3cccnc3)c2)c2ccccc2[nH]1 -US06559167B1,2,CC(=O)Nc1nc(C)c(S(=O)(=O)Cl)s1.COc1ccc2[nH]c(S(=O)Cc3ncc(C)c(OC)c3C)nc2c1>>COc1ccc2c(c1)nc(S(=O)Cc1ncc(C)c(OC)c1C)n2S(=O)(=O)c1sc(NC(C)=O)nc1C -US20100298287A1,1,CC(C)(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl.CI>>COC(C)(C)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl -US20140113005A1,4,CCS(=O)(=O)N1CCN(c2cnc(N)c(C(=O)O)n2)CC1.CNc1ccccc1N>>CCS(=O)(=O)N1CCN(c2cnc(N)c(-c3nc4ccccc4n3C)n2)CC1 -US20100035917A1,3,C#CCO.Cc1ccc(S(=O)(=O)n2c(I)cc3c(Br)ccnc32)cc1>>Cc1ccc(S(=O)(=O)n2c(C#CCO)cc3c(Br)ccnc32)cc1 -US20090048269A1,1,Cc1cc(Oc2ccnc(Cl)c2)c(-c2ccccn2)nc1C.N#Cc1cccc(N)c1>>Cc1cc(Oc2ccnc(Nc3cccc(C#N)c3)c2)c(-c2ccccn2)nc1C -US20090023734A1,3,C#C[Si](C)(C)C.COC(=O)c1ccc(Br)cc1>>COC(=O)c1ccc(C#C[Si](C)(C)C)cc1 -US06933322B2,3,O=S(=O)(Nc1ccc2c(OCc3ccc(Br)cc3)cccc2c1)C(F)(F)F.OB(O)c1ccc(F)cc1>>O=S(=O)(Nc1ccc2c(OCc3ccc(-c4ccc(F)cc4)cc3)cccc2c1)C(F)(F)F -US20080188452A1,1,CCOC(=O)CCCBr.COC(=O)c1ccccc1O>>CCOC(=O)CCCOc1ccccc1C(=O)OC -US20050004134A1,1,CI.CNC(=O)c1nc(-c2ccccc2)c(-c2ccc(=O)n(C(C)C)n2)s1>>CC(C)n1nc(-c2sc(C(=O)N(C)C)nc2-c2ccccc2)ccc1=O -US20110137063A1,2,O=S(=O)(Cl)c1cccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1.OCCOc1ccccc1>>O=S(=O)(OCCOc1ccccc1)c1cccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1 -US20090264482A1,3,N#Cc1ccc2c(cc(C3CC3)n2Cc2ccc(Br)o2)c1C(F)(F)F.OB(O)c1cccc(C(F)(F)F)c1>>N#Cc1ccc2c(cc(C3CC3)n2Cc2ccc(-c3cccc(C(F)(F)F)c3)o2)c1C(F)(F)F -US06265415B1,1,Cc1cccc(C)c1CCl.Cc1nc2c(O)cccn2c1CO>>Cc1cccc(C)c1COc1cccn2c(CO)c(C)nc12 -US20150231119A1,7,CCOC(=O)c1cc2cc(Cl)ncc2n1CCCCF>>OCc1cc2cc(Cl)ncc2n1CCCCF -US06329373B1,6,COC(=O)CC1CCC(C(C)(C)C)CC1>>CC(C)(C)C1CCC(CC(=O)O)CC1 -US05506256,6,O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)OCC12CC3CC(CC(C3)C1)C2>>O=C(O)[C@@H]1CCCN1C(=O)OCC12CC3CC(CC(C3)C1)C2 -US04022794,6,COC(=O)CCCCCCC1SCC(=O)N1CCC1(O)CCCCC1>>O=C(O)CCCCCCC1SCC(=O)N1CCC1(O)CCCCC1 -US20120202815A1,6,CC(=O)NCc1cc(-c2cc[nH]n2)ccc1Cl>>NCc1cc(-c2cc[nH]n2)ccc1Cl -US08273740B2,1,BrCCOc1ccccc1.CC(C)(C)OC(=O)Cn1c(S)nc2ccccc21>>CC(C)(C)OC(=O)Cn1c(SCCOc2ccccc2)nc2ccccc21 -US20120214802A1,1,CI.COC(=O)c1cc(NS(C)(=O)=O)cc(C(=O)OC)c1>>COC(=O)c1cc(C(=O)OC)cc(N(C)S(C)(=O)=O)c1 -US20110263571A1,2,O=C(Cl)c1ccc(I)cc1.c1nc(N2CCNCC2)c(C2CC2)cc1C1CC1>>O=C(c1ccc(I)cc1)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1 -US08093239B2,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C(OCc1ccccc1)N1CCNCC1>>CC(C)(C)OC(=O)N1CCC(N2CCN(C(=O)OCc3ccccc3)CC2)CC1 -US20130040930A1,1,O=C(c1ccc(Br)cn1)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1.O=S1(=O)CCCN1>>O=C(c1ccc(N2CCCS2(=O)=O)cn1)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1 -US20130196982A1,3,CCNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.C[C@H]1COCCN1c1nc(Cl)cc(Cl)n1>>CCNC(=O)Nc1ccc(-c2cc(Cl)nc(N3CCOC[C@@H]3C)n2)cc1 -US20080112899A1,2,CC(C)C(C(=O)Cl)C(C)C.N#Cc1ccc(N)cc1>>CC(C)C(C(=O)Nc1ccc(C#N)cc1)C(C)C -US20110263584A1,3,CC(C)[C@@]1(CC(C)(C)O)CCN([C@@H](C)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)C(=O)O1.O=C(O)c1ncc(Br)cn1>>CC(C)[C@@]1(CC(C)(C)O)CCN([C@@H](C)c2ccc(-c3cnc(C(=O)O)nc3)cc2)C(=O)O1 -US20150239856A1,6,COC(=O)c1ccc(-c2nc3cc([N+](=O)[O-])c(O)cc3o2)cc1>>O=C(O)c1ccc(-c2nc3cc([N+](=O)[O-])c(O)cc3o2)cc1 -US04591458,1,CC(C)(C)OC(=O)CN1C(=O)[C@@H](N)COc2ccccc21.CCOC(=O)C(=O)CCCCCC1CCN(C(=O)OCc2ccccc2)CC1>>CCOC(=O)[C@@H](CCCCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@H]1COc2ccccc2N(CC(=O)OC(C)(C)C)C1=O -US05246961,1,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](Br)SC[C@H]1OC(C)=O.Sc1ccccc1>>CC(=O)O[C@H]1[C@H](Sc2ccccc2)SC[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US07238714B2,6,COC(=O)c1cc(Cl)ccc1Oc1cncc(F)c1>>O=C(O)c1cc(Cl)ccc1Oc1cncc(F)c1 -US20070185086A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=C1CCOCC1>>CCOC(=O)C=C1CCOCC1 -US05696267,8,CON=C(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCO)c1ccc(Cl)c(Cl)c1>>CON=C(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CC=O)c1ccc(Cl)c(Cl)c1 -US20140163033A1,6,COC(=O)[C@@H]1CC(F)(F)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1C(=O)O -US05114940,4,CCOC(=O)CC(=O)C(F)(F)F.Nc1ccccc1>>Oc1cc(C(F)(F)F)c2ccccc2n1 -US05071863,7,Cc1c(F)c([N+](=O)[O-])cc2oc(=O)[nH]c12>>Cc1c(F)c(N)cc2oc(=O)[nH]c12 -US20110257208A1,1,CCc1nc(C)c(C=O)s1.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>CCc1nc(C)c(CN2Cc3ncnc(Nc4cnc5ccccc5c4)c3C2)s1 -US20110166121A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C(N)Cc1ccc(O)cc1>>COC(=O)C(Cc1ccc(O)cc1)NC(=O)OC(C)(C)C -US20040254179A1,1,Cc1nc(C#Cc2cccc(C#N)c2)c[nH]1.Fc1cncc(F)c1>>Cc1nc(C#Cc2cccc(C#N)c2)cn1-c1cncc(F)c1 -US08846660B2,7,CCC[C@@H](NC(=O)N1CC(=NOCC)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c([N+](=O)[O-])c1>>CCC[C@@H](NC(=O)N1CC(=NOCC)NC[C@@H](Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 -US20150031627A1,1,CCOC(=O)CN1C[C@@H](C(=O)N(c2cccc(F)c2)C(C(=O)NC2CC(F)(F)C2)c2ccccc2Cl)NC1=O.N#Cc1ccnc(Br)c1>>CCOC(=O)CN1C[C@@H](C(=O)N(c2cccc(F)c2)C(C(=O)NC2CC(F)(F)C2)c2ccccc2Cl)N(c2cc(C#N)ccn2)C1=O -US20090054460A1,6,Cc1ccc(S(=O)(=O)N2CCNC(=O)[C@H]2CC(=O)NC2CCCc3c2cnn3CCO[Si](C)(C)C(C)(C)C)cc1>>Cc1ccc(S(=O)(=O)N2CCNC(=O)[C@H]2CC(=O)NC2CCCc3c2cnn3CCO)cc1 -US20090018156A1,3,CCn1cc(Br)c(-c2cccc([N+](=O)[O-])c2)n1.Cc1ccc(S(=O)(=O)n2ccc3c(B4OC(C)(C)C(C)(C)O4)ccnc32)cc1>>CCn1cc(-c2ccnc3c2ccn3S(=O)(=O)c2ccc(C)cc2)c(-c2cccc([N+](=O)[O-])c2)n1 -US07291634B2,7,O=Cc1ccc(-n2nccn2)cc1>>OCc1ccc(-n2nccn2)cc1 -US05703243,2,NC[C@@H]1C[C@H](S)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1.NS(=O)(=O)Cl>>NS(=O)(=O)NC[C@@H]1C[C@H](S)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1 -US20060223826A1,2,C[C@@H](c1c[nH]c2ccccc12)[C@@H](N)C(=O)Nc1cccc(CN(C)C)c1.O=C(O)C1CCN(c2ccccc2)CC1>>C[C@@H](c1c[nH]c2ccccc12)[C@@H](NC(=O)C1CCN(c2ccccc2)CC1)C(=O)Nc1cccc(CN(C)C)c1 -US20130196974A1,1,CNCCN.Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(Cl)c2c1>>CNCCNc1cc(N2CCS(=O)(=O)c3ccccc3C2)nc2ccc(C)cc12 -US08088767B2,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(F)ccc1[N+](=O)[O-]>>Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-] -US20120114765A1,2,NC1CCCCC1.O=C(Cl)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(NC1CCCCC1)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US07851473B2,1,CC(C)(C)OC(=O)N1CCNCC1.Fc1ccc(-c2csc(Br)n2)cc1>>CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccc(F)cc3)cs2)CC1 -US07544812B2,7,CCCN1C(=O)N(Cc2ccc(C)cc2)C(=O)C1CCCc1ccc(OC)cc1>>CCCN1C(=O)N(Cc2ccc(C)cc2)CC1CCCc1ccc(OC)cc1 -US07932281B2,2,CC(C)(C)OC(=O)NCc1ccc(C(=O)O)cc1.CCCN(CCC)Cc1ccc(N)cc1>>CCCN(CCC)Cc1ccc(NC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)cc1 -US05216173,1,N#CBr.O=C1NC(=O)[C@H]2CC=CC[C@@H]12>>N#CN1C(=O)[C@@H]2CC=CC[C@@H]2C1=O -US07393569B2,2,C=CC(=O)O.CC(C(=O)O)c1ccc(OCCCCCCO)cc1>>C=CC(=O)OCCCCCCOc1ccc(C(C)C(=O)O)cc1 -US04960796,2,CCC(C)Oc1ccc(OCCN)cc1.O=C(Cl)C1CC1>>CCC(C)Oc1ccc(OCCNC(=O)C2CC2)cc1 -US05693643,9,CC1(C)C2CC[C@@]1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(=O)C2.NO>>CC1(C)C2CC[C@@]1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(=NO)C2 -US20150018341A1,3,CCC(=O)c1ccc2c(c1)ncn2C.O=C(c1ccc(O)cc1)c1ccc(OCCCl)cc1>>CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCCl)cc1)c1ccc2c(c1)ncn2C -US06599918B2,2,CO.O=C(O)c1ccc(-c2cccnc2)cc1>>COC(=O)c1ccc(-c2cccnc2)cc1 -US20060063791A1,1,CI.O=C1Nc2ccc([N+](=O)[O-])cc2C1=O>>CN1C(=O)C(=O)c2cc([N+](=O)[O-])ccc21 -US05872138,1,BrCC1CCCCC1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCC2CCCCC2)cc1 -US08063038B2,1,COC(=O)CBr.O=C1CNc2c(F)cccc2N1>>COC(=O)CN1C(=O)CNc2c(F)cccc21 -US20130197012A1,2,CCOC(=O)c1cccc(-c2cc3c(C(=O)NC)c(-c4ccc(F)cc4)oc3cc2N)c1.CS(=O)(=O)Cl>>CCOC(=O)c1cccc(-c2cc3c(C(=O)NC)c(-c4ccc(F)cc4)oc3cc2NS(C)(=O)=O)c1 -US20120202785A1,7,O=[N+]([O-])c1ncccc1Nc1ccccc1>>Nc1ncccc1Nc1ccccc1 -US20100069629A1,3,COC(=O)c1cccc(B(O)O)c1.Clc1nc(N2CCOCC2)nc2c1CCN2c1cccnc1>>COC(=O)c1cccc(-c2nc(N3CCOCC3)nc3c2CCN3c2cccnc2)c1 -US20120058988A1,9,COC(=O)c1cc(-c2cccc(C(F)(F)F)c2)nc2c1[nH]c1cc([N+](=O)[O-])ccc12.N>>NC(=O)c1cc(-c2cccc(C(F)(F)F)c2)nc2c1[nH]c1cc([N+](=O)[O-])ccc12 -US08003662B2,2,CN1CCN(CC#Cc2cc3nccc(Oc4ccc(N)cc4F)c3s2)CC1.O=C(O)c1cccn(-c2ccc(F)cc2)c1=O>>CN1CCN(CC#Cc2cc3nccc(Oc4ccc(NC(=O)c5cccn(-c6ccc(F)cc6)c5=O)cc4F)c3s2)CC1 -US06211199B1,1,COC(=O)c1cc(CCl)ccc1OC.c1c[nH]nn1>>COC(=O)c1cc(Cn2ccnn2)ccc1OC -US08173813B2,7,O=C1CCc2cc([N+](=O)[O-])ccc2N1CCCN1CCCC1>>Nc1ccc2c(c1)CCC(=O)N2CCCN1CCCC1 -US05962450,1,CCCNCCC.O=C1c2c(Cl)cccc2-n2cnc(-c3nc(CCl)cs3)c2[C@@H]2CCCN12>>CCCN(CCC)Cc1csc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2c(Cl)cccc2-3)n1 -US20100317657A1,3,Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21.OB(O)c1cncnc1>>Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(-c4cncnc4)cc3c21 -US06329389B1,6,CCOC(=O)C1Cc2ccc(Cl)cc2NC1=O>>O=C(O)C1Cc2ccc(Cl)cc2NC1=O -US08399451B2,6,CCCc1c(-c2nc(-c3ccc(C(O)CN4CC(C(=O)OC(C)(C)C)C4)cc3)no2)noc1-c1ccccc1>>CCCc1c(-c2nc(-c3ccc(C(O)CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 -US20070185119A1,1,Cc1nc(Cl)nc2ccccc12.O=C(N[C@H]1CCC[C@H](NC(=O)OCc2ccccc2)C1)OCc1ccccc1>>Cc1nc(N(C(=O)OCc2ccccc2)[C@H]2CCC[C@H](NC(=O)OCc3ccccc3)C2)nc2ccccc12 -US20130244993A1,3,CNC(=O)C1(c2ccc(Br)cn2)CC1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>CNC(=O)C1(c2ccc(-c3ccc([C@H](C)N4CC[C@](CC(C)(C)O)(c5ccccc5)OC4=O)cc3)cn2)CC1 -US20140350002A1,7,CN1c2nc(C3=CC4CNCC4C3)ccc2N(CC2CC2(F)F)S1(=O)=O>>CN1c2nc(C3CC4CNCC4C3)ccc2N(CC2CC2(F)F)S1(=O)=O -US08889702B2,1,CS(=O)(=O)OC1CC2(CCN(c3ccc(-c4ccc(F)cc4)cn3)CC2)C1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC1CC2(CCN(c3ccc(-c4ccc(F)cc4)cn3)CC2)C1 -US05221629,1,O=C1CCN(C2(c3ccccc3)CCCCC2)CC1.[NH4+]>>NC1CCN(C2(c3ccccc3)CCCCC2)CC1 -US20100234389A1,3,CC(C)(C)OC(=O)N1CCN(c2ccnc(Cl)n2)CC1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2ccnc(-c3ccccc3)n2)CC1 -US05646171,6,CCCCc1nc(CO)c(C(=O)OC)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCCc1nc(CO)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US20120058989A1,3,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1C=O.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CO/C=C\C1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C -US07977371B2,1,NC(=O)Nc1[nH]c(-c2ccc(C=O)cc2)cc1C(N)=O.OCCNCc1ccccc1>>NC(=O)Nc1[nH]c(-c2ccc(CN(CCO)Cc3ccccc3)cc2)cc1C(N)=O -US20140336177A1,6,Cc1c([C@@H]2CN3CCN(C(=O)OCc4ccccc4)C[C@H]3CN2C(=O)OC(C)(C)C)ccc(F)c1C#N>>Cc1c([C@@H]2CN3CCNC[C@H]3CN2C(=O)OC(C)(C)C)ccc(F)c1C#N -US20080221096A1,1,CC1(C)Cc2c(c(N3CCOCC3)nc3oc4c(Cl)ncnc4c23)CO1.NCCN1CCOCC1>>CC1(C)Cc2c(c(N3CCOCC3)nc3oc4c(NCCN5CCOCC5)ncnc4c23)CO1 -US09045475B2,1,NC1CN(C2CCOC2)C1.NS(=O)(=O)c1ccc(F)c([N+](=O)[O-])c1>>NS(=O)(=O)c1ccc(NC2CN(C3CCOC3)C2)c([N+](=O)[O-])c1 -US08119663B2,2,NC1CCNC1.O=C(Cl)N1CC(c2ccc(OC(F)(F)F)cc2)CC(c2nc(-c3cccc(F)c3)no2)C1>>NC1CCN(C(=O)N2CC(c3ccc(OC(F)(F)F)cc3)CC(c3nc(-c4cccc(F)c4)no3)C2)C1 -US20140155407A1,3,Brc1ccc(Cn2ccnc2)cn1.OB(O)c1cncnc1>>c1cn(Cc2ccc(-c3cncnc3)nc2)cn1 -US07910595B2,2,Cc1cc(N)sn1.O=C(Nc1ccc(Sc2ccc(C(=O)Cl)cc2[N+](=O)[O-])cc1)OCC1c2ccccc2-c2ccccc21>>Cc1cc(NC(=O)c2ccc(Sc3ccc(NC(=O)OCC4c5ccccc5-c5ccccc54)cc3)c([N+](=O)[O-])c2)sn1 -US20150210720A1,1,CC(C)(C)[Si](C)(C)OCCBr.O=[N+]([O-])c1ccc2[nH]ncc2c1>>CC(C)(C)[Si](C)(C)OCCn1ncc2cc([N+](=O)[O-])ccc21 -US20060094768A1,7,O=Cc1ccc(-c2ccc(C(F)(F)F)cc2)s1>>OCc1ccc(-c2ccc(C(F)(F)F)cc2)s1 -US08952010B2,1,CC(C)(C)OC(=O)N[C@H]1CNC(=O)C1.O=C1COc2ccc(Br)cc2N1COCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H]1CC(=O)N(c2ccc3c(c2)N(COCc2ccccc2)C(=O)CO3)C1 -US06444670B2,6,COC(=O)CNc1cc(-c2c3ccccc3c(Br)c3sc(C)c(C)c23)cc(Br)c1OC>>COc1c(Br)cc(-c2c3ccccc3c(Br)c3sc(C)c(C)c23)cc1NCC(=O)O -US08501732B2,1,NC1CCOCC1.O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(Cl)nc1>>O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(NC2CCOCC2)nc1 -US08148408B2,1,Clc1cncc(Cl)n1.OCc1ccc(F)cc1>>Fc1ccc(COc2cncc(Cl)n2)cc1 -US07897607B2,3,Cc1cc(C)c(B(O)O)c(C)c1.OCc1cccc(Br)n1>>Cc1cc(C)c(-c2cccc(CO)n2)c(C)c1 -US05098466,9,CC(=O)c1cnc(Cl)nc1C(=O)O>>CC(=O)c1cncnc1C(=O)O -US07648985B2,6,N#Cc1ccc2c(c1)CCN2C(=O)C(F)(F)F>>N#Cc1ccc2c(c1)CCN2 -US06277877B1,2,N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC(O)CC1.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>O=C(N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC(O)CC1)c1cc2cc(Cl)ccc2[nH]1 -US08383596B2,6,CC(C)(C)OC(=O)CC1(O)CN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CC(O)(CC(=O)O)C1 -US05491167,1,CCC(Oc1ccccc1F)C(=O)O.C[C@H]1C=CC2=C[C@@H](C(C)(C)C)C[C@H](O)[C@@H]2[C@@]1(CC[C@@H]1C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O1)O[SiH](C)C>>CCC(Oc1ccccc1F)C(=O)O[C@H]1C[C@H](C(C)(C)C)C=C2C=C[C@H](C)[C@](CC[C@@H]3C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O3)(O[SiH](C)C)[C@H]21 -US08153814B2,1,CC(C)(C)OC(=O)N(c1cscn1)S(=O)(=O)c1ccc(F)c(C#N)c1.Oc1ccc(Cl)cc1I>>CC(C)(C)OC(=O)N(c1cscn1)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2I)c(C#N)c1 -US07989442B2,2,CC(=O)Cl.N[C@@H]1CCCN2c3cc(Br)c(F)cc3Oc3cccc(F)c3[C@@H]12>>CC(=O)N[C@@H]1CCCN2c3cc(Br)c(F)cc3Oc3cccc(F)c3[C@@H]12 -US06140330,3,COc1cc(CCC(=O)Nc2nc3ccccc3s2)ccc1C(=O)CP(=O)(OC)OC.O=CC(=O)O>>COc1cc(CCC(=O)Nc2nc3ccccc3s2)ccc1C(=O)/C=C/C(=O)O -US09029399B2,1,Fc1ccc2sc(Br)cc2c1.O=C1NCCN1c1cnccc1C1CC1>>O=C1N(c2cc3cc(F)ccc3s2)CCN1c1cnccc1C1CC1 -US20050153962A1,2,CCOC(=O)c1csc(Nc2ccc(OC)c(OC)c2)n1.O=C(Cl)c1ccccc1Cl>>CCOC(=O)c1csc(N(C(=O)c2ccccc2Cl)c2ccc(OC)c(OC)c2)n1 -US08129403B2,7,C[C@H](Nc1c(F)cc([N+](=O)[O-])c(Nc2cc(C3CC3)[nH]n2)c1F)c1ccc(F)cc1>>C[C@H](Nc1c(F)cc(N)c(Nc2cc(C3CC3)[nH]n2)c1F)c1ccc(F)cc1 -US20120040954A1,2,CNC.O=C(O)c1cc2cc(Br)ccc2[nH]1>>CN(C)C(=O)c1cc2cc(Br)ccc2[nH]1 -US20100286178A1,2,CN(C)S(=O)(=O)Cl.N#Cc1cnc2[nH]cc(C(=O)c3c(F)ccc(N)c3F)c2c1>>CN(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(C#N)cc23)c1F -US07615549B2,1,Cc1nc(NC(=O)C[C@H](CO)NC(=O)OCc2ccccc2)ccc1[N+](=O)[O-]>>Cc1nc(N2C[C@H](NC(=O)OCc3ccccc3)CC2=O)ccc1[N+](=O)[O-] -US20070249612A1,7,CC(C)C=Cc1c(C(C)C)nc(NC(C)C)c2n[nH]c(=O)n12>>CC(C)CCc1c(C(C)C)nc(NC(C)C)c2n[nH]c(=O)n12 -US08415378B2,3,COC(=O)c1ccnc(Cl)c1.FC(F)(F)c1ccccc1C[Zn+]>>COC(=O)c1ccnc(Cc2ccccc2C(F)(F)F)c1 -US20140171405A1,3,COc1cc(OC)c(F)c(B2OC(C)(C)C(C)(C)O2)c1F.Clc1ncc2cnn(C3CCCCO3)c2n1>>COc1cc(OC)c(F)c(-c2ncc3cnn(C4CCCCO4)c3n2)c1F -US20060183762A1,1,BrCC1CC1.O=c1[nH]c2cc(F)c(F)cc2c(=O)n1N(Cc1ccccc1)Cc1ccccc1>>O=c1c2cc(F)c(F)cc2n(CC2CC2)c(=O)n1N(Cc1ccccc1)Cc1ccccc1 -US20080318925A1,3,COc1ccncc1B(O)O.Nc1c(C(=O)NC2CC2)nnc2c(Br)cccc12>>COc1ccncc1-c1cccc2c(N)c(C(=O)NC3CC3)nnc12 -US07667053B2,6,COC(=O)C1(C)Cc2ccccc2O1>>CC1(C(=O)O)Cc2ccccc2O1 -US08211919B2,6,CC(=O)N1CCc2cc(-c3ccnc(N)n3)ccc21>>Nc1nccc(-c2ccc3c(c2)CCN3)n1 -US07662825B2,9,O=S(=O)(Nc1ncc(Br)nc1OCc1cccnc1)c1cccc(Cl)c1Cl.[C-]#N>>N#Cc1cnc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(OCc2cccnc2)n1 -US20090062317A1,2,Clc1ccc(-c2nc(NCCCN3CCNCC3)nc3ccccc23)cc1.O=C(Cl)c1cccc(OC(F)(F)F)c1>>O=C(c1cccc(OC(F)(F)F)c1)N1CCN(CCCNc2nc(-c3ccc(Cl)cc3)c3ccccc3n2)CC1 -US20110098311A1,9,CCOC(=O)c1c[nH]c2c(Br)ccc(OC)c2c1=O>>CCOC(=O)c1c[nH]c2cccc(OC)c2c1=O -US05368876,7,CC(C)=CCCc1ccsc1>>CC(C)CCCc1ccsc1 -US20080070948A1,1,CCC1CCCCN1.O=c1sc2ccccc2n1CCCl>>CCC1CCCCN1CCn1c(=O)sc2ccccc21 -US06822100B2,9,CCOC(=O)C1CC1C(O)c1ccc2[nH]cc(C#N)c2c1>>CCOC(=O)C1CC1Cc1ccc2[nH]cc(C#N)c2c1 -US20150038437A1,6,CCc1cc(C(=O)OC)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2c(c1)cc1n2CCC1O[Si](C)(C)C(C)(C)C>>CCc1cc(C(=O)OC)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2c(c1)cc1n2CCC1O -US20040192680A1,2,CC(C)CCSc1ccccc1/C=C/C(=O)O.NC(=O)C1CCNCC1>>CC(C)CCSc1ccccc1/C=C/C(=O)N1CCC(C(N)=O)CC1 -US20140309193A1,6,CC(C)(C)OC(=O)C(C)(C)COCCOCCOCc1ccccc1>>CC(C)(C)OC(=O)C(C)(C)COCCOCCO -US20070072859A1,6,CCC[C@@H](CCN(C)Cc1ccccc1)Oc1ccccc1C(F)(F)F>>CCC[C@@H](CCNC)Oc1ccccc1C(F)(F)F -US20030144326A1,2,COC(=O)c1sccc1S(=O)(=O)Cl.Nc1ccc(N2CCC(=O)CC2)cc1>>COC(=O)c1sccc1S(=O)(=O)Nc1ccc(N2CCC(=O)CC2)cc1 -US08486962B2,7,O=[N+]([O-])c1ccc(Nc2nccs2)cc1>>Nc1ccc(Nc2nccs2)cc1 -US20130150376A1,6,C[C@H]1C[C@]2(CCN1C(=O)OCc1ccccc1)C(O)CS(=O)(=O)N2c1cccc(F)c1>>C[C@H]1C[C@]2(CCN1)C(O)CS(=O)(=O)N2c1cccc(F)c1 -US08318949B2,2,Cc1nc(N2C[C@H](C)N(Cc3ccc(F)cc3)C2=O)sc1C(=O)O.NCc1cccnc1>>Cc1nc(N2C[C@H](C)N(Cc3ccc(F)cc3)C2=O)sc1C(=O)NCc1cccnc1 -US06197770B1,6,COC(=O)C(N)(CC#Cc1ccccc1)S(=O)(=O)c1ccc(-c2ccc3c(c2)OCO3)cc1>>NC(CC#Cc1ccccc1)(C(=O)O)S(=O)(=O)c1ccc(-c2ccc3c(c2)OCO3)cc1 -US06573267B2,3,CC(=O)c1ccc[nH]1.O=C(Cl)c1ccc2ccccc2c1>>CC(=O)c1cc(C(=O)c2ccc3ccccc3c2)c[nH]1 -US04247715,1,CCOC(=O)CBr.O=C1c2c(cc(O)c(Cl)c2Cl)CC1c1ccccc1>>CCOC(=O)COc1cc2c(c(Cl)c1Cl)C(=O)C(c1ccccc1)C2 -US09073865B2,6,Cn1cc(Cl)c(=O)c(OCc2ccccc2)c1>>Cn1cc(O)c(=O)c(Cl)c1 -US04921867,2,CS(=O)(=O)Cl.Nc1cccc(Br)n1>>CS(=O)(=O)Nc1cccc(Br)n1 -US20090099175A1,7,COc1cc(C(C)=O)c([N+](=O)[O-])cc1F>>COc1cc(C(C)=O)c(N)cc1F -US07384947B2,1,CN(C)C(=S)Cl.N#Cc1cc2c(cc1O)CCCC2>>CN(C)C(=S)Oc1cc2c(cc1C#N)CCCC2 -US05597826,3,CN1CCN(c2cccc3ccc([Sn](C)(C)C)cc23)CC1.O=C(Cl)c1ccccc1>>CN1CCN(c2cccc3ccc(C(=O)c4ccccc4)cc23)CC1 -US20140057893A1,6,COC(=O)Cc1ccc(OCC[C@@H]2C[C@@H]2C2CCN(C(=O)OC3(C)CC3)CC2)cc1F>>CC1(OC(=O)N2CCC([C@H]3C[C@H]3CCOc3ccc(CC(=O)O)c(F)c3)CC2)CC1 -US04846882,9,BrC(Br)(Br)Br.O=C1C2=C(CCCC2)C(=O)N1c1cc(CO)c(Cl)cc1F>>O=C1C2=C(CCCC2)C(=O)N1c1cc(CBr)c(Cl)cc1F -US04975438,3,CCCCC/C(=C\C=O)c1cccc(F)c1.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCC/C(=C\C=C\C(=O)OC)c1cccc(F)c1 -US20110112120A9,8,CCCCc1nc(C)n(-c2cccc(C(C)O)c2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1>>CCCCc1nc(C)n(-c2cccc(C(C)=O)c2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1 -US04698340,2,CN(C)CCN.Cc1nc(-c2ccccc2)nc(-c2cccc([N+](=O)[O-])c2)c1C(=O)O>>Cc1nc(-c2ccccc2)nc(-c2cccc([N+](=O)[O-])c2)c1C(=O)NCCN(C)C -US20100298377A1,3,C#Cc1cccc(F)c1.C[Si](C)(C)CCOCn1nc(I)c2cc([N+](=O)[O-])ccc21>>C[Si](C)(C)CCOCn1nc(C#Cc2cccc(F)c2)c2cc([N+](=O)[O-])ccc21 -US20070066624A1,1,COC(=O)N1C[C@@H](CC(C)C)N(C2CCNCC2)C1=O.Cc1nc(Sc2ccc(OCC(=O)OC(C)(C)C)cc2)ccc1C=O>>COC(=O)N1C[C@@H](CC(C)C)N(C2CCN(Cc3ccc(Sc4ccc(OCC(=O)OC(C)(C)C)cc4)nc3C)CC2)C1=O -US20100076046A1,2,CN(CCNC(=O)OC(C)(C)C)[C@H]1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1.NS(=O)(=O)CCCCl>>CN(CCNC(=O)OC(C)(C)C)[C@H]1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)CCCCl)cc3n2C1 -US05654307,2,CC(=O)Cl.CSc1ncnc2cc(N)ncc12>>CSc1ncnc2cc(NC(C)=O)ncc12 -US06166226,1,Brc1c2ccccc2cc2ccccc12.OC1CCCC1>>c1ccc2c(OC3CCCC3)c3ccccc3cc2c1 -US20150175601A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(O)cc1F>>CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])c(F)c2)CC1 -US05432182,1,CCCC(=O)c1cnc2c(COC(=O)c3ccc(OC)cc3)cccc2c1Cl.Cc1cc(O)ccc1N>>CCCC(=O)c1cnc2c(COC(=O)c3ccc(OC)cc3)cccc2c1Nc1ccc(O)cc1C -US20150225371A1,6,Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4-c4ccnn4C(=O)OC(C)(C)C)CC3)n2)ccc1F>>Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4-c4ccn[nH]4)CC3)n2)ccc1F -US05110977,2,CC(C)CCC(=O)Cl.CN(C)CCO>>CC(C)CCC(=O)OCCN(C)C -US20080306067A1,1,BrCC1CC1.O=Cc1ccc(F)c(O)c1>>O=Cc1ccc(F)c(OCC2CC2)c1 -US20100056525A1,1,CN1CCN(CCCN)CC1.C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(F)c4)ccc32)sc1C(N)=O)c1ccccc1Cl>>C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(NCCCN5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl -US20080200471A1,6,O=C(OCc1ccccc1)N1CCN2CCCCC2C1>>C1CCN2CCNCC2C1 -US20090042841A1,2,COC(=O)Cl.Cc1cccc(C#CC(O)C2CCN(C(=O)OC(C)(C)C)CC2)n1>>COC(=O)OC(C#Cc1cccc(C)n1)C1CCN(C(=O)OC(C)(C)C)CC1 -US08846657B2,1,C[C@@H](N)C1CCC1.FC(F)(F)c1ccc(Cn2cnc3cc(Cl)nc(Cl)c32)cc1>>C[C@@H](Nc1nc(Cl)cc2ncn(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1 -US06531502B1,3,COc1c(C)cc(C=O)cc1C.O=C1Cc2cc(Cl)ccc2N1>>COc1c(C)cc(C=C2C(=O)Nc3ccc(Cl)cc32)cc1C -US20070049603A1,3,CCC[Mg+].CON(C)C(=O)c1sc2cnccc2c1NC(=O)OC(C)(C)C>>CCCC(=O)c1sc2cnccc2c1NC(=O)OC(C)(C)C -US08822495B2,1,BrCC1CCOCC1.O=c1c2ccc(O)cc2ccn1-c1ccc(N2CC[C@@H](N3CCCC3)C2)c(F)c1>>O=c1c2ccc(OCC3CCOCC3)cc2ccn1-c1ccc(N2CC[C@@H](N3CCCC3)C2)c(F)c1 -US07160887B1,1,CC(C)(C)OC(=O)NCc1cccc(Oc2cc(Cl)ccc2N)c1.ClCc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)NCc1cccc(Oc2cc(Cl)ccc2NCc2ccc(Cl)c(Cl)c2)c1 -US20100152183A1,3,Cc1cnc(F)cc1I.OB(O)c1ccc(Cl)cc1>>Cc1cnc(F)cc1-c1ccc(Cl)cc1 -US05316755,1,BrCCC(c1ccccc1)c1ccccc1.Oc1c(I)cc(I)cc1I>>Ic1cc(I)c(OCCC(c2ccccc2)c2ccccc2)c(I)c1 -US04363816,1,CN1CCNCC1.Cc1cn(C)c2c1N(C(=O)CCBr)c1ccccc1NC2=O>>Cc1cn(C)c2c1N(C(=O)CCN1CCN(C)CC1)c1ccccc1NC2=O -US20090233900A1,1,COC(=O)c1cc(Cl)ccc1N.O=C1CCCCC1>>COC(=O)c1cc(Cl)ccc1NC1CCCCC1 -US04239765,1,OC(CCl)(Cc1ccc(Cl)cc1)c1ccc2c(c1)Cc1cc(Cl)ccc1-2.c1c[nH]cn1>>OC(Cc1ccc(Cl)cc1)(Cn1ccnc1)c1ccc2c(c1)Cc1cc(Cl)ccc1-2 -US06583154B1,1,C1COCCN1.Cc1cc2[nH]c(C)nc(Cl)c-2n1>>Cc1cc2[nH]c(C)nc(N3CCOCC3)c-2n1 -US05395958,6,CCCC[C@H](NC(=O)OC(C)(C)C)C(O)c1cc1=O>>CCCC[C@H](N)C(O)c1cc1=O -US20090118263A1,9,COC(=O)Cc1cccc(Br)c1.[C-]#N>>COC(=O)Cc1cccc(C#N)c1 -US20120226033A1,6,CC#CCOc1ccc(C(=O)NC[C@@H](C(=O)OC)N2CCCCC2)cc1>>CC#CCOc1ccc(C(=O)NC[C@@H](C(=O)O)N2CCCCC2)cc1 -US20130197049A1,3,Clc1nccc2ccc(Br)cc12.OB(O)c1ccc2[nH]ccc2c1>>Clc1nccc2ccc(-c3ccc4[nH]ccc4c3)cc12 -US20150031685A1,7,Cc1cc(C)cc(C(=O)CBr)c1>>Cc1cc(C)cc([C@H](O)CBr)c1 -US20120136024A1,3,C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1C2CCN(CC2)C1Cc1cccnc1>>C=C1C2CCN(CC2)C1Cc1cccnc1 -US06037363,2,CC(C)C(N)C(O)C(F)(F)F.COc1ccc(C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)O)C(C)C)cc1>>COc1ccc(C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)NC(C(C)C)C(O)C(F)(F)F)C(C)C)cc1 -US20120245161A1,6,COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)OC(C)(C)C)ccc3OCC(N)=O)CC2)c2cccc(C)c21>>COCCn1cc(C(=O)N2CCC(c3cc(CN)ccc3OCC(N)=O)CC2)c2cccc(C)c21 -US20090012076A1,3,CN(C)S(=O)(=O)Cc1ccc2ccc3ncc(Cl)cc3c(=O)c2c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>CN(C)S(=O)(=O)Cc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 -US20030225082A1,1,CNN.CSc1nccc(C(=O)Cl)n1>>CSc1nccc(C(=O)N(C)N)n1 -US20100152455A1,3,O=Cc1ccc(Br)cc1O.OB(O)c1ccccc1>>O=Cc1ccc(-c2ccccc2)cc1O -US20050288273A1,1,O=C1CCCCc2cc(N3C[C@H](CO)OC3=O)ccc21.Oc1ccon1>>O=C1CCCCc2cc(N3C[C@H](COc4ccon4)OC3=O)ccc21 -US20040192728A1,2,O=C(Nc1cnc2ccccc2c1)c1ccc(N2CCNCC2)cc1.O=C(O)Cc1ccccc1>>O=C(Nc1cnc2ccccc2c1)c1ccc(N2CCN(C(=O)Cc3ccccc3)CC2)cc1 -US07759366B2,1,BrCc1ccccc1Br.CSc1ccc(N2C(=O)NC(C)(C)C2=O)cc1C(F)(F)F>>CSc1ccc(N2C(=O)N(Cc3ccccc3Br)C(C)(C)C2=O)cc1C(F)(F)F -US08222260B2,1,Clc1nc(Cl)c2[nH]cnc2n1.Nc1cccc(Cl)c1>>Clc1cccc(Nc2nc(Cl)nc3nc[nH]c23)c1 -US05234917,2,CCCCc1ncc(CC(=O)O)n1Cc1ccccc1Cl.COC(=O)CN>>CCCCc1ncc(CC(=O)NCC(=O)OC)n1Cc1ccccc1Cl -US20120122843A1,1,CNOC.O=C(Cl)c1ccc(Cl)nc1Cl>>CON(C)C(=O)c1ccc(Cl)nc1Cl -US06495546B1,6,COc1ccc2c(c1)CC(N(Cc1ccccc1)C[C@H](O)c1cccc(Cl)c1)CCC2>>COc1ccc2c(c1)CC(NC[C@H](O)c1cccc(Cl)c1)CCC2 -US20080188506A1,7,Cc1ccc(F)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1NCCC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12 -US04690942,7,O=C(c1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(F)n1cncn1>>OC(c1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(F)n1cncn1 -US20100056507A1,7,CC1(C)CCC(C)(C)c2cc(-c3nnc(NCc4ccc([N+](=O)[O-])cc4)o3)ccc21>>CC1(C)CCC(C)(C)c2cc(-c3nnc(NCc4ccc(N)cc4)o3)ccc21 -US08088925B2,2,CC(C)N1CCC(N(Cc2nccs2)S(=O)(=O)CCN)CC1.O=C(O)c1ccc(Cl)s1>>CC(C)N1CCC(N(Cc2nccs2)S(=O)(=O)CCNC(=O)c2ccc(Cl)s2)CC1 -US20110021534A1,6,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)OCc2ccccc2)cc1>>CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)O)cc1 -US20150210688A1,1,C1CNC1.COC(=O)c1ccc(C)c(-c2cnc(CCO)[nH]2)c1>>COC(=O)c1ccc(C)c(-c2cnc(CCN3CCC3)[nH]2)c1 -US05304658,8,COC1=C(C)CC(CC(C)CCO)(OC)C(C)=C1C>>COC1=C(C)CC(CC(C)CC=O)(OC)C(C)=C1C -US20150246912A1,6,CCOC(=O)Cn1ccc(C2CC2)n1>>O=C(O)Cn1ccc(C2CC2)n1 -US07196104B2,1,C1CCNC1.O=Cc1ccc(O)cc1>>Oc1ccc(CN2CCCC2)cc1 -US04532236,8,COC(=O)CCCCc1cc2c(o1)C[C@@H](OC1CCCCO1)[C@@H]2CO>>COC(=O)CCCCc1cc2c(o1)C[C@@H](OC1CCCCO1)[C@@H]2C=O -US06992209B2,2,CC(=O)O.CC(O)C(=O)O>>CC(=O)OC(C)C(=O)O -US04775691,6,CCOC(=O)C=C1c2ccccc2C=C(OC)c2sc(Cl)cc21>>COC1=Cc2ccccc2C(=CC(=O)O)c2cc(Cl)sc21 -US20030055064A1,1,C[O-].Clc1ccnc(Cl)n1>>COc1ccnc(Cl)n1 -US20100331315A1,3,Cc1cc(C=O)cc(-c2cncc(N[C@@H](C)c3ccccc3)n2)c1.O=C1CSC(=O)N1>>Cc1cc(C=C2SC(=O)NC2=O)cc(-c2cncc(N[C@@H](C)c3ccccc3)n2)c1 -US20060258740A1,3,CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1Br.COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccccc2CCC(=O)N(NC(=O)c2ccccc2)C(C)C)cc1 -US07825155B2,2,CS(=O)(=O)Cl.O=C(OCc1ccccc1)[C@@H]1C[C@H](O)C1>>CS(=O)(=O)O[C@@H]1C[C@H](C(=O)OCc2ccccc2)C1 -US20100256134A1,2,CS(N)(=O)=O.O=C(O)c1cnn2c(NCc3ccccc3)c(C(=O)N3CCC(c4ccc(Cl)cc4)CC3)cnc12>>CS(=O)(=O)NC(=O)c1cnn2c(NCc3ccccc3)c(C(=O)N3CCC(c4ccc(Cl)cc4)CC3)cnc12 -US07132421B2,3,Clc1ccccc1.O=C(Cl)CCC1CCCC1>>O=C(CCC1CCCC1)c1ccc(Cl)cc1 -US05789412,4,ClCCNCCCl.Nc1ccc2ccccc2c1>>c1ccc2cc(N3CCNCC3)ccc2c1 -US07375226B2,2,C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)O)C(F)(F)F.Clc1ccc2sc3c(c2c1)CCNC3>>C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2c(sc3ccc(Cl)cc23)C1)C(F)(F)F -US20030225131A1,7,C[Si](C)(C)CCOCn1ccc(=O)c([N+](=O)[O-])c1NCC(F)(F)c1cccc[n+]1[O-]>>C[Si](C)(C)CCOCn1ccc(=O)c(N)c1NCC(F)(F)c1cccc[n+]1[O-] -US20060074056A1,2,Nc1ccc(Oc2ccnc3ccsc23)c(F)c1.O=C(Cc1c(Cl)cccc1Cl)N=C=S>>O=C(Cc1c(Cl)cccc1Cl)NC(=S)Nc1ccc(Oc2ccnc3ccsc23)c(F)c1 -US07776897B2,2,Cc1ccccc1-c1nnc(C2(N)CCCC2)n1C.O=C=Nc1ccccc1>>Cc1ccccc1-c1nnc(C2(NC(=O)Nc3ccccc3)CCCC2)n1C -US20110257205A1,6,CCCCn1c(=O)n(CCCCC(=O)OCC)c(=O)c2[nH]c(Cl)nc21>>CCCCn1c(=O)n(CCCCC(=O)O)c(=O)c2[nH]c(Cl)nc21 -US20100210619A1,1,CCCNCC1CC1.CNS(=O)(=O)c1ccc(NC(=O)c2cc(Cl)ncn2)c(C)c1>>CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NC)cc2C)ncn1 -US20140051679A1,1,Ic1ccc(OC2CNC2)cc1.O=C1COC1>>Ic1ccc(OC2CN(C3COC3)C2)cc1 -US20100190764A1,6,CCOC(=O)C1CCN(C2CCC3(C2)C(=O)c2cc(F)ccc2Sc2ccccc23)CC1>>O=C(O)C1CCN(C2CCC3(C2)C(=O)c2cc(F)ccc2Sc2ccccc23)CC1 -US05206242,4,CC1(C)CCC(C)(C)c2cc(C(=O)CCCl)ccc21.NNc1ccc(C(=O)O)cc1>>CC1(C)CCC(C)(C)c2cc(C3=NN(c4ccc(C(=O)O)cc4)CC3)ccc21 -US20020147334A1,2,CO.COc1ccc(CC(=O)O)c(Oc2ccccc2)c1>>COC(=O)Cc1ccc(OC)cc1Oc1ccccc1 -US20120178736A1,4,Nc1ccccc1Nc1nc(N2CCOCC2)c2sc(CN3CC(N4CCOCC4)C3)cc2n1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ccccc2n1-c1nc(N2CCOCC2)c2sc(CN3CC(N4CCOCC4)C3)cc2n1 -US20030212276A1,1,COc1cc(N)cc(OC)c1OC.COc1cc2c(Cl)c(C#N)cnc2cc1F>>COc1cc2c(Nc3cc(OC)c(OC)c(OC)c3)c(C#N)cnc2cc1F -US20080176862A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1ccc(OC(F)(F)F)c(Cl)c1>>COc1ccc(OC(F)(F)F)c(B2OC(C)(C)C(C)(C)O2)c1 -US08664220B2,3,CCOC(=O)CC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(O)C/C=C/c1ccc(Cc2ccccc2)cc1>>CCOC(=O)CC1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C/C=C/c4ccc(Cc5ccccc5)cc4)cc3)cc2)CC1 -US20120282331A1,7,C[C@]12CCC(=O)C=C1CCC1C2CC[C@]2(C)C(n3cnc4ccccc43)=CCC12>>C[C@]12CC[C@H](O)C=C1CCC1C2CC[C@]2(C)C(n3cnc4ccccc43)=CCC12 -US20140100231A1,1,CCOC(=O)c1cnc(C(C)(C)C)nc1O.CI>>CCOC(=O)c1cnc(C(C)(C)C)nc1OC -US20150018377A1,6,COc1cc(Oc2ccc(NC(=O)[C@H](NC(=O)OC(C)(C)C)C(C)(C)C)cn2)ccc1C>>COc1cc(Oc2ccc(NC(=O)[C@H](N)C(C)(C)C)cn2)ccc1C -US08466289B2,6,Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2CC(OCc3ccccc3)C2)c2n(c1=O)CCS2>>Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2CC(O)C2)c2n(c1=O)CCS2 -US05616579,1,O=C(CCCCl)NC/C=C\COc1cc(CN2CCCCC2)ccn1.Sc1nc[nH]n1>>O=C(CCCSc1nc[nH]n1)NC/C=C\COc1cc(CN2CCCCC2)ccn1 -US05571921,2,Nc1ccc(F)cc1F.O=C(Cl)CBr>>O=C(CBr)Nc1ccc(F)cc1F -US20150158882A1,7,CC(C)(C)OC(=O)N1CC=CC[C@H]1c1nc2cc(Br)sc2c(=O)[nH]1>>CC(C)(C)OC(=O)N1CCCC[C@@H]1c1nc2cc(Br)sc2c(=O)[nH]1 -US20150158882A1,7,CC(C)(C)OC(=O)N1CC=CC[C@H]1c1nc2cc(Br)sc2c(=O)[nH]1>>CC(C)(C)OC(=O)N1CCCC[C@H]1c1nc2cc(Br)sc2c(=O)[nH]1 -US20140057953A1,3,COc1cccc(N(C)C(=O)c2ccc(Br)s2)c1.COc1ccccc1B(O)O>>COc1cccc(N(C)C(=O)c2ccc(-c3ccccc3OC)s2)c1 -US07662825B2,2,COc1ncc(C)nc1N.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>COc1ncc(C)nc1NS(=O)(=O)c1cccc(Cl)c1Cl -US08389766B2,2,Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(C#N)c(N)c1F.O=C(Cl)c1ccccc1>>Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(C#N)c(NC(=O)c2ccccc2)c1F -US20150252044A1,3,NC(=O)c1ccc2cncc(Br)c2n1.OB(O)c1ccccc1Cl>>NC(=O)c1ccc2cncc(-c3ccccc3Cl)c2n1 -US04431663,2,COc1cc(C)c([N+](=O)[O-])cc1C(=O)Cl.NCC1CCCO1>>COc1cc(C)c([N+](=O)[O-])cc1C(=O)NCC1CCCO1 -US07960407B2,9,CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCCl)cc1.[N-]=[N+]=[N-]>>CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCN=[N+]=[N-])cc1 -US06703421B1,1,CI.Cc1csc2ncnc(NC3Cc4ccccc4C3)c12>>Cc1csc2ncnc(N(C)C3Cc4ccccc4C3)c12 -US20120018672A1,6,CCCCOc1ccc(C2CCC3(CC2)OCCO3)c(F)c1F>>CCCCOc1ccc(C2CCC(=O)CC2)c(F)c1F -US08273773B2,6,COC(=O)c1cc(NS(C)(=O)=O)ccc1/C=C/c1cc(-c2cccnc2OCc2ccccc2)cc(C(C)(C)C)c1>>CC(C)(C)c1cc(/C=C/c2ccc(NS(C)(=O)=O)cc2C(=O)O)cc(-c2cccnc2OCc2ccccc2)c1 -US20140142085A1,6,CCOC(=O)C(CC)n1ccc(C(F)(F)F)n1>>CCC(C(=O)O)n1ccc(C(F)(F)F)n1 -US20120225857A1,3,CC1(C)OB(c2ccc3c(c2)CCCNC3=O)OC1(C)C.CCN(C)S(=O)(=O)c1ccc(-c2cnc(N)c(Br)n2)cc1>>CCN(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc4c(c3)CCCNC4=O)n2)cc1 -US06492420B2,2,CCCO.NCC(=O)CCC(=O)O>>CCCOC(=O)CCC(=O)CN -US20130324501A1,1,COC(=O)c1sccc1NS(C)(=O)=O.ClCCN1CCOCC1>>COC(=O)c1sccc1N(CCN1CCOCC1)S(C)(=O)=O -US08207168B2,1,CC(=O)Cc1ccc(O)cc1.CC(C)(C)OC(=O)N1CCC(O)CC1>>CC(=O)Cc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20030105328A1,1,CCOC(=O)c1cn(Cc2ccccc2C(F)(F)F)c2ccc(Oc3ccc(NC(C)=O)cc3)c(CCl)c2c1=O.CNCc1ccccc1>>CCOC(=O)c1cn(Cc2ccccc2C(F)(F)F)c2ccc(Oc3ccc(NC(C)=O)cc3)c(CN(C)Cc3ccccc3)c2c1=O -US06121271,2,Cc1sc2cc3ccccc3c(-c3ccc(O)c(C4CCCC4)c3)c2c1C.O=C(O)c1ccc(S(=O)(=O)Cl)cc1O>>Cc1sc2cc3ccccc3c(-c3ccc(OS(=O)(=O)c4ccc(C(=O)O)c(O)c4)c(C4CCCC4)c3)c2c1C -US08148383B2,1,CC1Cc2cc(B(O)O)ccc2O1.CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)[nH]c2nc(C)nn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc3c(c2)CC(C)O3)c2nc(C)nn12 -US20090137564A1,1,COc1c(F)cc(Cl)cc1C=O.Nc1cc(F)cc2[nH]c(=O)ccc12>>COc1c(F)cc(Cl)cc1C=Nc1cc(F)cc2[nH]c(=O)ccc12 -US20080096861A1,7,CC(C)CCN(Cc1nc2ccccc2n1CCC#N)C1CCCc2cccnc21>>CC(C)CCN(Cc1nc2ccccc2n1CCCN)C1CCCc2cccnc21 -US20090253689A1,7,N#Cc1cc2ncc(N)n2cc1-c1ccc(Cl)cc1Cl>>NCc1cc2ncc(N)n2cc1-c1ccc(Cl)cc1Cl -US07345180B2,1,CC(C)(C)OC(=O)CBr.O=C(OCc1ccccc1)c1ccc2[nH]ccc2c1>>CC(C)(C)OC(=O)Cn1ccc2cc(C(=O)OCc3ccccc3)ccc21 -US20110092553A1,2,CC(C)(C)c1ccc(Oc2ccc(-c3ccc(Cc4nc(-c5ccc(Cl)cc5Cl)cn4Cc4ccc(C(=O)O)cc4)cc3)cc2)cc1.CS(N)(=O)=O>>CC(C)(C)c1ccc(Oc2ccc(-c3ccc(Cc4nc(-c5ccc(Cl)cc5Cl)cn4Cc4ccc(C(=O)NS(C)(=O)=O)cc4)cc3)cc2)cc1 -US20050070605A1,2,CC(C)n1c(/C=C/[C@@H](O)C[C@@H](O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21>>CC(C)n1c(/C=C/[C@@H]2C[C@@H](O)CC(=O)O2)c(-c2ccc(F)cc2)c2ccccc21 -US20150111870A1,1,CC(C)c1c(Cl)nc2ccc(Br)cc2c1Cl.C[O-]>>COc1nc2ccc(Br)cc2c(Cl)c1C(C)C -US20140142083A1,2,CN(c1cc(Cl)nc(C(=O)O)c1Br)C1CCOCC1.Cc1cc(C)c(CN)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2nc(Cl)cc(N(C)C3CCOCC3)c2Br)c(=O)[nH]1 -US20100016282A1,2,COC(=O)[C@H](CCOCc1ccccc1)NCCN(CCC(=O)O)C(=O)OCc1ccccc1>>COC(=O)[C@H](CCOCc1ccccc1)N1CCN(C(=O)OCc2ccccc2)CCC1=O -US08470816B2,2,CN(C(=O)c1ccc(Br)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1.O=C(O)C1CCN(C(=O)CO)CC1>>CN(C(=O)c1ccc(Br)cc1)[C@@H]1CCN(C(=O)C2CCN(C(=O)CO)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US08470816B2,2,O=C(O)C1CCN(C(=O)CO)CC1>>O -US04405530,1,BrCc1ccccc1.OCCCCl>>ClCCCOCc1ccccc1 -US20120289702A1,1,Brc1cnc2ccccc2c1.Nc1cccc2c1C(=O)CC2>>O=C1CCc2cccc(Nc3cnc4ccccc4c3)c21 -US20090163471A1,6,CC(=O)Nc1cc(C(=O)OC(C)(C)C)ccc1C(N)=O>>CC(=O)Nc1cc(C(=O)O)ccc1C(N)=O -US20050143452A1,3,COc1ccc(B(O)O)cc1.Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1>>COc1ccc(-c2cccc3c2OC(COS(=O)(=O)c2ccc(C)cc2)C3)cc1 -US20080176857A1,1,CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(Cl)nc2s1.CNC(=O)CS>>CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(SCC(=O)NC)nc2s1 -US20100249123A1,7,CC(C)(C#N)c1ccc([N+](=O)[O-])cc1>>CC(C)(C#N)c1ccc(N)cc1 -US20100331315A1,1,CC(N)c1ccc(F)cc1.Clc1cncc(Cl)n1>>CC(Nc1cncc(Cl)n1)c1ccc(F)cc1 -US20100267697A1,6,CCN(CC)c1ccc(CN(C(=O)OC(C)(C)C)c2ccc(F)cc2)cn1>>CCN(CC)c1ccc(CNc2ccc(F)cc2)cn1 -US20060166985A1,6,CC(C)(C)OC(=O)NC(C(=O)N1CCOCC1)C1CCOCC1>>NC(C(=O)N1CCOCC1)C1CCOCC1 -US04804668,2,CN.COC(=O)c1nc(C)c(-c2ccncc2)s1>>CNC(=O)c1nc(C)c(-c2ccncc2)s1 -US07432293B2,9,COC(=O)c1cccc(C=O)c1.NO>>COC(=O)c1cccc(C=NO)c1 -US06372740B1,6,CCN(C(=O)Cn1c(=O)n(C)c2nc(-c3ccccc3)ncc21)c1ccc(OC)cc1>>CCN(C(=O)Cn1c(=O)n(C)c2nc(-c3ccccc3)ncc21)c1ccc(O)cc1 -US08361962B2,6,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1C>>C[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1C(=O)O -US08772480B2,9,Cc1nc(Cl)c(N)c(Cl)n1.[NH4+]>>Cc1nc(N)c(N)c(Cl)n1 -US07098212B2,1,C[C@H]1CN(C(=O)COc2ccc(Cl)cc2O)[C@H](C)CN1Cc1ccc(F)cc1.N#CCBr>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2OCC#N)[C@H](C)CN1Cc1ccc(F)cc1 -US20150038437A1,1,C1CCNC1.CCc1c(-c2ccc3c(c2)c(C#N)c(Cl)n3C)nc(OCc2ccccc2)c(C(=O)OC)c1OCc1ccccc1>>CCc1c(-c2ccc3c(c2)c(C#N)c(N2CCCC2)n3C)nc(OCc2ccccc2)c(C(=O)OC)c1OCc1ccccc1 -US06964961B2,1,CO[C@H]1CCN(C(=O)c2cc3nccc(Cl)c3s2)C1.Cc1[nH]c2ccc(N)cc2c1C>>CO[C@H]1CCN(C(=O)c2cc3nccc(Nc4ccc5[nH]c(C)c(C)c5c4)c3s2)C1 -US08633200B2,7,COC(=O)C(=O)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1-c1ccc(F)cc1>>COC(=O)[C@@H](O)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1-c1ccc(F)cc1 -US05318966,2,CC1(C)CC(=O)N(CCCCCCN2CC[C@@H]3c4cccc(O)c4CC[C@@H]32)C(=O)C1.CN(C)C(=O)Cl>>CN(C)C(=O)Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCCCCCN1C(=O)CC(C)(C)CC1=O -US05783575,6,COC(=O)c1cc2c3cc(Cl)ccc3n(C)c2s1>>Cn1c2ccc(Cl)cc2c2cc(C(=O)O)sc21 -US20080027049A1,2,CCCCC(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCCC3>>CCCCC(=O)Nc1ccc2oc3c(c2c1)CCCCCC3 -US20140154179A1,2,Cc1ccn2ccnc(N3CC[C@H](N)C3)c12.O=C(O)c1ccn(-c2ccc(Cl)cc2)n1>>Cc1ccn2ccnc(N3CC[C@H](NC(=O)c4ccn(-c5ccc(Cl)cc5)n4)C3)c12 -US20140171403A1,1,CN(CCC=O)C(=O)OC(C)(C)C.O=C(OCc1cc(Cl)cc(Cl)c1)N1CCNCC1>>CN(CCCN1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)C(=O)OC(C)(C)C -US06884774B2,9,CC(C)(C)OC(=O)N1CCC(c2ccc(C(N)=O)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(C#N)cc2)CC1 -US20150246882A1,6,CCOC(=O)[C@@H]1Cc2ccccc2N1C(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1>>CCOC(=O)[C@@H]1Cc2ccccc2N1C(=O)[C@@H](N)c1ccccc1 -US20030064248A1,3,Brc1ccc2c(c1)Cc1ccccc1-2.CC(=O)OC(C)=O>>CC(=O)c1ccc2c(c1)Cc1cc(Br)ccc1-2 -US20130040933A1,2,C[C@H](Nc1cncc(-c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)n1)C(=O)O.NCC(F)(F)F>>C[C@H](Nc1cncc(-c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)n1)C(=O)NCC(F)(F)F -US20110144110A1,7,Cc1cc(-c2ncc[nH]2)ccc1[N+](=O)[O-]>>Cc1cc(-c2ncc[nH]2)ccc1N -US20080269193A1,1,CC1(C)CC(=O)c2c(C(F)(F)F)n[nH]c2C1.N#Cc1c(F)cc(Br)cc1N[C@H]1CCC[C@@H]1O>>CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3cc(F)c(C#N)c(N[C@H]4CCC[C@@H]4O)c3)c2C1 -US05068325,1,N#Cc1ccc(C=CCBr)cc1.Nc1nc2c(s1)CCNCC2>>N#Cc1ccc(/C=C/CN2CCc3nc(N)sc3CC2)cc1 -US06432950B1,1,Cc1cc2c(Cl)nc(-c3cnccn3)nc2s1.NCc1ccccc1>>Cc1cc2c(NCc3ccccc3)nc(-c3cnccn3)nc2s1 -US20080039625A1,7,O=[N+]([O-])c1c(C=C(Br)Br)ccc2ccccc12>>Nc1c(C=C(Br)Br)ccc2ccccc12 -US05693635,2,CCOC(=O)c1ccc(N)cc1.Cc1ccccc1C(=O)Cl>>CCOC(=O)c1ccc(NC(=O)c2ccccc2C)cc1 -US07803938B2,1,C1=COCCC1.CC(C)[Si](OCc1ccc(C(O)c2cccc(C#N)c2)cc1)(C(C)C)C(C)C>>CC(C)[Si](OCc1ccc(C(OC2CCCCO2)c2cccc(C#N)c2)cc1)(C(C)C)C(C)C -US08551999B2,2,Nc1ccc(Oc2ccc3c(c2)CCN3CC(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)nc1.O=C(Cl)c1ccc(Cl)c(Cl)c1>>O=C(Nc1ccc(Oc2ccc3c(c2)CCN3CC(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)nc1)c1ccc(Cl)c(Cl)c1 -US04144349,4,COc1ccc(NN)cc1.O=C1CCCSCCC1>>COc1ccc2[nH]c3c(c2c1)CCSCCC3 -US20130040930A1,6,Cc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)c(C)n1>>Cc1ccc(N2CCNCC2)c(C)n1 -US06630600B1,6,CCOC(=O)C(Cc1ccc(OCCc2ccc(OCc3ccccc3)cc2)cc1)OCC>>CCOC(=O)C(Cc1ccc(OCCc2ccc(O)cc2)cc1)OCC -US07332497B2,1,Nc1ccc(Br)cc1.O=S1(=O)N=C(Cl)c2ccccc21>>O=S1(=O)N=C(Nc2ccc(Br)cc2)c2ccccc21 -US20110275673A1,2,CCCCCCCc1nc(-c2ccc(CN)cc2)no1.O=C(N[C@@H](CCOC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21>>CCCCCCCc1nc(-c2ccc(CNC(=O)[C@H](CCOC(c3ccccc3)(c3ccccc3)c3ccccc3)NC(=O)OCC3c4ccccc4-c4ccccc43)cc2)no1 -US05055458,6,CCOP(=O)(COCCC(CO[Si](C)(C)C(C)(C)C)On1cnc2c(N)ncnc21)OCC>>CCOP(=O)(COCCC(CO)On1cnc2c(N)ncnc21)OCC -US20050096298A1,1,CC(C)n1cnc2c(Cl)nc(F)nc21.Nc1cccc(Cl)c1>>CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(F)nc21 -US20120088750A1,9,CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(Br)c2s1.[C-]#N>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(C#N)c2s1 -US20050288304A1,1,Brc1cccc(N2CCOCC2)n1.CN1CCN(C2CCCc3ccc(C4CCCNC4)cc32)CC1>>CN1CCN(C2CCCc3ccc(C4CCCN(c5cccc(N6CCOCC6)n5)C4)cc32)CC1 -US20060084640A1,6,COC(=O)c1nc(N2CCN(c3ncccc3C(F)(F)F)CC2)n(COCC[Si](C)(C)C)c1-c1ccc(C(F)(F)F)cc1>>C[Si](C)(C)CCOCn1c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc(C(=O)O)c1-c1ccc(C(F)(F)F)cc1 -US05830920,6,CC(=O)OC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=O)NC[C@H]1O[C@@](O)(Cc2ccccc2)[C@H](NC(=O)OCc2ccccc2)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=O)NC[C@H]1O[C@@](O)(Cc2ccccc2)[C@H](N)[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US20110105514A1,8,OCCCc1ccc(F)c(C(F)(F)F)c1>>O=CCCc1ccc(F)c(C(F)(F)F)c1 -US20080004321A1,6,CCCc1c(OCc2cccc(C(=O)Nc3cccc(C(=O)OC)c3)n2)ccc(C(C)=O)c1O>>CCCc1c(OCc2cccc(C(=O)Nc3cccc(C(=O)O)c3)n2)ccc(C(C)=O)c1O -US07232820B2,2,CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)O.CCCCC(CC)c1nnc(N)s1>>CCCCC(CC)c1nnc(NC(=O)[C@H](CCC)NC2CCc3cc(F)cc(F)c3C2)s1 -US20130172302A1,1,O=C(CBr)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(c1ccc(Cl)cc1)N1CCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(c1ccc(Cl)cc1)N1CCCCC1)C2)c1ccccc1 -US20060235021A1,3,C[Sn](C)(C)c1c(F)cncc1F.N#Cc1cccnc1-c1cc(-c2cnnc(Cl)c2)ccc1F>>N#Cc1cccnc1-c1cc(-c2cnnc(-c3c(F)cncc3F)c2)ccc1F -US06239131B1,1,COCCl.COc1ccc2c(c1)NC(=O)CCN2c1ccccc1>>COCN1C(=O)CCN(c2ccccc2)c2ccc(OC)cc21 -US20090029958A1,7,O=C(O)COCCc1ccccc1>>OCCOCCc1ccccc1 -US20070254869A1,9,CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)Cl)c2cc(Cl)ccc21.NN>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)NN)c2cc(Cl)ccc21 -US20150197509A1,2,CC(C)N(CC(=O)O)S(=O)(=O)c1ccc(F)cc1.NCc1cc(N2CCC(C(F)(F)F)CC2)ncn1>>CC(C)N(CC(=O)NCc1cc(N2CCC(C(F)(F)F)CC2)ncn1)S(=O)(=O)c1ccc(F)cc1 -US08101649B2,2,CCO.O=C(O)CCc1c[nH]c2ccccc12>>CCOC(=O)CCc1c[nH]c2ccccc12 -US20100056524A1,7,O=[N+]([O-])c1ccc(NCC2CCOCC2)nc1>>Nc1ccc(NCC2CCOCC2)nc1 -US04024271,1,ClCc1nsc(Cl)n1.NCCS>>NCCSCc1nsc(Cl)n1 -US08222251B2,2,C[C@@H]1CNCCN1c1nnc(-c2ccccc2)c2ccncc12.O=C(Cl)N1CCCCC1>>C[C@@H]1CN(C(=O)N2CCCCC2)CCN1c1nnc(-c2ccccc2)c2ccncc12 -US08962627B2,7,CC(C)(C)ON=c1cc(-c2cc3ccccc3cn2)oc2cc(C#Cc3ccccc3)ccc12>>CC(C)(C)ON=c1cc(-c2cc3ccccc3cn2)oc2cc(CCc3ccccc3)ccc12 -US04925867,8,CC1CN(OCc2ccccc2)C(=O)C1O>>CC1CN(OCc2ccccc2)C(=O)C1=O -US04143146,9,ClC(Cl)(Cl)Cl.O=C(CCC(=O)OCc1ccccc1)NCO>>O=C(CCC(=O)OCc1ccccc1)NCCl -US20050143422A1,2,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.Cc1c(C(=O)O)oc2ccccc12>>Cc1c(C(=O)Nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)oc2ccccc12 -US20150175628A1,2,COC(=O)c1ccc(C(=O)OC)cc1.NN>>COC(=O)c1ccc(C(=O)NN)cc1 -US20090093491A1,1,C#CCCBr.c1c[nH]cn1>>C#CCCn1ccnc1 -US08269008B2,9,CCC(=O)c1ccccc1.NO>>CCC(=NO)c1ccccc1 -US20150045378A1,6,COC(=O)CC(c1ccc(F)c(OC)c1)C1CC1>>COC(=O)CC(c1ccc(F)c(O)c1)C1CC1 -US20060040957A1,1,ClCc1ccc(Cl)cc1.O=c1cc2sccn2c(=O)[nH]1>>O=c1cc2sccn2c(=O)n1Cc1ccc(Cl)cc1 -US20150072969A1,6,CCOC(=O)CC1(c2ccc(OCc3cccc(-c4c(C)cc(OCC5CCCO5)cc4C)c3)cc2)COC1>>Cc1cc(OCC2CCCO2)cc(C)c1-c1cccc(COc2ccc(C3(CC(=O)O)COC3)cc2)c1 -US20130267493A1,3,COC(C)c1ccc(B(O)O)cc1.O=C(O)c1n[nH]c2cc(Cl)c(Br)cc12>>COC(C)c1ccc(-c2cc3c(C(=O)O)n[nH]c3cc2Cl)cc1 -US07186731B2,9,COC(=O)[C@@H]1[C@@H]2C[C@@H](OC(C)=O)[C@@H]([C@H]2I)N1[C@H](C)c1ccccc1>>COC(=O)[C@@H]1[C@H]2C[C@H]([C@H](OC(C)=O)C2)N1[C@H](C)c1ccccc1 -US05635510,2,COc1ccc(C(=O)Cl)cc1.OCCC1(c2ccc(Cl)c(Cl)c2)CCNC1>>COc1ccc(C(=O)N2CCC(CCO)(c3ccc(Cl)c(Cl)c3)C2)cc1 -US20020119969A1,2,CC(C)NC(=N)N.O=S(=O)(Cl)c1sc(Cl)cc1Br>>CC(C)NC(=N)NS(=O)(=O)c1sc(Cl)cc1Br -US20070232594A1,1,CC(C)(C)c1c(F)ccc(C(=O)O)c1C(F)(F)F.OCCOCc1ccccc1>>CC(C)(C)c1c(OCCOCc2ccccc2)ccc(C(=O)O)c1C(F)(F)F -US06107307,7,CN1C2C=C(c3cncc4ccccc34)CC1CC2>>CN1C2CCC1CC(c1cncc3ccccc13)C2 -US04618627,3,CCCCCCC(=O)CCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1.CI>>CCCCCCC(C)(O)CCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1 -US07214674B2,1,Cc1ccc2c(OCCBr)cc(Cl)cc2n1.O=C1COc2c(CC3CCNCC3)cccc2N1>>Cc1ccc2c(OCCN3CCC(Cc4cccc5c4OCC(=O)N5)CC3)cc(Cl)cc2n1 -US04746661,1,BrCCCBr.O=C1CCc2cc(O)ccc2N1>>O=C1CCc2cc(OCCCBr)ccc2N1 -US20040138230A1,1,CC1CC(=O)Nc2ccccc21.CI>>CC1CC(=O)N(C)c2ccccc21 -US20110130393A1,1,N#Cc1cn(-c2ccccc2)nc1N.O=S1(=O)CCN(Cc2ccc(I)cc2)CC1>>N#Cc1cn(-c2ccccc2)nc1Nc1ccc(CN2CCS(=O)(=O)CC2)cc1 -US20100292210A1,6,Cn1cc(-c2ccc(Nc3ccc4c(n3)O[C@H](c3ccccc3)CN(C(=O)OC(C)(C)C)C4)nc2)cn1>>Cn1cc(-c2ccc(Nc3ccc4c(n3)O[C@H](c3ccccc3)CNC4)nc2)cn1 -US20050182103A1,6,COC(=O)c1cnc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1>>O=C(O)c1cnc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1 -US20110201604A1,7,CNC(=O)c1ccc([N+](=O)[O-])c(NC)c1>>CNC(=O)c1ccc(N)c(NC)c1 -US20150045378A1,2,CO.O=C(O)/C=C/c1cccc(O)c1>>COC(=O)/C=C/c1cccc(O)c1 -US07897618B2,2,Cc1nc(C(=O)O)c(-c2ccc(F)cc2)s1.c1ccc2sc(CC3CCCCN3)nc2c1>>Cc1nc(C(=O)N2CCCCC2Cc2nc3ccccc3s2)c(-c2ccc(F)cc2)s1 -US07507841B2,6,Cc1c(C)c2c(c(C)c1NCc1ccccc1)C(=O)C(C)(C)O2>>Cc1c(C)c2c(c(C)c1N)C(=O)C(C)(C)O2 -US07816534B2,6,COC(=O)CC(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>O=C(O)CC(c1ccc(Cl)cc1)c1ccc(Cl)cc1 -US20120142659A1,2,CC[C@@H](CN1CC(O)C1)NC.O=C(O)c1ccc(Br)cc1>>CC[C@@H](CN1CC(O)C1)N(C)C(=O)c1ccc(Br)cc1 -US06627651B1,6,COC(=O)C1=Cc2cc(OCc3ccccc3OC)ccc2S(=O)(=O)CC1>>COc1ccccc1COc1ccc2c(c1)C=C(C(=O)O)CCS2(=O)=O -US04101522,2,CC(C)(C)N=NC(C)(C#N)CCCO.O=C(Cl)c1ccc2c(c1)C(=O)OC2=O>>CC(C)(C)N=NC(C)(C#N)CCCOC(=O)c1ccc2c(c1)C(=O)OC2=O -US20140371212A1,6,COC(=O)c1cnc(OC2CC2)cn1>>O=C(O)c1cnc(OC2CC2)cn1 -US20100055071A1,3,CC1(C)OB(c2ccc(C(=O)NC3CC3)cc2)OC1(C)C.O=C(OCc1ccccc1)N1CCC[C@H]1c1nc2ncc(Br)cc2[nH]1>>O=C(NC1CC1)c1ccc(-c2cnc3nc([C@@H]4CCCN4C(=O)OCc4ccccc4)[nH]c3c2)cc1 -US05017608,2,CC(=O)OC(C)=O.Clc1cc2c(cc1Cl)C1=C(CC2)NCCC1>>CC(=O)N1CCCC2=C1CCc1cc(Cl)c(Cl)cc12 -US06180316B2,3,C1=CCC=C1.COC(=O)C1(C)CC2C=CC1C2>>COC(=O)C1(C)CC2CC1C1C3C=CC(C3)C21 -US20130178478A1,6,CCCc1cc(C)cc(Nc2cc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)nnc2C(N)=O)n1>>CCCc1cc(C)cc(Nc2cc(N[C@@H]3CCCC[C@@H]3N)nnc2C(N)=O)n1 -US20110311458A1,1,COC(=O)C(Br)c1cccc(F)c1.Nc1cc(F)c(F)c(F)c1>>COC(=O)C(Nc1cc(F)c(F)c(F)c1)c1cccc(F)c1 -US20110190227A1,1,CCOC(=O)Cc1cccc(Oc2ccc(Br)cc2CBr)c1.Sc1ccc2ccccc2n1>>CCOC(=O)Cc1cccc(Oc2ccc(Br)cc2CSc2ccc3ccccc3n2)c1 -US08288419B2,2,CC(F)(F)CCCCn1ccc(N)n1.O=C(O)/C=C/c1ccc(C(F)(F)F)cc1>>CC(F)(F)CCCCn1ccc(NC(=O)/C=C/c2ccc(C(F)(F)F)cc2)n1 -US05770615,1,CN(C)CCO.Nc1cccc(O)c1>>CN(C)CCOc1cccc(N)c1 -US20050203087A1,1,CC(C)(C)C(=O)OCI.COC(=O)COc1c(C(=O)O)sc(-c2cccc(C3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br>>COC(=O)COc1c(C(=O)OCOC(=O)C(C)(C)C)sc(-c2cccc(C3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br -US07220744B2,2,CS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)O)c1.FC(F)(F)c1csc(N2CCNCC2)n1>>CS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)N2CCN(c3nc(C(F)(F)F)cs3)CC2)c1 -US06410592B1,1,CNC[C@H]1CCc2cc(OC)ccc2[C@H]1c1ccccc1.COC(=O)C(C)Br>>COC(=O)C(C)N(C)C[C@H]1CCc2cc(OC)ccc2[C@H]1c1ccccc1 -US06825199B2,1,CC(C)(C)OC(=O)NC1CCNC1.O=c1c2cc(F)c(F)cc2n(-c2cccc(F)c2)c(=O)n1OCc1ccccc1>>CC(C)(C)OC(=O)NC1CCN(c2cc3c(cc2F)c(=O)n(OCc2ccccc2)c(=O)n3-c2cccc(F)c2)C1 -US20100216766A1,2,Cn1cnc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)c1.O=C(Cc1ccccc1F)N=C=S>>Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5F)cc4F)c3s2)c1 -US09018214B2,6,C[C@@H]1CN(CC(=O)OCc2ccccc2)[C@@H](CN2CCOC2=O)CN1C(=O)OC(C)(C)C>>C[C@@H]1CN(CC(=O)O)[C@@H](CN2CCOC2=O)CN1C(=O)OC(C)(C)C -US20120225854A1,1,CC#CC1CN(S(=O)(=O)c2ccc(Cl)nc2)CCN1.OC(c1cnc(Cl)nc1)(C(F)(F)F)C(F)(F)F>>CC#CC1CN(S(=O)(=O)c2ccc(Cl)nc2)CCN1c1ncc(C(O)(C(F)(F)F)C(F)(F)F)cn1 -US05420298,1,COC1(c2cccc(OCc3ccc4ccccc4c3)c2)CCNC1.N#CCCl>>COC1(c2cccc(OCc3ccc4ccccc4c3)c2)CCN(CC#N)C1 -US20090270414A1,4,N#CC1CCC(=O)CC1.NNc1ccccc1>>N#CC1CCc2[nH]c3ccccc3c2C1 -US08168658B2,2,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1N.CCOC(=O)C(NC(=O)OC(C)(C)C)c1ccc(C(=O)O)cc1>>CCOC(=O)C(NC(=O)OC(C)(C)C)c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2NC(=O)OC(C)(C)C)cc1 -US08557807B2,1,C1COCCN1.O=c1cc(N2CCOCC2)oc2c(-c3ccc(Cl)cc3)csc12>>O=c1cc(N2CCOCC2)oc2c(-c3ccc(N4CCOCC4)cc3)csc12 -US08426420B2,6,CCCOC(=O)N1CCN(C(=O)C(NC(=O)OCc2ccccc2)C(C)F)CC1>>CCCOC(=O)N1CCN(C(=O)C(N)C(C)F)CC1 -US20130158075A1,6,COC(=O)C12CC3CC(C1)CC(c1ncc(-c4ccc(NC(=O)Nc5cccc(C(F)(F)F)c5)cc4)s1)(C3)C2>>O=C(Nc1ccc(-c2cnc(C34CC5CC(CC(C(=O)O)(C5)C3)C4)s2)cc1)Nc1cccc(C(F)(F)F)c1 -US20100331309A1,1,Cc1cc(C)c2c(c1)[C@@H](Nc1nnn(C)n1)CCCN2C(=O)OCc1ccccc1.FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1>>Cc1cc(C)c2c(c1)[C@@H](N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1)CCCN2C(=O)OCc1ccccc1 -US20120202851A1,7,CC1(C)CC(=O)C=C(c2ccncc2[N+](=O)[O-])C1>>CC1(C)CC(c2ccncc2[N+](=O)[O-])=CC(O)C1 -US20100087424A1,1,NC1CCN(C[C@H]2COc3c(F)cnc4ccc(=O)n2c34)CC1.O=Cc1cc2c(cn1)OCS2>>O=c1ccc2ncc(F)c3c2n1[C@@H](CN1CCC(NCc2cc4c(cn2)OCS4)CC1)CO3 -US20130102617A1,6,CC1(C)COC2(CC[C@H](C[C@@H](C(=O)O)c3ccc(S(=O)(=O)C4CC4)c(C4CC4)c3)C2)OC1>>O=C1CC[C@H](C[C@@H](C(=O)O)c2ccc(S(=O)(=O)C3CC3)c(C3CC3)c2)C1 -US05684011,1,BrCCC1OCCO1.Sc1ncccn1>>c1cnc(SCCC2OCCO2)nc1 -US20060276464A1,2,CCCc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)Cl.NCCc1ccncc1>>CCCc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)NCCc1ccncc1 -US20150038438A1,8,COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)CCCc2cc4c(cc2-3)cc(CO)n4C)c(OC)c1>>COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)CCCc2cc4c(cc2-3)cc(C=O)n4C)c(OC)c1 -US20080176884A1,1,BrCc1ccccc1.Oc1ccc2c3c1O[C@H]1CCC[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314>>O[C@@]12CCC[C@@H]3Oc4c(OCc5ccccc5)ccc5c4[C@@]31CCN(CC1CC1)[C@@H]2C5 -US07507740B2,1,Nc1ccc(OCc2cccc(F)c2)c(Cl)c1.OCc1ccc(Cn2ccc3ncnc(Cl)c32)cc1>>OCc1ccc(Cn2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c32)cc1 -US20110144068A1,2,COc1ccc(Cn2cc(-c3ccnc(NC(C)(C)C)c3)c(-c3cccc(N)c3)n2)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>COc1ccc(Cn2cc(-c3ccnc(NC(C)(C)C)c3)c(-c3cccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c3)n2)cc1 -US20060079696A1,1,C1CCNCC1.N#Cc1cccc(F)c1F>>N#Cc1cccc(F)c1N1CCCCC1 -US05962457,7,O=c1c2sccc2nc(C=Cc2ccccn2)n1-c1ccccc1Cl>>O=c1c2sccc2nc(CCc2ccccn2)n1-c1ccccc1Cl -US04888355,2,CN[C@@H]1c2ccccc2C[C@H]1N1CCCC1.O=C(O)Cc1ccc(-c2ccccc2)s1>>CN(C(=O)Cc1ccc(-c2ccccc2)s1)[C@@H]1c2ccccc2C[C@H]1N1CCCC1 -US20070129347A1,7,CN(C)C1(c2ccccc2)CCC(=CC(=O)NCCCc2c[nH]c3ccccc23)CC1>>CN(C)C1(c2ccccc2)CCC(CC(=O)NCCCc2c[nH]c3ccccc23)CC1 -US06787541B1,2,CC(C)CC(=O)Cl.NCCNc1nc(C(=O)c2cccs2)c2sccc2n1>>CC(C)CC(=O)NCCNc1nc(C(=O)c2cccs2)c2sccc2n1 -US04719223,5,N#Cc1cc(Cl)c(N)c(Cl)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>N#Cc1cc(Cl)c(NC(=O)C(F)(F)F)c(Cl)c1 -US07264792B2,9,COC(=O)C1(NC(=O)OC(C)(C)C)CC(OS(=O)(=O)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)CC(I)CCCCCCCCC(=O)O)C1>>COC(=O)C1(NC(=O)OC(C)(C)C)CC(OS(=O)(=O)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)CCCCCCCCCCC(=O)O)C1 -US20080076806A1,2,NC(c1ccccc1)c1cccc(C(F)(F)F)c1.O=C(O)CNC(=O)CCc1ccccc1>>O=C(CCc1ccccc1)NCC(=O)NC(c1ccccc1)c1cccc(C(F)(F)F)c1 -US05013852,2,O=C(O)c1c(-c2ccccc2)oc2ccccc2c1=O.c1ccc(CN2CCNCC2)cc1>>O=C(c1c(-c2ccccc2)oc2ccccc2c1=O)N1CCN(Cc2ccccc2)CC1 -US20070260058A1,1,CC(=O)c1ccc(F)cc1.CCc1c[nH]cn1>>CCc1cn(-c2ccc(C(C)=O)cc2)cn1 -US05217958,2,COC(=O)[C@@H](N)Cc1ccccc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)Oc1ccc([N+](=O)[O-])cc1 -US06969725B2,9,CCO[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](O)c1ccc(OCc2ccccc2)cc1C>>CCO[C@@H](Cc1ccc(OCc2ccccc2)cc1C)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1 -US08399465B2,3,C1COCCN1.C=O.CC(=O)Oc1ccc2cc[nH]c2c1>>CC(=O)Oc1ccc2c(CN3CCOCC3)c[nH]c2c1 -US07919502B2,2,NCc1ccc(Cl)cc1.O=C(O)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1>>O=C(NCc1ccc(Cl)cc1)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1 -US04220658,9,N#CN.Nc1c(Cl)cccc1Cl>>N=C(N)Nc1c(Cl)cccc1Cl -US20130184282A1,7,Cc1ccc(-c2nc3c(C=O)cn(CCCCCCC(=O)O)c3nc2-c2ccc(C)cc2)cc1>>Cc1ccc(-c2nc3c(CO)cn(CCCCCCC(=O)O)c3nc2-c2ccc(C)cc2)cc1 -US20080051418A1,7,CCOC(=O)/C=C/c1ccc(OCC)nc1Oc1ccc(Cl)cc1Cl>>CCOC(=O)CCc1ccc(OCC)nc1Oc1ccc(Cl)cc1Cl -US20120015991A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)O[C@H](C)c1ccccc1C#N>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC(=O)O[C@H](C)c4ccccc4C#N)cc3)cc2)CC1 -US20090105217A1,6,CCc1cc(NC(=O)c2ccccc2F)ccc1C(=O)NNC(=O)OC(C)(C)C>>CCc1cc(NC(=O)c2ccccc2F)ccc1C(=O)NN -US05354747,2,C1CCN(C2CCNCC2)CC1.O=C(Cl)N1Cc2ccccc2Oc2ccc(Cl)cc21>>O=C(N1CCC(N2CCCCC2)CC1)N1Cc2ccccc2Oc2ccc(Cl)cc21 -US20050124692A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1Cc2ccc3c(c2O1)CCCC3>>Cc1ccc(S(=O)(=O)OCC2Cc3ccc4c(c3O2)CCCC4)cc1 -US20130172339A1,2,Nc1cccc(C(=O)O)c1.O=S(=O)(Cl)c1cccc(-c2ccccc2)c1>>O=C(O)c1cccc(NS(=O)(=O)c2cccc(-c3ccccc3)c2)c1 -US20080242663A1,1,CI.Cc1cccc(CO)c1Nc1ccnc(Cl)n1>>Cc1cccc(CO)c1N(C)c1ccnc(Cl)n1 -US20040018192A1,1,O=S(=O)(Nc1cccc2c(Cl)c[nH]c12)c1ccc(CCCBr)cc1.c1c[nH]cn1>>O=S(=O)(Nc1cccc2c(Cl)c[nH]c12)c1ccc(CCCn2ccnc2)cc1 -US05783572,1,COc1nc2cc(Cl)c(Cl)c(C(C)Cl)c2nc1OC.c1c[nH]cn1>>COc1nc2cc(Cl)c(Cl)c(C(C)n3ccnc3)c2nc1OC -US08481555B2,8,O=C(OO)c1cccc(Cl)c1.c1ccc(-c2cnc(NC3=NC[C@@]4(CN5CCC4CC5)O3)s2)cc1>>[O-][N+]12CCC(CC1)[C@]1(CN=C(Nc3ncc(-c4ccccc4)s3)O1)C2 -US20040132716A1,2,CN1CCC(C2CCNCC2)CC1.O=C(O)C(CC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)Cc1ccc2c(c1)CCCC2>>CN1CCC(C2CCN(C(=O)C(CC(=O)N3CCC(N4Cc5ccccc5NC4=O)CC3)Cc3ccc4c(c3)CCCC4)CC2)CC1 -US07754759B2,3,C[Si](C)(C)C[Mg+].O=CCCc1ccc(S(=O)(=O)c2ccccc2)cc1Br>>C[Si](C)(C)CC(O)CCc1ccc(S(=O)(=O)c2ccccc2)cc1Br -US20040058907A1,6,CC(C)(C)OC(=O)N1CCC(NC(=O)NCC2CN(Cc3ccc(Cl)c(Cl)c3)CCO2)CC1>>O=C(NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1)NC1CCNCC1 -US05686482,1,COc1cc(Cl)c([N+](=O)[O-])cc1C(=O)O.C[S-]>>COc1cc(SC)c([N+](=O)[O-])cc1C(=O)O -US05112998,6,COCO[C@@H]1CC2=CC=C3[C@@H]4CC[C@H](C(C)C5OCCO5)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@@H](OC(C)=O)C1>>COCO[C@@H]1CC2=CC=C3[C@@H]4CC[C@H](C(C)C=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@@H](OC(C)=O)C1 -US20140051679A1,3,CC(C)(C)OC(=O)Nc1ccc2[nH]nc(I)c2c1.CC1(C)OB(c2ccc(N3CCC(O)CC3)cc2)OC1(C)C>>CC(C)(C)OC(=O)Nc1ccc2[nH]nc(-c3ccc(N4CCC(O)CC4)cc3)c2c1 -US20110212968A1,6,COC(=O)c1nc(C)oc1-c1ccc(C)c(C)c1>>Cc1nc(C(=O)O)c(-c2ccc(C)c(C)c2)o1 -US20100063077A1,1,COc1cccc(N)c1.Clc1ccc(Nc2ncc(Br)cn2)cc1Cl>>COc1cccc(Nc2cnc(Nc3ccc(Cl)c(Cl)c3)nc2)c1 -US20100056527A1,1,CCOC(=O)c1cc(C)[nH]n1.CS(=O)(=O)OCc1cc(Cl)cc2cc(-c3cccnc3)oc12>>CCOC(=O)c1cc(C)n(Cc2cc(Cl)cc3cc(-c4cccnc4)oc23)n1 -US08507528B2,2,CS(=O)(=O)Cl.OCCc1ccc(F)cc1F>>CS(=O)(=O)OCCc1ccc(F)cc1F -US05217961,1,Cc1ccc(N)cc1.O=C(CCl)Nc1ccccc1C(=O)O>>Cc1ccc(NCC(=O)Nc2ccccc2C(=O)O)cc1 -US06511974B1,1,Cc1cc[nH]n1.O=C(c1ccc(Cl)nc1Cl)N1Cc2cccn2Cc2ccccc21>>Cc1ccn(-c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)c(Cl)n2)n1 -US20080045521A1,6,CCC(COc1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)OC)cc1)c1cccc(N(C)C(=O)OC(C)(C)C)n1>>CCC(COc1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)OC)cc1)c1cccc(NC)n1 -US20070129334A1,7,Cc1cccc([N+](=O)[O-])c1Br>>Cc1cccc(N)c1Br -US20110245257A1,1,CNC(=O)c1cccc([N+](=O)[O-])c1Br.Nc1cncc(F)c1>>CNC(=O)c1cccc([N+](=O)[O-])c1Nc1cncc(F)c1 -US20080064880A1,6,CCCC1(CCC)c2cc(-c3nc4cc(C)ccc4o3)ccc2-c2cc(OC)c(-c3nc4cc(C)ccc4o3)cc21>>CCCC1(CCC)c2cc(-c3nc4cc(C)ccc4o3)ccc2-c2cc(O)c(-c3nc4cc(C)ccc4o3)cc21 -US04725600,1,C1=CCNCC1.COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c(Cl)n2)cc1OC>>COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c(N3CC=CCC3)n2)cc1OC -US08637525B2,1,Fc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1.NCCCO>>OCCCNc1nc(Cl)nc2c1CCC2c1ccc(F)cc1 -US05912246,1,ClCc1cn2cc(Cl)ccc2n1.c1ccc(N2CCNCC2)cc1>>Clc1ccc2nc(CN3CCN(c4ccccc4)CC3)cn2c1 -US20040122244A1,2,COC1=C(OC)C(=O)C(Cc2ccc(OCc3cccnc3)c(C(=O)O)c2)=C(C)C1=O.COc1cc(N)cc(OC)c1OC>>COC1=C(OC)C(=O)C(Cc2ccc(OCc3cccnc3)c(C(=O)Nc3cc(OC)c(OC)c(OC)c3)c2)=C(C)C1=O -US08148383B2,6,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](C(=O)OCC)CC2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](C(=O)O)CC2)c2ncnn12 -US20080076806A1,2,CC(=O)c1ccc(C(=O)O)cc1.NCC(=O)NC(c1ccccc1)c1ccc(Cl)cc1>>CC(=O)c1ccc(C(=O)NCC(=O)NC(c2ccccc2)c2ccc(Cl)cc2)cc1 -US04655824,1,COC(=O)c1cc(Cl)cc(Cl)n1.Oc1ccc(C(F)(F)F)cc1Cl>>COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)cc(Cl)n1 -US08476253B2,7,CN(CCCN(C)C(=O)Cc1ccc([N+](=O)[O-])cc1)C(=O)CO[C@H]1Cc2ccccc2C12CCN(CC[C@@]1(c3ccc(F)cc3)CN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CO1)CC2>>CN(CCCN(C)C(=O)Cc1ccc(N)cc1)C(=O)CO[C@H]1Cc2ccccc2C12CCN(CC[C@@]1(c3ccc(F)cc3)CN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CO1)CC2 -US20100034827A1,8,Cc1cc(C(C)(C)O[SiH2]C(C)(C)C)ccn1.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C(C)(C)O[SiH2]C(C)(C)C)cc[n+]1[O-] -US04695581,3,CCC(=O)Cl.COc1c(C)cccc1C>>CCC(=O)c1cc(C)c(OC)c(C)c1 -US20120202815A1,1,CNC(=O)NCc1cc(Br)ccc1Cl.c1cc(-c2ccc3c(c2)CCCO3)n[nH]1>>CNC(=O)NCc1cc(-n2ccc(-c3ccc4c(c3)CCCO4)n2)ccc1Cl -US20020119961A1,1,CCOC(=O)C1CCC(=O)N1.Fc1ccc(CBr)cc1>>CCOC(=O)C1CCC(=O)N1Cc1ccc(F)cc1 -US20140275006A1,2,CCOC(=O)CC(=O)NN.O=C=Nc1cccc(C(F)(F)F)c1>>CCOC(=O)CC(=O)NNC(=O)Nc1cccc(C(F)(F)F)c1 -US20080076774A1,7,Cc1c(OCc2ccccc2)cccc1[N+](=O)[O-]>>Cc1c(N)cccc1OCc1ccccc1 -US05236927,1,C=CCNc1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)cc1.CC(C)(C)C(=O)OCn1cnc2ccc(CBr)cc2c1=O>>C=CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)cc1 -US20140206660A1,3,CCCC(=O)Cc1ccc(OCc2ccccc2)cc1.CCOC(=O)C=O>>CCCC(=O)C(c1ccc(OCc2ccccc2)cc1)C(O)C(=O)OCC -US20090325964A1,1,COc1ccc(C(=O)N2CCNCC2)cc1C#Cc1ccccn1.N#Cc1cnc(Cl)nc1N>>COc1ccc(C(=O)N2CCN(c3ncc(C#N)c(N)n3)CC2)cc1C#Cc1ccccn1 -US05366987,2,COc1cc(OC)c(N)c(OC)c1.N#CC(CC(=O)O)c1ccccc1>>COc1cc(OC)c(NC(=O)CC(C#N)c2ccccc2)c(OC)c1 -US20040058978A1,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)NCCc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccc(CN)cc2)cc1>>CC(=O)NCc1ccc(/C(Nc2ccc(CCNC(=O)OC(C)(C)C)cc2)=C2/C(=O)Nc3ccc([N+](=O)[O-])cc32)cc1 -US20100210619A1,7,CCOC(=O)CCCS(=O)(=O)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)CCCS(=O)(=O)c1ccc(N)cc1 -US20110009435A1,2,CC(=O)Cl.COc1cccc(CNC(=O)c2nc3scc(COC[C@@H]4CC[C@@H](N)CC4)c3c(=O)[nH]2)c1>>COc1cccc(CNC(=O)c2nc3scc(COC[C@@H]4CC[C@@H](NC(C)=O)CC4)c3c(=O)[nH]2)c1 -US20090082372A1,2,COc1ccc2nc(-c3ccc(OC)c(F)c3)nc(C(=O)O)c2c1.NC(CO)Cc1c[nH]c2cccnc12>>COc1ccc2nc(-c3ccc(OC)c(F)c3)nc(C(=O)NC(CO)Cc3c[nH]c4cccnc34)c2c1 -US20150274753A1,6,C=C(CCl)COc1ccc(CNc2nc(Nc3ccc(C(=O)NCC(C)(C)CNC(=O)OC(C)(C)C)cc3)nc(OCC(F)(F)F)n2)cc1>>C=C(CCl)COc1ccc(CNc2nc(Nc3ccc(C(=O)NCC(C)(C)CN)cc3)nc(OCC(F)(F)F)n2)cc1 -US20050107606A1,8,CCCn1cncc1CSc1ccc(N)cc1.OO>>CCCn1cncc1CS(=O)c1ccc(N)cc1 -US20130029954A1,6,C=C(C)[C@@H]1CC[C@]2(CNCCc3ccc(C(=O)OC)cc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(CNCCc3ccc(C(=O)O)cc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20070287699A1,1,CNC.N#Cc1cn(Cc2ccc(C(F)(F)F)cc2)c2cc(F)c(F)cc2c1=O>>CN(C)c1cc2c(cc1F)c(=O)c(C#N)cn2Cc1ccc(C(F)(F)F)cc1 -US20110098323A1,3,CCOc1cc(C=O)ccc1O.COC(=O)c1cccc(N2C(=O)CSC2=S)c1>>CCOc1cc(C=C2SC(=S)N(c3cccc(C(=O)OC)c3)C2=O)ccc1O -US08288410B2,1,FC(F)(F)c1ccccc1S.Ic1cnc2ccccc2c1>>FC(F)(F)c1ccccc1Sc1cnc2ccccc2c1 -US20070185103A1,2,CC(=O)Cl.CCOC(=O)C1CNCC(CC2CCCCC2)C1>>CCOC(=O)C1CC(CC2CCCCC2)CN(C(C)=O)C1 -US20150175561A1,9,CC(C)(C)OC(=O)NC(CC(=O)OCc1ccccc1)C(=O)O.N>>CC(C)(C)OC(=O)NC(CC(=O)OCc1ccccc1)C(N)=O -US08680120B2,9,BrC(Br)(Br)Br.CCOc1ccc([N+](=O)[O-])c(C=O)c1>>CCOc1ccc([N+](=O)[O-])c(C=C(Br)Br)c1 -US06548495B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2ccnc2)c1.Cc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>Cc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3ccnc3)c2)cc1C(F)(F)F -US08304556B2,1,CC(C)(C)OC(=O)NN.CCC(=O)CC>>CCC(CC)=NNC(=O)OC(C)(C)C -US20070167406A1,3,CCOC(=O)CC#N.N#Cc1ccc(C=O)cc1>>CCOC(=O)/C(C#N)=C\c1ccc(C#N)cc1 -US08361962B2,1,C#CCCl.CC1CCCCN1>>C#CCN1CCCCC1C -US20110160180A1,2,CC(C)(C)OC(=O)NC1CCNCC1.Cn1c2c(c3cc(C(=O)O)ccc31)CC(C1CCOCC1)CC2>>Cn1c2c(c3cc(C(=O)N4CCC(NC(=O)OC(C)(C)C)CC4)ccc31)CC(C1CCOCC1)CC2 -US07625909B2,7,CCOC(=O)[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)CCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1CO -US20040067933A1,6,CCCCC1(CCCC)CN(c2ccc(Cl)cc2)c2cc(SC)c(OCC(=O)OCC)cc2S(=O)(=O)C1>>CCCCC1(CCCC)CN(c2ccc(Cl)cc2)c2cc(SC)c(OCC(=O)O)cc2S(=O)(=O)C1 -US20070060607A1,9,CCOC(=O)c1cnc(Cl)c2c(COc3cccc(NS(=O)(=O)c4ccc(Cl)cc4)c3)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3cccc(NS(=O)(=O)c4ccc(Cl)cc4)c3)csc12 -US08962671B2,2,Cc1ccccc1[C@@H](N)CC(=O)O.Nc1cc(C(=O)O)nn1-c1ccccc1>>Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(N)n(-c2ccccc2)n1 -US20090247567A1,6,COC(=O)c1ccc2c(c1)-c1sc(C(=O)N(C)c3ccc(F)cc3F)cc1CO2>>CN(C(=O)c1cc2c(s1)-c1cc(C(=O)O)ccc1OC2)c1ccc(F)cc1F -US07432392B2,7,CN(C)C(=O)c1cc(OCc2ccccc2)c(F)cc1[N+](=O)[O-]>>CN(C)C(=O)c1cc(OCc2ccccc2)c(F)cc1N -US20090227555A2,1,CC1(C(=O)O)CCNCC1.CCOC(=O)c1cc(C#N)c(Cl)nc1C>>CCOC(=O)c1cc(C#N)c(N2CCC(C)(C(=O)O)CC2)nc1C -US20140113922A1,7,CCOC(=O)/C=C/c1ccc(C#N)cc1>>CCOC(=O)CCc1ccc(C#N)cc1 -US20120165306A1,6,CC(C)(C)OC(=O)N1CCC[C@H](C(=O)Nc2cc(-c3cncc(NCC4CCOCC4)n3)c(Cl)cn2)C1>>O=C(Nc1cc(-c2cncc(NCC3CCOCC3)n2)c(Cl)cn1)[C@H]1CCCNC1 -US08309546B2,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.Clc1nc(N2CCOCC2)c2ncn(CC3CC3)c2n1>>Nc1ncc(-c2nc(N3CCOCC3)c3ncn(CC4CC4)c3n2)cn1 -US07238716B2,1,COC(=O)c1cccc(Cl)n1.Cc1oc(-c2ccccc2)nc1CO>>COC(=O)c1cccc(OCc2nc(-c3ccccc3)oc2C)n1 -US20050043292A1,6,CC(C)(C)OC(=O)NC(CCCCNC(=O)OCc1ccccc1)C(=O)N1CC(F)(F)C(F)(F)C1>>NC(CCCCNC(=O)OCc1ccccc1)C(=O)N1CC(F)(F)C(F)(F)C1 -US20130317024A1,1,COC(=O)c1cc(-c2cnc(OC)nc2OC)n(C(C)C)c1C(O)c1ccc(C#N)c(F)c1.Cn1cc(N)cc(Cl)c1=O>>COC(=O)c1cc(-c2cnc(OC)nc2OC)n(C(C)C)c1C(Nc1cc(Cl)c(=O)n(C)c1)c1ccc(C#N)c(F)c1 -US08178668B2,2,COC(=O)C(OC)OC.NCc1cc(Cl)c(F)cc1F>>COC(OC)C(=O)NCc1cc(Cl)c(F)cc1F -US06156700,6,CCOC(=O)Cc1nsc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc12>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(CC(=O)O)c3c2)c1=O -US08470819B2,1,N#Cc1ccc(F)c([N+](=O)[O-])c1.Nc1ccc(OC(F)(F)F)cc1>>N#Cc1ccc(Nc2ccc(OC(F)(F)F)cc2)c([N+](=O)[O-])c1 -US08637510B2,3,C[C@H]1CN(c2nc(C#N)c(Br)s2)C[C@@H](C)O1.Cc1cc(B(O)O)cc(C)n1>>Cc1cc(-c2sc(N3C[C@H](C)O[C@H](C)C3)nc2C#N)cc(C)n1 -US07135487B2,2,CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(CCN)cc2)cc1.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)NCCc2ccc(-c3ccc(C(C)CNS(=O)(=O)C(C)C)cc3)cc2)c1 -US20060106048A1,6,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(CC(=O)OC)cc1)=NC(C)(C)C2>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(CC(=O)O)cc1)=NC(C)(C)C2 -US20090143385A1,2,NC1CC1.O=C(O)c1ccc(OCc2conc2-c2ccccn2)nn1>>O=C(NC1CC1)c1ccc(OCc2conc2-c2ccccn2)nn1 -US05179125,1,CC(C)COC(=O)Cl.Cc1c(NC(=O)C(CS)Cc2ccccc2)cccc1C(=O)O>>Cc1c(NC(=O)C(CSC(=O)OCC(C)C)Cc2ccccc2)cccc1C(=O)O -US04167568,4,CCCOc1ccc(C#N)cc1C1=NC(=O)C2=NN=NC2=N1.[N-]=[N+]=[N-]>>CCCOc1ccc(-c2nnn[nH]2)cc1C1=NC(=O)C2=NN=NC2=N1 -US20030207927A1,7,COc1ccc(C(=O)c2ccc(OC)cc2F)c(C)c1>>COc1ccc(C(O)c2ccc(OC)cc2F)c(C)c1 -US20100216813A1,1,CN1CC[C@H](Nc2ccc(C#N)c(Cl)c2)C1.Fc1ccc(CBr)c(C(F)(F)F)c1>>CN1CC[C@H](N(Cc2ccc(F)cc2C(F)(F)F)c2ccc(C#N)c(Cl)c2)C1 -US07423044B2,1,CC(C)c1cc(O)nc(-c2cccc([N+](=O)[O-])c2)n1.FC(F)(F)c1ccc(CBr)cc1>>CC(C)c1cc(OCc2ccc(C(F)(F)F)cc2)nc(-c2cccc([N+](=O)[O-])c2)n1 -US20110098301A1,6,COc1ccc(-c2cc(Nc3ccc(Oc4ccnc(C)c4)cc3)nc(N)n2)cc1>>Cc1cc(Oc2ccc(Nc3cc(-c4ccc(O)cc4)nc(N)n3)cc2)ccn1 -US06562849B1,2,CCCCCCNc1ccc(Oc2ccc3nc(COc4ccc(CC5SC(=O)NC5=O)cc4)n(C)c3c2)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>CCCCCCN(C(=O)Nc1ccc(C(F)(F)F)cc1)c1ccc(Oc2ccc3nc(COc4ccc(CC5SC(=O)NC5=O)cc4)n(C)c3c2)cc1 -US08481731B2,6,CN(c1cc(N2CCc3cc(S(C)(=O)=O)ccc32)ncn1)C1CCN(Cc2ccccc2)CC1>>CN(c1cc(N2CCc3cc(S(C)(=O)=O)ccc32)ncn1)C1CCNCC1 -US04675392,9,CC(=O)OC[C@H]1O[C@H](O[C@@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](O[C@H]3[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OCCBr)O[C@@H]3COC(C)=O)O[C@@H]2COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O>>CCO[C@@H]1O[C@H](COC(C)=O)[C@@H](O[C@@H]2O[C@H](COC(C)=O)[C@H](O[C@H]3O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O -US20030171396A1,1,CC(=O)Oc1ccc(CBr)c(Cl)c1.COC(=O)c1cc(C)c2nc(C)[nH]c2n1>>COC(=O)c1cc(C)c2nc(C)n(Cc3ccc(OC(C)=O)cc3Cl)c2n1 -US04292431,7,COC(=O)c1cncn1Cc1ccccc1>>OCc1cncn1Cc1ccccc1 -US08309734B2,2,O=C(O)c1cc(F)cnc1Oc1ccc(F)c(Cl)c1.c1ccc2c(c1)CCCN2>>O=C(c1cc(F)cnc1Oc1ccc(F)c(Cl)c1)N1CCCc2ccccc21 -US08022099B2,6,CN(C(=O)OC(C)(C)C)C1CN(C(=O)N2CCN(S(C)(=O)=O)CC2)CC1c1ccc(Cl)cc1>>CNC1CN(C(=O)N2CCN(S(C)(=O)=O)CC2)CC1c1ccc(Cl)cc1 -US06586617B1,1,CCI.CSc1ccc(NS(=O)(=O)c2ccc(C)cc2)c([N+](=O)[O-])c1>>CCN(c1ccc(SC)cc1[N+](=O)[O-])S(=O)(=O)c1ccc(C)cc1 -US20140066459A1,3,CC(=O)N1c2ccc(Br)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.COCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COCCn1cc(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)cn1 -US05457106,1,O=C1c2ccccc2C(=O)N1CCCCBr.Oc1ccncc1>>O=C1c2ccccc2C(=O)N1CCCCOc1ccncc1 -US05495020,1,CCOC(=O)C(=CNC1CC1)C(=O)c1c(C)c(F)c(F)c(Cl)c1F>>CCOC(=O)c1cn(C2CC2)c2c(Cl)c(F)c(F)c(C)c2c1=O -US20100130737A1,6,CCOC(=O)c1cc2cc(-c3ccc(OC)cc3)ccc2s1>>COc1ccc(-c2ccc3sc(C(=O)O)cc3c2)cc1 -US07432283B2,2,CCC(=O)Cl.Cc1cc(C)c(N2CCCc3c2nn(C)c3N)c(Cl)c1>>CCC(=O)Nc1c2c(nn1C)N(c1c(C)cc(C)cc1Cl)CCC2 -US20020006946A1,4,Cc1cc(NC#N)cc(C)c1Oc1ccc(O)c(S(=O)(=O)CC2CC2)c1.[N-]=[N+]=[N-]>>Cc1cc(Nc2nnn[nH]2)cc(C)c1Oc1ccc(O)c(S(=O)(=O)CC2CC2)c1 -US20070054884A1,2,Fc1ccc(N=C=S)cc1.Nc1cc(Oc2ccc(Cl)cc2Cl)c(O)cc1Cl>>Oc1cc(Cl)c(NC(=S)Nc2ccc(F)cc2)cc1Oc1ccc(Cl)cc1Cl -US20090163586A1,2,COc1cc(N)c(S(N)(=O)=O)cc1F.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>COc1cc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(S(N)(=O)=O)cc1F -US20100041891A1,5,COCCl.Oc1cccnc1I>>COCOc1cccnc1I -US20140186771A1,2,C=C(C)C(=O)Cl.OC1C=CCC1>>C=C(C)C(=O)OC1C=CCC1 -US08143290B2,6,CC(=O)n1ncc2cc(I)c(C)cc21>>Cc1cc2[nH]ncc2cc1I -US04882447,2,CCOC(=O)C(N)C(=O)OCC.O=C(O)CO>>CCOC(=O)C(NC(=O)CO)C(=O)OCC -US08003648B2,2,Nc1cccc(COc2ccc([C@H](CC(=O)N3C(=O)OC[C@@H]3Cc3ccccc3)c3ccon3)cc2)c1.O=C(Cl)c1ccc(C(F)(F)F)cc1>>O=C(Nc1cccc(COc2ccc([C@H](CC(=O)N3C(=O)OC[C@@H]3Cc3ccccc3)c3ccon3)cc2)c1)c1ccc(C(F)(F)F)cc1 -US20060122197A1,7,CC(C)(C)OC(=O)N1CCC[C@H](NC(=O)C23CC4CC(C2)C(=O)C(C4)C3)C1>>CC(C)(C)OC(=O)N1CCC[C@H](NC(=O)C23CC4CC(C2)C(O)C(C4)C3)C1 -US20110110889A1,2,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)O)c1F.CCc1cc2cc(N)cnc2[nH]1>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]c(CC)cc3c2)c1F -US06759408B2,3,CN(C)C=O.Cc1ccsc1Br>>Cc1cc(C=O)sc1Br -US07863293B2,2,CC(C)(C)OC(=O)NC(CSC(=O)OC(C)(C)C)C(=O)O.Cc1cccnc1CN(Cc1ncccc1C)C1CCNCC1>>Cc1cccnc1CN(Cc1ncccc1C)C1CCN(C(=O)C(CSC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)CC1 -US20150018332A1,2,NCc1cncnc1.O=C(O)/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1>>O=C(/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)NCc1cncnc1 -US20110086834A1,2,Brc1ccc2c(c1)NCC21CCSCC1.CC(=O)Cl>>CC(=O)N1CC2(CCSCC2)c2ccc(Br)cc21 -US20150057265A1,3,COC(=O)c1sc2cc(Br)cnc2c1NC(=O)OC(C)(C)C.O=C(OCc1ccccc1)N1CC(I)C1>>COC(=O)c1sc2cc(C3CN(C(=O)OCc4ccccc4)C3)cnc2c1NC(=O)OC(C)(C)C -US20030144507A1,1,CNC.O=S(=O)(Nc1ccc2c(Cl)nccc2c1)c1ccc(Cl)cc1>>CN(C)c1nccc2cc(NS(=O)(=O)c3ccc(Cl)cc3)ccc12 -US20120172599A1,3,CCCCN(CCCC)c1ccc(C=Cc2cccs2)c(OC)c1.CN(C)C=O>>CCCCN(CCCC)c1ccc(C=Cc2ccc(C=O)s2)c(OC)c1 -USRE030241,2,CCCCCCCCCCCCCCC(C)(C)CC(=O)Cl.COc1c(C)ccc(C(=O)Oc2ccc(C(=O)CNC(C)C)cc2O)c1Cl>>CCCCCCCCCCCCCCC(C)(C)CC(=O)Oc1cc(C(=O)CNC(C)C)ccc1OC(=O)c1ccc(C)c(OC)c1Cl -US20120269766A1,9,C#CCOCCOCCOCCOCCN=[N+]=[N-]>>C#CCOCCOCCOCCOCCN -US20150018343A1,6,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OCCN(C)C(=O)OC(C)(C)C)C3>>CNCCOc1ccccc1C(=O)N1Cc2nn3c(C)c(Cl)c(C)nc3c2C1 -US20130261114A1,7,Cc1ccccc1C(=O)C1CN2CCC1CC2>>Cc1ccccc1C(O)C1CN2CCC1CC2 -US20080194629A1,6,CC1(CNCc2ccccc2)c2ccccc2Oc2ccccc21>>CC1(CN)c2ccccc2Oc2ccccc21 -US20100076014A1,6,COC(=O)C(C)(C)Cc1cc2cnn(-c3ccc(F)cc3)c2cc1C>>Cc1cc2c(cnn2-c2ccc(F)cc2)cc1CC(C)(C)C(=O)O -US08377895B2,3,C=O.COc1c(O)cc(O)c2c(=O)cc(-c3ccccc3)oc12.OC1CCNCC1>>COc1c(O)c(CN2CCC(O)CC2)c(O)c2c(=O)cc(-c3ccccc3)oc12 -US07126012B2,1,CC(=O)C(Br)c1ccccc1.Sc1ccc(Cl)cc1>>CC(=O)C(Sc1ccc(Cl)cc1)c1ccccc1 -US20020193367A1,7,CC(C)(C)OC(=O)Nc1cc(N2CCCC2)c(C(F)(F)F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(N2CCCC2)c(C(F)(F)F)cc1N -US20110268698A1,1,CC(C)S(=O)(=O)NC(=O)Nc1ccc(-c2c(C#N)c3ccc(O)cc3n2C2CCC2)cc1.Clc1ncccn1>>CC(C)S(=O)(=O)NC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)cc1 -US04959361,3,C#CCN1C(=O)CCc2ccccc21.COC1N=C(c2ccccc2F)c2cc(I)ccc2-n2c(C)nnc21>>COC1N=C(c2ccccc2F)c2cc(C#CCN3C(=O)CCc4ccccc43)ccc2-n2c(C)nnc21 -US04115568,1,CCOC(=O)c1cc(CC)sc1N.O=[N+]([O-])c1cccc(Cl)c1F>>CCOC(=O)c1cc(CC)sc1Nc1c(Cl)cccc1[N+](=O)[O-] -US06903115B2,7,CCOc1cc(C(=O)O)ccc1[N+](=O)[O-]>>CCOc1cc(C(=O)O)ccc1N -US20080125424A1,6,CC(C)(C)OC(=O)CCCN(CCC(c1ccccc1)c1ccccc1)C(=O)Nc1nc(-c2ccc(NS(C)(=O)=O)cc2)cs1>>CS(=O)(=O)Nc1ccc(-c2csc(NC(=O)N(CCCC(=O)O)CCC(c3ccccc3)c3ccccc3)n2)cc1 -US20100280048A1,9,COC(=O)c1nc(-c2ccnn2-c2ccc(Cl)cc2)c(C)n(-c2cccc(C(F)(F)F)c2)c1=O.N>>Cc1c(-c2ccnn2-c2ccc(Cl)cc2)nc(C(N)=O)c(=O)n1-c1cccc(C(F)(F)F)c1 -US20150038528A1,2,COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O.N#Cc1ccc([C@@H](N)CC(=O)O)cc1>>N#Cc1ccc([C@H](CC(=O)O)NC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)cc1 -US07569568B2,4,C#CC(=O)OC.Cc1ccc(C(=O)O)cc1N=[N+]=[N-]>>COC(=O)c1cn(-c2cc(C(=O)O)ccc2C)nn1 -US05733914,1,Clc1cccc(Cl)c1CBr.Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)[nH]c2n1>>Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(Cc3c(Cl)cccc3Cl)c2n1 -US07989449B2,1,BrCCOC1CCCCO1.C=C(c1ccc(O)cc1)c1cccc(Br)c1>>C=C(c1ccc(OCCOC2CCCCO2)cc1)c1cccc(Br)c1 -US20090115320A1,1,CC1(C)c2cc(Br)ccc2-c2ccc(I)cc21.c1ccc(Nc2ccccc2)cc1>>CC1(C)c2cc(Br)ccc2-c2ccc(N(c3ccccc3)c3ccccc3)cc21 -US08901118B2,1,COC(=O)c1ccc(F)nc1F.COc1ccc(N)cn1>>COC(=O)c1ccc(Nc2ccc(OC)nc2)nc1F -US20110046134A1,6,O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cc(-c2cccc(OCc3ccccc3)c2)on1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cc(-c2cccc(O)c2)on1 -US08119563B2,1,COCCOc1ccc(C=O)cc1.OC1(C(c2ccc(OC(F)(F)F)cc2)c2ccc(OC(F)(F)F)cc2)CCNCC1>>COCCOc1ccc(CN2CCC(O)(C(c3ccc(OC(F)(F)F)cc3)c3ccc(OC(F)(F)F)cc3)CC2)cc1 -US20080027050A1,3,COc1cccc(CNC(=O)c2nc3ccc(I)cc3c(=O)[nH]2)c1.OB(O)c1ccccc1>>COc1cccc(CNC(=O)c2nc3ccc(-c4ccccc4)cc3c(=O)[nH]2)c1 -US07846964B2,2,CS(=O)(=O)Cl.Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCO>>Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCOS(C)(=O)=O -US20150175541A1,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCC(c2ccccc2)CC1>>COC=C1CCC(c2ccccc2)CC1 -US07196202B2,1,CCCI.COC(=O)CCCCCOc1ccc2nc(S)n(-c3ccccc3)c2c1>>CCCSc1nc2ccc(OCCCCCC(=O)OC)cc2n1-c1ccccc1 -US20080146616A1,3,CC1(C)OB(c2cccnc2)OC1(C)C.CCOC(=O)c1[nH]c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1I>>CCOC(=O)c1[nH]c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1-c1cccnc1 -US20090306062A1,2,COCCCN1CCOc2ccc(CO[C@@H]3CC[C@@H](CC(C)(C)C(=O)O)N(S(=O)(=O)c4ccc(C)cc4)C3)cc21.NC1CCOCC1>>COCCCN1CCOc2ccc(CO[C@@H]3CC[C@@H](CC(C)(C)C(=O)NC4CCOCC4)N(S(=O)(=O)c4ccc(C)cc4)C3)cc21 -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NC[C@H]1CCNC[C@H]1OC.O=C(CCCCCBr)c1ccccc1>>COc1cc(N)c(Cl)cc1C(=O)NC[C@H]1CCN(CCCCCC(=O)c2ccccc2)C[C@H]1OC -US08158790B2,2,CCC[C@@H]1C[C@@H]([C@H](O)COCc2ccccc2)OC1=O.CS(=O)(=O)Cl>>CCC[C@@H]1C[C@@H]([C@@H](COCc2ccccc2)OS(C)(=O)=O)OC1=O -US08097634B2,2,CC(C)(C)CC(=O)Cl.O=C1CC2(CCN1)CCN(c1ccc(CC(F)(F)F)cc1)C2=O>>CC(C)(C)CC(=O)N1CCC2(CCN(c3ccc(CC(F)(F)F)cc3)C2=O)CC1=O -US20110237581A1,6,C[C@@H]1CN(Cc2ccc(C3Nc4cccc5c(=O)[nH]nc(c45)C3c3ccc(F)cc3)cc2)C[C@@H](C)N1C(=O)OC(C)(C)C>>CC1CN(Cc2ccc(C3Nc4cccc5c(=O)[nH]nc(c45)C3c3ccc(F)cc3)cc2)CC(C)N1 -US06096763,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1CCNCC1>>CC(C)(C)OC(=O)N1CCC(=O)CC1 -US20090076274A1,1,COC(=O)CBr.O=[N+]([O-])c1cc(Br)ccc1O>>COC(=O)COc1ccc(Br)cc1[N+](=O)[O-] -US08779158B2,1,C[O-].Nc1cc(F)c(F)c(F)c1>>COc1cc(N)cc(F)c1F -US20060155121A1,2,CCCOC(=O)Cl.Cc1cc(Br)cc(C)c1N>>CCCOC(=O)Nc1c(C)cc(Br)cc1C -US06355680B1,1,COc1ccc(N)cc1.O=C(O)Cc1ccccc1Br>>COc1ccc(Nc2ccccc2CC(=O)O)cc1 -US20110306590A1,1,Clc1cc(C2CCOCC2)ncn1.Clc1ccc2[nH]c(C3CNC3)nc2c1>>Clc1ccc2[nH]c(C3CN(c4cc(C5CCOCC5)ncn4)C3)nc2c1 -US07897612B2,1,CC(C)(C)c1ccc(CN)cc1.CCOC(=O)c1cccnc1Cl>>CCOC(=O)c1cccnc1NCc1ccc(C(C)(C)C)cc1 -US04334015,1,NNC(=O)c1ccccc1N.O=Cc1c(O)ccc2ccccc12>>Nc1ccccc1C(=O)NN=Cc1c(O)ccc2ccccc12 -US20110105436A1,3,C#CCO.Cc1cccc(Nc2nc(-c3ccnc(Br)c3)cs2)c1>>Cc1cccc(Nc2nc(-c3ccnc(C#CCO)c3)cs2)c1 -US08158560B2,2,NC1CSC1.O=C(O)c1ccc(C2=NCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1C(F)(F)F>>O=C(NC1CSC1)c1ccc(C2=NCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1C(F)(F)F -US20100022486A1,6,Cc1cc(NC(=O)c2ccc3c(c2)CCN(C(=O)OC(C)(C)C)C3)nn1Cc1ccccc1-c1ccccc1>>Cc1cc(NC(=O)c2ccc3c(c2)CCNC3)nn1Cc1ccccc1-c1ccccc1 -US20070049604A1,1,NCCN1CCN(c2ccc([N+](=O)[O-])cc2)CC1.O=Cc1cc(-c2ccco2)n(-c2ccccc2)n1>>O=[N+]([O-])c1ccc(N2CCN(CCNCc3cc(-c4ccco4)n(-c4ccccc4)n3)CC2)cc1 -US07176310B1,2,O=C(O)COc1ncc(C(=O)Nc2ccc(F)cc2)cn1.OCCC12CC3CC(CC(C3)C1)C2>>O=C(COc1ncc(C(=O)Nc2ccc(F)cc2)cn1)OCCC12CC3CC(CC(C3)C1)C2 -US05736487,1,COC(=O)Nc1ccc(O)cc1C.COc1ccc2nc(CBr)sc2c1>>COC(=O)Nc1ccc(OCc2nc3ccc(OC)cc3s2)cc1C -US07880042B2,1,COc1c(F)cccc1[C@H](C)C[C@@](O)(C=O)C(F)(F)F.Nc1ccc(F)c2[nH]c(=O)ccc12>>COc1c(F)cccc1[C@H](C)C[C@@](O)(C=Nc1ccc(F)c2[nH]c(=O)ccc12)C(F)(F)F -US20100076145A1,1,CCCCC(CC)CNCC(CC)CCCC.ClCC1CO1>>CCCCC(CC)CN(CC(CC)CCCC)CC1CO1 -US06140332,1,COc1ccccc1-c1cc2c(Cl)ncnc2[nH]1.Nc1cccc(Cl)c1>>COc1ccccc1-c1cc2c(Nc3cccc(Cl)c3)ncnc2[nH]1 -US20150232463A1,3,CN1CC(=O)OB(c2ccc(OCCc3ccc(F)cc3)cc2)OC(=O)C1.COC1(C)CCN(c2c(Br)c(C)nc(C)c2[C@H](OC(C)(C)C)C(=O)OC(C)C)CC1>>COC1(C)CCN(c2c(-c3ccc(OCCc4ccc(F)cc4)cc3)c(C)nc(C)c2[C@H](OC(C)(C)C)C(=O)OC(C)C)CC1 -US20120289522A1,1,CC(C)Cl.Oc1cncc(Br)c1>>CC(C)Oc1cncc(Br)c1 -US04997956,1,C=C(C)Cc1cccc(C(=O)OC)c1O.CN(C)C(=S)Cl>>C=C(C)Cc1cccc(C(=O)OC)c1OC(=S)N(C)C -US20110224203A1,6,CCOc1cc2[nH]c(-c3n[nH]cc3NC(=O)c3c(F)cccc3F)nc2cc1C(=O)OC>>CCOc1cc2[nH]c(-c3n[nH]cc3NC(=O)c3c(F)cccc3F)nc2cc1C(=O)O -US05360808,6,COC(=O)c1ccc(=O)n(CCCNC(=O)c2ccccn2)c1>>O=C(O)c1ccc(=O)n(CCCNC(=O)c2ccccn2)c1 -US20130023541A1,8,OCCCc1c(F)cccc1Cl>>O=CCCc1c(F)cccc1Cl -US20080039455A1,1,COc1cc(-c2cnn3ccc(Cl)nc23)cc(OC)c1OC.Nc1ccc(F)cc1>>COc1cc(-c2cnn3ccc(Nc4ccc(F)cc4)nc23)cc(OC)c1OC -US20150274720A1,7,COc1ccc(CNc2nccc(Cl)c2[N+](=O)[O-])c(OC)c1>>COc1ccc(CNc2nccc(Cl)c2N)c(OC)c1 -US07247625B2,1,CN1C(=O)OC(C)(C)c2cc(N)ccc21.OB(O)c1ccccc1Cl>>CN1C(=O)OC(C)(C)c2cc(Nc3ccccc3Cl)ccc21 -US08822534B2,7,CCOC(=O)/C(C)=C/[C@@H](C)NC(=O)OC(C)(C)C>>CCOC(=O)[C@H](C)C[C@@H](C)NC(=O)OC(C)(C)C -US05500427,1,CCOC(=O)c1cn(C)nc1N.N#Cc1ccccc1-c1ccc(CBr)cc1>>CCOC(=O)c1cn(C)nc1NCc1ccc(-c2ccccc2C#N)cc1 -US04636511,6,O=C(NCCO)NCc1ccccc1OCc1ccccc1>>O=C(NCCO)NCc1ccccc1O -US20090192154A1,3,CCC(C(=O)OC)N1Cc2sc(-c3ccc(Br)cc3)cc2S1(=O)=O.Cn1ccc2cc(B(O)O)ccc21>>CCC(C(=O)OC)N1Cc2sc(-c3ccc(-c4ccc5c(ccn5C)c4)cc3)cc2S1(=O)=O -US20130296312A1,1,CC(C)(C)OC(=O)N1CCN(c2cccc(N)c2)CC1.COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Cl)nc12>>COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3cccc(N4CCN(C(=O)OC(C)(C)C)CC4)c3)nc12 -US20150266883A1,3,C#CC1CCN(C(=O)OC(C)(C)C)CC1.CCCCc1nc(N)c2c(n1)c(I)cn2COCc1ccccc1>>CCCCc1nc(N)c2c(n1)c(C#CC1CCN(C(=O)OC(C)(C)C)CC1)cn2COCc1ccccc1 -US06492360B1,3,Brc1ccncc1.C#Cc1c(OC)ccc2c(=O)[nH]ncc12>>COc1ccc2c(=O)[nH]ncc2c1C#Cc1ccncc1 -US20140275026A1,1,N#Cc1ccc(O)cc1.O=[N+]([O-])c1ccc(F)c(Br)c1>>N#Cc1ccc(Oc2ccc([N+](=O)[O-])cc2Br)cc1 -US06548493B1,1,CCCCBr.Clc1ccc(-c2cc3c4c(c2)[C@@H]2CNCC[C@@H]2N4CCC3)c(Cl)c1>>CCCCN1CC[C@H]2[C@@H](C1)c1cc(-c3ccc(Cl)cc3Cl)cc3c1N2CCC3 -US07105507B2,3,CC(C(=O)NC1(c2ccccc2)CCC(=O)CC1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1CCC(NC(=O)C(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1 -US04092356,9,CCCCC(C)(C)C(CCCC(CCCCCCC(=O)OCC)(C(C)=O)C(=O)OC(C)(C)C)OC(C)=O>>CCCCC(C)(C)C(CCCC(CCCCCCC(=O)OCC)C(C)=O)OC(C)=O -US08034811B2,2,C=C(C)C(=O)OCCN=C=O.Nc1cc(Cn2c(=O)oc(=O)c3ccccc32)ccn1>>C=C(C)C(=O)OCCNC(=O)Nc1cc(Cn2c(=O)oc(=O)c3ccccc32)ccn1 -US20090227628A1,7,Cc1ccc(CNc2ccc3c(C=O)cccc3n2)o1>>Cc1ccc(CNc2ccc3c(CO)cccc3n2)o1 -US09133168B2,2,CC1Cc2c(Br)cccc2N1.O=C([O-])Cc1nc(N2CCOCC2)c(F)c(=O)[nH]1>>CC1Cc2c(Br)cccc2N1C(=O)Cc1nc(N2CCOCC2)c(F)c(=O)[nH]1 -US20150258074A1,1,Cc1nc(Cl)cc2[nH][nH]c(=O)c12.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1nc(Cl)cc2c1c(=O)[nH]n2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20100093757A1,2,COC[C@@H](C)OC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)OC.Cc1ccc(N)nc1>>COC[C@@H](C)OC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(C)cn1 -US20070191385A1,1,O=C1CN(c2ccc(-n3cc(-c4ccc(Cl)cc4Cl)nc3Cc3ccc(-c4ccc(Br)cc4)cc3)cc2)S(=O)(=O)N1.O=C1CNCCN1>>O=C1CN(c2ccc(-c3ccc(Cc4nc(-c5ccc(Cl)cc5Cl)cn4-c4ccc(N5CC(=O)NS5(=O)=O)cc4)cc3)cc2)CCN1 -US20100168102A9,2,CC(C)(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccc(C(=O)O)cc1.Nc1ccncc1>>CC(C)(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccc(C(=O)Nc2ccncc2)cc1 -US20060142576A1,3,COC(=O)CC(C)=O.O=Cc1ccc(Cl)cc1Cl>>COC(=O)C(=Cc1ccc(Cl)cc1Cl)C(C)=O -US06541467B1,9,N#Cc1ccc(CBr)s1.[N-]=[N+]=[N-]>>N#Cc1ccc(CN=[N+]=[N-])s1 -US20130018030A1,3,CC(C)(C)OC(=O)N1CCC([C@H]2Cc3cc(Cl)ncc3O2)CC1.CC1(C)OB(C2=CCN(S(C)(=O)=O)CC2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC([C@H]2Cc3cc(C4=CCN(S(C)(=O)=O)CC4)ncc3O2)CC1 -US20090156572A1,1,BrCc1ccccc1.CCOC(=O)CCNCC(C(=O)OCC)c1ccc(Cl)c(Cl)c1>>CCOC(=O)CCN(Cc1ccccc1)CC(C(=O)OCC)c1ccc(Cl)c(Cl)c1 -US20130217702A1,6,CC(C)(C)OC(=O)NCc1ccc(-n2c(C#N)c(Cl)c3ccccc32)cc1>>N#Cc1c(Cl)c2ccccc2n1-c1ccc(CN)cc1 -US20090239880A1,7,c1ccc(C(=C2CCN(c3nc4ccccc4[nH]3)CC2)c2ccccc2)cc1>>c1ccc(C(c2ccccc2)C2CCN(c3nc4ccccc4[nH]3)CC2)cc1 -US20080070948A1,1,CC1CCNCC1.O=c1oc2ccccc2n1CCCCCl>>CC1CCN(CCCCn2c(=O)oc3ccccc32)CC1 -US20040038239A1,5,COCCl.O=Cc1ccc(OCc2ccccc2)cc1O>>COCOc1cc(OCc2ccccc2)ccc1C=O -US07625901B2,1,CCOC(=O)CBr.O=C1CO[C@H]2Cc3ccccc3[C@H]2N1>>CCOC(=O)CN1C(=O)CO[C@H]2Cc3ccccc3[C@H]21 -US20050131014A1,3,CCOC(=O)c1cnc2c(C(F)(F)F)cccc2c1Cl.Nc1cccc(B(O)O)c1>>CCOC(=O)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(N)c1 -US20100124550A1,9,COCCCOc1cc(C(O)[C@@H](C/C=C/C[C@H](C(=O)N(C)C)C(C)C)C(C)C)ccc1OC>>COCCCOc1cc(C[C@@H](C/C=C/C[C@H](C(=O)N(C)C)C(C)C)C(C)C)ccc1OC -US20120316147A1,2,CC(C)C[C@H](N)C(N)=O.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>CC(C)C[C@H](NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(N)=O -US06365598B1,1,C[O-].Cc1ccc2c(Cl)nccc2c1[N+](=O)[O-]>>COc1nccc2c([N+](=O)[O-])c(C)ccc12 -US20100069367A1,4,NNc1ccccc1Cl.O=C(CC(=O)C(F)(F)F)c1ccco1>>FC(F)(F)c1cc(-c2ccco2)n(-c2ccccc2Cl)n1 -US20120122842A1,1,CC(C)(C)S(=O)NC1(c2ccc(Br)cc2)COC1.CC(N)=O>>CC(=O)Nc1ccc(C2(NS(=O)C(C)(C)C)COC2)cc1 -US20100197681A1,9,Cc1cc(Cl)nc(Cl)c1.[NH4+]>>Cc1cc(N)nc(Cl)c1 -US04753951,9,N.O=[N+]([O-])c1cnc2cscc2c1Cl>>Nc1c([N+](=O)[O-])cnc2cscc12 -US20110312945A1,1,O=Cc1ccccc1F.O=S([O-])c1ccccc1>>O=Cc1ccccc1S(=O)(=O)c1ccccc1 -US06291507B1,6,CCOC(=O)c1cc2c(n1S(=O)(=O)c1ccc(Cl)c(Cl)c1)CCCC2>>O=C(O)c1cc2c(n1S(=O)(=O)c1ccc(Cl)c(Cl)c1)CCCC2 -US06448269B1,6,CCOC(=O)CC1CCc2cc(NC(=O)c3ccc(NC=NN)cc3)ccc2O1>>NN=CNc1ccc(C(=O)Nc2ccc3c(c2)CCC(CC(=O)O)O3)cc1 -US20140112945A1,2,COc1ccc(C[C@H](N)C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)[C@H]4CCCC[C@H]4C3=O)CC2)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C[C@H](NC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)[C@H]4CCCC[C@H]4C3=O)CC2)cc1OC -US20110213143A1,6,CCOc1ccc2c(c1)CCc1c(CC(CCCNC(=O)OC(C)(C)C)C(=O)O)ncn1-2>>CCOc1ccc2c(c1)CCc1c(CC(CCCN)C(=O)O)ncn1-2 -US20110046109A1,3,CSc1nc(Cl)c(C=O)c(Nc2ccccc2Cl)n1.OB(O)c1ccccc1F>>CSc1nc(Nc2ccccc2Cl)c(C=O)c(-c2ccccc2F)n1 -US20060128691A1,1,Cc1c[nH]cn1.Cc1ccc(F)c(C#N)c1>>Cc1ccc(-n2cnc(C)c2)c(C#N)c1 -US20090023763A1,3,Nc1nc(Br)c(Br)cc1[N+](=O)[O-].OB(O)c1cccc(F)c1>>Nc1nc(-c2cccc(F)c2)c(Br)cc1[N+](=O)[O-] -US09108960B2,1,Cn1nc(C2CCN(c3ccc(N)cc3F)CC2)oc1=O.O=Cc1ccc([N+](=O)[O-])o1>>Cn1nc(C2CCN(c3ccc(/N=C/c4ccc([N+](=O)[O-])o4)cc3F)CC2)oc1=O -US20120232096A1,1,Cc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)(C)C2.Cc1cc(Br)ccc1Cl>>Cc1cc(N2CCN(c3c(C)c(C)c4c(c3C)CC(C)(C)O4)CC2)ccc1Cl -US20140155389A1,1,COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1nc(Cl)cc2cn[nH]c(=O)c12.Oc1cccc(Cl)c1Cl>>COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1nc(Oc2cccc(Cl)c2Cl)cc2cn[nH]c(=O)c12 -US06265434B1,1,BrCc1ccccc1.Oc1c(F)cc(Br)cc1F>>Fc1cc(Br)cc(F)c1OCc1ccccc1 -US20090227560A1,2,CN(CC[C@@H]1CN(C(=O)OCc2ccccc2)CCN1)c1ccccc1.COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)O)c1-c1ccccc1>>COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCN(C(=O)OCc3ccccc3)C[C@H]2CCN(C)c2ccccc2)c1-c1ccccc1 -US20140288111A1,2,C1CCNCC1.COC(=O)c1ccc([N+](=O)[O-])cn1>>O=C(c1ccc([N+](=O)[O-])cn1)N1CCCCC1 -US20140057953A1,3,COc1cccc(N(C)C(=O)c2ccc(Br)s2)c1.OB(O)c1cccc(F)c1>>COc1cccc(N(C)C(=O)c2ccc(-c3cccc(F)c3)s2)c1 -US07855292B2,1,COC(=O)[C@H](OS(C)(=O)=O)[C@H](C)c1ccc(Cl)c(Cl)c1.[N-]=[N+]=[N-]>>COC(=O)[C@@H](N=[N+]=[N-])[C@H](C)c1ccc(Cl)c(Cl)c1 -US05348955,6,O=C(O)[C@@H]1CN(C(=O)OCc2ccccc2)CCN1C(=O)C(c1ccccc1)c1ccccc1>>O=C(O)[C@@H]1CNCCN1C(=O)C(c1ccccc1)c1ccccc1 -US20120157404A1,3,COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C.COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Br)c3ccccc23)[nH]1)C(C)C>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(-c4cnc(C5CCCN5C(=O)C(NC(=O)OC)C(C)C)[nH]4)c4ccccc34)cc2)[nH]1)C(C)C -US20080132477A1,6,C=CCOc1cc(O)cc(C(=O)OC)c1>>C=CCOc1cc(O)cc(C(=O)O)c1 -US20040204408A1,1,CI.Oc1ccccc1-c1nn[nH]n1>>Cn1nnc(-c2ccccc2O)n1 -US04742052,2,O=C(Cl)OCc1ccc([N+](=O)[O-])cc1.O=C(O)CO>>O=C(O)COC(=O)OCc1ccc([N+](=O)[O-])cc1 -US08952004B2,6,CCOC(=O)CC1CCN(c2ncc(Br)cc2[N+](=O)[O-])CC1>>O=C(O)CC1CCN(c2ncc(Br)cc2[N+](=O)[O-])CC1 -US20110144081A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)c(Cl)c1 -US08143274B2,1,CN.O=c1[nH]c(-c2ccccc2C(F)(F)F)cc2ccc(Br)cc12>>CNc1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1 -US06344449B1,7,O=c1[nH]c2ccccc2cc1-c1ccncc1>>O=c1[nH]c2ccccc2cc1C1CCNCC1 -US07312241B2,3,CCOP(=O)(CC#N)OCC.COc1cccc(C(=O)c2ccc(OC)c(OC)c2)c1>>COc1cccc(C(=CC#N)c2ccc(OC)c(OC)c2)c1 -US04005084,7,O=C1COC(COc2ccccc2Cc2cccs2)CN1Cc1ccccc1>>c1ccc(CN2CCOC(COc3ccccc3Cc3cccs3)C2)cc1 -US04252960,2,CC(Oc1ccccc1[N+](=O)[O-])c1nnc(N=C=O)s1.CNCC(OC)OC>>COC(CN(C)C(=O)Nc1nnc(C(C)Oc2ccccc2[N+](=O)[O-])s1)OC -US20140066426A1,1,Cc1c(C(F)(F)F)[nH]c(C(=O)N2CCOCC2)c1-c1ccc(Cl)cc1.Clc1cccc(CBr)c1>>Cc1c(-c2ccc(Cl)cc2)c(C(=O)N2CCOCC2)n(Cc2cccc(Cl)c2)c1C(F)(F)F -US20080306084A1,7,O=C(O)CN(C1CC1)S(=O)(=O)c1c(Cl)cc(Cl)cc1Cl>>O=S(=O)(c1c(Cl)cc(Cl)cc1Cl)N(CCO)C1CC1 -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(CCc2ccccc2)nc1-c1ccccc1>>CCCC(C(=O)O)c1c(C)nc(CCc2ccccc2)nc1-c1ccccc1 -US07727997B2,2,CCCN(CCC)C(=O)c1cc(C(=O)O)cc(-c2noc(C)n2)c1.CCc1cccc(CNC[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)c1>>CCCN(CCC)C(=O)c1cc(C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)CNCc2cccc(CC)c2)cc(-c2noc(C)n2)c1 -US04622397,1,CC(C)c1nnc(Cl)n(C)c1=O.CNC>>CC(C)c1nnc(N(C)C)n(C)c1=O -US06248755B1,1,COc1ccc(COC(=O)[C@@H](C2CCCCC2)N2C[C@H](c3ccccc3)[C@@H](C=O)C2)cc1.Cc1[nH]n(C2CCNCC2)c(=O)c1Cc1ccccc1>>COc1ccc(COC(=O)[C@@H](C2CCCCC2)N2C[C@H](c3ccccc3)[C@@H](CN3CCC(n4[nH]c(C)c(Cc5ccccc5)c4=O)CC3)C2)cc1 -US20100137610A1,1,CN(c1cccc2cc(-c3ncc(CCl)s3)[nH]c12)S(=O)(=O)c1cccs1.O=C1OCC2CNCCN12>>CN(c1cccc2cc(-c3ncc(CN4CCN5C(=O)OCC5C4)s3)[nH]c12)S(=O)(=O)c1cccs1 -US20140249143A1,3,C=CC(=O)OC.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1Br>>COC(=O)/C=C/c1c(N)cc(C(F)(F)F)cc1C(F)(F)F -US07435815B2,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.COc1ccc(N)cn1>>COc1ccc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cn1 -US06376490B1,7,CCOC(=O)c1cn(-c2ccc([N+](=O)[O-])cc2)cn1>>CCOC(=O)c1cn(-c2ccc(N)cc2)cn1 -US07129215B2,10,Cc1ccc(-c2ccccn2)cc1.O=C1CCC(=O)N1Br>>BrCc1ccc(-c2ccccn2)cc1 -US06696476B2,9,COC(=O)CO[C@H]1COc2ccc3cnn(C[C@@H](C)O[Si](C)(C)C(C)(C)C)c3c2C1.N>>C[C@H](Cn1ncc2ccc3c(c21)C[C@@H](OCC(N)=O)CO3)O[Si](C)(C)C(C)(C)C -US05298652,2,CCCCCCCCCCOc1cccc(C(=O)O)c1.COC(=O)CNCC(=O)OC>>CCCCCCCCCCOc1cccc(C(=O)N(CC(=O)OC)CC(=O)OC)c1 -US08329686B2,1,Fc1ccc(CBr)cn1.O=C1Nc2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc2C1=O>>O=C1C(=O)N(Cc2ccc(F)nc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 -US08580973B2,1,FC(F)CCl.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CC(F)F -US20130274257A1,3,Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1I.O=[N+]([O-])c1cccc(B(O)O)c1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cccc([N+](=O)[O-])c1 -US20080300242A1,1,CN1CCNCC1.Cc1c(C=O)cccc1[N+](=O)[O-]>>Cc1c(CN2CCN(C)CC2)cccc1[N+](=O)[O-] -US05852015,7,O=C(O)C1CC(C(=O)O)CN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)C1>>Nc1cccc(S(=O)(=O)N2CC(C(=O)O)CC(C(=O)O)C2)c1 -US07618970B2,7,COC1COCC[C@H]1N[C@@H]1CC[C@@](C(=O)N2CC=C(c3cccc(C(F)(F)F)c3)CC2)(C(C)C)C1>>COC1COCC[C@H]1N[C@@H]1CC[C@@](C(=O)N2CCC(c3cccc(C(F)(F)F)c3)CC2)(C(C)C)C1 -US20040220248A1,7,O=C(Nc1cc([N+](=O)[O-])ccc1F)c1ccccc1>>Nc1ccc(F)c(NC(=O)c2ccccc2)c1 -US08193362B2,9,CC(C)(C)OC(=O)Nc1ccc(C(F)(F)Cl)nc1>>CC(C)(C)OC(=O)Nc1ccc(C(F)F)nc1 -US20140194431A1,6,CC(C)N1CCn2c(Cc3cccc(Cl)c3Cl)nc(=O)c(OCc3ccccc3)c2C1=O>>CC(C)N1CCn2c(Cc3cccc(Cl)c3Cl)nc(=O)c(O)c2C1=O -US20150218124A1,6,COc1cc(C#N)c(Cc2ccc(C(F)(F)F)cc2)c(C#N)c1O>>N#Cc1cc(O)c(O)c(C#N)c1Cc1ccc(C(F)(F)F)cc1 -US08129371B2,1,CC(C)(C)OC(=O)N1CC2CNCC(C1)O2.O=[N+]([O-])c1ccc(-c2nc(Cl)c3cnn(CC(F)(F)F)c3n2)cc1>>CC(C)(C)OC(=O)N1CC2CN(c3nc(-c4ccc([N+](=O)[O-])cc4)nc4c3cnn4CC(F)(F)F)CC(C1)O2 -US04159331,1,CCCc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc(N)cc3)CC2)cc1F.FC(F)(F)c1ccc2c(Cl)ccnc2c1>>CCCc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc(Nc4ccnc5cc(C(F)(F)F)ccc45)cc3)CC2)cc1F -US08637559B2,1,COc1ccc(-c2nc(CCC(=O)c3ccccc3O)co2)cc1OCc1ccccc1.FC(F)Cl>>COc1ccc(-c2nc(CCC(=O)c3ccccc3OC(F)F)co2)cc1OCc1ccccc1 -US08367831B2,6,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3cnccc32)CC1>>O=c1ccc2cnccc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1 -US20150191432A1,2,CCOC(=O)COc1cccc2ccc(OC)nc12.NC[C@@H](O)CN1CCc2ccccc2C1>>COc1ccc2cccc(OCC(=O)NC[C@@H](O)CN3CCc4ccccc4C3)c2n1 -US07517873B2,2,CN1CCC(N)CC1.COCCN1CCC(=O)N(C)c2cnc(Nc3ccc(C(=O)O)cc3OC)nc21>>COCCN1CCC(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc21 -US04013641,2,Nc1ccccc1Oc1c(C(=O)O)[nH]c2ccccc12>>O=C1Nc2ccccc2Oc2c1[nH]c1ccccc21 -US07842713B2,1,COCC1Cc2c(O)cc(C(=O)Nc3ccn(C)n3)cc2O1.O=C(c1ccc(F)cc1)N1CCC1>>COCC1Cc2c(Oc3ccc(C(=O)N4CCC4)cc3)cc(C(=O)Nc3ccn(C)n3)cc2O1 -US08080566B1,1,BrCCCn1c2ccccc2c2ccccc21.CNC>>CN(C)CCCn1c2ccccc2c2ccccc21 -US04889857,1,CNCCC1CNCCO1.O=C(O)c1cn(-c2ccc(F)cc2F)c2c(F)c(F)c(F)cc2c1=O>>CNCCC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4F)c3c2F)CCO1 -US06495699B2,3,Brc1ccncc1.OB(O)c1ccoc1>>c1cc(-c2ccoc2)ccn1 -US20100280067A1,6,COC(=O)c1ccc(OCC2CC2)cc1>>O=C(O)c1ccc(OCC2CC2)cc1 -US20150203515A1,6,COC(=O)C1CC(NCc2ccc3c(C(F)(F)F)c(O[C@H]4CC[C@@H](C(F)(F)F)CC4)ccc3c2)C12CCCCC2>>O=C(O)C1CC(NCc2ccc3c(C(F)(F)F)c(O[C@H]4CC[C@@H](C(F)(F)F)CC4)ccc3c2)C12CCCCC2 -US20130217702A1,2,CC(C)(C)OC(=O)NC1(C(=O)O)CC1.Cc1nc(-c2c(Cl)c3ccccc3n2-c2ccc(CN)cc2)no1>>Cc1nc(-c2c(Cl)c3ccccc3n2-c2ccc(CNC(=O)C3(NC(=O)OC(C)(C)C)CC3)cc2)no1 -US08119663B2,4,Cc1ccc(C(=O)CBr)c(C)n1.NC(=S)C1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1>>Cc1ccc(-c2csc(C3CC(c4ccc(C(F)(F)F)cc4)CN(C(=O)N4CCOCC4)C3)n2)c(C)n1 -US20070167437A1,2,CCOc1nc(C)ncc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCN1CCNCC1>>CCOc1nc(C)ncc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CCS(C)(=O)=O)CC1 -US20080096885A1,1,COC(=O)Cl.Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)NNc1ccccc1>>COC(=O)N(NC(=O)c1c(C)c(-c2ccccc2)nc2ccccc12)c1ccccc1 -US08716296B2,3,COc1ccc(F)cc1B(O)O.O=C(Nc1cc(Cl)ncn1)C1CCN(C(=O)OCc2ccccc2)CC1>>COc1ccc(F)cc1-c1cc(NC(=O)C2CCN(C(=O)OCc3ccccc3)CC2)ncn1 -US20090192192A1,2,CCCCCCCCCCCC(=O)Cl.OCC1CCCCN1>>CCCCCCCCCCCC(=O)OCC1CCCCN1 -US20140094474A1,2,CCOC(=O)c1coc(C(C)(C)O)n1.C[C@@H](CN)n1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1>>C[C@@H](CNC(=O)c1coc(C(C)(C)O)n1)n1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1 -US07560558B2,1,COc1cc2c(Oc3cc(C)c(C)nc3-c3cccc(C)n3)ccnc2cc1O.ClCCBr>>COc1cc2c(Oc3cc(C)c(C)nc3-c3cccc(C)n3)ccnc2cc1OCCCl -US05981546,6,C[C@@H]1C[C@H](CCC2(C)OCCO2)C(=O)N1Cc1ccccc1>>C[C@@H]1C[C@H](CCC2(C)OCCO2)C(=O)N1 -US06933311B2,6,CCOC(=O)Cc1cccc2cnccc12>>O=C(O)Cc1cccc2cnccc12 -US07691874B2,2,O=C(Cl)OCc1ccccc1.Oc1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)NCC3>>O=C(OCc1ccccc1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc13 -US06313137B1,1,Cc1cccc(CCOCc2ccccc2)c1C=O.Cc1nc2c(N)cc(C(N)=O)cn2c1C>>Cc1cccc(CCOCc2ccccc2)c1CNc1cc(C(N)=O)cn2c(C)c(C)nc12 -US04341784,1,CC(=O)CNC1CCNC1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)nc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCC(NCC(C)=O)C3)nc21 -US20150191439A1,1,ClCc1nc(-c2ccccc2)no1.NC12CC3CC(CC(C3)C1)C2>>c1ccc(-c2noc(CNC34CC5CC(CC(C5)C3)C4)n2)cc1 -US07105508B1,9,N#CN.NCc1ccc(N)cc1>>N=C(N)Nc1ccc(CN)cc1 -US05051413,1,CC(C)(C)OC(=O)N1[C@H](C=CCCCBr)COC1(C)C.CC(C)OP(OC(C)C)OC(C)C>>CC(C)OP(=O)(CCCC=C[C@@H]1COC(C)(C)N1C(=O)OC(C)(C)C)OC(C)C -US08962630B2,1,CC(C)(C)[SiH2]OC(C)(C)c1ccc(N)nc1.N#Cc1cc2cnc(Cl)nc2n1C1CCCC1>>CC(C)(C)[SiH2]OC(C)(C)c1ccc(Nc2ncc3cc(C#N)n(C4CCCC4)c3n2)nc1 -US20060264460A1,1,CN(C)c1ccc(C=O)c(Br)c1.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>CN(C)c1ccc(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)c(Br)c1 -US04177278,6,CCOC(=O)C1=C(C)NC(CN2C(=O)c3ccccc3C2=O)=C(C(=O)OCC)C1c1ccccc1Cl>>CCOC(=O)C1=C(C)NC(CN)=C(C(=O)OCC)C1c1ccccc1Cl -US20070135467A1,2,N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)Oc1ccc([N+](=O)[O-])cc1 -US07569601B2,3,O=C(c1ccc(O)cc1)c1ccc(Br)cc1.O=C1C2CCCC1CCC2>>Oc1ccc(C(=C2C3CCCC2CCC3)c2ccc(Br)cc2)cc1 -US07973078B2,7,Cc1c(Cl)cccc1NS(=O)(=O)c1ccc(C(=O)O)cc1>>Cc1c(Cl)cccc1NS(=O)(=O)c1ccc(CO)cc1 -US04806549,1,CCCC(=O)c1cnc2c(OC)cccc2c1Cl.Cc1ccccc1N>>CCCC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C -US20150126522A1,2,Cc1c(OC(C)C)cc(Cl)cc1C(=O)O.Cc1cc(C)c(CN)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(Cl)cc(OC(C)C)c2C)c(=O)[nH]1 -US20130045948A1,2,O=C(Cl)Oc1ccccc1.c1ccc(C2CC(c3csc(C4CCNCC4)n3)=NO2)cc1>>O=C(Oc1ccccc1)N1CCC(c2nc(C3=NOC(c4ccccc4)C3)cs2)CC1 -US20100098634A1,3,CC1(C)OB(c2ccc3scnc3c2)OC1(C)C.Oc1cc(F)cc(Br)c1>>Oc1cc(F)cc(-c2ccc3scnc3c2)c1 -US05547983,6,O=C(OCc1ccccc1)c1ccc2cc(-c3ccc(OC[C@H](O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1>>O=C(O)c1ccc2cc(-c3ccc(OC[C@H](O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 -US20060135524A1,6,O=C(N1C2CCC1CC(C1c3ccccc3Oc3cc(-c4nnn[nH]4)ccc31)C2)C(F)(F)F>>c1ccc2c(c1)Oc1cc(-c3nnn[nH]3)ccc1C2C1CC2CCC(C1)N2 -US20150152108A1,1,CC1(C)CNCCO1.Clc1ccc2c(n1)N[C@H]1CCN2C1>>CC1(C)CN(c2ccc3c(n2)N[C@H]2CCN3C2)CCO1 -US06555584B1,2,CCCCCC(=O)Cl.NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccccc2)c1>>CCCCCC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccccc2)c1 -US04525589,2,O=C(Cl)c1ccccc1.O=S(=O)(c1cccc2cnccc12)N1CCNCC1>>O=C(c1ccccc1)N1CCN(S(=O)(=O)c2cccc3cnccc23)CC1 -US07875728B2,7,O=[N+]([O-])c1ccc2nsnc2c1>>Nc1ccc2nsnc2c1 -US20050065164A1,9,CCOC(=O)C1(C)CN(Cc2ccccc2)CCC1=O>>CC1CN(Cc2ccccc2)CCC1=O -US07229986B2,2,CCCN(CCC)CCc1ccc2c(c1)NCCO2.O=S(=O)(Cl)c1cccc2ccccc12>>CCCN(CCC)CCc1ccc2c(c1)N(S(=O)(=O)c1cccc3ccccc13)CCO2 -US05760032,6,CCOC(=O)CCc1nnc(CNC(=O)c2ccc(Cl)c(Cl)c2)n1-c1sc(CC)cc1C(=O)c1ccccc1Cl>>CCc1cc(C(=O)c2ccccc2Cl)c(-n2c(CCC(=O)O)nnc2CNC(=O)c2ccc(Cl)c(Cl)c2)s1 -US20140296306A1,7,CC(C)(C)CC1C=C(C(=O)O)C1>>CC(C)(C)CC1CC(C(=O)O)C1 -US06521643B1,7,COc1ccnc(-c2ccc(C)c([N+](=O)[O-])c2)c1>>COc1ccnc(-c2ccc(C)c(N)c2)c1 -US07473786B1,4,C#Cc1ccccc1.Nc1c(Cl)cc(Cl)cc1I>>Clc1cc(Cl)c2[nH]c(-c3ccccc3)cc2c1 -US06252086B1,3,O=C1Cc2c(I)cccc2N1.O=Cc1ccc[nH]1>>O=C1Nc2cccc(I)c2/C1=C/c1ccc[nH]1 -US05969146,2,CCOC(=O)Cl.COC(=O)c1sc2cc(OC)ccc2c1N>>CCOC(=O)Nc1c(C(=O)OC)sc2cc(OC)ccc12 -US20020156311A1,1,Cc1c(N)cccc1[N+](=O)[O-].O=Cc1ccc2c(c1)OCCO2>>Cc1c(NCc2ccc3c(c2)OCCO3)cccc1[N+](=O)[O-] -US06780861B2,2,N[C@H]1CN2CCC1CC2.O=C(Cl)OCc1ccccc1>>O=C(N[C@H]1CN2CCC1CC2)OCc1ccccc1 -US08546427B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.Cc1ccc2c(c1)C(C)(C)CC(c1cccc(N)c1)N2>>Cc1ccc(S(=O)(=O)Nc2cccc(C3CC(C)(C)c4cc(C)ccc4N3)c2)cc1 -US07560558B2,6,COC(=O)CCCCCCC(=O)c1cc(C)ccc1OC>>COC(=O)CCCCCCC(=O)c1cc(C)ccc1O -US05710171,1,COC(=O)c1cccc(I)c1.O=[N+]([O-])c1cccc(O)c1>>COC(=O)c1cccc(Oc2cccc([N+](=O)[O-])c2)c1 -US20140296225A1,3,Brc1ccc2nonc2c1.C=CC[Sn](CCCC)(CCCC)CCCC>>C=CCc1ccc2nonc2c1 -US05916983,7,CCCCC=CCCCCOC(C)=O>>CCCCC=CCCCCO -US20100029621A1,2,Nc1ccc(C(=O)O)cc1OC(F)(F)F.OC(c1ccc(CN2CCNCC2)cc1)(C(F)(F)F)C(F)(F)F>>Nc1ccc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1OC(F)(F)F -US20100234378A1,4,C#CCNC(=O)OC(C)(C)C.C[Si](C)(C)N=[N+]=[N-]>>CC(C)(C)OC(=O)NCc1cnn[nH]1 -US20150148340A1,7,CC(=O)Nc1ccc(NC2CCC2)c([N+](=O)[O-])c1>>CC(=O)Nc1ccc(NC2CCC2)c(N)c1 -US07229987B2,1,C1CCNCC1.O=S(=O)(CCCl)Nc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1>>O=S(=O)(CCN1CCCCC1)Nc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1 -US05302617,7,O=C1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2CC2OCCO2)O1>>OC1CC2C(CC(OC3CCCCO3)C2CC2OCCO2)O1 -US20140107097A1,3,CON(C)C(=O)c1csc(C)n1.Cn1cncc1Br>>Cc1nc(C(=O)c2cncn2C)cs1 -US04665215,6,CC(=O)Oc1ccc(C(=O)O)cc1>>O=C(O)c1ccc(O)cc1 -US08048909B2,6,COC(=O)c1ccccc1S(=O)(=O)n1cc(CN(C)C(=O)OC(C)(C)C)cc1-c1ccccc1>>CN(Cc1cc(-c2ccccc2)n(S(=O)(=O)c2ccccc2C(=O)O)c1)C(=O)OC(C)(C)C -US20150210697A1,1,CC(C)(C)OC(=O)N1CCN(c2cc(C#N)cc(N)c2Cl)C(=O)C1.COc1ccc(CN(c2nc(Cl)nn3c(C#N)cnc23)C2CC2)cc1>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCN(C(=O)OC(C)(C)C)CC4=O)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1 -US06159979,7,CC(=O)N1CCc2ccc([N+](=O)[O-])cc21>>CC(=O)N1CCc2ccc(N)cc21 -US04405628,3,Cc1c[nH]c(=O)[nH]1.O=C(Cl)c1ccncc1>>Cc1[nH]c(=O)[nH]c1C(=O)c1ccncc1 -US04051148,7,COC(=O)c1ccc(C(=O)O)cc1SCc1ccccc1>>COC(=O)c1ccc(CO)cc1SCc1ccccc1 -US05633371,6,COc1cc(C(=O)C(C)C)cc([N+](=O)[O-])c1O>>CC(C)C(=O)c1cc(O)c(O)c([N+](=O)[O-])c1 -US08586550B2,2,CC(C)(C)OC(=O)NCC(=O)O.CNOC>>CON(C)C(=O)CNC(=O)OC(C)(C)C -US20100227870A1,9,NO.O=Cc1c(F)ccc(Cl)c1C(F)(F)F>>ON=Cc1c(F)ccc(Cl)c1C(F)(F)F -US05859014,1,C[Si](C)(C)CCOCn1cc(F)c(=O)n(CCCCl)c1=O.Fc1ccc(N2CCNCC2)c(OCC(F)(F)F)c1>>C[Si](C)(C)CCOCn1cc(F)c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O -US20120270865A2,7,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc([N+](=O)[O-])cc3c2C)C2CCCCC2)cc1>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(N)cc3c2C)C2CCCCC2)cc1 -US20120059001A1,9,CC(c1oc2ccc(Br)cc2c(=O)c1-c1ccccc1)n1cnc2c(N)ncnc21>>CC(c1oc2ccccc2c(=O)c1-c1ccccc1)n1cnc2c(N)ncnc21 -US09051296B2,6,CC(C)(C)OC(=O)NCCn1ccc2cc(C(=O)N3CCC(Oc4ccc(Cl)cc4)CC3)ccc21>>NCCn1ccc2cc(C(=O)N3CCC(Oc4ccc(Cl)cc4)CC3)ccc21 -US20140274688A1,3,CC1(C)OB(c2ccc(CNC(=O)OCc3ccccc3)cc2)OC1(C)C.FC(F)(F)Oc1ccc(-n2cnc(Br)n2)cc1>>O=C(NCc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1)OCc1ccccc1 -US20100190747A1,1,CC(C)CCO.O=[N+]([O-])c1ccc(F)cc1>>CC(C)CCOc1ccc([N+](=O)[O-])cc1 -US20150183763A1,3,C[C@@H](OCc1cc(F)cc(B2OC(C)(C)C(C)(C)O2)c1)C(F)(F)F.Nc1cc(I)n(-c2ccc(Cl)cc2)n1>>C[C@@H](OCc1cc(F)cc(-c2cc(N)nn2-c2ccc(Cl)cc2)c1)C(F)(F)F -US06077812,9,Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c([N+](=O)[O-])c2F)c1=O.[NH4+]>>Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c([N+](=O)[O-])c2N)c1=O -US20150266862A1,7,COC(=O)c1cccc(S(=O)CC(C)C)c1>>CC(C)CS(=O)c1cccc(CO)c1 -US20120142686A1,1,CNC(=O)c1c2cc(C3CC3)c(NS(C)(=O)=O)cc2nn1-c1ccc(Br)cc1.Oc1ccc(F)cc1>>CNC(=O)c1c2cc(C3CC3)c(NS(C)(=O)=O)cc2nn1-c1ccc(Oc2ccc(F)cc2)cc1 -US04103015,9,NC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O>>N#Cc1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O -US04742061,6,COC(=O)C1CCC(=O)N1Cc1ccccc1C(F)(F)F>>O=C(O)C1CCC(=O)N1Cc1ccccc1C(F)(F)F -US20040014802A1,3,CCCC(=O)Nc1nn(COCC[Si](C)(C)C)c2cc(Cl)ccc12.Cc1ccc(B(O)O)cc1>>CCCC(=O)Nc1nn(COCC[Si](C)(C)C)c2cc(-c3ccc(C)cc3)ccc12 -US08822430B2,6,CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1>>CC1(C)OB(c2ccc(-c3cnc([C@@H]4CCCN4)[nH]3)cc2)OC1(C)C -US20100210592A1,1,CC(C)(C)OC(=O)NC(C(=O)c1ccc(O)cc1)c1ccc(Cl)c(Cl)c1.CC(C)CO>>CC(C)COc1ccc(C(=O)C(NC(=O)OC(C)(C)C)c2ccc(Cl)c(Cl)c2)cc1 -US07253285B2,1,CC[S-].Clc1ccnc2ccc(Br)cc12>>CCSc1ccnc2ccc(Br)cc12 -US08835451B2,4,NC(=S)Nc1cccc(F)c1.O=C(CBr)c1ccc(Br)cc1>>Fc1cccc(Nc2nc(-c3ccc(Br)cc3)cs2)c1 -US05883092,2,CC(C)c1ccccc1N.COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(N2CCN(C=O)CC2)nc1OCCC(=O)O>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(N2CCN(C=O)CC2)nc1OCCC(=O)Nc1ccccc1C(C)C -US20030220198A1,7,CC(=O)Nc1ccc([N+](=O)[O-])cc1>>CC(=O)Nc1ccc(N)cc1 -US20150118186A1,7,O=[N+]([O-])c1cnc(-c2cnn3ccncc23)nc1NC1CCOCC1>>Nc1cnc(-c2cnn3ccncc23)nc1NC1CCOCC1 -US20110245241A1,2,CC1(C)OCCn2c1nc(C(=O)NN)c(OCc1ccccc1)c2=O.O=C(Cl)Cc1ccc(F)cc1>>CC1(C)OCCn2c1nc(C(=O)NNC(=O)Cc1ccc(F)cc1)c(OCc1ccccc1)c2=O -US20080261921A1,1,CC(C)(C)OC(=O)NC(C(=O)O)c1cccc(Br)c1.CI>>CN(C(=O)OC(C)(C)C)C(C(=O)O)c1cccc(Br)c1 -US20060160870A1,6,COC(=O)[C@H](Cc1ccc(N(CCN(C)C(=O)C2CCCCC2)S(C)(=O)=O)cc1)NC1=NS(=O)(=O)c2ccccc21>>CN(CCN(c1ccc(C[C@H](NC2=NS(=O)(=O)c3ccccc32)C(=O)O)cc1)S(C)(=O)=O)C(=O)C1CCCCC1 -US20080146562A1,1,Nc1cccnc1.O=[N+]([O-])c1ccc(-c2nc(Cl)c3ccc(F)cc3n2)o1>>O=[N+]([O-])c1ccc(-c2nc(Nc3cccnc3)c3ccc(F)cc3n2)o1 -US04675403,2,NCCCCO.O=C(NC1(C(=O)O)CCCC1)OCc1ccccc1>>O=C(NC1(C(=O)NCCCCO)CCCC1)OCc1ccccc1 -US05639782,5,COc1cc(C=O)cc(I)c1OC.OCCCO>>COc1cc(C2OCCCO2)cc(I)c1OC -US05665718,1,CCCNCCC.O=C1c2c(Br)cccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCCN12>>CCCN(CCC)Cc1nc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2c(Br)cccc2-3)no1 -US06331637B1,2,Cc1cc(N)on1.O=S(=O)(Cl)c1ccc(Br)s1>>Cc1cc(NS(=O)(=O)c2ccc(Br)s2)on1 -US08901141B2,1,CCOC(=O)CCCn1c(Cl)nc2c(Cl)ccc(C(CC)CC)c21.COc1cc(Cl)cc(C)c1N>>CCOC(=O)CCCn1c(Nc2c(C)cc(Cl)cc2OC)nc2c(Cl)ccc(C(CC)CC)c21 -US20120289474A1,3,CCn1nnc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(Br)cc32)n1.OB(O)c1ccc(F)cc1>>CCn1nnc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccc(F)cc4)cc32)n1 -US20130096113A1,1,Brc1nc2ccc(Cn3cnc4ccccc43)cc2s1.N[C@@H]1CCCC[C@H]1O>>O[C@@H]1CCCC[C@H]1Nc1nc2ccc(Cn3cnc4ccccc43)cc2s1 -US04598152,6,Fc1ccc2c(CCCN3CCC4(CC3)OCCO4)noc2c1>>O=C1CCN(CCCc2noc3cc(F)ccc23)CC1 -US07595327B2,2,CC[C@]1(C(=O)OC)CCC[C@H]1N.Cc1cc(COc2ccc(S(=O)(=O)Cl)cc2)c2ccccc2n1>>CC[C@]1(C(=O)OC)CCC[C@H]1NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 -US20040034089A1,6,CCc1c[nH]c(C2Cc3ccccc3N2C(C)=O)n1>>CCc1c[nH]c(C2Cc3ccccc3N2)n1 -US20150152095A1,7,COc1ccccc1C1=NCCC1>>COc1ccccc1C1CCCN1 -US20140179667A1,6,COC(=O)c1cc(OC(C)C)cc2c1CCNC2=O>>CC(C)Oc1cc(C(=O)O)c2c(c1)C(=O)NCC2 -US04350817,6,CCOC(=O)c1c(N)c2cccnc2n(CC)c1=O>>CCn1c(=O)c(C(=O)O)c(N)c2cccnc21 -US08981084B2,2,O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1.c1cncc(N2CCNCC2)c1>>O=C(c1cccc(-c2noc(C(F)(F)F)n2)c1)N1CCN(c2cccnc2)CC1 -US20100048549A1,2,CC(C)(C)OC(=O)N1CCC(C(N)COCc2ccccc2)CC1.Cc1ccc(S(=O)(=O)Cl)c2ccccc12>>Cc1ccc(S(=O)(=O)NC(COCc2ccccc2)C2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc12 -US06531600B1,1,C1CCNCC1.CCCCn1c(=O)c2[nH]c(Br)nc2n(CCCC)c1=O>>CCCCn1c(=O)c2[nH]c(N3CCCCC3)nc2n(CCCC)c1=O -US07423030B2,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.O=Cc1ccc2ccccc2c1>>CC(C)(C)OC(=O)N[C@@H]1CCN(Cc2ccc3ccccc3c2)C1 -US20060148811A1,7,O=C(CN1CCN(Cc2ccccc2)CC1)c1ccc([N+](=O)[O-])cc1>>Nc1ccc(C(=O)CN2CCN(Cc3ccccc3)CC2)cc1 -US07064124B2,2,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.NC1CCCCC1>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)NC3CCCCC3)c2)=C(C)C1=O -US20150225452A1,1,C=O.COC(=O)c1ccc(CNc2ccc(C[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N3Cc4ccccc4C[C@H]3C(=O)N[C@@H]3CCCc4ccccc43)cc2)cc1>>COC(=O)c1ccc(CN(C)c2ccc(C[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N3Cc4ccccc4C[C@H]3C(=O)N[C@@H]3CCCc4ccccc43)cc2)cc1 -US20090221555A1,1,COCCBr.O=C1CCCc2ccc([N+](=O)[O-])cc2N1>>COCCN1C(=O)CCCc2ccc([N+](=O)[O-])cc21 -US20130338142A1,1,O=[N+]([O-])c1ccc(F)cc1.OC[C@@H]1COCCN1>>O=[N+]([O-])c1ccc(N2CCOC[C@H]2CO)cc1 -US06610692B1,7,CCOC(=O)C(F)(F)c1ccccn1>>OCC(F)(F)c1ccccn1 -US20070270587A1,6,CC1CCN2C(=N1)C1(OCCCO1)c1cc(S(=O)(=O)N3CCCC3)ccc12>>CC1CCN2C(=N1)C(=O)c1cc(S(=O)(=O)N3CCCC3)ccc12 -US20130102617A1,2,C=CCOC(=O)Cl.COC(=O)c1cnc(N)cn1>>C=CCOC(=O)Nc1cnc(C(=O)OC)cn1 -US05216148,2,CCOC(=O)c1ccc(C(=O)Cl)cc1.CN1C(=O)CCCc2cc(N)ccc21>>CCOC(=O)c1ccc(C(=O)Nc2ccc3c(c2)CCCC(=O)N3C)cc1 -US20150224113A1,9,COCCCNC(=O)c1ccc(Cl)nc1.NN>>COCCCNC(=O)c1ccc(NN)nc1 -US20150057260A1,9,CCOC(=O)c1nc(Cl)ncc1NCC1(C)COC1.N>>CC1(CNc2cnc(Cl)nc2C(N)=O)COC1 -US20040018192A1,1,O=S(=O)(NCCBr)c1ccc(S(=O)(=O)Nc2cccc3c(Cl)c[nH]c23)cc1.c1c[nH]cn1>>O=S(=O)(NCCn1ccnc1)c1ccc(S(=O)(=O)Nc2cccc3c(Cl)c[nH]c23)cc1 -US20080090774A1,1,N[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O.Nc1ncnc(Cl)c1[N+](=O)[O-]>>Nc1ncnc(N[C@@H]2C[C@H](CO)[C@@H](O)[C@H]2O)c1[N+](=O)[O-] -US05578627,1,Cc1ncc(C(CO)NC(c2ccccc2)(c2ccccc2)c2ccccc2)s1.Clc1ccc2onc(Cl)c2c1>>Cc1ncc(C(COc2noc3ccc(Cl)cc23)NC(c2ccccc2)(c2ccccc2)c2ccccc2)s1 -US20150183801A1,1,O=C(Nc1ccc(OC(F)(F)C(F)F)cc1)c1cnc(Cl)c(Br)c1.O[C@@H]1CCNC1>>O=C(Nc1ccc(OC(F)(F)C(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1 -US04459150,2,CC(=O)Cl.Cc1ccc(-n2ncc(C#N)c2N)c(Cl)c1>>CC(=O)Nc1c(C#N)cnn1-c1ccc(C)cc1Cl -US06294549B1,6,COC(=O)CCCc1csc(N)n1>>Nc1nc(CCCC(=O)O)cs1 -US07863332B2,1,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1.ClCCCI>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCCCCl)c1 -US20130059853A1,1,CC(C)CBr.COc1ccc(-c2cccc3c2CCC3=O)c(O)c1OCC1CC1>>COc1ccc(-c2cccc3c2CCC3=O)c(OCC(C)C)c1OCC1CC1 -US20050148627A1,6,CCc1cc2c(c(Cl)c1OC)OC(C(F)(F)F)C(C(=O)OC)=C2>>CCc1cc2c(c(Cl)c1OC)OC(C(F)(F)F)C(C(=O)O)=C2 -US07964591B2,2,CC(C)CCNC(=O)c1ccc(N2CCNCC2)nn1.O=C(Cl)c1ccccc1[N+](=O)[O-]>>CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3[N+](=O)[O-])CC2)nn1 -US05707991,6,COC(=O)c1cccc(NC(=O)NCC(=O)N2C(C(=O)OC(C)(C)C)CC(C(C)=O)C2c2ccccc2)c1>>CC(=O)C1CC(C(=O)OC(C)(C)C)N(C(=O)CNC(=O)Nc2cccc(C(=O)O)c2)C1c1ccccc1 -US05607956,3,CC(C)[Mg+].CON(C)C(=O)c1oc(C)nc1C>>Cc1nc(C)c(C(=O)C(C)C)o1 -US20110124636A1,2,CC(C)(C)OC(=O)N1[C@H](CN)C[C@@H]2C[C@@H]21.O=C(O)c1cccc2c1OCCO2>>CC(C)(C)OC(=O)N1[C@H](CNC(=O)c2cccc3c2OCCO3)C[C@@H]2C[C@@H]21 -US20080255083A1,1,ClCc1cccnn1.O=c1cc(O)ccn1CCc1ccc(CO)cc1>>O=c1cc(OCc2cccnn2)ccn1CCc1ccc(CO)cc1 -US20040067960A1,2,CC(=O)Cl.CC1(C)CCNc2c(CCN3CCN(c4nsc5ccccc45)CC3)cccc21>>CC(=O)N1CCC(C)(C)c2cccc(CCN3CCN(c4nsc5ccccc45)CC3)c21 -US07687515B2,3,COc1ccc(B(O)O)cc1C(F)(F)F.N#Cc1nc(Cl)cc(N)c1[N+](=O)[O-]>>COc1ccc(-c2cc(N)c([N+](=O)[O-])c(C#N)n2)cc1C(F)(F)F -US20130245084A1,1,COC(=O)c1ccc([C@@H]2CCC(=O)C2)cc1.COc1cc([C@@H](C)N)ccc1F>>COC(=O)c1ccc([C@@H]2CC[C@H](N[C@H](C)c3ccc(F)c(OC)c3)C2)cc1 -US20130296312A1,3,CN(Cc1cccc(B(O)O)c1)S(C)(=O)=O.Clc1nc2c(Br)cccn2n1>>CN(Cc1cccc(-c2cccn3nc(Cl)nc23)c1)S(C)(=O)=O -US07745641B2,2,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.O=S(=O)(Cl)c1cccc(Cl)c1>>CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3cccc(Cl)c3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21 -US20060009461A1,1,O=C(CCl)Nc1cccc(Cl)c1Cl.c1ccc(N2CCNCC2)nc1>>O=C(CN1CCN(c2ccccn2)CC1)Nc1cccc(Cl)c1Cl -US20070015783A1,2,O=C1C(Cc2ccccc2)NC2(CCNCC2)N1Cc1ccccc1.S=C=Nc1ccccc1>>O=C1C(Cc2ccccc2)NC2(CCN(C(=S)Nc3ccccc3)CC2)N1Cc1ccccc1 -US20090118305A1,6,CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc(N)c(-c4nc5ccccc5o4)c3)nn2)CC1>>Nc1ncc(-c2cn(C3CCNCC3)nn2)cc1-c1nc2ccccc2o1 -US20040192708A1,2,CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(N)cc3)nc21.Cc1ccc(C)c(S(=O)(=O)Cl)c1>>CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(NS(=O)(=O)c4cc(C)ccc4C)cc3)nc21 -US20060094767A1,1,CC1(C)C(=O)Nc2ccc(COC(=O)N3CCN(C[C@@]4(C)Cn5cc([N+](=O)[O-])nc5O4)CC3)cc21.CI>>CN1C(=O)C(C)(C)c2cc(COC(=O)N3CCN(C[C@@]4(C)Cn5cc([N+](=O)[O-])nc5O4)CC3)ccc21 -US06242471B1,4,CCOC(=O)c1oc(SC)c2c1CCC(Br)C2=O.NC(=S)c1ccccc1>>CCOC(=O)c1oc(SC)c2c1CCc1sc(-c3ccccc3)nc1-2 -US20140213586A1,1,COc1cncc(N)c1.O=Cc1ccccc1>>COc1cncc(N=Cc2ccccc2)c1 -US20090023725A1,3,Cc1c(F)cc(C(=O)NC2CC2)cc1B(O)O.Oc1ccc(-c2noc3cc(Br)ccc23)cc1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(-c3ccc(O)cc3)noc2c1 -US05648368,9,CC(C)(C)OC(=O)N1CCC(CCI)CC1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC(CCN=[N+]=[N-])CC1 -US20100266538A1,9,Clc1ccc2ncc(Cl)nc2c1.N>>Nc1cnc2ccc(Cl)cc2n1 -US05430062,7,COc1ccc(C(=O)c2cc(OC)c(OC)c(OC)c2)cc1>>COc1ccc(C(O)c2cc(OC)c(OC)c(OC)c2)cc1 -US05654316,1,O=CCC(CC(=O)n1ccc2ccccc21)c1ccc(Cl)c(Cl)c1.OC1(c2ccccc2)CCNCC1>>O=C(CC(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1)n1ccc2ccccc21 -US20130040933A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1ccc(S(=O)(=O)n2cc(Br)c3cc(Cl)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(Cl)cnc32)cc1 -US20110086860A1,3,C[Mg+].O=Cc1cc(/C=C/C(=O)NC2CCc3ccccc32)ccc1-n1ccnc1>>CC(O)c1cc(/C=C/C(=O)NC2CCc3ccccc32)ccc1-n1ccnc1 -US20120252842A1,1,CCOC(=O)CCCBr.COc1cc2c(cc1O)C(=O)CC2>>CCOC(=O)CCCOc1cc2c(cc1OC)CCC2=O -US20130217664A1,1,CCc1cc(OCC#N)ccc1Nc1cc2c(cn1)ncn2C.CI>>CCc1cc(OCC#N)ccc1N(C)c1cc2c(cn1)ncn2C -US20030176454A1,1,Cc1ncn(-c2cccc(N)c2)c1C.Clc1ncnc2c(-c3cccs3)cccc12>>Cc1ncn(-c2cccc(Nc3ncnc4c(-c5cccs5)cccc34)c2)c1C -US20110212956A1,2,CC(=O)OC(C)=O.COc1cccc(CCN)c1>>COc1cccc(CCNC(C)=O)c1 -US08183262B2,3,Cc1cc(-c2cc(C(F)(F)F)nc(Cl)n2)ccc1C(F)(F)F.OB(O)c1cccc(Br)c1>>Cc1cc(-c2cc(C(F)(F)F)nc(-c3cccc(Br)c3)n2)ccc1C(F)(F)F -US08598357B2,2,CC(C)C(=O)O.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1>>CC(C)C(=O)N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1 -US20110092461A1,2,Cc1cc(C(=O)N(C)C)ccc1C(=O)O.Nc1ccc(Cl)c(-c2ccccn2)c1>>Cc1cc(C(=O)N(C)C)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1 -US20120252818A1,6,CC(=O)Nc1cccc(Sc2cnc(N3CCN(C)CC3)nc2OCc2cccnc2)c1>>CN1CCN(c2ncc(Sc3cccc(N)c3)c(OCc3cccnc3)n2)CC1 -US20070197512A1,1,Cc1cc(C)c(O)c(NC(=O)[C@@H](Cl)CC(C)C)c1>>Cc1cc(C)c2c(c1)NC(=O)[C@@H](CC(C)C)O2 -US04994455,1,CCOC(=O)CCCBr.c1cnc(N2CCNCC2)nc1>>CCOC(=O)CCCN1CCN(c2ncccn2)CC1 -US20080300266A1,3,C#CC.Clc1ccc(CNC2CCN(c3ccc(I)cn3)C2)c(Cl)c1>>CC#Cc1ccc(N2CC[C@H](NCc3ccc(Cl)cc3Cl)C2)nc1 -US20100063038A1,1,C1COCCN1.Nc1ncnn2c(CCCBr)cc(Br)c12>>Nc1ncnn2c(CCCN3CCOCC3)cc(Br)c12 -US20130345123A1,1,CC(C)(C)OC(=O)N[C@H]1CCS[C@H]2CCC[C@@H](CO)N2C1=O.CI>>COC[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)OC(C)(C)C)C(=O)N21 -US20030125317A1,6,COC(=O)CC(Cc1ccc(OC)cc1CN(CC(F)(F)F)C(=O)OC(C)(C)C)C(=O)OC>>COC(=O)CC(Cc1ccc(OC)cc1CNCC(F)(F)F)C(=O)OC -US20140058098A1,2,CC(=O)OC(C)=O.CC(C)n1ncnc1-c1cc2n(n1)-c1cc(C3CNC3)ccc1OCC2>>CC(=O)N1CC(c2ccc3c(c2)-n2nc(-c4ncnn4C(C)C)cc2CCO3)C1 -US04062869,2,Cc1cccc(O)c1.O=C(Cl)C(=O)c1c[nH]c2ccccc12>>Cc1cccc(OC(=O)C(=O)c2c[nH]c3ccccc23)c1 -US20080299076A1,2,CC(=O)OC(C)=O.CCOc1ccccc1-n1c(C(C)N2CCNCC2)nc2ccccc2c1=O>>CCOc1ccccc1-n1c(C(C)N2CCN(C(C)=O)CC2)nc2ccccc2c1=O -US20120207763A1,1,O=[N+]([O-])c1ccc(O)cc1.OCCN1CCCC1>>O=[N+]([O-])c1ccc(OCCN2CCCC2)cc1 -US06329396B1,6,COc1ccc(C(C)(C)C#CC(F)(F)F)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1>>COc1ccc(C(C)(C)C#CC(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 -US20120065195A1,3,CC1(C)Cc2ccc(Br)cc2C2(C1)N=C(N)N(CC(F)(F)F)C2=O.OB(O)c1cncnc1>>CC1(C)Cc2ccc(-c3cncnc3)cc2C2(C1)N=C(N)N(CC(F)(F)F)C2=O -US20140088117A1,9,Cn1ncc([N+](=O)[O-])c1C1CCC(CI)O1.[N-]=[N+]=[N-]>>Cn1ncc([N+](=O)[O-])c1C1CCC(CN=[N+]=[N-])O1 -US07442701B2,3,CC(C)(C)c1ccc(B(O)O)cc1.O=c1cc(Cl)cn[nH]1>>CC(C)(C)c1ccc(-c2cn[nH]c(=O)c2)cc1 -US20110257151A1,6,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(C(=O)Nc3ccccc3)c1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(C(=O)Nc2ccccc2)c1 -US20150057260A1,9,COC(=O)c1nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)cc(-c2ccnn2C)n1.N>>CN1CC[C@@](O)(C#Cc2cccc(-c3cc(-c4ccnn4C)nc(C(N)=O)n3)c2)C1=O -US20130252890A1,1,CNCCCCS(=O)(=O)CCCC(F)(F)C(F)(F)F.Oc1ccc2c(c1)CCCC(c1ccc(F)c(F)c1)=C2CCCCCCBr>>CN(CCCCCCC1=C(c2ccc(F)c(F)c2)CCCc2cc(O)ccc21)CCCCS(=O)(=O)CCCC(F)(F)C(F)(F)F -US05747537,3,CCCCC/C=C/C=O.O=C(O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCC=CC=CCCCCC(=O)O -US07629353B2,1,Cn1cncc1CO.O=C1OC2(CCN(C(=O)c3c[nH]c4cc(Cl)ccc34)CC2)c2ccc(F)cc21>>Cn1cncc1Cn1cc(C(=O)N2CCC3(CC2)OC(=O)c2cc(F)ccc23)c2ccc(Cl)cc21 -US05563142,1,C1CNCCN1.CC(C)Nc1c(Cl)cnnc1Cl>>CC(C)Nc1c(Cl)cnnc1N1CCNCC1 -US20130296327A1,1,CN(C)C(=O)C(Cc1cccc(O)c1)NC(=O)OC(C)(C)C.N#Cc1cccc(B(O)O)c1>>CN(C)C(=O)C(Cc1cccc(Oc2cccc(C#N)c2)c1)NC(=O)OC(C)(C)C -US20120238575A1,3,COc1ccccc1B(O)O.Clc1cc(Cl)ncn1>>COc1ccccc1-c1cc(Cl)ncn1 -US20090215778A1,1,COc1ccc(-c2nc3c(C(=O)N4CCNC[C@H]4C)cnn3c(C(F)(F)F)c2C)cc1.C[C@@H](O)c1ccccn1>>COc1ccc(-c2nc3c(C(=O)N4CCN([C@@H](C)c5ccccn5)C[C@H]4C)cnn3c(C(F)(F)F)c2C)cc1 -US05331006,6,COC(=O)[C@](C)(CC1CN=C(c2ccccc2)c2ccccc2N1C)NC(=O)OC1C2CC3CC(C2)CC1C3>>CN1c2ccccc2C(c2ccccc2)=NCC1C[C@](C)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)O -US20050277611A1,1,CCCCCCCCCCCCCCOC[C@@H](CBr)OCCCCCCCCCCCCCC.CNC>>CCCCCCCCCCCCCCOC[C@@H](CN(C)C)OCCCCCCCCCCCCCC -US20130029991A1,2,CC(C)(C)OC(=O)N1CCC(CNC(=O)CN)CC1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2-c2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC(CNC(=O)CNC(=O)c2ccc(S(=O)(=O)Nc3ccccc3-c3ccccc3)cc2)CC1 -US20040186099A1,4,CC(=O)CCC(C)=O.NCCO>>Cc1ccc(C)n1CCO -US06432950B1,1,Cc1sc2nc(Cl)nc(NCCc3ccc4c(c3)OCO4)c2c1C.c1cn[nH]c1>>Cc1sc2nc(-n3cccn3)nc(NCCc3ccc4c(c3)OCO4)c2c1C -US20120108583A1,2,COC(=O)c1cc2nc(Nc3c(C)cccc3Cl)[nH]c2c2c1OC(C)(C)C2.Nc1cc(F)c(F)cc1F>>Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3cc(F)c(F)cc3F)c3c(c2[nH]1)CC(C)(C)O3 -US06743924B2,1,Cc1ccc(S(=O)(=O)NN)cc1.O=CC(Cl)Cl>>Cc1ccc(S(=O)(=O)NN=CC(Cl)Cl)cc1 -US04495187,6,CCc1nnc2c(OC)nc3cc(OC)ccc3n12>>CCc1nnc2c(O)nc3cc(OC)ccc3n12 -US20100210642A1,3,C#C[Si](C)(C)C.FC(F)(F)c1ccc(-c2cc(C(F)(F)F)n3ncc(I)c3n2)cc1>>C[Si](C)(C)C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12 -US07115640B2,5,CSc1nc2cc(N)ccc2s1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CSc1nc2cc(NC(=O)C(F)(F)F)ccc2s1 -US06100272,1,CCCBr.Cc1cc(N2CCCC2=O)ccc1-c1ccc(C(=O)N2CCc3cc4c(cc32)C2(CCNCC2)CO4)cc1>>CCCN1CCC2(CC1)COc1cc3c(cc12)N(C(=O)c1ccc(-c2ccc(N4CCCC4=O)cc2C)cc1)CC3 -US20030219832A1,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ncc(C)s2)=CCC3(C)C)cc1>>Cc1cnc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)s1 -US20130040930A1,2,CS(=O)(=O)NCc1ccc(C(=O)O)cc1.Cc1cc(C2CC2)cnc1N1CCNCC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(CNS(C)(=O)=O)cc2)CC1 -US20110065724A1,9,COC(=O)c1c(-c2ccc(Cl)cc2)sc(Br)c1NC(=O)OCc1ccccc1>>COC(=O)c1c(NC(=O)OCc2ccccc2)csc1-c1ccc(Cl)cc1 -US20100305133A1,1,COC(=O)c1c(OC)ccc2nc(Cl)cnc12.Nc1ccccc1>>COC(=O)c1c(OC)ccc2nc(Nc3ccccc3)cnc12 -US08283363B2,6,CC(C)(C)OC(=O)N(Cc1ccccc1)NC(=O)C(=O)C(Cc1ccccc1)NC(=O)[C@H]1CCC(=O)N1Cc1ccccc1>>O=C(NNCc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)[C@H]1CCC(=O)N1Cc1ccccc1 -US07687435B2,2,CCOC(=O)C(N)C(=O)c1ccccc1C.O=C(Cl)c1ccc(F)cc1C(F)(F)F>>CCOC(=O)C(NC(=O)c1ccc(F)cc1C(F)(F)F)C(=O)c1ccccc1C -US20020193367A1,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1.CCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl>>CCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3nncc3COC3CCCCO3)c2)cc1Cl -US07943634B2,10,COC(=O)c1ccc(OC2CCCC2)c2oc(C)cc12.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(OC2CCCC2)c2oc(CBr)cc12 -US08039493B2,3,CC(C)CN(Cc1cncc(Br)c1)S(=O)(=O)c1ccccc1Cl.CS(=O)(=O)c1cccc(B(O)O)c1>>CC(C)CN(Cc1cncc(-c2cccc(S(C)(=O)=O)c2)c1)S(=O)(=O)c1ccccc1Cl -US20130296551A1,2,CN.O=C(O)COc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O>>CNC(=O)COc1ccc(Cl)cc1CC1CNC(=O)CN(S(=O)(=O)c2ccc(Cl)cc2)C1=O -US08546501B2,1,CN(C)C(=O)c1ccccc1O.ClCc1ccccc1>>CN(C)C(=O)c1ccccc1OCc1ccccc1 -US20090111862A1,1,N#Cc1ccc(Nn2cnnc2)cc1.O=C(Oc1cc(CBr)ccc1F)c1ccccc1>>N#Cc1ccc(N(Cc2ccc(F)c(OC(=O)c3ccccc3)c2)n2cnnc2)cc1 -US07618985B2,1,BrCCOc1ccccc1.O=c1[nH]ccc2cc(OC3CCNCC3)ccc12>>O=c1[nH]ccc2cc(OC3CCN(CCOc4ccccc4)CC3)ccc12 -US06544985B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2cccn2)c1.CC(C)CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>CC(C)CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3cccn3)c2)cc1C(F)(F)F -US07666864B2,3,CC(=O)NC[C@H]1CN(c2ccc(B3OC(C)(C)C(C)(C)O3)c(F)c2)C(=O)O1.O=[N+]([O-])c1cn2c(n1)OC[C@@H](OCc1ccc(Br)s1)C2>>CC(=O)NC[C@H]1CN(c2ccc(-c3ccc(CO[C@@H]4COc5nc([N+](=O)[O-])cn5C4)s3)c(F)c2)C(=O)O1 -US07893098B2,7,COC(=O)c1cc(C(=O)c2ccccc2)c[nH]1>>COC(=O)c1cc(Cc2ccccc2)c[nH]1 -US04778790,6,CCOC(=O)[C@H](CCCCC1CCNCC1)N[C@H]1CS[C@H](c2cccs2)CN(CC(=O)O)C1=O>>O=C(O)CN1C[C@@H](c2cccs2)SC[C@H](N[C@@H](CCCCC2CCNCC2)C(=O)O)C1=O -US20100210642A1,3,C#Cc1cnc2c(C)cc(-c3ccc(C(F)(F)F)cc3)cn12.NS(=O)(=O)c1cncc(Br)c1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cn2c(C#Cc3cncc(S(N)(=O)=O)c3)cnc12 -US07625913B2,3,Clc1nc(Nc2cc(C3CC3)n[nH]2)c2ccccc2n1.[Mg+]Cc1ccccc1>>c1ccc(Cc2nc(Nc3cc(C4CC4)n[nH]3)c3ccccc3n2)cc1 -US20140148478A1,6,CCOC(=O)c1c(SCC)nc2cnccc2c1C>>CCSc1nc2cnccc2c(C)c1C(=O)O -US20140094472A1,1,CC(=O)[O-].O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1C(=O)OCCl>>CC(=O)OCOC(=O)N1C(=O)CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc21 -US07087778B2,1,COC(=O)[C@@H](C)OS(C)(=O)=O.Nc1ccc(F)c(F)c1F>>COC(=O)[C@H](C)Nc1ccc(F)c(F)c1F -US20130131018A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cccc(F)c1>>CC(C)(C)OC(=O)Nc1cccc(F)c1 -US20050222412A1,9,CCc1cnc(Cl)nc1.NN>>CCc1cnc(NN)nc1 -US06166006,6,COC(=O)C1=Cc2cc(-c3ccsc3)ccc2OCC1>>O=C(O)C1=Cc2cc(-c3ccsc3)ccc2OCC1 -US20140328756A1,7,N#Cc1ccc(CCO)cc1>>NCc1ccc(CCO)cc1 -US04990521,6,CC(CC(C(=O)N(C)C)(c1ccccc1)c1ccccc1)N1CC[C@@H](NC(=O)c2ccccc2OCc2ccccc2)[C@H](O)C1>>CC(CC(C(=O)N(C)C)(c1ccccc1)c1ccccc1)N1CC[C@@H](NC(=O)c2ccccc2O)[C@H](O)C1 -US20060276498A1,1,CC(C)c1cccc(Nc2c(C#N)cnc3cnc(F)cc23)c1.OCCN1CCOCC1>>CC(C)c1cccc(Nc2c(C#N)cnc3cnc(OCCN4CCOCC4)cc23)c1 -US20150038528A1,2,CC(C)(CN)C(=O)O.COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O>>CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(=O)O -US20140171404A1,6,COC(=O)c1cc(Cl)c(Cl)c(Br)c1>>O=C(O)c1cc(Cl)c(Cl)c(Br)c1 -US20100331312A1,1,COc1ccc(CCOS(C)(=O)=O)c(F)c1.C[C@@H]1CCCN1>>COc1ccc(CCN2CCC[C@H]2C)c(F)c1 -US08148383B2,1,C[C@H]1CC(=O)C[C@@H](C)O1.Nc1ncn[nH]1>>C[C@H]1CC(Nc2ncn[nH]2)C[C@@H](C)O1 -US07666888B2,2,Cc1ccc(-c2oncc2C(=O)Cl)cc1.c1ccc(C2CCNCC2)cc1>>Cc1ccc(-c2oncc2C(=O)N2CCC(c3ccccc3)CC2)cc1 -US20140303161A1,1,COc1cc([N+](=O)[O-])ccc1F.Oc1ccc(Cl)c(Cl)c1>>COc1cc([N+](=O)[O-])ccc1Oc1ccc(Cl)c(Cl)c1 -US20040229897A1,2,NCCCCn1cnc2c(N)nc3ccccc3c21.O=C(Cl)c1cccc2cccnc12>>Nc1nc2ccccc2c2c1ncn2CCCCNC(=O)c1cccc2cccnc12 -US20130143892A1,6,CC(C)(C)OC(=O)N1CCC(N(C(=O)c2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)C2CC2)CC1>>CS(=O)(=O)c1ccc(-c2ccc(C(=O)N(C3CCNCC3)C3CC3)cn2)cc1 -US05753660,2,C1CSCCN1.O=C(Cl)CCl>>O=C(CCl)N1CCSCC1 -US20150166505A1,1,CC[O-].Cc1nc(F)ccc1Br>>CCOc1ccc(Br)c(C)n1 -US20050026987A1,6,COC(=O)c1ccc2[nH]c(C(=O)OCc3ccccc3)cc2c1>>COC(=O)c1ccc2[nH]c(C(=O)O)cc2c1 -US04560681,6,CCN(CP(=O)(CCCCc1ccccc1)OCOC(=O)C(C)(C)C)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CCN(CP(=O)(CCCCc1ccccc1)OCOC(=O)C(C)(C)C)C(=O)N1CCC[C@H]1C(=O)O -US20140128425A1,6,COC(=O)CCCCCCCNC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cccn12>>Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)NCCCCCCCC(=O)O -US20050054626A1,6,CC(C)S(=O)(=O)C[C@@H]1C[C@H](NC(C)(C)C)CC[C@@H]1NC(=O)OCc1ccccc1>>CC(C)S(=O)(=O)C[C@@H]1C[C@H](NC(C)(C)C)CC[C@@H]1N -US06265585B1,1,CN1COCNC1=N[N+](=O)[O-].Clc1ncc(CI)s1>>CN1COCN(Cc2cnc(Cl)s2)C1=N[N+](=O)[O-] -US07507740B2,2,CC(C)(C)[Si](C)(C)OCC#CCO.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)OCC#CCOS(C)(=O)=O -US20140057953A1,3,COc1cccc(CN(C)C(=O)c2ccc(Br)s2)c1.COc1ccccc1B(O)O>>COc1cccc(CN(C)C(=O)c2ccc(-c3ccccc3OC)s2)c1 -US20140243336A1,3,Cc1cc(N)nc(Br)c1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>Cc1cc(N)nc(-c2ccnn2C)c1 -US20090044345A1,1,CNCc1ncc(C)c(OC)c1C.Oc1cc(CCl)nc(-c2ccccn2)n1>>COc1c(C)cnc(CN(C)Cc2cc(O)nc(-c3ccccn3)n2)c1C -US07759344B2,3,Cc1cc(NC(=O)c2c(C)n(CC(C)(C)O)n(-c3ccccc3)c2=O)ccc1Br.OB(O)c1cccc2cnccc12>>Cc1cc(NC(=O)c2c(C)n(CC(C)(C)O)n(-c3ccccc3)c2=O)ccc1-c1cccc2cnccc12 -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1c(C)c(OCc2ccc(F)cc2)c(C)c(C)c1C=O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)c(C)c(OCc3ccc(F)cc3)c(C)c1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US20110212968A1,6,CCOC(=O)c1sc(C)nc1-c1ccc(C(F)(F)F)cc1>>Cc1nc(-c2ccc(C(F)(F)F)cc2)c(C(=O)O)s1 -US20130079303A1,1,COc1ccc(Nc2nc(Cl)ncc2I)cn1.NC1CCCC1>>COc1ccc(Nc2nc(NC3CCCC3)ncc2I)cn1 -US20020028835A1,1,NC[C@H](O)COc1cccc2[nH]c(=O)[nH]c12.O=C1CCN(c2ccc(NS(=O)(=O)c3ccc(-n4nnn(CCCC5CCCC5)c4=O)cc3)cc2)CC1>>O=c1[nH]c2cccc(OC[C@@H](O)CNC3CCN(c4ccc(NS(=O)(=O)c5ccc(-n6nnn(CCCC7CCCC7)c6=O)cc5)cc4)CC3)c2[nH]1 -US20120277439A1,8,OCc1ccc(COc2ccccn2)cc1>>O=Cc1ccc(COc2ccccn2)cc1 -US20090093524A1,1,CC(C)c1nnn(-c2c(Cl)cccc2Cl)c1CO.O=Cc1ccc(F)cc1Cl>>CC(C)c1nnn(-c2c(Cl)cccc2Cl)c1COc1ccc(C=O)c(Cl)c1 -US20150274728A1,1,CC#CCn1c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)nc2c1c(=O)[nH]c(=O)n2C.Cc1nc(CCl)nc2ccccc12>>CC#CCn1c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(Cc1nc(C)c3ccccc3n1)c(=O)n2C -US20130317041A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.N#Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1 -US04364958,2,O=C(Nc1ccccc1)C(C(C(=O)O)C1CCCCC1)=S(=O)=O>>O=C1C(=S(=O)=O)C(C2CCCCC2)C(=O)N1c1ccccc1 -US20020193367A1,1,Cc1cc2c(cc1N(C)CC(C)C)N=C(c1cccc(-n3nncc3CO)c1)CC(=O)N2.NCC1CC1>>Cc1cc2c(cc1N(C)CC(C)C)N=C(c1cccc(-n3nncc3CNCC3CC3)c1)CC(=O)N2 -US05990105,1,C1COCCN1.Nc1ccc(S(=O)(=O)c2cc(Br)nc(Br)c2)cc1>>Nc1ccc(S(=O)(=O)c2cc(Br)nc(N3CCOCC3)c2)cc1 -US20120059028A1,6,CCCC(C(=O)OC)c1c(C)nc2sc(CC)c(C)c2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2sc(CC)c(C)c2c1-c1ccc(C)cc1 -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(C)c1=O.CNC(=S)NCCN>>CNC(=S)NCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(C)c1=O -US04963566,1,CN1CCCc2cccc(CCl)c21.COc1ccc2nc(S)[nH]c2c1>>COc1ccc2nc(SCc3cccc4c3N(C)CCC4)[nH]c2c1 -US09073894B2,2,CC(C)(C)OC(=O)N1[C@H](CF)[C@@H](c2ccc(-c3ccc(C(=O)O)nc3)cc2)OC1(C)C.CCN>>CCNC(=O)c1ccc(-c2ccc([C@H]3OC(C)(C)N(C(=O)OC(C)(C)C)[C@@H]3CF)cc2)cn1 -US05543519,3,COCc1c(Br)ncc2[nH]c3ccc(OCc4ccccc4)cc3c12.OB(O)c1ccccc1>>COCc1c(-c2ccccc2)ncc2[nH]c3ccc(OCc4ccccc4)cc3c12 -US07015218B1,1,N#Cc1cc([N+](=O)[O-])ccc1Cl.Oc1ccccc1>>N#Cc1cc([N+](=O)[O-])ccc1Oc1ccccc1 -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc[nH]n3)cc2c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COc1ccc2c(-c3cnn(C)c3)nc(Nc3cc[nH]n3)cc2c1 -US20140110350A1,2,CC(=O)OC(C)=O.O=S(=O)([O-])c1cc2ccccc2[nH]1>>CC(=O)n1c(S(=O)(=O)[O-])cc2ccccc21 -US20070112037A1,4,CC(C)(C)OC(=O)NCCOc1ccc(C(=O)CC(=O)C(F)(F)F)cc1.NNc1ccc2c(c1)OCO2>>CC(C)(C)OC(=O)NCCOc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc3c(c2)OCO3)cc1 -US20070173488A1,2,CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1.Nc1nc2[nH]nc(-n3cncc3-c3ccccc3Cl)c2s1>>CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2nc3[nH]nc(-n4cncc4-c4ccccc4Cl)c3s2)CC1 -US08921389B2,2,CC(C)(C)OC(=O)C(C)(C)CN.COC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O>>CC(C)(C)OC(=O)C(C)(C)CNC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O -US20150246923A1,1,COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(Cl)c12.Cn1nc(C2CC2)cc1N>>COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(Nc3cc(C4CC4)nn3C)c12 -US20080064740A1,1,COc1cc(O)ccc1CNC(=O)OC(C)(C)C.OCCBr>>COc1cc(OCCO)ccc1CNC(=O)OC(C)(C)C -US20100168105A1,1,COC(=O)c1ccc(Br)cc1.O=C(C1CC12CCNCC2)N1CCN(C2CCC2)CC1>>COC(=O)c1ccc(N2CCC3(CC2)CC3C(=O)N2CCN(C3CCC3)CC2)cc1 -US06252084B1,1,CCOC(=O)CCCBr.Cc1c(CC(N)=O)c2c(O)cccc2n1Cc1ccccc1>>CCOC(=O)CCCOc1cccc2c1c(CC(N)=O)c(C)n2Cc1ccccc1 -US05756509,1,Clc1nc2ncnn2c(Cl)c1-c1ccsc1.NC1CCCC1>>Clc1nc2ncnn2c(NC2CCCC2)c1-c1ccsc1 -US08680108B2,1,Brc1ncnc2[nH]cnc12.CC(N)c1ccc2cccnc2c1-c1cncc(F)c1>>CC(Nc1ncnc2[nH]cnc12)c1ccc2cccnc2c1-c1cncc(F)c1 -US07279470B2,2,CC(C)N(C)C1CCNCC1.O=C(Cl)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1>>CC(C)N(C)C1CCN(C(=O)Oc2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)CC1 -US20090030038A1,1,CI.COc1ccc(NS(=O)(=O)c2ccccc2-c2ccc(Cl)cc2)c2c1C[C@@H](CNC(=O)OC(C)(C)C)CC2>>COc1ccc(N(C)S(=O)(=O)c2ccccc2-c2ccc(Cl)cc2)c2c1C[C@@H](CNC(=O)OC(C)(C)C)CC2 -US07196199B2,6,COc1cccc2oc(-c3nc(C)no3)cc12>>Cc1noc(-c2cc3c(O)cccc3o2)n1 -US20110034469A1,2,CC(C)(C)OC(=O)N(C[C@@H]1CN2CCC[C@@H]2CN1)[C@@H]1CCCc2ccccc21.C[C@@H](C(=O)N[C@H](C(=O)O)C1CCCCC1)N(C)C(=O)OC(C)(C)C>>C[C@@H](C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1CN(C(=O)OC(C)(C)C)[C@@H]1CCCc2ccccc21)C1CCCCC1)N(C)C(=O)OC(C)(C)C -US20090227555A2,2,CCc1cnc(-c2cnc(N3CCC(C(=O)O)CC3)c(C)c2)o1.NS(=O)(=O)c1ccc(Cl)s1>>CCc1cnc(-c2cnc(N3CCC(C(=O)NS(=O)(=O)c4ccc(Cl)s4)CC3)c(C)c2)o1 -US20110275673A1,2,CC(C)(C)[Si](C)(C)OCc1ccc(C(=O)NN)cc1.CCCCCCCC(=O)Cl>>CCCCCCCC(=O)NNC(=O)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1 -US06903115B2,2,CS(=O)(=O)c1ccccc1C(=O)O.Clc1ccc(OC2CCN(C3CCNCC3)CC2)cc1Cl>>CS(=O)(=O)c1ccccc1C(=O)N1CCC(N2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1 -US20110076291A1,2,CNCC(C)C.O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2>>CC(C)CN(C)C(=O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2 -US20080193413A1,6,COC(=O)C(C)(CC1CCCCC1)c1ccccc1>>CC(CC1CCCCC1)(C(=O)O)c1ccccc1 -US08927749B2,1,Brc1cccc(-c2cccc(Br)c2)c1.c1ccc2c(c1)[nH]c1ccccc12>>Brc1cccc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)c1 -US20140363452A1,6,COC(=O)[C@@]1(F)CCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CC[C@](F)(C(=O)O)C1 -US04971993,6,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1 -US20020007071A1,4,Nc1cccc(O)c1N.O=C(O)COCc1ccccc1>>Oc1cccc2[nH]c(COCc3ccccc3)nc12 -US06040309,1,ClCc1cccnc1.O=C(O)/C=C/c1ccc(O)cc1>>O=C(O)/C=C/c1ccc(OCc2cccnc2)cc1 -US04734425,2,NCC(=O)O.O=C(Cl)CCc1ccccc1>>O=C(O)CNC(=O)CCc1ccccc1 -US06156761,3,CC1CC(=O)c2c(O)ccc(Br)c2C1.CCCC[Sn](CCCC)(CCCC)c1nccs1>>CC1CC(=O)c2c(O)ccc(-c3nccs3)c2C1 -US20090286785A1,1,N#Cc1cc(Cl)ccn1.Nc1ccc(O)cc1>>N#Cc1cc(Oc2ccc(N)cc2)ccn1 -US04576749,1,CC(=O)NCCN.O=CC(=O)OCc1ccccc1>>CC(=O)NCCNCC(=O)OCc1ccccc1 -US06335341B1,1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.c1cc(C2CCNCC2)ccn1>>CC(C)(C)OC(=O)N1CCC(CN2CCC(c3ccncc3)CC2)CC1 -US20150197523A1,2,CC(C)(C)OC(=O)NC(CC(=O)O)Cc1cc(F)c(F)cc1F.FC(F)(F)c1nnc2n1CCNC2>>CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F -US20060046980A1,6,COCOc1ccc(Cc2c(C)cc(C(=O)OC)cc2C)cc1C(C)C>>COCOc1ccc(Cc2c(C)cc(C(=O)O)cc2C)cc1C(C)C -US20050181988A1,2,CCOC(=O)c1ccc(N2CCN(c3ncccn3)CC2)cc1.NN>>NNC(=O)c1ccc(N2CCN(c3ncccn3)CC2)cc1 -US09085583B2,2,Cc1cc(C)c(CN)c(O)n1.Cc1nn(C(C)c2ccccc2)cc1C(=O)O>>Cc1cc(C)c(CNC(=O)c2cn(C(C)c3ccccc3)nc2C)c(O)n1 -US07345180B2,6,CC(C)(C)C(=O)n1ccc2cc(C(=O)OCc3ccccc3)ccc21>>CC(C)(C)C(=O)n1ccc2cc(C(=O)O)ccc21 -US20060241097A1,9,Clc1nsnc1C1(Cl)CN2CCC1CC2>>Clc1nsnc1C1CN2CCC1CC2 -US04835171,1,CC(C)C=CN(C(=O)Cl)C(C)(C)C.c1cn[nH]c1>>CC(C)C=CN(C(=O)n1cccn1)C(C)(C)C -US20120258993A1,6,C=CCc1c(C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)c2ccccc2n1S(=O)(=O)c1ccc(C)cc1>>C=CCc1c(C(=O)Nc2ccccc2[NH3+])c2ccccc2n1S(=O)(=O)c1ccc(C)cc1 -US08987268B2,2,CC(C)(C)OC(=O)N1CC[C@@H](Nc2c(C(N)=O)cnn3cc(C(=O)O)cc23)C(C)(C)C1.NN>>CC(C)(C)OC(=O)N1CC[C@@H](Nc2c(C(N)=O)cnn3cc(C(=O)NN)cc23)C(C)(C)C1 -US20060194837A1,5,COc1ccc(C2CN(C)Cc3cc(OCC4CCNCC4)ccc32)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(C2CN(C)Cc3cc(OCC4CCN(C(=O)C(F)(F)F)CC4)ccc32)cc1 -US07576100B2,6,C[C@H](CO[Si](C)(C)C(C)(C)C)CN1C(=O)COc2ccc(F)cc21>>C[C@H](CO)CN1C(=O)COc2ccc(F)cc21 -US08183246B2,3,COC(=O)CCCCCNc1ncnc2oc(Br)c(-c3ccc(OC)cc3)c12.OB(O)c1ccc(F)cc1>>COC(=O)CCCCCNc1ncnc2oc(-c3ccc(F)cc3)c(-c3ccc(OC)cc3)c12 -US09067921B2,7,CC1CN(C2(C)CCN(C(=O)OC(C)(C)C)CC2)CCN1C1CC(=O)c2cc(C(F)(F)F)ccc21>>C[C@H]1CN(C2(C)CCN(C(=O)OC(C)(C)C)CC2)CCN1C1CC(O)c2cc(C(F)(F)F)ccc21 -US20090054427A1,9,C=CCOC(=O)C1(Cc2cc(F)c(NC(=O)OCc3ccccc3)c(CCCC)c2)CSCC(NC(=O)OC(C)(C)C)C1=O>>CCCCc1cc(C[C@@H]2CSC[C@H](NC(=O)OC(C)(C)C)C2=O)cc(F)c1NC(=O)OCc1ccccc1 -US04655816,1,CCOC(=O)c1c(Cl)cc(C(F)(F)F)nc1C(F)(F)F.CNC>>CCOC(=O)c1c(N(C)C)cc(C(F)(F)F)nc1C(F)(F)F -US20090093525A1,2,CC1(C)[C@@H](N)[C@@H]1c1ccccc1.COc1ccc(Cl)cc1C(=O)O>>COc1ccc(Cl)cc1C(=O)N[C@H]1[C@H](c2ccccc2)C1(C)C -US20080139576A1,6,COc1ccc(CN2C(=O)CN(c3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OCc4ccccc4)cc3)S2(=O)=O)cc1>>COc1ccc(CN2C(=O)CN(c3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc3)S2(=O)=O)cc1 -US20120165304A1,6,CC(C)=CCN1CCC(NC(=O)C2CN(c3c4c(nc5ccnn35)CCN(C(=O)OC(C)(C)C)CC4)C2)CC1>>CC(C)=CCN1CCC(NC(=O)C2CN(c3c4c(nc5ccnn35)CCNCC4)C2)CC1 -US05296485,1,CNCc1ccccc1.O=CC1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>CN(Cc1ccccc1)CC1CCN(c2ccc([N+](=O)[O-])cc2)CC1 -US20100022538A1,1,N#CBr.Nc1nc(OCc2ccccc2)ncc1F>>N#CNc1nc(OCc2ccccc2)ncc1F -US20060089394A1,1,CCCCC(O)c1cccc(-c2ccc(C(F)(F)F)cc2)n1.CCOC(=O)CCc1ccc(O)cc1>>CCCCC(Oc1ccc(CCC(=O)OCC)cc1)c1cccc(-c2ccc(C(F)(F)F)cc2)n1 -US20130289033A1,3,COc1cccc(B(O)O)c1.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1>>COc1cccc(-c2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 -US20100063067A1,2,CNOC.COc1cc(N2CCC(C(=O)O)CC2)ccc1Cl>>COc1cc(N2CCC(C(=O)N(C)OC)CC2)ccc1Cl -US05331004,2,CN(C)Cc1cccc(N)c1.COC(=O)c1ccc(C(=O)Cl)cc1>>COC(=O)c1ccc(C(=O)Nc2cccc(CN(C)C)c2)cc1 -US04410458,8,CC1(C)S[C@@H]2C(N)C(=O)N2C1C(=O)O.OO>>CC1(C)C(C(=O)O)N2C(=O)C(N)[C@H]2S1=O -US04820697,1,COC(=O)C(C)(C)CC(=O)c1ccc(F)cc1.c1c[nH]cn1>>COC(=O)C(C)(C)CC(=O)c1ccc(-n2ccnc2)cc1 -US20150126449A1,3,Nc1n[nH]c2cccc(Cl)c12.OB(O)c1cccnc1>>Nc1n[nH]c2cccc(-c3cccnc3)c12 -US04698348,4,CC(C)C(=O)O.CNc1c(N)cnc2ccccc12>>CC(C)c1nc2cnc3ccccc3c2n1C -US07094777B2,6,O=S(=O)(CC1CN(C(c2ccccc2)c2ccccc2)C1)c1ccccc1F>>O=S(=O)(CC1CNC1)c1ccccc1F -US20140275129A1,2,COc1ccc2c(c1OC)CCNC2.O=C(O)c1nc(-c2ccc(Cl)cc2)nc2ccccc12>>COc1ccc2c(c1OC)CCN(C(=O)c1nc(-c3ccc(Cl)cc3)nc3ccccc13)C2 -US20130040930A1,2,CCOC(=O)c1ccc(-n2cnc3cccnc32)cc1.Cc1ccc(C(=O)C2CCNCC2)c(C)c1>>Cc1ccc(C(=O)C2CCN(C(=O)c3ccc(-n4cnc5cccnc54)cc3)CC2)c(C)c1 -US05753648,7,O=C1Nc2sccc2Cn2cccc21>>c1cc2n(c1)Cc1ccsc1NC2 -US20090018131A1,1,C1COCCN1.Clc1ncnc2ccc(Br)cc12>>Brc1ccc2ncnc(N3CCOCC3)c2c1 -US04259336,2,COC(=O)C1=C(O)c2sc3ccccc3c2S(=O)(=O)N1C.Nc1ncc(Cl)s1>>CN1C(C(=O)Nc2ncc(Cl)s2)=C(O)c2sc3ccccc3c2S1(=O)=O -US20110213143A1,1,CC(C)(C)OC(=O)N1CCCC(Cc2ncn3c2CCc2cc(O)ccc2-3)C1=O.CCI>>CCOc1ccc2c(c1)CCc1c(CC3CCCN(C(=O)OC(C)(C)C)C3=O)ncn1-2 -US04262013,3,CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CC=Cc1ccc(OCc2ccccc2)cc1>>CC(=O)C=CC=Cc1ccc(OCc2ccccc2)cc1 -US07135472B2,2,CN(C)CC(=O)O.C[C@H](N)c1cccc(-c2cccnc2)c1>>C[C@H](NC(=O)CN(C)C)c1cccc(-c2cccnc2)c1 -US20100210570A1,1,CC(O)c1ccc(Br)nc1.CNC>>CC(c1ccc(Br)nc1)N(C)C -US20100216813A1,2,CCCCS(=O)(=O)Cl.N#Cc1ccc(N(CC2CCCCC2)[C@H]2CCNC2)cc1Cl>>CCCCS(=O)(=O)N1CC[C@H](N(CC2CCCCC2)c2ccc(C#N)c(Cl)c2)C1 -US20030207868A1,1,CC(C)CCn1c(CCl)nc2cc(CNC(=O)OC(C)(C)C)ccc21.O=C1Nc2ccccc2S(=O)(=O)N1C1CC1>>CC(C)CCn1c(CN2C(=O)N(C3CC3)S(=O)(=O)c3ccccc32)nc2cc(CNC(=O)OC(C)(C)C)ccc21 -US20100240638A1,2,C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)c1ccccc1NCCCCN(C)CCCC(=O)OC.COc1ccc2c(O[C@@H]3C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C3)cc(-c3csc(NC(C)C)n3)nc2c1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3csc(NC(C)C)n3)nc3cc(OC)ccc23)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1NCCCCN(C)CCCC(=O)OC -US04772755,1,C=O.COc1ccc(C#Cc2ccccc2)c(CCC(C)NCCc2ccc(OC)c(OC)c2)c1>>COc1ccc(C#Cc2ccccc2)c(CCC(C)N(C)CCc2ccc(OC)c(OC)c2)c1 -US07994218B2,6,CCOC(=O)[C@H](OCc1ccccc1)C(C)(C)COS(=O)(=O)CCCNC(C)=O>>CCOC(=O)[C@H](O)C(C)(C)COS(=O)(=O)CCCNC(C)=O -US20100286112A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(Cc1ccc(O)cc1F)C(=O)O>>CC(C)(C)OC(=O)NC(Cc1ccc(O)cc1F)C(=O)O -US20040122031A1,1,Clc1cc(Cl)ncn1.Oc1ccccc1>>Clc1cc(Oc2ccccc2)ncn1 -US04609744,1,CN(C)C(=S)Cl.COC(=O)c1ccc2ccc(O)cc2c1>>COC(=O)c1ccc2ccc(OC(=S)N(C)C)cc2c1 -US20100280268A1,7,COC(=O)c1cc(O)cc([N+](=O)[O-])c1>>COC(=O)c1cc(N)cc(O)c1 -US20150232445A1,1,CC(=O)N1c2ccc(Br)c(O)c2CC[C@@H]1C.Clc1ncc2ccccc2n1>>CC(=O)N1c2ccc(Br)c(Oc3ncc4ccccc4n3)c2CC[C@@H]1C -US20090286827A1,1,CI.Cc1c[nH]c(-c2cnc(Nc3ccc(Cl)cc3)c(Cl)c2)n1>>Cc1cn(C)c(-c2cnc(Nc3ccc(Cl)cc3)c(Cl)c2)n1 -US05567670,1,C#CCBr.CN(C)c1nc(=O)n(-c2cc(O)c(Cl)cc2F)c(=O)n1C>>C#CCOc1cc(-n2c(=O)nc(N(C)C)n(C)c2=O)c(F)cc1Cl -US20130197009A1,1,N#Cc1ccc(F)cc1Cl.O=C1CNCCN1>>N#Cc1ccc(N2CCNC(=O)C2)cc1Cl -US06051605,2,Cc1ccc(CCC(=O)O)cc1.NCCCOc1ccccc1>>Cc1ccc(CCC(=O)NCCCOc2ccccc2)cc1 -US20090298811A1,8,CSCCn1c(=O)n(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21.O=C(OO)c1cccc(Cl)c1>>CS(=O)CCn1c(=O)n(C(=O)N[C@H](C(N)=O)C(C)(C)C)c2ccccc21 -US20110021498A1,2,CC(C)(C)OC(=O)n1c(-c2cc(C(=O)O)cn(COCC[Si](C)(C)C)c2=O)cc2ccccc21.Nc1cnn(Cc2ccccc2)c1>>CC(C)(C)OC(=O)n1c(-c2cc(C(=O)Nc3cnn(Cc4ccccc4)c3)cn(COCC[Si](C)(C)C)c2=O)cc2ccccc21 -US20120238540A1,1,CC(C)(C)OC(=O)Nc1ccc(N)cc1.N#Cc1cc(-c2ccnc(Cl)n2)ccc1OC1CCOCC1>>CC(C)(C)OC(=O)Nc1ccc(Nc2nccc(-c3ccc(OC4CCOCC4)c(C#N)c3)n2)cc1 -US06949551B2,1,CC(=O)c1cc(OCC=C(Cl)Cl)cc(Cl)c1O.OCCCCOc1ccc(C(F)(F)F)cn1>>CC(=O)c1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCCOc1ccc(C(F)(F)F)cn1 -US08003649B2,1,CS(=O)(=O)c1ccccc1C=O.FC(F)(F)c1nnc2ccc(N3CCCNCC3)nn12>>CS(=O)(=O)c1ccccc1CN1CCCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1 -US08569323B2,1,CC(C)N.CCOC(=O)CCl>>CCOC(=O)CNC(C)C -US20130338152A1,3,CC1(C)OB(c2cc(OCC3CCCO3)ccc2F)OC1(C)C.Nc1ncnc2c1c(I)cn2[C@@H]1C[C@H](CN2C[C@@H]3C[C@H]2CS3=O)C1>>Nc1ncnc2c1c(-c1cc(OCC3CCCO3)ccc1F)cn2[C@@H]1C[C@H](CN2C[C@@H]3CC2C[S@@]3=O)C1 -US20070254866A1,1,COc1c(F)c(F)c(N)c2c(=O)c(C(=O)O)c(-c3ccccc3)n(C3CC3)c12.NCCNc1ccccn1>>COc1c(NCCNc2ccccn2)c(F)c(N)c2c(=O)c(C(=O)O)c(-c3ccccc3)n(C3CC3)c12 -US07723329B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1ccc(OCCCO)cc1CS(=O)(=O)c1cccc2ccccc12>>Cc1ccc(S(=O)(=O)OCCCOc2ccc([N+](=O)[O-])c(CS(=O)(=O)c3cccc4ccccc34)c2)cc1 -US20090264445A1,2,CC(C)(C)OC(=O)NC(CC1CCOCC1)C(=O)O.CC(C)(O)Cn1ccc(N)n1>>CC(C)(O)Cn1ccc(NC(=O)C(CC2CCOCC2)NC(=O)OC(C)(C)C)n1 -US20090069299A1,7,CCOC(=O)Cc1c2c(nn1-c1ccccc1)c(=O)[nH]c1ccccc12>>O=c1[nH]c2ccccc2c2c(CCO)n(-c3ccccc3)nc12 -US04740602,7,COC(=O)c1ccc2[nH]cc(CCCCN3CCc4c(sc5ccccc45)C3)c2c1>>OCc1ccc2[nH]cc(CCCCN3CCc4c(sc5ccccc45)C3)c2c1 -US20100256097A1,1,CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(N)s2)c(F)c1.CN1CCN(c2cccc(Br)n2)CC1>>CN1CCN(c2cccc(Nc3sc(-c4c(F)cc(C(C)(C)O)cc4F)cc3C(N)=O)n2)CC1 -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCCC1CCNCC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CCCS(C)(=O)=O)CC1 -US20120184542A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC[C@H](Cc1cccc(F)c1)NC(=O)c1ccc(Cl)c(N)c1>>CC(C)(C)OC(=O)NC[C@H](Cc1cccc(F)c1)NC(=O)c1ccc(Cl)c(N)c1 -US05106976,8,CC(C)CNc1ccccc1CSc1nc2ncccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>CC(C)CNc1ccccc1CS(=O)c1nc2ncccc2[nH]1 -US20060079554A1,1,CC(C)(C)OC(=O)N1CCC(NCc2ccccc2C(F)(F)F)CC1.O=C1CCCC1>>CC(C)(C)OC(=O)N1CCC(N(Cc2ccccc2C(F)(F)F)C2CCCC2)CC1 -US20050131239A1,3,CS(=O)(=O)c1ccc(C2=C(Cl)C(=O)OC2)cc1.OB(O)c1ccccc1>>CS(=O)(=O)c1ccc(C2=C(c3ccccc3)C(=O)OC2)cc1 -US08278482B2,1,CC(C)(CCN1CCCC1)NC(=O)OCc1ccccc1.CI>>CC(C)(CC[N+]1(C)CCCC1)NC(=O)OCc1ccccc1 -US03954837,2,COC(=N)N.O=C=Nc1ccc(Cl)cc1>>COC(=N)NC(=O)Nc1ccc(Cl)cc1 -US20110021500A1,2,CC1(C)CC[C@@H](c2cc(F)cc(F)c2)NC1.O=C(O)c1cc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)ncn1>>CC1(C)CC[C@@H](c2cc(F)cc(F)c2)N(C(=O)c2cc(Nc3ccc4c(c3)CC3(C4)C(=O)Nc4ncccc43)ncn2)C1 -US20150080326A1,6,CC(C)(C)OC(=O)Nc1ccc(C2=NOC(c3ccc(C(F)(F)F)cc3)C2)cc1>>Nc1ccc(C2=NOC(c3ccc(C(F)(F)F)cc3)C2)cc1 -US07196103B2,1,CCOC(=O)c1cc2cc(C(=O)OC(C)C)ccc2[nH]1.Clc1ccc(-c2cc(CBr)no2)s1>>CCOC(=O)c1cc2cc(C(=O)OC(C)C)ccc2n1Cc1cc(-c2ccc(Cl)s2)on1 -US20100029729A1,6,CCOC(=O)CCc1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)c(F)ccc12>>CC(C)Oc1ccc(-c2nc(-c3c(F)ccc4c(CCC(=O)O)c[nH]c34)no2)cc1C#N -US20110059957A1,6,COC(=O)c1ccc(CCc2ccc(N3CCN(C(C)=O)CC3)cn2)s1>>CC(=O)N1CCN(c2ccc(CCc3ccc(C(=O)O)s3)nc2)CC1 -US20070149547A1,2,Cc1cccc(C(=O)O)n1.Nc1cccc(Br)n1>>Cc1cccc(C(=O)Nc2cccc(Br)n2)n1 -US20050054627A1,6,COC(=O)[C@@H]1C[C@H](N(C)C(C)(C)C)CC[C@@H]1N1CC[C@H](NC(=O)OCc2ccccc2)C1=O>>COC(=O)[C@@H]1C[C@H](N(C)C(C)(C)C)CC[C@@H]1N1CC[C@H](N)C1=O -US20110263571A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(O)c1ccc(Br)cc1F>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Br)cc2F)CC1 -US05952386,2,NCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl.O=C(O)C=Cc1ccc(C(F)(F)F)cc1>>O=C(C=Cc1ccc(C(F)(F)F)cc1)NCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl -US20110105530A1,2,COc1cccc(C(=O)Cl)c1.Nc1cc(C(=O)NCc2ccccc2)ccn1>>COc1cccc(C(=O)Nc2cc(C(=O)NCc3ccccc3)ccn2)c1 -US20060160794A1,1,C1COCCN1.O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1Cl)N1CCC[C@H]1c1ccccc1Cl>>O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCOCC1)N1CCCC1c1ccccc1Cl -US20050004112A1,1,Nc1ccccc1.O=C(Nc1ccccc1N1CCCCC1)c1ccc(Br)o1>>O=C(Nc1ccccc1N1CCCCC1)c1ccc(Nc2ccccc2)o1 -US20150175602A1,6,CC(C)Nc1nc2c(nc1N1CCC(C(F)c3ccc(F)cc3F)CC1)CCN(Cc1ccccc1)C2>>CC(C)Nc1nc2c(nc1N1CCC(C(F)c3ccc(F)cc3F)CC1)CCNC2 -US07368471B2,3,Brc1cccc2c1ccn2Cc1ccccc1.OB(O)c1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(-c2cccc3c2ccn3Cc2ccccc2)cc1 -US20050282862A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.Nc1ccc(I)cc1C(=O)Nc1ccc(Cl)cn1>>CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccc(I)cc2C(=O)Nc2ccc(Cl)cn2)CC1 -US20130225524A1,3,COC(=O)c1cc(N)cc(Br)c1.OB(O)c1ccccc1>>COC(=O)c1cc(N)cc(-c2ccccc2)c1 -US20040024209A1,3,CON(C)C(C)=O.Fc1ccc(CN2CCOCC2)cc1Br>>CC(=O)c1cc(CN2CCOCC2)ccc1F -US06756378B2,6,CCOC(=O)c1ccc(OCCNCCC(=O)Cc2ccc(NC(=O)Nc3ccccc3F)c(OC)c2)c(OC)c1>>COc1cc(CC(=O)CCNCCOc2ccc(C(=O)O)cc2OC)ccc1NC(=O)Nc1ccccc1F -US20050176689A1,6,C#Cc1c(C)c(C#Cc2ccc(CC(=O)OC)cc2)cc(C(C)(C)C)c1OC(C)C>>C#Cc1c(C)c(C#Cc2ccc(CC(=O)O)cc2)cc(C(C)(C)C)c1OC(C)C -US06331636B1,1,NCCCc1ccccc1.NS(=O)(=O)c1cccc2c1CC(=O)CC2>>NS(=O)(=O)c1cccc2c1CC(NCCCc1ccccc1)CC2 -US06369270B1,2,COC(=O)Cl.Nc1c(C(=O)O)ccc(Cl)c1Cl>>COC(=O)Nc1c(C(=O)O)ccc(Cl)c1Cl -US20040023963A1,1,CCN(CC)CCBr.CSc1sc(-c2nc(Nc3cccc(N)c3)ncc2C)c(C2CCCCC2)c1C#N>>CCN(CC)CCNc1cccc(Nc2ncc(C)c(-c3sc(SC)c(C#N)c3C3CCCCC3)n2)c1 -US06432950B1,1,NCc1ccccc1.O=[N+]([O-])c1cc2c(Cl)nc(-c3ccno3)nc2s1>>O=[N+]([O-])c1cc2c(NCc3ccccc3)nc(-c3ccno3)nc2s1 -US07179823B1,6,CCOC(=O)CCc1cn(Cc2ccc(OC3CCN(c4ccccn4)CC3)cc2)nc1OCC>>CCOc1nn(Cc2ccc(OC3CCN(c4ccccn4)CC3)cc2)cc1CCC(=O)O -US07863305B2,1,CS(=O)(=O)OC(CCCl)c1ccccc1.Clc1cccc2[nH]ccc12>>ClCC[C@@H](c1ccccc1)n1ccc2c(Cl)cccc21 -US04100173,1,O=C(O)c1ccc(Cl)cc1I.Oc1cccc(C(F)(F)F)c1>>O=C(O)c1ccc(Cl)cc1Oc1cccc(C(F)(F)F)c1 -US07879852B2,2,CC1(C)CCC(N(C(=O)[C@@H]2CCCO2)[C@H]2C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C2)CC1.CCN>>CCNC(=O)[C@@H]1C[C@H](N(C(=O)[C@@H]2CCCO2)C2CCC(C)(C)CC2)CN1C(=O)OC(C)(C)C -US07393868B2,9,COC(=O)c1ccc(Br)c(N)c1.[C-]#N>>COC(=O)c1ccc(C#N)c(N)c1 -US04589905,2,N#Cc1c(C(=O)O)cnn1-c1ccc(Cl)cc1.NC1CC1>>N#Cc1c(C(=O)NC2CC2)cnn1-c1ccc(Cl)cc1 -US20140343033A1,1,C[C@H](N)c1nc2ccn(C)c2cc1-c1ccnn1C.Fc1cnc(Cl)nc1Cl>>C[C@H](Nc1nc(Cl)ncc1F)c1nc2ccn(C)c2cc1-c1ccnn1C -US07888352B2,2,CC(O)c1cc2nc(Cl)nc(N3CCOCC3)c2s1.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)c1cc2nc(Cl)nc(N3CCOCC3)c2s1 -US20010018449A1,1,Clc1cc(Br)ccc1CBr.O=Cc1[nH]c(-c2ccccc2)nc1Cl>>O=Cc1c(Cl)nc(-c2ccccc2)n1Cc1ccc(Br)cc1Cl -US20090177008A1,1,CN(C)CCCl.COc1ccc(C(=O)NCc2ccc(O)cc2)cc1OC>>COc1ccc(C(=O)NCc2ccc(OCCN(C)C)cc2)cc1OC -US07855292B2,2,COC(=O)c1ccc(Cl)cc1N.O=S(=O)(Cl)c1cccc2nccnc12>>COC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nccnc12 -US05821246,1,CC(=O)Oc1ccc2ncnc(Cl)c2c1.Cc1cc(N)ccc1OCc1ccccn1>>CC(=O)Oc1ccc2ncnc(Nc3ccc(OCc4ccccn4)c(C)c3)c2c1 -US20090118284A1,6,C[Si](C)(C)C#Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12>>C#Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc([N+](=O)[O-])cc12 -US07074801B1,1,CNS(=O)(=O)c1ccc(-c2ncnc3ccc(-c4cn(C(c5ccccc5)(c5ccccc5)c5ccccc5)nc4-c4ccc(F)cc4)cc23)s1.O=C(CCl)N1CCOCC1>>CN(CC(=O)N1CCOCC1)S(=O)(=O)c1ccc(-c2ncnc3ccc(-c4cn(C(c5ccccc5)(c5ccccc5)c5ccccc5)nc4-c4ccc(F)cc4)cc23)s1 -US06166037,1,O=CC1CN(Cc2ccccc2)CC1c1ccccc1.c1ccc(CC2CCNCC2)cc1>>c1ccc(CC2CCN(CC3CN(Cc4ccccc4)CC3c3ccccc3)CC2)cc1 -US20080280855A1,6,CCOC(=O)c1cc2c(nc(C)n2C)c2c1CCC(OC)(c1ccccc1C)O2>>COC1(c2ccccc2C)CCc2c(C(=O)O)cc3c(nc(C)n3C)c2O1 -US20030176405A1,6,C=C[C@@]12CCc3cc(OC)ccc3[C@H]1CC[C@]1(C)C(=O)CC[C@H]12>>C=C[C@@]12CCc3cc(O)ccc3[C@H]1CC[C@]1(C)C(=O)CC[C@H]12 -US20050020616A1,1,CCI.Cc1nc2cc3c(cc2[nH]1)C1CCC3CN(C(=O)OC(C)(C)C)C1>>CCn1c(C)nc2cc3c(cc21)C1CCC3CN(C(=O)OC(C)(C)C)C1 -US07732504B2,1,C=CCC(CC)(C(=O)c1ccc(NCCO)cc1)N(C)C.C=O>>C=CCC(CC)(C(=O)c1ccc(N(C)CCO)cc1)N(C)C -US20090143364A1,2,CCOc1cc(C(C)(C)C#N)c(Cl)cc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCN1CCNCC1>>CCOc1cc(C(C)(C)C#N)c(Cl)cc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CCS(C)(=O)=O)CC1 -US20130274241A1,6,CC(C)(C)OC(=O)N1CCC(n2cc(NC(=O)c3ccc(-n4cc(-c5n[nH]c6ccccc56)nn4)cc3)cn2)CC1>>O=C(Nc1cnn(C2CCNCC2)c1)c1ccc(-n2cc(-c3n[nH]c4ccccc34)nn2)cc1 -US07378417B2,2,CC(C)(CO)NS(=O)(=O)c1cccc(N)c1.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)c(F)c3)nc12>>CC(C)(CO)NS(=O)(=O)c1cccc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)c(F)c4)nc23)c1 -US20100130737A1,6,COC(=O)[C@H](Cc1ccc(OCc2ccc(Cl)cc2)cc1)NC(=O)c1cn2ccc(-c3ccc(Cl)cc3)cc2n1>>O=C(N[C@@H](Cc1ccc(OCc2ccc(Cl)cc2)cc1)C(=O)O)c1cn2ccc(-c3ccc(Cl)cc3)cc2n1 -US07122570B2,6,O=C(NC1(C(=O)O)CCC2(CC1)OCCO2)OCC1c2ccccc2-c2ccccc21>>O=C1CCC(NC(=O)OCC2c3ccccc3-c3ccccc32)(C(=O)O)CC1 -US05166367,1,CCI.O=c1ccc2ccc(OCCCNC[C@H]3COc4cc5c(cc4O3)OCO5)cc2o1>>CCN(CCCOc1ccc2ccc(=O)oc2c1)C[C@H]1COc2cc3c(cc2O1)OCO3 -US07803833B2,1,COc1cc(Br)ccc1O.Fc1ccccc1CBr>>COc1cc(Br)ccc1OCc1ccccc1F -US20060258666A1,7,CC(=O)c1ccc(C2=CCC(C)(C)CC2)c([N+](=O)[O-])c1>>CC(=O)c1ccc(C2=CCC(C)(C)CC2)c(N)c1 -US06124283,2,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.O=C(Cl)c1ccc(Cl)cc1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc(Cl)cc2)CC3)CC1 -US07435744B2,2,Nc1ccc2[nH]c(=S)oc2c1.O=C(O)CN1CCC(Cc2ccccc2)CC1>>O=C(CN1CCC(Cc2ccccc2)CC1)Nc1ccc2[nH]c(=S)oc2c1 -US20050004232A1,1,CC1(C)OC(=O)C(=CC(=O)Cl)O1.CONC(c1ccc(F)cc1)c1ccc(F)cc1>>CON(C(=O)C=C1OC(C)(C)OC1=O)C(c1ccc(F)cc1)c1ccc(F)cc1 -US20150183802A1,6,COC(=O)C(C)=Cc1ccc(F)c(OC)c1>>COc1cc(C=C(C)C(=O)O)ccc1F -US20010023249A1,7,CC(C)(C)OC(=O)Nc1ccc(C#Cc2ccccc2)cc1>>CC(C)(C)OC(=O)Nc1ccc(CCc2ccccc2)cc1 -US06989379B1,6,CC(C)C(=O)NC1CCC(CNC(=S)NC(=O)c2ccccc2)CC1>>CC(C)C(=O)NC1CCC(CNC(N)=S)CC1 -US20080269220A1,1,BrC(c1ccccc1)c1ccccc1.COC(=O)c1ccc(O)c(CC(C)C)c1>>COC(=O)c1ccc(OC(c2ccccc2)c2ccccc2)c(CC(C)C)c1 -US08524917B2,1,CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(O)cc2n1Cc1ccccc1.IC1CCCC1>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OC3CCCC3)cc2n1Cc1ccccc1 -US20130131018A1,2,CC(C)COC(=O)Cl.CCOc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cncc2c1N>>CCOc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cncc2c1NC(=O)OCC(C)C -US07507740B2,3,CC#C[Si](C)(C)C.Nc1c(I)ncnc1Oc1ccccc1>>CC#Cc1ncnc(Oc2ccccc2)c1N -US08399681B2,3,O=C1CSC(N2CCO[C@H](CO)C2)=N1.O=Cc1ccc2c(c1)c(Cl)nn2Cc1ccc(Cl)cc1C(F)(F)F>>O=C1N=C(N2CCOC(CO)C2)SC1=Cc1ccc2c(c1)c(Cl)nn2Cc1ccc(Cl)cc1C(F)(F)F -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2ccnc(C#N)c2)c1.CCc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>CCc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnc(C#N)c3)c2)cc1C(F)(F)F -US04791229,1,N#CCl.Nc1ccc(Cl)c(Cl)c1>>N#CNc1ccc(Cl)c(Cl)c1 -US06355798B1,1,Clc1nn2c(-c3ccccc3)nnc2cc1C1CCC1.c1nc2n(n1)CCNC2>>c1ccc(-c2nnc3cc(C4CCC4)c(N4CCn5ncnc5C4)nn23)cc1 -US08247610B2,6,COC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(N(C)C(CCC(C)C)c2cc(F)cc(F)c2)c1>>CC(C)CCC(c1cc(F)cc(F)c1)N(C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C(CC(C)C)C(=O)O)c1 -US04507311,2,CCOC(=O)N1CCN(C(=S)Cl)CC1.Nc1ccccc1Cc1ncc[nH]1>>CCOC(=O)N1CCN(C(=S)Nc2ccccc2Cc2ncc[nH]2)CC1 -US05633371,7,COc1cc(C(=O)c2ccc(C(F)(F)F)cc2)cc([N+](=O)[O-])c1OC>>COc1cc(C(=O)c2ccc(C(F)(F)F)cc2)cc(N)c1OC -US09150582B2,2,CC(C)(C)CC1(c2ccccc2)OC(=O)C2=C1CNCC2.O=C=NCc1ccccc1>>CC(C)(C)CC1(c2ccccc2)OC(=O)C2=C1CN(C(=O)NCc1ccccc1)CC2 -US20130029980A1,3,CCOCC(=O)OCC.O=Cc1ccc(Cl)cc1>>CCOC(=O)C(=Cc1ccc(Cl)cc1)OCC -US20060177694A1,3,Cc1ccc(B(O)O)cc1.Clc1nccc2ccccc12>>Cc1ccc(-c2nccc3ccccc23)cc1 -US07220784B2,1,COC(=O)CCCOc1cc([N+](=O)[O-])c(CBr)cc1OC.Oc1ccccc1>>COC(=O)CCCOc1cc([N+](=O)[O-])c(COc2ccccc2)cc1OC -US20070185159A1,1,CCOC(=O)c1ccc(Br)cc1C.Oc1ccccc1>>CCOC(=O)c1ccc(Oc2ccccc2)cc1C -US08557809B2,1,CC(C)(C)OC(=O)NCC1CCNCC1.Fc1cc(Br)c2nc(-c3nnc4ccccn34)ccc2c1>>CC(C)(C)OC(=O)NCC1CCN(c2cc(F)cc3ccc(-c4nnc5ccccn45)nc23)CC1 -US06147097,6,CC(O)Cn1c(COCc2ccccc2)nc(C(C)C)c1Sc1cc(Cl)cc(Cl)c1>>CC(O)Cn1c(CO)nc(C(C)C)c1Sc1cc(Cl)cc(Cl)c1 -US20080312192A1,2,CCN1CCNCC1.O=C(O)Cc1ccc([N+](=O)[O-])cc1C(F)(F)F>>CCN1CCN(C(=O)Cc2ccc([N+](=O)[O-])cc2C(F)(F)F)CC1 -US20140128424A1,2,CCCC[C@@H](N)CO.Cc1nc2c(OCc3ccccc3)cccn2c1C(=O)O>>CCCC[C@H](CO)NC(=O)c1c(C)nc2c(OCc3ccccc3)cccn12 -US20110046108A1,9,Nc1cc(Br)cc2c1OCO2.[C-]#N>>N#Cc1cc(N)c2c(c1)OCO2 -US20150005311A1,6,Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(C(=O)OC(C)(C)C)CC(O)C3)cc1>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)NCC(O)C3)cc1 -US04968829,2,CC(C)=CCOc1ccc(SCCN)cc1.CCOC(=O)Cl>>CCOC(=O)NCCSc1ccc(OCC=C(C)C)cc1 -US20090111808A1,3,ClCCCOc1ccc(Br)cc1.OB(O)c1ccncc1>>ClCCCOc1ccc(-c2ccncc2)cc1 -US20080261941A1,6,CC(C)(C)OC(=O)N1CCC(=Cc2cc(Oc3ccc(C(F)(F)F)cn3)cc(C3CC3)c2)CC1>>FC(F)(F)c1ccc(Oc2cc(C=C3CCNCC3)cc(C3CC3)c2)nc1 -US06589977B1,4,NCc1ccccc1.O=C1OC(=O)C(c2c[nH]c3ccccc23)=C1c1c[nH]c2ccccc12>>O=C1C(c2c[nH]c3ccccc23)=C(c2c[nH]c3ccccc23)C(=O)N1Cc1ccccc1 -US07683185B2,10,C/C=C/C=C/C(=O)OC.O=C1CCC(=O)N1Br>>COC(=O)C=CC=CCBr -US20130178494A1,2,Nc1ccc([N+](=O)[O-])cc1.O=C(Cl)CCl>>O=C(CCl)Nc1ccc([N+](=O)[O-])cc1 -US05081131,2,O=C=Nc1ccccc1.c1cc2c3c(cccc3c1)C(NCCCn1ccnc1)=N2>>O=C(Nc1ccccc1)N(CCCn1ccnc1)C1=Nc2cccc3cccc1c23 -US20080167356A1,6,COC(=O)c1cccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CCC4)cc3)ccc12>>O=C(O)c1cccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CCC4)cc3)ccc12 -US20080139631A1,1,CCCc1cc2c(Cl)c(C#N)ccc2[nH]1.Fc1ccc(OCCBr)c(F)c1>>CCCc1cc2c(Cl)c(C#N)ccc2n1CCOc1ccc(F)cc1F -US08735584B2,1,COc1cc2c(=O)[nH]c3nccc(Cl)c3c2cc1OC.COc1cccc(N)c1>>COc1cccc(Nc2ccnc3[nH]c(=O)c4cc(OC)c(OC)cc4c23)c1 -US06982348B2,7,CCOC(=O)C(Cc1ccc(OC(F)(F)F)cc1)C(=O)c1ccc(F)cc1>>CCOC(=O)C(Cc1ccc(OC(F)(F)F)cc1)C(O)c1ccc(F)cc1 -US03975443,1,CC(C)=CCBr.CNC(C)(C)CNC(=O)c1ccccc1>>CC(C)=CCN(C)C(C)(C)CNC(=O)c1ccccc1 -US20140155511A1,1,CC(C)S.O=Cc1ccccc1F>>CC(C)Sc1ccccc1C=O -US20010039351A1,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1.O=S(=O)(CCO)CCCOCCc1ccccc1>>O=C(OCCS(=O)(=O)CCCOCCc1ccccc1)c1ccc([N+](=O)[O-])cc1 -US20150197511A1,1,C1COCCN1.O=[N+]([O-])c1cc(Br)cc(C(F)(F)F)c1>>O=[N+]([O-])c1cc(N2CCOCC2)cc(C(F)(F)F)c1 -US20100137322A1,3,Brc1cccc2c1C[C@H](N(Cc1ccccc1)Cc1ccccc1)CC2.Cc1ncc(B(O)O)cn1>>Cc1ncc(-c2cccc3c2C[C@H](N(Cc2ccccc2)Cc2ccccc2)CC3)cn1 -US20120277229A1,6,O=C(Nc1ccc2c(c1)c(-c1nc3cc(N4CCOCC4)ccc3[nH]1)nn2C1CCCCO1)C1CCC(F)(F)CC1>>O=C(Nc1ccc2[nH]nc(-c3nc4cc(N5CCOCC5)ccc4[nH]3)c2c1)C1CCC(F)(F)CC1 -US05530002,7,O=C(O)CC1=CCc2ccccc21>>OCCC1=CCc2ccccc21 -US20070259869A1,1,CCC(=O)Nc1ccc(S)cc1.CCOC(=O)Cc1cc(Nc2cc(C)[nH]n2)nc(Cl)n1>>CCOC(=O)Cc1cc(Nc2cc(C)[nH]n2)nc(Sc2ccc(NC(=O)CC)cc2)n1 -US20100063286A1,1,CC(C)(C)n1nc(CCC=O)cc1-c1cccs1.Clc1ccc(N2CCNCC2)cc1>>CC(C)(C)n1nc(CCCN2CCN(c3ccc(Cl)cc3)CC2)cc1-c1cccs1 -US20110190227A1,2,CC(C)(C)C(=O)Cl.CCOC(=O)Cc1ccc(OC)c(Cc2ccc(N)cc2CSC(C)(C)C)c1>>CCOC(=O)Cc1ccc(OC)c(Cc2ccc(NC(=O)C(C)(C)C)cc2CSC(C)(C)C)c1 -US20070135452A1,7,CCCN(CCC)c1ccc(C)c([N+](=O)[O-])c1>>CCCN(CCC)c1ccc(C)c(N)c1 -US20100137305A1,3,CC(C)(C)C[Mg+].CC(C)(C)OC(=O)N1CCC(=O)C1>>CC(C)(C)CC1(O)CCN(C(=O)OC(C)(C)C)C1 -US20120157448A1,7,N#Cc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)[C@H]2CC(=O)CC[C@@H]2O3)c1>>N#Cc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)[C@H]2C[C@@H](O)CC[C@@H]2O3)c1 -US20120183537A1,2,NC(=O)NCc1cccc(C(F)(F)F)c1.S=C=Nc1ccc(Cl)c(Cl)c1>>NC(=O)N(Cc1cccc(C(F)(F)F)c1)C(=S)Nc1ccc(Cl)c(Cl)c1 -US20150025068A1,6,CC(=O)Oc1cc(NS(=O)(=O)c2cccc3ccccc23)ccc1C(=O)OCc1ccccc1>>CC(=O)Oc1cc(NS(=O)(=O)c2cccc3ccccc23)ccc1C(=O)O -US20150051197A1,1,Ic1ccccc1.O=S1(=O)CCN2C(=N1)C1(c3ccc(O)cc3)CCC2CC1>>O=S1(=O)CCN2C(=N1)C1(c3ccc(Oc4ccccc4)cc3)CCC2CC1 -US20150025070A1,6,COC(=O)C1CCN(CC(=O)OC(C)(C)C)CC1>>COC(=O)C1CCN(CC(=O)O)CC1 -US20120270865A2,2,CCOc1cccc(-n2cc(C(Nc3ccc(C(=O)O)cc3)C3CCCCC3)c(CC)n2)c1.COC(=O)C(C)CN>>CCOc1cccc(-n2cc(C(Nc3ccc(C(=O)NCC(C)C(=O)OC)cc3)C3CCCCC3)c(CC)n2)c1 -US20080311076A1,3,FC(F)(F)c1cc(N2CCOCC2)ccc1Nc1ncnc2ccc(I)cc12.OB(O)c1cccs1>>FC(F)(F)c1cc(N2CCOCC2)ccc1Nc1ncnc2ccc(-c3cccs3)cc12 -US20060270637A1,2,COC(=O)N(C)CCCCC(=O)O.O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NO[C@H](CO)C3)nc2)c(F)c1>>COC(=O)N(C)CCCCC(=O)OC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1 -US20120129891A1,1,CCOC(=O)C(Br)CC.N#Cc1ccc(O)cc1>>CCOC(=O)C(CC)Oc1ccc(C#N)cc1 -US20020193599A1,6,CCC1=C(C(=O)OCCC#N)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)OCc2ccccc2)=C(CC)N1>>CCC1=C(C(=O)O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)OCCC#N)=C(CC)N1 -US20110046134A1,2,NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1.O=C(O)c1ccc(O)nc1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1ccc(O)nc1 -US05750754,6,COC(=O)CC(COc1ccc(N2CCN(c3ccncc3)CC2)cc1)c1ccccc1>>O=C(O)CC(COc1ccc(N2CCN(c3ccncc3)CC2)cc1)c1ccccc1 -US07078425B2,7,COC(=O)c1ccc(OC)c2c1ccn2S(=O)(=O)c1ccccc1>>COc1ccc(CO)c2ccn(S(=O)(=O)c3ccccc3)c12 -US08877744B2,7,CC1(C)OCC(=O)N[C@](C)(c2cc(C3=CCOCC3)ccc2F)C1(F)F>>CC1(C)OCC(=O)N[C@](C)(c2cc(C3CCOCC3)ccc2F)C1(F)F -US08541576B2,1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.NC(=O)c1n[nH]c2c1CCc1cnc(I)nc1-2>>CC(C)(C)OC(=O)N1CCC(Cn2nc(C(N)=O)c3c2-c2nc(I)ncc2CC3)CC1 -US20100210592A1,3,CC(C)(C)OC(=O)NC(C(=O)c1ccc(I)cc1)c1ccc(Cl)c(Cl)c1.CC(C)Oc1ccc(F)c(B(O)O)c1>>CC(C)Oc1ccc(F)c(-c2ccc(C(=O)C(NC(=O)OC(C)(C)C)c3ccc(Cl)c(Cl)c3)cc2)c1 -US20080103312A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.c1ccc(-c2nnn[nH]2)cc1>>c1ccc(-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20070105890A1,6,COC(=O)c1cc(OC)cc([N+](=O)[O-])c1>>COc1cc(C(=O)O)cc([N+](=O)[O-])c1 -US20140135318A1,1,CCCCN(CCCC)c1n[nH]c(C)c1Cl.CCOC(=O)c1ccc(F)c(C(=O)N2CCc3ccccc3C2)c1>>CCCCN(CCCC)c1nn(-c2ccc(C(=O)OCC)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Cl -US06143769,7,CCCC(NC(=O)Cc1ccc(C(=O)OCC)c(OCC)c1)c1ccccc1N1CCCCC1>>CCCC(NC(=O)Cc1ccc(CO)c(OCC)c1)c1ccccc1N1CCCCC1 -US06225309B1,2,O=C(O)C1CCCN(S(=O)(=O)c2ccc3ccccc3c2)C1.c1cc(N2CCNCC2)ccn1>>O=C(C1CCCN(S(=O)(=O)c2ccc3ccccc3c2)C1)N1CCN(c2ccncc2)CC1 -US04816582,6,CCOC(=O)/C(=N\OCCN=[N+]=[N-])c1csc(N)n1>>[N-]=[N+]=NCCO/N=C(\C(=O)O)c1csc(N)n1 -US06133287,2,CN1CC=C(c2c[nH]c3c(F)cc(F)cc23)CC1.O=S(=O)(Cl)c1ccccc1>>CN1CC=C(c2cn(S(=O)(=O)c3ccccc3)c3c(F)cc(F)cc23)CC1 -US20070155805A1,1,CCCCC(CCBr)c1sc2cc(C(F)(F)F)ccc2c1C.CCOC(=O)Cc1csc(S)n1>>CCCCC(CCSc1nc(CC(=O)OCC)cs1)c1sc2cc(C(F)(F)F)ccc2c1C -US20130029991A1,2,CC(C)(C)OC(=O)N1CCC(CN)CC1.CC(C)(NC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1)C(=O)O>>CC(C)(C)OC(=O)N1CCC(CNC(=O)C(C)(C)NC(=O)c2ccc(S(=O)(=O)Nc3ccccc3Oc3ccccc3)cc2)CC1 -US20110152240A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(Cl)nc2ccnn12>>CC(C)(C)OC(=O)Nc1cc(Cl)nc2ccnn12 -US08232273B2,1,CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)ccc1CCCI.CN1CCC(Nc2ccc(O)cc2)CC1>>CN1CCC(Nc2ccc(OCCCc3ccc(N4CCc5cccc(C(=O)Nc6nc7ccccc7s6)c5C4)nc3C(=O)OC(C)(C)C)cc2)CC1 -US07825126B2,10,Cc1cc(I)ccc1Cl.O=C1CCC(=O)N1Br>>Clc1ccc(I)cc1CBr -US05593983,1,CC1(C)CN([C@H]2C[C@@]3(C)[C@@H](CC[C@H]4[C@@H]5CC[C@H](C(=O)CCl)[C@@]5(C)CC(=O)[C@@H]43)C[C@@H]2O)CCO1.N#C[S-]>>CC1(C)CN([C@H]2C[C@@]3(C)[C@@H](CC[C@H]4[C@@H]5CC[C@H](C(=O)CSC#N)[C@@]5(C)CC(=O)[C@@H]43)C[C@@H]2O)CCO1 -US20090181963A1,1,CN(C)CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3nnn(C4CCNCC4)c3n2)cc1.O=Cc1ccc(F)cc1>>CN(C)CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3nnn(C4CCN(Cc5ccc(F)cc5)CC4)c3n2)cc1 -US20140113882A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@H]1CNCCN1C(=O)OC(C)(C)C>>COC(=O)[C@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)OC(C)(C)C -US20080255111A1,3,CC1(C)OB(c2ccc(O)cc2)OC1(C)C.COC(=O)Cc1ccc(Br)s1>>COC(=O)Cc1ccc(-c2ccc(O)cc2)s1 -US20150232445A1,4,C/C=C/C=O.COc1ccc(Cl)c(N)c1>>COc1ccc(Cl)c2nc(C)ccc12 -US20040122244A1,2,COC1=C(OC)C(=O)C(Cc2cccc(C(=O)O)c2OC(C)=O)=C(C)C1=O.Nc1ccc(C(F)(F)F)cc1>>COC1=C(OC)C(=O)C(Cc2cccc(C(=O)Nc3ccc(C(F)(F)F)cc3)c2OC(C)=O)=C(C)C1=O -US20070088001A1,6,CCOC(=O)C(C[Si](C)(C)C)NC(=O)c1cccc(I)c1>>C[Si](C)(C)CC(NC(=O)c1cccc(I)c1)C(=O)O -US20020045747A1,2,CCC(N)C(=O)OCC(C)C.O=C(O)Cc1ccccc1F>>CCC(NC(=O)Cc1ccccc1F)C(=O)OCC(C)C -US09073882B2,7,N#Cc1ccc(CC(=O)O)c2ccccc12>>N#Cc1ccc(CCO)c2ccccc12 -US20050026836A1,2,CC(C)(C)OC(=O)C(N)Cc1ccccc1.O=C(Cl)c1ccc2c(Cl)cnc(Cl)c2c1>>CC(C)(C)OC(=O)C(Cc1ccccc1)NC(=O)c1ccc2c(Cl)cnc(Cl)c2c1 -US08906946B2,1,CC(N)COc1ccc2ccccc2c1Cl.Cc1ccc(C=O)o1>>Cc1ccc(CNC(C)COc2ccc3ccccc3c2Cl)o1 -US20120184736A1,1,Cc1cccc(C2CC2)c1[O-].Oc1cc(Cl)nnc1Cl>>Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O -US06432950B1,1,NCCc1ccc2c(c1)OCO2.O=[N+]([O-])c1cc2c(Cl)nc(-c3ccno3)nc2s1>>O=[N+]([O-])c1cc2c(NCCc3ccc4c(c3)OCO4)nc(-c3ccno3)nc2s1 -US20110257151A1,6,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(C(=O)N3CCCCC3)c1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(C(=O)N2CCCCC2)c1 -US04871757,1,CCOC(=N)c1ccccc1Cl.CCOC(=O)Cl>>CCOC(=O)N=C(OCC)c1ccccc1Cl -US20100227887A1,2,CCOC(=O)c1cc(C#N)cc(C(F)(F)F)n1.Nc1ccc(Cl)cn1>>N#Cc1cc(C(=O)Nc2ccc(Cl)cn2)nc(C(F)(F)F)c1 -US06653330B2,2,Nc1ccncc1.O=Cc1ccc(C(=O)Cl)cc1>>O=Cc1ccc(C(=O)Nc2ccncc2)cc1 -US05760028,1,CCI.Cc1cc(C(=O)O)ccc1[N+](=O)[O-]>>CCOC(=O)c1ccc([N+](=O)[O-])c(C)c1 -US20060281771A1,6,CC(C)(C)OC(=O)NC1CCN(c2ccnc3ccccc23)C1>>NC1CCN(c2ccnc3ccccc23)C1 -US06251911B1,6,C[C@H](NC(=O)OC(C)(C)C)C(=O)NCc1cccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)c1>>C[C@H](N)C(=O)NCc1cccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)c1 -US08163728B2,2,CC(C)N.Cc1onc(-c2ccc(F)cc2)c1/C=C\c1cc(C(=O)O)n(C)n1>>Cc1onc(-c2ccc(F)cc2)c1/C=C\c1cc(C(=O)NC(C)C)n(C)n1 -US03975537,7,O=C(c1ccc(O)cc1)c1c(-c2cccc([N+](=O)[O-])c2)oc2ccccc12>>Nc1cccc(-c2oc3ccccc3c2C(=O)c2ccc(O)cc2)c1 -US09000044B2,3,COC(=O)Cc1cc2ccc(F)cc2c(B2OC(C)(C)C(C)(C)O2)c1C.FC(F)(F)Oc1ccccc1Sc1ccc(Br)cc1>>COC(=O)Cc1cc2ccc(F)cc2c(-c2ccc(Sc3ccccc3OC(F)(F)F)cc2)c1C -US07326791B2,2,CC1CCCN1.O=C(NCc1nc2cc(Cl)ccc2[nH]1)c1ccc(C(=O)O)c(Cl)c1>>CC1CCCN1C(=O)c1ccc(C(=O)NCc2nc3cc(Cl)ccc3[nH]2)cc1Cl -US20100130538A1,3,CCOC(=O)/C=C/c1cccc2nc(C)cn12.C[S+](C)(C)=O>>CCOC(=O)C1CC1c1cccc2nc(C)cn12 -US20130005728A1,7,N#CCc1ccc(OC(F)(F)F)cc1>>NCCc1ccc(OC(F)(F)F)cc1 -US20100204246A1,1,CC(C)Oc1cc(N)n[nH]1.C[C@H](Nc1nc(F)c(F)cc1[N+](=O)[O-])c1ncc(F)cn1>>CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)c([N+](=O)[O-])cc2F)n[nH]1 -US05449682,9,BrC(Br)(Br)Br.COC(=O)C(Oc1c(Cl)cc(CO)cc1Cl)c1ccccc1>>COC(=O)C(Oc1c(Cl)cc(CBr)cc1Cl)c1ccccc1 -US20050143382A1,1,NNc1nc2nonc2nc1Nc1ccc(F)c(Cl)c1.O=Cc1ccc(-c2cccc([N+](=O)[O-])c2)o1>>O=[N+]([O-])c1cccc(-c2ccc(C=NNc3nc4nonc4nc3Nc3ccc(F)c(Cl)c3)o2)c1 -US07429609B2,2,CC(=O)OC(C)=O.Cc1ncccc1N>>CC(=O)Nc1cccnc1C -US20140274696A1,6,COC(=O)c1nc(-c2ccc(Br)c(F)c2F)cc(NC(C)=O)c1Cl>>COC(=O)c1nc(-c2ccc(Br)c(F)c2F)cc(N)c1Cl -US07153848B2,7,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(C(=O)O)Cc1ccccc1-3>>COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(CO)Cc1ccccc1-3 -US04619996,9,COC(=O)c1c[se]c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1.N>>NC(=O)c1c[se]c([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1 -US20150025093A1,1,CC(C)c1cc2c(Cl)ncnc2s1.NC1CCC(N)CC1>>CC(C)c1cc2c(NC3CCC(N)CC3)ncnc2s1 -US20120295874A1,2,CC(C)(C)OC(=O)NCc1ccc(C(=O)O)cc1.CCOC(=O)COc1ccc(CN)cc1>>CCOC(=O)COc1ccc(CNC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)cc1 -US20100261755A1,7,COC(=O)c1ccnc(-c2ccc(C(F)(F)F)c(F)c2)c1>>COC(=O)C1CCNC(c2ccc(C(F)(F)F)c(F)c2)C1 -US20020147334A1,6,CCOC(=O)C[C@H](Cc1ccc(OCCCNc2ccccn2)cc1)c1ccccc1>>O=C(O)C[C@H](Cc1ccc(OCCCNc2ccccn2)cc1)c1ccccc1 -US20100331317A1,1,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCI)ccc21.NCCc1cccnc1>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCNCCc3cccnc3)ccc21 -US06964983B2,6,COC(=O)COc1ccc(SCc2ccc(Cc3ccc(C(F)(F)F)cc3)cc2)c2c1CCC2>>O=C(O)COc1ccc(SCc2ccc(Cc3ccc(C(F)(F)F)cc3)cc2)c2c1CCC2 -US20080194576A1,1,C#CCO.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](C=CCO)(CCCC)CCCC -US20110118238A1,7,CCOc1cc(OCCN(C)C)ccc1[N+](=O)[O-]>>CCOc1cc(OCCN(C)C)ccc1N -US20110003787A1,6,COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C(=O)OCc3ccccc3)[nH]2)c1>>COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C(=O)O)[nH]2)c1 -US20040063975A1,7,CC(=O)Oc1cc2cc(C(=O)CN3CCOCC3)oc2c(C)c1C>>Cc1c(O)cc2cc(C(=O)CN3CCOCC3)oc2c1C -US20070208053A1,2,NCc1ccccc1F.O=C(O)c1ccc(-c2ccnc3[nH]ccc23)cc1>>O=C(NCc1ccccc1F)c1ccc(-c2ccnc3[nH]ccc23)cc1 -US20040072871A1,6,CCOC(=O)CC(C)NC(=O)c1cc(-c2ccc(OC(F)(F)F)cc2)cs1>>CC(CC(=O)O)NC(=O)c1cc(-c2ccc(OC(F)(F)F)cc2)cs1 -US20140275087A1,7,COc1ccc([C@@H]2CN(Cc3ccccc3)C[C@H]2[N+](=O)[O-])cc1>>COc1ccc([C@@H]2CN(Cc3ccccc3)C[C@H]2N)cc1 -US20090124596A1,6,COC(=O)c1cccc(-n2c(=O)n([C@@H]3CC[C@H](NC(=O)OC(C)(C)C)CC3)c(=O)c3cc(F)cnc32)c1>>COC(=O)c1cccc(-n2c(=O)n([C@@H]3CC[C@H](N)CC3)c(=O)c3cc(F)cnc32)c1 -US20040157850A1,1,CCOC(=O)CCCCOc1ccc2c(c1)CCCN2.COc1cccc(C(=O)N2c3ccccc3C(O)CC2C)c1>>CCOC(=O)CCCCOc1ccc2c(c1)CCCN2C1CC(C)N(C(=O)c2cccc(OC)c2)c2ccccc21 -US20120059002A1,2,Cc1cc(N)no1.O=C(Cl)CBr>>Cc1cc(NC(=O)CBr)no1 -US08906612B2,6,COC(=O)c1c(OCCCS(=O)(=O)O)c(C#CCNC(=O)OC(C)(C)C)c(OCCCS(=O)(=O)O)c(C#CCNC(=O)OC(C)(C)C)c1OCCCS(=O)(=O)O>>CC(C)(C)OC(=O)NCC#Cc1c(OCCCS(=O)(=O)O)c(C#CCNC(=O)OC(C)(C)C)c(OCCCS(=O)(=O)O)c(C(=O)O)c1OCCCS(=O)(=O)O -US09040522B2,2,Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O.NCC1CCCO1>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)NCC3CCCO3)cn2)c1O -US04988664,2,CCCCCCC(=O)Cl.Nc1cccc2c1C(=O)c1ccccc1C2=O>>CCCCCCC(=O)Nc1cccc2c1C(=O)c1ccccc1C2=O -US08158626B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Clc1nc(N2CCOCC2)c2nc(I)sc2n1>>Nc1ccc(-c2nc3c(N4CCOCC4)nc(Cl)nc3s2)cn1 -US08288419B2,1,CC(=O)CCCCBr.O=[N+]([O-])c1cn[nH]c1>>CC(=O)CCCCn1cc([N+](=O)[O-])cn1 -US20120197027A1,1,COc1cc2c(Oc3ccc4[nH]c(C)c(C)c4c3)ncnc2cc1O.O=S1(=O)CCN(CCCO)CC1>>COc1cc2c(Oc3ccc4[nH]c(C)c(C)c4c3)ncnc2cc1OCCCN1CCS(=O)(=O)CC1 -US20060142570A1,1,COc1cc2ncnc(Cl)c2cc1OCCCN1CCN(C)CC1.Nc1ccc2nc(NC(=O)c3ccccc3)sc2c1>>COc1cc2ncnc(Nc3ccc4nc(NC(=O)c5ccccc5)sc4c3)c2cc1OCCCN1CCN(C)CC1 -US20080318940A1,3,C=CCN(C(C)=O)c1ccc2c(=O)n(-c3ccc(Cl)cc3)c(C(C)C)nc2c1C=C>>CC(=O)N1CC=Cc2c1ccc1c(=O)n(-c3ccc(Cl)cc3)c(C(C)C)nc21 -US20150197532A1,7,CNc1ccc(I)cc1[N+](=O)[O-]>>CNc1ccc(I)cc1N -US20140114068A1,9,CC(C)c1ccc2c(c1)OC1(O)c3ccccc3C(=O)C21Cl.N>>CC(C)c1ccc2c(c1)OC1(O)c3ccccc3C(=O)C21N -US20120014997A1,1,C[C@H]1CNC[C@@H](C)O1.O=C(c1ccncc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(Br)cc1>>C[C@H]1CN(c2ccc(S(=O)(=O)Nc3ccc(Cl)cc3C(=O)c3ccncc3)cc2)C[C@@H](C)O1 -US04363762,9,NO.O=Cc1ncn2c1[C@@H]1CCCN1C(=O)c1ccccc1-2>>O=C1c2ccccc2-n2cnc(C=NO)c2[C@@H]2CCCN12 -US06951879B2,1,C1CCNC1.O=S1(=O)N=C(c2ccc(Cl)cc2)c2ccc(OCCCCBr)cc21>>O=S1(=O)N=C(c2ccc(Cl)cc2)c2ccc(OCCCCN3CCCC3)cc21 -US20120298932A1,2,C=C(C)C(=O)O.O=C(O)c1ccc(-c2ccc(OCCCCCCO)cc2)cc1>>C=C(C)C(=O)OCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 -US07691850B2,6,CC(C)(C)OC(=O)N1C[C@@H](F)[C@H](CNC(=O)OCc2ccccc2)C1>>O=C(NC[C@@H]1CNC[C@@H]1F)OCc1ccccc1 -US08796253B2,7,O=[N+]([O-])c1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)n[nH]1>>Nc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)n[nH]1 -US06831081B2,1,Cc1c(CCl)sc2c1c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C.OC(c1ccccc1)C1CCCN1>>Cc1c(CN2CCC[C@@H]2[C@@H](O)c2ccccc2)sc2c1c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C -US20110098296A1,2,COc1ccccc1C(=O)Cl.Cc1nc(-c2cccc(N)c2)c(-c2ccnc(Nc3ccc4c(c3)CN(C)CC4)n2)s1>>COc1ccccc1C(=O)Nc1cccc(-c2nc(C)sc2-c2ccnc(Nc3ccc4c(c3)CN(C)CC4)n2)c1 -US07550478B2,8,OC1c2cc(C(O)C(F)F)ccc2C=Cc2ncc(Cl)cc21>>O=c1c2cc(C(O)C(F)F)ccc2ccc2ncc(Cl)cc12 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2ccccn2)c1.CCOc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>CCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccccn3)c2)cc1C(F)(F)F -US04600709,6,CCOC(=O)C1Oc2cc(Cl)c(S(=O)(=O)c3ccc(Cl)cc3)cc2O1>>O=C(O)C1Oc2cc(Cl)c(S(=O)(=O)c3ccc(Cl)cc3)cc2O1 -US07507740B2,6,Cc1cc(Nc2ncnc3ccn(CCNC(=O)OC(C)(C)C)c23)ccc1Oc1cccc(OC(F)(F)F)c1>>Cc1cc(Nc2ncnc3ccn(CCN)c23)ccc1Oc1cccc(OC(F)(F)F)c1 -US20130274469A1,2,CC[C@@H](N)CO.Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1>>CC[C@H](CO)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 -US20110112065A1,1,C1CCNC1.O=S(=O)(c1ccc2c(c1)OC(CBr)OC2)C(F)(F)F>>O=S(=O)(c1ccc2c(c1)OC(CN1CCCC1)OC2)C(F)(F)F -US06057345,1,CCI.CCOC(=O)c1ccc(CNCc2cc(Br)ccc2OCc2ccccc2)cc1>>CCOC(=O)c1ccc(CN(CC)Cc2cc(Br)ccc2OCc2ccccc2)cc1 -US20120149677A1,1,O=Cc1cccnc1Cl.Oc1ccc2c(nnn2CC2CC2)c1C(F)(F)F>>O=Cc1cccnc1Oc1ccc2c(nnn2CC2CC2)c1C(F)(F)F -US06303593B1,1,Fc1ccc(C2CCNCC2)cc1.O=C[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccsc1>>Fc1ccc(C2CCN(C[C@@H]3CN(Cc4ccccc4)C[C@H]3c3ccsc3)CC2)cc1 -US20070287721A1,3,C#CCOC1CCCCO1.O=Cc1c(-c2ccc(F)cc2)nn2c(Cl)cccc12>>OC(C#CCOC1CCCCO1)c1c(-c2ccc(F)cc2)nn2c(Cl)cccc12 -US07449456B2,6,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc(C(N)=O)c(NCc4ccccc4)n3)cc2)CC1>>NC(=O)c1cnc(Nc2ccc(N3CCNCC3)cc2)nc1NCc1ccccc1 -US05128348,7,CC1=C(c2ccc(C(C)(C)C)cc2)CCC1=O>>CC1=C(c2ccc(C(C)(C)C)cc2)CCC1O -US20150252047A1,1,CCOc1cc2[nH]ncc2cc1N.CCc1[nH]c2ncnc(Cl)c2c1C>>CCOc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c(CC)c(C)c12 -US20050130941A1,2,CCCCCCCCCCCCCCCC(=O)O.COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(CC1CCCCC1)NC(=O)[C@@H](NC(=O)OC)C(C)C)C(C)C>>CCCCCCCCCCCCCCCC(=O)O[C@@H](CN(CC1CCCCC1)NC(=O)[C@@H](NC(=O)OC)C(C)C)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OC)C(C)C -US20060148858A1,6,COCOCCCc1cn(-c2ccc(Br)cn2)nc1C(C)C>>CC(C)c1nn(-c2ccc(Br)cn2)cc1CCCO -US08673891B2,1,C[C@H](N)c1ccc(F)cc1.Clc1cc(OCC2CC2)cc(Cl)n1>>C[C@H](Nc1cc(OCC2CC2)cc(Cl)n1)c1ccc(F)cc1 -US20150166480A1,2,O=C(O)c1ccc(-c2cnc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cn2)cc1.OC[C@H]1CCCN1>>O=C(c1ccc(-c2cnc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cn2)cc1)N1CCC[C@@H]1CO -US07572934B2,2,CO.O=C(O)CC(c1ccc(O)cc1)C1CC1>>COC(=O)CC(c1ccc(O)cc1)C1CC1 -US07662825B2,1,C#CCO.O=S(=O)(Nc1ncc(Cl)nc1Cl)c1cccc(Cl)c1Cl>>C#CCOc1nc(Cl)cnc1NS(=O)(=O)c1cccc(Cl)c1Cl -US20150175619A1,7,O=[N+]([O-])c1ncccc1OC(F)(F)F>>Nc1ncccc1OC(F)(F)F -US20060128770A1,7,COC(=O)c1ccc(CCc2nc(NC(C)=O)sc2Cc2ccc(S(C)(=O)=O)cc2)cc1>>CC(=O)Nc1nc(CCc2ccc(CO)cc2)c(Cc2ccc(S(C)(=O)=O)cc2)s1 -US20070265298A1,1,Clc1ccc2nc(Cl)sc2c1.Nc1ccc(Br)cc1>>Clc1ccc2nc(Nc3ccc(Br)cc3)sc2c1 -US20120101136A1,1,CN(C)CCCO.Cc1cc(O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1>>Cc1cc(OCCCN(C)C)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 -US20140275083A1,7,CC(C(N)C(=O)O)C(F)(F)F>>CC(C(N)CO)C(F)(F)F -US08188082B2,8,Cc1ccc(OCCO)cc1C>>Cc1ccc(OCC=O)cc1C -US20040147739A1,1,CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(O)ccc3N2)c(O)c2ccccc21.CN(C)CCCl>>CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OCCN(C)C)ccc3N2)c(O)c2ccccc21 -US05650428,6,CCOC(=O)Cc1ccc(NC(=O)C(COc2cccnc2)NS(=O)(=O)c2ccc(Cl)cc2)cc1>>O=C(O)Cc1ccc(NC(=O)C(COc2cccnc2)NS(=O)(=O)c2ccc(Cl)cc2)cc1 -US20050261308A1,6,CC(C)(C)OC(=O)N1CCN(c2cccc(CN3C(=O)CCCc4ccccc43)c2)CC1>>O=C1CCCc2ccccc2N1Cc1cccc(N2CCNCC2)c1 -US20080280855A1,7,Cc1nc2c(O)c(CCC(=O)c3ccccc3)c(C(=O)N3CCC3)cc2n1C>>Cc1nc2c(O)c(CC[C@@H](O)c3ccccc3)c(C(=O)N3CCC3)cc2n1C -US20150191461A1,6,Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnn(CC(=O)OC(C)(C)C)c2)c1>>Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnn(CC(=O)O)c2)c1 -US06492523B2,1,CCOC(=O)CC(=O)CCl.Cc1ccc(C)n1CCO>>CCOC(=O)CC(=O)COCCn1c(C)ccc1C -US20090005353A1,1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.NC1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1>>CC(C)(C)N1C(=O)C(NC2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)=C(c2ccccc2)S1(=O)=O -US07833991B2,6,CCCN(CCC)CCCCN(Cc1ccc(CN(Cc2ccc(C)cn2)Cc2ncc[nH]2)cc1)C(=O)OC(C)(C)C>>CCCN(CCC)CCCCNCc1ccc(CN(Cc2ccc(C)cn2)Cc2ncc[nH]2)cc1 -US07094798B1,3,O=C1NC(=O)c2c1c(I)cc1[nH]c3ccc(O)cc3c21.OB(O)c1cccc(Cl)c1Cl>>O=C1NC(=O)c2c1c(-c1cccc(Cl)c1Cl)cc1[nH]c3ccc(O)cc3c21 -US07741315B2,9,COc1c2c(c3n(c1=O)CCCCN(C)C3=O)CCN(Cc1ccc(F)c(Cl)c1)C2=O>>COc1c2c(c3n(c1=O)CCCCN(C)C3=O)CCN(Cc1ccc(F)cc1)C2=O -US20110275797A1,6,COC(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1O>>CS(=O)(=O)N1CCC(Oc2ccc(C(=O)O)c(O)c2)CC1 -US20080200475A1,2,CCc1cc2c(N3CCNCC3)nc(Cl)nc2s1.O=C(Cl)c1ccc(-c2ccccc2)cc1>>CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(Cl)nc2s1 -US08524702B2,1,CC1(C)OB(c2ccc(C(=O)O)cc2)OC1(C)C.CCOCCl>>CCOCOC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1 -US07999132B2,3,CC(C)(C)OC(=O)c1ccc(Br)cc1NC(=O)c1ccccc1.OB(O)c1ccc(Oc2ccccc2)cc1>>CC(C)(C)OC(=O)c1ccc(-c2ccc(Oc3ccccc3)cc2)cc1NC(=O)c1ccccc1 -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1ccc(-c2cccs2)cc1NC(=O)Nc1c(C)cccc1C)C1CCCCC1>>Cc1cccc(C)c1NC(=O)Nc1cc(-c2cccs2)ccc1C(=O)N[C@H](C(=O)O)C1CCCCC1 -US04971973,6,CCOC(=O)c1ccc(OCCCc2c(N)nc(N)[nH]c2=O)cc1>>Nc1nc(N)c(CCCOc2ccc(C(=O)O)cc2)c(=O)[nH]1 -US06506747B1,2,N#CCCCOc1ccc(C(=O)O)cc1.N#Cc1cc(-c2cccnc2)nn1-c1ccc(N)cc1>>N#CCCCOc1ccc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C#N)cc2)cc1 -US07429609B2,3,Brc1cccnc1.C=Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(C#N)c(OC)c12>>COc1c(C#N)ccc2c1c(/C=C/c1cccnc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20110028509A1,1,Fc1ccc(CBr)c(Cl)c1.N#Cc1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cc1>>N#Cc1ccc(CN(Cc2ccc(F)cc2Cl)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20130225584A1,6,COC(=O)c1cc(C(F)(F)F)c(CN2CCOCC2)cc1OCc1ccccc1>>O=C(O)c1cc(C(F)(F)F)c(CN2CCOCC2)cc1OCc1ccccc1 -US20090227619A1,3,C=O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O>>O=C(O)C1Cc2c([nH]c3ccccc23)CN1 -US20100130446A1,3,CC(C)=Cc1ccc(Br)nc1.CN(C)C=O>>CC(C)=Cc1ccc(C=O)nc1 -US20080300275A1,6,CCN(CC)CCN(CC(OC)OC)C(=O)CCOCCc1ccc2ccccc2c1>>CCN(CC)CCN(CC=O)C(=O)CCOCCc1ccc2ccccc2c1 -US20050239789A1,3,CI.C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3cc(Br)c(C(F)(F)F)cc3N21>>Cc1cc2c(cc1C(F)(F)F)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C -US20060287378A1,6,CC(C)c1c(C(=O)OCc2ccccc2)nc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O1>>CC(C)c1c(C(=O)O)nc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O1 -US06759538B2,7,O=[N+]([O-])c1cccc(-c2nc(-c3c(Cl)cccc3Cl)no2)c1>>Nc1cccc(-c2nc(-c3c(Cl)cccc3Cl)no2)c1 -US20090054407A1,3,CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)C(F)(F)F)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.NC(=O)c1cccc(B(O)O)c1>>CC(C)(C)OC(=O)n1c(-c2ccc(-c3cccc(C(N)=O)c3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21 -US08592399B2,6,COC(=O)C1CN(Cc2ccc(-c3ccc4oc(-c5ccccc5)cc(=O)c4c3)cc2)C1>>O=C(O)C1CN(Cc2ccc(-c3ccc4oc(-c5ccccc5)cc(=O)c4c3)cc2)C1 -US08163740B2,1,C1COCCN1.COc1cccc2c1C(NC1=Nc3ccc(NC(=O)CCl)cc3CO1)CO2>>COc1cccc2c1C(NC1=Nc3ccc(NC(=O)CN4CCOCC4)cc3CO1)CO2 -US20140128373A1,2,CCN(C)S(=O)(=O)Cl.Nc1ccc(F)cc1F>>CCN(C)S(=O)(=O)Nc1ccc(F)cc1F -US04954507,1,CC(C)(C)N1CCNCC1.CC(C)(C)n1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21>>CC(C)(C)N1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C(C)(C)C)CC1 -US20060211698A1,3,COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CC(=O)N3CCOCC3)c2c1.OB(O)c1ccc2ncc(-c3ccccc3)cc2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc4ncc(-c5ccccc5)cc4c3)n(CC(=O)N3CCOCC3)c2c1 -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)Cl.O=C(CNc1nccs1)N1CCNCC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(C(=O)CNc2nccs2)CC1 -US20130178443A1,1,CC1CCCN1.Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3cc(F)ccc3C=O)ccc2n1>>CC1CCCN1Cc1ccc(F)cc1-c1ccc2nc(N)nc(C(=O)N3Cc4ccccc4C3)c2c1 -US20120316161A1,6,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(Cl)cc1>>CCCC(C(=O)O)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(Cl)cc1 -US20080300275A1,6,CCOC(CN(CCc1ccccc1)C(=O)CCOCCc1ccc(Br)cc1)OCC>>O=CCN(CCc1ccccc1)C(=O)CCOCCc1ccc(Br)cc1 -US07511159B2,1,CC(C)(C)OC(=O)N1CCNCC1.CS(=O)(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)N1CCN(C2CN(C(c3ccccc3)c3ccccc3)C2)CC1 -US20090275570A1,3,CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3cc(Br)sc23)C1.OB(O)c1cccc(F)c1>>CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3cc(-c4cccc(F)c4)sc23)C1 -US20050239789A1,3,C#C[Si](C)(C)C.CCOC(=O)Nc1c(I)cccc1OC(F)(F)F>>CCOC(=O)Nc1c(C#C[Si](C)(C)C)cccc1OC(F)(F)F -US04826982,2,CC(=O)OC(C)=O.Nc1ccc(F)c(Cl)c1>>CC(=O)Nc1ccc(F)c(Cl)c1 -US04661479,6,O=CCCC[C@@H](C(=O)OCc1ccccc1)N1C(=O)c2ccccc2C1=O>>O=CCCC[C@@H](C(=O)O)N1C(=O)c2ccccc2C1=O -US05124350,6,CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(CCC(=O)OCC)CC2>>CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CCC)ccc2c1OC(CCC(=O)O)CC2 -US20150031674A1,1,CC1(C)OC[C@H](CCO)O1.CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)[nH]c2n1>>CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CC[C@H]3COC(C)(C)O3)c2n1 -US20100311930A1,1,Cc1ccc(O)c(N)c1.O=Cc1ccc(-c2ccccc2C(F)(F)F)o1>>Cc1ccc(O)c(N=Cc2ccc(-c3ccccc3C(F)(F)F)o2)c1 -US20130261133A1,3,C#C[C@@H](CCCCCCCCC)NC(C)=O.C=C[C@H](O)C#CBr>>C=C[C@H](O)C#CC#C[C@@H](CCCCCCCCC)NC(C)=O -US20020119992A1,9,CC(C)(C)OC(=O)NCc1ccc(Cl)cc1CN=[N+]=[N-]>>CC(C)(C)OC(=O)NCc1ccc(Cl)cc1CN -US20110003787A1,2,COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(C(=O)O)[nH]2)c1.NCCCO>>COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(C(=O)NCCCO)[nH]2)c1 -US04073917,1,CC(C)COc1ccccc1O.CCN(CC)CCCCl>>CCN(CC)CCCOc1ccccc1OCC(C)C -US04806685,9,FC(F)(F)/C(=C(\c1ccccc1)c1ccc(OCCBr)cc1)c1ccccc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCOc1ccc(/C(=C(\c2ccccc2)C(F)(F)F)c2ccccc2)cc1 -US06372770B1,9,COc1ccc(Cc2nc3cc(Cl)cc(CCCO)c3o2)cc1OC>>COc1ccc(Cc2nc3cccc(CCCO)c3o2)cc1OC -US20080171748A1,2,CN(C)C(=O)Cl.COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(C)(C)O)C[C@@H]3c3ccc(OC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(C)(C)OC(=O)N(C)C)C[C@@H]3c3ccc(OC)cc3)cc21 -US20030187023A1,1,CCOC(=O)CN.O=C1CCN(c2ccncc2)CC1>>CCOC(=O)CNC1CCN(c2ccncc2)CC1 -US07759369B2,3,COC(=O)c1cc(Cl)cc(CCl)n1.OB(O)c1cc(Cl)ccc1OCc1ccc(Cl)cc1F>>COC(=O)c1cc(Cl)cc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 -US05342846,1,CCOC(=O)c1cn(C2CC2)c2nc(Cl)c(F)cc2c1=O.c1cn([C@H]2CCNC2)nn1>>CCOC(=O)c1cn(C2CC2)c2nc(N3CC[C@H](n4ccnn4)C3)c(F)cc2c1=O -US20020165275A1,1,BrCc1ccc2ccccc2c1.COC(=O)c1cc(O)cc([N+](=O)[O-])c1>>COC(=O)c1cc(OCc2ccc3ccccc3c2)cc([N+](=O)[O-])c1 -US20090149458A1,3,Cc1nc(Cl)nc(N2CCOCC2)c1[N+](=O)[O-].O=[N+]([O-])c1cccc(B(O)O)c1>>Cc1nc(-c2cccc([N+](=O)[O-])c2)nc(N2CCOCC2)c1[N+](=O)[O-] -US20140296209A1,3,Cc1ccc2c(c1)c1c(n2-c2cccc(Br)c2)CCN(C)C1.OB(O)c1cn[nH]c1>>Cc1ccc2c(c1)c1c(n2-c2cccc(-c3cn[nH]c3)c2)CCN(C)C1 -US06919331B2,1,CC(C)CCn1c(Cn2c(=O)n(C3CC3)c(=O)c3ccccc32)nc2cc(CNC(=O)OC(C)(C)C)ccc21.CI>>CC(C)CCn1c(Cn2c(=O)n(C3CC3)c(=O)c3ccccc32)nc2cc(CN(C)C(=O)OC(C)(C)C)ccc21 -US07220863B2,9,NNc1ncc(Cl)cc1F>>Nc1ncc(Cl)cc1F -US05885985,7,N=C(Nc1cccc([N+](=O)[O-])c1)N1CCCC1>>N=C(Nc1cccc(N)c1)N1CCCC1 -US05475106,2,CC(C)(C)OC(=O)CNc1cccc(SC(F)(F)F)c1.Cc1cccc(NC(=O)NCC(=O)O)c1>>Cc1cccc(NC(=O)NCC(=O)N(CC(=O)OC(C)(C)C)c2cccc(SC(F)(F)F)c2)c1 -US20120295897A1,9,O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C1(O)c1c(O)c(Cl)cc2c1OCCO2>>O=C1C(c2c(O)c(Cl)cc3c2OCCO3)c2ccccc2N1C(c1ccccc1)c1ccccc1 -US20130317024A1,3,COc1ccc(C#N)cc1B(O)O.Cc1ccc(Cl)cc1N1C(=O)c2cc(Br)n(C(C)C)c2C1c1ccc(Cl)cc1>>COc1ccc(C#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O -US20150072970A1,2,CC(=O)NCC1CN(c2ccc(-c3ccc(CO)cc3)c(F)c2)C(=O)O1.CS(=O)(=O)Cl>>CC(=O)NCC1CN(c2ccc(-c3ccc(COS(C)(=O)=O)cc3)c(F)c2)C(=O)O1 -US20080221088A1,4,CCOC(=O)CC(=O)CCl.NC(=S)Nc1ccc(Cl)c(C(F)(F)F)c1>>CCOC(=O)Cc1csc(Nc2ccc(Cl)c(C(F)(F)F)c2)n1 -US20150166480A1,7,CC(C)(C(=O)N1CCC(CN(Cc2ccccc2)c2ccc(Br)cc2)CC1)C(F)(F)F>>CC(C)(CN1CCC(CN(Cc2ccccc2)c2ccc(Br)cc2)CC1)C(F)(F)F -US08173650B2,1,C1CC(C2CNC2)CCO1.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C3CCCCO3)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(C4CCOCC4)C3)n(C3CCCCO3)c2n1 -US06693123B2,2,COC(=O)[C@H](CCSC)NC(=O)c1ccc(CC(=O)O)cc1-c1ccccc1.Nc1ccccn1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(CC(=O)Nc2ccccn2)cc1-c1ccccc1 -US20100137313A1,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cnc1SC.COc1cc(Nc2ncc(Br)c(-n3nc(C(F)(F)F)cc3C)n2)cc(OC)c1>>COC(=O)c1cc(-c2cnc(Nc3cc(OC)cc(OC)c3)nc2-n2nc(C(F)(F)F)cc2C)cnc1SC -US08450336B2,2,NCc1ccc(F)c(F)c1.O=C(O)C(COC(F)F)N(Cc1ccccc1)Cc1ccccc1>>O=C(NCc1ccc(F)c(F)c1)C(COC(F)F)N(Cc1ccccc1)Cc1ccccc1 -US20070208051A1,2,CCOc1cc2c(cc1OC)C(c1ccc(C(=O)O)cc1)=N[C@@H]1CCN(C)C[C@H]21.C[C@H](N)COCc1ccccc1>>CCOc1cc2c(cc1OC)C(c1ccc(C(=O)N[C@@H](C)COCc3ccccc3)cc1)=N[C@@H]1CCN(C)C[C@H]21 -US20150252038A1,6,COC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3ccc(C4CC4)cc3Cl)CC2)cc1F>>O=C(O)c1cc(C2CC2)c(OCC2CCN(Cc3ccc(C4CC4)cc3Cl)CC2)cc1F -US20050192253A1,7,COc1cc([N+](=O)[O-])ccc1C#N>>COc1cc(N)ccc1C#N -US20070254940A1,7,CN1CCCCC1CCn1ccc2cc([N+](=O)[O-])ccc21>>CN1CCCCC1CCn1ccc2cc(N)ccc21 -US07105671B2,8,COC(=O)C(CC1CCCC1O)c1ccc(Cl)c(Cl)c1>>COC(=O)C(CC1CCCC1=O)c1ccc(Cl)c(Cl)c1 -US05539112,2,CC(C)(C)C(=O)Cl.Nc1c(Cl)cc(Br)cc1Cl>>CC(C)(C)C(=O)Nc1c(Cl)cc(Br)cc1Cl -US20140350019A1,3,CON(C)C(=O)c1cc(-c2cccc(F)c2)ccc1F.C[Mg+]>>CC(=O)c1cc(-c2cccc(F)c2)ccc1F -US06211215B1,2,CS(=O)(=O)Cl.OCCCc1ccc(SCc2coc(/C=C/c3ccccc3)n2)cc1>>CS(=O)(=O)OCCCc1ccc(SCc2coc(/C=C/c3ccccc3)n2)cc1 -US20120316147A1,1,C1CC2(COC2)N1.COC(=O)c1ccc(Br)c(OCC2CC2)n1>>COC(=O)c1ccc(N2CCC23COC3)c(OCC2CC2)n1 -US06093732,2,CCOC(=O)c1cnc2c(F)cc(-c3ccccc3C)cc2c1O.NCc1ccc(Cl)cc1>>Cc1ccccc1-c1cc(F)c2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2c1 -US08148367B2,6,CCOC(=O)c1[nH]c(=O)n(C2CCCN(C(=O)OCc3ccccc3)C2)c1-c1ccccc1>>O=C(O)c1[nH]c(=O)n(C2CCCN(C(=O)OCc3ccccc3)C2)c1-c1ccccc1 -US07560558B2,1,COc1cc2c(Cl)ccnc2cc1OCc1ccccc1.Cc1ccc(O)c(I)n1>>COc1cc2c(Oc3ccc(C)nc3I)ccnc2cc1OCc1ccccc1 -US04259469,2,C=CC(=O)Cl.CS(=O)(=O)NCc1ccc(O)cc1>>C=CC(=O)Oc1ccc(CNS(C)(=O)=O)cc1 -US06432975B1,7,O=C1C2CCN(CC2)C1Cc1cncc(Br)c1>>Brc1cncc(CC2CC3CCN2CC3)c1 -US20130331378A1,6,COC(=O)c1cccc(Cc2c(-c3cccc(C(F)(F)F)c3)nn3cc(OC)ccc23)n1>>COc1ccc2c(Cc3cccc(C(=O)O)n3)c(-c3cccc(C(F)(F)F)c3)nn2c1 -US20090221583A1,2,NCC(=O)N1CCN(C(=O)c2cc(F)ccc2C(F)(F)F)CC1.O=C(O)c1cc(-c2ccccc2C(F)(F)F)[nH]n1>>O=C(NCC(=O)N1CCN(C(=O)c2cc(F)ccc2C(F)(F)F)CC1)c1cc(-c2ccccc2C(F)(F)F)[nH]n1 -US05563142,1,CC(C)(C)OC(=O)N1CCN(c2ncncc2N)CC1.CC(C)=O>>CC(C)Nc1cncnc1N1CCN(C(=O)OC(C)(C)C)CC1 -US20040209949A1,2,COCOc1ccc(C2CCCC(N)C2)c(OCOC)c1.CS(=O)(=O)Cl>>COCOc1ccc(C2CCCC(NS(C)(=O)=O)C2)c(OCOC)c1 -US05320776,2,CCCCCCCCC(=O)Cl.O=C(O)c1ccc(-c2ccc(O)cc2)cc1>>CCCCCCCCC(=O)Oc1ccc(-c2ccc(C(=O)O)cc2)cc1 -US09051265B2,2,CC(C)c1cccc([C@H](C)N)c1.COC(=O)C(C)(C)Oc1cccc(Cn2c(C)c(C)c3cc(C(=O)O)ccc32)c1>>COC(=O)C(C)(C)Oc1cccc(Cn2c(C)c(C)c3cc(C(=O)N[C@@H](C)c4cccc(C(C)C)c4)ccc32)c1 -US05214152,2,CCNc1ccc(Cl)nc1.CN=C=O>>CCN(C(=O)NC)c1ccc(Cl)nc1 -US20130190332A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4cc(Br)ccn4c3-c3ccccc3)cc2)CCC1.CC(C)(C)OC(=O)n1cc(B(O)O)cn1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4cc(-c5cnn(C(=O)OC(C)(C)C)c5)ccn4c3-c3ccccc3)cc2)CCC1 -US20070149406A1,9,N.Nc1c(SC(F)(F)F)c(C(=O)O)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl>>NC(=O)c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1SC(F)(F)F -US20070027178A1,7,Cc1ccc(Cl)c2c3c([nH]c12)CCNC3>>Cc1ccc(Cl)c2c1N[C@@H]1CCNC[C@H]21 -US20150011795A1,1,Brc1ccc2ccccc2c1.Cc1ccc(N)c(C)c1>>Cc1ccc(Nc2ccc3ccccc3c2)c(C)c1 -US08273759B2,1,CCC(N)COC.Clc1cc(Nc2nccc(-c3ccnc(Cl)c3)n2)ccn1>>CCC(COC)Nc1cc(-c2ccnc(Nc3ccnc(Cl)c3)n2)ccn1 -US05258392,2,CC(=O)OC(C)=O.Nc1ccc(OC2CN3CCC2CC3)cc1>>CC(=O)Nc1ccc(OC2CN3CCC2CC3)cc1 -US20110105758A1,7,Cc1ccccc1C1=C(C(=O)O)CN(C(=O)OC(C)(C)C)CC1>>Cc1ccccc1C1CCN(C(=O)OC(C)(C)C)CC1C(=O)O -US07084149B2,3,COc1ccc2cc(Br)ccc2c1C(C)=O.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(C)c1c(OC)ccc2cc(Br)ccc12 -US04673686,2,COc1ccc(S(C)(=O)=O)cc1C(=O)O.NCC1CCCN1C12CCC(CC1)C2>>COc1ccc(S(C)(=O)=O)cc1C(=O)NCC1CCCN1C12CCC(CC1)C2 -US20080214579A1,1,Brc1ncccn1.Cc1[nH]nc(C(F)(F)F)c1Cc1sc2c(c1C(=O)N1C[C@](C)(O)CO1)c(=O)n(C)c(=O)n2C(C)C>>Cc1c(Cc2sc3c(c2C(=O)N2C[C@](C)(O)CO2)c(=O)n(C)c(=O)n3C(C)C)c(C(F)(F)F)nn1-c1ncccn1 -US08685970B2,3,O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cccc(C(F)(F)F)c1>>O=C/C=C/c1cccc(C(F)(F)F)c1 -US20090163508A1,2,Fc1ccc(-c2ccnc(N3CCNCC3)n2)c(F)c1.O=C(Nc1cccnn1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnn1)N1CCN(c2nccc(-c3ccc(F)cc3F)n2)CC1 -US07772285B2,6,COC(=O)c1ccc(OC)cc1OC>>COc1ccc(C(=O)O)c(OC)c1 -US20080249137A1,6,CCOc1cc(CC(=O)OC)cc(Oc2ccc(-c3ccccc3)s2)c1>>CCOc1cc(CC(=O)O)cc(Oc2ccc(-c3ccccc3)s2)c1 -US20090099355A1,3,CC(C)(C)[Si](C)(C)O[C@@H](CC[C@H]1C(=O)N(c2ccccc2)[C@@H]1c1ccc(Br)cc1OCc1ccccc1)c1ccc(F)cc1.COP(=O)(OC)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>COP(=O)(OC)c1ccc(-c2ccc([C@@H]3[C@@H](CC[C@H](O[Si](C)(C)C(C)(C)C)c4ccc(F)cc4)C(=O)N3c3ccccc3)c(OCc3ccccc3)c2)cc1 -US20040058965A1,3,CCOC(=O)CP(=O)(OCC)OCC.COCOc1ccc(C=O)c(OCc2ccccc2)c1>>CCOC(=O)/C=C/c1ccc(OCOC)cc1OCc1ccccc1 -US05273999,3,C#CCCCCOc1ccccc1CCC(=O)OC.CCCc1c(OS(=O)(=O)C(F)(F)F)ccc2c1OCCC2=O>>CCCc1c(C#CCCCCOc2ccccc2CCC(=O)OC)ccc2c1OCCC2=O -US20130116243A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-c3n[nH]cc3CC4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-c3n[nH]cc3CC4)cc2)CCC1 -US20100144694A1,1,CC1(C)NN(C2CCCCC2)C1=O.Fc1ccc(Cl)c(CBr)c1>>CC1(C)C(=O)N(C2CCCCC2)N1Cc1cc(F)ccc1Cl -US20120295897A1,6,CC(C)CCN1C(=O)C2(COc3cc(OCc4ccccc4)ccc32)c2ccccc21>>CC(C)CCN1C(=O)C2(COc3cc(O)ccc32)c2ccccc21 -US20130252944A1,7,CCOC(=O)c1nn(Cc2ccc(OC)cc2)cc1I>>COc1ccc(Cn2cc(I)c(CO)n2)cc1 -US20140228363A1,1,COC(=O)c1ccc(F)c(-c2c(F)cc(O)cc2F)n1.OC1CCCOC1>>COC(=O)c1ccc(F)c(-c2c(F)cc(OC3CCCOC3)cc2F)n1 -US07241785B2,6,CCCN(Cc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)c1nc(-c2ccccc2)c(CCC(=O)OC)s1>>CCCN(Cc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)c1nc(-c2ccccc2)c(CCC(=O)O)s1 -US20130005760A1,3,CC(=O)Nc1cc(-n2c(C)cc(=O)c3ccc(Cl)nc32)c(F)cc1Br.Cc1noc(C)c1B(O)O>>CC(=O)Nc1cc(-n2c(C)cc(=O)c3ccc(-c4c(C)noc4C)nc32)c(F)cc1Br -US20150165063A1,6,C=CCOC(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)Nc1ccc(COC(=O)Nc2cc(OCCCCCC(=O)N3C[C@@H](CCl)c4c3cc(OC(=O)N3CCN(C)CC3)c3ccccc43)c(OC)cc2C(=O)N2CCC[C@H]2COC(C)=O)cc1>>C=CCOC(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)Nc1ccc(COC(=O)Nc2cc(OCCCCCC(=O)N3C[C@@H](CCl)c4c3cc(OC(=O)N3CCN(C)CC3)c3ccccc43)c(OC)cc2C(=O)N2CCC[C@H]2CO)cc1 -US20090099172A1,3,Cn1cnc2c(C#N)nc(Cl)cc21.OCCOc1ccc(B(O)O)cc1C(F)(F)F>>Cn1cnc2c(C#N)nc(-c3ccc(OCCO)c(C(F)(F)F)c3)cc21 -US05530138,1,ClCCC12CCCN1CCC2.O=CNc1ccccc1>>O=CN(CCC12CCCN1CCC2)c1ccccc1 -US08895572B2,2,N[C@H]1C[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)cnc21.O=C(O)c1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21>>O=C(N[C@H]1C[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)cnc21)c1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21 -US20020193402A1,6,FC(F)(F)c1cc(CO[C@@H]2CC[C@H]3CC[C@]2(c2ccccc2)N3Cc2ccccc2)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(CO[C@@H]2CC[C@H]3CC[C@]2(c2ccccc2)N3)cc(C(F)(F)F)c1 -US20090298808A1,1,BrCc1ccccc1.O=C1O[C@]2(CCN(C(=O)c3ccc(O)cc3)C2)c2ccccc21>>O=C1O[C@]2(CCN(C(=O)c3ccc(OCc4ccccc4)cc3)C2)c2ccccc21 -US20100130468A1,3,NC(=O)c1cc(Br)cc2c(C3CCS(=O)(=O)C3)c[nH]c12.OB(O)c1ccoc1>>NC(=O)c1cc(-c2ccoc2)cc2c(C3CCS(=O)(=O)C3)c[nH]c12 -US06858651B2,2,CN[C@@H]1CC[C@@H](OCCCCBr)CC1.O=S(=O)(Cl)c1ccc(F)c(F)c1>>CN([C@@H]1CC[C@@H](OCCCCBr)CC1)S(=O)(=O)c1ccc(F)c(F)c1 -US20090181942A1,6,CCOC(=O)CC1CCN(C(=O)C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(F)ccc3-n3cccc32)CC1>>COc1cccc([C@H]2O[C@H](CC(=O)N3CCC(CC(=O)O)CC3)c3cccn3-c3ccc(F)cc32)c1OC -US20130237535A1,3,Cc1cc(B2OC(C)(C)C(C)(C)O2)ccc1C#N.O=C1COC2(CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)CN1C1CC1>>Cc1cc(-c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)ccc1C#N -US20100210642A1,2,CC(C)(N)CO.O=S(=O)(Cl)c1cccc(Br)c1>>CC(C)(CO)NS(=O)(=O)c1cccc(Br)c1 -US07772244B2,3,CC(C)(C)OC(=O)Nc1ccccc1F.CN(C)C=O>>CC(C)(C)OC(=O)Nc1c(F)cccc1C=O -US05750724,1,COc1ccc2[nH]cc(CCCBr)c2c1.NCC1COc2ccccc2O1>>COc1ccc2[nH]cc(CCCNCC3COc4ccccc4O3)c2c1 -US20100210641A1,3,Clc1ccn2c(-c3cccc(-n4cccn4)c3)cnc2c1.OB(O)c1cccnc1>>c1cncc(-c2ccn3c(-c4cccc(-n5cccn5)c4)cnc3c2)c1 -US20150057260A1,1,CNC.NC(=O)c1cc(Cl)nc(Cl)n1>>CN(C)c1cc(C(N)=O)nc(Cl)n1 -US05556855,1,CC(=O)O.COC(=O)c1cc(C=Cc2ccc(S(=O)(=O)O)cc2)ccc1O>>COC(=O)c1cc(C=Cc2ccc(S(=O)(=O)O)cc2)ccc1OC(C)=O -US06683090B1,2,N[C@H]1CN2CCC1CC2.O=C(O)/C=C/c1ccco1>>O=C(/C=C/c1ccco1)N[C@H]1CN2CCC1CC2 -US08673893B2,5,CN1CCN(c2ccc(C(=O)OC(C)(C)C)c(NC3CCOCC3)c2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CN1CCN(c2ccc(C(=O)OC(C)(C)C)c(N(C(=O)C(F)(F)F)C3CCOCC3)c2)CC1 -US20150210682A1,6,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCc3ccccc3)cc1CC2C>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2C -US20110274803A1,1,COc1ccc(CN)cc1.O=C1OCCC1=CO>>COc1ccc(CNC=C2CCOC2=O)cc1 -US20150266881A1,6,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1cccc(C(=O)Nc2ccc(-c3ncccn3)cc2)c1>>N[C@@H]1C[C@H]1c1cccc(C(=O)Nc2ccc(-c3ncccn3)cc2)c1 -US20140134235A1,8,Cc1ccc2ncc(CO)c(Cl)c2c1>>Cc1ccc2ncc(C=O)c(Cl)c2c1 -US07169815B2,2,CCCCCCCCCCCCN.COc1cccc(CN=C=S)c1>>CCCCCCCCCCCCNC(=S)NCc1cccc(OC)c1 -US20130225673A1,7,CC(=O)c1cc2cc(F)ccc2o1>>CCc1cc2cc(F)ccc2o1 -US05932601,3,COc1cc(C=O)ccc1OCc1nc(-c2ccccc2)oc1C.c1ccc([P+](CC2OCCO2)(c2ccccc2)c2ccccc2)cc1>>COc1cc(C=CC2OCCO2)ccc1OCc1nc(-c2ccccc2)oc1C -US20040209921A1,7,COC(=O)c1cc(C#N)ccc1CN(Cc1ncc(Cl)cc1C)C(C)(C)c1ccccn1>>Cc1cc(Cl)cnc1CN(Cc1ccc(C#N)cc1CO)C(C)(C)c1ccccn1 -US08217043B2,1,COC(=O)CC(=O)Cl.COC(=O)c1cc(Br)cn1NCc1ccc(C(F)(F)F)cc1>>COC(=O)CC(=O)N(Cc1ccc(C(F)(F)F)cc1)n1cc(Br)cc1C(=O)OC -US04788305,2,CC(C)(C)C(O)[C@H]1[C@@H](C(=O)O)C1(C)C>>CC(C)(C)[C@@H]1OC(=O)[C@@H]2[C@H]1C2(C)C -US07737136B2,2,Nc1cc2c(cc1Cl)N1CCC[C@@H](NC(=O)C(F)(F)F)[C@H]1c1ccccc1O2.O=S(=O)(Cl)c1ccccc1>>O=C(N[C@@H]1CCCN2c3cc(Cl)c(NS(=O)(=O)c4ccccc4)cc3Oc3ccccc3[C@H]12)C(F)(F)F -US06605626B2,2,CC(C)(C)c1ccc(C(=O)Nc2ccccc2N)cc1.O=C(Cl)c1ccc(Cl)cc1>>CC(C)(C)c1ccc(C(=O)Nc2ccccc2NC(=O)c2ccc(Cl)cc2)cc1 -US20090286834A1,1,CCOC(=O)c1cc(C#N)c(Cl)nc1C.NC1CCC(C(=O)O)C1>>CCOC(=O)c1cc(C#N)c(NC2CCC(C(=O)O)C2)nc1C -US20130338367A1,1,CS.O=C1C(Br)CCCN1c1cnn(-c2cccnc2)c1>>CSC1CCCN(c2cnn(-c3cccnc3)c2)C1=O -US06030975,8,COc1cc(OC)nc(OC(C(=O)O)C(SC)(c2ccccc2)c2ccccc2)n1.OO>>COc1cc(OC)nc(OC(C(=O)O)C(c2ccccc2)(c2ccccc2)S(C)=O)n1 -US07745484B2,1,C#CC(C)(C)Cl.Nc1ccc(Br)cc1>>C#CC(C)(C)Nc1ccc(Br)cc1 -US05736540,2,Cc1ccccc1C(=O)Nc1ccc(C(=O)Cl)cc1.c1ccc2c(c1)Cn1cccc1CN2>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 -US04048313,2,CCN(CC)CCC(=O)O.COc1ccc(S(=O)(=O)N2CCOCC2)cc1N>>CCN(CC)CCC(=O)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1OC -US06329405B1,7,COc1ccc(C(NC(=O)c2ccccc2)c2cccc([N+](=O)[O-])c2)cc1>>COc1ccc(C(NC(=O)c2ccccc2)c2cccc(N)c2)cc1 -US09145375B2,2,CCCN.COC(=O)c1c(Cl)cc(Cl)c(OC)c1[N+](=O)[O-]>>CCCNC(=O)c1c(Cl)cc(Cl)c(OC)c1[N+](=O)[O-] -US04960781,1,CC(=O)C(C)(C)COS(C)(=O)=O.c1nc[nH]n1>>CC(=O)C(C)(C)Cn1cncn1 -US20040053972A1,3,O=Cc1ccc(OCc2ccccc2)cc1.OCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>OCCC=Cc1ccc(OCc2ccccc2)cc1 -US20100168103A1,2,C1CCN(CC2CCNCC2)CC1.O=C(O)CC(c1ccccc1)c1ccccc1>>O=C(CC(c1ccccc1)c1ccccc1)N1CCC(CN2CCCCC2)CC1 -US05534532,8,OCCOCCc1ccccc1>>O=CCOCCc1ccccc1 -US05198449,1,NCc1ccc(F)cc1.O=C(c1ccc(F)cc1)C1CCN(CCc2ccccc2)CC1>>Fc1ccc(CN=C(c2ccc(F)cc2)C2CCN(CCc3ccccc3)CC2)cc1 -US05516783,7,O=C(c1ccc(F)cc1)c1cccs1>>OC(c1ccc(F)cc1)c1cccs1 -US08877779B2,1,O=c1[nH]c2ccccc2n1C1CCN(C2CCC3CCc4cccc2c43)CC1.OCCCBr>>O=c1n(CCCO)c2ccccc2n1C1CCN(C2CCC3CCc4cccc2c43)CC1 -US05760050,1,COc1ccc2c3c(c(=O)oc2c1)CNCC3.O=Cc1ccc(Cl)c(Cl)c1>>COc1ccc2c3c(c(=O)oc2c1)CN(Cc1ccc(Cl)c(Cl)c1)CC3 -US20100004243A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(Br)cn1>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1 -US08686048B2,3,Nc1ccc(Br)cc1OC(F)(F)F.OB(O)c1ccccc1F>>Nc1ccc(-c2ccccc2F)cc1OC(F)(F)F -US20070072847A1,6,CCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(C)c(OCc4ccccc4)c(C)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1>>CCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(C)c(O)c(C)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1 -US20060084643A1,7,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](CCCC(=O)O)C1>>CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](CCCCO)C1 -US20080318950A1,4,NC=O.Nc1cc(F)ccc1C(=O)O>>O=c1[nH]cnc2cc(F)ccc12 -US08580832B2,1,CC(C)c1ccccc1O.O=Cc1ccc(F)cc1>>CC(C)c1ccccc1Oc1ccc(C=O)cc1 -US20060276507A1,10,Br.C=C(C(=O)O)C(C)C>>CC(C)C(CBr)C(=O)O -US20140309193A1,1,CCOC(=O)c1c(O)c(O)c(C(=O)OCC)n1-c1ccc(F)cc1.OCCOCc1ccccc1>>CCOC(=O)c1c(O)c(OCCOCc2ccccc2)c(C(=O)OCC)n1-c1ccc(F)cc1 -US20150051262A1,2,COc1cccc(C[C@]2(C(=O)O)CCCN2C(=O)C2CCCN2C(=O)OCc2ccccc2)c1.C[C@@H](O)[C@H](N)C(N)=O>>COc1cccc(CC2(C(=O)N[C@H](C(N)=O)[C@@H](C)O)CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1 -US20090082463A1,7,COc1cc(CC(=O)NC2CCC(=C3CCCCC3)CC2)ccc1O>>COc1cc(CC(=O)N[C@@H]2CC[C@@H](C3CCCCC3)CC2)ccc1O -US20150166558A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@H](N)c1ccc(O)cc1>>COC(=O)[C@H](NC(=O)OC(C)(C)C)c1ccc(O)cc1 -US06143779,3,COc1ccc(C=O)cc1OCc1ccccc1.O=C1COc2cc(O)ccc21>>COc1ccc(C=C2Oc3cc(O)ccc3C2=O)cc1OCc1ccccc1 -US07452892B2,3,Cc1nc(Cl)cc2nn(Cc3ccc(C(F)(F)F)nc3)c(=O)n12.OB(O)c1ccc(Cl)cc1>>Cc1nc(-c2ccc(Cl)cc2)cc2nn(Cc3ccc(C(F)(F)F)nc3)c(=O)n12 -US20110301211A1,3,Cc1noc(-c2ccc(Br)cc2)c1NC(=O)O[C@H](C)c1ccccc1Cl.N#CCc1ccc(B(O)O)cc1>>Cc1noc(-c2ccc(-c3ccc(CC#N)cc3)cc2)c1NC(=O)O[C@H](C)c1ccccc1Cl -US06218431B1,8,CCCc1c(C(C)C)cc(C(C)C)c(CO)c1-c1ccc(F)cc1OCc1ccccc1>>CCCc1c(C(C)C)cc(C(C)C)c(C=O)c1-c1ccc(F)cc1OCc1ccccc1 -US20020165252A1,6,CC1(C)Cc2nc(C3CCCC3)c(C(F)c3ccc(C(F)(F)F)cc3)c(-c3ccc(F)c(F)c3)c2C(O[Si](C)(C)C(C)(C)C)C1>>CC1(C)Cc2nc(C3CCCC3)c(C(F)c3ccc(C(F)(F)F)cc3)c(-c3ccc(F)c(F)c3)c2C(O)C1 -US20050165058A1,1,COc1ccc(C(=O)NCC2CCNCC2)cc1OCCc1ccc(Cl)cc1Cl.O=C(O)CBr>>COc1ccc(C(=O)NCC2CCN(CC(=O)O)CC2)cc1OCCc1ccc(Cl)cc1Cl -US08754085B2,1,CCOC(=O)CCCCCC=O.Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)NCC=C3)cc1>>CCOC(=O)CCCCCCN1CC=Cc2nc(-c3ccc(C)cc3)c(-c3ccc(C)cc3)nc21 -US08039450B2,1,CCI.N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1O>>CCOc1cc(Oc2ccc3c(c2)COB3O)ccc1C#N -US20090318412A1,1,CC(C)(C)OC(=O)N1CCN2C(=O)c3cc(Br)ccc3OCC2C1.CCNCC>>CCN(CC)c1ccc2c(c1)C(=O)N1CCN(C(=O)OC(C)(C)C)CC1CO2 -US20080171734A1,1,CN1CCC(Br)C1=O.Cc1cnc(NC(=O)c2cc(O)cc(Oc3ccc(C(=O)N4CCC4)nc3)c2)cn1>>Cc1cnc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)nc3)cc(O[C@@H]3CCN(C)C3=O)c2)cn1 -US07714008B2,1,CC(C)c1cc(CCl)ccc1C(C)(C)C.O=C(C[C@@H](c1ccc(O)cc1)c1ccon1)N1C(=O)OC[C@@H]1Cc1ccccc1>>CC(C)c1cc(COc2ccc([C@H](CC(=O)N3C(=O)OC[C@@H]3Cc3ccccc3)c3ccon3)cc2)ccc1C(C)(C)C -US08524717B2,1,CI.O=C(CN[C@@H]1C[C@H]1c1ccccc1)NC1CC1>>CN(CC(=O)NC1CC1)[C@@H]1C[C@H]1c1ccccc1 -US20150203515A1,6,COC(=O)C1CC2CCCC(C1)N2C(=O)c1ccc2nc(N[C@@H]3CC[C@@H](C(C)(C)C)CC3)ncc2c1>>CC(C)(C)[C@@H]1CC[C@@H](Nc2ncc3cc(C(=O)N4C5CCCC4CC(C(=O)O)C5)ccc3n2)CC1 -US20130345181A1,3,C#C[Si](C)(C)C.CN(C)C(=O)Cn1cc(I)cn1>>CN(C)C(=O)Cn1cc(C#C[Si](C)(C)C)cn1 -US07674773B2,2,NCc1cccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)c1.O=C(O)COCCOCCNC(=O)C(O)C(O)C(O)C(O)CO>>O=C(COCCOCCNC(=O)C(O)C(O)C(O)C(O)CO)NCc1cccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)c1 -US07932390B2,9,CCOC(=O)c1cnc(Cl)c2c(COc3cc(-c4nnc(-c5ccc(Cl)cc5)o4)ccc3C)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3cc(-c4nnc(-c5ccc(Cl)cc5)o4)ccc3C)csc12 -US20120022045A1,6,OCC1CCC2(CC1)OCCO2>>O=C1CCC(CO)CC1 -US20140088078A1,2,COC(=O)c1c(N)ccc2c1OCC1CC21.O=S(=O)(Cl)c1ccc(F)cc1F>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2F)ccc2c1OCC1CC21 -US20050148624A1,6,CCC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(=O)(=O)CCCOC2CCCCO2)cc1>>CCC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(=O)(=O)CCCO)cc1 -US04138494,7,c1ccc(-c2c[nH]c3ccccc23)cc1>>c1ccc(C2CNc3ccccc32)cc1 -US06960578B2,3,Brc1nccs1.C#Cc1ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)Nc1ccc(C#Cc2nccs2)cc1[N+](=O)[O-] -US20020143020A1,2,CC[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)Cl.COCCOc1cc(F)c(CO)c(Cl)c1>>CC[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)OCc1c(F)cc(OCCOC)cc1Cl -US20080293716A1,2,NCc1cccc(Oc2ccccc2)c1.O=C(O)c1ccc(-c2ccncc2)s1>>O=C(NCc1cccc(Oc2ccccc2)c1)c1ccc(-c2ccncc2)s1 -US20100029722A1,4,C#Cc1nc(C)c(C(=O)NCc2ccccc2)s1.[N-]=[N+]=NCc1ccccc1>>Cc1nc(-c2cn(Cc3ccccc3)nn2)sc1C(=O)NCc1ccccc1 -US20140057882A1,7,COc1ccc2cc([C@@H](C)C(=O)O[C@@H](Cc3c(Cl)cncc3Cl)c3ccc(OC)c(OC)c3)ccc2c1>>COc1ccc([C@@H](O)Cc2c(Cl)cncc2Cl)cc1OC -US20120015928A1,1,C1COCCN1.O=C1O[C@]2(CCN(C(=O)C3(c4ccc(Cl)cc4)CC3)C2)c2ccccc21>>O=C1O[C@]2(CCN(C(=O)C3(c4ccc(N5CCOCC5)cc4)CC3)C2)c2ccccc21 -US06835846B2,3,C#CC[Mg+].CCCCCCCCC/C(C)=C/CBr>>C#CCC/C=C(\C)CCCCCCCCC -US20050020654A1,6,CCCc1nc2c(C)cc(Br)cc2n1CCOc1ccc(CC2SC(=O)NC2=O)cc1C(=O)OC>>CCCc1nc2c(C)cc(Br)cc2n1CCOc1ccc(CC2SC(=O)NC2=O)cc1C(=O)O -US06809097B1,1,COCCOc1cc2nccc(Cl)c2cc1C#N.Nc1ccc(Cl)cc1F>>COCCOc1cc2nccc(Nc3ccc(Cl)cc3F)c2cc1C#N -US06156905,3,CC1(C)OCCC(C(C)(C)C=O)O1.CC[Mg+]>>CCC(O)C(C)(C)C1CCOC(C)(C)O1 -US05972937,2,CCN1CCCC1CN.CSc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cccc(C(=O)O)c1)CC2>>CCN1CCCC1CNC(=O)c1cccc(NC(=O)N2CCc3cc(SC)c(C(F)(F)F)cc32)c1 -US20040229874A1,3,CN1CCN(c2ccccc2Br)CC1.O=Cc1ccc(B(O)O)cc1>>CN1CCN(c2ccccc2-c2ccc(C=O)cc2)CC1 -US20140243286A1,2,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)O)c1nnc(C)n1-2.C[Si](C)(O)c1cccc(OCCN)c1>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCOc1cccc([Si](C)(C)O)c1)c1nnc(C)n1-2 -US06410561B1,1,CCOC(CBr)OCC.Oc1ccc(OCc2ccccc2)cc1>>CCOC(COc1ccc(OCc2ccccc2)cc1)OCC -US20090149445A1,3,Fc1ccc2c(c1)C(=CBr)c1ccccc1CC2.OB(O)c1cccc(O)c1>>Oc1cccc(C=C2c3ccccc3CCc3ccc(F)cc32)c1 -US06525066B2,8,Cc1c(Cl)ccnc1C(O)C1CC1>>Cc1c(Cl)ccnc1C(=O)C1CC1 -US07884104B2,7,CNc1nc(N2CC[C@H](c3cc(F)c(F)cc3F)[C@@H](NC(=O)OC(C)(C)C)C2)ccc1[N+](=O)[O-]>>CNc1nc(N2CC[C@H](c3cc(F)c(F)cc3F)[C@@H](NC(=O)OC(C)(C)C)C2)ccc1N -US06867299B2,2,COc1cc(NC(=O)C(=O)Nc2cccc(N)c2)ccc1-c1cnco1.CS(=O)(=O)Cl>>COc1cc(NC(=O)C(=O)Nc2cccc(NS(C)(=O)=O)c2)ccc1-c1cnco1 -US04056573,9,C/C(=C/CCC(C)CCO)CO>>CC(C)=CCCC(C)CCO -US20080039450A1,2,CN1CCNCC1.O=C(O)c1cccc(Nc2cncc(-c3ccc(O)cc3)n2)c1>>CN1CCN(C(=O)c2cccc(Nc3cncc(-c4ccc(O)cc4)n3)c2)CC1 -US06858651B2,7,CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C#CCO)CC1>>CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](CCCO)CC1 -US08013166B2,6,COC(=O)C1(CC(=O)OC(C)(C)C)CCOCC1>>COC(=O)C1(CC(=O)O)CCOCC1 -US03963706,7,O=C1CN(C2CCCCC2)CN1c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2CN(C3CCCCC3)CC2=O)cc1 -US20040133008A1,6,Cc1ccc(C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2cccc(NC(=O)OC(C)(C)C)n2)c(N2CCCCC2)n1>>Cc1ccc(C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2cccc(N)n2)c(N2CCCCC2)n1 -US20080287427A1,6,CC(=O)Nc1cc(Oc2ccc3c(C(=O)Nc4ccc(CN5CCN(C)CC5)c(C(F)(F)F)c4)cccc3c2)ncn1>>CN1CCN(Cc2ccc(NC(=O)c3cccc4cc(Oc5cc(N)ncn5)ccc34)cc2C(F)(F)F)CC1 -US20090137653A1,1,O=Cc1cccc(C(F)(F)F)c1.OCCNCCO>>OCCN(CCO)Cc1cccc(C(F)(F)F)c1 -US06362336B1,1,CN.OCc1ccnc(Cl)c1>>CNc1cc(CO)ccn1 -US20150065498A1,3,CB(O)O.N#CC1(c2cccc(Cl)n2)CCN(Cc2cc3c(c4ccccc24)CN([C@H]2CCCC[C@@H]2O)C3=O)CC1>>Cc1cccc(C2(C#N)CCN(Cc3cc4c(c5ccccc35)CN([C@H]3CCCC[C@@H]3O)C4=O)CC2)n1 -US20080139579A1,7,CC(C)(C1CCN(Cc2ccc(F)cc2)C(=O)C1)[N+](=O)[O-]>>CC(C)(N)C1CCN(Cc2ccc(F)cc2)C(=O)C1 -US20130143863A1,6,COc1cncc(N2CCc3cc(Cl)ccc3C2=O)c1>>O=C1c2ccc(Cl)cc2CCN1c1cncc(O)c1 -US08916555B2,1,NC(=O)c1c(Nc2ccc(Br)c(Cl)c2)n[nH]c1N.O=Cc1ccc(O)cc1>>NC(=O)c1c(Nc2ccc(Br)c(Cl)c2)n[nH]c1N=Cc1ccc(O)cc1 -US08093394B2,3,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2cncc(Br)c2)SC[C@H]1OC(C)=O.OB(O)c1ccnc(Cl)c1>>CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2cncc(-c3ccnc(Cl)c3)c2)SC[C@H]1OC(C)=O -US20140235623A1,2,N#Cc1ccc(C(F)(F)F)cc1N.NS(=O)(=O)Cl>>N#Cc1ccc(C(F)(F)F)cc1NS(N)(=O)=O -US06936608B2,3,FC(F)(F)c1cnn2c(Br)cnc2n1.Nc1cccc(B(O)O)c1>>Nc1cccc(-c2cnc3nc(C(F)(F)F)cnn23)c1 -US20100190775A1,7,CCNc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(-c3nnc(COC(C)=O)o3)c1)C2=O>>CCNc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(-c3nnc(CO)o3)c1)C2=O -US20110152315A1,3,C#Cc1cccc(O)c1.COC(=O)CCc1ccc(I)cc1>>COC(=O)CCc1ccc(C#Cc2cccc(O)c2)cc1 -US05071844,2,CS(=O)(=O)Cl.OCCc1ccncn1>>CS(=O)(=O)OCCc1ccncn1 -US20150141427A1,3,CC1(C)OB(c2cncc(C#N)c2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(Br)c1>>N#Cc1cncc(-c2cccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c2)c1 -US20100063013A1,3,CC(C)(F)C[C@@H]1N[C@@](c2ccc(Br)cc2)(C(F)(F)F)C#CCSC[C@@H](C#N)NC1=O.CS(=O)(=O)c1ccc(B(O)O)cc1>>CC(C)(F)C[C@@H]1N[C@@](c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)(C(F)(F)F)C#CCSC[C@@H](C#N)NC1=O -US20090181942A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Cl)cc1O>>CC(C)(C)OC(=O)Nc1ccc(Cl)cc1O -US04752646,3,C=CC[Mg+].Cc1c(C)c2c(c(C)c1OCc1ccccc1)CCC(C)(Cl)O2>>C=CCC1(C)CCc2c(C)c(OCc3ccccc3)c(C)c(C)c2O1 -US06465507B2,3,O=C1Cc2cc(F)ccc2N1.O=Cc1[nH]cc2c1CCNC2=O>>O=C1Nc2ccc(F)cc2C1=Cc1[nH]cc2c1CCNC2=O -US20110144150A1,1,Cc1ccc(C=O)cc1.c1cc2[nH]ncc2cc1NC1CC2CCC1N2>>Cc1ccc(CN2C3CCC2C(Nc2ccc4[nH]ncc4c2)C3)cc1 -US20030199550A1,1,CN(C[C@@H]1CC[C@@H](COCCCCBr)CC1)C(=O)Oc1ccc(Cl)cc1.CNC>>CN(C)CCCCOC[C@@H]1CC[C@@H](CN(C)C(=O)Oc2ccc(Cl)cc2)CC1 -US07618978B2,8,COCC1C2CCC1N(C(=O)OC(C)(C)C)C2CO>>COCC1C2CCC1N(C(=O)OC(C)(C)C)C2C=O -US08507690B2,3,CC(=O)Nc1nc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cs1.COC(=O)/C=C/c1cc(C=O)cs1>>COC(=O)/C=C/c1cc(C=Cc2csc(NC(C)=O)n2)cs1 -US06136852,6,CCOC(=O)CCCCc1ccc2c(c1)C[C@@H](NC(=O)OC(C)(C)C)CC2>>CCOC(=O)CCCCc1ccc2c(c1)C[C@@H](N)CC2 -US20130035310A1,2,Nc1nccs1.O=C(Nc1ccc(S(=O)(=O)Cl)cc1F)C(F)(F)F>>O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1F)C(F)(F)F -US05212182,2,NC1CCN(Cc2ccccc2)CC1.O=C(O)c1ccc(NCc2ccnc3ccccc23)cc1>>O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(NCc2ccnc3ccccc23)cc1 -US20090023729A1,1,CCCNCC1CC1.O=Cc1cc2ccccc2nc1Cl>>CCCN(CC1CC1)c1nc2ccccc2cc1C=O -US08501746B2,2,Cc1cnc(CN)cn1.Cc1nc(-n2ccc(OCc3ccccc3)cc2=O)sc1C(=O)O>>Cc1cnc(CNC(=O)c2sc(-n3ccc(OCc4ccccc4)cc3=O)nc2C)cn1 -US06319924B1,9,Clc1cc(N2CC=CCC2)c(Cl)nn1.NN>>NNc1cc(N2CC=CCC2)c(Cl)nn1 -US07511154B2,6,O=C(N[C@@H]1CC(=O)N(Cc2ccccc2)C1=O)OCc1ccccc1>>N[C@@H]1CC(=O)N(Cc2ccccc2)C1=O -US07169777B2,1,CC(C)(C)OC(=O)N1CCN(C(CN)c2ccccc2F)CC1.CCC(CC)CBr>>CCC(CC)CNCC(c1ccccc1F)N1CCN(C(=O)OC(C)(C)C)CC1 -US20090325930A1,6,CCOC(=O)COc1ccc(C(=O)N(CC)c2cc(OC)ccc2C2CCc3cc(OC)ccc3C2)cc1>>CCN(C(=O)c1ccc(OCC(=O)O)cc1)c1cc(OC)ccc1C1CCc2cc(OC)ccc2C1 -US20070249670A1,6,CCCC[C@H](NC(=O)c1nc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)OC>>CCCC[C@H](NC(=O)c1nc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)O -US05804593,6,COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(OC)cc1>>COc1ccc(S(=O)(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)O)cc1 -US20030236256A1,1,COCC(C)N.Clc1cccc(Nc2nccc(-c3ccnc(Cl)c3)n2)c1>>COCC(C)Nc1cc(-c2ccnc(Nc3cccc(Cl)c3)n2)ccn1 -US20110028509A1,2,NS(=O)(=O)C1CC1.O=C(O)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1>>O=C(NS(=O)(=O)C1CC1)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20100216750A1,3,C[Si](C)(C)C#CCCCCC(=O)c1ncc(-c2ccccn2)o1.FC(F)(F)c1ccc(I)cc1>>O=C(CCCCC#Cc1ccc(C(F)(F)F)cc1)c1ncc(-c2ccccn2)o1 -US20140066455A1,1,C1CNCCN(C2CC2)C1.COc1cc(CCc2cc(NC(=O)c3cnc(Cl)cn3)[nH]n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3cnc(N4CCCN(C5CC5)CC4)cn3)[nH]n2)cc(OC)c1 -US07521449B2,2,O=C(Cl)OCc1ccccc1.O=C(O)C1(c2ccccc2)CCNCC1>>O=C(OCc1ccccc1)N1CCC(C(=O)O)(c2ccccc2)CC1 -US08901156B2,9,BrC(Br)(Br)Br.OCc1cc(-c2ccccc2)n(Cc2ccccc2)n1>>BrCc1cc(-c2ccccc2)n(Cc2ccccc2)n1 -US20020173646A1,1,NC(=O)[C@@H]1CCCN1.OCCCBr>>NC(=O)[C@@H]1CCCN1CCCO -US20080090863A1,2,Cc1cnc(N[C@@H]2CC[C@H](N)CC2)cc1N1CCOCC1.O=C(O)c1ccc(F)c(Cl)c1>>Cc1cnc(N[C@@H]2CC[C@H](NC(=O)c3ccc(F)c(Cl)c3)CC2)cc1N1CCOCC1 -US05254584,6,COC(=O)c1cc(Cl)cc(C(=O)OC)c1>>COC(=O)c1cc(Cl)cc(C(=O)O)c1 -US06200998B1,1,C=CCBr.CCCc1cc(Oc2ccccc2)ccc1O>>C=CCOc1ccc(Oc2ccccc2)cc1CCC -US06376491B1,7,Cc1cc(N=Cc2oc3cccc(OCCCN(C)Cc4cccnc4)c3c2C)no1>>Cc1cc(NCc2oc3cccc(OCCCN(C)Cc4cccnc4)c3c2C)no1 -US05475106,2,CC(=O)Nc1ccccc1N(CC(=O)OC(C)(C)C)C(=O)CN.Cc1cccc(N=C=O)c1>>CC(=O)Nc1ccccc1N(CC(=O)OC(C)(C)C)C(=O)CNC(=O)Nc1cccc(C)c1 -US08470810B2,7,CCC(=O)N1CC(c2ccc(NS(=O)(=O)c3ccc(C(C)C)cc3)cc2)C1>>CCCN1CC(c2ccc(NS(=O)(=O)c3ccc(C(C)C)cc3)cc2)C1 -US07067534B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccc(I)cc3)CC2)c1.NNc1ccc(OC(F)(F)F)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCc3c(-c4ccc(I)cc4)[nH]c4ccc(OC(F)(F)F)cc34)CC2)c1 -US05935985,9,BrC(Br)(Br)Br.COC(=O)COc1cccc(CCCO)c1>>COC(=O)COc1cccc(CCCBr)c1 -US20150197529A1,1,Fc1cc(Br)ccc1CBr.O=S1(=O)NCCCC1c1ccccc1>>O=S1(=O)C(c2ccccc2)CCCN1Cc1ccc(Br)cc1F -US06020531,1,COc1cccc(S)c1.O=CCC1CCCCC1Br>>COc1cccc(SC2CCCCC2CC=O)c1 -US20040181064A1,9,Cc1c(N2C(=O)N3CCC(=O)[C@H]3[C@H]2C(F)(F)F)ccc(C#N)c1Cl.NO>>Cc1c(N2C(=O)N3CCC(=NO)[C@H]3[C@H]2C(F)(F)F)ccc(C#N)c1Cl -US07122535B2,2,CC(C)(C)c1cc(N)cc(C(C)(C)C)c1O.O=C(O)c1ccc(-c2ccc([N+](=O)[O-])cc2)o1>>CC(C)(C)c1cc(NC(=O)c2ccc(-c3ccc([N+](=O)[O-])cc3)o2)cc(C(C)(C)C)c1O -US03953416,2,N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)OCc1ccccc1.O=C1CC[C@@H](C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)N1>>O=C1CC[C@@H](C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccc(OCc3ccccc3)cc2)C(=O)OCc2ccccc2)N1 -US20150175562A1,6,CCOC(=O)c1ncoc1-c1ccc(S(=O)(=O)NC(C)(C)C)c2ccccc12>>CC(C)(C)NS(=O)(=O)c1ccc(-c2ocnc2C(=O)O)c2ccccc12 -US05143643,2,COC(C)CCCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(C)CCCCOS(=O)(=O)c1ccc(C)cc1 -US20130102620A1,2,CC(=O)O.NS(=O)(=O)c1cnn2c(Nc3cccc(Cl)c3Cl)c(C(=O)N3CCC(c4ccc(F)cc4)CC3)cnc12>>CC(=O)NS(=O)(=O)c1cnn2c(Nc3cccc(Cl)c3Cl)c(C(=O)N3CCC(c4ccc(F)cc4)CC3)cnc12 -US20150005305A1,1,O=C(CCl)N(Cc1ccccc1)C[C@@H](O)c1ccc(F)cc1>>O=C1CO[C@@H](c2ccc(F)cc2)CN1Cc1ccccc1 -US20120046267A1,9,CC(C)(C)Sc1c(Br)cccc1C=O.NO>>CC(C)(C)Sc1c(Br)cccc1C=NO -US20080114177A1,9,OCCCCC(I)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>OCCCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F -US20040082570A1,1,CCOC(=O)Cn1c(=O)c2[nH]c(N3CCN(C(=O)OC(C)(C)C)CC3)nc2n(C)c1=O.COc1ccccc1B(O)O>>CCOC(=O)Cn1c(=O)c2c(nc(N3CCN(C(=O)OC(C)(C)C)CC3)n2-c2ccccc2OC)n(C)c1=O -US20110257151A1,6,COC(=O)c1ccc(F)c2c1CC(C)(C)C(c1cccc(N3CCOCC3)c1)N2>>CC1(C)Cc2c(C(=O)O)ccc(F)c2NC1c1cccc(N2CCOCC2)c1 -US20090306062A1,2,C[C@@H]1COCC[C@@H]1C(=O)O.O=C1N[C@H](Cc2ccccc2)CO1>>C[C@H]1COCC[C@@H]1C(=O)N1C(=O)OC[C@H]1Cc1ccccc1 -US05693809,1,CCCCCCI.CN1C(=O)CC[C@]2(C)[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@@H]3CC[C@@H]12>>CCCCCCO[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C -US08252935B2,6,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2)c1>>CC(C)CC(C(=O)O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2)c1 -US20050054712A1,1,BrCc1ccccc1.O=C1Nc2ccccc2C1=O>>O=C1C(=O)N(Cc2ccccc2)c2ccccc21 -US04591458,1,CCOC(=O)C(=O)CCCC1CCN(C(=O)OCc2ccccc2)CC1.N[C@H]1COc2ccccc2N(CC(=O)OCc2ccccc2)C1=O>>CCOC(=O)[C@@H](CCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@H]1COc2ccccc2N(CC(=O)OCc2ccccc2)C1=O -US04431822,7,O=[N+]([O-])c1cc(O)c(Cl)cc1F>>Nc1cc(O)c(Cl)cc1F -US20070185079A1,1,CI.O=Cc1c[nH]c2ccc(Br)cc12>>Cn1cc(C=O)c2cc(Br)ccc21 -US20150210697A1,1,CC(C)(C)[Si](C)(C)O[C@@H]1CN(c2cc(C#N)cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)CC[C@H]1N.O=C1COC1>>CC(C)(C)[Si](C)(C)O[C@@H]1CN(c2cc(C#N)cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)CC[C@H]1NC1COC1 -US05059609,3,COc1ccc2c(c1)C(=O)CCO2.O=Cc1ccncc1>>COc1ccc2c(c1)C(=O)C(=Cc1ccncc1)CO2 -US07053086B2,3,CCOC(=O)c1c(C)[nH]c(C=O)c1CCC(=O)O.O=C1Cc2c(cccc2-c2ccncc2)N1>>CCOC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3cccc(-c4ccncc4)c32)c1CCC(=O)O -US05616599,1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CBr)cc1.COCc1nc(C(C)(C)O)c(C(=O)OC)[nH]1>>COCc1nc(C(C)(C)O)c(C(=O)OC)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1 -US05538960,1,CN(C)N.C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@]34C)[C@@]1(O)CC[C@@H]2C=O>>CN(C)/N=C/[C@H]1CC[C@]2(O)[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C -US09073890B2,7,CCCOc1ccc([N+](=O)[O-])c(C(N)=O)c1>>CCCOc1ccc(N)c(C(N)=O)c1 -US07008636B2,2,CCOC(=O)c1cc(-c2cc(C)cc(C)c2)c(OCCO)c(-c2cc(C)cc(C)c2)c1.NCCCCCCCCc1ccccc1>>Cc1cc(C)cc(-c2cc(C(=O)NCCCCCCCCc3ccccc3)cc(-c3cc(C)cc(C)c3)c2OCCO)c1 -US20140066457A1,2,CC[Si](C#CCCO)(CC)CC.Cc1ccc(S(=O)(=O)Cl)cc1>>CC[Si](C#CCCOS(=O)(=O)c1ccc(C)cc1)(CC)CC -US20020025968A1,1,Clc1nc(NCc2ccccc2)c2ccccc2n1.c1c[nH]cn1>>c1ccc(CNc2nc(-n3ccnc3)nc3ccccc23)cc1 -US04029787,1,CN(C1CCCCC1)S(=O)(=O)c1cc(C(=O)O)ccc1Cl.CN1CCNCC1>>CN1CCN(c2ccc(C(=O)O)cc2S(=O)(=O)N(C)C2CCCCC2)CC1 -US20060122234A1,6,COC(=O)c1ccc(-c2nc(C(F)(F)F)c[nH]2)s1>>O=C(O)c1ccc(-c2nc(C(F)(F)F)c[nH]2)s1 -US20060281764A1,2,CC(C)(C)OC(=O)N1CCC(CC(=O)O)C1.CC(C)c1ccc(N)cc1>>CC(C)c1ccc(NC(=O)CC2CCN(C(=O)OC(C)(C)C)C2)cc1 -US20050245592A1,5,CC(C)(C)c1cc(Br)cc(C=O)c1O.COCCl>>COCOc1c(C=O)cc(Br)cc1C(C)(C)C -US06610283B1,1,C1CCNCC1.CCCCCCCCCCBr>>CCCCCCCCCCN1CCCCC1 -US04880809,2,CCCCOc1ccc2cc(C(=O)O)ccc2c1.COc1cc(CN2CCNCC2)cc(OC)c1OC>>CCCCOc1ccc2cc(C(=O)N3CCN(Cc4cc(OC)c(OC)c(OC)c4)CC3)ccc2c1 -US08916555B2,1,CC(C)(C)c1ccc(Nc2n[nH]c(N)c2C(N)=O)cc1.O=Cc1ccc(O)cc1>>CC(C)(C)c1ccc(Nc2n[nH]c(N=Cc3ccc(O)cc3)c2C(N)=O)cc1 -US06057352,1,CC(=O)CCl.Oc1cc(Cl)cc(Cl)c1>>CC(=O)COc1cc(Cl)cc(Cl)c1 -US20140309210A1,1,N#Cc1cccc(CBr)c1.O=[N+]([O-])c1cn[nH]c1>>N#Cc1cccc(Cn2cc([N+](=O)[O-])cn2)c1 -US20090143439A1,7,CC(=O)OCCc1sc(S(=O)(=O)NC(=O)Nc2cc(C(F)(F)F)cc(C)n2)cc1C>>Cc1cc(C(F)(F)F)cc(NC(=O)NS(=O)(=O)c2cc(C)c(CCO)s2)n1 -US20150232492A1,6,COc1ccc2c(c1)CCC(C1(C)COC(=O)N1)C2>>CC1(C2CCc3cc(O)ccc3C2)COC(=O)N1 -US20140303164A1,2,Cc1cc2ncn(CC(=O)O)c2cc1C.Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@@H](N)Cc3cc(F)cc(F)c3)c21>>Cc1cc2ncn(CC(=O)N[C@@H](Cc3cc(F)cc(F)c3)c3nc(C#CC(C)(C)O)ccc3-c3ccc(Cl)c4c(NS(C)(=O)=O)nn(C)c34)c2cc1C -US20130005707A1,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](N)CC1.N#Cc1ccc(Nc2nc3cccc(Br)n3n2)cc1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](Nc2cccc3nc(Nc4ccc(C#N)cc4)nn23)CC1 -US20040106604A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(N)CN>>CC(C)(N)CNC(=O)OC(C)(C)C -US20090005379A1,1,BrCC1CC1.CC(C)N1CCC(Oc2cnc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1>>CC(C)N1CCC(Oc2cnc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3CC2CC2)CC1 -US06387941B1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CC1CCCN1C(=O)OCc1ccccc1>>CCOC(=O)C=C[C@H]1CCCN1C(=O)OCc1ccccc1 -US08440830B2,2,CC(=O)OC(C)=O.Nc1ccc(Br)cc1>>CC(=O)Nc1ccc(Br)cc1 -US20110034469A1,6,C[C@@H](C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1)N(C)C(=O)OC(C)(C)C>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C1CCCCC1 -US20130040930A1,2,CC(C)(c1ccc(C(=O)O)cc1)N1CCCS1(=O)=O.Cc1cnc(N2CCNCC2)c(C#N)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(C(C)(C)N4CCCS4(=O)=O)cc3)CC2)c(C#N)c1 -US07902356B2,1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(NC(=O)c3sc(-c4ccc(Cl)cc4)nc3CCO)ccc21>>CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(N3CCc4nc(-c5ccc(Cl)cc5)sc4C3=O)ccc21 -US20040220248A1,2,C[Si](C)(C)CCO.O=C=Nc1cc([N+](=O)[O-])ccc1F>>C[Si](C)(C)CCOC(=O)Nc1cc([N+](=O)[O-])ccc1F -US07122545B2,8,COc1ccc(N2CCOCC2)c2sc(C(=O)NC3CCN(C(=O)OC(C)(C)C)CCC3O)nc12>>COc1ccc(N2CCOCC2)c2sc(C(=O)NC3CCN(C(=O)OC(C)(C)C)CCC3=O)nc12 -US20130096118A1,2,CS(=O)(=O)Cl.Cc1c(-c2ccc(C(N)=O)c3[nH]c4c(c23)CNCC4)cccc1-n1cnc2ccccc2c1=O>>Cc1c(-c2ccc(C(N)=O)c3[nH]c4c(c23)CN(S(C)(=O)=O)CC4)cccc1-n1cnc2ccccc2c1=O -US20070004705A1,2,CCOC(=O)n1nc(N)c2c1C(C)(C)N(C(=O)OC(C)(C)C)C2.O=C(Cl)c1ccc(F)cc1>>CCOC(=O)n1nc(NC(=O)c2ccc(F)cc2)c2c1C(C)(C)N(C(=O)OC(C)(C)C)C2 -US20040242884A1,7,Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(C=O)c(CN=[N+]=[N-])c21>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(CO)c(CN=[N+]=[N-])c21 -US20150141400A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc(Cl)c(CN2CCNCC2)cc1N>>CCOC(=O)c1cc(Cl)c(CN2CCN(C(=O)OC(C)(C)C)CC2)cc1N -US20100222328A1,2,CC(C)(C)OC(=O)NC[C@@H]1CCCCN1.O=C(O)c1nc(C2CC2)sc1-c1ccccc1F>>CC(C)(C)OC(=O)NC[C@@H]1CCCCN1C(=O)c1nc(C2CC2)sc1-c1ccccc1F -US07276516B2,2,NCc1ccc(C(=O)O)cc1.O=C(O)c1ccc(S(=O)(=O)n2cc(-c3ccccc3)c3ccccc32)cc1>>O=C(O)c1ccc(CNC(=O)c2ccc(S(=O)(=O)n3cc(-c4ccccc4)c4ccccc43)cc2)cc1 -US20130064770A1,1,Fc1ccc(C2(c3ccccc3)OC(CCl)CS2)cc1.NCCCc1ccccc1>>Fc1ccc(C2(c3ccccc3)OC(CNCCCc3ccccc3)CS2)cc1 -US04105666,2,O=C(Cl)c1ccccc1.O=C(NC1CCN(CCCO)CC1)c1ccccc1>>O=C(NC1CCN(CCCOC(=O)c2ccccc2)CC1)c1ccccc1 -US04208517,1,C=[N+]=[N-].O=C(O)/C(=N\O)c1ccccc1>>COC(=O)/C(=N\O)c1ccccc1 -US20030166650A1,2,CC(N)c1cccc(OC(F)(F)F)c1.O=C(O)C=Cc1ccccn1>>CC(NC(=O)C=Cc1ccccn1)c1cccc(OC(F)(F)F)c1 -US05994368,2,CS(=O)(=O)Cl.Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(N)c(C)c4)c3Cl)c2n1>>Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(NS(C)(=O)=O)c(C)c4)c3Cl)c2n1 -US20150175600A1,6,CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCc2ccccc2)CC[C@H]1O>>CC(C)(C)OC(=O)N[C@H]1CNCC[C@H]1O -US20090099184A1,2,NCc1ccc(Cl)cc1Cl.O=C(O)c1ccc(OCC(F)(F)F)nc1>>O=C(NCc1ccc(Cl)cc1Cl)c1ccc(OCC(F)(F)F)nc1 -US06624176B2,1,Cc1ccccc1-c1cc(Cl)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.c1nc[nH]n1>>Cc1ccccc1-c1cc(-n2cncn2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US06562989B2,1,CCCCNCCCC.Cc1cccc(Cl)c1>>CCCCN(CCCC)c1cccc(C)c1 -US20070232615A1,1,CC(C)N1CCNCC1.CN(Cc1cn2c(F)cccc2n1)[C@H]1CCCc2cccnc21>>CC(C)N1CCN(c2cccc3nc(CN(C)[C@H]4CCCc5cccnc54)cn23)CC1 -US20150023913A1,1,CCOC(=O)C(C)(C)Br.NC1CCCCC1>>CCOC(=O)C(C)(C)NC1CCCCC1 -US20150266859A1,2,CCCC(Oc1ccc(-n2cnc(C(F)(F)F)c2)cc1)c1ccc(C(=O)O)cc1.COC(=O)CCN>>CCCC(Oc1ccc(-n2cnc(C(F)(F)F)c2)cc1)c1ccc(C(=O)NCCC(=O)OC)cc1 -US06960575B2,6,CCOC(=O)CN1C(=O)C(C(C)C)N(C(C)=O)C=C1c1ccccc1>>CC(=O)N1C=C(c2ccccc2)N(CC(=O)O)C(=O)C1C(C)C -US05366987,4,C#CCCCCCCCCCCCC.C[Si](C)(C)N=[N+]=[N-]>>CCCCCCCCCCCCc1c[nH]nn1 -US07635715B2,2,CC(C)(C)OC(=O)CN.CCOC(=O)C1=C(O)c2ccccc2C(C)(C#N)C1=O>>CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccccc2C(C)(C#N)C1=O -US08188098B2,6,CCOc1ccc(OCc2ccccc2)c(F)c1>>CCOc1ccc(O)c(F)c1 -US20090075869A1,6,C=CCCCN(C)C(=O)N[C@H](C(=O)OC)C(C)C>>C=CCCCN(C)C(=O)N[C@H](C(=O)O)C(C)C -US05547949,1,CC(C)(C)CN.Clc1cc(Cl)nc(Cl)n1>>CC(C)(C)CNc1nc(Cl)cc(Cl)n1 -US06136823,1,CN.Nc1ccc(F)c(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c1>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)ccc3F)c2c1Cl -US20110313151A1,2,N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1.O=C(O)c1ccc2ncccc2c1>>O=C(N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1)c1ccc2ncccc2c1 -US08324221B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H]1CC2(CN1)C(=O)Nc1ccccc12>>COC(=O)[C@@H]1C[C@]2(CN1C(=O)OC(C)(C)C)C(=O)Nc1ccccc12 -US20020132807A1,1,CCCN1CCNCC1.COc1ccccc1Sc1ccc(-c2ccnc(Cl)c2)cc1C(F)(F)F>>CCCN1CCN(c2cc(-c3ccc(Sc4ccccc4OC)c(C(F)(F)F)c3)ccn2)CC1 -US20100240743A1,1,Cc1cc(C)c(C(CO)c2ccc(C(C)C)cc2)c(O)c1C>>Cc1cc(C)c2c(c1C)OCC2c1ccc(C(C)C)cc1 -US09000006B2,2,CCCCOC(=O)c1ncc2sc(-c3ccc(OC)cc3)cc2c1O.NCC(=O)O>>COc1ccc(-c2cc3c(O)c(C(=O)NCC(=O)O)ncc3s2)cc1 -US20140371283A1,8,O=C(c1ccccc1)C(O)c1cc(F)cc(F)c1>>O=C(C(=O)c1cc(F)cc(F)c1)c1ccccc1 -US05100761,2,Nc1ccc(NNC=O)cc1.O=[N+]([O-])c1cc(S(=O)(=O)Cl)ccc1Cl>>O=CNNc1ccc(NS(=O)(=O)c2ccc(Cl)c([N+](=O)[O-])c2)cc1 -US20100113780A1,3,CC(C)Oc1ccc(B(O)O)cc1.CCCc1nc(C)c(Br)c(=O)n1Cc1ccc(-c2ccccc2C#N)c(F)c1>>CCCc1nc(C)c(-c2ccc(OC(C)C)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)c(F)c1 -US20080090813A1,3,C=Cc1cccc(Br)c1.ICI>>Brc1cccc(C2CC2)c1 -US07285550B2,6,CC(C)(C)OC(=O)N1CCCC1CNc1nc(N)n2nc(-c3ccco3)nc2n1>>Nc1nc(NCC2CCCN2)nc2nc(-c3ccco3)nn12 -US04810713,1,CCOC(=O)c1cc(=O)c2ccc(O)cc2o1.ClCCCBr>>CCOC(=O)c1cc(=O)c2ccc(OCCCCl)cc2o1 -US06297249B1,3,C=CC(=O)OCC.COc1ccc(Br)cn1>>CCOC(=O)C=Cc1ccc(OC)nc1 -US06410539B1,2,COC(=O)[C@@H](N)CCSC.O=C(O)c1ccc(NC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccc(F)cc1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccc(F)cc1 -US06124323,6,COC(=O)c1cc(OCCOCc2ccccc2)ccc1[N+](=O)[O-]>>O=C(O)c1cc(OCCOCc2ccccc2)ccc1[N+](=O)[O-] -US05798311,1,CNC1CN(C(=O)Nc2ccc(C(F)(F)F)cc2)N=C1c1ccc(Cl)cc1.N#CBr>>CN(C#N)C1CN(C(=O)Nc2ccc(C(F)(F)F)cc2)N=C1c1ccc(Cl)cc1 -US08063099B2,6,CCOC(=O)c1cccc2oc(C)nc12>>Cc1nc2c(C(=O)O)cccc2o1 -US05008263,7,Cc1nn(CCO)c(N)c1N=O>>Cc1nn(CCO)c(N)c1N -US20130324530A1,7,COC(=O)C1(C#N)CCOCC1>>N#CC1(CO)CCOCC1 -US20110015407A1,4,CC(C)C(=O)CC(C(=O)c1ccc(F)cc1)c1ccccc1.NCCC1CC(OCc2ccccc2)CC(=O)O1>>CC(C)c1cc(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC1CC(OCc2ccccc2)CC(=O)O1 -US08377976B2,6,CCOC(=O)C1(c2csc(NC)n2)C=CON1>>CNc1nc(C2(C(=O)O)C=CON2)cs1 -US20090325936A1,1,O=C(NC12CC3CC(CC(C3)C1)C2)c1nc(Br)n2ccccc12.Oc1ccccc1>>O=C(NC12CC3CC(CC(C3)C1)C2)c1nc(Oc2ccccc2)n2ccccc12 -US05268386,6,COc1cc(OC)c2c(c1)OC1(CCCCC1)CC2=O>>COc1cc(O)c2c(c1)OC1(CCCCC1)CC2=O -US20080194826A1,6,CCOC(=O)CNC(=O)CC1(CCN2CCC(N(C(=O)c3ccco3)c3ccc(C)cn3)CC2)CCCCC1>>Cc1ccc(N(C(=O)c2ccco2)C2CCN(CCC3(CC(=O)NCC(=O)O)CCCCC3)CC2)nc1 -US20080305169A1,2,COc1ccc(N)c(O)c1.O=C(Cl)CCl>>COc1ccc(NC(=O)CCl)c(O)c1 -US07244725B2,1,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CN.CC(C)Oc1ccc2c(c1)C(Br)COC2(C)C>>CC(C)Oc1ccc2c(c1)C(NC[C@@H](O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)OC(C)(C)C)COC2(C)C -US20100256134A1,2,CC1(C)Cc2cccc(Nc3c(C(=O)N4CCC(c5ccccc5)CC4)cnc4c(C(=O)O)cnn34)c2O1.CCS(N)(=O)=O>>CCS(=O)(=O)NC(=O)c1cnn2c(Nc3cccc4c3OC(C)(C)C4)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12 -US08143424B2,7,COc1c(C)ccc2c1CC(Oc1ccc([N+](=O)[O-])cc1)C2=O>>COc1c(C)ccc2c1CC(Oc1ccc([N+](=O)[O-])cc1)C2 -US20030105351A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(CCC[C@H](N)C(=O)O)[N+](=O)[O-]>>CC(C)(C)OC(=O)N[C@@H](CCCC(C)(C)[N+](=O)[O-])C(=O)O -US20120316195A1,3,C[Mg+].Cn1c(-c2cnccc2C=O)nc2ccc(Cl)cc21>>CC(O)c1ccncc1-c1nc2ccc(Cl)cc2n1C -US04889869,3,CC(C)(C)OC(=O)N[C@H](C=O)CC1CCCCC1.C[C@H](CBr)COCc1ccccc1>>C[C@@H](COCc1ccccc1)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C -US20140378487A1,6,O=C1c2ccccc2C(=O)N1Cc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>NCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1 -US20150232449A1,6,CC(C)(C)OC(=O)Nc1ccc(F)c([C@@]2(C)NC(=S)[C@@](C)(F)CC2(F)F)c1>>C[C@]1(F)CC(F)(F)[C@@](C)(c2cc(N)ccc2F)NC1=S -US20130267546A1,4,CC(=O)CC(C)=O.N=C(N)N>>Cc1cc(C)nc(N)n1 -US20150080396A1,7,C[C@@H](c1ccccc1)N(Cc1ccccc1)[C@H](CC(=O)OC(C)(C)C)c1cccc(CO[Si](C)(C)C(C)(C)C)c1>>C[C@@H](c1ccccc1)N(Cc1ccccc1)[C@H](CCO)c1cccc(CO[Si](C)(C)C(C)(C)C)c1 -US20150018422A1,6,CCOC(=O)CC(c1cc(COc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)n2)ncn1)C1CC1>>COc1ccc(F)c(-c2ccc(OCc3cc(C(CC(=O)O)C4CC4)ncn3)nc2CC(C)(C)C)c1 -US20150119390A1,6,COc1cc(OCc2cccc(-c3ccc(C(C)OC4CCCCO4)cn3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2cccc(-c3ccc(C(C)O)cn3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US08063234B2,2,CCOC(=O)C1CC1C#N.CNOC>>CON(C)C(=O)C1CC1C#N -US20070082907A1,1,COC(=O)CCc1ccc(O)cc1C.Fc1cc(Br)cc(Br)c1>>COC(=O)CCc1ccc(Oc2cc(F)cc(Br)c2)cc1C -US20100292212A1,1,CC(C)CS(=O)(=O)N1CCC2(CCNC2=O)CC1.CC(O)(c1ccc(I)cc1)C(F)(F)F>>CC(C)CS(=O)(=O)N1CCC2(CCN(c3ccc(C(C)(O)C(F)(F)F)cc3)C2=O)CC1 -US07875639B2,6,COC(=O)C12CC3CC(CC(C3)O1)C2>>O=C(O)C12CC3CC(CC(C3)O1)C2 -US20150152108A1,1,CC1(C)OC[C@@H](CO)O1.Nc1cncc(Cl)n1>>CC1(C)OC[C@@H](COc2cncc(N)n2)O1 -US07141561B2,6,COc1ccc(-n2ccn(-c3ccc(Oc4ccccc4)cc3)c2=O)cc1>>O=c1n(-c2ccc(O)cc2)ccn1-c1ccc(Oc2ccccc2)cc1 -US20090227585A1,1,COc1ccccc1CCl.O=C(O)Cc1ccc(O)c(Cl)c1>>COc1ccccc1COc1ccc(CC(=O)O)cc1Cl -US20150011461A1,7,CC(C)(C)OC(=O)C1CC(C)(C)C(=O)N1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)C1CC(C)(C)C(O)N1C(=O)OC(C)(C)C -US04010177,1,CCNCC1CC1.Fc1ccc2c(c1)C(c1ccccc1F)=NCc1nnc(CCl)n1-2>>CCN(Cc1nnc2n1-c1ccc(F)cc1C(c1ccccc1F)=NC2)CC1CC1 -US06716856B1,1,CI.Cc1nn(-c2ccccn2)c2c1C(O)CC(C)(C)C2>>COC1CC(C)(C)Cc2c1c(C)nn2-c1ccccn1 -US06229011B1,6,COC(=O)[C@@H](N)Cc1ccccc1>>N[C@@H](Cc1ccccc1)C(=O)O -US20150018342A1,3,CC[C@@H](NC(=O)c1c(Br)c(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1.C[Sn](C)(C)C>>CC[C@@H](NC(=O)c1c(C)c(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 -US08163737B2,2,CC(C)(C)CCN1C(=O)[C@H](CC(=O)O)SC1c1cc(F)cc(F)c1N1CCN(C(C)(C)C)CC1.O=C1Nc2ccccc2CCN1C1CCNCC1>>CC(C)(C)CCN1C(=O)[C@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)SC1c1cc(F)cc(F)c1N1CCN(C(C)(C)C)CC1 -US05238959,1,CN(C)CCC(O)c1ccccc1.O=[N+]([O-])c1ccc(F)cc1>>CN(C)CCC(Oc1ccc([N+](=O)[O-])cc1)c1ccccc1 -US20140378474A1,2,N=C(N)c1ccc(CN)cc1.O=C(O)c1cnn(Cc2ccc3ccccc3c2)c1>>N=C(N)c1ccc(CNC(=O)c2cnn(Cc3ccc4ccccc4c3)c2)cc1 -US20110213143A1,2,CC(C)(C)OC(=O)NCCC[C@@H](Cc1ncn2c1CCc1ccccc1-2)C(=O)O.CCCCCCCO>>CCCCCCCOC(=O)[C@@H](CCCNC(=O)OC(C)(C)C)Cc1ncn2c1CCc1ccccc1-2 -US20020004511A1,1,Cc1cc2cc(N)ccc2[nH]1.Cn1c(-c2cc3nccc(Cl)c3s2)cnc1C(=O)NCCN1CCCCC1>>Cc1cc2cc(Nc3ccnc4cc(-c5cnc(C(=O)NCCN6CCCCC6)n5C)sc34)ccc2[nH]1 -US20090137548A1,3,C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1I.OB(O)c1cccc(-n2cccn2)c1>>C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1-c1cccc(-n2cccn2)c1 -US20150266848A1,7,CC(C)(C)C(=O)OCC[C@H]1OC2(CCCC2)O[C@@H]1c1ccccc1Cl>>OCC[C@H]1OC2(CCCC2)O[C@@H]1c1ccccc1Cl -US07772183B2,2,CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(O)CN2C1=O.O=C(Cl)c1ccc(F)cc1>>CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(OC(=O)c3ccc(F)cc3)CN2C1=O -US20090209585A1,6,CCOC(=O)C1=CCCCC1S(=O)(=O)N(Cc1cc(C)c(OC(=O)CN(C)C(=O)OC(C)(C)C)c(C)c1)c1ccc(F)cc1Cl>>CCOC(=O)C1=CCCCC1S(=O)(=O)N(Cc1cc(C)c(OC(=O)CNC)c(C)c1)c1ccc(F)cc1Cl -US08338605B2,1,CC(=O)Nc1ccc(Sc2ccc(OCc3ccc(Br)cc3)cc2N)cc1.Cc1ccc2c(Cl)ccnc2n1>>CC(=O)Nc1ccc(Sc2ccc(OCc3ccc(Br)cc3)cc2Nc2ccnc3nc(C)ccc23)cc1 -US20090227566A1,2,CSc1ccc(C(=O)O)c(OCCCNC(=O)OC(C)(C)C)c1.Nc1ccc(F)cc1C(=O)Nc1ccc(Cl)cn1>>CSc1ccc(C(=O)Nc2ccc(F)cc2C(=O)Nc2ccc(Cl)cn2)c(OCCCNC(=O)OC(C)(C)C)c1 -US20130338111A1,1,COc1ccc(Cl)cc1-c1ccnc(Cl)c1.OC1CCC1>>COc1ccc(Cl)cc1-c1ccnc(OC2CCC2)c1 -US04780477,1,CC(C)N(CCN1C(=O)C(=O)c2ccccc21)C(C)C.CNC(=O)NN>>CNC(=O)N/N=C1/C(=O)N(CCN(C(C)C)C(C)C)c2ccccc21 -US20140128385A1,1,CC(C)(C)OC(=O)CBr.CC(C)(C)OC(=O)NC(CN)(c1cc(Br)ccc1F)C(F)F>>CC(C)(C)OC(=O)CNCC(NC(=O)OC(C)(C)C)(c1cc(Br)ccc1F)C(F)F -US08183262B2,1,FC(F)(F)c1cc(-c2ccc(Cl)cc2)nc(Cl)n1.c1cc[nH]c1>>FC(F)(F)c1cc(-c2ccc(Cl)cc2)nc(-n2cccc2)n1 -US06911468B2,6,CCCCCCCc1ccc(CCCn2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)cc1>>CCCCCCCc1ccc(CCCn2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)O)cc2)cc1 -US20150225401A1,7,CC(C)(C)OC(=O)C1(C(=O)O)CCCC1>>CC(C)(C)OC(=O)C1(CO)CCCC1 -US20050032873A1,6,COC(=O)c1ccc(F)c2c1CC(NCc1ccccc1)CC2>>O=C(O)c1ccc(F)c2c1CC(NCc1ccccc1)CC2 -US20050245607A1,2,C#CCOC(C(=O)O)c1ccc(Cl)cc1.COc1cc(-c2ccccc2N)ccc1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>C#CCOC(C(=O)Nc1ccccc1-c1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(OC)c1)c1ccc(Cl)cc1 -US20090286778A1,1,CC(C)(C)OC(=O)Nc1cccc(N)c1.CS(=O)(=O)OCCSc1cccc(Nc2nc(Cl)ncc2Cl)c1>>CC(C)(C)OC(=O)Nc1cccc(NCCSc2cccc(Nc3nc(Cl)ncc3Cl)c2)c1 -US20040192676A1,6,COC(=O)CC1CCCCCC1N1CCN(Cc2ccccc2)CC1>>COC(=O)CC1CCCCCC1N1CCNCC1 -US20090036450A1,6,COC(=O)c1c(-c2ccc(C#N)cc2)noc1C>>Cc1onc(-c2ccc(C#N)cc2)c1C(=O)O -US07772246B2,3,CC(C)n1cc(-c2ccnc(NC[C@H](C)O)n2)c(I)n1.CNc1ncc(B2OC(C)(C)C(C)(C)O2)cc1C>>CNc1ncc(-c2nn(C(C)C)cc2-c2ccnc(NC[C@H](C)O)n2)cc1C -US09150555B2,6,CCOC(=O)c1cnn(-c2ccc(COC)cc2)c1C>>COCc1ccc(-n2ncc(C(=O)O)c2C)cc1 -US09139559B2,6,Cc1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1NC(=O)OC(C)(C)C>>Cc1nc(OCC(=O)N(C)C2CCNCC2)nc(C)c1NC(=O)OC(C)(C)C -US05208247,1,CC(=O)NCc1cccnc1.CCCCCCCCCCCCCCOc1ccc(CBr)cc1>>CCCCCCCCCCCCCCOc1ccc(CN(Cc2cccnc2)C(C)=O)cc1 -US20070282101A1,2,Nc1cc(-c2cc3ccccc3s2)c2[nH]ncc2c1.O=C1COc2ccc(S(=O)(=O)Cl)cc2N1>>O=C1COc2ccc(S(=O)(=O)Nc3cc(-c4cc5ccccc5s4)c4[nH]ncc4c3)cc2N1 -US20090048251A1,2,CN.COC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cscn4)c3)c12>>CNC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cscn4)c3)c12 -US20070066628A1,7,COc1cccc(-c2ccc3c(c2)CCCC3=O)c1>>COc1cccc(-c2ccc3c(c2)CCCC3O)c1 -US20140171414A1,1,CN(C)C.COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2n[nH]c(=O)n2C1c1ccc(C#N)cc1CBr>>COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2n[nH]c(=O)n2C1c1ccc(C#N)cc1C[N+](C)(C)C -US08618107B2,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cc(F)cc1N1CCc2c(sc3c2CCCC3)C1=O.CN1CCN(c2ccc(Nc3cc(Br)cn(C)c3=O)nc2)CC1>>CC(=O)OCc1c(-c2cc(Nc3ccc(N4CCN(C)CC4)cn3)c(=O)n(C)c2)cc(F)cc1N1CCc2c(sc3c2CCCC3)C1=O -US20120165338A1,6,Cc1nc(-c2c(F)cc(Cl)cc2-c2ccc([C@@H](C)NC(=O)C3(NC(=O)OCC4c5ccccc5-c5ccccc54)COC3)c(F)c2)no1>>Cc1nc(-c2c(F)cc(Cl)cc2-c2ccc([C@@H](C)NC(=O)C3(N)COC3)c(F)c2)no1 -US20080058391A1,7,O=C(O)c1cc(Br)ccn1>>OCc1cc(Br)ccn1 -US08592426B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H]1CCc2cc(Br)ccc21>>CC(C)(C)OC(=O)N[C@H]1CCc2cc(Br)ccc21 -US20080004285A1,3,Clc1ccc2ncnc(N3CCOCC3)c2n1.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2ccc3ncnc(N4CCOCC4)c3n2)cc1 -US20120157479A1,7,CC[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1OC(=O)c1ccccc1>>CC[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1O -US20070179142A1,2,NC1CC1.O=C(O)c1ccc(Br)cn1>>O=C(NC1CC1)c1ccc(Br)cn1 -US20090298836A1,7,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)cc1)CN(C(=O)OC(C)(C)C)c1nnc(-c2ccc([N+](=O)[O-])c(O)c2)s1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)cc1)CN(C(=O)OC(C)(C)C)c1nnc(-c2ccc(N)c(O)c2)s1 -US20110257151A1,2,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cc(F)cc(F)c1.NS(=O)(=O)C1CC1>>CC1(C)Cc2cc(C(=O)NS(=O)(=O)C3CC3)ccc2NC1c1cc(F)cc(F)c1 -US06368814B1,1,CCOC(=O)CCCBr.CN(C)CCCC1c2ccccc2CCc2cc(O)ccc21>>CCOC(=O)CCCOc1ccc2c(c1)CCc1ccccc1C2CCCN(C)C -US07524853B2,6,CCCCn1c(-c2cc(OC)c(OC)c(OC)c2Br)nc2sc3c(O)cc(C)cc3c2c1=O>>CCCCn1c(-c2cc(OC)c(OC)c(O)c2Br)nc2sc3c(O)cc(C)cc3c2c1=O -US05372800,2,CCCCC(CC)C(=O)Cl.Oc1c(I)cc(I)cc1I>>CCCCC(CC)C(=O)Oc1c(I)cc(I)cc1I -US20130035358A1,1,COC(=O)c1cc(C(=O)c2ccc(N(C)c3ccc(Cl)cc3)cn2)ccc1Br.C[Sn](C)(C)[Sn](C)(C)C>>COC(=O)c1cc(C(=O)c2ccc(N(C)c3ccc(Cl)cc3)cn2)ccc1[Sn](C)(C)C -US20140288109A1,2,COC(=O)C1(CO)CN(C(=O)OC(C)(C)C)CCO1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)C1(COS(=O)(=O)c2ccc(C)cc2)CN(C(=O)OC(C)(C)C)CCO1 -US08637508B2,1,O=C(CCl)NC(CO)(CO)c1cc(Br)cnc1Cl>>O=C1COCC(CO)(c2cc(Br)cnc2Cl)N1 -US07795254B2,2,CCOC(=O)c1cc(CO[Si](C)(C)C(C)(C)C)on1.NN>>CC(C)(C)[Si](C)(C)OCc1cc(C(=O)NN)no1 -US07696209B2,2,C1CN(C2CCOCC2)CCN1.Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc(C)c1O>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(C3CCOCC3)CC2)cc(C)c1O -US04065563,7,O=[N+]([O-])c1ccc(-c2nc(-c3cccs3)no2)cc1>>Nc1ccc(-c2nc(-c3cccs3)no2)cc1 -US08084620B2,7,Cc1c(Br)cccc1N1C(=O)c2ccncc2C1=O>>Cc1c(Br)cccc1N1Cc2cnccc2C1=O -US07947727B2,2,CCCNCC(O)(CNc1cccc2c1cnn2-c1ccccc1)C(F)(F)F.O=C(O)c1ccccc1Cl>>CCCN(CC(O)(CNc1cccc2c1cnn2-c1ccccc1)C(F)(F)F)C(=O)c1ccccc1Cl -US07754758B2,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)C1.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(F)cc2)C1 -US05183902,1,Brc1ccccn1.CC(c1ccccc1)N1CC(O)C1>>CC(c1ccccc1)N1CC(Oc2ccccn2)C1 -US04426382,2,CCC=CCC(=O)Cl.COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC>>CCC=CCC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 -US05155113,7,O=C(Oc1cc(OC(=O)c2ccccc2)c(Br)cn1)c1ccccc1>>O=C(Oc1cc(O)c(Br)cn1)c1ccccc1 -US20050272784A1,6,COC(=O)C(CSCc1ccccc1)NC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)sc1-c1ccc(-c2ccccc2)cc1>>O=C(N[C@@H](CSCc1ccccc1)C(=O)O)c1nc(-c2ccc(C(F)(F)F)cc2)sc1-c1ccc(-c2ccccc2)cc1 -US07064218B2,1,CCOC(=O)c1ccc2[nH]c(C(=O)OCC)cc2c1.CI>>CCOC(=O)c1ccc2c(c1)cc(C(=O)OCC)n2C -US20090069368A1,6,Cc1c(NC(=O)c2cccc(OCCNC(=O)OC(C)(C)C)c2)c2ccccn2c1C(=O)c1ccc(NC(=O)C(F)(F)F)c(C(=O)OCc2ccccc2)c1>>Cc1c(NC(=O)c2cccc(OCCN)c2)c2ccccn2c1C(=O)c1ccc(NC(=O)C(F)(F)F)c(C(=O)OCc2ccccc2)c1 -US20130225633A1,1,BrCC1CC1.O=S(=O)(c1cccc(Br)c1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(CO)C1>>O=S(=O)(c1cccc(Br)c1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(COCC2CC2)C1 -US20050288343A1,2,COC(=O)CNCc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1.COc1ccc(OC(=O)Cl)cc1>>COC(=O)CN(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)Oc1ccc(OC)cc1 -US05783572,1,COc1nc2cc(Cl)c(Cl)c(CBr)c2nc1OC.c1n[nH]cc1CCCN1CCOCC1>>COc1nc2cc(Cl)c(Cl)c(Cn3cc(CCCN4CCOCC4)cn3)c2nc1OC -US09067898B1,7,C=C(C)c1snc(-c2ccc(CC)cc2)c1C(=O)OCC>>C=C(C)c1snc(-c2ccc(CC)cc2)c1CO -US20140357618A1,6,CC(C)[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C>>CC(C)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C -US20030195204A1,2,CC[C@H](N)c1ccccc1.COc1ccc2c(C(=O)Cl)c(C)c(-c3ccccc3)nc2c1>>CC[C@H](NC(=O)c1c(C)c(-c2ccccc2)nc2cc(OC)ccc12)c1ccccc1 -US08022096B2,1,CC(C)(N)CC(=O)N1CCCC1.N#C[C@@H]1C[C@H](F)CN1C(=O)CBr>>CC(C)(CC(=O)N1CCCC1)NCC(=O)N1C[C@@H](F)C[C@H]1C#N -US20050267095A1,2,NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1.O=S(=O)(Cl)Cc1ccccc1>>O=S(=O)(Cc1ccccc1)NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1 -US20080214562A1,1,CC(C)(C)OC(=O)N1CCNCC1.Nc1cccc(Cl)c1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCN(c2cccc(N)c2[N+](=O)[O-])CC1 -US20100216827A1,3,CCOC(=O)CP(=O)(OCC)OCC.COc1ccc2c(c1)CCC(=O)C2>>CCOC(=O)/C=C1\CCc2cc(OC)ccc2C1 -US20060063784A1,3,CC(C)CC(=O)Nc1cccc(-c2ccnc3c(Br)cnn23)c1.OB(O)c1cc(Cl)cc(Cl)c1>>CC(C)CC(=O)Nc1cccc(-c2ccnc3c(-c4cc(Cl)cc(Cl)c4)cnn23)c1 -US07776897B2,9,NN.O=C(Cl)C1(c2cccs2)CCOCC1>>NNC(=O)C1(c2cccs2)CCOCC1 -US20100160323A1,2,COC(=O)C1CN(C(=O)c2cc(F)ccc2C(F)(F)F)CCN1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>COC(=O)C1CN(C(=O)c2cc(F)ccc2C(F)(F)F)CCN1C(=O)CNC(=O)c1cc(-c2ccccc2)[nH]n1 -US20110263647A1,3,CC(C)(C)OC(=O)N[C@H](CCc1ncc(Br)s1)[C@@H](O[Si](C)(C)C(C)(C)C)c1ccc(C(F)(F)F)cc1.OB(O)c1ccc2cnc(F)cc2c1>>CC(C)(C)OC(=O)N[C@H](CCc1ncc(-c2ccc3cnc(F)cc3c2)s1)[C@@H](O[Si](C)(C)C(C)(C)C)c1ccc(C(F)(F)F)cc1 -US05736487,8,OCc1nc2ccccc2s1>>O=Cc1nc2ccccc2s1 -US20140107078A1,1,CCOC(=O)CBr.Cc1ccc(N)cc1>>CCOC(=O)CNc1ccc(C)cc1 -US20090004185A1,1,Cc1ccc(C(=O)Nc2ccc(CN)cc2)cn1.Cc1ccc2c(Cl)nc(Cl)nc2c1>>Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(C)nc4)cc3)nc(Cl)nc2c1 -US08772510B2,9,BrC(Br)(Br)Br.OCc1nc(-c2ccccc2)nn1-c1ccccc1>>BrCc1nc(-c2ccccc2)nn1-c1ccccc1 -US20100331293A1,1,COc1cncc(-c2ncc(N3CCOCC3)cc2N)c1.Cc1ccnc(-c2nc3c(Cl)cccc3c(Cl)c2C)c1>>COc1cncc(-c2ncc(N3CCOCC3)cc2Nc2c(C)c(-c3cc(C)ccn3)nc3c(Cl)cccc23)c1 -US04978778,1,C=COC(C)=O.CC(=O)O>>CC(=O)OC(C)OC(C)=O -US20050032786A1,6,Cc1cccc2c(=O)nc(-c3cccc(C(=O)OC(C)(C)C)n3)sc12>>Cc1cccc2c(=O)nc(-c3cccc(C(=O)O)n3)sc12 -US20110230518A1,1,CCC1CCCCN1.O=Cc1cc(Br)ccc1F>>CCC1CCCCN1c1ccc(Br)cc1C=O -US20090221653A1,2,CC(C)(C)OC(=O)N(CCCOCCO)CCc1cccc(Cl)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCOCCCN(CCc2cccc(Cl)c2)C(=O)OC(C)(C)C)cc1 -US06677324B1,1,CNCCc1ccc(C)cc1.C[C@]12C[C@H](F)[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCBr)[C@H]3[C@@H]1CC[C@@H]2O>>Cc1ccc(CCN(C)CCCCC[C@@H]2Cc3cc(O)ccc3[C@H]3[C@@H](F)C[C@@]4(C)[C@@H](CC[C@@H]4O)[C@@H]32)cc1 -US06686373B2,6,COc1ccc(-c2cccc3[nH]c4cnn(C)c4c(=O)c23)cc1>>Cn1ncc2[nH]c3cccc(-c4ccc(O)cc4)c3c(=O)c21 -US20060160832A1,1,COC(=O)c1cc2c(Cl)ccnc2cc1OC.Oc1ccc2[nH]ccc2c1>>COC(=O)c1cc2c(Oc3ccc4[nH]ccc4c3)ccnc2cc1OC -US20100216766A1,1,Clc1ccnc2cc(Br)sc12.O=[N+]([O-])c1ccc(O)c(F)c1>>O=[N+]([O-])c1ccc(Oc2ccnc3cc(Br)sc23)c(F)c1 -US07560558B2,1,COc1cc2c(Oc3cc(C)c(C)cc3C(C)=O)ccnc2cc1O.ClCCCBr>>COc1cc2c(Oc3cc(C)c(C)cc3C(C)=O)ccnc2cc1OCCCCl -US20040204427A1,6,CCc1ccc(N2Cc3cnc(Nc4ccc(F)cc4)nc3N([C@H](C)CO[Si](C)(C)C(C)(C)C)C2=O)cc1>>CCc1ccc(N2Cc3cnc(Nc4ccc(F)cc4)nc3N([C@H](C)CO)C2=O)cc1 -US20050234081A1,4,COC(=O)c1cc(S(=O)(=O)c2cc(N)c(N)c(Br)c2)c(SC)s1.O=CO>>COC(=O)c1cc(S(=O)(=O)c2cc(Br)c3nc[nH]c3c2)c(SC)s1 -US20150038437A1,6,COC(=O)c1ccc2nc(N(C)C)oc2c1>>CN(C)c1nc2ccc(C(=O)O)cc2o1 -US08269008B2,2,CCOC(=O)c1ncc2onc(-c3ccccc3)c2c1O.C[C@H](N)C(=O)O>>C[C@H](NC(=O)c1ncc2onc(-c3ccccc3)c2c1O)C(=O)O -US08461330B2,2,COCC(C)N.O=C(O)c1ccc(-c2cnc3ncc(C4(c5ccc6ncccc6c5)CC4)n3c2)cc1F>>COCC(C)NC(=O)c1ccc(-c2cnc3ncc(C4(c5ccc6ncccc6c5)CC4)n3c2)cc1F -US20070105847A1,1,COC(=O)C1(C)OCC(CCCCI)CO1.c1ccc2[nH]ccc2c1>>COC(=O)C1(C)OCC(CCCCn2ccc3ccccc32)CO1 -US20150038438A1,6,COC(=O)c1cc2c(n(C)c1=O)-c1cc3ccn(C)c3cc1C=CC2>>Cn1c2c(cc(C(=O)O)c1=O)CC=Cc1cc3c(ccn3C)cc1-2 -US04857530,1,C#CCN.O=[N+]([O-])c1ccc(F)cc1>>C#CCNc1ccc([N+](=O)[O-])cc1 -US20120172333A1,2,CCOC(=O)c1c(N)cc(Cl)n1-c1ccc(-c2ccsc2)cc1.N#CCC(=O)O>>CCOC(=O)c1c(NC(=O)CC#N)cc(Cl)n1-c1ccc(-c2ccsc2)cc1 -US04631288,4,CC(C)(OCc1ccc(Cl)cc1)C(=O)COc1cccc(Cl)n1.C[S+](C)(C)=O>>CC(C)(OCc1ccc(Cl)cc1)C1(COc2cccc(Cl)n2)CO1 -US05661108,7,CCOC(=O)Nc1cc(NCC(C)C)c([N+](=O)[O-])cc1F>>CCOC(=O)Nc1cc(NCC(C)C)c(N)cc1F -US20110009399A1,1,CC(C)[Si](OCCc1cc(Cl)ccc1[C@@]1(O)CCN(C(=O)OC(C)(C)C)C[C@@H]1O)(C(C)C)C(C)C.COCCCN1C(=O)COc2ccc(CBr)cc21>>COCCCN1C(=O)COc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)CC[C@]3(O)c3ccc(Cl)cc3CCO[Si](C(C)C)(C(C)C)C(C)C)cc21 -US20030087925A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1CC[C@@H](CO)N1>>Cc1ccc(S(=O)(=O)OCC2CCC(=O)N2)cc1 -US20050065164A1,2,CC(C)(C)OC(=O)N1CCC(N)C(C)(C)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCC(NC(=O)OCc2ccccc2)C(C)(C)C1 -US05665719,6,COC(=O)c1sccc1NC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(Nc2ccsc2C(=O)O)CC1 -US05811574,2,C=CC(=O)O.CCCCO>>C=CC(=O)OCCCC -US20040158074A1,3,CS(=O)(=O)c1ccc(-c2cc(F)c(F)cc2Br)cc1.Cc1cc(B(O)O)ccc1F>>Cc1cc(-c2cc(F)c(F)cc2-c2ccc(S(C)(=O)=O)cc2)ccc1F -US20120010315A1,2,C=CC(=O)Cl.OC(COc1ccc2ccccc2c1)COc1ccc2ccccc2c1>>C=CC(=O)OC(COc1ccc2ccccc2c1)COc1ccc2ccccc2c1 -US07314888B1,6,CCOC(=O)CCc1cc(C(=O)c2cc(OCC(C)C)ccc2OCC(C)C)ccc1OCC(C)C>>CC(C)COc1ccc(OCC(C)C)c(C(=O)c2ccc(OCC(C)C)c(CCC(=O)O)c2)c1 -US20140336172A1,6,CCc1c(Br)ccc2c1cnn2C(C)=O>>CCc1c(Br)ccc2[nH]ncc12 -US20140371201A1,3,COc1cc(Cl)c(Br)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21.OB(O)c1cccc(F)c1>>COc1cc(Cl)c(-c2cccc(F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 -US20120264735A1,6,COC(=O)COC(=O)Nc1cccc(Cc2nn(-c3cnn(C)c3)ccc2=O)c1>>Cn1cc(-n2ccc(=O)c(Cc3cccc(NC(=O)OCC(=O)O)c3)n2)cn1 -US06080754,3,Brc1ncccc1OCc1ccccc1.CCCBr>>CCCc1ncccc1OCc1ccccc1 -US20130005707A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1noc2cc(Br)ccc12>>CC(C)(C)OC(=O)Nc1noc2cc(Br)ccc12 -US20110092505A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(O)c1cccc(Br)n1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(Br)n2)CC1 -US20060287362A1,2,CN1CCC[C@@H](O)C1.O=C(Cl)C(=O)c1cccs1>>CN1CCC[C@@H](OC(=O)C(=O)c2cccs2)C1 -US03971819,7,NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1OCC(F)(F)F>>Nc1cc(C(=O)O)cc(S(N)(=O)=O)c1OCC(F)(F)F -US20080305169A1,2,CC(C)(C)[Si](C)(C)OCCCOc1ccccc1N.O=C(Cl)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1>>CC(C)(C)[Si](C)(C)OCCCOc1ccccc1NC(=O)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1 -US20100216813A1,2,CCS(=O)(=O)Cl.N#Cc1ccc(N(Cc2ccccc2Cl)[C@H]2CCNC2)cc1Cl>>CCS(=O)(=O)N1CC[C@H](N(Cc2ccccc2Cl)c2ccc(C#N)c(Cl)c2)C1 -US20040220191A1,6,COC(=O)c1cn(Cc2ccccc2)nn1>>O=C(O)c1cn(Cc2ccccc2)nn1 -US07749530B2,1,COc1ccc(N)cc1O.Cc1cc(C(=O)Nc2ccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)cc2)n(C)n1>>COc1ccc(NC=C2C(=O)Nc3cc(C(=O)c4ccc(NC(=O)c5cc(C)nn5C)cc4)ccc32)cc1O -US06265434B1,3,CCOC(=O)CP(=O)(OCC)OCC.O=CC1CCN(Cc2ccccc2)CC1>>CCOC(=O)C=CC1CCN(Cc2ccccc2)CC1 -US20150018341A1,1,CN(CCO)C(=O)OC(C)(C)C.Oc1ccc(Br)cc1>>CN(CCOc1ccc(Br)cc1)C(=O)OC(C)(C)C -US20100292222A1,1,FC(F)(F)c1nnc2ccc(Cl)nn12.Oc1ccc(C2CCNCC2)cc1>>Oc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US20060276433A1,1,NNc1ccc(-c2cnco2)cc1.O=Cc1ccc(O)cc1>>Oc1ccc(C=NNc2ccc(-c3cnco3)cc2)cc1 -US05567694,1,CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)C(=O)C=C[C@]4(O)[C@@H]3CC[C@@H]2C1.CCOCCl>>CCOCO[C@]12C=CC(=O)[C@@]1(C)CC[C@H]1[C@H]2CC[C@@H]2C[C@@H](OC(C)=O)CC[C@]12C -US20120270203A1,1,C1COCCN1.Cc1cc(NC2CCOCC2)c2[nH]c(C3=N[C@@H](CCO)CO3)cc2c1>>Cc1cc(NC2CCOCC2)c2[nH]c(C3=N[C@@H](CCN4CCOCC4)CO3)cc2c1 -US20140350030A1,8,CC(C)(C)OC(=O)NC12CCCC(CO)(CC1)C2>>CC(C)(C)OC(=O)NC12CCCC(C=O)(CC1)C2 -US06017467,3,C#C[Si](C)(C)C.CCCc1ccc(C#Cc2ccc(Br)c(F)c2)cc1>>CCCc1ccc(C#Cc2ccc(C#C[Si](C)(C)C)c(F)c2)cc1 -US08343993B2,6,CC(C)(F)Cn1c(CCOCc2ccccc2)nc2c(N)nc3cccnc3c21>>CC(C)(F)Cn1c(CCO)nc2c(N)nc3cccnc3c21 -US20100249123A1,1,CC(C)(CO)c1ccc([N+](=O)[O-])cc1.CI>>COCC(C)(C)c1ccc([N+](=O)[O-])cc1 -US20080194617A1,6,O=C(NS(=O)(=O)N1CCOCC1)OCc1ccccc1>>NS(=O)(=O)N1CCOCC1 -US20150191472A1,9,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H]1[C@@H]2O[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)OC[C@H]2N(C(=O)OC(C)(C)C)[C@H]1c1c[nH]c2c(N=[N+]=[N-])ncnc12>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H]1[C@@H]2O[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)OC[C@H]2N(C(=O)OC(C)(C)C)[C@H]1c1c[nH]c2c(N)ncnc12 -US20060223849A1,1,CC[O-].Nc1c(F)c(F)cc(C(=O)O)c1[N+](=O)[O-]>>CCOc1cc(C(=O)O)c([N+](=O)[O-])c(N)c1F -US20050054626A1,2,CC(C)(C)OC(=O)CN.O=C(O)c1cc(C(F)(F)F)ccc1F>>CC(C)(C)OC(=O)CNC(=O)c1cc(C(F)(F)F)ccc1F -US05514800,7,CC(=O)c1nc(-c2ccccc2)[nH]c1C>>Cc1[nH]c(-c2ccccc2)nc1C(C)O -US20060287536A1,1,CCC(CC)(c1ccc(OCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1cc(C)c(C=O)s1.COC(=O)CN>>CCC(CC)(c1ccc(OCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1cc(C)c(CNCC(=O)OC)s1 -US20140128598A1,3,C=CC#N.COc1ccc(Br)cc1OC>>COc1ccc(/C=C/C#N)cc1OC -US04906634,1,O=[N+]([O-])c1ccc(F)cc1.c1ccc(CN2CCNCC2)cc1>>O=[N+]([O-])c1ccc(N2CCN(Cc3ccccc3)CC2)cc1 -US08629157B2,1,CC(C)(C)OC(=O)[C@@H]1CCC(=O)N1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)OC(=O)[C@@H]1CCC(=O)N1c1ccc([N+](=O)[O-])cc1 -US20150182513A1,6,CCC(CCn1ccc(-c2ccccc2)cc1=O)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>CCC(CCn1ccc(-c2ccccc2)cc1=O)(C(=O)NO)S(C)(=O)=O -US08629147B2,2,COC(=O)c1ccc2nc(-c3cc(-c4cccnc4OC)ccc3O)[nH]c2c1.NN>>COc1ncccc1-c1ccc(O)c(-c2nc3ccc(C(=O)NN)cc3[nH]2)c1 -US06159904,1,CCSC1CCSc2c(Cl)cc(C(=O)O)c(C)c21.CCn1nccc1O>>CCSC1CCSc2c(Cl)cc(C(=O)Oc3ccnn3CC)c(C)c21 -US04753933,1,CN(C)CCCS.Nc1ccc2ccc(Cl)nc2n1>>CN(C)CCCSc1ccc2ccc(N)nc2n1 -US20140378487A1,1,COc1cc(CO)ccc1Oc1cccc(C(F)(F)F)c1.COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O>>COc1ccc2c(c1)CCn1c-2cc(OCc2ccc(Oc3cccc(C(F)(F)F)c3)c(OC)c2)nc1=O -US20100184815A1,1,CCCn1c([C@H](C)OCc2ccccc2)n[nH]c1=O.Cc1ccc(CBr)cc1>>CCCn1c([C@H](C)OCc2ccccc2)nn(Cc2ccc(C)cc2)c1=O -US07495015B2,6,CC(C)(C)OC(=O)n1nc(-c2ccccc2Cl)c2ccc(Oc3ccccc3F)cc21>>Fc1ccccc1Oc1ccc2c(-c3ccccc3Cl)n[nH]c2c1 -US20100216813A1,1,FC(F)(F)CCI.N#Cc1ccc(N[C@H]2CCNC2)cc1Cl>>N#Cc1ccc(N[C@H]2CCN(CCC(F)(F)F)C2)cc1Cl -US06706885B2,3,Brc1ccc(Br)nc1.C#CCNC(=O)OCc1ccccc1>>O=C(NCC#Cc1ccc(Br)cn1)OCc1ccccc1 -US20030125383A1,7,CC(=O)Nc1ccc2c(c1)C(C)(C)CCC2(C)C>>CCNc1ccc2c(c1)C(C)(C)CCC2(C)C -US20110015157A1,3,CC(=O)CCN(C(=O)OC(C)(C)C)[C@@H](C)c1ccccc1.[Mg+]c1ccccc1>>C[C@@H](c1ccccc1)N(CCC(C)(O)c1ccccc1)C(=O)OC(C)(C)C -US07902354B2,1,COc1ccc2c(c1)C1=C(SCC3(CCNCC3)O1)C(=O)C2=O.Fc1ccc(CBr)cc1>>COc1ccc2c(c1)C1=C(SCC3(CCN(Cc4ccc(F)cc4)CC3)O1)C(=O)C2=O -US20080108608A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=C1c2ccccc2C(=O)N1CCCBr>>CC(C)(C)OC(=O)N1CCN(CCCN2C(=O)c3ccccc3C2=O)CC1 -US20080015223A1,1,Cn1ncc(Br)c1N.Fc1cc(Br)ccc1-c1ccccc1>>Cn1ncc(Br)c1Nc1ccc(-c2ccccc2)c(F)c1 -US08063071B2,3,Brc1ccc2c(c1)CNC2.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(B4OC(C)(C)C(C)(C)O4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc5c(c4)CNC5)cc23)CC1 -US06469198B2,1,CCCCOc1ccc(C(C)(C)C)cc1C(O)(c1cc(C(C)(C)C)ccc1OCCCC)[C@@H](C)N.O=Cc1ccccc1O>>CCCCOc1ccc(C(C)(C)C)cc1C(O)(c1cc(C(C)(C)C)ccc1OCCCC)[C@@H](C)N=Cc1ccccc1O -US07504410B2,2,C#CCOc1nc(Nc2cc(N)cc(C(=O)OC)c2)ncc1Br.CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O>>C#CCOc1nc(Nc2cc(NC(=O)[C@@H](Cc3ccccc3)NC(=O)OC(C)(C)C)cc(C(=O)OC)c2)ncc1Br -US03952025,2,CC(=O)Cl.c1ccc(-c2cc3c(n2C2CC2)CCCNC3)cc1>>CC(=O)N1CCCc2c(cc(-c3ccccc3)n2C2CC2)C1 -US20150069304A1,1,CCCCC(CC)Cc1cccs1.CCCC[Sn](Cl)(CCCC)CCCC>>CCCCC(CC)Cc1ccc([Sn](CCCC)(CCCC)CCCC)s1 -US20100210570A1,2,NCCc1ccc(Br)cc1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NCCc1ccc(Br)cc1 -US05747518,7,O=[N+]([O-])c1ccsc1-c1ccccc1>>Nc1ccsc1-c1ccccc1 -US20100016318A1,5,C[C@@H]1CN(c2cccc([N+](=O)[O-])c2)C(=O)CN1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C[C@@H]1CN(c2cccc([N+](=O)[O-])c2)C(=O)CN1C(=O)C(F)(F)F -US05728699,1,CS(=O)(=O)Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1.NN>>CS(=O)(=O)Cc1ccc(C(=NN)c2ccc(Cl)cc2)cc1 -US07939549B2,3,O=c1c(Br)cc(-c2ccccn2)cn1-c1ccccc1.[Mg+]C1CCCCC1>>O=c1c(C2CCCCC2)cc(-c2ccccn2)cn1-c1ccccc1 -US20080249305A1,3,CC[Mg+].Fc1ccc(-c2cn3ccnc(Cl)c3n2)c(F)c1>>CCc1nccn2cc(-c3ccc(F)cc3F)nc12 -US20090036495A1,1,C[C@H](NC(=O)c1cc(Cl)cnc1Cl)c1ccc(C(=O)OC(C)(C)C)cc1.Oc1cccc(F)c1>>C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(F)c1)c1ccc(C(=O)OC(C)(C)C)cc1 -US20110212918A1,2,CC(=O)OC(C)=O.Nc1cc(Cl)c(SCc2ccccc2)cn1>>CC(=O)Nc1cc(Cl)c(SCc2ccccc2)cn1 -US20150119390A1,1,COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1.OCc1cccc(-c2cccc(C(F)(F)F)c2)c1>>COc1cc(OCc2cccc(-c3cccc(C(F)(F)F)c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US20090149439A1,2,C1COCCN1.Cc1cc(C(=O)O)ncc1C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(F)cc1>>Cc1cc(C(=O)N2CCOCC2)ncc1C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(F)cc1 -US09156840B2,1,ClCCCBr.Cn1c(=O)[nH]c2ccccc21>>Cn1c(=O)n(CCCCl)c2ccccc21 -US08598154B2,1,C1O[C@@H]2CN[C@H]1C2.COC[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(Cl)nc1)C2>>COC[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3C[C@@H]4C[C@H]3CO4)nc1)C2 -US20120035370A1,2,CS(=O)(=O)c1cc(CN)ccn1.O=C(O)c1cncc2c1cnn2-c1ccc(F)cc1>>CS(=O)(=O)c1cc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1 -US07414060B2,1,Cc1ccc(N)c(C(=O)Nc2nc(C3CC3)cs2)n1.Fc1cc(F)cc(Br)c1>>Cc1ccc(Nc2cc(F)cc(F)c2)c(C(=O)Nc2nc(C3CC3)cs2)n1 -US20030207913A1,3,Clc1ccc(Br)s1.O=Cc1ccc(B(O)O)s1>>O=Cc1ccc(-c2ccc(Cl)s2)s1 -US06391905B1,4,CCCSc1sc(C(=O)OCC)c2c1C(=O)C(Br)CC2.NC(=S)c1ccccc1>>CCCSc1sc(C(=O)OCC)c2c1-c1nc(-c3ccccc3)sc1CC2 -US08178699B2,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.COC(=O)c1sccc1N>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1 -US07989442B2,7,COC(=O)N[C@@H]1CCC(=O)N2c3cc(Br)c(F)cc3Oc3cc(F)ccc3[C@@H]12>>COC(=O)N[C@@H]1CCCN2c3cc(Br)c(F)cc3Oc3cc(F)ccc3[C@@H]12 -US20120157439A1,1,CCCS(=O)(=O)N(Cc1ccc(OC)cc1)c1ccc(F)c(NC(=O)c2csc3c(Cl)ncnc23)c1F.CN>>CCCS(=O)(=O)N(Cc1ccc(OC)cc1)c1ccc(F)c(NC(=O)c2csc3c(NC)ncnc23)c1F -US20080275028A1,8,O=C(NCCCCO)c1cccc(Br)c1>>O=CCCCNC(=O)c1cccc(Br)c1 -US08129406B2,2,N[C@@H]1CCCC[C@H]1C(=O)O.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>O=C(O)[C@@H]1CCCC[C@H]1NS(=O)(=O)c1ccc(-c2ccccc2)cc1 -US20090270360A1,6,C=C1C[C@@H](C(=O)OC)[C@H](C(=O)Nc2ccc(Cl)cc2)C1>>C=C1C[C@@H](C(=O)O)[C@H](C(=O)Nc2ccc(Cl)cc2)C1 -US07589206B2,1,Cc1cc(C(F)(F)F)ccc1N.Cn1ccc2c(Cl)ncc(C(=O)N3CCOCC3)c21>>Cc1cc(C(F)(F)F)ccc1Nc1ncc(C(=O)N2CCOCC2)c2c1ccn2C -US06858651B2,2,CN[C@@H]1CC[C@H](O)CC1.O=C(Cl)OCc1ccccc1>>CN(C(=O)OCc1ccccc1)[C@@H]1CC[C@H](O)CC1 -US20120208827A1,7,O=C(C1CC1)N1CC[C@@H](CNc2cc(C(F)(F)F)ccc2[N+](=O)[O-])C1>>Nc1ccc(C(F)(F)F)cc1NC[C@@H]1CCN(C(=O)C2CC2)C1 -US20030212055A1,1,COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)cnnc2cc1O.OCCOc1ccncc1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)cnnc2cc1OCCOc1ccncc1 -US20150025068A1,2,COC(=O)c1ccc(N)cc1O.O=S(=O)(Cl)c1ccc(F)c(Cl)c1>>COC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1O -US20110009619A1,6,CC(C)(C)OC(=O)NN1CCCCC1=O>>NN1CCCCC1=O -US07407961B2,3,CC(C)n1cc(-c2nc(C(N)=O)c(N)nc2Cl)ccc1=O.COc1ccc(B(O)O)cc1>>COc1ccc(-c2nc(N)c(C(N)=O)nc2-c2ccc(=O)n(C(C)C)c2)cc1 -US20110028467A1,2,COc1c(Br)cc(C(=O)Cl)cc1Br.FC(F)(F)c1cccc(-c2cnc3c(c2)NCCO3)c1>>COc1c(Br)cc(C(=O)N2CCOc3ncc(-c4cccc(C(F)(F)F)c4)cc32)cc1Br -US20030078251A1,2,COC(=O)c1ccccc1N.COc1cccc([C@H]2O[C@H](CC(=O)O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC>>COC(=O)c1ccccc1NC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2N(CC(C)(C)COC(C)=O)C1=O -US20110098296A1,7,Cc1nc(-c2cccc([N+](=O)[O-])c2)c(-c2ccnc(Nc3ccc(OCCN(C)C)c(Cl)c3)n2)s1>>Cc1nc(-c2cccc(N)c2)c(-c2ccnc(Nc3ccc(OCCN(C)C)c(Cl)c3)n2)s1 -US20080292588A1,1,CC(C)(C)OC(=O)NN.CCOC(=O)C=O>>CCOC(=O)C=NNC(=O)OC(C)(C)C -US20150216172A1,9,NO.O=Cc1ccc2ncc(Cl)cc2c1>>ON=Cc1ccc2ncc(Cl)cc2c1 -US20150252038A1,1,CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC2(F)CCNCC2)cc1F.O=Cc1ccc(OC(F)(F)F)c(Cl)c1>>CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC2(F)CCN(Cc3ccc(OC(F)(F)F)c(Cl)c3)CC2)cc1F -US07655679B2,6,CC(C)(C)OC(=O)NCCc1ccc(C#N)cc1>>N#Cc1ccc(CCN)cc1 -US05342846,4,C#Cc1ccccc1.[N-]=[N+]=NC1CCN(Cc2ccccc2)C1>>c1ccc(CN2CCC(n3nncc3-c3ccccc3)C2)cc1 -US20020156079A1,1,Cc1c(C)n(C[C@H]2C[C@@H]2C)c2c(Cl)nncc12.OCc1ccc(F)cc1>>Cc1c(C)n(C[C@H]2C[C@@H]2C)c2c(OCc3ccc(F)cc3)nncc12 -US20040097733A1,1,CC=O.CCOC(=O)c1ccc(Nc2cc3c(cc2C)C(C)(C)CC=C3CC)cc1>>CCOC(=O)c1ccc(N(CC)c2cc3c(cc2C)C(C)(C)CC=C3CC)cc1 -US20050153987A1,2,CN(C)CCN.O=S(=O)(Cl)c1ccc(Cl)nc1>>CN(C)CCNS(=O)(=O)c1ccc(Cl)nc1 -US05457104,9,CCOC(=O)C(C(=O)OCC)C(=O)c1ccc(Cl)nc1Cl>>CCOC(=O)CC(=O)c1ccc(Cl)nc1Cl -US07067534B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.O=C(Cl)c1ccc(Oc2cc(Cl)cc(Cl)c2)[nH]1>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](NC(=O)c3ccc(Oc4cc(Cl)cc(Cl)c4)[nH]3)c3ccccc3)CC2)c1 -US04892873,6,CC(=O)N(C)c1cccc(-c2ccc3nnc(C)n3n2)c1>>CNc1cccc(-c2ccc3nnc(C)n3n2)c1 -US05824691,3,C=O.CNC.COC(=O)c1cccc(-n2cccc2)c1>>COC(=O)c1cccc(-n2cccc2CN(C)C)c1 -US20130240799A1,2,CCCCCCCCCCCCN.O=C(Cl)c1ccc2c(=O)oc(-c3ccccc3)nc2c1>>CCCCCCCCCCCCNC(=O)c1ccc2c(=O)oc(-c3ccccc3)nc2c1 -US07915274B2,1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(OS(C)(=O)=O)C2.Oc1ccccc1F>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(Oc1ccccc1F)C2 -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.Oc1ccc(OC(F)(F)F)cc1>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4ccc(OC(F)(F)F)cc4)ncnc32)CC1 -US05039691,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.c1c[nH]cn1>>c1ccc(C(c2ccccc2)(c2ccccc2)n2ccnc2)cc1 -US09120749B2,1,CCN(CC)C1CCC(N)CC1.O=C(c1cnc2ccc(Br)cc2c1Cl)C1CC1>>CCN(CC)C1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)CC1 -US05102877,7,CC1(C2CN(Cc3ccccc3)C(=O)CO2)OCCO1>>CC1(C2CN(Cc3ccccc3)CCO2)OCCO1 -US06593333B1,2,COCC(=O)Cl.Nc1cc(N2C(=O)c3ccccc3C2=O)c(Cl)cc1F>>COCC(=O)Nc1cc(N2C(=O)c3ccccc3C2=O)c(Cl)cc1F -US07241770B2,1,CC1(C)C2CCC(CCN3CCC4(CC3)C(=O)N(CCCCl)CN4c3ccccc3)C1C2.CN>>CNCCCN1CN(c2ccccc2)C2(CCN(CCC3CCC4CC3C4(C)C)CC2)C1=O -US04992552,2,COC(=O)[C@@H](N)Cc1ccccc1.O=C(O)CNC(=O)OCc1ccccc1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)OCc1ccccc1 -US20100256134A1,2,CS(N)(=O)=O.Cc1ccccc1C1CCN(C(=O)c2cnc3c(C(=O)O)cnn3c2NCc2ccccc2)CC1>>Cc1ccccc1C1CCN(C(=O)c2cnc3c(C(=O)NS(C)(=O)=O)cnn3c2NCc2ccccc2)CC1 -US20140171405A1,3,CN1CCN(c2cc(B3OC(C)(C)C(C)(C)O3)ccn2)CC1.COc1cc(OC)c(F)c(-c2cc3[nH]nc(I)c3cn2)c1F>>COc1cc(OC)c(F)c(-c2cc3[nH]nc(-c4ccnc(N5CCN(C)CC5)c4)c3cn2)c1F -US20070219235A1,6,CCN(CC)c1cc2[nH]c(Nc3cccc(C(=O)OC)c3)nc2cc1C(=O)Nc1ccc2cn[nH]c2c1>>CCN(CC)c1cc2[nH]c(Nc3cccc(C(=O)O)c3)nc2cc1C(=O)Nc1ccc2cn[nH]c2c1 -US20130072499A1,4,Cc1c(N)cccc1C(=O)O.OCC(O)CO>>Cc1c(C(=O)O)ccc2cccnc12 -US04762840,7,CC(C(=O)OC1(C)CCCCC1)c1ccc([N+](=O)[O-])cc1>>CC(C(=O)OC1(C)CCCCC1)c1ccc(N)cc1 -US20080194647A1,2,CNC.O=C(Cl)c1cc(I)ccc1F>>CN(C)C(=O)c1cc(I)ccc1F -US20070149562A1,6,c1ccc(N2CCC3(CC2)OCCO3)nc1>>O=C1CCN(c2ccccn2)CC1 -US20060264460A1,7,N#Cc1cnc2c(Cl)cc([N+](=O)[O-])cc2c1Nc1ccc(F)c(Cl)c1>>N#Cc1cnc2c(Cl)cc(N)cc2c1Nc1ccc(F)c(Cl)c1 -US09045475B2,6,CC(C)(C)OC(=O)N[C@@H]1CCN(CC(F)F)C1>>N[C@@H]1CCN(CC(F)F)C1 -US05141930,4,ON=C1CCSc2sccc21>>O=C1NCCSc2sccc21 -US20120289522A1,9,BrCC1(c2ccc(Br)cc2)CC1.[C-]#N>>N#CCC1(c2ccc(Br)cc2)CC1 -US20110201599A1,1,C[Si](C)(C)CCOCCl.Clc1ncnc2[nH]cc(Br)c12>>C[Si](C)(C)CCOCn1cc(Br)c2c(Cl)ncnc21 -US20140249132A1,2,COc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C#N)c1C1CNC1.CS(=O)(=O)Cl>>COc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C#N)c1C1CN(S(C)(=O)=O)C1 -US20140329803A1,6,CCOC(=O)N1CCCC(N2CCC(C#N)(C(=O)OCC)CC2)CC1>>CCOC(=O)N1CCCC(N2CCC(C#N)(C(=O)O)CC2)CC1 -US20090227570A1,2,CN(C)S(=O)(=O)Cl.COc1cc(C)cc2c1C(Nc1ccc3cc(N)ccc3n1)CC2>>COc1cc(C)cc2c1C(Nc1ccc3cc(NS(=O)(=O)N(C)C)ccc3n1)CC2 -US07550490B2,2,NCc1ccc(C(=O)O)cc1.O=C(O)C=Cc1cccnc1>>O=C(C=Cc1cccnc1)NCc1ccc(C(=O)O)cc1 -US20100056515A1,8,CCC(CC)c1ccc(Cl)c2nc(Oc3c(C)cc(SC)cc3Cl)n(C)c12.O=C(OO)c1cccc(Cl)c1>>CCC(CC)c1ccc(Cl)c2nc(Oc3c(C)cc(S(C)=O)cc3Cl)n(C)c12 -US07579356B2,7,O=[N+]([O-])c1ccc(CNC[C@H]2CCCO2)cc1>>Nc1ccc(CNC[C@H]2CCCO2)cc1 -US20080076774A1,9,Cc1c(N2CCN(C(=O)C(F)(F)F)CC2)cc(C(=O)F)cc1N(CCN1CCCC1)C(=O)C(F)(F)F.[N-]=[N+]=[N-]>>Cc1c(N2CCN(C(=O)C(F)(F)F)CC2)cc(C(=O)N=[N+]=[N-])cc1N(CCN1CCCC1)C(=O)C(F)(F)F -US04608383,7,COC(=O)c1csc(C)c1N>>Cc1scc(CO)c1N -US20100249024A1,7,O=[N+]([O-])c1cc(CO)cc(C(F)(F)F)c1>>Nc1cc(CO)cc(C(F)(F)F)c1 -US20080039476A1,2,CC1NCCc2[nH]ccc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2cc[nH]c2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US04093736,6,CCC(=O)C(CCCCCCc1ccccc1OC)C(=O)CC>>CCC(=O)C(CCCCCCc1ccccc1O)C(=O)CC -US06703392B2,1,BrCC1CC1.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NCc1ccccc1)CC2>>COc1ccc(CC2c3cc(OCC4CC4)c(OC)cc3CCN2CC(=O)NCc2ccccc2)cc1OC -US20090149467A1,1,Clc1nccc(Oc2ccc3[nH]ccc3c2)n1.Ic1ccccc1>>Clc1nccc(Oc2ccc3c(ccn3-c3ccccc3)c2)n1 -US05430041,2,CC(C)(C)NC(=O)[C@@H]1CCCC[C@H]1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O.O=C(O)c1cc(Cl)cc(Cl)c1>>CC(C)(C)NC(=O)[C@@H]1CCCC[C@H]1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1cc(Cl)cc(Cl)c1 -US20150157641A1,2,Nc1cccc([C@]23CN(c4ncc(F)cn4)C[C@H]2CSC(NC(=O)c2ccccc2)=N3)c1.O=C(O)c1ncc(F)cc1F>>O=C(NC1=N[C@@]2(c3cccc(NC(=O)c4ncc(F)cc4F)c3)CN(c3ncc(F)cn3)C[C@H]2CS1)c1ccccc1 -US20040229927A1,2,Nc1ccc(-c2cnc(-c3ccc([N+](=O)[O-])cc3)[nH]2)cc1.O=C(O)C1CCCCC1>>O=C(Nc1ccc(-c2cnc(-c3ccc([N+](=O)[O-])cc3)[nH]2)cc1)C1CCCCC1 -US20120101083A1,1,CCCN.COC(=O)c1cnc(Cl)c(C#N)c1>>CCCNc1ncc(C(=O)OC)cc1C#N -US06013658,8,CN(C(=O)OC(C)(C)C)[C@@H](CO)Cc1ccccc1>>CN(C(=O)OC(C)(C)C)[C@@H](C=O)Cc1ccccc1 -US20100137313A1,6,COC(=O)c1cc(-c2cnc(Nc3cc(C)cc(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)cnc1OC>>COc1ncc(-c2cnc(Nc3cc(C)cc(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)cc1C(=O)O -US20150126449A1,3,Nc1n[nH]c2cccc(Cl)c12.OB(O)c1ccccc1F>>Nc1n[nH]c2cccc(-c3ccccc3F)c12 -US07312358B2,2,COCCOc1ccc(S(=O)(=O)N(CC(=O)OC)c2ccc(C)cc2)cc1.NN>>COCCOc1ccc(S(=O)(=O)N(CC(=O)NN)c2ccc(C)cc2)cc1 -US20080200405A1,1,C1CSCCN1.Clc1nsnc1Cl>>Clc1nsnc1N1CCSCC1 -US06583180B2,3,CCOC(=O)CC[Zn+].Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2cccc(Br)c2)cc1>>CCOC(=O)CCc1cccc(Oc2ccc(CN(Cc3ccccc3)c3cccc(NS(C)(=O)=O)c3C)cc2)c1 -US20030078270A1,3,C#Cc1ccc(C2(N(C)Cc3ccccc3)CC2)cc1.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(C#Cc2ccc(C3(N(C)Cc4ccccc4)CC3)cc2)cc1 -US04812565,1,CN1CC(CCCl)Oc2ncccc2C1=S.CNC>>CN(C)CCC1CN(C)C(=S)c2cccnc2O1 -US20060183736A1,6,COc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(S(C)(=O)=O)cc3)ccc2c1>>CS(=O)(=O)c1ccc(-c2ccc3cc(O)ccc3c2Cc2ccc(OCCN3CCCCC3)cc2)cc1 -US08883782B2,8,OCc1cc(-c2cccnc2F)ccc1F>>O=Cc1cc(-c2cccnc2F)ccc1F -US07655671B2,1,CI.CO[C@@]12CCC(=O)[C@@H]3Oc4c(O)ccc5c4[C@@]31CCN(CCc1ccccc1)[C@@H]2C5>>CO[C@@]12CCC(=O)[C@@H]3Oc4c(O)ccc5c4[C@@]31CC[N@@+](C)(CCc1ccccc1)[C@@H]2C5 -US20050143452A1,9,[N-]=[N+]=NCC1Cc2cccc(-c3ccc(F)cc3)c2O1>>NCC1Cc2cccc(-c3ccc(F)cc3)c2O1 -US07745642B2,3,CNCc1ccccc1.O=C1CCCC1.[C-]#N>>CN(Cc1ccccc1)C1(C#N)CCCC1 -US08299267B2,6,CC(C)c1cc(CNC(=O)OC(C)(C)C)cc(CNS(C)(=O)=O)c1>>CC(C)c1cc(CN)cc(CNS(C)(=O)=O)c1 -US07919506B2,1,COC(c1ccc(C(F)(F)F)cc1CBr)C1(C)CCCCC1.Cn1nnc(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1>>COC(c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1)C1(C)CCCCC1 -US20090099106A1,1,Cc1cc(Cl)nc(N)n1.Nc1ccc(C(=O)O)cc1>>Cc1cc(Nc2ccc(C(=O)O)cc2)nc(N)n1 -US20090131418A1,1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)NN2Cc1ccc(F)cc1.CC(C)COc1ccc(CBr)cc1>>CC(C)COc1ccc(CN2C(=O)CC3(CCN(C(=O)OC(C)(C)C)CC3)N2Cc2ccc(F)cc2)cc1 -US20100029655A1,1,Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F.O=[N+]([O-])c1ccc(-c2cc(CCl)on2)cc1>>O=[N+]([O-])c1ccc(-c2cc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)cc1 -US09090599B2,2,COc1cc(CN)on1.C[C@H](Oc1ncc(C(=O)O)cc1-c1ccc(Cl)cc1)C(F)(F)F>>COc1cc(CNC(=O)c2cnc(O[C@@H](C)C(F)(F)F)c(-c3ccc(Cl)cc3)c2)on1 -US20140364435A1,1,CCO.Clc1nccc2occc12>>CCOc1nccc2occc12 -US20060287356A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COCC#Cc1sc(-c2csc3[nH]c(=O)c(C#N)c(O)c23)cc1Br>>C=Cc1cc(-c2csc3[nH]c(=O)c(C#N)c(O)c23)sc1C#CCOC -US20020173527A1,1,BrCCCc1ccccc1.COC(=O)c1ccc2c(C)c[nH]c2c1>>COC(=O)c1ccc2c(C)cn(CCCc3ccccc3)c2c1 -US20050245518A1,1,BrCCBr.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCCBr)cc1 -US08507483B2,2,Nc1cc(F)ccc1O.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cc(F)ccc1O -US04389416,1,CCOC(=O)CBr.O=[N+]([O-])c1ccc(Oc2ccc(O)c(Cl)c2Cl)cc1>>CCOC(=O)COc1ccc(Oc2ccc([N+](=O)[O-])cc2)c(Cl)c1Cl -US20110183954A1,1,C[C@H](N)c1ccc(Cl)cc1.Cn1cnc(Nc2nc(Cl)nc(Cl)n2)c1>>C[C@H](Nc1nc(Cl)nc(Nc2cn(C)cn2)n1)c1ccc(Cl)cc1 -US20090324581A1,7,COC(=O)c1ccc([N+](=O)[O-])c(C(F)(F)F)c1>>COC(=O)c1ccc(N)c(C(F)(F)F)c1 -US06251911B1,2,CN(C)C(=O)Cl.NCc1ccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1>>CN(C)C(=O)NCc1ccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1 -US20110288085A1,3,CC(C)Cc1ncc(Br)s1.Cc1ccccc1-c1cc(B(O)O)cn2ccnc12>>Cc1ccccc1-c1cc(-c2cnc(CC(C)C)s2)cn2ccnc12 -US20080039459A1,2,CN.O=C(O)c1cc2c(N3CCOCC3)nc(-c3cccc4[nH]ncc34)nc2s1>>CNC(=O)c1cc2c(N3CCOCC3)nc(-c3cccc4[nH]ncc34)nc2s1 -US05889026,1,O=C(NCCCCl)c1ccc(OCc2ccccc2)cc1.OC1(Cc2ccccc2)CCNCC1>>O=C(NCCCN1CCC(O)(Cc2ccccc2)CC1)c1ccc(OCc2ccccc2)cc1 -US20060041164A1,1,COC(=O)Cc1cccc(O)c1.C[C@@H](CO)CBr>>COC(=O)Cc1cccc(OC[C@H](C)CBr)c1 -US20130131106A1,1,CCC(=O)OC[C@H](Cc1cn(C)cn1)[C@H](CC)C(=O)O.Cc1ccc(C=O)cc1OCCI>>CCC(=O)OC[C@H](Cc1cn(C)cn1)[C@H](CC)C(=O)OCCOc1cc(C=O)ccc1C -US07319102B1,3,CON(C)C(=O)c1cc2cnc(SC)nc2n1-c1ccc(F)cc1.Clc1ccccc1CBr>>CSc1ncc2cc(C(=O)Cc3ccccc3Cl)n(-c3ccc(F)cc3)c2n1 -US20050113370A1,6,CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(Nc3ccccc3)cc21>>c1ccc(Nc2ccc3c(-c4ccccc4)n[nH]c3c2)cc1 -US20130324579A1,2,Cc1cccc(-c2ocnc2C(=O)O)c1.Nc1cn[nH]c1>>Cc1cccc(-c2ocnc2C(=O)Nc2cn[nH]c2)c1 -US08907128B2,6,c1ccc(COCC2CCC3(CC2)OCCO3)cc1>>O=C1CCC(COCc2ccccc2)CC1 -US04766241,1,CN(C)C=O.COc1ccc(C(C)(C)C)cc1S(N)(=O)=O>>COc1ccc(C(C)(C)C)cc1S(=O)(=O)N=CN(C)C -US20070244131A1,4,COc1nc(Cl)cc(NCCc2ccc(C(=O)NNC(C)=O)cc2)n1>>COc1nc(Cl)cc(NCCc2ccc(-c3nnc(C)o3)cc2)n1 -US20050234081A1,1,N#CCCCCBr.O=C1NC(=O)c2ccccc21>>N#CCCCCN1C(=O)c2ccccc2C1=O -US20100197676A1,1,NCCCN.O=Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F>>NCCCNCc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F -US20150152063A1,6,CC(C)CN/C(=N/C(=O)c1cccc(OCc2ccccc2)c1)Nc1n[nH]c2cc(F)ccc12>>CC(C)CNC(=NC(=O)c1cccc(O)c1)Nc1n[nH]c2cc(F)ccc12 -US08436023B2,1,CC(C)(C)OC(=O)NC1CCC(=O)CC1.O=C(CNc1n[nH]c2ccc(C(F)(F)F)cc12)NC1CNC1>>CC(C)(C)OC(=O)NC1CCC(N2CC(NC(=O)CNc3n[nH]c4ccc(C(F)(F)F)cc34)C2)CC1 -US20040132798A1,2,CC(C)(C)OC(=O)NCCO.Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>Cc1cc(C)c(S(=O)(=O)OCCNC(=O)OC(C)(C)C)c(C)c1 -US20110166344A1,2,CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1NCc1ccc(C)c(F)c1.CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(CC(=O)O)N2>>CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1N(Cc1ccc(C)c(F)c1)C(=O)CC1=NS(=O)(=O)c2cc(NS(C)(=O)=O)ccc2N1 -US06489487B1,3,COc1nn(C)c(=O)n1Cc1cc(Br)ccc1C.C[Sn](C)(C)c1ccccn1>>COc1nn(C)c(=O)n1Cc1cc(-c2ccccn2)ccc1C -US06900215B2,3,CC1(C)COB(c2ccc(F)c(-c3cccc(C#N)c3)c2)OC1.FC(F)(F)c1ccn2c(Br)cnc2n1>>N#Cc1cccc(-c2cc(-c3cnc4nc(C(F)(F)F)ccn34)ccc2F)c1 -US20100041891A1,6,COCOc1c(I)ccnc1Cl>>Oc1c(I)ccnc1Cl -US04435419,1,C=O.Cc1ccc(C23CNCC2C3)cc1>>Cc1ccc(C23CC2CN(C)C3)cc1 -US05616579,2,NC/C=C\COc1cc(CN2CCCCC2)ccn1.O=C(O)c1cc[nH]c1>>O=C(NC/C=C\COc1cc(CN2CCCCC2)ccn1)c1cc[nH]c1 -US04931444,6,CCCN1C(=O)N(c2ccc(N3CCN(c4ccc(OC)cc4)CC3)cc2)NC1C>>CCCN1C(=O)N(c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)NC1C -US08575204B2,3,CN1CCN(Cc2ccccc2NC(=O)c2ccc(Cl)nc2)CC1.Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)Nc2ccccc2CN2CCN(C)CC2)cn1 -US07635715B2,3,CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2cc(Br)ccc2C(C)(C)C1=O.OB(O)c1ccccc1>>CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2cc(-c3ccccc3)ccc2C(C)(C)C1=O -US20150266837A1,6,CCN(NC(=O)OC(C)(C)C)C(=O)c1nnn[nH]1>>CCN(N)C(=O)c1nnn[nH]1 -US08399676B2,2,CC(C)(C)OC(=O)NC1(C(=O)O)CCN(C(=O)OCc2ccccc2)CC1.CC(C)c1ccc(N)cc1>>CC(C)c1ccc(NC(=O)C2(NC(=O)OC(C)(C)C)CCN(C(=O)OCc3ccccc3)CC2)cc1 -US05679695,1,O=[N+]([O-])c1ccccc1Cl.Sc1ccc(Cl)cc1>>O=[N+]([O-])c1ccccc1Sc1ccc(Cl)cc1 -US20070093505A1,2,CC(C)(C)OC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)O.NCC(O)c1ccccc1>>CC(C)(C)OC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)NCC(O)c1ccccc1 -US03939268,1,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3cccnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3cccnc23)CC1 -US20120295889A1,2,CCOC(CN)OCC.O=C(O)c1ccncc1Nc1ccc(I)cc1F>>CCOC(CNC(=O)c1ccncc1Nc1ccc(I)cc1F)OCC -US20130116263A1,3,COC(=O)Cc1ccc(Br)cc1Cl.OB(O)c1cccnc1F>>COC(=O)Cc1ccc(-c2cccnc2F)cc1Cl -US20100226881A1,7,CCOC(=O)c1cnn2ccc(C(F)(F)F)cc12>>OCc1cnn2ccc(C(F)(F)F)cc12 -US20130310333A1,2,CCc1cccc(N=C=O)c1.CN(CCCN)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21>>CCc1cccc(NC(=O)NCCCN(C)C[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@@H]3OC(C)(C)O[C@@H]32)c1 -US20090054422A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.N#Cc1ccc(OCCO)c(F)c1>>Cc1ccc(S(=O)(=O)OCCOc2ccc(C#N)cc2F)cc1 -US20090270443A1,1,Cc1c(Cl)nc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c1NNC(=O)OC(C)(C)C.c1ccc(CNCc2ccccc2)cc1>>Cc1c(Cl)nc(N(Cc2ccccc2)Cc2ccccc2)c([N+](=O)[O-])c1NNC(=O)OC(C)(C)C -US05457106,1,NCc1ccccn1.OCCCSc1ccncc1>>c1ccc(CNCCCSc2ccncc2)nc1 -US05721103,3,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1.CCC[Mg+]>>CCCC(O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1 -US05461060,1,CCOCCl.O=c1cc[nH]c(=S)[nH]1>>CCOCn1ccc(=O)[nH]c1=S -US20050136444A1,1,CN(CCC#N)c1ccc(C=O)cc1.N=C(N)NN>>CN(CCC#N)c1ccc(C=NNC(=N)N)cc1 -US20090018166A1,2,CCC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCC1=O.Cc1ccc(CS(N)(=O)=O)cc1>>CCC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccc(C)cc3)CC2)nc1CN1CCCC1=O -US05344958,7,Cc1c(C(=O)O)cccc1[N+](=O)[O-]>>Cc1c(N)cccc1C(=O)O -US20150259317A1,1,CC(C)(C)C(=O)OCCl.COC(=O)CCC(=O)[O-]>>COC(=O)CCC(=O)OCOC(=O)C(C)(C)C -US20130231329A1,1,CCCOc1cccc(C(=O)c2nc3ccccc3s2)c1.CN1CCC(N)CC1>>CCCOc1cccc(C(=NC2CCN(C)CC2)c2nc3ccccc3s2)c1 -US08623866B2,2,CNC1CCN(C)C1.Cn1ncc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)O>>CN1CCC(N(C)C(=O)c2c(NC(=O)c3nc(C4CC4)cnc3Nc3cncnc3)cnn2C)C1 -US20080214612A1,3,Brc1sc2cc(OCc3ccccc3)ccc2c1Oc1ccc(OCCN2CCCCC2)cc1.CCS(=O)(=O)c1ccc(B(O)O)cc1>>CCS(=O)(=O)c1ccc(-c2sc3cc(OCc4ccccc4)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C)nn1-c1ccnc2ccccc12>>Cc1cc(N2C[C@H](S(=O)(=O)c3ccccc3C(F)(F)F)C[C@H]2C(=O)O)n(-c2ccnc3ccccc23)n1 -US20090286827A1,1,CCCI.CCc1c[nH]c(-c2cnc(Nc3ccc(Cl)cc3)c(Cl)c2)n1>>CCCn1cc(CC)nc1-c1cnc(Nc2ccc(Cl)cc2)c(Cl)c1 -US06498172B1,2,CC(C)(C)OC(=O)COc1cccc(CNCc2ccc(-c3ncccn3)cc2)c1.Cc1noc(C)c1S(=O)(=O)Cl>>Cc1noc(C)c1S(=O)(=O)N(Cc1ccc(-c2ncccn2)cc1)Cc1cccc(OCC(=O)OC(C)(C)C)c1 -US20110105474A1,3,CN(C)C=O.COC(OC)c1ccc(Br)nc1>>COC(OC)c1ccc(C=O)nc1 -US07287646B2,2,NCC(=O)CCC(=O)O.OCc1ccc(C(F)(F)F)cc1>>NCC(=O)CCC(=O)OCc1ccc(C(F)(F)F)cc1 -US06380204B1,7,Cc1nc(C=Cc2nc3ccc(F)cc3c(=O)n2-c2cccnc2C)cs1>>Cc1nc(CCc2nc3ccc(F)cc3c(=O)n2-c2cccnc2C)cs1 -US20150105317A1,6,C[C@@H]1O[C@@H](OCCNC(=O)CN(CC(=O)NCCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)C(=O)CCCCC(=O)OCc2ccccc2)[C@@H](O)[C@H](O)[C@@H]1O>>C[C@@H]1O[C@@H](OCCNC(=O)CN(CC(=O)NCCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)C(=O)CCCCC(=O)O)[C@@H](O)[C@H](O)[C@@H]1O -US20130252941A1,1,Nc1ccc(Cl)nn1.Nc1nccc2nn(-c3c(Cl)cccc3Cl)cc12>>Nc1ccc(Nc2nccc3nn(-c4c(Cl)cccc4Cl)cc23)nn1 -US04559354,6,COc1ccc(-c2ccc(-c3nc(C(F)(F)F)cn3Cc3ccccc3)o2)cc1>>Oc1ccc(-c2ccc(-c3nc(C(F)(F)F)cn3Cc3ccccc3)o2)cc1 -US20110245247A1,1,Brc1cnccc1-c1ccccc1.CCCCN1Cc2cc(N)ccc2C1=O>>CCCCN1Cc2cc(Nc3cnccc3-c3ccccc3)ccc2C1=O -US20040058965A1,9,Cc1oc(-c2ccccc2)nc1CCC(N)=O>>Cc1oc(-c2ccccc2)nc1CCC#N -US20150087639A1,6,CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)ccc1F>>Nc1cc(N2CCOCC2)ccc1F -US08309546B2,2,C[C@@H](O)C(=O)O.C[C@H]1CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC2CC2)CCN1>>C[C@@H](O)C(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC2CC2)C[C@@H]1C -US20120101134A1,6,CCOC(=O)CCc1cc(F)cc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c1OC>>COc1c(CCC(=O)O)cc(F)cc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 -US08518972B2,3,C1COCCN1.C=O.CCOC(=O)c1ccc2nccn2c1>>CCOC(=O)c1ccc2ncc(CN3CCOCC3)n2c1 -US07915267B2,9,COc1ccc([N+](=O)[O-])c(C(=O)O)c1.N>>COc1ccc([N+](=O)[O-])c(C(N)=O)c1 -US06951881B2,3,CN(C)C=O.c1ccc(-c2cc3ccccc3[nH]2)cc1>>O=Cc1c(-c2ccccc2)[nH]c2ccccc12 -US20030078251A1,7,CCOC(=O)CC(=O)c1ccc([N+](=O)[O-])c(OC)c1>>CCOC(=O)CC(O)c1ccc([N+](=O)[O-])c(OC)c1 -US20090170921A1,7,COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(C#N)cc(OC)c21>>COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(CN)cc(OC)c21 -US05583147,6,CCCCCCSC(C(=O)OC)c1ccc(Cl)c(Cl)c1>>CCCCCCSC(C(=O)O)c1ccc(Cl)c(Cl)c1 -US06407103B2,6,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2C(=O)N1CCC(c2[nH]nc3c2C(=O)c2c(NC(=O)NN4CCOCC4)cccc2-3)CC1>>O=C(Nc1cccc2c1C(=O)c1c-2n[nH]c1C1CCN(C(=O)N2C[C@@H]3C[C@H]2CN3)CC1)NN1CCOCC1 -US20140058098A1,1,COC[C@H](N)C(=O)O.FC(F)(F)Cn1ncnc1-c1cn2c(n1)-c1ccc(Br)cc1OCC2>>COC[C@H](Nc1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2)C(=O)O -US07842713B2,1,CI.CN(C)C(=O)c1ccc(Oc2cc(C(=O)OC(C)(C)C)cc3c2CC(C)(CO)O3)cc1F>>COCC1(C)Cc2c(Oc3ccc(C(=O)N(C)C)c(F)c3)cc(C(=O)OC(C)(C)C)cc2O1 -US20050124664A1,1,O=C(c1ccc(F)cc1)c1ccc([N+](=O)[O-])cc1.c1nc[nH]n1>>O=C(c1ccc(-n2cncn2)cc1)c1ccc([N+](=O)[O-])cc1 -US06365603B1,4,CCN(Cc1cc(Br)ccc1OCC1CC1)c1ccc(C#N)nn1.[N-]=[N+]=[N-]>>CCN(Cc1cc(Br)ccc1OCC1CC1)c1ccc(-c2nnn[nH]2)nn1 -US20030158175A1,2,CCOC(=O)C1CCc2ccc(N)cc2O1.O=CO>>CCOC(=O)C1CCc2ccc(NC=O)cc2O1 -US06395751B1,1,CC1CC(=O)c2cc(C(F)(F)F)ccc2N1C(=O)OCc1ccccc1.NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC1CC(=NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cc(C(F)(F)F)ccc2N1C(=O)OCc1ccccc1 -US20090088457A1,2,Cc1cccc(CNC2CC2)c1C.N#CCC(=O)O>>Cc1cccc(CN(C(=O)CC#N)C2CC2)c1C -US07776897B2,2,Cn1c(-c2ccccc2Cl)nnc1C1(C(=O)O)CCC1.NC12CC3CC(CC(C3)C1)C2>>Cn1c(-c2ccccc2Cl)nnc1C1(C(=O)NC23CC4CC(CC(C4)C2)C3)CCC1 -US08063099B2,2,Cc1nc(C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c(-c2cccc(Cl)c2)s1.O=C(O)c1cnc2sccn12>>Cc1nc(C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2cnc3sccn23)c(-c2cccc(Cl)c2)s1 -US20140343036A1,2,NC1CC(O)C1.Nc1ncc(C(=O)O)c2ccc(-c3cccc(F)c3)nc12>>Nc1ncc(C(=O)N[C@H]2C[C@H](O)C2)c2ccc(-c3cccc(F)c3)nc12 -US08178577B2,2,COC(=O)CCCCCCCN.O=C(O)C=C1c2ccccc2-c2ccccc21>>COC(=O)CCCCCCCNC(=O)C=C1c2ccccc2-c2ccccc21 -US08273769B2,1,CO.CS(=O)(=O)OCc1ccc(Br)c(F)c1>>COCc1ccc(Br)c(F)c1 -US09156827B2,3,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1.O=Cc1n[nH]c2ncccc12>>CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2O/C(=C\c2n[nH]c4ncccc24)C3=O)CC1 -US20140343029A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2C=O)CC1>>COC(=O)/C=C/c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2C)CC1 -US20070249607A1,1,CC(C)(C)OC(=O)N1CCC(CO)(c2cccnc2)CC1.FC(F)(F)c1cc(Br)cc(CBr)c1>>CC(C)(C)OC(=O)N1CCC(COCc2cc(Br)cc(C(F)(F)F)c2)(c2cccnc2)CC1 -US06703392B2,6,COC(=O)CC1(C2CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)C=CC=CC1>>COc1ccc(CC2c3cc(OC)c(OC)cc3CCC2C2(CC(=O)O)C=CC=CC2)cc1OC -US20070105845A1,1,CN.O=C1C(CCCCl)Cc2ccccc2N1c1ccccc1>>CNCCCC1Cc2ccccc2N(c2ccccc2)C1=O -US08329682B2,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN(C)C)CCC2.O=C(CO)Nc1cc2c(cc1F)CC(=O)N2>>Cc1c(/C=C2\C(=O)Nc3cc(NC(=O)CO)c(F)cc32)[nH]c2c1C(=O)N(CCN(C)C)CCC2 -US20130225552A1,1,CC(C)(C(=O)N[C@@H]1C[C@@H](Nc2nc3ccccc3s2)C1)c1cccnc1Cl>>CC1(C)C(=O)N([C@@H]2C[C@@H](Nc3nc4ccccc4s3)C2)c2ncccc21 -US20140243290A1,6,Cc1cc(Nc2nccc(OCc3ccccc3)n2)cc(-c2cnc(C(C)(O)C(F)(F)F)s2)c1>>Cc1cc(Nc2nccc(O)n2)cc(-c2cnc(C(C)(O)C(F)(F)F)s2)c1 -US06800778B1,7,CCOC(=O)C1(C(=O)c2ccc(Cl)cc2Cl)CCCC1>>CCOC(=O)C1(C(O)c2ccc(Cl)cc2Cl)CCCC1 -US20090099169A1,2,CC(C)c1cc2cc(S(C)(=O)=O)cc(CO)c2o1.CS(=O)(=O)Cl>>CC(C)c1cc2cc(S(C)(=O)=O)cc(COS(C)(=O)=O)c2o1 -US05457106,2,CCCCCCCC/C=C\CCCCCCCC(=O)Cl.NCCCSc1ccncc1>>CCCCCCCC/C=C\CCCCCCCC(=O)NCCCSc1ccncc1 -US04704464,2,CNC.O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCc1ccccc1>>CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 -US20080027070A1,6,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(Nc3ncc(NC(=O)c4cc(NC(=O)c5ccc(C#N)cc5)ccc4Cl)cn3)cc2)CC1>>N#Cc1ccc(C(=O)Nc2ccc(Cl)c(C(=O)Nc3cnc(Nc4ccc(S(=O)(=O)C5CCNCC5)cc4)nc3)c2)cc1 -US20060264431A1,1,CNC.COC1=N[C@@](C)(CCBr)C(OC)=N[C@@H]1C(C)C>>COC1=N[C@@](C)(CCN(C)C)C(OC)=N[C@@H]1C(C)C -US20080269293A1,1,Cc1cc(O)n(-c2ccccc2Cl)n1.O=[N+]([O-])c1cccnc1Cl>>Cc1cc(Oc2ncccc2[N+](=O)[O-])n(-c2ccccc2Cl)n1 -US20070066675A1,3,CC1(C)CC(=O)c2ccc(OS(=O)(=O)C(F)(F)F)cc21.N#Cc1ccccc1B(O)O>>CC1(C)CC(=O)c2ccc(-c3ccccc3C#N)cc21 -US20020177606A1,3,C=CCBr.COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1=O>>C=CCC1(O)CCN(C(=O)OC(C)(C)C)CC1C(=O)OC -US20070290610A1,7,Brc1cc2c3c(ccc4cc(Br)cc(c43)C2)c1>>Brc1cc2c3c(c1)Cc1cc(Br)cc(c1-3)CC2 -US20140336177A1,6,CCOC(=O)Cc1ccc(-n2nnnc2C)cn1>>Cc1nnnn1-c1ccc(CC(=O)O)nc1 -US20110263571A1,2,COc1cc(I)c(Cl)cc1C(=O)O.Cc1cnc(N2CCNCC2)c(C)c1>>COc1cc(I)c(Cl)cc1C(=O)N1CCN(c2ncc(C)cc2C)CC1 -US20050143436A1,6,CC(C)(C)OC(=O)[C@@H]1CCCN2C(=O)CC[C@H](NC(=O)c3ccccc3)C(=O)N12>>O=C(N[C@H]1CCC(=O)N2CCC[C@@H](C(=O)O)N2C1=O)c1ccccc1 -US20110077243A1,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COc1ncc(C=O)cc1Br>>CO/C=C/c1cnc(OC)c(Br)c1 -US20120172367A1,2,COC(=O)c1nc(Br)c2cccnc2c1O.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1nc(Br)c2cccnc2c1OS(=O)(=O)c1ccc(C)cc1 -US20070219198A1,1,C[C@@H]1CN(c2ccc(C#N)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(F)c1.c1nc[nH]n1>>C[C@@H]1CN(c2ccc(C#N)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(-n2cncn2)c1 -US05892048,1,CC(C)(C)c1ccc(O)cc1.Cn1nc(-c2c(F)cccc2Cl)nc1CCl>>Cn1nc(-c2c(F)cccc2Cl)nc1COc1ccc(C(C)(C)C)cc1 -US20140275030A1,7,Cc1noc(COC(=O)c2ccccc2)c1-c1ccc2[nH]c(=O)n3c2c1OCC3c1ccccn1>>Cc1noc(CO)c1-c1ccc2[nH]c(=O)n3c2c1OCC3c1ccccn1 -US20100216788A1,6,COc1cccc(C2(C(N)=O)CC2)c1>>NC(=O)C1(c2cccc(O)c2)CC1 -US06878750B2,1,CN.ICCOc1ccc(C2=C(c3ccccc3)CCCc3cc(OC4CCCCO4)ccc32)cc1>>CNCCOc1ccc(C2=C(c3ccccc3)CCCc3cc(OC4CCCCO4)ccc32)cc1 -US08163793B2,1,N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3C(F)(F)F)CN2)CC1.O=Cc1ccccc1>>N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3C(F)(F)F)CN2Cc2ccccc2)CC1 -US20070197512A1,6,COC(=O)CN1C(=S)C(C)(C)Oc2ccccc21>>CC1(C)Oc2ccccc2N(CC(=O)O)C1=S -US06174889B1,4,Nc1ccc([N+](=O)[O-])cc1N.O=C(O)Cc1ccccc1>>O=[N+]([O-])c1ccc2[nH]c(Cc3ccccc3)nc2c1 -US20120142633A1,2,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](N)CC1.Cc1c(C(=O)O)c2nccc(-c3c(OCC4CC4)ccc4c3OCO4)c2n1COCC[Si](C)(C)C>>Cc1c(C(=O)N[C@@H]2CC[C@H](NC(=O)OC(C)(C)C)CC2)c2nccc(-c3c(OCC4CC4)ccc4c3OCO4)c2n1COCC[Si](C)(C)C -US05510379,2,CC(C)c1cc(C(C)C)c(O)c(C(C)C)c1.CCOC(=O)CS(=O)(=O)Cl>>CCOC(=O)CS(=O)(=O)Oc1c(C(C)C)cc(C(C)C)cc1C(C)C -US06307056B1,2,COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(N)c(-c3ccccc3)c21.O=C(Cl)Cc1cccs1>>COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(NC(=O)Cc3cccs3)c(-c3ccccc3)c21 -US20150191452A1,6,COc1ccc(C2CN(C(=O)OC(C)(C)C)C2)cc1>>COc1ccc(C2CNC2)cc1 -US20090324581A1,6,CC(C)Cn1cc(COc2ccc3c(c2)CCN3C(=O)OC(C)(C)C)c(C(F)(F)F)n1>>CC(C)Cn1cc(COc2ccc3c(c2)CCN3)c(C(F)(F)F)n1 -US20070004708A1,2,Nc1cccc(Br)n1.O=C=NCCCl>>O=C(NCCCl)Nc1cccc(Br)n1 -US08748621B2,6,O=c1c(C(F)(F)F)c(OCc2ccccc2)ccn1CC1CC1>>O=c1c(C(F)(F)F)c(O)ccn1CC1CC1 -US06825170B2,3,C#CCO.OB(O)c1ccc(I)cc1>>OCC#Cc1ccc(B(O)O)cc1 -US20040209897A1,1,CNN.O=C1NCCc2[nH]c(-c3ccnc(Cl)c3)cc21>>CN(N)c1cc(-c2cc3c([nH]2)CCNC3=O)ccn1 -US20130267510A1,6,CC1CCOc2cccc(Oc3ccc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)cn3)c21>>CC1CCOc2cccc(Oc3ccc(NC(=O)C(C)(C)N)cn3)c21 -US05679671,2,CCOC(=O)CN1C(=O)C(N)CCc2ccccc21.CC[C@H](C)[C@H](SC(C)=O)C(=O)O>>CCOC(=O)CN1C(=O)C(NC(=O)[C@@H](SC(C)=O)[C@@H](C)CC)CCc2ccccc21 -US20150099719A1,1,N#CC1(NC(=O)[C@@H]2CCCC[C@H]2c2oc(-c3ccc(F)c(F)c3)nc2-c2ccc(Br)cc2)CC1.O=S1(=O)CCNCC1>>N#CC1(NC(=O)[C@@H]2CCCC[C@H]2c2oc(-c3ccc(F)c(F)c3)nc2-c2ccc(N3CCS(=O)(=O)CC3)cc2)CC1 -US07026508B2,6,COc1ccc(C(CN(C)C)C2(O)CCCCC2)cc1>>CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1 -US08318759B2,7,COC(=O)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)c(Cl)c1>>OC[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)c(Cl)c1 -US07605176B2,2,CCN(CC)CCOc1ccc(N)cc1Cl.O=C(O)C#Cc1ccc(-c2ccccc2)cc1>>CCN(CC)CCOc1ccc(NC(=O)C#Cc2ccc(-c3ccccc3)cc2)cc1Cl -US07276516B2,2,CO.O=C(Cl)c1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1ccc(S(=O)(=O)Cl)cc1 -US05006522,1,C#CCBr.Cc1scc2c1Nc1ccccc1NC2=O>>C#CCN1c2ccccc2NC(=O)c2csc(C)c21 -US20080004271A1,1,Fc1cc(Br)ccc1Br.OCCO>>OCCOc1cc(Br)ccc1Br -US20110256549A1,6,O=C1c2ccccc2C(=O)N1CCCCOc1cc(Br)cc(Br)c1>>NCCCCOc1cc(Br)cc(Br)c1 -US07572809B2,1,CC(=O)Nc1ccc(O)cc1.COc1cccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc12>>COc1cccc2c(Oc3ccc(NC(C)=O)cc3)nc(Nc3cc(C)[nH]n3)cc12 -US20120270865A2,2,CCC(CC)C(Nc1ccc(C(=O)O)cc1)c1oc2ccc(OC)cc2c1C.CCOC(=O)CCNC>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(OC)cc3c2C)C(CC)CC)cc1 -US07964591B2,2,O=C(Cl)c1cc(F)ccc1C(F)(F)F.O=C(NCCC1CC1)c1ccc(N2CCNCC2)nn1>>O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3cc(F)ccc3C(F)(F)F)CC2)nn1 -US20120277237A1,3,Brc1ccccn1.C#CCCc1nc2c(F)cccc2s1>>Fc1cccc2sc(CCC#Cc3ccccn3)nc12 -US05495025,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1N[C@@H](Cc2ccccc2)[C@@H](CO)O1>>Cc1ccc(S(=O)(=O)OC[C@H]2OC(=O)N[C@H]2Cc2ccccc2)cc1 -US04260547,6,COc1ccc(Cl)c2ccccc12>>Oc1ccc(Cl)c2ccccc12 -US20090156578A1,3,C=CC(=O)N(C)Cc1cc2ccccc2n1C.Nc1cc(=O)[nH]c2ncc(Br)cc12>>CN(Cc1cc2ccccc2n1C)C(=O)C=Cc1cnc2[nH]c(=O)cc(N)c2c1 -US20040259912A1,2,COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccc(C(F)(F)F)cc1.COc1ccc(N=C=O)cc1OC>>COC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OC(c1ccccc1)c1ccc(C(F)(F)F)cc1 -US05998415,6,CC(c1ccccc1)N1CCN(C(=O)OC(C)(C)C)CC1=O>>CC(c1ccccc1)N1CCNCC1=O -US05807860,1,BrCCCBr.O=[N+]([O-])c1c(O)ccc2c1CCCC2>>O=[N+]([O-])c1c(OCCCBr)ccc2c1CCCC2 -US20050096380A1,8,CCOc1cc2c(cc1C(O)CC)C(C(C)(C)C)=CCC2(C)C>>CCOc1cc2c(cc1C(=O)CC)C(C(C)(C)C)=CCC2(C)C -US20100105651A1,1,CC(C)(C)OC(=O)N1CC(N)C1.O=C1CCc2cc(F)ccc21>>CC(C)(C)OC(=O)N1CC(NC2CCc3cc(F)ccc32)C1 -US20130005710A1,3,CN(C)c1ccc(B(O)O)cc1.COc1ccc(N)c(Br)n1>>COc1ccc(N)c(-c2ccc(N(C)C)cc2)n1 -US20110092476A1,2,CC(=O)OCCn1ccc2c(N)c(Cl)ccc2c1=O.O=C(O)Cc1ccc(F)c(C(F)(F)F)c1>>CC(=O)OCCn1ccc2c(NC(=O)Cc3ccc(F)c(C(F)(F)F)c3)c(Cl)ccc2c1=O -US04059602,7,CCCCCC(O)CCCC(CCCCCCC(=O)O)(C(C)=O)c1ccc(Cl)c(Cl)c1>>CCCCCC(O)CCCC(CCCCCCCO)(C(C)=O)c1ccc(Cl)c(Cl)c1 -US20060148858A1,3,CCCC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCCC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1/C=C/C(=O)OCC -US05231107,2,CON=CC1=CCCNC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CON=CC1=CCCN(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1 -US05962682,2,COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(C(=O)O)cc2OCC(O)CO)c1.Nc1ccccc1>>COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(C(=O)Nc3ccccc3)cc2OCC(O)CO)c1 -US20060148858A1,7,CCOC(=O)/C=C/c1cn(Cc2ccccc2)nc1C(C)C>>CCOC(=O)CCc1cn(Cc2ccccc2)nc1C(C)C -US20120208809A1,3,C[Sn](C)(C)c1cc(Cl)ncc1Cl.Nc1ncc(F)cc1I>>Nc1ncc(F)cc1-c1cc(Cl)ncc1Cl -US06706725B1,6,CCC1(c2ccc(COc3ccc(CO)c(CO)c3)s2)OCCO1>>CCC(=O)c1ccc(COc2ccc(CO)c(CO)c2)s1 -US20030181744A1,2,CCCCCCCCCCCCCCCCCCCCCC(=O)O.OCCOc1ccccc1>>CCCCCCCCCCCCCCCCCCCCCC(=O)OCCOc1ccccc1 -US20110263571A1,2,Cc1ccc(N2CCNCC2)c(C)c1.O=C(O)c1ccc(Br)cc1F>>Cc1ccc(N2CCN(C(=O)c3ccc(Br)cc3F)CC2)c(C)c1 -US20040127526A1,2,CCNc1c(C)nn(C)c1C.Cc1ccc(Cl)cc1N=C=S>>CCN(C(=S)Nc1cc(Cl)ccc1C)c1c(C)nn(C)c1C -US08470843B2,7,CCOC(=O)C1(CCOC)CCN(Cc2ccccc2)CC1=O>>CCOC(=O)C1(CCOC)CCN(Cc2ccccc2)CC1O -US20140163012A1,1,CC(C)(C)OC(=O)N1CCc2oc3cc(Br)ccc3c2C1.O=c1cc(OCc2ccc(F)cn2)cn[nH]1>>CC(C)(C)OC(=O)N1CCc2oc3cc(-n4ncc(OCc5ccc(F)cn5)cc4=O)ccc3c2C1 -US20040157886A1,2,Cc1ccc(OC2CCNCC2)cc1.O=C(Cl)CCl>>Cc1ccc(OC2CCN(C(=O)CCl)CC2)cc1 -US06451819B2,6,O=S(=O)(c1ccc(O)cc1)C1CCN(CCCCc2cccc(OCc3ccccc3)c2)C1>>O=S(=O)(c1ccc(O)cc1)C1CCN(CCCCc2cccc(O)c2)C1 -US07928103B2,1,O=Cc1ccc(Cl)nc1.c1ccc([C@H]2CNCCO2)cc1>>Clc1ccc(CN2CCO[C@@H](c3ccccc3)C2)cn1 -US08765730B2,9,Cc1cc(C(=O)C[C@H](c2ccc(CC(=O)O)cc2)c2ccc(Cl)cc2C)ccn1.NO>>Cc1cc(/C(C[C@H](c2ccc(CC(=O)O)cc2)c2ccc(Cl)cc2C)=N/O)ccn1 -US20100261772A1,7,CCOC(=O)COc1cc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccccc2)ccc1C>>Cc1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccccc2)cc1OCCO -US08361996B2,9,CC(=O)O[C@H]1CC[C@@]2(C)C(=CC(=O)[C@H]3[C@@H]4CC[C@H](OC(C)=O)[C@@]4(C)CC[C@@H]32)C1.NO>>CC(=O)O[C@H]1CC[C@@]2(C)C(=CC(=NO)[C@H]3[C@@H]4CC[C@H](OC(C)=O)[C@@]4(C)CC[C@@H]32)C1 -US20040229858A1,5,COC(=O)c1ccc(OC(C)(C)CN)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(OC(C)(C)CNC(=O)C(F)(F)F)cc1 -US08124809B2,3,Cc1ccc(Br)cc1.[Mg+]c1ccccc1>>Cc1ccc(-c2ccccc2)cc1 -US06521620B1,9,Fc1ccc2c(Nc3cccc(Br)c3)ncnc2n1.N>>Nc1ccc2c(Nc3cccc(Br)c3)ncnc2n1 -US20120004164A1,6,COC(=O)c1ccc(CN2CCN(c3nc(C)cs3)C2=O)cc1>>Cc1csc(N2CCN(Cc3ccc(C(=O)O)cc3)C2=O)n1 -US20070197512A1,2,CCOC(=O)/C=C/C(=O)Cl.Cc1ccc2c(c1)NCC(C(C)C)O2>>CCOC(=O)/C=C/C(=O)N1CC(C(C)C)Oc2ccc(C)cc21 -US20110275797A1,6,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(-c2cncnc2)ccc1O>>O=C(Nc1cc(-c2ccccc2)ccc1C(=O)O)c1cc(-c2cncnc2)ccc1O -US03966811,2,COCc1ccc(C)c(NCC=O)c1.O=C(Cl)CCl>>COCc1ccc(C)c(N(CC=O)C(=O)CCl)c1 -US20040229874A1,7,CN1CCN(c2ccccc2-c2ccc(C=O)cc2)CC1>>CN1CCN(c2ccccc2-c2ccc(CO)cc2)CC1 -US20140011777A1,6,COCCc1nc2c(N)nc3ccccc3c2n1CC1(O)CCOCC1>>Nc1nc2ccccc2c2c1nc(CCO)n2CC1(O)CCOCC1 -US20080249318A1,2,Cc1ccc(Nc2c(F)cc(F)c(F)c2F)cc1.O=C(Cl)CCl>>Cc1ccc(N(C(=O)CCl)c2c(F)cc(F)c(F)c2F)cc1 -US20110166169A1,1,CC(N)=O.COC(=O)c1cccc2c1c1ccccc1n2-c1ccc(C#N)c(Br)c1>>COC(=O)c1cccc2c1c1ccccc1n2-c1ccc(C#N)c(NC(C)=O)c1 -US08492378B2,3,COC(=O)c1ccc2occ(Br)c2c1.OB(O)c1ccc(OC(F)(F)F)cc1>>COC(=O)c1ccc2occ(-c3ccc(OC(F)(F)F)cc3)c2c1 -US20130196982A1,3,CC1(C)OB(c2ccc(NC(=O)Nc3ccncc3)cc2)OC1(C)C.C[C@H]1COCCN1c1ccnc(Cl)n1>>C[C@H]1COCCN1c1ccnc(-c2ccc(NC(=O)Nc3ccncc3)cc2)n1 -US20130310333A1,1,CC(C)I.CC1(C)O[C@@H]2[C@H](O1)[C@@H](CN)O[C@H]2n1cnc2cncnc21>>CC(C)NC[C@H]1O[C@@H](n2cnc3cncnc32)[C@@H]2OC(C)(C)O[C@@H]21 -US20070123504A1,1,CI.O=[N+]([O-])c1ccc(N2CCC(O)C2)nc1>>COC1CCN(c2ccc([N+](=O)[O-])cn2)C1 -US05541229,6,CCCCc1nc2cc(NC=O)ccc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2cc(NC=O)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US07951805B2,1,CCCCCNC(=O)c1ccc(Cl)nn1.O=C1N(C2CCNCC2)c2ccccc2C1(F)F>>CCCCCNC(=O)c1ccc(N2CCC(N3C(=O)C(F)(F)c4ccccc43)CC2)nn1 -US06632836B1,6,C#COc1ccccc1C(=O)NCC1(c2ccccc2)CCC(C(=O)OC)CC1>>C#COc1ccccc1C(=O)NCC1(c2ccccc2)CCC(C(=O)O)CC1 -US20150023990A1,2,CC(=O)Cl.CCOCc1nc2c(N)nc3cc(OCCCCCCN)ccc3c2n1CC(C)(C)NC(=O)NC(C)C>>CCOCc1nc2c(N)nc3cc(OCCCCCCNC(C)=O)ccc3c2n1CC(C)(C)NC(=O)NC(C)C -US20140290745A1,3,C#Cc1ccccc1.COc1ccc(I)cc1>>COc1ccc(C#Cc2ccccc2)cc1 -US20130131018A1,5,COCCl.O=Cc1cccc(O)c1O>>COCOc1c(O)cccc1C=O -US07008636B2,6,COC(=O)c1ccc(OCCOc2c(-c3cccc(C(F)(F)F)c3)cc(C(=O)NCCCCCCCCc3ccccc3)cc2-c2cccc(C(F)(F)F)c2)cc1O>>O=C(NCCCCCCCCc1ccccc1)c1cc(-c2cccc(C(F)(F)F)c2)c(OCCOc2ccc(C(=O)O)c(O)c2)c(-c2cccc(C(F)(F)F)c2)c1 -US09102625B2,2,CC(=O)N1CCC[C@@H]1C(=O)O.NC(=O)c1cnc(Nc2ccc(C3CCNCC3)cc2)cc1NCc1cccc(F)c1F>>CC(=O)N1CCC[C@@H]1C(=O)N1CCC(c2ccc(Nc3cc(NCc4cccc(F)c4F)c(C(N)=O)cn3)cc2)CC1 -US20100120760A1,3,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(Br)c3c(c12)CC(C)O3.Cc1noc(C)c1B(O)O>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(-c3c(C)noc3C)c3c(c12)CC(C)O3 -US20100152169A1,2,CCN1CCN(c2cc(C#N)c3ncn(-c4cc(C(=O)O)ccc4C)c(=O)c3c2)CC1.Nc1ccon1>>CCN1CCN(c2cc(C#N)c3ncn(-c4cc(C(=O)Nc5ccon5)ccc4C)c(=O)c3c2)CC1 -US20150148340A1,1,CCOC(=O)c1cn(-c2ccc3c(c2)sc(=O)n3C)c(=O)[nH]c1=O.COc1cccc2c1CCC2O>>CCOC(=O)c1cn(-c2ccc3c(c2)sc(=O)n3C)c(=O)n(C2CCc3c(OC)cccc32)c1=O -US05550240,1,CC(C)(C)CN.CC(C)(C)Nc1cc(Cl)nc(Cl)n1>>CC(C)(C)CNc1nc(Cl)cc(NC(C)(C)C)n1 -US20130217665A1,2,CCOC(=O)N1CCC(N2CCC2C(=O)[O-])CC1.N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3cccc(C(F)(F)F)c3)CN2)CC1>>CCOC(=O)N1CCC(N2CCC2C(=O)N2C[C@H](S(=O)(=O)c3cccc(C(F)(F)F)c3)C[C@H]2C(=O)NC2(C#N)CC2)CC1 -US20150072969A1,1,BrCc1ccc(-c2ccccc2)cc1.CCOC(=O)CC1(c2ccc(O)cc2)COC1>>CCOC(=O)CC1(c2ccc(OCc3ccc(-c4ccccc4)cc3)cc2)COC1 -US20130065925A1,1,C[C@@H]1CN(Cc2c(Cl)cccc2C(F)(F)F)C[C@]1(CC(=O)O)C(=O)NC1CCNCC1.O=CC1=CCCCC1>>C[C@@H]1CN(Cc2c(Cl)cccc2C(F)(F)F)C[C@]1(CC(=O)O)C(=O)NC1CCN(CC2=CCCCC2)CC1 -US08802684B2,1,CCCCOc1nc(N)c2nc(OC)[nH]c2n1.O=C(OCc1ccccc1)N1CCCC(CCCBr)C1>>CCCCOc1nc(N)c2nc(OC)n(CCCC3CCCN(C(=O)OCc4ccccc4)C3)c2n1 -US08269002B2,1,Fc1cccc(CSc2nc(Cl)cc(Cl)n2)c1F.OC1COC(c2ccccc2)OC1>>Fc1cccc(CSc2nc(Cl)cc(OC3COC(c4ccccc4)OC3)n2)c1F -US05994378,6,COC(=O)c1ccc2c(c1)c(C#N)cn2Cc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1>>CC(C)(C)c1csc(-c2cc3cc(Cn4cc(C#N)c5cc(C(=O)O)ccc54)ccc3o2)n1 -US07947727B2,2,CCCNCC(O)(CNc1cc(C)cc2c1cnn2-c1ccc(F)cc1)C(F)(F)F.Cc1ccccc1C(=O)O>>CCCN(CC(O)(CNc1cc(C)cc2c1cnn2-c1ccc(F)cc1)C(F)(F)F)C(=O)c1ccccc1C -US05478844,6,CC(=O)Nc1c(C)cc(OC(C)=O)c(C)c1C>>CC(=O)Nc1c(C)cc(O)c(C)c1C -US05783575,1,CC(=O)c1c(Cl)[nH]c2ccccc12.CI>>CC(=O)c1c(Cl)n(C)c2ccccc12 -US08318718B2,1,Clc1ncccc1-c1ccncc1.Nc1ccc(O)cc1>>Nc1ccc(Oc2ncccc2-c2ccncc2)cc1 -US06197959B1,6,COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)N(CCCN)CCC3)cc1>>COc1ccccc1COCCCOc1ccc([C@H]2CCNC[C@@H]2OCc2ccc3c(c2)N(CCCN)CCC3)cc1 -US20120107248A1,7,CC(C)(C)OC(=O)NCCCCCOc1ccc(N)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)NCCCCCOc1ccc(N)c(N)c1 -US20040176405A1,6,Cc1onc2c1c(=O)n(C1CCCC(NC(=O)C(NC(=O)OC(C)(C)C)c3ccccc3)C1)c1cccc(Cl)c21>>Cc1onc2c1c(=O)n(C1CCCC(NC(=O)C(N)c3ccccc3)C1)c1cccc(Cl)c21 -US05643793,6,CCCC(O)CC(=O)OCC>>CCCC(O)CC(=O)O -US20120277224A1,6,CC(=O)Nc1nn2c(=O)cc(-c3ccc4c(c3)nnn4C(C)=O)[nH]c2c1-c1ccccn1>>CC(=O)Nc1nn2c(=O)cc(-c3ccc4[nH]nnc4c3)[nH]c2c1-c1ccccn1 -US07067517B2,2,C1CC(CNCC2CC2)CCN1.O=C(Cl)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1>>O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(CNCC2CC2)CC1 -US05977374,1,CC(=O)CBr.COC(=O)Cc1ccccc1O>>COC(=O)Cc1ccccc1OCC(C)=O -US20130040930A1,1,N#Cc1cc(Br)ccc1C(=O)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1.O=S1(=O)CCCN1>>N#Cc1cc(N2CCCS2(=O)=O)ccc1C(=O)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1 -US20140213549A9,6,COc1ccc(COC2CC(C)(C)Cc3nc(C4CCN(c5ncccn5)CC4)c(C(F)c4ccc(C(F)(F)F)cc4)c(C4CCC(F)(F)CC4)c32)cc1>>CC1(C)Cc2nc(C3CCN(c4ncccn4)CC3)c(C(F)c3ccc(C(F)(F)F)cc3)c(C3CCC(F)(F)CC3)c2C(O)C1 -US04386088,2,CC(=O)Cl.CC(C)(C)C(=O)C(C(O)C(Cl)(Cl)Cl)n1cncn1>>CC(=O)OC(C(C(=O)C(C)(C)C)n1cncn1)C(Cl)(Cl)Cl -US08735584B2,1,Cc1ccc(N)cc1F.O=c1[nH]c2ncccc2c2cc(Cl)ccc12>>Cc1ccc(Nc2ccc3c(=O)[nH]c4ncccc4c3c2)cc1F -US05958944,6,C[C@@H](NC(=O)OCc1ccccc1)c1ccc(C(=O)Nc2ccnc3[nH]ccc23)cc1>>C[C@@H](N)c1ccc(C(=O)Nc2ccnc3[nH]ccc23)cc1 -US20130165440A1,1,CC(C)(C)OC(=O)Nc1cc([N+](=O)[O-])cc(C(F)(F)F)c1.CN(C)CCCCl>>CN(C)CCCN(C(=O)OC(C)(C)C)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1 -US06900215B2,3,CC1(C)OB(c2ccc(F)c(-c3ccccc3C#N)c2)OC1(C)C.FC(F)(F)c1ccn2c(Br)cnc2n1>>N#Cc1ccccc1-c1cc(-c2cnc3nc(C(F)(F)F)ccn23)ccc1F -US04128564,6,CS(=O)(=O)C(CCCCCCC(=O)O)CCCC(COc1ccc(F)cc1)OCc1ccccc1>>CS(=O)(=O)C(CCCCCCC(=O)O)CCCC(O)COc1ccc(F)cc1 -US09035063B2,7,CCN1CCN(C(=O)c2ccc(N)cc2C(F)(F)F)CC1>>CCN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1 -US20060084690A1,2,Nc1ccc2ncccc2c1.O=C(O)CCc1cnoc1-c1ccccc1>>O=C(CCc1cnoc1-c1ccccc1)Nc1ccc2ncccc2c1 -US05015659,6,CC(C)(C)OC(=O)C(NCC(N)=O)c1cccs1>>NC(=O)CNC(C(=O)O)c1cccs1 -US07696240B2,2,CNC.O=C(O)Cc1c(C(=O)O)n(Cc2csc3ccc(F)cc23)c2ccc(F)cc12>>CN(C)C(=O)Cc1c(C(=O)O)n(Cc2csc3ccc(F)cc23)c2ccc(F)cc12 -US08685989B2,1,CCOC(=O)CBr.Nc1nc(=O)[nH]cc1F>>CCOC(=O)Cn1cc(F)c(N)nc1=O -US08367831B2,1,BrCC1OCCO1.O=c1ccc2ccncc2[nH]1>>O=c1ccc2ccncc2n1CC1OCCO1 -US08088790B2,1,NCc1cccnc1.O=[N+]([O-])c1c(Cl)nc2ccccc2c1Cl>>O=[N+]([O-])c1c(Cl)nc2ccccc2c1NCc1cccnc1 -US20040014766A1,1,C=O.Nc1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1>>CNc1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1 -US20110306623A1,6,CCCCc1nc(C)n(-c2ncc(OCc3ccccc3)cn2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCCc1nc(C)n(-c2ncc(O)cn2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US06465467B1,1,CC1CNCCN1.Clc1nccnc1OCC1COc2ccccc2O1>>CC1CN(c2nccnc2OCC2COc3ccccc3O2)CCN1 -US06710198B2,9,O.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F -US06710198B2,9,O.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>O=S(=O)(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F -US06888032B2,1,CC(C)c1ccccc1S.Cc1ccccc1I>>Cc1ccccc1Sc1ccccc1C(C)C -US20090286778A1,2,Clc1cnc2nc1Nc1ccc(OCCC3CCNCC3)c(c1)CCc1cncc(c1)N2.O=C(Cl)c1cnccn1>>O=C(c1cnccn1)N1CCC(CCOc2ccc3cc2CCc2cncc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US07932262B2,8,COc1cc(Br)cc(CO)c1N>>COc1cc(Br)cc(C=O)c1N -US08471005B2,1,C1CNCC(N2CCOCC2)C1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(N2CCCC(N3CCOCC3)C2)cc1 -US20040138286A1,6,Cc1c(NC2CC3CCC(C2)N3Cc2ccccc2)ccc2c1cnn2C1CCCCO1>>Cc1c(NC2CC3CCC(C2)N3Cc2ccccc2)ccc2[nH]ncc12 -US06197804B1,3,COc1cc[nH]c1C=O.O=C1Cc2c(ccc3oc(-c4ccccc4)nc23)N1>>COc1cc[nH]c1/C=C1\C(=O)Nc2ccc3oc(-c4ccccc4)nc3c21 -US07112697B1,1,Ic1ccccc1.SC1CCCCC1>>c1ccc(SC2CCCCC2)cc1 -US06620936B2,2,COc1cccc(N)c1.S=C(Cl)Oc1ccccc1>>COc1cccc(NC(=S)Oc2ccccc2)c1 -US08343996B2,6,COc1cccc(-c2cc(=O)n(C)c3ncc(C4(c5ccc(Cl)cc5)OCCO4)cc23)c1>>COc1cccc(-c2cc(=O)n(C)c3ncc(C(=O)c4ccc(Cl)cc4)cc23)c1 -US06794406B2,1,CC(C)c1c[nH]c2ccc(O)cc12.Cc1cc([N+](=O)[O-])cc(C)c1F>>Cc1cc([N+](=O)[O-])cc(C)c1Oc1ccc2[nH]cc(C(C)C)c2c1 -US04223132,6,O=C(Cc1ccccc1)OCc1ccccc1>>O=C(O)Cc1ccccc1 -US20060063828A1,3,COc1ccc(C=O)cc1Br.OB(O)c1cccs1>>COc1ccc(C=O)cc1-c1cccs1 -US08778937B2,1,Cc1c(CBr)cccc1C(F)(F)F.O=[N+]([O-])c1cc(Br)c2nc[nH]c2c1>>Cc1c(Cn2cnc3c(Br)cc([N+](=O)[O-])cc32)cccc1C(F)(F)F -US20130158009A1,6,COC(=O)c1ccc(O[C@H]2CCN(C3CCN(C(=O)OC(C)(C)C)CC3)C2=O)cn1>>COC(=O)c1ccc(O[C@H]2CCN(C3CCNCC3)C2=O)cn1 -US06790860B2,1,COc1ccc(CS[C@@H]2C[C@@H](COS(C)(=O)=O)N(S(C)(=O)=O)C2)cc1.NCc1ccccc1>>COc1ccc(CS[C@@H]2C[C@@H](CNCc3ccccc3)N(S(C)(=O)=O)C2)cc1 -US20120277265A1,1,Brc1cccc2cccnc12.Oc1cccc2cccnc12>>c1cnc2c(Oc3cccc4cccnc34)cccc2c1 -US20090253671A1,6,COC(=O)c1cccc(N2CC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)C2=O)c1>>Cc1[nH]c(C(=O)NC2CN(c3cccc(C(=O)O)c3)C2=O)c(Cl)c1Cl -US20150141354A1,7,O=c1ccoc2ccc(Cc3cc([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3Cl)cc12>>O=C1CCOc2ccc(Cc3cc([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3Cl)cc21 -US20140316089A1,1,CC(=O)c1cccc(Br)n1.CC(C)c1cccc(C(C)C)c1N>>CC(=Nc1c(C(C)C)cccc1C(C)C)c1cccc(Br)n1 -US20090143385A1,2,CC(C)N.CCOC(=O)c1ccc(NCc2c(-c3ccc(F)cc3)noc2C)nn1>>Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)NC(C)C)nn1 -US20150203479A1,2,C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.Cc1noc(C(=O)O)n1>>Cc1noc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)n1 -US20120046293A1,6,COCCCc1cc(C=O)cc(O[Si](C)(C)C(C)(C)C)c1>>COCCCc1cc(O)cc(C=O)c1 -US06664256B1,1,COc1ccc(-c2nnc(Cl)cc2-c2ccncc2)cc1.Oc1ccc(F)cc1F>>COc1ccc(-c2nnc(Oc3ccc(F)cc3F)cc2-c2ccncc2)cc1 -US07875728B2,2,Cc1ccc(C(=O)O)c(Cl)n1.NCC1=NN=C(N)C1=NNc1ccc(F)c(F)c1>>Cc1ccc(C(=O)NCC2=NN=C(N)C2=NNc2ccc(F)c(F)c2)c(Cl)n1 -US05157121,2,CCOC(=O)NS(=O)(=O)N(C)S(C)(=O)=O.COc1cc(OC)nc(N)n1>>COc1cc(OC)nc(NC(=O)NS(=O)(=O)N(C)S(C)(=O)=O)n1 -US20020103203A1,6,Cc1cc(NC(=O)c2cccc(CCc3cc(Nc4ccc(S(=O)(=O)N(C)C(c5ccccc5)c5ccccc5)cc4)n[nH]3)c2)ccc1C(C)C>>CNS(=O)(=O)c1ccc(Nc2cc(CCc3cccc(C(=O)Nc4ccc(C(C)C)c(C)c4)c3)[nH]n2)cc1 -US08367831B2,8,COc1ncc(CO)cc1F>>COc1ncc(C=O)cc1F -US20120015942A1,1,COC(=O)C1CCc2cc(OS(=O)(=O)C(F)(F)F)ccc2C1.COc1ccc(N)cc1>>COC(=O)C1CCc2cc(Nc3ccc(OC)cc3)ccc2C1 -US05859007,1,BrCc1ccccc1.COC(=O)c1cc(C)n[nH]1>>COC(=O)c1cc(C)nn1Cc1ccccc1 -US07368578B2,7,COc1cc(C=O)ccc1OCc1csc(N2CCOCC2)n1>>COc1cc(CO)ccc1OCc1csc(N2CCOCC2)n1 -US20060189673A1,7,CC1=C2OC(C)(C(=O)Nc3ccc(-n4ccnc4)cc3)CC2C(C)C([N+](=O)[O-])=C1C>>CC1=C(N)C(C)C2CC(C)(C(=O)Nc3ccc(-n4ccnc4)cc3)OC2=C1C -US20150065343A1,2,Cc1cc(/C=C/C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)sc1C(=O)O.NC1CC1>>Cc1cc(/C=C/C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)sc1C(=O)NC1CC1 -US07902372B2,1,CC(C)CCN.O=Cc1ccc(Oc2ccc(Br)cn2)cc1>>CC(C)CCNCc1ccc(Oc2ccc(Br)cn2)cc1 -US20120028983A1,6,CCCCc1nc(C)n(-c2ncc(OC3CCC(O[Si](C)(C)C(C)(C)C)CC3)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCCc1nc(C)n(-c2ncc(OC3CCC(O)CC3)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US04465508,2,CS(N)(=O)=O.O=C(O)c1cccc(Oc2cc(C(F)(F)F)ccc2Cl)c1>>CS(=O)(=O)NC(=O)c1cccc(Oc2cc(C(F)(F)F)ccc2Cl)c1 -US20110275719A1,7,O=C1CCC(c2cc(F)ccc2C(F)(F)F)(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1>>O=S(=O)(c1ccc(C(F)(F)F)cc1)C1(c2cc(F)ccc2C(F)(F)F)CCC(O)CC1 -US20070249670A1,2,COC(=O)[C@H](C)NCc1ccccc1.Nc1cc2ccccc2cc1C(=O)O>>COC(=O)[C@H](C)N(Cc1ccccc1)C(=O)c1cc2ccccc2cc1N -US20080182870A1,2,CC(=O)O.Nc1nc2ccc(-c3ccc(F)cc3)nc2c(=O)[nH]1>>CC(=O)Nc1nc2ccc(-c3ccc(F)cc3)nc2c(=O)[nH]1 -US03940394,1,CCOC(=O)CSc1nc(Cl)c(C)c(Cl)n1.NCc1ccc(Cl)cc1>>CCOC(=O)CSc1nc(Cl)c(C)c(NCc2ccc(Cl)cc2)n1 -US07625908B2,2,CNCCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12.O=C(O)C1CCCO1>>CN(CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)C1CCCO1 -US20140249132A1,1,COc1c(C(C)Cl)cc(C)c(C#N)c1C1CN(C(=O)OC(C)(C)C)C1.Cc1n[nH]c2ncnc(N)c12>>COc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(C)c(C#N)c1C1CN(C(=O)OC(C)(C)C)C1 -US20070167437A1,2,CCOc1ccsc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.NC(=O)CN1CCNCC1>>CCOc1ccsc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(N)=O)CC1 -US07105529B2,1,COc1ccc2c(c1)C(=O)C(=O)N2.NNc1ccc(S(N)(=O)=O)cc1>>COc1ccc2c(c1)C(=NNc1ccc(S(N)(=O)=O)cc1)C(=O)N2 -US20060160803A1,1,CNC(=O)c1cc(Cl)ccn1.O=C(CCc1ccc(O)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1>>CNC(=O)c1cc(Oc2ccc(CCC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 -US07741315B2,1,COc1c2c(c(C(=O)N(CCCCOS(C)(=O)=O)CCOCc3ccccc3)[nH]c1=O)CCN(Cc1ccc(F)c(Cl)c1)C2=O>>COc1c2c(c3n(c1=O)CCCCN(CCOCc1ccccc1)C3=O)CCN(Cc1ccc(F)c(Cl)c1)C2=O -US20100160320A1,1,CCOC(=O)[C@H]1CCCN(C(=O)c2ccccc2C)[C@H]1c1ccc(N)cc1.O=C1CCCC1>>CCOC(=O)[C@H]1CCCN(C(=O)c2ccccc2C)[C@H]1c1ccc(NC2CCCC2)cc1 -US05093328,2,CN.O=C(O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1>>CNC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1 -US20120004164A1,1,CCOC(=O)c1sc(N2CCNC2=O)nc1C.Fc1ccc(CBr)cc1>>CCOC(=O)c1sc(N2CCN(Cc3ccc(F)cc3)C2=O)nc1C -US20140066406A1,1,CP(C)(=O)c1ccc(N)cc1.Clc1nc(Cl)nc(Cl)n1>>CP(C)(=O)c1ccc(Nc2nc(Cl)nc(Cl)n2)cc1 -US20150119385A1,1,CN(C)CC1(O)CCNCC1.N#Cc1cnc(N)cc1F>>CN(C)CC1(O)CCN(c2cc(N)ncc2C#N)CC1 -US05082939,9,Clc1ccc(Cl)nn1.NN>>NNc1ccc(Cl)nn1 -US20130172360A1,7,CN1CCN(c2ccc(C(=O)OC(C)(C)C)c([N+](=O)[O-])c2)CC1>>CN1CCN(c2ccc(C(=O)OC(C)(C)C)c(N)c2)CC1 -US06806369B2,1,BrCc1ccccc1.OCCOc1cccc(O)c1>>OCCOc1cccc(OCc2ccccc2)c1 -US08138197B2,2,COc1cc(C(=O)O)cc(-c2ccccc2)n1.O=C1CC2(CCNCC2)Oc2ccc(-c3nnn[nH]3)cc21>>COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4nnn[nH]4)ccc2O3)cc(-c2ccccc2)n1 -US04841056,7,COC(=O)C1CN(C)C2Cc3cn(S(=O)(=O)c4ccccc4)c4cccc(c34)C12>>CN1CC(CO)C2c3cccc4c3c(cn4S(=O)(=O)c3ccccc3)CC21 -US20080015223A1,2,Cn1ncc(Br)c1N.O=C(Cl)c1cccc(I)c1>>Cn1ncc(Br)c1NC(=O)c1cccc(I)c1 -US20100197591A1,7,COC(=O)CC1CC=C(c2ccc(N3CCc4nc(C)nc(N)c4C3=O)cc2)CC1>>COC(=O)CC1CCC(c2ccc(N3CCc4nc(C)nc(N)c4C3=O)cc2)CC1 -US08507676B2,1,CC(O)c1c(F)cc2ncccc2c1F.O=C1NC(=O)c2ccccc21>>CC(c1c(F)cc2ncccc2c1F)N1C(=O)c2ccccc2C1=O -US04638000,6,CCOC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)N[C@H]1CSc2ccccc2N(CC(=O)OC(C)(C)C)C1=O>>CC(C)(C)OC(=O)CN1C(=O)[C@@H](N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O)CSc2ccccc21 -US20110257151A1,6,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(N3CCN(c4ccc(Cl)cc4)CC3)c1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(N2CCN(c3ccc(Cl)cc3)CC2)c1 -US20150232445A1,1,COC(=O)N1c2ccc(-c3cn[nH]c3)c(OC3CCC3)c2CC[C@@H]1C.CS(=O)(=O)OC1CCS(=O)(=O)CC1>>COC(=O)N1c2ccc(-c3cnn(C4CCS(=O)(=O)CC4)c3)c(OC3CCC3)c2CC[C@@H]1C -US07705023B2,1,CC(C)Oc1ccc(Br)cc1.CCOC(=O)c1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2[nH]1>>CCOC(=O)c1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1 -US07579347B2,1,FC(F)(F)c1ccc(-c2ccnc(Cl)c2)cc1.Oc1ccc2cccnc2c1>>FC(F)(F)c1ccc(-c2ccnc(Oc3ccc4cccnc4c3)c2)cc1 -US20090156572A1,2,CN(C(=O)c1ccc(N2CCOCC2)cc1)[C@@H]1CCN(C(=O)C2CCNCC2)C[C@H]1c1ccc(Cl)c(Cl)c1.CS(=O)(=O)Cl>>CN(C(=O)c1ccc(N2CCOCC2)cc1)[C@@H]1CCN(C(=O)C2CCN(S(C)(=O)=O)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US04075001,4,CCCCN(C)C(N)=C(C#N)C(N)=S>>CCCCN(C)c1nsc(N)c1C#N -US04008281,7,CC(=O)NC(=Cc1ccccc1)C(=O)O>>CC(=O)N[C@@H](Cc1ccccc1)C(=O)O -US20140194383A1,7,O=C(O)c1cc2cccc(O)c2cc1O>>OCc1cc2cccc(O)c2cc1O -US20080139558A1,1,CC(C)c1n[nH]c2ccccc12.O=c1cc(CBr)c2ccc(F)c(F)c2[nH]1>>CC(C)c1nn(Cc2cc(=O)[nH]c3c(F)c(F)ccc23)c2ccccc12 -US08980877B2,6,COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CN(C(C)=O)C1)O2>>CC(=O)N1CC2(CC(=O)c3cc(/C=C/C(=O)O)ccc3O2)C1 -US08686022B2,2,CC(C)(C)OC(=O)N1CCN(CC(=O)O)CC1.COc1c(NC(=O)c2cc3cccc(CN4CCNCC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)CN5CCN(C(=O)OC(C)(C)C)CC5)CC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O -US20050267306A1,6,CC(C)(C#N)C(=O)CCOCc1ccccc1>>CC(C)(C#N)C(=O)CCO -US20060069110A1,1,CN(C)C(CN)c1cccnc1.CN(c1ccnc(F)n1)c1ccnc(-c2ccccc2)n1>>CN(c1ccnc(NCC(c2cccnc2)N(C)C)n1)c1ccnc(-c2ccccc2)n1 -US20100016401A1,2,Cc1ccc(-c2ccccc2C(=O)O)cc1.O=C(NC[C@H]1NC[C@H]2C[C@H]21)c1cccc2occc12>>Cc1ccc(-c2ccccc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)c2cccc3occc23)cc1 -US07524860B2,3,Nc1nc2cc(-c3cccnc3)cc(Cl)n2n1.OB(O)c1cccnc1>>Nc1nc2cc(-c3cccnc3)cc(-c3cccnc3)n2n1 -US20110034526A1,1,Cc1nc2c(Cl)cccc2n1-c1cc(O)ccc1Cl.O=S(=O)(c1cccc(F)c1)C(F)(F)F>>Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cccc(S(=O)(=O)C(F)(F)F)c2)ccc1Cl -US20040082570A1,1,CC(C)(C)C(=O)OCn1c(=O)c2c(nc(Cl)n2-c2ccccc2C=O)n(COC(=O)C(C)(C)C)c1=O.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2nc3c(c(=O)n(COC(=O)C(C)(C)C)c(=O)n3COC(=O)C(C)(C)C)n2-c2ccccc2C=O)CC1 -US20140179715A1,1,N#Cc1cc(C=O)ccc1F.Oc1cc(F)cc(F)c1>>N#Cc1cc(C=O)ccc1Oc1cc(F)cc(F)c1 -US04853387,1,Clc1ncccn1.NCCN1CCC(C(O)(c2ccccc2)c2ccccc2)CC1>>OC(c1ccccc1)(c1ccccc1)C1CCN(CCNc2ncccn2)CC1 -US20080254992A1,1,C=CCN.Cc1c(C(=O)O)ccc(S(C)(=O)=O)c1F>>C=CCNc1c(S(C)(=O)=O)ccc(C(=O)O)c1C -US20130296327A1,6,COCC1(NC(=O)OC(C)(C)C)CCCC1>>COCC1(N)CCCC1 -US06472386B1,2,CCOC(=O)c1csc(N)n1.COc1cc(C(=O)O)cc(OC)c1OC>>CCOC(=O)c1csc(NC(=O)c2cc(OC)c(OC)c(OC)c2)n1 -US20080132481A1,2,CC(C)(C)N.Nc1ccc(Cl)cc1C(=O)O>>CC(C)(C)NC(=O)c1cc(Cl)ccc1N -US20100190688A1,7,COC(=O)C(CCC(=O)O)NC(=O)OC(C)(C)C>>COC(=O)C(CCCO)NC(=O)OC(C)(C)C -US06608059B1,4,C[Si](C)(C)N=[N+]=[N-].N#CCCCn1c(-c2cnco2)cc2cc(OCc3c(Cl)cccc3Cl)ccc21>>Clc1cccc(Cl)c1COc1ccc2c(c1)cc(-c1cnco1)n2CCCc1nnn[nH]1 -US08815891B2,7,CCOC(=O)c1cc(OC)c2c3c(c(=O)n(COC)c2c1)CCCN3>>COCn1c(=O)c2c(c3c(OC)cc(CO)cc31)NCCC2 -US07300950B2,9,N.O=C(Cl)c1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1>>NC(=O)c1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1 -US20120093875A1,2,CCCCCCCC(=O)O.CCCCCCCCCCCCCC[C@@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@@H](N)CO>>CCCCCCCCCCCCCC[C@@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@H](CO)NC(=O)CCCCCCC -US09079878B2,1,CNOC.O=C(Cl)c1ccc(S(F)(F)(F)(F)F)cc1>>CON(C)C(=O)c1ccc(S(F)(F)(F)(F)F)cc1 -US20090093454A1,1,CC(C)(C)OC(=O)NCCN1CCNCC1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>CC(C)(C)OC(=O)NCCN1CCN(c2cccc3nc(CN4CCC[C@H]5CCc6cccnc6[C@H]54)cn23)CC1 -US20100197715A1,7,COc1cc(C(F)(F)F)cc(SC)c1C(=O)NC1(c2ccccc2)CC(=O)CN(C)C1>>COc1cc(C(F)(F)F)cc(SC)c1C(=O)NC1(c2ccccc2)CC(O)CN(C)C1 -US04727067,1,COC(=O)c1ccc(O)cc1O.ClCC1CO1>>COC(=O)c1ccc(OCC2CO2)cc1O -US20100305135A1,9,CC1(C)O[C@@H]2CC[C@@H](c3cnc4c(Cl)nccn34)[C@@H]2O1.N>>CC1(C)O[C@@H]2CC[C@@H](c3cnc4c(N)nccn34)[C@@H]2O1 -US20070021443A1,7,C[C@H](c1cccnc1)n1c(=O)n(C(=O)OC(C)(C)C)c2ccc(Nc3cc(C#N)ccc3[N+](=O)[O-])nc21>>C[C@H](c1cccnc1)n1c(=O)n(C(=O)OC(C)(C)C)c2ccc(Nc3cc(C#N)ccc3N)nc21 -US04798838,6,CCOC(=O)C(C)(C)CCCCOc1ccc(NC(=O)CCCn2ccnc2)cc1>>CC(C)(CCCCOc1ccc(NC(=O)CCCn2ccnc2)cc1)C(=O)O -US20130184248A1,1,O=C(Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1)N1CCN(c2cc(Cl)ncn2)CC1.OCCO>>O=C(Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1)N1CCN(c2cc(OCCO)ncn2)CC1 -US20040097507A1,3,CN(C)C=O.Clc1cncc(Cl)c1>>O=Cc1ncc(Cl)cc1Cl -US06630600B1,6,CCOC(=O)C(Cc1cccc(OCCc2ccc(NC(=O)OC(C)(C)C)cc2)c1)OCC>>CCOC(Cc1cccc(OCCc2ccc(NC(=O)OC(C)(C)C)cc2)c1)C(=O)O -US20100210636A1,6,COc1ccc(CN2C(=O)OC(CNC(=O)c3ccc(F)cc3)(C(F)(F)F)c3cc(N4CCCC4=O)ccc32)cc1>>O=C1Nc2ccc(N3CCCC3=O)cc2C(CNC(=O)c2ccc(F)cc2)(C(F)(F)F)O1 -US06642226B2,2,O=C(Cl)c1ccccc1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCNCC2)[C@H](c2ccccc2)C1>>O=C(c1ccccc1)N1CCN([C@H]2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C[C@H]2c2ccccc2)CC1 -US07022850B2,1,CC(C)(C)OC(=O)NCCCN.CCC(Br)c1nc2snc(C)c2c(=O)n1Cc1ccccc1>>CCC(NCCCNC(=O)OC(C)(C)C)c1nc2snc(C)c2c(=O)n1Cc1ccccc1 -US20060148858A1,7,CCOC(=O)/C=C/c1cn(-c2ccc(Cl)cn2)nc1C(C)C>>CCOC(=O)CCc1cn(-c2ccc(Cl)cn2)nc1C(C)C -US20140024650A1,6,COc1ccc(-c2ccc(C#N)cn2)cc1F>>N#Cc1ccc(-c2ccc(O)c(F)c2)nc1 -US08084463B2,1,COc1cccc(C(O)(C(=O)O)c2cccc(OC)c2)c1.O[C@H]1CN2CCC1CC2>>COc1cccc(C(O)(C(=O)O[C@H]2CN3CCC2CC3)c2cccc(OC)c2)c1 -US20080058384A1,6,COc1cc(C2CC(=O)NC(C)=C2C(=O)Nc2ccc3[nH]nc(Cl)c3c2)ccc1Cl>>CC1=C(C(=O)Nc2ccc3[nH]nc(Cl)c3c2)C(c2ccc(Cl)c(O)c2)CC(=O)N1 -US06642231B2,9,NO.O=C1CCN(CCOc2ccccc2)CC1>>ON=C1CCN(CCOc2ccccc2)CC1 -US05607951,7,CCOC(=O)C=C[C@H]1CCCN1C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCC[C@@H]1C=CCO -US20090325930A1,3,COc1ccc2c(c1)CCC(Br)=C2.Cc1cccc([N+](=O)[O-])c1Br>>COc1ccc2c(c1)CCC(c1c(C)cccc1[N+](=O)[O-])=C2 -US20150025205A1,7,CC1Cc2c(cccc2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)C1=O>>CC1Cc2c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cccc2C1O -US06858639B2,5,O=Cc1ccc(Br)cc1F.OCCO>>Fc1cc(Br)ccc1C1OCCO1 -US07632838B2,2,Fc1ccc(N2CCNCC2)c(C(F)(F)F)c1.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1>>O=S(=O)(c1ccc(Cl)c(Cl)c1)N1CCN(c2ccc(F)cc2C(F)(F)F)CC1 -US20150133505A1,3,C#Cc1cccc(F)c1.O=C1C[C@H]2CCC[C@H]2N1c1ccc(I)cn1>>O=C1C[C@H]2CCC[C@H]2N1c1ccc(C#Cc2cccc(F)c2)cn1 -US07759387B2,3,CC(=O)OC(C)=O.Cc1c(O)cccc1O>>CC(=O)c1ccc(O)c(C)c1O -US20110082133A1,3,COC(=O)c1ccc(CCn2c(C=O)c(Cl)cc(Cl)c2=O)cc1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>COC=Cc1c(Cl)cc(Cl)c(=O)n1CCc1ccc(C(=O)OC)cc1 -US08384068B2,1,COC(=O)c1ccc(F)cc1.c1c[nH]cn1>>COC(=O)c1ccc(-n2ccnc2)cc1 -US07781474B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CNCCC1=O>>CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1=O -US06469004B1,6,Cc1cc(I)ccc1Nc1c(C(=O)NOC2CCCCO2)cc2nc[nH]c2c1F>>Cc1cc(I)ccc1Nc1c(C(=O)NO)cc2nc[nH]c2c1F -US20050038035A1,2,Cc1cccc(C(=O)O)c1-c1ccc(C(F)(F)F)cc1.Nc1ccc(NC(=O)Cc2ccccn2)cc1>>Cc1cccc(C(=O)Nc2ccc(NC(=O)Cc3ccccn3)cc2)c1-c1ccc(C(F)(F)F)cc1 -US20140031338A1,3,CCOC(=O)C=O.O=C1CCCCC1>>CCOC(=O)C(O)C1CCCCC1=O -US20120207763A1,3,C#CC(OCC)OCC.CCC(CC)Nc1nc(Cl)ncc1Br>>CCOC(C#Cc1cnc(Cl)nc1NC(CC)CC)OCC -US20080051418A1,1,CCOC(=O)c1cc(OC(C)C)n[nH]1.ClCc1ccc2ccccc2n1>>CCOC(=O)c1cc(OC(C)C)nn1Cc1ccc2ccccc2n1 -US20080318943A1,3,COc1cnccc1B(O)O.Nc1c2c(nc3c(Br)cccc13)CN(C1CCC1)C2=O>>COc1cnccc1-c1cccc2c(N)c3c(nc12)CN(C1CCC1)C3=O -US20100256124A1,1,Cn1c(=O)ccc2ncc(Cl)c(CCN3CCC(N)CC3)c21.O=Cc1cc2c(cn1)OCCO2>>Cn1c(=O)ccc2ncc(Cl)c(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c21 -US20130137675A1,6,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ccnn1-c1ccccc1>>CC(C)(C)OC(=O)Nc1ccnn1-c1ccccc1 -US20080027035A1,6,CC(C)(C)OC(=O)NC(CC(=O)N1CCCC1CNC(=O)C(F)(F)F)Cc1ccccc1F>>CC(C)(C)OC(=O)NC(CC(=O)N1CCCC1CN)Cc1ccccc1F -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(N2CCc3ccccc3C2)nc1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc(N2CCc3ccccc3C2)nc1-c1ccc(C)cc1 -US20030162795A1,1,NC1CC1.O=Cc1ccc(-c2cc3ncnc(Nc4ccc5[nH]ccc5c4)c3s2)cc1>>c1nc(Nc2ccc3[nH]ccc3c2)c2sc(-c3ccc(CNC4CC4)cc3)cc2n1 -US07220744B2,2,CS(=O)(=O)c1ccc(OC2CCCCC2)c(C(=O)O)c1.CS(=O)(=O)c1cnc(N2CCNCC2)s1>>CS(=O)(=O)c1ccc(OC2CCCCC2)c(C(=O)N2CCN(c3ncc(S(C)(=O)=O)s3)CC2)c1 -US04448964,1,ClCc1ccccc1.OC1CCCNC1>>OC1CCCN(Cc2ccccc2)C1 -US04680404,1,C=O.CCCCSCCCc1cc(O)c2c(c1)NC(C)CC2CCO>>CCCCSCCCc1cc(O)c2c(c1)N(C)C(C)CC2CCO -US20130165485A1,6,COC(=O)c1ccn(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)n1>>O=C(O)c1ccn(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)n1 -US20140155428A1,2,CC(C)(C)OC(=O)C(NS(=O)(=O)c1cccc(C(=O)O)c1)c1ccccc1.COc1ccc([C@@H](O)Cc2c(Cl)c[n+]([O-])cc2Cl)cc1OC>>COc1ccc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2cccc(S(=O)(=O)NC(C(=O)OC(C)(C)C)c3ccccc3)c2)cc1OC -US05182399,1,CC(C)(C)c1ccc(C(=O)CCCCl)cc1.O=C(c1nc2ccccc2n1Cc1ccc(F)cc1)C1CCNCC1>>CC(C)(C)c1ccc(C(=O)CCCN2CCC(C(=O)c3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1 -US04423255,2,CC1(C)[C@H](C=C(Cl)Cl)[C@@H]1C(=O)Cl.OC1Cc2cccc(-c3ccccc3)c2C1>>CC1(C)[C@H](C=C(Cl)Cl)[C@@H]1C(=O)OC1Cc2cccc(-c3ccccc3)c2C1 -US20110039857A1,1,Cc1cccc(-c2sc(C3CC3)nc2C(=O)N2CCC[C@@H](N)C2)c1.FC(F)(F)c1ccnc(Cl)n1>>Cc1cccc(-c2sc(C3CC3)nc2C(=O)N2CCC[C@@H](Nc3nccc(C(F)(F)F)n3)C2)c1 -US07855218B2,6,COC(=O)[C@H](CC#Cc1ccc(OCc2ccccc2F)cn1)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](N)CC#Cc1ccc(OCc2ccccc2F)cn1 -US20020123437A1,7,O=C1CCCCCCC=CCCCCCCC1>>O=C1CCCCCCCCCCCCCCC1 -US08530648B2,6,CC(C)(C)OC(=O)N1CCC2(CCCNC2=O)CC1>>O=C1NCCCC12CCNCC2 -US20130053386A1,7,CCn1nc(-c2cccc(C#N)c2)cc1Oc1ccc(F)cc1[N+](=O)[O-]>>CCn1nc(-c2cccc(C#N)c2)cc1Oc1ccc(F)cc1N -US20130079373A1,6,CCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1ccc(CNS(=O)(=O)NC(=O)OC(C)(C)C)cc1>>CCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1ccc(CNS(N)(=O)=O)cc1 -US06642231B2,1,COCCCCCCCl.O=C1CCNCC1>>COCCCCCCN1CCC(=O)CC1 -US20120232061A1,6,COc1ccnc(COc2ccccc2-c2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)c1>>COc1ccnc(COc2ccccc2-c2ccc3c(c2)CCNCC3)c1 -US20130315874A1,4,C#CCCCCCc1cn(C(=O)OC(C)(C)C)c(N)n1.CCCCCCCCc1ccc(C(=O)NCCN=[N+]=[N-])cc1>>CCCCCCCCc1ccc(C(=O)NCCn2cc(CCCCCc3cn(C(=O)OC(C)(C)C)c(N)n3)nn2)cc1 -US20100197634A1,3,CC(C)(O)/C=C/B(O)O.O=c1[nH]ccc2c(Nc3c(Cl)cc(-c4ccn[nH]4)cc3Cl)nc3ccc(Br)cc3c12>>CC(C)(O)/C=C/c1ccc2nc(Nc3c(Cl)cc(-c4ccn[nH]4)cc3Cl)c3cc[nH]c(=O)c3c2c1 -US20100099695A1,2,CC(C)[Si](Oc1cccc2c1CNCC2)(C(C)C)C(C)C.O=C([O-])CCCCO>>CC(C)[Si](Oc1cccc2c1CN(C(=O)CCCCO)CC2)(C(C)C)C(C)C -US04735952,8,Fc1ccc(SC2CCNCC2)cc1.O=C(OO)c1cccc(Cl)c1>>O=S(c1ccc(F)cc1)C1CCNCC1 -US20140057953A1,3,CN(C)c1cccc(B(O)O)c1.CN(Cc1cccc(O)c1)C(=O)c1ccc(Br)s1>>CN(Cc1cccc(O)c1)C(=O)c1ccc(-c2cccc(N(C)C)c2)s1 -US20080275021A1,2,CC(C)(C(=O)Cl)c1cc(Cl)cc(Cl)c1.CN[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(F)cc1>>CN(C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(F)cc1 -US20070049581A1,6,CCOC(=O)[C@H]1CCCN1C1CCN(C(=O)[C@@H](Cc2cc(Cl)c(N)c(C(F)(F)F)c2)OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)CC1>>Nc1c(Cl)cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCC[C@@H]3C(=O)O)CC2)cc1C(F)(F)F -US20140249133A1,2,CN.COc1cnc(-c2nn(Cc3c(Cl)ccc(C(=O)O)c3Cl)c3ccccc23)nc1Nc1ccncc1>>CNC(=O)c1ccc(Cl)c(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc32)c1Cl -US20140080788A1,7,O=C1CSc2c(Br)cccc2N1>>Brc1cccc2c1SCCN2 -US20150045351A1,6,CC(C)(C)OC(=O)N1CCc2cccc3[nH]cc(c23)C1>>c1cc2c3c(c[nH]c3c1)CNCC2 -US04639451,6,CC(=O)SC(C)C(=O)Nc1ccc(C2=NNC(=O)CC2C)cc1>>CC(S)C(=O)Nc1ccc(C2=NNC(=O)CC2C)cc1 -US06323213B1,2,CO.O=C(F)c1cc(F)c(F)c(Br)c1F>>COC(=O)c1cc(F)c(F)c(Br)c1F -US05130313,1,C1=C(c2ccccc2)CCNC1.ClCCCBr>>ClCCCN1CC=C(c2ccccc2)CC1 -US05032588,7,CCOC(=O)CCCc1sc(C(CC)c2ccc(CC(C)C)cc2)nc1O>>CCC(c1ccc(CC(C)C)cc1)c1nc(O)c(CCCCO)s1 -US20100069362A1,2,CC(=O)Cl.O=C1CNCCN1Cc1ccc(CCn2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)cc1>>CC(=O)N1CCN(Cc2ccc(CCn3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)cc2)C(=O)C1 -US20140171403A1,6,Cc1cc(C)cc(COC(=O)N2CCC(NC(=O)OC(C)(C)C)CC2)c1>>Cc1cc(C)cc(COC(=O)N2CCC(N)CC2)c1 -US08293902B2,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCN(C(C)=O)CC1.Oc1ccc2[nH]ncc2c1>>COc1cc2c(Oc3ccc4[nH]ncc4c3)ncnc2cc1OCCCN1CCN(C(C)=O)CC1 -US07732463B2,1,Brc1ccccc1I.COc1ccc(S)cc1>>COc1ccc(Sc2ccccc2Br)cc1 -US20080069968A1,1,CCCCCOc1ccc(O)cc1.CCOC(=O)Oc1ccc(/C=C/C(=O)O)cc1>>CCCCCOc1ccc(OC(=O)/C=C/c2ccc(OC(=O)OCC)cc2)cc1 -US05597826,3,CN1CCN(c2cccc3ccc([Sn](C)(C)C)cc23)CC1.CNS(=O)(=O)c1cccc(Br)c1>>CNS(=O)(=O)c1cccc(-c2ccc3cccc(N4CCN(C)CC4)c3c2)c1 -US07425631B2,7,N#Cc1ccc2c(c1)OCCC2=O>>N#Cc1ccc2c(c1)OCC[C@@H]2O -US06344562B1,2,CC(C)(C)OC(=O)C[C@H](N)C(=O)Nc1ccccc1.Cc1nc(NC(=N)N)sc1C(=O)Nc1cccc(C(=O)O)c1>>Cc1nc(NC(=N)N)sc1C(=O)Nc1cccc(C(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)Nc2ccccc2)c1 -US20090062265A1,1,CC(C)(C)OC(=O)N1CCOc2cnc(C=O)cc21.NC1CCN(CC2Cn3c(=O)cnc4ccc(F)c2c43)CC1>>CC(C)(C)OC(=O)N1CCOc2cnc(CNC3CCN(CC4Cn5c(=O)cnc6ccc(F)c4c65)CC3)cc21 -US07943607B2,6,COC[C@H](C)Oc1cc(Oc2ccc3c(c2)OCCN(C)C3=O)cc(C(=O)Nc2cnc(C)cn2)c1>>Cc1cnc(NC(=O)c2cc(Oc3ccc4c(c3)OCCN(C)C4=O)cc(O[C@@H](C)CO)c2)cn1 -US20110178053A1,3,Brc1cnc2[nH]c3cnc(-c4cccnc4)cc3c2c1.CN(C)CCCOc1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CN(C)CCCOc1ccc(-c2cnc3[nH]c4cnc(-c5cccnc5)cc4c3c2)cc1 -US20100210628A1,3,CNc1nc(Cl)nc(N2CCC(C(=O)NCc3ccccc3C(F)(F)F)CC2)n1.OB(O)c1ccccc1>>CNc1nc(-c2ccccc2)nc(N2CCC(C(=O)NCc3ccccc3C(F)(F)F)CC2)n1 -US05808111,9,CC(=O)O[C@@H]1[C@@H](OC(C)=O)C(C)(Br)O[C@H](C(=O)O)[C@H]1OC(C)=O.[N-]=[N+]=[N-]>>CC(=O)O[C@@H]1[C@@H](OC(C)=O)C(C)(N=[N+]=[N-])O[C@H](C(=O)O)[C@H]1OC(C)=O -US08327467B2,6,Cc1cccc(/C=C/c2ccc(C(=O)OC(C)(C)C)c(Nc3ccc(F)cc3)c2)c1>>Cc1cccc(/C=C/c2ccc(C(=O)O)c(Nc3ccc(F)cc3)c2)c1 -US20070066624A1,1,O=C1N(C2CCOCC2)CC(c2cccc(Cl)c2)N1C1CCNCC1.O=Cc1ccc2c(c1)CNC2=O>>O=C1NCc2cc(CN3CCC(N4C(=O)N(C5CCOCC5)CC4c4cccc(Cl)c4)CC3)ccc21 -US06300368B1,2,CS(=O)(=O)Cl.Nc1cc([N+](=O)[O-])ccc1F>>CS(=O)(=O)Nc1cc([N+](=O)[O-])ccc1F -US20050272778A1,9,BrC(Br)(Br)Br.O=C1CC(c2ccc(CO)cc2Br)S(=O)(=O)N1>>O=C1CC(c2ccc(CBr)cc2Br)S(=O)(=O)N1 -US20050113346A1,6,CC#CCOc1ccc(S(=O)(=O)N(C)C(C(=O)OC)c2ccc(O[Si](C)(C)C(C)(C)C)cc2)cc1>>CC#CCOc1ccc(S(=O)(=O)N(C)C(C(=O)OC)c2ccc(O)cc2)cc1 -US20070072813A1,7,COc1c(F)cc(C(=O)O)cc1F>>COc1c(F)cc(CO)cc1F -US07704995B2,2,Nc1cccc(Br)c1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1cccc(Br)c1 -US20020042411A1,1,COC(=O)c1c(N)sc2ccc(C)cc12.O=[N+]([O-])c1ccccc1F>>COC(=O)c1c(Nc2ccccc2[N+](=O)[O-])sc2ccc(C)cc12 -US04005082,1,CN(N)C1=NOCc2ccc(Cl)cc21.O=Cc1ccc([N+](=O)[O-])cc1>>CN(N=Cc1ccc([N+](=O)[O-])cc1)C1=NOCc2ccc(Cl)cc21 -US09115152B2,6,O=S(=O)(c1ccccc1)N1CC2COCC(C1)N2Cc1ccccc1>>O=S(=O)(c1ccccc1)N1CC2COCC(C1)N2 -US20100152216A1,1,CC(C)N1C(=O)NC(C)(c2ccccc2)C1=O.COC(=O)CBr>>COC(=O)CN1C(=O)N(C(C)C)C(=O)C1(C)c1ccccc1 -US08129361B2,7,O=C(O)C=Cc1cccc(Cl)c1>>OCC=Cc1cccc(Cl)c1 -US08183262B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.FC(F)(F)c1cc(-c2ccc(Cl)cc2)cc(-c2cccc(Br)c2)n1>>Nc1ccc(-c2cccc(-c3cc(-c4ccc(Cl)cc4)cc(C(F)(F)F)n3)c2)cn1 -US08022062B2,3,CC[Mg+].O=Cc1ccccn1>>CCC(O)c1ccccn1 -US05118701,1,COC(=O)c1ccc2c(c1)C(NC(=O)CCl)c1ccccc1CO2.c1c[nH]cn1>>COC(=O)c1ccc2c(c1)C(NC(=O)Cn1ccnc1)c1ccccc1CO2 -US04018897,1,CCNCC.ClCCC=C(c1ccccc1)C1Cc2ccccc2C1>>CCN(CC)CCC=C(c1ccccc1)C1Cc2ccccc2C1 -US08324248B2,7,CC(=O)[C@H]1CCN(Cc2ccccc2)C[C@@H]1c1ccc(F)c(F)c1>>C[C@H](O)[C@H]1CCN(Cc2ccccc2)C[C@@H]1c1ccc(F)c(F)c1 -US20100063047A1,9,Cc1csc2ncnc(Br)c12.N>>Cc1csc2ncnc(N)c12 -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1[C@H](O)CS(=O)(=O)Cc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4[C@H](O)CS(=O)(=O)Cc4ccccc4)cc3)cc2)CC1 -US20100324073A1,1,CCS(=O)(=O)c1cccc(Br)c1.Oc1cccc(-c2c(Cc3ccccc3)nn3c(C(F)(F)F)ccnc23)c1>>CCS(=O)(=O)c1cccc(Oc2cccc(-c3c(Cc4ccccc4)nn4c(C(F)(F)F)ccnc34)c2)c1 -US20050245563A1,1,CC(C)(C)OC(=O)NCCCBr.O=c1[nH]c2ccccc2c(=O)o1>>CC(C)(C)OC(=O)NCCCn1c(=O)oc(=O)c2ccccc21 -US04103022,2,Nc1ccc2c(c1)C(F)(F)OC(F)(F)O2.O=C=NC(=O)c1c(F)cccc1F>>O=C(NC(=O)c1c(F)cccc1F)Nc1ccc2c(c1)C(F)(F)OC(F)(F)O2 -US04618359,2,CCSc1ccc(Oc2ccc(Br)cc2Cl)cc1C(=O)Cl.OC1CCOC1>>CCSc1ccc(Oc2ccc(Br)cc2Cl)cc1C(=O)OC1CCOC1 -US20070142638A1,2,N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)O.O=C(O)c1cc2ccccc2o1>>O=C(NCCC[C@H](NC(=O)c1cc2ccccc2o1)C(=O)O)OCc1ccccc1 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2ccccc2Cl)cc1.O=C(O)c1cccc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccccc2Cl)C(=O)c2cccc3cc[nH]c23)cc1 -US06683097B2,3,C[Mg+].O=Cc1cn(-c2ccc(Cl)c(Cl)c2)cn1>>CC(O)c1cn(-c2ccc(Cl)c(Cl)c2)cn1 -US20070225340A1,3,CCOC(=O)c1cccc(B(O)O)c1.Cc1cccc(Br)c1I>>CCOC(=O)c1cccc(-c2c(C)cccc2Br)c1 -US05532236,1,O=c1[nH]c2cc([N+](=O)[O-])c(F)cc2n2c(=O)[nH]nc12.c1c[nH]cn1>>O=c1[nH]c2cc([N+](=O)[O-])c(-n3ccnc3)cc2n2c(=O)[nH]nc12 -US20100240658A1,2,CNCC(=O)OC.COCc1cc(-c2nc(-c3cccc(C(=O)Cl)c3)no2)ccc1-c1ccccc1C>>COCc1cc(-c2nc(-c3cccc(C(=O)N(C)CC(=O)OC)c3)no2)ccc1-c1ccccc1C -US20090325942A1,6,CCOC(=O)C(CC1CCOCC1)c1ccc2c(c1)N(C)c1ccccc1S2(=O)=O>>CN1c2ccccc2S(=O)(=O)c2ccc(C(CC3CCOCC3)C(=O)O)cc21 -US08153644B2,1,CC(C)(C)OC(=O)N1CC[C@H](Nc2ccc([N+](=O)[O-])cn2)C1.CI>>CN(c1ccc([N+](=O)[O-])cn1)[C@H]1CCN(C(=O)OC(C)(C)C)C1 -US07329658B2,1,CC(C)(C)N1CC(O)C1.Cc1nc(Cl)n2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2n1>>Cc1nc(OC2CN(C(C)(C)C)C2)n2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2n1 -US20050038072A1,1,ClCc1cccnc1.O=C1CCNCC1C(c1ccc(F)cc1)c1ccc(F)cc1>>O=C1CCN(Cc2cccnc2)CC1C(c1ccc(F)cc1)c1ccc(F)cc1 -US20060167023A1,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.Fc1cccc(COc2ccc3c(c2)CCNC3)c1>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2cc(OCc3cccc(F)c3)ccc2C1 -US20090156642A1,1,CN(Cc1nc(-c2ccccc2F)c(Br)s1)C(=O)OC(C)(C)C.Sc1cccc(Br)c1>>CN(Cc1nc(-c2ccccc2F)c(Sc2cccc(Br)c2)s1)C(=O)OC(C)(C)C -US20100130737A1,1,CCOC(=O)CBr.O=Cc1cc(Br)ccc1O>>CCOC(=O)COc1ccc(Br)cc1C=O -US20140088078A1,1,COC(=O)c1c(NC(=O)C(C)(C)C)ccc([C@H]2CCO[C@H]2COS(C)(=O)=O)c1NC(C)=O>>COC(=O)c1c(NC(=O)C(C)(C)C)ccc2c1N(C(C)=O)C[C@@H]1OCC[C@H]21 -US04273929,9,CCCCC[C@@H]1CC[C@@H](c2cnc(-c3ccc(C(N)=O)cc3)nc2)CC1>>CCCCC[C@@H]1CC[C@@H](c2cnc(-c3ccc(C#N)cc3)nc2)CC1 -US20130324576A1,2,Cc1nn(C)c(C)c1S(=O)(=O)Cl.Clc1ccc(CC2CCNCC2)cc1Cl>>Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Cc2ccc(Cl)c(Cl)c2)CC1 -US20070265298A1,6,COC(=O)c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)cc2)cc1Cl>>O=C(O)c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)cc2)cc1Cl -US20130172317A1,6,COC(=O)[C@@H](C)Cn1c(=O)n(C)c(=Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(OC)cc2)c1=O>>COc1ccc(Cn2c(=Nc3ccc(OC(C)C)c(Cl)c3)n(C)c(=O)n(C[C@H](C)C(=O)O)c2=O)cc1 -US06281356B1,1,C1COCCN1.Cn1ccc2ccc(I)cc21>>Cn1ccc2ccc(N3CCOCC3)cc21 -US04293697,2,CN(C)CCN=C=S.NCCNCc1nccs1>>CN(C)CCNC(=S)NCCNCc1nccs1 -US20130210795A1,6,COC(=O)c1cccc([C@H](C)Sc2nc(N)c(C#N)c(-c3ccc(OCCO)cc3)c2C#N)c1>>C[C@H](Sc1nc(N)c(C#N)c(-c2ccc(OCCO)cc2)c1C#N)c1cccc(C(=O)O)c1 -US06310095B1,6,COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC[C@@H]2CSCN2C(=O)OC(C)(C)C)cc1-c1ccccc1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC[C@@H]2CSCN2)cc1-c1ccccc1 -US20100099690A1,1,CCCCCI.COc1ccc(Cn2cnc3[nH]c(=O)n(-c4ccccc4)c(=O)c32)cc1>>CCCCCn1c(=O)n(-c2ccccc2)c(=O)c2c1ncn2Cc1ccc(OC)cc1 -US20140275172A1,6,Cc1c(CCC(=O)OC(C)(C)C)ccc(OCc2cc(F)cc3cc(C#N)oc23)c1C>>Cc1c(CCC(=O)O)ccc(OCc2cc(F)cc3cc(C#N)oc23)c1C -US08513239B2,2,C1CCNCC1.CCOc1nc(C(C)(C)C)ncc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl>>CCOc1nc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCCCC1 -US05760032,1,CCOC(=O)c1cc2ccccc2[nH]1.N#CCBr>>CCOC(=O)c1cc2ccccc2n1CC#N -US20110105509A1,2,CC(=O)O.CCOC(=O)Cn1c(C)cc2c(N)cccc21>>CCOC(=O)Cn1c(C)cc2c(NC(C)=O)cccc21 -US04814344,3,C=O.CC(=O)c1cn(C)c2ccc(C)cc12.CNC>>Cc1ccc2c(c1)c(C(=O)CCN(C)C)cn2C -US20030078251A1,7,CCOC(=O)CC(=O)c1ccc([N+](=O)[O-])c(C)c1>>CCOC(=O)CC(O)c1ccc([N+](=O)[O-])c(C)c1 -US05798316,7,COC(=O)C(C)Oc1ccc(C=O)cc1>>COC(=O)C(C)Oc1ccc(CO)cc1 -US06770646B2,1,BrCc1ccccc1.CC(C)Cc1nn(C)c(=O)c2c[nH]cc12>>CC(C)Cc1nn(C)c(=O)c2cn(Cc3ccccc3)cc12 -US09067937B2,3,CC(C)(C)OC(=O)N[C@@H]1CCCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(Cl)nc34)cn2)C1.CC1(C)OB(c2cc(F)c(O)c(Cl)c2)OC1(C)C>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)nc34)cn2)C1 -US20090082399A1,2,COc1ccc(N=C=O)cc1.O=C(c1ccc(F)cc1)N1CCC[C@H](O)C1>>COc1ccc(NC(=O)O[C@H]2CCCN(C(=O)c3ccc(F)cc3)C2)cc1 -US20120208800A1,2,CC(C)OC(=O)Cl.C[C@@H](CC(N)=O)Nc1ccc(Br)cc1>>CC(C)OC(=O)NC(=O)C[C@H](C)Nc1ccc(Br)cc1 -US05166170,2,CCCCCCCCOC(=O)Cl.Nc1ccccc1C1Cc2ccccc2N1>>CCCCCCCCOC(=O)Nc1ccccc1C1Cc2ccccc2N1 -US08658636B2,6,COC(=O)c1c(CN2CCC(N3CCOCC3)CC2)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc12>>CS(=O)(=O)c1ccc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(N4CCOCC4)CC3)c(C(=O)O)c2c1 -US06713474B2,3,CC1(C)OB(c2ccc(Oc3ccccc3)c(F)c2)OC1(C)C.CN1CCN([C@@H]2CC[C@@H](n3cc(I)c4c(Cl)ncnc43)CC2)CC1>>CN1CCN([C@@H]2CC[C@@H](n3cc(-c4ccc(Oc5ccccc5)c(F)c4)c4c(Cl)ncnc43)CC2)CC1 -US20110319445A1,6,CCOC(=O)Cc1ccc(OC)c(-c2ncc(C)cc2CN(CC)C(=O)NCc2ccccc2)c1>>CCN(Cc1cc(C)cnc1-c1cc(CC(=O)O)ccc1OC)C(=O)NCc1ccccc1 -US20070124152A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccccc3)cc2n(CCN2CCOCC2)c1=O.NC1CCC1>>O=C(NC1CCC1)c1c(O)c2ncc(Cc3ccccc3)cc2n(CCN2CCOCC2)c1=O -US20150266834A1,3,CC(C)(C)COc1ccc(B(O)O)cc1.COc1nc(Cl)nc(Cl)n1>>COc1nc(Cl)nc(-c2ccc(OCC(C)(C)C)cc2)n1 -US20110098290A1,6,COC(=O)c1cc(C(C)C)c(OCc2ccccc2)cc1OC>>COC(=O)c1cc(C(C)C)c(O)cc1OC -US20150218096A1,7,COC(=O)c1cnc2c(Br)nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1>>O=C(c1c(Cl)cccc1C(F)(F)F)n1nc(Br)c2ncc(CO)cc21 -US09000181B2,1,CCOC(=O)C(C)Br.Cc1cc(C)[nH]n1>>CCOC(=O)C(C)n1nc(C)cc1C -US08921397B2,2,CC[C@H](O)CC(=O)OC.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CC[C@H](O)CC(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1 -US20130217706A1,1,Brc1ccccc1.Nc1cccc(F)c1>>Fc1cccc(Nc2ccccc2)c1 -US20150087663A1,1,CC[C@H](N)c1nc2cccc(Cl)c2c(=O)n1-c1ccc(F)cc1.Cn1cnc(-c2c(N)ncnc2Cl)n1>>CC[C@H](Nc1ncnc(N)c1-c1ncn(C)n1)c1nc2cccc(Cl)c2c(=O)n1-c1ccc(F)cc1 -US06790844B2,9,N#Cc1ccsc1CBr.[C-]#N>>N#CCc1sccc1C#N -US20100130738A1,6,COc1ccc(-c2n[nH]c(=O)cc2C)cc1>>Cc1cc(=O)[nH]nc1-c1ccc(O)cc1 -US05034417,7,CC(=O)c1ccc(NS(C)(=O)=O)c(Sc2ccc(F)cc2F)c1>>CC(O)c1ccc(NS(C)(=O)=O)c(Sc2ccc(F)cc2F)c1 -US08143263B2,1,CC(C)(C)[Si](OCCOC[C@H](O)C(=O)Nc1ccc(Cl)cn1)(c1ccccc1)c1ccccc1.Cc1ccccc1-n1nnc2c(Cl)ncnc21>>Cc1ccccc1-n1nnc2c(O[C@@H](COCCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C(=O)Nc3ccc(Cl)cn3)ncnc21 -US07977358B2,2,C1CCN(C2CCNCC2)C1.Cc1ccc(-n2nc(C)c(C(=O)O)c2C)cc1C(F)(F)F>>Cc1ccc(-n2nc(C)c(C(=O)N3CCC(N4CCCC4)CC3)c2C)cc1C(F)(F)F -US20040122001A1,6,CC(C)(C)[Si](C)(C)OCC[C@@H]1OCCc2cc(-c3cccnc3)ccc21>>OCC[C@@H]1OCCc2cc(-c3cccnc3)ccc21 -US20130225561A1,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1cc2c(cc1F)C(=O)CCO2>>CO/C=C1\CCOc2cc(C#N)c(F)cc21 -US20080269249A2,1,C1COCCN1.Clc1cnccn1>>c1cnc(N2CCOCC2)cn1 -US20080214621A1,7,COc1ccc2c(Cl)c(C=O)ccc2c1>>COc1ccc2c(Cl)c(CO)ccc2c1 -US20100331326A1,1,Brc1cnc2ccccc2c1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2cnc3ccccc3c2)C1=O -US20050267131A1,6,CC1(C)CCCn2c1nc(C(=O)NCc1ccc(F)cc1-n1cncn1)c(OCc1ccccc1)c2=O>>CC1(C)CCCn2c1nc(C(=O)NCc1ccc(F)cc1-n1cncn1)c(O)c2=O -US08217043B2,1,CC(C)(C)OC(=O)Nn1cccc1.Fc1ccccc1CCl>>CC(C)(C)OC(=O)N(Cc1ccccc1F)n1cccc1 -US20110263571A1,1,CC1(C)CNC(=O)O1.Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3F)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CC(C)(C)OC4=O)cc3F)CC2)c(C)c1 -US20100048532A1,2,CNCCO.COCCn1c(C)nc2cc(C(=O)O)cc(OCc3ccccc3)c21>>COCCn1c(C)nc2cc(C(=O)N(C)CCO)cc(OCc3ccccc3)c21 -US07550473B2,2,CO.O=C(O)Cc1ccccc1Cl>>COC(=O)Cc1ccccc1Cl -US20120165331A1,6,Cc1ccc(S(=O)(=O)n2cc(CN3CCC4(CCN(C(=O)OC(C)(C)C)C4)C3=O)c3ccccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(CN3CCC4(CCNC4)C3=O)c3ccccc32)cc1 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2ccc(F)c(F)c2)cc1.O=C(O)c1cccc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccc(F)c(F)c2)C(=O)c2cccc3cc[nH]c23)cc1 -US20090163462A1,6,COc1ccc(Oc2ccc(C#N)cc2)cc1>>N#Cc1ccc(Oc2ccc(O)cc2)cc1 -US20050026836A1,2,CCOC(=O)[C@@H]1CCCC[C@@H]1N.O=S(=O)(Cl)c1ccc2c(Cl)cnc(Cl)c2c1>>CCOC(=O)[C@@H]1CCCC[C@@H]1NS(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1 -US20110098272A1,6,Cc1nc(-c2ccc(F)cc2)c(-c2ccncn2)n1C1CCN(C(=O)OC(C)(C)C)CC1>>Cc1nc(-c2ccc(F)cc2)c(-c2ccncn2)n1C1CCNCC1 -US08455521B2,1,CC(C)(C)OC(=O)N[C@H](COS(C)(=O)=O)CC1CCC(F)(F)CC1.CN>>CNC[C@H](CC1CCC(F)(F)CC1)NC(=O)OC(C)(C)C -US07709519B2,1,CC(=O)[O-].O=C(C(C(=O)c1cccc(CCl)c1)=C1Nc2ccccc2N1)c1cc(F)cc(F)c1>>CC(=O)OCc1cccc(C(=O)C(C(=O)c2cc(F)cc(F)c2)=C2Nc3ccccc3N2)c1 -US05939268,7,COC(=O)/C=C/c1ccoc1>>COC(=O)CCc1ccoc1 -US04272539,2,CN.COC(=O)C1(C)NCCc2c1[nH]c1ccccc21>>CNC(=O)C1(C)NCCc2c1[nH]c1ccccc21 -US20100003250A1,1,CN.O=CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccncc4)cc3)nc21>>CNCCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccncc4)cc3)nc21 -US20090069370A1,6,COC(=O)c1ccc(COc2ccc3c(c2)CCN(C2CCN(C4CCC4)CC2)C3=O)cc1>>O=C(O)c1ccc(COc2ccc3c(c2)CCN(C2CCN(C4CCC4)CC2)C3=O)cc1 -US04916149,6,COC(=O)c1ccc2c(c1)nc(SCc1ccccc1)n2NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1>>NS(=O)(=O)c1cc(C(=O)Nn2c(SCc3ccccc3)nc3cc(C(=O)O)ccc32)ccc1Cl -US20090209522A1,6,C[Si](C)(C)CCOCn1ccnc1CN1C(=O)c2ccccc2C1=O>>C[Si](C)(C)CCOCn1ccnc1CN -US20030096860A1,1,CCCCCCCCOc1c(O)c2ccc(O)cc2oc1=O.CCOC(=O)CCBr>>CCCCCCCCOc1c(O)c2ccc(OCCC(=O)OCC)cc2oc1=O -US08530648B2,1,ClCc1cccc(-c2cccnc2)c1.O=C1NCCCC12CCN(c1cnc3ccccc3n1)CC2>>O=C1N(Cc2cccc(-c3cccnc3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2 -US08299267B2,9,CC(C)(C)c1cccc(C=O)c1O.NO>>CC(C)(C)c1cccc(C=NO)c1O -US04618683,1,CI.COc1cc(C)c2c(c1OC)CCC1C(=O)NC(=O)C21>>COc1cc(C)c2c(c1OC)CCC1C(=O)N(C)C(=O)C21 -US05378689,6,COc1ccc(C[C@H](CC(=O)N2CCN(C)CC2)C(=O)OCc2ccccc2)cc1>>COc1ccc(C[C@H](CC(=O)N2CCN(C)CC2)C(=O)O)cc1 -US07396844B1,2,CCOC(=O)c1ccc(Nc2ccncc2)cc1.N#Cc1cccc(OCCN)c1>>N#Cc1cccc(OCCNC(=O)c2ccc(Nc3ccncc3)cc2)c1 -US20120202785A1,9,C[C@H](Nc1c(Cl)cnn(C)c1=O)c1nc2ccc(F)cc2n1-c1ccccc1>>C[C@H](Nc1ccnn(C)c1=O)c1nc2ccc(F)cc2n1-c1ccccc1 -US04025630,6,COC(=O)CCCN1CCOCC1>>O=C(O)CCCN1CCOCC1 -US20040048916A1,7,CC(C)CN1C(=O)c2cc(Cl)c(Cl)cc2C1=O>>CC(C)CN1C(=O)c2cc(Cl)c(Cl)cc2C1O -US20060058328A1,1,C=O.c1cncc(N2CCC3(CCCN3)C2)c1>>CN1CCCC12CCN(c1cccnc1)C2 -US07541464B2,6,CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1Cn1ccc2cc(OC)cnc21>>CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1Cn1ccc2cc(O)cnc21 -US20070093484A1,2,CCOC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1Cn1nnc(C)n1.NN1CCCCC1>>Cc1nnn(Cc2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)nc2C(=O)NN2CCCCC2)n1 -US04920223,9,CCn1cc(Br)nc(Br)c1=O.N>>CCn1cc(Br)nc(N)c1=O -US20120225854A1,1,COc1cccc(CC2CN(S(=O)(=O)c3cccs3)CCN2)n1.OC(c1ccc(Br)cc1)(C(F)(F)F)C(F)(F)F>>COc1cccc(CC2CN(S(=O)(=O)c3cccs3)CCN2c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)n1 -US20060183762A1,1,CCOC(=O)c1cc(F)c(SC)nc1Cl.NC1CC1>>CCOC(=O)c1cc(F)c(SC)nc1NC1CC1 -US20050020605A1,2,CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.Cn1ccc2ccc(C(=O)O)cc21>>CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3ccc4ccn(C)c4c3)CC2)CC1 -US07115640B2,2,CN(C)CCN.O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1>>CN(C)CCNC(=O)c1ccc(Cl)c([N+](=O)[O-])c1 -US08507521B2,1,COC(=O)CN.O=Cc1ccc(Br)cc1Cl>>COC(=O)CNCc1ccc(Br)cc1Cl -US04472383,1,CCOC(=O)CN.O=C1CCCC1>>CCOC(=O)CNC1CCCC1 -US20110257151A1,2,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(N2C(=O)OC[C@@H]2Cc2ccccc2)c1.NS(=O)(=O)C1CC1>>CC1(C)Cc2cc(C(=O)NS(=O)(=O)C3CC3)ccc2NC1c1cccc(N2C(=O)OC[C@@H]2Cc2ccccc2)c1 -US06891039B2,1,Fc1ccc(-c2nc3nc(Cl)ccc3n2-c2ccnc(NC3CCCC3)n2)cc1.NCc1ccccc1>>Fc1ccc(-c2nc3nc(NCc4ccccc4)ccc3n2-c2ccnc(NC3CCCC3)n2)cc1 -US05688791,7,O=[N+]([O-])c1cccnc1N1CCNCC1>>Nc1cccnc1N1CCNCC1 -US20100137353A1,8,OC/C=C/c1cccc(F)c1>>O=C/C=C/c1cccc(F)c1 -US08119627B2,2,CC(=O)Cl.Clc1ccc(Oc2ccccc2NC2CCNCC2)c(Cl)c1>>CC(=O)N1CCC(Nc2ccccc2Oc2ccc(Cl)cc2Cl)CC1 -US04230862,6,COc1ccc(C(=O)C2=C(c3ccccc3)CCc3ccccc32)cc1>>O=C(C1=C(c2ccccc2)CCc2ccccc21)c1ccc(O)cc1 -US08173650B2,1,Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1.O=C1CCOC1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN([C@@H]4CCOC4)C3)n(C)c2n1 -US20080132539A1,2,CC(C)(C)OC(=O)N[C@H](CCC(=O)O)C(=O)OCc1ccccc1.Nc1ccccc1Nc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCC(=O)Nc1ccccc1Nc1ccccc1)C(=O)OCc1ccccc1 -US20040048866A1,7,COC(=O)c1cccc(Oc2nn(Cc3ccccc3)c3ccccc23)n1>>OCc1cccc(Oc2nn(Cc3ccccc3)c3ccccc23)n1 -US20070225271A1,6,COc1cc2nc(NC3CCN(C(=O)OC(C)(C)C)CC3)nc(OC)c2cc1OC>>COc1cc2nc(NC3CCNCC3)nc(OC)c2cc1OC -US20070049581A1,2,CC(C)(C)OC(=O)N1CCN(C2CCNCC2)CC1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(C2CCN(C(=O)OCc3ccccc3)CC2)CC1 -US20090247559A1,7,NC(=O)c1nc2ccc(Br)cn2c1[N+](=O)[O-]>>NC(=O)c1nc2ccc(Br)cn2c1N -US07563815B2,6,COC(=O)c1ccc(CN(c2nc3cc(OC)ccc3n2C)C2CCC(C(C)(C)C)CC2)cc1>>COc1ccc2c(c1)nc(N(Cc1ccc(C(=O)O)cc1)C1CCC(C(C)(C)C)CC1)n2C -US06509329B1,6,CCOC(=O)c1ccnc(C#Cc2cc(OC)c(OC)c(OC)c2)c1>>COc1cc(C#Cc2cc(C(=O)O)ccn2)cc(OC)c1OC -US20130317057A1,1,N#Cc1ccc([N+](=O)[O-])c(F)c1.NC1CC1>>N#Cc1ccc([N+](=O)[O-])c(NC2CC2)c1 -US07541365B2,6,CCNC(=O)CN(Cc1ccc(Cl)cc1)C1CCN(C(=O)OC(C)(C)C)C1>>CCNC(=O)CN(Cc1ccc(Cl)cc1)C1CCNC1 -US20110212956A1,2,CC1NCCc2cncnc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2ncncc2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US04001244,2,CC(C)N(CCN)C(C)C.COc1ccc(C2c3cc(OC)c(OC)cc3CCN2C(=O)Cl)cc1>>COc1ccc(C2c3cc(OC)c(OC)cc3CCN2C(=O)NCCN(C(C)C)C(C)C)cc1 -US20140323305A1,1,CC(=O)CCl.Oc1ccn(-c2ccc(Cl)cc2)n1>>CC(=O)COc1ccn(-c2ccc(Cl)cc2)n1 -US20090023785A1,7,COC(=O)C1Cc2ccc(OC)cc2C1>>COc1ccc2c(c1)CC(CO)C2 -US20140296256A1,6,CC(C)(C)OC(=O)Nc1ccc(C23CC4CC(CC(C4)C2)C3)cc1>>Nc1ccc(C23CC4CC(CC(C4)C2)C3)cc1 -US20080176889A1,1,O=[N+]([O-])c1cccc(CCl)c1.OCCNCCO>>O=[N+]([O-])c1cccc(CN(CCO)CCO)c1 -US20030149054A1,3,CN(CCCOc1ccc(C=O)cc1)c1nc2ccccc2o1.O=C1CSC(=O)N1>>CN(CCCOc1ccc(C=C2SC(=O)NC2=O)cc1)c1nc2ccccc2o1 -US05719141,2,CC(=O)Cl.Oc1cnc2ccccc2c1>>CC(=O)Oc1cnc2ccccc2c1 -US06306891B1,6,CCOC(=O)C(=O)CC(=O)c1ccc(-c2ccccc2)n1Cc1ccc(F)cc1>>O=C(O)C(=O)CC(=O)c1ccc(-c2ccccc2)n1Cc1ccc(F)cc1 -US07495007B2,3,CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1C=O.O=C1Cc2ccc(Cl)cc2N1>>CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1C=C1C(=O)Nc2cc(Cl)ccc21 -US20090156578A1,1,CC(C)(C)[S@](N)=O.CCc1c(C(C)=O)oc2ccccc12>>CCc1c(C(C)=N[S@](=O)C(C)(C)C)oc2ccccc12 -US07122545B2,2,CC(=O)Cl.COc1ccc(N2CCOCC2)c2sc(-c3nc4c([nH]3)CCNCC4)nc12>>COc1ccc(N2CCOCC2)c2sc(-c3nc4c([nH]3)CCN(C(C)=O)CC4)nc12 -US20130310362A1,3,Brc1ncn2cnnc2c1-c1ccccc1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ncn3cnnc3c2-c2ccccc2)cc1 -US06897210B2,1,COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O.O=C1NCCN1CCO>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN1CCNC1=O -US20040054182A1,1,CC(C)(C)OC(=O)N1CCC(CCN)CC1.O=[N+]([O-])c1c(C(F)(F)F)nc2ccccc2c1Cl>>CC(C)(C)OC(=O)N1CCC(CCNc2c([N+](=O)[O-])c(C(F)(F)F)nc3ccccc23)CC1 -US07902367B2,1,CC(C)(C)OC(=O)N1CCCC(CI)C1.Sc1nc(-c2ccccc2)cs1>>CC(C)(C)OC(=O)N1CCCC(CSc2nc(-c3ccccc3)cs2)C1 -US06172061B2,7,COCC(COC)N(C)Cc1ccc([N+](=O)[O-])cc1>>COCC(COC)N(C)Cc1ccc(N)cc1 -US20150191439A1,1,COc1ccc2cc(C=O)[nH]c2c1.NC12CC3CC(CC(C3)C1)C2>>COc1ccc2cc(CNC34CC5CC(CC(C5)C3)C4)[nH]c2c1 -US20080146587A1,9,N.O=C(OCc1ccccc1)c1cc2c(Br)cccc2n1Cc1cccc(F)c1>>NC(=O)c1cc2c(Br)cccc2n1Cc1cccc(F)c1 -US20120208792A1,3,CC(C)N(C(=O)c1ccncc1B(O)O)C(C)C.COC(=O)c1cccc(Br)c1N>>COC(=O)c1cccc(-c2cnccc2C(=O)N(C(C)C)C(C)C)c1N -US20140005175A1,2,CC(C)(C(=O)O)c1ccc(S(=O)(=O)/C=C/C#N)cc1.CC(C)CN>>CC(C)CNC(=O)C(C)(C)c1ccc(S(=O)(=O)/C=C/C#N)cc1 -US20090036643A1,1,CCCCCCCCCCCCc1csc(-c2cc(CCCCCCCCCCCC)c(Br)s2)c1.C[Sn](C)(C)Cl>>CCCCCCCCCCCCc1csc(-c2cc(CCCCCCCCCCCC)c([Sn](C)(C)C)s2)c1 -US20140288045A1,2,CC(C)(C)OC(=O)N1CC(N2CCNCC2)C1.COc1cc(Cl)c(I)cc1NC(C)C(=O)O>>COc1cc(Cl)c(I)cc1NC(C)C(=O)N1CCN(C2CN(C(=O)OC(C)(C)C)C2)CC1 -US07655686B2,1,COC(=O)C1(CC=O)CCCN1C(=O)OC(C)(C)C.COC(=O)[C@H](C)N>>COC(=O)[C@H](C)NCCC1(C(=O)OC)CCCN1C(=O)OC(C)(C)C -US20140275011A1,2,COC(=O)[C@@H]1CCC[C@H](C(=O)O)C1.Nc1cc(-c2ccc3ncn(CC4CCOCC4)c3c2)c(Cl)cn1>>COC(=O)[C@H]1CCC[C@@H](C(=O)Nc2cc(-c3ccc4ncn(CC5CCOCC5)c4c3)c(Cl)cn2)C1 -US20120219593A1,1,CCOC(=O)C(C)Br.COC(=O)c1cc(Br)ccc1O>>CCOC(=O)C(C)Oc1ccc(Br)cc1C(=O)OC -US20150141406A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.NC(=O)c1cc(Br)cs1>>CC1(C)OB(c2csc(C(N)=O)c2)OC1(C)C -US07795283B2,2,CC(C)(C)OC(=O)N1CCC(N)CC1.CCOC(=O)c1nnc(Nc2ccccc2F)o1>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2nnc(Nc3ccccc3F)o2)CC1 -US20150005279A1,3,COC(=O)c1ccc(B(O)O)c2ccn(S(=O)(=O)c3ccc(C)cc3)c12.O=C1C=C(Br)CC1>>COC(=O)c1ccc(C2=CC(=O)CC2)c2ccn(S(=O)(=O)c3ccc(C)cc3)c12 -US06075029,1,BrCc1ccccc1.Cc1nc2c([nH]1)c(=O)[nH]c(=O)n2C>>Cc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 -US05183902,2,C=CCN.Cc1cccc(OC2CN(C(=O)Cl)C2)c1>>C=CCNC(=O)N1CC(Oc2cccc(C)c2)C1 -US20090197897A1,6,Cc1cccc(-c2noc([C@H]3CCCN(C(=O)OC(C)(C)C)C3)n2)n1>>Cc1cccc(-c2noc([C@H]3CCCNC3)n2)n1 -US08183262B2,3,CC1(C)OB(c2cccc(S(N)(=O)=O)c2)OC1(C)C.FC(F)(F)c1ccc(-c2cc(C(F)(F)F)cc(-c3cccc(Br)c3)n2)cc1>>NS(=O)(=O)c1cccc(-c2cccc(-c3cc(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)n3)c2)c1 -US06506911B2,6,COCc1c(OCc2ccccc2)c(=O)cc(C)n1C>>COCc1c(O)c(=O)cc(C)n1C -US04333940,1,CCCCCCCCCCCCCCCCNc1ccc(C(=O)O)c(F)c1.OCC(O)CI>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)OCC(O)CO)c(F)c1 -US05489691,7,CC1(C)O[C@H](CC#N)C[C@H](CC(=O)N(c2ccccc2)c2ccccc2)O1>>CC1(C)O[C@H](CCN)C[C@H](CC(=O)N(c2ccccc2)c2ccccc2)O1 -US20140371283A1,8,Cc1cc(C)cc(C(O)C(=O)c2cc(F)cc(F)c2)c1>>Cc1cc(C)cc(C(=O)C(=O)c2cc(F)cc(F)c2)c1 -US20130040931A1,3,CC1(C)OB(c2ccc3nc(N)c(N4CCOCC4)cc3c2)OC1(C)C.Cc1cccc(-c2nnc3ccccn23)c1Br>>Cc1cccc(-c2nnc3ccccn23)c1-c1ccc2nc(N)c(N3CCOCC3)cc2c1 -US20100173889A1,1,CCCCC1(N(C)C)CCNCC1.CN(CC=O)C(=O)OC(C)(C)C>>CCCCC1(N(C)C)CCN(CCN(C)C(=O)OC(C)(C)C)CC1 -US06265434B1,1,CC(C)[C@H](O)C(=O)OCc1ccccc1.C[SiH](C)OC([C@H]1CNC[C@@H]1c1ccccc1)C(C)(C)C>>CC(C)[C@H](C(=O)OCc1ccccc1)N1C[C@H](C(O[SiH](C)C)C(C)(C)C)[C@@H](c2ccccc2)C1 -US04297516,3,C#CCBr.O=C1CCCCC1>>C#CCC1(O)CCCCC1 -US06010716,6,CCCCCCC(CCCCCCCCCCC(=O)OCC(CC)CCCC)OC(C)=O>>CCCCCCC(O)CCCCCCCCCCC(=O)OCC(CC)CCCC -US07091357B2,3,COC(=O)CCCCC=O.c1ccc([P+](c2ccccc2)(c2ccccc2)C2CCCCC2)cc1>>COC(=O)CCCCC=C1CCCCC1 -US08557816B2,8,COc1ccc2c(Sc3ccccc3)ccnc2c1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2c(S(=O)c3ccccc3)ccnc2c1 -US20120065224A1,1,CC(=O)CCc1ccccc1.NNc1cc[nH]c(=O)c1>>CC(CCc1ccccc1)=NNc1cc[nH]c(=O)c1 -US20130217664A1,1,CCc1cc(-c2cn[nH]c2)ccc1N(C)c1cc2c(cn1)ncn2C.NC(=O)CBr>>CCc1cc(-c2cnn(CC(N)=O)c2)ccc1N(C)c1cc2c(cn1)ncn2C -US07666866B2,2,COc1ccc(C(=O)Nc2cnccc2N)cc1.COc1ccc(C(=O)O)c(OCCCNC(=O)OC(C)(C)C)c1>>COc1ccc(C(=O)Nc2cnccc2NC(=O)c2ccc(OC)cc2OCCCNC(=O)OC(C)(C)C)cc1 -US20130158040A1,3,Cc1cc(S(=O)(=O)N(C)C)ccc1B(O)O.Clc1ccccc1-c1cc2nc(Br)cnc2[nH]1>>Cc1cc(S(=O)(=O)N(C)C)ccc1-c1cnc2[nH]c(-c3ccccc3Cl)cc2n1 -US20100152445A1,2,Nc1ccc(N2CCC(O)(c3cccc(C(F)(F)F)c3)CC2)nc1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>O=C(Nc1ccc(N2CCC(O)(c3cccc(C(F)(F)F)c3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US20150274688A1,2,CCCCN(CCCC)CCCOc1ccc(C(=O)Cl)cc1.CNC>>CCCCN(CCCC)CCCOc1ccc(C(=O)N(C)C)cc1 -US07834051B2,1,CC1NC(=O)C(C)(C)C1=O.N#Cc1c(F)cc(Br)cc1F>>CC1C(=O)C(C)(C)C(=O)N1c1cc(F)c(C#N)c(F)c1 -US20150175623A1,1,CC#Cc1sc2ncnc(Cl)c2c1I.CCOC(=O)[C@H](O)Cc1ccccc1OC1CCCCO1>>CC#Cc1sc2ncnc(O[C@H](Cc3ccccc3OC3CCCCO3)C(=O)OCC)c2c1I -US20030073641A1,2,NC(CC(=O)O)c1ccccc1O.O=S(=O)(Cl)c1ccc2ccccc2c1>>O=C(O)CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1O -US06939874B2,1,CN1CCNCC1.COc1cc([N+](=O)[O-])cc(OCCCl)c1OC>>COc1cc([N+](=O)[O-])cc(OCCN2CCN(C)CC2)c1OC -US04252803,4,NNc1ccc(Br)cc1.O=CCCCCCl>>ClCCCc1c[nH]c2ccc(Br)cc12 -US05374606,6,CCSCc1c(Cl)ccc(C(=O)OC)c1SC>>CCSCc1c(Cl)ccc(C(=O)O)c1SC -US07338959B2,2,CN(c1ccc2c(c1)nc(N)n2C)c1ccnc(Nc2ccc(CS(C)(=O)=O)cc2)n1.O=C(O)c1ccccc1>>CN(c1ccc2c(c1)nc(NC(=O)c1ccccc1)n2C)c1ccnc(Nc2ccc(CS(C)(=O)=O)cc2)n1 -US06344462B1,6,CCOC(=O)c1cccn1-c1ccc(Cl)c(COc2cccc3c(-n4cccn4)cc(C)nc23)c1Cl>>Cc1cc(-n2cccn2)c2cccc(OCc3c(Cl)ccc(-n4cccc4C(=O)O)c3Cl)c2n1 -US20100305093A1,4,CCc1c(C(=O)N2CCOc3ccc(-c4ccc(N)c(N)c4)cc3C2)ccc(S(C)(=O)=O)c1F.O=C(O)CO>>CCc1c(C(=O)N2CCOc3ccc(-c4ccc5nc(CO)[nH]c5c4)cc3C2)ccc(S(C)(=O)=O)c1F -US08895497B2,7,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)N[C@H](CO)COCc1ccccc1 -US20100120810A1,7,COc1cc2cc(-c3cccc([N+](=O)[O-])c3)nc(C)c2cc1OC>>COc1cc2cc(-c3cccc(N)c3)nc(C)c2cc1OC -US20130274469A1,2,CC(C)(C)N.Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC(C)(C)C)cn1 -US07727997B2,8,C=CCSc1cccc(C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)CNC2(c3cccc(CC)c3)CC2)c1.O=C(OO)c1cccc(Cl)c1>>C=CCS(=O)c1cccc(C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)CNC2(c3cccc(CC)c3)CC2)c1 -US20150118186A1,6,COc1ccnc(-c2cnn3ccccc23)n1>>Oc1ccnc(-c2cnn3ccccc23)n1 -US08916560B2,6,COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCC[C@H]3CO)nc2c1>>O=C(O)c1ccc2nc(-c3ccccc3)c(N3CCC[C@H]3CO)nc2c1 -US20100298342A1,6,C[C@H]1C[C@]2(CCN1C(=O)OCc1ccccc1)C(=O)NC(=O)N2c1cccc(C#N)c1>>C[C@H]1C[C@]2(CCN1)C(=O)NC(=O)N2c1cccc(C#N)c1 -US20150191461A1,6,Cc1cc(Nc2nccc(OCCO[Si](C)(C)C(C)(C)C)n2)cc(-c2cnn(CCC(N)=O)c2)c1>>Cc1cc(Nc2nccc(OCCO)n2)cc(-c2cnn(CCC(N)=O)c2)c1 -US07375126B2,2,CCOC(C)=O.COc1cc2c(cc1OC)C(NC(=O)Nc1cccc3[nH]ncc13)CC2>>COc1cc2c(cc1OC)C(NC(=O)Nc1cccc3c1cnn3C(C)=O)CC2 -US20110112120A9,1,CCCc1nc(CC)n(-c2ccc(O)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OC1CCC(F)(F)CC1>>CCCc1nc(CC)n(-c2ccc(OC3CCC(F)(F)CC3)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)c1cc(-c2ccc(Cl)cc2F)on1>>CC(C)C[C@H]1CN(C(=O)c2cc(-c3ccc(Cl)cc3F)on2)[C@@H](CC(C)C)C(=O)N1 -US07432283B2,1,CCCC(=O)CCC.Cc1cc(C)c(N2CCCc3c2nn(C)c3N)c(Cl)c1>>CCCC(CCC)Nc1c2c(nn1C)N(c1c(C)cc(C)cc1Cl)CCC2 -US20070078155A1,1,Cc1ccc2ccnc(Cl)c2n1.Nc1ccc(Cl)cn1>>Cc1ccc2ccnc(Nc3ccc(Cl)cn3)c2n1 -US20090306139A1,4,NC(=S)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1.O=C(CBr)C1CC1>>O=C(N1CCOCC1)N1CC(c2ccc(OC(F)(F)F)cc2)CC(c2nc(C3CC3)cs2)C1 -US20110053910A1,1,CN(CCO)C(=O)c1ccc(Cl)nc1Cl>>CN1CCOc2nc(Cl)ccc2C1=O -US20100121049A1,7,COC(=O)c1cccc2c1Cc1c-2[nH]c(=O)c2ccccc12>>O=c1[nH]c2c(c3ccccc13)Cc1c(CO)cccc1-2 -US06136842,1,CI.COC(=O)C(Cc1cc2c(cc1Cl)OCO2)CN(C)C>>COC(=O)C(Cc1cc2c(cc1Cl)OCO2)C[N+](C)(C)C -US05210193,1,C=O.CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(c4ccc(Br)s4)C3)cc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)C(c4ccc(Br)s4)C3)cc21 -US20020035137A1,3,CCOC(=O)CP(=O)(OCC)OCC.COc1ccc(Br)c(C=O)c1>>CCOC(=O)/C=C/c1cc(OC)ccc1Br -US20130045975A1,1,CNCCN(C)C.COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)[nH]c2c1OCCCCCCCl>>COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)[nH]c2c1OCCCCCCN(C)CCN(C)C -US05763599,2,COc1ccc([N+](=O)[O-])c(CCO)c1.O=C(Cl)Cl>>COc1ccc([N+](=O)[O-])c(CCOC(=O)Cl)c1 -US07091211B2,8,CC(O)C1(CCO[Si](C)(C)C(C)(C)C)CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)C1(CCO[Si](C)(C)C(C)(C)C)CCN(C(=O)OC(C)(C)C)CC1 -US20120101137A1,1,CNCC(=O)N1CCCC1c1cc(C(=O)Nc2ncc(F)s2)c(C)s1.COC(=O)CCCCBr>>COC(=O)CCCCN(C)CC(=O)N1CCCC1c1cc(C(=O)Nc2ncc(F)s2)c(C)s1 -US20130045962A1,1,CNCc1ccncc1.Fc1c(Cl)nc(Cl)nc1Cl>>CN(Cc1ccncc1)c1nc(Cl)nc(Cl)c1F -US20060172988A1,6,CCOC(=O)c1cc(C#N)cc2ccsc12>>N#Cc1cc(C(=O)O)c2sccc2c1 -US20100239576A1,2,COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)OC(=O)[C@H](C)NC(=O)OCc5ccccc5)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 -US20130109665A1,2,NN1CCCCC1.O=C(O)c1cnc(C2CC2)c(OCC2CC2)n1>>O=C(NN1CCCCC1)c1cnc(C2CC2)c(OCC2CC2)n1 -US20090149468A1,9,CCOC(=O)CC(=O)c1ccnc(Cl)c1>>CC(=O)c1ccnc(Cl)c1 -US20100160302A1,1,N#C[C@@H]1CCCN1C(=O)CCl.NC12CC3CC1CC(O)(C3)C2>>N#C[C@@H]1CCCN1C(=O)CNC12CC3CC1CC(O)(C3)C2 -US20100069357A1,1,CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CCNC3)cc1.Cc1cc(Cl)nc(Cl)n1>>CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CCN(c2nc(C)cc(Cl)n2)C3)cc1 -US08476295B2,1,Cc1ccc(C=O)cc1.c1cc2[nH]ncc2cc1NC12CCC(CC1)NC2>>Cc1ccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2CC3)cc1 -US20030199553A1,7,COC(=O)c1ccc([N+](=O)[O-])c2c1OCCCO2>>COC(=O)c1ccc(N)c2c1OCCCO2 -US20130274240A1,6,CCOC(=O)c1ccccc1-c1ccc(Cl)cc1C>>Cc1cc(Cl)ccc1-c1ccccc1C(=O)O -US20060199817A1,8,OCc1ccc(Cl)c(I)c1F>>O=Cc1ccc(Cl)c(I)c1F -US04011331,2,CC1CCCC(C)N1CCN.CN=C=S>>CNC(=S)NCCN1C(C)CCCC1C -US20130237535A1,3,CC1(C)OB(c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)OC1(C)C.NC(=O)c1cnc2cc(Br)ccc2c1>>NC(=O)c1cnc2cc(-c3ccc(S(=O)(=O)N4CCC5(CC4)CN(C4CC4)C(=O)CO5)cc3)ccc2c1 -US20060063772A1,10,Cc1ncc(-c2cccc(Cl)c2)o1.O=C1CCC(=O)N1Br>>Clc1cccc(-c2cnc(CBr)o2)c1 -US20130345218A1,3,CC(C)(C)OC(=O)N[C@@H]1CCC[C@H](Nc2nc(Cl)c(C#N)cc2F)C1.Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(F)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3nc(N[C@H]4CCC[C@@H](NC(=O)OC(C)(C)C)C4)c(F)cc3C#N)c3cc(F)cnc32)cc1 -US20140107105A1,1,CC(C)(C)OC(=O)N1CCCNCC1.O=C1CCC1>>CC(C)(C)OC(=O)N1CCCN(C2CCC2)CC1 -US20120295924A1,6,CC(=O)Nc1nc(-c2ccc(C(F)(F)F)c(F)c2)c[nH]1>>Nc1nc(-c2ccc(C(F)(F)F)c(F)c2)c[nH]1 -US20010009916A1,2,COC(=O)Cl.CON1C(=O)[C@H](N)Cc2ccccc21>>COC(=O)N[C@@H]1Cc2ccccc2N(OC)C1=O -US07951805B2,1,CI.O=C(NCCC1CC1)c1ccc(N2CCC(C(=O)c3ccc(F)cc3)CC2)nn1>>CN(CCC1CC1)C(=O)c1ccc(N2CCC(C(=O)c3ccc(F)cc3)CC2)nn1 -US20140005213A1,1,CC(C)(C)OC(=O)N[C@H]1CCN([C@H](c2ccc(NN)nc2)C(F)(F)F)C1.CC(C)Oc1cc2nc(C=O)ccc2cc1F>>CC(C)Oc1cc2nc(/C=N/Nc3ccc([C@@H](N4CC[C@H](NC(=O)OC(C)(C)C)C4)C(F)(F)F)cn3)ccc2cc1F -US20060257987A1,6,CCc1ccc(OC)c(Oc2ccccc2C)c1>>CCc1ccc(O)c(Oc2ccccc2C)c1 -US04176116,2,CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](C)N.O=C(O)C1CCCCC1>>CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)C1CCCCC1 -US08304557B2,2,Cn1ncc(C(=O)O)c1Cl.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>Cn1ncc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)c1Cl -US07999132B2,2,CC(C)(C)OC(=O)c1ccc(Oc2ccccc2)cc1N.COc1ccccc1C(=O)O>>COc1ccccc1C(=O)Nc1cc(Oc2ccccc2)ccc1C(=O)OC(C)(C)C -US20070088044A1,1,CN1CCC(Oc2cc(O)cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c23)CC1.COCCBr>>COCCOc1cc(OC2CCN(C)CC2)c2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2c1 -US20080021071A1,3,CC(C)=O.O=Cc1ccc(-c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)cn1>>CC(=O)CC(O)c1ccc(-c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)cn1 -US20140121200A1,3,CC(C)(C)OC(=O)N1CC(O)CC(CNc2nc(Cl)cc3nccnc23)C1.OB(O)c1ccc(N2CCOCC2)cc1>>CC(C)(C)OC(=O)N1CC(O)CC(CNc2nc(-c3ccc(N4CCOCC4)cc3)cc3nccnc23)C1 -US06806265B2,6,c1ccc(COc2ccc(-c3ccncc3)cc2)cc1>>Oc1ccc(-c2ccncc2)cc1 -US20150259328A1,1,FCCBr.NC(=O)c1cnc(Nc2ccc(C3CCNCC3)cc2)nc1NC1CC1>>NC(=O)c1cnc(Nc2ccc(C3CCN(CCF)CC3)cc2)nc1NC1CC1 -US05567822,9,O=[N+]([O-])c1c(OC(F)(F)F)ccc2nc(Cl)sc12.[NH4+]>>Nc1nc2ccc(OC(F)(F)F)c([N+](=O)[O-])c2s1 -US04053312,2,CCCCCCCCCCCCCCCCS(=O)(=O)Cl.Nc1cccc2ccc(O)cc12>>CCCCCCCCCCCCCCCCS(=O)(=O)Nc1cccc2ccc(O)cc12 -US06818649B2,6,CCOc1cc(C2OCCO2)cc2c1OC(C)(C)C=C2C(C)(C)O>>CCOc1cc(C=O)cc2c1OC(C)(C)C=C2C(C)(C)O -US08137583B2,1,CCBr.OC1CCC(c2cccc(F)c2)CC1>>CCOC1CCC(c2cccc(F)c2)CC1 -US20100240702A1,7,C[C@H](Nc1ccccc1[N+](=O)[O-])C(=O)OC(C)(C)C>>C[C@H](Nc1ccccc1N)C(=O)OC(C)(C)C -US20090298820A1,1,Cn1cc(C=O)c2c(Br)ccnc21.Oc1ccccc1>>Cn1cc(C=O)c2c(Oc3ccccc3)ccnc21 -US08552039B2,9,COc1ccccc1C(=O)CN=[N+]=[N-]>>COc1ccccc1C(=O)CN -US20110092505A1,6,CC(C)(C)OC(=O)N1CCN(c2cc(CN)cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1>>NCc1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCNCC2)c1 -US04017621,6,CCc1ccc2c(c1)N(CC1CN(Cc3ccccc3)CCO1)c1ccccc1CC2>>CCc1ccc2c(c1)N(CC1CNCCO1)c1ccccc1CC2 -US05262433,2,O=C(O)Cn1nnnc1-c1ccsc1.OCCCCCO>>O=C(Cn1nnnc1-c1ccsc1)OCCCCCO -US20090069302A1,2,CN1CCOc2cc(S(=O)(=O)Cl)ccc21.CNCCN(C)S(=O)(=O)c1ccc(OC)c(OC)c1>>COc1ccc(S(=O)(=O)N(C)CCN(C)S(=O)(=O)c2ccc3c(c2)OCCN3C)cc1OC -US20070117836A1,2,CN(C)CCN1C(=O)c2cccc3cc(N)cc(c23)C1=O.O=C=NC(=O)CCl>>CN(C)CCN1C(=O)c2cccc3cc(NC(=O)NC(=O)CCl)cc(c23)C1=O -US05663024,1,Nc1ccc(CCO)cc1.O=C1c2ccccc2C(=O)c2c(Cl)cccc21>>O=C1c2ccccc2C(=O)c2c(Nc3ccc(CCO)cc3)cccc21 -US04963566,1,BrCc1cccc2cccnc12.CC(=O)[O-]>>CC(=O)OCc1cccc2cccnc12 -US20120214767A1,7,O=C(O)c1noc(-c2ccccc2)c1C(F)(F)F>>OCc1noc(-c2ccccc2)c1C(F)(F)F -US20110039838A1,6,C=CCOC(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1C(=O)OCC>>C=CCOC(=O)[C@@H]1CCNC[C@H]1C(=O)OCC -US05206235,2,CC(C)(CNC(=O)OCc1ccccc1)C(=O)O.N[C@@H]1CCc2ccccc2NC1=O>>CC(C)(CNC(=O)OCc1ccccc1)C(=O)N[C@@H]1CCc2ccccc2NC1=O -US05650411,1,CCC(Br)C(=O)c1ccc(Cl)cc1.COc1ccc(N2CCN(c3ncc(-n4cn[nH]c4=O)cn3)CC2)cc1>>CCC(C(=O)c1ccc(Cl)cc1)n1ncn(-c2cnc(N3CCN(c4ccc(OC)cc4)CC3)nc2)c1=O -US20020198388A1,2,CC(C)(CCC#N)CNC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C.O=C(Cl)OCc1ccccc1>>CC(C)(CCC#N)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1 -US20060172396A1,9,NO.O=C(O)C(=O)CC(O)(Cc1c[nH]c2ccccc12)C(=O)O>>O=C(O)C(CC(O)(Cc1c[nH]c2ccccc12)C(=O)O)=NO -US05631206,3,Brc1cccc(Br)n1.Cc1ccc(NC(=O)C(C)(C)C)c(B(O)O)c1>>Cc1ccc(NC(=O)C(C)(C)C)c(-c2cccc(Br)n2)c1 -US07235546B2,1,Cc1ccc2[nH]c(=O)oc(=O)c2c1.Fc1ccc(CBr)cc1>>Cc1ccc2c(c1)c(=O)oc(=O)n2Cc1ccc(F)cc1 -US20130190290A1,1,CC(C)(C)OC(=O)NCCBr.O=C(O)c1cc(O)cc(S(F)(F)(F)(F)F)c1>>CC(C)(C)OC(=O)NCCOc1cc(C(=O)O)cc(S(F)(F)(F)(F)F)c1 -US20110034469A1,2,O=C(N[C@@H]1CCOc2ccccc21)[C@@H]1CN2CCC[C@@H]2CN1.O=C(N[C@H](C(=O)O)C1CCC(F)(F)CC1)OCc1ccccc1>>O=C(N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCC(F)(F)CC1)OCc1ccccc1 -US20150005232A1,2,CN.COc1cc(C(=O)O)ccc1-c1cc(C(F)(F)F)cc2[nH]ncc12>>CNC(=O)c1ccc(-c2cc(C(F)(F)F)cc3[nH]ncc23)c(OC)c1 -US20060194969A1,6,CCOC(=O)c1cc(OCc2ccccc2)c2nc(C3CC3)n(C)c2c1>>CCOC(=O)c1cc(O)c2nc(C3CC3)n(C)c2c1 -US04435390,2,COCC(=O)O.C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO>>COCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C -US20110257151A1,6,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccc(F)c(NC(=O)C(C)C)c1)N2>>CC(C)C(=O)Nc1cc(C2Nc3ccc(C(=O)O)cc3CC2(C)C)ccc1F -US05854268,6,CC(C)(C)OC(=O)N1CC[C@@H](CSCc2ccccc2)C1>>c1ccc(CSC[C@@H]2CCNC2)cc1 -US20030027807A1,6,CCOC(=O)CCCN1CCn2nc(C(=O)OCc3ccccc3)cc2C1=O>>CCOC(=O)CCCN1CCn2nc(C(=O)O)cc2C1=O -US08486962B2,7,CN(C)CCOc1cccc([N+](=O)[O-])c1>>CN(C)CCOc1cccc(N)c1 -US20020049344A1,8,C=C(c1ccc(C(C)C)cc1)C(C)O>>C=C(C(C)=O)c1ccc(C(C)C)cc1 -US08518972B2,1,Fc1cccc(C2CCNCC2)c1.O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1>>O=C1CCC(N2Cc3c(OCc4ccc(CN5CCC(c6cccc(F)c6)CC5)cc4)cccc3C2=O)C(=O)N1 -US08524765B2,2,CCOC(=O)c1c(-c2ccc(Cl)cc2)csc1N.O=C(Cl)c1ccc(F)cc1>>CCOC(=O)c1c(-c2ccc(Cl)cc2)csc1NC(=O)c1ccc(F)cc1 -US05843957,1,CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(O)c2)c2cccnc21.OCCc1ccccn1>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCCc3ccccn3)c2)c2cccnc21 -US20130190295A1,1,BrCCc1ccccc1.Cc1ccc2[nH]c3c(c2c1)CCN(C)CC3>>Cc1ccc2c(c1)c1c(n2CCc2ccccc2)CCN(C)CC1 -US05457106,1,ClCCCCBr.Sc1ccncc1>>ClCCCCSc1ccncc1 -US08071650B2,2,CS(=O)(=O)Cl.N#CCc1ccccc1N>>CS(=O)(=O)Nc1ccccc1CC#N -US20030233015A1,1,C[C@@H](CO)c1ccc([N+](=O)[O-])cc1.O=C1NC(=O)c2ccccc21>>C[C@@H](CN1C(=O)c2ccccc2C1=O)c1ccc([N+](=O)[O-])cc1 -US20140288123A1,2,Cc1cc(C(=O)O)ccc1COc1ccccc1.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(COc3ccccc3)c(C)c2)c(O)n1 -US20070060754A1,2,CC(=O)Cl.CCCc1nc2c(N)nc3cc(OCCCCCCN)ccc3c2n1CCCCNS(C)(=O)=O>>CCCc1nc2c(N)nc3cc(OCCCCCCNC(C)=O)ccc3c2n1CCCCNS(C)(=O)=O -US20100125087A1,1,CC(C)(C)S(N)=O.N#Cc1ncccc1C(=O)c1cccc(OCCC(F)F)c1>>CC(C)(C)S(=O)N=C(c1cccc(OCCC(F)F)c1)c1cccnc1C#N -US20060063784A1,2,Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1.O=C(Cl)c1ccccc1>>O=C(Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1)c1ccccc1 -US08003677B2,6,CCOC(=O)c1cnc(N2CC3=C(CN(C(=O)OC(C)(C)C)C3)C2)s1>>CC(C)(C)OC(=O)N1CC2=C(C1)CN(c1ncc(C(=O)O)s1)C2 -US20150259366A1,1,COC(=O)c1ccc(N)cc1O.O=Cc1ccc(C2CCCCC2)cc1>>COC(=O)c1ccc(NCc2ccc(C3CCCCC3)cc2)cc1O -US20140364414A1,1,CCOC(=O)c1cc(CBr)nc2ccccc12.CCOP(OCC)OCC>>CCOC(=O)c1cc(CP(=O)(OCC)OCC)nc2ccccc12 -US20120328691A1,3,CCOC(=O)c1csc(Br)n1.COc1ccc(B(O)O)cc1>>CCOC(=O)c1csc(-c2ccc(OC)cc2)n1 -US20150284411A1,6,CC(C)(C)OC(=O)N1CCC(C#Cc2ccc(-c3nc4nc(O[C@@H]5CO[C@H]6[C@@H]5OC[C@H]6O[Si](C)(C)C(C)(C)C)n(COCC[Si](C)(C)C)c4cc3Cl)cc2)CC1>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(C#CC6CCNCC6)cc5)c(Cl)cc4n3COCC[Si](C)(C)C)CO[C@@H]21 -USRE043632E1,2,CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)OCCCO.O=C(Cl)c1cc(I)cc(I)c1I>>CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)OCCCOC(=O)c1cc(I)cc(I)c1I -US09073882B2,6,CC(C)(C)OC(=O)N1CCN(CCc2ccc3nonc3c2)CC1>>c1cc2nonc2cc1CCN1CCNCC1 -US06642381B2,1,C1CCNCC1.Nc1nc(N)c2nc(CCl)nnc2n1>>Nc1nc(N)c2nc(CN3CCCCC3)nnc2n1 -US20080076806A1,2,NC(c1ccccc1)c1cccc(Cl)c1.O=C(O)CNC(=O)c1ccc(F)cc1>>O=C(CNC(=O)c1ccc(F)cc1)NC(c1ccccc1)c1cccc(Cl)c1 -US08399436B2,7,O=C(O)c1ccc(I)cc1C(F)(F)F>>OCc1ccc(I)cc1C(F)(F)F -US20150210688A1,2,Cc1ccc(C(=O)O)cc1-c1[nH]nc(C)c1C.N#Cc1ccc(C2(F)CNC2)cc1>>Cc1ccc(C(=O)N2CC(F)(c3ccc(C#N)cc3)C2)cc1-c1[nH]nc(C)c1C -US20090054405A1,1,CC(=O)Nc1nc2ccc(-c3ccnc(Cl)n3)cc2s1.OCCCc1cccnc1>>CC(=O)Nc1nc2ccc(-c3ccnc(OCCCc4cccnc4)n3)cc2s1 -US20090143354A1,2,Cc1ccc2nc(Cl)ccc2c1N.O=C(Cl)CC1CCCCC1>>Cc1ccc2nc(Cl)ccc2c1NC(=O)CC1CCCCC1 -US04868327,9,NO.O=Cc1ccccc1>>ON=Cc1ccccc1 -US07115767B2,6,CCN(CC)c1ccc(NC(=O)C2(C(=O)OC(C)(C)C)CCc3ccccc3C2)cc1>>CCN(CC)c1ccc(NC(=O)C2(C(=O)O)CCc3ccccc3C2)cc1 -US20110269734A1,1,COC(=O)c1ccc(O)cc1C.C[C@H](CCOS(C)(=O)=O)C1CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)c1ccc(OCC[C@@H](C)C2CCN(C(=O)OC(C)(C)C)CC2)cc1C -US20050070592A1,1,BrCc1ccccc1.Cc1c(-c2ccccc2)[nH]c2cccc(Br)c12>>Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cccc(Br)c12 -US20120129840A1,1,C1CCNCC1.CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1N1CCCCC1 -US07345180B2,6,CC(C)(C)OC(=O)Cn1ccc2cc(C(=O)OCc3ccccc3)ccc21>>CC(C)(C)OC(=O)Cn1ccc2cc(C(=O)O)ccc21 -US20130079306A1,2,COc1ccc(CN(C)N)cc1.COc1ccccc1-c1cc(C(=O)O)c(C)o1>>COc1ccc(CN(C)NC(=O)c2cc(-c3ccccc3OC)oc2C)cc1 -US20150111944A1,2,CS/C(=N\C[Si](C)(C)C)c1ccc(C(=O)O)c(C)c1.NC1CSC1>>CSC(=NC[Si](C)(C)C)c1ccc(C(=O)NC2CSC2)c(C)c1 -US09090570B2,2,Nc1cnc(Br)cn1.O=C(Cl)c1c(F)cccc1F>>O=C(Nc1cnc(Br)cn1)c1c(F)cccc1F -US05789404,1,Fc1ccc(I)cc1.O=C(O)CCc1c[nH]c2ccc(Cl)cc12>>O=C(O)CCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 -US20080027112A1,1,C1COCCN1.COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCCCCCBr>>COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCCCCCN1CCOCC1 -US04888043,2,CCC(=O)C1=C(O)CC(c2c(C)cc(C)c(N)c2C)CC1=O.CS(=O)(=O)Cl>>CCC(=O)C1=C(O)CC(c2c(C)cc(C)c(NS(C)(=O)=O)c2C)CC1=O -US06964983B2,6,COC(=O)COc1ccc(SCc2cccc(OCc3ccc(C(F)(F)F)cc3)c2)c2c1CCC2>>O=C(O)COc1ccc(SCc2cccc(OCc3ccc(C(F)(F)F)cc3)c2)c2c1CCC2 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3scc(C)c23)cc1OC.c1c[nH]cn1>>COc1ccc(CNc2nc(-n3ccnc3)nc3scc(C)c23)cc1OC -US20060270706A1,7,COC(=O)Cn1nnnc1/C=C1\CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CCC1=O>>COC(=O)Cn1nnnc1/C=C1\CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CCC1O -US20080161294A1,6,CC(=O)OCCOc1ccc(C(=O)OCc2ccccc2)c(Cl)c1>>CC(=O)OCCOc1ccc(C(=O)O)c(Cl)c1 -US20150133428A1,2,CC1(CO)CC(F)(F)C1.CS(=O)(=O)Cl>>CC1(COS(C)(=O)=O)CC(F)(F)C1 -US20130090323A1,3,CC1(C)OB(c2cc(C(F)F)ccc2F)OC1(C)C.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1I>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1cc(C(F)F)ccc1F -US20100190825A1,6,COC1CCC(N2CCC(NC(=O)OC(C)(C)C)CC2)CC1>>CO[C@@H]1CC[C@@H](N2CCC(N)CC2)CC1 -US09120749B2,1,Nc1ccc(CN2CCCC2)cc1.O=C(c1cnc2ccc(Br)cc2c1Cl)C1CC1>>O=C(c1cnc2ccc(Br)cc2c1Nc1ccc(CN2CCCC2)cc1)C1CC1 -US20060205790A1,1,CC1(C)OCc2cc([C@@H]3CN(CCc4ccc5c(c4)O[C@H](CO)CO5)C(=O)O3)ccc2O1.NC(=O)Nc1cccc(CBr)c1>>CC1(C)OCc2cc([C@@H]3CN(CCc4ccc5c(c4)O[C@H](COCc4cccc(NC(N)=O)c4)CO5)C(=O)O3)ccc2O1 -US20050245563A1,3,Cc1c2c(=O)n(CCCNC(=O)OC(C)(C)C)c3ccc(Br)cc3c2nn1C1CCCCO1.N#Cc1ccc(B(O)O)cc1>>Cc1c2c(=O)n(CCCNC(=O)OC(C)(C)C)c3ccc(-c4ccc(C#N)cc4)cc3c2nn1C1CCCCO1 -US20060264415A1,8,O=C(CCl)Nc1ccc(CO)cc1>>O=Cc1ccc(NC(=O)CCl)cc1 -US20100048636A1,2,CC(C)(C)OC(=O)N[C@H](CO)CC1(F)CCCCC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@H](COS(C)(=O)=O)CC1(F)CCCCC1 -US06727264B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(O)c3ccc(F)cc3)CC2)c1.Oc1ccc(Cl)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(Oc3ccc(Cl)cc3)c3ccc(F)cc3)CC2)c1 -US08486943B2,1,CC(C)OC(=O)N[C@@H]1Cc2[nH]c3ccc(C#N)cc3c2C1.COc1ccccc1CCl>>COc1ccccc1Cn1c2c(c3cc(C#N)ccc31)C[C@H](NC(=O)OC(C)C)C2 -US20020156311A1,7,Cc1c(N(Cc2ccccc2)Cc2ccc(Oc3cccc(OC[C@@H]4CCC(=O)N4)c3)cc2)cccc1[N+](=O)[O-]>>Cc1c(N)cccc1N(Cc1ccccc1)Cc1ccc(Oc2cccc(OC[C@@H]3CCC(=O)N3)c2)cc1 -US06949542B2,2,CCCOc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F.Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)cc(C)n1>>CCCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cc(C)nc(C)c3)c2)cc1C(F)(F)F -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.Cc1ccnc2cc(O)ccc12>>COc1cc2c(Oc3ccc4c(C)ccnc4c3)ncnc2cc1OCC1CCN(C)CC1 -US20100210641A1,3,OB(O)c1ccoc1.OC1CCCC(Nc2ccc3ncc(-c4cc(F)nc(Cl)c4)n3c2)C1>>OC1CCCC(Nc2ccc3ncc(-c4cc(F)nc(-c5ccoc5)c4)n3c2)C1 -US08729061B2,2,CCC[C@H](N)C(=O)C(=O)NCc1ccccc1.O=C(O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1C(=O)C1(c2ncc(Cl)cc2F)CC1>>CCC[C@H](NC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1C(=O)C1(c2ncc(Cl)cc2F)CC1)C(=O)C(=O)NCc1ccccc1 -US05500405,2,CCOP(C)(=O)CO.O=S(=O)(Cl)c1ccccc1C(F)(F)F>>CCOP(C)(=O)COS(=O)(=O)c1ccccc1C(F)(F)F -US08598173B2,2,CCOC(=O)Nc1nc2ccc(Cl)cc2nc1OC.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>COc1nc2cc(Cl)ccc2nc1NC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1 -US04528298,8,COc1ccc(-c2nc(Sc3ccc(C)cc3)[nH]c2-c2ccc(OC)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nc(S(=O)c3ccc(C)cc3)[nH]c2-c2ccc(OC)cc2)cc1 -US20110178060A1,2,Cc1cc(N(C)C(=O)N(C)[C@@H]2CNC[C@H]2c2ccc(F)cc2)cc(C(F)(F)F)c1.O=C(O)C1CCC(F)(F)CC1>>Cc1cc(N(C)C(=O)N(C)[C@@H]2CN(C(=O)C3CCC(F)(F)CC3)C[C@H]2c2ccc(F)cc2)cc(C(F)(F)F)c1 -US04492792,1,CO.COC=C(C#N)C(OC)OC>>COC(OC)C(C#N)C(OC)OC -US07625932B2,1,CCI.N#Cc1ccc(O)c(Br)c1>>CCOc1ccc(C#N)cc1Br -US20150152114A1,6,CCCSc1nc(O)c(NC(C)=O)c(O)n1>>CCCSc1nc(O)c(N)c(O)n1 -US08242145B2,2,CNOC.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CON(C)C(=O)[C@H](C)NC(=O)OCc1ccccc1 -US20030144326A1,1,CS(=O)(=O)Nc1cc(C(O)CN)ccc1O.O=C1CCN(c2ccc(NS(=O)(=O)c3ccc(CC4SC(=O)NC4=O)cc3)cc2)CC1>>CS(=O)(=O)Nc1cc(C(O)CNC2CCN(c3ccc(NS(=O)(=O)c4ccc(CC5SC(=O)NC5=O)cc4)cc3)CC2)ccc1O -US04602030,8,Clc1ccc(SCC(Cn2ccnc2)OCc2ccc(Cl)cc2Cl)cc1.O=C(OO)c1cccc(Cl)c1>>O=S(CC(Cn1ccnc1)OCc1ccc(Cl)cc1Cl)c1ccc(Cl)cc1 -US20150141455A1,6,CCOC(=O)[C@]1(C)C[C@H]1c1ccccc1>>C[C@@]1(C(=O)O)C[C@H]1c1ccccc1 -US20120245178A1,9,ClCc1cc2ncccc2s1.N>>NCc1cc2ncccc2s1 -US20040030129A1,2,C1CSCCN1.COC1=C(OC)C(=O)C(Cc2ccccc2C=CC(=O)O)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccccc2C=CC(=O)N2CCSCC2)=C(C)C1=O -US20020068827A1,2,CC[C@H](NC(=O)c1c(OCCNC(=O)CCC(=O)O)c(-c2ccccc2)nc2ccccc12)c1ccccc1>>CC[C@H](NC(=O)c1c(OCCN2C(=O)CCC2=O)c(-c2ccccc2)nc2ccccc12)c1ccccc1 -US20120134959A1,3,CC1(C)OB(c2ccc(NC(=O)NC3CC3)cc2)OC1(C)C.CN(C)Cc1cc(N2C3CCC2COC3)nc(Cl)n1>>CN(C)Cc1cc(N2C3CCC2COC3)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 -US20090306041A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCc2cc(N(C)C)ccc2C1=O.Cn1cc(Br)cc(N)c1=O>>CC(=O)OCc1c(-c2cc(N)c(=O)n(C)c2)cccc1N1CCc2cc(N(C)C)ccc2C1=O -US05552399,5,C=CCNC.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C=CCN(C)C(=O)C(F)(F)F -US20090306115A1,3,C#Cc1cc(F)cc(Oc2cccnc2)c1.N#Cc1cccc(I)c1>>N#Cc1cccc(C#Cc2cc(F)cc(Oc3cccnc3)c2)c1 -US04753925,1,C1CNCCN1.CN(C)n1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21>>CN(C)n1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 -US06211199B1,1,COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5[nH]4)CC3)(c3ccc(F)c(F)c3)C2)cc(OC)c1OC.ClCc1ccc(Cl)s1>>COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5n4Cc4ccc(Cl)s4)CC3)(c3ccc(F)c(F)c3)C2)cc(OC)c1OC -US20110065681A1,1,O=C(O)c1cc(Br)cc(Br)c1.SC1CCCC1>>O=C(O)c1cc(Br)cc(SC2CCCC2)c1 -US07897618B2,2,Cn1cc(-c2ccc(F)cc2)c(C(=O)O)n1.c1cnc2cc(CC3CCCCN3)oc2c1>>Cn1cc(-c2ccc(F)cc2)c(C(=O)N2CCCCC2Cc2cc3ncccc3o2)n1 -US20110077399A1,1,CCn1cc(-c2ccc(Cl)cc2Cl)nc1/C=C/c1ccc(-c2ccc(O)cc2)cc1.COC(=O)CCCBr>>CCn1cc(-c2ccc(Cl)cc2Cl)nc1/C=C/c1ccc(-c2ccc(OCCCC(=O)OC)cc2)cc1 -US07750155B2,6,O=C(/C=C/c1cnc(N[C@@H]2CCN(CCCC3CCCCC3)C2)cn1)NOC1CCCCO1>>O=C(/C=C/c1cnc(N[C@@H]2CCN(CCCC3CCCCC3)C2)cn1)NO -US06310095B1,1,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1C=O.COC(=O)[C@H](CCSC)NC(=O)c1ccc(N)cc1-c1ccccc1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC[C@@H]2C[C@@H](O[Si](C)(C)C(C)(C)C)CN2C(=O)OC(C)(C)C)cc1-c1ccccc1 -US20100130496A1,1,Clc1cc(N2CCOCC2)nc(Cl)n1.NCCc1cccnc1>>Clc1cc(N2CCOCC2)nc(NCCc2cccnc2)n1 -US20020099007A1,6,COc1cccc(CCC(=O)NC(C)(c2ccc(C#N)c(F)c2)c2cncn2C)c1>>Cn1cncc1C(C)(NC(=O)CCc1cccc(O)c1)c1ccc(C#N)c(F)c1 -US20050038072A1,7,COc1c(Cl)cc(Cl)cc1C=O>>COc1c(Cl)cc(Cl)cc1CO -US20040138223A1,2,CC(C)c1ccc(NCc2ccc(N(C)C)cc2)cc1.CC(C)c1ccc2c(c1)C(C(=O)O)CCC2>>CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCCc3ccc(C(C)C)cc32)cc1 -US20110071197A1,1,COC(=O)c1cc(Oc2ccc([N+](=O)[O-])cn2)ccc1N.Fc1ccc(Br)cc1F>>COC(=O)c1cc(Oc2ccc([N+](=O)[O-])cn2)ccc1Nc1ccc(F)c(F)c1 -US04363912,7,C=C(c1cccnc1)c1c(C)[nH]c2ccccc12>>Cc1[nH]c2ccccc2c1C(C)c1cccnc1 -US08188098B2,1,CC(=O)N1CCN(c2ccc(O)cc2)CC1.CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1>>CC(=O)N1CCN(c2ccc(Oc3ncnc4c3cnn4C3CCN(C(=O)OC(C)(C)C)CC3)cc2)CC1 -US20140005213A1,6,CC(C)(C)OC(=O)N(CCF)[C@H]1CCN(C(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)N(CCF)[C@H]1CCNC1 -US08143251B2,4,COC(=O)c1ccc(-c2cnc(NN)nn2)cc1.O=CC1(c2ccc3ncccc3c2)CC1>>COC(=O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncccc6c5)CC4)n3n2)cc1 -US06995263B2,1,CC(C)(C)OC(=O)CBr.CC(C)(C)[Si](C)(C)Oc1ccc2cc[nH]c2c1>>CC(C)(C)OC(=O)Cn1ccc2ccc(O[Si](C)(C)C(C)(C)C)cc21 -US06774130B2,1,CC(=O)O[C@H](C)CCCCCl.Cn1c(N)cc(=O)[nH]c1=O>>CC(=O)O[C@H](C)CCCCn1c(=O)cc(N)n(C)c1=O -US05502191,4,COc1ccccc1C#N.[N-]=[N+]=[N-]>>COc1ccccc1-c1nnn[nH]1 -US06310070B1,2,CC(C)(C)c1ccc(Cn2cnc(N)c2C(N)=O)cc1.O=C(Cl)c1ccncc1>>CC(C)(C)c1ccc(Cn2cnc(NC(=O)c3ccncc3)c2C(N)=O)cc1 -US09078442B2,6,CCOC(=O)C1(C)CC(c2cc(Cl)cc(Cl)c2)=NO1>>CC1(C(=O)O)CC(c2cc(Cl)cc(Cl)c2)=NO1 -US20140234241A1,6,COc1cc(CNC(=O)c2cc(C34CC5CC(CC(C5)C3)C4)c(O)cc2O)cc(OC)c1>>COc1cc(O)cc(CNC(=O)c2cc(C34CC5CC(CC(C5)C3)C4)c(O)cc2O)c1 -US20090005380A1,6,COC(=O)c1ccc(O[C@@H]2CC[C@@H](C(=O)N3CCN(C(C)C)CC3)CC2)cc1>>CC(C)N1CCN(C(=O)[C@@H]2CC[C@@H](Oc3ccc(C(=O)O)cc3)CC2)CC1 -US04075001,4,N#CC(C(N)=S)=C(N)N1CCCC1>>N#Cc1c(N2CCCC2)nsc1N -US20140303161A1,3,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(I)c3c(N)ncnc32)C1.CC1(C)OB(c2ccc(Oc3cccc(F)c3F)cc2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4cccc(F)c4F)cc3)c3c(N)ncnc32)C1 -US20140343049A1,1,N#Cc1cc(C2=CC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)OC2)ccc1F.c1nc[nH]n1>>N#Cc1cc(C2=CC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)OC2)ccc1-n1cncn1 -US06797823B1,2,COc1cc2ncnc(Oc3ccc(N)c(C)c3)c2cc1OC.O=C=Nc1ccc(F)cc1F>>COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(C)c3)c2cc1OC -US05691335,2,O=C(Cl)c1cccc(Oc2ccccc2)c1.O=C1CN(c2ccccc2)C(=O)N1>>O=C1CN(c2ccccc2)C(=O)N1C(=O)c1cccc(Oc2ccccc2)c1 -US20100035918A1,1,COc1ccc(CCl)cc1.Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)[nH]c2=O)c1>>COc1ccc(Cn2c(C)c(-c3ccc4ncnn4c3)n(-c3cccc(C)c3)c2=O)cc1 -US20110212956A1,2,Fc1cccc2c1C(C(F)(F)F)NCC2.O=C(O)c1cc2ncc(Br)cn2n1>>O=C(c1cc2ncc(Br)cn2n1)N1CCc2cccc(F)c2C1C(F)(F)F -US20050107381A1,2,CCC[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)[O-].CCOC(=O)c1ccc(N)nc1>>CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ccc(C(=O)OCC)cn1 -US20070049587A1,7,COC(=O)C1CC(O)C(C#N)C1>>COC(=O)C1CC(O)C(CN)C1 -US20060040966A1,6,CC(C)(C)OC(=O)N1CCc2ncc([N+](=O)[O-])cc2C1>>O=[N+]([O-])c1cnc2c(c1)CNCC2 -US20040158074A1,3,COc1c(Cl)cc(B(O)O)cc1Cl.NS(=O)(=O)c1ccc(-c2cc(F)c(F)cc2Br)cc1>>COc1c(Cl)cc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)cc1Cl -US20100022612A1,3,O=Cc1cc(Br)co1.OB(O)/C=C/c1ccccc1>>O=Cc1cc(/C=C/c2ccccc2)co1 -US20090036495A1,1,COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2O)cc1.OCCc1c(F)cccc1F>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2OCCc2c(F)cccc2F)cc1 -US08501727B2,1,CN(C)CCCl.COc1ccc([C@@H]2Sc3c(cccc3OCc3ccccc3)NC(=O)[C@@H]2O)cc1>>COc1ccc([C@@H]2Sc3c(OCc4ccccc4)cccc3N(CCN(C)C)C(=O)[C@@H]2O)cc1 -US04269854,6,CCCc1c2c(c(OC)c3c(=O)cc(C(=O)OC)oc13)C(=O)CCC2>>CCCc1c2c(c(O)c3c(=O)cc(C(=O)OC)oc13)C(=O)CCC2 -US04847268,1,ClC1CCCc2cccnc21.Sc1ccc(Cl)cc1>>Clc1ccc(SC2CCCc3cccnc32)cc1 -US20130079373A1,2,CC(C(=O)O)c1ccc(CNS(C)(=O)=O)c(F)c1.CCCCCc1nc(C(F)(F)F)ccc1CN>>CCCCCc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(CNS(C)(=O)=O)c(F)c1 -US06645971B1,6,O=C1N(CCOC2CCCCO2)c2ccccc2C(c2ccccc2)N1C1CCN(Cc2ccccc2)CC1>>O=C1N(CCO)c2ccccc2C(c2ccccc2)N1C1CCN(Cc2ccccc2)CC1 -US20090270402A1,4,CC(C)c1nnc2ccc(C(Br)C(=O)c3ccc(F)cc3F)nn12.NC(=S)N1CCCCC1>>CC(C)c1nnc2ccc(-c3sc(N4CCCCC4)nc3-c3ccc(F)cc3F)nn12 -US20100274051A1,2,Nc1cc(C(F)(F)F)ccc1Cl.O=C(O)c1cc(Br)ccc1O>>O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1cc(Br)ccc1O -US07776875B2,1,CSCCl.O=Cc1cc(Cl)ccc1O>>CSCOc1ccc(Cl)cc1C=O -US20130137687A1,2,CC[C@H](N)C(=O)C(=O)NC1CC1.O=C(O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(N3CCOCC3)cc2Cl)CN1C(=O)C1(c2ccc(Cl)cc2)CC1>>CC[C@H](NC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(N3CCOCC3)cc2Cl)CN1C(=O)C1(c2ccc(Cl)cc2)CC1)C(=O)C(=O)NC1CC1 -US20070276009A1,2,NCc1ccccc1.O=C(O)c1ccc2[nH]c3c(c2c1)CCCC3=O>>O=C(NCc1ccccc1)c1ccc2[nH]c3c(c2c1)CCCC3=O -US20100120739A1,2,NNc1ccc(Cl)nn1.O=C(Cl)Cc1c(F)cc2ncccc2c1F>>O=C(Cc1c(F)cc2ncccc2c1F)NNc1ccc(Cl)nn1 -US05432182,1,CCCC(=O)c1cnc2c(O)cccc2c1Nc1ccc(F)cc1C.COCCCl>>CCCC(=O)c1cnc2c(OCCOC)cccc2c1Nc1ccc(F)cc1C -US07767691B2,1,Clc1cccc(OCCCBr)c1.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2>>OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCOc3cccc(Cl)c3)(CC1)C2 -US20110092461A1,2,CS(=O)(=O)c1ccc(C(=O)O)c(N)c1.Nc1ccc(Cl)c(-c2ccccn2)c1>>CS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(N)c1 -US06359181B1,6,COC(=O)CCC/C=C\C[C@H]1[C@@H](OC2CCCCO2)C[C@@H](OC2CCCCO2)[C@H]1C(O[SiH](C)C)C(C)(C)C>>C[SiH](C)OC([C@@H]1[C@H](OC2CCCCO2)C[C@H](OC2CCCCO2)[C@@H]1C/C=C\CCCC(=O)O)C(C)(C)C -US20050085520A1,1,COC(=O)c1cc(NC(=O)CCCBr)cc(C(=O)OC)c1>>COC(=O)c1cc(C(=O)OC)cc(N2CCCC2=O)c1 -US04816470,7,CC(C)NS(=O)(=O)Cc1ccc([N+](=O)[O-])cc1>>CC(C)NS(=O)(=O)Cc1ccc(N)cc1 -US20150141409A1,1,CCCCCCBr.O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1>>CCCCCCOC(=O)C(Cc1cc(=O)[nH]c2ccccc12)NC(=O)c1ccc(Cl)cc1 -US20080167310A1,1,CNc1ccccc1.Cc1oc(-c2ccc(Br)cc2)nc1CCOCc1ccccc1>>Cc1oc(-c2ccc(N(C)c3ccccc3)cc2)nc1CCOCc1ccccc1 -US05086055,6,CCNc1ccc(N2CCN(Cc3ccccc3)CC2)cc1>>CCNc1ccc(N2CCNCC2)cc1 -US20090227560A1,6,CCOC(=O)c1ncn([C@H]2CCCC[C@@H]2NC(=O)OC2CCC2)c1-c1ccccc1>>O=C(N[C@H]1CCCC[C@@H]1n1cnc(C(=O)O)c1-c1ccccc1)OC1CCC1 -US20110269774A1,1,CCn1nc(C)cc1N.CNC(=O)c1cc(F)ccc1Nc1cc(Cl)ncc1Cl>>CCn1nc(C)cc1Nc1cc(Nc2ccc(F)cc2C(=O)NC)c(Cl)cn1 -US20020022622A1,2,Cc1ccc2nc(-c3ccc(N)cc3)sc2c1.O=C(Cl)c1ccco1>>Cc1ccc2nc(-c3ccc(NC(=O)c4ccco4)cc3)sc2c1 -US05756505,1,CC(C)Cc1cc(C(=O)N2CCN(CC(C)C)CC2)ccc1O.Clc1ccc(CBr)cc1>>CC(C)Cc1cc(C(=O)N2CCN(CC(C)C)CC2)ccc1OCc1ccc(Cl)cc1 -US20140162997A1,6,COc1ccccc1-n1nc(OC2CN(C(=O)OC(C)(C)C)C2)cc1-c1ccc(Cl)cc1>>COc1ccccc1-n1nc(OC2CNC2)cc1-c1ccc(Cl)cc1 -US05155113,2,CC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)C[C@@H]1OCc1ccc(Cl)cc1.O=C(Cl)c1ccc(Cl)cc1>>CC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)n(C(=O)c3ccc(Cl)cc3)c2=O)C[C@@H]1OCc1ccc(Cl)cc1 -US20090325964A1,2,COc1ccc(C(=O)O)cc1C#Cc1ccccn1.O=C1CNCCN1>>COc1ccc(C(=O)N2CCNC(=O)C2)cc1C#Cc1ccccn1 -US20100069381A1,1,COc1ccc(-c2coc3ccc(-c4nnc(S)o4)cc23)cc1.COc1ccc(CCl)cc1F>>COc1ccc(-c2coc3ccc(-c4nnc(SCc5ccc(OC)c(F)c5)o4)cc23)cc1 -US20150238601A1,1,O=C(CCl)NC1CC1.Oc1ccc(F)c(Br)c1>>O=C(COc1ccc(F)c(Br)c1)NC1CC1 -US20140350032A1,6,CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)OC(C)(C)C)CC[C@@]54C)[C@]3(C)CC[C@@]2(/C=C/C(=O)N[C@@H](C)c2cccc(Cl)c2)CC1=O>>CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)O)CC[C@@]54C)[C@]3(C)CC[C@@]2(/C=C/C(=O)N[C@@H](C)c2cccc(Cl)c2)CC1=O -US05527919,2,CCCCC(=O)Cl.CCOC(=O)C(C#N)NCc1ccc(-c2ccccc2S(=O)(=O)N=CN(C)C)cc1>>CCCCC(=O)N(Cc1ccc(-c2ccccc2S(=O)(=O)N=CN(C)C)cc1)C(C#N)C(=O)OCC -US20110098296A1,1,CN(C)CCOc1cccc(N)c1.Cc1cc(-c2sc(N)nc2-c2cccc(NC(=O)c3c(F)cccc3F)c2)nc(Cl)n1>>Cc1cc(-c2sc(N)nc2-c2cccc(NC(=O)c3c(F)cccc3F)c2)nc(Nc2cccc(OCCN(C)C)c2)n1 -US06703526B1,1,CN(C)c1ccc(C=O)cc1.Cc1ccc(N)cc1O>>Cc1ccc(NCc2ccc(N(C)C)cc2)cc1O -US20130261106A1,1,CC(C)I.O=[N+]([O-])c1ccc(Cl)nc1O>>CC(C)Oc1nc(Cl)ccc1[N+](=O)[O-] -US20100137610A1,2,CCOC(=O)c1cc2cc(OCCCS(C)(=O)=O)cc(N)c2[nH]1.O=S(=O)(Cl)c1ccccn1>>CCOC(=O)c1cc2cc(OCCCS(C)(=O)=O)cc(NS(=O)(=O)c3ccccn3)c2[nH]1 -US20150175563A1,10,CCOC(=O)CC(=O)Cc1ccc(Cl)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)C(Br)C(=O)Cc1ccc(Cl)cc1 -US20130012703A1,3,Nc1cccc(B(O)O)c1.Nc1nc(Cl)nc2c(Br)csc12>>Nc1cccc(-c2csc3c(N)nc(Cl)nc23)c1 -US20100168087A1,1,CC1=NNS(=O)(=O)c2c1ccc(Cl)c2Cl.CI>>CC1=NN(C)S(=O)(=O)c2c1ccc(Cl)c2Cl -US20150251987A1,2,CCCCN.O=C(O)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1>>CCCCNC(=O)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1 -US20060106075A1,3,CC(=O)Cl.CCc1ccccc1CC>>CCc1ccc(C(C)=O)cc1CC -US04680300,1,ClCCCCCCCCOc1ccc2ccccc2c1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCCCCCCCOc1ccc2ccccc2c1 -US20140073620A1,3,C#Cc1ccccc1C(CC)C(N)=O.CC(C)(C)OC(=O)N1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(Cl)n3)cc2)CC1>>CCC(C(N)=O)c1ccccc1C#Cc1nc(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2)ncc1C(F)(F)F -US07910613B2,2,CCc1noc(-c2sc(N)nc2-c2ccccc2)n1.O=C(Cl)CC1CCCC1>>CCc1noc(-c2sc(NC(=O)CC3CCCC3)nc2-c2ccccc2)n1 -US20150210697A1,1,COc1ccc(CN(c2nc(Cl)nn3c(C#N)cnc23)C2CC2)cc1.N#Cc1cc(N)c(Cl)c(C2CCCC(=O)C2)c1>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(C4CCCC(=O)C4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1 -US20120142659A1,6,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC1>>CC(C)[C@H](N)C(=O)N1CCC1 -US05145858,1,CCOC(=O)CBr.Sc1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1>>CCOC(=O)CSc1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1 -US20090036450A1,9,CCOC(=O)c1oc(CCc2ccccc2)nc1C.N>>Cc1nc(CCc2ccccc2)oc1C(N)=O -US06703392B2,1,CCCBr.COc1ccc(CC2c3c(O)ccc(OC)c3CCN2CC(=O)NCc2ccccn2)cc1OC>>CCCOc1ccc(OC)c2c1C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NCc1ccccn1)CC2 -US20050165058A1,7,CC(NC=O)c1ccncc1>>CC(NC=O)C1CCNCC1 -US20050020587A1,1,CC(=O)N1CCC(NC(=O)c2cc(F)cnc2Cl)CC1.CSc1c(C)cc(O)cc1C>>CSc1c(C)cc(Oc2ncc(F)cc2C(=O)NC2CCN(C(C)=O)CC2)cc1C -US20020019527A1,6,COC(=O)c1ccc(COC(c2ccc(C#N)c(-c3ccccc3C)c2)c2cncn2C)cc1>>Cc1ccccc1-c1cc(C(OCc2ccc(C(=O)O)cc2)c2cncn2C)ccc1C#N -US07001897B2,6,CN(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OCc1ccccc1>>CNCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C -US20140291638A1,3,COc1cccc(B(O)O)c1.O=S(=O)(Oc1cccc2c3ccccc3c3ccccc3c12)C(F)(F)F>>COc1cccc(-c2cccc3c4ccccc4c4ccccc4c23)c1 -US20090004185A1,1,C1CNC1.O=C(Nc1ccc(CNc2nc(Cl)nc3ccccc23)cc1)c1ccc(F)cc1>>O=C(Nc1ccc(CNc2nc(N3CCC3)nc3ccccc23)cc1)c1ccc(F)cc1 -US08226929B2,1,CC1(C)C=Cc2c(O)c(C=O)cc([N+](=O)[O-])c2O1.CI>>COc1c(C=O)cc([N+](=O)[O-])c2c1C=CC(C)(C)O2 -US08436043B2,2,CCCCCCC(Nc1ccc(C(=O)O)cc1)c1cc2cc(Cl)ccc2n1C.CCOC(=O)CCN>>CCCCCCC(Nc1ccc(C(=O)NCCC(=O)OCC)cc1)c1cc2cc(Cl)ccc2n1C -US07666864B2,1,CC(O)(CN1CCCN(c2ncc(Br)cn2)CC1)Cn1cc([N+](=O)[O-])nc1Br>>CC1(CN2CCCN(c3ncc(Br)cn3)CC2)Cn2cc([N+](=O)[O-])nc2O1 -US20120108583A1,2,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(F)cccc4Cl)[nH]c23)O1.Nc1cc(C(F)(F)F)ccc1F>>CC1(C)Cc2c(c(C(=O)Nc3cc(C(F)(F)F)ccc3F)cc3nc(Nc4c(F)cccc4Cl)[nH]c23)O1 -US20150246922A1,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.N#Cc1cc(Br)c2c(c1)cc1n2CCCNC1=O>>N#Cc1cc(-c2ccc(N)nc2)c2c(c1)cc1n2CCCNC1=O -US20110130438A1,3,COc1cc(F)c(F)cc1B(O)O.Oc1ccc(I)cc1>>COc1cc(F)c(F)cc1-c1ccc(O)cc1 -US20110257208A1,1,O=Cc1ccncc1.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>c1ccc2ncc(Nc3ncnc4c3CN(Cc3ccncc3)C4)cc2c1 -US05962436,7,COC(=O)c1ccccc1-n1c(OC)nn(C)c1=O>>COc1nn(C)c(=O)n1-c1ccccc1CO -US20130190347A1,2,CCOC(=O)CCn1c2c(c3cc(C)ccc31)CN(C)CC2.NC1CCCC1>>Cc1ccc2c(c1)c1c(n2CCC(=O)NC2CCCC2)CCN(C)C1 -US04514214,2,COc1cc(OC)nc(N)n1.O=C=NS(=O)(=O)Oc1ccccc1-c1csnn1>>COc1cc(OC)nc(NC(=O)NS(=O)(=O)Oc2ccccc2-c2csnn2)n1 -US04066772,1,O=c1[nH]c2cc(Cl)ccc2n1C1CCNCC1.O=c1oc2ccccc2n1CCCCl>>O=c1oc2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1 -US08729078B2,1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2ccc(Br)nc21.CN1CCNCC1>>CC(C)[Si](C(C)C)(C(C)C)n1ccc2ccc(N3CCN(C)CC3)nc21 -US20130190307A1,2,CC(C)(C#N)c1ccc(C(=O)O)cc1.NNc1cnc2ccc(Br)cc2n1>>CC(C)(C#N)c1ccc(C(=O)NNc2cnc3ccc(Br)cc3n2)cc1 -US20060160879A1,7,CCCCc1ccc(-c2ccc3c(NC(=O)c4cccc([N+](=O)[O-])c4)c(C(=O)OCC)n(Cc4cccc(Cl)c4)c3c2)cc1>>CCCCc1ccc(-c2ccc3c(NC(=O)c4cccc(N)c4)c(C(=O)OCC)n(Cc4cccc(Cl)c4)c3c2)cc1 -US04439604,1,Cl[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1.Clc1ncnc2[nH]ccc12>>Clc1ncnc2c1ccn2[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 -US04898871,2,COCCN.COc1ccc2ccc(N3C(=O)c4ccccc4C3OCC(=O)O)nc2n1>>COCCNC(=O)COC1c2ccccc2C(=O)N1c1ccc2ccc(OC)nc2n1 -US20120101100A1,3,CCNC(=O)Nc1cc(Br)c(I)cn1.CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1cc(Br)c(-c2cncc(C(=O)OCC)c2)cn1 -US20140323486A1,7,O=[N+]([O-])c1ccc(CN2CCOCC2)cc1>>Nc1ccc(CN2CCOCC2)cc1 -US06887889B2,3,CN1CCC(C(=O)NCc2cc(Cl)cc(Cl)c2)(c2ccc(I)cc2)CC1.N#Cc1cccc(B(O)O)c1>>CN1CCC(C(=O)NCc2cc(Cl)cc(Cl)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 -US20050288273A1,2,CCOC(=O)Cl.COC(=O)CCCCc1cc(N)cc(F)c1>>CCOC(=O)Nc1cc(F)cc(CCCCC(=O)OC)c1 -US20100075965A1,6,CCOC(=O)CCCN1CCOCC1>>O=C(O)CCCN1CCOCC1 -US06329381B1,6,CCOCCOc1nc(N)c2nc(OC)n(Cc3ccccc3)c2n1>>CCOCCOc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1 -US04153725,6,COC(=O)CCC(C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O>>CC(CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O -US06727245B2,1,Clc1ncccn1.Nc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(Nc2ncccn2)c1 -US04511390,2,CC(C)C[C@H](N)CO.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CC(C)C[C@@H](CO)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 -US20060281771A1,2,Nc1ccc(N2CCCCC2)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Nc1ccc(N2CCCCC2)cc1)Oc1ccc([N+](=O)[O-])cc1 -US20100273771A1,1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCNC4)no2)cc1Cl.CCOC(=O)CCBr>>CCOC(=O)CCN1CCOc2c(cccc2-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)C1 -US06498151B2,7,CCOC(=O)CCc1ccc(Br)cc1>>OCCCc1ccc(Br)cc1 -US07232902B2,3,O=Cc1ccc(Br)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>O=Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US08513425B2,3,CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)C1.Clc1ccc(Br)cc1Cl>>CC(C)(C)OC(=O)N1CCC(C(=O)c2ccc(Cl)c(Cl)c2)C1 -US05312824,6,COc1ccnc(CSc2nc3ccc(F)cc3[nH]2)c1C>>Cc1c(O)ccnc1CSc1nc2ccc(F)cc2[nH]1 -US07799824B2,1,CCOC(=O)CCCBr.Oc1ccc(Cl)c(Cl)c1>>CCOC(=O)CCCOc1ccc(Cl)c(Cl)c1 -US20150182513A1,6,CC(=O)Oc1cnn(-c2ccc(Br)cc2)n1>>Oc1cnn(-c2ccc(Br)cc2)n1 -US07300935B2,7,COc1ccc(C)nc1[N+](=O)[O-]>>COc1ccc(C)nc1N -US20070155727A1,7,COC(=O)c1ccc(CC2(C#N)CCN(CC(=O)Nc3ccc(Oc4ccccc4)cc3)CC2)cc1>>COC(=O)c1ccc(CC2(CN)CCN(CC(=O)Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 -US20150031715A1,6,CCCOC(=O)[C@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)NC(=O)c1c(Cl)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc1Cl>>CCCOC(=O)[C@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)NC(=O)c1c(Cl)cc(O)cc1Cl -US20080221097A1,2,C1CCNCC1.Cn1cnc2c(Oc3cccc(Cl)c3)ncc(C(=O)O)c21>>Cn1cnc2c(Oc3cccc(Cl)c3)ncc(C(=O)N3CCCCC3)c21 -US07368578B2,1,COc1cc(C=O)ccc1O.Cc1oc(-c2cccnc2)nc1CCl>>COc1cc(C=O)ccc1OCc1nc(-c2cccnc2)oc1C -US20140323733A1,7,C[C@H](Cc1cccc(CC#N)c1)N[C@H](C)c1ccccc1>>C[C@H](Cc1cccc(CCN)c1)N[C@H](C)c1ccccc1 -US20070265259A1,6,CC(C)(C)OC(=O)N1CCCC1C(=O)Nc1ccc(N2CCOCC2=O)cc1>>O=C(Nc1ccc(N2CCOCC2=O)cc1)C1CCCN1 -US09126927B2,2,O=C(O)C1(c2ccc(-n3cccn3)cc2)CC1.O=C1OC2(CCNC2)c2ccncc21>>O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-n5cccn5)cc4)CC3)C2)c2ccncc21 -US20090036508A1,6,CC(C)(C)OC(=O)c1ccc(-c2ccc3[nH]nc(NC(=O)c4ccc(Cl)s4)c3c2)o1>>O=C(O)c1ccc(-c2ccc3[nH]nc(NC(=O)c4ccc(Cl)s4)c3c2)o1 -US04595696,1,CC(=O)Nc1ccc(O)cc1.CC(C=CC=C(C)C=CC1=C(C)CCCC1(C)C)=CC=CC(=O)O>>CC(=O)Nc1ccc(OC(=O)C=CC=C(C)C=CC=C(C)C=CC2=C(C)CCCC2(C)C)cc1 -US20040058965A1,1,CCI.O=Cc1cc(O)ccc1OCc1ccccc1>>CCOc1ccc(OCc2ccccc2)c(C=O)c1 -US20130150356A1,2,CC(C)COc1cc(N2CCNCC2)ncn1.Cn1nc(C(=O)O)cc1I>>CC(C)COc1cc(N2CCN(C(=O)c3cc(I)n(C)n3)CC2)ncn1 -US07087606B2,3,CC(=O)c1ccc(C)c(F)c1.CCOC(=O)C(=O)C(=O)OCC>>CCOC(=O)C(O)(CC(=O)c1ccc(C)c(F)c1)C(=O)OCC -US20080171743A1,3,C[C@H]1COCCN1c1cc(C(C)(C)S(=O)(=O)C2CC2)nc(Cl)n1.O=C(Nc1ccc(B(O)O)cc1)NC1CC1>>C[C@H]1COCCN1c1cc(C(C)(C)S(=O)(=O)C2CC2)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 -US04851535,1,C1CNCCN1.CCOC(=O)CC(=O)c1cc(F)c(Cl)nc1Nc1ccc(F)cc1F>>CCOC(=O)CC(=O)c1cc(F)c(N2CCNCC2)nc1Nc1ccc(F)cc1F -US07514567B2,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=C1O[C@]2(CN3CCC2CC3)CN1c1cc(Br)co1>>O=C1O[C@]2(CN3CCC2CC3)CN1c1cc(-c2ccccn2)co1 -US20130237519A1,2,CN1CCN(c2ccccc2CN)CC1.COC(=O)c1ccc(C)c(NC(=O)c2cnc3cc(Br)ccn23)c1>>Cc1ccc(C(=O)NCc2ccccc2N2CCN(C)CC2)cc1NC(=O)c1cnc2cc(Br)ccn12 -US06207693B1,7,COC(=O)c1cccc2[nH]c(COCc3ccccc3)cc12>>COC(=O)c1cccc2c1CC(COCc1ccccc1)N2 -US20070293532A1,1,O=[N+]([O-])c1cccnc1Cl.c1ccc(CNCc2ccccc2)cc1>>O=[N+]([O-])c1cccnc1N(Cc1ccccc1)Cc1ccccc1 -US20140162971A1,7,Cn1cc(-c2cc([N+](=O)[O-])ccc2Oc2ccc(F)c(F)c2)c2cc[nH]c2c1=O>>Cn1cc(-c2cc(N)ccc2Oc2ccc(F)c(F)c2)c2cc[nH]c2c1=O -US20120322788A1,1,CC(C)(C)[Si](C)(C)OCC(F)c1cccc(C=O)c1.CC(C)c1nc(C(=O)N2CCOC3(CCNCC3)C2)cs1>>CC(C)c1nc(C(=O)N2CCOC3(CCN(Cc4cccc(C(F)CO[Si](C)(C)C(C)(C)C)c4)CC3)C2)cs1 -US20100016279A1,1,FC(F)c1nnc2ccc(N3CCNCC3)nn12.O=Cc1cc(F)ccc1C(F)F>>Fc1ccc(C(F)F)c(CN2CCN(c3ccc4nnc(C(F)F)n4n3)CC2)c1 -US20120252801A1,2,CCN1CC(C)(C)OC(=O)C1CC(=O)O.Nc1ccc(Oc2ccccc2)cc1>>CCN1CC(C)(C)OC(=O)C1CC(=O)Nc1ccc(Oc2ccccc2)cc1 -US20150080549A1,1,CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1N=[N+]=[N-])C(=O)O.N#CCBr>>CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1N=[N+]=[N-])C(=O)OCC#N -US20100105727A1,2,CC(C)(C)C(=O)Cl.OCC1CCNCC1>>CC(C)(C)C(=O)N1CCC(CO)CC1 -US04237300,2,COC(=O)Cl.Nc1cn2cc(Sc3ccccc3)ccc2n1>>COC(=O)Nc1cn2cc(Sc3ccccc3)ccc2n1 -US08952004B2,1,ClCCN1CCCCC1.O=C(Nc1cc(Cl)cnc1N1CCNCC1)c1cccc(Cl)c1>>O=C(Nc1cc(Cl)cnc1N1CCN(CCN2CCCCC2)CC1)c1cccc(Cl)c1 -US05302724,2,Cc1ccsc1S(N)(=O)=O.O=C=Nc1ccc(Cl)cc1>>Cc1ccsc1S(=O)(=O)NC(=O)Nc1ccc(Cl)cc1 -US20070249670A1,2,COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1N)[C@@H](C)OC1CCC1.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)[C@@H](C)OC1CCC1 -US04621901,9,N#C[Cu].O=Cc1ccc(-c2ccc(Br)cc2)cc1>>N#Cc1ccc(-c2ccc(C=O)cc2)cc1 -US06992085B2,6,CCOC(=O)CCCC(=O)Nc1cc(OC)c(OC)c(OC)c1>>COc1cc(NC(=O)CCCC(=O)O)cc(OC)c1OC -US20080070935A1,1,Cc1c[nH]c2c1C(=O)CC(C)(C)C2.Cc1nc(N)nc2cc(F)ccc12>>Cc1cn(-c2ccc3c(C)nc(N)nc3c2)c2c1C(=O)CC(C)(C)C2 -US20050159479A1,2,CCCO.Cc1cc(O)c(C(=O)O)c(=O)o1>>CCCOC(=O)c1c(O)cc(C)oc1=O -US06432950B1,1,Cc1sc2nc(-c3ccno3)nc(Cl)c2c1Cl.NCCc1ccc2c(c1)OCO2>>Cc1sc2nc(-c3ccno3)nc(NCCc3ccc4c(c3)OCO4)c2c1Cl -US07795247B2,3,COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CC(=O)OC(C)(C)C)c2c1.O=Cc1ccoc1B(O)O>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3occc3C=O)n(CC(=O)OC(C)(C)C)c2c1 -US20060089371A1,6,COC(=O)[C@H](Cc1ccccc1)Nc1ncnc(-c2ccc(OCc3ccccc3)cc2)c1C=O>>O=Cc1c(N[C@@H](Cc2ccccc2)C(=O)O)ncnc1-c1ccc(OCc2ccccc2)cc1 -US04920116,7,CCCCOc1ccc(NC(=O)CCN(C)CCc2ccc(OC)c(OC)c2)cc1>>CCCCOc1ccc(NCCCN(C)CCc2ccc(OC)c(OC)c2)cc1 -US20070161681A1,7,CC(Oc1ccc(C#N)c(F)c1)C(=O)OC(C)(C)C>>CC(Oc1ccc(CN)c(F)c1)C(=O)OC(C)(C)C -US08193202B2,2,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.Nc1cccc(S(N)(=O)=O)c1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cccc(S(N)(=O)=O)c2)CC1 -US20070049632A1,3,Cc1cccc(B(O)O)c1.Cn1c2c(c(=O)n1-c1cccc(I)c1)C1CCC2(C)C1(C)C>>Cc1cccc(-c2cccc(-n3c(=O)c4c(n3C)[C@]3(C)CC[C@H]4C3(C)C)c2)c1 -US07906546B2,4,CC(C#N)(C1CCCC(=O)C1)S(=O)(=O)c1ccccc1.Cc1ccc(NN)cc1>>Cc1ccc2[nH]c3c(c2c1)CCC(C(C)(C#N)S(=O)(=O)c1ccccc1)C3 -US05352792,1,ClCBr.Cn1nnnc1S>>Cn1nnnc1SCCl -US20150099719A1,6,COC(=O)[C@H]1CC2CC2C[C@H]1C(=O)OCc1ccccc1>>COC(=O)[C@H]1CC2CC2C[C@H]1C(=O)O -US08022206B2,7,C=C(C)CC(O)c1c(Cl)ccc(F)c1Cl>>CC(C)CC(O)c1c(Cl)ccc(F)c1Cl -US05536734,1,CS(=O)(=O)OCC1=CCCCO1.Oc1ccccc1>>C1=C(COc2ccccc2)OCCC1 -US07842701B2,2,CS(N)(=O)=O.Cc1c(OCC(=O)O)cccc1-n1nc2c(c1N)c(=O)[nH]c1ccccc12>>Cc1c(OCC(=O)NS(C)(=O)=O)cccc1-n1nc2c(c1N)c(=O)[nH]c1ccccc12 -US09051342B2,2,COC(=O)c1ccc(NN)cc1.N#Cc1cccc(C(=O)O)c1>>COC(=O)c1ccc(NNC(=O)c2cccc(C#N)c2)cc1 -US08173652B2,2,Cc1onc(-c2ccccc2)c1COc1cc(C(=O)O)on1.NN1CCCC1>>Cc1onc(-c2ccccc2)c1COc1cc(C(=O)NN2CCCC2)on1 -US20080221161A1,6,COc1ccc2cc(CNCc3ccc(C(F)(F)F)cc3)c(-c3ccsc3)nc2c1>>Oc1ccc2cc(CNCc3ccc(C(F)(F)F)cc3)c(-c3ccsc3)nc2c1 -US08039493B2,2,CC(C)CNCc1ccc(-c2cccc(S(C)(=O)=O)c2)s1.O=S(=O)(Cl)c1cccc(Cl)c1F>>CC(C)CN(Cc1ccc(-c2cccc(S(C)(=O)=O)c2)s1)S(=O)(=O)c1cccc(Cl)c1F -US20090227575A1,7,CC(C)(C)OC(=O)n1ccc2c([N+](=O)[O-])cccc21>>CC(C)(C)OC(=O)n1ccc2c(N)cccc21 -US03968142,7,CC1(C(=O)O)CCC(=O)c2cc(C3CCCCC3)ccc21>>CC1(C(=O)O)CCCc2cc(C3CCCCC3)ccc21 -US20030149277A1,2,CN.O=C(Cl)c1ccc(-c2nc(-c3ccc4c(c3)OCO4)c(-c3ccccn3)[nH]2)cc1>>CNC(=O)c1ccc(-c2nc(-c3ccc4c(c3)OCO4)c(-c3ccccn3)[nH]2)cc1 -US06528677B1,3,CCCCCC1(C=O)CC2=C(C1)C(C)(C)CCC2(C)C.CCOC(=O)c1ccc(CP(=O)(OCC)OCC)cc1>>CCCCCC1(/C=C/c2ccc(C(=O)OCC)cc2)CC2=C(C1)C(C)(C)CCC2(C)C -US07671080B2,2,CC(O)(CCN)C(F)(F)F.N#Cc1ccc2c(c1)cc(C(=O)O)n2Cc1cccc(OC(F)(F)F)c1>>CC(O)(CCNC(=O)c1cc2cc(C#N)ccc2n1Cc1cccc(OC(F)(F)F)c1)C(F)(F)F -US20150166558A1,6,CNC(=O)Nc1cccc(C(Cn2c(=O)c3c(n(Cc4c(F)cccc4C(F)(F)F)c2=O)COC32CCN(Cc3ccc(C(F)(F)F)o3)CC2)NC(=O)OC(C)(C)C)c1>>CNC(=O)Nc1cccc(C(N)Cn2c(=O)c3c(n(Cc4c(F)cccc4C(F)(F)F)c2=O)COC32CCN(Cc3ccc(C(F)(F)F)o3)CC2)c1 -US09090599B2,2,COc1cc(CN)on1.Cc1ccc(-c2cc(C(=O)O)ncc2OCC(F)(F)F)cc1Cl>>COc1cc(CNC(=O)c2cc(-c3ccc(C)c(Cl)c3)c(OCC(F)(F)F)cn2)on1 -US07456218B2,9,CCOCCOc1cc(C)c(-c2cccc(COc3ccc(CCC(=O)O)c(F)c3)c2)c(C)c1.N>>CCOCCOc1cc(C)c(-c2cccc(COc3ccc(CCC(N)=O)c(F)c3)c2)c(C)c1 -US20150191439A1,1,Cc1nc(CCl)cs1.NC12CC3CC(CC(C3)C1)C2>>Cc1nc(CNC23CC4CC(CC(C4)C2)C3)cs1 -US20080076800A1,1,COC(=O)C(c1ccc(C#N)c(Br)c1)c1cc(OC)c(OC)c(OC)c1.N[C@H]1CC[C@H](O)CC1>>COC(=O)C(c1ccc(C#N)c(NC2CCC(O)CC2)c1)c1cc(OC)c(OC)c(OC)c1 -US20090137557A1,1,BrCc1ccccc1.Cc1nc(-c2cccc(O)c2F)n(CCc2ccccc2)c(=O)c1Br>>Cc1nc(-c2cccc(OCc3ccccc3)c2F)n(CCc2ccccc2)c(=O)c1Br -US20090118263A1,1,COC(=O)Cc1cccc(OCCN2CCOC3(CCNCC3)C2)c1.COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(CCl)cc3)c2n1>>COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(CN4CCC5(CC4)CN(CCOc4cccc(CC(=O)OC)c4)CCO5)cc3)c2n1 -US05013738,2,C=CC(CCCc1c(N)nc(N)nc1O)c1ccc(C(=O)O)cc1.COC(=O)CC[C@H](N)C(=O)OC>>C=CC(CCCc1c(N)nc(N)nc1O)c1ccc(C(=O)N[C@@H](CCC(=O)OC)C(=O)OC)cc1 -US20030083357A1,3,Brc1cc2c(c(C34CC5CC(CC(C5)C3)C4)c1)OCO2.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2cc3c(c(C45CC6CC(CC(C6)C4)C5)c2)OCO3)cc1 -US04022608,1,CCc1cccc(C)c1N.ClCC1OCCO1>>CCc1cccc(C)c1NCC1OCCO1 -US08318790B2,1,Cn1ccc2cc(NNC(N)=O)ccc21.O=Cc1cc(Br)c(OCc2ccccc2)cc1OCc1ccccc1>>Cn1ccc2cc(NNC(=O)N=Cc3cc(Br)c(OCc4ccccc4)cc3OCc3ccccc3)ccc21 -US20050065164A1,6,C[C@@H]1CN(Cc2ccccc2)CC[C@@H]1NC(=O)OC(C)(C)C>>C[C@@H]1CNCC[C@@H]1NC(=O)OC(C)(C)C -US20060189601A1,7,O=C(NCC(=O)N1CCCNCC1)OCc1ccccc1>>O=C(NCCN1CCCNCC1)OCc1ccccc1 -US20120178736A1,1,CC(C)C(O)C1CCNCC1.Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(O)C(C)C)CC3)n(C)c2n1 -US20130274469A1,2,C1COCCN1.Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)N2CCOCC2)cn1 -US20020006932A1,1,Cc1cc(CO)nn1C.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)NC(=O)N2c1ccccc1Cl>>Cc1cc(CN2C(=O)N(c3ccccc3Cl)C3(CCN(C(=O)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)C2=O)nn1C -US20100093814A1,6,CC(C)(C)OC(=O)N1CC[C@@H](Oc2ccc(C(F)(F)F)cc2C(=O)/N=c2\sc(C(C)(C)C)cn2C[C@H]2CCCO2)C1>>CC(C)(C)c1cn(C[C@H]2CCCO2)/c(=N/C(=O)c2cc(C(F)(F)F)ccc2O[C@@H]2CCNC2)s1 -US20080153813A1,1,CCCN.Clc1ccc2ncc(Br)n2n1>>CCCNc1ccc2ncc(Br)n2n1 -US08344029B2,9,N.O=C(NC(Cc1ccc(OC(F)(F)F)cc1)C(=O)O)c1ccc(OCCCC(F)(F)F)cc1>>NC(=O)C(Cc1ccc(OC(F)(F)F)cc1)NC(=O)c1ccc(OCCCC(F)(F)F)cc1 -US06949546B2,2,CC(C)(C)OC(=O)n1ncc2cc(N)ccc21.O=C(Cl)Oc1ccccc1>>CC(C)(C)OC(=O)n1ncc2cc(NC(=O)Oc3ccccc3)ccc21 -US20060161002A1,1,Nc1ccccc1Cl.O=C1CCCc2c1[nH]c1ccc(Br)cc21>>Clc1ccccc1NC1CCCc2c1[nH]c1ccc(Br)cc21 -US20110015407A1,4,CC(C)(C)OC(=O)C[C@H]1C[C@@H](CCN)OP(Cl)O1.CC(C)C(=O)CC(C(=O)c1ccc(F)cc1)c1ccccc1>>CC(C)c1cc(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OP(Cl)O1 -US20050085458A1,1,Cc1ccc2c(OCCBr)cccc2n1.O=C1CCc2ccc(OC3CCNCC3)cc2N1>>Cc1ccc2c(OCCN3CCC(Oc4ccc5c(c4)NC(=O)CC5)CC3)cccc2n1 -US20060079520A1,6,COC(=O)/C=C/c1cccc2c(C)c[nH]c12>>Cc1c[nH]c2c(/C=C/C(=O)O)cccc12 -US20090105252A1,5,CNc1cnoc1C.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1oncc1N(C)C(=O)C(F)(F)F -US20030083359A1,1,C=CCBr.O=Cc1cccc(O)c1>>C=CCOc1cccc(C=O)c1 -US20020099212A1,7,CCc1ccc(C(=O)O)cc1[N+](=O)[O-]>>CCc1ccc(C(=O)O)cc1N -US20070043076A1,3,O=C(CC(=O)Nc1cccc(C(F)(F)F)c1)Nc1cccc(C(F)(F)F)c1.O=Cc1c(Cl)cccc1Cl>>O=C(Nc1cccc(C(F)(F)F)c1)C(=Cc1c(Cl)cccc1Cl)C(=O)Nc1cccc(C(F)(F)F)c1 -US20040024215A1,3,COC(=O)c1cccc(F)c1OS(=O)(=O)C(F)(F)F.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)c1cccc(F)c1-c1ccc(C(F)(F)F)cc1 -US20050203087A1,6,COC(=O)c1sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c(Br)c1OCC(=O)OC(C)(C)C>>COC(=O)c1sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c(Br)c1OCC(=O)O -US05665575,6,CC(=O)OC(C)c1ccccc1>>C[C@H](O)c1ccccc1 -US06147097,1,C=CCBr.CC(C)c1nc(COCc2ccccc2)[nH]c1Sc1cccc(Cl)c1>>C=CCn1c(COCc2ccccc2)nc(C(C)C)c1Sc1cccc(Cl)c1 -US08334290B2,1,O=C(CBr)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1.Oc1cccc(F)c1>>O=C(COc1cccc(F)c1)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1 -US08809304B2,6,CCCCCCCSc1ccc(CCC(CO)(CO)NC(=O)OC(C)(C)C)cc1C(F)(F)F>>CCCCCCCSc1ccc(CCC(N)(CO)CO)cc1C(F)(F)F -US20060014750A1,3,Brc1ccccc1.CC1(C)OB(c2ccc(OC(=O)N3CCN4CCC3CC4)cc2)OC1(C)C>>O=C(Oc1ccc(-c2ccccc2)cc1)N1CCN2CCC1CC2 -US20150239891A1,6,CCOC(=O)c1cc2c(Nc3cc4sc(=O)[nH]c4cc3OC)ncnc2[nH]1>>COc1cc2[nH]c(=O)sc2cc1Nc1ncnc2[nH]c(C(=O)O)cc12 -US20040204449A1,7,COC(=O)C1CN(C(=O)OC(C)(C)C)Cc2ccc(OC)cc21>>COc1ccc2c(c1)C(CO)CN(C(=O)OC(C)(C)C)C2 -US07129268B2,6,CCOC(=O)COc1ccc(SCC=C(c2sccc2C)c2sccc2C)cc1C(F)(F)F>>Cc1ccsc1C(=CCSc1ccc(OCC(=O)O)c(C(F)(F)F)c1)c1sccc1C -US20090054405A1,3,CC1(C)OB(c2ccc3nc(NC(=O)C4CCCCC4)sc3c2)OC1(C)C.COc1ccc(S(=O)(=O)Nc2cc(Br)cnc2Cl)cc1>>COc1ccc(S(=O)(=O)Nc2cc(-c3ccc4nc(NC(=O)C5CCCCC5)sc4c3)cnc2Cl)cc1 -US07897776B2,2,CC(C)(C)c1cc(SC2CCNCC2)cc(C(C)(C)C)c1O.CCOC(=O)c1cnc(S(=O)(=O)Cl)[nH]1>>CCOC(=O)c1cnc(S(=O)(=O)N2CCC(Sc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)CC2)[nH]1 -US05395845,3,C#C[Mg+].O=Cc1csc(Br)n1>>C#CC(O)c1csc(Br)n1 -US07790720B2,1,CC1CCCN1.CCCN(CC1CC1)C(=O)c1oc(-c2ccc(OCCCCl)cc2)nc1C>>CCCN(CC1CC1)C(=O)c1oc(-c2ccc(OCCCN3CCCC3C)cc2)nc1C -US20110306626A1,6,CCOC(=O)CN1C(=O)C(c2ccccc2)=NC12CCCCC2>>O=C(O)CN1C(=O)C(c2ccccc2)=NC12CCCCC2 -US04740229,2,COC(=O)c1sccc1S(=O)(=O)N=C=O.COc1cc(C#N)nc(N)n1>>COC(=O)c1sccc1S(=O)(=O)NC(=O)Nc1nc(C#N)cc(OC)n1 -US20120149721A1,2,CCC(=O)Cl.COc1ccc(OCC2CC2)c(-c2ncnc3c(C(=O)N[C@H]4CC[C@@H](N)CC4)c(C)[nH]c23)c1>>CCC(=O)N[C@@H]1CC[C@H](NC(=O)c2c(C)[nH]c3c(-c4cc(OC)ccc4OCC4CC4)ncnc23)CC1 -US20120302549A1,3,NC1=N[C@@]2(CCc3ccc(Br)cc32)C(F)(F)CO1.OB(O)c1cc(Cl)cc(Cl)c1>>NC1=N[C@@]2(CCc3ccc(-c4cc(Cl)cc(Cl)c4)cc32)C(F)(F)CO1 -US20080058326A1,7,Cn1ncc2c(-c3ccc([N+](=O)[O-])cc3)cc(CS(C)(=O)=O)nc21>>Cn1ncc2c(-c3ccc(N)cc3)cc(CS(C)(=O)=O)nc21 -US08497264B2,1,CC(C)(C)CO.Fc1cccc(F)n1>>CC(C)(C)COc1cccc(F)n1 -US20150152108A1,6,CC(C)(C)OC(=O)N1CCCN(c2ccc3c(n2)N[C@H]2CCN3C2)CC1>>c1cc2c(nc1N1CCCNCC1)N[C@H]1CCN2C1 -US20090149445A1,3,CC1(C)OB(c2ccc3[nH]c(=O)[nH]c3c2)OC1(C)C.Fc1ccc2c(c1)COc1cc(F)ccc1C2=CBr>>O=c1[nH]c2ccc(C=C3c4ccc(F)cc4COc4cc(F)ccc43)cc2[nH]1 -US20110319439A1,7,COc1cc(Br)ccc1OCC(=O)C1CC1>>COc1cc(Br)ccc1OCC(O)C1CC1 -US04590188,1,CC(=O)O.COc1ccc([C@@H]2Sc3ccc(C)c(C)c3N(CCN(C)C)C(=O)[C@@H]2O)cc1>>COc1ccc([C@@H]2Sc3ccc(C)c(C)c3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1 -US03954753,2,Nc1nccnc1C(=O)c1ccccc1.O=C(Br)CBr>>O=C(CBr)Nc1nccnc1C(=O)c1ccccc1 -US06429207B1,2,NC1C2CC3CC(C2)CC1C3.O=C(O)c1cnc2ccccc2n1>>O=C(NC1C2CC3CC(C2)CC1C3)c1cnc2ccccc2n1 -US07612079B2,1,CC(C)n1cnc2c(NCc3ccccc3)nc(F)nc21.CC[C@@H](N)[C@H](C)O>>CC[C@@H](Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1)[C@H](C)O -US20040009965A1,1,CC(C)(O)c1csc(-c2cc3nccc(Cl)c3s2)n1.Cc1c(C(=O)NCC2CC2)c2ccc(O)cc2n1C>>Cc1c(C(=O)NCC2CC2)c2ccc(Oc3ccnc4cc(-c5nc(C(C)(C)O)cs5)sc34)cc2n1C -US07482375B2,1,CCC(=O)CBr.N#Cc1ccc(O)cc1>>CCC(=O)COc1ccc(C#N)cc1 -US04886822,7,COc1ccc(-c2ccccn2)c([N+](=O)[O-])c1>>COc1ccc(-c2ccccn2)c(N)c1 -US07935699B2,7,COC(=O)c1cccc(Cn2ccc([N+](=O)[O-])n2)c1>>COC(=O)c1cccc(Cn2ccc(N)n2)c1 -US20140200207A1,3,C[Si](C)(C)CCOCn1cc(I)c2c(NC3CCCC3)nc(Cl)nc21.OB(O)c1ccc(O)cc1>>C[Si](C)(C)CCOCn1cc(-c2ccc(O)cc2)c2c(NC3CCCC3)nc(Cl)nc21 -US06174889B1,1,CN1CCNCC1.Clc1cc2c(Nc3ccc4c(cnn4Cc4ccccc4)c3)ncnc2cn1>>CN1CCN(c2cc3c(Nc4ccc5c(cnn5Cc5ccccc5)c4)ncnc3cn2)CC1 -US20050239857A1,2,CC(C)C(NCC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O1)C(=O)OCc1ccccc1.O=C(Cl)c1ccc(F)cc1>>CC(C)C(C(=O)OCc1ccccc1)N(CC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O1)C(=O)c1ccc(F)cc1 -US20100160369A1,1,CI.N#Cc1cc(Cl)c(O)cc1Cl>>COc1cc(Cl)c(C#N)cc1Cl -US20130109661A1,1,CC(C)(C)OC(=O)N1CCN(CCOS(C)(=O)=O)CC1.CC1CCCN1c1cccc(Nc2cc(-c3cccc(O)c3)nn3ccnc23)n1>>CC1CCCN1c1cccc(Nc2cc(-c3cccc(OCCN4CCN(C(=O)OC(C)(C)C)CC4)c3)nn3ccnc23)n1 -US20110275797A1,1,CC(C)(C)[Si](C)(C)OCC=O.COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(C2CCNCC2)ccc1OCc1ccccc1>>COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(C2CCN(CCO[Si](C)(C)C(C)(C)C)CC2)ccc1OCc1ccccc1 -US20140080798A1,7,NC(=O)Cc1ccccc1C#Cc1nc(Cl)ncc1Cl>>NC(=O)Cc1ccccc1CCc1nc(Cl)ncc1Cl -US06452056B1,7,N#Cc1c(F)cccc1F>>NCc1c(F)cccc1F -US20110237565A1,1,CN1CCNCC1.Cc1cncc(Cl)n1>>Cc1cncc(N2CCN(C)CC2)n1 -US07566728B2,6,CCOC(=O)Cn1c(=O)n(C2CCN([C@@H]3Cc4cccc5cccc3c45)CC2)c2ccccc21>>O=C(O)Cn1c(=O)n(C2CCN([C@@H]3Cc4cccc5cccc3c45)CC2)c2ccccc21 -US20060135773A1,3,COc1ccc(B(O)O)cc1.COc1ccccc1S(=O)(=O)NCc1ccccc1Br>>COc1ccc(-c2ccccc2CNS(=O)(=O)c2ccccc2OC)cc1 -US20140336185A1,6,COC(=O)c1ccc(CC(=O)Nc2ccc(OC)cc2C(F)(F)F)cc1>>COc1ccc(NC(=O)Cc2ccc(C(=O)O)cc2)c(C(F)(F)F)c1 -US20090143354A1,1,N[C@H]1CCNC1.O=C(CCC1CCCCC1)Nc1c(Cl)ccc2nc(Cl)ccc12>>NC1CCN(c2ccc3c(NC(=O)CCC4CCCCC4)c(Cl)ccc3n2)C1 -US20120101100A1,3,CCNC(=O)Nc1cc(-c2nnc(-c3ccncc3)o2)c(Br)cn1.CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1cc(-c2nnc(-c3ccncc3)o2)c(-c2cncc(C(=O)OCC)c2)cn1 -US20100331293A1,2,COC(=O)CC(=O)OC.Nc1cc(F)cc(F)c1>>COC(=O)CC(=O)Nc1cc(F)cc(F)c1 -US07507740B2,6,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Nc3ncnc4ccn(CCOCCOC(=O)c5ccccc5)c34)cc2Cl)CC1>>O=C(OCCOCCn1ccc2ncnc(Nc3ccc(OC4CCNCC4)c(Cl)c3)c21)c1ccccc1 -US04640916,1,Cc1cccc2c1NC(=O)C(CCCBr)S2.Fc1ccccc1N1CCNCC1>>Cc1cccc2c1NC(=O)C(CCCN1CCN(c3ccccc3F)CC1)S2 -US20070167452A1,6,CC(C)(C)[Si](C)(C)OC[C@@H]1CC[C@H](CNC(=O)c2ccc(OCc3ccccc3)cc2)CC1>>O=C(NC[C@@H]1CC[C@H](CO)CC1)c1ccc(OCc2ccccc2)cc1 -US05891871,2,CO.O=C(O)Cc1ccc2c(c1)OCO2>>COC(=O)Cc1ccc2c(c1)OCO2 -US20140350040A1,3,C#CC[C@]1(NC(=O)OC(C)(C)C)CCN(C)C1=O.FC(F)(F)Oc1cccc(-c2ccnc(I)c2)c1>>CN1CC[C@](CC#Cc2cc(-c3cccc(OC(F)(F)F)c3)ccn2)(NC(=O)OC(C)(C)C)C1=O -US20090270402A1,1,CC(C)c1nnc2ccc(CC(=O)c3ccc(F)cc3F)nn12.NN1CCCC1=O>>CC(C)c1nnc2ccc(CC(=NN3CCCC3=O)c3ccc(F)cc3F)nn12 -US06518264B2,1,C1CCNCC1.CS(=O)(=O)C(=C1CN([C@@H](c2ccc(Cl)cc2)c2ccc(CCl)cc2)C1)c1cc(F)cc(F)c1>>CS(=O)(=O)C(=C1CN([C@@H](c2ccc(Cl)cc2)c2ccc(CN3CCCCC3)cc2)C1)c1cc(F)cc(F)c1 -US20050176941A1,1,BrCc1ccccc1.COCOC[C@]1(O)C[C@H](n2cc(C)c(=O)n(COCc3ccccc3)c2=O)O[C@]1(COCOC)COCc1ccccc1>>COCOC[C@]1(OCc2ccccc2)C[C@H](n2cc(C)c(=O)n(COCc3ccccc3)c2=O)O[C@]1(COCOC)COCc1ccccc1 -US08058045B2,1,CC(C)(C)OC(=O)N1CCCC(CNc2cc(Br)ncc2[N+](=O)[O-])C1.N#Cc1cnc(N)cn1>>CC(C)(C)OC(=O)N1CCCC(CNc2cc(Nc3cnc(C#N)cn3)ncc2[N+](=O)[O-])C1 -US20120015942A1,6,COc1ccc2c(c1)C[C@@H](C(=O)O)CC2>>O=C(O)[C@H]1CCc2ccc(O)cc2C1 -US04012413,2,CCC(CC(=O)O)N1C(=O)c2ccccc2C1=O.NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1>>CCC(CC(=O)NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1)N1C(=O)c2ccccc2C1=O -US20110257151A1,2,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(N2CCOC2=O)c1.NS(=O)(=O)C1CC1>>CC1(C)Cc2cc(C(=O)NS(=O)(=O)C3CC3)ccc2NC1c1cccc(N2CCOC2=O)c1 -US20150259354A1,6,NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn(-c2cc([N+](=O)[O-])ccc2COC2CCCCO2)c1N>>NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn(-c2cc([N+](=O)[O-])ccc2CO)c1N -US20110112100A1,2,NCc1cc(Br)ccc1N.O=C(O)c1ccc(Br)cn1>>Nc1ccc(Br)cc1CNC(=O)c1ccc(Br)cn1 -US20120088750A1,3,CCNC(=O)Nc1nc2cc(OS(=O)(=O)C(F)(F)F)cc(-c3ccccn3)c2s1.CCOC(=O)C1(C)Oc2cc(B3OC(C)(C)C(C)(C)O3)cnc2NC1=O>>CCNC(=O)Nc1nc2cc(-c3cnc4c(c3)OC(C)(C(=O)OCC)C(=O)N4)cc(-c3ccccn3)c2s1 -US20140038941A1,2,CC(C)(O)CN.O=C(O)c1cc(Cl)n2c(CC3CCC(F)(F)CC3)c(C(F)(F)F)nc2c1>>CC(C)(O)CNC(=O)c1cc(Cl)n2c(CC3CCC(F)(F)CC3)c(C(F)(F)F)nc2c1 -US04163112,1,COC(CCl)OC.Cc1cc(O)cc(O)c1>>COC(COc1cc(C)cc(O)c1)OC -US20130059846A1,6,Cc1ccc(-c2noc(C3(NC(=O)OC(C)(C)C)CC3)n2)cc1NC(=O)c1cnc2ccccn12>>Cc1ccc(-c2noc(C3(N)CC3)n2)cc1NC(=O)c1cnc2ccccn12 -US20090291940A1,1,Cc1cc(C)nc(N)c1.O=C1CCN(Cc2ccccc2)C1>>Cc1cc(C)nc(NC2CCN(Cc3ccccc3)C2)c1 -US04794108,7,COC(=O)[C@@H]1[C@H](NC(=O)OC(C)(C)C)C(=O)N1OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H]1C(=O)N(OCc2ccccc2)[C@@H]1CO -US20080262052A1,1,CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1CO.N#Cc1ccc(F)cc1C(F)(F)F>>CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc(C#N)c(C(F)(F)F)c1 -US20110178056A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCc2c(Br)cccc21>>CC(C)(C)OC(=O)N[C@@H]1CCc2c(Br)cccc21 -US08217177B2,3,CC1(C)OB(c2ccc(CO)c(Cl)c2)OC1(C)C.Clc1ccc2nnc(Cc3ccc4ncccc4c3)n2n1>>OCc1ccc(-c2ccc3nnc(Cc4ccc5ncccc5c4)n3n2)cc1Cl -US06080773,6,C=CCC(C)(C(=O)OCC)c1ccccc1-c1noc2ccccc12>>C=CCC(C)(C(=O)O)c1ccccc1-c1noc2ccccc12 -US20130197039A1,1,COCC(=O)COc1ccc(F)cc1.N>>COCC(N)COc1ccc(F)cc1 -US20100317680A1,1,CN(C)C(=O)CCl.O=[N+]([O-])c1cn[nH]c1>>CN(C)C(=O)Cn1cc([N+](=O)[O-])cn1 -US08273740B2,6,CCOC(=O)CCCCCSc1nc2ccccc2n1CC(=O)OC(C)(C)C>>CCOC(=O)CCCCCSc1nc2ccccc2n1CC(=O)O -US07273865B2,2,COc1cnc(N2CCOCC2)c2sc(N)nc12.O=C(Cl)c1ccc(CCl)cc1>>COc1cnc(N2CCOCC2)c2sc(NC(=O)c3ccc(CCl)cc3)nc12 -US20140128390A1,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1ncnc2cc(-c3cnn(CCN4CCOCC4)c3)sc12>>CC(C)(C)OC(=O)N1CCN(c2ncnc3cc(-c4cnn(CCN5CCOCC5)c4)sc23)CC1 -US08519135B2,8,O=S(=O)(Nc1cc(Cl)cnc1C(O)c1ccncc1)c1ccc(Cl)c(C(F)(F)F)c1>>O=C(c1ccncc1)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20100160379A1,1,O=Cc1ccc(F)c(F)c1.OCc1ccccn1>>O=Cc1ccc(OCc2ccccn2)c(F)c1 -US06441017B1,6,CC(C)(C)OC(=O)N[C@@H]1CCN(c2cccc3ccc(O[Si](C)(C)C(C)(C)C)cc23)C1>>CC(C)(C)OC(=O)N[C@@H]1CCN(c2cccc3ccc(O)cc23)C1 -US07884210B2,6,CCOC(=O)CSc1cnc(NC(=O)N(CC2CCCC2)c2cccc(C(=O)N(C)C)c2)s1>>CN(C)C(=O)c1cccc(N(CC2CCCC2)C(=O)Nc2ncc(SCC(=O)O)s2)c1 -US20100261755A1,2,COC(=O)C1CCNC(Cc2ccc(OC(F)(F)F)cc2)C1.COC(=O)Cl>>COC(=O)C1CCN(C(=O)OC)C(Cc2ccc(OC(F)(F)F)cc2)C1 -US20100292212A1,1,O=[N+]([O-])c1ccc(F)cc1.OC1CCOC1>>O=[N+]([O-])c1ccc(OC2CCOC2)cc1 -US20150025070A1,2,O=C(O)CN1CCC(C(=O)c2ccc(F)cc2)CC1.O=c1[nH]c(CNCc2ccc(F)cc2F)nc2c1COCC2>>O=C(c1ccc(F)cc1)C1CCN(CC(=O)N(Cc2nc3c(c(=O)[nH]2)COCC3)Cc2ccc(F)cc2F)CC1 -US20080194549A1,9,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN=[N+]=[N-])C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN)C(C)C)ccc1OC -US04981992,7,CCOC(=O)NCC(C(C)=O)C(=O)OCC>>CCOC(=O)NC[C@H](C(=O)OCC)[C@@H](C)O -US05447957,2,CCC(C)(C)c1ccc(Oc2ccc(C(F)(F)F)cc2N)c(C(=O)[O-])c1.O=C=Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCC(C)(C)c1ccc(Oc2ccc(C(F)(F)F)cc2NC(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(C(=O)[O-])c1 -US20090105232A1,3,C=C[Mg+].COc1ccc2nccc(Br)c2c1>>C=Cc1ccnc2ccc(OC)cc12 -US20070270408A1,2,CNC1CCCCC1.COC(=O)c1cc2nc(C)cc(-c3ccccc3)n2n1>>Cc1cc(-c2ccccc2)n2nc(C(=O)N(C)C3CCCCC3)cc2n1 -US07138425B2,7,C=CCOc1ccc([N+](=O)[O-])cc1-c1nc2cc(-c3ccccc3)ccc2o1>>C=CCOc1ccc(N)cc1-c1nc2cc(-c3ccccc3)ccc2o1 -US20120252789A1,1,CC(=O)OCCCCBr.CC1(C)CCC(C)(C)c2cc(-c3cccc(N4CCCNCC4)n3)ccc21>>CC(=O)OCCCCN1CCCN(c2cccc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)n2)CC1 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)C#Cc1ccc(Cl)cc1>>CC(C)CC1CN(C(=O)C#Cc2ccc(Cl)cc2)C(CC(C)C)C(=O)N1 -US04010177,1,C#CCN.O=[N+]([O-])c1ccc2c(c1)C(c1ccccc1Cl)=NCc1nnc(CBr)n1-2>>C#CCNCc1nnc2n1-c1ccc([N+](=O)[O-])cc1C(c1ccccc1Cl)=NC2 -US08486967B2,6,CC(C)(C)OC(=O)NN1CC(O)CC(c2ccc(F)cc2Cl)C1=O>>NN1CC(O)CC(c2ccc(F)cc2Cl)C1=O -US20120142681A1,1,CC(=O)c1ccc2nnc(C(F)(F)c3ccc4ncccc4c3)n2n1.NNC(N)=O>>C/C(=N\NC(N)=O)c1ccc2nnc(C(F)(F)c3ccc4ncccc4c3)n2n1 -US20120225862A1,2,CC(C)(C)c1ccc(S(=O)(=O)NCc2ccc(C(=O)O)cc2)cc1.Nc1ccc(F)nc1>>CC(C)(C)c1ccc(S(=O)(=O)NCc2ccc(C(=O)Nc3ccc(F)nc3)cc2)cc1 -US05229516,6,CCOC(=O)C(C)c1ccc2c(c1)[nH]c1ccc(O)cc12>>CC(C(=O)O)c1ccc2c(c1)[nH]c1ccc(O)cc12 -US20150031674A1,3,CSc1ncc2cc(-c3ccc(Br)cc3Cl)c(=O)n(C[C@H]3CN(C(=O)OC(C)(C)C)CCO3)c2n1.Cc1nc(Br)cs1>>CSc1ncc2cc(-c3ccc(-c4csc(C)n4)cc3Cl)c(=O)n(C[C@H]3CN(C(=O)OC(C)(C)C)CCO3)c2n1 -US08735584B2,1,COc1ccc(OC)c(N)c1.O=c1[nH]c2nccc(Cl)c2c2ccccc12>>COc1ccc(OC)c(Nc2ccnc3[nH]c(=O)c4ccccc4c23)c1 -US20040122244A1,2,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2)=C(C)C1=O -US06806273B1,1,Clc1nc(SCc2ccccc2)nc2nc(Br)sc12.NCCCO>>OCCCNc1nc2nc(SCc3ccccc3)nc(Cl)c2s1 -US04557753,1,CC(=O)c1ccc(CBr)cc1.Cn1ncc(C(=O)c2ccc(Cl)cc2Cl)c1O>>CC(=O)c1ccc(COc2c(C(=O)c3ccc(Cl)cc3Cl)cnn2C)cc1 -US20140179926A1,1,COCCBr.C[C@]1(CO)CCCN(C[C@H]2COc3ccccc3O2)C1>>COCCOC[C@@]1(C)CCCN(C[C@H]2COc3ccccc3O2)C1 -US20150266895A1,1,COc1ccccc1N.Clc1cc2c(cn1)c(I)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1ccccc1Nc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)ncc12 -US20020072516A1,1,CC(C)(C)OC(=O)NCCCCO.COCOc1c(C(=O)OC)c(O)cc2ccccc12>>COCOc1c(C(=O)OC)c(OCCCCNC(=O)OC(C)(C)C)cc2ccccc12 -US05244863,1,CC(C)CC(=O)Cl.CCC1=[SH]C(=N)N(c2cccc(C(F)(F)F)c2)C1>>CCC1=[SH]C(=NC(=O)CC(C)C)N(c2cccc(C(F)(F)F)c2)C1 -US08604015B2,1,O=C(CCl)c1ccccc1.O=C(N[C@H]1CN2CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1>>O=C(N[C@H]1C[N+]2(CC(=O)c3ccccc3)CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1 -US20100004271A1,3,C=CC(=O)OCC.O=[N+]([O-])c1ccc(Oc2c(Br)cc(OS(=O)(=O)C(F)(F)F)cc2Br)cc1>>CCOC(=O)/C=C/c1cc(Br)c(Oc2ccc([N+](=O)[O-])cc2)c(Br)c1 -US08895547B2,1,CC1(C)OC(N[C@@H](CCO)c2ccccc2)=NS(=O)(=O)C1c1ccc(O)cc1.CI>>COc1ccc(C2C(C)(C)OC(N[C@@H](CCO)c3ccccc3)=NS2(=O)=O)cc1 -US08937092B2,6,COC(=O)C(C)c1ccc(C#N)c(Cl)c1>>CC(C(=O)O)c1ccc(C#N)c(Cl)c1 -US06608084B1,3,CC(=O)N1CCc2ccccc21.CCCCC(=O)Cl>>CCCCC(=O)c1ccc2c(c1)CCN2C(C)=O -US04654362,2,CC(=O)OC(C)=O.Nc1ccc2c(c1)CCC(COC1CCCCO1)O2>>CC(=O)Nc1ccc2c(c1)CCC(COC1CCCCO1)O2 -US08148383B2,8,CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(O)C(F)(F)F)CC2)c2ccnn12>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(=O)C(F)(F)F)CC2)c2ccnn12 -US06458781B1,2,CCC(C)[C@H](NC(=O)N1CCCCCC1)C(=O)O.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>CCC(C)[C@H](NC(=O)N1CCCCCC1)C(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US20150141433A1,2,Cc1ncc(CNC(=O)c2cnc(CN)cn2)s1.O=S(=O)(Cl)c1cc(F)cc(F)c1>>Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3cc(F)cc(F)c3)cn2)s1 -US20150166480A1,2,O=C(O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2F)c(F)c1.OC[C@H]1CCCN1>>O=C(c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2F)c(F)c1)N1CCC[C@@H]1CO -US05314880,4,COc1ccc(N)c(N)c1.O=CO>>COc1ccc2nc[nH]c2c1 -US20080300191A1,7,NC(=O)CCC(C(O)CF)[N+](=O)[O-]>>NC(=O)CCC(N)C(O)CF -US20120052130A1,1,Cc1c(Cl)ncnc1Cl.c1cc2c(nn1)CCN2>>Cc1c(Cl)ncnc1N1CCc2nnccc21 -US20060270741A1,2,Cc1ccc(C(=O)Cl)cc1.N#CN>>Cc1ccc(C(=O)NC#N)cc1 -US08344135B2,1,CC(C)(C)OC(=O)Nc1cc(O)c(Cl)cc1F.O=[N+]([O-])c1ccc(Cl)nc1>>CC(C)(C)OC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])cn2)c(Cl)cc1F -US07566699B2,3,C#Cc1csc2cccc(OC)c12.Cc1ccc(Br)cc1>>COc1cccc2scc(C#Cc3ccc(C)cc3)c12 -US05591762,4,CCCCc1nc2c(C)cc(N(C)S(=O)(=O)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2C#N)cc1.[N-]=[N+]=[N-]>>CCCCc1nc2c(C)cc(N(C)S(=O)(=O)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US20080051416A1,2,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)O)cc1C(=O)Nc1nccs1.Nc1ncns1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)Nc2ncns2)cc1C(=O)Nc1nccs1 -US20090233929A1,3,Brc1ncccn1.CON(C)C(=O)c1cn(-c2cccc(-c3ccccc3Cl)c2)cn1>>O=C(c1cn(-c2cccc(-c3ccccc3Cl)c2)cn1)c1ncccn1 -US06541467B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1ccc(CN)s1>>CC(C)(C)OC(=O)NCc1ccc(C#N)s1 -US20080269210A1,1,Cc1csc2nc(Cl)nc(Cl)c12.OCC1CNCCO1>>Cc1csc2nc(Cl)nc(N3CCOC(CO)C3)c12 -US20100184765A1,1,CN.Nc1ncnn1-c1cc(Cl)ncn1>>CNc1cc(-n2ncnc2N)ncn1 -US08415370B2,9,O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C1(O)c1cc2c(cc1O)CCCO2>>O=C1C(c2cc3c(cc2O)CCCO3)c2ccccc2N1C(c1ccccc1)c1ccccc1 -US20100130446A1,4,CCOC(=O)C(C(=O)OCC)c1ccc(C(=O)CCC(=O)C(CC2CCOCC2)c2ccc(S(=O)(=O)C3CC3)cc2)nc1.[NH4+]>>CCOC(=O)C(C(=O)OCC)c1ccc(-c2ccc(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)nc1 -US20080312234A1,2,C#Cc1cc(CN)cc(F)c1NS(C)(=O)=O.CC(C)(C)c1ccc(C=CC(=O)O)cn1>>C#Cc1cc(CNC(=O)C=Cc2ccc(C(C)(C)C)nc2)cc(F)c1NS(C)(=O)=O -US07368578B2,6,CCOC(=O)c1ccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4/C=C/c4csc(CC)n4)cc3OC)c(C)o2)o1>>CCc1nc(/C=C/c2cn(-c3ccccc3)nc2OCc2ccc(OCc3nc(-c4ccc(C(=O)O)o4)oc3C)c(OC)c2)cs1 -US20130310379A1,1,CC1(C)CC(NC(=O)c2ccc(O)c(Cl)c2)CC(C)(C)N1.Ic1ccccc1>>CC1(C)CC(NC(=O)c2ccc(Oc3ccccc3)c(Cl)c2)CC(C)(C)N1 -US20110301142A1,3,Cc1noc(-c2ccc(Br)cc2)c1NC(=O)CCc1ccccc1.O=C(O)c1cccc(B(O)O)c1>>Cc1noc(-c2ccc(-c3cccc(C(=O)O)c3)cc2)c1NC(=O)CCc1ccccc1 -US06562989B2,3,COc1ccc(Cl)cc1.OB(O)c1ccccc1>>COc1ccc(-c2ccccc2)cc1 -US20090048259A1,1,COC(=O)C1CNCCN1C(=O)OC(C)(C)C.Clc1nnc(Cl)c2ccccc12>>COC(=O)C1CN(c2nnc(Cl)c3ccccc23)CCN1C(=O)OC(C)(C)C -US08980911B2,2,O=C(O)c1c(Cl)cc(CO)cc1Cl.c1cc2[nH]ccc2cn1>>O=C(c1c(Cl)cc(CO)cc1Cl)n1ccc2cnccc21 -US20150274747A1,1,Cc1cnc(Cl)nc1NC1COC2C(O)COC12.Cn1cc(N)cn1>>Cc1cnc(Nc2cnn(C)c2)nc1NC1COC2C(O)COC12 -US20100311966A1,1,C=CCOC1CN(C(=O)OC(C)(C)C)CCC1=O.NCc1ccccc1>>C=CCO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NCc1ccccc1 -US20070088041A1,1,CN1CCNCC1.COc1nnc(Cl)cc1-c1cc2ccc(C=O)cc2n1C(=O)OC(C)(C)C>>COc1nnc(Cl)cc1-c1cc2ccc(CN3CCN(C)CC3)cc2n1C(=O)OC(C)(C)C -US06509476B1,7,CCOC(=O)/C=C/c1cccc(Br)c1>>OC/C=C/c1cccc(Br)c1 -US20020165282A1,6,CCCCCCCNCCc1ccc(CC(C)(C)C(=O)OCC)cc1>>CCCCCCCNCCc1ccc(CC(C)(C)C(=O)O)cc1 -US20100311966A1,2,CCOC(=O)c1sc(-n2cc3c(n2)CCC(N)C3)nc1C.CCc1[nH]c(C(=O)O)nc1Cl>>CCOC(=O)c1sc(-n2cc3c(n2)CCC(NC(=O)c2nc(Cl)c(CC)[nH]2)C3)nc1C -US05180730,6,CCCc1c(CSc2nccc(OCC(=O)OCC)n2)ccc(C(C)=O)c1O>>CCCc1c(CSc2nccc(OCC(=O)O)n2)ccc(C(C)=O)c1O -US20140309220A1,9,CCc1ccc(C(=O)N2CCC3(CC2)Oc2ccccc2-n2c(C=O)ccc23)cc1OC.NO>>CCc1ccc(C(=O)N2CCC3(CC2)Oc2ccccc2-n2c(/C=N\O)ccc23)cc1OC -US20100234429A1,2,NCc1cccs1.O=C(O)c1ccc(F)nc1F>>O=C(NCc1cccs1)c1ccc(F)nc1F -US20140171407A1,1,C[Si](C)(C)CCOCn1c2cnc(C#N)cc2c2c(Cl)ccnc21.OC[C@H]1CCCCN1>>C[Si](C)(C)CCOCn1c2cnc(C#N)cc2c2c(OC[C@H]3CCCCN3)ccnc21 -US07141684B2,2,C=CCc1cccc(CC=C)c1O.COC(=O)Cl>>C=CCc1cccc(CC=C)c1OC(=O)OC -US05480858,7,Cc1cc(Br)c(C)c2c1SCCC2=O>>Cc1cc(Br)c(C)c2c1SCCC2O -US08524730B2,1,COC(=O)CBr.Cn1cc(-c2ccc3c(c2)C(=O)CC2(CCN(C(=O)c4cc(O)c5ccn(C6CC6)c5c4)CC2)O3)cn1>>COC(=O)COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4cnn(C)c4)ccc2O3)cc2c1ccn2C1CC1 -US20070082912A1,6,CCOC(=O)c1cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccccc2)cc(C(F)(F)F)c1>>Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1cc(C(=O)O)cc(C(F)(F)F)c1 -US20100041654A1,6,CN(CC1CCOCC1)C(=O)OC(C)(C)C>>CNCC1CCOCC1 -US20090181968A1,2,COC(=O)c1nc(OC)cnc1N.Cc1ccc(C(=O)Cl)c2ccccc12>>COC(=O)c1nc(OC)cnc1NC(=O)c1ccc(C)c2ccccc12 -US20030212111A1,2,CCNc1ccc(C#N)cc1N=C1SC(=C2SC3=C(CCNC3)N2C)C(=O)N1Cc1ccccc1.CN(C)CC(=O)Cl>>CCNc1ccc(C#N)cc1N=C1SC(=C2SC3=C(CCN(C(=O)CN(C)C)C3)N2C)C(=O)N1Cc1ccccc1 -US20120201749A1,2,COC(=O)c1sccc1N.O=S(=O)(Cl)c1cc(Br)cc2c1OCC2>>COC(=O)c1sccc1NS(=O)(=O)c1cc(Br)cc2c1OCC2 -US20120264735A1,3,CON(C)C(=O)c1nn(-c2ccc(Cl)cc2)ccc1=O.[Mg+]c1ccc(OC2CCCCO2)cc1>>O=C(c1ccc(OC2CCCCO2)cc1)c1nn(-c2ccc(Cl)cc2)ccc1=O -US20130210811A1,2,CC(C)(C)N.O=S(=O)(Cl)c1ccc(Br)cc1>>CC(C)(C)NS(=O)(=O)c1ccc(Br)cc1 -US08173650B2,6,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(=O)OC(C)(C)C)C(C)(C)C3)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCNC(C)(C)C3)n(C)c2n1 -US20060135771A1,1,CCOC(=O)CBr.C[C@H](NC(=O)c1c(CN2CCNCC2=O)c(-c2cccs2)nc2ccccc12)C1CCCCC1>>CCOC(=O)CN1CCN(Cc2c(-c3cccs3)nc3ccccc3c2C(=O)N[C@@H](C)C2CCCCC2)C(=O)C1 -US20050288346A1,6,COc1ccc(C(C)=O)c(Cl)c1Cl>>CC(=O)c1ccc(O)c(Cl)c1Cl -US20080280879A1,9,COc1ccc2nccc([C@@H](O)CC[C@@H]3CCN(C4CC(c5ccccc5)C4)C[C@@H]3C(N)=O)c2c1>>COc1ccc2nccc([C@@H](O)CC[C@@H]3CCN(C4CC(c5ccccc5)C4)C[C@@H]3C#N)c2c1 -US08013004B2,6,CC(=O)Nc1nc(-c2cccc(Br)c2)c[nH]1>>Nc1nc(-c2cccc(Br)c2)c[nH]1 -US20070054900A1,7,CC(C)(C)C(=O)OCc1nc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cs1>>CC(C)(C)c1cc(-c2csc(CO)n2)cc(C(C)(C)C)c1O -US20150266867A1,2,CC(C)(C)OC(=O)N=C(NCc1cnn(C[C@H]2NC(=O)[C@H]2N)n1)N(CC1CN(C(=O)OC(C)(C)C)C1)C(=O)OC(C)(C)C.CC(C)(C)OC(=O)Nc1nc(/C(=N/OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)C(=O)O)cs1>>CC(C)(C)OC(=O)N=C(NCc1cnn(C[C@H]2NC(=O)[C@H]2NC(=O)/C(=N\OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)c2csc(NC(=O)OC(C)(C)C)n2)n1)N(CC1CN(C(=O)OC(C)(C)C)C1)C(=O)OC(C)(C)C -US08202881B2,1,COc1ccc(CN)c(OC)c1.Cn1cnc2c(Cl)nc(Cl)cc21>>COc1ccc(CNc2nc(Cl)cc3c2ncn3C)c(OC)c1 -US05807875,6,CC(C)(C)OC(=O)N[C@H](CCCNC(N)=N[N+](=O)[O-])C(=O)NCc1cccs1>>NC(=N[N+](=O)[O-])NCCC[C@@H](N)C(=O)NCc1cccs1 -US20050065191A1,2,CCNC1=CC(=O)CC1.COC(=O)Cl>>CCN(C(=O)OC)C1=CC(=O)CC1 -US07754886B2,1,C1COCCN1.Cc1c(Br)sc2ccc(Cl)cc12>>Cc1c(N2CCOCC2)sc2ccc(Cl)cc12 -US20120015957A1,1,C/C(N)=N/OC(=O)c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)c(F)c1>>Cc1noc(-c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)c(F)c2)n1 -US20100152169A1,2,COCCN1CCN(c2ccc3ncn(-c4cc(C(=O)O)ccc4C)c(=O)c3c2)CC1.Nc1ccon1>>COCCN1CCN(c2ccc3ncn(-c4cc(C(=O)Nc5ccon5)ccc4C)c(=O)c3c2)CC1 -US20150284394A1,2,NCc1ccc(Br)cc1F.O=C(O)c1cc2n(n1)CCCC2>>O=C(NCc1ccc(Br)cc1F)c1cc2n(n1)CCCC2 -US20140296515A1,1,CCCN.N#Cc1c(Cl)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1ccc(OCCO)cc1>>CCCNc1nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c(-c2ccc(OCCO)cc2)c1C#N -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.N#Cc1ccccc1O>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4ccccc4C#N)ncnc32)CC1 -US05618941,6,CCOC(=O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cc2ccc(F)cc2)c1>>O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cc2ccc(F)cc2)c1 -US20090036422A1,1,CCC(O)CN.Cc1ccc(CCN(C(=O)C(OS(C)(=O)=O)c2ccccc2)c2ccc(C)c(C)c2)cc1>>CCC(O)CNC(C(=O)N(CCc1ccc(C)cc1)c1ccc(C)c(C)c1)c1ccccc1 -US20130281443A1,1,C1COCCN1.CNC(=O)c1cc(F)ccc1[N+](=O)[O-]>>CNC(=O)c1cc(N2CCOCC2)ccc1[N+](=O)[O-] -US06897231B2,2,COCC(=O)Cl.Nc1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1>>COCC(=O)Nc1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1 -US06420566B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)CNc1ccc(O)cc1>>CC(C)(C)OC(=O)N(CC(=O)O)c1ccc(O)cc1 -US06489322B1,1,CC(C)N(CCO)Cc1cc([N+](=O)[O-])ccc1F>>CC(C)N1CCOc2ccc([N+](=O)[O-])cc2C1 -US20100029628A1,2,CNOC.COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(=O)O)C[C@@H]3c3ccc(OC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(=O)N(C)OC)C[C@@H]3c3ccc(OC)cc3)cc21 -US20150051410A1,7,O=C1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2/C=C/[C@H](COc2cccc(C(F)(F)F)c2)OC2CCCCO2)O1>>OC1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2/C=C/[C@H](COc2cccc(C(F)(F)F)c2)OC2CCCCO2)O1 -US06586475B1,2,CN(C)CCN.O=C(O)c1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1>>CN(C)CCNC(=O)c1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1 -US20150232480A1,7,COC(=O)[C@@H](OC(C)(C)C)c1c(C)c(C)c2nc3cn2c1N1CCC(C)(CC1)OCC=CC[C@H](C)Oc1c(F)cc(F)cc1-c1cccc-3c1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)c(C)c2nc3cn2c1N1CCC(C)(CC1)OCCCC[C@H](C)Oc1c(F)cc(F)cc1-c1cccc-3c1 -US20140350020A1,1,Fc1ccc(CBr)c(F)c1.Ic1n[nH]c2ncccc12>>Fc1ccc(Cn2nc(I)c3cccnc32)c(F)c1 -US04766115,1,N#CBr.c1ccc2c(c1)CNCc1ccccc1-2>>N#CN1Cc2ccccc2-c2ccccc2C1 -US20090226398A1,1,Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F.O=[N+]([O-])c1cc(Br)ccc1CBr>>O=[N+]([O-])c1cc(Br)ccc1Cn1cc2nc(-c3cccc(F)c3F)nc-2cn1 -US06962935B2,4,CCOC(=O)C(Br)C(=O)c1cccc(C#N)c1.NC(=S)c1cccnc1>>CCOC(=O)c1sc(-c2cccnc2)nc1-c1cccc(C#N)c1 -US07244730B2,7,COc1c([N+](=O)[O-])cc(C(C)=O)cc1C(C)(C)C>>COc1c(N)cc(C(C)=O)cc1C(C)(C)C -US20080119442A1,6,COC(=O)c1ccc2ccc(S(=O)(=O)N(Cc3ccccc3)Cc3ccccc3)cc2c1>>O=C(O)c1ccc2ccc(S(=O)(=O)N(Cc3ccccc3)Cc3ccccc3)cc2c1 -US20070219210A1,2,CC(C)(C)N.Cc1ccc(-c2cc(C(=O)O)nn2-c2cnccn2)nc1>>Cc1ccc(-c2cc(C(=O)NC(C)(C)C)nn2-c2cnccn2)nc1 -US04363909,7,CCOC(=O)Cc1cc2c([N+](=O)[O-])cccc2cn1>>CCOC(=O)Cc1cc2c(N)cccc2cn1 -US20130030012A1,1,CN1CCCn2c1cc(Cl)nc2=O.OCc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1>>CN1CCCn2c1cc(OCc1ccc(Oc3ccc(Cl)c(Cl)c3)cc1)nc2=O -US08455521B2,6,CC(F)(F)CCC[C@@](O)(c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>CC(F)(F)CCC[C@@](O)(c1cccc(Cl)c1)[C@@H]1CCCNC1 -US04621901,7,C=CCCC[C@@H]1CC[C@@H](c2ccc(C(C)=O)cc2)CC1>>C=CCCC[C@@H]1CC[C@@H](c2ccc(CC)cc2)CC1 -US06140342,2,CCOC(=O)N(Cc1ccccc1)[C@@H]1C[C@H](C)N(C(=O)Cl)c2cc(OC)c(OC)cc21.OCC(F)(F)F>>CCOC(=O)N(Cc1ccccc1)[C@@H]1C[C@H](C)N(C(=O)OCC(F)(F)F)c2cc(OC)c(OC)cc21 -US06340759B1,6,CCN1CCN(c2nc(-c3ccc(OC[C@@H](C)O[Si](C)(C)C(C)(C)C)cc3)cc3ccccc23)CC1>>CCN1CCN(c2nc(-c3ccc(OCC(C)O)cc3)cc3ccccc23)CC1 -US20090156642A1,6,CN(Cc1cc(S(=O)(=O)c2ccc(Cl)nc2)n(-c2ccccc2F)n1)C(=O)OC(C)(C)C>>CNCc1cc(S(=O)(=O)c2ccc(Cl)nc2)n(-c2ccccc2F)n1 -US20110166020A1,7,CC(C)(C)C(=O)C(CCCn1ccc2cccc(Cl)c21)n1cncn1>>CC(C)(C)C(O)C(CCCn1ccc2cccc(Cl)c21)n1cncn1 -US08318790B2,8,OCc1cc(Br)c(OCc2ccccc2)cc1OCc1ccccc1>>O=Cc1cc(Br)c(OCc2ccccc2)cc1OCc1ccccc1 -US07893099B2,1,C1NCC12COC2.N#CC1(NC(=O)C2CCC(S(=O)(=O)c3ccc(F)cc3Cl)C2)CC1>>N#CC1(NC(=O)[C@@H]2CC[C@@H](S(=O)(=O)c3ccc(N4CC5(COC5)C4)cc3Cl)C2)CC1 -US04371468,1,C=CCBr.Cc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1F)NC2>>C=CCN1Cc2cnc(C)n2-c2ccc(Cl)cc2C1c1ccccc1F -US20150152058A1,3,CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1Br.OB(O)c1ccccc1C(F)(F)F>>CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1-c1ccccc1C(F)(F)F -US20090215778A1,7,CC(=O)c1ccc(C#N)s1>>C[C@@H](O)c1ccc(C#N)s1 -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)cc3F)c2cc1OC.O=C(N=C=S)c1ccc([N+](=O)[O-])cc1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccc([N+](=O)[O-])cc4)cc3F)c2cc1OC -US05854274,2,CC(=O)OC(C)=O.COc1ccc(S(=O)(=O)Nc2cccc3c2Nc2ccccc2CN3)cc1>>COc1ccc(S(=O)(=O)Nc2cccc3c2Nc2ccccc2CN3C(C)=O)cc1 -US20080207708A1,2,COC(=O)c1ccc(C(=O)Cl)cc1.Nc1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1>>COC(=O)c1ccc(C(=O)Nc2csc(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1 -US20070129410A1,6,CCC12CCC(C)(O)CC1CCc1cc(C(=O)OC)ccc12>>CCC12CCC(C)(O)CC1CCc1cc(C(=O)O)ccc12 -US20050113436A1,1,CCOC(=O)c1cc2cc(Br)ccc2[nH]1.Cc1ccc(CBr)cc1>>CCOC(=O)c1cc2cc(Br)ccc2n1Cc1ccc(C)cc1 -US20060167087A1,1,CCOC(=O)Nc1ccc(C=O)cc1.Nc1ccc(Cl)cc1>>CCOC(=O)Nc1ccc(CNc2ccc(Cl)cc2)cc1 -US04221788,7,Clc1ccc(CC2=NCCCCC2)cc1>>Clc1ccc(CC2CCCCCN2)cc1 -US20060287309A1,1,Cc1nc(OCCCC=O)nc2c1ccc(=O)n2C.Fc1ccc2cccc(N3CCNCC3)c2c1>>Cc1nc(OCCCCN2CCN(c3cccc4ccc(F)cc34)CC2)nc2c1ccc(=O)n2C -US06376523B1,3,Cc1cc(NS(=O)(=O)c2ccc(Br)cc2)on1.Cc1cccc(B(O)O)c1>>Cc1cccc(-c2ccc(S(=O)(=O)Nc3cc(C)no3)cc2)c1 -US07435744B2,2,Nc1ccc2oc(=O)[nH]c2c1.O=C(O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc2oc(=O)[nH]c2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1 -US07423030B2,3,COc1ccc(Br)c(C(=O)O)c1.COc1ccc(C(=O)N(C)OC)c(OC)c1>>COc1ccc(C(=O)c2ccc(OC)cc2C(=O)O)c(OC)c1 -US07560571B2,7,COC(=O)c1[nH]ccc1-c1ccc([N+](=O)[O-])cc1>>COC(=O)c1[nH]ccc1-c1ccc(N)cc1 -US20070270476A1,6,COC(=O)c1ccc(C2OCCCO2)cc1F>>O=C(O)c1ccc(C2OCCCO2)cc1F -US20100324092A1,3,Nc1cc(Br)cnc1[N+](=O)[O-].OB(O)c1ccccc1>>Nc1cc(-c2ccccc2)cnc1[N+](=O)[O-] -US20120289494A1,3,O=C1Cc2ccc(Cl)cc2N1.O=Cc1cccc(Cl)c1F>>O=C1Nc2cc(Cl)ccc2/C1=C\c1cccc(Cl)c1F -US20150210641A1,1,CC(=O)N1CCNCC1.COc1cc(F)ccc1-c1ccc(C(OS(C)(=O)=O)c2ccncc2)cc1>>COc1cc(F)ccc1-c1ccc(C(c2ccncc2)N2CCN(C(C)=O)CC2)cc1 -US20080090854A1,1,CC(C)(C)OC(=O)N1CCC(CO)CC1.CCOC(=O)C(C)(CC)NC(=O)c1cc(Cl)c2ccccc2c1O>>CCOC(=O)C(C)(CC)NC(=O)c1cc(Cl)c2ccccc2c1OCC1CCN(C(=O)OC(C)(C)C)CC1 -US20100093705A1,1,CCn1ccc2c(C=O)cccc21.CN>>CCn1ccc2c(CNC)cccc21 -US07932281B2,1,CCCN(CCC)CCCCN(CC)Cc1ccc(CN)cc1.O=Cc1ncc[nH]1>>CCCN(CCC)CCCCN(CC)Cc1ccc(CNCc2ncc[nH]2)cc1 -US05872118,3,CCOC(=O)CBr.O=C1CCc2c(F)cc(F)cc21>>CCOC(=O)CC1(O)CCc2c(F)cc(F)cc21 -US20070072847A1,6,CCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(C)c(O)c(CC)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1>>CCc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(C3CCN(CC(=O)O)CC3)CC2)cc(C)c1O -US20040167155A1,6,COc1ccc(S(=O)(=O)N2c3ccccc3-c3ccccc3[C@@H]2C)cc1>>C[C@H]1c2ccccc2-c2ccccc2N1S(=O)(=O)c1ccc(O)cc1 -US08598345B2,1,Fc1cncc(Br)c1.Oc1cccnc1>>Brc1cncc(Oc2cccnc2)c1 -US20040267014A1,9,Nc1cc(Oc2ncccn2)c(Cl)cc1F.S=C(Cl)Cl>>Fc1cc(Cl)c(Oc2ncccn2)cc1N=C=S -US20090082329A1,2,CC1(C)C(=O)N(c2ccc(SC(F)(F)F)cc2)C(=O)N1Cc1ccnc(N)n1.O=C(Cl)Oc1ccccc1>>CC1(C)C(=O)N(c2ccc(SC(F)(F)F)cc2)C(=O)N1Cc1ccnc(NC(=O)Oc2ccccc2)n1 -US05240923,2,CC(C)(C)N.O=S(=O)(Cl)c1cccs1>>CC(C)(C)NS(=O)(=O)c1cccs1 -US06265415B1,1,CCc1cccc(C)c1C=O.Cc1cc(N)c2nc(C)c(C)n2c1>>CCc1cccc(C)c1CNc1cc(C)cn2c(C)c(C)nc12 -US20090156678A1,1,Fc1cccc(CCl)c1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCc2cccc(F)c2)cc1 -US04563535,7,O=C1C2=C(CCCC2)C(=O)N1c1cc([N+](=O)[O-])ccc1F>>Nc1ccc(F)c(N2C(=O)C3=C(CCCC3)C2=O)c1 -US08957070B2,7,O=[N+]([O-])c1cccc2cc(-c3ncns3)[nH]c12>>Nc1cccc2cc(-c3ncns3)[nH]c12 -US04785010,4,CC(=O)CCC(=O)CN1C(=O)c2ccccc2C1=O.N#CCN>>Cc1ccc(CN2C(=O)c3ccccc3C2=O)n1CC#N -US06215001B1,6,c1ccc(COc2ccc(OCCNCCCn3ccnc3)cc2)cc1>>Oc1ccc(OCCNCCCn2ccnc2)cc1 -US08629157B2,6,CN(C(=O)OC(C)(C)C)c1ccc(N2C(=O)CC[C@H]2C(=O)Nc2cc(C(C)(C)C)on2)cc1>>CNc1ccc(N2C(=O)CC[C@H]2C(=O)Nc2cc(C(C)(C)C)on2)cc1 -US20150191478A1,2,COc1ncc(-c2cc3cncc(-c4cc(C)c(OC)c(C)c4)c3o2)cc1N.O=S(=O)(Cl)c1ccc(F)cc1F>>COc1ncc(-c2cc3cncc(-c4cc(C)c(OC)c(C)c4)c3o2)cc1NS(=O)(=O)c1ccc(F)cc1F -US20150057265A1,1,C[C@H]1CNC[C@@H](NC(=O)OC(C)(C)C)C1.O=[N+]([O-])c1cnccc1Cl>>C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2ccncc2[N+](=O)[O-])C1 -US20080194617A1,1,Clc1cnc2[nH]ccc2c1.Cn1nc(C2CC2)c(C=O)c1Cl>>Cn1nc(C2CC2)c(C=O)c1-n1ccc2cc(Cl)cnc21 -US05252571,1,CCOC(=O)CC1Sc2ccccc2NC1=O.N#CCBr>>CCOC(=O)CC1Sc2ccccc2N(CC#N)C1=O -US20140088078A1,2,CN(Cc1cc(F)ccc1S(=O)(=O)Cl)C(=O)C(F)(F)F.COC(=O)c1c(N)ccc2c1OCC1CC21>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2CN(C)C(=O)C(F)(F)F)ccc2c1OCC1CC21 -US20150166483A1,3,C#C[Si](C(C)C)(C(C)C)C(C)C.Nc1cc(Br)cc(C(=O)O)c1>>CC(C)[Si](C#Cc1cc(N)cc(C(=O)O)c1)(C(C)C)C(C)C -US20070270421A1,2,Nc1ccc(Oc2ccnc(NC(=O)N3CCC(CN4CCCC4)CC3)c2)cc1.O=C=NC(=O)Cc1ccc(F)cc1>>O=C(Cc1ccc(F)cc1)NC(=O)Nc1ccc(Oc2ccnc(NC(=O)N3CCC(CN4CCCC4)CC3)c2)cc1 -US05385897,8,CC(C)(C)[Si](C)(C)OCCO>>CC(C)(C)[Si](C)(C)OCC=O -US20140329799A1,3,COc1nc(SC)nc(NC2CCCN(C(=O)OC(C)(C)C)C2)c1B1OC(C)(C)C(C)(C)O1.Fc1cnc(Br)nc1>>COc1nc(SC)nc(N[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1-c1ncc(F)cn1 -US20100204196A1,7,COc1cc2c(cc1[N+](=O)[O-])N(C(=O)CN(C)C)CCC2>>COc1cc2c(cc1N)N(C(=O)CN(C)C)CCC2 -US07179823B1,1,CCOC(=O)CCc1c[nH]nc1OCC.Cc1oc(-c2ccccc2)nc1COc1ccc(CCl)cn1>>CCOC(=O)CCc1cn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)nc2)nc1OCC -US07256295B2,7,COc1ccc([N+](=O)[O-])c(N)n1>>COc1ccc(N)c(N)n1 -US20130045951A1,9,CN1CCC(=O)CC1.NO>>CN1CCC(=NO)CC1 -US06737416B2,6,CCOC(=O)C=Cc1ccc([N+](=O)[O-])cc1>>O=C(O)C=Cc1ccc([N+](=O)[O-])cc1 -US20080146612A1,6,CCOC(=O)c1ccccc1-c1ccc(Cl)c(C(=O)NCC2(O)CCCCCC2)c1>>O=C(NCC1(O)CCCCCC1)c1cc(-c2ccccc2C(=O)O)ccc1Cl -US20120077793A1,1,CC(C)OC(=O)N1CCC(CO)CC1.Clc1cc(Br)ccn1>>CC(C)OC(=O)N1CCC(COc2cc(Br)ccn2)CC1 -US06384028B1,6,CC(C)(C)OC(=O)N1CCC(/C=C/C(=O)N2CCC[C@@H](C(=O)NCC(CO)C(=O)O)C2)CC1>>O=C(O)C(CO)CNC(=O)[C@@H]1CCCN(C(=O)/C=C/C2CCNCC2)C1 -US07790770B2,7,CC(C)Oc1cc([C@@](Cc2ccccc2)(NC(=O)C(N)C(O)(C(F)(F)F)C(F)(F)F)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F>>CC(C)Oc1cc([C@@](Cc2ccccc2)(NCC(N)C(O)(C(F)(F)F)C(F)(F)F)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F -US08288419B2,6,COC(=O)c1ncoc1-c1cccc(CO)c1>>O=C(O)c1ncoc1-c1cccc(CO)c1 -US20150191465A1,1,C[C@H](N)c1nc2ccn(C)c2cc1C1CCN(C(=O)OC(C)(C)C)C1.Cc1nc(N)nc(Cl)c1C#N>>Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2[C@@H]2CCN(C(=O)OC(C)(C)C)C2)c1C#N -US20060116383A1,6,CCOC(=O)CC(c1ccccc1)n1cnc2ccc(N)cc21>>Nc1ccc2ncn(C(CC(=O)O)c3ccccc3)c2c1 -US20110312930A1,1,Cc1cc(-c2nc(-c3ccc(S(F)(F)(F)(F)F)cc3)no2)nn1Cc1ccc(Cl)nc1.NCCN1CCCC1>>Cc1cc(-c2nc(-c3ccc(S(F)(F)(F)(F)F)cc3)no2)nn1Cc1ccc(NCCN2CCCC2)nc1 -US20150232420A1,6,C=CC(=O)Nc1ccc(C[C@H](NCOCc2ccccc2)C(=O)OC)cc1>>C=CC(=O)Nc1ccc(C[C@H](NCOCc2ccccc2)C(=O)O)cc1 -US05800733,7,C=CC(=O)OCCCCCCOc1ccc(-c2ccc([C@@H]3CC[C@@H](CCC=O)CC3)cc2)cc1>>C=CC(=O)OCCCCCCOc1ccc(-c2ccc([C@@H]3CC[C@@H](CCCO)CC3)cc2)cc1 -US20100256356A1,6,COc1ccc(Cn2nc(C)c3c(Oc4ccc(N5Cc6ccccc6NC5=O)cc4F)ccnc32)cc1>>Cc1n[nH]c2nccc(Oc3ccc(N4Cc5ccccc5NC4=O)cc3F)c12 -US20060183762A1,6,CC(C)(C)OC(=O)NC1(c2ccccc2)CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)NC1(c2ccccc2)CCNC1 -US05120738,2,CC(=O)OCC(C)(C)C(OC(C)=O)C(=O)NCCC(=O)Nc1ccc(O)cc1.CCCCCCCC/C=C\CCCCCCCC(=O)Cl>>CCCCCCCC/C=C\CCCCCCCC(=O)Oc1ccc(NC(=O)CCNC(=O)C(OC(C)=O)C(C)(C)COC(C)=O)cc1 -US20090105327A1,7,O=C1c2ccccc2COc2cc(Nc3ccc(F)cc3[N+](=O)[O-])ccc21>>Nc1cc(F)ccc1Nc1ccc2c(c1)OCc1ccccc1C2=O -US20150126498A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1nc(Br)ccc1N>>COc1nc(Br)ccc1NC(=O)OC(C)(C)C -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)Cl.COCCN1CCNCC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCOC)CC1 -US20110009261A1,2,N#Cc1c(F)cccc1S(=O)(=O)Cl.O=C1CCNC1>>N#Cc1c(F)cccc1S(=O)(=O)N1CCC(=O)C1 -US07435815B2,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Nc1ccc2cn[nH]c2c1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3cn[nH]c3c2)cc1 -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.O=C(N=C=S)c1ccccc1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccccc4)c(C)c3C)c2cc1OC -US06110937,6,Cc1cc(O[Si](C)(C)C(C)(C)C)cc(C)c1OCC1CCCN(C)C1>>Cc1cc(O)cc(C)c1OCC1CCCN(C)C1 -US20130261133A1,2,C=C[C@@H](C#CC#C[C@H](N)CCCCCCCCC)OC(C)=O.O=C(OC(=O)c1ccccc1)c1ccccc1>>C=C[C@@H](C#CC#C[C@@H](CCCCCCCCC)NC(=O)c1ccccc1)OC(C)=O -US20030028022A1,7,COC(=O)c1ccc(-c2nc3ccccc3[nH]2)cc1>>OCc1ccc(-c2nc3ccccc3[nH]2)cc1 -US20110060146A1,7,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(C#CC2(O)CCCCC2)c(C)c1>>CCC(CC)(c1ccc(O)c(C)c1)c1ccc(/C=C/C2(O)CCCCC2)c(C)c1 -US20060264486A1,7,C=CCc1cc(C#N)ccc1O>>CCCc1cc(C#N)ccc1O -US20130253002A1,2,CNCCN(C)C.Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(C(=O)Cl)cc3C)cc12>>Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(C(=O)N(C)CCN(C)C)cc3C)cc12 -US04279887,2,NC1CCCCC1.O=C(Cl)c1ccccc1I>>O=C(NC1CCCCC1)c1ccccc1I -US07662824B2,2,NCCCO.O=C(O)c1cc(Br)c2cc[nH]c2c1>>O=C(NCCCO)c1cc(Br)c2cc[nH]c2c1 -US04199597,7,Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1OCC(=O)NCc1ccccc1>>Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1OCCNCc1ccccc1 -US20060211697A1,1,COc1cc(Br)ccc1O.O=Cc1ccccc1F>>COc1cc(Br)ccc1Oc1ccccc1C=O -US08003785B2,2,CN1CCNCC1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)N2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20100056515A1,1,CCOc1ccc(C(CC)CC)c2c1nc(Cl)n2C.Cc1cc(Cl)cc(Cl)c1O>>CCOc1ccc(C(CC)CC)c2c1nc(Oc1c(C)cc(Cl)cc1Cl)n2C -US20100016401A1,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CN)c1.Cc1nc(CC(=O)O)c(C)s1>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)Cc2nc(C)sc2C)c1 -US20110082164A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1Cc1nnc(Cc2ccccc2)o1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Cc4nnc(Cc5ccccc5)o4)cc3)cc2)CC1 -US20100130737A1,6,CC(C)(C)OC(=O)NC(Cc1ccc(OCc2ccccc2)cc1)c1nnnn1CCC#N>>N#CCCn1nnnc1C(N)Cc1ccc(OCc2ccccc2)cc1 -US20110201604A1,7,CNc1cc(F)c(C(=O)OC)cc1[N+](=O)[O-]>>CNc1cc(F)c(C(=O)OC)cc1N -US06689772B1,1,CN1CCNCC1.O=Cc1cc(Br)cs1>>CN1CCN(Cc2cc(Br)cs2)CC1 -US20090143439A1,3,CC(C)(C)NS(=O)(=O)c1ccc(Br)s1.N#CCc1ccc(B(O)O)cc1>>CC(C)(C)NS(=O)(=O)c1ccc(-c2ccc(CC#N)cc2)s1 -US03950380,7,O=C(O)c1cc(OCc2ccsc2)c(-c2ccccc2)c([N+](=O)[O-])c1>>Nc1cc(C(=O)O)cc(OCc2ccsc2)c1-c1ccccc1 -US20150191476A1,6,c1cc(C2OCCO2)cc(N2CCCC2)c1>>O=Cc1cccc(N2CCCC2)c1 -US08946235B2,1,CN(C)C1CNC1.COc1cc(F)c([N+](=O)[O-])cc1Nc1nccc(-c2c[nH]c3ccccc23)n1>>COc1cc(N2CC(N(C)C)C2)c([N+](=O)[O-])cc1Nc1nccc(-c2c[nH]c3ccccc23)n1 -US05872118,6,CCOC(=O)CC1(O)CCc2c(F)cc(F)cc21>>O=C(O)CC1(O)CCc2c(F)cc(F)cc21 -US08952058B2,1,COc1cc2ncn(Cc3ccc4nc(Br)sc4c3)c2cc1OC.N[C@@H]1CCCC[C@H]1O>>COc1cc2ncn(Cc3ccc4nc(N[C@@H]5CCCC[C@H]5O)sc4c3)c2cc1OC -US20120208819A1,3,C[C@H](NC(=O)c1cccnc1NCCOc1ccc2c(c1)NC(=O)C2)c1ccc(F)c(F)c1.O=Cc1cnc[nH]1>>C[C@H](NC(=O)c1cccnc1NCCOc1ccc2c(c1)NC(=O)/C2=C\c1cnc[nH]1)c1ccc(F)c(F)c1 -US20060160885A1,6,C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](NC(=O)OCc2ccccc2)C1=O>>C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](N)C1=O -US07091222B2,3,C[Si](C)(C)C#Cc1ccnc(Cl)c1.Cc1nc(I)cn1CC(F)F>>Cc1nc(C#Cc2ccnc(Cl)c2)cn1CC(F)F -US20140275179A1,6,CCOC(=O)CCc1ccc(OCc2c(-c3ccc(F)cc3)csc2C(F)(F)F)c(C)c1C>>Cc1c(CCC(=O)O)ccc(OCc2c(-c3ccc(F)cc3)csc2C(F)(F)F)c1C -US09073922B2,6,CC(C)(C)OC(=O)N1CCC(c2cc3c(-c4cc(NCc5cccc(F)c5)ncc4Cl)ccnc3[nH]2)CC1>>Fc1cccc(CNc2cc(-c3ccnc4[nH]c(C5CCNCC5)cc34)c(Cl)cn2)c1 -US20120165309A1,2,CCC(=O)O.N[C@@H]1CC[C@@H](Nc2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1>>CCC(=O)N[C@@H]1CC[C@@H](Nc2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 -US20140194408A1,7,C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CCCC6)C4)c3C=O)cn(C)c2=O)nc1>>C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CCCC6)C4)c3CO)cn(C)c2=O)nc1 -US20030229079A1,1,BrC(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ncc[nH]1>>O=Cc1nccn1C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20100144733A1,2,CNCc1cccc(C(F)(F)F)c1.O=C(O)c1ncn(-c2cc(Cl)c(O)c(Cl)c2)n1>>CN(Cc1cccc(C(F)(F)F)c1)C(=O)c1ncn(-c2cc(Cl)c(O)c(Cl)c2)n1 -US20050159466A1,1,COC(=O)C(=Cc1ccc(O)cc1)C(=O)OC.Cc1oc(-c2ccccc2)nc1CCOS(C)(=O)=O>>COC(=O)C(=Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)OC -US08278457B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(C#N)c1>>COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C#N)c1 -US20140275071A1,1,Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c1nc(S)n2Cc1ccc(Cl)cc1.FC(F)(F)Oc1cccc(CBr)c1>>Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c1nc(SCc1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1 -US20110201629A1,1,CI.O=C1NCCc2c(O)cccc21>>COc1cccc2c1CCNC2=O -US07247628B2,1,C1COCCN1.O=C(CBr)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1>>O=C(CN1CCOCC1)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1 -US20020040016A1,6,c1ccc(C(c2ccccc2)N2CC(Oc3cccc4c3CCC4)C2)cc1>>c1cc2c(c(OC3CNC3)c1)CCC2 -US09024017B2,1,Brc1nccs1.CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CNC[C@@]2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1>>CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CN(c3nccs3)C[C@@]2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 -US04743685,2,NN1CCNC1=O.O=C(O)c1cc(=O)c(OCc2ccccc2)c[nH]1>>O=C(NN1CCNC1=O)c1cc(=O)c(OCc2ccccc2)c[nH]1 -US20050203087A1,1,C=CCOC(=O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br.OC1CCCCC1>>C=CCOC(=O)COc1c(C(=O)OC2CCCCC2)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br -US20120178732A1,2,C1COCCN1.O=S(=O)(Cl)c1cc(F)c(Br)cc1F>>O=S(=O)(c1cc(F)c(Br)cc1F)N1CCOCC1 -US07713994B2,7,O=C(O)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>Nc1ccc(N2CCC(C(=O)O)CC2)cc1 -US04350822,6,CCCCCCCCCCCCCOc1ccc(CNc2ccc(C(=O)OCC)cc2)cc1>>CCCCCCCCCCCCCOc1ccc(CNc2ccc(C(=O)O)cc2)cc1 -US20130217702A1,2,Cc1nc(-c2cc3cc(F)ccc3n2-c2ccc(CNC(=O)C3(N)CC3)cc2)no1.O=C(O)c1cncc(C(F)(F)F)c1>>Cc1nc(-c2cc3cc(F)ccc3n2-c2ccc(CNC(=O)C3(NC(=O)c4cncc(C(F)(F)F)c4)CC3)cc2)no1 -US07235581B2,6,CC(C)(C)OC(=O)N[C@H]1CCN(c2ccc(OCc3ccccc3)cc2)C1=O>>CC(C)(C)OC(=O)N[C@H]1CCN(c2ccc(O)cc2)C1=O -US04988699,7,Nc1nc2c(s1)CC(C(=O)N1CCN(c3ccccn3)CC1)CC2>>Nc1nc2c(s1)CC(CN1CCN(c3ccccn3)CC1)CC2 -US20090247517A1,9,CC(C)c1ccc(-c2nc3c(-c4ccccc4)nn(CC(=O)O)c3c(=O)n2-c2ccc(Cl)cc2)cc1.N>>CC(C)c1ccc(-c2nc3c(-c4ccccc4)nn(CC(N)=O)c3c(=O)n2-c2ccc(Cl)cc2)cc1 -US04469698,2,CC(=O)O.CCCCn1c(N)c(N)c(=O)[nH]c1=O>>CCCCn1c(N)c(NC(C)=O)c(=O)[nH]c1=O -US07091222B2,1,CC(C)CBr.Cc1cc(C#Cc2c[nH]c(C)n2)ccn1>>Cc1cc(C#Cc2cn(CC(C)C)c(C)n2)ccn1 -US08822471B2,2,Cc1cnc(N2CCC(NC3CC3)CC2)cn1.O=C(O)c1ccc(-c2cnco2)c(F)c1>>Cc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)c(F)c3)C3CC3)CC2)cn1 -US07902203B2,6,CC(C)(C)OC(=O)COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3ccccc3n(NCC3CC3)c1=O)N2>>O=C(O)COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3ccccc3n(NCC3CC3)c1=O)N2 -US20130196971A1,2,Brc1ccc(-c2cnnn2C[C@@H]2CCNC2)cc1.O=C(Cl)C1CC1>>O=C(C1CC1)N1CC[C@@H](Cn2nncc2-c2ccc(Br)cc2)C1 -US20100069629A1,1,COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4)cn2)cc1.O=C(c1ccc(Br)cn1)N1CCN(CCO)CC1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccc(C(=O)N4CCN(CCO)CC4)nc3)cn2)cc1 -US20150191472A1,2,CC(C)(C)OC(=O)N1[C@@H](CO)[C@H]2OC(C)(C)O[C@H]2[C@@H]1c1c[nH]c2c(N=[N+]=[N-])ncnc12.CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC[C@@H]1[C@H]2OC(C)(C)O[C@H]2[C@H](c2c[nH]c3c(N=[N+]=[N-])ncnc23)N1C(=O)OC(C)(C)C -US20050209274A1,2,Nc1ccc(CN2CCC(NC(=O)c3cc(=O)c4ccc(F)cc4o3)CC2)cc1F.O=C(O)CCN1CCCCC1>>O=C(CCN1CCCCC1)Nc1ccc(CN2CCC(NC(=O)c3cc(=O)c4ccc(F)cc4o3)CC2)cc1F -US20110269734A1,2,CS(=O)(=O)Cl.C[C@H](CCO)C1CCN(C(=O)OC(C)(C)C)CC1>>C[C@H](CCOS(C)(=O)=O)C1CCN(C(=O)OC(C)(C)C)CC1 -US06310070B1,1,Cc1cc(CO)cc(C)c1OCc1ccccc1.NC(=O)c1[nH]cnc1N=Cc1ccccc1>>Cc1cc(Cn2cnc(N=Cc3ccccc3)c2C(N)=O)cc(C)c1OCc1ccccc1 -US20090264445A1,10,CCOC(=O)/C=C(\C)Oc1ccc(Cl)cc1Cl.O=C1CCC(=O)N1Br>>CCOC(=O)/C=C(\CBr)Oc1ccc(Cl)cc1Cl -US20140303156A1,2,CN(C)c1cccc(N)c1.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>CN(C)c1cccc(NC(=O)Cc2nc(N3CCOCC3)cc(=O)[nH]2)c1 -US20050020605A1,2,CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.O=C(O)c1cnnc2ccccc12>>CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3cnnc4ccccc34)CC2)CC1 -US20130150394A1,3,CON1CCC(=O)CC1.NC1CC1.[C-]#N>>CON1CCC(C#N)(NC2CC2)CC1 -US20110251173A1,9,C[C@@H]1CN(c2ccc(OCc3ccccc3)cc2)C(=O)c2c(Cl)ncnc2O1.N>>C[C@@H]1CN(c2ccc(OCc3ccccc3)cc2)C(=O)c2c(N)ncnc2O1 -US20120322788A1,1,CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c2[nH]c(=O)ccc12.Cc1nc(C(=O)N2CCOC3(CCN(CCCOc4cccc(C=O)c4)CC3)C2)cs1>>Cc1nc(C(=O)N2CCOC3(CCN(CCCOc4cccc(CNC[C@H](O[Si](C)(C)C(C)(C)C)c5ccc(O)c6[nH]c(=O)ccc56)c4)CC3)C2)cs1 -US08324252B2,1,Cc1cc(N)n[nH]1.N#Cc1cc(F)c(F)nc1F>>Cc1cc(Nc2nc(F)c(C#N)cc2F)n[nH]1 -US08791102B2,6,O=C(Cn1cncn1)N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1>>NCCC[C@H](NC(=O)Cn1cncn1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1 -US20090099044A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOCCSC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1ccc(S(=O)(=O)OCCOCCSC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20020025968A1,6,COc1ccc2nc(-n3ccnc3)nc(NCc3ccccc3)c2c1>>Oc1ccc2nc(-n3ccnc3)nc(NCc3ccccc3)c2c1 -US20100087424A1,1,CS(=O)(=O)OCC1CCc2c(F)cnc3ccc(=O)n1c23.O=C(NC[C@H]1CNC[C@H]1O)OCc1ccccc1>>O=C(NC[C@H]1CN(CC2CCc3c(F)cnc4ccc(=O)n2c34)C[C@H]1O)OCc1ccccc1 -US07572809B2,1,Clc1nc(Nc2cc[nH]n2)cc2ccccc12.Oc1ccccc1>>c1ccc(Oc2nc(Nc3cc[nH]n3)cc3ccccc23)cc1 -US20150252044A1,2,COCCNCc1ccccc1.COc1ccc(-c2cncc3ccc(C(=O)O)nc23)cc1>>COCCN(Cc1ccccc1)C(=O)c1ccc2cncc(-c3ccc(OC)cc3)c2n1 -US06995179B2,6,COC(OC)C1=C(C(=O)OCC=Cc2ccccc2)C(c2cccc(Cl)c2)C(C(=O)OCCC#N)=C(C)N1>>CC1=C(C(=O)OCCC#N)C(c2cccc(Cl)c2)C(C(=O)OCC=Cc2ccccc2)=C(C=O)N1 -US20110201599A1,2,Nc1nccc(-c2ccccc2)c1[N+](=O)[O-].O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C(Nc1nccc(-c2ccccc2)c1[N+](=O)[O-])c1ccc([N+](=O)[O-])cc1 -US05093332,2,COCCNCCOCCOC.NS(=O)(=O)c1cc2c(s1)S(=O)(=O)C(CC(=O)O)C(=O)N2>>COCCOCCN(CCOC)C(=O)CC1C(=O)Nc2cc(S(N)(=O)=O)sc2S1(=O)=O -US05843975,2,CCOC(=O)Cl.Cn1nc(N)c2ccc(OCc3ccccc3)cc21>>CCOC(=O)Nc1nn(C)c2cc(OCc3ccccc3)ccc12 -US20090076004A1,1,CCOC(=O)Cc1c(C(=O)OCC)c2cc(O)ccc2n1-c1ccc(OC(F)(F)F)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)Cc1c(C(=O)OCC)c2cc(Oc3ccc(C(F)(F)F)cc3)ccc2n1-c1ccc(OC(F)(F)F)cc1 -US20030028022A1,2,CCO.Nc1ccc(C(=O)O)cn1>>CCOC(=O)c1ccc(N)nc1 -US07071198B1,1,CC(C)=O.FC(F)(F)c1ccc(-c2n[nH]c(C3CCNCC3)c2-c2ccncc2)cc1>>CC(C)N1CCC(c2[nH]nc(-c3ccc(C(F)(F)F)cc3)c2-c2ccncc2)CC1 -US20150158878A1,6,CCOC(=O)c1csc(Nc2nc(C)cc(C(F)(F)F)n2)n1>>Cc1cc(C(F)(F)F)nc(Nc2nc(C(=O)O)cs2)n1 -US20150112071A1,6,COC(=O)c1cc(-c2cnn(C)c2)cc(C(F)(F)F)c1>>Cn1cc(-c2cc(C(=O)O)cc(C(F)(F)F)c2)cn1 -US20060122239A1,6,CC(C)CN(c1ccc(C(O)(C#CC(=O)OC(C)(C)C)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1>>CC(C)CN(c1ccc(C(O)(C#CC(=O)O)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1 -US20080292548A1,1,CNC.COC(=O)c1ccc(F)c(F)c1>>COC(=O)c1ccc(N(C)C)c(F)c1 -US20150183763A1,3,C[C@@H](OCc1cc(F)cc(B2OC(C)(C)C(C)(C)O2)c1)C(F)(F)F.Nc1cc(I)n(-c2ccccc2)n1>>C[C@@H](OCc1cc(F)cc(-c2cc(N)nn2-c2ccccc2)c1)C(F)(F)F -US20150236271A1,3,Brc1cccc2ccsc12.O=[N+]([O-])c1ccccc1B(O)O>>O=[N+]([O-])c1ccccc1-c1cccc2ccsc12 -US20130190290A1,2,Cc1ccc(N)cc1-n1ccn2nc(-c3cccnc3)cc12.O=C(O)c1cccc(C(F)(F)F)c1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 -US04755212,1,O=[N+]([O-])c1c(F)cccc1F.Oc1ccc(C(F)(F)F)cc1Cl>>O=[N+]([O-])c1c(F)cccc1Oc1ccc(C(F)(F)F)cc1Cl -US08415383B2,6,COc1ccc(F)c(C#N)c1F>>N#Cc1c(F)ccc(O)c1F -US20120289500A1,2,Nn1nc(-c2ccnc(Cl)c2)c2ccccc2c1=O.O=C(O)CC1(O)CCCCC1>>O=C(CC1(O)CCCCC1)Nn1nc(-c2ccnc(Cl)c2)c2ccccc2c1=O -US04113464,1,BrCC1OCCO1.CCCN>>CCCNCC1OCCO1 -US08536214B2,2,CS(=O)(=O)Cl.N[C@H]1Cc2ccc(Cn3cc(CO)c(C(F)(F)F)n3)cc2C1>>CS(=O)(=O)N[C@H]1Cc2ccc(Cn3cc(CO)c(C(F)(F)F)n3)cc2C1 -US20090023704A1,1,CCCn1c(=O)[nH]c(=O)c2c1nc(CC)n2C.Clc1ccc(CBr)cc1>>CCCn1c(=O)n(Cc2ccc(Cl)cc2)c(=O)c2c1nc(CC)n2C -US20080269170A1,2,COCCNC1CCS(=O)(=O)C1.O=S(=O)(Cl)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1>>COCCN(C1CCS(=O)(=O)C1)S(=O)(=O)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1 -US20020107422A1,1,CC(=CCBr)CBr.O=S([O-])c1ccccc1>>CC(=CCS(=O)(=O)c1ccccc1)CBr -US09050345B2,2,CC(=O)Cl.NC1(c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)CC1>>CC(=O)NC1(c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)CC1 -US06150352,2,COC(CNc1cnccn1)OC.Cc1cc(C)cc(-c2c(OCCC3CCCCN3C(=O)OCC[Si](C)(C)C)c3cc(N=C=O)c(Cl)cc3[nH]c2=O)c1>>COC(CN(C(=O)Nc1cc2c(OCCC3CCCCN3C(=O)OCC[Si](C)(C)C)c(-c3cc(C)cc(C)c3)c(=O)[nH]c2cc1Cl)c1cnccn1)OC -US20150094302A1,2,CCOC(=O)c1cc2c(n1CCN)CC(F)(F)CC2>>O=C1NCCn2c1cc1c2CC(F)(F)CC1 -US08669255B2,6,CC(C)(C)OC(=O)NC(C(=O)N1CCN2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2C1)c1cccc(C(F)(F)F)c1>>NC(C(=O)N1CCN2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2C1)c1cccc(C(F)(F)F)c1 -US04588732,9,Cc1nc(CCl)ccc1OCc1ccccc1.[N-]=[N+]=[N-]>>Cc1nc(CN=[N+]=[N-])ccc1OCc1ccccc1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCCCN(C)S(C)(=O)=O.Oc1ccc2[nH]ccc2c1>>COc1cc2c(Oc3ccc4[nH]ccc4c3)ncnc2cc1OCCCN(C)S(C)(=O)=O -US05495023,2,C/C=C(/C=C/CO)CC.CCN=C=O>>C/C=C(/C=C/COC(=O)NCC)CC -US20100227862A1,2,Fc1ccc(C2CNCC23CCN(Cc2ccccc2)CC3)cc1.O=C(Cl)c1ccnc(Cl)c1>>O=C(c1ccnc(Cl)c1)N1CC(c2ccc(F)cc2)C2(CCN(Cc3ccccc3)CC2)C1 -US06727264B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.COc1ccc(Oc2cccc(C=O)c2)cc1>>COc1ccc(Oc2cccc(CN3CCC(c4cccc(NC(=O)C(C)C)c4)CC3)c2)cc1 -US20090029994A1,1,FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1.Fc1ccc(C(F)(F)F)cc1CNc1ncc(Br)cn1>>Fc1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(Br)cn1 -US06150415,2,CCCCCCCCN=C=O.CCCCCN>>CCCCCCCCNC(=O)NCCCCC -US05565479,4,CC1CC(Br)C(=O)c2ccccc21.NC(=S)Cc1c[nH]cn1>>CC1Cc2sc(Cc3c[nH]cn3)nc2-c2ccccc21 -US20090163495A1,2,NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1.O=C(O)Cc1csc(-c2cnccn2)n1>>O=C(Cc1csc(-c2cnccn2)n1)NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1 -US08614209B2,3,O=C(O)c1csc(Br)c1.OB(O)c1ccccc1>>O=C(O)c1csc(-c2ccccc2)c1 -US20030114467A1,6,CC(=O)OCCCCN1N=C(c2ccc(C)cc2)C2C(N)=NC=NC21>>Cc1ccc(C2=NN(CCCCO)C3N=CN=C(N)C23)cc1 -US20140371199A1,3,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Br)cc2N2CCN(C(=O)OC(C)(C)C)CC2)CC1.CC1(C)OB(c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4c3)cc2N2CCN(C(=O)OC(C)(C)C)CC2)CC1 -US20070078135A1,1,CC(C)(C)OC(=O)NC1CCNCC1.FC(F)(F)c1ccc(-c2nnc(Cl)cc2-c2ccncc2Cl)cc1>>CC(C)(C)OC(=O)NC1CCN(c2cc(-c3ccncc3Cl)c(-c3ccc(C(F)(F)F)cc3)nn2)CC1 -US20040235822A1,6,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([C@H](O)c4cccc[n+]4[O-])cc2)CCN3C(=O)C(F)(F)F)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([C@H](O)c4cccc[n+]4[O-])cc2)CCN3)cc1 -US20130261077A1,2,CC(=O)NN.Cc1cc(C(=O)O)ccc1Br>>CC(=O)NNC(=O)c1ccc(Br)c(C)c1 -US05252601,2,CC(=O)SCC1(C(=O)O)CCc2ccccc2C1.NCC(O)C(=O)OCc1ccccc1>>CC(=O)SCC1(C(=O)NCC(O)C(=O)OCc2ccccc2)CCc2ccccc2C1 -US20100298287A1,1,COC(=O)c1ccc(Cl)c2nc(Nc3ccc(C(N)=O)cc3C)n(CCCO)c12>>COC(=O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(C(N)=O)cc1C -US20070254901A1,3,CCSc1ncc2cc(-c3ccccc3)c(Cl)nc2n1.O=Cc1ccc(B(O)O)cc1>>CCSc1ncc2cc(-c3ccccc3)c(-c3ccc(C=O)cc3)nc2n1 -US09073947B2,2,Nc1cccc(-c2c(N)ncnc2Oc2ccc(Oc3ccccc3)cc2)c1.O=C(O)/C=C/CN1CCCC(F)(F)C1>>Nc1ncnc(Oc2ccc(Oc3ccccc3)cc2)c1-c1cccc(NC(=O)/C=C/CN2CCCC(F)(F)C2)c1 -US04444584,1,CCOC(=O)C(C)Oc1ccc(O)cc1.O=[N+]([O-])c1cc2cc(Cl)ccc2nc1Cl>>CCOC(=O)C(C)Oc1ccc(Oc2nc3ccc(Cl)cc3cc2[N+](=O)[O-])cc1 -US20130324528A1,6,CC(=O)N(C(C)=O)c1c(Br)ccnc1C>>CC(=O)Nc1c(Br)ccnc1C -US20100113539A1,7,O=C(NC/C=C/c1cccc([N+](=O)[O-])c1)C(F)(F)F>>Nc1cccc(/C=C/CNC(=O)C(F)(F)F)c1 -US08178533B2,7,O=Cc1c(C2CC2)nc2ccc(Cl)nn12>>OCc1c(C2CC2)nc2ccc(Cl)nn12 -US20080312322A1,7,O=C(O)/C=C/c1ccccc1Cc1cc(Cl)ccc1OCC(=O)O>>O=C(O)CCc1ccccc1Cc1cc(Cl)ccc1OCC(=O)O -US20090029963A1,6,C[C@H]1C[C@H](N2CCCC2)CCN1C(=O)OC(C)(C)C>>C[C@H]1C[C@H](N2CCCC2)CCN1 -US20150148340A1,6,CCOC(=O)c1cn(-c2ccc3c(c2)oc(=O)n3C)c(=O)n(C2CCCc3c2cccc3C(F)(F)F)c1=O>>Cn1c(=O)oc2cc(-n3cc(C(=O)O)c(=O)n(C4CCCc5c4cccc5C(F)(F)F)c3=O)ccc21 -US06660742B2,7,CC(=O)OCCc1c([N+](=O)[O-])cc(NC(=O)OC(C)(C)C)c2ccccc12>>CC(=O)OCCc1c(N)cc(NC(=O)OC(C)(C)C)c2ccccc12 -US06143764,2,COc1cc(OC)c(N=C=O)cc1Cl.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC>>COc1cc(OC)c(NC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1Cl -US07435744B2,2,Cc1ccc(CC2CCN(C(=O)C(=O)O)CC2)cc1.Nc1ccc2c(c1)CS(=O)(=O)N2>>Cc1ccc(CC2CCN(C(=O)C(=O)Nc3ccc4c(c3)CS(=O)(=O)N4)CC2)cc1 -US20110301145A1,6,CC(C)(C)OC(=O)N1CCCC(Nc2cc(-c3ccc(F)c(NC(=O)c4cnc(C(C)(C)C)cn4)c3)n[nH]c2=O)C1>>CC(C)(C)c1cnc(C(=O)Nc2cc(-c3cc(NC4CCCNC4)c(=O)[nH]n3)ccc2F)cn1 -US20140094462A1,1,C=CCN.O=Cc1ccc(Cl)cc1>>C=CCNCc1ccc(Cl)cc1 -US20120208819A1,1,CN.Clc1ncc2cc(Br)ccc2n1>>CNc1ncc2cc(Br)ccc2n1 -US05559113,2,NCc1c[nH]cn1.O=C(O)CCCCc1ccccc1>>O=C(CCCCc1ccccc1)NCc1c[nH]cn1 -US05089642,1,CCOC(=O)CBr.N[C@@H](c1ccccc1)[C@H](O)c1ccccc1>>CCOC(=O)CN[C@@H](c1ccccc1)[C@H](O)c1ccccc1 -US20100158863A1,7,Cc1nc(C(=O)N2CCN(C)CC2)nn1-c1ccc([N+](=O)[O-])cc1>>Cc1nc(C(=O)N2CCN(C)CC2)nn1-c1ccc(N)cc1 -US20050250784A1,2,COC(=O)c1cnc(N2CCNCC2)s1.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>COC(=O)c1cnc(N2CCN(S(=O)(=O)c3ccc(-c4ccccc4)cc3)CC2)s1 -US08026374B2,6,C=C(C)C(=O)OC>>C=C(C)C(=O)O -US20150239900A1,8,CC(C)(C)OC(=O)N1CCN(c2nc(CO)nc3c(F)c(Br)c(Cl)cc23)CC1>>CC(C)(C)OC(=O)N1CCN(c2nc(C=O)nc3c(F)c(Br)c(Cl)cc23)CC1 -US06818644B1,1,COc1cccc(N2CC(C)NC(C)C2)n1.O=C(NCC(F)(F)F)C1(CCCCBr)c2ccccc2-c2ccccc21>>COc1cccc(N2CC(C)N(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4-c4ccccc43)C(C)C2)n1 -US20040209886A1,1,Cc1c(N)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12.OB(O)c1ccccc1>>Cc1c(Nc2ccccc2)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12 -US08314138B2,1,CNCCc1ccccn1.Cc1nc(-c2cncc(I)n2)sc1C(=O)NCc1ccc(F)cc1>>Cc1nc(-c2cncc(N(C)CCc3ccccn3)n2)sc1C(=O)NCc1ccc(F)cc1 -US04079135,1,CCOC(=O)CCl.O=[N+]([O-])c1cccc(Cl)c1O>>CCOC(=O)COc1c(Cl)cccc1[N+](=O)[O-] -US04125732,1,COC(=O)C(Br)c1ccc(OCCOc2ccc(Cl)cc2)cc1.Oc1ccc(Cl)cc1>>COC(=O)C(Oc1ccc(Cl)cc1)c1ccc(OCCOc2ccc(Cl)cc2)cc1 -US08461134B2,5,Nc1cc([N+](=O)[O-])ccc1Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1cc([N+](=O)[O-])ccc1Cl)C(F)(F)F -US08921389B2,2,COC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2-c2ccccc2)c1O.NCCC(=O)O>>O=C(O)CCNC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2-c2ccccc2)c1O -US20050240023A1,6,CC(C)C[C@@H](CO[Si](C)(C)C(C)(C)C)N[C@@H](c1ccc(Br)cc1)C(F)F>>CC(C)C[C@@H](CO)N[C@@H](c1ccc(Br)cc1)C(F)F -US08524917B2,8,CC(C)Oc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)O)n(Cc3ccccn3)c2c1>>CC(=O)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OC(C)C)cc2n1Cc1ccccn1 -US07148226B2,7,CC1(C)OC(=O)C=C(CC(O)(C#Cc2ccc(C(C)(C)C#N)c(F)c2)C2CCCC2)O1>>CC1(C)OC(=O)C=C(CC(O)(CCc2ccc(C(C)(C)C#N)c(F)c2)C2CCCC2)O1 -US04499091,6,CCOC(=O)c1cn(N)c2cc(Cl)c(F)cc2c1=O>>Nn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21 -US06967197B2,2,CC(C)N=C=O.O=C(CC1(c2ccc(-c3ccc(-c4cnco4)cc3)s2)CCNCCS1(=O)=O)NOC1CCCCO1>>CC(C)NC(=O)N1CCC(CC(=O)NOC2CCCCO2)(c2ccc(-c3ccc(-c4cnco4)cc3)s2)S(=O)(=O)CC1 -US20110118241A1,1,CCCC[Sn](CCCC)(CCCC)[Sn](CCCC)(CCCC)CCCC.O=C1CCc2cc(Br)cc3c2N1CC3>>CCCC[Sn](CCCC)(CCCC)c1cc2c3c(c1)CCN3C(=O)CC2 -US20100317679A1,1,CCOC(=O)C1CCNCC1.ClCc1ccccc1>>CCOC(=O)C1CCN(Cc2ccccc2)CC1 -US20130204009A1,1,COC(=O)c1cccc(OCc2nc3ccc(Oc4ncc(Br)c(Cl)c4Br)cc3n2C)c1.C[O-]>>COC(=O)c1cccc(OCc2nc3ccc(Oc4ncc(Br)c(OC)c4Br)cc3n2C)c1 -US05977101,6,COC(=O)CC1Nc2ccc(C(=O)NCc3ncc[nH]3)cc2CN(CCc2ccccc2)C1=O>>O=C(O)CC1Nc2ccc(C(=O)NCc3ncc[nH]3)cc2CN(CCc2ccccc2)C1=O -US20130143892A1,2,O=C(O)c1cnc(-n2ccnc2)nc1.c1ccc(-c2noc(N3CCC(NC4CC4)CC3)n2)cc1>>O=C(c1cnc(-n2ccnc2)nc1)N(C1CC1)C1CCN(c2nc(-c3ccccc3)no2)CC1 -US20080194670A1,7,O=C(O)CCc1ccc(CO)cc1>>OCCCc1ccc(CO)cc1 -US20150126763A1,5,CC(C)=CCCC(C)=CCCC(C)=CC=O.SCCCS>>CC(C)=CCCC(C)=CCCC(C)=CC1SCCCS1 -US04701447,8,CCCSc1ccc([N+](=O)[O-])c(N)c1.O=C(OO)c1cccc(Cl)c1>>CCCS(=O)c1ccc([N+](=O)[O-])c(N)c1 -US20120149737A1,7,CCOc1c(C(F)(F)F)cc([N+](=O)[O-])cc1C(F)(F)F>>CCOc1c(C(F)(F)F)cc(N)cc1C(F)(F)F -US20130158022A1,9,N.O=C(O)/C=C/c1cccs1>>NC(=O)/C=C/c1cccs1 -US05591762,6,CCCc1nc2c(C)cc(-c3cn(CC4CC4)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCc1nc2c(C)cc(-c3cn(CC4CC4)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US07576098B2,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.c1ccc(-c2c[nH]cn2)cc1>>c1ccc(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1 -US20110071194A1,2,COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)N)c1.NC(=O)NCC(=O)O>>COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)NC(=O)CNC(N)=O)c1 -US20050222410A1,6,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2ccoc2)nc1>>Nc1ccccc1NC(=O)c1ccc(-c2ccoc2)nc1 -US20130190330A1,1,COC(=O)c1ccc(Br)cc1CBr.O=c1[nH]nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F>>COC(=O)c1ccc(Br)cc1Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O -US20140155419A1,1,COC(=O)Cc1ccc(O)cc1.Cc1ncccc1C(=O)CBr>>COC(=O)Cc1ccc(OCC(=O)c2cccnc2C)cc1 -US09096600B2,10,COc1c(C(C)=O)cc(Cl)c(C)c1Br.O=C1CCC(=O)N1Br>>COc1c(C(C)=O)cc(Cl)c(CBr)c1Br -US20140356322A1,2,CCOc1cccc(C(=O)N2C[C@H](O)C[C@H]2C(=O)O)c1.NCc1ccc(-c2ccccc2)cc1>>CCOc1cccc(C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3ccccc3)cc2)c1 -US04235923,9,CCCCCCC1OC1(C(=O)OCC)C(=O)OCC.N>>CCCCCCC1OC1(C(N)=O)C(=O)OCC -US04985569,7,O=[N+]([O-])CC12CCCN1CCC2>>NCC12CCCN1CCC2 -US20060058328A1,6,c1ccc(CN2CCCC23CCN(c2cccnc2)C3)cc1>>c1cncc(N2CCC3(CCCN3)C2)c1 -US08080566B1,2,CC(C)(C)OC(=O)N1CCCC(O)C1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CC(C)(C)OC(=O)N1CCCC(OS(=O)(=O)c2ccc([N+](=O)[O-])cc2)C1 -US07230017B2,2,C1CCNC1.O=C([O-])CC(=O)Nc1cccc(C(F)(F)F)c1>>O=C(CC(=O)N1CCCC1)Nc1cccc(C(F)(F)F)c1 -US20110028467A1,2,COc1c(Br)cc(C(=O)Cl)cc1Br.O=C1COc2ccncc2N1>>COc1c(Br)cc(C(=O)N2C(=O)COc3ccncc32)cc1Br -US07816395B2,2,CCNC[C@H](CC(=O)OC(C)(C)C)Nc1ccc(C#N)c(Cl)c1>>CCN1C[C@@H](Nc2ccc(C#N)c(Cl)c2)CC1=O -US20120309738A1,2,Cn1c(Nc2cc(CN)c(F)cc2Cl)nc2cc(Cl)c(N3CCC(C(F)(F)F)CC3)cc21.O=C(O)C1(C(F)(F)F)CC1>>Cn1c(Nc2cc(CNC(=O)C3(C(F)(F)F)CC3)c(F)cc2Cl)nc2cc(Cl)c(N3CCC(C(F)(F)F)CC3)cc21 -US20150196545A1,7,COc1cc2nccc(Oc3ccc([N+](=O)[O-])cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC -US20120122942A1,6,COC(=O)C[C@H](C)CC(=O)OCC[Si](C)(C)C>>C[C@@H](CC(=O)O)CC(=O)OCC[Si](C)(C)C -US08173813B2,7,CN(C)CCN1C(=O)CCc2ccccc21>>CN(C)CCN1CCCc2ccccc21 -US20100130738A1,6,COc1ccc(C2=NNC(=O)C2(C)C)cc1F>>CC1(C)C(=O)NN=C1c1ccc(O)c(F)c1 -US05607960,7,CN1CCC[C@@H]1Cc1c[nH]c2ccc(C=CC(C)(O)C(F)(F)F)cc12>>CN1CCC[C@@H]1Cc1c[nH]c2ccc(CCC(C)(O)C(F)(F)F)cc12 -US06555552B2,7,CC(C)(C)OC(=O)[C@@H]1C[C@@]2(c3ccccc3)[C@@H](NCc3ccccc3)[C@@H](F)C[C@@H]1N2Cc1ccccc1>>OC[C@@H]1C[C@@]2(c3ccccc3)[C@@H](NCc3ccccc3)[C@@H](F)C[C@@H]1N2Cc1ccccc1 -US20090111794A1,1,Clc1nc2ccccc2s1.O=C(O)c1ccc(O)cc1F>>O=C(O)c1ccc(Oc2nc3ccccc3s2)cc1F -US20040014968A1,2,COC(=O)C(CC1CCCC1)c1ccc(Cl)cc1.Nc1nccs1>>O=C(Nc1nccs1)C(CC1CCCC1)c1ccc(Cl)cc1 -US08263594B2,7,CC(C)CNc1c([N+](=O)[O-])c2nnnn2c2ccc(OCc3ccccc3)cc12>>CC(C)CNc1c(N)c2nnnn2c2ccc(OCc3ccccc3)cc12 -US20140303139A1,3,CC1(C)OB(c2ccc(Oc3ccc(F)cc3)cc2)OC1(C)C.C[C@H](Nc1cc(C(=O)OC(C)(C)C)nc(Cl)n1)C(N)=O>>C[C@H](Nc1cc(C(=O)OC(C)(C)C)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1)C(N)=O -US09156840B2,1,ClCCCBr.O=C1COc2ccccc2N1>>O=C1COc2ccccc2N1CCCCl -US06608049B2,7,CCCCCc1nn(C(=O)OC(C)(C)C)c2ccc(Oc3c(C)cc([N+](=O)[O-])cc3C)cc12>>CCCCCc1nn(C(=O)OC(C)(C)C)c2ccc(Oc3c(C)cc(N)cc3C)cc12 -US20080261921A1,3,CN(C)C(=O)C(C#N)c1cc(Cl)ncn1.COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(B3OC(C)(C)C(C)(C)O3)cc12>>COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(-c3cc(C(C#N)C(=O)N(C)C)ncn3)cc12 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1cccc(Oc2ccccc2)c1>>FC(F)(F)c1cccc2c(-c3cccc(NCc4cccc(Oc5ccccc5)c4)c3)c(Cc3ccccc3)cnc12 -US20110269712A1,1,CCOC(=O)CBr.Clc1cc(Cl)[nH]n1>>CCOC(=O)Cn1nc(Cl)cc1Cl -US20060142364A1,2,FC(F)(F)CNCC(F)(F)F.O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>O=C(c1ccc(F)c([N+](=O)[O-])c1)N(CC(F)(F)F)CC(F)(F)F -US06414179B1,1,C=C(C)C.O=C(O)c1ccc(CBr)cc1>>CC(C)(C)OC(=O)c1ccc(CBr)cc1 -US20150183801A1,1,CN(C)C1CNC1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(-c2cncc(F)c2)c1>>CN(C)C1CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncc(F)c2)C1 -US20080051418A1,7,CCOC(=O)CCc1cc(OC(C)C)nn1Cc1ccccc1OC>>COc1ccccc1Cn1nc(OC(C)C)cc1CCCO -US05420132,2,Nc1ccccc1.O=C(O)C1=COc2cc(O)ccc2O1>>O=C(Nc1ccccc1)C1=COc2cc(O)ccc2O1 -US20030153596A1,3,CC(C)(C)c1ccc(C=O)cc1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=Cc1ccc(C(C)(C)C)cc1 -US20120035122A1,6,CC(C)(C)OC(=O)N1CC(F)(c2ccc(C3=NOC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)cc2)C1>>FC1(c2ccc(C3=NOC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)cc2)CNC1 -US08470828B2,2,N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1.O=C(O)C(O)C(F)(F)F>>O=C(N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1)C(O)C(F)(F)F -US20080261941A1,6,CCOc1ccc(Oc2cccc(C=C3CCN(C(=O)OC(C)(C)C)CC3)c2)nc1>>CCOc1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1 -US20030073836A1,2,Cc1ccc(-c2ccc(CN)cc2)cc1.Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O>>Cc1ccc(-c2ccc(CNC(=O)c3cc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)cn3C)cc2)cc1 -US20120283264A1,1,CCOP(OCC)OCC.Fc1ccc(F)c(CBr)c1>>CCOP(=O)(Cc1cc(F)ccc1F)OCC -US08501780B2,8,CCS(=O)(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(-c4cccc(CO)c4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(-c4cccc(C=O)c4)cc23)CC1 -US20100029653A1,1,Fc1ccccc1Cc1n[nH]c2ccccc12.Nc1nc(N)nc(Cl)n1>>Nc1nc(N)nc(-n2nc(Cc3ccccc3F)c3ccccc32)n1 -US08211923B2,2,CNC.O=C(O)c1cc2cc(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)ccc2[nH]1>>CN(C)C(=O)c1cc2cc(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)ccc2[nH]1 -US20130116234A1,6,CCOC(=O)c1c(N2CCCC2=O)nc2ccc(Cl)cc2c1-c1ccccc1>>O=C(O)c1c(N2CCCC2=O)nc2ccc(Cl)cc2c1-c1ccccc1 -US20060205980A1,6,COc1cc(F)c(C(C)(C)C(F)(F)F)c(F)c1>>CC(C)(c1c(F)cc(O)cc1F)C(F)(F)F -US20120015942A1,1,COC(=O)C1(C)CCc2ccc(O)cc2C1.OB(O)c1ccc(Cl)cc1>>COC(=O)C1(C)CCc2ccc(Oc3ccc(Cl)cc3)cc2C1 -US20090264405A1,1,CC1CN(c2ccc(C(F)(F)F)cn2)C(C)CN1.O=C(CBr)Nc1ccc(Br)nc1>>CC1CN(c2ccc(C(F)(F)F)cn2)C(C)CN1CC(=O)Nc1ccc(Br)nc1 -US07531545B2,6,NC1=Nc2cnc(Oc3ccccc3)cc2CN1[C@@H](CCC(=O)N(CCOCc1ccccc1)C1CCC(C(=O)OCc2ccccc2)CC1)C1CCOCC1>>NC1=Nc2cnc(Oc3ccccc3)cc2CN1[C@@H](CCC(=O)N(CCOCc1ccccc1)[C@@H]1CC[C@H](C(=O)O)CC1)C1CCOCC1 -US04407930,7,Cc1nc2c(O)cc([N+](=O)[O-])cc2o1>>Cc1nc2c(O)cc(N)cc2o1 -US20140213549A9,6,CCOC(=O)CCCCOc1cnc(N2CCC(c3nc4c(c(C5CCC(F)(F)CC5)c3C(F)c3ccc(C(F)(F)F)cc3)C(O)CC(C)(C)C4)CC2)nc1>>CC1(C)Cc2nc(C3CCN(c4ncc(OCCCCC(=O)O)cn4)CC3)c(C(F)c3ccc(C(F)(F)F)cc3)c(C3CCC(F)(F)CC3)c2C(O)C1 -US05614633,7,O=[N+]([O-])c1ccc2c(c1)C(c1ccccn1)=CC(CF)(CF)O2>>Nc1ccc2c(c1)C(c1ccccn1)=CC(CF)(CF)O2 -US07517873B2,7,COC(=O)C[C@H]1CCCN1c1nc(Cl)ncc1[N+](=O)[O-]>>COC(=O)C[C@H]1CCCN1c1nc(Cl)ncc1N -US06630600B1,6,CCOC(=O)[C@H](Cc1ccc(OCCc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1)OCC>>CCO[C@@H](Cc1ccc(OCCc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1)C(=O)O -US20110092461A1,1,CC1CNCC(C)O1.O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(Cl)nc1>>CC1CN(c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cn2)CC(C)O1 -US05057506,2,CCOC(=O)CCNCC(=O)OCC.CCOC(=O)Cl>>CCOC(=O)CCN(CC(=O)OCC)C(=O)OCC -US07947685B2,2,COC(=O)c1nccnc1Br.Cc1cc(N)ccn1>>Cc1cc(NC(=O)c2nccnc2Br)ccn1 -US20120095039A1,3,C#CCCCc1ccccc1.O=S(=O)(c1ccccc1)n1cc(I)c(-c2cccnc2)n1>>O=S(=O)(c1ccccc1)n1cc(C#CCCCc2ccccc2)c(-c2cccnc2)n1 -US20030191171A1,4,CC(=O)CC(=O)CC(=O)OC(C)C.CNN>>Cc1cc(CC(=O)OC(C)C)n(C)n1 -US07671073B2,3,Brc1ccc2ncnn2c1.CN(C)C(=O)[C@@H](C1CC=C(B2OC(C)(C)C(C)(C)O2)CC1)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(F)(F)C1>>CN(C)C(=O)[C@@H](C1CC=C(c2ccc3ncnn3c2)CC1)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(F)(F)C1 -US20110021523A1,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(F)c(F)c1C(=O)c1ccncc1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(F)c(F)c2C(=O)c2ccncc2)cc1 -US20100048568A1,3,CC(=O)Cl.c1cc2cc[nH]c2cn1>>CC(=O)c1c[nH]c2cnccc12 -US05958918,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc[nH]n1>>Cc1ccn(C(=O)OC(C)(C)C)n1 -US20040058978A1,6,CC(C)(C)OC(=O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1>>O=C(O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1 -US20150094295A1,1,CC(C)(Br)C=O.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(C(C)(C)C=O)CC1 -US20140155394A1,1,CCOC(=O)c1nc(Cl)nc(Cl)c1[N+](=O)[O-].Cc1cc(N)n[nH]1>>CCOC(=O)c1nc(Cl)nc(Nc2cc(C)[nH]n2)c1[N+](=O)[O-] -US20100204228A1,2,NCC(F)(F)F.O=S(=O)(Cl)c1ccc(Br)cc1>>O=S(=O)(NCC(F)(F)F)c1ccc(Br)cc1 -US20060079504A1,2,CN1CCC(C2CCNCC2)CC1.O=C(O)C(CC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)Cc1ccc(Cl)c(C(F)(F)F)c1>>CN1CCC(C2CCN(C(=O)C(CC(=O)N3CCC(N4Cc5ccccc5NC4=O)CC3)Cc3ccc(Cl)c(C(F)(F)F)c3)CC2)CC1 -US07288654B2,2,CCCCOCCOc1ccc(-c2cnc3c(c2)C=C(C(=O)O)CCN3CC(C)C)cc1.CN(Cc1ccc(N)cc1)C1CCOCC1>>CCCCOCCOc1ccc(-c2cnc3c(c2)C=C(C(=O)Nc2ccc(CN(C)C4CCOCC4)cc2)CCN3CC(C)C)cc1 -US08232273B2,6,CC(C)(C)OC(=O)Nc1cccc(OCCCc2sc(N3CCc4cccc(C(=O)Nc5nc6ccccc6s5)c4C3)nc2C(=O)O)c1>>Nc1cccc(OCCCc2sc(N3CCc4cccc(C(=O)Nc5nc6ccccc6s5)c4C3)nc2C(=O)O)c1 -US20060084645A1,1,C1COCCN1.Fc1ccc(-c2nc(Cl)cc(Nc3ccc(OC(F)(F)F)cc3)n2)cc1>>Fc1ccc(-c2nc(Nc3ccc(OC(F)(F)F)cc3)cc(N3CCOCC3)n2)cc1 -US08143270B2,7,CC(C)(C)OC(=O)NCCNc1c([N+](=O)[O-])c(Cl)nc2ccccc12>>CC(C)(C)OC(=O)NCCNc1c(N)c(Cl)nc2ccccc12 -US20150239862A1,1,Clc1cccc(Cl)c1CBr.OCCO>>OCCOCc1c(Cl)cccc1Cl -US09073891B2,2,Nc1scc(Br)c1-c1nccs1.O=C(O)CN1C(=O)CCc2ncccc21>>O=C(CN1C(=O)CCc2ncccc21)Nc1scc(Br)c1-c1nccs1 -US04166818,2,CC(=O)OC(C)=O.CCCCCCNc1nc(C)no1>>CCCCCCN(C(C)=O)c1nc(C)no1 -US20080312226A1,2,COc1cccc(N=C=O)c1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>COc1cccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)c1 -US20060084690A1,7,CCOC(=O)c1cnoc1-c1cccc(Cl)c1>>OCc1cnoc1-c1cccc(Cl)c1 -US20080004297A1,1,COc1ccc(N)cc1OC.Cc1nc(Cl)c2cc([N+](=O)[O-])ccc2n1>>COc1ccc(Nc2nc(C)nc3ccc([N+](=O)[O-])cc23)cc1OC -US20040192653A1,7,Cn1ncc2cc(Oc3ncccc3C#N)ccc21>>Cn1ncc2cc(Oc3ncccc3CN)ccc21 -US20050004134A1,4,CC(C)n1nc(C(Br)C(=O)c2ccccc2)ccc1=O.NC(N)=S>>CC(C)n1nc(-c2sc(N)nc2-c2ccccc2)ccc1=O -US20130079373A1,6,CC(C)(C)OC(=O)NCc1ccc(C(F)(F)F)nc1OC1CCOCC1>>NCc1ccc(C(F)(F)F)nc1OC1CCOCC1 -US07074801B1,1,Cc1ccc(CCl)cc1.c1ccc(C(c2ccccc2)(c2ccccc2)n2ccc(-c3ccc4ncnc(N5CCNCC5)c4c3)n2)cc1>>Cc1ccc(CN2CCN(c3ncnc4ccc(-c5ccn(C(c6ccccc6)(c6ccccc6)c6ccccc6)n5)cc34)CC2)cc1 -US04363813,2,CCOC(=O)c1sc(-c2cc(OC)c(OC)c(OC)c2)nc1C.NN>>COc1cc(-c2nc(C)c(C(=O)NN)s2)cc(OC)c1OC -US20020193402A1,1,C=CCN1C2CCC(O)C1(c1ccccc1)CC2C#N.FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1>>C=CCN1[C@H]2CC[C@@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@]1(c1ccccc1)C[C@H]2C#N -US08435980B2,2,NC1CCCC(Nc2cc(I)cc(Cl)n2)C1.O=S(=O)(Cl)C1CC1>>O=S(=O)(NC1CCCC(Nc2cc(I)cc(Cl)n2)C1)C1CC1 -US05594135,2,C=CCOC(=O)Cl.NCc1ccc(C(=O)O)cc1>>C=CCOC(=O)NCc1ccc(C(=O)O)cc1 -US20070161684A1,8,CCC(CC)NC(=O)c1ccc(-c2cc(C(=O)NC3CC3)cc(F)c2C)nc1.O=C(OO)c1cccc(Cl)c1>>CCC(CC)NC(=O)c1ccc(-c2cc(C(=O)NC3CC3)cc(F)c2C)[n+]([O-])c1 -US07067702B2,3,C=C.O=C(CC(=O)C(F)(F)F)c1ccc(Br)s1>>C=Cc1ccc(C(=O)CC(=O)C(F)(F)F)s1 -US04954518,2,CS(=O)(=O)Nc1cc2occ(C(=O)O)c(=O)c2cc1Oc1ccccc1.Nc1nnn[nH]1>>CS(=O)(=O)Nc1cc2occ(C(=O)Nc3nnn[nH]3)c(=O)c2cc1Oc1ccccc1 -US20090247567A1,4,NNC(N)=S.O=C1c2cc(Br)ccc2OCCC1Br>>NNc1nc2c(s1)CCOc1ccc(Br)cc1-2 -US07135487B2,2,CC(C)S(=O)(=O)Cl.NCCc1ccc(Br)cc1>>CC(C)S(=O)(=O)NCCc1ccc(Br)cc1 -US20070249670A1,2,COC(=O)[C@@H](N)[C@@H](C)OC(C)(C)C.COc1ccc(-c2ccc(C(=O)O)c([N+](=O)[O-])c2)cc1F>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)c(F)c2)cc1[N+](=O)[O-])[C@@H](C)OC(C)(C)C -US06451819B2,1,CC(C)(C)OC(=O)N1CCC(S)C1.O=c1oc2cc(Br)ccc2n1C(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC(Sc2ccc3c(c2)oc(=O)n3C(c2ccccc2)(c2ccccc2)c2ccccc2)C1 -US07220744B2,2,CC(C)(C)COc1ccc(S(C)(=O)=O)cc1C(=O)O.CCS(=O)(=O)c1cnc(N2CCNCC2)s1>>CCS(=O)(=O)c1cnc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OCC(C)(C)C)CC2)s1 -US05420273,3,CC(c1ccc2c(c1)C(C)(C)CCN2C)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1>>CC(=Cc1ccccc1)c1ccc2c(c1)C(C)(C)CCN2C -US05821246,1,COc1cc2ncnc(Cl)c2cc1OC(C)=O.Cc1cc(N)ccc1OCc1ccccn1>>COc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(C)c3)c2cc1OC(C)=O -US04478741,2,CCCCCC(=O)Cl.O=C(O)c1ccc(O)cc1>>CCCCCC(=O)Oc1ccc(C(=O)O)cc1 -US20120157434A1,1,O=C(CBr)c1ccc(Br)cn1.c1c[nH]cn1>>O=C(Cn1ccnc1)c1ccc(Br)cn1 -US20110144090A1,6,COC(=O)C(C)c1cn(C)c2c(F)cc(Br)c(OC)c12>>COc1c(Br)cc(F)c2c1c(C(C)C(=O)O)cn2C -US20080249093A1,6,COC(=O)C1Cc2ccc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)c(C)c2C1>>Cc1c(-c2noc(-c3cnc(OC(C)C)c(Cl)c3)n2)ccc2c1CC(C(=O)O)C2 -US20140030221A1,6,COC(=O)C(C)(C)/C=C/c1ccc2cnc(C(C)O[Si](C)(C)C(C)(C)C)nc2c1>>CC(O[Si](C)(C)C(C)(C)C)c1ncc2ccc(/C=C/C(C)(C)C(=O)O)cc2n1 -US20110301353A1,6,CCOC(=O)Cc1[nH]c(C(=O)OC(C)(C)C)c(C)c1C(=O)OCC>>CCOC(=O)c1c(CC(=O)O)[nH]c(C(=O)OC(C)(C)C)c1C -US08993605B2,2,CS(=O)(=O)Cl.O=c1onc(-c2nonc2NCCO)n1-c1ccc(F)c(Br)c1>>CS(=O)(=O)OCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Br)c1 -US05614548,2,CCCCCCCCCCCCCCCCSCC(CO)OC.CS(=O)(=O)Cl>>CCCCCCCCCCCCCCCCSCC(COS(C)(=O)=O)OC -US20090298899A1,2,N#CC=Cc1cccc(N)c1.O=C(O)c1cc(Br)ccc1F>>N#CC=Cc1cccc(NC(=O)c2cc(Br)ccc2F)c1 -US20050119251A1,2,NCCC1CC1.O=C(O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nc1>>O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nc1 -US20020119979A1,2,COc1ccc(S(=O)(=O)Cl)cc1OC.NC(Cc1cccnc1)C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>COc1ccc(S(=O)(=O)NC(Cc2cccnc2)C(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1OC -US07067534B1,3,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.O=[N+]([O-])c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)N1CC=C(c2ccc([N+](=O)[O-])cc2)CC1 -US20100076026A1,2,Clc1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1.O=C(Cl)OC1CCCCC1>>O=C(OC1CCCCC1)N(c1c2ccccc2nn1-c1ccc(Cl)cc1)C1CCCCC1 -US20060264460A1,1,CC=O.N#Cc1cnc2c(Cl)cc(NCc3cn(C4CCNCC4)nn3)cc2c1Nc1ccc(F)c(Cl)c1>>CCN1CCC(n2cc(CNc3cc(Cl)c4ncc(C#N)c(Nc5ccc(F)c(Cl)c5)c4c3)nn2)CC1 -US06432950B1,1,FC(F)(F)c1cc2c(NCc3ccc4c(c3)OCO4)nc(Cl)nc2s1.c1cn[nH]c1>>FC(F)(F)c1cc2c(NCc3ccc4c(c3)OCO4)nc(-n3cccn3)nc2s1 -US20110212918A1,7,N#Cc1ccccc1S(=O)(=O)Nc1cc2c(cc1F)COB2O>>NCc1ccccc1S(=O)(=O)Nc1cc2c(cc1F)COB2O -US07105671B2,2,COC(=O)C(CC1CCCC1O)c1ccc(Cl)c(Cl)c1.Nc1nccs1>>O=C(Nc1nccs1)C(CC1CCCC1O)c1ccc(Cl)c(Cl)c1 -US08410150B2,6,COc1ncc(C#C[Si](C)(C)C)cn1>>C#Cc1cnc(OC)nc1 -US20060014768A1,1,CN.O=c1cc(Cl)n(-c2cccc([N+](=O)[O-])c2)c(=O)n1C1CC1>>CNc1cc(=O)n(C2CC2)c(=O)n1-c1cccc([N+](=O)[O-])c1 -US20100179172A1,1,CC(C)(C)OC(=O)CBr.Nc1cc(C(F)(F)F)c(Br)c(C(F)(F)F)c1>>CC(C)(C)OC(=O)CNc1cc(C(F)(F)F)c(Br)c(C(F)(F)F)c1 -US20040023974A1,6,CCCCCNC(=O)[C@H](Cc1cccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)c1)NC(=O)OC(C)(C)C>>CCCCCNC(=O)[C@@H](N)Cc1cccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)c1 -US20090239845A1,1,CC=O.Cc1cc(NC(=O)c2ccc3c(c2)CCNC3)nn1Cc1cc(Cl)ccc1OCC(C)C>>CCN1CCc2cc(C(=O)Nc3cc(C)n(Cc4cc(Cl)ccc4OCC(C)C)n3)ccc2C1 -US06147097,7,CC(C)c1nc(CCO)n(Cc2ccccc2[N+](=O)[O-])c1Sc1cc(Cl)cc(Cl)c1>>CC(C)c1nc(CCO)n(Cc2ccccc2N)c1Sc1cc(Cl)cc(Cl)c1 -US20100087471A1,1,Cc1ccc(NN=C(c2ccccc2)c2ccccc2)cc1.Fc1ccc(CCBr)cc1>>Cc1ccc(N(CCc2ccc(F)cc2)N=C(c2ccccc2)c2ccccc2)cc1 -US20090062277A1,3,CC(C)(O)C1CCN(c2ncc(B(O)O)cc2C(F)F)CC1.COc1cc2nncc(Br)c2cc1OC>>COc1cc2nncc(-c3cnc(N4CCC(C(C)(C)O)CC4)c(C(F)F)c3)c2cc1OC -US04636560,8,COc1ccc(CSC(CO)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1>>COc1ccc(CSC(C=O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1 -US20090291938A1,2,C=CC[C@H]1CN(C2CCCC2)c2nc(Nc3ccc(C(=O)O)cc3OC)ncc2N(C)C1=O.CN1CC(N)C1>>C=CC[C@H]1CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CN(C)C4)cc3OC)ncc2N(C)C1=O -US05648373,6,CCOC(=O)CCCCCCn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1>>O=C(O)CCCCCCn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1 -US20140336198A1,1,COc1ccc([C@@H](C)N)cc1.O=Cc1ccccn1>>COc1ccc([C@@H](C)NCc2ccccn2)cc1 -US20070219181A1,2,CC(C)(C)OC(=O)NN.O=C(O)C(CCCCl)c1ccc(F)cc1>>CC(C)(C)OC(=O)NNC(=O)C(CCCCl)c1ccc(F)cc1 -US20140038988A1,2,CC(=O)OCC(=O)Cl.CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N)nc2N1c1cccc(C(F)(F)F)c1>>CC(=O)OCC(=O)Nc1nc2n(n1)[C@H](c1ccc(C#N)cc1)C(C#N)=C(C)N2c1cccc(C(F)(F)F)c1 -US06171866B2,7,CCOc1cc([N+](=O)[O-])c(OCC)cc1CCN>>CCOc1cc(CCN)c(OCC)cc1N -US08013156B2,1,Clc1ccncc1.OCc1ccccc1N1CCNCC1>>c1ccc(N2CCNCC2)c(COc2ccncc2)c1 -US05086055,1,CN1CC(CCCl)OC1=O.Clc1ccccc1N1CCNCC1>>CN1CC(CCN2CCN(c3ccccc3Cl)CC2)OC1=O -US20140228361A1,6,C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCN4CC5CN(C(=O)OC(C)(C)C)CC5C4)cc23)c1>>C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCN4CC5CNCC5C4)cc23)c1 -US20130109718A1,8,Cc1ccccc1C(CC1(C2CCC(O)CC2)OCCO1)c1ccc(S(C)(=O)=O)cc1>>Cc1ccccc1C(CC1(C2CCC(=O)CC2)OCCO1)c1ccc(S(C)(=O)=O)cc1 -US05312830,7,O=[N+]([O-])c1ccc(Oc2ccc(I)cc2)cc1>>Nc1ccc(Oc2ccc(I)cc2)cc1 -US07943748B2,1,COC(CBr)OC.COc1ccc(S)cc1>>COc1ccc(SCC(OC)OC)cc1 -US08153652B2,3,C=CC(=O)N(C)Cc1c(C)[nH]c2ccccc12.COCCN1Cc2cc(Br)cnc2NC1=O>>COCCN1Cc2cc(/C=C/C(=O)N(C)Cc3c(C)[nH]c4ccccc34)cnc2NC1=O -US06608070B1,1,CCOC(=O)C=Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(C)cc1.O=C(CBr)c1ccc(Cl)cc1>>CCOC(=O)C=Cc1ccc(Cl)cc1N(CC(=O)c1ccc(Cl)cc1)S(=O)(=O)c1ccc(C)cc1 -US07863444B2,6,COc1cc(-c2cn(C3CCCC3)c3ncnc(Cl)c23)ccc1NC(=O)OC(C)(C)C>>COc1cc(-c2cn(C3CCCC3)c3ncnc(Cl)c23)ccc1N -US07087590B2,5,C[C@]12CC[C@@H]3[C@H]4CCC(O)C[C@H]4CC[C@H]3[C@@H]1CCC2=O.OCCO>>C[C@]12CC[C@@H]3[C@H]4CCC(O)C[C@H]4CC[C@H]3[C@@H]1CCC21OCCO1 -US20090247526A1,1,Cc1csc(N)n1.Clc1cc(Sc2ccccc2Cl)ccn1>>Cc1csc(Nc2cc(Sc3ccccc3Cl)ccn2)n1 -US07696226B2,3,CC(C)(C)OC(=O)N[C@H](C=O)Cc1ccccc1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C -US20060094767A1,2,C[C@](O)(CO)Cn1cc([N+](=O)[O-])nc1Cl.O=C(Cl)N1CCN(c2ccc(OC(F)(F)F)cc2)CC1>>C[C@](O)(COC(=O)N1CCN(c2ccc(OC(F)(F)F)cc2)CC1)Cn1cc([N+](=O)[O-])nc1Cl -US08664216B2,6,c1ccc(CN2CCC3(CC2)OCCc2ccccc23)cc1>>c1ccc2c(c1)CCOC21CCNCC1 -US09150555B2,1,CC1OCCC1=O.Cc1cc(Br)cnc1C1=CCNCC1>>Cc1cc(Br)cnc1C1=CCN([C@H]2CCO[C@H]2C)CC1 -US09150555B2,1,CC1OCCC1=O.Cc1cc(Br)cnc1C1=CCNCC1>>Cc1cc(Br)cnc1C1=CCN([C@@H]2CCO[C@H]2C)CC1 -US20140206681A1,6,CCOc1cc(C(=O)OC)c(F)cc1I>>CCOc1cc(C(=O)O)c(F)cc1I -US20010047094A1,8,Cc1cccc(C)n1.O=C(OO)c1cccc(Cl)c1>>Cc1cccc(C)[n+]1[O-] -US07160901B2,1,CN(C)CCCl.CS(=O)(=O)Nc1cccc([N+](=O)[O-])c1>>CN(C)CCN(c1cccc([N+](=O)[O-])c1)S(C)(=O)=O -US20110262407A1,3,O=C1CN2CCC1CC2.O=Cc1cccnc1>>O=C1C(=Cc2cccnc2)N2CCC1CC2 -US05359055,8,CC[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4=C[C@@H](O)[C@@H]5O[C@@H]5[C@]4(C)[C@H]3CC[C@]12C>>CC[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4=CC(=O)[C@@H]5O[C@@H]5[C@]4(C)[C@H]3CC[C@]12C -US05236797,3,N#CCC#N.O=C1C=C(c2ccccc2)P(=O)(c2ccccc2)C(c2ccccc2)=C1>>N#CC(C#N)=C1C=C(c2ccccc2)P(=O)(c2ccccc2)C(c2ccccc2)=C1 -US08247556B2,7,CN(C)c1nc2cc([N+](=O)[O-])ccc2s1>>CN(C)c1nc2cc(N)ccc2s1 -US20080255152A1,1,COc1cc(C=O)ccc1Oc1ccc(C(N)=O)cn1.Cc1ccc(CCN)cc1>>COc1cc(CNCCc2ccc(C)cc2)ccc1Oc1ccc(C(N)=O)cn1 -US04528298,1,O=[N+]([O-])c1cc(C(F)(F)F)ccc1Cl.Sc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)[nH]1>>O=[N+]([O-])c1cc(C(F)(F)F)ccc1Sc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)[nH]1 -US04315933,5,Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)c1cnc(-c2ccc(NC(=O)C(F)(F)F)cc2)nc1O -US08987307B2,3,CNc1cnc(C)cc1I.COc1cc(F)ccc1B(O)O>>CNc1cnc(C)cc1-c1ccc(F)cc1OC -US20090197866A1,2,CCN(CC)C(=O)Cl.CN(C)CCNc1cc2[nH]c(-c3nn(C4CCCCO4)cc3N)nc2cc1F>>CCN(CC)C(=O)Nc1cn(C2CCCCO2)nc1-c1nc2cc(F)c(NCCN(C)C)cc2[nH]1 -US20150252038A1,6,COC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN(C(c3ccc(F)cc3Cl)C(F)(F)F)C2)cc1F>>O=C(O)c1cc(C2CC2)c(O[C@@H]2CCCN(C(c3ccc(F)cc3Cl)C(F)(F)F)C2)cc1F -US07067537B2,4,CCc1ccncc1C(=O)CBr.NC(=S)c1cccc(S(N)(=O)=O)c1>>CCc1ccncc1-c1csc(-c2cccc(S(N)(=O)=O)c2)n1 -US20120277237A1,3,C#CCCn1cc2c(Cl)cccc2n1.FCc1cccc(Br)n1>>FCc1cccc(C#CCCn2cc3c(Cl)cccc3n2)n1 -US08404673B2,2,COc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)O.N[C@@H]1CCC[C@@H]1N1CCCC1>>COc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)N[C@@H]1CCC[C@@H]1N1CCCC1 -US04818431,7,COc1ccc(C(=O)CC2CCCOC2)cc1>>COc1ccc(CCC2CCCOC2)cc1 -US20040133008A1,2,CC(C)(C)OC(=O)N(CCn1cccn1)c1ccc(N)cn1.CN(C)c1cc(Cl)ccc1C(=O)O>>CN(C)c1cc(Cl)ccc1C(=O)Nc1ccc(N(CCn2cccn2)C(=O)OC(C)(C)C)nc1 -US07635695B2,7,CCOC(=O)c1cnc(N(Cc2ccccc2)Cc2ccccc2)c([N+](=O)[O-])c1N>>CCOC(=O)c1cnc(N(Cc2ccccc2)Cc2ccccc2)c(N)c1N -US04783460,1,COC(=O)COc1ccc(CC(C)=O)cc1.c1ccc(C2CNCCO2)cc1>>COC(=O)COc1ccc(CC(C)N2CCOC(c3ccccc3)C2)cc1 -US07084149B2,3,CC(C)[Mg+].CCOc1ccc2cc(C(=O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2c1>>CCOc1ccc2cc(C(O)(c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)C(C)C)ccc2c1 -US08987256B2,6,CC(=O)OCc1ccc(C(C(=O)Nc2cccc(CCC(=O)OC(C)(C)C)c2C)C2CCCC2)cc1>>Cc1c(CCC(=O)OC(C)(C)C)cccc1NC(=O)C(c1ccc(CO)cc1)C1CCCC1 -US20070287726A1,9,Cc1cccc(C)c1CNc1cc(C(=O)N(C)C)nc2c(CO)c(C)[nH]c12>>Cc1cccc(C)c1CNc1cc(C(=O)N(C)C)nc2c(C)c(C)[nH]c12 -US20020010182A1,7,O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(Cc2ccc([N+](=O)[O-])cc2)C[C@H]1Cc1ccc(Cl)c(Cl)c1>>Nc1ccc(CN2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3ccc(Cl)c(Cl)c3)C2)cc1 -US07977345B2,2,Nc1ccc(Oc2ncnc3[nH]ccc23)c(F)c1.O=C(Cc1ccccc1)N=C=S>>O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2ncnc3[nH]ccc23)c(F)c1 -US20060106012A1,7,O=C1COc2cc(S(=O)(=O)c3ccccc3)ccc2N1>>O=S(=O)(c1ccccc1)c1ccc2c(c1)OCCN2 -US20030055259A1,3,OB(O)c1ccc(F)cc1.OCc1cncc(Br)c1>>OCc1cncc(-c2ccc(F)cc2)c1 -US20090156642A1,1,Cc1ccc(S(=O)[O-])cn1.O=Cc1cc(-c2cccnc2F)c(Br)s1>>Cc1ccc(S(=O)(=O)c2sc(C=O)cc2-c2cccnc2F)cn1 -US04410536,4,Cc1csc2ccc(NN)cc12.O=C1CCNCC1>>Cc1csc2ccc3[nH]c4c(c3c12)CNCC4 -US20150166564A1,2,Cn1cc(-c2cc(N)n(C)n2)cn1.O=C(Cl)Oc1ccccc1>>Cn1cc(-c2cc(NC(=O)Oc3ccccc3)n(C)n2)cn1 -US20050059726A1,3,NC(=O)c1cccc(B(O)O)c1.O=C1[C@@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1c1ccc(I)cc1F>>NC(=O)c1cccc(-c2ccc(N3CC[C@H](NS(=O)(=O)c4ccc5cc(Cl)ccc5c4)C3=O)c(F)c2)c1 -US06060477,7,CCOc1ccc([N+](=O)[O-])cc1-c1nc2cccnc2c(=O)[nH]1>>CCOc1ccc(N)cc1-c1nc2cccnc2c(=O)[nH]1 -US20090036474A1,6,COc1cc2ncnc(Oc3cnn(CC(=O)Nc4ccc(CN(C)C(=O)OC(C)(C)C)cc4)c3)c2cc1OC>>CNCc1ccc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)cc1 -US20060089392A1,1,CCOC(=O)C1CCNCC1.CN(C)C(=O)c1cc(Cl)ccc1[N+](=O)[O-]>>CCOC(=O)C1CCN(c2ccc([N+](=O)[O-])c(C(=O)N(C)C)c2)CC1 -US08084463B2,1,O=C(CBr)Nc1ccon1.O[C@H]1CN2CCC1CC2>>O=C(C[N+]12CCC(CC1)[C@@H](O)C2)Nc1ccon1 -US09079866B2,3,Nc1cnc(-c2ccc(Br)cc2F)cn1.OB(O)c1ccc(F)cc1F>>Nc1cnc(-c2ccc(-c3ccc(F)cc3F)cc2F)cn1 -US20150266872A1,2,C1O[C@@H]2CN[C@H]1C2.CCOC(=O)c1nnc2c(Cl)cc(C(F)(F)F)cn12>>O=C(c1nnc2c(Cl)cc(C(F)(F)F)cn12)N1C[C@@H]2C[C@H]1CO2 -US20110263628A1,3,C=CC[C@@H](C(=O)OC(C)C)[C@H](O)C(=O)OC(C)C.CCOc1ccc(Br)cc1>>CCOc1ccc(/C=C/C[C@@H](C(=O)OC(C)C)[C@H](O)C(=O)OC(C)C)cc1 -US20030149051A1,3,C[Mg+].Cc1noc(-c2ccccc2)c1C=O>>Cc1noc(-c2ccccc2)c1C(C)O -US05728650,7,CCOP(=O)(OCC)C(CCCCNC(=O)c1ccccc1)P(=O)(OCC)OCC>>CCOP(=O)(OCC)C(CCCCNCc1ccccc1)P(=O)(OCC)OCC -US20150152096A1,10,CCOC(=O)C1=C(C)NC(c2cscn2)=NC1c1ccc(Cl)cc1Cl.O=C1CCC(=O)N1Br>>CCOC(=O)C1=C(CBr)NC(c2cscn2)=NC1c1ccc(Cl)cc1Cl -US07579354B2,7,CCCn1c(=O)c2[nH]c(C34CCC(C=CC(=O)O)(CC3)CC4)nc2n(CCC)c1=O>>CCCn1c(=O)c2[nH]c(C34CCC(CCC(=O)O)(CC3)CC4)nc2n(CCC)c1=O -US04814112,1,CCCCCCCCCCCCCCCC(=O)Cl.c1nc[nH]n1>>CCCCCCCCCCCCCCCC(=O)n1cncn1 -US06624158B2,6,CC(C)CS(=O)(=O)NCc1nc(NCC(c2ccccc2)c2ccccc2)c2ncn(C3CCCCO3)c2n1>>CC(C)CS(=O)(=O)NCc1nc(NCC(c2ccccc2)c2ccccc2)c2nc[nH]c2n1 -US20080161289A1,9,N.O=C(O)c1ccc(N2CCC(c3nc4c(s3)CCN(C3CCC3)CC4)CC2)cn1>>NC(=O)c1ccc(N2CCC(c3nc4c(s3)CCN(C3CCC3)CC4)CC2)cn1 -US07550467B2,2,C[C@H]1CN(CCCNC2COc3ccc(Br)cc3C2)[C@H](C)CN1C(=O)OC(C)(C)C.O=C=Nc1ccc(F)c(Cl)c1>>C[C@H]1CN(CCCN(C(=O)Nc2ccc(F)c(Cl)c2)C2COc3ccc(Br)cc3C2)[C@H](C)CN1C(=O)OC(C)(C)C -US20090105290A1,6,CCOC(=O)CC1(O)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(O)(CC(=O)O)CC1 -US20130045169A1,1,BrCCCCCC1OCCO1.CC(C)(C)OC(=O)NC(c1ccccc1)c1cccc(OCC(=O)O)c1>>CC(C)(C)OC(=O)NC(c1ccccc1)c1cccc(OCC(=O)OCCCCCC2OCCO2)c1 -US06255315B1,8,O=C(OO)c1cccc(Cl)c1.c1ccc(C2CCC3(CC2)OCCO3)nc1>>[O-][n+]1ccccc1C1CCC2(CC1)OCCO2 -US05210193,1,FC(F)(F)C1CNCCN1.O=C(O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2cc(N3CCNC(C(F)(F)F)C3)c(F)cc2c1=O -US20050192347A1,1,C1=COCCC1.CC(CO)(CCCCN)c1ccccc1>>CC(CCCCN)(COC1CCCCO1)c1ccccc1 -US08314126B2,1,BrCCC1OCCO1.CS(=O)(=O)c1cccc(C2CCNCC2)c1F>>CS(=O)(=O)c1cccc(C2CCN(CCC3OCCO3)CC2)c1F -US20150191478A1,3,CCOC(OCC)c1cc2cncc(I)c2o1.OB(O)c1cccc(OCc2ccccc2)c1>>CCOC(OCC)c1cc2cncc(-c3cccc(OCc4ccccc4)c3)c2o1 -US08415345B2,9,N.O=S(=O)(Nc1cccc(-c2nc(C3CCC3)sc2-c2ccnc(Cl)n2)c1Cl)c1c(F)cccc1F>>Nc1nccc(-c2sc(C3CCC3)nc2-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2Cl)n1 -US20050131014A1,1,Cc1ccc(CBr)cc1.O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(O)c1>>Cc1ccc(COc2cccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1 -US20080200541A1,1,O=C1NC(=O)c2ccccc21.OCc1cc2cc(Cl)cc(Br)c2o1>>O=C1c2ccccc2C(=O)N1Cc1cc2cc(Cl)cc(Br)c2o1 -US07851473B2,2,O=C=Nc1ccc(F)cc1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1ccc(F)cc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 -US20150152080A1,2,COC(=O)c1ccccc1CSc1ccc(C)cc1N.O=S(=O)(Cl)c1cc2ccccc2s1>>COC(=O)c1ccccc1CSc1ccc(C)cc1NS(=O)(=O)c1cc2ccccc2s1 -US08217032B2,7,O=C(c1ccc(OCCN2CCCCCC2)cc1)c1c(-c2c(F)cc(F)cc2F)ccc2cc(O)ccc12>>Oc1ccc2c(C(O)c3ccc(OCCN4CCCCCC4)cc3)c(-c3c(F)cc(F)cc3F)ccc2c1 -US20110230630A1,7,CCC1(C=C2Cc3c(cccc3-c3ccc(C(C)(C)C)cc3)C2=O)CCCCC1>>CCC1(CC2Cc3c(cccc3-c3ccc(C(C)(C)C)cc3)C2=O)CCCCC1 -US20060004046A1,1,CC[O-].N#Cc1cnc2ccc(I)cc2c1Cl>>CCOc1c(C#N)cnc2ccc(I)cc12 -US20140202537A1,3,CCCCCCCCOc1ccc(-c2ccc(C=O)s2)cc1.N#CCC(=O)O>>CCCCCCCCOc1ccc(-c2ccc(C=C(C#N)C(=O)O)s2)cc1 -US06498172B1,2,COC(=O)CCc1cccc(CNCc2ccc3c(c2)OCO3)c1.O=S(=O)(Cl)c1ccc(F)cc1>>COC(=O)CCc1cccc(CN(Cc2ccc3c(c2)OCO3)S(=O)(=O)c2ccc(F)cc2)c1 -US06002008,2,C[SiH](C)OC(C#CC(=O)O)C(C)(C)C.N#Cc1cnc2ccc(N)cc2c1Nc1cccc(Br)c1>>C[SiH](C)OC(C#CC(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(Br)c3)c2c1)C(C)(C)C -US08461330B2,3,CC1(C)OB(c2cnn(C3CCOC3)c2)OC1(C)C.Nc1ncc(Br)cn1>>Nc1ncc(-c2cnn(C3CCOC3)c2)cn1 -US20090318431A1,1,CN1C(=O)OCc2cc(N3C[C@H](COS(C)(=O)=O)OC3=O)ccc21.[N-]=[N+]=[N-]>>CN1C(=O)OCc2cc(N3C[C@H](CN=[N+]=[N-])OC3=O)ccc21 -US20090023740A1,2,Nc1nccs1.O=S(=O)(Cl)c1ccc(I)cc1>>O=S(=O)(Nc1nccs1)c1ccc(I)cc1 -US07371869B2,2,COC(=O)c1csc(NC(=O)[C@H](Cc2ccccc2)NC(=O)C(NC(=O)OC(C)(C)C)c2ccc3c(c2)ncn3C)n1>>COC(=O)c1csc(NC(=O)[C@H](Cc2ccccc2)N2C(=O)NC(c3ccc4c(c3)ncn4C)C2=O)n1 -US20040138230A1,7,CC1C(=O)Nc2ccc(C(=O)CCl)cc2C1C>>CC1C(=O)Nc2ccc(CCCl)cc2C1C -US04461895,1,COc1ccc(CC2NCCc3cc(OC)c(O)cc32)cc1O.ClCC1CC1>>COc1ccc(CC2c3cc(O)c(OC)cc3CCN2CC2CC2)cc1O -US06117893,1,O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1.OCc1cn2ccccc2n1>>O=C1SC(Cc2ccc(OCc3cn4ccccc4n3)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20090181950A1,3,C=CC(=O)OC.CC(C)(C)OC(=O)N1CCN(c2cccc3cc(I)cnc23)CC1>>COC(=O)/C=C/c1cnc2c(N3CCN(C(=O)OC(C)(C)C)CC3)cccc2c1 -US08969375B2,1,Brc1ccc2c(c1)NCC2.Fc1cccc(CBr)c1>>Fc1cccc(CN2CCc3ccc(Br)cc32)c1 -US20120202794A1,2,C=C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)c1cc(-c2ccc(F)cc2)on1>>C=C[C@H]1CN(C(=O)c2cc(-c3ccc(F)cc3)on2)[C@@H](CC(C)C)C(=O)N1 -US20090124602A1,9,CC(C)(C)OC(=O)N1CCN(c2cc3ccccc3c(C(=O)c3cccnc3F)n2)CC1.[NH4+]>>CC(C)(C)OC(=O)N1CCN(c2cc3ccccc3c(C(=O)c3cccnc3N)n2)CC1 -US20130065876A1,2,NN1CCOCC1.O=C(O)c1cnc(OCC(F)(F)F)c(C2CCCCC2)c1>>O=C(NN1CCOCC1)c1cnc(OCC(F)(F)F)c(C2CCCCC2)c1 -US20090197866A1,7,CN(C)CCCOc1cc2[nH]c(-c3nn(C4CCCCO4)cc3[N+](=O)[O-])nc2cc1F>>CN(C)CCCOc1cc2[nH]c(-c3nn(C4CCCCO4)cc3N)nc2cc1F -US20130216498A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2ccnc(-c3cnc4ccc(C#N)cn34)n2)C1>>N#Cc1ccc2ncc(-c3nccc(N[C@@H]4CCCNC4)n3)n2c1 -US04659370,2,CC(Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1)C(=O)Cl.OCCSCc1ccccc1>>CC(Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1)C(=O)OCCSCc1ccccc1 -US05635534,1,CC(=O)COc1ccc(CCOC(C)=O)cc1.NCC(O)c1cccc(Cl)c1>>CC(=O)OCCc1ccc(OCC(C)NCC(O)c2cccc(Cl)c2)cc1 -US08163744B2,6,COCCNC(=O)C1c2ccccc2C(=O)N(C(C(=O)OC)c2ccc(Cl)cc2)C1c1ccc(Cl)cc1>>COCCNC(=O)C1c2ccccc2C(=O)N(C(C(=O)O)c2ccc(Cl)cc2)C1c1ccc(Cl)cc1 -US20150266895A1,1,COC(=O)[C@@H](NCc1ccc(OC)cc1)c1ccccc1.COc1ccc(C=O)cc1>>COC(=O)[C@H](c1ccccc1)N(Cc1ccc(OC)cc1)Cc1ccc(OC)cc1 -US20140142303A1,1,O=C1COCCN1c1ccc(N2C[C@@H](CI)OC2=O)cc1.c1ccc(CNCc2ccccc2)cc1>>O=C1COCCN1c1ccc(N2C[C@@H](CN(Cc3ccccc3)Cc3ccccc3)OC2=O)cc1 -US08338605B2,1,Cc1ccc2c(Cl)ccnc2n1.Nc1cc(Br)ccc1Sc1ccccc1>>Cc1ccc2c(Nc3cc(Br)ccc3Sc3ccccc3)ccnc2n1 -US05234937,1,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.COCCOCCl>>COCCOCOc1c(C(C)(C)C)cc(C=O)cc1C(C)(C)C -US20140163033A1,9,N.N#Cc1cnc(Cl)nc1Cl>>N#Cc1cnc(N)nc1Cl -US20110301211A1,3,CCOC(=O)CCCc1ccc(Br)cc1.Cc1noc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c1NC(=O)OC(C)c1ccccc1Cl>>CCOC(=O)CCCc1ccc(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)cc1 -US04629735,6,CCOC(=O)c1ccccc1Nc1ccccc1OC>>CCOC(=O)c1ccccc1Nc1ccccc1O -US07635715B2,6,CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccc(-c3ccccc3)cc2C(C)(C)C1=O>>CC1(C)C(=O)C(C(=O)NCC(=O)O)=C(O)c2ccc(-c3ccccc3)cc21 -US04229363,6,COCc1cc(C(N)C(=O)OC)ccc1O>>COCc1cc(C(N)C(=O)O)ccc1O -US06096895,7,COC(=O)c1sccc1-n1c(OC)nn(C)c1=O>>COc1nn(C)c(=O)n1-c1ccsc1CO -US20080125436A1,2,COC(=O)c1ccnc(OC)c1.NN>>COc1cc(C(=O)NN)ccn1 -US08580842B2,2,CCOc1ccccc1C1(N)C(=O)Nc2ccc(OC)cc21.O=C(Cl)Oc1ccccc1>>CCOc1ccccc1C1(NC(=O)Oc2ccccc2)C(=O)Nc2ccc(OC)cc21 -US05607960,7,CC(=O)C=Cc1ccc2[nH]cc(C[C@H]3CCCN3CCC(=O)N(C)C)c2c1>>CC(=O)CCc1ccc2[nH]cc(C[C@H]3CCCN3CCC(=O)N(C)C)c2c1 -US20150191432A1,2,CCOC(=O)COc1cccc2ccccc12.NCC(O)CN1CCc2ccccc2C1>>O=C(COc1cccc2ccccc12)NCC(O)CN1CCc2ccccc2C1 -US20100216788A1,1,COCCBr.Cc1cc([N+](=O)[O-])ccc1Oc1cccc(O)c1>>COCCOc1cccc(Oc2ccc([N+](=O)[O-])cc2C)c1 -US20110237578A1,2,C[C@H](N)CO.Cc1ccc(-c2cc(C(=O)O)cc(-c3cc(C)ccc3C#N)c2)nc1>>Cc1ccc(-c2cc(C(=O)N[C@@H](C)CO)cc(-c3cc(C)ccc3C#N)c2)nc1 -US20060199817A1,3,Brc1ccc2c(NC3CCCCC3)nncc2c1.Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(NC3CCCCC3)nncc2c1 -US04284555,2,CN(C)C(=O)Cl.CN1CCc2cc(Cl)c(O)cc2[C@H](c2ccccc2)C1>>CN1CCc2cc(Cl)c(OC(=O)N(C)C)cc2[C@H](c2ccccc2)C1 -US08153644B2,2,O=C(Nc1ccc(N2CCNCC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F.O=C(O)Cc1nnn[nH]1>>O=C(Nc1ccc(N2CCN(C(=O)Cc3nnn[nH]3)CC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US07754717B2,6,COC(=O)c1cc(C(=O)Nc2cc(C(F)(F)F)ccc2F)ccc1C>>Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2F)cc1C(=O)O -US20110044943A1,1,CC(OS(C)(=O)=O)c1cc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)no1.Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F>>CC(c1cc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)no1)n1cc2nc(-c3cccc(F)c3F)nc-2cn1 -US20130045986A1,3,CC(C)(C)OC(=O)N1CCC(c2nc3cc(Br)ccc3o2)CC1.CC1(C)OB(c2ccc(C(N)=O)c(Cl)c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(c2nc3cc(-c4ccc(C(N)=O)c(Cl)c4)ccc3o2)CC1 -US20120264733A1,7,COCCCCNc1c(F)cccc1[N+](=O)[O-]>>COCCCCNc1c(N)cccc1F -US20110039852A1,2,CCNCc1cc(C(F)(F)F)ccc1-c1cc(C(C)(C)C(=O)OCC)ccc1OC.O=C(Cl)OCc1ccccc1>>CCOC(=O)C(C)(C)c1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)OCc2ccccc2)c1 -US20070123504A1,6,CCOC(=O)c1nc(-c2ccccc2)oc1Cl>>O=C(O)c1nc(-c2ccccc2)oc1Cl -US04663319,1,CI.O=C1CCNC(=O)C1=C1SC=CS1>>CN1CCC(=O)C(=C2SC=CS2)C1=O -US07585886B2,2,C[C@H](c1cccc2ccccc12)N(CC1CNCC1c1ccccc1)C(=O)OC(C)(C)C.O=C=Nc1ccccc1>>C[C@H](c1cccc2ccccc12)N(CC1CN(C(=O)Nc2ccccc2)CC1c1ccccc1)C(=O)OC(C)(C)C -US09079911B2,1,COc1ccc(C(=O)N2CC3CNCC3C2)c(-n2nccn2)c1.Cc1nc(Cl)ncc1F>>COc1ccc(C(=O)N2CC3CN(c4ncc(F)c(C)n4)CC3C2)c(-n2nccn2)c1 -US20100256097A1,1,CC(C)(O)c1cccc(Br)n1.NC(=O)c1cc(-c2ccccc2F)sc1N>>CC(C)(O)c1cccc(Nc2sc(-c3ccccc3F)cc2C(N)=O)n1 -US08445490B2,6,COC(=O)c1ccc(Nc2nc(NCCNCCN)nc(OCC(F)(F)F)n2)cc1>>NCCNCCNc1nc(Nc2ccc(C(=O)O)cc2)nc(OCC(F)(F)F)n1 -US06489485B2,2,CS(=O)(=O)Cl.Nc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1>>CS(=O)(=O)Nc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1 -US05123954,1,CC(C)c1cc(N)ccc1Cl.CC=CCCl>>CC=CCNc1ccc(Cl)c(C(C)C)c1 -US05709911,7,COC(=O)CC[C@@H]1CC[C@@H](c2cccc(F)c2F)CC1>>OCCC[C@@H]1CC[C@@H](c2cccc(F)c2F)CC1 -US20100016366A1,2,NCCCCCCCCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1.O=C(O)c1cc(Cl)c(O)c(Cl)c1>>O=C(Nc1ccccc1-c1ccccc1)OC1CCN(CCCCCCCCCNC(=O)c2cc(Cl)c(O)c(Cl)c2)CC1 -US20100016293A1,1,CN1CCNCC1.COc1nc2cc(Cl)ccc2nc1Cl>>COc1nc2cc(Cl)ccc2nc1N1CCN(C)CC1 -US20150105549A1,6,CCOC(=O)c1cnc(-c2ccsc2)n(CCOC)c1=O>>COCCn1c(-c2ccsc2)ncc(C(=O)O)c1=O -US20070167433A1,1,C=CCOc1ccc([C@H]2[C@H](O[Si](C(C)C)(C(C)C)C(C)C)CN(C(=O)OCc3ccccc3)C[C@@H]2O)cc1.COCCCN1C(=O)COc2ccc(CCl)cc21>>C=CCOc1ccc([C@H]2[C@H](O[Si](C(C)C)(C(C)C)C(C)C)CN(C(=O)OCc3ccccc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)C(=O)CO3)cc1 -US20120322788A1,7,CC(C)(C)OC(=O)N1CCC2(CC1)CNC(=O)C(F)(F)O2>>CC(C)(C)OC(=O)N1CCC2(CC1)CNCC(F)(F)O2 -US05707978,2,CCCCCCCCCCCCCCCCCCOC(CO)COC(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCCCCCCCCCCCCCCCCOC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)COS(=O)(=O)c1ccc(C)cc1 -US20120142646A1,2,O=C(Cl)OCc1ccccc1.O=C(OCc1ccccc1)N(CCC(=O)N(CCNCCc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1)C1CCCCC1)CCc1ccccc1>>O=C(OCc1ccccc1)N(CCC(=O)N(CCN(CCc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1)C(=O)OCc1ccccc1)C1CCCCC1)CCc1ccccc1 -US20070049593A1,2,COC(=O)C(C)(C)N.COc1ccc2c(c1)OCCn1c-2c(C2CCCCC2)c2ccc(C(=O)O)cc21>>COC(=O)C(C)(C)NC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCOc1cc(OC)ccc1-3 -US20140357614A1,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.CCCCNc1cc(Br)ccn1>>CCCCNc1cc(N2CC[C@@H](NC(=O)OC(C)(C)C)C2)ccn1 -US20150174089A1,6,CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)c1noc(=O)[nH]1>>C[C@H](C[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)c1noc(=O)[nH]1)C(=O)O -US08859541B2,2,CC(NC(=O)OC(C)(C)C)C(=O)O.Nc1cc2ccccc2c(Br)n1>>CC(NC(=O)OC(C)(C)C)C(=O)Nc1cc2ccccc2c(Br)n1 -US20100099665A1,1,BrCC1CC1.CC(C)(C)OC(=O)N1CCC(Sc2c[nH]c(=O)c3ccc(Br)cc23)CC1>>CC(C)(C)OC(=O)N1CCC(Sc2cn(CC3CC3)c(=O)c3ccc(Br)cc23)CC1 -US20150080365A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1ncsc1Br>>Cc1ncsc1N1CCN(C(=O)OC(C)(C)C)CC1 -US20110039852A1,2,CCNCc1ccc(OC)cc1-c1cc(CC(=O)OC)ccc1OC.O=C=NCc1ccccc1>>CCN(Cc1ccc(OC)cc1-c1cc(CC(=O)OC)ccc1OC)C(=O)NCc1ccccc1 -US20150210682A1,1,BrCCn1ccnc1.CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2CC>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCn3ccnc3)cc1CC2CC -US20110230462A1,1,Ic1c[nH]cn1.OB(O)c1cc(F)cc(F)c1F>>Fc1cc(F)c(F)c(-n2cnc(I)c2)c1 -US05122604,1,COc1ccc(CCl)cc1.O=C(O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1>>COc1ccc(COC(=O)[C@@H]2C[C@@H](O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)cc1 -US20100029707A1,2,CC(=O)Cl.CCc1nn2ccc3c(c2c1C(C)CN)CCO3>>CCc1nn2ccc3c(c2c1C(C)CNC(C)=O)CCO3 -US20150005347A1,1,Fc1ccc(CBr)cn1.O=C(N=c1cccc[nH]1)C(F)F>>O=C(N=c1ccccn1Cc1ccc(F)nc1)C(F)F -US20130029991A1,2,CCOC(=O)CN.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Br)cc2Cl)cc1>>CCOC(=O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Br)cc2Cl)cc1 -US20060100201A1,1,FC1CCCNC1.O=[N+]([O-])c1ccc(Cl)cc1F>>O=[N+]([O-])c1ccc(Cl)cc1N1CCCC(F)C1 -US07781591B2,3,CC(C)OB(OC(C)C)c1ccc(OCCCl)cc1.Cc1c(Nc2c(I)cncc2C#N)cc(Cl)c2[nH]ccc12>>Cc1c(Nc2c(C#N)cncc2-c2ccc(OCCCl)cc2)cc(Cl)c2[nH]ccc12 -US05478835,2,CC(C)c1cccc(C(C)C)c1N.Cc1ccc2c(c1)C(C(=O)O)c1ccccc1CO2>>Cc1ccc2c(c1)C(C(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1CO2 -US20150246902A1,2,CN.O=C(O)c1c(-c2ccc(F)cc2)oc2cc(N3CCCC3=O)c(Br)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N3CCCC3=O)c(Br)cc12 -US20100119503A1,1,CC1COCCC1=O.CCOC[C@]1(C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)CC[C@@H](N)C1>>CCOC[C@]1(C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)CC[C@@H](N[C@@H]2CCOCC2C)C1 -US20140018335A1,9,COc1cc2cc(-c3ccccc3)n(Cc3ccc(C(N)=O)o3)c2cc1Cl>>COc1cc2cc(-c3ccccc3)n(Cc3ccc(C#N)o3)c2cc1Cl -US08993614B2,2,CC(Cl)OC(=O)Cl.NCC(=O)OCc1ccccc1>>CC(Cl)OC(=O)NCC(=O)OCc1ccccc1 -US20150014671A1,3,Brc1ccc(I)cc1.Cc1cccnc1Br>>Cc1cccnc1-c1ccc(Br)cc1 -US04406897,2,CC(=O)OC(C)=O.NNc1nc(O)nc(-c2ccc(Cl)cc2)n1>>CC(=O)NNc1nc(O)nc(-c2ccc(Cl)cc2)n1 -US07173031B2,3,C[Si](C)(C)CCOCn1cc(Br)c2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc21.OB(O)c1ccncc1>>C[Si](C)(C)CCOCn1cc(-c2ccncc2)c2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc21 -US04134980,1,BrCCBr.COc1cc2nc[nH]c(=O)c2cc1OC>>COc1cc2ncn(CCBr)c(=O)c2cc1OC -US20100240653A1,3,CS(=O)(=O)c1cc(Br)ccc1C(=O)O.C[C@@H]1CCCN1CCc1ccc(B(O)O)cc1>>C[C@@H]1CCCN1CCc1ccc(-c2ccc(C(=O)O)c(S(C)(=O)=O)c2)cc1 -US20030069233A1,2,COc1ccc(N)cc1N1CCN(C(=O)OC(C)(C)C)CC1.Cc1c(S(=O)(=O)Cl)sc2ccc(Cl)cc12>>COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCN(C(=O)OC(C)(C)C)CC1 -US20030139464A1,6,CCOC(=O)C(CN1C(=O)c2cccc(F)c2C1=O)C1(C)OCCO1>>CCOC(=O)C(CN1C(=O)c2cccc(F)c2C1=O)C(C)=O -US20150133425A1,2,CC1(C)CCNC1.COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)O)C3>>COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)N1CCC(C)(C)C1)C3 -US06339045B1,6,CC(C)NC(=O)c1cc(N(C)Cc2ccccc2)cc(Oc2cccc(C(F)(F)F)c2)n1>>CNc1cc(Oc2cccc(C(F)(F)F)c2)nc(C(=O)NC(C)C)c1 -US20140192305A1,1,COc1cc(CC#N)ccc1O.OCCCCCCCCCCCBr>>COc1cc(CC#N)ccc1OCCCCCCCCCCCO -US20120208827A1,1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.COC(=O)c1ccc([N+](=O)[O-])c(F)c1>>COC(=O)c1ccc([N+](=O)[O-])c(NC[C@@H]2CCN(C(=O)OC(C)(C)C)C2)c1 -US20070099903A1,2,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc2oc(=O)[nH]c12.Fc1ccc(N2CCNCC2)cc1>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(c3ccc(F)cc3)CC2)cc2oc(=O)[nH]c12 -US07425554B2,6,CC1(C)CC(c2cc(-c3ccccn3)ccc2N2CCN(C(=O)OC(C)(C)C)CC2)CC(C)(C)C1>>CC1(C)CC(c2cc(-c3ccccn3)ccc2N2CCNCC2)CC(C)(C)C1 -US08507472B2,2,CC(Cl)CCC(=O)Cl.NN=C(c1ccccc1)c1ccccc1>>CC(Cl)CCC(=O)NN=C(c1ccccc1)c1ccccc1 -US20050070508A1,1,CNCCN.O=C(NCCN1CCOCC1)c1cccc2cc(Oc3cc(Cl)ncn3)ccc12>>CNCCNc1cc(Oc2ccc3c(C(=O)NCCN4CCOCC4)cccc3c2)ncn1 -US07700599B2,2,CNc1ccc(CN2CCN(C(=O)OC(C)(C)C)[C@@H](C)C2)cc1.O=C(O)c1ccc(-c2ccccn2)cc1>>C[C@H]1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4ccccn4)cc3)cc2)CCN1C(=O)OC(C)(C)C -US04495190,7,CCOC(=O)C(F)CCn1cnc2c(Cl)nc(N)nc21>>Nc1nc(Cl)c2ncn(CCC(F)CO)c2n1 -US04826971,2,CC1C(=O)NN1C(c1ccccc1)c1ccccc1.Cc1ccc(S(=O)(=O)N=C=O)cc1>>Cc1ccc(S(=O)(=O)NC(=O)N2C(=O)C(C)N2C(c2ccccc2)c2ccccc2)cc1 -US07470664B2,3,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)[C@@H]1C[C@@H](OC(=O)N2CCc3cccc(OS(=O)(=O)C(F)(F)F)c3C2)CN1C(=O)OC(C)(C)C>>C=Cc1cccc2c1CN(C(=O)O[C@@H]1C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1)CC2 -US04435406,1,Cc1ccc(CCl)nc1.Sc1nc2cc3c(cc2[nH]1)CCC3>>Cc1ccc(CSc2nc3cc4c(cc3[nH]2)CCC4)nc1 -US07495007B2,3,CCC(=O)C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12.CC[Mg+]>>CCC(O)(CC)C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12 -US20150087663A1,1,C[C@H](N)c1nc2cccc(Cl)c2c(=O)n1C1CC1.Cn1cnc(-c2c(N)ncnc2Cl)n1>>C[C@H](Nc1ncnc(N)c1-c1ncn(C)n1)c1nc2cccc(Cl)c2c(=O)n1C1CC1 -US20140357614A1,1,CC(C)CNc1cc(I)ccn1.CN1CCNCC1>>CC(C)CNc1cc(N2CCN(C)CC2)ccn1 -US20120172290A1,3,CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.CC(C)(C)c1ccc(C2=C(Br)CCC2=O)cc1>>CC(C)(C)OC(=O)Nc1ccc(C2=C(c3ccc(C(C)(C)C)cc3)C(=O)CC2)cc1 -US20060116368A1,2,Nc1ccc2c(c1)OCC(=O)N2.O=C(O)C1CCN(c2cccc(C(F)(F)F)c2)CC1>>O=C1COc2cc(NC(=O)C3CCN(c4cccc(C(F)(F)F)c4)CC3)ccc2N1 -US20100069388A1,6,CCOC(=O)/C=C/c1cnc(NCCNC(=O)OC(C)(C)C)c(Cl)c1>>CCOC(=O)/C=C/c1cnc(NCCN)c(Cl)c1 -US20120129840A1,3,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl.OB(O)c1cccc2ncccc12>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1cccc2ncccc12 -US08426429B2,1,CCCN.O=Cc1cc(Oc2cccc(NC(=O)OCc3ccccc3)c2)ccc1[N+](=O)[O-]>>CCCNCc1cc(Oc2cccc(NC(=O)OCc3ccccc3)c2)ccc1[N+](=O)[O-] -US07348323B2,6,CCOC(=O)c1cc2cc(N3CCN(C4CCCC4)CC3)ncc2[nH]1>>O=C(O)c1cc2cc(N3CCN(C4CCCC4)CC3)ncc2[nH]1 -US20040235754A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](COCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O -US20140315895A1,7,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CC)C(=O)OC)C1=O>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CC)CO)C1=O -US20070213359A1,2,NCc1cccc(Cl)c1.O=C(O)c1c[nH]c2ccccc12>>O=C(NCc1cccc(Cl)c1)c1c[nH]c2ccccc12 -US05554621,2,COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(N)c1.O=C(Cl)CCCl>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(NC(=O)CCCl)c1 -US07060831B2,9,COC(=O)[C@H](c1ccccc1Cl)N1Cc2ccsc2C(O)C1>>COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1 -US07595397B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCNCC(O)Cc1ccccc1>>CC(C)(C)OC(=O)N(CCO)CC(O)Cc1ccccc1 -US07592456B2,1,C[Si](C)(C)CCOCn1cnc2c(I)cccc21.O=S([O-])c1ccc2cc(-c3ccc(F)cc3)ccc2c1>>C[Si](C)(C)CCOCn1cnc2c(S(=O)(=O)c3ccc4cc(-c5ccc(F)cc5)ccc4c3)cccc21 -US20070232627A1,2,CC(C)c1ccc2c(Nc3cc(C(=O)O)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1.CC(N)c1cccnc1>>CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4cccnc4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1 -US06482950B1,1,CCC(Br)CC.COC(=O)c1ccc(O)cc1O>>CCC(CC)Oc1ccc(C(=O)OC)c(O)c1 -US06420396B1,6,CCOC(=O)CC(NS(=O)(=O)c1cccc(-c2cccc(Nc3nccs3)c2)c1)c1ccccc1>>O=C(O)CC(NS(=O)(=O)c1cccc(-c2cccc(Nc3nccs3)c2)c1)c1ccccc1 -US08173682B2,2,CCc1cc(-c2ccc(C(=O)O)s2)c(C)[nH]c1=O.c1ccc(CN2CCNCC2)cc1>>CCc1cc(-c2ccc(C(=O)N3CCN(Cc4ccccc4)CC3)s2)c(C)[nH]c1=O -US20120035237A1,1,BrCc1ccccc1Br.O=C(Nc1c(F)cccc1F)c1cc[nH]n1>>O=C(Nc1c(F)cccc1F)c1ccn(Cc2ccccc2Br)n1 -US20150065705A1,6,CC(C)(C)OC(=O)N1CC=C(c2ccc(F)cc2)[C@H](OC(=O)C(C)(C)C)C1>>CC(C)(C)C(=O)O[C@@H]1CNCC=C1c1ccc(F)cc1 -US06395905B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccc(N)cc1>>CC(C)(C)OC(=O)NCCc1ccc(N)cc1 -US08349836B2,1,NCc1cccnc1.O=c1[nH]nc(Cl)c2cc(Br)ccc12>>O=c1[nH]nc(Cl)c2cc(NCc3cccnc3)ccc12 -US06638929B2,7,C[Si](C)(C)CCOCn1cc(C#N)c(=O)c2cc([N+](=O)[O-])c(NCCN3CCOCC3)cc21>>C[Si](C)(C)CCOCn1cc(C#N)c(=O)c2cc(N)c(NCCN3CCOCC3)cc21 -US07390916B2,3,CC(=O)Nc1ccc(C=O)cc1.CCOC(=O)CC#N>>CCOC(=O)C(C#N)=Cc1ccc(NC(C)=O)cc1 -US08399503B2,6,CCCCC1(N(C)C)CCC2(CC1)OCCO2>>CCCCC1(N(C)C)CCC(=O)CC1 -US20130109661A1,3,CC1CCCN1c1cccc(Nc2cc(Cl)nn3ccnc23)n1.OB(O)c1ccccc1>>CC1CCCN1c1cccc(Nc2cc(-c3ccccc3)nn3ccnc23)n1 -US20090270412A1,2,CN1CCc2c(n(CC(=O)O)c3cccc(Cl)c23)C1.Nc1ccc(F)cc1>>CN1CCc2c(n(CC(=O)Nc3ccc(F)cc3)c3cccc(Cl)c23)C1 -US20150148376A1,1,CCOC(=O)c1ccc2c(n1)CCCC2N(CCc1cc(F)ccc1O)C(=O)OC(C)(C)C.ClCc1ccc(-c2nc3cc(Cl)ccc3o2)cc1>>CCOC(=O)c1ccc2c(n1)CCCC2N(CCc1cc(F)ccc1OCc1ccc(-c2nc3cc(Cl)ccc3o2)cc1)C(=O)OC(C)(C)C -US20030055263A1,1,Clc1nccc(-c2ccc3ccccc3c2)n1.Nc1ccccc1C(=O)O>>O=C(O)c1ccccc1Nc1nccc(-c2ccc3ccccc3c2)n1 -US09090599B2,2,NCc1nc(C(F)(F)F)no1.O=C(O)c1cnc(OCC2CCOC2)c(-c2ccc(Cl)cc2)c1>>O=C(NCc1nc(C(F)(F)F)no1)c1cnc(OCC2CCOC2)c(-c2ccc(Cl)cc2)c1 -US20150087639A1,7,CCCCN(CCCC)c1ccc([N+](=O)[O-])cc1F>>CCCCN(CCCC)c1ccc(N)cc1F -US20060217380A1,6,C[Si](C)(C)C#Cc1ccc(NCCN2CCOCC2)nc1>>C#Cc1ccc(NCCN2CCOCC2)nc1 -US08143263B2,2,COC(=O)[C@@H](O)COCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.Cc1ccc(N)nc1>>Cc1ccc(NC(=O)[C@@H](O)COCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)nc1 -US07700599B2,7,C[C@H]1CN(Cc2ccc([N+](=O)[O-])cc2)CCN1C(=O)OC(C)(C)C>>C[C@H]1CN(Cc2ccc(N)cc2)CCN1C(=O)OC(C)(C)C -US20100056516A1,6,COC(=O)c1ccc(C(=O)OC)c(-c2cccnc2)c1>>COC(=O)c1ccc(C(=O)O)cc1-c1cccnc1 -US20080317767A1,6,CCCCCCCCCCCCCCCCCCCCOC(=O)OC[C@@H](COCc1ccc(OC)cc1)OC(=O)OCCCCCCCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCCCCCCOC(=O)OC[C@@H](CO)OC(=O)OCCCCCCCCCCCCCCCCCCCC -US20100234351A1,6,CC(C)(COCCO)NC(=O)OC(C)(C)C>>CC(C)(N)COCCO -US20060122168A1,1,C=CCBr.C[C@H]1Oc2ccc(F)cc2NC(=O)[C@H]1NC(=O)OC(C)(C)C>>C=CCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)Oc2ccc(F)cc21 -US20080027112A1,1,CCOC(=O)CCCCBr.COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1O>>CCOC(=O)CCCCOc1c(OC)ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc12 -US08604021B2,1,CS(=O)(=O)c1ccc(F)cc1F.NC1CCCc2ccccc21>>CS(=O)(=O)c1ccc(F)cc1NC1CCCc2ccccc21 -US08470816B2,6,CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(Cl)c(Cl)c1>>CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1 -US20050059705A1,1,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cc2cc(Oc3ccc(C(C)(C)C)cc3)ccc2cn1.OCC1CCCC1>>COC(=O)[C@H](Cc1ccc(OCC2CCCC2)cc1)NC(=O)c1cc2cc(Oc3ccc(C(C)(C)C)cc3)ccc2cn1 -US20050038072A1,1,CSc1ccccc1CO.O=C1CCNCC1C(c1ccccc1)c1ccccc1>>CSc1ccccc1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1 -US04362738,2,CCN(Cc1cc(C(=O)OCCCN2CCN(CCO)CC2)cc(Br)c1N)C1CCCCC1.O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl>>CCN(Cc1cc(C(=O)OCCCN2CCN(CCOC(=O)Cc3ccccc3Nc3c(Cl)cccc3Cl)CC2)cc(Br)c1N)C1CCCCC1 -US20140023642A1,2,O=C(O)c1cccc(Cn2c(=O)[nH]c3c(Cl)cccc3c2=O)c1.c1cnc(N2CCNCC2)nc1>>O=C(c1cccc(Cn2c(=O)[nH]c3c(Cl)cccc3c2=O)c1)N1CCN(c2ncccn2)CC1 -US20070208033A1,1,CCCNCCC.O=Cc1ccc(O)cc1>>CCCN(CCC)Cc1ccc(O)cc1 -US20150045351A1,6,CN1CC2CN(C(=O)OC(C)(C)C)CCc3c(Br)ccc1c32>>CN1CC2CNCCc3c(Br)ccc1c32 -US08349831B2,1,COC(=O)C1CCN(c2cc(C=O)ccc2Cl)CC1.C[C@@H](N)c1ccccc1>>COC(=O)C1CCN(c2cc(CN[C@H](C)c3ccccc3)ccc2Cl)CC1 -US04808715,2,NCCCCl.O=S(=O)(Cl)c1ccc(Nc2ncnc3cc(Cl)ccc23)cc1>>O=S(=O)(NCCCCl)c1ccc(Nc2ncnc3cc(Cl)ccc23)cc1 -US20120157476A1,2,N[C@@H]1CCCC[C@H]1O.O=C(O)c1cc(-c2ccc(Cl)cc2)c(OCC(F)(F)F)nn1>>O=C(N[C@@H]1CCCC[C@H]1O)c1cc(-c2ccc(Cl)cc2)c(OCC(F)(F)F)nn1 -US05834501,1,CN.O=[N+]([O-])c1ccc(Cl)nc1Cl>>CNc1nc(Cl)ccc1[N+](=O)[O-] -US07544703B2,1,Fc1cc(CCl)ccn1.O=C(O)c1cccnc1S>>O=C(O)c1cccnc1SCc1ccnc(F)c1 -US20100292222A1,1,BrCc1ccccc1.Oc1ccc(Br)cc1F>>Fc1cc(Br)ccc1OCc1ccccc1 -US20140107094A1,6,COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1>>Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(O)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1 -US06054593,6,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C>>CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C -US20120329782A1,3,CN(C)C=O.Cc1c(Br)c(C(F)F)nn1C1CCCCO1>>Cc1c(C=O)c(C(F)F)nn1C1CCCCO1 -US20050176689A1,6,CC(C)c1cc(C(=O)Oc2ccc(C=CC(=O)OCc3ccccc3)cc2)cc2c1OC(C)(C)CC2(C)C>>CC(C)c1cc(C(=O)Oc2ccc(C=CC(=O)O)cc2)cc2c1OC(C)(C)CC2(C)C -US20120101131A1,2,CCOC(=O)Cn1ncc2c1CCCC2NS(=O)(=O)c1cccc(N)c1.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)Cn1ncc2c1CCCC2NS(=O)(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 -US20110015175A1,1,C=C(CCCl)CC(c1ccc(F)cc1)c1nc(Nc2ccc(-n3ncnc3C)c(F)c2)n[nH]1>>C=C1CCn2nc(Nc3ccc(-n4ncnc4C)c(F)c3)nc2C(c2ccc(F)cc2)C1 -US20090118284A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Fc1cc(I)ccc1Br>>CC(C)(C)OC(=O)N1CC=C(c2ccc(Br)c(F)c2)CC1 -US20070078121A1,2,CC(C)(C)c1ncc(N)c(-c2ccccc2)n1.O=C=Nc1cccc(Oc2ccccc2)c1>>CC(C)(C)c1ncc(NC(=O)Nc2cccc(Oc3ccccc3)c2)c(-c2ccccc2)n1 -US20070275968A1,1,BrCCOC1CCCCO1.Ic1cn[nH]c1>>Ic1cnn(CCOC2CCCCO2)c1 -US06426345B1,7,O=C(Nc1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1)Nc1ccccc1[N+](=O)[O-]>>Nc1ccccc1NC(=O)Nc1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1 -US05369121,2,CN=C=O.COC(=O)C12COc3ccccc3C1NN(C(=O)Nc1ccc(C(F)(F)F)cc1)C2>>CNC(=O)N1C2c3ccccc3OCC2(C(=O)OC)CN1C(=O)Nc1ccc(C(F)(F)F)cc1 -US06432950B1,1,Clc1cc2c(Cl)nc(-c3cccnc3)nc2s1.NCc1ccc(Cl)c(Cl)c1>>Clc1cc2c(NCc3ccc(Cl)c(Cl)c3)nc(-c3cccnc3)nc2s1 -US20030153506A1,2,CC(C)C[C@H](N)C(=O)NCc1ccc(C#N)cc1.COC(=O)c1cccc(CS(=O)(=O)N[C@@H](C(=O)O)C(C)C)c1>>COC(=O)c1cccc(CS(=O)(=O)N[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)NCc2ccc(C#N)cc2)C(C)C)c1 -US20100256092A1,6,CCOC(=O)CC1OB(O)c2cc(Oc3ccncn3)ccc21>>O=C(O)CC1OB(O)c2cc(Oc3ccncn3)ccc21 -US20140179690A1,2,CC(C)(C)OC(=O)NC1=N[C@@]2(c3cc(N)cc(F)c3F)CO[C@H](C(F)F)[C@H]2CS1.COc1cnc(C(=O)O)cn1>>COc1cnc(C(=O)Nc2cc(F)c(F)c([C@]34CO[C@H](C(F)F)[C@H]3CSC(NC(=O)OC(C)(C)C)=N4)c2)cn1 -US20140163001A1,2,CC(C)(C)n1ncc(C2=NC(C(=O)O)CS2)c1-c1ccc(F)cc1.NCCC1CCOCC1>>CC(C)(C)n1ncc(C2=NC(C(=O)NCCC3CCOCC3)CS2)c1-c1ccc(F)cc1 -US05457106,2,CC(=O)Cl.c1ccc(CNCCCSc2ccncc2)nc1>>CC(=O)N(CCCSc1ccncc1)Cc1ccccn1 -US04073912,1,O=C(O)c1ccccc1I.Sc1ccc2ccccc2c1>>O=C(O)c1ccccc1Sc1ccc2ccccc2c1 -US05559113,2,O=C=NC(=O)c1ccccc1.OCCCc1c[nH]cn1>>O=C(NC(=O)c1ccccc1)OCCCc1c[nH]cn1 -US20110130402A1,2,CCOC(=O)CSc1cnc(N)s1.CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1>>CCOC(=O)CSc1cnc(NC(=O)C(CC2CCCC2)c2ccc(S(C)(=O)=O)cc2)s1 -US20060211698A1,4,Nc1ccc(Br)cc1C=O.O=CCc1ccccc1>>Brc1ccc2ncc(-c3ccccc3)cc2c1 -US20110275627A1,3,C#CCC(C)(C)C(=O)OCC.CC(C)(C)C(=O)Cl>>CCOC(=O)C(C)(C)CC#CC(=O)C(C)(C)C -US20100190764A1,6,COC(=O)C1CN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)C1>>O=C(O)C1CN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)C1 -US08183369B2,2,O=C(C1CC1)N1CCNCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCN(C(=O)C2CC2)CC1 -US20100029707A1,7,CCC(=O)NC/C=C1\CCc2ncc3c(c21)CCO3>>CCC(=O)NCCC1CCc2ncc3c(c21)CCO3 -US08431695B2,3,CC(C)(C)OC(=O)N1CCc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1.Nc1ncnn2c(Br)ccc12>>CC(C)(C)OC(=O)N1CCc2ccc(-c3ccc4c(N)ncnn34)cc2C1 -US20130095085A1,1,C=C(C)[C@@H](CC=C(C)C)C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O>>CC(C)=CC[C@H]1C[C@@]23C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c4ccc(O)c(O)c4)=C2OC1(C)C)C3=O -US06362336B1,1,COc1cc2c(Cl)ncnc2cc1OCCn1cncn1.Nc1ccc(Br)cc1F>>COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCn1cncn1 -US04925939,9,CCOC(=O)C1CN(c2ccc(OC)cc2)CC1=O>>COc1ccc(N2CCC(=O)C2)cc1 -US06531502B1,3,COc1cc(C)c(C=O)cc1C(C)C.O=C1Cc2cc(Br)ccc2N1>>COc1cc(C)c(C=C2C(=O)Nc3ccc(Br)cc32)cc1C(C)C -US04273773,7,CCOC(CN1C(=O)c2ccccc2C1C(C)[N+](=O)[O-])OCC>>CCOC(CN1C(=O)c2ccccc2C1C(C)N)OCC -US05635534,1,COC(=O)Cc1ccc(OCC(C)=O)c(O)c1.NCC(O)c1cccc(Cl)c1>>COC(=O)Cc1ccc(OCC(C)NCC(O)c2cccc(Cl)c2)c(O)c1 -US20080269284A1,6,CC(C)OC(=O)N1c2ccc(C(F)(F)F)cc2[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C3CCN(C(=O)OC(C)(C)C)CC3)n2)C[C@@H]1C>>CC(C)OC(=O)N1c2ccc(C(F)(F)F)cc2[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C3CCNCC3)n2)C[C@@H]1C -US08637221B2,2,C=C(C)C(=O)OC(=O)C(=C)C.NCCN>>C=C(C)C(=O)NCCN -US05753664,1,CC(C)(C)n1ncc(N(CCCO)Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)c(Cl)c1=O>>CC(C)(C)n1ncc2c(c1=O)OCCCN2Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1 -US20150105404A1,2,CNOC.O=C(O)c1ccnc(C(F)(F)F)c1>>CON(C)C(=O)c1ccnc(C(F)(F)F)c1 -US04762844,7,Cc1c(F)cc(C(=O)O)cc1[N+](=O)[O-]>>Cc1c(N)cc(C(=O)O)cc1F -US20100216746A1,9,N.O=[N+]([O-])c1cc(F)c(Br)cc1Oc1c(Cl)ccc(CBr)c1F>>NCc1ccc(Cl)c(Oc2cc(Br)c(F)cc2[N+](=O)[O-])c1F -US20140357641A1,1,C[O-].Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCC2CC(Br)=NO2)CCC3)cc1>>COC1=NOC(CCCCN2CCCc3nc(-c4ccc(C)cc4)c(-c4ccc(C)cc4)nc32)C1 -US20120052130A1,1,CC(C)(C)[Si](C)(C)OCCSc1ccc2c(c1)CCN2.CC(C)OC(=O)N1CCC(Oc2cc(Cl)ncn2)CC1>>CC(C)OC(=O)N1CCC(Oc2cc(N3CCc4cc(SCCO[Si](C)(C)C(C)(C)C)ccc43)ncn2)CC1 -US06143779,3,CCOc1ccc(C=O)cc1OC.O=C1COc2cc(O)ccc21>>CCOc1ccc(C=C2Oc3cc(O)ccc3C2=O)cc1OC -US20060257987A1,1,CCc1ccc(O)c(C(C)(C)c2ccccc2)c1.COC(=O)CCc1ccc(OCC[C@H](C)OS(C)(=O)=O)cc1C>>CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)OC)c(C)c2)c(C(C)(C)c2ccccc2)c1 -US20080194549A1,8,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CO)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C=O)C(C)C)ccc1OC -US07122543B2,2,COC1=C(OC)C(=O)C(Cc2ccc(-c3ccccc3OC)c(C(=O)O)c2)=C(C)C1=O.COc1ccc(N)cc1>>COC1=C(OC)C(=O)C(Cc2ccc(-c3ccccc3OC)c(C(=O)Nc3ccc(OC)cc3)c2)=C(C)C1=O -US05310743,2,O=C(N(Cc1ccnc2ccccc12)[C@H]1CCN[C@H](Cc2ccccc2)C1)C(F)(F)F.O=C(O)Cc1ccc(Cl)cc1>>O=C(Cc1ccc(Cl)cc1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1 -US20100261719A1,3,C#Cc1cc(C=O)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F.Cn1cnc(Br)c1>>C[C@H]1CN(c2c(C=O)cc(C#Cc3cn(C)cn3)c(F)c2F)C[C@@H](C)O1 -US20030055057A1,2,COCCCN.COCCCn1c(-c2ccc(C(C)(C)C)cc2)nc2ccc(OCCCCCC(=O)OC)cc21>>COCCCNC(=O)CCCCCOc1ccc2nc(-c3ccc(C(C)(C)C)cc3)n(CCCOC)c2c1 -US20150038488A1,1,C[C@@H](Oc1cc(-c2ccc(N3CCNCC3)cn2)cc2ncsc12)[C@H]1CNC(=O)C1.O=C1CCOCC1>>C[C@@H](Oc1cc(-c2ccc(N3CCN(C4CCOCC4)CC3)cn2)cc2ncsc12)[C@H]1CNC(=O)C1 -US20050101618A1,1,Cc1cc(N)ccc1Oc1cccnc1.O=C(CCl)NCC#Cc1ccc2ncnc(Cl)c2c1>>Cc1cc(Nc2ncnc3ccc(C#CCNC(=O)CCl)cc23)ccc1Oc1cccnc1 -US20090062348A1,6,Nc1ccc(C(=O)NCc2cc3ccc(OCc4ccccc4)cc3o2)c(N)n1>>Nc1ccc(C(=O)NCc2cc3ccc(O)cc3o2)c(N)n1 -US08076345B2,1,Cc1ccc(N2CCc3ncnc(Cl)c3C2)c(C#N)c1.N[C@H](CO)c1ccc(C(F)(F)F)nc1>>Cc1ccc(N2CCc3ncnc(N[C@H](CO)c4ccc(C(F)(F)F)nc4)c3C2)c(C#N)c1 -US06960578B2,3,C#Cc1ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c1.FC(F)(F)Oc1ccc(I)cc1>>CC(C)(C)OC(=O)Nc1ccc(C#Cc2ccc(OC(F)(F)F)cc2)cc1[N+](=O)[O-] -US08536183B2,2,C[C@H]1CNCCN1C(=O)OC(C)(C)C.O=S(=O)(Cl)c1cc(C(F)(F)F)ccc1Br>>C[C@H]1CN(S(=O)(=O)c2cc(C(F)(F)F)ccc2Br)CCN1C(=O)OC(C)(C)C -US20100087427A1,7,CCOC(=O)[C@H]1CN(C(=O)OC(C)(C)C)C[C@H]1c1cccc(C(C)C)c1>>CC(C)c1cccc([C@@H]2CN(C(=O)OC(C)(C)C)C[C@@H]2CO)c1 -US20150099732A1,3,CN1CCN(c2ncc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.Cc1cccc2c(=O)[nH]c(Cl)cc12>>Cc1cccc2c(=O)[nH]c(-c3cnc(N4CCN(C)CC4)nc3)cc12 -US06693101B2,7,Cc1ncc(C=CCC(=O)CCCCCOCc2ccccc2)cn1>>Cc1ncc(C=CC[C@H](O)CCCCCOCc2ccccc2)cn1 -US20120157476A1,3,Fc1cnc(Cl)nc1Cl.OB(O)c1ccc(Cl)cc1>>Fc1cnc(Cl)nc1-c1ccc(Cl)cc1 -US20120232070A1,4,CC(C)(C)c1cccc(S(=O)(=O)n2c(CC(N)=S)cc3cc(C(F)(F)F)ccc32)c1.CCOC(=O)C(=O)CBr>>CCOC(=O)c1csc(Cc2cc3cc(C(F)(F)F)ccc3n2S(=O)(=O)c2cccc(C(C)(C)C)c2)n1 -US05360802,7,Cc1ccc([N+](=O)[O-])cc1C(=O)NS(C)(=O)=O>>Cc1ccc(N)cc1C(=O)NS(C)(=O)=O -US20100035871A1,2,CN1CC(CO)Oc2c(Br)cccc21.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC2CN(C)c3cccc(Br)c3O2)cc1 -US20020156081A1,7,O=[N+]([O-])c1cc(Cl)cc(Cl)c1O>>Nc1cc(Cl)cc(Cl)c1O -US08921576B2,2,C1CNC1.CC(=O)N1CCC2(C1)CN(C(=O)Nc1ncc(Cl)s1)c1ccc(CCC(=O)O)cc12>>CC(=O)N1CCC2(C1)CN(C(=O)Nc1ncc(Cl)s1)c1ccc(CCC(=O)N3CCC3)cc12 -US20080255152A1,1,CC(C)(C)OC(=O)NCCc1ccc(O)cc1.NC(=O)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)NCCc1ccc(Oc2ccc(C(N)=O)cn2)cc1 -US08779144B2,7,CC(=O)OCC(COC(C)=O)n1ccc2c([N+](=O)[O-])cccc2c1=O>>CC(=O)OCC(COC(C)=O)n1ccc2c(N)cccc2c1=O -US20150057311A1,2,CCCCCCCCCCCC(=O)NN.CCOC(=O)c1c(O)c2ccc(Cl)cc2n(CC)c1=O>>CCCCCCCCCCCC(=O)NNC(=O)c1c(O)c2ccc(Cl)cc2n(CC)c1=O -US06331637B1,2,Cc1noc(N)c1C.O=S(=O)(Cl)c1c(Cc2ccc3c(c2)OCO3)sc2ccccc12>>Cc1noc(NS(=O)(=O)c2c(Cc3ccc4c(c3)OCO4)sc3ccccc23)c1C -US20110021523A1,2,Nc1ccc(Br)cc1C(=O)c1ccncc1.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>O=C(c1ccncc1)c1cc(Br)ccc1NS(=O)(=O)c1ccc(OC(F)(F)F)cc1 -US07119120B2,2,Nc1cccc(C(F)(F)F)c1.O=C=Nc1ccc(F)c([N+](=O)[O-])c1>>O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(F)c([N+](=O)[O-])c1 -US20050107381A1,1,CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ccc(CCC(C)=O)cn1.CCCN>>CCCNC(C)CCc1ccc(NC(=O)C(CCC)NC(=O)Cc2cc(F)cc(F)c2)nc1 -US20090253689A1,6,CCOC(=O)c1cnc2cc(CNC(=O)OC(C)(C)C)c(-c3ccc(Cl)cc3Cl)cn12>>CC(C)(C)OC(=O)NCc1cc2ncc(C(=O)O)n2cc1-c1ccc(Cl)cc1Cl -US06005116,1,CC(C)(C)OC(=O)NCCO.Cc1ccc(-c2onc(O)c2C(C)C)cc1>>Cc1ccc(-c2onc(OCCNC(=O)OC(C)(C)C)c2C(C)C)cc1 -US04000275,2,CCOC(=O)CCCCCC(=O)Cl.O=c1c2ccccc2nc2[nH]c3ccccc3n12>>CCOC(=O)CCCCCC(=O)n1c2ccccc2n2c(=O)c3ccccc3nc12 -US04289775,8,CCSCCNc1ncc(N)c(O)n1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)CCNc1ncc(N)c(O)n1 -US07998978B2,2,COc1ccc(CC(=O)O)cc1.Nc1cc2cc(-c3cn[nH]c3)ccc2cn1>>COc1ccc(CC(=O)Nc2cc3cc(-c4cn[nH]c4)ccc3cn2)cc1 -US08501732B2,1,Nc1ccccc1.O=C(O)c1ccc(C(F)(F)F)nc1Cl>>O=C(O)c1ccc(C(F)(F)F)nc1Nc1ccccc1 -US20070299068A1,6,COc1ccc2cc(-c3ccc(NC(=O)OC(C)C)cc3)n(C(=O)OC(C)(C)C)c2c1>>COc1ccc2cc(-c3ccc(NC(=O)OC(C)C)cc3)[nH]c2c1 -US20050261298A1,6,COC(=O)COc1ccc(Br)cc1C=C1SC(=Nc2ccc(Cl)cc2)NC1=O>>O=C(O)COc1ccc(Br)cc1C=C1SC(=Nc2ccc(Cl)cc2)NC1=O -US20100093825A1,1,CC(C)(C)OC(=O)C12CCC(N)(CC1)CC2.N#C[C@@H]1CCCN1C(=O)CBr>>CC(C)(C)OC(=O)C12CCC(NCC(=O)N3CCC[C@H]3C#N)(CC1)CC2 -US07345038B2,1,CC1CN1.ClCc1ccc(Cl)nc1>>CC1CN1Cc1ccc(Cl)nc1 -US07579354B2,8,CCCn1c(=O)c2[nH]c(C34CCC(CO)(CC3)CC4)nc2n(CCC)c1=O>>CCCn1c(=O)c2[nH]c(C34CCC(C=O)(CC3)CC4)nc2n(CCC)c1=O -US20020019371A1,2,CCOC(=O)Cc1cccc(N)c1.O=CO>>CCOC(=O)Cc1cccc(NC=O)c1 -US05693635,7,O=C(c1ccc([N+](=O)[O-])cc1)N1CCc2ccccc2-c2ccccc21>>Nc1ccc(C(=O)N2CCc3ccccc3-c3ccccc32)cc1 -US20100331293A1,3,CS(=O)c1ccccc1B(O)O.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>Cc1c(-c2ccccc2S(C)=O)nc2cc(F)cc(F)c2c1Cl -US20140171417A1,7,Cn1c(=O)c2c(-c3cccc(F)c3)n3c(c2n(C)c1=O)C(c1nc(Cl)cs1)=CC(CO)C3>>Cn1c(=O)c2c(-c3cccc(F)c3)n3c(c2n(C)c1=O)C(c1nc(Cl)cs1)CC(CO)C3 -US20070213359A1,1,CC(=O)c1c[nH]c2ncccc12.ClCCCI>>CC(=O)c1cn(CCCCl)c2ncccc12 -US20150266859A1,6,COC(=O)c1ccc(N(C(=O)OC(C)(C)C)C(CC(C)C)c2ccc(-n3cc(C(F)(F)F)cn3)nc2)nc1>>COC(=O)c1ccc(NC(CC(C)C)c2ccc(-n3cc(C(F)(F)F)cn3)nc2)nc1 -US08344027B2,1,CNCCc1ccccc1.COC(=O)CCCCCCCC=O>>COC(=O)CCCCCCCCN(C)CCc1ccccc1 -US20090082311A1,1,CC1=NC(CCc2ccc(-c3ccc(Br)cc3F)cc2)(COP(=O)(C(C)(C)C)C(C)(C)C)CO1.Sc1ccccc1>>CC1=NC(CCc2ccc(-c3ccc(Sc4ccccc4)cc3F)cc2)(COP(=O)(C(C)(C)C)C(C)(C)C)CO1 -US20110086834A1,1,Brc1ccc2c(c1)NCC2.Nc1nccc(Cl)n1>>Nc1nccc(N2CCc3ccc(Br)cc32)n1 -US20040259912A1,2,CCC(=O)c1cc(N)ccc1OCc1ccc(C(C)C)cc1.COc1ccc(N=C=O)cc1>>CCC(=O)c1cc(NC(=O)Nc2ccc(OC)cc2)ccc1OCc1ccc(C(C)C)cc1 -US06987114B1,1,Cc1cc(C)cc(Oc2[nH]c(=O)[nH]c(=O)c2C(C)C)c1.Fc1cc(F)cc(CBr)c1>>Cc1cc(C)cc(Oc2c(C(C)C)c(=O)[nH]c(=O)n2Cc2cc(F)cc(F)c2)c1 -US07879837B2,2,COC(=O)C(N)CC=Cc1ccc(N(C)c2ncccn2)cc1.O=C(Cl)c1c(F)cccc1F>>COC(=O)C(C/C=C/c1ccc(N(C)c2ncccn2)cc1)NC(=O)c1c(F)cccc1F -US20090082379A1,1,CC1(C)NC(=O)N(c2ccc(C(C)(C)C)cc2)C1=O.ClCc1ccnc(Cl)c1>>CC(C)(C)c1ccc(N2C(=O)N(Cc3ccnc(Cl)c3)C(C)(C)C2=O)cc1 -US07368471B2,3,CC(C)(C)c1ccc(B(O)O)cc1.CC(C)(C)c1ccc(Cn2ccc3cc(Br)ccc32)cc1>>CC(C)(C)c1ccc(Cn2ccc3cc(-c4ccc(C(C)(C)C)cc4)ccc32)cc1 -US05086055,4,ClCCNCCCl.Nc1ccccc1F>>Fc1ccccc1N1CCNCC1 -US20050124692A1,6,CC(C)(C)[Si](C)(C)OCC(O)Cc1ccc2c(c1OCc1ccccc1)CCC2>>CC(C)(C)[Si](C)(C)OCC(O)Cc1ccc2c(c1O)CCC2 -US08283104B2,2,CC(C)(C)C(=O)Cl.O=S(=O)([O-])CC(O)(C(F)(F)F)C(F)(F)F>>CC(C)(C)C(=O)OC(CS(=O)(=O)[O-])(C(F)(F)F)C(F)(F)F -US20140349989A1,7,CC(C)(C)OC(=O)N1CCN(c2nn(-c3ccc([N+](=O)[O-])cc3)c3ccccc23)CC1>>CC(C)(C)OC(=O)N1CCN(c2nn(-c3ccc(N)cc3)c3ccccc23)CC1 -US08178490B2,2,CC(C)(C)OC(=O)N[C@@H](CCc1ccccc1)C(=O)O.CNCCNC(=O)c1ccc(C(F)(F)F)cc1>>CN(CCNC(=O)c1ccc(C(F)(F)F)cc1)C(=O)[C@H](CCc1ccccc1)NC(=O)OC(C)(C)C -US05723258,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(OCCC2OCCCO2)cc1>>C=Cc1ccc(OCCC2OCCCO2)cc1 -US07265246B2,7,COC(=O)c1csc(-c2ccccc2)c1>>OCc1csc(-c2ccccc2)c1 -US06124323,1,BrCCCOc1ccccc1.c1ccc(C2CCNCC2)cc1>>c1ccc(OCCCN2CCC(c3ccccc3)CC2)cc1 -US06498172B1,6,COC(=O)C(C)Cc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2ccccc2)c1>>CC(Cc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2ccccc2)c1)C(=O)O -US20040009988A1,6,Cc1cccc(C(=O)Nc2ccc(N3CCN(Cc4ccccc4)CC3)nc2)c1-c1ccc(C(C)C)cc1>>Cc1cccc(C(=O)Nc2ccc(N3CCNCC3)nc2)c1-c1ccc(C(C)C)cc1 -US20100197692A1,6,CCOC(=O)CSc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2n1C>>Cn1c(SCC(=O)O)nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc21 -US20070213364A1,3,O=Cc1cc(-c2ccc(C(F)(F)F)cc2)n[nH]1.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>FC(F)(F)c1ccc(-c2cc(/C=C/c3ccccc3)[nH]n2)cc1 -US20020151712A1,1,C(=Cc1cncc(O[C@H]2CCNC2)c1)c1ccncc1.CO>>CN1CC[C@@H](Oc2cncc(C=Cc3ccncc3)c2)C1 -US04066772,1,CC(=Cc1ccccc1)n1c(=O)[nH]c2ccc(F)cc21.ClCCCBr>>CC(=Cc1ccccc1)n1c(=O)n(CCCCl)c2ccc(F)cc21 -US20040058903A1,7,CC(C)(C)OC(=O)Nc1cccc(CCN(C(=O)OC(C)(C)C)c2ccc([N+](=O)[O-])cc2)n1>>CC(C)(C)OC(=O)Nc1cccc(CCN(C(=O)OC(C)(C)C)c2ccc(N)cc2)n1 -US08067408B2,6,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)OC)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)O)c1 -US07868171B2,6,CC(=O)Oc1ccc(C(C)ON2C(C)(C)CC3(CC2(C)C)OCC(C)(C)CO3)cc1>>CC(ON1C(C)(C)CC2(CC1(C)C)OCC(C)(C)CO2)c1ccc(O)cc1 -US05736540,7,O=C(c1ccc([N+](=O)[O-])cc1Cl)N1CCc2cccn2-c2ccccc21>>Nc1ccc(C(=O)N2CCc3cccn3-c3ccccc32)c(Cl)c1 -US20120107273A1,6,CCCc1ccc(CNC(=O)[C@H]2CN(c3nc(C)c(C(=O)OC(C)(C)C)s3)CCN2C(=O)OCc2ccccc2)cc1>>CCCc1ccc(CNC(=O)[C@H]2CN(c3nc(C)c(C(=O)OC(C)(C)C)s3)CCN2)cc1 -US20090163488A1,2,CC(C)(C#N)c1cccc(C(=O)Cl)c1.Nc1cccc(O)c1>>CC(C)(C#N)c1cccc(C(=O)Nc2cccc(O)c2)c1 -US20140378432A1,3,Cc1cc(Nc2cc(B3OC(C)(C)C(C)(C)O3)cn(C)c2=O)nn1C.O=Cc1c(Cl)ccnc1N1CCc2c(c(F)c3n2CCCC3)C1=O>>Cc1cc(Nc2cc(-c3ccnc(N4CCc5c(c(F)c6n5CCCC6)C4=O)c3C=O)cn(C)c2=O)nn1C -US20070208015A1,7,COC(=O)c1sc([N+](=O)[O-])c(C)c1Cl>>COC(=O)c1sc(N)c(C)c1Cl -US20150225404A1,1,CI.OCc1ncc(-c2cc(OCc3ccccn3)nc3c2CCCC3)s1>>COCc1ncc(-c2cc(OCc3ccccn3)nc3c2CCCC3)s1 -US20060019958A1,4,CC(C)(C)C(=O)C(Br)C#N.NC(N)=S>>CC(C)(C)c1nc(N)sc1C#N -US20140073782A1,2,CN(C)C(=O)c1ccc(NC(=O)OCC(Cl)(Cl)Cl)cc1.Nc1ccc(Br)c(F)c1F>>CN(C)C(=O)c1ccc(NC(=O)Nc2ccc(Br)c(F)c2F)cc1 -US20150210640A1,1,ClCc1ccccc1.O=C(O)[C@@H]1CC[C@@H](CO)CC1>>O=C(OCc1ccccc1)[C@@H]1CC[C@@H](CO)CC1 -US20120157432A1,6,CC(C)(C)OC(=O)N1CCC(Cn2cccn2)CC1>>c1cnn(CC2CCNCC2)c1 -US06627651B1,1,COC(=O)C1=Cc2cc(O)ccc2CCC1.OC1CCCCC1>>COC(=O)C1=Cc2cc(OC3CCCCC3)ccc2CCC1 -US04038391,2,CN1CCN(C(=O)Cl)CC1.O=C1c2ccccc2C(O)N1c1ccc2ncccc2n1>>CN1CCN(C(=O)OC2c3ccccc3C(=O)N2c2ccc3ncccc3n2)CC1 -US20100041722A1,9,NO.O=Cc1cncn1C1Cc2ccccc2C1>>ON=Cc1cncn1C1Cc2ccccc2C1 -US05811435,1,COc1cc(C(C)=O)ccc1OCCCCl.c1ccc2c(C3CCNCC3)n[nH]c2c1>>COc1cc(C(C)=O)ccc1OCCCN1CCC(c2n[nH]c3ccccc23)CC1 -US07820704B2,6,CC(C)c1ccc(-c2csc(NS(=O)(=O)CC(=O)OC(C)(C)C)n2)cc1>>CC(C)c1ccc(-c2csc(NS(=O)(=O)CC(=O)O)n2)cc1 -US20050203064A1,1,O=S(=O)(c1ccc(C=Cc2nc(CCl)co2)cc1)C(F)(F)F.O=S(CCn1ccnn1)Cc1ccc(O)cc1>>O=S(CCn1ccnn1)Cc1ccc(OCc2coc(/C=C/c3ccc(S(=O)(=O)C(F)(F)F)cc3)n2)cc1 -US04230872,7,Cc1sc(C=O)c(C)c1C>>Cc1sc(CO)c(C)c1C -US20060211863A1,3,CN(C)C=O.Cc1cc(C(=O)O)cc(C)c1Br>>Cc1cc(C(=O)O)cc(C)c1C=O -US20080255111A1,7,CCOC(=O)c1cc2ccc(F)cc2n1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1c(CO)cc2ccc(F)cc21 -US07169789B2,1,COc1cc2nccc(Cl)c2cc1OC.Nc1ccc(O)cc1[N+](=O)[O-]>>COc1cc2nccc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC -US20130281438A1,2,CN.Nc1c(C(=O)O)ccc2c1OCO2>>CNC(=O)c1ccc2c(c1N)OCO2 -US06943184B2,6,CN(C)[C@@H]1C[C@H]1COCc1ccccc1>>CN(C)[C@@H]1C[C@H]1CO -US20130345199A1,7,CC(C)CN(C)C(=O)C1CCN(Cc2cccc([N+](=O)[O-])c2)CC1>>CC(C)CN(C)C(=O)C1CCN(Cc2cccc(N)c2)CC1 -USRE041439E1,3,Brc1cncc(Br)c1.OB(O)c1ccsc1>>Brc1cncc(-c2ccsc2)c1 -US20030220368A1,3,CCCC[Sn](CCCC)(CCCC)c1nccs1.COc1ncccc1CN1CCC(CC(=O)c2sccc2Br)CC1>>COc1ncccc1CN1CCC(CC(=O)c2sccc2-c2nccs2)CC1 -US08809538B2,2,CCOc1nc(C(=O)O)cc(N)c1C#N.NCC1CCN(S(=O)(=O)c2ccc(-c3ccccn3)s2)CC1>>CCOc1nc(C(=O)NCC2CCN(S(=O)(=O)c3ccc(-c4ccccn4)s3)CC2)cc(N)c1C#N -US20100121048A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2cnn(-c3ccccc3OCc3ccccc3)c2-c2ccc(F)cc2)C(Cc2ccccc2)C1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cnn(-c3ccccc3O)c2-c2ccc(F)cc2)C(Cc2ccccc2)C1 -US07897605B2,1,C1COCCN1.Cc1nc(NC(=O)CCBr)sc1-c1ccnc(Nc2ccc(F)cc2)n1>>Cc1nc(NC(=O)CCN2CCOCC2)sc1-c1ccnc(Nc2ccc(F)cc2)n1 -US05173510,8,CCCCCCCC/C=C\CCCCCCCC(O)CCCNC(=O)CCNC(C)=O>>CCCCCCCC/C=C\CCCCCCCC(=O)CCCNC(=O)CCNC(C)=O -US20080103188A1,6,COC(=O)Cc1ccc(C#N)c2ccccc12>>N#Cc1ccc(CC(=O)O)c2ccccc12 -US20110200549A1,1,BrCC1CC1.CCCCCNC=O>>CCCCCN(C=O)CC1CC1 -US20120270838A1,6,C=CCO[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1O>>C=CCO[C@H]1CNC[C@@H]1O -US20130310333A1,2,CC(C)(C)c1ccc(N)c(N)c1.CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C(=O)CCCC(=O)O>>CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C(=O)CCCC(=O)Nc1ccc(C(C)(C)C)cc1N -US20060106084A1,1,BrC1CCCC1.O=C(c1ccc(OCc2ccccc2)cc1)c1n[nH]c2c(C(F)(F)F)cccc12>>O=C(c1ccc(OCc2ccccc2)cc1)c1nn(C2CCCC2)c2c(C(F)(F)F)cccc12 -US20090325947A1,2,COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)C[C@@H](OCC(=O)O)[C@@H]3c3ccc(OCCCOc4ccccc4Cl)cc3)cc21.NCCO>>COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)C[C@@H](OCC(=O)NCCO)[C@@H]3c3ccc(OCCCOc4ccccc4Cl)cc3)cc21 -US08334292B1,2,CS(=O)(=O)Cl.C[C@H]1CC[C@@H](Nc2ncc(-c3ccc(N4CCOCC4)cc3)c(OCC3CCNCC3)n2)CC1>>C[C@H]1CC[C@@H](Nc2ncc(-c3ccc(N4CCOCC4)cc3)c(OCC3CCN(S(C)(=O)=O)CC3)n2)CC1 -US07705030B2,3,C#Cc1cccc(Br)c1.O=Cc1cc(I)c[nH]1>>O=Cc1cc(C#Cc2cccc(Br)c2)c[nH]1 -US20050239872A1,7,CC(C)OC(=O)CCCCCCN1C(=O)CC[C@@H]1/C=C/[C@@H](O)C(F)(F)c1ccccc1>>CC(C)OC(=O)CCCCCCN1C(=O)CC[C@@H]1CC[C@@H](O)C(F)(F)c1ccccc1 -US20140303164A1,6,CSc1ncc(-c2cccc3c(N)nn(C)c23)c([C@H](Cc2cc(F)cc(F)c2)NC(=O)OC(C)(C)C)n1>>CSc1ncc(-c2cccc3c(N)nn(C)c23)c([C@@H](N)Cc2cc(F)cc(F)c2)n1 -US04299767,7,CC(=O)OCCNC(=O)Nc1ccc2c(c1)C(c1ccccc1F)=NCC(=O)N2C>>CN1C(=O)CN=C(c2ccccc2F)c2cc(NC(=O)NCCO)ccc21 -US06727264B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Cl>>Cc1onc(-c2c(F)cccc2Cl)c1C(=O)N[C@@H](CCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)c1ccccc1 -US08993586B2,8,CCOC(=O)c1ccc2ncccc2c1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1ccc2c(ccc[n+]2[O-])c1 -US20060040949A1,6,COc1ccc2nccc(OCC3CCC(NC(=O)OC(C)(C)C)CC3)c2c1>>COc1ccc2nccc(OC[C@@H]3CC[C@@H](N)CC3)c2c1 -US05840917,5,CC(=O)c1ccsc1.OCCO>>CC1(c2ccsc2)OCCO1 -US06320051B1,7,O=c1cc(NCCC2CC=CCN2Cc2ccc(Cl)c(Cl)c2)[nH]c2ccccc12>>O=c1cc(NCCC2CCCCN2Cc2ccc(Cl)c(Cl)c2)[nH]c2ccccc12 -US20120101083A1,3,CC(C)Oc1ccc(-c2nnc(Br)s2)cc1C#N.Cc1c(B2OC(C)(C)C(C)(C)O2)ccc2c1CCN(C(=O)OC(C)(C)C)C2>>Cc1c(-c2nnc(-c3ccc(OC(C)C)c(C#N)c3)s2)ccc2c1CCN(C(=O)OC(C)(C)C)C2 -US09051323B2,1,CC(=O)c1ccc(Cl)nc1NC(=O)OC(C)(C)C.NCCNc1nc(-c2ccc(Cl)cc2Cl)cc2nccn12>>CC(=O)c1ccc(NCCNc2nc(-c3ccc(Cl)cc3Cl)cc3nccn23)nc1NC(=O)OC(C)(C)C -US05866589,1,CC=O.CCCN(c1ncccc1N)C1CCN(Cc2ccccc2)CC1>>CCCN(c1ncccc1NCC)C1CCN(Cc2ccccc2)CC1 -US20090163586A1,3,C#CC(C)(C)C.NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccc(Br)cc1>>CC(C)(C)C#Cc1ccc(CCS(=O)(=O)Nc2ccccc2S(N)(=O)=O)cc1 -US04705850,3,C=C/C=C/C[C@H]1C[C@H](NC(=O)C(F)(F)F)[C@H](OC(=O)c2ccc([N+](=O)[O-])cc2)[C@H](C)O1.O=C1C=CC(=O)c2ccccc21>>C[C@@H]1O[C@@H](CC2C=CCC3C(=O)c4ccccc4C(=O)C23)C[C@H](NC(=O)C(F)(F)F)[C@@H]1OC(=O)c1ccc([N+](=O)[O-])cc1 -US04341784,1,C1CCNC1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)nc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCCC3)nc21 -US20050282858A1,7,O=C(O)[C@H]1NCC[C@@H]1c1ccccc1>>OC[C@H]1NCC[C@@H]1c1ccccc1 -US04198522,2,CC(=O)Br>>Br -US04198522,2,CC(=O)Br.CCCCCCCCCCCCCCCCNc1ccc(CO)cc1>>CCCCCCCCCCCCCCCCNc1ccc(COC(C)=O)cc1 -US20120101082A1,1,BrCc1ccccc1.Cc1nc2c([nH]1)-c1ccccc1N(C(=O)c1ccccc1)CC2>>Cc1nc2c(n1Cc1ccccc1)-c1ccccc1N(C(=O)c1ccccc1)CC2 -US08084448B2,3,C=CC(=O)NC(C)C.C[Si](C)(C)CCN1C(=O)CN(c2ccc(I)cc2OCc2ccccc2)S1(=O)=O>>CC(C)NC(=O)/C=C/c1ccc(N2CC(=O)N(CC[Si](C)(C)C)S2(=O)=O)c(OCc2ccccc2)c1 -US20130079328A1,1,CC(C)(C)OC(=O)NCc1cc[nH]c(=O)c1.FC(F)(F)c1cc(Br)ccn1>>CC(C)(C)OC(=O)NCc1ccn(-c2ccnc(C(F)(F)F)c2)c(=O)c1 -US20080227781A1,2,CC(C)[C@H](O)C(=O)O.CCCC(N)C(=O)Nc1cn(C(C)(C)CC(=O)OC)cn1>>CCCC(NC(=O)C(O)C(C)C)C(=O)Nc1cn(C(C)(C)CC(=O)OC)cn1 -US20090209522A1,1,COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Br)n1.Cc1ccc(OCC(C)C)cc1O>>COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Oc2cc(OCC(C)C)ccc2C)n1 -US20090274733A1,2,CC(=O)OC(C)=O.NCC[C@@H]1CCc2ccc3c(c21)CCO3>>CC(=O)NCC[C@@H]1CCc2ccc3c(c21)CCO3 -US07427613B2,1,COc1ccc(F)c(C=O)c1.NC1CC1>>COc1ccc(F)c(CNC2CC2)c1 -US20070254872A1,2,COc1ccc2nccc(CCN3CCOC(CN)C3)c2n1.O=C1CSc2ccc(C(=O)O)nc2N1>>COc1ccc2nccc(CCN3CCOC(CNC(=O)c4ccc5c(n4)NC(=O)CS5)C3)c2n1 -US20100210641A1,3,Clc1ccn2c(Br)cnc2c1.OB(O)c1ccnc(Cl)c1>>Clc1ccn2c(-c3ccnc(Cl)c3)cnc2c1 -US20100048570A1,2,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCSC1C(=O)O)Cc1cc(F)c(F)cc1F.CCOC(=O)C(Oc1ccc(CN)cc1)C(C)C>>CCOC(=O)C(Oc1ccc(CNC(=O)C2SCCN2C(=O)C[C@@H](Cc2cc(F)c(F)cc2F)NC(=O)OC(C)(C)C)cc1)C(C)C -US05053073,3,O=Cc1ccoc1.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>C(=C/c1ccoc1)\c1ccccc1 -US06627651B1,2,CN(CCN1CCC(N)CC1)C1CCOCC1.Cc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCO3)cc1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)NC2CCN(CCN(C)C4CCOCC4)CC2)CCO3)cc1 -US07732446B1,6,COc1cc2c(CC(=O)N3CCC(Cc4ccccc4)CC3)cnc(CNC(=O)OC(C)(C)C)c2cc1OC>>COc1cc2c(CC(=O)N3CCC(Cc4ccccc4)CC3)cnc(CN)c2cc1OC -US20150148327A1,1,COCCN.Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cncc(Br)c2)c1>>COCCNc1cncc(-c2cc(C)cc(Nc3nccc(C(F)(F)F)n3)c2)c1 -US20030119807A1,2,C1CCNC1.CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)N2CCCC2)no1 -US20140155391A1,7,COC(=O)c1ccc([N+](=O)[O-])cc1OCC1CC1>>COC(=O)c1ccc(N)cc1OCC1CC1 -US20060154960A1,6,COC(=O)c1ccc(Cn2nccc2-c2ccc(OC)c(O[C@@H]3CCOC3)c2)cc1>>COc1ccc(-c2ccnn2Cc2ccc(C(=O)O)cc2)cc1O[C@@H]1CCOC1 -US20100311966A1,6,CCCCOC(=O)c1nc(N2CC[C@H](NC(=O)OCc3ccccc3)[C@H](OCCC)C2)oc1CC>>CCCCOC(=O)c1nc(N2CC[C@H](N)[C@H](OCCC)C2)oc1CC -US20080076771A1,1,CNCCOC.Clc1cc(Cl)ncn1>>COCCN(C)c1cc(Cl)ncn1 -US20100041892A1,2,COCCOc1ccc(CCC(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1.NS(N)(=O)=O>>COCCOc1ccc(CCC(=O)NS(N)(=O)=O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1 -US20090286778A1,7,CC(C)(C)OC(=O)Nc1cccc(NS(=O)(=O)Cc2cccc([N+](=O)[O-])c2)c1>>CC(C)(C)OC(=O)Nc1cccc(NS(=O)(=O)Cc2cccc(N)c2)c1 -US08329913B2,1,COc1cc(CCl)ccc1OCc1nc(-c2ccco2)oc1C.O=C(O)C(Oc1cccc2[nH]c3ccccc3c12)c1ccccc1>>COc1cc(Cn2c3ccccc3c3c(OC(C(=O)O)c4ccccc4)cccc32)ccc1OCc1nc(-c2ccco2)oc1C -US20050152858A1,2,CC(O)c1ccccc1.O=C(Cl)c1ccccc1>>CC(OC(=O)c1ccccc1)c1ccccc1 -US20100004238A1,1,Cn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2ccc3c(c2)CNC3=O)c(Cl)c1>>Cn1ccc2ncnc(Nc3ccc(Oc4ccc5c(c4)CNC5=O)c(Cl)c3)c21 -US04387230,1,C=O.O[C@@H]1CNC[C@H](c2ccc(C(F)(F)F)cc2)C1>>CN1C[C@H](c2ccc(C(F)(F)F)cc2)C[C@H](O)C1 -US08637500B2,7,C1=COC(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)C1>>c1ccc(Nc2ccc(Oc3ncccc3C3CCCO3)cc2)nc1 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)CC2CC2)CN1C(=O)C1(C)CC1>>CC1(C(=O)N2C[C@H](S(=O)(=O)CC3CC3)C[C@H]2C(=O)O)CC1 -US20090181966A1,6,CCOC(=O)CNCCCOc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)C[C@@H]2C)cc1>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCCNCC(=O)O)cc2)c2ccccc21 -US04160837,7,Cc1ccc(OC2CCN(C(=O)OCc3ccccc3)CC2=O)cc1C>>Cc1ccc(O[C@H]2CCN(C(=O)OCc3ccccc3)C[C@H]2O)cc1C -US20050131014A1,1,CCNCC.O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(OCc2ccc(CCl)cc2)c1>>CCN(CC)Cc1ccc(COc2cccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1 -US20030105074A1,7,Cc1ccc(C#N)cc1Cl>>Cc1ccc(CN)cc1Cl -US20050288293A1,6,CCOC(=O)c1cn2c(c1O)C(=O)N(Cc1ccc(F)cc1)CC2>>O=C(O)c1cn2c(c1O)C(=O)N(Cc1ccc(F)cc1)CC2 -US20150133402A1,2,NCCOCc1ccccc1.O=C(O)COc1cccc2c1B(O)OC2>>O=C(COc1cccc2c1B(O)OC2)NCCOCc1ccccc1 -US20070269664A1,7,CCCCOc1ccc(CC(=O)OCC)cc1Cl>>CCCCOc1ccc(CCO)cc1Cl -US20150051197A1,1,N#Cc1cc(Cl)ccc1F.O=S1(=O)CCN2C(=N1)C1(c3ccc(O)cc3)CCC2CC1>>N#Cc1cc(Cl)ccc1Oc1ccc(C23CCC(CC2)N2CCS(=O)(=O)N=C23)cc1 -US07229987B2,3,BrCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COC(=O)c1ccc(C=O)cc1>>COC(=O)c1ccc(C=CCCCBr)cc1 -US08053581B2,1,C1COCCN1.COc1ccc(-c2nc(Cl)sc2Cc2ccccc2)cc1>>COc1ccc(-c2nc(N3CCOCC3)sc2Cc2ccccc2)cc1 -US06982348B2,2,NC(Cc1ccc(F)cc1)C(O)c1ccc(C(F)(F)F)cc1.O=C(O)c1ccc(F)c2ccccc12>>O=C(NC(Cc1ccc(F)cc1)C(O)c1ccc(C(F)(F)F)cc1)c1ccc(F)c2ccccc12 -US20140066426A1,1,CN(CC(C)(C)C)C(=O)c1[nH]c(C(F)(F)F)cc1-c1ccc(Cl)cc1.Fc1ccc(CBr)cc1>>CN(CC(C)(C)C)C(=O)c1c(-c2ccc(Cl)cc2)cc(C(F)(F)F)n1Cc1ccc(F)cc1 -US07312225B2,7,O=[N+]([O-])c1ccccc1OCCCNc1nc(Cl)ncc1Br>>Nc1ccccc1OCCCNc1nc(Cl)ncc1Br -US05798311,3,C=O.CCCOC(C)C(=O)c1ccc(Cl)cc1>>CCCOC(C)(CO)C(=O)c1ccc(Cl)cc1 -US07345067B2,6,CCOC(=O)COc1ccc(N(C)Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C>>Cc1cc(N(C)Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O -US20070244103A1,6,COc1cnc2ccc(Cl)c(C(O)CN3C4CCC3CC(NC(=O)OC(C)(C)C)C4)c2n1>>COc1cnc2ccc(Cl)c(C(O)CN3C4CCC3CC(N)C4)c2n1 -US08048893B2,6,CCN(CC)CCn1cc(-c2ccccc2)c(OCc2ccccc2)n1>>CCN(CC)CCn1cc(-c2ccccc2)c(O)n1 -US20120232033A1,3,Brc1ccc(OC2CCOCC2)nc1.CON(C)C(=O)C(NC(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)NC(C(=O)c1ccc(OC2CCOCC2)nc1)c1ccc(Cl)c(Cl)c1 -US06683215B2,3,CCOc1cc(OS(=O)(=O)C(F)(F)F)cc(C(Nc2ccc(C#N)cc2)C(=O)OC)c1.Nc1cccc(B(O)O)c1>>CCOc1cc(-c2cccc(N)c2)cc(C(Nc2ccc(C#N)cc2)C(=O)OC)c1 -US20080125413A1,2,NNc1ccccc1.O=C(O)Cc1ccncc1>>O=C(Cc1ccncc1)NNc1ccccc1 -US20150057260A1,3,C#C[C@]1(O)CCN(C)C1=O.CCNc1ccc(-c2ccc(C#N)c(Cl)c2)nc1C(N)=O>>CCNc1ccc(-c2ccc(C#N)c(C#C[C@]3(O)CCN(C)C3=O)c2)nc1C(N)=O -US20080167330A1,7,CS(C)(=O)=NC(=O)Nc1cc([N+](=O)[O-])ccc1Cl>>CS(C)(=O)=NC(=O)Nc1cc(N)ccc1Cl -US07179934B2,4,CC(=O)OO.CC(C)=CCC[C@H](C)CCC1CCCCC1>>C[C@H](CCC1CCCCC1)CCC1OC1(C)C -US20080004274A1,1,CCCCCN1C(=O)C(=O)c2cc(SCCc3ccc(C(=O)O)cc3)ccc21.NNC(=S)NCc1ccccc1>>CCCCCN1C(=O)C(=NNC(=S)NCc2ccccc2)c2cc(SCCc3ccc(C(=O)O)cc3)ccc21 -US20040209921A1,6,CC(=O)OCc1ncccc1S(=O)c1ccccc1>>O=S(c1ccccc1)c1cccnc1CO -US04623648,1,O=C(O)c1cccnc1Cl.[O-]c1ccccc1>>O=C(O)c1cccnc1Oc1ccccc1 -US08269008B2,10,CCOC(=O)c1c(-c2ccccc2)noc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1c(-c2ccccc2)noc1CBr -US20120190677A1,2,CN(C)c1cccc(C2CC(C)(C)c3cc(Cl)cc(C(=O)O)c3N2)c1.NS(=O)(=O)C1CC1>>CN(C)c1cccc(C2CC(C)(C)c3cc(Cl)cc(C(=O)NS(=O)(=O)C4CC4)c3N2)c1 -US07803833B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NCCC[C@]12CCC(c1ccc(O)cc1)N2>>CC(C)(C)OC(=O)N1C(c2ccc(O)cc2)CC[C@]12CCCNC2=O -US20130072523A1,6,C[C@H]1C[C@@H](c2ncc(I)[nH]2)N(C(=O)OC(C)(C)C)C1>>C[C@@H]1CN[C@H](c2ncc(I)[nH]2)C1 -US04374835,1,Cn1c(=O)c2c(ncn2CCCCl)n(C)c1=O.c1ccc(SCCCN2CCNCC2)cc1>>Cn1c(=O)c2c(ncn2CCCN2CCN(CCCSc3ccccc3)CC2)n(C)c1=O -US20090215822A1,2,O=C(Cl)c1ccc(F)cc1.c1ccc(-c2nc(C3CCCNC3)no2)cc1>>O=C(c1ccc(F)cc1)N1CCCC(c2noc(-c3ccccc3)n2)C1 -US07271262B2,1,CC=O.Nc1ncnc2c1c(C(=O)c1cccc(NC(=O)Nc3cc(Cl)cc(Cl)c3)c1)cn2C1CCNCC1>>CCN1CCC(n2cc(C(=O)c3cccc(NC(=O)Nc4cc(Cl)cc(Cl)c4)c3)c3c(N)ncnc32)CC1 -US20100240636A1,1,CCOC(=O)C(C)(Cc1ccc(Oc2cc(Cl)nc(NCc3ccccc3)n2)cc1)Oc1ccccc1.c1ccc(CN2CCNCC2)cc1>>CCOC(=O)C(C)(Cc1ccc(Oc2cc(N3CCN(Cc4ccccc4)CC3)nc(NCc3ccccc3)n2)cc1)Oc1ccccc1 -US20120214803A1,1,Nc1ccccc1.O=[N+]([O-])c1c(Cl)ccc2cccnc12>>O=[N+]([O-])c1c(Nc2ccccc2)ccc2cccnc12 -US05489693,2,COC(=O)CCc1ccc(C2=C(OC)CN(c3ccc(C(=N)N)cc3)C2=O)cc1.COC(=O)Cl>>COC(=O)CCc1ccc(C2=C(OC)CN(c3ccc(C(=N)NC(=O)OC)cc3)C2=O)cc1 -US08367702B2,2,CCCCCCS(=O)(=O)Cl.Cc1c(CN)[nH]c2ccccc2c1=O>>CCCCCCS(=O)(=O)NCc1[nH]c2ccccc2c(=O)c1C -US20090054435A1,1,COc1ccc(C(=O)c2ccc(Cl)nc2)c(OC(C)(C)C(=O)OC(C)(C)C)c1.OCCc1ccccc1>>COc1ccc(C(=O)c2ccc(OCCc3ccccc3)nc2)c(OC(C)(C)C(=O)OC(C)(C)C)c1 -US20140171407A1,4,CC#Cc1cc(Cl)cnc1N>>Cc1cc2cc(Cl)cnc2[nH]1 -US06984653B2,1,CS(=O)(=O)Cc1nccn1CCCCc1ccc(O)cc1.Fc1ccc(/C=C/c2nc(CCl)co2)c(F)c1>>CS(=O)(=O)Cc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3ccc(F)cc3F)n2)cc1 -US20150030704A1,3,Clc1cc(OCc2ccccc2)c(OCc2ccccc2)nn1.FC(F)(F)c1cc(CCl)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(Cc2cc(OCc3ccccc3)c(OCc3ccccc3)nn2)cc(C(F)(F)F)c1 -US04321372,6,CC1(C)CCc2nc(NC(=O)C(=O)OCc3ccccc3)sc2C1>>CC1(C)CCc2nc(NC(=O)C(=O)O)sc2C1 -US20040157866A1,2,Cc1ccc(-c2ccccc2C(=O)Nc2ccc3c(c2)CCN3)cc1.Cc1ccc(C)n1-c1nccc(CC(=O)O)n1>>Cc1ccc(-c2ccccc2C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2ccnc(-n3c(C)ccc3C)n2)cc1 -US20070254869A1,2,CC(=O)OC(C)=O.CC(C)OC(=O)N1CCCC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccc3c(c21)CCC3>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2c1ccc1c2CCC1 -US20090099195A1,1,CC(C)N1Cc2c(NCc3cc4ccccc4cn3)nc(Cl)nc2C1=O.C[C@H]1CNCCN1C(=O)OC(C)(C)C>>CC(C)N1Cc2c(NCc3cc4ccccc4cn3)nc(N3CCN(C(=O)OC(C)(C)C)[C@@H](C)C3)nc2C1=O -US03969368,7,CCOC(=O)CC1(C)Oc2ccc([N+](=O)[O-])cc2O1>>CCOC(=O)CC1(C)Oc2ccc(N)cc2O1 -US20100292279A1,3,C#CC(C)C.COC(=O)c1ccc(Br)c(OC(C)C)c1>>COC(=O)c1ccc(C#CC(C)C)c(OC(C)C)c1 -US05948911,1,COC(=O)c1ccc(-c2nc(Cl)c3c(C)c(C)sc3n2)cc1.NCCc1ccccc1>>COC(=O)c1ccc(-c2nc(NCCc3ccccc3)c3c(C)c(C)sc3n2)cc1 -US05034411,1,CCCSCCCBr.CCNCC(O)c1ccc(C#N)cc1>>CCCSCCCN(CC)CC(O)c1ccc(C#N)cc1 -US05753664,1,Cn1ncc2[nH]ccc2c1=O.O=C(c1ccc(CBr)cc1)c1ccc(Cl)cc1Cl>>Cn1ncc2c(ccn2Cc2ccc(C(=O)c3ccc(Cl)cc3Cl)cc2)c1=O -US20100331293A1,2,CS(=O)(=O)Cl.Cc1c(N2CCN[C@@H](C)C2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1>>Cc1c(N2CCN(S(C)(=O)=O)[C@@H](C)C2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1 -US20100137305A1,1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.CC(C)=O>>CC(C)=N[C@@H]1CCN(C(=O)OC(C)(C)C)C1 -US20040158074A1,3,Brc1cc2c(cc1Br)OCO2.OB(O)c1ccc(F)cc1>>Fc1ccc(-c2cc3c(cc2Br)OCO3)cc1 -US20020082258A1,2,CN1CC(CO)Oc2ccccc21.CS(=O)(=O)Cl>>CN1CC(COS(C)(=O)=O)Oc2ccccc21 -US20020183285A1,6,CCOC(=O)c1ccc(C#Cc2ccc(C3(OCC)CC3)c(C(C)(C)C)c2)cc1>>CCOC1(c2ccc(C#Cc3ccc(C(=O)O)cc3)cc2C(C)(C)C)CC1 -US07696240B2,1,CCOC(=O)c1[nH]c2ccccc2c1Cc1cccc2ccccc12.CN(C)C(=O)CCl>>CCOC(=O)c1c(Cc2cccc3ccccc23)c2ccccc2n1CC(=O)N(C)C -US08106212B2,7,O=C(O)c1cnc(Cl)c(Cl)c1>>OCc1cnc(Cl)c(Cl)c1 -US20080255085A1,4,COC(=O)c1cccc(C(=O)O)c1.Nc1cccnc1N>>COC(=O)c1cccc(-c2nc3cccnc3[nH]2)c1 -US04542132,7,CC(O)(CO)c1ccncc1>>CC(O)(CO)C1CCNCC1 -US20080176862A1,7,CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2ccc(F)c(/C=C/C3CC3)c2)N=C1N>>CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2ccc(F)c(CCC3CC3)c2)N=C1N -US04119710,6,CC(=O)Nc1ccc(C(O)CNC(C)(C)C)cc1C(F)(F)F>>CC(C)(C)NCC(O)c1ccc(N)c(C(F)(F)F)c1 -US20060167247A1,6,COC(=O)c1ccc2c(c1Cl)OCO2>>O=C(O)c1ccc2c(c1Cl)OCO2 -US20140023611A1,1,CCOC(=O)CNC(=O)CCS.O=C(Nc1ccc(N2CCCCC2)cc1C(=O)N/N=C/c1ccc(Cl)c(C(F)(F)F)c1)c1cccc(CBr)c1>>CCOC(=O)CNC(=O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)c1 -US04780504,1,Nc1ccc(C(=O)O)cc1.O=Cc1cc(Cl)ccc1O>>O=C(O)c1ccc(N=Cc2cc(Cl)ccc2O)cc1 -US20110288066A1,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)N(C)C(C)C)cc1Br>>Cc1ccc(S(=O)(=O)N(C)C(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C -US20010039351A1,2,O=C(Cl)c1ccccc1.O=S(=O)(CCO)CCCOCCc1ccccc1>>O=C(OCCS(=O)(=O)CCCOCCc1ccccc1)c1ccccc1 -US20100305118A1,7,CN(C)CCc1cccc(Nc2nccc(-c3c(-c4ccc(N)c([N+](=O)[O-])c4)nc4ccccn34)n2)c1>>CN(C)CCc1cccc(Nc2nccc(-c3c(-c4ccc(N)c(N)c4)nc4ccccn34)n2)c1 -US04673746,4,COc1ccc(/C(=N\OC(C)=O)c2cccc(F)c2F)c(O)c1Cl>>COc1ccc2c(-c3cccc(F)c3F)noc2c1Cl -US04129737,1,CCOC(=O)c1cn(CC)c2nc(Cl)ncc2c1=O.OCCN1CCNCC1>>CCOC(=O)c1cn(CC)c2nc(N3CCN(CCO)CC3)ncc2c1=O -US20150166564A1,7,Cc1c(N=O)c(-c2ccccc2)nn1CC(F)(F)F>>Cc1c(N)c(-c2ccccc2)nn1CC(F)(F)F -US20150018343A1,1,COC(=O)C(C)Br.O=Cc1ccccc1O>>COC(=O)C(C)Oc1ccccc1C=O -US06677341B2,1,Cc1cc(O)ccc1F.O[C@H](CN(Cc1cccc(OC(F)(F)F)c1)c1cccc(Br)c1)C(F)(F)F>>Cc1cc(Oc2cccc(N(Cc3cccc(OC(F)(F)F)c3)C[C@@H](O)C(F)(F)F)c2)ccc1F -US20090062282A1,1,BrCC1OCCO1.Nc1nc(CCc2ccc3cc[nH]c3c2)cc(=O)[nH]1>>Nc1nc(CCc2ccc3cc[nH]c3c2)cc(=O)n1CC1OCCO1 -US04057418,1,Nc1cc(Cl)cc(C(=O)O)c1Cl.O=S(=O)(CO)CCCl>>O=C(O)c1cc(Cl)cc(NCS(=O)(=O)CCCl)c1Cl -US07820865B2,1,CCC(C)(C)c1cc(C(=O)CBr)cc(C(C)(C)CC)c1O.COc1cc(C=O)ccc1O>>CCC(C)(C)c1cc(C(=O)COc2ccc(C=O)cc2OC)cc(C(C)(C)CC)c1O -US20030018056A1,1,CCOC(=O)c1cc2c(C)c(OCc3ccccc3)ccc2[nH]1.CI>>CCOC(=O)c1cc2c(C)c(OCc3ccccc3)ccc2n1C -US20090156571A1,1,CI.O=C1[C@H](Cc2c(Cl)cc(OCc3ccccc3)cc2Cl)CCN1[C@@H]1CC[C@@H](O)CC1>>CO[C@@H]1CC[C@@H](N2CC[C@@H](Cc3c(Cl)cc(OCc4ccccc4)cc3Cl)C2=O)CC1 -US06355662B1,6,COC(=O)CCc1cnc(C2CCCN2C(=O)OC(C)(C)C)s1>>COC(=O)CCc1cnc(C2CCCN2)s1 -US20070225271A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.Nc1nc(Cl)nc2cc3c(cc12)OCO3>>CC(C)(C)OC(=O)N1CCC(Nc2nc(N)c3cc4c(cc3n2)OCO4)CC1 -US20090291942A1,6,CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CCO[Si](C)(C)C(C)(C)C)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CCO)cc1 -US08546588B2,5,O=Cc1nccs1.OCCO>>c1csc(C2OCCO2)n1 -US05719141,3,CC(C)(C)OC(=O)N1[C@@H](CC2(C=O)CC2)COC1(C)C.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=CC1(C[C@H]2COC(C)(C)N2C(=O)OC(C)(C)C)CC1 -US20100041891A1,6,CCOC(=O)c1cccc(-c2cccc3c(C)c(Cc4ccc(F)c(Cl)c4)sc23)c1>>Cc1c(Cc2ccc(F)c(Cl)c2)sc2c(-c3cccc(C(=O)O)c3)cccc12 -US07718670B2,1,BrCCCOc1ccccc1.O=C(N[C@H]1CN2CCC1CC2)C1c2ccccc2Oc2ccccc21>>O=C(N[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)C1c2ccccc2Oc2ccccc21 -US20130172556A1,1,CC(=O)CS(C)(=O)=O.NN>>CC(CS(C)(=O)=O)=NN -US07157463B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CC1NCCc2ccccc21>>COC(=O)CC1c2ccccc2CCN1C(=O)OC(C)(C)C -US20060178410A1,7,COc1ccc([N+](=O)[O-])cc1-c1cccc(Cl)c1>>COc1ccc(N)cc1-c1cccc(Cl)c1 -US20130090323A1,1,C1COCCN1.CC(C)Oc1ccc(-c2cnc(Cl)cc2N)cc1F>>CC(C)Oc1ccc(-c2cnc(N3CCOCC3)cc2N)cc1F -US08030354B2,6,COc1ccc(F)c(-c2ccc(CO[Si](C)(C)C(C)(C)C)cc2C(O)C2(C)CC2)c1>>COc1ccc(F)c(-c2ccc(CO)cc2C(O)C2(C)CC2)c1 -US07230098B2,3,CC1(C)OB(c2ccc(OCCN3CCOCC3)cc2)OC1(C)C.Nc1ncc(Br)cc1OCc1c(Cl)cccc1Cl>>Nc1ncc(-c2ccc(OCCN3CCOCC3)cc2)cc1OCc1c(Cl)cccc1Cl -US04985448,6,CC(=O)Nc1ccc2c(c1)NC(=O)CC2(C)C>>CC1(C)CC(=O)Nc2cc(N)ccc21 -US20140356322A1,1,CCOC(=O)C(Br)C(C)C.O=C1NCc2cccc(Cl)c21>>CCOC(=O)C(C(C)C)N1Cc2cccc(Cl)c2C1=O -US20050107449A1,1,CC(C)c1nc(-c2ccc(C(F)(F)F)cc2)oc1C(C)CO.COC(=O)Cc1cccc(O)c1>>COC(=O)Cc1cccc(OCC(C)c2oc(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)c1 -US20140213448A1,1,CCN(C(=O)CCS)c1cn(-c2cccnc2)nc1Cl.FC(F)(F)C(Cl)Br>>CCN(C(=O)CCSC(Cl)C(F)(F)F)c1cn(-c2cccnc2)nc1Cl -US20050176775A1,6,COC(=O)c1ccc(C)c(-n2c(C)cc(COc3ccc(F)cc3F)c(Br)c2=O)c1>>Cc1ccc(C(=O)O)cc1-n1c(C)cc(COc2ccc(F)cc2F)c(Br)c1=O -US20110230462A1,3,C[Si](C)(C)CCOCn1cc(C=O)c2nc(Br)cnc21.Cc1nn(C)cc1B1OC(C)(C)C(C)(C)O1>>Cc1nn(C)cc1-c1cnc2c(n1)c(C=O)cn2COCC[Si](C)(C)C -US07557127B2,6,CCOC(=O)/C(F)=C/c1cnc(N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)c(Cl)c1>>CCOC(=O)/C(F)=C/c1cnc(N[C@@H]2CCNC2)c(Cl)c1 -US20100190831A1,3,CCOC(=O)C(C)=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(F)c(OCc2ccccc2)c(F)c1>>CCOC(=O)/C(C)=C/c1cc(F)c(OCc2ccccc2)c(F)c1 -US20090143352A1,3,COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(B3OC(C)(C)C(C)(C)O3)cc12.O=C(O)c1cc(I)cc(F)c1NC1CCC(O)CC1>>COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(-c3cc(F)c(NC4CCC(O)CC4)c(C(=O)O)c3)cc12 -US05439955,3,C=O.CCNCC.Cc1ccc(O)c(-n2nc3ccccc3n2)c1>>CCN(CC)Cc1cc(C)cc(-n2nc3ccccc3n2)c1O -US05958914,6,CCOC(=O)/C(=N\OC(c1ccccc1)(c1ccccc1)c1ccccc1)c1nc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)sc1C>>Cc1sc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)nc1/C(=N/OC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O -US08609848B2,2,COc1ccc(C(=O)Cl)c(OC)c1.COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OC>>COc1ccc(C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)C(C)(C)C3=O)CC2)c(OC)c1 -US20090062259A1,2,NC1CCCCC1.O=C(O)Cc1cccc(CC(=O)O)c1>>O=C(O)Cc1cccc(CC(=O)NC2CCCCC2)c1 -US08148383B2,1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)[nH]c2nc(C)nn12.OC(CBr)C(F)(F)F>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC(O)C(F)(F)F)c2nc(C)nn12 -US20140275057A1,2,Nc1ccc(S(=O)(=O)c2cccc(OC(F)(F)F)c2)cc1.O=C(Cl)C=Cc1cccnc1>>O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cccc(OC(F)(F)F)c2)cc1 -US07524873B2,2,C[C@@H](N)c1ccccc1.Cc1ccc(C(=O)Cl)cc1Br>>Cc1ccc(C(=O)N[C@H](C)c2ccccc2)cc1Br -US20130261116A1,2,C1CCN(C2CCNCC2)C1.O=C(O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1>>O=C(c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1)N1CCC(N2CCCC2)CC1 -US20060166980A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.N#Cc1ccc(NCCCO)cc1>>Cc1ccc(S(=O)(=O)OCCCNc2ccc(C#N)cc2)cc1 -US20130196974A1,1,C1COCCN1.Cc1ccc2nc(N3CCS(=O)(=O)c4ccc(F)cc4C3)cc(NCC3(N(Cc4ccccc4)Cc4ccccc4)COC3)c2c1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccc(N5CCOCC5)cc4C3)cc(NCC3(N(Cc4ccccc4)Cc4ccccc4)COC3)c2c1 -US20150252036A1,3,CC(C)(C)OC(=O)N1CCc2c(F)ccc(Br)c2C1.CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(F)c3c2CN(C(=O)OC(C)(C)C)CC3)c1 -US08410107B2,1,C[C@H](O)C(F)(F)F.Fc1ncc(Cl)cc1-c1ccc(Cl)cc1>>C[C@H](Oc1ncc(Cl)cc1-c1ccc(Cl)cc1)C(F)(F)F -US20050171350A1,6,CC(C)(C)OC(=O)N1C[C@@H](C(c2ccccc2)c2ccccc2)N2CCN(C(=O)N3CCOCC3)C[C@H]2C1>>O=C(N1CCOCC1)N1CCN2[C@H](C(c3ccccc3)c3ccccc3)CNC[C@@H]2C1 -US20100298287A1,1,CCOC(=O)CCCn1c(Cl)nc2c(Cl)ccc(C(CC)CC)c21.Nc1ccc(OC(F)(F)F)cc1Br>>CCOC(=O)CCCn1c(Nc2ccc(OC(F)(F)F)cc2Br)nc2c(Cl)ccc(C(CC)CC)c21 -US08871967B2,2,CCCCC(C)C(=O)O.OCC1CC1>>CCCCC(C)C(=O)OCC1CC1 -US20120059019A1,2,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)c(OC)cc3C)c(F)c12.NC1(c2nc3cnccc3o2)CC1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5nc6cnccc6o5)CC4)c(OC)cc3C)c(F)c12 -US07419997B2,2,NC1CCCc2c1[nH]c1ccc(Br)cc21.O=C(Cl)c1ccc(C(F)(F)F)cc1>>O=C(NC1CCCc2c1[nH]c1ccc(Br)cc21)c1ccc(C(F)(F)F)cc1 -US08143263B2,6,C[C@H](CO[Si](C)(C)C(C)(C)C)OC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(C#N)cn1>>C[C@H](CO)OC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(C#N)cn1 -US20070027163A1,1,COc1cccc(OC)c1C1CCN(C(=O)c2c[nH]c3cc(Cl)ccc23)CC1.ClCc1ccncc1>>COc1cccc(OC)c1C1CCN(C(=O)c2cn(Cc3ccncc3)c3cc(Cl)ccc23)CC1 -US07473699B2,9,[N-]=[N+]=NC[C@H]1CN(c2cc(F)c(C3=CCN(Cc4ccccc4)CC3)c(F)c2)C(=O)O1>>NC[C@H]1CN(c2cc(F)c(C3=CCN(Cc4ccccc4)CC3)c(F)c2)C(=O)O1 -US20040072818A1,1,CN(C(=O)OC(C)(C)C)C1CCNC1.Clc1ccc2c(Cl)ccnc2c1>>CN(C(=O)OC(C)(C)C)C1CCN(c2ccnc3cc(Cl)ccc23)C1 -US20040009995A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSC1=NCCN1>>CSC1=NCCN1C(=O)OC(C)(C)C -US20080293782A1,3,CC1(C)OB(c2cccc(OS(C)(=O)=O)c2)OC1(C)C.O=C1CN(c2cc(Br)ccc2OCc2ccccc2)S(=O)(=O)N1>>CS(=O)(=O)Oc1cccc(-c2ccc(OCc3ccccc3)c(N3CC(=O)NS3(=O)=O)c2)c1 -US20140018371A1,1,CC(C)(C)OC(=O)N1CCC(CO)CC1.Oc1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC(COc2ccc(OCc3ccccc3)cc2)CC1 -US04187247,3,CCOC(=O)C=C(C)C=CC=C(C)C=O.COc1c(C)c(C)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(Cl)c1C>>CCOC(=O)C=C(C)C=CC=C(C)C=Cc1c(C)c(C)c(OC)c(C)c1Cl -US04518597,7,COc1cccc([N+](=O)[O-])c1C#N>>COc1cccc(N)c1C#N -US04410529,2,Nc1ccc(C2=NNC(=O)CC2)cc1.O=C(O)C1CC1(Cl)Cl>>O=C1CCC(c2ccc(NC(=O)C3CC3(Cl)Cl)cc2)=NN1 -US20080269213A1,1,BrCc1ccccc1.C=CCc1ccc2cccnc2c1O>>C=CCc1ccc2cccnc2c1OCc1ccccc1 -US20140100231A1,6,COc1ccc(Cn2cnc(C(F)(F)F)c(Oc3cc(C#N)cc(OC(F)F)c3)c2=O)cc1>>N#Cc1cc(Oc2c(C(F)(F)F)nc[nH]c2=O)cc(OC(F)F)c1 -US20120101134A1,6,CCOC(=O)CCCc1cccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c1C(F)(F)F>>CC(C)Oc1ccc(-c2nc(-c3cccc(CCCC(=O)O)c3C(F)(F)F)no2)cc1C#N -US07671056B2,1,Brc1csc2ccccc12.COc1ccccc1N1CCN(C2CCNCC2)CC1>>COc1ccccc1N1CCN(C2CCN(c3csc4ccccc34)CC2)CC1 -US20130296276A2,8,OCc1cncnc1-c1ccc(F)cc1>>O=Cc1cncnc1-c1ccc(F)cc1 -US20090275578A1,7,Cc1cc(C#CCN2CCN(C)CC2)cc2c1C(=O)N(Cc1ccc(OC(F)(F)F)cc1)C2>>Cc1cc(CCCN2CCN(C)CC2)cc2c1C(=O)N(Cc1ccc(OC(F)(F)F)cc1)C2 -US06087480,7,O=C1N=c2ccc([N+](=O)[O-])cc2=N1>>Nc1ccc2c(c1)=NC(=O)N=2 -US06506901B2,6,CCOC(=O)c1cnn(-c2ccc(S(=O)(=O)N3CCC(CNC[C@H](O)c4ccc(O)c(NS(C)(=O)=O)c4)CC3)cc2)c1>>CS(=O)(=O)Nc1cc([C@@H](O)CNCC2CCN(S(=O)(=O)c3ccc(-n4cc(C(=O)O)cn4)cc3)CC2)ccc1O -US08138337B2,2,C=CC[C@H](CC(=O)O)NC(=O)NCc1ccccc1.CCOC(CN(Cc1ccccc1)C(=O)C(N)Cc1ccc(OC(C)(C)C)cc1)OCC>>C=CCC(CC(=O)NC(Cc1ccc(OC(C)(C)C)cc1)C(=O)N(Cc1ccccc1)CC(OCC)OCC)NC(=O)NCc1ccccc1 -US07776875B2,2,CCCC(CCC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)O.CS(N)(=O)=O>>CCCC(CCC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)NS(C)(=O)=O -US20080269210A1,3,CC(C)(O)c1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1.CC1(C)OB(c2ccc(N)nc2)OC1(C)C>>CC(C)(O)c1cccc(-c2cc3nc(-c4ccc(N)nc4)nc(N4CCOCC4)c3s2)c1 -US20130280305A1,2,CCCCC/C=C\C/C=C\CCCCCCCC(=O)O[C@@H]1CNC[C@H]1OC(=O)CCCCCCC/C=C\C/C=C\CCCCC.CN(C)CC(=O)O>>CCCCC/C=C\C/C=C\CCCCCCCC(=O)O[C@@H]1CN(C(=O)CN(C)C)C[C@H]1OC(=O)CCCCCCC/C=C\C/C=C\CCCCC -US20090270416A1,1,CN1CCC(O)CC1.N#Cc1cnc(NC(=O)Nc2cc(Cl)ccc2O)cn1>>CN1CCC(Oc2ccc(Cl)cc2NC(=O)Nc2cnc(C#N)cn2)CC1 -US20060247210A1,1,Cc1n[nH]c(N)c1-c1nc2ccc(CBr)cc2s1.NCCO>>Cc1n[nH]c(N)c1-c1nc2ccc(CNCCO)cc2s1 -US06156782,3,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1I.OB(O)c1ccccc1C(F)(F)F>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1ccccc1C(F)(F)F -US05602137,1,CCOC(=O)CN.CCc1cc(Cl)n2nccc2n1>>CCOC(=O)CNc1cc(CC)nc2ccnn12 -US20120283434A1,2,CS(=O)(=O)Cl.O=C1COCCN1c1ccc(N2C[C@H](CO)OC2=O)cc1>>CS(=O)(=O)OC[C@H]1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1 -US20100041892A1,7,CCOC(=O)/C=C/c1cc(C(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl>>CCOC(=O)CCc1cc(C(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl -US07208598B2,1,Clc1nc(Cl)c2ncn(C3CCSC3)c2n1.Nc1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(Nc2nc(Cl)nc3c2ncn3C2CCSC2)cc1 -US07390830B1,1,CN(C)c1ccc(C=O)cc1.O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NCC1CCNCC1>>CN(C)c1ccc(CN2CCC(CNC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)CC2)cc1 -US20080090796A1,1,CI.O=C(NCC1(CC2CC2)CCN(S(=O)(=O)c2c[nH]nn2)CC1)c1ccc(Cl)cc1Cl>>Cn1cc(S(=O)(=O)N2CCC(CNC(=O)c3ccc(Cl)cc3Cl)(CC3CC3)CC2)nn1 -US20080045521A1,6,COC(=O)[C@H](Cc1ccc(OCC(C)(C)c2ccc3c(n2)N(C(=O)OC(C)(C)C)CCC3)cc1)NC(=O)c1c(Cl)cccc1Cl>>COC(=O)[C@H](Cc1ccc(OCC(C)(C)c2ccc3c(n2)NCCC3)cc1)NC(=O)c1c(Cl)cccc1Cl -US08163768B2,7,CC(C)(C)[Si](C)(C)Oc1ccc([N+](=O)[O-])c(N)c1>>CC(C)(C)[Si](C)(C)Oc1ccc(N)c(N)c1 -US06887889B2,1,O=CC1CC1.O=S(=O)(NCC1(c2ccc(I)cc2)CCNCC1)c1ccc(F)c(Cl)c1>>O=S(=O)(NCC1(c2ccc(I)cc2)CCN(CC2CC2)CC1)c1ccc(F)c(Cl)c1 -US20100041654A1,1,Nc1ccc(F)c(Cl)c1.O=C(NCC1CCCC1)c1cnc(Cl)nc1C(F)(F)F>>O=C(NCC1CCCC1)c1cnc(Nc2ccc(F)c(Cl)c2)nc1C(F)(F)F -US03954871,2,Cc1csc(C(O)CNC(C)C)c1C.O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>Cc1csc(C(CNC(C)C)OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)c1C -US20050272744A1,6,COC1(Cc2ccccc2C)CCC(N2CCN(C(=O)OC(C)(C)C)CC2)CC1>>COC1(Cc2ccccc2C)CCC(N2CCNCC2)CC1 -US20050137236A1,6,CC(C)(C)OC(=O)N(CCc1ccc(-c2ccc(C(=O)NS(C)(=O)=O)c(OC3CCCCC3)c2)cc1)C[C@H](O)c1ccccc1>>CS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCNC[C@H](O)c3ccccc3)cc2)cc1OC1CCCCC1 -US20120277237A1,3,Brc1ncccn1.C#CCCc1ccccc1>>C(#Cc1ncccn1)CCc1ccccc1 -US20140206681A1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.NC(=O)N/N=C/C(=O)C(F)(F)F>>CCOC(=O)/C=C(\C=N\NC(N)=O)C(F)(F)F -US20130137687A1,7,CC[C@H](NC(=O)OC(C)(C)C)[C@H](OC(C)=O)C(=O)NC1CC1>>CC[C@H](NC(=O)OC(C)(C)C)[C@H](O)C(=O)NC1CC1 -US20110319378A1,2,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CN2CCNCC2)C1=O.O=S(=O)(Cl)C1CC1>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CN2CCN(S(=O)(=O)C3CC3)CC2)C1=O -US20110112135A1,1,CCc1nc2c(C(F)(F)F)cccn2c1-c1cccc(O)c1.COc1ccc(CN(C)S(=O)(=O)c2cccc(Br)c2)cc1>>CCc1nc2c(C(F)(F)F)cccn2c1-c1cccc(Oc2cccc(S(=O)(=O)N(C)Cc3ccc(OC)cc3)c2)c1 -US20140171435A1,3,CCS(=O)(=O)c1ccc(-c2cc(B3OC(C)(C)C(C)(C)O3)ccc2Cl)c(OC)c1.CCn1cnc2c(Cl)cnnc21>>CCn1cnc2c(-c3ccc(Cl)c(-c4ccc(S(=O)(=O)CC)cc4OC)c3)cnnc21 -US20050182050A1,7,O=[N+]([O-])c1ccc(-c2cnns2)cc1>>Nc1ccc(-c2cnns2)cc1 -US20140194431A1,6,CC(C)(C)[Si](C)(C)OCCN(C(=O)c1nc(CC2(c3ccccc3)CCCC2)nc(O)c1OCc1ccccc1)C1CCOCC1>>O=C(c1nc(CC2(c3ccccc3)CCCC2)nc(O)c1OCc1ccccc1)N(CCO)C1CCOCC1 -US07705028B2,7,O=C(O)CCc1c(Cl)cccc1Cl>>OCCCc1c(Cl)cccc1Cl -US20070244125A1,1,O=C(c1ccc2[nH]c(C(=O)N3CCC(F)(F)CC3)cc2c1)N1CCC(N2CCCCC2)CC1.OB(O)c1ccnc(Cl)c1>>O=C(c1ccc2c(c1)cc(C(=O)N1CCC(F)(F)CC1)n2-c1ccnc(Cl)c1)N1CCC(N2CCCCC2)CC1 -US04743616,2,COC(=O)[C@@H]1CCCN1.O=C(Cl)Cc1ccccc1>>COC(=O)[C@@H]1CCCN1C(=O)Cc1ccccc1 -US20150087823A1,2,CCCCCCC/C=C/C(=O)O.Clc1ccc(N2CCNCC2)cc1>>CCCCCCC/C=C/C(=O)N1CCN(c2ccc(Cl)cc2)CC1 -US20120142705A1,2,Nc1nccs1.O=C1C(=O)N(C(CC2CCCC2)C(=O)O)c2ccc(Cl)cc21>>O=C1C(=O)N(C(CC2CCCC2)C(=O)Nc2nccs2)c2ccc(Cl)cc21 -US20020115721A1,6,C[C@H](C[C@H](NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>C[C@H](C[C@H](N)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US20150237859A1,1,CC(C)(C)OC(=O)N1CCC(c2nc(C(=O)O)cs2)CC1.Oc1cccc2ccccc12>>CC(C)(C)OC(=O)N1CCC(c2nc(C(=O)Oc3cccc4ccccc34)cs2)CC1 -US20140235855A1,3,CN(C)C=O.COc1ccc2ncc(Cl)c(Br)c2c1>>COc1ccc2ncc(Cl)c(C=O)c2c1 -US20090030012A1,6,CC(C)(C)OC(=O)N1CCC(c2nccc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)CC1>>FC(F)(F)c1cc(-c2ccnc(C3CCNCC3)n2)cc(C(F)(F)F)c1 -US07074932B2,2,CC(C)N(C(=O)Cl)C(C)C.OCC#Cc1cnc2ccccc2c1>>CC(C)N(C(=O)OCC#Cc1cnc2ccccc2c1)C(C)C -US05556864,3,O=CC=Cc1ccccc1.c1ccc(COc2ccccc2C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>C(C=Cc1ccccc1OCc1ccccc1)=Cc1ccccc1 -US05998622,2,CN1CCC(c2c[nH]c3ccc(N)nc23)CC1.O=C(Cl)c1ccccc1>>CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccccc4)nc23)CC1 -US08183246B2,1,CCc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1.COC(=O)CCCCC(C)O>>CCc1ccc(-c2c(-c3ccccc3)oc3ncnc(OC(C)CCCCC(=O)OC)c23)cc1 -US07932245B2,2,C[C@H](N)C(N)=O.O=C(O)C1CC12CCCCC2>>C[C@H](NC(=O)[C@H]1CC12CCCCC2)C(N)=O -US05292771,3,CC(=O)Nc1ccc(C=O)cc1.O=C(CC(=O)C1CC1)C1CC1>>CC(=O)Nc1ccc(C=C(C(=O)C2CC2)C(=O)C2CC2)cc1 -US07345070B2,6,CCOC(=O)C(C)(Cc1ccc(OCc2ccccc2)cc1)Oc1ccccc1>>CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccccc1 -US20080287517A1,2,C=CCOc1c(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(O)cc3)c2C)ccc(F)c1F.O=S(=O)(Cl)CCC(F)(F)F>>C=CCOc1c(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(OS(=O)(=O)CCC(F)(F)F)cc3)c2C)ccc(F)c1F -US20120289522A1,3,CCOC(=O)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cc1noc(-c2ccc(Br)cc2)c1[C@H](O)CSCc1ccccc1>>CCOC(=O)Cc1ccc(-c2ccc(-c3onc(C)c3[C@H](O)CSCc3ccccc3)cc2)cc1 -US04983211,1,CCC(=O)C1=C(O)CC(c2ccc(S)cc2)CC1=O.Fc1cc(C(F)(F)F)cnc1F>>CCC(=O)C1=C(O)CC(c2ccc(Sc3ncc(C(F)(F)F)cc3F)cc2)CC1=O -US20060040985A1,6,CN(CCC1(O)CCN(Cc2ccccc2)CC1)c1ccc(C(=O)OC(C)(C)C)cc1>>CN(CCC1(O)CCNCC1)c1ccc(C(=O)OC(C)(C)C)cc1 -US20090227560A1,2,COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)O)c1-c1ccccc1.O=C(OCc1ccccc1)N1CCN[C@H](CCOc2ccccc2Cl)C1>>COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCN(C(=O)OCc3ccccc3)C[C@H]2CCOc2ccccc2Cl)c1-c1ccccc1 -US08026257B2,1,C=O.Cn1ncc2cc(C(F)(F)F)cc(COCC3(c4ccc(F)cc4)CCNCC3)c21>>CN1CCC(COCc2cc(C(F)(F)F)cc3cnn(C)c23)(c2ccc(F)cc2)CC1 -US20100292212A1,1,O=[N+]([O-])c1ccc(F)cc1.OCC(F)(F)F>>O=[N+]([O-])c1ccc(OCC(F)(F)F)cc1 -US20140296201A1,6,CN(CCN[C@@H]1CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1)C(=O)OC(C)(C)C>>CNCCN[C@@H]1CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1 -US05216156,1,CON1C(C)(C)CC(CCCCNc2nc(Cl)nc(NCCCCC3CC(C)(C)N(OC)C(C)(C)C3)n2)CC1(C)C.NCCO>>CON1C(C)(C)CC(CCCCNc2nc(NCCO)nc(NCCCCC3CC(C)(C)N(OC)C(C)(C)C3)n2)CC1(C)C -US20110092526A1,9,C[C@H](c1ccccc1)N1C[C@H](C(=O)O)CC1=O.N>>C[C@H](c1ccccc1)N1C[C@H](C(N)=O)CC1=O -US20060223801A1,8,CONC(=O)c1cc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)CC2)nc(SC)n1.O=C(OO)c1cccc(Cl)c1>>CONC(=O)c1cc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)CC2)nc(S(C)=O)n1 -US20070082880A1,2,CS(=O)(=O)Cl.Cc1c(Nc2c(C#N)cnc3sc(C4=CCNCC4)cc23)ccc2[nH]ccc12>>Cc1c(Nc2c(C#N)cnc3sc(C4=CCN(S(C)(=O)=O)CC4)cc23)ccc2[nH]ccc12 -US08304557B2,2,CCN=C=O.Cc1cc(NC(=O)c2cc(C)nn2C)cc(Oc2ccc3nc(N)cn3c2)c1>>CCNC(=O)Nc1cn2cc(Oc3cc(C)cc(NC(=O)c4cc(C)nn4C)c3)ccc2n1 -US04661635,2,CNC(C)CCc1cc(OC)ccc1I.COc1ccc(CC(=O)Cl)cc1OC>>COc1ccc(I)c(CCC(C)N(C)C(=O)Cc2ccc(OC)c(OC)c2)c1 -US08691840B2,2,Nc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1.O=S(=O)(Cl)c1ccccc1>>O=C(Nc1ccc(-c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1)[C@H]1CN2CCC1CC2 -US20090023789A1,8,C[N+](C)(C)[O-].FC(F)(F)CCCCCBr>>O=CCCCCC(F)(F)F -US06838463B2,1,CC#CCOc1cc(Nc2ccccc2)ncn1.CCCI>>CC#CCOc1cc(N(CCC)c2ccccc2)ncn1 -US04701548,2,O=C(O)CS.OCCc1ccccc1>>O=C(CS)OCCc1ccccc1 -US06344462B1,1,Cc1ccc([N+](=O)[O-])c(C)c1CCl.Cc1ccc2cccc(O)c2n1>>Cc1ccc2cccc(OCc3c(C)ccc([N+](=O)[O-])c3C)c2n1 -US20050096337A1,1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1.COCc1nc(-c2ccc(C(F)(F)F)cc2)nc(C2CC2)c1CCl>>CCOC(=O)C(C)(C)Oc1ccc(OCc2c(COC)nc(-c3ccc(C(F)(F)F)cc3)nc2C2CC2)cc1 -US20060189661A1,6,COC(=O)c1cc(I)cc(C#N)c1>>N#Cc1cc(I)cc(C(=O)O)c1 -US06194396B1,2,CC(C)(C)C(O[SiH](c1ccccc1)c1ccccc1)c1c(Cl)ccc(N)c1Cl.O=C(Cl)CN1C(=O)c2ccccc2C1=O>>CC(C)(C)C(O[SiH](c1ccccc1)c1ccccc1)c1c(Cl)ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)c1Cl -US05648373,1,BrCCCCCCCCBr.c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1>>BrCCCCCCCCn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1 -US20110118354A1,1,C=C(C)C.COC(=O)C1=CCC(CO)CC1(C)c1ccc(Cl)c(C(F)(F)F)c1>>COC(=O)C1=CCC(COC(C)(C)C)CC1(C)c1ccc(Cl)c(C(F)(F)F)c1 -US08877747B2,3,COc1ccc(B(O)O)cn1.CS(=O)(=O)N1CCN(CCCOc2ccc3c(c2)C(=O)C(Br)=C3c2ccc(F)cc2F)CC1>>COc1ccc(C2=C(c3ccc(F)cc3F)c3ccc(OCCCN4CCN(S(C)(=O)=O)CC4)cc3C2=O)cn1 -US04820798,4,CC(C)(c1ccc(N)cc1)c1ccc(O)cc1.O=C1C=CC(=O)O1>>CC(C)(c1ccc(O)cc1)c1ccc(N2C(=O)C=CC2=O)cc1 -US08071588B2,3,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CN(Cc1ccc(C)c(Br)c1)C(=O)C1(C(N)=O)CC1.CN1CCC(Cc2cccc(B3OC(C)(C)C(C)(C)O3)c2)CC1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CN(Cc1ccc(C)c(-c2cccc(CC3CCN(C)CC3)c2)c1)C(=O)C1(C(N)=O)CC1 -US20140005146A1,1,C[C@@H](N)C(O)C1CC1.NC(=O)c1cnn2cc(Br)cc2c1Cl>>C[C@@H](Nc1c(C(N)=O)cnn2cc(Br)cc12)C(O)C1CC1 -US08058269B2,6,COC(=O)C1Cc2ccc(OC)cc2N1C1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc21>>COc1ccc2c(c1)N(C1(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc31)C(C(=O)O)C2 -US20090209556A1,7,CCOC(=O)c1ccc(C2CCC3(CC2)OCCO3)cc1>>OCc1ccc(C2CCC3(CC2)OCCO3)cc1 -US20060052597A1,2,O=C(O)C1CCCCCC1.O=C(c1ccc(OCCCN2CCCCC2)cc1)N1CCNCC1>>O=C(c1ccc(OCCCN2CCCCC2)cc1)N1CCN(C(=O)C2CCCCCC2)CC1 -US20040220188A1,3,O=C1CC(=O)N(c2ccc(-c3ccccc3)cc2)N1.O=Cc1ccco1>>O=C1NN(c2ccc(-c3ccccc3)cc2)C(=O)C1=Cc1ccco1 -US06048864,1,CC(=O)N1CCCN(C(=O)N2CCOCC2)CC1.COc1cc(N)c(C#N)c(OC2CCC2)c1>>COc1cc(N=C(C)N2CCCN(C(=O)N3CCOCC3)CC2)c(C#N)c(OC2CCC2)c1 -US20020193367A1,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1.CC(C)(C)OC(=O)Nc1cc(N2CCC2)c(C(F)(F)F)cc1N>>CC(C)(C)OC(=O)Nc1cc(N2CCC2)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1 -US08202885B2,7,CN(CC[C@]1(O)C[C@H]2CC[C@@H]1C=C2c1ccccc1)C(=O)CCc1nc(-c2ccccc2)c(-c2ccccc2)n1COCC[Si](C)(C)C>>CN(CCCc1nc(-c2ccccc2)c(-c2ccccc2)n1COCC[Si](C)(C)C)CCC1(O)CC2CCC1C=C2c1ccccc1 -US20150259366A1,6,COC(=O)CN(Cc1ccccc1)S(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)N(CC(=O)O)Cc2ccccc2)cc1 -US08691848B2,2,CC(C)(C)C(=O)Cl.CC(NC(=O)c1ccc(N)c(Cl)c1)C(=O)N1CCCC1C(=O)NC1CC(=O)OC1OCc1ccccc1>>CC(NC(=O)c1ccc(NC(=O)C(C)(C)C)c(Cl)c1)C(=O)N1CCCC1C(=O)NC1CC(=O)OC1OCc1ccccc1 -US07273875B2,6,CCOC(=O)C1CCC(c2cc3cccnc3c(-c3cccc(F)c3)n2)CC1>>O=C(O)C1CCC(c2cc3cccnc3c(-c3cccc(F)c3)n2)CC1 -US20140206682A1,2,COC(=O)c1ccc(F)c(N)c1.Cc1ccn2c(C(=O)O)cnc2c1>>COC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(C)ccn23)c1 -US08242280B2,3,CN(C(=O)OC(C)(C)C)C(C(=O)O)c1cccc(Br)c1.COc1ccccc1-c1nn(COCC[Si](C)(C)C)c2ncc(B3OC(C)(C)C(C)(C)O3)cc12>>COc1ccccc1-c1nn(COCC[Si](C)(C)C)c2ncc(-c3cccc(C(C(=O)O)N(C)C(=O)OC(C)(C)C)c3)cc12 -US20050267095A1,2,CS(=O)(=O)Cl.NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1>>CS(=O)(=O)NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1 -US20090221567A1,2,CC(C)OC(=O)Cl.CC1(N2CCC(N3C(=O)NC[C@H]4CCCC[C@@H]43)CC2)CCNCC1>>CC(C)OC(=O)N1CCC(C)(N2CCC(N3C(=O)NC[C@H]4CCCC[C@@H]43)CC2)CC1 -US20100125064A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=CC1CCCC1>>CC(C)(C)OC(=O)N1CCN(CC2CCCC2)CC1 -US20060019961A1,6,CC[C@@H]1C(=O)N(C2CCCC2)c2ccc(F)cc2N1C(=O)c1ccc(OC)cc1>>CC[C@@H]1C(=O)N(C2CCCC2)c2ccc(F)cc2N1C(=O)c1ccc(O)cc1 -US20100197681A1,1,NC1CCCC(O)C1.O=C(Nc1nc2cccc(Cl)n2n1)c1cccnc1>>O=C(Nc1nc2cccc(NC3CCCC(O)C3)n2n1)c1cccnc1 -US06642395B1,7,O=C(O)[C@H](O)c1cccc(Cl)c1>>OC[C@H](O)c1cccc(Cl)c1 -US09139589B2,3,C=CCB1OC(C)(C)C(C)(C)O1.COC(=O)c1sc(-c2c(C)nn3ccccc23)nc1OS(=O)(=O)C(F)(F)F>>C=CCc1nc(-c2c(C)nn3ccccc23)sc1C(=O)OC -US20070027163A1,2,CN(C)CCN.O=C(O)Cn1cc(C(=O)N2CCC(c3ccccc3OC(F)(F)F)CC2)c2ccc(Cl)cc21>>CN(C)CCNC(=O)Cn1cc(C(=O)N2CCC(c3ccccc3OC(F)(F)F)CC2)c2ccc(Cl)cc21 -US20100216788A1,6,COc1cccc(-c2nc(C(C)(C)C)cs2)c1>>CC(C)(C)c1csc(-c2cccc(O)c2)n1 -US07745438B2,1,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)COC(CI)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CC(c2ccccc2)(c2ccccc2)OC[C@@H]1COCc1ccccc1 -US20090325930A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(OC)cc1[N+](=O)[O-].COc1ccc2c(c1)C=C(OS(=O)(=O)C(F)(F)F)CC2>>COc1ccc2c(c1)C=C(c1ccc(OC)cc1[N+](=O)[O-])CC2 -US08372864B2,2,CCCC(CCC)N1CCc2c(C(=O)O)cccc2C1=O.N[C@@H](Cc1ccccc1)[C@H](O)CNC1(c2cccc(C(F)(F)F)c2)CC1>>CCCC(CCC)N1CCc2c(C(=O)N[C@@H](Cc3ccccc3)[C@H](O)CNC3(c4cccc(C(F)(F)F)c4)CC3)cccc2C1=O -US20100210642A1,3,C#Cc1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12.O=S(=O)(NCCO)c1cc(Br)c(F)cc1F>>O=S(=O)(NCCO)c1cc(C#Cc2cnn3c(C(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)c(F)cc1F -US08883782B2,1,C[O-].NC1=N[C@@]2(CO1)c1cc(-c3cccnc3)ccc1Oc1c2cc(-c2cccnc2)nc1F>>COc1nc(-c2cccnc2)cc2c1Oc1ccc(-c3cccnc3)cc1[C@@]21COC(N)=N1 -US20110269712A1,6,CCOC(=O)c1csc(N2CCN(C(=O)Cn3nc(C(F)(F)F)cc3C)CC2)n1>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCN(c2nc(C(=O)O)cs2)CC1 -US20110105566A1,3,C#CC1CC1.CSc1cccc(C(=NOCc2csc(Br)n2)c2nnnn2C)c1>>CSc1cccc(C(=NOCc2csc(C#CC3CC3)n2)c2nnnn2C)c1 -US20090221611A1,2,CN(C)C(=O)Cl.COC(=O)C1CCNCC1>>COC(=O)C1CCN(C(=O)N(C)C)CC1 -US20090093479A1,1,NC(=O)c1cc(Br)cc(Br)c1.Nc1cccnc1>>NC(=O)c1cc(Br)cc(Nc2cccnc2)c1 -US20150025253A1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(c1cc(Cl)c(F)c(Cl)c1F)C(F)(F)F>>C=C(c1cc(Cl)c(F)c(Cl)c1F)C(F)(F)F -US20090137557A1,7,Cn1ncc(C(=O)NCCc2cccc(F)c2)c1[N+](=O)[O-]>>Cn1ncc(C(=O)NCCc2cccc(F)c2)c1N -US20090036425A1,1,BrCc1ccccc1.Oc1ccc(Br)cc1F>>Fc1cc(Br)ccc1OCc1ccccc1 -US04112100,7,O=[N+]([O-])c1ccc(NC(=S)NCc2ccncc2)cc1>>Nc1ccc(NC(=S)NCc2ccncc2)cc1 -US20120022254A1,2,Nc1cnccc1O.O=C(O)c1ccc([N+](=O)[O-])s1>>O=C(Nc1cnccc1O)c1ccc([N+](=O)[O-])s1 -US20100105705A1,1,Cn1cnc2c(Nc3ccc(Cl)cc3)nc(Cl)nc21.c1cn[nH]c1>>Cn1cnc2c(Nc3ccc(Cl)cc3)nc(-n3cccn3)nc21 -US04305717,7,COc1ccc([N+](=O)[O-])cc1NCC(N)=O>>COc1ccc(N)cc1NCC(N)=O -US20010047014A1,1,ClCCOc1ccc(OCc2ccccc2)cc1.O[C@H]1CNCC[C@@]1(O)Cc1ccccc1>>O[C@H]1CN(CCOc2ccc(OCc3ccccc3)cc2)CC[C@@]1(O)Cc1ccccc1 -US20070037807A1,1,Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc(C)c2C(=O)O)cc1.O=C1OCC(Cl)O1>>Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc(C)c2C(=O)OC2COC(=O)O2)cc1 -US20090270412A1,3,C=O.CNCCc1cn(CC(=O)N2CCC(C)CC2)c2ccc(Cl)cc12>>CC1CCN(C(=O)Cn2c3c(c4cc(Cl)ccc42)CCN(C)C3)CC1 -US20060287275A1,1,NC1CCOC1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(NC4CCOC4)ncnc32)[C@@H](O)[C@H]1O -US20150087626A1,6,COC(=O)c1ccc(C2(NC(=O)[C@H]3CC(C)(C)CN3Cc3ccc(C(F)(F)F)cc3)CC2)cc1>>CC1(C)C[C@H](C(=O)NC2(c3ccc(C(=O)O)cc3)CC2)N(Cc2ccc(C(F)(F)F)cc2)C1 -US20120316147A1,2,CC(C)(N)c1ncon1.O=C(O)c1ccc(Cl)c(OCC2CC2)n1>>CC(C)(NC(=O)c1ccc(Cl)c(OCC2CC2)n1)c1ncon1 -US20050234081A1,2,COC(=O)CC(=O)Cl.CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2N)c1>>COC(=O)CC(=O)Nc1cccc(C)c1-c1cccc(S(=O)(=O)c2cc(C(=N)NC(=O)OC(C)(C)C)sc2SC)c1 -US08063046B2,2,CCN.COc1ccc(C(=O)O)cc1/C=C/c1ccc(Cl)cc1>>CCNC(=O)c1ccc(OC)c(/C=C/c2ccc(Cl)cc2)c1 -US20100113780A1,1,CC(C)Oc1ccc(B(O)O)cc1.CCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(C)n(-c2ccc(OC(C)C)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US08829052B2,1,Cc1cc(F)c(F)c(F)c1[N+](=O)[O-].Nc1ccc(I)cc1F>>Cc1cc(F)c(F)c(Nc2ccc(I)cc2F)c1[N+](=O)[O-] -US08519135B2,5,COC(=O)c1cccc([N+](=O)[O-])c1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cccc([N+](=O)[O-])c1NC(=O)C(F)(F)F -US20120270864A1,1,CO[C@H]1CN(CCOS(C)(=O)=O)CC[C@H]1NC(=O)OC(C)(C)C.N#Cc1ccc2ccc(=O)[nH]c2c1>>CO[C@H]1CN(CCn2c(=O)ccc3ccc(C#N)cc32)CC[C@H]1NC(=O)OC(C)(C)C -US07601850B2,7,CCC(CC)(c1ccc(OCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1cc(C)c(C(=O)OC)s1>>CCC(CC)(c1ccc(OCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1cc(C)c(CO)s1 -US08030354B2,3,COC(=O)c1cc(C2=CCCC2(C)C)c(OS(=O)(=O)C(F)(F)F)cc1F.COc1ccc(F)c(B(O)O)c1>>COC(=O)c1cc(C2=CCCC2(C)C)c(-c2cc(OC)ccc2F)cc1F -US20140065103A1,6,COC(=O)c1sc(C#CC(C)C)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCN(C(=O)CCCCCNC(=O)OC(C)(C)C)CC1>>CC(C)C#Cc1cc(N(C(=O)[C@@H]2CC[C@@H](C)CC2)C2CCN(C(=O)CCCCCNC(=O)OC(C)(C)C)CC2)c(C(=O)O)s1 -US20100130470A1,5,Brc1cnc2c(c1)CNCCN2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCNc2ncc(Br)cc2C1 -US07157463B2,6,COC(=O)CC1c2ccccc2CN1C(C)C>>CC(C)N1Cc2ccccc2C1CC(=O)O -US06432950B1,1,NCc1ccccc1.O=[N+]([O-])c1cc2c(Cl)nc(-c3ccncc3)nc2s1>>O=[N+]([O-])c1cc2c(NCc3ccccc3)nc(-c3ccncc3)nc2s1 -US20130029991A1,2,CCN(CC)CCCN.O=C(O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1>>CCN(CC)CCCNC(=O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1 -US07423030B2,6,COc1ccc2c(COCc3ccccc3)nnc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1>>COc1ccc2c(CO)nnc(NC3CCN(Cc4ccc5ccccc5c4)CC3)c2c1 -US05801170,2,COc1ccc(N)cc1OCCCN(C)C.Cc1nc(-c2ccc(-c3ccc(C(=O)O)cc3)c(C)c2)no1>>COc1ccc(NC(=O)c2ccc(-c3ccc(-c4noc(C)n4)cc3C)cc2)cc1OCCCN(C)C -US09120749B2,3,CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)CC1.COc1cc(B2OC(C)(C)C(C)(C)O2)cc(Cl)c1O>>COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(N[C@@H]4CC[C@@H](N(C)C(=O)OC(C)(C)C)CC4)c3c2)cc(Cl)c1O -US08178520B2,6,C=CCCc1nnc(N[C@H](C(=O)OC)C(C)C)o1>>C=CCCc1nnc(N[C@H](C(=O)O)C(C)C)o1 -US20110294792A1,7,O=C(O)c1cc(F)ccc1[N+](=O)[O-]>>O=[N+]([O-])c1ccc(F)cc1CO -US20120245171A1,2,COc1ncc(Br)cc1N.CS(=O)(=O)Cl>>COc1ncc(Br)cc1NS(C)(=O)=O -US06951848B2,6,Cc1[nH]c2ccc(CCNC(=O)OC(C)(C)C)cc2c1C(=O)OCc1ccccc1>>Cc1[nH]c2ccc(CCN)cc2c1C(=O)OCc1ccccc1 -US04115385,2,CC1(C)S[C@@H]2C(N)C(=O)N2C1c1nnn[nH]1.O=C([O-])C(C(=O)Oc1ccc2c(c1)CCC2)c1ccccc1>>CC1(C)S[C@@H]2C(NC(=O)C(C(=O)Oc3ccc4c(c3)CCC4)c3ccccc3)C(=O)N2C1c1nnn[nH]1 -US20050227953A1,1,C=O.COc1ccc2c(c1)CCC13CNCC1CCC23>>COc1ccc2c(c1)CCC13CN(C)CC1CCC23 -US08569494B2,1,CC(C)(O)c1ccc(Br)cn1.C[Sn](C)(C)[Sn](C)(C)C>>CC(C)(O)c1ccc([Sn](C)(C)C)cn1 -US20070197618A1,1,Clc1nc2ccccc2[nH]1.NCC(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>Clc1ccc(C(CNc2nc3ccccc3[nH]2)c2ccc(Cl)cc2)cc1 -US20100144760A1,8,Cc1ccc(-c2ncccn2)nc1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(-c2ncccn2)[n+]([O-])c1 -US07067534B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CCCCO)CC2)c1.Cc1onc(-c2ccccc2)c1C(=O)Cl>>Cc1onc(-c2ccccc2)c1C(=O)OCCCCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1 -US04357351,2,CCCCCCCN=C(NCCCCCCC)SCC.Cc1csc(N=C=O)c1>>CCCCCCCN=C(SCC)N(CCCCCCC)C(=O)Nc1cc(C)cs1 -US05556867,7,COC(=O)C1COC(c2c(F)cccc2F)=N1>>OCC1COC(c2c(F)cccc2F)=N1 -US20090048258A1,6,COC(=O)c1cc(-c2ccccc2)nc(-c2ccccc2)n1>>O=C(O)c1cc(-c2ccccc2)nc(-c2ccccc2)n1 -US08748462B2,9,COC(=O)C1Cc2cnc(OCc3ccccc3)cc2C1=O>>O=C1CCc2cnc(OCc3ccccc3)cc21 -US05552414,1,COc1cc2c(cc1OCCCCl)CCCC2=O.Fc1ccc2c(C3CCNCC3)noc2c1>>COc1cc2c(cc1OCCCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2=O -US07728025B2,1,N#Cc1ccc(Br)cn1.Oc1cc2[nH]c(-c3cnccn3)nc2cc1Oc1ccccc1F>>N#Cc1ccc(Oc2cc3[nH]c(-c4cnccn4)nc3cc2Oc2ccccc2F)cn1 -US20130165494A1,2,Cc1c(CC(=O)O)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1.N[C@@H](CO[N+](=O)[O-])C(=O)O>>Cc1c(CC(=O)N[C@@H](CO[N+](=O)[O-])C(=O)O)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 -US20140235643A1,7,CC(=O)c1nc2cccc(C)c2nc1-c1ccccc1>>Cc1cccc2nc(C(C)O)c(-c3ccccc3)nc12 -US08445674B2,7,COC(=O)[C@H](CCC(=O)N1CCC2(CC2)[C@H](O)C1)N1CCN(C(=O)Nc2ccc(C(F)(F)F)c(C(F)(F)F)c2)[C@@H](C)C1=O>>C[C@H]1C(=O)N([C@H](CO)CCC(=O)N2CCC3(CC3)[C@H](O)C2)CCN1C(=O)Nc1ccc(C(F)(F)F)c(C(F)(F)F)c1 -US20090163508A1,2,O=C(Nc1cccnn1)OCC(Cl)(Cl)Cl.c1ccc(-c2cncc(N3CCNCC3)n2)cc1>>O=C(Nc1cccnn1)N1CCN(c2cncc(-c3ccccc3)n2)CC1 -US20150105429A1,2,CC(C)CNCc1cnc(Br)s1.O=S(=O)(Cl)Cc1ccccc1>>CC(C)CN(Cc1cnc(Br)s1)S(=O)(=O)Cc1ccccc1 -US20100249402A1,4,CNC(N)=S.N#Cc1ccc(OCCCCCOc2ccc(C(=O)CBr)cc2)cc1>>CNc1nc(-c2ccc(OCCCCCOc3ccc(C#N)cc3)cc2)cs1 -US07893099B2,7,CCOC(=O)[C@@H]1CC(=O)C[C@H]1C(=O)N1CCOCC1>>CCOC(=O)[C@@H]1C[C@H](O)C[C@H]1C(=O)N1CCOCC1 -US04918207,7,O=C(CCCl)c1ccccc1>>O[C@@H](CCCl)c1ccccc1 -US04021557,1,CN(CCCl)Cc1ccccc1.CN1C(=O)c2cccnc2Nc2ccccc21>>CN(CCN1c2ccccc2N(C)C(=O)c2cccnc21)Cc1ccccc1 -US20150119404A1,3,C#CC[C@@]1(NC(=O)OC(C)(C)C)CCN(C)C1=O.CCOc1ccc(F)c(-c2cc(C)nc(I)n2)c1>>CCOc1ccc(F)c(-c2cc(C)nc(C#CC[C@@]3(NC(=O)OC(C)(C)C)CCN(C)C3=O)n2)c1 -US04891429,1,Cc1cccc(C)c1N(CCCc1cccnc1)C(=O)CCl.Cc1ncc[nH]1>>Cc1cccc(C)c1N(CCCc1cccnc1)C(=O)Cn1ccnc1C -US08501732B2,2,CNOC.O=C(O)c1ccc(Cl)cc1Nc1ccccc1>>CON(C)C(=O)c1ccc(Cl)cc1Nc1ccccc1 -US04343811,6,CCCn1c(-c2ccncc2)c(C)c2cc(OC(C)(C)C(=O)OCC)ccc21>>CCCn1c(-c2ccncc2)c(C)c2cc(OC(C)(C)C(=O)O)ccc21 -US20100298324A1,9,COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)n1.N>>COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(N)=O)ccc3c2=O)n1 -US20050239781A1,7,Cc1cncc2[nH]c3c([N+](=O)[O-])cc(Cl)cc3c12>>Cc1cncc2[nH]c3c(N)cc(Cl)cc3c12 -US20070219210A1,2,CNOC.Cc1ccc(C(=O)O)cn1>>CON(C)C(=O)c1ccc(C)nc1 -US20010053851A1,2,CCC(C)(O)C#Cc1ccc(C(CC2CCCC2)C(=O)O)cc1.Nc1nccs1>>CCC(C)(O)C#Cc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1 -US20110172099A1,7,CC(Cc1cccc(Cl)c1Cl)CC(C(=O)C(C)(C)C)n1cncn1>>CC(Cc1cccc(Cl)c1Cl)CC(C(O)C(C)(C)C)n1cncn1 -US20100063058A1,1,COc1cc(C(F)(F)F)nnc1NC1CCNCC1.FC(F)(F)c1cccc(CBr)c1>>COc1cc(C(F)(F)F)nnc1NC1CCN(Cc2cccc(C(F)(F)F)c2)CC1 -US05166170,7,Nc1cc(C(F)(F)F)ccc1-c1cc2ccccc2[nH]1>>Nc1cc(C(F)(F)F)ccc1C1Cc2ccccc2N1 -US05206053,1,C=COCCCl.OCc1ccc(O)cc1>>C=COCCOc1ccc(CO)cc1 -US20150210688A1,4,COC(=O)c1ccc(C)c(C(=O)CBr)c1.COCC(=N)N>>COCc1ncc(-c2cc(C(=O)OC)ccc2C)[nH]1 -US20100093776A1,3,Clc1ccnc(Cl)n1.OB(O)c1cccc2[nH]ccc12>>Clc1nccc(-c2cccc3[nH]ccc23)n1 -US07879852B2,1,CC(C)(C)OC(=O)N1CC[C@H](N)C1.CC1(C)CCC(=O)CC1>>CC1(C)CCC(N[C@H]2CCN(C(=O)OC(C)(C)C)C2)CC1 -US08263606B2,3,COc1ccc(B(O)O)cc1.O=C1N(Cc2ccccn2)c2cccc(Br)c2C12COc1cc3c(cc12)OCCO3>>COc1ccc(-c2cccc3c2C2(COc4cc5c(cc42)OCCO5)C(=O)N3Cc2ccccn2)cc1 -US20090105283A1,4,Cc1cccc(N)c1C(=O)O.NC=O>>Cc1cccc2nc[nH]c(=O)c12 -US07582626B2,2,CCOC(=O)[C@@H]1CCCC[C@@H]1NCCC(C)(C)C.CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(CC(=O)O)N2>>CCOC(=O)[C@@H]1CCCC[C@@H]1N(CCC(C)(C)C)C(=O)CC1=NS(=O)(=O)c2cc(NS(C)(=O)=O)ccc2N1 -US06867221B2,1,COc1cc(-c2cncc(CCl)c2)cc(OC)c1OC.COc1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>COc1ccc(N(Cc2cncc(-c3cc(OC)c(OC)c(OC)c3)c2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US08415370B2,1,FC(F)(F)c1ccc(CBr)o1.O=C1Nc2cc3c(cc2C1=O)OCCO3>>O=C1C(=O)N(Cc2ccc(C(F)(F)F)o2)c2cc3c(cc21)OCCO3 -US04065563,7,O=[N+]([O-])c1ccc(-c2nc(-c3cccnc3)no2)cc1>>Nc1ccc(-c2nc(-c3cccnc3)no2)cc1 -US09073925B2,1,CN(N)c1cccc(Br)n1.O=C1CCN2CCC1CC2>>CN(/N=C1/CCN2CCC1CC2)c1cccc(Br)n1 -US20070244117A1,1,Nc1ccc(F)cc1C(=O)O.O=Cc1ccncc1>>O=C(O)c1cc(F)ccc1NCc1ccncc1 -US20140213578A1,1,CC(C)(C)OC(N)=O.O=S(=O)(NCCCN1c2ccccc2CCc2ccc(Cl)cc21)c1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)Nc1ccc2c(c1)N(CCCNS(=O)(=O)c1ccc(C(F)(F)F)cc1)c1ccccc1CC2 -US20080305169A1,2,Nc1cc(Cl)ccc1O.O=C(Cl)CCl>>O=C(CCl)Nc1cc(Cl)ccc1O -US08354426B2,6,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CCn2c(=O)ccc3ncc(F)cc32)CC1>>O=c1ccc2ncc(F)cc2n1CCN1CCC(NCc2cc3c(cn2)OCCO3)CC1 -US04968829,1,CCC(C)Sc1ccc(S)cc1.O=C1c2ccccc2C(=O)N1CCBr>>CCC(C)Sc1ccc(SCCN2C(=O)c3ccccc3C2=O)cc1 -US20150166483A1,7,Cc1nc2cc(C(C)(C)C)cc([N+](=O)[O-])c2o1>>Cc1nc2cc(C(C)(C)C)cc(N)c2o1 -US20100305133A1,1,CCCN.COC(=O)c1c(OC)ccc2nc(Cl)c(-c3ccccc3)nc12>>CCCNc1nc2ccc(OC)c(C(=O)OC)c2nc1-c1ccccc1 -US07595314B2,1,C1COCCN1.CC(=O)c1ccc(N2CCN(C(=O)c3cc(S(=O)(=O)N(C)C)ccc3Cl)CC2)c(F)c1>>CC(=O)c1ccc(N2CCN(C(=O)c3cc(S(=O)(=O)N(C)C)ccc3N3CCOCC3)CC2)c(F)c1 -US08278325B2,9,CCCCOC(=O)c1nc(Br)c2ccc(OC3CCCCC3)cc2c1O>>CCCCOC(=O)c1ncc2ccc(OC3CCCCC3)cc2c1O -US20140038989A1,2,CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)O)c3N2)cc1.NCc1ccc(F)cn1>>CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)NCc4ccc(F)cn4)c3N2)cc1 -US20070179318A1,1,Brc1ccc(-c2ccc(I)cc2)cc1.c1ccc(Nc2ccccc2)cc1>>Brc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1 -US20030199550A1,1,C1CCNCC1.CN(CC[C@@H]1CC[C@@H](/C=C/CCl)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1>>CN(CC[C@@H]1CC[C@@H](/C=C/CN2CCCCC2)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1 -US06395738B1,6,CCOC(=O)c1cc2c(C(=O)Nc3c(Cl)cncc3Cl)ccc(OC)c2o1>>COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(=O)O)oc12 -US20040058915A1,1,CCOC(=O)CBr.COc1ccc2c(c1)CCNC2=O>>CCOC(=O)CN1CCc2cc(OC)ccc2C1=O -US06548534B2,2,C=CCN.O=C(O)c1ccc([N+](=O)[O-])cc1Br>>C=CCNC(=O)c1ccc([N+](=O)[O-])cc1Br -US04598148,1,CC(C)I.COc1cc2c(cc1OC)-c1cc(=O)[nH]c(=O)n1CC2>>COc1cc2c(cc1OC)-c1cc(=O)n(C(C)C)c(=O)n1CC2 -US20070027173A1,1,Fc1cc(F)cc(CCl)c1.O=C1OC2(CCN(C(=O)c3c[nH]c4cc(Cl)ccc34)CC2)c2ccc(Br)cc21>>O=C1OC2(CCN(C(=O)c3cn(Cc4cc(F)cc(F)c4)c4cc(Cl)ccc34)CC2)c2ccc(Br)cc21 -US20100093767A1,2,CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)O.Nc1ccccc1NCc1ccccc1>>CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccccc1NCc1ccccc1 -US06992103B2,1,COC(=O)c1cc(O)cc(N2CCCC2=O)c1.COCCCCO>>COCCCCOc1cc(C(=O)OC)cc(N2CCCC2=O)c1 -US20070208020A1,6,CN(CC(=O)Nc1cccc(C(F)(F)F)c1)C(=O)OC(C)(C)C>>CNCC(=O)Nc1cccc(C(F)(F)F)c1 -US20080312226A1,2,CC(C)OC(=O)Cl.O=C(Nc1noc2ccccc12)N1CCNCC1>>CC(C)OC(=O)N1CCN(C(=O)Nc2noc3ccccc23)CC1 -US20070254869A1,7,CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2cc(Cl)ccc21>>CCN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2cc(Cl)ccc21 -US20130029942A1,1,CN.COc1ccc(N(C)c2nc(Cl)nc3c2CCC3)cc1>>CNc1nc2c(c(N(C)c3ccc(OC)cc3)n1)CCC2 -US04735952,7,Nc1ccc(C(=O)N2CCC(C(=O)c3ccc(F)cc3)CC2)cc1>>Nc1ccc(C(=O)N2CCC(C(O)c3ccc(F)cc3)CC2)cc1 -US06429207B1,7,Cc1ccc2cc([N+](=O)[O-])ccc2n1>>Cc1ccc2cc(N)ccc2n1 -US20120088750A1,3,CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(Br)c2s1.CN(C)C=O>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(C=O)c2s1 -US07550461B2,8,O=[N+]([O-])c1cccc(CO)c1Cl>>O=Cc1cccc([N+](=O)[O-])c1Cl -US07622474B2,6,CC(C)(C)OC(=O)Nc1ccc(-n2c(=O)[nH]c3ccccc3c2=O)cc1>>Nc1ccc(-n2c(=O)[nH]c3ccccc3c2=O)cc1 -US04225606,1,O=C1CCCC1.c1cnc(NC2CCNCC2)nc1>>c1cnc(NC2CCN(C3CCCC3)CC2)nc1 -US08324221B2,6,CC(O)c1cccc2c1C1(CCN(Cc3ccccc3)CC1)CN2C(=O)OC(C)(C)C>>CC(O)c1cccc2c1C1(CCN(Cc3ccccc3)CC1)CN2 -US20080154035A1,3,C=C(CCl)CN(OCc1ccccc1I)C(=O)OC(C)(C)C>>C=C1Cc2ccccc2CON(C(=O)OC(C)(C)C)C1 -US20070191385A1,3,CCC(=O)c1ccc(B(O)O)cc1.COC(=O)CNc1ccc(-n2cc(-c3ccc(Cl)cc3Cl)nc2Cc2ccc(Br)cc2)cc1>>CCC(=O)c1ccc(-c2ccc(Cc3nc(-c4ccc(Cl)cc4Cl)cn3-c3ccc(NCC(=O)OC)cc3)cc2)cc1 -US20120190679A1,6,CC(C)(C)OC(=O)NC(CC#N)c1ccc(Cl)cc1>>N#CCC(N)c1ccc(Cl)cc1 -US20140080798A1,6,Cc1cnc(Nc2ccc(C3CN(C(=O)OC(C)(C)C)C3)cc2)nc1CCc1ccccc1CC(N)=O>>Cc1cnc(Nc2ccc(C3CNC3)cc2)nc1CCc1ccccc1CC(N)=O -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.C[C@H](CCl)COc1ccccc1Br>>CC(C)C(=O)Nc1cccc(C2CCN(C[C@@H](C)COc3ccccc3Br)CC2)c1 -US20130165445A1,3,CC(=O)c1cccc(Cl)c1.CCC(=O)C(=O)O>>CCC(O)(CC(=O)c1cccc(Cl)c1)C(=O)O -US07737141B2,2,C[C@@H](O)[C@H]1COC[C@@H](c2ccc(Cl)cc2)N1.O=C(O)c1ccc([N+](=O)[O-])cc1>>C[C@H](OC(=O)c1ccc([N+](=O)[O-])cc1)[C@H]1COC[C@@H](c2ccc(Cl)cc2)N1 -US20090054457A1,2,CSCC[C@@H](NC(=O)OCc1ccccc1)C(=O)O.Nc1ccc(Cl)cc1>>CSCC[C@@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc(Cl)cc1 -US20150099735A1,2,C1CCNC1.Cn1ncc(C(=O)O)c1C(=O)Nc1ccc2nc(N3CCOCC3)nn2c1>>Cn1ncc(C(=O)N2CCCC2)c1C(=O)Nc1ccc2nc(N3CCOCC3)nn2c1 -US20030191110A1,7,CCN1CCCC[C@H]1C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>CCN1CCCC[C@H]1CN1CCN(C(c2ccccc2)c2ccccc2)CC1 -US04913997,1,CC(=O)c1ccccc1.NNc1ccccc1>>CC(=NNc1ccccc1)c1ccccc1 -US05179077,1,CC(=O)CCl.CCCCCC(Br)C(=O)O>>CCCCCC(Br)C(=O)OCC(C)=O -US04767769,1,N#CCCCBr.Oc1cccc(CN2CCCCC2)c1Cl>>N#CCCCOc1cccc(CN2CCCCC2)c1Cl -US06211215B1,1,ClCc1coc(-c2cc3c(s2)CCCC3)n1.Oc1ccc(CCCn2ccnc2)cc1>>c1cn(CCCc2ccc(OCc3coc(-c4cc5c(s4)CCCC5)n3)cc2)cn1 -US06649611B2,1,CCN(CC)CCN.C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1C=O>>CCN(CC)CCNCc1cc(Cl)ccc1OCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C -US20060058308A1,1,Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(NCC4CCCCN4)n3)cccc2[nH]c1=O.O=CC1CC1>>Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(NCC4CCCCN4CC4CC4)n3)cccc2[nH]c1=O -US20100240660A1,6,COc1cc(C=CC(=O)c2ccccc2)ccc1C=CC(=O)OC(C)(C)C>>COc1cc(C=CC(=O)c2ccccc2)ccc1C=CC(=O)O -US08044211B2,1,CC(C)C[C@H](N)C(=O)OC1CCCC1.Cc1cc(C(=O)c2ccc(=O)n(-c3c(F)cc(OCCCOS(C)(=O)=O)cc3F)c2N)ccc1F>>Cc1cc(C(=O)c2ccc(=O)n(-c3c(F)cc(OCCCN[C@@H](CC(C)C)C(=O)OC4CCCC4)cc3F)c2N)ccc1F -US20100298347A1,6,CCOC(=O)c1cc(-c2ccsc2)c2ccc(OCc3ccccc3)cc2c1>>CCOC(=O)c1cc(-c2ccsc2)c2ccc(O)cc2c1 -US07482342B2,2,NCCCn1ccnc1.O=C(O)c1n[nH]c2ccccc12>>O=C(NCCCn1ccnc1)c1n[nH]c2ccccc12 -US20110046097A1,9,NO.O=Cc1cccc(I)c1F>>ON=Cc1cccc(I)c1F -US05789406,2,COc1ccccc1N=C=O.Nc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12>>COc1ccccc1NC(=O)Nc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12 -US20110034455A1,6,CCOC(=O)C1(Cc2ccccc2)CCCN(C(=O)c2ccccc2)C1>>O=C(c1ccccc1)N1CCCC(Cc2ccccc2)(C(=O)O)C1 -US20110124661A1,6,CC(C)(C)[Si](C)(C)OC[C@@H]1Cn2c(nc3cc(C#N)ccc32)O1>>N#Cc1ccc2c(c1)nc1n2C[C@@H](CO)O1 -US20070185079A1,2,CNC.O=C(Cl)c1cc(Cl)nc2ccccc12>>CN(C)C(=O)c1cc(Cl)nc2ccccc12 -US07626030B2,1,CC=O.COc1cc2nccc(Oc3ccc4c(N)nn(C)c4c3)c2cc1OC>>CCNc1nn(C)c2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 -US20070149546A1,1,CNCCO.Fc1cccc(COc2ccc(Nc3ncnc4cccc(OCCCl)c34)cc2Cl)c1>>CN(CCO)CCOc1cccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12 -US20060025474A1,1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(CCC(O)C(C)(C)C)c(C)c1.NCCBr>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(OCCN)c(C)c1 -US08133909B2,1,Cc1ccc(I)cc1OC(F)F.NCCc1ccc(C(F)(F)F)cn1>>Cc1ccc(NCCc2ccc(C(F)(F)F)cn2)cc1OC(F)F -US04080330,2,O=C(Cl)CCBr.c1ccc(C2CNc3ccccc32)cc1>>O=C(CCBr)N1CC(c2ccccc2)c2ccccc21 -US09018211B2,1,COc1cc(C(C)C=O)ccc1C#N.Cc1c(C(O)CN2CCNCC2)ccc2c1COC2=O>>COc1cc(C(C)CN2CCN(CC(O)c3ccc4c(c3C)COC4=O)CC2)ccc1C#N -US06881736B1,6,COC(=O)CC(Cc1ccc(OC(=O)OC(C)(C)C)cc1)c1nc(C(=O)OCc2ccccc2)co1>>COC(=O)CC(Cc1ccc(OC(=O)OC(C)(C)C)cc1)c1nc(C(=O)O)co1 -US07652051B2,2,Nc1nnc(-c2ccc(Oc3cccnc3)cc2)o1.O=C(Cl)c1ccccc1OC(F)(F)F>>O=C(Nc1nnc(-c2ccc(Oc3cccnc3)cc2)o1)c1ccccc1OC(F)(F)F -US20100022515A1,3,CC1(C)OB(c2ccc(CCc3nc(-c4ccc5c(c4)CCN(S(C)(=O)=O)C5)no3)cc2)OC1(C)C.Cc1ccc(Br)nc1>>Cc1ccc(-c2ccc(CCc3nc(-c4ccc5c(c4)CCN(S(C)(=O)=O)C5)no3)cc2)nc1 -US08344029B2,1,O=Cc1ccc(F)cc1.OCC(F)F>>O=Cc1ccc(OCC(F)F)cc1 -US20080132542A1,3,O=C(O)Cn1nnc(-c2cc(N3CCC(Oc4cc(Br)ccc4Cl)CC3)no2)n1.OB(O)c1ccc(OC(F)(F)F)cc1>>O=C(O)Cn1nnc(-c2cc(N3CCC(Oc4cc(-c5ccc(OC(F)(F)F)cc5)ccc4Cl)CC3)no2)n1 -US08217043B2,1,COC(=O)CC(=O)Cl.COC(=O)c1cc(Cl)cn1NCc1ccc(-c2ccccc2)cc1>>COC(=O)CC(=O)N(Cc1ccc(-c2ccccc2)cc1)n1cc(Cl)cc1C(=O)OC -US09108938B2,2,Cc1ncc(C(CN)N2CCC(F)(F)CC2)cn1.O=C(O)c1cccc(Cl)c1Cl>>Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)N2CCC(F)(F)CC2)cn1 -US04088652,2,CC(=O)N1CC2CC2(c2ccc(N)cc2)C1.CC(=O)[O-]>>CC(=O)Nc1ccc(C23CC2CN(C(C)=O)C3)cc1 -US20060241302A1,7,COC(=O)/C=C/c1cc(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(Cl)cc2)c(F)cn1>>COC(=O)CCc1cc(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(Cl)cc2)c(F)cn1 -US08119663B2,4,CCOC(=O)C(=O)CBr.CCc1ccc(C2CC(C(N)=S)CN(C(=O)N3CCOCC3)C2)cc1>>CCOC(=O)c1csc(C2CC(c3ccc(CC)cc3)CN(C(=O)N3CCOCC3)C2)n1 -US20150175563A1,6,CCOC(=O)c1sc(Br)c(C#N)c1Br>>N#Cc1c(Br)sc(C(=O)O)c1Br -US20130004427A1,1,COC(=O)CBr.COc1cc(O)ccc1N=Nc1ccc(CO)cc1>>COC(=O)COc1ccc(N=Nc2ccc(CO)cc2)c(OC)c1 -US05843937,6,COC(=O)C=Cc1cc2cc(NC(=O)c3cc4ccccc4o3)ccc2[nH]1>>O=C(O)C=Cc1cc2cc(NC(=O)c3cc4ccccc4o3)ccc2[nH]1 -US07985861B2,4,CCOC(=O)C(NC(=O)NNC(=O)c1ccccc1)C(C)C>>CCOC(=O)C(Nc1nnc(-c2ccccc2)o1)C(C)C -US20100130737A1,6,COC(=O)[C@H](Cc1ccc(OCc2ccsc2)cc1)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](N)Cc1ccc(OCc2ccsc2)cc1 -US20100120775A1,1,CC(C)c1onc(COC2CCCC2)c1CO.COC(=O)c1ccc2cc(-c3ccc(O)cc3)ccc2n1>>COC(=O)c1ccc2cc(-c3ccc(OCc4c(COC5CCCC5)noc4C(C)C)cc3)ccc2n1 -US04761404,6,CC(C)(C)OC(=O)NCCCO[P+]([O-])=C(O)C[N+](C)(C)C>>C[N+](C)(C)CC(O)=[P+]([O-])OCCCN -US06531502B1,3,COc1ccc2c(c1)NC(=O)C2.O=Cc1[nH]c2c(c1CCC(=O)O)CCCC2>>COc1ccc2c(c1)NC(=O)C2=Cc1[nH]c2c(c1CCC(=O)O)CCCC2 -US20040009995A1,6,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2COCCC(=O)O)c1>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2COCCC(=O)O)c1 -US05703243,1,CS(=O)(=O)OC[C@@H]1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1C[C@@H]1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1 -US08163728B2,7,CCCCc1noc(C=O)c1COc1cc(C(=O)OC)n(C)n1>>CCCCc1noc(CO)c1COc1cc(C(=O)OC)n(C)n1 -US06936611B2,6,CC(C)(C)[Si](C)(C)OCCc1ccnc(C#N)c1>>N#Cc1cc(CCO)ccn1 -US20090012077A1,4,NNc1ccccc1C(F)(F)F.O=C1CCNCC1>>FC(F)(F)c1cccc2c3c([nH]c12)CCNC3 -US20100120717A1,1,COc1ccc(Cn2cc(Cl)nc(Cl)c2=O)cc1.Nc1ncc(Cl)cc1Br>>COc1ccc(Cn2cc(Cl)nc(Nc3ncc(Cl)cc3Br)c2=O)cc1 -US06969711B2,7,O=[N+]([O-])c1cccc(C(F)(F)F)c1O>>Nc1cccc(C(F)(F)F)c1O -US04304780,2,CN(C)Cc1ccc(CSCCN=C=S)o1.CN(C)Cc1cccc(OCCCN)c1>>CN(C)Cc1cccc(OCCCNC(=S)NCCSCc2ccc(CN(C)C)o2)c1 -US20140194476A1,6,O=c1cc(CNS(=O)(=O)c2ccccc2Cl)occ1OCc1ccccc1>>O=c1cc(CNS(=O)(=O)c2ccccc2Cl)occ1O -US04518597,1,CC(C)(C)c1cc(S)cc(C(C)(C)C)c1O.CC1(C)OC(=O)Nc2ccc(OCCCCCl)cc21>>CC(C)(C)c1cc(SCCCCOc2ccc3c(c2)C(C)(C)OC(=O)N3)cc(C(C)(C)C)c1O -US08080570B2,2,C#CCC(N)c1ccccc1.O=C=NCCCl>>C#CCC(NC(=O)NCCCl)c1ccccc1 -US20150183847A1,2,O=C(O)/C=C\C(=O)NCCCCCCCCCCCCCCCCCC(=O)O>>O=C(O)CCCCCCCCCCCCCCCCCN1C(=O)C=CC1=O -US05538976,1,FC(F)(F)c1ccc(CBr)cc1.O=[N+]([O-])c1ccc(Nc2cncnc2)cc1>>O=[N+]([O-])c1ccc(N(Cc2ccc(C(F)(F)F)cc2)c2cncnc2)cc1 -US08501732B2,2,NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O.O=C(Cl)c1cccc(F)c1F>>O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1cccc(F)c1F -US08598173B2,1,C[O-].Cc1ccc2nc(Cl)c(N)nc2c1>>COc1nc2ccc(C)cc2nc1N -US20100160279A1,6,COc1cccc(SC2CN(C(C)(C)CCC(C(N)=O)(c3ccccc3)c3ccccc3)C2)c1>>CC(C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)N1CC(Sc2cccc(O)c2)C1 -US20060004011A1,2,NCCCN1CCOCC1.O=C(O)c1ccc2[nH]c(-c3nc4ccccc4[nH]c3=O)cc2c1>>O=C(NCCCN1CCOCC1)c1ccc2[nH]c(-c3nc4ccccc4[nH]c3=O)cc2c1 -US06245761B1,2,CNC.O=C(O)c1cc(Br)ccc1F>>CN(C)C(=O)c1cc(Br)ccc1F -US20130231402A1,2,CCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O>>CCCCCCCCCCCC(=O)N[C@H]1CCC(=O)OC1=O -US20140135360A1,3,CC(C)(C)c1cc(Br)c(O)c(C=O)c1.OB(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(C)(C)c1cc(C=O)c(O)c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 -US20150284385A1,6,CC(C)(C)OC(=O)N[C@H]1Cc2c(nc3cc(-c4nnco4)ccn23)C[C@@H]1c1cc(F)c(F)cc1F>>N[C@H]1Cc2c(nc3cc(-c4nnco4)ccn23)C[C@@H]1c1cc(F)c(F)cc1F -US05710139,10,Cc1cc2ccccc2nc1C.O=C1CCC(=O)N1Br>>Cc1nc2ccccc2cc1CBr -US20080194535A1,2,C=CC[C@H](NC)C(=O)OC.O=C(O)CCCC(F)(F)F>>C=CC[C@@H](C(=O)OC)N(C)C(=O)CCCC(F)(F)F -US03936468,8,O=c1[nH]c2ccccc2n1C1CCN(CCCC(O)c2ccc(F)cc2)CC1>>O=C(CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1 -US20070299102A1,7,Cc1c(Cl)c([N+](=O)[O-])cc2c1NC(=O)C2(c1ccc(O)cc1)c1ccc(O)cc1>>Cc1c(Cl)c(N)cc2c1NC(=O)C2(c1ccc(O)cc1)c1ccc(O)cc1 -US08299267B2,1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN.CC(C)(O)c1cccc(C=O)c1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1cccc(C(C)(C)O)c1 -US20060264444A1,1,COC(=O)c1ccc(OCC(C)=O)cc1.NNc1ccc(F)cc1>>COC(=O)c1ccc(OC/C(C)=N\Nc2ccc(F)cc2)cc1 -US05760035,3,CN(C)CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCN(CCOc2ccccc2)CC1>>CN(C)CC=C1CCN(CCOc2ccccc2)CC1 -US06583296B2,9,CN1CCC(=O)c2c(ccn2CCCCCl)S1(=O)=O.NO>>CN1CCC(=NO)c2c(ccn2CCCCCl)S1(=O)=O -US20090203695A1,2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.OCC1CCN(Cc2ccccc2)CC1>>O=C(OCC1CCN(Cc2ccccc2)CC1)Oc1ccc([N+](=O)[O-])cc1 -US08637559B2,1,CC(C)Br.Cc1cccnc1C(=O)NCc1coc(-c2ccc(OC(F)F)c(O)c2)n1>>Cc1cccnc1C(=O)NCc1coc(-c2ccc(OC(F)F)c(OC(C)C)c2)n1 -US08440830B2,3,CC(C)(C)OC(=O)Nc1ccc(Br)cc1[N+](=O)[O-].OB(O)c1ccsc1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccsc2)cc1[N+](=O)[O-] -US20130005707A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CNc1nc2ccc(Br)cc2[nH]1>>CNc1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2[nH]1 -US20150102321A1,1,Ic1cccc2c1oc1c(C3CCCCC3)cccc12.Nc1ccccc1-c1ccccc1>>c1ccc(-c2ccccc2Nc2cccc3c2oc2c(C4CCCCC4)cccc23)cc1 -US05563142,6,COc1c(C)cc(CCl)cc1C>>Cc1cc(CCl)cc(C)c1O -US06271223B1,1,Cn1cc2c(c1)S(=O)(=O)NCCC2=O.Fc1ccc(N2CCN(CCCCl)CC2)cc1>>Cn1cc2c(c1)S(=O)(=O)N(CCCN1CCN(c3ccc(F)cc3)CC1)CCC2=O -US05817678,6,CCOC(=O)[C@H]1CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC[C@H](C(=O)O)C1 -US20110028390A1,6,COC(=O)c1ccc2c(cnn2C)c1>>Cn1ncc2cc(C(=O)O)ccc21 -US06080785,1,NCCNCCN.O=Cc1ccccc1>>NCCNCCNCc1ccccc1 -US20090042929A1,2,NCc1cccs1.O=C=NC12CC3CC(CC(C3)C1)C2>>O=C(NCc1cccs1)NC12CC3CC(CC(C3)C1)C2 -US20140288071A1,3,COc1ncnc2c(Br)csc12.OB(O)C1CC1>>COc1ncnc2c(C3CC3)csc12 -US09145414B2,6,CCOC(=O)c1cc(OC(C)=O)c2ccsc2c1>>CCOC(=O)c1cc(O)c2ccsc2c1 -US06355806B1,7,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(=O)CCC3(C)C)nc1>>CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(O)CCC3(C)C)nc1 -US20080305169A1,2,CC1Cc2ccccc2N1.O=C(Cl)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1>>CC1Cc2ccccc2N1C(=O)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1 -US06562849B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(CCO)cc1>>CC(C)(C)OC(=O)Nc1ccc(CCO)cc1 -US07189847B2,7,COC(=O)[C@H](C)Nc1ccc(F)c(F)c1F>>C[C@@H](CO)Nc1ccc(F)c(F)c1F -US08435980B2,2,COc1cnc2[nH]cc(-c3cc(Cl)nc(NC4CCC(CC5CCC(N)CC5)CC4)c3)c2c1.O=C(O)C1CC1>>COc1cnc2[nH]cc(-c3cc(Cl)nc(NC4CCC(CC5CCC(NC(=O)C6CC6)CC5)CC4)c3)c2c1 -US08183200B1,7,CC1=CCC(C=O)(C2C3CCC(C3)C2(C)C)CC1>>CC1=CCC(CO)(C2C3CCC(C3)C2(C)C)CC1 -US20130150416A1,2,Nc1ccc([N+](=O)[O-])cc1Cl.O=C(O)c1ccccc1O>>O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1ccccc1O -US20040186091A1,1,C=O.Clc1ccc2c(c1)CNCc1nnc(C3CCN(c4ncccn4)CC3)n1-2>>CN1Cc2cc(Cl)ccc2-n2c(nnc2C2CCN(c3ncccn3)CC2)C1 -US04492794,4,CCOC(=O)C(=O)CBr.N=C(N)NC(N)=S>>CCOC(=O)c1csc(NC(=N)N)n1 -US06797823B1,1,BrCCBr.CCNC(=O)Nc1cc(C)c(Oc2ccnc3cc(O)c(OC)cc23)cc1C>>CCNC(=O)Nc1cc(C)c(Oc2ccnc3cc(OCCBr)c(OC)cc23)cc1C -US04615966,6,CNS(=O)(=O)c1cc2c(cc1Br)CCN2C(C)=O>>CNS(=O)(=O)c1cc2c(cc1Br)CCN2 -US07135487B2,4,CC(=O)CCC(C)=O.Nc1ccc(Br)cc1>>Cc1ccc(C)n1-c1ccc(Br)cc1 -US06413938B1,4,CC(C)N=C=S.N#Cc1ccc(N)c(N)c1>>CC(C)Nc1nc2cc(C#N)ccc2[nH]1 -US20110178117A1,4,C=CCCCCCCO.OO>>OCCCCCCC1CO1 -US20060189629A1,7,COC(=O)C1CC(Oc2ccc(-n3cnc4cc(C(=O)NCc5cccnc5)ccc43)cc2)C1>>O=C(NCc1cccnc1)c1ccc2c(c1)ncn2-c1ccc(OC2CC(CO)C2)cc1 -US20080194647A1,3,C#Cc1ccc(F)cc1.O=S(=O)(Oc1cncc(Cl)c1)C(F)(F)F>>Fc1ccc(C#Cc2cncc(Cl)c2)cc1 -US20120077812A1,6,CC(C)(C)OC(=O)N1CCC(COc2ccc(-c3ccc(S(C)(=O)=O)cc3)cn2)CC1>>CS(=O)(=O)c1ccc(-c2ccc(OCC3CCNCC3)nc2)cc1 -US08153814B2,1,CC(C)(C)n1ncc(-c2cc(Cl)ccc2O)c1NC(=O)C(F)(F)F.COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(F)c(C#N)c2)c(OC)c1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(Oc3ccc(Cl)cc3-c3cnn(C(C)(C)C)c3NC(=O)C(F)(F)F)c(C#N)c2)c(OC)c1 -US07863332B2,3,CCCCOc1cc(/C=C/C(=O)OC)ccc1I.CNc1cccc(B2OC(C)(C)C(C)(C)O2)c1>>CCCCOc1cc(/C=C/C(=O)OC)ccc1-c1cccc(NC)c1 -US20120142665A1,6,COC(=O)c1cc2nc(-c3ccccc3)nn2cc1C>>Cc1cn2nc(-c3ccccc3)nc2cc1C(=O)O -US08138177B2,2,CC[C@H](C)[C@H](NC(=O)n1c(=O)n(CCN2CCOCC2)c2ccccc21)C(=O)O.CNC>>CC[C@H](C)[C@H](NC(=O)n1c(=O)n(CCN2CCOCC2)c2ccccc21)C(=O)N(C)C -US20130040933A1,3,Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(Cl)cnc32)cc1.O=C(Cn1ccc2ncc(Cl)nc21)NCC(F)(F)F>>Cc1ccc(S(=O)(=O)n2cc(-c3cnc4ccn(CC(=O)NCC(F)(F)F)c4n3)c3cc(Cl)cnc32)cc1 -US06924292B2,3,CCCCOc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(Br)c1)=NC(C)(C)C2.OB(O)c1ccncc1>>CCCCOc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(-c3ccncc3)c1)=NC(C)(C)C2 -US20130119312A1,3,CCc1ccc(-c2c(F)cc(B(O)O)cc2F)cc1.CCc1ccc(Br)s1>>CCc1ccc(-c2c(F)cc(-c3ccc(CC)s3)cc2F)cc1 -US05025031,2,CNS(=O)(=O)Cl.OCCOc1ccccc1>>CNS(=O)(=O)OCCOc1ccccc1 -US20090182029A1,6,COC(=O)CNC(=O)c1c(C)[nH]c(C=NN=C2C(=O)Nc3ccc(F)cc32)c1C>>Cc1[nH]c(C=NN=C2C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NCC(=O)O -US20110251247A1,2,CC(=O)Cl.NCc1cc(C2=NOC(c3cc(Cl)c(F)c(Cl)c3)(C(F)(F)F)C2)ccc1F>>CC(=O)NCc1cc(C2=NOC(c3cc(Cl)c(F)c(Cl)c3)(C(F)(F)F)C2)ccc1F -US20080070864A1,1,CC(c1nc2ccccc2c(=O)n1-c1ccc(O)cc1)N(C)S(=O)(=O)c1ccc(C(C)(C)C)cc1.OCc1ccccc1>>CC(c1nc2ccccc2c(=O)n1-c1ccc(OCc2ccccc2)cc1)N(C)S(=O)(=O)c1ccc(C(C)(C)C)cc1 -US20120101124A1,3,CCOC(=O)CC[Zn]Br.Cc1ccc(S(=O)(=O)n2ccc3c(C#N)ccc(Br)c32)cc1>>CCOC(=O)CCc1ccc(C#N)c2ccn(S(=O)(=O)c3ccc(C)cc3)c12 -US05714498,1,C1=C(c2cc3ccccc3s2)CCNC1.ClCc1nc2ccccc2[nH]1>>C1=C(c2cc3ccccc3s2)CCN(Cc2nc3ccccc3[nH]2)C1 -US20140323480A1,1,C[O-].Cc1c(Cn2cnc3c(Cl)cc(Cl)nc32)cccc1C(F)(F)F>>COc1cc(Cl)nc2c1ncn2Cc1cccc(C(F)(F)F)c1C -US04331807,2,Nc1ccnnc1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1ccnnc1 -US20030153558A1,7,CCOC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)n2c1CCC2>>OCc1c(-c2ccc(F)cc2)c(-c2ccncc2)n2c1CCC2 -US20090239865A1,9,Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2Br)n1.[C-]#N>>Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2C#N)n1 -US20110217311A1,9,Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3OC3CCCC3)c12.N>>Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3OC3CCCC3)c12 -US20140315888A1,6,Cc1cc2c3cc(Br)cnc3nc(N3CC(N(C)C(=O)OC(C)(C)C)C3)n2n1>>CNC1CN(c2nc3ncc(Br)cc3c3cc(C)nn23)C1 -US07135475B2,2,CCCCn1c(N)c(NC(=O)Cc2ccc(N)cc2)c(=O)n(Cc2ccccc2F)c1=O.O=C(O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CCCCn1c(N)c(NC(=O)Cc2ccc(NC(=O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)cc2)c(=O)n(Cc2ccccc2F)c1=O -US06087357,1,CS(=O)(=O)OCCCN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2c[nH]c3ccccc23)C1.c1ccc2c(c1)CCC21CCNCC1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(CCCN2CCC3(CCc4ccccc43)CC2)C[C@H]1Cc1c[nH]c2ccccc12 -US08519135B2,1,CCc1cc(S(=O)(=O)Nc2cc(Cl)cnc2Br)ccc1Cl.COCCl>>CCc1cc(S(=O)(=O)N(COC)c2cc(Cl)cnc2Br)ccc1Cl -US08268822B2,2,CC(C)(C)OC(=O)N1CCC(NCc2cccc(-c3ccnc(Cl)n3)c2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(N(Cc2cccc(-c3ccnc(Cl)n3)c2)S(C)(=O)=O)CC1 -US20040087626A1,6,COc1ccc2oc(Nc3ccc(Br)cc3)nc2c1>>Oc1ccc2oc(Nc3ccc(Br)cc3)nc2c1 -US20130096144A1,3,Cn1nccc1B1OC(C)(C)C(C)(C)O1.O=C1c2ccccc2C(=O)N1C[C@H](Cc1cccc(F)c1)N1Cc2cc(Br)ccc2C1=O>>Cn1nccc1-c1ccc2c(c1)CN([C@@H](Cc1cccc(F)c1)CN1C(=O)c3ccccc3C1=O)C2=O -US20020119983A1,1,O=CCCc1cc(-c2cccc(Oc3ccccc3)c2)no1.c1ccc(N2CCNCC2)cc1>>c1ccc(Oc2cccc(-c3cc(CCCN4CCN(c5ccccc5)CC4)on3)c2)cc1 -US20110092547A1,6,COC(=O)[C@@H]1CC[C@@H](Oc2ccc(NC(=O)c3nnc(Nc4ccc(F)c(F)c4)o3)cn2)C1>>O=C(Nc1ccc(O[C@@H]2CC[C@@H](C(=O)O)C2)nc1)c1nnc(Nc2ccc(F)c(F)c2)o1 -US20150087664A1,2,COc1ccc([C@H](N)c2cnn(C)c2)cc1F.O=C(O)c1cc(F)c2cnc(NCC3CC3)nc2c1>>COc1ccc([C@H](NC(=O)c2cc(F)c3cnc(NCC4CC4)nc3c2)c2cnn(C)c2)cc1F -US06432950B1,1,FC(F)(F)c1cc2c(Cl)nc(-c3ccccn3)nc2s1.NCc1ccc(F)cc1>>Fc1ccc(CNc2nc(-c3ccccn3)nc3sc(C(F)(F)F)cc23)cc1 -US03931177,1,Cc1ccc(C2=NNC(=O)CC2)cc1O.ClCC1CO1>>Cc1ccc(C2=NNC(=O)CC2)cc1OCC1CO1 -US20150065482A1,7,COC(=O)c1cc([N+](=O)[O-])n[nH]1>>COC(=O)c1cc(N)n[nH]1 -US20100041891A1,3,CCOC(=O)c1cccc(B(O)O)c1.OCc1cc2c(F)ccc(Br)c2s1>>CCOC(=O)c1cccc(-c2ccc(F)c3cc(CO)sc23)c1 -US20060074237A1,2,CCOCc1ccc(N)nc1C.O=S(=O)(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCOCc1ccc(NS(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)nc1C -US04634710,1,CC1(C)C(=O)C(C)(C)c2cc3[nH]c(S)nc3cc21.COc1c(C)cnc(CCl)c1C>>COc1c(C)cnc(CSc2nc3cc4c(cc3[nH]2)C(C)(C)C(=O)C4(C)C)c1C -US06114358,9,N.O=C(Cl)c1cc(CCl)on1>>NC(=O)c1cc(CCl)on1 -US08344027B2,2,CN(C)C[C@H](N)CC(=O)OCc1ccccc1.O=C(O)CCCCCc1ccccc1>>CN(C)C[C@@H](CC(=O)OCc1ccccc1)NC(=O)CCCCCc1ccccc1 -US06211198B1,3,CCCCCC(=O)CC(=O)OCCC#N.O=Cc1ccc([N+](=O)[O-])cc1>>CCCCCC(=O)C(=Cc1ccc([N+](=O)[O-])cc1)C(=O)OCCC#N -US20080312276A1,2,CC(C)(N=C=O)c1ccccc1.CCCCC1=NNC(C)(C)C1c1ccccc1>>CCCCC1=NN(C(=O)NC(C)(C)c2ccccc2)C(C)(C)C1c1ccccc1 -US04118587,1,BrC/C=C/CBr.Nc1cc(C(=O)O)cc(S(N)(=O)=O)c1Oc1ccccc1>>NS(=O)(=O)c1cc(C(=O)O)cc(NC/C=C/CBr)c1Oc1ccccc1 -US06198007B1,1,O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1.OCCO>>O=[N+]([O-])c1ccc(OCCO)c([N+](=O)[O-])c1 -US06916822B2,8,CCN(CC)C(=O)c1ccc(CO)cc1>>CCN(CC)C(=O)c1ccc(C=O)cc1 -US08003649B2,1,Clc1ccccc1N1CCNCC1.FC(F)(F)c1nnc2ccc(Cl)nn12>>FC(F)(F)c1nnc2ccc(N3CCN(c4ccccc4Cl)CC3)nn12 -US20110130398A1,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)cc(F)c12.COc1cc(C#N)ccc1N>>COc1cc(C#N)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(Cl)cc(F)c32)C1c1cccc(Cl)c1F -US20090054405A1,3,CC(=O)Nc1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2s1.Cc1ccc(S(=O)(=O)Nc2cncc(Br)c2)cc1>>CC(=O)Nc1nc2ccc(-c3cncc(NS(=O)(=O)c4ccc(C)cc4)c3)cc2s1 -US20120264733A1,9,CC(C)CN(C(=O)c1nc2ccccc2n1CCC(N)=O)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1>>CC(C)CN(C(=O)c1nc2ccccc2n1CCC#N)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1 -US20050026929A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1ccc(C(=O)O)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)NCc1ccc(C(=O)O)cc1[N+](=O)[O-] -US05932606,9,CC(C)(C)OC(=O)N1CCCC(N=[N+]=[N-])C1>>CC(C)(C)OC(=O)N1CCCC(N)C1 -US20150225400A1,3,CN1CC[C@@]2(CC[C@H](c3cc(Br)ccn3)N2)C1=O.OB(O)c1cc(O)ccc1F>>CN1CC[C@@]2(CC[C@H](c3cc(-c4cc(O)ccc4F)ccn3)N2)C1=O -US08063066B2,1,Cc1c(O)c(=O)c2c(F)cc(F)cc2n1C1CC1.Nc1ccc(I)cc1F>>Cc1c(O)c(=O)c2c(Nc3ccc(I)cc3F)cc(F)cc2n1C1CC1 -US20100041905A1,2,CC(=O)OC(C)=O.CC(O)(CO)COc1cc(O)ccc1N>>CC(=O)Nc1ccc(O)cc1OCC(C)(O)CO -US07491819B1,9,O=C(c1cc(F)ccc1CBr)N1CCOCC1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc(F)cc1C(=O)N1CCOCC1 -US06340761B1,3,CC(C)(Br)c1ccc(C(=O)CCCCl)cc1.C[Si](C)(C)C#N>>CC(C)(C#N)c1ccc(C(=O)CCCCl)cc1 -US08476253B2,7,CN(CCCN(C)C(=O)c1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C>>CN(CCCN(C)C(=O)c1ccc(N)cc1)C(=O)OC(C)(C)C -US05344843,1,BrCCCc1ccccc1.COC(=O)C(=O)c1ccc(O)cc1>>COC(=O)C(=O)c1ccc(OCCCc2ccccc2)cc1 -US20070010511A1,1,COCCCN1C(=O)C(C)(C)c2ccc(CBr)cc21.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1>>COCCCN1C(=O)C(C)(C)c2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCCOCc4ccccc4OC)cc3)cc21 -US20130253197A1,6,COC(OC)c1c(OC(F)F)ccc(F)c1Cl>>O=Cc1c(OC(F)F)ccc(F)c1Cl -US20110294781A1,1,NNc1cc(N2CCOCC2)n2nc(-c3ccccc3)cc2n1.O=Cc1cccc2[nH]ccc12>>C(=NNc1cc(N2CCOCC2)n2nc(-c3ccccc3)cc2n1)c1cccc2[nH]ccc12 -US20080176832A1,1,CC(C)C=O.CN(C)C(=O)c1ccc(-n2cc3c(n2)CCNCC3)cc1>>CC(C)CN1CCc2cn(-c3ccc(C(=O)N(C)C)cc3)nc2CC1 -US05885979,2,O=C(O)CNC[C@H]1O[C@H](c2ccccc2Cl)c2cc(Cl)ccc2N(Cc2ccccc2)C1=O.O=C(OC(=O)c1ccccc1)c1ccccc1>>O=C(O)CN(C[C@H]1O[C@H](c2ccccc2Cl)c2cc(Cl)ccc2N(Cc2ccccc2)C1=O)C(=O)c1ccccc1 -US07820823B2,6,CC(C)(C)OC(=O)N1CCN(c2ccc(N3C[C@H](CNC(N)=S)OC3=O)cc2F)CC1>>NC(=S)NC[C@H]1CN(c2ccc(N3CCNCC3)c(F)c2)C(=O)O1 -US20040059130A1,6,CCc1c(C(=O)C(N)=O)c2c(OCC(=O)OCc3ccccc3)c3ccccc3cc2n1Cc1ccccc1>>CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)c3ccccc3cc2n1Cc1ccccc1 -US06265575B1,1,ClCCN1CCCC1.OCc1cc(Br)ccc1O>>OCc1cc(Br)ccc1OCCN1CCCC1 -US08362003B2,5,COC(=O)CC(=O)CC(=O)OC.OCCO>>COC(=O)CC1(CC(=O)OC)OCCO1 -US03953497,2,CCO.CNC(=O)c1c(I)c(NC(=O)COC)c(I)c(C(=O)Cl)c1I>>CCOC(=O)c1c(I)c(NC(=O)COC)c(I)c(C(=O)NC)c1I -US20020107269A1,2,COC(=O)Cl.Cc1ccc2c(c1)nc(-c1cc(N)ccc1Cl)n2C>>COC(=O)Nc1ccc(Cl)c(-c2nc3cc(C)ccc3n2C)c1 -US05644061,7,CCOC(=O)C(C)(C)c1ccc(C(=O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1>>CCOC(=O)C(C)(C)c1ccc([C@@H](O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 -US20140336108A1,2,CCOC(CCN)OCC.Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)O)sc34)cc2F)c1>>CCOC(CCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1)OCC -US20100286120A1,6,CCCCOc1ccc2c(n1)OCCN(C(=O)OC(C)(C)C)C2>>CCCCOc1ccc2c(n1)OCCNC2 -US20050245531A1,3,Clc1ccc(O[C@@H]2CN3CCC2CC3)nn1.OB(O)c1ccc2[nH]ccc2c1>>c1cc2cc(-c3ccc(O[C@@H]4CN5CCC4CC5)nn3)ccc2[nH]1 -US07678815B2,2,Cc1cc(C(=O)O)c(NC(=O)OC(C)(C)C)s1.Nc1cccc(Cl)c1>>Cc1cc(C(=O)Nc2cccc(Cl)c2)c(NC(=O)OC(C)(C)C)s1 -US06054457,8,COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCCO)ccc1NC(=O)c1ccccc1OCCCNC(=O)OC(C)(C)C>>COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC=O)ccc1NC(=O)c1ccccc1OCCCNC(=O)OC(C)(C)C -US20140018345A1,3,CCCC[Sn](CCCC)(CCCC)c1ccnn1-c1ccc(C#N)cc1.Cc1c(Br)cn2ccnc2c1-c1cccc(C(F)(F)F)c1>>Cc1c(-c2ccnn2-c2ccc(C#N)cc2)cn2ccnc2c1-c1cccc(C(F)(F)F)c1 -US20060094768A1,3,C=C(C)Br.O=Cc1sc(-c2ccc(C(F)(F)F)cc2)cc1B(O)O>>C=C(C)c1cc(-c2ccc(C(F)(F)F)cc2)sc1C=O -US20080132477A1,2,C=CCOc1cc(O)cc(C(=O)O)c1.CC(=O)Cl>>C=CCOc1cc(OC(C)=O)cc(C(=O)O)c1 -US07407961B2,1,CC(C)n1cc(-c2nc(Br)c(N)nc2-c2ccccc2)ccc1=O.Oc1ccccc1>>CC(C)n1cc(-c2nc(Oc3ccccc3)c(N)nc2-c2ccccc2)ccc1=O -US04861880,2,Fc1cccc(Nc2ccccc2)c1.O=C(Cl)CCl>>O=C(CCl)N(c1ccccc1)c1cccc(F)c1 -US08198454B2,1,CCn1cc(CN(C(=O)C2CCCc3ccc(O)cc32)c2ccc(C(C)C)cc2)cn1.CN(C)CCCl>>CCn1cc(CN(C(=O)C2CCCc3ccc(OCCN(C)C)cc32)c2ccc(C(C)C)cc2)cn1 -US09126981B2,2,CCOC(OCC)[C@H](C)NCc1cccc2cccnc12.Cc1cc(O)cc(C)c1C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>CCOC(OCC)[C@H](C)N(Cc1cccc2cccnc12)C(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)OCC1c2ccccc2-c2ccccc21 -US04645678,2,N[C@@H](CC(=O)O)C(=O)O.O=C=Nc1ccc([N+](=O)[O-])cc1>>O=C(O)C[C@H](NC(=O)Nc1ccc([N+](=O)[O-])cc1)C(=O)O -US09120749B2,3,CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(N2CCC(N(C)C(=O)OC(C)(C)C)C2)nc1.CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C>>CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCC(N(C)C(=O)OC(C)(C)C)C2)nc1 -US08030327B2,8,Cc1c(-c2cnc3ccccn23)sc(C(=O)O)c1O[C@H](C)c1ccc(CO)cc1Cl>>Cc1c(-c2cnc3ccccn23)sc(C(=O)O)c1O[C@H](C)c1ccc(C=O)cc1Cl -US20060281789A1,3,COc1cc(C=O)ccc1OCCN1CCOCC1.c1ccc([P+](Cc2n[nH]c3ccccc23)(c2ccccc2)c2ccccc2)cc1>>COc1cc(/C=C/c2n[nH]c3ccccc23)ccc1OCCN1CCOCC1 -US06984649B1,8,COC(=O)C1CCCC(CO)C1>>COC(=O)C1CCCC(C=O)C1 -US20090099180A1,3,O=C1N(Cc2c(Cl)cc(Br)cc2Cl)CCC12CCCCC2.OB(O)c1ccc(F)cc1>>O=C1N(Cc2c(Cl)cc(-c3ccc(F)cc3)cc2Cl)CCC12CCCCC2 -US04960758,6,COc1ccccc1C(=O)c1cccc(C#N)c1>>N#Cc1cccc(C(=O)c2ccccc2O)c1 -US20120035214A1,7,COC(=O)c1ccccc1-c1noc([C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(F)c(F)c2)c1Br>>CC(C)(C)OC(=O)N1CC[C@](O)(c2ccc(F)c(F)c2)[C@@H](c2onc(-c3ccccc3CO)c2Br)C1 -US20120220563A1,6,CCc1ccc(C2CC(C(=O)OC)CN(C(=O)N3CCSCC3)C2)cc1F>>CCc1ccc(C2CC(C(=O)O)CN(C(=O)N3CCSCC3)C2)cc1F -US20060148805A1,2,CCNC1CCCCC1.COc1ccc2nc(C(=O)C(C)(C)C)n(CC(=O)O)c2c1>>CCN(C(=O)Cn1c(C(=O)C(C)(C)C)nc2ccc(OC)cc21)C1CCCCC1 -US04523020,1,CCOC(=O)C(Br)CC.Cc1c(O)cccc1[N+](=O)[O-]>>CCOC(=O)C(CC)Oc1cccc([N+](=O)[O-])c1C -US20060122248A1,6,CC(=O)Nc1c(C)ccc(C(=O)O)c1[N+](=O)[O-]>>Cc1ccc(C(=O)O)c([N+](=O)[O-])c1N -US05998452,6,CCOC(=O)CC1SC(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)N(CCCN(C)CCOc2ccc3c(c2)OCO3)C1=O>>CN(CCCN1C(=O)C(CC(=O)O)SC1c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CCOc1ccc2c(c1)OCO2 -US05166390,2,CC(=O)S/C=C\C(=O)Cl.NC1CCCCCCCCCCC1>>CC(=O)S/C=C\C(=O)NC1CCCCCCCCCCC1 -US20050065143A1,6,COC(=O)c1ccccc1C(=O)N1CCN(c2ccc(C(=O)NCCC3CC3)nn2)CC1>>O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3ccccc3C(=O)O)CC2)nn1 -US04394515,1,C=[N+]=[N-].O=C(O)c1ccc2c(c1)Sc1ccccc1CC2O>>COC(=O)c1ccc2c(c1)Sc1ccccc1CC2O -US04829079,2,O=C1CCC(OCc2ccccc2)N1.O=S(=O)(Cl)c1ccccc1>>O=C1CCC(OCc2ccccc2)N1S(=O)(=O)c1ccccc1 -US20150111892A1,2,CCCCCCN=C=O.Cc1c[nH]c(=O)n(CC2CC2)c1=O>>CCCCCCNC(=O)n1cc(C)c(=O)n(CC2CC2)c1=O -US20080119486A1,1,Brc1ccc(-c2ncco2)cc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3ncco3)cc2)CC1 -US08569522B2,2,CC(C)(C)OC(=O)NCCc1ccc(CO)cc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NCCc1ccc(COS(C)(=O)=O)cc1 -US20140107126A1,3,Cc1nc(Br)n2c1c(C)nc1scnc12.NC(=O)c1cccc(B(O)O)c1>>Cc1nc(-c2cccc(C(N)=O)c2)n2c1c(C)nc1scnc12 -US20140194431A1,6,CC(C)N1CCn2c(CC3(c4ccc(Cl)c(Cl)c4)CCCC3)nc(=O)c(OCc3ccccc3)c2C1=O>>CC(C)N1CCn2c(CC3(c4ccc(Cl)c(Cl)c4)CCCC3)nc(=O)c(O)c2C1=O -US06436929B1,1,CC1(C)OC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21.CI>>Cn1c(C#N)ccc1-c1ccc2c(c1)C(C)(C)OC(=O)N2 -US06545161B2,1,CC(C)I.Nc1c(O)c(Cl)cc(F)c1-n1nnn(CCCF)c1=O>>CC(C)Oc1c(Cl)cc(F)c(-n2nnn(CCCF)c2=O)c1N -US20110275673A1,6,CC(C)CCCCCCc1ccc(NC(=O)OC(C)(C)C)cc1>>CC(C)CCCCCCc1ccc(N)cc1 -US20090227560A1,6,COC(=O)c1ncn([C@H]2CCCC[C@@H]2OCc2ccccc2)c1-c1ccccc1>>O=C(O)c1ncn([C@H]2CCCC[C@@H]2OCc2ccccc2)c1-c1ccccc1 -US07238716B2,1,Cc1oc(-c2ccccc2)nc1COc1cc(CO)on1.N#Cc1cccnc1Cl>>Cc1oc(-c2ccccc2)nc1COc1cc(COc2ncccc2C#N)on1 -US04555508,2,CCOC(=O)[C@@H]1CC(O)CN1.CCOC(=O)[C@H](CCc1ccccc1)N(C(=O)OCC(Cl)(Cl)Cl)[C@@H](C)C(=O)O>>CCOC(=O)[C@H](CCc1ccccc1)N(C(=O)OCC(Cl)(Cl)Cl)[C@@H](C)C(=O)N1CC(O)C[C@H]1C(=O)OCC -US20100267697A1,1,Nc1ccc(F)cc1.O=Cc1cnc(N2CCCCC2)nc1>>Fc1ccc(NCc2cnc(N3CCCCC3)nc2)cc1 -US20100216788A1,6,c1ccc(COc2cccc(-c3cnco3)c2)cc1>>Oc1cccc(-c2cnco2)c1 -US20140350011A1,4,NC(=O)[C@@H]1[C@H](Nc2c(Cl)cnc(N)c2N)[C@H]2C=C[C@@H]1C2.S=C=Nc1ccccc1>>NC(=O)[C@@H]1[C@H](Nc2c(Cl)cnc3[nH]c(Nc4ccccc4)nc23)[C@H]2C=C[C@@H]1C2 -US20100041891A1,8,CSCCNC(=O)c1cccc(-c2cccc3c(C)c(Cc4cccc(C(F)(F)F)c4)oc23)c1.O=C(OO)c1cccc(Cl)c1>>Cc1c(Cc2cccc(C(F)(F)F)c2)oc2c(-c3cccc(C(=O)NCCS(C)=O)c3)cccc12 -US20060074119A1,1,COC(=O)c1sc(-n2cnc3cc(Br)ccc32)cc1O.FC(F)(F)c1ccccc1CBr>>COC(=O)c1sc(-n2cnc3cc(Br)ccc32)cc1OCc1ccccc1C(F)(F)F -US20050143422A1,6,CC(C)[C@H](NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3nc4cc(C(F)(F)F)ccc4s3)cc2)cc1)C(=O)OC(C)(C)C>>CC(C)[C@H](NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3nc4cc(C(F)(F)F)ccc4s3)cc2)cc1)C(=O)O -US20050256132A1,2,COc1ccccc1C(c1ccnc2ccccc12)C(C)(C#N)C(=O)O.FC(F)(F)c1cccc(C2CC[NH2+]CC2)c1>>COc1ccccc1C(c1ccnc2ccccc12)C(C)(C#N)C(=O)N1CCC(c2cccc(C(F)(F)F)c2)CC1 -US20050192347A1,6,CC(C)(CO)CCCCN1C(=O)c2ccccc2C1=O>>CC(C)(CO)CCCCN -US06930104B2,1,COc1ccc(C(=O)N2CCC(O)c3ccccc32)cc1OC.c1ccc2c(c1)CCN2>>COc1ccc(C(=O)N2CCC(N3CCc4ccccc43)c3ccccc32)cc1OC -US08053440B2,4,COc1cc(N)c(C(N)=O)c(OC)c1.NC(=O)COc1ccc(C=O)cc1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCC(N)=O)cc3)nc2c1 -US20110224190A1,2,C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CN(C5CCNCC5)C4)c3)ncnc21.O=C=Nc1ccc(F)cc1C(F)(F)F>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CN(C5CCN(C(=O)Nc6ccc(F)cc6C(F)(F)F)CC5)C4)c3)ncnc21 -US20110312945A1,1,CCOC(=O)CBr.Cc1[nH]c2c(c1Sc1ccccc1)C(=O)CC(C)(C)C2>>CCOC(=O)Cn1c(C)c(Sc2ccccc2)c2c1CC(C)(C)CC2=O -US20150274777A1,2,CC(C)(C)OC(=O)NC1(C(=O)O)Cc2ccccc2C1.CNOC>>CON(C)C(=O)C1(NC(=O)OC(C)(C)C)Cc2ccccc2C1 -US20080070927A1,6,CC(=O)NC(COc1ccc2sc(C)nc2c1)CN1CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)NC(COc1ccc2sc(C)nc2c1)CN1CCNCC1 -US20120197027A1,1,COc1cc2c(Cl)ncnc2cc1OCCCn1cncn1.Nc1ccc2[nH]ccc2c1>>COc1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2cc1OCCCn1cncn1 -US20070254869A1,1,CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2cc(Cl)c(Br)cc21.CO>>COc1cc2c(cc1Cl)N(C(=O)OC(C)C)CCCC2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(C)=O -US20080027070A1,1,COc1ccc(Br)cc1.Nc1ncc([N+](=O)[O-])cn1>>COc1ccc(Nc2ncc([N+](=O)[O-])cn2)cc1 -US07887835B2,6,CCOC(=O)CCCCCCOc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(O)CCCCCCOc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20040167199A1,9,COc1ccc([C@@H](CC(=O)O)N2Cc3ccccc3C2=O)cc1OC.N>>COc1ccc(C(CC(N)=O)N2Cc3ccccc3C2=O)cc1OC -US20090012147A1,1,NC(=O)CBr.O=C1Nc2ccc(Cl)cc2C1(F)F>>NC(=O)CN1C(=O)C(F)(F)c2cc(Cl)ccc21 -US20150065705A1,7,O=C1COC(Cc2ccc(F)cc2)CN1>>Fc1ccc(CC2CNCCO2)cc1 -US20110201628A1,4,CSc1nc(Cl)c(C=O)c(Cl)n1.NNCCO>>CSc1nc(Cl)c2cnn(CCO)c2n1 -US05318966,7,COc1cccc2c1CC[C@H]1[C@@H]2CC(=O)N1CCCCC1CCCCC1>>COc1cccc2c1CC[C@H]1[C@@H]2CCN1CCCCC1CCCCC1 -US08293902B2,6,COc1ccc2[nH]ncc2c1>>Oc1ccc2[nH]ncc2c1 -US20100113773A1,7,CCOC(=O)[C@H]1CC[C@@H](c2ccc(F)cc2)N1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1[C@@H](CO)CC[C@H]1c1ccc(F)cc1 -US20110118221A1,1,CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N[C@@H]1c1ccc(C#N)cc1.COC(=O)CBr>>CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(CC(=O)OC)[C@@H]1c1ccc(C#N)cc1 -US20120258982A1,1,CC(=O)c1cccnc1Cl.Nc1ccccc1>>CC(=O)c1cccnc1Nc1ccccc1 -US07622486B2,1,Clc1cc(N2CCCC2)cc(Cl)n1.Nc1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(Nc2cc(N3CCCC3)cc(Cl)n2)cc1 -US20130109661A1,1,C1CCNC1.Fc1cccc(Nc2cc(Cl)nn3ccnc23)n1>>Clc1cc(Nc2cccc(N3CCCC3)n2)c2nccn2n1 -US20090286778A1,7,COc1ccc(Nc2nc(Cl)ncc2Cl)cc1/C=C/c1cncc(N)c1>>COc1ccc(Nc2nc(Cl)ncc2Cl)cc1CCc1cncc(N)c1 -US20100048537A1,6,CCOC(=O)CCN(C=O)Cc1cccs1>>O=CN(CCC(=O)O)Cc1cccs1 -US20030045581A1,1,NNC(=S)NC1CC2C=CC1C2.O=Cc1ccccc1C(F)(F)F>>FC(F)(F)c1ccccc1C=NNC(=S)NC1CC2C=CC1C2 -US20140011800A1,3,CO[C@H]1CN(C(=O)C2(C#N)CC2)C[C@H]1Nc1c(C(N)=O)cnn2cc(Br)cc12.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cc3c(N[C@@H]4CN(C(=O)C5(C#N)CC5)C[C@@H]4OC)c(C(N)=O)cnn3c2)cc1 -US20100234389A1,3,CC(C)(C)OC(=O)N1CCN(c2cncc(Cl)n2)CC1.OB(O)c1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCN(c2cncc(-c3ccc(F)cc3F)n2)CC1 -US20110288090A1,3,CC(C)(C)OC(=O)NCc1ccc(-c2nc3c(I)cnc(O)c3cc2-c2ccccc2)cc1.OB(O)c1ccco1>>CC(C)(C)OC(=O)NCc1ccc(-c2nc3c(-c4ccco4)cnc(O)c3cc2-c2ccccc2)cc1 -US06596719B1,2,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)ncnc1OCCN.CS(=O)(=O)Cl>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)ncnc1OCCNS(C)(=O)=O -US20040002511A1,7,O=[N+]([O-])c1cnn2ccccc12>>Nc1cnn2ccccc12 -US20060142247A1,2,CCN1C(=O)C(C)(C)c2cc3nc(-c4n[nH]c5ccc(C(=O)O)cc45)[nH]c3cc21.Nc1ccccc1>>CCN1C(=O)C(C)(C)c2cc3nc(-c4n[nH]c5ccc(C(=O)Nc6ccccc6)cc45)[nH]c3cc21 -US20040247523A1,6,COC(=O)C(Cc1ccccc1OCCCCCOc1cccc(-c2ccc(-c3ccc4c(c3)OCO4)cc2)n1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC(Cc1ccccc1OCCCCCOc1cccc(-c2ccc(-c3ccc4c(c3)OCO4)cc2)n1)C(=O)O -US06124281,2,CNc1ccccc1.O=C(O)c1n[nH]c2c(=O)[nH]c3cc(Cl)ccc3c(=O)c12>>CN(C(=O)c1n[nH]c2c(=O)[nH]c3cc(Cl)ccc3c(=O)c12)c1ccccc1 -US20080090815A1,2,CC(C)n1c(=O)oc2cc(N3C[C@H](CN)OC3=O)ccc21.O=C(Cl)c1ccc(Cl)s1>>CC(C)n1c(=O)oc2cc(N3C[C@H](CNC(=O)c4ccc(Cl)s4)OC3=O)ccc21 -US20060025421A1,1,Brc1ccc(Br)nc1.CC[O-]>>CCOc1ccc(Br)cn1 -US08026247B2,2,CCCCOC(=O)c1cc(Oc2ccc3c(C(=O)Nc4cccc(C(F)(F)F)c4)cccc3c2)ccn1.CN>>CNC(=O)c1cc(Oc2ccc3c(C(=O)Nc4cccc(C(F)(F)F)c4)cccc3c2)ccn1 -US09133168B2,2,CC1Cc2c(F)cccc2N1.Cn1c(CC(=O)[O-])nc(N2CCOCC2)cc1=O>>CC1Cc2c(F)cccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)n1C -US08501765B2,3,CCCC[Sn](CCCC)(CCCC)c1nccs1.N#Cc1cc2c(cn1)[nH]c1ncc(Br)cc12>>N#Cc1cc2c(cn1)[nH]c1ncc(-c3nccs3)cc12 -US08288549B2,1,NC(CO)C(=O)Nc1ccccc1.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1NC(CO)C(=O)Nc1ccccc1 -US20090163488A1,2,CCOC(=O)N=C=S.Cc1cccnc1C(=O)Nc1cccc(Oc2ccc(N)nc2)c1>>CCOC(=O)NC(=S)Nc1ccc(Oc2cccc(NC(=O)c3ncccc3C)c2)cn1 -US20050113379A1,6,COC[C@H](C)n1cc(C)c2nc(-c3ccc(C(C)C)nc3OC)c(OC)cc21>>COC[C@H](C)n1cc(C)c2nc(-c3ccc(C(C)C)nc3O)c(OC)cc21 -US05684002,7,CC(C)(C)c1cc([N+](=O)[O-])cc2c1OCC2(C)C>>CC(C)(C)c1cc(N)cc2c1OCC2(C)C -US20150183775A1,1,COC(=O)c1ccc(F)cc1O.COc1ccc(CBr)cc1>>COC(=O)c1ccc(F)cc1OCc1ccc(OC)cc1 -US20110130398A1,2,CC(C)(C)CC1NC(C(=O)O)C(c2cc(F)cc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12.COc1cc(C#N)ccc1N>>COc1cc(C#N)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cc(F)cc(Cl)c1 -US05232916,1,ClCc1ccc2ccccc2n1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCc2ccc3ccccc3n2)cc1 -US06339087B1,6,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>CC(C)[C@H](N)C(=O)N1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 -US06809199B2,6,COc1cc(-c2ccc(F)cc2F)c2ccc(=O)n(-c3c(Cl)cccc3Cl)c2c1>>O=c1ccc2c(-c3ccc(F)cc3F)cc(O)cc2n1-c1c(Cl)cccc1Cl -US07652058B2,2,CC(=O)OC(C)=O.Cc1cc(F)ccc1[C@@H]1[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC[C@@H]2CNC[C@H]21>>CC(=O)N1C[C@H]2CO[C@H](O[C@H](C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H](c3ccc(F)cc3C)[C@@H]2C1 -US08546359B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@](N)(CO)c1ccc2c(C(F)(F)F)c(OC3CCC(C4CCCC4)CC3)ccc2c1>>CC(C)(C)OC(=O)N[C@@](C)(CO)c1ccc2c(C(F)(F)F)c(OC3CCC(C4CCCC4)CC3)ccc2c1 -US04927836,2,COC(=O)COc1ccc(OCCNCC(O)COc2ccccc2)cc1.COCCN>>COCCNC(=O)COc1ccc(OCCNC[C@H](O)COc2ccccc2)cc1 -US20120142917A1,1,Cn1nnnc1S.O=C1C(Cl)=C/C(=N\S(=O)(=O)c2cccs2)c2ccccc21>>Cn1nnnc1SC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O -US20080015203A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc(N)n[nH]1>>Cc1cc(N)nn1C(=O)OC(C)(C)C -US04200648,1,Nc1ccc(Cl)c(Cl)c1.O=Cc1ccc(C(=O)O)cc1>>O=C(O)c1ccc(C=Nc2ccc(Cl)c(Cl)c2)cc1 -US08519135B2,1,COCCl.CON(C)C(=O)c1ncccc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>COCN(c1cccnc1C(=O)N(C)OC)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20050090509A1,1,O=C(O)Cc1ccc(O)cc1.O=C(c1cc2nccc(Cl)c2s1)N1CCC1>>O=C(O)Cc1ccc(Oc2ccnc3cc(C(=O)N4CCC4)sc23)cc1 -US20070185092A1,9,[N-]=[N+]=NCc1ccn(-c2ccc(I)cc2)n1>>NCc1ccn(-c2ccc(I)cc2)n1 -US20150181879A1,2,CC(C)(C)C(=O)Cl.Cc1cc(Cl)ncc1C1=C(O)c2ncccc2CS1(=O)=O>>Cc1cc(Cl)ncc1C1=C(OC(=O)C(C)(C)C)c2ncccc2CS1(=O)=O -US08877778B2,2,CCCCC(=O)O.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1>>CCCCC(=O)N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1 -US08975254B2,7,CC(=O)c1ccncc1>>CC(O)c1ccncc1 -US20100041892A1,2,CNOC.COCOc1cc(C(=O)O)n(Cc2ccc(C(F)(F)F)cc2Cl)n1>>COCOc1cc(C(=O)N(C)OC)n(Cc2ccc(C(F)(F)F)cc2Cl)n1 -US06320081B1,1,C=CC[O-].O=[N+]([O-])c1c(F)c(F)c(OCc2ccccc2)c(F)c1F>>C=CCOc1c(F)c(OCc2ccccc2)c(F)c(F)c1[N+](=O)[O-] -US03943176,8,CC1(C)CC(=O)C(SCc2ccc(F)cc2)=C(O)C1.OO>>CC1(C)CC(=O)C(S(=O)Cc2ccc(F)cc2)=C(O)C1 -US06613782B2,3,CCOC(=O)C(Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N=C(c1ccccc1)c1ccccc1.Fc1ccc(I)cc1>>CCOC(=O)C(Cc1ccc(-c2ccc(F)cc2)cc1)N=C(c1ccccc1)c1ccccc1 -US20120316193A1,3,Cc1ccc(Br)s1.OB(O)c1ccc(Cl)cc1>>Cc1ccc(-c2ccc(Cl)cc2)s1 -US20150152127A1,1,COc1ccc(CO[C@@H]2[C@H]3N=C(N(C)C(=O)OC(C)(C)C)S[C@H]3O[C@H](C(C)=O)[C@H]2OCc2ccc(OC)cc2)cc1.NC1CCCC1>>COc1ccc(CO[C@@H]2[C@H]3N=C(N(C)C(=O)OC(C)(C)C)S[C@H]3O[C@H]([C@H](C)NC3CCCC3)[C@H]2OCc2ccc(OC)cc2)cc1 -US20140011798A1,1,CCOC(=O)c1nc(Br)n(C(C)C)c1C(O)c1ccc(Cl)cc1.Nc1cncc(Cl)c1>>CCOC(=O)c1nc(Br)n(C(C)C)c1C(Nc1cncc(Cl)c1)c1ccc(Cl)cc1 -US20120214803A1,8,O=[N+]([O-])c1c(C(O)c2ccc(OC(F)(F)F)cc2)ccc2cccnc12>>O=C(c1ccc(OC(F)(F)F)cc1)c1ccc2cccnc2c1[N+](=O)[O-] -US20090023709A1,1,CC1CCCN1.O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl>>CC1CCCN1c1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccccc1 -US20030069297A1,3,Cc1cc(C)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2ccc(F)cc2)N1>>Cc1cc(C)c(C=C2C(=O)Nc3cccc(-c4ccc(F)cc4)c32)[nH]1 -US20120040984A1,6,CCOC(=O)c1ccc(C2CCC3(CC2)CC3C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)C1CC12CCC(c1ccc(C(=O)O)cc1)CC2 -US07319110B2,6,COC(=O)c1nc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2Cl)n1>>O=C(O)c1nc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2Cl)n1 -US20140303121A1,3,CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Cc1noc(C)c1-c1cnc2c(I)c[nH]c2c1>>CCn1cc(-c2c[nH]c3cc(-c4c(C)noc4C)cnc23)cn1 -US08450336B2,2,CS(=O)(=O)Cl.N[C@H](COC(F)F)C(=O)NCc1ccccc1>>CS(=O)(=O)N[C@H](COC(F)F)C(=O)NCc1ccccc1 -US20150018377A1,6,Cc1cccc(C)c1Oc1ccc(NC(=O)[C@@H](C)NC(=O)OC(C)(C)C)cn1>>Cc1cccc(C)c1Oc1ccc(NC(=O)[C@@H](C)N)cn1 -US20080242694A1,6,CC(C)(C)OC(=O)NCCn1c(CCCCc2ccccc2)nnc1-c1ccc2cnccc2c1>>NCCn1c(CCCCc2ccccc2)nnc1-c1ccc2cnccc2c1 -US20100041760A1,3,C=C(C)B1OC(C)(C)C(C)(C)O1.CN([C@@H]1CCCc2c(OCC(=O)OC(C)(C)C)cccc21)S(=O)(=O)c1cc(Br)cc(C(F)(F)F)c1>>C=C(C)c1cc(C(F)(F)F)cc(S(=O)(=O)N(C)[C@@H]2CCCc3c(OCC(=O)OC(C)(C)C)cccc32)c1 -US06054441,6,Nc1nc2c(ncn2[C@]2(C(=O)[C@H](CCCCNC(=O)OCc3ccccc3)NC(=O)OCC3c4ccccc4-c4ccccc43)O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1>>NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)[C@@]1(n2cnc3c(=O)[nH]c(N)nc32)O[C@H](CO)[C@@H](O)[C@H]1O -US20090099161A1,3,C=CC(=O)N(C)C.COCCc1nc2cnc3ccc(Br)cc3c2n1CCCN1CCCC1=O>>COCCc1nc2cnc3ccc(C=CC(=O)N(C)C)cc3c2n1CCCN1CCCC1=O -US20090131423A1,7,O=c1c2cc(Cl)ncc2ccc2ncc(Cl)cc12>>OC1c2cc(Cl)ncc2C=Cc2ncc(Cl)cc21 -US07999107B2,2,CC1(C)C[C@@H](N)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1.Cc1cc(C(=O)O)n[nH]1>>Cc1cc(C(=O)N[C@@H]2CC(C)(C)Oc3nc(-c4ccc(Cl)cc4Cl)c(-c4ccc(Cl)cc4)cc32)n[nH]1 -US04416828,1,NC(CS)C(=O)O.O=C(O)CCl>>NC(CSCC(=O)O)C(=O)O -US20090069368A1,1,C[O-].ClCc1ncccc1OCc1ccccc1>>COCc1ncccc1OCc1ccccc1 -US04351843,6,COC(=S)c1cc(-c2ccccc2)n(C)c1>>Cn1cc(C(O)=S)cc1-c1ccccc1 -US08071592B2,1,COc1cnc2ccc(=O)n(CC=O)c2c1.O=C(NC[C@@H]1CNC[C@@H]1O)OCc1ccccc1>>COc1cnc2ccc(=O)n(CCN3C[C@H](O)[C@H](CNC(=O)OCc4ccccc4)C3)c2c1 -US05399703,4,CCCCCCOc1ccc(C(=O)Nc2ccccc2Oc2cccc(OCC#N)c2)cc1.[N-]=[N+]=[N-]>>CCCCCCOc1ccc(C(=O)Nc2ccccc2Oc2cccc(OCc3nnn[nH]3)c2)cc1 -US05302621,2,C[C@]12CCC(=O)NC1=CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)O)CC[C@@H]12.NC(Cc1cccs1)c1cccs1>>C[C@]12CCC(=O)NC1=CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)NC(Cc3cccs3)c3cccs3)CC[C@@H]12 -US20150152047A1,1,CCI.Nc1cc(F)ccc1S>>CCSc1ccc(F)cc1N -US20100286390A1,1,CCOC(=O)CBr.C[C@H]1[C@H](Nc2cn[nH]c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C>>CCOC(=O)Cn1ncc(N[C@@H]2C[C@@H]3C[C@H]([C@H]2C)C3(C)C)c(Br)c1=O -US20150141427A1,1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(-c2cnc(Cl)nc2)c1.OCCO>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(-c2cnc(OCCO)nc2)c1 -US20140162971A1,2,Cn1cc(-c2cc(N)ccc2OC2CCOC2)c2cc[nH]c2c1=O.O=S(=O)(Cl)CCF>>Cn1cc(-c2cc(NS(=O)(=O)CCF)ccc2OC2CCOC2)c2cc[nH]c2c1=O -US20090186886A1,1,CN(C)CCN.[O-][n+]1nc(Cl)nc2ccc3c(c21)CCCO3>>CN(C)CCNc1nc2ccc3c(c2[n+]([O-])n1)CCCO3 -US20100197591A1,7,CC(C)(C)Sc1ccc([N+](=O)[O-])cc1>>CC(C)(C)Sc1ccc(N)cc1 -US08354444B2,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.COC(=O)c1ccc(CN)cc1OC>>COC(=O)c1ccc(CNC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1OC -US20140350244A1,1,Clc1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nn1.O=C1COC2(CCNCC2)CN1>>O=C1COC2(CCN(c3ccc(Nc4ncc5c6ccncc6n(C6CCCC6)c5n4)nn3)CC2)CN1 -US08455658B2,9,Cc1nc(NC(=O)c2c(F)cccc2F)sc1-c1ccnc(Br)c1.[C-]#N>>Cc1nc(NC(=O)c2c(F)cccc2F)sc1-c1ccnc(C#N)c1 -US05180834,7,CN(C)CC1CCc2onc(-c3ccccc3)c2C1=O>>CN(C)C[C@@H]1CCc2onc(-c3ccccc3)c2[C@H]1O -US20140235628A1,3,CN(C)C=O.Fc1ccc(I)c(Cl)c1>>O=Cc1c(F)ccc(I)c1Cl -US09040693B2,6,COc1ccccc1C(=O)C(C)(C)c1ccc(F)c(NC(=O)OC(C)(C)C)c1>>COc1ccccc1C(=O)C(C)(C)c1ccc(F)c(N)c1 -US20100152160A1,6,CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(Oc3ccc(F)cc3)CC2)Oc2cc(OCc3ccccc3)c(Cl)cc21>>CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(Oc3ccc(F)cc3)CC2)Oc2cc(O)c(Cl)cc21 -US04963564,3,Brc1ccc2ccccc2n1.C#CCCO>>OCCC#Cc1ccc2ccccc2n1 -US20140194418A1,7,COc1cc(C(=O)NCCN(C)C)ccc1[N+](=O)[O-]>>COc1cc(C(=O)NCCN(C)C)ccc1N -US20130317023A1,2,Cc1cc(S(=O)(=O)Cl)c(C(F)(F)F)o1.Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F>>Cc1cc(S(=O)(=O)Nc2ccc(F)c(Nc3ncccc3-c3ncnc4c3ncn4C3CCCCO3)c2F)c(C(F)(F)F)o1 -US20110112135A1,1,CCc1nc2c(C(F)(F)F)cccn2c1-c1cccc(O)c1.N#CCCCS(=O)(=O)c1cccc(Br)c1>>CCc1nc2c(C(F)(F)F)cccn2c1-c1cccc(Oc2cccc(S(=O)(=O)CCCC#N)c2)c1 -US20110183973A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCOC(C(=O)O)C1>>CC(C)(C)OC(=O)N1CCOC(C(=O)OCc2ccccc2)C1 -US20140369959A1,1,O=C(O)c1cccc(Cl)c1.[N-]=[N+]=N[C@]1(CI)O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1F>>[N-]=[N+]=N[C@]1(COC(=O)c2cccc(Cl)c2)O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1F -US04137232,1,CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CNCC1.O=C(CCl)Nc1ccccc1>>CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CN(CC(=O)Nc2ccccc2)CC1 -US07465808B2,1,CI.COC(=O)Cc1c[nH]c2ccccc12>>COC(=O)Cc1cn(C)c2ccccc12 -US20100093788A1,3,Nc1ccc(Br)cc1[N+](=O)[O-].OB(O)c1ccccc1C(F)(F)F>>Nc1ccc(-c2ccccc2C(F)(F)F)cc1[N+](=O)[O-] -US20080300420A1,3,CCN(CC)C(=O)CC#N.O=Cc1cc(O)c(O)c([N+](=O)[O-])c1>>CCN(CC)C(=O)/C(C#N)=C/c1cc(O)c(O)c([N+](=O)[O-])c1 -US04448784,2,CCOC(=O)Cl.CNCc1cccc(N2CCc3ccccc32)c1>>CCOC(=O)N(C)Cc1cccc(N2CCc3ccccc32)c1 -US20050014941A1,2,CC1CCC(CSc2ccc(F)cc2)C(C(=O)O)C1.N#CCN>>CC1CCC(CSc2ccc(F)cc2)C(C(=O)NCC#N)C1 -US20140227717A1,6,CCOC(=O)CCc1ccc(-n2cnn([C@@H](CC)[C@H](C)O)c2=O)cc1>>CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(CCC(=O)O)cc2)c1=O -US20090227560A1,2,CC(=O)Cl.COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCN(C(=O)OCc3ccccc3)C[C@H]2CCNc2ccccc2)c1-c1ccccc1>>COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCN(C(=O)OCc3ccccc3)C[C@H]2CCN(C(C)=O)c2ccccc2)c1-c1ccccc1 -US20030176454A1,1,Cc1ncccc1Oc1ccc(N)cn1.Clc1nccc2c(-n3cccc3)cccc12>>Cc1ncccc1Oc1ccc(Nc2nccc3c(-n4cccc4)cccc23)cn1 -US20110245250A1,1,Clc1cc(Cl)c(Br)c(Cl)c1.Nc1cccc(CC(=O)NCCO)c1>>O=C(Cc1cccc(Nc2c(Cl)cc(Cl)cc2Cl)c1)NCCO -US20090281097A1,3,CCN(CC)C(=O)c1cccc(Br)c1.OB(O)c1ccncc1>>CCN(CC)C(=O)c1cccc(-c2ccncc2)c1 -US07863332B2,1,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1.Fc1cccc(CBr)c1>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCc2cccc(F)c2)c1 -US20120295900A1,3,COc1ccc(C(NC2=N[C@](C)(c3cc(Br)ccc3F)C(F)(F)C(C)(C)O2)(c2ccccc2)c2ccc(OC)cc2)cc1.OB(O)c1cc(Cl)cc(Cl)c1>>COc1ccc(C(NC2=N[C@](C)(c3cc(-c4cc(Cl)cc(Cl)c4)ccc3F)C(F)(F)C(C)(C)O2)(c2ccccc2)c2ccc(OC)cc2)cc1 -US20090012139A1,3,C#Cc1ccc(OC(F)F)cc1.FCCCC(F)c1cccc(Br)c1>>FCCCC(F)c1cccc(C#Cc2ccc(OC(F)F)cc2)c1 -US20050032829A1,1,CC(C)(N)CN.Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C>>Cc1nc(Cl)c([N+](=O)[O-])c(NCC(C)(C)N)c1C -US20150252022A1,6,O=C(OCc1ccccc1)N1CCC(Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)C1>>c1cc2c(ccn2CC2CCNC2)cc1-c1cnn(C2CCCCO2)c1 -US20120214994A1,2,COc1ccc(N)cc1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>COc1ccc(NC(=O)c2ccc([N+](=O)[O-])cc2)cc1 -US08778950B2,2,CC(C)[C@H](N)CO.O=C(O)c1nn(-c2cc(Cl)ccn2)c2c1C[C@@H]1C[C@H]21>>CC(C)[C@@H](CO)NC(=O)c1nn(-c2cc(Cl)ccn2)c2c1C[C@@H]1C[C@H]21 -US04587256,7,O=C1NC(=O)C2(CCOc3c([N+](=O)[O-])cc(F)cc32)S1>>Nc1cc(F)cc2c1OCCC21SC(=O)NC1=O -US20110257151A1,6,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccccc1NS(=O)(=O)c1cccc(F)c1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1ccccc1NS(=O)(=O)c1cccc(F)c1 -US20150183801A1,1,O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(I)c1.O[C@@H]1CNC[C@H]1O>>O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2C[C@@H](O)[C@H](O)C2)c(I)c1 -US20100305133A1,6,CCCNc1nc2ccc(O)c(C(=O)NCC(=O)OCC)c2nc1-c1ccccc1>>CCCNc1nc2ccc(O)c(C(=O)NCC(=O)O)c2nc1-c1ccccc1 -US20110118231A1,6,COCOc1c(Br)cccc1/C=C/[N+](=O)[O-]>>O=[N+]([O-])/C=C/c1cccc(Br)c1O -US20090062273A1,2,COc1cc(-c2cncc3c2cnn3C)ccc1N.O=C=Nc1cccc(C(F)(F)F)c1>>COc1cc(-c2cncc3c2cnn3C)ccc1NC(=O)Nc1cccc(C(F)(F)F)c1 -US20150232444A1,2,CC1CCCN(C2CCNCC2)C1.O=S(=O)(Cl)c1ccccc1>>CC1CCCN(C2CCN(S(=O)(=O)c3ccccc3)CC2)C1 -US06573388B1,1,C[SiH](C)OC(Cl)[C@H]([C@H](CCl)NC(=O)OC(C)(C)C)C(C)(C)C>>C[SiH](C)OC(Cl)[C@H]([C@@H]1CN1C(=O)OC(C)(C)C)C(C)(C)C -US08114873B2,1,C1COCCN1.O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1ccnc(Cl)c1>>O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1ccnc(N2CCOCC2)c1 -US05968819,9,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN=[N+]=[N-])CC1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1 -US04456471,2,CO.Cc1cccc(C(=O)Cl)c1[N+](=O)[O-]>>COC(=O)c1cccc(C)c1[N+](=O)[O-] -US04353827,8,CSc1cccc2c1C(=O)N1CCC[C@H]1c1c(C(=O)OC(C)(C)C)ncn1-2.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cccc2c1C(=O)N1CCC[C@H]1c1c(C(=O)OC(C)(C)C)ncn1-2 -US20110112151A1,1,O=C(CBr)C12CC3CC(CC(C3)C1)C2.Oc1cncc(Cl)c1>>O=C(COc1cncc(Cl)c1)C12CC3CC(CC(C3)C1)C2 -US04548935,2,CCOC(=O)C1=C(COCc2nnn(CCN)n2)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl.CS(=O)(=O)Cl>>CCOC(=O)C1=C(COCc2nnn(CCNS(C)(=O)=O)n2)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl -US20100298364A1,2,CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)O)cc1.CN(C)CCCCO>>CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN(C)C)cc1 -US08067459B2,3,CC1CSC2=C(O1)c1cc(Br)ccc1C(=O)C2=O.OB(O)c1ccccc1>>CC1CSC2=C(O1)c1cc(-c3ccccc3)ccc1C(=O)C2=O -US06174889B1,6,c1ccc(Cn2ncc3cc(Nc4ncnc5cnc(-c6ccc(C7OCCO7)o6)cc45)ccc32)cc1>>O=Cc1ccc(-c2cc3c(Nc4ccc5c(cnn5Cc5ccccc5)c4)ncnc3cn2)o1 -US20120202777A1,3,CC(CCc1ccc(Br)cc1)(C(=O)NOC1CCCCO1)S(C)(=O)=O.O=[N+]([O-])c1ccc(B(O)O)cc1>>CC(CCc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)(C(=O)NOC1CCCCO1)S(C)(=O)=O -US20100240642A1,1,BrCC1CC1.CCOC(=O)c1c(Cc2cccc(C(F)(F)F)c2)c2ccccc2n1Cc1cc(O)cc(OS(C)(=O)=O)c1>>CCOC(=O)c1c(Cc2cccc(C(F)(F)F)c2)c2ccccc2n1Cc1cc(OCC2CC2)cc(OS(C)(=O)=O)c1 -US08735387B2,6,CCCOc1nc(Cc2ccc(Cl)cc2)nc2oc(-c3cc(C)c(OCC(=O)NCC(=O)OC(C)(C)C)c(C)c3)nc12>>CCCOc1nc(Cc2ccc(Cl)cc2)nc2oc(-c3cc(C)c(OCC(=O)NCC(=O)O)c(C)c3)nc12 -US06218429B1,1,CCC(=O)NCC[C@@H]1CCc2ccc(O)c(CCO)c21>>CCC(=O)NCC[C@@H]1CCc2ccc3c(c21)CCO3 -US20100069629A1,3,COC(=O)c1ccc(B(O)O)cc1.Clc1nc(N2CCOCC2)nc2c1CCN2c1cccnc1>>COC(=O)c1ccc(-c2nc(N3CCOCC3)nc3c2CCN3c2cccnc2)cc1 -US20050049257A1,1,CCc1ccc(C)nc1N.CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1Br>>CCc1ccc(C)nc1Nc1nc(CC)c(-c2ccc(Cl)cc2Cl)nc1CC -US06242641B1,1,CC1CC(=O)CC(C)(C)C1O.N>>CC1CC(N)CC(C)(C)C1O -US20130029961A1,2,CCOC(=O)C(C)(C(=O)OCC)c1ccc(N)c(Br)n1.CS(=O)(=O)Cl>>CCOC(=O)C(C)(C(=O)OCC)c1ccc(NS(C)(=O)=O)c(Br)n1 -US20140128387A1,1,CC(C)Sc1ccccc1N.CSc1nc(Cl)c2c(C)n[nH]c2n1>>CSc1nc(Nc2ccccc2SC(C)C)c2c(C)n[nH]c2n1 -US05155113,2,CC(=O)Cl.O=c1cc(O)cc[nH]1>>CC(=O)Oc1cc[nH]c(=O)c1 -US05091109,1,CCCCCCC(=O)O.CCCCCCc1nnc(-c2ccc3cc(O)ccc3c2)s1>>CCCCCCC(=O)Oc1ccc2cc(-c3nnc(CCCCCC)s3)ccc2c1 -US04051254,2,CNC(=O)Oc1ccc(N)c(C)c1.O=C(Cl)C(Cl)(Cl)Cl>>CNC(=O)Oc1ccc(NC(=O)C(Cl)(Cl)Cl)c(C)c1 -US06498172B1,2,COC(=O)CCc1cccc(CN)c1.O=S(=O)(Cl)c1ccccc1>>COC(=O)CCc1cccc(CNS(=O)(=O)c2ccccc2)c1 -US06642395B1,6,CS(=O)(=O)OCC(OC1CCCCO1)c1ccc(Cl)cc1>>CS(=O)(=O)OC[C@H](O)c1ccc(Cl)cc1 -US20100120785A1,1,Cc1c(CN2CCN(c3nccnc3-c3ccc(CCl)cc3)CC2)cnn1C.c1cn[nH]c1>>Cc1c(CN2CCN(c3nccnc3-c3ccc(Cn4cccn4)cc3)CC2)cnn1C -US20100121052A1,1,Fc1ccnc(Cl)c1.Oc1cc2nc(Nc3cccc(F)c3)ncc2cc1-c1nccs1>>Fc1cccc(Nc2ncc3cc(-c4nccs4)c(Oc4ccnc(Cl)c4)cc3n2)c1 -US20100016337A1,6,CC(C)(C)OC(=O)CNc1nnc(-c2ccccc2)s1>>O=C(O)CNc1nnc(-c2ccccc2)s1 -US08426420B2,2,C1CN[C@H](c2nnn[nH]2)C1.CCCCOC(=O)N1CCN(C(=O)CNC(=O)c2cc(OCC(=O)O)n(-c3ccccc3)n2)CC1>>CCCCOC(=O)N1CCN(C(=O)CNC(=O)c2cc(OCC(=O)N3CCC[C@H]3c3nnn[nH]3)n(-c3ccccc3)n2)CC1 -US20100041686A1,3,CC(C)(C)OC(=O)N1[C@@H](CC=O)COC1(C)C.C[Mg+]>>C[C@@H](O)C[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C -US04436892,2,O=C(Cl)c1c(Cl)cccc1[N+](=O)[O-].c1ccc(-c2ncc[nH]2)cc1>>O=C(c1c(Cl)cccc1[N+](=O)[O-])n1ccnc1-c1ccccc1 -US20090253718A1,6,O=C1c2ccccc2C(=O)N1C(c1ccc(Cl)cc1)c1ccc(-c2ncnc3c2ncn3C2CCCCO2)cc1>>NC(c1ccc(Cl)cc1)c1ccc(-c2ncnc3c2ncn3C2CCCCO2)cc1 -US04673746,6,COc1ccc2c(-c3ccccc3F)noc2c1I>>Oc1ccc2c(-c3ccccc3F)noc2c1I -US08680108B2,9,CC(N=[N+]=[N-])c1cc(Cl)c2ccncc2c1-c1cccc(F)c1>>CC(N)c1cc(Cl)c2ccncc2c1-c1cccc(F)c1 -US20090291949A1,8,Brc1cccc2cnccc12.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc2c(Br)cccc2c1 -US20130030031A1,7,CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C(C)=O)cccc32)c1>>CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C(C)O)cccc32)c1 -US20150203479A1,7,CC(=O)CCn1cnc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)c1>>CC(O)CCn1cnc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)c1 -US08283495B2,7,CC1CCc2ccccc2C1=NCc1ccccc1>>C[C@H]1CCc2ccccc2[C@H]1NCc1ccccc1 -US20110009673A1,3,CCCCC=O.O=C1CCCC1>>CCCCC=C1CCCC1=O -US20030195354A1,6,COc1cc(CCNC(=O)C(=CO)c2ccc(C)cc2)ccc1OCc1ccccc1>>COc1cc(CCNC(=O)C(=CO)c2ccc(C)cc2)ccc1O -US20040242871A1,1,CC1(C)COC(c2ccc(Cl)nc2)=N1.CCO>>CCOc1ccc(C2=NC(C)(C)CO2)cn1 -US20140371278A1,6,COC(=O)c1cc2snnc2c(F)c1Nc1ccc(I)cc1F>>O=C(O)c1cc2snnc2c(F)c1Nc1ccc(I)cc1F -US20100113421A1,2,CN.O=C(O)c1ccnc(F)c1F>>CNC(=O)c1ccnc(F)c1F -US20080293712A1,6,CCOC1(OCC)CCN(C[C@H](N)COc2cncc(-c3cc4c(cnc5cc(OC)c(OC)cc54)c(N)n3)c2)CC1>>COc1cc2ncc3c(N)nc(-c4cncc(OC[C@@H](N)CN5CCC(=O)CC5)c4)cc3c2cc1OC -US20120309771A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(Cl)cc2)CC1 -US20110086882A1,7,COCc1cc(OC)c(-c2csc3c(NC(=O)C4(O)CC4)c(OC)nn23)c(OC)c1>>COCc1cc(OC)c(-c2csc3c(NCC4(O)CC4)c(OC)nn23)c(OC)c1 -US20140080788A1,1,Cc1c(O)cccc1Cl.O=C(N1CCCc2c(Br)cccc21)C1(CO)CC1>>Cc1c(Cl)cccc1OCC1(C(=O)N2CCCc3c(Br)cccc32)CC1 -US20110065707A1,2,CC(C)c1ccc(NC(=O)C2CCNCC2)cc1.O=C(O)CCC1CC1>>CC(C)c1ccc(NC(=O)C2CCN(C(=O)CCC3CC3)CC2)cc1 -US20080139540A1,6,CC(C)(C)OC(=O)NC1CC2(CCN(C(=O)OCc3ccccc3)CC2)CC1O>>CC(C)(C)OC(=O)NC1CC2(CCNCC2)CC1O -US20090029963A1,1,Cc1nn(-c2cccc(C(F)(F)F)c2)c(C2CC2)c1C(=O)N1CCC(=O)CC1.O[C@H]1CCNC1>>Cc1nn(-c2cccc(C(F)(F)F)c2)c(C2CC2)c1C(=O)N1CCC(N2CC[C@H](O)C2)CC1 -US20100298336A1,7,O=Cc1cccc(O)c1Cl>>OCc1cccc(O)c1Cl -US20120289501A1,1,O=C[C@H]1C[C@@H](NC(=O)OCc2ccccc2)C1.OC1CCNCC1>>O=C(N[C@@H]1C[C@H](CN2CCC(O)CC2)C1)OCc1ccccc1 -US20100056527A1,1,CCOC(=O)c1cc(C)[nH]n1.CS(=O)(=O)OCc1cc(Cl)cc2cc(-c3ccccc3)oc12>>CCOC(=O)c1cc(C)n(Cc2cc(Cl)cc3cc(-c4ccccc4)oc23)n1 -US08921576B2,2,C1CNC1.CCOC(=O)CCCc1ccc2c(c1)C1(CCN(C(=O)NC)C1)CN2C(=O)Nc1cnc(C)cn1>>CNC(=O)N1CCC2(C1)CN(C(=O)Nc1cnc(C)cn1)c1ccc(CCCC(=O)N3CCC3)cc12 -US20120184561A1,2,CN1CCC(N(C)c2ccc(N)cc2C(F)(F)F)CC1.O=C(O)Cc1ccc(-n2cnc3ccccc32)cc1>>CN1CCC(N(C)c2ccc(NC(=O)Cc3ccc(-n4cnc5ccccc54)cc3)cc2C(F)(F)F)CC1 -US20120258982A1,1,Nc1ccccc1.O=C(O)c1ccc(C(F)(F)F)nc1Cl>>O=C(O)c1ccc(C(F)(F)F)nc1Nc1ccccc1 -US20020087002A1,1,CI.OCc1cccc(F)c1O>>COc1c(F)cccc1CO -US04168385,1,COC(=O)C(Br)c1ccc(Oc2ccc(Cl)cc2)cc1.Oc1cccc(-c2ccccc2)c1>>COC(=O)C(Oc1cccc(-c2ccccc2)c1)c1ccc(Oc2ccc(Cl)cc2)cc1 -US04987132,9,NO.O=Cc1ccc(OCCCc2ccccc2)cc1>>ON=Cc1ccc(OCCCc2ccccc2)cc1 -US20110178089A1,7,COC(=O)CNC(=O)c1cc(Cl)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl>>O=C(NCCO)c1cc(Cl)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl -US20090318456A1,1,COc1cc(-c2cnc3nc(N)nc(O)c3n2)ccc1OC(C)C.Cc1ccc(N2CCNCC2)cc1>>COc1cc(-c2cnc3nc(N)nc(N4CCN(c5ccc(C)cc5)CC4)c3n2)ccc1OC(C)C -US20030144326A1,1,O[C@H](CBr)c1csc(C(F)(F)F)n1>>FC(F)(F)c1nc([C@H]2CO2)cs1 -US20110184028A1,6,Cc1c(C(=O)c2ccc(F)cc2)cnc(C(=O)NO)c1OCc1ccccc1>>Cc1c(C(=O)c2ccc(F)cc2)cnc(C(=O)NO)c1O -US03997538,1,Clc1ccc(-c2nc(Cl)c3ccccc3n2)cc1Cl.NCC(O)CO>>OCC(O)CNc1nc(-c2ccc(Cl)c(Cl)c2)nc2ccccc12 -US20130005705A1,10,COC(=O)c1c(C)cccc1Br.O=C1CCC(=O)N1Br>>COC(=O)c1c(Br)cccc1CBr -US06875765B2,6,CN(C)c1ccc(S(=O)(=O)N[C@H](C=O)CC(=O)OC(C)(C)C)c(OCCc2cccc3ncccc23)c1>>CN(C)c1ccc(S(=O)(=O)N[C@H](C=O)CC(=O)O)c(OCCc2cccc3ncccc23)c1 -US20120114765A1,9,N.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>NC(=O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US20140005175A1,2,CC(C)(C(=O)O)c1ccc(S(=O)(=O)/C=C/C#N)cc1.COc1cccc(N)c1>>COc1cccc(NC(=O)C(C)(C)c2ccc(S(=O)(=O)/C=C/C#N)cc2)c1 -US20070112003A1,1,C=O.CCOC(=O)CNc1cc(-c2noc(-c3sccc3Cl)n2)ccc1Cl>>CCOC(=O)CN(C)c1cc(-c2noc(-c3sccc3Cl)n2)ccc1Cl -US06824709B2,1,CCCCCBr.Oc1ccc2c(c1)Cc1cc(Br)ccc1-2>>CCCCCOc1ccc2c(c1)Cc1cc(Br)ccc1-2 -US20070232632A1,1,CC(C)C[C@@H](CO)Nc1nc(Cl)ncc1-c1ccsc1.CCOC(=O)N=S(C)(=O)c1ccc(N)cc1>>CCOC(=O)N=S(C)(=O)c1ccc(Nc2ncc(-c3ccsc3)c(N[C@H](CO)CC(C)C)n2)cc1 -US20070161643A1,9,COC(=O)c1cc(F)ccc1Br.N#C[Cu]>>COC(=O)c1cc(F)ccc1C#N -US08569292B2,3,CC(C)(C)NC(=O)c1csc(Br)n1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2nc(C(=O)NC(C)(C)C)cs2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O -US06924300B2,6,CCOC(=O)CCCCCC/C(=N/OCc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)c1ccccc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(/CCCCCCC(=O)O)c2ccccc2)cc1 -US20120302547A1,3,O=C1NCCc2cc(Br)sc21.OB(O)c1ccc(F)cc1>>O=C1NCCc2cc(-c3ccc(F)cc3)sc21 -US20130190370A1,8,O=S(=O)(NC1CCc2c(CCCO)cccc2C1)c1ccc(F)cc1>>O=CCCc1cccc2c1CCC(NS(=O)(=O)c1ccc(F)cc1)C2 -US08030317B2,3,C#C[Si](C)(C)C.Cc1c(Nc2ccc(I)cc2F)c2c(=O)n(C[C@@H](O)CO)cnc2n(C)c1=O>>C#Cc1ccc(Nc2c(C)c(=O)n(C)c3ncn(C[C@@H](O)CO)c(=O)c23)c(F)c1 -US20090099187A1,6,COc1ccc(S(=O)(=O)Nc2ccc(C(F)(F)F)cc2)c2c1C[C@@H](NC(=O)C(F)(F)F)CO2>>COc1ccc(S(=O)(=O)Nc2ccc(C(F)(F)F)cc2)c2c1C[C@@H](N)CO2 -US07563805B2,6,CCOC(=O)C1(C)CN(C(=O)OCc2ccccc2)CC1OC>>COC1CN(C(=O)OCc2ccccc2)CC1(C)C(=O)O -US07795283B2,6,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](c2ccc(NC(=O)OCc3ccccc3)cc2)CC1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](c2ccc(N)cc2)CC1 -US07598386B2,1,C1CCNCC1.C=CCBr>>C=CCN1CCCCC1 -US20080255078A1,3,CCCCC(=O)c1cccc(OCCOCCO)c1.O=C(c1ccc(O)cc1)c1ccc(O)cc1>>CCCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1cccc(OCCOCCO)c1 -US20050148631A1,2,CC(C)(C)C(=O)Cl.Nc1cccc(Br)n1>>CC(C)(C)C(=O)Nc1cccc(Br)n1 -US20100197644A1,5,C[C@H](N)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccc2c(c1)OCC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C[C@H](NC(=O)C(F)(F)F)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccc2c(c1)OCC2 -US04948804,2,O=C(Cl)c1ccccc1.O=C1CCC(OC2CCCC2)N1>>O=C1CCC(OC2CCCC2)N1C(=O)c1ccccc1 -US07081454B2,9,CC(C)(C)OC(=O)C(C(=O)OC(C)(C)C)c1cc(F)cc(F)c1[N+](=O)[O-].N>>CC(C)(C)OC(=O)C(C(=O)OC(C)(C)C)c1cc(F)cc(N)c1[N+](=O)[O-] -US20140018373A1,3,CCSc1ccccc1-c1nc2cc(Br)cnc2n1C.OB(O)c1ccccc1F>>CCSc1ccccc1-c1nc2cc(-c3ccccc3F)cnc2n1C -US20050043358A1,6,CS(=O)(=O)Nc1cc([C@@H](O)CN[C@H](CO)Cc2ccc(Oc3ccc4ccccc4n3)cc2)ccc1OCc1ccccc1>>CS(=O)(=O)Nc1cc([C@@H](O)CN[C@H](CO)Cc2ccc(Oc3ccc4ccccc4n3)cc2)ccc1O -US06482951B2,2,Nc1ncc(Cl)s1.O=C(O)C(CC1CCCCCC1)N1Cc2ccccc2C1=O>>O=C(Nc1ncc(Cl)s1)C(CC1CCCCCC1)N1Cc2ccccc2C1=O -US08003649B2,2,CNC.COC(=O)COCC1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1>>CN(C)C(=O)COCC1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1 -US08946697B1,3,Cc1ccc2c(n1)oc1c(B3OC(C)(C)C(C)(C)O3)cccc12.Fc1ccc(-c2ccnc(Cl)c2)cc1F>>Cc1ccc2c(n1)oc1c(-c3cc(-c4ccc(F)c(F)c4)ccn3)cccc12 -US06586430B1,1,CCOC(CBr)OCC.CCOC(CO)OCC>>CCOC(COCC(OCC)OCC)OCC -US20150266857A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)CCn2ncc3cc(-c4c[nH]c5cc(F)ccc45)ccc32)CC1>>O=C(CCn1ncc2cc(-c3c[nH]c4cc(F)ccc34)ccc21)N1CCNCC1 -US06413448B1,7,COc1ccc(C(=O)CC2CC=C(CCC=C(C)C)CC2)cc1>>COc1ccc(CCC2CC=C(CCC=C(C)C)CC2)cc1 -US20070203210A1,2,CCOC(=O)c1sc(-n2cnc3cc(OC)c(OC)cc32)nc1-c1ccccc1.NC1CC1>>COc1cc2ncn(-c3nc(-c4ccccc4)c(C(=O)NC4CC4)s3)c2cc1OC -US05502072,1,CI.COc1ccc2c(c1)CC(=O)N2>>COc1ccc2c(c1)CC(=O)N2C -US06734203B2,2,CC(=O)OC(C)=O.COCCNC1=CC(=O)c2sc(C(=O)OC)cc2C1=O>>COCCN(C(C)=O)C1=CC(=O)c2sc(C(=O)OC)cc2C1=O -US20050148627A1,6,CCOC(=O)C1=Cc2cc(Cl)cc(C)c2NC1C(F)(F)F>>Cc1cc(Cl)cc2c1NC(C(F)(F)F)C(C(=O)O)=C2 -US20120101078A1,2,CN1CCN([C@@H]2CC[C@H](C(=O)O)CC2)C1=O.Nc1ccc(-c2cc(F)cc(F)c2)cn1>>CN1CCN([C@@H]2CC[C@H](C(=O)Nc3ccc(-c4cc(F)cc(F)c4)cn3)CC2)C1=O -US20110071180A1,2,CC(C)(C)OC(=O)N1CC2CNCC2C1.O=C(O)[C@@H]1C[C@@H]1F>>CC(C)(C)OC(=O)N1CC2CN(C(=O)C3CC3F)CC2C1 -US03966966,6,COc1cc2c(c(Cl)c1Cl)C(=O)C(C)(c1ccccc1)C2=O>>CC1(c2ccccc2)C(=O)c2cc(O)c(Cl)c(Cl)c2C1=O -US20150166564A1,6,Cc1c(C(=O)NN(C)C(=O)OC(C)(C)C)nn(-c2ccccc2)c1N>>CNNC(=O)c1nn(-c2ccccc2)c(N)c1C -US20090186941A1,6,COC(=O)C(C)(CCC(F)(F)C(F)(F)C(F)(F)F)S(=O)(=O)CCC(F)(F)C(F)(F)F>>CC(CCC(F)(F)C(F)(F)C(F)(F)F)(C(=O)O)S(=O)(=O)CCC(F)(F)C(F)(F)F -US20150175562A1,4,BrCCOCCBr.Nc1ccc(Br)c2ccccc12>>Brc1ccc(N2CCOCC2)c2ccccc12 -US20120122840A1,1,COc1cc(N2CCOCC2)ccc1N.O=C(c1nc(Cl)nc2[nH]cnc12)N1CCOCC1>>COc1cc(N2CCOCC2)ccc1Nc1nc(C(=O)N2CCOCC2)c2nc[nH]c2n1 -US20050203151A1,6,CCOC(=O)C(C)(C)Oc1ccc2c(c1)N(CCc1sc(-c3ccc(C(F)(F)F)cc3)nc1C)CC2>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCN1CCc2ccc(OC(C)(C)C(=O)O)cc21 -US20120178736A1,1,CC(C)(C)N1CCNCC1=O.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(C)(C)C)C(=O)C3)n(C)c2n1 -US20150175599A1,6,COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cc3)c3ccc(OC(C)=O)cc23)ccn1>>COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cc3)c3ccc(O)cc23)ccn1 -US20060074102A1,3,Brc1cncc2sc(-c3nnn[nH]3)cc12.OB(O)c1cccc2c1-c1ccccc1-2>>c1ccc2c(c1)-c1cccc(-c3cncc4sc(-c5nnn[nH]5)cc34)c1-2 -US20070190071A1,6,CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CC(C)(C)O)S(=O)(=O)c3cccc(CC(=O)OC)c3)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CC(C)(C)O)S(=O)(=O)c3cccc(CC(=O)O)c3)c2n1 -US20130196998A1,6,Cc1ccccc1Sc1ccc2c(c1)OCC21CCN(CCC(=O)OC(C)(C)C)CC1>>Cc1ccccc1Sc1ccc2c(c1)OCC21CCN(CCC(=O)O)CC1 -US05663162,4,CC(C)(C)OC(=O)NCC(N)=S.CCOC(=O)C(=O)CBr>>CCOC(=O)c1csc(CNC(=O)OC(C)(C)C)n1 -US04490382,1,CC(C)(C)C(=O)OCOC(=O)C1N2C(=O)C(N)[C@H]2SC1(C)C.Fc1nc2ccccc2[nH]1>>CC(C)(C)C(=O)OCOC(=O)C1N2C(=O)C(Nc3nc4ccccc4[nH]3)[C@H]2SC1(C)C -US08691991B2,1,CCOC(=O)c1ncc(Cc2ccc(F)cc2)cc1N.O=CCN1CCCS1(=O)=O>>CCOC(=O)c1ncc(Cc2ccc(F)cc2)cc1NCCN1CCCS1(=O)=O -US20080161365A1,7,CCOC(=O)c1cc(C(=O)C=Cc2ccc(C(=O)OC(C)(C)C)cc2)cc(C)n1>>CCOC(=O)c1cc(C(=O)CCc2ccc(C(=O)OC(C)(C)C)cc2)cc(C)n1 -US20110124642A1,2,Nn1nc(C(F)(F)F)c2ccccc2c1=O.O=C(O)Cc1ccc(C(F)(F)F)cc1>>O=C(Cc1ccc(C(F)(F)F)cc1)Nn1nc(C(F)(F)F)c2ccccc2c1=O -US08178522B2,2,COC(=O)c1sc(/C=C/c2c(-c3ccccc3)noc2C)nc1C.NCCO>>Cc1nc(/C=C/c2c(-c3ccccc3)noc2C)sc1C(=O)NCCO -US03993772,1,Cc1cc(C(=O)Cl)c(C)o1.ONC1CCCCC1>>Cc1cc(C(=O)N(O)C2CCCCC2)c(C)o1 -US20130090323A1,3,CC1(C)OB(c2ccc(F)c(C(F)F)c2)OC1(C)C.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1I>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1ccc(F)c(C(F)F)c1 -US20070265270A1,1,C1CCNC1.COc1cc2nncc(-n3ncc4c(Br)cccc43)c2cc1OC>>COc1cc2nncc(-n3ncc4c(N5CCCC5)cccc43)c2cc1OC -US07271262B2,6,CC(C)(C)OC(=O)Nc1cccc(Sc2cn(C3CCCC3)c3ncnc(N)c23)c1>>Nc1cccc(Sc2cn(C3CCCC3)c3ncnc(N)c23)c1 -US07923573B2,3,C#C[Si](C)(C)C.COC(=O)Cc1ccc(Br)cc1I>>COC(=O)Cc1ccc(Br)cc1C#C[Si](C)(C)C -US20090233900A1,3,CB1OB(C)OB(C)O1.CC(C)(C)OC(=O)N[C@H]1CCCC[C@@H]1Nc1cc(Cl)c(Br)cc1C#N>>Cc1cc(C#N)c(N[C@H]2CCCC[C@@H]2NC(=O)OC(C)(C)C)cc1Cl -US20090093459A1,2,CC(C)(C)C(=O)ON[C@@H](CSc1cccc(Oc2ccccc2)c1N)C(=O)O>>CC(C)(C)C(=O)ON[C@H]1CSc2cccc(Oc3ccccc3)c2NC1=O -US20130331376A1,1,CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C1CCCC1.Fc1ccc(-c2ncc[nH]2)nc1>>CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cn3)nc2N1C1CCCC1 -US08153805B2,2,C1CCN(C2CCNCC2)C1.Cc1c(Br)cccc1C(=O)O>>Cc1c(Br)cccc1C(=O)N1CCC(N2CCCC2)CC1 -US06297223B1,3,C#C[Si](C)(C)C.O=c1[nH]cc(I)c(=O)[nH]1>>C[Si](C)(C)C#Cc1c[nH]c(=O)[nH]c1=O -US20040235891A1,2,CC(C(=O)O)c1ccc(F)cc1.COc1ccc(CCN)cc1>>COc1ccc(CCNC(=O)C(C)c2ccc(F)cc2)cc1 -US20130281415A9,8,COc1cc(NC(=O)CCN(C)[C@@H]2CC[C@@H](OC(=O)C(O)(c3cccs3)c3cccs3)CC2)c(Cl)cc1CO>>COc1cc(NC(=O)CCN(C)[C@@H]2CC[C@@H](OC(=O)C(O)(c3cccs3)c3cccs3)CC2)c(Cl)cc1C=O -US05728699,1,FC(F)Cl.O=C(c1ccc(Cl)cc1)c1ccc(CS)cc1>>O=C(c1ccc(Cl)cc1)c1ccc(CSC(F)F)cc1 -US20080146612A1,3,CC(C)(C)OC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1Cl.COC(=O)c1nc(Cl)ccc1Cl>>COC(=O)c1nc(-c2ccc(Cl)c(C(=O)OC(C)(C)C)c2)ccc1Cl -US08026257B2,1,CC(=O)[O-].C[Si](C)(C)CCOCn1ncc2cc(Br)cc(CBr)c21>>CC(=O)OCc1cc(Br)cc2cnn(COCC[Si](C)(C)C)c12 -US20080242683A1,6,O=C(OCc1ccccc1)N1CCN(C2CCN(c3nc(NCC(c4ccccc4)c4ccccc4)c4ncn([C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)c4n3)C2)CC1>>OC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CCC(N5CCNCC5)C4)nc32)[C@H](O)[C@@H]1O -US20110070297A1,1,CC(C)CN.O=[N+]([O-])c1ccc(Br)cc1F>>CC(C)CNc1cc(Br)ccc1[N+](=O)[O-] -US20110269781A1,1,BrCCC1CCOC1.CCCCNc1nc(N)c2nc(OC)[nH]c2n1>>CCCCNc1nc(N)c2nc(OC)n(CCC3CCOC3)c2n1 -US20060100226A1,2,COc1cccc(-c2nc(SCc3cccc(N)c3)[nH]c(=O)c2C#N)c1.O=C=Nc1ccc(Cl)c(Cl)c1>>COc1cccc(-c2nc(SCc3cccc(NC(=O)Nc4ccc(Cl)c(Cl)c4)c3)[nH]c(=O)c2C#N)c1 -US20130196982A1,3,CC1(C)OB(c2ccc(NC(=O)NCCO)cc2)OC1(C)C.C[C@H]1COCCN1c1nc(Cl)cc(-c2cc(F)ccc2S(C)(=O)=O)n1>>C[C@H]1COCCN1c1nc(-c2ccc(NC(=O)NCCO)cc2)cc(-c2cc(F)ccc2S(C)(=O)=O)n1 -US04939140,2,CC(O)c1nc2cc(C(F)(F)F)ccc2s1.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)c1nc2cc(C(F)(F)F)ccc2s1 -US20100216788A1,2,CC(C)(O)CC(=O)O.Cc1cc(Nc2ncnc3ccn(CCN)c23)ccc1Oc1cccc(OCC(C)C)c1>>Cc1cc(Nc2ncnc3ccn(CCNC(=O)CC(C)(C)O)c23)ccc1Oc1cccc(OCC(C)C)c1 -US20060205759A1,9,CCOC(=O)C1CCc2sc3ccc(Br)cc3c2C1.N#C[Cu]>>CCOC(=O)C1CCc2sc3ccc(C#N)cc3c2C1 -US20090291942A1,1,CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CO)cc1.OC1CCNCC1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CN2CCC(O)CC2)cc1 -US20090036495A1,1,CC(C)CO.COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2O)cc1>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2OCC(C)C)cc1 -US20110294850A1,2,CC1(C)CN(Cc2cccnc2)c2ccc(O)cc21.O=C=NCc1ccccc1>>CC1(C)CN(Cc2cccnc2)c2ccc(OC(=O)NCc3ccccc3)cc21 -US07750161B2,6,CCN(C1CCN(C(=O)OC(C)(C)C)CC1)S(=O)(=O)c1ccc(OC)cc1>>CCN(C1CCNCC1)S(=O)(=O)c1ccc(OC)cc1 -US20110212945A1,1,Cc1cc(N)cnc1Br.O=C(O)c1cc(Cl)ccc1Cl>>Cc1cc(Nc2ccc(Cl)cc2C(=O)O)cnc1Br -US06358515B2,1,CC(C)(C)c1cc(O)ccc1OCc1ccccc1.ClCC1CO1>>CC(C)(C)c1cc(OCC2CO2)ccc1OCc1ccccc1 -US20090093454A1,1,CN1CCNCC1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>CN1CCN(c2cccc3nc(CN4CCC[C@H]5CCc6cccnc6[C@H]54)cn23)CC1 -US05245051,1,COc1ccc2c(c1)OC(CN)CO2.O=c1ccoc2cc(OCCCBr)ccc12>>COc1ccc2c(c1)OC(CNCCCOc1ccc3c(=O)ccoc3c1)CO2 -US20020045747A1,1,CCC(=O)C(=O)OCC(C)C.Nc1ccc(Cl)c(Cl)c1>>CCC(Nc1ccc(Cl)c(Cl)c1)C(=O)OCC(C)C -US20110021523A1,7,COc1cc([N+](=O)[O-])ccc1Cl>>COc1cc(N)ccc1Cl -US06251912B1,2,CC(C)C(C)(N)C#CC(=O)O.Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1>>CC(C)C(C)(N)C#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 -US07067518B2,2,COc1ccccc1N1CCN(C[C@H](N)Cc2ccccn2)CC1.O=C(Cl)C1CCCCC1>>COc1ccccc1N1CCN(C[C@@H](Cc2ccccn2)NC(=O)C2CCCCC2)CC1 -US07592456B2,8,COC(=O)c1ccccc1S(=O)(=O)c1ccc2nc(-c3ccc(F)cc3)ccc2c1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1ccccc1S(=O)(=O)c1ccc2c(ccc(-c3ccc(F)cc3)[n+]2[O-])c1 -US04806549,1,CCCC(=O)c1cnc2c(C)cccc2c1Cl.COc1ccccc1N>>CCCC(=O)c1cnc2c(C)cccc2c1Nc1ccccc1OC -US20150259295A1,3,COC(=O)c1c(Br)cnn1C.OB(O)c1ccc(F)cc1>>COC(=O)c1c(-c2ccc(F)cc2)cnn1C -US20140058098A1,6,CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(O[C@@H](C)C(=O)OC(C)(C)C)cc1OCC2>>CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(O[C@@H](C)C(=O)O)cc1OCC2 -US07576222B2,2,CC#CCOc1ccc(S(=O)(=O)Cl)cc1.Cc1ccc2[nH]cc(CC(N)C(=O)O)c2c1>>CC#CCOc1ccc(S(=O)(=O)NC(Cc2c[nH]c3ccc(C)cc23)C(=O)O)cc1 -US20090163552A1,2,COC(=O)c1cc(F)c(N)c(F)c1.O=C(O)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21>>COC(=O)c1cc(F)c(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(F)c1 -US07504522B2,9,CC(C)(C)NC(=O)N1CC(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2Cl)C1>>CC(C)(C)NC(=O)N1CC(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1 -US20100048636A1,7,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)c2cccc(F)c2F)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](C(O)c2cccc(F)c2F)C1 -US04282361,2,CCO.Cc1n[nH]c(C(=O)O)c1[N+](=O)[O-]>>CCOC(=O)c1[nH]nc(C)c1[N+](=O)[O-] -US20050027121A1,1,CC[C@@H]1COCCN1.ClCC#CCCl>>CC[C@@H]1COCCN1CC#CCCl -US20090036492A1,1,CCCOc1cc(OC)c(C(N)=O)c2c1[C@]1(C)C(=O)C(C(C)=O)=C(O)C=C1O2.Cc1ccc2ccccc2c1C=O>>CCCOc1cc(OC)c(C(=O)NCc2c(C)ccc3ccccc23)c2c1[C@]1(C)C(=O)C(C(C)=O)=C(O)C=C1O2 -US20070191353A1,1,COc1ccc(O)cc1OC.N#CCBr>>COc1ccc(OCC#N)cc1OC -US20050148643A1,2,Cc1c(C)c(C)c2[nH]c(C(O)CO[Si](C)(C)C(C)(C)C)nc2c1C.O=C=Nc1ccc(Cl)c(Cl)c1>>Cc1c(C)c(C)c2[nH]c(C(CO[Si](C)(C)C(C)(C)C)OC(=O)Nc3ccc(Cl)c(Cl)c3)nc2c1C -US03993643,1,ClCc1ccccn1.O=[N+]([O-])c1ccc(C=Cc2ncc[nH]2)o1>>O=[N+]([O-])c1ccc(C=Cc2nccn2Cc2ccccn2)o1 -US20080176832A1,1,Brc1ccc(-n2cc3c(n2)CCN(C2CCC2)CC3)cc1.CN1CC(=O)NC1=O>>CN1CC(=O)N(c2ccc(-n3cc4c(n3)CCN(C3CCC3)CC4)cc2)C1=O -US20110135600A1,3,Brc1cnc2nnn(Cc3cccc(-c4ncc(OCCN5CCOCC5)cn4)c3)c2n1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2cnc3nnn(Cc4cccc(-c5ncc(OCCN6CCOCC6)cn5)c4)c3n2)cn1 -US07678787B2,9,NO.O=Cc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1>>O=C(NCc1cccnc1)c1ccc2n1Cc1ccccc1N(C(=O)c1ccc(-c3ccccc3/C=N/O)cc1)C2 -US04404224,1,CC(C)NCC(Cl)c1ccc(O)c(NS(C)(=O)=O)c1.CCO>>CCOC(CNC(C)C)c1ccc(O)c(NS(C)(=O)=O)c1 -US04939279,6,CCCCCCCCCCCOc1ccc(OC)cc1C=O>>CCCCCCCCCCCOc1ccc(O)cc1C=O -US07300944B2,7,O=C1CC(c2[nH]nc3c2C(c2ccccc2)CC(=O)N3)C1>>O=C1CC(c2ccccc2)c2c(n[nH]c2C2CC(O)C2)N1 -US08153805B2,3,Cc1cc(Br)cc(C)c1C(=O)N1CCC(N2CCCC2)CC1.OB(O)c1cccc(C(F)(F)F)c1>>Cc1cc(-c2cccc(C(F)(F)F)c2)cc(C)c1C(=O)N1CCC(N2CCCC2)CC1 -US05541229,6,CCCCc1nc2ccc(O)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2ccc(O)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20090054681A1,3,CC(=O)Oc1c(C)cccc1C(Br)CCBr>>CC(=O)Oc1c(C)cccc1C1CC1 -US06960578B2,7,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2)cc1N -US20070032470A1,2,CC(=O)c1cc(C(=O)O)cc(N2CCCCS2(=O)=O)c1.COc1cccc(CN(C[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)C(=O)OC(C)(C)C)c1>>COc1cccc(CN(C[C@@H](O)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cc(C(C)=O)cc(N3CCCCS3(=O)=O)c2)C(=O)OC(C)(C)C)c1 -US08916599B2,6,CCOC(=O)c1ccc2c(c1)nc(Nc1c(F)cccc1F)n2C>>Cn1c(Nc2c(F)cccc2F)nc2cc(C(=O)O)ccc21 -US08222246B2,2,COC(=O)c1ccc(OCc2c(-c3ccc(F)c(F)c3)noc2CO)nc1.NC1CCOCC1>>O=C(NC1CCOCC1)c1ccc(OCc2c(-c3ccc(F)c(F)c3)noc2CO)nc1 -US04293557,2,CC(Br)C(=O)O.CC(c1cccc(OCCCN)c1)N1CCCC1>>CC(Br)C(=O)NCCCOc1cccc(C(C)N2CCCC2)c1 -US20130090333A1,3,CC1(C)OB(c2ccc3c(c2)OCC(c2c(F)cccc2F)N3)OC1(C)C.Cc1cc(-c2nnn(C)n2)ncc1Br>>Cc1cc(-c2nnn(C)n2)ncc1-c1ccc2c(c1)OCC(c1c(F)cccc1F)N2 -US20060160864A1,6,CCCCOCCOc1ccc(-c2ccc(N3CCC(CC(=O)OCC)C3)c(/C=C(\C)C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCC(CC(=O)O)C3)c(/C=C(\C)C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1 -US06699861B1,9,Cc1cc(Br)c(N)cc1Cl.N#C[Cu]>>Cc1cc(C#N)c(N)cc1Cl -US20060036101A1,2,CCN(CC)C(=O)C(=O)c1c[nH]c2ccc(N)cc12.O=S(=O)(Cl)c1cccc2ccccc12>>CCN(CC)C(=O)C(=O)c1c[nH]c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc12 -US20070082912A1,4,CC(=O)CCC(=O)c1cc(Cl)ccc1OCc1cccc(F)c1F.Nc1cc(C(=O)O)ccc1F>>Cc1ccc(-c2cc(Cl)ccc2OCc2cccc(F)c2F)n1-c1cc(C(=O)O)ccc1F -US05612352,3,CN(C)C=O.Fc1ccc(-c2ccc(Br)cc2)cc1>>O=Cc1ccc(-c2ccc(F)cc2)cc1 -US20150203472A1,3,COc1ccc(-n2cnc3ccc(Br)cc32)cc1.OB(O)c1ccnn1-c1ccc(F)cc1>>COc1ccc(-n2cnc3ccc(-c4ccnn4-c4ccc(F)cc4)cc32)cc1 -US20140107109A1,1,C[O-].Clc1cnc2c(Cl)nccc2n1>>COc1cnc2c(Cl)nccc2n1 -US20040058915A1,6,CCOC(=O)CC1CCc2cc(OCCc3cccc(NC(=O)OC(C)(C)C)n3)ccc2C1>>CC(C)(C)OC(=O)Nc1cccc(CCOc2ccc3c(c2)CCC(CC(=O)O)C3)n1 -US08383621B2,6,CCc1cc(OC)c(Oc2ccc(C(=O)N3CCN(CC(N)=O)C(=O)C3)cc2F)cc1F>>CCc1cc(O)c(Oc2ccc(C(=O)N3CCN(CC(N)=O)C(=O)C3)cc2F)cc1F -US20140094462A1,3,C=CCCCC(=O)O[C@@H](CNC(=O)[C@@H](CC=C)CC(=O)OC(C)(C)C)c1ccccc1>>CC(C)(C)OC(=O)C[C@@H]1CC=CCCCC(=O)O[C@H](c2ccccc2)CNC1=O -US20130005705A1,7,O=C1c2c(cccc2N2CCc3ccc([N+](=O)[O-])cc3C2)CN1CCc1ccc2ccccc2n1>>Nc1ccc2c(c1)CN(c1cccc3c1C(=O)N(CCc1ccc4ccccc4n1)C3)CC2 -US20060160832A1,1,BrCCCBr.N#Cc1cc2c(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)ccnc2cc1O>>N#Cc1cc2c(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)ccnc2cc1OCCCBr -US07745438B2,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1[C@@H]([C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)COC1(C)C>>CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C -US06303793B1,3,C#CCNC.COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(F)c(I)c21>>CNCC#Cc1c(F)ccc2c1/C(=C/c1[nH]ccc1OC)C(=O)N2 -US20020193402A1,6,O[C@@H]1CC[C@H]2CC[C@]1(c1ccccc1)N2Cc1ccccc1>>O[C@@H]1CC[C@H]2CC[C@]1(c1ccccc1)N2 -US20110301353A1,3,COCC(=O)Nc1cc2c(cc1F)CC(=O)N2.Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCOCC1)CC2>>COCC(=O)Nc1cc2c(cc1F)C(=Cc1[nH]c3c(c1C)C(=O)N(CCN1CCOCC1)CC3)C(=O)N2 -US20140162985A1,3,CB1OB(C)OB(C)O1.CCC12CCC3(CC1CCCc1cc(N)c(Br)cc12)OCCO3>>CCC12CCC3(CC1CCCc1cc(N)c(C)cc12)OCCO3 -US20120270203A1,6,COC(=O)C[C@H](CSCc1ccc(OC)cc1)NC(=O)OC(C)(C)C>>COC(=O)C[C@@H](N)CSCc1ccc(OC)cc1 -US05672601,1,CC(=O)N1C2CCC1CNC2.ClCC=Cc1ccccc1>>CC(=O)N1C2CCC1CN(CC=Cc1ccccc1)C2 -US08362030B2,3,CCCC[Sn](/C=C\OCC)(CCCC)CCCC.COC(=O)c1cccc2nc(-c3ccc(C#N)cc3)c(Br)n12>>CCO/C=C/c1c(-c2ccc(C#N)cc2)nc2cccc(C(=O)OC)n12 -US05437815,7,CCC(=O)c1ccc(-c2ccc(Br)cc2F)cc1>>CCCc1ccc(-c2ccc(Br)cc2F)cc1 -US20100179109A1,3,COC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1Br.OB(O)c1ccccc1>>COC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1-c1ccccc1 -US20070082912A1,2,Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1.NCc1ccccc1>>Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)NCc2ccccc2)c1 -US08013156B2,1,CC(C)(C)OC(=O)N1CCN(c2ccccc2O)CC1.ClCc1ccncc1>>CC(C)(C)OC(=O)N1CCN(c2ccccc2OCc2ccncc2)CC1 -US06933311B2,2,CC(C(=O)O)c1cccc2cnccc12.NCc1ccc(N2CCCCCC2)c(F)c1>>CC(C(=O)NCc1ccc(N2CCCCCC2)c(F)c1)c1cccc2cnccc12 -US20110178068A1,1,CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)OCI.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1>>CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)OC[N+]1(C)CCN(C2=Nc3ccccc3Nc3sc(C)cc32)CC1 -US20150225373A1,1,Nc1cccc(F)n1.OCCN1CCOCC1>>Nc1cccc(OCCN2CCOCC2)n1 -US09000025B2,7,Cc1c(Sc2cccc(/C=C/C(=O)O)c2)c2ccc(Cl)cc2n1Cc1ccccc1>>Cc1c(Sc2cccc(CCC(=O)O)c2)c2ccc(Cl)cc2n1Cc1ccccc1 -US20010031788A1,6,COC(=O)CC(NS(=O)(=O)c1ccccc1)c1cccc(OCc2cccc(NC(=N)N)c2)c1>>N=C(N)Nc1cccc(COc2cccc(C(CC(=O)O)NS(=O)(=O)c3ccccc3)c2)c1 -US20140296261A1,3,CC1(C)OB(c2cccnc2F)OC1(C)C.Clc1ncnc2c1ncn2C1CCCCO1>>Fc1ncccc1-c1ncnc2c1ncn2C1CCCCO1 -US08673891B2,1,C[C@H](Nc1nc(Cl)cc(Cl)n1)c1ccc(F)cc1.OCC1(O)CCNCC1>>C[C@H](Nc1nc(Cl)cc(N2CCC(O)(CO)CC2)n1)c1ccc(F)cc1 -US20090181963A1,2,COC(Cn1nnc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21)OC.O=C=Nc1ccc(F)cc1>>COC(Cn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(F)cc4)cc3)nc21)OC -US20130040930A1,1,Cc1ccc(N2CCN(C(=O)c3c(F)cc(Br)cc3F)CC2)c(C)c1.O=C1CCCN1>>Cc1ccc(N2CCN(C(=O)c3c(F)cc(N4CCCC4=O)cc3F)CC2)c(C)c1 -US05010077,2,CC(=O)OC(C)=O.CCOC(=O)c1ncc2[nH]c3ccc(N)cc3c2c1C>>CCOC(=O)c1ncc2[nH]c3ccc(NC(C)=O)cc3c2c1C -US20050004187A1,1,CC(C)(C)OC(=O)CBr.CC(C)(C)[Si](C)(C)Oc1ccc2cc[nH]c2c1>>CC(C)(C)OC(=O)Cn1ccc2ccc(O[Si](C)(C)C(C)(C)C)cc21 -US20090149466A1,1,O=Cc1c(Cl)ccc(Cl)c1Cl.O=c1cc(N2CCNCC2)nc[nH]1>>O=c1cc(N2CCN(Cc3c(Cl)ccc(Cl)c3Cl)CC2)nc[nH]1 -US20120142735A1,1,COCCBr.Cc1cc(Cl)cc2cc[nH]c12>>COCCn1ccc2cc(Cl)cc(C)c21 -US08163773B2,7,COCCCOc1cc(OC)cc(C(=O)NC2CC2)c1>>COCCCOc1cc(CNC2CC2)cc(OC)c1 -US09090599B2,2,COc1cc(CN)on1.Cc1cc(-c2cc(C(=O)O)ncc2OCC(F)(F)F)ccc1Cl>>COc1cc(CNC(=O)c2cc(-c3ccc(Cl)c(C)c3)c(OCC(F)(F)F)cn2)on1 -US07368578B2,3,CC(C)c1nc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cs1.CCOC(=O)Cc1ccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4C=O)cc3OC)c(C)o2)cc1>>CCOC(=O)Cc1ccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4/C=C\c4csc(C(C)C)n4)cc3OC)c(C)o2)cc1 -US07547779B2,1,CC(C)(C)OC(=O)Nc1cccc(O)c1.O=[N+]([O-])c1cnc(Cl)cc1Nc1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)Nc1cccc(Oc2cc(Nc3ccc(OCc4ccccc4)cc3)c([N+](=O)[O-])cn2)c1 -US20110183964A1,1,Brc1ccc(C2CNCCN2)cc1.CI>>CN1CCNC(c2ccc(Br)cc2)C1 -US04141899,2,CC(C)N=C=O.c1nc2c([nH]1)CCNC2>>CC(C)NC(=O)N1CCc2[nH]cnc2C1 -US08354411B2,6,C[Si](C)(C)C#Cc1nn(-c2cccc(C(F)(F)F)c2)ccc1=O>>C#Cc1nn(-c2cccc(C(F)(F)F)c2)ccc1=O -US20140350244A1,6,CCOC(=O)CN1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1>>O=C(O)CN1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 -US05726165,1,BrCc1ccccc1.Oc1ccc(CCNC[C@H](O)COc2ccc(OCc3ccccc3)cc2)cc1>>Oc1ccc(CCN(Cc2ccccc2)C[C@H](O)COc2ccc(OCc3ccccc3)cc2)cc1 -US20090312310A1,2,CC(C)C1=C(C(=O)O)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21.CN1CCNCC1>>CC(C)C1=C(C(=O)N2CCN(C)CC2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21 -US05183902,9,N.O=C(Cl)N1CC(Oc2cccc(C(F)(F)F)c2)C1>>NC(=O)N1CC(Oc2cccc(C(F)(F)F)c2)C1 -US20110071127A1,6,CCOC(=O)C(C)(C)S(=O)(=O)c1ccc(Cl)nc1>>CC(C)(C(=O)O)S(=O)(=O)c1ccc(Cl)nc1 -US20070249670A1,7,CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1[N+](=O)[O-])C1CCCCC1>>CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1N)C1CCCCC1 -US20150210688A1,6,COC(=O)c1cc(-c2nc3c([nH]2)CCN(C(=O)OC(C)(C)C)CC3)c(C2CCC2)cc1C>>COC(=O)c1cc(-c2nc3c([nH]2)CCNCC3)c(C2CCC2)cc1C -US20080161344A1,2,COc1cc2c(cc1OC)CNCC2.O=C(O)c1ccnc(Cl)c1>>COc1cc2c(cc1OC)CN(C(=O)c1ccnc(Cl)c1)CC2 -US20100160369A1,9,NC(=O)c1ccc(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)c(Cl)c1>>N#Cc1ccc(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)c(Cl)c1 -US04171373,2,CCO.O=C(O)C=Cc1ccc(C2CCCCC2)c(Cl)c1>>CCOC(=O)C=Cc1ccc(C2CCCCC2)c(Cl)c1 -US20060154974A1,2,Nc1nccs1.O=C(O)c1ccc2c(c1)OCCN2>>O=C(Nc1nccs1)c1ccc2c(c1)OCCN2 -US20150166564A1,2,CCOc1cc(N)n(-c2ccccc2)n1.O=C(Cl)Oc1ccccc1>>CCOc1cc(NC(=O)Oc2ccccc2)n(-c2ccccc2)n1 -US20060030609A1,7,CC(C)(C)N1C(=O)Cc2cc([N+](=O)[O-])ccc21>>CC(C)(C)N1C(=O)Cc2cc(N)ccc21 -US20040167131A1,2,CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(N)c(F)c1.CC(C)(C)OC(=O)NC1(C(=O)O)CC1>>CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(NC(=O)OC(C)(C)C)CC2)c(F)c1 -US08580965B2,2,COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)O)c(C)c1.OC1(c2cccs2)CCNCC1>>COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N2CCC(O)(c3cccs3)CC2)c(C)c1 -US20130231306A1,7,CCOC(=O)C1CC=C(c2ccc(N)c3c(=O)c(C)c[nH]c23)CC1>>CCOC(=O)[C@H]1CC[C@@H](c2ccc(N)c3c(=O)c(C)c[nH]c23)CC1 -US08063234B2,7,Cc1ccc(C(=O)C2CC2C#N)cc1>>Cc1ccc(C(O)C2CC2C#N)cc1 -USH0000642,1,CC(=O)NC[C@@H](NC(=O)OCc1ccccc1)C(=O)O.CCI>>CCOC(=O)[C@@H](CNC(C)=O)NC(=O)OCc1ccccc1 -US20090239864A1,1,Cn1c(N2CCOCC2)nc(-c2ccncc2F)cc1=O.NCCc1ccc(F)cc1>>Cn1c(N2CCOCC2)nc(-c2ccncc2NCCc2ccc(F)cc2)cc1=O -US20140349922A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc2c(c1)Cc1ccccc1-2>>CC(C)(C)OC(=O)Nc1ccc2c(c1)Cc1ccccc1-2 -US09067898B1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(O)c2ccsc12>>CCOC(=O)/C=C/c1ccc(O)c2ccsc12 -US20040204454A1,2,N[C@H]1CCCC[C@H]1N.O=S(=O)(O)c1ccc(I)cc1>>N[C@H]1CCCC[C@H]1NS(=O)(=O)c1ccc(I)cc1 -US20130045986A1,4,CS(=O)(=O)c1ccc(C(=O)O)c(F)c1.Nc1ccc(Br)cc1N>>CS(=O)(=O)c1ccc(-c2nc3cc(Br)ccc3[nH]2)c(F)c1 -US20080293712A1,2,CC(C)(C)OC(=O)N1CCC[C@H](O)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC[C@H](OS(C)(=O)=O)C1 -US06310099B1,7,CC(=O)c1ccc(Nc2c(F)c(F)cc(F)c2F)c(CC(=O)N(C)C)c1>>CCc1ccc(Nc2c(F)c(F)cc(F)c2F)c(CC(=O)N(C)C)c1 -US04377669,2,CCO.O=C(O)CCCCc1ccccc1>>CCOC(=O)CCCCc1ccccc1 -US20140121200A1,1,CNC1CCOCC1.O=[N+]([O-])c1ccc(Br)nc1>>CN(c1ccc([N+](=O)[O-])cn1)C1CCOCC1 -US06806365B2,6,O=C(N[C@@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)C(=O)O)OCC1c2ccccc2-c2ccccc21>>N[C@@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)C(=O)O -US05268380,7,O=C1CCc2cc(C(=O)c3ccccc3)ccc2N1>>O=C1CCc2cc(C(O)c3ccccc3)ccc2N1 -US06376491B1,6,CCCc1c(C(=O)OCC)oc2cccc(OCCCN(C(=O)OC(C)(C)C)C(C)(C)C)c12>>CCCc1c(C(=O)OCC)oc2cccc(OCCCNC(C)(C)C)c12 -US20040157886A1,2,Cc1ccc(CC2CCNCC2)cc1.O=C1Cc2cc(NC(=O)C(=O)O)ccc2N1>>Cc1ccc(CC2CCN(C(=O)C(=O)Nc3ccc4c(c3)CC(=O)N4)CC2)cc1 -US20120252841A1,1,COC(=O)CCS.O=C(NCc1cccs1)c1cc2ccccc2nc1Cl>>COC(=O)CCSc1nc2ccccc2cc1C(=O)NCc1cccs1 -US20100222319A1,2,CN.O=C(O)c1ccc(Cl)nc1Cl>>CNC(=O)c1ccc(Cl)nc1Cl -US20130158009A1,1,Cc1cc(N[C@H]2CCN(C3CCNCC3)C2=O)c(F)cc1S(C)(=O)=O.Clc1cnc(Cl)cn1>>Cc1cc(N[C@H]2CCN(C3CCN(c4cnc(Cl)cn4)CC3)C2=O)c(F)cc1S(C)(=O)=O -US04296200,1,O=C(O)c1cc(O)c2ccccc2c1O.OCC(Br)CBr>>O=C(O)c1cc(OCC(Br)CBr)c2ccccc2c1O -US04818766,6,COC(=O)C1=C(C)NC(C)=C(C(=O)OCCOc2ccc(OCCNC(=O)OC(C)(C)C)cc2)C1c1cccc([N+](=O)[O-])c1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCOc2ccc(OCCN)cc2)C1c1cccc([N+](=O)[O-])c1 -US06057335,7,C=Cc1ccc(-c2cc(NC(=O)C3Cc4ccccc4C3)n[nH]2)cc1>>CCc1ccc(-c2cc(NC(=O)C3Cc4ccccc4C3)n[nH]2)cc1 -US09049878B2,2,CC(C)(CO)C(=O)O.NC1CCCC1>>CC(C)(CO)C(=O)NC1CCCC1 -US05578620,9,[N-]=[N+]=NCC(O)COCCCCCc1ccccc1>>NCC(O)COCCCCCc1ccccc1 -US07910740B2,4,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)CBr.COc1cc(NC(N)=S)ccc1-n1cnc(C)c1>>COc1cc(Nc2nc([C@H](CC(C)C)NC(=O)OC(C)(C)C)cs2)ccc1-n1cnc(C)c1 -US06939886B2,1,BrCc1ccccc1.CCCCCc1c(-c2ccc3c(Br)c(OCC#N)ccc3c2)[nH]c2ccccc12>>CCCCCc1c(-c2ccc3c(Br)c(OCC#N)ccc3c2)n(Cc2ccccc2)c2ccccc12 -US20040127492A1,1,CC(C)(C)OC(=O)NCCBr.COC(=O)c1[nH]nc2c1CCc1cc(OC)c(Br)cc1-2>>COC(=O)c1c2c(nn1CCNC(=O)OC(C)(C)C)-c1cc(Br)c(OC)cc1CC2 -US20140303224A1,3,CC1(C)OB(c2cccc3c2CCC3=O)OC1(C)C.COc1ccc(Cl)c([N+](=O)[O-])c1>>COc1ccc(-c2cccc3c2CCC3=O)c([N+](=O)[O-])c1 -US07314877B2,7,O=C(O)c1cc(-c2ccc3c(c2)CCO3)nn(Cc2ccccc2Cl)c1=O>>O=c1c(CO)cc(-c2ccc3c(c2)CCO3)nn1Cc1ccccc1Cl -US05972978,1,ClCc1ccc(-c2ccccc2)cc1.c1ccc2c(c1)[nH]c1ccccc12>>c1ccc(-c2ccc(Cn3c4ccccc4c4ccccc43)cc2)cc1 -US20080153813A1,1,CC(C)(C)OC(=O)NCCCN.Clc1ccc2ncc(Br)n2n1>>CC(C)(C)OC(=O)NCCCNc1ccc2ncc(Br)n2n1 -US20010053851A1,6,COC(=O)C(CC1CCCC1)c1ccc(C#Cc2cncnc2)cc1>>O=C(O)C(CC1CCCC1)c1ccc(C#Cc2cncnc2)cc1 -US20040002524A1,2,COc1ccc(Nc2ccccc2N)cc1.O=C(O)c1sccc1Br>>COc1ccc(Nc2ccccc2NC(=O)c2sccc2Br)cc1 -US20020094989A1,1,BrCc1ccccc1.O=C(O)CC1CCC1>>O=C(CC1CCC1)OCc1ccccc1 -US20090317359A1,6,COc1ccc2nc(Nc3ccc(Br)cc3)ncc2c1>>Oc1ccc2nc(Nc3ccc(Br)cc3)ncc2c1 -US20070293521A1,1,Fc1cnc(Cl)nc1Nc1ccc2c(c1)OCCO2.Nc1cccc(C(F)(F)F)c1>>Fc1cnc(Nc2cccc(C(F)(F)F)c2)nc1Nc1ccc2c(c1)OCCO2 -US20130172317A1,6,COC(=O)[C@@H](C)Cn1c(=O)[nH]c(=Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cc2)c1=O>>C[C@@H](Cn1c(=O)[nH]c(=Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O -US08598173B2,2,CCOC(=O)Nc1nc2ccc(C)cc2nc1OC.Cc1cccc(C)c1N1CCNCC1>>COc1nc2cc(C)ccc2nc1NC(=O)N1CCN(c2c(C)cccc2C)CC1 -US04771046,9,CC(C)(C)OC(=O)N1CCC(=O)C1.NO>>CC(C)(C)OC(=O)N1CCC(=NO)C1 -US20140024650A1,1,Oc1ccc(Br)c(F)c1.c1cn[nH]c1>>Oc1ccc(-n2cccn2)c(F)c1 -US08697725B2,1,Brc1cn[nH]c1.ClCCBr>>ClCCn1cc(Br)cn1 -US20030009056A1,2,NC(c1ccccc1)c1ccccc1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NC(c1ccccc1)c1ccccc1 -US07427615B2,2,CC(C)(C)OC(=O)N1CCCC(C(=O)O)C1.Nc1ccccc1>>CC(C)(C)OC(=O)N1CCCC(C(=O)Nc2ccccc2)C1 -US20150087646A1,6,COC(=O)c1ccc(-n2nc(-c3cc(CNC(=O)C(F)(F)F)ccc3Cl)[nH]c2=O)cc1>>COC(=O)c1ccc(-n2nc(-c3cc(CN)ccc3Cl)[nH]c2=O)cc1 -US20030171360A1,7,CCOC(=O)N1CCC(Nc2ccccc2[N+](=O)[O-])CC1>>CCOC(=O)N1CCC(Nc2ccccc2N)CC1 -US05051422,6,COc1ccccc1N1CCN(Cc2ccccc2)C(CNC(=O)c2ccc(NS(C)(=O)=O)cc2)C1>>COc1ccccc1N1CCNC(CNC(=O)c2ccc(NS(C)(=O)=O)cc2)C1 -US07491819B1,7,N#Cc1cc(F)ccc1-n1cncn1>>NCc1cc(F)ccc1-n1cncn1 -US20120302547A1,3,C#C[Si](C)(C)C.COC(=O)c1sc(-c2ccc(Cl)cc2)cc1Br>>COC(=O)c1sc(-c2ccc(Cl)cc2)cc1C#C[Si](C)(C)C -US05407945,1,CCC1(c2cc(O)cc(F)c2)CCOC(C)C1.Cn1c(=O)ccc2cc(CBr)ccc21>>CCC1(c2cc(F)cc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOC(C)C1 -US08163752B2,2,CC(C)(C)OC(=O)CN1CC(CCCC(=O)[O-])c2c(N)cccc21>>CC(C)(C)OC(=O)CN1CC2CCCC(=O)Nc3cccc1c32 -US20140296252A1,6,Cc1nc(-n2nc(C(C)(C)COCc3ccccc3)[nH]c2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1>>Cc1nc(-n2nc(C(C)(C)CO)[nH]c2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1 -US20050250784A1,2,COC(=O)c1cnc(N2CCNCC2)s1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cnc(N2CCN(S(=O)(=O)c3ccc(C)cc3)CC2)s1 -US07915428B2,1,CCCCC(CC)CBr.COC(=O)CCCCCNc1ccccc1>>CCCCC(CC)CN(CCCCCC(=O)OC)c1ccccc1 -US08673942B2,6,CCOC(=O)CC1CN=C(c2cc3cc(Oc4ccc(S(C)(=O)=O)cn4)cc(OC(C)C)c3[nH]2)S1>>CC(C)Oc1cc(Oc2ccc(S(C)(=O)=O)cn2)cc2cc(C3=NCC(CC(=O)O)S3)[nH]c12 -US06670386B2,1,COC(=O)[C@@H]1[C@@H](O)CCN1C(=O)OC(C)(C)C.O=C(O)c1ccccc1>>COC(=O)[C@@H]1[C@H](OC(=O)c2ccccc2)CCN1C(=O)OC(C)(C)C -US20110123555A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C[C@H](N)c1ccccc1>>COC(=O)C[C@H](NC(=O)OC(C)(C)C)c1ccccc1 -US08242279B2,2,CNC(=O)c1cc(C#N)cc(C)c1N.O=C(O)c1cc(Br)nn1-c1ncccc1Cl>>CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl -US20050182040A1,6,NC(=O)c1ccc(NC2CCN(Cc3ccccc3)CC2)cc1>>NC(=O)c1ccc(NC2CCNCC2)cc1 -US20100145047A1,2,CCn1c(C(=O)Nc2ccc(N3CCNCC3)cc2)cc2c(Cl)c(Cl)ccc21.O=C(O)CC1SC(=O)NC1=O>>CCn1c(C(=O)Nc2ccc(N3CCN(C(=O)CC4SC(=O)NC4=O)CC3)cc2)cc2c(Cl)c(Cl)ccc21 -US20080306120A1,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1ncc(Br)cn1>>CC(C)(C)OC(=O)N1CCN(c2ncc(Br)cn2)CC1 -US08471005B2,1,CN(c1ccccc1-c1cc(OCOCC[Si](C)(C)C)c2cnc(O)nn12)S(C)(=O)=O.COc1cc(C2CCN(CC(N)=O)CC2)ccc1N>>COc1cc(C2CCN(CC(N)=O)CC2)ccc1Nc1ncc2c(OCOCC[Si](C)(C)C)cc(-c3ccccc3N(C)S(C)(=O)=O)n2n1 -US20070155716A1,1,Cc1cnccc1N.Fc1ccc(Cl)cc1-c1nc(I)c2c(n1)CCCC2>>Cc1cnccc1Nc1nc(-c2cc(Cl)ccc2F)nc2c1CCCC2 -US08486950B2,2,Nc1ccnc(Br)c1.O=C(Cl)c1c(Cl)cccc1Cl>>O=C(Nc1ccnc(Br)c1)c1c(Cl)cccc1Cl -US05068064,1,N#CCCl.c1ccc(CC2CCNCC2)cc1>>N#CCN1CCC(Cc2ccccc2)CC1 -US20120040942A1,2,CCOC(=O)c1c(C)nc2ncccc2c1N1CCCCC1.NCc1cccc(C(F)(F)F)c1>>Cc1nc2ncccc2c(N2CCCCC2)c1C(=O)NCc1cccc(C(F)(F)F)c1 -US20030203889A1,1,O=S(=O)(c1ccc(Br)cc1)C1CCN(CCc2ccc(F)cc2F)CC1.c1nc[nH]n1>>O=S(=O)(c1ccc(-n2cncn2)cc1)C1CCN(CCc2ccc(F)cc2F)CC1 -US20090215827A1,1,COC(=O)c1ccc2ccccc2c1O.FC(F)(F)c1ccc(CBr)cc1>>COC(=O)c1ccc2ccccc2c1OCc1ccc(C(F)(F)F)cc1 -US06956129B2,3,CC(=O)OC(C)=O.O=Cc1ccc(F)cc1F>>O=C(O)C=Cc1ccc(F)cc1F -US20040014753A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CCCC(=O)N1>>COC(=O)C1CCCC(=O)N1C(=O)OC(C)(C)C -US08241575B2,2,C=C(C)C(=O)Cl.C=CCCCCO>>C=CCCCCOC(=O)C(=C)C -US20090270473A1,7,CCCCc1nc(Cl)c(C=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CNC(=O)OC(C)(C)C)cc1>>CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CNC(=O)OC(C)(C)C)cc1 -US20040058903A1,2,Nc1ccc(CCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1.O=C(O)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(CCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1 -US20150266897A1,6,COC(=O)[C@@H]1C[C@@H](OCc2cn(CCCCCOC(C)=O)nn2)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@@H](OCc2cn(CCCCCO)nn2)CN1C(=O)OC(C)(C)C -US05891909,1,COc1ccccc1S(=O)(=O)Oc1cc(C)cc(OCCC=O)c1.NNC(N)=S>>COc1ccccc1S(=O)(=O)Oc1cc(C)cc(OCCC=NNC(N)=S)c1 -US07625893B2,2,CC(=O)Cl.COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)C[C@@H](CO)[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)C[C@@H](COC(C)=O)[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21 -US07612067B2,3,CCC(CC)c1cc(C)nn2c(-c3sc(I)cc3OC)c(C)nc12.[Zn+]c1nccs1>>CCC(CC)c1cc(C)nn2c(-c3sc(-c4nccs4)cc3OC)c(C)nc12 -US20090099205A1,7,CC(CCNC(=O)OC(C)(C)C)N1CCC(N2C(=O)N(c3ccccc3[N+](=O)[O-])C[C@H]2c2ccccc2)CC1>>CC(CCNC(=O)OC(C)(C)C)N1CCC(N2C(=O)N(c3ccccc3N)C[C@H]2c2ccccc2)CC1 -US05707544,1,O=C(O)c1ccc(N=Nc2ccc([N+](=O)[O-])cc2)cc1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OC(=O)c2ccc(N=Nc3ccc([N+](=O)[O-])cc3)cc2)cc1 -US08129396B2,2,CC(C)(C)OC(=O)NCC(=O)O.NC(=O)C(=C1Nc2ccc(N)cc2S1)c1nccc(C(F)(F)F)n1>>CC(C)(C)OC(=O)NCC(=O)Nc1ccc2c(c1)SC(=C(C(N)=O)c1nccc(C(F)(F)F)n1)N2 -US06051712,1,CC(C)(C)OC(=O)N1CCC(c2ccc(F)cc2)C(O)C1.N#Cc1ccccc1CBr>>CC(C)(C)OC(=O)N1CCC(c2ccc(F)cc2)C(OCc2ccccc2C#N)C1 -US04854962,2,Cc1nc(N)nc2c1CCO2.Cn1nnc2c(S(=O)(=O)N=C=O)cccc21>>Cc1nc(NC(=O)NS(=O)(=O)c2cccc3c2nnn3C)nc2c1CCO2 -US20110269741A1,1,CCOC(=O)C(=CN[C@@H](C(C)C)C(C)(C)O[SiH2]C(C)(C)C)C(=O)c1cc(Cc2cccc(Cl)c2F)nc(Cl)c1Cl>>CCOC(=O)c1cn([C@@H](C(C)C)C(C)(C)O[SiH2]C(C)(C)C)c2c(Cl)nc(Cc3cccc(Cl)c3F)cc2c1=O -US20020137755A1,1,Brc1ncc(-c2ccccc2)s1.Nc1ccncn1>>c1ccc(-c2cnc(Nc3ccncn3)s2)cc1 -US09062052B2,6,COC(=O)c1nc2ccc(O)cc2o1>>O=C(O)c1nc2ccc(O)cc2o1 -US20080090863A1,7,COC(=O)c1ccnc(Cl)c1>>OCc1ccnc(Cl)c1 -US20060111351A1,6,CC(C)(C)OC(=O)n1c(-c2ccc(S(=O)(=O)Nc3ccc(Cl)cc3C(=O)c3ccncc3)cc2)cc2ccccc21>>O=C(c1ccncc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(-c2cc3ccccc3[nH]2)cc1 -US05153227,9,O=S(=O)(Cl)c1ccc(I)cc1>>O=S([O-])c1ccc(I)cc1 -US20150051197A1,1,FC1(F)Oc2ccc(Br)cc2O1.O=S1(=O)CCN2C(=N1)C1(c3ccc(O)cc3)CCC2CC1>>O=S1(=O)CCN2C(=N1)C1(c3ccc(Oc4ccc5c(c4)OC(F)(F)O5)cc3)CCC2CC1 -US07572809B2,2,CN1CCNCC1.Cc1cc(Nc2cc3cc(C(=O)O)ccc3c(OC(C)C)n2)n[nH]1>>Cc1cc(Nc2cc3cc(C(=O)N4CCN(C)CC4)ccc3c(OC(C)C)n2)n[nH]1 -US20100168418A1,1,CCOC(=O)C1(CCCOS(C)(=O)=O)CCN(C(=O)OC(C)(C)C)CC1.COc1ccc2c(C)cc(=O)[nH]c2c1>>CCOC(=O)C1(CCCn2c(=O)cc(C)c3ccc(OC)cc32)CCN(C(=O)OC(C)(C)C)CC1 -US03991190,2,Nc1nc(Cl)cc(Cl)n1.O=CO>>O=CNc1nc(Cl)cc(Cl)n1 -US20080045546A1,2,Nc1cccc2c1C[C@H](O)CC2.O=C(O)c1ccc(-c2ccc(C(F)(F)F)cc2)cn1>>O=C(Nc1cccc2c1C[C@H](O)CC2)c1ccc(-c2ccc(C(F)(F)F)cc2)cn1 -US05747487,7,O=C(c1ccc([N+](=O)[O-])cc1)N1CCc2ccccc2-c2ccccc21>>Nc1ccc(C(=O)N2CCc3ccccc3-c3ccccc32)cc1 -US20060155121A1,7,CC(=O)Nc1c(C)cc([N+](=O)[O-])cc1C>>CC(=O)Nc1c(C)cc(N)cc1C -US20140329804A1,1,CC(=O)N1CCc2nc3ccc(C#N)cc3c(Cl)c2C1.COc1ccc(CN)cc1Cl>>COc1ccc(CNc2c3c(nc4ccc(C#N)cc24)CCN(C(C)=O)C3)cc1Cl -US20090131483A1,3,C=CC(=O)OC.Cc1c(I)cc(C(=O)NCc2cc(C3CC3)no2)c(=O)n1-c1cccc(C(F)(F)F)c1>>COC(=O)C=Cc1cc(C(=O)NCc2cc(C3CC3)no2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C -US08063234B2,7,N#CC1CC1C(=O)c1ccc(Cl)cc1F>>N#CC1CC1C(O)c1ccc(Cl)cc1F -US20010036958A1,2,Cc1noc(N)c1Br.O=S(=O)(Cl)c1cc(Cl)ccc1Cl>>Cc1noc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1Br -US20010036958A1,2,Cc1noc(N)c1Br.O=S(=O)(Cl)c1cc(Cl)ccc1Cl>>Cc1noc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1Br -US08106215B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(F)(F)C[C@@H]3[C@H]2CN)c1.O=C(O)c1cccc2c1OCCO2>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(F)(F)C[C@@H]3[C@H]2CNC(=O)c2cccc3c2OCCO3)c1 -US20130184313A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCCC1CCNC1>>CC(C)(C)OC(=O)N1CCC(CCCO)C1 -US20120295897A1,2,C[C@@H](CO)OCOCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](C)OCOCc2ccccc2)cc1 -US05962473,2,CN1CCC(c2c[nH]c3ccc(N)cc23)CC1.O=C(O)C1CCCC1>>CN1CCC(c2c[nH]c3ccc(NC(=O)C4CCCC4)cc23)CC1 -US20150005282A1,1,COC(=O)C[C@@H]1COc2cc(OCc3cccc(-c4c(C)cc(O)cc4C)c3)ccc21.CS(=O)(=O)OC1CCCC1>>COC(=O)C[C@@H]1COc2cc(OCc3cccc(-c4c(C)cc(OC5CCCC5)cc4C)c3)ccc21 -US07638648B2,6,CCOC(=O)C(C)(C)c1cccc(C#Cc2ccc(CC(=O)OC)cc2)c1>>COC(=O)Cc1ccc(C#Cc2cccc(C(C)(C)C(=O)O)c2)cc1 -US20140249154A1,4,CCOC(=O)C(Br)C(=O)c1ccccn1.NC(=S)Nc1ncccn1>>CCOC(=O)c1sc(Nc2ncccn2)nc1-c1ccccn1 -US20100210592A1,1,Cc1cc(Br)cnc1O.OC1CCOCC1>>Cc1cc(Br)cnc1OC1CCOCC1 -US09000025B2,1,CC(C)n1cc(Br)cn1.CCOC(=O)c1cccc(Sc2c(C)[nH]c3cc(Cl)ccc23)c1>>CCOC(=O)c1cccc(Sc2c(C)n(-c3cnn(C(C)C)c3)c3cc(Cl)ccc23)c1 -US20090156642A1,2,CCOC(=O)c1cc(Sc2ccc(Cl)nc2)n(-c2cccc(F)c2Cl)n1.CN>>CNC(=O)c1cc(Sc2ccc(Cl)nc2)n(-c2cccc(F)c2Cl)n1 -US20140088076A1,9,CC(=O)c1cc(Cl)ncc1C#Cc1cc(F)ccc1C.NO>>CC(=NO)c1cc(Cl)ncc1C#Cc1cc(F)ccc1C -US07598393B2,1,CC(C)(C)c1nc2cc(Br)cnc2n1CC1CCOCC1.CC(C)S>>CC(C)Sc1cnc2c(c1)nc(C(C)(C)C)n2CC1CCOCC1 -US20140155391A1,6,COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NC(=O)CC(=O)N1C[C@@H](C)N(C(=O)OC(C)(C)C)C[C@@H]1C>>COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NC(=O)CC(=O)N1C[C@@H](C)NC[C@@H]1C -US20140142085A1,2,NC(=O)c1cccc(-c2cccnc2[C@@H](N)Cc2cc(F)cc(F)c2)c1.O=C(O)Cc1cccc(Cl)c1>>NC(=O)c1cccc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cc2cccc(Cl)c2)c1 -US04309566,1,NC(=O)CCl.O=C(O)c1c(Cl)ccc(Cl)c1Cl>>NC(=O)COC(=O)c1c(Cl)ccc(Cl)c1Cl -US08273773B2,1,CCOC(=O)c1ccc(Cl)nc1.NC1CC1>>CCOC(=O)c1ccc(NC2CC2)nc1 -US06936632B2,7,Cc1c(C(=O)C(C)C)c(-c2ccccc2)c2n1CCC2>>Cc1c(CC(C)C)c(-c2ccccc2)c2n1CCC2 -US20050277630A1,9,CCCC(=O)OC[C@H]1CN(c2ccc3c(c2)CCC(N=[N+]=[N-])C(=O)N3)C(=O)O1>>CCCC(=O)OC[C@H]1CN(c2ccc3c(c2)CCC(N)C(=O)N3)C(=O)O1 -US08829026B2,1,COC(=O)c1ccc(S(=O)(=O)NCc2ccc3occc3c2)cc1.Fc1ncc(Cl)cc1Cl>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc3occc3c2)c2ncc(Cl)cc2Cl)cc1 -US08952163B2,6,COC(=O)c1ccc2c(n1)CCN(Cc1ccccc1)C2>>COC(=O)c1ccc2c(n1)CCNC2 -US20080070895A1,3,CC1(C)OB(c2ccc3c(c2)C[C@H]2CC[C@@H](C3)[C@]23CN(CC(F)(F)F)S(=O)(=O)N3)OC1(C)C.Fc1ccc(-n2cnc(Br)c2)cc1>>O=S1(=O)N[C@]2(CN1CC(F)(F)F)[C@H]1CC[C@@H]2Cc2cc(-c3cn(-c4ccc(F)cc4)cn3)ccc2C1 -US05475106,2,CC(C)(C)OC(=O)CN(C(=O)CN)c1ccccc1-c1ccccc1.Cc1cccc(N=C=O)c1>>Cc1cccc(NC(=O)NCC(=O)N(CC(=O)OC(C)(C)C)c2ccccc2-c2ccccc2)c1 -US04349685,2,CCCCN=C=O.O=c1oc2ccc(O)cc2s1>>CCCCNC(=O)Oc1ccc2oc(=O)sc2c1 -US08557805B2,9,COCc1ccc(Oc2cc(OC3CCOCC3)c3[nH]c(C4=NCC(CC(=O)O)S4)cc3c2)cn1.N>>COCc1ccc(Oc2cc(OC3CCOCC3)c3[nH]c(C4=NCC(CC(N)=O)S4)cc3c2)cn1 -US05962453,8,Nc1nc(-c2cc(Cl)ccc2Cl)nc(N2CCSCC2)n1.OO>>Nc1nc(-c2cc(Cl)ccc2Cl)nc(N2CCS(=O)CC2)n1 -US07122550B2,1,Clc1cncc(Cl)n1.N[C@@H](CO)c1ccccc1>>OC[C@H](Nc1cncc(Cl)n1)c1ccccc1 -US05006548,1,O=C(C=Cc1cccs1)Nc1ccccc1C(=O)O.O=C1OC(Br)c2ccccc21>>O=C(C=Cc1cccs1)Nc1ccccc1C(=O)OC1OC(=O)c2ccccc21 -US04661515,6,CC(=O)SCC(C)C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1>>CC(=O)SCC(C)C(=O)N(CC(=O)O)C1CCCC1 -US06107251,6,CCOc1oc(-c2c(Cl)cccc2OCc2ccccc2)nc1C(C)C>>CCOc1oc(-c2c(O)cccc2Cl)nc1C(C)C -US20150057260A1,9,CCOC(=O)c1cc(-c2ccc(C)nc2)cc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1.N>>Cc1ccc(-c2cc(C(N)=O)nc(-c3cccc(C#C[C@]4(O)CCN(C)C4=O)c3)c2)cn1 -US06515011B2,6,CC(C)(C)OC(=O)NCCc1ccccc1CNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCCc1ccccc1CN -US20090325930A1,7,COc1cccc(N2CCC(c3ccccc3[N+](=O)[O-])C2)c1>>COc1cccc(N2CCC(c3ccccc3N)C2)c1 -US20150210720A1,7,CN1CCN(CCn2ncc3cc([N+](=O)[O-])ccc32)CC1>>CN1CCN(CCn2ncc3cc(N)ccc32)CC1 -US20030153606A1,1,CC(C)I.Cc1ccc2c(c1)NCCC2>>Cc1ccc2c(c1)N(C(C)C)CCC2 -US08217032B2,6,COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3cccc(F)c3F)ccc2c1>>O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2cccc(F)c2F)ccc2cc(O)ccc12 -US20060100215A1,9,CON=C1CN(C(=O)OCc2ccccc2)CC1CN=[N+]=[N-]>>CON=C1CN(C(=O)OCc2ccccc2)CC1CN -US08592452B2,9,N.O=C(O)c1cc(F)c(F)cc1Cl>>NC(=O)c1cc(F)c(F)cc1Cl -US08158638B2,6,CCNCCc1cc2nn(Cc3ncc(C)c(OC)c3C)nc3c-2c1CSN=C3NC(=O)OC(C)(C)C>>CCNCCc1cc2nn(Cc3ncc(C)c(OC)c3C)nc3c-2c1CSN=C3N -US20020193402A1,7,N#C[C@@H]1C[C@@]2(c3ccccc3)C(=O)CC[C@@H]1N2Cc1ccccc1>>N#C[C@@H]1C[C@@]2(c3ccccc3)[C@H](O)CC[C@@H]1N2Cc1ccccc1 -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.O=Cc1cccc2c1OCCO2>>COc1cc(O)c2c(c1C(=O)NCc1cccc3c1OCCO3)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US04721797,2,COCC(=O)Cl.Cc1cccc(C)c1NC1CCOC1=O>>COCC(=O)N(c1c(C)cccc1C)C1CCOC1=O -US08217067B2,9,[N-]=[N+]=NCc1cc(F)cnc1Cl>>NCc1cc(F)cnc1Cl -US04933355,3,CCOC(=O)C(=O)c1csc(NC(=O)Nc2c(C)cccc2C)n1.O=C(O)CN1C(=O)CSC1=S>>CCOC(=O)C(=C1SC(=S)N(CC(=O)O)C1=O)c1csc(NC(=O)Nc2c(C)cccc2C)n1 -US20140057926A1,6,CC(C)S(=O)(=NC#N)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1>>CC(C)S(=O)(=NC#N)c1ccc(CN)cc1 -US20130045986A1,5,Brc1ccc2oc(C3CCNCC3)nc2c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC(c2nc3cc(Br)ccc3o2)CC1 -US20100279936A1,1,C[C@@H](N)c1cccc2ccccc12.O=Cc1ccc(C#CCCO)cc1>>C[C@@H](NCc1ccc(C#CCCO)cc1)c1cccc2ccccc12 -US20010036946A1,6,O=c1[nH]c2ccccc2c(=O)n1C1CCN(Cc2ccccc2)CC1>>O=c1[nH]c2ccccc2c(=O)n1C1CCNCC1 -US05071846,2,Fc1ccc(Cn2c(NC3CCN(CCN=C=S)C3)nc3ccccc32)cc1.Nc1ccncc1N>>Nc1ccncc1NC(=S)NCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)C1 -US20110281854A1,1,O=C1COc2ccc(Br)nc2N1.c1ccc2c(c1)CCC21COCCN1>>O=C1COc2ccc(N3CCOCC34CCc3ccccc34)nc2N1 -US20150191439A1,1,NC12CC3CC(CC(C3)C1)C2.O=Cc1ccc(N2CCCC2=O)cc1>>O=C1CCCN1c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1 -US06358972B1,3,CN1CCC(c2c[nH]c3ccc(B(O)O)cc23)CC1.Clc1nc2ccccc2[nH]1>>CN1CCC(c2c[nH]c3ccc(-c4nc5ccccc5[nH]4)cc23)CC1 -US20110105462A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1COc2c(F)cc(F)cc2O1>>Cc1ccc(S(=O)(=O)OCC2COc3c(F)cc(F)cc3O2)cc1 -US20070179185A1,1,CCI.Fc1c(OC(F)(F)F)cccc1C1CCNCC1>>CCN1CCC(c2cccc(OC(F)(F)F)c2F)CC1 -US08586550B2,1,COCCBr.OC[C@H]1O[C@@H](c2cc(Cc3ncc(-c4ccco4)s3)c(Cl)cc2O)[C@H](O)[C@@H](O)[C@@H]1O>>COCCOc1cc(Cl)c(Cc2ncc(-c3ccco3)s2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O -US05439925,1,CC(C)(C)c1cc(C(=O)OCc2ccccc2)ccc1O.CC(C)I>>CC(C)Oc1ccc(C(=O)OCc2ccccc2)cc1C(C)(C)C -US05977105,1,O=C(c1ccccc1)c1ccc(O)cc1.OC(CCl)CCc1cccnc1>>O=C(c1ccccc1)c1ccc(OCC(O)CCc2cccnc2)cc1 -US04977167,8,O=C(OO)c1cccc(Cl)c1.O=C1CCCN1C(=O)NCCSc1ccccn1>>O=C1CCCN1C(=O)NCCS(=O)c1ccccn1 -US20080176830A1,1,CC(C)(C)[Si](C)(C)OCC=O.NCc1cc(-c2ccc(C(F)(F)F)cc2)ccc1[N+](=O)[O-]>>CC(C)(C)[Si](C)(C)OCCNCc1cc(-c2ccc(C(F)(F)F)cc2)ccc1[N+](=O)[O-] -US20040097507A1,2,Cc1onc(-c2ncc(Cl)cc2Cl)c1C(=O)O.NC1CCCC(CNC(=O)OCc2ccccc2)C1>>Cc1onc(-c2ncc(Cl)cc2Cl)c1C(=O)NC1CCCC(CNC(=O)OCc2ccccc2)C1 -US20100298324A1,2,COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc1.NCc1ccc(Cl)cc1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)ccc3c2=O)nc1 -US20150080549A1,6,CC(C)(C)OC(=O)N[C@@H](CSSC(C)(C)C)C(=O)O[C@@H]1[C@@H](COP(=O)(O)O[C@H]2C[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(=O)(O)O)O[C@@H](n2cnc3c(N)ncnc32)[C@@H]1O>>CC(C)(C)SSC[C@H](N)C(=O)O[C@@H]1[C@@H](COP(=O)(O)O[C@H]2C[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(=O)(O)O)O[C@@H](n2cnc3c(N)ncnc32)[C@@H]1O -US08680091B2,7,CC(C)(C)CCNC(=O)Cc1ccc(C#N)cc1>>CC(C)(C)CCNC(=O)Cc1ccc(CN)cc1 -US20100210642A1,3,C#Cc1ccc(N)nc1.Clc1ccc(-c2cc(C3CC3)c3ncc(I)n3c2)cc1>>Nc1ccc(C#Cc2cnc3c(C4CC4)cc(-c4ccc(Cl)cc4)cn23)cn1 -US06284755B1,9,Fc1cc(C(Cl)c2ccccn2)ccc1Br>>Fc1cc(Cc2ccccn2)ccc1Br -US20090325930A1,7,COc1ccc(-c2nc3ccc(OC)cc3s2)c([N+](=O)[O-])c1>>COc1ccc(-c2nc3ccc(OC)cc3s2)c(N)c1 -US04495182,2,CS(=O)(=O)Cl.Nc1nc(C(=NOCC(=O)O)C(=O)O)ns1>>CS(=O)(=O)OC(=O)C(=NOCC(=O)O)c1nsc(N)n1 -US07521462B2,6,CC(C)CCN(Cc1cc2ccccc2o1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CCN(Cc1cc2ccccc2o1)C1CCNCC1 -US20140235628A1,2,CS(=O)(=O)Cl.Cc1c(C(=O)CC2(O)CCN(C(=O)OC(C)(C)C)CC2)ccc2c1COC2=O>>Cc1c(C(=O)CC2(OS(C)(=O)=O)CCN(C(=O)OC(C)(C)C)CC2)ccc2c1COC2=O -US07645760B2,2,CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)O.OC[C@@H]1CN(Cc2ccc(F)cc2)CCN1>>CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1CO -US04009275,1,C=CCc1cc(F)ccc1O.O=C1NCN(c2ccccc2)C12CCN(CCCCl)CC2>>C=CCc1cc(F)ccc1OCCCN1CCC2(CC1)C(=O)NCN2c1ccccc1 -US20110112162A9,1,BrCc1cccc(OCc2ccccc2)c1.O=C1Nc2ccccc2C12COc1cc3c(cc12)CCO3>>O=C1N(Cc2cccc(OCc3ccccc3)c2)c2ccccc2C12COc1cc3c(cc12)CCO3 -US20140140956A1,1,CC(C)N.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCBr)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCNC(C)C)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1 -US04234585,1,Cc1cc(=O)[nH]c2ccc(O)cc12.Cc1ccc(CN2CCN(CCCCl)CC2)cc1>>Cc1ccc(CN2CCN(CCCOc3ccc4[nH]c(=O)cc(C)c4c3)CC2)cc1 -US20150157622A1,1,COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](O)[C@@H]1OC.O=Cc1ccc(C(=O)O)cc1>>COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2ccc(C=O)cc2)[C@@H]1OC -US05290949,7,CCC1=C(c2cccc(F)c2)C(=O)N(c2ccc(Cl)c(C(F)(F)F)c2)C1>>CCC1CN(c2ccc(Cl)c(C(F)(F)F)c2)C(=O)C1c1cccc(F)c1 -US04169141,1,CC(C)(C)OC(=O)NCC(=O)NCC(=O)O.Oc1cc(Cl)c(Cl)cc1Cl>>CC(C)(C)OC(=O)NCC(=O)NCC(=O)Oc1cc(Cl)c(Cl)cc1Cl -US20140057893A1,1,CS(=O)(=O)c1ccc(Br)nc1.O=C(OCc1ccccc1)N1CCC([C@H]2C[C@H]2CCO)CC1>>CS(=O)(=O)c1ccc(OCC[C@@H]2C[C@@H]2C2CCN(C(=O)OCc3ccccc3)CC2)nc1 -US20050014804A1,6,CC(C)(C)OC(=O)NCC1(C(=O)O)CC12CCCCC2>>NCC1(C(=O)O)CC12CCCCC2 -US04285948,2,NC1=NCCCN1.O=C=Nc1c(Cl)cccc1Cl>>O=C(NC1=NCCCN1)Nc1c(Cl)cccc1Cl -US20130344030A1,3,C=CC1(C(=O)O)CCC(=O)CC1.C[C@H](c1ccc2ccc(Br)cc2n1)N(C)C(=O)OC(C)(C)C>>C[C@H](c1ccc2ccc(/C=C/C3(C(=O)O)CCC(=O)CC3)cc2n1)N(C)C(=O)OC(C)(C)C -US20150111891A1,2,Cc1cc2ccccc2c(Cl)c1[C@@H](O)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](O)c2c(C)cc3ccccc3c2Cl)cc1 -US20110105436A1,4,Cc1cccc(NC(N)=S)c1.O=C(CBr)c1ccncc1>>Cc1cccc(Nc2nc(-c3ccncc3)cs2)c1 -US05827865,6,CCOC(=O)C(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)OC>>COC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O -US20100041892A1,2,COCCOc1ccc(CCCN)c(Oc2ncc(C(F)(F)F)cc2Cl)c1.O=S(=O)(Cl)c1ccccc1Cl>>COCCOc1ccc(CCCNS(=O)(=O)c2ccccc2Cl)c(Oc2ncc(C(F)(F)F)cc2Cl)c1 -US06140338,1,O=C(NC1CC2CCCC(C1)N2)C1c2ccccc2Oc2ccccc21.O=CC1CCCCCCC1>>O=C(NC1CC2CCCC(C1)N2CC1CCCCCCC1)C1c2ccccc2Oc2ccccc21 -US20140135318A1,6,CCCCN(CCCC)C(=O)c1cn(CCN2CCN(C)CC2)c(-c2ccc(C(=O)OC)cc2C(=O)OCc2ccccc2)n1>>CCCCN(CCCC)C(=O)c1cn(CCN2CCN(C)CC2)c(-c2ccc(C(=O)OC)cc2C(=O)O)n1 -US07674811B2,1,CI.Cc1nn(-c2ccc(Sc3cccc(C4(C5=NC(C)C(C)O5)CCOCC4)c3)cc2)c(=O)[nH]1>>Cc1nn(-c2ccc(Sc3cccc(C4(C5=NC(C)C(C)O5)CCOCC4)c3)cc2)c(=O)n1C -US08288419B2,7,COC(=O)c1ccc(Cn2cc(NC(=O)OCc3ccccc3Cl)cn2)o1>>O=C(Nc1cnn(Cc2ccc(CO)o2)c1)OCc1ccccc1Cl -US04870082,1,NNC(=O)c1cccc([N+](=O)[O-])c1.O=Cc1ccc2ccccc2n1>>O=C(NN=Cc1ccc2ccccc2n1)c1cccc([N+](=O)[O-])c1 -US20020006932A1,1,CNC.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)N(CCCO)CN2c1ccccc1>>CN(C)CCCN1CN(c2ccccc2)C2(CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)C1=O -US20150148327A1,1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cncc(N)c2)c1.O=CC(=O)O>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cncc(NCC(=O)O)c2)c1 -US20120059162A1,1,CC(C)(C)OC(=O)N(CC1CCOCC1)c1cc(Cl)nn2ccnc12.CCC(C)N>>CCC(C)Nc1cc(N(CC2CCOCC2)C(=O)OC(C)(C)C)c2nccn2n1 -US20060148858A1,2,CS(=O)(=O)Cl.OCCCCc1cc(-c2ccc(C(F)(F)F)cc2)no1>>CS(=O)(=O)OCCCCc1cc(-c2ccc(C(F)(F)F)cc2)no1 -US20090182140A1,1,CCOC(=O)N1CCC(c2cc(Cl)n3nccc3n2)CC1.NCc1ccc(Cl)cc1Cl>>CCOC(=O)N1CCC(c2cc(NCc3ccc(Cl)cc3Cl)n3nccc3n2)CC1 -US20060257987A1,2,CCc1ccc(OCCC(C)O)c(C(=O)c2ccccc2)c1.CS(=O)(=O)Cl>>CCc1ccc(OCCC(C)OS(C)(=O)=O)c(C(=O)c2ccccc2)c1 -US20050043358A1,1,Fc1ccc2nccc(Cl)c2c1.OC[C@H](Cc1ccc(O)cc1)N(Cc1ccccc1)C[C@H](O)COc1ccccc1>>OC[C@H](Cc1ccc(Oc2ccnc3ccc(F)cc23)cc1)N(Cc1ccccc1)C[C@H](O)COc1ccccc1 -US05302724,2,CCc1ccc(S(N)(=O)=O)o1.O=C=Nc1ccc(Cl)cc1>>CCc1ccc(S(=O)(=O)NC(=O)Nc2ccc(Cl)cc2)o1 -US07238693B2,6,CCOc1ccccc1NC(=O)OC(C)(C)C>>CCOc1ccccc1N -US03932429,1,COc1cccc(C2(C(N)=O)CCC(=O)C(Br)C2)c1>>COc1cccc(C23CCC(=O)C(C2)NC3=O)c1 -US20020137747A1,2,CC(=O)Cl.Cc1ccc(N)cc1NC(=O)C(F)(F)F>>CC(=O)Nc1ccc(C)c(NC(=O)C(F)(F)F)c1 -US20140093453A1,6,CCN(CCOc1cccnc1F)CCN1C(=O)c2ccccc2C1=O>>CCN(CCN)CCOc1cccnc1F -US20090264405A1,1,FC(F)(F)c1ccc(N2CCNCC2)cc1.N#Cc1cc(Br)c2oc(-c3ccc(NC(=O)CBr)cc3)nc2c1>>N#Cc1cc(Br)c2oc(-c3ccc(NC(=O)CN4CCN(c5ccc(C(F)(F)F)cc5)CC4)cc3)nc2c1 -US20090197834A1,6,CCOC(=O)c1cn(C2CCCC2)c2cc(F)ccc2c1=O>>O=C(O)c1cn(C2CCCC2)c2cc(F)ccc2c1=O -US05670505,6,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)N1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccccc2)C1>>O=C([C@@H]1C[C@@H](O)CN1)N1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccccc2)C1 -US09115054B2,7,CCCCCC[C@@H]1CCc2cc(C3CCC(N)(C(=O)OC)C3)ccc2C1>>CCCCCC[C@@H]1CCc2cc(C3CCC(N)(CO)C3)ccc2C1 -US20070155808A1,6,COC(=O)CCc1ccc(OCc2ccc(CN(CCc3ccccc3)c3nc(-c4ccccc4)cs3)cc2)cc1>>O=C(O)CCc1ccc(OCc2ccc(CN(CCc3ccccc3)c3nc(-c4ccccc4)cs3)cc2)cc1 -US08101610B2,1,O=C(Nc1ccc(Cl)c(NC(=O)c2ccccc2)c1)c1ccc(Cl)nc1.OC1CCNCC1>>O=C(Nc1ccc(Cl)c(NC(=O)c2ccccc2)c1)c1ccc(N2CCC(O)CC2)nc1 -US20100004238A1,1,Cn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2cnn3ccccc23)c(Cl)c1>>Cn1ccc2ncnc(Nc3ccc(Oc4cnn5ccccc45)c(Cl)c3)c21 -US20120129811A1,1,CN1CCNCC1.O=[N+]([O-])c1cccc2[nH]c(Cl)nc12>>CN1CCN(c2nc3c([N+](=O)[O-])cccc3[nH]2)CC1 -US20090197915A1,1,CNCc1ccccc1.Cn1ccc2c1CCCC2CCCl>>CN(CCC1CCCc2c1ccn2C)Cc1ccccc1 -US04820332,7,Cc1nc2cccc([N+](=O)[O-])c2s1>>Cc1nc2cccc(N)c2s1 -US03978134,1,CCOCCCC(C)=CCBr.Oc1ccc2c(c1)OCO2>>CCOCCCC(C)=CCOc1ccc2c(c1)OCO2 -US05495046,1,CCCNCCC.ClCCCc1cc(Cl)ccc1OCCc1ccccc1>>CCCN(CCC)CCCc1cc(Cl)ccc1OCCc1ccccc1 -US06218376B1,3,CCc1cccc(Br)c1.CN(C)C=O>>CCc1cccc(C=O)c1 -US20110098272A1,6,CC(C)(C)OC(=O)N1CC(n2cnc(-c3ccc(F)cc3)c2-c2ccnc(N)n2)C1>>Nc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CNC2)n1 -US20150023913A1,3,COC(=O)C12CCC(Br)(CC1)CC2.c1ccccc1>>COC(=O)C12CCC(c3ccccc3)(CC1)CC2 -US20150284321A1,2,Nc1ccccc1NC(=O)Nc1ccccc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(Nc1ccccc1)Nc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 -US20070082908A1,1,Cc1[nH]c(=O)c2c(Cc3ccccc3Cl)c(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)nn2c1C.O=C(CBr)c1ccccc1>>Cc1c(C)n2nc(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)c(Cc3ccccc3Cl)c2c(=O)n1CC(=O)c1ccccc1 -US07557127B2,7,Cc1nc(NC2CCN(Cc3ccccc3)C2)ncc1C(=O)OCc1ccccc1>>Cc1nc(NC2CCN(Cc3ccccc3)C2)ncc1CO -US20080269170A1,1,CC(C)C=O.CN(C1CCNCC1)S(=O)(=O)c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1>>CC(C)CN1CCC(N(C)S(=O)(=O)c2ccc(Nc3nccc(Nc4ccc(F)cc4)n3)cc2)CC1 -US06271225B1,7,CCOC(=O)c1c(Nc2cc(Cl)c(Cl)cc2[N+](=O)[O-])sc2ccccc12>>CCOC(=O)c1c(Nc2cc(Cl)c(Cl)cc2N)sc2ccccc12 -US20100120739A1,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C(O)Cc1cc2cc(Br)cnc2cc1F>>Cn1cc(-c2cnc3cc(F)c(CC(=O)O)cc3c2)cn1 -US20100298293A1,1,C=CCC1CCCNC1=O.Nc1ccc(I)c(Cl)c1>>C=CCC1CCCN(c2ccc(N)cc2Cl)C1=O -US08796256B2,1,O=C1NC(=O)/C(=C/c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)S1.OC[C@H]1CN2CCC[C@H]2CO1>>O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1C[C@H]1CN2CCC[C@H]2CO1 -US20150152068A1,1,CI.COC(=O)[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@H](OC)CN1C(=O)OC(C)(C)C -US05262433,2,O=C(O)Cn1nnnc1-c1cccc(C(F)(F)F)c1.OCCO>>O=C(Cn1nnnc1-c1cccc(C(F)(F)F)c1)OCCO -US20140274907A1,2,C/C=C/C1=CN2C(=O)c3cc(OC)c(OCCCOc4cc5c(cc4OC)C(=O)N4C=C(/C=C/CNC(=O)[C@H](C)NC(=O)[C@@H](N)C(C)C)C[C@H]4C=N5)cc3N=C[C@@H]2C1.O=C(O)CCOCCOCCOCCOCCNC(=O)CI>>C/C=C/C1=CN2C(=O)c3cc(OC)c(OCCCOc4cc5c(cc4OC)C(=O)N4C=C(/C=C/CNC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCNC(=O)CI)C(C)C)C[C@H]4C=N5)cc3N=C[C@@H]2C1 -US20150065482A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCC(O)C(=O)O>>CC(C)(C)OC(=O)NCCC(O)C(=O)O -US06087357,1,Cc1ccc(C[C@@H]2CNCCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C.ClCc1ccccn1>>Cc1ccc(C[C@@H]2CN(Cc3ccccn3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C -US04404393,1,C#CCC(CCCC)(O[Si](C)(C)C)C(=C)F.CCCC[SnH](CCCC)CCCC>>C=C(F)C(C/C=C/[Sn](CCCC)(CCCC)CCCC)(CCCC)O[Si](C)(C)C -US20030092720A1,1,C1COCCN1.CC(C)c1csc(CCc2ccn3c(=O)cc(O)nc3c2)n1>>CC(C)c1csc(CCc2ccn3c(=O)cc(N4CCOCC4)nc3c2)n1 -US05103022,3,C1CCNC1.C=O.CCC(=O)c1cccc(C)c1C>>Cc1cccc(C(=O)C(C)CN2CCCC2)c1C -US05840724,1,BrC1CCCC1.COC(=O)c1ccc([N+](=O)[O-])c(O)c1>>COC(=O)c1ccc([N+](=O)[O-])c(OC2CCCC2)c1 -US20070032515A1,1,BrCCBr.COC(=O)c1cccc(OC(=O)c2ccccc2)c1O>>COC(=O)c1cccc(OC(=O)c2ccccc2)c1OCCBr -US20120283297A1,6,COC(=O)c1ccc(OC(C)C)c(C#N)c1>>CC(C)Oc1ccc(C(=O)O)cc1C#N -US07091214B2,7,CSCCCNc1c([N+](=O)[O-])cnc2cc(-c3ccccc3)ccc12>>CSCCCNc1c(N)cnc2cc(-c3ccccc3)ccc12 -US20140135318A1,6,CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)OCC)c(C)c1Cl>>CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)O)c(C)c1Cl -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nccn4CCCC(=O)OCC)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nccn4CCCC(=O)OCC)cc2)CCN3CC(C)C)cc1 -US20110112089A1,4,NC(=S)Nc1cccnc1.O=C(O)c1ccc(C(=O)CBr)cc1>>O=C(O)c1ccc(-c2csc(Nc3cccnc3)n2)cc1 -US20090215759A1,1,COc1cc(N)ccc1-n1cnc(C)c1.Cc1cc(Oc2ccc(F)cc2)nc(Cl)n1>>COc1cc(Nc2nc(C)cc(Oc3ccc(F)cc3)n2)ccc1-n1cnc(C)c1 -US20090318690A1,1,C1COCCN1.C=CCOc1cc(F)ccc1C(C)=O>>C=CCOc1cc(N2CCOCC2)ccc1C(C)=O -US06399629B1,9,CCOC(=O)[C@@H]1CC(CCCN=[N+]=[N-])CN1C(=O)OC(C)(C)C>>CCOC(=O)[C@@H]1CC(CCCN)CN1C(=O)OC(C)(C)C -US20100210641A1,3,COc1cc(B(O)O)ccn1.Clc1ccc2ncc(Br)n2c1>>COc1cc(-c2cnc3ccc(Cl)cn23)ccn1 -US08927536B2,3,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(B5OC(C)(C)C(C)(C)O5)cc4)CC3)n2CCS1.Cc1ccc(Cl)nn1>>Cc1ccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)nn1 -US20060084643A1,1,CC=O.COCC[C@H]1CN(C2=Nc3ccccc3Nc3sc(C(F)(F)F)nc32)CCN1>>CCN1CCN(C2=Nc3ccccc3Nc3sc(C(F)(F)F)nc32)C[C@@H]1CCOC -US07368593B1,1,BrCCc1ccccc1.O=C(O)/C=C/c1ccc(O)c(O)c1>>O=C(/C=C/c1ccc(O)c(O)c1)OCCc1ccccc1 -US20080004297A1,1,COc1ccc(N)cc1OC.Cc1nc(Cl)c2ccccc2n1>>COc1ccc(Nc2nc(C)nc3ccccc23)cc1OC -US09073894B2,1,C1CNC2(C1)COC2.CC1(C)O[C@H](c2ccc(-c3ccc(CCl)nc3)cc2)[C@@H](CF)N1C(=O)C(F)F>>CC1(C)O[C@H](c2ccc(-c3ccc(CN4CCCC45COC5)nc3)cc2)[C@@H](CF)N1C(=O)C(F)F -US06432950B1,1,Cc1cc2c(Cl)nc(-c3ccno3)nc2s1.NCCc1ccc2c(c1)OCO2>>Cc1cc2c(NCCc3ccc4c(c3)OCO4)nc(-c3ccno3)nc2s1 -US20150111869A1,3,Brc1ccc(Br)nc1.CCC(C)CC(=O)N(C)OC>>CCC(C)CC(=O)c1ccc(Br)cn1 -US20110144188A1,2,CCOC(=O)C(N)(CC)c1ccccc1.O=CO>>CCOC(=O)C(CC)(NC=O)c1ccccc1 -US05332734,5,Cc1cccc(NC(=O)[C@@H](N)C(C)C)c1C(=O)O.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>Cc1cccc(NC(=O)[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(C)C)c1C(=O)O -US20150210681A1,6,CCOC(=O)C(C)(C)c1ccc(-c2ccc(OCC3(C)COC3)cc2)cc1>>CC1(COc2ccc(-c3ccc(C(C)(C)C(=O)O)cc3)cc2)COC1 -US06313310B1,3,C#CC(O)c1cccc(O)c1.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CC(O)c3cccc(O)c3)c21 -US20140213589A1,3,C#Cc1ccccn1.COc1cc(Br)ccc1Oc1ccc([N+](=O)[O-])cc1F>>COc1cc(C#Cc2ccccn2)ccc1Oc1ccc([N+](=O)[O-])cc1F -US20110002855A1,1,Brc1ccccc1.CC(C)(C)OC(=O)N1CCc2c([nH]c3ccccc23)C1>>CC(C)(C)OC(=O)N1CCc2c(n(-c3ccccc3)c3ccccc23)C1 -US20130252890A1,1,CNCCCS(=O)CCCC(F)(F)C(F)(F)F.Oc1ccc2c(c1F)CCCC(c1ccc(F)cc1)=C2CCCCCCBr>>CN(CCCCCCC1=C(c2ccc(F)cc2)CCCc2c1ccc(O)c2F)CCCS(=O)CCCC(F)(F)C(F)(F)F -US20060111416A1,6,COC(=O)c1ccc2[nH]c(C(=O)N3C[C@@H]4CN(C)C[C@@H]4C3)nc2c1>>CN1C[C@H]2CN(C(=O)c3nc4cc(C(=O)O)ccc4[nH]3)C[C@H]2C1 -US20080108608A1,5,C#Cc1cccc(N)c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C#Cc1cccc(NC(=O)OC(C)(C)C)c1 -US20040242884A1,7,CC(=O)Nc1ccc(C(=O)CBr)cc1>>CC(=O)Nc1ccc(C(O)CBr)cc1 -US20140094462A1,7,C[C@@H]1CC=CCCC(=O)OC[C@@H]2CCCN2C1=O>>C[C@@H]1CCCCCC(=O)OC[C@@H]2CCCN2C1=O -US20110237612A1,7,CC(=O)c1ccc([N+](=O)[O-])s1>>CC(=O)c1ccc(N)s1 -US20090253699A1,2,CC(C)c1ccc(C(=O)Cl)cc1.COC(=O)c1cccc(C(=O)CN)c1>>COC(=O)c1cccc(C(=O)CNC(=O)c2ccc(C(C)C)cc2)c1 -US04868306,2,COc1ccc(CCN)cc1NS(C)(=O)=O.O=C(O)CCCCC(=O)NCCc1ccccc1>>COc1ccc(CCNC(=O)CCCCC(=O)NCCc2ccccc2)cc1NS(C)(=O)=O -US06369075B1,3,CCOC(=O)c1cccnc1Cl.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1cccnc1-c1ccc(C(F)(F)F)cc1 -US07160902B2,1,CI.COC(=O)CNc1ccccc1>>COC(=O)CN(C)c1ccccc1 -US07790717B2,1,CC1(C)COB(c2cccc(CBr)c2)OC1.CCNCC>>CCN(CC)Cc1cccc(B2OCC(C)(C)CO2)c1 -US04849443,1,BrCc1ccccc1.FC(F)(F)c1cc2ccccc2[nH]1>>FC(F)(F)c1cc2ccccc2n1Cc1ccccc1 -US20120207703A1,3,CCCC[Sn](CCCC)(CCCC)c1nc(C(C)C)cs1.COc1ccc(COc2cc(Cl)nc(-c3nc(C(F)(F)F)cs3)n2)cc1>>COc1ccc(COc2cc(-c3nc(C(C)C)cs3)nc(-c3nc(C(F)(F)F)cs3)n2)cc1 -US05661169,1,NC1CCCCC1.O=[N+]([O-])c1ccc(Cl)cc1Cl>>O=[N+]([O-])c1ccc(Cl)cc1NC1CCCCC1 -US06335333B1,1,Brc1ccc(-c2ccccc2)cc1.C1CCNC1>>c1ccc(-c2ccc(N3CCCC3)cc2)cc1 -US20080039437A1,2,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1C(F)F.NS(=O)(=O)Cc1ccc(F)c(F)c1>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccc(F)c(F)c3)CC2)nc1C(F)F -US08088805B2,1,CC(C)(C)OC(=O)c1ccc(F)cc1.O[C@@H]1CCNC1>>CC(C)(C)OC(=O)c1ccc(N2CC[C@@H](O)C2)cc1 -US07790727B2,2,COc1ccc(N)cc1N1CCN(C(=O)OC(C)(C)C)CC1.O=S(=O)(Cl)c1cccc(OC(F)F)c1>>COc1ccc(NS(=O)(=O)c2cccc(OC(F)F)c2)cc1N1CCN(C(=O)OC(C)(C)C)CC1 -US20100016350A1,2,CS(=O)(=O)Cl.O=C1c2sc(-c3ccc(Cl)cc3)cc2CCN1c1ccc(N2CC[C@H](O)C2)nc1>>CS(=O)(=O)O[C@H]1CCN(c2ccc(N3CCc4cc(-c5ccc(Cl)cc5)sc4C3=O)cn2)C1 -US20150238497A1,3,FC(F)(F)c1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cccc(CCCN2C(=O)c3ccccc3C2=O)c1>>O=C1c2ccccc2C(=O)N1CCCc1cccc(/C=C/c2ccccc2C(F)(F)F)c1 -US20150238497A1,3,FC(F)(F)c1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cccc(CCCN2C(=O)c3ccccc3C2=O)c1>>O=C1c2ccccc2C(=O)N1CCCc1cccc(/C=C\c2ccccc2C(F)(F)F)c1 -US20040102450A1,6,CC(C)(C)OC(=O)CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O>>O=C(O)CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O -US20150051202A1,3,CB(O)O.COc1cccc(Nc2nc3cnc(Br)cn3n2)c1>>COc1cccc(Nc2nc3cnc(C)cn3n2)c1 -US07902400B2,2,C#CCOc1ccc(C(=O)Cl)cc1F.CC1CCCCC1N>>C#CCOc1ccc(C(=O)NC2CCCCC2C)cc1F -US20080318976A1,2,COC(=O)c1ccccc1-c1ccc(CN)cc1.O=C(O)C1(O)CC1>>COC(=O)c1ccccc1-c1ccc(CNC(=O)C2(O)CC2)cc1 -US06479531B1,7,COC(=O)CNC(=O)c1cccc([N+](=O)[O-])c1>>COC(=O)CNC(=O)c1cccc(N)c1 -US05240938,9,Cc1ccc(OC(C(N)=O)c2ccccc2Cl)cc1>>Cc1ccc(OC(C#N)c2ccccc2Cl)cc1 -US05556864,6,COc1cccc(CCc2ccccc2OCC2CN(C(=O)OC(C)(C)C)CCO2)c1>>COc1cccc(CCc2ccccc2OCC2CNCCO2)c1 -US07834051B2,9,CC(=O)Nc1ccc(Br)c(Cl)c1F.N#C[Cu]>>CC(=O)Nc1ccc(C#N)c(Cl)c1F -US20140371201A1,1,COC(=O)c1cc(Br)ccc1N.COc1cc(-c2ccc(Cl)c(C)c2)c(F)cc1I>>COC(=O)c1cc(Br)ccc1Nc1cc(F)c(-c2ccc(Cl)c(C)c2)cc1OC -US08975254B2,2,C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.O=C(O)c1cn2cccnc2n1>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cn2cccnc2n1 -US20150214489A1,3,Brc1cccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c1.OB(O)c1ccc2c(c1)c1ccccc1n2-c1ccccc1>>c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)c3)n2)cc1 -US07285557B2,1,C1CCNC1.CCOC(=O)C(C)(C)Br>>CCOC(=O)C(C)(C)N1CCCC1 -US06140100,1,C=C(C)C.N[C@@H](Cc1cccc(C2CCC2)c1)C(=O)O>>CC(C)(C)OC(=O)[C@@H](N)Cc1cccc(C2CCC2)c1 -US05929120,4,CCOC(=O)c1ccc(CCC(=O)CBr)cc1.NC(N)=S>>CCOC(=O)c1ccc(CCc2csc(N)n2)cc1 -US08304557B2,2,Cc1cc(C(=O)O)n(CC(F)(F)F)n1.Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)cc1N>>Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)ccc2C)n(CC(F)(F)F)n1 -US04578459,1,CCOc1cc(Cl)nc2ccccc12.Cc1nc[nH]c1CSCCN>>CCOc1cc(NCCSCc2[nH]cnc2C)nc2ccccc12 -US07982064B2,7,O=C1C=CC(=O)c2ccccc21>>O=C1CCC(=O)c2ccccc21 -US20110003820A1,6,CC(C)NC(=O)c1ccc2n1CCN(C(=O)OC(C)(C)C)C2C>>CC(C)NC(=O)c1ccc2n1CCNC2C -US20150126485A1,1,CC1(O)CNC1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(I)c1>>CC1(O)CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc2I)C1 -US20090325964A1,2,O=C(O)c1ccc(F)c(C#Cc2ccccn2)c1.c1cnc(N2CCNCC2)nc1>>O=C(c1ccc(F)c(C#Cc2ccccn2)c1)N1CCN(c2ncccn2)CC1 -US20090227560A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn(C3CCCCC3(O)COC3CCS(=O)(=O)CC3)c2-c2ccccc2)[C@H](Cc2ccccc2)C1>>O=C(c1ncn([C@@H]2CCCC[C@@]2(O)COC2CCS(=O)(=O)CC2)c1-c1ccccc1)N1CCNC[C@H]1Cc1ccccc1 -US20090227560A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn(C3CCCCC3(O)COC3CCS(=O)(=O)CC3)c2-c2ccccc2)[C@H](Cc2ccccc2)C1>>O=C(c1ncn([C@H]2CCCC[C@]2(O)COC2CCS(=O)(=O)CC2)c1-c1ccccc1)N1CCNC[C@H]1Cc1ccccc1 -US20050154045A1,3,O=C(CC1CN2CCC1CC2)Nc1cccc(Br)c1.OCc1ccc(B(O)O)cc1>>O=C(CC1CN2CCC1CC2)Nc1cccc(-c2ccc(CO)cc2)c1 -US04820839,1,CCCCCCCCCCc1cnc(-c2ccc(C(=O)O)cc2)nc1.CCCCCCCCCc1ccc(O)c(F)c1>>CCCCCCCCCCc1cnc(-c2ccc(C(=O)Oc3ccc(CCCCCCCCC)cc3F)cc2)nc1 -US06121271,1,CCc1cc(C(=O)c2ccccc2Cl)cc(Br)c1O.CI>>CCc1cc(C(=O)c2ccccc2Cl)cc(Br)c1OC -US05587392,3,CN(C)C=O.COCOc1ccc(C(F)(F)F)cc1>>COCOc1ccc(C(F)(F)F)cc1C=O -US07524849B2,1,C[C@H](N)C(F)(F)F.Fc1cc(F)c(-c2c(Cl)nc(-c3cnccn3)nc2Cl)c(F)c1>>C[C@H](Nc1nc(-c2cnccn2)nc(Cl)c1-c1c(F)cc(F)cc1F)C(F)(F)F -US20060173056A1,2,CC(=O)Cl.CC(C)(C)OC(=O)N1C[C@@H](NCCNc2ccc(C#N)cn2)C[C@H]1C(=O)N1CCSC1>>CC(=O)N(CCNc1ccc(C#N)cn1)[C@H]1C[C@@H](C(=O)N2CCSC2)N(C(=O)OC(C)(C)C)C1 -US08492414B2,1,COc1cc(Cl)ccc1-c1nsc(CBr)n1.NC(=O)c1c(F)ccc(O)c1F>>COc1cc(Cl)ccc1-c1nsc(COc2ccc(F)c(C(N)=O)c2F)n1 -US04590315,1,COC(=O)c1cc(O)ccc1[N+](=O)[O-].N#Cc1cc(F)c(F)c(Cl)c1>>COC(=O)c1cc(Oc2c(F)cc(C#N)cc2Cl)ccc1[N+](=O)[O-] -US20150191478A1,2,CC(C)S(=O)(=O)Cl.CCOC(OCC)c1cc2cncc(N3CCNCC3)c2o1>>CCOC(OCC)c1cc2cncc(N3CCN(S(=O)(=O)C(C)C)CC3)c2o1 -US20060063760A1,7,CCOC(=O)c1ccc(NS(C)(=O)=O)cc1>>CS(=O)(=O)Nc1ccc(CO)cc1 -US20070073060A1,6,CCn1cc2c3c(cc(C(=O)OC)cc31)N(C)S(=O)(=O)CC2>>CCn1cc2c3c(cc(C(=O)O)cc31)N(C)S(=O)(=O)CC2 -US08466169B2,2,CC(=O)Cl.CON(C)C(=O)c1cc(N)c(S(F)(F)(F)(F)F)cc1C>>CON(C)C(=O)c1cc(NC(C)=O)c(S(F)(F)(F)(F)F)cc1C -US08338487B2,7,CCOC(=O)Nc1ccc2c(c1[N+](=O)[O-])CCC2Nc1ccc(F)cc1>>CCOC(=O)Nc1ccc2c(c1N)CCC2Nc1ccc(F)cc1 -US05025028,1,CCCc1c(OCCCBr)ccc(C(C)=O)c1O.OCCS>>CCCc1c(OCCCSCCO)ccc(C(C)=O)c1O -US08222260B2,1,Clc1nc(Cl)c2[nH]cnc2n1.Nc1cccc(F)c1>>Fc1cccc(Nc2nc(Cl)nc3nc[nH]c23)c1 -US07425554B2,1,CC(=O)c1ccc(C2CC(C)(C)CC(C)(C)C2)c(N2CCNCC2)c1.CCC=O>>CCCN1CCN(c2cc(C(C)=O)ccc2C2CC(C)(C)CC(C)(C)C2)CC1 -US20130030029A1,3,CC(C)(C)C1CC=C(B(O)O)CC1.CC(C)(C)OC(=O)c1ccc(C[C@@H](C(=O)O)c2ccc(Br)cc2)cc1>>CC(C)(C)OC(=O)c1ccc(C[C@@H](C(=O)O)c2ccc(C3=CCC(C(C)(C)C)CC3)cc2)cc1 -US06617339B1,7,Cc1nccn1-c1ccc([N+](=O)[O-])cc1F>>Cc1nccn1-c1ccc(N)cc1F -US06528514B1,3,CCOC(=O)C(F)(F)Br.O=CC(Cc1ccccc1)NC(=O)OCc1ccccc1>>CCOC(=O)C(F)(F)C(O)C(Cc1ccccc1)NC(=O)OCc1ccccc1 -US20120035372A1,3,C[Mg+].FC(F)(F)c1cc(Cl)nc(Cl)c1>>Cc1cc(C(F)(F)F)cc(Cl)n1 -US20100022795A1,7,CCCCCCCCCCCCCCC[C@@H](O)[C@@H](NC(C)=O)C(=O)OCC>>CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O -US20110281854A1,1,CCOC(=O)CBr.C[C@@H]1CN(c2ccc(O)c(NC(=O)C(C)(C)C)n2)[C@H](c2ccccc2)CO1>>CCOC(=O)COc1ccc(N2C[C@@H](C)OC[C@H]2c2ccccc2)nc1NC(=O)C(C)(C)C -US20110178117A1,1,CC(C)(C)CC(=O)CBr.Clc1nc2ccccc2[nH]1>>CC(C)(C)CC(=O)Cn1c(Cl)nc2ccccc21 -US20080267888A1,6,CC(C)(C)OC(=O)NC(CO)Cc1ccc(OCc2ccccc2)cc1>>NC(CO)Cc1ccc(OCc2ccccc2)cc1 -US20040122016A1,1,COC(=O)Cc1cccc(O)c1.ClCCCBr>>COC(=O)Cc1cccc(OCCCCl)c1 -US06458772B1,1,COc1ccc(CCl)cc1.O=C(O)Cc1ccccc1O>>COc1ccc(COC(=O)Cc2ccccc2O)cc1 -US20140349994A1,3,C=CCN(c1c(C(=O)C=C)cnn1Cc1ccc(OC)cc1)[C@@H](C)COC>>COC[C@H](C)N1CC=CC(=O)c2cnn(Cc3ccc(OC)cc3)c21 -US20100120841A1,7,O=C1Cc2c(Br)ccc3cccc1c23>>OC1Cc2c(Br)ccc3cccc1c23 -US05304563,1,CCOC(=O)Cc1ccc(O)c(SC(F)(F)F)c1.ClCc1ccc2ccccc2n1>>CCOC(=O)Cc1ccc(OCc2ccc3ccccc3n2)c(SC(F)(F)F)c1 -US05952342,2,CC(C)N=C=O.CCN(CC)CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(N)nc2n1>>CCN(CC)CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)C)nc2n1 -US20090149450A1,2,CC(C)(C)OC(=O)N1CCn2c(C(=O)c3ccccc3)nc(C(=O)O)c2C1.CNC(=O)[C@@H](N)C(C)(C)C>>CNC(=O)[C@@H](NC(=O)c1nc(C(=O)c2ccccc2)n2c1CN(C(=O)OC(C)(C)C)CC2)C(C)(C)C -US20100048849A1,1,CCCCCC1CCC(C(=O)O)CC1.O=C(/C=C/c1ccc(O)cc1)OCCCCCCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CCCCCC1CCC(C(=O)Oc2ccc(/C=C/C(=O)OCCCCCCOC(=O)c3cc([N+](=O)[O-])cc([N+](=O)[O-])c3)cc2)CC1 -US05272145,4,COC(=O)C(C)(C)CC(=O)CSC(C)(C)C.COc1cccc(NN)c1>>COC(=O)C(C)(C)Cc1[nH]c2cc(OC)ccc2c1SC(C)(C)C -US20080300136A1,6,CCOC(=O)c1csc(NC(=O)c2ccccc2Cl)n1>>O=C(O)c1csc(NC(=O)c2ccccc2Cl)n1 -US20130204037A1,1,CCO.O=C(O)c1ccc(O)cc1>>CCOc1ccc(C(=O)O)cc1 -US20090099184A1,1,O=C(NCc1ccc(Cl)cc1Cl)c1ccc(F)nc1.Oc1ccc(F)cc1>>O=C(NCc1ccc(Cl)cc1Cl)c1ccc(Oc2ccc(F)cc2)nc1 -US05861109,3,CCCCCCCCOc1ccc(B(O)O)cc1F.Fc1cc(Br)ccc1I>>CCCCCCCCOc1ccc(-c2ccc(Br)cc2F)cc1F -US06245761B1,1,CN(C)CCCCO.Fc1ccc(Br)cc1CBr>>CN(C)CCCCOCc1cc(Br)ccc1F -US07935721B2,1,CC1(C)COc2cc3c(cc21)C1(CO3)C(=O)Nc2ccccc21.FC(F)(F)c1ccc(CBr)o1>>CC1(C)COc2cc3c(cc21)C1(CO3)C(=O)N(Cc2ccc(C(F)(F)F)o2)c2ccccc21 -US20150166549A1,3,CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(I)c2c(N)ncnc21.Nc1ncc(B(O)O)cn1>>CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(-c2cnc(N)nc2)c2c(N)ncnc21 -US20130059849A1,2,CC(C)n1ncc2c(C(=O)O)cc(-c3ccc(-c4cn[nH]c4)cc3)nc21.Cc1cc(C)c(CN)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(-c4cn[nH]c4)cc3)nc3c2cnn3C(C)C)c(=O)[nH]1 -US20020058665A1,2,COC(=O)[C@@H](N)CCSC.Cc1cn(CC(Oc2ccc(CCc3ccc(F)cc3)c(C(=O)O)c2)c2nccs2)cn1>>COC(=O)[C@H](CCSC)NC(=O)c1cc(OC(Cn2cnc(C)c2)c2nccs2)ccc1CCc1ccc(F)cc1 -US06211215B1,1,Cc1ccc(-c2nc(CCl)co2)o1.Oc1ccc(CCCCn2ccnc2)cc1>>Cc1ccc(-c2nc(COc3ccc(CCCCn4ccnc4)cc3)co2)o1 -US20080194586A1,9,CCCc1cc(Oc2ccc(Cl)cc2)ccc1C(=O)c1cc(OC)c(Cl)cc1F.NO>>CCCc1cc(Oc2ccc(Cl)cc2)ccc1/C(=N/O)c1cc(OC)c(Cl)cc1F -US06358971B1,2,CNOC.Nc1nc2ccc(C(=O)O)cn2c1-c1ccccc1>>CON(C)C(=O)c1ccc2nc(N)c(-c3ccccc3)n2c1 -US20050277670A1,5,CC(=O)c1ccc(N)cc1.OCCO>>CC1(c2ccc(N)cc2)OCCO1 -US08232391B2,1,COc1ccc2nccc(-n3cc4c(n3)CCC(N)C4)c2n1.O=CCCc1ccccc1>>COc1ccc2nccc(-n3cc4c(n3)CCC(NCCCc3ccccc3)C4)c2n1 -US20080153850A1,6,COC(=O)Cc1ccccc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>O=C(O)Cc1ccccc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 -US07462713B2,2,Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O.O=C(O)c1cccc(F)c1F>>O=C(Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)c1cccc(F)c1F -US20100076000A1,1,CCOC(=O)N=S(=O)(CC)c1ccc(N)cc1.C[C@@H](O)[C@@H](C)Oc1nc(Cl)ncc1Br>>CCOC(=O)N=S(=O)(CC)c1ccc(Nc2ncc(Br)c(O[C@H](C)[C@@H](C)O)n2)cc1 -US20150099737A1,1,CC(C)(C)OC(=O)N1C2CCC1CC1(CC(=O)N(c3ccc(N)nc3)C1)C2.CN(C)C(=O)c1cc2cnc(Cl)nc2n1C1CCCC1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CC5(CC4=O)CC4CCC(C5)N4C(=O)OC(C)(C)C)cn3)nc2n1C1CCCC1 -US08481042B2,1,C=O.CSSC(C)(C)CNCCOc1cc(CO)nc(CO)c1>>CSSC(C)(C)CN(C)CCOc1cc(CO)nc(CO)c1 -US20120035164A1,8,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CO)c4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(C=O)c4)cc23)CC1 -US20140288045A1,6,CCOC(=O)Cc1c[nH]c2cc(Cl)c(Cl)cc12>>O=C(O)Cc1c[nH]c2cc(Cl)c(Cl)cc12 -US20110021573A1,7,C[C@H](NC(=O)OCc1ccccc1)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@H](NC(=O)OCc1ccccc1)C(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US03933829,2,CN(C)C1CCNCC1.O=S(=O)(Cl)c1ccc(Nc2ccnc3cc(Cl)ccc23)cc1>>CN(C)C1CCN(S(=O)(=O)c2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)CC1 -US08486950B2,2,N#Cc1cc(F)c(C(=O)Cl)c(Cl)c1.Nc1ccnc(Br)c1>>N#Cc1cc(F)c(C(=O)Nc2ccnc(Br)c2)c(Cl)c1 -US20130045975A1,1,CNCCCN(C)C.COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)[nH]c2c1OCCCCCCCl>>COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)[nH]c2c1OCCCCCCN(C)CCCN(C)C -US06562823B1,7,CCOC(=O)/C=C/c1ccc(C#N)c(F)c1>>CCOC(=O)CCc1ccc(C#N)c(F)c1 -US05256824,7,O=C1C=CC(C2CC2)(C2CC2)C1>>OC1C=CC(C2CC2)(C2CC2)C1 -US08802886B2,3,CCOC(=O)C(F)(F)Br.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(C(F)(F)C(=O)OCC)cc1 -US05292732,4,CC(=O)NCCN.O=CCC1CCc2cc(Cl)ccc2C1=O>>CC(=O)NCCn1ccc2c1-c1ccc(Cl)cc1CC2 -US20100048537A1,1,CCOC(=O)CCN.O=Cc1cccs1>>CCOC(=O)CCNCc1cccs1 -US20140142085A1,1,Cc1nc(C(F)(F)F)n[nH]1.NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)CCl)ccc1F>>Cc1nc(C(F)(F)F)nn1CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncccc1-c1ccc(F)c(C(N)=O)c1 -US20100305092A1,1,CC(C)N.O=Cc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1>>CC(C)NCc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1 -US20110288069A1,7,CC(C)(C)OC(=O)N1CC[C@H]1C(=O)N1CCC2CN(Cc3ccc(F)cc3)CCN2c2ncccc21>>CC(C)(C)OC(=O)N1CC[C@H]1CN1CCC2CN(Cc3ccc(F)cc3)CCN2c2ncccc21 -US20100317657A1,1,CC(C)Oc1cccnc1Cl.CO>>COc1ncccc1OC(C)C -US20130225584A1,6,COC(=O)c1cc(C(F)(F)F)c(CN2CCCCC2)cc1OCc1ccccc1>>O=C(O)c1cc(C(F)(F)F)c(CN2CCCCC2)cc1OCc1ccccc1 -US20080076774A1,1,CC(C)CCNc1c(F)c(NCCN2CCCC2)nc(N2CCNCC2)c1F.Clc1ncnc2[nH]nc(Br)c12>>CC(C)CCNc1c(F)c(NCCN2CCCC2)nc(N2CCN(c3ncnc4[nH]nc(Br)c34)CC2)c1F -US20080234384A1,1,O=C(O)c1cc(C(F)(F)F)ccc1Cl.O=C(O)c1cc(F)ccc1S>>O=C(O)c1cc(F)ccc1Sc1ccc(C(F)(F)F)cc1C(=O)O -US06352999B1,1,O=[N+]([O-])c1ccc(CCl)cc1.c1ccc2c3c(oc2c1)CCNC3>>O=[N+]([O-])c1ccc(CN2CCc3oc4ccccc4c3C2)cc1 -US05872138,1,CCOC(=O)c1ccc(O)cc1.OCc1ccc2c(c1)OCO2>>CCOC(=O)c1ccc(OCc2ccc3c(c2)OCO3)cc1 -US20090192213A1,6,CN(Cc1ccccc1Sc1coc2ccccc12)C(=O)OC(C)(C)C>>CNCc1ccccc1Sc1coc2ccccc12 -US20100227859A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)[C@H](NS(=O)(=O)c1ccc2sc3cc(I)ccc3c2c1)C(C)C>>COC(=O)[C@H](NS(=O)(=O)c1ccc2sc3cc(B4OC(C)(C)C(C)(C)O4)ccc3c2c1)C(C)C -US06069156,2,COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(N)c1.O=C(Cl)OCc1ccccc1>>COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(NC(=O)OCc2ccccc2)c1 -US07531553B2,1,CNC(=O)c1cccc(O)c1.Nc1ccc(Cl)cc1[N+](=O)[O-]>>CNC(=O)c1cccc(Oc2ccc(N)c([N+](=O)[O-])c2)c1 -US04000151,9,Clc1cc(-c2ccccc2Cl)c2ccccc2n1.NN>>NNc1cc(-c2ccccc2Cl)c2ccccc2n1 -US20030039768A1,1,CCCCOc1ccc(/C=C/C(=O)O)cc1OC.OCCCCCCCl>>CCCCOc1ccc(/C=C/C(=O)OCCCCCCO)cc1OC -US20100022491A1,2,O=C(Cl)CCN(CCc1ccccc1)C(=O)OCc1ccccc1.O=C(OCc1ccccc1)N(CCNC1CCCCCC1)CCc1ccc(O)c2[nH]c(=O)sc12>>O=C(OCc1ccccc1)N(CCC(=O)N(CCN(CCc1ccc(O)c2[nH]c(=O)sc12)C(=O)OCc1ccccc1)C1CCCCCC1)CCc1ccccc1 -US07241761B2,2,CC(C)COc1ccc(S(C)(=O)=O)cc1C(=O)O.c1ccc2nc(N3CCNCC3)cnc2c1>>CC(C)COc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2cnc3ccccc3n2)CC1 -US08513248B2,3,FC(F)(F)c1nc2cnccn2c1Br.OB(O)c1ccc(F)cc1>>Fc1ccc(-c2c(C(F)(F)F)nc3cnccn23)cc1 -US20110082164A1,3,Brc1cncc(Br)n1.OB(O)c1ccccc1>>Brc1cncc(-c2ccccc2)n1 -US20080300231A1,9,CC(C)(C)OC(=O)NCCCC[C@@H](CN=[N+]=[N-])NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCC[C@@H](CN)NC(=O)OC(C)(C)C -US07541365B2,1,CC(C)(O)c1ccc2c(c1)C(=CCCBr)c1cccnc1CO2.O=[N+]([O-])c1cc(C2(O)CCNCC2)ccc1Cl>>CC(C)(O)c1ccc2c(c1)C(=CCCN1CCC(O)(c3ccc(Cl)c([N+](=O)[O-])c3)CC1)c1cccnc1CO2 -US20140323499A1,9,COC(=O)c1cc(N)cc(-c2ccc(C)cn2)c1.ICI>>COC(=O)c1cc(I)cc(-c2ccc(C)cn2)c1 -US20090082434A1,9,CC1(CN=[N+]=[N-])Cc2cc(Cl)cc(-c3cccs3)c2O1>>CC1(CN)Cc2cc(Cl)cc(-c3cccs3)c2O1 -US20110166169A1,1,FC(F)(F)c1ccc(-c2cccc3[nH]c4ccccc4c23)cn1.N#Cc1ccc(Br)cc1F>>N#Cc1ccc(-n2c3ccccc3c3c(-c4ccc(C(F)(F)F)nc4)cccc32)cc1F -US07888352B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.O=C(CO)N1CCN(Cc2cc3c(N4CCOCC4)nc(Cl)nc3s2)CC1>>Nc1ccc(-c2nc(N3CCOCC3)c3cc(CN4CCN(C(=O)CO)CC4)sc3n2)cn1 -US20100227834A1,1,CS(=O)(=O)OC[C@H]1O[C@@H](n2cc(/C=C/Br)c(=O)[nH]c2=O)C[C@@H]1Cl.[N-]=[N+]=[N-]>>[N-]=[N+]=NC[C@H]1O[C@@H](n2cc(/C=C/Br)c(=O)[nH]c2=O)C[C@@H]1Cl -US05561150,9,CCOC1=C2C=c3c(cnn3CC(C)N=[N+]=[N-])=C2CC=C1>>CCOC1=C2C=c3c(cnn3CC(C)N)=C2CC=C1 -US06881733B1,9,CC1(C)CN(Cc2ccccc2)CCC1(O)c1c(F)cc(F)c2ccoc12>>CC1(C)CN(Cc2ccccc2)CCC1c1c(F)cc(F)c2ccoc12 -US08426447B2,7,COC(C)(C)C#Cc1ccc2c(c1)[C@]1(COC(N)=N1)c1cc(-c3cncnc3)ccc1O2>>COC(C)(C)CCc1ccc2c(c1)[C@]1(COC(N)=N1)c1cc(-c3cncnc3)ccc1O2 -US20140275080A1,3,C=CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1.COC(C)(C)C(=O)NC(=O)Nc1ccc(Oc2ccnc(Cl)c2)cn1>>C=CCn1cc(-c2cc(Oc3ccc(NC(=O)NC(=O)C(C)(C)OC)nc3)ccn2)cn1 -US06756378B2,7,CC(C)(C)OC(=O)N1[C@H](COCc2ccccc2)CC[C@H]1COC(=O)c1ccccc1>>CC(C)(C)OC(=O)N1[C@H](COCc2ccccc2)CC[C@H]1CO -US06455521B1,1,O=C(Nc1ccc(F)cc1O)c1c(Br)sc2c1CCCC2>>O=C1Nc2ccc(F)cc2Oc2sc3c(c21)CCCC3 -US20040132727A1,6,COc1cc2nccc(Oc3ccc(NC(=O)NC4CCN(Cc5ccccc5)CC4)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)NC4CCNCC4)cc3)c2cc1OC -US09079866B2,1,Nc1ncc(-c2ccc(-c3ccc(C(F)(F)F)cc3O)cc2F)cn1.Nc1nccc(Cl)n1>>Nc1ncc(-c2ccc(-c3ccc(C(F)(F)F)cc3Oc3ccnc(N)n3)cc2F)cn1 -US20100173888A1,2,CCn1cnc2c1CCC(N)C2.O=C(O)c1ccc(-c2cccc(F)c2)nc1>>CCn1cnc2c1CCC(NC(=O)c1ccc(-c3cccc(F)c3)nc1)C2 -US20080269210A1,3,CNC(=O)c1cccc(B(O)O)c1.Clc1nc(N2CCOCC2)c2sc(I)cc2n1>>CNC(=O)c1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1 -US20110269712A1,6,COC(=O)c1ccn(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>COC(=O)c1ccn(C2CCNCC2)n1 -US05760054,2,O=C1c2cccnc2S(=O)(=O)N1CCCCO.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>O=C1c2cccnc2S(=O)(=O)N1CCCCOS(=O)(=O)c1ccc([N+](=O)[O-])cc1 -US20060100436A1,6,CCOC(=O)c1cn(CC)c2c(OC)c(F)ccc2c1=O>>CCn1cc(C(=O)O)c(=O)c2ccc(F)c(OC)c21 -US04618713,9,O=C(CCl)Nc1c(CCl)cccc1C(F)(F)F>>Cc1cccc(C(F)(F)F)c1NC(=O)CCl -US20150065464A1,1,N.O=C1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)c(Cl)n3)c2)CC1>>NC1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)c(Cl)n3)c2)CC1 -US08785638B2,6,CCCC(C(=O)OC)c1c(C)nc2sc3ccccc3c2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2sc3ccccc3c2c1-c1ccc(C)cc1 -US20090221663A1,2,CCCSc1c(C(=O)O)cnn1-c1ccc(CC(=O)OC)cc1.NC1C2CC3CC(C2)CC1C3>>CCCSc1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccc(CC(=O)OC)cc1 -US07834197B2,1,CN1CCCC1.COCBr>>COC[N+]1(C)CCCC1 -US07662825B2,1,Cc1cccnc1CO.Cc1cnc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(Br)n1>>Cc1cnc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(OCc2ncccc2C)n1 -US20150158879A1,7,CC(O)(CC(=O)Nc1ccc(Cl)cc1N)C(F)(F)F>>CC(O)(CCNc1ccc(Cl)cc1N)C(F)(F)F -US20040220191A1,3,CC(C)(C)OC(=O)NN1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Clc1ccc(Br)nc1>>CC(C)(C)OC(=O)NN1CC=C(c2ccc(Cl)cn2)CC1 -US20060100226A1,6,COc1cccc(-c2nc(SCc3ccc(NC(=O)OC(C)(C)C)cc3)[nH]c(=O)c2C#N)c1>>COc1cccc(-c2nc(SCc3ccc(N)cc3)[nH]c(=O)c2C#N)c1 -US04863951,9,NO.O=C1CCCc2cc3c(cc21)OCC3>>ON=C1CCCc2cc3c(cc21)OCC3 -US06083908,6,CN(NC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C>>CN[C@H](Cc1ccccc1)C(=O)NN(C)C(=O)OC(C)(C)C -US20140038999A1,7,C=Cc1cc2c3ccnc(C)c3c(=O)n(C)c2cc1OC[C@H](CC(C)C)NC(=O)OC(C)(C)C>>CCc1cc2c3ccnc(C)c3c(=O)n(C)c2cc1OC[C@H](CC(C)C)NC(=O)OC(C)(C)C -US20080318923A1,1,COc1ccccc1C1(Cl)C(=O)Nc2ccc(Cl)cc21.C[C@H](NCc1ccccc1)C(=O)N(C)C>>COc1ccccc1C1(N(Cc2ccccc2)[C@@H](C)C(=O)N(C)C)C(=O)Nc2ccc(Cl)cc21 -US06610727B2,1,O=C1NC(=O)c2c1c1c3cc(F)c(F)cc3[nH]c1c1c2c2cc(F)c(F)cc2n1[C@@H]1O[C@H](CO)C[C@H](O)[C@H]1OCc1ccccc1>>O=C1NC(=O)c2c1c1c3cc(F)c(F)cc3[nH]c1c1c2c2cc(F)c(F)cc2n1[C@@H]1O[C@@H]2CO[C@@H](C2)[C@H]1OCc1ccccc1 -US06521620B1,1,CN.Fc1cc2ncnc(Nc3cccc(Br)c3)c2cn1>>CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1 -US06087381,7,Cc1n[nH]c(C=Cc2ccccc2)c1-c1ccncc1>>Cc1n[nH]c(CCc2ccccc2)c1-c1ccncc1 -US20100093825A1,1,Clc1ccc(CBr)cc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)OCc3ccc(Cl)cc3)(CC1)CC2 -US20070172421A1,6,CN1C(=O)C(CN2CCCCC2)CC1c1ncc(-c2ccc3c(c2)OCO3)n1Cc1ccccc1>>CN1C(=O)[C@@H](CN2CCCCC2)C[C@H]1c1ncc(-c2ccc3c(c2)OCO3)[nH]1 -US20090093454A1,1,CN1CCCC(CCl)C1.c1cnc2c(c1)CC[C@H]1CCCN(Cc3nc4ccccc4[nH]3)[C@H]21>>CN1CCCC(Cn2c(CN3CCC[C@@H]4CCc5cccnc5[C@H]43)nc3ccccc32)C1 -US07872128B2,1,CCc1ccc(N)cc1.COC(=O)c1c(Cl)ccc(C(Cl)=NO)c1F>>CCc1ccc(NC(=NO)c2ccc(Cl)c(C(=O)OC)c2F)cc1 -US20040082611A1,2,CO.Nc1ccc(-c2ccc(C(=O)O)cc2)cn1>>COC(=O)c1ccc(-c2ccc(N)nc2)cc1 -US07951826B2,1,FC(F)(F)CCCBr.O=C(c1ccc(O)cc1)N1CCC[C@H]1CN1CCCC1>>O=C(c1ccc(OCCCC(F)(F)F)cc1)N1CCC[C@H]1CN1CCCC1 -US08263606B2,1,BrCC1CCCCO1.O=C1Nc2ccccc2C12COc1cc3c(cc12)CCO3>>O=C1N(CC2CCCCO2)c2ccccc2C12COc1cc3c(cc12)CCO3 -US20040176374A1,6,CCOC(=O)C(=O)Nc1cccc(-c2nc(-c3ccc(S(=O)(=O)Nc4cccc(NC(=O)C5(C)CC5)c4)cc3)no2)n1>>CC1(C(=O)Nc2cccc(NS(=O)(=O)c3ccc(-c4noc(-c5cccc(NC(=O)C(=O)O)n5)n4)cc3)c2)CC1 -US09067898B1,7,C=C(C)c1nsc(-c2ccc(C)cc2F)c1C#N>>Cc1ccc(-c2snc(C(C)C)c2C#N)c(F)c1 -US20150152096A1,6,CC(C)(C)OC(=O)N1CCOCC1C1N=NN=N1>>C1COCC(C2N=NN=N2)N1 -US07176310B1,2,Nc1cccnc1.O=C(O)COc1ncc(C(=O)Nc2ccc(F)cc2)cn1>>O=C(COc1ncc(C(=O)Nc2ccc(F)cc2)cn1)Nc1cccnc1 -US09139534B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCC[C@H](O)C1>>CC(C)(C)OC(=O)N[C@@H]1CCC[C@H](O)C1 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.Cc1ccc(OCCCCCl)cc1C>>Cc1ccc(OCCCCN2CCC(c3cccc(NC(=O)C(C)C)c3)CC2)cc1C -US06084130,6,CC(C)(C)OC(=O)NC1Cc2cnc(CNC(=O)OCc3ccccc3)cc2C1>>NC1Cc2cnc(CNC(=O)OCc3ccccc3)cc2C1 -US05225442,2,COc1ccc2cccc(CCN)c2c1.O=CO>>COc1ccc2cccc(CCNC=O)c2c1 -US04576952,1,Cc1cc(Cl)c2[nH]ncc2n1.Nc1ccc(O)cc1>>Cc1cc(Nc2ccc(O)cc2)c2[nH]ncc2n1 -US20110020278A1,1,CC1CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)[C@@H]2C[C@H](O)C2)CC1.Fc1cccnc1>>C[C@H]1CC[C@H](C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)[C@@H]2C[C@H](Oc3cccnc3)C2)CC1 -US07528158B2,7,O=c1[nH]n(Cc2ccc(Cl)cc2)c2ccc([N+](=O)[O-])cc12>>Nc1ccc2c(c1)c(=O)[nH]n2Cc1ccc(Cl)cc1 -US07166587B2,6,CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CN(C(=O)c2ccccc2)c2ccccc21>>CN1C(=O)[C@@H](N)CN(C(=O)c2ccccc2)c2ccccc21 -US20080318947A1,3,C#CC(C)(C)O.CCn1c(-c2nonc2N)nc2c(Cl)nc(CN3C(=O)c4ccccc4C3=O)cc21>>CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(CN3C(=O)c4ccccc4C3=O)cc21 -US07579368B2,7,CCOC(=O)c1ccc([N+](=O)[O-])cc1OCC>>CCOC(=O)c1ccc(N)cc1OCC -US07935835B2,6,CCOC(=O)C1=CC2(CCC1S(=O)(=O)Nc1ccc(F)cc1Cl)OCCO2>>O=C(O)C1=CC2(CCC1S(=O)(=O)Nc1ccc(F)cc1Cl)OCCO2 -US06951855B2,6,COc1ccc(Nc2ccc3c(c2)OCC(=O)N3)cc1>>O=C1COc2cc(Nc3ccc(O)cc3)ccc2N1 -US20140336208A1,1,CCC1CC(=O)c2ccccc21.CN1C(=O)C(C)(C)[C@@](C)(c2cc(N)ccc2F)N=C1N>>CCC1CC(Nc2ccc(F)c([C@@]3(C)N=C(N)N(C)C(=O)C3(C)C)c2)c2ccccc21 -US08188073B2,2,CC(=O)Cl.CC1(C)Oc2cc(NS(C)(=O)=O)ccc2N(c2ccc(F)c(N)c2)C1=O>>CC(=O)Nc1cc(N2C(=O)C(C)(C)Oc3cc(NS(C)(=O)=O)ccc32)ccc1F -US20130237535A1,2,CC(=O)Cl.Nc1cnc2cc(-c3ccc(S(=O)(=O)N4CCC5(CC4)CN(C4CC4)C(=O)CO5)cc3)ccc2c1>>CC(=O)Nc1cnc2cc(-c3ccc(S(=O)(=O)N4CCC5(CC4)CN(C4CC4)C(=O)CO5)cc3)ccc2c1 -US20150183801A1,1,O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1.OC[C@H]1CCNC1>>O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@H](CO)C2)c(Br)c1 -US08481731B2,1,COc1c(Cl)ncnc1OC1CCN(C(=O)OC(C)C)CC1.CS(=O)(=O)c1ccc2c(c1)CCN2>>COc1c(OC2CCN(C(=O)OC(C)C)CC2)ncnc1N1CCc2cc(S(C)(=O)=O)ccc21 -US20140038976A1,3,CB1OB(C)OB(C)O1.O=C1c2cccnc2C2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3Br)CCN12>>Cc1cc(C(F)(F)F)ccc1S(=O)(=O)N1CCN2C(=O)c3cccnc3C2C1 -US06432950B1,1,Cc1csc2nc(-c3ccncc3)nc(Cl)c12.NCCc1ccc2c(c1)OCCO2>>Cc1csc2nc(-c3ccncc3)nc(NCCc3ccc4c(c3)OCCO4)c12 -US05716944,7,O=C(O)CCC(=O)c1ccc(C2CCCCC2)cc1>>O=C(O)CCCc1ccc(C2CCCCC2)cc1 -US20150284370A1,3,CCN(c1cc(Br)cc(C(=O)OC)c1C)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1.OB(O)c1ccc(O)nc1>>CCN(c1cc(-c2ccc(O)nc2)cc(C(=O)OC)c1C)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1 -US08916589B2,1,N.O=Cc1ccc(Oc2ccccc2Cl)cc1F>>NCc1ccc(Oc2ccccc2Cl)cc1F -US20100121048A1,3,CCOP(=O)(Cc1ccccc1)OCC.Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2C=O)c(-c2ccccc2)n1-c1ccccc1>>Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2/C=C/c2ccccc2)c(-c2ccccc2)n1-c1ccccc1 -US20070078125A1,1,COc1cc([N+](=O)[O-])ccc1Cl.O[C@@H]1CCNC1>>COc1cc([N+](=O)[O-])ccc1N1CC[C@@H](O)C1 -US08614239B2,7,COc1c([N+](=O)[O-])c(F)c(F)c2c1[nH]c(=O)n2-c1ccc(I)cc1F>>COc1c(N)c(F)c(F)c2c1[nH]c(=O)n2-c1ccc(I)cc1F -US04177193,2,COC(=O)C1=C(O)c2cscc2S(=O)(=O)N1C.Nc1nccs1>>CN1C(C(=O)Nc2nccs2)=C(O)c2cscc2S1(=O)=O -US08114872B2,3,Brc1cccc2ccsc12.CC1(C)OB(c2ccnc(Cl)c2)OC1(C)C>>Clc1cc(-c2cccc3ccsc23)ccn1 -US20100227845A1,1,CCCCO.O=C(O)c1cccnc1Cl>>CCCCOc1ncccc1C(=O)O -US08063061B2,2,CC(=O)O.NNc1ccc(I)cc1>>CC(=O)NNc1ccc(I)cc1 -US08314126B2,7,CCN1CC=C(c2cccc(S(=O)(=O)N(C)C)c2F)CC1>>CCN1CCC(c2cccc(S(=O)(=O)N(C)C)c2F)CC1 -US20110257151A1,1,CC1(C)COC(=O)N1.CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(Br)c1>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(N2C(=O)OCC2(C)C)c1 -US20060154973A1,7,CCOC(=O)c1csc(NC(=O)OC(C)(C)C)n1>>CC(C)(C)OC(=O)Nc1nc(CO)cs1 -US08163752B2,3,C=O.CNC.O=[N+]([O-])c1cccc2cc[nH]c12>>CN(C)Cc1c[nH]c2c([N+](=O)[O-])cccc12 -US04317817,8,C[C@@H](CO)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C(=[N+]=[N-])C(=O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@@H](C=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C(=[N+]=[N-])C(=O)CC[C@]4(C)[C@H]3CC[C@]12C -US20090176774A1,8,COc1cc2nccc(Sc3ccccc3)c2cc1OC.O=C(OO)c1cccc(Cl)c1>>COc1cc2nccc(S(=O)c3ccccc3)c2cc1OC -US06043366,1,ClCCN1CCOCC1.O=C1NCN(c2ccccc2)C12CCN(C1CCCCCCCCC1)CC2>>O=C1N(CCN2CCOCC2)CN(c2ccccc2)C12CCN(C1CCCCCCCCC1)CC2 -US04970213,1,CN1CCNCC1.O=C(O)c1cn(C2CC2)c2nc3cc(F)c(F)cc3cc2c1=O>>CN1CCN(c2cc3nc4c(cc3cc2F)c(=O)c(C(=O)O)cn4C2CC2)CC1 -US07235555B2,1,CN1CCNCC1.COC(=O)Cc1cc(Br)cc(C)c1Cl>>COC(=O)Cc1cc(N2CCN(C)CC2)cc(C)c1Cl -US06153605,9,BrC(Br)(Br)Br.C[C@H](C=O)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C>>C[C@H](C=C(Br)Br)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C -US08106215B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(C)C[C@@H]3[C@H]2CN)c1.O=C(O)c1cccc2occc12>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(C)C[C@@H]3[C@H]2CNC(=O)c2cccc3occc23)c1 -US20110269781A1,1,BrCC1CCOCC1.COc1nc2c(N)nc(OCCC(C)C)nc2[nH]1>>COc1nc2c(N)nc(OCCC(C)C)nc2n1CC1CCOCC1 -US07718999B2,1,CCCCBr.OCc1ccsc1>>CCCCOCc1ccsc1 -US20140243286A1,6,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCNC(=O)OC(C)(C)C)c1nnc(C)n1-2>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCN)c1nnc(C)n1-2 -US20140206662A1,9,N.OCc1c(-c2ccc(F)cc2)nc2cnc(Br)cn12>>Nc1cn2c(CO)c(-c3ccc(F)cc3)nc2cn1 -US20150266881A1,3,COC(=O)c1cccc(/C=C/C(=O)OC(C)(C)C)c1.C[S+](C)(C)=O>>COC(=O)c1cccc([C@@H]2C[C@H]2C(=O)OC(C)(C)C)c1 -US04931083,1,CCOC(=O)C(C)Br.Oc1ncn(-c2ccc(Cl)c(Cl)c2)n1>>CCOC(=O)C(C)Oc1ncn(-c2ccc(Cl)c(Cl)c2)n1 -US20120295875A1,6,COC(COc1ccc2c(c1)B(O)OC2)OC>>O=CCOc1ccc2c(c1)B(O)OC2 -US20150038438A1,6,COC(=O)c1cc2c(n(Cc3ccc(OC)cc3OC)c1=O)-c1ccc(Cl)cc1OCC2>>COc1ccc(Cn2c3c(cc(C(=O)O)c2=O)CCOc2cc(Cl)ccc2-3)c(OC)c1 -US04916149,2,CC(=O)N(N)c1ccc(C(F)(F)F)cc1N.O=C(Cl)c1ccccc1>>CC(=O)N(N)c1ccc(C(F)(F)F)cc1NC(=O)c1ccccc1 -US05834463,7,O=C1C2CCCC2=Nc2ccccc2N1Cc1ccc(Cl)cc1Cl>>O=C1C2CCCC2Nc2ccccc2N1Cc1ccc(Cl)cc1Cl -US08003785B2,2,COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C.NCC(O)CN1CCNCC1>>COc1cc(C(=O)NCC(O)CN2CCNCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US09133148B2,3,CC(C)(C)OC(=O)N1CCN(Cc2ccc(Br)cc2Oc2ccccc2)CC1.Cc1cccc(B(O)O)c1>>Cc1cccc(-c2ccc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(Oc3ccccc3)c2)c1 -US20120065202A1,3,CC1(C)OB(c2ccc(NC(=O)NC3CC3)cc2F)OC1(C)C.COC(=O)N1Cc2nc(Cl)nc(N3CCOC[C@@H]3C)c2C1>>COC(=O)N1Cc2nc(-c3ccc(NC(=O)NC4CC4)cc3F)nc(N3CCOC[C@@H]3C)c2C1 -US03987091,2,CC(=O)OC(C)=O.CCCCCC(CCCN)OC1CCCCO1>>CCCCCC(CCCNC(C)=O)OC1CCCCO1 -US04861798,7,O=C(O)CCCCCC(=O)CCc1ccc(Cl)cc1>>O=C(O)CCCCCCCCc1ccc(Cl)cc1 -US05726185,6,CCOC(=O)COc1ccc(C(=O)[C@H](C)NC(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CCOC(=O)COc1ccc(C(=O)[C@H](C)NC(=O)CCC2CCNCC2)cc1 -US20090093476A1,1,COC(=O)c1cc(-c2ccccc2)cn1-c1cc(Cl)ccc1[N+](=O)[O-].NCCCN1CCOCC1>>COC(=O)c1cc(-c2ccccc2)cn1-c1cc(NCCCN2CCOCC2)ccc1[N+](=O)[O-] -US05972972,2,COc1ccnc(CO)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccnc(COS(=O)(=O)c2ccc(C)cc2)c1 -US08404708B2,2,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CNc1cnc(Cl)cc1-c1cccnc1C>>Cc1ncccc1-c1cc(Cl)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20120289522A1,1,CI.Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1CCC(=O)NC(C)(C)c1ccccc1>>Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1CCC(=O)N(C)C(C)(C)c1ccccc1 -US20120190677A1,2,CC1(C)CC(c2cc(N3CCOCC3)ccc2Cl)Nc2ccc(C(=O)O)cc21.CS(N)(=O)=O>>CC1(C)CC(c2cc(N3CCOCC3)ccc2Cl)Nc2ccc(C(=O)NS(C)(=O)=O)cc21 -US20080027050A1,6,CCOC(=O)c1ccc(COCc2csc3nc(C(=O)NCc4cccc(OCC)c4)[nH]c(=O)c23)cc1>>CCOc1cccc(CNC(=O)c2nc3scc(COCc4ccc(C(=O)O)cc4)c3c(=O)[nH]2)c1 -US07244763B2,9,COC(=O)C1(c2ccc(S(=O)(=O)Cl)cc2)CC1>>COC(=O)C1(c2ccc(S)cc2)CC1 -US06384041B1,1,CCc1cc2c(Cl)nc(SC)nc2n1Cc1ccccc1-c1ccccc1.COC(=O)CO>>CCc1cc2c(OCC(=O)OC)nc(SC)nc2n1Cc1ccccc1-c1ccccc1 -US08338605B2,2,CNC.O=C(Cl)c1cccc(Oc2ccc(Cl)cc2[N+](=O)[O-])c1>>CN(C)C(=O)c1cccc(Oc2ccc(Cl)cc2[N+](=O)[O-])c1 -US20140163009A1,3,CCOC(=O)/C=C/c1cc(Cl)nc(Cl)c1.OB(O)C1CC1>>CCOC(=O)/C=C/c1cc(Cl)nc(C2CC2)c1 -US20040033995A1,1,BrCC=Cc1ccccc1.CCOC(=O)C=CC(Cc1c[nH]cn1)NC(=O)CCCCCCc1ccccc1>>CCOC(=O)C=CC(Cc1cn(CC=Cc2ccccc2)cn1)NC(=O)CCCCCCc1ccccc1 -US06310061B2,1,CNc1ccc(C#N)cc1Cl.COCO[C@H]1CCN(C[C@@H](O)c2ccccc2)C1>>COCO[C@H]1CCN(C[C@H](c2ccccc2)N(C)c2ccc(C#N)cc2Cl)C1 -US20140100231A1,1,CCOC(=O)c1cnc(SC)nc1Cl.CO>>CCOC(=O)c1cnc(SC)nc1OC -US20050203158A1,1,CCCCN.CNC(=O)c1ccc([N+](=O)[O-])c(F)c1>>CCCCNc1cc(C(=O)NC)ccc1[N+](=O)[O-] -US20100168414A1,6,O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(OCc3ccccc3)cc2)N1c1ccc(F)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(O)cc2)N1c1ccc(F)cc1 -US20060025433A1,1,COC(=O)c1cccc(C=O)c1.NC1CCC(CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+](=O)[O-])CC1>>COC(=O)c1cccc(CNC2CCC(CNc3nc(NCc4ccccc4OC(F)(F)F)ncc3[N+](=O)[O-])CC2)c1 -US07790763B2,1,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(O)CC1.CCOC(=O)c1ccc(O)cc1>>CCOC(=O)c1ccc(OC2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OC(C)C)CC2)cc1 -US20080058384A1,2,CC1=C(C(=O)O)C(c2ccc(C(F)(F)F)cc2F)CC(=O)N1C.Cc1n[nH]c2ccc(N)cc12>>CC1=C(C(=O)Nc2ccc3[nH]nc(C)c3c2)C(c2ccc(C(F)(F)F)cc2F)CC(=O)N1C -US20050107400A1,9,Fc1ccc(-c2nn3cc(CBr)ccc3c2-c2ccnc(NC3CCCC3)n2)cc1>>Cc1ccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nn2c1 -US06225495B1,3,CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Cc1c(F)c(F)c(COC(=O)[C@@H]2[C@@H](C=O)C2(C)C)c(F)c1F>>C/C=C\[C@@H]1[C@@H](C(=O)OCc2c(F)c(F)c(C)c(F)c2F)C1(C)C -US05455255,1,CC(C)O.CC(C)c1cc(O)cc2c1C(=O)N(c1c(F)c(F)nc(F)c1F)S2(=O)=O>>CC(C)Oc1cc(C(C)C)c2c(c1)S(=O)(=O)N(c1c(F)c(F)nc(F)c1F)C2=O -US20140364414A1,3,Brc1cnc(N2CCOCC2)c2nc(COc3ccc4ccccc4n3)cn12.CC1(C)OB(c2cccnc2)OC1(C)C>>c1cncc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)c1 -US20150274756A1,4,C#Cc1cc(F)cc(F)c1N>>Fc1cc(F)c2[nH]ccc2c1 -US20150152109A1,2,CC(C)n1ncc2c1C(=O)NC1(CCNCC1)C2.Cc1n[nH]c2c(C)cc(C(=O)O)cc12>>Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)cc12 -US20090286778A1,2,CN(C)S(=O)(=O)Cl.O=C(CC1CCNCC1)Nc1ccc2cc1CCc1cccc(c1)Nc1ncc(Cl)c(n1)N2>>CN(C)S(=O)(=O)N1CCC(CC(=O)Nc2ccc3cc2CCc2cccc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US09150537B2,1,CC(=O)O.COC(=O)CCC/C=C\C[C@@H]1[C@@H](CO[Si](C)(C)C(C)(C)C)[C@H](OC2CCCCO2)C[C@@H]1O>>COC(=O)CCC/C=C\C[C@H]1[C@H](OC(C)=O)C[C@@H](OC2CCCCO2)[C@@H]1CO[Si](C)(C)C(C)(C)C -US08114872B2,7,CC(=O)c1ccc(Cl)nc1>>CC(O)c1ccc(Cl)nc1 -US06046206,9,NO.O=Cc1nc(NCc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1>>ON=Cc1nc(NCc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1 -US20080045562A1,2,CCO.Cc1ccc(C(=O)O)cc1O>>CCOC(=O)c1ccc(C)c(O)c1 -US08816090B2,1,BrCC1CCC1.CC(C)(C)OC(=O)N1CCC(COc2noc3cccc(O)c23)CC1>>CC(C)(C)OC(=O)N1CCC(COc2noc3cccc(OCC4CCC4)c23)CC1 -US20050245543A1,3,Cc1cc(C2CCCN2C)ccc1Br.O=Cc1ccc(B(O)O)cc1>>Cc1cc(C2CCCN2C)ccc1-c1ccc(C=O)cc1 -US20120238549A1,9,CC[C@@]1(O)CC[C@@]2(Cc3ccccc3)c3ccc(C(=O)Nc4cccnc4C)cc3COC(O)[C@H]2C1>>CC[C@@]1(O)CC[C@@]2(Cc3ccccc3)c3ccc(C(=O)Nc4cccnc4C)cc3COC[C@H]2C1 -US20140155594A1,4,BrCCCCBr.N[C@@H](CO)c1ccccc1>>OC[C@@H](c1ccccc1)N1CCCC1 -US20140056849A1,1,CC(C)C(=O)Cl.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F>>CCCS(=O)(=O)N(C(=O)C(C)C)c1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F -US20080167307A1,6,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(-c3ccc(F)cc3)cc2)cs1>>CC(C)(Sc1nc(CCOc2ccc(-c3ccc(F)cc3)cc2)cs1)C(=O)O -US06323235B1,6,COc1cccc2c(CSC(c3ccccc3)c3ccccc3)coc12>>Oc1cccc2c(CSC(c3ccccc3)c3ccccc3)coc12 -US20060111337A1,6,COc1ncccc1C(F)(F)F>>Oc1ncccc1C(F)(F)F -US20030229058A1,7,COc1ccc([N+](=O)[O-])cc1-c1cccc(CN)c1>>COc1ccc(N)cc1-c1cccc(CN)c1 -US04125732,6,COC(=O)C(Oc1ccc2c(c1)CCC2)c1ccc(OCCCOc2ccc(Cl)cc2)cc1>>O=C(O)C(Oc1ccc2c(c1)CCC2)c1ccc(OCCCOc2ccc(Cl)cc2)cc1 -US20080275097A1,7,COc1ccc(CNc2ccc3c(C(=O)OC(C)(C)C)nn(Cc4ccc(OC)cc4)c3n2)cc1>>COc1ccc(CNc2ccc3c(CO)nn(Cc4ccc(OC)cc4)c3n2)cc1 -US20110130406A1,6,COc1ccc(Cn2nc(O[C@H]3CCCN(C(=O)OC(C)(C)C)C3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(O[C@H]3CCCNC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1 -US08063035B2,3,O=Cc1ccc(F)cc1Br.[Mg+]CCC1OCCCO1>>OC(CCC1OCCCO1)c1ccc(F)cc1Br -US20060281695A1,1,CCOCCl.O=S(=O)(Nc1ccc(Cl)cc1Oc1ccc(Cl)cc1Cl)C(F)(F)F>>CCOCN(c1ccc(Cl)cc1Oc1ccc(Cl)cc1Cl)S(=O)(=O)C(F)(F)F -US20150038574A1,1,CC1=C(CO)C(C)(C)CCC1.N#Cc1ccc(O)cc1F>>CC1=C(COc2ccc(C#N)c(F)c2)C(C)(C)CCC1 -US07115741B2,1,CCc1cc2c(Cl)ncnc2s1.C[C@H]1CN(C(=O)OC(C)(C)C)CCN1>>CCc1cc2c(N3CCN(C(=O)OC(C)(C)C)C[C@@H]3C)ncnc2s1 -US20100168080A1,2,CC(=O)Cl.COc1cc(OCC(O)CN2CCC(Oc3ccc(Cl)cc3)CC2)c(N)cc1Cl>>COc1cc(OCC(O)CN2CCC(Oc3ccc(Cl)cc3)CC2)c(NC(C)=O)cc1Cl -US20050131032A1,6,CCCCOc1ccc(C(=O)OCC)cc1>>CCCCOc1ccc(C(=O)O)cc1 -US20120277431A1,3,C#C[Si](C)(C)C.O=c1ccn(-c2cccc(C(F)(F)F)c2)nc1Br>>C[Si](C)(C)C#Cc1nn(-c2cccc(C(F)(F)F)c2)ccc1=O -US06391916B1,3,C#CCCCCC#C.O=CC(Br)=Cc1ccccc1>>C#CCCCCC#CC(O)/C(Br)=C/c1ccccc1 -US20100160373A1,1,CI.Nc1cc2c(cc1Br)CCC(=O)N2>>CN1C(=O)CCc2cc(Br)c(N)cc21 -US08148523B2,2,NC(=O)c1cccn1N.O=C(N=C=S)c1ccccc1>>NC(=O)c1cccn1NC(=S)NC(=O)c1ccccc1 -US20050282864A1,2,C1CCNC1.CC(C)N1CC[C@H](Oc2ccc3[nH]c(C(=O)O)cc3c2)C1>>CC(C)N1CC[C@H](Oc2ccc3[nH]c(C(=O)N4CCCC4)cc3c2)C1 -US20130310384A1,2,CC[C@H](NCc1ccc(C(=O)OC)cc1)c1ccccc1.O=C(Cl)c1ccc(Cl)cc1>>CC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)OC)cc1)C(=O)c1ccc(Cl)cc1 -US20130252890A1,1,CNCCCCS(=O)(=O)CCC(F)(F)C(F)(F)F.Oc1ccc2c(c1)CCCC(c1ccc(F)c(F)c1)=C2CCCCCCBr>>CN(CCCCCCC1=C(c2ccc(F)c(F)c2)CCCc2cc(O)ccc21)CCCCS(=O)(=O)CCC(F)(F)C(F)(F)F -US04410537,6,CCOC(=O)CCCCOc1cccc(O)c1C=O>>O=Cc1c(O)cccc1OCCCCC(=O)O -US20060049397A1,1,CC(=O)Nc1ccc(C(C)C)cc1.CC(C)c1ccc(I)cc1>>CC(=O)N(c1ccc(C(C)C)cc1)c1ccc(C(C)C)cc1 -US05416231,8,COC(=O)C1CC1CC#CCO>>COC(=O)C1CC1CC#CC=O -US05721230,6,CCOC(=O)C[C@H]1CCn2c(cc3ccccc32)C1>>O=C(O)C[C@H]1CCn2c(cc3ccccc32)C1 -US20110039824A1,2,CC(C)OC(=O)C1=CNCC(C)(C)c2c1[nH]c1ccccc21.O=C(Cl)c1ccc(CCl)cc1>>CC(C)OC(=O)C1=CN(C(=O)c2ccc(CCl)cc2)CC(C)(C)c2c1[nH]c1ccccc21 -US06583180B2,1,Cc1c(N)cccc1[N+](=O)[O-].O=Cc1ccc(Oc2ccc(CCC(=O)O)cc2)cc1>>Cc1c(NCc2ccc(Oc3ccc(CCC(=O)O)cc3)cc2)cccc1[N+](=O)[O-] -US20040102636A1,7,COc1cc(C(C)(C)C)ccc1[N+](=O)[O-]>>COc1cc(C(C)(C)C)ccc1N -US20060079548A1,2,COC1CCN(C(=O)c2cc3nccc(Oc4ccc5c(C(=O)O)c(C)oc5c4)c3s2)C1.NCCO>>COC1CCN(C(=O)c2cc3nccc(Oc4ccc5c(C(=O)NCCO)c(C)oc5c4)c3s2)C1 -US20150238558A1,6,C[C@H](c1ccccc1F)N(Cc1ccc(C(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)OC(C)(C)C)C2)cc1)C(=O)[C@@H]1Cc2ccccc2CN1>>C[C@H](c1ccccc1F)N(Cc1ccc(C(=O)N[C@@H]2CN[C@H](C(=O)N[C@@H]3CCCc4ccccc43)C2)cc1)C(=O)[C@@H]1Cc2ccccc2CN1 -US20110172245A1,1,O=C(Nc1ccc(C(F)(F)F)cc1)c1cccc(O)c1.O=[N+]([O-])c1ccc(F)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)c1cccc(Oc2ccc([N+](=O)[O-])cc2)c1 -US08017602B2,6,COC(CN(C(=O)CCOCCc1cccc(-c2cnco2)c1)C1CCCCC1)OC>>O=CCN(C(=O)CCOCCc1cccc(-c2cnco2)c1)C1CCCCC1 -US08022062B2,3,CC(C)(C)OC(=O)NCc1ccc(Br)cc1.OB(O)c1ccncc1>>CC(C)(C)OC(=O)NCc1ccc(-c2ccncc2)cc1 -US08969375B2,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Cc1ccc(S(=O)(=O)n2c(I)cc3c(Cl)ccnc32)cc1>>Cc1ccc(S(=O)(=O)n2c(C3=CCN(C(=O)OC(C)(C)C)CC3)cc3c(Cl)ccnc32)cc1 -US20090062360A1,1,CCOC(=O)CBr.O=C1NC2(CCCC2)N=C1c1ccc(C(F)(F)F)cc1>>CCOC(=O)CN1C(=O)C(c2ccc(C(F)(F)F)cc2)=NC12CCCC2 -USRE040558E1,1,COC(=O)c1c(C)cccc1CBr.OCCCOCc1ccc2ccccc2n1>>COC(=O)c1c(C)cccc1COCCCOCc1ccc2ccccc2n1 -US08435980B2,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2cc(-c3cn(S(=O)(=O)c4ccccc4)c4ncc(O)cc34)cc(Cl)n2)CC1.CCO>>CCOc1cnc2c(c1)c(-c1cc(Cl)nc(N[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)c1)cn2S(=O)(=O)c1ccccc1 -US20070032485A1,1,CCOC(=O)CCCBr.CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(O)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)CCCOc1cnc(N[C@H]2C[C@@H](CC)N(C(=O)OCC)c3ccc(OC)nc32)nc1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20120041018A1,7,COc1cccc(C=CCC(=O)O)c1OC>>COc1cccc(CCCC(=O)O)c1OC -US07326791B2,2,Cc1cc(C(=O)O)ccc1C(=O)N1CCCC1.NC(=O)NCCCC[C@H](N)c1nc2cc(Cl)ccc2[nH]1>>Cc1cc(C(=O)N[C@@H](CCCCNC(N)=O)c2nc3cc(Cl)ccc3[nH]2)ccc1C(=O)N1CCCC1 -US20040266839A1,1,CI.Cc1cccc(CNC(=O)c2ccc(-c3cc(-c4nnc(C)o4)ccc3C)cc2)c1>>Cc1cccc(CN(C)C(=O)c2ccc(-c3cc(-c4nnc(C)o4)ccc3C)cc2)c1 -US08487108B2,7,CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCC#N)c2ccc(F)c(Cl)c2)C1>>CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCCN)c2ccc(F)c(Cl)c2)C1 -US20120165310A1,1,CC1(C)CCC(CBr)O1.CC1(C)OB(c2cccc(O)c2)OC1(C)C>>CC1(C)CCC(COc2cccc(B3OC(C)(C)C(C)(C)O3)c2)O1 -US08012979B2,1,BrCC1CCC1.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)[nH]ccc2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CCC3)ccc2c1 -US20120252801A1,2,CC(C)(C)c1csc(N)n1.CCN1CC(C)(C)OC(=O)C1CC(=O)O>>CCN1CC(C)(C)OC(=O)C1CC(=O)Nc1nc(C(C)(C)C)cs1 -US20130005707A1,1,C[Si](C)(C)CCOCCl.O=[N+]([O-])c1ccc2cn[nH]c2c1>>C[Si](C)(C)CCOCn1ncc2ccc([N+](=O)[O-])cc21 -US20090170847A1,2,CCS(=O)(=O)Nc1ccc(CCN)cc1.O=C(O)c1ccnc2[nH]c(-c3ccc(Cl)cc3)nc12>>CCS(=O)(=O)Nc1ccc(CCNC(=O)c2ccnc3[nH]c(-c4ccc(Cl)cc4)nc23)cc1 -US20130158075A1,2,COC(=O)C1CCC(c2ncc(-c3ccc(N)cc3)o2)CC1.O=C=Nc1cccc(Cl)c1>>COC(=O)C1CCC(c2ncc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)o2)CC1 -US20090137499A1,8,COc1ccc(Cc2ccc(CO)cc2OCc2ccccc2)cc1>>COc1ccc(Cc2ccc(C=O)cc2OCc2ccccc2)cc1 -US08420645B2,3,Brc1ccc2ncccc2c1.C#CC(OCC)OCC>>CCOC(C#Cc1ccc2ncccc2c1)OCC -US04728647,7,O=C(COc1cc(-c2ccc([N+](=O)[O-])cc2)nc2ccccc12)N1CCOCC1>>Nc1ccc(-c2cc(OCC(=O)N3CCOCC3)c3ccccc3n2)cc1 -US20100041892A1,7,CC(C)Oc1ccc(CCC(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1>>CC(C)Oc1ccc(CCCO)c(Oc2ncc(C(F)(F)F)cc2Cl)c1 -US09126998B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOCC(O)CN>>CCOCC(O)CNC(=O)OC(C)(C)C -US04630896,9,BrC(Br)(Br)Br.CCCCC[C@@H]1CC[C@@H](CCO)CC1>>CCCCC[C@@H]1CC[C@@H](CCBr)CC1 -US20030100580A1,2,CN(C)CCOc1cc(N)ccc1Cl.O=S(=O)(Cl)c1c(Cl)cc(C(F)(F)F)cc1Cl>>CN(C)CCOc1cc(NS(=O)(=O)c2c(Cl)cc(C(F)(F)F)cc2Cl)ccc1Cl -US07696213B2,3,COc1ccc(B(O)O)cn1.Cc1nc(N)nc2c1cc(Br)c(=O)n2[C@@H]1CC[C@@H](O)CC1>>COc1ccc(-c2cc3c(C)nc(N)nc3n([C@@H]3CC[C@@H](O)CC3)c2=O)cn1 -US08546377B2,1,Cc1cccc(Br)c1O.OCC[C@H]1CN(Cc2ccccc2)CCN1>>Cc1cccc(Br)c1OCC[C@H]1CN(Cc2ccccc2)CCN1 -US06881844B2,1,CC(C)I.Cc1ccc2c(C(=O)C(F)(F)F)c[nH]c2c1>>Cc1ccc2c(C(=O)C(F)(F)F)cn(C(C)C)c2c1 -US20100004222A1,2,Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)O.Nc1nccc2cccnc12>>Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)Nc1nccc2cccnc12 -US04154834,2,CCO.O=C(O)C=Cc1cnc2ccccc2c1>>CCOC(=O)C=Cc1cnc2ccccc2c1 -US20050124620A1,7,Cc1ccc(S(=O)(=O)n2cc(/C=C/c3cccnc3)c3ccccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(CCc3cccnc3)c3ccccc32)cc1 -US05045549,1,CN1CC2CC1CN2.O=C(O)c1cn(-c2ccc(F)cc2F)c2cc(Cl)c(F)cc2c1=O>>CN1CC2CC1CN2c1cc2c(cc1F)c(=O)c(C(=O)O)cn2-c1ccc(F)cc1F -US08686048B2,3,COc1ccc(Cl)c(B(O)O)c1.Nc1ccc(Br)cc1>>COc1ccc(Cl)c(-c2ccc(N)cc2)c1 -US04283531,3,CC1(C)S[C@@H]2[C@@H](Br)C(=O)N2[C@H]1C#N.O=Cc1ccccc1>>CC1(C)S[C@@H]2[C@@H](C(O)c3ccccc3)C(=O)N2[C@H]1C#N -US04283531,3,CC1(C)S[C@@H]2[C@@H](Br)C(=O)N2[C@H]1C#N.O=Cc1ccccc1>>CC1(C)S[C@@H]2[C@H](C(O)c3ccccc3)C(=O)N2[C@H]1C#N -US20090191177A1,1,C1COCCN1.Cc1cc(Br)c2nc(O)cc(=O)n2c1>>Cc1cc(Br)c2nc(N3CCOCC3)cc(=O)n2c1 -US09156840B2,1,COC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1.Cn1c(=O)n(CCCI)c2ccccc21>>COC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCn4c(=O)n(C)c5ccccc54)CC3)C2=O)c1 -US09108903B2,2,COC(=O)c1ccc(N)cc1.O=C(Cl)c1ccc(C(F)(F)F)cc1F>>COC(=O)c1ccc(NC(=O)c2ccc(C(F)(F)F)cc2F)cc1 -US20110251204A1,6,CC[C@H](C)[C@@H](CN(C(=O)C1CC1c1ccccn1)c1ccc(-c2ccc(COC)cc2)cc1)NC(=O)OC(C)(C)C>>CC[C@H](C)[C@H](N)CN(C(=O)[C@@H]1C[C@H]1c1ccccn1)c1ccc(-c2ccc(COC)cc2)cc1 -US05491152,1,N#CCCl.O=C(CS)c1ccccc1>>N#CCSCC(=O)c1ccccc1 -US08716303B2,6,CC(C)(C)OC(=O)N1CCC(F)(C(CC#N)n2cc(-c3ncnc4c3ccn4COCC[Si](C)(C)C)cn2)C1>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C(CC#N)C4(F)CCNC4)c3)ncnc21 -US06214835B1,6,O=C1c2ccccc2C(=O)N1CCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>NCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl -US20140288069A1,1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NCC(O)C1CCCCC1>>OC(CNc1ccc2ncc(-c3cc4ccccc4o3)n2n1)C1CCCCC1 -US06706751B2,3,C#CCCCO.CC(C)(C)OC(=O)N1CCCc2cc(OS(=O)(=O)C(F)(F)F)ccc21>>CC(C)(C)OC(=O)N1CCCc2cc(C#CCCCO)ccc21 -US07879844B2,2,N#CCN.O=C(O)C12CC3CC(C1)C(n1c(=O)[nH]c4cnc5[nH]ccc5c41)C(C3)C2>>N#CCNC(=O)C12CC3CC(C1)C(n1c(=O)[nH]c4cnc5[nH]ccc5c41)C(C3)C2 -US05283240,2,COC(=O)CCCC1(C)OCCO1.NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21>>CC1(CCCC(=O)NNC(=O)N2Cc3ccccc3Oc3ccc(Cl)cc32)OCCO1 -US08829035B2,1,CN(C)CCN.O=[N+]([O-])c1cc(-c2nc3ccccc3o2)ccc1F>>CN(C)CCNc1ccc(-c2nc3ccccc3o2)cc1[N+](=O)[O-] -US06100254,6,COc1cccc(C(=O)c2ccc(Cl)cc2N)c1>>Nc1cc(Cl)ccc1C(=O)c1cccc(O)c1 -US20120004164A1,2,Cc1nc(N2CCN(Cc3ccc(C(F)(F)F)cc3)C2=O)sc1C(=O)O.NCc1ccccc1>>Cc1nc(N2CCN(Cc3ccc(C(F)(F)F)cc3)C2=O)sc1C(=O)NCc1ccccc1 -US20150133446A1,1,C[O-].Fc1ccc2nc(-c3cn4nc(Br)sc4n3)sc2c1>>COc1nn2cc(-c3nc4ccc(F)cc4s3)nc2s1 -US20110319424A1,8,Cc1cc(C)nc(CO)c1>>Cc1cc(C)nc(C=O)c1 -US20060100262A1,7,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(=O)N(CCN(C)C)Cc1ccoc1-3>>COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCN(CCN(C)C)Cc1ccoc1-3 -US20030187301A1,7,CCc1cc2c(cc1C(C)=O)CC(NC(=O)C(F)(F)F)C2>>CCc1cc2c(cc1CC)CC(NC(=O)C(F)(F)F)C2 -US20150072969A1,1,Cc1cc(O)cc(C)c1Br.OC1CCSCC1>>Cc1cc(OC2CCSCC2)cc(C)c1Br -US20090312310A1,6,COC(=O)[C@@H]1CNC(=O)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC(=O)NC[C@H]1C(=O)O -US03944615,7,O=C(O)c1ccc([N+](=O)[O-])cc1>>Nc1ccc(C(=O)O)cc1 -US09018214B2,6,CN(c1ccccc1)c1cc2c(cn1)C(C)(C)CN2C(=O)OC(C)(C)C>>CN(c1ccccc1)c1cc2c(cn1)C(C)(C)CN2 -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(O)Cc1ccccc1C(=O)O>>Cc1nc(NC(=O)Cc2ccccc2C(=O)O)sc1C(=O)NCc1ccccc1 -US07582626B2,2,CCOC(=O)C1CC=CCC1NCc1ccc(F)cc1.CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(CC(=O)O)N2>>CCOC(=O)C1CC=CCC1N(Cc1ccc(F)cc1)C(=O)CC1=NS(=O)(=O)c2cc(NS(C)(=O)=O)ccc2N1 -US07737166B2,1,CN(C)[C@H]1CCNC1.Cc1c(-c2ccccc2)c(F)c2oc(N3CC(O)C3)nc2c1C#N>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(N3CC(O)C3)nc2c1C#N -US04898874,2,O=C(O)Cc1cc(Cl)cc2c(-c3ccccc3)onc12.c1ccc(N2CCNCC2)cc1>>O=C(Cc1cc(Cl)cc2c(-c3ccccc3)onc12)N1CCN(c2ccccc2)CC1 -US08124649B2,3,CC1(C)OB(c2ccc(N3CCNCC3)nc2)OC1(C)C.O=C1Nc2ccc(Cl)cc2C1=Cc1ccc(Br)o1>>O=C1Nc2ccc(Cl)cc2C1=Cc1ccc(-c2ccc(N3CCNCC3)nc2)o1 -US20130331382A1,2,CCOc1cc(=O)n(C)cc1-c1cc(N)ccc1Oc1ccc(Cl)cc1.CCS(=O)(=O)Cl>>CCOc1cc(=O)n(C)cc1-c1cc(NS(=O)(=O)CC)ccc1Oc1ccc(Cl)cc1 -US05288726,1,O=C(C(Br)c1ccccc1Cl)C(F)(F)F.c1cc2c(s1)CCNC2>>O=C(C(c1ccccc1Cl)N1CCc2sccc2C1)C(F)(F)F -US20130317024A1,9,COc1ccc(CC(=O)O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O.N>>COc1ccc(CC(N)=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O -US20140179715A1,1,N.O=Cc1ccc(Oc2ccc(F)c(F)c2)c(F)c1>>NCc1ccc(Oc2ccc(F)c(F)c2)c(F)c1 -US20040116480A1,7,COC(=O)c1cscc1OC>>COc1cscc1CO -US05635197,7,CN1C(=O)CC[C@]2(C)c3ccc(C=Cc4ccccc4)cc3CC[C@@H]12>>CN1C(=O)CC[C@]2(C)c3ccc(CCc4ccccc4)cc3CC[C@@H]12 -US04806685,1,CN(C)CCO.COc1ccc(C(=C(c2ccccc2)c2ccc(F)cc2)C(F)(F)F)cc1>>COc1ccc(C(=C(c2ccccc2)c2ccc(OCCN(C)C)cc2)C(F)(F)F)cc1 -US20140142083A1,1,COC(=O)c1ccnc(Cl)c1C.NC1CCOCC1>>COC(=O)c1ccnc(NC2CCOCC2)c1C -US20040122057A1,7,CCOC(C(=O)NCc1ccc(C(=N)N)cc1Oc1ccc([N+](=O)[O-])cn1)c1ccc(OC)cc1F>>CCOC(C(=O)NCc1ccc(C(=N)N)cc1Oc1ccc(N)cn1)c1ccc(OC)cc1F -US06924300B2,6,COC(=O)CCCCCC/C(=N\OCc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)c1ccc(Cl)cc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CCCCCCC(=O)O)c2ccc(Cl)cc2)cc1 -US05932582,1,Cc1cc(O)ccc1NC(=O)OC(C)(C)C.NC(=O)CBr>>Cc1cc(OCC(N)=O)ccc1NC(=O)OC(C)(C)C -US07999132B2,6,CC(C)(C)OC(=O)c1ccc(-c2cccc(Cl)c2)cc1NC(=O)c1ccc(F)cc1>>O=C(Nc1cc(-c2cccc(Cl)c2)ccc1C(=O)O)c1ccc(F)cc1 -US20100056515A1,1,CCC(CC)c1cccc2[nH]c(=O)[nH]c12.COc1ccc(CCl)cc1>>CCC(CC)c1cccc2c1[nH]c(=O)n2Cc1ccc(OC)cc1 -US20050154042A1,3,CC(C)(C)OC(=O)C[C@H]1C[C@@H](C=O)OC(C)(C)O1.CC(C)n1c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)NCCc1cccnc1>>CC(C)n1c(C=C[C@@H]2C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O2)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)NCCc1cccnc1 -US20060217382A1,2,COc1ccc(Nc2ncc(C(C)N)nn2)cc1.O=C(O)c1ccoc1>>COc1ccc(Nc2ncc(C(C)NC(=O)c3ccoc3)nn2)cc1 -US20100004292A1,2,COC(=O)c1nscc1N.O=C(Cl)c1ccc(Cl)s1>>COC(=O)c1nscc1NC(=O)c1ccc(Cl)s1 -US20110251173A1,3,CN(Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(Cl)c1)C(=O)CCCNC(=O)OC(C)(C)C.Nc1ncnc2c1C(=O)N(c1ccc(Br)cc1)CCO2>>CN(Cc1ccc(-c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)c(Cl)c1)C(=O)CCCNC(=O)OC(C)(C)C -US20050032786A1,2,CNCC(=O)OC(C)(C)C.O=C(O)CCc1cccc(-c2nc(=O)c3ccccc3s2)n1>>CN(CC(=O)OC(C)(C)C)C(=O)CCc1cccc(-c2nc(=O)c3ccccc3s2)n1 -US20120252761A1,6,CCS(=O)(=O)c1cccc(-c2cc(Cl)c(OC)c3[nH]c4ncc(C)cc4c23)c1>>CCS(=O)(=O)c1cccc(-c2cc(Cl)c(O)c3[nH]c4ncc(C)cc4c23)c1 -US20140030529A1,3,O=C(Cl)c1ccccc1.c1ccccc1>>O=C(c1ccccc1)c1ccccc1 -US08349831B2,7,COC(=O)C1CCN(c2ccc(C=O)cc2[N+](=O)[O-])CC1>>COC(=O)C1CCN(c2ccc(C=O)cc2N)CC1 -US05614550,7,COCc1cccc(C=CC(O)c2ccccc2)c1NC(=O)CC1c2ccccc2Oc2ccccc21>>COCc1cccc(CCC(O)c2ccccc2)c1NC(=O)CC1c2ccccc2Oc2ccccc21 -US06667404B2,1,CC(C)c1nc(CCl)cs1.CN>>CNCc1csc(C(C)C)n1 -US20090074675A1,1,Cc1cc(N)c2cn[nH]c2c1.Fc1ccc(I)c(F)c1>>Cc1cc(N)c2cnn(-c3ccc(F)cc3F)c2c1 -US07211577B2,1,CC(C)(C)OC(=O)N1CCNCC1.COc1ccc(-c2cc(COS(C)(=O)=O)c(=O)n(Cc3ccc(F)cc3)n2)cc1F>>COc1ccc(-c2cc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(=O)n(Cc3ccc(F)cc3)n2)cc1F -US07294635B2,2,CCOC(=O)NS(=O)(=O)c1ccc(Cl)s1.Nc1ccc(-n2ccc3cc(NC4CC4)c(F)cc3c2=O)cc1>>O=C(Nc1ccc(-n2ccc3cc(NC4CC4)c(F)cc3c2=O)cc1)NS(=O)(=O)c1ccc(Cl)s1 -US04987132,2,CC(C)(C)OC(=O)N1C(C(=O)O)CSC1c1cccnc1.NNc1ccccc1>>CC(C)(C)OC(=O)N1C(C(=O)NNc2ccccc2)CSC1c1cccnc1 -US07851473B2,2,CC(=O)N(C)c1ccc(NC(=O)OCC(Cl)(Cl)Cl)cn1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>CC(=O)N(C)c1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)cn1 -US20140235609A1,6,CC(C)(C)OC(=O)NC1CCN(c2ccc(C(N)=O)cn2)CC1>>NC(=O)c1ccc(N2CCC(N)CC2)nc1 -US08309581B2,1,BrCC1CCCCC1.COC(=O)c1ccccc1-c1nc2cc(F)c(F)cc2[nH]1>>COC(=O)c1ccccc1-c1nc2cc(F)c(F)cc2n1CC1CCCCC1 -US08143251B2,2,Cc1csc([C@@H](C)N)n1.O=C(O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncccc6c5)CC4)n3n2)cc1>>Cc1csc([C@@H](C)NC(=O)c2ccc(-c3cnc4nnc(C5(c6ccc7ncccc7c6)CC5)n4n3)cc2)n1 -US20050137231A1,7,COc1cc2oc(=O)c(-c3ccc(C(F)(F)F)cc3)c(Cc3ccc(OC(=O)C(C)(C)C)cc3)c2cc1C>>COc1cc2oc(=O)c(-c3ccc(C(F)(F)F)cc3)c(Cc3ccc(O)cc3)c2cc1C -US20090093481A1,1,Fc1ccc(Nc2nc(Cl)nc(Cl)n2)cc1C(F)(F)F.NN=Cc1ccc(OC(F)(F)F)cc1>>Fc1ccc(Nc2nc(Cl)nc(NN=Cc3ccc(OC(F)(F)F)cc3)n2)cc1C(F)(F)F -USRE041315E1,1,CCI.FC(F)(F)c1cc(Cl)cc(N2CCNCC2)c1>>CCN1CCN(c2cc(Cl)cc(C(F)(F)F)c2)CC1 -US20040209921A1,2,CC(O)c1ccccn1.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)c1ccccn1 -US20060287315A1,7,O=C1NCCN1c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2CCNC2=O)cc1 -US20060122176A1,1,CCN.O=C1NC(=O)C(=Cc2ccc([N+](=O)[O-])c(F)c2)S1>>CCNc1cc(C=C2SC(=O)NC2=O)ccc1[N+](=O)[O-] -US06875775B2,7,CCOC(=O)CNc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccccc2)cc1>>OCCNc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccccc2)cc1 -US05346896,7,COc1ccccc1N1CCN(C(=O)C(Oc2ccccc2)c2ccccc2)CC1>>COc1ccccc1N1CCN(CC(Oc2ccccc2)c2ccccc2)CC1 -US08188106B2,3,C#C[Mg+].CCOCCOc1cc(C=O)cc2c1C(C)(C)CCC2(C)C>>C#CC(O)c1cc(OCCOCC)c2c(c1)C(C)(C)CCC2(C)C -US20100075976A1,1,CN(CC=O)C(=O)OC(C)(C)C.COCc1ccc(-c2nccnc2N2CCNCC2)cc1>>COCc1ccc(-c2nccnc2N2CCN(CCN(C)C(=O)OC(C)(C)C)CC2)cc1 -US20120316147A1,3,Cc1nc(C(C)(C)NC(=O)c2cccc(Br)n2)no1.OB(O)c1ccc(F)c(Cl)c1>>Cc1nc(C(C)(C)NC(=O)c2cccc(-c3ccc(F)c(Cl)c3)n2)no1 -US20060116400A1,6,CC(C)(C)OC(=O)C1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1>>O=C(O)C1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1 -US08394858B2,6,CC(NC(=O)C1(O)CCC(NC(=O)OC(C)(C)C)CC1)c1ccccc1>>CC(NC(=O)C1(O)CCC(N)CC1)c1ccccc1 -US07935830B2,1,CC1c2ccc(O)cc2C2CNCC12.Fc1ccccc1CBr>>CC1c2ccc(OCc3ccccc3F)cc2C2CNCC12 -US08501746B2,2,Cc1nc(-n2ccc(OCc3ccccc3)cc2=O)sc1C(=O)O.Cc1nc(CN)cs1>>Cc1nc(CNC(=O)c2sc(-n3ccc(OCc4ccccc4)cc3=O)nc2C)cs1 -US20100056783A1,8,CC(C)N(C(=O)C[C@H]1C[C@@H](CO)OC(C)(C)O1)C(C)C>>CC(C)N(C(=O)C[C@H]1C[C@@H](C=O)OC(C)(C)O1)C(C)C -US05631206,7,Cc1ccc([N+](=O)[O-])c(-c2nc(C(F)(F)F)cs2)c1>>Cc1ccc(N)c(-c2nc(C(F)(F)F)cs2)c1 -US20070293521A1,1,CCOc1ccc(N)cc1.COc1ccc(Nc2nc(Cl)ncc2F)cc1OC>>CCOc1ccc(Nc2ncc(F)c(Nc3ccc(OC)c(OC)c3)n2)cc1 -US20030220350A1,7,O=[N+]([O-])c1ccc(Oc2ccccc2)nc1>>Nc1ccc(Oc2ccccc2)nc1 -US20080167345A1,3,NC(=O)c1cc(F)cc2cn(-c3ccc(Br)cc3)nc12.OB(O)c1cccnc1>>NC(=O)c1cc(F)cc2cn(-c3ccc(-c4cccnc4)cc3)nc12 -US08987251B2,9,COCCOc1ccnc(Cl)c1.NN>>COCCOc1ccnc(NN)c1 -US20140228361A1,7,CC(C)(C)OC(=O)N1CCc2ccncc2C1>>CC(C)(C)OC(=O)N1CCC2CCNCC2C1 -US20050014786A1,3,CC(C)(C)OC(=O)NC1Cc2cc(Br)ccc2N(Cc2ccccc2)C1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)NC1Cc2cc(-c3ccccc3)ccc2N(Cc2ccccc2)C1 -US20140275129A1,2,COc1cc2nc(-c3cc(OC)c(OC)c(OC)c3)nc(C(=O)O)c2cc1OC.Fc1ccc2c(c1)CCNC2>>COc1cc2nc(-c3cc(OC)c(OC)c(OC)c3)nc(C(=O)N3CCc4cc(F)ccc4C3)c2cc1OC -US20130053563A1,6,CC(C)(C)COC(=O)C(C)(C)C(=O)OC(C)(C)C>>CC(C)(C)COC(=O)C(C)(C)C(=O)O -US06313117B1,7,O=C(O)C1CCC(c2ccccc2)CC1>>OCC1CCC(c2ccccc2)CC1 -US06358995B1,6,CC(=O)OCc1cc2c(F)ccc(F)c2o1>>OCc1cc2c(F)ccc(F)c2o1 -US04036975,1,O=C(CBr)C12CC3CC(CC(C3)C1)C2.Sc1ccc(Cl)c(Cl)c1>>O=C(CSc1ccc(Cl)c(Cl)c1)C12CC3CC(CC(C3)C1)C2 -US20080004271A1,1,Cc1nc(Cl)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1.NC(=O)CS>>Cc1nc(SCC(N)=O)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1 -US05166344,1,CCc1nc(C)c[nH]1.O=[N+]([O-])c1ccc(F)cc1F>>CCc1nc(C)cn1-c1cc(F)ccc1[N+](=O)[O-] -US08222266B2,1,Cc1ncccc1-c1cc[nH]c(=O)n1.ClCCCCBr>>Cc1ncccc1-c1ccn(CCCCCl)c(=O)n1 -US20030055251A1,3,COc1cccc(B(O)O)c1.Nc1cnc(Br)cn1>>COc1cccc(-c2cnc(N)cn2)c1 -US07279580B2,3,CC(C)(O)c1ccn2c(-c3ccc(F)c(Cl)c3)cnc2c1F.OB(O)c1ccc(F)c(Cl)c1>>CC(C)(O)c1ccn2c(-c3ccc(F)c(-c4ccc(F)c(Cl)c4)c3)cnc2c1F -US20100240698A1,6,C=CCCCCCC(C)(C)C(=O)OCC>>C=CCCCCCC(C)(C)C(=O)O -US05212184,2,Fc1c(F)c(F)c(OC2CCNCC2)c(F)c1F.O=C(Cl)CCl>>O=C(CCl)N1CCC(Oc2c(F)c(F)c(F)c(F)c2F)CC1 -US20030171377A1,2,CC(=O)Cl.COC(=O)[C@H](Cc1ccc(O)cc1)n1cccc1>>COC(=O)[C@H](Cc1ccc(OC(C)=O)cc1)n1cccc1 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.COc1ncc(B(O)O)c(OC)n1>>CCCNC(=O)c1nnc2c(-c3cnc(OC)nc3OC)cccc2c1N -US05475001,7,O=[N+]([O-])c1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1Cl>>Nc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1Cl -US06660738B2,1,CCCc1cnc(Cl)nc1.Fc1cc(F)c(COC[C@@H]2C[C@@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)CN2)cc1F>>CCCc1cnc(N2C[C@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@H]2COCc2cc(F)c(F)cc2F)nc1 -US20120226035A1,6,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3ncccc32)CC1>>O=c1ccc2ncccc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1 -US20120122931A1,9,COc1ccc2cc(-c3cccc(C(N)=O)c3)[nH]c2c1>>COc1ccc2cc(-c3cccc(C#N)c3)[nH]c2c1 -US08063046B2,2,COC(=O)c1ccc([N+](=O)[O-])c(C(=O)O)c1.Nc1ccc(Cl)cc1>>COC(=O)c1ccc([N+](=O)[O-])c(C(=O)Nc2ccc(Cl)cc2)c1 -US04877787,1,CC(C)(C)c1ccc(CS)cc1.CC(C)(C)n1ncc(Br)c(Br)c1=O>>CC(C)(C)c1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Br)cc1 -US20090054453A1,2,CN1CCN(c2cccc3c2CC[C@H](N)C3)CC1.O=S(=O)(Cl)c1cccc(Cl)c1>>CN1CCN(c2cccc3c2CC[C@H](NS(=O)(=O)c2cccc(Cl)c2)C3)CC1 -US20100113780A1,3,CC1(C)Cc2cc(B(O)O)ccc2O1.CCCc1nc(C)c(Br)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(C)c(-c2ccc3c(c2)CC(C)(C)O3)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US20090082329A1,7,CSc1nccc(C=O)n1>>CSc1nccc(CO)n1 -US20150031670A1,2,NCc1cccc(F)c1.O=C(O)C1(O)CCCN(CC2CCCCC2)C1=O>>O=C(NCc1cccc(F)c1)C1(O)CCCN(CC2CCCCC2)C1=O -US08461134B2,6,O=C(Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(Br)c1)C(F)(F)F>>Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(Br)c1 -US06486180B1,4,C=CC(Cc1ccccc1)NC(=O)OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>O=C(NC(Cc1ccccc1)C1CO1)OCc1ccccc1 -US20060046999A1,6,CC(C)(C)OC(=O)NCCOc1cc(F)c(-n2c(N)c(C(=O)c3ccc(F)cc3)ccc2=O)c(F)c1>>Nc1c(C(=O)c2ccc(F)cc2)ccc(=O)n1-c1c(F)cc(OCC[NH3+])cc1F -US20100292188A1,8,COC(=O)C1CC(O)C(Br)C1>>COC(=O)C1CC(=O)C(Br)C1 -US20030195219A1,2,NCCN1CCN(c2ccccc2)CC1.O=C(Cl)Cc1cccc([N+](=O)[O-])c1>>O=C(Cc1cccc([N+](=O)[O-])c1)NCCN1CCN(c2ccccc2)CC1 -US20110230521A1,2,CCNCC.Cc1c(C(=O)NC(CC(=O)Cl)c2cccc(Br)c2)cnn1-c1ccc(Cl)c(Cl)c1>>CCN(CC)C(=O)CC(NC(=O)c1cnn(-c2ccc(Cl)c(Cl)c2)c1C)c1cccc(Br)c1 -US20020115853A1,3,O=c1[nH]c2ccc(Br)cc2s1.OB(O)c1cccc(Cl)c1>>O=c1[nH]c2ccc(-c3cccc(Cl)c3)cc2s1 -US20140364432A1,2,C[C@@H]1CCCN[C@@H]1CNc1ccc(C(F)(F)F)cn1.Cc1ccc(-n2ccnc2)c(C(=O)O)c1>>Cc1ccc(-n2ccnc2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(C(F)(F)F)cn2)c1 -US20040192708A1,2,CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(N)cc3)nc21.Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(NS(=O)(=O)c4c(C)cc(C)cc4C)cc3)nc21 -US20110183954A1,7,O=[N+]([O-])c1cn(CC(F)(F)F)cn1>>Nc1cn(CC(F)(F)F)cn1 -US20150158863A1,2,CCC(Oc1ccc(OC(F)(F)F)cc1)C(=O)Cl.O=C1CNc2ncccc2N1>>CCC(Oc1ccc(OC(F)(F)F)cc1)C(=O)N1CC(=O)Nc2cccnc21 -US20100331293A1,1,CC(C)(C)OC(=O)[C@H]1CCCN1.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>Cc1c(N2CCC[C@@H]2C(=O)OC(C)(C)C)nc2cc(F)cc(F)c2c1Cl -US04263302,6,CCOC(=O)c1cn(CC)c2c(c1=O)C(=O)CCC2>>CCn1cc(C(=O)O)c(=O)c2c1CCCC2=O -US20120172351A1,3,Cc1cccc(C)c1B(O)O.O=Cc1cccc(Br)c1O>>Cc1cccc(C)c1-c1cccc(C=O)c1O -US20090111808A1,1,Cc1ccc(-c2ccc(O)cc2)cc1.ClCCCBr>>Cc1ccc(-c2ccc(OCCCCl)cc2)cc1 -US20080318933A1,1,CC(C)(C)OC(=O)N1CCC(n2ccc3cc(Br)ccc32)CC1.O=S([O-])c1ccccc1>>CC(C)(C)OC(=O)N1CCC(n2ccc3cc(S(=O)(=O)c4ccccc4)ccc32)CC1 -US20090181929A1,3,C#C[Si](C)(C)C.CCN(CC1CCCC1)c1ncc(Br)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1>>CCN(CC1CCCC1)c1ncc(C#C[Si](C)(C)C)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1 -US08188139B2,6,COc1cc2c(cc1Cl)CN(C(=O)OC(C)(C)C)C2>>COc1cc2c(cc1Cl)CNC2 -US06514971B1,1,COc1cc2c(Cl)cnnc2cc1O.OCc1ccncc1>>COc1cc2c(Cl)cnnc2cc1OCc1ccncc1 -US20100144722A1,1,CC(C)(C)Nc1nc(Cl)cc(-c2ccccc2)n1.COC(=O)C1(c2ccc(N)cc2)CCC1>>COC(=O)C1(c2ccc(Nc3cc(-c4ccccc4)nc(NC(C)(C)C)n3)cc2)CCC1 -US20150166549A1,3,C#CCN(C)C(=O)OCc1ccccc1.CC(O)c1oc(=O)c2ccccc2c1Br>>CC(O)c1oc(=O)c2ccccc2c1C#CCN(C)C(=O)OCc1ccccc1 -US20110200586A1,1,CN(C1=NC(=O)C(=Cc2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)S1)C1CCNCC1.COCCBr>>COCCN1CCC(N(C)C2=NC(=O)C(=Cc3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)S2)CC1 -US20070212569A1,3,CCOc1ccc2cc(Br)ccc2c1.OB(O)c1ccccc1>>CCOc1ccc2cc(-c3ccccc3)ccc2c1 -US20070054916A1,3,Brc1ccc2ncncc2c1.COC(=O)c1ccc(C)c(B2OC(C)(C)C(C)(C)O2)c1>>COC(=O)c1ccc(C)c(-c2ccc3ncncc3c2)c1 -US20030096860A1,1,CC(=O)OCCCCBr.CCCCOc1c(O)c2cc(O)ccc2oc1=O>>CCCCOc1c(O)c2cc(OCCCCOC(C)=O)ccc2oc1=O -US05194431,2,CC1(C2(CO)CC2)OCCO1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC2(C3(C)OCCO3)CC2)cc1 -US20030181726A1,6,CC(CC(c1ccc(O)cc1)c1ccc(O)cc1)NCc1ccccc1>>CC(N)CC(c1ccc(O)cc1)c1ccc(O)cc1 -US04469693,1,N#CCCl.O=c1cccccc1N1CCNCC1>>N#CCN1CCN(c2cccccc2=O)CC1 -US05518653,1,CCCCCCCC[C@H]1CO[C@H](c2ccc(O)cc2)O[C@@H]1C.CCCC[C@H](F)C(=O)O>>CCCCCCCC[C@H]1CO[C@H](c2ccc(OC(=O)[C@@H](F)CCCC)cc2)O[C@@H]1C -US20100249179A1,1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CO.COC(=O)c1cc2c(Sc3ccc(O)cc3)cccc2s1>>COC(=O)c1cc2c(Sc3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)cccc2s1 -US06555552B2,3,COc1ccc(OC(F)(F)F)cc1C=O.C[Mg+]>>COc1ccc(OC(F)(F)F)cc1C(C)O -US07947676B2,1,ClCCOc1n[nH]c2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12.O[C@H]1CCNC1>>O[C@H]1CCN(CCOc2n[nH]c3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c23)C1 -US20060229336A1,6,CNS(=O)(=O)c1cccc(C(=O)OC)c1Cl>>CNS(=O)(=O)c1cccc(C(=O)O)c1Cl -US20140200227A1,3,COC(=O)c1nc(Br)cnc1N.OB(O)c1c(F)cccc1F>>COC(=O)c1nc(-c2c(F)cccc2F)cnc1N -US20100041657A1,2,Cc1c(Cl)cc(C(C)(C)C)c(O)c1C(=O)O.Nc1ccc(S(=O)(=O)C(F)(F)F)cc1Cl>>Cc1c(Cl)cc(C(C)(C)C)c(O)c1C(=O)Nc1ccc(S(=O)(=O)C(F)(F)F)cc1Cl -US04738975,1,COc1c(Cl)ccnc1C.OCC(F)(F)C(F)(F)F>>COc1c(OCC(F)(F)C(F)(F)F)ccnc1C -US04777179,7,CN(C)C(=O)c1csc(CO)c1>>CN(C)Cc1csc(CO)c1 -US20130040930A1,1,CN1CCNC1=O.Cc1cnc(N2CCN(C(=O)c3ccc(Cl)nn3)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCN(C)C4=O)nn3)CC2)c(C)c1 -US20060160832A1,7,O=[N+]([O-])c1ccc(Oc2ccnc(-c3ccccc3)c2)cc1>>Nc1ccc(Oc2ccnc(-c3ccccc3)c2)cc1 -US20130005716A1,7,COc1cc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)[C@@H](OC(C)=O)c2ccccc2)ccc1OC(F)F>>COc1cc([C@@H](O)Cc2c(Cl)c[n+]([O-])cc2Cl)ccc1OC(F)F -US20130053365A1,1,Cn1ncnc1Cc1n[nH]c(=O)c2cc(F)cc(CN)c12.O=Cc1ccc(F)cc1>>Cn1ncnc1Cc1n[nH]c(=O)c2cc(F)cc(C/N=C\c3ccc(F)cc3)c12 -US20060247210A1,2,CN(C)CCN.Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)Cl)cc2s1>>Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)NCCN(C)C)cc2s1 -US05338740,7,CC(=O)Oc1ccc2c(c1)CCC2=O>>CC(=O)Oc1ccc2c(c1)CCC2O -US20060084641A1,1,CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2c(Cl)ccc(Nc3c(Cl)c(=O)c3=O)c2O)CC1.Nc1ccccc1>>CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2c(Cl)ccc(Nc3c(Nc4ccccc4)c(=O)c3=O)c2O)CC1 -US05393768,2,CC(=O)Cl.CCCc1c(O)cccc1CN(C)C>>CCCc1c(CN(C)C)cccc1OC(C)=O -US20140357858A1,1,CC(C)(C)OC(=O)Nc1ccc(N)cc1.O=[N+]([O-])c1c(OS(=O)(=O)C(F)(F)F)ccc2ccccc12>>CC(C)(C)OC(=O)Nc1ccc(Nc2ccc3ccccc3c2[N+](=O)[O-])cc1 -US07521446B2,1,N[C@H]1CC[C@H](O)CC1.O=[N+]([O-])c1cnc(Cl)nc1NC1CCCC1>>O=[N+]([O-])c1cnc(N[C@@H]2CC[C@@H](O)CC2)nc1NC1CCCC1 -US07582773B2,1,Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cc(-c3ccc(O)cc3)ccc12.N#CCBr>>Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cc(-c3ccc(OCC#N)cc3)ccc12 -US20100197681A1,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O.O=C(Nc1nc2ccc(Br)cn2n1)c1cccnc1>>COc1cc(-c2ccc3nc(NC(=O)c4cccnc4)nn3c2)ccc1O -US20070197620A1,9,CC1COc2ccccc2C1(O)c1ncc[nH]1>>CC1COc2ccccc2C1c1ncc[nH]1 -US20150175557A1,6,CC(=O)NCCc1cc(Cl)ccc1S(N)(=O)=O>>NCCc1cc(Cl)ccc1S(N)(=O)=O -US20120288492A1,1,C1COCCN1.CSc1c(Cl)nc(Cl)nc1Cl>>CSc1c(Cl)nc(Cl)nc1N1CCOCC1 -US07659274B2,3,C#Cc1ccccc1.Nc1nccn2c(C3CCC3)nc(I)c12>>Nc1nccn2c(C3CCC3)nc(C#Cc3ccccc3)c12 -US20150284408A1,6,COc1ccc2ncc(=O)n(CCN3CCC(NC(=O)OC(C)(C)C)CC3)c2c1>>COc1ccc2ncc(=O)n(CCN3CCC(N)CC3)c2c1 -US20100130446A1,2,CNOC.CS(=O)(=O)c1ccc(C(C[C@H]2CCC3(C2)O[C@H](c2ccccc2)[C@@H](c2ccccc2)O3)C(=O)O)cc1Cl>>CON(C)C(=O)C(C[C@H]1CCC2(C1)O[C@H](c1ccccc1)[C@@H](c1ccccc1)O2)c1ccc(S(C)(=O)=O)c(Cl)c1 -US20150126488A1,7,CCOC(=O)CC1CCN(C2CC2)CC1>>OCCC1CCN(C2CC2)CC1 -US07517873B2,2,CCCCN(CCC(=O)OC(C)(C)C)c1nc(Cl)ncc1N>>CCCCN1CCC(=O)Nc2cnc(Cl)nc21 -US20020035104A1,3,CC(=O)Cl.CC(=O)n1c2ccccc2c2ccccc21>>CC(=O)c1ccc2c3ccccc3n(C(C)=O)c2c1 -US08030354B2,1,CCI.COC(=O)c1ccc(-c2cc(OC)ccc2F)c(CO)c1>>CCOCc1cc(C(=O)OC)ccc1-c1cc(OC)ccc1F -US05086055,1,CN1CC(CCCl)OC1=O.COc1ccc(N2CCNCC2)cc1OC>>COc1ccc(N2CCN(CCC3CN(C)C(=O)O3)CC2)cc1OC -US20090054431A1,4,CC(O)c1ccc(Oc2ccc(N)c(N)c2)cc1.O=CO>>CC(O)c1ccc(Oc2ccc3[nH]cnc3c2)cc1 -US04734410,9,O=C1NCC(c2ccccc2)CCC1Br.[N-]=[N+]=[N-]>>[N-]=[N+]=N[C@@H]1CC[C@@H](c2ccccc2)CNC1=O -US07173037B2,2,CCOC(=O)Cl.Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)nc(N)c1N>>CCOC(=O)Nc1c(N)nc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N -US05278152,1,CCOP(=O)(Cc1ccccc1C=O)OCC.NNC(N)=S>>CCOP(=O)(Cc1ccccc1C=NNC(N)=S)OCC -US05538976,1,BrCc1ccc2nonc2c1.N#Cc1ccc(Nc2cncnc2)cc1>>N#Cc1ccc(N(Cc2ccc3nonc3c2)c2cncnc2)cc1 -US20140378459A1,1,CC(C)(C)OC(=O)CBr.CC(C)(C)OC(=O)c1ccc(CCNC(=O)OCc2ccccc2)cc1>>CC(C)(C)OC(=O)CN(CCc1ccc(C(=O)OC(C)(C)C)cc1)C(=O)OCc1ccccc1 -US08026241B2,7,Nc1ncc(C(F)(F)F)cc1[N+](=O)[O-]>>Nc1cc(C(F)(F)F)cnc1N -US20100267688A1,6,N=C1NOC(=N)C1C1CCC2(CC1)OCCO2>>N=C1NOC(=N)C1C1CCC(=O)CC1 -US08119676B2,4,CC(C)(C)OC(=O)N1CCC(N)C1.ClCCN(CCCl)Cc1ccccc1>>CC(C)(C)OC(=O)N1CCC(N2CCN(Cc3ccccc3)CC2)C1 -US05668147,6,CCOC(=O)[C@@H]1CN(C(=O)OCc2ccccc2)C[C@H]1C(F)(F)F>>O=C(O)[C@@H]1CN(C(=O)OCc2ccccc2)C[C@H]1C(F)(F)F -US04623376,1,CNC.Cc1c(Cl)nnc(-c2ccccc2)c1C>>Cc1c(-c2ccccc2)nnc(N(C)C)c1C -US07332497B2,1,COCCBr.COc1cc(-c2nn(C3CCNC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C>>COCCN1CCC(n2nc(-c3ccc(NC(=O)c4cc5ccccc5n4C)c(OC)c3)c3c(N)ncnc32)C1 -US20110301143A1,2,CCOC(=O)Cn1nnc(-c2cnc(N3CCNCC3)s2)n1.O=C(Cl)c1cccc(F)c1C(F)(F)F>>CCOC(=O)Cn1nnc(-c2cnc(N3CCN(C(=O)c4cccc(F)c4C(F)(F)F)CC3)s2)n1 -US06045590,2,CC(=O)Cl.Cc1ccc2ccccc2c1O>>CC(=O)Oc1c(C)ccc2ccccc12 -US05151421,2,CCC(c1ccc(N)c([N+](=O)[O-])c1)n1ccnc1.Cc1ccccc1CC(=O)Cl>>CCC(c1ccc(NC(=O)Cc2ccccc2C)c([N+](=O)[O-])c1)n1ccnc1 -US03962378,6,CCOP(=O)(CCOC(C)=O)OCC>>CCOP(=O)(CCO)OCC -US04637821,1,NCCN.O=[N+]([O-])c1ccc(O)cc1Cl>>NCCNc1cc(O)ccc1[N+](=O)[O-] -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4ccc(F)cc4)ncnc32)CC1 -US20140243374A1,1,COC(=O)c1ccc(CBr)c(F)c1F.O=S(=O)(NC1CCCCC1O)c1ccc(Cl)cc1>>COC(=O)c1ccc(CN(C2CCCCC2O)S(=O)(=O)c2ccc(Cl)cc2)c(F)c1F -US20090227555A2,6,CCc1cnc(-c2cc(Cl)c(N3CCC(C(=O)OC)CC3)nc2NC)o1>>CCc1cnc(-c2cc(Cl)c(N3CCC(C(=O)O)CC3)nc2NC)o1 -US06268313B1,2,Cc1cc(O)cc(Cl)c1OCc1ccccc1.O=C(Cl)c1ccccc1>>Cc1cc(OC(=O)c2ccccc2)cc(Cl)c1OCc1ccccc1 -US20070060573A1,2,CCOc1ccc(Br)cc1C(=O)O.COC(=O)[C@H](N)Cc1c[nH]c2ccccc12>>CCOc1ccc(Br)cc1C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)OC -US20150018331A1,3,C#Cc1ccc(C#N)cc1.O=Cc1ccc(I)cc1>>N#Cc1ccc(C#Cc2ccc(C=O)cc2)cc1 -US20070167437A1,2,CCOc1nc(C)ncc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1.O=C(Cl)Cl>>CCOc1nc(C)ncc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)Cl -US06586436B2,2,C[C@H](CNc1ccccn1)N1CCN(c2cccc3c2OCCO3)CC1.N#Cc1ccc(C(=O)Cl)cc1>>C[C@H](CN(C(=O)c1ccc(C#N)cc1)c1ccccn1)N1CCN(c2cccc3c2OCCO3)CC1 -US08445684B2,1,CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(Br)c1.c1ccc(OCCC2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(N2CCC(CCOc3ccccc3)CC2)c1 -US20150284395A1,2,C#CCN.CCn1ncc2cc(-c3cc(=O)n4nc(C)c(C(=O)O)c4[nH]3)ccc21>>C#CCNC(=O)c1c(C)nn2c(=O)cc(-c3ccc4c(cnn4CC)c3)[nH]c12 -US08486962B2,1,FC(F)C(F)(F)CI.O=[N+]([O-])c1ccc(O)nc1>>O=[N+]([O-])c1ccc(OCC(F)(F)C(F)F)nc1 -US20100152450A1,1,C1CC2CNCC1C2.CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(Br)c1>>CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(N2CC3CCC(C3)C2)c1 -US08563565B2,7,Cc1cc(C(=O)O)cc(Cl)n1>>Cc1cc(CO)cc(Cl)n1 -US04167487,2,Cc1ncc[nH]1.O=C(Cl)c1ccccc1>>Cc1nccn1C(=O)c1ccccc1 -US20150252017A1,6,CCOC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1ccc(-c2ccc(F)cc2)n1>>O=C(NC(Cc1ccccc1)C(O)C(=O)O)c1cccnc1-n1ccc(-c2ccc(F)cc2)n1 -US20080139598A1,7,O=[N+]([O-])c1cc(-c2cccc(Cl)c2)ccc1NC1CCN(c2ncccn2)CC1>>Nc1cc(-c2cccc(Cl)c2)ccc1NC1CCN(c2ncccn2)CC1 -US06046227,6,CC(C)(CCc1ccc(Oc2ccc(C(N)=O)cc2)cc1)NC[C@H](O)COc1cnn(Cc2ccccc2)c1>>CC(C)(CCc1ccc(Oc2ccc(C(N)=O)cc2)cc1)NC[C@H](O)COc1cn[nH]c1 -US05371087,1,Fc1ccc(-n2cc(N3CCNCC3)c3ccccc32)cc1.O=C1N(CCCCBr)CSC12CCCCC2>>O=C1N(CCCCN2CCN(c3cn(-c4ccc(F)cc4)c4ccccc34)CC2)CSC12CCCCC2 -US20150152077A1,3,COC(=O)c1ccccc1B(O)O.COc1ccc2c(Br)cccc2c1>>COC(=O)c1ccccc1-c1cccc2cc(OC)ccc12 -US20150284395A1,4,CC(=O)CBr.N#CCC(N)=S>>Cc1csc(CC#N)n1 -US06534535B1,5,Brc1ccc2c(c1)CCN2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCc2cc(Br)ccc21 -US08293902B2,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCN(S(C)(=O)=O)CC1.Oc1cnc2[nH]ccc2c1>>COc1cc2c(Oc3cnc4[nH]ccc4c3)ncnc2cc1OCCCN1CCN(S(C)(=O)=O)CC1 -US20140005168A1,1,Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc(C(F)(F)F)c(F)n2)n1.OC1CNCCNC1>>Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc(C(F)(F)F)c(N3CCNCC(O)C3)n2)n1 -US04853376,7,N#CC1CN2CCC1CC2>>NCC1CN2CCC1CC2 -US20040235865A1,1,CC1CCCCN1.Fc1cc(F)c(-c2c(Cl)nc3nccn3c2Cl)c(F)c1>>CC1CCCCN1c1c(-c2c(F)cc(F)cc2F)c(Cl)nc2nccn12 -US06069149,1,CC(C)(C)OC(=O)NCCCN.O=[N+]([O-])c1c(Cl)nc2ccccc2c1Cl>>CC(C)(C)OC(=O)NCCCNc1c([N+](=O)[O-])c(Cl)nc2ccccc12 -US20150087639A1,2,COC(=O)/C=C(/C)N.O=C(Cl)CCc1cccc(F)c1>>COC(=O)/C=C(/C)NC(=O)CCc1cccc(F)c1 -US06562828B1,6,CCOC(=O)C1(COc2ccc3c(c2)CN(C(=N)N)CCC3)CCN(c2ccncc2)CC1>>N=C(N)N1CCCc2ccc(OCC3(C(=O)O)CCN(c4ccncc4)CC3)cc2C1 -US20040209886A1,7,CC(C)(C)OC(=O)C(C)(C)Oc1ccccc1Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)C(C)(C)Oc1ccccc1Oc1ccc(N)cc1 -US07803806B2,6,CCOC(=O)c1ccc(-c2ccnc(Nc3cccnc3)n2)s1>>O=C(O)c1ccc(-c2ccnc(Nc3cccnc3)n2)s1 -US07491819B1,2,CCOC(=O)c1nc2n(c(=O)c1O)CCOC2(C)C.NCc1ccc(F)cc1>>CC1(C)OCCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O -US20130296312A1,1,CN1CCN(c2cccc(N)c2)CC1.Fc1ccccc1CNc1cccn2nc(Cl)nc12>>CN1CCN(c2cccc(Nc3nc4c(NCc5ccccc5F)cccn4n3)c2)CC1 -US20130338140A1,7,C[C@H](O[Si](C)(C)C(C)(C)C)C(=O)c1cccc(C(F)(F)F)c1F>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](O)c1cccc(C(F)(F)F)c1F -US04634704,2,CC(=O)O.Fc1ccc(Cn2c(NC3CCN(CCNc4nccs4)CC3)nc3ccccc32)cc1>>CC(=O)N(CCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)CC1)c1nccs1 -US06008230,2,Nc1cccc2c(O)ccnc12.O=C(Cl)c1c(Cl)cccc1Cl>>Nc1cccc2c(OC(=O)c3c(Cl)cccc3Cl)ccnc12 -US09133224B2,1,CCOP(=O)(Cc1ccc(Nc2ncc(C(F)(F)F)c(Cl)n2)c(OC)c1Cl)OCC.CNC(=O)c1nc(Br)ccc1N>>CCOP(=O)(Cc1ccc(Nc2ncc(C(F)(F)F)c(Nc3ccc(Br)nc3C(=O)NC)n2)c(OC)c1Cl)OCC -US20110294781A1,1,C1COCCN1.Cc1ccc(-c2cc3nc(Cl)cc(Cl)n3n2)cc1>>Cc1ccc(-c2cc3nc(Cl)cc(N4CCOCC4)n3n2)cc1 -US20080188528A1,2,CC(c1ccccc1)n1cccc(C(=O)O)c1=O.Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(C(C)c3ccccc3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2 -US06441017B1,3,C[Mg+].N#Cc1ccc(C=O)cc1F>>CC(O)c1ccc(C#N)c(F)c1 -US07034045B1,2,CC(C)S(=O)(=O)NCC(C)(O)c1ccc(N)cc1.O=C(Cl)c1ccccc1>>CC(C)S(=O)(=O)NCC(C)(O)c1ccc(NC(=O)c2ccccc2)cc1 -US20110275797A1,6,COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(OCCN2CCN(CCCO)CC2)ccc1OCc1ccccc1>>COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(OCCN2CCN(CCCO)CC2)ccc1O -US05646171,6,CCCc1nc(C(C)(C)O)c(C(=O)OCC)[nH]1>>CCCc1nc(C(C)(C)O)c(C(=O)O)[nH]1 -US20070249670A1,2,COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1N)C(C)(C)C.O=C=Nc1c(Cl)cc(Cl)cc1Cl>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(Cl)cc(Cl)cc1Cl)C(C)(C)C -US20140066455A1,6,COc1cc(CCc2cc(NC(=O)c3cnc(N4CCC(N(C)C(=O)OC(C)(C)C)C4)cn3)[nH]n2)cc(OC)c1>>CNC1CCN(c2cnc(C(=O)Nc3cc(CCc4cc(OC)cc(OC)c4)n[nH]3)cn2)C1 -US20090298830A1,1,C1COCCN1.COc1cc([N+](=O)[O-])ccc1Cl>>COc1cc([N+](=O)[O-])ccc1N1CCOCC1 -US05162367,8,CC(O)CCCCCCOCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(=O)CCCCCCOCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US09139559B2,2,Cc1nc(OCC(=O)N(C)C2CCNCC2)nc(C)c1NC(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccccc1>>Cc1nc(OCC(=O)N(C)C2CCN(S(=O)(=O)c3ccccc3)CC2)nc(C)c1NC(=O)OC(C)(C)C -US20070249620A1,2,CC1CN(c2ccc(N)cc2)CCN1C(=O)OC(C)(C)C.COc1ccc(C)cc1N=C=O>>COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCN(C(=O)OC(C)(C)C)C(C)C2)cc1 -US20130252943A1,1,CCOC(=O)C(Cl)C(=O)CCNC(=O)OCc1ccccc1.O=C(O)COc1ccccc1>>CCOC(=O)C(OC(=O)COc1ccccc1)C(=O)CCNC(=O)OCc1ccccc1 -US05929097,3,COC(=O)c1cc(Br)cc(C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1.O=Cc1ccsc1B(O)O>>COC(=O)c1cc(-c2sccc2C=O)cc(C)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 -US07612075B2,1,CC(C)(C)OC(=O)n1c(CBr)cc2cc(Cl)ccc21.COC(=O)C1CNCC(=O)N1Cc1ccc(C#N)c(N=C(c2ccccc2)c2ccccc2)c1>>COC(=O)C1CN(Cc2cc3cc(Cl)ccc3n2C(=O)OC(C)(C)C)CC(=O)N1Cc1ccc(C#N)c(N=C(c2ccccc2)c2ccccc2)c1 -US07790745B2,1,CC(=O)Nc1cccc(CO)c1.COC(=O)[C@H]1c2ccc(O)cc2CCN1C(=O)OC(C)(C)C>>COC(=O)[C@H]1c2ccc(OCc3cccc(NC(C)=O)c3)cc2CCN1C(=O)OC(C)(C)C -US20130261133A1,3,C#C[C@@H](CCCCCCCCC)NCCCC.CCOc1ccc([C@H](O)C#CBr)cc1>>CCCCCCCCC[C@H](C#CC#C[C@@H](O)c1ccc(OCC)cc1)NCCCC -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.N#Cc1ccc(O)cc1>>CC#CCOc1cc(Oc2ccc(C#N)cc2)ncn1 -US20050137243A1,2,Nc1ccc2c(cnn2CCN2CCCC2)c1.O=C(O)Cc1ccc(Oc2ccccc2)cc1>>O=C(Cc1ccc(Oc2ccccc2)cc1)Nc1ccc2c(cnn2CCN2CCCC2)c1 -US06211199B1,2,COc1ccc(-n2cnnn2)cc1C(=O)N1CC[C@](CCO)(c2ccc(Cl)c(Cl)c2)C1.CS(=O)(=O)Cl>>COc1ccc(-n2cnnn2)cc1C(=O)N1CC[C@](CCOS(C)(=O)=O)(c2ccc(Cl)c(Cl)c2)C1 -US20120208994A1,2,O=C(Cl)c1ccccc1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OC(=O)c2ccccc2)cc1 -US20090163494A1,3,O=C1Cc2cc(F)ccc2N1.O=Cc1ccc(COCC(=O)O)[se]1>>O=C(O)COCc1ccc(/C=C2\C(=O)Nc3ccc(F)cc32)[se]1 -US06642389B2,10,C=CCc1nc(-c2ccc(OC)cc2)oc1C.O>>COc1ccc(-c2nc(CCCO)c(C)o2)cc1 -US04563474,1,CC(C#N)=CCCl.O=C1NS(=O)(=O)c2ccccc21>>CC(C#N)=CCN1C(=O)c2ccccc2S1(=O)=O -US08183262B2,3,CCCC[Sn](CCCC)(CCCC)c1cn(-c2cc(-c3ccc(C(F)(F)F)cc3)cc(C(F)(F)F)n2)cn1.Cc1nc(Cl)sc1S(=O)(=O)NC(C)(C)C>>Cc1nc(-c2cn(-c3cc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)cn2)sc1S(=O)(=O)NC(C)(C)C -US20070254882A1,6,COC(=O)CN(Cc1ccc(OCc2nc(-c3ccc(C)cc3)oc2C)cc1)S(=O)(=O)N1CCOCC1>>Cc1ccc(-c2nc(COc3ccc(CN(CC(=O)O)S(=O)(=O)N4CCOCC4)cc3)c(C)o2)cc1 -US20150065705A1,9,BrC(Br)(Br)Br.Cc1cc(CO)sc1Br>>Cc1cc(CBr)sc1Br -US20140206681A1,2,NCc1nccnc1Cl.O=C(O)[C@@H]1CC[C@@H]2CCCC(=O)N2C1>>O=C(NCc1nccnc1Cl)[C@@H]1CC[C@@H]2CCCC(=O)N2C1 -US08288419B2,3,CC1(c2cncc(Br)c2)OCCO1.CN(C)C=O>>CC1(c2cncc(C=O)c2)OCCO1 -US04181655,1,CN(C)CCCCl.FC(F)(F)OC1=Cc2ccccc2Nc2ccccc21>>CN(C)CCCN1c2ccccc2C=C(OC(F)(F)F)c2ccccc21 -US04005217,2,COC(=O)Cl.Nc1ccc(N)c([N+](=O)[O-])c1>>COC(=O)Nc1ccc(N)c([N+](=O)[O-])c1 -US04960792,5,CCCC[C@H]1CC(=O)CC[C@H]1C(=O)OCC.OCCO>>CCCC[C@@H]1CC2(CC[C@@H]1C(=O)OCC)OCCO2 -US20020156081A1,3,CC1(C)OB(c2ccc(Nc3nc4ccccc4o3)cc2)OC1(C)C.CN1CCN([C@@H]2CC[C@@H](n3nc(I)c4c(N)ncnc43)CC2)CC1>>CN1CCN([C@@H]2CC[C@@H](n3nc(-c4ccc(Nc5nc6ccccc6o5)cc4)c4c(N)ncnc43)CC2)CC1 -US08183262B2,3,Brc1cncc(Br)c1.Cc1cc(-c2ccc(Cl)cc2)cc(I)n1>>Cc1cc(-c2ccc(Cl)cc2)cc(-c2cncc(Br)c2)n1 -US20100234351A1,6,COC(=O)C1=Cc2c(OC)ncnc2N(Cc2ccc(OC)cc2)CCC1>>COC(=O)C1=Cc2c(ncnc2OC)NCCC1 -US04065471,7,O=C1CCCN1CC#CCN1CCCC1>>O=C1CCCN1CCCCN1CCCC1 -US20130023576A1,6,COC(=O)Cc1c(C)nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2F)c1C>>Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2F)c(C)c1CC(=O)O -US05849936,3,C=C[Mg+].CCCCCCCCCCC=O>>C=CC(O)CCCCCCCCCC -US08691187B2,3,CC1(C)OB(c2ccc(C#N)nc2)OC1(C)C.Clc1ccc2ccccc2n1>>N#Cc1ccc(-c2ccc3ccccc3n2)cn1 -US05039805,2,NCCC(=O)OCc1ccccc1.O=C(O)Cc1cccc([N+](=O)[O-])c1>>O=C(Cc1cccc([N+](=O)[O-])c1)NCCC(=O)OCc1ccccc1 -US20080306115A1,6,Cc1c(C(=O)Nc2ccc(C(F)(F)F)nc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1>>Cc1c(C(=O)Nc2ccc(C(F)(F)F)nc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1 -US20130040930A1,1,Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2C#N)CC1.O=S1(=O)CCCCN1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CCCCS3(=O)=O)cc2C#N)CC1 -US08093385B2,3,CCOC(=O)CCc1ccccc1OC(C(=O)OCC)C(C)CCCCCCOc1cc(Br)cc(-c2cn(C)c(=O)n(C)c2=O)c1.OB(O)c1ccccc1>>CCOC(=O)CCc1ccccc1OC(C(=O)OCC)C(C)CCCCCCOc1cc(-c2ccccc2)cc(-c2cn(C)c(=O)n(C)c2=O)c1 -US06538152B1,6,CCOC(=O)COc1ccc(CCN[C@@H](C)[C@H](O)c2ccc(O)cc2)cc1Br>>C[C@H](NCCc1ccc(OCC(=O)O)c(Br)c1)[C@H](O)c1ccc(O)cc1 -US08952169B2,2,CC1(COc2cc(F)c(C(=O)O)cc2C2CC2)CCC(F)(F)CC1.CNS(N)(=O)=O>>CNS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2(C)CCC(F)(F)CC2)cc1F -US06924292B2,6,COC(=O)c1ccc(Cn2ccc(C3=NC(C)(C)Cc4cc(OC)c5c(c43)CC(C)(C)O5)cc2=O)cc1>>COc1cc2c(c3c1OC(C)(C)C3)C(c1ccn(Cc3ccc(C(=O)O)cc3)c(=O)c1)=NC(C)(C)C2 -US20130131018A1,1,CCOC(CN)OCC.CCOc1cccc(C=O)c1O>>CCOc1cccc(CNCC(OCC)OCC)c1O -US20070191388A1,1,CCOC(=O)c1c(N2CCN(C(=O)c3cccs3)CC2)c2cc(Cl)cnc2[nH]c1=O.O=C(CBr)c1ccccc1>>CCOC(=O)c1c(N2CCN(C(=O)c3cccs3)CC2)c2cc(Cl)cnc2n(CC(=O)c2ccccc2)c1=O -US06037495,1,CC(=O)[O-].NC(=O)C(=O)c1ccccc1CCl>>CC(=O)OCc1ccccc1C(=O)C(N)=O -US20080293949A1,3,Cc1cc(C)cc(C=O)c1.O=C(O)Cc1ccc(O)cc1>>Cc1cc(C)cc(C=C(C(=O)O)c2ccc(O)cc2)c1 -US05856518,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1(C(N)C#N)CC1>>CCOC(=O)C1(C(C#N)NC(=O)OC(C)(C)C)CC1 -US05021435,1,CC1SC(c2cccnc2)NC1=O.CCOC(=O)CBr>>CCOC(=O)CN1C(=O)C(C)SC1c1cccnc1 -US04093812,9,NO.O=Cc1cn(-c2ccccc2)nc1-c1ccc([N+](=O)[O-])o1>>O=[N+]([O-])c1ccc(-c2nn(-c3ccccc3)cc2C=NO)o1 -US20080004252A1,4,N#CCN1C2CCC1CC(Oc1ccc(Cl)c(Cl)c1)C2.[N-]=[N+]=[N-]>>Clc1ccc(OC2CC3CCC(C2)N3Cc2nnn[nH]2)cc1Cl -US20090143354A1,1,CCOC(=O)CC1CCNCC1.O=C(NCC1CCCCC1)c1c(Cl)ccc2nc(Cl)ccc12>>CCOC(=O)CC1CCN(c2ccc3c(C(=O)NCC4CCCCC4)c(Cl)ccc3n2)CC1 -US20120316147A1,6,CC(C)(CC(=O)N1CCOCC1)NC(=O)OC(C)(C)C>>CC(C)(N)CC(=O)N1CCOCC1 -US06153641,1,BrCc1ccccc1CBr.Cn1cc(C2=C(c3c[nH]c4ccccc34)C(=O)OC2=O)c2ccccc21>>Cn1cc(C2=C(c3cn(Cc4ccccc4CBr)c4ccccc34)C(=O)OC2=O)c2ccccc21 -US20080305169A1,6,CC(C)(C)[Si](C)(C)OCCCOc1ccccc1NC(=O)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1>>O=C(Nc1ccccc1OCCCO)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1 -US04532349,9,O=C(CCl)Nc1ccc(S(=O)(=O)c2cccc(Cl)c2)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(=O)Nc1ccc(S(=O)(=O)c2cccc(Cl)c2)cc1 -US06528504B2,1,COc1cccc(CCOS(C)(=O)=O)c1.OC[C@H]1CCCCN1>>COc1cccc(CCN2CCCC[C@@H]2CO)c1 -US20150148332A1,3,C#C[Si](C)(C)C.COc1ccc(Cn2nc(Br)nc2N2CCCC2)cc1>>COc1ccc(Cn2nc(C#C[Si](C)(C)C)nc2N2CCCC2)cc1 -US20150210688A1,2,COC(=O)Cl.Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C2CNC2)nc1C>>COC(=O)N1CC(c2nc(C)c(-c3cc(C(=O)N4CC(c5ccc(C#N)cc5)C4)ccc3C)[nH]2)C1 -US20030083359A1,1,N[C@H]1CCCc2ccccc21.O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(CN[C@H]2CCCc3ccccc32)cc(C(F)(F)F)c1 -US20130158075A1,2,COC(=O)CCCc1nnc(-c2ccc(N)cc2)o1.Cc1cccc(N=C=O)c1>>COC(=O)CCCc1nnc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)o1 -US06610707B1,1,CC(N)=NOC(=O)[C@@H]1CCCCN1S(=O)(=O)c1ccc(F)cc1>>Cc1noc([C@@H]2CCCCN2S(=O)(=O)c2ccc(F)cc2)n1 -US08327467B2,1,CC(C)(C)OC(=O)c1ccc(CCc2ccccc2)cc1N.Clc1cccc(I)c1>>CC(C)(C)OC(=O)c1ccc(CCc2ccccc2)cc1Nc1cccc(Cl)c1 -US20050176785A1,1,CCOC(=O)CBr.Cc1cc(I)ccc1O>>CCOC(=O)COc1ccc(I)cc1C -US20100144786A1,4,CC(=O)C(Cc1ccc(C#N)cc1)C(=O)Nc1cc(O)ccc1Cl>>Cc1c(Cc2ccc(C#N)cc2)c(O)nc2c(Cl)ccc(O)c12 -US07491720B2,1,C1CCC(OC2CNCCNC2)OC1.C[Si](C)(C)CCOCn1ccc(Nc2cncc(CO)n2)n1>>C[Si](C)(C)CCOCn1ccc(Nc2cncc(CN3CCNCC(OC4CCCCO4)C3)n2)n1 -US20140315949A1,2,CC(C)(O)c1ccc(C(=O)O)cc1.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(C(C)(C)O)cc2)c(O)n1 -US07589232B2,6,CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(OCC(=O)OC)cc3)C(=O)c3cn[nH]c3)cc2)cc1>>CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(OCC(=O)O)cc3)C(=O)c3cn[nH]c3)cc2)cc1 -US20020183336A1,6,OC1(c2ccc3ccccc3c2)CC2CCC(C1)N2Cc1ccccc1>>OC1(c2ccc3ccccc3c2)CC2CCC(C1)N2 -US20110230493A1,2,Nc1cccnc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cccnc1)Oc1ccccc1 -US06727245B2,2,CN1CCNCC1.COc1ccccc1NC(=O)Nc1cccc(-n2c(=O)c(CCC(=O)O)nc3cccnc32)c1>>COc1ccccc1NC(=O)Nc1cccc(-n2c(=O)c(CCC(=O)N3CCN(C)CC3)nc3cccnc32)c1 -US05728835,2,CC(=O)OC(C)=O.Cc1cc(C)cc(N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)C(=O)c2ccc(N)cc2)c1>>CC(=O)Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c2cc(C)cc(C)c2)cc1 -US20080090854A1,6,COC(=O)C1(NC(=O)c2ccc3ccccc3c2OCC2COc3ccccc3O2)CCCC1>>O=C(NC1(C(=O)O)CCCC1)c1ccc2ccccc2c1OCC1COc2ccccc2O1 -US20090227530A1,6,C[C@@H]1OC[C@@H](O)[C@H](CN(CCOc2ccc(CCCCNC(=O)OCc3ccccc3)cc2)C[C@@H]2O[C@H](C)OC[C@H]2O)O1>>C[C@@H]1OC[C@@H](O)[C@H](CN(CCOc2ccc(CCCCN)cc2)C[C@@H]2O[C@H](C)OC[C@H]2O)O1 -US20120122842A1,7,O=C(Nc1ccc(C(=O)N(CCCN2CCOCC2)Cc2ccccc2)cc1)N1Cc2ccccc2C1>>O=C(Nc1ccc(CN(CCCN2CCOCC2)Cc2ccccc2)cc1)N1Cc2ccccc2C1 -US07749530B2,2,CC(=O)c1ccc(C(=O)O)s1.Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1>>CC(=O)c1ccc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4)c2)s1 -US08324396B2,1,CCC=O.NCCC(c1ccccc1)c1ccccc1>>CCCNCCC(c1ccccc1)c1ccccc1 -US04469634,7,CN1CCc2c(Cl)ccc([N+](=O)[O-])c2CC1>>CN1CCc2c(N)ccc(Cl)c2CC1 -US20150025073A1,6,COCC1CN(C(C)(C)C)CC2(CCN(C(=O)OC(C)(C)C)CC2)O1>>COCC1CN(C(C)(C)C)CC2(CCNCC2)O1 -US20050245563A1,7,CCOC(=O)CC(C)NC(=O)OC(C)(C)C>>CC(CCO)NC(=O)OC(C)(C)C -US20040097730A1,6,CCOC(=O)Cn1c(Cl)cnc(NCCCN(CC2CC2)C(=O)OC(C)(C)C)c1=O>>CC(C)(C)OC(=O)N(CCCNc1ncc(Cl)n(CC(=O)O)c1=O)CC1CC1 -US08372875B2,6,CC(C)C1CC2(CCS1)OCCO2>>CC(C)C1CC(=O)CCS1 -US20130109667A1,2,COc1ccc(CNc2ncns2)c(OC)c1.O=S(=O)(Cl)c1ccc(F)c(I)c1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(F)c(I)c2)c(OC)c1 -US07868205B2,2,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1N.N#Cc1ccc(CN2CCN(c3ncc(C(=O)O)s3)CC2)cc1>>CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)c1cnc(N2CCN(Cc3ccc(C#N)cc3)CC2)s1 -US05053408,1,ClCCCBr.O=C(O)c1ccccc1S>>O=C(O)c1ccccc1SCCCCl -US20040138462A1,6,Cc1nc(-c2ccc(S(=O)(=O)c3ccc(CCN(C[C@H](O)c4cccc(Cl)c4)C(=O)OC(C)(C)C)cc3)cc2)no1>>Cc1nc(-c2ccc(S(=O)(=O)c3ccc(CCNC[C@H](O)c4cccc(Cl)c4)cc3)cc2)no1 -US04423047,8,Clc1cnc(SCc2ccccc2)nc1.O=C(OO)c1cccc(Cl)c1>>O=S(Cc1ccccc1)c1ncc(Cl)cn1 -US20100010060A1,1,O=C(Nc1cccc2c1C(=O)NC2=O)c1ccc(Cl)s1.OCc1ccc(I)cc1>>O=C(Nc1cccc2c1C(=O)N(Cc1ccc(I)cc1)C2=O)c1ccc(Cl)s1 -US20120058988A1,9,COC(=O)c1cc(-c2cccc(Cl)c2)nc2c1[nH]c1nc(N3CCOCC3)ccc12.N>>NC(=O)c1cc(-c2cccc(Cl)c2)nc2c1[nH]c1nc(N3CCOCC3)ccc12 -US20130217759A1,2,CCc1sc(N)c(C(=O)OC)c1C.O=S(=O)(Cl)c1ccccc1>>CCc1sc(NS(=O)(=O)c2ccccc2)c(C(=O)OC)c1C -US20120107275A1,3,CCCC[Sn](CCCC)(CCCC)c1cc(C)no1.Fc1cc(Cl)cnc1F>>Cc1cc(-c2cnc(F)c(F)c2)on1 -US06177420B1,7,C[C@H](C=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](CO)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C -US20080132525A1,2,CC(C)(C)OC(=O)NCCN.CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12>>CN(C)c1cccc2c(S(=O)(=O)NCCNC(=O)OC(C)(C)C)cccc12 -US20090186895A1,1,Cn1nccc1-c1cc(NC(=O)c2ccc(F)cc2F)ccc1OCCBr.NC1CCOCC1>>Cn1nccc1-c1cc(NC(=O)c2ccc(F)cc2F)ccc1OCCNC1CCOCC1 -US06194396B1,1,CCOC(=O)CBr.COc1cccc(C=O)c1O>>CCOC(=O)COc1c(C=O)cccc1OC -US20080275032A1,2,COC(=O)CC(=O)Cl.CS(=O)(=O)Nc1ccc(N)c(S(N)(=O)=O)c1>>COC(=O)CC(=O)Nc1ccc(NS(C)(=O)=O)cc1S(N)(=O)=O -US04536391,2,CS(=O)(=O)Cl.N#Cc1ccc(CCCO)cc1>>CS(=O)(=O)OCCCc1ccc(C#N)cc1 -US06211234B1,1,COC(=O)c1ccc(OCc2ccsc2)cc1O.C[Si](C)(C)CCOCCl>>COC(=O)c1ccc(OCc2ccsc2)cc1OCOCC[Si](C)(C)C -US20070265265A1,3,Nc1nc(Br)cs1.OB(O)c1ccco1>>Nc1nc(-c2ccco2)cs1 -US06329381B1,1,CC(C)S.Nc1nc(Cl)nc2c1ncn2Cc1ccccc1>>CC(C)Sc1nc(N)c2ncn(Cc3ccccc3)c2n1 -US05464607,1,C1=COCCC1.O=C(CCl)NCC(O)CNC(=O)CCl>>O=C(CCl)NCC(CNC(=O)CCl)OC1CCCCO1 -US07199239B2,1,CCOC(=O)COc1ccc(CBr)cc1C.COCCNc1cccc(-c2ccc(C(F)(F)F)cc2)c1>>CCOC(=O)COc1ccc(CN(CCOC)c2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1C -US08691187B2,3,CC(=O)c1ccc(Br)cc1.CC1(C)OB(c2ccc(F)nc2)OC1(C)C>>CC(=O)c1ccc(-c2ccc(F)nc2)cc1 -US20040009956A1,6,COC(=O)c1ccc(C=CC=O)cc1>>O=CC=Cc1ccc(C(=O)O)cc1 -US20120115869A1,1,CS(=O)(=O)c1ccc(C=O)cc1.N#Cc1cc(N)cc(F)c1>>CS(=O)(=O)c1ccc(CNc2cc(F)cc(C#N)c2)cc1 -US20120329775A1,9,CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(-c3cccc(C#N)c3)cc2)C(N)=O)CCOCC1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@H](C#N)Cc2ccc(-c3cccc(C#N)c3)cc2)CCOCC1 -US20050148627A1,3,C#Cc1cccnc1.CCOC(=O)C1=Cc2cc(OC(F)(F)F)cc(I)c2OC1C(F)(F)F>>CCOC(=O)C1=Cc2cc(OC(F)(F)F)cc(C#Cc3cccnc3)c2OC1C(F)(F)F -US08642629B2,7,C#Cc1c(CC(=O)OC)cc2ccc(F)cc2c1OC(C)=O>>CCc1c(CC(=O)OC)cc2ccc(F)cc2c1OC(C)=O -US08426429B2,6,COC(OC)c1cc(Oc2cccc(NC(=O)OCc3ccccc3)c2)ccc1[N+](=O)[O-]>>O=Cc1cc(Oc2cccc(NC(=O)OCc3ccccc3)c2)ccc1[N+](=O)[O-] -US20150150879A2,2,CC(C)(C)c1cc2cc(N)ccc2[nH]1.COc1ccc(C2(C(=O)O)CC2)cc1>>COc1ccc(C2(C(=O)Nc3ccc4[nH]c(C(C)(C)C)cc4c3)CC2)cc1 -US20070197604A1,1,CCOC(=O)Cc1coc(-c2ccc(O)cc2)n1.ClCc1cscn1>>CCOC(=O)Cc1coc(-c2ccc(OCc3cscn3)cc2)n1 -US07414061B2,1,Cc1onc(-c2ccccc2)c1-c1c[nH]cn1.Fc1ccccn1>>Cc1onc(-c2ccccc2)c1-c1cn(-c2ccccn2)cn1 -US06180316B2,3,C1=CCC=C1.CC(C)(C)OC(=O)C1CC2C=CC1C2>>CC(C)(C)OC(=O)C1CC2CC1C1C3C=CC(C3)C21 -US20040102437A1,2,Nc1ccncc1.O=C=Nc1c(F)cccc1F>>O=C(Nc1ccncc1)Nc1c(F)cccc1F -US20090275592A1,6,CC(C)(C)OC(=O)N[C@H](CCc1nnc(-c2ccc3cnccc3c2)o1)Cc1ccc(C(F)(F)F)cc1>>N[C@H](CCc1nnc(-c2ccc3cnccc3c2)o1)Cc1ccc(C(F)(F)F)cc1 -US20110237581A1,1,CCOC(OCC)c1ccc(C=O)cc1.Nc1cccc2c1COC2=O>>CCOC(OCC)c1ccc(C=Nc2cccc3c2COC3=O)cc1 -US05624950,3,COc1ccccc1[Mg+].O=C1CCCC2CN(Cc3ccccc3)CC12>>COc1ccccc1C1(O)CCCC2CN(Cc3ccccc3)CC21 -US20110028509A1,1,O=C(NCC1CC1)c1ccc(CBr)cc1.O=S(=O)(NCc1ccccn1)c1ccc(Cl)cc1>>O=C(NCC1CC1)c1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US03946045,1,Cc1cccc(C)c1N.ClCC1COCO1>>Cc1cccc(C)c1NCC1COCO1 -US20140088081A1,6,c1ccc(C2CN(C(c3ccccc3)c3ccccc3)C2)cc1>>c1ccc(C2CNC2)cc1 -US07220766B2,6,COC(=O)C(Cc1ccc(OCc2ccccc2)cc1)SC1=NS(=O)(=O)c2ccccc21>>O=C(O)C(Cc1ccc(OCc2ccccc2)cc1)SC1=NS(=O)(=O)c2ccccc21 -US20020173526A1,1,ICCCCc1ccc(OCc2ccccc2)cc1.c1c[nH]nn1>>c1ccc(COc2ccc(CCCCn3ccnn3)cc2)cc1 -US20060281755A1,2,CC(C)c1ccc(CC(=O)O)cc1.CON=Cc1c(N)ncnc1N1CCNCC1>>CON=Cc1c(N)ncnc1N1CCN(C(=O)Cc2ccc(C(C)C)cc2)CC1 -US08273900B2,1,Cc1cncc(N)c1.O=C[C@@H]1CC[C@@H](NC(=O)c2cc(C(F)(F)F)ccc2Cl)CC1>>Cc1cncc(NC[C@@H]2CC[C@@H](NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)c1 -US08124600B2,1,CN1C2CCC1CC(N)C2.COC(=O)c1cccc2c1c(C=O)nn2C>>COC(=O)c1cccc2c1c(CNC1CC3CCC(C1)N3C)nn2C -US20150104384A1,2,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1 -US04772600,2,CCCNCCC.O=C(O)Cn1c(-c2ccc(Cl)c(Cl)c2)nc2cccnc21>>CCCN(CCC)C(=O)Cn1c(-c2ccc(Cl)c(Cl)c2)nc2cccnc21 -US04772600,2,O=C(O)Cn1c(-c2ccc(Cl)c(Cl)c2)nc2cccnc21>>O -US20100069351A1,7,C1=CC2(CCNC2)Oc2ccccc21>>c1ccc2c(c1)CCC1(CCNC1)O2 -US20090203753A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCNCCCOCCc1ccccc1>>CC(C)(C)OC(=O)N(CCO)CCCOCCc1ccccc1 -US20080269523A1,2,CC(=O)OC(C)=O.CC1(C)OB(c2cccc(N)c2)OC1(C)C>>CC(=O)Nc1cccc(B2OC(C)(C)C(C)(C)O2)c1 -US20140213581A1,1,COC(=O)c1cnc(Cl)cn1.OCC(F)(F)F>>COC(=O)c1cnc(OCC(F)(F)F)cn1 -US20100331306A1,1,CC(C)NC(=O)c1c(-c2ccccc2)c(C(C)N)nc2ccc(F)cc12.N#Cc1c(N)ncnc1Cl>>CC(C)NC(=O)c1c(-c2ccccc2)c(C(C)Nc2ncnc(N)c2C#N)nc2ccc(F)cc12 -US08853215B2,2,CC(C)(C)c1ccccc1N1CCNCC1.O=C(O)C12CC3CC(C1)CC(C(=O)O)(C3)C2>>CC(C)(C)c1ccccc1N1CCN(C(=O)C23CC4CC(CC(C(=O)O)(C4)C2)C3)CC1 -US20070010526A1,2,C1CCNC1.O=C(O)Cc1ccc(S(=O)(=O)Cl)cc1>>O=C(O)Cc1ccc(S(=O)(=O)N2CCCC2)cc1 -US06169090A,6,COc1ncc(Br)c2cc(C3(OC)CCN(C(=O)OC(C)(C)C)CC3)oc12>>COc1ncc(Br)c2cc(C3(OC)CCNCC3)oc12 -US07094798B1,1,CNC.CS(=O)(=O)OCCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4)cc21)C(=O)NC3=O>>CN(C)CCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4)cc21)C(=O)NC3=O -US08735435B2,1,CI.Clc1nc(Br)[nH]c1Cl>>Cn1c(Br)nc(Cl)c1Cl -US05194440,7,CCOC(=O)c1ccc2[nH]cc(CCNC(=O)OC(C)(C)C)c2c1>>CC(C)(C)OC(=O)NCCc1c[nH]c2ccc(CO)cc12 -US08796335B2,7,COC(=O)CC(C)(c1ccc(Cl)c([N+](=O)[O-])c1)C1CCC1>>COC(=O)CC(C)(c1ccc(Cl)c(N)c1)C1CCC1 -US07560558B2,3,COc1cc2nccc(Oc3ccc(C)nc3I)c2cc1OC.Cc1ccc(B(O)O)cc1>>COc1cc2nccc(Oc3ccc(C)nc3-c3ccc(C)cc3)c2cc1OC -US05760246,2,NCc1ccccc1.O=C(O)C1c2ccccc2-c2ccccc21>>O=C(NCc1ccccc1)C1c2ccccc2-c2ccccc21 -US20090012081A1,3,CC(C)c1ccccc1.CCC(=O)Cl>>CCC(=O)c1ccc(C(C)C)cc1 -US05834463,7,O=C1[C@H]2CCC[C@H]2Nc2ccccc2N1Cc1ccc([N+](=O)[O-])cc1>>Nc1ccc(CN2C(=O)[C@H]3CCC[C@H]3Nc3ccccc32)cc1 -US05374744,7,CCCCCCCC/C=C\[C@H]1C=CC(=O)O1>>CCCCCCCC/C=C\[C@H]1CCC(=O)O1 -US20140128613A1,3,COc1cc2c(cc1OC)C(=O)CC2.O=Cc1ccncc1>>COc1cc2c(cc1OC)C(=O)C(=Cc1ccncc1)C2 -US20150266837A1,1,CN(C)CCCNN.COc1ccc(Cn2nnnc2Br)cc1>>COc1ccc(Cn2nnnc2N(N)CCCN(C)C)cc1 -US09115152B2,7,C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3cccc(-n4ncc5c6c(sc5c4=O)CCCC6)c3C=O)cn(C)c2=O)nc1>>C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3cccc(-n4ncc5c6c(sc5c4=O)CCCC6)c3CO)cn(C)c2=O)nc1 -US20020173664A1,2,C[C@@H]1NC(=O)OC1=O.O=C(Cl)c1ccccc1>>C[C@H]1C(=O)OC(=O)N1C(=O)c1ccccc1 -US20150119381A1,6,Cc1cc(-c2ccc3c(c2)CC[C@H]3N2CC3(CCN(C(=O)OC(C)(C)C)CC3)C2)ncn1>>Cc1cc(-c2ccc3c(c2)CC[C@H]3N2CC3(CCNCC3)C2)ncn1 -US07582773B2,6,CCCCCc1c(-c2ccccc2)n(Cc2ccccc2)c2ccc(-c3ccc(OC)cc3)cc12>>CCCCCc1c(-c2ccccc2)n(Cc2ccccc2)c2ccc(-c3ccc(O)cc3)cc12 -US20080153873A1,1,CC1(C)C(=O)N(C(c2ccccc2F)C(O)CO)c2ccccc21>>CC1(C)C(=O)N(C2c3ccccc3OC2CO)c2ccccc21 -US20100075978A1,2,C1CCN(CCCN2CCNCC2)CC1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccccc2)cc1>>O=C(c1ccccc1)c1ccccc1NS(=O)(=O)c1ccc(C(=O)N2CCN(CCCN3CCCCC3)CC2)cc1 -US20110059948A1,6,COC(=O)C(C(=O)OC)C(c1ccccc1)c1cc2cc(Br)ccc2nc1OC>>COC(=O)C(C(=O)O)C(c1ccccc1)c1cc2cc(Br)ccc2nc1OC -US07994331B2,5,COCCl.Oc1ccc(Br)nc1>>COCOc1ccc(Br)nc1 -US08835472B2,1,CCCO.Clc1cc(I)ccn1>>CCCOc1cc(I)ccn1 -US20090149475A1,1,CC(C)(C)OC(=O)n1cc(C=O)c2cc(F)ccc21.NC(=O)c1[nH]cnc1N>>CC(C)(C)OC(=O)n1cc(CNc2nc[nH]c2C(N)=O)c2cc(F)ccc21 -US20130261101A1,1,Cc1nn(C(C)c2cc(Cl)c(C#N)c3c2OCCNC3)c2ncnc(N)c12.OCCBr>>Cc1nn(C(C)c2cc(Cl)c(C#N)c3c2OCCN(CCO)C3)c2ncnc(N)c12 -US20100160369A1,6,Cc1c(I)ccc2nc(-c3nc(-c4cc(F)c(CCC(=O)OC(C)(C)C)cc4Cl)no3)cn12>>Cc1c(I)ccc2nc(-c3nc(-c4cc(F)c(CCC(=O)O)cc4Cl)no3)cn12 -US03932432,1,BrCC1CC1.CC(CCCc1ccc(F)cc1)C1=CC(O)(O)C2=C3CNCCC3C(C)(C)OC2=C1>>CC(CCCc1ccc(F)cc1)C1=CC(O)(O)C2=C3CN(CC4CC4)CCC3C(C)(C)OC2=C1 -US04973699,5,Nc1nc(C(=NOC2CC2)C(=O)O)cs1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)C(=NOC1CC1)c1csc(NC(=O)C(F)(F)F)n1 -US20150105366A1,8,COc1nc2ccc(C(O)c3cncn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1>>COc1nc2ccc(C(=O)c3cncn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 -US20070249670A1,6,CC(C)(C)OC(=O)c1cc(Br)sc1NC(=O)C(F)(F)F>>CC(C)(C)OC(=O)c1cc(Br)sc1N -US20140179733A1,2,CC(C)Oc1c(N)cnn1-c1ccc(F)cc1.Cc1nc(C(F)(F)F)cn1C(C)C(=O)O>>Cc1nc(C(F)(F)F)cn1C(C)C(=O)Nc1cnn(-c2ccc(F)cc2)c1OC(C)C -US09018214B2,1,C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](CCl)CN1C(=O)OC(C)(C)C.O=c1nccc[nH]1>>C[C@@H]1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)[C@@H](Cn2cccnc2=O)CN1C(=O)OC(C)(C)C -US20130178459A1,1,CC(C)(C)OC(=O)NC1CCNCC1.CC1(C)OB(/C=C\CCl)OC1(C)C>>CC(C)(C)OC(=O)NC1CCN(C/C=C/B2OC(C)(C)C(C)(C)O2)CC1 -US06313310B1,3,C#CC(O)c1ccc(OC)c(O)c1.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1ccc(C(O)C#Cc2cccc3c2/C(=C/c2[nH]ccc2OC)C(=O)N3)cc1O -US20090054508A1,2,Cc1ccsc1C(=O)O.Nc1cc(N2CCOCC2)ccc1/C=C/c1n[nH]c2ccccc12>>Cc1ccsc1C(=O)Nc1cc(N2CCOCC2)ccc1/C=C/c1n[nH]c2ccccc12 -US20120309739A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4nc(N5CCNCC5)ncc4c3-c3ccccc3)cc2)CCC1>>NC1(c2ccc(-c3oc4nc(N5CCNCC5)ncc4c3-c3ccccc3)cc2)CCC1 -US20050272778A1,6,COC(=O)Cc1ccc(-c2cc(=O)n(C(C)(C)C)s2)cc1>>CC(C)(C)n1sc(-c2ccc(CC(=O)O)cc2)cc1=O -US20130045962A1,2,C[C@@H]1CN(C)CCN1c1nc(Cl)nc(NN)c1F.O=CN(C[C@@H](CC1CCCC1)C(=O)O)OCc1ccccc1>>C[C@@H]1CN(C)CCN1c1nc(Cl)nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c1F -US20110275797A1,7,CC(=O)Oc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)OC(C)(C)C)c(OCc2ccccc2)c1>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(O)cc1OCc1ccccc1 -US20080306115A1,2,Cc1c(C(=O)O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1.Nc1ccc(C(F)(F)F)nc1>>Cc1c(C(=O)Nc2ccc(C(F)(F)F)nc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1 -US20100041892A1,2,CC(C)c1cc(CCC(=O)O)n(Cc2ccc(C(F)(F)F)cc2Cl)n1.CCCCCS(N)(=O)=O>>CCCCCS(=O)(=O)NC(=O)CCc1cc(C(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl -US06528504B2,6,CC(C)(C)OC(=O)N1CC[C@H](OC(=O)c2ccc([N+](=O)[O-])cc2)C1>>O=C(O[C@H]1CCNC1)c1ccc([N+](=O)[O-])cc1 -US20090018116A1,2,Nc1ccc(Cl)cc1C(=O)NCC1CCCCC1.O=C(Cl)c1cccc(F)c1F>>O=C(NCC1CCCCC1)c1cc(Cl)ccc1NC(=O)c1cccc(F)c1F -US07183306B2,7,C=C(C)c1cc(-c2ccc(OCCNC(=O)OC(C)(C)C)cc2)n(-c2ccc(OC)cc2)n1>>COc1ccc(-n2nc(C(C)C)cc2-c2ccc(OCCNC(=O)OC(C)(C)C)cc2)cc1 -US05705499,7,CCN1c2ncc(/C=C/c3ccncc3)cc2C(=O)N(C)c2cccnc21>>CCN1c2ncc(CCc3ccncc3)cc2C(=O)N(C)c2cccnc21 -US20100137445A1,2,NCC1CCCCC1.O=C(Cl)c1ccc(F)c(F)c1>>O=C(NCC1CCCCC1)c1ccc(F)c(F)c1 -US08101747B2,1,C=O.COc1cc2c(cc1OC)CC(=O)N(CCCNC[C@H]1Cc3cc(OC)c(OC)cc31)CC2>>COc1cc2c(cc1OC)CC(=O)N(CCCN(C)C[C@H]1Cc3cc(OC)c(OC)cc31)CC2 -US20150152112A1,1,FC(F)(F)c1cn[nH]c1.Fc1ccc(Cl)cc1Br>>FC(F)(F)c1cnn(-c2ccc(Cl)cc2Br)c1 -US20060063784A1,2,Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1.O=C(O)c1ccncc1>>O=C(Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1)c1ccncc1 -US03974141,2,CCS(=O)(=O)N1CCNC1=O.O=C(Cl)Cl>>CCS(=O)(=O)N1CCN(C(=O)Cl)C1=O -US20090156642A1,1,O=Cc1cc(Br)c(-c2ccccc2F)o1.Sc1ccccc1>>O=Cc1cc(Sc2ccccc2)c(-c2ccccc2F)o1 -US06869947B2,1,Cn1c(=O)[nH]c(=O)c2[nH]c(Br)nc21.FC(F)(F)c1ccccc1CBr>>Cn1c(=O)[nH]c(=O)c2c1nc(Br)n2Cc1ccccc1C(F)(F)F -US20110130406A1,1,C=O.COc1ccc(Cn2nc(O[C@H]3CCCNC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(O[C@H]3CCCN(C)C3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1 -US20110263571A1,1,C[C@@H]1COC(=O)N1.Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3NS(C)(=O)=O)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)cc3NS(C)(=O)=O)CC2)c(C)c1 -US04154840,2,CC(CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O.O=C(O)[C@@H]1CCCN1>>CC(CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)O -US06051572,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NCCN(C2CCNCC2)C1c1ccccc1>>CC(C)(C)OC(=O)N1CCC(N2CCNC(=O)C2c2ccccc2)CC1 -US05021569,1,O=C(CCBr)N1CC2CC3CC(C2)CC1C3.c1cnc(N2CCNCC2)nc1>>O=C(CCN1CCN(c2ncccn2)CC1)N1CC2CC3CC(C2)CC1C3 -US20150080287A1,4,C=CCc1cccc(C)c1C.OO>>Cc1cccc(CC2CO2)c1C -US20110319385A1,6,CC(=O)OC(C(=O)OCc1ccccc1)C1CC1>>CC(=O)OC(C(=O)O)C1CC1 -US04221815,9,O=C(O)c1ccccc1O>>O=C(O)c1ccccc1 -US20070191376A1,3,Brc1cnc2c(OCc3ccccc3)cccn12.C#C[Si](C)(C)C>>C[Si](C)(C)C#Cc1cnc2c(OCc3ccccc3)cccn12 -US20090105212A1,1,CCCCOc1nc(N)c2nc(OC)n(Cc3ccc(OCCCCCl)cc3)c2n1.CCOC(=O)C1CCNCC1>>CCCCOc1nc(N)c2nc(OC)n(Cc3ccc(OCCCCN4CCC(C(=O)OCC)CC4)cc3)c2n1 -US20060211739A1,9,CN(C)Cc1ccsc1CN=[N+]=[N-]>>CN(C)Cc1ccsc1CN -US20090275564A1,1,NC1CCCC1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>O=[N+]([O-])c1cnc(Cl)nc1NC1CCCC1 -US05726195,4,C[Si](C)(C)N=[N+]=[N-].N#Cc1ccc(Oc2ccccc2)cc1>>c1ccc(Oc2ccc(-c3nnn[nH]3)cc2)cc1 -US05532241,6,COc1ccc2[nH]cc(CCCCN3CCN(c4ccc5c(c4)CCCO5)CC3)c2c1>>Oc1ccc2[nH]cc(CCCCN3CCN(c4ccc5c(c4)CCCO5)CC3)c2c1 -US06969725B2,1,CCO[C@@H](Cc1ccc(O)cc1C)C(=O)OC.Cc1oc(-c2ccccc2F)nc1CCl>>CCO[C@@H](Cc1ccc(OCc2nc(-c3ccccc3F)oc2C)cc1C)C(=O)OC -US08088815B2,6,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2)c(OC)c1>>COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1 -US20100261772A1,1,O=C(c1ccccc1)c1ccc(O)cc1.OCCCl>>O=C(c1ccccc1)c1ccc(OCCO)cc1 -US05051417,3,CC1SC(=O)NN=C1c1ccc2c(c1)CC(=O)N2.O=Cc1cccnc1>>CC1SC(=O)NN=C1c1ccc2c(c1)C(=Cc1cccnc1)C(=O)N2 -US20110152246A1,6,COc1ccc(-c2ccc(Br)c3ccccc23)cc1>>Oc1ccc(-c2ccc(Br)c3ccccc23)cc1 -US20050228017A1,2,CC(C)C(=O)Cl.COc1cc(CNCCC(=O)NOC(C)(C)C)ccc1OCc1ccccc1>>COc1cc(CN(CCC(=O)NOC(C)(C)C)C(=O)C(C)C)ccc1OCc1ccccc1 -US05411989,2,N[C@@H]1CC[C@@H](O[N+](=O)[O-])CC1.O=CO>>O=CN[C@@H]1CC[C@@H](O[N+](=O)[O-])CC1 -US06890947B2,7,CCOC(=O)/C(=C/c1ccc2[nH]ccc2c1)OCC>>CCOC(=O)C(Cc1ccc2[nH]ccc2c1)OCC -US06277859B1,1,C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5.CN>>C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](NC)CC[C@@]3(O)[C@H]1C5 -US06277859B1,1,C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5.CN>>C=CCN1CC[C@]23c4c5ccc(O)c4O[C@@H]2C(NC)CC[C@@]3(O)[C@H]1C5 -US20110130415A1,7,Cc1ccc([N+](=O)[O-])cc1-n1nnn(C)c1=O>>Cc1ccc(N)cc1-n1nnn(C)c1=O -US20080234199A1,3,C=CC(=O)OCC.CCCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(Br)cc1>>CCCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(/C=C/C(=O)OCC)cc1 -US20090048258A1,1,CCOc1ccc(C(=O)CCC(=O)Nc2cc(-c3ccc(O)cc3)c3ccccc3n2)cc1OCC.ClCCN1CCOCC1>>CCOc1ccc(C(=O)CCC(=O)Nc2cc(-c3ccc(OCCN4CCOCC4)cc3)c3ccccc3n2)cc1OCC -US07592477B2,6,CCCCCCCCCCCCNC(=O)c1ccc(CN(CC2CCN(C(=O)OC(C)(C)C)CC2)C(=O)C(=O)OCC)cc1>>CCCCCCCCCCCCNC(=O)c1ccc(CN(CC2CCNCC2)C(=O)C(=O)OCC)cc1 -US20120172392A1,10,C=C(C)CN1C(=O)c2ccccc2C1=O.O=C1CCC(=O)N1Br>>C=C(CBr)CN1C(=O)c2ccccc2C1=O -US20080021026A1,6,COc1cccc(Sc2ccc3sc(-c4ccnc(N)n4)c(C)c3c2)c1>>Cc1c(-c2ccnc(N)n2)sc2ccc(Sc3cccc(O)c3)cc12 -US20150038574A1,1,CC1=C(CO)C(C)(C)CCC1.Oc1ccc(F)c(F)c1>>CC1=C(COc2ccc(F)c(F)c2)C(C)(C)CCC1 -US20130096084A1,1,CC(C)(C)OC(=O)N[C@H]1CCCNC1.O=Cc1ccccc1>>CC(C)(C)OC(=O)N[C@H]1CCCN(Cc2ccccc2)C1 -US07553867B2,7,COC(=O)C(C)(C)Cc1ccc(OCc2oc(-c3ccc(C(F)(F)F)cc3)cc2C(=O)O)cc1>>COC(=O)C(C)(C)Cc1ccc(OCc2oc(-c3ccc(C(F)(F)F)cc3)cc2CO)cc1 -US04272507,6,COC(=O)c1scc(C)c1Nc1c(Cl)cccc1Cl>>Cc1csc(C(=O)O)c1Nc1c(Cl)cccc1Cl -US08440651B2,2,CC(=O)O.Clc1nc(N2CCOCC2)c2nc(CC3CCNCC3)ccc2n1>>CC(=O)N1CCC(Cc2ccc3nc(Cl)nc(N4CCOCC4)c3n2)CC1 -US20150284396A1,1,CC1CNC1.CCCCc1nc(N)c2c(n1)c(C#CCCC=O)cn2COCc1ccccc1>>CCCCc1nc(N)c2c(n1)c(C#CCCCN1CC(C)C1)cn2COCc1ccccc1 -US06987114B1,1,CCc1c(C(=O)c2cc(C)cc(C)c2)[nH]c(=O)[nH]c1=O.ClCc1ccccn1>>CCc1c(C(=O)c2cc(C)cc(C)c2)n(Cc2ccccn2)c(=O)[nH]c1=O -US08916557B2,1,CC(C)CCCO.CS(=O)(=O)Cc1cccc(Nc2ncnc(-c3ccc(F)cc3F)n2)c1>>CC(C)CCCOc1cc(F)ccc1-c1ncnc(Nc2cccc(CS(C)(=O)=O)c2)n1 -US05364871,1,N#Cc1cccc(CCl)n1.O=C1NC(=O)c2ccccc21>>N#Cc1cccc(CN2C(=O)c3ccccc3C2=O)n1 -US07727997B2,6,CCCCN(Cc1cc(C)cc(C(=O)OC)c1)C(=O)OC(C)(C)C>>CCCCN(Cc1cc(C)cc(C(=O)O)c1)C(=O)OC(C)(C)C -US06022492,1,CCCCCCBr.CCCCCCCCOc1ccc(-c2cnc(-c3ccc(O)c(F)c3F)nc2)cn1>>CCCCCCCCOc1ccc(-c2cnc(-c3ccc(OCCCCCC)c(F)c3F)nc2)cn1 -US20070167452A1,1,OC[C@H]1CC[C@@H](CN(Cc2ccccc2)Cc2ccccc2)CC1.Oc1ccccc1>>c1ccc(CN(Cc2ccccc2)C[C@@H]2CC[C@H](COc3ccccc3)CC2)cc1 -US08309550B2,1,CCCI.c1cc2cc[nH]c2cn1>>CCCn1ccc2ccncc21 -US20030083359A1,1,O=Cc1cccc(O)c1.O=[N+]([O-])c1ccc(F)cc1>>O=Cc1cccc(Oc2ccc([N+](=O)[O-])cc2)c1 -US08598154B2,1,BrCC1CCC1.COc1ccc(S(=O)(=O)N2CCC3=Cc4c(cnn4-c4ccc(F)cc4)C[C@]3(C(=O)O)C2)cn1>>COc1ccc(S(=O)(=O)N2CCC3=Cc4c(cnn4-c4ccc(F)cc4)C[C@]3(C(=O)OCC3CCC3)C2)cn1 -US20130184313A1,6,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc([C@@H]2C[C@H]2CCF)c1>>FCC[C@@H]1C[C@H]1c1cncc(OC[C@@H]2CCN2)c1 -US20060211739A1,1,BrCc1cccnc1.Clc1ccc(-c2nnn[nH]2)c(Cl)c1Cl>>Clc1ccc(-c2nnnn2Cc2cccnc2)c(Cl)c1Cl -US08759348B2,6,Cc1cc(N2CCC(c3ccccc3)C2)c2cc(OCc3ccccc3)ccc2n1>>Cc1cc(N2CCC(c3ccccc3)C2)c2cc(O)ccc2n1 -US20070142371A1,4,C#Cc1ccc(CN2CCOCC2)nc1.Cc1ccc(C(=O)O)cc1N=[N+]=[N-]>>Cc1ccc(C(=O)O)cc1-n1cc(-c2ccc(CN3CCOCC3)nc2)nn1 -US06143198,6,COCC1CCC(c2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)CC1>>OCC1CCC(c2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)CC1 -US20100210642A1,3,C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12.O=S(=O)(Nc1cccnc1)c1ccc(Br)s1>>O=S(=O)(Nc1cccnc1)c1ccc(C#Cc2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)s1 -US05380739,6,CC(C)(C)OC(=O)c1ccc(-n2c(C#N)cc3ccccc32)cc1>>N#Cc1cc2ccccc2n1-c1ccc(C(=O)O)cc1 -US20100081670A1,1,Cc1cc(CO)no1.Cc1cnc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(Br)n1>>Cc1cnc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(OCc2cc(C)on2)n1 -US20110118261A1,1,Brc1ccc(N2CCC(NC3CCCC3)C2)nc1.O=c1cc(OCc2ccc(Cl)cn2)cc[nH]1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(N2CCC(NC3CCCC3)C2)nc1 -US04322546,3,C#CC[Mg+].C=C=CC(=O)CCCC>>C#CCC(O)(C=C=C)CCCC -US20100056527A1,4,CCOC(=O)C(=O)CC(C)=O.NNCc1cc(Cl)cc(Br)c1O>>CCOC(=O)c1cc(C)n(Cc2cc(Cl)cc(Br)c2O)n1 -US20150210686A1,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=c1[nH]c(-c2ccc(Br)cc2)cc2cnccc12>>Cn1cc(-c2ccc(-c3cc4cnccc4c(=O)[nH]3)cc2)cn1 -US06204406B1,2,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O -US20150141400A1,2,CCSc1ccc(Cl)cc1CN.Nc1c(Cl)cc(OC(F)(F)F)cc1C(=O)O>>CCSc1ccc(Cl)cc1CNC(=O)c1cc(OC(F)(F)F)cc(Cl)c1N -US08178699B2,4,BrCCCCBr.Cc1ccccc1N>>Cc1ccccc1N1CCCC1 -US20100179168A1,7,Cc1ccc(-c2ccc(S(=O)(=O)Nc3cccc([N+](=O)[O-])c3)cc2F)o1>>Cc1ccc(-c2ccc(S(=O)(=O)Nc3cccc(N)c3)cc2F)o1 -US20140005175A1,2,CC(C)(C(=O)O)c1cccc(S(=O)(=O)/C=C/C#N)c1.COc1cccc(N)c1>>COc1cccc(NC(=O)C(C)(C)c2cccc(S(=O)(=O)/C=C/C#N)c2)c1 -US06432993B1,2,Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(N)cc3)cc21.O=C(Cl)c1cccnc1>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(NC(=O)c4cccnc4)cc3)cc21 -US08912200B2,3,C#Cc1ccc(C(=O)N2CCN(C)CC2)cc1.Cc1ccc(Cl)cc1-c1c(C(N)=O)cc(-c2nc(N)ncc2I)n1COCC[Si](C)(C)C>>Cc1ccc(Cl)cc1-c1c(C(N)=O)cc(-c2nc(N)ncc2C#Cc2ccc(C(=O)N3CCN(C)CC3)cc2)n1COCC[Si](C)(C)C -US20110105470A1,2,O=C(Cl)c1cccc(Cl)c1.O=C1C(=O)c2ccc(-c3ccccc3)cc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccc(-c3ccccc3)cc2C2=C1SCC1(CCN(C(=O)c3cccc(Cl)c3)CC1)O2 -US20110065789A1,2,C=CCc1c(F)c(F)c(CO)c(F)c1F.CC(C#N)=C[C@@H]1[C@@H](C(=O)O)C1(C)C>>C=CCc1c(F)c(F)c(COC(=O)[C@@H]2[C@@H](C=C(C)C#N)C2(C)C)c(F)c1F -US06350749B1,1,Cc1n[nH]c2c1C(=O)CC(c1ccccc1Cl)C2.N=C(NN)NO>>Cc1n[nH]c2c1C(=NNC(=N)NO)CC(c1ccccc1Cl)C2 -US06875767B2,6,CCc1cc(CO[Si](C)(C)C(C)(C)C)cc(Nc2ncc(C#N)s2)n1>>CCc1cc(CO)cc(Nc2ncc(C#N)s2)n1 -US08071592B2,1,COc1cnc2ccc(=O)n(CCN3CCC(N)CC3)c2c1.O=Cc1cc2c(nn1)OCCO2>>COc1cnc2ccc(=O)n(CCN3CCC(NCc4cc5c(nn4)OCCO5)CC3)c2c1 -US20150141596A1,1,Nc1ccccc1.O=C1CCc2cccc(Br)c21>>Brc1cccc2c1C(Nc1ccccc1)CC2 -US04339443,6,COC[PH](=O)C(=O)CCC(=O)OC>>COC(=O)CCC(=O)[PH](=O)CO -US20070049618A1,2,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(O)c1cccc(OC(F)F)c1>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)c4cccc(OC(F)F)c4)c3C2=O)C(=O)N1 -US04668831,2,CC(C)(C)c1cc(OC(=S)Cl)ccc1Cl.CNc1ccccc1>>CN(C(=S)Oc1ccc(Cl)c(C(C)(C)C)c1)c1ccccc1 -US06939966B2,3,Nc1ncc(Br)cn1.OB(O)c1ccccc1F>>Nc1ncc(-c2ccccc2F)cn1 -US20090270350A1,7,COc1ccc(Cn2c(C)cc(OCc3ccccc3C#N)c(C)c2=O)c(OC)c1>>COc1ccc(Cn2c(C)cc(OCc3ccccc3CN)c(C)c2=O)c(OC)c1 -US05811439,1,Clc1ccc(CBr)cc1.O=Cc1cccc2[nH]ccc12>>O=Cc1cccc2c1ccn2Cc1ccc(Cl)cc1 -US05646173,1,CC(C)CBr.CC=CCC1Cc2ccc(O)cc2C1=O>>CC=CCC1Cc2ccc(OCC(C)C)cc2C1=O -US05843983,6,COCOc1ccc(F)cc1CCc1ccc(F)cc1>>Oc1ccc(F)cc1CCc1ccc(F)cc1 -US20110034507A1,1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.COC(=O)c1cccc(-c2ccc3ccc(O)cc3c2)c1>>COC(=O)c1cccc(-c2ccc3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3c2)c1 -US06030984,2,COCCNCCOC.O=C(O)c1cc(-c2ccc(-c3ccccc3)cc2)c(=O)n2ccc3ccsc3c12>>COCCN(CCOC)C(=O)c1cc(-c2ccc(-c3ccccc3)cc2)c(=O)n2ccc3ccsc3c12 -US08394858B2,2,CC(C)(C)[Si](C)(C)OC1CCC(O)(C(=O)O)CC1.C[C@@H](N)c1ccc(F)cc1>>C[C@@H](NC(=O)C1(O)CCC(O[Si](C)(C)C(C)(C)C)CC1)c1ccc(F)cc1 -US20040248872A1,1,O=C(O)c1ccc(Cl)nc1.OC1CCCCC1>>O=C(O)c1ccc(OC2CCCCC2)nc1 -US20080058552A1,1,Ic1ccccc1.c1ccc2cc(Nc3ccc(Nc4ccc5ccccc5c4)cc3)ccc2c1>>c1ccc(N(c2ccc(Nc3ccc4ccccc4c3)cc2)c2ccc3ccccc3c2)cc1 -US20150025068A1,6,COC(=O)c1ccc(NS(=O)(=O)c2cccc(-c3ccccc3O)c2)cc1O>>O=C(O)c1ccc(NS(=O)(=O)c2cccc(-c3ccccc3O)c2)cc1O -US20040097503A1,1,FC(F)(F)c1cc(Cl)nc(-c2ccncc2)n1.Nc1ccc2c(c1)OCO2>>FC(F)(F)c1cc(Nc2ccc3c(c2)OCO3)nc(-c2ccncc2)n1 -US08481540B2,9,CN(C)C(=O)c1ccc(N=[N+]=[N-])nc1>>CN(C)C(=O)c1ccc(N)nc1 -US04616014,1,Cc1nc(N(C)N)nnc1-c1ccccc1.N#Cc1ccc(C=O)cc1>>Cc1nc(N(C)N=Cc2ccc(C#N)cc2)nnc1-c1ccccc1 -US20090004185A1,6,C[C@H](NC(=O)OC(C)(C)C)c1ccc(NC(=O)c2ccc(Cl)nc2)cc1>>C[C@H](N)c1ccc(NC(=O)c2ccc(Cl)nc2)cc1 -US08759537B2,4,CC(C)(C)C(=O)NCc1ccc(Cl)c(N=C=S)c1Cl.Nc1cc(F)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1N>>CC(C)(C)C(=O)NCc1ccc(Cl)c(Nc2nc3cc(C(=O)N[C@@H]4CC[C@@H](C(F)(F)F)CC4)c(F)cc3[nH]2)c1Cl -US20090069430A1,1,CCCCI.COC(=O)c1ccc(OC)cc1O>>CCCCOc1cc(OC)ccc1C(=O)OC -US20100144694A1,1,CC1(C)NN(C2CC3CCC2C3)C1=O.Clc1ccccc1CBr>>CC1(C)C(=O)N(C2CC3CCC2C3)N1Cc1ccccc1Cl -US08071592B2,1,NC1CCN(CCn2c(=O)cnc3ccc(F)cc32)CC1.O=Cc1ccc2c(n1)NC(=O)CS2>>O=C1CSc2ccc(CNC3CCN(CCn4c(=O)cnc5ccc(F)cc54)CC3)nc2N1 -US20080269220A1,1,CC(C)Br.O=Cc1ccc(O)c(Br)c1>>CC(C)Oc1ccc(C=O)cc1Br -US20140010783A1,9,CC(C)(C)c1cc(N)ccc1C#N.S=C(Cl)Cl>>CC(C)(C)c1cc(N=C=S)ccc1C#N -US20060063784A1,1,CC(CC=O)c1ccccc1.Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1>>CC(CCNc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1)c1ccccc1 -US05834461,2,Cc1ccsc1C(=O)Cl.Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1>>Cc1ccsc1C(=O)Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1 -US08669271B2,3,CC(C)(C)OC(=O)N1CCC(C2(C)Cc3cc(Cl)ncc3O2)CC1.CC1(C)OB(C2=CCN(S(C)(=O)=O)CC2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(C2(C)Cc3cc(C4=CCN(S(C)(=O)=O)CC4)ncc3O2)CC1 -US20100323994A1,1,Nc1cc(Cl)ncn1.[O-]Cc1ccccc1>>Nc1cc(OCc2ccccc2)ncn1 -US20110124636A1,4,COC(=O)C(=O)C(Cl)c1cccc(OC)c1.NC(N)=S>>COC(=O)c1nc(N)sc1-c1cccc(OC)c1 -US07557212B2,3,C=Cc1ccc2cc(F)c(F)cc2n1.OC1c2cc(Br)ccc2OCc2ncccc21>>OC1c2cc(/C=C/c3ccc4cc(F)c(F)cc4n3)ccc2OCc2ncccc21 -US08729269B2,3,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=O)C(C)(C)C3)c(F)c2)C(=O)O1.Nc1ccc([N+](=O)[O-])cc1.[C-]#N>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(C#N)(Nc4ccc([N+](=O)[O-])cc4)C(C)(C)C3)c(F)c2)C(=O)O1 -US20070197626A1,6,CCOC(=O)Cc1ccc(OCC(=O)OC(C)(C)C)c(F)c1>>CCOC(=O)Cc1ccc(OCC(=O)O)c(F)c1 -US20120015958A1,2,COC(=O)c1coc(CN2CCNCC2)n1.O=C(Nc1ccc(C(=O)O)cc1)NC1CCC1>>COC(=O)c1coc(CN2CCN(C(=O)c3ccc(NC(=O)NC4CCC4)cc3)CC2)n1 -US20020037907A1,9,NO.O=C1c2ccccc2-c2c(OC[C@@H](O)CNCC3CCN(c4ccnc5cc(C(F)(F)F)ccc45)CC3)cccc21>>ON=C1c2ccccc2-c2c(OC[C@@H](O)CNCC3CCN(c4ccnc5cc(C(F)(F)F)ccc45)CC3)cccc21 -US20040167123A1,1,CC(C)CCBr.O=c1[nH]c2ncccc2c(=O)o1>>CC(C)CCn1c(=O)oc(=O)c2cccnc21 -US05190960,6,CN(CCn1c(=O)oc2cccnc21)Cc1ccccc1>>CNCCn1c(=O)oc2cccnc21 -US05641431,3,CCCCC[Si](CCC(=O)OCC)(CCC(=O)OCC)c1ccccc1>>CCCCC[Si]1(c2ccccc2)CCC(=O)C(C(=O)OCC)C1 -US20090270350A1,1,CC(C)(C)OC(N)=O.O=Cc1cc(F)ccc1CBr>>CC(C)(C)OC(=O)NCc1cc(F)ccc1CBr -US20020045747A1,2,CC(C)COC(=O)[C@H](C)N.CSc1cccc(CC(=O)O)c1>>CSc1cccc(CC(=O)N[C@@H](C)C(=O)OCC(C)C)c1 -US20080255083A1,1,C1CCNC1.O=c1cc(OCc2ccccc2)ccn1CCc1ccc(CO)s1>>O=c1cc(OCc2ccccc2)ccn1CCc1ccc(CN2CCCC2)s1 -US07329775B2,6,CC(C)(C)OC(=O)NC(CO)C(=O)c1ccccc1>>[NH3+]C(CO)C(=O)c1ccccc1 -US06699861B1,2,C#CCN(Cc1cc2c(=O)n(C)c(CN3CCN(c4ccccc4)CC3)nc2cc1Cl)c1ccc(C(=O)OC(C)(C)C)cc1.NCc1cccnc1>>C#CCN(Cc1cc2c(=O)n(C)c(CN3CCN(c4ccccc4)CC3)nc2cc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 -US07001895B2,3,COc1c(Br)cnn(-c2cccc(Cl)c2)c1=O.CSc1ccc(B(O)O)cc1>>COc1c(-c2ccc(SC)cc2)cnn(-c2cccc(Cl)c2)c1=O -US20080090839A1,1,C#CCBr.CC(C)(C)OC(=O)N1CCCC1COc1ccc(O)cc1>>C#CCOc1ccc(OCC2CCCN2C(=O)OC(C)(C)C)cc1 -US20130023541A1,1,CCN[C@H]1CCN(c2ncccc2C(=O)OC(C)C)C1.CCc1cccc(C=O)c1>>CCc1cccc(CN(CC)[C@H]2CCN(c3ncccc3C(=O)OC(C)C)C2)c1 -US06890947B2,1,CCOC(=O)C(Cc1ccc2[nH]c(C)cc2c1)OCC.Cc1oc(-c2ccccc2Cl)nc1CCl>>CCOC(=O)C(Cc1ccc2c(c1)cc(C)n2Cc1nc(-c2ccccc2Cl)oc1C)OCC -US04263207,1,C1COCCN1.COC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1N=C2Cl>>COC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1N=C2N1CCOCC1 -US20110201625A1,1,CC(C)(C)OC(=O)NCCCCBr.CNCCNC(=O)c1nc(Cl)c(N)nc1N>>CN(CCCCNC(=O)OC(C)(C)C)CCNC(=O)c1nc(Cl)c(N)nc1N -US08278325B2,2,CCCCOC(=O)c1nc(C)c2cc(Oc3ccc(F)cc3)ccc2c1O.C[C@H](N)C(=O)O>>Cc1nc(C(=O)N[C@@H](C)C(=O)O)c(O)c2ccc(Oc3ccc(F)cc3)cc12 -US20150232444A1,1,O=C1CCN(S(=O)(=O)c2ccccc2)CC1.OCCC1CCCCN1>>O=S(=O)(c1ccccc1)N1CCC(N2CCCCC2CCO)CC1 -US20150175602A1,1,Clc1nc2ccncc2nc1Cl.Fc1ccc(CN2CCNCC2)c(F)c1>>Fc1ccc(CN2CCN(c3nc4ccncc4nc3Cl)CC2)c(F)c1 -US20090099183A1,1,Cc1ccc(Cl)cc1-c1cc(Cl)nc(N)n1.Nc1ccc(CCO)cc1>>Cc1ccc(Cl)cc1-c1cc(Nc2ccc(CCO)cc2)nc(N)n1 -US20140050743A1,6,CC(C)(C)OC(=O)NCCCCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>NCCCCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 -US20150105373A1,3,CC[Mg+].COc1ccc(C(=O)N(C)OC)cn1>>CCC(=O)c1ccc(OC)nc1 -US20110105514A1,7,O=C(O)CCc1ccc(Cl)c(F)c1>>OCCCc1ccc(Cl)c(F)c1 -US20100087424A1,1,CC(C)(C)OC(=O)NC[C@@H]1CCNC1.CS(=O)(=O)OC[C@@H]1COc2c(F)cnc3ccc(=O)n1c23>>CC(C)(C)OC(=O)NC[C@@H]1CCN(C[C@@H]2COc3c(F)cnc4ccc(=O)n2c34)C1 -US08084448B2,3,C=Cc1cccnc1.O=C1CN(c2ccc(I)cc2OCc2ccccc2)S(=O)(=O)N1>>O=C1CN(c2ccc(/C=C/c3cccnc3)cc2OCc2ccccc2)S(=O)(=O)N1 -US05519019,7,CC(=O)N1N=C(c2ccc([N+](=O)[O-])cc2)c2cc3c(cc2CC1C)OCO3>>CC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2CC1C)OCO3 -US20090291950A1,1,COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(Cl)nc2c1OC1CCCC1.OCCO>>COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(OCCO)nc2c1OC1CCCC1 -US20040097730A1,6,CCOC(=O)Cn1c(Cl)cnc(N[C@@H](Cc2ccccc2)CN(C)C)c1=O>>CN(C)C[C@H](Cc1ccccc1)Nc1ncc(Cl)n(CC(=O)O)c1=O -US08431695B2,3,CC(C)(C)OC(=O)N1CCC(C(=O)c2cc(Br)c3c(N)ncnn23)C1.CC1(C)OB(c2ccc3cn(Cc4ccccc4)nc3c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(C(=O)c2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)C1 -US09108936B2,6,CCOC(=O)c1c(C)cc(N2CCOCC2)cc1C1CC1>>Cc1cc(N2CCOCC2)cc(C2CC2)c1C(=O)O -US20150218133A1,5,COc1cccc(Cl)c1-c1cc2ccc(N)cc2[nH]1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cccc(Cl)c1-c1cc2ccc(NC(=O)C(F)(F)F)cc2[nH]1 -US20080318923A1,6,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N(C)C>>CC(C)[C@H](N)C(=O)N(C)C -US20140335550A1,6,CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCNC(=O)C(F)(F)F)NC(=O)OC(C)(C)C>>CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCNC(=O)C(F)(F)F -US20130281490A1,2,CCCCCCCCOC(=O)Cl.C[C@H](O)[C@@H](N)C(=O)O>>CCCCCCCCOC(=O)N[C@@H](C(=O)O)[C@H](C)O -US20130217690A1,1,Cc1cccc(C)c1Br.OCC1CCNC1>>Cc1cccc(C)c1N1CCC(CO)C1 -US08003659B2,2,COc1ccc(C(C)=O)c(N)c1Cl.O=C(O)c1nc(C(F)(F)F)cs1>>COc1ccc(C(C)=O)c(NC(=O)c2nc(C(F)(F)F)cs2)c1Cl -US07906532B2,2,CC(C)(C)OC(=O)N1C[C@H](N)CC[C@@H]1CC1(O)CCOCC1.CC(C)n1nc(C(=O)O)c2ccccc21>>CC(C)n1nc(C(=O)N[C@@H]2CC[C@H](CC3(O)CCOCC3)N(C(=O)OC(C)(C)C)C2)c2ccccc21 -US05563142,2,CCNc1cccnc1N1CCNCC1.COc1c(C)cc(C(=O)O)cc1C>>CCNc1cccnc1N1CCN(C(=O)c2cc(C)c(OC)c(C)c2)CC1 -US08334236B2,7,COC(=O)c1cccnc1Nc1ccc2c(c1)OCCO2>>OCc1cccnc1Nc1ccc2c(c1)OCCO2 -US08987307B2,2,Cc1ccccc1-c1ccncc1NC1COC1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ccccc1-c1ccncc1N(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1COC1 -US20100273847A1,8,OCC12CC3CC(CC(C3)C1)C2>>O=CC12CC3CC(CC(C3)C1)C2 -US06586424B2,1,CC(=O)N1CCNCC1.O=Cc1ccnc(Cl)c1F>>CC(=O)N1CCN(Cc2ccnc(Cl)c2F)CC1 -US20100120793A1,2,CCOC(=O)C1CCNC1.CCOc1ccccc1C(=O)Cl>>CCOC(=O)C1CCN(C(=O)c2ccccc2OCC)C1 -US09051296B2,1,ClCCN1CCOCC1.O=C(c1ccc2[nH]ccc2c1)N1CCC(Oc2ccc(Cl)cc2)CC1>>O=C(c1ccc2c(ccn2CCN2CCOCC2)c1)N1CCC(Oc2ccc(Cl)cc2)CC1 -US20070232627A1,6,Cc1ccc2c(Nc3cc(C(=O)Nc4cccc(Br)c4)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1>>Cc1ccc2c(Nc3cc(C(=O)Nc4cccc(Br)c4)ccc3Sc3ccc(N)cc3)ncnc2n1 -US06277992B1,8,C=CC(O)c1cc(OCCCNC(=O)OC(C)(C)C)ccc1[N+](=O)[O-]>>C=CC(=O)c1cc(OCCCNC(=O)OC(C)(C)C)ccc1[N+](=O)[O-] -US20130274244A1,6,CCOC(=O)c1cnc2ccc(Br)cn12>>O=C(O)c1cnc2ccc(Br)cn12 -US04690705,3,Brc1cscc1Br.O=C(Cl)c1cccs1>>O=C(c1cccs1)c1scc(Br)c1Br -US08399674B2,1,COc1ccccc1CNc1ccc2cc(Br)ccc2n1.Nc1ncccn1>>COc1ccccc1CNc1ccc2cc(Nc3ncccn3)ccc2n1 -US06541505B1,1,N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(Cl)n4)cc3)cc12.NCCCO>>N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(NCCCO)n4)cc3)cc12 -US20130324526A1,3,CON(C)C(=O)c1ccc2nnc(C(C)c3ccc4ncc(Br)cc4c3)n2n1.C[Mg+]>>CC(=O)c1ccc2nnc(C(C)c3ccc4ncc(Br)cc4c3)n2n1 -US06878750B2,1,CCCCN(C)C(=O)CS(=O)(=O)CCI.CNCCOc1ccc(C2=C(c3ccccc3)CCCc3cc(OC4CCCCO4)ccc32)cc1>>CCCCN(C)C(=O)CS(=O)(=O)CCN(C)CCOc1ccc(C2=C(c3ccccc3)CCCc3cc(OC4CCCCO4)ccc32)cc1 -US20110112127A1,9,CSc1ncc(C(O)c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)cn1>>CSc1ncc(Cc2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)cn1 -US07851473B2,2,Cc1noc(NC(=O)OCC(Cl)(Cl)Cl)c1C.Clc1cccc(-c2csc(N3CCNCC3)n2)c1Cl>>Cc1noc(NC(=O)N2CCN(c3nc(-c4cccc(Cl)c4Cl)cs3)CC2)c1C -US08524730B2,2,CCOc1cc(C(=O)O)cc(OCC)c1-c1ccc(C(=O)OC)cc1.Cn1cc(-c2ccc3c(c2)C(=O)CC2(CCNCC2)O3)cn1>>CCOc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4cnn(C)c4)ccc2O3)cc(OCC)c1-c1ccc(C(=O)OC)cc1 -US06300363B1,7,CC(=O)Nc1c(C(=O)c2cccc([N+](=O)[O-])c2)[nH]c2cc(Cl)ccc12>>CC(=O)Nc1c(C(=O)c2cccc(N)c2)[nH]c2cc(Cl)ccc12 -US20130053344A1,6,CC(C)(C)OC(=O)NCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O>>NCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O -US20100087446A1,3,C#C[Si](C)(C)C.FC(F)(F)Oc1ccc(I)cc1>>C[Si](C)(C)C#Cc1ccc(OC(F)(F)F)cc1 -US08188101B2,6,CCN(CC1CCCO1)c1nc(Nc2ccc(-n3ccnc3C)cc2)nc2c1CN(C(=O)OC(C)(C)C)CC2>>CCN(CC1CCCO1)c1nc(Nc2ccc(-n3ccnc3C)cc2)nc2c1CNCC2 -US20040229874A1,7,CCc1cccn1Cc1ccc(-c2ccccc2-c2cccnc2)cc1>>CCc1cccn1Cc1ccc(-c2ccccc2C2CCCNC2)cc1 -US20150126503A1,1,COc1cc(-c2cc3ncccc3c(O)n2)cc(OC)c1OC.COc1ccc([C@H](C)N2C[C@H]([C@H](C)O)CC2=O)cc1>>COc1ccc([C@H](C)N2C[C@H]([C@@H](C)Oc3nc(-c4cc(OC)c(OC)c(OC)c4)cc4ncccc34)CC2=O)cc1 -US20100249123A1,2,CC(=O)NCC(C)(C)c1ccc(N)cc1-c1cccnc1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CNC(C)=O)c(-c3cccnc3)c2)cc1OC -US07414040B2,1,CC(C)(C)C1CCC(=O)CC1.CC(C)(C)OC(=O)NN>>CC(C)(C)OC(=O)NN=C1CCC(C(C)(C)C)CC1 -US20150011546A1,6,COC(=O)c1c(C)n(C(C)c2ccccc2)c2cccnc12>>Cc1c(C(=O)O)c2ncccc2n1C(C)c1ccccc1 -US20150266867A1,6,O=C(N[C@@H]1C(=O)N[C@@H]1CN1CCOC1=O)OCc1ccccc1>>N[C@@H]1C(=O)N[C@@H]1CN1CCOC1=O -US20040209886A1,1,CI.COc1ccccc1Oc1ccc(Nc2c(C#N)cnn3cc(NC(=O)OCCN4CCOCC4)c(C)c23)cc1>>COc1ccccc1Oc1ccc(Nc2c(C#N)cnn3cc(N(C)C(=O)OCCN4CCOCC4)c(C)c23)cc1 -US07094798B1,6,COc1cccc(-c2cc3[nH]c4ccc(O)cc4c3c3c2C(=O)NC3=O)c1>>O=C1NC(=O)c2c1c(-c1cccc(O)c1)cc1[nH]c3ccc(O)cc3c21 -US05510376,2,CC(=O)[O-].NC1CCCc2c(ccc(O)c2O)C1>>CC(=O)NC1CCCc2c(ccc(O)c2O)C1 -US20090093512A1,7,COC(=O)C12CN(Cc3ccccc3)CC1(c1cccc(OC)n1)C2>>COc1cccc(C23CN(Cc4ccccc4)CC2(CO)C3)n1 -US05192785,7,Cc1ccccc1OCC(=O)O>>Cc1ccccc1OCCO -US20070191429A1,6,CCOC(=O)COc1cc(C2CCCN(C(=O)c3sc(-c4ccc(C(F)(F)F)cc4)nc3C)C2)ccc1C>>Cc1ccc([C@@H]2CCCN(C(=O)c3sc(-c4ccc(C(F)(F)F)cc4)nc3C)C2)cc1OCC(=O)O -US20120157487A1,2,CCCn1cnc(CSc2ccc(Cl)cc2N)c1.O=S(=O)(Cl)c1cc2ccccc2o1>>CCCn1cnc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1 -US20150119390A1,1,COc1nn2cc(-c3nc4c(O)cccc4o3)nc2s1.OCc1cccc(-c2ccoc2)c1>>COc1nn2cc(-c3nc4c(OCc5cccc(-c6ccoc6)c5)cccc4o3)nc2s1 -US08034812B2,7,CC(=O)OCC(=O)Nc1cn2nc(Oc3cccc(NC(=O)c4cccc(C(F)(F)F)c4)c3)ccc2n1>>O=C(CO)Nc1cn2nc(Oc3cccc(NC(=O)c4cccc(C(F)(F)F)c4)c3)ccc2n1 -US04789395,8,CCOC(=O)c1c(C(F)(F)F)nc(C(F)F)c(SC(C)C)c1CC.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1c(C(F)(F)F)nc(C(F)F)c(S(=O)C(C)C)c1CC -US07576098B2,1,CCOc1cc(OC(C)C)c(F)c(C(Nc2ccc(-c3noc(C)n3)cc2)c2nc(-c3cn[nH]c3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1.CI>>CCOc1cc(OC(C)C)c(F)c(C(Nc2ccc(-c3noc(C)n3)cc2)c2nc(-c3cnn(C)c3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1 -US20100120775A1,6,CC[C@H](C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3nc(C(=O)OC)ccc3c2)cc1>>CC[C@H](C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3nc(C(=O)O)ccc3c2)cc1 -US20060046980A1,6,COc1c(F)cc(Br)cc1C(C)C>>CC(C)c1cc(Br)cc(F)c1O -US20080293716A1,2,COc1cccc([C@H](C)N)c1.O=C(O)c1ccc(-c2ccncc2)s1>>COc1cccc([C@H](C)NC(=O)c2ccc(-c3ccncc3)s2)c1 -US05032594,6,CCCn1c(=O)c2c(NC(C)=O)n[nH]c2n(Cc2ccccc2)c1=O>>CCCn1c(=O)c2c(N)n[nH]c2n(Cc2ccccc2)c1=O -US20120094992A1,1,COC(=O)C(C)Br.O=Cc1ccc([N+](=O)[O-])c(O)c1>>COC(=O)C(C)Oc1cc(C=O)ccc1[N+](=O)[O-] -US20050131014A1,1,COc1cccc(C=O)c1OC.Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>COc1cccc(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1OC -US08987279B2,3,Nc1nc(Cl)c2nnn(Cc3cccc(N4CCCC4=O)n3)c2n1.OB(O)c1ccccc1>>Nc1nc(-c2ccccc2)c2nnn(Cc3cccc(N4CCCC4=O)n3)c2n1 -US20080090805A1,3,CCCCNC(=O)c1ccc2c(c1)N=C(Cl)c1cc(Cl)ccc1S2.Clc1ccc([Zn+])s1>>CCCCNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)s1)c1cc(Cl)ccc1S2 -US20140303164A1,2,Cc1ccc(C)c2c1NC(=O)C2CC(=O)O.Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@@H](N)Cc3cc(F)cc(F)c3)c21>>Cc1ccc(C)c2c1NC(=O)C2CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(C#CC(C)(C)O)ccc1-c1ccc(Cl)c2c(NS(C)(=O)=O)nn(C)c12 -US04654344,8,CCSc1ccc(-c2nc3cnncc3[nH]2)c(OC)c1.OO>>CCS(=O)c1ccc(-c2nc3cnncc3[nH]2)c(OC)c1 -US08324176B2,9,CC(C)c1[nH]nc(O[C@@H]2O[C@H](COC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@H](OC(=O)C(C)(C)C)[C@H]2OC(=O)C(C)(C)C)c1Cc1ccc(OCCCCl)cc1OC1CCOCC1.[N-]=[N+]=[N-]>>CC(C)c1[nH]nc(O[C@@H]2O[C@H](COC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@H](OC(=O)C(C)(C)C)[C@H]2OC(=O)C(C)(C)C)c1Cc1ccc(OCCCN=[N+]=[N-])cc1OC1CCOCC1 -US04343811,2,CCCn1c(C)c(-c2ccncc2)c2cc(OC(C)(C)C(=O)O)ccc21.NC1CCCCC1>>CCCn1c(C)c(-c2ccncc2)c2cc(OC(C)(C)C(=O)NC3CCCCC3)ccc21 -US20040006141A1,6,COC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)cc1)Oc1cccnc1>>O=C(NCCOc1ccc(CC(Oc2cccnc2)C(=O)O)cc1)c1ccc(-c2ccccn2)cc1 -US07217710B2,1,CCOC(=O)c1cnc(SC)nc1Cl.CNN>>CCOC(=O)c1cnc(SC)nc1N(C)N -US05587112,6,COc1cc2c(cc1C(=O)O)oc1ccccc12>>O=C(O)c1cc2oc3ccccc3c2cc1O -US20090018123A1,2,COC(=O)Cl.NC[C@H]1CN(c2cc(F)c(N3CCC(n4ncnn4)CC3)c(F)c2)C(=O)O1>>COC(=O)NC[C@H]1CN(c2cc(F)c(N3CCC(n4ncnn4)CC3)c(F)c2)C(=O)O1 -US08466289B2,2,Cc1c(Nc2ccc(I)cc2F)c(N)c2n(c1=O)CCO2.O=S(=O)(Cl)C1CC(OCc2ccccc2)C1>>Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2CC(OCc3ccccc3)C2)c2n(c1=O)CCO2 -US20100120785A1,6,Cc1cccc(-c2nccnc2N2CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1cccc(-c2nccnc2N2CCNCC2)c1 -US20150087639A1,7,O=[N+]([O-])c1ccc(N2CCS(=O)(=O)CC2)c(F)c1>>Nc1ccc(N2CCS(=O)(=O)CC2)c(F)c1 -US20120225861A1,1,C[C@H](Nc1nc2ccc(O)cc2s1)C1CCCCC1.Fc1ccnc(Cl)c1>>C[C@H](Nc1nc2ccc(Oc3ccnc(Cl)c3)cc2s1)C1CCCCC1 -US07250410B2,7,CCN1C(=O)C(Cc2cccc(C#N)c2)N=C(c2ccccc2)c2cc(OC)c(OC)cc21>>CCN1C(=O)C(Cc2cccc(CN)c2)N=C(c2ccccc2)c2cc(OC)c(OC)cc21 -US20100152235A1,6,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(C(=O)OC(C)(C)C)C4)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNC4)no2)cc1C#N -US07683185B2,2,COC(=O)CCCCCS(=O)c1ccc(Cl)cc1.NO>>O=C(CCCCCS(=O)c1ccc(Cl)cc1)NO -US20110112085A1,3,CS(=O)(=O)Nc1cccc(B(O)O)c1.Clc1nc(N2CCOCC2)c2nc(I)sc2n1>>CS(=O)(=O)Nc1cccc(-c2nc3c(N4CCOCC4)nc(Cl)nc3s2)c1 -US20090149445A1,2,CC(=O)Cl.Nc1ccccc1C=C1c2ccccc2CCc2ccccc21>>CC(=O)Nc1ccccc1C=C1c2ccccc2CCc2ccccc21 -US20040138223A1,2,CN(C)c1ccc(CNc2ccccc2)cc1.O=C(O)C1CCCc2c(OCc3ccccc3)cccc21>>CN(C)c1ccc(CN(C(=O)C2CCCc3c(OCc4ccccc4)cccc32)c2ccccc2)cc1 -US20120189568A1,2,CCCCCC(=O)O.Nc1ccc(O)c(C(=O)O)c1>>CCCCCC(=O)Nc1ccc(O)c(C(=O)O)c1 -US20090253677A1,6,COc1ccc(CN2C(C)(C)CN(c3cc(F)ccc3C#N)S2(=O)=O)cc1>>CC1(C)CN(c2cc(F)ccc2C#N)S(=O)(=O)N1 -US20100056515A1,1,CC1CCCN1Cc1cc(Cl)cc(Cl)c1O.CCC(CC)c1ccc(OC)c2nc(Cl)n(C)c12>>CCC(CC)c1ccc(OC)c2nc(Oc3c(Cl)cc(Cl)cc3CN3CCCC3C)n(C)c12 -US05153210,1,CC(=O)CCl.O=C1CCC(c2ccc(O)cc2)=NN1>>CC(=O)COc1ccc(C2=NNC(=O)CC2)cc1 -US06632819B1,1,C[O-].O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(Cl)ncc(F)c12>>COc1ncc(F)c2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 -US08921389B2,7,COC(=O)c1ncc2c(cc(C#Cc3ccccc3)c(=O)n2Cc2ccccc2)c1O>>COC(=O)c1ncc2c(cc(CCc3ccccc3)c(=O)n2Cc2ccccc2)c1O -US20040254241A1,5,COCCl.O=Cc1ccc(O)cc1>>COCOc1ccc(C=O)cc1 -US20120270865A2,6,CCC(CC)C(Nc1ccc(C(=O)OC)cc1)c1sc2ccccc2c1C>>CCC(CC)C(Nc1ccc(C(=O)O)cc1)c1sc2ccccc2c1C -US20130178505A1,2,CO.O=C(O)c1cc(O)nc2ccccc12>>COC(=O)c1cc(O)nc2ccccc12 -US07053107B2,2,C[Si](C)(C)CCOCn1nc(C=Nn2cccc2)c2ccc(Nc3ccccc3C(=O)O)cc21.Cc1cc(CN)n(C)n1>>Cc1cc(CNC(=O)c2ccccc2Nc2ccc3c(C=Nn4cccc4)nn(COCC[Si](C)(C)C)c3c2)n(C)n1 -US04604402,7,CCCCC(NC(=O)c1ccccc1)C(=O)CN(C)C(=O)N1CCC[C@H]1C(=O)O>>CCCCC(NC(=O)c1ccccc1)C(O)CN(C)C(=O)N1CCC[C@H]1C(=O)O -US20050014786A1,7,O=[N+]([O-])c1cnc2ccc(Cl)cc2c1C(F)(F)F>>Nc1cnc2ccc(Cl)cc2c1C(F)(F)F -US20100022476A1,1,COc1cc(O)c2c(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)ncnc2c1.OCCCl>>COc1cc(OCCCl)c2c(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)ncnc2c1 -US20100130558A1,1,C[Si](C)(C)CCl.NCc1cccc(C(F)(F)F)c1>>C[Si](C)(C)CNCc1cccc(C(F)(F)F)c1 -US05420343,9,COC(=O)C1(CCc2ccc(C(C)(C)C)cc2C(C)(C)C)CCCC1=O>>CC(C)(C)c1ccc(CCC2CCCC2=O)c(C(C)(C)C)c1 -US20080287455A1,2,CS(=O)(=O)c1ccc(SCC(F)(F)F)c(C(=O)O)c1.Fc1cc(C(F)(F)F)cnc1N1CCNCC1>>CS(=O)(=O)c1ccc(SCC(F)(F)F)c(C(=O)N2CCN(c3ncc(C(F)(F)F)cc3F)CC2)c1 -US20080312273A1,1,N#Cc1cc2c(Cl)ccnc2cc1O.OCCOC1CCOCC1>>N#Cc1cc2c(Cl)ccnc2cc1OCCOC1CCOCC1 -US20140031355A1,2,CNOC.O=C(O)c1cnc2ccc(Cl)cc2c1Cl>>CON(C)C(=O)c1cnc2ccc(Cl)cc2c1Cl -US20150183804A1,1,C1O[C@@H]2CN[C@H]1C2.Cc1ccncc1C(=O)CN1c2nc(Cl)cc(=O)n2CC[C@H]1C(F)(F)F>>Cc1ccncc1C(=O)CN1c2nc(N3C[C@@H]4C[C@H]3CO4)cc(=O)n2CC[C@H]1C(F)(F)F -US20050148631A1,3,Cc1cccc(NS(=O)(=O)c2ccc(Br)cc2)n1.OB(O)c1ccc(Cl)cc1>>Cc1cccc(NS(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)n1 -US08163793B2,2,N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2)CC1.O=C(O)c1ccc(F)cc1>>N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2C(=O)c2ccc(F)cc2)CC1 -US20020068827A1,2,CC[C@H](N)c1ccccc1.O=C(O)c1c(O)c(-c2ccccc2)nc2ccccc12>>CC[C@H](NC(=O)c1c(O)c(-c2ccccc2)nc2ccccc12)c1ccccc1 -US04954499,9,CC1CC(=O)NN=C1c1ccc(Cl)c([N+](=O)[O-])c1.N>>CC1CC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1 -US08039493B2,1,CC(C)I.CS(=O)(=O)c1cccc(-c2ccc(CNS(=O)(=O)c3ccccc3C(F)(F)F)s2)c1>>CC(C)N(Cc1ccc(-c2cccc(S(C)(=O)=O)c2)s1)S(=O)(=O)c1ccccc1C(F)(F)F -US06964980B2,3,Brc1ccc2cc[nH]c2c1.OB(O)c1ccccc1>>c1ccc(-c2ccc3cc[nH]c3c2)cc1 -US08178549B2,3,COc1ncc(B(O)O)c(OC)n1.Cc1nc(I)sc1C>>COc1ncc(-c2nc(C)c(C)s2)c(OC)n1 -US05441949,4,Nc1ccc([N+](=O)[O-])cc1C(=O)O.OCC(O)CO>>O=C(O)c1cc([N+](=O)[O-])cc2cccnc12 -US20090286778A1,2,CCN=C=O.O=C(Nc1ccc2cc1CCc1cccc(c1)Nc1ncc(Cl)c(n1)N2)C1CCNCC1>>CCNC(=O)N1CCC(C(=O)Nc2ccc3cc2CCc2cccc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US08354411B2,2,CNOC.COc1cn(-c2cc(F)c(N3CCOCC3)cc2F)nc(C(=O)O)c1=O>>COc1cn(-c2cc(F)c(N3CCOCC3)cc2F)nc(C(=O)N(C)OC)c1=O -US20040006141A1,9,CCOC(=O)C(C)(Cc1ccc(OCCN=[N+]=[N-])cc1)Oc1ccc(C(C)C)cc1>>CCOC(=O)C(C)(Cc1ccc(OCCN)cc1)Oc1ccc(C(C)C)cc1 -US05420129,1,COc1ccc(Cl)c(Oc2c(CCl)ncnc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1.NCCO>>COc1ccc(Cl)c(Oc2c(CNCCO)ncnc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1 -US08829026B2,1,CCOC(=O)c1ccc(S(=O)(=O)NCc2ccc3c(cnn3CC)c2)c(Cl)c1.FC(F)(F)c1cnc(Cl)c(Cl)c1>>CCOC(=O)c1ccc(S(=O)(=O)N(Cc2ccc3c(cnn3CC)c2)c2ncc(C(F)(F)F)cc2Cl)c(Cl)c1 -US20080194535A1,1,CC(C)(C)OC(=O)N1CC2CNCC2C1.O=C1CCCC=CCO[C@@H]2C[C@H](NC[C@@H](O)[C@H](Cc3cc(F)cc(F)c3)N1)c1cc(Br)ccc12>>CC(C)(C)OC(=O)N1CC2CN(c3ccc4c(c3)[C@@H]3C[C@H]4OCC=CCCCC(=O)N[C@@H](Cc4cc(F)cc(F)c4)[C@H](O)CN3)CC2C1 -US20020031536A1,9,CCOC(=O)C1NN(c2ccc(C)cc2)C(=O)C1=O>>Cc1ccc(N2NCC(=O)C2=O)cc1 -US20100266504A1,1,C=O.CC(C)CNc1ccc2c(n1)CCN(Cc1ccccc1)C2>>CC(C)CN(C)c1ccc2c(n1)CCN(Cc1ccccc1)C2 -US20110039821A1,1,CN(C)C(=O)c1ccc(F)cc1F.COCC1Cc2c(O)cc(C(=O)Nc3ccn(C)n3)cc2O1>>COCC1Cc2c(Oc3ccc(C(=O)N(C)C)c(F)c3)cc(C(=O)Nc3ccn(C)n3)cc2O1 -US20100069629A1,1,CCN1CCN(C(=O)Cc2cccc(Br)c2)CC1.COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4)cn2)cc1>>CCN1CCN(C(=O)Cc2cccc(N3CCc4c(-c5cnc(N(Cc6ccc(OC)cc6)Cc6ccc(OC)cc6)nc5)nc(N5CCOCC5)nc43)c2)CC1 -US20130131092A1,7,CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2Cl)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2Cl)CC1 -US20060293344A1,3,Brc1cccc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(NC3CCCC3)n2)c1.OB(O)c1ccsc1>>c1cc(-c2ccsc2)cc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(NC3CCCC3)n2)c1 -US20060058372A1,6,COC(=O)c1cccc(C)c1-c1ccc(OC(F)(F)F)cc1>>Cc1cccc(C(=O)O)c1-c1ccc(OC(F)(F)F)cc1 -US08946260B2,1,Cc1ccncc1I.O=C1NCCc2cc(Cl)c(Cl)cc21>>Cc1ccncc1N1CCc2cc(Cl)c(Cl)cc2C1=O -US20150111870A1,1,C1CNC1.Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(Cl)c(CC(F)(F)F)c(Cl)c2c1>>Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(N3CCC3)c(CC(F)(F)F)c(Cl)c2c1 -US06103718,1,COc1ccc(C2=NNC(=O)[C@H]3CC=CC[C@@H]23)cc1OC.ClCc1ccncc1>>COc1ccc(C2=NN(Cc3ccncc3)C(=O)[C@H]3CC=CC[C@@H]23)cc1OC -US05998433,1,OCCCCCCc1ccccc1.c1cc2c(o1)CNCC2>>c1ccc(CCCCCCN2CCc3ccoc3C2)cc1 -US20040010009A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(NC/C=C/c3cccc(C#N)c3)cc2)CC1.CC(C)=O>>CC(C)N(C/C=C/c1cccc(C#N)c1)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US07326699B2,2,COCCOC(=O)Cl.NC[C@@H]1C[C@H](n2cc(-c3cccc(OCc4ccccc4)c3)c3c(N)ncnc32)C1>>COCCOC(=O)NC[C@@H]1C[C@H](n2cc(-c3cccc(OCc4ccccc4)c3)c3c(N)ncnc32)C1 -US07491728B2,6,CCOC(=O)C(C)C1(C)OCCO1>>CC(C(=O)O)C1(C)OCCO1 -US07064124B2,1,BrCc1ccccc1.COc1c(C)c(Cc2ccc(O)c(C=O)c2)c(OC)c(OC)c1OC>>COc1c(C)c(Cc2ccc(OCc3ccccc3)c(C=O)c2)c(OC)c(OC)c1OC -US07268128B2,1,CN1CCNCC1.COc1cc(C=O)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1>>COc1cc(CN2CCN(C)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1 -US06586441B2,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CSc1nc(N)nc(-c2ccc(Br)o2)c1C#N>>C=C(OCC)c1ccc(-c2nc(N)nc(SC)c2C#N)o1 -US20130090340A1,3,CC(C)(C)NC(=O)N1CCn2c(c(C(N)=O)c(Br)c2C2CC2)C1.OB(O)c1cccc(C(F)(F)F)c1>>CC(C)(C)NC(=O)N1CCn2c(c(C(N)=O)c(-c3cccc(C(F)(F)F)c3)c2C2CC2)C1 -US20130029962A1,6,COC(=O)C(C)c1ccc(COCCO[Si](C)(C)C(C)(C)C)nc1>>COC(=O)C(C)c1ccc(COCCO)nc1 -US20100240658A1,7,CC1CCCCN1c1ccc(C(=O)O)cc1[N+](=O)[O-]>>CC1CCCCN1c1ccc(C(=O)O)cc1N -US08912186B2,2,CCOC(=O)CCNc1ccccc1.O=C(Cl)Cc1ccc(Cl)c(Cl)c1>>CCOC(=O)CCN(C(=O)Cc1ccc(Cl)c(Cl)c1)c1ccccc1 -US04684651,1,O=C(CCCl)c1ccc2c(c1)OCO2.c1ccc(N2CCNCC2)cc1>>O=C(CCN1CCN(c2ccccc2)CC1)c1ccc2c(c1)OCO2 -US05948793,6,CC(C)(C)OC(=O)N1CC[C@H]1COc1cccnc1>>c1cncc(OC[C@@H]2CCN2)c1 -US20040259912A1,2,CCC(=O)c1cc(N)ccc1OCc1ccc(C(C)(C)C)cc1.COc1ccc(N=C=O)cc1OC>>CCC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OCc1ccc(C(C)(C)C)cc1 -US06103903,1,Fc1ccc(-c2cc(Cl)c3sccc3n2)cc1.NCC1CCNCC1>>Fc1ccc(-c2cc(NCC3CCNCC3)c3sccc3n2)cc1 -US20030073836A1,2,Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O.NCc1ccc(Cl)cc1>>Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)NCc1ccc(Cl)cc1 -US20070185078A1,2,NNC(=O)c1ccc(Br)cc1.O=C(Cl)CCl>>O=C(CCl)NNC(=O)c1ccc(Br)cc1 -US20070099955A1,1,Cc1ccc2c(c1OC(C)C)C[C@@H](C1CCNCC1)O[C@H]2CNC=O.O=Cc1ccc(F)cc1>>Cc1ccc2c(c1OC(C)C)CC(C1CCN(Cc3ccc(F)cc3)CC1)OC2CNC=O -US20080275018A1,6,CC(C)(C)OC(=O)NCCC[C@@H](CC(=O)NCCNC(=O)OC(C)(C)C)NC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCCC[C@@H](CC(=O)NCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](N)CCCNC(=O)OC(C)(C)C -US07557127B2,1,CCOC(=O)/C=C/c1ccc(N(C(=O)OC(C)(C)C)[C@@H]2CCNC2)nc1.Cc1ccc(CCl)cc1C>>CCOC(=O)/C=C/c1ccc(N(C(=O)OC(C)(C)C)[C@@H]2CCN(Cc3ccc(C)c(C)c3)C2)nc1 -US20040023956A1,6,C[C@H](C(=O)OC(C)(C)C)N1OC[C@@H](O)[C@@H](O)C1=O>>C[C@H](C(=O)O)N1OC[C@@H](O)[C@@H](O)C1=O -US20150072969A1,2,CC1(CO)COC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC2(C)COC2)cc1 -US20100216746A1,9,N#Cc1cc(Br)cc(Oc2c(Cl)ccc(CN=[N+]=[N-])c2F)c1>>N#Cc1cc(Br)cc(Oc2c(Cl)ccc(CN)c2F)c1 -US20130005721A1,8,CCOC(=O)c1cc2cc(CO)ccn2c1-c1ccc(F)cc1>>CCOC(=O)c1cc2cc(C=O)ccn2c1-c1ccc(F)cc1 -US20070010694A1,7,CN=C1CCC(c2ccc(Cl)c(Cl)c2)c2ccccc21>>CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21 -US08314088B2,1,CC(C)N(Cc1ccccc1)c1cnc(C=O)c(Cl)n1.OCCNCc1ccccc1>>CC(C)N(Cc1ccccc1)c1cnc(CN(CCO)Cc2ccccc2)c(Cl)n1 -US06048854,6,CCOC(=O)CC1CCN(c2ccc(C#N)cc2)CC1>>N#Cc1ccc(N2CCC(CC(=O)O)CC2)cc1 -US04766233,1,CC(C)Oc1cc(-n2ncc(=O)[nH]c2=O)c(Cl)cc1Cl.CI>>CC(C)Oc1cc(-n2ncc(=O)n(C)c2=O)c(Cl)cc1Cl -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN2CCCCC2=O)c1=O.C[C@H](N)CO>>C[C@@H](CO)NC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN2CCCCC2=O)c1=O -US08921397B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>Cc1ccc(S(=O)(=O)N[C@@H]2CC[C@@H](CCN3CCCCC3c3coc4cccc-4c3)CC2)cc1 -US05376653,1,COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(CCl)C2=O.Cc1cc(C(=O)O)on1>>COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COC(=O)c1cc(C)no1)C2=O -US05041462,2,CC(=O)OCC(=O)Cl.CNc1cccc(N)c1C#N>>CNc1cccc(NC(=O)COC(C)=O)c1C#N -US20090186900A1,1,CI.Oc1ccc(Oc2ccccc2)cc1>>COc1ccc(Oc2ccccc2)cc1 -US04315766,8,O=C(OO)c1cccc(Cl)c1.O=c1oc(-c2cccc(SC(F)(F)F)c2)nc2ccccc12>>O=c1oc(-c2cccc(S(=O)C(F)(F)F)c2)nc2ccccc12 -US04076821,1,O=C1CCC(c2ccc(F)cc2)(c2ccc(F)cc2)CC1.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=c1[nH]c2ccccc2n1C1CCN(C2CCC(c3ccc(F)cc3)(c3ccc(F)cc3)CC2)CC1 -US06323235B1,1,COC(=O)CBr.OCCc1coc2c(O)cccc12>>COC(=O)COc1cccc2c(CCO)coc12 -US06268391B1,3,CCCC[Sn](C#N)(CCCC)CCCC.O=C1Cc2ccc(Br)cc2N1>>N#Cc1ccc2c(c1)NC(=O)C2 -US05663334,9,Cc1ccc(S(=O)(=O)C(NC=O)c2ccc(F)cc2)cc1>>[C-]#[N+]C(c1ccc(F)cc1)S(=O)(=O)c1ccc(C)cc1 -US20140343033A1,1,C[C@H](N)c1nc2ccn(C)c2cc1-c1ccnn1C.Nc1nc(N)c(Cl)c(Cl)n1>>C[C@H](Nc1nc(N)nc(N)c1Cl)c1nc2ccn(C)c2cc1-c1ccnn1C -US20090023725A1,3,Fc1cc(Br)ccc1[Zn]I.O=C(Cl)c1ccccn1>>O=C(c1ccccn1)c1ccc(Br)cc1F -US20140275172A1,7,COC(=O)c1cccc2oc(C)cc12>>Cc1cc2c(CO)cccc2o1 -US20120323040A1,7,NC(=O)C1=CCCc2cc(Sc3ccccc3)cc(F)c21>>NC(=O)[C@@H]1CCCc2cc(Sc3ccccc3)cc(F)c21 -US20150197499A1,6,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1c1ncc(C#C[Si](C)(C)C)[nH]1>>C#Cc1cnc([C@@H]2C[C@H]3C[C@H]3N2C(=O)OC(C)(C)C)[nH]1 -US20080200471A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1CCCN1>>CC(C)(C)OC(=O)N1CCCC1C(=O)O -US04326055,3,CC(c1ccc2c(c1)C(C)(C)CC2(C)C)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.CCOC(=O)c1ccc(C=O)cc1>>CCOC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CC3(C)C)cc1 -US20070249670A1,2,CC[C@@H](OCc1ccccc1)[C@H](N)C(=O)OC.Nc1cc2ccccc2cc1C(=O)O>>CC[C@@H](OCc1ccccc1)[C@H](NC(=O)c1cc2ccccc2cc1N)C(=O)OC -US20150232454A1,6,COc1cnc(-c2ccc(F)cc2)[nH]c1=O>>O=c1[nH]c(-c2ccc(F)cc2)ncc1O -US05506267,6,COC(=O)CCSCC(O)C(C)O>>CC(O)C(O)CSCCC(=O)O -US04279912,6,CCOC(=O)c1cn2c(cc(Cl)c3ccccc32)n1>>O=C(O)c1cn2c(cc(Cl)c3ccccc32)n1 -US06451819B2,1,O=CCOCc1ccccc1.O=S(=O)(c1ccc(O)cc1)C1CCNC1>>O=S(=O)(c1ccc(O)cc1)C1CCN(CCOCc2ccccc2)C1 -US20050014812A1,1,CCOC(=O)C(C)(C)CCOc1ccc(NC(C)=O)c(N)c1.ClCc1ccc(Cl)cc1Cl>>CCOC(=O)C(C)(C)CCOc1ccc(NC(C)=O)c(NCc2ccc(Cl)cc2Cl)c1 -US07964622B2,1,BrCCCBr.COc1cc(C)ccc1O>>COc1cc(C)ccc1OCCCBr -US20100311748A1,1,C1COCCN1.O=Cc1ncccc1F>>O=Cc1ncccc1N1CCOCC1 -US20070161654A1,2,Cc1onc(-c2ccccc2)c1-c1cn(-c2cccc(C(=O)O)c2)cn1.NC1CCCC1>>Cc1onc(-c2ccccc2)c1-c1cn(-c2cccc(C(=O)NC3CCCC3)c2)cn1 -US20130158276A1,7,O=C1CCOc2ccccc21>>O[C@@H]1CCOc2ccccc21 -US20080004360A1,1,O=S(=O)([O-])CCCBr.Oc1cc(Cl)ccc1Cl>>O=S(=O)([O-])CCCOc1cc(Cl)ccc1Cl -US20080214495A1,2,COCCN.Cn1nc(N2CCC(CN3C(=O)CN(S(=O)(=O)c4ccc5c(Cl)c[nH]c5c4)CC3C(=O)O)CC2)ccc1=O>>COCCNC(=O)[C@@H]1CN(S(=O)(=O)c2ccc3c(Cl)c[nH]c3c2)CC(=O)N1CC1CCN(c2ccc(=O)n(C)n2)CC1 -US20060160864A1,6,CCCCOCCOc1ccc(-c2cc(/C=C(\C)C(=O)OCC)c3c(c2)CCCN3C)cc1>>CCCCOCCOc1ccc(-c2cc(/C=C(\C)C(=O)O)c3c(c2)CCCN3C)cc1 -US20100190747A1,1,O=[N+]([O-])c1ccc(CBr)cc1.OCC(F)(F)F>>O=[N+]([O-])c1ccc(COCC(F)(F)F)cc1 -US20120035214A1,7,CC(C)(C)OC(=O)N1CC[C@](O)(c2ccc(F)c(F)c2)[C@@H](C(=O)O)C1>>CC(C)(C)OC(=O)N1CC[C@](O)(c2ccc(F)c(F)c2)[C@@H](CO)C1 -US07553798B2,3,CCCC[Sn](CCCC)(CCCC)c1cccs1.O=[N+]([O-])c1ccccc1I>>O=[N+]([O-])c1ccccc1-c1cccs1 -US20140336106A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](CC1CC1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](CC1CC1)C(=O)O -US20040023974A1,1,COC(=O)CBr.COc1ccc(N)c(OC)c1>>COC(=O)CNc1ccc(OC)cc1OC -US20150181867A1,2,CCCO[C@@H](CCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)[C@@H](CCC(C)C)[C@H](C)O>>CCCO[C@H]1CCC[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H](C)[C@@H]1CCC(C)C -US20150087823A1,2,C1CCC(N2CCNCC2)CC1.CCCCCCC/C=C/C(=O)O>>CCCCCCC/C=C/C(=O)N1CCN(C2CCCCC2)CC1 -US08470816B2,2,CC(=O)Nc1cccc(C(=O)O)c1.CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1>>CC(=O)Nc1cccc(C(=O)N2CC[C@@H](N(C)C(=O)c3ccc(Cl)cc3)[C@H](c3ccc(Cl)c(Cl)c3)C2)c1 -US20070105872A1,6,CCOC(=O)c1ccn(CCOC)n1>>COCCn1ccc(C(=O)O)n1 -US20120101082A1,2,Cc1ccc2c(c1)Nc1c(cnn1C)CN2C(=O)c1ccc(CN)c(F)c1.O=C(Cl)C1CC1>>Cc1ccc2c(c1)Nc1c(cnn1C)CN2C(=O)c1ccc(CNC(=O)C2CC2)c(F)c1 -US20140142083A1,6,CCN(c1cc(Cl)cc(C(=O)OC)c1Br)C1CCOCC1>>CCN(c1cc(Cl)cc(C(=O)O)c1Br)C1CCOCC1 -US20090247526A1,6,CCOC(=O)c1cnc(Nc2nc(C)cs2)cc1Oc1cccc2ccccc12>>Cc1csc(Nc2cc(Oc3cccc4ccccc34)c(C(=O)O)cn2)n1 -US20130345207A1,6,CC(C)(C)OC(=O)NC12CC3CC1CC(C(N)=O)(C3)C2>>NC(=O)C12CC3CC(C1)C(N)(C3)C2 -US06797823B1,1,COc1cc2nccc(Cl)c2cc1OC.Nc1cc(Cl)c(O)c(Cl)c1>>COc1cc2nccc(Oc3c(Cl)cc(N)cc3Cl)c2cc1OC -US20090221642A1,2,COC(=O)Cl.Cc1ccc2[nH]c(=O)n(C3CCN(C4(C)CCNC4)CC3)c2c1>>COC(=O)N1CCC(C)(N2CCC(n3c(=O)[nH]c4ccc(C)cc43)CC2)C1 -US06583135B2,1,CC(C)(C)OC(=O)N1CCc2[nH]c3ccccc3c2CC1.O=S(CCCl)c1ccccc1>>CC(C)(C)OC(=O)N1CCc2c(n(CCS(=O)c3ccccc3)c3ccccc23)CC1 -US07812037B2,3,Cc1ncc(CN(C(=O)OC(C)(C)C)c2ccc(C#N)cc2)c(C=O)c1OCc1cccc(C#N)c1.[Mg+]C1CC1>>Cc1ncc(CN(C(=O)OC(C)(C)C)c2ccc(C#N)cc2)c(C(O)C2CC2)c1OCc1cccc(C#N)c1 -US06780873B2,1,CC(C)(C)OC(=O)NCCCCN.O=[N+]([O-])c1cnc2ccccc2c1Cl>>CC(C)(C)OC(=O)NCCCCNc1c([N+](=O)[O-])cnc2ccccc12 -US05434186,1,BrCCCCCBr.COC(=O)C=Cc1ccccc1O>>COC(=O)/C=C/c1ccccc1OCCCCCBr -US06303818B1,9,CO/N=C(/C(=O)OC)c1ccccc1CBr>>CON=C(C(=O)OC)c1ccccc1C -US05110940,3,CCOC(=O)CC#N.O=C(c1ccc(F)cc1)c1ccc(F)cc1>>CCOC(=O)C(C#N)=C(c1ccc(F)cc1)c1ccc(F)cc1 -US20150038438A1,6,COC(=O)c1c(OCc2ccccc2)c2c(n(Cc3ccc(OC)cc3OC)c1=O)-c1cc3cc(CO[Si](C)(C)C(C)(C)C)n(C)c3cc1C=CC2>>COC(=O)c1c(OCc2ccccc2)c2c(n(Cc3ccc(OC)cc3OC)c1=O)-c1cc3cc(CO)n(C)c3cc1C=CC2 -US20070208034A1,1,Cc1ccc([N+](=O)[O-])cc1N.Clc1cc(Cl)ncn1>>Cc1ccc([N+](=O)[O-])cc1Nc1cc(Cl)ncn1 -US20100022529A1,7,O=[N+]([O-])c1ccc(Oc2cc3cn[nH]c3cc2-c2ccncc2)c(F)c1>>Nc1ccc(Oc2cc3cn[nH]c3cc2-c2ccncc2)c(F)c1 -US20110135671A1,1,CCCCOc1nc(N)c2nc(OC)n(CCCCCl)c2n1.CN1CCNCC1>>CCCCOc1nc(N)c2nc(OC)n(CCCCN3CCN(C)CC3)c2n1 -US20040209921A1,1,CC(C)(C)OC(=O)n1c(CCl)nc2ccccc21.CC(C)(NCCCCN1C(=O)c2ccccc2C1=O)c1ccccn1>>CC(C)(C)OC(=O)n1c(CN(CCCCN2C(=O)c3ccccc3C2=O)C(C)(C)c2ccccn2)nc2ccccc21 -US08017782B2,2,CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(OCC=CC(=O)O)c(OCC)c1.COCCN>>CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(OCC=CC(=O)NCCOC)c(OCC)c1 -US20060223826A1,1,C=O.CC(C)(C)OC(=O)NCc1cccc(N)c1>>CNc1cccc(CNC(=O)OC(C)(C)C)c1 -US20090093459A1,6,CC(C)(C)OC(=O)N[C@H]1CSc2c(Br)cccc2NC1=O>>N[C@H]1CSc2c(Br)cccc2NC1=O -US06964983B2,6,COC(=O)COc1ccc(SCc2ccc(OCc3ccc(Cl)cc3)cc2)c2c1CCC2>>O=C(O)COc1ccc(SCc2ccc(OCc3ccc(Cl)cc3)cc2)c2c1CCC2 -US20050131016A1,2,CC1(C)OCC(CN2C(=O)C(N)Cc3ccccc32)CO1.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>CC1(C)OCC(CN2C(=O)C(NC(=O)c3cc4cc(Cl)ccc4[nH]3)Cc3ccccc32)CO1 -US06121271,2,Cc1cc(-c2c3ccccc3c(Br)c3sc(C)c(C)c23)cc(C)c1OS(=O)(=O)c1ccc(C(=O)OC(C)(C)C)c(O)c1.O=C(Cl)Cc1ccccc1>>Cc1cc(-c2c3ccccc3c(Br)c3sc(C)c(C)c23)cc(C)c1OS(=O)(=O)c1ccc(C(=O)OC(C)(C)C)c(OC(=O)Cc2ccccc2)c1 -US08008315B2,6,COC(=O)c1cc(COCC(CO)(Cc2ccccc2)NC(=O)OC(C)(C)C)cc(-c2ccccc2C#N)c1>>CC(C)(C)OC(=O)NC(CO)(COCc1cc(C(=O)O)cc(-c2ccccc2C#N)c1)Cc1ccccc1 -US05278148,6,CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)C(O)CN1CCCCC1>>N[C@@H](CC1CCCCC1)C(O)CN1CCCCC1 -US07122543B2,2,C1COCCN1.COc1c(C)c(Cc2ccc(C(=O)O)c(-c3cccnc3)c2)c(OC)c(OC)c1OC>>COc1c(C)c(Cc2ccc(C(=O)N3CCOCC3)c(-c3cccnc3)c2)c(OC)c(OC)c1OC -US06673786B1,6,COC(=O)CCc1cccc(CNC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)NCc1cccc(CCC(=O)O)c1 -US04552894,7,CCOC(=O)c1cccc(OCCF)c1>>OCc1cccc(OCCF)c1 -US08957070B2,4,CCOC(=O)CC(=O)CCl.CN(c1cccc2cc(C(N)=S)[nH]c12)S(=O)(=O)c1cccs1>>CCOC(=O)Cc1csc(-c2cc3cccc(N(C)S(=O)(=O)c4cccs4)c3[nH]2)n1 -US20100081670A1,2,COc1nc(C)cnc1N.Cc1c(Cl)cccc1S(=O)(=O)Cl>>COc1nc(C)cnc1NS(=O)(=O)c1cccc(Cl)c1C -US20150266862A1,1,CC(C)COc1cccc(C=O)c1.OC1CCNC1>>CC(C)COc1cccc(CN2CCC(O)C2)c1 -US08008504B2,7,Cc1cn(-c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)cn1>>Cc1cn(-c2cc(N)cc(C(F)(F)F)c2)cn1 -US05011839,7,CCCOc1ccc2ccccc2c1CNc1c([N+](=O)[O-])nn(CC)c(=O)c1Br>>CCCOc1ccc2ccccc2c1CNc1c(N)nn(CC)c(=O)c1Br -US20060287321A1,1,CI.O=C(CCc1ccc([N+](=O)[O-])cc1O)N1CCCC1>>COc1cc([N+](=O)[O-])ccc1CCC(=O)N1CCCC1 -US08008504B2,1,Cc1c[nH]cn1.N#Cc1cc(F)cc(C(F)(F)F)c1>>Cc1cn(-c2cc(C#N)cc(C(F)(F)F)c2)cn1 -US20100256048A1,1,Brc1nnc(-c2ccc(-c3cnc(N4CCC(OC5CCCCC5)CC4)nc3)cc2)s1.OCC1CCNCC1>>OCC1CCN(c2nnc(-c3ccc(-c4cnc(N5CCC(OC6CCCCC6)CC5)nc4)cc3)s2)CC1 -US07737166B2,6,Cc1c(C2=CC(O[Si](C)(C)C(C)(C)C)CC2)c(F)c2oc(C3CC3)nc2c1C#N>>Cc1c(C2=CC(O)CC2)c(F)c2oc(C3CC3)nc2c1C#N -US06051712,1,BrCc1ccc2ccccc2c1.CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)C(O)C1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)C(OCc2ccc3ccccc3c2)C1 -US04833144,8,O=C(OO)c1cccc(Cl)c1.O=c1c2ccccc2nc(SCc2ccncc2)n1-c1ccccc1>>O=c1c2ccccc2nc(S(=O)Cc2ccncc2)n1-c1ccccc1 -US06346521B1,2,CCOP(=O)(Cc1ccc(N)cc1)OCC.COc1cc2c(cc1OC)C(=O)CS[C@@H](C(=O)O)C2>>CCOP(=O)(Cc1ccc(NC(=O)[C@H]2Cc3cc(OC)c(OC)cc3C(=O)CS2)cc1)OCC -US20100075968A1,1,CN1C(=O)NCC1C(=O)OC(C)(C)C.COc1ccnc(Cl)n1>>COc1ccnc(N2CC(C(=O)OC(C)(C)C)N(C)C2=O)n1 -US20070167447A1,3,COC(=O)c1cnc2c(c1)c(C1CCCCC1)c(Br)n2CC(=O)OC(C)(C)C.OB(O)c1ccccc1>>COC(=O)c1cnc2c(c1)c(C1CCCCC1)c(-c1ccccc1)n2CC(=O)OC(C)(C)C -US08431695B2,6,CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cc(-c4ccc5cn(Cc6ccccc6)nc5c4)c4c(N)ncnn34)cc2)CC1>>Nc1ncnn2c(-c3ccc(N4CCNCC4)cc3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12 -US07572809B2,3,Clc1nc(Nc2cc[nH]n2)cc2ccccc12.OB(O)c1cccnc1>>c1cncc(-c2nc(Nc3cc[nH]n3)cc3ccccc23)c1 -US20080146614A1,10,COC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OC)cc2)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OC)cc2)c1CBr -US20130274469A1,2,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.Cn1ccc(N)n1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2ccn(C)n2)cn1 -US20150166485A1,3,FC(F)(F)c1nc2cc(Cl)c(Cl)cc2[nH]1.OB(O)c1ccc(Cl)c(Cl)c1>>FC(F)(F)c1nc2cc(Cl)c(-c3ccc(Cl)c(Cl)c3)cc2[nH]1 -US06013654,1,ClCc1cn2cc(Cl)ccc2n1.FC(F)(F)c1cccc(N2CCNCC2)c1>>FC(F)(F)c1cccc(N2CCN(Cc3cn4cc(Cl)ccc4n3)CC2)c1 -US20040138286A1,6,CCCN1C2CCC1CC(N(c1ccc3c(cnn3C3CCCCO3)c1)S(C)(=O)=O)C2>>CCCN1C2CCC1CC(N(c1ccc3[nH]ncc3c1)S(C)(=O)=O)C2 -US20100075960A1,6,C[C@@H](Oc1cc(-n2cnc3ccc(S(C)(=O)=O)cc32)sc1C(N)=O)c1cccc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1Cl>>C[C@@H](Oc1cc(-n2cnc3ccc(S(C)(=O)=O)cc32)sc1C(N)=O)c1cccc(OC2CCNCC2)c1Cl -US20070105819A1,3,Clc1ccc([Zn+])nc1.O=C(NN1CCCCC1)c1cccc2c1C(Cl)=Nc1ccccc1S2>>O=C(NN1CCCCC1)c1cccc2c1C(c1ccc(Cl)cn1)=Nc1ccccc1S2 -US20060018848A1,3,C[Si](C)(C)COc1ccc(C=O)cc1.NC(=O)CC(N)=O>>C[Si](C)(C)COc1ccc(C=C(C(N)=O)C(N)=O)cc1 -US20090163586A1,2,Nc1cc(F)c(F)cc1S(N)(=O)=O.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>NS(=O)(=O)c1cc(F)c(F)cc1NS(=O)(=O)c1cccc(Cl)c1Cl -US07402585B2,2,COc1cc2c(Nc3cc(CC(=O)O)[nH]n3)ncnc2cc1OCCC1CCN(CCOC(C)(C)C)CC1.Nc1cccc(F)c1>>COc1cc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2cc1OCCC1CCN(CCOC(C)(C)C)CC1 -US20040220178A1,7,CCOC(=O)N1CC[C@H]2[C@@H](C1)c1cccc3c1N2CC(=O)N3C>>CCOC(=O)N1CC[C@H]2[C@@H](C1)c1cccc3c1N2CCN3C -US20060100218A1,2,CCOc1ccc2ccccc2c1C(=O)Cl.COc1ccc(-c2c[nH]c3ncccc23)cc1OC>>CCOc1ccc2ccccc2c1C(=O)n1cc(-c2ccc(OC)c(OC)c2)c2cccnc21 -US20120122923A1,1,Clc1ccc2c(Cl)ccnc2c1.N[C@H]1CC[C@@H](N)CC1>>N[C@@H]1CC[C@H](Nc2ccnc3cc(Cl)ccc23)CC1 -US20080058293A1,6,CC(C)(C)[Si](C)(C)OCCN[C@H]1CCN(c2ccc3c(NC(=O)CCc4ccccc4Cl)c(Cl)ccc3n2)C1>>O=C(CCc1ccccc1Cl)Nc1c(Cl)ccc2nc(N3CC[C@H](NCCO)C3)ccc12 -US20100087471A1,1,CN1CCN(c2ccc(Br)cc2)CC1.c1ccc2c3c([nH]c2c1)C1CCN(CC1)C3>>CN1CCN(c2ccc(-n3c4c(c5ccccc53)CN3CCC4CC3)cc2)CC1 -US08106215B2,2,Cc1nc(C(=O)O)c(-c2ccc(Cl)cc2)s1.Cc1nc2sccn2c1C(=O)NC[C@H]1NC[C@@H]2CCC[C@H]12>>Cc1nc(C(=O)N2C[C@@H]3CCC[C@@H]3[C@H]2CNC(=O)c2c(C)nc3sccn23)c(-c2ccc(Cl)cc2)s1 -US20150038708A1,2,CNCC(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>CN(CC(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1)S(=O)(=O)c1ccc(C#N)cc1 -US04349684,6,COC(=O)CCCCCCCn1cc(-c2ccccc2)n(-c2ccc(C)cc2)c1=O>>Cc1ccc(-n2c(-c3ccccc3)cn(CCCCCCCC(=O)O)c2=O)cc1 -US20100200054A1,3,Brc1cc(Br)cc(-c2nc3ccccc3s2)c1.OB(O)c1cccnc1>>Brc1cc(-c2cccnc2)cc(-c2nc3ccccc3s2)c1 -US20150284391A1,1,C=CCBr.COc1cc2cc(O)nc(Cl)c2cc1F>>C=CCOc1cc2cc(OC)c(F)cc2c(Cl)n1 -US07423056B2,9,CCOC(=O)N1CC2Cc3cc(CO)sc3C2C1>>CCOC(=O)N1CC2Cc3cc(C)sc3C2C1 -US20070219235A1,2,CC(C)c1ccccc1Nc1nc2ccc(C(=O)O)cc2[nH]1.COc1n[nH]c2cc(N)ccc12>>COc1n[nH]c2cc(NC(=O)c3ccc4nc(Nc5ccccc5C(C)C)[nH]c4c3)ccc12 -US20150266822A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1.Cc1ncc(CNC(=O)c2cc(Br)cc(C(=O)N3CCCC3)c2)cn1>>Cc1ccc(-c2cc(C(=O)NCc3cnc(C)nc3)cc(C(=O)N3CCCC3)c2)nc1 -US20140142074A1,6,CCOC(=O)c1ccnc(N(C(=O)OC(C)(C)C)S(C)(=O)=O)c1>>CC(C)(C)OC(=O)N(c1cc(C(=O)O)ccn1)S(C)(=O)=O -US07601868B2,3,CC(CNC(=O)c1ccc(Br)cc1F)c1ccc(CN2CCCC2)cc1.OB(O)c1ccc(Cl)cc1>>CC(CNC(=O)c1ccc(-c2ccc(Cl)cc2)cc1F)c1ccc(CN2CCCC2)cc1 -US20120209005A1,1,CC(=O)c1nn(C)c(-c2ccc3c(c2)CCC3)c1O.NNC(=O)c1ccc(C(=O)NCc2ccncc2)s1>>CC(=NNC(=O)c1ccc(C(=O)NCc2ccncc2)s1)c1nn(C)c(-c2ccc3c(c2)CCC3)c1O -US20100160324A1,7,O=[N+]([O-])c1c[nH]nc1-n1cccn1>>Nc1c[nH]nc1-n1cccn1 -US20140336190A1,3,Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1.Cc1noc(C)c1-c1cc(I)c2nc(C3CC3)n(C)c2c1>>Cc1n[nH]c(C)c1-c1cc(-c2c(C)noc2C)cc2c1nc(C1CC1)n2C -US04478837,1,CC(C)=O.NNc1cc2c(nn1)CCN(C(=O)c1ccc(Cl)cc1)C2>>CC(C)=NNc1cc2c(nn1)CCN(C(=O)c1ccc(Cl)cc1)C2 -US20130296327A1,3,CC1(C)OC(=O)CC(=O)O1.O=C1CCCC1>>CC1(C)OC(=O)C(=C2CCCC2)C(=O)O1 -US20140094462A1,6,O=C(C[C@@H]1CC=CC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O[C@H](c2ccccc2)CNC1=O)NCc1ccc(Cl)cc1>>N[C@H]1CC=CC[C@@H](CC(=O)NCc2ccc(Cl)cc2)C(=O)NC[C@@H](c2ccccc2)OC1=O -US03957782,2,CCOc1nc2c(nc1C(=O)Cl)c(C)nn2CC.Nc1nccs1>>CCOc1nc2c(nc1C(=O)Nc1nccs1)c(C)nn2CC -US20140049823A1,1,C=CCBr.CCOP(OCC)OCC>>C=CCP(=O)(OCC)OCC -US20050154042A1,2,CC(C)n1c(C=O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)O.NCc1ccc(F)cc1>>CC(C)n1c(C=O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)NCc1ccc(F)cc1 -US08178577B2,2,COC(=O)CCCCCN.O=C(O)C=C1c2ccccc2Oc2ccccc21>>COC(=O)CCCCCNC(=O)C=C1c2ccccc2Oc2ccccc21 -US08426541B2,7,CC(=O)Oc1c(Cl)cc(Cl)cc1C(=O)N[C@@H](Cc1ccccc1)C(=O)O>>O=C(N[C@@H](Cc1ccccc1)C(=O)O)c1cc(Cl)cc(Cl)c1O -US20080312281A1,6,CC(=O)OCCCc1ccnc(C#N)c1>>N#Cc1cc(CCCO)ccn1 -US20090105295A1,6,Cc1c(C)n2nnnc2c2nc(CCl)n(CCCCNC(=O)OC(C)(C)C)c12>>Cc1c(C)n2nnnc2c2nc(CCl)n(CCCCN)c12 -US20140275546A1,1,NCc1ccccc1.O=CC1CC=CCC1>>C1=CCC(/C=N/Cc2ccccc2)CC1 -US20150183791A1,3,CC(C)CCn1ccc(B(O)O)cc1=O.Cc1cnc2ccc(Cl)nn12>>Cc1cnc2ccc(-c3ccn(CCC(C)C)c(=O)c3)nn12 -US20040180934A1,6,COC(=O)CC1CCn2c1c(Sc1ccc(Cl)cc1)c1c(S(C)(=O)=O)cc(OC)cc12>>COc1cc(S(C)(=O)=O)c2c(Sc3ccc(Cl)cc3)c3n(c2c1)CCC3CC(=O)O -US20060069013A1,6,CCOC(=O)c1cc2c(OC)ccc(C=O)c2o1>>COc1ccc(C=O)c2oc(C(=O)O)cc12 -US20070049571A1,1,O=C(CCl)N1CCN(C2CCC2)CC1.O=C(OCc1ccccc1)N1CCNCC1>>O=C(CN1CCN(C(=O)OCc2ccccc2)CC1)N1CCN(C2CCC2)CC1 -US05843983,1,C[SiH](C)O[C@]1(CCBr)C[C@H](C(C)(C)C)CN1C(=O)OC(C)(C)C.Oc1ccc(F)cc1CCc1ccc(F)c(F)c1>>C[SiH](C)O[C@@]1(CCOc2ccc(F)cc2CCc2ccc(F)c(F)c2)C[C@H](C(C)(C)C)CN1C(=O)OC(C)(C)C -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.O=Cc1ccc(-c2ccc(OC(F)(F)F)cc2)o1>>CC(C)C(=O)Nc1cccc(C2CCN(Cc3ccc(-c4ccc(OC(F)(F)F)cc4)o3)CC2)c1 -US20140057896A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCn2c(cc3c2CCCC3)C1=O.Cn1cc(Br)cc(Nc2cc3n(n2)CCOC3)c1=O>>CC(=O)OCc1c(-c2cc(Nc3cc4n(n3)CCOC4)c(=O)n(C)c2)cccc1N1CCn2c(cc3c2CCCC3)C1=O -US08153624B2,9,BrC(Br)(Br)Br.OCc1c(-c2c(Cl)cccc2Cl)noc1C1CC1>>Clc1cccc(Cl)c1-c1noc(C2CC2)c1CBr -US04547451,1,C=CC(=O)O.COC(=O)CBr>>C=CC(=O)OCC(=O)OC -US20070276017A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCCCC(=O)O>>CN(CCCC(=O)O)C(=O)OC(C)(C)C -US20130338367A1,1,O=C(Nc1cnn(-c2cccnc2)c1)C(Br)CCCBr>>O=C1C(Br)CCCN1c1cnn(-c2cccnc2)c1 -US05753017,1,CCBr.CCNc1cccc(C)n1>>CCN(CC)c1cccc(C)n1 -US20060287363A1,2,Nc1cccc([N+](=O)[O-])c1.O=C(Cl)c1ccc(F)cc1Cl>>O=C(Nc1cccc([N+](=O)[O-])c1)c1ccc(F)cc1Cl -US20080293775A1,4,CS(=O)(=O)c1ccc(Oc2cc(Cl)ccc2CCC#N)c(Cl)c1.[N-]=[N+]=[N-]>>CS(=O)(=O)c1ccc(Oc2cc(Cl)ccc2CCc2nnn[nH]2)c(Cl)c1 -US20050075499A1,3,CN(C)C=O.COC(=O)c1cc(NC(=O)OC(C)(C)C)cc2[nH]ccc12>>COC(=O)c1cc(NC(=O)OC(C)(C)C)cc2[nH]cc(C=O)c12 -US20130345181A1,1,CC(C)(C)OC(=O)n1cc(-c2cc3cnc(Br)cc3n2C(=O)OC(C)(C)C)cn1.Nc1ccc(OCCN2CCOCC2)cc1>>CC(C)(C)OC(=O)n1cc(-c2cc3cnc(Nc4ccc(OCCN5CCOCC5)cc4)cc3n2C(=O)OC(C)(C)C)cn1 -US20140274689A1,3,Clc1ccc(-n2cnc(Br)c2)cc1.OB(O)c1ccco1>>Clc1ccc(-n2cnc(-c3ccco3)c2)cc1 -US20140080798A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(N)cc2)CC1.Cc1cnc(Cl)nc1CCc1ccccc1CC(N)=O>>Cc1cnc(Nc2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)cc2)nc1CCc1ccccc1CC(N)=O -US20080009530A1,2,COCCOc1ccc(/C=C/C(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1.N#Cc1cccc(S(N)(=O)=O)c1>>COCCOc1ccc(/C=C/C(=O)NS(=O)(=O)c2cccc(C#N)c2)c(Oc2ncc(C(F)(F)F)cc2Cl)c1 -US20120283271A1,2,Nc1ccn(C[C@H](O)CO)n1.O=C(O)[C@H](CC1CCCC1)N1Cc2c(cccc2C(F)(F)F)C1=O>>O=C(Nc1ccn(C[C@H](O)CO)n1)[C@H](CC1CCCC1)N1Cc2c(cccc2C(F)(F)F)C1=O -US05532363,1,C=COCC.O=C1N[C@H](c2ccccc2)[C@@H]1O>>CCOC(C)O[C@@H]1C(=O)N[C@@H]1c1ccccc1 -US05190689,2,C=C(C)C(=O)Cl.CCCCCCCc1ccc(O)c(CCCCCCCCCCO)c1>>C=C(C)C(=O)OCCCCCCCCCCc1cc(CCCCCCC)ccc1O -US05708187,2,CN(C)C1CCc2[nH]c3ccc(N)cc3c2C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc3[nH]c4c(c3c2)CC(N(C)C)CC4)cc1 -US04988809,6,O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ncc(-c3ccccc3)cn2)CC1>>NCCCCN1CCN(c2ncc(-c3ccccc3)cn2)CC1 -US04386211,2,CCOC(=O)Cl.Cc1cc(N)sn1>>CCOC(=O)Nc1cc(C)ns1 -US04343811,2,C=CCNCC=C.Cc1c(-c2ccc(Cl)cc2)c2cc(OC(C)(C)C(=O)O)ccc2n1C>>C=CCN(CC=C)C(=O)C(C)(C)Oc1ccc2c(c1)c(-c1ccc(Cl)cc1)c(C)n2C -US20140005175A1,1,COCCBr.O=[N+]([O-])c1cccc(O)c1>>COCCOc1cccc([N+](=O)[O-])c1 -US20090325952A1,6,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(NC(=O)OC(C)(C)C)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(N)c1 -US20070259881A1,1,CC(C)(C)OC(=O)NCC(O)CN.O=[N+]([O-])c1cnc2ccccc2c1Cl>>CC(C)(C)OC(=O)NCC(O)CNc1c([N+](=O)[O-])cnc2ccccc12 -US20150025068A1,2,COC(=O)c1ccc(N)cc1O.O=S(=O)(Cl)c1cc(F)c(Br)cc1F>>COC(=O)c1ccc(NS(=O)(=O)c2cc(F)c(Br)cc2F)cc1O -US20040010023A1,6,CCOC(=O)CCCNc1nc2ccccc2[nH]1>>O=C(O)CCCNc1nc2ccccc2[nH]1 -US07507740B2,1,OCCn1ncc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c21>>Fc1cccc(COc2ccc(N3CCn4ncc5ncnc3c54)cc2Cl)c1 -US20040132772A1,7,CC(=O)N(C1=CC(C)N(Cc2ccccc2)c2ccccc21)c1ccccc1>>CC(=O)N(c1ccccc1)C1CC(C)N(Cc2ccccc2)c2ccccc21 -US08389527B2,2,COc1ccc(CN(c2ccc(C)cn2)c2cc(Cl)nn3c(C(=O)O)cnc23)cc1.Nc1ccncc1>>COc1ccc(CN(c2ccc(C)cn2)c2cc(Cl)nn3c(C(=O)Nc4ccncc4)cnc23)cc1 -US20130237537A1,6,COC(=O)c1cncc2c1CCN(Cc1ccccc1)C2>>COC(=O)c1cncc2c1CCNC2 -US20090131468A1,3,C#CC1CC1.CC(C)Oc1cc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cnc1Cl>>CC(C)Oc1cc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cnc1C#CC1CC1 -US06881733B1,6,C[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1c1cc(F)c(F)c2ccoc12>>C[C@@H]1CNCC[C@H]1c1cc(F)c(F)c2ccoc12 -US20080274075A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(CCl)OC(=O)CCl>>CC(C)(C)OC(=O)N1CCN(C(=O)CCl)CC1 -US20080096861A1,1,CC(C)(C)OC(=O)N1CCN(CCCCl)CC1.CN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21>>CN(Cc1nc2ccccc2n1CCCN1CCN(C(=O)OC(C)(C)C)CC1)C1CCCc2cccnc21 -US07067534B1,1,CC(=O)c1cccc(O)c1.CC(C)C(=O)Nc1cccc(C2CCN(CCCCCC(O)c3ccccc3)CC2)c1>>CC(=O)c1cccc(OC(CCCCCN2CCC(c3cccc(NC(=O)C(C)C)c3)CC2)c2ccccc2)c1 -US20050182138A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)C[C@H](N)[C@@H](O)CC(=O)O>>CC(C)C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)O -US20080221114A1,2,C[C@H]1CCCNC1.Cn1nc(N2c3cc(F)ccc3CC2C(=O)O)ccc1=O>>C[C@H]1CCCN(C(=O)C2Cc3ccc(F)cc3N2c2ccc(=O)n(C)n2)C1 -US06376502B1,2,COc1cccc(CN)c1.CS(=O)(=O)Cl>>COc1cccc(CNS(C)(=O)=O)c1 -US20070197636A1,6,COc1cc([N+](=O)[O-])c(NC(C)=O)cc1F>>COc1cc([N+](=O)[O-])c(N)cc1F -US20100216788A1,2,CC(C)(C)C(F)(F)c1cccc(Oc2ccc(Nc3ncnc4ccn(CCN)c34)cc2Cl)c1.CC(C)(O)CC(=O)O>>CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(F)(F)C(C)(C)C)c4)c(Cl)c3)c21 -US20140011810A1,2,C=CC(=O)Cl.COc1cc(N2CCN(C)CC2)ccc1Nc1nnc(C(=O)c2cccc(N)c2)s1>>C=CC(=O)Nc1cccc(C(=O)c2nnc(Nc3ccc(N4CCN(C)CC4)cc3OC)s2)c1 -US07592477B2,1,CCCCCCCCCCCc1noc(-c2ccc(C=O)cc2)n1.C[C@@H](N)c1ccc(C(F)(F)F)cc1>>CCCCCCCCCCCc1noc(-c2ccc(CN[C@H](C)c3ccc(C(F)(F)F)cc3)cc2)n1 -US20120022098A1,6,COc1cccc(C(=O)c2c[nH]c3ncc(Br)cc23)c1F>>O=C(c1cccc(O)c1F)c1c[nH]c2ncc(Br)cc12 -US20140296254A1,9,Cc1ccc(C(N=[N+]=[N-])C2(C)CCCO2)o1>>Cc1ccc(C(N)C2(C)CCCO2)o1 -US20100056515A1,1,CCC(CC)c1ccc(Cl)c2nc(Cl)[nH]c12.COc1cc(Cl)cc(C)c1N>>CCC(CC)c1ccc(Cl)c2nc(Nc3c(C)cc(Cl)cc3OC)[nH]c12 -US20070276138A1,1,CO[C@](C(=O)O)(c1ccccc1)C(F)(F)F.O[C@@H]1CCC[C@H](Oc2ccc(-c3ccccc3)cc2)C1>>CO[C@](C(=O)O[C@H]1CCC[C@@H](Oc2ccc(-c3ccccc3)cc2)C1)(c1ccccc1)C(F)(F)F -US20030176454A1,1,Cc1ncc(-c2cccc(N)c2)n1C.Clc1cc(-c2ccccc2)ncn1>>Cc1ncc(-c2cccc(Nc3cc(-c4ccccc4)ncn3)c2)n1C -US20090221653A1,1,CC(C)(C)OC(=O)N(CCSCCC=O)CCc1cccc(Cl)c1Cl.NC[C@H](O)c1ccc(O)c2[nH]c(=O)sc12>>CC(C)(C)OC(=O)N(CCSCCCNC[C@H](O)c1ccc(O)c2[nH]c(=O)sc12)CCc1cccc(Cl)c1Cl -US08309581B2,1,COC(=O)c1ccc(CBr)cc1.Oc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2n1Cc1ccccc1>>COC(=O)c1ccc(COc2cc(Cl)ccc2-c2nc3cc(F)c(F)cc3n2Cc2ccccc2)cc1 -US06521643B1,7,C[SiH](C)OCc1ccnc(-c2cccc([N+](=O)[O-])c2)c1C(C)(C)C>>C[SiH](C)OCc1ccnc(-c2cccc(N)c2)c1C(C)(C)C -US20120035053A1,5,Cc1ccc(-c2ccc(Cl)cc2)cc1C1C(=O)CC(CC=O)CC1=O.OCCCO>>Cc1ccc(-c2ccc(Cl)cc2)cc1C1C(=O)CC(CC2OCCCO2)CC1=O -US20150218133A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc([N+](=O)[O-])cc1N>>COc1ccc([N+](=O)[O-])cc1NC(=O)OC(C)(C)C -US20100022538A1,2,Nc1nc(O)ncc1F.O=S(=O)(Cl)c1ccccc1>>Nc1nc(OS(=O)(=O)c2ccccc2)ncc1F -US20090124596A1,3,CC1(C)OB(c2ccc(O)cc2C=O)OC1(C)C.O=C(N[C@H]1CC[C@@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(I)c3)c2=O)CC1)c1cn2cc(F)ccc2n1>>O=Cc1cc(O)ccc1-c1cccc(-n2c(=O)n([C@@H]3CC[C@H](NC(=O)c4cn5cc(F)ccc5n4)CC3)c(=O)c3cc(F)cnc32)c1 -US05703107,6,CCOC(=O)c1c(NCCC(=O)c2cccc(F)c2)c2c(Cl)cc(Cl)cc2n1C(=O)OC(C)(C)C>>CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCCC(=O)c1cccc(F)c1 -US04013658,1,CCCI.O=c1c(-c2ccccc2)c[nH]nc1-c1ccccc1>>CCCn1cc(-c2ccccc2)c(=O)c(-c2ccccc2)n1 -US20100256134A1,2,CCS(N)(=O)=O.Cc1cc(F)ccc1Nc1c(C(=O)N2CCC(c3ccccc3)CC2)cnc2c(C(=O)O)cnn12>>CCS(=O)(=O)NC(=O)c1cnn2c(Nc3ccc(F)cc3C)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12 -US20090111867A1,6,Cc1noc(C)c1CN1C(=O)c2ccccc2C1c1c(C)n(CC(=O)OC(C)(C)C)c2ccccc12>>Cc1noc(C)c1CN1C(=O)c2ccccc2C1c1c(C)n(CC(=O)O)c2ccccc12 -US20060116383A1,6,COC(=O)CC(C)n1cnc2ccc(N)cc21>>CC(CC(=O)O)n1cnc2ccc(N)cc21 -US20070054916A1,3,CNc1ncc2cc(Br)cnc2n1.Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1B1OC(C)(C)C(C)(C)O1>>CNc1ncc2cc(-c3cc(C(=O)Nc4cccc(C(F)(F)F)c4)ccc3C)cnc2n1 -US20080262056A1,1,CCI.O=C1Nc2ccccc2C1=O>>CCN1C(=O)C(=O)c2ccccc21 -US20020040023A1,1,CC[Si](CC)(CC)OC(CI)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1.COc1ccc(-c2nc(CS(=O)(=O)c3ccc(CCN)cc3)no2)cc1>>CC[Si](CC)(CC)O[C@@H](CNCCc1ccc(S(=O)(=O)Cc2noc(-c3ccc(OC)cc3)n2)cc1)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1 -US07790895B2,3,N#Cc1cccc(-c2ccncc2C=O)c1.[Mg+]c1ccccc1>>N#Cc1cccc(-c2ccncc2C(O)c2ccccc2)c1 -US07649001B2,1,N#Cc1ccc(F)c2ccsc12.OCCC1CCNC1>>N#Cc1ccc(N2CCC(CCO)C2)c2ccsc12 -US20120289500A1,2,Nn1nc(N2CCOCC2)c2ccccc2c1=O.O=C(O)Cc1cccc2ccccc12>>O=C(Cc1cccc2ccccc12)Nn1nc(N2CCOCC2)c2ccccc2c1=O -US20150065505A1,2,CC(C)(C)OC(=O)NC1CCNc2ccccc21.CCOC(=O)Cl>>CCOC(=O)N1CCC(NC(=O)OC(C)(C)C)c2ccccc21 -US20140303164A1,5,Cn1nc(N)c2cccc(Br)c21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cn1nc(NC(=O)C(F)(F)F)c2cccc(Br)c21 -US20130065923A1,6,C[C@H]1CCCN1C1CCN(C(=O)OC(C)(C)C)CC1>>C[C@H]1CCCN1C1CCNCC1 -US20070219214A1,1,CN(C)C(=O)C1CCCCN1C1CCNCC1.CN(C[C@@H](CC=O)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1>>CN(C)C(=O)[C@H]1CCCCN1C1CCN(CC[C@H](CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 -US06521643B1,7,O=Cc1cccnc1-c1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(-c2ncccc2CO)c1 -US08426420B2,2,CC(C)(C)OC(=O)N1CCNCC1.CCCOC(=O)Cl>>CCCOC(=O)N1CCN(C(=O)OC(C)(C)C)CC1 -US07199239B2,1,CCOC(=O)C(C)(C)Oc1ccc(CNCc2ccc(C(F)(F)F)cc2)cc1C.FC(F)(F)c1ccc(-c2cccc(Br)n2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(CN(Cc2ccc(C(F)(F)F)cc2)c2cccc(-c3ccc(C(F)(F)F)cc3)n2)cc1C -US07504410B2,2,CCCS(=O)(=O)Cl.NCCCNc1nc(Nc2cccc(NC(=O)N3CCCC3)c2)ncc1Br>>CCCS(=O)(=O)NCCCNc1nc(Nc2cccc(NC(=O)N3CCCC3)c2)ncc1Br -US20100305092A1,1,CNC.O=Cc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1>>CN(C)Cc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1 -US06417382B1,7,COC(=O)c1cccc(COc2ccc(C#N)cc2)c1>>N#Cc1ccc(OCc2cccc(CO)c2)cc1 -US20090171095A1,1,CONC(=O)C(Br)CCBr>>CON1CCC(Br)C1=O -US04751303,3,CN(C)C=O.COCOc1c(C)c(Br)c(OCOC)c(OC)c1OC>>COCOc1c(C)c(C=O)c(OCOC)c(OC)c1OC -US20120094964A1,6,CC(C)(C)OC(=O)CN(c1cccc(C(F)(F)F)c1)S(=O)(=O)c1ccccc1>>O=C(O)CN(c1cccc(C(F)(F)F)c1)S(=O)(=O)c1ccccc1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCCCN(C)S(C)(=O)=O.Cc1[nH]c2ccc(O)cc2c1C>>COc1cc2c(Oc3ccc4[nH]c(C)c(C)c4c3)ncnc2cc1OCCCN(C)S(C)(=O)=O -US20140051679A1,2,CC(C)OC(C(=O)O)c1ccccc1.Nc1ccc2[nH]nc(I)c2c1>>CC(C)OC(C(=O)Nc1ccc2[nH]nc(I)c2c1)c1ccccc1 -US20050113370A1,1,CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(N)cc21.FC(F)(F)c1cccc(Br)c1>>CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(Nc3cccc(C(F)(F)F)c3)cc21 -US20150197511A1,2,Nc1cccc(OC(F)(F)F)c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cccc(OC(F)(F)F)c1)Oc1ccccc1 -US06001867,1,COC(=O)CBr.Oc1ccc(-c2c(Br)ccc3sc4ccccc4c23)cc1>>COC(=O)COc1ccc(-c2c(Br)ccc3sc4ccccc4c23)cc1 -US20140140956A1,7,COC(=O)c1cc(Br)c2[nH]ccc2c1>>OCc1cc(Br)c2[nH]ccc2c1 -US20090099200A1,2,NCCC1CC1.O=C(O)c1cnc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)s1>>O=C(NCCC1CC1)c1cnc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)s1 -US05250570,2,Cc1cc(N)cc(C)c1S(=O)(=O)C[N+](=O)[O-].O=C(Cl)COc1ccccc1>>Cc1cc(NC(=O)COc2ccccc2)cc(C)c1S(=O)(=O)C[N+](=O)[O-] -US08193378B2,4,N#CC1CCN(C(=O)OCc2ccccc2)C1.[N-]=[N+]=[N-]>>O=C(OCc1ccccc1)N1CCC(c2nnn[nH]2)C1 -US20110301146A1,6,COc1ccc(C(=O)NC2CCC(C(=O)O)CC2)c2nc(-c3cccs3)[nH]c12>>O=C(NC1CCC(C(=O)O)CC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 -US20150259354A1,10,C=CC(=O)N1CCc2[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn3c2C1.Cl>>NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c3c([nH]c12)CCN(C(=O)CCCl)C3 -US05948819,7,CCOC(=O)C(=O)c1ccccc1COC1CCCCO1>>CCOC(=O)C(O)c1ccccc1COC1CCCCO1 -US06313117B1,1,CNCc1ccccc1.COC(=O)CBr>>COC(=O)CN(C)Cc1ccccc1 -US20120022075A1,6,COc1cc(Br)cc(OC)c1>>COc1cc(O)cc(Br)c1 -US06025496,1,CCOCCBr.c1c[n-]cn1>>CCOCCn1ccnc1 -US05840917,1,CC(=O)[O-].Clc1sccc1CBr>>CC(=O)OCc1ccsc1Cl -US20110295004A1,6,CC(=O)Oc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1>>Oc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 -US20140080802A1,3,Nc1cc(Br)ccc1[N+](=O)[O-].OB(O)c1cccs1>>Nc1cc(-c2cccs2)ccc1[N+](=O)[O-] -US20150175601A1,6,C=CC(=O)Nc1cccc(-c2c(COC(C)=O)ccc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc23)c1>>C=CC(=O)Nc1cccc(-c2c(CO)ccc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc23)c1 -US05670675,2,CC(C)CC(=O)Cl.O=C1NC(Cc2ccccc2)CO1>>CC(C)CC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1 -US05741926,1,Nc1ccccc1F.O=C(CBr)OCc1ccccc1>>O=C(CNc1ccccc1F)OCc1ccccc1 -US20070197605A1,7,COC(=O)C1CCCC(N(Cc2ccccc2)Cc2ccccc2)C1>>OCC1CCCC(N(Cc2ccccc2)Cc2ccccc2)C1 -US06498172B1,2,CC(C)(C)OC(=O)COc1cccc(CNCc2ccc(-n3cccn3)cc2)c1.O=S(=O)(Cl)c1cccc(F)c1>>CC(C)(C)OC(=O)COc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2cccc(F)c2)c1 -US20110059957A1,3,CC(C)(C)OC(=O)N1CCN(c2ccc(C=O)nc2)CC1.COC(=O)/C=C/c1cc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cs1>>COC(=O)/C=C/c1cc(C=Cc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cn2)cs1 -US20050261302A1,6,CC(C)(C)OC(=O)N1CCN(CC(=O)NC2C3CC4CC(C3)CC2C4)CC1>>O=C(CN1CCNCC1)NC1C2CC3CC(C2)CC1C3 -US20110092553A1,3,COC(=O)CNc1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(Br)cc2)cc1.OB(O)c1cccc(C(F)(F)F)c1>>COC(=O)CNc1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(-c3cccc(C(F)(F)F)c3)cc2)cc1 -US20140371324A1,1,COc1cc(CCC(C)=O)ccc1O.NCc1ccc(C(F)(F)F)cc1>>COc1cc(CCC(C)NCc2ccc(C(F)(F)F)cc2)ccc1O -US20150018310A1,6,COC(=O)c1ccccc1Sc1ccc2c(c1)NC(=O)/C2=C1\C=C(N2CCOCC2)C(C)(C)O1>>CC1(C)O/C(=C2/C(=O)Nc3cc(Sc4ccccc4C(=O)O)ccc32)C=C1N1CCOCC1 -US04333940,1,CCCCCCCCCCCCCCCCBr.COC(=O)c1ccc(N)cc1F>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)OC)c(F)c1 -US08466295B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(Cc1ccccc1)c1cc(Br)cs1>>CC(C)(C)OC(=O)NC(Cc1ccccc1)c1cc(Br)cs1 -US20110152245A1,6,CC(C)(C)OC(=O)N1CC[C@H](c2ccc(NC(=O)c3ccc(OCC(F)(F)F)nc3)cc2)C1>>O=C(Nc1ccc([C@H]2CCNC2)cc1)c1ccc(OCC(F)(F)F)nc1 -US08785478B2,3,O=Cc1cc(Br)c([N+](=O)[O-])cc1[N+](=O)[O-].OB(O)C1CC1>>O=Cc1cc(C2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-] -US20150087639A1,1,CCCCNCCCC.O=[N+]([O-])c1ccc(F)c(F)c1>>CCCCN(CCCC)c1ccc([N+](=O)[O-])cc1F -US20100249124A1,1,CC(c1ccc(O)cc1Cl)C(O)(c1ccc2oc(=O)n(C)c2c1)C(F)(F)F.COC(=O)c1cnc(Cl)cc1Cl>>COC(=O)c1cnc(Oc2ccc(C(C)C(O)(c3ccc4oc(=O)n(C)c4c3)C(F)(F)F)c(Cl)c2)cc1Cl -US20130131035A1,1,CNC(=O)c1cccc(N)c1.Clc1cc(Cl)ncn1>>CNC(=O)c1cccc(Nc2cc(Cl)ncn2)c1 -US20120121508A1,3,C=CCN1C(=O)C2(CCCC2)N(C(=O)OC(C)(C)C)C[C@@]1(C)c1cc(F)cc(F)c1.C[Si](C)(C)CCOCN1C(=O)C2(Cc3ccc(Br)cc3C2)c2cccnc21>>CC(C)(C)OC(=O)N1C[C@@](C)(c2cc(F)cc(F)c2)N(C/C=C/c2ccc3c(c2)CC2(C3)C(=O)N(COCC[Si](C)(C)C)c3ncccc32)C(=O)C12CCCC2 -US07932390B2,1,CCOC(=O)c1cnc(Cl)c2c(CBr)csc12.COc1ccc(Cn2nnc(-c3cccc(O)c3)n2)cc1>>CCOC(=O)c1cnc(Cl)c2c(COc3cccc(-c4nnn(Cc5ccc(OC)cc5)n4)c3)csc12 -US07960369B2,6,CC(C)(C)OC(=O)CCc1ccc(OCc2cccc(-c3ccccc3C(=O)O)c2)cc1>>O=C(O)CCc1ccc(OCc2cccc(-c3ccccc3C(=O)O)c2)cc1 -US04236005,6,CCOC(=O)c1ncn2c(-c3cccc(C(F)(F)F)c3)ccnc12>>O=C(O)c1ncn2c(-c3cccc(C(F)(F)F)c3)ccnc12 -US20100324052A1,1,CCN(CCc1ccc(Cl)c(C=O)c1)C(=O)OC(C)(C)C.NC1CC1>>CCN(CCc1ccc(Cl)c(CNC2CC2)c1)C(=O)OC(C)(C)C -US20060167016A1,4,NCc1ccccc1.O=S(=O)(c1ccccc1)N1CC(CI)OC(CI)C1>>O=S(=O)(c1ccccc1)N1CC2CN(Cc3ccccc3)CC(C1)O2 -US07964622B2,2,CC(=O)O.COc1ccc(C(=O)CCl)c(N)c1>>COc1ccc(C(=O)CCl)c(NC(C)=O)c1 -US20130324579A1,4,COc1ccc(N)c(NCCO)c1.O=CO>>COc1ccc2ncn(CCO)c2c1 -US06710060B2,3,CCOc1ccc(N(C)C(C)=O)cc1.O=C1CCN(Cc2ccccc2)CC1>>CCOc1ccc(N(C)C(=O)CC2(O)CCN(Cc3ccccc3)CC2)cc1 -US20150238473A1,5,COC(=O)c1ccc(C=O)cc1.SCCCS>>COC(=O)c1ccc(C2SCCCS2)cc1 -US20090286778A1,2,Cc1ccccc1S(=O)(=O)Cl.O=C(CC1CCNCC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2>>Cc1ccccc1S(=O)(=O)N1CCC(CC(=O)Nc2ccc3cc2CCc2cncc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US20040157898A1,6,CCO[C@@H](Cc1c(C)cc(OCc2nc(C(C)(C)C)oc2C)cc1C)C(=O)OC>>CCO[C@@H](Cc1c(C)cc(OCc2nc(C(C)(C)C)oc2C)cc1C)C(=O)O -US20090286768A1,6,CC(C)(C)OC(=O)N1CC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)C1>>Nc1nccn2c(C3CNC3)nc(-c3ccc(Oc4ccccc4)cc3)c12 -US04518597,1,CC(C)C1OC(=O)Nc2ccc(OCCCCl)cc21.Sc1ccc(Cl)c(Cl)c1>>CC(C)C1OC(=O)Nc2ccc(OCCCSc3ccc(Cl)c(Cl)c3)cc21 -US20150158883A1,2,CC(C)c1nc(CCN)cs1.O=C(O)c1cc(Cl)ccc1O>>CC(C)c1nc(CCNC(=O)c2cc(Cl)ccc2O)cs1 -US20150023913A1,1,BrCc1ccccc1.CC(CO)(CO)C(=O)O>>CC(CO)(CO)C(=O)OCc1ccccc1 -US20080287430A1,7,CCOC(=O)c1ccc(Cc2cc(Cl)ccc2OCC(C)C)o1>>CC(C)COc1ccc(Cl)cc1Cc1ccc(CO)o1 -US20110082181A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(F)(F)CCCc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(F)(F)CCCc4ccccc4)cc3)cc2)CC1 -US07435815B2,1,CCN.CCNC(=O)c1cccc(Br)n1>>CCNC(=O)c1cccc(NCC)n1 -US20120226037A1,1,CC(=O)c1cc(C)c(Oc2nc(Cl)nc3ccn(Cc4ccccc4)c23)c(C)c1.N#Cc1ccc(N)cc1>>CC(=O)c1cc(C)c(Oc2nc(Nc3ccc(C#N)cc3)nc3ccn(Cc4ccccc4)c23)c(C)c1 -US20130090340A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1c(-c2cccc(C#N)c2)c(Cl)n2c1CNCC2>>COC(=O)c1c(-c2cccc(C#N)c2)c(Cl)n2c1CN(C(=O)OC(C)(C)C)CC2 -US08394795B2,8,OC(c1n[nH]c2ncccc12)C1CC1>>O=C(c1n[nH]c2ncccc12)C1CC1 -US08853290B2,1,O=c1c2ccccc2sc2ccc(CBr)cc12.OCCN(CCO)CCO>>O=c1c2ccccc2sc2ccc(C[N+](CCO)(CCO)CCO)cc12 -US20030069297A1,3,Cc1[nH]c(C=O)c(C)c1C(=O)NCCN(C(C)C)C(C)C.O=C1Cc2c(cccc2-c2ccc(Br)cc2)N1>>Cc1[nH]c(C=C2C(=O)Nc3cccc(-c4ccc(Br)cc4)c32)c(C)c1C(=O)NCCN(C(C)C)C(C)C -US20100113422A1,3,CB1OB(C)OB(C)O1.Clc1nc(Cc2ccccc2)nc2c1CCN(Cc1ccccc1)CC2>>Cc1nc(Cc2ccccc2)nc2c1CCN(Cc1ccccc1)CC2 -US20120202806A1,9,COc1cnc(-c2ccccn2)nc1Cl.N>>COc1cnc(-c2ccccn2)nc1N -US20140058125A1,3,C#Cc1ccc(CCC(=O)OC)c(F)c1.Fc1ccc(C(F)F)c(Br)c1>>COC(=O)CCc1ccc(C#Cc2cc(F)ccc2C(F)F)cc1F -US05310743,2,N[C@H]1CCN(C(=O)c2cc(Cl)cc(Cl)c2)[C@H](Cc2ccccc2)C1.O=C(O)c1cc2ccccc2[nH]1>>O=C(N[C@H]1CCN(C(=O)c2cc(Cl)cc(Cl)c2)[C@H](Cc2ccccc2)C1)c1cc2ccccc2[nH]1 -US04952574,2,CCOc1ccc(OCC(F)(F)F)cc1C(=O)O.NCc1ccccn1>>CCOc1ccc(OCC(F)(F)F)cc1C(=O)NCc1ccccn1 -US08389513B2,2,CC1(C)OC(N)=N[C@](C)(c2cc(N)ccc2F)C1(F)F.O=C(O)c1ncc(Cl)cc1Cl>>CC1(C)OC(N)=N[C@](C)(c2cc(NC(=O)c3ncc(Cl)cc3Cl)ccc2F)C1(F)F -US07935688B2,3,CCC(CC)(c1ccc(C#CC2(O[Si](C)(C)C)CCOCC2)c(C)c1)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1.COC(=O)Cc1ccc(Br)cc1>>CCC(CC)(c1ccc(C#CC2(O[Si](C)(C)C)CCOCC2)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)cc2)c(C)c1 -US20060194716A1,1,CC(O)S.CCCCCCCCCCBr>>CCCCCCCCCCSC(C)O -US05274135,2,CS(=O)(=O)Cl.Oc1cccc2c1CC2>>CS(=O)(=O)Oc1cccc2c1CC2 -US06924292B2,6,COC(=O)COc1cc2c(c3c1OC(C)(C)C3)C(c1ccccc1)=NC(C)(C)C2>>CC1(C)Cc2cc(OCC(=O)O)c3c(c2C(c2ccccc2)=N1)CC(C)(C)O3 -US06723722B1,1,CC(C)(C)OC(=O)CNS(=O)(=O)c1ccc2cc(Cl)ccc2c1.COC(=O)/C=C/CBr>>COC(=O)C=CCN(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc2cc(Cl)ccc2c1 -US20120101083A1,6,CCOC(=O)c1cnc(NC(C)C)c(C#N)c1>>CC(C)Nc1ncc(C(=O)O)cc1C#N -US07446103B2,1,C1CCNCC1.CCOC(=O)c1ccc(OCCCCl)cc1>>CCOC(=O)c1ccc(OCCCN2CCCCC2)cc1 -US20090143354A1,1,CCOC(=O)CN1CCNCC1.O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(Cl)ccc12>>CCOC(=O)CN1CCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)CC1 -US20040235822A1,1,O=[N+]([O-])c1ccc(CCCBr)cc1.c1c[nH]cn1>>O=[N+]([O-])c1ccc(CCCn2ccnc2)cc1 -US20050124562A1,1,CC(C)(C)OC(=O)Nc1cccc(O)c1.CCCCO>>CCCCOc1cccc(NC(=O)OC(C)(C)C)c1 -US20100160308A1,1,CN1CCNCC1.NC(=O)c1sc(Nc2cc(C=O)ccc2[N+](=O)[O-])nc1-c1cccc(C(F)(F)F)c1>>CN1CCN(Cc2ccc([N+](=O)[O-])c(Nc3nc(-c4cccc(C(F)(F)F)c4)c(C(N)=O)s3)c2)CC1 -US06716989B2,9,Cc1c(Br)ccc(Br)c1C=O.NO>>Cc1c(Br)ccc(Br)c1C=NO -US08722702B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(C)Cc1c[nH]c2ncccc12>>CN(C)Cc1cn(C(=O)OC(C)(C)C)c2ncccc12 -US20080261941A1,6,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccc(Br)cn3)c2)CC1>>Brc1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1 -US04587342,8,COc1cc(Cc2cnc(N)nc2N)c2c(c1OC)OCC=C2.O=C(OO)c1cccc(Cl)c1>>COc1cc(Cc2c[n+]([O-])c(N)nc2N)c2c(c1OC)OCC=C2 -US20050010048A1,6,COc1ccc(C)c2cccnc12>>Cc1ccc(O)c2ncccc12 -US05420287,3,CSc1ccc(C2=C(Br)CCC2)cc1.N#Cc1ccc(B(O)O)cc1>>CSc1ccc(C2=C(c3ccc(C#N)cc3)CCC2)cc1 -US08552039B2,6,COC(=O)CCCCc1nc(-c2ccccc2OC)no1>>COc1ccccc1-c1noc(CCCCC(=O)O)n1 -US20060019945A1,2,CC(C)[C@@H](C(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](C(=O)O)C3)c1ccccn1.NCc1c[nH]nn1>>CC(C)[C@@H](C(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](C(=O)NCc1c[nH]nn1)C3)c1ccccn1 -US06630472B1,7,COc1ccccc1CCN1C(=O)C2CCCC(C1=O)N2C(=O)OCc1ccccc1>>COc1ccccc1CCN1C(=O)C2CCCC(C1O)N2C(=O)OCc1ccccc1 -US06943183B2,2,C[C@H](O)CN.O=C(O)c1cccc(S(=O)(=O)Cc2c(O[C@H](Cn3ccnc3)c3ccccc3)ccc3c2CCCC3=O)c1>>C[C@H](O)CNC(=O)c1cccc(S(=O)(=O)Cc2c(O[C@H](Cn3ccnc3)c3ccccc3)ccc3c2CCCC3=O)c1 -US20090118280A1,2,O=C(O)Cc1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1.c1ccc(C2CCCN2)cc1>>O=C(Cc1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1)N1CCCC1c1ccccc1 -US20130158269A1,7,CCn1c(-c2ccc(C)cc2)cc2cc([N+](=O)[O-])cnc21>>CCn1c(-c2ccc(C)cc2)cc2cc(N)cnc21 -US05578732,8,Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2[nH]1.OO>>Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1 -US20090099161A1,7,COCCc1nc2cnc3ccc(C=CC(=O)N(C)C)cc3c2n1CCCN1CCCC1=O>>COCCc1nc2cnc3ccc(CCC(=O)N(C)C)cc3c2n1CCCN1CCCC1=O -US20020032187A1,2,COC(=O)CC1Cc2ccc(C(=O)O)cc2CN(C)C1=O.NCc1nc2ccccc2[nH]1>>COC(=O)CC1Cc2ccc(C(=O)NCc3nc4ccccc4[nH]3)cc2CN(C)C1=O -US20040224959A1,1,BrCCC(c1ccccc1)c1ccccc1.O=c1c2cc(N3CCNCC3)ccc2cnn1Cc1ccccc1>>O=c1c2cc(N3CCN(CCC(c4ccccc4)c4ccccc4)CC3)ccc2cnn1Cc1ccccc1 -US05399290,1,C=CCCc1ccc(CCc2ccc(O)cc2)cc1.CC[C@H](C)COc1ccc(C(=O)O)cc1F>>C=CCCc1ccc(CCc2ccc(OC(=O)c3ccc(OC[C@@H](C)CC)c(F)c3)cc2)cc1 -US20090047223A1,2,CCOC(=O)C=CC(=O)Cl.OC/C=C/c1ccccc1>>CCOC(=O)/C=C/C(=O)OCC=Cc1ccccc1 -US20150225390A1,2,COC1CN(C(=O)OC(C)(C)C)CCC1NC1CC1.O=C(O)c1ccc(-c2cnco2)cc1>>COC1CN(C(=O)OC(C)(C)C)CCC1N(C(=O)c1ccc(-c2cnco2)cc1)C1CC1 -US20070270421A1,2,Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ccn1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ccn1)Oc1ccccc1 -US20060235024A1,1,C#CC(C)(C)Cl.CCOC(=O)N1CCNCC1>>C#CC(C)(C)N1CCN(C(=O)OCC)CC1 -US05886044,2,COC(=O)c1ccc(N)c(O)c1.O=C=Nc1ccccc1>>COC(=O)c1ccc(NC(=O)Nc2ccccc2)c(O)c1 -US07105671B2,6,CNC(=O)NC(=O)C(CC1CCCC1OC1CCCCO1)c1ccc(Cl)c(Cl)c1>>CNC(=O)NC(=O)C(CC1CCCC1O)c1ccc(Cl)c(Cl)c1 -US20120115862A1,6,COc1ccc2c(c1)C(=O)c1ccc(Nc3ccccc3)cc1CC2>>O=C1c2ccc(Nc3ccccc3)cc2CCc2ccc(O)cc21 -US20120065195A1,3,CC1(Cc2ccc(Br)cc2)CC(=O)c2cc(Br)ccc2C1.OB(O)c1cncc(Cl)c1>>CC1(Cc2ccc(Br)cc2)CC(=O)c2cc(-c3cncc(Cl)c3)ccc2C1 -US20110144074A1,8,CCCC(CC(=O)n1c2ccccc2c2ccccc21)C(=O)NC(CC(=O)OC(C)(C)C)C(O)CF>>CCCC(CC(=O)n1c2ccccc2c2ccccc21)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)CF -US20080167310A1,1,CC(C)(C)OC(=O)CCc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1CBr.Oc1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)CCc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1COc1ccc(C(F)(F)F)cc1 -US07727997B2,2,CCCN(CCC)c1nccc2ccc(C(=O)O)cc12.CCc1cccc(CNC[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)c1>>CCCN(CCC)c1nccc2ccc(C(=O)N[C@@H](Cc3cc(F)cc(F)c3)[C@H](O)CNCc3cccc(CC)c3)cc12 -US20110319393A1,2,FC(F)(F)c1cc(NC2CCNCC2)ccc1Cl.O=C(O)CCCN1CCN(c2ccc(C(F)(F)F)cc2)CC1>>O=C(CCCN1CCN(c2ccc(C(F)(F)F)cc2)CC1)N1CCC(Nc2ccc(Cl)c(C(F)(F)F)c2)CC1 -US20130190330A1,4,C#CCn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O.[N-]=[N+]=Nc1cccc(Cl)c1Cl>>O=c1n(Cc2cn(-c3cccc(Cl)c3Cl)nn2)nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F -US07994167B2,7,CS(=O)(=O)Nc1ccc(C#N)cc1F>>CS(=O)(=O)Nc1ccc(CN)cc1F -US06537948B1,7,COC(=O)COc1ccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2[N+](=O)[O-])cn1>>COC(=O)COc1ccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2N)cn1 -US04241072,2,CN(C)C(=O)Cl.CN(C)CCNc1nccs1>>CN(C)CCN(C(=O)N(C)C)c1nccs1 -US05693635,2,Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1.O=C(Cl)c1ccc(F)cc1F>>O=C(Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1)c1ccc(F)cc1F -US05250699,1,CC(=O)CCl.O=C1N(Cc2ccccc2)C(O)C(CS)N1Cc1ccccc1>>CC(=O)CSCC1C(O)N(Cc2ccccc2)C(=O)N1Cc1ccccc1 -US05364767,6,CC(=O)Nc1cc(Cl)ccc1C(=O)O>>Nc1cc(Cl)ccc1C(=O)O -US20100168080A1,1,COC(=O)c1cc(Cl)c([N+](=O)[O-])cc1O.OCCCBr>>COC(=O)c1cc(Cl)c([N+](=O)[O-])cc1OCCCBr -US05958934,1,COc1ccc2c(c1)CCCN2.Cc1cc(Cl)nc(N)n1>>COc1ccc2c(c1)CCCN2c1cc(C)nc(N)n1 -US07902367B2,1,CC(C)(C)OC(=O)N1CCCC(O)C1.Cc1nc(-c2ccc(Cl)cc2)sc1CCl>>Cc1nc(-c2ccc(Cl)cc2)sc1COC1CCCN(C(=O)OC(C)(C)C)C1 -US20040204455A1,7,N#Cc1ccc2[nH]ccc2c1>>NCc1ccc2[nH]ccc2c1 -US20150274666A1,1,COc1cc(F)ccc1-c1cc(Cl)ncc1F.Nc1cc(CO)ccn1>>COc1cc(F)ccc1-c1cc(Nc2cc(CO)ccn2)ncc1F -US20070106076A1,7,C[C@@H]1CNC(=O)c2cc3ccc(C(F)(F)F)cc3n21>>C[C@@H]1CNCc2cc3ccc(C(F)(F)F)cc3n21 -US07468391B2,3,C#Cc1cc(OC)c2c(c1)C(C)(C)CCC2N(C)C1CC1.COC(=O)Cc1ccc(I)cc1F>>COC(=O)Cc1ccc(C#Cc2cc(OC)c3c(c2)C(C)(C)CCC3N(C)C2CC2)cc1F -US07560569B2,2,C[C@H](N)c1ccccc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CN(C(=O)OCc1ccccc1)C12CCC(C(=O)O)(CC1)CC2>>C[C@H](NC(=O)C12CCC(N(CC(=O)N3C[C@@H](F)C[C@H]3C#N)C(=O)OCc3ccccc3)(CC1)CC2)c1ccccc1 -US08058045B2,6,COc1nc(Nc2cc(NCC3CCN(C(=O)OC(C)(C)C)CC3)ncn2)cnc1C#N>>COc1nc(Nc2cc(NCC3CCNCC3)ncn2)cnc1C#N -US07902373B2,3,O=C(O)c1ccc(Cl)nc1.OB(O)c1cccc(F)c1>>O=C(O)c1ccc(-c2cccc(F)c2)nc1 -US06664271B1,2,CCN.O=C(Cl)C1CCCN(C(=O)Cc2cccs2)C1>>CCNC(=O)C1CCCN(C(=O)Cc2cccs2)C1 -US20090118200A1,1,CO.O=C(O)CCc1nc2ccccc2[nH]1>>Cn1c(CCC(=O)O)nc2ccccc21 -US08546359B2,6,COC(=O)CCC(C)(c1ccc2cc(O[C@@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1)[N+](=O)[O-]>>CC(CCC(=O)O)(c1ccc2cc(O[C@@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1)[N+](=O)[O-] -US20100168161A1,1,BrCc1cccc(Br)c1.OCC(F)(F)c1ccccc1>>FC(F)(COCc1cccc(Br)c1)c1ccccc1 -US20150225427A1,1,COc1cc(N)cc(C(=O)O)c1.Cc1ccc(-n2nc([Si](C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc1>>COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc([Si](C)(C)C)nn4-c4ccc(C)cc4)c4ccccc34)n2)cc(C(=O)O)c1 -US20040214817A1,2,Nc1nc(Nc2cccnc2)n[nH]1.O=C=Nc1ccccc1>>Nc1nc(Nc2cccnc2)nn1C(=O)Nc1ccccc1 -US20010006969A1,1,C=CCN.CCc1csc2c(NC(C)(C)C)nc(Cl)nc12>>C=CCNc1nc(NC(C)(C)C)c2scc(CC)c2n1 -US20120157433A1,6,COc1ccc(F)cc1-c1cc(NC(=O)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)ncc1Cl>>COc1ccc(F)cc1-c1cc(NC(=O)[C@@H]2CCCNC2)ncc1Cl -US20140113877A1,6,COc1ccc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccc(F)cc4OC)cc32)cc1F>>COc1ccc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccc(F)cc4OC)cc32)cc1F -US20080058335A1,6,COCCOc1ccccc1C(=O)OC>>COCCOc1ccccc1C(=O)O -US04528298,8,COc1ccc(-c2nc(Sc3ccccc3)[nH]c2-c2ccc(OC)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nc(S(=O)c3ccccc3)[nH]c2-c2ccc(OC)cc2)cc1 -US20120015988A1,6,CC(C)(CO[Si](C)(C)C(C)(C)C)c1cc(-c2nnc(C(C)(C)S(=O)(=O)c3ccc(F)cc3)o2)on1>>CC(C)(CO)c1cc(-c2nnc(C(C)(C)S(=O)(=O)c3ccc(F)cc3)o2)on1 -US20130023522A1,3,C#C[Si](C)(C)C.Cc1ccccc1N1CCN(c2ccc(C(=O)NCCCN3CCCC3=O)cc2NC(=O)c2ccc(Br)o2)CC1>>C#Cc1ccc(C(=O)Nc2cc(C(=O)NCCCN3CCCC3=O)ccc2N2CCN(c3ccccc3C)CC2)o1 -US20080318925A1,3,COc1ncc(B(O)O)c(OC)n1.Nc1c(C(=O)NC2CCC2)nnc2c(Br)c(F)ccc12>>COc1ncc(-c2c(F)ccc3c(N)c(C(=O)NC4CCC4)nnc23)c(OC)n1 -US06933311B2,2,CC(C)(N=C=O)c1ccc(Cl)cc1.Nc1cccc2cnccc12>>CC(C)(NC(=O)Nc1cccc2cnccc12)c1ccc(Cl)cc1 -US04419352,2,CC(=O)O.COc1ccc(N)c(O)c1C(C)=O>>COc1ccc(NC(C)=O)c(O)c1C(C)=O -US20070060607A1,1,ClCc1ccc(Cl)cc1.Oc1ccc(Cl)c(O)c1>>Oc1cc(OCc2ccc(Cl)cc2)ccc1Cl -US04692552,6,CCCCCCCCCCCCCCCCCC(=O)c1cc(C(=O)OCC)ccc1O>>CCCCCCCCCCCCCCCCCC(=O)c1cc(C(=O)O)ccc1O -US20110207704A1,1,CC(C)Oc1ccc(-c2noc(-c3ccc(F)cc3)n2)cc1Cl.N[C@H]1CC[C@@H](C(=O)O)C1>>CC(C)Oc1ccc(-c2noc(-c3ccc(N[C@H]4CC[C@@H](C(=O)O)C4)cc3)n2)cc1Cl -US07262196B2,2,CSc1ccc(/C(=C\C2CCCC2)C(=O)O)nc1.Nc1nccs1>>CSc1ccc(/C(=C\C2CCCC2)C(=O)Nc2nccs2)nc1 -US20050107347A1,6,COC(=O)CCc1cc(Br)c(Oc2cc(CCc3ccccc3)c(O)c(C(C)C)c2)c(Br)c1>>CC(C)c1cc(Oc2c(Br)cc(CCC(=O)O)cc2Br)cc(CCc2ccccc2)c1O -US20090197877A1,7,O=[N+]([O-])c1cc(I)cc(I)c1>>Nc1cc(I)cc(I)c1 -US04956005,2,NC1CC1.NS(=O)(=O)c1ccccc1S(=O)(=O)Cl>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC1CC1 -US07312214B2,7,COC(=O)C(C)(C)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1>>CC(C)(CO)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 -US20150038492A1,6,CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O>>NC(=O)[C@H](N)Cc1c[nH]c2ccccc12 -US09034877B2,1,C1CNCCN1.COc1ccc(COc2cccc3c(Cl)ccnc23)cc1>>COc1ccc(COc2cccc3c(N4CCNCC4)ccnc23)cc1 -US20120309796A1,3,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1ccc(Br)cn1.OB(O)c1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1ccc(-c2cccc(C(F)(F)F)c2)cn1 -US07179823B1,1,CCOC(=O)CCc1c[nH]nc1-c1ccccc1.Cc1oc(-c2ccccc2)nc1COc1ccc(CCOS(C)(=O)=O)cc1>>CCOC(=O)CCc1cn(CCc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)nc1-c1ccccc1 -US20010009916A1,2,COC(=O)Cl.N[C@H](Cc1ccccc1)C(=O)O>>COC(=O)N[C@H](Cc1ccccc1)C(=O)O -US20090062536A1,1,CI.COc1nc(OC)nc(C(=O)c2cccc(Br)c2NS(=O)(=O)C(F)F)n1>>COc1nc(OC)nc(C(=O)c2cccc(Br)c2N(C)S(=O)(=O)C(F)F)n1 -US20030216410A1,2,CCN(CC)CCN.Cc1cc(C(=O)O)c(C=O)[nH]1>>CCN(CC)CCNC(=O)c1cc(C)[nH]c1C=O -US20090181945A1,2,C=CCC(=O)O.C=C[C@@H]1CCC[C@H](c2ccc(F)cc2)N1>>C=CCC(=O)N1[C@H](C=C)CCC[C@@H]1c1ccc(F)cc1 -US20030092715A1,2,CN(C)CCC(O)c1ccc(-c2ccncc2)cc1.O=C=Nc1cc(Cl)cc(Cl)c1>>CN(C)CCC(OC(=O)Nc1cc(Cl)cc(Cl)c1)c1ccc(-c2ccncc2)cc1 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1ccc2cc[nH]c2c1>>FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc5cc[nH]c5c4)c3)c(Cc3ccccc3)cnc12 -US20100160371A1,2,CC(C)(C)OC(=O)NCC(=O)O.Cc1ccc(NC(=O)Nc2cc(C(C)(C)C)sc2CN)cc1>>Cc1ccc(NC(=O)Nc2cc(C(C)(C)C)sc2CNC(=O)CNC(=O)OC(C)(C)C)cc1 -US20150080365A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCOc1cc(C)nc(Br)c1>>CCOc1cc(C)nc(N2CCN(C(=O)OC(C)(C)C)CC2)c1 -US05541182,2,Cc1cccc(N=C=O)c1.NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)c2cccnc2)C1=O>>Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(=O)c3cccnc3)C2=O)c1 -US08987307B2,3,CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1Br.COc1cccc(F)c1B(O)O>>COc1cccc(F)c1-c1ccncc1N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US06645990B2,1,NCCO.O=C1CCN(Cc2cccc(NC(=O)Nc3csc(-c4ccncc4)n3)n2)CC1>>O=C(Nc1cccc(CN2CCC(NCCO)CC2)n1)Nc1csc(-c2ccncc2)n1 -US20110136792A1,1,CCOC(=O)c1csc(CBr)n1.Oc1ccc(-c2cc(F)c(F)cc2F)cc1>>CCOC(=O)c1csc(COc2ccc(-c3cc(F)c(F)cc3F)cc2)n1 -US04906636,3,O=C(Cl)c1ccccc1.Oc1c(Cc2ccccc2)ccc2ccccc12>>O=C(c1ccccc1)c1cc(Cc2ccccc2)c(O)c2ccccc12 -US08084614B2,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(Cl)cc1OC.N#Cc1cc(C(F)(F)F)ncc1Br>>COC(=O)c1cc(-c2cnc(C(F)(F)F)cc2C#N)c(Cl)cc1OC -US20110098301A1,7,O=[N+]([O-])c1ccc(Cc2ccc(F)cc2)cc1>>Nc1ccc(Cc2ccc(F)cc2)cc1 -US06552054B1,2,CCCc1c2c(c(O)c3c(=O)cc(C(=O)O)oc13)CCCC2.Nc1ccc(CC2SC(=O)NC2=O)cc1>>CCCc1c2c(c(O)c3c(=O)cc(C(=O)Nc4ccc(CC5SC(=O)NC5=O)cc4)oc13)CCCC2 -US06372740B1,1,CCN(C(=O)CBr)c1ccccc1.Cn1c(=O)[nH]c2cnc(-c3ccccc3)nc21>>CCN(C(=O)Cn1c(=O)n(C)c2nc(-c3ccccc3)ncc21)c1ccccc1 -US08309546B2,1,CN(C)C1CCNC1.Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2nc(Cl)n(CC3CC3)c2n1>>Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2nc(N3CCC(N(C)C)C3)n(CC3CC3)c2n1 -US20130225524A1,6,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4cnc(OC)nc4OC)ccc23)c1>>COc1ncc(-c2ccc3c(Nc4cccc(C(=O)O)c4)c(C(N)=O)cnc3c2)c(OC)n1 -US05015260,5,COc1cc(C)c(O)cc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cc(C)c(O)cc1NC(=O)C(F)(F)F -US08153652B2,6,CCn1cc(CN(C)C(=O)OCc2ccccc2)c2ccccc21>>CCn1cc(CNC)c2ccccc21 -US20130023532A1,1,CNc1n[nH]c2ccc(F)cc12.Clc1ccnc(Cl)n1>>CN(c1ccnc(Cl)n1)c1n[nH]c2ccc(F)cc12 -US04517187,7,CCCCCC(=O)N1CCN2C[C@@H](c3ccccc3)c3ccccc3[C@@H]2C1>>CCCCCCN1CCN2C[C@@H](c3ccccc3)c3ccccc3[C@@H]2C1 -US05968930,2,Cc1c(F)cccc1C(=O)Cl.Nc1ccc(C(=O)N2CCc3cccn3-c3ccccc32)c(Cl)c1>>Cc1c(F)cccc1C(=O)Nc1ccc(C(=O)N2CCc3cccn3-c3ccccc32)c(Cl)c1 -US20080090794A1,3,Brc1ccccn1.CON(C)C(=O)C(c1ccccc1)N1CCOCC1>>O=C(c1ccccn1)C(c1ccccc1)N1CCOCC1 -US08067408B2,2,CNCc1cccc(Br)c1.O=C(O)c1cccc(S(=O)(=O)Cl)c1>>CN(Cc1cccc(Br)c1)S(=O)(=O)c1cccc(C(=O)O)c1 -US05618819,3,BrCc1ccccc1.Cn1c(=O)oc2cc(Br)cnc21>>Cn1c(=O)oc2cc(Cc3ccccc3)cnc21 -US20040063691A1,6,Cc1c(C(=O)OC(C)(C)C)nc(-c2ccccc2Cl)n1-c1ccc([N+](=O)[O-])cc1>>Cc1c(C(=O)O)nc(-c2ccccc2Cl)n1-c1ccc([N+](=O)[O-])cc1 -US20140275172A1,6,CCOC(=O)CCc1ccc(OCc2cc(C#N)cc3cc(CC)oc23)c(C)c1C>>CCc1cc2cc(C#N)cc(COc3ccc(CCC(=O)O)c(C)c3C)c2o1 -US08148572B2,1,CCS(=O)(=O)c1ccc(Cl)c(C#N)c1.O=C(O)Cc1cc(O)cc(C(F)(F)F)c1>>CCS(=O)(=O)c1ccc(Oc2cc(CC(=O)O)cc(C(F)(F)F)c2)c(C#N)c1 -US08501758B2,7,COc1cc(Br)cc([N+](=O)[O-])c1C>>COc1cc(Br)cc(N)c1C -US20090197877A1,2,CCOC(=O)Cl.Nc1nc2cc(-c3cccnc3)cc(-c3ccccn3)c2s1>>CCOC(=O)Nc1nc2cc(-c3cccnc3)cc(-c3ccccn3)c2s1 -US20090298836A1,6,CC(C)(C)OC(=O)N(C[C@@H](N)Cc1ccc(C(F)(F)F)cc1)c1nnc(-c2ccc3ncncc3c2)s1>>N[C@H](CNc1nnc(-c2ccc3ncncc3c2)s1)Cc1ccc(C(F)(F)F)cc1 -US08344135B2,2,CC(=O)Nc1nc2cnc(N(c3cccc(N)c3)C3CC3)nc2s1.O=C(O)c1cccc(OC(F)(F)F)c1>>CC(=O)Nc1nc2cnc(N(c3cccc(NC(=O)c4cccc(OC(F)(F)F)c4)c3)C3CC3)nc2s1 -US06514975B1,4,C[Si](C)(C)N=[N+]=[N-].N#Cc1ccc(C=O)cc1>>O=Cc1ccc(-c2nnn[nH]2)cc1 -US04312870,6,COc1ccc(-n2nc3c4ccccc4[nH]cc-3c2=O)cc1>>O=c1c2c[nH]c3ccccc3c-2nn1-c1ccc(O)cc1 -US08691804B2,1,FC(F)(F)Oc1ccc(I)cc1.O=C(N1CCCN(C2CCC2)CC1)N1CC(O)C1>>O=C(N1CCCN(C2CCC2)CC1)N1CC(Oc2ccc(OC(F)(F)F)cc2)C1 -US20090233937A1,2,N#CC1(C(=O)O)CC1.NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21>>N#CC1(C(=O)NCCn2ccc3ncnc(Nc4ccc(Oc5cccc6sncc56)c(Cl)c4)c32)CC1 -US20040132727A1,7,COc1ccc(OCC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1>>COc1ccc(OCCNc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1 -US20080269220A1,6,COC(=O)CCc1ccc(NCc2ccc(Cn3nc(-c4ccccc4)cc3-c3ccccc3)cc2)cc1>>O=C(O)CCc1ccc(NCc2ccc(Cn3nc(-c4ccccc4)cc3-c3ccccc3)cc2)cc1 -US08846972B2,9,CC(CNC(=O)OC(C)(C)C)N=[N+]=[N-]>>CC(N)CNC(=O)OC(C)(C)C -US20090286778A1,2,O=C(Cl)Cc1ccccc1.O=C(Nc1ccc2cc1CCc1cccc(c1)Nc1ncc(Cl)c(n1)N2)C1CCNCC1>>O=C(Nc1ccc2cc1CCc1cccc(c1)Nc1ncc(Cl)c(n1)N2)C1CCN(C(=O)Cc2ccccc2)CC1 -US20070197794A1,9,CO/N=C1/C[C@@H](C(N)=O)N(C(=O)c2ccc(-c3ccccc3)cc2)C1>>CO/N=C1/C[C@@H](C#N)N(C(=O)c2ccc(-c3ccccc3)cc2)C1 -US08710224B2,6,CCN1CCN(C(=O)OCc2ccccc2)C(CN2CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)C1>>CCN1CCNC(CN2CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)C1 -US20150105373A1,6,CC(C)(C)OC(=O)NC(CN1CCCC1)c1ccc(OC(F)(F)F)cc1>>NC(CN1CCCC1)c1ccc(OC(F)(F)F)cc1 -US20130345199A1,1,CC(C)(C)NC(=O)C1CCNCC1.O=Cc1cc(Br)cs1>>CC(C)(C)NC(=O)C1CCN(Cc2cc(Br)cs2)CC1 -US08324216B2,2,Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O.c1cnc(N2CCNCC2)nc1>>Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ncccn2)CC1 -US20130030171A1,1,CN1CCNCC1.O=[N+]([O-])c1cccc(CCl)c1>>CN1CCN(Cc2cccc([N+](=O)[O-])c2)CC1 -US20130253186A1,1,Clc1ccncc1Br.OC1CN(c2ccc3ccccc3n2)C1>>Brc1cnccc1OC1CN(c2ccc3ccccc3n2)C1 -US08173650B2,1,CC(C)(C)OC(=O)N1CC(=O)C1.F[C@H]1CCNC1>>CC(C)(C)OC(=O)N1CC(N2CC[C@H](F)C2)C1 -US20100160323A1,1,COC(=O)c1ccc(Br)cc1.Nc1ccccc1>>COC(=O)c1ccc(Nc2ccccc2)cc1 -US20140005168A1,1,CC(C)(C)OC(=O)N1CCCN(c2cncc(Br)n2)CC1.Clc1cc2[nH]ncc2cn1>>CC(C)(C)OC(=O)N1CCCN(c2cncc(-n3ncc4cnc(Cl)cc43)n2)CC1 -US20100041711A1,9,C[C@@H]1CC[C@@H](N(CCOCc2ccccc2Cl)C(=O)Nc2ncc(SCC(C)(C)C(=O)O)s2)CC1>>C[C@@H]1CC[C@@H](N(CCOCc2ccccc2)C(=O)Nc2ncc(SCC(C)(C)C(=O)O)s2)CC1 -US20150175623A1,3,CC1(C)OB(c2cccc(F)c2F)OC1(C)C.Clc1ncnc2sc(I)c(Br)c12>>Fc1cccc(-c2sc3ncnc(Cl)c3c2Br)c1F -US20050054633A1,2,CC(=O)N1C[C@H](N)C(=O)N(C(C)C)c2ccccc21.CC(C(=O)O)C(=O)NCC(F)(F)C(F)(F)F>>CC(=O)N1C[C@H](NC(=O)C(C)C(=O)NCC(F)(F)C(F)(F)F)C(=O)N(C(C)C)c2ccccc21 -US20150232454A1,1,COCn1ncc(Cl)c(Cl)c1=O.C[O-]>>COCn1ncc(Cl)c(OC)c1=O -US04028344,2,CC(C)(C)N=NC1(N=C=S)CCCCC1.CC(C)(C)NN>>CC(C)(C)N=NC1(NC(=S)NNC(C)(C)C)CCCCC1 -US20050038016A1,1,CNCc1cccc(OCS(C)=O)c1.COc1cc2[nH]c(Cl)nc(=O)c2c(C)c1OC>>COc1cc2[nH]c(N(C)Cc3cccc(OCS(C)=O)c3)nc(=O)c2c(C)c1OC -US05728899,6,CC(=O)O[C@@H]1C=C[C@H](OCc2ccccc2)C1>>O[C@@H]1C=C[C@H](OCc2ccccc2)C1 -US20060270718A1,9,CCC(O)(c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1)c1cccn1CCOC>>CCC(c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1)c1cccn1CCOC -US20120202852A1,4,C#CC(OCC)OCC.C[Si](C)(C)CN=[N+]=[N-]>>CCOC(OCC)c1cn(C[Si](C)(C)C)nn1 -US08569535B2,6,CCOC(=O)C1(NC(=O)c2cc(Cl)cnc2N(C)C(C)C)Cc2ccccc2C1>>CC(C)N(C)c1ncc(Cl)cc1C(=O)NC1(C(=O)O)Cc2ccccc2C1 -US06451821B1,7,CCOC(=O)[C@@H](Cc1ccsc1)NC(C)=O>>CC(=O)N[C@@H](CO)Cc1ccsc1 -US05532243,3,Fc1ccc([Mg+])cc1.O=C1CC[C@@H]2CN(C(=O)c3ccccc3)CC[C@@H]2C1>>O=C(c1ccccc1)N1CC[C@@H]2CC(O)(c3ccc(F)cc3)CC[C@@H]2C1 -US20020193367A1,2,CC(C)(C)OC(=O)CC(=O)c1ccnc(C#N)c1.CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl>>CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2ccnc(C#N)c2)cc1Cl -US06184398B2,6,CCC(O)(CC)CCS[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CCC(O)(CC)CCS[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C -US20150133451A1,6,CCOC(=O)c1coc(-c2ccnc(N(CC(F)(F)F)C(=O)OC(C)(C)C)c2)n1>>CC(C)(C)OC(=O)N(CC(F)(F)F)c1cc(-c2nc(C(=O)O)co2)ccn1 -US20130217666A1,4,ON=C1c2cc(Br)c(F)cc2C2CC1C2>>O=C1NC2CC(C2)c2cc(F)c(Br)cc21 -US07030128B2,3,Brc1ccc(-c2ccccc2)nc1.CCCC[Sn](CCCC)(CCCC)c1cnc2nc(C(F)(F)F)ccn12>>FC(F)(F)c1ccn2c(-c3ccc(-c4ccccc4)nc3)cnc2n1 -US05217971,2,COc1ccc(-c2nc(N)sc2-c2ccc(OC)cc2)cc1.O=C(N=C=S)c1ccccc1>>COc1ccc(-c2nc(NC(=S)NC(=O)c3ccccc3)sc2-c2ccc(OC)cc2)cc1 -US20090124637A1,1,CC(C)C[C@H](CO)Nc1nc(S)nc2nc(N)sc12.C[C@@H](Cl)c1cccc(C#N)c1>>CC(C)C[C@H](CO)Nc1nc(S[C@@H](C)c2cccc(C#N)c2)nc2nc(N)sc12 -US07872018B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(C=O)c(F)cc1OCc1nc2cc(S(=O)(=O)N(C)C)ccc2[nH]1>>COc1cc(C=O)c(F)cc1OCc1nc2cc(S(=O)(=O)N(C)C)ccc2n1C(=O)OC(C)(C)C -US20070232607A1,2,CNCCOC.Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@H](C)C(=O)O)c34)cc2C)cn1>>COCCN(C)C(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c12 -US07223769B2,10,C=C(C)C(C)Oc1cc(OCC#CCC)ncn1.Cl>>CCC#CCOc1cc(OC(C)C(C)(C)Cl)ncn1 -US08415370B2,6,O=C1N(C(c2ccccc2)c2ccccc2)c2cccc(-c3cnc4ccccc4c3)c2C12COc1cc3c(cc12)OCCO3>>O=C1Nc2cccc(-c3cnc4ccccc4c3)c2C12COc1cc3c(cc12)OCCO3 -US20040006141A1,2,NCCCc1ccc(CO)cc1.O=C(O)c1ccc(-c2ccccn2)cc1>>O=C(NCCCc1ccc(CO)cc1)c1ccc(-c2ccccn2)cc1 -US04820834,2,NCC1N=C(c2ccccc2F)c2ccccc2NC1=O.O=C(Cl)c1cc2ccccc2[nH]1>>O=C(NCC1N=C(c2ccccc2F)c2ccccc2NC1=O)c1cc2ccccc2[nH]1 -US20110263658A1,7,COCCCc1ccccc1-c1ccc(C(C#N)Cc2cc(F)cc(F)c2)c(C)c1>>COCCCc1ccccc1-c1ccc(C(CN)Cc2cc(F)cc(F)c2)c(C)c1 -US07507841B2,8,Cc1c2c(c(C(O)c3ccc(C(C)C)cc3)c(C)c1NC(=O)CC(C)(C)C)OC(C)(C)C2>>Cc1c2c(c(C(=O)c3ccc(C(C)C)cc3)c(C)c1NC(=O)CC(C)(C)C)OC(C)(C)C2 -US05663337,1,COCBr.Cc1ccc2ccc3nc(C)[nH]c(=O)c3c2c1>>COCn1c(C)nc2ccc3ccc(C)cc3c2c1=O -US07569578B2,8,Cc1cc(CC(CO)NC(=O)OC(C)(C)C)cc2cn(COCC[Si](C)(C)C)nc12>>Cc1cc(CC(C=O)NC(=O)OC(C)(C)C)cc2cn(COCC[Si](C)(C)C)nc12 -US20070010511A1,7,COC(=O)c1cccc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c12>>OCc1cccc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c12 -US07176215B2,1,OB(O)c1ccccc1.c1cnc2cc[nH]c2c1>>c1ccc(-n2ccc3ncccc32)cc1 -US06083943,6,COC(=O)[C@H]1C[C@H](NCc2cc(OC(F)(F)F)ccc2OC)[C@H](c2ccccc2)N(C(=O)OCc2ccccc2)C1>>COC(=O)[C@@H]1CN[C@@H](c2ccccc2)[C@@H](NCc2cc(OC(F)(F)F)ccc2OC)C1 -US20090270435A1,6,CCOC(=O)c1cc(-c2ccn(C)n2)ccc1Cl>>Cn1ccc(-c2ccc(Cl)c(C(=O)O)c2)n1 -US07812017B2,2,Brc1cccc2[nH]ccc12.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>O=S(=O)(c1cccc(C(F)(F)F)c1)n1ccc2c(Br)cccc21 -US08853226B2,2,COc1cccc2c1ncc1c(=O)n(-c3cccc(Cl)c3)c(=O)n(C3CCNCC3)c12.CS(=O)(=O)Cl>>COc1cccc2c1ncc1c(=O)n(-c3cccc(Cl)c3)c(=O)n(C3CCN(S(C)(=O)=O)CC3)c12 -US04988698,6,CCOC(=O)c1cn2ccc(CC)cc2n1>>CCc1ccn2cc(C(=O)O)nc2c1 -US20140274696A1,6,COC(=O)c1nc(-c2ccc(C#C[Si](C)(C)C)cc2)c(F)c(N)c1Cl>>C#Cc1ccc(-c2nc(C(=O)OC)c(Cl)c(N)c2F)cc1 -US20150197512A1,1,BrCC1CCCO1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCC2CCCO2)cc1 -US20140163001A1,3,CC(C)(C)n1ncc(-c2nc(CC(=O)NCC3CCOCC3)cs2)c1Br.OB(O)c1ccc(Cl)cc1>>CC(C)(C)n1ncc(-c2nc(CC(=O)NCC3CCOCC3)cs2)c1-c1ccc(Cl)cc1 -US20040058903A1,1,CC(C)(C)OC(=O)N(CCc1ccccn1)c1ccc(NC(=O)c2ccccc2-c2ccc(O)cc2)cc1.CCOC(=O)CBr>>CCOC(=O)COc1ccc(-c2ccccc2C(=O)Nc2ccc(N(CCc3ccccn3)C(=O)OC(C)(C)C)cc2)cc1 -US07091216B2,6,CC(=O)OCC(=O)Nc1c(C(=O)C(C)(C)O)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12>>CC(C)(O)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)CO -US20110009454A1,2,NCc1cccc(OCc2ccccc2)c1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1cccc(OCc2ccccc2)c1 -US20090118332A1,2,Cc1ccc(C(=O)O)cc1N.Clc1ccc(C2CCNCC2)cc1>>Cc1ccc(C(=O)N2CCC(c3ccc(Cl)cc3)CC2)cc1N -US07985755B2,2,Nc1nc(N)c2c(N3CCNCC3)cccc2n1.O=S(=O)(Cl)c1ccc(F)cc1>>Nc1nc(N)c2c(N3CCN(S(=O)(=O)c4ccc(F)cc4)CC3)cccc2n1 -US20050267095A1,8,CSc1ccc(C2(C#N)CCOCC2)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc(C2(C#N)CCOCC2)cc1 -US20030069271A1,2,CCO.Nc1ccc(F)cc1C(=O)O>>CCOC(=O)c1cc(F)ccc1N -US05206235,2,CC(C)(CC(=O)O)NC(=O)OC(C)(C)C.NC1CCc2cc(C(F)(F)F)ccc2NC1=O>>CC(C)(CC(=O)NC1CCc2cc(C(F)(F)F)ccc2NC1=O)NC(=O)OC(C)(C)C -US20110262352A1,4,ClCCN(CCCl)C[C@H]1COc2ccccc2O1.Nc1cccc(CO)c1>>OCc1cccc(N2CCN(C[C@H]3COc4ccccc4O3)CC2)c1 -US20110034434A1,1,CCC(Cl)OC(C)=O.O=C(O)c1cc2occc2[nH]1>>CCC(OC(C)=O)OC(=O)c1cc2occc2[nH]1 -US07935721B2,1,BrCc1ccc2nonc2c1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCO3>>O=C1N(Cc2ccc3nonc3c2)c2ccccc2C12COc1cc3c(cc12)OCO3 -US20020115640A1,3,COc1ccc(Cl)cc1I.OB(O)c1cccc(Cl)c1>>COc1ccc(Cl)cc1-c1cccc(Cl)c1 -US20080261941A1,6,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(OCc3ccccc3)c2)CC1>>C(=C1CCNCC1)c1cccc(OCc2ccccc2)c1 -US07727988B2,1,COC(CCBr)OC.Cc1ccncc1-c1c[nH]c(=O)[nH]c1=O>>COC(CCn1cc(-c2cnccc2C)c(=O)[nH]c1=O)OC -US04465690,2,CC(C)O.O=C(Cl)C(Cl)=C(Cl)Cl>>CC(C)OC(=O)C(Cl)=C(Cl)Cl -US05874436,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1cccc(O)c1>>CC(C)(C)OC(=O)NCCc1cccc(O)c1 -US20150166480A1,1,CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)CC1.N#Cc1cc(O)ccc1Br>>CC(C)(C)OC(=O)N1CCC(COc2ccc(Br)c(C#N)c2)CC1 -US05204358,1,CN(C)C(=O)CCS.COC(=O)c1cncc(C(Cl)c2cccc(OCc3ccc4ccc(Cl)cc4n3)c2)c1>>COC(=O)c1cncc(C(SCCC(=O)N(C)C)c2cccc(OCc3ccc4ccc(Cl)cc4n3)c2)c1 -US08198279B2,1,CCOC(=O)c1cc(C(C)(C)C)n[nH]1.CN(C)CCCl>>CCOC(=O)c1cc(C(C)(C)C)nn1CCN(C)C -US06784167B2,3,CN1C(=O)C[C@H](c2ccccc2)[C@@H]1[C@H](O)c1ccc(Br)s1.OB(O)c1ccc(F)c(Cl)c1>>CN1C(=O)C[C@H](c2ccccc2)[C@@H]1[C@H](O)c1ccc(-c2ccc(F)c(Cl)c2)s1 -US20050032873A1,1,Fc1ccc2[nH]cc(CCCBr)c2c1.NC(=O)c1ccc(F)c2c1CC(N)CO2>>NC(=O)c1ccc(F)c2c1CC(NCCCc1c[nH]c3ccc(F)cc13)CO2 -US20110237578A1,2,C[C@@H](N)CN1CCOCC1.Cc1ccc(-c2cc(C(=O)O)cc(-c3cccc(F)c3F)c2)nc1>>Cc1ccc(-c2cc(C(=O)N[C@H](C)CN3CCOCC3)cc(-c3cccc(F)c3F)c2)nc1 -US20040110767A1,1,C1=COCCC1.O=Cc1cccc(O)c1>>O=Cc1cccc(OC2CCCCO2)c1 -US20140274688A1,3,COC(=O)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.FC(F)(F)C(F)(F)Oc1ccc(-n2cnc(Br)n2)cc1>>COC(=O)Cc1ccc(-c2ncn(-c3ccc(OC(F)(F)C(F)(F)F)cc3)n2)cc1 -US04522991,2,CC(C)(O)C#N.O=C(Cl)Cl>>CC(C)(C#N)OC(=O)Cl -US20100256156A1,7,COC(=O)c1cc(Br)oc1C>>Cc1oc(Br)cc1CO -US20080318943A1,3,COc1ccc(F)c(B(O)O)c1F.Nc1c2c(nc3c(Br)c(F)ccc13)CN(C1CC1)C2=O>>COc1ccc(F)c(-c2c(F)ccc3c(N)c4c(nc23)CN(C2CC2)C4=O)c1F -US20120040999A1,7,COC(=O)c1cc(C(=O)c2c(F)cc(F)cc2F)c[nH]1>>COC(=O)c1cc(Cc2c(F)cc(F)cc2F)c[nH]1 -US20100144694A1,1,CC1(C)NN(C2C3CC4CC(C3)CC2C4)C1=O.Fc1cccc(Cl)c1CBr>>CC1(C)C(=O)N(C2C3CC4CC(C3)CC2C4)N1Cc1c(F)cccc1Cl -US05037834,1,CCOC(=O)C(=CNc1ccc(F)cc1)C(=O)c1cc(F)c(F)cc1Cl>>CCOC(=O)c1cn(-c2ccc(F)cc2)c2cc(F)c(F)cc2c1=O -US04599336,1,ClCc1ccncc1.NCCS>>NCCSCc1ccncc1 -US08063099B2,2,NC[C@@H]1[C@H]2C[C@H]2CN1C(=O)c1nc(N)sc1-c1cccc(F)c1.O=C(O)c1cnn2ccccc12>>Nc1nc(C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2cnn3ccccc23)c(-c2cccc(F)c2)s1 -US08063222B2,6,CCOC(=O)N1CCC(NS(=O)(=O)c2cccc3c(CN4C(=O)c5ccccc5C4=O)cccc23)CC1>>CCOC(=O)N1CCC(NS(=O)(=O)c2cccc3c(CN)cccc23)CC1 -US07951806B2,2,CC(C)(C)OC(=O)c1c(-c2ccccc2)csc1NC(=O)CCCCC(=O)O.COC(=O)c1cc(Cl)ccc1N>>COC(=O)c1cc(Cl)ccc1NC(=O)CCCCC(=O)Nc1scc(-c2ccccc2)c1C(=O)OC(C)(C)C -US07265150B1,9,CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)O.N>>CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(N)=O -US08614220B2,7,Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc([N+](=O)[O-])ccc3OC(F)(F)F)ncc1CC2>>Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N)ccc3OC(F)(F)F)ncc1CC2 -US20050261331A1,9,N#Cc1ccc(Cl)nc1.NN>>N#Cc1ccc(NN)nc1 -US20050009843A1,2,CC(C)(C)OC(=O)NCCC(=O)O.COc1ccc(Cn2nnnc2/C=C/c2c(N3CCNCC3)nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c2=O)cc1>>COc1ccc(Cn2nnnc2/C=C/c2c(N3CCN(C(=O)CCNC(=O)OC(C)(C)C)CC3)nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c2=O)cc1 -US20100099681A1,3,CC1(C)OB(c2cc(F)c3nccnc3c2)OC1(C)C.COC(=O)c1ccccc1Nc1c(Br)c(C)nn1-c1cc(F)ccc1F>>COC(=O)c1ccccc1Nc1c(-c2cc(F)c3nccnc3c2)c(C)nn1-c1cc(F)ccc1F -US20090105124A1,2,COC(=O)c1nccnc1NC(=O)c1ccc(F)cc1.NN>>NNC(=O)c1nccnc1NC(=O)c1ccc(F)cc1 -US20140329797A1,1,CC(C)(c1ccc(-c2noc(-c3ccc(=O)[nH]n3)n2)cc1)C(F)(F)F.CS(=O)(=O)OCc1ccnc(Cl)c1>>CC(C)(c1ccc(-c2noc(-c3ccc(=O)n(Cc4ccnc(Cl)c4)n3)n2)cc1)C(F)(F)F -US20070225349A1,2,CNOC.O=C(O)c1cccc(F)c1F>>CON(C)C(=O)c1cccc(F)c1F -US06258824B1,1,BrCC1CC1.Cn1cncc1C(O)(c1ccc(Cl)nc1)c1ccc2[nH]c(=O)cc(-c3cccc(Cl)c3)c2c1>>Cn1cncc1C(O)(c1ccc(Cl)nc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2CC1CC1 -US20090036450A1,4,CC(N)=S.CCOC(=O)C(Cl)C(=O)C12CC3CC(CC(C3)C1)C2>>CCOC(=O)c1sc(C)nc1C12CC3CC(CC(C3)C1)C2 -US20150011528A1,6,CCOC(=O)c1ccc2nc(NC(=O)c3ccc(C)cc3)sc2c1>>Cc1ccc(C(=O)Nc2nc3ccc(C(=O)O)cc3s2)cc1 -US05837708,1,CC(C)c1ccc(S(N)(=O)=O)nc1.COc1cccc(Cc2nc(Cl)c(Oc3ccccc3)c(Cl)n2)c1>>COc1cccc(Cc2nc(Cl)c(Oc3ccccc3)c(NS(=O)(=O)c3ccc(C(C)C)cn3)n2)c1 -US20100190747A1,2,C#CCCN.O=C(Cl)CCl>>C#CCCNC(=O)CCl -US20110117073A1,1,CC(C)(C)OC(=O)NCCSc1nc(Cl)cc(Nc2ncc(C#N)s2)n1.CN1CCNCC1>>CN1CCN(c2cc(Nc3ncc(C#N)s3)nc(SCCNC(=O)OC(C)(C)C)n2)CC1 -US08058045B2,6,CCOC(=O)c1ccn(-c2cnc(Nc3cnc(C#N)cn3)cc2NCC2CCCN(C(=O)OC(C)(C)C)C2)c1>>CC(C)(C)OC(=O)N1CCCC(CNc2cc(Nc3cnc(C#N)cn3)ncc2-n2ccc(C(=O)O)c2)C1 -US20060173050A1,1,CCO.N#Cc1c(N)cc(N)nc1Br>>CCOc1nc(N)cc(N)c1C#N -US20070269664A1,7,O=C(O)Cc1cc(F)cc(F)c1>>OCCc1cc(F)cc(F)c1 -US04855324,1,C#CC(O)CCCCCCCC.CCCC[SnH](CCCC)CCCC>>CCCCCCCCC(O)/C=C/[Sn](CCCC)(CCCC)CCCC -US05008267,1,BrCCCBr.O=[N+]([O-])c1ccc(S)cc1>>O=[N+]([O-])c1ccc(SCCCBr)cc1 -US20130210827A1,2,C1C[C@@H]2CNCCN2C1.CC(C)N(c1cccc(C(=O)O)c1)S(=O)(=O)c1cccc(C(F)(F)F)c1>>CC(C)N(c1cccc(C(=O)N2CCN3CCC[C@@H]3C2)c1)S(=O)(=O)c1cccc(C(F)(F)F)c1 -US08871798B2,3,CN1C(=O)C2C(C1=O)C1CCCCN1C2/C=C/c1ccc(Br)cn1.COc1ccccc1B(O)O>>COc1ccccc1-c1ccc(/C=C/C2C3C(=O)N(C)C(=O)C3C3CCCCN23)nc1 -US20140024650A1,1,CC(C)(C)OC(=O)N[C@H]1CCOC[C@@H]1CO.Oc1ccc(-c2ccc(F)cn2)c(F)c1F>>CC(C)(C)OC(=O)N[C@H]1CCOC[C@@H]1COc1ccc(-c2ccc(F)cn2)c(F)c1F -US20120165310A1,6,CC1(C)CCC(COc2cccc(-c3cn(C4CCC5(CC4)OCCO5)c4ncnc(N)c34)c2)O1>>CC1(C)CCC(COc2cccc(-c3cn(C4CCC(=O)CC4)c4ncnc(N)c34)c2)O1 -US08314100B2,2,CCOC(=O)Nc1nc2cc(C)ccc2nc1OC.Fc1ccc(N2CCNCC2)cc1>>COc1nc2ccc(C)cc2nc1NC(=O)N1CCN(c2ccc(F)cc2)CC1 -US20090306133A1,2,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3cccc(CN)c3)nc3ccccc23)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3cccc(CNS(C)(=O)=O)c3)nc3ccccc23)CC1 -US04783472,7,O=[N+]([O-])c1cccc(Oc2cccnc2)c1>>Nc1cccc(Oc2cccnc2)c1 -US04153717,2,CN(Cc1ccco1)[C@@H]1CCCC[C@H]1N.O=C(Cl)c1ccc(Cl)c(Cl)c1>>CN(Cc1ccco1)[C@@H]1CCCC[C@H]1NC(=O)c1ccc(Cl)c(Cl)c1 -US07732473B2,1,Ic1ccccc1.O=C1CN2C(=O)CCC2N1>>O=C1CCC2N1CC(=O)N2c1ccccc1 -US20100075959A1,6,COc1ccc(N2CCN(C(=O)OCc3ccccc3)CC2)c2sc(NC(=O)c3ccc(C)s3)nc12>>COc1ccc(N2CCNCC2)c2sc(NC(=O)c3ccc(C)s3)nc12 -US07064124B2,2,COC1=C(OC)C(=O)C(Cc2ccc(C(=O)O)c(OC(C)=O)c2)=C(C)C1=O.Nc1ccc(S(=O)(=O)C(F)(F)F)cc1>>COC1=C(OC)C(=O)C(Cc2ccc(C(=O)Nc3ccc(S(=O)(=O)C(F)(F)F)cc3)c(OC(C)=O)c2)=C(C)C1=O -US20140371199A1,3,N#Cc1ccc(-c2cnc3cnc(Br)cn23)cc1.O=C(O)c1ccc(B(O)O)c(F)c1>>N#Cc1ccc(-c2cnc3cnc(-c4ccc(C(=O)O)cc4F)cn23)cc1 -US20100016300A1,1,Nc1ccc2[nH]ncc2c1.O=C(O)c1c(F)ccc([N+](=O)[O-])c1F>>O=C(O)c1c(F)ccc([N+](=O)[O-])c1Nc1ccc2[nH]ncc2c1 -US20140155384A1,3,Cc1ccc(B2OC(C)(C)C(C)(C)O2)cn1.Cc1ccc2c(c1)c1c(n2-c2ccccc2Br)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2-c2ccccc2-c2ccc(C)nc2)CCN(C)C1 -US20090005415A1,2,Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1.O=S(=O)(Cl)CCCC(F)(F)F>>Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCCC(F)(F)F)cc1 -US20080312234A1,2,C#Cc1cc(CN)cc(F)c1NS(C)(=O)=O.Cc1nc(C(F)(F)F)ccc1C=CC(=O)O>>C#Cc1cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2C)cc(F)c1NS(C)(=O)=O -US08188114B2,1,CCC(=O)CC.NNc1cccnc1Cl>>CCC(CC)=NNc1cccnc1Cl -US05646308,7,CNC(=S)C1=C(O)C2(CCOCC2)Oc2ccc([N+](=O)[O-])cc21>>CNC(=S)C1c2cc([N+](=O)[O-])ccc2OC2(CCOCC2)C1O -US20090324581A1,8,OCc1ccc(C(F)(F)F)cc1C(F)(F)F>>O=Cc1ccc(C(F)(F)F)cc1C(F)(F)F -US20120270875A1,6,COC(=O)[C@H](CNC(=O)c1cccc(C)c1)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C>>Cc1cccc(C(=O)NC[C@H](NC(=O)c2c(C)nc(NCCCc3cccc(O)c3)nc2C)C(=O)O)c1 -US08173821B2,7,CC(C)(C)OC(=O)N1CC[C@H](C(=O)C2CCC2)C1>>CC(C)(C)OC(=O)N1CC[C@H](C(O)C2CCC2)C1 -US05032165,9,CSc1c(Cl)c(-c2cc(S(=O)(=O)Cl)c(Cl)cc2Cl)nn1C>>CSc1c(Cl)c(-c2cc(S)c(Cl)cc2Cl)nn1C -US20140127709A1,3,CC(C)=CCCC(C)CCBr.[Mg+]CCCCCCOC1CCCCO1>>CC(C)=CCC[C@H](C)CCCCCCCCOC1CCCCO1 -US20080139558A1,2,O=C(O)c1ccncc1.O=c1cc(CNc2ccccc2)c2ccccc2[nH]1>>O=C(c1ccncc1)N(Cc1cc(=O)[nH]c2ccccc12)c1ccccc1 -US20060079548A1,1,CCn1c(C)c(C(=O)NC)c2ccc(O)cc21.O=C(c1cc2nccc(Cl)c2s1)N1CCC1>>CCn1c(C)c(C(=O)NC)c2ccc(Oc3ccnc4cc(C(=O)N5CCC5)sc34)cc21 -US20120202763A1,6,CC(C)(C)OC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1>>N#Cc1ccc(OC2CCNCC2)cc1 -US20070249620A1,7,Cc1ccc(OCCO[Si](C)(C)C(C)(C)C)cc1[N+](=O)[O-]>>Cc1ccc(OCCO[Si](C)(C)C(C)(C)C)cc1N -US05877202,2,CC(C)(C)OC(=O)NCCCCCCCC(=O)O.CCCCNC>>CCCCN(C)C(=O)CCCCCCCNC(=O)OC(C)(C)C -US05026856,6,CCOC(=O)c1cn(C2CC2)c2nc(N3Cc4ccccc4C3)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2nc(N3Cc4ccccc4C3)c(F)cc2c1=O -US20080194535A1,1,C=CCBr.COc1ccc2c(c1)C(N=[N+]=[N-])C(O)C2>>C=CCO[C@@H]1Cc2ccc(OC)cc2[C@H]1N=[N+]=[N-] -US20060173018A1,1,CC(C)(C)OC(=O)NC1CCNCC1.Oc1ccccc1-c1nc(Cl)c2ccccc2n1>>CC(C)(C)OC(=O)NC1CCN(c2nc(-c3ccccc3O)nc3ccccc23)CC1 -US08586566B2,3,C=Cn1cnc2c(Nc3ccc(P(C)(C)=O)cc3)ncnc21.Cc1ccnc(Cl)c1I>>Cc1ccnc(Cl)c1/C=C/n1cnc2c(Nc3ccc(P(C)(C)=O)cc3)ncnc21 -US20060069126A1,6,CC(=O)OC1CC(N2Cc3c(cccc3[N+](=O)[O-])C2=O)C(=O)NC1=O>>O=C1NC(=O)C(N2Cc3c(cccc3[N+](=O)[O-])C2=O)CC1O -US20080064720A1,7,COC(=O)[C@@H](Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)NC(=O)c1c(Cl)cccc1Cl>>O=C(N[C@@H](CO)Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)c1c(Cl)cccc1Cl -US07674802B2,9,N.O=C(O)C1CCN(CCCOc2ccc(-n3nc4ccccc4c3Cl)cc2)CC1>>NC(=O)C1CCN(CCCOc2ccc(-n3nc4ccccc4c3Cl)cc2)CC1 -US20100144731A1,1,COC(=O)C1(c2ccc(N)cc2)CCCC1.Clc1nc(C2CCCC2)nc2c1CCC2>>COC(=O)C1(c2ccc(Nc3nc(C4CCCC4)nc4c3CCC4)cc2)CCCC1 -US20140038919A1,7,COC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(Cc3ccc(OC)cc3)S(C)(=O)=O)c(OC(C)C)cc12>>COc1ccc(CN(c2cc3oc(-c4ccc(F)cc4)c(CO)c3cc2OC(C)C)S(C)(=O)=O)cc1 -US20150197539A1,3,CCN(CC)C(=O)c1cccc(OCOC)c1.CN(C)C=O>>CCN(CC)C(=O)c1cccc(OCOC)c1C=O -US04788206,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COc1ccc(/C(=C\C=O)c2cccnc2)cc1>>COC(=O)/C=C/C=C(\c1ccc(OC)cc1)c1cccnc1 -US20130296327A1,2,CN1CCN(c2cc(-c3ccc4c(c3)CNCC4)nc(N)n2)CC1.O=C(O)CC1CCOCC1>>CN1CCN(c2cc(-c3ccc4c(c3)CN(C(=O)CC3CCOCC3)CC4)nc(N)n2)CC1 -US20130281467A1,3,Brc1cccc(-c2ncc3c(n2)CCOC3)n1.Cc1ccccc1C[Zn+]>>Cc1ccccc1Cc1cccc(-c2ncc3c(n2)CCOC3)n1 -US20090197875A1,8,COc1cc(N2CCSCC2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1.O=S([O-])OO>>COc1cc(N2CCS(=O)CC2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1 -US20100121091A1,1,C1=COCCC1.O=C(NCCO)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Br>>O=C(NCCOC1CCCCO1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Br -US07960404B2,6,COc1ccc(CNC2(Cc3ccccc3)CCC3(CC2)OCCO3)cc1>>COc1ccc(CNC2(Cc3ccccc3)CCC(=O)CC2)cc1 -US06861418B2,3,Cc1cc(C(=O)NCCN2CCCC2)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2ccc(F)c(Cl)c2)N1>>Cc1cc(C(=O)NCCN2CCCC2)c(C=C2C(=O)Nc3cccc(-c4ccc(F)c(Cl)c4)c32)[nH]1 -US20090197959A1,3,CCN(Cc1cc(Br)ccc1I)C(=O)OC(C)(C)C.CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(Br)cc2CN(CC)C(=O)OC(C)(C)C)c1 -US08410302B2,3,ClC(Cl)(Cl)Cl.O=Cc1ccc(O)c(Cl)c1>>Oc1ccc(C(O)C(Cl)(Cl)Cl)cc1Cl -US20140378487A1,1,COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.NCc1ccc(Oc2cccc(C(F)(F)F)c2)c(F)c1>>COc1ccc2c(c1)CCn1c-2cc(NCc2ccc(Oc3cccc(C(F)(F)F)c3)c(F)c2)nc1=O -US07705023B2,1,Brc1ccc(OC2CC2)cc1.CCOC(=O)c1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2[nH]1>>CCOC(=O)c1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC2CC2)cc1 -US20150191452A1,6,Cc1ccc(CN2CC[C@@H](N3CC[C@H](c4ccc(OCc5ccccc5)cc4)C(F)C3)C2=O)cc1>>Cc1ccc(CN2CCC(N3CC[C@H](c4ccc(O)cc4)[C@@H](F)C3)C2=O)cc1 -US20140200225A1,1,CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cc(O)cc(Oc3ccc(C#N)cc3)c2)CC1.O=[N+]([O-])c1ccc(Cl)cn1>>CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cc(Oc3ccc(C#N)cc3)cc(Oc3ccc([N+](=O)[O-])nc3)c2)CC1 -US20110076291A1,1,CC(C)NC(=O)CCl.Cc1nc(-c2nc3c(s2)CCOc2cc(C4CNC4)ccc2-3)n(C(C)C)n1>>Cc1nc(-c2nc3c(s2)CCOc2cc(C4CN(CC(=O)NC(C)C)C4)ccc2-3)n(C(C)C)n1 -US20050009843A1,6,CN(C)CCNC(=O)O[C@@H]1CCCN(c2nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c(=O)c2/C=C/C(=O)OC(C)(C)C)C1>>CN(C)CCNC(=O)O[C@@H]1CCCN(c2nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c(=O)c2/C=C/C(=O)O)C1 -US20070149502A1,6,CCOC(=O)C1(Cc2ccccc2N)CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(Cc2ccccc2N)CCNCC1 -US08258134B2,2,CC(C)CC(C(=O)O)n1ncc(I)cc1=O.CC1(C)OC[C@@H](Cn2ccc(N)n2)O1>>CC(C)CC(C(=O)Nc1ccn(C[C@@H]2COC(C)(C)O2)n1)n1ncc(I)cc1=O -US07649093B2,6,CCOC(=O)/C=C/c1ccc(Oc2c(-c3ccccc3)c(C(C)C)cc3cc(OC)ccc23)cc1>>COc1ccc2c(Oc3ccc(/C=C/C(=O)O)cc3)c(-c3ccccc3)c(C(C)C)cc2c1 -US09045433B2,4,C=CCc1cccc(C)c1C.OO>>Cc1cccc(CC2CO2)c1C -US20100029657A1,1,C[O-].N#Cc1ccc(Br)cc1F>>COc1cc(Br)ccc1C#N -US08129403B2,1,Nc1cc(C2CC2)[nH]n1.O=[N+]([O-])c1cc(F)c(F)c(F)c1F>>O=[N+]([O-])c1cc(F)c(F)c(F)c1Nc1cc(C2CC2)[nH]n1 -US20150152113A1,2,NNc1cc(N2CCC(c3ccccc3F)CC2)ncn1.O=C(Cl)CC(F)(F)F>>O=C(CC(F)(F)F)NNc1cc(N2CCC(c3ccccc3F)CC2)ncn1 -US20080027049A1,2,Nc1ccc2oc3c(c2c1)CCCCCC3.O=C(Cl)CCl>>O=C(CCl)Nc1ccc2oc3c(c2c1)CCCCCC3 -US06878712B1,1,C[C@H]1CN(S(=O)(=O)c2ccc(F)cc2)[C@H](C)CN1C(=O)[C@@](C)(O)C(F)(F)F.NCCO>>C[C@H]1CN(S(=O)(=O)c2ccc(NCCO)cc2)[C@H](C)CN1C(=O)[C@@](C)(O)C(F)(F)F -US20080318943A1,3,Nc1c2c(nc3c(Br)c(F)ccc13)CN(C1CCC1)C2=O.OB(O)c1cccnc1F>>Nc1c2c(nc3c(-c4cccnc4F)c(F)ccc13)CN(C1CCC1)C2=O -US20080039459A1,2,CN.O=C(O)c1cc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2s1>>CNC(=O)c1cc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2s1 -US20080207634A1,8,CN1CCN(c2cccc3nc(CO)cn23)CC1>>CN1CCN(c2cccc3nc(C=O)cn23)CC1 -US08324186B2,1,O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CNC1.O=C1CCC(n2cc(I)ccc2=O)CC1>>O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(n3cc(I)ccc3=O)CC2)C1 -US20080242685A1,6,CC(C)(C)OC(=O)N1CCC(c2c[nH]c3c(C(N)=O)nc(-c4ccccc4)cc23)CC1>>NC(=O)c1nc(-c2ccccc2)cc2c(C3CCNCC3)c[nH]c12 -US20100105655A1,7,CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(C#N)c2)CC1>>CC(=O)N1CCN(c2ccc(N)c(C#N)c2)CC1 -US03975389,1,CC(Cl)c1nc2c(c(=O)n(C)c(=O)n2C)n1C.O=C([O-])c1cccnc1>>CC(OC(=O)c1cccnc1)c1nc2c(c(=O)n(C)c(=O)n2C)n1C -US07282586B1,4,N#Cc1ccc2ccc3cccnc3c2n1.[N-]=[N+]=[N-]>>c1cnc2c(c1)ccc1ccc(-c3nnn[nH]3)nc12 -US20030027823A1,1,ClC/C=C\CCl.O=c1[nH]c2ccccc2n1CCOC1CCCCO1>>O=c1n(C/C=C\CCl)c2ccccc2n1CCOC1CCCCO1 -US20100076014A1,2,CC(C)/C=C(\c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)C(=O)O.Nc1nncs1>>CC(C)/C=C(\c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)C(=O)Nc1nncs1 -US20040106645A1,1,NC1CCN(Cc2ccc3ccccc3c2)CC1.O=c1cc(OS(=O)(=O)C(F)(F)F)c2cc(OC(F)F)ccc2o1>>O=c1cc(NC2CCN(Cc3ccc4ccccc4c3)CC2)c2cc(OC(F)F)ccc2o1 -US20140107073A1,7,C1=C(c2cccc(-c3ncccc3-c3cnc4[nH]ncc4c3)c2)CCC1>>c1cc(-c2ncccc2-c2cnc3[nH]ncc3c2)cc(C2CCCC2)c1 -US04460777,2,CN.COC(=O)CCCCCCCn1c(-c2cccnc2)c(C)c2ccccc21>>CNC(=O)CCCCCCCn1c(-c2cccnc2)c(C)c2ccccc21 -US20060258666A1,3,CC1(C)CC=C(B(O)O)CC1.N#Cc1ccc(N)c(Br)c1>>CC1(C)CC=C(c2cc(C#N)ccc2N)CC1 -US08501794B2,2,CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)[C@]1(C)CC[C@H](C(=O)O)C1(C)C.NC1CC1>>CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)[C@]1(C)CC[C@H](C(=O)NC2CC2)C1(C)C -US07105558B2,6,COC(=O)c1cccc(NC(=O)c2nn(-c3c(Cl)cccc3Cl)nc2COc2ccccc2)c1>>O=C(O)c1cccc(NC(=O)c2nn(-c3c(Cl)cccc3Cl)nc2COc2ccccc2)c1 -US07238714B2,1,COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)cnc2Cl)cc1.Oc1cccc(-c2ccncc2)c1>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)cnc2Oc2cccc(-c3ccncc3)c2)cc1 -US20100286161A1,6,Cc1cc(C)n(-c2cnc(C3OCCO3)c(Nc3ccc(Cl)cc3)n2)n1>>Cc1cc(C)n(-c2cnc(C=O)c(Nc3ccc(Cl)cc3)n2)n1 -US07115750B1,2,Nc1ccc2ccccc2n1.O=C([O-])c1ccc(COc2ccc3c(c2)CCC(CCN2CCCCC2)C3)cc1>>O=C(Nc1ccc2ccccc2n1)c1ccc(COc2ccc3c(c2)CCC(CCN2CCCCC2)C3)cc1 -US20030092762A1,6,CCCCCCCCCCCCCCCCCC(CCC(=O)OC)[N+](=O)[O-]>>CCCCCCCCCCCCCCCCCC(CCC(=O)O)[N+](=O)[O-] -US05723450,1,C[O-].Clc1nccc(N[C@H]2CC[C@@H](c3ccccc3)CC2)c1Br>>COc1nccc(N[C@H]2CC[C@@H](c3ccccc3)CC2)c1Br -US20150011774A1,1,CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2C(N)=NO)cc1.Cc1oc(=O)oc1CCl>>CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2C(N)=NO)cc1 -US03939166,1,CCCCCC#CCN.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c2[nH]c(C(F)(F)F)nc12>>CCCCCC#CCNc1c(C(F)(F)F)cc([N+](=O)[O-])c2nc(C(F)(F)F)[nH]c12 -US08178549B2,2,Cc1nc(-c2c[nH]c(=O)[nH]c2=O)sc1C.O=C(Cl)c1ccccc1>>Cc1nc(-c2c[nH]c(=O)n(C(=O)c3ccccc3)c2=O)sc1C -US20100099679A1,6,Nc1nccn2c(C3CCN(C(=O)OCc4ccccc4)CC3)nc(-c3cc4ccccc4[nH]3)c12>>Nc1nccn2c(C3CCNCC3)nc(-c3cc4ccccc4[nH]3)c12 -US20080227839A1,1,CC(C)Cn1c(N)nc2ccc(C=O)cc21.CN>>CN=Cc1ccc2nc(N)n(CC(C)C)c2c1 -US20120046278A1,2,Cc1cccc(N=C=O)c1.Nc1nc(N2CCNCC2)c2nc(-c3cccnc3)sc2n1>>Cc1cccc(NC(=O)N2CCN(c3nc(N)nc4sc(-c5cccnc5)nc34)CC2)c1 -US07893099B2,9,COC(=O)[C@H]1C[C@H](S(=O)(=O)c2ccc(Br)cc2C(F)(F)F)C[C@@H]1OC.[N-]=[N+]=[N-]>>COC(=O)[C@H]1C[C@H](S(=O)(=O)c2ccc(N=[N+]=[N-])cc2C(F)(F)F)C[C@@H]1OC -US07709471B2,1,CNC(=O)CCN(CC1CC1)c1nc(Cl)ncc1Br>>CN1C(=O)CCN(CC2CC2)c2nc(Cl)ncc21 -US20140179662A1,1,NC(=O)[C@H]1CCCN1.NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1>>NC(=O)[C@H]1CCCN1c1ncnc(Nc2cccc(CS(N)(=O)=O)c2)n1 -US20040063761A1,9,COC(=O)c1ccccc1-c1ccc(CN=[N+]=[N-])nc1>>COC(=O)c1ccccc1-c1ccc(CN)nc1 -US05703098,1,CCOc1cc(C(CCO)N2C(=O)c3ccccc3C2=O)ccc1OC.CI>>CCOc1cc(C(CCOC)N2C(=O)c3ccccc3C2=O)ccc1OC -US08980913B2,6,CC(C)(C)[Si](C)(C)OCCN(CCC1OCCO1)Cc1ccccc1>>CC(C)(C)[Si](C)(C)OCCNCCC1OCCO1 -US20140005213A1,4,CC(C)(C)OC(=O)NC1(CF)CCN([C@H](c2ccc(NN)nc2)C(F)(F)F)C1.COc1cccc2ccc(C=O)nc12>>COc1cccc2ccc(-c3nnc4ccc([C@@H](N5CCC(CF)(NC(=O)OC(C)(C)C)C5)C(F)(F)F)cn34)nc12 -US20100168418A1,6,COc1ccc2c(/C=C/C(N)=O)cc(=O)n(CC3OCCO3)c2c1>>COc1ccc2c(/C=C/C(N)=O)cc(=O)n(CC=O)c2c1 -US06265349B1,6,COCc1cc2c(-c3ccc(C(F)(F)F)n(C)c3=O)c(F)cc(Cl)c2o1>>Cn1c(C(F)(F)F)ccc(-c2c(F)cc(Cl)c3oc(CO)cc23)c1=O -US08183246B2,1,CNCC(C)Oc1ncnc2oc(-c3ccccc3)c(-c3ccc(OC)cc3)c12.COC(=O)CCCBr>>COC(=O)CCCN(C)CC(C)Oc1ncnc2oc(-c3ccccc3)c(-c3ccc(OC)cc3)c12 -US20140213448A1,1,BrCC1CO1.O=C(CCSCCC(F)(F)F)Nc1cn(-c2cccnc2)nc1Cl>>O=C(CCSCCC(F)(F)F)N(CC1CO1)c1cn(-c2cccnc2)nc1Cl -US20090018131A1,3,Brc1ccc2ncnc(I)c2c1.N#Cc1cccc(B(O)O)c1>>N#Cc1cccc(-c2ncnc3ccc(Br)cc23)c1 -US08063099B2,2,Cc1nc2sccn2c1C(=O)NC[C@H]1NC[C@@H]2C[C@@H]21.O=C(O)c1ccccc1C1CCCCC1>>Cc1nc2sccn2c1C(=O)NC[C@@H]1[C@H]2C[C@H]2CN1C(=O)c1ccccc1C1CCCCC1 -US04649160,1,CSc1ccc(CCO)cc1.O=C(O)CCl>>CSc1ccc(CCOCC(=O)O)cc1 -US20080076806A1,2,NC(c1ccccc1)c1cccs1.O=C(O)CNC(=O)c1ccc(F)cc1>>O=C(CNC(=O)c1ccc(F)cc1)NC(c1ccccc1)c1cccs1 -US07122535B2,6,COC(=O)CCc1cc(C(C)C)c(O)c(C(C)C)c1>>CC(C)c1cc(CCC(=O)O)cc(C(C)C)c1O -US06355798B1,1,CN(C)CCN.Clc1nn2c(-c3ccccc3)nnc2cc1C1CCC1>>CN(C)CCNc1nn2c(-c3ccccc3)nnc2cc1C1CCC1 -US05968923,2,C1CSCCN1.O=C(Cl)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCSCC1 -US07488832B2,6,CCOC(=O)c1ccc(C(=O)CCC(=O)c2ccccc2)cc1>>O=C(O)c1ccc(C(=O)CCC(=O)c2ccccc2)cc1 -US08575208B2,2,CC(C)(C)[C@H](NC(=O)CC1CCCCC1)C(=O)N1C[C@@]2(C[C@H]1C(=O)O)CN(c1ccccc1)C(=O)O2.CCC[C@H](N)C(O)C(=O)NC1CC1>>CCC[C@H](NC(=O)[C@@H]1C[C@@]2(CN(c3ccccc3)C(=O)O2)CN1C(=O)[C@@H](NC(=O)CC1CCCCC1)C(C)(C)C)C(O)C(=O)NC1CC1 -US20140057902A1,2,CC(C)(C)OC(=O)NCC(=O)O.COC(=O)CC1NCCc2c1ccc(F)c2Br>>COC(=O)CC1c2ccc(F)c(Br)c2CCN1C(=O)CNC(=O)OC(C)(C)C -US08957068B2,2,COC(=O)[C@H](C)NC(=O)OC(C)(C)C.NN>>C[C@H](NC(=O)OC(C)(C)C)C(=O)NN -US08877780B2,2,NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O.O=C(Cl)N1CCOCC1>>O=C1CCC(N2Cc3cc(CNC(=O)N4CCOCC4)ccc3C2=O)C(=O)N1 -US20070244153A1,2,CC(C)(C)OC(=O)NC(C)(C)C(=O)O.CC(C)[C@H](N)CNC(=O)c1cc2ccccc2o1>>CC(C)[C@@H](CNC(=O)c1cc2ccccc2o1)NC(=O)C(C)(C)NC(=O)OC(C)(C)C -US20090105252A1,7,Cc1ncc(-c2nc(Nc3ccc(C(=O)c4ccccn4)cc3)ncc2F)n1C>>Cc1ncc(-c2nc(Nc3ccc(C(O)c4ccccn4)cc3)ncc2F)n1C -US20110046134A1,2,NCC(=O)N1CCN(C(=O)c2cc(Cl)ccc2Cl)CC1.O=C(O)c1cc(-c2ccccc2)on1>>O=C(NCC(=O)N1CCN(C(=O)c2cc(Cl)ccc2Cl)CC1)c1cc(-c2ccccc2)on1 -US20150166868A1,1,CCCCCCCCCCCCN(C)C.OCC(O)CCl>>CCCCCCCCCCCC[N+](C)(C)CC(O)CO -US20060234997A1,3,CC(C)(C)C(=O)Nc1nc(OCCCCOCc2ccccc2)ccc1C=O.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>COC=Cc1ccc(OCCCCOCc2ccccc2)nc1NC(=O)C(C)(C)C -US20040110773A1,1,CC(Br)c1cnc(Cl)nc1Cl.COc1ccc(N)cc1>>COc1ccc(NC(C)c2cnc(Cl)nc2Cl)cc1 -US07902356B2,1,BrCc1ccccn1.O=C1c2sc(-c3ccc(Cl)cc3)nc2CCN1c1ccc2[nH]ccc2c1>>O=C1c2sc(-c3ccc(Cl)cc3)nc2CCN1c1ccc2c(ccn2Cc2ccccn2)c1 -US05061804,9,N.O=C(O)COC[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1>>NC(=O)COC[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1 -US20100261719A1,8,CC(=O)OCc1cc(CO)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F>>CC(=O)OCc1cc(C=O)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F -US20130230542A1,1,CC(C)Nc1ccccc1.OCCI>>CC(C)N(CCO)c1ccccc1 -US08236959B2,1,BrCc1ccccc1.CC(=O)c1ccc(O)c2ncccc12>>CC(=O)c1ccc(OCc2ccccc2)c2ncccc12 -US20080176830A1,3,Fc1cc(Br)cc(F)c1C(F)(F)F.O=C1Nc2ccc(Br)cc2CC1O>>O=C1Nc2ccc(-c3cc(F)c(C(F)(F)F)c(F)c3)cc2CC1O -US07074801B1,2,CC(C)(C)C(=O)Cl.Nc1cccc(N2CCN(c3ncnc4ccc(-c5cnn(C(c6ccccc6)(c6ccccc6)c6ccccc6)c5)cc34)CC2)c1>>CC(C)(C)C(=O)Nc1cccc(N2CCN(c3ncnc4ccc(-c5cnn(C(c6ccccc6)(c6ccccc6)c6ccccc6)c5)cc34)CC2)c1 -US06350741B1,2,Cc1cc(C(=O)O)cc(C)c1O.N[C@H]1CC(=O)c2ccccc2N(CC(=O)OCc2ccccc2)C1=O>>Cc1cc(C(=O)N[C@H]2CC(=O)c3ccccc3N(CC(=O)OCc3ccccc3)C2=O)cc(C)c1O -US08173650B2,6,C[C@H](O)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN(C(=O)OC(C)(C)C)C3)n(C)c2n1>>C[C@H](O)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1 -US08415381B2,3,C[C@H]1CC(CNc2cccc(Br)n2)C[C@@H](C)O1.OB(O)c1cc(F)ncc1Cl>>C[C@H]1CC(CNc2cccc(-c3cc(F)ncc3Cl)n2)C[C@@H](C)O1 -US05235091,3,O=C(O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1>>O=C(O)CCCCC=Cc1ccccc1 -US08318949B2,1,CCOC(=O)c1sc(N2CCNC2=O)nc1C.Fc1ccc(CBr)cc1>>CCOC(=O)c1sc(N2CCN(Cc3ccc(F)cc3)C2=O)nc1C -US20110319378A1,9,BrC(Br)(Br)Br.CCC(O)c1cccc(Cl)n1>>CCC(Br)c1cccc(Cl)n1 -US20130261101A1,1,CC(Cl)c1cc(Cl)c(C#N)c2c1OCCN(C(=O)OC(C)(C)C)C2.Cc1n[nH]c2ncnc(N)c12>>Cc1nn(C(C)c2cc(Cl)c(C#N)c3c2OCCN(C(=O)OC(C)(C)C)C3)c2ncnc(N)c12 -US07192968B2,1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@@H]1OS(C)(=O)=O.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N=[N+]=[N-] -US20150051395A1,2,COC(=O)[C@@H](N)Cc1ccc(-n2c(=O)ccn(C)c2=O)cc1.O=C(O)c1c(F)cc(NS(=O)(=O)c2ccc(-n3cccc3)cc2)cc1F>>COC(=O)[C@H](Cc1ccc(-n2c(=O)ccn(C)c2=O)cc1)NC(=O)c1c(F)cc(NS(=O)(=O)c2ccc(-n3cccc3)cc2)cc1F -US20070003680A1,9,BrCc1ccc(Br)nc1.[C-]#N>>N#CCc1ccc(Br)nc1 -US20120270856A1,2,CNCCCN(C)C.O=C(O)c1cnc(Cl)c(Cl)c1>>CN(C)CCCN(C)C(=O)c1cnc(Cl)c(Cl)c1 -US20150252008A1,1,CCCc1ccc(-c2cnc(N)cn2)c(F)c1O.Clc1ncccn1>>CCCc1ccc(-c2cnc(N)cn2)c(F)c1Oc1ncccn1 -US20070054909A1,2,COC(=O)c1ccc(OC[C@@H]2CC[C@H](c3ccccc3)N2)cc1.Cc1cc(CC(=O)O)ccc1NC(=O)Nc1ccccc1Br>>COC(=O)c1ccc(OC[C@@H]2CC[C@H](c3ccccc3)N2C(=O)Cc2ccc(NC(=O)Nc3ccccc3Br)c(C)c2)cc1 -US04810283,1,COC(=O)C(C)Br.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl>>COC(=O)C(C)Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl -US07105671B2,9,CS(=O)(=O)c1ccc([C@@H](CC2CCC(=O)CC2)C(=O)Nc2cnc(Br)cn2)cc1Cl.NO>>CS(=O)(=O)c1ccc([C@@H](CC2CCC(=NO)CC2)C(=O)Nc2cnc(Br)cn2)cc1Cl -US20070060658A1,2,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.[N-]=[N+]=NCCCN>>CN(C)c1cccc2c(S(=O)(=O)NCCCN=[N+]=[N-])cccc12 -US05434150,7,COC(=O)CCNC(=O)c1ccc2c(c1)nc(-c1ccc(C#N)cc1)n2CCCN>>COC(=O)CCNC(=O)c1ccc2c(c1)nc(-c1ccc(CN)cc1)n2CCCN -US06630483B2,7,COc1ccc([C@@H]2CCCC[C@@H]2[N+](=O)[O-])cc1OC>>COc1ccc([C@@H]2CCCC[C@@H]2N)cc1OC -US20100137298A1,6,Cc1c(C(=O)OC(C)(C)C)oc2cccc(-c3ccoc3)c12>>Cc1c(C(=O)O)oc2cccc(-c3ccoc3)c12 -US05539112,6,CC(=O)N(CCCCCCBr)c1ccc(-c2cc(=O)c3c(N)c(F)cc(F)c3o2)cc1F>>Nc1c(F)cc(F)c2oc(-c3ccc(NCCCCCCBr)c(F)c3)cc(=O)c12 -US06100398,1,CCCCNCCCC.Cc1ccc(Cl)cc1>>CCCCN(CCCC)c1ccc(C)cc1 -US20020193398A1,6,CCOC(=O)Cc1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1F>>O=C(O)Cc1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1F -US20020037931A1,6,COc1cc2c(c([N+](=O)[O-])c1O)C(=O)c1ccccc1C2=O>>O=C1c2ccccc2C(=O)c2c1cc(O)c(O)c2[N+](=O)[O-] -US20060058308A1,3,CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(Cl)n3)cccc2s1.OB(O)c1ccncc1>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(-c4ccncc4)n3)cccc2s1 -US08524917B2,1,CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(O)cc2n1Cc1ncco1.CCCI>>CCCOc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ncco3)c2c1 -US20090197935A1,6,CC(=O)Nc1ccc(OCC(C)(C)[N+](=O)[O-])c(-c2ccnn2C)c1>>Cn1nccc1-c1cc(N)ccc1OCC(C)(C)[N+](=O)[O-] -US05082838,1,Cc1ccc(CCl)cc1.O=c1[nH]c(=O)n2c(c1-c1ccccc1)SC=CC2>>Cc1ccc(Cn2c(=O)c(-c3ccccc3)c3n(c2=O)CC=CS3)cc1 -US06586424B2,1,CN1CCNCCC1=O.N#Cc1cnc(Nc2cc(CCl)ccn2)s1>>CN1CCN(Cc2ccnc(Nc3ncc(C#N)s3)c2)CCC1=O -US08697693B2,3,CN1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)c2cc[nH]c12>>Cc1ccc(-c2nc(N3CCOCC3)c3sc(CN4CCN(C)CC4)cc3n2)c2cc[nH]c12 -US08987295B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H]1Cc2cc(O)c(O)cc2CN1>>COC(=O)[C@@H]1Cc2cc(O)c(O)cc2CN1C(=O)OC(C)(C)C -US04076717,8,N#CC(CCN1CCC(C(=O)O)(c2ccccc2)CC1)(c1ccccc1)c1ccccc1.O=C(OO)c1cccc(Cl)c1>>N#CC(CC[N+]1([O-])CCC(C(=O)O)(c2ccccc2)CC1)(c1ccccc1)c1ccccc1 -US04350822,1,CCOC(=O)c1ccc(N)cc1.COc1ccccc1CCCBr>>CCOC(=O)c1ccc(NCCCc2ccccc2OC)cc1 -US07329679B2,1,COC(=O)CCCCCBr.Cc1ccc(Nc2cc(O)c([N+](=O)[O-])cc2[N+](=O)[O-])cc1C>>COC(=O)CCCCCOc1cc(Nc2ccc(C)c(C)c2)c([N+](=O)[O-])cc1[N+](=O)[O-] -US20090088419A1,2,Cc1ccc(-c2c(CC(=O)O)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1.O=C1COCC2CNCCN12>>Cc1ccc(-c2c(CC(=O)N3CCN4C(=O)COCC4C3)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1 -US07160889B2,1,BrCC1CO1.COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1O>>COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CO1 -US20110190137A1,6,CCOC(=O)CCC1(Br)CC1(Br)Br>>O=C(O)CCC1(Br)CC1(Br)Br -US05597832,7,CCCc1nc(C(=O)OC)c(Br)o1>>CCCc1nc(CO)c(Br)o1 -US20060223801A1,1,Brc1nccs1.Cc1[nH]c(C(=O)NC2CCNCC2)c(Cl)c1Cl>>Cc1[nH]c(C(=O)NC2CCN(c3nccs3)CC2)c(Cl)c1Cl -US20130060033A1,3,Brc1cccc(I)c1.OB(O)c1cccc(-c2cc(-c3ccccc3)cc3c2sc2ccc(-c4ccccc4)cc23)c1>>Brc1cccc(-c2cccc(-c3cc(-c4ccccc4)cc4c3sc3ccc(-c5ccccc5)cc34)c2)c1 -US04927928,1,CC1(c2cc(Br)ccc2O)CCCCC1.CI>>COc1ccc(Br)cc1C1(C)CCCCC1 -US08242145B2,3,CCOC(=O)Cc1cccc(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1.Cc1nc(Br)cn1C>>CCOC(=O)Cc1cccc(Oc2ccc(-c3cn(C)c(C)n3)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1 -US20080287455A1,2,CC(C)CSc1ccc(S(C)(=O)=O)cc1C(=O)O.Fc1cc(C(F)(F)F)cnc1N1CCNCC1>>CC(C)CSc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(C(F)(F)F)cc2F)CC1 -US20050203087A1,2,CCN(CC)C(=O)Cl.COC(=O)c1sc(-c2cccc(N)c2)c(Br)c1OCC(=O)OC(C)(C)C>>CCN(CC)C(=O)Nc1cccc(-c2sc(C(=O)OC)c(OCC(=O)OC(C)(C)C)c2Br)c1 -US08809536B2,7,O=C([C@H]1COc2ccccc2O1)N1CCC[C@@H](c2ccc(C(F)(F)F)cc2)C1>>FC(F)(F)c1ccc([C@@H]2CCCN(C[C@H]3COc4ccccc4O3)C2)cc1 -US05045105,5,O=Cc1cc([N+](=O)[O-])ccc1Cl.SCCS>>O=[N+]([O-])c1ccc(Cl)c(C2SCCS2)c1 -US06300363B1,2,CC(=O)Cl.CCOC(=O)n1c(C(=O)c2ccccc2)c(N)c2ccc(Cl)cc21>>CCOC(=O)n1c(C(=O)c2ccccc2)c(NC(C)=O)c2ccc(Cl)cc21 -US07371743B2,2,O=C(O)COCCNc1ccc(C(=O)O)cc1F>>O=C(O)c1ccc(N2CCOCC2=O)c(F)c1 -US05006520,1,O=C(CCl)N1CCOCC1.Oc1cccc(-n2nc(-c3ccc(F)cc3)c3cccnc32)c1>>O=C(COc1cccc(-n2nc(-c3ccc(F)cc3)c3cccnc32)c1)N1CCOCC1 -US05036088,1,Nc1ccc2[nH]c(=O)oc2c1.O=CCCc1ccccc1>>O=c1[nH]c2ccc(NCCCc3ccccc3)cc2o1 -US04608389,1,CCOC(=O)NCCCl.Oc1ccc(Oc2cc(F)cc(F)c2)cc1>>CCOC(=O)NCCOc1ccc(Oc2cc(F)cc(F)c2)cc1 -US05622976,1,CC(C)(C)OC(=O)N1CCC(CCOS(C)(=O)=O)CC1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCC(CCN2C(=O)c3ccccc3C2=O)CC1 -US20030073833A1,7,CC(=O)OCCc1c([N+](=O)[O-])ccc(NC(=O)C(F)(F)c2ccccc2)c1F>>CC(=O)OCCc1c(N)ccc(NC(=O)C(F)(F)c2ccccc2)c1F -US05416066,2,C=CC(=O)Cl.COc1ccc2c(c1)CNCCS2>>C=CC(=O)N1CCSc2ccc(OC)cc2C1 -US20100227859A1,6,COC(=O)[C@H](NS(=O)(=O)c1ccc2sc3cc(-c4ccc(Cl)o4)ccc3c2c1)C(C)C>>CC(C)[C@@H](NS(=O)(=O)c1ccc2sc3cc(-c4ccc(Cl)o4)ccc3c2c1)C(=O)O -US07683185B2,6,COC(=O)CCCCCSc1ccc(-c2ccc(Cl)cc2)cc1>>O=C(O)CCCCCSc1ccc(-c2ccc(Cl)cc2)cc1 -US20090176980A1,7,CCC=C(CCC)c1cnc(-c2c(CC)cccc2CC)cc1OC>>CCCC(CCC)c1cnc(-c2c(CC)cccc2CC)cc1OC -US20100041657A1,2,COc1cc2ccccc2cc1C(=O)O.Nc1cccc(S(=O)(=O)C(F)(F)F)c1>>COc1cc2ccccc2cc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 -US05578620,9,[N-]=[N+]=NCC(O)COCCCCCCc1ccccc1>>NCC(O)COCCCCCCc1ccccc1 -US04168964,1,COC(=O)NN.Cc1[nH]c(-c2cccc(C(F)(F)F)c2)nc1C=O>>COC(=O)NN=Cc1nc(-c2cccc(C(F)(F)F)c2)[nH]c1C -US20110190257A1,7,CCOC(=O)C(C)(C)ONC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NOC(C)(C)CO -US20120046292A1,6,CCOC(=O)[C@@H]1CC[C@H](Oc2ccc(C(=O)NCCNC(=O)OC(C)(C)C)cc2)CC1>>CCOC(=O)[C@@H]1CC[C@H](Oc2ccc(C(=O)NCCN)cc2)CC1 -US20070219235A1,6,CC(C)(C)OC(=O)Nc1ccccc1C1CCCCC1>>Nc1ccccc1C1CCCCC1 -US08293902B2,6,COc1cc2ncnc(Oc3ccc4[nH]ccc4c3F)c2cc1OCC1CCN(C(=O)OC(C)(C)C)CC1>>COc1cc2ncnc(Oc3ccc4[nH]ccc4c3F)c2cc1OCC1CCNCC1 -US06803381B1,2,Nc1nnco1.O=C(O)C(c1ccccc1)c1ccccc1>>O=C(Nc1nnco1)C(c1ccccc1)c1ccccc1 -US20050107400A1,6,CCOC(OCC)(OCC)c1ccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nn2c1>>CCOC(=O)c1ccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nn2c1 -US20090047246A1,1,BrCC1CC1.O=C(O)Cc1c(C(=O)c2ccccc2-c2ccccc2)[nH]c2ccccc12>>O=C(O)Cc1c(C(=O)c2ccccc2-c2ccccc2)n(CC2CC2)c2ccccc12 -US20150025068A1,2,CCC(O)COC.O=C(O)c1ccc(NS(=O)(=O)c2cc(-c3ccccc3)c(Cl)s2)cc1O>>CCC(COC)OC(=O)c1ccc(NS(=O)(=O)c2cc(-c3ccccc3)c(Cl)s2)cc1O -US20080188503A1,1,Cc1ncc(-c2nc(Br)ncc2F)n1C1CCOCC1.NC1CCN(Cc2ccccc2)CC1>>Cc1ncc(-c2nc(NC3CCN(Cc4ccccc4)CC3)ncc2F)n1C1CCOCC1 -US20050234101A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.OCCn1ncc2cc(I)ccc21>>OCCn1ncc2cc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)ccc21 -US08507473B2,1,NC1CCOCC1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>O=[N+]([O-])c1ccc(Cl)nc1NC1CCOCC1 -US05332736,6,CCOC(=O)Cc1cc(C)c(C(=O)c2ccc(Cl)cc2Cl)n1C>>Cc1cc(CC(=O)O)n(C)c1C(=O)c1ccc(Cl)cc1Cl -US08765960B2,7,C=C(c1ccc2c(c1)sc(=O)n2COC)c1ccn[nH]1>>COCn1c(=O)sc2cc(C(C)c3ccn[nH]3)ccc21 -US08129376B2,6,Cc1ccc(C#N)cc1OCc1ccccc1>>Cc1ccc(C#N)cc1O -US07105544B2,2,CCCC(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.O=C(O)C(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCC(=O)Nc1cccc(C2CCN(CCCNC(=O)C(c3ccccc3)(c3ccccc3)c3ccccc3)CC2)c1 -US06166006,6,COC(=O)C1=Cc2cc(-c3ccc(F)cc3)ccc2OCC1>>O=C(O)C1=Cc2cc(-c3ccc(F)cc3)ccc2OCC1 -US05631373,9,O=c1[nH]c2cc(F)c(F)c([N+](=O)[O-])c2[nH]c1=O.[NH4+]>>Nc1c(F)cc2[nH]c(=O)c(=O)[nH]c2c1[N+](=O)[O-] -US08853246B2,2,COC(=O)CN.O=C(O)c1cccnc1>>COC(=O)CNC(=O)c1cccnc1 -US20110294792A1,9,BrC(Br)(Br)Br.O=C1NC(=O)C(c2ccc(OCCCO)c3ccoc23)=C1c1cn2c3c(cccc13)CCC2>>O=C1NC(=O)C(c2ccc(OCCCBr)c3ccoc23)=C1c1cn2c3c(cccc13)CCC2 -US07196085B2,2,O=C(CC(C(=O)O)c1ccccc1)Nc1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C1CC(c2ccccc2)C(=O)N1c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F -US20070203155A1,6,COc1ccc(-c2nc(C)sc2Br)cc1>>Cc1nc(-c2ccc(O)cc2)c(Br)s1 -US08012979B2,1,C=O.Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CN3CCN[C@@H](CO)C3)c2c1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CN3CCN(C)[C@@H](CO)C3)c2c1 -US20060069128A1,2,CN.COC(=O)c1cc(C(=O)Cl)cc([N+](=O)[O-])c1>>CNC(=O)c1cc(C(=O)OC)cc([N+](=O)[O-])c1 -US05972946,1,CCCN(CCC)C(=O)CN.Cc1nc(-c2ccccc2)nc(Cl)c1C>>CCCN(CCC)C(=O)CNc1nc(-c2ccccc2)nc(C)c1C -US20060264622A1,6,COC(=O)CCCOc1cc([N+](=O)[O-])c(CO)cc1OC>>COc1cc(CO)c([N+](=O)[O-])cc1OCCCC(=O)O -US20080300242A1,3,COc1cc(Cl)ccc1[N+](=O)[O-].OB(O)c1ccncc1>>COc1cc(-c2ccncc2)ccc1[N+](=O)[O-] -US07015218B1,2,CC(C)(C)COc1ccc(N)cc1C#N.Cc1c(C(=O)O)cnn1C(C)(C)C>>Cc1c(C(=O)Nc2ccc(OCC(C)(C)C)c(C#N)c2)cnn1C(C)(C)C -US07326791B2,8,CSCC[C@H](NC(=O)c1ccc(C(=O)N2CCCC2)c(C)c1)c1nc2cc(Cl)ccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C(=O)N[C@@H](CCS(C)=O)c2nc3cc(Cl)ccc3[nH]2)ccc1C(=O)N1CCCC1 -US20150105366A1,1,C1CNC1.Cc1ccc(C(O)(c2ccc3nc(Cl)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)c2cnnn2C)c(C)n1>>Cc1ccc(C(O)(c2ccc3nc(N4CCC4)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)c2cnnn2C)c(C)n1 -US20120178736A1,1,Cc1nc2ccccc2[nH]1.Cn1c(CCN2CCN(C(C)(C)C(N)=O)CC2)nc2c(N3CCOCC3)nc(Cl)nc21>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CCN3CCN(C(C)(C)C(N)=O)CC3)n(C)c2n1 -US20130261101A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC(O)CN>>CCC(O)CNC(=O)OC(C)(C)C -US20150005286A1,1,FCC1CNC1.OCCBr>>OCCN1CC(CF)C1 -US20140315881A1,2,Cc1ccc(C(N)c2ccccc2)c(C)c1.Cc1noc(C)c1-c1nc2cc(CC(=O)O)ccc2o1>>Cc1ccc(C(NC(=O)Cc2ccc3oc(-c4c(C)noc4C)nc3c2)c2ccccc2)c(C)c1 -US05736564,6,CCCOc1ccc(C(=O)c2ccc3c(c2)OCO3)c(C(=O)c2ccc(OC)cc2OCc2ccccc2)c1>>CCCOc1ccc(C(=O)c2ccc3c(c2)OCO3)c(C(=O)c2ccc(OC)cc2O)c1 -US20140275030A1,7,Cc1noc(C)c1-c1cc(C=O)c2[nH]c(=O)n3c2c1OC[C@@H]3c1ccccn1>>Cc1noc(C)c1-c1cc(CO)c2[nH]c(=O)n3c2c1OCC3c1ccccn1 -US20120101051A1,2,CC(=O)CN.O=C(O)c1ccc(Cc2cc([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)nn1>>CC(=O)CNC(=O)c1ccc(Cc2cc([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)nn1 -US20110118231A1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1ccccc1C=O>>CCOC(=O)/C=C/c1ccccc1C#N -US05066822,4,CC(C)(C)c1cc(OCCCCC#N)cc(C(C)(C)C)c1O.[N-]=[N+]=[N-]>>CC(C)(C)c1cc(OCCCCc2nnn[nH]2)cc(C(C)(C)C)c1O -US20140275035A1,1,CCOC(=O)N1CCc2sc3cc[nH]c3c2CC1.Ic1ccccc1>>CCOC(=O)N1CCc2sc3ccn(-c4ccccc4)c3c2CC1 -US07129268B2,6,COC(=O)COc1ccc(SCC=C(c2ccc(I)cc2)c2ccc(I)cc2)cc1OC>>COc1cc(SCC=C(c2ccc(I)cc2)c2ccc(I)cc2)ccc1OCC(=O)O -US20090082434A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1Cc2cccc(C3CCCC3)c2O1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(C4CCCC4)c3O2)cc1 -US20080114044A1,6,COC(=O)Cc1ccc(-c2onc(-c3ccccc3)c2C(=O)NCCOc2ccc(Cl)cc2Cl)c(Cl)c1>>O=C(O)Cc1ccc(-c2onc(-c3ccccc3)c2C(=O)NCCOc2ccc(Cl)cc2Cl)c(Cl)c1 -US20120258946A1,6,CC(C)(C)OC(=O)NCc1cc(C(F)(F)F)nn1-c1cc(F)cc(F)c1>>NCc1cc(C(F)(F)F)nn1-c1cc(F)cc(F)c1 -US04535186,7,N#CC(c1ccc(Cl)cc1)C1(O)CCCCC1>>NCC(c1ccc(Cl)cc1)C1(O)CCCCC1 -US07956083B2,1,Brc1ccc(OCc2ccccc2)cc1.c1ccc(COc2cccc3[nH]ccc23)cc1>>c1ccc(COc2ccc(-n3ccc4c(OCc5ccccc5)cccc43)cc2)cc1 -US04923880,5,COC(=O)N1CC(C)C(=O)C(C#N)C1.OCCO>>COC1(N2CC(C)C(=O)C(C#N)C2)OCCO1 -USRE030241,2,CC(C)NCC(=O)c1ccc(O)c(O)c1.O=C(Cl)c1cccc2ccccc12>>CC(C)NCC(=O)c1ccc(OC(=O)c2cccc3ccccc23)c(O)c1 -US08354444B2,6,COC(=O)Cc1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(CC(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20110034433A1,6,N#Cc1ccc(C2OCCCO2)c(S(=O)(=O)CCO)c1>>N#Cc1ccc(C=O)c(S(=O)(=O)CCO)c1 -US08889702B2,1,CCOC(=O)c1cc(COC(=O)NC2CC3(CCNC3)C2)on1.Fc1ccc(-c2ccc(F)nc2)cc1>>CCOC(=O)c1cc(COC(=O)NC2CC3(CCN(c4ccc(-c5ccc(F)cc5)cn4)C3)C2)on1 -US20080113963A1,2,CN.Cc1nc2c3c(c(C(=O)O)cc2n1C)CCC(c1ccccc1)O3>>CNC(=O)c1cc2c(nc(C)n2C)c2c1CCC(c1ccccc1)O2 -US20090253723A1,2,Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(CCN4CCOCC4)c3)n2)c1.O=C(Cl)c1ccccc1F>>O=C(Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(CCN4CCOCC4)c3)n2)c1)c1ccccc1F -US20070111926A1,2,CC(C)(C)OC(=O)CCC(=O)[O-].NCc1cccc(CO)c1>>CC(C)(C)OC(=O)CCC(=O)NCc1cccc(CO)c1 -US09139559B2,2,CNC1CCN(Cc2ccccc2)CC1.Cc1nc(NCC(=O)O)nc(C)c1[N+](=O)[O-]>>Cc1nc(NCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1[N+](=O)[O-] -US20110301155A1,1,CC(=O)N1CCNCC1.O=Cc1cnc(Nc2n[nH]c3ccc(-c4ncccc4Cl)cc23)s1>>CC(=O)N1CCN(Cc2cnc(Nc3n[nH]c4ccc(-c5ncccc5Cl)cc34)s2)CC1 -US20120178736A1,1,Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CBr)n(C)c2n1.N#CC1CCNCC1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C#N)CC3)n(C)c2n1 -US20090215776A1,1,C=O.CC1CN(C(=O)OCc2ccccc2)CC(C)N1>>CC1CN(C(=O)OCc2ccccc2)CC(C)N1C -US20100048536A1,6,COC(=O)c1ccccc1C(=O)N(C)c1cccc(OC)c1>>COc1cccc(N(C)C(=O)c2ccccc2C(=O)O)c1 -US08273766B2,2,COc1ccc(N=C=O)cc1.NCCCN1Cc2ccccc2CC1Cc1ccc(F)cc1>>COc1ccc(NC(=O)NCCCN2Cc3ccccc3CC2Cc2ccc(F)cc2)cc1 -US20070049632A1,1,C=CCI.CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccc(F)cc3F)c(=O)c12>>C=CCn1c2c(c(=O)n1-c1ccc(F)cc1F)[C@H]1CC[C@]2(C)C1(C)C -US06951879B2,1,BrCCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1.CNC>>CN(C)CCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1 -US07067658B2,1,CC[C@@H](N)C1CC1.COc1cc(C)c(-c2ccnc(OS(=O)(=O)C(F)(F)F)c2[N+](=O)[O-])cc1F>>CC[C@@H](Nc1nccc(-c2cc(F)c(OC)cc2C)c1[N+](=O)[O-])C1CC1 -US20100210635A1,6,COC(=O)CCc1ccccc1Oc1ccccc1CCC(=O)N1CCN(C(=O)OC(C)(C)C)C[C@H]1Cc1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=O)CCc2ccccc2Oc2ccccc2CCC(=O)O)[C@H](Cc2ccccc2)C1 -US06482829B2,1,ClCCN1CCCC1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)NCN2c1ccccc1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)N(CCN1CCCC1)CN2c1ccccc1 -US20060264490A1,6,CC(=O)N(C)c1ccc2c(c1)nc(C(C)(F)F)n2CC1CCOCC1>>CNc1ccc2c(c1)nc(C(C)(F)F)n2CC1CCOCC1 -US20150099882A1,1,CCOC(=O)c1ccc(C(CC(C)C)OS(C)(=O)=O)cc1.Cc1nc2ccccc2cc1N>>CCOC(=O)c1ccc(C(CC(C)C)Nc2cc3ccccc3nc2C)cc1 -US06207693B1,6,COc1cc(C(=O)N(C)c2ccc(C)cc2OCc2ccccc2)ccc1NC(=O)c1cccc2[nH]c(CNC(=O)OC(C)(C)C)nc12>>COc1cc(C(=O)N(C)c2ccc(C)cc2OCc2ccccc2)ccc1NC(=O)c1cccc2[nH]c(CN)nc12 -US20080318937A1,4,CC(C)(C)OC(=O)N1CCC(N2c3ccccc3Oc3cc(C#N)ccc32)CC1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC(N2c3ccccc3Oc3cc(-c4nnn[nH]4)ccc32)CC1 -US06723741B2,7,O=[N+]([O-])c1cc(Br)c2[nH]ccc2c1>>Nc1cc(Br)c2[nH]ccc2c1 -US20110009454A1,1,CN.Nc1nc(Cl)ccc1C(=O)NCc1ccc(Oc2ccccc2)cc1>>CNc1ccc(C(=O)NCc2ccc(Oc3ccccc3)cc2)c(N)n1 -US20100190778A1,1,CCN1Cc2ccccc2S(=O)(=O)N1.CI>>CCN1Cc2ccccc2S(=O)(=O)N1C -US05556864,1,CN1CCCC1CCCl.COc1ccccc1CCc1ccccc1O>>COc1ccccc1CCc1ccccc1OCCC1CCCN1C -US20040214832A1,1,NCc1ccccc1.O=C(CCl)Nc1ccc(OCc2ccccc2)cc1>>O=C(CNCc1ccccc1)Nc1ccc(OCc2ccccc2)cc1 -US05344843,2,O=C(O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1.OCC(O)CO>>O=C(OCC(O)CO)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1 -US04048306,6,CCOC(OCC)C(O)C(C)=O>>CC(=O)C(O)C=O -US20060034796A1,9,CC1(C)CCC2=C(O1)c1ccccc1C1(OCC(CN=[N+]=[N-])O1)C2=O>>CC1(C)CCC2=C(O1)c1ccccc1C1(OCC(CN)O1)C2=O -US20090239880A1,1,Clc1nc2ccccc2[nH]1.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>Fc1ccc(C(c2ccc(F)cc2)N2CCN(c3nc4ccccc4[nH]3)CC2)cc1 -US07495007B2,1,CC(C)(C)OC(=O)CBr.Cc1ccc(F)cc1C1CC(=O)NC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1CC(=O)N(CC(=O)OC(C)(C)C)C(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12 -US06602863B1,2,C/C=C/C(=O)Cl.Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1>>C/C=C/C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 -US20060034909A1,9,CCCCCCCCCCCCCCCCCC[Si](C)(C)Cl>>CCCCCCCCCCCCCCCCCC[SiH](C)C -US20130095123A1,2,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)CS(=O)(=O)Cc1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)O)C(C)C.NNC(=O)CCCCCN1C(=O)C=CC1=O>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)CS(=O)(=O)Cc1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)NNC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C -US04129653,2,CCOC(=O)Cl.CCOC(=O)c1cc2n(c1)CNc1ccccc1-2>>CCOC(=O)c1cc2n(c1)CN(C(=O)OCC)c1ccccc1-2 -US06127414,2,C[C@@H](NC(=O)[C@@H](N)CCCNC(=O)OCc1ccccc1)c1ccc(O)cc1.O=C(O)C(c1ccccc1)c1ccccc1>>C[C@@H](NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)C(c1ccccc1)c1ccccc1)c1ccc(O)cc1 -US04525361,7,COc1cc(C)c(C(=O)CCC(=O)O)c(O)c1OC>>COc1cc(C)c(CCCC(=O)O)c(O)c1OC -US07169777B2,7,CC(C)(C)OC(=O)N1CCN(C(C#N)c2ccccc2F)CC1>>CC(C)(C)OC(=O)N1CCN(C(CN)c2ccccc2F)CC1 -US20140323463A1,1,CC(C)(C)OC(=O)N1CCC(O)C1.CCc1nc(C(N)=O)c(Cl)nc1Cl>>CCc1nc(C(N)=O)c(Cl)nc1OC1CCN(C(=O)OC(C)(C)C)C1 -US08269011B2,1,CCCS.O=[N+]([O-])c1cc(F)ccc1F>>CCCSc1ccc(F)cc1[N+](=O)[O-] -US20110212053A1,1,C1COCCN1.CC(C)(C#N)c1ccc(Cc2c([N+](=O)[O-])cnc3ccc(Br)cc23)cc1>>CC(C)(C#N)c1ccc(Cc2c([N+](=O)[O-])cnc3ccc(N4CCOCC4)cc23)cc1 -US05952355,2,COc1cc(C(=O)/C=C/c2c[nH]c3ccccc23)cc(OC)c1OC.O=S(=O)(Cl)c1ccccc1>>COc1cc(C(=O)/C=C/c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)cc(OC)c1OC -US20050165058A1,6,CC(C)(C)OC(=O)NCC1CCN(c2noc(C(Cl)(Cl)Cl)n2)CC1>>NCC1CCN(c2noc(C(Cl)(Cl)Cl)n2)CC1 -US20020028801A1,6,CC(C)CC(CNC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C)NC(=O)OC(C)(C)C>>CC(C)C[C@H](N)CN[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C -US20150166483A1,1,COCCOCCBr.COc1cc(SCCO)cc([N+](=O)[O-])c1>>COCCOCCOCCSc1cc(OC)cc([N+](=O)[O-])c1 -US05753595,1,CC(C)(C)c1nc2c(Cl)cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)c2o1.CI>>Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c3nc(C(C)(C)C)oc23)c1=O -US20070093484A1,1,CCCBr.COC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1O>>CCCOc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)OC -US07368578B2,6,CCOC(=O)c1cn(Cc2ccccc2)nc1OCc1ccc(OCc2nc(-c3ccco3)oc2C)c(-c2ccccc2)c1>>Cc1oc(-c2ccco2)nc1COc1ccc(COc2nn(Cc3ccccc3)cc2C(=O)O)cc1-c1ccccc1 -US20120309738A1,7,CNc1cc(N2CCC(C(F)(F)F)CC2)c(C#N)cc1[N+](=O)[O-]>>CNc1cc(N2CCC(C(F)(F)F)CC2)c(C#N)cc1N -US20100022592A1,4,N#CCOc1ccc(Nc2nc(-c3ccccc3Cl)cs2)cc1.[N-]=[N+]=[N-]>>Clc1ccccc1-c1csc(Nc2ccc(OCc3nnn[nH]3)cc2)n1 -US20140005168A1,3,CCCC[Sn](CCCC)(CCCC)c1cc2c(cn1)cnn2-c1cccc(F)n1.COc1ccc(CNc2cncc(Br)n2)cc1>>COc1ccc(CNc2cncc(-c3cc4c(cn3)cnn4-c3cccc(F)n3)n2)cc1 -US08952004B2,6,CCOC(=O)CC1CCN(c2ccccc2NC(=O)c2cccc(Cl)c2)CC1>>O=C(O)CC1CCN(c2ccccc2NC(=O)c2cccc(Cl)c2)CC1 -US20150025057A1,1,CCOC(=O)c1ccc(Cl)nc1.CN1CCC(O)C1>>CCOC(=O)c1ccc(OC2CCN(C)C2)nc1 -US20040254241A1,2,CCCCCCCCCCN.N#CCC(=O)O>>CCCCCCCCCCNC(=O)CC#N -US04585772,1,C=CCBr.O=C1Nc2ccc(OC(F)(F)F)cc2C2=NCCCN12>>C=CCN1C(=O)N2CCCN=C2c2cc(OC(F)(F)F)ccc21 -US08288413B2,1,CCOC(=O)N1CCC(N)CC1.O=[N+]([O-])c1ccc(Cl)cc1Cl>>CCOC(=O)N1CCC(Nc2cc(Cl)ccc2[N+](=O)[O-])CC1 -US08088815B2,6,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12 -US20080096861A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](Cn2c(CCl)nc3ccccc32)C1.CN[C@H]1CCCc2cccnc21>>CN(Cc1nc2ccccc2n1C[C@@H]1CCCN(C(=O)OC(C)(C)C)C1)[C@H]1CCCc2cccnc21 -US06013658,6,CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)c1nnc(C(N)=O)o1>>CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)c1nnc(C(N)=O)o1 -US20140155391A1,1,CSc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NS(C)(=O)=O.ClCCN1CCOCC1>>CSc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1N(CCN1CCOCC1)S(C)(=O)=O -US05131946,2,OCC1CCCCN1.S=C=Nc1ccccc1Cl>>OCC1CCCCN1C(=S)Nc1ccccc1Cl -US20100197668A1,6,COC(=O)c1cc(C(=O)N[C@@H](Cc2ccccc2)[C@H](O)CNC2(c3cccc(C(F)(F)F)c3)CC2)n2c1CN(C(=O)OC(C)(C)C)CC2>>CC(C)(C)OC(=O)N1CCn2c(C(=O)N[C@@H](Cc3ccccc3)[C@H](O)CNC3(c4cccc(C(F)(F)F)c4)CC3)cc(C(=O)O)c2C1 -US20110301142A1,3,CCOC(=O)Cc1ccc(B(O)O)cc1.Cc1noc(-c2ccc(CCl)cc2)c1NC(=O)O[C@H](C)c1ccccc1F>>CCOC(=O)Cc1ccc(Cc2ccc(-c3onc(C)c3NC(=O)O[C@H](C)c3ccccc3F)cc2)cc1 -US03953496,2,COc1ccccc1C(=O)Cl.COc1ccccc1C(=O)Nc1cc(N)ccc1C(=O)O>>COc1ccccc1C(=O)Nc1ccc(C(=O)O)c(NC(=O)c2ccccc2OC)c1 -US06331539B1,2,CCCCc1nc2c(N)nc3ccccc3c2n1CCCCN.O=S(=O)(Cl)Cc1ccccc1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCCNS(=O)(=O)Cc1ccccc1 -US20040121965A1,6,C/C(=C\[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)O>>C/C(=C\[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](N)Cc1cccc2ccccc12)C(C)(C)C)C(=O)O -US06780872B2,1,COC(=O)Cl.Cn1[nH]c(=O)c2c1NC1=C(C(=O)CC1)C2c1ccc(F)c(Br)c1>>COC(=O)n1c(=O)c2c(n1C)NC1=C(C(=O)CC1)C2c1ccc(F)c(Br)c1 -US08592399B2,3,COc1cc(C(=O)C=C(C)Br)cc(OC)c1OC.O=Cc1ccc(Br)cc1>>COc1cc(C(=O)C=C(C)c2ccc(C=O)cc2)cc(OC)c1OC -US08088815B2,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12.COC(=O)c1ccc(N)c(OC)c1>>COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c(OC)c1 -US05071844,2,COc1ccc(CC(=O)N2CCC[C@H]2C(=O)O)cc1.Nc1ccccc1SCc1ccccc1Br>>COc1ccc(CC(=O)N2CCC[C@H]2C(=O)Nc2ccccc2SCc2ccccc2Br)cc1 -US20130324576A1,6,COc1cc(Cl)ccc1CC1(O)CCN(C(=O)OC(C)(C)C)CC1>>COc1cc(Cl)ccc1CC1(O)CCNCC1 -US20110082278A1,6,CCCCCCc1c(C(=O)OCC)sc2ccsc12>>CCCCCCc1c(C(=O)O)sc2ccsc12 -US07176224B2,1,CCOC(=O)C(C)Br.Cc1ccc(O)cc1C>>CCOC(=O)C(C)Oc1ccc(C)c(C)c1 -US04988705,9,O=C(O)c1cccnc1Cl>>O=C(O)c1cccnc1 -US08394799B2,2,NCc1ccco1.O=C(O)c1ccc2[nH]c(COc3ccc(C45CC6CC(CC(C6)C4)C5)cc3)nc2c1>>O=C(NCc1ccco1)c1ccc2[nH]c(COc3ccc(C45CC6CC(CC(C6)C4)C5)cc3)nc2c1 -US07268133B2,1,CC(C)O.Clc1ccc(-c2c3ncnc(Cl)c3nn2-c2ccccc2Cl)cc1>>CC(C)Oc1ncnc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc12 -US20110245227A1,6,CS(=O)(=O)c1ccc(-n2ccc(OCc3ccccc3)cc2=O)c(F)c1>>CS(=O)(=O)c1ccc(-n2ccc(O)cc2=O)c(F)c1 -US20100240658A1,6,COCc1ccccc1-c1ccc(C(=O)OC)cc1C>>COCc1ccccc1-c1ccc(C(=O)O)cc1C -US20150266916A1,7,CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCc4ccccc4)cc3)c2)O[C@](C=O)(CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCc4ccccc4)cc3)c2)OC(CO)(CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US20140315898A1,1,CN(C)C(=O)c1ccco1.Cc1cc(F)c(N)cc1SCC(F)(F)F>>Cc1cc(F)c(N=C(c2ccco2)N(C)C)cc1SCC(F)(F)F -US20100204246A1,1,N[C@@H](CO)c1ccc(F)cn1.O=[N+]([O-])c1cc(F)c(F)nc1F>>O=[N+]([O-])c1cc(F)c(F)nc1N[C@@H](CO)c1ccc(F)cn1 -US08470816B2,2,CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1.O=C1CC(C(=O)O)CC(=O)N1>>CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(C(=O)C2CC(=O)NC(=O)C2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US06110933,2,CCCCCCCCCCCCC[C@@H](O)CC(N)=O.CS(=O)(=O)Cl>>CCCCCCCCCCCCC[C@H](CC(N)=O)OS(C)(=O)=O -US05385692,7,CCCCCCCCC1Cc2ccccc2C1=O>>CCCCCCCCC1Cc2ccccc2C1 -US07001897B2,2,COC1CN(C(=O)c2coc(N3CC(O)C3)n2)C1.CS(=O)(=O)Cl>>COC1CN(C(=O)c2coc(N3CC(OS(C)(=O)=O)C3)n2)C1 -US20100029745A1,1,CCOC(=O)C(C)(C)Oc1ccc(CCC(O)c2ccc(-c3cccc(C(F)(F)F)c3)s2)c(Cl)c1Cl.CI>>CCOC(=O)C(C)(C)Oc1ccc(CCC(OC)c2ccc(-c3cccc(C(F)(F)F)c3)s2)c(Cl)c1Cl -US08895313B2,1,CNC.Cc1ccc2nc(-c3ccc(NC(=O)c4ccc(Cl)nc4)cc3)cn2c1>>Cc1ccc2nc(-c3ccc(NC(=O)c4ccc(N(C)C)nc4)cc3)cn2c1 -US07557127B2,6,CCOC(=O)/C=C/c1ccc(NC2CCN(Cc3ccccc3)C2)nc1>>O=C(O)/C=C/c1ccc(NC2CCN(Cc3ccccc3)C2)nc1 -US04775671,1,COc1ccc(C=O)c(OC)c1.NCC(=O)O>>COc1ccc(CNCC(=O)O)c(OC)c1 -US06586475B1,6,CC(C)(C)OC(=O)NCCNC(=O)Cc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1>>NCCNC(=O)Cc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1 -US20090304734A1,6,CC(=O)O[C@H]1[C@H](OC(C)=O)[C@@H](CO[Si](C)(C)C(C)(C)C)O[C@H](OCCNC(=O)OCc2ccccc2)[C@H]1N=[N+]=[N-]>>CC(=O)O[C@H]1[C@H](OC(C)=O)[C@@H](CO)O[C@H](OCCNC(=O)OCc2ccccc2)[C@H]1N=[N+]=[N-] -US06156884,10,COC(=O)c1c(OC(C)=O)cc(C)cc1OC(C)=O.O=C1CCC(=O)N1Br>>COC(=O)c1c(OC(C)=O)cc(CBr)cc1OC(C)=O -US06982348B2,2,CC(F)(F)c1cccc(CC(N)C(O)c2ccc(F)cc2)c1.O=C(O)c1cccc2c1C=CCCC2>>CC(F)(F)c1cccc(CC(NC(=O)c2cccc3c2C=CCCC3)C(O)c2ccc(F)cc2)c1 -US20050192310A1,3,CC(=O)N1Cc2cnc(Cl)cc2C=Cc2ccccc21.COc1ccc(B2OC(C)(C)C(C)(C)O2)cn1>>COc1ccc(-c2cc3c(cn2)CN(C(C)=O)c2ccccc2C=C3)cn1 -US20090181942A1,8,COc1ccc(F)c(C(O)c2cc(Cl)ccc2-n2cccc2)c1OC>>COc1ccc(F)c(C(=O)c2cc(Cl)ccc2-n2cccc2)c1OC -US20150072969A1,6,CCOC(=O)CC1(c2ccc(OCc3ccc(F)c(OC(F)(F)F)c3)cc2)COC1>>O=C(O)CC1(c2ccc(OCc3ccc(F)c(OC(F)(F)F)c3)cc2)COC1 -US20040167155A1,2,CC(=O)OC(C)=O.Nc1ccccc1-c1ccc(Cl)cc1>>CC(=O)Nc1ccccc1-c1ccc(Cl)cc1 -US06878707B2,2,COC(=O)Cl.ClCCNCCCl>>COC(=O)N(CCCl)CCCl -US20140018368A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Nc1ccc(Cl)c(I)c1>>CC1(C)OB(c2cc(N)ccc2Cl)OC1(C)C -US07704995B2,3,CNC(=O)c1nc(Br)cnc1N.O=C(OCc1ccccc1)c1ccc(B(O)O)cc1>>CNC(=O)c1nc(-c2ccc(C(=O)OCc3ccccc3)cc2)cnc1N -US05081253,8,Fc1cccc(Cl)c1CSc1nc2cnccc2[nH]1.OO>>O=S(Cc1c(F)cccc1Cl)c1nc2cnccc2[nH]1 -US20110183976A1,1,COc1ccc(C2=C(c3ccc(O)cc3)COC2=O)cc1.Cc1cccc(CCl)n1>>COc1ccc(C2=C(c3ccc(OCc4cccc(C)n4)cc3)COC2=O)cc1 -US05607960,3,C=CC(O)(CC)CC.O=C(OCc1ccccc1)N1CCC[C@@H]1Cc1c[nH]c2ccc(Br)cc12>>CCC(O)(C=Cc1ccc2[nH]cc(C[C@H]3CCCN3C(=O)OCc3ccccc3)c2c1)CC -US20070003539A1,7,N#Cc1cccc(NC(=O)N2CC[C@H](O)C2)c1>>NCc1cccc(NC(=O)N2CC[C@H](O)C2)c1 -US20150018547A1,1,CCOC(=O)Cc1csc2cc(O)ccc12.Cn1nc(C(F)(F)F)cc1CO>>CCOC(=O)Cc1csc2cc(OCc3cc(C(F)(F)F)nn3C)ccc12 -US20040209939A1,7,Cc1cnc2c([N+](=O)[O-])cccc2n1>>Cc1cnc2c(N)cccc2n1 -US20070135595A1,10,Cc1cc(F)ccc1Br.O=C1CCC(=O)N1Br>>Fc1ccc(Br)c(CBr)c1 -US20060089367A1,2,Fc1cc2nc(COc3ccccc3)n(Cc3ccc(OC(F)(F)F)cc3)c2cc1N1CCNCC1.O=C(Cl)C1CC1>>O=C(C1CC1)N1CCN(c2cc3c(cc2F)nc(COc2ccccc2)n3Cc2ccc(OC(F)(F)F)cc2)CC1 -US20130158031A1,1,C(#Cc1ccc2ccccc2n1)c1ccc(-c2n[nH]cc2-c2ccncc2)cc1.CCBr>>CCn1cc(-c2ccncc2)c(-c2ccc(C#Cc3ccc4ccccc4n3)cc2)n1 -US20120259123A1,7,CCCCC(C)(C)c1ccc(C=O)c(F)c1>>CCCCC(C)(C)c1ccc(CO)c(F)c1 -US08975254B2,2,C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.O=C(O)c1[nH]nc2c1CCCC2>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1[nH]nc2c1CCCC2 -US05366987,6,CCOC(=O)C(C(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1>>CC(C)c1cccc(C(C)C)c1NC(=O)C(C(=O)O)c1ccccc1 -US04025630,1,CCCC(C)(c1ccccc1)c1cc(O)c2c(c1)OC(C)(C)C1=C2CCC1.O=C(O)CCCN1CCOCC1>>CCCC(C)(c1ccccc1)c1cc(OC(=O)CCCN2CCOCC2)c2c(c1)OC(C)(C)C1=C2CCC1 -US20150274664A1,1,CN(C)C(=O)Cc1c(F)cc(F)cc1F.O=C(OCc1ccccc1)N1CCC([C@H]2C[C@@H]2CCO)CC1>>CN(C)C(=O)Cc1c(F)cc(F)cc1OCC[C@H]1C[C@@H]1C1CCN(C(=O)OCc2ccccc2)CC1 -US20110288066A1,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CN(C)C(=O)c1cccc(Br)c1>>CN(C)C(=O)c1cccc(C#Cc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)c1 -US20140200344A1,8,Brc1cnc2[nH]ccc2c1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1cc(Br)cc2cc[nH]c21 -US20110015157A1,3,CON(C)C(=O)CNC(=O)OC(C)(C)C.C[Mg+]>>CC(=O)CNC(=O)OC(C)(C)C -US06291455B1,6,COc1cc2c(Nc3ccc(C)c(OC(C)=O)c3)ncnc2cc1OCc1ccccc1>>COc1cc2c(Nc3ccc(C)c(OC(C)=O)c3)ncnc2cc1O -US06326359B1,1,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN)nc32)[C@H](O)[C@@H]1O.COc1ccc(C=O)cc1OC>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CNCc4ccc(OC)c(OC)c4)nc32)[C@H](O)[C@@H]1O -US20140323519A1,1,C[Si](C)(C)CCOCCl.Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Br>>Cc1ccc(N(COCC[Si](C)(C)C)C(=O)c2cccc(C(C)(C)C#N)c2)cc1Br -US09120749B2,3,COc1cc(B2OC(C)(C)C(C)(C)O2)cc(Cl)c1O.O=C(c1cnc2ccc(Br)cc2c1N1CCC(CN2CCOCC2)CC1)C1CC1>>COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(N4CCC(CN5CCOCC5)CC4)c3c2)cc(Cl)c1O -US09040714B2,2,CN1CCC(N)CC1.Cc1nc(Br)sc1C(=O)O>>Cc1nc(Br)sc1C(=O)NC1CCN(C)CC1 -US20140066420A1,6,CCOC(=O)C(=O)N1CC(Oc2ccccc2C(C)(C)C)C1>>CC(C)(C)c1ccccc1OC1CN(C(=O)C(=O)O)C1 -US20150011528A1,6,CCOC(=O)Cn1c2c(sc1=NC(=O)c1cccc(C(F)(F)F)c1)CCCC2>>O=C(O)Cn1c2c(sc1=NC(=O)c1cccc(C(F)(F)F)c1)CCCC2 -US06727245B2,6,CC(=O)Nc1cccc(-n2c(=O)c(Cc3cccnc3)nc3cccnc32)c1>>Nc1cccc(-n2c(=O)c(Cc3cccnc3)nc3cccnc32)c1 -US06432993B1,2,Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(N)cc3)cc21.O=C(Cl)c1ccncc1>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(NC(=O)c4ccncc4)cc3)cc21 -US20150218144A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)c1nccc(C(O)CNCCO)n1>>CC(C)c1nccc(C(O)CN(CCO)C(=O)OC(C)(C)C)n1 -US04791200,1,ClCCCCOc1ccccc1-c1csc(-c2ccccc2)n1.c1c[nH]cn1>>c1ccc(-c2nc(-c3ccccc3OCCCCn3ccnc3)cs2)cc1 -US20080300266A1,6,CC(C)(C)OC(=O)N1CC[C@H](NCc2ccc(Cl)cc2Cl)C1>>Clc1ccc(CN[C@H]2CCNC2)c(Cl)c1 -US04332809,2,CCNc1ccc(-c2cc(OCC)cc(C(=O)O)n2)cc1.Nc1nnn[nH]1>>CCNc1ccc(-c2cc(OCC)cc(C(=O)Nc3nnn[nH]3)n2)cc1 -US20060281799A1,9,[N-]=[N+]=NC1CCc2cccc(NC(=O)OCc3ccccc3)c2C1>>NC1CCc2cccc(NC(=O)OCc3ccccc3)c2C1 -US08754077B2,7,C[C@@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3C=O)cn(C)c2=O)nc1>>C[C@@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3CO)cn(C)c2=O)nc1 -US20070293530A1,4,CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)CBr.COc1ccc(C(N)=S)cc1>>COc1ccc(-c2nc([C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)OCc3ccccc3)cs2)cc1 -US20060160794A1,6,CC(C)(C)[Si](C)(C)OC1CC(c2ccccc2Cl)N(C(=O)c2nnn(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2-c2cccnc2)C1>>O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1cccnc1)N1C[C@H](O)C[C@@H]1c1ccccc1Cl -US20130065876A1,6,CN(CCCO[Si](C)(C)C(C)(C)C)NC(=O)OC(C)(C)C>>CN(N)CCCO[Si](C)(C)C(C)(C)C -US04370328,1,COc1cc2cnnc(Cl)c2cc1OC.OCC1CCCNC1>>COc1cc2cnnc(N3CCCC(CO)C3)c2cc1OC -US04772600,2,CNC.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>CN(C)C(=O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21 -US05190974,6,CC(=O)SCC(Cc1ccccc1)NC(=O)N1CCN(c2ccc(Cl)cc2)CC1>>O=C(NC(CS)Cc1ccccc1)N1CCN(c2ccc(Cl)cc2)CC1 -US05648373,1,BrCCCCCCCn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1.CCOP(OCC)OCC>>CCOP(=O)(CCCCCCCn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1)OCC -US07279488B2,3,CC(=O)N1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1.COc1ccnc(CCc2nc3cc(I)cnc3[nH]2)c1>>COc1ccnc(CCc2nc3cc(-c4ccc(S(=O)(=O)N5CCN(C(C)=O)CC5)cc4)cnc3[nH]2)c1 -US04642311,1,CO.ClCCc1c[nH]c(-c2ccc(OCc3ccccc3)cc2)n1>>COCCc1c[nH]c(-c2ccc(OCc3ccccc3)cc2)n1 -US20150158863A1,1,CCC(Cl)C(=O)N1CC(=O)N(COCC[Si](C)(C)C)c2cccnc21.Oc1cccc(OC(F)(F)F)c1>>CCC(Oc1cccc(OC(F)(F)F)c1)C(=O)N1CC(=O)N(COCC[Si](C)(C)C)c2cccnc21 -US20140155445A1,1,O=C(CBr)CCc1ccc(Br)cc1.c1c[nH]cn1>>O=C(CCc1ccc(Br)cc1)Cn1ccnc1 -US05707985,2,CC(=O)Cl.O=S(=O)(c1ccc2c(c1)CCCN2)N1CC2CCC(CC2)C1>>CC(=O)N1CCCc2cc(S(=O)(=O)N3CC4CCC(CC4)C3)ccc21 -US08859572B2,2,COc1c(OCCCS(=O)(=O)N2CCOCC2)ccc2c1N=C(N)N1CCN=C21.Nc1ccc(C(=O)O)cn1>>COc1c(OCCCS(=O)(=O)N2CCOCC2)ccc2c1N=C(NC(=O)c1ccc(N)nc1)N1CCN=C21 -US05849779,6,CCOC(=O)c1cn(C(=O)OC(C)(C)C)nc1NC(=O)Nc1ccccc1>>CCOC(=O)c1c[nH]nc1NC(=O)Nc1ccccc1 -US20100216746A1,6,CCOC(=O)c1c(C)nc(C(C)C)n1COCC[Si](C)(C)C>>Cc1nc(C(C)C)n(COCC[Si](C)(C)C)c1C(=O)O -US20080194640A1,1,C=Cn1cc(C=O)cn1.CC(C)c1ccc(N)cn1>>C=Cn1cc(CNc2ccc(C(C)C)nc2)cn1 -US20110269741A1,6,CCOC(=O)c1c[nH]c2cnc(Cc3cccc(Cl)c3)nc2c1=O>>O=C(O)c1c[nH]c2cnc(Cc3cccc(Cl)c3)nc2c1=O -US20050256099A1,2,CS(=O)(=O)N1CCC(C2CCNCC2)CC1.Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc2nc[nH]c12>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(S(C)(=O)=O)CC3)CC2)cc2nc[nH]c12 -US07109186B2,2,CC1(C)OC(=O)C(=CC(=O)Cl)O1.Clc1ccc(CNCCCc2ccccc2)cc1Cl>>CC1(C)OC(=O)C(=CC(=O)N(CCCc2ccccc2)Cc2ccc(Cl)c(Cl)c2)O1 -US06833456B2,1,CI.COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1>>COC(=O)[C@@H]1C[C@@H](OC)CN1C(=O)OCc1ccccc1 -US20050282819A1,7,CC(=O)NC1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)ccc2C1(C)C>>CCNC1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)ccc2C1(C)C -US20130158031A1,2,CNOC.O=C(O)c1ccc(Br)cc1F>>CON(C)C(=O)c1ccc(Br)cc1F -US06448243B1,1,NS(=O)(=O)c1ccc(CCBr)cc1.c1ccc2c(c1)CCN2C1CCNCC1>>NS(=O)(=O)c1ccc(CCN2CCC(N3CCc4ccccc43)CC2)cc1 -US07662831B2,2,CC(=O)OC(C)=O.Nc1cc2c3c(c1)c1c(n3CCC2)CCCC1>>CC(=O)Nc1cc2c3c(c1)c1c(n3CCC2)CCCC1 -US20140051857A1,3,CC(C)[Mg+].COCOc1c(C=O)csc1-c1ccc(C(C)(C)C)cc1>>COCOc1c(C(O)C(C)C)csc1-c1ccc(C(C)(C)C)cc1 -US20140315801A1,7,Cn1c(CN2CCOCC2)cnc1-c1cc2nccc(Oc3ccc([N+](=O)[O-])cc3F)c2s1>>Cn1c(CN2CCOCC2)cnc1-c1cc2nccc(Oc3ccc(N)cc3F)c2s1 -US20050176966A1,2,CC(=O)Nc1cnc(-c2ccccc2)n(CC(=O)O)c1=O.COC(=O)[C@@H](N)C(C)C>>COC(=O)[C@@H](NC(=O)Cn1c(-c2ccccc2)ncc(NC(C)=O)c1=O)C(C)C -US20090035215A1,6,CC(C)(C)[Si](O)(CC(=O)OCc1ccccc1)C(C)(C)C>>CC(C)(C)[Si](O)(CC(=O)O)C(C)(C)C -US08093239B2,1,COc1cc(N2CCC(N3CCN(S(C)(=O)=O)CC3)CC2)ccc1N.O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3c(F)cccn3c2-c2ccnc(Cl)n2)c1>>COc1cc(N2CCC(N3CCN(S(C)(=O)=O)CC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3c(F)cccn23)n1 -US20060025414A1,2,CN=C=S.Clc1cccc(-n2nnc(C3COCCN3)n2)c1>>CNC(=S)N1CCOCC1c1nnn(-c2cccc(Cl)c2)n1 -US04371468,7,COC(=O)c1nc(C)n2c1CN=C(c1ccccc1F)c1cc(Cl)ccc1-2>>Cc1nc(CO)c2n1-c1ccc(Cl)cc1C(c1ccccc1F)=NC2 -US20110237573A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(Br)cn1>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1 -US04596870,1,O=CN(CCl)c1ccccc1.O=c1ncc(Cl)c[nH]1>>O=CN(Cn1cc(Cl)cnc1=O)c1ccccc1 -US20140114068A1,7,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NC(=O)c1ccc(N)o1>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NC(=O)c1ccc(N)o1 -US20130005721A1,4,C#CC(O)(CC)C(F)(F)F.CCOC(=O)c1cc2cc(CN=[N+]=[N-])ccn2c1-c1ccc(OCC)nc1>>CCOC(=O)c1cc2cc(Cn3cc(C(O)(CC)C(F)(F)F)nn3)ccn2c1-c1ccc(OCC)nc1 -US20020173654A1,2,CCCCc1nc2c(N)nc3cccnc3c2n1CCCCN.O=C=NCc1ccccc1>>CCCCc1nc2c(N)nc3cccnc3c2n1CCCCNC(=O)NCc1ccccc1 -US07595312B2,6,COC(=O)[C@H](CC(=O)N1CCC(N2CCc3ccccc3NC2=O)CC1)Cc1cc(C(F)(F)F)c(N)c(C(F)(F)F)c1>>Nc1c(C(F)(F)F)cc(C[C@@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc1C(F)(F)F -US20080153850A1,6,COC(=O)c1ccccc1-c1ccc(Cl)c(C(=O)NCCC23CC4CC(CC(C4)C2)C3)c1>>O=C(NCCC12CC3CC(CC(C3)C1)C2)c1cc(-c2ccccc2C(=O)O)ccc1Cl -US07495007B2,1,CCI.Cc1ccccc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)ccc12>>CCN1C(=O)CC(c2cccc(Cl)c2)C2(C(=O)N(C(=O)OC(C)(C)C)c3cc(Cl)ccc32)C1c1ccccc1C -US20140243310A1,1,CC(=O)N[C@@H](C)COc1ccc2nc(-c3ccc(O)c(F)c3)oc2c1.CI>>COc1ccc(-c2nc3ccc(OC[C@H](C)NC(C)=O)cc3o2)cc1F -US20090099181A1,3,C#Cc1cccc(NC(=O)c2occc2C)c1.O=C(O)c1cncc(Br)c1>>Cc1ccoc1C(=O)Nc1cccc(C#Cc2cncc(C(=O)O)c2)c1 -US04087530,9,COc1ccc(C2CN(C)CCC2=O)cc1.NO>>COc1ccc(C2CN(C)CCC2=NO)cc1 -US08513239B2,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C1CNCCN1>>CC(C)(C)OC(=O)N1CCC(N2CCNC(=O)C2)CC1 -US20120115813A1,1,CCI.O=Cc1ccc(F)c(O)c1O>>CCOc1c(F)ccc(C=O)c1O -US04727081,2,CN=C=S.NNC(=S)NCCCOc1cccc(CN2CCCCC2)c1>>CNC(=S)NNC(=S)NCCCOc1cccc(CN2CCCCC2)c1 -US04130716,8,O=C1NC(c2ccccc2)c2cc(Cl)ccc2-n2nc(CO)cc21>>O=Cc1cc2n(n1)-c1ccc(Cl)cc1C(c1ccccc1)NC2=O -US20150210739A1,6,CC(C)(C)OC(=O)N1Cc2ccccc2C1C(=O)Nc1c(F)cccc1F>>O=C(Nc1c(F)cccc1F)C1NCc2ccccc21 -US20090062307A1,3,CCn1c(-c2nc(Br)cnc2N)nc2cnccc21.CS(=O)(=O)c1cccc(B(O)O)c1>>CCn1c(-c2nc(-c3cccc(S(C)(=O)=O)c3)cnc2N)nc2cnccc21 -US07687491B2,6,CCc1cc(CN2CC(C(=O)OC)C2)sc1-c1noc(-c2ccc(Oc3cccc(F)c3)c(F)c2)n1>>CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3cccc(F)c3)c(F)c2)n1 -US08450328B2,3,N#Cc1cccc(B(O)O)c1.Nc1nc(Cl)c2nnn(Cc3cccc(C4(O)CCC4)n3)c2n1>>N#Cc1cccc(-c2nc(N)nc3c2nnn3Cc2cccc(C3(O)CCC3)n2)c1 -US20060089371A1,3,COC(=O)[C@H](Cc1ccccc1)Nc1cc(-c2ccc(OS(=O)(=O)C(F)(F)F)cc2)ncn1.COc1ccc(B(O)O)cc1>>COC(=O)[C@H](Cc1ccccc1)Nc1cc(-c2ccc(-c3ccc(OC)cc3)cc2)ncn1 -US07169777B2,6,CCOC(=O)C(c1ccccc1C)N1CCN(C(=O)OC(C)(C)C)CC1>>Cc1ccccc1C(C(=O)O)N1CCN(C(=O)OC(C)(C)C)CC1 -US04549019,8,CC(=O)OO.COC(=O)Nc1cc(OS(=O)(=O)c2ccc(C)cc2)nc(N)n1>>COC(=O)Nc1cc(OS(=O)(=O)c2ccc(C)cc2)nc(N)[n+]1[O-] -US05596012,1,CCc1c(OC)cc(OC)c2c1C(=O)N(CCl)S2(=O)=O.Sc1nnnn1-c1ccccc1>>CCc1c(OC)cc(OC)c2c1C(=O)N(CSc1nnnn1-c1ccccc1)S2(=O)=O -US08461328B2,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CC#N)CC1>>N#CC[C@@H]1CC[C@@H](N)CC1 -US20140288066A1,3,CC1c2c(N3CCOC[C@@H]3C)nc(Cl)nc2C(C)(C)S1(=O)=O.CCNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CCNC(=O)Nc1ccc(-c2nc(N3CCOC[C@@H]3C)c3c(n2)C(C)(C)S(=O)(=O)C3C)cc1 -US07361659B2,2,CC(=O)Nc1ncc(S(=O)(=O)Cl)s1.CC(C)(N)CO>>CC(=O)Nc1ncc(S(=O)(=O)NC(C)(C)CO)s1 -US20110144091A1,2,NC1(C(=O)N[C@@H]2CCc3ccccc3-n3ccnc32)CC1.O=C(O)c1ccc(Cl)cc1>>O=C(NC1(C(=O)N[C@@H]2CCc3ccccc3-n3ccnc32)CC1)c1ccc(Cl)cc1 -US04643990,2,CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)O.C[C@@H](O)[C@H](N)C(=O)N[C@H](C(=O)O)[C@@H](C)O>>CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)N[C@H](C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O -US08877747B2,3,COc1ccc(B(O)O)cc1F.CS(=O)(=O)N1CCC(CCOc2ccc3c(c2)C(=O)C(Br)=C3c2cc(F)cc(F)c2)CC1>>COc1ccc(C2=C(c3cc(F)cc(F)c3)c3ccc(OCCC4CCN(S(C)(=O)=O)CC4)cc3C2=O)cc1F -US08288419B2,2,CC(F)(F)CCCCn1cc(N)cn1.COc1cccc(-c2ocnc2C(=O)O)c1>>COc1cccc(-c2ocnc2C(=O)Nc2cnn(CCCCC(C)(F)F)c2)c1 -US20080045596A1,6,CCCCC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc([C@H]2CCC(=O)[C@@H]2CCCCCCC(=O)O)cc1>>CCCCC[C@H](O)c1ccc([C@H]2CCC(=O)[C@@H]2CCCCCCC(=O)O)cc1 -US05300506,4,CC(C)(C)[Si](C)(C)OCCCC#C[Si](C)(C)C.CCOC(=O)c1ccc(N)c(I)c1>>CCOC(=O)c1ccc2[nH]c([Si](C)(C)C)c(CCCO[Si](C)(C)C(C)(C)C)c2c1 -US20060009443A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CC1NCCNC1=O>>CCOC(=O)CC1C(=O)NCCN1C(=O)OC(C)(C)C -US20140235641A1,9,NO.O=CC1=CCCOC1>>ON=CC1=CCCOC1 -US06828317B2,2,C[Si](C)(C)N=C=O.NC[C@H]1CN(c2ccc(C3=NNC(=O)CS3)c(F)c2)C(=O)O1>>NC(=O)NC[C@H]1CN(c2ccc(C3=NNC(=O)CS3)c(F)c2)C(=O)O1 -US20060148858A1,3,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1/C=C/C(=O)OCC -US20110301161A1,8,Cn1ncnc1-c1ccc(F)cc1CO>>Cn1ncnc1-c1ccc(F)cc1C=O -US20050143422A1,2,COC(=O)[C@@H](NS(=O)(=O)c1ccc(-c2ccc(N)cc2)cc1)C(C)C.Cc1c(C(=O)O)oc2cccc(-c3ccoc3)c12>>COC(=O)[C@@H](NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3oc4cccc(-c5ccoc5)c4c3C)cc2)cc1)C(C)C -US20090233930A9,3,C#Cc1ccccc1.Ic1ccc2c(c1)CCCC2>>C(#Cc1ccc2c(c1)CCCC2)c1ccccc1 -US20080221132A1,6,COc1cc2nc[nH]c(=O)c2cc1OC>>COc1cc2nc[nH]c(=O)c2cc1O -US20030065176A1,3,C=C[Sn](CCCC)(CCCC)CCCC.N#Cc1cccc(Br)c1>>C=Cc1cccc(C#N)c1 -US20130345245A1,6,Cn1c2c(c(-c3cccc(OC(=O)c4cccs4)c3)c1-c1ccnc(N)n1)C(=O)N(C(=O)OC(C)(C)C)CC2>>Cn1c2c(c(-c3cccc(OC(=O)c4cccs4)c3)c1-c1ccnc(N)n1)C(=O)NCC2 -US20120277237A1,4,CNc1ccc(F)cc1N.O=C(O)CCl>>Cn1c(CCl)nc2cc(F)ccc21 -US04992447,1,CCCc1nccn1C(C)CO.CCOC(=O)CC(=O)CCl>>CCCc1nccn1C(C)COCC(=O)CC(=O)OCC -US20130005707A1,7,O=Cc1cccc2nc(Br)nn12>>OCc1cccc2nc(Br)nn12 -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Cc1c(C)cc(C)cc1C)C1CCCCC1>>Cc1cc(C)c(CC(=O)Nc2cc3ccccc3cc2C(=O)N[C@H](C(=O)O)C2CCCCC2)c(C)c1 -US04178460,1,Cc1ccc(O)cc1.FC(F)=C(F)F>>Cc1ccc(OC(F)(F)C(F)F)cc1 -US08283354B2,2,COc1cccc(Cl)c1C(=O)Cl.NC(=O)c1ccccc1N>>COc1cccc(Cl)c1C(=O)Nc1ccccc1C(N)=O -US05025036,1,COC(=O)c1ccc(O)cc1.COc1cccc(CCCCCCBr)c1OC>>COC(=O)c1ccc(OCCCCCCc2cccc(OC)c2OC)cc1 -US07745589B1,1,CC(C)=CCCC(C)=CCCC(C)=CCBr.COC(=O)[C@@H](N)CS>>COC(=O)C(N)CSCC=C(C)CCC=C(C)CCC=C(C)C -US20110152318A1,1,CC(NC(=O)c1coc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1.Oc1cccc(C2CC2)c1>>CC(NC(=O)c1coc(Oc2cccc(C3CC3)c2)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1 -US08471005B2,1,CN1CCN(C)C(c2cccc(N)c2)C1=O.COc1ccc(-c2ccc3cnc(O)nn23)cn1>>COc1ccc(-c2ccc3cnc(Nc4cccc(C5C(=O)N(C)CCN5C)c4)nn23)cn1 -US20110144105A1,7,CN(C)c1ccc(C(=CC2CCCC2)c2cc3cccnc3[nH]2)cc1>>CN(C)c1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1 -US20060142337A1,6,C[C@H](O[C@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@H](O[C@H]1CCNC[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US07268128B2,1,COc1cc(O)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1.OCCBr>>COc1cc(OCCO)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1 -US20090227570A1,9,NO.O=C1CC2CCCC(C1)N2C1CC1>>ON=C1CC2CCCC(C1)N2C1CC1 -US20150225381A1,6,CC(C)(C)OC(=O)NC1(COc2ccc(N3C(=S)N(c4ccc(C#N)c(C(F)(F)F)c4)C(=O)C3(C)C)cn2)CC1>>CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(OCC2(N)CC2)nc1 -US20120115869A1,1,CCC(=O)Nc1cccc(C#N)c1.Fc1cccc(CBr)c1>>CCC(=O)N(Cc1cccc(F)c1)c1cccc(C#N)c1 -US08697725B2,2,CC(=O)OC(C)=O.CC(C)OC(=O)N[C@@H]1C[C@H](C)Nc2ccc(-c3cn(CC(=O)OC(C)(C)C)cn3)cc21>>CC(=O)N1c2ccc(-c3cn(CC(=O)OC(C)(C)C)cn3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C -US20140249131A1,2,C/C=C/C(=O)Cl.COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2ccc(=O)n(-c3cccc(N)c3)c2n1>>C/C=C/C(=O)Nc1cccc(-n2c(=O)ccc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 -US06133485,3,C[C@@H](OC1CCCCO1)C(=O)c1ccc(F)cc1F.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(c1ccc(F)cc1F)[C@@H](C)OC1CCCCO1 -US06982348B2,1,CI.O=C1NC(Cc2ccc(C(F)(F)F)cc2)C(c2ccc(F)cc2)O1>>CN1C(=O)OC(c2ccc(F)cc2)C1Cc1ccc(C(F)(F)F)cc1 -US05428053,2,C[C@H](NC(=O)OCc1ccccc1)C(=O)O.Nn1cccc1>>C[C@H](NC(=O)OCc1ccccc1)C(=O)Nn1cccc1 -US04318912,7,CC(=O)OCCC1CC(=O)N1[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)N1C(=O)CC1CCO -US20150225422A1,6,CC(C)(C)OC(=O)NC(=N)NC(=O)c1cc(-c2ccnc(Nc3ccncn3)c2)cnc1N>>N=C(N)NC(=O)c1cc(-c2ccnc(Nc3ccncn3)c2)cnc1N -US04782176,1,CCCc1c(O)ccc(C(C)=O)c1O.CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1OCCCOCCCBr>>CCCc1c(OCCCOCCCOc2c(C(C)=O)ccc(OCC(=O)OCC)c2CCC)ccc(C(C)=O)c1O -US20090023763A1,3,C#Cc1ccccc1.Nc1nc(-c2ccco2)c(-c2ccncn2)cc1Br>>Nc1nc(-c2ccco2)c(-c2ccncn2)cc1C#Cc1ccccc1 -US08063099B2,2,Cc1nn(C)cc1C(=O)O.NC[C@@H]1[C@H]2C[C@H]2CN1C(=O)c1nc(N)sc1-c1cccc(F)c1>>Cc1nn(C)cc1C(=O)NC[C@@H]1[C@H]2C[C@H]2CN1C(=O)c1nc(N)sc1-c1cccc(F)c1 -US20040138223A1,2,CC(C)c1ccc(NCc2ccc(N(C)C)cc2)cc1.O=C(O)C1CCOc2ccc(F)cc21>>CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCOc3ccc(F)cc32)cc1 -US05071636,1,BrCc1ccccc1.CC(C)(S)[C@@H](N)C(=O)O>>CC(C)(SCc1ccccc1)[C@@H](N)C(=O)O -US05576324,7,CNCC(=O)NCC1Cc2cc(C)c3[nH]c(=O)ccc3c2O1>>CNCC(=O)NCC1Cc2cc(C)c3c(c2O1)CCC(=O)N3 -US20150218186A1,6,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1ncc2cncc(-c3c[nH]c4cnccc34)c2n1>>N[C@@H]1CCCC[C@@H]1Nc1ncc2cncc(-c3c[nH]c4cnccc34)c2n1 -US20150152093A1,1,C[C@H](NC(=O)OC(C)(C)C)c1ccc(C=O)c(F)c1.FC1(F)CCNCC1>>C[C@H](NC(=O)OC(C)(C)C)c1ccc(CN2CCC(F)(F)CC2)c(F)c1 -US20020193402A1,1,C=CCBr.CC(C)(C)OC(=O)[C@@H]1C[C@]2(c3ccccc3)N[C@H]1CC[C@H]2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C=CCN1[C@H]2CC[C@@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@]1(c1ccccc1)C[C@H]2C(=O)OC(C)(C)C -US20070032485A1,2,CCOC(=O)Cl.CC[C@H]1C[C@@H](NC(=O)O[C@@H](C)c2ccccc2)c2nc(OC)ccc2N1>>CCOC(=O)N1c2ccc(OC)nc2[C@H](NC(=O)O[C@@H](C)c2ccccc2)C[C@@H]1CC -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc[nH]n3)cc2c1.OB(O)c1ccncc1>>COc1ccc2c(-c3ccncc3)nc(Nc3cc[nH]n3)cc2c1 -US20030087874A1,1,COc1ccc(Cn2c(=O)ccn([C@@H]3O[C@H]([C@H](O)[C@H](N)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1.O=CCCNC(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1>>COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@H](CC(=O)OCc4ccccc4)NC(=O)OCc4ccccc4)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1 -US20090048343A1,6,COC(C(=O)O)c1ccc(NC(C)=O)cc1>>COC(C(=O)O)c1ccc(N)cc1 -US20090099248A1,6,CCOC(=O)c1cc2c([nH]1)C(Cc1ccccc1)CC2>>O=C(O)c1cc2c([nH]1)C(Cc1ccccc1)CC2 -US08133901B2,2,Brc1cnc(N[C@@H]2CCCNC2)nc1.Cc1nc(C(=O)O)c(-c2ccc(C)c(C)c2)s1>>Cc1nc(C(=O)N2CCC[C@@H](Nc3ncc(Br)cn3)C2)c(-c2ccc(C)c(C)c2)s1 -US05597824,2,Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@H]1CO.O=C(Cl)c1ccccc1>>O=C(Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@H]1CO)c1ccccc1 -US20130005705A1,3,O=C1c2cccc(Br)c2CN1CCc1ccc2ccccc2n1.OB(O)c1cccnc1>>O=C1c2cccc(-c3cccnc3)c2CN1CCc1ccc2ccccc2n1 -US20150141400A1,2,CC(C)(C)OC(=O)NCC(=O)O.CN[C@@H]1CCN(Cc2ccccc2)C1>>CN(C(=O)CNC(=O)OC(C)(C)C)[C@@H]1CCN(Cc2ccccc2)C1 -US20130225614A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=[N+]([O-])c1c[nH]cn1>>O=[N+]([O-])c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US05461050,2,CS(=O)(=O)Cl.Cn1cccc1CCO>>Cn1cccc1CCOS(C)(=O)=O -US20090069305A1,3,CN1CCN(c2ccnc(-c3cccc(OS(=O)(=O)C(F)(F)F)c3)c2)CC1.OB(O)c1ccc(F)cc1>>CN1CCN(c2ccnc(-c3cccc(-c4ccc(F)cc4)c3)c2)CC1 -US09138013B2,2,NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCC[NH2+]3)c21.O=C(O)Cc1ccncn1>>NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCCN3C(=O)Cc3ccncn3)c21 -US20130005707A1,1,C1COCCN1.O=[N+]([O-])c1ccc(Br)nc1>>O=[N+]([O-])c1ccc(N2CCOCC2)nc1 -US05441950,6,CC(C)(CNC(=O)OCc1ccccc1)NC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21>>CC(C)(CN)NC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 -US08288419B2,2,CC(F)(F)CCCCn1ccc(N)n1.O=C(O)/C=C/c1ccccc1Cl>>CC(F)(F)CCCCn1ccc(NC(=O)/C=C/c2ccccc2Cl)n1 -US07098212B2,1,COC(=O)CBr.Cc1ccc(CCC(=O)N2C[C@H](C)N(Cc3ccc(F)cc3)C[C@H]2C)c(O)c1>>COC(=O)COc1cc(C)ccc1CCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C -US20100016293A1,1,CN1CCNCC1.Clc1ccc2nc(Cl)cnc2c1>>CN1CCN(c2cnc3cc(Cl)ccc3n2)CC1 -US20050165058A1,1,COC(=O)c1ccc(Br)c(O)c1.OCCc1ccc(Cl)cc1Cl>>COC(=O)c1ccc(Br)c(OCCc2ccc(Cl)cc2Cl)c1 -US20090143592A1,7,Cc1ccc([N+](=O)[O-])cc1S(C)(=O)=O>>Cc1ccc(N)cc1S(C)(=O)=O -US05817599,1,CCCCCCCCCCCCCCCCCCBr.O=C1CCC(=O)N1>>CCCCCCCCCCCCCCCCCCN1C(=O)CCC1=O -US04481142,7,Clc1ccc2c(c1)C(c1ccccc1Cl)=NCc1cncnc1-2>>Clc1ccc2c(c1)C(c1ccccc1Cl)NCc1cncnc1-2 -US06498165B1,1,CI.C[C@H](Nc1nccc(-n2cnc3cc(N4CCNC4=O)ccc32)n1)c1ccccc1>>C[C@H](Nc1nccc(-n2cnc3cc(N4CCN(C)C4=O)ccc32)n1)c1ccccc1 -US20090233930A9,2,COc1cc(O)cc(-c2cccc(C3(c4ccncc4)NC(=S)N(C)C3=O)c2)c1.CS(=O)(=O)Cl>>COc1cc(OS(C)(=O)=O)cc(-c2cccc(C3(c4ccncc4)NC(=S)N(C)C3=O)c2)c1 -US20090012263A1,2,Nc1ccc2ccn(Cc3c(Cl)cccc3Cl)c2c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc2ccn(Cc3c(Cl)cccc3Cl)c2c1)Oc1ccccc1 -US20140323464A1,2,COc1cc(Nc2nc(NCC3CCNCC3)n3ccnc3c2C(N)=O)cc(OC)c1.N#CCC(=O)O>>COc1cc(Nc2nc(NCC3CCN(C(=O)CC#N)CC3)n3ccnc3c2C(N)=O)cc(OC)c1 -US20060173034A1,1,CCc1ccccc1Nc1c(C(N)=O)cnc2cc(O)c(OC)cc12.OCCN1CCNCC1>>CCc1ccccc1Nc1c(C(N)=O)cnc2cc(OCCN3CCNCC3)c(OC)cc12 -US06423689B1,2,CC(C)(C)N.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)C(=O)O>>CC(C)(C)NC(=O)[C@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)OC(C)(C)C -US20080161295A1,1,BrCC[C@H]1CO1.O=S1(=O)NCc2ccccc2N1c1ccccc1F>>O=S1(=O)N(CC[C@H]2CO2)Cc2ccccc2N1c1ccccc1F -US20050209324A1,7,O=[N+]([O-])c1c(Cl)ccc2[nH]ncc12>>Nc1c(Cl)ccc2[nH]ncc12 -US20040116460A1,1,Cc1onc2c1c(=O)n(C1CC(COS(C)(=O)=O)CN(C(=O)OC(C)(C)C)C1)c1cccc(Cl)c21.[N-]=[N+]=[N-]>>Cc1onc2c1c(=O)n(C1CC(CN=[N+]=[N-])CN(C(=O)OC(C)(C)C)C1)c1cccc(Cl)c21 -US04086219,2,COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.COc1ccc(COC(=O)N[C@@H](COCc2ccccc2)C(=O)O)cc1>>COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](COCc1ccccc1)NC(=O)OCc1ccc(OC)cc1 -US20090005412A1,1,Cc1cccc(N)c1.O=Cc1cc(F)c(F)cc1F>>Cc1cccc(NCc2cc(F)c(F)cc2F)c1 -US05578605,1,ClCCCBr.O=c1[nH]c2ccccc2o1>>O=c1oc2ccccc2n1CCCCl -US20050197339A1,1,N#Cc1cc([N+](=O)[O-])ccc1F.OCc1cccc(F)c1>>N#Cc1cc([N+](=O)[O-])ccc1OCc1cccc(F)c1 -US04767790,1,CC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC1.[NH4+]>>CC(N)C1(c2ccc(Cl)c(Cl)c2)CCC1 -US20070244131A1,3,COc1nc(Cl)cc(NCCc2ccc(C(F)(F)F)cc2F)n1.N#CCc1cccc(B(O)O)c1>>COc1nc(NCCc2ccc(C(F)(F)F)cc2F)cc(-c2cccc(CC#N)c2)n1 -US20010044547A1,6,CC(C)[C@H](N)C(=O)N(C)C(=O)OCc1ccccc1>>CNC(=O)[C@@H](N)C(C)C -US20120225854A1,6,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2CN2C3COCC2C(OCc2ccccc2)C3)cc1)C(F)(F)F>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2CN2C3COCC2C(O)C3)cc1)C(F)(F)F -US20140303164A1,2,CSc1ncc(-c2cccc3c(N)nn(C)c23)c([C@@H](N)Cc2cc(F)cc(F)c2)n1.O=C(O)Cn1nc(C(F)F)c2c1C(F)(F)CCC2(F)F>>CSc1ncc(-c2cccc3c(N)nn(C)c23)c([C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)F)c3c2C(F)(F)CCC3(F)F)n1 -US20080146572A1,3,O=C1CCC2(CC1)OCCO2.[Mg+]Cc1ccccc1>>OC1(Cc2ccccc2)CCC2(CC1)OCCO2 -US07381714B2,6,CCOC(=O)c1cn(-c2nc(NC3CCCC3)c3ncn(C4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)nn1>>O=C(O)c1cn(-c2nc(NC3CCCC3)c3ncn(C4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)nn1 -US20070185107A1,2,CC(=O)N1CCN(c2ccc(N)cc2)CC1.COc1cc2c(c(N3CCN(C)CC3)c1)OC(C(=O)O)CC2>>COc1cc2c(c(N3CCN(C)CC3)c1)OC(C(=O)Nc1ccc(N3CCN(C(C)=O)CC3)cc1)CC2 -US20150065468A1,3,CC1(C)OB(c2ccc(CC(=O)Nc3cc(C4(C(F)(F)F)CC4)on3)c(F)c2)OC1(C)C.COc1cc2ncc(Cl)nc2cc1OC>>COc1cc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)nc2cc1OC -US04239901,6,CC(=O)Nc1ccc(CC(=O)O)cc1Br>>Nc1ccc(CC(=O)O)cc1Br -US20100311966A1,2,CCc1[nH]c(C(=O)O)nc1Cl.COC(=O)c1coc(-c2ccc(N)c(C)c2)n1>>CCc1[nH]c(C(=O)Nc2ccc(-c3nc(C(=O)OC)co3)cc2C)nc1Cl -US04341769,2,CCOc1ccc(N)cn1.N#C[S-]>>CCOc1ccc(NC(N)=S)cn1 -US07064116B2,8,CC(O)C#C[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)CC[C@]4(C)[C@H]3CC[C@]12C>>CC(=O)C#C[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)CC[C@]4(C)[C@H]3CC[C@]12C -US20110319392A1,1,CC(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(Cl)n2)s1.Nc1ccc(N2CCN(CCF)CC2)c(F)c1>>CC(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(Nc3ccc(N4CCN(CCF)CC4)c(F)c3)n2)s1 -US20080161313A1,1,OCCBr.Oc1ccc(Br)cc1>>OCCOc1ccc(Br)cc1 -US20090093484A1,3,C#CCn1cccn1.COC(=O)COc1ccc(OC/C=C(/c2ccc(Cl)cc2)c2ccc(I)cc2)cc1C>>COC(=O)COc1ccc(OC/C=C(/c2ccc(Cl)cc2)c2ccc(C#CCn3cccn3)cc2)cc1C -US06646150B1,6,CC(C)[C@H](NC(=O)OCc1ccccc1)[C@H](O)C(F)(F)F>>CC(C)[C@H](N)[C@H](O)C(F)(F)F -US05885999,6,CC(C)(C)OC(=O)N1CCC(c2ccccc2NS(C)(=O)=O)CC1>>CS(=O)(=O)Nc1ccccc1C1CCNCC1 -US04729847,6,CCCCCCC(C)Oc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1>>CCCCCCC(C)Oc1ccc(OC(=O)c2ccc(O)cc2)cc1 -US20120220563A1,3,COC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1.Fc1cc(C(F)(F)F)ccc1Br>>COC(=O)c1cncc(-c2ccc(C(F)(F)F)cc2F)c1 -US20040006236A1,7,N#Cc1cccc2[nH]ccc12>>NCc1cccc2[nH]ccc12 -US20140343030A1,3,CCc1n[nH]cc1Br.C[C@H](NC(=O)c1cnc(N2CC(CC#N)(n3cc(B4OC(C)(C)C(C)(C)O4)cn3)C2)cn1)C(F)(F)F>>CCc1n[nH]cc1-c1cnn(C2(CC#N)CN(c3cnc(C(=O)N[C@@H](C)C(F)(F)F)cn3)C2)c1 -US04937240,2,C1CCNCC1.Cc1nnc2n1-c1sc(CC(=O)O)cc1C(c1ccccc1Cl)=NC2C>>Cc1nnc2n1-c1sc(CC(=O)N3CCCCC3)cc1C(c1ccccc1Cl)=NC2C -US08598357B2,2,CCCC(=O)O.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1>>CCCC(=O)N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1 -US20100305093A1,9,COC(=O)c1cc(OC)c(S(C)(=O)=O)cc1Br>>COC(=O)c1ccc(S(C)(=O)=O)c(OC)c1 -US06476278B1,7,CC(C)(C)C1CCC(=O)CC1>>CC(C)(C)[C@@H]1CC[C@@H](O)CC1 -US06476278B1,7,CC(C)(C)C1CCC(=O)CC1>>CC(C)(C)[C@@H]1CC[C@H](O)CC1 -US07425568B2,7,O=C1CC(c2ccccc2)Oc2cc(O)ccc21>>Oc1ccc2c(c1)OC(c1ccccc1)CC2 -US20140057937A1,2,Fc1ccc(-n2ncc3c2CCCN3)cc1.O=C(O)Cc1ccc(Cl)c(OC(F)(F)F)c1>>O=C(Cc1ccc(Cl)c(OC(F)(F)F)c1)N1CCCc2c1cnn2-c1ccc(F)cc1 -US08344161B2,3,C#CC(=O)OCC.Fc1cc(I)ccc1Cl>>CCOC(=O)C#Cc1ccc(Cl)c(F)c1 -US20140148437A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(C2CC2)c2[nH]ccc2c1>>CC(C)(C)OC(=O)Nc1cc(C2CC2)c2[nH]ccc2c1 -US05646300,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nn1ccc2ccccc21>>CC(C)(C)OC(=O)Nn1ccc2ccccc21 -US04520102,8,C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C>>C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C -US07786142B2,1,ClC[C@H]1CO1.Oc1cccc2[nH]c3ccccc3c12>>c1ccc2c(c1)[nH]c1cccc(OC[C@@H]3CO3)c12 -US20080262086A1,1,CCCC=O.CCCCOC(=O)c1cc(N)c(Oc2ccccc2)c(S(N)(=O)=O)c1>>CCCCNc1cc(C(=O)OCCCC)cc(S(N)(=O)=O)c1Oc1ccccc1 -US20140121200A1,6,CN(CCO)c1ccc(-c2cc3nccnc3c(NCC3CN(C(=O)OC(C)(C)C)CCC3(F)F)n2)cc1>>CN(CCO)c1ccc(-c2cc3nccnc3c(NCC3CNCCC3(F)F)n2)cc1 -US20090076147A1,2,C=C[C@H](OCc1ccccc1)C(C)(C)CO.O=C1c2ccccc2C(=O)N1CCCS(=O)(=O)Cl>>C=C[C@H](OCc1ccccc1)C(C)(C)COS(=O)(=O)CCCN1C(=O)c2ccccc2C1=O -US20090163714A1,6,Fc1ccc(-c2c[nH]c(C3CCN(Cc4ccccc4)CC3)n2)cc1>>Fc1ccc(-c2c[nH]c(C3CCNCC3)n2)cc1 -US20070049620A1,1,CS(=O)c1ccc(CCBr)cc1.Fc1ccc(-c2[nH]cc(C3=CCNCC3)c2-c2ccncc2)cc1Cl>>CS(=O)c1ccc(CCN2CC=C(c3c[nH]c(-c4ccc(F)c(Cl)c4)c3-c3ccncc3)CC2)cc1 -US20150225367A1,2,CS(=O)(=O)Cl.NC1CCN(c2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cn2)CC1>>CS(=O)(=O)NC1CCN(c2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cn2)CC1 -US20150210688A1,6,COCc1nc(Cl)c(-c2cc(C(=O)OC)ccc2C)[nH]1>>COCc1nc(Cl)c(-c2cc(C(=O)O)ccc2C)[nH]1 -US04957911,6,CC(=O)N1CCCC(=O)c2c(Cl)cccc2CCC1=O>>O=C1CCc2cccc(Cl)c2C(=O)CCCN1 -US20080242859A1,1,CCCC[Sn](CI)(CCCC)CCCC.CN(CCO)C1CCCCC1>>CCCC[Sn](CCCC)(CCCC)COCCN(C)C1CCCCC1 -US20120157436A1,6,CC(C)(C)OC(=O)NNC(=O)c1cnc(Cl)cn1>>NNC(=O)c1cnc(Cl)cn1 -US20060223801A1,1,COC(=O)c1cc(Cl)nc(Cl)c1.C[S-]>>COC(=O)c1cc(Cl)nc(SC)c1 -US06197798B1,1,Cc1cccc(C(=O)Nc2ccc3c(c2)CC(N)C3)c1-c1ccc(C(F)(F)F)cc1.O=Cc1ncc[nH]1>>Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NCc2ncc[nH]2)C3)c1-c1ccc(C(F)(F)F)cc1 -US06444683B2,1,CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC(C=O)=C(Cl)[C@@]4(C)CC[C@@H]32)C1.c1c[nH]cn1>>CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC(C=O)=C(n5ccnc5)[C@@]4(C)CC[C@@H]32)C1 -US20060183762A1,1,CC(C)(C)OC(=O)NC1CCNC1.CCOC(=O)c1cc(F)c(F)cc1F>>CCOC(=O)c1cc(F)c(N2CCC(NC(=O)OC(C)(C)C)C2)cc1F -US08236950B2,1,Cc1ccc(Sc2ccc(O)cc2)c(N)c1.Cc1ccc2c(Cl)ccnc2n1>>Cc1ccc(Sc2ccc(O)cc2)c(Nc2ccnc3nc(C)ccc23)c1 -US20050261327A1,7,N#CC1CCC2(CC1)OCCO2>>NCC1CCC2(CC1)OCCO2 -US20090281075A1,1,NCc1cccc(Cl)c1Cl.O=[N+]([O-])c1cnc(Br)cc1Br>>O=[N+]([O-])c1cnc(Br)cc1NCc1cccc(Cl)c1Cl -US20030176454A1,8,Brc1cccc2cnccc12.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc2c(Br)cccc2c1 -US20090306133A1,7,CN(C)C(=O)COC1CCN(C(=O)OC(C)(C)C)CC1>>CN(C)CCOC1CCN(C(=O)OC(C)(C)C)CC1 -US20140171404A1,3,C=CC(=O)OC.Clc1cc(Cl)cc(I)c1>>COC(=O)/C=C/c1cc(Cl)cc(Cl)c1 -US20100144694A1,1,CC1(C)NN(C2CCCCCCC2)C1=O.Fc1ccc(Cl)c(CBr)c1>>CC1(C)C(=O)N(C2CCCCCCC2)N1Cc1cc(F)ccc1Cl -US20130030012A1,1,N#Cc1cc(O)cc(F)c1.O=Cc1ccc(F)c(F)c1>>N#Cc1cc(F)cc(Oc2ccc(C=O)cc2F)c1 -US06440941B1,1,O=C1c2ccccc2C(=O)N1CCCCBr.c1cncc(-c2cc[nH]n2)c1>>O=C1c2ccccc2C(=O)N1CCCCn1ccc(-c2cccnc2)n1 -US20130109710A1,6,CC[Si](CC)(CC)OC1C(C(=O)OC)CCC12CCCCC2>>COC(=O)C1CCC2(CCCCC2)C1O -US20020156081A1,1,CN1CCC(=O)CC1.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCNC1>>CN1CCC(N2CCC(n3nc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)C2)CC1 -US20110118230A1,3,C=C[Sn](CCCC)(CCCC)CCCC.Nc1cnc(Cl)c(Br)c1-c1cc(-c2ccc(CN3CCCCC3)cc2)cnc1F>>C=Cc1c(Cl)ncc(N)c1-c1cc(-c2ccc(CN3CCCCC3)cc2)cnc1F -US20150218124A1,3,COc1cc(C#N)c(Br)c(C#N)c1O.Cc1ccc(CB2OC(C)(C)C(C)(C)O2)c(C)c1>>COc1cc(C#N)c(Cc2ccc(C)cc2C)c(C#N)c1O -US20130245006A1,5,O=C(O)c1ccc(C2CCNCC2)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)c1ccc(C2CCN(C(=O)C(F)(F)F)CC2)cc1 -US05750737,6,CCOC(=O)[C@H](O)[C@@H](N)c1ccccc1>>N[C@@H](c1ccccc1)[C@@H](O)C(=O)O -US07067537B2,4,Cc1ccncc1C(=O)CBr.NC(=S)c1cccnc1>>Cc1ccncc1-c1csc(-c2cccnc2)n1 -US05874382,7,O=[N+]([O-])c1cc2c(cc1F)OCS(=O)(=O)N2Cc1ccccc1>>Nc1cc2c(cc1F)OCS(=O)(=O)N2Cc1ccccc1 -US08765744B2,1,CC1(C)COC2(CCC(O)(CC=O)CC2)OC1.Cc1ccc(C)c([C@H](C)N)c1>>Cc1ccc(C)c([C@H](C)NCCC2(O)CCC3(CC2)OCC(C)(C)CO3)c1 -US20050148619A1,1,CN(C)c1cccc2c(S(=O)(=O)NCCCOCCOCCCN)cccc12.O=[N+]([O-])c1c(Cl)nc2ccccc2c1Cl>>CN(C)c1cccc2c(S(=O)(=O)NCCCOCCOCCCNc3c([N+](=O)[O-])c(Cl)nc4ccccc34)cccc12 -US20060270706A1,7,CCOC(=O)Cc1cc(/C=C2\CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCC2=O)nn1C(=O)OC(C)(C)C>>CCOC(=O)Cc1cc(/C=C2\CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCC2O)nn1C(=O)OC(C)(C)C -US20140235623A1,2,CC(C)=Cc1cccc(N)c1C#N.O=C=NC(=O)c1ccccc1>>CC(C)=Cc1cccc(NC(=O)NC(=O)c2ccccc2)c1C#N -US20100298287A1,7,CCC(CC)c1ccc(Cl)c2nc3n(c12)CCCCN3c1ncc([N+](=O)[O-])cc1C>>CCC(CC)c1ccc(Cl)c2nc3n(c12)CCCCN3c1ncc(N)cc1C -US20120270838A1,3,CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COC(=O)c1cccc(C=O)c1>>CC=Cc1cccc(C(=O)OC)c1 -US08299267B2,1,BrCc1ccccc1.COC(=O)c1cc(O)cc(C(=O)OC)c1>>COC(=O)c1cc(OCc2ccccc2)cc(C(=O)OC)c1 -US06458772B1,6,COc1ccc(COC(=O)C2CCC(OC(=O)[C@@H](NC(=O)OCc3ccccc3)C(C)C)CC2)cc1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OC1CCC(C(=O)O)CC1 -US20120283216A1,6,CCOc1ccc2ccc(OC(CC)C(=O)OC)cc2c1>>CCOc1ccc2ccc(OC(CC)C(=O)O)cc2c1 -US05783593,1,CCCN.O=Cc1cccc(Oc2ccccc2)c1>>CCCNCc1cccc(Oc2ccccc2)c1 -US05198434,5,CCc1cc(=O)c2c([nH]1)CCNC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCc1cc(=O)c2c([nH]1)CCN(C(=O)C(F)(F)F)C2 -US08217177B2,9,COc1ncc2c(=O)cc[nH]c2c1Br>>COc1cc2[nH]ccc(=O)c2cn1 -US07279490B2,1,Cc1ccccc1CBr.O=C1CCNCC1>>Cc1ccccc1CN1CCC(=O)CC1 -US20130109661A1,1,CC1(C)CCCN1.Nc1cccc(F)n1>>CC1(C)CCCN1c1cccc(N)n1 -US08293768B2,2,Cc1cc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)O.Cc1cnc(CN)cn1>>Cc1cnc(CNC(=O)c2sc(-n3cnn(Cc4ccc(F)cc4)c3=O)cc2C)cn1 -US07714010B2,1,CCCCCN1C(=O)C(C)(C)c2cc(NC(=O)CCc3ccccc3)c([N+](=O)[O-])cc21.CI>>CCCCCN1C(=O)C(C)(C)c2cc(N(C)C(=O)CCc3ccccc3)c([N+](=O)[O-])cc21 -US20100041658A1,1,C1COCCN1.CCc1ccc(Oc2ccc(NS(=O)(=O)CCCCl)cc2F)c(OC)c1>>CCc1ccc(Oc2ccc(NS(=O)(=O)CCCN3CCOCC3)cc2F)c(OC)c1 -US20100331315A1,3,O=C1CSC(=S)N1.O=Cc1ccc(-c2cc(C(=O)O)ccc2Cl)o1>>O=C1NC(=S)SC1=Cc1ccc(-c2cc(C(=O)O)ccc2Cl)o1 -US06906065B2,2,CN(C)CCCN.N#Cc1cnc(Nc2ccc(S(=O)(=O)F)cc2)nc1N>>CN(C)CCCNS(=O)(=O)c1ccc(Nc2ncc(C#N)c(N)n2)cc1 -US20090023725A1,2,CCN.Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1>>CCNC(=O)c1ccc(C)c(B2OC(C)(C)C(C)(C)O2)c1 -US20120165326A1,6,CC(C)(C)OC(=O)Nc1nc2cc(F)c(Sc3nnc4ccc(-c5ccc(F)cc5)nn34)cc2s1>>Nc1nc2cc(F)c(Sc3nnc4ccc(-c5ccc(F)cc5)nn34)cc2s1 -US20070185103A1,1,CCOC(=O)C1CNc2ccccc2O1.CI>>CCOC(=O)C1CN(C)c2ccccc2O1 -US20150126522A1,2,CC(=O)OC(C)=O.CCC(C)Nc1cc(Br)cc(C(=O)OC)c1C>>CCC(C)N(C(C)=O)c1cc(Br)cc(C(=O)OC)c1C -US05254558,6,CC(C)C(NC(=O)Cn1c(-c2cccs2)ncc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F>>CC(C)C(NC(=O)Cn1c(-c2cccs2)ncc(N)c1=O)C(=O)C(F)(F)F -US09120749B2,3,CC(=O)c1cnc2ccc(Br)cc2c1Nc1cccc(CCN(C)C)c1.CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C>>CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1cccc(CCN(C)C)c1 -US05461060,1,CSCCl.Cc1c(-c2ccccc2)[nH]c(=S)[nH]c1=O>>CSCn1c(-c2ccccc2)c(C)c(=O)[nH]c1=S -USRE045183E1,6,CCOC(=O)CCSc1cnc(NC(=O)N(C2CCC(C)CC2)C2CCN(C(C)=O)CC2)s1>>CC(=O)N1CCC(N(C(=O)Nc2ncc(SCCC(=O)O)s2)[C@@H]2CC[C@@H](C)CC2)CC1 -US20100168418A1,7,CC(C)(C)OC(=O)N1CCC(NC(=O)OCc2ccccc2)(C(=O)O)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(NC(=O)OCc2ccccc2)CC1 -US20070093521A1,2,CCOc1cc(CN2CCC(Nc3nc4cccc(N)c4o3)CC2)cc(OCC)c1F.Cn1cnc(S(=O)(=O)Cl)c1>>CCOc1cc(CN2CCC(Nc3nc4cccc(NS(=O)(=O)c5cn(C)cn5)c4o3)CC2)cc(OCC)c1F -US07351719B2,7,N#CCc1ccc(CN2CCCC2)cc1>>NCCc1ccc(CN2CCCC2)cc1 -US20090137562A1,1,CC(C)N1CCNC(=O)C1.CN(Cc1cc(CCl)ccc1Oc1ccc(Cl)c(Cl)c1)C(=O)OC(C)(C)C>>CC(C)N1CCN(Cc2ccc(Oc3ccc(Cl)c(Cl)c3)c(CN(C)C(=O)OC(C)(C)C)c2)C(=O)C1 -US07902201B2,1,Cc1onc(-c2ccccc2)c1CO.Oc1cnc2ccccc2n1>>Cc1onc(-c2ccccc2)c1COc1cnc2ccccc2n1 -US04042397,2,NC1CCCCC1.O=C=Nc1ccccc1S(=O)(=O)F>>O=C(Nc1ccccc1S(=O)(=O)F)NC1CCCCC1 -US20100029636A1,6,CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCN(C(=O)OCc6ccccc6)CC5)c4)cnn3c2N)cc1>>CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCNCC5)c4)cnn3c2N)cc1 -US04252814,1,N#CCS.O=C(Cl)c1ccco1>>N#CCSC(=O)c1ccco1 -US20120190665A1,6,COc1ccc(Cl)cc1-c1nn(C(C)C(=O)OC(C)(C)C)cc1NC(=O)c1n[nH]c2cncnc12>>COc1ccc(Cl)cc1-c1nn(C(C)C(=O)O)cc1NC(=O)c1n[nH]c2cncnc12 -US20100152192A1,2,Nc1nc(C2CC2)cs1.O=C(O)c1c(/C=C/c2cccc(OC(F)F)c2OCC2CCC2)nc2sccn12>>O=C(Nc1nc(C2CC2)cs1)c1c(/C=C/c2cccc(OC(F)F)c2OCC2CCC2)nc2sccn12 -US20100048502A1,9,Cc1ccc2ccc(O)c(C=O)c2n1.NO>>Cc1ccc2ccc(O)c(C=NO)c2n1 -US08008491B2,1,CCOc1ccc(B(O)O)cc1.O=Cc1c(Cl)[nH]c2ccccc12>>CCOc1ccc(-n2c(Cl)c(C=O)c3ccccc32)cc1 -US20150257385A1,1,COC(=O)c1ccc(Cl)nc1.Oc1ccc(Cl)cc1>>COC(=O)c1ccc(Oc2ccc(Cl)cc2)nc1 -US20090203665A1,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.c1ccc2c(c1)CNC2>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1Cc2ccccc2C1 -US05840917,6,CCc1ccsc1C(=O)OC>>CCc1ccsc1C(=O)O -US20110250135A1,2,CC(=O)Oc1cccc(C(=O)NCC(=O)O)c1.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>CC(=O)Oc1cccc(C(=O)NCC(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)c1 -US20060257987A1,3,COC(=O)C=Cc1ccc(OCc2ccccc2)cc1C.C[S+](C)(C)=O>>COC(=O)C1CC1c1ccc(OCc2ccccc2)cc1C -US06291499B1,7,C(=C1CCC2(CC1)OCCO2)c1ccccc1>>c1ccc(CC2CCC3(CC2)OCCO3)cc1 -US20130040930A1,2,CCOC(=O)c1ccc(N2CCCS2(=O)=O)nc1.c1nc(N2CCNCC2)c(C2CC2)cc1C1CC1>>O=C(c1ccc(N2CCCS2(=O)=O)nc1)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1 -US20150119385A1,6,COC(OC)c1ccc2c(n1)N(C(=O)Nc1cnc(C#N)cn1)CCC2>>N#Cc1cnc(NC(=O)N2CCCc3ccc(C=O)nc32)cn1 -US06949536B2,3,Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(Br)cc1.OB(O)c1ccoc1>>Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(-c2ccoc2)cc1 -US20140378491A1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCC(F)(F)CC1>>CCOC(=O)C=C1CCC(F)(F)CC1 -US20020037888A1,8,Cn1cncc1C(O)c1ccc(C#N)c(F)c1>>Cn1cncc1C(=O)c1ccc(C#N)c(F)c1 -US20090264405A1,1,Nc1ccccc1.O=C(CBr)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1>>O=C(CNc1ccccc1)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1 -US20140162971A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#Cc1ccc(Oc2ccc(N)cc2Br)cc1>>CC1(C)OB(c2cc(N)ccc2Oc2ccc(C#N)cc2)OC1(C)C -US20070287725A1,7,O=[N+]([O-])c1cnc2ccccc2c1NCc1cc(-c2cccnc2)on1>>Nc1cnc2ccccc2c1NCc1cc(-c2cccnc2)on1 -US20110160256A1,2,COC(=O)c1nc(-c2c(Cl)cnn2C)cs1.N[C@@H](Cc1cccc(F)c1)CN1C(=O)c2ccccc2C1=O>>Cn1ncc(Cl)c1-c1csc(C(=O)N[C@@H](Cc2cccc(F)c2)CN2C(=O)c3ccccc3C2=O)n1 -US20090036492A1,1,CI.O=Cc1cc(O)cc2ccccc12>>COc1cc(C=O)c2ccccc2c1 -US20060264415A1,1,O=C(COCc1ccc(F)cc1)NCCCCC1CCNC1.O=Cc1c[nH]c2ccccc12>>O=C(COCc1ccc(F)cc1)NCCCCC1CCN(Cc2c[nH]c3ccccc23)C1 -US20120252779A1,1,ClCCN1CCCCC1.Cn1cc(Nc2ncc3cnn(Cc4cccc(O)c4)c3n2)cn1>>Cn1cc(Nc2ncc3cnn(Cc4cccc(OCCN5CCCCC5)c4)c3n2)cn1 -US20110166121A1,9,CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(Oc3ccc(C(=O)O)cc3)nc2s1>>CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(Oc3ccc(C=O)cc3)nc2s1 -US07732618B2,2,CCCc1nc2cc(NCc3ccccc3)ccc2n1CC(=O)OC(C)(C)C.O=C(Cl)c1ccc(Cl)cc1>>CCCc1nc2cc(N(Cc3ccccc3)C(=O)c3ccc(Cl)cc3)ccc2n1CC(=O)OC(C)(C)C -US08569535B2,2,CCOC(=O)C1(N)Cc2ccccc2C1.O=C(O)c1ncccc1F>>CCOC(=O)C1(NC(=O)c2ncccc2F)Cc2ccccc2C1 -US04001244,2,CC(C)NCCN(C(C)C)C(C)C.COc1cc2c(cc1OC)C(c1ccccc1)N(C(=O)Cl)CC2>>COc1cc2c(cc1OC)C(c1ccccc1)N(C(=O)N(CCN(C(C)C)C(C)C)C(C)C)CC2 -US07504403B2,1,NCCc1ccccc1Cl.O=c1cc(-c2ccccc2)cc2n1CCCN2c1cc(Cl)ncn1>>O=c1cc(-c2ccccc2)cc2n1CCCN2c1cc(NCCc2ccccc2Cl)ncn1 -US20110009399A1,1,COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)CC[C@@]34OCCc3cc(CCl)ccc34)cc21.COCCO>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)CC[C@@]34OCCc3cc(COCCOC)ccc34)cc21 -US05480892,8,CC1(CO)CCN(CCc2ccccc2)CC1>>CC1(C=O)CCN(CCc2ccccc2)CC1 -US20090099169A1,2,Cc1cc(C(=O)Cl)nn1Cc1cc(Cl)cc2cc(C3CC3)oc12.NN1CCOCC1>>Cc1cc(C(=O)NN2CCOCC2)nn1Cc1cc(Cl)cc2cc(C3CC3)oc12 -US20030149060A1,1,CCn1cnc2c(N)nc(I)nc21.SCc1ccccc1>>CCn1cnc2c(N)nc(SCc3ccccc3)nc21 -US20100094000A1,9,ClCCCCOCc1ccccc1.NN>>NNCCCCOCc1ccccc1 -US06825222B2,6,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccc(-c4c(C)noc4C)cc3)oc2C)cc1>>Cc1noc(C)c1-c1ccc(-c2nc(CCOc3ccc(OC(C)(C)C(=O)O)cc3)c(C)o2)cc1 -US20040006141A1,6,CCCCC(Cc1ccc(OCCNC(=O)c2ccc(O)nc2)cc1)C(=O)OCC>>CCCCC(Cc1ccc(OCCNC(=O)c2ccc(O)nc2)cc1)C(=O)O -US05780465,7,CSc1ncncc1C1c2c(F)cccc2C(=O)C1(C)C>>CSc1ncncc1C1c2c(F)cccc2CC1(C)C -US08410089B2,2,CC(C)OC(=O)N1CCC(Oc2cc(N3CCc4cc(N)ccc43)ncn2)CC1.COCC(=O)Cl>>COCC(=O)Nc1ccc2c(c1)CCN2c1cc(OC2CCN(C(=O)OC(C)C)CC2)ncn1 -US20150051171A1,1,Cc1ccc(-n2ccc(O)n2)cc1.Cn1nnn(-c2cccc(Cl)c2CBr)c1=O>>Cc1ccc(-n2ccc(OCc3c(Cl)cccc3-n3nnn(C)c3=O)n2)cc1 -US07196104B2,6,CCOC(=O)c1csc(-c2ccc(S(N)(=O)=O)cc2)n1>>NS(=O)(=O)c1ccc(-c2nc(C(=O)O)cs2)cc1 -US20080194629A1,1,CC=O.CCN[C@@H]1C[C@H](C(=O)NCC2(CCCCOC)c3ccccc3Oc3ccccc32)CN(C(=O)OC(C)(C)C)C1>>CCN(CC)[C@@H]1C[C@H](C(=O)NCC2(CCCCOC)c3ccccc3Oc3ccccc32)CN(C(=O)OC(C)(C)C)C1 -US05624950,6,COc1ccccc1C1(O)C(O)CCC2CN(Cc3ccccc3)CC21>>COc1ccccc1C1(O)C(O)CCC2CNCC21 -US08222246B2,2,CCCCc1noc(CO)c1COc1ccc(C(=O)O)cn1.O=S1(=O)CCNCC1>>CCCCc1noc(CO)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 -US20120149721A1,2,CCOc1ccc(F)cc1-c1ncnc2c(C(=O)NC3CCNCC3)c(C)[nH]c12.COCC(=O)Cl>>CCOc1ccc(F)cc1-c1ncnc2c(C(=O)NC3CCN(C(=O)COC)CC3)c(C)[nH]c12 -US20050154042A1,6,CCOC(=O)c1c(-c2ccccc2)c(-c2ccc(F)cc2)c(C=O)n1C(C)C>>CC(C)n1c(C=O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)O -US20110053931A1,1,COc1cc2nccc(Cl)c2cc1OC.O=c1c(-c2ccc(O)c(F)c2)cncn1Cc1ccccc1Cl>>COc1cc2nccc(Oc3ccc(-c4cncn(Cc5ccccc5Cl)c4=O)cc3F)c2cc1OC -US20110212956A1,2,CCC1NCCc2ccccc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CCC1c2ccccc2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US20150045378A1,6,COc1ccc(F)c(-c2ncc(CO[Si](C)(C)C(C)(C)C)cc2CC(C)(C)C)c1>>COc1ccc(F)c(-c2ncc(CO)cc2CC(C)(C)C)c1 -US06956037B2,1,CN1CCNCC1.COCCN(C)c1cccc(C(=O)Nc2ccc(C)c(NC(=O)c3cccc(CCl)c3)c2)c1>>COCCN(C)c1cccc(C(=O)Nc2ccc(C)c(NC(=O)c3cccc(CN4CCN(C)CC4)c3)c2)c1 -US05095025,1,C=CCn1c(=N)sc2ccccc21.CC(C)(C)C(=O)Cl>>C=CCn1c(=NC(=O)C(C)(C)C)sc2ccccc21 -US20030004172A1,1,CN(C)S(=O)(=O)c1ccc(CBr)cc1.COc1ccc(CNC(=O)c2cc3c(=O)[nH]c(=O)n(C)c3s2)cc1>>COc1ccc(CNC(=O)c2cc3c(=O)n(Cc4ccc(S(=O)(=O)N(C)C)cc4)c(=O)n(C)c3s2)cc1 -US20140364466A1,2,CCNCc1ccc(C2=NSC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C.CCSCC(=O)O>>CCSCC(=O)N(CC)Cc1ccc(C2=NSC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C -US20090221555A1,2,CC(=O)OC(C)=O.O=[N+]([O-])c1ccc2c(c1)NCCCO2>>CC(=O)N1CCCOc2ccc([N+](=O)[O-])cc21 -US08455521B2,3,CC(C)(C)OC(=O)N1CCCC(C(=O)c2ccccc2)C1.CCCCCC[Mg+]>>CCCCCCC(O)(c1ccccc1)C1CCCN(C(=O)OC(C)(C)C)C1 -US08455477B2,8,CC(C)(C)OC(=O)N1CCC(O)C1>>CC(C)(C)OC(=O)N1CCC(=O)C1 -US04550190,1,BrCCCBr.COC(=O)COc1ccc2ccc(O)c(C(C)=O)c2c1>>COC(=O)COc1ccc2ccc(OCCCBr)c(C(C)=O)c2c1 -US04347187,6,COC(=O)C1CCn2c(C(=O)c3ccc(F)cc3)ccc21>>O=C(c1ccc(F)cc1)c1ccc2n1CCC2C(=O)O -US20090221555A1,1,CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl.Nc1ccc2c(c1)OCCCN2>>CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)OCCCN3)ncc1Cl -US08735417B2,6,Cc1cc(Nc2nccc(O[C@@H]3CCN(C(=O)OC(C)(C)C)C3)n2)cc(-c2cnc(N3CCCNC(=O)C3)s2)c1>>Cc1cc(Nc2nccc(O[C@@H]3CCNC3)n2)cc(-c2cnc(N3CCCNC(=O)C3)s2)c1 -US05994378,3,CC(C)(C)c1csc(-c2cc3cc(C=O)ccc3o2)n1.C[Mg+]>>CC(O)c1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1 -US20080249091A1,1,CCOC(=O)c1[nH]c2ccc(Br)cc2c1Cl.OB(O)c1ccc(OC2CCCC2)cc1>>CCOC(=O)c1c(Cl)c2cc(Br)ccc2n1-c1ccc(OC2CCCC2)cc1 -US05877214,1,C1=COCCC1.OCCOCCOCCOCCO>>OCCOCCOCCOCCOC1CCCCO1 -US20130280245A1,1,COc1ccc(-c2ccc3nnc(-c4cccnc4Cl)n3c2)cc1.C[O-]>>COc1ccc(-c2ccc3nnc(-c4cccnc4OC)n3c2)cc1 -US04594341,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](CSCCNC(=O)OCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](CSCCNC(=O)OCc1ccccc1)C(=O)O -US08106215B2,1,O=C1NC(=O)c2ccccc21.OCC1C2CC(F)(F)CC2CN1Cc1ccccc1>>O=C1c2ccccc2C(=O)N1C[C@@H]1[C@H]2CC(F)(F)C[C@H]2CN1Cc1ccccc1 -US20090082434A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cc(C(F)(F)F)cc(Br)c3O2)cc1.OB(O)c1ccccc1F>>Cc1ccc(S(=O)(=O)OCC2Cc3cc(C(F)(F)F)cc(-c4ccccc4F)c3O2)cc1 -US20010005757A1,6,CC(=O)O[C@H]1CC[C@]2(C)C3=C(C[C@H](O)[C@H]2C1)[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC3>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C[C@H]1[C@H](O)C3 -US20120101039A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cccc(I)c1>>COC(=O)C=Cc1cccc(I)c1 -US20040044057A1,1,O=C1CCCc2c1ccc(O)c2CCl.Sc1cccc2ccccc12>>O=C1CCCc2c1ccc(O)c2CSc1cccc2ccccc12 -US06630461B2,9,BrC(Br)(Br)Br.O=[N+]([O-])c1ccc(CO)cc1>>O=[N+]([O-])c1ccc(CBr)cc1 -US20090137553A1,9,COC(=O)C1CN(c2cc(F)c(N3CCCS(=O)(=O)CC3)c(F)c2)C(=O)O1.N>>NC(=O)C1CN(c2cc(F)c(N3CCCS(=O)(=O)CC3)c(F)c2)C(=O)O1 -US08273769B2,3,C#Cc1cc(C#N)ccc1OCC(=O)OC(C)(C)C.CCCc1ccc(S(C)(=O)=O)cc1I>>CCCc1ccc(S(C)(=O)=O)cc1C#Cc1cc(C#N)ccc1OCC(=O)OC(C)(C)C -US20040198784A1,9,NS(=O)(=O)c1ccc(Br)s1.[C-]#N>>N#Cc1ccc(S(N)(=O)=O)s1 -USRE029467,3,COc1cc(C=O)cc(OC)c1OC.N#CCC(N)=O>>COc1cc(C=C(C#N)C(N)=O)cc(OC)c1OC -US20040077671A1,1,CC(C)(C)OC(=O)N1CCc2[nH]n(-c3cnc4ccccc4n3)c(=O)c2C1.CI>>Cn1c2c(c(=O)n1-c1cnc3ccccc3n1)CN(C(=O)OC(C)(C)C)CC2 -US20150191466A1,7,COc1ccc(COc2ccc(CNc3ccc(I)cc3[N+](=O)[O-])cc2OC)cc1>>COc1ccc(COc2ccc(CNc3ccc(I)cc3N)cc2OC)cc1 -US20090163488A1,2,Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Oc1ccc2nc(N)nn2c1.O=C(O)c1cocn1>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Oc1ccc2nc(NC(=O)c3cocn3)nn2c1 -US20020035092A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.c1c[nH]cn1>>c1ccc(C(c2ccccc2)(c2ccccc2)n2ccnc2)cc1 -US20140371201A1,2,CCOC(=O)/C=C(/C)c1cc(SCc2ccccc2)ccc1Nc1cc(Cl)c(Br)cc1OC>>COc1cc(Br)c(Cl)cc1-n1c(=O)cc(C)c2cc(SCc3ccccc3)ccc21 -US04616086,1,CCCCOC(=O)CCc1ccc(N2CCNCC2)cc1.ClCc1ccc(Cl)cc1>>CCCCOC(=O)CCc1ccc(N2CCN(Cc3ccc(Cl)cc3)CC2)cc1 -US20060041123A1,6,CC(C)(C)OC(=O)N1CCC(CO)(NC(=O)c2ccc3c(n2)NC(=O)CS3)CC1>>O=C1CSc2ccc(C(=O)NC3(CO)CCNCC3)nc2N1 -US20150111885A1,1,CI.O=c1[nH]cc(Br)cc1I>>Cn1cc(Br)cc(I)c1=O -US08853226B2,2,COc1cccc2c1ncc1c(=O)n(-c3cccc(Cl)c3)c(=O)n(C3CCNCC3)c12.O=S(=O)(Cl)c1ccccc1>>COc1cccc2c1ncc1c(=O)n(-c3cccc(Cl)c3)c(=O)n(C3CCN(S(=O)(=O)c4ccccc4)CC3)c12 -US06489321B1,2,Cc1ccccc1C(=O)Cl.Nc1ccc(CN2C(=O)C=C(CCO)Sc3ccccc32)cc1>>Cc1ccccc1C(=O)Nc1ccc(CN2C(=O)C=C(CCO)Sc3ccccc32)cc1 -US20150119362A1,1,Clc1ccc(Cl)c(-c2cc(Cl)c3c(n2)CCC3)c1.Nc1ccc(CCO)cc1>>OCCc1ccc(Nc2cc(-c3cc(Cl)ccc3Cl)nc3c2CCC3)cc1 -US20130053363A1,6,CO[C@]1(CO)CCN(C(=O)OC(C)(C)C)C[C@H]1F>>CO[C@]1(CO)CCNC[C@H]1F -US05668161,3,CSc1ccc(C=O)cc1.O=C(O)Cc1ccc(Cl)cc1>>CSc1ccc(C=C(C(=O)O)c2ccc(Cl)cc2)cc1 -US20050107449A1,3,CCc1nc(-c2ccc(C(F)(F)F)cc2)oc1C=O.C[Mg+]>>CCc1nc(-c2ccc(C(F)(F)F)cc2)oc1C(C)O -US20110262352A1,1,BrCC1COc2ccccc2O1.N#Cc1ccccc1N1CCNCC1>>N#Cc1ccccc1N1CCN(CC2COc3ccccc3O2)CC1 -US20090216021A1,3,CCCCCCc1cccs1.CN(C)C=O>>CCCCCCc1ccc(C=O)s1 -US07429609B2,6,COc1c(C(=O)NCC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)ccc2[nH]nc(/C=C/c3ccc(F)cc3)c12>>COc1c(C(=O)NCC(=O)N2CCNCC2)ccc2[nH]nc(/C=C/c3ccc(F)cc3)c12 -US20090048285A1,6,CCOC(=O)c1cc2c(-c3ccc(C(F)(F)F)cc3)nc(-c3ccc(C(F)(F)F)cc3)cc2n1-c1ccc(OC(C)C)cc1>>CC(C)Oc1ccc(-n2c(C(=O)O)cc3c(-c4ccc(C(F)(F)F)cc4)nc(-c4ccc(C(F)(F)F)cc4)cc32)cc1 -US20090176786A1,2,CN(C(=O)Cl)c1ccc(SC(F)(F)F)cc1F.NCc1ccccn1>>CN(C(=O)NCc1ccccn1)c1ccc(SC(F)(F)F)cc1F -US04524212,6,C[C@H](CC(=O)[C@H](Cc1ccccc1)OC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>C[C@H](CC(=O)[C@H](Cc1ccccc1)OC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)O -US08222257B2,6,CC(C)(C)[Si](OCC#CCCOC1CCCCO1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCC#CCCO)(c1ccccc1)c1ccccc1 -US20150141402A1,1,CC(C)O.Fc1nc(Cl)c2nc[nH]c2n1>>CC(C)n1cnc2c(Cl)nc(F)nc21 -US05525614,1,BrCc1ccccc1.COc1cccc(C=O)c1O>>COc1cccc(C=O)c1OCc1ccccc1 -US04987235,6,COc1cc2c(cc1OC)CN(Cc1ccccc1)C2>>COc1cc2c(cc1OC)CNC2 -US20040176361A1,1,CN1CCNCC1.O=c1[nH]c(Cl)cc2c(Cl)cc(F)cc12>>CN1CCN(c2cc3c(Cl)cc(F)cc3c(=O)[nH]2)CC1 -US06846835B2,1,CC=O.O=C(OC1CCNCC1)[C@](O)(c1ccc(Cl)cc1)[C@@H]1CCC(F)(F)C1>>CCN1CCC(OC(=O)[C@](O)(c2ccc(Cl)cc2)[C@@H]2CCC(F)(F)C2)CC1 -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)C1CCCC1>>Cc1nc(NC(=O)C2CCCC2)sc1C(=O)NCc1ccccc1 -US20060287362A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O[C@@H]1CCCNC1>>CC(C)(C)OC(=O)N1CCC[C@@H](O)C1 -US06069149,1,CN(C)CCCl.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCCN(C)C)cc1 -US20090306197A1,7,CC(C)c1cc2c(c(-c3ccc(F)cc3)c1C(=O)c1ccc(OC(F)(F)F)cc1)C(=O)CC(C)(C)O2>>CC(C)c1cc2c(c(-c3ccc(F)cc3)c1C(=O)c1ccc(OC(F)(F)F)cc1)[C@@H](O)CC(C)(C)O2 -US20120059014A1,7,CCOC(=O)C(C)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(CO)C1CCN(C(=O)OC(C)(C)C)CC1 -US08507510B2,1,C[C@@H](Nc1nc(Cl)ncc1Br)C(C)(C)O.C[Si](C)(C)CCS(=O)(=O)N=S(=O)(CCO)c1ccc(N)cc1>>C[C@@H](Nc1nc(Nc2ccc(S(=O)(CCO)=NS(=O)(=O)CC[Si](C)(C)C)cc2)ncc1Br)C(C)(C)O -US20060252797A1,1,CC(=O)N(c1ccccc1)C1(c2nc(C)cs2)CCNCC1.O=Cc1ccc(OC(F)(F)F)cc1>>CC(=O)N(c1ccccc1)C1(c2nc(C)cs2)CCN(Cc2ccc(OC(F)(F)F)cc2)CC1 -US08569484B2,2,CCOC(=O)c1cn(CCO)c2ncc(Br)cc2c1=O.CS(=O)(=O)Cl>>CCOC(=O)c1cn(CCOS(C)(=O)=O)c2ncc(Br)cc2c1=O -US08962869B2,1,CCCCN(CCCC)CCCCl.Oc1ccccc1>>CCCCN(CCCC)CCCOc1ccccc1 -US20110021493A1,1,CC(C)(C)OC(=O)N1CCc2c(sc3ncc(C#N)c(Cl)c23)C1.Nc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)N1CCc2c(sc3ncc(C#N)c(Nc4ccc(Cl)c(Cl)c4)c23)C1 -US20040023973A1,7,N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2cccc(C=O)c2)c1=O>>N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2cccc(CO)c2)c1=O -US20130216497A1,1,CCC1CC(OCc2ccc(OC)cc2)CC1c1nnc2cnc3[nH]ccc3n12.C[Si](C)(C)CCOCCl>>CCC1CC(OCc2ccc(OC)cc2)CC1c1nnc2cnc3c(ccn3COCC[Si](C)(C)C)n12 -US20120058989A1,7,CCOC(=O)c1cn(C2CC2)c2c(C#CC[C@@H]3CCCN3C(=O)OC(C)(C)C)c(F)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(CCC[C@@H]3CCCN3C(=O)OC(C)(C)C)c(F)c(F)cc2c1=O -US20020040048A1,6,COc1ccc(CS[C@@H]2C[C@@H](C(=O)N(C)NC(=O)OC(C)(C)C)N(S(=O)(=O)c3ccc4ccccc4c3)C2)cc1>>COc1ccc(CS[C@@H]2C[C@@H](C(=O)N(C)N)N(S(=O)(=O)c3ccc4ccccc4c3)C2)cc1 -US20140183422A1,1,Brc1ccccc1I.Cc1cc(C)c(Nc2ccccc2)c(C)c1>>Cc1cc(C)c(N(c2ccccc2)c2ccccc2Br)c(C)c1 -US20100010035A1,7,COCCOCN(c1noc(C)c1C)S(=O)(=O)c1sccc1-c1ccc(C=O)cc1>>COCCOCN(c1noc(C)c1C)S(=O)(=O)c1sccc1-c1ccc(CO)cc1 -US20120028931A1,6,COc1ccc(Cn2nc(C=C3CCN(c4nc(C)ccc4[N+](=O)[O-])CC3)cc2-c2cccs2)cc1>>Cc1ccc([N+](=O)[O-])c(N2CCC(=Cc3cc(-c4cccs4)[nH]n3)CC2)n1 -US07285683B2,6,COc1cc(OC)cc(C(C)(C)CCCCC#C[Si](C)(C)C)c1>>C#CCCCCC(C)(C)c1cc(OC)cc(OC)c1 -US06515011B2,2,CC(C)(C)OC(=O)Cc1ccccc1CN.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)Cc1ccccc1CNC(=O)OCc1ccccc1 -US20110257170A1,1,COC(=O)c1cc(Cl)c2nc(Cl)nc(N3CCOCC3)c2n1.C[S-]>>COC(=O)c1cc(SC)c2nc(Cl)nc(N3CCOCC3)c2n1 -US20100004238A1,1,FC(F)(F)Cn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2cccc3[nH]ccc23)c(Cl)c1>>FC(F)(F)Cn1ccc2ncnc(Nc3ccc(Oc4cccc5[nH]ccc45)c(Cl)c3)c21 -US20150225404A1,1,Cc1ncc(-c2cc(Cl)nc3c2CCCC3)cn1.OCc1ncc(F)cc1F>>Cc1ncc(-c2cc(OCc3ncc(F)cc3F)nc3c2CCCC3)cn1 -US20110251247A1,6,CC(C)(C)OC(=O)NCc1cc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)ccc1Br>>NCc1cc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)ccc1Br -US20150080549A1,1,CC(C)(C)OC(=O)CBr.CN(CC(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21>>CN(CC(=O)OCC(=O)OC(C)(C)C)C(=O)OCC1c2ccccc2-c2ccccc21 -US06060475,5,CC(C)C(=O)c1ccc(Br)cc1.OCCCO>>CC(C)C1(c2ccc(Br)cc2)OCCCO1 -US04634704,1,Fc1ccc(Cn2c(Cl)nc3ccccc32)cc1.Fc1ccc(Cn2c(NC3CCN(C4CCNCC4)CC3)nc3ccccc32)cc1>>Fc1ccc(Cn2c(NC3CCN(C4CCN(c5nc6ccccc6n5Cc5ccc(F)cc5)CC4)CC3)nc3ccccc32)cc1 -US05162318,1,CN(C)CCN.O=[N+]([O-])c1ccccc1Br>>CN(C)CCNc1ccccc1[N+](=O)[O-] -US07589103B2,3,CCN(CC)C(=O)c1ccc2c(c1)Oc1c(Br)cccc1C2=C1CC2CCC(C1)N2.OB(O)c1ccccc1>>CCN(CC)C(=O)c1ccc2c(c1)Oc1c(cccc1-c1ccccc1)C2=C1CC2CCC(C1)N2 -US20070066675A1,3,CC1(C)CC(=O)c2ccc(OS(=O)(=O)C(F)(F)F)cc21.COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc3c(c2)C(C)(C)CC3=O)cc1 -US07683185B2,9,O=C(O)c1cccc(S(=O)(=O)Cl)c1>>O=C(O)c1cccc(S)c1 -US20110046134A1,2,CN(CC(=O)O)C(=O)c1ccc(-c2ccccc2)cc1.O=C(c1ccccc1C(F)(F)F)N1CCNCC1>>CN(CC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)C(=O)c1ccc(-c2ccccc2)cc1 -US08455479B2,4,C#CCN(Cc1ccccc1N=[N+]=[N-])C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1Cc2ccccc2-n2nncc2C1 -US05344845,7,COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1OCC(=O)O>>COc1cc(CCC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1OCC(=O)O -US06310075B1,6,CCOC(=O)N1c2cc3c(cc2[C@H](NC(=O)OCc2ccccc2)C[C@@H]1C)CCC3>>CCOC(=O)N1c2cc3c(cc2[C@H](N)C[C@@H]1C)CCC3 -US20020193367A1,7,CCCN(C)c1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C#N>>CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C#N -US04882338,8,COc1cc2ccnc(CSc3nc4ccccc4[nH]3)c2cc1OC.O=C(OO)c1cccc(Cl)c1>>COc1cc2ccnc(CS(=O)c3nc4ccccc4[nH]3)c2cc1OC -US04888283,1,O=Cc1c(OCCO)cccc1OCCO.[NH4+]>>NCc1c(OCCO)cccc1OCCO -US08673893B2,6,O=C(c1cc(F)cc(F)c1)c1ccc2c(c1)c(NC(=O)C(F)(F)F)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>Nc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(C(=O)c3cc(F)cc(F)c3)cc12 -US07683185B2,1,COC(=O)C=CC=CCBr.Sc1ccc(Cl)cc1>>COC(=O)C=CC=CCSc1ccc(Cl)cc1 -US04311787,3,NC(=O)C1=NN(c2ccccc2)C(=O)C1.O=Cc1ccc(O)cc1>>NC(=O)C1=NN(c2ccccc2)C(=O)C1=Cc1ccc(O)cc1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CCS(=O)(=O)c1ccc(F)c(Br)c1>>CCS(=O)(=O)c1ccc(F)c(C#Cc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)c1 -US08258160B2,4,C#Cc1nc(C)c(C(=O)NCc2ccccc2)s1.[N-]=[N+]=NCc1ccc(C(F)(F)F)cc1>>Cc1nc(-c2cn(Cc3ccc(C(F)(F)F)cc3)nn2)sc1C(=O)NCc1ccccc1 -US04833153,7,O=[N+]([O-])c1ccc(C2=NCCCN2)cc1>>Nc1ccc(C2=NCCCN2)cc1 -US06797823B1,7,O=[N+]([O-])c1ccccc1Oc1ccnc2ccccc12>>Nc1ccccc1Oc1ccnc2ccccc12 -US08227615B2,1,COc1ccccc1C(OS(C)(=O)=O)c1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1.OCCN1CCNCC1>>COc1ccccc1C(c1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1)N1CCN(CCO)CC1 -US20050255575A1,3,C#Cc1ccccc1.CCCCCC/C=C\I>>CCCCCCC=CC#Cc1ccccc1 -US20090118257A1,2,Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2.NCCCn1ccnc1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCCn1ccnc1)O2 -US20100204196A1,2,CC(C)(O)C(=O)O.COc1cc2c(cc1[N+](=O)[O-])NCC2>>COc1cc2c(cc1[N+](=O)[O-])N(C(=O)C(C)(C)O)CC2 -US05173510,8,CCCCCCC/C=C\CCCCCCCC(O)CCCNC(C)=O>>CCCCCCC/C=C\CCCCCCCC(=O)CCCNC(C)=O -US06683090B1,2,N[C@H]1CN2CCC1CC2.O=C(O)/C=C/c1ccoc1>>O=C(/C=C/c1ccoc1)N[C@H]1CN2CCC1CC2 -US08299077B2,1,O=C1NCCc2cc(C3CC3)ccc21.O=Cc1c(Br)cccc1Br>>O=Cc1c(Br)cccc1N1CCc2cc(C3CC3)ccc2C1=O -US08669271B2,3,CC(C)(C)OC(=O)N1CCC(C2Cc3cc(Cl)ncc3O2)CC1.Cn1ccc(B2OC(C)(C)C(C)(C)O2)cc1=O>>Cn1ccc(-c2cc3c(cn2)OC(C2CCN(C(=O)OC(C)(C)C)CC2)C3)cc1=O -US20100022515A1,9,CS(=O)(=O)Oc1ccc2c(c1)CCCCN2S(C)(=O)=O>>CS(=O)(=O)N1CCCCc2cc(O)ccc21 -US05686452,3,CCOC(=O)CP(=O)(OCC)OCC.O=CCC1Cc2ccccc2C1>>CCOC(=O)/C=C/CC1Cc2ccccc2C1 -US07968568B2,1,CC(C)Oc1cc(CN2CCC(N)CC2)cc(OC(C)C)c1.Nc1c(Cl)ncnc1Cl>>CC(C)Oc1cc(CN2CCC(Nc3ncnc(Cl)c3N)CC2)cc(OC(C)C)c1 -US20150038528A1,2,CCOC(=O)C(C)(C)CN.COC(=O)c1nc(C#N)c2cc(Oc3ccc(Cl)cc3)ccc2c1O>>CCOC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(Oc3ccc(Cl)cc3)ccc2c1O -US20080004268A1,2,CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)O)c(-c4ccccc4)c3c2)cc1.NC1CCOCC1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)NC4CCOCC4)c(-c4ccccc4)c3c2)cc1 -US20110178055A1,1,Cc1cc(F)ccc1-c1cc(Cl)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.OC[C@H]1NCC[C@@H]1O>>Cc1cc(F)ccc1-c1cc(N2CC[C@H](O)[C@H]2CO)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090012068A1,1,CS(=O)(=O)OCCOC(c1ccc(C#N)cc1)c1cnc[nH]1>>N#Cc1ccc(C2OCCn3cncc32)cc1 -US20130331419A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(F)cc2c1ccn2Cc1ccc(Cl)cc1>>CC(C)(C)OC(=O)Nc1cc(F)cc2c1ccn2Cc1ccc(Cl)cc1 -US07091350B2,1,O=[N+]([O-])c1c(Br)n[nH]c1Br.OCCBr>>O=[N+]([O-])c1c(Br)nn(CCO)c1Br -US20040063944A1,9,Cn1c(=O)cc(CCc2cccc(Cl)c2)c2cc(C(Cl)(c3ccc(Cl)cc3)c3cccnc3)ccc21.N>>Cn1c(=O)cc(CCc2cccc(Cl)c2)c2cc(C(N)(c3ccc(Cl)cc3)c3cccnc3)ccc21 -US05200111,1,CCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1.C[C@@H](C[C@H](C)Cl)Oc1ccc(O)cc1>>CCCCCCCCOc1ccc(-c2ccc(C(=O)Oc3ccc(O[C@@H](C)C[C@H](C)Cl)cc3)cc2)cc1 -US06251912B1,2,COCCC(C)(N)C#CC(=O)O.Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1>>COCCC(C)(N)C#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 -US20040192720A1,2,CC(=O)Cl.Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)Cc4ccc(C(=O)c5ccc(N)cc5)n4C)c3Cl)c2n1>>CC(=O)Nc1ccc(C(=O)c2ccc(CC(=O)N(C)c3ccc(Cl)c(COc4cccc5ccc(C)nc45)c3Cl)n2C)cc1 -US05445762,2,C1COCCOCCOCCOCCOCCN1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>O=C(N1CCOCCOCCOCCOCCOCC1)C12CC3CC(CC(C3)C1)C2 -US20150057265A1,1,C[C@H]1CNC[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C.O=[N+]([O-])c1cnccc1Cl>>C[C@H]1CN(c2ccncc2[N+](=O)[O-])C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C -US04636521,2,CS(=O)(=O)Cl.NCc1ccc2[nH]ccc2c1>>CS(=O)(=O)NCc1ccc2[nH]ccc2c1 -US05234928,6,CCOC(=O)Cn1c(=S)c2ccccc2n(Cc2ccc(Cl)cc2Cl)c1=O>>O=C(O)Cn1c(=S)c2ccccc2n(Cc2ccc(Cl)cc2Cl)c1=O -US20070197512A1,2,CC(Br)C(=O)Br.Cc1cc(C)c(O)c(N)c1>>Cc1cc(C)c(O)c(NC(=O)C(C)Br)c1 -US07612067B2,3,CCC(CC)c1cc(C)nn2c(-c3sc(Br)cc3Cl)c(C)nc12.[Zn+]c1ccccn1>>CCC(CC)c1cc(C)nn2c(-c3sc(-c4ccccn4)cc3Cl)c(C)nc12 -US05068325,1,COc1cccc(C=CCCl)c1.Nc1nc2c(s1)CCNCC2>>COc1cccc(C=CCN2CCc3nc(N)sc3CC2)c1 -US20150148542A1,2,C1CCNC1.COc1cc(C(=O)O)ccc1Br>>COc1cc(C(=O)N2CCCC2)ccc1Br -US08106064B2,1,COc1ccc(CON=C(c2cc(C)cc(C#N)c2)c2[nH]c(=O)[nH]c(=O)c2C(C)C)cc1.Fc1cc(CBr)ccn1>>COc1ccc(CON=C(c2cc(C)cc(C#N)c2)c2c(C(C)C)c(=O)[nH]c(=O)n2Cc2ccnc(F)c2)cc1 -US07244763B2,1,CC=O.Nc1ccc(Br)cn1>>CCNc1ccc(Br)cn1 -US20050096353A1,6,CCOC(=O)Cn1ccc2ccc(OCc3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc3C)cc21>>Cc1nc(-c2ccc(C(F)(F)F)cc2)cc(C(F)(F)F)c1COc1ccc2ccn(CC(=O)O)c2c1 -US20060252777A1,1,COc1cc2nccc(Cl)c2cc1OC.Oc1ccc(-c2cnc(Nc3ccccc3)nc2)cc1F>>COc1cc2nccc(Oc3ccc(-c4cnc(Nc5ccccc5)nc4)cc3F)c2cc1OC -US08580968B2,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.OC1CN(c2nc3ccc(Br)cc3s2)C1>>Cn1cc(-c2ccc3nc(N4CC(O)C4)sc3c2)cn1 -US20110166146A1,1,Cc1ccc(-c2nc3c(Cl)cc(Cl)cn3c2CCl)cc1.Cc1ccc(=O)[nH]n1>>Cc1ccc(-c2nc3c(Cl)cc(Cl)cn3c2Cn2nc(C)ccc2=O)cc1 -US06689909B1,1,CC(C)[S-].Nc1c([N+](=O)[O-])ccc(F)c1F>>CC(C)Sc1ccc([N+](=O)[O-])c(N)c1F -US20150045559A1,1,BrCc1ccccc1.COc1ccc(C=O)c(O)c1>>COc1ccc(C=O)c(OCc2ccccc2)c1 -US20120258946A1,7,O=Cc1ccc(Br)cc1F>>OCc1ccc(Br)cc1F -US20070037827A1,7,O=[N+]([O-])c1ccc(-c2nc3ccncc3o2)s1>>Nc1ccc(-c2nc3ccncc3o2)s1 -US06127391,6,CC(=O)OCCCNC(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)OC(C)(C)C>>CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)NCCCOC(C)=O -US07858639B2,6,COc1nc(C(F)(F)F)ccc1Cc1nnc2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nn12>>Oc1nc(C(F)(F)F)ccc1Cc1nnc2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nn12 -US20090192153A1,1,CCCCOc1nc(N)c2nc(OC)n(CCCCCBr)c2n1.COC(=O)C1CCNCC1>>CCCCOc1nc(N)c2nc(OC)n(CCCCCN3CCC(C(=O)OC)CC3)c2n1 -US20150038574A1,7,CC1(C)C=C(C=O)C(C)(C)CC1>>CC1(C)C=C(CO)C(C)(C)CC1 -US20150031685A1,1,CC(C)(C)[Si](C)(C)O[C@H]1CCN(C[C@@H](O)c2cccc(OC(F)(F)F)c2)C1.CCN>>CCN[C@H](CN1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1cccc(OC(F)(F)F)c1 -US20090012077A1,6,COCCn1c2c(c3ccccc31)CN(C(=O)OC(C)(C)C)CC2>>COCCn1c2c(c3ccccc31)CNCC2 -US20100113435A1,2,CCOC(=O)Cc1csc(N)n1.COc1cc(C)ccc1S(=O)(=O)Cl>>CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(C)cc2OC)n1 -US20140315944A1,9,CCOC(=O)Cc1cc2ccc(OCc3cccc(Cl)c3)cc2[nH]c1=O.N>>NC(=O)Cc1cc2ccc(OCc3cccc(Cl)c3)cc2[nH]c1=O -US20130336918A1,2,CCN(CC)CCN(C)Cc1cccc(C(=O)O)c1.Cc1ccc(-c2cnc(NC(=O)c3cc(N4CCCCC4)ccc3N)nc2)cc1C>>CCN(CC)CCN(C)Cc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2ncc(-c3ccc(C)c(C)c3)cn2)c1 -US07259183B2,1,CI.COC(=O)c1ccc(C(C)(C)O)cc1>>COC(=O)c1ccc(C(C)(C)OC)cc1 -US06491989B1,1,CCCCCCCCBr.CCCCCCCCC1CCc2c(cc(F)c(F)c2-c2ccc(O)cc2)C1>>CCCCCCCCOc1ccc(-c2c(F)c(F)cc3c2CCC(CCCCCCCC)C3)cc1 -US20110086858A1,2,CC(C)(C)OC(=O)N1CCN(CC(O)CN)CC1.O=C(O)c1ccc(Nc2nc(NCc3ccc(O)cc3)nc(OCC(F)(F)F)n2)cc1>>CC(C)(C)OC(=O)N1CCN(CC(O)CNC(=O)c2ccc(Nc3nc(NCc4ccc(O)cc4)nc(OCC(F)(F)F)n3)cc2)CC1 -US06727245B2,10,Cc1nc2cccnc2n(-c2cccc(NC(=O)c3cc(Cl)cc(Cl)c3)c2)c1=O.O=C1CCC(=O)N1Br>>O=C(Nc1cccc(-n2c(=O)c(CBr)nc3cccnc32)c1)c1cc(Cl)cc(Cl)c1 -US20100105659A1,2,CC(=O)OCC(=O)Cl.Cc1ncccc1Oc1cc(Sc2ccccn2)cnc1Nc1nc(C2CC3CCC(C2)N3)ns1>>CC(=O)OCC(=O)N1C2CCC1CC(c1nsc(Nc3ncc(Sc4ccccn4)cc3Oc3cccnc3C)n1)C2 -US06939871B2,4,C/C=C/C=O.COc1cc(N)c(Br)cc1F>>COc1c(F)cc(Br)c2nc(C)ccc12 -US20120283260A1,2,CNC(=O)N1CCN(CCC(=O)O)CC1.COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccc2n1Cc1ccccn1>>CNC(=O)N1CCN(CCC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4Cc3ccccn3)c2Cl)CC1 -US07939527B2,1,CCOC(=O)C1CCNCC1.Oc1ccc(OCCBr)cc1>>CCOC(=O)C1CCN(CCOc2ccc(O)cc2)CC1 -US20130165436A1,1,CN1CCN(S(=O)(=O)c2cc(Br)cnc2Cl)CC1.C[O-]>>COc1ncc(Br)cc1S(=O)(=O)N1CCN(C)CC1 -US20100190230A1,2,CO.O=C(O)/C=C/c1cccc(F)c1>>COC(=O)/C=C/c1cccc(F)c1 -US04707483,6,COc1cc2c(cc1S(N)(=O)=O)CCNCC2c1ccccc1>>NS(=O)(=O)c1cc2c(cc1O)C(c1ccccc1)CNCC2 -US08217177B2,1,CNC(=O)c1ccc(Br)cc1CO>>CN1Cc2cc(Br)ccc2C1=O -US20130178460A1,1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N.Cn1cnc2c(NC(=O)c3csc4cnc(Cl)nc34)cccc21>>Cn1cnc2c(NC(=O)c3csc4cnc(N[C@@H]5CCOC[C@@H]5NC(=O)OC(C)(C)C)nc34)cccc21 -US20150031686A1,1,CC(=O)c1ccc(C=O)s1.COc1cc(N)ccc1-c1cnco1>>COc1cc(NCc2ccc(C(C)=O)s2)ccc1-c1cnco1 -US06924300B2,1,CCOC(=O)CCCCCC/C(=N\OCc1ccc(O)cc1)c1ccccc1.Cc1oc(-c2ccco2)nc1CCl>>CCOC(=O)CCCCCC/C(=N\OCc1ccc(OCc2nc(-c3ccco3)oc2C)cc1)c1ccccc1 -US20150225367A1,3,CC1(C)OB(c2cnc3[nH]c(=O)oc3c2)OC1(C)C.O=S(=O)(c1ccccc1)n1cc(I)c2ccc(F)cc21>>O=c1[nH]c2ncc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cc2o1 -US20040097503A1,1,COc1ccc(OC)c(N)c1.FC(F)(F)c1cc(Cl)nc(-c2ccccn2)n1>>COc1ccc(OC)c(Nc2cc(C(F)(F)F)nc(-c3ccccn3)n2)c1 -US07923450B2,4,Cc1cn(-c2ccc(NC(N)=S)cc2Cl)cn1.O=C1C(Br)CCCC1c1ccccc1>>Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2Cl)cn1 -US08829052B2,2,COC(=O)c1ccc(S(=O)(=O)Cl)n1C.Nc1ccc(F)c(F)c1Nc1ccc(I)cc1F>>COC(=O)c1ccc(S(=O)(=O)Nc2ccc(F)c(F)c2Nc2ccc(I)cc2F)n1C -US20130203730A1,1,NC(=O)c1cc(F)ccc1Cl.c1c[nH]nn1>>NC(=O)c1cc(-n2ccnn2)ccc1Cl -US04927926,6,CC1(NC(=O)C(F)(F)F)CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4F)c3c2F)C1>>CC1(N)CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4F)c3c2F)C1 -US07265104B2,2,CC(C)Nc1ccc(F)cc1.O=C(Br)CBr>>CC(C)N(C(=O)CBr)c1ccc(F)cc1 -US08049015B2,2,CCNCc1cc(C(F)(F)F)ccc1-c1cncc(CC(=O)OCC)c1.CCOCC(=O)O>>CCOCC(=O)N(CC)Cc1cc(C(F)(F)F)ccc1-c1cncc(CC(=O)OCC)c1 -US07435815B2,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Cc1ccc(N)cc1>>Cc1ccc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1 -US20030176459A1,4,CC(C)(C)c1ccc(N)c(F)c1.CCOC(=O)C(C)C(C)=O>>Cc1nc2c(F)cc(C(C)(C)C)cc2c(O)c1C -US20040138286A1,6,O=C1c2ccccc2C(=O)N1[C@@H]1CC[C@H](Oc2ccc3[nH]ncc3c2)CC1>>N[C@@H]1CC[C@H](Oc2ccc3[nH]ncc3c2)CC1 -US04202832,6,CCOC(=O)CCCSC(=S)NCCCc1ccc(Cl)cc1>>O=C(O)CCCSC(=S)NCCCc1ccc(Cl)cc1 -US08350090B1,6,COc1cccc(CC2=C[C@H](OC(C)=O)CC2=O)c1>>COc1cccc(CC2=C[C@H](O)CC2=O)c1 -US20130296422A1,7,C/C(=C\Cc1c(O)c(Cl)c(C)c(C=O)c1O)CCCCOC(=O)C(C)(C)C>>Cc1c(Cl)c(O)c(CCC(C)CCCCOC(=O)C(C)(C)C)c(O)c1C=O -US20040024210A1,1,CC(C)(C)OC(=O)N1CCN(c2nccc3ccc(Br)cc23)CC1.Sc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCN(c2nccc3ccc(Sc4ccc(Cl)cc4)cc23)CC1 -US06251911B1,2,CCCCCC(=O)OC(=O)CCCCC.Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12>>CCCCCC(=O)Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12 -US05164392,1,CC(=O)N1CCNCC1C.O=C(O)c1cn(C2CC2)c2cc(F)c(F)c(NCc3ccccc3)c2c1=O>>CC(=O)N1CCN(c2cc3c(c(NCc4ccccc4)c2F)c(=O)c(C(=O)O)cn3C2CC2)CC1C -US07560582B2,3,CC(=O)c1ccccc1Cl.COc1ccccc1B(O)O>>COc1ccccc1-c1ccccc1C(C)=O -US20060100248A1,6,COC(=O)c1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1>>O=C(O)c1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1 -US07005440B1,4,NC(=S)c1ccccc1.O=C(CCl)CCl>>ClCc1csc(-c2ccccc2)n1 -US20080009513A1,3,Cc1c2c(n(-c3ccccc3Cl)c1Br)CCN(N1CCCCC1)C2=O.OB(O)c1ccc(O)cc1>>Cc1c2c(n(-c3ccccc3Cl)c1-c1ccc(O)cc1)CCN(N1CCCCC1)C2=O -US20150111870A1,6,Cn1cncc1C(O)(c1ccc2nc(C(F)(F)F)c(C(=O)N3CCCCC3)c(C(F)(F)F)c2c1)C1CCN(C(=O)OC(C)(C)C)CC1>>Cn1cncc1C(O)(c1ccc2nc(C(F)(F)F)c(C(=O)N3CCCCC3)c(C(F)(F)F)c2c1)C1CCNCC1 -US07026331B2,2,CC(=O)OC(C)=O.CNn1c2cnccc2c2ccc(Cl)cc21>>CC(=O)N(C)n1c2cnccc2c2ccc(Cl)cc21 -US07485652B2,6,COC(=O)c1cccc(CN2c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3CC2C)c1>>CC1Cc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2N1Cc1cccc(C(=O)O)c1 -US08153653B2,2,CC(C)(N)CO.COc1cc(C(F)(F)F)cc(OC)c1C(=O)Cl>>COc1cc(C(F)(F)F)cc(OC)c1C(=O)NC(C)(C)CO -US05665753,1,CC(C)C[C@H](C(=O)O)[C@H]1OC(C)(C)OC1=O.Oc1c(F)c(F)c(F)c(F)c1F>>CC(C)C[C@H](C(=O)Oc1c(F)c(F)c(F)c(F)c1F)[C@H]1OC(C)(C)OC1=O -US20100016287A1,1,Cc1nc2cc3c(cc2o1)CCNCC3.O=CCCl>>Cc1nc2cc3c(cc2o1)CCN(CCCl)CC3 -US20090239810A1,2,Cc1ccc(C#N)cc1NC1CCNCC1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>Cc1ccc(C#N)cc1NC1CCN(C(=O)CNC(=O)c2cc(-c3ccccc3)[nH]n2)CC1 -US08034812B2,2,CO/C=C/C(=O)O.Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(N)cn4n3)ccc2C)n(C)n1>>CO/C=C/C(=O)Nc1cn2nc(Oc3ccc(C)c(NC(=O)c4cc(C)nn4C)c3)ccc2n1 -US20100273806A1,3,O=C(O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(Br)cc(OC(F)(F)F)c4)n3)cc21.OB(O)c1ccncc1>>O=C(O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(OC(F)(F)F)cc(-c5ccncc5)c4)n3)cc21 -US20060069110A1,1,CC(C)(N)CNC(=O)OC(C)(C)C.CN(c1ccnc(F)n1)c1ccnc(-c2ccccc2)n1>>CN(c1ccnc(NC(C)(C)CNC(=O)OC(C)(C)C)n1)c1ccnc(-c2ccccc2)n1 -US20100331306A1,10,Cc1nc2c(F)cccc2cc1Br.O=C1CCC(=O)N1Br>>Fc1cccc2cc(Br)c(CBr)nc12 -US20140066455A1,1,C1CC(N2CCNCC2)C1.CCOC(=O)c1ccc(F)cc1>>CCOC(=O)c1ccc(N2CCN(C3CCC3)CC2)cc1 -US09133204B2,2,Cc1ccc(C2(CN)CCCCC2)cn1.O=C(O)c1cn(-c2ncccn2)nc1Cl>>Cc1ccc(C2(CNC(=O)c3cn(-c4ncccn4)nc3Cl)CCCCC2)cn1 -US20030105074A1,1,COc1ccc(CCl)cc1.O=C1NC(=O)c2ccccc21>>COc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 -US07291643B2,3,Cn1c(C#N)ccc1B(O)O.Nc1ccc(Br)cc1OC(F)(F)F>>Cn1c(C#N)ccc1-c1ccc(N)c(OC(F)(F)F)c1 -US20090074715A1,2,COc1ccc2c(c1)C=C(c1ocnc1C(=O)N1CCOCC1)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)O)cc21.NS(=O)(=O)C1CC1>>COc1ccc2c(c1)C=C(c1ocnc1C(=O)N1CCOCC1)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc21 -US20110280808A1,1,N[C@@H](Cc1ccccc1)C(=O)O.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>O=C(O)[C@H](Cc1ccccc1)Nc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] -US20100160335A1,1,CC1CC(=O)NN=C1c1ccc(O)cc1.COc1ccc(C2=NN(CCCCBr)C(=O)CC2C)c2ccc(C)nc12>>COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)CC2C)c2ccc(C)nc12 -US20050154045A1,3,O=C(Nc1ccc(Br)cc1)[C@H]1CN2CCC1CC2.OCc1ccc(Br)cc1F>>O=C(Nc1ccc(-c2ccc(CO)c(F)c2)cc1)[C@H]1CN2CCC1CC2 -US20120129840A1,1,CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1.O=C(NC1CCNCC1)c1ccccc1>>CCCC(C(=O)OC)c1c(C)nc(N2CCC(NC(=O)c3ccccc3)CC2)nc1-c1ccc(C)cc1 -US20120208852A1,9,C[C@](NC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)(C(N)=O)c1cccc(C(F)(F)F)c1>>C[C@@](C#N)(NC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C[C@H](O)C(F)(F)F)c1=O)c1cccc(C(F)(F)F)c1 -US20130102617A1,6,O=C(Nc1cnc(CCOC2CCCCO2)cn1)[C@H](CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)c(C2CC2)c1>>O=C(Nc1cnc(CCO)cn1)[C@H](CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)c(C2CC2)c1 -US20150191464A1,1,CC(O)CN.CCOC(=O)c1cnc(Cl)cc1Cl>>CCOC(=O)c1cnc(Cl)cc1NCC(C)O -US20100022550A1,1,CC(C)C(=O)NC1CCc2c(c3cc(Br)ccc3n2Cc2cccc(F)c2)C1.CNC>>CC(C)C(=O)NC1CCc2c(c3cc(N(C)C)ccc3n2Cc2cccc(F)c2)C1 -US08648068B2,2,CC(C)(C)OC(=O)N1CCCC(N)CC1.Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3O[C@H]3CCOC3)c12>>Cc1c(C(=O)NC2CCCN(C(=O)OC(C)(C)C)CC2)sc2ncnc(Nc3ccc(F)cc3O[C@H]3CCOC3)c12 -US20130293094A1,3,Brc1cc(Br)cc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1.CC1(C)OB(c2cccc(-c3cccc4c3sc3ccccc34)c2)OC1(C)C>>Brc1cc(-c2cccc(-c3cccc4c3sc3ccccc34)c2)cc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1 -US07317009B2,7,CCc1ccc2c(-c3cccc(C#N)c3)c3c(nn12)C(=O)CS3(=O)=O>>CCc1ccc2c(-c3cccc(C#N)c3)c3c(nn12)C(O)CS3(=O)=O -US04558043,7,Cc1cc2c(C)coc2cc1-n1cccc1>>Cc1cc2c(cc1-n1cccc1)OCC2C -US20140323475A1,2,CS(N)(=O)=O.O=C(O)c1cccc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(Cl)cc1F>>CS(=O)(=O)NC(=O)c1cccc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(Cl)cc1F -US20110039889A1,3,CC(C)Oc1ccc(-c2nc(-c3cccc4c(Br)nccc34)no2)cc1Cl.O=C(O)c1cccc(B(O)O)c1>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(-c5cccc(C(=O)O)c5)nccc34)no2)cc1Cl -US20150183763A1,1,Fc1cc(Cl)cc(CCl)c1.OCC(F)(F)F>>Fc1cc(Cl)cc(COCC(F)(F)F)c1 -US20100158850A1,6,COC(=O)CCc1ccc(OCCN=[N+]=[N-])cc1>>[N-]=[N+]=NCCOc1ccc(CCC(=O)O)cc1 -US08143266B2,1,Nc1cccc2c1CC(=O)N2.O=C(CBr)OCc1ccccc1>>O=C1Cc2c(NCC(=O)OCc3ccccc3)cccc2N1 -US20090018134A1,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)cn3)CC2)nc(Cl)n1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)cn3)CC2)nc(-c2ccc(N)cc2)n1 -US20110263651A1,1,CC(C)(C)OC(=O)N1CCC(CCCC(=O)Nc2ccc(Cl)c(Cl)c2)CC1.CCI>>CCN(C(=O)CCCC1CCN(C(=O)OC(C)(C)C)CC1)c1ccc(Cl)c(Cl)c1 -US20140121377A1,1,CC(=O)c1ccc(Br)nc1.c1c[nH]cn1>>CC(=O)c1ccc(-n2ccnc2)nc1 -US20110224155A1,2,N#Cc1c(N)sc2c1CCCC2.O=C(N=C=S)c1ccccc1>>N#Cc1c(NC(=S)NC(=O)c2ccccc2)sc2c1CCCC2 -US08592452B2,1,C[C@H](NC(=O)OCc1ccccc1)C(CCCO)O[Si](C)(C)C(C)(C)C>>C[C@H]1C(O[Si](C)(C)C(C)(C)C)CCCN1C(=O)OCc1ccccc1 -US20110166121A1,6,CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(C(=O)N3CCCC(C(=O)OCC)C3)nc2s1>>CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(C(=O)N3CCCC(C(=O)O)C3)nc2s1 -US20070105880A1,1,CNCCC#N.COc1cc2nc(Cl)nc(N)c2cc1OC>>COc1cc2nc(N(C)CCC#N)nc(N)c2cc1OC -US09034921B2,2,O=C(Cl)c1ccccc1.OCc1cc(C2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)ccc1Cl>>O=C(OCc1cc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)ccc1Cl)c1ccccc1 -US20150133451A1,6,CN(C)CC1CC(=O)N(c2nn(C)cc2NC(=O)c2coc(-c3ccnc(N(CC(F)(F)F)C(=O)OC(C)(C)C)c3)n2)C1>>CN(C)CC1CC(=O)N(c2nn(C)cc2NC(=O)c2coc(-c3ccnc(NCC(F)(F)F)c3)n2)C1 -US05424279,7,CCN(CC)C(=O)n1cc(C=O)c(S(=O)(=O)c2cccc(Cl)c2C)n1>>CCN(CC)C(=O)n1cc(CO)c(S(=O)(=O)c2cccc(Cl)c2C)n1 -US05843983,1,CCCCCCCCOC(=O)N1C[C@H](OC(=O)N(C)C)C[C@H]1CCCl.COc1ccc(CCc2ccccc2)c(O)c1>>CCCCCCCCOC(=O)N1C[C@H](OC(=O)N(C)C)C[C@H]1CCOc1cc(OC)ccc1CCc1ccccc1 -US06083955,2,CO.COc1ccccc1Oc1c(NS(=O)(=O)C=Cc2ccc(C(=O)O)cc2)nc(-c2ncccn2)nc1OC>>COC(=O)c1ccc(C=CS(=O)(=O)Nc2nc(-c3ncccn3)nc(OC)c2Oc2ccccc2OC)cc1 -US20100144745A1,6,C[C@@H]1COCC[C@@H]1NCc1ccccc1>>C[C@@H]1COCC[C@@H]1N -US20090137610A1,10,CCOC(=O)Cc1cccc(C)c1.O=C1CCC(=O)N1Br>>CCOC(=O)Cc1cccc(CBr)c1 -US20040014968A1,2,COc1ccc(C(CC2CCCC2)C(=O)O)cc1.Nc1nccs1>>COc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1 -US20040087552A1,1,CC(C)(CO)C(=O)O.COc1ccc(CCl)cc1>>COc1ccc(COC(=O)C(C)(C)CO)cc1 -US20150175621A1,1,N#Cc1ncc(Br)cn1.Sc1ccccc1>>N#Cc1ncc(Sc2ccccc2)cn1 -US20030220321A1,3,O=C(c1ccccc1)N1CCc2[nH]c3cccc(Br)c3c2CC1.OB(O)c1ccccc1>>O=C(c1ccccc1)N1CCc2[nH]c3cccc(-c4ccccc4)c3c2CC1 -US20130089512A1,9,CC(=O)N[C@H](C)c1ccc(F)cn1>>CC(=O)N[C@H](C)c1ccccn1 -US08501804B2,1,CC(=O)c1cc2cc(O)ccc2o1.CCOc1ccc(CCl)cc1>>CCOc1ccc(COc2ccc3oc(C(C)=O)cc3c2)cc1 -US20140112945A1,2,CC(C)(C)OC(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)O.COc1ccc(C2=NN(C3CCNCC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](CCC(=O)OCc4ccccc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US20090275558A1,2,COc1cc(C)c(S(=O)(=O)Cl)c(C)c1.OCC1CCCCN1>>COc1cc(C)c(S(=O)(=O)N2CCCCC2CO)c(C)c1 -US20130109665A1,9,CC(C)(C)OC(=O)N[C@@H](CC1CC1)C(=O)O.N>>CC(C)(C)OC(=O)N[C@@H](CC1CC1)C(N)=O -US06806365B2,6,COC(=O)[C@H](Cc1ccc(N2C(=O)C(Cc3ccccc3)N(C(C)=O)C2c2ccccc2)cc1)NC(=O)C1(CCCCS(C)(=O)=O)CCCC1>>CC(=O)N1C(Cc2ccccc2)C(=O)N(c2ccc(C[C@H](NC(=O)C3(CCCCS(C)(=O)=O)CCCC3)C(=O)O)cc2)C1c1ccccc1 -US20110294780A1,1,O=C1NC(=O)/C(=C/c2ccc3c(ccn3Cc3ccc(C(F)(F)F)cc3C(F)(F)F)c2)S1.OCCBr>>O=C1S/C(=C\c2ccc3c(ccn3Cc3ccc(C(F)(F)F)cc3C(F)(F)F)c2)C(=O)N1CCO -US20120115916A1,5,CC(=O)c1cccc(Br)c1.OCCO>>CC1(c2cccc(Br)c2)OCCO1 -US20130197217A1,3,CCCC[Sn](/C=C\OCC)(CCCC)CCCC.Clc1ncc(Br)cn1>>CCO/C=C\c1cnc(Cl)nc1 -US08664220B2,3,C=CCC(O)c1c(C)noc1-c1ccc(Br)cc1.Ic1ccc(Cc2ccccc2)cc1>>Cc1noc(-c2ccc(Br)cc2)c1C(O)C/C=C/c1ccc(Cc2ccccc2)cc1 -US08030502B2,7,CC(C)N(C(=O)COCCCCO)C1CCN(Cc2ccccc2)CC1>>CC(C)N(CCOCCCCO)C1CCN(Cc2ccccc2)CC1 -US06352985B1,7,CCOC(=O)c1ccc([N+](=O)[O-])c(N)c1>>CCOC(=O)c1ccc(N)c(N)c1 -US20090275558A1,2,CC(C)(C)OC(=O)N1CCc2sc(C(=O)O)cc2C1.CNOC>>CON(C)C(=O)c1cc2c(s1)CCN(C(=O)OC(C)(C)C)C2 -US08030478B2,6,CC(=O)n1ccc2c(I)ccnc21>>Ic1ccnc2[nH]ccc12 -US20070099928A1,6,COC(=O)C(Cc1ccc(CCOc2ccc(OS(C)(=O)=O)cc2)cc1)SCCc1ccc(OCc2ccccc2)cc1>>COC(=O)C(Cc1ccc(CCOc2ccc(OS(C)(=O)=O)cc2)cc1)SCCc1ccc(O)cc1 -US20140323484A1,7,CC(C)(C)OC(=O)N(CCc1ccc([N+](=O)[O-])cc1Cl)CC1CCCCC1>>CC(C)(C)OC(=O)N(CCc1ccc(N)cc1Cl)CC1CCCCC1 -US04168379,6,CCOC(=O)c1coc(Cc2ccccc2)n1>>O=C(O)c1coc(Cc2ccccc2)n1 -US20100029643A1,7,CCNc1cc(OC)ncc1[N+](=O)[O-]>>CCNc1cc(OC)ncc1N -US20080004321A1,1,CCCc1c(O)ccc(C(C)=O)c1O.COC(=O)c1cccc(CO)n1>>CCCc1c(OCc2cccc(C(=O)OC)n2)ccc(C(C)=O)c1O -US20120316337A1,3,CCCC[Mg+].O=C(O)c1ccc2ccccc2c1F>>CCCCc1c(C(=O)O)ccc2ccccc12 -US20080207708A1,4,CC(C)COc1ccc(Cl)cc1Nc1nc(C(=O)O)cs1.COC(=O)c1ccc(N)c(N)c1>>COC(=O)c1ccc2[nH]c(-c3csc(Nc4cc(Cl)ccc4OCC(C)C)n3)nc2c1 -US20100113410A1,3,COc1c(C)cnc(Cn2nc3cc(OS(=O)(=O)C(F)(F)F)c4c-3c(n2)C(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)=NSC4)c1C.OB(O)c1cncnc1>>COc1c(C)cnc(Cn2nc3cc(-c4cncnc4)c4c-3c(n2)C(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)=NSC4)c1C -US04032322,9,CC(C)C(Cl)=C(C#N)C#N.[NH4+]>>CC(C)C(N)=C(C#N)C#N -US20110275797A1,6,COC(=O)c1cc(N2CCOCC2)ccc1OCc1ccccc1>>O=C(O)c1cc(N2CCOCC2)ccc1OCc1ccccc1 -US07803822B2,2,CCNC(=O)c1ccc(-n2cc(C(=O)O)nn2)c(OCCCc2ccccc2)c1.COCCN>>CCNC(=O)c1ccc(-n2cc(C(=O)NCCOC)nn2)c(OCCCc2ccccc2)c1 -US20130085131A1,1,COC(=O)c1c(OC)c(C(C)N)nc2ccc(F)cc12.N#Cc1c(N)ncnc1Cl>>COC(=O)c1c(OC)c(C(C)Nc2ncnc(N)c2C#N)nc2ccc(F)cc12 -US08232278B2,1,CCN.Fc1ccc(-c2ccc3nc(Cl)nc(Cl)c3n2)cc1>>CCNc1nc(Cl)nc2ccc(-c3ccc(F)cc3)nc12 -US20100130497A1,1,CCC#CCBr.COc1cc(C=O)ccc1O>>CCC#CCOc1ccc(C=O)cc1OC -US20060116368A1,2,Nc1nccc2cccnc12.O=C(O)C1CCN(c2ccc3ccccc3c2)CC1>>O=C(Nc1nccc2cccnc12)C1CCN(c2ccc3ccccc3c2)CC1 -US20070197604A1,2,CS(=O)(=O)Cl.Cc1oc(-c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)nc1CCCO>>Cc1oc(-c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)nc1CCCOS(C)(=O)=O -US20080004309A1,4,CCOC(=O)C(Cl)C(C)=O.COc1cccc(C(N)=S)c1>>CCOC(=O)c1sc(-c2cccc(OC)c2)nc1C -US20130029961A1,7,CC1(C)OCC(c2ccc([N+](=O)[O-])cn2)O1>>CC1(C)OCC(c2ccc(N)cn2)O1 -US08227604B2,1,O=C1c2ccccc2C(=O)N1CCBr.c1ccc(N2CCNCC2)cc1>>O=C1c2ccccc2C(=O)N1CCN1CCN(c2ccccc2)CC1 -US06518260B1,3,CCOC(=O)C(Cc1ccc(Br)cc1)CP(=O)(O)C(C)NC(=O)OCc1ccccc1.OB(O)c1ccccc1>>CCOC(=O)C(Cc1ccc(-c2ccccc2)cc1)CP(=O)(O)C(C)NC(=O)OCc1ccccc1 -US20150166558A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=C1CCN(Cc2ccccc2)CC1>>CCOC(=O)C=C1CCN(Cc2ccccc2)CC1 -US20100076015A1,2,CC(C)(C)OC(=O)N[C@@H](CC1CCCC2CCCCC21)C(=O)O.NCc1ccc(N)nc1>>CC(C)(C)OC(=O)N[C@@H](CC1CCCC2CCCCC21)C(=O)NCc1ccc(N)nc1 -US06506749B2,5,NC1CCN(Cc2ccccc2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NC1CCN(Cc2ccccc2)CC1)C(F)(F)F -US20070203218A1,4,CC(C)S(=O)(=O)NC1Cc2ccc(-c3cccc(CN)c3)cc2C1.O=C(Cl)CCCCl>>CC(C)S(=O)(=O)NC1Cc2ccc(-c3cccc(CN4CCCC4=O)c3)cc2C1 -US20120322788A1,8,CC(C)(Cc1cccc(CO)c1)NC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(OC(=O)OC(C)(C)C)c2[nH]c(=O)ccc12>>CC(C)(Cc1cccc(C=O)c1)NC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(OC(=O)OC(C)(C)C)c2[nH]c(=O)ccc12 -US20120035134A1,2,C1COCCN1.NS(=O)(=O)c1ccc(N[C@@H](CSc2ccccc2)CC(=O)O)c(S(=O)(=O)C(F)(F)F)c1>>NS(=O)(=O)c1ccc(N[C@@H](CSc2ccccc2)CC(=O)N2CCOCC2)c(S(=O)(=O)C(F)(F)F)c1 -US20040235647A1,1,C=C(C)C.OCCCCl>>CC(C)(C)OCCCCl -US05443970,7,C[SiH](C)OCC1=C(O)CC(C(C)(C)C)OC1=O>>C[SiH](C)OCC1C(=O)OC(C(C)(C)C)CC1O -US20040204409A1,7,COC(=O)c1ccc2cnc(CCc3ccccc3)n2c1>>OCc1ccc2cnc(CCc3ccccc3)n2c1 -US20040192680A1,3,CCOP(=O)(CC(=O)NC1CCCCC1O)OCC.O=Cc1ccccc1Sc1ccc(F)cc1>>O=C(/C=C/c1ccccc1Sc1ccc(F)cc1)NC1CCCCC1O -US07745642B2,1,CNC1(C(NC(=O)c2cccc(C(F)(F)F)c2Cl)c2ccccc2)CCCC1.O=CC1CC1>>CN(CC1CC1)C1(C(NC(=O)c2cccc(C(F)(F)F)c2Cl)c2ccccc2)CCCC1 -US08669398B2,2,CC(=O)Cl.CC(=O)OC1CC(C)(C)N(OC(=NC2CCCCC2)NC2CCCCC2)C(C)(C)C1>>CC(=O)OC1CC(C)(C)N(OC(=NC2CCCCC2)N(C(C)=O)C2CCCCC2)C(C)(C)C1 -US05189041,2,COC(=O)c1cccc2c1cc1n2CCCC1.N[C@@H]1CN2CCC1CC2>>O=C(N[C@@H]1CN2CCC1CC2)c1cccc2c1cc1n2CCCC1 -US06218385B1,1,C[O-].O=[N+]([O-])c1c(Cl)ncnc1N1CCc2ccccc2CC1>>COc1ncnc(N2CCc3ccccc3CC2)c1[N+](=O)[O-] -US20090221645A1,7,O=CC1=C(c2ccc(Cl)c(Cl)c2)N2CCN=C2S1>>OCC1=C(c2ccc(Cl)c(Cl)c2)N2CCN=C2S1 -US20120178736A1,1,O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1.OC1CCN(C2CNC2)CC1>>OC1CCN(C2CN(Cc3cc4nc(Cl)nc(N5CCOCC5)c4s3)C2)CC1 -US20050209290A1,7,C=CCOc1ccc(C=O)c(C)c1>>C=CCOc1ccc(CO)c(C)c1 -US20150266874A1,2,Nc1c[nH]nc1-c1nc2ccccc2s1.O=C(Cl)C1CCOCC1>>O=C(Nc1c[nH]nc1-c1nc2ccccc2s1)C1CCOCC1 -US06951879B2,1,BrCCCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1.C#CCNC>>C#CCN(C)CCCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1 -US05763615,7,COC(OC)C(C)Nc1cc(OCc2ccccc2)ccc1[N+](=O)[O-]>>COC(OC)C(C)Nc1cc(OCc2ccccc2)ccc1N -US08163793B2,1,COC(=O)C1CC(O)CN1.O=[N+]([O-])c1ccccc1Cl>>COC(=O)[C@@H]1C[C@H](O)CN1c1ccccc1[N+](=O)[O-] -US20100273770A1,6,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)C(CO)CO4)no2)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CNC(CO)CO4)no2)cc1Cl -US20090258888A1,6,CC(C)(C)OC(=O)NCCCc1cc(Nc2ccc(Oc3ccnc(C(F)(F)F)c3)cc2)nc(N)n1>>NCCCc1cc(Nc2ccc(Oc3ccnc(C(F)(F)F)c3)cc2)nc(N)n1 -US03997536,9,CCCc1ccc(-c2ncc(C#N)c(Cl)n2)cc1>>CCCc1ccc(-c2ncc(C#N)cn2)cc1 -US07772183B2,2,CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(O)CN2C1=O.O=C(Cl)c1ccc2c(c1)OCO2>>CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(OC(=O)c3ccc4c(c3)OCO4)CN2C1=O -US20130196974A1,2,CC(=O)OC(C)=O.c1ccc2c(c1)CCCNC2>>CC(=O)N1CCCc2ccccc2C1 -US20130131018A1,7,CCOC(C/N=C/c1cccc(O)c1O)OCC>>CCOC(CNCc1cccc(O)c1O)OCC -US20040192686A1,1,CCNCC.Nc1nc2cc(F)ccc2[n+]([O-])n1>>CCN(CC)c1ccc2c(c1)nc(N)n[n+]2[O-] -US20150025087A1,1,COC(=O)c1cc(F)c(C)nc1Cl.C[O-]>>COC(=O)c1cc(F)c(C)nc1OC -US20040198732A1,1,CN(C)C1CCNC1.Cn1c(CO)cc2cc(NC(=O)Nc3ccc(Oc4ccccc4)cc3)ccc21>>CN(C)C1CCN(Cc2cc3cc(NC(=O)Nc4ccc(Oc5ccccc5)cc4)ccc3n2C)C1 -US20140038991A1,2,CCOC(=O)/C=C/c1c(C)nc(N)nc1N[C@@H]1CC[C@@H](OCCO)CC1>>Cc1nc(N)nc2c1ccc(=O)n2[C@@H]1CC[C@@H](OCCO)CC1 -US20130035446A1,2,O=C(O)/C=C/c1ccc(C(F)(F)Oc2ccc(OCCCC(F)(F)F)cc2)cc1.O=[N+]([O-])c1ccc(CCO)c([N+](=O)[O-])c1>>O=C(/C=C/c1ccc(C(F)(F)Oc2ccc(OCCCC(F)(F)F)cc2)cc1)OCCc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] -US06727264B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.O=Cc1ccc2nsnc2c1>>CC(C)C(=O)Nc1cccc(C2CCN(Cc3ccc4nsnc4c3)CC2)c1 -US07067518B2,2,CC1(C(=O)Cl)CCCCC1.CN[C@H](Cc1ccccn1)CN1CCN(c2ccccc2OC)CC1>>COc1ccccc1N1CCN(C[C@@H](Cc2ccccn2)N(C)C(=O)C2(C)CCCCC2)CC1 -US07598258B2,7,O=[N+]([O-])c1ccccc1Oc1ccnc2ccccc12>>Nc1ccccc1Oc1ccnc2ccccc12 -US20070197558A1,1,BrCc1ccccc1.O=[N+]([O-])c1cc(O)ccc1Cl>>O=[N+]([O-])c1cc(OCc2ccccc2)ccc1Cl -US03957763,4,CC(=O)OO.CC(C)=CCCC(C)=CCOc1ccc2c(c1)OCCC2>>CC(=CCOc1ccc2c(c1)OCCC2)CCC1OC1(C)C -US05137920,7,COC(=O)c1ccc(/C=C\CCCCCN(C)C)cc1>>COC(=O)c1ccc(CCCCCCCN(C)C)cc1 -US07795283B2,7,COC[C@@H](C)Oc1cccc([N+](=O)[O-])c1>>COC[C@@H](C)Oc1cccc(N)c1 -US20040176605A1,6,O=C(CCc1cccnc1)NCCCCC1CCN(C(c2ccccc2)c2ccccc2)CC1>>O=C(CCc1cccnc1)NCCCCC1CCNCC1 -US20100093763A1,8,COc1ccccc1C(O)c1cc2c(N)nc(-c3cccc(OC(F)(F)F)c3)nc2s1>>COc1ccccc1C(=O)c1cc2c(N)nc(-c3cccc(OC(F)(F)F)c3)nc2s1 -US07317125B2,3,CC(C)N(NC(=O)c1ccccc1)C(=O)CSc1ccccc1Br.COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccccc2SCC(=O)N(NC(=O)c2ccccc2)C(C)C)cc1 -US20080200485A1,6,COC(=O)c1nc(Sc2ccc(NC(=O)C3CC3)cc2)nc(Nc2cc(C)[nH]n2)c1N>>Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CC4)cc3)nc(C(=O)O)c2N)n[nH]1 -US07375227B2,2,CN(Cc1ccccc1)c1cc(N=C=O)ccn1.NCCN1CCC(O)(Cc2ccccc2)CC1>>CN(Cc1ccccc1)c1cc(NC(=O)NCCN2CCC(O)(Cc3ccccc3)CC2)ccn1 -US20150203499A1,6,COC(=O)/C=C/c1c[nH]c2ncnc(OCC(C)C)c12>>CC(C)COc1ncnc2[nH]cc(/C=C/C(=O)O)c12 -US08470828B2,2,CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1>>CC(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1 -US06482849B1,1,ClCc1c(Cl)cccc1Cl.N[C@@H](Cc1c[nH]cn1)C(=O)O>>N[C@@H](Cc1cn(Cc2c(Cl)cccc2Cl)cn1)C(=O)O -US20100041891A1,1,CI.O=c1[nH]cc(Br)cc1Cl>>Cn1cc(Br)cc(Cl)c1=O -US04661603,7,Cc1cc(C)c(C(=O)c2cccc(-n3ccnc3)c2)c(C)c1>>Cc1cc(C)c(C(O)c2cccc(-n3ccnc3)c2)c(C)c1 -US20150141400A1,6,CCOC(=O)c1cc(Br)c(CN2CCN(C(=O)OC(C)(C)C)CC2)cc1N>>CC(C)(C)OC(=O)N1CCN(Cc2cc(N)c(C(=O)O)cc2Br)CC1 -US06235731B1,6,CC(C)(C)OC(=O)N1CCN(CCCNC(=O)C2=Cc3cnc4cccc(n34)S2)C(=O)C1>>O=C(NCCCN1CCNCC1=O)C1=Cc2cnc3cccc(n23)S1 -US20120035164A1,2,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CN)c4)cc23)CC1.O=C(O)C1CCOC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CNC(=O)C5CCOC5)c4)cc23)CC1 -US07115615B2,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCCC1.Nc1c(Br)ccc2c1OCO2>>COc1cc2c(Nc3c(Br)ccc4c3OCO4)ncnc2cc1OCCCN1CCCCC1 -US20130196974A1,1,CC(N)=O.Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(Cl)c2c1>>CC(=O)Nc1cc(N2CCS(=O)(=O)c3ccccc3C2)nc2ccc(C)cc12 -US05480899,1,COC(=O)c1ccc(O)cc1.O=C1OC(CCl)CN1c1ccc(Cl)cc1>>COC(=O)c1ccc(OCC2CN(c3ccc(Cl)cc3)C(=O)O2)cc1 -US07683056B2,1,Cc1cc(F)ccc1-c1cc(Cl)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.OC[C@H]1CN2CCC[C@@H]2CN1>>Cc1cc(F)ccc1-c1cc(N2C[C@H]3CCCN3C[C@@H]2CO)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20140378487A1,1,N#Cc1cncc(O)c1.O=Cc1ccc(F)c(F)c1>>N#Cc1cncc(Oc2ccc(C=O)cc2F)c1 -US07091199B1,1,BrCCOc1cccc(-c2noc3ccsc23)c1.NCc1ccccc1>>c1ccc(CNCCOc2cccc(-c3noc4ccsc34)c2)cc1 -US08420695B2,1,CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(N)s2)c(F)c1.Ic1ccccc1>>CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(Nc3ccccc3)s2)c(F)c1 -US20150018347A1,2,CC(C)[C@@H](N)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1.O=C1NCC2(CC[C@@H](C(=O)O)C2)O1>>CC(C)[C@@H](NC(=O)[C@@H]1CCC2(CNC(=O)O2)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 -US06323213B1,9,COC(=O)c1cc(F)c(F)c(Br)c1F.N#C[Cu]>>COC(=O)c1cc(F)c(F)c(C#N)c1F -US07851473B2,2,O=C(Nc1nc2ccccc2s1)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1nc2ccccc2s1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 -US06492360B1,2,COC(=O)CCCc1nnc(-c2nccs2)c2cc(OC)ccc12.NO>>COc1ccc2c(CCCC(=O)NO)nnc(-c3nccs3)c2c1 -US06753334B2,2,COC(=O)c1cnn(-c2ccc(S(C)(=O)=O)cc2Cl)c1C1CC1.N=C(N)N>>CS(=O)(=O)c1ccc(-n2ncc(C(=O)NC(=N)N)c2C2CC2)c(Cl)c1 -US20130116231A1,1,CC(C)(C)OC(=O)N1CC(I)C1.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC(C)(C)OC(=O)N1CC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)C1 -US20030144326A1,2,CCCCCCNC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(N2CCC3(CC2)OCCO3)cc1>>CCCCCCNC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(N3CCC4(CC3)OCCO4)cc2)cc1 -US20120232096A1,1,CSc1ccc(Br)cc1.Cc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)(C)C2>>CSc1ccc(N2CCN(c3c(C)c(C)c4c(c3C)CC(C)(C)O4)CC2)cc1 -US20120065202A1,3,CC1(C)OB(c2ccc(NC(=O)Nc3cccc(O)c3)cc2)OC1(C)C.CCOC(=O)N1Cc2nc(Cl)nc(N3CCOC[C@@H]3C)c2C1>>CCOC(=O)N1Cc2nc(-c3ccc(NC(=O)Nc4cccc(O)c4)cc3)nc(N3CCOC[C@@H]3C)c2C1 -US20120202806A1,1,CC(C)N.COc1cnc(-c2cnccn2)nc1Cl>>COc1cnc(-c2cnccn2)nc1NC(C)C -US07220744B2,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.O=S(=O)(c1ccccn1)c1cnc(N2CCNCC2)s1>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(S(=O)(=O)c3ccccn3)s2)CC1 -US20060166983A1,2,CS(N)(=O)=O.Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1COc1ccc2c(ccn2CC(=O)O)c1>>Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1COc1ccc2c(ccn2CC(=O)NS(C)(=O)=O)c1 -US04886809,1,CC(=O)NC1CCNCC1.COC(OC)c1cc(Cl)ccc1[N+](=O)[O-]>>COC(OC)c1cc(N2CCC(NC(C)=O)CC2)ccc1[N+](=O)[O-] -US20070249847A1,2,COC(=O)CN.O=C(O)c1cc(OC(F)(F)F)ccc1[N+](=O)[O-]>>COC(=O)CNC(=O)c1cc(OC(F)(F)F)ccc1[N+](=O)[O-] -US20150225404A1,1,Fc1ncccc1-c1cc(Cl)nc2c1CCCC2.OCc1cccc(F)n1>>Fc1cccc(COc2cc(-c3cccnc3F)c3c(n2)CCCC3)n1 -US07745445B2,10,COc1ccc(-c2cc(-c3ccc(OC)cc3)nc(C)n2)cc1.O=C1CCC(=O)N1Br>>COc1ccc(-c2cc(-c3ccc(OC)cc3)nc(CBr)n2)cc1 -US20060166989A1,2,COC(=O)C(N)Cc1ccccc1.O=C(O)c1ccc2cc(O)ccc2c1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2cc(O)ccc2c1 -US20090023725A1,4,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(F)c(C=O)c1.Cc1cc(NN)nc(C)n1>>Cc1cc(-n2ncc3cc(-c4cc(C(=O)NC5CC5)cc(F)c4C)ccc32)nc(C)n1 -US20130317017A1,1,Clc1nc(N2CCOCC2)c2sc(CN3CCNCC3)cc2n1.O=Cc1ncc[nH]1>>Clc1nc(N2CCOCC2)c2sc(CN3CCN(Cc4ncc[nH]4)CC3)cc2n1 -US20080076774A1,1,CCOCc1cc(NCCN2CCCC2)c(C)c(N2CCNCC2)c1.Clc1ncnc2[nH]nc(Br)c12>>CCOCc1cc(NCCN2CCCC2)c(C)c(N2CCN(c3ncnc4[nH]nc(Br)c34)CC2)c1 -US05532242,2,Nc1ccccc1.O=C(Cl)C1CCCCC1>>O=C(Nc1ccccc1)C1CCCCC1 -US20140121187A1,7,CCNC(=O)Oc1cc(C(C)C)ccc1C1(NC(C)=O)C(=O)c2cccc([N+](=O)[O-])c2C1=O>>CCNC(=O)Oc1cc(C(C)C)ccc1C1(NC(C)=O)C(=O)c2cccc(N)c2C1=O -US06500840B2,2,N[C@H]1CN2CCC1CC2.O=C(O)c1cnc(Sc2ccccc2)s1>>O=C(N[C@H]1CN2CCC1CC2)c1cnc(Sc2ccccc2)s1 -US07091232B2,3,CC(C)C[Mg+].OC1CCC=C1Br>>CC(C)CC1=CCCC1O -US07935702B2,1,NC(=O)c1cnc(-c2cnc3c(Cl)ccnc3n2)c(C(F)(F)F)c1.Nc1cnc(C(F)(F)F)cn1>>NC(=O)c1cnc(-c2cnc3c(Nc4cnc(C(F)(F)F)cn4)ccnc3n2)c(C(F)(F)F)c1 -US08450322B2,7,O=[N+]([O-])c1cnc2ccc(N3CCCCC3c3cccc(F)c3)nn12>>Nc1cnc2ccc(N3CCCCC3c3cccc(F)c3)nn12 -US06166006,1,CI.O=C(Nc1cccc(CN2CCCCC2)c1)C1=Cc2cc(-c3ccccc3)ccc2CC1>>C[N+]1(Cc2cccc(NC(=O)C3=Cc4cc(-c5ccccc5)ccc4CC3)c2)CCCCC1 -US07179823B1,6,CCOC(=O)CCc1cn(Cc2ccccc2)nc1OCC>>CCOC(=O)CCc1c[nH]nc1OCC -US07435744B2,2,O=C(O)C(=O)Nc1cccc([N+](=O)[O-])c1.c1ccc(CC2CCNCC2)cc1>>O=C(Nc1cccc([N+](=O)[O-])c1)C(=O)N1CCC(Cc2ccccc2)CC1 -US20140200227A1,1,CC(C)(C)OC(=O)N[C@H]1CCCNC1.O=[N+]([O-])c1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1Cl>>CC(C)(C)OC(=O)N[C@H]1CCCN(c2c([N+](=O)[O-])cnc3c2ccn3S(=O)(=O)c2ccccc2)C1 -US20140371199A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(O)c1ccc(-c2cn3c(-c4ccc(Cl)cc4)cnc3cn2)cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(Cl)cc5)cnc4cn3)cc2)CC1 -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1ccc(Cl)cc1F>>CCCC(C(=O)O)c1c(C)nc(N2CCCCC2)nc1-c1ccc(Cl)cc1F -US06162808,10,CCOC(=O)c1cnc(C)s1.O=C1CCC(=O)N1Br>>CCOC(=O)c1cnc(CBr)s1 -US20090182001A1,6,COc1ccc2cc(I)c(NC(=O)OC(C)(C)C)cc2c1>>COc1ccc2cc(I)c([NH3+])cc2c1 -US20140107097A1,3,CON(C)C(=O)c1ccc2oc(C)nc2c1.Cn1cncc1Br>>Cc1nc2cc(C(=O)c3cncn3C)ccc2o1 -US20050131014A1,1,N#Cc1cc(F)cc(Br)c1.Oc1cccc(-c2c(Cc3ccccc3)cnc3c(Cl)cccc23)c1>>N#Cc1cc(Br)cc(Oc2cccc(-c3c(Cc4ccccc4)cnc4c(Cl)cccc34)c2)c1 -US08623877B2,2,Brc1ccc2c(c1)CCNCC2.COC(=O)Cl>>COC(=O)N1CCc2ccc(Br)cc2CC1 -US07858640B2,6,COC(=O)COc1ccc(F)c2nc(OC(F)F)c(Cc3ccc(Cl)cc3)c(C)c12>>Cc1c(Cc2ccc(Cl)cc2)c(OC(F)F)nc2c(F)ccc(OCC(=O)O)c12 -US06949542B2,2,CCOc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F.Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)c(C)cn1>>CCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cc(C)ncc3C)c2)cc1C(F)(F)F -US20090275592A1,6,CC(C)(C)OC(=O)N[C@H](CCc1cc(-c2ccc3cnccc3c2)no1)Cc1ccccc1>>N[C@H](CCc1cc(-c2ccc3cnccc3c2)no1)Cc1ccccc1 -US07572805B2,1,C=O.CCc1cc(Cl)c2c(c1)[C@H]1CNC[C@@H]1NC2=O>>CCc1cc(Cl)c2c(c1)[C@H]1CN(C)C[C@@H]1NC2=O -US20030105092A1,7,CCOC(=O)Cc1cccc(C#N)c1>>CCOC(=O)Cc1cccc(CN)c1 -US20140200197A1,6,CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cccc(F)c1OC[C@@H]1CN(C(=O)OC(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)CO1)C(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cccc(F)c1OC[C@@H]1CN(C(=O)OC(C)(C)C)[C@H](CO)CO1)C(c1ccc(F)cc1)c1ccc(F)cc1 -US04735942,1,CI.O=C1NCCN1c1ccc([N+](=O)[O-])cc1>>CN1CCN(c2ccc([N+](=O)[O-])cc2)C1=O -US20090197868A1,6,CCOc1cc2c(cc1Br)C(C)CN(C(=O)C(F)(F)F)CC2>>CCOc1cc2c(cc1Br)C(C)CNCC2 -US20090264425A1,2,Cc1nc(S(N)(=O)=O)ccc1N.O=C(Cl)CCl>>Cc1nc(S(N)(=O)=O)ccc1NC(=O)CCl -US04344948,7,O=C(CN1CCC(N2C(=O)NCc3ccccc32)CC1)c1ccc2c(c1)OCO2>>O=C1NCc2ccccc2N1C1CCN(CC(O)c2ccc3c(c2)OCO3)CC1 -US20090170914A1,2,Nc1ccc2nc(NC(=O)c3ccccc3)sc2c1.O=C(O)C12CC3CC(CC(C3)C1)C2>>O=C(Nc1nc2ccc(NC(=O)C34CC5CC(CC(C5)C3)C4)cc2s1)c1ccccc1 -US20120157452A1,6,COC(=O)c1c(Cl)ccc(OCc2ccccc2)c1F>>O=C(O)c1c(Cl)ccc(OCc2ccccc2)c1F -US05268375,10,Cc1ccc(-c2ccccc2[N+](=O)[O-])cc1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1ccccc1-c1ccc(CBr)cc1 -US04753941,2,CSc1ccc(C(=O)O)s1.Nc1ccc2ccc(Cl)nc2n1>>CSc1ccc(C(=O)Nc2ccc3ccc(Cl)nc3n2)s1 -US20100069362A1,2,CN.CN(CC(=O)O)Cc1ccc(CCn2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)cc1>>CNC(=O)CN(C)Cc1ccc(CCn2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)cc1 -US08378092B2,1,Cc1c(Br)cccc1Br.SCc1ccccc1>>Cc1c(Br)cccc1SCc1ccccc1 -US07160891B2,1,OCCCN1CCCC1.Oc1cc(OC2CCOCC2)c2c(Cl)ncnc2c1>>Clc1ncnc2cc(OCCCN3CCCC3)cc(OC3CCOCC3)c12 -US20020049148A1,1,CN1CCN(C)CC(C)(N)C1.O=Cc1ccccn1>>CN1CCN(C)CC(C)(NCc2ccccn2)C1 -US20120135961A1,6,CC(=O)NC[C@H]1CN(c2ccc(OCC3(OC(=O)CCC(=O)OCc4ccccc4)CCN(c4nc5c(cc4F)c(=O)c(C(=O)O)cn5C4CC4)CC3)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(OCC3(OC(=O)CCC(=O)O)CCN(c4nc5c(cc4F)c(=O)c(C(=O)O)cn5C4CC4)CC3)c(F)c2)C(=O)O1 -US08697883B2,7,CC(C)(C)OC(=O)N1C[C@H]2CCC(=O)[C@H]2C1>>CC(C)(C)OC(=O)N1C[C@H]2CC[C@@H](O)[C@H]2C1 -US20040138199A1,7,O=[N+]([O-])c1cc(Br)ccc1O>>Nc1cc(Br)ccc1O -US20130324506A1,3,CC1(C)OB(Cc2ccccc2)OC1(C)C.CN1CCC(OC2c3cccc(Br)c3CCn3cc(-c4ccccc4)nc32)CC1>>CN1CCC(OC2c3cccc(Cc4ccccc4)c3CCn3cc(-c4ccccc4)nc32)CC1 -US04621086,7,COc1ccc(COc2ccc([N+](=O)[O-])cc2)cc1>>COc1ccc(COc2ccc(N)cc2)cc1 -US04556672,2,NC(=O)Nc1ccc(Cl)cc1CC(=O)O>>NC(=O)N1C(=O)Cc2cc(Cl)ccc21 -US08802659B2,1,CC(C)(C)C1CCC(Oc2ccc3sc(C=O)nc3c2)CC1.O=C(O)[C@@H]1CCNC1>>CC(C)(C)C1CCC(Oc2ccc3sc(CN4CC[C@@H](C(=O)O)C4)nc3c2)CC1 -US20060205718A1,2,CC(C)(C)OC(=O)N1CCC(Nc2nc3cc(N)ccc3o2)CC1.O=C(Cl)C1CCC1>>CC(C)(C)OC(=O)N1CCC(Nc2nc3cc(NC(=O)C4CCC4)ccc3o2)CC1 -US06770637B2,1,Cc1ccccc1-c1cc(I)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.N#Cc1cccc(O)c1>>Cc1ccccc1-c1cc(Oc2cccc(C#N)c2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US08461175B2,3,C[Si](C)(C)CCOCn1nc2c(nc(-c3c(F)cccc3F)c3cc(I)ccc32)c1Br.OB(O)c1cn[nH]c1>>C[Si](C)(C)CCOCn1nc2c(nc(-c3c(F)cccc3F)c3cc(-c4cn[nH]c4)ccc32)c1Br -US20080214545A1,1,CC(C)(C)OC(=O)N1CCC(CCO)CC1.CC(C)(C)c1cc(N)n(-c2ccc(O)cc2)n1>>CC(C)(C)OC(=O)N1CCC(CCOc2ccc(-n3nc(C(C)(C)C)cc3N)cc2)CC1 -US05602277,6,CCOC(=O)c1ccc(NC(=O)C(C)C)c(N)c1>>CC(C)C(=O)Nc1ccc(C(=O)O)cc1N -US04888048,4,C[S+](C)(C)=O.O=C(COC1CCCCO1)c1ccc(Cl)cc1>>Clc1ccc(C2(COC3CCCCO3)CO2)cc1 -US20150011527A1,6,CCCCCCCOc1ccc(-c2cnc(-c3ccc(C[C@H](NC(=O)c4ccc(C(C)(C)C)cc4)C(=O)N[C@@H](CC(=O)OCc4ccccc4)C(=O)OC(C)(C)C)cc3)nc2)cc1>>CCCCCCCOc1ccc(-c2cnc(-c3ccc(C[C@H](NC(=O)c4ccc(C(C)(C)C)cc4)C(=O)N[C@@H](CC(=O)O)C(=O)OC(C)(C)C)cc3)nc2)cc1 -US20110112120A9,6,CCCc1nc(C)n(Cc2ccccc2C(=O)OC)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1>>CCCc1nc(C)n(Cc2ccccc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1 -US20120046290A1,2,CC(=O)Cl.Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(Cc2ccc(N)cc2)cc1>>CC(=O)Nc1ccc(Cc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3C)cc2)cc1 -US04931452,1,C[O-].FC(F)(F)c1cnc(Cl)c(Br)c1>>COc1ncc(C(F)(F)F)cc1Br -US03941803,1,O=C(c1ccccc1)c1cc(F)ccc1-n1ccnc1CO.O=C1NC(=O)c2ccccc21>>O=C(c1ccccc1)c1cc(F)ccc1-n1ccnc1CN1C(=O)c2ccccc2C1=O -US20070254880A1,2,CCCS(=O)(=O)N1CCC(CN)(c2ncccc2Br)CC1.O=C(Cl)c1ccc(Cl)cc1Cl>>CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2ncccc2Br)CC1 -US20080255124A1,1,O=[N+]([O-])c1ccc(Cl)nc1.OCc1ccccc1>>O=[N+]([O-])c1ccc(OCc2ccccc2)nc1 -US20150183801A1,3,CC1(C)OB(c2cnc(Cl)c(F)c2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cnc(Cl)c(F)c2)c1 -US20070054924A1,2,COC(=O)c1ccc(Cl)c(OCC(=O)O)c1.Cc1c(OC2CCN(C[C@H](O)CN)CC2)ccc(Cl)c1Cl>>COC(=O)c1ccc(Cl)c(OCC(=O)NC[C@@H](O)CN2CCC(Oc3ccc(Cl)c(Cl)c3C)CC2)c1 -US05972966,1,N#Cc1ccc(Cn2cncc2CCNC(=O)[C@@H]2CCCCN2)cc1.O=CC(c1ccccc1)c1ccccc1>>N#Cc1ccc(Cn2cncc2CCNC(=O)[C@@H]2CCCCN2CC(c2ccccc2)c2ccccc2)cc1 -US05321029,1,CCCCl.O=c1c2[nH]cnc2n(CC2CCC2)c(=O)n1CC1CCC1>>CCCn1cnc2c1c(=O)n(CC1CCC1)c(=O)n2CC1CCC1 -US20120232033A1,1,CC(C)(C)OC(=O)NC(C(=O)c1ccc(O)cc1)c1ccc(Cl)c(Cl)c1.OCC1CCOCC1>>CC(C)(C)OC(=O)NC(C(=O)c1ccc(OCC2CCOCC2)cc1)c1ccc(Cl)c(Cl)c1 -US20120189546A1,6,Cc1ccc(S(=O)(=O)O[C@@H]2C[C@H](OCc3ccccc3)C2)cc1>>Cc1ccc(S(=O)(=O)O[C@@H]2C[C@H](O)C2)cc1 -US07468457B2,2,CC(C)(C)c1cc(C(=O)O)cc(I)c1O.CO>>COC(=O)c1cc(I)c(O)c(C(C)(C)C)c1 -US20110034526A1,1,CS(=O)(=O)c1ccc(F)cc1.Cc1cc(O)ccc1-n1c(C)nc2c(C(F)(F)F)cccc21>>Cc1cc(Oc2ccc(S(C)(=O)=O)cc2)ccc1-n1c(C)nc2c(C(F)(F)F)cccc21 -US20150225397A1,5,C[C@@H]1C(=O)CC[C@]2(c3ccc(O)cc3)[C@@H](O)CCC[C@@H]12.OCCO>>C[C@H]1[C@@H]2CCC[C@H](O)[C@@]2(c2ccc(O)cc2)CCC12OCCO2 -US20090100749A1,8,CCCCC(CC)CO>>CCCCC(C=O)CC -US20110263591A1,2,CN1CCNCC1.O=C(O)c1cccc(-c2cccc3cc(C(=O)N[C@@H]4CN5CCC4CC5)oc23)c1>>CN1CCN(C(=O)c2cccc(-c3cccc4cc(C(=O)N[C@@H]5CN6CCC5CC6)oc34)c2)CC1 -US20090286768A1,6,COc1cc(Oc2ccccc2)ccc1Br>>Oc1cc(Oc2ccccc2)ccc1Br -US20120329827A1,2,COC(=O)c1ncc(Cc2ccc(F)cc2)c(C)c1O.NO>>Cc1c(Cc2ccc(F)cc2)cnc(C(=O)NO)c1O -US20090186870A1,3,COC(=O)c1cc(B(O)O)ccc1Cl.O=[N+]([O-])c1cccnc1Br>>COC(=O)c1cc(-c2ncccc2[N+](=O)[O-])ccc1Cl -US08673940B2,1,Nc1nccs1.O=Cc1cnc(Br)s1>>Brc1ncc(CNc2nccs2)s1 -US07576109B2,1,CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCl.COC(=O)CCc1cccc(O)c1>>CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1cccc(CCC(=O)OC)c1 -US08455477B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1CNC1>>CC(C)(C)OC(=O)N1CC(C(=O)O)C1 -US07244725B2,3,CC(C)(C)C[Zn]Br.O=C1CCN(C(=O)OCc2ccccc2)c2ccc(Br)cc21>>CC(C)(C)Cc1ccc2c(c1)C(=O)CCN2C(=O)OCc1ccccc1 -US08998400B2,2,O=C(Cl)c1ccc2ccccc2c1.OCCO>>O=C(OCCO)c1ccc2ccccc2c1 -US20120271046A1,2,CC(C)(Br)C(=O)Br.NCc1ccccc1>>CC(C)(Br)C(=O)NCc1ccccc1 -US07732463B2,1,Fc1ccc(I)c(Br)c1.Fc1ccc(S)c(F)c1>>Fc1ccc(Sc2ccc(F)cc2Br)c(F)c1 -US04954518,6,CC(=O)NCc1coc2cc(NS(C)(=O)=O)c(Oc3ccccc3)cc2c1=O>>CS(=O)(=O)Nc1cc2occ(CN)c(=O)c2cc1Oc1ccccc1 -US20150057260A1,3,C#C[C@]1(O)CCN(C)C1=O.CCOC(=O)c1nc(-c2cccc(Br)c2)nc2ccc(OC)cc12>>CCOC(=O)c1nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)nc2ccc(OC)cc12 -US20090042929A1,1,CI.Cc1csc(CNC(=O)C23CC4CC(CC(C4)C2)C3)c1>>Cc1csc(CN(C)C(=O)C23CC4CC(CC(C4)C2)C3)c1 -US20120108577A1,1,COc1ccc2c(=O)ccn(CCN3CCC(N)CC3)c2c1.O=Cc1cc2c(cn1)OCCO2>>COc1ccc2c(=O)ccn(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c2c1 -US20100016319A1,1,CC(C)(C)[Si](C)(C)OCCBr.Oc1cccc(I)c1>>CC(C)(C)[Si](C)(C)OCCOc1cccc(I)c1 -US20150018363A1,1,CCc1nc2ccc(-n3ccc(O)cc3=O)cc2n1C.OCc1ccc(C(F)(F)F)s1>>CCc1nc2ccc(-n3ccc(OCc4ccc(C(F)(F)F)s4)cc3=O)cc2n1C -US05457115,2,O=C=NCCOCc1ccccc1.OCCNCCO>>O=C(NCCOCc1ccccc1)N(CCO)CCO -US20080027050A1,10,CCOC(=O)c1nc2cccc(C)c2c(=O)n1COCC[Si](C)(C)C.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc2cccc(CBr)c2c(=O)n1COCC[Si](C)(C)C -US20100130496A1,2,Nc1ccc2c(c1)CNCC2.O=C(Cl)OCc1ccccc1>>Nc1ccc2c(c1)CN(C(=O)OCc1ccccc1)CC2 -US05602118,2,O=C(Cl)OCc1ccc([N+](=O)[O-])cc1.O=[N+]([O-])c1ccc(O)cc1>>O=C(OCc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.O=C(Cl)c1cc(F)c(F)c(F)c1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)c4cc(F)c(F)c(F)c4)nc3cc21 -US20140142074A1,6,COc1ccc(C(=O)OCC(=O)OCc2ccccc2)cc1N(CC(N)=O)S(C)(=O)=O>>COc1ccc(C(=O)OCC(=O)O)cc1N(CC(N)=O)S(C)(=O)=O -US05192803,2,CCOC(=O)NCCO.CS(=O)(=O)Cl>>CCOC(=O)NCCOS(C)(=O)=O -US20120046267A1,1,CCI.Nc1ncc(I)c2cc(Cl)oc12>>CCNc1ncc(I)c2cc(Cl)oc12 -US20150250767A1,1,CC(C)(C)S(N)=O.COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C(=O)C(F)(F)F>>COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C(=NS(=O)C(C)(C)C)C(F)(F)F -US07618961B2,1,Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCOS(C)(=O)=O)cs1.c1c[nH]cn1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCn2ccnc2)cs1 -US20100197950A1,6,COC(=O)COc1ccc(OC(C)=O)cc1C>>COC(=O)COc1ccc(O)cc1C -US05173503,2,O=S(=O)(Cl)c1c[nH]cn1.c1ccc2c(c1)CCNC2>>O=S(=O)(c1c[nH]cn1)N1CCc2ccccc2C1 -US20090062253A1,1,CC(C)(C)c1ccc(C(=O)c2cncn2CCCN)cc1>>CC(C)(C)c1ccc(C2=NCCCn3cncc32)cc1 -US20060217348A1,1,COc1cc(C)cc(C)c1-c1cccc2c(NCC3CC3)c(OC)nn12.O=CC1CCOCC1>>COc1cc(C)cc(C)c1-c1cccc2c(N(CC3CCOCC3)CC3CC3)c(OC)nn12 -US20120107307A1,7,Cc1cc(NS(=O)(=O)C2(CC=O)CC2)c(N(C(=O)OC(C)(C)C)c2ccc(I)cc2F)n(C)c1=O>>Cc1cc(NS(=O)(=O)C2(CCO)CC2)c(N(C(=O)OC(C)(C)C)c2ccc(I)cc2F)n(C)c1=O -US07884114B2,6,CCCCc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c2ncccc2c1>>CCCCc1cc(OC2CCNCC2)c2ncccc2c1 -US20100016340A1,1,CC(C)(C)c1ccc(CC2(N)CCNCC2)cc1.Clc1ncnc2[nH]ncc12>>CC(C)(C)c1ccc(CC2(N)CCN(c3ncnc4[nH]ncc34)CC2)cc1 -US07279470B2,2,COc1ccc(CN2CCNCC2)cc1.O=C(CC1CCCCC1)Nc1ccc(OC(=O)Cl)cc1>>COc1ccc(CN2CCN(C(=O)Oc3ccc(NC(=O)CC4CCCCC4)cc3)CC2)cc1 -US20060052596A1,1,CI.COc1cc(OC)cc(C(=O)c2ccc3cc[nH]c3c2)c1>>COc1cc(OC)cc(C(=O)c2ccc3ccn(C)c3c2)c1 -US08088936B2,1,CCOC(=O)CCCOc1cccc(CCCCCCBr)c1CCC(=O)OCC.OCc1cc(O)cc(Br)c1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(CO)c2)c1CCC(=O)OCC -US07411093B2,1,CCOC(=O)[C@@H]1CCCC[C@@H]1NC(=O)CC(C)CCl>>CCOC(=O)[C@@H]1CCCC[C@H]1N1CC(C)CC1=O -US20140057895A1,1,N#CBr.c1cnc2[nH]ccc2c1>>N#Cn1ccc2cccnc21 -US20140113922A1,3,C=CC(=O)OC.Cc1ncc(Br)cn1>>COC(=O)C=Cc1cnc(C)nc1 -US20100130737A1,3,Clc1cc(I)ccn1.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2ccnc(Cl)c2)cc1 -US20100331326A1,1,Brc1ccsc1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccsc2)C1=O -US20100298325A1,6,CC(=O)Nc1cccc(Oc2cnc(Cl)c(F)c2)c1>>Nc1cccc(Oc2cnc(Cl)c(F)c2)c1 -US20140357858A1,2,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=C=Nc1ccccc1Cl>>O=C1CC(=O)N(c2ccc(NC(=O)Nc3ccccc3Cl)cc2)c2ccc3ccccc3c2N1 -US20130231306A1,1,CC(=O)N1CCNCC1.CN1Cc2c(C3CCC(=O)CC3)ccc(N)c2C1=O>>CC(=O)N1CCN(C2CCC(c3ccc(N)c4c3CN(C)C4=O)CC2)CC1 -US05318966,7,COc1cccc2c1CCC1=C2CC(=O)N1>>COc1cccc2c1CC[C@@H]1NC(=O)C[C@H]21 -US20110130398A1,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12.COC(=O)CCc1ccc(N)cc1>>COC(=O)CCc1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1 -US20060205794A1,6,O=S(=O)(c1cccc(CCCCOCCCCCCNC[C@H](O)c2ccc(OCc3ccccc3)c(F)c2)c1)C1CCCC1>>O=S(=O)(c1cccc(CCCCOCCCCCCNC[C@H](O)c2ccc(O)c(F)c2)c1)C1CCCC1 -US20100331315A1,1,Clc1cncc(Cl)n1.NCc1ccccc1Cl>>Clc1cncc(NCc2ccccc2Cl)n1 -US05556861,1,CC1(N)CNC1.COn1cc(C(=O)O)c(=O)c2cc3cc(F)c(F)cc3nc21>>COn1cc(C(=O)O)c(=O)c2cc3cc(F)c(N4CC(C)(N)C4)cc3nc21 -US05328922,2,Cn1ccc2cc(N)ccc21.O=C(Cl)Oc1ccccc1>>Cn1ccc2cc(NC(=O)Oc3ccccc3)ccc21 -US20140018371A1,7,CC(C)(C)OC(=O)N1CCC(COC2CC=C(c3ccc(S(C)(=O)=O)cc3)CC2)CC1>>CC(C)(C)OC(=O)N1CCC(COC2CCC(c3ccc(S(C)(=O)=O)cc3)CC2)CC1 -US20090042896A1,1,CC(O)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1.N#Cc1ccc(O)nc1>>CC(Oc1ccc(C#N)cn1)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1 -US20110257151A1,6,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(NC(=O)Cc3ccccc3)c1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(NC(=O)Cc2ccccc2)c1 -US20140364436A1,3,C#Cc1ccc(NC2CCC2)nn1.Cc1cn(-c2ccc(NC(=O)c3ccc(Cl)c(I)c3)cc2C(F)(F)F)cn1>>Cc1cn(-c2ccc(NC(=O)c3ccc(Cl)c(C#Cc4ccc(NC5CCC5)nn4)c3)cc2C(F)(F)F)cn1 -US20110207747A1,3,CC1(C)OB(c2cccnc2)OC1(C)C.COc1ccc(CNC(=O)c2cc(Br)ccc2I)cc1OC>>COc1ccc(CNC(=O)c2cc(Br)ccc2-c2cccnc2)cc1OC -US20150044776A1,6,CC(C)(C)OC(=O)NCCOCCOCCOCCOCCC(=O)NCc1cccc(C(=O)NCCOCCOCCCCCCCl)c1>>NCCOCCOCCOCCOCCC(=O)NCc1cccc(C(=O)NCCOCCOCCCCCCCl)c1 -US20080064720A1,6,COC(=O)C(Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)NC(=O)c1c(Cl)cccc1Cl>>O=C(NC(Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)C(=O)O)c1c(Cl)cccc1Cl -US20040235867A1,1,CN(C)C(=O)Cn1ccc2c(N)nccc21.N#Cc1cnc(Cl)s1>>CN(C)C(=O)Cn1ccc2c(Nc3ncc(C#N)s3)nccc21 -US08759528B2,1,CCNC(=O)C(C)c1ccc(C2CCNCC2)cc1.COc1cc(OCC2CC2)ccc1Br>>CCNC(=O)C(C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3OC)CC2)cc1 -US20140288041A1,3,COCCN(c1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1.OB(O)c1ccc(CN2CCOCC2)cc1>>COCCN(c1cc(-c2ccc(CN3CCOCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 -US20080214529A1,1,CC(C)CC=O.COC(=O)C1CCCN1N>>COC(=O)C1CCCN1N=CCC(C)C -US05919936,2,CN1CCC(c2c[nH]c3ccc(N)nc23)CC1.O=C(Cl)c1ccc(Cl)cc1Cl>>CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccc(Cl)cc4Cl)nc23)CC1 -US06441017B1,2,CC(C)[Si](OC(=O)N(CCc1cncn1Cc1ccc(C#N)c(F)c1)[C@H]1CCNC1)(C(C)C)C(C)C.CC(C)[Si](Oc1ccc2cccc(C(=O)O)c2c1)(C(C)C)C(C)C>>CC(C)[Si](OC(=O)N(CCc1cncn1Cc1ccc(C#N)c(F)c1)[C@H]1CCN(C(=O)c2cccc3ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc23)C1)(C(C)C)C(C)C -US20040138248A1,3,C#CCOCCn1c(CCOC)nc2cnc3ccccc3c21.Ic1ccccc1>>COCCc1nc2cnc3ccccc3c2n1CCOCC#Cc1ccccc1 -US20150191439A1,1,NC12CC3CC(CC(C3)C1)C2.O=Cc1cc2cccnc2s1>>c1cnc2sc(CNC34CC5CC(CC(C5)C3)C4)cc2c1 -US20150252008A1,1,CS(=O)(=O)NCCCl.Nc1cnc(-c2ccc(C3CCC3)c(O)c2F)cn1>>CS(=O)(=O)NCCOc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F -US08067408B2,1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(-c3cccc(C=O)c3)c2)c1.C[C@H]1CNC[C@@H](C)N1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(-c3cccc(CN4C[C@H](C)N[C@H](C)C4)c3)c2)c1 -US06194410B1,9,CCc1nn2c(Cl)c3c(nc2c1S(=O)(=O)c1ccccc1)CCC3.N>>CCc1nn2c(N)c3c(nc2c1S(=O)(=O)c1ccccc1)CCC3 -US20150183824A1,6,CCC[C@H](NC(=O)OC(C)(C)C)C(OCC)(OCC)C(=O)OCC>>CCC[C@H](NC(=O)OC(C)(C)C)C(OCC)(OCC)C(=O)O -US20120270865A2,2,CCOC(=O)CCNC.Cc1c(C(CC(C)C)Nc2ccc(C(=O)O)cc2)oc2ccc(Cl)cc12>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(CC(C)C)c2oc3ccc(Cl)cc3c2C)cc1 -US20120129811A1,2,Cn1cnc2c(N=C=S)cccc21.Nc1cccnc1>>Cn1cnc2c(NC(=S)Nc3cccnc3)cccc21 -US06046227,7,CC(C)(CCc1ccc(O)cc1)NC(=O)c1ccccc1>>CC(C)(CCc1ccc(O)cc1)NCc1ccccc1 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.N#Cc1cccc(O)c1>>CC#CCOc1cc(Oc2cccc(C#N)c2)ncn1 -US20040106653A1,1,CCOC(=O)Cc1cc(S(=O)(=O)c2ccc(CCN)cc2)ccc1O.O=Cc1ccccc1>>CCOC(=O)Cc1cc(S(=O)(=O)c2ccc(CCNCc3ccccc3)cc2)ccc1O -US20090312327A1,6,CCN(C(=O)OC(C)(C)C)[C@@H]1CN(C(=O)N2CCN(S(C)(=O)=O)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1>>CCN[C@@H]1CN(C(=O)N2CCN(S(C)(=O)=O)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US05493030,6,COCCOCOc1c(C/C=C(\C)CCC(=O)OC)c(OC)c(C)c2c1C(=O)OC2>>COCCOCOc1c(CC=C(C)CCC(=O)O)c(OC)c(C)c2c1C(=O)OC2 -US20150258204A1,9,COC(=O)CCCCCBr.[N-]=[N+]=[N-]>>COC(=O)CCCCCN=[N+]=[N-] -US20100041892A1,7,CCOC(=O)CCc1ccc(OCCOC)cc1OCC1CC1>>COCCOc1ccc(CCCO)c(OCC2CC2)c1 -US08003662B2,2,CN1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(N)cc5F)c4s3)o2)CC1.O=C(Cc1ccccc1)N=C=S>>CN1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=S)NC(=O)Cc6ccccc6)cc5F)c4s3)o2)CC1 -US20100168175A1,6,CCCCCC(C)C(=O)c1c(O)c(OC)c(OC)n(Cc2ccc(OC)cc2)c1=O>>CCCCCC(C)C(=O)c1c(O)c(OC)c(OC)[nH]c1=O -US20110288067A1,2,CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Oc3ccc4c(c3)[C@H](N)CC4)nc12.CS(=O)(=O)Cl>>CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Oc3ccc4c(c3)[C@H](NS(C)(=O)=O)CC4)nc12 -US20110178132A1,3,Cc1ccccc1B(O)O.N#Cc1cc(Cl)ccn1>>Cc1ccccc1-c1ccnc(C#N)c1 -US05403852,4,N#CCCCCCCc1nc(-c2ccccc2)c(-c2ccccc2)o1.[N-]=[N+]=[N-]>>c1ccc(-c2nc(CCCCCCc3nnn[nH]3)oc2-c2ccccc2)cc1 -US20060293343A1,9,CCc1c(C)nc(-c2cccs2)nc1Nc1ccc(CC(=O)O)cc1.N>>CCc1c(C)nc(-c2cccs2)nc1Nc1ccc(CC(N)=O)cc1 -US20150284358A1,6,COC(=O)c1c(C(C)(C)O)nc(-c2cccnc2)n1Cc1cc(Cl)ccc1Cl>>CC(C)(O)c1nc(-c2cccnc2)n(Cc2cc(Cl)ccc2Cl)c1C(=O)O -US07786129B2,1,CCC1(CCCCCl)C(=O)Nc2ccccc21.Fc1ccc(N2CCNCC2)cc1Cl>>CCC1(CCCCN2CCN(c3ccc(F)c(Cl)c3)CC2)C(=O)Nc2ccccc21 -US20080039459A1,3,CC(CC(=O)Nc1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1)NC(=O)OC(C)(C)C.CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C>>CC(CC(=O)Nc1cccc(-c2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)c1)NC(=O)OC(C)(C)C -US20040106679A1,2,NCC(=O)CCC(=O)O.O=[N+]([O-])c1cccc(CO)c1>>NCC(=O)CCC(=O)OCc1cccc([N+](=O)[O-])c1 -US20110046134A1,6,O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1ccc(-c2ccccc2OCc2ccccc2)cc1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1ccc(-c2ccccc2O)cc1 -US20060205673A1,2,CN(C)c1ccc(CN[C@@H](C(=O)O)[C@H](O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1.COc1ccc(CNC(=O)[C@@H](N)C(C)C)c(O)c1>>COc1ccc(CNC(=O)[C@@H](NC(=O)[C@H](NCc2ccc(N(C)C)cc2)[C@H](O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)C(C)C)c(O)c1 -US04931436,2,C1CCN(CCC2CNCCO2)CC1.O=C1Nc2ccccc2N(C(=O)Cl)c2ncccc21>>O=C1Nc2ccccc2N(C(=O)N2CCOC(CCN3CCCCC3)C2)c2ncccc21 -US20090215759A1,1,Cc1cc(Cl)nc(Cl)n1.Oc1ccc(F)cc1>>Cc1cc(Oc2ccc(F)cc2)nc(Cl)n1 -US06140349,9,CC(C)(C)OC(=O)N1CCC(N=[N+]=[N-])CC1>>CC(C)(C)OC(=O)N1CCC(N)CC1 -US08921397B2,2,CC(C)(C)c1ccc(C(=O)O)cc1.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CC(C)(C)c1ccc(C(=O)N[C@@H]2CC[C@@H](CCN3CCCCC3c3coc4cccc-4c3)CC2)cc1 -US20070213331A1,6,CCC[S@](=O)c1cc(C(=O)OC)cc(NC(C)CC)n1>>CCC[S@](=O)c1cc(C(=O)O)cc(NC(C)CC)n1 -US07001897B2,2,CS(=O)(=O)Cl.O=C(OCc1ccc([N+](=O)[O-])cc1)c1csc(N2CCC(O)CC2)n1>>CS(=O)(=O)OC1CCN(c2nc(C(=O)OCc3ccc([N+](=O)[O-])cc3)cs2)CC1 -US20070021414A1,7,COCc1ccc(C2(O)CCN(CC(=O)c3ccc(OCc4ccccc4)c(Cl)c3)CC2)cc1>>COCc1ccc(C2(O)CCN(CC(O)c3ccc(OCc4ccccc4)c(Cl)c3)CC2)cc1 -US09131693B2,1,CC(=O)CCl.Oc1ccc(F)cc1Cl>>CC(=O)COc1ccc(F)cc1Cl -US05753679,6,CCOC(=O)C1CCN(Cc2ccccc2)CC1>>O=C(O)C1CCN(Cc2ccccc2)CC1 -US20090286790A1,1,CCC1CC(N)CC(CC)N1C(=O)OC(C)C.Clc1ncc(Br)cn1>>CCC1CC(Nc2ncc(Br)cn2)CC(CC)N1C(=O)OC(C)C -US20100227887A1,2,CCOC(=O)c1cc(Br)cc(CC)n1.Nc1ccc(F)cn1>>CCc1cc(Br)cc(C(=O)Nc2ccc(F)cn2)n1 -US20110092526A1,1,CCOc1nc(Cl)ncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2.N[C@H]1CCOC1>>CCOc1nc(N[C@H]2CCOC2)ncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 -US08765730B2,9,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(C(=O)NCCO)cc1.NO>>Cc1cc(Cl)ccc1C(C/C(=N\O)c1ccc(=O)n(C)c1)c1ccc(C(=O)NCCO)cc1 -US20060089394A1,1,CCCCC(O)c1cccc(Br)c1.CCOC(=O)COc1ccc(O)cc1C>>CCCCC(Oc1ccc(OCC(=O)OCC)c(C)c1)c1cccc(Br)c1 -US20090029976A1,6,CCOC(=O)c1oc2cc(OC)ccc2c1C(C)C>>CCOC(=O)c1oc2cc(O)ccc2c1C(C)C -US20100016401A1,2,O=C(NC[C@H]1NC[C@H]2C[C@H]21)c1cccc2occc12.O=C(O)c1nccnc1-c1ccccc1>>O=C(NC[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)c1nccnc1-c1ccccc1)c1cccc2occc12 -US06407094B1,1,C=CCO.Nc1cc(Cl)c(I)cc1[N+](=O)[O-]>>C=CCOc1cc(N)c([N+](=O)[O-])cc1I -US20130289029A1,1,C=O.CC(C)(C)OC(=O)N[C@H]1CCNC1>>CN1CC[C@H](NC(=O)OC(C)(C)C)C1 -US06355680B1,1,CCCCOc1ccc(N)cc1.O=C(O)Cc1ccccc1Br>>CCCCOc1ccc(Nc2ccccc2CC(=O)O)cc1 -US08399436B2,1,Cc1cc([N+](=O)[O-])ccc1CBr.O=C(Nc1cc[nH]n1)c1c(F)cccc1F>>Cc1cc([N+](=O)[O-])ccc1Cn1ccc(NC(=O)c2c(F)cccc2F)n1 -US20090286768A1,6,Nc1ncnn2c([C@@H]3CC[C@@H](CNC(=O)OCc4ccccc4)CC3)nc(-c3ccc(Oc4ccccc4)cc3)c12>>NC[C@@H]1CC[C@@H](c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnn23)CC1 -US08975254B2,2,NCCc1ccc(-c2ccc(Cl)c(Cl)c2)o1.O=C(O)c1cc2ncccn2n1>>O=C(NCCc1ccc(-c2ccc(Cl)c(Cl)c2)o1)c1cc2ncccn2n1 -US08846661B2,3,Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1.OB(O)c1ccc2c(c1)OCCO2>>c1cc2c(cc1-c1cncc(N3CC4CC5CC3CN(C5)C4)c1)OCCO2 -US08426411B2,1,Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc(C[C@@H]4CCNC4)n23)cc1.N#Cc1cnc(Cl)cn1>>Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc(C[C@@H]4CCN(c5cnc(C#N)cn5)C4)n23)cc1 -US06194406B1,2,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.COc1ccc(CS(C)(=O)=O)cc1C(=O)O>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(CS(C)(=O)=O)ccc4OC)C3)CC2)nc2ccccc21 -US20110166169A1,1,CC(C)(C)OC(=O)c1ccc(-n2c3ccccc3c3c(-c4ccc(C#N)nc4)cccc32)cc1F.NCCF>>CC(C)(C)OC(=O)c1ccc(-n2c3ccccc3c3c(-c4ccc(C#N)nc4)cccc32)cc1NCCF -US20130225524A1,3,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(Cl)ccc23)c1.Cc1ncccc1B(O)O>>CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4cccnc4C)ccc23)c1 -US06969725B2,6,CCO[C@@H](Cc1ccc(OCc2nc(-c3ccc(OC(C)C)cc3)oc2C)cc1C)C(=O)OC>>CCO[C@@H](Cc1ccc(OCc2nc(-c3ccc(OC(C)C)cc3)oc2C)cc1C)C(=O)O -US06720346B2,2,CN(C)C1(CN)CCCC1.Nc1nc(Nc2ccc(C(=O)O)cc2)sc1C(=O)c1c(F)cccc1F>>CN(C)C1(CNC(=O)c2ccc(Nc3nc(N)c(C(=O)c4c(F)cccc4F)s3)cc2)CCCC1 -US20150005304A1,6,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)C=CO2>>O=C1C=COC2(CCNCC2)C1 -US08173682B2,2,CCC(N)c1ccc(C)nc1.CCc1cc(-c2cncc(C(=O)O)c2)c(C)[nH]c1=O>>CCc1cc(-c2cncc(C(=O)NC(CC)c3ccc(C)nc3)c2)c(C)[nH]c1=O -US20060223801A1,1,Cc1[nH]c(C(=O)O)cc1Br.NC(=O)c1cc(Cl)nc(N2CCC(O)CC2)c1>>Cc1[nH]c(C(=O)OC2CCN(c3cc(C(N)=O)cc(Cl)n3)CC2)cc1Br -US20090137603A1,2,Nc1nc[nH]n1.O=C(O)CCCOc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1>>O=C(CCCOc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1)Nc1nc[nH]n1 -US20140113877A1,6,COc1cc(F)ccc1-c1cc2c(s1)c(=O)n(C1CCN(C(=O)OC(C)(C)C)CC1)c(=O)n2Cc1ccc(OC)c(F)c1F>>COc1cc(F)ccc1-c1cc2c(s1)c(=O)n(C1CCNCC1)c(=O)n2Cc1ccc(OC)c(F)c1F -US20070105836A1,2,CCCCCCCCCCCCCCCCOC(=O)Cl.Clc1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1N2>>CCCCCCCCCCCCCCCCOC(=O)N1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 -US07504522B2,3,FC(F)(F)c1ccccc1[Mg+].O=Cc1ccc(Br)cc1F>>OC(c1ccc(Br)cc1F)c1ccccc1C(F)(F)F -US06960688B2,8,C[C@@](O)(C(=O)Nc1ccc(Sc2ccc(C(=O)O)cc2)cc1Cl)C(F)(F)F.O=S([O-])OO>>C[C@@](O)(C(=O)Nc1ccc(S(=O)c2ccc(C(=O)O)cc2)cc1Cl)C(F)(F)F -US20150152118A1,1,CCOC(=O)C1=C(NC(=O)[C@H]2CCC(=O)C2)CCC2(CC2)C1.Fc1ccc(N2CCNCC2)cc1>>CCOC(=O)C1=C(NC(=O)[C@H]2CC[C@@H](N3CCN(c4ccc(F)cc4)CC3)C2)CCC2(CC2)C1 -US08796256B2,1,COCCBr.O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1N1CCNCC1>>COCCN1CCN(N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)CC1 -US08461134B2,2,NCc1ccccc1.Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CC(=O)O)c1>>Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CC(=O)NCc2ccccc2)c1 -US20080306082A1,6,COC(=O)c1cccc2sc(-c3nc(NCCCN4CCN(C)CC4)ncc3Cl)cc12>>CN1CCN(CCCNc2ncc(Cl)c(-c3cc4c(C(=O)O)cccc4s3)n2)CC1 -US20110319393A1,1,CC(C)(C)c1ccc(Br)cc1.COC(=O)CCCC1CCNCC1>>COC(=O)CCCC1CCN(c2ccc(C(C)(C)C)cc2)CC1 -US20150210685A1,7,O=C(O[C@@H]1CO[C@@H]2COC(c3ccccc3)O[C@H]2C1)c1ccccc1>>O[C@@H]1CO[C@@H]2COC(c3ccccc3)O[C@H]2C1 -US06610707B1,2,O=C(OCc1ccccc1)[C@@H]1CCCN1.O=S(=O)(Cl)c1ccc(F)cc1>>O=C(OCc1ccccc1)[C@@H]1CCCN1S(=O)(=O)c1ccc(F)cc1 -US20140364433A1,1,C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-n2nccn2)[C@@H]1CN.FC(F)(F)c1ccc(Cl)nn1>>C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-n2nccn2)[C@@H]1CNc1ccc(C(F)(F)F)nn1 -US04175203,1,C=[N+]=[N-].CCCCCC(O)CCCC(CCCc1ccc(C(=O)O)cc1)C(C)=O>>CCCCCC(O)CCCC(CCCc1ccc(C(=O)OC)cc1)C(C)=O -US05244889,6,CC(=O)SC[C@H]1CCCCCC[C@H](C(=O)Nc2cccnc2)NC1=O>>O=C(Nc1cccnc1)[C@H]1CCCCCC[C@H](CS)C(=O)N1 -US20070155716A1,2,CN.O=C(O)c1cnccc1Nc1nc(-c2cc(Cl)ccc2F)nc2c1OCC2>>CNC(=O)c1cnccc1Nc1nc(-c2cc(Cl)ccc2F)nc2c1OCC2 -US20070043072A1,6,CC(=O)Nc1cc(C)cc(/C=C/c2nc3cc(Br)cnc3[nH]2)n1>>Cc1cc(N)nc(/C=C/c2nc3cc(Br)cnc3[nH]2)c1 -US20090298878A1,1,CCO.O=S(=O)(c1ccc(F)cc1)N1CCC(=NOCc2cccc(C(F)(F)F)c2)CC1>>CCOc1ccc(S(=O)(=O)N2CCC(=NOCc3cccc(C(F)(F)F)c3)CC2)cc1 -US06630461B2,7,O=[N+]([O-])c1ccc(-n2ccnc2)cc1>>Nc1ccc(-n2ccnc2)cc1 -US20080188528A1,6,COC(=O)CC[C@H](NC(=O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O -US20030134854A1,1,C1CSCCN1.COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccnc(Br)c3)nc12>>COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccnc(N4CCSCC4)c3)nc12 -US06329405B1,7,COc1ccc(C(NC(C)c2ccc(F)c(F)c2)c2cccc(C#N)c2)cc1>>COc1ccc(C(NC(C)c2ccc(F)c(F)c2)c2cccc(CN)c2)cc1 -US08580962B2,6,CC(C)(C)OC(=O)N1CCC2(CC1)CC(C#Cc1ccccc1)=NO2>>C(#Cc1ccccc1)C1=NOC2(CCNCC2)C1 -US20100120785A1,3,Cc1nn(C)cc1CN1CCN(c2nccnc2Cl)CC1.OB(O)c1ccc(Cl)cc1>>Cc1nn(C)cc1CN1CCN(c2nccnc2-c2ccc(Cl)cc2)CC1 -US20030144333A1,6,CCOC(=O)C(=O)c1cc(Br)c(Br)s1>>O=C(O)C(=O)c1cc(Br)c(Br)s1 -US07279470B2,2,CN(C(=O)Cl)c1ccccc1.Oc1cccnc1>>CN(C(=O)Oc1cccnc1)c1ccccc1 -US20100298287A1,1,CCC(CC)c1ccc(Cl)c2nc(Cl)n(CC(=O)OC(C)C)c12.Nc1ccc(Cl)cc1Cl>>CCC(CC)c1ccc(Cl)c2nc(Nc3ccc(Cl)cc3Cl)n(CC(=O)OC(C)C)c12 -US20100041714A1,3,CC(C)(C)OC(=O)COc1cccc2c1CCCC2NS(=O)(=O)c1ccc(Br)cc1.OB(O)c1cc(F)ccn1>>CC(C)(C)OC(=O)COc1cccc2c1CCCC2NS(=O)(=O)c1ccc(-c2cc(F)ccn2)cc1 -US08063099B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c1.O=C(O)c1nccc2ccccc12>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2nccc3ccccc23)c1 -US06201013B1,1,CN1CCC(O)C1.O=[N+]([O-])c1ccc(O)c(Cl)c1>>CN1CCC(Oc2ccc([N+](=O)[O-])cc2Cl)C1 -US20110009454A1,2,COc1ccc(Oc2cccc(CN)c2)cc1.Cc1ccc(C(=O)O)c(N)n1>>COc1ccc(Oc2cccc(CNC(=O)c3ccc(C)nc3N)c2)cc1 -US20120149677A1,6,COc1ccc2c(nnn2CC2CC2)c1Cl>>Oc1ccc2c(nnn2CC2CC2)c1Cl -US20110034469A1,6,C[C@@H](C(=O)N[C@H](C(=O)N1C[C@H]2CC(F)(F)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1)N(C)C(=O)OC(C)(C)C>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CC(F)(F)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCCCC1 -US20050113419A1,2,CCCc1c(OCCCNCC)ccc2c(C(F)(F)F)noc12.CN=C=O>>CCCc1c(OCCCN(CC)C(=O)NC)ccc2c(C(F)(F)F)noc12 -US20130217759A1,2,CCOC(=O)c1c(N)sc(Br)c1C.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)c1c(NS(=O)(=O)c2ccccc2)sc(Br)c1C -US20080070912A1,7,CC(C)C(=O)c1c(C(C)C)nn2ccccc12>>CC(C)c1nn2ccccc2c1C(O)C(C)C -US06043210,2,O=C(O)CCCCCSCCCCCCCCO>>O=C1CCCCCSCCCCCCCCO1 -US20090270625A1,2,CCC[C@H]1Nc2ccccc2[C@H]2[C@@H]1CCN2C(=O)[C@H]1CCCC[C@H]1N.Cc1nc2cc(C(=O)O)ccc2[nH]1>>CCC[C@@H]1Nc2ccccc2[C@H]2[C@@H]1CCN2C(=O)[C@H]1CCCC[C@H]1NC(=O)c1ccc2[nH]c(C)nc2c1 -US20120028937A1,6,COc1cc(CNC(=O)C2CNC2)ccc1OCc1ccccc1>>COc1cc(CNC(=O)C2CNC2)ccc1O -US04085116,1,CC(=O)[O-].CC(Br)c1ccc2occ(C#N)c(=O)c2c1>>CC(=O)OC(C)c1ccc2occ(C#N)c(=O)c2c1 -US08431576B2,2,O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1CO.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)OCN1C(=O)CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc21 -US08546603B2,7,CCOC(=O)CCCC(C)=O>>CCOC(=O)CCC[C@@H](C)O -US07973078B2,6,Cc1ccc(S(=O)(=O)N(CC(=O)NCc2ccc(OCc3ccccc3)cc2)c2cccc(Cl)c2C)cc1>>Cc1ccc(S(=O)(=O)N(CC(=O)NCc2ccc(O)cc2)c2cccc(Cl)c2C)cc1 -US20100075952A1,3,CCNCCN1CCCc2[nH]c(C=O)c(C)c2C1=O.O=C1Cc2cc(F)ccc2N1>>CCNCCN1CCCc2[nH]c(C=C3C(=O)Nc4ccc(F)cc43)c(C)c2C1=O -US20120029190A1,9,N#Cc1cc(F)cc(C2CCC(=O)C(Br)C2)c1.[N-]=[N+]=[N-]>>N#Cc1cc(F)cc(C2CCC(=O)C(N=[N+]=[N-])C2)c1 -US20140336415A1,1,COc1ccc(N)cc1.O=[N+]([O-])c1c(Cl)cccc1Cl>>COc1ccc(Nc2cccc(Cl)c2[N+](=O)[O-])cc1 -US07943609B2,1,COc1ccc(CN)cc1.Cc1nc(Cl)c2nc3n(c2c1C)[C@@H](C)COC3>>COc1ccc(CNc2nc(C)c(C)c3c2nc2n3[C@@H](C)COC2)cc1 -US20050014807A1,2,CCCc1c(OCCCC(=O)O)ccc2c(CC(C)(C)C)noc12.NCc1ccco1>>CCCc1c(OCCCC(=O)NCc2ccco2)ccc2c(CC(C)(C)C)noc12 -US20060122168A1,6,COC(=O)C(CC1OCCO1)C(=O)OC>>COC(=O)C(CC1OCCO1)C(=O)O -US20050014807A1,1,BrCCCBr.CCCc1c(O)ccc2c(CC(C)(C)C)noc12>>CCCc1c(OCCCBr)ccc2c(CC(C)(C)C)noc12 -US05883098,6,O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(Cc2ccccc2)C[C@H]1Cc1c[nH]c2ccccc12>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCNC[C@H]1Cc1c[nH]c2ccccc12 -US03984422,1,CCI.CCOC(=O)c1cnc(O)c2c(C)n[nH]c12>>CCOC(=O)c1cnc(OCC)c2c(C)n[nH]c12 -US08193378B2,5,COCCl.O=Cc1c(O)cc(O)cc1F>>COCOc1cc(O)c(C=O)c(F)c1 -US05064959,2,CCCCO.O=C(Cl)c1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1>>CCCCOC(=O)c1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1 -US20100210642A1,3,C#C[Si](C)(C)C.FC(F)(F)c1ccc(-c2cc(C(F)(F)F)n3cnc(I)c3n2)cc1>>C[Si](C)(C)C#Cc1ncn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12 -US06888032B2,9,Cc1ccc(C)c(Br)c1.[C-]#N>>Cc1ccc(C)c(C#N)c1 -US06369273B1,2,C[C@@](O)(C(=O)O)C(F)(F)F.Nc1ccc(S(=O)(=O)c2ccc(Br)cc2)cc1Cl>>C[C@@](O)(C(=O)Nc1ccc(S(=O)(=O)c2ccc(Br)cc2)cc1Cl)C(F)(F)F -US20080125409A1,6,COC(=O)c1nc(-c2ccc(OCc3ccccc3)cn2)n(-c2ccc(OC)nc2)n1>>COC(=O)c1nc(-c2ccc(O)cn2)n(-c2ccc(OC)nc2)n1 -US20050143372A1,2,CCNC1CCN(Cc2cccc(Oc3ccccc3OC)c2)CC1.O=C(Cl)Cc1ccccc1>>CCN(C(=O)Cc1ccccc1)C1CCN(Cc2cccc(Oc3ccccc3OC)c2)CC1 -US04846880,7,CC1=NC(C)Cc2ccccc21>>CC1Cc2ccccc2C(C)N1 -US20010014691A1,1,CCN.ClCCCOc1cccnc1>>CCNCCCOc1cccnc1 -US20020193560A1,6,CCCCCCOc1ccc(C2(O)CCN(C(=O)OCc3ccccc3)CC2)cc1>>CCCCCCOc1ccc(C2(O)CCNCC2)cc1 -US20060046978A1,6,COC(=O)C(CNC(=O)CCC(NC(=O)OC(C)(C)C)C(=O)N1CCCC1C#N)NC(=O)C(CSC(C)=O)Cc1ccccc1>>COC(=O)C(CNC(=O)CCC(N)C(=O)N1CCCC1C#N)NC(=O)C(CSC(C)=O)Cc1ccccc1 -US08173682B2,2,CCc1cc(-c2ccc(S(=O)(=O)Cl)s2)c(C)[nH]c1=O.Cc1ccc(CN)o1>>CCc1cc(-c2ccc(S(=O)(=O)NCc3ccc(C)o3)s2)c(C)[nH]c1=O -US20080153810A1,2,CN.CN(CC(=O)O)c1n[nH]c2ccc([N+](=O)[O-])cc12>>CNC(=O)CN(C)c1n[nH]c2ccc([N+](=O)[O-])cc12 -US20090226398A1,3,Fc1cccc(-c2nc3cnn(Cc4ccc(Br)cc4)cc-3n2)c1F.OB(O)c1ccc(C(F)(F)F)cc1C(F)(F)F>>Fc1cccc(-c2nc3cnn(Cc4ccc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)cc4)cc-3n2)c1F -US08148421B2,7,CC(C(=O)O)c1ccc(CC2CSCC2=O)cc1>>CC(C(=O)O)c1ccc(CC2CSCC2O)cc1 -US05151432,2,CCC[C@H](N[C@@H](C)C(=O)O)C(=O)OCC.NC(=O)[C@H]1NC2CCC1CC2>>CCC[C@H](N[C@@H](C)C(=O)N1C2CCC(CC2)[C@H]1C(N)=O)C(=O)OCC -US20100249123A1,2,COCCn1cc(C(=O)O)c2cc(F)ccc21.COc1ccc(C(=O)Nc2ccc(C(C)(C)CN)cc2)cc1OC>>COCCn1cc(C(=O)NCC(C)(C)c2ccc(NC(=O)c3ccc(OC)c(OC)c3)cc2)c2cc(F)ccc21 -US05597820,1,CCI.COC(=O)c1ccc2c(c1)OC(C)C(=O)N2>>CCN1C(=O)C(C)Oc2cc(C(=O)OC)ccc21 -US20060229330A1,2,CCS(=O)(=O)Cl.COc1ccc(F)cc1C(=O)c1cnc(NC2CCNCC2)nc1N>>CCS(=O)(=O)N1CCC(Nc2ncc(C(=O)c3cc(F)ccc3OC)c(N)n2)CC1 -US20070167447A1,1,CCCC[Sn](Cl)(CCCC)CCCC.COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(C(=O)OC(C)(C)C)c2c1>>CCCC[Sn](CCCC)(CCCC)c1c(C2CCCCC2)c2ccc(C(=O)OC)cc2n1C(=O)OC(C)(C)C -US20130281432A1,1,Cn1cc(Br)nc(Br)c1=O.Nc1cnn(C2CC2)c1>>Cn1cc(Br)nc(Nc2cnn(C3CC3)c2)c1=O -US20140004243A1,2,NCc1ccccc1.O=C(O)CCCc1ccccc1>>O=C(CCCc1ccccc1)NCc1ccccc1 -US20070203114A1,7,Cc1nc2c3c(c(C(=O)N(C)C)cn2c1C=O)CCC(c1ccccc1)C3>>Cc1nc2c3c(c(C(=O)N(C)C)cn2c1CO)CCC(c1ccccc1)C3 -US20130165483A1,9,Cn1c(Cl)cc(C(=O)O)c1Cl.N>>Cn1c(Cl)cc(C(N)=O)c1Cl -US06350749B1,3,CC(=O)O.O=C1CC(=O)CC(c2ccccc2Cl)C1>>CC(O)=C1C(=O)CC(c2ccccc2Cl)CC1=O -US08445480B2,7,COC(=O)c1cc(C#N)cc([N+](=O)[O-])c1O>>COC(=O)c1cc(C#N)cc(N)c1O -US04962224,10,COc1ccc2c(C)c(Br)ccc2c1C(F)(F)F.O=C1CCC(=O)N1Br>>COc1ccc2c(CBr)c(Br)ccc2c1C(F)(F)F -US05981533,1,COc1cc(C=O)ccc1O.Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12>>COc1cc(CNc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)ccc1O -US08309734B2,2,O=C(O)c1cccnc1Oc1cc(Cl)ccc1Cl.c1ccc2c(c1)NCCN2>>O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CCNc2ccccc21 -US20110021523A1,2,CS(=O)(=O)c1ccc(S(=O)(=O)Cl)cc1.Cc1ncccc1C(=O)c1cc(Cl)ccc1N>>Cc1ncccc1C(=O)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(S(C)(=O)=O)cc1 -US20150210688A1,6,COC(=O)c1ccc(C)c(-c2nc(C)[nH]c2Cl)c1>>Cc1nc(-c2cc(C(=O)O)ccc2C)c(Cl)[nH]1 -US05925635,2,N#Cc1cccc(N=C=O)c1.OCCNC1CCN(Cc2ccccc2)CC1>>N#Cc1cccc(NC(=O)N(CCO)C2CCN(Cc3ccccc3)CC2)c1 -US20130150372A1,1,NC1CC1.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1NC1CC1 -US07622605B2,6,CCOC(OCC)c1nc(C2CC2)n(C)n1>>Cn1nc(C=O)nc1C1CC1 -US20080200527A1,9,Cc1c(C(=O)NCCCC(N)=O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1>>Cc1c(C(=O)NCCCC#N)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 -US20070082912A1,1,Cc1ccc(O)c(C=O)c1.Fc1ccc(CBr)cc1>>Cc1ccc(OCc2ccc(F)cc2)c(C=O)c1 -US20100256134A1,2,CS(N)(=O)=O.Cc1cccc(C2CCN(C(=O)c3cnc4c(C(=O)O)cnn4c3NCc3ccccc3)CC2)c1>>Cc1cccc(C2CCN(C(=O)c3cnc4c(C(=O)NS(C)(=O)=O)cnn4c3NCc3ccccc3)CC2)c1 -US06156758,1,COC(=O)c1ccc(Cl)nc1.NC1CCN(Cc2ccccc2)CC1>>COC(=O)c1ccc(NC2CCN(Cc3ccccc3)CC2)nc1 -US05098919,2,CN.COC(=O)CC1CSC2=C(C(=O)OC(C)C)C(C)CN21>>CNC(=O)CC1CSC2=C(C(=O)OC(C)C)C(C)CN21 -US20070010526A1,6,CCCc1cc(N2CCN(C)CC2)c2c(c1OC)CCN(C(=O)OC(C)(C)C)C2>>CCCc1cc(N2CCN(C)CC2)c2c(c1OC)CCNC2 -US08324264B1,1,C1COCCN1.O=Cc1sccc1Br>>Brc1ccsc1CN1CCOCC1 -US20050054627A1,6,CCOC(=O)c1cccc(-c2cccc(NS(=O)(=O)C(F)(F)F)c2)c1>>O=C(O)c1cccc(-c2cccc(NS(=O)(=O)C(F)(F)F)c2)c1 -US20100267696A1,1,O=C(c1csc(Br)c1)N1CCC[C@@H]2CCCC[C@@H]21.O=C1CNCCN1>>O=C1CNCCN1c1cc(C(=O)N2CCC[C@@H]3CCCC[C@@H]32)cs1 -US08455488B2,2,CCNC(=O)NOCC(=O)O.CCOC(OCC)[C@H](C)N(Cc1cccc2ccccc12)C(=O)[C@@H](N)CCCCNC(=O)OC(C)(C)C>>CCNC(=O)NOCC(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)N(Cc1cccc2ccccc12)[C@@H](C)C(OCC)OCC -US04870083,7,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1 -US20140066369A1,2,CS(=O)(=O)Cl.OCC1CCC2(CC1)OCCO2>>CS(=O)(=O)OCC1CCC2(CC1)OCCO2 -US20150099893A1,7,C(=C1c2ccccc2Sc2ccccc21)c1ccccc1>>c1ccc(CC2c3ccccc3Sc3ccccc32)cc1 -US20080234199A1,6,CCC(=C(c1ccc(OC(C)=O)cc1)c1ccc(OC(C)=O)cc1)c1ccc(/C=C/C(=O)OC(C)(C)C)cc1>>CCC(=C(c1ccc(OC(C)=O)cc1)c1ccc(OC(C)=O)cc1)c1ccc(/C=C/C(=O)O)cc1 -US06160000,6,CCCc1c(OCCc2cc3cc(CC(=O)OC)ccc3[nH]2)ccc2c(-c3ccccc3)coc12>>CCCc1c(OCCc2cc3cc(CC(=O)O)ccc3[nH]2)ccc2c(-c3ccccc3)coc12 -US20040082611A1,6,CC(C)(C)OC(=O)CC1Cc2nc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)sc2CN1>>O=C(O)CC1Cc2nc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)sc2CN1 -US20110237517A1,6,CC(C)(C)OC(=O)N1CCC2C1C(c1c[nH]c3cc(F)ccc13)CN2S(C)(=O)=O>>CS(=O)(=O)N1CC(c2c[nH]c3cc(F)ccc23)C2NCCC21 -US08952058B2,1,CCOc1ccccc1N.COc1cc2ncn(Cc3ccc4nc(Br)sc4c3)c2cc1OC>>CCOc1ccccc1Nc1nc2ccc(Cn3cnc4cc(OC)c(OC)cc43)cc2s1 -US07705028B2,1,CC(C)c1onc(CCc2c(Cl)cccc2Cl)c1CO.COC(=O)c1ccc2ccc(-c3ccc(O)cc3)cc2c1>>COC(=O)c1ccc2ccc(-c3ccc(OCc4c(CCc5c(Cl)cccc5Cl)noc4C(C)C)cc3)cc2c1 -US04578381,6,COc1ccc2[nH]c(=O)cc(CC(N)C(=O)O)c2c1>>NC(Cc1cc(=O)[nH]c2ccc(O)cc12)C(=O)O -US08003662B2,2,CN1CCNCC1.O=C(O)c1cc2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c2s1>>CN1CCN(C(=O)c2cc3nccc(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)c3s2)CC1 -US20120077793A1,2,C1CCNC1.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1F)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1F)C(=O)N1CCCC1 -US20130225673A1,6,CCc1oc2ccccc2c1C(=O)c1cc(C)c(OC)c(C)c1>>CCc1oc2ccccc2c1C(=O)c1cc(C)c(O)c(C)c1 -US20150065464A1,3,CCOC(=O)Cl.Cc1cc2cc(Br)cnc2[nH]1>>CCOC(=O)c1cnc2[nH]c(C)cc2c1 -US08129361B2,3,C#CCO.Cc1cc(C)cc(I)c1>>Cc1cc(C)cc(C#CCO)c1 -US07071173B2,1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)CC(=O)O.ClCI>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)CC(=O)OCCl -US06458784B1,6,COC(=O)CC1Nc2ccc(C(=O)NCc3cccnc3)cc2CN(C)C1=O>>CN1Cc2cc(C(=O)NCc3cccnc3)ccc2NC(CC(=O)O)C1=O -US07067664B1,1,CCC(CC)Nc1nc(C)nc(Cl)c1[N+](=O)[O-].Cc1cc(C)c(O)c(C)n1>>CCC(CC)Nc1nc(C)nc(Oc2c(C)cc(C)nc2C)c1[N+](=O)[O-] -US06063789,9,O=Cc1ccc(OCCCBr)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCCOc1ccc(C=O)cc1 -US20090012055A1,1,CCn1c(=O)[nH]c2c(C)cccc21.C[Si](C)(C)CCOCCl>>CCn1c(=O)n(COCC[Si](C)(C)C)c2c(C)cccc21 -US20070219210A1,2,CC(C)(C)N.COc1ccc(-n2nc(C(=O)[O-])cc2-c2cccnn2)cn1>>COc1ccc(-n2nc(C(=O)NC(C)(C)C)cc2-c2cccnn2)cn1 -US08232410B2,1,CCNCC.Nc1cc(F)c([N+](=O)[O-])cc1[N+](=O)[O-]>>CCN(CC)c1cc(N)c([N+](=O)[O-])cc1[N+](=O)[O-] -US20030119881A1,3,CCC1(c2ccc(F)c(C=O)c2OC)OCCO1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1c(F)ccc(C2(CC)OCCO2)c1OC -US20100331293A1,2,Cc1c(N2CCNCC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1.Cc1ccc(C(=O)Cl)o1>>Cc1ccc(C(=O)N2CCN(c3nc4cc(F)cc(F)c4c(Nc4cncc(N5CCOCC5)c4)c3C)CC2)o1 -US20020082426A1,2,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O.OC1CNCC1SCc1ccccc1>>CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CC(O)C(SCc2ccccc2)C1 -US20120142665A1,6,CCOC(=O)c1nc2cc(NC(=O)c3c(C(=O)N4CCC4)cnn3C)ccn2n1>>Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccn2nc(C(=O)O)nc2c1 -US20110130380A1,1,CC1(C)CC(C=O)CCO1.Nc1ccc(Cl)c(Br)n1>>CC1(C)CC(CNc2ccc(Cl)c(Br)n2)CCO1 -US20140114068A1,7,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NC(=O)c1cnc2ccccc2n1>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NC(=O)c1cnc2ccccc2n1 -US20080249150A1,6,CCC(CC)C(NS(=O)(=O)c1ccc(Cl)s1)c1ccnn1-c1ccc(OC)cc1>>CCC(CC)C(NS(=O)(=O)c1ccc(Cl)s1)c1ccnn1-c1ccc(O)cc1 -US09067921B2,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.C[C@H]1CNCCN1Cc1ccccc1.[C-]#N>>C[C@H]1CN(C2(C#N)CCN(C(=O)OC(C)(C)C)CC2)CCN1Cc1ccccc1 -US20030109459A1,1,COC(=O)C1(CCCCBr)CCCC1.C[S-]>>COC(=O)C1(CCCCSC)CCCC1 -US20030216410A1,3,CC(C)c1cccc(-c2ccc3c(c2)NC(=O)C3)c1.Cc1[nH]c(C=O)c(C)c1C(=O)NCCN1CCCC1>>Cc1[nH]c(C=C2C(=O)Nc3cc(-c4cccc(C(C)C)c4)ccc32)c(C)c1C(=O)NCCN1CCCC1 -US07820704B2,6,COC(=O)c1cccc(CN(c2ccnc(-c3ccc(OCC4CCCCC4)cc3)n2)C2CCCC2)c1>>O=C(O)c1cccc(CN(c2ccnc(-c3ccc(OCC4CCCCC4)cc3)n2)C2CCCC2)c1 -US07199239B2,3,CSc1nccc(Cl)n1.OB(O)c1ccc(Cl)cc1>>CSc1nccc(-c2ccc(Cl)cc2)n1 -US20100234351A1,6,COC(=O)c1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1>>O=C(O)c1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1 -US20130253002A1,3,CC(C)(C)OC(=O)Nc1cc(Br)ccc1Cl.CC1(C)OB(/C=C/C2CC2)OC1(C)C>>CC(C)(C)OC(=O)Nc1cc(/C=C/C2CC2)ccc1Cl -US20130045963A1,1,FC(F)(F)c1nc(Cl)cc(OC2CCC3(CC2)OCCO3)n1.OCCO>>OCCOc1cc(OC2CCC3(CC2)OCCO3)nc(C(F)(F)F)n1 -US20130281428A1,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1OCCN1CCCC1.Nc1ncc(I)cc1Br>>COc1cc(-c2cnc(N)c(Br)c2)ccc1OCCN1CCCC1 -US20140350244A1,1,CN1CCOC2(CCNCC2)C1.Clc1ccc(Cl)nn1>>CN1CCOC2(CCN(c3ccc(Cl)nn3)CC2)C1 -US20100210592A1,3,CC1(COc2ccc(Br)c(F)c2)COC1.CON(C)C(=O)C(NC(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1>>CC1(COc2ccc(C(=O)C(NC(=O)OC(C)(C)C)c3ccc(Cl)c(Cl)c3)c(F)c2)COC1 -US20070244158A1,6,Cc1cc(F)ccc1[C@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(F)ccc1[C@H]1CNCC[C@@H]1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20100174098A1,1,CCC1(COS(C)(=O)=O)COC1.OCCCCO>>CCC1(COCCCCO)COC1 -US07229987B2,1,ClCc1nnc(-c2ccc(OCCCN3CCCCC3)cc2)o1.Cn1c(S)nnc1-c1ccccn1>>Cn1c(SCc2nnc(-c3ccc(OCCCN4CCCCC4)cc3)o2)nnc1-c1ccccn1 -US20120101138A1,2,CC(F)(F)c1coc(Cn2ncc(N)n2)n1.Cc1nc(C(=O)O)c(-c2ccc(F)c(N(C)C)c2)o1>>Cc1nc(C(=O)Nc2cnn(Cc3nc(C(C)(F)F)co3)n2)c(-c2ccc(F)c(N(C)C)c2)o1 -US20080255083A1,1,O=C(CCl)c1ccc2c(c1)CN(C(=O)C(F)(F)F)C2.O=c1cc(OCc2ccccc2)cc[nH]1>>O=C(Cn1ccc(OCc2ccccc2)cc1=O)c1ccc2c(c1)CN(C(=O)C(F)(F)F)C2 -US08318949B2,2,Cc1cncc(CN)n1.Cc1nc(N2CCN(CC(C)C)C2=O)sc1C(=O)O>>Cc1cncc(CNC(=O)c2sc(N3CCN(CC(C)C)C3=O)nc2C)n1 -US20090118280A1,2,NCC1CCCO1.O=S(=O)(Cl)c1ccc(I)cc1>>O=S(=O)(NCC1CCCO1)c1ccc(I)cc1 -US05095014,9,Cc1cccc(Cl)c1OC1CN(C(=O)Cl)C1.[NH4+]>>Cc1cccc(Cl)c1OC1CN(C(N)=O)C1 -US20150073141A1,2,COc1ccc(N)cc1-c1c(Cl)cnn1C.O=C=Nc1ccccc1F>>COc1ccc(NC(=O)Nc2ccccc2F)cc1-c1c(Cl)cnn1C -US20150031708A1,2,CNC.COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2C)cc1C(=O)O>>COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2C)cc1C(=O)N(C)C -US20140323730A1,6,CNC(=O)c1n[nH]c2ccc(C(=O)OC)cc12>>CNC(=O)c1n[nH]c2ccc(C(=O)O)cc12 -US20080319044A1,1,N#Cc1ccc2[nH]ccc2c1.OB(O)CCCCCBr>>N#Cc1ccc2c(ccn2CCCCCB(O)O)c1 -US20120289500A1,2,Cc1ccc(CC(=O)O)cc1.Nn1nc(N2CCOCC2)c2ccccc2c1=O>>Cc1ccc(CC(=O)Nn2nc(N3CCOCC3)c3ccccc3c2=O)cc1 -US07838543B2,1,CC=O.CN(CC1CCNC1)c1nc2ccc(NC(=O)c3ccc(-c4ccc(F)cc4)cc3)cc2s1>>CCN1CCC(CN(C)c2nc3ccc(NC(=O)c4ccc(-c5ccc(F)cc5)cc4)cc3s2)C1 -US20140187548A1,3,CC(C)CNc1nc(Br)cn2ccnc12.OB(O)c1ccccc1>>CC(C)CNc1nc(-c2ccccc2)cn2ccnc12 -US05760233,8,OCCCc1ccccc1Cl>>O=CCCc1ccccc1Cl -US04350637,6,CC(C)C[C@@H](NCc1ccccc1)C(=O)O>>CC(C)C[C@@H](N)C(=O)O -US20150038528A1,2,COC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O.NC[C@H](O)C(=O)O>>O=C(NC[C@H](O)C(=O)O)c1ncc2cc(Oc3ccccc3)ccc2c1O -US20100311965A1,1,Cc1cccc2cnc(Cl)nc12.Nc1ccc2cn[nH]c2c1>>Cc1cccc2cnc(Nc3ccc4cn[nH]c4c3)nc12 -US20070270414A1,1,COC(=O)c1cc(S(C)(=O)=O)c(F)cc1C.O=S1(=O)NCCN1C1CC1>>COC(=O)c1cc(S(C)(=O)=O)c(N2CCN(C3CC3)S2(=O)=O)cc1C -US04423047,1,Fc1cnc(Cl)nc1.Sc1ccccc1>>Fc1cnc(Sc2ccccc2)nc1 -US08536179B2,6,COC(=O)c1cc(Br)cc2c1ccn2C(C)C>>CC(C)n1ccc2c(C(=O)O)cc(Br)cc21 -US20090004185A1,1,C1CNC1.Cc1ccc2nc(Cl)nc(NCc3ccc(NC(=O)C4CCN(Cc5ccccc5)CC4)cc3)c2c1>>Cc1ccc2nc(N3CCC3)nc(NCc3ccc(NC(=O)C4CCN(Cc5ccccc5)CC4)cc3)c2c1 -US06949648B2,1,Cc1cc(N)n(-c2ccncc2)n1.O=C(O)c1cc(F)c(F)cc1Cl>>Cc1cc(Nc2cc(F)c(F)cc2C(=O)O)n(-c2ccncc2)n1 -US05700807,7,COc1ccc(-c2c(C(=O)O)c(=O)n(Cc3ccccc3OC)c3c2oc2cc([N+](=O)[O-])ccc23)cc1>>COc1ccc(-c2c(C(=O)O)c(=O)n(Cc3ccccc3OC)c3c2oc2cc(N)ccc23)cc1 -US20020058644A1,1,FC(F)(F)c1cccc(CBr)c1.c1ccc2[nH]nnc2c1>>FC(F)(F)c1cccc(Cn2nnc3ccccc32)c1 -US06437196B1,1,CCCCCO.ClCC1CO1>>CCCCCOCC1CO1 -US05143931,1,CCCCCCCCCCCBr.O=Cc1ccccc1O>>CCCCCCCCCCCOc1ccccc1C=O -US20050176791A1,2,CC(=O)Cl.Nc1ncc(-c2cccc3ccccc23)o1>>CC(=O)Nc1ncc(-c2cccc3ccccc23)o1 -US05049696,6,CCOC(=O)C1(COCc2ccccc2)CCC1>>CCOC(=O)C1(CO)CCC1 -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)NCc2ccccc2)c(C)c1.FC(F)(F)c1cnc(Cl)c(Cl)c1>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)c(C)c1 -US20140187553A1,3,CCCC[Sn](CCCC)(CCCC)c1nccc(N2CCOCC2)n1.CSc1nnc(-c2ccc3c(c2)c(I)cn3C(=O)OC(C)(C)C)s1>>CSc1nnc(-c2ccc3c(c2)c(-c2nccc(N4CCOCC4)n2)cn3C(=O)OC(C)(C)C)s1 -US20080039476A1,2,CCC1NCCc2sccc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CCC1c2ccsc2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US20100105682A1,1,CCOC(=O)C1CC1C=O.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>CCOC(=O)C1CC1CN1CCN(C(c2ccccc2)c2ccccc2)CC1 -US04010184,2,CCc1cc2c(s1)N(C(=O)Cl)CCN=C2c1ccccc1Cl.CN(C)CCCN>>CCc1cc2c(s1)N(C(=O)NCCCN(C)C)CCN=C2c1ccccc1Cl -US20070287838A1,2,Nc1ccc(Oc2ccnc(N)c2[N+](=O)[O-])cc1C(F)(F)F.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>Nc1nccc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(C(F)(F)F)c2)c1[N+](=O)[O-] -US20050267093A1,6,C[Si](C)(C)C#Cc1ccc(CN2CCCC2)cc1>>C#Cc1ccc(CN2CCCC2)cc1 -US05420273,3,CC(c1ccc2c(c1)C(C)(C)CCO2)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1>>C/C(=C\c1ccccc1)c1ccc2c(c1)C(C)(C)CCO2 -US05166218,4,CC(=O)CCC(C)=O.NCCCc1ccc(C(N)=O)s1>>Cc1ccc(C)n1CCCc1ccc(C(N)=O)s1 -US08003649B2,1,C[C@@H]1CN(c2ccc3nnc(C(F)(F)F)n3n2)CCN1.O=Cc1cccnc1>>C[C@@H]1CN(c2ccc3nnc(C(F)(F)F)n3n2)CCN1Cc1cccnc1 -US07012081B2,1,CCOC(=O)C1CCNCC1.ClCc1ccccc1>>CCOC(=O)C1CCN(Cc2ccccc2)CC1 -US07279470B2,2,CCN(Cc1ccccc1)CC1CCNCC1.O=C(Cl)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1>>CCN(Cc1ccccc1)CC1CCN(C(=O)Oc2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)CC1 -US20080255183A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1csc(OCCc2ccc3c(n2)NCCC3)c1>>CC(C)(C)OC(=O)N1CCCc2ccc(CCOc3cccs3)nc21 -US20090036422A1,2,CC(C)(C)OC(=O)NC(C(=O)O)c1ccccc1.COc1ccc(NCCc2ccc(C(F)(F)F)cc2)cc1OC>>COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)C(NC(=O)OC(C)(C)C)c2ccccc2)cc1OC -US06528528B2,2,COc1ccc(C(=O)Nc2ccc(C)c(C)c2)cc1N.Cc1cccc(N=C=S)c1>>COc1ccc(C(=O)Nc2ccc(C)c(C)c2)cc1NC(=S)Nc1cccc(C)c1 -US20110306606A1,1,Nc1ccc(O)cc1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>O=[N+]([O-])c1ccc(Cl)nc1Nc1ccc(O)cc1 -US06350755B1,2,COc1cccc(S(=O)(=O)NCCC(=O)O)c1.Cn1cnc2c1C(c1ccc(C#N)c(F)c1)NCC2>>COc1cccc(S(=O)(=O)NCCC(=O)N2CCc3ncn(C)c3C2c2ccc(C#N)c(F)c2)c1 -US05409943,2,Cc1cc(C)c(COc2cccnc2N)c(C)c1.S=C=Nc1ccc(Cl)cc1>>Cc1cc(C)c(COc2cccnc2NC(=S)Nc2ccc(Cl)cc2)c(C)c1 -US20140171430A1,2,Cc1cc(C)nc(N2CC3CNCC3C2)n1.Cc1ccc(-n2nccn2)c(C(=O)[O-])n1>>Cc1cc(C)nc(N2CC3CN(C(=O)c4nc(C)ccc4-n4nccn4)CC3C2)n1 -US07214698B2,6,CC(C)(CCn1cnc(-c2ccccc2)c1)NC[C@H](O)c1ccc(OCc2ccccc2)c(NS(=O)(=O)c2ccccc2)c1>>CC(C)(CCn1cnc(-c2ccccc2)c1)NC[C@H](O)c1ccc(O)c(NS(=O)(=O)c2ccccc2)c1 -US20040002492A1,3,CC1(C)OB(c2cccc3c2Sc2ccccc2CC3=O)OC1(C)C.O=c1cc(Cl)oc(N2CCOCC2)c1>>O=C1Cc2ccccc2Sc2c1cccc2-c1cc(=O)cc(N2CCOCC2)o1 -US07094798B1,6,COc1ccc2[nH]c3c(C)c(-c4ccccc4)c4c(c3c2c1)C(=O)NC4=O>>Cc1c(-c2ccccc2)c2c(c3c1[nH]c1ccc(O)cc13)C(=O)NC2=O -US04910218,8,OCc1cc2ccc3c4ccccc4ccc3c2s1>>O=Cc1cc2ccc3c4ccccc4ccc3c2s1 -US05650172,1,CCCCCCC(=O)OCCl.O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F>>CCCCCCC(=O)OCn1c(=O)c(F)cn([C@H]2C[C@H](O)[C@@H](CO)O2)c1=O -US07732463B2,9,CC(C)(C)OC(=O)N1CCC(O)(c2ccccc2Sc2ccc(Cl)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccccc2Sc2ccc(Cl)cc2)CC1 -US08846656B2,3,C=CB1OC(C)(C)C(C)(C)O1.CCn1nc(C2CC2)cc1NCc1c(Cl)nc(OC)nc1OC>>C=Cc1nc(OC)nc(OC)c1CNc1cc(C2CC2)nn1CC -US07115767B2,1,CC(C)=O.CCN(CC)c1ccc(NC(=O)C2(NC(=O)CN)CCc3ccccc3C2)cc1>>CCN(CC)c1ccc(NC(=O)C2(NC(=O)CNC(C)C)CCc3ccccc3C2)cc1 -US20110257399A1,6,Oc1cccc2c(F)c(OCc3ccccc3)c(Cl)cc12>>Oc1c(Cl)cc2c(O)cccc2c1F -US08455488B2,1,CCOC(OCC)[C@H](C)N.O=Cc1cccc2nsnc12>>CCOC(OCC)[C@H](C)NCc1cccc2nsnc12 -US20020193402A1,6,Cc1coc([C@@H]2C[C@@]3(c4ccccc4)[C@H](OCc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC[C@@H]2N3Cc2ccccc2)n1>>Cc1coc([C@@H]2C[C@]3(c4ccccc4)N[C@H]2CC[C@H]3OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1 -US20060264457A1,3,CCOC(=O)CC(=O)CCl.O=Cc1ccc(Cl)cc1Cl>>CCOC(=O)/C(=C\c1ccc(Cl)cc1Cl)C(=O)CCl -US20080255153A1,2,O=CO.[NH3+]CCNC(=O)c1cnn2cc(Cc3ccc(Br)cc3)cnc12>>O=CNCCNC(=O)c1cnn2cc(Cc3ccc(Br)cc3)cnc12 -US20140142085A1,2,COc1ccc2c(c1)NC(=O)C2CC(=O)O.NC(=O)c1cc(-c2cccnc2[C@@H](N)Cc2cc(F)cc(F)c2)ccc1F>>COc1ccc2c(c1)NC(=O)C2CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncccc1-c1ccc(F)c(C(N)=O)c1 -US09156827B2,6,COc1ccc2c(c1C#CC(C)(C)N1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O>>COc1ccc2c(c1C#CC(C)(C)N1CCNCC1)O/C(=C\c1n[nH]c3ccccc13)C2=O -US04707473,7,CC(c1ccccc1)N1c2ccccc2Oc2c(C=O)cccc21>>CC(c1ccccc1)N1c2ccccc2Oc2c(CO)cccc21 -US20040138223A1,2,CCc1ccc(NCc2ccc(N(C)C)cc2)cc1.O=C(O)C1CCc2ccccc21>>CCc1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCc3ccccc32)cc1 -US20070015743A1,1,CN(C)CC(=O)N1CCC[C@H]1COc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12.Cc1cccc(CO)n1>>Cc1cccc(COc2ccc(Nc3ncnc4cccc(OC[C@@H]5CCCN5C(=O)CN(C)C)c34)cc2Cl)n1 -US20080275054A1,7,Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1ncnc2c1cnn2-c1ccc([N+](=O)[O-])cc1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1ncnc2c1cnn2-c1ccc(N)cc1 -US05877120,9,COc1cc(OC)nc(C2(O)OC(=O)c3c(-c4cccs4)ccnc32)n1>>COc1cc(OC)nc(C2OC(=O)c3c(-c4cccs4)ccnc32)n1 -US06130222,2,CC(=O)Cl.CCN(CC)C(=O)c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>CCN(CC)C(=O)c1ccc(C(c2ccccc2)N2CCN(C(C)=O)CC2)cc1 -US20150141427A1,3,Cc1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1I.OB(O)c1cccnc1>>Cc1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cccnc1 -US20100256097A1,1,Cc1nc(Cl)ccc1CBr.O=C1COCCN1CCO>>Cc1nc(Cl)ccc1COCCN1CCOCC1=O -US08389743B2,2,CNCc1ncccc1C.O=C(O)C1CC(O)(c2ccc(CN3CCCC3)c(Cl)c2)C1>>Cc1cccnc1CN(C)C(=O)C1CC(O)(c2ccc(CN3CCCC3)c(Cl)c2)C1 -US08088760B2,2,O=C(Cl)OCc1ccccc1.O=C(O)C1CCNCC1>>O=C(O)C1CCN(C(=O)OCc2ccccc2)CC1 -US07622479B2,4,COc1cccc(C(=O)O)c1.Nc1ccc(-c2ccccc2)nc1N>>COc1cccc(-c2nc3nc(-c4ccccc4)ccc3[nH]2)c1 -US03998834,6,COC(=O)C1(Nc2cccc(OC)c2)CCN(CCc2ccccc2)CC1>>COc1cccc(NC2(C(=O)O)CCN(CCc3ccccc3)CC2)c1 -US20140128390A1,6,C[C@@H]1CN(c2ncnc3[nH]c(-c4ccc(F)cc4)cc23)CCN1C(=O)OC(C)(C)C>>C[C@@H]1CN(c2ncnc3[nH]c(-c4ccc(F)cc4)cc23)CCN1 -US20040048891A1,2,Cc1cc(N)ccc1Oc1ncc(C(F)(F)F)cc1Cl.O=C(Cl)c1cc([N+](=O)[O-])ccc1Cl>>Cc1cc(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)ccc1Oc1ncc(C(F)(F)F)cc1Cl -US04323566,2,CCOC(=O)Cl.CN(C)Cc1ccc(CSCCNc2nc(N)nn2C)s1>>CCOC(=O)Nc1nc(NCCSCc2ccc(CN(C)C)s2)n(C)n1 -US20140135508A1,4,CCc1ccc(-c2ccc(Cl)cc2Cl)cc1C=C1C(=O)C(C)(C)OC1(C)C.OO>>CCc1ccc(-c2ccc(Cl)cc2Cl)cc1C1OC12C(=O)C(C)(C)OC2(C)C -US07709471B2,1,COCC(C)N1CCC(=O)N(C)c2cnc(Cl)nc21.COc1cc(C(=O)NC2CCN(C)CC2)ccc1N>>COCC(C)N1CCC(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc21 -US05635197,3,CN1C(=O)CC[C@]2(C)c3ccc(Br)cc3CC[C@@H]12.COc1ccccc1B(O)O>>COc1ccccc1-c1ccc2c(c1)CC[C@H]1N(C)C(=O)CC[C@]21C -US07557127B2,2,COC(=O)c1ccc(NC2CCNCC2)nc1.O=C=Nc1ccccc1>>COC(=O)c1ccc(NC2CCN(C(=O)Nc3ccccc3)CC2)nc1 -US08022218B2,1,CCC[C@@H]1CC(=O)C2=C(C1)NC(C)=C(C#N)[C@H]2c1cc(Br)c(O)c(OCC)c1.O=[N+]([O-])c1cc(F)c(F)cc1CO>>CCC[C@@H]1CC(=O)C2=C(C1)NC(C)=C(C#N)[C@H]2c1cc(Br)c(OCc2cc(F)c(F)cc2[N+](=O)[O-])c(OCC)c1 -US20100029615A1,1,CCI.O=C(NC1CCCC(c2nc3ccccc3[nH]2)C1)c1ccc2c(c1)OCCO2>>CCn1c(C2CCCC(NC(=O)c3ccc4c(c3)OCCO4)C2)nc2ccccc21 -US20110288066A1,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CC(C)S(=O)(=O)c1cc(Br)ccc1C(=O)N(C)C>>CC(C)S(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)ccc1C(=O)N(C)C -US07015218B1,7,CCN(CC)c1ccc([N+](=O)[O-])cc1C#N>>CCN(CC)c1ccc(N)cc1C#N -US08153658B2,6,COC(=O)CCCCCN1CCC(CN(C(=O)OC(C)(C)C)[C@H](C)c2cccc3ccccc23)C(c2cccc(F)c2)C1>>C[C@H](c1cccc2ccccc12)N(CC1CCN(CCCCCC(=O)O)CC1c1cccc(F)c1)C(=O)OC(C)(C)C -US20110251173A1,3,C[C@@H]1CN(c2ccc(OS(=O)(=O)C(F)(F)F)c(F)c2)C(=O)c2c(N)ncnc2O1.OB(O)c1ccccc1Cl>>C[C@@H]1CN(c2ccc(-c3ccccc3Cl)c(F)c2)C(=O)c2c(N)ncnc2O1 -US04495187,1,CNC.Clc1nc2ccccc2n2cnnc12>>CN(C)c1nc2ccccc2n2cnnc12 -US20050070574A1,10,Cc1c(-c2ccccc2)nc2cc(Cl)ccc2c1C(=O)N[C@@H](C)C1CCCCC1.O=C1CCC(=O)N1Br>>C[C@H](NC(=O)c1c(CBr)c(-c2ccccc2)nc2cc(Cl)ccc12)C1CCCCC1 -US20140094450A1,7,COC(=O)c1ccc(NC2CCCCC2C)c([N+](=O)[O-])c1>>COC(=O)c1ccc(NC2CCCCC2C)c(N)c1 -US06867218B2,3,CCOC(=O)/C=C(\C)c1ccc(Br)cc1.COc1cccc(OC)c1B(O)O>>CCOC(=O)/C=C(\C)c1ccc(-c2c(OC)cccc2OC)cc1 -US20140088124A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=C1CC(OCc2ccccc2)C1>>CCOC(=O)C=C1CC(OCc2ccccc2)C1 -US08008342B2,1,BrCCCC1CCCCC1.O[C@H]1CCCC[C@@H]1N1CCC2(C1)OCCO2>>C1CCC(CCCO[C@H]2CCCC[C@@H]2N2CCC3(C2)OCCO3)CC1 -US20090062322A1,6,FC(F)(F)c1ccc2c(c1)CC1(CCN(Cc3ccccc3)CC1)O2>>FC(F)(F)c1ccc2c(c1)CC1(CCNCC1)O2 -US20060276464A1,1,ClCCN1CCOCC1.O=S(=O)(NC1CCNCC1)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F>>O=S(=O)(NC1CCN(CCN2CCOCC2)CC1)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F -US20040214832A1,6,COc1ccccc1CSCCCOc1ccc(N2CCN(C(=O)OC(C)(C)C)C[C@@H]2COc2ccc3ccccc3c2)cc1>>COc1ccccc1CSCCCOc1ccc(N2CCNC[C@@H]2COc2ccc3ccccc3c2)cc1 -US20110212968A1,1,Cc1cccc(CCN)c1.O=CC1CC1>>Cc1cccc(CCNCC2CC2)c1 -US20060004017A1,1,COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1O.CS(=O)(=O)CCCO>>COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCCCS(C)(=O)=O -US08969565B2,9,CC(C)OC(=O)N1CCC[C@H]1CNc1ccc2ncc(Br)n2n1.[C-]#N>>CC(C)OC(=O)N1CCC[C@H]1CNc1ccc2ncc(C#N)n2n1 -US06204293B1,1,COC(=O)c1ccc(CCl)cc1-c1ccccc1.OCC1CCOC1>>COC(=O)c1ccc(COCC2CCOC2)cc1-c1ccccc1 -US20140350032A1,6,CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)OC(C)(C)C)CC[C@@]54C)[C@]3(C)CC[C@@]2(/C=C/C(=O)NC2(c3ncc(Cl)cn3)CC2)CC1=O>>CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)O)CC[C@@]54C)[C@]3(C)CC[C@@]2(/C=C/C(=O)NC2(c3ncc(Cl)cn3)CC2)CC1=O -US09131693B2,3,COc1nn(C)c(-c2c(F)cccc2F)c1C=O.Cc1cc(F)ccc1[Mg+]>>COc1nn(C)c(-c2c(F)cccc2F)c1C(O)c1ccc(F)cc1C -US20100210642A1,3,C#Cc1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12.NS(=O)(=O)c1ccc(Br)cc1>>NS(=O)(=O)c1ccc(C#Cc2cnn3c(C(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)cc1 -US20110092476A1,7,CC(=O)OC[C@@H](C)n1ccc2c([N+](=O)[O-])cccc2c1=O>>CC(=O)OC[C@@H](C)n1ccc2c(N)cccc2c1=O -US06313312B1,2,CC1(c2cccc(NS(C)(=O)=O)c2)C2CNCC21.O=C(O)CCc1ccsc1>>CC1(c2cccc(NS(C)(=O)=O)c2)C2CN(C(=O)CCc3ccsc3)CC21 -US04056540,7,O=C(c1cc(Cl)ccc1O)c1ccccc1F>>Oc1ccc(Cl)cc1C(O)c1ccccc1F -US20150073011A1,6,C=CCON([C@H]1CN(C(=O)OC(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)C=C1C(N)=O)S(=O)(=O)c1ccccc1[N+](=O)[O-]>>C=CCON([C@H]1CN(C(=O)OC(C)(C)C)[C@H](CO)C=C1C(N)=O)S(=O)(=O)c1ccccc1[N+](=O)[O-] -US20130261101A1,9,CC(=O)c1cc(Cl)c(Br)cc1O.[C-]#N>>CC(=O)c1cc(Cl)c(C#N)cc1O -US20090018134A1,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.O=S(=O)(C1CC1)C1(c2cc(N3CCOCC3)nc(Cl)n2)CCCC1>>Nc1ccc(-c2nc(N3CCOCC3)cc(C3(S(=O)(=O)C4CC4)CCCC3)n2)cc1 -US20040242572A1,2,CN1CCNCC1.N#CCc1ccc(C(=O)O)cc1>>CN1CCN(C(=O)c2ccc(CC#N)cc2)CC1 -US20140274930A1,7,C[C@@H](OC(=O)c1ccc([N+](=O)[O-])cc1)[C@H]1O[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1>>C[C@@H](O)[C@H]1O[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 -US20070003680A1,3,CC(C)CNC(=O)C(C)(C)c1ccc(Br)cc1.Cc1cccc(B(O)O)c1>>Cc1cccc(-c2ccc(C(C)(C)C(=O)NCC(C)C)cc2)c1 -US20110319379A1,2,CC(=O)Cl.CCOC(=O)c1cc(Oc2cnc(N)cn2)c2cn(CC)nc2c1>>CCOC(=O)c1cc(Oc2cnc(NC(C)=O)cn2)c2cn(CC)nc2c1 -US07446222B2,3,CCOC(=O)c1cccc(-c2ccccc2Br)c1.OB(O)c1cc(Cl)ccc1OCc1ccccc1>>CCOC(=O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 -US20090238761A1,1,BrCCCCCOc1cc2ccccc2cn1.Cc1cccc(N2CCNCC2)c1>>Cc1cccc(N2CCN(CCCCCOc3cc4ccccc4cn3)CC2)c1 -US20140296515A1,6,CNc1nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c(-c2ccc(OCCOC(=O)[C@H](C)NC(=O)OC(C)(C)C)cc2)c1C#N>>CNc1nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c(-c2ccc(OCCOC(=O)[C@H](C)N)cc2)c1C#N -US20110092547A1,6,COc1ccc([N+](=O)[O-])c(Cl)n1>>O=[N+]([O-])c1ccc(O)nc1Cl -US07196104B2,6,O=C1c2ccccc2C(=O)N1c1ncccc1CN1CCCCC1>>Nc1ncccc1CN1CCCCC1 -US06215001B1,1,CC(C)(CO)NCCCn1ccnc1.ClCc1ccc(Cl)cc1>>CC(C)(COCc1ccc(Cl)cc1)NCCCn1ccnc1 -US20080146614A1,2,CN(C)Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(O)cc1.O=S(=O)(Cl)CCC(F)(F)F>>CN(C)Cc1c(C(=O)NC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1 -US20050010031A1,6,CCC1CN(C(Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)C(Cc1ccc(F)cc1)NC(=O)C1CN(C(=O)OC(C)(C)C)C1>>CCC1CN(C(Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)C(Cc1ccc(F)cc1)NC(=O)C1CNC1 -US20140114067A1,2,Cc1ccc(C(C)C)cc1N.O=C(O)Cn1c(Cc2ccccc2)nc2ccccc21>>Cc1ccc(C(C)C)cc1NC(=O)Cn1c(Cc2ccccc2)nc2ccccc21 -US08507512B2,7,CCOC(=O)c1cnn(-c2cccc(-c3cc(C)ccc3OCc3ccc(C4=CCN(C(=O)OC(C)(C)C)CC4)cc3)n2)c1C(F)(F)F>>CCOC(=O)c1cnn(-c2cccc(-c3cc(C)ccc3OCc3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc3)n2)c1C(F)(F)F -US20090099183A1,1,COc1ccc(Br)cc1-c1cc(Cl)nc(N)n1.Nc1ccc(CCO)cc1>>COc1ccc(Br)cc1-c1cc(Nc2ccc(CCO)cc2)nc(N)n1 -US04835175,6,CCOC(=O)c1cc2c(C(=O)CN(Cc3ccccc3)C(C)(C)C)ccc(OCc3ccccc3)c2[nH]1>>CC(C)(C)N(CC(=O)c1ccc(OCc2ccccc2)c2[nH]c(C(=O)O)cc12)Cc1ccccc1 -US20150183775A1,6,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](O)CC1>>NC[C@@H]1CC[C@@H](O)CC1 -US20150158826A1,1,C1COCCN1.CC(C)(C)C(=O)Nc1cccc(C(=O)c2ccc3ncc(Cl)nc3c2)c1>>CC(C)(C)C(=O)Nc1cccc(C(=O)c2ccc3ncc(N4CCOCC4)nc3c2)c1 -US20050153996A1,3,FC(F)(F)Oc1cccc(Br)c1.OCc1cccc(B(O)O)c1>>OCc1cccc(-c2cccc(OC(F)(F)F)c2)c1 -US20060069132A1,2,CCN1N=C(C(C)(C)C)CC1C(=O)O.CCOC(=O)c1ccc(F)c(N)c1>>CCOC(=O)c1ccc(F)c(NC(=O)C2CC(C(C)(C)C)=NN2CC)c1 -US20060128750A1,1,Cn1ccnc1C=O.NCc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1>>Cn1ccnc1CNCc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1 -US20150175602A1,2,CC(=O)OC(C)=O.CC(C)Nc1nc2c(nc1N1CCC([C@@H](F)c3ccc(F)cc3F)CC1)CCNC2>>CC(=O)N1CCc2nc(N3CCC([C@@H](F)c4ccc(F)cc4F)CC3)c(NC(C)C)nc2C1 -US07652015B2,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Cc1cc([N+](=O)[O-])cnc1Cl>>Cc1cc([N+](=O)[O-])cnc1OC1CCN(C(=O)OC(C)(C)C)CC1 -US20030125563A1,7,CC(CCC1=CCCC1=O)OCc1ccccc1>>CC(CCC1CCCC1=O)OCc1ccccc1 -US06355662B1,4,C#CCCC(=O)OC.CC(C)CC(C=NO)NC(=O)OCc1ccccc1>>COC(=O)CCc1cc(C(CC(C)C)NC(=O)OCc2ccccc2)no1 -US20100113491A1,1,Clc1ncc(Br)cn1.Nc1ccc(S)cc1>>Nc1ccc(Sc2ncc(Br)cn2)cc1 -US20040225123A1,6,COc1ccc2cc(-c3ccccc3)ccc2c1>>Oc1ccc2cc(-c3ccccc3)ccc2c1 -US05728835,2,CCOC(=O)Cl.COc1ccccc1N(CCN1CCC(C(=O)c2ccc(F)cc2)CC1)C(=O)c1ccc(N)cc1>>CCOC(=O)Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c2ccccc2OC)cc1 -US20120184549A1,3,CC(C)n1cc(Br)ccc1=O.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>CC(C)n1cc(-c2ccc([C@H](C)N3CC[C@](CC(C)(C)O)(c4ccccc4)OC3=O)cc2)ccc1=O -US20090281079A1,3,CC1(C)OB(c2cc(F)c(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2F)OC1(C)C.Cc1c(Br)c2c(N)ncnn2c1CN1CCOCC1>>Cc1c(-c2cc(F)c(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2F)c2c(N)ncnn2c1CN1CCOCC1 -US20100081670A1,1,CC(O)C1CC1.O=S(=O)(Nc1ncc(Cl)nc1Cl)c1cccc(Cl)c1Cl>>CC(Oc1nc(Cl)cnc1NS(=O)(=O)c1cccc(Cl)c1Cl)C1CC1 -US08034949B2,1,CCCCNC.O=C(N[C@@H]1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1ccc(OC(F)(F)F)cc1>>CCCCN(C)c1ccc(C(c2ccc(Cl)cc2)N2CC[C@@H](NC(=O)c3ccc(OC(F)(F)F)cc3)C2)cc1 -US20060020003A1,2,CCCc1c(C(=O)Cl)cnn1-c1ccccc1.COC(=O)COc1ccc(-c2ccc(C[NH3+])cc2)cc1Br>>CCCc1c(C(=O)NCc2ccc(-c3ccc(OCC(=O)OC)c(Br)c3)cc2)cnn1-c1ccccc1 -US08173650B2,1,CCn1c(CO)nc2c(N3CCOCC3)nc(Cl)nc21.Cc1nc2ccccc2[nH]1>>CCn1c(CO)nc2c(N3CCOCC3)nc(-n3c(C)nc4ccccc43)nc21 -US05401739,1,COc1cccc(CCl)c1.O=C1CCCCN1>>COc1cccc(CN2CCCCC2=O)c1 -US20020028797A1,1,C1CC2(CCN1)OCCO2.O=S(=O)(NCCO)c1ccc(F)cc1>>O=S(=O)(NCCO)c1ccc(N2CCC3(CC2)OCCO3)cc1 -US20020086999A1,1,COc1ccc(CCBr)cc1.Clc1ccc2c(n1)N(C1CCNCC1)CC2>>COc1ccc(CCN2CCC(N3CCc4ccc(Cl)nc43)CC2)cc1 -US08785481B2,6,COc1ccc2c(nnn2CC2CC2)c1Br>>Oc1ccc2c(nnn2CC2CC2)c1Br -US20090093480A1,9,Fc1ccc(Nc2cc(Cl)nc(Cl)n2)cc1C(F)(F)F.NN>>NNc1cc(Nc2ccc(F)c(C(F)(F)F)c2)nc(Cl)n1 -US04469868,1,CC(O)CN.CCc1nc(Cl)c2c(n1)c(C)nn2C>>CCc1nc(NCC(C)O)c2c(n1)c(C)nn2C -US20050148643A1,4,C[C@H](O)C(=O)O.Nc1ccc([N+](=O)[O-])cc1N>>C[C@H](O)c1nc2cc([N+](=O)[O-])ccc2[nH]1 -US20090312310A1,1,CC1(C)OC[C@H](C=O)O1.C[C@H]1CN(C(=O)OC(C)(C)C)CCN1>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1C[C@H]1COC(C)(C)O1 -US20030162788A1,2,CC1(C)CCN(c2ccc(CN)cc2)CC1.Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O>>Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)NCc1ccc(N2CCC(C)(C)CC2)cc1 -US20120258973A1,2,C[C@H](N)c1ccccc1.Cn1nc(-c2ccccc2F)c2c(C(F)(F)F)cc(OCC(=O)O)nc21>>C[C@H](NC(=O)COc1cc(C(F)(F)F)c2c(-c3ccccc3F)nn(C)c2n1)c1ccccc1 -US20090298878A1,6,CC(C)(C)OC(=O)N1c2ccccc2C[C@H]1CON=C1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1>>O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCC(=NOC[C@@H]2Cc3ccccc3N2)CC1 -US06281227B1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1=O.O=S(=O)(c1ccccc1)n1c(CBr)cc2nc(Cl)ccc21>>CC(C)(C)OC(=O)N[C@H]1CCN(Cc2cc3nc(Cl)ccc3n2S(=O)(=O)c2ccccc2)C1=O -US05792763,1,CC(=O)CCCCl.CNC>>CC(=O)CCCN(C)C -US20100016311A1,3,CCOP(=O)(Cc1ccc(C(=O)OC)cc1)OCC.O=Cc1cnc2ccccc2c1>>COC(=O)c1ccc(/C=C/c2cnc3ccccc3c2)cc1 -US20150191463A1,1,Cc1n[nH]c2cc(Br)ccc12.Fc1cccc(Cl)c1CCl>>Cc1nn(Cc2c(F)cccc2Cl)c2cc(Br)ccc12 -US20090270384A1,8,COc1cc(CO)ccc1F>>COc1cc(C=O)ccc1F -US08211919B2,7,CCOC(=O)CN(CC(=O)Nc1ccc(-c2ccncc2)cc1)c1ccccc1>>O=C(CN(CCO)c1ccccc1)Nc1ccc(-c2ccncc2)cc1 -US08906944B2,6,Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCCNC(=O)OC(C)(C)C)c[nH]4)c3)cc2)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCCN)c[nH]4)c3)cc2)c1 -US20090023763A1,3,C#C[Si](C)(C)C.Nc1nc(-c2cccc(F)c2)c(-c2ccncc2)cc1Br>>C[Si](C)(C)C#Cc1cc(-c2ccncc2)c(-c2cccc(F)c2)nc1N -US04243806,1,O=[N+]([O-])c1cc(CCl)ccc1Cl.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=[N+]([O-])c1cc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)ccc1Cl -US20040259912A1,2,COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccccc1F.COc1ccc(N=C=O)cc1OC>>COC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OC(c1ccccc1)c1ccccc1F -US20120302567A1,3,C#Cc1csc2c(SC)ncnc12.CCOC(=O)c1ccc(C)c(I)c1>>CCOC(=O)c1ccc(C)c(C#Cc2csc3c(SC)ncnc23)c1 -US20140057896A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCc2c(sc3c2CCCC3)C1=O.Cn1cc(Br)nc(Nc2ccc(C3CCN(C4COC4)CC3)cc2)c1=O>>CC(=O)OCc1c(-c2cn(C)c(=O)c(Nc3ccc(C4CCN(C5COC5)CC4)cc3)n2)cccc1N1CCc2c(sc3c2CCCC3)C1=O -US07834030B2,7,CCOC(=O)c1sc(-c2ccc(C(F)(F)F)cc2)nc1CN1CCC(C(F)(F)F)CC1>>OCc1sc(-c2ccc(C(F)(F)F)cc2)nc1CN1CCC(C(F)(F)F)CC1 -US04064257,9,CC(C)(C)C#CCCO.ClC(Cl)(Cl)Cl>>CC(C)(C)C#CCCCl -US05994378,1,CC(C)(C)c1csc(-c2cc3cc(C(=O)CBr)ccc3o2)n1.N#Cc1c[nH]c2ccccc12>>CC(C)(C)c1csc(-c2cc3cc(C(=O)Cn4cc(C#N)c5ccccc54)ccc3o2)n1 -US07589232B2,2,CCCCc1ccc(C#Cc2ccc(CNCc3ccc(C(=O)OC)cc3)cc2)cc1.O=C(Cl)CCC1CCCC1>>CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(C(=O)OC)cc3)C(=O)CCC3CCCC3)cc2)cc1 -US08404709B2,3,CC(=O)CC(C)=O.N#Cc1ccc(C=O)c(OC(F)(F)F)c1>>CC(=O)C(=Cc1ccc(C#N)cc1OC(F)(F)F)C(C)=O -US20110112120A9,1,CC1CC(O)CCO1.CCCCc1nc(C)n(-c2ccc(O)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1>>CCCCc1nc(C)n(-c2ccc(OC3CCOC(C)C3)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1 -US20100041676A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Nc1ncnc2c(I)nn(-c3ccc([N+](=O)[O-])cc3)c12>>CC(C)(C)OC(=O)N1CC=C(c2nn(-c3ccc([N+](=O)[O-])cc3)c3c(N)ncnc23)CC1 -US20090137548A1,7,Cc1cc(C(=O)O)ccc1-c1ccc(Cl)c(-c2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)c1>>Cc1cc(CO)ccc1-c1ccc(Cl)c(-c2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)c1 -US20090082434A1,9,Cc1c(Cl)cc(C(C)C)c2c1CC(CN=[N+]=[N-])O2>>Cc1c(Cl)cc(C(C)C)c2c1CC(CN)O2 -US05041448,2,Nc1cncnc1NCc1ccc(F)cc1.O=C(O)CC1CCN(Cc2ccccc2)CC1>>O=C(CC1CCN(Cc2ccccc2)CC1)Nc1cncnc1NCc1ccc(F)cc1 -US20090281092A1,1,CI.COc1cc(C(=O)NC2CCCNCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NC2CCCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20140288046A1,1,CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1.CC1CCNC1>>CC1CCN(c2nc(C(C)(C)C)nc3c2nnn3Cc2ccccc2Cl)C1 -US06670386B2,6,CC(C)(C)[C@H]1N(c2ccc(C#N)c3ccccc23)C(=O)[C@@H]2C[C@@H](OCc3ccccc3)CN12>>CC(C)(C)[C@H]1N(c2ccc(C#N)c3ccccc23)C(=O)[C@@H]2C[C@@H](O)CN12 -US20090018134A1,2,Cc1csc(S(=O)(=O)C2(c3cc(N4CCOC[C@@H]4C)nc(-c4ccc(N)cc4)n3)CCC2)n1.O=C(Cl)Oc1ccccc1>>Cc1csc(S(=O)(=O)C2(c3cc(N4CCOC[C@@H]4C)nc(-c4ccc(NC(=O)Oc5ccccc5)cc4)n3)CCC2)n1 -US20140288123A1,6,COC(=O)c1ccc(C(C)Oc2ccccc2)cc1>>CC(Oc1ccccc1)c1ccc(C(=O)O)cc1 -US20130030012A1,1,O=Cc1ccc(F)c(F)c1.Oc1ccc(F)c(C(F)(F)F)c1>>O=Cc1ccc(Oc2ccc(F)c(C(F)(F)F)c2)c(F)c1 -US20130217666A1,3,C#CC(C)(C)O.NC(=O)c1nc2n(c1CNC1COC1)CCOc1ccc(Br)cc1-2>>CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(CNC3COC3)n1CCO2 -US20080108665A1,8,CSCc1ccc(Cl)nc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1ccc(Cl)nc1 -US03992535,2,COC(=O)C1=C(O)c2ccc3ccccc3c2S(=O)(=O)N1C.Nc1cccc(F)c1>>CN1C(C(=O)Nc2cccc(F)c2)=C(O)c2ccc3ccccc3c2S1(=O)=O -US20150038437A1,8,CCCC(O)c1ccc2c(ccn2C)c1OCc1ccccc1>>CCCC(=O)c1ccc2c(ccn2C)c1OCc1ccccc1 -US20140163012A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]1Cc2oc3cc(Br)ccc3c2CN1>>C[C@@H]1Cc2oc3cc(Br)ccc3c2CN1C(=O)OC(C)(C)C -US08173650B2,1,Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CBr)n(C)c2n1.FC1(F)CCNCC1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(F)(F)CC3)n(C)c2n1 -US20050107347A1,6,COC(=O)C(O)Cc1cc(Br)c(Oc2cc(I)c(OC)c(C(C)C)c2)c(Br)c1>>COC(=O)C(O)Cc1cc(Br)c(Oc2cc(I)c(O)c(C(C)C)c2)c(Br)c1 -US20080312234A1,6,CCCCCc1nc(C(F)(F)F)ccc1C=CC(=O)OC>>CCCCCc1nc(C(F)(F)F)ccc1C=CC(=O)O -US04812459,8,CC1(C)Oc2ccncc2[C@@H](N2CCCC2=O)[C@@H]1O.O=C(OO)c1cccc(Cl)c1>>CC1(C)Oc2cc[n+]([O-])cc2[C@@H](N2CCCC2=O)[C@@H]1O -US04189598,1,CC(C)C(C(=O)O)C1=Cc2ccccc2C1.CS(=O)(=O)OC(C#N)c1cccc(Oc2ccccc2)c1>>CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)C1=Cc2ccccc2C1 -US20050043331A1,2,CCOC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)c(CCCO)n1C.CS(=O)(=O)Cl>>CCOC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)c(CCCOS(C)(=O)=O)n1C -US08268859B2,5,CS(=O)(=O)c1ccc(N)c(Br)n1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CS(=O)(=O)c1ccc(NC(=O)C(F)(F)F)c(Br)n1 -US20120142665A1,2,COC1CNC1.Cn1ncc(C(=O)O)c1C(=O)Nc1ccn2nc(-c3ccccc3)nc2c1>>COC1CN(C(=O)c2cnn(C)c2C(=O)Nc2ccn3nc(-c4ccccc4)nc3c2)C1 -US06225330B1,7,COCC(=O)NC1CCC(CNc2nc3c(s2)CCOc2ccccc2-3)CC1>>COCCNC1CCC(CNc2nc3c(s2)CCOc2ccccc2-3)CC1 -US05929281,1,Brc1ccccc1.C1CNCCN1>>c1ccc(N2CCNCC2)cc1 -US04710573,1,CN1CCC(c2n[nH]c3ccccc23)CC1.Fc1ccc(Cl)cc1>>CN1CCC(c2nn(-c3ccc(Cl)cc3)c3ccccc23)CC1 -US06858739B2,7,COc1ccc(-c2cc3cc(F)c(F)cc3[nH]2)cc1NS(=O)(=O)c1cccc([N+](=O)[O-])c1>>COc1ccc(-c2cc3cc(F)c(F)cc3[nH]2)cc1NS(=O)(=O)c1cccc(N)c1 -US20120165310A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ncnc2c1c(I)cn2[C@H]1C[C@@H](CO)C1>>Cc1ccc(S(=O)(=O)OCC2CC(n3cc(I)c4c(N)ncnc43)C2)cc1 -US20040067935A1,6,CCc1cc(NC(=O)NC[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)cc(-c2nnnn2C)c1>>CCc1cc(NC(=O)NC[C@H]2CCCNC2)cc(-c2nnnn2C)c1 -US07745641B2,3,C=CC(=O)OC.Nc1c(I)cc(Br)c2c1C(=O)NC2=O>>COC(=O)/C=C/c1cc(Br)c2c(c1N)C(=O)NC2=O -US20100063077A1,1,Clc1ncc(Br)cn1.Nc1ccc(C(=O)C(F)(F)F)cc1>>O=C(c1ccc(Nc2ncc(Br)cn2)cc1)C(F)(F)F -US07973082B2,2,CC(C)=CC(O)CCN.COC(=O)Cl>>COC(=O)NCCC(O)C=C(C)C -US20100240677A1,6,COc1cc(COC(C)=O)nnc1OC>>COc1cc(CO)nnc1OC -US07291635B2,2,CC(=O)N[C@@H](Cc1ccccc1)C(=O)O.COc1ccc(CN2C(=O)CN(c3ccc(C[C@H](N)C(=O)OCc4ccccc4)cc3)S2(=O)=O)cc1>>COc1ccc(CN2C(=O)CN(c3ccc(C[C@H](NC(=O)[C@H](Cc4ccccc4)NC(C)=O)C(=O)OCc4ccccc4)cc3)S2(=O)=O)cc1 -US08729078B2,7,CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c(Nc5ccc(C(C)(C)O)cc5)n4)c3C=O)ncc2c1>>CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c(Nc5ccc(C(C)(C)O)cc5)n4)c3CO)ncc2c1 -US20010020114A1,3,C=C(C)COC(C)=O.c1ccccc1>>CC(=O)OCC(C)(C)c1ccccc1 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.O=Cc1cccc(Oc2cccc(C(F)(F)F)c2)c1>>CC(C)C(=O)Nc1cccc(C2CCN(Cc3cccc(Oc4cccc(C(F)(F)F)c4)c3)CC2)c1 -US06489324B2,2,COc1ccc(S(=O)(=O)Cl)cc1.C[C@@H]1[C@H](C(=O)NOCc2ccccc2)NCCN1S(C)(=O)=O>>COc1ccc(S(=O)(=O)N2CCN(S(C)(=O)=O)[C@H](C)[C@@H]2C(=O)NOCc2ccccc2)cc1 -US20090069327A1,1,CSc1cc(-c2cncnc2Cl)ncn1.Cc1ccc(NC(=O)OC(C)(C)C)cc1N>>CSc1cc(-c2cncnc2Nc2cc(NC(=O)OC(C)(C)C)ccc2C)ncn1 -US04192871,7,CCCN(CCC)CC(=O)O[C@H]1C[C@]2(C)[C@@H](C(C)=O)CC[C@H]2[C@@H]2CC[C@H]3CC(=O)CC[C@]3(C)[C@@H]12>>CCCN(CCC)CC(=O)O[C@H]1C[C@]2(C)[C@@H](C(C)=O)CC[C@H]2[C@@H]2CC[C@H]3C[C@H](O)CC[C@]3(C)[C@@H]12 -US08969341B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(Cl)ccc1O>>CC(C)(C)OC(=O)Nc1cc(Cl)ccc1O -US04851419,7,CN(C)c1ccccc1S(=O)c1nc2cc([N+](=O)[O-])ccc2[nH]1>>CN(C)c1ccccc1S(=O)c1nc2cc(N)ccc2[nH]1 -US08378092B2,1,Fc1ccc(Br)c(F)c1Br.O=C1CCCN1>>O=C1CCCN1c1ccc(F)c(Br)c1F -US20060235222A1,2,CCC(CC)(c1ccc(F)cc1)c1c(C)[nH]c2c(N)cccc12.CS(=O)(=O)Cl>>CCC(CC)(c1ccc(F)cc1)c1c(C)[nH]c2c(NS(C)(=O)=O)cccc12 -US20060264460A1,4,CCOC(C#CC=O)OCC.[N-]=[N+]=[N-]>>CCOC(OCC)c1[nH]nnc1C=O -US06720423B2,6,CCOC(=O)CCc1cc(Br)cc2c1OCC2(C)C>>CC1(C)COc2c(CCC(=O)O)cc(Br)cc21 -US04996215,3,C=O.CS(=O)(=O)Nc1ccc(C(=O)C2CCNCC2)cc1.Cc1ccco1>>Cc1ccc(CN2CCC(C(=O)c3ccc(NS(C)(=O)=O)cc3)CC2)o1 -US07732446B1,4,CCOC(=O)C(=O)CBr.COc1cc2c(NC(N)=S)cnc(CNC(=O)OC(C)(C)C)c2cc1OC>>CCOC(=O)c1csc(Nc2cnc(CNC(=O)OC(C)(C)C)c3cc(OC)c(OC)cc23)n1 -US06303630B1,2,CNc1ccccc1.O=S(=O)(Cl)c1ccccc1C(F)(F)F>>CN(c1ccccc1)S(=O)(=O)c1ccccc1C(F)(F)F -US06399641B1,2,Nc1nnn(C(F)F)n1.O=C(Cl)C(c1ccccc1)c1ccccc1>>O=C(Nc1nnn(C(F)F)n1)C(c1ccccc1)c1ccccc1 -US08362003B2,6,CC(C)(C)OC(=O)N[C@@H]1CCN([C@@H]2CCCC[C@@H]2N=[N+]=[N-])C1>>[N-]=[N+]=N[C@H]1CCCC[C@H]1N1CC[C@@H](N)C1 -US07368578B2,6,CCOC(=O)Cc1ccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4/C=C/c4cn(CC)cn4)cc3OC)c(C)o2)cc1>>CCn1cnc(/C=C/c2cn(-c3ccccc3)nc2OCc2ccc(OCc3nc(-c4ccc(CC(=O)O)cc4)oc3C)c(OC)c2)c1 -US08921404B2,2,CC1CCN(C(=O)Cl)CC1.Oc1noc2nc(Cl)ccc12>>CC1CCN(C(=O)Oc2noc3nc(Cl)ccc23)CC1 -US20050137231A1,1,C1CCNC1.O=c1oc2c(I)c(O)ccc2c(Cc2ccc(OCCBr)cc2)c1-c1ccc(Cl)cc1Cl>>O=c1oc2c(I)c(O)ccc2c(Cc2ccc(OCCN3CCCC3)cc2)c1-c1ccc(Cl)cc1Cl -US04567175,1,CC(=O)O.COc1ccc([C@@H]2Sc3cc(Cl)ccc3N(CCN(C)C)C(=O)[C@@H]2O)cc1>>COc1ccc([C@@H]2Sc3cc(Cl)ccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1 -US08822471B2,2,Fc1cc(C(F)(F)F)cnc1N1CCC(NC2CC2)CC1.O=C(O)c1ccc(-n2cncn2)c(F)c1>>O=C(c1ccc(-n2cncn2)c(F)c1)N(C1CC1)C1CCN(c2ncc(C(F)(F)F)cc2F)CC1 -US20110082129A1,2,CCS(=O)(=O)Cl.Cn1c(-c2cncc(CN)c2)cc2ccccc21>>CCS(=O)(=O)NCc1cncc(-c2cc3ccccc3n2C)c1 -US06479514B1,1,Cc1c(SCCCCl)ccnc1CCl.Nc1cnc2ccccc2c1>>Cc1c(SCCCCl)ccnc1CNc1cnc2ccccc2c1 -US04335137,3,CC(=O)Cl.ClC(Cl)=Cc1cccs1>>CC(=O)c1ccc(C=C(Cl)Cl)s1 -US08629166B2,1,O=C(O)c1cnc(Cl)c(I)c1.OCC(F)(F)F>>O=C(O)c1cnc(OCC(F)(F)F)c(I)c1 -US08658801B2,9,COC(=O)c1c(N)c(Br)cc2cn[nH]c12.[C-]#N>>COC(=O)c1c(N)c(C#N)cc2cn[nH]c12 -US06660742B2,1,BrCc1ccccc1.Nc1cc(Cl)c([N+](=O)[O-])cc1O>>Nc1cc(Cl)c([N+](=O)[O-])cc1OCc1ccccc1 -US09132130B2,1,CCOC1CNCCO1.COc1ccc(CSc2nc(Cl)c3ncn(C)c3n2)cc1[N+](=O)[O-]>>CCOC1CN(c2nc(SCc3ccc(OC)c([N+](=O)[O-])c3)nc3c2ncn3C)CCO1 -US20140155594A1,7,O=C(CN1CCCC1)Nc1ccc(Br)cc1>>Brc1ccc(NCCN2CCCC2)cc1 -US04780464,1,CCc1nnc2c(Cl)nc3ccccc3n12.NC1CC1>>CCc1nnc2c(NC3CC3)nc3ccccc3n12 -US06350892B1,7,CCCCCCCCCCCCN(CCCC(=O)OCC)CCOc1ccc(/C=C/C(O)C(F)(F)F)cc1>>CCCCCCCCCCCCN(CCCC(=O)OCC)CCOc1ccc(CCC(O)C(F)(F)F)cc1 -US09156840B2,1,CC(C)(C)OC(=O)[C@H](c1ccccc1)N1CN(c2ccccc2)C2(CCNCC2)C1=O.O=C(CCCCl)c1ccccc1>>CC(C)(C)OC(=O)[C@H](c1ccccc1)N1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccccc3)CC2)C1=O -US20150239842A1,2,Cc1c(C(=O)O)nc(-c2ccc(N)nc2)nc1-c1ccnn1C.Cc1cc(C)c(CN)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2nc(-c3ccc(N)nc3)nc(-c3ccnn3C)c2C)c(=O)[nH]1 -US20100256356A1,7,COc1ccc(Cn2nc(C3=CCN(C(=O)OC(C)(C)C)CC3)c3c(Oc4ccc(N)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(C3CCN(C(=O)OC(C)(C)C)CC3)c3c(Oc4ccc(N)cc4F)ccnc32)cc1 -US06897231B2,3,Nc1ccc(Br)cc1.O=C(Cl)c1ccc(F)cc1>>Nc1ccc(Br)cc1C(=O)c1ccc(F)cc1 -US20110009261A1,2,C1CSCN1.N#Cc1c(F)cccc1S(=O)(=O)Cl>>N#Cc1c(F)cccc1S(=O)(=O)N1CCSC1 -US20030144333A1,7,COc1c(C)cc(Cl)cc1[N+](=O)[O-]>>COc1c(C)cc(Cl)cc1N -US20100266714A1,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cc(-c2ccc(C)cn2)c1.Cc1ncc(Br)cn1>>COC(=O)c1cc(-c2cnc(C)nc2)cc(-c2ccc(C)cn2)c1 -US20110319378A1,2,CCC(CC)N1C(=O)[C@@](C)(CC(O)C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1.COc1ccc(CN)c(OC)c1>>CCC(CC)N1C(=O)[C@@](C)(CC(O)C(=O)NCc2ccc(OC)cc2OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US06734206B1,7,COC(=O)COCCCCN1C(=O)CC[C@H]1CCC(=O)Cc1cccc(Cl)c1>>COC(=O)COCCCCN1C(=O)CC[C@H]1CCC(O)Cc1cccc(Cl)c1 -US05998412,1,CC(C)(C)OC(=O)CCl.O=S1(=O)NCCN1Cc1ccc(-c2ccccc2)cc1>>CC(C)(C)OC(=O)CN1CCN(Cc2ccc(-c3ccccc3)cc2)S1(=O)=O -US20100190761A1,1,CC(C)(C)C(c1ccc(OCc2ccccn2)cc1)c1ccc(-c2n[nH]c(=O)o2)cc1.CI>>Cn1nc(-c2ccc(C(c3ccc(OCc4ccccn4)cc3)C(C)(C)C)cc2)oc1=O -US20130296312A1,3,CS(=O)(=O)Nc1cccc(B(O)O)c1.Nc1nc2cccc(Br)n2n1>>CS(=O)(=O)Nc1cccc(-c2cccc3nc(N)nn23)c1 -US20070225271A1,6,COc1cc(OC)nc(NC2CCN(C(=O)OC(C)(C)C)CC2)n1>>COc1cc(OC)nc(NC2CCNCC2)n1 -US20100075948A1,2,CC(=O)Cl.CC(C)(CCN)CC1NC(C(=O)NCC[C@H]2COC(C)(C)O2)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F>>CC(=O)NCCC(C)(C)CC1NC(C(=O)NCC[C@H]2COC(C)(C)O2)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F -US20100152160A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CNc2cc(Cl)c([N+](=O)[O-])c([N+](=O)[O-])c2O1>>CCOC(=O)C1CN(C(=O)OC(C)(C)C)c2cc(Cl)c([N+](=O)[O-])c([N+](=O)[O-])c2O1 -US05159103,6,COc1ccc2c(c1)CC(NCc1ccccc1)CC2>>Oc1ccc2c(c1)CC(NCc1ccccc1)CC2 -US05792769,6,CC(C)(C)OC(=O)N1CCN(CCOc2cccc(OS(=O)(=O)c3ccccc3Cl)c2)CC1>>O=S(=O)(Oc1cccc(OCCN2CCNCC2)c1)c1ccccc1Cl -US20020156311A1,7,CS(=O)(=O)Nc1cccc(N(Cc2ccccc2)Cc2ccccc2)c1C=O>>CS(=O)(=O)Nc1cccc(N(Cc2ccccc2)Cc2ccccc2)c1CO -US20090082372A1,2,CNC(=O)c1ccc(C#Cc2ccc(OC(F)(F)F)c(C(=O)O)c2)cc1.NC(CO)Cc1n[nH]c2c(C(F)(F)F)cccc12>>CNC(=O)c1ccc(C#Cc2ccc(OC(F)(F)F)c(C(=O)NC(CO)Cc3n[nH]c4c(C(F)(F)F)cccc34)c2)cc1 -US08227507B2,6,CCOC(=O)c1ccc(-c2ccc(OCCCO[Si](C)(C)C(C)(C)C)c(-c3ccc(N(CC)CC)c(CC)c3)c2)cc1>>CCOC(=O)c1ccc(-c2ccc(OCCCO)c(-c3ccc(N(CC)CC)c(CC)c3)c2)cc1 -US20060084690A1,2,Nc1cnccn1.O=C(O)CCc1cnoc1-c1ccccc1>>O=C(CCc1cnoc1-c1ccccc1)Nc1cnccn1 -US20150210697A1,1,COC(=O)N1CC[C@@H](N)[C@H](O)C1.N#Cc1cc(Br)c(Cl)c(Br)c1>>COC(=O)N1CC[C@@H](Nc2cc(C#N)cc(Br)c2Cl)[C@H](O)C1 -US05990105,1,CNC.O=S(=O)(c1ccccc1)c1cc(Br)nc(Br)c1>>CN(C)c1cc(S(=O)(=O)c2ccccc2)cc(Br)n1 -US04889857,1,C1CCN(CC2CNCCO2)C1.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2c(F)c(N3CCOC(CN4CCCC4)C3)c(F)cc2c1=O -US20050038047A1,1,Fc1cc2c(Cl)ncnc2cn1.NC1CCCCCC1>>Fc1cc2c(NC3CCCCCC3)ncnc2cn1 -US07253198B2,2,CCOC(=O)c1cc(N)c2[nH]cc(CC)c2c1.O=S(=O)(Cl)CCCCCl>>CCOC(=O)c1cc(NS(=O)(=O)CCCCCl)c2[nH]cc(CC)c2c1 -US07625908B2,2,CN[C@@H](C)COc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12.COCC(=O)O>>COCC(=O)N(C)[C@@H](C)COc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12 -US20100105683A1,1,O=[N+]([O-])c1ccc(F)cc1O.OCc1cccnc1>>O=[N+]([O-])c1ccc(F)cc1OCc1cccnc1 -US08791147B2,1,C[C@@H](NCc1ccc(OCc2ccc(F)nc2)nc1)c1ccccc1.C[O-]>>COc1ccc(COc2ccc(CN[C@H](C)c3ccccc3)cn2)cn1 -US20100249123A1,2,COc1ccc(C(=O)Cl)cc1OC.Cc1cc(N)ccc1C(C)(C)C#N>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(C)c2)cc1OC -US20100240638A1,9,CN(C)c1nc(Cl)nc2c1CN(C(=O)OC(C)(C)C)C2>>CN(C)c1ncnc2c1CN(C(=O)OC(C)(C)C)C2 -US08993586B2,6,COC(=O)c1ccc2ccnc(OC)c2c1>>COc1nccc2ccc(C(=O)O)cc12 -US20130338152A1,1,BrCC1CCCO1.Oc1cccc(Br)c1F>>Fc1c(Br)cccc1OCC1CCCO1 -US20100075959A1,2,CC(=O)Cl.COc1ccc(N2CCNCC2)c2sc(NC(=O)c3ccc(C)s3)nc12>>COc1ccc(N2CCN(C(C)=O)CC2)c2sc(NC(=O)c3ccc(C)s3)nc12 -US20150065482A1,9,CCNc1nccc2c1c(C(=O)OC)nn2-c1cccc(C#C[C@]2(O)CCN(C)C2=O)c1.N>>CCNc1nccc2c1c(C(N)=O)nn2-c1cccc(C#C[C@]2(O)CCN(C)C2=O)c1 -US04833150,1,OCCBr.c1ccc2c(c1)CNC2>>OCCN1Cc2ccccc2C1 -US20100261755A1,7,COC(=O)c1ccnc(-c2cc(Cl)cc(Cl)c2)c1>>COC(=O)C1CCNC(c2cc(Cl)cc(Cl)c2)C1 -US20070249630A1,1,CC1(C)OCc2cc([C@@H](O)CNCc3ccccc3)ccc2O1.Cc1cc(CCCCOCCCCCCBr)cc(NC(N)=O)c1>>Cc1cc(CCCCOCCCCCCN(Cc2ccccc2)C[C@H](O)c2ccc3c(c2)COC(C)(C)O3)cc(NC(N)=O)c1 -US07501406B2,1,COC(=O)c1ccc(CBr)c(F)c1.O=C1NCCC(F)(F)C[C@H]1NS(=O)(=O)c1ccc(Cl)cc1>>COC(=O)c1ccc(CN([C@@H]2CC(F)(F)CCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)c(F)c1 -US20140121377A1,10,CC(=O)c1ccc(-n2cncn2)nc1.O=C1CCC(=O)N1Br>>O=C(CBr)c1ccc(-n2cncn2)nc1 -US20060069123A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCOC(=O)C(C1CCN(C(=O)OC(C)(C)C)CC1)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1>>CCOC(=O)C(C1CCN(C(=O)OC(C)(C)C)CC1)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1 -US20110281862A1,7,O=[N+]([O-])C=Cc1ccc2c(c1)c1cc(Cl)cnc1n2S(=O)(=O)c1ccccc1>>O=[N+]([O-])CCc1ccc2c(c1)c1cc(Cl)cnc1n2S(=O)(=O)c1ccccc1 -US20050215578A1,1,Clc1nc(SCc2ccccc2)ns1.OCc1cncnc1>>c1ccc(CSc2nsc(OCc3cncnc3)n2)cc1 -US20140275003A1,2,Cc1ccc(C(=O)O)cc1Br.Nc1cccc(C(F)(F)F)c1>>Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Br -US06372770B1,7,COc1ccc(Cc2nc3cc(Cl)cc(CC=O)c3o2)cc1OC1CCCC1>>COc1ccc(Cc2nc3cc(Cl)cc(CCO)c3o2)cc1OC1CCCC1 -US06211199B1,6,COc1ccc(-n2cnnn2)cc1C(=O)N1CCC(CCO)(c2ccccc2)C1>>O=C(c1cc(-n2cnnn2)ccc1O)N1CCC(CCO)(c2ccccc2)C1 -US20060100249A1,3,N#Cc1ccccc1B1OC=CC(C(=O)[O-])O1.O=c1c(Br)cc(-c2ccccn2)cn1-c1ccccn1>>N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2ccccn2)c1=O -US06001835,3,CC(C)(C)OC(=O)N1CCN(c2cccc(Cl)c2)C(=O)C1.N#Cc1ccc(Cn2cncc2C=O)cc1>>CC(C)(C)OC(=O)N1CCN(c2cccc(Cl)c2)C(=O)C1C(O)c1cncn1Cc1ccc(C#N)cc1 -US07863302B2,3,CCOC(=O)c1sc(Br)nc1C(C)C.Cc1cc(O)ccc1B1OC(C)(C)C(C)(C)O1>>CCOC(=O)c1sc(-c2ccc(O)cc2C)nc1C(C)C -US20080167307A1,7,CCCCCCCNC(=O)Cc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1>>CCCCCCCNCCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1 -US06214873B1,3,BrCCCCc1ccccc1.CC(=O)NC(CCc1ccc(C=O)cc1)(CO[Si](C)(C)C(C)(C)C)CO[Si](C)(C)C(C)(C)C>>CC(=O)NC(CCc1ccc(C(O)CCCCc2ccccc2)cc1)(CO[Si](C)(C)C(C)(C)C)CO[Si](C)(C)C(C)(C)C -US20090181963A1,2,CCn1nnc2c(N3CCOC[C@@H]3C)nc(-c3ccc(N)cc3)nc21.O=C=Nc1cccs1>>CCn1nnc2c(N3CCOC[C@@H]3C)nc(-c3ccc(NC(=O)Nc4cccs4)cc3)nc21 -US20120178755A1,2,CCCCOC(=O)c1nc(C#N)c2ccc(Oc3c(C)cc(Cl)cc3C)cc2c1O.NCC(=O)O>>Cc1cc(Cl)cc(C)c1Oc1ccc2c(C#N)nc(C(=O)NCC(=O)O)c(O)c2c1 -US06204293B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC1(c2ccccc2)CCNCC1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccccc2)CC1 -US20150238492A1,8,CSCCC(CC#N)n1cc(-c2ncnc3[nH]ccc23)cn1.OO>>CS(=O)CCC(CC#N)n1cc(-c2ncnc3[nH]ccc23)cn1 -US20130216498A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(Cl)nc(-c3cnc4ccc(F)cn34)n2)C1.CN1CCNCC1>>CN1CCN(c2cc(N[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)nc(-c3cnc4ccc(F)cn34)n2)CC1 -US20100190997A1,1,N#Cc1ccc(CBr)cc1.c1nc[nH]n1>>N#Cc1ccc(Cn2cncn2)cc1 -US20020119995A1,2,CCOC(=O)C(C(=O)OCC)=C1NC(C)=C(S(N)(=O)=O)S1.Nc1ccc(-c2ccccn2)cc1>>CCOC(=O)C(C(=O)Nc1ccc(-c2ccccn2)cc1)=C1NC(C)=C(S(N)(=O)=O)S1 -US20130095193A1,8,CC(C)(C)OC(=O)NC(CF)c1ccc(CO)cc1>>CC(C)(C)OC(=O)NC(CF)c1ccc(C=O)cc1 -US20040048903A1,6,COC(=O)c1cccc(-c2ccc(CNC(=O)c3cccnc3Oc3ccc(F)cc3)cc2)c1>>O=C(O)c1cccc(-c2ccc(CNC(=O)c3cccnc3Oc3ccc(F)cc3)cc2)c1 -US20080312234A1,2,CC(C)(C)c1ccc(C=CC(=O)O)cn1.CS(=O)(=O)Nc1ccc(CN)cc1F>>CC(C)(C)c1ccc(C=CC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)cn1 -US09040526B2,2,C=CCC(CC(=O)NCc1cc(C(F)(F)F)ccc1O[Si](C(C)C)(C(C)C)C(C)C)(C(=O)[O-])C(C)C>>C=CCC1(C(C)C)CC(=O)N(Cc2cc(C(F)(F)F)ccc2O[Si](C(C)C)(C(C)C)C(C)C)C1=O -US20030166658A1,1,NNc1nc2ccccc2s1.O=C(c1ccccn1)C1CCCCC1>>c1ccc(C(=NNc2nc3ccccc3s2)C2CCCCC2)nc1 -US20120295884A1,6,COCCN(C)Cc1cc(Cl)c(F)c(CNC(=O)OC(C)(C)C)c1>>COCCN(C)Cc1cc(Cl)c(F)c(CN)c1 -US04866091,1,CC(=O)c1ccc([N+](=O)[O-])c(Cl)c1.Oc1cccc(Cl)c1>>CC(=O)c1ccc([N+](=O)[O-])c(Oc2cccc(Cl)c2)c1 -US20130345123A1,2,COC(=O)[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)[C@H](CC[C@H](Cc3ccccc3)C(=O)O)Cc3ccccc3)C(=O)N21.N[C@H]1CCC=C[C@H]2CCCCN2C1=O>>COC(=O)[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)[C@H](CC[C@H](Cc3ccccc3)C(=O)N[C@H]3CCC=C[C@H]4CCCCN4C3=O)Cc3ccccc3)C(=O)N21 -US08759344B2,6,COC(=O)c1cc(C(=O)c2nc(Br)c3ccccn23)ccc1N>>Nc1ccc(C(=O)c2nc(Br)c3ccccn23)cc1C(=O)O -US08022248B2,7,O=Cc1ccc(F)cc1OCc1ccccc1>>OCc1ccc(F)cc1OCc1ccccc1 -US04931474,8,ClCCCSCc1ccccc1.OO>>O=S(CCCCl)Cc1ccccc1 -US05726126,4,Nc1ccc(Cl)cc1F.O=C1OC(=O)C2=C1CCCC2>>O=C1C2=C(CCCC2)C(=O)N1c1ccc(Cl)cc1F -US20150183763A1,2,C[C@@H](OCc1cccc(-c2cc(N)nn2-c2ccc(F)cc2)c1)C(F)(F)F.O=C1C[C@H](C(=O)O)CN1>>C[C@@H](OCc1cccc(-c2cc(NC(=O)[C@@H]3CNC(=O)C3)nn2-c2ccc(F)cc2)c1)C(F)(F)F -US04065500,1,CN(C)C.COc1ccc(CCl)cc1[N+](=O)[O-]>>COc1ccc(C[N+](C)(C)C)cc1[N+](=O)[O-] -US20150087825A1,5,CCOC(=O)CC(=O)c1cc(Br)ccc1F.OCCO>>CCOC(=O)CC1(c2cc(Br)ccc2F)OCCO1 -US20110312975A1,1,CC[C@@H](C)N.Nc1ncc(Cl)c(-n2cccn2)c1F>>CC[C@@H](C)Nc1c(N)ncc(Cl)c1-n1cccn1 -US09000184B2,3,CC1(C)OB(c2cc(Cl)cc(C#N)c2)OC1(C)C.COC1CCC2(CCc3ccc(Br)cc3C23N=C(C)C(N)=N3)CC1>>COC1CCC2(CCc3ccc(-c4cc(Cl)cc(C#N)c4)cc3C23N=C(C)C(N)=N3)CC1 -US07705004B2,1,Cc1ccc(S(=O)(=O)n2ccc3c(Cl)nc(Cl)nc32)cc1.Cn1ncc2cc(N)ccc21>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4ccc5c(cnn5C)c4)nc(Cl)nc32)cc1 -US20120115869A1,1,CCC(=O)Nc1cc(F)cc(C#N)c1.FC(F)(F)Oc1cc(CBr)ccc1Cl>>CCC(=O)N(Cc1ccc(Cl)c(OC(F)(F)F)c1)c1cc(F)cc(C#N)c1 -US20090156575A1,2,CC1(C)C=Cc2cccc(CN3CCC4(CCNCC4)CC3)c2O1.Nc1nnccc1C(=O)O>>CC1(C)C=Cc2cccc(CN3CCC4(CC3)CCN(C(=O)c3ccnnc3N)CC4)c2O1 -US20140163025A1,1,C1CCNCC1.COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(C=O)cc5C#N)ccc(F)c43)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(CN6CCCCC6)cc5C#N)ccc(F)c43)ccc21 -US04885367,2,CCS(=O)(=O)Cl.Nc1ccccc1SC1CCCCC1>>CCS(=O)(=O)Nc1ccccc1SC1CCCCC1 -US20120035214A1,6,COC[C@H](C)COCc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2c2ccc(-c3ccccc3CCNC(=O)OCc3ccccc3)cc2C)cc1>>COC[C@H](C)COCc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2c2ccc(-c3ccccc3CCN)cc2C)cc1 -US20060160832A1,2,COc1cc2c(Oc3ccc(N)cc3)ccnc2cc1C#N.O=C=Nc1ccc(F)cc1>>COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4)cc3)ccnc2cc1C#N -US20150119362A1,7,COC(=O)Cc1ccc(Cc2cc(-c3cccc(Cl)c3)nc(C(F)(F)F)c2)cc1>>OCCc1ccc(Cc2cc(-c3cccc(Cl)c3)nc(C(F)(F)F)c2)cc1 -US05834476,7,CC(=O)Nc1ccc(C)c2c1C(=O)CCN2CC#N>>CC(=O)Nc1ccc(C)c2c1C(=O)CCN2CCN -US20130210880A1,7,Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccccc2)NC3=O)c1>>Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccccc2)NC3)c1 -US20140163025A1,1,CC(C)(O)Cn1cc(-c2c(F)cc(B(O)O)cc2F)cn1.COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(O)ccc(F)c43)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5cc(F)c(-c6cnn(CC(C)(C)O)c6)c(F)c5)ccc(F)c43)ccc21 -US20090247507A1,1,CC(C)(C)OC(=O)N1CCNCC1.COc1ccc(C=O)cn1>>COc1ccc(CN2CCN(C(=O)OC(C)(C)C)CC2)cn1 -US20140179672A1,6,CC(=O)Nc1cccc(C(CNC(=O)OC(C)(C)C)NC(=O)c2c(C)nc3c(OCc4c(F)cccc4F)cc(C)cn23)c1>>CC(=O)Nc1cccc(C(CN)NC(=O)c2c(C)nc3c(OCc4c(F)cccc4F)cc(C)cn23)c1 -US20050187247A1,1,Cn1ccnc1Sc1ccc(N)cc1Cl.N#Cc1cnc2cc(N3CCC(N4CCCC4)CC3)c([N+](=O)[O-])cc2c1Cl>>Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(N4CCC(N5CCCC5)CC4)c([N+](=O)[O-])cc23)cc1Cl -US20150210682A1,1,COc1ccc(CC(=O)C(C)C)cc1OC.[NH4+]>>COc1ccc(CC(N)C(C)C)cc1OC -US08592452B2,1,C[C@@H]1NCC[C@@H]1C(C)(C)O.N#Cc1cc(F)c(F)cc1F>>C[C@H]1[C@@H](C(C)(C)O)CCN1c1cc(F)c(C#N)cc1F -US20070149508A1,10,COc1ccc(Cl)c(C)c1.O=C1CCC(=O)N1Br>>COc1ccc(Cl)c(CBr)c1 -US07407977B2,2,Nc1nc2c(s1)Cc1cc(Cl)ccc1-2.O=C(Cl)c1ccncc1>>O=C(Nc1nc2c(s1)Cc1cc(Cl)ccc1-2)c1ccncc1 -US04052191,2,CCCCCc1nnc(N=C=O)s1.CCNCC=O>>CCCCCc1nnc(NC(=O)N(CC)CC=O)s1 -US08173650B2,1,Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CBr)n(C)c2n1.NCC1(O)CCCCC1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CNCC3(O)CCCCC3)n(C)c2n1 -US20130315874A1,4,C#CCCCc1c[nH]c(N)n1.[N-]=[N+]=NCCCc1ccccc1>>Nc1nc(CCCc2cn(CCCc3ccccc3)nn2)c[nH]1 -US06605626B2,2,CC(C)(C)c1ccc(C(=O)Cl)cc1.COc1ccc(C(=O)Nc2ccccc2O)cc1>>COc1ccc(C(=O)Nc2ccccc2OC(=O)c2ccc(C(C)(C)C)cc2)cc1 -US08962674B2,7,O=C(/C=C/c1ccc(O)cc1)CC(=O)/C=C/c1cc(OCc2ccccc2)ccc1[N+](=O)[O-]>>Nc1ccc(OCc2ccccc2)cc1/C=C/C(=O)CC(=O)/C=C/c1ccc(O)cc1 -US20040014968A1,6,COC(=O)C(CC1CCCC1)c1ccc(S(C)(=O)=O)c(C(F)(F)F)c1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1C(F)(F)F -US20100035865A1,6,CC(C)S(=O)(=O)NC1COCCC12OCCO2>>CC(C)S(=O)(=O)NC1COCCC1=O -US09029399B2,1,FC(F)(F)c1csc2ccc(Br)cc12.O=C1NCCN1c1cnccc1C1CC1>>O=C1N(c2ccc3scc(C(F)(F)F)c3c2)CCN1c1cnccc1C1CC1 -US20090005363A1,1,CCOC(=O)c1cnc(Cl)c(C)c1.Cc1ccc(N)cn1>>CCOC(=O)c1cnc(Nc2ccc(C)nc2)c(C)c1 -US20120230951A1,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Clc1ncc(Br)cn1>>C=C(OCC)c1cnc(Cl)nc1 -US07795250B2,1,C=[N+]=[N-].O=C(O)C=Cc1ccc(Cl)c([N+](=O)[O-])c1>>COC(=O)/C=C/c1ccc(Cl)c([N+](=O)[O-])c1 -US20080261941A1,6,Cc1cccnc1Oc1cccc(C=C2CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1cccnc1Oc1cccc(C=C2CCNCC2)c1 -US06951879B2,1,BrCCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1.CNCCO>>CN(CCO)CCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1 -US20130029980A1,1,BrCc1ccccc1.[N-]=[N+]=NCC(O)Cc1ccccc1>>[N-]=[N+]=NCC(Cc1ccccc1)OCc1ccccc1 -US20070049632A1,1,CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccc(F)cc3F)c(=O)c12.COc1ccc(CBr)cc1>>COc1ccc(Cn2c3c(c(=O)n2-c2ccc(F)cc2F)[C@H]2CC[C@]3(C)C2(C)C)cc1 -US04255432,1,CI.OCCc1c[nH]c2ccccc12>>Cn1cc(CCO)c2ccccc21 -US05352655,7,C=C(C)c1cccc(C(C)(C)N)c1>>CC(C)c1cccc(C(C)(C)N)c1 -US20050267133A1,1,NNc1ncnc2c1cnn2-c1ccccc1.O=Cc1cccc(OCCO)c1>>OCCOc1cccc(C=NNc2ncnc3c2cnn3-c2ccccc2)c1 -US05714506,9,COc1ccc(C(Cc2ccccc2)NC[C@H](O)c2ccc(Cl)nc2)cc1OC>>COc1ccc(C(Cc2ccccc2)NC[C@H](O)c2cccnc2)cc1OC -US20140200225A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.N#Cc1ccc(Oc2cc(N)cc(Oc3ccc(C#N)cc3)c2)cc1>>CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc(Oc3ccc(C#N)cc3)cc(Oc3ccc(C#N)cc3)c2)CC1 -US20100016319A1,1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)ccc2O)cc1.Clc1ccnc(Cl)n1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)ccc2Oc2ccnc(Cl)n2)cc1 -US08377975B2,2,CCc1c(C(=O)O)ccc(OC)c1C.CO>>CCc1c(C(=O)OC)ccc(OC)c1C -US04411898,6,CCOC(=O)C(=NOC)c1csc(NC=O)n1>>CON=C(C(=O)O)c1csc(NC=O)n1 -US07176231B2,9,CC(=O)c1ccc2c(c1)C(=C(O)c1cnccn1)C(=O)N2C(C)=O.ClC(Cl)(Cl)Cl>>CC(=O)c1ccc2c(c1)C(=C(Cl)c1cnccn1)C(=O)N2C(C)=O -US08247403B2,7,O=C1c2ccc(F)c(Br)c2OCCN1Cc1ccccc1>>Fc1ccc2c(c1Br)OCCN(Cc1ccccc1)C2 -US20040082611A1,1,CC(C)(C)OC(=O)N1CCc2sc(C=O)cc2C1.N[C@H]1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1>>CC(C)(C)OC(=O)N1CCc2sc(CN[C@H]3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)C3)cc2C1 -US20140155419A1,2,COc1ccc(CC(=O)O)cc1C.Cc1cc(Cl)ccc1C(N)c1ccccc1>>COc1ccc(CC(=O)NC(c2ccccc2)c2ccc(Cl)cc2C)cc1C -US20120058999A1,2,CCOC(=O)C1NCCn2cccc21.Cc1cccc(Cl)c1S(=O)(=O)Cl>>CCOC(=O)C1c2cccn2CCN1S(=O)(=O)c1c(C)cccc1Cl -US20120004164A1,2,CNC.Cc1nc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C(=O)O>>Cc1nc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C(=O)N(C)C -US06030984,2,COCCNc1cc(C)ns1.O=C(O)c1cc(-c2ccc(OCc3ccccc3)cc2)c(=O)n2ccc3ccsc3c12>>COCCN(C(=O)c1cc(-c2ccc(OCc3ccccc3)cc2)c(=O)n2ccc3ccsc3c12)c1cc(C)ns1 -US03960892,3,COc1cccc(C=O)c1C(=O)O.O=C1CSC(=S)N1>>COc1cccc(C=C2SC(=S)NC2=O)c1C(=O)O -US20040087798A1,7,O=C(Nc1cccc(-n2ccnc2)c1)C1=Cc2ccccc2OCC1>>O=C(Nc1cccc(-n2ccnc2)c1)C1CCOc2ccccc2C1 -US06288091B1,2,CC(=O)c1ccc(N)cc1.CC(C)(C)OC(=O)N(CC(=O)O)Cc1ccccc1>>CC(=O)c1ccc(NC(=O)CN(Cc2ccccc2)C(=O)OC(C)(C)C)cc1 -US20130165426A1,9,COC(=O)c1nc(Cl)c2nc(-c3ccc(OC)cc3)n(CCCN3CCCCC3)c2n1>>COC(=O)c1ncc2nc(-c3ccc(OC)cc3)n(CCCN3CCCCC3)c2n1 -US20080032998A1,2,Cc1ccccc1C1=CCNCC1.O=C(O)c1cc2ncc(Cl)cn2n1>>Cc1ccccc1C1=CCN(C(=O)c2cc3ncc(Cl)cn3n2)CC1 -US08669255B2,6,COC(=O)CNC[C@@H]1C[C@@H](Oc2cnc(C3CC3)cn2)CN1C(=O)OC(C)(C)C>>COC(=O)CNC[C@@H]1C[C@@H](Oc2cnc(C3CC3)cn2)CN1 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3sc(C(F)(F)F)cc23)cc1OC.Cc1ncc[nH]1>>COc1ccc(CNc2nc(-n3ccnc3C)nc3sc(C(F)(F)F)cc23)cc1OC -US06184379B2,6,CCN1c2cc(OC)ccc2C(C)=CC1(C)C>>CCN1c2cc(O)ccc2C(C)=CC1(C)C -US08188139B2,1,CC(C)(C)OC(=O)N1Cc2cc(F)c(I)cc2C1.OC1CCOCC1>>CC(C)(C)OC(=O)N1Cc2cc(F)c(OC3CCOCC3)cc2C1 -US08394986B2,1,BrCc1ccccc1.Oc1cc(C(F)(F)F)ccc1F>>Fc1ccc(C(F)(F)F)cc1OCc1ccccc1 -US20120289500A1,2,CC(C)(CC(=O)O)c1ccccc1.Nn1nc(S(=O)(=O)c2ccccc2)c2ccccc2c1=O>>CC(C)(CC(=O)Nn1nc(S(=O)(=O)c2ccccc2)c2ccccc2c1=O)c1ccccc1 -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.O=C=Nc1ccc(OC(F)F)cc1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)Nc3ccc(OC(F)F)cc3)CC2)nc1C(F)(F)F -US20110257208A1,1,O=Cc1ccccc1OC(F)(F)F.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>FC(F)(F)Oc1ccccc1CN1Cc2ncnc(Nc3cnc4ccccc4c3)c2C1 -US20090048258A1,3,N#Cc1ccccc1B(O)O.O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(Cl)cc(-c2ccccc2)n1>>N#Cc1ccccc1-c1cc(NC(=O)CCC(=O)c2ccc3c(c2)CCO3)nc(-c2ccccc2)c1 -US06743795B1,1,Nc1ccc2cn[nH]c2c1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>O=[N+]([O-])c1ccc(Cl)nc1Nc1ccc2cn[nH]c2c1 -US06696445B2,7,COc1ccc(CC(=O)NCCNc2cc(C)nc(Oc3c(C)cc(C)cc3C)c2C)cc1OC>>COc1ccc(CCNCCNc2cc(C)nc(Oc3c(C)cc(C)cc3C)c2C)cc1OC -US06051712,1,CC(C)(C)OC(=O)N1CCC(c2ccc(F)cc2)C(O)C1.COc1ccc(CCl)cc1>>COc1ccc(COC2CN(C(=O)OC(C)(C)C)CCC2c2ccc(F)cc2)cc1 -US06251910B1,1,CCCSc1nc(N(Cc2ccc(OC)cc2OC)C2CC2c2ccccc2)c2nnn(C3CC(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)C(O)C3O)c2n1.CI>>CCCSc1nc(N(Cc2ccc(OC)cc2OC)C2CC2c2ccccc2)c2nnn(C3CC(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)C(OC)C3O)c2n1 -US20150093655A1,1,CCN(C)C.OCCCCCCCl>>CC[N+](C)(C)CCCCCCO -US05965555,1,C#CC(C)(O)CCCCCl.Cn1c(=O)[nH]c(=O)c2[nH]cnc21>>C#CC(C)(O)CCCCn1cnc2c1c(=O)[nH]c(=O)n2C -US20100120770A1,2,COCCOC(=O)Cl.Cc1ccnc(Nc2ncc(Sc3ccnc(C(=O)NCC4(c5ccc(Cl)c(Cl)c5)CCNCC4)c3F)s2)c1>>COCCOC(=O)N1CCC(CNC(=O)c2nccc(Sc3cnc(Nc4cc(C)ccn4)s3)c2F)(c2ccc(Cl)c(Cl)c2)CC1 -US05326840,2,C=C(C)C(=O)OC(=O)C(=C)C.Nc1cccc(O)c1>>C=C(C)C(=O)Nc1cccc(O)c1 -US05726313,2,CNCC(OCCN1CCC(NC(C)=O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1.O=C(Cl)OCc1ccccc1>>CC(=O)NC1(c2ccccc2)CCN(CCOC(CN(C)C(=O)OCc2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 -US07999006B2,2,NCCO.O=C(O)C1CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1>>O=C(NCCO)C1CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US20090264405A1,2,Cc1ccccc1OCC(=O)O.Nc1ccc(-c2nc3cc(Cl)ccc3o2)cn1>>Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cn1 -US06974802B2,1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.COc1ccc(COC(=O)C2CCC(O)CC2)cc1>>COc1ccc(COC(=O)C2CCC(OC(=O)[C@@H](NC(=O)OCc3ccccc3)C(C)C)CC2)cc1 -US20100041696A1,6,CC(C)(C)OC(=O)N1CCc2cc(C(=O)Nc3cnn(Cc4ccc(Cl)c(Cl)c4)c3)ccc2C1>>O=C(Nc1cnn(Cc2ccc(Cl)c(Cl)c2)c1)c1ccc2c(c1)CCNC2 -US06727264B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CCCC(O)c3ccccc3)CC2)c1.Cc1onc(-c2ccccc2Cl)c1C(=O)Cl>>Cc1onc(-c2ccccc2Cl)c1C(=O)OC(CCCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)c1ccccc1 -US20110178060A1,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(=O)O)CC1.CN(C(=O)N(C)[C@@H]1CNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN(C(=O)N(C)[C@@H]1CN(C(=O)[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US08288549B2,1,N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1N[C@@H](Cc1ccc(O)cc1)C(=O)O -US04226775,2,CC(C)(C)OC(=O)[C@@H]1CCCN1.O=C(CC(C(=O)O)c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)C(CC(=O)c1ccccc1)c1ccccc1 -US20060135525A1,2,CCOC(=O)Cl.CCOc1cccc(Cn2ncc3c(N4CCN(C(=O)c5ccc(N(CCN(C)C)C(=O)CCNC)cc5)CC4)ncnc32)c1>>CCOC(=O)N(C)CCC(=O)N(CCN(C)C)c1ccc(C(=O)N2CCN(c3ncnc4c3cnn4Cc3cccc(OCC)c3)CC2)cc1 -US06867218B2,7,CCOC(=O)/C=C(\C)c1ccc(-c2ccccc2C)cc1>>C/C(=C\CO)c1ccc(-c2ccccc2C)cc1 -US20090264499A1,2,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.O=[N+]([O-])c1ccc(Br)c(S(=O)(=O)Cl)c1>>CC(C)(C)OC(=O)N1CC[C@@H](NS(=O)(=O)c2cc([N+](=O)[O-])ccc2Br)C1 -US20130079328A1,2,Cn1cc(-c2ccc(CN)cc2F)ccc1=O.O=C(O)c1ccc(-c2cnccn2)cc1>>Cn1cc(-c2ccc(CNC(=O)c3ccc(-c4cnccn4)cc3)cc2F)ccc1=O -US20080312226A1,6,CC(C)(C)OC(=O)N1CCN(c2nc(-c3cccc(C(F)(F)F)c3)cs2)CC1>>FC(F)(F)c1cccc(-c2csc(N3CCNCC3)n2)c1 -US20080280950A1,2,O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.OCC(F)(F)C(F)F>>O=S(=O)(OCC(F)(F)C(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F -US20090149469A1,1,Clc1nccc(-c2c[nH]nc2-c2cccc(OCc3ccccc3)c2)n1.Nc1ccc(C(=O)O)cc1>>O=C(O)c1ccc(Nc2nccc(-c3c[nH]nc3-c3cccc(OCc4ccccc4)c3)n2)cc1 -US20030149027A1,6,CC(C)(C)OC(=O)NCc1ccc(N2C(=O)C(CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(O)cc3)c3ccccc32)cc1>>NCc1ccc(N2C(=O)C(CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(O)cc3)c3ccccc32)cc1 -US20060161002A1,1,Nc1cccc(F)c1.O=C1CCCc2c1[nH]c1ccc(Br)cc21>>Fc1cccc(NC2CCCc3c2[nH]c2ccc(Br)cc32)c1 -US20070270437A1,7,COC(=O)c1sc(Nc2cc(OCc3ccc(OC)cc3)ccc2[N+](=O)[O-])cc1O[C@H](C)c1ccccc1Cl>>COC(=O)c1sc(Nc2cc(OCc3ccc(OC)cc3)ccc2N)cc1O[C@H](C)c1ccccc1Cl -US20090186874A1,9,CCOC(=O)C(=O)N1CC[C@@H](C(=O)N(C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](c2ccc(F)cc2C)C1.N>>Cc1cc(F)ccc1[C@@H]1CN(C(=O)C(N)=O)CC[C@H]1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US07951954B2,2,COc1ccccc1CN.O=C(O)Cc1cccc(CC(=O)O)c1>>COc1ccccc1CNC(=O)Cc1cccc(CC(=O)O)c1 -US20050261290A1,6,CC(C)(C)OC(=O)N1CCCC(C(=O)NC2C3CC4CC(C3)CC2C4)C1>>O=C(NC1C2CC3CC(C2)CC1C3)C1CCCNC1 -US07572801B2,1,N=C(COCCc1cc(F)ccc1F)NC(=O)c1cc(Cl)cnc1Cl>>O=c1[nH]c(COCCc2cc(F)ccc2F)nc2ncc(Cl)cc12 -US20120277265A1,8,COc1ccc2cccnc2c1OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2ccc[n+]([O-])c2c1OCc1ccccc1 -US20100035918A1,1,BrCc1ccc2nsnc2c1.Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)[nH]c2=O)c1>>Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)n(Cc3ccc4nsnc4c3)c2=O)c1 -US08063085B2,8,CC(O)c1c(F)cc(I)cc1F>>CC(=O)c1c(F)cc(I)cc1F -US04282251,3,C=O.CC(=O)c1ccc(C)cc1.CNCc1cccc2ccccc12>>Cc1ccc(C(=O)CCN(C)Cc2cccc3ccccc23)cc1 -US20010031786A1,7,Cc1nc2c(o1)CCc1ccccc1C2OCC(=O)OC(C)(C)C>>Cc1nc2c(o1)CCc1ccccc1C2OCCO -US20120121508A1,1,COC(=O)C1(N)CCCC1.O=C(CBr)c1cc(F)cc(F)c1>>COC(=O)C1(NCC(=O)c2cc(F)cc(F)c2)CCCC1 -US20050026925A1,1,CI.Cc1nc2c(cc1O)C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N21>>COc1cc2c(nc1C)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C -US08841467B2,1,CCO.CCOC(=O)C(=O)C1=COCC1>>CCOC(=O)C(=O)C1CCOC1OCC -US07504412B2,3,COC(=O)c1ccc(B(O)O)cc1.Cc1ccc(Br)nc1>>COC(=O)c1ccc(-c2ccc(C)cn2)cc1 -US20080188528A1,1,CC(C)(C)CI.COC(=O)c1ccc[nH]c1=O>>COC(=O)c1cccn(CC(C)(C)C)c1=O -US07846956B2,1,CCI.Cn1c(CO)cnc1S>>CCSc1ncc(CO)n1C -US20070293521A1,1,Fc1cnc(Cl)nc1NCc1csc2ccc(Cl)cc12.Nc1ccc2c(c1)OCCO2>>Fc1cnc(Nc2ccc3c(c2)OCCO3)nc1NCc1csc2ccc(Cl)cc12 -US07728029B2,6,CCOC(=O)c1cnn(C2CC2)c1Cl>>O=C(O)c1cnn(C2CC2)c1Cl -US20130005707A1,7,CNc1ccc([N+](=O)[O-])cn1>>CNc1ccc(N)cn1 -US06534434B2,3,C1=CCCC=C1.C=CC=O>>O=C[C@@H]1CC2C=CC1CC2 -US08785481B2,7,COc1ccc(NCC(C)(C)C)c([N+](=O)[O-])c1>>COc1ccc(NCC(C)(C)C)c(N)c1 -US20070259851A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1cccnc1N>>CC(C)(C)OC(=O)N1CCC(Nc2cccnc2N)CC1 -US20150164974A1,6,C[C@@H](C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C)N(C)C(=O)OC(C)(C)C>>C[C@@H](C(=O)N[C@H](C(=O)N1C[C@@H](N)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C)N(C)C(=O)OC(C)(C)C -US20150191439A1,1,NC12CC3CC(CC(C3)C1)C2.O=Cc1ccc(-c2ccccc2)cc1>>c1ccc(-c2ccc(CNC34CC5CC(CC(C5)C3)C4)cc2)cc1 -US20130005721A1,10,CCOC(=O)c1nc2cc(C)ccn2c1-c1ccc(F)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc2cc(CBr)ccn2c1-c1ccc(F)cc1 -US20140364433A1,6,C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-c2ncccn2)[C@@H]1CN1C(=O)c2ccccc2C1=O>>C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-c2ncccn2)[C@@H]1CN -US08039493B2,1,CC(C)S(=O)(=O)NCc1cccc(-c2cccc(S(C)(=O)=O)c2)c1.Fc1ccccc1CBr>>CC(C)S(=O)(=O)N(Cc1cccc(-c2cccc(S(C)(=O)=O)c2)c1)Cc1ccccc1F -US08367843B2,2,COc1c(SC)cc(C(=O)Cl)cc1C(F)(F)F.c1ccc2c(c1)NCS2>>COc1c(SC)cc(C(=O)N2CSc3ccccc32)cc1C(F)(F)F -US20120129870A1,2,COC(=O)[C@@H](N)CO.O=C(O)C(c1ccccc1)N1CCN(c2ccc([N+](=O)[O-])cc2F)CC1>>COC(=O)C(CO)NC(=O)C(c1ccccc1)N1CCN(c2ccc([N+](=O)[O-])cc2F)CC1 -US20040248941A1,1,CC(C)OC(=O)OC(C)I.Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1>>Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2n1C(C)OC(=O)OC(C)C -US05506256,8,O=C(COc1ccccc1)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(O)COc1ccccc1>>O=C(COc1ccccc1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)COc1ccccc1 -US20070082908A1,6,COC(OC)c1nn(S(=O)(=O)N(C)C)c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)c1Cc1ccccc1Cl>>CN(C)S(=O)(=O)n1nc(C=O)c(Cc2ccccc2Cl)c1N1CCC[C@@H](NC(=O)OC(C)(C)C)C1 -US07989634B2,6,CC(C)(C)OC(=O)NCC(=O)N(C1CCCCC1)[C@H]1CCN(C(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)NCC(=O)N(C1CCCCC1)[C@H]1CCNC1 -US20100216746A1,6,CCOC(=O)c1[nH]c2ccccc2c1Br>>O=C(O)c1[nH]c2ccccc2c1Br -US20020128214A1,1,CCCCCCCCCCCCCCCCBr.OC[C@H]1CCO[C@H](c2ccccc2)O1>>CCCCCCCCCCCCCCCCOC[C@H]1CCO[C@H](c2ccccc2)O1 -US20060276464A1,2,CCCc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)Cl.NC1CCOCC1>>CCCc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)NC1CCOCC1 -US20130085161A1,7,Cc1ccc([N+](=O)[O-])c(N2CCC(n3c(=N)n(Cc4ccccc4Cl)c4ccc(F)cc43)CC2)n1>>Cc1ccc(N)c(N2CCC(n3c(=N)n(Cc4ccccc4Cl)c4ccc(F)cc43)CC2)n1 -US06770662B2,8,COc1cc(C)c(C(=O)c2c(Cl)cncc2OC)c(OC)c1OC.O=C(OO)c1cccc(Cl)c1>>COc1cc(C)c(C(=O)c2c(Cl)c[n+]([O-])cc2OC)c(OC)c1OC -US07253198B2,2,CC(=O)OC(C)=O.COC(=O)c1cc(N)cc(N2CCCC2=O)c1>>COC(=O)c1cc(NC(C)=O)cc(N2CCCC2=O)c1 -US04017613,1,CCOP(OCC)OCC.O=CC(Cl)(Cl)C=C(Cl)Cl>>CCOP(=O)(OC=C(Cl)C=C(Cl)Cl)OCC -US20070082912A1,4,CC(=O)CCC(=O)c1ccccc1OCc1ccc(F)cc1.Nc1cccc(S(N)(=O)=O)c1>>Cc1ccc(-c2ccccc2OCc2ccc(F)cc2)n1-c1cccc(S(N)(=O)=O)c1 -US05935990,1,Cc1c(CO)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1.Oc1ccc(Cl)cc1>>Cc1c(COc2ccc(Cl)cc2)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 -US07378417B2,2,CC(C)(CO)NS(=O)(=O)c1cccc(N)c1.CCCc1cc(-c2ccc(Cl)cc2)nc2c(C(=O)O)cnn12>>CCCc1cc(-c2ccc(Cl)cc2)nc2c(C(=O)Nc3cccc(S(=O)(=O)NC(C)(C)CO)c3)cnn12 -US20080064715A1,2,NC(c1ccccc1)c1cc2ccncc2[nH]1.O=C(O)c1ccccc1>>O=C(NC(c1ccccc1)c1cc2ccncc2[nH]1)c1ccccc1 -US20140192305A1,1,COc1cc(C=O)ccc1O.OCCCCCCCCCCCBr>>COc1cc(C=O)ccc1OCCCCCCCCCCCO -US08115016B2,2,CC(C)(C)C(=O)Cl.CC1(C(=O)O)CC(Cc2ccc(-c3ccccc3)cc2)NC1=O>>CC(C)(C)C(=O)N1C(=O)[C@@](C)(C(=O)O)C[C@H]1Cc1ccc(-c2ccccc2)cc1 -US08115016B2,2,CC(C)(C)C(=O)Cl.CC1(C(=O)O)CC(Cc2ccc(-c3ccccc3)cc2)NC1=O>>CC(C)(C)C(=O)N1C(=O)[C@](C)(C(=O)O)C[C@H]1Cc1ccc(-c2ccccc2)cc1 -US20090099176A1,2,NC1Cc2ccccc2NC1=O.O=C(O)c1cc2cnc(Cl)cc2[nH]1>>O=C(NC1Cc2ccccc2NC1=O)c1cc2cnc(Cl)cc2[nH]1 -US20050096380A1,6,CCOC(=O)/C=C(C)/C=C/C(F)=C(/CC)c1cc2c(c(Cl)c1OCC)C(C)(C)CC=C2C(C)C>>CCOc1c(/C(CC)=C(F)\C=C\C(C)=C\C(=O)O)cc2c(c1Cl)C(C)(C)CC=C2C(C)C -US20090318690A1,1,CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(O)ccc23)CC1.ClCc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(OCc4ccc(Cl)c(Cl)c4)ccc23)CC1 -US20050267150A1,2,CC(=S)C(C(=O)O)C(C)C.C[C@H](N)C(=O)C1(N)N=C(c2ccccc2)c2ccccc2N(C)C1=O>>CC(=S)C(C(=O)N[C@@H](C)C(=O)C1(N)N=C(c2ccccc2)c2ccccc2N(C)C1=O)C(C)C -US20050137398A1,1,O=[N+]([O-])c1ccc(I)cc1.OC1CN2CCC1CC2>>O=[N+]([O-])c1ccc(OC2CN3CCC2CC3)cc1 -US20130296312A1,1,CN(c1ccccc1CNc1cccn2nc(Cl)nc12)S(C)(=O)=O.CN1CCN(c2cccc(N)c2)CC1>>CN1CCN(c2cccc(Nc3nc4c(NCc5ccccc5N(C)S(C)(=O)=O)cccn4n3)c2)CC1 -US08969587B2,1,CC(C)(C)c1cc(NC(=O)Nc2cccc(S)c2)no1.COc1ccc2c(Cl)ncnc2c1>>COc1ccc2c(Sc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)ncnc2c1 -US07879844B2,9,NC(=O)C12CC3CC(C1)C(n1c(=O)[nH]c4cnc5[nH]ccc5c41)C(C3)C2>>N#CC12CC3CC(C1)C(n1c(=O)[nH]c4cnc5[nH]ccc5c41)C(C3)C2 -US08183262B2,1,Brc1c[nH]cn1.FC(F)c1cc(-c2ccc(C(F)(F)F)cc2)nc(Cl)n1>>FC(F)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-n2cnc(Br)c2)n1 -US09000025B2,1,CCCn1cc(Br)cn1.CCOC(=O)c1cccc(Sc2c(C)[nH]c3cc(Cl)c(F)cc23)c1>>CCCn1cc(-n2c(C)c(Sc3cccc(C(=O)OCC)c3)c3cc(F)c(Cl)cc32)cn1 -US20050038035A1,6,CC(C)(C)OC(=O)N(CCc1ccccn1)c1ccc(NC(=O)C2=C(c3ccc(F)cc3)CCCC2)cc1>>O=C(Nc1ccc(NCCc2ccccn2)cc1)C1=C(c2ccc(F)cc2)CCCC1 -US20060211739A1,1,Cc1ccncc1CCl.Clc1ccc(-c2nnn[nH]2)cc1Cl>>Cc1ccncc1Cn1nnnc1-c1ccc(Cl)c(Cl)c1 -US03962255,2,CC1(C)CNC(=O)CC(C)(C)N1.O=C=Nc1ccc(Cl)cc1>>CC1(C)CC(=O)N(C(=O)Nc2ccc(Cl)cc2)CC(C)(C)N1 -US20040180925A1,1,CC(C)(N)CN.N#Cc1ccc(Cl)nc1>>CC(C)(N)CNc1ccc(C#N)cn1 -US20040030105A1,6,CC(=O)SCP(c1ccccc1)c1ccccc1>>SCP(c1ccccc1)c1ccccc1 -US08304557B2,2,Cn1cccc1C(=O)O.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>Cn1cccc1C(=O)Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1 -US20040122057A1,2,CCOC(C(=O)O)c1c(F)cc(OC)cc1F.N#Cc1ccc(CN)c(Oc2ccccc2)c1>>CCOC(C(=O)NCc1ccc(C#N)cc1Oc1ccccc1)c1c(F)cc(OC)cc1F -US20050282816A1,1,CC1(c2ccc(Br)cc2)CCOCC1.CN1CCN(c2nccnc2CC2CCCNC2=O)CC1>>CN1CCN(c2nccnc2CC2CCCN(c3ccc(C4(C)CCOCC4)cc3)C2=O)CC1 -US20090054440A1,1,C1CNCCN1.Cc1nc(CCl)cs1>>Cc1nc(CN2CCNCC2)cs1 -US20150191495A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(Br)c(I)cn2)cc1>>C=Cc1cnc(N(Cc2ccc(OC)cc2)Cc2ccc(OC)cc2)cc1Br -US08022062B2,1,Cn1ccnc1-c1ccc(CN)cc1.O=C(N1CCc2ccc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F>>Cn1ccnc1-c1ccc(CNc2c(Cl)ccc3c2CCN(C(=O)C(F)(F)F)CC3)cc1 -US20060069110A1,3,CNc1nc(Cl)nc(OC)n1.OB(O)c1ccccc1>>CNc1nc(OC)nc(-c2ccccc2)n1 -US07217723B2,1,CNCc1ccccc1.O=C(CCl)c1ccc(F)cc1>>CN(CC(=O)c1ccc(F)cc1)Cc1ccccc1 -US20110136902A1,6,C=C[C@@H](C)C[C@H]1O[C@@H]1[C@H](C)[C@H](CC)O[Si](C)(C)C(C)(C)C>>C=C[C@@H](C)C[C@H]1O[C@@H]1[C@H](C)[C@@H](O)CC -US20060058287A1,3,C=C[Sn](CCCC)(CCCC)CCCC.N#Cc1ccc2nccc(Br)c2c1>>C=Cc1ccnc2ccc(C#N)cc12 -US06353000B1,7,CC(C)(C)[Si](OC[C@@H]1[C@@H](F)C[C@@H]2OC(=O)C[C@@H]21)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OC[C@@H]1[C@@H](F)C[C@@H]2OC(O)C[C@@H]21)(c1ccccc1)c1ccccc1 -US08309581B2,1,COC(=O)COc1ccc(CBr)cc1.Oc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2n1Cc1cccc(Cl)c1>>COC(=O)COc1ccc(COc2cc(Cl)ccc2-c2nc3cc(F)c(F)cc3n2Cc2cccc(Cl)c2)cc1 -US20060116368A1,2,Nc1cnc2ccccc2c1.O=C(O)C1CCN(c2cccc(-c3ccccc3)c2)CC1>>O=C(Nc1cnc2ccccc2c1)C1CCN(c2cccc(-c3ccccc3)c2)CC1 -US04000253,2,CCCCN=C=O.Oc1ccc(N=C=S)cc1>>CCCCNC(=O)Oc1ccc(N=C=S)cc1 -US06063932,7,O=C(CCl)c1ccc(-c2ccc(S(=O)(=O)C(F)F)cc2)cc1>>O=S(=O)(c1ccc(-c2ccc(C(O)CCl)cc2)cc1)C(F)F -US08173813B2,1,CN(C)CCCl.O=C1CCc2cccc(F)c2N1>>CN(C)CCN1C(=O)CCc2cccc(F)c21 -US20130096149A1,3,CN(C)C=O.Fc1ccc(Cl)cc1Br>>O=Cc1cc(Cl)cc(Br)c1F -US08293768B2,1,BrCc1ccccc1.CCOC(=O)c1sc(-n2cn[nH]c2=O)cc1C>>CCOC(=O)c1sc(-n2cnn(Cc3ccccc3)c2=O)cc1C -US20120252801A1,2,CC(C)c1ccc(N)cc1.CCN1CC(C)(C)OC(=O)C1C(C)(C)C(=O)O>>CCN1CC(C)(C)OC(=O)C1C(C)(C)C(=O)Nc1ccc(C(C)C)cc1 -US05506240,1,Cc1ccc2oc(-c3ccccc3-c3nnn[nH]3)c(Br)c2c1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1ccc2oc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)c(Br)c2c1 -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(Oc3ncns3)cc(C)c21>>Cc1cc(Oc2ncns2)cc2c1C(CC(=O)O)OB2O -US07566781B2,1,Cc1c(CCCO)nc2ccc(NC(=O)c3ccc(OCc4ccccn4)cc3)cn12.FC1(F)CCNC1>>Cc1c(CCCN2CCC(F)(F)C2)nc2ccc(NC(=O)c3ccc(OCc4ccccn4)cc3)cn12 -US04107310,2,Nc1ncc[nH]1.O=C(O)c1cnc2c(C(F)(F)F)cccc2c1O>>O=C(Nc1ncc[nH]1)c1cnc2c(C(F)(F)F)cccc2c1O -US20100105727A1,2,C=CC(=O)Cl.Nc1cccc2ncccc12>>C=CC(=O)Nc1cccc2ncccc12 -US04444775,6,COC(=O)CCCCc1ccc2cncn2c1>>O=C(O)CCCCc1ccc2cncn2c1 -US05569664,1,CCOC(=O)C1CCNCC1.COc1cccc(OC)c1CBr>>CCOC(=O)C1CCN(Cc2c(OC)cccc2OC)CC1 -US20050027121A1,7,CCOC(=O)CCc1cn(C)cn1>>Cn1cnc(CCCO)c1 -US06987114B1,1,Cc1cc(C)cc(Sc2[nH]c(=O)[nH]c(=O)c2C(C)C)c1.O=C1c2ccccc2C(=O)c2cc(CCl)ccc21>>Cc1cc(C)cc(Sc2c(C(C)C)c(=O)[nH]c(=O)n2Cc2ccc3c(c2)C(=O)c2ccccc2C3=O)c1 -US20130184257A1,2,CC(C)(C)OC(=O)N1CCC(NCCC[C@H](NC(=O)OCc2ccccc2)C(=O)O)CC1>>CC(C)(C)OC(=O)N1CCC(N2CCC[C@H](NC(=O)OCc3ccccc3)C2=O)CC1 -US20120270865A2,3,CC(C)C[Mg+].COc1ccc2oc(C=O)c(C)c2c1>>COc1ccc2oc(C(O)CC(C)C)c(C)c2c1 -US20140163017A1,1,CC(=O)c1cc(Cl)ccc1O.CN1CCN(S(=O)(=O)c2cccc(C(=O)NN)c2)CC1>>C/C(=N\NC(=O)c1cccc(S(=O)(=O)N2CCN(C)CC2)c1)c1cc(Cl)ccc1O -US06150530,4,CCOC(=O)C(=O)CBr.NC(=S)N1CCOCC1>>CCOC(=O)c1csc(N2CCOCC2)n1 -US20140107109A1,9,COc1cc(F)c(C#N)c(F)c1.N>>COc1cc(N)c(C#N)c(F)c1 -US08153658B2,6,C[C@H](c1cccc2ccccc12)N(CC1CN(C(=O)C(F)(F)F)CCC1c1ccccc1F)C(=O)OC(C)(C)C>>C[C@H](c1cccc2ccccc12)N(CC1CNCCC1c1ccccc1F)C(=O)OC(C)(C)C -US07884234B2,1,CC(C)(C)c1ccc(B(O)O)cc1.Nc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1>>CC(C)(C)c1ccc(Nc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)cc1 -US05668176,2,CCCc1cc(S(N)(=O)=O)ccc1OC(C(=O)OC)c1ccc2c(c1)OCO2.CN=C=O>>CCCc1cc(S(=O)(=O)NC(=O)NC)ccc1OC(C(=O)OC)c1ccc2c(c1)OCO2 -US08501793B2,3,CCCC[C@H](C)CC(=O)CP(=O)(OC)OC.COC(=O)CCC/C=C\C[C@@H]1[C@@H](C=O)[C@H](OC2CCCCO2)C[C@H]1Cl>>CCCC[C@H](C)CC(=O)/C=C/[C@H]1[C@H](OC2CCCCO2)C[C@@H](Cl)[C@@H]1C/C=C\CCCC(=O)OC -US06653307B2,1,C1COCCN1.O=Cc1ccc(F)c(Br)c1>>Fc1ccc(CN2CCOCC2)cc1Br -US20040225123A1,6,COc1ccc(-c2cc(Cl)c3cc(O)c(Br)cc3c2)cc1>>Oc1ccc(-c2cc(Cl)c3cc(O)c(Br)cc3c2)cc1 -US06492406B1,9,Cn1cc(-c2n[nH]c(=O)n2-c2cn(CCCBr)c3ccc(F)cc23)c2cc(F)ccc21.[C-]#N>>Cn1cc(-c2n[nH]c(=O)n2-c2cn(CCCC#N)c3ccc(F)cc23)c2cc(F)ccc21 -US20120115869A1,3,CCC(=O)N(Cc1ccc(I)cc1)c1cccc(C#N)c1.OB(O)c1cc[nH]n1>>CCC(=O)N(Cc1ccc(-c2cc[nH]n2)cc1)c1cccc(C#N)c1 -US20140018533A1,3,CCOC(=O)C1=C(Nc2ccc(OCc3ncccn3)cc2C)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(Nc2ccc(OCc3ncccn3)cc2C)OC(=Cc2c[nH]c3ncccc23)C1=O -US20020028820A1,7,N#Cc1cccc(Oc2ccc([N+](=O)[O-])c(Oc3cccc(C#N)c3)n2)c1>>N#Cc1cccc(Oc2ccc(N)c(Oc3cccc(C#N)c3)n2)c1 -US20140112945A1,2,COc1ccc(C[C@@H](N)C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)[C@H]4CCCC[C@H]4C3=O)CC2)cc1.Cc1[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc2c1C(=O)O>>COc1ccc(C[C@H](NC(=O)c2c(C)[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)[C@H]4CCCC[C@H]4C3=O)CC2)cc1 -US20100093751A1,6,CCOC(=O)Cc1c(C)c(Sc2ccc(S(=O)(=O)N3CCOCC3)cc2F)n2cc(F)ccc12>>Cc1c(CC(=O)O)c2ccc(F)cn2c1Sc1ccc(S(=O)(=O)N2CCOCC2)cc1F -US20060009493A1,1,Cn1cc(CC(=O)NN)ccc1=O.O=C1Nc2ccc(C(=O)O)c(Cl)c2C1=O>>Cn1cc(CC(=O)N/N=C2\C(=O)Nc3ccc(C(=O)O)c(Cl)c32)ccc1=O -US05446164,1,C=O.COc1ccc(CC2NCCc3cc(OC)c(OC)c(O)c32)cc1>>COc1ccc(CC2c3c(cc(OC)c(OC)c3O)CCN2C)cc1 -US20140200227A1,3,CC1(C)OB(c2c(F)cccc2F)OC1(C)C.COC(=O)c1nc(Br)c(F)cc1N>>COC(=O)c1nc(-c2c(F)cccc2F)c(F)cc1N -US20100292279A1,3,C#C[Mg+].O=C(C1CC1)C1CC1>>C#CC(O)(C1CC1)C1CC1 -US04772600,2,CNCCCN1CCN(C)CC1.O=C(O)Cn1c(-c2cccc(Cl)c2)nc2cccnc21>>CN1CCN(CCCN(C)C(=O)Cn2c(-c3cccc(Cl)c3)nc3cccnc32)CC1 -US20120101083A1,1,CC(C)(C)OC(=O)N1CCc2ccc(-c3noc(-c4ccc(F)c(C#N)c4)n3)cc2CC1.CCCN>>CCCNc1ccc(-c2nc(-c3ccc4c(c3)CCN(C(=O)OC(C)(C)C)CC4)no2)cc1C#N -US05834463,6,COc1ccc(CN2C(=O)[C@H]3CCC[C@H]3N(C(=O)CN3C(=O)c4ccccc4C3=O)c3ccccc32)cc1>>O=C1Nc2ccccc2N(C(=O)CN2C(=O)c3ccccc3C2=O)[C@@H]2CCC[C@H]12 -US20120129842A1,4,CC(=O)C(Cl)C(C)=O.CCOC(=O)C(N)=S>>CCOC(=O)c1nc(C)c(C(C)=O)s1 -US04127405,2,COc1nc(N)nc(OC)n1.O=S(=O)(N=C=S)c1ccccc1>>COc1nc(NC(=S)NS(=O)(=O)c2ccccc2)nc(OC)n1 -US05401851,1,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(O)cc1>>COC(=O)[C@@H]1C[C@H](Oc2ccc([N+](=O)[O-])cc2)CN1C(=O)OC(C)(C)C -US20090253687A1,3,Cc1cc(F)ccc1-n1nc(C(F)(F)F)cc1B(O)O.O=C1Cc2ccc(Br)cc2N1>>Cc1cc(F)ccc1-n1nc(C(F)(F)F)cc1-c1ccc2c(c1)NC(=O)C2 -US20150189880A1,1,CC[S-].O=C(Nc1cccc(C(F)(F)F)n1)c1ncccc1Cl>>CCSc1cccnc1C(=O)Nc1cccc(C(F)(F)F)n1 -US20030105092A1,8,CCOC(=O)c1cc(CCCO)[nH]n1>>CCOC(=O)c1cc(CCC=O)[nH]n1 -US06130220,2,CS(=O)(=O)n1cc(C2CCN(S(=O)(=O)Cl)CC2)c2cc(C#N)ccc21.O=C(O)[C@H]1CCCCN1>>CS(=O)(=O)n1cc(C2CCN(S(=O)(=O)N3CCCC[C@@H]3C(=O)O)CC2)c2cc(C#N)ccc21 -US06034275,2,C=CCN(C)CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(N)c1.O=CO>>C=CCN(C)CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(NC=O)c1 -US20140323463A1,1,CCc1nc(C(N)=O)c(Cl)nc1Oc1cccc([N+](=O)[O-])c1.CN1CCN(C2CCN(c3ccc(N)cc3)CC2)CC1>>CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1Oc1cccc([N+](=O)[O-])c1 -US07390835B2,6,CC(C)(O[Si](C)(C)C)C(=O)c1ccc(Cl)cc1>>CC(C)(O)C(=O)c1ccc(Cl)cc1 -US04216333,1,OC(c1ccccc1)(c1ccccc1)c1ccccc1.c1c[nH]cn1>>c1ccc(C(c2ccccc2)(c2ccccc2)n2ccnc2)cc1 -US20080255358A1,1,CCOC(=O)c1cn[nH]c1.Cc1cccc(C)c1CNc1cc(Br)cn2c(C)c(C)nc12>>CCOC(=O)c1cnn(-c2cc(NCc3c(C)cccc3C)c3nc(C)c(C)n3c2)c1 -US05155118,2,Cc1ccc(-c2ccccc2C(=O)O)cc1.N#CCCN>>Cc1ccc(-c2ccccc2C(=O)NCCC#N)cc1 -US20100016295A1,7,COC(=O)C(C)(C)NC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1>>COC(=O)C(C)(C)NC(=O)c1ccc(-c2ccc(N)cc2)cc1 -US20040048897A1,1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2c(Cl)ccc(N)c2O)CC1.O=c1c(Cl)c(Cl)c1=O>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2c(Cl)ccc(Nc3c(Cl)c(=O)c3=O)c2O)CC1 -US06147031,1,BrCc1ccccc1.Cc1c(C(=O)c2cnn(C)c2O)ccc(S(C)(=O)=O)c1C1=NOCC1>>Cc1c(C(=O)c2cnn(C)c2OCc2ccccc2)ccc(S(C)(=O)=O)c1C1=NOCC1 -US08772287B2,1,CC(C)(C)OC(=O)N1CCC(CN)CC1.COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)nc(N2CCOCC2)n1>>COc1cccc2c1nc(C(F)F)n2-c1nc(NCC2CCN(C(=O)OC(C)(C)C)CC2)nc(N2CCOCC2)n1 -US20120053180A1,2,CCc1cnc(OC2CCC(O)CC2)nc1.CS(=O)(=O)Cl>>CCc1cnc(OC2CCC(OS(C)(=O)=O)CC2)nc1 -US20150197509A1,6,CC(C)(C)OC(=O)NCc1cccc(-c2cnc(C(F)(F)F)cn2)c1>>NCc1cccc(-c2cnc(C(F)(F)F)cn2)c1 -US20070010514A1,3,C=C[Mg+].Cc1noc(=O)c2ccc(NC(=O)C(=O)CC(C)(C)c3ccc(F)cc3Cl)cc12>>C=CC(O)(CC(C)(C)c1ccc(F)cc1Cl)C(=O)Nc1ccc2c(=O)onc(C)c2c1 -US20090247577A1,2,CC(C)(C)OC(=O)N1CC(CNC2CC2)C(Cc2cc(F)cc(F)c2)C1.O=C1CC(C(=O)O)c2ccccc2N1>>CC(C)(C)OC(=O)N1CC(Cc2cc(F)cc(F)c2)C(CN(C(=O)C2CC(=O)Nc3ccccc32)C2CC2)C1 -US20110028455A1,3,Cc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2)c1I.OB(O)c1cccs1>>Cc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2)c1-c1cccs1 -US04727180,6,COC(=O)CCc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1SC>>CSc1cc(C(O)(C(F)(F)F)C(F)(F)F)ccc1CCC(=O)O -US06586430B1,1,NC1[C@@H]2CN(Cc3ccccc3)C[C@H]12.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1NC1[C@@H]2CN(Cc3ccccc3)C[C@H]12 -US04518596,1,O=CN1CCNCC1.O=S1CCN(c2nc(Cl)nc3c(SCc4ccc(F)cc4)ncnc23)CC1>>O=CN1CCN(c2nc(N3CCS(=O)CC3)c3ncnc(SCc4ccc(F)cc4)c3n2)CC1 -US20070134737A1,1,CCCCC(CC)CBr.Cc1cc(=O)cc(C)n1-c1ccc(O)cc1>>CCCCC(CC)COc1ccc(-n2c(C)cc(=O)cc2C)cc1 -US20040002524A1,6,COC(=O)c1ccc(-c2nc3ccccc3n2-c2ccc(OC)cc2)s1>>COC(=O)c1ccc(-c2nc3ccccc3n2-c2ccc(O)cc2)s1 -US05630962,2,CCCCCCCC(=O)Cl.CCCCCCCCOc1ccc(-c2ccc(O)c(F)n2)cc1>>CCCCCCCCOc1ccc(-c2ccc(OC(=O)CCCCCCC)c(F)n2)cc1 -US20070112037A1,2,COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(CN)cc2)cc1.CS(=O)(=O)Cl>>COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(CNS(C)(=O)=O)cc2)cc1 -US20080139636A1,7,N#CCc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>NCCc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 -US08389513B2,2,C[C@]1(c2cc(N)ccc2F)N=C(N)OCC1(F)F.Cc1cn[nH]c1C(=O)O>>Cc1cn[nH]c1C(=O)Nc1ccc(F)c([C@@]2(C)N=C(N)OCC2(F)F)c1 -US05552424,7,OCC#Cc1cccc(C2=NOC(c3ccc(F)cc3)C2)c1>>OC/C=C\c1cccc(C2=NOC(c3ccc(F)cc3)C2)c1 -US06727245B2,7,CC(=O)N(C)c1cccc([N+](=O)[O-])c1>>CC(=O)N(C)c1cccc(N)c1 -US08987256B2,6,CCCC(C)C(C(=O)Nc1cccc(CCC(=O)OC(C)(C)C)c1C)c1ccc(CN2N=C(c3ccccc3)OCC2=O)cc1>>CCCC(C)C(C(=O)Nc1cccc(CCC(=O)O)c1C)c1ccc(CN2N=C(c3ccccc3)OCC2=O)cc1 -US08008298B2,6,COC(=O)C1(C)CCOCC1>>CC1(C(=O)O)CCOCC1 -US08673905B2,6,CC(C)(C)OC(=O)NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccsc5)n4)cnc23)CC1>>NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccsc5)n4)cnc23)CC1 -US07902203B2,1,Nn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc21.O=Cc1cccnc1>>O=c1c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc2n1N=Cc1cccnc1 -US06200999B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1onc(O)c1CC(N)C(=O)OCC>>CCOC(=O)c1onc(O)c1CC(NC(=O)OC(C)(C)C)C(=O)OCC -US20110028450A1,3,COc1cc2c(cc1Br)-c1c(Cl)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCC3.OB(O)c1cccnc1>>COc1cc2c(cc1-c1cccnc1)-c1c(Cl)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCC3 -US07202363B2,7,COc1cc(-c2csc3c(/C=C/CO)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C>>COc1cc(-c2csc3c(CCCO)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C -US03985729,3,CBr.O=C1CC(NCCc2ccccc2)c2ccccc21>>CC1(O)CC(NCCc2ccccc2)c2ccccc21 -US20130338358A1,1,CC(C)S(=O)(=O)c1ccccc1Nc1ncnc(Cl)n1.COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1N>>COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncnc(Nc2ccccc2S(=O)(=O)C(C)C)n1 -US07429608B2,1,FC(F)(F)c1ccc2c(c1)nc(Cl)n2CCc1ccccc1.Nc1cccc2ccc(O)cc12>>Oc1ccc2cccc(Nc3nc4cc(C(F)(F)F)ccc4n3CCc3ccccc3)c2c1 -US20090062529A1,6,CC(C)(C)OC(=O)NNC(=O)C(CCCCl)c1cccc(F)c1>>NNC(=O)C(CCCCl)c1cccc(F)c1 -US20030220368A1,8,COc1ncccc1CN1CCC(CO)CC1>>COc1ncccc1CN1CCC(C=O)CC1 -US20020165241A1,1,Clc1nccnc1Cl.NCC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(CNc2nccnc2Cl)CC1 -US20120298932A1,1,O=C(O)c1ccc(-c2ccc(O)cc2)cc1.OCCCCCCBr>>O=C(O)c1ccc(-c2ccc(OCCCCCCO)cc2)cc1 -US20090097096A1,1,C=CCCBr.CCOP(OCC)OCC>>C=CCCP(=O)(OCC)OCC -US08372307B2,2,CCCCCC1CCC(C2CCC(C(=O)O)CC2)CC1.OCCCBr>>CCCCCC1CCC(C2CCC(C(=O)OCCCBr)CC2)CC1 -US04256761,1,CC(C)(C)OC(=O)CBr.NC1CC1>>CC(C)(C)OC(=O)CNC1CC1 -US20150210800A1,6,COC(=O)c1sc2c(c1Br)CSC2>>O=C(O)c1sc2c(c1Br)CSC2 -US05965741,10,COC(=O)c1ccc(C)cc1OC(C)=O.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(CBr)cc1OC(C)=O -US05527805,6,CC(=O)Oc1ccc2ncc3c(c2c1)CCCC3>>Oc1ccc2ncc3c(c2c1)CCCC3 -US05149698,7,OCCCCC#Cc1cncnc1>>OCCCCCCc1cncnc1 -US20030045711A1,2,C=CC[C@H](C)[C@H](O)CC(=O)C(C)(C)C(OC(C)C)OC(C)C.O=C(Cl)OCC(Cl)(Cl)Cl>>C=CC[C@H](C)[C@@H](CC(=O)C(C)(C)C(OC(C)C)OC(C)C)OC(=O)OCC(Cl)(Cl)Cl -US07507841B2,1,Cc1ccc(C(CO)c2ccc(C(C)C)cc2)c(O)c1C>>Cc1ccc2c(c1C)OCC2c1ccc(C(C)C)cc1 -US20140148451A1,1,CCN(CCCCN)S(C)(=O)=O.COc1ccc2nc3cc(Cl)ccc3c(Cl)c2c1>>CCN(CCCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12)S(C)(=O)=O -US05475025,6,CCOC(=O)CCNC(=O)CCNC(=S)Nc1ccc(C=NN)cc1>>NN=Cc1ccc(NC(=S)NCCC(=O)NCCC(=O)O)cc1 -US20070049613A1,6,O=C1c2ccc(-c3ccc(Cl)cc3Cl)cc2[C@H]2CN(Cc3ccccc3)CC[C@@H]12>>O=C1c2ccc(-c3ccc(Cl)cc3Cl)cc2[C@H]2CNCC[C@@H]12 -US20150018343A1,1,CC(C)(C)[Si](C)(C)OCC=O.CNCCOc1ccccc1C(=O)N1Cc2nn3c(C)c(Cl)c(C)nc3c2C1>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OCCN(C)CCO[Si](C)(C)C(C)(C)C)C3 -US20150148337A1,3,Cc1noc2c1-c1ccc(Cl)cc1C(=O)N(C(=O)OC(C)(C)C)[C@H]2CC(=O)OC(C)(C)C.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cc1noc2c1-c1ccc(-c3cnn(C)c3)cc1C(=O)N(C(=O)OC(C)(C)C)[C@H]2CC(=O)OC(C)(C)C -US20110009609A1,2,COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](O)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1.O=C=Nc1ccccc1>>COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](O)[C@@H]2OC(=O)Nc2ccccc2)(c2ccccc2)c2ccc(OC)cc2)cc1 -US07208494B2,1,C[C@H](CNC(=O)OC(C)(C)C)n1c(CO)cc2cc(F)cnc21>>C[C@@H]1CN(C(=O)OC(C)(C)C)Cc2cc3cc(F)cnc3n21 -US20060264415A1,6,COC(=O)c1ccc(COCC(=O)NCCCCCC(=O)Nc2cccc(-c3ccccc3)c2)cc1>>O=C(COCc1ccc(C(=O)O)cc1)NCCCCCC(=O)Nc1cccc(-c2ccccc2)c1 -US20070254866A1,2,CCO.COc1c(NCCNc2ccccn2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12>>CCOC(=O)c1cn(C2CC2)c2c(OC)c(NCCNc3ccccn3)c(F)c(N)c2c1=O -US20150087639A1,1,C1COCCN1.O=[N+]([O-])c1ccc(CBr)c(F)c1>>O=[N+]([O-])c1ccc(CN2CCOCC2)c(F)c1 -US05516904,1,CC(C)CCBr.Sc1ccc(Br)cc1>>CC(C)CCSc1ccc(Br)cc1 -US20050136444A1,1,COc1ccc(C=O)c(C)c1C.N=C(N)NN>>COc1ccc(C=NNC(=N)N)c(C)c1C -US06444694B1,6,COC(=O)c1ccc2[nH]c(C=Cc3ccc(OC)c(OC)c3)nc2c1>>COc1ccc(/C=C/c2nc3cc(C(=O)O)ccc3[nH]2)cc1OC -US20150239900A1,6,COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1>>COC(=O)[C@@H]1CNCCN1 -US20120010182A1,1,C=O.O=S(=O)(Nc1nncs1)c1cc(Cl)c(Oc2ccc(-c3ccc(C(F)(F)F)cc3)cc2-c2ccnn2C2CNC2)cc1F>>CN1CC(n2nccc2-c2cc(-c3ccc(C(F)(F)F)cc3)ccc2Oc2cc(F)c(S(=O)(=O)Nc3nncs3)cc2Cl)C1 -US07115611B2,6,COC(=O)COc1ccc(N(C)Cc2cnc(-c3ccc(C(F)(F)F)cc3)nc2C2CC2)cc1C>>Cc1cc(N(C)Cc2cnc(-c3ccc(C(F)(F)F)cc3)nc2C2CC2)ccc1OCC(=O)O -US20080167309A1,6,CCOC(=O)c1ncsc1NC(C)c1ccccc1>>CC(Nc1scnc1C(=O)O)c1ccccc1 -US08569522B2,7,NCC/C=C\c1cccc(Cl)c1>>NCCCCc1cccc(Cl)c1 -US20150045553A1,9,CC(C)(C)N1CCC(Oc2ccc(-n3cc(C(N)=O)nn3)cc2)CC1>>CC(C)(C)N1CCC(Oc2ccc(-n3cc(C#N)nn3)cc2)CC1 -US06018046,6,COc1cc2c(=O)c(Cc3ccccn3)cn3c4ccc(Br)cc4c(c1)c23>>O=c1c(Cc2ccccn2)cn2c3ccc(Br)cc3c3cc(O)cc1c32 -US04853463,2,CC(C)C[C@H](N)C(O)C(=O)OC(C)C.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(O)C(=O)OC(C)C -US20070049564A1,1,CC(C)(C)CC(=O)O.CCSC(=O)OCCl>>CCSC(=O)OCOC(=O)CC(C)(C)C -US20040180874A1,1,Brc1cccc2cnccc12.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2cccc3cnccc23)CC1 -US04518597,6,COc1ccc2c(c1)C(C)(C)OC(=O)N2>>CC1(C)OC(=O)Nc2ccc(O)cc21 -US05256675,1,O=CNc1nc(CCl)cs1.Sc1ccncc1>>O=CNc1nc(CSc2ccncc2)cs1 -US20120208798A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccc(Br)cc1>>CC(C)(C)OC(=O)NCCc1ccc(Br)cc1 -US06727264B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.O=C(CCCCCl)c1ccccc1Cl>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccccc3Cl)CC2)c1 -US08754114B2,2,O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CCNCC5)c4)cnn23)c1.O=C=NCc1ccccc1>>O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CCN(C(=O)NCc6ccccc6)CC5)c4)cnn23)c1 -US06300334B1,1,CC(C)Cn1c(=O)n(C)c(=O)c2c(Br)c(C(=O)c3nc4ccccc4n3C)sc21.CC(C)S>>CC(C)Cn1c(=O)n(C)c(=O)c2c(SC(C)C)c(C(=O)c3nc4ccccc4n3C)sc21 -US03998971,1,C=COCCN.CC(=O)Cc1cccc(C(F)(F)F)c1>>C=COCCNC(C)Cc1cccc(C(F)(F)F)c1 -US20050026968A1,2,Nc1ccc(N2CCC(Cc3ccccc3)CC2)cc1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>O=C(Nc1ccc(N2CCC(Cc3ccccc3)CC2)cc1)c1ccc([N+](=O)[O-])o1 -US04024273,9,CCc1ccc(C=C(Br)Br)cc1>>C#Cc1ccc(CC)cc1 -US07622471B2,6,COc1ccc(-n2nc(C(=O)N3CCN(Cc4ccccc4)C(C)C3)cc2-c2ccccc2)cn1>>COc1ccc(-n2nc(C(=O)N3CCNC(C)C3)cc2-c2ccccc2)cn1 -US20090105229A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Fc1ccc2c(c1)NCC2>>CC(C)(C)OC(=O)N1CCc2ccc(F)cc21 -US20100004222A1,6,O=[N+]([O-])c1cnc2c(c1)CC1(CC2)OCCO1>>O=C1CCc2ncc([N+](=O)[O-])cc2C1 -US20080132477A1,1,C=CCN.COCc1cc(C(=O)OC(C)(C)C)cc(Cl)n1>>C=CCNc1cc(C(=O)OC(C)(C)C)cc(COC)n1 -US05457106,3,O=C1CSC(=S)N1.O=Cc1ccccc1>>O=C1NC(=S)SC1=Cc1ccccc1 -US20120202832A1,2,C#Cc1cc(Nc2ncnc3cnc(N)cc23)ccc1F.CCOP(=O)(CC(=O)O)OCC>>C#Cc1cc(Nc2ncnc3cnc(NC(=O)CP(=O)(OCC)OCC)cc23)ccc1F -US08759535B2,1,CN.NC(=O)Cc1ccc([N+](=O)[O-])c(Cl)c1>>CNc1cc(CC(N)=O)ccc1[N+](=O)[O-] -US20110021556A1,2,CC(=O)OC(C)=O.Nc1ccc(C2(Cc3ccccc3)CCN(Cc3ccccc3)C2)cc1>>CC(=O)Nc1ccc(C2(Cc3ccccc3)CCN(Cc3ccccc3)C2)cc1 -US07265113B2,1,Cc1c(OCCCNS(C)(=O)=O)cn2ncnc(O)c12.Cc1cc2c(F)c(O)ccc2[nH]1>>Cc1cc2c(F)c(Oc3ncnn4cc(OCCCNS(C)(=O)=O)c(C)c34)ccc2[nH]1 -US07560558B2,1,CC(C)CCOC(=O)c1ccccc1O.COc1cc2nccc(Cl)c2cc1OC>>COc1cc2nccc(Oc3ccccc3C(=O)OCCC(C)C)c2cc1OC -US20150182513A1,6,COc1cnn(-c2ccc(-c3ccn(CC[C@](C)(C(=O)NOC4CCCCO4)S(C)(=O)=O)c(=O)c3)cc2)n1>>COc1cnn(-c2ccc(-c3ccn(CC[C@](C)(C(=O)NO)S(C)(=O)=O)c(=O)c3)cc2)n1 -US20060074238A1,8,CCN(CC)C(=O)c1ccc(C(O)c2cccc3cccnc23)cc1>>CCN(CC)C(=O)c1ccc(C(=O)c2cccc3cccnc23)cc1 -US20110178053A1,1,C[S-].Nc1ncccc1-c1cc(Cl)ncc1Cl>>CSc1cc(-c2cccnc2N)c(Cl)cn1 -US20150157639A1,1,NC1CCC2(CC1)OCCO2.NS(=O)(=O)c1ccc(F)c([N+](=O)[O-])c1>>NS(=O)(=O)c1ccc(NC2CCC3(CC2)OCCO3)c([N+](=O)[O-])c1 -US08231858B2,6,COC(=O)c1ccc(CN(C(C(=O)OC(C)(C)C)C(C)C)S(=O)(=O)c2ccc(OC)cc2)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccc(C(=O)O)cc2)C(C(=O)OC(C)(C)C)C(C)C)cc1 -US05945450,2,Nc1ccccc1.O=C(O)c1ccc(Oc2ccc3ccccc3c2)cc1>>O=C(Nc1ccccc1)c1ccc(Oc2ccc3ccccc3c2)cc1 -US20140349993A1,6,CC(C)(C)OC(=O)Nc1cccc(CN2CCC(F)(F)CC2)n1>>Nc1cccc(CN2CCC(F)(F)CC2)n1 -US20010034448A1,7,Cc1cc2c(cc1C1=CCCC1=O)C(C)(C)CCC2(C)C>>Cc1cc2c(cc1C1=CCCC1O)C(C)(C)CCC2(C)C -US20140142085A1,7,NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CC(=O)CC3)ccc1F>>NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CC(O)CC3)ccc1F -US20150197509A1,2,CC(C)N(CC(=O)O)S(=O)(=O)c1ccc(F)cc1.NCc1cc(-c2ccc(C(F)(F)F)cc2)ccc1F>>CC(C)N(CC(=O)NCc1cc(-c2ccc(C(F)(F)F)cc2)ccc1F)S(=O)(=O)c1ccc(F)cc1 -US06174898B1,6,CCOC(=O)[C@@H]1CCCN(CCOCC=C(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)C1>>O=C(O)[C@@H]1CCCN(CCOCC=C(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)C1 -US20150210720A1,2,CC(=O)O.CCOc1nc(N2CCN(C(C)=O)CC2)ccc1NC(=O)c1coc2c1C(=O)NC1(CNC1)C2>>CCOc1nc(N2CCN(C(C)=O)CC2)ccc1NC(=O)c1coc2c1C(=O)NC1(C2)CN(C(C)=O)C1 -US06107308,7,C(=C1CCNCC1)c1ccc2ccccc2n1>>c1ccc2nc(CC3CCNCC3)ccc2c1 -US20140378446A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCCOc1cc(N)cc([N+](=O)[O-])c1>>COCCOc1cc(NC(=O)OC(C)(C)C)cc([N+](=O)[O-])c1 -US20120101134A1,6,CCOC(=O)CCCc1cc(F)cc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c1OC>>COc1c(CCCC(=O)O)cc(F)cc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 -US07977345B2,6,O=C(Nc1ccc(F)cc1)C1(C(=O)Nc2ccc(Oc3ncnc4c3cnn4C3CCCCO3)cc2)CC1>>O=C(Nc1ccc(F)cc1)C1(C(=O)Nc2ccc(Oc3ncnc4[nH]ncc34)cc2)CC1 -US20090170914A1,7,Nc1nc2ccc([N+](=O)[O-])cc2s1>>Nc1ccc2nc(N)sc2c1 -US20060089367A1,2,CCCCCCCN.O=C(O)c1ccc2c(c1)nc(COc1ccccc1)n2Cc1ccc(OC(F)(F)F)cc1>>CCCCCCCNC(=O)c1ccc2c(c1)nc(COc1ccccc1)n2Cc1ccc(OC(F)(F)F)cc1 -US20130035310A1,2,CC(C)C[C@H](C(=O)O)N1CCCc2cc(Cl)ccc21.O=C1CNCCN1c1ccc(S(=O)(=O)Nc2nccs2)cc1>>CC(C)C[C@H](C(=O)N1CCN(c2ccc(S(=O)(=O)Nc3nccs3)cc2)C(=O)C1)N1CCCc2cc(Cl)ccc21 -US20140323475A1,3,C[Mg+].O=Cc1cc(Cl)ccc1OCc1ccc(Cl)cc1F>>CC(O)c1cc(Cl)ccc1OCc1ccc(Cl)cc1F -US05665718,6,CCOC(=O)c1ncn2c1[C@@H]1CCN1C(=O)c1sccc1-2>>O=C(O)c1ncn2c1[C@@H]1CCN1C(=O)c1sccc1-2 -US20110275630A1,2,COC(=O)c1cc(N)cc([N+](=O)[O-])c1C.O=C(Cl)OCc1ccccc1>>COC(=O)c1cc(NC(=O)OCc2ccccc2)cc([N+](=O)[O-])c1C -US20150018341A1,1,CCC(=C(c1ccc(O)cc1)c1ccc(OCCCl)cc1)c1ccc2oc(Cl)cc2c1.CN>>CCC(=C(c1ccc(O)cc1)c1ccc(OCCNC)cc1)c1ccc2oc(Cl)cc2c1 -US20120010182A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCN(c2cc(-c3cc(Cl)ccc3O)ccn2)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(-c3cc(Cl)ccc3OCc3ccccc3)ccn2)CC1 -US07635715B2,2,CC(C)(C)OC(=O)CN.CCOC(=O)C1=C(O)c2ccccc2C2(CCOCC2)C1=O>>CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccccc2C2(CCOCC2)C1=O -US20040122084A1,2,CC1CCN(C2C3=CC(OC3=O)C3C(CC4(C)OC4C2O)OC(=O)C3C)CC1.CCOC(=O)Cl>>CCOC(=O)OC1C(N2CCC(C)CC2)C2=CC(OC2=O)C2C(CC3(C)OC13)OC(=O)C2C -US07893058B2,2,Nc1ccc([N+](=O)[O-])cn1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1ccc([N+](=O)[O-])cn1 -US20080070935A1,1,Cc1c[nH]c2c1C(=O)CC(C)(C)C2.Nc1ncnc2cc(F)cnc12>>Cc1cn(-c2cnc3c(N)ncnc3c2)c2c1C(=O)CC(C)(C)C2 -US20090275570A1,1,CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3sc(Br)cc23)C1.CI>>CN(c1ncc(C#N)c2sc(Br)cc12)[C@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20050054710A1,2,CN(C)CCN.Nc1ccc(S(=O)(=O)O)cc1>>CN(C)CCNS(=O)(=O)c1ccc(N)cc1 -US20140128385A1,2,NC[C@@](O)(c1cccc(F)c1F)C(F)F.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NC[C@@](O)(c1cccc(F)c1F)C(F)F -US20120172347A1,2,Cn1c(=O)[nH]c2cnc(/C=C/c3ccccc3)nc21.O=C(Cl)N1CCCC1>>Cn1c(=O)n(C(=O)N2CCCC2)c2cnc(/C=C/c3ccccc3)nc21 -US07820655B2,3,COc1ccc2ncc(F)c(Br)c2n1.OB(O)/C=C/c1ccccc1>>COc1ccc2ncc(F)c(/C=C/c3ccccc3)c2n1 -US20150148332A1,1,COCCBr.Cc1c(Cl)cc(O)c2nc(CCc3nc(N4CCCC4)nn3C)nn12>>COCCOc1cc(Cl)c(C)n2nc(CCc3nc(N4CCCC4)nn3C)nc12 -US04372952,6,CCOC(=O)C(=NOCc1ccc(Cl)cc1)c1csc(N)n1>>Nc1nc(C(=NOCc2ccc(Cl)cc2)C(=O)O)cs1 -US20090209561A1,3,C=CCn1cnc2c1c(=O)n(C)c(=O)n2CCCCC.CN(C)C=O>>C=CCn1c(C=O)nc2c1c(=O)n(C)c(=O)n2CCCCC -US05624926,1,COc1cc2ncnc(N3CCC(n4c(=O)[nH]c5ccc([N+](=O)[O-])cc5c4=O)CC3)c2cc1OC.N#CCBr>>COc1cc2ncnc(N3CCC(n4c(=O)c5cc([N+](=O)[O-])ccc5n(CC#N)c4=O)CC3)c2cc1OC -US05055622,7,C/C(=C\c1ccccc1)c1ccc2c(c1)C(C)(C)C(=O)C2(C)C>>C/C(=C\c1ccccc1)c1ccc2c(c1)C(C)(C)C(O)C2(C)C -US20140275071A1,1,CCCN.Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2c1nc(Br)n2Cc1ccc(Cl)cc1>>CCCNc1nc2c(c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)n2C)n1Cc1ccc(Cl)cc1 -US20140073628A1,6,COc1ccc(-c2ccc3c(c2)CN(C(=O)OC(C)(C)C)CCO3)cc1OC(F)F>>COc1ccc(-c2ccc3c(c2)CNCCO3)cc1OC(F)F -US08629166B2,2,Nc1ccccn1.O=C(O)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1>>O=C(Nc1ccccn1)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1 -US08163755B2,6,COC(=O)C1(C)COCCN1Cc1ccccc1>>COC(=O)C1(C)COCCN1 -US08063061B2,2,CCOCC(=O)O.Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(C(=O)CN)ccc3[nH]c21>>CCOCC(=O)NCC(=O)c1ccc2[nH]c3c(cc(-c4ccc(Cl)cc4Cl)c(=O)n3C)c2c1 -US20090298856A1,6,CCOC(=O)CC1CCC(F)(F)CC1>>O=C(O)CC1CCC(F)(F)CC1 -US20090318693A1,1,NNC(=O)c1ccc(O)cc1.O=Cc1ccccc1>>O=C(NN=Cc1ccccc1)c1ccc(O)cc1 -US05124324,1,BrCc1ccccc1.C[SiH](C)OC(C1CCCCN1)C(C)(C)C>>C[SiH](C)OC(C1CCCCN1Cc1ccccc1)C(C)(C)C -US20090306133A1,3,CC(=O)c1ccc(B(O)O)s1.O=C(O)c1cc(Cl)nc2ccccc12>>CC(=O)c1ccc(-c2cc(C(=O)O)c3ccccc3n2)s1 -US05134128,7,OCCCC#Cc1ccc2ccccc2c1>>OCCCCCc1ccc2ccccc2c1 -US20060019984A1,6,CCOC(=O)c1ccc2c(c1)C=CCO2>>O=C(O)c1ccc2c(c1)C=CCO2 -US20040077618A1,6,CCOC(=O)C1CC1(C1CC1)C1CC1>>O=C(O)C1CC1(C1CC1)C1CC1 -US20030199550A1,8,CN(C[C@@H]1CC[C@@H](CO)CC1)C(=O)OCc1ccccc1>>CN(C[C@@H]1CC[C@@H](C=O)CC1)C(=O)OCc1ccccc1 -US20140105921A1,2,COC[C@H](NC(=O)c1cnc(C)s1)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@](C)(O)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>COC[C@H](NC(=O)c1cnc(C)s1)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@](C)(O)COS(=O)(=O)c1ccc(C)cc1 -US20120129840A1,3,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1Cl.[Mg+]Cc1ccccc1>>CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1Cc1ccccc1 -US20080249091A1,1,CC(C)(C)C(N)=O.CCOC(=O)c1c(I)c2cc(OCc3ccccc3)ccc2n1-c1ccc(OC(C)C)cc1>>CCOC(=O)c1c(NC(=O)C(C)(C)C)c2cc(OCc3ccccc3)ccc2n1-c1ccc(OC(C)C)cc1 -US08680108B2,7,COC(=O)c1cc(Cl)c(C#C[Si](C)(C)C)c([N+](=O)[O-])c1-c1cccc(F)c1>>COC(=O)c1cc(Cl)c(C#C[Si](C)(C)C)c(N)c1-c1cccc(F)c1 -US08288544B2,6,CC(C)(C)OC(=O)NCCc1cn(C(=O)OC(C)(C)C)cn1>>CC(C)(C)OC(=O)NCCc1c[nH]cn1 -US05708018,6,CCCN(CCC)C1Cc2cc(OC)c(C(=O)OC)cc2C1>>CCCN(CCC)C1Cc2cc(OC)c(C(=O)O)cc2C1 -US08952004B2,3,CN1CCCN(C(=O)CC2CCN(c3ncc(Br)cc3NC(=O)c3cccc(Cl)c3)CC2)CC1.OB(O)c1cccnc1>>CN1CCCN(C(=O)CC2CCN(c3ncc(-c4cccnc4)cc3NC(=O)c3cccc(Cl)c3)CC2)CC1 -US20080275233A1,1,O=C(NCCCl)Nc1ccc(C(F)(F)F)cc1>>O=C1NCCN1c1ccc(C(F)(F)F)cc1 -US05530124,8,O=C(O)N(Cc1ccccc1)[C@@H](CO)Cc1ccccc1>>O=C[C@@H](Cc1ccccc1)N(Cc1ccccc1)C(=O)O -US08609688B2,6,CC(C)(C)OC(=O)NC1(c2ccc(-n3c(-c4cccnc4N)nc4ccc(-c5cccc(N6CCO[C@H](COCc7ccccc7)C6)c5)nc43)cc2)CCC1>>CC(C)(C)OC(=O)NC1(c2ccc(-n3c(-c4cccnc4N)nc4ccc(-c5cccc(N6CCO[C@H](CO)C6)c5)nc43)cc2)CCC1 -US20140378487A1,1,O=Cc1ccc(F)c(Br)c1.Oc1cccc(C(F)(F)F)c1>>O=Cc1ccc(Oc2cccc(C(F)(F)F)c2)c(Br)c1 -US20110166182A1,6,COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3cccs3)ccc2c1>>Oc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3cccs3)ccc2c1 -US08361994B2,1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.O=C(O)c1ccccc1>>CC(C)(C)OC(=O)N1CC[C@H](OC(=O)c2ccccc2)C1 -US20130331378A1,6,COC(=O)c1cccc(Cc2c(-c3ccccc3)nn3cc(F)ccc23)n1>>O=C(O)c1cccc(Cc2c(-c3ccccc3)nn3cc(F)ccc23)n1 -US06730793B1,1,CCCCCCCCCCC1(CCCCCCCCCC)c2cc(Br)ccc2-c2ccc(I)cc21.c1ccc(Nc2ccccc2)cc1>>CCCCCCCCCCC1(CCCCCCCCCC)c2cc(Br)ccc2-c2ccc(N(c3ccccc3)c3ccccc3)cc21 -US09145391B2,3,COC(=O)[C@@H]1CC[C@@H](C(=O)Cl)CC1.C[Si](C)(C)c1ccc(Br)cn1>>COC(=O)[C@@H]1CC[C@@H](C(=O)c2ccc(Br)cn2)CC1 -US05476875,8,COc1cc(C(O)c2ccc(C(F)(F)F)cc2)ccc1OCc1ccccc1>>COc1cc(C(=O)c2ccc(C(F)(F)F)cc2)ccc1OCc1ccccc1 -US20070129552A1,3,C=CC(=O)OC.OCc1cccc(I)c1>>COC(=O)/C=C/c1cccc(CO)c1 -US07402585B2,1,CC(C)(C)OCCBr.COc1cc(C#N)c(N=CN(C)C)cc1OC[C@H]1CCCN1>>COc1cc(C#N)c(N=CN(C)C)cc1OC[C@H]1CCCN1CCOC(C)(C)C -US08674115B2,6,CCOC(=O)Cn1c(C)c(Cc2ccccc2S(=O)(=O)N2CCCC2)c(C#N)c1C1CCCCC1>>Cc1c(Cc2ccccc2S(=O)(=O)N2CCCC2)c(C#N)c(C2CCCCC2)n1CC(=O)O -US20030225122A1,1,COC(=O)Cc1cccc(O)c1.Fc1ccc(CBr)cc1>>COC(=O)Cc1cccc(OCc2ccc(F)cc2)c1 -US20100311684A1,9,C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cc(I)c2c(Cl)ncnc21.N>>C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cc(I)c2c(N)ncnc21 -US20060009464A1,1,CC(CC=O)(C(=O)C1CCCCC1)c1ccccc1.COc1ccccc1N1CCNCC1>>COc1ccccc1N1CCN(CCC(C)(C(=O)C2CCCCC2)c2ccccc2)CC1 -US05273986,7,CCOC(=O)c1csc(C2CCC2)n1>>OCc1csc(C2CCC2)n1 -US20090215759A1,1,COc1cc(Nc2cc(C(F)(F)F)cc(Cl)n2)ccc1-n1cnc(C)c1.Nc1cccc(C(F)(F)F)c1>>COc1cc(Nc2cc(C(F)(F)F)cc(Nc3cccc(C(F)(F)F)c3)n2)ccc1-n1cnc(C)c1 -US20050043300A1,1,COC(=O)[C@@H](C)O.COC(=O)c1ccc(O)c(OC)c1>>COC(=O)c1ccc(O[C@@H](C)C(=O)OC)c(OC)c1 -US20060128684A1,6,Cc1nccn1-c1cc(NC(=O)OC(C)(C)C)cc(C(F)(F)F)c1>>Cc1nccn1-c1cc(N)cc(C(F)(F)F)c1 -US20060074119A1,1,COC(=O)c1sc(-n2cnc3cc(OC)c(O)cc32)cc1OCc1ccccc1C(F)(F)F.OCCCl>>COC(=O)c1sc(-n2cnc3cc(OC)c(OCCCl)cc32)cc1OCc1ccccc1C(F)(F)F -US20050222424A1,6,CCOC(=O)C(C)(C)Oc1ccc(CN(Cc2cccs2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C>>Cc1cc(CN(Cc2cccs2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OC(C)(C)C(=O)O -US08404859B2,2,COC(=O)[C@H](CN)NC(=O)c1sc(C(=O)NCc2cccc3[nH]ccc23)cc1C(F)(F)F.O=C(O)c1cccs1>>COC(=O)[C@H](CNC(=O)c1cccs1)NC(=O)c1sc(C(=O)NCc2cccc3[nH]ccc23)cc1C(F)(F)F -US07790709B2,2,CNCc1ccc(F)c2ccccc12.O=C(O)/C=C/c1cnc2c(c1)CN(CCN1CCOCC1)C(=O)N2>>CN(Cc1ccc(F)c2ccccc12)C(=O)/C=C/c1cnc2c(c1)CN(CCN1CCOCC1)C(=O)N2 -US04713396,2,Nc1cc(Cl)cc(C(F)(F)F)c1Cl.O=C=NC(=O)c1c(F)cccc1F>>O=C(NC(=O)c1c(F)cccc1F)Nc1cc(Cl)cc(C(F)(F)F)c1Cl -US07435744B2,2,Nc1ccc(S(N)(=O)=O)cc1.O=C(O)C(=O)N1CCC(Cc2ccccc2)CC1>>NS(=O)(=O)c1ccc(NC(=O)C(=O)N2CCC(Cc3ccccc3)CC2)cc1 -US20030225125A1,7,O=C(O)c1c(Cl)ccc([N+](=O)[O-])c1Cl>>Nc1ccc(Cl)c(C(=O)O)c1Cl -US06063782,1,COC(=O)c1[nH]c(C)c(C)c1C=O.ClCC=C(Cl)Cl>>COC(=O)c1c(C=O)c(C)c(C)n1CC=C(Cl)Cl -US20130137709A1,2,C=CC(=O)Cl.CNC(=O)c1ccccc1Nc1nc(Nc2cc(N)ccc2OC)nc2c1c(Cl)cn2COCC[Si](C)(C)C>>C=CC(=O)Nc1ccc(OC)c(Nc2nc(Nc3ccccc3C(=O)NC)c3c(Cl)cn(COCC[Si](C)(C)C)c3n2)c1 -US20130345180A1,1,Clc1ccnc(Cl)n1.Nc1ccccc1S(N)(=O)=O>>NS(=O)(=O)c1ccccc1Nc1ccnc(Cl)n1 -US20140066457A1,2,COc1ccc2c(CCN)c[nH]c2c1.O=C(O)c1cc(Cc2cccc(F)c2)on1>>COc1ccc2c(CCNC(=O)c3cc(Cc4cccc(F)c4)on3)c[nH]c2c1 -US20140275030A1,3,C[Zn+].Cc1noc(C)c1-c1ccc2nc(Cl)n3c2c1OCC3c1ccccn1>>Cc1noc(C)c1-c1ccc2nc(C)n3c2c1OCC3c1ccccn1 -US06008230,7,COc1c(C(C)=O)cnc2c([N+](=O)[O-])cccc12>>COc1c(C(C)=O)cnc2c(N)cccc12 -US09050344B2,3,CC1(C)OB(c2cccc(C(N)=O)c2)OC1(C)C.Nc1ccc(Br)c(C(Cc2cc(F)cc(F)c2)NC(=O)Cc2c[nH]c3ccc(F)cc23)n1>>NC(=O)c1cccc(-c2ccc(N)nc2C(Cc2cc(F)cc(F)c2)NC(=O)Cc2c[nH]c3ccc(F)cc23)c1 -US07217724B2,6,C[C@H](Cc1c[nH]c2c(NC(=O)OC(C)(C)C)cccc12)N1C[C@@H](c2cccc(Cl)c2)OC1=O>>C[C@H](Cc1c[nH]c2c(N)cccc12)N1C[C@@H](c2cccc(Cl)c2)OC1=O -US04197296,9,C/C=C1/CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C.NO>>C/C=C1/CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=NO)C[C@]12C -US20090062349A1,4,COC(=O)C1=CCCC1.O=C(OO)c1cccc(Cl)c1>>COC(=O)C12CCCC1O2 -US07314937B2,2,CC(C)N=C=O.c1cc2c(cc1OCCCN1CCCCC1)CNCC2>>CC(C)NC(=O)N1CCc2ccc(OCCCN3CCCCC3)cc2C1 -US20150239902A1,1,Clc1ncnc2c1OCCN2.FC(F)(F)c1cc(-c2cn(CCN3CCC3)c(C3CCNCC3)n2)ccn1>>FC(F)(F)c1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc5c4OCCN5)CC3)n2)ccn1 -US05648354,6,CN(C)c1cccc(OCC2=CC=C(CO[Si](C)(C)C(C)(C)C)SS2)c1>>CN(C)c1cccc(OCC2=CC=C(CO)SS2)c1 -US06458781B1,2,CC(C)C[C@H](N)CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1.O=C(Cl)N1CCCCCC1>>CC(C)C[C@@H](CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)NC(=O)N1CCCCCC1 -US20040048897A1,1,CCN(CC)CCN(C)S(=O)(=O)c1c(Cl)ccc(N)c1O.O=c1c(Cl)c(Cl)c1=O>>CCN(CC)CCN(C)S(=O)(=O)c1c(Cl)ccc(Nc2c(Cl)c(=O)c2=O)c1O -US20080269210A1,2,Nc1ncc(-c2nc(N3CCOCC3)c3sc(C(=O)O)cc3n2)cn1.OCCN1CCNCC1>>Nc1ncc(-c2nc(N3CCOCC3)c3sc(C(=O)N4CCN(CCO)CC4)cc3n2)cn1 -US20150087639A1,7,CC(C)(Cc1ccc(Cl)c(F)c1)Nc1ccc([N+](=O)[O-])cc1Cl>>CC(C)(Cc1ccc(Cl)c(F)c1)Nc1ccc(N)cc1Cl -US20150126513A1,1,COc1ccc(C(=O)C2CCN(C3CCNC3=O)CC2)cc1.O=c1[nH]c(CCl)nc2c1COCC2>>COc1ccc(C(=O)C2CCN(C3CCN(Cc4nc5c(c(=O)[nH]4)COCC5)C3=O)CC2)cc1 -US07998949B2,1,CN1CCN([C@H]2CC[C@@H](OS(C)(=O)=O)CC2)CC1=O.COc1cc2ncn(Cc3ccccc3)c(=O)c2cc1O>>COc1cc2ncn(Cc3ccccc3)c(=O)c2cc1O[C@@H]1CC[C@@H](N2CCN(C)C(=O)C2)CC1 -US06566337B1,2,CN(C(=O)OC(C)(C)C)[C@H](Cc1ccccc1)C(=O)O.CNCCc1ccccn1>>CN(CCc1ccccn1)C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)OC(C)(C)C -US20140081017A1,3,COC(=O)Cc1ccc(CCCC(=O)c2ccccc2)cc1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(CCCc1ccc(CC(=O)OC)cc1)c1ccccc1 -US20140142083A1,1,COC(=O)c1cc(Cl)cc(N)c1C.O=C1CCC2(CC1)OCCO2>>COC(=O)c1cc(Cl)cc(NC2CCC3(CC2)OCCO3)c1C -US20140271662A1,3,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CNCCC(c1ccc(Cl)cc1)c1ccc(Br)cc1>>CNCCC(c1ccc(Cl)cc1)c1ccc(-c2cn[nH]c2)cc1 -US20150080393A1,6,CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(Br)cc4-n4ccc(C)n4)C(F)(F)F)nc(C)n3)CC2)CN1>>Cc1ccn(-c2cc(Br)ccc2[C@@H](Oc2cc(N3CCC4(CC3)CN[C@H](C(=O)O)C4)nc(C)n2)C(F)(F)F)n1 -US05298652,1,BrCc1ccccc1.CCCCCCCCCCCCCCOc1ccc(O)c(C(=O)OC)c1>>CCCCCCCCCCCCCCOc1ccc(OCc2ccccc2)c(C(=O)OC)c1 -US20120289522A1,1,BrCc1ccccc1.Cc1noc(-c2ccc(Br)cc2)c1CC(=O)O>>Cc1noc(-c2ccc(Br)cc2)c1CC(=O)OCc1ccccc1 -US20150182513A1,3,COc1cnn(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)n1.C[C@@](CCn1ccc(I)cc1=O)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>COc1cnn(-c2ccc(-c3ccn(CC[C@](C)(C(=O)NOC4CCCCO4)S(C)(=O)=O)c(=O)c3)cc2)n1 -US07115611B2,6,CCOC(=O)C(C)(C)Oc1ccc(OCc2ccc(-c3ccc(C(F)(F)F)cc3)nn2)cc1C>>Cc1cc(OCc2ccc(-c3ccc(C(F)(F)F)cc3)nn2)ccc1OC(C)(C)C(=O)O -US20070259965A1,9,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCCN(C)S(=O)(=O)c1sccc1Br.[C-]#N>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCCN(C)S(=O)(=O)c1sccc1C#N -US08269008B2,2,CCOC(=O)c1nc(C#N)c2c(-c3ccc(OC)cc3)noc2c1O.NCC(=O)O>>COc1ccc(-c2noc3c(O)c(C(=O)NCC(=O)O)nc(C#N)c23)cc1 -US04394515,7,O=C(O)c1ccc2c(c1)Sc1ccccc1CC2=O>>O=C(O)c1ccc2c(c1)Sc1ccccc1CC2O -US20140243336A1,2,CCOCC(CO)NC(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CCOCC(COS(C)(=O)=O)NC(=O)OC(C)(C)C -US20050148627A1,7,Cc1cc(Br)c(N)c(C(=O)O)c1>>Cc1cc(Br)c(N)c(CO)c1 -US20150225397A1,7,CC1=C2CCC[C@H](O)[C@@]2(c2ccccc2)CCC1=O>>C[C@@H]1C(=O)CC[C@@]2(c3ccccc3)[C@H]1CCC[C@@H]2O -US07705004B2,1,Cc1ccc(S(=O)(=O)n2cc(C)c3c(Cl)nc(Cl)nc32)cc1.Nc1ccc2cn[nH]c2c1>>Cc1ccc(S(=O)(=O)n2cc(C)c3c(Nc4ccc5cn[nH]c5c4)nc(Cl)nc32)cc1 -US20150031674A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)CCl>>CC(C)(C)OC(=O)N1CCN(C(=O)CCl)CC1 -US20110263571A1,2,CCOC(=O)c1ccc(N2C(=O)OC[C@H]2c2ccccc2)cc1.Cc1cnc(N2CCNCC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4c4ccccc4)cc3)CC2)c(C)c1 -US20070293567A1,1,COC(=O)C(CC(C)C)c1cc(O)cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1.OB(O)c1cccc(C(F)(F)F)c1>>COC(=O)C(CC(C)C)c1cc(Oc2cccc(C(F)(F)F)c2)cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 -US20140107078A1,1,CCOC(=O)CBr.O=Cc1cc(Cl)c(O)c(Cl)c1>>CCOC(=O)COc1c(Cl)cc(C=O)cc1Cl -US20070299077A1,7,CC(C)(C)OC(=O)N1CC2CC1CN2c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CC2CC1CN2c1ccc(N)cc1 -US20120088750A1,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CCNC(=O)Nc1nc2cc(OCc3ccccc3)cc(Br)c2s1>>C=C(OCC)c1cc(OCc2ccccc2)cc2nc(NC(=O)NCC)sc12 -US20150210722A1,1,C#Cc1cc(N)cc(C(=O)NCCN2CCOCC2)c1.CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1>>C#Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)C)nn4-c4cccc(CP(C)(C)=O)c4)c4ccccc34)n2)cc(C(=O)NCCN2CCOCC2)c1 -US20060079522A1,2,Cc1ccc(N)cc1C1CCN(Cc2ccc(Oc3cc(F)c(F)cc3F)cc2)CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1ccc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1C1CCN(Cc2ccc(Oc3cc(F)c(F)cc3F)cc2)CC1 -US20150183809A1,1,COC(=O)[C@H](CCO)O[Si](C)(C)C(C)(C)C.ClCOCc1ccccc1>>COC(=O)[C@H](CCOCOCc1ccccc1)O[Si](C)(C)C(C)(C)C -US20020193402A1,1,C=CCN1C2CCC(O)C1(c1ccccc1)C(C#N)C2.FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1>>C=CCN1[C@H]2CC[C@@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@]1(c1ccccc1)[C@@H](C#N)C2 -US08063234B2,7,O=C(c1ccc(Cl)cc1Cl)C1CC1(F)F>>OC(c1ccc(Cl)cc1Cl)C1CC1(F)F -US20140243302A1,1,COc1ccc2ncc(F)c(CC(O)C34CCC(N)(CC3)CO4)c2n1.O=Cc1cc2c(cn1)OCC(=O)N2>>COc1ccc2ncc(F)c(CC(O)C34CCC(NCc5cc6c(cn5)OCC(=O)N6)(CC3)CO4)c2n1 -US05366972,9,Cc1cc(C(F)(F)F)c(C(N)=O)c(Cl)n1>>Cc1cc(C(F)(F)F)c(N)c(Cl)n1 -US08034810B2,1,COC(=O)CN(Cc1ccc(OC)cc1)S(=O)(=O)c1ccc(O)cc1.FCCCCBr>>COC(=O)CN(Cc1ccc(OC)cc1)S(=O)(=O)c1ccc(OCCCCF)cc1 -US07812022B2,1,Nc1ccc2cnccc2c1.O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Cl)n2)c1)c1c(F)cccc1F>>O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Nc3ccc4cnccc4c3)n2)c1)c1c(F)cccc1F -US07576082B2,3,COc1cc([Mg+])cc(OC)c1.O=C1Nc2cc(Cl)ccc2C1=O>>COc1cc(OC)cc(C2(O)C(=O)Nc3cc(Cl)ccc32)c1 -US08063048B2,3,CON(C)C(=O)c1ccc(C(F)(F)F)c(OCC(F)(F)F)c1.C[Mg+]>>CC(=O)c1ccc(C(F)(F)F)c(OCC(F)(F)F)c1 -US07612212B2,1,BrCc1ccccc1.CC(C)(C)OC(=O)NC(C(=O)O)c1ccc(Br)cc1>>CC(C)(C)OC(=O)NC(C(=O)OCc1ccccc1)c1ccc(Br)cc1 -US06046201,2,CCN1CCN(c2ccc(C(=O)[O-])cn2)CC1.CS(=O)(=O)OCCCCCCCCCCCCN>>CCN1CCN(c2ccc(C(=O)NCCCCCCCCCCCCOS(C)(=O)=O)cn2)CC1 -US20090131437A1,1,CN.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3cc(Cl)ncn3)cc2)cc1>>CNc1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)cc2)ncn1 -US08642619B2,5,CCCOc1ccc(F)cc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCCOc1ccc(F)cc1NC(=O)C(F)(F)F -US20080249301A1,1,COC(=O)c1sc(-n2cnc3ccccc32)cc1O.FC(F)(F)c1ccccc1CBr>>COC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1C(F)(F)F -US06780872B2,9,Cc1ccc(C(=O)O)cc1I>>Cc1ccc(C=O)cc1I -US08188301B2,1,CC(C)Br.OC1(c2ccc(F)c(F)c2)CCNC1>>CC(C)N1CCC(O)(c2ccc(F)c(F)c2)C1 -US04808620,1,CC(C)(C)c1cc(-c2n[nH]c3ncccc23)cc(C(C)(C)C)c1O.CCCCCCCCI>>CCCCCCCCn1nc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2cccnc21 -US08217177B2,3,CC(C)(C)OC(=O)NCc1nnc2ccc(Cl)nn12.CC1(C)OB(c2ccc(N3CCCC3=O)c(F)c2)OC1(C)C>>CC(C)(C)OC(=O)NCc1nnc2ccc(-c3ccc(N4CCCC4=O)c(F)c3)nn12 -US20100041892A1,2,CC(C)Oc1cc(/C=C/C(=O)O)n(Cc2ccc(C(F)(F)F)cc2Cl)n1.COCCCS(N)(=O)=O>>COCCCS(=O)(=O)NC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl -US20070247585A1,7,CCCC=CC1CCC2c3ccc(OCC)c(F)c3OC2C1>>CCCCCC1CCC2c3ccc(OCC)c(F)c3OC2C1 -US20070213321A1,1,FC(F)(F)c1ccc2sc(S)nc2c1.O=C(CCl)N1CCCc2ccccc21>>O=C(CSc1nc2cc(C(F)(F)F)ccc2s1)N1CCCc2ccccc21 -US08093383B2,1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)c[nH]2)CC1.CI>>Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(C(=O)OC(C)(C)C)CC1 -US20040067984A1,8,CC(C)S(=O)(=O)NC1CCCC1O>>CC(C)S(=O)(=O)NC1CCCC1=O -US20090227799A1,1,ClCc1ccc(OCc2ccccc2)cc1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1ccc(OCc2ccccc2)cc1 -US20070060754A1,2,CC(C)N=C=O.CCOCc1nc2c(N)nc3cc(OCCCCCCN)ccc3c2n1CC(C)(C)NC(=O)NC(C)C>>CCOCc1nc2c(N)nc3cc(OCCCCCCNC(=O)NC(C)C)ccc3c2n1CC(C)(C)NC(=O)NC(C)C -US04639526,2,CCCc1nnc(N)s1.CN=C=O>>CCCc1nnc(NC(=O)NC)s1 -US20130217666A1,9,COC(=O)C(C)(O)C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2.N>>CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)C(N)=O -US04294960,2,Nc1nc(C(=NOC2CCCC2)C(=O)O)cs1.O=CO>>O=CNc1nc(C(=NOC2CCCC2)C(=O)O)cs1 -US20150045378A1,6,CCOC(=O)CC(c1cc(OCc2cc(OCC(C)C)c(-c3cc(OC)ccc3F)cn2)ncn1)C1CC1>>COc1ccc(F)c(-c2cnc(COc3cc(C(CC(=O)O)C4CC4)ncn3)cc2OCC(C)C)c1 -US20120220577A1,6,COC(=O)c1cc(OCC(=O)Nc2cccc(OCC(=O)N3CCOCC3)c2)c2c(Cl)cc(Cl)cc2c1>>O=C(COc1cc(C(=O)O)cc2cc(Cl)cc(Cl)c12)Nc1cccc(OCC(=O)N2CCOCC2)c1 -US20080039506A1,7,CC(=O)OCCCS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCCN(C[C@H](O)c3cccnc3)C(=O)OC(C)(C)C)cc2)cc1OCC(C)C>>CC(C)COc1cc(-c2ccc(CCCN(C[C@H](O)c3cccnc3)C(=O)OC(C)(C)C)cc2)ccc1C(=O)NS(=O)(=O)CCCO -US20060258666A1,3,CC1(C)COB(c2ccc(NC(=O)c3nc(C#N)cn3COCC[Si](C)(C)C)c(C3=CCCCC3)c2)OC1.Nc1ccc(Br)cn1>>C[Si](C)(C)CCOCn1cc(C#N)nc1C(=O)Nc1ccc(-c2ccc(N)nc2)cc1C1=CCCCC1 -US20100099681A1,6,COC(=O)c1cc(OC)ccc1Nc1c(-c2ccc3ncnn3c2)c(C)nn1-c1ccccc1C>>COc1ccc(Nc2c(-c3ccc4ncnn4c3)c(C)nn2-c2ccccc2C)c(C(=O)O)c1 -US20040157866A1,7,CC(=O)OCc1ccc(C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2ccccn2)c(-c2ccc(C(F)(F)F)cc2)c1>>O=C(Nc1ccc2c(c1)CCN2C(=O)Cc1ccccn1)c1ccc(CO)cc1-c1ccc(C(F)(F)F)cc1 -US20060094778A1,6,CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1ccc(C(=O)NCC(=O)OC)c(C)c1>>CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1ccc(C(=O)NCC(=O)O)c(C)c1 -US04749407,2,C#CCN.O=S(=O)(Cl)c1cccc(Cl)c1>>C#CCNS(=O)(=O)c1cccc(Cl)c1 -US06992083B2,2,COc1ccc(C2CCOCC2)c2oc(N)nc12.Cc1cc(C(=O)O)ccn1>>COc1ccc(C2CCOCC2)c2oc(NC(=O)c3ccnc(C)c3)nc12 -US20050020830A1,6,Cc1ncc2c(n1)C1CC2CN(C(=O)OC(C)(C)C)C1>>Cc1ncc2c(n1)C1CNCC2C1 -US06268365B1,1,COc1ccc(CCl)cc1.Cc1c(I)c[nH]c(=O)c1[N+](=O)[O-]>>COc1ccc(Cn2cc(I)c(C)c([N+](=O)[O-])c2=O)cc1 -US20050239797A1,6,CN1CCN(c2nccc3cc4c(cc23)N(Cc2ccccc2)CC4)CC1>>CN1CCN(c2nccc3cc4c(cc23)NCC4)CC1 -US07507841B2,9,Cc1c(C)c(NC(=O)CC(C)(C)C)c2c(c1C)C(O)(c1ccc(C(C)C)cc1)C(C)(C)O2>>Cc1c(C)c(NC(=O)CC(C)(C)C)c2c(c1C)C(c1ccc(C(C)C)cc1)C(C)(C)O2 -US20090030003A1,1,CC(C)n1ncc2c(=O)[nH]c([C@@H]3CNC[C@H]3C)nc21.O=Cc1ccnc2cccnc12>>CC(C)n1ncc2c(=O)[nH]c([C@@H]3CN(Cc4ccnc5cccnc45)C[C@H]3C)nc21 -US20060211603A1,4,C#CC(=O)OC.CC(C)C=NO>>COC(=O)c1cc(C(C)C)no1 -US06362336B1,7,Cc1cc(F)c([N+](=O)[O-])cc1O>>Cc1cc(F)c(N)cc1O -US20090275569A1,1,COc1ccc(Cl)c(-c2cc(C)c3nc(N)nnc3c2)c1.O=C(NCCN1CCCC1)c1ccc(Br)cn1>>COc1ccc(Cl)c(-c2cc(C)c3nc(Nc4ccc(C(=O)NCCN5CCCC5)nc4)nnc3c2)c1 -US20120101082A1,2,Cc1cc(C(=O)O)ccc1CC(=O)N1CCN(CC2CCC2)CC1.Cn1ncc2c1Nc1ccccc1NC2>>Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CC(=O)N1CCN(CC2CCC2)CC1 -US20130172341A1,6,COC(=O)C1CCc2c(c(-c3ccncc3)nn2C(C)(C)C)C1>>CC(C)(C)n1nc(-c2ccncc2)c2c1CCC(C(=O)O)C2 -US20120202806A1,1,C1COCCN1.Nc1nc(-c2ccccn2)nc(Cl)c1Cc1ccccc1>>Nc1nc(-c2ccccn2)nc(N2CCOCC2)c1Cc1ccccc1 -US20040152714A1,6,COc1ccc(CNc2nc(C)nc(C)c2Cl)cc1OCc1ccccc1>>COc1ccc(CNc2nc(C)nc(C)c2Cl)cc1O -US20070004774A1,5,O=C(NC1CC(CCOCc2ccccc2)Nc2ccc(C(F)(F)F)cc21)OCc1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NC1CC(CCOCc2ccccc2)N(C(=O)C(F)(F)F)c2ccc(C(F)(F)F)cc21)OCc1ccccc1 -US20080269461A1,3,COc1cc2c(cc1B1OC(C)(C)C(C)(C)O1)c1ccccc1n2CCC(C)CCCC(C)C.COc1cc2c(cc1Br)c1ccccc1n2CCC(C)CCCC(C)C>>COc1cc2c(cc1-c1cc3c4ccccc4n(CCC(C)CCCC(C)C)c3cc1OC)c1ccccc1n2CCC(C)CCCC(C)C -US20050261502A1,1,N#Cc1c(N)nc(Cl)c(C#N)c1-c1ccccc1.OCc1cccnc1>>N#Cc1c(N)nc(OCc2cccnc2)c(C#N)c1-c1ccccc1 -US20110039852A1,3,CCOC(=O)Cc1cc(Cl)cc(B2OC(C)(C)C(C)(C)O2)c1.O=Cc1cc(C(F)(F)F)ccc1Br>>CCOC(=O)Cc1cc(Cl)cc(-c2ccc(C(F)(F)F)cc2C=O)c1 -US06500985B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1ccccc1)C(=O)CCl>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)CCl -US20100016396A1,2,C1CCNC1.COC(=O)[C@H](C)Oc1cc(Sc2c(C(=O)O)c(C)nn2C)c(Cl)cc1Cl>>COC(=O)[C@H](C)Oc1cc(Sc2c(C(=O)N3CCCC3)c(C)nn2C)c(Cl)cc1Cl -US20100249163A1,6,COCCCc1ccc(Cl)c(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(OC)c2ccc(F)c(F)c2)C2CC2)c1>>COCCCc1ccc(Cl)c(CN(C(=O)C2CNCCC2(OC)c2ccc(F)c(F)c2)C2CC2)c1 -US20100135999A1,6,CCCCOC(=O)N1CCN(C(=O)CNC(=O)c2cc(OCC(=O)OCc3ccccc3)c3cc(C)c(C)cc3n2)CC1>>CCCCOC(=O)N1CCN(C(=O)CNC(=O)c2cc(OCC(=O)O)c3cc(C)c(C)cc3n2)CC1 -US05516904,1,CC(C)=CCBr.Sc1ccc(Br)cc1>>CC(C)=CCSc1ccc(Br)cc1 -US06825188B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(Br)c(CNCc2ccc(C(F)(F)F)cc2)c1>>COc1ccc(Br)c(CN(Cc2ccc(C(F)(F)F)cc2)C(=O)OC(C)(C)C)c1 -US20090298899A1,3,N#CCc1cccc(NC(=O)c2cccc(Br)n2)c1.OB(O)c1ccccc1>>N#CCc1cccc(NC(=O)c2cccc(-c3ccccc3)n2)c1 -US20090264445A1,1,CCOC(=O)C=C(C)Cl.Oc1cccc(C(F)(F)F)c1>>CCOC(=O)/C=C(\C)Oc1cccc(C(F)(F)F)c1 -US04067903,1,Nc1ccccc1.Oc1ccc2ccccc2c1>>c1ccc(Nc2ccc3ccccc3c2)cc1 -US20070197621A1,9,CCc1ccc(OCc2ccccc2)c(CC)c1C(O)c1ncc[nH]1>>CCc1ccc(OCc2ccccc2)c(CC)c1Cc1ncc[nH]1 -US20070149542A1,1,CCCI.O=S(=O)(c1cccc(C2CCNCC2)c1F)C(F)(F)F>>CCCN1CCC(c2cccc(S(=O)(=O)C(F)(F)F)c2F)CC1 -US06166006,6,Cc1ccc(-c2ccc3c(c2)C=C(C(=O)OC(C)(C)C)CO3)cc1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CO3)cc1 -US07728144B2,1,COC(=O)CCBr.O=C(Nc1ccccc1-c1ccccc1)OC1CCNCC1>>COC(=O)CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1 -US20140275179A1,6,CCOC(=O)CCc1cc(F)c(OCc2c(-c3ccc4c(c3)CCO4)csc2C(F)(F)F)c(F)c1>>O=C(O)CCc1cc(F)c(OCc2c(-c3ccc4c(c3)CCO4)csc2C(F)(F)F)c(F)c1 -US08153814B2,6,CC(C)(C)OC(=O)N1CC(n2nccc2-c2cc(C(F)(F)F)ccc2O)C1>>Oc1ccc(C(F)(F)F)cc1-c1ccnn1C1CNC1 -US20150141396A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OC1CCC2(CC1)OCCO2>>Cc1ccc(S(=O)(=O)OC2CCC3(CC2)OCCO3)cc1 -US20110059941A1,4,COC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)O)c1.Nc1cccnc1N>>COC[C@H](C)Oc1cc(OCc2ccccc2)cc(-c2nc3cccnc3[nH]2)c1 -US08969345B2,1,C/C(C#N)=C1/c2ccc(CBr)cc2COc2cc(F)ccc21.COCc1nc2c(C(C)(C)O)cccc2[nH]1>>COCc1nc2c(C(C)(C)O)cccc2n1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)C#N -US20090239862A1,9,O=C(OCc1ccccc1)N1CCC(C(=O)O)(c2ccc3ccccc3c2)CC1>>O=CC1(c2ccc3ccccc3c2)CCN(C(=O)OCc2ccccc2)CC1 -US20090062259A1,1,COC(=O)Cc1ccc(-c2cccc(C=O)c2)cc1.c1ccc2c(c1)CNC2>>COC(=O)Cc1ccc(-c2cccc(CN3Cc4ccccc4C3)c2)cc1 -US20120142681A1,1,CC(=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1.NN1CCNC1=O>>C/C(=N\N1CCNC1=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 -US20080039459A1,2,CN(C)CCN.CS(=O)(=O)Cl>>CN(C)CCNS(C)(=O)=O -US20150225411A1,2,C[C@H](N)C(F)(F)F.O=C(O)c1ccc(Br)c(F)c1>>C[C@H](NC(=O)c1ccc(Br)c(F)c1)C(F)(F)F -US20130017194A1,7,CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2)CC1 -US07709471B2,6,CN1C(=O)CCN(C2CCCC2)c2nc(Nc3cc(F)c(C(=O)OC(C)(C)C)cc3Cl)ncc21>>CN1C(=O)CCN(C2CCCC2)c2nc(Nc3cc(F)c(C(=O)O)cc3Cl)ncc21 -US04299830,2,O=C(OC(=O)C1CC1)C1CC1.c1ccc2c(c1)CC1CN2CCN1>>O=C(C1CC1)N1CCN2CC1Cc1ccccc12 -US06696475B2,7,O=c1ncn(-c2ccc(-c3ccccc3)cc2[N+](=O)[O-])[nH]1>>Nc1cc(-c2ccccc2)ccc1-n1cnc(=O)[nH]1 -US08334236B2,7,COC(=O)c1cccnc1Nc1ccc(OC)nc1>>COc1ccc(Nc2ncccc2CO)cn1 -US20090023729A1,1,CCOC(=O)CCCBr.O=C(OCc1ccccc1)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(O)cn1>>CCOC(=O)CCCOc1cnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(=O)OCc2ccccc2)nc1 -US06894050B2,1,CC(C)(C)OC(=O)NCc1cccc(F)c1.Clc1cncc(Cl)n1>>CC(C)(C)OC(=O)N(Cc1cccc(F)c1)c1cncc(Cl)n1 -US20110212956A1,2,CC1NCCc2cccc(N3CCOCC3)c21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2c(cccc2N2CCOCC2)CCN1C(=O)c1cc2ncc(Br)cn2n1 -US20090029903A1,2,CCCCCCNCc1ccc(F)c(C(=O)OC)c1.O=S(=O)(Cl)c1ccc(Br)cc1>>CCCCCCN(Cc1ccc(F)c(C(=O)OC)c1)S(=O)(=O)c1ccc(Br)cc1 -US08415378B2,6,CC(C)CC1CC(=O)CC(=O)N1C(=O)OC(C)(C)C>>CC(C)CC1CC(=O)CC(=O)N1 -US20080139607A1,3,CC1(C)OC(=O)CC(=O)O1.CCCCCCCC(=O)O>>CCCCCCCC(O)=C1C(=O)OC(C)(C)OC1=O -US07375101B2,2,CN(C)c1ccc(N)cc1.CN1C(=O)C(N=C=S)N=C(c2ccccc2)c2cc(Cl)ccc21>>CN(C)c1ccc(NC(=S)NC2N=C(c3ccccc3)c3cc(Cl)ccc3N(C)C2=O)cc1 -US20040010009A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(O)c(F)c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2F)CC1 -US20130281438A1,7,O=[N+]([O-])c1ccccc1S(=O)(=O)NC1CCCCC1>>Nc1ccccc1S(=O)(=O)NC1CCCCC1 -US05885979,2,Nc1ccc(Cl)cc1C(O)c1ccccc1Cl.O=C(O)C(F)(F)F>>O=C(Nc1ccc(Cl)cc1C(O)c1ccccc1Cl)C(F)(F)F -US20080132497A1,2,C1COCCN1.O=C(O)Cc1ccc2c(c1)sc1ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>O=C(Cc1ccc2c(c1)sc1ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)N1CCOCC1 -US08377930B2,2,COC(=O)C(OC)c1ccc2ccccc2c1.NN>>COC(C(=O)NN)c1ccc2ccccc2c1 -US20060128790A1,9,Cc1cc2c(c(C)c1O)C(=O)CC1(CCC1)O2.NO>>Cc1cc2c(c(C)c1O)C(=NO)CC1(CCC1)O2 -US20050032786A1,6,COc1ccc2c(=O)nc(-c3cccc(CCC(=O)OC(C)(C)C)n3)sc2c1>>COc1ccc2c(=O)nc(-c3cccc(CCC(=O)O)n3)sc2c1 -US08003785B2,2,COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C.NCCCN1CCOCC1>>COc1cc(C(=O)NCCCN2CCOCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20140088117A1,6,Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1OCC(C)(CNC(=O)C(F)(F)F)CO1>>Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1OCC(C)(CN)CO1 -US20150218150A1,2,CN1Cc2cc(-c3ccc(-c4cncc(N)c4)s3)ccc2C1=O.COc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(S(=O)(=O)Nc2cncc(-c3ccc(-c4ccc5c(c4)CN(C)C5=O)s3)c2)cc1 -US06211234B1,6,CCOC(=O)CCC(Oc1cc(OCc2ccsc2)cc(F)c1C#N)c1ccccc1C>>Cc1ccccc1C(CCC(=O)O)Oc1cc(OCc2ccsc2)cc(F)c1C#N -US08163728B2,7,CCOC(=O)c1c(C2CCOCC2)noc1C>>Cc1onc(C2CCOCC2)c1CO -US08034812B2,2,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.Cn1nc(C(F)(F)F)cc1C(=O)O>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1NC(=O)c1cc(C(F)(F)F)nn1C -US20120098417A1,3,Clc1cc(Cl)ncn1.OB(O)c1ccc2ccccc2c1>>Clc1cc(-c2ccc3ccccc3c2)ncn1 -US04426522,1,O=C(Cl)Cc1ccccc1Cl.O=C1CNN(Cc2ccc(Cl)cc2)C(=O)N1>>O=C1CN(C(=O)Cc2ccccc2Cl)N(Cc2ccc(Cl)cc2)C(=O)N1 -US20100076224A1,2,CC(C)(C)OC(=O)N[C@@H](CCSC(F)(F)F)C(=O)O.Nc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCSC(F)(F)F)C(=O)Nc1ccccc1 -US20140336108A1,1,COC(=O)c1cc2nccc(Cl)c2s1.Nc1cccc(O)c1>>COC(=O)c1cc2nccc(Oc3cccc(N)c3)c2s1 -US20070049604A1,1,CCCc1cc(C=O)nn1C(C)(C)C.NCCN1CCN(c2ccccc2)CC1>>CCCc1cc(CNCCN2CCN(c3ccccc3)CC2)nn1C(C)(C)C -US07074805B2,2,N#Cc1ccc(CO)cc1.O=C=Nc1cccc2cnccc12>>N#Cc1ccc(COC(=O)Nc2cccc3cnccc23)cc1 -US20040092402A1,3,COc1cc(B(O)O)c(F)cc1Cl.FC(F)(F)c1ncnc(Cl)c1Cl>>COc1cc(-c2ncnc(C(F)(F)F)c2Cl)c(F)cc1Cl -US20110009454A1,1,CCCCCCCI.Nc1ncccc1C(=O)NCc1cccc(O)c1F>>CCCCCCCOc1cccc(CNC(=O)c2cccnc2N)c1F -US04798897,1,O=C1CCN(S(=O)(=O)c2cccc3cnccc23)CC1.[NH4+]>>NC1CCN(S(=O)(=O)c2cccc3cnccc23)CC1 -US04853384,2,Fc1c(F)c(F)c(OC2(c3ccccc3)CCNCC2)c(F)c1F.O=CO>>O=CN1CCC(Oc2c(F)c(F)c(F)c(F)c2F)(c2ccccc2)CC1 -US06803369B1,7,COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1>>CC(C)(C)OC(=O)N1CCN[C@H](CO)C1 -US20110224203A1,5,Nc1c[nH]nc1-c1nc2ccccc2[nH]1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1c[nH]nc1-c1nc2ccccc2[nH]1)C(F)(F)F -US20150038528A1,2,CC(C)(C)OC(=O)C1(CN)CCS(=O)CC1.COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O>>CC(C)(C)OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCS(=O)CC1 -US20150246894A1,6,CCOC(=O)CN1C(=O)OC(c2ccc(F)cc2)(c2ccc(F)cc2)[C@@H]1c1ccccc1>>O=C(O)CN1C(=O)OC(c2ccc(F)cc2)(c2ccc(F)cc2)[C@@H]1c1ccccc1 -US05055474,9,C=CC(c1ccccc1)c1cc(C)c2c(c1O)C(=O)CC2.NO>>C=CC(c1ccccc1)c1cc(C)c2c(c1O)C(=NO)CC2 -US05852011,2,CN(C)CCN.O=C(O)c1cc([N+](=O)[O-])ccc1Cl>>CN(C)CCNC(=O)c1cc([N+](=O)[O-])ccc1Cl -US20060025466A1,1,CC(=O)CCl.O=[N+]([O-])c1ccc2[nH]ncc2c1>>CC(=O)Cn1ncc2cc([N+](=O)[O-])ccc21 -US08071592B2,7,O=[N+]([O-])c1cc(F)cc2c1OCCO2>>Nc1cc(F)cc2c1OCCO2 -US20140194418A1,9,COC(=O)c1ccc(Nc2nc(SC)nc(Cl)c2C(N)=O)c(OC)c1.[NH4+]>>COC(=O)c1ccc(Nc2nc(SC)nc(N)c2C(N)=O)c(OC)c1 -US06787543B2,1,COC(=O)[C@@H]1CCCCN1.O=Cc1ccccc1>>COC(=O)[C@@H]1CCCCN1Cc1ccccc1 -US20120129843A1,1,C1CN(C2CC2)CCN1.CC(=O)c1ccc(Cl)nc1>>CC(=O)c1ccc(N2CCN(C3CC3)CC2)nc1 -US05134111,9,Oc1cccc2ccccc12>>c1ccc2ccccc2c1 -US06794389B2,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](CNC(=O)C(F)(F)F)CC1>>N[C@H]1CC[C@@H](CNC(=O)C(F)(F)F)CC1 -US20140243375A1,1,CC(C)(C)OC(=O)NC1CONC1=O.CCBr>>CCN1OC[C@@H](NC(=O)OC(C)(C)C)C1=O -US20110319414A1,1,BrCc1ccccn1.CC(C)Oc1ccc(Nc2nc(=O)[nH]c(=O)n2Cc2ccc(Cl)cc2)cc1F>>CC(C)Oc1ccc(Nc2nc(=O)n(Cc3ccccn3)c(=O)n2Cc2ccc(Cl)cc2)cc1F -US04539410,2,CCOC(=O)CCCCCCCn1c(-n2ccnc2)c(C)c2ccccc21.CN>>CNC(=O)CCCCCCCn1c(-n2ccnc2)c(C)c2ccccc21 -US20140315944A1,6,CCOC(=O)CC1Cc2ccc(OCc3cccc(Cl)c3)cc2N(C(=O)OC(C)(C)C)C1=O>>CCOC(=O)CC1Cc2ccc(OCc3cccc(Cl)c3)cc2NC1=O -US06008198,7,CC(C)(C)C(=O)Nc1ccccc1-c1c2nc(c(-c3ccccc3NC(=O)C(C)(C)C)c3cc(C=O)c([nH]3)c(-c3ccccc3NC(=O)C(C)(C)C)c3nc(c(-c4ccccc4NC(=O)C(C)(C)C)c4ccc1[nH]4)C=C3)C=C2>>CC(C)(C)C(=O)Nc1ccccc1-c1c2nc(c(-c3ccccc3NC(=O)C(C)(C)C)c3cc(CO)c([nH]3)c(-c3ccccc3NC(=O)C(C)(C)C)c3nc(c(-c4ccccc4NC(=O)C(C)(C)C)c4ccc1[nH]4)C=C3)C=C2 -US20120172396A1,6,COc1ccc(NC(=O)NC2C3CC4CC(C3)CC2C4)c(C)c1>>Cc1cc(O)ccc1NC(=O)NC1C2CC3CC(C2)CC1C3 -US08686048B2,3,COc1ccc(Cl)c(B(O)O)c1.Nc1ccc(Br)c(F)c1>>COc1ccc(Cl)c(-c2ccc(N)cc2F)c1 -US20090209522A1,6,COc1ccc(C(C)(C)C)cc1Oc1nc(C(=O)Nc2c(OC)nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc2OC)cs1>>COc1ccc(C(C)(C)C)cc1Oc1nc(C(=O)Nc2c(OC)nc(NCCNC(C)C)nc2OC)cs1 -US20100105655A1,1,COC(=O)CBr.C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1>>COC(=O)CN1CCN(C(=O)OC(C)(C)C)C[C@H]1C -US07709647B2,2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.OC1CCCCC1>>O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCCCC1 -US20110245310A1,7,CC(C)c1nc2c(n1Cc1ccc(Cl)c(Cl)c1)C(=O)CCCC2>>CC(C)c1nc2c(n1Cc1ccc(Cl)c(Cl)c1)C(O)CCCC2 -US20120022078A1,7,O=Cc1ccc(F)nc1>>OCc1ccc(F)nc1 -US06951879B2,1,Cc1sc2cc(OCCOS(C)(=O)=O)ccc2c1-c1ccc(C(F)(F)F)cc1.c1c[nH]cn1>>Cc1sc2cc(OCCn3ccnc3)ccc2c1-c1ccc(C(F)(F)F)cc1 -US20150005167A1,4,COC(=O)CCC(=O)Nc1ccc(C#N)cn1.[N-]=[N+]=[N-]>>COC(=O)CCC(=O)Nc1ccc(-c2nnn[nH]2)cn1 -US20140206681A1,2,CC1(C)CC2CCC(C(=O)O)CN2C1=O.NCc1nccnc1Cl>>CC1(C)CC2CCC(C(=O)NCc3nccnc3Cl)CN2C1=O -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)Nc2ncc(C(F)(F)F)cc2Cl)cc1.FC(F)(F)c1ccc(CBr)cc1>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(C(F)(F)F)cc2)c2ncc(C(F)(F)F)cc2Cl)cc1 -US07655679B2,2,COc1ccc(-c2csc(N)n2)cc1.N#Cc1ccc(CC(=O)O)cc1>>COc1ccc(-c2csc(NC(=O)Cc3ccc(C#N)cc3)n2)cc1 -US20130196974A1,1,Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(Cl)c2c1.O[C@@H]1CCNC1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(N3CC[C@@H](O)C3)c2c1 -US07579359B2,2,CCCCC(=O)Cl.Nc1cnc2ccccc2c1Cl>>CCCCC(=O)Nc1cnc2ccccc2c1Cl -US20080300275A1,6,CC(C)(C)OC(=O)CCOCCc1ccc(Br)cc1>>O=C(O)CCOCCc1ccc(Br)cc1 -US05665719,6,COC(=O)c1ccc(OCC2CCN(C(=O)OC(C)(C)C)CC2)cc1OC>>COc1cc(OCC2CCN(C(=O)OC(C)(C)C)CC2)ccc1C(=O)O -US20060160832A1,6,COC(=O)c1cc2c(Oc3ccc(Cl)c([N+](=O)[O-])c3)ccnc2cc1OC>>COc1cc2nccc(Oc3ccc(Cl)c([N+](=O)[O-])c3)c2cc1C(=O)O -US20120108583A1,6,COC(=O)c1cc2nc(Nc3c(Cl)cccc3Cl)[nH]c2c2nc(C3CC3)oc12>>O=C(O)c1cc2nc(Nc3c(Cl)cccc3Cl)[nH]c2c2nc(C3CC3)oc12 -US05905079,1,Cc1nnc2c(C(C)Br)ccnn12.Oc1ccc(Cl)cc1>>Cc1nnc2c(C(C)Oc3ccc(Cl)cc3)ccnn12 -US20100016396A1,9,COC(=O)[C@H](C)Oc1cc(Oc2c(C)c(C)nn2C)c(Cl)cc1C=O.NO>>COC(=O)[C@H](C)Oc1cc(Oc2c(C)c(C)nn2C)c(Cl)cc1/C=N/O -US08329726B2,2,COC(=O)CC(=O)Cl.Nc1ccccc1>>COC(=O)CC(=O)Nc1ccccc1 -US20060025414A1,6,CC(C)(C)OC(=O)N1CCCC1c1cc(-c2cccc(Cl)c2)on1>>Clc1cccc(-c2cc(C3CCCN3)no2)c1 -US20080262050A1,2,CC1(C)CCc2cc(O)c(N3CC(=O)NS3(=O)=O)cc2C1.O=C(Cl)c1ccccc1>>CC1(C)CCc2cc(OC(=O)c3ccccc3)c(N3CC(=O)NS3(=O)=O)cc2C1 -US08497281B2,2,COc1ccc2c(c1C)[C@H]1CCCN[C@H]1C2.O=C(O)c1ccc2[nH]cnc2c1>>COc1ccc2c(c1C)[C@H]1CCCN(C(=O)c3ccc4[nH]cnc4c3)[C@H]1C2 -US20140142074A1,2,CS(=O)(=O)Cl.CS(=O)(=O)Oc1ccc(C[C@H](N)C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1>>CS(=O)(=O)N[C@@H](Cc1ccc(OS(C)(=O)=O)cc1)C(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 -US06093716,1,Brc1ccc(Br)nc1.C1CNCCN1>>Brc1ccc(N2CCNCC2)nc1 -US06469042B1,1,FCCBr.Oc1ccc(Cl)cc1Br>>FCCOc1ccc(Cl)cc1Br -US20120041002A1,1,CCO.Nc1cc(Cl)c(C(F)(F)F)cc1[N+](=O)[O-]>>CCOc1cc(N)c([N+](=O)[O-])cc1C(F)(F)F -US05202335,7,O=C(O)/C(=C/c1cccs1)CC(=O)N1C[C@@H]2CCCC[C@@H]2C1>>O=C(O)C(CC(=O)N1C[C@@H]2CCCC[C@@H]2C1)Cc1cccs1 -US20120071481A1,6,CCOC(=O)c1noc(-c2ccc(C(F)(F)F)cc2)c1CNC(C)C>>CC(C)NCc1c(C(=O)O)noc1-c1ccc(C(F)(F)F)cc1 -US07538107B2,1,N#C[S-].O=C(CBr)c1ccc(Br)cc1>>N#CSCC(=O)c1ccc(Br)cc1 -US20070088036A1,7,O=C(O)C1(c2ccc(Cl)cc2)CCNCC1>>OCC1(c2ccc(Cl)cc2)CCNCC1 -US07550500B2,8,O[C@H]1CC2CCC1N(Cc1ccccc1)C2>>O=C1CC2CCC1N(Cc1ccccc1)C2 -US08906944B2,6,Cc1ccc(F)c(NC(=O)c2ccc(F)c(Oc3ccnc(-c4cc(C(=O)NCCNC(=O)OC(C)(C)C)c[nH]4)c3)c2)c1>>Cc1ccc(F)c(NC(=O)c2ccc(F)c(Oc3ccnc(-c4cc(C(=O)NCCN)c[nH]4)c3)c2)c1 -US05616637,1,CN1C(C)(C)CC(O)CC1(C)C.ClCC1CO1>>CN1C(C)(C)CC(OCC2CO2)CC1(C)C -US20120149721A1,2,CC(=O)Cl.Cc1[nH]c2c(-c3cc(F)ccc3OCC3CC3)ncnc2c1C(=O)NC1CCNCC1>>CC(=O)N1CCC(NC(=O)c2c(C)[nH]c3c(-c4cc(F)ccc4OCC4CC4)ncnc23)CC1 -US20150045409A1,2,CCC1(CN)COCOC1.CCCCCC/C=C/C(=O)O>>CCCCCC/C=C/C(=O)NCC1(CC)COCOC1 -US20090192162A1,6,CCOC(=O)COc1ccc(Sc2cc(C#Cc3ccc(S(C)(=O)=O)cc3)cc(Oc3cccc(C(F)(F)F)c3)c2)cc1C>>Cc1cc(Sc2cc(C#Cc3ccc(S(C)(=O)=O)cc3)cc(Oc3cccc(C(F)(F)F)c3)c2)ccc1OCC(=O)O -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1cccc2cccnc12>>CCCC(C(=O)O)c1c(C)nc(N2CCCCC2)nc1-c1cccc2cccnc12 -US20120121540A1,6,CC(C)(C)OC(=O)N1CC=C(c2cccs2)C1>>C1=C(c2cccs2)CNC1 -US07589232B2,2,CC1(C)OC(=O)c2cc(NCc3ccc(C#Cc4ccc(Cl)cc4)cc3)ccc2O1.O=C(Cl)c1ccno1>>CC1(C)OC(=O)c2cc(N(Cc3ccc(C#Cc4ccc(Cl)cc4)cc3)C(=O)c3ccno3)ccc2O1 -US20140142085A1,2,NC(=O)c1cc(-c2cccnc2[C@@H](N)Cc2cc(F)cc(F)c2)ccc1F.O=C(O)Cn1nc(C(F)(F)F)c2cc(F)ccc21>>NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3cc(F)ccc32)ccc1F -US08273766B2,6,COC(=O)C1Cc2cc(F)ccc2CN1Cc1ccccc1>>O=C(O)C1Cc2cc(F)ccc2CN1Cc1ccccc1 -US07030128B2,3,CCCC[Sn](CCCC)(CCCC)c1ccco1.CC[Si](CC)(CC)OC(C)(C)c1ccn2c(-c3ccnc(Cl)n3)cnc2n1>>CC[Si](CC)(CC)OC(C)(C)c1ccn2c(-c3ccnc(-c4ccco4)n3)cnc2n1 -US07572809B2,1,COc1ccc(O)cc1.COc1cccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc12>>COc1ccc(Oc2nc(Nc3cc(C)[nH]n3)cc3c(OC)cccc23)cc1 -US07053086B2,3,Cc1cc(CCC(=O)O)c(C=O)[nH]1.O=C1Cc2c(cccc2C2CCNCC2)N1>>Cc1cc(CCC(=O)O)c(C=C2C(=O)Nc3cccc(C4CCNCC4)c32)[nH]1 -US20090275590A1,1,Cn1c2c(c3ccc(Br)cc31)CN(C(=O)OC(C)(C)C)CC2.O=c1cc(OCc2ccccn2)cc[nH]1>>Cn1c2c(c3ccc(-n4ccc(OCc5ccccn5)cc4=O)cc31)CN(C(=O)OC(C)(C)C)CC2 -US20100076000A1,1,CS(=O)(=N[N+](=O)[O-])c1cccc(N)c1.C[C@H](CO)Nc1nc(Cl)ncc1Br>>C[C@H](CO)Nc1nc(Nc2cccc(S(C)(=O)=N[N+](=O)[O-])c2)ncc1Br -US20140142085A1,6,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncccc1-c1ccc(Cl)cc1>>N[C@@H](Cc1cc(F)cc(F)c1)c1ncccc1-c1ccc(Cl)cc1 -US05952306,6,CC(C)(C)OC(=O)[C@H](CNC(=O)CNC(=O)CCCc1csc(N)n1)NS(=O)(=O)c1ccccc1>>Nc1nc(CCCC(=O)NCC(=O)NC[C@H](NS(=O)(=O)c2ccccc2)C(=O)O)cs1 -US20130310384A1,1,CCOC(=O)c1ccc(CBr)nc1.CC[C@H](NS(=O)(=O)c1ccc(Cl)cc1)c1ccccc1>>CCOC(=O)c1ccc(CN([C@@H](CC)c2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)nc1 -US20130039906A1,3,Brc1cc2c(I)nn(C3CCCCO3)c2cn1.OB(O)c1ccccc1F>>Fc1ccccc1-c1nn(C2CCCCO2)c2cnc(Br)cc12 -US05081121,4,COc1cc(NC(=O)C2CC2)c(C(C)=O)cc1OC>>COc1cc2[nH]c(C3CC3)cc(=O)c2cc1OC -US20100048581A1,7,CCN(CC)CC(C#N)(c1ccccc1)c1ccccc1>>CCN(CC)CC(CN)(c1ccccc1)c1ccccc1 -US20070254869A1,2,CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCNc2c(C)cc(C(F)(F)F)cc21.CC(C)OC(=O)Cl>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2c(C)cc(C(F)(F)F)cc21 -US08329686B2,1,BrCc1ccccc1.O=C1Nc2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc2C1=O>>O=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 -US03966701,6,CC(C)(C)OC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)OCc1ccccc1>>N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)OCc1ccccc1 -US06291464B1,2,CC(=O)N1CCN(N)CC1.O=C(Cl)c1cccs1>>CC(=O)N1CCN(NC(=O)c2cccs2)CC1 -US05412101,1,CCCCc1nc(SC)c(C(=O)OCC)[nH]1.COC(=O)c1ccccc1-c1ccc(CBr)cc1>>CCCCc1nc(SC)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1 -US07687640B2,1,CC(=O)CCl.COC(=O)c1ccc(NC=O)c(OC)c1>>COC(=O)c1ccc(N(C=O)CC(C)=O)c(OC)c1 -US20140065136A1,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.FC(F)(F)C1COc2c(nc(Cl)nc2N2CCOCC2)O1>>Nc1ncc(-c2nc3c(c(N4CCOCC4)n2)OCC(C(F)(F)F)O3)cn1 -US20120258950A1,6,CCOC(=O)Cc1ccn2ccnc2c1>>O=C(O)Cc1ccn2ccnc2c1 -US04018915,1,CC(C)(C)OC(=O)CCl.NCc1ccccc1>>CC(C)(C)OC(=O)CNCc1ccccc1 -US20070155805A1,7,CCCCC(=CC(=O)OCC)c1oc2cc(C)ccc2c1C>>CCCCC(CC(=O)OCC)c1oc2cc(C)ccc2c1C -US20090048286A1,2,CC(=O)OC(C)=O.COC(=O)c1sc2ncc(N)cc2c1OCC(=O)OC(C)(C)C>>COC(=O)c1sc2ncc(NC(C)=O)cc2c1OCC(=O)OC(C)(C)C -US20040167131A1,2,CC(C)(C)OC(=O)NC1(C(=O)O)COC(c2ccccc2)OC1.Nc1ccc(Br)cc1>>CC(C)(C)OC(=O)NC1(C(=O)Nc2ccc(Br)cc2)COC(c2ccccc2)OC1 -US20110224155A1,7,CC(C)Nc1cccc([N+](=O)[O-])c1C#N>>CC(C)Nc1cccc(N)c1C#N -US20030130235A1,6,c1ccc(CN2CC[C@@H](N3CCCCC3)C2)cc1>>C1CCN([C@@H]2CCNC2)CC1 -US20100022541A1,2,COC(=O)CNCc1ccccn1.O=C(O)c1nc(-c2ccccc2)oc1CCl>>COC(=O)CN(Cc1ccccn1)C(=O)c1nc(-c2ccccc2)oc1CCl -US08314109B2,6,CCOC(=O)c1cn2cc(-c3csc(NC(=O)OC(C)(C)C)n3)ccc2n1>>CC(C)(C)OC(=O)Nc1nc(-c2ccc3nc(C(=O)O)cn3c2)cs1 -US06380239B1,7,NC(=O)CCC(C(=O)O)N1C(=O)c2cccc([N+](=O)[O-])c2C1=O>>NC(=O)CCC(C(=O)O)N1C(=O)c2cccc(N)c2C1=O -US08232273B2,1,BrCc1ccccc1.Oc1ccc(Br)cc1F>>Fc1cc(Br)ccc1OCc1ccccc1 -US05268401,1,CC1(C)CC(=O)CC(C)(C)N1.NCCCN1CCOCC1>>CC1(C)CC(NCCCN2CCOCC2)CC(C)(C)N1 -US06310208B1,1,CCCBr.Cc1cc(C)c2c(c1)C1CNCCC1CC2=O>>CCCN1CCC2CC(=O)c3c(C)cc(C)cc3C2C1 -US20090054411A1,1,CN1CCNCC1.COCCOc1cc([N+](=O)[O-])ccc1Cl>>COCCOc1cc([N+](=O)[O-])ccc1N1CCN(C)CC1 -US20090118257A1,2,COC(=O)CN.Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2>>COC(=O)CNC(=O)C1(C)CCc2c(C)c(O)c(C)c(C)c2O1 -US20050107616A1,2,CC(C)(C)[C@H](O)Cn1cnc(Cc2ccccc2)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)[C@@H](Cn1cnc(Cc2ccccc2)c1)OC(=O)Oc1ccc([N+](=O)[O-])cc1 -US20150119435A1,9,CC(C)(C)c1ccc(OCCOCCOCCN=[N+]=[N-])cc1>>CC(C)(C)c1ccc(OCCOCCOCCN)cc1 -US20120197027A1,1,COc1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2cc1O.OCCN1CCCCC1>>COc1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2cc1OCCN1CCCCC1 -US20120316193A1,3,CN(C)C=O.Clc1ccc(-n2cccn2)cc1>>O=Cc1cnn(-c2ccc(Cl)cc2)c1 -US08119676B2,6,COc1ccc(S(=O)(=O)n2c(=O)n(C(C(=O)N3CCN(C4CCN(C(=O)OC(C)(C)C)CC4)CC3)c3ccccc3)c3cc(Cl)ccc32)cc1>>COc1ccc(S(=O)(=O)n2c(=O)n(C(C(=O)N3CCN(C4CCNCC4)CC3)c3ccccc3)c3cc(Cl)ccc32)cc1 -US20090312310A1,2,CC[C@@H]1CC[C@@H](C(=O)O)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1.CN(C)[C@H]1CCNC1>>CCC1CCC(C(=O)N2CC[C@H](N(C)C)C2)N1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1 -US06979690B2,8,CC(C)(C)OC(=O)N1CCC(CCC(O)c2ccc(NC(=O)C(C)(C)C)nc2F)CC1>>CC(C)(C)OC(=O)N1CCC(CCC(=O)c2ccc(NC(=O)C(C)(C)C)nc2F)CC1 -US08450304B2,1,Cc1ccc(C2(O)CCC(=O)CC2)cn1.O=C(CNC(=O)c1cc(F)cc(C(F)(F)F)c1)NC1CNC1>>Cc1ccc(C2(O)CCC(N3CC(NC(=O)CNC(=O)c4cc(F)cc(C(F)(F)F)c4)C3)CC2)cn1 -US03992440,1,CC(=O)Nc1ccc(S)cc1.NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl>>CC(=O)Nc1ccc(Sc2c([N+](=O)[O-])cc(C(=O)O)cc2S(N)(=O)=O)cc1 -US08198099B2,2,O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.OCCCI>>O=C1NC2CSC(CCCCC(=O)OCCCI)C2N1 -US05108486,2,CCN(CC)c1c(Cl)cc(N=C=S)cc1Cl.CNN>>CCN(CC)c1c(Cl)cc(NC(=S)N(C)N)cc1Cl -US09090564B2,2,CCN1CCNCC1.CCc1nccc(-c2ccc(C(=O)O)c(F)c2)c1C#Cc1ccc(NC)nc1>>CCc1nccc(-c2ccc(C(=O)N3CCN(CC)CC3)c(F)c2)c1C#Cc1ccc(NC)nc1 -US20080015191A1,1,COc1cc(N)cc(OC)c1OC.O=C1CCc2ccc(Oc3cncc(Cl)n3)cc21>>COc1cc(Nc2cncc(Oc3ccc4c(c3)C(=O)CC4)n2)cc(OC)c1OC -US20150057271A1,7,COc1cc(C(F)(F)F)ccc1N1C(=O)COc2cc([N+](=O)[O-])ccc21>>COc1cc(C(F)(F)F)ccc1N1C(=O)COc2cc(N)ccc21 -US06239131B1,6,Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(NC(=O)OC(C)(C)C)CN2C(=O)OCc1ccccc1>>Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(N)CN2C(=O)OCc1ccccc1 -US08642585B2,3,Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C)c1Br.Cc1cc(Br)nc(C)n1>>Cc1cc(-c2cc(C)c(Br)c(C)c2)nc(C)n1 -US08586604B2,2,N[C@@H]1CC[C@@H](C(F)(F)F)CC1.O=C(Cl)c1ccc(Cl)nc1Cl>>O=C(N[C@@H]1CC[C@@H](C(F)(F)F)CC1)c1ccc(Cl)nc1Cl -US20010025041A1,2,O=S(=O)(Cl)c1ccccc1Cl.Oc1cc(O)c2ccccc2c1>>O=S(=O)(Oc1cc(O)c2ccccc2c1)c1ccccc1Cl -US20150232463A1,3,CC(C)OC(=O)C(=O)Cl.Cc1nc(C)c(Br)c(Cl)c1Br>>Cc1nc(C)c(C(=O)C(=O)OC(C)C)c(Cl)c1Br -US20140371269A1,6,CO[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1nccs1>>CO[C@@H]1CCNC[C@H]1c1nccs1 -US20120214806A1,6,C=CCCOc1ccc(C(=O)OC)nc1>>C=CCCOc1ccc(C(=O)O)nc1 -US20100029689A1,6,CCOc1cc(N(Cc2cncnc2)c2ccc(C(=O)OC(C)(C)C)cc2)ccc1OC(F)F>>CCOc1cc(N(Cc2cncnc2)c2ccc(C(=O)O)cc2)ccc1OC(F)F -US20070112000A1,6,CC(C)(C)OC(=O)N1CCCC(C(=O)c2cccc(F)c2)C1>>O=C(c1cccc(F)c1)C1CCCNC1 -US06262082B1,1,CC(C)(C)OC(=O)CBr.O=[N+]([O-])c1cc(Cl)c(O)c(Cl)c1>>CC(C)(C)OC(=O)COc1c(Cl)cc([N+](=O)[O-])cc1Cl -US20120077793A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)[C@@H]1Cc2ccc(O)cc2CN1>>CC(C)(C)OC(=O)N1Cc2cc(O)ccc2C[C@H]1C(=O)O -US20140051679A1,3,O=C(NC(c1ccsc1)C1CCC1)c1ccc2[nH]nc(I)c2c1.OB(O)c1ccc(N2CCOCC2)cc1>>O=C(NC(c1ccsc1)C1CCC1)c1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1 -US20090227588A1,1,CCOC(=O)c1ccc(=O)[nH]c1.COCCBr>>CCOC(=O)c1ccc(=O)n(CCOC)c1 -US20090270361A1,6,COC(=O)c1ccc(Cc2c(C)nn(-c3ccc(C#N)cc3)c2C)cc1>>Cc1nn(-c2ccc(C#N)cc2)c(C)c1Cc1ccc(C(=O)O)cc1 -US20090312381A1,2,NC1(c2cccc(Cl)c2)CCC1.O=C(O)Cn1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O>>O=C(Cn1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O)NC1(c2cccc(Cl)c2)CCC1 -US08309718B2,2,C[C@H]1CNC[C@@H](C)O1.O=S(=O)(Cl)Cl>>C[C@H]1CN(S(=O)(=O)Cl)C[C@@H](C)O1 -US20110076291A1,2,C[C@H]1CCCN1.O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2>>C[C@@H]1CCCN1C(=O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2 -US20150252044A1,3,O=C(NCCCn1ccnc1)c1ccc2cncc(Br)c2n1.OB(O)c1ccncc1>>O=C(NCCCn1ccnc1)c1ccc2cncc(-c3ccncc3)c2n1 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2ccccn2)c1.CC(C)(C)OC(=O)Nc1ccc(C#Cc2ccc(F)cc2)cc1N>>CC(C)(C)OC(=O)Nc1ccc(C#Cc2ccc(F)cc2)cc1NC(=O)CC(=O)c1cccc(-c2ccccn2)c1 -US07727988B2,6,COC(CCn1cc(-c2cc(C)cnc2F)c(=O)[nH]c1=O)OC>>Cc1cnc(F)c(-c2cn(CCC=O)c(=O)[nH]c2=O)c1 -US07989477B2,9,NC(=O)c1cc(Oc2ccc(N(Cc3ccc(F)cc3)C(=O)C3(C(N)=O)CC3)cc2F)ccn1>>NC(=O)C1(C(=O)N(Cc2ccc(F)cc2)c2ccc(Oc3ccnc(N)c3)c(F)c2)CC1 -US07754886B2,1,NCCBr.Sc1ccc(Cl)cc1>>NCCSc1ccc(Cl)cc1 -US20120065066A1,3,C1=CCCC=C1.O=C1C=CC(=O)C1>>O=C1CC(=O)C2C3C=CC(CC3)C12 -US20080095711A1,1,CCCCCCCBr.OCCCCCCCO>>CCCCCCCOCCCCCCCO -US20080261941A1,1,Cc1cc(O)cc(Br)c1.FC(F)(F)c1ccc(Cl)nc1>>Cc1cc(Br)cc(Oc2ccc(C(F)(F)F)cn2)c1 -US20080090806A1,9,[N-]=[N+]=Nc1cc(F)cnc1N>>Nc1cc(F)cnc1N -US07820680B2,6,CCOC(=O)CC1CN(C(=O)OCc2ccccc2)CC(=O)N1Cc1ccc(F)cc1>>O=C(O)CC1CN(C(=O)OCc2ccccc2)CC(=O)N1Cc1ccc(F)cc1 -US20120040954A1,4,CC(=O)N1CCCN(c2ccc(C=O)cc2)CC1.COc1cc(N)c(C(N)=O)c(OC)c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCCN(C(C)=O)CC4)cc3)nc2c1 -US20110059961A1,3,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2NC(=O)c2csc(Br)n2)C1.OB(O)c1ccccc1F>>CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2NC(=O)c2csc(-c3ccccc3F)n2)C1 -US20140155419A1,1,CCOC(=O)Cc1ccc(O)cc1.Cc1ncccc1Br>>CCOC(=O)Cc1ccc(Oc2cccnc2C)cc1 -US06156761,6,COc1ccc(Br)c2c1C(=O)CC(C)C2>>CC1CC(=O)c2c(O)ccc(Br)c2C1 -US20060217424A1,1,CI.N#Cc1ccc(O)cc1F>>COc1ccc(C#N)c(F)c1 -US07250410B2,1,CI.COc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2>>COc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2C -US20130196974A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1CN(Cc2ccccc2)CC12COC2>>CC(C)(C)OC(=O)NC1CN(Cc2ccccc2)CC12COC2 -US07504522B2,2,CC(C)(C)N=C=O.FC(F)(F)c1ccccc1C(OC1CNC1)c1ccc(Cl)cc1>>CC(C)(C)NC(=O)N1CC(OC(c2ccc(Cl)cc2)c2ccccc2C(F)(F)F)C1 -US06090837,2,N#Cc1ccc(C(=O)Cl)cc1.NCCCCO>>N#Cc1ccc(C(=O)NCCCCO)cc1 -US20140288046A1,1,CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1.OC[C@@H]1NCC[C@H]1O>>CC(C)(C)c1nc(N2CC[C@@H](O)[C@@H]2CO)c2nnn(Cc3ccccc3Cl)c2n1 -US20040229870A1,1,CCOc1ccc(CCN)cc1OC.Cc1cc(C)c(-n2cnc3c(NCCCl)cc(C)nc32)c(C)c1>>CCOc1ccc(CCNCCNc2cc(C)nc3c2ncn3-c2c(C)cc(C)cc2C)cc1OC -US20100105655A1,2,COc1cc(N2CCNCC2)ccc1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1.O=C(O)CO>>COc1cc(N2CCN(C(=O)CO)CC2)ccc1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1 -US05061804,6,CS(=O)(=O)O[C@@H]1C[C@@H](COCC(=O)NC(N)=O)N(C(=O)OCc2ccccc2)C1>>CS(=O)(=O)O[C@H]1CN[C@H](COCC(=O)NC(N)=O)C1 -US07179823B1,1,CCOC(=O)CCc1c[nH]nc1-c1ccccc1.Fc1ccccc1COc1ccc2cc(CCl)ccc2c1>>CCOC(=O)CCc1cn(Cc2ccc3cc(OCc4ccccc4F)ccc3c2)nc1-c1ccccc1 -US08440651B2,9,Clc1nc(N2CCOCC2)c2nc(CBr)ccc2n1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc2nc(Cl)nc(N3CCOCC3)c2n1 -US08129403B2,7,Cc1nc(N[C@@H](CO)c2ccc(F)cc2)nc(Nc2cc(C3CC3)[nH]n2)c1[N+](=O)[O-]>>Cc1nc(N[C@@H](CO)c2ccc(F)cc2)nc(Nc2cc(C3CC3)[nH]n2)c1N -US20140142122A1,1,COC(=O)CCCBr.Oc1ccc(Cl)cc1>>COC(=O)CCCOc1ccc(Cl)cc1 -US07074801B1,1,BrCc1ccccc1.CNS(=O)(=O)c1ccc(-c2ncnc3ccc(-c4cn(C(c5ccccc5)(c5ccccc5)c5ccccc5)nc4-c4ccc(F)cc4)cc23)s1>>CN(Cc1ccccc1)S(=O)(=O)c1ccc(-c2ncnc3ccc(-c4cn(C(c5ccccc5)(c5ccccc5)c5ccccc5)nc4-c4ccc(F)cc4)cc23)s1 -US08536183B2,3,CB1OB(C)OB(C)O1.C[C@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2Br)CCN1C(=O)OC(C)(C)C>>Cc1cc(C(F)(F)F)ccc1S(=O)(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](C)C1 -US20100130737A1,6,COC(=O)[C@H](Cc1ccc(OCc2ccc(C#N)cc2)cc1)NC(=O)c1cc2cc(-c3ccc(Cl)cc3)ccc2s1>>N#Cc1ccc(COc2ccc(C[C@H](NC(=O)c3cc4cc(-c5ccc(Cl)cc5)ccc4s3)C(=O)O)cc2)cc1 -US06376503B1,6,COc1ccccc1N1CCC2(CC1)OCCO2>>COc1ccccc1N1CCC(=O)CC1 -US20100098634A1,3,COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1F.Nc1nc2ccc(Br)cc2s1>>COc1ccc(-c2ccc3nc(N)sc3c2)cc1F -US06384065B1,3,CC(C)CC=C1CCC2(CC1)SCC(=O)N2CCC(=O)O.O=Cc1ccccc1>>CC(C)CC=C1CCC2(CC1)SC(=Cc1ccccc1)C(=O)N2CCC(=O)O -US09156827B2,1,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1.OCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(Cc2c(OCc3ccccc3)ccc3c2OCC3=O)CC1 -US20110212956A1,2,Cc1n[nH]cc1-c1cccc2c1C(C)NCC2.O=C(O)c1cc2ncc(Br)cn2n1>>Cc1n[nH]cc1-c1cccc2c1C(C)N(C(=O)c1cc3ncc(Br)cn3n1)CC2 -US08304434B2,6,CC(C)(C)OC(=O)N1CCC(C(C)(C)S(=O)(=O)c2cccc(C(F)(F)F)n2)CC1>>CC(C)(C1CCNCC1)S(=O)(=O)c1cccc(C(F)(F)F)n1 -US07652015B2,2,O=C(Cl)c1c(F)cccc1F.O=[N+]([O-])c1ccnc(OC2CCNCC2)c1>>O=C(c1c(F)cccc1F)N1CCC(Oc2cc([N+](=O)[O-])ccn2)CC1 -US20120077812A1,3,CC(C)(C)OC(=O)N1CCC(COc2ccc(Cl)nn2)CC1.CS(=O)(=O)c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)N1CCC(COc2ccc(-c3ccc(S(C)(=O)=O)cc3)nn2)CC1 -US20070219210A1,4,CCOC(=O)C(=O)CC(=O)c1cc(C)ccn1.NNc1ccc(Cl)nn1>>CCOC(=O)c1cc(-c2cc(C)ccn2)n(-c2ccc(Cl)nn2)n1 -US05998409,2,CCOC(=O)Cc1ccccc1N.O=C(Cl)CCCCCl>>CCOC(=O)Cc1ccccc1NC(=O)CCCCCl -US08916560B2,6,COC(=O)c1ccc2nc(-c3ccncc3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccncc1 -US20080096903A1,7,CC(=O)CCCn1c(Cc2cc3c(cc2I)OCO3)nc2c(N)nc(F)nc21>>CC(O)CCCn1c(Cc2cc3c(cc2I)OCO3)nc2c(N)nc(F)nc21 -US04795751,9,CN1CCN(c2c(F)c(F)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1.N>>CN1CCN(c2c(F)c(N)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 -US08143261B2,1,CC(C)(C)OC(=O)NCCN.Nc1nc2nc(SCc3cccc(F)c3F)nc(Cl)c2s1>>CC(C)(C)OC(=O)NCCNc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 -US20060194811A1,3,CC1CCCN(C2CCN(c3ncc(Br)c(NCc4c(F)cccc4F)n3)CC2)C1.OB(O)c1ccc(F)cc1F>>CC1CCCN(C2CCN(c3ncc(-c4ccc(F)cc4F)c(NCc4c(F)cccc4F)n3)CC2)C1 -US20090062530A1,1,COC(=O)CCc1ccc(O)c(Br)c1.Ic1ccccc1>>COC(=O)CCc1ccc(Oc2ccccc2)c(Br)c1 -US04086421,8,CNC(=O)c1c(-c2ccccc2)noc1CC(O)c1ccc(C)cc1>>CNC(=O)c1c(-c2ccccc2)noc1CC(=O)c1ccc(C)cc1 -US03944600,8,CSc1ccc(CC2C(C)=Cc3cc(F)ccc32)cc1.OO>>CC1=Cc2cc(F)ccc2C1Cc1ccc(S(C)=O)cc1 -US20100292214A1,2,C[C@@H](COC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1)N(Cc1ccccc1)Cc1ccccc1.O=S(=O)(Cl)c1ccc(F)cc1>>C[C@@H](COC(=O)N1CCC(n2c(=O)n(S(=O)(=O)c3ccc(F)cc3)c3ccccc32)CC1)N(Cc1ccccc1)Cc1ccccc1 -US06255276B1,7,CC1=CCCCCCCC(=O)OCCCCC1>>CC1CCCCCCCC(=O)OCCCCC1 -US07820658B2,6,CCOC(=O)c1cc2c(-c3cc(OCc4ccccc4)c(Cl)cc3Cl)nc(N)nc2s1>>Nc1nc(-c2cc(OCc3ccccc3)c(Cl)cc2Cl)c2cc(C(=O)O)sc2n1 -US05344843,1,BrCc1ccc2ccccc2c1.COC(=O)C(=O)c1ccc(O)cc1>>COC(=O)C(=O)c1ccc(OCc2ccc3ccccc3c2)cc1 -US07528132B2,9,COc1ccc(Cn2nc(C)c3cc(Br)ccc32)cc1.[C-]#N>>COc1ccc(Cn2nc(C)c3cc(C#N)ccc32)cc1 -US20090270625A1,2,CC(=O)Cl.O=C(N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@H]2[C@@H]1c1ccccc1N[C@H]2c1ccccc1)c1ccccc1>>CC(=O)N1c2ccccc2[C@H]2[C@@H](CCN2C(=O)[C@H]2CCCC[C@H]2NC(=O)c2ccccc2)[C@@H]1c1ccccc1 -US08354394B2,7,CC(=O)CCCCON=[N+]([O-])N(C)C(C)(C)C>>C[C@@H](O)CCCCON=[N+]([O-])N(C)C(C)(C)C -US20020049322A1,2,CS(=O)(=O)Cl.Nc1ccc2c(c1)C(=O)NC2=O>>CS(=O)(=O)Nc1ccc2c(c1)C(=O)NC2=O -US20130317074A1,2,Cc1ccc(N)c(O)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Oc2cc(C)ccc2N)cc1 -US04731443,6,COC(=O)CON=C(C(C)=O)C(=O)OC(C)(C)C>>COC(=O)CON=C(C(C)=O)C(=O)O -US04017534,6,CCCCCC(C)(O)CC[C@H]1CC2OCCOC2[C@@H]1CCCCCCC(=O)OCC>>CCCCCC(C)(O)CC[C@H]1CC2OCCOC2[C@@H]1CCCCCCC(=O)O -US06924300B2,6,COC(=O)CC/C(=N\OCc1ccc(OCc2csc(-c3ccccc3)n2)cc1)c1ccccc1>>O=C(O)CC/C(=N\OCc1ccc(OCc2csc(-c3ccccc3)n2)cc1)c1ccccc1 -US07244722B2,2,CCCCO.CS(=O)(=O)Cl>>CCCCOS(C)(=O)=O -US06252082B1,6,COC(=O)Cn1c(C)cc(S(=O)(=O)c2ccccc2)c(N)c1=O>>Cc1cc(S(=O)(=O)c2ccccc2)c(N)c(=O)n1CC(=O)O -US08008501B2,2,Cc1cc(O)c2ccccc2n1.Cc1onc(-c2ccccc2)c1C(=O)Cl>>Cc1cc(OC(=O)c2c(-c3ccccc3)noc2C)c2ccccc2n1 -US07855216B2,6,CCOC(=O)c1c(Nc2ccc(I)cc2F)c2cnccc2n1Cc1ccc(OC)cc1>>COc1ccc(Cn2c(C(=O)O)c(Nc3ccc(I)cc3F)c3cnccc32)cc1 -US20090227575A1,3,Cn1ccc2c3nc(Cl)nc(N4CCOCC4)c3ccc21.NC(=O)c1cccc(B(O)O)c1>>Cn1ccc2c3nc(-c4cccc(C(N)=O)c4)nc(N4CCOCC4)c3ccc21 -US05711964,1,CCCCCCCCCCCCCCCCOC(CBr)C(O)CCCCCCCCCCCCCCCC.C[S-]>>CCCCCCCCCCCCCCCCOC(CSC)C(O)CCCCCCCCCCCCCCCC -US04479000,2,COc1cc([N+](=O)[O-])ccc1N.O=C(Cl)OCc1ccccc1>>COc1cc([N+](=O)[O-])ccc1NC(=O)OCc1ccccc1 -US05179112,7,COC(=O)c1ccc(Cn2nc(OCc3ccccc3)c3ccc([N+](=O)[O-])cc32)c(OC)c1>>COC(=O)c1ccc(Cn2nc(OCc3ccccc3)c3ccc(N)cc32)c(OC)c1 -US20080242698A1,2,NCc1ccccc1.O=C(Cl)N1c2ccccc2CCc2ccccc21>>O=C(NCc1ccccc1)N1c2ccccc2CCc2ccccc21 -US07355042B2,6,CCOC(=O)c1ccc(C(CCN(C)C)c2ccccn2)cc1>>CN(C)CCC(c1ccc(C(=O)O)cc1)c1ccccn1 -US20100234429A1,6,COC(=O)c1cccc(CNC(=O)c2cccnc2SCCCc2ccc(F)cc2)c1>>O=C(O)c1cccc(CNC(=O)c2cccnc2SCCCc2ccc(F)cc2)c1 -US20070232768A1,2,COC(=O)C(C)Cl.OCCNCCO>>CC(Cl)C(=O)N(CCO)CCO -US05037824,8,Cc1nc(-c2ccccc2)cc(-c2ccc(CO)o2)c1C(=O)NCCN1CCOCC1>>Cc1nc(-c2ccccc2)cc(-c2ccc(C=O)o2)c1C(=O)NCCN1CCOCC1 -US20110190256A1,6,CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1>>CC(C)(Oc1ccc(Cl)cc1)C(=O)O -US06384051B1,10,CC(=O)N(c1cccc(Br)c1)c1c(C#N)cnc2c(C)cc([N+](=O)[O-])cc12.O=C1CCC(=O)N1Br>>CC(=O)N(c1cccc(Br)c1)c1c(C#N)cnc2c(CBr)cc([N+](=O)[O-])cc12 -US20090258917A1,1,CC(C)Br.Cc1ccc2oc(-c3cc(Br)ccc3O)nc2c1>>Cc1ccc2oc(-c3cc(Br)ccc3OC(C)C)nc2c1 -US20150175623A1,3,CCOC(=O)[C@@H](Cc1ccccc1OC)Oc1ncnc2sc(-c3ccco3)c(Br)c12.Cc1c(B2OC(C)(C)C(C)(C)O2)ccc(O)c1F>>CCOC(=O)[C@@H](Cc1ccccc1OC)Oc1ncnc2sc(-c3ccco3)c(-c3ccc(O)c(F)c3C)c12 -US04284829,6,CCCCCCC(C)(C)c1ccc(CCC(C)=O)c(OCc2ccccc2)c1>>CCCCCCC(C)(C)c1ccc(CCC(C)=O)c(O)c1 -US20150031920A1,7,CC(=O)c1ccccc1>>CC(O)c1ccccc1 -US20060084643A1,1,C=O.CC(C)c1nc2c(s1)Nc1ccccc1N=C2N1CCNC(CCO)C1>>CC(C)c1nc2c(s1)Nc1ccccc1N=C2N1CCN(C)[C@@H](CCO)C1 -US20150025056A1,2,COC(=O)Cl.COC(=O)[C@H]1C[C@H](OC)CN[C@@H]1C(=O)N1CCN(c2ccccc2)CC1>>COC(=O)[C@H]1C[C@H](OC)CN(C(=O)OC)[C@@H]1C(=O)N1CCN(c2ccccc2)CC1 -US20150210703A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1nccn1N>>CCOC(=O)c1nccn1NC(=O)OC(C)(C)C -US20120157436A1,2,COC(=O)c1ncccc1O.NN>>NNC(=O)c1ncccc1O -US07579323B1,2,CC(C)(CC(=O)O)c1ccccc1.CC(C)[C@H]1COC(=O)N1>>CC(C)[C@H]1COC(=O)N1C(=O)CC(C)(C)c1ccccc1 -US20150191495A1,6,COC(=O)CCOc1cc(C)c(Br)c(C)c1>>Cc1cc(OCCC(=O)O)cc(C)c1Br -US05473063,8,O=C(OC[C@H]1CC(O)C[C@@H]1COC(=O)c1ccccc1)c1ccccc1>>O=C1C[C@H](COC(=O)c2ccccc2)[C@@H](COC(=O)c2ccccc2)C1 -US05041143,1,NCCN.O=C1OCCN1c1ccc(F)c([N+](=O)[O-])c1>>NCCNc1ccc(N2CCOC2=O)cc1[N+](=O)[O-] -US08211914B2,2,Nc1ccc(N2CCC(c3cccc(C(F)(F)F)c3)CC2)nc1.O=C(Cl)c1nc(-c2ccccc2)oc1C(F)(F)F>>O=C(Nc1ccc(N2CCC(c3cccc(C(F)(F)F)c3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US20110124636A1,2,O=C(NC[C@@H]1C[C@@H]2C[C@@H]2N1)c1cccc2c1OCCO2.O=C(O)c1ccccc1-c1ccccc1F>>O=C(NC[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)c1ccccc1-c1ccccc1F)c1cccc2c1OCCO2 -US20060100262A1,6,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCN(C(=O)CN(C)C)Cc1cc(F)ccc1-3>>CN(C)CC(=O)N1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccc(F)cc2C1 -US20130274469A1,2,C1CSCCN1.Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)N2CCSCC2)cn1 -US20120094964A1,1,BrCc1ccccc1.COC(=O)c1ccc(S(=O)(=O)Nc2ncc(C(F)(F)F)cc2Br)cc1>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Br)cc1 -US20150051225A1,2,COc1ccccc1-c1nc(C2CC(C)(C)OC(C)(C)C2)c[nH]1.O=S(=O)(Cl)C1CC1>>COc1ccccc1-c1nc(C2CC(C)(C)OC(C)(C)C2)cn1S(=O)(=O)C1CC1 -US08399451B2,7,N#Cc1ccc(C(=O)CBr)cc1>>N#Cc1ccc(C(O)CBr)cc1 -US20040235822A1,1,ClCc1ccccn1.O=[N+]([O-])c1ccc(S)cc1>>O=[N+]([O-])c1ccc(SCc2ccccn2)cc1 -US20100298295A1,1,CNC(=O)c1ccc(-c2cc(OC)c(Nc3ncc(C(F)(F)F)c(Cl)n3)cc2C)cc1.Cc1cc(N)n[nH]1>>CNC(=O)c1ccc(-c2cc(OC)c(Nc3ncc(C(F)(F)F)c(Nc4cc(C)[nH]n4)n3)cc2C)cc1 -US20140206622A1,9,NN.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>NNC(=O)OCC1c2ccccc2-c2ccccc21 -US20040132752A1,1,CNCCO.O=[N+]([O-])c1ccc(F)cc1>>CN(CCO)c1ccc([N+](=O)[O-])cc1 -US20050176699A1,3,CN1C(=O)CN=C(Cl)c2cc(Cl)ccc21.OB(O)c1cccnc1>>CN1C(=O)CN=C(c2cccnc2)c2cc(Cl)ccc21 -US04354026,9,Clc1ccc(-c2ccncc2)nn1.NN>>NNc1ccc(-c2ccncc2)nn1 -US20110230497A1,2,CC(=O)Cl.CCOC(=O)C(C)(C)C1CCNCC1>>CCOC(=O)C(C)(C)C1CCN(C(C)=O)CC1 -US20150094295A1,3,CN(C1COC1)C(C)(C)C=O.N#CCC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3F)c3c(N)ncnc32)C1>>CN(C1COC1)C(C)(C)C=C(C#N)C(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3F)c3c(N)ncnc32)C1 -US04806547,6,c1ccc(CN2CCc3ccccc3C2CN2CCCC2)cc1>>c1ccc2c(c1)CCNC2CN1CCCC1 -US08609848B2,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)c2c1OC(C)(C)C2.O=S(=O)(Cl)c1cccc2cccnc12>>COc1ccc(C2=NN(C3CCN(S(=O)(=O)c4cccc5cccnc45)CC3)C(=O)C2(C)C)c2c1OC(C)(C)C2 -US05561150,9,CC1=C2C=c3c(cnn3CC(C)N=[N+]=[N-])=C2CC=C1>>CC1=C2C=c3c(cnn3CC(C)N)=C2CC=C1 -US08420851B2,6,CCOC(=O)CN(C(=O)OCC)c1cc(Cl)c(Oc2ccc(O)c(C(C)CC)c2)c(Cl)c1>>CCOC(=O)N(CC(=O)O)c1cc(Cl)c(Oc2ccc(O)c(C(C)CC)c2)c(Cl)c1 -US05296495,6,COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1>>CC(C)(C)c1csc(-c2cc3cc(O)ccc3o2)n1 -US20110092703A1,6,CC(C)c1ccc(N2CCN(Cc3ccccc3)CC2COc2ccc(Cl)cc2)cc1>>CC(C)c1ccc(N2CCNCC2COc2ccc(Cl)cc2)cc1 -US08188301B2,1,FC(F)(F)CCI.OC1(c2cccc(F)c2F)CCNC1>>OC1(c2cccc(F)c2F)CCN(CCC(F)(F)F)C1 -US20070161645A1,1,Cc1nc(Cl)cc(Cl)n1.OCCN1CCNCC1>>Cc1nc(Cl)cc(N2CCN(CCO)CC2)n1 -US20140228361A1,9,CCc1nnc2n1CCNC2Cl>>CCc1nnc2n1CCNC2 -US20050038072A1,1,CCOc1cccc(OC)c1CO.O=C1CCNCC1C(c1ccccc1)c1ccccc1>>CCOc1cccc(OC)c1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1 -US06583159B1,1,CN.O=C1CCN(CCCOCCc2ccc(F)cc2)CC1>>CNC1CCN(CCCOCCc2ccc(F)cc2)CC1 -US20090156610A1,2,NCCN1CCCC1.O=C1CC(c2cccc(Cl)c2)C2(C(=O)Nc3cc(Cl)ccc32)C(c2cc(Br)ccc2Oc2ccc(C(=O)F)cc2)N1>>O=C1CC(c2cccc(Cl)c2)C2(C(=O)Nc3cc(Cl)ccc32)C(c2cc(Br)ccc2Oc2ccc(C(=O)NCCN3CCCC3)cc2)N1 -US05438064,2,CCOC(=O)c1cnc2cc(Cl)ccc2c1Nc1ccc(C(=O)O)cc1.NC1CCN(Cc2ccccc2)CC1>>CCOC(=O)c1cnc2cc(Cl)ccc2c1Nc1ccc(C(=O)NC2CCN(Cc3ccccc3)CC2)cc1 -US08993779B2,3,Cn1c(=O)n(CC(C)(C)C)c2ccc(Br)cc21.OB(O)c1ccccc1>>Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3ccccc3)cc21 -US07229987B2,2,COC(=O)c1ccc(OCCCN(C)C)cc1.NN>>CN(C)CCCOc1ccc(C(=O)NN)cc1 -US09120749B2,1,CC(=O)c1cnc2ccc(Br)cc2c1Cl.CN(C)C[C@@H]1CC[C@@H](N)CC1>>CC(=O)c1cnc2ccc(Br)cc2c1N[C@@H]1CC[C@@H](CN(C)C)CC1 -US08710224B2,1,CCBr.O=C(OCc1ccccc1)N1CCN(C[C@@H]2CCCNC2)CC1>>CCN1CCC[C@@H](CN2CCN(C(=O)OCc3ccccc3)CC2)C1 -US08399465B2,1,Clc1nc2ncccc2s1.OCc1cc2ncc(O)cc2o1>>OCc1cc2ncc(Oc3nc4ncccc4s3)cc2o1 -US06531491B1,1,Nc1cccc(Cl)c1[N+](=O)[O-].OCCS>>Nc1cccc(SCCO)c1[N+](=O)[O-] -US20130274244A1,1,CNC.Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(CC=O)ccn45)cccc32)n1>>Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(CCN(C)C)ccn45)cccc32)n1 -US20110312945A1,4,CC(=O)CC1CCCC1=O.CCOC(=O)CN>>CCOC(=O)Cn1c(C)cc2c1CCC2 -US20110034507A1,6,COC(=O)c1cccc(-c2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3c2)n1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2cc(-c3cccc(C(=O)O)n3)ccc2c1 -US05356889,7,CC(=O)OCc1ccc2c(c1)C(=O)c1ccc(Br)cc1-2>>O=C1c2cc(CO)ccc2-c2cc(Br)ccc21 -USRE030241,7,CCCCCC1CC1CC(=O)Oc1ccc(C(=O)CNC(C)(C)C)cc1OC(=O)CC1CC1CCCCC>>CCCCCC1CC1CC(=O)Oc1ccc(C(O)CNC(C)(C)C)cc1OC(=O)CC1CC1CCCCC -US05420275,1,CCOC(=O)c1c(Cl)nc(-c2ccccc2)c([N+](=O)[O-])c1C(=O)OCC.c1nc[nH]n1>>CCOC(=O)c1c(-n2cncn2)nc(-c2ccccc2)c([N+](=O)[O-])c1C(=O)OCC -US07652143B2,6,CC(C)[C@@H](NCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C>>CC(C)[C@@H](NCCN)C(=O)OC(C)(C)C -US20140275108A1,6,COC(=O)C(CN1C(=O)c2ccccc2C1=O)(C(=O)OC)N1CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C(CN)(C(=O)OC)N1CCN(C(=O)OC(C)(C)C)CC1 -US20090264401A1,6,CCCSc1ncc(C(=O)OCC)c(N2C[C@H](C)O[C@H](C)C2)n1>>CCCSc1ncc(C(=O)O)c(N2C[C@H](C)O[C@H](C)C2)n1 -US20100256356A1,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.COc1ccc(Cn2nc(I)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(-c3cnn(C(=O)OC(C)(C)C)c3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1 -US06455520B1,1,CN1CCNCC1.Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1NC(=O)c1cccc(Cl)c1[N+](=O)[O-]>>Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1NC(=O)c1cccc(N2CCN(C)CC2)c1[N+](=O)[O-] -US20090281074A1,2,COC(=O)C(=O)Cl.Cc1cc(N)ccc1Cl>>COC(=O)C(=O)Nc1ccc(Cl)c(C)c1 -US04849422,1,Clc1ccc(Cl)nn1.OCC(O)CN1CCNCC1>>OCC(O)CN1CCN(c2ccc(Cl)nn2)CC1 -US20040138462A1,6,CCOC(=O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1Cl>>O=C(O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1Cl -US20090163488A1,2,Cc1nn(C)cc1C(=O)O.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)ccc1F>>Cc1nn(C)cc1C(=O)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)ccc1F -US07547680B2,7,CCOC(=O)COc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1>>OCCOc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 -US20090291942A1,1,CC(C)N1CCNCC1C.CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CO)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CN2CCN(C(C)C)C(C)C2)cc1 -US20070293515A1,6,Cc1ccc(C(F)(F)c2noc([C@H]3CC[C@H](NC(=O)OC(C)(C)C)C3)n2)cc1>>Cc1ccc(C(F)(F)c2noc([C@H]3CC[C@H](N)C3)n2)cc1 -US08026257B2,1,C=O.Cn1ncc2cc(C(F)(F)F)cc(COCC3(c4ccccc4)CCNCC3)c21>>CN1CCC(COCc2cc(C(F)(F)F)cc3cnn(C)c23)(c2ccccc2)CC1 -US05145857,7,COCc1c(C(C)C)nc(N(C)C)c(C(=O)OC)c1-c1ccc(F)cc1>>COCc1c(C(C)C)nc(N(C)C)c(CO)c1-c1ccc(F)cc1 -US20090048282A1,5,CCOC(=O)C(F)(F)F.c1ccc2c(c1)CCN2>>O=C(N1CCc2ccccc21)C(F)(F)F -US20130210809A1,6,CNC(=O)c1c(-c2csc(Nc3nccc(C)n3)n2)cnn1Cc1ccc(OC)cc1>>CNC(=O)c1[nH]ncc1-c1csc(Nc2nccc(C)n2)n1 -US04766128,2,CC(=O)Cl.CCN(CC)C(=O)N[C@H]1C[C@@H]2c3cc([N+](=O)[O-])cc4[nH]cc(c34)C[C@H]2N(C)C1>>CCN(CC)C(=O)N[C@H]1C[C@@H]2c3cc([N+](=O)[O-])cc4c3c(cn4C(C)=O)C[C@H]2N(C)C1 -US20090226398A1,3,CC(C)Cc1ccc(B(O)O)cc1.Fc1cccc(-c2nc3cnn(Cc4ccc(Cl)nn4)cc-3n2)c1F>>CC(C)Cc1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)nn2)cc1 -US20020013309A1,1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2.O=C(c1ccccc1)c1cncc(Br)c1>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1cncc(C(=O)c2ccccc2)c1 -US20030096856A1,7,COc1ccc(S(=O)(=O)N(C)c2cc(OC)c(OC)c(OC)c2)cc1[N+](=O)[O-]>>COc1ccc(S(=O)(=O)N(C)c2cc(OC)c(OC)c(OC)c2)cc1N -US20030065176A1,6,COC(=O)c1ccccc1-c1ccc(C#N)cc1>>N#Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20120232096A1,1,COc1c(C)c(N2CCNCC2)c(C)c2c1OC(C)C2.COc1ccc(Br)cc1F>>COc1ccc(N2CCN(c3c(C)c4c(c(OC)c3C)OC(C)C4)CC2)cc1F -US20130203714A1,1,FC(F)(F)c1nnc2ccc(Cl)nn12.Oc1ccc(C2CCNCC2)cc1>>Oc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US20090099184A1,1,CO.O=C(NCc1ccc(Cl)cc1Cl)c1ccnc(F)c1>>COc1cc(C(=O)NCc2ccc(Cl)cc2Cl)ccn1 -US04851425,6,CCOC(=O)C(OC)c1nn(-c2ccc(Cl)cc2)c2c1CCCC2>>COC(C(=O)O)c1nn(-c2ccc(Cl)cc2)c2c1CCCC2 -US09156840B2,6,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccccc4)CC3)C2=O)c1>>O=C(O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccccc4)CC3)C2=O)c1 -US20120285538A1,4,CCC1(CC)c2cc(N)ccc2-c2ccc(Br)cc21.ICCCCCI>>CCC1(CC)c2cc(Br)ccc2-c2ccc(N3CCCCC3)cc21 -US07625908B2,1,Cc1cc(Nc2ncnc3cccc(F)c23)ccc1O.NCCO>>Cc1cc(Nc2ncnc3cccc(OCCN)c23)ccc1O -US05990106,1,CC(C)(C)OC(=O)NC12CCC1CNC2.O=C(O)c1cn(C2CC2)c2c(Cl)c(F)c(F)cc2c1=O>>CC(C)(C)OC(=O)NC12CCC1CN(c1c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c1Cl)C2 -US20140275523A1,6,CCOC(=O)c1c[nH]c(-c2ccc(Cl)cc2F)n1>>O=C(O)c1c[nH]c(-c2ccc(Cl)cc2F)n1 -US20120238539A1,1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1cc([N+](=O)[O-])c(N)cc1F>>CC(C)(C)OC(=O)N1CCN(c2cc(N)c([N+](=O)[O-])cc2C#N)CC1 -US05908840,2,CN(C)CCN.O=C(O)c1cccn2c(=O)c3ccc(Br)cc3nc12>>CN(C)CCNC(=O)c1cccn2c(=O)c3ccc(Br)cc3nc12 -US08501746B2,2,Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)O.NCc1ccncc1>>Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1ccncc1 -US05929085,7,O=c1c2ccccc2cc2n1CCCC2>>O=C1c2ccccc2CC2CCCCN12 -US20090324581A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cccc2cc[nH]c12>>Cc1cccc2ccn(C(=O)OC(C)(C)C)c12 -US20080090854A1,2,COC(=O)C1(N)CCCC1.O=C(O)c1ccc2ccccc2c1O>>COC(=O)C1(NC(=O)c2ccc3ccccc3c2O)CCCC1 -US04816452,4,CCOC(=O)/C(=N\OC1CCCCCCC1)C(=O)CBr.NC(N)=S>>CCOC(=O)/C(=N\OC1CCCCCCC1)c1csc(N)n1 -US20090285782A1,1,Fc1ccc(-c2ccc3ncnc(Cl)c3c2)cc1.NC1CCCCC1>>Fc1ccc(-c2ccc3ncnc(NC4CCCCC4)c3c2)cc1 -US07645769B2,1,Brc1cnc2[nH]ccc2c1.Sc1ccccc1>>c1ccc(Sc2cnc3[nH]ccc3c2)cc1 -US05223633,2,CC1(C)COC(C)(C)N1.CCOC(=O)Cl>>CCOC(=O)N1C(C)(C)COC1(C)C -USRE042376E1,1,COCCNCCOC.COc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCBr>>COCCN(CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc2cc1OC)CCOC -US20040259884A1,1,CCOc1ccc(C(F)(F)F)cc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)c1ccc(CCl)cc1.OCCN1CCNCC1>>CCOc1ccc(C(F)(F)F)cc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)c1ccc(CN2CCN(CCO)CC2)cc1 -US20150259351A1,2,Cc1cc(C)c(CN)c(O)n1.Cc1ccccc1-n1cc(C(=O)O)c2ccccc21>>Cc1cc(C)c(CNC(=O)c2cn(-c3ccccc3C)c3ccccc23)c(O)n1 -US20140314669A1,6,COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1ccc(OCCF)cc1>>CC(C)(C)OC(=O)N1CCC(CCC(=O)N2CCC[C@@H](C(=O)NC(CC(=O)O)c3ccc(OCCF)cc3)C2)CC1 -US05041460,2,COc1cc(C(=O)O)ccc1Cc1cn(C)c2ccc(CC(C)NC(=O)N(C)C)cc12.NS(=O)(=O)c1ccccc1Cl>>COc1cc(C(=O)NS(=O)(=O)c2ccccc2Cl)ccc1Cc1cn(C)c2ccc(CC(C)NC(=O)N(C)C)cc12 -US20060211695A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(Oc2ccnc3[nH]cc(I)c23)c(F)c1>>CC(C)(C)OC(=O)n1cc(I)c2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc21 -US20140275030A1,2,CC(=O)Cl.Cc1noc(C)c1-c1ccc2nc(N3CCCNCC3)n3c2c1OC[C@@H]3c1ccccn1>>CC(=O)N1CCCN(c2nc3ccc(-c4c(C)noc4C)c4c3n2[C@@H](c2ccccn2)CO4)CC1 -US20080021010A1,6,CN1CCCCC1C1(CNC(=O)c2c(F)ccc(F)c2Cl)CN(C(=O)OC(C)(C)C)C1>>CN1CCCCC1C1(CNC(=O)c2c(F)ccc(F)c2Cl)CNC1 -US04769387,3,CC(=O)Cl.c1ccc2c(c1)oc1ccccc12>>CC(=O)c1ccc2c(c1)oc1ccccc12 -US20080113961A1,1,COC(=O)C1CNC1.Cc1cc(CO)sc1-c1noc(-c2ccc(Oc3ccccc3)c(F)c2)n1>>COC(=O)C1CN(Cc2cc(C)c(-c3noc(-c4ccc(Oc5ccccc5)c(F)c4)n3)s2)C1 -US07064218B2,2,CCCNCCN.CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2[nH]1>>CCCNCCNC(=O)c1cc2cc([N+](=O)[O-])ccc2[nH]1 -US07897607B2,3,Brc1cccc(Br)n1.Cc1cc(C)c(B(O)O)c(C)c1>>Cc1cc(C)c(-c2cccc(Br)n2)c(C)c1 -US07122550B2,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O.Clc1cncc(NCc2ccc(Cl)c(Cl)c2)n1>>COc1cc(-c2cncc(NCc3ccc(Cl)c(Cl)c3)n2)ccc1O -US20060019997A1,4,C#CCO.[N-]=[N+]=Nc1cccc(Cl)c1>>OCc1cn(-c2cccc(Cl)c2)nn1 -US20140134235A1,1,NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=Cc1cnc2ccccc2c1N(CC1CC1)CC1CC1>>FC(F)(F)c1cc(CNCc2cnc3ccccc3c2N(CC2CC2)CC2CC2)cc(C(F)(F)F)c1 -US20090215776A1,3,CN1CCN(Cc2cccc(B(O)O)c2)CC1.Cc1cccc(-c2cc(-c3cncc(Br)c3)cc(NC3CC3)n2)n1>>Cc1cccc(-c2cc(-c3cncc(-c4cccc(CN5CCN(C)CC5)c4)c3)cc(NC3CC3)n2)n1 -US20100168101A1,2,COC(=O)c1ccc(CNC(=O)c2ccc(Cl)cc2)cc1.NN>>NNC(=O)c1ccc(CNC(=O)c2ccc(Cl)cc2)cc1 -US20050245592A1,6,CCOc1cc(CBr)c(C#N)cc1C(=O)N(C)C(=O)OC(C)(C)C>>CCOc1cc(CBr)c(C#N)cc1C(=O)NC -US20130131043A1,2,CS(=O)(=O)Cl.OC1CCCCCC1>>CS(=O)(=O)OC1CCCCCC1 -US20120121540A1,6,COC(=O)C(NC(=O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl)c1cccs1>>O=C(NC(C(=O)O)c1cccs1)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl -US20140155444A1,2,CC(C)[C@H]1c2ccc(F)cc2C(F)(F)C[C@]1(O)CC(=O)O.CNCCCc1nc2ccccc2[nH]1>>CC(C)[C@H]1c2ccc(F)cc2C(F)(F)C[C@]1(O)CC(=O)N(C)CCCc1nc2ccccc2[nH]1 -US20140142083A1,1,C=O.COC(=O)c1cc(C2CNC2)cc(N(C)C2CCOCC2)c1C>>COC(=O)c1cc(C2CN(C)C2)cc(N(C)C2CCOCC2)c1C -US20040138160A1,6,C[Si](C)(C)O[C@@H](CC#N)COCc1ccccc1>>N#CC[C@H](O)COCc1ccccc1 -US05719150,6,CN1CCN(CCOCC(OC2CCCCO2)c2cccc3ccccc23)CC1>>CN1CCN(CCOCC(O)c2cccc3ccccc23)CC1 -US20140296246A1,3,CC(C)(C)C[Mg+].CCOc1nc2c(C(=O)c3ccccn3)cc(-c3c(C)noc3C)cc2[nH]1>>CCOc1nc2c(C(O)(CC(C)(C)C)c3ccccn3)cc(-c3c(C)noc3C)cc2[nH]1 -US05552550,7,CCOC(=O)c1cc(OC)c2c(OC(C)C)ccc(Br)c2c1>>COc1cc(CO)cc2c(Br)ccc(OC(C)C)c12 -US05166170,7,Nc1ccc(Cl)cc1-c1cc2ccccc2[nH]1>>Nc1ccc(Cl)cc1C1Cc2ccccc2N1 -US08629275B2,7,CC1(C)O[C@@H]2C=C(F)[C@@H](n3cnc4c(N)ncc(F)c43)[C@@H]2O1>>CC1(C)O[C@@H]2CC(F)[C@@H](n3cnc4c(N)ncc(F)c43)[C@@H]2O1 -US20070179178A1,2,Cc1onc(-c2ccccc2)c1-c1cn2ccc(C(=O)O)cc2n1.NCC1CC1>>Cc1onc(-c2ccccc2)c1-c1cn2ccc(C(=O)NCC3CC3)cc2n1 -US20100093706A1,2,COC(=O)[C@H]1CNCC[C@@H]1C.O=C(O)C1(c2ccc(Cl)cc2)CCC1>>COC(=O)[C@H]1CN(C(=O)C2(c3ccc(Cl)cc3)CCC2)CC[C@@H]1C -US07560558B2,1,COc1cc2nccc(Cl)c2cc1OC.Cc1cccc(-c2nc(C)c(C)cc2O)n1>>COc1cc2nccc(Oc3cc(C)c(C)nc3-c3cccc(C)n3)c2cc1OC -US20150158846A1,6,C=CC(=O)NCCNc1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3COC(C)=O)cn(C)c2=O)n1>>C=CC(=O)NCCNc1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3CO)cn(C)c2=O)n1 -US05409943,2,Nc1ncccc1OCc1ccc(Cl)cc1.S=C=Nc1ccccc1>>S=C(Nc1ccccc1)Nc1ncccc1OCc1ccc(Cl)cc1 -US07851473B2,6,CC(C)(C)OC(=O)N1CCN(c2nc(-c3cccc(C#N)c3)cs2)CC1>>N#Cc1cccc(-c2csc(N3CCNCC3)n2)c1 -US20110053897A1,1,O=Cc1ccnc(Cl)c1.OC1CNC1>>OC1CN(Cc2ccnc(Cl)c2)C1 -US20090215759A1,1,C1CCNC1.Cc1cc(Cl)nc(Cl)n1>>Cc1cc(N2CCCC2)nc(Cl)n1 -US05409928,1,C1=COCCC1.Cc1cc(CO)ccc1Br>>Cc1cc(COC2CCCCO2)ccc1Br -US20150073011A1,6,CC(C)(C)OC(=O)NCCC1=C[C@@H](C(N)=O)N2C[C@@H]1N(OS(=O)(=O)O)C2=O>>NCCC1=C[C@@H](C(N)=O)N2C[C@@H]1N(OS(=O)(=O)O)C2=O -US20150018363A1,1,CNc1cc(Br)ccc1[N+](=O)[O-].O=c1cc(OCc2ccccc2)cc[nH]1>>CNc1cc(-n2ccc(OCc3ccccc3)cc2=O)ccc1[N+](=O)[O-] -US20080167368A1,2,CCN=C=O.NC(=O)c1c(-c2ccc([N+](=O)[O-])cc2)c[nH]c1N>>CCNC(=O)Nc1[nH]cc(-c2ccc([N+](=O)[O-])cc2)c1C(N)=O -US08778950B2,9,O=C(O)c1nn(-c2cc(Br)ccn2)c2c1C[C@@H]1C[C@H]21.[C-]#N>>N#Cc1ccnc(-n2nc(C(=O)O)c3c2[C@H]2C[C@H]2C3)c1 -US20100093757A1,6,C[C@H](CO[Si](C)(C)C(C)(C)C)OC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(F)cn1>>C[C@H](CO)OC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(F)cn1 -US20080015237A1,2,CS(=O)(=O)Cl.Cc1c(O)ccc2c1C(=O)N(Cc1ccccc1-c1ccccc1)C2C(=O)NC(C)(C)C>>Cc1c(OS(C)(=O)=O)ccc2c1C(=O)N(Cc1ccccc1-c1ccccc1)C2C(=O)NC(C)(C)C -US20130190290A1,2,CN1CCN(c2cc(C(=O)O)cc(S(F)(F)(F)(F)F)c2)CC1.Cc1ccc(N)cc1-n1ccn2nc(-c3cccnc3)cc12>>Cc1ccc(NC(=O)c2cc(N3CCN(C)CC3)cc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 -US20070043015A1,2,CC(C)(C)OC(=O)N1C(C(=O)O)COC1(C)C.C[C@@H](O[C@H]1CNC[C@@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CN(C(=O)C2COC(C)(C)N2C(=O)OC(C)(C)C)C[C@@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US04496564,2,CN.COC(=O)C1CCC(c2csc(NC(=N)N)n2)C1>>CNC(=O)C1CCC(c2csc(NC(=N)N)n2)C1 -US20130059834A1,6,CCC[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CC(F)C1>>CCC[C@@H](N)C(=O)N1CC(F)C1 -US20120157469A1,6,Cn1c2c(c3ccc(N4CCN(CCc5ccccc5)CC4=O)cc31)CCN(C(=O)OC(C)(C)C)C2>>Cn1c2c(c3ccc(N4CCN(CCc5ccccc5)CC4=O)cc31)CCNC2 -US08329687B2,1,CC(C)(C)OC(=O)N1CCOc2nc(Cl)ccc2C1.CCO>>CCOc1ccc2c(n1)OCCN(C(=O)OC(C)(C)C)C2 -US05229417,7,CN(C)CCC(=O)c1ccccc1>>CN(C)CCC(O)c1ccccc1 -US20100173939A1,2,CC1(O)CC1.NS(=O)(=O)Cl>>CC1(OS(N)(=O)=O)CC1 -US20030176454A1,1,Cc1ncc(-c2cccc(N)c2)n1C.Clc1nccc2c(Br)cccc12>>Cc1ncc(-c2cccc(Nc3nccc4c(Br)cccc34)c2)n1C -US05935990,3,Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1.O=C(Cl)c1ccccc1>>Cc1c(C(=O)c2ccccc2)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 -US04973598,2,CNCC(=O)c1ccc(F)cc1.O=C=Nc1ccccc1>>CN(CC(=O)c1ccc(F)cc1)C(=O)Nc1ccccc1 -US05478835,2,CC(C)c1ccc2c(c1)C(C(=O)O)c1ccccc1CO2.CCc1cccc(CC)c1N>>CCc1cccc(CC)c1NC(=O)C1c2ccccc2COc2ccc(C(C)C)cc21 -US20100311748A1,1,BrCc1ccccn1.COC(=O)c1ccc(O)cn1>>COC(=O)c1ccc(OCc2ccccn2)cn1 -US04096276,2,N#C[S-].Nc1c(Br)cccc1Br>>NC(=S)Nc1c(Br)cccc1Br -US07964591B2,2,O=C(Cl)c1ccccc1C(F)(F)F.O=C(NCCC1CC1)c1ccc(N2CCNCC2)nn1>>O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 -US08153652B2,1,BrCc1ccc2ccccc2c1.CN>>CNCc1ccc2ccccc2c1 -US05428053,2,Nn1cccc1.O=C(O)CNC(=O)OCc1ccccc1>>O=C(CNC(=O)OCc1ccccc1)Nn1cccc1 -US08748426B2,2,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(N)cc3)ccc2C1=O.N#Cc1ccc(N=C=S)cc1>>COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=S)Nc4ccc(C#N)cc4)cc3)ccc2C1=O -US20110257402A1,2,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CCn1ncc2c(Cl)c(NC)cnc21>>CCn1ncc2c(Cl)c(N(C)C(=O)C(C)(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cnc21 -US08071588B2,10,Cc1ccc(C#N)c(Br)c1.O=C1CCC(=O)N1Br>>N#Cc1ccc(CBr)cc1Br -US04250183,2,CCOC(=O)CNC.COc1ccc(N(CC(=O)O)C(=O)c2ccc(Cl)cc2)cc1>>CCOC(=O)CN(C)C(=O)CN(C(=O)c1ccc(Cl)cc1)c1ccc(OC)cc1 -US04512990,9,O=C(CCCCl)N1CCCc2ccccc21.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCCC(=O)N1CCCc2ccccc21 -US20090264336A1,2,C1CNC1.Cc1nc(Cl)sc1S(=O)(=O)Cl>>Cc1nc(Cl)sc1S(=O)(=O)N1CCC1 -US20080182876A1,7,Cc1cc(/C=C/C(=O)O)ccc1F>>Cc1cc(/C=C/CO)ccc1F -US20080214621A1,6,COC(=O)c1ccc(-c2ccc(C[C@@H]3CCN(C4CCCCC4)C3=O)c3ccccc23)cc1>>O=C(O)c1ccc(-c2ccc(C[C@@H]3CCN(C4CCCCC4)C3=O)c3ccccc23)cc1 -US06225310B1,2,Nc1cc(Cl)sc1S(N)(=O)=O.S=C=NC1CCCCC1>>Nc1cc(Cl)sc1S(=O)(=O)NC(=S)NC1CCCCC1 -US20110294780A1,1,CC=O.O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CCNC[C@H]1F>>CCN1CC[C@@H](N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)[C@H](F)C1 -US20100267561A1,6,COc1cnn(C)c(=O)c1-c1nn(-c2ccc(C(F)(F)F)cc2)cc1C>>Cc1cn(-c2ccc(C(F)(F)F)cc2)nc1-c1c(O)cnn(C)c1=O -US20090253672A1,6,COC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)N[C@@H](c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F>>CSCC[C@H](NC(=O)[C@H](CC(C)C)N[C@@H](c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F)C(=O)O -US20150018363A1,4,CCC(=O)O.CNc1cc(-n2ccc(OCc3ccc(F)cc3)cc2=O)ccc1N>>CCc1nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc2n1C -US05630906,8,COc1ccc(CO)cc1OC>>COc1ccc(C=O)cc1OC -US20060014945A1,7,CCOC(=O)c1ccc(OCCN2CCOCC2)c(F)c1>>OCc1ccc(OCCN2CCOCC2)c(F)c1 -US20040138462A1,2,CC(C)(C)OC(=O)N(CCc1ccc(S(=O)(=O)c2ccc(OCC(=O)[O-])cc2)cc1)C[C@H](O)c1cccc(Cl)c1.CNC>>CN(C)C(=O)COc1ccc(S(=O)(=O)c2ccc(CCN(C[C@H](O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)cc1 -US06346546B1,3,C#CCc1cccc2c1SCCC2(C)C.COC(=O)c1ccc(I)cc1O>>COC(=O)c1ccc(C#CCc2cccc3c2SCCC3(C)C)cc1O -US20120302573A1,4,Cc1nc(C)c(C(=O)CBr)s1.NC(=O)c1cccc(NC(N)=S)c1>>Cc1nc(C)c(-c2csc(Nc3cccc(C(N)=O)c3)n2)s1 -US03932496,3,C#C.CCCCC(C)(C)C(C)=O>>C#CC(C)(O)C(C)(C)CCCC -US20120277279A1,2,NCC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F.O=C(O)c1c(Cl)cccc1C(F)(F)F>>Nc1c(C(=O)NCC(O)(CNC(=O)c2c(Cl)cccc2C(F)(F)F)C(F)(F)F)cnn1-c1ccc(F)cc1 -US20100120739A1,1,Cc1ccc2nnc(Cc3ccc4ncc(-c5cn[nH]c5)cc4c3)n2n1.NC(=O)CBr>>Cc1ccc2nnc(Cc3ccc4ncc(-c5cnn(CC(N)=O)c5)cc4c3)n2n1 -US04801717,1,CC(C)I.Oc1cccc(F)c1>>CC(C)Oc1cccc(F)c1 -US08003649B2,1,C[C@H]1CN[C@H](C)CN1c1ccc2nnc(C(F)(F)F)n2n1.O=Cc1cccnc1>>C[C@H]1CN(Cc2cccnc2)[C@H](C)CN1c1ccc2nnc(C(F)(F)F)n2n1 -US20090203665A1,3,CS(=O)(=O)c1ccc(I)c(C(=O)O)c1.OB(O)c1ccc(F)c(F)c1>>CS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2)c(C(=O)O)c1 -US05527811,8,Cc1cc2c(-c3ccccc3)c(CO)n(C)c(=O)c2cc1C>>Cc1cc2c(-c3ccccc3)c(C=O)n(C)c(=O)c2cc1C -US20090198063A1,8,Cc1ncc(F)cc1CO>>Cc1ncc(F)cc1C=O -US06222048B1,3,CSc1ccc(B(O)O)cc1.O=C1OC2(CCC2)C(OS(=O)(=O)C(F)(F)F)=C1c1ccccc1>>CSc1ccc(C2=C(c3ccccc3)C(=O)OC23CCC3)cc1 -US07067527B2,6,CC(C)(C)OC(=O)COc1ccc(-c2c(Cl)c(CN3C(=O)CCC3=O)nc3sc4c(c23)CCS(=O)C4)cc1>>O=C(O)COc1ccc(-c2c(Cl)c(CN3C(=O)CCC3=O)nc3sc4c(c23)CCS(=O)C4)cc1 -US04965270,1,COc1ccc(COCCC(COCc2ccc(OC)cc2)ON)cc1.O=CNc1nc(Cl)c(NC=O)c(Cl)n1>>COc1ccc(COCCC(COCc2ccc(OC)cc2)ONc2nc(NC=O)nc(Cl)c2NC=O)cc1 -US20120028931A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1nc(C(C)C)no1)OCC>>CC(C)c1noc(C=C2CCN(C(=O)OC(C)(C)C)CC2)n1 -US20090286778A1,2,Cc1occc1N=C=O.Clc1cnc2nc1Nc1ccc(OCCC3CCNCC3)c(c1)CCc1cncc(c1)N2>>Cc1occc1NC(=O)N1CCC(CCOc2ccc3cc2CCc2cncc(c2)Nc2ncc(Cl)c(n2)N3)CC1 -US20050209284A1,1,Cc1ncc(-c2ccc(C(=O)Nc3nc4cc(C=O)ccc4n3CC(C)(C)O)s2)o1.Nc1ccccc1>>Cc1ncc(-c2ccc(C(=O)Nc3nc4cc(CNc5ccccc5)ccc4n3CC(C)(C)O)s2)o1 -US05498798,9,Cc1ccc(S(=O)(=O)Cl)cc1Cl>>Cc1ccc(S(=O)O)cc1Cl -US08173650B2,1,CC(C)(O)C1CCN(C(=O)c2nc3c(N4CCOCC4)nc(Cl)nc3s2)CC1.CCc1nc2ccccc2[nH]1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)N3CCC(C(C)(C)O)CC3)sc2n1 -US20150025087A1,1,COc1ncnc(CCl)c1C.O=[N+]([O-])c1c[nH]c2cccnc12>>COc1ncnc(Cn2cc([N+](=O)[O-])c3ncccc32)c1C -US20070249670A1,2,CC(C)(C)OC(=O)Nc1cc2ccccc2cc1C(=O)O.COC(=O)[C@](C)(N)C1CCCCC1>>COC(=O)[C@](C)(NC(=O)c1cc2ccccc2cc1NC(=O)OC(C)(C)C)C1CCCCC1 -US07361659B2,2,CC(C)(CO)NS(=O)(=O)c1cc(N)c(Cl)s1.O=C(O)c1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>CC(C)(CO)NS(=O)(=O)c1cc(NC(=O)c2cnn3c(C(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)c(Cl)s1 -US20090181965A1,4,Cc1cn(-c2ccc(NC(N)=S)cc2F)cn1.O=C1C(Br)CCCC1c1ccccc1>>Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2F)cn1 -US20040106604A1,7,COC(=O)c1cccc(-c2nn3c(c2-c2ccnc4ccccc24)CCC3)n1>>OCc1cccc(-c2nn3c(c2-c2ccnc4ccccc24)CCC3)n1 -US08378118B2,1,COc1c(C)ccc2c1CC(Br)C2=O.O=[N+]([O-])c1ccc(O)cc1>>COc1c(C)ccc2c1CC(Oc1ccc([N+](=O)[O-])cc1)C2=O -US20150057298A1,1,COC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Br)cn2)cc1.COc1ccccc1O>>COC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3OC)cn2)cc1 -US20070197551A1,6,CC(C)(C)OC(=O)N1CCc2nc(CCCCN3CCN(c4ccc5ccccc5n4)CC3)n(N)c(=O)c2C1>>Nn1c(CCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2c(c1=O)CNCC2 -US07230007B2,2,CN(C)c1cccc(-n2cc(C(=O)O)c3cccnc32)c1.N=C(N)N>>CN(C)c1cccc(-n2cc(C(=O)NC(=N)N)c3cccnc32)c1 -US07589232B2,2,CCCCc1ccc(C#Cc2ccc(CNCc3ccc(OCC(=O)OC)cc3)cc2)cc1.O=C(O)c1ccc(O)nc1>>CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(OCC(=O)OC)cc3)C(=O)c3ccc(O)nc3)cc2)cc1 -US20020026060A1,7,CCCCCC(C(=O)O)c1ccc2c(c1)C(C)(C)CCS2>>CCCCCC(CO)c1ccc2c(c1)C(C)(C)CCS2 -US07851473B2,2,CCOc1ncncc1NC(=O)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>CCOc1ncncc1NC(=O)N1CCN(c2nc(-c3ccccc3)ns2)CC1 -US06638929B2,1,COc1cc(N)c(Cl)cc1Cl.COc1cc2cc3c(Cl)c(C#N)cnc3nc2cc1OC>>COc1cc(Nc2c(C#N)cnc3nc4cc(OC)c(OC)cc4cc23)c(Cl)cc1Cl -US08088930B2,4,COc1ccc(-c2nc3cc(F)c(F)cc3n2C(COc2c(C)cc(C#N)cc2C)C2CCCCC2)c(OC)n1.[N-]=[N+]=[N-]>>COc1ccc(-c2nc3cc(F)c(F)cc3n2C(COc2c(C)cc(-c3nnn[nH]3)cc2C)C2CCCCC2)c(OC)n1 -US20060089393A1,3,Cc1ccc(C(=O)Nc2cccc(N3CCOCC3)c2)cc1B1OC(C)(C)C(C)(C)O1.Cc1nc(-c2ccc(Br)cc2)no1>>Cc1nc(-c2ccc(-c3cc(C(=O)Nc4cccc(N5CCOCC5)c4)ccc3C)cc2)no1 -US20120004269A1,3,C=CCNC(=O)C(F)(F)F.CCCC(O)(C#Cc1cccc(Br)c1)CCC>>CCCC(O)(C#Cc1cccc(/C=C/CNC(=O)C(F)(F)F)c1)CCC -US05734067,1,COc1cc(O)cc(OC)c1.O=C(O)Cc1c(F)cccc1Cl>>COc1cc(OC)cc(Oc2cccc(F)c2CC(=O)O)c1 -US07361678B2,1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccc(Cl)cc1Cl>>O=[N+]([O-])c1ccc(Oc2ccc(Cl)cc2Cl)cc1 -US20110098429A1,3,Brc1ccccn1.OB(O)c1cccc(Br)c1>>Brc1cccc(-c2ccccn2)c1 -US20030017278A1,6,CCOC(=O)c1ccc(OCc2ccccc2)cc1>>O=C(O)c1ccc(OCc2ccccc2)cc1 -US20110201602A1,1,Clc1ncccc1-c1ccncn1.Nc1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(Nc2ncccc2-c2ccncn2)ccc1F -US20100029641A1,1,CN.O=S1(=O)N(Cc2ccc(CBr)cc2)c2ccccc2N1c1ccccc1F>>CNCc1ccc(CN2c3ccccc3N(c3ccccc3F)S2(=O)=O)cc1 -US07417049B2,3,Brc1cnc2c(c1)C[C@@]1(CN3CCC1CC3)O2.OB(O)c1cc2ccccc2o1>>c1ccc2oc(-c3cnc4c(c3)C[C@@]3(CN5CCC3CC5)O4)cc2c1 -US08980889B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)c1c(I)cnn1C>>COC(=O)c1c(B2OC(C)(C)C(C)(C)O2)cnn1C -US20070244133A1,1,Nc1ccc(F)cc1.O=C(O)c1cc2c(Cl)ncnc2s1>>O=C(O)c1cc2c(Nc3ccc(F)cc3)ncnc2s1 -US20120232083A1,6,COc1cccc(-c2cc(=O)n(CC[C@](C)(C(=O)NOC3CCCCO3)S(C)(=O)=O)cc2F)c1F>>COc1cccc(-c2cc(=O)n(CC[C@](C)(C(=O)NO)S(C)(=O)=O)cc2F)c1F -US20120322788A1,4,CC(C)CC(N)=S.CCOC(=O)C(=O)CBr>>CCOC(=O)c1csc(CC(C)C)n1 -US20070155805A1,9,BrC(Br)(Br)Br.CCCCC(CCO)c1oc2cc(C)ccc2c1C>>CCCCC(CCBr)c1oc2cc(C)ccc2c1C -US20080051416A1,2,C[C@@H](O)CN.Cc1c(F)cc(C(=O)O)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O>>Cc1c(F)cc(C(=O)NC[C@@H](C)O)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O -US20130040930A1,1,CC(C)[C@@H]1CCS(=O)(=O)N1.Cc1ccc(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2)c(C)c1>>Cc1ccc(N2CCN(C(=O)c3ccc(N4[C@H](C(C)C)CCS4(=O)=O)cc3S(C)(=O)=O)CC2)c(C)c1 -US20130190347A1,2,CCN.CCOC(=O)Cn1c2c(c3cc(C)ccc31)CN(C)CC2>>CCNC(=O)Cn1c2c(c3cc(C)ccc31)CN(C)CC2 -US20130096118A1,3,C[Mg+].Cc1c(-c2cnc(C(N)=O)c3[nH]c4cc(OCC=O)ccc4c23)cccc1-n1cnc2ccccc2c1=O>>Cc1c(-c2cnc(C(N)=O)c3[nH]c4cc(OCC(C)O)ccc4c23)cccc1-n1cnc2ccccc2c1=O -US20090270363A1,9,COC(=O)c1cc(N2CCCC2)ccc1Br.N#C[Cu]>>COC(=O)c1cc(N2CCCC2)ccc1C#N -US20040142999A1,6,COC(=O)[C@H](CCc1ccccc1)OCC(=O)N1CCOCC1>>O=C(O)[C@H](CCc1ccccc1)OCC(=O)N1CCOCC1 -US04145347,2,CC(C)N(CCN)C(C)C.CCOC(=O)CN1CCCC1=O>>CC(C)N(CCNC(=O)CN1CCCC1=O)C(C)C -US20150080364A1,8,Cc1cc(CO)n(C(C)C)n1>>Cc1cc(C=O)n(C(C)C)n1 -US20080255149A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1cc(F)ccc1C(F)(F)F>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(F)ccc2C(F)(F)F)CC1 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.CCc1ccc(-c2cc(C(=O)O)no2)cc1>>CCc1ccc(-c2cc(C(=O)N3C[C@H](CC(C)C)NC(=O)[C@@H]3CC(C)C)no2)cc1 -US07354930B2,2,CCN=C=O.Nc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1>>CCNC(=O)Nc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1 -US07902252B2,6,COC(=O)c1cc2c([nH]1)C(Cc1cccc(Cl)c1)CC2>>O=C(O)c1cc2c([nH]1)C(Cc1cccc(Cl)c1)CC2 -US07365225B2,2,CC1(C)OC(=O)c2cc(NCc3ccc(C(=O)OCc4ccccc4)cc3)ccc2O1.O=C(Cl)CCC1CCCC1>>CC1(C)OC(=O)c2cc(N(Cc3ccc(C(=O)OCc4ccccc4)cc3)C(=O)CCC3CCCC3)ccc2O1 -US08163737B2,2,CO.O=C(O)c1cccc(F)c1F>>COC(=O)c1cccc(F)c1F -US20070299068A1,5,CCOc1ccc2c(C#N)c(-c3ccc(N)cc3)n(C3CCC3)c2c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOc1ccc2c(C#N)c(-c3ccc(NC(=O)C(F)(F)F)cc3)n(C3CCC3)c2c1 -US20080176830A1,1,CCOC(=O)CS.O=[N+]([O-])c1ccc(-c2ccc(C(F)(F)F)cc2)cc1CBr>>CCOC(=O)CSCc1cc(-c2ccc(C(F)(F)F)cc2)ccc1[N+](=O)[O-] -US05736534,1,COc1ccc2c(Cl)ncnc2c1.Fc1cc2c(cc1Br)NCC2>>COc1ccc2c(N3CCc4cc(F)c(Br)cc43)ncnc2c1 -US07678787B2,5,O=C(Cl)OCC1c2ccccc2-c2ccccc21.c1ccc2c(c1)Cn1cccc1CN2>>O=C(OCC1c2ccccc2-c2ccccc21)N1Cc2cccn2Cc2ccccc21 -US20130216498A1,1,Brc1nc[nH]n1.Fc1ccc2ncc(-c3nccc(N[C@@H]4CCCNC4)n3)n2c1>>Fc1ccc2ncc(-c3nccc(NC4CCCN(c5nc[nH]n5)C4)n3)n2c1 -US20130225569A1,1,Cc1c(N)ccc2[nH]ccc12.Clc1ccnc2cc(-c3ccc4c(c3)OCO4)oc12>>Cc1c(Nc2ccnc3cc(-c4ccc5c(c4)OCO5)oc23)ccc2[nH]ccc12 -US20080306115A1,6,Cc1c(C(=O)NN2CCCC(O)C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1>>Cc1c(C(=O)NN2CCCC(O)C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1 -US20060287291A1,2,CO.O=C(O)c1cccc2c1OCC2>>COC(=O)c1cccc2c1OCC2 -US07368578B2,7,COc1cc(OCc2nc(-c3ccco3)oc2C)ccc1C=O>>COc1cc(OCc2nc(-c3ccco3)oc2C)ccc1CO -US07253164B2,6,CC(C)(C)OC(=O)CN1C(=O)C(CN(C=O)OCc2ccccc2)Sc2ccccc21>>O=CN(CC1Sc2ccccc2N(CC(=O)O)C1=O)OCc1ccccc1 -US20150232465A1,1,C[C@H](N)CO.O=[N+]([O-])c1ccncc1F>>C[C@@H](CO)Nc1cnccc1[N+](=O)[O-] -US20150099719A1,1,N#CC1(NC(=O)[C@@H]2CCCC[C@H]2c2oc(-c3cccc(Cl)c3)nc2-c2ccc(Br)cc2)CC1.O=S1(=O)CCNCC1>>N#CC1(NC(=O)[C@@H]2CCCC[C@H]2c2oc(-c3cccc(Cl)c3)nc2-c2ccc(N3CCS(=O)(=O)CC3)cc2)CC1 -US20070027321A1,3,CB(O)O.CCOc1cc(Br)cnc1Nc1cccc(C)n1>>CCOc1cc(C)cnc1Nc1cccc(C)n1 -US06051712,1,BrCc1ccc2ccccc2c1.CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCCOc3ccccc3)cc2)C(O)C1>>CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCCOc3ccccc3)cc2)C(OCc2ccc3ccccc3c2)C1 -US05684030,1,Clc1ccc(CBr)cc1Cl.O=[N+]([O-])c1ccc2[nH]c(S)nc2c1>>O=[N+]([O-])c1ccc2[nH]c(SCc3ccc(Cl)c(Cl)c3)nc2c1 -US08138189B2,1,CC(c1ccc(CO)cc1Cl)C(O)(c1ccnc(Cl)c1)C(F)(F)F.COC(=O)c1cnc(Cl)nc1>>COC(=O)c1cnc(OCc2ccc(C(C)C(O)(c3ccnc(Cl)c3)C(F)(F)F)c(Cl)c2)nc1 -US20040248896A1,6,COc1cc(-c2oc(C(C)(C)C#N)cc2-c2ccncc2)ccc1Cl>>CC(C)(C#N)c1cc(-c2ccncc2)c(-c2ccc(Cl)c(O)c2)o1 -US04950733,2,CCCCCCCC(=O)Cl.OCCO>>CCCCCCCC(=O)OCCO -US03952031,4,CC(=O)C1=CC[C@H]2[C@@H]3CC[C@H]4CC=CC[C@]4(C)[C@H]3CC[C@]12C.O=C(OO)c1cccc(Cl)c1>>CC(=O)C1=CC[C@H]2[C@@H]3CC[C@H]4C[C@@H]5O[C@@H]5C[C@]4(C)[C@H]3CC[C@]12C -US20110065702A1,2,CC(C)N=C=O.Nc1ccc2c(c1)CC(=O)N2>>CC(C)NC(=O)Nc1ccc2c(c1)CC(=O)N2 -US04322353,5,O=C(CCC1SCCCS1)COCc1ccccc1.OCCO>>c1ccc(COCC2(CCC3SCCCS3)OCCO2)cc1 -US20080076774A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCOCc1cc(Br)c(C)c(Br)c1>>CCOCc1cc(Br)c(C)c(N2CCN(C(=O)OC(C)(C)C)CC2)c1 -US20020042431A1,7,CC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20120277192A1,1,C=Cc1ccnc(Cl)n1.Cc1cc(N)cc(-c2cnc(C3(O)CCC3)s2)c1>>C=Cc1ccnc(Nc2cc(C)cc(-c3cnc(C4(O)CCC4)s3)c2)n1 -US20030171351A1,2,CC(C)CCNC(=O)c1ccccc1-c1ccccc1CN.O=S(=O)(Cl)c1ccc(F)cc1>>CC(C)CCNC(=O)c1ccccc1-c1ccccc1CNS(=O)(=O)c1ccc(F)cc1 -US06469005B1,6,CCOC(=O)C(C)(O)c1ccc(Cl)cc1>>CC(O)(C(=O)O)c1ccc(Cl)cc1 -US20090233950A1,2,COc1cc2ncnc(Oc3cnc(CC(=O)O)c(OC)c3)c2cc1OC.Cc1cc(N)cc(CN(C)C)c1>>COc1cc2ncnc(Oc3cnc(CC(=O)Nc4cc(C)cc(CN(C)C)c4)c(OC)c3)c2cc1OC -US20120142685A1,1,CC(C)NC(=O)C1CCN(c2nc(-c3ccnc(Cl)c3)cc3cnccc23)CC1.NC1CCOCC1>>CC(C)NC(=O)C1CCN(c2nc(-c3ccnc(NC4CCOCC4)c3)cc3cnccc23)CC1 -US07572801B2,3,C#CCCC(=O)Nc1ncccc1C#N.Cc1cccc(I)c1>>Cc1cccc(C#CCCC(=O)Nc2ncccc2C#N)c1 -US20030225038A1,7,CCCn1c(=O)c2[nH]c(C3CC4C=CC(C3)O4)nc2n(CCC)c1=O>>CCCn1c(=O)c2[nH]c(C3CC4CCC(C3)O4)nc2n(CCC)c1=O -US04649160,7,O=C(O)COCCc1ccc(Cl)cc1>>OCCOCCc1ccc(Cl)cc1 -US04293713,2,CN(C)C(=O)N(C)C(=O)Cl.Nc1ccccc1>>CN(C)C(=O)N(C)C(=O)Nc1ccccc1 -US05292732,6,COC(CC1CCc2cc(Cl)ccc2C1=O)OC>>O=CCC1CCc2cc(Cl)ccc2C1=O -US20090023789A1,6,CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)C1(C)CCC(C(=O)OC)C1(C)C>>CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)C1(C)CCC(C(=O)O)C1(C)C -US20070238734A1,2,NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CNCC2.O=S(=O)(Cl)Nc1ccccc1>>NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CN(S(=O)(=O)Nc1ccccc1)CC2 -US04923891,8,CCCc1c(OCCCSCC2COC(C)(CCC(=O)O)S2)ccc(C(C)=O)c1O.O=C(OO)c1cccc(Cl)c1>>CCCc1c(OCCCS(=O)CC2COC(C)(CCC(=O)O)S2)ccc(C(C)=O)c1O -US07067534B1,1,C[C@@H](CCl)CBr.Oc1ccc(F)cc1>>C[C@@H](CCl)COc1ccc(F)cc1 -US20120128630A1,1,CC(C)Br.O=Cc1ccc(O)cn1>>CC(C)Oc1ccc(C=O)nc1 -US20150166480A1,2,O=C(O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2)cc1F.O[C@H]1CCCNC1>>O=C(c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2)cc1F)N1CCC[C@H](O)C1 -US20100022515A1,1,CC(C)OC(=O)N1CCC(CCOS(C)(=O)=O)CC1.O=C(OCc1ccccc1)N1CCc2cc(O)ccc2C1>>CC(C)OC(=O)N1CCC(CCOc2ccc3c(c2)CCN(C(=O)OCc2ccccc2)C3)CC1 -US20040072843A1,7,O=c1n(CCCC2CCCCC2)nnn1-c1ccc([N+](=O)[O-])cc1>>Nc1ccc(-n2nnn(CCCC3CCCCC3)c2=O)cc1 -US20120122931A1,6,COc1cc2[nH]c(-c3ccccc3)cc2cc1C>>Cc1cc2cc(-c3ccccc3)[nH]c2cc1O -US20150252038A1,6,CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC2CCN(C(c3ccc(F)c(Cl)c3)C(F)(F)F)CC2)cc1F>>O=C(O)c1cc(C2CC2)c(OCC2CCN(C(c3ccc(F)c(Cl)c3)C(F)(F)F)CC2)cc1F -US05451654,2,CC(C)(C)OOC(=O)c1ccccc1C(=O)Cl.CC(O)CO>>CC(O)COC(=O)c1ccccc1C(=O)OOC(C)(C)C -US07115749B2,9,NC(=O)c1cc(OCc2ccccc2-c2ccc(C(F)(F)F)cc2)n(CC(=O)NC2CCCCC2OCc2ccccc2)n1>>N#Cc1cc(OCc2ccccc2-c2ccc(C(F)(F)F)cc2)n(CC(=O)NC2CCCCC2OCc2ccccc2)n1 -US20140107157A1,6,Cc1c(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1>>Cc1c(C(=O)NC2CCNCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 -US20140206536A1,1,ClCc1cnc(Cl)s1.Nc1nccc2ccccc12>>Clc1ncc(CNc2nccc3ccccc23)s1 -US20100113421A1,6,CCOC(=O)c1[nH]c(C(N)=O)c(S(=O)(=O)N2CCCC2)c1C>>Cc1c(C(=O)O)[nH]c(C(N)=O)c1S(=O)(=O)N1CCCC1 -US07858781B2,7,CCOC(=O)c1coc2cc(F)ccc12>>OCc1coc2cc(F)ccc12 -US07541365B2,1,CC(C)(O)c1ccc2c(c1)C(=CCCBr)c1cccnc1CO2.OC1(c2ccccc2)CCNCC1>>CC(C)(O)c1ccc2c(c1)C(=CCCN1CCC(O)(c3ccccc3)CC1)c1cccnc1CO2 -US06333336B1,2,C1CCNC1.Cc1[nH]cc2c(=O)n(-c3ccc(Cl)cc3)nc-2c1-c1cccc(C(=O)O)c1>>Cc1[nH]cc2c(=O)n(-c3ccc(Cl)cc3)nc-2c1-c1cccc(C(=O)N2CCCC2)c1 -US20120035168A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc(N)nc(C)c1C#N>>Cc1cc(NC(=O)OC(C)(C)C)nc(C)c1C#N -US08580832B2,6,COc1cc(C=C2SC(NCC3CN(C(=O)OC(C)(C)C)CCO3)=NC2=O)ccc1Oc1ccc(C#N)cc1C(F)(F)F>>COc1cc(C=C2SC(NCC3CNCCO3)=NC2=O)ccc1Oc1ccc(C#N)cc1C(F)(F)F -US20060194844A1,1,CCOC(=O)C1CCNCC1.O=C(Nc1nc(-c2cc(Cl)cs2)c(CN2CCCCC2)s1)c1cnc(Cl)c(Cl)c1>>CCOC(=O)C1CCN(c2ncc(C(=O)Nc3nc(-c4cc(Cl)cs4)c(CN4CCCCC4)s3)cc2Cl)CC1 -US05968985,2,CC(C)(COC(=O)c1cccc(C2=CCCc3ccccc32)c1)NS(=O)(=O)C(F)(F)F.N=C(N)N>>N=C(N)NC(=O)c1cccc(C2=CCCc3ccccc32)c1 -US20120225854A1,2,O=S(=O)(Cl)c1ccsc1.OC(c1ccc(N2CCNCC2)cc1)(C(F)(F)F)C(F)(F)F>>O=S(=O)(c1ccsc1)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1 -US20120088783A1,3,Cc1c(OC2CCCCO2)cc2c(c1C)OC(C)(CCC=O)CC2.O=C1CSC(=O)N1>>Cc1c(OC2CCCCO2)cc2c(c1C)OC(C)(CCC=C1SC(=O)NC1=O)CC2 -US08278442B2,1,CC(C)C1CCC(=O)CC1.NCc1ccccc1>>CC(C)C1CCC(NCc2ccccc2)CC1 -US07582642B2,1,CC(C)n1cnc2c(NCc3cccnc3)nc(F)nc21.CC[C@H](N)C(C)(C)O>>CC[C@H](Nc1nc(NCc2cccnc2)c2ncn(C(C)C)c2n1)C(C)(C)O -US20040229858A1,1,CC(C)(C)OC(=O)N(CCO)Cc1ccccc1.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)N(CCOc1ccc(F)cc1)Cc1ccccc1 -US07598264B2,6,COc1c2c(cn(C)c1=O)CCN(Cc1ccc(F)c(Cl)c1)C2=O>>Cn1cc2c(c(O)c1=O)C(=O)N(Cc1ccc(F)c(Cl)c1)CC2 -US20150005279A1,9,CC(C)(C)OC(=O)N1CC(Oc2ccc(Br)c3[nH]ccc23)C1.[C-]#N>>CC(C)(C)OC(=O)N1CC(Oc2ccc(C#N)c3[nH]ccc23)C1 -US20030232808A1,2,CC(C)(C)OC(=O)N1CC=C(c2ccc(C(=O)O)cc2)CC1.O=S(=O)(c1ccc2cc(Cl)ccc2c1)N1CCNCC1>>CC(C)(C)OC(=O)N1CC=C(c2ccc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cc2)CC1 -US06465523B1,9,CC(Nc1c(/C=C/c2ccc(Br)cc2)c(=O)c1=O)C(C)(C)C.[C-]#N>>CC(Nc1c(/C=C/c2ccc(C#N)cc2)c(=O)c1=O)C(C)(C)C -US07649093B2,3,CCOC(=O)CP(=O)(OCC)OCC.COc1cccc(-c2c(C)cc3cc(OC)ccc3c2Oc2ccc(C=O)cc2)c1>>CCOC(=O)/C=C/c1ccc(Oc2c(-c3cccc(OC)c3)c(C)cc3cc(OC)ccc23)cc1 -US20100331335A1,7,O=[N+]([O-])c1ccc(Br)c2ccncc12>>Nc1ccc(Br)c2ccncc12 -US20110105474A1,6,CCOC(=O)/C=C/c1ccc(/C=C/C(=O)NOC2CCCCO2)cc1>>O=C(O)/C=C/c1ccc(/C=C/C(=O)NOC2CCCCO2)cc1 -US20110178053A1,1,C1COCCN1.Clc1cnc2[nH]c3cnc(-c4cccnc4)cc3c2c1>>c1cncc(-c2cc3c(cn2)[nH]c2ncc(N4CCOCC4)cc23)c1 -US20050148624A1,1,COC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2c(=O)n1N.O=Cc1ccoc1>>COC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2c(=O)n1N=Cc1ccoc1 -US07833694B2,1,C=C(C)C(=O)[O-].COC(=O)C1C2CC3C(OC(=O)C31)C2OC(=O)CCCCl>>C=C(C)C(=O)OCCCC(=O)OC1C2CC3C1OC(=O)C3C2C(=O)OC -US07304062B2,6,CCCn1c(CCc2ccc(OC(C)(C)C(=O)OCC)cc2)nn(-c2ccc(C(F)(F)F)cc2)c1=O>>CCCn1c(CCc2ccc(OC(C)(C)C(=O)O)cc2)nn(-c2ccc(C(F)(F)F)cc2)c1=O -US20150111870A1,8,COc1nc2ccc(C(O)c3cnc(C)n3C)cc2c(Cl)c1CC(C)C>>COc1nc2ccc(C(=O)c3cnc(C)n3C)cc2c(Cl)c1CC(C)C -US07294635B2,7,CN(C(=O)OC(C)(C)C)c1cc2ccn(-c3ccc([N+](=O)[O-])cc3)c(=O)c2cc1F>>CN(C(=O)OC(C)(C)C)c1cc2ccn(-c3ccc(N)cc3)c(=O)c2cc1F -US20090318501A1,3,CON(C)C(=O)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1.Fc1cc(Cl)cc(Br)c1>>CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)c2cc(F)cc(Cl)c2)C1 -US08314126B2,1,CI.O=S(=O)(c1cccc(C2CCNCC2)c1F)C(F)(F)F>>CN1CCC(c2cccc(S(=O)(=O)C(F)(F)F)c2F)CC1 -US06242449B1,1,CCOC(=O)CCCn1cc(C(=O)c2ccc(N)c(OCCCN3CCN(c4ccccc4OC)CC3)c2)c2ccccc21.ClC(c1ccccc1)c1ccccc1>>CCOC(=O)CCCn1cc(C(=O)c2ccc(NC(c3ccccc3)c3ccccc3)c(OCCCN3CCN(c4ccccc4OC)CC3)c2)c2ccccc21 -US20050070583A1,6,COC(=O)COc1ccc(SCC=C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1C>>Cc1cc(SCC=C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)ccc1OCC(=O)O -US05527780,7,NCCC=Cc1ccc(-c2ccccc2)cc1>>NCCCCc1ccc(-c2ccccc2)cc1 -US06528068B1,2,CC(C)O.CCCCCCCCCCCC(=O)N(C)CCC(=O)O>>CCCCCCCCCCCC(=O)N(C)CCC(=O)OC(C)C -US07579488B2,7,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc2oc(C(=O)O)c(C)c2c1>>CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1ccc2oc(C(=O)O)c(C)c2c1 -US20120220776A1,1,COc1cc(C=O)ccc1O.ClCCCBr>>COc1cc(C=O)ccc1OCCCCl -US20050137214A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc4ccc(=O)n(C5CC5)c4n3)nc2)CC1>>O=c1ccc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CC1 -US20080280906A1,1,O=C(c1ccc(I)cc1)N1CCCNCC1.O=C1CCC1>>O=C(c1ccc(I)cc1)N1CCCN(C2CCC2)CC1 -US06916850B2,1,CCOC(=O)C(=O)CBr.Sc1nc2ccccc2[nH]1>>CCOC(=O)C(=O)CSc1nc2ccccc2[nH]1 -US20150057273A1,2,CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2N)cc1Cl)(C(C)C)C(C)C.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1Cl)(C(C)C)C(C)C -US08765940B2,1,C1COCCN1.Cc1ncccc1-c1nc2cc(F)ccc2c(N2CC(C)(C)c3ncc(Br)cc32)c1C>>Cc1ncccc1-c1nc2cc(F)ccc2c(N2CC(C)(C)c3ncc(N4CCOCC4)cc32)c1C -US08546588B2,6,CCOC(=O)c1cc([C@@H](C)NC(=O)c2cc3ccccc3o2)no1>>C[C@@H](NC(=O)c1cc2ccccc2o1)c1cc(C(=O)O)on1 -US20040132772A1,6,COc1ccc(N(C(C)=O)[C@@H]2C[C@H](C)N(C(=O)c3ccccc3)c3ccccc32)cc1>>CC(=O)N(c1ccc(O)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccccc2)c2ccccc21 -US06545161B2,2,Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)cc2N)c1=O.O=C(Cl)c1ccc2ccccc2c1>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)cc2NC(=O)c2ccc3ccccc3c2)c1=O -US20020103247A1,1,CC(C)(C)OC(=O)n1ccc2cc(OCCCCBr)ccc21.CCNCC>>CCN(CC)CCCCOc1ccc2c(ccn2C(=O)OC(C)(C)C)c1 -US07683185B2,6,COC(=O)CCCCCSc1ccc(N(C)C)cc1>>CN(C)c1ccc(SCCCCCC(=O)O)cc1 -US20110060146A1,3,CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1.COC(=O)C(O)c1ccc(Br)cc1>>CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(C(O)C(=O)OC)cc2)c(C)c1 -US05175356,1,C1CNCCN1.C=Cc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>C=Cc1c(N2CCNCC2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US20100130490A1,1,Clc1cncc(Cl)n1.c1nc[nH]n1>>Clc1cncc(-n2cncn2)n1 -US20090281292A1,7,COc1ccc(C(=O)CN)cc1>>COc1ccc(C(O)CN)cc1 -US08969587B2,1,CC(C)(C)c1cc(NC(=O)Nc2cccc(O)c2)no1.Clc1ncnc2cc(OCc3ccccc3)ccc12>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3ncnc4cc(OCc5ccccc5)ccc34)c2)no1 -US07271274B2,1,CC(C)(Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.CCOC1O[C@@H](CO)[C@H](CO)O1>>CCOC1O[C@@H](CO)[C@H](COc2c(C(C)(C)C)cc(SC(C)(C)Sc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)cc2C(C)(C)C)O1 -US08394799B2,2,COC(=O)c1ccc(N)cc1.O=C(O)COc1ccc(Cl)cc1Cl>>COC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 -US20100105732A1,1,CC(C)c1noc(N2CCC(CCCO)CC2)n1.Cc1cc(Cl)ncc1Br>>Cc1cc(OCCCC2CCN(c3nc(C(C)C)no3)CC2)ncc1Br -US05723479,6,COC(=O)c1cc2ccc(OC)cc2o1>>COC(=O)c1cc2ccc(O)cc2o1 -US20130131083A1,9,NO.O=Cc1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(C=NO)ccc1F -US20150210675A1,1,C=CCCCCBr.OCC1CCCCC1>>C=CCCCCOCC1CCCCC1 -US05066658,1,CCCCCCCCCCNO.CCN(CC)C(=O)Cl>>CCCCCCCCCCN(O)C(=O)N(CC)CC -US06248739B1,1,CNCCO.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CO)ccc21>>CN(CCO)Cc1ccc2c(c1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C -US20040063975A1,1,COC(=O)CBr.Cc1c(OC2CCCCO2)cc(C=O)c(O)c1C>>COC(=O)COc1c(C=O)cc(OC2CCCCO2)c(C)c1C -US06511974B1,1,FC(F)(F)c1cc[nH]n1.O=C(c1ccc(F)cc1Cl)N1Cc2cccn2Cc2ccccc21>>O=C(c1ccc(-n2ccc(C(F)(F)F)n2)cc1Cl)N1Cc2cccn2Cc2ccccc21 -US20090192192A1,1,C=CC(=O)OC(C)(C)C.CCCCCCCCO>>CCCCCCCCOCCC(=O)OC(C)(C)C -US20020019414A1,7,COC(=O)c1cc2c(cc1[N+](=O)[O-])OCO2>>COC(=O)c1cc2c(cc1N)OCO2 -US20120077794A1,1,CC(C)(C)OC(=O)NCCN1CCNCC1.O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(F)nc1>>CC(C)(C)OC(=O)NCCN1CCN(c2ccc(-n3ccc(OCc4ccc(Cl)cn4)cc3=O)cn2)CC1 -US07563793B2,2,CC1Nc2cc(Br)ccc2-n2cccc21.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)N2c3cc(Br)ccc3-n3cccc3C2C)cc1 -US20150182507A1,6,COC(=O)c1cccc(NC(=O)NCc2nc3ccccn3c2C#Cc2cccc(C(F)(F)F)c2)c1>>O=C(NCc1nc2ccccn2c1C#Cc1cccc(C(F)(F)F)c1)Nc1cccc(C(=O)O)c1 -US06084130,1,CCCCBr.CCCN(CCC)C1Cc2cc(O)c(OS(=O)(=O)C(F)(F)F)cc2C1>>CCCCOc1cc2c(cc1OS(=O)(=O)C(F)(F)F)CC(N(CCC)CCC)C2 -US08664220B2,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.CCc1noc(-c2ccc(Br)cc2)c1Nc1nnc(-c2ccccc2)o1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(CC)c4Nc4nnc(-c5ccccc5)o4)cc3)cc2)CC1 -US20040110745A1,1,C1COCCN1.N#Cc1cc([N+](=O)[O-])ccc1F>>N#Cc1cc([N+](=O)[O-])ccc1N1CCOCC1 -US20100041721A1,2,Cc1c(N[C@@H](C(=O)O)[C@@H](C)O)ccc(C#N)c1Cl.NNC(=O)c1cccc(O)c1>>Cc1c(N[C@@H](C(=O)NNC(=O)c2cccc(O)c2)[C@@H](C)O)ccc(C#N)c1Cl -US07999132B2,3,C=Cc1cccc(OC)c1.CC(C)(C)OC(=O)c1ccc(Br)cc1[N+](=O)[O-]>>COc1cccc(/C=C/c2ccc(C(=O)OC(C)(C)C)c([N+](=O)[O-])c2)c1 -US20020068827A1,2,CC(O)C(N)c1ccccc1.Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)Cl>>Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)NC(c1ccccc1)C(C)O -US05859014,6,CC(C)(COCc1ccccc1)CN1CCN(c2ccccc2OCC(F)(F)F)CC1>>CC(C)(CO)CN1CCN(c2ccccc2OCC(F)(F)F)CC1 -US20070021473A1,1,CCOC(=O)c1ccc(-c2ccc(OCCCI)c(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c2)cc1.NC1CC1>>CCOC(=O)c1ccc(-c2ccc(OCCCNC3CC3)c(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c2)cc1 -US20030083359A1,1,N#Cc1cccc(C=O)c1.N[C@H]1CCCc2ccccc21>>N#Cc1cccc(CN[C@H]2CCCc3ccccc32)c1 -US07282496B2,6,C=C=CCOc1ccc(S(=O)(=O)N2CCSC(C)(C)[C@@H]2C(=O)OC)cc1>>C=C=CCOc1ccc(S(=O)(=O)N2CCSC(C)(C)C2C(=O)O)cc1 -US08143274B2,2,Nc1ccc2cc(-c3ccccc3)[nH]c(=O)c2c1.O=C(Cl)CCl>>O=C(CCl)Nc1ccc2cc(-c3ccccc3)[nH]c(=O)c2c1 -US20140249133A1,1,N#Cc1cnc(-c2nn(Cc3ccccc3F)c3ccccc23)nc1Cl.Nc1ccncc1>>N#Cc1cnc(-c2nn(Cc3ccccc3F)c3ccccc23)nc1Nc1ccncc1 -US20100298336A1,1,C=Cc1ncsc1CBr.Oc1cc(C(F)(F)F)nc(S)n1>>C=Cc1ncsc1CSc1nc(O)cc(C(F)(F)F)n1 -US20090275570A1,9,O=c1[nH]c(Br)c(Br)c2oc(-c3ccccc3)cc12>>O=c1[nH]cc(Br)c2oc(-c3ccccc3)cc12 -US20050277630A1,7,CCCC(=O)OCC1CN(c2ccc3c(c2)CCC(NC(=O)OCc2ccccc2)C(=O)N3)C(=O)O1>>O=C(N[C@@H]1CCc2cc(N3CC(CO)OC3=O)ccc2NC1=O)OCc1ccccc1 -US20150057264A1,9,O=c1[nH]c(-c2ccc(Br)cc2)cn2nc(CBr)cc12>>Cc1cc2c(=O)[nH]c(-c3ccc(Br)cc3)cn2n1 -US20130029938A1,6,CCCC[C@]1(CC)CS(=O)(=O)c2cc(C(=O)OC)c(OC)cc2[C@@H](c2ccccc2)N1>>CCCC[C@]1(CC)CS(=O)(=O)c2cc(C(=O)O)c(OC)cc2[C@@H](c2ccccc2)N1 -US06521643B1,7,COc1cccnc1-c1cccc([N+](=O)[O-])c1>>COc1cccnc1-c1cccc(N)c1 -US20100004249A1,6,CC(C)(C)OC(=O)N1CCN2C(=O)N(c3cccnc3)CC2C1>>O=C1N(c2cccnc2)CC2CNCCN12 -US20120142633A1,2,CC(C)(C)OC(=O)N1CCC(N)CC1.COc1ccc(-c2ccnc3c(C(=O)O)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)c1>>COc1ccc(-c2ccnc3c(C(=O)NC4CCN(C(=O)OC(C)(C)C)CC4)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)c1 -US20100216746A1,1,Cc1ccc(Cl)c(O)c1F.N#Cc1cc(F)cc(C(F)(F)F)c1>>Cc1ccc(Cl)c(Oc2cc(C#N)cc(C(F)(F)F)c2)c1F -US20080280950A1,2,C[C@]1(CS(=O)(=O)Cl)NC(=O)NC1=O.FC(F)(F)C(F)(F)COc1ccc(OC2CCNCC2)cc1>>C[C@]1(CS(=O)(=O)N2CCC(Oc3ccc(OCC(F)(F)C(F)(F)F)cc3)CC2)NC(=O)NC1=O -US20150284580A1,6,COc1cccc(OC)c1OC>>COc1cccc(OC)c1O -US04280957,7,Cc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1F)=NC2>>Cc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1F)NC2 -US20110212940A1,3,Cc1nc(Cl)ccc1C=O.OB(O)c1cc2cc(Cc3ccccc3)ccc2o1>>Cc1nc(-c2cc3cc(Cc4ccccc4)ccc3o2)ccc1C=O -US20050261269A1,1,C1=C(c2ccccc2)CCNC1.O=[N+]([O-])c1ccc(CCO)cc1>>O=[N+]([O-])c1ccc(CCN2CC=C(c3ccccc3)CC2)cc1 -US06541466B2,2,CCC(N)C(=O)OCC(C)C.O=C(O)Cc1ccccc1O>>CCC(NC(=O)Cc1ccccc1O)C(=O)OCC(C)C -US20090270365A1,7,CN1C(=O)C(F)(F)c2cc([N+](=O)[O-])ccc21>>CN1C(=O)C(F)(F)c2cc(N)ccc21 -US20110046108A1,1,COc1ccc(Cn2nc(C)c3c(N)cccc32)cc1.CSc1nccc(Cl)n1>>COc1ccc(Cn2nc(C)c3c(Nc4ccnc(SC)n4)cccc32)cc1 -US20110152326A1,1,Cc1cccnc1C(=O)CBr.O=C[N-]C=O>>Cc1cccnc1C(=O)CN(C=O)C=O -US07189851B2,2,CCOC(=O)c1c(CCc2ccc(C(F)(F)F)cc2)nc2c(c1-c1ccc(C(=O)O)cc1)C(=O)N1CCC[C@@H]21.C[C@@H](N)c1ccncc1>>CCOC(=O)c1c(CCc2ccc(C(F)(F)F)cc2)nc2c(c1-c1ccc(C(=O)N[C@H](C)c3ccncc3)cc1)C(=O)N1CCC[C@@H]21 -US20070049632A1,1,Cn1[nH]c(=O)c2c1[C@@]1(C)CC[C@@H]2C1(C)C.FC(F)(F)c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1CBr>>Cn1c2c(c(=O)n1Cc1cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)nc1C(F)(F)F)[C@@H]1CC[C@@]2(C)C1(C)C -US08034812B2,2,COc1cc(C(=O)O)n(C)n1.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F>>COc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2F)n(C)n1 -US20140243286A1,2,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCN)c1nnc(C)n1-2.O=C(O)c1ccc(B(O)O)cc1>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCNC(=O)c1ccc(B(O)O)cc1)c1nnc(C)n1-2 -US05292887,7,CCOC(=O)C1(c2c[nH]cn2)Cc2ccccc2C1>>OCC1(c2c[nH]cn2)Cc2ccccc2C1 -US05190975,2,COC(=O)Cc1ccc2c(c1)CC(N)C2.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)Cc1ccc2c(c1)CC(NS(=O)(=O)c1ccc(Cl)cc1)C2 -US07534801B2,7,O=C1CCOc2ccc([N+](=O)[O-])cc21>>Nc1ccc2c(c1)C(=O)CCO2 -US04814338,1,CC#Cc1cc(Cl)nc(Nc2ccccc2)n1.CNC>>CC#Cc1cc(N(C)C)nc(Nc2ccccc2)n1 -US20100036118A1,6,COC(=O)c1cc(I)cc(C(=O)OC)c1>>COC(=O)c1cc(I)cc(C(=O)O)c1 -US05665718,9,CN1Cc2c(C(=O)O)ncn2-c2cccc(Br)c2C1=O.N>>CN1Cc2c(C(N)=O)ncn2-c2cccc(Br)c2C1=O -US20150158872A1,1,CC(C)(C)OC(=O)C1CCNCC1.Fc1cncc(Br)c1Cl>>CC(C)(C)OC(=O)C1CCN(c2c(F)cncc2Br)CC1 -US20070197551A1,1,CC(C)(C)OC(=O)N1CCN(c2nccc3ccc(O)cc23)CC1.CCI>>CCOc1ccc2ccnc(N3CCN(C(=O)OC(C)(C)C)CC3)c2c1 -US06586441B2,1,Cc1ccc(CN)cc1C.N#Cc1c(OS(=O)(=O)C(F)(F)F)nc(N)nc1C1=CCCO1>>Cc1ccc(CNc2nc(N)nc(C3=CCCO3)c2C#N)cc1C -US20120039804A1,1,BrCc1cccnc1.O=C(c1ccc2[nH]c3ccccc3c2c1)N1CCCCC1>>O=C(c1ccc2c(c1)c1ccccc1n2Cc1cccnc1)N1CCCCC1 -US07268128B2,6,CCOC(=O)C1CCN(S(=O)(=O)c2ccc(-c3nc4c(c(C5CCCCC5)nn4C)c(=O)[nH]3)c(OC)c2)CC1>>COc1cc(S(=O)(=O)N2CCC(C(=O)O)CC2)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1 -US05506267,6,CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)OCc1ccc(OC)cc1)OC(=O)CCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)O)OC(=O)CCCCCCCCCCCCCCC -US20150197726A1,2,NCc1ccccc1.O=C(O)c1cccc2nc(-c3c(NCCc4cccc(Cl)c4)cc[nH]c3=O)[nH]c12>>O=C(NCc1ccccc1)c1cccc2nc(-c3c(NCCc4cccc(Cl)c4)cc[nH]c3=O)[nH]c12 -US20050197342A1,3,Clc1cc(Cl)ncn1.OB(O)c1cccc2ncccc12>>Clc1cc(-c2cccc3ncccc23)ncn1 -US09096634B2,2,CN(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C1CC(CCC(=O)O)C1.Nc1ccc(C2COC2)cc1N>>CN(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C1CC(CCC(=O)Nc2cc(C3COC3)ccc2N)C1 -US06703392B2,1,CCI.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NC1CCc3ccccc31)CC2>>CCOc1cc2c(cc1OC)CCN(CC(=O)NC1CCc3ccccc31)C2Cc1ccc(OC)c(OC)c1 -US20150152047A1,2,CCS(=O)(=O)Cl.N#Cc1ccc[nH]1>>CCS(=O)(=O)n1cccc1C#N -US20040229870A1,1,Cc1cc(Cl)c([N+](=O)[O-])c(O)n1.NCc1ccccc1>>Cc1cc(NCc2ccccc2)c([N+](=O)[O-])c(O)n1 -US20130225673A1,6,CCc1oc2ccccc2c1C(=O)c1ccc(OC)c(Br)c1>>CCc1oc2ccccc2c1C(=O)c1ccc(O)c(Br)c1 -US05856556,2,CC(=NC(=O)OCc1ccc([N+](=O)[O-])cc1)N1CC[C@H](SC(=O)C[C@@H]2[C@@H]([C@@H](C)O)C(=O)N2C(C(=O)OCc2ccc([N+](=O)[O-])cc2)=C(C)C)C1.O=C(Cl)OCc1ccc([N+](=O)[O-])cc1>>CC(=NC(=O)OCc1ccc([N+](=O)[O-])cc1)N1CC[C@H](SC(=O)C[C@@H]2[C@@H]([C@@H](C)OC(=O)OCc3ccc([N+](=O)[O-])cc3)C(=O)N2C(C(=O)OCc2ccc([N+](=O)[O-])cc2)=C(C)C)C1 -US20140350019A1,7,Cc1cc(-c2ccc(F)c(F)c2)cc(C(=O)Nc2c(F)ccc(O)c2F)c1C>>Cc1cc(-c2ccc(F)c(F)c2)cc(CNc2c(F)ccc(O)c2F)c1C -US20060257987A1,3,CCc1ccc(O)c(Br)c1.OB(O)c1cccnc1>>CCc1ccc(O)c(-c2cccnc2)c1 -US20140154179A1,6,Cc1cn2cccc2c(N2CCC(NC(=O)OC(C)(C)C)C2)n1>>Cc1cn2cccc2c(N2CCC(N)C2)n1 -US06608218B2,6,COC(=O)C(OC1C=CCCC1)c1ccc(S(C)(=O)=O)c(Cl)c1>>CS(=O)(=O)c1ccc(C(OC2C=CCCC2)C(=O)O)cc1Cl -US05134128,7,CCOC(=O)CCCCCCCCc1ccccc1>>OCCCCCCCCCc1ccccc1 -US07196087B2,1,CC(C)(C)OC(=O)N1CCNCC1.CN1Cc2c(Br)cccc2N(Cc2cccc(F)c2)C1=O>>CN1Cc2c(N3CCN(C(=O)OC(C)(C)C)CC3)cccc2N(Cc2cccc(F)c2)C1=O -US20120165346A1,3,Cc1cc(C2(c3cccc(Br)c3)N=C(N)c3c(F)cccc32)cn(C)c1=O.OB(O)c1cncc(Cl)c1>>Cc1cc(C2(c3cccc(-c4cncc(Cl)c4)c3)N=C(N)c3c(F)cccc32)cn(C)c1=O -US20080032998A1,2,CC1CC(c2ccccc2Cl)=CCN1.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1CC(c2ccccc2Cl)=CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US07915427B2,2,N#C[C@@H]1C[C@H](F)CN1C(=O)CO.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>N#C[C@@H]1C[C@H](F)CN1C(=O)COS(=O)(=O)c1ccccc1[N+](=O)[O-] -US20100029720A1,2,N#CC(CCC(=O)O)(c1ccccc1)c1ccccc1.c1ccc(OC2CCNCC2)cc1>>N#CC(CCC(=O)N1CCC(Oc2ccccc2)CC1)(c1ccccc1)c1ccccc1 -US08835457B2,1,Cc1ccc(C=O)cc1NS(C)(=O)=O.c1cc2[nH]ncc2cc1NC12CCC(C1)NC2>>Cc1ccc(CN2CC3(Nc4ccc5[nH]ncc5c4)CCC2C3)cc1NS(C)(=O)=O -US20100009969A1,8,Cc1ccc(S(=O)(=O)N2CC(O)C(Br)C2)cc1>>Cc1ccc(S(=O)(=O)N2CC(=O)C(Br)C2)cc1 -US20050148627A1,6,CCOC(=O)C1=Cc2c(F)cccc2OC1C(F)(F)F>>O=C(O)C1=Cc2c(F)cccc2OC1C(F)(F)F -US20140128392A1,6,COC(=O)/C=C/c1ccc2nc(-c3ccc(OC)cc3)c(-c3ccc(OC)cc3)nc2c1>>COc1ccc(-c2nc3ccc(/C=C/C(=O)O)cc3nc2-c2ccc(OC)cc2)cc1 -US08067408B2,2,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)O)c1.NCc1cccc(Br)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)NCc2cccc(Br)c2)c1 -US20060004084A1,2,Nc1ccc2c(c1)COC2=C1C(=O)Nc2ccc(Cl)cc21.O=C(CBr)OC(=O)CBr>>O=C(CBr)Nc1ccc2c(c1)COC2=C1C(=O)Nc2ccc(Cl)cc21 -US04499299,10,COC(=O)C=Cc1ccc(C)cc1.O=C1CCC(=O)N1Br>>COC(=O)C=Cc1ccc(CBr)cc1 -US06458778B1,7,C[C@]12CC[C@H]3C(=CCC4=C3CCC(=O)C4)[C@@H]1CC1OCCOC12>>C[C@]12CC[C@H]3C(=CCC4=C3CCC(O)C4)[C@@H]1CC1OCCOC12 -US08163793B2,1,Cc1cc(N2C[C@H](S(=O)(=O)c3ccc(F)cc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)n(CCc2ccccc2)n1.OCC(F)(F)F>>Cc1cc(N2C[C@H](S(=O)(=O)c3ccc(OCC(F)(F)F)cc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)n(CCc2ccccc2)n1 -US06979693B2,6,COc1cccc(C(=O)c2cnn(-c3ccc(F)cc3)c2N)c1>>Nc1c(C(=O)c2cccc(O)c2)cnn1-c1ccc(F)cc1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](c2ccccc2)NC1=O.O=C(O)[C@@H]1C[C@H]1c1ccc(Cl)cc1F>>CC(C)C[C@H]1C(=O)N[C@@H](c2ccccc2)CN1C(=O)[C@@H]1C[C@H]1c1ccc(Cl)cc1F -US20130217666A1,3,C#CC1(O)CCC1.CNC(=O)c1c(C(N)=O)nc2n1CCOc1ccc(Br)cc1-2>>CNC(=O)c1c(C(N)=O)nc2n1CCOc1ccc(C#CC3(O)CCC3)cc1-2 -US06593326B1,1,CN(C)CC(O)COc1ccc(N)cc1.Clc1ncc(Br)c(Nc2ccc3c(c2)CCC3)n1>>CN(C)CC(O)COc1ccc(Nc2ncc(Br)c(Nc3ccc4c(c3)CCC4)n2)cc1 -US08916557B2,1,CS(=O)(=O)Cc1cccc(Nc2ncnc(-c3ccc(F)cc3F)n2)c1.OCc1ccc(F)c(F)c1F>>CS(=O)(=O)Cc1cccc(Nc2ncnc(-c3ccc(F)cc3OCc3ccc(F)c(F)c3F)n2)c1 -US08252935B2,1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C(F)(F)F)N2)c1.COc1ccc(CBr)cc1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C(F)(F)F)N2Cc2ccc(OC)cc2)c1 -US20130210801A1,1,CCI.Cc1ccc2c(Br)c([C@H](OC(C)(C)C)C(=O)O)c(C)cc2n1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(C)ccc2c1Br -US05086056,6,CCOCCn1c(CN2CCN(Cc3ccccc3)CC2)nc2ncccc21>>CCOCCn1c(CN2CCNCC2)nc2ncccc21 -US20140121198A1,2,CC(C)OC(=O)Cl.C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@@H]1CC[C@@H](CN)CC1>>CC(C)OC(=O)NC[C@@H]1CC[C@@H](n2c([C@@H](C)O)nc3cnc4ccsc4c32)CC1 -US20130059834A1,2,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](CO)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](COS(C)(=O)=O)C1 -US20060058304A1,1,Cc1noc(-c2cn3ncnc(Cl)c3c2C(C)C)n1.Nc1cnc2[nH]ccc2c1F>>Cc1noc(-c2cn3ncnc(Nc4cnc5[nH]ccc5c4F)c3c2C(C)C)n1 -US07141352B2,1,CC(=O)OCCCBr.c1ccc2[nH]cnc2c1>>CC(=O)OCCCn1cnc2ccccc21 -US04337267,6,CCOC(=O)C1(CCCCCOc2ccc(Cl)cc2)CO1>>O=C(O)C1(CCCCCOc2ccc(Cl)cc2)CO1 -US20060270848A1,1,C1CNCCN1.CC(C)(C)c1ccc(-c2cn3cccc(Br)c3n2)cc1>>CC(C)(C)c1ccc(-c2cn3cccc(N4CCNCC4)c3n2)cc1 -US05736548,2,CCc1[nH]n(C2CCCC2)c2nc(-c3ccc(N)cc3)nc(=O)c1-2.CS(=O)(=O)Cl>>CCc1[nH]n(C2CCCC2)c2nc(-c3ccc(NS(C)(=O)=O)cc3)nc(=O)c1-2 -US08431695B2,1,CI.Nc1ncnn2c(C3CN4CCNCC4CO3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>CN1CCN2CC(c3cc(-c4ccc5cn(Cc6ccccc6)nc5c4)c4c(N)ncnn34)OCC2C1 -US04777178,1,ClCCCBr.OCc1ccccc1S>>OCc1ccccc1SCCCCl -US20110306590A1,6,CC(C)(C)OC(=O)N1CC(c2ccc3ccccc3n2)C1>>c1ccc2nc(C3CNC3)ccc2c1 -US08232391B2,6,COc1ccc2nccc(-n3cc4c(n3)CCC(N(CCOc3ccccc3)C(=O)OC(C)(C)C)C4)c2n1>>COc1ccc2nccc(-n3cc4c(n3)CCC(NCCOc3ccccc3)C4)c2n1 -US08735387B2,7,C=C(c1ccccc1)c1nc(OCCC)c2nc(-c3cccc(C)c3)oc2n1>>CCCOc1nc(C(C)c2ccccc2)nc2oc(-c3cccc(C)c3)nc12 -US05665733,7,COC(=O)/C=C/c1c(-c2ccccc2)n(C)c(=O)c2ccccc12>>COC(=O)CCc1c(-c2ccccc2)n(C)c(=O)c2ccccc12 -US05162334,6,C=CCOC1CC(C=C(C)C2OC(=O)C3CCCCN3C(=O)C(=O)C3(O)OC(C(OC)CC(C)CC(C)=CC(CC)C(=O)CC(O[Si](C)(C)C(C)(C)C)C2C)C(OC)CC3C)CCC1O[Si](C)(C)C(C)(C)C>>C=CCOC1CC(C=C(C)C2OC(=O)C3CCCCN3C(=O)C(=O)C3(O)OC(C(OC)CC(C)CC(C)=CC(CC)C(=O)CC(O[Si](C)(C)C(C)(C)C)C2C)C(OC)CC3C)CCC1O -US20150183801A1,1,CNCCO.O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1>>CN(CCO)c1ncc(C(=O)Nc2ccc(SC(F)(F)F)cc2)cc1Br -US04433152,6,N=C(N)N1CCC(CCC(=O)Oc2ccccc2C(=O)OCc2ccccc2)CC1>>N=C(N)N1CCC(CCC(=O)Oc2ccccc2C(=O)O)CC1 -US20050014767A1,3,CCC(C)(C)c1cc(-c2ccc(C=O)cn2)ccc1O.O=C1CSC(=O)N1>>CCC(C)(C)c1cc(-c2ccc(C=C3SC(=O)NC3=O)cn2)ccc1O -US20110008727A1,3,CC[Mg+].O=C1CCCCCCC1>>CCC1(O)CCCCCCC1 -US20100016399A1,6,CCOC(=O)CN1C(=O)C(c2ccc(OC)cc2)CC12CCCCC2>>COc1ccc(C2CC3(CCCCC3)N(CC(=O)O)C2=O)cc1 -US08853218B2,1,C[C@H]1CNC[C@@H](C)N1.O=Cc1ccc([N+](=O)[O-])cc1>>C[C@H]1CN(Cc2ccc([N+](=O)[O-])cc2)C[C@@H](C)N1 -US20120071459A1,9,ICI.Nc1ccc(-n2ccc(OCc3ccc(Cl)cn3)cc2=O)cn1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(I)nc1 -US04618627,3,BrC1CCCCC1.O=CCCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>OC(CCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)C1CCCCC1 -US04898874,10,Cc1ccc2noc(-c3ccccc3)c2c1.O=C1CCC(=O)N1Br>>BrCc1ccc2noc(-c3ccccc3)c2c1 -US20040053942A1,2,Cc1ccccc1C(=O)O.OCc1ccn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2c1>>Cc1ccccc1C(=O)OCc1ccn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2c1 -US20060167059A1,3,Brc1cccc2ccn(Cc3ccccc3)c12.OB(O)c1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(-c2cccc3ccn(Cc4ccccc4)c23)cc1 -US20150252038A1,1,COc1ccc(CCl)cc1.O=C1CO[C@H](Cc2cc(Cl)cc(Cl)c2)CN1>>COc1ccc(CN2C[C@@H](Cc3cc(Cl)cc(Cl)c3)OCC2=O)cc1 -US20130065914A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](O)C1.O=[N+]([O-])c1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cc(F)ccc2[N+](=O)[O-])C1 -US20120094964A1,2,CS(=O)(=O)Cl.NCc1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1>>CS(=O)(=O)NCc1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1 -US07807684B2,10,Cc1nc2cccc(Cl)c2s1.O=C1CCC(=O)N1Br>>Clc1cccc2nc(CBr)sc12 -US20120289522A1,3,CCOC(=O)CC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1CSCCc1ccccc1>>CCOC(=O)CC1(c2ccc(-c3ccc(-c4onc(C)c4CSCCc4ccccc4)cc3)cc2)CC1 -US05637710,1,CN(C)CCCCl.Fc1ccc2c(C3CCNCC3)noc2c1>>CN(C)CCCN1CCC(c2noc3cc(F)ccc23)CC1 -US07750161B2,1,CCN(C1CCNCC1)S(=O)(=O)c1ccc(OC)cc1.Cc1cc(NC(=O)NCCCl)cc(C)n1>>CCN(C1CCN(CCNC(=O)Nc2cc(C)nc(C)c2)CC1)S(=O)(=O)c1ccc(OC)cc1 -US20040122244A1,7,COC1=C(OC)C(=O)C(Cc2cccc(C(=O)Nc3cccnc3)c2OC(C)=O)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2cccc(C(=O)Nc3cccnc3)c2O)=C(C)C1=O -US05773620,1,CC(C)I.O=Cc1cccc(O)c1>>CC(C)Oc1cccc(C=O)c1 -US04885298,3,CC(=O)Nc1cccc(C=O)c1.O=C1CC(c2ccccc2)Oc2ccccc21>>CC(=O)Nc1cccc(C=C2C(=O)c3ccccc3OC2c2ccccc2)c1 -US08642620B2,7,COC(=O)C=Cc1ccc(-c2ccc(F)cc2)nc1>>OCC=Cc1ccc(-c2ccc(F)cc2)nc1 -US20030186976A1,2,Cc1c(-c2cc3ccccc3o2)oc(=O)c(C)c1O.O=C(Cl)c1ccccc1>>Cc1c(-c2cc3ccccc3o2)oc(=O)c(C)c1OC(=O)c1ccccc1 -US05633287,1,CC(C)c1cc(C(C)C)c(O)c(C(C)C)c1.O=C(O)CBr>>CC(C)c1cc(C(C)C)c(OCC(=O)O)c(C(C)C)c1 -US20150099770A1,2,CCC[C@@H](CCOC(C)=O)Nc1nc(N)nc(C)c1Cc1ccc(OCCCO)cc1OC.CS(=O)(=O)Cl>>CCC[C@@H](CCOC(C)=O)Nc1nc(N)nc(C)c1Cc1ccc(OCCCOS(C)(=O)=O)cc1OC -US06288082B1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Nc1cccc2[nH]ccc12>>COc1cc2ncc(C#N)c(Nc3cccc4[nH]ccc34)c2cc1OC -US04377587,1,CCOCC(=O)Nc1c(C)ccc([N+](=O)[O-])c1C.COC(=O)C(C)Br>>CCOCC(=O)N(c1c(C)ccc([N+](=O)[O-])c1C)C(C)C(=O)OC -US09096600B2,1,CCOC(C)n1cc(-c2c(C)c(Cl)cc(C(C)=O)c2-c2cccc(F)c2)cn1.[NH4+]>>CCOC(C)n1cc(-c2c(C)c(Cl)cc(C(C)N)c2-c2cccc(F)c2)cn1 -US07989438B2,2,NS(=O)(=O)N1CCN(CCCC2COc3ccccc3-c3c(C4CCCCC4)c4ccc(C(=O)O)cc4n3C2)CC1>>O=C1NS(=O)(=O)N2CCN(CCCC3COc4ccccc4-c4c(C5CCCCC5)c5ccc1cc5n4C3)CC2 -US20120010228A1,1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccc(F)cc3)C3(CCNCC3)C2=O)c1.CC1(C)C(=O)N(CCCCl)c2ccccc21>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccc(F)cc3)C3(CCN(CCCN4C(=O)C(C)(C)c5ccccc54)CC3)C2=O)c1 -US20050131014A1,7,O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1ccccc1>>FC(F)(F)c1cccc2c(-c3ccccc3)c(Cc3ccccc3)cnc12 -US06225318B1,3,C#Cc1ccccn1.COc1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2cc1I>>COc1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2cc1C#Cc1ccccn1 -US20060122181A1,4,NC(=S)COC(=O)c1ccccc1.O=C(O)c1ccc(C(=O)CBr)cc1>>O=C(O)c1ccc(-c2csc(COC(=O)c3ccccc3)n2)cc1 -US20100076021A1,3,C=CC(=O)OC.Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)cnc2Cl)n1>>COC(=O)/C=C/c1ncc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1 -US04968829,1,CCC(C)Oc1ccc(O)cc1.COC(=O)C(C)Br>>CCC(C)Oc1ccc(OC(C)C(=O)OC)cc1 -US20040214868A1,1,CC(=O)O.Cc1ccccc1COc1cc(O)cc(C(=O)O)c1>>CC(=O)Oc1cc(OCc2ccccc2C)cc(C(=O)O)c1 -US05189211,2,NCCSc1ccc(CCC(=O)O)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(O)CCc1ccc(SCCNS(=O)(=O)c2ccc(Cl)cc2)cc1 -US20120232143A1,6,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC/C(C)=C/C(=O)OCC>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC/C(C)=C/C(=O)O -US07468371B2,1,C=O.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(C)CC1 -US20030069445A1,1,O=C1c2ccccc2C(=O)N1CCCBr.Oc1ccc(I)cc1>>O=C1c2ccccc2C(=O)N1CCCOc1ccc(I)cc1 -US20130165483A1,1,CI.COC(=O)c1cc(Cl)[nH]c1Cl>>COC(=O)c1cc(Cl)n(C)c1Cl -US03962244,2,CC1CCC(N)C1.COC(=O)NS(=O)(=O)c1ccc(CC(=O)N2CNc3ccccc3C2=O)cc1>>CC1CCC(NC(=O)NS(=O)(=O)c2ccc(CC(=O)N3CNc4ccccc4C3=O)cc2)C1 -US04366330,7,CCCCC(=O)c1ccc(OC)cc1F>>CCCCCc1ccc(OC)cc1F -US04508727,6,CC(C)(C)OC(=O)[C@@H]1CN(Cc2ccccc2)C(=O)N1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)[C@@H]1CN(Cc2ccccc2)C(=O)N1 -US20100298395A1,8,OCCc1ccccc1F>>O=CCc1ccccc1F -US20130090323A1,3,Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1I.OB(O)c1ccc(C(F)(F)F)cc1>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1ccc(C(F)(F)F)cc1 -US20100278833A1,1,COC(=O)c1sc(-n2cnc3cnccc32)cc1O.Fc1ccccc1CBr>>COC(=O)c1sc(-n2cnc3cnccc32)cc1OCc1ccccc1F -US20040167182A1,6,O=C(NOC1CCCCO1)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CCN(C2CC2)CC1>>O=C(NO)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CCN(C2CC2)CC1 -US20140039030A1,2,CC(C)(C)OC(=O)NCCN.COCCOCCOCCNC(=O)c1ccc2c(c1)C(CO)c1cc(C(=O)O)ccc1-2>>COCCOCCOCCNC(=O)c1ccc2c(c1)C(CO)c1cc(C(=O)NCCNC(=O)OC(C)(C)C)ccc1-2 -US08178314B2,6,Nc1nc(Cl)cc(OCc2ccc(CNC(=O)C(F)(F)F)cc2)n1>>NCc1ccc(COc2cc(Cl)nc(N)n2)cc1 -US20100093825A1,1,CCI.O=C(NC12CCC(C(=O)O)(CC1)CC2)OCc1ccccc1>>CCOC(=O)C12CCC(NC(=O)OCc3ccccc3)(CC1)CC2 -US08816090B2,9,CC(C)COc1cccc(F)c1C=O.NO>>CC(C)COc1cccc(F)c1C=NO -US20100041891A1,6,COC(=O)CSc1ccc(F)cc1Br>>O=C(O)CSc1ccc(F)cc1Br -US20100280013A1,1,C/C=C\c1cc(C(OCc2ccccc2)(C(F)(F)F)C(F)(F)F)ccc1N1CCN(C(=O)CBr)CC1.CC1(c2ccc3c(c2)OCC3)NC(=O)NC1=O>>CC=Cc1cc(C(OCc2ccccc2)(C(F)(F)F)C(F)(F)F)ccc1N1CCN(C(=O)CN2C(=O)NC(C)(c3ccc4c(c3)OCC4)C2=O)CC1 -US07589232B2,2,CCCCc1ccc(C#Cc2ccc(CNc3ccc4c(c3)C(=O)OC(C)(C)O4)cc2)cc1.O=C(Cl)c1cc2ccccc2s1>>CCCCc1ccc(C#Cc2ccc(CN(C(=O)c3cc4ccccc4s3)c3ccc4c(c3)C(=O)OC(C)(C)O4)cc2)cc1 -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.Cc1ccccc1C(=O)N=C=S>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccccc4C)c(C)c3C)c2cc1OC -US07220744B2,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2nc(-c3ccccc3)ns2)CC1 -US20030017278A1,1,C1=COCCC1.OCCCCBr>>BrCCCCOC1CCCCO1 -US20080293706A1,3,Cn1cc(-c2cnc3ccc(B4OC(C)(C)C(C)(C)O4)cc3n2)cn1.O=S(=O)(Nc1cncc(Br)c1)c1ccc(F)cc1F>>Cn1cc(-c2cnc3ccc(-c4cncc(NS(=O)(=O)c5ccc(F)cc5F)c4)cc3n2)cn1 -US20070265298A1,2,COC(=O)[C@@H](N)C(C)C.Cc1cc(-c2ccc([N+](=O)[O-])cc2)ccc1C(=O)O>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1C)C(C)C -US20090181942A1,6,COC(=O)C1CN(C(=O)CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)C1>>COc1cccc([C@H]2O[C@H](CCC(=O)N3CC(C(=O)O)C3)c3cccn3-c3ccc(Cl)cc32)c1OC -US08987273B2,3,C=CB1OB(C=C)OB(C=C)O1.Cc1nc2cc(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nn2c1Br>>C=Cc1c(C)nc2cc(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nn12 -US08153658B2,6,C[C@H](c1cccc2ccccc12)N(CC1CN(c2c(F)cc(C(=O)O)cc2F)CCC1c1ccccc1)C(=O)OC(C)(C)C>>C[C@@H](NCC1CN(c2c(F)cc(C(=O)O)cc2F)CCC1c1ccccc1)c1cccc2ccccc12 -US20040132716A1,2,CCOC(=O)CN1CCC(C2CCNCC2)CC1.CCc1ccc(C[C@@H](NC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc1CC>>CCOC(=O)CN1CCC(C2CCN(C(=O)[C@@H](Cc3ccc(CC)c(CC)c3)NC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1 -US20120035237A1,6,COC(=O)c1ccn(Cc2cc(Cl)ccc2OCc2ccccc2)n1>>O=C(O)c1ccn(Cc2cc(Cl)ccc2OCc2ccccc2)n1 -US08673891B2,1,C[C@H](Nc1cc(-c2cnn(COCC[Si](C)(C)C)c2)cc(Cl)n1)c1ccc(F)cc1.Nc1cnccn1>>C[C@H](Nc1cc(-c2cnn(COCC[Si](C)(C)C)c2)cc(Nc2cnccn2)n1)c1ccc(F)cc1 -US20110076291A1,6,CC(C)(Cn1cc(-c2ccc3c(c2)OCCc2sc(-c4ncnn4CC(F)(F)F)nc2-3)cn1)NC(=O)OC(C)(C)C>>CC(C)(N)Cn1cc(-c2ccc3c(c2)OCCc2sc(-c4ncnn4CC(F)(F)F)nc2-3)cn1 -US20150080438A1,1,CNCCCCCCS(=O)(=O)CCCC(F)(F)C(F)(F)F.Oc1ccc2c(c1)CCCC(c1ccc(F)c(O)c1)=C2CCCCCCBr>>CN(CCCCCCC1=C(c2ccc(F)c(O)c2)CCCc2cc(O)ccc21)CCCCCCS(=O)(=O)CCCC(F)(F)C(F)(F)F -US20130072679A1,2,CCC(=O)Cl.CN1C(=O)CCc2cc(-c3cncc(CN)c3Cl)ccc21>>CCC(=O)NCc1cncc(-c2ccc3c(c2)CCC(=O)N3C)c1Cl -US20090062291A1,1,COc1cc2nncc(-c3cnc(F)c(C)c3)c2cc1OC.NC1CCCc2ncccc21>>COc1cc2nncc(-c3cnc(NC4CCCc5ncccc54)c(C)c3)c2cc1OC -US07138414B2,7,COc1cc(-c2nnc(C)[nH]2)ccc1[N+](=O)[O-]>>COc1cc(-c2nnc(C)[nH]2)ccc1N -US06706738B2,2,CC(=O)Oc1cc(CC(=O)O)ccc1[N+](=O)[O-].CCOC(=O)CC(C)c1ccc(N)cn1>>CCOC(=O)CC(C)c1ccc(NC(=O)Cc2ccc([N+](=O)[O-])c(OC(C)=O)c2)cn1 -US20100120801A1,3,O=C1Cc2c(Cl)ncnc2N1.O=Cc1nccs1>>O=C1Nc2ncnc(Cl)c2C1=Cc1nccs1 -US03983239,1,Cc1ccc2c(c1)C1CNCCC1N2.ClCc1ccccc1>>Cc1ccc2c(c1)C1CN(Cc3ccccc3)CCC1N2 -US20070049618A1,2,COc1ccc(C(=O)Cl)cc1.NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O>>COc1ccc(C(=O)NCc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1 -US08148383B2,1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2F)c(=O)[nH]c2ncnn12.OB(O)c1ccccc1>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2F)c(=O)n(-c2ccccc2)c2ncnn12 -US20140031368A1,2,COC(=O)CCCCCCNC(=O)c1ccc(C(C(=O)Nc2cccc3cccnc23)C(=O)Nc2cccc3cccnc23)cc1.NO>>O=C(CCCCCCNC(=O)c1ccc(C(C(=O)Nc2cccc3cccnc23)C(=O)Nc2cccc3cccnc23)cc1)NO -US20070043013A1,6,CC(C)(C)OC(=O)NC1(CCN2CC(Oc3ccc(Cl)cc3)C2)CCC1>>NC1(CCN2CC(Oc3ccc(Cl)cc3)C2)CCC1 -US20060089367A1,2,COCCC(=O)O.Fc1cc2nc(COc3ccccc3)n(Cc3ccc(OC(F)(F)F)cc3)c2cc1N1CCNCC1>>COCCC(=O)N1CCN(c2cc3c(cc2F)nc(COc2ccccc2)n3Cc2ccc(OC(F)(F)F)cc2)CC1 -US05811548,7,COc1ccc2c(c1)Sc1c(ccc(OC)c1C=O)N2Cc1ccccc1>>COc1ccc2c(c1)Sc1c(ccc(OC)c1CO)N2Cc1ccccc1 -US20110028467A1,1,COC(=O)CO.O=[N+]([O-])c1cc(C(F)(F)F)cnc1Cl>>COC(=O)COc1ncc(C(F)(F)F)cc1[N+](=O)[O-] -US20040162287A1,7,N#CCc1csc2ccccc12>>NCCc1csc2ccccc12 -US04018802,3,C#CC1(OC(C)=O)CCCCC1.C=O.CCNCC>>CCN(CC)CC#CC1(OC(C)=O)CCCCC1 -US20100292210A1,1,O[C@@H](CNCc1ncc(Cl)nc1Cl)c1ccccc1>>Clc1cnc2c(n1)O[C@H](c1ccccc1)CNC2 -US20140058098A1,1,CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(Cl)cc1OCC2.C[C@H](N)C(N)=O>>CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(N[C@@H](C)C(N)=O)cc1OCC2 -US20030045546A1,4,O=C(NNC(=O)c1sccc1Cl)c1cccnc1>>Clc1ccsc1-c1nnc(-c2cccnc2)o1 -US08569317B2,1,C#CCOc1ccc(N)c(C(=O)c2ccc(C3CC3)cc2)c1.O=Cc1ccccc1>>C#CCOc1ccc(NCc2ccccc2)c(C(=O)c2ccc(C3CC3)cc2)c1 -US20150119373A1,2,C1CCNCC1.CC(C)(C)OC(=O)N[C@@H]1C[C@H](C(=O)O)C1(C)C>>CC(C)(C)OC(=O)N[C@@H]1C[C@H](C(=O)N2CCCCC2)C1(C)C -US20130172328A1,1,CCI.O=c1[nH]c2cccnc2n1-c1ccc(-n2ncc3cccnc32)cc1>>CCn1c(=O)n(-c2ccc(-n3ncc4cccnc43)cc2)c2ncccc21 -US20140005213A1,4,CC(C)Oc1cccc2ccc(C=O)nc12.NNc1ccc([C@H](N2CC[C@@H](O)C2)C(F)(F)F)cn1>>CC(C)Oc1cccc2ccc(-c3nnc4ccc([C@H](N5CC[C@@H](O)C5)C(F)(F)F)cn34)nc12 -US04801610,2,CC(C)(C)C(=O)Cl.O=C(c1ccc(O)cc1)c1ccc(Cl)cc1>>CC(C)(C)C(=O)Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1 -US20140241985A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccc(C(=O)O)cc1>>CC(C)(C)OC(=O)NCCc1ccc(C(=O)O)cc1 -US05990142,4,N#Cc1cc(=O)c2cccc([N+](=O)[O-])c2o1.[N-]=[N+]=[N-]>>O=c1cc(-c2nnn[nH]2)oc2c([N+](=O)[O-])cccc12 -US05463073,1,CCSc1nc2c(C)sc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCSc1nc2c(C)sc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20150018363A1,1,Cc1nc2ccc(-n3ccc(O)cc3=O)cc2n1C.OCc1csc(C(F)(F)F)c1>>Cc1nc2ccc(-n3ccc(OCc4csc(C(F)(F)F)c4)cc3=O)cc2n1C -US06458781B1,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US20070173498A1,2,COC(=O)c1ccc(C(=O)O)cc1.Nc1ccccc1>>COC(=O)c1ccc(C(=O)Nc2ccccc2)cc1 -US06239151B1,6,CC(C)CC(C(=O)NN(CC(C)C)C(=O)CN1CCCC1)[C@H](CC=Cc1ccccc1)C(=O)NOC1CCCCO1>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)CN1CCCC1)[C@H](C/C=C/c1ccccc1)C(=O)NO -US06825199B2,1,CC(C)(C)OC(=O)NC1CCNC1.O=c1c2cc(F)c(F)cc2n(-c2ccc(F)cc2)c(=O)n1OCc1ccccc1>>CC(C)(C)OC(=O)NC1CCN(c2cc3c(cc2F)c(=O)n(OCc2ccccc2)c(=O)n3-c2ccc(F)cc2)C1 -US20110003874A1,1,ClCc1nn(Cc2ccccc2)c2ccccc12.OCCCO>>OCCCOCc1nn(Cc2ccccc2)c2ccccc12 -US08247403B2,3,CC(C)(C)OC(=O)N1CCOc2c(Br)cccc2C1.COc1ccccc1B(O)O>>COc1ccccc1-c1cccc2c1OCCN(C(=O)OC(C)(C)C)C2 -US06875767B2,1,CC(C)(C)[SiH2]OC(C)(C)c1cc(N)nc(Cl)c1.N#Cc1cnc(Cl)s1>>CC(C)(C)[SiH2]OC(C)(C)c1cc(Cl)nc(Nc2ncc(C#N)s2)c1 -US05789423,1,COc1ccc(C(C)(C)CC#N)cc1C=O.N[C@H]1CCCN[C@H]1c1ccccc1>>COc1ccc(C(C)(C)CC#N)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 -US20040235905A1,7,COc1cccc(C2CCc3cc(Oc4ccc([N+](=O)[O-])cn4)ccc3O2)c1>>COc1cccc(C2CCc3cc(Oc4ccc(N)cn4)ccc3O2)c1 -US20040235835A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(N)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)Nc1cc(N)cc(C(F)(F)F)c1 -US20040142821A1,7,N#CC(C#N)=Cc1cccc(Cl)c1Cl>>N#CC(C#N)Cc1cccc(Cl)c1Cl -US20110207731A1,1,CNCCCOC.C[Si](C)(C)CCOCn1nc(Cl)c2cc(C3OCCCO3)ccc21>>COCCCN(C)c1nn(COCC[Si](C)(C)C)c2ccc(C3OCCCO3)cc12 -US07939544B2,1,O=C1CC2CCCC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1.c1ccc(C2CCNCC2)cc1>>O=C(N1CCc2ncc(C(F)(F)F)cc2C1)C12CCCC1CC(N1CCC(c3ccccc3)CC1)C2 -US20120094979A1,3,CCc1c(Br)cccc1Br.CN(C)C=O>>CCc1c(Br)cccc1C=O -US08791102B2,2,O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccccc2F)CN1.O=C(O)Cn1nccn1>>O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccccc2F)CN1C(=O)Cn1nccn1 -US06399629B1,2,CC(C)(C)OC(=O)N1C[C@H](N)C[C@H]1C(=O)Nc1cnc2ccccc2c1.O=C(O)[C@H](O)CCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@H](NC(=O)[C@H](O)CCc2ccccc2)C[C@H]1C(=O)Nc1cnc2ccccc2c1 -US20110172216A1,3,CC1(C)OB(c2ccc3c(c2)OCO3)OC1(C)C.COc1cccc(Nc2nc(Cl)nc3c2cnn3C)c1>>COc1cccc(Nc2nc(-c3ccc4c(c3)OCO4)nc3c2cnn3C)c1 -US20090124607A1,2,C[C@@H](CO)N1C(=O)c2ccccc2C1=O.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](C)N2C(=O)c3ccccc3C2=O)cc1 -US20120277229A1,7,CC1CN(c2ccc3[nH]c(-c4nn(C5CCCCO5)c5ccc([N+](=O)[O-])cc45)nc3c2)CCO1>>CC1CN(c2ccc3[nH]c(-c4nn(C5CCCCO5)c5ccc(N)cc45)nc3c2)CCO1 -US20090131444A1,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CO)OC1.COc1ccc2ncc(Cl)c(O)c2c1>>COc1ccc2ncc(Cl)c(OC[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CO3)c2c1 -US20020165259A1,1,CC(C)(C)c1cnc(CCl)o1.CCOP(OCC)OCC>>CCOP(=O)(Cc1ncc(C(C)(C)C)o1)OCC -US07649093B2,1,COc1ccc2c(O)c(-c3ccccc3)c(C(C)C)cc2c1.O=Cc1ccc(F)cc1>>COc1ccc2c(Oc3ccc(C=O)cc3)c(-c3ccccc3)c(C(C)C)cc2c1 -US20120289522A1,2,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CN)cc3)cc2)CC1.O=C=NCc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CNC(=O)NCc4ccccc4)cc3)cc2)CC1 -US05493028,9,Cc1ccnc(Cl)c1C(=O)O.N>>Cc1ccnc(Cl)c1C(N)=O -US08415370B2,1,N=C(c1ccccc1)c1ccccc1.O=C1N(Cc2cccc(Cl)n2)c2ccccc2C12COc1cc3c(cc12)OCCO3>>O=C1N(Cc2cccc(N=C(c3ccccc3)c3ccccc3)n2)c2ccccc2C12COc1cc3c(cc12)OCCO3 -US20150284359A1,7,O=C1NCc2c1cccc2[N+](=O)[O-]>>Nc1cccc2c1CNC2=O -US06821967B2,2,COC(=O)CN.O=C(O)C1(CCCCBr)c2ccccc2-c2ccccc21>>COC(=O)CNC(=O)C1(CCCCBr)c2ccccc2-c2ccccc21 -US20070010511A1,2,CC(=O)Cl.Cc1ccc(CO)cc1N>>CC(=O)Nc1cc(CO)ccc1C -US07205300B2,1,CCCI.Cc1nc2cc3c(cc2[nH]1)C1CC3CN(C(=O)OC(C)(C)C)C1>>CCCn1c(C)nc2cc3c(cc21)C1CC3CN(C(=O)OC(C)(C)C)C1 -US07132457B2,1,NCCOCCO.O=Cc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(CNCCOCCO)ccc1Cl -US06228853B1,2,O=C(Cl)OCc1ccccc1.O=C(O)C1CNC1>>O=C(O)C1CN(C(=O)OCc2ccccc2)C1 -US07625886B2,2,CCOC(=O)CN1CCN(C2CCNCC2)CC1.Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc2oc(=O)[nH]c12>>CCOC(=O)CN1CCN(C2CCN(C(=O)[C@@H](Cc3cc(C)c4[nH]c(=O)oc4c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1 -US08952169B2,2,COCCS(N)(=O)=O.O=C(O)c1cc(C2CC2)c(OCC2CCCC2)cc1F>>COCCS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCCC2)cc1F -US20080076774A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCC(CC)COc1cc(Br)c(C)c(Br)c1>>CCC(CC)COc1cc(Br)c(C)c(N2CCN(C(=O)OC(C)(C)C)CC2)c1 -US05045228,1,CCCCCCCCCCBr.N#Cc1ccc(-c2ccc(O)cc2)cc1>>CCCCCCCCCCOc1ccc(-c2ccc(C#N)cc2)cc1 -US08367696B2,6,CCOC(=O)c1nc(Cl)sc1-c1ccccc1>>O=C(O)c1nc(Cl)sc1-c1ccccc1 -US07858781B2,2,COc1cccc2oc(C(=O)O)cc12.NC1CCN(CCN2CCCCCC2)CC1>>COc1cccc2oc(C(=O)NC3CCN(CCN4CCCCCC4)CC3)cc12 -US05801168,6,COc1c(-c2ccc([N+](=O)[O-])cc2)c(=O)c2ccc(Cl)cc2[nH]c1=O>>O=c1[nH]c2cc(Cl)ccc2c(=O)c(-c2ccc([N+](=O)[O-])cc2)c1O -US20100204196A1,7,CN(C)CC(=O)N1CCc2cc(N(C)C)c([N+](=O)[O-])cc21>>CN(C)CC(=O)N1CCc2cc(N(C)C)c(N)cc21 -US03933794,8,Cc1cnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2.O=C(OO)c1cccc(Cl)c1>>Cc1cnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=[N+]([O-])C2 -US06479531B1,1,Cc1ccccc1-c1nc(C(=O)O)c(CCC23CC4CC(CC(C4)C2)C3)[nH]1.O=C(OCc1ccccc1)c1cccc(O)c1>>Cc1ccccc1-c1nc(C(=O)Oc2cccc(C(=O)OCc3ccccc3)c2)c(CCC23CC4CC(CC(C4)C2)C3)[nH]1 -US20030139409A1,2,CN(C)CCN.CSc1cccc2c1ccc1nc3cccc(C(=O)O)c3nc12>>CSc1cccc2c1ccc1nc3cccc(C(=O)NCCN(C)C)c3nc12 -US20150164876A1,2,NCCN1CCOCC1.O=C(O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>O=C(NCCN1CCOCC1)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1 -US08415272B2,2,C#Cc1cnc2ccc(OC(SC)C(=O)O)cc2c1.COCC(C)(N)CO>>C#Cc1cnc2ccc(OC(SC)C(=O)NC(C)(CO)COC)cc2c1 -US20100227859A1,3,CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(Br)cc12)C(=O)OC(C)(C)C.OB(O)c1cccnc1>>CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(-c3cccnc3)cc12)C(=O)OC(C)(C)C -US20130023541A1,1,CC(C)OC(=O)c1cccnc1N1CCNCC1.O=Cc1cccc(O)c1>>CC(C)OC(=O)c1cccnc1N1CCN(Cc2cccc(O)c2)CC1 -US08044242B2,1,CI.O=C(NCc1ccccc1SC1CC1)C(F)(F)F>>CN(Cc1ccccc1SC1CC1)C(=O)C(F)(F)F -US20110039824A1,6,COC(=O)c1ccc(OCc2ccccc2)cc1>>O=C(O)c1ccc(OCc2ccccc2)cc1 -US06472545B2,6,COC(=O)[C@@H](Cc1ccccc1)Oc1c(Cl)cc(-c2cccc3c2oc2ccccc23)cc1Cl>>O=C(O)[C@@H](Cc1ccccc1)Oc1c(Cl)cc(-c2cccc3c2oc2ccccc23)cc1Cl -US05559113,1,ClCCc1c[nH]cn1.Oc1cccc2ccccc12>>c1ccc2c(OCCc3c[nH]cn3)cccc2c1 -US07687515B2,1,CCOc1ccc(-c2cc3[nH]cnc3c(C#N)n2)cc1C(F)(F)F.OCCBr>>CCOc1ccc(-c2cc3c(ncn3CCBr)c(C#N)n2)cc1C(F)(F)F -US20140275084A1,1,CN1CCOC(CCl)C1.N#Cc1ccnc(-c2c[nH]cn2)c1>>CN1CCOC(Cn2cnc(-c3cc(C#N)ccn3)c2)C1 -US08129397B2,1,CI.Cc1cc2c(=O)[nH]c(Cn3cc(CO)c(C(F)(F)F)n3)nc2s1>>Cc1cc2c(=O)n(C)c(Cn3cc(CO)c(C(F)(F)F)n3)nc2s1 -US06225306B1,6,CC(C)(C)[Si](C)(C)O[C@@H]1C[C@H]2CN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c3ccccc3C(=O)N2C1>>O=C(Nc1ccc(C(=O)N2C[C@@H]3C[C@@H](O)CN3C(=O)c3ccccc32)cc1)c1ccccc1-c1ccccc1 -US20080286231A1,2,Nc1ccc2[nH]cnc2c1.S=C=NCc1ccccc1>>S=C(NCc1ccccc1)Nc1ccc2[nH]cnc2c1 -US20140296252A1,1,Cc1cc([N+](=O)[O-])nc(C)c1Br.Oc1ccnc(Cl)c1>>Cc1cc([N+](=O)[O-])nc(C)c1Oc1ccnc(Cl)c1 -US20030105151A1,3,COc1cccc(-c2ccc3c(c2)NC(=O)C3)c1.Cc1[nH]c(C=O)c(C)c1CCC(=O)O>>COc1cccc(-c2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C)c(CCC(=O)O)c2C)c1 -US20060189601A1,6,COc1ccc2nccc(N3C[C@@H]4C[C@H]3CN4CCNC(=O)OCc3ccccc3)c2n1>>COc1ccc2nccc(N3C[C@@H]4C[C@H]3CN4CCN)c2n1 -US20150284391A1,3,C=CC(=O)OC.COc1cc(Br)ccc1Cl>>COC(=O)/C=C/c1ccc(Cl)c(OC)c1 -US20140275553A1,3,COc1nc(Cl)nc(OC)c1[N+](=O)[O-].Fc1ccc(C[Zn+])cc1>>COc1nc(Cc2ccc(F)cc2)nc(OC)c1[N+](=O)[O-] -US06271261B1,2,C[C@H](N=C=O)c1ccccc1.Nc1ccc([N+](=O)[O-])cc1O>>C[C@H](NC(=O)Nc1ccc([N+](=O)[O-])cc1O)c1ccccc1 -US06355662B1,6,CCOC(OCC)c1cc(C(CC(C)C)NC(=O)OCc2ccccc2)no1>>CC(C)CC(NC(=O)OCc1ccccc1)c1cc(C=O)on1 -US20100160255A1,6,CCN1C(=O)OC2(CCCN(C3CCN(C(=O)c4c(NC(=O)OC(C)(C)C)sc5ccccc45)CC3)C2)C1=O>>CCN1C(=O)OC2(CCCN(C3CCN(C(=O)c4c(N)sc5ccccc45)CC3)C2)C1=O -US06919315B1,6,CN(C)C[C@@H]1CCCN(C(=O)[C@@H](Cc2ccccc2)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)OC(C)(C)C)C1>>CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H](CN(C)C)C1 -US07498460B2,1,BrCCCc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1.CCOC(=O)c1ccc(O)c(C=O)c1>>CCOC(=O)c1ccc(OCCCc2ccc(OCc3ccc(-c4ccccc4)cc3)cc2)c(C=O)c1 -US20120277279A1,2,NCC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F.O=C(O)c1c(Br)cccc1Br>>Nc1c(C(=O)NCC(O)(CNC(=O)c2c(Br)cccc2Br)C(F)(F)F)cnn1-c1ccc(F)cc1 -US05620979,7,CNc1ccccc1[N+](=O)[O-]>>CNc1ccccc1N -US06075029,1,CC(=O)O[C@H](C)CCCCI.Cc1nc2c(c(=O)[nH]c(=O)n2Cc2ccco2)n1COC(=O)C(C)(C)C>>CC(=O)O[C@H](C)CCCCn1c(=O)c2c(nc(C)n2COC(=O)C(C)(C)C)n(Cc2ccco2)c1=O -US08198456B2,6,CC1=C(C#N)C(c2ccc3c(c2)c(C)nn3C(=O)OC(C)(C)C)C(C#N)=C(C)N1C>>CC1=C(C#N)C(c2ccc3[nH]nc(C)c3c2)C(C#N)=C(C)N1C -US20150252038A1,2,NS(=O)(=O)C1CC1.O=C(O)c1cc(C2CC2)c(OCC2CCN(Cc3cc(C(F)(F)F)cc(Cl)c3F)CC2)cc1F>>O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(OCC2CCN(Cc3cc(C(F)(F)F)cc(Cl)c3F)CC2)cc1F -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1[C@H](O)CSCc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4[C@H](O)CSCc4ccccc4)cc3)cc2)CC1 -US06756388B1,3,COc1ccc(-c2cc3ccc(OC)cc3s2)cc1.O=C(Cl)c1ccc(I)cc1>>COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(I)cc2)cc1 -US06344562B1,6,CCOC(=O)CC(NC(=O)c1cc(NC(=O)c2sc(NC(=N)N)nc2C)ccc1OCCOC)c1ccccc1>>COCCOc1ccc(NC(=O)c2sc(NC(=N)N)nc2C)cc1C(=O)NC(CC(=O)O)c1ccccc1 -US20050131015A1,2,CCOC(=O)O/N=C(\N)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21>>O=C(NC1Cc2ccccc2N(Cc2noc(=O)[nH]2)C1=O)c1cc2cc(Cl)sc2[nH]1 -US20020049322A1,3,COc1cc2nc(N3CCc4ncccc4C3)nc(N)c2c(I)c1OC.COc1ccccc1B(O)O>>COc1ccccc1-c1c(OC)c(OC)cc2nc(N3CCc4ncccc4C3)nc(N)c12 -US20150065507A1,7,Cc1nc(N2CCOC2=O)ccc1[N+](=O)[O-]>>Cc1nc(N2CCOC2=O)ccc1N -US08609848B2,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OC.O=S(=O)(Cl)c1ccc(Cl)cc1>>COc1ccc(C2=NN(C3CCN(S(=O)(=O)c4ccc(Cl)cc4)CC3)C(=O)C2(C)C)cc1OC -US20140005175A1,4,CC(C)(C(=O)NNC(=O)c1ccccc1)c1ccc(S(=O)(=O)/C=C/C#N)cc1>>CC(C)(c1ccc(S(=O)(=O)/C=C/C#N)cc1)c1nnc(-c2ccccc2)o1 -US20100113780A1,1,CC(C)(C)[Si](C)(C)OC1CCc2ccc(B(O)O)cc21.CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCCc1nc(C)n(-c2ccc3c(c2)C(O[Si](C)(C)C(C)(C)C)CC3)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US06638929B2,9,C[Si](C)(C)CCOCn1cc(C#N)c(=O)c2cc([N+](=O)[O-])c(Cl)cc21.[N-]=[N+]=[N-]>>C[Si](C)(C)CCOCn1cc(C#N)c(=O)c2cc([N+](=O)[O-])c(N=[N+]=[N-])cc21 -US08637525B2,1,COc1cc([N+](=O)[O-])ccc1Cl.Clc1c[nH]cn1>>COc1cc([N+](=O)[O-])ccc1-n1cnc(Cl)c1 -US20100056491A1,6,COC1CCN(c2cccc(S(=O)(=O)n3cc(C4=CCC(NC(=O)OC(C)(C)C)CC4)c4ncccc43)c2)C1>>COC1CCN(c2cccc(S(=O)(=O)n3cc(C4=CCC(N)CC4)c4ncccc43)c2)C1 -US20100222346A1,1,COc1cccc2c(Cl)cc(C)nc12.C[C@@H](N)c1ccc(Cl)cc1>>COc1cccc2c(N[C@H](C)c3ccc(Cl)cc3)cc(C)nc12 -US05109013,1,CN1CC(CCCl)N(C)c2nc3ccccc3n2C1=O.Fc1ccc(C(c2ccc(F)cc2)C2CCNCC2)cc1>>CN1CC(CCN2CCC(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)N(C)c2nc3ccccc3n2C1=O -US20120010189A1,2,CS(=O)(=O)Cl.O=C(c1nnc(-c2ccccc2)o1)N1CC(O)C1>>CS(=O)(=O)OC1CN(C(=O)c2nnc(-c3ccccc3)o2)C1 -US06949577B2,3,CON(C)C(=O)[C@H](C)NC(=O)OC(C)(C)C.C[Mg+]>>CC(=O)[C@H](C)NC(=O)OC(C)(C)C -US07674773B2,1,CNCC(O)C(O)C(O)C(O)CO.O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(OCCCCCI)cc2)N1c1ccc(F)cc1>>CN(CCCCCOc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1)CC(O)C(O)C(O)C(O)CO -US08048904B2,1,BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCCc1nc(C(C)(C)O)c(C(=O)OCC)[nH]1>>CCCc1nc(C(C)(C)O)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20130102577A1,9,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](N=[N+]=[N-])CC[C@]4(C)[C@H]3CC[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](N)CC[C@]4(C)[C@H]3CC[C@]12C -US06583126B2,7,O=C(O)c1ccc(CBr)cc1Br>>OCc1ccc(CBr)cc1Br -US07935688B2,6,CCC(CC)(c1ccc(/C=C/C2(O)CCOCC2)c(C)c1)c1ccc(-c2cncc(CC(=O)OC)c2)c(C)c1>>CCC(CC)(c1ccc(/C=C/C2(O)CCOCC2)c(C)c1)c1ccc(-c2cncc(CC(=O)O)c2)c(C)c1 -US20120071481A1,1,CC(C)N.CCOC(=O)c1noc(-c2ccc(C(F)(F)F)cc2)c1CBr>>CCOC(=O)c1noc(-c2ccc(C(F)(F)F)cc2)c1CNC(C)C -US20090093484A1,3,C#CCN(C)C.CCOC(=O)/C=C(\c1ccccc1)c1ccc(Br)cc1>>CCOC(=O)/C=C(\c1ccccc1)c1ccc(C#CCN(C)C)cc1 -US04584293,2,COc1cc(CC(=O)O)c([N+](=O)[O-])cc1OC.COc1ccc2c(c1)CC(N(C)CCCN)CC2>>COc1ccc2c(c1)CC(N(C)CCCNC(=O)Cc1cc(OC)c(OC)cc1[N+](=O)[O-])CC2 -US20090197859A1,2,CN1CCC(c2cccc(C(=O)O)n2)CC1.Cc1ccccc1OC1CCNCC1>>Cc1ccccc1OC1CCN(C(=O)c2cccc(C3CCN(C)CC3)n2)CC1 -US20060257987A1,3,CCCCB(O)O.COC(=O)CCc1ccc(OCCC(C)Oc2ccc(Br)cc2C(=O)c2ccccc2)cc1C>>CCCCc1ccc(OC(C)CCOc2ccc(CCC(=O)OC)c(C)c2)c(C(=O)c2ccccc2)c1 -US04845188,3,CCOC(=O)CC(=O)OCC.CSc1ccc(C=O)cc1>>CCOC(=O)C(=Cc1ccc(SC)cc1)C(=O)OCC -US20150141427A1,2,Nc1ccc(OC(F)(F)F)cc1.O=C(O)c1cccc(Br)c1F>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(Br)c1F -US20070185079A1,1,COc1ccc2nc(Cl)cc(C)c2c1.N[C@H]1C[C@H]2C[C@H](N(Cc3ccccc3)C(=O)OCc3ccccc3)[C@@H]1C2>>COc1ccc2nc(N[C@H]3C[C@H]4C[C@H](N(Cc5ccccc5)C(=O)OCc5ccccc5)[C@@H]3C4)cc(C)c2c1 -US20100249163A1,1,BrCc1ccccc1.Oc1cc(Br)ccn1>>Brc1ccnc(OCc2ccccc2)c1 -US05891889,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.Cc1cccc([Mg+])c1>>Cc1cccc(C2(O)CCN(C(=O)OC(C)(C)C)CC2)c1 -US20110053935A1,3,C[Mg+].N#Cc1ccc2nccc(C=O)c2c1>>CC(O)c1ccnc2ccc(C#N)cc12 -US20020115853A1,6,COc1cc(-c2cccc([N+](=O)[O-])c2)ccc1N>>Nc1ccc(-c2cccc([N+](=O)[O-])c2)cc1O -US06429297B1,5,NCCCCCC(=O)O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)CCCCCNC(=O)C(F)(F)F -US20060004017A1,6,COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OC[C@@H](CN1CCCC1)OC(C)=O>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OC[C@H](O)CN1CCCC1 -US20130338196A1,6,CC(C)(C)[Si](C)(C)OC(c1ncc(-c2ccccn2)o1)C1CCc2cc(Oc3ccccc3)ccc2C1>>OC(c1ncc(-c2ccccn2)o1)C1CCc2cc(Oc3ccccc3)ccc2C1 -US20140296209A1,3,CNC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cn1.Cc1ccc2c(c1)c1c(n2-c2cccc(Br)c2)CCN(C)C1>>CNC(=O)c1ccc(-c2cccc(-n3c4c(c5cc(C)ccc53)CN(C)CC4)c2)cn1 -US20100152450A1,1,CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(Br)c1.c1ccc(COc2ccc(OCCC3CCNCC3)cc2)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1COc1cncc(N2CCC(CCOc3ccc(OCc4ccccc4)cc3)CC2)c1 -US05773463,1,CC(C)(C)OC(=O)N[C@H]1Cc2ccccc2[C@H]1Oc1ccc(OCc2ccccc2)cc1.CI>>CN(C(=O)OC(C)(C)C)[C@H]1Cc2ccccc2[C@H]1Oc1ccc(OCc2ccccc2)cc1 -US20070254867A1,5,Brc1c[nH]c2cnccc12.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1cc(Br)c2ccncc21 -US06867218B2,7,CCOC(=O)/C=C(\C)c1ccc(-c2cc(OC)ccc2OC)cc1>>COc1ccc(OC)c(-c2ccc(/C(C)=C/CO)cc2)c1 -US06867218B2,6,CCOC(=O)[C@H](Cc1ccc(OC/C(CC)=C(/C)c2ccc(Br)cc2)cc1)OCC>>CCO[C@@H](Cc1ccc(OC/C(CC)=C(/C)c2ccc(Br)cc2)cc1)C(=O)O -US05691330,1,CC(=O)N1CCc2cc(C(=O)CCCCl)sc2C1.Fc1ccc2c(C3CCNCC3)csc2c1>>CC(=O)N1CCc2cc(C(=O)CCCN3CCC(c4csc5cc(F)ccc45)CC3)sc2C1 -US20050282880A1,2,Nc1ccc2c(c(-c3cccc(F)c3)nn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1Br.O=C(Cl)C1CC1>>O=C(Nc1ccc2c(c(-c3cccc(F)c3)nn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1Br)C1CC1 -US06172228B2,1,Clc1ccc(C(c2ccccc2)N2CCNCC2)cc1.O=S(=O)(CCCCCCCl)NCCCCO>>O=S(=O)(CCCCCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1)NCCCCO -US20070173498A1,2,CN(C)CC1CCc2cc(OCc3ccc(N)cc3)ccc2C1.O=C(Cl)Cc1ccccc1>>CN(C)CC1CCc2cc(OCc3ccc(NC(=O)Cc4ccccc4)cc3)ccc2C1 -US07179871B2,1,CC(=O)c1cccc(C(C)=Nc2c(C)cc(C)cc2C)n1.C[Si](C)(C)Oc1ccc(N)cc1>>CC(=Nc1ccc(O[Si](C)(C)C)cc1)c1cccc(C(C)=Nc2c(C)cc(C)cc2C)n1 -US07569704B1,1,CCC1(CC)c2cc(Br)ccc2-c2ccc(-c3cccn3C)cc21.c1ccc(Nc2ccccc2)cc1>>CCC1(CC)c2cc(-c3cccn3C)ccc2-c2ccc(N(c3ccccc3)c3ccccc3)cc21 -US04866196,6,COc1ccc(C(C)CN)c(F)c1>>CC(CN)c1ccc(O)cc1F -US07425568B2,7,O=[N+]([O-])c1ccc(Oc2ccc3c(c2)CCC(c2ccccc2F)O3)nc1>>Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2F)O3)nc1 -US05919943,6,COC(=O)COc1cccc2c1c(C(=O)C(N)=O)c(C1CC1)n2Cc1ccccc1-c1ccccc1>>NC(=O)C(=O)c1c(C2CC2)n(Cc2ccccc2-c2ccccc2)c2cccc(OCC(=O)O)c12 -US20110301353A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCC1)CC2.O=C1Cc2cc(F)ccc2N1>>Cc1c(C=C2C(=O)Nc3ccc(F)cc32)[nH]c2c1C(=O)N(CCN1CCCC1)CC2 -US20030229096A1,7,O=[N+]([O-])c1ccc(Cl)c(C(F)F)c1>>Nc1ccc(Cl)c(C(F)F)c1 -US20020198194A1,1,Cc1cc(N2CCCC2)c2ccc(O)cc2n1.N#Cc1ccccc1CBr>>Cc1cc(N2CCCC2)c2ccc(OCc3ccccc3C#N)cc2n1 -US07160887B1,1,C[C@H](NC(=O)OC(C)(C)C)c1cccc(O)c1.O=[N+]([O-])c1ccc(Cl)cc1F>>C[C@H](NC(=O)OC(C)(C)C)c1cccc(Oc2cc(Cl)ccc2[N+](=O)[O-])c1 -US20120115869A1,3,CCC(=O)N(Cc1ccc(I)cc1)c1cc(F)cc(C#N)c1.Cc1cccc(C)c1B(O)O>>CCC(=O)N(Cc1ccc(-c2c(C)cccc2C)cc1)c1cc(F)cc(C#N)c1 -US20120302596A1,2,O=S(=O)(Cl)c1ccc2ccccc2c1.c1cc2[nH]cc(C3CCN4CCCC4C3)c2cn1>>O=S(=O)(c1ccc2ccccc2c1)n1cc(C2CCN3CCCC3C2)c2cnccc21 -US20090036682A1,1,C=O.O=S(=O)(c1ccccc1)c1cnc2c(N3CCNCC3)cccc2c1>>CN1CCN(c2cccc3cc(S(=O)(=O)c4ccccc4)cnc23)CC1 -US20130237502A1,2,CS(=O)(=O)NCc1ccc(-c2ccc([C@@H](O)[C@@H](CF)NC(=O)C(F)F)cc2)cn1.O=C(Cl)CCCBr>>CS(=O)(=O)NCc1ccc(-c2ccc([C@@H](OC(=O)CCCBr)[C@@H](CF)NC(=O)C(F)F)cc2)cn1 -US05449809,2,C#Cc1ccccc1C(=NOC)C(=O)OC.CN>>C#Cc1ccccc1C(=NOC)C(=O)NC -US07655641B2,1,CCCN(CC(C)O)S(=O)(=O)c1sc2ccc(Cl)cc2c1C.Cc1cc(O)cc(C)c1OCC(=O)OC(C)(C)C>>CCCN(CC(C)Oc1cc(C)c(OCC(=O)OC(C)(C)C)c(C)c1)S(=O)(=O)c1sc2ccc(Cl)cc2c1C -US04446323,7,O=C1Nc2cccnc2N2CCCC12>>c1cnc2c(c1)NCC1CCCN21 -US20040138065A1,7,N#CC(C#N)=Cc1ccc(F)cc1Cl>>N#CC(C#N)Cc1ccc(F)cc1Cl -US20140378487A1,1,O=c1nc(Cl)cc2n1CCc1ccccc1-2.OCCc1ccc(Oc2cccc(C(F)(F)F)c2)cc1>>O=c1nc(OCCc2ccc(Oc3cccc(C(F)(F)F)c3)cc2)cc2n1CCc1ccccc1-2 -US04886822,1,Brc1ccc(Cc2ccncc2)cc1.OCC(F)(F)F>>FC(F)(F)COc1ccc(Cc2ccncc2)cc1 -US08680120B2,1,CCOC(=O)CBr.COc1ccc2c(c1)cc(-c1ccccc1)n2Cc1cccc(O)c1>>CCOC(=O)COc1cccc(Cn2c(-c3ccccc3)cc3cc(OC)ccc32)c1 -US04948781,3,CC(C)CCBr.CCC=C(C)C=O>>CCC=C(C)C(O)CCC(C)C -US08735620B2,2,COc1ccc(C=O)cc1O.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(C=O)cc1OS(=O)(=O)c1ccc(C)cc1 -US20100222335A1,1,N#Cc1ccc(O)cc1.OCCCBr>>N#Cc1ccc(OCCCO)cc1 -US06114390,2,CCOC(=O)Cn1cc(CC(=O)O)c2ccccc21.NC(=O)NCc1ccc(CNC(=O)[C@H](N)CCCNC(N)=N[N+](=O)[O-])cc1>>CCOC(=O)Cn1cc(CC(=O)N[C@H](CCCNC(N)=N[N+](=O)[O-])C(=O)NCc2ccc(CNC(N)=O)cc2)c2ccccc21 -US07582769B2,1,Nc1ncc(Br)s1.c1c[nH]cn1>>Nc1ncc(-n2ccnc2)s1 -US06518268B1,1,O=Cc1cc([N+](=O)[O-])ccc1F.Oc1ccc(S)cc1>>O=Cc1cc([N+](=O)[O-])ccc1Sc1ccc(O)cc1 -US07763621B2,6,CCc1c(NC[C@H](NC(=O)OCC23CC4CC(CC(C4)C2)C3)C(=O)OC(C)(C)C)ncnc1N1CCC(c2ccc3c(n2)NCCC3)CC1>>CCc1c(NC[C@H](NC(=O)OCC23CC4CC(CC(C4)C2)C3)C(=O)O)ncnc1N1CCC(c2ccc3c(n2)NCCC3)CC1 -US20040176361A1,1,C1CCN(CCCCN2CCNCC2)CC1.O=c1[nH]c(Cl)cc2ccc(Br)cc12>>O=c1[nH]c(N2CCN(CCCCN3CCCCC3)CC2)cc2ccc(Br)cc12 -US07087618B2,3,CC(=O)OC(C)=O.COc1ccc(-c2cc3cccc(Cl)n3n2)cc1>>COc1ccc(-c2nn3c(Cl)cccc3c2C(C)=O)cc1 -US05624926,1,CCCc1nc(Cl)c2cc(OC)c(OC)cc2n1.Cc1ccc2c(c1)c(=O)n(C1CCNCC1)c(=O)n2C>>CCCc1nc(N2CCC(n3c(=O)c4cc(C)ccc4n(C)c3=O)CC2)c2cc(OC)c(OC)cc2n1 -US20060074237A1,2,Cc1c(Cl)cccc1S(=O)(=O)Cl.Nc1ccc(Oc2ccccc2)cn1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc(Oc2ccccc2)cn1 -US07514460B2,1,COc1cc2c(Cl)ncnc2cc1O.OCCCN1CCCC1>>COc1cc2c(Cl)ncnc2cc1OCCCN1CCCC1 -US20130190327A1,2,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)N[C@@H](C)C(=O)O[C@H](C)[C@H](N)C(=O)OC.CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)N[C@@H](C)C(=O)O[C@H](C)[C@H](NC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)C(=O)OC -US08455521B2,3,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)c2cccc(Cl)c2)C1.CC(F)(F)CCC[Mg+]>>CC(F)(F)CCC[C@@](O)(c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20140005168A1,3,CC1(C)OB(c2cn[nH]c2)OC1(C)C.C[Si](C)(C)CCOCn1ncc2cnc(Cl)cc21>>C[Si](C)(C)CCOCn1ncc2cnc(-c3cn[nH]c3)cc21 -US08188098B2,1,CC(C)c1noc([C@@H]2CC[C@H](n3ncc4c(Cl)ncnc43)CC2)n1.CS(=O)(=O)c1ccc(O)c(F)c1>>CC(C)c1noc([C@@H]2CC[C@H](n3ncc4c(Oc5ccc(S(C)(=O)=O)cc5F)ncnc43)CC2)n1 -US05321150,1,BrCc1ccccc1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCc2ccccc2)cc1 -US05889012,3,C=C(C)C1CCC(=O)CC1.ICI>>CC1(C2CCC(=O)CC2)CC1 -US20150166549A1,3,Cc1cccc(B(O)O)c1.O=c1oc(CO)c(Br)c2ccccc12>>Cc1cccc(-c2c(CO)oc(=O)c3ccccc23)c1 -US20100324000A1,6,O=c1ccc2c([C@@H](O)CNCCc3ccc(OCC45CC6CC(CC(C6)C4)C5)cc3)ccc(OCc3ccccc3)c2[nH]1>>O=c1ccc2c([C@@H](O)CNCCc3ccc(OCC45CC6CC(CC(C6)C4)C5)cc3)ccc(O)c2[nH]1 -US20120108583A1,7,O=[N+]([O-])c1ccc(C2CC2)cc1>>Nc1ccc(C2CC2)cc1 -US07696240B2,9,CCOC(=O)c1c(C=O)c2cc(F)ccc2n1Cc1cccc2ccccc12.NO>>CCOC(=O)c1c(C=NO)c2cc(F)ccc2n1Cc1cccc2ccccc12 -US20060287329A1,2,Nc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cn1.O=C(O)[C@@H]1CC[C@@H](N2CCCC2=O)CC1>>O=C(Nc1ccc(Cl)cn1)c1cc2ccccc2cc1NC(=O)[C@@H]1CC[C@@H](N2CCCC2=O)CC1 -US08501757B2,2,CN(c1cncnc1)c1cc(N)cc(F)c1.N#Cc1cccc(C(=O)Cl)c1>>CN(c1cncnc1)c1cc(F)cc(NC(=O)c2cccc(C#N)c2)c1 -US20140296256A1,6,COC(=O)c1cc(Cl)ccc1NC(=O)CCCNC(=O)c1cccc(-c2ccoc2)c1>>O=C(CCCNC(=O)c1cccc(-c2ccoc2)c1)Nc1ccc(Cl)cc1C(=O)O -US20150133424A1,7,CC(C)(Oc1cccc([N+](=O)[O-])c1)C(N)=O>>CC(C)(Oc1cccc(N)c1)C(N)=O -US20110046134A1,2,NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1.O=C(O)C1CCN(c2ccccc2)CC1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)C1CCN(c2ccccc2)CC1 -US07176242B2,3,CCCN(CCC)C(=O)c1cc(Br)cc(C(=O)OC)c1.OB(O)c1cccc2cccnc12>>CCCN(CCC)C(=O)c1cc(C(=O)OC)cc(-c2cccc3cccnc23)c1 -US07932272B2,6,O=C(NCc1cccc(OCc2ccccc2)c1)c1ccc2ncccc2c1>>O=C(NCc1cccc(O)c1)c1ccc2ncccc2c1 -US20090018128A1,2,Cc1ccc2c(Cl)ncc(C(=O)O)n12.NCC1CCOCC1>>Cc1ccc2c(Cl)ncc(C(=O)NCC3CCOCC3)n12 -US20090270434A1,1,Clc1ncc(Br)cn1.OC1CCNCC1>>OC1CCN(c2ncc(Br)cn2)CC1 -US09040522B2,2,C1CC2CNCCN2C1.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)N3CCN4CCCC4C3)cn2)c1O -US20080004297A1,1,CNC.COc1ccc(N(C)c2nc(Cl)nc3ccc([N+](=O)[O-])cc23)cc1>>COc1ccc(N(C)c2nc(N(C)C)nc3ccc([N+](=O)[O-])cc23)cc1 -US20050026836A1,1,C[C@H](c1ccccc1)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.N=C(N)N>>C[C@H](c1ccccc1)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1 -US20100311800A1,1,CC(Cl)OC(=O)OCCCC[C@@H](C)O[N+](=O)[O-].CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nc(Cl)c(C(=O)OC(C)OC(=O)OCCCC[C@@H](C)O[N+](=O)[O-])n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US08962834B2,1,COc1cc(N)ccc1-n1cnc(C)c1.OCCNc1ccnc(Cl)n1>>COc1cc(Nc2nccc(NCCO)n2)ccc1-n1cnc(C)c1 -US20110263571A1,1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.Cc1ccc(Br)c(C)c1>>Cc1ccc(N2CCN(C(=O)OC(C)(C)C)C[C@H]2C)c(C)c1 -US08399681B2,3,O=C1CSC(N2CCO[C@H](CO)C2)=N1.O=Cc1ccc2c(cnn2Cc2ncccc2C(F)(F)F)c1>>O=C1N=C(N2CCO[C@H](CO)C2)SC1=Cc1ccc2c(cnn2Cc2ncccc2C(F)(F)F)c1 -US04514408,2,CC1CCN(Cc2cccc(OCCCN)c2)CC1.O=C(O)c1ccc[n+]([O-])c1>>CC1CCN(Cc2cccc(OCCCNC(=O)c3ccc[n+]([O-])c3)c2)CC1 -US20080125468A1,6,COC(=O)CCNC(=O)c1ccc(OCc2ccccc2)cc1>>COC(=O)CCNC(=O)c1ccc(O)cc1 -US20040176422A1,1,N#Cc1ccc(C(F)(F)F)nc1Cl.O[C@H](CCCl)c1ccsc1>>N#Cc1ccc(C(F)(F)F)nc1O[C@H](CCCl)c1ccsc1 -US20130317221A1,3,C#Cc1ccc2cc(OC)ccc2c1.Cc1cc(I)ccc1N>>COc1ccc2cc(C#Cc3ccc(N)c(C)c3)ccc2c1 -US04086219,6,COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1>>COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO -US07989461B2,3,CNc1ncc2cc(B3OC(C)(C)C(C)(C)O3)ccc2n1.Cc1nc(Nc2cccc(OC(F)(F)F)c2)c2ccc(C)c(I)c2n1>>CNc1ncc2cc(-c3c(C)ccc4c(Nc5cccc(OC(F)(F)F)c5)nc(C)nc34)ccc2n1 -US20110003852A1,2,CC(C)N=C=O.CCOC(=O)c1ccc(OCCC2CCNCC2)cc1>>CCOC(=O)c1ccc(OCCC2CCN(C(=O)NC(C)C)CC2)cc1 -US20080004271A1,2,NC(=O)c1sc2ncnc(-c3cccc(N)c3)c2c1N.O=C(Cl)Cc1ccccc1>>NC(=O)c1sc2ncnc(-c3cccc(NC(=O)Cc4ccccc4)c3)c2c1N -US20020156081A1,4,CC(C)(C)OC(=O)N1CCC(=O)CC1.C[S+](C)(C)=O>>CC(C)(C)OC(=O)N1CCC2(CC1)CO2 -US20050004014A1,7,CCCCC1(OC)CCN(c2ccc(-c3nnc(-c4ccc(C(=O)OC)cc4)s3)cc2)CC1>>CCCCC1(OC)CCN(c2ccc(-c3nnc(-c4ccc(CO)cc4)s3)cc2)CC1 -US07709471B2,7,CN1CCC(NC(=O)c2ccc([N+](=O)[O-])c(Cl)c2)CC1>>CN1CCC(NC(=O)c2ccc(N)c(Cl)c2)CC1 -US20140187782A1,1,O=C(O)C(S)=Cc1c(Cl)cccc1Cl>>O=C(O)c1cc2c(Cl)cccc2s1 -US05204462,6,O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)CCCCc1ccccc1>>O=C(O)[C@@H]1CCCN1C(=O)CCCCc1ccccc1 -US07498350B2,3,CC1(C)OB(c2ccc(N3C[C@H](Cn4cc(Cl)nn4)OC3=O)cc2F)OC1(C)C.Cn1nnc(-c2ccc(Br)cn2)n1>>Cn1nnc(-c2ccc(-c3ccc(N4C[C@H](Cn5cc(Cl)nn5)OC4=O)cc3F)cn2)n1 -US20140235533A1,3,C=C[Mg+].O=C(c1cc(Cl)c(Cl)c(Cl)c1)C(F)(F)F>>C=CC(O)(c1cc(Cl)c(Cl)c(Cl)c1)C(F)(F)F -US06288082B1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Cc1nc2cc(N)ccc2s1>>COc1cc2ncc(C#N)c(Nc3ccc4sc(C)nc4c3)c2cc1OC -US08309581B2,1,BrCc1ccccc1.Fc1cc2nc(-c3cccnc3Cl)[nH]c2cc1F>>Fc1cc2nc(-c3cccnc3Cl)n(Cc3ccccc3)c2cc1F -US20150080549A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSSC(CN=[N+]=[N-])C[C@H](N)C(=O)O>>CSSC(CN=[N+]=[N-])C[C@H](NC(=O)OC(C)(C)C)C(=O)O -US20110130453A1,2,CCOC(=O)Cc1ccc(OC)c(Oc2ccc(N)cc2CN(CC)C(=O)C2CC2)c1.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(NC(=O)c3ccc(Cl)cc3)cc2CN(CC)C(=O)C2CC2)c1 -US04101546,1,ClCSc1nc(Cl)c(Cl)nc1Cl.N#C[S-]>>N#CSCSc1nc(Cl)c(Cl)nc1Cl -US07989442B2,5,N[C@@H]1CCCN2c3cc(Br)c(F)cc3Oc3ccccc3[C@@H]12.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(N[C@@H]1CCCN2c3cc(Br)c(F)cc3Oc3ccccc3[C@@H]12)C(F)(F)F -US09029399B2,1,Clc1cc(I)ccn1.O=C1NCCN1c1cnccc1C1CC1>>O=C1N(c2ccnc(Cl)c2)CCN1c1cnccc1C1CC1 -US20080139530A1,1,CC1(c2ccsc2)OCC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21.CI>>Cn1c(C#N)ccc1-c1ccc2c(c1)C(C)(c1ccsc1)OCC(=O)N2 -US06734193B1,7,CCOC(=O)/C(F)=C(/CC)c1cc(C(C)C)cc2c1N(CC)CCC2(C)C>>CC/C(=C(\F)CO)c1cc(C(C)C)cc2c1N(CC)CCC2(C)C -US20060069149A1,1,CN(C)CCCCl.Oc1ccc2c(c1)Oc1ccccc1-c1ccsc1-2>>CN(C)CCCOc1ccc2c(c1)Oc1ccccc1-c1ccsc1-2 -US20020120145A1,1,Cn1cncc1C(O)(c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C)c1ccc(Cl)cn1.NC1CC1>>Cn1cncc1C(NC1CC1)(c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C)c1ccc(Cl)cn1 -US05807885,2,NCc1ccc([N+](=O)[O-])cc1.O=C(Cl)N(c1ccccc1)c1ccccc1>>O=C(NCc1ccc([N+](=O)[O-])cc1)N(c1ccccc1)c1ccccc1 -US06136821,3,O=C(O)c1ccc(-c2cc3cccnc3c(Br)n2)cc1.OB(O)c1cccc2nonc12>>O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc4nonc34)n2)cc1 -US05753679,7,O=C(OC1CCN(Cc2ccc([N+](=O)[O-])cc2)CC1)c1ccccc1>>Nc1ccc(CN2CCC(OC(=O)c3ccccc3)CC2)cc1 -US04876149,7,C=COC(C)=O>>C=CO -US05436369,6,CCOC(=O)c1cccc(/C(=C/CCc2ccc(C(C)(C)C)c(C34CC5CC(CC(C5)C3)C4)c2O[SiH](C)C)CO[Si](C)(C)C(C)(C)C)c1>>CCOC(=O)c1cccc(/C(=C/CCc2ccc(C(C)(C)C)c(C34CC5CC(CC(C5)C3)C4)c2O[SiH](C)C)CO)c1 -US06492416B1,3,CSc1ccccc1F.O=C(Cl)Cc1ccccc1>>CSc1ccc(C(=O)Cc2ccccc2)cc1F -US06348474B1,7,COC(=O)c1ccc2sc(C)c(C(=O)c3ccc(Cl)cc3Cl)c2c1>>COC(=O)c1ccc2sc(C)c(C(O)c3ccc(Cl)cc3Cl)c2c1 -US08735584B2,1,Nc1cccc(OCc2ccccc2)c1.O=c1[nH]c2nccc(Cl)c2c2ccccc12>>O=c1[nH]c2nccc(Nc3cccc(OCc4ccccc4)c3)c2c2ccccc12 -US20100168062A1,6,Cc1c(-c2cnc3cccc(-c4cc(F)c(CN5CCOCC5)c(F)c4)c3n2)cnn1C1CCN(C(=O)OC(C)(C)C)CC1>>Cc1c(-c2cnc3cccc(-c4cc(F)c(CN5CCOCC5)c(F)c4)c3n2)cnn1C1CCNCC1 -US20150119362A1,1,Clc1cccc(-c2cc(Cl)c3c(n2)CCC3)c1.Nc1ccc(CCCO)cc1>>OCCCc1ccc(Nc2cc(-c3cccc(Cl)c3)nc3c2CCC3)cc1 -US20090192162A1,6,CCOC(=O)COc1ccc(Sc2cc(C#CCN3CCOCC3)cc(OCCc3ccc(Cl)cc3)c2)cc1C>>Cc1cc(Sc2cc(C#CCN3CCOCC3)cc(OCCc3ccc(Cl)cc3)c2)ccc1OCC(=O)O -US20150159142A1,1,CC(C)Br.O=C(C=Cc1c[nH]c2ccccc12)Nc1cccc(C(=O)O)c1>>CC(C)OC(=O)c1cccc(NC(=O)C=Cc2c[nH]c3ccccc23)c1 -US06268365B1,1,COC1CCC(CBr)CC1.Cc1cc[nH]c(=O)c1[N+](=O)[O-]>>CO[C@@H]1CC[C@H](Cn2ccc(C)c([N+](=O)[O-])c2=O)CC1 -US06552054B1,6,COc1cc(C)cc2oc(C(=O)O)cc(=O)c12>>Cc1cc(O)c2c(=O)cc(C(=O)O)oc2c1 -US20050250797A1,1,COCC#Cc1cc(Br)c(N)c2c1OCO2.COc1cc2c(Cl)ncnc2cc1OCCCN1CCOCC1>>COCC#Cc1cc(Br)c(Nc2ncnc3cc(OCCCN4CCOCC4)c(OC)cc23)c2c1OCO2 -US06075145,7,O=C1CN2CCC1CC2>>OC1CN2CCC1CC2 -US20100234219A1,6,COC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12>>O=C(O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12 -US08399465B2,6,CC(=O)N(C1CC1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)N(C1CCNCC1)C1CC1 -US20150152096A1,7,C[C@H]1OCC(=O)N(Cc2ccccc2)[C@@H]1C(=O)OCc1ccccc1>>C[C@H]1OCCN(Cc2ccccc2)[C@@H]1C(=O)OCc1ccccc1 -US20090221555A1,1,COCCN.COc1cc2c(cc1[N+](=O)[O-])CCC(=O)CC2>>COCCNC1CCc2cc(OC)c([N+](=O)[O-])cc2CC1 -US08026273B2,8,CCOC(=O)CC[C@H](CO)NC(=O)OC(C)(C)C>>CCOC(=O)CC[C@H](C=O)NC(=O)OC(C)(C)C -US05929085,1,C=O.CCC1Cc2ccc([N+](=O)[O-])cc2CN1>>CCC1Cc2ccc([N+](=O)[O-])cc2CN1C -US20040019023A1,7,CC(=O)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](O)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C -US06806365B2,6,CCOC(=O)C1(Cc2ccccc2)CCCC1>>O=C(O)C1(Cc2ccccc2)CCCC1 -US09073929B2,2,CNC.Cc1nnc2n1-c1ccc(-c3cncc(C(C)(C)C(=O)O)c3)cc1CC2>>Cc1nnc2n1-c1ccc(-c3cncc(C(C)(C)C(=O)N(C)C)c3)cc1CC2 -US07772253B2,2,CCOc1cc(CN2CCC(N)CC2)ccc1Cl.COc1cccc(C(=O)O)c1OC>>CCOc1cc(CN2CCC(NC(=O)c3cccc(OC)c3OC)CC2)ccc1Cl -US20100099695A1,2,CC(C)(C)[C@@H]1NC(=O)OCCCCCC=Cc2cccnc2O[C@@H]2C[C@@H](C(=O)O)N(C2)C1=O.CC[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)C1CC1>>CC[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)OCCCCCC=Cc1cccnc1O2)C(=O)NS(=O)(=O)C1CC1 -US07381728B2,1,C[C@H]1CNC[C@@H](C)N1.N#Cc1ccc(Cl)cc1[N+](=O)[O-]>>C[C@H]1CN(c2ccc(C#N)c([N+](=O)[O-])c2)C[C@@H](C)N1 -US20050065135A1,1,C1CCNC1.C=C[C@@]12CCc3cc(O)ccc3[C@H]1[C@@H](CCCCCCCl)C[C@@]1(C)[C@H]2CC[C@@H]1O>>C=C[C@@]12CCc3cc(O)ccc3[C@H]1[C@@H](CCCCCCN1CCCC1)C[C@@]1(C)[C@H]2CC[C@@H]1O -US05854268,1,COC(CCCCBr)OC.c1ccc(CNCC2CCNCC2)cc1>>COC(CCCCN1CCC(CNCc2ccccc2)CC1)OC -US06057311,2,CC(=O)N1[C@H](CC23CC4CC(CC(C4)C2)C3)C(=O)N(Cc2ccccc2)c2ccccc2C(=O)C[C@H]1C(=O)[O-].NCC(=O)OCc1ccccc1>>CC(=O)N1[C@H](CC23CC4CC(CC(C4)C2)C3)C(=O)N(Cc2ccccc2)c2ccccc2C(=O)C[C@H]1C(=O)NCC(=O)OCc1ccccc1 -US20130158075A1,6,CC(C)(C)OC(=O)C(C)(C)N1CCC(c2ncc(-c3ccc(NC(=O)Nc4c(F)cc(F)cc4F)cc3)s2)CC1>>CC(C)(C(=O)O)N1CCC(c2ncc(-c3ccc(NC(=O)Nc4c(F)cc(F)cc4F)cc3)s2)CC1 -US20050203087A1,2,COC(=O)COc1c(C(=O)Cl)sc(Br)c1Br.Nc1nccs1>>COC(=O)COc1c(C(=O)Nc2nccs2)sc(Br)c1Br -US20020183335A1,1,C1CCNC1.O=C(NCc1ccc(C(F)(F)F)cc1)c1cnc(Cl)nc1Cl>>O=C(NCc1ccc(C(F)(F)F)cc1)c1cnc(Cl)nc1N1CCCC1 -US20130289033A1,3,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(I)cc1.OB(O)c1ccc(F)cc1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(-c2ccc(F)cc2)cc1 -US20140213581A1,1,C[C@H](O)C[C@H]1[C@@](C)(c2cc([N+](=O)[O-])ccc2F)N=C(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(C)(C)S1(=O)=O>>C[C@H]1C[C@@H]2[C@](C)(N=C(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(C)(C)S2(=O)=O)c2cc([N+](=O)[O-])ccc2O1 -US07452908B2,2,CC(=O)OC(C)=O.N[C@H]1C[C@@H](C(=O)N2CCC[C@@H]2C(=O)NC[C@H]2CCCN(CC3CCCCC3)C2)N(C(=O)CC(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>CC(=O)N[C@H]1C[C@@H](C(=O)N2CCC[C@@H]2C(=O)NC[C@H]2CCCN(CC3CCCCC3)C2)N(C(=O)CC(c2ccccc2)(c2ccccc2)c2ccccc2)C1 -US06437139B1,1,C[O-].Cc1cc(Cl)cc(C)n1>>COc1cc(C)nc(C)c1 -US20150119373A1,6,C=C(C)[C@@H]1CC[C@]2(c3nnc(-c4cccnc4)o3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(c3nnc(-c4cccnc4)o3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US05607947,1,C1CCN(C2CCNCC2)CC1.COc1ccc(C(=O)N2CC[C@](CCOS(C)(=O)=O)(c3ccc(Cl)c(Cl)c3)C2)c(OC)c1>>COc1ccc(C(=O)N2CC[C@@](CCN3CCC(N4CCCCC4)CC3)(c3ccc(Cl)c(Cl)c3)C2)c(OC)c1 -USRE039679E1,1,O=C(CCCCl)c1ccc(F)cc1.c1cc2c3c(c1)C1CCNCCC1N3CCO2>>O=C(CCCN1CCC2c3cccc4c3N(CCO4)C2CC1)c1ccc(F)cc1 -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)Cc4cccnc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cc1[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc2c1C(=O)O>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](Cc4cccnc4)NC(=O)c4c(C)[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US20070135367A1,7,O=[N+]([O-])c1ccccc1N1CCCCC1>>Nc1ccccc1N1CCCCC1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CSc4nncn4C)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CS(=O)c4nncn4C)cc2)CCN3CC(C)C)cc1 -US06043247,1,C1CNCCN1.Clc1ccc2ccccc2n1>>c1ccc2nc(N3CCNCC3)ccc2c1 -US20090247519A1,2,CC[C@H](CO)NC(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC[C@H](COS(C)(=O)=O)NC(=O)OC(C)(C)C -US08680108B2,6,CCN(CC)/N=N/c1c(C#C[Si](C)(C)C)c(F)cc(C(C)=O)c1-c1cccc(F)c1>>C#Cc1c(F)cc(C(C)=O)c(-c2cccc(F)c2)c1/N=N/N(CC)CC -US20080318945A1,2,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O.CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCNCC1>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(C(=O)[C@H](CO)NC(=O)OC(C)(C)C)CC1 -US20150274738A1,7,CC(=O)N1CCN(C2CCC(n3nc(-c4ccc(Oc5ccccc5)c([N+](=O)[O-])c4)c4c(NC(=O)OC(C)(C)C)ncnc43)CC2)CC1>>CC(=O)N1CCN(C2CCC(n3nc(-c4ccc(Oc5ccccc5)c(N)c4)c4c(NC(=O)OC(C)(C)C)ncnc43)CC2)CC1 -US08178668B2,1,Brc1cnc(Br)s1.CN1CCNCC1>>CN1CCN(c2ncc(Br)s2)CC1 -US05254755,10,CC(F)(F)C(F)(F)C(=CF)C(F)(F)F.O>>CC(F)(F)C(F)(F)C(O)(CF)C(F)(F)F -US20110319445A1,2,CCNCc1nc2ccccc2cc1-c1cc(CC(=O)OCC)ccc1OC.O=C(Cl)C1CC1>>CCOC(=O)Cc1ccc(OC)c(-c2cc3ccccc3nc2CN(CC)C(=O)C2CC2)c1 -US20150231143A1,3,CCC(=O)c1[nH]c(-c2ccc(Cl)cc2)c(C)c1Br.NS(=O)(=O)c1ccc(B(O)O)cc1>>CCC(=O)c1[nH]c(-c2ccc(Cl)cc2)c(C)c1-c1ccc(S(N)(=O)=O)cc1 -US20070088044A1,1,CC(C)N1CC(O)C1.Fc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl>>CC(C)N1CC(Oc2cccc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1 -US08148380B2,2,CCOC(=O)C(=O)c1csc(N)n1.O=C=NCc1cccc(F)c1>>CCOC(=O)C(=O)c1csc(NC(=O)NCc2cccc(F)c2)n1 -US20060094778A1,7,CCC(CC)(c1ccc(OCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(C(=O)OC)c(C)c1>>CCC(CC)(c1ccc(CO)c(C)c1)c1ccc(OCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1 -US20090221584A1,2,CCCCCOC(=O)c1cc(N)ncc1Sc1ccc(S(=O)(=O)N2CCCCC2)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>CCCCCOC(=O)c1cc(NS(=O)(=O)c2ccc(Cl)cc2Cl)ncc1Sc1ccc(S(=O)(=O)N2CCCCC2)cc1 -US06548126B1,1,CCCC1CCC(c2ccc(O)cc2)CC1.CCOc1ccc(C(=O)O)c(F)c1F>>CCCC1CCC(c2ccc(OC(=O)c3ccc(OCC)c(F)c3F)cc2)CC1 -US20150225405A1,7,COC(=O)c1c(Br)cnn1COCC[Si](C)(C)C>>C[Si](C)(C)CCOCn1ncc(Br)c1CO -US20020035266A1,6,COC(=O)/C(=C/C1CCCC1)c1ccc(-n2nnnc2C)c(F)c1>>Cc1nnnn1-c1ccc(/C(=C\C2CCCC2)C(=O)O)cc1F -US06407094B1,7,CC(C)(C)OCCOc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C#Cc1ccc(F)cc1>>CC(C)(C)OCCOc1cc(NC(=O)OC(C)(C)C)c(N)cc1C#Cc1ccc(F)cc1 -US20050222424A1,6,CCOC(=O)C(C)(C)Oc1ccc(CN(Cc2ccccc2OC)c2cc(-c3ccc(C(F)(F)F)cc3)nn2C)cc1C>>COc1ccccc1CN(Cc1ccc(OC(C)(C)C(=O)O)c(C)c1)c1cc(-c2ccc(C(F)(F)F)cc2)nn1C -US20060199836A1,9,CCCCOC(=O)c1nc(Br)c2cc(-c3ccc(Oc4ccccc4)cc3)sc2c1O>>CCCCOC(=O)c1ncc2cc(-c3ccc(Oc4ccccc4)cc3)sc2c1O -US06376426B1,1,CI.O=c1cc(C(F)(F)F)[nH]c(=O)n1-n1ccc2c(Cl)cccc21>>Cn1c(C(F)(F)F)cc(=O)n(-n2ccc3c(Cl)cccc32)c1=O -US20120065202A1,3,CC1(C)OB(c2ccc(NC(N)=O)cc2)OC1(C)C.C[C@H]1COCCN1c1nc(Cl)nc2c1CN(C)C2>>C[C@H]1COCCN1c1nc(-c2ccc(NC(N)=O)cc2)nc2c1CN(C)C2 -US06867218B2,3,CCOC(=O)/C=C(\C)c1ccc(Br)cc1.COc1ccc(Cl)cc1B(O)O>>CCOC(=O)/C=C(\C)c1ccc(-c2cc(Cl)ccc2OC)cc1 -US09040522B2,2,CNCC1CCN(C(C)C)C1.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)N(C)CC3CCN(C(C)C)C3)cn2)c1O -US20120136151A1,1,CC(C)(Cc1ccccc1)OC(=O)C[C@H]1C[C@@H](CCl)OC(C)(C)O1.[S-]c1nnnn1-c1ccccc1>>CC(C)(Cc1ccccc1)OC(=O)C[C@H]1C[C@@H](CSc2nnnn2-c2ccccc2)OC(C)(C)O1 -US20150025070A1,2,CC[C@H](C)CNCc1nc2c(c(=O)[nH]1)COCC2.O=C(O)CN1CCC(C(=O)c2ccc(F)cc2)CC1>>CC[C@H](C)CN(Cc1nc2c(c(=O)[nH]1)COCC2)C(=O)CN1CCC(C(=O)c2ccc(F)cc2)CC1 -US09062013B2,2,Cc1cccc([C@H]2[C@H](C(=O)O)C2(C)C)c1.Nc1ccc(F)c(F)c1>>Cc1cccc([C@H]2[C@H](C(=O)Nc3ccc(F)c(F)c3)C2(C)C)c1 -US06818644B1,1,FC(F)(F)c1cccc(N2CCNCC2)c1.O=C(NCC(F)(F)F)C1(CCCCBr)c2ccccc2-c2ccccc21>>O=C(NCC(F)(F)F)C1(CCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)c2ccccc2-c2ccccc21 -US05080710,1,BrCC1CCOCC1.Nc1ccc2c(c1)NC(=O)CO2>>Nc1ccc2c(c1)N(CC1CCOCC1)C(=O)CO2 -US20070232615A1,1,CC(C)N(Cc1cn2c(F)cccc2n1)C1CCCc2cccnc21.CN1CCNCC1>>CC(C)N(Cc1cn2c(N3CCN(C)CC3)cccc2n1)C1CCCc2cccnc21 -US20080161289A1,2,CN.COC(=O)c1cnc(-c2nc3c(s2)CCN(C2CCC2)CC3)cn1>>CNC(=O)c1cnc(-c2nc3c(s2)CCN(C2CCC2)CC3)cn1 -US05861401,2,Nc1ccc(Cl)nn1.O=S(=O)(Cl)c1ccccc1-c1ccccc1>>O=S(=O)(Nc1ccc(Cl)nn1)c1ccccc1-c1ccccc1 -US07452886B2,1,CC(C)(C)Cn1c(CBr)cc2cnc(C#N)nc21.Oc1ccc(Cl)nc1>>CC(C)(C)Cn1c(COc2ccc(Cl)nc2)cc2cnc(C#N)nc21 -US08097758B2,2,CC(C)O.O=C(O)C=Cc1ccco1>>CC(C)OC(=O)/C=C/c1ccco1 -US20090156642A1,3,CCCC[Sn](CCCC)(CCCC)c1ccnn1C.CN(Cc1cc(Br)c(S(=O)(=O)c2ccccc2)s1)C(=O)OC(C)(C)C>>CN(Cc1cc(-c2ccnn2C)c(S(=O)(=O)c2ccccc2)s1)C(=O)OC(C)(C)C -US06465513B1,3,C#CCC(NC(=O)C12CC3CC(C1)CC(C(=O)OC)(C3)C2)C(=O)OC(C)(C)C.CN(C)C(=O)Cl>>COC(=O)C12CC3CC(CC(C(=O)NC(CC#CC(=O)N(C)C)C(=O)OC(C)(C)C)(C3)C1)C2 -US20100113435A1,2,CCOC(=O)Cc1csc(N)n1.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1Cl>>CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2Cl)n1 -US20100120860A1,1,N#Cc1nnc(NC2CCNCC2)s1.O=Cc1cccc(C(F)(F)F)c1>>N#Cc1nnc(NC2CCN(Cc3cccc(C(F)(F)F)c3)CC2)s1 -US20150168829A1,2,CC(C)(C)OC(=O)C1C2CC3C(OC(=O)C31)C2O.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>CC(C)(C)OC(=O)C1C2CC3C(OC(=O)C31)C2OC(=O)C12CC3CC(CC(C3)C1)C2 -US07932281B2,1,CCCN(CCC)CCCCNCc1ccc(CNC(=O)OC(C)(C)C)cc1.N#CCBr>>CCCN(CCC)CCCCN(CC#N)Cc1ccc(CNC(=O)OC(C)(C)C)cc1 -US20070197559A1,1,CC(C)(C)c1ccc(N)cc1.Clc1ccccc1-n1ncc2c(Cl)ncnc21>>CC(C)(C)c1ccc(Nc2ncnc3c2cnn3-c2ccccc2Cl)cc1 -US05646173,4,C[C@@H](O)CN.O=CCC1Cc2ccc(Br)cc2C1=O>>C[C@@H](O)Cn1ccc2c1-c1cc(Br)ccc1C2 -US08785655B2,2,COC(=O)[C@H](O)c1ccccc1.O=C(Br)CBr>>COC(=O)[C@H](OC(=O)CBr)c1ccccc1 -US20090074738A1,1,CC(C)(C)OC(=O)NCCO.O=Cc1ccc(O)cc1>>CC(C)(C)OC(=O)NCCOc1ccc(C=O)cc1 -US20120309997A1,7,COC(=O)/C=C(\C)NC(C)=O>>COC(=O)C[C@H](C)NC(C)=O -US08093265B2,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1ccc2c(=O)n([C@H](C)COS(C)(=O)=O)ccc2c1NC(=O)Cc1ccc(C(F)(F)F)c(F)c1>>Cc1ccc2c(=O)n([C@H](C)CN3CCN(C(=O)OC(C)(C)C)CC3)ccc2c1NC(=O)Cc1ccc(C(F)(F)F)c(F)c1 -US20110275797A1,1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(C2CCNCC2)ccc1O.CC=O>>CCN1CCC(c2ccc(O)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)OC(C)(C)C)c2)CC1 -US20090124596A1,2,N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccccc4CN4CCOCC4)c3)c2=O)CC1.O=C(O)C1(O)CC1>>O=C(N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccccc4CN4CCOCC4)c3)c2=O)CC1)C1(O)CC1 -US05055223,7,CCCCCC1CC=C(c2ccc(S(F)(F)(F)(F)F)cc2)CC1>>CCCCC[C@@H]1CC[C@@H](c2ccc(S(F)(F)(F)(F)F)cc2)CC1 -US07999107B2,2,CC(C)(C)C(=O)Cl.CC1(C)CC(N)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Br)cc3Cl)nc2O1>>CC1(C)CC(NC(=O)C(C)(C)C)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Br)cc3Cl)nc2O1 -US20140094474A1,2,CCOC(=O)c1coc(C(C)(C)O)n1.C[C@H](CN)n1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1>>C[C@H](CNC(=O)c1coc(C(C)(C)O)n1)n1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1 -US08088930B2,1,Cc1cc(C#N)cc(C)c1O.OCC(C1CCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21>>Cc1cc(C#N)cc(C)c1OCC(C1CCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21 -US07662830B2,1,CC(C)(C)OC(=O)N1CCN(c2cc(-c3ccc(F)c(Cl)c3)nc(Cl)n2)CC1.CCCN1CCNCC1>>CCCN1CCN(c2nc(-c3ccc(F)c(Cl)c3)cc(N3CCN(C(=O)OC(C)(C)C)CC3)n2)CC1 -US06531471B2,2,CC1(C)OCC(=O)NC1c1ccc(F)c(F)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC1(C)OCC(=O)N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1c1ccc(F)c(F)c1 -US08686022B2,6,COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)OC(C)(C)C)CC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)c2cc3cccc(CN4CCNCC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O -US08952169B2,6,CC1(C)CCCC(COc2cc(F)c(C(=O)OC(C)(C)C)cc2C2CC2)C1>>CC1(C)CCCC(COc2cc(F)c(C(=O)O)cc2C2CC2)C1 -US20030096809A1,1,CC(C)(C)OC(=O)NC1CNc2ccccc2NC1=O.O=C1CCCCC1>>CC(C)(C)OC(=O)N[C@@H]1CN(C2CCCCC2)c2ccccc2NC1=O -US04670604,6,COC(=O)C(=O)Nc1cccc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC(F)(F)F)c1>>COC(=O)C(=O)Nc1cccc(OCCCOc2ccc(C(C)=O)c(O)c2CCC(F)(F)F)c1 -US20090111862A1,1,Fc1cc(CCl)ccc1OCc1ccccc1.N#Cc1ccc(Nn2cnnc2)cc1>>N#Cc1ccc(N(Cc2ccc(OCc3ccccc3)c(F)c2)n2cnnc2)cc1 -US20080255134A1,6,Cc1[nH]c(=O)c(C#N)cc1-c1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1>>Cc1[nH]c(=O)c(C#N)cc1-c1ccc(OCCCN)cc1 -US20100069629A1,1,COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4)cn2)cc1.Cc1cc(C(=O)N(C)CCN2CCOCC2)ccc1Br>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccc(C(=O)N(C)CCN4CCOCC4)cc3C)cn2)cc1 -US20090274650A1,1,CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(O)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCCO2.N#Cc1cccc(CCl)c1>>CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(OCc2cccc(C#N)c2)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCCO2 -US08697883B2,2,CNC(=O)c1cc(CO)on1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CNC(=O)c1cc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)on1 -US20100069629A1,2,CCN1CCNCC1.COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccc(C(=O)O)cc3F)cn2)cc1>>CCN1CCN(C(=O)c2ccc(N3CCc4c(-c5cnc(N(Cc6ccc(OC)cc6)Cc6ccc(OC)cc6)nc5)nc(N5CCOCC5)nc43)c(F)c2)CC1 -US04572913,1,NC1=NN(c2ccc(Br)c(C(F)(F)F)c2)CC1.O=Cc1ccccc1O>>Oc1ccccc1C=NC1=NN(c2ccc(Br)c(C(F)(F)F)c2)CC1 -US06204415B1,1,CCSC(F)(F)C(O)(Cn1cncn1)c1ccc(F)cc1F.CI>>CCSC(F)(F)C(Cn1cncn1)(OC)c1ccc(F)cc1F -US06462035B1,6,CCOc1ccc2c(c1)CC1CC2CN(Cc2ccccc2)C1>>CCOc1ccc2c(c1)CC1CNCC2C1 -US20070027163A1,2,CC(=O)Cl.NCCn1cc(C(=O)N2CCN(c3ccccc3F)CC2)c2ccc(Cl)cc21>>CC(=O)NCCn1cc(C(=O)N2CCN(c3ccccc3F)CC2)c2ccc(Cl)cc21 -US20140329863A1,4,Cc1ccnc(NC(N)=S)c1.O=C(CBr)c1cc(-c2ccc(Cl)cc2)no1>>Cc1ccnc(Nc2nc(-c3cc(-c4ccc(Cl)cc4)no3)cs2)c1 -US03946018,2,CC1(C)C(=O)NC(c2ccc(N)cc2)c2ccccc21.O=C(Cl)CCl>>CC1(C)C(=O)NC(c2ccc(NC(=O)CCl)cc2)c2ccccc21 -US20040198608A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1nc(Cl)c(F)c(N)c1Cl>>C=Cc1nc(C(=O)OC)c(Cl)c(N)c1F -US07781445B2,7,COc1ccc(OC)c(C=NCC(OC)OC)c1>>COc1ccc(OC)c(CNCC(OC)OC)c1 -US08080566B1,7,CCn1c2ccccc2c2cccc(C(=O)OC)c21>>CCn1c2ccccc2c2cccc(CO)c21 -US20060173004A1,2,CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)O.C[C@H]1CN[C@H](COCc2ccccc2)CN1Cc1ccc(F)cc1>>CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1COCc1ccccc1 -US20140343049A1,3,C=C[Mg+].O=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F>>C=CC(O)(c1cc(Cl)cc(Cl)c1)C(F)(F)F -US20050148606A1,1,Cn1c(=O)c2[nH]c(Cl)nc2n(C)c1=O.N#Cc1ccccc1CBr>>Cn1c(=O)c2c(nc(Cl)n2Cc2ccccc2C#N)n(C)c1=O -US20140357641A1,1,C=CCCCC=O.Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)NCCC3)cc1>>C=CCCCCN1CCCc2nc(-c3ccc(C)cc3)c(-c3ccc(C)cc3)nc21 -US06107329,2,NC(Cc1cccc(C(F)(F)F)c1)C(=O)N1CCSC1.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>O=C(NC(Cc1cccc(C(F)(F)F)c1)C(=O)N1CCSC1)c1cc2cc(Cl)ccc2[nH]1 -US04430339,4,C=C(CCCCCCCC1CCCCC1)C(=O)OCC.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)C1(CCCCCCCC2CCCCC2)CO1 -US07872028B2,1,CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@H](O)CCl>>CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@H]1CO1 -US20040192676A1,1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)C1CCCCC1=O>>CCOC(=O)[C@H]1CCCC[C@H]1N1CCN(C(=O)OC(C)(C)C)CC1 -US20110190278A1,2,CC(C)N(C(=O)c1cc2c(cc1C(F)(F)F)OC(C)(C)C(=O)N2CCNC(=O)C(F)F)[C@@H]1CC[C@H](CCNC2CC2)N(C(=O)OC(C)(C)C)C1.O=C(O)Cc1ccc(Cl)cc1>>CC(C)N(C(=O)c1cc2c(cc1C(F)(F)F)OC(C)(C)C(=O)N2CCNC(=O)C(F)F)[C@@H]1CC[C@H](CCN(C(=O)Cc2ccc(Cl)cc2)C2CC2)N(C(=O)OC(C)(C)C)C1 -US04686219,7,CCOC(=O)c1nccn1Cc1ccccc1[N+](=O)[O-]>>CCOC(=O)c1nccn1Cc1ccccc1N -US07034015B2,2,Cc1ccccc1C(=O)c1ccc(Nc2ccccc2NC(=O)CCC(=O)O)cc1Cl.NCC(O)CO>>Cc1ccccc1C(=O)c1ccc(Nc2ccccc2NC(=O)CCC(=O)NCC(O)CO)cc1Cl -US08957068B2,6,CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(CN3CCN(C(=O)OCc4ccccc4)CC3)cc2)n1>>CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(CN3CCNCC3)cc2)n1 -US09120749B2,3,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](n2cc(Nc3c(C(=O)C4CC4)cnc4ccc(Br)cc34)cn2)CC1.CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](n2cc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(Cl)c(O)c(Cl)c5)cc34)cn2)CC1 -US05872115,7,CCCCCCCNC(=O)Nc1ccccc1C(=O)Nc1cccnc1>>CCCCCCCNC(=O)Nc1ccccc1C(=O)NC1CCCNC1 -US07393865B2,3,COc1cccc(C(=O)c2c(CCN(C)C)sc3ccccc23)n1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(c1cccc(OC)n1)c1c(CCN(C)C)sc2ccccc12 -US20110130380A1,9,Fc1cccc(CNc2cccc(-c3cc(F)ncc3Cl)n2)c1.[NH4+]>>Nc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1 -US20090035698A1,1,C=C(C)C(=O)O.ClCOC1C2CC3CC(C2)CC1C3>>C=C(C)C(=O)OCOC1C2CC3CC(C2)CC1C3 -US20120289522A1,2,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CN)cc3)cc2)CC1.O=C(Cl)Cc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CNC(=O)Cc4ccccc4)cc3)cc2)CC1 -US20040232383A1,6,C=CC(=O)OCCCCCCOc1ccc(C(=O)Oc2ccc(C(=O)O[C@@H]3COC4C3OC[C@@H]4OC3CCCCO3)cc2)cc1>>C=CC(=O)OCCCCCCOc1ccc(C(=O)Oc2ccc(C(=O)O[C@@H]3COC4C3OC[C@@H]4O)cc2)cc1 -US20060004043A1,2,CCOC(=O)CNC(C)(C)C.NN>>CC(C)(C)NCC(=O)NN -US05414132,2,NCc1ccccc1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=S(=O)(NCc1ccccc1)c1ccc(Br)cc1 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.O=C(O)c1cnccn1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)c4cnccn4)nc3cc21 -US20120088750A1,1,C=CCC1(C(=O)OCC)CCNCC1.Clc1ncc(Br)cn1>>C=CCC1(C(=O)OCC)CCN(c2ncc(Br)cn2)CC1 -US06201087B1,10,Cc1ccc2ccc(=O)oc2c1.O=C1CCC(=O)N1Br>>O=c1ccc2ccc(CBr)cc2o1 -US20130203815A1,7,CCOC(=O)C1C(=O)N(C)CC1c1c(OC)cc(OC)cc1OC>>COc1cc(OC)c(C2CN(C)C(=O)C2CO)c(OC)c1 -US20090143354A1,1,CN.CS(=O)(=O)O[C@@H]1CCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)C1>>CN[C@H]1CCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)C1 -US07309720B2,3,C=C[Sn](CCCC)(CCCC)CCCC.CCOC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)OCC>>C=Cc1ccc(C[C@H](OCC)C(=O)OCC)cc1 -US20150051395A1,3,Brc1ccc(Br)nc1.COC(=O)[C@H](CI)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(Br)cn1)NC(=O)OC(C)(C)C -US20050159402A1,2,Nc1ccc(C2CCN(Cc3ccccc3)CC2)cc1.O=C(O)c1ccccc1-c1ccccc1>>O=C(Nc1ccc(C2CCN(Cc3ccccc3)CC2)cc1)c1ccccc1-c1ccccc1 -US20070197604A1,3,CCS(=O)(=O)c1ccc(B(O)O)cc1.Cc1oc(-c2ccc(Br)cc2)nc1CCN1CCCC1>>CCS(=O)(=O)c1ccc(-c2ccc(-c3nc(CCN4CCCC4)c(C)o3)cc2)cc1 -US20150057279A1,2,NCCNc1noc(C2CC2)n1.O=C(O)/C=C/C(F)(F)F>>O=C(/C=C/C(F)(F)F)NCCNc1noc(C2CC2)n1 -US05554706,1,N#Cc1ccc(-c2ccc(O)cc2)cc1.OCCCCCCBr>>N#Cc1ccc(-c2ccc(OCCCCCCO)cc2)cc1 -US20140155391A1,6,COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1N(C(=O)OC(C)(C)C)S(=O)(=O)CCN1CCN(C)CC1>>COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NS(=O)(=O)CCN1CCN(C)CC1 -US20140213586A1,6,COCOCCn1cc(C(=O)C(Nc2cc(OC)cc(OC)c2)c2ccccc2)c2ccccc21>>COc1cc(NC(C(=O)c2cn(CCO)c3ccccc23)c2ccccc2)cc(OC)c1 -US07745443B2,2,Cc1cc(N)c2cc(C(=O)Nc3ccc(CN)cc3)ccc2n1.O=C(O)c1ccnc(Cl)c1>>Cc1cc(N)c2cc(C(=O)Nc3ccc(CNC(=O)c4ccnc(Cl)c4)cc3)ccc2n1 -US20100113421A1,6,CCOC(=O)c1[nH]c(C(N)=O)c(S(=O)(=O)c2ccccc2)c1C>>Cc1c(C(=O)O)[nH]c(C(N)=O)c1S(=O)(=O)c1ccccc1 -US08618094B2,6,C[C@H](c1ccccc1)N1C[C@@](CCO[Si](C)(C)C(C)(C)C)(C(=O)OC(C)(C)C)C(F)C1=O>>C[C@H](c1ccccc1)N1C[C@@](CCO)(C(=O)OC(C)(C)C)C(F)C1=O -US05889031,1,CC(C)O.CCCC(=O)NC[C@@H]1C[C@H]1c1cccc(O)c1>>CCCC(=O)NC[C@@H]1C[C@H]1c1cccc(OC(C)C)c1 -US20100004238A1,7,O=[N+]([O-])c1ccc(Oc2cccc3occc23)c(Cl)c1>>Nc1ccc(Oc2cccc3occc23)c(Cl)c1 -US05871954,1,CCO.O=C(O)CCCCCCCCCCBr>>CCOCCCCCCCCCCC(=O)O -US20140249120A1,6,COCO[C@@H]1CC[C@@]2(C)[C@H](C1)[C@H](OC)C[C@H]1[C@@H]3CC[C@H](COCc4ccccc4)[C@@]3(C)CC[C@@H]12>>COCO[C@@H]1CC[C@@]2(C)[C@H](C1)[C@H](OC)C[C@H]1[C@@H]3CC[C@H](CO)[C@@]3(C)CC[C@@H]12 -US20140371176A1,5,CC(C)(C)OC(=O)N1CCC(CN[C@@H]2C[C@H]2c2ccc(I)cc2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccc(I)cc2)CC1 -US05057517,7,CCc1nc(Cl)c([N+](=O)[O-])c(Cl)n1>>CCc1nc(Cl)c(N)c(Cl)n1 -US20120270865A2,6,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(F)cc3c2OC)C2CCCCC2)cc1>>COc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)cc2)C2CCCCC2)oc2ccc(F)cc12 -US20150133451A1,1,Cn1ccc(NC(=O)C[C@@H](CO)NC(=O)OC(C)(C)C)n1>>Cn1ccc(N2C[C@@H](NC(=O)OC(C)(C)C)CC2=O)n1 -US20090137804A1,2,Nc1cc(Nc2cccc(Cl)c2)ncn1.O=C=Nc1ccccc1Cl>>O=C(Nc1cc(Nc2cccc(Cl)c2)ncn1)Nc1ccccc1Cl -US20060229336A1,2,CC(C)C(=O)Cl.Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)CC1>>Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccc(Cl)c(S(=O)(=O)NC(=O)C(C)C)c2)CC1 -US20040176602A1,1,CC(C)=O.Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCNCC5)cc4)ccc23)cc1Cl>>CC(C)N1CCN(Cc2ccc(-c3ccc4c(Nc5ccc(Sc6nccn6C)c(Cl)c5)c(C#N)cnc4c3)cc2)CC1 -US07435815B2,1,CCN.Cc1cccc(C=O)n1>>CCNCc1cccc(C)n1 -US06562964B1,1,CCOC(=O)[C@@H]1CCCCN1.Clc1nc2ccccc2s1>>CCOC(=O)[C@@H]1CCCCN1c1nc2ccccc2s1 -US05910504,1,O=[N+]([O-])c1ccc(F)c(F)c1.c1c[nH]nn1>>O=[N+]([O-])c1ccc(-n2ccnn2)c(F)c1 -US20060264628A1,1,BrCc1ccccc1.Cc1nc2c(s1)-c1nc(N)ncc1CC2>>Cc1nc2c(s1)-c1nc(NCc3ccccc3)ncc1CC2 -US04885297,2,CN1CCNCC1.COC(=O)Cn1c(=O)sc2ncc(Cl)cc21>>CN1CCN(C(=O)Cn2c(=O)sc3ncc(Cl)cc32)CC1 -US20150214487A1,1,CC(C)(C)c1ccc(C(N)=O)cc1.NC=O>>CC(C)(C)c1ccc(C(N)=NC=O)cc1 -US20150175623A1,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.OCCN1CCNCC1>>O=C(N1CCN(CCO)CC1)C(F)(F)F -US20090286778A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cccc(SCCOc2cccc([N+](=O)[O-])c2)c1>>CC(C)(C)OC(=O)Nc1cccc(SCCOc2cccc([N+](=O)[O-])c2)c1 -US20090227592A1,7,CC(=O)Oc1cc(OCc2ccccc2C#N)cc(C(=O)Nc2ccc([N+](=O)[O-])cn2)c1>>N#Cc1ccccc1COc1cc(O)cc(C(=O)Nc2ccc([N+](=O)[O-])cn2)c1 -US20100063286A1,1,CCCc1cc(CCC=O)n(C(C)(C)C)n1.c1ccc(N2CCNCC2)cc1>>CCCc1cc(CCCN2CCN(c3ccccc3)CC2)n(C(C)(C)C)n1 -US20150191476A1,6,c1cc(C2CC2)cc(C2OCCO2)c1>>O=Cc1cccc(C2CC2)c1 -US20130225524A1,1,COc1ncc(-c2ccc3c(Cl)c(C(N)=O)cnc3c2)c(OC)n1.Nc1cc(C(=O)O)cc(C2CCCC2)c1>>COc1ncc(-c2ccc3c(Nc4cc(C(=O)O)cc(C5CCCC5)c4)c(C(N)=O)cnc3c2)c(OC)n1 -US20060035897A1,3,Brc1ccc2cnncc2c1.Cc1ccc(NC(=O)c2ccc(CN3CCOCC3)c(C(F)(F)F)c2)cc1Br>>Cc1ccc(NC(=O)c2ccc(CN3CCOCC3)c(C(F)(F)F)c2)cc1-c1ccc2cnncc2c1 -US04610983,2,CC(=O)Cl.O=C(NCCCO)OCc1ccccc1>>CC(=O)OCCCNC(=O)OCc1ccccc1 -US20150087663A1,2,Nc1ccccc1.O=C(O)c1c(F)cccc1[N+](=O)[O-]>>O=C(Nc1ccccc1)c1c(F)cccc1[N+](=O)[O-] -US04521430,1,COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2O)cc1.O=C(O)c1ccc([N+](=O)[O-])c([N+](=O)[O-])c1>>COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(=O)c2ccc([N+](=O)[O-])c([N+](=O)[O-])c2)cc1 -US20040247523A1,6,CC(C)(C)OC(=O)N1Cc2cc(OCCCCCOc3cc(-c4ccccc4)cc(-c4ccccc4)n3)ccc2CC1C(=O)O>>O=C(O)C1Cc2ccc(OCCCCCOc3cc(-c4ccccc4)cc(-c4ccccc4)n3)cc2CN1 -US20100004459A1,1,CC(C)(C)CN.CCOC(=O)c1cccnc1-c1ccc(F)c(C#N)c1>>CCOC(=O)c1cccnc1-c1ccc(NCC(C)(C)C)c(C#N)c1 -US04021479,7,O=C(O)CCC(=O)c1ccc(-c2ccc(F)cc2)cc1>>O=C(O)CCC(O)c1ccc(-c2ccc(F)cc2)cc1 -US20100080786A1,2,CC(F)(F)C(=O)O.C[C@H](N)[C@H](Oc1ccc2c(cnn2-c2cccc(C(=O)N3CCC[C@@H]3C(N)=O)c2)c1)c1ccccc1>>C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2c(cnn2-c2cccc(C(=O)N3CCC[C@@H]3C(N)=O)c2)c1)c1ccccc1 -US20070129334A1,1,CC(C)(C)CN.CS(=O)(=O)OCCn1c(Sc2nc3cccc(Cl)c3s2)nc2c(N)ncnc21>>CC(C)(C)CNCCn1c(Sc2nc3cccc(Cl)c3s2)nc2c(N)ncnc21 -US20080045562A1,2,CCOC(=O)c1cncc2c(COc3cc(NC(=O)c4cccc(Cl)c4)ccc3C)csc12.NCCO>>Cc1ccc(NC(=O)c2cccc(Cl)c2)cc1OCc1csc2c(C(=O)NCCO)cncc12 -US20090239870A1,2,CN1C(=O)NC(=O)C12Cc1cc3ccc(C(=O)O)nc3cc1C2.Nc1ccccc1>>CN1C(=O)NC(=O)C12Cc1cc3ccc(C(=O)Nc4ccccc4)nc3cc1C2 -US08703763B2,3,Nc1nc2c(Br)cccn2n1.OB(O)c1ccc(F)c(F)c1>>Nc1nc2c(-c3ccc(F)c(F)c3)cccn2n1 -US20090105266A1,1,COC(=O)c1cnc(Cl)c(Cl)c1.Cc1ccc(N)cn1>>COC(=O)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 -US20120071471A1,1,CC1(C)OC(=O)Nc2ccc(Br)cc21.NC(=O)CBr>>CC1(C)OC(=O)N(CC(N)=O)c2ccc(Br)cc21 -US20100063299A1,1,CCCCC1=NC2(CCCC2)C(=O)N1.N#Cc1ccccc1-c1ccc(CBr)cc1>>CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2C#N)cc1 -US06825354B2,1,CC#CCBr.CCOC(=O)C(Sc1ccc(O)cc1)c1ccc(Cl)cc1>>CC#CCOc1ccc(SC(C(=O)OCC)c2ccc(Cl)cc2)cc1 -US20050272763A1,6,CC(=O)OCC(=O)Nc1c(C(=O)C(C)(C)O)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12>>CC(C)(O)C(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)CO -US06150359,7,CCn1c(=O)ccc2cnc(Nc3ccccc3)cc21>>CCN1C(=O)CCc2cnc(Nc3ccccc3)cc21 -US06069156,6,COC(=O)CCCc1cc2ccc(C(=O)OC)cc2n1C(C)=O>>COC(=O)CCCc1cc2ccc(C(=O)OC)cc2[nH]1 -US20040152741A1,2,COc1ccc([N+](=O)[O-])cc1N=C=O.NC(C(=O)Nc1ccc(Br)cc1)c1ccccc1>>COc1ccc([N+](=O)[O-])cc1NC(=O)NC(C(=O)Nc1ccc(Br)cc1)c1ccccc1 -US20060106019A1,2,CN(c1ccccc1)c1ncnc2c(CCC(=O)O)cnn12.COC(=O)c1ccc(N)cc1>>COC(=O)c1ccc(NC(=O)CCc2cnn3c(N(C)c4ccccc4)ncnc23)cc1 -US05347039,7,CC(C)(C)SC(=O)CC(=O)CC(O)c1ccccc1>>CC(C)(C)SC(=O)CC(O)CC(O)c1ccccc1 -US07393868B2,7,CC(C)S(=O)(=O)Nc1cnccc1-c1ccc(-c2cc(F)c(OC(=O)C(C)(C)C)c(F)c2)cc1>>CC(C)S(=O)(=O)Nc1cnccc1-c1ccc(-c2cc(F)c(O)c(F)c2)cc1 -US20100197744A1,6,COC(=O)CN(c1cc(OCc2ccccc2)cc2ccc(OC)cc12)S(=O)(=O)NC(=O)OC(C)(C)C>>COC(=O)CN(c1cc(OCc2ccccc2)cc2ccc(OC)cc12)S(N)(=O)=O -US20080132549A1,1,CCc1nc(CO)n(CC)c1Sc1cc(C#N)cc(C#N)c1.O=C1NC(=O)c2ccccc21>>CCc1nc(CN2C(=O)c3ccccc3C2=O)n(CC)c1Sc1cc(C#N)cc(C#N)c1 -US20050228006A1,1,C1CC2(CCN1)OCCO2.Clc1nc2ccccc2[nH]1>>c1ccc2[nH]c(N3CCC4(CC3)OCCO4)nc2c1 -US07919502B2,2,COc1ccc(CN2CCNCC2)cc1.O=C(O)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1>>COc1ccc(CN2CCN(C(=O)c3ccc(-c4cnc5c(c4)N(Cc4cc(Cl)ccc4C(F)(F)F)CCN5)cc3)CC2)cc1 -US06919361B2,2,CCN.COc1cc(Cl)ccc1N=c1scc(-c2ccc(F)cc2)n1CCCN(CC(=O)O)C(=O)OC(C)(C)C>>CCNC(=O)CN(CCCn1c(-c2ccc(F)cc2)csc1=Nc1ccc(Cl)cc1OC)C(=O)OC(C)(C)C -US04279912,6,CCOC(=O)c1cn2c(ccc3cc(Cl)ccc32)n1>>O=C(O)c1cn2c(ccc3cc(Cl)ccc32)n1 -US20060040940A1,3,CC1(C)COB(c2cccc(SC(F)(F)F)c2)OC1.FC(F)(F)c1cnn2c(Br)cnc2n1>>FC(F)(F)Sc1cccc(-c2cnc3nc(C(F)(F)F)cnn23)c1 -US08247436B2,6,COC(=O)c1nc(-c2ccc(Cl)cc2Cl)c(C(F)(F)F)cc1N>>Nc1cc(C(F)(F)F)c(-c2ccc(Cl)cc2Cl)nc1C(=O)O -US08153644B2,2,CC(C)OC(=O)Cl.O=C(Nc1ccc(N2CCNCC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F>>CC(C)OC(=O)N1CCN(c2ccc(NC(=O)c3nc(-c4ccccc4)oc3C(F)(F)F)cn2)CC1 -US20150284367A1,1,CC(C)(O)c1cccc(Br)n1.CI>>COC(C)(C)c1cccc(Br)n1 -US20090149439A1,2,Cc1cc(C(=O)O)ncc1C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(F)cc1.OC1CCNCC1>>Cc1cc(C(=O)N2CCC(O)CC2)ncc1C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(F)cc1 -US06426417B1,2,CC(C)(C)C(=O)OC(=O)C(C)(C)C.CCOC(=O)CC[C@H](NC(=O)c1ccc(CCC2CNc3nc(N)[nH]c(=O)c3C2)s1)C(=O)OCC>>CCOC(=O)CC[C@H](NC(=O)c1ccc(CCC2CNc3nc(NC(=O)C(C)(C)C)[nH]c(=O)c3C2)s1)C(=O)OCC -US06710056B2,6,COC(=O)c1ccc(N)c2ccccc12>>Nc1ccc(C(=O)O)c2ccccc12 -US20120232081A1,8,Cc1c(F)cccc1Cc1c(-c2ccccc2)c2ccccn2c1C(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](CCO)C1>>Cc1c(F)cccc1Cc1c(-c2ccccc2)c2ccccn2c1C(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](CC=O)C1 -US07560569B2,2,CCCCCOc1ccc(N)cc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>CCCCCOc1ccc(NC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)cc1 -US20150238601A1,1,CC(C)NC(=O)COc1cccc(-c2nc(N)cc(Cl)n2)c1.CN1CCNCC1>>CC(C)NC(=O)COc1cccc(-c2nc(N)cc(N3CCN(C)CC3)n2)c1 -US20120094972A1,1,Cc1c(-c2ccccn2)nc2cc(F)ccc2c1Cl.c1cc2c(cc1N1CCOCC1)NCCO2>>Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CCOc2ccc(N3CCOCC3)cc21 -US06437146B1,6,COC(=O)c1ccc(CCNC(=O)OC(C)(C)C)cc1>>COC(=O)c1ccc(CCN)cc1 -US05476873,1,Brc1ccccn1.O=Cc1ccccc1O>>O=Cc1ccccc1Oc1ccccn1 -US06432950B1,1,FC(F)(F)c1cc2c(NCc3ccc(Cl)c(Cl)c3)nc(Cl)nc2s1.c1c[nH]cn1>>FC(F)(F)c1cc2c(NCc3ccc(Cl)c(Cl)c3)nc(-n3ccnc3)nc2s1 -US20030232866A1,4,C#Cc1cscn1.COc1cc(N)c(I)cc1-c1cnco1>>COc1cc2[nH]c(-c3cscn3)cc2cc1-c1cnco1 -US07557213B2,1,Cc1ccc(C(=O)c2c[nH]c3cccnc3c2=O)cc1C.Cc1cccc(CBr)n1>>Cc1cccc(Cn2cc(C(=O)c3ccc(C)c(C)c3)c(=O)c3ncccc32)n1 -US06495542B1,9,NO.O=C1CCCc2ccncc21>>ON=C1CCCc2ccncc21 -US05306830,1,C=CCBr.COc1ccc(Br)c(O)c1>>C=CCOc1cc(OC)ccc1Br -US07169789B2,2,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C=Nc1ccc(F)cc1>>COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(F)cc4)cc3)c2cc1OC -US20140296225A1,1,N#Cc1ccc2c(c1)CCC(N1CCNCC1=O)C2.O=CCc1ccc2nonc2c1>>N#Cc1ccc2c(c1)CCC(N1CCN(CCc3ccc4nonc4c3)CC1=O)C2 -US07939661B2,1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1ccc2c(I)ccnc2c1>>CC(C)(C)OC(=O)N1CCC(Nc2ccnc3cc(Cl)ccc23)CC1 -US20110046134A1,7,O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cc(-c2ccccc2[N+](=O)[O-])[nH]n1>>Nc1ccccc1-c1cc(C(=O)NCC(=O)N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)n[nH]1 -US06171756B2,2,CC(C)NC(C)C.CC(OC(=O)Cl)c1ccccc1[N+](=O)[O-]>>CC(OC(=O)N(C(C)C)C(C)C)c1ccccc1[N+](=O)[O-] -US20070167452A1,9,C=CCCC(CCOc1ccc(F)cc1)(C(=O)OCC)C(=O)OCC>>C=CCCC(CCOc1ccc(F)cc1)C(=O)OCC -US07825155B2,3,CCN(CC)[C@@H]1C[C@@H](CN2C(=O)C(=O)c3c2cc(I)cc3C(F)(F)F)C1.[Mg+]c1ccccc1Cl>>CCN(CC)[C@@H]1C[C@@H](CN2C(=O)C(O)(c3ccccc3Cl)c3c2cc(I)cc3C(F)(F)F)C1 -US20060063782A1,7,O=C(O)c1cc([N+](=O)[O-])ccc1F>>O=[N+]([O-])c1ccc(F)c(CO)c1 -US20140336106A1,6,O=C(CN1CCC(O)CC1)OCc1ccccc1>>O=C(O)CN1CCC(O)CC1 -US20100280001A1,1,CCCCc1nc2c(N)nc3ccccc3c2n1CCCNC1CCN(C)CC1.COC(=O)Cc1cccc(C=O)c1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(CC(=O)OC)c1)C1CCN(C)CC1 -US20140056849A1,1,CC(Cl)OC(=O)OC1CCCCC1.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2cn(C(C)OC(=O)OC3CCCCC3)c3ncc(-c4ccc(Cl)cc4)cc23)c1F -US20070254931A1,3,C=O.CC(=O)Nc1nc(/C=C\c2ccc([N+](=O)[O-])cc2)cs1.COC(=O)[C@@H]1CCNC1>>COC(=O)[C@@H]1CCN(Cc2sc(NC(C)=O)nc2/C=C\c2ccc([N+](=O)[O-])cc2)C1 -US20100210591A1,7,C[Si](C)(C)c1cc(C(=O)Nc2ccc(C=CC(=O)O)cc2)cc([Si](C)(C)C)c1>>C[Si](C)(C)c1cc(C(=O)Nc2ccc(CCC(=O)O)cc2)cc([Si](C)(C)C)c1 -US20140350019A1,1,CC(C)OC(=O)CBr.COc1cc(CNc2c(F)ccc(O)c2C)cc(-c2cccc(F)c2)c1>>COc1cc(CNc2c(F)ccc(OCC(=O)OC(C)C)c2C)cc(-c2cccc(F)c2)c1 -US06004959,6,CCCOc1ccc2c(c1)C(=O)c1cccc(OC)c1-2>>CCCOc1ccc2c(c1)C(=O)c1cccc(O)c1-2 -US20090270402A1,4,CC(C)(C=O)CO[Si](C)(C)C(C)(C)C.NNc1ccc(-c2c(-c3ccc(F)cc3F)nc3n2CCC3)nn1>>CC(C)(CO[Si](C)(C)C(C)(C)C)c1nnc2ccc(-c3c(-c4ccc(F)cc4F)nc4n3CCC4)nn12 -USRE039679E1,7,O=NN1CCCSc2ccccc21>>NN1CCCSc2ccccc21 -US20080227781A1,1,CCCC(N)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1.O=C1Cc2ccc(Cl)cc2C1>>CCCC(NC1Cc2ccc(Cl)cc2C1)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1 -US06288120B1,7,O=C(O)C=Cc1cc(Cl)cc(Cl)c1>>O=C(O)CCc1cc(Cl)cc(Cl)c1 -US06613942B1,1,COc1cc(C=O)cc(OC)c1OCc1ccc(C(C)C)cc1.NNC(=O)c1ccc(O)c(N)c1>>COc1cc(C=NNC(=O)c2ccc(O)c(N)c2)cc(OC)c1OCc1ccc(C(C)C)cc1 -US04447260,2,CC1(C(=O)O)CC1.Nc1ccc(OCC(F)(F)F)c(Cl)c1>>CC1(C(=O)Nc2ccc(OCC(F)(F)F)c(Cl)c2)CC1 -US08288552B2,2,COC(=O)Cl.Cc1ccc(O)c(F)c1F>>COC(=O)Oc1ccc(C)c(F)c1F -US05849801,2,CC(=O)OC(C)=O.CC1=CC(NCc2ccccc2)C(O)C(C)(C)CC1=O>>CC(=O)N(Cc1ccccc1)C1C=C(C)C(=O)CC(C)(C)C1O -US20080076924A1,2,CC(C)C1CN(c2ncc(C(=O)O)s2)CCN1C(=NC#N)Nc1cccc2ncccc12.CNC>>CC(C)C1CN(c2ncc(C(=O)N(C)C)s2)CCN1C(=NC#N)Nc1cccc2ncccc12 -US20150266857A1,2,CC(C)(C)OC(=O)NCC(=O)O.Nc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3cc(F)ccc23)cc1N>>CC(C)(C)OC(=O)NCC(=O)Nc1cc(-c2cn(S(=O)(=O)c3ccccc3)c3cc(F)ccc23)ccc1N -US20080255085A1,3,Clc1ccnc2[nH]c(-c3ccc(CN4CCOCC4)cc3)nc12.NC(=O)c1ccc(B(O)O)cc1>>NC(=O)c1ccc(-c2ccnc3[nH]c(-c4ccc(CN5CCOCC5)cc4)nc23)cc1 -US20070197559A1,1,Nc1c(Cl)ncnc1Cl.Nc1ccccc1Cl>>Nc1c(Cl)ncnc1Nc1ccccc1Cl -US08759348B2,1,Cc1cc(Cl)c2cc(I)ccc2n1.OCc1cccnc1>>Cc1cc(Cl)c2cc(OCc3cccnc3)ccc2n1 -US05559113,2,O=C=NCCc1ccccc1.OCCc1c[nH]cn1>>O=C(NCCc1ccccc1)OCCc1c[nH]cn1 -US20100280002A1,3,CN(C)c1ccc(B(O)O)cc1.Nc1ncc(Br)cc1[N+](=O)[O-]>>CN(C)c1ccc(-c2cnc(N)c([N+](=O)[O-])c2)cc1 -US06825208B2,2,COc1cc(C2Nc3ccc(C(=N)N)cc3C3c4ccccc4CC23)c(-c2ccc(C(=O)O)cc2OC)cc1O.NCCN1CCCC1>>COc1cc(C2Nc3ccc(C(=N)N)cc3C3c4ccccc4CC23)c(-c2ccc(C(=O)NCCN3CCCC3)cc2OC)cc1O -US20090156582A1,6,CC(C#N)(CNC(=O)c1nn(C2CCCCO2)cc1NC(=O)c1ccccn1)Cc1ccccc1>>CC(C#N)(CNC(=O)c1n[nH]cc1NC(=O)c1ccccn1)Cc1ccccc1 -US06838463B2,1,C#CCOc1cc(Cl)ncn1.Oc1cc(Cl)ccc1Cl>>C#CCOc1cc(Oc2cc(Cl)ccc2Cl)ncn1 -US06017919,7,N#CCc1ccc(OCc2ccccc2)cc1>>NCCc1ccc(OCc2ccccc2)cc1 -US08846661B2,3,Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1.Cc1noc(C)c1B(O)O>>Cc1noc(C)c1-c1cncc(N2CC3CC4CC2CN(C4)C3)c1 -US20120172333A1,2,CCOC(=O)c1c(N)cc(Cl)n1-c1ccc(C(C)=O)cc1.N#CCC(=O)O>>CCOC(=O)c1c(NC(=O)CC#N)cc(Cl)n1-c1ccc(C(C)=O)cc1 -US04791225,2,CC(=O)OC(C)=O.Nc1ccc(F)c(F)c1>>CC(=O)Nc1ccc(F)c(F)c1 -US20100297038A1,1,COc1ccc(CCN)cc1.O=[N+]([O-])c1ccccc1F>>COc1ccc(CCNc2ccccc2[N+](=O)[O-])cc1 -US20030139473A1,6,COC(=O)Cc1ccc(OC/C=C(\C)c2ccc(Oc3ccccc3)cc2)cc1>>C/C(=C\COc1ccc(CC(=O)O)cc1)c1ccc(Oc2ccccc2)cc1 -US20090163508A1,5,Brc1cccc(N2CCNCC2)c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(c2cccc(Br)c2)CC1 -US20040058932A1,6,C[C@H]1CN(C(=O)COc2ccc(Cl)cc2CNS(=O)(=O)CCN2C(=O)c3ccccc3C2=O)[C@H](C)CN1Cc1ccc(F)cc1>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2CNS(=O)(=O)CCN)[C@H](C)CN1Cc1ccc(F)cc1 -US05605901,2,C=COC(=O)Cl.NC1Cc2ccc(-c3ccc(=O)[nH]n3)cc2C1>>C=COC(=O)NC1Cc2ccc(-c3ccc(=O)[nH]n3)cc2C1 -US20140142074A1,2,COc1ccc(C(=O)SCC(=O)O)cc1OS(C)(=O)=O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>COc1ccc(C(=O)SCC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OS(C)(=O)=O -US08829035B2,7,O=[N+]([O-])c1cc(-c2nc3ccccc3o2)ccc1NCc1ccccc1>>Nc1cc(-c2nc3ccccc3o2)ccc1NCc1ccccc1 -US07157604B2,3,CCCCC1(CCC(=O)CC)Cc2cc(N)c(F)cc2C1=O>>CCCCC12CCC(=O)C(C)=C1c1cc(F)c(N)cc1C2 -US08269011B2,6,CCCOc1ccc(F)c2c(=O)c(-c3ccc(OC)cc3)c[nH]c12>>CCCOc1ccc(F)c2c(=O)c(-c3ccc(O)cc3)c[nH]c12 -US06995182B2,1,Cc1ccc(S(=O)(=O)N2C(CCCl)CCC2c2ccc(F)cc2)cc1.Cc1nnn[nH]1>>Cc1ccc(S(=O)(=O)N2C(CCn3nnnc3C)CCC2c2ccc(F)cc2)cc1 -US08431563B2,1,C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1.OCC(O)(c1ccc(Br)cc1)C(F)(F)F>>C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(O)(CO)C(F)(F)F)cc1 -US20110003833A1,1,C[Si](C)(C)CCOCn1ccc(N)n1.Cc1cc(Cl)nc(Cl)n1>>Cc1cc(Nc2ccn(COCC[Si](C)(C)C)n2)nc(Cl)n1 -US20050059662A1,6,C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N1C#N>>C[C@H]1CNC[C@@H](C)N1C#N -US20090221555A1,1,CCN1CCc2ccc(N)cc2CC1.CNC(=O)c1ccccc1Nc1nc(Cl)ncc1C>>CCN1CCc2ccc(Nc3ncc(C)c(Nc4ccccc4C(=O)NC)n3)cc2CC1 -US07470699B2,1,CS(=O)(=O)CCO.Cc1c(Nc2ccc(I)cc2F)ncnc1OC1CCN(C(=O)OC(C)C)CC1>>Cc1c(Nc2ccc(OCCS(C)(=O)=O)cc2F)ncnc1OC1CCN(C(=O)OC(C)C)CC1 -US06020379,1,CS.O=Cc1ccc(F)cc1-c1ccc(Cl)cc1>>CSc1ccc(-c2cc(F)ccc2C=O)cc1 -US20090247507A1,2,CC(C)(C)OC(=O)N1CCN(CC(=O)O)CC1.Nc1nccs1>>CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2nccs2)CC1 -US20040030129A1,2,CC(C)N.COC1=C(OC)C(=O)C(Cc2ccc(C(=O)O)cc2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(C(=O)NC(C)C)cc2)=C(C)C1=O -US20110190259A1,6,Cc1cc(OC(C)C)c(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)cc1C1(C)OCCO1>>CC(=O)c1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C -US20100227870A1,1,C1CNCCN1.Fc1ccc(C(F)(F)F)cc1Cl>>FC(F)(F)c1ccc(N2CCNCC2)c(Cl)c1 -US08404726B2,6,COC(=O)CCc1ccc(C(=O)CCc2nc(-c3ccccc3OC)oc2C(C)C)cc1C>>COC(=O)CCc1ccc(C(=O)CCc2nc(-c3ccccc3O)oc2C(C)C)cc1C -US07632857B2,3,COC(=O)c1ccc(Br)cc1.OB(O)c1cccnc1>>COC(=O)c1ccc(-c2cccnc2)cc1 -US20130289042A1,6,CC(=O)n1cc(CC2CCCN2C(=O)OC(C)(C)C)c2ccc(F)cc21>>CC(C)(C)OC(=O)N1CCCC1Cc1c[nH]c2cc(F)ccc12 -US20140088076A1,3,Cc1nc(B2OC(C)(C)C(C)(C)O2)cs1.O=C(Nc1cc2ccc(Br)cc2cn1)C1CC1>>Cc1nc(-c2ccc3cc(NC(=O)C4CC4)ncc3c2)cs1 -US09079866B2,3,Nc1cnc(-c2ccc(Br)cc2F)cn1.O=S(=O)(c1ccccc1B(O)O)N1CCCCC1>>Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCCCC3)cc2F)cn1 -US20140135332A1,10,CC(=O)OCCc1nc(-c2ccc(C(F)(F)F)cc2)c(Br)o1.O=C1CCC(=O)N1Br>>CC(=O)OCC(Br)c1nc(-c2ccc(C(F)(F)F)cc2)c(Br)o1 -US20130196974A1,9,Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NC(=O)C(C)(C)N=[N+]=[N-])c2c1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NC(=O)C(C)(C)N)c2c1 -US20040058978A1,1,CN.O=[N+]([O-])c1ccc(CCBr)cc1>>CNCCc1ccc([N+](=O)[O-])cc1 -US08143271B2,1,BrCc1ccccc1.Oc1ccc(F)cc1Cl>>Fc1ccc(OCc2ccccc2)c(Cl)c1 -US20070197621A1,6,CCc1ccc(OC)c(CC)c1C=O>>CCc1ccc(O)c(CC)c1C=O -US20090233908A1,6,O=C1c2ccccc2C(=O)N1CCS(=O)(=O)NC[C@@H]1[C@@H](Nc2nccc(N3CCCCCC3)n2)CCN1C1CCCCC1>>NCCS(=O)(=O)NC[C@@H]1[C@@H](Nc2nccc(N3CCCCCC3)n2)CCN1C1CCCCC1 -US07649093B2,3,CCCc1cc2cc(OC)ccc2c(OCOC)c1Br.OB(O)c1ccc(F)cc1>>CCCc1cc2cc(OC)ccc2c(OCOC)c1-c1ccc(F)cc1 -US20150051395A1,6,COC(=O)c1cc(F)c(NS(=O)(=O)c2ccccn2)cc1F>>O=C(O)c1cc(F)c(NS(=O)(=O)c2ccccn2)cc1F -US07718809B2,1,COC(=O)c1cc(O)c2nc(C)n(C)c2c1.Fc1cc(F)c2c(c1)OCCC2Cl>>COC(=O)c1cc(OC2CCOc3cc(F)cc(F)c32)c2nc(C)n(C)c2c1 -US20120022100A1,6,COCCCOc1cc(C[C@@H](C[C@H](N=[N+]=[N-])[C@H](C[C@H](C(=O)N[C@@H]2CCN(C)C2)C(C)C)O[Si](C)(C)C(C)(C)C)C(C)C)ccc1OC>>COCCCOc1cc(C[C@@H](C[C@H](N=[N+]=[N-])[C@@H](O)C[C@H](C(=O)N[C@@H]2CCN(C)C2)C(C)C)C(C)C)ccc1OC -US20070244125A1,1,N#CCBr.O=C(c1ccc2[nH]c(C(=O)N3CCC(F)(F)CC3)cc2c1)N1CCN(C2CCCC2)CC1>>N#CCn1c(C(=O)N2CCC(F)(F)CC2)cc2cc(C(=O)N3CCN(C4CCCC4)CC3)ccc21 -US06337394B2,9,N#Cc1ccc(CBr)c(Cl)c1.[N-]=[N+]=[N-]>>N#Cc1ccc(CN=[N+]=[N-])c(Cl)c1 -US20040082570A1,6,C=CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2c1c(=O)[nH]c(=O)n2C>>C=CCn1c(N2CCNCC2)nc2c1c(=O)[nH]c(=O)n2C -US20150224071A1,6,C=Cc1cc(C(=O)OC(C)(C)C)c(F)cc1OCC12CC3CC(CC(C3)C1)C2>>C=Cc1cc(C(=O)O)c(F)cc1OCC12CC3CC(CC(C3)C1)C2 -US20060229336A1,2,CCC(=O)Cl.Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)CC1>>CCC(=O)NS(=O)(=O)c1cc(C(=O)N2CCC(CCN3C4CCC3CC(n3c(C)nc5ccccc53)C4)(c3ccccc3)CC2)ccc1Cl -US04416884,1,C#CCBr.CC1CCc2c(N3CCNCC3)c(Cl)cc3c(=O)c(C(=O)O)cn1c23>>C#CCN1CCN(c2c(Cl)cc3c(=O)c(C(=O)O)cn4c3c2CCC4C)CC1 -US20070185097A1,1,COc1cc([N+](=O)[O-])ccc1Cl.OCCC1CCCO1>>COc1cc([N+](=O)[O-])ccc1OCCC1CCCO1 -US06683107B2,9,CCCCc1oc2ccccc2c1C(O)c1ccc(O)cc1>>CCCCc1oc2ccccc2c1Cc1ccc(O)cc1 -US20100261771A1,6,CCNC(=O)OCC(NC(=O)OC(C)(C)C)c1ccccc1C(F)(F)F>>CCNC(=O)OCC(N)c1ccccc1C(F)(F)F -US20100216746A1,6,COC(=O)c1[nH]cnc1Br>>O=C(O)c1[nH]cnc1Br -US20070010511A1,1,COCCCN1C(=O)CCc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(O)cc3)cc21.N#CCCCBr>>COCCCN1C(=O)CCc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCCC#N)cc3)cc21 -US20050037925A1,1,CC(=O)c1c(C)cc(C)c(C)c1O.CI>>COc1c(C)c(C)cc(C)c1C(C)=O -US20060025474A1,2,Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.O=C(Cl)C1CC1>>Cc1cc(C(C)(C)C)c(OC(=O)C2CC2)c(C(C)(C)C)c1 -US20050124620A1,3,Cc1ccc(S(=O)(=O)n2cc(C=O)c3ccccc32)cc1.c1ccc([P+](Cc2cccnc2)(c2ccccc2)c2ccccc2)cc1>>Cc1ccc(S(=O)(=O)n2cc(/C=C/c3cccnc3)c3ccccc32)cc1 -US20150126511A1,9,BrCc1ccc2ccccc2c1.[C-]#N>>N#CCc1ccc2ccccc2c1 -US20140088076A1,2,CC1(N)CCC1.Cc1ccc(C(=O)O)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1>>Cc1ccc(C(=O)NC2(C)CCC2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 -US20080161303A1,3,CC(C)Nc1nnc2cc(Br)ccn12.Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccn2c(NC(C)C)nnc2c1 -US20140094462A1,2,C=CC[C@@H](NC(=O)OC(C)(C)C)C(=O)O.CN[C@H](C)[C@H](O)c1ccccc1>>C=CC[C@@H](NC(=O)OC(C)(C)C)C(=O)N(C)[C@H](C)[C@H](O)c1ccccc1 -US20100152186A1,7,CCOC(=O)CC(C)n1cnnc1-c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>CC(CCO)n1cnnc1-c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20090149468A1,1,CC(C)(C)OC(=O)N1CC2CC1CN2.Clc1cc(-c2cc3nccn3c(Cl)n2)ccn1>>CC(C)(C)OC(=O)N1CC2CC1CN2c1nc(-c2ccnc(Cl)c2)cc2nccn12 -US07468369B2,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1ccc(C=O)cc1>>COC(=O)/C=C/c1ccc(C)cc1 -US07192943B2,7,Cn1ncc(N=O)c1N>>Cn1ncc(N)c1N -US20110178060A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CN(C(=O)N(C)[C@@H]1CCNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN(C(=O)N(C)[C@@H]1CCN(C2CCN(C(=O)OC(C)(C)C)CC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20100137308A1,1,CCOP(OCC)OCC.COc1ccc(CBr)c([N+](=O)[O-])c1>>CCOP(=O)(Cc1ccc(OC)cc1[N+](=O)[O-])OCC -US07691869B2,1,Fc1ccc(N2CCNCC2)c(F)c1.Nc1nc(Cl)c2ccn(CCBr)c2n1>>Nc1nc(Cl)c2ccn(CCN3CCN(c4ccc(F)cc4F)CC3)c2n1 -US20100048666A1,3,CC(C(=O)OC(C)(C)C)c1ccc(C=O)cc1.O=C1CCCSC1>>CC(C(=O)OC(C)(C)C)c1ccc(C=C2SCCCC2=O)cc1 -US08129361B2,7,O=C(O)CCc1ccc2c(c1)CCO2>>OCCCc1ccc2c(c1)CCO2 -US20050032787A1,6,Cc1c(C)n(CCOCc2ccccc2)c2ccccc12>>Cc1c(C)n(CCO)c2ccccc12 -US07737166B2,1,CCOC(=O)c1csc(-c2nc3c(C#N)c(C)c(-c4ccccc4)c(F)c3o2)n1.CN(C)[C@H]1CCNC1>>CCOC(=O)c1csc(-c2nc3c(C#N)c(C)c(-c4ccccc4)c(N4CC[C@H](N(C)C)C4)c3o2)n1 -US20120059028A1,6,CCCC(C(=O)OC)c1c(C)nc2scc(-c3ccccc3)c2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2scc(-c3ccccc3)c2c1-c1ccc(C)cc1 -US20090275593A1,7,CCOC(=O)c1cnn2c(N)c(-c3ccc([N+](=O)[O-])cc3)cnc12>>CCOC(=O)c1cnn2c(N)c(-c3ccc(N)cc3)cnc12 -US20110105530A1,2,COC(=O)c1ccnc(N2CCN(Cc3ccc(F)cc3)C2=O)c1.NCCC1CC1>>O=C(NCCC1CC1)c1ccnc(N2CCN(Cc3ccc(F)cc3)C2=O)c1 -US05811582,6,COc1cccc(C(C)(O)C(C)CN(C)C)c1>>CC(CN(C)C)C(C)(O)c1cccc(O)c1 -US20100137305A1,2,Nc1ccc(I)cc1F.O=C(O)C1CC1>>O=C(Nc1ccc(I)cc1F)C1CC1 -US20020086890A1,6,CC#CCOc1ccc(SCC2(C(=O)OCC)CCN(C(=O)OC(C)(C)C)CC2)cc1>>CC#CCOc1ccc(SCC2(C(=O)O)CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20120252865A1,6,CCOC(=O)c1cc(C)oc1-c1cccc(OC)c1>>COc1cccc(-c2oc(C)cc2C(=O)O)c1 -US07968583B2,1,COC(=O)c1ccncc1N.O=C1CCOCC1>>COC(=O)c1ccncc1NC1CCOCC1 -US20080064740A1,2,Cc1sc(C(=O)O)c2c1[C@H]1[C@@H](C2)C1(C)C.NCc1ccc(O)cc1>>Cc1sc(C(=O)NCc2ccc(O)cc2)c2c1[C@H]1[C@@H](C2)C1(C)C -US20150232481A1,1,CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(Cl)n2n1.C[C@H](CCCCOC1(C)CCNCC1)OCc1ccccc1>>CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(N3CCC(C)(OCCCC[C@@H](C)OCc4ccccc4)CC3)n2n1 -US20090149450A1,2,CC(C)(C)OC(=O)NC(C(=O)O)C(C)(C)F.CN>>CNC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)F -US08034812B2,2,Nc1cn2nc(I)ccc2n1.O=C(O)CC1CC1>>O=C(CC1CC1)Nc1cn2nc(I)ccc2n1 -US20060160832A1,1,Clc1ncnc2sccc12.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(Oc2ncnc3sccc23)cc1 -US03963745,2,COc1ccc(S(N)(=O)=O)cc1C(=O)O.NC1CCN(C2CCCCC2)C1>>COc1ccc(S(N)(=O)=O)cc1C(=O)NC1CCN(C2CCCCC2)C1 -US08299057B2,6,CN1CCN(c2ccc(C(=O)OC(C)(C)C)c([N+](=O)[O-])c2)CC1>>CN1CCN(c2ccc(C(=O)O)c([N+](=O)[O-])c2)CC1 -US05271867,3,CC(=O)Cl.CCCCCCCCOc1ccc(-c2ccccc2)cc1F>>CCCCCCCCOc1ccc(-c2ccc(C(C)=O)cc2)cc1F -US08383635B2,6,CCOC(=O)c1c(C)nc(SC)nc1Nc1cccc(C)c1>>CSc1nc(C)c(C(=O)O)c(Nc2cccc(C)c2)n1 -US04599341,3,Brc1ccsc1.Cc1ccccc1Br>>Cc1ccccc1-c1ccsc1 -US05684034,6,CCOC(=O)COc1ccc2c(c1)c(CC(N)=O)c(C)n2Cc1ccccc1>>Cc1c(CC(N)=O)c2cc(OCC(=O)O)ccc2n1Cc1ccccc1 -US08435980B2,1,CC(N)=O.O=S(=O)(c1ccccc1)n1cc(-c2cc(Cl)nc(Cl)c2)c2cccnc21>>CC(=O)Nc1cc(-c2cn(S(=O)(=O)c3ccccc3)c3ncccc23)cc(Cl)n1 -US20140080788A1,2,COC(=O)CC(=O)O.Cc1cccc(OCCCC(=O)N2CCCc3c(-c4cccc(COC(=O)N5CCNCC5)c4)cccc32)c1C>>Cc1cccc(OCCCC(=O)N2CCCc3c(-c4cccc(COC(=O)N5CCN(C(=O)CC(=O)O)CC5)c4)cccc32)c1C -US20100087506A1,3,CC[C@H]1C(=O)CCN1C(=O)OCc1ccccc1.CC[Mg+]>>CC[C@@H]1N(C(=O)OCc2ccccc2)CC[C@@]1(O)CC -US20120101137A1,1,COC(=O)c1cc(C(O)CCCNC(=O)OC(C)(C)C)sc1C>>COC(=O)c1cc(C2CCCN2C(=O)OC(C)(C)C)sc1C -US05326760,6,CC(C)C[C@H](N[C@H](CCO[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C)C(=O)NCc1ccccc1>>CC(C)C[C@H](N[C@H](CCO)C(=O)OC(C)(C)C)C(=O)NCc1ccccc1 -US06878705B2,1,CNCC(O)c1ccc(-c2ccccc2)o1.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)oc21>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2o1)CC(O)c1ccc(-c2ccccc2)o1 -US05281585,6,CCN(C(=O)OC(C)(C)C)[C@H](C)CC(=O)O>>CCN[C@H](C)CC(=O)O -US20090209536A1,1,CC(C)(C)c1ccc2c(N3CCCC3)nc(Cl)nc2c1.Nc1ccc(F)c(F)c1>>CC(C)(C)c1ccc2c(N3CCCC3)nc(Nc3ccc(F)c(F)c3)nc2c1 -US20070197512A1,2,CCCC(Br)C(=O)Cl.Cc1cc(C)c(O)c(N)c1>>CCCC(Br)C(=O)Nc1cc(C)cc(C)c1O -US07049444B2,1,CC(=O)c1cccnc1.NN>>CC(=NN)c1cccnc1 -US20100152208A1,6,CCOC(=O)CSc1nc(Cl)c2sc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2n1>>O=C(O)CSc1nc(Cl)c2sc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2n1 -US20130296327A1,6,COC(=O)[C@H](Cc1ccc(OC(=O)NC(C)C)cc1)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](N)Cc1ccc(OC(=O)NC(C)C)cc1 -US20100292210A1,1,CN(C)C(=O)N1Cc2ccc(Cl)nc2O[C@H](c2ccccc2)C1.COc1cc(N)ccc1-n1cnc(C)c1>>COc1cc(Nc2ccc3c(n2)O[C@H](c2ccccc2)CN(C(=O)N(C)C)C3)ccc1-n1cnc(C)c1 -US20120289549A1,2,N[C@@H]1C[C@H]2CN(c3ccc(OC(F)(F)F)cc3)C(=O)N2C1.O=S(=O)(Cl)c1ccccc1Cl>>O=C1N(c2ccc(OC(F)(F)F)cc2)C[C@@H]2C[C@@H](NS(=O)(=O)c3ccccc3Cl)CN12 -US20120295923A1,1,COC(=O)C[C@@H]1CC[C@@H](N)[C@H](c2ccc(C(F)(F)F)cc2)C1.O=CC1CCCC1>>COC(=O)C[C@@H]1CC[C@@H](NCC2CCCC2)[C@H](c2ccc(C(F)(F)F)cc2)C1 -US20080039360A1,7,CCCC1(C(C)(C)C)C=CC(C)O1>>CCCC1(C(C)(C)C)CCC(C)O1 -US20150087626A1,1,COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3)CC2)cc1.N#Cc1ccc(CBr)cc1>>COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(C#N)cc3)CC2)cc1 -US04255432,1,CCI.O=C1NCC2(CCN(Cc3ccccc3)CC2)O1>>CCN1CC2(CCN(Cc3ccccc3)CC2)OC1=O -US07101868B2,1,CN1CCC(N2CC(C)(C)c3ccc(NC(=O)c4cccnc4F)cc32)CC1.NCc1ccc(F)cc1>>CN1CCC(N2CC(C)(C)c3ccc(NC(=O)c4cccnc4NCc4ccc(F)cc4)cc32)CC1 -US20080076943A1,6,CCc1nn2ccccc2c1N(CC1CCOCC1)C(=O)OC(C)(C)C>>CCc1nn2ccccc2c1NCC1CCOCC1 -US20090318690A1,1,CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCNCC3)noc12.O=Cc1ccsc1>>CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCN(Cc4ccsc4)CC3)noc12 -US20050059710A1,3,C#C[Si](C)(C)C.Nc1ccc(I)cc1F>>C[Si](C)(C)C#Cc1ccc(N)c(F)c1 -US20070043014A1,6,CCOC(=O)c1ccc(C(=O)C(C)CC)cc1>>CCC(C)C(=O)c1ccc(C(=O)O)cc1 -US20050256127A1,1,CC1CCCN1CCc1ccc2cc(Br)ccc2c1.O=c1cccn[nH]1>>CC1CCCN1CCc1ccc2cc(-n3ncccc3=O)ccc2c1 -US20090209582A1,6,CC(C)(C)OC(=O)N1CCC(CN2CCC(CNC(=O)c3cccc4[nH]c(C(C)(C)C)nc34)CC2)CC1>>CC(C)(C)c1nc2c(C(=O)NCC3CCN(CC4CCNCC4)CC3)cccc2[nH]1 -US06063932,7,O=C(CCl)c1ccc(-c2ccc(SC(F)F)cc2)cc1>>OC(CCl)c1ccc(-c2ccc(SC(F)F)cc2)cc1 -US20080132477A1,1,C=COCC.COC(=O)c1cc(O)cc(NC(=O)OCc2ccccc2)c1>>CCOC(C)Oc1cc(NC(=O)OCc2ccccc2)cc(C(=O)OC)c1 -US06350878B1,7,C/C=C(\CC)C(C)(C)C(=O)OCC>>C/C=C(\CC)C(C)(C)CO -US05541229,6,CC(C)(C)OC(=O)c1ccccc1-c1ccc(Cn2c(-c3cscn3)nc3ccccc32)cc1>>O=C(O)c1ccccc1-c1ccc(Cn2c(-c3cscn3)nc3ccccc32)cc1 -US06943157B2,1,BrCc1ccccc1.CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](CO)C(=O)OCc1ccccc1 -US04101579,1,NC(=O)c1cc(C(=O)CBr)ccc1O.c1ccc(CNCc2ccccc2)cc1>>NC(=O)c1cc(C(=O)CN(Cc2ccccc2)Cc2ccccc2)ccc1O -US07820707B2,2,CCOC(=O)CC#N.NCCO>>N#CCC(=O)NCCO -US20080182875A1,1,CN(CCO)C(=O)c1ccc(C(=C2CCNCC2)c2cccc3cccnc23)cc1.O=Cc1cscn1>>CN(CCO)C(=O)c1ccc(C(=C2CCN(Cc3cscn3)CC2)c2cccc3cccnc23)cc1 -US20090029994A1,1,Clc1ncc(Br)cn1.OCc1ccc(C(F)(F)F)cc1CNCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>OCc1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(Br)cn1 -US20060063779A1,1,CN1CCNCC1.O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(CBr)cc1>>CN1CCN(Cc2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cc2)CC1 -US04816469,8,Cc1cc(CO)cc(C(F)(F)F)c1>>Cc1cc(C=O)cc(C(F)(F)F)c1 -US20050085520A1,7,O=C(O)c1cc(N2CCCC2=O)cc([N+](=O)[O-])c1>>Nc1cc(C(=O)O)cc(N2CCCC2=O)c1 -US20150175623A1,1,C1=COCCC1.CSc1nccc(CO)n1>>CSc1nccc(COC2CCCCO2)n1 -US20100240638A1,2,C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)O.COC(=O)CCCCCCCCCCCC1(S(N)(=O)=O)CC1>>C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)NS(=O)(=O)C1(CCCCCCCCCCCC(=O)OC)CC1 -US20040058978A1,2,CC(C)(C)OC(=O)NCC(=O)O.NCc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1>>CC(C)(C)OC(=O)NCC(=O)NCc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1 -US20080021012A1,3,CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C.Cc1cn(CC(=O)c2ccc(Br)cn2)cn1>>Cc1cn(CC(=O)c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)cn1 -US06713479B2,1,CS(=O)(=O)OCC1CCCN(C(=O)C2(c3ccc(Cl)cc3)CCC2)C1.Fc1ccccc1N1CCNCC1>>O=C(N1CCCC(CN2CCN(c3ccccc3F)CC2)C1)C1(c2ccc(Cl)cc2)CCC1 -US20140161736A1,1,Cc1cc(C=O)ccc1OCCOC(=O)c1ccc(COc2cccc([C@@H](NC(=O)O[C@H]3CN4CCC3CC4)c3ccccc3)c2)cc1.NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12>>Cc1cc(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)ccc1OCCOC(=O)c1ccc(COc2cccc([C@@H](NC(=O)O[C@H]3CN4CCC3CC4)c3ccccc3)c2)cc1 -US06005103,6,CCOC(=O)COc1ccc(-c2cc(O)c(SCCc3ccccc3)c(=O)o2)cc1>>O=C(O)COc1ccc(-c2cc(O)c(SCCc3ccccc3)c(=O)o2)cc1 -US20080262021A1,7,N#CCc1ccc([N+](=O)[O-])cc1F>>N#CCc1ccc(N)cc1F -US20060122065A1,2,COc1cc(CCC(=O)O)ccc1O.NCc1ccc2ccccc2c1>>COc1cc(CCC(=O)NCc2ccc3ccccc3c2)ccc1O -US07652061B2,6,CCOC(=O)[C@H]1CCCN1C(=O)Sc1cccc(O[Si](C)(C)C(C)(C)C)c1>>CCOC(=O)[C@H]1CCCN1C(=O)Sc1cccc(O)c1 -US20050112770A1,9,Brc1ccc(Br)nc1.NN>>NNc1ccc(Br)cn1 -US20120220577A1,2,Nc1cccc(CO)c1.O=C(Cl)CCl>>O=C(CCl)Nc1cccc(CO)c1 -US06552011B1,1,C=COCC.C[C@H](CO[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C>>CCOC(C)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CO[Si](C)(C)C(C)(C)C)[C@@]4(C)CC[C@@H]32)C1(C)C -US07429585B2,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.Oc1cccc2sc(N3CCNCC3)nc12>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2nc3c(O)cccc3s2)CC1 -US20110124618A1,6,CCOC(=O)c1cc(-c2cccc(F)c2)n(-c2cccc(OC)c2)n1>>COc1cccc(-n2nc(C(=O)O)cc2-c2cccc(F)c2)c1 -US04958026,6,Oc1ccc(CCNCc2ccccc2)c2cn[nH]c12>>NCCc1ccc(O)c2[nH]ncc12 -US20110144090A1,6,CN(C)CCc1cn(Cc2ccccc2)c2c(F)ccc(OCc3ccccc3)c12>>CN(C)CCc1cn(Cc2ccccc2)c2c(F)ccc(O)c12 -US04570006,1,CC(=O)Oc1ccc(C=CC(=O)O)cc1.CS(=O)(=O)Oc1ccc(C(=N)N)cc1C(=O)c1ccccc1>>CC(=O)Oc1ccc(C=CC(=O)Oc2ccc(C(=N)N)cc2C(=O)c2ccccc2)cc1 -US03979396,6,COC(=O)CCCCC1SCC(C(=O)OC)=C1N>>COC(=O)C1=C(N)C(CCCCC(=O)O)SC1 -US20130210769A1,1,COc1ccc(I)cc1.O=C1NCC(c2cccc(C(F)(F)F)c2)N1c1ccc(Oc2ccc(Cl)cc2)cc1>>COc1ccc(N2CC(c3cccc(C(F)(F)F)c3)N(c3ccc(Oc4ccc(Cl)cc4)cc3)C2=O)cc1 -US09108981B2,6,C=C[C@H](NC(=O)OC(C)(C)C)c1cccc(Cl)c1>>C=C[C@H](N)c1cccc(Cl)c1 -US08163793B2,2,N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2)CC1.O=C(Cl)OC1CCCC1>>N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2C(=O)OC2CCCC2)CC1 -US20070219210A1,9,CCOC(=O)c1cc(-c2ccc(Br)cc2)n(-c2cccnc2)n1.[C-]#N>>CCOC(=O)c1cc(-c2ccc(C#N)cc2)n(-c2cccnc2)n1 -US07247625B2,1,CN1C(=O)OC(C)(c2ccc(Cl)cc2)c2cc(N)ccc21.OB(O)c1ccc(Br)cc1>>CN1C(=O)OC(C)(c2ccc(Cl)cc2)c2cc(Nc3ccc(Br)cc3)ccc21 -US20120264737A1,2,Cc1cc(C2CCC2)c(-c2nnc[nH]2)cc1C(=O)O.N#Cc1ccc(C2(F)CCNCC2)cc1>>Cc1cc(C2CCC2)c(-c2nnc[nH]2)cc1C(=O)N1CCC(F)(c2ccc(C#N)cc2)CC1 -US20040063720A1,2,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(C(=O)O)C1.CC(C)N>>CC(C)NC(=O)C1CN(C(=O)OC(C)(C)C)CCN1C(=O)OCc1ccccc1 -US05550125,7,CCOC(=O)CC1COc2ccc(Cl)cc2N1>>OCCC1COc2ccc(Cl)cc2N1 -US08362248B2,1,Cc1nc(F)ccc1[N+](=O)[O-].OCCS>>Cc1nc(SCCO)ccc1[N+](=O)[O-] -US07405305B2,1,CC(C)(C)OCCO.Oc1ccc2[nH]ccc2c1>>CC(C)(C)OCCOc1ccc2[nH]ccc2c1 -US20080070935A1,1,Cc1c[nH]c2c1C(=O)CC(C)(C)C2.Nc1ncc(Br)c2cc(F)ccc12>>Cc1cn(-c2ccc3c(N)ncc(Br)c3c2)c2c1C(=O)CC(C)(C)C2 -US05242919,1,CC=CCBr.Cc1ccc(O)c2c1C(c1ccccc1)C(C)C2=O>>CC=CCOc1ccc(C)c2c1C(=O)C(C)C2c1ccccc1 -US07560569B2,2,C=Cc1ccc(N)cc1.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>C=Cc1ccc(NC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)cc1 -US20080312231A1,3,C1CCNCC1.O=CC1CCC2(CC1)OCCO2.[C-]#N>>N#CC(C1CCC2(CC1)OCCO2)N1CCCCC1 -US20090221555A1,1,CCN1C(=O)CCC(C)(C)c2ccc(N)cc21.CN(C)c1ccc(Nc2nc(Cl)ncc2Cl)c(S(=O)(=O)N(C)C)c1>>CCN1C(=O)CCC(C)(C)c2ccc(Nc3ncc(Cl)c(Nc4ccc(N(C)C)cc4S(=O)(=O)N(C)C)n3)cc21 -US20150259343A1,1,CC1(C2CCNc3ccccc32)COC1.NC(=O)CI>>CC1(C2CCN(CC(N)=O)c3ccccc32)COC1 -US20130116241A1,3,O=c1[nH]ccc2occ(Br)c12.OB(O)c1ccncc1>>O=c1[nH]ccc2occ(-c3ccncc3)c12 -US20080300242A1,1,C1CNCCN1.COc1cc(F)ccc1[N+](=O)[O-]>>COc1cc(N2CCNCC2)ccc1[N+](=O)[O-] -US20060183909A1,7,COC(=O)c1cc(C#Cc2ccccc2)c2cccc(N)c2n1>>COC(=O)c1cc(CCc2ccccc2)c2cccc(N)c2n1 -US07307165B2,3,CCC[Zn+].Clc1cn2nc(Cl)ccc2n1>>CCCc1ccc2nc(Cl)cn2n1 -US04393052,6,CO[C@H]1C[C@H](NC(=O)C(F)(F)F)[C@@H](C)[C@H](C)O1>>C[C@@H]1O[C@@H](O)C[C@H](NC(=O)C(F)(F)F)[C@H]1C -US05929067,6,CCOC(=O)CCC(C(c1ccccc1)c1ccccc1)N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCC(=O)O)C(c1ccccc1)c1ccccc1 -US20130137687A1,1,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2Cl)CN1C(=O)C1(c2ccc(Cl)cc2)CC1.C[C@@H](O)C(F)(F)F>>COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(O[C@@H](C)C(F)(F)F)cc2Cl)CN1C(=O)C1(c2ccc(Cl)cc2)CC1 -US08349880B2,3,COc1cc(Nc2nc3c(s2)CCCC3=O)ccc1-n1cnc(C)n1.[Mg+]c1ccccc1>>COc1cc(Nc2nc3c(s2)CCCC3(O)c2ccccc2)ccc1-n1cnc(C)n1 -US08987248B2,2,CCc1ccc(C2CC(N)CN(C(=O)N3CCCC3)C2)cc1.O=C(Cl)Oc1ccccc1>>CCc1ccc(C2CC(NC(=O)Oc3ccccc3)CN(C(=O)N3CCCC3)C2)cc1 -US08293734B2,4,C=C(C)COc1ccc(OCc2ccccc2)cc1.O=C(OO)c1cccc(Cl)c1>>CC1(COc2ccc(OCc3ccccc3)cc2)CO1 -US20050234081A1,2,COc1cc(C)c(-c2cccc(S(=O)(=O)c3cc(C(=N)NC(=O)OC(C)(C)C)sc3SC)c2)c(N)c1.O=C(Br)CBr>>COc1cc(C)c(-c2cccc(S(=O)(=O)c3cc(C(=N)NC(=O)OC(C)(C)C)sc3SC)c2)c(NC(=O)CBr)c1 -US20140249126A1,2,CCn1cc(C(=O)O)c(=O)c2c(F)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21.NCCN1CCCC1>>CCn1cc(C(=O)NCCN2CCCC2)c(=O)c2c(F)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21 -US20100075946A1,6,CCOC(=O)c1cc(-c2ccccc2)c(C(F)(F)F)s1>>O=C(O)c1cc(-c2ccccc2)c(C(F)(F)F)s1 -US20100048636A1,7,COC12CCC(CC1)CC2=O>>COC12CCC(CC1)CC2 -US07109186B2,1,CC1(C)OC(=O)C(=CC(=O)Cl)O1.CONCc1ccc(F)cc1SC>>CON(Cc1ccc(F)cc1SC)C(=O)C=C1OC(C)(C)OC1=O -US05000946,2,CC(=O)C1=CNCCC1.O=C(Cl)c1ccccc1>>CC(=O)C1=CN(C(=O)c2ccccc2)CCC1 -US08377923B2,9,CCOC(=O)c1nnc(-c2cc(Cl)ccc2O[C@@H](C)c2nnc(-c3ccccc3C(F)(F)F)n2C)o1.N>>C[C@H](Oc1ccc(Cl)cc1-c1nnc(C(N)=O)o1)c1nnc(-c2ccccc2C(F)(F)F)n1C -US20020193402A1,6,O=C1C[C@@]2(c3ccccc3)[C@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC[C@@H]1N2Cc1ccccc1>>O=C1C[C@]2(c3ccccc3)N[C@H]1CC[C@H]2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US05972984,1,CC[C@H](C)[C@@H](C=O)NC(=O)OC(C)(C)C.NCc1cccc2ccccc12>>CC[C@H](C)[C@@H](CNCc1cccc2ccccc12)NC(=O)OC(C)(C)C -US20090200514A1,1,C=C[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](COS(C)(=O)=O)CC2)CC1.Oc1cccc(F)c1F>>C=C[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](COc3cccc(F)c3F)CC2)CC1 -US08252935B2,6,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCN(CCC(C)C)CC2)c1>>CC(C)CCN1CCC(c2cc(-c3ccc(C(F)(F)F)cc3)cc(C(CC(C)C)C(=O)O)c2)CC1 -US20150045427A1,7,CO[C@@H]1[C@H](OC(=O)/C=C/C=C/C=C/C=C/C(=O)O)CC[C@]2(CO2)[C@H]1[C@@]1(C)O[C@@H]1CC=C(C)C>>CO[C@@H]1C(O)CC[C@]2(CO2)C1[C@@]1(C)O[C@@H]1CC=C(C)C -US20100286190A1,7,Cc1ccc2c(ncn2Cc2ccncc2)c1[N+](=O)[O-]>>Cc1ccc2c(ncn2Cc2ccncc2)c1N -US04689338,1,CC(C)(O)CN.O=[N+]([O-])c1cnc2ccccc2c1Cl>>CC(C)(O)CNc1c([N+](=O)[O-])cnc2ccccc12 -US20110136821A1,9,N.O=C(O)CC1CC2(CCN(C(=O)/C=C/c3ccccc3C(F)(F)F)CC2)c2cc(F)ccc21>>NC(=O)CC1CC2(CCN(C(=O)/C=C/c3ccccc3C(F)(F)F)CC2)c2cc(F)ccc21 -US20060094743A1,10,COCOc1nc2c(c(C)nn2C)c2ccccc12.O=C1CCC(=O)N1Br>>COCOc1nc2c(c(CBr)nn2C)c2ccccc12 -US20070213364A1,1,CC(C)(C)c1cc(C(C)(C)C)[nH]n1.CCOC(=O)CCc1ccc(OCc2ccc(CCl)cc2)cc1F>>CCOC(=O)CCc1ccc(OCc2ccc(Cn3nc(C(C)(C)C)cc3C(C)(C)C)cc2)cc1F -US20110092529A1,1,OCCC1=CCN(Cc2ccccc2)CC1.Oc1ccccc1Br>>Brc1ccccc1OCCC1=CCN(Cc2ccccc2)CC1 -US07919502B2,3,CC1(C)OB(c2ccc(C#N)nc2)OC1(C)C.Fc1ccc(F)c(CN2CCNc3ncc(I)cc32)c1>>N#Cc1ccc(-c2cnc3c(c2)N(Cc2cc(F)ccc2F)CCN3)cn1 -US08415379B2,2,Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)O)nc1.NN1CCOCC1>>Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NN2CCOCC2)nc1 -US05169857,7,COC(=O)c1c(-c2ccc(F)cc2)cc(C)nc1C>>Cc1cc(-c2ccc(F)cc2)c(CO)c(C)n1 -US06515179B2,2,NC(c1ccccc1)c1ccccc1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>O=[N+]([O-])c1ccc(S(=O)(=O)NC(c2ccccc2)c2ccccc2)cc1 -US20110263548A1,6,CS(=O)(=O)c1ccc(-n2ccc(OCc3ccccc3)cc2=O)cc1>>CS(=O)(=O)c1ccc(-n2ccc(O)cc2=O)cc1 -US09040690B2,2,O=C(O)c1sc(-c2ccccc2)cc1N1C(=O)CNCC1C1CCCCC1.O=S(=O)(Cl)c1ccc(Cl)nc1>>O=C(O)c1sc(-c2ccccc2)cc1N1C(=O)CN(S(=O)(=O)c2ccc(Cl)nc2)C[C@H]1C1CCCCC1 -US04365062,2,CC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(N)C2SC1.CON=C(C(=O)O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C)CSC12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US08198271B2,6,CN(C)CCN(Cc1ccc(C(=O)Nc2cscc2NC(=O)OC(C)(C)C)nc1)C(=O)Nc1ccc2c(c1)OCCO2>>CN(C)CCN(Cc1ccc(C(=O)Nc2cscc2N)nc1)C(=O)Nc1ccc2c(c1)OCCO2 -US20070032470A1,2,COC(=O)c1cc(Br)cc(C(=O)O)c1.C[C@@H](N)c1ccccc1>>COC(=O)c1cc(Br)cc(C(=O)N[C@H](C)c2ccccc2)c1 -US20040127546A1,6,COc1ccc2c(C)c(C)[nH]c2c1>>Cc1[nH]c2cc(O)ccc2c1C -US08791102B2,2,COc1ccccc1N1CCN(CC(=O)O)CC1.N[C@@H](COCc1ccccc1)C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1>>COc1ccccc1N1CCN(CC(=O)N[C@@H](COCc2ccccc2)C(=O)Nc2ccc(Oc3ccc(F)cc3)cc2)CC1 -US05574064,6,CC(COc1ccc(C#N)cc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C>>CC(COc1ccc(C#N)cc1)NC(=O)[C@@H](N)C(C)C -US05344843,1,BrCCCCOc1ccccc1.COC(=O)C(=O)c1ccc(O)cc1>>COC(=O)C(=O)c1ccc(OCCCCOc2ccccc2)cc1 -US20050267304A1,1,CI.N#Cc1n[nH]c2ccccc12>>Cn1nc(C#N)c2ccccc21 -US20100256134A1,2,CCOC(=O)c1cnn2c(Nc3cc(C)ccc3C)c(C(=O)O)cnc12.Fc1ccc(C2CCNCC2)cc1F>>CCOC(=O)c1cnn2c(Nc3cc(C)ccc3C)c(C(=O)N3CCC(c4ccc(F)c(F)c4)CC3)cnc12 -US08524751B2,3,COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1N.C[C@H]1CN(Cc2nnc(-c3cc(Br)cc4c3cnn4S(=O)(=O)c3ccccc3)o2)C[C@@H](C)O1>>COc1ncc(-c2cc(-c3nnc(CN4C[C@H](C)O[C@H](C)C4)o3)c3cnn(S(=O)(=O)c4ccccc4)c3c2)cc1N -US20140088084A1,1,CC(Cl)C(=O)NC(CO)(c1cc(Br)ccc1F)C(F)F>>CC1OCC(c2cc(Br)ccc2F)(C(F)F)NC1=O -US05096919,4,CC(=O)CCC(C)=O.COC(=O)C=Cc1ccc(N)cc1>>COC(=O)C=Cc1ccc(-n2c(C)ccc2C)cc1 -US06423840B1,1,CC(C)(C)OC(=O)N[C@H]1CNc2ccccc2NC1=O.COC(=O)CBr>>COC(=O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CNc2ccccc21 -US04306097,6,CC=CC[C@@H]1CCC2(C[C@H]1c1ccc(C(C)(C)CCCCCC)cc1OCc1ccccc1)OCCO2>>CC=CC[C@@H]1CCC(=O)C[C@H]1c1ccc(C(C)(C)CCCCCC)cc1OCc1ccccc1 -US20090082329A1,1,Brc1cccnc1.CC1(C)C(=O)N(c2ccc(SC(F)(F)F)cc2)C(=O)N1Cc1ccnc(N)n1>>CC1(C)C(=O)N(c2ccc(SC(F)(F)F)cc2)C(=O)N1Cc1ccnc(Nc2cccnc2)n1 -US20150133446A1,1,CCc1cc(OCc2cccc(OCc3ccccc3)c2)c2cc(-c3cn4nc(Br)sc4n3)oc2c1.C[O-]>>CCc1cc(OCc2cccc(OCc3ccccc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US07674801B2,3,CN(C)C=O.O=C(O)c1ccc(Cl)nc1>>O=Cc1cc(Cl)ncc1C(=O)O -US07019003B2,1,CCCCNN.O=C(Cl)Oc1ccccc1>>CCCCN(N)C(=O)Oc1ccccc1 -US20080004295A1,2,CCCNC.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CCCN(C)C(=O)c1ccc([N+](=O)[O-])cc1 -US06235731B1,1,CC(C)(C)OC(=O)N1CCC(=CCBr)CC1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCC(=CCN2C(=O)c3ccccc3C2=O)CC1 -US20110071175A1,1,O=Cc1ncsc1Cl.O=S(O)c1ccccn1>>O=Cc1ncsc1S(=O)(=O)c1ccccn1 -US20030199689A1,1,COC(=O)c1cc2ccccc2[nH]1.Clc1ccc(-c2cc(CBr)no2)s1>>COC(=O)c1cc2ccccc2n1Cc1cc(-c2ccc(Cl)s2)on1 -US20110112120A9,1,CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.COc1ccc(B(O)O)cc1C>>CCCCc1nc(C)n(-c2ccc(OC)c(C)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US06576643B2,3,COc1ccc2c(c1)C(=O)CC2.[Mg+]c1ccccc1>>COc1ccc2c(c1)C(O)(c1ccccc1)CC2 -US09051265B2,6,COC(=O)c1cccc(Cn2c(C)c(C)c3cc(C(=O)N[C@@H](C)c4cccc(C5CC5)c4)ccc32)c1>>Cc1c(C)n(Cc2cccc(C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(C4CC4)c3)cc12 -US20130072467A1,2,CN1CCNCC1.O=C(O)CNC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1>>CN1CCN(C(=O)CNC2=NC(=O)S/C2=C\C2CCN(Cc3ccc(C(F)(F)F)cc3C(F)(F)F)CC2)CC1 -US06677383B1,3,CCC(=O)c1cc(OC)c(OC)c(OC)c1.COc1ccc(C=O)cc1>>COc1ccc(/C=C(\C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1 -US20080119518A1,2,C=CCc1cc(N)ccc1OC.O=C(Cl)CCCBr>>C=CCc1cc(NC(=O)CCCBr)ccc1OC -US04273704,6,COC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)[C@@H](C)O>>C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)O -US20070123495A1,4,N#CCOc1ccc2cc(-c3ccc(-c4ccccc4)n3Cc3ccccc3)ccc2c1.[N-]=[N+]=[N-]>>c1ccc(Cn2c(-c3ccccc3)ccc2-c2ccc3cc(OCc4nnn[nH]4)ccc3c2)cc1 -US06867218B2,1,C/C(=C\CO)c1ccc(-c2ccc(C(C)C)cc2)cc1.CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC>>CCOC(=O)[C@H](Cc1ccc(OC/C=C(\C)c2ccc(-c3ccc(C(C)C)cc3)cc2)cc1)OCC -US04480118,9,COC(=O)C1(C(=O)OC)Cc2ccc(Cl)cc2C1>>COC(=O)C1Cc2ccc(Cl)cc2C1 -US09050344B2,3,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncc(N)cc1Br.Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(B3OC(C)(C)C(C)(C)O3)c21>>Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3cc(N)cnc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)OC(C)(C)C)c21 -US20130045986A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CS(=O)(=O)c1ccc(-c2nc3cc(Br)ccc3s2)c(F)c1>>CC1(C)OB(c2ccc3sc(-c4ccc(S(C)(=O)=O)cc4F)nc3c2)OC1(C)C -US20130281433A1,6,CC(C)N1CCN(C(=O)OC(C)(C)C)[C@H](C)C1>>CC(C)N1CCN[C@H](C)C1 -US07919506B2,1,Cc1cc(Br)c(CN)cc1C(F)(F)F.O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(Br)c(CNCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C(F)(F)F -US20130245000A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Cl)nc2)CC1.CS(=O)(=O)c1ccc2c(c1)CCN2>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(N3CCc4cc(S(C)(=O)=O)ccc43)nc2)CC1 -US20100249165A1,3,CCOC(=O)NC(=O)c1cc2cc(Br)ccc2oc1=O.OB(O)c1ccco1>>CCOC(=O)NC(=O)c1cc2cc(-c3ccco3)ccc2oc1=O -US04851535,6,CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc(N3CCNCC3)c(F)cc2c1=O>>O=C(O)c1cn(-c2ccc(F)cc2F)c2nc(N3CCNCC3)c(F)cc2c1=O -US20080132481A1,1,CCN(CC)C(=O)CCl.O=C(O)c1[nH]c2ccccc2c1Nc1ccncc1>>CCN(CC)C(=O)COC(=O)c1[nH]c2ccccc2c1Nc1ccncc1 -US07718679B2,2,CCOC(=O)c1nc(CNC(=O)c2ccc(Cl)s2)no1.Nc1ccc(N2CCOCC2=O)cc1F>>O=C(Nc1ccc(N2CCOCC2=O)cc1F)c1nc(CNC(=O)c2ccc(Cl)s2)no1 -US05217952,6,CCC/C=C\c1ccccc1/C=C/C(=O)OCC>>CCC/C=C\c1ccccc1/C=C/C(=O)O -US06399774B1,6,COc1ccc2c(c1)C(C)(C)CN(C=O)C2>>CC1(C)CN(C=O)Cc2ccc(O)cc21 -US20120258950A1,2,Cn1cc(C(=O)c2cncc(N)c2)c2cncnc21.O=C=Nc1ccc(Cl)cc1>>Cn1cc(C(=O)c2cncc(NC(=O)Nc3ccc(Cl)cc3)c2)c2cncnc21 -US08524909B2,6,CC(C)(C)OC(=O)N[C@@H]1COCC[C@H]1N1CCCC1>>NC1COCCC1N1CCCC1 -US20130131037A1,1,C=O.O=c1ccc(-c2cc(F)cc(F)c2)nn1Cc1cccc(-c2ncc(C3CCNCC3)s2)c1>>CN1CCC(c2cnc(-c3cccc(Cn4nc(-c5cc(F)cc(F)c5)ccc4=O)c3)s2)CC1 -US08377942B2,9,NO.O=Cc1ccc(-n2cncn2)c2ccccc12>>ON=Cc1ccc(-n2cncn2)c2ccccc12 -US08436008B2,2,CNC.Cc1cc(-c2ccc3c(c2)CN(c2cc(N4CCN(C)CC4)nc(N)n2)CC3)cnc1C(=O)O>>Cc1cc(-c2ccc3c(c2)CN(c2cc(N4CCN(C)CC4)nc(N)n2)CC3)cnc1C(=O)N(C)C -US07179823B1,3,CCOC(=O)CCc1cn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)nc1OS(=O)(=O)C(F)(F)F.COc1ccc(B(O)O)cc1>>CCOC(=O)CCc1cn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)nc1-c1ccc(OC)cc1 -US08134013B2,6,CC(=NNC(=O)c1ccc(C(=O)NCC(=O)OC(C)(C)C)s1)c1csc(-c2ccc(Cl)c(Cl)c2)c1O>>CC(=NNC(=O)c1ccc(C(=O)NCC(=O)O)s1)c1csc(-c2ccc(Cl)c(Cl)c2)c1O -US20040235822A1,3,Brc1cnc2n1CCCC2.CN(C)C=O>>O=Cc1cnc2n1CCCC2 -US04649160,2,CS(=O)(=O)Cl.Cc1ccc(CCOCCO)cc1>>Cc1ccc(CCOCCOS(C)(=O)=O)cc1 -US08026261B2,1,CI.Cc1[nH]cc(C(O)C(F)(F)F)c(=O)c1OCc1ccccc1>>Cc1c(OCc2ccccc2)c(=O)c(C(O)C(F)(F)F)cn1C -US20140023611A1,1,CN.O=C(Nc1ccc(N2CCCCC2)cc1C(=O)N/N=C/c1ccc(Cl)c(C(F)(F)F)c1)c1cccc(CBr)c1>>CNCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)c1 -US20120133273A1,1,COC(=N)C(C)C.O=C(Cl)c1ccccc1>>COC(=NC(=O)c1ccccc1)C(C)C -US08497368B2,3,C[Mg+].Cn1ncc2cc(C(=O)c3cnc4ccc(Cl)nn34)ccc21>>Cn1ncc2cc(C(C)(O)c3cnc4ccc(Cl)nn34)ccc21 -US06063928,9,CCOC(=O)C(C(=O)OCC)c1cc(F)cc(OCc2ccccc2)c1>>CCOC(=O)Cc1cc(F)cc(OCc2ccccc2)c1 -US06569890B2,4,CCOC(=O)C(CC(=O)c1ccccc1)C(C)=O.CN(C)c1cccc(N)c1>>CCOC(=O)c1cc(-c2ccccc2)n(-c2cccc(N(C)C)c2)c1C -US20070142379A1,1,C#Cc1ccc(OCc2ccccc2)cc1.CCCC[SnH](CCCC)CCCC>>C=C(c1ccc(OCc2ccccc2)cc1)[Sn](CCCC)(CCCC)CCCC -US04065563,9,Nc1ccc(-c2nc(-c3ccco3)no2)cc1.S=C(Cl)Cl>>S=C=Nc1ccc(-c2nc(-c3ccco3)no2)cc1 -US20100226881A1,3,CCCC[Sn](CCCC)(CCCC)C1CC1.O=Cc1cnn2ccc(Br)cc12>>O=Cc1cnn2ccc(C3CC3)cc12 -US20100144760A1,6,Cc1ccc(-c2ncccn2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CN2C(=O)c3ccccc3C2=O)n1>>Cc1ccc(-c2ncccn2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CN)n1 -US20070123532A1,1,COC[C@@H]1CNCCO1.ClCCCBr>>COC[C@@H]1CN(CCCCl)CCO1 -US20090137804A1,1,CCN(CC)c1ccc(N)cc1.CNc1cc(Cl)ncn1>>CCN(CC)c1ccc(Nc2cc(NC)ncn2)cc1 -US20070225349A1,6,CCCCCn1nc(-c2ccc(OC)cc2)c2cccc(Cl)c21>>CCCCCn1nc(-c2ccc(O)cc2)c2cccc(Cl)c21 -US20060079523A1,1,FC(F)(F)c1ccc(S)nc1.O=Cc1ccc(F)cc1>>O=Cc1ccc(Sc2ccc(C(F)(F)F)cn2)cc1 -US20130231329A1,8,Cc1cccc(C(O)c2nc3ccccc3s2)c1>>Cc1cccc(C(=O)c2nc3ccccc3s2)c1 -US05866566,1,NC(=O)N1c2ccccc2CC(=O)c2ccccc21.NNc1ccccc1>>NC(=O)N1c2ccccc2CC(=NNc2ccccc2)c2ccccc21 -US20080221107A1,3,CC(C)(C)OC(=O)N1CCC(=O)C1.C[Mg+]>>CC1(O)CCN(C(=O)OC(C)(C)C)C1 -US20110190302A1,1,CC(=O)[O-].O=C(CBr)c1cccc([N+](=O)[O-])c1>>CC(=O)OCC(=O)c1cccc([N+](=O)[O-])c1 -US04254124,1,ClCCCBr.FC(F)(F)c1cccc(N2CCNCC2)c1>>FC(F)(F)c1cccc(N2CCN(CCCCl)CC2)c1 -US07812017B2,2,O=S(=O)(Cl)c1ccccc1.c1cc(-c2cnccn2)c2cc[nH]c2c1>>O=S(=O)(c1ccccc1)n1ccc2c(-c3cnccn3)cccc21 -US20080255078A1,3,CCC(=O)c1ccc(OC)c(OCCOCCO)c1.O=C(c1ccc(O)cc1)c1ccc(O)cc1>>CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(OC)c(OCCOCCO)c1 -US07199239B2,6,CCOC(=O)COc1ccc(CN(CCOC)c2cncc(-c3ccc(C(F)(F)F)cc3)n2)cc1C>>COCCN(Cc1ccc(OCC(=O)O)c(C)c1)c1cncc(-c2ccc(C(F)(F)F)cc2)n1 -US20150218169A1,1,O=C(O)C1CCNC1.O=C(c1c(Cl)cccc1C(F)(F)F)n1nc(Br)c2c(F)cccc21>>O=C(O)C1CCN(c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)C1 -US20070015788A1,6,CC(C)(C)OC(=O)N1CCC(n2cnc3cc(C#N)ccc32)CC1>>N#Cc1ccc2c(c1)ncn2C1CCNCC1 -US06953857B2,1,CI.COC(=O)c1cc(O)c(C)c(O)c1>>COC(=O)c1cc(O)c(C)c(OC)c1 -US06294531B1,1,C[O-].N#Cc1c(F)cccc1Cl>>COc1cccc(Cl)c1C#N -US07834019B2,8,COc1ccccc1-n1c(=O)c2cnc(SC)nc2n1C.O=C(OO)c1cccc(Cl)c1>>COc1ccccc1-n1c(=O)c2cnc(S(C)=O)nc2n1C -US20110086834A1,2,CC(=O)OC(C)=O.CC1C(=O)Nc2cc(Br)ccc21>>CC(=O)N1C(=O)C(C)c2ccc(Br)cc21 -US07951805B2,1,O=C(NCCC1CC1)c1ccc(Cl)nn1.O=C(c1ccc(F)cc1)C1CCNCC1>>O=C(NCCC1CC1)c1ccc(N2CCC(C(=O)c3ccc(F)cc3)CC2)nn1 -US04281183,2,COCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>COCCOS(=O)(=O)c1ccc(C)cc1 -US09040522B2,2,C1CC(N2CCOCC2)CN1.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)N3CCC(N4CCOCC4)C3)cn2)c1O -US20140371202A1,3,CC1(C)OB(c2ccc(OC3CCN(C=O)CC3)cc2)OC1(C)C.O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccsc1)N1CCCC1>>O=CN1CCC(Oc2ccc(-c3n[nH]c4ccc(NC(=O)C(c5ccsc5)N5CCCC5)cc34)cc2)CC1 -US20120302567A1,1,COc1cc(NC(=O)c2csc3c(SC)ncnc23)cc(OC)c1.COc1ccc(CCl)cc1>>COc1ccc(CN(C(=O)c2csc3c(SC)ncnc23)c2cc(OC)cc(OC)c2)cc1 -US08093385B2,7,COc1cc(-c2ccsc2)cc([N+](=O)[O-])c1>>COc1cc(N)cc(-c2ccsc2)c1 -US20060173075A1,1,CSc1ccc(N)cn1.O=Cc1ccc(F)cc1>>CSc1ccc(NCc2ccc(F)cc2)cn1 -US06500863B1,2,CC(C)(C)OC(=O)NCCN.O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)Cl)c1Cl>>CC(C)(C)OC(=O)NCCNS(=O)(=O)c1c(Cl)ccc([N+](=O)[O-])c1Cl -US20020087026A1,2,O=C(Cl)c1ccccc1.O=C(O)C(O)Cc1ccccc1>>O=C(OC(Cc1ccccc1)C(=O)O)c1ccccc1 -US20130178460A1,6,Cc1cc(NC(=O)c2csc3cnc(N[C@@H]4CCCC[C@@H]4NC(=O)OC(C)(C)C)nc23)cc2cccnc12>>Cc1cc(NC(=O)c2csc3cnc(N[C@@H]4CCCC[C@@H]4N)nc23)cc2cccnc12 -US20150057265A1,7,CC1CC(c2ccncc2N)=CC(O[Si](C)(C)C(C)(C)C)C1>>CC1CC(O[Si](C)(C)C(C)(C)C)CC(c2ccncc2N)C1 -US20070299068A1,2,CC(=O)Cl.CCn1c(-c2ccc(N)cc2)c(C#N)c2ccc(OC)cc21>>CCn1c(-c2ccc(NC(C)=O)cc2)c(C#N)c2ccc(OC)cc21 -US06528543B1,2,CO.CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1>>COC(=O)C(CC1CCCC1)c1ccc(S(C)(=O)=O)cc1 -US20040138286A1,6,CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc3[nH]ncc3c2)CC1>>O=C(NCC1CCNCC1)c1ccc2[nH]ncc2c1 -US20110160243A1,1,CCOC(=O)CC1CCCn2c1cc1cc(O)ccc12.CCOc1ccc(CCl)cc1OCC>>CCOC(=O)CC1CCCn2c1cc1cc(OCc3ccc(OCC)c(OCC)c3)ccc12 -US20140179702A1,2,CN.O=C(NC(Cc1ccccc1)C(O)C(=O)O)c1cccnc1-n1ccc(-c2ccccc2)n1>>CNC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1ccc(-c2ccccc2)n1 -US20090181971A1,7,COc1cccc(NC(=O)OC(C)(C)C)c1[N+](=O)[O-]>>COc1cccc(NC(=O)OC(C)(C)C)c1N -US08314100B2,1,C[O-].Nc1nc2cc(Cl)c(Cl)cc2nc1Cl>>COc1nc2cc(Cl)c(Cl)cc2nc1N -US08178490B2,3,C1CCNCC1.C=O.CCOC(=O)C(NC(C)=O)C(=O)OCC>>CCOC(=O)C(CN1CCCCC1)(NC(C)=O)C(=O)OCC -US08575393B2,7,O=C(O)C=Cc1cccc(C(F)(F)F)c1>>O=C(O)CCc1cccc(C(F)(F)F)c1 -US08680091B2,1,C1CCNCC1.N#Cc1ccc(C=O)cc1>>N#Cc1ccc(CN2CCCCC2)cc1 -US20130190289A1,6,COCCN1CC[C@H](N(C(=O)[C@@H]2CC[C@@H](C)CC2)c2cc(C#CC(C)(C)C)sc2C(=O)OC)C1=O>>COCCN1CC[C@H](N(C(=O)[C@@H]2CC[C@@H](C)CC2)c2cc(C#CC(C)(C)C)sc2C(=O)O)C1=O -US06403606B1,2,CCOC(=O)c1c(CN(CC)CC)nc2sc3c(c2c1-c1ccc(OC)c(OC)c1)CCNC3.O=C=Nc1ccccc1>>CCOC(=O)c1c(CN(CC)CC)nc2sc3c(c2c1-c1ccc(OC)c(OC)c1)CCN(C(=O)Nc1ccccc1)C3 -US05998433,2,O=C(O)c1ccc(C2(c3ccccc3)SCCS2)cc1.c1cc2c(o1)CNCC2>>O=C(c1ccc(C2(c3ccccc3)SCCS2)cc1)N1CCc2ccoc2C1 -US20140228361A1,1,COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1O.ClCCCN1CC2CCCC2C1>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CC2CCCC2C1 -US08754071B2,1,C1CNC1.Cc1ccc(-c2noc(Cl)n2)cc1[N+](=O)[O-]>>Cc1ccc(-c2noc(N3CCC3)n2)cc1[N+](=O)[O-] -US20120053171A1,2,CCOC(=O)CCCC(NNC(=O)OC(C)(C)C)c1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)NN1C(=O)CCCC1c1cccc(C(F)(F)F)c1 -US20040058939A1,6,O=C1NCC(OC2CCCCO2)c2cc3cccnc3n21>>O=C1NCC(O)c2cc3cccnc3n21 -US08329729B2,1,O=C(CBr)Nc1cccc(F)c1.O=C(O[C@H]1CN2CCC1CC2)C1(c2cccs2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3cccs3)CCCCCC1)C2)Nc1cccc(F)c1 -US07179823B1,1,CCOC(=O)CCc1c[nH]nc1-c1ccccc1.ClCc1ccc(OCc2ccc3ccccc3n2)nc1>>CCOC(=O)CCc1cn(Cc2ccc(OCc3ccc4ccccc4n3)nc2)nc1-c1ccccc1 -US20040214808A1,7,COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(CCC#N)CC3)cc1>>COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(CCCN)CC3)cc1 -US08586620B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNC1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1>>CCN(C(=O)OC(C)(C)C)C1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1 -US09012651B2,1,CC(C)[C@@H](N)CO.O=Cc1nc(Br)ccc1F>>CC(C)[C@H](CO)NCc1nc(Br)ccc1F -US08835428B2,9,NO.O=Cc1ccc(OCc2ccccc2)cc1>>O/N=C\c1ccc(OCc2ccccc2)cc1 -US20130231335A1,1,CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C(C)C.NCCN>>CC[C@@H]1C(=O)N(C)c2cnc(NCCN)nc2N1C(C)C -US20060041146A1,2,C[C@@H](CC(=O)O)c1ccccc1.O=C1N[C@@H](c2ccccc2)CO1>>C[C@@H](CC(=O)N1C(=O)OC[C@@H]1c1ccccc1)c1ccccc1 -US04359578,1,C=O.CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)nc21 -US20100272680A1,1,CC1CN(C(=O)OC(C)(C)C)CCC1=O.NCCO>>CC1CN(C(=O)OC(C)(C)C)CCC1NCCO -US07879844B2,6,NC(=O)C12CC3CC(C1)C(Nc1c(C(=O)OCc4ccccc4)cnc4[nH]ccc14)C(C3)C2>>NC(=O)C12CC3CC(C1)C(Nc1c(C(=O)O)cnc4[nH]ccc14)C(C3)C2 -US05627189,1,BrCCCBr.Oc1ccccc1C(F)(F)F>>FC(F)(F)c1ccccc1OCCCBr -US05519048,6,CCOC(=O)c1c(/C=C(\C(=O)OC(C)(C)C)c2ccc(OC)cc2)c2c(Cl)cc(Cl)cc2n1S(=O)(=O)c1ccc(C)cc1>>CCOC(=O)c1c(/C=C(\C(=O)O)c2ccc(OC)cc2)c2c(Cl)cc(Cl)cc2n1S(=O)(=O)c1ccc(C)cc1 -US20090312342A1,2,CC(C)C[C@@H](O)C(=O)O.Cc1ccc2c(N3CCNCC3CO)nc(-c3ccccc3O)nc2c1>>Cc1ccc2c(N3CCN(C(=O)[C@H](O)CC(C)C)CC3CO)nc(-c3ccccc3O)nc2c1 -US06350907B1,7,Cc1cc([N+](=O)[O-])ccc1-c1ccc(C#N)cc1>>Cc1cc(N)ccc1-c1ccc(C#N)cc1 -US20080146806A1,6,CCNC(=O)CN1CC[C@H]2C[C@@H](C(=O)OCC)N(S(=O)(=O)c3ccc(OC)cc3)[C@H]2C1>>CCNC(=O)CN1CC[C@H]2C[C@@H](C(=O)O)N(S(=O)(=O)c3ccc(OC)cc3)[C@H]2C1 -US20140323480A1,1,C[O-].Cc1c(Cn2cnc3c(Cl)cc(Cl)nc32)cccc1C(F)(F)F>>COc1cc(Cl)nc2c1ncn2Cc1cccc(C(F)(F)F)c1C -US20090281092A1,2,C1CN(CC2CC2)CCN1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)N2CCN(CC3CC3)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20130166268A1,7,CC(C)Oc1ccc(S(N)(=O)=O)cc1[N+](=O)[O-]>>CC(C)Oc1ccc(S(N)(=O)=O)cc1N -US20110118262A1,2,COC(=O)c1ccc(C2CCNC2)c(C(F)(F)F)c1.O=C(O)c1ccc[nH]1>>COC(=O)c1ccc(C2CCN(C(=O)c3ccc[nH]3)C2)c(C(F)(F)F)c1 -US20080176857A1,2,CCc1cc2c(N3CCNCC3)nc(SCC(=O)OC)nc2s1.COc1ccc(-c2noc(C)c2C(=O)O)cc1>>CCc1cc2c(N3CCN(C(=O)c4c(-c5ccc(OC)cc5)noc4C)CC3)nc(SCC(=O)OC)nc2s1 -US06780996B2,1,COCCO.COc1cc2c(=O)c(C#N)c[nH]c2cc1F>>COCCOc1cc2[nH]cc(C#N)c(=O)c2cc1OC -US20090124598A1,2,CNCc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1.COc1cc(OC)cc(C(=O)Cl)c1>>COc1cc(OC)cc(C(=O)N(C)Cc2ccc(C(=O)N3CC4(C)CC3CC(C)(C)C4)cc2)c1 -US20120165310A1,1,OC[C@@H]1CCCO1.Oc1cccc(Br)c1>>Brc1cccc(OC[C@@H]2CCCO2)c1 -US20090042874A1,1,CCOP(OCC)OCC.COc1c(Cl)cc(CBr)c(F)c1[N+](=O)[O-]>>CCOP(=O)(Cc1cc(Cl)c(OC)c([N+](=O)[O-])c1F)OCC -US20120115869A1,1,CCC(=O)Nc1cccc(C#N)c1.Fc1ccc(CBr)cc1>>CCC(=O)N(Cc1ccc(F)cc1)c1cccc(C#N)c1 -US20150141398A1,1,CC(C)(C)OC(=O)N1CCC(c2ccc(NC(=O)C3CNC3)cc2)CC1.Clc1ccc(Cl)nn1>>CC(C)(C)OC(=O)N1CCC(c2ccc(NC(=O)C3CN(c4ccc(Cl)nn4)C3)cc2)CC1 -US08354399B2,6,CCOC(=O)N1CCC(N(C(=O)C(F)(F)F)c2cc(N3CCN(C)CC3)ccc2C(=O)OC(C)(C)C)CC1>>CCOC(=O)N1CCC(N(C(=O)C(F)(F)F)c2cc(N3CCN(C)CC3)ccc2C(=O)O)CC1 -US06440972B1,2,O=C(C1CCN(c2ccncc2F)CC1)N1CCNCC1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=C(C1CCN(c2ccncc2F)CC1)N1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 -US20100197700A1,6,CC(C)(C)OC(=O)N1CCC(CC#N)CC1>>N#CCC1CCNCC1 -US20130005744A1,6,CC(C)n1cc(-c2ccc(Cl)c(C(F)(F)F)c2)cc(OCc2ccccc2)c1=O>>CC(C)n1cc(-c2ccc(Cl)c(C(F)(F)F)c2)cc(O)c1=O -US20100152219A1,1,CC(C)c1cc(N)[nH]n1.Clc1ncc(Cl)c(Cl)n1>>CC(C)c1cc(Nc2nc(Cl)ncc2Cl)[nH]n1 -US20150266857A1,6,CC(C)(C)OC(=O)NCc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2[nH]1>>NCc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2[nH]1 -US20130338196A1,9,CC(C)(C)[Si](C)(C)OC(c1ncc(C(N)=O)o1)C1CCc2cc(Oc3ccccc3)ccc2C1>>CC(C)(C)[Si](C)(C)OC(c1ncc(C#N)o1)C1CCc2cc(Oc3ccccc3)ccc2C1 -US20070123573A1,6,Nc1nc2c(s1)CC(N1C(=O)c3ccccc3C1=O)CC2>>Nc1nc2c(s1)CC(N)CC2 -US20100075990A1,1,Brc1cccnc1.c1ccc(-c2ncc(-c3c[nH]c(C4CCNCC4)n3)cn2)cc1>>c1ccc(-c2ncc(-c3c[nH]c(C4CCN(c5cccnc5)CC4)n3)cn2)cc1 -US07037880B2,1,CCOCCl.Cn1nc(C(F)(F)F)c(C(O)=C(C#N)c2coc(C(C)(C)C)n2)c1Cl>>CCOCOC(=C(C#N)c1coc(C(C)(C)C)n1)c1c(C(F)(F)F)nn(C)c1Cl -US05500417,1,COP(OC)OC.Clc1ccccc1CBr>>COP(=O)(Cc1ccccc1Cl)OC -US06395733B1,1,Cc1cccc(N)c1.Clc1ncnc2[nH]ccc12>>Cc1cccc(Nc2ncnc3[nH]ccc23)c1 -US20110251184A1,2,C#CCN.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>C#CCNS(=O)(=O)c1ccccc1[N+](=O)[O-] -US05883255,6,CCC(=O)c1cc2n(c(=O)c1C)Cc1c-2nc2ccccc2c1COC(=O)CNC(=O)OC(C)(C)C>>CCC(=O)c1cc2n(c(=O)c1C)Cc1c-2nc2ccccc2c1COC(=O)CN -US06211198B1,7,N#CCCN1CCC(C(c2ccccc2)c2ccccc2)CC1>>NCCCN1CCC(C(c2ccccc2)c2ccccc2)CC1 -US20150099737A1,2,CC(C)(C)OC(=O)N1C2CCNCC1CC2.CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)O)cn3)nc2n1C1CCCC1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CCC5CCC(C4)N5C(=O)OC(C)(C)C)cn3)nc2n1C1CCCC1 -US20150119373A1,1,C=C(C)[C@@H]1CC[C@]2(c3nnc(-c4ccccc4)o3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.COC(=O)C[C@@H]1[C@H](C(=O)O)C1(C)C>>C=C(C)[C@@H]1CC[C@]2(c3nnc(-c4ccccc4)o3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)[C@H]6[C@@H](CC(=O)OC)C6(C)C)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20110092461A1,2,CC(C)(C)OC(=O)N1CCN(Cc2ccc(C(=O)O)cc2)C(=O)C1.Nc1ccc(Cl)c(-c2ccccn2)c1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cc2)C(=O)C1 -US07256198B2,6,CC1(C)CN=C2N(C1)c1ccc(NS(=O)(=O)c3ccccc3)cc1C21OCCCO1>>CC1(C)CN=C2C(=O)c3cc(NS(=O)(=O)c4ccccc4)ccc3N2C1 -US09096600B2,1,Brc1ncnc2[nH]cnc12.CC(=O)Nc1c(C)c(Cl)cc(C(C)N)c1-c1cccc(F)c1>>CC(=O)Nc1c(C)c(Cl)cc(C(C)Nc2ncnc3[nH]cnc23)c1-c1cccc(F)c1 -US20090105484A1,3,Brc1ccc(C2=NO[C@@H](CN3CCOCC3)C2)nc1.CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C>>O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NO[C@@H](CN4CCOCC4)C3)nc2)c(F)c1 -US07271197B2,9,BrC(Br)(Br)Br.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)S(=O)(=O)c1cccc(CO)c1>>C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)S(=O)(=O)c1cccc(CBr)c1 -US09155727B2,2,CC(C)(C)C(=O)OC(=O)C(C)(C)C.NNC(=O)c1nc(Br)cnc1N>>CC(C)(C)C(=O)NNC(=O)c1nc(Br)cnc1N -US08895745B2,3,CC1(C)OB(c2ccn3ccnc3c2)OC1(C)C.COC(=O)c1ccc(Br)cn1>>COC(=O)c1ccc(-c2ccn3ccnc3c2)cn1 -US20070082880A1,1,CN1CCNCC1.N#Cc1cnc2sc(-c3cccc(C=O)c3)cc2c1Nc1ccc2[nH]ccc2c1>>CN1CCN(Cc2cccc(-c3cc4c(Nc5ccc6[nH]ccc6c5)c(C#N)cnc4s3)c2)CC1 -US20050234081A1,1,COC(=O)c1cc(Br)c([N+](=O)[O-])s1.Sc1ccc2ccccc2c1>>COC(=O)c1cc(Sc2ccc3ccccc3c2)c([N+](=O)[O-])s1 -US04952587,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CC2CCC1NC2>>COC(=O)C1CC2CCC1N(C(=O)OC(C)(C)C)C2 -US20110207698A1,1,ClCc1csc(-c2ccc(Cl)cc2)n1.N#Cc1c(N)nc(S)c(C#N)c1-c1cscn1>>N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cscn1 -US05302718,2,Cc1cccnc1N.O=S(=O)(Cl)c1cccc(I)c1>>Cc1cccnc1NS(=O)(=O)c1cccc(I)c1 -US20120289522A1,3,C=CCC(O)c1c(C)noc1-c1ccc(-c2ccc(C3(C(=O)OCC)CC3)cc2)cc1.FC(F)(F)c1ccccc1I>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C/C=C/c4ccccc4C(F)(F)F)cc3)cc2)CC1 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2ccc(Cl)c(C(F)(F)F)c2)cc1.O=C(O)c1cc(Cl)cc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccc(Cl)c(C(F)(F)F)c2)C(=O)c2cc(Cl)cc3cc[nH]c23)cc1 -US20050032786A1,6,CC(C)(C)OC(=O)NCCc1ccnc(-c2nc(=O)c3ccccc3s2)c1>>NCCc1ccnc(-c2nc(=O)c3ccccc3s2)c1 -US20080108557A1,2,CC(C)(C)OC(=O)NOCCCCN.Cc1cc(=O)oc2cc(OCC(=O)O)ccc12>>Cc1cc(=O)oc2cc(OCC(=O)NCCCCONC(=O)OC(C)(C)C)ccc12 -US08278325B2,1,CCCCOC(=O)c1nc(Cl)c2ccccc2c1O.Oc1ccc(F)cc1>>CCCCOC(=O)c1nc(Oc2ccc(F)cc2)c2ccccc2c1O -US06693101B2,3,COc1ccc(CNc2cccc(CCCCC(=O)CP(=O)(OC)OC)n2)cc1.Cc1ncc(C=O)cn1>>COc1ccc(CNc2cccc(CCCCC(=O)C=Cc3cnc(C)nc3)n2)cc1 -US20090275578A1,1,C#CCBr.O=C1NCc2ccccc21>>C#CCN1Cc2ccccc2C1=O -US08344135B2,1,C1CSCCN1.CN(c1cccc(NC(=O)c2cccc(C(C)(C)C#N)c2)c1)c1ncc2nc(NC(=O)CCl)sc2n1>>CN(c1cccc(NC(=O)c2cccc(C(C)(C)C#N)c2)c1)c1ncc2nc(NC(=O)CN3CCSCC3)sc2n1 -US07858796B2,3,CN(C)CCCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1.OCc1cccc(B(O)O)c1>>CN(C)CCCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CO)c4)cc23)CC1 -US20140357713A1,1,CC(C)N.CCCCCCCCCCCCOC(=O)C(C)Br>>CCCCCCCCCCCCOC(=O)C(C)NC(C)C -US05576313,2,CS(=O)(=O)Cl.Cc1ccccc1CC1(N)CCN(C(=O)OC(C)(C)C)CC1>>Cc1ccccc1CC1(NS(C)(=O)=O)CCN(C(=O)OC(C)(C)C)CC1 -US05606089,6,CC(=O)Oc1c(C(C)(C)C)cc2c(c1C(C)(C)C)CC(CCC(C)C)(CCC(C)C)O2>>CC(C)CCC1(CCC(C)C)Cc2c(cc(C(C)(C)C)c(O)c2C(C)(C)C)O1 -US20020177578A1,9,CC(=O)O[C@@H]1[C@H](OC(C)=O)[C@H](C)O[C@H](N=[N+]=[N-])[C@H]1OC(C)=O>>CC(=O)O[C@@H]1[C@H](OC(C)=O)[C@H](C)O[C@H](N)[C@H]1OC(C)=O -US06316632B1,3,Nc1cccnc1Cl.OB(O)c1ccccc1>>Nc1cccnc1-c1ccccc1 -US06143764,1,COc1cc2nccc(Cl)c2cc1OC.O=C(c1ccc(O)cc1)c1ccc(Cl)c(Cl)c1>>COc1cc2nccc(Oc3ccc(C(=O)c4ccc(Cl)c(Cl)c4)cc3)c2cc1OC -US05457106,2,CCCCC(CC)C(=O)Cl.NCCCSc1ccncc1>>CCCCC(CC)C(=O)NCCCSc1ccncc1 -US20140243336A1,1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1cnc(C#N)c(Br)c1.Cc1nc(N)ccc1C#N>>Cc1nc(Nc2cc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)cnc2C#N)ccc1C#N -US20110144068A1,1,CC(=O)c1c[nH]nc1-c1cccc([N+](=O)[O-])c1.COc1ccc(CCl)cc1>>COc1ccc(Cn2cc(C(C)=O)c(-c3cccc([N+](=O)[O-])c3)n2)cc1 -US20150183763A1,10,COC(=O)/C=C(/C)C(=O)OC.O=C1CCC(=O)N1Br>>COC(=O)/C=C(\CBr)C(=O)OC -US08063061B2,3,C[Mg+].Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4csc(C=O)n4)ccc3n(C)c21>>CC(O)c1nc(-c2ccc3c(c2)c2cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c2n3C)cs1 -US05932590,6,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCc1cncn1Cc1ccc(C#N)cc1>>N#Cc1ccc(Cn2cncc2CCNC(=O)[C@@H]2Cc3ccccc3CN2)cc1 -US20130079320A1,2,CC(C(=O)O)c1ccc(C#N)cc1.NCc1ccc(C(F)(F)F)nc1N1CCCC1>>CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCC1)c1ccc(C#N)cc1 -US20120282629A1,1,NNc1ccc([N+](=O)[O-])cc1.O=Cc1cc(O)c(O)cc1O>>O=[N+]([O-])c1ccc(NN=Cc2cc(O)c(O)cc2O)cc1 -US08895313B2,3,CCOP(=O)(Cc1ccc(-c2nc3ccc(C)cc3s2)cc1)OCC.O=Cc1ccc(O)cc1>>Cc1ccc2nc(-c3ccc(/C=C/c4ccc(O)cc4)cc3)sc2c1 -US20150111887A1,1,CC(C)(C)[S@@](N)=O.Cn1cc(-c2cc3c(N4CCN(c5ncc(C(=O)c6ccc(F)cc6)cn5)CC4)ncnn3c2)cn1>>Cn1cc(-c2cc3c(N4CCN(c5ncc(/C(=N\[S@@](=O)C(C)(C)C)c6ccc(F)cc6)cn5)CC4)ncnn3c2)cn1 -US06927228B2,3,CCOC(=O)CC(=O)OCC.CN(Cc1cccc(-c2ccc(C=O)cc2)c1)C(=O)c1ccccc1>>CCOC(=O)C(=Cc1ccc(-c2cccc(CN(C)C(=O)c3ccccc3)c2)cc1)C(=O)OCC -US07659286B2,2,CC(C)(C)OC(=O)N1CCC(=C(Br)c2ccc(C(=O)O)cc2)CC1.CNCCO>>CN(CCO)C(=O)c1ccc(C(Br)=C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US08097733B2,7,O=C(O)c1cccc(Br)c1F>>OCc1cccc(Br)c1F -US20120316147A1,6,COC(=O)c1ccc(C2CC2)c(-c2cccc(Cl)c2)n1>>O=C(O)c1ccc(C2CC2)c(-c2cccc(Cl)c2)n1 -US06093732,7,O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)cc(C#CCCCO)cc2c1O>>O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)cc(CCCCCO)cc2c1O -US20110237517A1,6,CNC(C)C(=O)NC(C(=O)N1CCC2C1CCN2C(=O)OCc1ccccc1)C1CCCCC1>>CNC(C)C(=O)NC(C(=O)N1CCC2NCCC21)C1CCCCC1 -US20150045368A1,3,CC1(C)OB(c2cnc3[nH]ccc3c2)OC1(C)C.CC1(C)OC(=O)N(C2CC=C(OS(=O)(=O)C(F)(F)F)CC2)[C@H]1c1ccccc1>>CC1(C)OC(=O)N(C2CC=C(c3cnc4[nH]ccc4c3)CC2)[C@H]1c1ccccc1 -US20150150845A1,1,CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21.OCCBr>>CC1(C)c2cc(OCCBr)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 -US07094798B1,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O.O=C1NC(=O)c2c1c(I)cc1[nH]c3ccc(O)cc3c21>>COc1cc(-c2cc3[nH]c4ccc(O)cc4c3c3c2C(=O)NC3=O)ccc1O -US20090036495A1,1,COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2O)cc1.COC(C)(C)CCO>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2OCCC(C)(C)OC)cc1 -US20120214735A1,1,CCOC(=O)C(Br)c1ccc(S(=O)(=O)C2CC2)cc1.Nc1ccc(F)cc1F>>CCOC(=O)C(Nc1ccc(F)cc1F)c1ccc(S(=O)(=O)C2CC2)cc1 -US20100075968A1,1,CN1C(=O)NCC1C(=O)NCc1ccc(F)c(F)c1Cl.ClCCN1CCOCC1>>CN1C(=O)N(CCN2CCOCC2)CC1C(=O)NCc1ccc(F)c(F)c1Cl -US20110319378A1,1,CC[C@@H]([C@H](C)O)N1C(=O)[C@@](C)(CC(=O)OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1.CI>>CC[C@@H]([C@H](C)OC)N1C(=O)[C@@](C)(CC(=O)OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US08791108B2,6,CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(-c3ccc4c(c3Cl)NCCO4)n2n1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C(=O)O)nn2c1-c1ccc2c(c1Cl)NCCO2 -US20140171430A1,2,COc1ccc(C(=O)O)c(C)c1.c1ccc2nc(N3CC4CNCC4C3)cnc2c1>>COc1ccc(C(=O)N2CC3CN(c4cnc5ccccc5n4)CC3C2)c(C)c1 -US20060142262A1,1,CC(C)c1noc(N2CCC(O)CC2)n1.CS(=O)(=O)c1ccc(-n2ncc3c(Cl)ncnc32)c(F)c1>>CC(C)c1noc(N2CCC(Oc3ncnc4c3cnn4-c3ccc(S(C)(=O)=O)cc3F)CC2)n1 -US20070032485A1,1,CCOC(=O)N1c2ccc(OC)nc2[C@@H](N)C[C@H]1CC.O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC -US20050250797A1,1,COc1cc2c(Cl)ncnc2cc1O.OCCCN1CCN(CCF)CC1>>COc1cc2c(Cl)ncnc2cc1OCCCN1CCN(CCF)CC1 -US04199519,2,C/C(=C/C(=O)O)CC/C=C(\C)CO.CCNCC>>CCN(CC)C(=O)/C=C(/C)CC/C=C(\C)CO -US07067534B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.O=S(=O)(Cl)c1cc(Cl)ccc1Cl>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](NS(=O)(=O)c3cc(Cl)ccc3Cl)c3ccccc3)CC2)c1 -US05110818,1,NCc1ccccc1F.Nc1cnc(Cl)nc1Cl>>Nc1cnc(Cl)nc1NCc1ccccc1F -US20130244999A1,3,CC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1.CN1CCN(c2cc(N3CCc4ccc(Br)cc4C3)nc(N)n2)CC1>>CC(=O)Nc1ccc(-c2ccc3c(c2)CN(c2cc(N4CCN(C)CC4)nc(N)n2)CC3)cn1 -US20070185107A1,2,COc1cc2c(c(N3CCN(C)CC3)c1)OC(C(=O)O)CC2.CS(=O)(=O)N1CCN(c2ccc(N)cc2)CC1>>COc1cc2c(c(N3CCN(C)CC3)c1)OC(C(=O)Nc1ccc(N3CCN(S(C)(=O)=O)CC3)cc1)CC2 -US20030153536A1,6,COC(=O)CCCOc1c(C(C)(C)C)cc(SC(C)(C)Sc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1C(C)(C)C>>CC(C)(Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Sc1cc(C(C)(C)C)c(OCCCC(=O)O)c(C(C)(C)C)c1 -US20050143381A1,1,O=c1n(Cc2ccc(-c3ccno3)cc2)nc2c(Cl)c(-c3ccc(Cl)cc3)cnn12.c1c[nH]cn1>>O=c1n(Cc2ccc(-c3ccno3)cc2)nc2c(-n3ccnc3)c(-c3ccc(Cl)cc3)cnn12 -US06887875B2,3,CCc1nc(-c2ccc(OC)cc2OC)c(CC)nc1Cl.Cc1ccc(C)c(B(O)O)c1>>CCc1nc(-c2ccc(OC)cc2OC)c(CC)nc1-c1cc(C)ccc1C -US20140058098A1,2,CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(N3CCN(CC(=O)O)CC3)nc1OCC2.CN>>CNC(=O)CN1CCN(c2ccc3c(n2)OCCn2cc(-c4ncnn4C(C)C)nc2-3)CC1 -US08796280B2,1,O=S(=O)(Nc1nccnc1-c1ccc(CCl)cc1)c1ccccc1Cl.c1ccc2[nH]ccc2c1>>O=S(=O)(Nc1nccnc1-c1ccc(Cn2ccc3ccccc32)cc1)c1ccccc1Cl -US06924276B2,2,Cc1sc(C(=O)OCc2ccccc2)cc1N.O=C(Cl)Cc1ccccc1>>Cc1sc(C(=O)OCc2ccccc2)cc1NC(=O)Cc1ccccc1 -US05767268,6,CC(=O)OC[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C(=O)NC[C@H]1O[C@@](O)(Cc2ccccc2)[C@H](NC(=O)OCc2ccccc2)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C(=O)NC[C@H]1O[C@@](O)(Cc2ccccc2)[C@H](N)[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US08927531B2,1,C1CC2CCC(C1)N2.COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C(F)(F)F)c4CBr)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C(F)(F)F)c4CN3C4CCCC3CC4)ccc21 -US20140178304A1,1,O=c1c(O)cn(-c2ccc(C3CCOCC3)cc2F)nc1-c1ccnn1-c1ccccc1.OCCF>>O=c1c(OCCF)cn(-c2ccc(C3CCOCC3)cc2F)nc1-c1ccnn1-c1ccccc1 -US20150259323A1,2,CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)O)cn2)C1.COC(=O)c1cccc(CN)c1>>CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)NCc3cccc(C(=O)OC)c3)cn2)C1 -US06900209B2,1,Cc1cc(-c2nnc3c4ccccc4c(Cl)nn23)no1.Cn1nnc(CO)c1CCN1CCC1>>Cc1cc(-c2nnc3c4ccccc4c(OCc4nnn(C)c4CCN4CCC4)nn23)no1 -US20080045506A1,1,BrCC1CC1.CC(C)(C)OC(=O)N1CCCNCC1>>CC(C)(C)OC(=O)N1CCCN(CC2CC2)CC1 -US08293902B2,1,CC(=O)N1CCNCC1.OCCCBr>>CC(=O)N1CCN(CCCO)CC1 -US20020188009A1,1,BrCCCCCBr.Cc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>Cc1nc(-c2ccccc2)c(-c2ccccc2)n1CCCCCBr -US20060014945A1,7,CC1(C)CCNC(=O)[C@H](N(Cc2ccc(C(=O)O)cc2F)S(=O)(=O)c2ccc(Cl)cc2)C1>>CC1(C)CCNC(=O)[C@H](N(Cc2ccc(CO)cc2F)S(=O)(=O)c2ccc(Cl)cc2)C1 -US05972937,2,CSc1cc2c(cc1C(F)(F)F)NCC2.O=C=Nc1ccccc1>>CSc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccccc1)CC2 -US20140140956A1,1,C=O.COc1cc(F)cc2nc(-c3ccc(OC4CNC4)c(-c4ccc(S(C)=O)cc4)c3)[nH]c(=O)c12>>COc1cc(F)cc2nc(-c3ccc(OC4CN(C)C4)c(-c4ccc(S(C)=O)cc4)c3)[nH]c(=O)c12 -US08765744B2,5,C=CCC1(N)CCC2(CC1)OCCO2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C=CCC1(NC(=O)C(F)(F)F)CCC2(CC1)OCCO2 -US07064124B2,7,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccc(OC)c(OC)c3)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)Nc3ccc(OC)c(OC)c3)c2)=C(C)C1=O -US20060205787A1,2,C[C@]1(N2C(=O)c3cccc(N)c3C2=O)CCC(=O)NC1=O.O=C(Cl)CCl>>C[C@]1(N2C(=O)c3cccc(NC(=O)CCl)c3C2=O)CCC(=O)NC1=O -US20080287399A1,1,COc1ccc(CNc2nc(Cl)ccc2[N+](=O)[O-])cc1.Oc1ccccc1>>COc1ccc(CNc2nc(Oc3ccccc3)ccc2[N+](=O)[O-])cc1 -US20090197883A1,8,CC1CC(c2ccccc2)(c2cc(OCc3ccc4cc(F)ccc4n3)ccc2C(C)O)C1>>CC(=O)c1ccc(OCc2ccc3cc(F)ccc3n2)cc1C1(c2ccccc2)CC(C)C1 -US09096592B2,2,N#Cc1cncnc1N.O=C(O)c1nn(Cc2ccccc2F)c2ncccc12>>N#Cc1cncnc1NC(=O)c1nn(Cc2ccccc2F)c2ncccc12 -US20110136763A1,7,CCOC(=O)C(C)C1OB(O)c2cc(Oc3nnc([N+](=O)[O-])s3)cc(C)c21>>CCOC(=O)C(C)C1OB(O)c2cc(Oc3nnc(N)s3)cc(C)c21 -US05604229,3,CCCCCCCBr.O=Cc1ccccc1Br>>CCCCCCCC(O)c1ccccc1Br -US05006556,1,C#CCBr.OCCc1ccccc1>>C#CCOCCc1ccccc1 -US08729274B2,7,C=Cc1ccc2c(c1Cl)CC[C@]1(C)CN(Cc3ccccc3)C[C@@H]21>>CCc1ccc2c(c1Cl)CC[C@]1(C)CN(Cc3ccccc3)C[C@@H]21 -US20060004197A1,1,Cc1ccc(S(=O)(=O)Nc2cc(F)c([N+](=O)[O-])cc2NS(=O)(=O)c2ccc(C)cc2)cc1.SCc1ccccc1Cl>>Cc1ccc(S(=O)(=O)Nc2cc(SCc3ccccc3Cl)c([N+](=O)[O-])cc2NS(=O)(=O)c2ccc(C)cc2)cc1 -US07220865B2,1,CCC[C@H](N)C(=O)Nc1cc(CC2CCCC2)on1.O=C1CCc2cc(F)ccc2C1>>CCC[C@H](NC1CCc2cc(F)ccc2C1)C(=O)Nc1cc(CC2CCCC2)on1 -US20150051197A1,1,O=C(NCCCCl)Nc1ccc(Oc2ccc(Cl)cc2)cc1>>O=C1NCCCN1c1ccc(Oc2ccc(Cl)cc2)cc1 -US20050245543A1,3,COc1ncc(B(O)O)c(OC)n1.C[C@H](c1ccc(-c2ccc(Br)cc2)cc1)N1CCCC1>>COc1ncc(-c2ccc(-c3ccc([C@@H](C)N4CCCC4)cc3)cc2)c(OC)n1 -US20130109046A1,9,CCOc1nc(C2CC2)c(C=O)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1F.NO>>CCOc1nc(C2CC2)c(C=NO)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1F -US20090099158A1,1,CC(C)=O.COC(=O)C1CCNCC1>>COC(=O)C1CCN(C(C)C)CC1 -US20060178382A1,4,C#CC(=O)O.CCOC(=O)CN=[N+]=[N-]>>CCOC(=O)Cn1cc(C(=O)O)nn1 -US08921082B2,7,O=C[C@H](O)[C@@H](O)[C@H](O)CO>>OC[C@H](O)[C@@H](O)[C@H](O)CO -US20100331306A1,3,CC(c1nc2ccc(F)cc2c(Cl)c1-c1ccccc1)N1C(=O)c2ccccc2C1=O.CCCC[Sn](C#N)(CCCC)CCCC>>CC(c1nc2ccc(F)cc2c(C#N)c1-c1ccccc1)N1C(=O)c2ccccc2C1=O -US06900215B2,3,CC(C)(F)c1ccn2c(Br)cnc2n1.CC1(C)OB(c2ccc(F)c(-c3ccccc3C#N)c2)OC1(C)C>>CC(C)(F)c1ccn2c(-c3ccc(F)c(-c4ccccc4C#N)c3)cnc2n1 -US20090018134A1,2,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C3CCCC3)CC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)C3CCCC3)CC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US06133303,3,O=C1CCCc2cc(OCCn3ccnc3)ccc21.O=Cc1nccs1>>O=C1c2ccc(OCCn3ccnc3)cc2CCC1C(O)c1nccs1 -US20120101082A1,6,COC(=O)c1ccc(OCCCC(=O)OC(C)(C)C)c(C)c1>>Cc1cc(C(=O)O)ccc1OCCCC(=O)OC(C)(C)C -US20140350019A1,2,Nc1c(F)ccc(O)c1F.O=C(O)c1cccc(-c2cccc(F)c2)c1>>O=C(Nc1c(F)ccc(O)c1F)c1cccc(-c2cccc(F)c2)c1 -US20130144067A1,1,COC(=O)[C@@H](N)C(C)C.N#Cc1ccccc1-c1ccc(CBr)cc1>>COC(=O)[C@@H](NCc1ccc(-c2ccccc2C#N)cc1)C(C)C -US08513252B2,6,CCOC(=O)c1cn(Cc2ccc(OC)cc2)nc1C>>COc1ccc(Cn2cc(C(=O)O)c(C)n2)cc1 -US20100204212A1,9,CC(C)(C)OC(=O)Nc1ccc(Nc2cc(Cl)nn3ccnc23)cc1>>CC(C)(C)OC(=O)Nc1ccc(Nc2ccnn3ccnc23)cc1 -US20140171430A1,2,O=C(O)c1ccccc1-c1cccs1.c1ccc(-c2ccnc(N3CC4CNCC4C3)n2)cc1>>O=C(c1ccccc1-c1cccs1)N1CC2CN(c3nccc(-c4ccccc4)n3)CC2C1 -US20070129345A1,1,N#Cc1ccc(F)cc1.O=C1N([C@@H]2CC[C@@H](O)CC2)CCC12CCNCC2>>N#Cc1ccc(N2CCC3(CC2)CCN([C@@H]2CC[C@@H](O)CC2)C3=O)cc1 -US04558134,1,CCSc1cc(C#N)c(Cl)cn1.Oc1ccc(Cl)c(Cl)c1>>CCSc1cc(C#N)c(Oc2ccc(Cl)c(Cl)c2)cn1 -US20100298285A1,1,CC(Br)c1ccc(F)cc1.O=C(Cc1ccc(C(F)(F)F)c(F)c1)Nc1cccc2c1CCNC2>>CC(c1ccc(F)cc1)N1CCc2c(cccc2NC(=O)Cc2ccc(C(F)(F)F)c(F)c2)C1 -US20150203486A1,1,COC(=O)C1C2CCC1CNC2.OB(O)c1cnc(Cl)nc1>>COC(=O)C1[C@H]2CC[C@@H]1CN(c1ncc(B(O)O)cn1)C2 -US20090062307A1,3,CCn1c(-c2nc(Br)cnc2N)nc2cnccc21.OB(O)c1ccccc1>>CCn1c(-c2nc(-c3ccccc3)cnc2N)nc2cnccc21 -US20130005743A1,2,Cc1ccc(-n2nc(C)c3c(C(=O)O)cc(C)nc32)cn1.Cc1ccnc(C)c1N>>Cc1ccc(-n2nc(C)c3c(C(=O)Nc4c(C)ccnc4C)cc(C)nc32)cn1 -US20120214798A1,1,OC(CN1CCC(N2CCCCC2)CC1)c1ccccc1.c1cn(CCN2CCNCC2)cn1>>c1ccc(C(CN2CCC(N3CCCCC3)CC2)N2CCN(CCn3ccnc3)CC2)cc1 -US07053245B2,7,O=[N+]([O-])c1ccc(OCc2cccc(F)c2)cc1>>Nc1ccc(OCc2cccc(F)c2)cc1 -US20050043368A1,8,CCCC[C@H](NC(=O)O[C@H](Cn1ccc(-c2ccc(C(F)(F)F)cc2)n1)C(C)(C)C)[C@H](O)CNC(=O)N1CCOCC1>>CCCC[C@H](NC(=O)O[C@H](Cn1ccc(-c2ccc(C(F)(F)F)cc2)n1)C(C)(C)C)C(=O)CNC(=O)N1CCOCC1 -US20120028919A1,3,COCc1ccccc1B(O)O.COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc2ccc(Br)n2n1>>COCc1ccccc1-c1ccc2cnc(Nc3ccc(N4CCC(N5CCN(C)CC5)CC4)cc3OC)nn12 -US05338856,6,CCOC(=O)c1c(C(F)(F)F)nsc1SC>>CSc1snc(C(F)(F)F)c1C(=O)O -US20030199520A1,8,CC(C)(C)OC(=O)n1ccc2cc(CO)ccc21>>CC(C)(C)OC(=O)n1ccc2cc(C=O)ccc21 -US05371064,8,O=C(OO)c1cccc(Cl)c1.O=C(c1ccc(C(F)(F)F)cc1Sc1ccc(Cl)cc1)c1cnoc1C1CC1>>O=C(c1ccc(C(F)(F)F)cc1S(=O)c1ccc(Cl)cc1)c1cnoc1C1CC1 -US20120238548A1,1,C[C@@](NC(=O)CBr)(c1cc(Br)ccc1F)C(F)(F)CO>>C[C@]1(c2cc(Br)ccc2F)NC(=O)COCC1(F)F -US20130178407A1,8,OCC(CO)(CO)CO>>O=CC(CO)(CO)CO -US20120004164A1,6,CCOC(=O)c1sc(N2CCN(CC3CCCCO3)C2=O)nc1C>>Cc1nc(N2CCN(CC3CCCCO3)C2=O)sc1C(=O)O -US20090233908A1,6,CCOC(=O)CC1C(NC(=O)OC(C)(C)C)CCCN1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC1CCCN(C(=O)OCc2ccccc2)C1CC(=O)O -US05861421,3,C#CC1(c2ccc(OC)c(OC3CCCC3)c2)CCC(=O)CC1.CC1=NCN(c2ccc(Br)s2)O1>>COc1ccc(C2(C#Cc3ccc(N4CN=C(C)O4)s3)CCC(=O)CC2)cc1OC1CCCC1 -US06653258B1,1,COC(=O)c1ccccc1C(C)Br.Oc1cccc(Cl)c1>>COC(=O)c1ccccc1C(C)Oc1cccc(Cl)c1 -US20130345123A1,2,COc1ccccc1N1CCCC[C@H](NC(=O)[C@H](CC[C@H](Cc2ccccc2)C(=O)O)Cc2ccccc2)C1=O.N#C[C@@H]1CCC[C@@H]2SCC[C@H](N)C(=O)N12>>COc1ccccc1N1CCCC[C@H](NC(=O)[C@H](CC[C@H](Cc2ccccc2)C(=O)N[C@H]2CCS[C@H]3CCC[C@@H](C#N)N3C2=O)Cc2ccccc2)C1=O -US20130216498A1,6,COc1nc(-c2cnc3ccc(F)cn23)nc(N[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1C(F)(F)F>>COc1nc(-c2cnc3ccc(F)cn23)nc(N[C@@H]2CCCNC2)c1C(F)(F)F -US20050032830A1,1,Cc1nc(Cl)c([N+](=O)[O-])c(NCCO)c1C.Oc1ccccc1>>Cc1nc(Oc2ccccc2)c([N+](=O)[O-])c(NCCO)c1C -US20090176774A1,2,COc1cc2nccc(Oc3ccc4cc(N)ccc4c3)c2cc1OC.O=C(O)c1cccnc1F>>COc1cc2nccc(Oc3ccc4cc(NC(=O)c5cccnc5F)ccc4c3)c2cc1OC -US08309581B2,1,N#Cc1ccc(CBr)c(F)c1.Oc1cc(Cl)ccc1-c1nc2ccccc2n1CC1CCCCC1>>N#Cc1ccc(COc2cc(Cl)ccc2-c2nc3ccccc3n2CC2CCCCC2)c(F)c1 -US20110112158A1,1,BrCc1cccc2c(OC(c3ccccc3)(c3ccccc3)c3ccccc3)noc12.Cc1cc(F)c(F)cc1-c1ccc(O)cc1>>Cc1cc(F)c(F)cc1-c1ccc(OCc2cccc3c(OC(c4ccccc4)(c4ccccc4)c4ccccc4)noc23)cc1 -US20130040930A1,6,COc1ccc(CN2C(=O)C(C)N(c3ccc(C(=O)N4CCN(c5ncc(C)cc5C)CC4)cn3)C2=O)cc1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)NC(=O)C4C)nc3)CC2)c(C)c1 -US09079930B2,6,CCOC(=O)c1ccc(-c2cc(-c3cnc(-c4ccccn4)nc3O)on2)cc1>>O=C(O)c1ccc(-c2cc(-c3cnc(-c4ccccn4)nc3O)on2)cc1 -US20100016365A1,2,CCC(=O)Cl.COCC1(Nc2ccccc2)CCN(Cc2ccccc2)CC1>>CCC(=O)N(c1ccccc1)C1(COC)CCN(Cc2ccccc2)CC1 -US20130310384A1,1,CCOc1ccc(S(=O)(=O)N[C@@H](CC)c2ccccc2)cc1.N#Cc1ccc(CBr)cc1>>CCOc1ccc(S(=O)(=O)N(Cc2ccc(C#N)cc2)[C@@H](CC)c2ccccc2)cc1 -US20150239900A1,10,Cc1c(F)cc(Br)cc1[N+](=O)[O-].O=C1CCC(=O)N1Br>>O=[N+]([O-])c1cc(Br)cc(F)c1CBr -US20090099195A1,1,CC(C)N1Cc2c(NCc3cnc4ccccc4c3)nc(Cl)nc2C1=O.C[C@H]1CNCCN1C(=O)OC(C)(C)C>>CC(C)N1Cc2c(NCc3cnc4ccccc4c3)nc(N3CCN(C(=O)OC(C)(C)C)[C@@H](C)C3)nc2C1=O -US05498609,7,COC(=O)COC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)nc2)c2ccc(Cl)cc21>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(OCCO)c3cc(Cl)ccc32)cn1 -US20100105705A1,1,Cc1cn[nH]c1.Cn1cnc2c(Nc3ccc(Cl)cc3)nc(Cl)nc21>>Cc1cnn(-c2nc(Nc3ccc(Cl)cc3)c3ncn(C)c3n2)c1 -US20070037794A1,3,C#CC(C)(C)O.O=[N+]([O-])c1cc(Cl)cnc1Br>>CC(C)(O)C#Cc1ncc(Cl)cc1[N+](=O)[O-] -US20100305093A1,6,COC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1Cl>>CC(C)(C)NS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1 -US08658639B2,2,CC(Cl)OC(=O)Cl.CCC(=O)NCCN1C(=O)C(C)(C)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCNC3)cc21>>CCC(=O)NCCN1C(=O)C(C)(C)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)Cl)C3)cc21 -US20150111870A1,6,CCOC(=O)c1c(OC)nc2ccc(Br)cc2c1Cl>>COc1nc2ccc(Br)cc2c(Cl)c1C(=O)O -US07977372B2,3,Brc1ccc(I)nc1.CN(C)C=O>>O=Cc1ccc(Br)cn1 -US20150111870A1,1,COc1nc2ccc(Br)cc2c(Cl)c1CBr.OC1(C(F)(F)F)CCNCC1>>COc1nc2ccc(Br)cc2c(Cl)c1CN1CCC(O)(C(F)(F)F)CC1 -US09050344B2,6,CN(CCO)c1ccc(-c2ccc(Cl)c3c(NS(C)(=O)=O)nn(C)c23)c([C@H](Cc2cc(F)cc(F)c2)NC(=O)C(F)(F)F)n1>>CN(CCO)c1ccc(-c2ccc(Cl)c3c(NS(C)(=O)=O)nn(C)c23)c([C@@H](N)Cc2cc(F)cc(F)c2)n1 -US05472984,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOCC(O)c1ccc2sccc2c1>>Cc1ccc(S(=O)(=O)OCCOCC(O)c2ccc3sccc3c2)cc1 -US06838463B2,1,C#CCO.Clc1cc(OCc2ccccc2)ncn1>>C#CCOc1cc(OCc2ccccc2)ncn1 -US20140135270A1,1,C=CCBr.COC(=O)[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C>>C=CCO[C@H]1C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1 -US08034812B2,2,Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1.O=C(O)c1ccnc(C(F)(F)F)n1>>O=C(Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1)c1ccnc(C(F)(F)F)n1 -US20150141652A1,1,COC1(OC)CCCNC1.O=CCc1ccccc1>>COC1(OC)CCCN(CCc2ccccc2)C1 -US05889002,1,C[C@H](N)CO.O=S1(=O)N=C(Cl)Nc2cc(Cl)sc21>>C[C@@H](CO)NC1=NS(=O)(=O)c2sc(Cl)cc2N1 -US20110112135A1,1,CCS(=O)(=O)c1cccc(Br)c1.CCc1nc2c(Cl)cccn2c1-c1cccc(O)c1>>CCc1nc2c(Cl)cccn2c1-c1cccc(Oc2cccc(S(=O)(=O)CC)c2)c1 -US08957070B2,2,Cc1ccccc1S(=O)(=O)Cl.Nc1cccc2c3c([nH]c12)C(=O)CCC3>>Cc1ccccc1S(=O)(=O)Nc1cccc2c3c([nH]c12)C(=O)CCC3 -US20090324581A1,6,CCOC(=O)C1CCN(CC(=O)N2CCc3cc(OCc4cc(-c5ccccc5)c(C(F)(F)F)s4)ccc32)CC1>>O=C(O)C1CCN(CC(=O)N2CCc3cc(OCc4cc(-c5ccccc5)c(C(F)(F)F)s4)ccc32)CC1 -US20090258852A1,1,CNCCCN(C)C.COC(=O)c1cc2cc[nH]c(=O)c2c2cc(-c3cccc(C=O)c3)ccc12>>COC(=O)c1cc2cc[nH]c(=O)c2c2cc(-c3cccc(CN(C)CCCN(C)C)c3)ccc12 -US06057311,2,C1CCNC1.Cc1cccc(NC(=O)N2CCC(=O)c3ccccc3N(CC(=O)O)C(=O)C2)c1>>Cc1cccc(NC(=O)N2CCC(=O)c3ccccc3N(CC(=O)N3CCCC3)C(=O)C2)c1 -US20120077781A1,1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.CCOC(=O)CCCCCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(Cl)cc21>>CCOC(=O)CCCCCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(N[C@@H]3CCN(C(=O)OC(C)(C)C)C3)cc21 -US20100249161A1,4,Cc1c(Cl)cc(C(C)(C)C)c(O)c1C=O.NC(=O)c1cc(S(=O)(=O)C(F)(F)F)ccc1N>>Cc1c(Cl)cc(C(C)(C)C)c(O)c1-c1nc2ccc(S(=O)(=O)C(F)(F)F)cc2c(=O)[nH]1 -US05070087,1,CCOC(=O)Cc1ccc(OCCCCl)c(OC)c1.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>CCOC(=O)Cc1ccc(OCCCN2CCC(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(OC)c1 -US20020198388A1,6,O=C(NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC1COC2OCCC12)OCc1ccccc1>>NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12 -US20130137691A1,6,CCOC(=O)c1ccc(C2CCC(CC(=O)OC(C)(C)C)CC2)cc1>>CC(C)(C)OC(=O)CC1CCC(c2ccc(C(=O)O)cc2)CC1 -US20130023541A1,1,CC(C)OC(=O)c1cccnc1N1CC[C@H](NC(=O)OC(C)(C)C)C1.CI>>CC(C)OC(=O)c1cccnc1N1CC[C@H](N(C)C(=O)OC(C)(C)C)C1 -US20140131664A1,7,O=C1c2ccccc2-c2ncccc21>>c1ccc2c(c1)Cc1cccnc1-2 -US04013641,1,BrCc1ccccc1.COC(=O)c1[nH]c2ccccc2c1Oc1ccc(Cl)cc1[N+](=O)[O-]>>COC(=O)c1c(Oc2ccc(Cl)cc2[N+](=O)[O-])c2ccccc2n1Cc1ccccc1 -US04695575,2,CS(=O)(=O)Cl.Cc1ccc(S(=O)(=O)N2CCC(O)CC2)cc1>>Cc1ccc(S(=O)(=O)N2CCC(OS(C)(=O)=O)CC2)cc1 -US05283378,9,Nc1cc(N(C(F)(F)F)C(F)(F)F)ccc1Cl>>Nc1cccc(N(C(F)(F)F)C(F)(F)F)c1 -US07615634B2,1,COc1ccc(F)c(F)c1C(=O)c1cnc(N[C@@H]2CC[C@@H](N)CC2)nc1N.OCCBr>>COc1ccc(F)c(F)c1C(=O)c1cnc(N[C@@H]2CC[C@@H](NCCO)CC2)nc1N -US07388095B2,6,CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1CC(F)(F)F>>CCOC(=O)c1cc2cc(O)ccc2n1CC(F)(F)F -US20070265278A1,6,COc1ccc2[nH]c(-c3ccc(Cl)c(S(=O)(=O)NC4CCCCC4)c3)c(CC(=O)O)c2c1>>O=C(O)Cc1c(-c2ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c2)[nH]c2ccc(O)cc12 -US06143779,3,COc1ccc(C=O)cc1OC.O=C1COc2cc(O)ccc21>>COc1ccc(/C=C2/Oc3cc(O)ccc3C2=O)cc1OC -US06320078B1,2,O=C(NCc1ccc(C(=O)Cl)cc1)OCc1cccnc1.c1c[nH]cn1>>O=C(NCc1ccc(C(=O)n2ccnc2)cc1)OCc1cccnc1 -US20140309227A1,3,NC(=O)c1cc(Br)c2ccccc2n1.OB(O)c1c(Cl)cc(F)cc1Cl>>NC(=O)c1cc(-c2c(Cl)cc(F)cc2Cl)c2ccccc2n1 -US20130005716A1,6,COc1cc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)[C@@H]2SCCN2C(=O)OC(C)(C)C)ccc1OC(F)F>>COc1cc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)[C@H]2NCCS2)ccc1OC(F)F -US20110082173A1,3,CCCCN1CCC(=C(Br)c2ccc(C(=O)N(CC)CC)cc2)CC1.Nc1ccccc1B(O)O>>CCCCN1CCC(=C(c2ccc(C(=O)N(CC)CC)cc2)c2ccccc2N)CC1 -US07635715B2,2,CC(C)(C)OC(=O)CN.CCOC(=O)C1=C(O)c2cccc(Cl)c2C(C)(C)C1=O>>CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2cccc(Cl)c2C(C)(C)C1=O -US07557127B2,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1ccc(NC2CCN(Cc3ccccc3)C2)nc1>>CCOC(=O)/C=C/c1ccc(NC2CCN(Cc3ccccc3)C2)nc1 -US20120172599A1,3,CCCCN(CCCC)c1ccc(C=O)cc1.OCc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCN(CCCC)c1ccc(C=Cc2ccc(CO)cc2)cc1 -US20120142665A1,2,C1CNC1.Cn1ncc(C(=O)O)c1C(=O)Nc1ccn2nc(Br)nc2c1>>Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccn2nc(Br)nc2c1 -US20040019063A1,7,Cc1nc2c([N+](=O)[O-])ccc(C#N)c2o1>>Cc1nc2c(N)ccc(C#N)c2o1 -US20100267712A1,1,CCOC(=O)c1cc(O)ccc1C.CI>>CCOC(=O)c1cc(OC)ccc1C -US20090075989A1,3,N#Cc1ccc(NC(=O)C(=O)c2cccs2)cc1C(F)(F)F.[Mg+]Cc1ccccc1>>N#Cc1ccc(NC(=O)C(O)(Cc2ccccc2)c2cccs2)cc1C(F)(F)F -US06310056B1,9,NC(=O)c1ncn2ccsc12>>N#Cc1ncn2ccsc12 -US20110312953A1,10,COC(=O)c1sc(C)nc1-c1ccccc1Cl.O=C1CCC(=O)N1Br>>COC(=O)c1sc(CBr)nc1-c1ccccc1Cl -US20050137201A1,7,CC(C)(C)OC(=O)NC1CC=C(c2cnc3[nH]ccc3c2)CC1>>CC(C)(C)OC(=O)NC1CCC(c2cnc3[nH]ccc3c2)CC1 -US20070219235A1,4,CCc1cccc(CC)c1N=C=S.Nc1ccc(C(=O)Nc2ccc3cn[nH]c3c2)cc1N>>CCc1cccc(CC)c1Nc1nc2ccc(C(=O)Nc3ccc4cn[nH]c4c3)cc2[nH]1 -US20110092505A1,7,CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(-c3ccnc(NC4CCCCC4)c3)n2)CC1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(-c3ccnc(NC4CCCCC4)c3)n2)CC1 -US07060721B1,6,COC(=O)/C=C/c1c(Cl)nc(C)n1Cc1ccc(-c2ccco2)cc1Cl>>Cc1nc(Cl)c(/C=C/C(=O)O)n1Cc1ccc(-c2ccco2)cc1Cl -US20090281092A1,2,CN1CCN(N)CC1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NN2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US07592477B2,2,CCCCCCCCCCCCNC(=O)c1ccc(CN(CC2CCNCC2)C(=O)C(=O)OCC)cc1.COc1ccc(S(=O)(=O)Cl)cc1>>CCCCCCCCCCCCNC(=O)c1ccc(CN(CC2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)C(=O)C(=O)OCC)cc1 -US07576122B2,2,CC(C)(C)CCN.COc1ccc2oc(C(=O)C(C)(C)C)c(CC(=O)O)c2c1>>COc1ccc2oc(C(=O)C(C)(C)C)c(CC(=O)NCCC(C)(C)C)c2c1 -US07189851B2,2,N[C@@H]1CCc2ccccc21.O=C(O)c1ccc(-c2c(NC(=O)C(F)(F)F)c(Cc3ccc(F)cc3F)nc3c2C(=O)N2CCC[C@@H]32)cc1>>O=C(N[C@@H]1CCc2ccccc21)c1ccc(-c2c(NC(=O)C(F)(F)F)c(Cc3ccc(F)cc3F)nc3c2C(=O)N2CCC[C@@H]32)cc1 -US07544812B2,2,CO.Cc1cc(CCCC2CN(Cc3ccc(C(C)(C)C)cc3)C(=O)N2C)ccc1OC(C)(C)C(=O)O>>COC(=O)C(C)(C)Oc1ccc(CCCC2CN(Cc3ccc(C(C)(C)C)cc3)C(=O)N2C)cc1C -US09139586B2,6,CCN(CC)C(=O)Cn1ccc2c(C(=O)OC)cccc21>>CCN(CC)C(=O)Cn1ccc2c(C(=O)O)cccc21 -US20100130446A1,7,CC(C)(C)OC(=O)n1c(-c2ccc(C=O)cn2)ccc1C(CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1>>CC(C)(C)OC(=O)n1c(-c2ccc(CO)cn2)ccc1C(CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1 -US20150181867A1,6,CCCO[C@H]1CCC[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H](C)[C@@H]1CCC(C)C>>CCCO[C@H]1CCC[C@H]([NH3+])C(=O)O[C@@H](C)[C@@H]1CCC(C)C -US20140200197A1,9,CC(C)(C)OC(=O)N1C[C@@H](CCc2c(F)cncc2NC(=O)[C@@H](N=[N+]=[N-])[C@@H](c2ccc(F)cc2)c2cc(F)cc(F)c2)OC[C@@H]1COC(=O)NCC(F)(F)F>>CC(C)(C)OC(=O)N1C[C@@H](CCc2c(F)cncc2NC(=O)[C@@H](N)[C@@H](c2ccc(F)cc2)c2cc(F)cc(F)c2)OC[C@@H]1COC(=O)NCC(F)(F)F -US20090281097A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(C(=O)N2CCOCC2)C1>>O=C(C1CNCCN1C(=O)OCc1ccccc1)N1CCOCC1 -US20120252808A1,3,CCOC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c2ccccc2n1.CSc1ncc(CBr)cn1>>CCOC(=O)c1cc(Cc2cnc(SC)nc2)c2ccccc2n1 -US20150210722A1,1,CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1.CS(=O)(=O)c1cc(N)cc(OCCN2CCOCC2)c1>>CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OCCN5CCOCC5)cc(S(C)(=O)=O)c4)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1 -US20130197012A1,2,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)ccc3C)cc12.Cc1ccnc(C2(N)CC2)n1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5nccc(C)n5)CC4)ccc3C)cc12 -US20140315801A1,7,CN1CCN(C(=O)c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)CC1>>CN1CCN(C(=O)c2cc3nccc(Oc4ccc(N)cc4F)c3s2)CC1 -US20120270865A2,6,COCCOCc1c(C(Nc2ccc(C(=O)OC)cc2)C2CCCCC2)oc2ccc(F)cc12>>COCCOCc1c(C(Nc2ccc(C(=O)O)cc2)C2CCCCC2)oc2ccc(F)cc12 -US20080312226A1,2,O=C(Cl)c1ccco1.O=C(Nc1noc2ccccc12)N1CCNCC1>>O=C(Nc1noc2ccccc12)N1CCN(C(=O)c2ccco2)CC1 -US20100069629A1,7,COC(=O)CN(C(=O)OC(C)(C)C)c1cc(N2CCc3c(-c4cnc(N(Cc5ccc(OC)cc5)Cc5ccc(OC)cc5)nc4)nc(N4CCOCC4)nc32)ccn1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccnc(N(CCO)C(=O)OC(C)(C)C)c3)cn2)cc1 -US04906287,1,NNc1ccc(Cl)cc1Cl.O=CC(=O)O>>O=CC(O)=NNc1ccc(Cl)cc1Cl -US20110172230A1,6,CC(C)(C)OC(=O)N1CCN(Cc2cccc(OCc3ccccc3)c2)CC1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(O)c2)CC1 -US05180730,1,CCCc1c(CCl)ccc(C(C)=O)c1O.CCOC(=O)CSc1nnc(S)s1>>CCCc1c(CSc2nnc(SCC(=O)OCC)s2)ccc(C(C)=O)c1O -US05770605,2,CC(=O)Cl.Cc1ccc(N)c2c1NCCC2=O>>CC(=O)Nc1ccc(C)c2c1C(=O)CCN2 -US05792780,1,CCOC(=O)CCl.Nc1ccc(OCC(F)(F)C(F)F)cc1>>CCOC(=O)CNc1ccc(OCC(F)(F)C(F)F)cc1 -US20130084346A1,3,COc1ccc(COc2cn(-c3cc(B(O)O)ccn3)ccc2=O)cc1.Ic1ccccc1>>COc1ccc(COc2cn(-c3cc(-c4ccccc4)ccn3)ccc2=O)cc1 -US04395524,2,C=CC(=O)Cl.CCCCCCCCN>>C=CC(=O)NCCCCCCCC -US20030050477A1,7,Cn1nc(-c2cc([N+](=O)[O-])c(Cl)cc2Cl)cc1OC(F)F>>Cn1nc(-c2cc(N)c(Cl)cc2Cl)cc1OC(F)F -US20150210682A1,6,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OC(C)C)cc1CC2CC>>CCC1Cc2cc(OC(C)C)c(OC)cc2-c2cc(=O)c(C(=O)O)cn21 -US08242129B2,1,C1=COCCC1.CC(=O)Nc1ccc(C(=O)/C=C/c2ccc(O)c(C)c2)c(C)c1>>CC(=O)Nc1ccc(C(=O)/C=C/c2ccc(OC3CCCCO3)c(C)c2)c(C)c1 -US05665733,2,CN.COC(=O)CCc1c(-c2ccccc2)n(C)c(=O)c2cc(Cl)ccc12>>CNC(=O)CCc1c(-c2ccccc2)n(C)c(=O)c2cc(Cl)ccc12 -US07772285B2,5,COCCl.Cc1cc(CO)ccc1Br>>COCOCc1ccc(Br)c(C)c1 -US20120004212A1,6,CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(C(=O)NCCNC(=O)NC4CCN(C(=O)OCc5ccccc5)CC4)nc32)[C@H](O)[C@@H]1O>>CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(C(=O)NCCNC(=O)NC4CCNCC4)nc32)[C@H](O)[C@@H]1O -US06043254,7,O=C1NC(=O)C(=Cc2ccc([N+](=O)[O-])cc2)N1>>Nc1ccc(C=C2NC(=O)NC2=O)cc1 -US20100041892A1,2,CCCCCS(N)(=O)=O.COCCOc1ccc(/C=C/C(=O)O)c(OCC2CCCCC2)c1>>CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC)cc1OCC1CCCCC1 -US05330990,7,CON=Cc1ccccc1[N+](=O)[O-]>>CON=Cc1ccccc1N -US05116911,2,C=C(C)C(=O)Cl.OCCCCCCn1c2ccccc2c2ccccc21>>C=C(C)C(=O)OCCCCCCn1c2ccccc2c2ccccc21 -US20090186921A1,2,CC(C)(C)OC(=O)N1CCC(NCCc2ccccc2)CC1.COc1ccc(CC(=O)Cl)cc1>>COc1ccc(CC(=O)N(CCc2ccccc2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20150141409A1,2,O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1.OCCBr>>O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)OCCBr)c1ccc(Cl)cc1 -US20150152047A1,1,CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CBr)c(C(F)(F)F)c1.c1ccc(C(c2ccccc2)N2CC3(CNCCO3)C2)cc1>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CN2CCOC3(C2)CN(C(c2ccccc2)c2ccccc2)C3)c(C(F)(F)F)c1 -US07678787B2,2,CCN.O=C(O)Cc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1>>CCNC(=O)Cc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1 -US04791097,2,CCCCCCCCCCCCCCCCCCCCO.O=C(O)c1ccccc1>>CCCCCCCCCCCCCCCCCCCCOC(=O)c1ccccc1 -US20050054686A1,1,CC(Br)c1ccccc1.Cc1nc(C#Cc2ccnc(Cl)c2)c[nH]1>>Cc1nc(C#Cc2ccnc(Cl)c2)cn1C(C)c1ccccc1 -US20110269734A1,2,Cc1nc(OCCCC2CCN(C(=O)OC(C)(C)C)CC2)ccc1C(=O)O.NC(CO)CO>>Cc1nc(OCCCC2CCN(C(=O)OC(C)(C)C)CC2)ccc1C(=O)NC(CO)CO -US05780474,1,Fc1ccc2c(C3CCNCC3)noc2c1.O=C1NCCN1CCCl>>O=C1NCCN1CCN1CCC(c2noc3cc(F)ccc23)CC1 -US08084448B2,7,O=[N+]([O-])c1cc(F)c(F)cc1OCc1ccccc1>>Nc1cc(F)c(F)cc1OCc1ccccc1 -US20120094999A1,2,C=CC(=O)Cl.CN1CCN(c2ccc(Nc3ncc(Cl)c(Oc4ccc(N)cc4)n3)cc2)CC1>>C=CC(=O)Nc1ccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2Cl)cc1 -US20120039804A1,1,BrCc1ccncc1.O=C(c1ccc2[nH]c3ccccc3c2c1)N1CCCCC1>>O=C(c1ccc2c(c1)c1ccccc1n2Cc1ccncc1)N1CCCCC1 -US04132783,1,COc1ccc(O)cc1.FC(F)(F)c1cccc(Cl)n1>>COc1ccc(Oc2cccc(C(F)(F)F)n2)cc1 -US20110306609A1,2,COCC#Cc1sc(-c2ccccc2)nc1C(=O)O.Nc1ccccc1-c1nc2cc(CN3CCCC3)cnc2s1>>COCC#Cc1sc(-c2ccccc2)nc1C(=O)Nc1ccccc1-c1nc2cc(CN3CCCC3)cnc2s1 -US08952037B2,1,CC(=O)N1CC=C(c2cccnc2F)CC1.O[C@@H]1C[C@H](Nc2nc3ccccc3s2)C1>>CC(=O)N1CC=C(c2cccnc2O[C@@H]2C[C@H](Nc3nc4ccccc4s3)C2)CC1 -US08957070B2,4,CC(=O)CBr.NC(=S)c1cc2cccc(NS(=O)(=O)c3cccs3)c2[nH]1>>Cc1csc(-c2cc3cccc(NS(=O)(=O)c4cccs4)c3[nH]2)n1 -US20100105552A1,7,Cc1cc([N+](=O)[O-])c(C)cc1Oc1ccccc1>>Cc1cc(Oc2ccccc2)c(C)cc1N -US07812040B2,1,CN(C[C@@H]1C[C@H](OS(C)(=O)=O)C1)C(=O)OC(C)(C)C.Oc1cc(Cl)c(CN2CCCC2)cc1Cl>>CN(C[C@@H]1C[C@@H](Oc2cc(Cl)c(CN3CCCC3)cc2Cl)C1)C(=O)OC(C)(C)C -US20100168418A1,7,Cc1cc(=O)n(CC2OCCO2)c2cc(C3C=CCCC3)ccc12>>Cc1cc(=O)n(CC2OCCO2)c2cc(C3CCCCC3)ccc12 -US05852011,1,CCNCCO.O=[N+]([O-])c1ccc(F)cc1>>CCN(CCO)c1ccc([N+](=O)[O-])cc1 -US20060128790A1,8,CCOC(=O)C1(CO)CCC1>>CCOC(=O)C1(C=O)CCC1 -US20120065195A1,3,C#CC1CC1.CN1C(=O)C2(CCCc3cnc(Cl)cc32)N=C1N>>CN1C(=O)C2(CCCc3cnc(C#CC4CC4)cc32)N=C1N -US20120316366A1,3,CCOP(=O)(CC=C(C)CCC=C(C)C)OCC.COC(OC)C(C)C=O>>COC(OC)C(C)C=CC=C(C)CCC=C(C)C -US20150152118A1,1,CC1(C)CNCCN1Cc1ccccc1.Fc1ccc(Br)cc1>>CC1(C)CN(c2ccc(F)cc2)CCN1Cc1ccccc1 -US20050043344A1,1,C[O-].Fc1cc(F)cc(Br)c1>>COc1cc(F)cc(Br)c1 -US20130230542A1,1,CNCc1ccccc1.Oc1ccc(OCCBr)cc1>>CN(CCOc1ccc(O)cc1)Cc1ccccc1 -US06407094B1,3,C#Cc1ccccc1.Cc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1I>>Cc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C#Cc1ccccc1 -US20140315902A1,1,COc1cc(OC)c(F)c(N2Cc3cnc(Cl)cc3C3(CC3)C2=O)c1F.NCCN1CCOCC1>>COc1cc(OC)c(F)c(N2Cc3cnc(NCCN4CCOCC4)cc3C3(CC3)C2=O)c1F -US20150051395A1,6,CCNC(=O)c1ccc(S(=O)(=O)Nc2cc(F)c(C(=O)OCc3ccccc3)c(F)c2)cn1>>CCNC(=O)c1ccc(S(=O)(=O)Nc2cc(F)c(C(=O)O)c(F)c2)cn1 -US20080176862A1,3,CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2ccc(F)c(Br)c2)N=C1N.OB(O)C1=CCCCC1>>CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2ccc(F)c(C3=CCCCC3)c2)N=C1N -US20140066455A1,2,CCOC(=O)c1ccc(N2CCCN(C(C)C)CC2)s1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3ccc(N4CCCN(C(C)C)CC4)s3)[nH]n2)cc(OC)c1 -US05486525,7,O=C(O)CCc1ccc(CNc2ccncc2[N+](=O)[O-])o1>>Nc1cnccc1NCc1ccc(CCC(=O)O)o1 -US04871756,6,CCCc1c(OCC2(Sc3ccc(C(=O)CCC(=O)OC)cc3)CCCCC2O)ccc(C(C)=O)c1O>>CCCc1c(OCC2(Sc3ccc(C(=O)CCC(=O)O)cc3)CCCCC2O)ccc(C(C)=O)c1O -US20080280892A1,7,CCCCOC(=O)CCc1cc(=O)[nH]n(Cc2ccc(OC)cc2)c1=O>>COc1ccc(Cn2[nH]c(=O)cc(CCCO)c2=O)cc1 -US20120208827A1,6,COC(=O)c1ccc2nc(-c3ccc(-c4ccc(F)cc4)cc3)n(C[C@@H]3CCN(C(=O)C4CC4)C3)c2c1>>O=C(O)c1ccc2nc(-c3ccc(-c4ccc(F)cc4)cc3)n(C[C@@H]3CCN(C(=O)C4CC4)C3)c2c1 -US07087626B2,1,CC(C)(C)OC(=O)N1CCC(Br)CC1.Oc1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)ccnc2c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(-c4c(-c5ccccn5)nn5c4CCC5)ccnc3c2)CC1 -US07501424B2,6,CCOC(=O)c1ccc(Nc2nccc(-c3cnccn3)n2)cc1>>O=C(O)c1ccc(Nc2nccc(-c3cnccn3)n2)cc1 -US20070167433A1,1,COCCCN1CCOc2ccc(C(O[C@H]3CNC[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]3c3ccc(CCl)cc3)S(=O)(=O)c3ccc(C)cc3)cc21.COCCCO>>COCCCOCc1ccc([C@H]2[C@H](O[Si](C(C)C)(C(C)C)C(C)C)CNC[C@@H]2OC(c2ccc3c(c2)N(CCCOC)CCO3)S(=O)(=O)c2ccc(C)cc2)cc1 -US08293757B2,3,CC1(C)OB(c2ccc(OC(F)F)cc2)OC1(C)C.O=C(O)C(CO)c1ccc(Nc2ncc(Br)cn2)cc1>>O=C(O)C(CO)c1ccc(Nc2ncc(-c3ccc(OC(F)F)cc3)cn2)cc1 -US07989461B2,1,CNc1cc(-c2cccnc2F)ncn1.Cc1nc2cc(Nc3nccc4c(N)c(C)ccc34)ccc2s1>>CNc1cc(-c2cccnc2Nc2c(C)ccc3c(Nc4ccc5sc(C)nc5c4)nccc23)ncn1 -US20060148858A1,7,CCOc1nn(Cc2ccccc2)cc1CCCC=O>>CCOc1nn(Cc2ccccc2)cc1CCCCO -US20120309789A1,7,Cc1cc(NC2CCN([C@@H]3CC[C@@H](OC(C)C)CC3)CC2)c([N+](=O)[O-])cc1F>>Cc1cc(NC2CCN([C@@H]3CC[C@@H](OC(C)C)CC3)CC2)c(N)cc1F -US20100130476A1,1,CC(O)c1ccc(F)cc1.Clc1nc(Cl)c2nc[nH]c2n1>>CC(c1ccc(F)cc1)n1cnc2c(Cl)nc(Cl)nc21 -US20120258982A1,7,COC(=O)c1ccc(/C=C/C(=O)c2cccnc2Nc2ccccc2)c(OC)c1>>COC(=O)c1ccc(CCC(=O)c2cccnc2Nc2ccccc2)c(OC)c1 -US20040167158A1,1,CCN(CC)CCc1ccc2cc[nH]c2c1.Fc1ccc(I)cc1>>CCN(CC)CCc1ccc2ccn(-c3ccc(F)cc3)c2c1 -US20040002524A1,6,CC(C)n1cccc1-c1nc2ccccc2n1-c1ccc(OCc2ccccc2)cc1>>CC(C)n1cccc1-c1nc2ccccc2n1-c1ccc(O)cc1 -US20150238492A1,3,Cc1nn(-c2ccnc3[nH]ccc23)cc1Br.N#Cc1cccc(B(O)O)c1>>Cc1nn(-c2ccnc3[nH]ccc23)cc1-c1cccc(C#N)c1 -US20090181965A1,4,COc1cc(NC(N)=S)ccc1-n1cnc(C)c1.O=C1C(Br)CCCC1c1ccc(Cl)cc1Cl>>COc1cc(Nc2nc3c(s2)CCCC3c2ccc(Cl)cc2Cl)ccc1-n1cnc(C)c1 -US05496927,2,C[C@H](NC(=O)OC(C)(C)C)C(=O)O.O=C(OCc1ccccc1)[C@@H]1CCCN1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1 -US20090069336A1,2,CCCN.Cc1ccc(-c2nc(N)nc3sc(C(=O)O)cc23)c(C)c1>>CCCNC(=O)c1cc2c(-c3ccc(C)cc3C)nc(N)nc2s1 -US08609669B2,2,CC(C)(C)c1c(N)nn2cccnc12.O=C(Cl)Cc1ccc(F)cc1>>CC(C)(C)c1c(NC(=O)Cc2ccc(F)cc2)nn2cccnc12 -US20070249670A1,7,COC(=O)[C@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1[N+](=O)[O-])[C@H](C)OC(C)(C)C>>COC(=O)[C@H](NC(=O)c1ccc(-c2ccc(F)c(F)c2)cc1N)[C@H](C)OC(C)(C)C -US20110275797A1,6,COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(C2CCN(CCO)CC2)ccc1O>>O=C(Nc1cc(-c2ccccc2)ccc1C(=O)O)c1cc(C2CCN(CCO)CC2)ccc1O -US20080036373A1,1,CC(C)(C)c1ccc(Br)cc1.Nc1ccn(-c2ccccc2)n1>>CC(C)(C)c1ccc(Nc2ccn(-c3ccccc3)n2)cc1 -US07179823B1,1,CCOC(=O)CCc1c[nH]nc1OCC.ClCc1ccc(OCc2ccccc2)cc1>>CCOC(=O)CCc1cn(Cc2ccc(OCc3ccccc3)cc2)nc1OCC -US20120289500A1,2,Nn1nc(N2CCOCC2)c2ccccc2c1=O.O=C(O)Cc1ccc(C(F)(F)F)cc1>>O=C(Cc1ccc(C(F)(F)F)cc1)Nn1nc(N2CCOCC2)c2ccccc2c1=O -US20110166146A1,1,CNCCO.Clc1ccc(-c2nc3ccccn3c2Cc2cncc(Cl)n2)cc1>>CN(CCO)c1cncc(Cc2c(-c3ccc(Cl)cc3)nc3ccccn23)n1 -US20060084640A1,1,C[Si](C)(C)CCOCn1c(Br)nc(Cl)c1Cl.FC(F)(F)c1cccnc1N1CCNCC1>>C[Si](C)(C)CCOCn1c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc(Cl)c1Cl -US20070155805A1,1,CCCCC(CCBr)c1sc2cc(C(F)(F)F)ccc2c1C.CCOC(=O)COc1ccc(O)cc1C>>CCCCC(CCOc1ccc(OCC(=O)OCC)c(C)c1)c1sc2cc(C(F)(F)F)ccc2c1C -US05489602,3,Cc1oc(-c2ccccc2)nc1CCOc1ccc(C=O)cn1.O=C1CSC(=O)N1>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(C=C2SC(=O)NC2=O)cn1 -US04645527,2,NC1CCCC1.O=C=NS(=O)(=O)c1cccc(Cl)c1Cl>>O=C(NC1CCCC1)NS(=O)(=O)c1cccc(Cl)c1Cl -US06790860B2,6,COc1ccc(CS[C@@H]2C[C@@H](CCC(=O)c3ccc(F)cc3)N(C(=O)OC(C)(C)C)C2)cc1>>COc1ccc(CS[C@H]2CN[C@H](CCC(=O)c3ccc(F)cc3)C2)cc1 -US20050130941A1,2,CC(C)(C)OC(=O)NN(Cc1ccccc1)C[C@H](O)[C@@H](N)Cc1ccccc1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)NN(Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 -US07064123B1,2,CCC(N)C(O)c1nnc(-c2ccccc2)o1.O=C(O)C(CC(=O)N1CCOCC1)CS(=O)(=O)Cc1ccccc1>>CCC(NC(=O)C(CC(=O)N1CCOCC1)CS(=O)(=O)Cc1ccccc1)C(O)c1nnc(-c2ccccc2)o1 -US05242936,7,CCCCOC(=O)CCOc1ccc(C(C)(C)C)cc1>>CC(C)(C)c1ccc(OCCCO)cc1 -US20060287291A1,2,COc1ccc(C)cc1S(=O)(=O)Cl.C[Si](C)(C)c1cc2cc(N)cc(Br)c2o1>>COc1ccc(C)cc1S(=O)(=O)Nc1cc(Br)c2oc([Si](C)(C)C)cc2c1 -US20120270875A1,3,CCOC(=O)c1c(C)nc(NC/C=C/B2OC(C)(C)C(C)(C)O2)nc1C.Oc1cccc(Br)c1>>CCOC(=O)c1c(C)nc(NC/C=C/c2cccc(O)c2)nc1C -US07645751B2,1,Fc1cc(Br)cc(Br)c1.OCc1ccccc1>>Brc1cc(Br)cc(OCc2ccccc2)c1 -US07276516B2,6,COC(=O)c1ccc(S(=O)(=O)n2cc(C3CC3)c3ccccc32)cc1>>O=C(O)c1ccc(S(=O)(=O)n2cc(C3CC3)c3ccccc32)cc1 -US20070117800A1,1,CCOC(=O)c1ccc(-c2ccnc(Cl)n2)s1.Nc1cccnc1>>CCOC(=O)c1ccc(-c2ccnc(Nc3cccnc3)n2)s1 -US09090599B2,2,COCCOc1ncc(C(=O)O)cc1-c1ccc(F)c(F)c1.NCc1nc(C(F)(F)F)no1>>COCCOc1ncc(C(=O)NCc2nc(C(F)(F)F)no2)cc1-c1ccc(F)c(F)c1 -US20030134891A1,7,O=C1OCCC=CCCOC(=O)[C@H]2CCCN2C(=O)CCCCC(=O)N2CCC[C@H]12>>O=C1OCCCCCCOC(=O)[C@H]2CCCN2C(=O)CCCCC(=O)N2CCC[C@H]12 -US04402972,6,COC(=O)/C=C\[C@H]1[C@@H](C(=O)OC(C)(C)C)C1(C)C>>COC(=O)/C=C\C1C(C(=O)O)C1(C)C -US08846661B2,3,Brc1cnc(N2CC3CC4CC2CN(C4)C3)s1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cnc(N3CC4CC5CC3CN(C5)C4)s2)cc1 -US08557741B2,6,CCN(CC)C(=O)COCc1ccccc1>>CCN(CC)C(=O)CO -US04845118,2,CCOC(=O)Cl.COc1ccnc(CSc2nc3cscc3[nH]2)c1>>CCOC(=O)n1c(SCc2cc(OC)ccn2)nc2cscc21 -US20030191133A1,1,O=C1NCCc2ccccc21.OCCCBr>>O=C1c2ccccc2CCN1CCCO -US04888138,1,CCCCCCCCCCOCC(O)CCl>>CCCCCCCCCCOCC1CO1 -US08222245B2,6,CCOC(=O)CN1CCc2ccc(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cc2CC1>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CC(=O)O)CC4)no2)cc1C#N -US20150023913A1,6,CCOC(=O)C1C2CCOC21>>O=C(O)C1C2CCOC21 -US06127341,6,CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCC(Cl)(Cl)Cl)C(N)=O>>NC(=O)[C@@H](N)CCCCNC(=O)OCC(Cl)(Cl)Cl -US20100093812A1,6,CCOC(=O)[C@@]1(C)CSC(c2cccc(OCCOCCOCCOC)c2O)=N1>>COCCOCCOCCOc1cccc(C2=N[C@@](C)(C(=O)O)CS2)c1O -US20050203151A1,6,CCOC(=O)C(C)(C)Oc1ccc2c(ccn2Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)c1>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1Cn1ccc2cc(OC(C)(C)C(=O)O)ccc21 -US08232312B2,2,CC(C)(C)OC(=O)CN(c1ccc2c(c1)CCN2)S(=O)(=O)c1cc(Cl)cc(Cl)c1.O=C=Nc1ccccc1>>CC(C)(C)OC(=O)CN(c1ccc2c(c1)CCN2C(=O)Nc1ccccc1)S(=O)(=O)c1cc(Cl)cc(Cl)c1 -US20140135320A1,9,CC(C)(C)c1cc(C=O)c(O)c(-c2ccc(C(F)(F)F)nc2)c1.NO>>CC(C)(C)c1cc(C=NO)c(O)c(-c2ccc(C(F)(F)F)nc2)c1 -US07727997B2,6,CCCN(CCC)C(=O)c1cc(C(=O)OC)cc(-c2ncco2)c1>>CCCN(CCC)C(=O)c1cc(C(=O)O)cc(-c2ncco2)c1 -US20130281428A1,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CS(=O)(=O)OC[C@H]1COCCO1>>CC1(C)OB(c2cnn(C[C@H]3COCCO3)c2)OC1(C)C -US05036075,1,Fc1ccc2[nH]cc(C3=CCNCC3)c2c1.O=S1(=O)c2cccc3cccc(c23)N1CCCCl>>O=S1(=O)c2cccc3cccc(c23)N1CCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 -US04655816,1,C=CCBr.CCOC(=O)c1c(C(F)(F)F)nc(C(F)(F)F)c(C)c1O>>C=CCOc1c(C)c(C(F)(F)F)nc(C(F)(F)F)c1C(=O)OCC -US09150508B2,2,COC(=O)CCc1ccc(S(=O)(=O)Cl)cc1.Cc1ccc(C(F)(F)F)cc1NCC(C)C>>COC(=O)CCc1ccc(S(=O)(=O)N(CC(C)C)c2cc(C(F)(F)F)ccc2C)cc1 -US20040186060A1,2,COC(=O)NC(CCS(C)(=O)=O)(Cc1cccc(C#N)c1)C(=O)O.N#Cc1ccc(CNC(=O)CN)s1>>COC(=O)NC(CCS(C)(=O)=O)(Cc1cccc(C#N)c1)C(=O)NCC(=O)NCc1ccc(C#N)s1 -US20040002524A1,1,BrCc1ccccc1.COC(=O)c1ccc(-c2nc3ccccc3n2-c2ccc(O)cc2)cc1>>COC(=O)c1ccc(-c2nc3ccccc3n2-c2ccc(OCc3ccccc3)cc2)cc1 -US20120157487A1,2,CSc1ccc(Cl)cc1N.O=S(=O)(Cl)c1ccc(Cl)c(C(F)(F)F)c1>>CSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20040034041A1,1,N#CCCCBr.O=c1[nH]c2ccccc2c(=O)o1>>N#CCCCn1c(=O)oc(=O)c2ccccc21 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)cn3)c(F)c2)OC1(C)C.O=S(=O)(c1ccccc1)c1ccccc1Br>>Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)c3ccccc3)cc2F)cn1 -US20120258977A1,6,CO[C@@H]1Cc2ccccc2[C@H]1N1C(=O)c2ccccc2C1=O>>CO[C@@H]1Cc2ccccc2[C@H]1N -US20070244131A1,6,CCOC(=O)C1(c2cccc(Br)c2)CCCC1>>O=C(O)C1(c2cccc(Br)c2)CCCC1 -US04115416,6,COc1ccc(C2=CCCCCCC2)cc1>>Oc1ccc(C2=CCCCCCC2)cc1 -US08178541B2,1,CC(C)=CCn1c(Cl)nc2c1c(=O)[nH]c(=O)n2C.COc1ccccc1C(=O)CBr>>COc1ccccc1C(=O)Cn1c(=O)c2c(nc(Cl)n2CC=C(C)C)n(C)c1=O -US20140094474A1,6,CCOC(=O)c1cn2c(n1)NC(=O)CC2>>O=C1CCn2cc(C(=O)O)nc2N1 -US20140080798A1,1,CC(C)(C)S(=O)NC1(c2ccc(N)cc2)COC1.Cc1cnc(Cl)nc1CCc1ccccc1CC(N)=O>>Cc1cnc(Nc2ccc(C3(NS(=O)C(C)(C)C)COC3)cc2)nc1CCc1ccccc1CC(N)=O -US08258151B2,1,NC(=O)CI.O=Cc1c(O)cccc1Cl>>NC(=O)COc1cccc(Cl)c1C=O -US07642264B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(Cl)c2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3ccc(N)nc3)c2)n1 -US07985861B2,2,CC(=O)Oc1cccc(C(=O)O)c1.CC(C)[C@@H](N)C(=O)N1CCC(c2ccc(Cl)cc2)CC1>>CC(=O)Oc1cccc(C(=O)N[C@@H](C(=O)N2CCC(c3ccc(Cl)cc3)CC2)C(C)C)c1 -US20080108595A1,6,CC(=O)N1CC(C)(C)c2cc(F)ccc21>>CC1(C)CNc2ccc(F)cc21 -US20040058965A1,1,CCOC(=O)CCc1ccc(O)cc1OCC.Cc1oc(-c2ccccc2)nc1COc1ccccc1CCl>>CCOC(=O)CCc1ccc(OCc2ccccc2OCc2nc(-c3ccccc3)oc2C)cc1OCC -US06673788B2,8,O=C(CCc1ccccc1)Nc1cc(F)ccc1C(O)C(F)(F)F>>O=C(CCc1ccccc1)Nc1cc(F)ccc1C(=O)C(F)(F)F -US20050143422A1,6,Cc1c(C(=O)OC(C)(C)C)oc2cccc(OC(C)C)c12>>Cc1c(C(=O)O)oc2cccc(OC(C)C)c12 -US04863904,6,CCOC(=O)C(C#N)Cc1ccccc1>>N#CC(Cc1ccccc1)C(=O)O -US06613942B1,1,BrCC1CCCCO1.O=Cc1ccc(O)c2ccccc12>>O=Cc1ccc(OCC2CCCCO2)c2ccccc12 -US20150246902A1,3,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4nnc(Br)n4c3)cc12.OB(O)c1ccc(F)cc1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4nnc(-c5ccc(F)cc5)n4c3)cc12 -US20140135360A1,3,O=Cc1cc(Br)cc(-c2ccc(Cl)c(Cl)c2)c1O.OB(O)c1ccc(Cl)cc1>>O=Cc1cc(-c2ccc(Cl)cc2)cc(-c2ccc(Cl)c(Cl)c2)c1O -US20140038910A1,6,CCOC(=O)C[C@H](NC(=O)CNC(=O)c1cc(O)cc(NC2=NCC(O)CN2)c1)c1cc(Cl)cc(C2(CF)CCOCC2)c1>>O=C(O)C[C@H](NC(=O)CNC(=O)c1cc(O)cc(NC2=NCC(O)CN2)c1)c1cc(Cl)cc(C2(CF)CCOCC2)c1 -US20060180050A1,1,CC=O.Nc1cccc2ncccc12>>CCNc1cccc2ncccc12 -US06329372B1,2,CC(=O)c1c(C(=O)O)c(C)n(C)c1C.COC(=O)[C@@H](N)Cc1ccc(OCc2c(Cl)cccc2Cl)cc1>>COC(=O)[C@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)c1c(C(C)=O)c(C)n(C)c1C -US07229987B2,6,COC(=O)c1ccc(-c2nnc(CN3C(=O)c4ccccc4C3=O)o2)cc1>>O=C(O)c1ccc(-c2nnc(CN3C(=O)c4ccccc4C3=O)o2)cc1 -US07495104B2,1,COc1cc2c(Oc3ccc(Nc4ccc(C(C)(C)C)cc4)cc3)ccnc2cc1O.ClCCN1CCOCC1>>COc1cc2c(Oc3ccc(Nc4ccc(C(C)(C)C)cc4)cc3)ccnc2cc1OCCN1CCOCC1 -US07582761B2,1,C[C@@H]1CNCCN1.Clc1cnc(Cl)c(Cl)c1>>C[C@@H]1CN(c2ncc(Cl)cc2Cl)CCN1 -US20080233127A1,1,O=Cc1ccc(Cl)cc1.Oc1cncc(-c2nc(N3CCOCC3)c3ncn(C4CCNCC4)c3n2)c1>>Oc1cncc(-c2nc(N3CCOCC3)c3ncn(C4CCN(Cc5ccc(Cl)cc5)CC4)c3n2)c1 -US08088760B2,9,COC(=O)c1cccc2nc(C3CCCN(C(=O)OCc4ccccc4)C3)oc12.N>>NC(=O)c1cccc2nc(C3CCCN(C(=O)OCc4ccccc4)C3)oc12 -US20140018380A1,6,CC(C)(C)OC(=O)N1CCc2cc(B3OC(C)(C)C(C)(C)O3)ccc21>>CC1(C)OB(c2ccc3c(c2)CCN3)OC1(C)C -US09102623B2,2,C=CCN.COC(=O)c1cc(Br)c(C(F)(F)F)[nH]c1=O>>C=CCNC(=O)c1cc(Br)c(C(F)(F)F)[nH]c1=O -US20100009959A1,3,C=Cc1ccccc1B(O)O.COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1>>C=Cc1ccccc1-c1[nH]c2cc(C(=O)OC)ccc2c1C1CCCCC1 -US20110152316A1,1,NC1CC1.O=Cc1cc(Br)cc(Br)c1>>Brc1cc(Br)cc(CNC2CC2)c1 -US20080139558A1,1,Cc1cccc2[nH]c(C(C)C)nc12.O=c1cc(CBr)c2ccc(F)c(F)c2[nH]1>>Cc1cccc2c1nc(C(C)C)n2Cc1cc(=O)[nH]c2c(F)c(F)ccc12 -US07226925B2,1,CN(C)CCCc1ncccc1OCCO.C[C@@H]1CNCCN1c1nccnc1Cl>>C[C@@H]1CNCCN1c1nccnc1OCCOc1cccnc1CCCN(C)C -US20130156756A1,2,Cc1cc(C(=O)O)ccc1Br.NCCF>>Cc1cc(C(=O)NCCF)ccc1Br -US20110136800A1,2,Nc1ccc(C(=O)O)cc1.c1ccc2c(c1)C[C@@H]1NCCC[C@H]21>>Nc1ccc(C(=O)N2CCC[C@@H]3c4ccccc4C[C@@H]32)cc1 -US07625934B2,3,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.OB(O)c1ccc(OC(F)(F)F)cc1>>CC(C)(C)OC(=O)N1CC=C(c2ccc(OC(F)(F)F)cc2)CC1 -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)N(C)[C@H](C)c1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC(=O)N(C)[C@H](C)c4ccccc4)cc3)cc2)CC1 -US20020165234A1,6,O=C1CN(C(=O)c2ccccc2)Cc2[nH]c3ccccc3c21>>O=C1CNCc2[nH]c3ccccc3c21 -US07514452B2,6,COC(=O)c1occ(-c2ccccc2)c1-c1ccccc1>>O=C(O)c1occ(-c2ccccc2)c1-c1ccccc1 -US20110082133A1,1,C=C(C)CBr.CC(C)(C)OC(=O)N1CCC[C@@H]1CO>>C=C(C)COC[C@H]1CCCN1C(=O)OC(C)(C)C -US04199596,10,Cc1cc(Oc2cccc(F)c2)ccc1F.O=C1CCC(=O)N1Br>>Fc1cccc(Oc2ccc(F)c(CBr)c2)c1 -US20070093515A1,1,CI.COc1cc2ncnc(N3CCc4[nH]nc(CO)c4C3)c2cc1OC>>COc1cc2ncnc(N3CCc4c(c(CO)nn4C)C3)c2cc1OC -US20090149456A1,2,CN(C)C1Cc2ccc(Nc3nccc(-c4c(-c5ccc(F)c(N)c5)nn5ccccc45)n3)cc2C1.O=C(Cl)Cc1cccs1>>CN(C)C1Cc2ccc(Nc3nccc(-c4c(-c5ccc(F)c(NC(=O)Cc6cccs6)c5)nn5ccccc45)n3)cc2C1 -US20070270395A1,1,C1CNCCN1.N#Cc1c(Cl)c2cc(Cl)ccc2n(Cc2ccccc2)c1=O>>N#Cc1c(N2CCNCC2)c2cc(Cl)ccc2n(Cc2ccccc2)c1=O -US20100256134A1,2,Cc1ccccc1Nc1c(C(=O)N2CCC(c3ccccc3)CC2)cnc2c(C(=O)O)cnn12.Cc1nn(C)c(Cl)c1S(N)(=O)=O>>Cc1ccccc1Nc1c(C(=O)N2CCC(c3ccccc3)CC2)cnc2c(C(=O)NS(=O)(=O)c3c(C)nn(C)c3Cl)cnn12 -US06605620B1,1,COc1cc(-c2cc(CN3CCC(=O)CC3)ccn2)cc(OC)c1Cl.Nc1ccccc1>>COc1cc(-c2cc(CN3CCC(Nc4ccccc4)CC3)ccn2)cc(OC)c1Cl -US09090599B2,1,BrCC1CC1.OCc1cc(I)c(O)c(Cl)n1>>OCc1cc(I)c(OCC2CC2)c(Cl)n1 -US06569856B2,2,CN(C)S(=O)(=O)Cl.NCC1CCC(CN)CC1>>CN(C)S(=O)(=O)NCC1CCC(CN)CC1 -US04367232,2,CNC1CCN(Cc2ccccc2)CC1.COc1ccc(Cl)cc1C(=O)O>>COc1ccc(Cl)cc1C(=O)N(C)C1CCN(Cc2ccccc2)CC1 -US20130172384A1,3,COc1ccc(B(O)O)c(F)c1.O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3F)n[nH]c2=O)C1>>COc1ccc(-c2ccc(-c3n[nH]c(=O)n3C[C@@H]3CCN(C(=O)C4CC4)C3)c(F)c2)c(F)c1 -US04395410,1,C=O.CCCCCCC(C)NCCCCc1ccccc1>>CCCCCCC(C)N(C)CCCCc1ccccc1 -US05807885,1,Cc1ccccc1CBr.O=C(NCCc1ccc([N+](=O)[O-])cc1)C(F)(F)F>>Cc1ccccc1CN(CCc1ccc([N+](=O)[O-])cc1)C(=O)C(F)(F)F -US20140275245A1,2,CC(=O)Cl.CC(=O)OC12CC(N)(C1)C2>>CC(=O)NC12CC(OC(C)=O)(C1)C2 -US20130029953A1,7,C=CC(F)(F)[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(C(C)=O)cc3)C[C@@]21C>>CCC(F)(F)[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(C(C)=O)cc3)C[C@@]21C -US20120035370A1,1,CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(Br)c1.CN1CCNCC1>>CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(N2CCN(C)CC2)c1 -US05783522,1,COc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1Cl.C[O-]>>COc1cc(-c2ncc(C(F)(F)F)cc2OC)ccc1Cl -US05972951,2,CC(=O)OC(C)=O.Cc1cc(C(=O)NN)ccc1Br>>CC(=O)NNC(=O)c1ccc(Br)c(C)c1 -US20070232627A1,2,COc1ccc(Sc2ccc(C(=O)Cl)cc2Nc2ncnc3ncccc23)cc1.Nc1cccc(C(F)(F)F)c1>>COc1ccc(Sc2ccc(C(=O)Nc3cccc(C(F)(F)F)c3)cc2Nc2ncnc3ncccc23)cc1 -US06878706B1,2,CC(C)(C)CNCC(=O)N1CCOCC1.O=C(Br)CBr>>CC(C)(C)CN(CC(=O)N1CCOCC1)C(=O)CBr -US20070155805A1,2,CNOC.O=C(O)c1cc2ccc(C(F)(F)F)cc2s1>>CON(C)C(=O)c1cc2ccc(C(F)(F)F)cc2s1 -US07807674B2,2,CCOC(=O)NC(=O)C(C#N)=NNc1cc(Cl)c(Cc2cc(C(C)C)c(=O)[nH]n2)c(Cl)c1>>CC(C)c1cc(Cc2c(Cl)cc(-n3nc(C#N)c(=O)[nH]c3=O)cc2Cl)n[nH]c1=O -US20120245161A1,6,COCCn1cc(C(=O)N2CCC(c3cc(CN)ccc3OCC(=O)OC)CC2)c2cccc(C)c21>>COCCn1cc(C(=O)N2CCC(c3cc(CN)ccc3OCC(=O)O)CC2)c2cccc(C)c21 -US08008298B2,1,CCOC(=O)c1c(C)[nH]c2ncc(-c3cc(OC)c(OC)c(OC)c3)nc12.C[Si](C)(C)CCOCCl>>CCOC(=O)c1c(C)n(COCC[Si](C)(C)C)c2ncc(-c3cc(OC)c(OC)c(OC)c3)nc12 -US20090118257A1,2,Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2.NCCOCCO>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCOCCO)O2 -US09120824B2,6,COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3C(=O)OC(C)(C)C)CC2)cc1>>COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3)CC2)cc1 -US08618286B2,6,CC(C)(C)OC(=O)N1CCC(N2CCSc3cc(NC(=N)c4cccs4)ccc32)C1>>N=C(Nc1ccc2c(c1)SCCN2C1CCNC1)c1cccs1 -US08247595B2,2,C#CCC(C)CCO.CS(=O)(=O)Cl>>C#CCC(C)CCOS(C)(=O)=O -US05523302,1,COC(=O)CBr.COc1cc(C=O)ccc1O>>COC(=O)COc1ccc(C=O)cc1OC -US05428038,1,COc1cc2oc(=O)c(C)c(C)c2cc1O.ClCCCN1CCN(Cc2ccc(Cl)cc2)CC1>>COc1cc2oc(=O)c(C)c(C)c2cc1OCCCN1CCN(Cc2ccc(Cl)cc2)CC1 -US09156827B2,3,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1.COc1ccc2[nH]nc(C=O)c2c1>>COc1ccc2[nH]nc(/C=C3\Oc4c(ccc(O)c4CN4CCN(C(=O)OC(C)(C)C)CC4)C3=O)c2c1 -US20140105921A1,2,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)[C@](C)(O)CO.Cc1cc(OCC(=O)OCc2ccccc2)cc(C)c1S(=O)(=O)Cl>>Cc1cc(OCC(=O)OCc2ccccc2)cc(C)c1S(=O)(=O)OC[C@@](C)(O)C(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C -US07544812B2,1,CCOC(=O)C(C)(Cc1ccc(OCCC2CNC(=O)N2C)cc1)Oc1ccccc1.COc1cccc(CBr)c1>>CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3cccc(OC)c3)C(=O)N2C)cc1)Oc1ccccc1 -US20120022058A1,3,CC1(C)OB(c2ccc3c(c2)NC(=O)CO3)OC1(C)C.Cc1nc(N2N=C(Cl)C[C@@H]2C2CCCC2)ccc1C#N>>Cc1nc(N2N=C(c3ccc4c(c3)NC(=O)CO4)C[C@@H]2C2CCCC2)ccc1C#N -US20080318963A1,2,CCOC(=O)Nc1nc2ccc(Cl)cc2nc1OC.Cc1cc(C)cc(N2CCNCC2)c1>>COc1nc2cc(Cl)ccc2nc1NC(=O)N1CCN(c2cc(C)cc(C)c2)CC1 -US20120225868A1,2,CO[C@@H](C)C(=O)O.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1>>CO[C@@H](C)C(=O)N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1 -US06656469B1,7,COC(=O)c1ccc(C#Cc2cncc(C3CCCN3C)c2)cc1>>COC(=O)c1ccc(CCc2cncc(C3CCCN3C)c2)cc1 -US20150197530A1,6,CCOC(=O)Cc1cc(S(=O)(=O)c2ccc(OC)cc2)sc1-c1ccc(Cl)c(Cl)c1>>COc1ccc(S(=O)(=O)c2cc(CC(=O)O)c(-c3ccc(Cl)c(Cl)c3)s2)cc1 -US20150152108A1,2,Cn1cc(N)cn1.O=C(Cl)Oc1ccccc1>>Cn1cc(NC(=O)Oc2ccccc2)cn1 -US07132457B2,1,CC(C)(C)OC(=O)NC1(C=O)CC1.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(CNCCO)ccc1Cl>>CC(C)(C)OC(=O)NC1(CN(CCO)Cc2ccc(Cl)c(C(=O)NCC34CC5CC(CC(C5)C3)C4)c2)CC1 -US04968829,1,CC(=O)COc1ccc(OCC=C(C)C)cc1.[NH4+]>>CC(C)=CCOc1ccc(OCC(C)N)cc1 -US08987319B2,6,COC(=O)C1CCCC1=O>>O=C(O)C1CCCC1=O -US05814648,7,CCOC(=O)COc1cccc(C2=N[C@@H](c3ccccc3)CO2)c1>>OCCOc1cccc(C2=N[C@@H](c3ccccc3)CO2)c1 -US20120108583A1,2,COC(=O)c1cc2nc(Nc3c(Cl)cncc3Cl)[nH]c2c2c1OC(C)(C)C2.Cc1ccc(N)c(Cl)c1>>Cc1ccc(NC(=O)c2cc3nc(Nc4c(Cl)cncc4Cl)[nH]c3c3c2OC(C)(C)C3)c(Cl)c1 -US07576098B2,6,CCOc1cc(O[Si](C)(C)C(C)(C)C)c(F)c(N(Cc2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(C#N)cc2)c1>>CCOc1cc(O)c(F)c(N(Cc2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(C#N)cc2)c1 -US20040192685A1,5,COc1ccc2c(c1)CCNC2C1CCCCC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2C1CCCCC1 -US20090253677A1,6,CCOC(=O)c1nc(C2(NC(=O)OCc3ccccc3)CCC3(CC2)OCCO3)[nH]c(=O)c1O>>CCOC(=O)c1nc(C2(NC(=O)OCc3ccccc3)CCC(=O)CC2)[nH]c(=O)c1O -US05610144,2,CC(C)OC(=O)C1CCC(c2ccccc2)N1.Cc1cccc(NC(=O)NCC(=O)O)c1>>Cc1cccc(NC(=O)NCC(=O)N2C(C(=O)OC(C)C)CCC2c2ccccc2)c1 -US05681961,6,CCOC(=O)C=C(c1cccnc1)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(C)cc1)C2>>Cc1ccc(S(=O)(=O)NC2Cc3ccc(C(=CC(=O)O)c4cccnc4)cc3C2)cc1 -US20050277670A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.N#Cc1ccc(N)cc1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(C#N)cc2)CC1 -US20130197009A1,6,COC(=O)c1ccc(CNC(=O)N2C[C@H](C)N(c3ccc(C#N)c(Cl)c3)C[C@H]2C)cc1>>C[C@H]1CN(C(=O)NCc2ccc(C(=O)O)cc2)[C@H](C)CN1c1ccc(C#N)c(Cl)c1 -US06919331B2,1,CC(C)CCn1c(CCl)nc2cc(CNC(=O)OC(C)(C)C)ccc21.O=C1Nc2ncccc2C1=NOCCF>>CC(C)CCn1c(CN2C(=O)C(=NOCCF)c3cccnc32)nc2cc(CNC(=O)OC(C)(C)C)ccc21 -US08481595B2,2,CC(=O)c1cccc(O)c1.Cc1cccc(C)c1C(=O)Cl>>CC(=O)c1cccc(OC(=O)c2c(C)cccc2C)c1 -US20070281937A1,7,CN(Cc1nc(C(=O)Nc2ccccc2)cn1-c1ccc(Cl)cc1)c1ccc(F)cc1>>CN(Cc1nc(CNc2ccccc2)cn1-c1ccc(Cl)cc1)c1ccc(F)cc1 -US07557213B2,1,BrCc1cccc(Br)n1.Cc1ccc(C(=O)c2c(C)[nH]c3ccccc3c2=O)cc1C>>Cc1ccc(C(=O)c2c(C)n(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1C -US20090156572A1,2,CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1.O=C1CCCC(C(=O)O)N1>>CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(C(=O)C2CCCC(=O)N2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US07572805B2,6,CC(C)(C)OC(=O)N1C[C@H]2c3cccc(C(F)(F)F)c3C(=O)N[C@@H]2C1>>O=C1N[C@@H]2CNCC2c2cccc(C(F)(F)F)c21 -US20010006969A1,1,C=CCNc1nc(Cl)nc2ccc([N+](=O)[O-])cc12.NC1CCCCC1>>C=CCNc1nc(NC2CCCCC2)nc2ccc([N+](=O)[O-])cc12 -US06369069B1,2,CN(C)C=NS(=O)(=O)c1ccccc1-c1ccc(CNCc2ccccc2)cc1.Cc1ccccc1CC(=O)Cl>>Cc1ccccc1CC(=O)N(Cc1ccccc1)Cc1ccc(-c2ccccc2S(=O)(=O)N=CN(C)C)cc1 -US20110002855A1,3,CN(C)C=O.Cn1ccc2cccnc21>>Cn1cc(C=O)c2cccnc21 -US05668161,4,CSc1ccc(C(Br)C(=O)c2ccccc2F)cc1.NC(=S)c1ccccc1Cl>>CSc1ccc(-c2sc(-c3ccccc3Cl)nc2-c2ccccc2F)cc1 -US20090062348A1,6,COCc1ccc(C(=O)OC)c(N)n1>>COCc1ccc(C(=O)O)c(N)n1 -US20150018547A1,1,CC(C)(C)OC(=O)CBr.CCOC(=O)c1sc2cc(OCc3ccc(Cl)cc3Cl)ccc2c1O>>CCOC(=O)c1sc2cc(OCc3ccc(Cl)cc3Cl)ccc2c1OCC(=O)OC(C)(C)C -US20100160255A1,6,CC(C)(C)OC(=O)Nc1sc(-c2ccncc2)cc1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1>>CC1(C)CC2(CCCN(C3CCN(C(=O)c4cc(-c5ccncc5)sc4N)CC3)C2)C(=O)O1 -US20090029976A1,6,COc1cc(OC)c(C(=O)c2ccc(F)cc2)cc1Cl>>COc1cc(O)c(C(=O)c2ccc(F)cc2)cc1Cl -US20140018371A1,2,CC(C)OC(=O)Cl.CS(=O)(=O)c1ccc(C2=CCC(OCC3CCNCC3)CC2)cc1>>CC(C)OC(=O)N1CCC(COC2CC=C(c3ccc(S(C)(=O)=O)cc3)CC2)CC1 -US08835488B2,3,COC(=O)CC#N.O=C1CCOC2(CCCC2)C1>>COC(=O)/C(C#N)=C1/CCOC2(CCCC2)C1 -US20140329803A1,1,CCOC(=O)N1CCCC(=O)CC1.N#CC1CCNCC1>>CCOC(=O)N1CCCC(N2CCC(C#N)CC2)CC1 -US08765730B2,1,CCCC(CC(=O)c1ccc(=O)[nH]c1)c1ccc(Br)cc1.CI>>CCCC(CC(=O)c1ccc(=O)n(C)c1)c1ccc(Br)cc1 -US07659279B2,2,COc1cc(OCC2CCNC2)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1.O=C(O)CO>>COc1cc(OCC2CCN(C(=O)CO)C2)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1 -US04003919,1,COC1(C)CCc2c(C)c(O)c(C)c(C)c2O1.ClCc1ccccc1>>COC1(C)CCc2c(C)c(OCc3ccccc3)c(C)c(C)c2O1 -US20150166480A1,2,CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)O)cc3F)cc2C#N)CC1.O[C@@H]1CCCNC1>>CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)N4CCC[C@@H](O)C4)cc3F)cc2C#N)CC1 -US03944589,6,CCOC(=O)Cc1ccc(C2=CCCCC2)cc1>>O=C(O)Cc1ccc(C2=CCCCC2)cc1 -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(O)cc(COC)c21>>COCc1cc(O)cc2c1C(CC(=O)O)OB2O -US20120295897A1,1,FC(F)(F)c1ccc(CBr)o1.O=C1Nc2ccccc2[C@@]12COc1cc3c(cc12)CCO3>>O=C1N(Cc2ccc(C(F)(F)F)o2)c2ccccc2[C@@]12COc1cc3c(cc12)CCO3 -US20150065705A1,1,ClCc1ccc(OCc2ccc(Cl)cc2)cc1.O=c1nc(N2CCN(c3ccc(F)cc3)CC2)[nH]c(=O)[nH]1>>O=c1nc(N2CCN(c3ccc(F)cc3)CC2)[nH]c(=O)n1Cc1ccc(OCc2ccc(Cl)cc2)cc1 -US08242273B2,6,CC(C)(C)Nc1nccc(C#C[Si](C)(C)C)n1>>C#Cc1ccnc(NC(C)(C)C)n1 -US20090306123A1,2,CCOC(=O)C(C)C(=O)C(F)(F)F.NO>>CC(C(=O)NO)C(=O)C(F)(F)F -US20080019930A1,2,CCCCC(CC)CO.O=C(O)CNC(=O)c1ccccc1>>CCCCC(CC)COC(=O)CNC(=O)c1ccccc1 -US04082751,7,CCCOc1ccc([N+](=O)[O-])cc1-c1ncc(-c2nnn[nH]2)c(=O)[nH]1>>CCCOc1ccc(N)cc1-c1ncc(-c2nnn[nH]2)c(=O)[nH]1 -US20110301122A1,1,CS(=O)(=O)OCc1ccc(Cl)nc1.Cc1cc(-c2nc(-c3ccc(C4(C(F)(F)F)CC4)cc3)no2)n[nH]1>>Cc1cc(-c2nc(-c3ccc(C4(C(F)(F)F)CC4)cc3)no2)nn1Cc1ccc(Cl)nc1 -US20090325902A1,2,CCN=C=O.Nc1cc(Br)c(I)cn1>>CCNC(=O)Nc1cc(Br)c(I)cn1 -US06472403B2,7,COC(=O)C1(c2cccnc2)CC1>>OCC1(c2cccnc2)CC1 -US20020107422A1,1,CC(=CCBr)CBr.O=C([O-])c1ccccc1>>CC(=CCOC(=O)c1ccccc1)CBr -US07915267B2,2,Cc1csc2nc(C(=O)NCc3cccc(CN)c3)[nH]c(=O)c12.O=C(O)c1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>Cc1csc2nc(C(=O)NCc3cccc(CNC(=O)c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)c3)[nH]c(=O)c12 -US20130296382A1,1,CI.N#Cc1cc(Cl)cc(Oc2c(C(F)(F)F)ccn(Cc3n[nH]c(=O)[nH]3)c2=O)c1>>Cn1c(Cn2ccc(C(F)(F)F)c(Oc3cc(Cl)cc(C#N)c3)c2=O)n[nH]c1=O -US20040006067A1,6,Cc1cc(C)c(S(=O)(=O)Nc2ccccc2C2CCN(C(=O)[C@@H](Cc3ccc(Cl)cc3)NC(=O)[C@@H]3Cc4ccccc4CN3C(=O)OC(C)(C)C)CC2)c(C)c1>>Cc1cc(C)c(S(=O)(=O)Nc2ccccc2C2CCN(C(=O)[C@@H](Cc3ccc(Cl)cc3)NC(=O)[C@@H]3Cc4ccccc4CN3)CC2)c(C)c1 -US04269788,2,CC(O)CC1(c2ccccc2)C=CCC=C1.CS(=O)(=O)Cl>>CC(CC1(c2ccccc2)C=CCC=C1)OS(C)(=O)=O -US20150158874A1,2,Nc1cncc(-c2ccc3ncnc(OC4CCOCC4)c3n2)c1.O=S(=O)(Cl)c1ccc(Br)cc1Br>>O=S(=O)(Nc1cncc(-c2ccc3ncnc(OC4CCOCC4)c3n2)c1)c1ccc(Br)cc1Br -US06248755B1,6,COc1ccc(COC(=O)[C@@H](C2CCCCC2)N2C[C@H](c3ccccc3)[C@@H](CN3CCC(c4ncc(Cc5ccccc5)s4)CC3)C2)cc1>>O=C(O)[C@@H](C1CCCCC1)N1C[C@H](c2ccccc2)[C@@H](CN2CCC(c3ncc(Cc4ccccc4)s3)CC2)C1 -US20050119269A1,3,CC(=O)c1ccc(OCCOc2c(-c3ccc(F)c(F)c3)n(C)c3ccccc3c2=O)c(Cl)c1.O=C1CSC(=O)N1>>CC(=C1SC(=O)NC1=O)c1ccc(OCCOc2c(-c3ccc(F)c(F)c3)n(C)c3ccccc3c2=O)c(Cl)c1 -US06514996B2,1,COc1ccc(C=O)c(Br)c1O.OC1C=CCCC1>>COc1ccc(C=O)c(Br)c1OC1C=CCCC1 -US20080146565A1,7,CSc1nccc(-n2ccc3c(C=O)cccc32)n1>>CSc1nccc(-n2ccc3c(CO)cccc32)n1 -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12.O=Cc1cccc2cnccc12>>FC(F)(F)c1nnc2ccc(N3CCN(Cc4cccc5cnccc45)CC3)nn12 -US20130296327A1,2,Cc1cc2c(cc1-c1cc(N3CCN(C)CC3)nc(N)n1)CNCC2.O=C=Nc1ccc(Cl)cc1>>Cc1cc2c(cc1-c1cc(N3CCN(C)CC3)nc(N)n1)CN(C(=O)Nc1ccc(Cl)cc1)CC2 -US20070254869A1,2,CO.O=C(O)c1ccc(Br)cc1[N+](=O)[O-]>>COC(=O)c1ccc(Br)cc1[N+](=O)[O-] -US20080318947A1,1,CCn1c(-c2nonc2N)nc2c(Cl)nc(CO)cc21.O=C1NC(=O)c2ccccc21>>CCn1c(-c2nonc2N)nc2c(Cl)nc(CN3C(=O)c4ccccc4C3=O)cc21 -US20040242572A1,1,CC(C)NC(C)C.O=C(NCCc1ccc(CBr)cc1)c1ccc(-c2ccc(Cl)cc2)cc1>>CC(C)N(Cc1ccc(CCNC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cc1)C(C)C -US20050176775A1,2,CN.Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1ccc(C(=O)O)o1>>CNC(=O)c1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)o1 -US03971800,6,CCOC(=O)c1c(C)nc(OCC)c2nnn(CC)c12>>CCOc1nc(C)c(C(=O)O)c2c1nnn2CC -US20090093524A1,1,CC(C)c1nnn(-c2c(Cl)cccc2Cl)c1CO.Cc1cc(O)ccc1Br>>Cc1cc(OCc2c(C(C)C)nnn2-c2c(Cl)cccc2Cl)ccc1Br -US07649001B2,3,C=C(C)Cc1c(OC)cccc1OCOC.CN(C)C=O>>C=C(C)Cc1c(OC)ccc(C=O)c1OCOC -US20110319426A1,9,COc1c(C)cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)c3c(F)cccc32)cc1CBr.[C-]#N>>COc1c(C)cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)c3c(F)cccc32)cc1CC#N -US08802659B2,1,CC(C)(C)[C@@H]1CC[C@H](O)CC1.Oc1ccc2cc(Br)ccc2n1>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(Br)ccc3n2)CC1 -US07803819B2,6,Cc1cc(-c2ccccc2)nn1CCC(C)(C)NC(=O)OC(C)(C)C>>Cc1cc(-c2ccccc2)nn1CCC(C)(C)N -US20080312192A1,1,CCCC[Sn](Cl)(CCCC)CCCC.Cc1cccc(Br)n1>>CCCC[Sn](CCCC)(CCCC)c1cccc(C)n1 -US20070054936A1,3,Cc1cc(C)c([Mg+])c(C)c1.N#Cc1cccc(-c2ccncc2C=O)c1>>Cc1cc(C)c(C(O)c2cnccc2-c2cccc(C#N)c2)c(C)c1 -US20120129875A1,8,COc1ccc(-c2ncccc2C)cc1F.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2c(C)ccc[n+]2[O-])cc1F -US04782149,6,CC(=O)O[C@H](CCc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@H](O)CCc1ccc([N+](=O)[O-])cc1 -US08153818B2,2,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(Cl)cc1C(=O)O>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)O)cc1 -US20110313151A1,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CC=O)CC1.c1cc2sccc2c(N2CCNCC2)n1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4sccc34)CC2)CC1 -US20140142097A1,3,CC(C)(C)OC(=O)Nc1cccc(B(O)O)c1.Nc1ncc(Br)cc1C(=O)Nc1ccncc1>>CC(C)(C)OC(=O)Nc1cccc(-c2cnc(N)c(C(=O)Nc3ccncc3)c2)c1 -US05451677,2,Nc1ccc(CCNC(=O)OCc2ccccc2)cc1.O=S(=O)(Cl)c1ccccc1>>O=C(NCCc1ccc(NS(=O)(=O)c2ccccc2)cc1)OCc1ccccc1 -US20070270587A1,6,CC1(C)CN=C2N(C1)c1ccc(S(=O)(=O)N3CCCC3)cc1C21OCCCO1>>CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCCC4)ccc3N2C1 -US20150203483A1,1,C1COCCN1.CNC(=O)N1N=C(c2ccc(Br)cc2)c2cc(OC)c(OC)cc2CC1C>>CNC(=O)N1N=C(c2ccc(N3CCOCC3)cc2)c2cc(OC)c(OC)cc2CC1C -US20070032508A1,1,CN(C)CC(=O)N1CCC(Oc2ccc3ncnc(Cl)c3c2)CC1.Nc1ccc(O)cc1>>CN(C)CC(=O)N1CCC(Oc2ccc3ncnc(Nc4ccc(O)cc4)c3c2)CC1 -US20070043065A1,6,Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccc(N3CCN(CC(=O)OC(C)(C)C)CC3)cc2c1=O>>Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccc(N3CCN(CC(=O)O)CC3)cc2c1=O -US06822100B2,1,CNC.O=CC1CC1c1ccc2cc[nH]c2c1>>CN(C)CC1CC1c1ccc2cc[nH]c2c1 -US20130317021A1,7,O=C(NCCc1ccc(Cl)cc1)c1cc([N+](=O)[O-])[nH]n1>>Nc1cc(C(=O)NCCc2ccc(Cl)cc2)n[nH]1 -US20140171390A1,1,COC(=O)CC1CC(=O)C1.COc1ccc(CN)c(OC)c1>>COC(=O)CC1CC(NCc2ccc(OC)cc2OC)C1 -US20120302566A1,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)cccc43)ccc21.COc1nccc(C(F)(F)F)c1I>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C(F)(F)F)ccnc5OC)cccc43)ccc21 -US20130178459A1,1,BrCc1ccc(Br)cc1.CCN>>CCNCc1ccc(Br)cc1 -US08431695B2,3,CC(C)(C)OC(=O)N1CCC(c2cc(Br)c3c(N)ncnn23)CC1.CC1(C)OB(c2ccc3nc(Cc4ccccc4)sc3c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(c2cc(-c3ccc4nc(Cc5ccccc5)sc4c3)c3c(N)ncnn23)CC1 -US20070179173A1,3,O=C1CSC(=O)N1.O=Cc1ccc(O)c2c1CCC(=O)N2Cc1ccccc1>>O=C1NC(=O)C(=Cc2ccc(O)c3c2CCC(=O)N3Cc2ccccc2)S1 -US04356186,2,C=CCO.CC(C(=O)O)c1ccc2c(c1)SCC1CCCCC1C2=O>>C=CCOC(=O)C(C)c1ccc2c(c1)SCC1CCCCC1C2=O -US08536214B2,7,COC(=O)c1ccc2c(c1)C[C@@H](NC(=O)OCc1ccccc1)C2>>O=C(N[C@H]1Cc2ccc(CO)cc2C1)OCc1ccccc1 -US07259183B2,1,CC1(C)CCc2cc(C=O)ccc21.NCCc1cccc(C(F)(F)F)c1>>CC1(C)CCc2cc(CNCCc3cccc(C(F)(F)F)c3)ccc21 -US04853469,6,CC(=O)NC1CCN(Cc2ccccc2)C1>>CC(=O)NC1CCNC1 -US20090170791A1,6,CCOC(=O)c1cn(N(C)C)c2ccc(I)cc2c1=O>>CN(C)n1cc(C(=O)O)c(=O)c2cc(I)ccc21 -US04925834,3,CSC[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]12.FC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CSC[C@]12CCC(=CF)C=C1CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]12 -US20050090541A1,6,COc1ccc2c(c1)C(=C(C)c1ccc[nH]1)C(=O)N2>>CC(=C1C(=O)Nc2ccc(O)cc21)c1ccc[nH]1 -US04405552,6,CCOC(=O)c1cc(-c2ccc(Cl)cc2)c(Cl)nc1N>>Nc1nc(Cl)c(-c2ccc(Cl)cc2)cc1C(=O)O -US20110237573A1,2,Cc1cc(-c2ccc(CC(=O)O)cc2C#N)ccn1.Nc1ccc(-c2cccnn2)cn1>>Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cccnn4)cn3)cc2C#N)ccn1 -US20140121198A1,2,CC(=O)OC(C)=O.C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@@H]1CC[C@@H](CN)CC1>>CC(=O)NC[C@@H]1CC[C@@H](n2c([C@@H](C)O)nc3cnc4ccsc4c32)CC1 -US20030236250A1,7,CC(C)(C)OC(=O)N1CCC(CCCO)(C(=O)OCc2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(CCCO)CC1 -US20070244334A1,4,CCC/C=C/C(=O)O.O=S([O-])OO>>CCCC1OC1C(=O)O -US20060270628A1,1,O=[N+]([O-])c1ccc(F)c(F)c1.c1c[nH]cn1>>O=[N+]([O-])c1ccc(-n2ccnc2)c(F)c1 -US04075227,3,COc1ccc2c(-c3ccccc3)csc2c1.COc1ccccc1C(=O)Cl>>COc1ccc2c(-c3ccccc3)c(C(=O)c3ccccc3OC)sc2c1 -US08119627B2,1,O=[N+]([O-])c1ccccc1F.Oc1cc(Cl)cc(Cl)c1>>O=[N+]([O-])c1ccccc1Oc1cc(Cl)cc(Cl)c1 -US06576653B2,2,N[C@@H](Cc1ccccc1)C(=O)N1CC(O)C1.O=C(O)c1cc2cc(Br)sc2[nH]1>>O=C(N[C@@H](Cc1ccccc1)C(=O)N1CC(O)C1)c1cc2cc(Br)sc2[nH]1 -US09096595B2,9,CC(C)(C)OC(=O)C1C(=O)CCc2cc3ccccc3n21>>O=C1CCc2cc3ccccc3n2C1 -US20130040931A1,1,COc1ccc(CN)cc1.Clc1nc2ccc(Br)cc2cc1I>>COc1ccc(CNc2nc3ccc(Br)cc3cc2I)cc1 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.Cc1ccc(C(=O)O)s1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)c4ccc(C)s4)nc3cc21 -US20130059853A1,1,COc1ccc(-c2ccc3c(c2)COC3=O)c(OC)c1O.OCC1(CBr)COC1>>COc1ccc(-c2ccc3c(c2)COC3=O)c(OC)c1OCC1(CO)COC1 -US04425333,2,CC(=O)SCCC(=O)N1[C@H](C(=O)O)CS[C@@H]1c1ccccc1O.O=C(O)[C@@H]1CCCN1>>CC(=O)SCCC(=O)N1[C@H](C(=O)N2CCC[C@H]2C(=O)O)CS[C@@H]1c1ccccc1O -US20150080373A1,1,COc1ccc2ncc(C(=O)OC[C@@H]3CC[C@@H](N)CC3)cc2c1.O=Cc1ccc2c(c1)OCCO2>>COc1ccc2ncc(C(=O)OC[C@@H]3CC[C@@H](NCc4ccc5c(c4)OCCO5)CC3)cc2c1 -US08299267B2,3,C=C(C)Br.OB(O)c1cc(Br)cc(Br)c1>>C=C(C)c1cc(Br)cc(Br)c1 -US20110184177A1,6,CCOC(=O)C(C)(CC)NC(=O)c1cc(Cl)c2ccccc2c1OCC1CCN(C(=O)OC(C)(C)C)CC1>>CCC(C)(NC(=O)c1cc(Cl)c2ccccc2c1OCC1CCN(C(=O)OC(C)(C)C)CC1)C(=O)O -US20040048916A1,1,CC(C)Br.CC(C)CN1C(=O)c2ccc(O)cc2C1=O>>CC(C)CN1C(=O)c2ccc(OC(C)C)cc2C1=O -US20120142681A1,3,C=C[Sn](CCCC)(CCCC)CCCC.Cn1ncc2cc(Cc3cnc4ccc(Cl)nn34)c(F)cc21>>C=Cc1ccc2ncc(Cc3cc4cnn(C)c4cc3F)n2n1 -US05166210,1,ClCc1ccc2ccccc2n1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCc2ccc3ccccc3n2)cc1 -US08129371B2,2,CC(C)n1ncc(C#N)c1N.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC(C)n1ncc(C#N)c1NC(=O)c1ccc([N+](=O)[O-])cc1 -US20020091252A1,2,NNN=CN1CCNCC1.O=CO>>NNN=CN1CCN(C=O)CC1 -US04168964,1,CC(=O)c1nc(-c2ccccc2)[nH]c1C.COC(=O)NN>>COC(=O)NN=C(C)c1nc(-c2ccccc2)[nH]c1C -US20150133438A1,6,O=C(NC1=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](c3ncco3)C[C@H]2CS1)c1ccccc1>>NC1=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](c3ncco3)C[C@H]2CS1 -US05292732,4,CC(=O)NCCN.O=CCC1CCc2c(Cl)cccc2C1=O>>CC(=O)NCCn1ccc2c1-c1cccc(Cl)c1CC2 -US20100144722A1,6,CNc1cc(-c2ccccc2)nc(Nc2ccc(C3(C(=O)OC)CCC3)cc2)n1>>CNc1cc(-c2ccccc2)nc(Nc2ccc(C3(C(=O)O)CCC3)cc2)n1 -US08796447B2,7,CNc1cccc(OCc2ccccc2)c1[N+](=O)[O-]>>CNc1cccc(OCc2ccccc2)c1N -US20050107449A1,7,CCOC(=O)C(C)c1nc(-c2ccc(-c3ccccc3F)nc2)sc1C>>Cc1sc(-c2ccc(-c3ccccc3F)nc2)nc1C(C)CO -US08044063B2,7,O=[N+]([O-])c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1>>Nc1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1 -US08030354B2,1,COC(=O)CCc1cccc(O)c1.Cc1cc(CCl)ccc1Br>>COC(=O)CCc1cccc(OCc2ccc(Br)c(C)c2)c1 -US20040138199A1,3,CC(C)(C)OC(=O)N1CCOc2ccc(Br)cc21.CN(C)C=O>>CC(C)(C)OC(=O)N1CCOc2ccc(C=O)cc21 -US07915300B2,4,NC(=S)N1CCCCC1.O=C(O)c1ccc(C(=O)CBr)cc1>>O=C(O)c1ccc(-c2csc(N3CCCCC3)n2)cc1 -US20120077812A1,7,CC(=O)c1ccncc1>>C[C@@H](O)c1ccncc1 -US06933311B2,2,Cn1ncc2c(N)cccc21.O=C=NCc1ccc(N2CCCCCC2)c(F)c1>>Cn1ncc2c(NC(=O)NCc3ccc(N4CCCCCC4)c(F)c3)cccc21 -US07858796B2,1,C1CCNC1.NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)c[nH]c12>>NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCN4CCCC4)CC3)c[nH]c12 -US20130122506A1,3,CCCC[Sn](CCCC)(CCCC)c1cccs1.O=[N+]([O-])c1cc(I)cn1[C@H]1C[C@H](O)[C@@H](CO)O1>>O=[N+]([O-])c1cc(-c2cccs2)cn1[C@H]1C[C@H](O)[C@@H](CO)O1 -US20120065066A1,3,C1=CCC=C1.O=C1C=CC(=O)C1>>O=C1CC(=O)C2C3C=CC(C3)C12 -US20060122224A1,2,CC(=O)Cl.CCOC(=O)N1c2ccc(C(F)(F)F)cc2C([C@@H](CO)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)=C[C@H]1CC>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2C([C@H](COC(C)=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)=C[C@H]1CC -US20080004271A1,2,Nc1cccc(C2OCCO2)c1.O=C=Nc1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)Nc1cccc(C2OCCO2)c1 -US20030199570A1,1,CI.O=[N+]([O-])c1ccc(O)cc1C(F)(F)F>>COc1ccc([N+](=O)[O-])c(C(F)(F)F)c1 -US20140228361A1,1,C1CC2CNCC2C1.ClCCCBr>>ClCCCN1CC2CCCC2C1 -US20150191461A1,2,COC(=O)C1CCC(O)CC1(C)C.CS(=O)(=O)Cl>>COC(=O)C1CCC(OS(C)(=O)=O)CC1(C)C -US20130053404A1,3,CC(C)c1nc2c(c(I)c1C=O)[C@@H](O[Si](C)(C)C(C)(C)C)CC(C)(C)C2.[Mg+]c1ccc(OCc2ccccc2)cc1>>CC(C)c1nc2c(c(I)c1[C@@H](O)c1ccc(OCc3ccccc3)cc1)[C@@H](O[Si](C)(C)C(C)(C)C)CC(C)(C)C2 -US20110118236A1,10,CCOC(=O)c1sc(SC)c(C(=O)OCC)c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1sc(SC)c(C(=O)OCC)c1CBr -US08901141B2,9,CCc1nc(C)nc(CC)c1N.S=C(Cl)Cl>>CCc1nc(C)nc(CC)c1N=C=S -US07071337B2,6,COc1ccc2c(c1)ncn2-c1ccc2cccc(N3CCC(N)CC3)c2n1>>NC1CCN(c2cccc3ccc(-n4cnc5cc(O)ccc54)nc23)CC1 -US05102667,2,C[C@@H](C(=O)O)c1ccccc1.O=C1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12>>C[C@@H](C(=O)N1C[C@@H]2C(=O)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1)c1ccccc1 -US20040176608A1,3,CC(C)Oc1ccccc1-c1ccccc1.CN(C)C=O>>CC(C)Oc1c(C=O)cccc1-c1ccccc1 -US20100204212A1,9,COc1ccc(CN(c2ccccc2)c2cc(Cl)nn3c(Br)cnc23)cc1.[C-]#N>>COc1ccc(CN(c2ccccc2)c2cc(Cl)nn3c(C#N)cnc23)cc1 -US08269008B2,6,CCOC(=O)c1nc(C#C[Si](C)(C)C)c2c(-c3ccccc3)noc2c1O>>C#Cc1nc(C(=O)OCC)c(O)c2onc(-c3ccccc3)c12 -US20090270434A1,3,C#CC(C)(C)O.Fc1ccc(Br)c(OC2CCN(c3ncc(Br)cn3)CC2)c1>>CC(C)(O)C#Cc1cnc(N2CCC(Oc3cc(F)ccc3Br)CC2)nc1 -US08106077B2,1,CC(C)c1nnn(-c2c(Cl)cccc2Cl)c1CO.COC(=O)c1ccc(NCc2ccc(O)cc2C)cc1>>COC(=O)c1ccc(NCc2ccc(OCc3c(C(C)C)nnn3-c3c(Cl)cccc3Cl)cc2C)cc1 -US20100144745A1,2,CCS(=O)(=O)Cl.C[Si](C)(C)CCOCn1ccc2nc(NC(=O)NC3CCCNC3)cnc21>>CCS(=O)(=O)N1CCCC(NC(=O)Nc2cnc3c(ccn3COCC[Si](C)(C)C)n2)C1 -US20120116077A1,1,CCOC(=O)C(C)(C=O)CCC(C)C.NC1CCCC1>>CCOC(=O)C(C)(CCC(C)C)CNC1CCCC1 -US07579353B2,1,CCCC[Sn](Cl)(CCCC)CCCC.FC(F)(F)c1ccc(-c2ncc(Br)cn2)cc1>>CCCC[Sn](CCCC)(CCCC)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1 -US07847100B2,3,CC(C)(C)OC(=O)N1CCC[C@@H]1C=O.CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C/C=C\[C@H]1CCCN1C(=O)OC(C)(C)C -US20080234306A1,8,CCO[C@@]12CCC(=O)[C@@H]3Oc4c(O)ccc5c4[C@@]31CCN(CC1CC1)[C@@H]2C5.O=C(OO)c1cccc(Cl)c1>>CCO[C@@]12CCC(=O)[C@@H]3Oc4c(O)ccc5c4[C@@]31CC[N+]([O-])(CC1CC1)[C@@H]2C5 -US20110046169A1,2,Cn1cc(C(=O)O)c(=O)n1-c1c(Cl)cccc1Cl.Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3c2)c(F)c1>>Cn1cc(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c(F)c2)c(=O)n1-c1c(Cl)cccc1Cl -US09120804B2,2,COc1cc(Nc2nc3c(N4CCNCC4)nccn3n2)cc(OC)c1.CS(=O)(=O)Cl>>COc1cc(Nc2nc3c(N4CCN(S(C)(=O)=O)CC4)nccn3n2)cc(OC)c1 -US20050119320A1,2,CC(C)(C)[Si](OC1CNC1)(c1ccccc1)c1ccccc1.Cc1nc(N=C=O)sc1-c1ccc(Cl)c(S(C)(=O)=O)c1>>Cc1nc(NC(=O)N2CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C2)sc1-c1ccc(Cl)c(S(C)(=O)=O)c1 -US20100041892A1,2,CCCCCS(N)(=O)=O.O=C(O)/C=C/c1ccc(OCCOC2CC2)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC2CC2)cc1Oc1ncc(C(F)(F)F)cc1Cl -US20140142114A1,1,C1CNCCN1.FC(F)(F)c1ccc2c(c1)CC(CI)O2>>FC(F)(F)c1ccc2c(c1)CC(CN1CCNCC1)O2 -US20090036495A1,2,COC(=O)c1ccc(CN)cc1.O=C(O)c1cc(Cl)ccc1Oc1ccc(F)cc1>>COC(=O)c1ccc(CNC(=O)c2cc(Cl)ccc2Oc2ccc(F)cc2)cc1 -US20110009622A1,2,Nc1ccc(Oc2ccccc2)nc1.O=C(O)c1cccc(S(=O)(=O)N2CCCCC2)c1>>O=C(Nc1ccc(Oc2ccccc2)nc1)c1cccc(S(=O)(=O)N2CCCCC2)c1 -US20150087626A1,2,COC(=O)c1ccc([C@H](C)N)cc1.O=C(O)C1CCN1Cc1ccccc1>>COC(=O)c1ccc([C@H](C)NC(=O)C2CCN2Cc2ccccc2)cc1 -US06310243B1,2,CC(=O)OCC(COC(C)=O)(COC(C)=O)C(=O)Cl.CC(=O)OCc1c(I)c(N)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I>>CC(=O)OCc1c(I)c(NC(=O)C(COC(C)=O)(COC(C)=O)COC(C)=O)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I -US05521177,1,CCCc1nc2c(C)cc(N3C(=O)c4ccccc4C3=O)cc2[nH]1.COC(=O)c1ccccc1-c1ccc(CBr)cc1>>CCCc1nc2c(C)cc(N3C(=O)c4ccccc4C3=O)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1 -US20120251545A1,6,COc1ccc(CN2Cc3cc(Cl)c(OC)cc3C2)cc1>>COc1cc2c(cc1Cl)CNC2 -US20130261106A1,6,CC(=O)OC1CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)OC1CCNCC1 -US20130085164A1,3,CC[Mg+].COCOCc1ccc(-c2ccc(C=O)nc2)cc1>>CCC(O)c1ccc(-c2ccc(COCOC)cc2)cn1 -US04841062,6,CCOC(=O)C(=NOC1CCCCC1)c1csc(N)n1>>Nc1nc(C(=NOC2CCCCC2)C(=O)O)cs1 -US05037990,1,NCCc1cccc(O)c1.O=Cc1ccccc1>>Oc1cccc(CCNCc2ccccc2)c1 -US20100144710A1,8,CCCCOc1ccc(C)nc1.O=C(OO)c1cccc(Cl)c1>>CCCCOc1ccc(C)[n+]([O-])c1 -US20070082934A1,9,[NH3+]c1nc(-c2ccc(Oc3ccc(Cl)cc3)cc2)cs1>>[NH3+]c1nc(-c2ccc(Oc3ccccc3)cc2)cs1 -US20150191431A1,2,N[C@@H]1CC[C@@H](Oc2ccnc3ccccc23)CC1.O=C(Cl)c1ccc(F)c(F)c1>>O=C(N[C@@H]1CC[C@@H](Oc2ccnc3ccccc23)CC1)c1ccc(F)c(F)c1 -US20100190814A1,2,CC(C)C(=O)Cl.CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)NS(C)(=O)=O>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)N(C(=O)C(C)C)c1cc(Cl)ccc12)C(=O)NS(C)(=O)=O -US06288242B1,3,CC(C)(C)COC(=O)c1ccc(C(F)(F)F)cc1B(O)O.O[C@H]1c2ccc(Br)cc2OC[C@@H]1Cc1ccccc1>>CC(C)(C)COC(=O)c1ccc(C(F)(F)F)cc1-c1ccc2c(c1)OC[C@H](Cc1ccccc1)[C@H]2O -US06579868B1,7,CCn1c(-c2cccc(F)c2)nc2c(N)nc(C#CC(C)(C)O)nc21>>CCn1c(-c2cccc(F)c2)nc2c(N)nc(/C=C\C(C)(C)O)nc21 -US20140148508A1,10,C[C@H]1C(=O)O[C@@H]2CC=C[C@H]12.O>>C[C@H]1C(=O)O[C@@H]2C[C@H](O)C[C@H]12 -US05420135,1,Cc1ccccc1N.O=[N+]([O-])c1cnc2ccccc2c1Cl>>Cc1ccccc1Nc1c([N+](=O)[O-])cnc2ccccc12 -US20120094917A1,2,COC(=O)C1CNC2CCN(C(=O)C(NC(=O)OC(C)(C)C)C3CCCCC3)C21.O=C(Cl)C1CC1>>COC(=O)C1CN(C(=O)C2CC2)C2CCN(C(=O)C(NC(=O)OC(C)(C)C)C3CCCCC3)C12 -US20110212956A1,2,CC1NCCc2cc(F)c(F)cc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2cc(F)c(F)cc2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US04532333,7,N#Cc1cccc(CN2CCc3cc(Cl)ccc32)c1>>NCc1cccc(CN2CCc3cc(Cl)ccc32)c1 -US07388025B2,1,CC(C)NC(=O)CCl.Cc1onc(-c2ccccc2)c1C(=O)c1cc2cccc(O)c2o1>>Cc1onc(-c2ccccc2)c1C(=O)c1cc2cccc(OCC(=O)NC(C)C)c2o1 -US20140378462A1,3,CCCC[Sn](/C=C\CN(CC)CC)(CCCC)CCCC.COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2Br)ccc2c1OCc1nnccc1-2>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)OCc1nnccc1-2 -US20130231328A1,1,CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(N)=O)CC4)CC1.O=C(CCl)N1CCCC1>>CN(CC(=O)N1CCCC1)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(N)=O)CC4)CC1 -US08623866B2,2,COC(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1.NC1CCCCC1>>Cn1cc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)c(C(=O)NC2CCCCC2)n1 -US06448293B1,6,COC(=O)c1ccc(Oc2ccc(SC)cc2)c(CN(C)C)c1>>CSc1ccc(Oc2ccc(C(=O)O)cc2CN(C)C)cc1 -US07799800B2,2,CCCCCCCCCCCCCCCC(=O)Cl.COCCc1nc2c(N)nc3ccccc3c2n1CCOCCN>>CCCCCCCCCCCCCCCC(=O)NCCOCCn1c(CCOC)nc2c(N)nc3ccccc3c21 -US20030171377A1,6,COC(=O)CCn1ccc2cc(OCc3ccccc3)ccc21>>COC(=O)CCn1ccc2cc(O)ccc21 -US08981084B2,2,Fc1ccccc1N1CCNCC1.O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1>>O=C(c1cccc(-c2noc(C(F)(F)F)n2)c1)N1CCN(c2ccccc2F)CC1 -US20050234029A1,3,Fc1ccc(-c2nc3ccccn3c2-c2ccnc(Br)c2)cc1Cl.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2cc(-c3c(-c4ccc(F)c(Cl)c4)nc4ccccn34)ccn2)cc1 -US04064257,2,C#CCCCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>C#CCCCCOS(=O)(=O)c1ccc(C)cc1 -US20150218113A1,1,CC1(C)Oc2cc(N(S(C)(=O)=O)S(C)(=O)=O)ccc2NC1=O.Fc1ccc(B2OB(c3ccc(F)cc3)OB(c3ccc(F)cc3)O2)cc1>>CC1(C)Oc2cc(N(S(C)(=O)=O)S(C)(=O)=O)ccc2N(c2ccc(F)cc2)C1=O -US07053083B2,6,CN1c2ccccc2CN(C(=O)C(F)(F)F)c2ccccc21>>CN1c2ccccc2CNc2ccccc21 -US05006556,2,CNC.O=C(Cl)COc1ccc(I)cc1>>CN(C)C(=O)COc1ccc(I)cc1 -US20150266822A1,1,Brc1nccs1.COC(=O)c1cc(O)cc(-c2ccc(C)cn2)c1>>COC(=O)c1cc(Oc2nccs2)cc(-c2ccc(C)cn2)c1 -US06982348B2,6,CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(Oc2ccc(Cl)c(CC)c2)cc1>>CCc1cc(Oc2ccc(C(O)C(Cc3cccc(OC(F)(F)C(F)F)c3)C(=O)O)cc2)ccc1Cl -US07888352B2,7,O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>OCc1cc2nc(Cl)nc(N3CCOCC3)c2s1 -US05098892,2,CC(C)(C)OC(=O)CNC1Cc2ccccc2C1.CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)CN(C(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)C1Cc2ccccc2C1 -US20080255085A1,3,COc1ccc(B(O)O)cc1.O=C(NCCN1CCOCC1)c1ccc(-c2nc3c(Cl)ccnc3[nH]2)cc1>>COc1ccc(-c2ccnc3[nH]c(-c4ccc(C(=O)NCCN5CCOCC5)cc4)nc23)cc1 -US20140249137A1,9,CC(C)(C)NS(=O)(=O)c1cccc(Br)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)NS(=O)(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1 -US05840732,2,NCCCn1c(=O)c(-c2ccccc2)c2n(c1=O)CCCS2(=O)=O.O=C(O)Cc1cccc2nccn12>>O=C(Cc1cccc2nccn12)NCCCn1c(=O)c(-c2ccccc2)c2n(c1=O)CCCS2(=O)=O -US07365066B2,1,CO.Clc1cccc(-c2nn3ccccc3c2-c2ccnc3ccccc23)n1>>COc1cccc(-c2nn3ccccc3c2-c2ccnc3ccccc23)n1 -US20120157436A1,2,CC(C)(C)OC(=O)NN.Cc1cnc(C(=O)O)s1>>Cc1cnc(C(=O)NNC(=O)OC(C)(C)C)s1 -US20140243302A1,1,COc1ccc2ncc(F)c(CC(O)C34CCC(N)(CC3)CO4)c2n1.O=Cc1ccc2c(n1)NC(=O)CS2>>COc1ccc2ncc(F)c(CC(O)C34CCC(NCc5ccc6c(n5)NC(=O)CS6)(CC3)CO4)c2n1 -US20050159407A1,2,CC(C)(C)OC(=O)C(N)CC(=O)OCc1ccccc1.COc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(S(=O)(=O)NC(CC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)cc1 -US04022792,1,C=O.COc1ccc(CC2NCCCC2=C(C)C)cc1>>COc1ccc(CC2C(=C(C)C)CCCN2C)cc1 -US08252930B2,1,CO.c1cnc2[nH]c(CC3CCNC3)cc2c1>>CN1CCC(Cc2cc3cccnc3[nH]2)C1 -US06770667B1,2,Cc1cn(-c2cccc(N)c2)cn1.O=C(O)c1cccc2c1Cc1ccccc1-2>>Cc1cn(-c2cccc(NC(=O)c3cccc4c3Cc3ccccc3-4)c2)cn1 -US05112825,2,CCOC(=O)CCC1CCNCC1.O=C(Cl)OCc1ccccc1>>CCOC(=O)CCC1CCN(C(=O)OCc2ccccc2)CC1 -US20070219210A1,1,CO.Oc1ccc(Cl)nc1>>COc1ccc(Cl)nc1 -US06444679B1,6,CCN(CC)C(=O)c1cnc(C2(c3cccc(O)c3)CCN(Cc3ccccc3)CC2)nc1>>CCN(CC)C(=O)c1cnc(C2(c3cccc(O)c3)CCNCC2)nc1 -US20150031674A1,8,CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CC[C@H]3COC(C)(C)O3)c2n1.O=C(OO)c1cccc(Cl)c1>>Cc1cncc(-c2ccc(-c3cc4cnc(S(C)=O)nc4n(CC[C@H]4COC(C)(C)O4)c3=O)c(Cl)c2)n1 -US04668397,9,COC(=O)[C@@H]1CCCN1C(=O)CN(C)C(=O)[C@@](N)(CCCC(N)C(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>COC(=O)[C@@H]1CCCN1C(=O)CN(C)C(=O)[C@@H](N)CCCC(N)C(=O)OCc1ccccc1 -US20150141427A1,3,CC1(C)OB(c2cncnc2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCO)c(Br)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCO)c(-c2cncnc2)c1 -US08293735B2,3,CN(C)C=O.Clc1nc(N2CCOCC2)c2sccc2n1>>O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1 -US20140058125A1,3,C#Cc1ccccc1.CCOC(=O)CCc1ccc(Br)cc1F>>CCOC(=O)CCc1ccc(C#Cc2ccccc2)cc1F -US20150051197A1,1,N#Cc1cccc(Br)c1.O=S1(=O)CCN2C(=N1)C1(c3ccc(O)cc3)CCC2CC1>>N#Cc1cccc(Oc2ccc(C34CCC(CC3)N3CCS(=O)(=O)N=C34)cc2)c1 -US08906941B2,2,NC(=O)C(O)C(N)Cc1ccccc1.O=C(O)c1cccnc1-c1nc(-c2ccc(F)cc2)cs1>>NC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-c1nc(-c2ccc(F)cc2)cs1 -US20100160309A1,6,CC(C)(C)OC(=O)N1CC[C@@H](Nc2nc3c(C#CC4CC4)c[nH]c(=O)c3c3cc(F)ccc23)[C@H](F)C1>>O=c1[nH]cc(C#CC2CC2)c2nc(N[C@@H]3CCNC[C@H]3F)c3ccc(F)cc3c12 -US20090221555A1,1,CN(C)S(=O)(=O)c1cc(C(F)(F)F)ccc1Cl.NCc1ccccc1>>CN(C)S(=O)(=O)c1cc(C(F)(F)F)ccc1NCc1ccccc1 -US20140073634A1,3,COCCOc1cccc(Cn2cc(-c3noc(-c4ccc(Br)cc4)n3)ccc2=O)c1.OB(O)C1CC1>>COCCOc1cccc(Cn2cc(-c3noc(-c4ccc(C5CC5)cc4)n3)ccc2=O)c1 -US04350817,5,CCOC(=O)c1c(N)c2cccnc2n(CC)c1=O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1c(NC(=O)C(F)(F)F)c2cccnc2n(CC)c1=O -US07576100B2,1,CCCOC1CCNCC1.C[C@H](CI)Cn1c(=O)ccc2ccccc21>>CCCOC1CCN(C[C@@H](C)Cn2c(=O)ccc3ccccc32)CC1 -US08552181B2,3,COC(=O)[C@@H](CI)C(=O)OC(C)(C)C.FC(F)(F)c1nccc(Cl)n1>>COC(=O)[C@H](Cc1ccnc(C(F)(F)F)n1)C(=O)OC(C)(C)C -US20120214858A1,2,N#CC1(C(=O)O)CC1.Nc1ccc(CCCCCCCCc2ccccc2)cc1>>N#CC1(C(=O)Nc2ccc(CCCCCCCCc3ccccc3)cc2)CC1 -US07452909B2,1,Cc1ccc(CCl)cn1.Cc1nc(C#Cc2cccc(Cl)c2)c[nH]1>>Cc1ccc(Cn2cc(C#Cc3cccc(Cl)c3)nc2C)cn1 -US20100240702A1,6,COC(=O)CCn1c(=O)n(Cc2cc(Cl)cc3c2CC(=O)N3)c2ccccc21>>O=C(O)CCn1c(=O)n(Cc2cc(Cl)cc3c2CC(=O)N3)c2ccccc21 -US20110301211A1,3,CCOC(=O)c1ccc(B(O)O)cc1.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)O[C@H](C)c1ccccc1Cl>>CCOC(=O)c1ccc(-c2ccc(-c3onc(C)c3NC(=O)O[C@H](C)c3ccccc3Cl)cc2)cc1 -US20050176775A1,1,COC(=O)c1cccc(-n2c(COC(C)=O)cc(O)c(Br)c2=O)c1.Fc1ccc(CBr)c(F)c1>>COC(=O)c1cccc(-n2c(COC(C)=O)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1 -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccccc3)cc2n(Cc2ccc(S(C)(=O)=O)cc2)c1=O.NCCN1CCCC1>>CS(=O)(=O)c1ccc(Cn2c(=O)c(C(=O)NCCN3CCCC3)c(O)c3ncc(Cc4ccccc4)cc32)cc1 -US20080070948A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CCO)CC1 -US20140288123A1,6,COC(=O)c1ccc([C@H](C)Oc2ccccc2)cc1>>C[C@H](Oc1ccccc1)c1ccc(C(=O)O)cc1 -US20100204246A1,1,C[C@H](Nc1nc(F)c(F)cc1[N+](=O)[O-])c1ccc(F)cn1.Cc1cc(N)n[nH]1>>Cc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)c([N+](=O)[O-])cc2F)n[nH]1 -US20090069288A1,6,CC(C)Oc1ccc(-c2cc(C(=O)Nc3ccc([C@@H](C)NC(=O)OC(C)(C)C)cc3)no2)cc1Cl>>CC(C)Oc1ccc(-c2cc(C(=O)Nc3ccc([C@@H](C)N)cc3)no2)cc1Cl -US20070010537A1,6,CC(C)(C)[Si](C)(C)OC1COc2ccccc2N(S(=O)(=O)c2cccc([N+](=O)[O-])c2)C1>>O=[N+]([O-])c1cccc(S(=O)(=O)N2CC(O)COc3ccccc32)c1 -US08163755B2,3,CNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cn1ccc(CN2C(=O)C3(C)COCCN3c3nc(Cl)ncc32)n1>>CNC(=O)Nc1ccc(-c2ncc3c(n2)N2CCOCC2(C)C(=O)N3Cc2ccn(C)n2)cc1 -US20070021606A1,1,CON(C)C(=O)CCl.O=S(=O)(c1cc(CO)c(Cl)cc1Cl)N1CCCCC1>>CON(C)C(=O)COCc1cc(S(=O)(=O)N2CCCCC2)c(Cl)cc1Cl -US04780528,6,COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H]1CCCN1C(=O)OCc1ccccc1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H]1CCCN1 -US20090318690A1,1,CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCNCC3)noc12.O=Cc1ccc(Cl)cc1>>CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCN(Cc4ccc(Cl)cc4)CC3)noc12 -US20100056502A1,6,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)[C@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O>>CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)[C@H]1CCNC[C@H]1O -US20140142074A1,2,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C.CS(=O)(=O)Cl>>COC(=O)[C@H](Cc1ccc(OS(C)(=O)=O)cc1)NC(=O)OC(C)(C)C -US20150087626A1,6,COC(=O)C1(C)CC2(CCN1C(=O)OC(C)(C)C)CC2>>CC(C)(C)OC(=O)N1CCC2(CC2)CC1(C)C(=O)O -US20150072973A1,6,COC(=O)c1ccc2c(C)c3c(nc2c1)CCCC3>>Cc1c2c(nc3cc(C(=O)O)ccc13)CCCC2 -US08273745B2,1,CCOC(=O)CBr.OCCCc1cccc(O)c1>>CCOC(=O)COc1cccc(CCCO)c1 -US08268822B2,3,CC(C)Cc1ccc(B(O)O)cc1.Clc1ccnc(Cl)n1>>CC(C)Cc1ccc(-c2ccnc(Cl)n2)cc1 -US20120165310A1,1,C1CNC1.Nc1ncnc2c1c(-c1cccc(OCC34CCC(CC3)O4)c1)cn2C1CC(C=O)C1>>Nc1ncnc2c1c(-c1cccc(OCC34CCC(CC3)O4)c1)cn2C1CC(CN2CCC2)C1 -US20150266872A1,6,CCOC(=O)c1cnc2c(-c3cnco3)cc(C3CC3)cn12>>O=C(O)c1cnc2c(-c3cnco3)cc(C3CC3)cn12 -US04276289,2,CO[C@@H]1[C@H](NC(=O)C(F)(F)F)C[C@H](O)O[C@H]1C.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CO[C@@H]1[C@H](NC(=O)C(F)(F)F)CC(OC(=O)c2ccc([N+](=O)[O-])cc2)O[C@H]1C -US20100144702A1,2,C1COCCN1.CN(c1cccc2cc(C3=NCC(C(=O)O)S3)[nH]c12)S(=O)(=O)c1cccs1>>CN(c1cccc2cc(C3=NCC(C(=O)N4CCOCC4)S3)[nH]c12)S(=O)(=O)c1cccs1 -US20080207642A1,6,COC(=O)c1c(Cn2c(C)nc(Cl)c2Cl)sc2c1c(=O)n(C)c(=O)n2CC(C)C>>Cc1nc(Cl)c(Cl)n1Cc1sc2c(c1C(=O)O)c(=O)n(C)c(=O)n2CC(C)C -US20110086834A1,1,COCCO.O=[N+]([O-])c1cc(I)ccc1F>>COCCOc1ccc(I)cc1[N+](=O)[O-] -US04803218,5,NCCc1c[nH]c2ccc([N+](=O)[O-])cc12.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCc1c[nH]c2ccc([N+](=O)[O-])cc12)C(F)(F)F -US20090054407A1,1,CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(C=O)ccc21.Nc1ccc(CCO)cc1>>CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(CNc3ccc(CCO)cc3)ccc21 -US09067898B1,1,CCOC(=O)CCc1ccc(O)c(C)c1C.CCc1ccc(-c2snc(Cl)c2COS(C)(=O)=O)cc1>>CCOC(=O)CCc1ccc(OCc2c(Cl)nsc2-c2ccc(CC)cc2)c(C)c1C -US20140213586A1,1,COc1cccc(N)c1.Cc1ccc2nc(C=O)cn2c1>>COc1cccc(N=Cc2cn3cc(C)ccc3n2)c1 -US05352705,2,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.NCCc1ccccc1>>CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)NCCc1ccccc1 -US20150133425A1,2,COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)O)C3.N#CC1CNC1>>COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)N1CC(C#N)C1)C3 -US04988814,2,CC(C)(C)N.O=C(O)CCBr>>CC(C)(C)NC(=O)CCBr -US20100010053A1,6,CCOC(=O)CCc1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cc(F)cc12>>CC(C)Oc1ccc(-c2nc(-c3cc(F)cc4c(CCC(=O)O)c[nH]c34)no2)cc1Cl -US04950674,1,Cc1cccc(OCCCCl)c1.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>Cc1cccc(OCCCN2CCC(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c1 -US20090192096A1,6,O=C(O)c1ccccc1-c1ccccc1CN1C(=O)c2ccccc2C1=O>>NCc1ccccc1-c1ccccc1C(=O)O -US20040024034A1,7,C=CCc1ccccc1OCC(=O)OCC>>CCCc1ccccc1OCC(=O)OCC -US20090054431A1,9,N.O=[N+]([O-])c1c(F)cc(F)cc1F>>Nc1cc(F)cc(F)c1[N+](=O)[O-] -US07378439B2,9,O=C1Nc2cccc(CCN3C(=O)c4ccccc4C3=O)c2C1Cl>>O=C1Cc2c(CCN3C(=O)c4ccccc4C3=O)cccc2N1 -US07229987B2,1,CN1CCCC1CCCl.Oc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1>>CN1CCCC1CCOc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1 -US20090221555A1,1,OCC1CCOC1.Oc1cccc(F)c1Nc1nc(Cl)ncc1Cl>>Fc1cccc(OCC2CCOC2)c1Nc1nc(Cl)ncc1Cl -US20140155385A1,2,COC/C=C/C(=O)O.Nc1nccn2c([C@@H]3CCCN3)nc(-c3ccc(C(=O)Nc4ccccn4)cc3)c12>>COC/C=C/C(=O)N1CCC[C@H]1c1nc(-c2ccc(C(=O)Nc3ccccn3)cc2)c2c(N)nccn12 -US07863332B2,6,CCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCCCC)c1>>CCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)O)cc2OCCCC)c1 -US07763584B2,2,CO[C@@]1(c2ccc(-c3ccccc3)cc2)C[C@H]2C(=O)N[C@]3(C(=O)O)C[C@H]3C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N2C1.NS(=O)(=O)C1CC1>>CO[C@@]1(c2ccc(-c3ccccc3)cc2)C[C@H]2C(=O)N[C@]3(C(=O)NS(=O)(=O)C4CC4)C[C@H]3C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N2C1 -US20090270412A1,3,C=O.CNCCc1cn(CCC2CCCCC2)c2ccc(C)cc12>>Cc1ccc2c(c1)c1c(n2CCC2CCCCC2)CN(C)CC1 -US04816582,6,CCOC(=O)/C(=N\OCC(=O)N1CCCCCC1)c1csc(N)n1>>Nc1nc(/C(=N/OCC(=O)N2CCCCCC2)C(=O)O)cs1 -US20140155445A1,1,BrCCc1ccccc1.c1c[nH]cn1>>c1ccc(CCn2ccnc2)cc1 -US08618301B2,3,C[Mg+].O=Cc1cccc(-c2ccn3nc(-c4ccc(Cl)cc4)cc3c2)c1>>CC(O)c1cccc(-c2ccn3nc(-c4ccc(Cl)cc4)cc3c2)c1 -US08501750B2,1,CCc1cc2c(=O)[nH]c(=O)n(Cc3ccc(-c4ccc(F)cc4C#N)cc3)c2s1.COc1ccc(C(=O)CBr)cc1>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccc(F)cc4C#N)cc3)c2s1 -US08946260B2,1,Cc1ccncc1N1CCc2ccc(O)cc2C1=O.Fc1cnc(Cl)nc1>>Cc1ccncc1N1CCc2ccc(Oc3ncc(F)cn3)cc2C1=O -US20080051405A1,1,C=O.COc1ccc(-c2cc3cnn(Cc4cccc(OC[C@@H]5CCCCN5)n4)c(=O)c3s2)cc1>>COc1ccc(-c2cc3cnn(Cc4cccc(OC[C@@H]5CCCCN5C)n4)c(=O)c3s2)cc1 -US07947728B1,6,CCOC(=O)CCn1ncc2c(COc3ccc(-c4cc(F)c(F)cc4OC)cc3)cccc21>>COc1cc(F)c(F)cc1-c1ccc(OCc2cccc3c2cnn3CCC(=O)O)cc1 -US20080255152A1,6,CCOC(=O)c1ccc(Oc2ccc(C=O)cc2)nc1>>O=Cc1ccc(Oc2ccc(C(=O)O)cn2)cc1 -US05093353,1,BrCCCOc1cccc2c1CCCC2.CCCc1c(O)c(C(C)=O)cc2c1OC(CCC(=O)OCC)(CCC(=O)OCC)CC2>>CCCc1c2c(cc(C(C)=O)c1OCCCOc1cccc3c1CCCC3)CCC(CCC(=O)OCC)(CCC(=O)OCC)O2 -US07572809B2,1,COc1ccc2cc(Nc3cc(C)[nH]n3)nc(Cl)c2c1.Oc1ccc(Cl)cc1>>COc1ccc2cc(Nc3cc(C)[nH]n3)nc(Oc3ccc(Cl)cc3)c2c1 -US20100137362A1,6,COC(=O)c1cc(Cl)nc(C)c1N>>Cc1nc(Cl)cc(C(=O)O)c1N -US20040121965A1,2,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](N)[C@H](C)OC.CN(C(=O)OC(C)(C)C)[C@H](C(=O)O)C(C)(C)c1ccccc1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1)[C@H](C)OC -US08629270B2,9,C=CCN(CC=C)CC(=O)c1ccc(F)cc1.NO>>C=CCN(CC=C)CC(=NO)c1ccc(F)cc1 -US04882439,3,CC(=O)Cl.CC(C)(C)C(=O)O[C@@H]1C[C@]2(C)[C@@H](OC(=O)C(C)(C)C)CC[C@H]2[C@@H]2CCc3ccccc3[C@@H]12>>CC(=O)c1ccc2c(c1)[C@H]1[C@H](OC(=O)C(C)(C)C)C[C@]3(C)[C@@H](OC(=O)C(C)(C)C)CC[C@H]3[C@@H]1CC2 -US05521179,2,CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(N)c1=O)(O[SiH](C)C)C(C(C)(C)C)C(F)(F)F.O=C(Cl)Cc1ccccc1>>CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)Cc2ccccc2)c1=O)(O[SiH](C)C)C(C(C)(C)C)C(F)(F)F -US20080287430A1,1,CCOC(=O)c1ccc(Cc2cc(Cl)ccc2O)o1.Fc1ccc(CBr)c(F)c1>>CCOC(=O)c1ccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2F)o1 -US07538231B2,3,CCc1c(C(=O)OC(C)(C)C)[nH]c(C=O)c1I.OB(O)c1cc2ccccc2o1>>CCc1c(C(=O)OC(C)(C)C)[nH]c(C=O)c1-c1cc2ccccc2o1 -US20070004679A1,1,N#Cc1ccc(F)c2ccccc12.OC1(Cc2ccccc2)CCNCC1>>N#Cc1ccc(N2CCC(O)(Cc3ccccc3)CC2)c2ccccc12 -US06008245,1,CCCI.CN(C1=CC(C)(C)Oc2ccc(O)cc21)S(C)(=O)=O>>CCCOc1ccc2c(c1)C(N(C)S(C)(=O)=O)=CC(C)(C)O2 -US06897231B2,4,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].N#Cc1ccc2[nH]nc(-c3ccc4ccccc4c3)c2c1>>c1ccc2cc(-c3n[nH]c4ccc(-c5nnn[nH]5)cc34)ccc2c1 -US05387592,10,COC(=O)c1ccccc1-c1nc2cc(C)ccc2o1.O=C1CCC(=O)N1Br>>COC(=O)c1ccccc1-c1nc2cc(CBr)ccc2o1 -US20050096380A1,8,CCOc1c(/C(C)=C(/F)CO)cc2c(c1Br)C(C)(C)CC=C2C(C)(C)C>>CCOc1c(/C(C)=C(/F)C=O)cc2c(c1Br)C(C)(C)CC=C2C(C)(C)C -US05541324,1,O=C(O)c1ncn2c1CN(C(=O)N1CCCC1)c1ccccc1-2.Oc1ccccc1>>O=C(Oc1ccccc1)c1ncn2c1CN(C(=O)N1CCCC1)c1ccccc1-2 -US20100034827A1,6,CC(=O)Nc1cc(COC(C)=O)ccn1>>CC(=O)Nc1cc(CO)ccn1 -US04203986,1,Fc1ccc(N2CCNCC2)cc1C(F)(F)F.OCCBr>>OCCN1CCN(c2ccc(F)c(C(F)(F)F)c2)CC1 -US20100249123A1,2,COc1ccc(C(=O)Cl)cc1OC.N#CC1(c2cccc(N)c2)CCCC1>>COc1ccc(C(=O)Nc2cccc(C3(C#N)CCCC3)c2)cc1OC -US20130045963A1,1,C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CNC4)c3)ncnc21.O=C1CCC(Oc2cc(C(=O)O)nc(C(F)(F)F)n2)CC1>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CN([C@@H]5CC[C@H](Oc6cc(C(=O)O)nc(C(F)(F)F)n6)CC5)C4)c3)ncnc21 -US07199239B2,1,CCOC(=O)COc1ccc(CBr)cc1C.COCCNc1cccc(-c2ccc(C(F)(F)F)cc2)c1C>>CCOC(=O)COc1ccc(CN(CCOC)c2cccc(-c3ccc(C(F)(F)F)cc3)c2C)cc1C -US20120329830A1,1,COc1ccc(CN)cc1.O=Cc1cc2cc(Br)ccc2nc1Cl>>COc1ccc(CNc2nc3ccc(Br)cc3cc2C=O)cc1 -US20110118245A1,6,COc1cc2c(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)ncnc2cc1O[C@H]1CCN(C(=O)OC(C)(C)C)C1>>COc1cc2c(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)ncnc2cc1O[C@H]1CCNC1 -US20070249670A1,2,CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1N)C(=O)OCc1ccccc1.Cc1cc(Br)cc(C)c1N=C=O>>CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(Br)cc1C)C(=O)OCc1ccccc1 -US20040220191A1,6,COC(=O)c1ccc(N2CCC(C)CC2)c(F)c1>>CC1CCN(c2ccc(C(=O)O)cc2F)CC1 -US05521179,6,CC(C)(C)OC(=O)Cn1c(CCc2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O>>O=C(O)Cn1c(CCc2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O -US06420375B1,7,COC(=O)/C=C(\C)c1ccc2ccccc2c1>>C/C(=C\CO)c1ccc2ccccc2c1 -US07618978B2,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.COC(=O)c1cc(Cl)nc(Cl)c1>>C=C(OCC)c1cc(C(=O)OC)cc(Cl)n1 -US05620979,7,Nc1c(Cl)cc(F)cc1[N+](=O)[O-]>>Nc1cc(F)cc(Cl)c1N -US20130116203A1,9,COc1cc(OC)c(CN)c(OC)c1.S=C(Cl)Cl>>COc1cc(OC)c(CN=C=S)c(OC)c1 -US04695312,1,FC(F)Cl.O=[N+]([O-])c1cc(O)c(Cl)cc1F>>O=[N+]([O-])c1cc(OC(F)F)c(Cl)cc1F -US06255305B1,7,C[Si](C)(C)CCOCn1ccnc1C=O>>C[Si](C)(C)CCOCn1ccnc1CO -US20050090485A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc2c(c1)CCNCC2>>CC(C)(C)OC(=O)N1CCc2ccc([N+](=O)[O-])cc2CC1 -US07625901B2,2,CCC(Cl)C(=O)Cl.N[C@@H](CO)c1cc(F)cc(F)c1>>CCC(Cl)C(=O)N[C@@H](CO)c1cc(F)cc(F)c1 -US20130336918A1,2,CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)O)c1.Nc1ccc(N2CCCCC2)cc1C(=O)Nc1cnc(-c2ccccc2)nc1>>CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2cnc(-c3ccccc3)nc2)c1 -US20150057263A1,1,CNC1CCN(Cc2ccccc2)CC1.COc1cc2nc(Cl)nc(Cl)c2cc1OC>>COc1cc2nc(Cl)nc(N(C)C3CCN(Cc4ccccc4)CC3)c2cc1OC -US20120115841A1,1,C1CCNC1.NCCOCCO>>NCCOCCN1CCCC1 -US06410592B1,3,C=O.NCCc1ccccc1.O=C1CCCc2c1ccc1ccccc21>>O=C1c2ccc3ccccc3c2CCC1CNCCc1ccccc1 -US07064124B2,7,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3cc(OC)c(OC)c(OC)c3)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)Nc3cc(OC)c(OC)c(OC)c3)c2)=C(C)C1=O -US04404230,6,COc1cccc2c1C(N)=NS2(=O)=O>>NC1=NS(=O)(=O)c2cccc(O)c21 -US04564609,6,O=C(N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)NC1CCCCC1)OCc1ccccc1>>N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)NC1CCCCC1 -US20090182029A1,2,Nc1ccc(F)cc1N.O=C(O)CCCCCCCNC(=O)c1ccc(C=NN=C2C(=O)Nc3ccc(F)cc32)cc1>>Nc1cc(F)ccc1NC(=O)CCCCCCCNC(=O)c1ccc(C=NN=C2C(=O)Nc3ccc(F)cc32)cc1 -US07141598B2,2,NC1CC1.O=C(O)c1ccc2cc(Br)ccc2c1>>O=C(NC1CC1)c1ccc2cc(Br)ccc2c1 -US04423047,8,C=CCSc1ncc(Cl)cn1.OO>>C=CCS(=O)c1ncc(Cl)cn1 -US20080004271A1,1,N#Cc1c(Cl)ncnc1-c1cccc(NC(=O)Nc2ccc(C(F)(F)F)cc2)c1.NC(=O)CS>>N#Cc1c(SCC(N)=O)ncnc1-c1cccc(NC(=O)Nc2ccc(C(F)(F)F)cc2)c1 -US20110118236A1,2,CC(C)(C)OC(=O)N1CCc2c(c(C(F)(F)F)nn2CC(=O)O)C1.CC(N)c1ccc(Cl)cc1>>CC(NC(=O)Cn1nc(C(F)(F)F)c2c1CCN(C(=O)OC(C)(C)C)C2)c1ccc(Cl)cc1 -US08188114B2,1,BrCc1ccccc1.Cc1[nH]c2c(N3CCc4ccccc4C3)nccc2c1C>>Cc1c(C)n(Cc2ccccc2)c2c(N3CCc4ccccc4C3)nccc12 -US04259333,9,[N-]=[N+]=NCCCC1CCN(C=O)CC1>>NCCCC1CCN(C=O)CC1 -US04542142,2,C#CC(O)c1cccc(Oc2ccccc2)c1.CC1(C)[C@@H](/C=C\C(=O)OCC(F)F)[C@H]1C(=O)O>>C#C[C@@H](OC(=O)[C@@H]1[C@H](/C=C\C(=O)OCC(F)F)C1(C)C)c1cccc(Oc2ccccc2)c1 -US20030055064A1,6,CC(=O)N1CCN(c2nc(N(C)C)cc(N(C)C)n2)CC1>>CN(C)c1cc(N(C)C)nc(N2CCNCC2)n1 -US08552047B2,6,CCOC(=O)[C@@H](NC(=O)OC)C1C[C@@H](C)O[C@H](C)C1>>COC(=O)N[C@H](C(=O)O)C1C[C@@H](C)O[C@H](C)C1 -US20150274663A1,3,CCCCCCCCOc1cccc(Br)c1.OB(O)c1cccnc1>>CCCCCCCCOc1cccc(-c2cccnc2)c1 -US20090325936A1,9,O=C(NCc1ccc(Br)cc1F)c1nc(-c2ccc(F)cc2)n2ccccc12.[C-]#N>>N#Cc1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n3ccccc23)c(F)c1 -US20100137276A1,1,FC(F)(F)c1n[nH]c2c1COCC2.O=S(=O)(NCC1CCCO1)c1ccc(I)cc1>>O=S(=O)(NCC1CCCO1)c1ccc(-n2nc(C(F)(F)F)c3c2CCOC3)cc1 -US20080188484A1,6,CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCN(S(=O)(=O)C5CC5)CC4)n(CCO[Si](C)(C)C(C)(C)C)c3cc2Br)CC1>>CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCN(S(=O)(=O)C5CC5)CC4)n(CCO)c3cc2Br)CC1 -US20110082111A1,1,CI.C[C@@H]1CCC(N2CC(F)(F)C(=O)Nc3cnc(Cl)nc32)C1>>C[C@@H]1CCC(N2CC(F)(F)C(=O)N(C)c3cnc(Cl)nc32)C1 -US07304062B2,1,CC(C)(C)OC(=O)NN.COc1cccc(C=O)c1>>COc1cccc(C=NNC(=O)OC(C)(C)C)c1 -US08404709B2,6,COc1cc(C#N)ccc1C=O>>N#Cc1ccc(C=O)c(O)c1 -US20020143182A1,3,COc1ccc(-c2ccc(C=O)cc2)cc1C12CC3CC(CC(C3)C1)C2.O=C1CSC(=O)N1>>COc1ccc(-c2ccc(C=C3SC(=O)NC3=O)cc2)cc1C12CC3CC(CC(C3)C1)C2 -US06432950B1,1,Cc1sc2nc(Cl)nc(NCc3ccccc3)c2c1C.c1cn[nH]c1>>Cc1sc2nc(-n3cccn3)nc(NCc3ccccc3)c2c1C -US20110112151A1,1,O=C(CBr)C1(c2ccc(Cl)cc2)CCCCC1.Sc1ccccn1>>O=C(CSc1ccccn1)C1(c2ccc(Cl)cc2)CCCCC1 -US20120232072A1,3,COc1ncc(B(O)O)c(OC)n1.O=Cc1cnc2ccc(Br)cn12>>COc1ncc(-c2ccc3ncc(C=O)n3c2)c(OC)n1 -US07723367B2,1,N#Cc1cccnc1F.Oc1cncc(Cl)c1>>N#Cc1cccnc1Oc1cncc(Cl)c1 -US07932390B2,9,CCOC(=O)c1cnc(Cl)c2c(COc3cccc(-c4nnn(C)n4)c3)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3cccc(-c4nnn(C)n4)c3)csc12 -US20110257100A1,1,CC(C)(C)OC(=O)N1CCNC(=O)C1.O=C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CCl)cn4)sc23)c(F)c1)NC1CC1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)C(=O)C1 -US07074794B2,2,COC(=O)[C@@H]1C[C@H](N)CN1C(=O)OC(C)(C)C.O=C(Cl)c1ccccc1>>COC(=O)[C@@H]1C[C@H](NC(=O)c2ccccc2)CN1C(=O)OC(C)(C)C -US04973592,2,Cc1ncc(O)cn1.O=C(Cl)C1(C2CCCCC2)CCCCC1>>Cc1ncc(OC(=O)C2(C3CCCCC3)CCCCC2)cn1 -US08273767B2,3,C[C@@H]1CCCN1CCc1cc2ccc(Br)cc2cn1.N#Cc1ccc(B(O)O)cc1>>C[C@@H]1CCCN1CCc1cc2ccc(-c3ccc(C#N)cc3)cc2cn1 -US20060160811A1,6,CC1CCN(c2c(-c3c(F)cc(F)cc3F)c(OCc3ccccc3)nc3ncncc23)CC1>>CC1CCN(c2c(-c3c(F)cc(F)cc3F)c(O)nc3ncncc23)CC1 -US20150152093A1,1,C[C@H](F)[C@H]1COC(=O)N1c1nc(F)ncc1F.Cc1cc([C@H](C)N)ncc1-c1ccnc(C(F)(F)F)c1>>Cc1cc([C@H](C)Nc2ncc(F)c(N3C(=O)OC[C@@H]3[C@H](C)F)n2)ncc1-c1ccnc(C(F)(F)F)c1 -US20070293521A1,1,CCOC(=O)C1CCN(C(=O)c2cccc(N)c2)CC1.Oc1cccc(Nc2nc(Cl)ncc2F)c1>>CCOC(=O)C1CCN(C(=O)c2cccc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)c2)CC1 -US20100280268A1,6,COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(OCc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc(Oc3ccc(NS(=O)(=O)c4ccc(C)cc4)c(C(=O)O)c3)cc2OCc2ccccc2)cc1 -US07393868B2,5,Brc1ccc(-c2ccn[nH]2)cc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1nccc1-c1ccc(Br)cc1 -US20020193614A1,9,BrC(Br)(Br)Br.CSc1ccc(CO)cc1>>CSc1ccc(CBr)cc1 -US20060094725A1,1,ClCc1ccc2c(c1)OCO2.c1cn(-c2ccc(OC3CCCNC3)nn2)cn1>>c1cn(-c2ccc(OC3CCCN(Cc4ccc5c(c4)OCO5)C3)nn2)cn1 -US08372307B2,7,CCCC1CCC(C2CCC(CCC(=O)OCC)CC2)CC1>>CCCC1CCC(C2CCC(CCCO)CC2)CC1 -US20100093757A1,2,COC(=O)[C@H](COCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)Oc1ncnc2c1cnn2-c1cc(F)ccc1C.Nc1ccc(Cl)cn1>>Cc1ccc(F)cc1-n1ncc2c(O[C@@H](COCCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C(=O)Nc3ccc(Cl)cn3)ncnc21 -US20140171409A1,6,CC(C)(C)OC(=O)N1CC(CC#N)(n2cc(-c3ccnc4c3ccn4COCC[Si](C)(C)C)cn2)C1>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CNC4)c3)ccnc21 -US04985444,7,O=C(O)/C=C/C(=O)c1c(-c2ccccc2)nn2ccccc12>>O=C(O)CCC(=O)c1c(-c2ccccc2)nn2ccccc12 -US04772600,6,CCOC(=O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21 -US20150158864A1,1,CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12.C[C@H]1C[C@@H](N)CCN1C(=O)OC(C)(C)C>>C[C@H]1C[C@@H](Nc2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)CCN1C(=O)OC(C)(C)C -US08138187B2,7,Cc1c(C2=CCC(Cc3ccccc3)(N(C)C)CC2)[nH]c2ccc(OC(F)(F)F)cc12>>Cc1c(C2CCC(Cc3ccccc3)(N(C)C)CC2)[nH]c2ccc(OC(F)(F)F)cc12 -US20100292188A1,2,COC(=O)CC(=O)Cl.c1cc(-c2nc3c(s2)CNCC3)ccc1O[C@@H]1C[C@@H](N2CCCCC2)C1>>COC(=O)CC(=O)N1CCc2nc(-c3ccc(O[C@@H]4C[C@@H](N5CCCCC5)C4)cc3)sc2C1 -US20090264405A1,1,O=C(O)CBr.OC1CCC1>>O=C(O)COC1CCC1 -US05530138,1,ClCC12CCCN1CCC2.O=CNc1cccc2ccccc12>>O=CN(CC12CCCN1CCC2)c1cccc2ccccc12 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.Oc1ccc(F)cc1Cl>>CC#CCOc1cc(Oc2ccc(F)cc2Cl)ncn1 -US08178699B2,2,COC(=O)c1sccc1N.O=S(=O)(Cl)c1ccc2c(c1)CCC2>>COC(=O)c1sccc1NS(=O)(=O)c1ccc2c(c1)CCC2 -US20060142347A1,1,COC(=O)c1sc(-c2ccccc2)cc1Br.NC1CC1>>COC(=O)c1sc(-c2ccccc2)cc1NC1CC1 -US20050124664A1,2,CC(=O)c1ccc[nH]1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC(=O)c1cccn1C(=O)c1ccc([N+](=O)[O-])cc1 -US05756817,6,CC(C)(C)OC(=O)N[C@H](COC(N)=O)Cc1ccccc1F>>NC(=O)OC[C@@H](N)Cc1ccccc1F -US20060166992A1,8,COc1cc(Oc2nc(-c3cccnc3)nn3c(C(C)C)nc(C)c23)cc(OC)c1OC.O=C(OO)c1cccc(Cl)c1>>COc1cc(Oc2nc(-c3ccc[n+]([O-])c3)nn3c(C(C)C)nc(C)c23)cc(OC)c1OC -US20150210703A1,1,CC[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1N.NC(=O)c1cnn2cc(Br)nc2c1Cl>>CC[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1Nc1c(C(N)=O)cnn2cc(Br)nc12 -US08569535B2,6,C=CCOc1c(Cl)cccc1C(=O)NC1(C(=O)OCC)Cc2ccccc2C1>>C=CCOc1c(Cl)cccc1C(=O)NC1(C(=O)O)Cc2ccccc2C1 -US20090312381A1,2,C=CCN=C=O.NNC(=O)c1ccc(Cl)cc1>>C=CCNC(=O)NNC(=O)c1ccc(Cl)cc1 -US04658061,1,CC(=O)CCC1(C(N)=O)c2ccccc2-c2ccccc21.CC(C)N>>CC(C)NC(C)CCC1(C(N)=O)c2ccccc2-c2ccccc21 -US09132126B2,2,FC(F)(F)c1cccc(N2CCNCC2)c1.Nc1onc(-c2ccc(OC(F)(F)F)cc2)c1C(=O)O>>Nc1onc(-c2ccc(OC(F)(F)F)cc2)c1C(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1 -US20150126537A1,2,CCOP(=O)(CC(=O)O)OCC.COc1cc2ncnc(Nc3ccc(Oc4ccc(F)cc4)cc3)c2cc1N>>CCOP(=O)(CC(=O)Nc1cc2c(Nc3ccc(Oc4ccc(F)cc4)cc3)ncnc2cc1OC)OCC -US04195023,1,O=C(Cl)c1ccccc1F.O=C1NS(=O)(=O)c2ccccc21>>O=C(c1ccccc1F)N1C(=O)c2ccccc2S1(=O)=O -US05721254,1,CI.O=C1Nc2ccccc2Nc2ccccc21>>CN1C(=O)c2ccccc2Nc2ccccc21 -US05470862,4,C#CC=O.CCOC(=O)C=[N+]=[N-]>>CCOC(=O)c1cc(C=O)[nH]n1 -US04789680,4,COC(=O)C#CC(=O)OC.[N-]=[N+]=NCc1ccccc1F>>COC(=O)c1nnn(Cc2ccccc2F)c1C(=O)OC -US08188139B2,1,C1COCCN1.CC(C)(C)OC(=O)N1Cc2cc(I)c(C(F)(F)F)cc2C1>>CC(C)(C)OC(=O)N1Cc2cc(N3CCOCC3)c(C(F)(F)F)cc2C1 -US20070155727A1,2,COC(=O)c1ccc(C(=O)[O-])cc1.O=C(CN1CCNCC1)Nc1ccc(Oc2ccccc2)cc1>>COC(=O)c1ccc(C(=O)N2CCN(CC(=O)Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 -US06353015B1,2,CCCC(=O)OC(=O)CCC.NCCc1c[nH]c2ccc(OCc3ccccc3)cc12>>CCCC(=O)NCCc1c[nH]c2ccc(OCc3ccccc3)cc12 -US20070155746A1,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Nc1cccc(Oc2ccnc(Cl)c2)c1>>Cn1cc(-c2cc(Oc3cccc(N)c3)ccn2)cn1 -US06414008B1,1,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CN)n2C)c1ccccn1.N#Cc1ccc(Cl)nc1>>CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C#N)cn1)n2C)c1ccccn1 -US08435980B2,1,COc1cnc2[nH]cc(-c3cc(Cl)nc(Cl)c3)c2c1.N[C@H]1CC[C@H](O)CC1>>COc1cnc2[nH]cc(-c3cc(Cl)nc(N[C@@H]4CC[C@@H](O)CC4)c3)c2c1 -US20100298306A1,2,C1CN2CCC(CC2)N1.O=C(O)c1cc(C2CC2)[nH]n1>>O=C(c1cc(C2CC2)[nH]n1)N1CCN2CCC1CC2 -US20080139533A1,1,C[Si](C)(C)CCOCn1cnc(C=O)c1F.c1ccc2c(c1)CCCN2>>C[Si](C)(C)CCOCn1cnc(CN2CCCc3ccccc32)c1F -US05783575,2,CC(=O)Cl.COC(=O)c1cc2c([nH]c3ccccc32)s1>>COC(=O)c1cc2c3ccccc3n(C(C)=O)c2s1 -US06599940B2,6,COC(=O)[C@@]12CO[C@@H](C(C)(C)C)N1C(=O)[C@](Cc1ccccc1)(C(=O)OCc1ccccc1)C2>>COC(=O)[C@@]12CO[C@@H](C(C)(C)C)N1C(=O)[C@](Cc1ccccc1)(C(=O)O)C2 -US05001157,2,NC(=O)c1ccccc1N.O=C(N=C=S)c1ccc(Cl)cc1>>NC(=O)c1ccccc1NC(=S)NC(=O)c1ccc(Cl)cc1 -US05648373,9,BrCCCCCCn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1.[C-]#N>>N#CCCCCCCn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1 -US06365753B1,2,CC(C)O.O=C(Cl)C(Cl)Cc1cc(N2C(=O)c3ccccc3C2=O)c(F)cc1Cl>>CC(C)OC(=O)C(Cl)Cc1cc(N2C(=O)c3ccccc3C2=O)c(F)cc1Cl -US04009187,3,CN(C)C=O.COC(=O)CCCCCCCc1ccco1>>COC(=O)CCCCCCCc1ccc(C=O)o1 -US20060079698A1,2,CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)Cl.O=C(O)[C@@H]1C[C@H]2CCCC[C@@H]2N1>>CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@H]2CCCC[C@@H]21 -US20140093907A1,3,C=Cc1ccc(N(CCCC)CCCC)cc1.O=Cc1ccc(Br)cc1>>CCCCN(CCCC)c1ccc(/C=C/c2ccc(C=O)cc2)cc1 -US06992103B2,1,C[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccc(F)c(Br)c1)C(=O)NCCC(C)(C)C.O=C1CCCN1>>C[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccc(F)c(N2CCCC2=O)c1)C(=O)NCCC(C)(C)C -US08426437B2,3,C#Cc1ccc2[nH]c(=O)c3[nH]ccc3c2c1.C1COCCN1.C=O>>O=c1[nH]c2ccc(C#CCN3CCOCC3)cc2c2cc[nH]c12 -US20140336177A1,6,COc1cc([C@H]2CN3CCN(C(=O)OC(C)(C)C)C[C@@H]3CO2)ccc1C#N>>COc1cc([C@H]2CN3CCNC[C@@H]3CO2)ccc1C#N -US20140296256A1,2,COC(=O)c1cc(Br)ccc1N.O=C(O)COc1cccc(-c2ccoc2)c1>>COC(=O)c1cc(Br)ccc1NC(=O)COc1cccc(-c2ccoc2)c1 -US05055464,9,COC(=O)C1(N)C(=O)Nc2ccccc2CC1c1ccccc1>>N[C@@H]1C(=O)Nc2ccccc2C[C@@H]1c1ccccc1 -US05055464,9,COC(=O)C1(N)C(=O)Nc2ccccc2CC1c1ccccc1>>N[C@@H]1C(=O)Nc2ccccc2C[C@H]1c1ccccc1 -US06531502B1,3,COc1ccc(C=O)cc1C(C)C.O=C1Cc2cc(Cl)ccc2N1>>COc1ccc(C=C2C(=O)Nc3ccc(Cl)cc32)cc1C(C)C -US08071588B2,3,NCc1ccc(F)c(Br)c1.OCc1cccc(B(O)O)c1>>NCc1ccc(F)c(-c2cccc(CO)c2)c1 -US20100227880A1,1,CN(C)c1cc(-c2c(C=O)nc3ccccn23)ccn1.CN[C@H]1CCCc2cccnc21>>CN(C)c1cc(-c2c(CN(C)[C@H]3CCCc4cccnc43)nc3ccccn23)ccn1 -US05310723,1,C=CCBr.Cn1c(C(F)(F)F)cc(=O)n(-c2cc3[nH]c(=O)ccc3cc2F)c1=O>>C=CCn1c(=O)ccc2cc(F)c(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc21 -US20100197744A1,1,COC(=O)CBr.COc1ccc2cc(OCc3ccccc3)c(N)cc2c1>>COC(=O)CNc1cc2cc(OC)ccc2cc1OCc1ccccc1 -US09045475B2,1,COCCN.NS(=O)(=O)c1ccc(F)c(S(=O)(=O)C(F)(F)F)c1>>COCCNc1ccc(S(N)(=O)=O)cc1S(=O)(=O)C(F)(F)F -US20150225449A1,6,COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@H](C)N(C(=O)CS(C)(=O)=O)c2ccccc21>>CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C -US20050277627A1,1,CC(C)(C)OC(=O)N1CCNCC1.COc1cc2c(c(OC)c1OC)-c1ccc(OC(=O)c3cccc(CCl)c3)cc1[C@@H](NC(C)=O)CC2>>COc1cc2c(c(OC)c1OC)-c1ccc(OC(=O)c3cccc(CN4CCN(C(=O)OC(C)(C)C)CC4)c3)cc1[C@@H](NC(C)=O)CC2 -US07034045B1,2,CC(C)S(=O)(=O)NCC(C)(F)c1ccc(NC(=O)c2ccc(C(=O)O)cn2)cc1.CN>>CNC(=O)c1ccc(C(=O)Nc2ccc(C(C)(F)CNS(=O)(=O)C(C)C)cc2)nc1 -US20060276433A1,7,O=[N+]([O-])c1ccc(C2=NCCO2)cc1>>Nc1ccc(C2=NCCO2)cc1 -US05547950,2,CC(=O)NC[C@H]1CN(c2ccc(N3CCNCC3)c(F)c2)C(=O)O1.O=C(O)CCN1CCOCC1>>CC(=O)NCC1CN(c2ccc(N3CCN(C(=O)CCN4CCOCC4)CC3)c(F)c2)C(=O)O1 -US06358971B1,6,O=C(c1ccccc1)c1ccc2nc(NC(=O)C(F)(F)F)c(-c3ccc(F)cc3F)n2c1>>Nc1nc2ccc(C(=O)c3ccccc3)cn2c1-c1ccc(F)cc1F -US04728646,1,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3c(SCc4cccc5ccccc45)ncnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3c(SCc4cccc5ccccc45)ncnc23)CC1 -US20130345181A1,3,COc1nc(Cl)ncc1N.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COc1nc(-c2cnn(C)c2)ncc1N -US07737166B2,7,CC(C)(C)c1nc2c(C(=O)O)cc(-c3ccccc3)c([N+](=O)[O-])c2o1>>CC(C)(C)c1nc2c(C(=O)O)cc(-c3ccccc3)c(N)c2o1 -US07741341B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(N2CCNCC2=O)cc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2)C(=O)C1 -US20090012078A1,1,Brc1ncc(Br)n2ncnc12.Nc1nc(CN2CCOCC2)cs1>>Brc1cnc(Nc2nc(CN3CCOCC3)cs2)c2ncnn12 -US20080167330A1,7,Cc1c(NC(=O)N=S(C)(C)=O)cccc1[N+](=O)[O-]>>Cc1c(N)cccc1NC(=O)N=S(C)(C)=O -US20040215018A1,7,c1ccc(-c2ccc3ccccc3n2)cc1>>c1ccc(C2CCc3ccccc3N2)cc1 -US20140163000A1,8,CN1CCc2c(cncc2NC(=O)c2c(N)nn3cc(F)cnc23)C1.O=C(OO)c1cccc(Cl)c1>>C[N+]1([O-])CCc2c(cncc2NC(=O)c2c(N)nn3cc(F)cnc23)C1 -US20070149577A1,3,COc1ncccc1B(O)O.C[C@H](c1ccc(Br)cc1)N1C(=O)c2ccccc2C1=O>>COc1ncccc1-c1ccc([C@@H](C)N2C(=O)c3ccccc3C2=O)cc1 -US07547700B2,7,CCOC(=O)c1ccc(COCOC)nc1>>COCOCc1ccc(CO)cn1 -US20070259851A1,3,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.COc1nc2ccn([Si](C(C)C)(C(C)C)C(C)C)c2cc1B(O)O>>COc1nc2ccn([Si](C(C)C)(C(C)C)C(C)C)c2cc1C1=CCN(C(=O)OC(C)(C)C)CC1 -US20100204207A1,6,COC(=O)c1cccc(CN2CCC[C@H](N(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3nnn(C)n3)c3cc(C)c(C(F)(F)F)cc32)c1>>Cc1cc2c(cc1C(F)(F)F)N(Cc1cccc(C(=O)O)c1)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](C2CC2)NC1=O.O=C(O)c1cc(-c2ccc(F)cc2)on1>>CC(C)C[C@H]1C(=O)N[C@@H](C2CC2)CN1C(=O)c1cc(-c2ccc(F)cc2)on1 -US07652022B2,1,CCN1CCNCC1.O=C(Nc1ccc(CBr)c(C(F)(F)F)c1)C(F)(F)F>>CCN1CCN(Cc2ccc(NC(=O)C(F)(F)F)cc2C(F)(F)F)CC1 -US20050250769A1,6,CC(=O)OC1C(NC(=O)c2cc(-c3cc(C(F)(F)F)ccc3C(F)(F)F)n(C[C@H]3CCCO3)c2C)C2CCC1(C)C2(C)C>>Cc1c(C(=O)NC2C3CCC(C)(C2O)C3(C)C)cc(-c2cc(C(F)(F)F)ccc2C(F)(F)F)n1C[C@H]1CCCO1 -US08153658B2,1,COC(=O)c1cc(F)c(F)c(F)c1.C[C@H](c1cccc2ccccc12)N(CC1CNCCC1c1ccccc1F)C(=O)OC(C)(C)C>>COC(=O)c1cc(F)c(N2CC[C@H](c3ccccc3F)[C@@H](CN(C(=O)OC(C)(C)C)[C@H](C)c3cccc4ccccc34)C2)c(F)c1 -US20110053923A1,3,CC(C)S(=O)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(Cl)n2)CC1.OB(O)c1cccc2[nH]ccc12>>CC(C)S(=O)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)n2)CC1 -US06465507B2,3,O=C1Cc2c(CCO)cccc2N1.O=Cc1[nH]cc2c1CCOC2=O>>O=C1Nc2cccc(CCO)c2C1=Cc1[nH]cc2c1CCOC2=O -US20090143367A1,3,COc1cc(F)c2nc(C)c3c(C)nc(Br)n3c2c1.Cc1ccccc1B(O)O>>COc1cc(F)c2nc(C)c3c(C)nc(-c4ccccc4C)n3c2c1 -US07776875B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(Oc2ccc(Cl)cc2/C=C2\C(=O)Nc3cc(Cl)ccc32)cc1>>COc1ccc(Oc2ccc(Cl)cc2/C=C2\C(=O)N(C(=O)OC(C)(C)C)c3cc(Cl)ccc32)cc1 -US08501780B2,1,CNC.NC(=O)c1cc(-c2cccs2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)n[nH]c12>>CN(C)CCCS(=O)(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(-c4cccs4)cc23)CC1 -US05807885,7,NCc1ccc([N+](=O)[O-])cc1>>NCc1ccc(N)cc1 -US05476851,1,CI.Clc1ccc(-c2cnc3cc4cn[nH]c4cc3n2)s1>>Cn1ncc2cc3ncc(-c4ccc(Cl)s4)nc3cc21 -US08637518B2,7,CC(=O)OCCn1cc(-c2ccc(=O)n(Cc3cccc(-c4ncc(OCCN5CCOCC5)cn4)c3)n2)cn1>>O=c1ccc(-c2cnn(CCO)c2)nn1Cc1cccc(-c2ncc(OCCN3CCOCC3)cn2)c1 -US07683056B2,6,CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N2C[C@H]3COCCN3C[C@H]2CO[Si](C)(C)C(C)(C)C)cc1-c1ccccc1CO>>CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N2C[C@H]3COCCN3C[C@H]2CO)cc1-c1ccccc1CO -US05399580,7,CC(=O)OC[C@@H]1C[C@H](Nc2cc(Cl)c(Cl)cc2[N+](=O)[O-])[C@@H](OC(C)=O)[C@H]1OC(C)=O>>CC(=O)OC[C@@H]1C[C@H](Nc2cc(Cl)c(Cl)cc2N)[C@@H](OC(C)=O)[C@H]1OC(C)=O -US07345067B2,1,CCOC(=O)CBr.Cc1cc(N)ccc1O>>CCOC(=O)COc1ccc(N)cc1C -US20120264735A1,4,CC(C)(C)OC(=O)N1CCC(=O)CC1.C[S+](C)(C)=O>>CC(C)(C)OC(=O)N1CCC2(CC1)CO2 -US20100009970A1,6,COC(=O)c1ccc2c(c1)[C@@H](N(C)C(=O)OC(C)(C)C)CC[C@H]2c1ccc(Cl)c(Cl)c1>>CN(C(=O)OC(C)(C)C)[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccc(C(=O)O)cc21 -US20040133008A1,2,Cc1ccc(C(=O)Nc2ccc3c(c2)CCN3)c(N2CCCCC2)n1.O=C(O)Cc1ccccn1>>Cc1ccc(C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2ccccn2)c(N2CCCCC2)n1 -US20090275753A1,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.c1ccc(-c2cc[nH]n2)cc1>>CC(C)(C)OC(=O)N1CCC(n2ccc(-c3ccccc3)n2)CC1 -US20140066459A1,3,CC(=O)N1c2ccc(Br)cc2[C@H](Nc2ccc(C#N)cn2)C[C@@H]1C.COCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COCCn1cc(-c2ccc3c(c2)[C@H](Nc2ccc(C#N)cn2)C[C@H](C)N3C(C)=O)cn1 -US06187952B1,9,O=C(Cl)c1ccc(F)c(Cl)c1>>O=C(Cl)c1ccc(F)cc1 -US20110166133A1,7,Fc1ccc(F)c(C2=NCCC2)c1>>Fc1ccc(F)c(C2CCCN2)c1 -US07560558B2,3,CCCC[Sn](CCCC)(CCCC)c1nccs1.COc1cc2nccc(Oc3ccc(C)nc3I)c2cc1OC>>COc1cc2nccc(Oc3ccc(C)nc3-c3nccs3)c2cc1OC -US06984644B2,2,CC(C)Cn1c(=O)n(C)c(=O)c2cc(Cc3ccc(N)cc3)sc21.COc1ccc(CCCC(=O)O)cc1OC>>COc1ccc(CCCC(=O)Nc2ccc(Cc3cc4c(=O)n(C)c(=O)n(CC(C)C)c4s3)cc2)cc1OC -US07906546B2,1,ClCc1nc(-c2ccccc2)no1.O=S([O-])c1ccccc1>>O=S(=O)(Cc1nc(-c2ccccc2)no1)c1ccccc1 -US07893046B2,3,C=CCC(NC(=O)c1c(Cl)cccc1Cl)C(=O)OC.Ic1ccc(N(Cc2ccccn2)c2ncccn2)cc1>>COC(=O)C(C/C=C/c1ccc(N(Cc2ccccn2)c2ncccn2)cc1)NC(=O)c1c(Cl)cccc1Cl -US20120101082A1,1,NC1CC1.O=CC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(CNC2CC2)CC1 -US09029399B2,2,Nc1ccnc(Cl)c1.O=C=NCCCl>>O=C(NCCCl)Nc1ccnc(Cl)c1 -US06683090B1,2,C/C(=C\c1ccccc1)C(=O)O.N[C@H]1CN2CCC1CC2>>C/C(=C\c1ccccc1)C(=O)N[C@H]1CN2CCC1CC2 -US08536183B2,6,Cc1cc(C#N)ccc1S(=O)(=O)N1CCN(C(=O)OC(C)(C)C)[C@H](C)C1>>Cc1cc(C#N)ccc1S(=O)(=O)N1CCN[C@H](C)C1 -US08211914B2,2,Nc1ccc(N2CCN(c3ncccn3)CC2)nc1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>O=C(Nc1ccc(N2CCN(c3ncccn3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US04414416,1,C=CCBr.CC(=O)c1cc(C(C)=O)c(O)cc1N>>C=CCOc1cc(N)c(C(C)=O)cc1C(C)=O -US20050203110A1,1,CCC(Br)c1nc2cccnc2c(=O)n1Cc1ccccc1.CN(C)CCN>>CCC(NCCN(C)C)c1nc2cccnc2c(=O)n1Cc1ccccc1 -US08084590B2,6,CCOC(=O)COCCOC(C)N=[N+]=[N-]>>CC(N=[N+]=[N-])OCCOCC(=O)O -US20110269741A1,1,CCOC(=O)c1cn([C@H](CO[Si](C)(C)C(C)(C)C)C(C)C)c2nc(OC)c(CBr)cc2c1=O.Oc1c(F)cc(F)cc1F>>CCOC(=O)c1cn([C@H](CO[Si](C)(C)C(C)(C)C)C(C)C)c2nc(OC)c(COc3c(F)cc(F)cc3F)cc2c1=O -US03950380,3,COC(=O)c1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1.Ic1ccccc1>>COC(=O)c1cc([N+](=O)[O-])c(-c2ccccc2)c([N+](=O)[O-])c1 -US08410107B2,3,Nc1cnc(OCC2CC2)c(Br)c1.OB(O)c1ccc(Cl)cc1>>Nc1cnc(OCC2CC2)c(-c2ccc(Cl)cc2)c1 -US20120196884A1,3,CN(c1ccc(NC(=O)Nc2ccccc2)cc1)S(=O)(=O)c1ccc(Br)s1.OB(O)c1cncnc1>>CN(c1ccc(NC(=O)Nc2ccccc2)cc1)S(=O)(=O)c1ccc(-c2cncnc2)s1 -US20130225584A1,3,CC(=O)Cl.Cc1ccc(O)cc1Br>>CC(=O)c1cc(C)c(Br)cc1O -US06084133,9,ClP(c1ccccc1)c1ccccc1>>c1ccc(Pc2ccccc2)cc1 -US20080153810A1,2,CN1CCN(c2n[nH]c3cc(C(=O)[O-])ccc23)CC1.NCc1ccc(Cl)cc1>>CN1CCN(c2n[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)ccc23)CC1 -US05160365,2,CC(C)OC(=O)c1ccccc1S(=O)(=O)N=C=O.COc1nc(N)nc(C(F)(F)F)n1>>COc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OC(C)C)nc(C(F)(F)F)n1 -US20060199853A1,2,CNOC.O=C(O)C1CCCCC1>>CON(C)C(=O)C1CCCCC1 -US20090247526A1,1,COc1ccc(Oc2ccnc(Cl)c2)cc1.Cc1csc(N)n1>>COc1ccc(Oc2ccnc(Nc3nc(C)cs3)c2)cc1 -US20090221555A1,1,COc1cc(N2CCN(C)CC2)ccc1Nc1nc(Cl)ncc1Cl.COc1cc2c(cc1N)CCN(CC(N)=O)CC2>>COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccc(N4CCN(C)CC4)cc3OC)n1)CCN(CC(N)=O)CC2 -US20100204196A1,7,COc1cc(N2CCC(N3CC[C@@H](F)C3)CC2)ccc1[N+](=O)[O-]>>COc1cc(N2CCC(N3CC[C@@H](F)C3)CC2)ccc1N -US20090221555A1,1,C1COCCN1.O=[N+]([O-])c1ccc(F)cc1O>>O=[N+]([O-])c1ccc(N2CCOCC2)cc1O -US20020183285A1,3,C#C[Si](C)(C)C.CC1(C)CC(C)(C)c2cc(Br)cc(C3CC3)c2O1>>CC1(C)CC(C)(C)c2cc(C#C[Si](C)(C)C)cc(C3CC3)c2O1 -US06432950B1,1,NCc1ccccc1.O=[N+]([O-])c1cc2c(Cl)nc(Cl)nc2s1>>O=[N+]([O-])c1cc2c(NCc3ccccc3)nc(Cl)nc2s1 -US07572805B2,9,CCc1cc(Cl)c2c(c1)[C@H]1CNC[C@@H]1NC2=O>>CCc1ccc2c(c1)[C@H]1CNC[C@@H]1NC2=O -US20050065164A1,6,CC1(C)CN(Cc2ccccc2)CCC1N>>CC1(C)CNCCC1N -US07504432B2,1,CCI.CCN1CCC(OC(=O)[C@](O)(c2ccc(Cl)cc2)[C@@H]2CCC(F)(F)C2)CC1>>CC[N+]1(CC)CCC(OC(=O)[C@](O)(c2ccc(Cl)cc2)[C@@H]2CCC(F)(F)C2)CC1 -US05017724,4,Cc1cc(C)c2c(c1O)C(N)C1CCCCC21.O=C(Cl)CCCCl>>Cc1cc(C)c2c(c1O)C(N1CCCC1=O)C1CCCCC21 -US20130090323A1,1,COC1CNC1.COc1cncc(-c2cnc(Cl)cc2N)c1>>COc1cncc(-c2cnc(N3CC(OC)C3)cc2N)c1 -US06890947B2,3,CCOC(=O)C(OCC)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Cc1cc2cc(C=O)ccc2[nH]1>>CCOC(=O)/C(=C/c1ccc2[nH]c(C)cc2c1)OCC -US20120077828A1,6,CC(C)(C)OC(=O)N1CCC(n2cc(-c3ccc4c(c3)CCN4C(=O)Cc3cc(F)ccc3F)c3c(N)ncnc32)CC1>>Nc1ncnc2c1c(-c1ccc3c(c1)CCN3C(=O)Cc1cc(F)ccc1F)cn2C1CCNCC1 -US09067905B2,6,COC(=O)c1c(CS(=O)(=O)c2ccccc2/C=C\CN2CCCCC2)ccc(-c2ccoc2)c1OC>>COc1c(-c2ccoc2)ccc(CS(=O)(=O)c2ccccc2/C=C\CN2CCCCC2)c1C(=O)O -US20130281460A1,3,CSc1nc(Br)cn2c(I)cnc12.O=C(NC1CC1)c1ccc(B(O)O)cc1>>CSc1nc(Br)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 -US20060058361A1,6,CCC(O)c1ccc(C(OC)OC)c(Oc2ccc(Cl)c(C)c2C)c1>>CCC(O)c1ccc(C=O)c(Oc2ccc(Cl)c(C)c2C)c1 -US20130090323A1,1,COc1cncc(-c2cnc(N3CCOCC3)cc2N)c1.Cc1c(-c2ccccn2)nc2cccc(F)c2c1Cl>>COc1cncc(-c2cnc(N3CCOCC3)cc2Nc2c(C)c(-c3ccccn3)nc3cccc(F)c23)c1 -US08765940B2,4,CCOC(=O)C(C)C(C)=O.Nc1ccc(Cl)cc1>>Cc1nc2ccc(Cl)cc2c(O)c1C -US20150111935A1,9,CCCCCCC/C=C/C=C/CN=[N+]=[N-]>>CCCCCCC/C=C/C=C/CN -US20150111877A1,6,Cc1cccc(S(=O)(=O)N2C[C@H](C)Oc3ncc(NC(=O)OC(C)(C)C)cc32)c1>>Cc1cccc(S(=O)(=O)N2C[C@H](C)Oc3ncc(N)cc32)c1 -US20030236288A1,2,C1COCCN1.O=S(=O)(Cl)c1ccc(F)cc1>>O=S(=O)(c1ccc(F)cc1)N1CCOCC1 -US04966967,7,O=C(Cc1ccc(-n2ccnc2)cc1)N1CCOc2ccc(-n3ccnc3)cc2OCC1>>c1cn(-c2ccc(CCN3CCOc4ccc(-n5ccnc5)cc4OCC3)cc2)cn1 -US20120208798A1,7,CC(C)(C)OC(=O)Cn1cnc(-c2ccc([N+](=O)[O-])cc2)c1>>CC(C)(C)OC(=O)Cn1cnc(-c2ccc(N)cc2)c1 -US20050222176A1,2,CN.O=C(O)c1cccc(CN2CCC(Nc3ncnc4sc(Cl)cc34)CC2)c1>>CNC(=O)c1cccc(CN2CCC(Nc3ncnc4sc(Cl)cc34)CC2)c1 -US20070049618A1,2,NC1CC1.O=C(O)CNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>O=C1CCC(N2C(=O)c3cccc(NCC(=O)NC4CC4)c3C2=O)C(=O)N1 -US20040110746A1,1,CCC(CC)N1CCN(C(=O)c2ccc(C=O)cc2)CC1.CNC>>CCC(CC)N1CCN(C(=O)c2ccc(CN(C)C)cc2)CC1 -US20100274051A1,1,Nc1cc(Cl)cc(Cl)c1.O=Cc1cc(Br)ccc1O>>Oc1ccc(Br)cc1C=Nc1cc(Cl)cc(Cl)c1 -US20110263607A1,6,CC(C)(C)OC(=O)CONC(=O)NCc1ccncc1>>O=C(O)CONC(=O)NCc1ccncc1 -US06437138B1,6,CC(C)(C)OC(=O)N1CC[C@H]1COc1cnc(Cl)c(CNC(=O)c2cccc([N+](=O)[O-])c2)c1>>O=C(NCc1cc(OC[C@@H]2CCN2)cnc1Cl)c1cccc([N+](=O)[O-])c1 -US06313310B1,3,C#CC(O)c1ccc(OC)cc1.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1ccc(C(O)C#Cc2cccc3c2/C(=C/c2[nH]ccc2OC)C(=O)N3)cc1 -US04307230,2,CC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(N)C2SC1.CON=C(C(=O)OC(=O)C(=NOC)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C)CSC12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US07378417B2,2,Nc1cccc(S(N)(=O)=O)c1.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)c(Cl)c3)nc12>>NS(=O)(=O)c1cccc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)c(Cl)c4)nc23)c1 -US20090029958A1,2,C[C@H](COCC(=O)O)c1ccccc1.OCC1CCNCC1>>C[C@H](COCC(=O)N1CCC(CO)CC1)c1ccccc1 -US05559236,7,CC1(C)COC(c2ccccc2-c2ccc(C(=O)O)cc2)=N1>>CC1(C)COC(c2ccccc2-c2ccc(CO)cc2)=N1 -US05140046,1,CCOC(=O)CS.ClCCCBr>>CCOC(=O)CSCCCCl -US20150236268A1,1,Brc1ccc(I)cc1.c1ccc(-c2ccc(Nc3ccc(-c4ccccc4)cc3)cc2)cc1>>Brc1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)cc1 -US06337326B1,6,COc1ccccc1N1CCCN(C(=O)OC(C)(C)C)CC1>>COc1ccccc1N1CCCNCC1 -US20150152092A1,3,C=C(C)B1OC(C)(C)C(C)(C)O1.COC(=O)c1cc(-c2c(Br)cnn2C)c(C)s1>>C=C(C)c1cnn(C)c1-c1cc(C(=O)OC)sc1C -US20150191439A1,1,COc1ccc(C(C)=O)cc1.NC12CC3CC(CC(C3)C1)C2>>COc1ccc(C(C)NC23CC4CC(CC(C4)C2)C3)cc1 -US07521461B2,1,COC(=O)c1ccccc1COc1cccc(CCO)c1.Oc1ccc(OCc2ccccc2)cc1>>COC(=O)c1ccccc1COc1cccc(CCOc2ccc(OCc3ccccc3)cc2)c1 -US08273769B2,7,CS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1>>CS(=O)(=O)c1ccc(Cl)c(N)c1 -US20030236297A1,3,C#CCCCC1CCCCC1.C[C@@H]1COC(=O)N1CCc1ccc(Br)s1>>C[C@@H]1COC(=O)N1CCc1ccc(C#CCCCC2CCCCC2)s1 -US07491748B2,7,CCOC(=O)C=Cc1ccc(COc2ccccc2)cc1N(C)CCc1ccc2ccccc2c1>>CCOC(=O)CCc1ccc(COc2ccccc2)cc1N(C)CCc1ccc2ccccc2c1 -US20150166480A1,2,O=C(O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2)c(F)c1.OC[C@H]1CCCN1>>O=C(c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2)c(F)c1)N1CCC[C@@H]1CO -US20100087471A1,1,Fc1ccc(CBr)cc1.NNc1ccc(F)cc1>>NN(Cc1ccc(F)cc1)c1ccc(F)cc1 -US20090029947A1,7,CCOC(=O)CCc1ccc(F)c(OC)c1>>COc1cc(CCCO)ccc1F -US20090298899A1,2,CCOC(=O)Cc1cccc(N)c1.O=C(O)c1cccc(Br)c1>>CCOC(=O)Cc1cccc(NC(=O)c2cccc(Br)c2)c1 -US20090099162A2,1,CC(C)(C)OC(=O)N1CC2CNCC(C1)O2.CS(=O)(=O)OCCN(CCCc1ccc(C#N)cc1)S(C)(=O)=O>>CC(C)(C)OC(=O)N1CC2CN(CCN(CCCc3ccc(C#N)cc3)S(C)(=O)=O)CC(C1)O2 -US20130035310A1,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.c1ccc(C2CCNCC2)cc1>>O=C(N1CCC(c2ccccc2)CC1)C(F)(F)F -US08912329B2,2,O=C(Cl)CCc1ccccc1.c1ccc(C2CCN2)cc1>>O=C(CCc1ccccc1)N1CCC1c1ccccc1 -US06924292B2,1,C=C(C)CCl.Cc1ccccc1O>>C=C(C)COc1ccccc1C -US20150246912A1,6,CCOC(=O)Cc1nc(C(C)(C)C)nn1CCOC>>COCCn1nc(C(C)(C)C)nc1CC(=O)O -US08680159B2,6,CN(C)c1ccc(N2CCC(N(C)C(=O)OCc3ccccc3)CC2)cn1>>CNC1CCN(c2ccc(N(C)C)nc2)CC1 -US05599813,6,CCOC(=O)CCC1=C(C(=O)OC(C)(C)C)SC2=NCCCN21>>CCOC(=O)CCC1=C(C(=O)O)SC2=NCCCN21 -US05852212,7,CCCCC/C=C(\Br)C(=O)O>>CCCCCC[C@@H](Br)C(=O)O -US20120040954A1,4,COc1cc(N)c(C(N)=O)c(OC)c1.Cc1cc(C=O)cc(C)c1OC[C@@H]1CCC(=O)N1>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OC[C@@H]4CCC(=O)N4)c(C)c3)nc2c1 -US20050261331A1,1,CI.CN(C)CC(O)COc1ccc(Br)cc1>>COC(COc1ccc(Br)cc1)CN(C)C -US08993614B2,2,CC(C)(C)OC(=O)N1CCNCC1.CC(Cl)OC(=O)Cl>>CC(Cl)OC(=O)N1CCN(C(=O)OC(C)(C)C)CC1 -US07767677B2,1,CI.O=C(c1ccccc1C(F)(F)F)N1CCN(c2ccc(N3CCNC3=O)nn2)CC1>>CN1CCN(c2ccc(N3CCN(C(=O)c4ccccc4C(F)(F)F)CC3)nn2)C1=O -US07608629B2,1,CN1CCC(O)CC1.O=[N+]([O-])c1cc(F)cc(F)c1>>CN1CCC(Oc2cc(F)cc([N+](=O)[O-])c2)CC1 -US20080312281A1,6,CC(C)(C)OC(=O)N1CCC(CCCCc2ccncc2)CC1>>c1cc(CCCCC2CCNCC2)ccn1 -US20120225857A1,3,CCN(C)S(=O)(=O)c1ccc([Sn](C)(C)C)nc1.Nc1ncc(Br)cc1-c1cc2c(s1)C(=O)NC2>>CCN(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc4c(s3)C(=O)NC4)c2)nc1 -US20040122057A1,6,CCOC(=O)C(OC)c1c(F)ccc(O)c1F>>COC(C(=O)O)c1c(F)ccc(O)c1F -US08304557B2,2,Cn1cc(C(=O)O)c(C2CC2)n1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>Cn1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)c(C2CC2)n1 -US20110263589A1,1,COC(=O)Cc1ccccc1O.COc1cc(F)ccc1-c1ccc2c(c1CO)C(C)=CC(C)(C)N2>>COC(=O)Cc1ccccc1OCc1c(-c2ccc(F)cc2OC)ccc2c1C(C)=CC(C)(C)N2 -US05741819,2,NC1CN2CCC1CC2.O=C(O)c1cccc(NS(=O)(=O)c2ccccc2)c1>>O=C(NC1CN2CCC1CC2)c1cccc(NS(=O)(=O)c2ccccc2)c1 -US20070179173A1,2,CC(C)c1ccc(N)cc1.COc1ccc(CC2SC(=O)NC2=O)c2c1N(Cc1ccc(C(=O)O)cc1)C(=O)CC2>>COc1ccc(CC2SC(=O)NC2=O)c2c1N(Cc1ccc(C(=O)Nc3ccc(C(C)C)cc3)cc1)C(=O)CC2 -US20060241142A1,1,COCCBr.COc1c(C#N)cc2ccccc2c1C(=O)NCC1(c2ccc(Cl)cc2)CCNCC1>>COCCN1CCC(CNC(=O)c2c(OC)c(C#N)cc3ccccc23)(c2ccc(Cl)cc2)CC1 -US04575503,9,COc1ccc2c(c1)N(CC(=O)O)C(=O)C(N=[N+]=[N-])CC2>>COc1ccc2c(c1)N(CC(=O)O)C(=O)C(N)CC2 -US05618808,7,CC(C)(C)OC(=O)N[C@H](COc1ccccc1[N+](=O)[O-])C(=O)O>>CC(C)(C)OC(=O)N[C@H](COc1ccccc1N)C(=O)O -US05994368,1,Cc1ccc2cccc(O)c2n1.O=[N+]([O-])c1ccc(Cl)c(CCl)c1Cl>>Cc1ccc2cccc(OCc3c(Cl)ccc([N+](=O)[O-])c3Cl)c2n1 -US20070293521A1,2,CC(C)(N)CO.COC(=O)c1cc2cc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)ccc2o1>>CC(C)(CO)NC(=O)c1cc2cc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)ccc2o1 -US06255333B1,3,C=C[Sn](CCCC)(CCCC)CCCC.FC(F)(F)c1cc(Cl)c(-n2cc(I)c(-c3ccccc3)n2)c(Cl)c1>>C=Cc1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1-c1ccccc1 -US20040157836A1,7,CC(C)(C)OC(=O)N1CCN(C(=O)CC#N)CC1>>CC(C)(C)OC(=O)N1CCN(C(=O)CCN)CC1 -US20130092879A1,5,Brc1ccc2[nH]c3ccccc3c2c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1c2ccccc2c2cc(Br)ccc21 -US20150232480A1,6,COC(=O)[C@@H](OC(C)(C)C)c1c(C)c(C(C)O)c2nc3cn2c1N1CCC(C)(CC1)OCCCC[C@H](C)Oc1ccc(F)cc1-c1cccc-3c1>>Cc1c([C@H](OC(C)(C)C)C(=O)O)c2n3cc(nc3c1C(C)O)-c1cccc(c1)-c1cc(F)ccc1O[C@@H](C)CCCCOC1(C)CCN2CC1 -US05622954,8,CC(C)(CO)c1ccc(Cl)cc1>>CC(C)(C=O)c1ccc(Cl)cc1 -US09079876B2,1,CSc1ccc(N)cn1.O=Cc1ccccc1>>CSc1ccc(N=Cc2ccccc2)cn1 -US04337353,7,Cc1c(C=CCCCCCCCCCC(=O)O)cccc1C(=O)c1ccc(Cl)cc1>>Cc1c(CCCCCCCCCCCC(=O)O)cccc1C(=O)c1ccc(Cl)cc1 -US20090069282A1,3,C#Cc1ccc2c(c1)c(C)c(C(=O)OCC)n2CCN1CCCC1.Clc1ccc(-c2ccc(I)nc2)cc1>>CCOC(=O)c1c(C)c2cc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)ccc2n1CCN1CCCC1 -US04297096,8,CCCC=CC/C=C/CO>>CCCC=CC/C=C/C=O -US20110046161A1,6,C=CCn1c(O[C@@H]2C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C2)cccc1=O>>C=CCn1c(O[C@H]2C[NH2+][C@H](C(=O)OC)C2)cccc1=O -US20020016328A1,7,CCC(CC)Oc1nc(C)nc(Nc2c(C)cc(C)cc2C)c1C(=O)O>>CCC(CC)Oc1nc(C)nc(Nc2c(C)cc(C)cc2C)c1CO -US20140336185A1,7,CCCCCCCOc1ccc(C(=O)Oc2ccc(CN(CC(=O)OC(C)(C)C)C(=O)c3ccc(NC(=O)Cc4ccc(OC)cc4C(F)(F)F)cc3)cc2)cc1>>COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)OC(C)(C)C)Cc3ccc(O)cc3)cc2)c(C(F)(F)F)c1 -US20100130489A1,1,Nc1ccccn1.O=Cc1cc2c(cc1C(F)(F)F)nc(NCCCO)c1nccn12>>OCCCNc1nc2cc(C(F)(F)F)c(CNc3ccccn3)cc2n2ccnc12 -US20090093484A1,3,C#Cc1ccccn1.COC(=O)COc1ccc(OC/C=C(/c2ccc(F)cc2)c2ccc(I)cc2)cc1C>>COC(=O)COc1ccc(OC/C=C(/c2ccc(F)cc2)c2ccc(C#Cc3ccccn3)cc2)cc1C -US20090264416A1,6,COC(=O)c1ccc(OC)c(CN2CCN(C(=O)c3ccc(NC(=O)Nc4ccccc4)cc3)CC2)c1>>COc1ccc(C(=O)O)cc1CN1CCN(C(=O)c2ccc(NC(=O)Nc3ccccc3)cc2)CC1 -US08338605B2,6,CC(=O)Nc1ccc(COC(C)=O)cc1>>CC(=O)Nc1ccc(CO)cc1 -US20140336190A1,3,CON(C)C(=O)c1cc(-c2c(C)noc2C)cc2[nH]c(C3CC3)nc12.C[Mg+]>>CC(=O)c1cc(-c2c(C)noc2C)cc2[nH]c(C3CC3)nc12 -US04297129,2,O=C(Cl)c1cccc2ccccc12.O=c1cnn(CO)c(=O)[nH]1>>O=C(OCn1ncc(=O)[nH]c1=O)c1cccc2ccccc12 -US20090012077A1,2,O=C(O)[C@@H]1CCCC[C@H]1C(=O)O>>O=C1OC(=O)[C@@H]2CCCC[C@@H]12 -US20070129416A1,2,CCOc1cc(C(C)(C)C)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1.O=C(Cl)c1ccccc1>>CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)c1ccccc1 -US08586614B2,2,CC(=O)Nc1ncc(S(=O)(=O)Cl)s1.CCOC(=O)CN>>CCOC(=O)CNS(=O)(=O)c1cnc(NC(C)=O)s1 -US04294835,8,CC(=O)Oc1ccccc1C(=O)NC(SC(C)C)C(Cl)(Cl)Cl.OO>>CC(=O)Oc1ccccc1C(=O)NC(S(=O)C(C)C)C(Cl)(Cl)Cl -US08466289B2,7,Cc1c(Nc2ccc(Br)cc2F)c([N+](=O)[O-])c2n(c1=O)CCN2C(=O)OC(C)(C)C>>Cc1c(Nc2ccc(Br)cc2F)c(N)c2n(c1=O)CCN2C(=O)OC(C)(C)C -US08921373B2,6,CC(C)(C)OC(=O)N1CCC(F)(c2ncc(C[C@@H](O)CO)cc2F)CC1>>OC[C@H](O)Cc1cnc(C2(F)CCNCC2)c(F)c1 -US20100216750A1,6,CC(C)(C)OC(=O)CCCOCCc1ccccc1>>O=C(O)CCCOCCc1ccccc1 -US20150141406A1,7,NC(=O)c1cc(-c2nn(C3CCC(=O)CC3)c3cc[nH]c(=O)c23)cs1>>NC(=O)c1cc(-c2nn([C@@H]3CC[C@@H](O)CC3)c3cc[nH]c(=O)c23)cs1 -US08008325B2,6,CCOC(=O)C(CS)c1ccc(NC(=N)N)cc1>>N=C(N)Nc1ccc(C(CS)C(=O)O)cc1 -US20070054918A1,1,C=CCN1CCNCC1.O=[N+]([O-])c1ccc(Br)cn1>>C=CCN1CCN(c2ccc([N+](=O)[O-])nc2)CC1 -US20150266824A1,6,CC(C)(C)OC(=O)N1C[C@H](C2CCCCC2)C[C@H]1[C@@H](O)c1c(Cl)cncc1Cl>>O[C@@H](c1c(Cl)cncc1Cl)[C@@H]1C[C@@H](C2CCCCC2)CN1 -US07622487B2,2,CN=C=O.FC(F)(F)c1cc(CO[C@H]2CCNC[C@H]2C(c2ccccc2)c2ccccc2)cc(C(F)(F)F)c1>>CNC(=O)N1CC[C@H](OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](C(c2ccccc2)c2ccccc2)C1 -US04436753,7,COc1cc(C)c(C(=O)CCCCCCCCCCOC(C)=O)c(O)c1OC>>COc1cc(C)c(C(=O)CCCCCCCCCCO)c(O)c1OC -US04521601,7,c1ccc2c(c1)CCNC2>>C1=CCC2CCNCC2=C1 -US20080153850A1,3,CC(C)(C)OC(=O)[C@@H]1CCCN1c1ncccc1Br.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(B(O)O)ccc1Cl>>CC(C)(C)OC(=O)[C@@H]1CCCN1c1ncccc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 -US05886043,2,CC(C(=O)O)C(C)C(=O)O>>CC1C(=O)OC(=O)C1C -US20120202856A1,4,Cn1nc(C(C)(C)C)cc1C(=O)O.Nc1ccc(Br)cc1N>>Cn1nc(C(C)(C)C)cc1-c1nc2cc(Br)ccc2[nH]1 -US20140243336A1,1,Cc1cc(C(=O)N(C)C)cc(Cl)n1.N=C(c1ccccc1)c1ccccc1>>Cc1cc(C(=O)N(C)C)cc(N=C(c2ccccc2)c2ccccc2)n1 -US06875884B1,6,CC(=O)OCCCCN(CCCNC(=O)Nc1ccc(Br)cc1)C1CCCc2ccccc21>>O=C(NCCCN(CCCCO)C1CCCc2ccccc21)Nc1ccc(Br)cc1 -US20100120770A1,7,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCC(CN)(c2ccccc2)CC1 -US20140200227A1,6,COc1ccc(Cn2ncc3c(N4CCC[C@H](NC(=O)OC(C)(C)C)C4)c(NC(=O)OC(C)(C)C)cnc32)cc1>>COc1ccc(Cn2ncc3c(N4CCC[C@H](NC(=O)OC(C)(C)C)C4)c(N)cnc32)cc1 -US20140200227A1,2,C[C@H]1CN(c2c(N)cnc3c2CCO3)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C.O=C(O)c1ccc(F)c(-c2c(F)cccc2F)n1>>C[C@H]1CN(c2c(NC(=O)c3ccc(F)c(-c4c(F)cccc4F)n3)cnc3c2CCO3)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C -US20090227628A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COc1ccccc1CNc1ccc2c(Br)cccc2n1>>C=Cc1cccc2nc(NCc3ccccc3OC)ccc12 -US09156827B2,8,COc1ccc2[nH]nc(CO)c2c1>>COc1ccc2[nH]nc(C=O)c2c1 -US20110281884A1,2,CNOC.O=C(O)c1cc(Cl)c2ccnn2c1-c1cccc(F)c1>>CON(C)C(=O)c1cc(Cl)c2ccnn2c1-c1cccc(F)c1 -US20120177681A1,1,CCOP(=O)(OCC)C(F)(F)CCOCCBr.COc1cc(O)ccc1C=O>>CCOP(=O)(OCC)C(F)(F)CCOCCOc1ccc(C=O)c(OC)c1 -US20110224155A1,2,CCCC(=O)NC(C)(C)COc1cccc(N)c1C#N.NS(=O)(=O)Cl>>CCCC(=O)NC(C)(C)COc1cccc(NS(N)(=O)=O)c1C#N -US20060122168A1,7,O=C(O)C(C(Oc1ccc(F)cc1[N+](=O)[O-])C(F)(F)F)N(Cc1ccccc1)Cc1ccccc1>>Nc1cc(F)ccc1OC(C(C(=O)O)N(Cc1ccccc1)Cc1ccccc1)C(F)(F)F -US20030153605A1,2,CC(C)(C)N=C=S.COc1cnccc1CC(N)CO>>COc1cnccc1CC(CO)NC(=S)NC(C)(C)C -US20140275172A1,6,CCCc1cc2cc(C(=O)N(C)C)cc(COc3ccc(CCC(=O)OCC)c(C)c3C)c2o1>>CCCc1cc2cc(C(=O)N(C)C)cc(COc3ccc(CCC(=O)O)c(C)c3C)c2o1 -US07915267B2,9,CC(C)(C)OC(=O)N1CCN(c2cccc(Br)c2)CC1.[C-]#N>>CC(C)(C)OC(=O)N1CCN(c2cccc(C#N)c2)CC1 -US20080194616A1,1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.CCCOc1nc2ccccn2c(=O)c1-c1ccc(Cl)cc1>>CCCOc1nc2ccccn2c(=O)c1-c1ccc(N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1 -US08557832B2,6,CC(C)(C)OC(=O)N[C@H]1CCCC[C@@H]1n1cnc2c(cc(Cc3ccc(Cl)nc3)c3ccccc32)c1=O>>N[C@H]1CCCC[C@@H]1n1cnc2c(cc(Cc3ccc(Cl)nc3)c3ccccc32)c1=O -US04267338,2,CCOC(=O)CNc1c(CC)cccc1CC.NN>>CCc1cccc(CC)c1NCC(=O)NN -US20120010191A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cc(F)cc1N1CCn2c(cc3c2CCCC3)C1=O.Cn1nc(Cl)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O>>CC(=O)OCc1c(-c2cc(Nc3ccc(N4CCN(C5COC5)CC4)cn3)c(=O)n(C)n2)cc(F)cc1N1CCn2c(cc3c2CCCC3)C1=O -US05534515,1,Cc1c([N+](=O)[O-])c2cnnc(Cl)c2n1CC(C)C.OCc1ccccc1>>Cc1c([N+](=O)[O-])c2cnnc(OCc3ccccc3)c2n1CC(C)C -US20120130117A1,3,COc1ccccc1.O=C(Cl)c1ccc(F)c(F)c1>>COc1ccc(C(=O)c2ccc(F)c(F)c2)cc1 -US20130317024A1,3,COC(=O)c1cc(Br)n(C(C)C)c1.COc1ncc(B(O)O)c(OC)n1>>COC(=O)c1cc(-c2cnc(OC)nc2OC)n(C(C)C)c1 -US20090281139A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(CNCc1ccc(Br)cc1)OCc1ccccc1>>CC(C)(C)OC(=O)N(CC(=O)OCc1ccccc1)Cc1ccc(Br)cc1 -US20110135601A1,1,Cc1cc(N)cc2c1CCN(C)C2.Cc1cccc(Cl)c1-n1c(=O)[nH]c2nc(Cl)ncc2c1=N>>Cc1cc(Nc2ncc3c(=N)n(-c4c(C)cccc4Cl)c(=O)[nH]c3n2)cc2c1CCN(C)C2 -US20150174110A1,2,CCOc1ncc(-c2nc(C(=O)OC)c(O)c3cc(-c4ccccc4)c(=O)n(Cc4ccccc4)c23)cn1.NCCC(=O)O>>CCOc1ncc(-c2nc(C(=O)NCCC(=O)O)c(O)c3cc(-c4ccccc4)c(=O)n(Cc4ccccc4)c23)cn1 -US08846739B2,7,CC(C)(c1ccc(Cl)c(Cl)c1)c1cnc(C=O)n1-c1ccc(F)cc1>>CC(C)(c1ccc(Cl)c(Cl)c1)c1cnc(CO)n1-c1ccc(F)cc1 -US20110263647A1,7,CC(F)(F)c1ccc(C(=O)OCc2ccccc2)cn1>>CC(F)(F)c1ccc(CO)cn1 -US06197905B1,1,C=C(CBr)c1ccccc1.CCOP(OCC)OCC>>C=C(CP(=O)(OCC)OCC)c1ccccc1 -US20040254182A1,2,CC(=O)Nc1ccc(O)cc1.CC(C)OC(=O)C(OC(=O)Cl)OC(=O)C(C)C>>CC(=O)Nc1ccc(OC(=O)OC(OC(=O)C(C)C)C(=O)OC(C)C)cc1 -US20120157479A1,3,CC(C)(C)OC(=O)N1C[C@H](C=O)[C@@H](O[Si](C)(C)C(C)(C)C)C1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C -US20100080770A1,1,C=Cc1cc2cc([C@]3(O)C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C3)ccc2cc1N(C)C.CI>>C=Cc1cc2cc([C@]3(OC)C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C3)ccc2cc1N(C)C -US06492416B1,8,CSc1ccc(C2=C(c3cc(F)cc(F)c3)C(=O)C(C)(C)O2)cc1C.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C2=C(c3cc(F)cc(F)c3)C(=O)C(C)(C)O2)ccc1S(C)=O -US20150094328A1,3,CCCC[Sn](CCCC)(CCCC)c1nccn1C.O=C(N[C@H]1CCCC[C@@H]1O)c1cn(Cc2ccc(Br)cc2)c2cccnc12>>Cn1ccnc1-c1ccc(Cn2cc(C(=O)N[C@H]3CCCC[C@@H]3O)c3ncccc32)cc1 -US20080131367A1,7,O=c1cc(-c2ccc([N+](=O)[O-])cc2)oc2ccc(Br)cc12>>Nc1ccc(-c2cc(=O)c3cc(Br)ccc3o2)cc1 -US20080255059A1,5,COC(=O)C(F)(F)F.N[C@@H](Cc1ccc(C(=O)c2ccccc2)cc1)C(=O)O>>O=C(c1ccccc1)c1ccc(C[C@H](NC(=O)C(F)(F)F)C(=O)O)cc1 -US20140057896A1,7,CCOC(=O)c1cc2c(n1CC#N)C1CCC2C1>>CCOC(=O)c1cc2c(n1CCN)C1CCC2C1 -US20140134133A1,6,COc1ncc(-c2ccc3ncc(C#C[Si](C)(C)C)n3n2)cc1NS(=O)(=O)c1ccc(F)cc1>>C#Cc1cnc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4)c3)nn12 -US20070232581A1,6,CCOC(=O)CC(=NOC)c1ccc(OC)cc1>>CON=C(CC(=O)O)c1ccc(OC)cc1 -US04303655,2,CCOC(=O)C(=O)c1csc(N)n1.CN=C=S>>CCOC(=O)C(=O)c1csc(NC(=S)NC)n1 -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1sc(-c2ccccc2)cc1NC(=O)Nc1c(Cl)cccc1Cl)C1CCCCC1>>O=C(Nc1cc(-c2ccccc2)sc1C(=O)N[C@H](C(=O)O)C1CCCCC1)Nc1c(Cl)cccc1Cl -US20150183801A1,1,C1OCC2COCC1N2.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2C3COCC2COC3)c(Br)c1 -US07262301B1,1,COCOc1cc(OC)c(OC)cc1-c1nc2c(CBr)cccc2o1.NCc1ccccn1>>COCOc1cc(OC)c(OC)cc1-c1nc2c(CNCc3ccccn3)cccc2o1 -US20140275241A1,9,C[C@@]12CC[C@H]3C[C@H]4C[C@H](O)CC[C@@H]4C[C@@H]3[C@H]1CC(=O)[C@H]2O>>C[C@@]12CC[C@H]3C[C@H]4C[C@H](O)CC[C@@H]4C[C@@H]3[C@H]1CC(=O)C2 -US08293902B2,1,COc1cc2c(Cl)ncnc2cc1O.O=C1CNC(=O)N1CCCO>>COc1cc2c(Cl)ncnc2cc1OCCCN1C(=O)CNC1=O -US20040102450A1,1,C[C@H]1C(=O)NCCN1C(=O)OCc1ccccc1.Clc1ccnc2cc(CBr)ccc12>>C[C@H]1C(=O)N(Cc2ccc3c(Cl)ccnc3c2)CCN1C(=O)OCc1ccccc1 -US20120016129A1,7,COC(=O)c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1>>OCc1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1 -US20120316147A1,2,CNC(=O)[C@@H](N)CC(C)C.O=C(O)c1ccc(C2CC2)c(OCC2CCCO2)n1>>CNC(=O)[C@H](CC(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1 -US20140315911A1,1,CC(C)CCn1c(=O)c(=O)[nH]c2cnc(Cl)nc21.OB(O)c1ccccc1>>CC(C)CCn1c(=O)c(=O)n(-c2ccccc2)c2cnc(Cl)nc21 -US20140249104A1,1,CC(C)(C)[S@](N)=O.CC[Si](CC)(CC)c1cc(Br)nc(C(=O)C(F)F)c1F>>CC[Si](CC)(CC)c1cc(Br)nc(/C(=N\[S@](=O)C(C)(C)C)C(F)F)c1F -US20120010189A1,1,CCC1(O)CNC1.Cc1cc(C=O)ccc1OC1CN(C(=O)c2nnc(-c3ccccc3)o2)C1>>CCC1(O)CN(Cc2ccc(OC3CN(C(=O)c4nnc(-c5ccccc5)o4)C3)c(C)c2)C1 -US20100168419A1,2,COC(=O)CN.O=C(Cl)c1ccccc1Cl>>COC(=O)CNC(=O)c1ccccc1Cl -US04963564,1,O=C(CBr)c1ccc(O)c(CO)c1.c1ccc(CNCCCCCCOCCCc2ncccc2OCc2ccccc2)cc1>>O=C(CN(CCCCCCOCCCc1ncccc1OCc1ccccc1)Cc1ccccc1)c1ccc(O)c(CO)c1 -US20120202794A1,2,CC=C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)c1noc(-c2ccc(F)cc2)n1>>C/C=C/[C@H]1CN(C(=O)c2noc(-c3ccc(F)cc3)n2)[C@@H](CC(C)C)C(=O)N1 -US20150087639A1,7,CC(C)CN(CC(C)C)c1ccc([N+](=O)[O-])cc1F>>CC(C)CN(CC(C)C)c1ccc(N)cc1F -US07915274B2,1,CC(C)(C)Oc1nccnc1C=O.CC1(C(=O)Cc2ccccc2F)CCNCC1>>CC(C)(C)Oc1nccnc1CN1CCC(C)(C(=O)Cc2ccccc2F)CC1 -US20020188120A1,6,CCOC(=O)C1(S(=O)(=O)c2ccc(OC)cc2)CCN(Cc2ccc(-c3cccs3)cc2)CC1>>COc1ccc(S(=O)(=O)C2(C(=O)O)CCN(Cc3ccc(-c4cccs4)cc3)CC2)cc1 -US20100216813A1,2,N#Cc1ccc(N(Cc2cc(Cl)ccc2Cl)[C@H]2CCNC2)cc1Cl.O=S(=O)(Cl)Cc1ccccc1>>N#Cc1ccc(N(Cc2cc(Cl)ccc2Cl)[C@H]2CCN(S(=O)(=O)Cc3ccccc3)C2)cc1Cl -US20130079303A1,1,COc1ccc(B(O)O)cn1.Nc1ncc(Cl)nc1Br>>COc1ccc(Nc2ncc(Cl)nc2Br)cn1 -US08354411B2,8,CSc1cccc(-n2ccc(=O)c(-c3ccnn3-c3ccccc3)n2)c1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cccc(-n2ccc(=O)c(-c3ccnn3-c3ccccc3)n2)c1 -US20130029980A1,6,CC(C)c1ccc(NC(=O)C(F)(F)F)c([N+](=O)[O-])c1>>CC(C)c1ccc(N)c([N+](=O)[O-])c1 -US05763450,9,NO.O=C(c1ccccn1)c1ccccn1>>ON=C(c1ccccn1)c1ccccn1 -US07176210B2,1,CC(C)(C)N1CC(O)C1.Cc1cc(Cl)n2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2n1>>Cc1cc(OC2CN(C(C)(C)C)C2)n2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2n1 -US20150197522A1,1,CCC(Br)C(=O)N1c2ccccc2Sc2ccccc21.Sc1nnc2c(n1)[nH]c1ccccc12>>CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)N1c2ccccc2Sc2ccccc21 -US08927711B2,7,NC(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>NC(=O)c1ccc(C(F)(F)F)cc1N -US20100317657A1,3,CC1(C)OB(c2cnn(CCOC3CCCCO3)c2)OC1(C)C.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(-c4cnn(CCOC5CCCCO5)c4)cc3c21 -US20100137610A1,1,CCOC(=O)c1cc2cccc(NS(=O)(=O)c3ccccc3C(F)(F)F)c2[nH]1.CI>>CCOC(=O)c1cc2cccc(N(C)S(=O)(=O)c3ccccc3C(F)(F)F)c2[nH]1 -US05646171,1,BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCCCc1nc(C(=O)OC)c(C(=O)OC)[nH]1>>CCCCc1nc(C(=O)OC)c(C(=O)OC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20020028836A1,9,Nc1cccc(F)c1.S=C(Cl)Cl>>Fc1cccc(N=C=S)c1 -US20080113966A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)nnc21>>N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)nnc21 -US07645781B2,9,COC(=O)[C@H]1CN(c2cc(F)c(N3C=CS(=O)(=O)CC3)c(F)c2)C(=O)O1.N>>NC(=O)[C@H]1CN(c2cc(F)c(N3C=CS(=O)(=O)CC3)c(F)c2)C(=O)O1 -US05959107,1,Cc1nc2cc(F)c([N+](=O)[O-])cc2s1.Sc1cccc2cnccc12>>Cc1nc2cc(Sc3cccc4cnccc34)c([N+](=O)[O-])cc2s1 -US07517888B2,9,Cn1c(-c2ccccc2)nc2c(Cl)ncnc21.N>>Cn1c(-c2ccccc2)nc2c(N)ncnc21 -US20080051418A1,1,CCOC(=O)CBr.CCOc1n[nH]cc1C(=O)NCc1ccc(Cl)cc1Cl>>CCOC(=O)Cn1cc(C(=O)NCc2ccc(Cl)cc2Cl)c(OCC)n1 -US05707997,2,CCCCc1cc(N)n2nccc2n1.COc1cc(C(=O)Cl)cc(OC)c1OC>>CCCCc1cc(NC(=O)c2cc(OC)c(OC)c(OC)c2)n2nccc2n1 -US20150274666A1,1,COc1cc(F)ccc1-c1cc(Cl)ncc1F.CSCc1cc(N)nc(F)c1>>COc1cc(F)ccc1-c1cc(Nc2cc(CSC)cc(F)n2)ncc1F -US20120202287A1,9,CCCCC[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)n1cnc2c(Cl)ncnc21.N>>CCCCC[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)n1cnc2c(N)ncnc21 -US20120015991A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.CCc1noc(-c2ccc(Br)cc2)c1NC(=O)O[C@H](C)c1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(CC)c4NC(=O)O[C@H](C)c4ccccc4)cc3)cc2)CC1 -US20110218189A1,1,CC(C)(C)OC(=O)N1CCC[C@H](Cn2c(-c3ccccc3Cl)cc3cnc(Cl)nc32)C1.NCc1ccc(F)c(F)c1>>CC(C)(C)OC(=O)N1CCC[C@H](Cn2c(-c3ccccc3Cl)cc3cnc(NCc4ccc(F)c(F)c4)nc32)C1 -US20120040954A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CC(C)N>>CC(C)NC1CCN(C(=O)OC(C)(C)C)CC1 -US20150152113A1,2,NNc1nncc(N2CCC(c3cc(F)cc(F)c3OC(F)F)CC2)c1Cl.O=C(Cl)CC(F)(F)F>>O=C(CC(F)(F)F)NNc1nncc(N2CCC(c3cc(F)cc(F)c3OC(F)F)CC2)c1Cl -US08586571B2,2,CS(=O)(=O)Cl.OCC1CN(C(c2ccccc2)c2ccccc2)C1>>CS(=O)(=O)OCC1CN(C(c2ccccc2)c2ccccc2)C1 -US08119661B2,2,CC1(N2CCC(N3C(=O)C[C@H]4CCCC[C@@H]43)CC2)CCNCC1.O=C(O)C1CC1>>CC1(N2CCC(N3C(=O)C[C@H]4CCCC[C@@H]43)CC2)CCN(C(=O)C2CC2)CC1 -US20060116383A1,7,CCOC(=O)C=C(c1ccc(CC)cc1)n1cnc2ccccc21>>CCOC(=O)CC(c1ccc(CC)cc1)n1cnc2ccccc21 -US07314937B2,1,CC(C)(C)OC(=O)N1CCc2cc(O)ccc2C1.ClCCCN1CCCCC1>>CC(C)(C)OC(=O)N1CCc2cc(OCCCN3CCCCC3)ccc2C1 -US08513239B2,2,CCOc1nc(C(C)(C)C)ncc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.OC1CCCN(C2CCNCC2)C1>>CCOc1nc(C(C)(C)C)ncc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(N2CCCC(O)C2)CC1 -US07135475B2,1,CC(C)(C)[Si](C)(C)Oc1ccccc1CBr.CCCCn1c(=O)[nH]c(=O)c2c1nc(Cc1ccc(NC(C)=O)cc1)n2COC(=O)C(C)(C)C>>CCCCn1c(=O)n(Cc2ccccc2O[Si](C)(C)C(C)(C)C)c(=O)c2c1nc(Cc1ccc(NC(C)=O)cc1)n2COC(=O)C(C)(C)C -US20110251196A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)c1ccc(OCc2ccccc2)cc1.[NH4+]>>CC(C)(C)OC(=O)N1CCC[C@@H]1C(N)c1ccc(OCc2ccccc2)cc1 -US08093239B2,2,COC(=O)c1cccc(-c2nc3ccccn3c2-c2ccnc(Nc3cccc(OCCN(C)C)c3C)n2)c1.Nc1c(F)cccc1F>>Cc1c(Nc2nccc(-c3c(-c4cccc(C(=O)Nc5c(F)cccc5F)c4)nc4ccccn34)n2)cccc1OCCN(C)C -US06326386B1,2,CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)O)c1)c1ccncc1.Fc1ccccc1NCCCn1ncnn1>>CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)N(CCCn2ncnn2)c2ccccc2F)c1)c1ccncc1 -US20090270430A1,1,CCN.CCOC(=O)c1c(C)nc(SC)nc1Cl>>CCNc1nc(SC)nc(C)c1C(=O)OCC -US04587050,1,CCOC(=O)C(=O)CCc1ccccc1.NC1CCCCCNC1=O>>CCOC(=O)C(CCc1ccccc1)NC1CCCCCNC1=O -US20140363452A1,6,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C)OC)N(C)C(=O)[C@@H](NC(=O)C(C)(C)N(C)C(=O)OCC1c2ccccc2-c2ccccc21)C(C)C>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C)OC)N(C)C(=O)[C@@H](NC(=O)C(C)(C)NC)C(C)C -US07745642B2,6,Cc1cccc(C(=O)NC(c2ccccc2)C(C)(CO[Si](C)(C)C(C)(C)C)N(C)C)c1C>>Cc1cccc(C(=O)NC(c2ccccc2)C(C)(CO)N(C)C)c1C -US20150266859A1,1,COC(=O)c1ccc(C=O)nc1.Cc1cc(N)cnc1-n1cc(C(F)(F)F)cn1>>COC(=O)c1ccc(C=Nc2cnc(-n3cc(C(F)(F)F)cn3)c(C)c2)nc1 -US20050131014A1,1,CC(C)(C)c1ccc(CBr)cc1.O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(O)c1>>CC(C)(C)c1ccc(COc2cccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1 -US07241761B2,1,C1CNCCN1.Clc1ccc2sc(Cl)nc2c1>>Clc1ccc2sc(N3CCNCC3)nc2c1 -US20140094465A1,4,CCOCCCN.O=C(O)c1ccc(C(=O)CCC(=O)c2ccc(O)cc2)cc1>>CCOCCCn1c(-c2ccc(O)cc2)ccc1-c1ccc(C(=O)O)cc1 -US20130102620A1,2,CCOC(=O)c1cnc2c(S(=O)(=O)NC3CC3)cnn2c1Nc1ccc(F)cc1C.Fc1ccc(C2CCNCC2)cc1>>Cc1cc(F)ccc1Nc1c(C(=O)N2CCC(c3ccc(F)cc3)CC2)cnc2c(S(=O)(=O)NC3CC3)cnn12 -US07803822B2,9,COC(=O)c1ccc([N+](=O)[O-])cc1CBr.[C-]#N>>COC(=O)c1ccc([N+](=O)[O-])cc1CC#N -US08440710B2,7,CC(Oc1ccc([N+](=O)[O-])cc1)C(F)(F)F>>CC(Oc1ccc(N)cc1)C(F)(F)F -US08211885B2,2,CC(C)(C)OC(=O)N1CCNCC1.COCCCOc1ccccc1-n1c(Cl)c(C(=O)O)c2ccccc21>>COCCCOc1ccccc1-n1c(Cl)c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21 -US08324216B2,1,CI.OCc1cc(Br)ccc1Cl>>COCc1cc(Br)ccc1Cl -US04017492,1,C=[N+]=[N-].O=C(O)C(CO)=NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1>>COC(=O)C(CO)=NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1 -US08829003B2,2,COc1cc(OC)c(/C=C/S(=O)(=O)Cc2ccc(OC)c(N)n2)c(OC)c1.CS(=O)(=O)Cl>>COc1cc(OC)c(/C=C/S(=O)(=O)Cc2ccc(OC)c(NS(C)(=O)=O)n2)c(OC)c1 -US20150157611A1,2,CCOC(=O)c1cn2cc(Br)ccc2n1.NCc1ccc2c(c1)OCO2>>O=C(NCc1ccc2c(c1)OCO2)c1cn2cc(Br)ccc2n1 -US20020198197A1,2,CC(C)(C)OC(=O)CC(=O)c1ccnc(C#N)c1.Cc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>Cc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2ccnc(C#N)c2)cc1C(F)(F)F -US20140135318A1,1,CCCCN(CCCC)C(=O)c1n[nH]c(C)c1Br.CCOC(=O)c1ccc(F)c(C(=O)N2CCc3ccccc3C2)c1>>CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)OCC)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Br -US07683084B2,1,Cc1cn(-c2ccc3c(c2)OC(F)(F)C(F)(F)O3)c(=N)s1.O=C(Cl)C1CCC1>>Cc1cn(-c2ccc3c(c2)OC(F)(F)C(F)(F)O3)/c(=N/C(=O)C2CCC2)s1 -US05185337,1,CN1CCNCC1.C[C@@H]1Cc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23>>C[C@@H]1Cc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 -US06071901,1,COC(=O)C1CCCNC1C.ClCCCN1c2ccccc2CCc2ccccc21>>COC(=O)C1CCCN(CCCN2c3ccccc3CCc3ccccc32)C1C -US08003783B2,3,C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O.O=Cc1ccc([N+](=O)[O-])cc1>>CC12CCC3c4ccc(O)cc4CCC3C1CC(=Cc1ccc([N+](=O)[O-])cc1)C2=O -US20060025432A1,1,BrCc1ccccc1.Oc1cc(O)nc(S)n1>>Oc1cc(O)nc(SCc2ccccc2)n1 -US20130079303A1,1,Cc1nc(N)nc(-c2cccnc2F)n1.Nc1ccc(N)nc1>>Cc1nc(N)nc(-c2cccnc2Nc2ccc(N)nc2)n1 -US08552039B2,6,COC(=O)CCCCc1noc(-c2ccccc2OC)n1>>COc1ccccc1-c1nc(CCCCC(=O)O)no1 -US20060276518A1,2,COC(=O)[C@@H](N)Cc1ccc(O)cc1.O=C(O)c1cc2ccccc2cn1>>COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cc2ccccc2cn1 -US20070093483A1,1,CCCCBr.O=C(O)COc1ccccc1O>>CCCCOc1ccccc1OCC(=O)O -US20120295897A1,1,IC[C@@H]1COCCO1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCCO3>>O=C1N(C[C@@H]2COCCO2)c2ccccc2C12COc1cc3c(cc12)OCCCO3 -US07157463B2,1,COC(=O)C(Cc1ccc(Cl)cc1)NCC1Cc2ccccc2CN1C(=O)OC(C)(C)C.COCC=O>>COCCN(CC1Cc2ccccc2CN1C(=O)OC(C)(C)C)C(Cc1ccc(Cl)cc1)C(=O)OC -US07368578B2,8,Cc1oc(-c2ccccc2)nc1COc1cccc(COc2nn(Cc3ccccc3)cc2CO)c1>>Cc1oc(-c2ccccc2)nc1COc1cccc(COc2nn(Cc3ccccc3)cc2C=O)c1 -US20150246922A1,3,N#Cc1cc(Br)c2c(c1)cc1n2CCNC1=O.OB(O)c1cccc(F)c1>>N#Cc1cc(-c2cccc(F)c2)c2c(c1)cc1n2CCNC1=O -US04699905,6,CCOC(=O)C(CCc1ccccc1)NC1CSC(c2cccs2)CN(CC(=O)OC(C)(C)C)C1=O>>CCOC(=O)C(CCc1ccccc1)NC1CSC(c2cccs2)CN(CC(=O)O)C1=O -US08258134B2,1,COC(=O)C(Br)CC1CCCC1.O=c1cc(Cc2ccccc2C(F)(F)F)cn[nH]1>>COC(=O)C(CC1CCCC1)n1ncc(Cc2ccccc2C(F)(F)F)cc1=O -US20130053382A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1(c2ccc(Br)cc2)CC1>>CC(C)(C)OC(=O)NC1(c2ccc(Br)cc2)CC1 -US20030229949A1,1,C1CCNC1.CS(=O)(=O)OC1CCN(c2ccc([N+](=O)[O-])cc2)C1>>O=[N+]([O-])c1ccc(N2CCC(N3CCCC3)C2)cc1 -US20110021518A1,7,Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1F>>Nc1ccc(Oc2ccccc2)c(F)c1N -US07807685B2,3,Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.OB(O)c1cc(F)cc(F)c1>>Nc1nc(-c2cc(F)cc(F)c2)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O -US20060100240A1,6,CC(C)(C)OC(=O)n1c(CN(CCn2ccnc2)C2CCCc3cccnc32)nc2ccccc21>>c1cnc2c(c1)CCCC2N(CCn1ccnc1)Cc1nc2ccccc2[nH]1 -US20090076074A1,2,CCn1cc(N)c(C)n1.COc1cc(OCc2ccccc2)ccc1CC(=O)O>>CCn1cc(NC(=O)Cc2ccc(OCc3ccccc3)cc2OC)c(C)n1 -US04757080,6,COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2C(=O)c3ccccc3C2=O)C1c1cccc(Cl)c1Cl>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN)C1c1cccc(Cl)c1Cl -US05286728,1,CCI.O=C(CS)Nc1ccc(C(=O)O)cc1>>CCSCC(=O)Nc1ccc(C(=O)O)cc1 -US20110212966A1,6,COc1ccc2nncc(Cl)c2c1>>Oc1ccc2nncc(Cl)c2c1 -US20120108422A1,4,CC(CC(=O)C(C)(C)C)Cc1ccccc1Cl.C[S+](C)C>>CC(Cc1ccccc1Cl)CC1(C(C)(C)C)CO1 -US04798620,6,CCOC(=O)CN1C(=O)COc2cc(F)c([N+](=O)[O-])cc21>>O=C(O)CN1C(=O)COc2cc(F)c([N+](=O)[O-])cc21 -US20100160323A1,2,NCC(=O)N1CCN(C(=O)c2cc(F)c(F)c(F)c2)CC1.O=C(O)c1cn(C2CCCC2)nn1>>O=C(NCC(=O)N1CCN(C(=O)c2cc(F)c(F)c(F)c2)CC1)c1cn(C2CCCC2)nn1 -US08507491B2,3,Cc1ccc(N)cc1B1OC(C)(C)C(C)(C)O1.Clc1cc2ccccc2cn1>>Cc1ccc(N)cc1-c1cc2ccccc2cn1 -US05859063,6,CC(=O)OCC(=O)C(C)(C)NC(=O)c1cc(Cl)cc(Cl)c1>>CC(C)(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)CO -US20050038035A1,2,Cc1ccc(C(=O)Nc2ccc(N)cc2)c(-c2ccc(C(F)(F)F)cc2)c1.O=C(O)Cc1ccccn1>>Cc1ccc(C(=O)Nc2ccc(NC(=O)Cc3ccccn3)cc2)c(-c2ccc(C(F)(F)F)cc2)c1 -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CN(C(=O)C2(F)CCNCC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.COC(=O)Cl>>COC(=O)N1CCC(F)(C(=O)N2C[C@@H](c3ccc(F)cc3)[C@H](N(C)C(=O)N(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2)CC1 -US05599951,2,CC(=O)Cl.O=C(O)C(O)Cc1ccccc1>>CC(=O)OC(Cc1ccccc1)C(=O)O -US20150246912A1,6,CCOC(=O)Cn1nc(C(C)C)cc1C>>Cc1cc(C(C)C)nn1CC(=O)O -US20100249124A1,3,CC(c1ccc(Br)cc1Cl)C(O)(c1ccc(=O)n2ccccc12)C(F)(F)F.COC(=O)c1ccc(B(O)O)cc1F>>COC(=O)c1ccc(-c2ccc(C(C)C(O)(c3ccc(=O)n4ccccc34)C(F)(F)F)c(Cl)c2)cc1F -US04673746,9,COc1ccc(C(=O)c2ccccc2F)c(O)c1Cl.NO>>COc1ccc(/C(=N\O)c2ccccc2F)c(O)c1Cl -US05693635,2,Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1.O=C(Cl)c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1)c1ccc(C(F)(F)F)cc1 -US20040138230A1,1,CC1(C)Cc2cc(CCCCl)ccc2NC1=O.c1ccc2c(N3CCNCC3)nsc2c1>>CC1(C)Cc2cc(CCCN3CCN(c4nsc5ccccc45)CC3)ccc2NC1=O -US20080200471A1,6,CC(=O)n1ncc2ccc(Br)cc21>>Brc1ccc2cn[nH]c2c1 -US05700940,1,CC[O-].Fc1ncc(Cl)c(F)c1Cl>>CCOc1c(Cl)cnc(F)c1Cl -US20070293477A1,6,CC(C)C[C@H](NC(=O)c1cc2ccccc2n1C)C(=O)NC1CCCN(C(=O)OC(C)(C)C)CC1>>CC(C)C[C@H](NC(=O)c1cc2ccccc2n1C)C(=O)NC1CCCNCC1 -US08461330B2,1,CC(C)(C)OC(=O)NC1CCNC1.Fc1ccccn1>>CC(C)(C)OC(=O)NC1CCN(c2ccccn2)C1 -US04328367,8,CCSCCNC(=O)C1=C(C(=O)Nc2ccc(Cl)cc2F)CCCC1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)CCNC(=O)C1=C(C(=O)Nc2ccc(Cl)cc2F)CCCC1 -US07354934B2,6,O=C1c2ccccc2C(=O)N1CCCCN(Cc1nc2c(F)cccc2[nH]1)C1CCCc2cccnc21>>NCCCCN(Cc1nc2c(F)cccc2[nH]1)C1CCCc2cccnc21 -US20130040988A1,2,N#Cc1ccc(S(=O)(=O)Cl)cc1.Nc1cnc(Oc2cc3ccccc3cn2)c(Cl)c1>>N#Cc1ccc(S(=O)(=O)Nc2cnc(Oc3cc4ccccc4cn3)c(Cl)c2)cc1 -US20130131059A1,1,CC(C)(C)C(=O)OCCOc1cccc(C=O)c1.c1cc(N[C@@H]2CCNC2)c2ccncc2c1>>CC(C)(C)C(=O)OCCOc1cccc(CN2CC[C@@H](Nc3cccc4cnccc34)C2)c1 -US20100113435A1,2,CCNC.Nc1nc(CC(=O)O)cs1>>CCN(C)C(=O)Cc1csc(N)n1 -US07820658B2,7,CCOC(=O)c1cc2c(C=Cc3ccccc3)nc(N)nc2s1>>CCOC(=O)c1cc2c(CCc3ccccc3)nc(N)nc2s1 -US20060030609A1,7,O=C1Cc2cc([N+](=O)[O-])ccc2N1CCF>>Nc1ccc2c(c1)CC(=O)N2CCF -US20120149721A1,2,CC(=O)Cl.COc1cc(-c2ncnc3c(C(=O)N[C@@H]4CC[C@@H](N)CC4)c(C)[nH]c23)c(OCC2CC2)cc1F>>COc1cc(-c2ncnc3c(C(=O)N[C@@H]4CC[C@@H](NC(C)=O)CC4)c(C)[nH]c23)c(OCC2CC2)cc1F -US20060160864A1,1,C1=CCNC1.O=Cc1cc(Br)ccc1F>>O=Cc1cc(Br)ccc1N1CC=CC1 -US04324790,1,ClCC1CC1.O=[N+]([O-])c1ccc2[nH]cc(C3=CCNCC3)c2c1>>O=[N+]([O-])c1ccc2[nH]cc(C3=CCN(CC4CC4)CC3)c2c1 -US20140371276A1,1,CC(N)=O.CCOC(=O)c1sc(-c2ccc(C)cc2)nc1OS(=O)(=O)C(F)(F)F>>CCOC(=O)c1sc(-c2ccc(C)cc2)nc1NC(C)=O -US20090163471A1,9,COC(=O)c1cc(N)c(C#N)cc1C.ICI>>COC(=O)c1cc(I)c(C#N)cc1C -US07781430B2,2,CC(=O)OC(C)=O.Nc1ccc(-c2nc3c(C(=O)NC4CN5CCC4CC5)cccc3o2)cc1>>CC(=O)Nc1ccc(-c2nc3c(C(=O)NC4CN5CCC4CC5)cccc3o2)cc1 -US20070049582A1,1,COc1cc2nc[nH]c(=O)c2cc1OC.ClCCCI>>COc1cc2ncn(CCCCl)c(=O)c2cc1OC -US20080306046A1,4,CNc1ccccc1N.O=C(O)CCCC1CCNCC1>>Cn1c(CCCC2CCNCC2)nc2ccccc21 -US20050215584A1,7,CCOC(=O)c1cc2ccccc2[nH]1>>OCc1cc2ccccc2[nH]1 -US08440830B2,6,CC(=O)Nc1ccc(Br)cc1[N+](=O)[O-]>>Nc1ccc(Br)cc1[N+](=O)[O-] -US20070213325A1,6,COc1ccc(Nc2nn(-c3ccccc3)cc2C)cc1>>Cc1cn(-c2ccccc2)nc1Nc1ccc(O)cc1 -US08933225B2,4,CC(C)(C)OO.OCC1=CC[C@H](NC(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>OC[C@@]12C[C@@H](NC(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@@H]1O2 -US20140213616A1,2,COc1cc(N)ccn1.O=C(Cl)c1cc(C(F)(F)F)ccc1F>>COc1cc(NC(=O)c2cc(C(F)(F)F)ccc2F)ccn1 -US03985885,7,O=[N+]([O-])c1ccc2sc(-c3cccnc3)nc2c1>>Nc1ccc2sc(-c3cccnc3)nc2c1 -US06982348B2,7,COC(=O)c1ccc(C(C)(F)F)cc1>>CC(F)(F)c1ccc(CO)cc1 -US20110092612A1,2,C=CC(=O)Cl.Oc1ccc(-c2cccc3c2sc2ccccc23)cc1-c1cccc2c1sc1ccccc12>>C=CC(=O)Oc1ccc(-c2cccc3c2sc2ccccc23)cc1-c1cccc2c1sc1ccccc12 -US20150126517A1,6,COc1ccc2c(c1)CN(S(=O)(=O)c1ccccc1[N+](=O)[O-])CC2c1ccc(Cl)c(Cl)c1>>O=[N+]([O-])c1ccccc1S(=O)(=O)N1Cc2cc(O)ccc2C(c2ccc(Cl)c(Cl)c2)C1 -US20150105373A1,9,COCC(=O)c1ccc(OC(F)(F)F)c(F)c1.NO>>COCC(=NO)c1ccc(OC(F)(F)F)c(F)c1 -US20100130538A1,3,Cn1cc2c(/C=C\CO)cccc2n1.ICI>>Cn1cc2c([C@H]3C[C@H]3CO)cccc2n1 -US06566362B2,1,CC1(C)CCCNC1.CCOC(=O)c1cn(C)c2cnc3cc(F)c(F)cc3c2c1=O>>CCOC(=O)c1cn(C)c2cnc3cc(N4CCCC(C)(C)C4)c(F)cc3c2c1=O -US20130274469A1,7,CCOC(=O)c1c(-c2ccc(Cl)cc2)noc1C>>Cc1onc(-c2ccc(Cl)cc2)c1CO -US08324216B2,1,CCOC(=O)CBr.Cc1[nH]nc(-c2cccnc2)c1Cl>>CCOC(=O)Cn1nc(-c2cccnc2)c(Cl)c1C -US04497738,8,O=C(COc1ccccc1)NC1C(=O)N2C1SCN(S(=O)(=O)C(F)(F)F)C2C(=O)OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>O=C(COc1ccccc1)NC1C(=O)N2C(C(=O)OCc3ccccc3)N(S(=O)(=O)C(F)(F)F)CS(=O)C12 -US07396840B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCCc1nc2ccccc2[nH]1>>CC(C)(C)OC(=O)n1c(CCCO)nc2ccccc21 -US20140094462A1,3,C=CCCC(=O)N[C@@H](COC(=O)[C@@H](CC=C)NC(=O)OC(C)(C)C)c1ccc(F)cc1>>CC(C)(C)OC(=O)N[C@@H]1CC=CCCC(=O)N[C@H](c2ccc(F)cc2)COC1=O -US20040039200A1,7,Clc1ccc2cc3n(c2c1)CCNC3>>Clc1ccc2c(c1)N1CCNCC1C2 -US07470715B2,3,CC(C)(C)[Si](C)(C)Oc1ccc(-c2noc(C3(C=O)CC3)c2-c2ccccc2)cc1.CC[Mg+]>>CCC(O)C1(c2onc(-c3ccc(O[Si](C)(C)C(C)(C)C)cc3)c2-c2ccccc2)CC1 -US09132126B2,2,COc1cccc(N2CCNCC2)c1.Cc1onc(-c2ccccc2Cl)c1C(=O)O>>COc1cccc(N2CCN(C(=O)c3c(-c4ccccc4Cl)noc3C)CC2)c1 -US20090137580A1,1,COS(C)(=O)=O.Clc1ncnc2cc[nH]c12>>Cn1ccc2ncnc(Cl)c21 -US20100029628A1,2,COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)[C@@H](C(=O)O)C[C@@H]3c3ccc(OC)cc3)cc21.NCc1cccc(-c2ccccc2)c1>>COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)[C@@H](C(=O)NCc4cccc(-c5ccccc5)c4)C[C@@H]3c3ccc(OC)cc3)cc21 -US20080132504A1,1,Clc1ncc(Br)c(Cl)n1.Nc1ccccc1S(N)(=O)=O>>NS(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Br -US04927968,6,O=C1c2ccccc2C(=O)N1CCCOc1cccc(C2OCCO2)c1>>NCCCOc1cccc(C2OCCO2)c1 -US05834506,6,CC(C)C1(CCc2ccc(OCc3ccccc3)cc2)CC(O)=CC(=O)O1>>CC(C)C1(CCc2ccc(O)cc2)CC(O)=CC(=O)O1 -US20050124605A1,2,COc1cc(CC(=O)Cl)cc(OC)c1.COc1cc(OC)cc(O[C@H](C(=O)O)[C@@]2(c3ccccc3)NCCc3ccccc32)c1>>COc1cc(CC(=O)N2CCc3ccccc3[C@@]2(c2ccccc2)[C@H](Oc2cc(OC)cc(OC)c2)C(=O)O)cc(OC)c1 -US08455477B2,3,C#CC1CN(C(=O)OCc2cccnc2)C1.COc1cc(-c2cnn(C)c2)cn2ncc(I)c12>>COc1cc(-c2cnn(C)c2)cn2ncc(C#CC3CN(C(=O)OCc4cccnc4)C3)c12 -US20120270865A2,1,COC(=O)c1oc2ccc(F)cc2c1CBr.C[O-]>>COCc1c(C(=O)OC)oc2ccc(F)cc12 -US20150141372A1,1,Brc1ccncc1.COCC(=O)Nc1nc(-c2nn(Cc3ccccc3F)c3c2CCC3)nc(N)c1OC>>COCC(=O)Nc1nc(-c2nn(Cc3ccccc3F)c3c2CCC3)nc(Nc2ccncc2)c1OC -US08420810B2,1,CCC(CC)c1cc(C)n2nc(-c3ccc(OC)cc3Cl)[nH]c(=O)c12.COC(=O)CBr>>CCC(CC)c1cc(C)n2nc(-c3ccc(OC)cc3Cl)n(CC(=O)OC)c(=O)c12 -US08461387B2,1,CC(C)(C)CC(C)(C)N.CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O>>CC(C)(C)CC(C)(C)N=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 -US20110039821A1,2,CN(C)C(=O)c1ccc(Oc2cc(C(=O)OC(C)(C)C)cc3c2CC(C)(CO)O3)cc1F.Cc1ccc(N)nc1>>Cc1ccc(NC(=O)c2cc(Oc3ccc(C(=O)N(C)C)c(F)c3)c3c(c2)OC(C)(CO)C3)nc1 -US20120316147A1,2,CC(C)(N)c1ccccn1.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>CC(C)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)c1ccccn1 -US07977362B2,1,Fc1c(CBr)ccc(-c2ncco2)c1F.O=S(=O)(N[C@@H]1CCCC[C@H]1CO)c1ccc(Cl)cc1>>O=S(=O)(c1ccc(Cl)cc1)N(Cc1ccc(-c2ncco2)c(F)c1F)[C@@H]1CCCC[C@H]1CO -US20100280268A1,2,CCc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1N.Cc1ccc(S(=O)(=O)Cl)cc1>>CCc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1 -US20090005415A1,2,CC(C)CCS(=O)(=O)Cl.Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1>>Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(C)C)cc1 -US20110275797A1,6,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(N2CCOCC2)ccc1O>>O=C(Nc1cc(-c2ccccc2)ccc1C(=O)O)c1cc(N2CCOCC2)ccc1O -US20050245593A1,2,CN(C)C1(c2ccccc2)CCC(CN)CC1.O=C(O)CCn1ccc2ccccc21>>CN(C)C1(c2ccccc2)CCC(CNC(=O)CCn2ccc3ccccc32)CC1 -US08735410B2,6,CNC(=O)[C@H]1C[C@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CCN1C(=O)OC(C)(C)C>>CNC(=O)[C@H]1C[C@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CCN1 -US20080039440A1,9,[N-]=[N+]=Nc1cc(Oc2ccc3c(c2)CCN3C(=O)Nc2cccc(C(F)(F)F)c2)ncn1>>Nc1cc(Oc2ccc3c(c2)CCN3C(=O)Nc2cccc(C(F)(F)F)c2)ncn1 -US20090221555A1,1,COc1c(N)ccc2c1CCC(NCCO)CC2.O=S(=O)(c1ccccc1Nc1nc(Cl)ncc1Cl)N1CCC(O)C1>>COc1c(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)N3CCC(O)C3)n2)ccc2c1CCC(NCCO)CC2 -US20070099909A1,1,CCCOc1cccc(C=O)c1.COc1ccc2[nH]cc(CCN)c2c1>>CCCOc1cccc(CNCCc2c[nH]c3ccc(OC)cc23)c1 -US20120220013A1,9,CC(C)(C)OC(=O)NCCOCCOc1ccc(CCO)cc1.ClC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)NCCOCCOc1ccc(CCCl)cc1 -US04054719,1,CCCC(=O)O.O=C(CBr)c1ccc(-c2ccccc2)cc1>>CCCC(=O)OCC(=O)c1ccc(-c2ccccc2)cc1 -US20080176857A1,1,CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(Cl)nc2s1.COC(=O)CS>>CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(SCC(=O)OC)nc2s1 -US07504410B2,7,O=C1CNC(=O)N1c1cccc([N+](=O)[O-])c1>>Nc1cccc(N2C(=O)CNC2=O)c1 -US04575503,7,CC(C)(C)OC(=O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CC(=O)c2ccccc21>>CC(C)(C)OC(=O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CC(O)c2ccccc21 -US04649160,1,O=C(O)CCl.OCCc1ccc(Cl)cc1>>O=C(O)COCCc1ccc(Cl)cc1 -US20150225396A1,1,O=C(O)CCBr.O=c1[nH]c(S)nc2ccc(F)cc12>>O=C(O)CCSc1nc2ccc(F)cc2c(=O)[nH]1 -US20120178736A1,1,COC(C)c1nc2ccccc2[nH]1.Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(Cl)nc21>>CO[C@@H](C)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1 -US07169815B2,2,CCCCCCCCN.COc1cccc(CN=C=S)c1>>CCCCCCCCNC(=S)NCc1cccc(OC)c1 -US08552208B2,1,CC[C@H](C)[C@H](N)C(=O)OC.O=Cc1ccccc1>>CC[C@H](C)[C@H](NCc1ccccc1)C(=O)OC -US20070249670A1,6,COC(=O)C1(NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(Cl)cccc2Cl)CCOCC1>>O=C(Nc1cc2ccccc2cc1C(=O)NC1(C(=O)O)CCOCC1)Nc1c(Cl)cccc1Cl -US04818754,2,CCCCC(=O)Cl.Cc1cc(NCCO)c2nn(C)cc2n1>>CCCCC(=O)OCCNc1cc(C)nc2cn(C)nc12 -US20100324052A1,2,CC(C)(C)[SiH2]OC(C)(C)c1cc(CCN)ccc1Cl.O=C(O)CC(F)(F)F>>CC(C)(C)[SiH2]OC(C)(C)c1cc(CCNC(=O)CC(F)(F)F)ccc1Cl -US08748426B2,2,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O.O=C=Nc1c(F)cccc1F>>COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)Nc4c(F)cccc4F)cc3)cc2C1=O -US20140179689A1,1,CC(=O)Nc1cccc(CNC(=O)c2cccc3[nH]ccc23)c1.Nc1nccc(Cl)n1>>CC(=O)Nc1cccc(CNC(=O)c2cccc3c2ccn3-c2ccnc(N)n2)c1 -US05236931,2,NC1CN2CCC1CC2.Nc1cc(OCc2ccccc2)c(C(=O)O)cc1Cl>>Nc1cc(OCc2ccccc2)c(C(=O)NC2CN3CCC2CC3)cc1Cl -US20090275570A1,3,C#Cc1ccccc1.CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3sc(I)cc23)C1>>CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3sc(C#Cc4ccccc4)cc23)C1 -US20150038590A1,1,CC(=O)c1cc(F)ccc1C1=CCCC1.NC1CC1>>CC(NC1CC1)c1cc(F)ccc1C1=CCCC1 -US05968930,7,COc1cc(C(=O)N2Cc3cccn3Cc3ccccc32)ccc1[N+](=O)[O-]>>COc1cc(C(=O)N2Cc3cccn3Cc3ccccc32)ccc1N -US20080312192A1,7,CN1CCC(Oc2ccc([N+](=O)[O-])cc2C(F)(F)F)CC1>>CN1CCC(Oc2ccc(N)cc2C(F)(F)F)CC1 -US07192943B2,1,BrCCNC(c1ccccc1)(c1ccccc1)c1ccccc1.CC(C)(C)OC(=O)NCCN>>CC(C)(C)OC(=O)NCCNCCNC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20080045546A1,1,Nc1cccc2cc(O)ccc12.O=Cc1ccccc1>>Oc1ccc2c(N=Cc3ccccc3)cccc2c1 -US20050070582A1,1,CC(C)(C)OC(=O)N1CCCN(S(=O)(=O)c2cc(C#N)ccc2F)CC1.Oc1cc(Cl)cc(Cl)c1>>CC(C)(C)OC(=O)N1CCCN(S(=O)(=O)c2cc(C#N)ccc2Oc2cc(Cl)cc(Cl)c2)CC1 -US08394799B2,2,Nc1ccc(Cl)cc1.O=C(COc1ccc(C23CC4CC(CC(C4)C2)C3)cc1)Nc1cc(C(=O)O)ccn1>>O=C(COc1ccc(C23CC4CC(CC(C4)C2)C3)cc1)Nc1cc(C(=O)Nc2ccc(Cl)cc2)ccn1 -US06444812B1,2,CNOC.Nc1c(C(=O)O)cc(Br)cc1[N+](=O)[O-]>>CON(C)C(=O)c1cc(Br)cc([N+](=O)[O-])c1N -US06974802B2,1,C=CCC(C)(C)C(=O)O.COc1ccc(CCl)cc1>>C=CCC(C)(C)C(=O)OCc1ccc(OC)cc1 -US20130045942A1,9,CC(=O)c1ccc(N)cc1.NO>>CC(=NO)c1ccc(N)cc1 -US20040110754A1,1,CN(C)[C@@H]1CCNC1.C[C@H](NC(=O)OC(C)(C)C)c1cccc(Br)c1>>CC(NC(=O)OC(C)(C)C)c1cccc(N2CCC(N(C)C)C2)c1 -US04892961,8,CC(CO)COC1CCCCO1>>CC(C=O)COC1CCCCO1 -US20120302547A1,3,CB(O)O.O=C1OCCc2c(I)csc21>>Cc1csc2c1CCOC2=O -US20050032830A1,1,Cc1nc(Oc2ccccc2)c2nc(C)n(CCCCCCl)c2c1C.Sc1ccccc1>>Cc1nc(Oc2ccccc2)c2nc(C)n(CCCCCSc3ccccc3)c2c1C -US20100120775A1,7,CCOC(=O)c1c(-c2c(Cl)cccc2Cl)noc1C1CCC1>>OCc1c(-c2c(Cl)cccc2Cl)noc1C1CCC1 -US20080114007A1,6,CCOC(=O)c1cn(-c2ccc(CC)cc2)c2nc(SC)ncc2c1=O>>CCc1ccc(-n2cc(C(=O)O)c(=O)c3cnc(SC)nc32)cc1 -US04631343,2,CCOC(=O)c1cnn(-c2ccc(Br)cc2)c1C#N.CN>>CNC(=O)c1cnn(-c2ccc(Br)cc2)c1C#N -US20150239900A1,1,Clc1ccc(-c2cc3c(Cl)ncnc3cc2Cl)cc1.NC(=O)C1CNCCN1>>NC(=O)C1CN(c2ncnc3cc(Cl)c(-c4ccc(Cl)cc4)cc23)CCN1 -US06515013B2,8,N#Cc1ccc(-c2ccc(OCCCN3CC[C@@H](O)C3)cc2)cc1>>N#Cc1ccc(-c2ccc(OCCCN3CCC(=O)C3)cc2)cc1 -US04051253,1,CCCCc1ccccc1C(=O)NN.O=CC=Cc1ccc([N+](=O)[O-])o1>>CCCCc1ccccc1C(=O)NN=CC=Cc1ccc([N+](=O)[O-])o1 -US20030027743A1,2,CCCCN.O=C(O)[C@@H]1Cc2ccccc2N1C(=O)OCc1ccccc1>>CCCCNC(=O)[C@@H]1Cc2ccccc2N1C(=O)OCc1ccccc1 -US20150152092A1,6,CCc1cnn(C)c1-c1cc(C(=O)OC)sc1C>>CCc1cnn(C)c1-c1cc(C(=O)O)sc1C -US05229388,1,Fc1ccc(N2CCNCC2)cc1.O=C1CSCN1CCCCBr>>O=C1CSCN1CCCCN1CCN(c2ccc(F)cc2)CC1 -US20100016287A1,1,CCc1nc2cc3c(cc2o1)CCNCC3.Cc1ccc2c(-c3nnc(SCCCCl)n3C)cccc2n1>>CCc1nc2cc3c(cc2o1)CCN(CCCSc1nnc(-c2cccc4nc(C)ccc24)n1C)CC3 -US08198302B2,3,COc1cc(Br)cc(C=O)c1OC.OB(O)c1ccccc1>>COc1cc(-c2ccccc2)cc(C=O)c1OC -US20120184561A1,7,COC(=O)Cc1ccc(Nc2ncccc2[N+](=O)[O-])cc1C>>COC(=O)Cc1ccc(Nc2ncccc2N)cc1C -US20030181499A1,3,CC(=O)OC(C)=O.CC(C)(C)C(=O)n1ccc2ccc(OC(=O)CCl)cc21>>CC(=O)c1cn(C(=O)C(C)(C)C)c2cc(OC(=O)CCl)ccc12 -US20090075980A1,9,CCCCn1nc(C(=O)OCC)cc1CC.[NH4+]>>CCCCn1nc(C(N)=O)cc1CC -US07569601B2,3,C#CCCO.CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(I)cc2)CC(C)(C)C1>>CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(C#CCCO)cc2)CC(C)(C)C1 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.O=Cc1cccn1-c1ccc(Cl)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(Cc3cccn3-c3ccc(Cl)cc3)CC2)c1 -US20140004243A1,2,CC(C)(C)OC(=O)NCC(=O)O.Nc1cccc(CNC(=S)NCCc2ccccc2)c1>>CC(C)(C)OC(=O)NCC(=O)Nc1cccc(CNC(=S)NCCc2ccccc2)c1 -US20060183762A1,6,CC(C)(C)OC(=O)N[C@H]1CCN(c2c(F)c(NCc3ccccc3)c3c(=O)n(NC(=O)OC(C)(C)C)c(=O)n(C4CC4)c3c2F)C1>>CC(C)(C)OC(=O)N[C@H]1CCN(c2c(F)c(N)c3c(=O)n(NC(=O)OC(C)(C)C)c(=O)n(C4CC4)c3c2F)C1 -US20150259341A1,3,CC1(C)OB(c2ccnn2-c2ccc(C(F)(F)F)cc2)OC1(C)C.N#Cc1ccc(-c2cnc3ccc(Br)cn23)cc1>>N#Cc1ccc(-c2cnc3ccc(-c4ccnn4-c4ccc(C(F)(F)F)cc4)cn23)cc1 -US20090042896A1,2,O=C(O)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C1OC[C@H](Cc2ccccc2)N1C(=O)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)c(Cl)c1 -US20070123573A1,6,Nc1nc2c(s1)CC(N1C(=O)c3ccccc3C1=O)CC2>>Nc1nc2c(s1)CC(N)CC2 -US07674804B2,1,CCOc1cc(CN2CCC(N)CC2)ccc1OC.Cc1cc(Cl)nc(N)n1>>CCOc1cc(CN2CCC(Nc3cc(C)nc(N)n3)CC2)ccc1OC -US04010177,1,C1CCNC1.ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>Clc1ccc2c(c1)C(c1ccccc1)=NCc1nnc(CN3CCCC3)n1-2 -US05447943,7,CC1C(=O)c2cc([N+](=O)[O-])ccc2OC1(C)C>>CC1C(O)c2cc([N+](=O)[O-])ccc2OC1(C)C -US08299267B2,6,COC(=O)c1cccc(C(=O)OC)c1OC>>COC(=O)c1cccc(C(=O)OC)c1O -US05770615,6,COc1ccc([C@](C)(NC(C)=O)C(=O)O)cc1>>COc1ccc([C@](C)(N)C(=O)O)cc1 -US20060052365A1,2,O=C(N[C@@H](CC1CCCC1)C(=O)NC1CCCNCC1O)c1ccco1.O=C(O)c1ccco1>>O=C(N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)c2ccco2)CC1O)c1ccco1 -US20150166480A1,6,CCOC(=O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)cc1F>>O=C(O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)cc1F -US20140163206A1,1,COc1ccc(CCl)cc1.Nc1ccc(Br)c(Cl)c1Cl>>COc1ccc(CNc2ccc(Br)c(Cl)c2Cl)cc1 -US06593322B1,2,Nc1ccc(F)cc1.O=C(O)Cc1cccc(O)c1>>O=C(Cc1cccc(O)c1)Nc1ccc(F)cc1 -US05519034,4,COc1ccc(CCNC(=O)C2CCC2)cc1OC>>COc1cc2c(cc1OC)C(C1CCC1)=NCC2 -US20150265617A1,3,CC1(C)OB(C2=CCOCC2)OC1(C)C.Clc1c(-c2ccccc2)nnc2c1c(I)nn2CCN1CCCC1>>Clc1c(-c2ccccc2)nnc2c1c(C1=CCOCC1)nn2CCN1CCCC1 -US20110144105A1,7,CCOC(=O)C=C1CCOCC1>>CCOC(=O)CC1CCOCC1 -US07625948B2,6,CC(C)(C)[Si](C)(C)OCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21>>O=C(NCC(F)(F)F)C1(CCO)c2ccccc2-c2ccccc21 -US05059621,1,CCCCCCCCCC(C)(C)c1cc(Br)ccc1O.CI>>CCCCCCCCCC(C)(C)c1cc(Br)ccc1OC -US20130096135A1,6,CC(C)(C)OC(=O)NC1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)CC1>>NC1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)CC1 -US20050197511A1,6,CO[C@H](CNC(=O)OCc1ccccc1)c1ccc(OC(C)=O)cc1>>CO[C@H](CNC(=O)OCc1ccccc1)c1ccc(O)cc1 -US20150119392A1,3,CC(C)(C)CCNC(=O)Nc1cc(B2OC(C)(C)C(C)(C)O2)c(F)cc1F.CNc1ncc2cc(Br)c(C)nc2n1>>CNc1ncc2cc(-c3cc(NC(=O)NCCC(C)(C)C)c(F)cc3F)c(C)nc2n1 -US08044069B2,2,Clc1ccc(OC2CCNCC2)cc1.O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCCC(c2ccccc2)(c2ccccc2)C1=O)N1CCC(Oc2ccc(Cl)cc2)CC1 -US20140066455A1,6,COC(=O)c1cnc(C2CCN(C(=O)OC(C)(C)C)CC2)nc1>>COC(=O)c1cnc(C2CCNCC2)nc1 -US20070197488A1,6,C=C[C@@]12CCc3cc(O[Si](C)(C)C(C)(C)C)ccc3[C@H]1CC[C@@]1(C)[C@H]2CC[C@@H]1O[Si](C)(C)C(C)(C)C>>C=C[C@@]12CCc3cc(O[Si](C)(C)C(C)(C)C)ccc3[C@H]1CC[C@@]1(C)[C@H]2CC[C@@H]1O -US08217177B2,3,C#C[Si](CC)(CC)CC.COc1cnc2c(NCc3nnc4ccc(Cl)nn34)ccnc2c1>>CC[Si](C#Cc1ccc2nnc(CNc3ccnc4cc(OC)cnc34)n2n1)(CC)CC -US06110946,2,CCOC(=O)N[C@H](C(=O)O)C(C)C.COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(N)Cc1ccc(-c2cncs2)cc1)C(C)C>>CCOC(=O)N[C@H](C(=O)NN(Cc1ccc(-c2cncs2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OC)C(C)C)C(C)C -US20140128385A1,9,CCOC(=O)[C@@](C)(OCC(C)(NC(=O)OC(C)(C)C)c1cccc(Br)n1)C(F)(F)F.N>>CC(C)(C)OC(=O)NC(C)(CO[C@](C)(C(N)=O)C(F)(F)F)c1cccc(Br)n1 -US07312214B2,2,COC(=O)C(C)(C)c1ccc(C(=O)Cl)cc1.Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1>>COC(=O)C(C)(C)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 -US20120245148A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(N3CCN(CCS(C)(=O)=O)CC3)cn2)c2ccccc21>>CS(=O)(=O)CCN1CCN(c2ccc(N3CCNc4ccccc43)nc2)CC1 -US07482355B2,1,C=CCO.C[C@H](CO[Si](C)(C)C(C)(C)C)Nc1nc(SCc2cccc(F)c2F)nc(Cl)c1C=O>>C=CCOc1nc(SCc2cccc(F)c2F)nc(N[C@H](C)CO[Si](C)(C)C(C)(C)C)c1C=O -US20030149035A1,3,C#Cc1cccnc1.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)cc(I)c21>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)cc(C#Cc3cccnc3)c21 -US03987047,6,CCOC(=O)CCN1CCc2nc3ccccc3c(C)c2CC1>>Cc1c2c(nc3ccccc13)CCN(CCC(=O)O)CC2 -US04147700,2,C#CCOCc1nnc(CN)n1-c1ccc(Cl)cc1C(=O)c1ccccc1.O=C(Cl)CN1C(=O)c2ccccc2C1=O>>C#CCOCc1nnc(CNC(=O)CN2C(=O)c3ccccc3C2=O)n1-c1ccc(Cl)cc1C(=O)c1ccccc1 -US04006145,2,CO.O=C(O)c1cc(C(F)(F)F)ccc1Sc1ccccc1>>COC(=O)c1cc(C(F)(F)F)ccc1Sc1ccccc1 -US20090099355A1,1,BrCc1ccccc1.Oc1cc(Br)ccc1/C=N/c1ccccc1>>Brc1ccc(/C=N/c2ccccc2)c(OCc2ccccc2)c1 -US08518972B2,1,O=C(N1CCNCC1)C(F)(F)F.O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1>>O=C1CCC(N2Cc3c(OCc4ccc(CN5CCN(C(=O)C(F)(F)F)CC5)cc4)cccc3C2=O)C(=O)N1 -US20050267133A1,2,CN(C)CCN1CCNCC1.O=C(O)c1ccc(/C=N/Nc2ncnc3c2cnn3-c2ccccc2)cc1>>CN(C)CCN1CCN(C(=O)c2ccc(C=NNc3ncnc4c3cnn4-c3ccccc3)cc2)CC1 -US04366158,4,C=CC=O.Nc1ccccc1N1CCCC1=O>>O=C1CCCN1c1cccc2cccnc12 -US20080312192A1,7,CN1CCN(C(=O)c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)CC1>>CN1CCN(C(=O)c2cc(N)cc(C(F)(F)F)c2)CC1 -US08957077B2,1,CCOC(=O)c1cc(Cl)n2nccc2n1.Cn1cc(CN)cn1>>CCOC(=O)c1cc(NCc2cnn(C)c2)n2nccc2n1 -US20090076074A1,6,CCn1ccc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(C(=O)OC)cc34)cc2)n1>>CCn1ccc(NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(C(=O)O)cc34)cc2)n1 -US20080161290A1,1,CCc1cc(OC)cc2nc(-c3cccnc3F)oc(=O)c12.O=S1(=O)CCN([C@@H]2CCNC2)CC1>>CCc1cc(OC)cc2nc(-c3cccnc3N3CCC(N4CCS(=O)(=O)CC4)C3)oc(=O)c12 -US08754114B2,3,CNC(=O)Nc1cccc(B2OC(C)(C)C(C)(C)O2)c1.COC(=O)c1cccc(-c2cnn3c(I)cnc3c2)c1>>CNC(=O)Nc1cccc(-c2cnc3cc(-c4cccc(C(=O)OC)c4)cnn23)c1 -US03950236,7,COc1ccc(CC(=O)c2cc(OC)c(OC)cc2C)cc1OC>>COc1ccc(CCc2cc(OC)c(OC)cc2C)cc1OC -US07235661B2,1,O=Cc1csc2ccccc12.c1ccc(N2CCNCC2)nc1>>c1ccc(N2CCN(Cc3csc4ccccc34)CC2)nc1 -US20130217709A1,6,CCOC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@@H](NC(=O)OCc2ccccc2)[C@H](C(=O)O)C1 -US05196570,1,C=[N+]=[N-].CCCCCCCCC(O)/C=C/C=C/c1ccccc1CCCCC(=O)O>>CCCCCCCCC(O)/C=C/C=C/c1ccccc1CCCCC(=O)OC -US08183262B2,3,CC(C)(C)NS(=O)(=O)c1cccc(B(O)O)c1.CCOc1cc(-c2cc(C(F)(F)F)nc(-c3ccnc(Cl)c3)n2)ccc1C(F)(F)F>>CCOc1cc(-c2cc(C(F)(F)F)nc(-c3ccnc(-c4cccc(S(=O)(=O)NC(C)(C)C)c4)c3)n2)ccc1C(F)(F)F -US20140155407A1,3,Brc1ccc(Cn2ccnc2)cn1.COc1ccc(B(O)O)cc1OC>>COc1ccc(-c2ccc(Cn3ccnc3)cn2)cc1OC -US20130217702A1,2,COc1cc(C(=O)NC2(C(=O)O)CC2)on1.Cc1cnc(-c2c(Cl)c3ccccc3n2-c2ccc(CN)cc2)o1>>COc1cc(C(=O)NC2(C(=O)NCc3ccc(-n4c(-c5ncc(C)o5)c(Cl)c5ccccc54)cc3)CC2)on1 -US06066639,3,C#Cc1cnc2nc(NC(=O)C(C)(C)C)nc(O)c2c1.COC(=O)CC[C@H](NC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(I)n1)C(=O)OC>>COC(=O)CC[C@H](NC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(C#Cc2cnc3nc(NC(=O)C(C)(C)C)nc(O)c3c2)n1)C(=O)OC -US04710468,7,CCCCOC(=O)CC(=O)CCl>>CCCCOC(=O)C[C@@H](O)CCl -US06723722B1,1,CCOC(=O)CBr.COC(CNS(=O)(=O)c1ccc2cc(Cl)ccc2c1)OC>>CCOC(=O)CN(CC(OC)OC)S(=O)(=O)c1ccc2cc(Cl)ccc2c1 -US09045469B2,1,OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2.OCCBr>>OCC[N+]12CCC(C(O)(c3ccccc3)c3ccccc3)(CC1)CC2 -US20060058308A1,1,CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(Cl)n3)cccc2s1.CC(O)c1ccc(F)cc1>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(OC(C)c4ccc(F)cc4)n3)cccc2s1 -US20150246922A1,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1c2n(c3c(Br)cc(Cl)cc13)CCNC2=O>>Cc1c2n(c3c(-c4ccc(N)nc4)cc(Cl)cc13)CCNC2=O -US20110053931A1,2,COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCOCC1.O=C(O)C12CC1CN(c1ccc(F)cc1)C2=O>>COc1cc2c(Oc3ccc(NC(=O)C45CC4CN(c4ccc(F)cc4)C5=O)cc3F)ccnc2cc1OCCCN1CCOCC1 -US04923891,6,CCOC(=O)CCC1(CCC(=O)OCC)OC(CSC(C)=O)CS1>>CCOC(=O)CCC1(CCC(=O)OCC)OC(CS)CS1 -US20050131014A1,6,CCOC(=O)c1ccc(NC(=O)Nc2cccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1>>O=C(Nc1ccc(C(=O)O)cc1)Nc1cccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 -US20150057265A1,7,C=C(C)c1cnc2c(NC(=O)OC(C)(C)C)c(C(=O)OCC)oc2c1>>CCOC(=O)c1oc2cc(C(C)C)cnc2c1NC(=O)OC(C)(C)C -US04649153,2,CCO.Cc1cc2c(s1)C(C(=O)O)CC2>>CCOC(=O)C1CCc2cc(C)sc21 -US20090062328A1,1,CONCc1nc2c(N)nc(C)c(C)c2n1CC(C)C.O=C(Cl)C1CC1>>CON(Cc1nc2c(N)nc(C)c(C)c2n1CC(C)C)C(=O)C1CC1 -US08455638B2,6,CCOC(=O)c1cnn(-c2nc(-c3ccccc3OC)cs2)c1C(F)(F)F>>CCOC(=O)c1cnn(-c2nc(-c3ccccc3O)cs2)c1C(F)(F)F -US08143271B2,3,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Br)cc23)c1F.OB(O)c1cccnc1>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4cccnc4)cc23)c1F -US20110003820A1,2,CC1NCCn2c(-c3ccccn3)nnc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2nnc(-c3ccccn3)n2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US20080255195A1,6,CC(C)(C)OC(=O)Cc1cc(F)c([N+](=O)[O-])c(F)c1>>O=C(O)Cc1cc(F)c([N+](=O)[O-])c(F)c1 -US20100019669A1,3,Brc1ccc(Br)nc1.OB(O)c1ccccc1>>Brc1ccc(-c2ccccc2)nc1 -US04254138,7,CCCCCCCCCCCCCCCCNc1ccc(C(=O)OC=CC(=O)OCC)cc1>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)OCCC(=O)OCC)cc1 -US06071908,1,C=O.CS(=O)(=O)N1CC(CCl)c2ccc(NCc3ccc([N+](=O)[O-])cc3)cc21>>CN(Cc1ccc([N+](=O)[O-])cc1)c1ccc2c(c1)N(S(C)(=O)=O)CC2CCl -US04429128,7,CCN1CCN(C(=O)NC(C(=O)NC2C(=O)N3C(C(=O)OCc4ccc5ccccc5c4)C(C)C(=O)[C@H]23)c2ccccc2)C(=O)C1=O>>CCN1CCN(C(=O)NC(C(=O)NC2C(=O)N3C(C(=O)OCc4ccc5ccccc5c4)C(C)C(O)[C@H]23)c2ccccc2)C(=O)C1=O -US20140213580A1,2,N#Cc1cc(-c2cccnc2)c(C2CC2)nc1N1CCN[C@H](C2CC2)C1.O=C(O)CC(F)(F)F>>N#Cc1cc(-c2cccnc2)c(C2CC2)nc1N1CCN(C(=O)CC(F)(F)F)[C@H](C2CC2)C1 -US05716974,3,COC(=O)Cc1c(C)nc2sc(-c3ccc(OC)cc3)nn12.COC=O>>COC=C(C(=O)OC)c1c(C)nc2sc(-c3ccc(OC)cc3)nn12 -US05272147,6,CCCOc1ccc(/C=C/C(=O)OC(C)(C)C)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1>>CCCOc1ccc(/C=C/C(=O)O)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1 -US08497368B2,4,Nc1ccc(Br)c(F)c1.OCC(O)CO>>Fc1cc2ncccc2cc1Br -US07456286B2,2,CCOC(=O)c1cc2c(ccc(=O)n2-c2ccccc2)n1Cc1cccc(Cl)c1.NN>>NNC(=O)c1cc2c(ccc(=O)n2-c2ccccc2)n1Cc1cccc(Cl)c1 -US06492373B2,9,COc1ccc(C(=O)CN2CCN(c3cc4c(cc3F)c(=O)c(C(=O)O)cn4-c3ccc([N+](=O)[O-])cc3F)CC2)cc1.NO>>COc1ccc(C(CN2CCN(c3cc4c(cc3F)c(=O)c(C(=O)O)cn4-c3ccc([N+](=O)[O-])cc3F)CC2)=NO)cc1 -US20120101137A1,6,COC(=O)c1cc(C2CCCN2C(=O)OC(C)(C)C)sc1C>>COC(=O)c1cc(C2CCCN2)sc1C -US20050032786A1,1,CC(C)S.N#Cc1cccc(Cl)n1>>CC(C)Sc1cccc(C#N)n1 -US20060074121A1,6,CC(C)(C)OC(=O)N1CC2CN(Cc3ccccc3)CC2C1>>CC(C)(C)OC(=O)N1CC2CNCC2C1 -US20130030031A1,6,COc1cccc2c1c(N(S(=O)(=O)c1ccc(Cl)s1)S(=O)(=O)c1ccc(Cl)s1)nn2C(=O)OC(C)(C)C>>COc1cccc2[nH]nc(N(S(=O)(=O)c3ccc(Cl)s3)S(=O)(=O)c3ccc(Cl)s3)c12 -US20090312310A1,6,CN1C[C@H]2[C@H](C1)NC(=O)CN2C(=O)OC(C)(C)C>>CN1C[C@@H]2NCC(=O)N[C@H]2C1 -US20070293502A1,7,CCN(CC)C(=O)c1ccc([C@H](c2cccc([N+](=O)[O-])c2)N2CCN(CCOC)CC2)cc1>>CCN(CC)C(=O)c1ccc([C@H](c2cccc(N)c2)N2CCN(CCOC)CC2)cc1 -US08063046B2,2,COc1ccc(C(N)=O)cc1C(=O)O.Nc1ccc2[nH]ccc2c1>>COc1ccc(C(N)=O)cc1C(=O)Nc1ccc2[nH]ccc2c1 -US05804588,1,CI.Cc1ccc2cccc(O)c2n1>>COc1cccc2ccc(C)nc12 -US05075299,3,C1COCCN1.C=O.O=c1cc(CO)occ1O>>O=c1cc(CO)oc(CN2CCOCC2)c1O -US05021436,6,CCOC(=O)C1=C(CSCC(OCC)OCC)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1>>CCOC(=O)C1=C(CSCC=O)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 -US20030191323A1,2,Nc1ccccc1S(N)(=O)=O.O=C(O)c1cccc(OCc2ccc([N+](=O)[O-])cc2)c1>>NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccc([N+](=O)[O-])cc2)c1 -US20080085886A1,2,CC1(C)OC[C@H](CON)O1.CCOC(=O)c1oc2ccncc2c1Nc1cc(F)c(I)cc1F>>CC1(C)OC[C@H](CONC(=O)c2oc3ccncc3c2Nc2cc(F)c(I)cc2F)O1 -US20140171404A1,5,C#CCCN.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C#CCCNC(=O)OC(C)(C)C -US06861424B2,6,CCOC(=O)N1CCN(C(=O)C(Cc2cccc(C(=O)OC)c2)C(=O)Nc2ccc3ccccc3c2)CC1>>CCOC(=O)N1CCN(C(=O)C(Cc2cccc(C(=O)O)c2)C(=O)Nc2ccc3ccccc3c2)CC1 -US07235676B2,4,C=Cc1ccccc1.OO>>c1ccc(C2CO2)cc1 -US06204277B1,6,COC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)OC>>COC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O -US20050148631A1,2,CNc1cccc(C)n1.N#Cc1ccc(-c2ccc(S(=O)(=O)Cl)cc2)cc1>>Cc1cccc(N(C)S(=O)(=O)c2ccc(-c3ccc(C#N)cc3)cc2)n1 -US08575154B2,3,Nc1ncccc1Br.OB(O)c1ccc(O)cc1>>Nc1ncccc1-c1ccc(O)cc1 -US20150025068A1,2,COCCO.O=C(O)c1ccc(NS(=O)(=O)c2cc(Cl)sc2Cl)cc1O>>COCCOC(=O)c1ccc(NS(=O)(=O)c2cc(Cl)sc2Cl)cc1O -US20100298343A1,4,C=CCOc1ccc(NN)cc1.CCOC(=O)CC(=O)CSC>>C=CCOc1ccc2[nH]c(CC(=O)OCC)c(SC)c2c1 -US20150225367A1,6,COCCS(=O)(=O)NC1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1>>O=S(=O)(CCO)NC1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1 -US20090118261A1,1,CNC.COC(=O)c1ccc(CBr)c(C(F)(F)F)c1>>COC(=O)c1ccc(CN(C)C)c(C(F)(F)F)c1 -US20120114765A1,1,CC(=O)c1cc([N+](=O)[O-])c(Cl)s1.Sc1ccc(Cl)cc1Cl>>CC(=O)c1cc([N+](=O)[O-])c(Sc2ccc(Cl)cc2Cl)s1 -US20110212956A1,2,CC1NCCc2c(-c3ccco3)cccc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2cccc(-c3ccco3)c2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US05075440,1,C=O.CCOC(=O)C1=C(C)NC2=C(C1c1cccc(Cl)c1Cl)S(=O)(=O)CCNC2>>CCOC(=O)C1=C(C)NC2=C(C1c1cccc(Cl)c1Cl)S(=O)(=O)CCN(C)C2 -US08304539B2,6,CNC(=O)c1cnc(NC(=O)OC(C)(C)C)s1>>CNC(=O)c1cnc(N)s1 -US06238752B1,1,O=C1C=C(c2ccccc2)C(=O)N1.O=[N+]([O-])c1cc(CO)cc([N+](=O)[O-])c1>>O=C1C=C(c2ccccc2)C(=O)N1Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 -US07915411B2,7,O=C(Nc1ccc(Sc2ccc(O)cc2)c([N+](=O)[O-])c1)c1cccc(C(F)(F)F)c1>>Nc1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1Sc1ccc(O)cc1 -US06492403B1,4,Cc1sc(C(=O)OC(C)C)cc1C(=O)CBr.NC(N)=S>>Cc1sc(C(=O)OC(C)C)cc1-c1csc(N)n1 -US08569494B2,3,CC(C)(O)c1ccc([Sn](C)(C)C)cn1.O=C1CN(CC2CCOCC2)c2nc(Br)cnc2N1>>CC(C)(O)c1ccc(-c2cnc3c(n2)N(CC2CCOCC2)CC(=O)N3)cn1 -US08211919B2,2,CC(C)(C)OC(=O)N(CC(=O)O)c1ccccc1.Nc1ccc(-c2ccncc2)cc1>>CC(C)(C)OC(=O)N(CC(=O)Nc1ccc(-c2ccncc2)cc1)c1ccccc1 -US20150225404A1,6,CC(C)(C)[Si](C)(C)OCc1cncc(-c2cc(OCc3cccc(F)n3)nc3c2CCCC3)n1>>OCc1cncc(-c2cc(OCc3cccc(F)n3)nc3c2CCCC3)n1 -US06511997B1,2,Nc1n[nH]c(-c2ccc(F)cc2)c1-c1ccncc1.O=C(O)CC1CCCCC1>>O=C(CC1CCCCC1)Nc1n[nH]c(-c2ccc(F)cc2)c1-c1ccncc1 -US05403859,1,CC1(C)CC(O)(c2cccc(OCc3ccccc3)c2)CCO1.CI>>COC1(c2cccc(OCc3ccccc3)c2)CCOC(C)(C)C1 -US20140107161A1,2,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1SCC(=O)O.NCC(F)(F)F>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1SCC(=O)NCC(F)(F)F -US20060019961A1,2,CC[C@H]1Nc2ccc(F)cc2NC1=O.COc1cccc(C(=O)Cl)c1>>CC[C@@H]1C(=O)Nc2cc(F)ccc2N1C(=O)c1cccc(OC)c1 -US20100216788A1,1,O=[N+]([O-])c1ccc(F)c(Cl)c1.Oc1cccc(Oc2ccccc2)c1>>O=[N+]([O-])c1ccc(Oc2cccc(Oc3ccccc3)c2)c(Cl)c1 -US08765730B2,3,CS(=O)(=O)c1cccc(B(O)O)c1.O/N=C(\CC(c1ccccc1)c1ccc(Br)cc1)c1ccncc1>>CS(=O)(=O)c1cccc(-c2ccc(C(C/C(=N\O)c3ccncc3)c3ccccc3)cc2)c1 -US20120004164A1,1,BrCc1ccncc1.CCOC(=O)c1sc(N2CCNC2=O)nc1C>>CCOC(=O)c1sc(N2CCN(Cc3ccncc3)C2=O)nc1C -US08969336B2,1,CSc1nc(Cl)c(C(N)=O)c(Nc2ccc(C)nc2)n1.C[O-]>>COc1nc(SC)nc(Nc2ccc(C)nc2)c1C(N)=O -US20090233929A1,3,CON(C)C(=O)c1cn(-c2cccc(-c3ccccc3OC(F)(F)F)c2)cn1.COc1cccc(Br)c1>>COc1cccc(C(=O)c2cn(-c3cccc(-c4ccccc4OC(F)(F)F)c3)cn2)c1 -US20070287738A1,1,COCCOc1cc(-c2cncc(C#N)c2Cl)ccc1OC.COc1cc(N)c(Cl)cc1Cl>>COCCOc1cc(-c2cncc(C#N)c2Nc2cc(OC)c(Cl)cc2Cl)ccc1OC -US20070155967A1,1,NCc1ccccc1N.O=C1CCC(Br)C(=O)N1>>Nc1ccccc1CNC1CCC(=O)NC1=O -US08466295B2,3,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)NC(Cc2ccccc2)c2cc(Br)cs2)CC1.NC(=O)c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)NC(Cc2ccccc2)c2cc(-c3ccc(C(N)=O)cc3)cs2)CC1 -US20100130489A1,1,FC(F)(F)Oc1ccc2c(c1)nc(Cl)c1ncc(Br)n12.NCCCO>>OCCCNc1nc2cc(OC(F)(F)F)ccc2n2c(Br)cnc12 -US06087390,1,CC(C)C1=CC2CC3(C=O)C4CCC(C)C4CC2(COC24OC5C(O)C(OC5(O[SiH](C)C)O2)C4C(C)(C)C)C13C(=O)OC(c1ccccc1)c1ccccc1.CCCCCCCl>>CCCCCCOC1C2OC3(O[SiH](C)C)OC(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)OC(c4ccccc4)c4ccccc4)(OC13)C2C(C)(C)C -US20150057260A1,3,CCOC(=O)c1cc(Cl)nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1.OB(O)c1cc(F)cc(F)c1>>CCOC(=O)c1cc(-c2cc(F)cc(F)c2)nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)n1 -US20060287309A1,1,O=CCCCOc1nc2c(cc1Br)CCC(=O)N2.c1ccc2c(N3CCNCC3)cccc2c1>>O=C1CCc2cc(Br)c(OCCCCN3CCN(c4cccc5ccccc45)CC3)nc2N1 -US05633375,4,CCOC(=O)C(Cl)C=O.NC(=S)C(F)(F)F>>CCOC(=O)c1cnc(C(F)(F)F)s1 -US20030017948A1,2,CCOC(=O)Cl.CCS(=O)(=O)Nc1cc(N)c(F)cc1Br>>CCOC(=O)Nc1cc(NS(=O)(=O)CC)c(Br)cc1F -US20100298290A1,1,Nc1ccccc1.Oc1cc(Cl)ncn1>>Oc1cc(Nc2ccccc2)ncn1 -US20150057271A1,1,CC(C)(O)CCl.Oc1ccccc1Br>>CC(C)(O)COc1ccccc1Br -US09102665B2,2,O=C(O)c1ccccc1CCC(O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1>>O=C1OC(c2cccc(/C=C/c3ccc4ccc(Cl)cc4n3)c2)CCc2ccccc21 -US20080090818A1,3,NC(=O)c1cc(B(O)O)cs1.O=C(Cc1ccccc1)Nc1ccc(Nc2ncc(Br)n3ncnc23)cn1>>NC(=O)c1cc(-c2cnc(Nc3ccc(NC(=O)Cc4ccccc4)nc3)c3ncnn23)cs1 -US20060030558A1,6,O=C(OCc1ccccc1)N1CCCCC1c1ncc(-c2ccccc2)o1>>c1ccc(-c2cnc(C3CCCCN3)o2)cc1 -US06525042B1,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3cccc[n+]3[O-])cc2)CC1>>O=C(c1ccc(-c2cccc[n+]2[O-])cc1)N1CCNCC1 -US20140323463A1,2,C=CC(=O)Cl.CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1Oc1cccc(N)c1>>C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)c(C(N)=O)nc2CC)c1 -US08003785B2,2,COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C.NCC1CCCCC1>>COc1cc(C(=O)NCC2CCCCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20090306067A1,1,COc1cc(C(=O)OCc2ccccc2)ccc1N.FC(F)(F)c1cnc(Cl)nc1Cl>>COc1cc(C(=O)OCc2ccccc2)ccc1Nc1ncc(C(F)(F)F)c(Cl)n1 -US06664271B1,2,CC(C(=O)O)c1ccccc1.CCOC(=O)[C@H]1CCCNC1>>CCOC(=O)C1CCCN(C(=O)C(C)c2ccccc2)C1 -US05723475,7,C1=C(c2ccc(Oc3ccccc3)cc2)CCNC1>>c1ccc(Oc2ccc(C3CCNCC3)cc2)cc1 -US20090124676A1,1,C1=COCCC1.CCCCCCCC[C@H]1[C@H](O)C[C@@H]2OC(=O)C[C@@H]21>>CCCCCCCC[C@H]1[C@H](OC2CCCCO2)C[C@@H]2OC(=O)C[C@@H]21 -US07691843B2,1,CI.COc1cc(C(=O)O)cc(CCCO)c1OC>>COCCCc1cc(C(=O)O)cc(OC)c1OC -US20030187026A1,6,CC(C)(C)OC(=O)n1nc(-c2ccncc2)c2cc(O[Si](C)(C)C(C)(C)C)cnc21>>CC(C)(C)OC(=O)n1nc(-c2ccncc2)c2cc(O)cnc21 -US20150018373A1,1,Cc1c2cc(-n3ccc(O)cc3=O)ccc2nn1C.OCc1cccc(Cl)c1>>Cc1c2cc(-n3ccc(OCc4cccc(Cl)c4)cc3=O)ccc2nn1C -US05596097,6,COc1ccc(COc2cncc3c2-c2nn(C)c4ccc(NCCN(C)C)c(c24)C3=O)cc1>>CN(C)CCNc1ccc2c3c(nn2C)-c2c(O)cncc2C(=O)c13 -US20020165264A1,1,CO.O=c1c(Cl)c(Cl)c1=O>>COc1c(Cl)c(=O)c1=O -US08969346B2,7,C=Cc1ccc(NCC(C)(C)c2ccc(F)cc2)nn1>>CCc1ccc(NCC(C)(C)c2ccc(F)cc2)nn1 -US06251926B1,6,CCOC(=O)/C(=N/OCc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)c1cccnc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(/C(=O)O)c2cccnc2)cc1 -US20140288123A1,2,Cc1cc(C)c(CN)c(O)n1.Cc1ccc(OC(C)c2ccc(C(=O)O)cc2)cc1>>Cc1ccc(OC(C)c2ccc(C(=O)NCc3c(C)cc(C)nc3O)cc2)cc1 -US20110046131A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](CNc2nc(Cl)ncc2[N+](=O)[O-])C1.NCc1ccc(F)c(F)c1>>CC(C)(C)OC(=O)N1CCC[C@@H](CNc2nc(NCc3ccc(F)c(F)c3)ncc2[N+](=O)[O-])C1 -US20120184553A1,2,CN(C)C(=O)c1ccc(OCc2ccccc2)c(C(=O)O)c1.Nc1cccnc1>>CN(C)C(=O)c1ccc(OCc2ccccc2)c(C(=O)Nc2cccnc2)c1 -US06368608B1,3,C#CC(O)c1cc2c(cc1C)C(C)(C)CCC2(C)C.CC(=O)Oc1ccc(I)cc1>>CC(=O)Oc1ccc(C#CC(O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1 -US20100227880A1,7,CCOC(=O)c1nc2ccccn2c1-c1cccnc1>>OCc1nc2ccccn2c1-c1cccnc1 -US06005103,7,CCOC(=O)COc1ccc(-c2cc(O)c(SCCc3ccccc3)c(=O)o2)cc1>>O=c1oc(-c2ccc(OCCO)cc2)cc(O)c1SCCc1ccccc1 -US04321200,2,NN1Cc2ccccc2C1.S=C=Nc1ccccc1>>S=C(Nc1ccccc1)NN1Cc2ccccc2C1 -US20040204450A1,1,CCOC(=O)N1c2ccc(C(F)(F)F)cc2C(C(OS(C)(=O)=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC.[N-]=[N+]=[N-]>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2C(C(N=[N+]=[N-])c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC -US20090227620A1,7,CCOC(=O)C=C1CC2CCCC(C1)N2C(=O)OC(C)(C)C>>CCOC(=O)CC1CC2CCCC(C1)N2C(=O)OC(C)(C)C -US20140038999A1,6,Cc1nccc2c1c(=O)n(C)c1cc(OC[C@H](CC(C)C)NC(=O)OC(C)(C)C)c(C(F)F)cc21>>Cc1nccc2c1c(=O)n(C)c1cc(OC[C@@H](N)CC(C)C)c(C(F)F)cc21 -US20090203681A1,3,C=CC(=O)Nc1ccccc1NC(=O)OC(C)(C)C.O=Cc1ccc(Br)cc1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)/C=C/c1ccc(C=O)cc1 -US20040106604A1,7,O=C1CC(C(=O)c2ccccc2)CO1>>O=C1CC(Cc2ccccc2)CO1 -US20120004216A1,2,Nc1nc(-c2ccccc2)c(-c2ccccc2)s1.O=C(Cl)c1ccccc1>>O=C(Nc1nc(-c2ccccc2)c(-c2ccccc2)s1)c1ccccc1 -US20140288043A1,6,COc1ccc(Cn2nc(-c3cc(C(F)(F)F)ncn3)c3c(NC(C)C)nccc32)cc1>>CC(C)Nc1nccc2[nH]nc(-c3cc(C(F)(F)F)ncn3)c12 -US04851410,6,O=C(c1cnn(OCCCC2OCCO2)c1)N1CCCCC1>>O=CCCCOn1cc(C(=O)N2CCCCC2)cn1 -US04962234,1,CC(=O)c1ccccc1.CCOC(=O)c1ccccc1N>>CCOC(=O)c1ccccc1N=C(C)c1ccccc1 -US20110230497A1,3,CC(=O)N1CCC(CC(=O)Nc2ccc(Br)cn2)CC1.OB(O)c1ccccc1F>>CC(=O)N1CCC(CC(=O)Nc2ccc(-c3ccccc3F)cn2)CC1 -US08293902B2,1,CC(=O)N1CCNCC1.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCBr>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCN(C(C)=O)CC1 -US04908475,2,O=C(O)CC1(CC(=O)O)CCCCC1>>O=C1CC2(CCCCC2)CC(=O)O1 -US20150080438A1,1,O=S(CCCNCCO)CCCC(F)(F)C(F)(F)F.Oc1cccc(C2=C(CCCCCCBr)c3ccc(O)cc3CCC2)c1>>O=S(CCCN(CCO)CCCCCCC1=C(c2cccc(O)c2)CCCc2cc(O)ccc21)CCCC(F)(F)C(F)(F)F -US07205326B2,1,O=[N+]([O-])c1ccc(OCCCCl)cc1.c1c[nH]nn1>>O=[N+]([O-])c1ccc(OCCCn2ccnn2)cc1 -US06995182B2,1,Cc1ccc(S(=O)(=O)N2C(CCCCl)CCC2c2ccc(F)cc2)cc1.c1nnn[nH]1>>Cc1ccc(S(=O)(=O)N2C(CCCn3cnnn3)CCC2c2ccc(F)cc2)cc1 -US20140315901A1,3,CCCC[Sn](CCCC)(CCCC)c1cc(C)ccn1.C[Si](C)(C)CCOCn1cc(C#N)c2c(I)cc(Cl)nc21>>Cc1ccnc(-c2cc(Cl)nc3c2c(C#N)cn3COCC[Si](C)(C)C)c1 -US06492360B1,1,CCI.COc1ccc2c(Cc3c(Cl)cncc3Cl)n[nH]c(=O)c2c1>>CCn1nc(Cc2c(Cl)cncc2Cl)c2ccc(OC)cc2c1=O -US20140243336A1,6,COc1cc(C)nc(Nc2cc(N[C@@H]3CS(=O)(=O)CC[C@@H]3NC(=O)OC(C)(C)C)cnc2C#N)c1>>COc1cc(C)nc(Nc2cc(N[C@@H]3CS(=O)(=O)CC[C@@H]3N)cnc2C#N)c1 -US20090233896A1,2,CC(C)(C)OC(=O)NCCN.O=C(O)c1cncc(-c2cnc(Nc3ncccc3Cl)s2)c1>>CC(C)(C)OC(=O)NCCNC(=O)c1cncc(-c2cnc(Nc3ncccc3Cl)s2)c1 -US20090149501A1,2,CC(C)(C)OC(=O)N1CCN(CCO)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCN(CCOS(C)(=O)=O)CC1 -US20070213325A1,4,CC(Br)C(=O)c1ccccc1.CNc1nccc(-c2cccnc2Oc2ccc(NC(=N)N)cc2)n1>>CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc(-c4ccccc4)c(C)[nH]3)cc2)n1 -US20060004043A1,7,CCOC(=O)CN1CCCCC1C>>CC1CCCCN1CCO -US20040006081A1,7,CCOC(=O)/C=C(\C)c1cccc(C(F)(F)F)c1>>CCOC(=O)CC(C)c1cccc(C(F)(F)F)c1 -US20120136003A1,2,CCOC(=O)c1nnc(-c2ccc(NS(=O)(=O)C(F)(F)F)cc2)o1.CNCc1ccc(Cl)c(Cl)c1>>CN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1nnc(-c2ccc(NS(=O)(=O)C(F)(F)F)cc2)o1 -US20040147586A1,3,O=C1Cc2ccc(-c3ccccc3)cc2N1.O=Cc1cc2cc(OCCN3CCOCC3)ccc2[nH]1>>O=C1Nc2cc(-c3ccccc3)ccc2C1=Cc1cc2cc(OCCN3CCOCC3)ccc2[nH]1 -US20120015907A1,1,CI.CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(NS(C)(=O)=O)c(I)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(N(C)S(C)(=O)=O)c(I)cc12 -US08987254B2,6,N#Cc1ccc(C(=O)Nc2cccc([C@]34CN(c5ncc(F)cn5)C[C@H]3CSC(NC(=O)c3ccccc3)=N4)c2)nc1>>N#Cc1ccc(C(=O)Nc2cccc([C@]34CN(c5ncc(F)cn5)C[C@H]3CSC(N)=N4)c2)nc1 -US05783522,1,CN(C)C(=S)Cl.Oc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1Cl>>CN(C)C(=S)Oc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1Cl -US20110003787A1,2,CC[C@@H](N)CO.COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc(-c2ccc(C(=O)O)[nH]2)c1>>CC[C@H](CO)NC(=O)c1ccc(-c2cc(Oc3ccc(S(C)(=O)=O)nc3)cc(O[C@@H](C)COC)c2)[nH]1 -US05616579,2,NC/C=C\COc1cc(CN2CCCCC2)ccn1.O=C(O)c1cc[nH]n1>>O=C(NC/C=C\COc1cc(CN2CCCCC2)ccn1)c1cc[nH]n1 -US20110028467A1,6,COc1ccc(C(=O)N2CCOc3cnccc32)cc1C(F)(F)F>>O=C(c1ccc(O)c(C(F)(F)F)c1)N1CCOc2cnccc21 -US04743685,9,O=c1cc(CCl)[nH]cc1OCc1ccccc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1cc(=O)c(OCc2ccccc2)c[nH]1 -US20070105842A1,4,C#CCc1ccccc1.[N-]=[N+]=Nc1cccc(Cl)c1Cl>>Clc1cccc(-n2nncc2Cc2ccccc2)c1Cl -US08344135B2,2,CCc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Oc1ccc2nc(N)sc2n1.O=C(Cl)CCl>>CCc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Oc1ccc2nc(NC(=O)CCl)sc2n1 -US20050245521A1,1,CC(C)(O)c1ccc(Br)cc1.CI>>COC(C)(C)c1ccc(Br)cc1 -US07943607B2,1,CC1(C)NC(=O)c2ccc(F)cc2O1.COCCl>>COCN1C(=O)c2ccc(F)cc2OC1(C)C -US05576335,1,CC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1O.O=[N+]([O-])c1ccccc1O>>CC(C)(C)c1cc(C(=O)Oc2ccccc2[N+](=O)[O-])cc(C(C)(C)C)c1O -US08426420B2,2,O=C(N[C@@H](CCCCOCc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21.O=C(OC1CCC1)N1CCNCC1>>O=C(N[C@@H](CCCCOCc1ccccc1)C(=O)N1CCN(C(=O)OC2CCC2)CC1)OCC1c2ccccc2-c2ccccc21 -US20070066584A1,2,O=C(Cl)C1CCCC1.O=C(N1CCC2(CCNC2)CC1)N1CCC[C@H](NC(=O)C23CC4CC(C2)C(O)C(C4)C3)C1>>O=C(C1CCCC1)N1CCC2(CCN(C(=O)N3CCC[C@H](NC(=O)C45CC6CC(C4)C(O)C(C6)C5)C3)CC2)C1 -US06727264B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccccc3)CC2)c1.COc1ccc(NN)cc1>>COc1ccc2[nH]c(-c3ccccc3)c(CCCN3CCC(c4cccc(NC(=O)C(C)C)c4)CC3)c2c1 -US20060211740A1,6,C[C@H](NC(=O)OC(C)(C)C)C(=O)NC1CCCCC1>>C[C@H](N)C(=O)NC1CCCCC1 -US08399674B2,1,Clc1ccc2nc(NCCOc3ccccc3)ccc2c1.NCc1cccnc1>>c1ccc(OCCNc2ccc3cc(NCc4cccnc4)ccc3n2)cc1 -US08440666B2,6,COCOCC1C(N2C(=O)c3ccccc3C2=O)CC2CC1C2(C)C>>CC1(C)C2CC(N3C(=O)c4ccccc4C3=O)C(CO)C1C2 -US04051256,2,NC1CCCCC1.S=C=Nc1ccc(Cl)cc1>>S=C(Nc1ccc(Cl)cc1)NC1CCCCC1 -US20060052348A1,4,CCCCc1oc2ccccc2c1-c1ncc(-c2ccc3c(Br)c(OCC#N)ccc3c2)o1.[N-]=[N+]=[N-]>>CCCCc1oc2ccccc2c1-c1ncc(-c2ccc3c(Br)c(OCc4nnn[nH]4)ccc3c2)o1 -US05652233,7,C=CCOC(=O)c1cc([N+](=O)[O-])ccc1OCC=C>>C=CCOC(=O)c1cc(N)ccc1OCC=C -US08609669B2,2,Cc1cnc2c(C(C)(C)C)c(N)nn2c1.O=C(Cl)CCC1CCCCC1>>Cc1cnc2c(C(C)(C)C)c(NC(=O)CCC3CCCCC3)nn2c1 -US20100125089A1,2,CC(N)(C#N)Cn1nc2c(Br)cc(Cl)c(Br)c2n1.N#Cc1ccc(C(=O)Cl)cc1>>CC(C#N)(Cn1nc2c(Br)cc(Cl)c(Br)c2n1)NC(=O)c1ccc(C#N)cc1 -US20150152058A1,9,CNc1cnc(Cl)cc1-c1cc(F)ccc1C>>CNc1cnccc1-c1cc(F)ccc1C -US20140005168A1,1,C1CNCCN1.Fc1cccc(-n2ncc3cnc(-c4cncc(C5CC5)c4)cc32)n1>>c1cc(N2CCNCC2)nc(-n2ncc3cnc(-c4cncc(C5CC5)c4)cc32)c1 -US20040225146A1,3,CCOP(=O)(OCC)C(F)(F)Br.COC(=O)C=Cc1ccc(I)cc1>>CCOP(=O)(OCC)C(F)(F)c1ccc(C=CC(=O)OC)cc1 -US06440965B1,2,CC(=O)OC(C)=O.Nc1ncc(Oc2ccc(Cl)cc2)c(N2CCNCC2)n1>>CC(=O)N1CCN(c2nc(N)ncc2Oc2ccc(Cl)cc2)CC1 -US20090062252A1,9,CCOC(=O)[C@H]1CCCN(C(=O)c2ccc(-c3noc(C(F)(F)F)c3C)s2)C1.N>>Cc1c(-c2ccc(C(=O)N3CCC[C@H](C(N)=O)C3)s2)noc1C(F)(F)F -US07173043B2,1,BrCCCCOc1ccc2c(-c3ccc(Br)cc3)csc2c1.C1CCNC1>>Brc1ccc(-c2csc3cc(OCCCCN4CCCC4)ccc23)cc1 -US05403859,1,COC1(c2cc(O)cc(F)c2)CCOCC1.FC(F)(F)c1cccc2cc(CBr)ccc12>>COC1(c2cc(F)cc(OCc3ccc4c(C(F)(F)F)cccc4c3)c2)CCOCC1 -US20110086860A1,6,Cc1ncc(Cl)cc1CN1C(=O)c2ccccc2C1=O>>Cc1ncc(Cl)cc1CN -US08765730B2,1,CCOC(=O)c1cc(B(O)O)ccc1Cl.Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(O)c(F)c1>>CCOC(=O)c1cc(Oc2ccc(C(CC(=O)c3ccc(=O)n(C)c3)c3ccc(Cl)cc3C)cc2F)ccc1Cl -US04128564,7,CCCCC(C)(C)C(O)C#CCC(CCCCCCC(=O)O)S(C)(=O)=O>>CCCCC(C)(C)C(O)CCCC(CCCCCCC(=O)O)S(C)(=O)=O -US06437147B1,7,CNC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1>>CNCc1ccccc1-c1ccc(C(F)(F)F)cc1 -US20130261178A1,1,ClCC1CO1.Oc1ccc(OCCOCC2CC2)cc1>>c1cc(OCC2CO2)ccc1OCCOCC1CC1 -US07875636B2,2,CC(C)(O)c1ccc(CC(=O)O)cc1.C[C@@H](N)c1ccc(OCC(F)(F)F)cn1>>C[C@@H](NC(=O)Cc1ccc(C(C)(C)O)cc1)c1ccc(OCC(F)(F)F)cn1 -US06593322B1,2,COc1ccc2c(c1)CCNC2Cc1ccc(OCc2ccccc2)cc1.O=C(Cl)c1ccc(F)cc1>>COc1ccc2c(c1)CCN(C(=O)c1ccc(F)cc1)C2Cc1ccc(OCc2ccccc2)cc1 -US20130178478A1,1,COC(=O)c1nnc(Cl)cc1Cl.Nc1cccc(C2CCC2)n1>>COC(=O)c1nnc(Cl)cc1Nc1cccc(C2CCC2)n1 -US20100324041A1,2,CC(=O)O.CC(C)(C)OC(=O)N1CCN(c2c(C(=O)NN)cnc3[nH]ccc23)CC1>>CC(=O)NNC(=O)c1cnc2[nH]ccc2c1N1CCN(C(=O)OC(C)(C)C)CC1 -US06048864,9,COc1cc2nc(Cl)nc(Cl)c2c(OC2CCC2)c1OC.N>>COc1cc2nc(Cl)nc(N)c2c(OC2CCC2)c1OC -US20150266867A1,9,BrC(Br)(Br)Br.COc1ccc(CN(C(=O)OCc2ccccc2)[C@@H]2C(=O)N(Cc3ccc(OC)cc3OC)[C@@H]2CC=O)cc1>>COc1ccc(CN(C(=O)OCc2ccccc2)[C@@H]2C(=O)N(Cc3ccc(OC)cc3OC)[C@@H]2CC=C(Br)Br)cc1 -US20150266862A1,1,COC(=O)C1(C)CCNC1.O=Cc1cccc(Oc2ccccc2)c1>>COC(=O)C1(C)CCN(Cc2cccc(Oc3ccccc3)c2)C1 -US20100190230A1,6,COC(=O)C1CC1c1cccc(F)c1>>O=C(O)C1CC1c1cccc(F)c1 -US04771046,6,CON=C1CCN(C(=O)OC(C)(C)C)C1>>CON=C1CCNC1 -US20120258986A1,2,COc1cc(-c2ncn(/C=C\C(=O)OC(=O)/C=C\n3cnc(-c4cc(OC)cc(C(F)(F)F)c4)n3)n2)cc(C(F)(F)F)c1.NN>>COc1cc(-c2ncn(/C=C\C(=O)NN)n2)cc(C(F)(F)F)c1 -US20120277279A1,2,NCC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F.O=C(Cl)c1c(Cl)cccc1Cl>>Nc1c(C(=O)NCC(O)(CNC(=O)c2c(Cl)cccc2Cl)C(F)(F)F)cnn1-c1ccc(F)cc1 -US20150141464A1,2,CC(C)c1cccc([C@H](C)N)c1.O=C(O)c1ccc2c(c1)ncn2Cc1ccc(Br)cc1>>CC(C)c1cccc([C@H](C)NC(=O)c2ccc3c(c2)ncn3Cc2ccc(Br)cc2)c1 -US20090325941A1,1,Cc1c(Br)cc(C(C)(C)C)c(O)c1C(=O)O.Oc1ccccc1>>Cc1c(Br)cc(C(C)(C)C)c(O)c1C(=O)Oc1ccccc1 -US05272271,4,CC(C)(CCBr)CC(=O)Cl.CC1(C)Oc2cc3nonc3cc2C(N)C1O>>CC1(C)CCN(C2c3cc4nonc4cc3OC(C)(C)C2O)C(=O)C1 -US04119710,7,CC(C)(C)N(O)CC(=O)c1cc(C#N)c(N)c(C#N)c1>>CC(C)(C)N(O)CC(O)c1cc(C#N)c(N)c(C#N)c1 -US20130096149A1,8,CSc1nccc(-c2sc(C3CC3)nc2-c2cc(Cl)cc(NS(C)(=O)=O)c2F)n1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1nccc(-c2sc(C3CC3)nc2-c2cc(Cl)cc(NS(C)(=O)=O)c2F)n1 -US05021434,9,CCCC(c1cc(Br)cs1)n1ccnc1.N#C[Cu]>>CCCC(c1cc(C#N)cs1)n1ccnc1 -US04910211,6,COc1ccc(-c2nc3c(OC)cccc3s2)cc1>>COc1ccc(-c2nc3c(O)cccc3s2)cc1 -US20030208066A1,1,CCOC(=O)c1cnc2c(cnn2-c2ccccc2)c1Cl.COc1ccc(S(=O)(=O)NCc2ccccc2)cc1>>CCOC(=O)c1cnc2c(cnn2-c2ccccc2)c1N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1 -US20080188466A1,2,CS(=O)(=O)Cl.Nc1ccc([N+](=O)[O-])cc1>>CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1 -US20110263602A1,6,CCOC(=O)c1cn(Cc2ccc(OC)cc2)nc1C(F)(F)F>>COc1ccc(Cn2cc(C(=O)O)c(C(F)(F)F)n2)cc1 -US05877199,1,CI.CSc1c(CC(=O)OC(C)C)cc(C)c2c1[nH]c1ccccc12>>CSc1c(CC(=O)OC(C)C)cc(C)c2c3ccccc3n(C)c12 -US20100190980A1,6,COC(=O)c1nc(Sc2nnc[nH]2)cnc1Sc1ccc(F)cc1>>O=C(O)c1nc(Sc2nnc[nH]2)cnc1Sc1ccc(F)cc1 -US20090156642A1,1,CS(=O)(=O)c1cccc(S(=O)[O-])c1.O=Cc1cc(-c2cccnc2F)c(Br)s1>>CS(=O)(=O)c1cccc(S(=O)(=O)c2sc(C=O)cc2-c2cccnc2F)c1 -US03978127,9,CC(=O)c1ccc(C(F)(F)C(F)(F)c2ccccc2)cc1.NO>>CC(=NO)c1ccc(C(F)(F)C(F)(F)c2ccccc2)cc1 -US07732435B2,4,CC(C)c1oc2c(N)c(N)ccc2c(=O)c1-c1ccc(Cl)cc1.O=C(O)C(F)(F)F>>CC(C)c1oc2c(ccc3[nH]c(C(F)(F)F)nc32)c(=O)c1-c1ccc(Cl)cc1 -US09073922B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.Clc1cnc2[nH]ccc2c1Cl>>Cc1ccc(S(=O)(=O)n2ccc3c(Cl)c(Cl)cnc32)cc1 -US20120178736A1,1,Cc1nc2ccccc2[nH]1.Cn1c(CN2CCC(C3(O)CCC3)CC2)nc2c(N3CCOCC3)nc(Cl)nc21>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C4(O)CCC4)CC3)n(C)c2n1 -US08466180B2,2,Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1C(=O)Cl.Nc1cccc(N)c1>>Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1C(=O)Nc1cccc(N)c1 -US20050197386A1,6,CCCCCC[C@H](C(=O)OC)[C@@H](O)CCCCCOCc1ccccc1>>CCCCCC[C@H](C(=O)O)[C@@H](O)CCCCCOCc1ccccc1 -US20110053943A1,6,CC(C)(C)OC(=O)N1CC[C@@H](Oc2ncc(F)cc2F)C1>>Fc1cnc(O[C@@H]2CCNC2)c(F)c1 -US20050070549A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(Cl)ccc1Br>>Cc1cc(Cl)ccc1N1CCN(C(=O)OC(C)(C)C)CC1 -US20060030583A1,2,CNC.O=C(Cl)c1cncc(Br)c1>>CN(C)C(=O)c1cncc(Br)c1 -US20150225396A1,2,O=C(O)CCCc1nc2ccccc2c(=O)[nH]1.c1cncc(-c2nnc(C3CCNCC3)o2)c1>>O=C(CCCc1nc2ccccc2c(=O)[nH]1)N1CCC(c2nnc(-c3cccnc3)o2)CC1 -US20100197634A1,3,CC(=O)c1cc(Cl)c(Nc2nc3ccc(Br)cc3c3c(=O)[nH]ccc23)c(Cl)c1.C[Mg+]>>CC(C)(O)c1cc(Cl)c(Nc2nc3ccc(Br)cc3c3c(=O)[nH]ccc23)c(Cl)c1 -US09090599B2,2,CC(C)(C)c1nc(CN)cs1.O=C(O)c1cc(-c2ccc(Cl)cc2)c(OCC2CC2)cn1>>CC(C)(C)c1nc(CNC(=O)c2cc(-c3ccc(Cl)cc3)c(OCC3CC3)cn2)cs1 -US20130345215A1,1,Cn1ncc2c(=O)[nH]c(Cl)nc21.Cn1nccc1CN1CCNCC1>>Cn1nccc1CN1CCN(c2nc3c(cnn3C)c(=O)[nH]2)CC1 -US07276608B2,3,Brc1ccsc1.CCCC[Sn](CCCC)(CCCC)c1ccc2c(c1)CC(NC(=O)OC(C)(C)C)C(=O)N2Cc1ccccc1>>CC(C)(C)OC(=O)NC1Cc2cc(-c3ccsc3)ccc2N(Cc2ccccc2)C1=O -US08673942B2,6,CCOC(=O)CC1CN=C(c2cc3cc(Oc4ccc(S(C)(=O)=O)nc4)cc(OC)c3[nH]2)S1>>COc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C3=NCC(CC(=O)O)S3)[nH]c12 -US20060154920A1,3,C=O.NCCN1c2ccccc2C[C@H]2CCC[C@H]21>>c1cc2c3c(c1)C[C@@H]1CCC[C@H]1N3CCNC2 -US07943609B2,6,Nc1nc2ccccc2c2c1nc1n2[C@@H](COCc2ccccc2)COC1>>Nc1nc2ccccc2c2c1nc1n2[C@@H](CO)COC1 -US07355069B2,1,COC(=O)c1ccccc1CBr.O=C(O)Cc1ccc(S)cc1>>COC(=O)c1ccccc1CSc1ccc(CC(=O)O)cc1 -US08461134B2,7,O=C(O)Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(CCO)c1 -US20120010241A1,6,COC(=O)c1cccc2c1c(C(F)(F)F)nn2-c1ccc(C#N)c(N[C@@H]2CC[C@@H](O)CC2)c1>>N#Cc1ccc(-n2nc(C(F)(F)F)c3c(C(=O)O)cccc32)cc1N[C@@H]1CC[C@@H](O)CC1 -US05998471,7,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCC3=O)cc1>>CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCC3O)cc1 -US06818631B1,1,CC(C)Sc1nc(Cl)c(I)c(C(F)(F)F)n1.CCOC(=O)c1c[nH]nc1C(F)(F)F>>CCOC(=O)c1cn(-c2nc(SC(C)C)nc(C(F)(F)F)c2I)nc1C(F)(F)F -US20090005353A1,1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.Cc1cc(CN)no1>>Cc1cc(CNC2=C(c3ccccc3)S(=O)(=O)N(C(C)(C)C)C2=O)no1 -US20150266870A1,2,CCO.O=C(O)Cc1c(F)cccc1Cl>>CCOC(=O)Cc1c(F)cccc1Cl -US20070203072A1,6,CCC[C@H](NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)OC)C1CCCCC1)C(C)C)C(=O)OC(C)(C)C>>CCC[C@H](NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)OC)C1CCCCC1)C(C)C)C(=O)O -US20150238601A1,3,CC1(C)OB(c2cc(F)cc(OCC(=O)NC3CC3)c2)OC1(C)C.Cc1cnc(Cl)nc1Nc1ccc2[nH]ncc2c1>>Cc1cnc(-c2cc(F)cc(OCC(=O)NC3CC3)c2)nc1Nc1ccc2[nH]ncc2c1 -US20050124664A1,7,Cn1nnc(-c2ccc([N+](=O)[O-])cc2)n1>>Cn1nnc(-c2ccc(N)cc2)n1 -US20070037807A1,3,CCOP(=O)(Cc1ccccc1Br)OCC.Cc1ccc(-c2c(C=O)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1>>Cc1ccc(-c2c(/C=C/c3ccccc3Br)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.OCc1ccc(Br)c(F)c1>>CC(C)(C)OC(=O)COc1ccc(Cl)cc1C#Cc1ccc(CO)cc1F -US20100292212A1,7,O=[N+]([O-])c1ccc(OCCC(F)(F)F)cc1>>Nc1ccc(OCCC(F)(F)F)cc1 -US06967197B2,6,CCCc1ccc(-c2ccc([C@@]3(CC(=O)OC(C)(C)C)CCN(C(=O)OC(C)(C)C)CCS3(=O)=O)s2)cc1>>CCCc1ccc(-c2ccc([C@@]3(CC(=O)OC(C)(C)C)CCNCCS3(=O)=O)s2)cc1 -US08664216B2,1,CN1Cc2cc(Cl)ccc2-n2c(Br)nnc2C1.O=C1OC2(CCNCC2)c2ccccc21>>CN1Cc2cc(Cl)ccc2-n2c(nnc2N2CCC3(CC2)OC(=O)c2ccccc23)C1 -US20150225400A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCC(=O)c1ccc(F)c(Br)c1>>CCC(=O)c1ccc(F)c(B2OC(C)(C)C(C)(C)O2)c1 -US20110263571A1,2,CS(=O)(=O)c1cc(Br)ccc1C(=O)O.Cc1cnc(N2CCNCC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2)c(C)c1 -US20020015805A1,3,N#Cc1ccc(Br)cc1.OB(O)c1c(F)cc(CCC2OCCO2)cc1F>>N#Cc1ccc(-c2c(F)cc(CCC3OCCO3)cc2F)cc1 -US20070208005A1,9,CC(C)(C)OC(=O)N1CCc2ccc(CBr)cc2CC1.[C-]#N>>CC(C)(C)OC(=O)N1CCc2ccc(CC#N)cc2CC1 -US20090233956A1,1,COc1cc2c(-c3cc4c(C=O)ccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(C)c2cc1OC.NC1CC1>>COc1cc2c(-c3cc4c(CNC5CC5)ccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(C)c2cc1OC -US07897607B2,7,CNC(=O)c1c([N+](=O)[O-])c(C)nn1-c1c(Cl)cc(Cl)cc1Cl>>CNC(=O)c1c(N)c(C)nn1-c1c(Cl)cc(Cl)cc1Cl -US20050234065A1,1,COC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H]1CC[C@@H](OS(C)(=O)=O)CC1.[N-]=[N+]=[N-]>>COC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H]1CC[C@@H](N=[N+]=[N-])CC1 -US20050171181A1,9,OC1(c2ccc(CN3CCCC3)cc2)CC(CN2CCCC2)C1>>c1cc(C2CC(CN3CCCC3)C2)ccc1CN1CCCC1 -US06933305B2,2,COC(=O)c1ccc2c(c1)SCCCC2N.O=C(Cl)OCc1ccccc1>>COC(=O)c1ccc2c(c1)SCCCC2NC(=O)OCc1ccccc1 -US07576225B2,7,C[C@@H]1OC(OC(=O)c2ccccc2)[C@H](OC(=O)c2ccccc2)[C@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1>>C[C@@H]1OC(O)[C@H](OC(=O)c2ccccc2)[C@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1 -US08017786B2,7,O=C(O)C(=O)Cc1ccc(O)c(O)c1>>O=C(O)C(O)Cc1ccc(O)c(O)c1 -US08450243B2,6,CCOC(=O)c1cc2cc(F)cnc2n(C)c1=O>>Cn1c(=O)c(C(=O)O)cc2cc(F)cnc21 -US20150018377A1,1,CCOc1cccc(O)c1.O=[N+]([O-])c1ccc(F)cc1>>CCOc1cccc(Oc2ccc([N+](=O)[O-])cc2)c1 -US20050261177A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.N#Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1 -US20060148893A1,1,CCCNCC1CC1.N#Cc1ccc(F)cc1C(F)(F)F>>CCCN(CC1CC1)c1ccc(C#N)c(C(F)(F)F)c1 -US07888352B2,1,O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1.O=S(=O)(c1nccs1)C1CCNCC1>>O=S(=O)(c1nccs1)C1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1 -US05405865,7,CCOC(=O)c1ccoc1C(F)(F)F>>OCc1ccoc1C(F)(F)F -US08084474B2,2,Cc1cc(Cl)cc(C(=O)NC2(C)CS(=O)(=O)C2)c1N.O=C(Cl)c1cc(OCC(F)(F)F)nn1-c1ncccc1Cl>>Cc1cc(Cl)cc(C(=O)NC2(C)CS(=O)(=O)C2)c1NC(=O)c1cc(OCC(F)(F)F)nn1-c1ncccc1Cl -US20150045378A1,2,CO.O=C(O)CC(c1cccc(O)c1)C1CC1>>COC(=O)CC(c1cccc(O)c1)C1CC1 -US20100048537A1,1,NC(=O)c1ccc(F)c(Cl)c1.OC1CNCc2ccoc21>>NC(=O)c1ccc(OC2CNCc3ccoc32)c(Cl)c1 -US20040138286A1,1,CC(C)=O.Nc1ccc2[nH]ncc2c1>>CC(C)Nc1ccc2[nH]ncc2c1 -US20130123537A1,1,CI.N[C@H](CO)C(=O)N(Cc1ccccc1)C(c1ccccc1)(c1ccccc1)c1ccccc1>>COC[C@@H](N)C(=O)N(Cc1ccccc1)C(c1ccccc1)(c1ccccc1)c1ccccc1 -US08546377B2,7,CC(C)(C)OC(=O)N1CCN2c3ccccc3NC(=O)CC2C1>>CC(C)(C)OC(=O)N1CCN2c3ccccc3NCCC2C1 -US08669271B2,3,CC(C)OC(=O)N1CCC(C2Cc3cc(Br)ccc3O2)CC1.Cc1nc(Cl)ccc1B(O)O>>Cc1nc(Cl)ccc1-c1ccc2c(c1)CC(C1CCN(C(=O)OC(C)C)CC1)O2 -US20100172836A1,1,Brc1ccc(I)cn1.OCCOCCOCCO>>OCCOCCOCCOc1ccc(I)cn1 -US20150073139A1,6,CCOC(=O)c1sc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F>>O=C(O)c1sc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F -US04378314,6,COC(=O)C(CCC#N)N=[N+]=[N-]>>N#CCCC(N=[N+]=[N-])C(=O)O -US05668176,2,CCCc1cc(C(=O)O)ccc1OC(C(=O)NS(=O)(=O)c1ccc(C(C)C)cc1)c1ccc2c(c1)OCO2.NS(N)(=O)=O>>CCCc1cc(C(=O)NS(N)(=O)=O)ccc1OC(C(=O)NS(=O)(=O)c1ccc(C(C)C)cc1)c1ccc2c(c1)OCO2 -US20100311966A1,6,CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NC(=O)OCc1ccccc1>>CO[C@@H]1CNCC[C@@H]1NC(=O)OCc1ccccc1 -US05012007,7,CC(C)C(=O)c1ccccc1>>CC(C)C(O)c1ccccc1 -US20150112058A1,9,CC(=O)c1ccc(F)cc1Br.[NH4+]>>CC(=O)c1ccc(N)cc1Br -US20150284411A1,7,CCOC(=O)CC1CO[C@@H]2[C@H](O[Si](C)(C)C(C)(C)C)CO[C@H]12>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2C(CCO)CO[C@H]12 -US07368582B2,4,CC1(C)C=Cc2cc(CC(=O)NC3CCCc4ccccc43)ccc2O1.O=C(OO)c1cccc(Cl)c1>>CC1(C)Oc2ccc(CC(=O)NC3CCCc4ccccc43)cc2C2OC21 -US20080045521A1,2,COC(=O)[C@@H](N)Cc1ccc(C=O)cc1.O=C(O)c1c(Cl)cccc1Cl>>COC(=O)[C@H](Cc1ccc(C=O)cc1)NC(=O)c1c(Cl)cccc1Cl -US20140213586A1,1,COc1cc(N)cc(OC)c1.O=Cc1ccc(F)cc1>>COc1cc(N=Cc2ccc(F)cc2)cc(OC)c1 -US20030216432A1,1,CCCI.Cc1cc2c(cc1-c1cc(C=O)ccc1OC(F)(F)F)NC(=O)C2(C)C>>CCCN1C(=O)C(C)(C)c2cc(C)c(-c3cc(C=O)ccc3OC(F)(F)F)cc21 -US07517889B2,7,COc1nc(NCCc2ccc(C(F)(F)F)cc2F)cc(-c2cccc(CC#N)c2)n1>>COc1nc(NCCc2ccc(C(F)(F)F)cc2F)cc(-c2cccc(CCN)c2)n1 -US20090137804A1,1,CN(C)Cc1ccc(N)cc1C(F)(F)F.Nc1cc(Cl)ncn1>>CN(C)Cc1ccc(Nc2cc(N)ncn2)cc1C(F)(F)F -US20090233902A1,1,COc1ccc2[nH]c3c(c2c1)CC1(C)C(=O)N(CCBr)C(=O)N1C3c1cccc(O)c1.NC1CC1>>COc1ccc2[nH]c3c(c2c1)CC1(C)C(=O)N(CCNC2CC2)C(=O)N1C3c1cccc(O)c1 -US04355160,6,CCOC(=O)C(NC(=O)CCl)N(C(=O)CCl)c1cscn1>>O=C(CCl)NC(C(=O)O)N(C(=O)CCl)c1cscn1 -US20140057937A1,2,Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O.Cc1nn(-c2ccc(F)cc2)c2c1NCCC2>>Cc1nn(-c2ccc(F)cc2)c2c1N(C(=O)Cn1nc(C(F)(F)F)c(Cl)c1C)CCC2 -US07381728B2,3,COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(Br)cc1.Cc1csc(B(O)O)c1>>COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(-c2cc(C)cs2)cc1 -US20050154042A1,7,COC(=O)C[C@H](O)CC(=O)C=Cc1c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c(C(=O)N2CCCCC2)n1C(C)C>>COC(=O)C[C@H](O)C[C@H](O)C=Cc1c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c(C(=O)N2CCCCC2)n1C(C)C -US20090291988A1,7,O=C(c1ccc(Br)cc1)C(F)F>>OC(c1ccc(Br)cc1)C(F)F -US20150111811A1,8,CCC(C)/C=C(\C=C\C(C)O)C(C)(C)C>>CCC(C)/C=C(\C=C\C(C)=O)C(C)(C)C -US20050010068A1,3,Brc1ccccc1.C[Sn](C)(C)c1ccccc1>>c1ccc(-c2ccccc2)cc1 -US20070249670A1,2,C[C@@H](OCc1ccccc1)[C@H](NC(=O)c1ccc(F)cc1N)C(=O)OCc1ccccc1.Cc1cc(C)c(N=C=O)c(C)c1>>Cc1cc(C)c(NC(=O)Nc2cc(F)ccc2C(=O)N[C@H](C(=O)OCc2ccccc2)[C@@H](C)OCc2ccccc2)c(C)c1 -US20120289500A1,2,Cc1ccsc1-c1nn(N)c(=O)c2ccccc12.O=C(O)Cc1cc(F)cc(F)c1>>Cc1ccsc1-c1nn(NC(=O)Cc2cc(F)cc(F)c2)c(=O)c2ccccc12 -US20100249095A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1 -US20140323468A1,3,CC(C)(C)OC(=O)N1CCCc2cc(B3OC(C)(C)C(C)(C)O3)cnc21.Oc1cncc(Br)c1>>CC(C)(C)OC(=O)N1CCCc2cc(-c3cncc(O)c3)cnc21 -US20150266838A1,1,Clc1cc(Br)cc2nonc12.OC1CNC1>>OC1CN(c2cc(Br)cc3nonc23)C1 -US09062044B2,3,COC(=O)c1cc(F)ccc1B1OC(C)(C)C(C)(C)O1.Clc1ncccn1>>COC(=O)c1cc(F)ccc1-c1ncccn1 -USH0001992H1,6,CC(C)[C@H](C(=O)OC(C)(C)C)N(Cc1cccnc1)S(=O)(=O)c1ccc(Oc2ccc(Br)cc2)cc1>>CC(C)[C@H](C(=O)O)N(Cc1cccnc1)S(=O)(=O)c1ccc(Oc2ccc(Br)cc2)cc1 -US20110105509A1,4,CC#Cc1cc(S(C)(=O)=O)cc(Cl)c1N>>Cc1cc2cc(S(C)(=O)=O)cc(Cl)c2[nH]1 -US20070249594A1,1,CC(=O)c1ccc(B(O)O)cc1.O=S1(=O)NC2CCCN2c2ccc(O)cc21>>CC(=O)c1ccc(Oc2ccc3c(c2)S(=O)(=O)NC2CCCN32)cc1 -US04933355,2,CCOC(=O)C(=O)c1csc(N)n1.Cc1ccc(N=C=O)cc1>>CCOC(=O)C(=O)c1csc(NC(=O)Nc2ccc(C)cc2)n1 -US20090005353A1,2,CC(C)(C)N1C(=O)C(NCC(=O)O)=C(c2ccccc2)S1(=O)=O.Cc1cc(C)c(CC(C)O)c(C)c1>>Cc1cc(C)c(CC(C)OC(=O)CNC2=C(c3ccccc3)S(=O)(=O)N(C(C)(C)C)C2=O)c(C)c1 -US20140274926A1,2,CC(C)OC(=O)Cl.Nc1cnc2nc(-c3cc(NC(=O)N4CCCC4)ccc3Cl)oc2c1>>CC(C)OC(=O)Nc1cnc2nc(-c3cc(NC(=O)N4CCCC4)ccc3Cl)oc2c1 -US20110212930A1,9,COC(=O)C(C(=O)c1cc(C(F)(F)F)nn1-c1ccc(OC)cc1)c1ccc(-n2ccccc2=O)cc1F>>COc1ccc(-n2nc(C(F)(F)F)cc2C(=O)Cc2ccc(-n3ccccc3=O)cc2F)cc1 -US08410107B2,3,CCc1ccc(B(O)O)cc1.O=C(Nc1cnc(OCC(F)(F)F)c(Br)c1)c1cccnn1>>CCc1ccc(-c2cc(NC(=O)c3cccnn3)cnc2OCC(F)(F)F)cc1 -US20060199857A1,1,COC(=O)C(Cl)Cc1ccc(CCO)cc1.Oc1ccc(OCc2ccccc2)cc1>>COC(=O)C(Cl)Cc1ccc(CCOc2ccc(OCc3ccccc3)cc2)cc1 -US05030654,6,COCCOC[C@H](CC1(C(=O)N[C@H]2CC[C@@H](C(=O)OCc3ccccc3)CC2)CCCC1)C(=O)Oc1ccc2c(c1)CCC2>>COCCOC[C@H](CC1(C(=O)N[C@H]2CC[C@@H](C(=O)O)CC2)CCCC1)C(=O)Oc1ccc2c(c1)CCC2 -US20140194408A1,7,Cn1cc(-c2ccnc(N3CCn4c5c(c(F)c4C3=O)CCCC5)c2C=O)cc(Nc2cc3n(n2)CCN(C2COC2)C3)c1=O>>Cn1cc(-c2ccnc(N3CCn4c5c(c(F)c4C3=O)CCCC5)c2CO)cc(Nc2cc3n(n2)CCN(C2COC2)C3)c1=O -US20060111353A1,7,CCOC(=O)/C(=C/CC1CCCC1)c1ccc(S(C)(=O)=O)s1>>CS(=O)(=O)c1ccc(/C(=C\CC2CCCC2)CO)s1 -US20090286848A1,6,COC(=O)C(c1ccc(C=CC(=O)Nc2ccccc2NC(=O)OC(C)(C)C)cc1)N1CCC(O)C1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)/C=C/c1ccc(C(C(=O)O)N2CC[C@H](O)C2)cc1 -US20090270417A1,6,COCCCOc1cc(O[C@@H](C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C(=O)OC2CCOCC2)C2CC2)C(C)C)ccc1OC>>COCCCOc1cc(O[C@H](C[C@@H]2CNC[C@H]2CN(C(=O)OC2CCOCC2)C2CC2)C(C)C)ccc1OC -US20110257243A1,3,CC(C)(C)OC(=O)N1CC[C@H](C=O)C1.[Mg+]C1CC1>>CC(C)(C)OC(=O)N1CC[C@H]([C@@H](O)C2CC2)C1 -US20110257243A1,3,CC(C)(C)OC(=O)N1CC[C@H](C=O)C1.[Mg+]C1CC1>>CC(C)(C)OC(=O)N1CC[C@H]([C@H](O)C2CC2)C1 -US07868008B2,9,COc1cc(OC)c2c(c1Br)CN(C(C)c1ccc(Cl)cc1)C2=O>>COc1cc2c(c(OC)c1)C(=O)N(C(C)c1ccc(Cl)cc1)C2 -US20090111862A1,7,COc1cc(C=O)ccc1S(=O)(=O)N(C)C>>COc1cc(CO)ccc1S(=O)(=O)N(C)C -US04829067,9,O=C(O)c1cc(Cl)cc2cc(-c3ccccc3)oc12>>O=C(O)c1cccc2cc(-c3ccccc3)oc12 -US07875700B2,1,C=CCC(=O)OCC.COCCOCCOCCO>>CCOC(=O)CCCOCCOCCOCCOC -US20140200227A1,2,CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(N)cnc3c2ccn3S(=O)(=O)c2ccccc2)C1.O=C(O)c1csc(-c2c(F)cccc2F)n1>>CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(NC(=O)c3csc(-c4c(F)cccc4F)n3)cnc3c2ccn3S(=O)(=O)c2ccccc2)C1 -US08399459B2,6,CC(C)(C)OC(=O)n1c(-c2cccc(C3(C)COCC(N)=N3)c2)cc2ccc(Cl)cc21>>CC1(c2cccc(-c3cc4ccc(Cl)cc4[nH]3)c2)COCC(N)=N1 -US20050153962A1,6,COC(=O)c1nc(Nc2ccc(Cl)c(OC)c2)sc1C>>COc1cc(Nc2nc(C(=O)O)c(C)s2)ccc1Cl -US20110257151A1,2,CC(C)(C)OC(=O)N1CC(N)C1.COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(C(=O)O)c1)N2>>COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(C(=O)NC3CN(C(=O)OC(C)(C)C)C3)c1)N2 -US04518603,7,CN(C)CCCN(c1ccccc1C(=O)c1ccccc1)c1ncccc1[N+](=O)[O-]>>CN(C)CCCN(c1ccccc1C(=O)c1ccccc1)c1ncccc1N -US04372970,6,CCOC(=O)c1cc2cc(CC#N)ccc2o1>>N#CCc1ccc2oc(C(=O)O)cc2c1 -US07595327B2,1,CCOC(=O)C1CNCCC1NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1.OCCBr>>CCOC(=O)C1CN(CCO)CCC1NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 -US20040122244A1,7,COC1=C(OC)C(=O)C(Cc2cccc(C(=O)Nc3ccc(N4CCOCC4)cc3)c2OC(C)=O)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2cccc(C(=O)Nc3ccc(N4CCOCC4)cc3)c2O)=C(C)C1=O -US20020040048A1,2,NNC(=O)[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1S(=O)(=O)c1ccc2ccccc2c1.O=C(Cl)CCCBr>>O=C(CCCBr)NNC(=O)[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1S(=O)(=O)c1ccc2ccccc2c1 -US09133224B2,2,CCOC(=O)c1nc(Br)ccc1N.CN>>CNC(=O)c1nc(Br)ccc1N -US07049312B1,3,O=C1COc2ccccc2N1.O=Cc1ccc[nH]1>>O=C1Nc2ccccc2OC1=Cc1ccc[nH]1 -US03987199,6,CC(=O)Nc1ccc(S(N)(=O)=O)cc1[N+](=O)[O-]>>Nc1ccc(S(N)(=O)=O)cc1[N+](=O)[O-] -US20130023541A1,2,CO.O=C(Cl)c1cccnc1Cl>>COC(=O)c1cccnc1Cl -US07345050B2,3,Brc1nccs1.CON(C)C(=O)c1ccc(Br)cc1>>O=C(c1ccc(Br)cc1)c1nccs1 -US20130345222A1,1,CC(C)(C)[Si](C)(C)Oc1cccc(C=O)c1.CCOC(=O)C1(N)CC1>>CCOC(=O)C1(NCc2cccc(O[Si](C)(C)C(C)(C)C)c2)CC1 -US20050130941A1,6,CC(C)(C)OC(=O)NN(CC1CCCCC1)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)C(F)(F)F>>CC(C)(C)OC(=O)NN(CC1CCCCC1)C[C@@H](O)[C@@H](N)Cc1ccccc1 -US06281363B1,1,C=O.CC(C)C[C@@H](C(=O)NN1C(=O)NC2(CCNCC2)C1=O)[C@H](CCCc1ccccc1)C(=O)OC(C)(C)C>>CC(C)C[C@@H](C(=O)NN1C(=O)NC2(CCN(C)CC2)C1=O)[C@H](CCCc1ccccc1)C(=O)OC(C)(C)C -US08618162B2,1,C=C(C)CCl.Oc1ccccc1S>>C=C(C)CSc1ccccc1O -US20130079320A1,6,CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNC(=O)OC(C)(C)C)c(Cl)c2)CC1>>CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CN)c(Cl)c2)CC1 -US08183262B2,3,Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2ccnc(Cl)c2)c1.O=[N+]([O-])c1cccc(B(O)O)c1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2ccnc(-c3cccc([N+](=O)[O-])c3)c2)c1 -US20150141400A1,5,CCOC(=O)c1cc(OC(F)(F)F)c(C=O)c(Cl)c1N.OCCO>>CCOC(=O)c1cc(OC(F)(F)F)c(C2OCCO2)c(Cl)c1N -US05616582,1,COCCBr.Cc1cccc(Nc2ncnc3ccc(N)cc23)c1>>COCCNc1ccc2ncnc(Nc3cccc(C)c3)c2c1 -US20120122942A1,7,CC(C)CCC=Cc1cc2cc(Cl)ccc2[nH]1>>CC(C)CCCCc1cc2cc(Cl)ccc2[nH]1 -US20120184531A1,2,CC(C)(C)OC(=O)N1CCc2oc3c(CO)cc(Br)cc3c2C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCc2oc3c(COS(C)(=O)=O)cc(Br)cc3c2C1 -US20110275797A1,6,COC(=O)c1cncc(-c2ccoc2)c1>>O=C(O)c1cncc(-c2ccoc2)c1 -US04734419,1,CCOC(=O)CBr.O=c1[nH]c2cc(Cl)ccc2c(=O)n1Cc1ccc(Br)cc1F>>CCOC(=O)Cn1c(=O)n(Cc2ccc(Br)cc2F)c(=O)c2ccc(Cl)cc21 -US20080200483A1,2,N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O.O=C(Cl)c1ccno1>>O=C(N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O)c1ccno1 -US08327467B2,3,Brc1ccsc1.C=Cc1ccc(C(=O)OC(C)(C)C)c(Nc2ccc(F)cc2)c1>>CC(C)(C)OC(=O)c1ccc(/C=C/c2ccsc2)cc1Nc1ccc(F)cc1 -US08354431B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc2c(OCc3ccccc3)cccc2[nH]1>>CCOC(=O)c1cc2c(OCc3ccccc3)cccc2n1C(=O)OC(C)(C)C -US20040224961A1,1,C[C@@H](N)CO.Nc1nc2nc(SCc3ccccc3)nc(Cl)c2s1>>C[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(N)sc12 -US20070111988A1,6,COC(=O)c1cc(-c2ccc3cc(OC)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)ccc1OCc1ccccc1>>COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(OCc4ccccc4)c(C(=O)O)c3)ccc2c1 -US06573377B1,1,COc1ccc(CNc2nc(Cl)nc(Cl)n2)cc1.OC1CNC1>>COc1ccc(CNc2nc(Cl)nc(N3CC(O)C3)n2)cc1 -US07462639B2,2,CC(=O)Cl.Cc1[nH]nc(-c2nc3cc4c(cc3[nH]2)C(C)(C)C(=O)N4)c1N>>CC(=O)Nc1c(-c2nc3cc4c(cc3[nH]2)C(C)(C)C(=O)N4)n[nH]c1C -US20090075964A1,7,C=C[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C>>C=C[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C -US20110178053A1,2,COc1cc2c(cn1)[nH]c1ncc(F)cc12.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc2c3cc(F)cnc3n(S(=O)(=O)c3ccc(C)cc3)c2cn1 -US20120289500A1,2,Nn1nc(N2CCOCC2)c2ccccc2c1=O.O=C(O)Cc1ccccc1[N+](=O)[O-]>>O=C(Cc1ccccc1[N+](=O)[O-])Nn1nc(N2CCOCC2)c2ccccc2c1=O -US20070299068A1,1,CCn1c(C#Cc2ccc(NC(=O)NCCCl)cc2)c(C#N)c2ccc(OC)cc21>>CCn1c(C#Cc2ccc(N3CCNC3=O)cc2)c(C#N)c2ccc(OC)cc21 -US04008272,1,NCCN.O=[N+]([O-])c1ccc(Cl)c(Cl)c1>>NCCNc1ccc([N+](=O)[O-])cc1Cl -US05616614,2,CCCN=C=O.COC(=O)C(CN)c1cccc2ccccc12>>CCCNC(=O)NCC(C(=O)OC)c1cccc2ccccc12 -US20100261757A1,1,CC(C)C=O.COc1ccc(CSCCNCc2ccc(Cl)nc2)cc1>>COc1ccc(CSCCN(Cc2ccc(Cl)nc2)CC(C)C)cc1 -US20070254873A1,1,CCN.CN(C)CCCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(C=O)c4)cc23)CC1>>CCNCc1cccc(-c2cc(C(N)=O)c3[nH]cc(C4CCN(S(=O)(=O)CCCN(C)C)CC4)c3c2)c1 -US20090181929A1,3,C=CC(=O)OC.CCN(CC1CCCC1)c1ncc(Br)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1>>CCN(CC1CCCC1)c1ncc(/C=C/C(=O)OC)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1 -US20080221188A1,7,Cc1cc(Br)ccc1C(=O)O>>Cc1cc(Br)ccc1CO -US04548639,2,C1CC2(CCN1)OCCO2.O=C(Cl)C(Cl)Cl>>O=C(C(Cl)Cl)N1CCC2(CC1)OCCO2 -US20070197512A1,2,Nc1cc(Cl)ccc1O.O=C(Cl)C(Cl)c1ccccc1>>O=C(Nc1cc(Cl)ccc1O)C(Cl)c1ccccc1 -US20130053375A1,1,C=CCOc1ccc(C)c(Nc2ccnc(Cl)n2)c1.Nc1cccc(C(=O)O)c1>>C=CCOc1ccc(C)c(Nc2ccnc(Nc3cccc(C(=O)O)c3)n2)c1 -US05089492,2,CC(C)[C@H](N=O)C(=O)O.COC(=O)[C@@H](N)CC(C)C>>COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N=O)C(C)C -US20140323488A1,1,CNc1c(C)cc(C)cc1C.Clc1nc(Cl)nc(Cl)n1>>Cc1cc(C)c(N(C)c2nc(Cl)nc(Cl)n2)c(C)c1 -US07423012B2,2,CC(C)(C)OC(=O)NC1CCC(C(=O)O)CC1.CNOC>>CON(C)C(=O)C1CCC(NC(=O)OC(C)(C)C)CC1 -US06693123B2,7,O=C(O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1>>Nc1ccc(-c2ccc(C(=O)O)cc2)cc1 -US20140228361A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cc2c(cn1)CNCC2>>CC(C)(C)OC(=O)N1CCc2ccncc2C1 -US07932281B2,6,CCCN(CCC)CCCCc1nc2ccc(CN3C(=O)c4ccccc4C3=O)cc2n1C>>CCCN(CCC)CCCCc1nc2ccc(CN)cc2n1C -US20090203674A1,1,CCC#CCO.Fc1c(Cl)ncnc1Cl>>CCC#CCOc1ncnc(Cl)c1F -US06706725B1,8,CC/C(=C\CO)c1ccc(COc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)s1>>CC/C(=C\C=O)c1ccc(COc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)s1 -US05968967,1,CCOC(=O)c1c(-c2ccc(F)cc2)n(C)n(-c2ccc(C#N)cc2)c1=O.CN1CCNCC1>>CCOC(=O)c1c(-c2ccc(N3CCN(C)CC3)cc2)n(C)n(-c2ccc(C#N)cc2)c1=O -US07354942B2,2,CC(N)c1ccc(F)cc1.CCCN(c1cc(COCC(C)(Cc2ccccc2)NC(=O)OC(C)(C)C)cc(C(=O)O)n1)S(C)(=O)=O>>CCCN(c1cc(COCC(C)(Cc2ccccc2)NC(=O)OC(C)(C)C)cc(C(=O)NC(C)c2ccc(F)cc2)n1)S(C)(=O)=O -US20090281306A1,1,CCOC(=O)N1CCC(=O)CC1.Nc1cccnc1Cl>>CCOC(=O)N1CCC(Nc2cccnc2Cl)CC1 -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccccc1>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1-c1ccccc1 -US09150555B2,6,CCOC(=O)c1nnn(-c2ccc(C(F)(F)F)cn2)c1C>>Cc1c(C(=O)O)nnn1-c1ccc(C(F)(F)F)cn1 -US20130172560A1,7,O=C(CCl)c1ccc(Br)cc1>>O[C@@H](CCl)c1ccc(Br)cc1 -US20150252072A1,9,CC(C)[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N1c2ncccc2C[C@H]1CN=[N+]=[N-]>>CC(C)[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N1c2ncccc2C[C@H]1CN -US20110144105A1,2,CC(C)CC(c1ccc(S(C)(=O)=O)cc1)c1cc2cc(C(=O)O)cnc2[nH]1.CC(C)N>>CC(C)CC(c1ccc(S(C)(=O)=O)cc1)c1cc2cc(C(=O)NC(C)C)cnc2[nH]1 -US20030069292A1,1,Clc1ncccn1.Fc1ccc(Oc2ccc(-c3cc[nH]n3)cc2)cc1>>Fc1ccc(Oc2ccc(-c3ccn(-c4ncccn4)n3)cc2)cc1 -US06395731B1,2,CC(C)(C)OC(=O)Nc1nc(-c2ccc(C(=O)O)cc2)c[nH]1.O=S(=O)(c1ccc2cc(Br)ccc2c1)N1CCNCC1>>CC(C)(C)OC(=O)Nc1nc(-c2ccc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Br)ccc5c4)CC3)cc2)c[nH]1 -US05608056,2,C=CCOC(=O)N1C[C@@H](C(C)(C)C)C[C@@]1(CCCO)O[SiH](C)C.CS(=O)(=O)Cl>>C=CCOC(=O)N1C[C@@H](C(C)(C)C)C[C@@]1(CCCOS(C)(=O)=O)O[SiH](C)C -US03965100,1,BrCc1ccccc1.O=c1c2c(nc3c(O)cccn13)CCC2>>O=c1c2c(nc3c(OCc4ccccc4)cccn13)CCC2 -US04397847,2,CCOC(C)OC(C)(C)C(F)(F)CCO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(C)OC(C)(C)C(F)(F)CCOS(=O)(=O)c1ccc(C)cc1 -US04260633,1,CC(C)[C@H](Br)C(=O)O.Nc1ccc(C(F)(F)F)cc1>>CC(C)[C@H](Nc1ccc(C(F)(F)F)cc1)C(=O)O -US20090082434A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3c(Br)cccc3O2)cc1.OB(O)c1ccccc1C(F)(F)F>>Cc1ccc(S(=O)(=O)OCC2Cc3c(cccc3-c3ccccc3C(F)(F)F)O2)cc1 -US20080234301A1,2,CCOc1cc(-c2cnc[nH]c2=O)ccc1N.Cc1ccccc1N=C=O>>CCOc1cc(-c2cnc[nH]c2=O)ccc1NC(=O)Nc1ccccc1C -US20070123532A1,7,COC[C@@H]1CN(CCN2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3ccc(C)c(NCN4C(=O)CCC4=O)c3)C2)CCO1>>COC[C@@H]1CN(CCN2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3ccc(C)c(NCN4C(=O)CCC4O)c3)C2)CCO1 -US20090048323A1,6,CN(C)C(CCc1ccccc1)C1CCC2(CC1)OCCO2>>CN(C)C(CCc1ccccc1)C1CCC(=O)CC1 -US08507549B2,7,Oc1ccc(C2=Cc3ccc(O)cc3OC2)cc1>>Oc1ccc(C2COc3cc(O)ccc3C2)cc1 -US05663416,6,COC(=O)C1(c2ccc3c(c2)CCCC3)CCC1>>O=C(O)C1(c2ccc3c(c2)CCCC3)CCC1 -US20040048915A1,1,Brc1cccc2cc[nH]c12.CCI>>CCn1ccc2cccc(Br)c21 -US20140011777A1,1,CC(C)(C)[Si](C)(C)OC1(CCCN)CCCCC1.O=[N+]([O-])c1cnc2ccccc2c1Cl>>CC(C)(C)[Si](C)(C)OC1(CCCNc2c([N+](=O)[O-])cnc3ccccc23)CCCCC1 -US20040142850A1,9,CCOC(=O)N(Cc1ccccc1Cl)c1c([N+](=O)[O-])cc(Br)cc1C(F)(F)F.[C-]#N>>CCOC(=O)N(Cc1ccccc1Cl)c1c([N+](=O)[O-])cc(C#N)cc1C(F)(F)F -US20100160424A1,6,COC(=O)NCCOC(c1cccc(Cl)c1)c1cccc(C(=O)OC)c1>>COC(=O)NCCOC(c1cccc(Cl)c1)c1cccc(C(=O)O)c1 -US20110294780A1,1,CN1CCN(CCO)CC1.COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)NC4=O)ccc32)c(C(F)(F)F)c1>>COc1ccc(Cn2ncc3cc(/C=C4\SC(=O)N(CCN5CCN(C)CC5)C4=O)ccc32)c(C(F)(F)F)c1 -US07153854B2,7,CCOC(=O)CC(=O)Cc1c(C)nn2c(Cl)ccc2c1-c1ccc(F)cc1>>CCOC(=O)CC(O)Cc1c(C)nn2c(Cl)ccc2c1-c1ccc(F)cc1 -US20150152127A1,1,C=CCOc1ccc(CCl)cc1.CN(C)C1=N[C@H]2[C@H](O[C@H]([C@@H](O)C(F)(F)F)[C@@H](O)[C@@H]2O)S1>>C=CCOc1ccc(CO[C@H]([C@H]2O[C@@H]3SC(N(C)C)=N[C@@H]3[C@@H](O)[C@@H]2O)C(F)(F)F)cc1 -US05866583,1,CNOC.O=C(Cl)N1CCc2ccccc2C1>>CON(C)C(=O)N1CCc2ccccc2C1 -US20070123495A1,6,COC(=O)COc1ccc2cc(-c3ccc(-c4ccccc4)n3Cc3ccc(C(F)(F)F)cc3)ccc2c1>>O=C(O)COc1ccc2cc(-c3ccc(-c4ccccc4)n3Cc3ccc(C(F)(F)F)cc3)ccc2c1 -US06127391,2,CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc2ccccc2c1)C(=O)O.CN[C@H](Cc1ccccc1)C(=O)NCC(F)(F)F>>CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)NCC(F)(F)F -US20080045507A1,3,CC(C)N1CCCN(C(=O)c2ccc(C=O)cc2)CC1.[Mg+]C1CCCCC1>>CC(C)N1CCCN(C(=O)c2ccc(C(O)C3CCCCC3)cc2)CC1 -US08501782B2,2,CC(C)(N)CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1.O=C(Cl)Oc1ccccc1>>CC(C)(CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)NC(=O)Oc1ccccc1 -US20150057265A1,1,C[C@H]1CNC[C@@H](NC(=O)OC(C)(C)C)[C@]1(C)O.O=[N+]([O-])c1cnccc1Cl>>C[C@H]1CN(c2ccncc2[N+](=O)[O-])C[C@@H](NC(=O)OC(C)(C)C)C1(C)O -US20080090805A1,7,O=C(O)c1ccc(Sc2ccc(Cl)cc2C(=O)O)c([N+](=O)[O-])c1>>Nc1cc(C(=O)O)ccc1Sc1ccc(Cl)cc1C(=O)O -US20090298827A1,6,COCOc1ccc(-c2ccc3c(c2CNc2ccccc2OC)C(C)=CC(C)(C)N3)c(OC)c1>>COc1ccccc1NCc1c(-c2ccc(O)cc2OC)ccc2c1C(C)=CC(C)(C)N2 -US07202251B2,7,CCOC(=O)c1ccc(Nc2ccccc2[N+](=O)[O-])cc1>>CCOC(=O)c1ccc(Nc2ccccc2N)cc1 -US20110124875A1,6,COCCS(=O)(=O)c1ccccc1CNC(=O)OC(C)(C)C>>COCCS(=O)(=O)c1ccccc1CN -US05180671,6,CCOC(=O)[C@H]1[C@@H](C=C(Cl)Cl)C1(C)C>>CC1(C)C(C=C(Cl)Cl)C1C(=O)O -US20070219210A1,2,CC(C)(C)N.CC(C)(C)OC(=O)Nc1ccc(-c2cc(C(=O)O)nn2-c2cnccn2)nc1>>CC(C)(C)NC(=O)c1cc(-c2ccc(NC(=O)OC(C)(C)C)cn2)n(-c2cnccn2)n1 -US08940756B2,7,O=[N+]([O-])c1ccc(F)c(CN2CCCC2)c1>>Nc1ccc(F)c(CN2CCCC2)c1 -US20120270865A2,7,Cc1c(C(=O)C2CCCCC2)oc2c(F)cc(F)cc12>>Cc1c(C(O)C2CCCCC2)oc2c(F)cc(F)cc12 -US20130109704A1,4,CC(=O)CC(C)=O.Cn1cnc2c(Nc3ccccc3)nc(NN)nc21>>Cc1cc(C)n(-c2nc(Nc3ccccc3)c3ncn(C)c3n2)n1 -US20040023974A1,2,CC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CCCCCNC(=O)[C@@H](N)Cc1ccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)cc1>>CCCCCNC(=O)[C@H](Cc1ccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(C)=O -US20020193385A1,7,Cc1ccc([N+](=O)[O-])cc1-c1cccnc1>>Cc1ccc(N)cc1-c1cccnc1 -US20020156081A1,6,CN1CCN(C2CCC(n3nc(-c4ccc(CNC(=O)OC(C)(C)C)cc4)c4c(N)ncnc43)CC2)CC1>>CN1CCN(C2CCC(n3nc(-c4ccc(CN)cc4)c4c(N)ncnc43)CC2)CC1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nccn4CCC)cc2)CCN3CCC)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nccn4CCC)cc2)CCN3CCC)cc1 -US20110112077A1,9,CC(C)(C)OC(=O)N1CCN(c2ccc3oc(C(N)=O)cc3c2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc3oc(C#N)cc3c2)CC1 -US20070027173A1,1,CS(=O)(=O)OCC1CCNC1.O=C(c1c[nH]c2cc(Cl)ccc12)N1CCC2(CC1)OCc1ccccc12>>O=C(c1cn(CC2CCNC2)c2cc(Cl)ccc12)N1CCC2(CC1)OCc1ccccc12 -US06368608B1,3,C#CC(O)c1ccc2c(c1)C(C)(C)CCC2(C)C.COC(=O)c1cc(I)cn1C(=O)OC(C)(C)C>>COC(=O)c1cc(C#CC(O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cn1C(=O)OC(C)(C)C -US20090286792A1,1,CNC(=O)c1ccc(C2(O)CCC(=O)CC2)nc1.N[C@H]1CCN(C(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C1>>CNC(=O)c1ccc(C2(O)CCC(N[C@H]3CCN(C(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)nc1 -US20080056987A1,1,CCOC(=O)c1cnc2ccc3c(c2c1Cl)CCS3(=O)=O.NCCCO>>CCOC(=O)c1cnc2ccc3c(c2c1NCCCO)CCS3(=O)=O -US20090275606A1,1,Nc1ccc(Br)cc1F.O=C(O)c1c(Cl)cc(=O)n2c1CCC2>>O=C(O)c1c(Nc2ccc(Br)cc2F)cc(=O)n2c1CCC2 -US20060025433A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1cccnc1>>CC(C)(C)OC(=O)NCc1cccnc1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CC(C)S(=O)(=O)c1ccc(F)c(Br)c1>>CC(C)S(=O)(=O)c1ccc(F)c(C#Cc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)c1 -US08063094B2,6,CC(C)(C)OC(=O)NCCCc1c(C(=O)O)[nH]c2ccc(-c3ccccc3F)cc12>>NCCCc1c(C(=O)O)[nH]c2ccc(-c3ccccc3F)cc12 -US20120010241A1,1,CC(C)(C)OC(=O)NCC(=O)O.Cc1nn(-c2ccc(C(N)=O)c(N[C@@H]3CC[C@@H](O)CC3)c2)c2cccc(-c3cnc4ccccc4c3)c12>>Cc1nn(-c2ccc(C(N)=O)c(N[C@@H]3CC[C@@H](OC(=O)CNC(=O)OC(C)(C)C)CC3)c2)c2cccc(-c3cnc4ccccc4c3)c12 -US07173043B2,1,BrCCCCOc1ccc2c(-c3ccc(Br)cc3)csc2c1.CCNCCO>>CCN(CCO)CCCCOc1ccc2c(-c3ccc(Br)cc3)csc2c1 -US20120165329A1,3,CN(C)C=O.Clc1ccc(CNc2ccc(Br)cn2)cc1>>O=Cc1ccc(NCc2ccc(Cl)cc2)nc1 -US20040220191A1,3,CN(C)C1CCN(c2ccc(NC(=O)N3CC=C(B4OC(C)(C)C(C)(C)O4)CC3)cc2)C1.CSc1cccc(Br)c1>>CSc1cccc(C2=CCN(C(=O)Nc3ccc(N4CCC(N(C)C)C4)cc3)CC2)c1 -US20120077812A1,1,Brc1ccc(Br)nc1.CC(C)(C)OC(=O)N1CCC(CO)CC1>>CC(C)(C)OC(=O)N1CCC(COc2ccc(Br)cn2)CC1 -US04402970,1,Cc1c(C(=O)c2ccccc2)c(NC(=O)CI)cn1C.NO>>Cc1c(C(=O)c2ccccc2)c(NC(=O)CNO)cn1C -US07323587B2,2,NS(=O)(=O)C(F)(F)F.O=C(O)C=Cc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1>>O=C(C=Cc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1)NS(=O)(=O)C(F)(F)F -US20130012504A1,6,Cc1cc(NC(=O)C(F)(F)F)ccc1C#CCCCO>>Cc1cc(N)ccc1C#CCCCO -US09051532B1,3,CC1=CC(C)C(C=O)CC1.CC[Mg+]>>CCC(O)C1CCC(C)=CC1C -US20100075978A1,2,Cc1cccc(N2CCN(CCN)CC2)n1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1>>Cc1cccc(N2CCN(CCNC(=O)c3ccc(S(=O)(=O)Nc4ccccc4Oc4ccc(Cl)cc4Cl)cc3)CC2)n1 -US20090239928A1,2,CC(C)(C)OC(=O)N1CC[C@H](N)C1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CC(C)(C)OC(=O)N1CC[C@H](NS(=O)(=O)c2ccc([N+](=O)[O-])cc2)C1 -US20020128262A1,2,CNc1ccccc1C(C)=O.O=C(Br)CBr>>CC(=O)c1ccccc1N(C)C(=O)CBr -US06855711B1,1,Oc1ccc(CCl)c2cccnc12.c1c[nH]cn1>>Oc1ccc(Cn2ccnc2)c2cccnc12 -US07135478B2,1,CC1CCNCC1.Cc1cc2c(CCl)c(CO)c(Cl)nc2cc1Cl>>Cc1cc2c(CN3CCC(C)CC3)c(CO)c(Cl)nc2cc1Cl -US20120022030A1,1,CN1CCNCC1.N#Cc1cc(Br)ccc1F>>CN1CCN(c2ccc(Br)cc2C#N)CC1 -US20140363452A1,7,N#CC1(c2ccccc2)CC1>>NCC1(c2ccccc2)CC1 -US06117893,1,COC(=O)CBr.c1ccc2c(c1)CCN2>>COC(=O)CN1CCc2ccccc21 -US20050107374A1,1,Cc1cccc(C)c1Oc1nc2ccccc2[nH]1.Clc1ccnc(Cl)n1>>Cc1cccc(C)c1Oc1nc2ccccc2n1-c1ccnc(Cl)n1 -US20130005707A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1noc2ccc(Br)cc12>>CC(C)(C)OC(=O)Nc1noc2ccc(Br)cc12 -US20020028835A1,1,NC[C@H](O)c1ccc(O)c(NS(=O)(=O)c2ccccc2)c1.O=C1CCN(c2ccc(CC3SC(=O)NC3=O)cc2)CC1>>O=C1NC(=O)C(Cc2ccc(N3CCC(NC[C@H](O)c4ccc(O)c(NS(=O)(=O)c5ccccc5)c4)CC3)cc2)S1 -US20100234351A1,1,BrCCOCc1ccccc1.CC1(C)OCC(CO)O1>>CC1(C)OCC(COCCOCc2ccccc2)O1 -US04686221,1,N#Cc1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O.ON1CCNCC1>>N#Cc1cn(C2CC2)c2c(F)c(N3CCN(O)CC3)c(F)cc2c1=O -US04661636,6,COc1ccc(C(C)(C)C)cc1S(=O)(=O)N=CN(C)C>>CN(C)C=NS(=O)(=O)c1cc(C(C)(C)C)ccc1O -US20140018345A1,1,CSCCCN.Cc1c(Br)cn2nc(Cl)nc2c1-c1cccc(C(F)(F)F)c1>>CSCCCNc1nc2c(-c3cccc(C(F)(F)F)c3)c(C)c(Br)cn2n1 -US20090291940A1,1,CNC.Clc1cc(Cl)nc(Cl)n1>>CN(C)c1cc(Cl)nc(Cl)n1 -US20100143299A1,3,CC(C)Oc1ncnc2ccc(Br)cc12.CNC(=O)c1ccc(B(O)O)cc1>>CNC(=O)c1ccc(-c2ccc3ncnc(OC(C)C)c3c2)cc1 -US20090137773A1,1,ClCC1CO1.FC(F)(F)C(F)(CCS)C(F)(F)F>>FC(F)(F)C(F)(CCSCC1CO1)C(F)(F)F -US05374634,2,COc1ccc(C(c2ccc(OC)cc2)c2cnccc2C(=O)Cl)cc1.NC12CC3CC(CC1C3)C2>>COc1ccc(C(c2ccc(OC)cc2)c2cnccc2C(=O)NC23CC4CC(CC2C4)C3)cc1 -US06166006,8,Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(-c4ccccn4)cc2)CCO3)cc1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(-c4cccc[n+]4[O-])cc2)CCO3)cc1 -US20100075952A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCC1)CCC2.O=C1Cc2c(Br)cccc2N1>>Cc1c(C=C2C(=O)Nc3cccc(Br)c32)[nH]c2c1C(=O)N(CCN1CCCC1)CCC2 -US07544812B2,1,CCI.CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3ccc(C(F)(F)F)cc3)C(=O)N2)cc1)Oc1ccccc1>>CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3ccc(C(F)(F)F)cc3)C(=O)N2CC)cc1)Oc1ccccc1 -US20150105388A1,2,O=C(O)c1cc(-c2cc(Br)cc(OC(F)(F)F)c2)n(-c2ccnc(C(F)(F)F)c2)n1.O=C1CNCCN1>>O=C1CN(C(=O)c2cc(-c3cc(Br)cc(OC(F)(F)F)c3)n(-c3ccnc(C(F)(F)F)c3)n2)CCN1 -US20110077399A1,2,CC(C)(C)c1ccc(CN)cc1.COc1ccc(/C=C/c2nc(-c3ccc(Cl)cc3Cl)cn2CC(=O)O)cc1>>COc1ccc(/C=C/c2nc(-c3ccc(Cl)cc3Cl)cn2CC(=O)NCc2ccc(C(C)(C)C)cc2)cc1 -US20090226398A1,1,ClCc1ccc(Cl)nc1.Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F>>Fc1cccc(-c2nc3cnn(Cc4ccc(Cl)nc4)cc-3n2)c1F -US06255496B1,1,CCCCCCCCCCCCN(C)CCO.O=C(c1ccccc1O)C(F)(F)F>>CCCCCCCCCCCCN(C)CCOc1ccccc1C(=O)C(F)(F)F -US09108856B2,1,CC1CCCC(N2CCCC2)C1.CCI>>CC[N+]1(C2CCCC(C)C2)CCCC1 -US08765730B2,1,C=CCC(CC(=O)c1ccc(=O)[nH]c1)c1ccc(Br)cc1.CI>>C=CCC(CC(=O)c1ccc(=O)n(C)c1)c1ccc(Br)cc1 -US08198295B2,2,CC(C)N[C@@H](C)COC(=O)c1ccc([N+](=O)[O-])cc1.CCOc1cc2c(cc1OC)C(c1ccc(C(=O)Cl)cc1)=N[C@@H]1CCN(C)C[C@H]21>>CCOc1cc2c(cc1OC)C(c1ccc(C(=O)N(C(C)C)[C@@H](C)COC(=O)c3ccc([N+](=O)[O-])cc3)cc1)=N[C@@H]1CCN(C)C[C@H]21 -US06620829B2,3,CCOC(=O)CC#N.C[C@@H]1CC(=O)C[C@H]1C>>CCOC(=O)C(C#N)=C1C[C@@H](C)[C@H](C)C1 -US04749703,1,Fc1ccc(N2CCNCC2)cc1.O=C(CCCCl)NC1c2ccccc2CSc2ccccc21>>O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2ccccc2CSc2ccccc21 -US20150025068A1,1,O=C(O)c1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)cc1O.Oc1ccccc1>>O=C(Oc1ccccc1)c1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)cc1O -US05028606,7,O=C(c1ccccc1)c1ccc2nccnc2c1>>OC(c1ccccc1)c1ccc2nccnc2c1 -US04690931,1,COc1ccc(C(=O)C(C)Br)cc1OC.Cc1ccc(CC2CCNCC2)cc1>>COc1ccc(C(=O)C(C)N2CCC(Cc3ccc(C)cc3)CC2)cc1OC -US20110105470A1,2,O=C(Cl)c1cccc(Cl)c1.O=C1C(=O)c2ccc(-c3ccncc3)cc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccc(-c3ccncc3)cc2C2=C1SCC1(CCN(C(=O)c3cccc(Cl)c3)CC1)O2 -US09018382B2,2,CCCc1cc(C)[nH]c(=O)c1CN.O=C(O)c1cc(Br)cc2c1cnn2C1CC1>>CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Br)cc2c1cnn2C1CC1 -US04556667,1,O=C1c2ccccc2C(=O)N1CCCBr.c1ccc(C2=Nc3cccnc3Nc3ccccc32)cc1>>O=C1c2ccccc2C(=O)N1CCCN1c2ccccc2C(c2ccccc2)=Nc2cccnc21 -US20150148333A1,3,Cc1noc2c1-c1ccc(Cl)cc1N(c1ccc(C#N)cc1)C(=O)C2.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cc1noc2c1-c1ccc(-c3cnn(C)c3)cc1N(c1ccc(C#N)cc1)C(=O)C2 -US05919936,2,Nc1ccc2[nH]cc(C3CCN(CCc4ccccc4)CC3)c2n1.O=C(Cl)c1ccccc1>>O=C(Nc1ccc2[nH]cc(C3CCN(CCc4ccccc4)CC3)c2n1)c1ccccc1 -US06951879B2,1,BrCCCCBr.Oc1ccc2c(-c3ccc(Cl)cc3)nsc2c1>>Clc1ccc(-c2nsc3cc(OCCCCBr)ccc23)cc1 -US20120329818A1,1,CN(C)C(=O)Oc1cccc(NC(=O)C2(OCc3ccccc3)CCNCC2)c1.Cc1c[nH]c2ncnc(Cl)c12>>Cc1c[nH]c2ncnc(N3CCC(OCc4ccccc4)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12 -US20070208015A1,6,CCOC(=O)c1cc(F)cc(N2CCOCC2)c1>>O=C(O)c1cc(F)cc(N2CCOCC2)c1 -US20130045169A1,6,CC(C)(C)OC(=O)NC(c1ccccc1)c1cccc(OCc2ccc(C(=O)OCCCC3OCCO3)cc2)c1>>NC(c1ccccc1)c1cccc(OCc2ccc(C(=O)OCCCC3OCCO3)cc2)c1 -US08975254B2,2,C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.Cc1nnc(C(=O)O)o1>>Cc1nnc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)o1 -US08754075B2,2,C[C@]1(c2cc(N)ccc2F)N=C(N)OC[C@@H]1F.O=C(O)c1cnc(C(F)F)cn1>>C[C@]1(c2cc(NC(=O)c3cnc(C(F)F)cn3)ccc2F)N=C(N)OC[C@@H]1F -US07223773B2,7,CCOC(=O)c1cc(C2CC2)c2c(C)c(-c3ccc(C(C)=O)cc3)ccn2c1=O>>CCOC(=O)c1cc(C2CC2)c2c(C)c(-c3ccc(C(C)O)cc3)ccn2c1=O -US08580962B2,3,CCOC(=O)N1CCC2(CC1)CC(=O)CO2.[Mg+]C#Cc1ccccc1>>CCOC(=O)N1CCC2(CC1)CC(O)(C#Cc1ccccc1)CO2 -US04089976,6,CO[C@@H]1CC[C@@H](NC(C)=O)c2ccccc21>>CO[C@@H]1CC[C@@H](N)c2ccccc21 -US05436254,1,NC1CCN(Cc2ccccc2)CC1.O=C(O)c1c(F)cccc1Cl>>O=C(O)c1c(F)cccc1NC1CCN(Cc2ccccc2)CC1 -US20070049581A1,6,CC(C)(C)OC(=O)N1CCN(C2(C)CCN(Cc3ccccc3)CC2)CC1>>CC(C)(C)OC(=O)N1CCN(C2(C)CCNCC2)CC1 -US05246965,1,ClCCCCCBr.N#Cc1ccc(O)cc1>>N#Cc1ccc(OCCCCCCl)cc1 -US20130109661A1,1,CC1CNCC(C)C1.Nc1cccc(F)n1>>CC1CC(C)CN(c2cccc(N)n2)C1 -US20040087568A1,2,CC(C)(C)OC(=O)N1Cc2cc(N)ccc2C(C)(C)C1.Nc1ccccc1C(=O)O>>CC(C)(C)OC(=O)N1Cc2cc(NC(=O)c3ccccc3N)ccc2C(C)(C)C1 -US20060257987A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1ccc(OCc2ccccc2)cc1C(F)(F)F>>CCOC(=O)C=Cc1ccc(OCc2ccccc2)cc1C(F)(F)F -US06583135B2,2,CC(C)(C)OC(=O)N1CCc2c(n(CC(=O)O)c3cc(Cl)c(Cl)cc23)CC1.COc1ccc(N)cc1>>COc1ccc(NC(=O)Cn2c3c(c4cc(Cl)c(Cl)cc42)CCN(C(=O)OC(C)(C)C)CC3)cc1 -US20030087874A1,6,COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@H](Cc4ccccc4)NC(=O)OCc4ccccc4)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1>>COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@@H](N)Cc4ccccc4)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1 -US20060235007A1,3,C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1.Cc1ccccc1B(O)O>>Cc1ccccc1-c1ccc2c(c1)C(=O)N([C@H](C)c1ccc(Cl)cc1)[C@@H](c1ccc(Cl)cc1)C(=O)N2 -US06482951B2,2,Nc1ncc(Cl)s1.O=C(O)[C@H](CC1CCCCC1)N1Cc2c(Cl)cccc2C1=O>>O=C(Nc1ncc(Cl)s1)[C@H](CC1CCCCC1)N1Cc2c(Cl)cccc2C1=O -US20090099187A1,1,COc1ccc(S(N)(=O)=O)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2.Clc1ncccn1>>COc1ccc(S(=O)(=O)Nc2ncccn2)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2 -US20110092461A1,2,CC(C)(C)N.O=C(O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cc1>>CC(C)(C)NC(=O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cc1 -US20110251166A1,3,CCOC(=O)C(F)(F)Br.O=Cc1ccccc1>>CCOC(=O)C(F)(F)C(O)c1ccccc1 -US08940724B2,1,Cc1c(-c2ccnc(N3CCCC3)c2)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>Cc1c(-c2ccnc(N3CCCC3)c2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1 -US06855512B2,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCC3=O)cc1F>>CC1(C)CCC(=O)c2ccc(C#Cc3ccc(C(=O)O)c(F)c3)cc21 -US20120208852A1,6,CC(C)(C)OC(=O)NC(c1cccc(C(F)(F)F)c1)c1ncco1>>NC(c1cccc(C(F)(F)F)c1)c1ncco1 -US20080176862A1,3,CN1C(=O)C(c2ccc(O)cc2)(c2ccc(F)c(Br)c2)N=C1N.COc1cncc(Br)c1>>COc1cncc(-c2cc(C3(c4ccc(O)cc4)N=C(N)N(C)C3=O)ccc2F)c1 -US20100239576A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCc1ccccc1>>COc1cc2c(Oc3ccc(NC(=O)OC(C)(C)C)cc3F)ccnc2cc1OCc1ccccc1 -US08344135B2,6,COc1cc([N+](=O)[O-])ccc1C(F)(F)F>>O=[N+]([O-])c1ccc(C(F)(F)F)c(O)c1 -US20040058965A1,6,CCCc1ccc(OCc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(CC(=O)OC)c1>>CCCc1ccc(OCc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(CC(=O)O)c1 -US20100324140A1,6,COC(=O)c1ccc(C(CC(C)C)Oc2ccc(Br)c(C3OCCCO3)c2)cc1>>CC(C)CC(Oc1ccc(Br)c(C2OCCCO2)c1)c1ccc(C(=O)O)cc1 -US20120108574A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccc5cnccc5c4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1>>NC1(c2ccc(-c3c(-c4ccc5cnccc5c4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1 -US20090270434A1,1,Clc1ncc(Br)cn1.Fc1ccc(Br)c(OC2CCNCC2)c1>>Fc1ccc(Br)c(OC2CCN(c3ncc(Br)cn3)CC2)c1 -US08637532B2,6,CC(C)(C)OC(=O)NC(CCO)c1cccc(NC(=O)c2cc(C3CC3)n[nH]2)c1>>NC(CCO)c1cccc(NC(=O)c2cc(C3CC3)n[nH]2)c1 -US07705030B2,3,C[Si](C)(C)C#Cc1cccc(Br)c1.OB(O)c1cccnc1F>>C[Si](C)(C)C#Cc1cccc(-c2cccnc2F)c1 -US20140051679A1,6,O=C(Nc1ccc2c(c1)c(I)nn2C1CCCCO1)C(c1ccccc1)C1CC1>>O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccccc1)C1CC1 -US20050026987A1,3,COC(=O)CN=[N+]=[N-].O=Cc1cccc(OC(F)(F)F)c1>>COC(=O)C(=Cc1cccc(OC(F)(F)F)c1)N=[N+]=[N-] -US20090318690A1,1,C1=COCCC1.CC(=O)c1cc(O)ccc1O>>CC(=O)c1cc(OC2CCCCO2)ccc1O -US07820660B2,2,CC(C)(C)C(=O)Cl.COC(=O)c1ncnc(O)c1O>>COC(=O)c1ncnc(O)c1OC(=O)C(C)(C)C -US20110092491A1,1,CC(=O)c1ccc(Nc2nc(F)nc3c2ncn3C2CCCCO2)cc1.CNC1CCN(C)CC1>>CC(=O)c1ccc(Nc2nc(N(C)C3CCN(C)CC3)nc3c2ncn3C2CCCCO2)cc1 -US20070093548A1,6,CCC(C)c1c(OC)cccc1OC>>CCC(C)c1c(O)cccc1OC -US20070037829A1,6,CC(C)(C)OC(=O)N[C@H]1CC[C@H](NC(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)N[C@H]1CC[C@H](N)C1 -US20060247238A1,8,CC(C)(C)OC(=O)N1C[C@@H](O)[C@H](CNC(=O)c2ccc(Cl)s2)C1>>CC(C)(C)OC(=O)N1CC(=O)[C@H](CNC(=O)c2ccc(Cl)s2)C1 -US07384965B2,1,CCOC(=O)COc1ccc(S)cc1C.FC(F)(F)c1ccc(-c2nc3cccc(CBr)c3s2)cc1>>CCOC(=O)COc1ccc(SCc2cccc3nc(-c4ccc(C(F)(F)F)cc4)sc23)cc1C -US20130158075A1,2,CC(C)(CCc1ncc(-c2ccc([N+](=O)[O-])cc2)s1)C(=O)O.NS(=O)(=O)C(F)(F)F>>CC(C)(CCc1ncc(-c2ccc([N+](=O)[O-])cc2)s1)C(=O)NS(=O)(=O)C(F)(F)F -US20020114770A1,1,CC(C)(C)[Si](C)(C)Oc1ccc(C2CCC(=O)CC2)c(O[Si](C)(C)C(C)(C)C)c1.NCc1ccccc1>>CC(C)(C)[Si](C)(C)Oc1ccc(C2CCC(=NCc3ccccc3)CC2)c(O[Si](C)(C)C(C)(C)C)c1 -US05925647,2,CO.O=C(O)c1c2nc3ccccc3c-2[nH]c2ccccc12>>COC(=O)c1c2nc3ccccc3c-2[nH]c2ccccc12 -US07030116B2,2,CC(C)CC(C)(C)C[C@H](CC(=O)N1CCOCC1)C(=O)O.CC[C@H](N)C(=O)c1ncco1>>CC[C@H](NC(=O)[C@@H](CC(=O)N1CCOCC1)CC(C)(C)CC(C)C)C(=O)c1ncco1 -US20070123507A1,8,OC1CN(C(c2ccccc2)c2ccccc2)C1>>O=C1CN(C(c2ccccc2)c2ccccc2)C1 -US04808750,1,COC(=O)C(C)O.Oc1ccc(Oc2ccc(Cl)cc2F)cc1>>COC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2F)cc1 -US20090298836A1,7,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)nc1)C(=O)C1C(=O)OC(C)(C)OC1=O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)nc1)CC1C(=O)OC(C)(C)OC1=O -US20070078175A1,7,O=C1NC(=O)C(=Cc2ccc(-c3cccc(C(F)(F)F)c3)o2)S1>>O=C1NC(=O)C(Cc2ccc(-c3cccc(C(F)(F)F)c3)o2)S1 -US20110178140A1,8,CSc1c(-c2nnc(C(C)(C)C)s2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1c(-c2nnc(C(C)(C)C)s2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 -US20070043011A1,1,CI.Cc1cc(C(O)(c2ccc(Cl)cc2)C(F)(F)F)ccc1N>>COC(c1ccc(Cl)cc1)(c1ccc(N)c(C)c1)C(F)(F)F -US04808595,1,CN(C)CCN.NS(=O)(=O)c1cc2c(Cl)nccc2o1>>CN(C)CCNc1nccc2oc(S(N)(=O)=O)cc12 -US20120190701A1,7,COC(=O)c1cc(Br)cc2ccccc12>>OCc1cc(Br)cc2ccccc12 -US09115159B2,6,Cn1ccc2cc(N(C(=O)c3cc(-c4ccc(OCc5ccccc5)cc4C(=O)N4Cc5ccccc5C[C@H]4CN4CCOCC4)n4c3CCCC4)c3ccc(O[Si](C)(C)C(C)(C)C)cc3)cnc21>>Cn1ccc2cc(N(C(=O)c3cc(-c4ccc(O)cc4C(=O)N4Cc5ccccc5C[C@H]4CN4CCOCC4)n4c3CCCC4)c3ccc(O[Si](C)(C)C(C)(C)C)cc3)cnc21 -US20130217736A1,9,NO.O=Cc1ccc(Br)c2ccccc12>>ON=Cc1ccc(Br)c2ccccc12 -US06482849B1,7,COC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(O)c(N)c1)NC(=O)OC(C)(C)C -US09072731B2,3,CCOC(=O)c1sc(-c2ccc(Cl)cc2)cc1Br.NS(=O)(=O)c1ccc(B(O)O)cc1>>CCOC(=O)c1sc(-c2ccc(Cl)cc2)cc1-c1ccc(S(N)(=O)=O)cc1 -US20030166689A1,2,Nc1nc(-c2ccccc2)cs1.O=S(=O)(Cl)c1c(Cl)cc(Cl)cc1Cl>>O=S(=O)(Nc1nc(-c2ccccc2)cs1)c1c(Cl)cc(Cl)cc1Cl -US20140275152A1,7,CCOC(=O)C1=C(c2ccnn2C(C)C)COCC1>>CC(C)n1nccc1C1=C(CO)CCOC1 -US06214992B1,1,ClCOc1ccc(Cl)cc1.Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1>>Cn1c(=O)n(COc2ccc(Cl)cc2)c(=O)c2c1ncn2Cc1ccccc1 -US07601743B2,9,Cc1cc(I)cc2c(=O)oc(=O)[nH]c12.N#C[Cu]>>Cc1cc(C#N)cc2c(=O)oc(=O)[nH]c12 -US07759385B2,2,CN(C)C1(c2ccccc2)CCC(=CC(=O)O)CC1.c1ccc2c(C3CCNC3)c[nH]c2c1>>CN(C)C1(c2ccccc2)CCC(=CC(=O)N2CCC(c3c[nH]c4ccccc34)C2)CC1 -US20080255105A1,2,CCOC(=O)c1ccc(-c2cc(N)ccc2C)cc1.O=C(Cl)c1cccs1>>CCOC(=O)c1ccc(-c2cc(NC(=O)c3cccs3)ccc2C)cc1 -US20120252780A1,1,CCOC(=O)CBr.Cc1cc(Br)nc([N+](=O)[O-])c1O>>CCOC(=O)COc1c(C)cc(Br)nc1[N+](=O)[O-] -US20080176830A1,3,O=C1CSc2cc(Br)ccc2N1.O=S(=O)(c1ccc(Cl)cc1)C(F)(F)F>>O=C1CSc2cc(-c3ccc(S(=O)(=O)C(F)(F)F)cc3)ccc2N1 -US20090099229A1,2,CC(=O)Cl.COc1cc(C(O)C(=O)O)cc(OC)c1OC>>COc1cc(C(OC(C)=O)C(=O)O)cc(OC)c1OC -US20050250818A1,2,COC(=O)c1ccc([C@H](C)N)cc1.O=C(O)c1cc(Cl)cnc1OCc1ccc(Cl)cc1>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)cnc2OCc2ccc(Cl)cc2)cc1 -US20060004084A1,3,O=C1Cc2cc(F)ccc2N1.O=C1OCc2cc(CCCN3CCS(=O)(=O)CC3)ccc21>>O=C1Nc2ccc(F)cc2C1=C1OCc2cc(CCCN3CCS(=O)(=O)CC3)ccc21 -US05725798,1,BrCc1ccccc1.O=C(O)C1CCc2cc(O)ccc2C1>>O=C(O)C1CCc2cc(OCc3ccccc3)ccc2C1 -US20090176804A1,2,NCc1ccc(Cl)cc1Cl.O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)Cl)c1>>O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)NCc2ccc(Cl)cc2Cl)c1 -US04971967,1,Fc1ccc(NC(=S)[S-])c(F)c1F.O=C(CCl)CCl>>O=C(CCl)CSC(=S)Nc1ccc(F)c(F)c1F -US20140357637A1,9,CCOC(=O)c1nn(Cc2ccccc2F)c(Cl)c1C=O.[N-]=[N+]=[N-]>>CCOC(=O)c1nn(Cc2ccccc2F)c(N=[N+]=[N-])c1C=O -US20030069233A1,7,COc1ccc(N)cc1N1CCN(C(=O)C2CC2)CC1>>COc1ccc(N)cc1N1CCN(CC2CC2)CC1 -US06350761B1,1,BrCc1ccccc1.N#Cc1ccc(O)c([N+](=O)[O-])c1>>N#Cc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1 -US20140128429A1,3,CON(C)C(=O)c1cncn1C.COc1ccc(Br)cc1>>COc1ccc(C(=O)c2cncn2C)cc1 -US04564609,6,O=C1C[C@@H](C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N2CCC[C@H]2C(=O)OCc2ccccc2)N1>>O=C1C[C@@H](C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N2CCC[C@H]2C(=O)O)N1 -US05424308,1,CCI.N#CC(C(=O)Nc1ccccc1)C(=O)c1nn(-c2ccccc2)c2c1Cc1c(C(=O)O)cccc1-2>>CCOC(=O)c1cccc2c1Cc1c(C(=O)C(C#N)C(=O)Nc3ccccc3)nn(-c3ccccc3)c1-2 -US20070185079A1,2,CS(=O)(=O)Cl.Cc1cc(Cl)nc2cc(O)ccc12>>Cc1cc(Cl)nc2cc(OS(C)(=O)=O)ccc12 -US20040236084A1,1,CSc1ncc(C=O)c(NC2CCCC2)n1.NCc1ccccc1>>CSc1ncc(C=NCc2ccccc2)c(NC2CCCC2)n1 -US20100249123A1,2,CC(C)(C#N)c1ccc(N)cc1.COc1ccc(C(=O)O)c(Cl)c1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)cc2)c(Cl)c1OC -US08901087B2,7,CN(C)C1=N[C@H]2[C@H](O[C@H](COC(=O)c3ccccc3)[C@H]3OC(C)(C)O[C@H]23)S1>>CN(C)C1=N[C@H]2[C@H](O[C@H](CO)[C@H]3OC(C)(C)O[C@H]23)S1 -US05270302,6,CCOC(=O)C(C)(Cc1c[nH]c2ccccc12)C(=O)OCC>>CCOC(=O)C(C)(Cc1c[nH]c2ccccc12)C(=O)O -US20050010031A1,2,COCC(N)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)OC.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>COCC(NS(=O)(=O)c1ccccc1[N+](=O)[O-])C(=O)NC(Cc1ccc2ccccc2c1)C(=O)OC -US07759369B2,3,CCOC(=O)c1cccc(CCl)n1.OB(O)c1cc(Cl)ccc1OCc1ccc(Cl)cc1F>>CCOC(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 -US08618162B2,1,CC(C)CI.Oc1ccccc1O>>CC(C)COc1ccccc1O -US20060281799A1,7,O=C1CCc2cccc(Nc3ncc(-c4ccc(N5CCCC5)cc4)o3)c2C1>>OC1CCc2cccc(Nc3ncc(-c4ccc(N5CCCC5)cc4)o3)c2C1 -US20060025400A1,2,CN[C@@H]1CCCc2cc(CN3CCCCC3)ccc21.Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)O)cc1>>Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)N(C)[C@@H]2CCCc3cc(CN4CCCCC4)ccc32)cc1 -US20130252890A1,1,CNCCCCCS(=O)(=O)CCC(F)(F)F.Oc1ccc2c(c1)CCCC(c1cc(F)cc(F)c1)=C2CCCCCCBr>>CN(CCCCCCC1=C(c2cc(F)cc(F)c2)CCCc2cc(O)ccc21)CCCCCS(=O)(=O)CCC(F)(F)F -US07632857B2,3,O=C(c1ccc(Br)cc1)N1CCC[C@H]1CN1CCCC1.OB(O)c1ccc2c(c1)OCO2>>O=C(c1ccc(-c2ccc3c(c2)OCO3)cc1)N1CCC[C@H]1CN1CCCC1 -US06403804B1,7,COCC(=O)CC(=O)OC>>COC[C@H](O)CC(=O)OC -US05457106,5,CCCCCCCCCCCCNCCCSc1ccncc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCCCCCCCCCCCN(CCCSc1ccncc1)C(=O)C(F)(F)F -US07125990B2,7,Cc1cc(C)c(Nc2ccc(F)cc2[N+](=O)[O-])c(C)c1>>Cc1cc(C)c(Nc2ccc(F)cc2N)c(C)c1 -US07763624B2,1,C=CCCN(N)c1nc(Cl)ncc1C(=O)Nc1c(C)cccc1C>>C=CCCn1nc(Nc2c(C)cccc2C)c2cnc(Cl)nc21 -US20090197875A1,1,C1COCCN1.COc1cc(F)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1>>COc1cc(N2CCOCC2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1 -US20090186876A1,2,CCOC(=O)c1cnc(N2CCNCC2)c(Cl)c1.O=C=NCc1ccccc1>>CCOC(=O)c1cnc(N2CCN(C(=O)NCc3ccccc3)CC2)c(Cl)c1 -US07776897B2,5,CCOC(=O)C(C)(C)C(O)c1ccccc1.COCCl>>CCOC(=O)C(C)(C)C(OCOC)c1ccccc1 -US20100041892A1,6,CCOC(=O)CCc1cc(OCCOC)nn1Cc1ccc(Cl)cc1Cl>>COCCOc1cc(CCC(=O)O)n(Cc2ccc(Cl)cc2Cl)n1 -US20150045393A1,6,CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)Nc1c(C)cc(C)cc1C>>Cc1cc(C)c(NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]2O[C@@H]2C(=O)O)c(C)c1 -US20150218165A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CNc1ccc(F)cc1Br>>CNc1ccc(F)cc1B1OC(C)(C)C(C)(C)O1 -US05166367,1,NCC1COc2ccccc2O1.O=c1ccc2ccc(OCCCCl)cc2o1>>O=c1ccc2ccc(OCCCNCC3COc4ccccc4O3)cc2o1 -US20070249637A1,2,COC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](N)C(=O)N1C[C@H](Oc3nc(-c4cc(C)nn4C)nc4ccsc34)C[C@H]1C(=O)N2.O=C(O)CC1CC1>>COC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)CC1CC1)C(=O)N1C[C@H](Oc3nc(-c4cc(C)nn4C)nc4ccsc34)C[C@H]1C(=O)N2 -US07910595B2,7,COC(=O)c1ccc(Oc2ccc(NC(=O)OC(C)(C)C)cc2)c([N+](=O)[O-])c1>>COC(=O)c1ccc(Oc2ccc(NC(=O)OC(C)(C)C)cc2)c(N)c1 -US20100041892A1,6,COC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ncc(C(F)(F)F)cc1Cl>>CC(C)Oc1cc(/C=C/C(=O)O)n(Cc2ncc(C(F)(F)F)cc2Cl)n1 -US20040132798A1,2,COC(=O)CN.O=C(Cl)c1ccc2ccccc2c1>>COC(=O)CNC(=O)c1ccc2ccccc2c1 -US20020035137A1,6,CCCCCNC(=O)C(Cc1ccc([N+](=O)[O-])cc1)NC(=O)OC(C)(C)C>>CCCCCNC(=O)C(N)Cc1ccc([N+](=O)[O-])cc1 -US20140356322A1,6,Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)OCc2ccccc2)on1>>Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)O)on1 -US20050014767A1,3,CC(C)(C)[Si](C)(C)Oc1ccc(B(O)O)cc1OCc1ccccc1.O=Cc1ccc(Br)nc1>>CC(C)(C)[Si](C)(C)Oc1ccc(-c2ccc(C=O)cn2)cc1OCc1ccccc1 -US20060199829A1,7,COC(=O)c1cnc(N2CCc3[nH]c4ccc([N+](=O)[O-])cc4c3C2)nc1>>COC(=O)c1cnc(N2CCc3[nH]c4ccc(N)cc4c3C2)nc1 -US04268514,6,C#CCN1CCC2(CC1)c1ccccc1Oc1c(OC(C)=O)cccc12>>C#CCN1CCC2(CC1)c1ccccc1Oc1c(O)cccc12 -US20040063691A1,10,CCOC(=O)C(=O)CC1CC1.O=C1CCC(=O)N1Br>>CCOC(=O)C(=O)C(Br)C1CC1 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CCCCCC(O)c3ccccc3)CC2)c1.Oc1ccc(F)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCCC(Oc3ccc(F)cc3)c3ccccc3)CC2)c1 -US05716936,6,CC(C)CNC(=O)C1CC(S(=O)(=O)c2ccccc2F)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1>>CC(C)CNC(=O)C1CC(S(=O)(=O)c2ccccc2F)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)O)c1 -US04032567,2,COC(=O)c1cc(C(=O)Cl)cc([N+](=O)[O-])c1.NCC(=O)O>>COC(=O)c1cc(C(=O)NCC(=O)O)cc([N+](=O)[O-])c1 -US20090054405A1,3,CC(=O)Nc1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2s1.N#CCOc1cncc(Br)c1>>CC(=O)Nc1nc2ccc(-c3cncc(OCC#N)c3)cc2s1 -US20120149694A1,8,CCSCC1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)CC1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1 -US04355174,6,COC(=O)c1cc(-c2ccc(F)cc2F)ccc1O>>O=C(O)c1cc(-c2ccc(F)cc2F)ccc1O -US08178520B2,6,COC(=O)[C@@H]1C[C@H](OS(=O)(=O)c2ccc(Br)cc2)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@H](OS(=O)(=O)c2ccc(Br)cc2)CN1 -US06093345,7,CCOC(=O)[C@@H](OC1CCCCO1)[C@@H](C)CC>>CC[C@H](C)[C@@H](CO)OC1CCCCO1 -US20070225319A1,7,CCOC(=O)Cc1coc2c1ccc1ccccc12>>OCCc1coc2c1ccc1ccccc12 -US07429585B2,6,CC(C)(C)OC(=O)N1CCN(c2ccc3cc(Cl)ccc3n2)CC1>>Clc1ccc2nc(N3CCNCC3)ccc2c1 -US20070010542A1,7,CC1(C)OCC(=O)CO1>>CC1(C)OCC(O)CO1 -US04460584,1,Cc1ncc[nH]1.OCCCCl>>Cc1nccn1CCCO -US20060069132A1,2,CCN.CCn1nc(C(C)(C)C)cc1C(=O)Nc1cc(C(=O)O)ccc1F>>CCNC(=O)c1ccc(F)c(NC(=O)c2cc(C(C)(C)C)nn2CC)c1 -US20090023725A1,3,Cc1ccc(C(=O)NC2CCC2)cc1B1OC(C)(C)C(C)(C)O1.Fc1ccc(-n2ncc3cc(Br)ccc32)cc1>>Cc1ccc(C(=O)NC2CCC2)cc1-c1ccc2c(cnn2-c2ccc(F)cc2)c1 -US04388104,7,CC1=COC(C)(C=O)CC1>>CC1=COC(C)(CO)CC1 -US20100317643A1,9,[N-]=[N+]=Nc1cc(NC(=O)c2c(Cl)cc(Cl)cc2Cl)ccn1>>Nc1cc(NC(=O)c2c(Cl)cc(Cl)cc2Cl)ccn1 -US20050153955A1,6,CCOC(=O)CCNC(=O)c1cc(Br)c(Br)[nH]1>>O=C(O)CCNC(=O)c1cc(Br)c(Br)[nH]1 -US06297375B1,3,CN1CCN(c2cc(I)c(NC(=O)C(C)(C)C)cn2)CC1.Cc1ccccc1B(O)O>>Cc1ccccc1-c1cc(N2CCN(C)CC2)ncc1NC(=O)C(C)(C)C -US20150038416A1,6,CCCCCCCOc1ccc(-c2noc(-c3ccc(C[C@H](NC(=O)c4ccc(C(C)(C)C)cc4)C(=O)OC)cc3)n2)cc1>>CCCCCCCOc1ccc(-c2noc(-c3ccc(C[C@H](NC(=O)c4ccc(C(C)(C)C)cc4)C(=O)O)cc3)n2)cc1 -US08501950B2,2,Cc1cc(Cl)cc(C(=O)NC(C)(C#N)C2CC2)c1N.O=C(Cl)c1cc(C(F)(F)F)nn1-c1ncccc1Cl>>Cc1cc(Cl)cc(C(=O)NC(C)(C#N)C2CC2)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl -US06660735B2,1,CC(C)(C)OC(=O)NCCOCCN=[N+]=[N-].CI>>CN(CCOCCN=[N+]=[N-])C(=O)OC(C)(C)C -US09079866B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(CN)S(=O)(=O)c1ccccc1Br>>CC(C)(C)OC(=O)NCC(C)(C)S(=O)(=O)c1ccccc1Br -US08268822B2,1,CC(C)(C)OC(=O)N1CCNCC1c1ccccc1.O=Cc1cccc(-c2ccnc(Cl)n2)c1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(-c3ccnc(Cl)n3)c2)C[C@H]1c1ccccc1 -US20140356322A1,2,CCOc1cccc(C(=O)O)c1.O=C(O)[C@@H]1C[C@@H](O)CN1>>CCOc1cccc(C(=O)N2C[C@H](O)C[C@H]2C(=O)O)c1 -US20070004765A1,4,C[Si](C)(C)N=[N+]=[N-].N#Cc1ccc2[nH]c3c(c2c1)CCNC31CCN(CCOc2ccccc2)C1>>c1ccc(OCCN2CCC3(C2)NCCc2c3[nH]c3ccc(-c4nnn[nH]4)cc23)cc1 -US08530648B2,1,Cc1ccc(C)c(CCl)c1.O=C1CCCC2(CCN(c3cnc4ccccc4n3)CC2)N1>>Cc1ccc(C)c(CN2C(=O)CCCC23CCN(c2cnc4ccccc4n2)CC3)c1 -US05434154,1,CNS(=O)(=O)Cc1ccc2[nH]cc(CCCOS(C)(=O)=O)c2c1.COc1cncnc1N1CCNCC1>>CNS(=O)(=O)Cc1ccc2[nH]cc(CCCN3CCN(c4ncncc4OC)CC3)c2c1 -US20090233928A1,6,CCOC(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C(C)C)n2)nc1>>Cc1ncc(-c2ccnc(Nc3ccc(C(=O)O)cn3)n2)n1C(C)C -US06472386B1,1,COc1cc(B(O)O)cc(OC)c1OC.C[SiH](C)OC(c1c[nH]cn1)C(C)(C)C>>COc1cc(-n2cnc(C(O[SiH](C)C)C(C)(C)C)c2)cc(OC)c1OC -US20130296312A1,1,CS(=O)(=O)c1cccc(N)c1.Clc1nc2c(Br)cccn2n1>>CS(=O)(=O)c1cccc(Nc2cccn3nc(Cl)nc23)c1 -US20040138223A1,2,CC(C)c1ccc(NCc2ccc(N(C)C)cc2)cc1.O=C(O)C1CCOc2ccc(Br)cc21>>CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCOc3ccc(Br)cc32)cc1 -US08877780B2,2,NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O.O=C=Nc1cc(C(F)(F)F)ccc1Cl>>O=C1CCC(N2Cc3cc(CNC(=O)Nc4cc(C(F)(F)F)ccc4Cl)ccc3C2=O)C(=O)N1 -US20060205790A1,1,BrCc1ccccc1.CC(=O)c1ccc(O)cc1C>>CC(=O)c1ccc(OCc2ccccc2)cc1C -US08623866B2,7,CNC(=O)c1nn(C)cc1[N+](=O)[O-]>>CNC(=O)c1nn(C)cc1N -US06693123B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(C(=O)O)c2ccccc12>>CC(C)(C)OC(=O)Nc1ccc(C(=O)O)c2ccccc12 -US20130040930A1,1,Cc1ccc(N2CCN(C(=O)c3ccc(Br)cc3)CC2)c(C)c1.O=C1NC2C=CC1C2>>Cc1ccc(N2CCN(C(=O)c3ccc(N4C(=O)C5C=CC4C5)cc3)CC2)c(C)c1 -US05998444,2,NCC(c1ccc(Cl)c(Cl)c1)N1CCCC1.O=C(Cl)c1ccccc1>>O=C(NCC(c1ccc(Cl)c(Cl)c1)N1CCCC1)c1ccccc1 -US05977149,1,C[O-].Cc1ccccc1-n1c(Cl)nn(C)c1=O>>COc1nn(C)c(=O)n1-c1ccccc1C -US05411980,2,CCC(=O)Br.CCCCc1nn(-c2cc(N)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Oc2ccccc2)cc1>>CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Oc2ccccc2)cc1 -US08222424B2,3,C[Sn](C)(C)c1ccc2c3c([nH]c2c1)C(=O)NCC3.NS(=O)(=O)c1cc(C(=O)Cl)ccc1Cl>>NS(=O)(=O)c1cc(C(=O)c2ccc3c4c([nH]c3c2)C(=O)NCC4)ccc1Cl -US20130317023A1,6,O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F)c1ccsc1>>O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)c1ccsc1 -US08404866B2,8,CC(C)(C)OC(=O)N1CC=CC1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)[N+]1([O-])CC=CC1 -US20150239838A1,6,CC(=O)c1ccc(Cl)c(-c2cccc(NC(=O)[C@@H]3C[C@@H](F)CN3C(=O)OC(C)(C)C)c2F)c1>>CC(=O)c1ccc(Cl)c(-c2cccc(NC(=O)[C@@H]3C[C@@H](F)CN3)c2F)c1 -US06013649,1,Fc1ccc(S)cc1.OCCCCl>>OCCCSc1ccc(F)cc1 -US20120071516A1,3,Cc1nc2cc(Cl)c(B3OC(C)(C)C(C)(C)O3)cc2o1.O=C(Nc1ccccc1F)c1ccc(Br)[se]1>>Cc1nc2cc(Cl)c(-c3ccc(C(=O)Nc4ccccc4F)[se]3)cc2o1 -US04820844,6,COCC(O)Cn1nc([N+](=O)[O-])nc1C(=O)OC>>COCC(O)Cn1nc([N+](=O)[O-])nc1C(=O)O -US20150031674A1,9,Clc1cc(Br)ccc1CBr.[C-]#N>>N#CCc1ccc(Br)cc1Cl -US20100286152A1,2,NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C(c1ccccc1Cl)N1CCN2CCC[C@@H]2C1>>O=C(NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(c1ccccc1Cl)N1CCN2CCC[C@@H]2C1 -US20150225412A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=[N+]([O-])c1ccccc1F>>CC(C)(C)OC(=O)N1CCC(Nc2ccccc2[N+](=O)[O-])CC1 -US20080269335A1,6,CCOC(=O)COc1ccc(-c2ccc(F)c(F)c2)cc1C1CCCCC1>>O=C(O)COc1ccc(-c2ccc(F)c(F)c2)cc1C1CCCCC1 -US06900225B2,1,COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12.N[C@@H]1CNCC12CC2>>COc1c(N2C[C@@H](N)C3(CC3)C2)c(F)cc2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12 -US20140171435A1,1,CCCN.Nc1c(Cl)cnnc1Cl>>CCCNc1nncc(Cl)c1N -US20090048258A1,2,CCOc1ccc(C(=O)NCCN)cc1.O=C(O)c1cn(-c2ccccc2)nc1C(F)(F)F>>CCOc1ccc(C(=O)NCCNC(=O)c2cn(-c3ccccc3)nc2C(F)(F)F)cc1 -US04596870,1,Cc1ccc(OCCl)cc1.O=c1ncc(Cl)c[nH]1>>Cc1ccc(OCn2cc(Cl)cnc2=O)cc1 -US08697737B2,2,CO.Nc1ccc(C(=O)c2ccccc2C(=O)O)cc1[N+](=O)[O-]>>COC(=O)c1ccccc1C(=O)c1ccc(N)c([N+](=O)[O-])c1 -US20140155394A1,1,CCOc1cc(Nc2nc(Cl)ccc2[N+](=O)[O-])n[nH]1.C[C@H](N)c1ncc(F)cn1>>CCOc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)ccc2[N+](=O)[O-])n[nH]1 -US20140094462A1,4,O=C(C[C@@H]1CC=CCCC(=O)O[C@H](c2ccccc2)CNC1=O)NCc1ccc(Cl)cc1.O=C(OO)c1cccc(Cl)c1>>O=C(C[C@@H]1C[C@H]2O[C@@H]2CCC(=O)O[C@H](c2ccccc2)CNC1=O)NCc1ccc(Cl)cc1 -US20040147748A1,2,CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)O)cc1Cl.Nc1cnc(-c2ccco2)cn1>>CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2cnc(-c3ccco3)cn2)cc1Cl -US20090131444A1,6,COc1ccc2nccc(NC(=O)C3CCC(NC(=O)OC(C)(C)C)C(=O)N3)c2n1>>COc1ccc2nccc(NC(=O)C3CCC(N)C(=O)N3)c2n1 -US20110318266A1,7,O=C1c2ccccc2C(=O)N1c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2C(=O)c3ccccc3C2=O)cc1 -US09040522B2,2,C1CNCCN(C2CC2)C1.Cc1c(-c2cnn(-c3ccc(C(=O)O)cn3)c2O)ccc(C#N)c1F>>Cc1c(-c2cnn(-c3ccc(C(=O)N4CCCN(C5CC5)CC4)cn3)c2O)ccc(C#N)c1F -US20030139409A1,2,CC(=O)Cl.CN(C)CCNC(=O)c1cccc2nc3ccc4cc(N)ccc4c3nc12>>CC(=O)Nc1ccc2c(ccc3nc4cccc(C(=O)NCCN(C)C)c4nc32)c1 -US20070054916A1,3,Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1.Nc1ncc2cc(Br)ccc2n1>>Cc1ccc(C(=O)O)cc1-c1ccc2nc(N)ncc2c1 -US20070142305A1,2,CC(=O)Cl.COc1cc2c(c(N)c1OC)CCC2=O>>COc1cc2c(c(NC(C)=O)c1OC)CCC2=O -US20130274260A1,3,N#Cc1cccc(B(O)O)c1.O=C(NCc1c[nH]c2ccc(Cl)cc12)c1ccc(CCl)cc1>>N#Cc1cccc(Cc2ccc(C(=O)NCc3c[nH]c4ccc(Cl)cc34)cc2)c1 -US20110124635A1,1,CC(C)(O)C[C@]1(c2ccccc2)CCN([C@H]2CCNC2)C(=O)O1.COc1cnc(Cl)nc1>>COc1cnc(N2CC[C@H](N3CC[C@](CC(C)(C)O)(c4ccccc4)OC3=O)C2)nc1 -US20060229280A1,5,COC(=O)CC(C)(C)C=O.OCCO>>COC(=O)CC(C)(C)C1OCCO1 -US20130310427A1,6,COC(=O)[C@@H]1C=C(C)CN1C(=O)OC(C)(C)C>>CC1=C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1 -US20060287527A1,3,COC=O.O=C1Cc2ccccc2CO1>>CO/C=C1/C(=O)OCc2ccccc21 -US20140364433A1,1,Cc1ccc(-n2cccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)n1.FC(F)(F)c1ccc(Cl)nn1>>Cc1ccc(-n2cccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(C(F)(F)F)nn2)n1 -US20080269210A1,1,ClCCN1CCOCC1.Nc1ccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)cc1>>Clc1nc(N2CCOCC2)c2sc(-c3ccc(NCCN4CCOCC4)cc3)cc2n1 -US20060148801A1,3,COc1cc(C(=O)Cl)cc(OC)c1OC.Cc1ccc2cc[nH]c2n1>>COc1cc(C(=O)c2c[nH]c3nc(C)ccc23)cc(OC)c1OC -US04556677,9,CCC(C1CCCC1)C(O)(CC)c1ccc(OC)cc1>>CCC(c1ccc(OC)cc1)C(CC)C1CCCC1 -US20040167128A1,6,Cc1c(CO)ccc(NS(=O)(=O)c2ccc(F)cc2)c1C(=O)OCc1ccccc1>>Cc1c(CO)ccc(NS(=O)(=O)c2ccc(F)cc2)c1C(=O)O -US20110263571A1,2,Cc1cnc(N2CCNCC2)c(C2CC2)c1.O=C(O)c1ccc(Br)nc1>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)nc3)CC2)c(C2CC2)c1 -US08173650B2,1,CCc1nc2ccccc2[nH]1.C[C@H]1COCCN1c1nc(Cl)nc2c1nc(CN1CCC(C(C)(C)O)CC1)n2C>>CCc1nc2ccccc2n1-c1nc(N2CCOC[C@@H]2C)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1 -US04491465,2,C1CSCN1.O=C(Cl)Oc1ccc(Cl)c(OCC2CC2(Cl)Cl)c1>>O=C(Oc1ccc(Cl)c(OCC2CC2(Cl)Cl)c1)N1CCSC1 -US05338740,7,CCCCc1nc(C(=O)OCC)c(Cl)n1C1CCc2cc(Br)ccc21>>CCCCc1nc(CO)c(Cl)n1C1CCc2cc(Br)ccc21 -US04225606,7,CC(C)N1CCC(=Nc2ccccc2)CC1>>CC(C)N1CCC(Nc2ccccc2)CC1 -US05508433,2,CN(C)c1ccccc1CC(=O)O.Cl[C@H]1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12>>CN(C)c1ccccc1CC(=O)N1C[C@@H]2[C@@H](Cl)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1 -US20060281799A1,1,CC(C)(C)[Si](C)(C)OC1CCc2cccc(Nc3ncc(-c4ccc(C(F)(F)F)cc4)o3)c2C1.CI>>CN(c1ncc(-c2ccc(C(F)(F)F)cc2)o1)c1cccc2c1CC(O[Si](C)(C)C(C)(C)C)CC2 -US20110263607A1,2,CCOC(CN(Cc1cccc2ccccc12)C(=O)[C@@H](N)Cc1ccc(OC(C)(C)C)cc1)OCC.O=C(O)CONC(=O)NCc1ccccc1>>CCOC(CN(Cc1cccc2ccccc12)C(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)CONC(=O)NCc1ccccc1)OCC -US20080293712A1,1,CC(C)(C)OC(=O)N(CCO)Cc1ccc(F)cc1.COC(=O)c1cncc(O)c1>>COC(=O)c1cncc(OCCN(Cc2ccc(F)cc2)C(=O)OC(C)(C)C)c1 -US20150181868A1,1,BrCc1ccccc1.C=C[C@H](O)[C@@H](CCC(C)C)[C@H](C)OCc1ccc(OC)cc1>>C=C[C@H](OCc1ccccc1)[C@@H](CCC(C)C)[C@H](C)OCc1ccc(OC)cc1 -USRE039088E1,6,CCOC(=O)C1(CC)CCN(C(=O)OC(C)(C)C)CC1>>CCC1(C(=O)O)CCN(C(=O)OC(C)(C)C)CC1 -US08629166B2,2,Nc1cnccn1.O=C(O)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1>>O=C(Nc1cnccn1)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1 -US20140171417A1,1,CON(C)C(=O)CCCBr.Cn1ccc(-c2[nH]cc3c2c(=O)n(C)c(=O)n3C)n1>>CON(C)C(=O)CCCn1cc2c(c1-c1ccn(C)n1)c(=O)n(C)c(=O)n2C -US20110201650A1,6,COc1ccc(-n2nc(C3(COCc4ccccc4)CCC4(CC3)OCCO4)cc2-c2ccc(C)cc2)cc1>>COc1ccc(-n2nc(C3(COCc4ccccc4)CCC(=O)CC3)cc2-c2ccc(C)cc2)cc1 -US06410736B1,1,O=Cc1ccc(Br)cc1F.Oc1ccc(Cl)c(Cl)c1>>O=Cc1ccc(Br)cc1Oc1ccc(Cl)c(Cl)c1 -US03974156,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1CN(Cc2ccccc2)CCO1>>Cc1ccc(S(=O)(=O)OCC2CN(Cc3ccccc3)CCO2)cc1 -US07776875B2,2,CCCC(CCC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(Cl)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)O.CS(N)(=O)=O>>CCCC(CCC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(Cl)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)NS(C)(=O)=O -US20020032184A1,2,CCc1nn(CCN)c(CC)c1Cc1cc(Cl)cc(Cl)c1.Cn1cnc(S(=O)(=O)Cl)c1>>CCc1nn(CCNS(=O)(=O)c2cn(C)cn2)c(CC)c1Cc1cc(Cl)cc(Cl)c1 -US06432950B1,1,Cc1sc2nc(Cl)nc(NCc3ccccc3)c2c1C.c1nc[nH]n1>>Cc1sc2nc(-n3cncn3)nc(NCc3ccccc3)c2c1C -US20100068301A1,1,CC(C)C(=O)N1CCC[C@H]1COc1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n2Cc1ccc(Cl)cc1.O=[N+]([O-])OCCCCCCBr>>CC(C)C(=O)N1CCC[C@H]1COc1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)OCCCCCCO[N+](=O)[O-])n2Cc1ccc(Cl)cc1 -US20100249165A1,7,C#COC(=O)NC(=O)c1cc2ccccc2s1>>CCOC(=O)NC(=O)c1cc2ccccc2s1 -US20020193560A1,1,BrC1CCCCC1.CC(=O)N1CCN(c2ccc(O)cc2)CC1>>CC(=O)N1CCN(c2ccc(OC3CCCCC3)cc2)CC1 -US20150094339A1,6,COC(=O)[C@H](COC[C@H](Cc1ccc(C)cc1)[C@@H](OCC(C)C)[C@H](C)O)NC(=O)OC(C)(C)C>>Cc1ccc(C[C@@H](COC[C@H](NC(=O)OC(C)(C)C)C(=O)O)[C@@H](OCC(C)C)[C@H](C)O)cc1 -US07560558B2,1,COc1cc2c(Oc3cc(C)c(C)nc3-c3ccccn3)ccnc2cc1O.OCCBr>>COc1cc2c(Oc3cc(C)c(C)nc3-c3ccccn3)ccnc2cc1OCCO -US07994203B2,7,Cc1nn2c(-c3ccc(Cl)cc3Cl)c(C)oc2c1[N+](=O)[O-]>>Cc1nn2c(-c3ccc(Cl)cc3Cl)c(C)oc2c1N -US20110237588A1,8,CCC(C)n1cc(-c2ccncc2)c(-c2ccc(Cl)s2)n1.O=C(OO)c1cccc(Cl)c1>>CCC(C)n1cc(-c2cc[n+]([O-])cc2)c(-c2ccc(Cl)s2)n1 -US20070129416A1,6,CC(C)(C)OC(=O)N1CCN(C2CCN(C(=O)OCC3c4ccccc4-c4ccccc43)CC2)CC1>>CC(C)(C)OC(=O)N1CCN(C2CCNCC2)CC1 -US20090118169A1,2,CC(C)CC=C1CCC2(CC1)N[C@@H](C(=O)O)CS2.CC(C)CCC(=O)Cl>>CC(C)CC=C1CCC2(CC1)SC[C@H](C(=O)O)N2C(=O)CCC(C)C -US04962120,2,CC(C)(C)NCCCN.CCOC(=O)Cn1cnc(-c2ccccc2)c1-c1ccccc1>>CC(C)(C)NCCCNC(=O)Cn1cnc(-c2ccccc2)c1-c1ccccc1 -US20120184562A1,2,CN1CCN(c2cc3[nH]c(=O)c(C(=O)O)cc3cn2)CC1.COC(=O)c1ccc(Cl)c(N)c1>>COC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(N4CCN(C)CC4)cc3[nH]c2=O)c1 -US05994378,1,CC(C)(C)c1csc(-c2cc3cc(O)ccc3o2)n1.CCOC(=O)C(C)Oc1c(CO)cccc1OC>>CCOC(=O)C(C)Oc1c(COc2ccc3oc(-c4nc(C(C)(C)C)cs4)cc3c2)cccc1OC -US05783605,2,CN.O=C(Cl)Cc1ccccc1>>CNC(=O)Cc1ccccc1 -US20050075394A1,1,BrCCCCCCBr.OCCOCc1ccccc1>>BrCCCCCCOCCOCc1ccccc1 -US20130053563A1,1,CC(C)(C)OC(=O)C(C)(C)C(=O)O.COc1cc(OCCO)c(F)c(C(Nc2ccc(C(N)=NC(=O)OCC(C)(C)C)cc2)c2nc(OCCl)n(-c3ncccn3)n2)c1>>COc1cc(OCCO)c(F)c([C@@H](Nc2ccc(C(N)=NC(=O)OCC(C)(C)C)cc2)c2nc(OCOC(=O)C(C)(C)C(=O)OC(C)(C)C)n(-c3ncccn3)n2)c1 -US06417203B1,2,COCCN(Cc1cccc(CCNc2ncc(C)n(CC(=O)O)c2=O)c1)C(=O)C(F)(F)F.Cc1c[nH]c2ccc(CN)cc12>>COCCN(Cc1cccc(CCNc2ncc(C)n(CC(=O)NCc3ccc4[nH]cc(C)c4c3)c2=O)c1)C(=O)C(F)(F)F -US20090042856A1,7,Cc1ccccc1-n1nc(-c2c(-c3ccc(F)cc3)nn3c2N(CCC(=O)O)CC3)ccc1=O>>Cc1ccccc1-n1nc(-c2c(-c3ccc(F)cc3)nn3c2N(CCCO)CC3)ccc1=O -US09156827B2,6,COc1ccc2c(c1CCCCN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O>>COc1ccc2c(c1CCCCN1CCNCC1)O/C(=C\c1n[nH]c3ccccc13)C2=O -US04762829,2,CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC(=O)O.c1c[nH]cn1>>CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC(=O)n1ccnc1 -US20110112120A9,1,CCCc1nc(COC)cc(=O)[nH]1.N#Cc1ccccc1-c1ccc(CBr)cc1>>CCCc1nc(COC)cc(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US08034812B2,2,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.Cn1nccc1C(=O)O>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1NC(=O)c1ccnn1C -US20140194412A1,1,COc1cc(C=O)ccc1O.OB(O)c1ccccc1>>COc1cc(C=O)ccc1Oc1ccccc1 -US08993756B2,7,O=[N+]([O-])c1cccc(-c2ncnc3[nH]cc(Br)c23)c1>>Nc1cccc(-c2ncnc3[nH]cc(Br)c23)c1 -US20020115853A1,3,O=C1CSc2cc(Br)ccc2N1.O=[N+]([O-])c1cccc(B(O)O)c1>>O=C1CSc2cc(-c3cccc([N+](=O)[O-])c3)ccc2N1 -US08258134B2,1,O=C(Nc1cnccn1)C(Br)CC1CCCC1.O=c1cc(Oc2ccccc2C(F)(F)F)cn[nH]1>>O=C(Nc1cnccn1)C(CC1CCCC1)n1ncc(Oc2ccccc2C(F)(F)F)cc1=O -US20100179216A1,7,Cc1cc(C)cc(C#CCO)c1>>Cc1cc(C)cc(CCCO)c1 -US20020173526A1,1,ICCCc1cccc(OCc2ccccc2)c1.OCC(O)Cc1ncc[nH]1>>OCC(O)Cc1nccn1CCCc1cccc(OCc2ccccc2)c1 -US20090197897A1,2,Cc1sccc1C(=O)O.Fc1ccc(-c2noc([C@H]3CCCNC3)n2)cc1>>Cc1sccc1C(=O)N1CCC[C@H](c2nc(-c3ccc(F)cc3)no2)C1 -US04791129,2,COC(=O)C1C(=O)Nc2ccc(Cl)cc21.O=C=Nc1ccccc1>>COC(=O)C1C(=O)N(C(=O)Nc2ccccc2)c2ccc(Cl)cc21 -US20130109661A1,3,Nc1ccc(Cl)nn1.OB(O)c1ccccc1>>Nc1ccc(-c2ccccc2)nn1 -US20130109668A1,2,CC(C)(C)OC(=O)N1CCC12CNC2.O=C=NCCCc1ccccc1>>CC(C)(C)OC(=O)N1CCC12CN(C(=O)NCCCc1ccccc1)C2 -US20150158865A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nnc(C(N)=O)c(Nc3ccc(C(=O)N4CCOCC4)cc3)n2)C1>>NC(=O)c1nnc(N[C@@H]2CCCNC2)nc1Nc1ccc(C(=O)N2CCOCC2)cc1 -US06703392B2,1,COc1cc(Cl)nc(OC)n1.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NC1CCc3ccccc31)CC2>>COc1cc(Oc2cc3c(cc2OC)CCN(CC(=O)NC2CCc4ccccc42)C3Cc2ccc(OC)c(OC)c2)nc(OC)n1 -US08088936B2,3,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(OCC)c2)c1CCC(=O)OCC.OB(O)c1cncnc1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(OCC)cc(-c3cncnc3)c2)c1CCC(=O)OCC -US20110269712A1,6,CCOC(=O)c1csc(N2CCN(C(=O)OC(C)(C)C)CC2)n1>>CCOC(=O)c1csc(N2CCNCC2)n1 -US20130065876A1,6,CN1CCN(NC(=O)OC(C)(C)C)CC1=O>>CN1CCN(N)CC1=O -US20060069093A1,2,CCOC(=O)NS(=O)(=O)c1ccc(Cl)s1.CNc1cc2c(cc1Cl)C(=O)N(c1ccc(N)cc1)CO2>>CNc1cc2c(cc1Cl)C(=O)N(c1ccc(NC(=O)NS(=O)(=O)c3ccc(Cl)s3)cc1)CO2 -US04888044,2,CCNc1ccccc1.O=C(O)COc1cc(C(F)(F)F)no1>>CCN(C(=O)COc1cc(C(F)(F)F)no1)c1ccccc1 -US06350759B1,1,CCI.Cc1cc([N+](=O)[O-])cc(C)c1O>>CCOc1c(C)cc([N+](=O)[O-])cc1C -US20140336232A1,4,Fc1ccc(C(=Cc2ccccc2Cl)CBr)c(F)c1.OO>>Fc1ccc(C2(CBr)OC2c2ccccc2Cl)c(F)c1 -US20110053931A1,2,COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCOCC1.O=C(O)c1cccn(-c2ccc(F)cc2)c1=O>>COc1cc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 -US20120220577A1,2,COC(=O)c1ccccc1N.O=C(Cl)CCl>>COC(=O)c1ccccc1NC(=O)CCl -US05919782,1,Clc1ccccn1.OC1CCNCC1>>OC1CCN(c2ccccn2)CC1 -US05510366,1,C=CCI.CCOC(=O)c1cc2c(O)cccc2[nH]1>>C=CCOc1cccc2[nH]c(C(=O)OCC)cc12 -US20030058697A1,3,C#Cc1ccccc1.Nc1ccc(C#Cc2ccc(Br)cc2[N+](=O)[O-])cc1>>Nc1ccc(C#Cc2ccc(C#Cc3ccccc3)cc2[N+](=O)[O-])cc1 -US20140080801A1,2,CS(=O)(=O)Cl.OCC1COC1>>CS(=O)(=O)OCC1COC1 -US20090286778A1,2,Cn1cncc1C(=O)Cl.O=C(C[C@@H]1CCNC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2>>Cn1cncc1C(=O)N1CC[C@@H](CC(=O)Nc2ccc3cc2CCc2cncc(c2)Nc2ncc(Cl)c(n2)N3)C1 -US04179569,2,Cc1ccc(S(=O)(=O)Cl)cc1.Cn1cccc1CCO>>Cc1ccc(S(=O)(=O)OCCc2cccn2C)cc1 -US20110046109A1,2,CCOC(=O)/C=C/c1c(Nc2c(F)cccc2F)nc(SC)nc1-c1ccc(F)cc1C>>CSc1nc(-c2ccc(F)cc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1 -US08927587B2,6,CC(C)(C)OC(=O)N[C@](C)(CO)c1nc2cc(C(C)(C)C)ccc2[nH]1>>CC(C)(C)c1ccc2[nH]c([C@](C)(N)CO)nc2c1 -US20120322788A1,1,CC(C)c1nc(C(=O)N2CCOC3(CCNCC3)C2)cs1.OCCc1cccc(CBr)c1>>CC(C)c1nc(C(=O)N2CCOC3(CCN(Cc4cccc(CCO)c4)CC3)C2)cs1 -US07714010B2,6,CC(C)(C)OC(=O)Nc1ccccc1CN1C(=O)C(C)(C)c2cc3nc(NC(=O)c4cccnc4)[nH]c3cc21>>CC1(C)C(=O)N(Cc2ccccc2N)c2cc3[nH]c(NC(=O)c4cccnc4)nc3cc21 -US04536577,1,Cc1ncc(C=O)c(N)n1.N>>Cc1ncc(CN)c(N)n1 -US08288549B2,1,NC(Cc1c[nH]c2ccccc12)C(=O)O.O=C(O)c1cc2cc(Cl)cc(Cl)c2nc1Cl>>O=C(O)c1cc2cc(Cl)cc(Cl)c2nc1NC(Cc1c[nH]c2ccccc12)C(=O)O -US20150274664A1,1,CC(C)(C)OC(=O)N1CCC([C@H]2C[C@@H]2CCN)CC1.CS(=O)(=O)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC([C@H]2C[C@@H]2CCNc2ccc(S(C)(=O)=O)cc2)CC1 -US20090012129A1,6,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\C)C(=O)OCC)cc2OCC)c1>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\C)C(=O)O)cc2OCC)c1 -US08058283B2,3,C#Cc1ccccc1C.COC(=O)c1nc(SC)ncc1Br>>COC(=O)c1nc(SC)ncc1C#Cc1ccccc1C -US08952169B2,1,CC(C)(C)OC(=O)c1cc(Cl)c(F)cc1F.CC1(CO)CCC2(CC1)OCCO2>>CC1(COc2cc(F)c(C(=O)OC(C)(C)C)cc2Cl)CCC2(CC1)OCCO2 -US06133303,6,COc1ccc2c(c1)NCCC2=O>>O=C1CCNc2cc(O)ccc21 -US20140213570A1,3,CN(c1ccc(Cl)nn1)C1CC(C)(C)NC(C)(C)C1.COc1cc2c(cc1B1OC(C)(C)C(C)(C)O1)CCC2=O>>COc1cc2c(cc1-c1ccc(N(C)C3CC(C)(C)NC(C)(C)C3)nn1)CCC2=O -US07071195B2,6,CCOC(=O)CN1CCC(n2c(=O)[nH]c3ccccc32)CC1>>O=C(O)CN1CCC(n2c(=O)[nH]c3ccccc32)CC1 -US07348425B2,1,C=O.COc1ccc2c(c1)C=C(C(=O)N1C[C@H](C)N[C@H](C)C1)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)NS(=O)(=O)N(C)C)cc21>>COc1ccc2c(c1)C=C(C(=O)N1C[C@H](C)N(C)[C@H](C)C1)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)NS(=O)(=O)N(C)C)cc21 -US20010046970A1,2,CCCCCCCCCCCCC#CC#CCCCCCCCCC(=O)O.NCCS(=O)(=O)O>>CCCCCCCCCCCCC#CC#CCCCCCCCCC(=O)NCCS(=O)(=O)O -US20130040983A1,2,CS(=O)(=O)Cl.C[Si](C)(C)CCOCn1c(-c2ccccc2)nc(-c2ccncc2)c1-c1cccc(N)c1>>C[Si](C)(C)CCOCn1c(-c2ccccc2)nc(-c2ccncc2)c1-c1cccc(NS(C)(=O)=O)c1 -US20090281139A1,6,CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc(C#N)cc3)C(=O)O)cc2)cc1CNC(=O)OC(C)(C)C>>CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc(C#N)cc3)C(=O)O)cc2)cc1CN -US08889638B2,2,O=S(=O)(Cl)c1ccccc1.O=c1cccccc1O>>O=c1cccccc1OS(=O)(=O)c1ccccc1 -US05081287,8,C=CCCCCCCCCCO>>C=CCCCCCCCCC=O -US20140303186A1,6,CCOC(=O)Cn1c(C)c(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c2ccccc21>>Cc1c(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c2ccccc2n1CC(=O)O -US07825216B2,10,Cc1ccc(C(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)C(C(=O)OC(C)(C)C)c1ccc(CBr)cc1 -US20110184177A1,1,COC(=O)C(C)(C)NC(=O)c1ccc2ccccc2c1O.OCc1cnc(Cl)c(Cl)c1>>COC(=O)C(C)(C)NC(=O)c1ccc2ccccc2c1OCc1cnc(Cl)c(Cl)c1 -US07192968B2,1,Brc1nc2c(s1)CNCC2.C=O>>CN1CCc2nc(Br)sc2C1 -US20040092510A1,7,CC(=O)N1N=C(c2ccc([N+](=O)[O-])c(Cl)c2)c2cc(Cl)c(Cl)cc2CC1C>>CC(=O)N1N=C(c2ccc(N)c(Cl)c2)c2cc(Cl)c(Cl)cc2CC1C -US07157604B2,2,CC(=O)Cl.CCCCC12CCC(=O)C(Br)=C1c1cc(F)c(N)c(Cl)c1C2>>CCCCC12CCC(=O)C(Br)=C1c1cc(F)c(NC(C)=O)c(Cl)c1C2 -US08367710B2,3,Brc1cccc(-c2nnn[nH]2)c1.COc1ccccc1B(O)O>>COc1ccccc1-c1cccc(-c2nnn[nH]2)c1 -US08372307B2,1,C=C(C)C(=O)O.CCCC1CCC(C(=O)OCCCCBr)CC1>>C=C(C)C(=O)OCCCCOC(=O)C1CCC(CCC)CC1 -US08138189B2,1,CCOC(=O)c1cc(B(O)O)ccc1Cl.Cc1cc(C(O)(C(C)c2ccc(O)cc2Cl)C(F)(F)F)cn(C)c1=O>>CCOC(=O)c1cc(Oc2ccc(C(C)C(O)(c3cc(C)c(=O)n(C)c3)C(F)(F)F)c(Cl)c2)ccc1Cl -US07135502B1,6,COc1cc2c(c(OC)c1OC)-c1ccc(NC(=O)[C@H](C)NC(=O)OCc3ccccc3)cc1C(NC(C)=O)CC2>>COc1cc2c(c(OC)c1OC)-c1ccc(NC(=O)[C@H](C)N)cc1C(NC(C)=O)CC2 -US20080249131A1,7,CCc1ccc([N+](=O)[O-])c2ccccc12>>CCc1ccc(N)c2ccccc12 -US05616579,2,CC(C)(C)C(=O)Cl.O=C(CSCCO)NC/C=C\COc1cc(CN2CCCCC2)ccn1>>CC(C)(C)C(=O)OCCSCC(=O)NC/C=C\COc1cc(CN2CCCCC2)ccn1 -US20100256156A1,3,Br[Mg]C1CCOCC1.Cc1oc(-c2ccccc2)cc1C=O>>Cc1oc(-c2ccccc2)cc1C(O)C1CCOCC1 -US06576766B1,2,CO.O=C(O)c1cc2cccc(O)c2cc1O>>COC(=O)c1cc2cccc(O)c2cc1O -US20100152177A1,2,O=Cc1c[nH]c2ncccc12.O=S(=O)(Cl)c1ccccc1>>O=Cc1cn(S(=O)(=O)c2ccccc2)c2ncccc12 -US20080200705A1,2,CCCCCCCC(=O)Br.CN(CC(=O)O)C(=N)N>>CCCCCCCC(=O)NC(=N)N(C)CC(=O)O -US20070049587A1,6,COC(=O)[C@@H]1C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C1>>COC(=O)[C@@H]1C[C@H](N)[C@@H](O)C1 -US20100204228A1,3,CCNS(=O)(=O)c1ccc(Br)cc1.Cn1c(C#N)ccc1B(O)O>>CCNS(=O)(=O)c1ccc(-c2ccc(C#N)n2C)cc1 -US04894385,1,COC(=O)c1ccc(S)cc1.Fc1ccc(C(Cl)Cn2ccnc2)cc1>>COC(=O)c1ccc(SC(Cn2ccnc2)c2ccc(F)cc2)cc1 -US05880157,2,CC1(C)C(C(=O)Cl)C1(C)C.Nc1ccccc1>>CC1(C)C(C(=O)Nc2ccccc2)C1(C)C -US04146645,7,CC(Cc1cccc([N+](=O)[O-])c1)NC(=O)CNCc1ccccc1>>CC(Cc1cccc(N)c1)NC(=O)CNCc1ccccc1 -US20090274650A1,1,CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(O)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2.OCCc1ccccc1>>CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(OCCc2ccccc2)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2 -US08048893B2,3,Brc1cn(CCN2CCCCC2)nc1OCc1ccccc1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cn(CCN3CCCCC3)nc2OCc2ccccc2)cc1 -US20100137610A1,9,CN(c1cccc2cc(C3=NCC(CC(=O)O)S3)[nH]c12)S(=O)(=O)c1cccs1.N>>CN(c1cccc2cc(C3=NCC(CC(N)=O)S3)[nH]c12)S(=O)(=O)c1cccs1 -US20140343053A1,2,Nc1cccnc1.O=C(O)c1cccc2nn(CCc3ccc4ccccc4n3)c(=O)n12>>O=C(Nc1cccnc1)c1cccc2nn(CCc3ccc4ccccc4n3)c(=O)n12 -US06337034B1,3,CCC[C@@H]1CC[C@@H](C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)CC1.N#Cc1ccc(C=O)cc1>>CCC[C@@H]1CC[C@@H](C=Cc2ccc(C#N)cc2)CC1 -US08349836B2,1,COc1ccc(OC)c(CN)c1.O=c1[nH]nc(Cl)c2cc(Br)ccc12>>COc1ccc(OC)c(CNc2ccc3c(=O)[nH]nc(Cl)c3c2)c1 -US07005443B1,6,CC(Cc1n[nH]c2ccc(OC(=O)C(C)C)cc12)NC(=O)OCC1c2ccccc2-c2ccccc21>>CC(N)Cc1n[nH]c2ccc(OC(=O)C(C)C)cc12 -US20070004736A1,2,Cc1ncc2n1C(=O)N(C1CCNCC1)C2.O=C(O)[C@H](O)CSc1ccc2cc(Cl)ccc2c1>>Cc1ncc2n1C(=O)N(C1CCN(C(=O)[C@H](O)CSc3ccc4cc(Cl)ccc4c3)CC1)C2 -US06884868B1,1,Brc1ccc(N2CCC(c3ccccc3)CC2)cc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N3CCC(c4ccccc4)CC3)cc2)CC1 -US07888349B2,1,CC(C)(C)OC(=O)NCC(O)CN.O=[N+]([O-])c1cnc2ccccc2c1Cl>>CC(C)(C)OC(=O)NCC(O)CNc1c([N+](=O)[O-])cnc2ccccc12 -US20080219921A1,1,C1CCNCC1.CCOC(=O)CBr>>CCOC(=O)CN1CCCCC1 -US04668697,5,CC(=O)c1ccc2ccsc2c1.OCCO>>CC1(c2ccc3ccsc3c2)OCCO1 -US20040002497A1,1,CC(C)(C)OC(=O)N1CCNCC1.COc1ccc(-c2cc(CCCOS(C)(=O)=O)c(=O)n(Cc3ccc(F)cc3)n2)cc1F>>COc1ccc(-c2cc(CCCN3CCN(C(=O)OC(C)(C)C)CC3)c(=O)n(Cc3ccc(F)cc3)n2)cc1F -US08889716B2,7,CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])c(Cl)c2)CC1>>CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2ccc(N)c(Cl)c2)CC1 -US20110166152A1,6,CCOC(=O)CSc1nc2ncc(-c3cn(Cc4cc(Cl)c(Cl)c(Cl)c4)nn3)nc2s1>>O=C(O)CSc1nc2ncc(-c3cn(Cc4cc(Cl)c(Cl)c(Cl)c4)nn3)nc2s1 -US20080275043A1,3,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@H](N2CCC(Cc3c(Cl)cc(OS(=O)(=O)C(F)(F)F)cc3Cl)C2=O)CC1.OB(O)c1ccncc1>>CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@H](N2CCC(Cc3c(Cl)cc(-c4ccncc4)cc3Cl)C2=O)CC1 -US07399761B2,6,COc1ncc(Cc2nnc(Nc3ccc(C(C)(C)C)cc3)c3ccccc23)cc1-c1ccco1>>CC(C)(C)c1ccc(Nc2nnc(Cc3cnc(O)c(-c4ccco4)c3)c3ccccc23)cc1 -US20120322769A1,2,CO.O=C(O)C=Cc1ccccc1>>COC(=O)C=Cc1ccccc1 -US20090209562A1,7,O=C1CCN(Cc2ccccc2)C1>>OC1CCN(Cc2ccccc2)C1 -US20120259123A1,7,CCCCC(C)(C)c1ccc(C=O)cc1>>CCCCC(C)(C)c1ccc(CO)cc1 -US07449490B2,6,CCOC(=O)c1c(C=Cc2ccc(C(C)C)cc2Cl)csc1N1C(=O)c2ccccc2C1=O>>CC(C)c1ccc(C=Cc2csc(N3C(=O)c4ccccc4C3=O)c2C(=O)O)c(Cl)c1 -US08193356B2,2,O=C(Cl)CCCCCCc1ccccc1.O=c1cc(O)c2cccnc2n1-c1ccccc1>>O=C(CCCCCCc1ccccc1)Oc1cc(=O)n(-c2ccccc2)c2ncccc12 -US08673906B2,1,CC(Br)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12.Nc1cccc(Cl)c1F>>CC(Nc1cccc(Cl)c1F)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 -US08822471B2,2,Clc1cnc(N2CCC(NC3CC3)CC2)nc1.O=C(O)c1ccc(-n2cncn2)cc1>>O=C(c1ccc(-n2cncn2)cc1)N(C1CC1)C1CCN(c2ncc(Cl)cn2)CC1 -US06825222B2,3,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccc(Br)cc3)oc2C)cc1.COc1ccc(B(O)O)cc1>>CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccc(-c4ccc(OC)cc4)cc3)oc2C)cc1 -US20070281955A1,1,Fc1ccc(-c2nc3sccn3c2-c2ccnc(NC3CCCNC3)n2)cc1.O=Cc1ccc(F)cc1>>Fc1ccc(CN2CCCC(Nc3nccc(-c4c(-c5ccc(F)cc5)nc5sccn45)n3)C2)cc1 -US07304071B2,1,CC[C@H](N)CO.COC(=O)c1ccc(-c2nc(Cl)ncc2Cl)cc1>>CCC(CO)Nc1ncc(Cl)c(-c2ccc(C(=O)OC)cc2)n1 -US20150152047A1,2,CCS(=O)(=O)c1ccc(Cl)cc1CN.O=C(O)c1cc(Cl)c(CO)c(C(F)(F)F)c1>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CO)c(C(F)(F)F)c1 -US20090264446A9,7,COC(=O)c1n[nH]cc1[N+](=O)[O-]>>COC(=O)c1n[nH]cc1N -US20100204225A1,1,COC(=O)Cc1c(C)[nH]c2ncccc12.Clc1ccc(I)cc1>>COC(=O)Cc1c(C)n(-c2ccc(Cl)cc2)c2ncccc12 -US04962234,1,CC(=O)c1ccccc1.CCCCCCCCCc1ccc(N)cc1>>CCCCCCCCCc1ccc(N=C(C)c2ccccc2)cc1 -US20120022059A1,6,CCOC(=O)c1cc(-c2cccc(Cl)c2)c(Br)o1>>O=C(O)c1cc(-c2cccc(Cl)c2)c(Br)o1 -US08618162B2,1,BrCC1CCCCC1.Oc1ccccc1O>>Oc1ccccc1OCC1CCCCC1 -US20120095011A1,1,Cc1cc(CN)on1.Cc1cc(Nc2nc(Cl)ncc2Br)n[nH]1>>Cc1cc(CNc2ncc(Br)c(Nc3cc(C)[nH]n3)n2)on1 -US20130172328A1,6,CC(C)n1c(=O)n(-c2ccc(OCc3ccccc3)cc2)c2ncc(Cl)cc21>>CC(C)n1c(=O)n(-c2ccc(O)cc2)c2ncc(Cl)cc21 -US07790763B2,2,CNS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)O)c1.FC(F)(F)c1ccc(OC2CCNC2)cc1>>CNS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)N2CCC(Oc3ccc(C(F)(F)F)cc3)C2)c1 -US20070173486A1,2,Clc1ccc(C(OC2CNC2)c2ccc(Cl)cc2Cl)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)N1CC(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2Cl)C1 -US04629586,2,CCC#CCCO.CCCC(=O)O>>CCC#CCCOC(=O)CCC -US20100210642A1,3,C#Cc1cnn2ccc(-c3ccc(Cl)cc3)nc12.NS(=O)(=O)c1ccc(Br)s1>>NS(=O)(=O)c1ccc(C#Cc2cnn3ccc(-c4ccc(Cl)cc4)nc23)s1 -US20100093705A1,2,CCc1c(CNC)oc2ccccc12.O=C(O)/C=C/c1cnc2c(c1)OCC(=O)N2>>CCc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)OCC(=O)N3)oc2ccccc12 -US20140275071A1,1,BrCCBr.Cn1c(=O)[nH]c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1>>Cn1c(=O)n(CCBr)c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1 -US20070037846A1,1,BrCC1CCC1.Cc1cc(C=O)ccc1O>>Cc1cc(C=O)ccc1OCC1CCC1 -US08188101B2,1,C=O.Cc1nccn1-c1ccc(Nc2nc3c(c(NCC4CCOCC4)n2)CNCC3)cc1>>Cc1nccn1-c1ccc(Nc2nc3c(c(NCC4CCOCC4)n2)CN(C)CC3)cc1 -US20100234351A1,1,CC(C)S(=O)(=O)c1cccc(Oc2ccc(N)cc2Cl)c1.COC(=O)C1=Cc2c(Cl)ncnc2NCC1>>COC(=O)C1=Cc2c(ncnc2Nc2ccc(Oc3cccc(S(=O)(=O)C(C)C)c3)c(Cl)c2)NCC1 -US06914058B2,1,C1COCCN1.O=[N+]([O-])c1cc(F)c(F)c(F)c1>>O=[N+]([O-])c1cc(F)c(N2CCOCC2)c(F)c1 -US04668697,9,NS(=O)(=O)c1cc2cc(CCBr)ccc2s1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCc1ccc2sc(S(N)(=O)=O)cc2c1 -US08232273B2,6,N#Cc1c(-c2ccc(OCc3ccccc3)cc2)csc1N>>N#Cc1c(-c2ccc(O)cc2)csc1N -US08193214B2,3,Cc1cccc2scc(C=O)c12.O=C1CN2C=CC=CC2=N1>>Cc1cccc2scc(C=C3C(=O)N=C4C=CC=CN34)c12 -US06066672,8,CC[C@H](C)[C@@H](CO)NC(=O)OC(C)(C)C>>CC[C@H](C)[C@@H](C=O)NC(=O)OC(C)(C)C -US20090156646A1,2,CC(C)(C)OC(=O)NCCC(=O)O.CCOCOc1cc(F)ccc1-c1cc(-c2cccc(N)c2)c(C#N)c(NC(=O)c2cccs2)n1>>CCOCOc1cc(F)ccc1-c1cc(-c2cccc(NC(=O)CCNC(=O)OC(C)(C)C)c2)c(C#N)c(NC(=O)c2cccs2)n1 -US20070219230A1,1,BrCc1ccccc1.Cc1cc2cc(C#N)nc(N3CCc4ccccc4C3)c2[nH]1>>Cc1cc2cc(C#N)nc(N3CCc4ccccc4C3)c2n1Cc1ccccc1 -US20100216767A1,1,CC(C)(C)OC(=O)NCCBr.O=[N+]([O-])c1cc(O)cc(Br)c1>>CC(C)(C)OC(=O)NCCOc1cc(Br)cc([N+](=O)[O-])c1 -US20100004222A1,6,COC(=O)c1cnc2cc(NC(=O)OCc3ccccc3)ccc2c1>>COC(=O)c1cnc2cc(N)ccc2c1 -US20110009454A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1cccc(Oc2cccc(I)c2)c1>>CC(C)(C)OC(=O)NCc1cccc(Oc2cccc(I)c2)c1 -US06265349B1,10,Cc1cc2c(-c3ccc(C(F)(F)F)n(C)c3=O)c(F)cc(Cl)c2o1.O=C1CCC(=O)N1Br>>Cn1c(C(F)(F)F)ccc(-c2c(F)cc(Cl)c3oc(CBr)cc23)c1=O -US04076840,2,CCCCCC(=O)Cl.CCOC1([NH3+])CC1>>CCCCCC(=O)NC1(OCC)CC1 -US04215121,9,CN(C)CCN(C(=O)N(C)C)c1ccc(Cl)nn1>>CN(C)CCN(C(=O)N(C)C)c1cccnn1 -US20130274469A1,2,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.c1cc2n(n1)CCCN2>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCCn3nccc32)cn1 -US20110052534A1,10,CCCOc1ccc(-c2ncc(CC(=O)OC)cn2)c(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>CCCOc1ccc(-c2ncc(C(Br)C(=O)OC)cn2)c(C(F)(F)F)c1 -US08288371B2,2,Cc1noc([C@H]2CCCN2)c1Cc1ccc(Cl)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>Cc1noc([C@H]2CCCN2C(=O)Nc2ccc(C(F)(F)F)cc2)c1Cc1ccc(Cl)cc1 -US20040044030A1,10,COc1ccc2c(=O)n(C)c(C)c(-c3ccccc3)c2c1.O=C1CCC(=O)N1Br>>COc1ccc2c(=O)n(C)c(CBr)c(-c3ccccc3)c2c1 -US20040138230A1,1,CN1C(=O)CC(C)(C)c2cc(CCCl)ccc21.c1ccc2c(N3CCNCC3)noc2c1>>CN1C(=O)CC(C)(C)c2cc(CCN3CCN(c4noc5ccccc45)CC3)ccc21 -US20130109682A1,6,CC(C)[Si](OC[C@H]1O[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]1O[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C>>CC(C)[Si](O[C@@H]1[C@@H](CO)O[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@H]1O[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C -US06465660B1,10,COc1cc2c(cc1OC)C(=O)OC2.O=C1CCC(=O)N1Br>>COc1cc2c(cc1OC)C(Br)OC2=O -US05545651,6,COc1ccccc1Oc1ccccc1>>Oc1ccccc1Oc1ccccc1 -US20110009622A1,1,Ic1ccccn1.O=C(O)c1cccc(S)c1>>O=C(O)c1cccc(Sc2ccccn2)c1 -US20110098286A1,1,COc1cc2ncnc(Cl)c2cc1OC.c1ccc(C2CNCCO2)cc1>>COc1cc2ncnc(N3CCOC(c4ccccc4)C3)c2cc1OC -US08188301B2,6,Fc1cc(F)cc(C2(F)CCN(Cc3ccccc3)C2)c1>>Fc1cc(F)cc(C2(F)CCNC2)c1 -US20110053949A1,1,CCOP(OCC)OCC.Clc1ccc(Oc2cccc(CBr)c2)nc1>>CCOP(=O)(Cc1cccc(Oc2ccc(Cl)cn2)c1)OCC -US20080064682A1,6,O=C1CN(Cc2ccccc2)CC(=O)N1>>O=C1CNCC(=O)N1 -US20130184256A1,2,COC(=O)C1CN1.O=C(O)c1ccc(Cl)s1>>COC(=O)C1CN1C(=O)c1ccc(Cl)s1 -US20060089356A1,2,Cn1c(C(=O)O)nc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1.NC1CCCCC1>>Cn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1 -US07329749B2,2,Fc1ccc(CCN2CCNCC2)cc1.O=C(O)c1cc2ccccc2cn1>>O=C(c1cc2ccccc2cn1)N1CCN(CCc2ccc(F)cc2)CC1 -US08183262B2,3,CC(C)(C)NS(=O)(=O)c1cccc(B(O)O)c1.FC(F)(F)c1cccc(-c2cc(C(F)(F)F)nc(-c3ccnc(Cl)c3)n2)c1>>CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4cccc(C(F)(F)F)c4)cc(C(F)(F)F)n3)ccn2)c1 -US20020188132A1,1,COC(=O)c1csc(Br)c1NS(=O)(=O)c1ccc(OC)cc1.ClCc1cccnc1>>COC(=O)c1csc(Br)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 -US20110212918A1,2,Nc1ccc2c(c1)B(O)OC2.O=[N+]([O-])c1cc(OCc2ccccc2)ccc1S(=O)(=O)Cl>>O=[N+]([O-])c1cc(OCc2ccccc2)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2 -US05958924,1,Nc1ccc2[nH]c(=O)cc(CCCl)c2c1.c1cc2sccc2c(N2CCNCC2)n1>>Nc1ccc2[nH]c(=O)cc(CCN3CCN(c4nccc5sccc45)CC3)c2c1 -US20140336198A1,1,CCC(N)c1ccc2c(c1)CC(C)O2.O=Cc1ccccn1>>CCC(NCc1ccccn1)c1ccc2c(c1)CC(C)O2 -US20090181942A1,7,COC(=O)CC1OC(c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(C=C(C)C)ccc21>>COc1cccc(C2OC(CCO)c3ccc(C=C(C)C)n3-c3ccc(Cl)cc32)c1OC -US08129406B2,2,N[C@@H]1CCCC[C@H]1C(=O)O.O=S(=O)(Cl)c1ccc(Oc2ccccc2)cc1>>O=C(O)[C@@H]1CCCC[C@H]1NS(=O)(=O)c1ccc(Oc2ccccc2)cc1 -US20110263571A1,2,Cc1cnc(N2CCNCC2)c(C)c1.O=C(O)c1ccc(Br)cn1>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)cn3)CC2)c(C)c1 -US05700836,3,CCCOc1cc2c(cc1C=O)C(C)(C)CCC2(C)C.CCOC(=O)c1ccc(CP(=O)(OCC)OCC)cc1>>CCCOc1cc2c(cc1/C=C/c1ccc(C(=O)OCC)cc1)C(C)(C)CCC2(C)C -US20150218092A1,1,COc1cc(N2CCC(Br)C2=O)ccc1OCOCC[Si](C)(C)C.Oc1ccc(-c2ccccc2)cc1>>COc1cc(N2CCC(Oc3ccc(-c4ccccc4)cc3)C2=O)ccc1OCOCC[Si](C)(C)C -US04628100,1,CN(C)CCCNc1ccccc1C(=O)c1ccccc1.Nc1cccnc1Cl>>CN(C)CCCNc1ccccc1C(=Nc1cccnc1Cl)c1ccccc1 -US20090042929A1,2,NCc1ccco1.O=C(O)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1>>O=C(NCc1ccco1)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1 -US06413938B1,7,Nc1c([N+](=O)[O-])cc(Cl)c(F)c1F>>Nc1cc(Cl)c(F)c(F)c1N -US20110281854A1,1,CC1CNC(c2ccccc2F)CO1.O=C1COc2ccc(Br)nc2N1>>C[C@H]1CN(c2ccc3c(n2)NC(=O)CO3)[C@@H](c2ccccc2F)CO1 -US06143764,2,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C=Nc1ccc(Br)cc1>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(Br)cc4)cc3)c2cc1OC -US20080176947A1,3,COCCCC(=O)Cl.Cc1ccc(Br)cc1>>COCCCC(=O)c1cc(Br)ccc1C -US20110112120A9,8,CCCc1nc(CC)n(-c2ccc(OC(C)(C)C(C)O)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1>>CCCc1nc(CC)n(-c2ccc(OC(C)(C)C(C)=O)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1 -US20070254882A1,6,CCOC(=O)CN(Cc1cccc(OCCc2nc(-c3cccs3)oc2C)c1)S(=O)(=O)N1CCCc2ccccc21>>Cc1oc(-c2cccs2)nc1CCOc1cccc(CN(CC(=O)O)S(=O)(=O)N2CCCc3ccccc32)c1 -US20100324020A1,6,Cn1cnc(C(=O)N(Cc2cccc(OC(F)(F)F)c2)CC2C3CN(CC(=O)OCc4ccccc4)CC32)c1>>Cn1cnc(C(=O)N(Cc2cccc(OC(F)(F)F)c2)CC2C3CN(CC(=O)O)CC32)c1 -US20120065195A1,3,CC(=O)Cc1ccc(Br)cc1.CCOC(=O)CC(=O)OCC>>CCOC(=O)C(C(=O)OCC)=C(C)Cc1ccc(Br)cc1 -US20150038488A1,3,CC1(C)OB(c2ccc(N3CC(N4CCOCC4)C3)cc2)OC1(C)C.C[C@@H](Oc1nc(Br)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1>>C[C@@H](Oc1nc(-c2ccc(N3CC(N4CCOCC4)C3)cc2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1 -US07645781B2,2,Cc1ccc(C)n1-c1ccc2c(c1)C[C@@H](C)N2.O=C(Cl)OCc1ccccc1>>Cc1ccc(C)n1-c1ccc2c(c1)C[C@@H](C)N2C(=O)OCc1ccccc1 -US06107297,1,COC(=O)CS.O=c1[nH]c(=O)n(-c2ccc(Cl)nn2)cc1C1c2ccccc2C=Cc2ccccc21>>COC(=O)CSc1ccc(-n2cc(C3c4ccccc4C=Cc4ccccc43)c(=O)[nH]c2=O)nn1 -US20150225367A1,6,CC(=O)NCCNS(=O)(=O)c1ccc(-c2cn(C(=O)OC(C)(C)C)c3cc(F)ccc23)cn1>>CC(=O)NCCNS(=O)(=O)c1ccc(-c2c[nH]c3cc(F)ccc23)cn1 -US08623877B2,1,Brc1cncnc1.C[C@H]1CCCN1[C@H]1CCN(c2ccc3c(c2)CCNC3)C1>>C[C@H]1CCCN1[C@H]1CCN(c2ccc3c(c2)CCN(c2cncnc2)C3)C1 -US05955464,1,Clc1ncnc2ccc(-n3ccnc3)cc12.Nc1ccc(F)c(F)c1>>Fc1ccc(Nc2ncnc3ccc(-n4ccnc4)cc23)cc1F -US05703243,2,COc1ccc(COC(=O)N2C[C@H](OS(C)(=O)=O)C[C@H]2CO)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(COC(=O)N2C[C@H](OS(C)(=O)=O)C[C@H]2COS(=O)(=O)c2ccc(C)cc2)cc1 -US05356922,2,C1CSCCN1.Cn1cnc(S(=O)(=O)Cl)c1>>Cn1cnc(S(=O)(=O)N2CCSCC2)c1 -US06048864,2,CC(=O)OC(C)=O.CS(=O)(=O)Nc1cccc2c1CCNC2>>CC(=O)N1CCc2c(cccc2NS(C)(=O)=O)C1 -US20140296246A1,3,Cc1noc(C)c1B1OC(C)(C)C(C)(C)O1.Nc1ccc(Br)cc1[N+](=O)[O-]>>Cc1noc(C)c1-c1ccc(N)c([N+](=O)[O-])c1 -US20050282864A1,7,O=C1CCN(CC2CC2)CC1>>OC1CCN(CC2CC2)CC1 -US20020028807A1,1,CCN1c2nc(F)ccc2NC(=O)c2cc(Br)cnc21.CI>>CCN1c2ncc(Br)cc2C(=O)N(C)c2ccc(F)nc21 -US20020002309A1,1,COC(=O)c1ccc(C(F)(F)F)cc1Cl.C[S-]>>COC(=O)c1ccc(C(F)(F)F)cc1SC -US20140378446A1,1,CC(C)(C)OC(=O)Nc1cc([N+](=O)[O-])ccc1O.COCCBr>>COCCOc1ccc([N+](=O)[O-])cc1NC(=O)OC(C)(C)C -US20120289520A1,9,Clc1cc(CBr)ccc1Br.[C-]#N>>N#CCc1ccc(Br)c(Cl)c1 -US20140349989A1,6,CCOC(=O)c1cn(CCCCCNC(=O)OC(C)(C)C)c2ccccc12>>CCOC(=O)c1cn(CCCCCN)c2ccccc12 -US20100087423A1,2,O=C(O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(F)cc2Cl)cc1.OC1CCNCC1>>O=C(NCC(=O)N1CCC(O)CC1)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(F)cc2Cl)cc1 -US20080139631A1,1,FC(F)(F)c1cccc(-c2nc(CCl)no2)c1.N#Cc1ccc2[nH]ccc2c1C(F)(F)F>>N#Cc1ccc2c(ccn2Cc2noc(-c3cccc(C(F)(F)F)c3)n2)c1C(F)(F)F -US06855512B2,6,CC1(C)CCN(C2CC2)c2ccc(C#C[Si](C)(C)C)cc21>>C#Cc1ccc2c(c1)C(C)(C)CCN2C1CC1 -US06265423B1,8,CC(O)c1cc(Br)cs1>>CC(=O)c1cc(Br)cs1 -US20150157611A1,2,CCOC(=O)c1cn2cc(Br)ccc2n1.Cc1cc(C)c(CN)c(C)c1>>Cc1cc(C)c(CNC(=O)c2cn3cc(Br)ccc3n2)c(C)c1 -US20110112097A1,10,COC(=O)c1ccc(C(=O)c2ccccc2C)cc1.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(C(=O)c2ccccc2CBr)cc1 -US20110160206A1,8,O[C@@H]1CC[C@@H](N(Cc2ccccc2)Cc2ccccc2)CC1>>O=C1CCC(N(Cc2ccccc2)Cc2ccccc2)CC1 -US20150203480A1,1,COC1CNC1.Fc1ccc(Br)cn1>>COC1CN(c2ccc(Br)cn2)C1 -US20110275797A1,1,CC(C)(C)OC(=O)Nc1cccc(-c2ccc(C(=O)OC(C)(C)C)c([N+](=O)[O-])c2)c1.CCI>>CCN(C(=O)OC(C)(C)C)c1cccc(-c2ccc(C(=O)OC(C)(C)C)c([N+](=O)[O-])c2)c1 -US20150218181A1,2,COc1cc(C#N)ccc1N.O=CO>>COc1cc(C#N)ccc1NC=O -US20140088053A1,7,C[C@]12CC[C@@H]3c4ccc(C(N)=O)cc4CC[C@H]3[C@@H]1C/C(=C\c1cccc(C(N)=O)c1)[C@@H]2O>>C[C@]12CC[C@@H]3c4ccc(C(N)=O)cc4CC[C@H]3[C@@H]1C[C@H](Cc1cccc(C(N)=O)c1)[C@@H]2O -US20100093825A1,1,Fc1c(F)c(F)c(CBr)c(F)c1F.N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2>>N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)OCc3c(F)c(F)c(F)c(F)c3F)(CC1)CC2 -US20140375943A1,6,O=C(OCCOCc1ccccc1)c1ccc(-c2ccc(O)cc2)cc1>>O=C(OCCO)c1ccc(-c2ccc(O)cc2)cc1 -US05258529,3,C=C(Cl)CCl.O=Cc1ccccc1>>C=C(Cl)CC(O)c1ccccc1 -US06949542B2,2,CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1N.CCc1ncccc1-c1cccc(C(=O)CC(=O)OC(C)(C)C)c1>>CCc1ncccc1-c1cccc(C(=O)CC(=O)Nc2cc(C(F)(F)F)c(OCC(F)(F)F)cc2NC(=O)OC(C)(C)C)c1 -US20020114770A1,4,N#Cc1cccc(S(=O)(=O)N[C@H]2CC[C@@H](c3ccc(O)cc3O)CC2)c1.[N-]=[N+]=[N-]>>O=S(=O)(N[C@H]1CC[C@@H](c2ccc(O)cc2O)CC1)c1cccc(-c2nnn[nH]2)c1 -US20070197604A1,1,Cc1oc(-c2ccc(Br)cc2)nc1CCOS(C)(=O)=O.FC[C@@H]1CCNC1>>Cc1oc(-c2ccc(Br)cc2)nc1CCN1CC[C@@H](CF)C1 -US06316177B1,1,C=CC(OCCCO)c1ccccc1.Clc1ncnc2nc[nH]c12>>C=CC(OCCCOc1ncnc2nc[nH]c12)c1ccccc1 -US20060116393A1,4,COc1ccc(CCNC=O)cc1Br>>COc1cc2c(cc1Br)CCN=C2 -US20070219230A1,1,C=CCn1c(C)c(C)c2ccnc(C=O)c21.Nc1ccc(F)cc1>>C=CCn1c(C)c(C)c2ccnc(C=Nc3ccc(F)cc3)c21 -US20150087658A1,1,CC[C@H](N)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1.Cc1noc(-c2c(N)ncnc2Cl)n1>>CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 -US06080861,6,COC(=O)c1sc(C(F)(F)F)cc1OCc1ccccc1>>O=C(O)c1sc(C(F)(F)F)cc1OCc1ccccc1 -USRE039916E1,6,COC(=O)COc1cc(OC)c(S(=O)Cc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1C>>COc1cc(OCC(=O)O)c(C)cc1S(=O)Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US20090286791A1,2,CCOc1ccc(C(=O)NCCN)cc1.O=C(O)c1c[nH]nc1C(F)(F)F>>CCOc1ccc(C(=O)NCCNC(=O)c2c[nH]nc2C(F)(F)F)cc1 -US20100286396A1,7,CCC1(CC)c2c(ccc(OC)c2OC)C(C)=C2c3cc4c(cc3CCN21)OCO4>>CCC1(CC)c2c(ccc(OC)c2OC)C(C)C2c3cc4c(cc3CCN21)OCO4 -US08334287B2,1,COCCBr.Cc1nc(C#Cc2cccc(Cl)c2)c(C)n1-c1cc[nH]c(=O)c1>>COCCn1ccc(-n2c(C)nc(C#Cc3cccc(Cl)c3)c2C)cc1=O -US20040198793A1,4,COC(=O)Cn1c(C(=O)NC(N)=S)cc2cc(C)cc(C)c21.COc1ccc(OC)c(C(=O)C(Br)CC2CCCCC2)c1>>COC(=O)Cn1c(C(=O)Nc2nc(-c3cc(OC)ccc3OC)c(CC3CCCCC3)s2)cc2cc(C)cc(C)c21 -US07560569B2,2,N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2.Nc1ccc(C=Cc2ccccc2)cc1>>N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)Nc3ccc(C=Cc4ccccc4)cc3)(CC1)CC2 -US06090805,2,CN(C)C(=O)Cl.O=C(Cc1ccc(OC2CCNCC2)cc1OCC(F)(F)F)N1CCC(N2C(=O)OCc3ccccc32)CC1>>CN(C)C(=O)N1CCC(Oc2ccc(CC(=O)N3CCC(N4C(=O)OCc5ccccc54)CC3)c(OCC(F)(F)F)c2)CC1 -US04975454,3,CCOC(=O)CP(=O)(OCC)OCC.COC(OC)C(C)=O>>CCOC(=O)C=C(C)C(OC)OC -US20120022075A1,6,COC[C@H](C)Oc1cc(Br)cc(OC)c1>>COC[C@H](C)Oc1cc(O)cc(Br)c1 -US20090182140A1,8,COc1cccc(C(O)c2cnc(SC)nc2Cl)c1>>COc1cccc(C(=O)c2cnc(SC)nc2Cl)c1 -US04232163,2,CN=C=O.NC1=NC(=CCC(=O)Nc2ccc(Cl)cc2)CS1>>CNC(=O)NC1=NC(=CCC(=O)Nc2ccc(Cl)cc2)CS1 -US20090221645A1,6,Cc1cccc2c(C(=O)OC(C)(C)C)cccc12>>Cc1cccc2c(C(=O)O)cccc12 -US20040214808A1,1,COc1ccc(-n2nc(C#N)c3c2C(=O)N(CCCCCl)CC3)cc1.O=C1CCCCN1>>COc1ccc(-n2nc(C#N)c3c2C(=O)N(CCCCN2CCCCC2=O)CC3)cc1 -US04259336,2,CCOC(=O)C1=C(O)c2sc3ccccc3c2S(=O)(=O)N1C.Nc1cnccn1>>CN1C(C(=O)Nc2cnccn2)=C(O)c2sc3ccccc3c2S1(=O)=O -US20110076276A1,1,CCI.O=c1[nH]cc(C(F)(F)F)c(=O)[nH]1>>CCn1cc(C(F)(F)F)c(=O)[nH]c1=O -US20150038488A1,2,C[C@@H](Oc1nc(-c2ccc(N3CCNCC3)cc2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1.O=S(=O)(Cl)C1COC1>>C[C@@H](Oc1nc(-c2ccc(N3CCN(S(=O)(=O)C4COC4)CC3)cc2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1 -US20120101134A1,6,CCOC(=O)CCc1cccc(-c2noc(-c3cnc(OC(C)C)c(Cl)c3)n2)c1Cl>>CC(C)Oc1ncc(-c2nc(-c3cccc(CCC(=O)O)c3Cl)no2)cc1Cl -US20030087920A1,1,CC(C)c1ccc(S(N)(=O)=O)nc1.COc1ccccc1Oc1c(Cl)ncnc1Cl>>COc1ccccc1Oc1c(Cl)ncnc1NS(=O)(=O)c1ccc(C(C)C)cn1 -US20100087424A1,7,CCCCOC(=O)CCc1c(F)ccc2ccc(OC)nc12>>COc1ccc2ccc(F)c(CCCO)c2n1 -US20050054631A1,1,CC(C)(C)c1ccc(-n2c(Cl)c(C=O)c3ccccc32)cc1.CC1CN1>>CC1CN1c1c(C=O)c2ccccc2n1-c1ccc(C(C)(C)C)cc1 -US20100249124A1,6,CCN1C(=O)COc2ccc(C(O)(C(C)c3ccc(OC)cc3Cl)C(F)(F)F)cc21>>CCN1C(=O)COc2ccc(C(O)(C(C)c3ccc(O)cc3Cl)C(F)(F)F)cc21 -US07582775B2,1,CC(C)(C)C(=O)CBr.CCC(CC)(c1ccc(O)c(C)c1)c1cc2ccc(C(=O)OC)cc2s1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2ccc(C(=O)OC)cc2s1 -US20120108574A1,6,CC(=O)c1ccc(-c2nc3n(c2-c2ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc2)-c2cccnc2Nc2ccccc2-3)cc1>>CC(=O)c1ccc(-c2nc3n(c2-c2ccc(C4(N)CCC4)cc2)-c2cccnc2Nc2ccccc2-3)cc1 -US20140142083A1,1,COC(=O)c1cc(Cl)cc(N)c1C.O=C1CCC1>>COC(=O)c1cc(Cl)cc(NC2CCC2)c1C -US06949542B2,1,C1CCNC1.O=C1CC(c2cccc(-c3ccnc(CO)c3)c2)=Nc2cc(OCC(F)(F)F)c(C(F)(F)F)cc2N1>>O=C1CC(c2cccc(-c3ccnc(CN4CCCC4)c3)c2)=Nc2cc(OCC(F)(F)F)c(C(F)(F)F)cc2N1 -US20100041891A1,2,COCCN.O=C(O)c1ccnc(Cl)c1F>>COCCNC(=O)c1ccnc(Cl)c1F -US20050234061A1,2,CC(C)(CO)C(=O)O.CC(N)C(Cc1ccc(Cl)cc1)c1ccc(Cl)cc1>>CC(NC(=O)C(C)(C)CO)C(Cc1ccc(Cl)cc1)c1ccc(Cl)cc1 -US20140288123A1,2,CC(C)CC(Oc1ccccc1)c1ccc(C(=O)O)cc1.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(C(CC(C)C)Oc3ccccc3)cc2)c(O)n1 -US20140303161A1,3,N#CCC(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2)c2c(N)ncnc21.O=CC1CC1>>N#CC(=CC1CC1)C(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2)c2c(N)ncnc21 -US07638648B2,3,C#C[Si](C)(C)C.Cc1c(Br)cc(C(C)(C)C)c(OC(C)C)c1C=O>>Cc1c(C#C[Si](C)(C)C)cc(C(C)(C)C)c(OC(C)C)c1C=O -US08247556B2,7,CC(C)(C)OC(=O)N1CCN(Cc2cc([N+](=O)[O-])ccc2C(F)(F)C(F)(F)F)CC1>>CC(C)(C)OC(=O)N1CCN(Cc2cc(N)ccc2C(F)(F)C(F)(F)F)CC1 -US20130274475A1,2,CC(C)(C)OC(=O)NC1CCNCC1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)NC1CCN(C(=O)OCc2ccccc2)CC1 -US20130172339A1,2,Nc1cccc(-c2nnn[nH]2)c1.O=S(=O)(Cl)c1ccc(F)cc1Cl>>O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(F)cc1Cl -US07906653B2,1,CCc1ccc(-c2ccc(C(F)(F)F)c(Cl)n2)cc1.NCCCO>>CCc1ccc(-c2ccc(C(F)(F)F)c(NCCCO)n2)cc1 -US06667404B2,7,COC(=O)c1nc(C(C)C)cs1>>CC(C)c1csc(CO)n1 -US04431657,1,COC(=O)c1ccccc1S.N#CCCl>>COC(=O)c1ccccc1SCC#N -US09155727B2,1,CC(C)(C)OC(=O)N1CCC(c2n[nH]c(-c3cnc(N)c(-c4nnc(C(C)(C)C)o4)n3)n2)CC1.CCI>>CCn1nc(C2CCN(C(=O)OC(C)(C)C)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 -US08048909B2,1,CN.O=Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cc3ccccc3s2)c1>>CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2cc3ccccc3s2)c1 -US20140193707A1,1,BrCBr.CN1CCCC1>>C[N+]1(CBr)CCCC1 -US20080293706A1,3,CC1(C)OB(c2cncc(NS(=O)(=O)c3ccccc3)c2)OC1(C)C.O=C(Cc1ccccc1)Nc1cnc2ccc(Br)cc2n1>>O=C(Cc1ccccc1)Nc1cnc2ccc(-c3cncc(NS(=O)(=O)c4ccccc4)c3)cc2n1 -US04912231,3,O=C(O)[C@@H]1C[C@H](F)CN1C(=O)c1ccccc1Cl.c1ccccc1>>O=C(O)[C@@H]1C[C@@H](c2ccccc2)CN1C(=O)c1ccccc1Cl -US06982348B2,2,NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1cccc2ccccc12.O=C(Cl)c1ccc(C(F)(F)F)cc1>>O=C(NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1cccc2ccccc12)c1ccc(C(F)(F)F)cc1 -US20040157741A1,2,Cc1ccc(C(=N)N)cc1F.O=S(=O)(Cl)c1ccc(F)c(Cl)c1>>Cc1ccc(C(=N)NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1F -US07683064B2,3,Cc1c(Br)cccc1N1CCc2cc(N(C)C)ccc2C1=O.Cn1cc(B2OC(C)(C)C(C)(C)O2)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O>>Cc1c(-c2cc(Nc3ccc(C(=O)N4CCOCC4)cn3)c(=O)n(C)c2)cccc1N1CCc2cc(N(C)C)ccc2C1=O -US07649001B2,1,N#Cc1ccc(F)c2ccccc12.OC[C@@H]1CCCNC1>>N#Cc1ccc(N2CCC[C@@H](CO)C2)c2ccccc12 -US20110172245A1,2,N#CC1(c2cccc(C(=O)O)c2)CC1.Nc1cccc(Oc2ccc([N+](=O)[O-])cc2)c1>>N#CC1(c2cccc(C(=O)Nc3cccc(Oc4ccc([N+](=O)[O-])cc4)c3)c2)CC1 -US20090042854A1,7,C[C@@H](O[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](/C=C/C(=O)OC(C)(C)C)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](CCC(=O)OC(C)(C)C)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US05965743,3,CCOP(=O)(Cc1ccccc1)OCC.O=Cc1ccc(-n2ccnc2)cc1>>C(=Cc1ccc(-n2ccnc2)cc1)c1ccccc1 -US20060166990A1,1,COC(=O)c1ccc(C)c(C(=O)c2ccc(N)cc2Cl)c1.Cc1c(F)cccc1Br>>COC(=O)c1ccc(C)c(C(=O)c2ccc(Nc3cccc(F)c3C)cc2Cl)c1 -US20140249126A1,8,CCn1cc(CO)c(=O)c2cc(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)c(F)c21>>CCn1cc(C=O)c(=O)c2cc(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)c(F)c21 -US20130237571A1,1,COC(=O)CCc1ccc(O)cc1.O=C(c1ccccc1)c1cccc(CBr)c1>>COC(=O)CCc1ccc(OCc2cccc(C(=O)c3ccccc3)c2)cc1 -US04735942,7,CCN1CCN(c2ccc([N+](=O)[O-])cc2)C1=O>>CCN1CCN(c2ccc(N)cc2)C1=O -US07579342B2,9,BrC(Br)Br.CCOC(=O)c1nc2c(N)nc(SCc3cccc(F)c3F)nc2[nH]c1=O>>CCOC(=O)c1nc2c(Br)nc(SCc3cccc(F)c3F)nc2[nH]c1=O -US06638929B2,1,COc1ccc2cc3ncc(C#N)c(Cl)c3cc2c1.Nc1ccc(Cl)cc1Cl>>COc1ccc2cc3ncc(C#N)c(Nc4ccc(Cl)cc4Cl)c3cc2c1 -US05891889,1,CI.Cc1ccccc1CC1(CO)CCN(C(=O)OC(C)(C)C)CC1>>COCC1(Cc2ccccc2C)CCN(C(=O)OC(C)(C)C)CC1 -US06982348B2,2,NC(Cc1ccc(CC(F)(F)C(F)(F)F)cc1)C(O)c1cccc(Cl)c1.O=C(O)c1cccc2c(Cl)cccc12>>O=C(NC(Cc1ccc(CC(F)(F)C(F)(F)F)cc1)C(O)c1cccc(Cl)c1)c1cccc2c(Cl)cccc12 -US05750549,7,CCOC(=O)c1sc(-c2ccncc2)nc1OC>>COc1nc(-c2ccncc2)sc1CO -US20140094465A1,4,CCCCCCN.O=C(O)c1ccc(C(=O)CCC(=O)c2ccc(O)cc2)cc1>>CCCCCCn1c(-c2ccc(O)cc2)ccc1-c1ccc(C(=O)O)cc1 -US20090163462A1,6,Cc1ccc(Oc2ccc(OC[C@H]3CCCN3C(=O)OC(C)(C)C)cc2)cc1>>Cc1ccc(Oc2ccc(OC[C@H]3CCCN3)cc2)cc1 -US20130109661A1,3,C[C@H]1CC[C@H](C)N1c1cccc(Nc2cc(Cl)nn3ccnc23)n1.OB(O)c1ccccc1>>C[C@H]1CC[C@H](C)N1c1cccc(Nc2cc(-c3ccccc3)nn3ccnc23)n1 -US20110092547A1,7,CCOC(=O)C1CCC(Oc2ccc([N+](=O)[O-])cn2)CC1>>CCOC(=O)C1CCC(Oc2ccc(N)cn2)CC1 -US20040147586A1,3,CCN(CC)CCOc1ccc2[nH]c(C=O)cc2c1.O=C1Cc2cc(-c3ccccc3)ccc2N1>>CCN(CC)CCOc1ccc2[nH]c(C=C3C(=O)Nc4ccc(-c5ccccc5)cc43)cc2c1 -US05998462,3,C=C[Sn](CCCC)(CCCC)CCCC.O=C(c1c[nH]c2ccc(Br)cc12)[C@H]1CCCN1C(=O)OCc1ccccc1>>C=Cc1ccc2[nH]cc(C(=O)[C@H]3CCCN3C(=O)OCc3ccccc3)c2c1 -US06242448B1,1,ClCc1oc(C2CCCCC2)nc1Cc1ccccc1.c1cc(N2CCNCC2)c2cc[nH]c2c1>>c1ccc(Cc2nc(C3CCCCC3)oc2CN2CCN(c3cccc4[nH]ccc34)CC2)cc1 -US20020028835A1,6,CCOC(=O)CNC(=O)c1ccc(N2CCC(NC[C@H](O)c3ccc(O)c(NS(C)(=O)=O)c3)CC2)cc1>>CS(=O)(=O)Nc1cc([C@@H](O)CNC2CCN(c3ccc(C(=O)NCC(=O)O)cc3)CC2)ccc1O -US04810713,1,COc1cc(C(C)=O)ccc1O.ClCCCCCBr>>COc1cc(C(C)=O)ccc1OCCCCCCl -US20030191323A1,2,Nc1ccccc1S(N)(=O)=O.O=C(O)c1ccc(C#Cc2ccccc2)cc1>>NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1 -US20150126449A1,6,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(-c5nccs5)cccc4nn23)CC1>>O=c1cc(C2CCNCC2)n2nc3cccc(-c4nccs4)c3c2[nH]1 -US20080096901A1,6,CCOC(=O)c1ccc(Nc2ncn(-c3ccnc(N4CC(C)N(C(C)=O)C(C)C4)c3)n2)cc1>>CC(=O)N1C(C)CN(c2cc(-n3cnc(Nc4ccc(C(=O)O)cc4)n3)ccn2)CC1C -US05389643,6,CC#CC(C)Oc1cc(NC(C)=O)c(Cl)cc1C(=O)OC>>CC#CC(C)Oc1cc(N)c(Cl)cc1C(=O)OC -US07169520B2,1,Ic1ccccc1.c1ccc2c(c1)Nc1ccccc1S2>>c1ccc(N2c3ccccc3Sc3ccccc32)cc1 -US05972984,7,COC(=O)[C@]1(O[SiH](C)C)C[C@H](C(C)(C)C)CN1C(=O)OC(C)(C)C>>C[SiH](C)O[C@]1(CO)C[C@H](C(C)(C)C)CN1C(=O)OC(C)(C)C -US07307094B2,2,CN1C2CCCC1CC(N)C2.COc1ccc(-c2nc3cccc(C(=O)O)c3o2)cc1>>COc1ccc(-c2nc3cccc(C(=O)NC4CC5CCCC(C4)N5C)c3o2)cc1 -US20050154007A1,1,CO.Cc1cccc(C)c1CNc1cccn2c(C)c(CCl)nc12>>COCc1nc2c(NCc3c(C)cccc3C)cccn2c1C -US20150210675A1,9,CCCCCCCCCCCCc1ccc(-c2nc(C3(C(=O)O)CC3)no2)cc1.N>>CCCCCCCCCCCCc1ccc(-c2nc(C3(C(N)=O)CC3)no2)cc1 -US20050176733A1,6,CCOC(=O)c1ccc(OCCCNC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>CCOC(=O)c1ccc(OCCCN)c([N+](=O)[O-])c1 -US20100234386A1,3,COc1ccccc1S(=O)(=O)N1CCN(c2cnc3ccc(Br)cc3n2)CC1.COc1ncc(Br)cc1NS(=O)(=O)C1CC1>>COc1ccccc1S(=O)(=O)N1CCN(c2cnc3ccc(-c4cnc(OC)c(NS(=O)(=O)C5CC5)c4)cc3n2)CC1 -US20060063817A1,6,COc1cccc2c1[nH]c(=O)n2CCCC(C)(C)NCC(O)c1cc(OCc2ccccc2)cc2c1OCC(=O)N2>>COc1cccc2c1[nH]c(=O)n2CCCC(C)(C)NCC(O)c1cc(O)cc2c1OCC(=O)N2 -US20060241112A1,1,Cc1ncc[nH]1.Fc1ccc(CNc2cncc(Cl)n2)cc1>>Cc1nccn1-c1cncc(NCc2ccc(F)cc2)n1 -US20130123235A1,2,CC(C)(C)OC(=O)c1c(N)ccc(-c2ccoc2C=O)c1O.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)c1c(NC(=O)OCc2ccccc2)ccc(-c2ccoc2C=O)c1O -US20040034034A1,6,COC(=O)c1ccc(COc2cc(Cl)ccc2OCC(=O)N2C[C@H](C)N(Cc3ccc(F)cc3)C[C@H]2C)nc1>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2OCc2ccc(C(=O)O)cn2)[C@H](C)CN1Cc1ccc(F)cc1 -US04888418,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=C1CCNCC1>>O=C1CCN(C(=O)C(F)(F)F)CC1 -US20150203479A1,6,N#Cc1ccc(-c2ccnn2C2CCCCO2)cc1[N+](=O)[O-]>>N#Cc1ccc(-c2ccn[nH]2)cc1[N+](=O)[O-] -US20020049240A1,1,CNCCO.Clc1ncccn1>>CN(CCO)c1ncccn1 -US08507483B2,2,Nc1cc(F)c(F)cc1O.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cc(F)c(F)cc1O -US20110020278A1,6,COC(=O)c1sc(C#CC(C)(C)C)cc1N[C@@H](C)CCO[Si](C)(C)C(C)(C)C>>COC(=O)c1sc(C#CC(C)(C)C)cc1N[C@@H](C)CCO -US20110306597A1,2,NCC1C(=O)Nc2ccccc21.O=C(O)c1ccc(-c2cc(F)cc(F)c2)nc1>>O=C(NCC1C(=O)Nc2ccccc21)c1ccc(-c2cc(F)cc(F)c2)nc1 -US20110257193A1,7,N#Cc1ccc(Nc2cc(Cl)ccc2[N+](=O)[O-])nc1>>N#Cc1ccc(Nc2cc(Cl)ccc2N)nc1 -US20140005175A1,2,CC(C)(C(=O)O)c1ccc(Br)cn1.NC1CCCCC1>>CC(C)(C(=O)NC1CCCCC1)c1ccc(Br)cn1 -US20060025445A1,9,CC(C)(Br)C(=O)c1ccccc1.[N-]=[N+]=[N-]>>CC(C)(N=[N+]=[N-])C(=O)c1ccccc1 -US07576086B2,1,COc1ccc2cc(C(=O)C(C)Br)ccc2c1Cl.Clc1cccc(N2CCNCC2)c1>>COc1ccc2cc(C(=O)C(C)N3CCN(c4cccc(Cl)c4)CC3)ccc2c1Cl -US03948946,5,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.SCCS>>CC(C)(C)c1cc(C2SCCS2)cc(C(C)(C)C)c1O -US20140171422A1,1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1CO[Si](C)(C)C(C)(C)C.CI>>CO[C@@H]1C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OC(C)(C)C)C1 -US05607939,2,NCC(CCO)(c1ccccc1)c1ccccc1.O=CO>>O=CNCC(CCO)(c1ccccc1)c1ccccc1 -US20060003183A1,3,CCOP(=O)(Cc1ccc(N(c2ccccc2C)c2ccccc2C)cc1)OCC.Cc1ccccc1N(c1ccc(C=O)cc1)c1ccccc1C>>Cc1ccccc1N(c1ccc(/C=C/c2ccc(N(c3ccccc3C)c3ccccc3C)cc2)cc1)c1ccccc1C -US20090203711A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(C(=O)OC2CCCC2)C1>>O=C(OC1CCCC1)C1CNCCN1C(=O)OCc1ccccc1 -US20140275049A1,6,COC(=O)c1ccc(-c2cc(-c3cc(C(C)(C)C)nc(C(C)(C)C)c3)n(-c3ccc(C(N)=O)cc3)n2)cc1>>CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)nn2-c2ccc(C(N)=O)cc2)cc(C(C)(C)C)n1 -US05587393,1,CCCCc1nc2ccc(N)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1.O=[N+]([O-])c1ccc(Cl)c2nonc12>>CCCCc1nc2ccc(Nc3ccc([N+](=O)[O-])c4nonc34)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20130303538A1,2,COC(=O)CC(=O)O.COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1>>COC(=O)CC(=O)O[C@@]1(C#Cc2cccc(C)c2)CCC[C@@H]2[C@H]1CCN2C(=O)OC -US06984649B1,2,CC(C)(C)OC(=O)NC1CCCC(C(=O)O)C1.CNOC>>CON(C)C(=O)C1CCCC(NC(=O)OC(C)(C)C)C1 -US04933355,3,CCOC(=O)C(=O)c1csc(NC(=O)Nc2ccc(OC)cc2)n1.O=C(O)CN1C(=O)CSC1=S>>CCOC(=O)C(=C1SC(=S)N(CC(=O)O)C1=O)c1csc(NC(=O)Nc2ccc(OC)cc2)n1 -US04581356,6,CC1NC(=O)NN=C1c1ccc2c(c1)CCC(=O)N2CCOCc1ccccc1>>CC1NC(=O)NN=C1c1ccc2c(c1)CCC(=O)N2CCO -US04010202,7,O=C1c2ccc(O)c(O)c2CCC1NC1CCCC1>>Oc1ccc2c(c1O)CCC(NC1CCCC1)C2O -US20150148349A1,2,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)O.NC1CCCCC1=O>>CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)NC1CCCCC1=O -US20100120785A1,1,C1CNCCN1.Clc1ncccc1Br>>Brc1cccnc1N1CCNCC1 -US20140065103A1,1,COC(=O)c1sc(C#CC(C)(C)C)cc1Br.COCC(N)COC>>COCC(COC)Nc1cc(C#CC(C)(C)C)sc1C(=O)OC -US07732446B1,2,COc1cc2c(C(=O)O)cnc(CNC(=O)OC(C)(C)C)c2cc1OC.COc1ccc(CN)cc1>>COc1ccc(CNC(=O)c2cnc(CNC(=O)OC(C)(C)C)c3cc(OC)c(OC)cc23)cc1 -US07576080B2,2,NN.O=C(O)c1cccc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1>>NNC(=O)c1cccc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1 -US04558040,1,C=CC(C)Cl.Cc1ccc([N+](=O)[O-])c(O)c1>>C=CC(C)Oc1cc(C)ccc1[N+](=O)[O-] -US20080081907A1,2,CNc1cccc2nc(NCc3ccc(C)o3)ccc12.O=S(=O)(Cl)c1ccc(F)cc1>>Cc1ccc(CNc2ccc3c(N(C)S(=O)(=O)c4ccc(F)cc4)cccc3n2)o1 -US08598154B2,6,CC(C)(C)[Si](C)(C)OCC1CC(OC2CCCCO2)C1>>OCC1CC(OC2CCCCO2)C1 -US04748239,7,COC(=O)C(C(=O)OC)C(Cc1c([N+](=O)[O-])cccc1C(F)(F)F)c1ccc(OC)cc1>>COC(=O)C(C(=O)OC)C(Cc1c(N)cccc1C(F)(F)F)c1ccc(OC)cc1 -US20100256097A1,7,CC(C)(C#N)c1ccc(-c2cc(C(N)=O)c([N+](=O)[O-])s2)cn1>>CC(C)(C#N)c1ccc(-c2cc(C(N)=O)c(N)s2)cn1 -US04518597,8,CC(=O)Nc1ccc(SCCCCOc2ccc3c(c2)C(C)(C)OC(=O)N3)cc1.OO>>CC(=O)Nc1ccc(S(=O)CCCCOc2ccc3c(c2)C(C)(C)OC(=O)N3)cc1 -US08217177B2,2,CNC.COc1ccc2c(OCc3nnc4ccc(-c5ccc(C(=O)Cl)s5)nn34)ccnc2c1>>COc1ccc2c(OCc3nnc4ccc(-c5ccc(C(=O)N(C)C)s5)nn34)ccnc2c1 -US08318757B2,10,Cc1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1Cl.O=C1CCC(=O)N1Br>>FC(F)(F)C1(c2cc(Cl)c(Cl)c(Cl)c2)CC(c2ccc(CBr)c(Cl)c2)=NO1 -US05451601,7,O=C1CCC(c2ccccc2)(c2ccccc2)C2C1CNC2C(=O)Cc1ccccc1>>O=C(Cc1ccccc1)C1NCC2C(O)CCC(c3ccccc3)(c3ccccc3)C12 -US06982348B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NC(Cc2cccc(SC(F)(F)F)c2)C(c2ccc(F)cc2)O1>>CC(C)(C)OC(=O)N1C(=O)OC(c2ccc(F)cc2)C1Cc1cccc(SC(F)(F)F)c1 -US06075039,1,Cc1nc(-c2ccc(Cn3c(=O)[nH]c4ccccc43)cc2)no1.ClCCBr>>Cc1nc(-c2ccc(Cn3c(=O)n(CCCl)c4ccccc43)cc2)no1 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)cn3)c(F)c2)OC1(C)C.CC[C@H](CO)NS(=O)(=O)c1ccccc1Br>>CC[C@H](CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 -US20110065702A1,3,CN1CCN(c2ccc(-c3n[nH]c4ccc(C=O)cc34)cn2)CC1.O=C1Cc2ccccc2N1>>CN1CCN(c2ccc(-c3n[nH]c4ccc(C=C5C(=O)Nc6ccccc65)cc34)cn2)CC1 -US20040116461A1,2,CN(C)CCCN.O=C(Cl)c1ccc(-n2nc3c4ccccc4[nH]c(C4CC4)c-3c2=O)cc1>>CN(C)CCCNC(=O)c1ccc(-n2nc3c4ccccc4[nH]c(C4CC4)c-3c2=O)cc1 -US20110003813A1,1,Cc1cc(Br)cnc1N1CCN[C@H](C)C1.Fc1ccc(-c2cc(Cl)nc(Cl)n2)cc1>>Cc1cc(Br)cnc1N1CCN(c2cc(-c3ccc(F)cc3)nc(Cl)n2)[C@H](C)C1 -US05652257,1,COC(=O)[C@@H]1CCC(=O)N1.O=[N+]([O-])c1ccc(CBr)cc1>>COC(=O)[C@@H]1CCC(=O)N1Cc1ccc([N+](=O)[O-])cc1 -US06972297B2,6,COC(=O)c1cnc(OC)nc1>>COc1ncc(C(=O)O)cn1 -US04946851,3,N#CC=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1C=O>>N#CC=Cc1ccccc1C=O -US20090062265A1,7,COC(=O)C(CN1CCC(NC(=O)OC(C)(C)C)CC1)c1c(F)ccc2ncc(OC)nc12>>COc1cnc2ccc(F)c(C(CO)CN3CCC(NC(=O)OC(C)(C)C)CC3)c2n1 -US08163793B2,1,N#CCNC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1.O=C1CCOCC1>>N#CCNC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1C1CCOCC1 -US20120114765A1,2,O=C(O)CNC(=O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1.OC1CCCNC1>>O=C(NCC(=O)N1CCCC(O)C1)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US05731315,3,Brc1cccnc1.OB(O)c1cccs1>>c1cncc(-c2cccs2)c1 -US07973047B2,7,COc1ccc(C(=O)OC[C@@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)cc1>>CC(C)(C)[Si](C)(C)OC[C@H](CO)O[Si](C)(C)C(C)(C)C -US20110003848A1,2,CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2N)cc1Cl)(C(C)C)C(C)C.O=C(Cl)Oc1ccccc1>>CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Oc2ccccc2)cc1Cl)(C(C)C)C(C)C -US06355662B1,2,CS(N)(=O)=O.Cc1ccccc1NC(=O)Nc1ccc(CC(=O)NC(CC(C)C)c2ncc(CCC(=O)O)s2)cc1>>Cc1ccccc1NC(=O)Nc1ccc(CC(=O)NC(CC(C)C)c2ncc(CCC(=O)NS(C)(=O)=O)s2)cc1 -US20120270875A1,6,C=CCOc1cccc(CCCCc2nc(C)c(C(=O)OCC)c(C)n2)c1>>C=CCOc1cccc(CCCCc2nc(C)c(C(=O)O)c(C)n2)c1 -US07253165B2,1,Fc1ccc2c(-c3ccc(OCCCBr)cc3)noc2c1.NCc1ccc(F)c(F)c1>>Fc1ccc2c(-c3ccc(OCCCNCc4ccc(F)c(F)c4)cc3)noc2c1 -US07935721B2,9,CCCCCCN1C(=O)C(O)(c2cc3c(cc2O)OCO3)c2ccccc21>>CCCCCCN1C(=O)C(c2cc3c(cc2O)OCO3)c2ccccc21 -US20110201604A1,7,CNc1ccc(S(C)(=O)=O)cc1[N+](=O)[O-]>>CNc1ccc(S(C)(=O)=O)cc1N -US04863920,3,CC(=O)C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.CN1Cc2c(C=O)ncn2-c2cccc(Cl)c2C1=O>>CC(=O)/C=C/c1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2 -US20070066624A1,1,Brc1nccs1.CC(C)(C)OC(=O)N1CCC(N2C(=O)NC[C@H]2c2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCC(N2C(=O)N(c3nccs3)C[C@H]2c2ccccc2)CC1 -US20060084643A1,1,C=O.COCC[C@H]1CN(C2=Nc3ccccc3Nc3ccc(C)cc32)CCN1>>COCC[C@H]1CN(C2=Nc3ccccc3Nc3ccc(C)cc32)CCN1C -US20100010053A1,3,CN(C)C=O.N#Cc1cccc2cc[nH]c12>>N#Cc1cccc2c(C=O)c[nH]c12 -US05061730,6,CCOC(=O)C(C(=O)OCC)C(CC(=O)OCc1ccccc1)c1ccccc1>>CCOC(=O)C(C(=O)OCC)C(CC(=O)O)c1ccccc1 -US20140364432A1,1,Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CN)c(-c2ccc(F)cc2)s1.FC(F)(F)c1ccc(Cl)nc1>>Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(C(F)(F)F)cn2)c(-c2ccc(F)cc2)s1 -US07423051B2,1,COc1ccc(F)cc1C(=O)c1ccc(Cl)nc1N.NC1CCN(Cc2ccccc2)CC1>>COc1ccc(F)cc1C(=O)c1ccc(NC2CCN(Cc3ccccc3)CC2)nc1N -US20120295897A1,1,COCCOCCBr.COc1ccc(OC)c2c1NC(=O)C2=O>>COCCOCCN1C(=O)C(=O)c2c(OC)ccc(OC)c21 -US20100216746A1,9,Fc1cc(Br)cc(Oc2c(Cl)ccc(CBr)c2F)c1Cl.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc(Cl)c(Oc2cc(Br)cc(F)c2Cl)c1F -US20150166558A1,1,CC(C)(C)OC(=O)N[C@@H](Cn1c(=O)c2c(n(Cc3c(F)cccc3C(F)(F)F)c1=O)CCC21CCNCC1)c1ccccc1.Clc1cccc(CBr)c1>>CC(C)(C)OC(=O)N[C@@H](Cn1c(=O)c2c(n(Cc3c(F)cccc3C(F)(F)F)c1=O)CCC21CCN(Cc2cccc(Cl)c2)CC1)c1ccccc1 -US20150105373A1,9,CC(C)(C)OC(=O)NC(CC(N)=O)c1ccc(OC(F)(F)F)c(F)c1>>CC(C)(C)OC(=O)NC(CC#N)c1ccc(OC(F)(F)F)c(F)c1 -US20060089367A1,2,CCC(=O)Cl.Fc1cc2nc(COc3ccccc3)n(Cc3ccc(OC(F)(F)F)cc3)c2cc1N1CCNCC1>>CCC(=O)N1CCN(c2cc3c(cc2F)nc(COc2ccccc2)n3Cc2ccc(OC(F)(F)F)cc2)CC1 -US07005440B1,1,COCCOCOc1cccc(CO)c1.ClCc1ccccn1>>COCCOCOc1cccc(COCc2ccccn2)c1 -US20100234599A1,2,Cc1cc(C(F)(F)F)c(N)c(C)n1.O=C(Br)CBr>>Cc1cc(C(F)(F)F)c(NC(=O)CBr)c(C)n1 -US08415378B2,6,COC(=O)C1CCN(C(=O)OC)C(c2ccc(C(F)(F)F)c(F)c2)C1>>COC(=O)N1CCC(C(=O)O)CC1c1ccc(C(F)(F)F)c(F)c1 -US04333481,1,C=COCCCC.CC(=O)O>>CCCCOC(C)OC(C)=O -US08569535B2,2,CCOC(=O)C1(N)Cc2ccccc2C1.COc1cccc(C(=O)O)c1C>>CCOC(=O)C1(NC(=O)c2cccc(OC)c2C)Cc2ccccc2C1 -US20130079303A1,3,Cc1nc(Cl)c2ncn(C3CCCCO3)c2n1.OB(O)c1cccnc1F>>Cc1nc(-c2cccnc2F)c2ncn(C3CCCCO3)c2n1 -US20090029958A1,2,NCCN1CCC(O)CC1.O=C(O)c1c(Cl)cccc1Cl>>O=C(NCCN1CCC(O)CC1)c1c(Cl)cccc1Cl -US20150045351A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ccc2c3c1NC[C@@H]3CNCC2>>CC(C)(C)OC(=O)N1CCc2ccc(Cl)c3c2[C@H](CN3)C1 -US07351735B2,1,BrCc1cccc(Br)c1.C[S-]>>CSCc1cccc(Br)c1 -US06048878,7,CC(C)(C)OC(=O)N1CCC(F)(C#Cc2ccc(F)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(F)(CCc2ccc(F)cc2)CC1 -US20100226994A1,7,CCCCCCCCCCCCCCCC(=O)OC/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C>>CC1=C(/C=C/C(C)=C/C=C/C(C)=C/CO)C(C)(C)CCC1 -US20080027050A1,2,CC(=O)Cl.COc1cccc(CNC(=O)c2nc3scc(COCc4ccc(CO)cc4)c3c(=O)[nH]2)c1>>COc1cccc(CNC(=O)c2nc3scc(COCc4ccc(COC(C)=O)cc4)c3c(=O)[nH]2)c1 -US07375227B2,6,Cc1cc(NC(=O)NCCN2CCC(NC(=O)OC(C)(C)C)CC2)c2ccccc2n1>>Cc1cc(NC(=O)NCCN2CCC(N)CC2)c2ccccc2n1 -US20110059951A1,8,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1CCO>>C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1CC=O -US05019577,6,CCOC(CCc1c(N(C(C)=O)C(C)=O)nc(NC(C)=O)[nH]c1=O)OCC>>CC(=O)Nc1nc(N(C(C)=O)C(C)=O)c(CCC=O)c(=O)[nH]1 -US05179112,3,COC(=O)c1ccc(CBr)c(OC)c1.Cn1ccc2cc(NC(=O)OC3CCCC3)ccc21>>COC(=O)c1ccc(Cc2cn(C)c3ccc(NC(=O)OC4CCCC4)cc23)c(OC)c1 -US20060287338A1,7,CCOC(=O)/C=C/c1cncc(Cl)c1>>CCOC(=O)CCc1cncc(Cl)c1 -US20090203665A1,6,CC(C)(C)OC(=O)N1Cc2cc(Cl)c(N3CCCCC3)cc2C1>>Clc1cc2c(cc1N1CCCCC1)CNC2 -US20100069351A1,1,Cc1noc(-c2ccc(Cl)nn2)n1.O=C1OC2(CCNCC2)CN1c1cccc(F)c1>>Cc1noc(-c2ccc(N3CCC4(CC3)CN(c3cccc(F)c3)C(=O)O4)nn2)n1 -US08476434B2,2,Cc1cc(N)ccc1Oc1ncccc1-c1ccncn1.O=C(O)Cc1cccc(C(F)(F)F)c1>>Cc1cc(NC(=O)Cc2cccc(C(F)(F)F)c2)ccc1Oc1ncccc1-c1ccncn1 -US04024273,1,CN.O=C(c1ccc(OCCCCBr)cc1)c1c(-c2ccccc2)oc2ccccc12>>CNCCCCOc1ccc(C(=O)c2c(-c3ccccc3)oc3ccccc23)cc1 -US05959123,6,O=C(N[C@@H]1C(=O)N[C@@H]1Oc1ccccc1)OCc1ccccc1>>N[C@@H]1C(=O)N[C@@H]1Oc1ccccc1 -US04818273,1,CCO.Cc1cc(Cl)n2nc(S(=O)(=O)Nc3c(Cl)ccc(C)c3Cl)nc2n1>>CCOc1cc(C)nc2nc(S(=O)(=O)Nc3c(Cl)ccc(C)c3Cl)nn12 -US20090066224A1,1,Cc1ccc(I)cc1.c1ccc2c(c1)[nH]c1ccccc12>>Cc1ccc(-n2c3ccccc3c3ccccc32)cc1 -US08642585B2,3,Cc1cc(B2OC(C)(C)C(C)(C)O2)ccn1.Cc1cc(I)cc(C)c1Br>>Cc1cc(-c2cc(C)c(Br)c(C)c2)ccn1 -US05340833,3,CN(C)C=O.COc1cccc(F)c1>>COc1cccc(F)c1C=O -US20130059853A1,1,CC1(CBr)COC1.COc1ccc(-c2cccc3c2CCC3=O)c(O)c1OCC1CC1>>COc1ccc(-c2cccc3c2CCC3=O)c(OCC2(C)COC2)c1OCC1CC1 -US05830912,8,CC(O)c1cc(F)c(OCc2ccccc2)c(F)c1OCc1ccccc1>>CC(=O)c1cc(F)c(OCc2ccccc2)c(F)c1OCc1ccccc1 -US06380387B1,1,CCN(CC)CCCl.Cc1c(-c2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)c(=O)n(C)c(=O)n1C>>CCN(CC)CCOC(=O)[C@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)NC(=O)c1c(Cl)cccc1Cl -US05068325,1,Nc1nc2c(s1)CCNCC2.O=CC=Cc1cccnc1>>Nc1nc2c(s1)CCN(CC=Cc1cccnc1)CC2 -US20060160821A1,2,Cc1ccccc1C(NC(=O)Nc1ccc(Cl)cc1)C(=O)O.Nc1ccc(N2CCOCC2=O)cc1>>Cc1ccccc1C(NC(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(N2CCOCC2=O)cc1 -US20120197027A1,1,CN1CCN(CCCO)CC1.COc1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2cc1O>>COc1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2cc1OCCCN1CCN(C)CC1 -US20070197526A1,6,CCOC(=O)c1cc(C)nn1-c1ccc(OC)cc1>>CCOC(=O)c1cc(C)nn1-c1ccc(O)cc1 -US20090318385A1,8,COc1ccc(CO)c2cc(C3CC3)nn12>>COc1ccc(C=O)c2cc(C3CC3)nn12 -US05643958,7,CC(=O)[C@@H](C/C=C/c1ccc2ccccc2c1)c1ccc(Cl)cc1>>C[C@H](O)[C@@H](C/C=C/c1ccc2ccccc2c1)c1ccc(Cl)cc1 -US07696210B2,7,Cc1ccc([N+](=O)[O-])c(N)n1>>Cc1ccc(N)c(N)n1 -US08586614B2,6,CCOC(=O)CSc1cnc(NC(=O)N(CCc2ccccc2)c2cccc(NC(C)=O)c2)s1>>CC(=O)Nc1cccc(N(CCc2ccccc2)C(=O)Nc2ncc(SCC(=O)O)s2)c1 -US05342850,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(C2SC(=O)NC2=O)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc(C3SC(=O)NC3=O)cc2)cc1 -US05972965,6,O=C(N[C@H](CCCO)c1nc(-c2ccccc2)c(-c2ccccc2)o1)OCc1ccccc1>>N[C@H](CCCO)c1nc(-c2ccccc2)c(-c2ccccc2)o1 -US20150105366A1,8,CCc1nc2ccc(C(O)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1>>CCc1nc2ccc(C(=O)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 -US08173813B2,7,O=C1CCCc2cc([N+](=O)[O-])ccc2N1CCN1CCCCC1>>Nc1ccc2c(c1)CCCC(=O)N2CCN1CCCCC1 -US20110263571A1,2,O=C(O)c1ccc(Br)cc1F.c1cc(N2CCNCC2)ncc1C1CC1>>O=C(c1ccc(Br)cc1F)N1CCN(c2ccc(C3CC3)cn2)CC1 -US06716855B2,2,Nc1cccnc1NCC1CCN(c2ccncc2)CC1.O=C(O)c1ccc(Cl)s1>>O=C(Nc1cccnc1NCC1CCN(c2ccncc2)CC1)c1ccc(Cl)s1 -US06900215B2,3,CC1(C)COB(c2ccc(F)c(-n3cccc3)c2)OC1.FC(F)(F)c1ccn2c(Br)cnc2n1>>Fc1ccc(-c2cnc3nc(C(F)(F)F)ccn23)cc1-n1cccc1 -US04495187,1,CN.Clc1nc2ccccc2n2cnnc12>>CNc1nc2ccccc2n2cnnc12 -US20030105072A1,6,CCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C>>CCCCCCCCCCNC(=O)[C@@H]1CCCN1 -US20110269781A1,6,COc1nc2c(N)nc(OCC3CCCO3)nc2n1C1CCCCO1>>COc1nc2c(N)nc(OCC3CCCO3)nc2[nH]1 -US07572809B2,1,Cc1cc(Nc2cc3ccccc3c(Cl)n2)n[nH]1.Nc1cccc(Cl)c1>>Cc1cc(Nc2cc3ccccc3c(Nc3cccc(Cl)c3)n2)n[nH]1 -US20100144694A1,1,CC1(C)NN(C2CCCCCCC2)C1=O.Cc1cccc(C(=O)Cl)c1>>Cc1cccc(C(=O)N2N(C3CCCCCCC3)C(=O)C2(C)C)c1 -US07094789B2,6,CC(C)(C)OC(=O)NCc1cccc(CNS(=O)(=O)c2cccc3cnccc23)c1>>NCc1cccc(CNS(=O)(=O)c2cccc3cnccc23)c1 -US20100179216A1,3,C#CCO.N#Cc1ccc(I)cc1>>N#Cc1ccc(C#CCO)cc1 -US20110166164A1,7,COc1ccc(CC#N)c(C)c1>>COc1ccc(CCN)c(C)c1 -US20130012516A1,1,C1CNCCN1.Cc1c(Cl)nn2cc(-c3ccc(F)cc3)nc2c1C>>Cc1c(N2CCNCC2)nn2cc(-c3ccc(F)cc3)nc2c1C -US05807859,2,NC1c2ccccc2-c2[nH]c(=O)c3nccn3c21.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)NC1c2ccccc2-c2[nH]c(=O)c3nccn3c21 -US09150555B2,6,CCOC(=O)c1cnn(-c2cc(CC)cnc2Cl)c1C>>CCc1cnc(Cl)c(-n2ncc(C(=O)O)c2C)c1 -US20040097518A1,6,C[C@H](NC(=O)c1c(CN2CCN(CCC(=O)OC(C)(C)C)CC2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1>>C[C@H](NC(=O)c1c(CN2CCN(CCC(=O)O)CC2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1 -US20040132694A1,1,CN1CCN(C(=O)c2cccc(Nc3c(Cl)c(=O)c3=O)c2O)CC1.Nc1ccccc1Cl>>CN1CCN(C(=O)c2cccc(Nc3c(Nc4ccccc4Cl)c(=O)c3=O)c2O)CC1 -US20070123504A1,1,CC(C)(C)OC(=O)CBr.O=[N+]([O-])c1ccc(N2CCC(O)C2)nc1>>CC(C)(C)OC(=O)COC1CCN(c2ccc([N+](=O)[O-])cn2)C1 -US20050136444A1,1,N=C(N)NN.O=Cc1ccc(F)cc1F>>N=C(N)NN=Cc1ccc(F)cc1F -US05427779,6,COc1c2occc2cc2ccc(=O)oc12>>O=c1ccc2cc3ccoc3c(O)c2o1 -US06251900B1,1,C1COCCN1.Clc1cc(Cl)nc(-n2cnc3ccccc32)n1>>Clc1cc(N2CCOCC2)nc(-n2cnc3ccccc32)n1 -US06235731B1,6,CC(C)(C)OC(=O)N1CCC(CNC(=O)C2Cc3cnc4cccc(n34)S2)CC1>>O=C(NCC1CCNCC1)C1Cc2cnc3cccc(n23)S1 -US08431578B2,1,CC(C)N1CCN(C(=O)c2ccc(-c3cncc(-c4cc(Cl)nc(-c5ccccn5)n4)c3)cc2)CC1.CC(C)O>>CC(C)Oc1cc(-c2cncc(-c3ccc(C(=O)N4CCN(C(C)C)CC4)cc3)c2)nc(-c2ccccn2)n1 -US07674822B2,2,CC(=O)Cl.CCOC(=O)COc1c(C(=O)OC)sc2c1sc1c(NCC3CCCCC3)cccc12>>CCOC(=O)COc1c(C(=O)OC)sc2c1sc1c(N(CC3CCCCC3)C(C)=O)cccc12 -US05326868,2,CCOC(=O)c1[nH]c2ccccc2c1N.O=C(Cl)c1ccccc1>>CCOC(=O)c1[nH]c2ccccc2c1NC(=O)c1ccccc1 -US20080269239A1,1,CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2.Clc1ccc2oc3c(Cl)ncnc3c2c1>>CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1CN2c1ncnc2c1oc1ccc(Cl)cc12 -US08367710B2,3,COc1c(Br)cc(F)cc1[N+](=O)[O-].O=C(O)c1cccc(B(O)O)c1>>COc1c(-c2cccc(C(=O)O)c2)cc(F)cc1[N+](=O)[O-] -US04737458,7,Cc1c([N+](=O)[O-])c(=O)n(C)n1C>>Cc1c(N)c(=O)n(C)n1C -US06552069B1,9,C=CCCCCCC(CCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(C(=O)OCC)C(=O)OCC>>C=CCCCCCC(CCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)OCC -US20140303186A1,2,COC(=O)Cc1nn(Cc2ccc(N)cc2)c2ncccc12.O=C(Cl)c1ccc2ccccc2c1>>COC(=O)Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c2ncccc12 -US07786129B2,1,CCC1(CCCCCl)C(=O)Nc2c(Cl)cc(Cl)cc21.Clc1ccc(N2CCNCC2)cc1Cl>>CCC1(CCCCN2CCN(c3ccc(Cl)c(Cl)c3)CC2)C(=O)Nc2c(Cl)cc(Cl)cc21 -US20040063720A1,1,N#Cc1cnc(Cl)s1.Nc1ccnc(Cl)n1>>N#Cc1cnc(Nc2ccnc(Cl)n2)s1 -US20140171430A1,2,CCOc1ccc2ccccc2c1C(=O)O.c1ccc2nc(N3CC4CNCC4C3)cnc2c1>>CCOc1ccc2ccccc2c1C(=O)N1CC2CN(c3cnc4ccccc4n3)CC2C1 -US20050261290A1,1,CN(CCO)Cc1ccccc1.O=C(NC1C2CC3CC(C2)CC1C3)[C@H]1CCCN1>>CN(CCN1CCCC1C(=O)NC1C2CC3CC(C2)CC1C3)Cc1ccccc1 -US20060116382A1,6,CC(C)(C)OC(=O)N1CCC[C@@]2(CCN(c3ccccc3Cl)C2=O)C1>>O=C1N(c2ccccc2Cl)CC[C@@]12CCCNC2 -US20060160794A1,1,CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1Cl.c1cn[nH]c1>>CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-n1cccn1 -US20150191464A1,1,BrCc1ccccc1.C=CC1(O)COC1>>C=CC1(OCc2ccccc2)COC1 -US07544812B2,6,CCOC(=O)C(C)(C)Oc1ccc(OCCC2CN(Cc3ccc(OC)cc3)C(=O)N2C)cc1>>COc1ccc(CN2CC(CCOc3ccc(OC(C)(C)C(=O)O)cc3)N(C)C2=O)cc1 -US04552894,1,BrCc1ccccc1.OCc1cccc(OCCF)c1>>FCCOc1cccc(COCc2ccccc2)c1 -US20070082912A1,4,CC(=O)CCC(=O)c1cc(C)ccc1OCc1ccc(F)cc1.COC(=O)c1cc(N)cc(N2CCCCC2=O)c1>>COC(=O)c1cc(N2CCCCC2=O)cc(-n2c(C)ccc2-c2cc(C)ccc2OCc2ccc(F)cc2)c1 -US07452892B2,1,CN.O=c1[nH]nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)nc(Cl)n12>>CNc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c2n[nH]c(=O)n12 -US20020107266A1,2,CC(C)(C)OC(=O)N[C@@H](CCc1ccccc1)C(=O)O.CNOC>>CON(C)C(=O)C(CCc1ccccc1)NC(=O)OC(C)(C)C -US20070172385A1,7,O=C1CCSc2cc(Br)ccc21>>Brc1ccc2c(c1)SCCC2 -US20140275508A1,2,C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)Cn1cnc2c(N)ncnc21.O=C(Cl)c1ccccc1>>C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)Cn1cnc2c(NC(=O)c3ccccc3)ncnc21 -US20140296136A1,1,C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)O[C@@H]1CCC[C@H]1CCC=CCc1c(nc3ccccc3c1O)O2)C(=O)NS(=O)(=O)C1CC1.OCCN1CCCCC1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)O[C@@H]1CCC[C@H]1CCC=CCc1c(nc3ccccc3c1OCCN1CCCCC1)O2)C(=O)NS(=O)(=O)C1CC1 -US08324396B2,4,CC(C)(C)NS(=O)(=O)c1ccc(C(=O)CBr)cc1.NC(N)=S>>CC(C)(C)NS(=O)(=O)c1ccc(-c2csc(N)n2)cc1 -US08324216B2,2,CCc1cc(N2CCNCC2)ccc1Cl.Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O>>CCc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)ccc1Cl -US20090099214A1,7,N#CCc1ccccc1-c1ccccc1>>NCCc1ccccc1-c1ccccc1 -US05397801,3,Cc1ccc(S(=O)(=O)N(CC(=O)N(C)C)c2ccc(Cl)cc2C(=O)c2ccccc2Cl)cc1>>Cc1ccc(S(=O)(=O)N2c3ccc(Cl)cc3C(O)(c3ccccc3Cl)C2C(=O)N(C)C)cc1 -US20150051177A1,2,Nc1cccc(O)c1.O=C(O)c1ccc(S(=O)(=O)N2CCCc3ccccc32)cc1>>O=C(Nc1cccc(O)c1)c1ccc(S(=O)(=O)N2CCCc3ccccc32)cc1 -US07829584B2,9,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nccc2ccc(CBr)cc12.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nccc2ccc(CN=[N+]=[N-])cc12 -US05208331,8,OC(CCc1ccc(Cl)cc1)Cn1ccnc1>>O=C(CCc1ccc(Cl)cc1)Cn1ccnc1 -US20030105151A1,3,Cc1[nH]c(C=O)c(C)c1CCC(=O)O.O=C1Cc2ccc(N3CCOCC3)cc2N1>>Cc1[nH]c(C=C2C(=O)Nc3cc(N4CCOCC4)ccc32)c(C)c1CCC(=O)O -US20060270675A1,1,CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC.N#CBr>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](N(C#N)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC -US07153997B2,7,COc1c(C(C)C)cc(Oc2c(Cl)cc(C(=O)N(C)CC(=O)O)cc2Cl)cc1[N+](=O)[O-]>>COc1c(N)cc(Oc2c(Cl)cc(C(=O)N(C)CC(=O)O)cc2Cl)cc1C(C)C -US20070293532A1,1,Cc1ccc(CBr)c(C)c1.O=C1NC(=O)c2ccccc21>>Cc1ccc(CN2C(=O)c3ccccc3C2=O)c(C)c1 -US20130203986A1,1,CC(C)N.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CC(C)Nc1nc(Cl)ncc1[N+](=O)[O-] -US20120245169A1,9,BrC(Br)(Br)Br.Cc1cccc2cc(CO)n(C(C)C)c(=O)c12>>Cc1cccc2cc(CBr)n(C(C)C)c(=O)c12 -US20150246922A1,3,O=C1NCCn2c1cc1cc(F)cc(Br)c12.OB(O)c1ccncc1>>O=C1NCCn2c1cc1cc(F)cc(-c3ccncc3)c12 -US20080103164A1,2,Cc1ccc(C2NCCc3c2[nH]c2ccc(F)cc32)cc1.O=C(Cl)CCc1ccccc1>>Cc1ccc(C2c3[nH]c4ccc(F)cc4c3CCN2C(=O)CCc2ccccc2)cc1 -US20090143354A1,1,N#CC1CNC1.O=C(NCC1CCCCC1)c1c(Cl)ccc2nc(Cl)ccc12>>N#CC1CN(c2ccc3c(C(=O)NCC4CCCCC4)c(Cl)ccc3n2)C1 -US05308854,1,CCc1cc(N)c(=O)[nH]c1C.ClCc1nc2ccccc2s1>>CCc1cc(NCc2nc3ccccc3s2)c(=O)[nH]c1C -US20150246922A1,3,N#Cc1cc(Br)c2c(c1)cc1n2CCCNC1=O.OB(O)c1ccc(Cl)cc1F>>N#Cc1cc(-c2ccc(Cl)cc2F)c2c(c1)cc1n2CCCNC1=O -US20060058324A1,2,CC(C)(C)OC(=O)NC1CCC(O)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC1CCC(OS(C)(=O)=O)CC1 -US20040106600A1,1,ClCCCBr.O=C1CCCCN1>>O=C1CCCCN1CCCCl -US07361659B2,2,Nc1cc(S(=O)(=O)NCCO)sc1Cl.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>O=C(Nc1cc(S(=O)(=O)NCCO)sc1Cl)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12 -US05010195,1,C[O-].Cc1nc(Cl)c(Cl)c(Cl)n1>>COc1nc(C)nc(Cl)c1Cl -US20100016344A1,1,CNCCNc1ccnc(N)n1.Nc1nc(Cl)c2c(n1)-c1ccccc1CCC2>>CN(CCNc1ccnc(N)n1)c1nc(N)nc2c1CCCc1ccccc1-2 -US20140303248A1,1,COc1cc(N)c(Cl)cc1C(=O)OC1CC2CCC1(C)C2(C)C.O=Cc1cc(Cl)cc(Cl)c1O>>COc1cc(NCc2cc(Cl)cc(Cl)c2O)c(Cl)cc1C(=O)OC1CC2CCC1(C)C2(C)C -US09079891B2,3,Cn1nc(C(F)(F)F)cc1B(O)O.Nc1ncc(Br)s1>>Cn1nc(C(F)(F)F)cc1-c1cnc(N)s1 -US05728686,1,CP(C)(=O)CCl.O=c1[nH]c(=O)n(-c2ccccc2)c2ncn(Cc3ccccc3)c12>>CP(C)(=O)Cn1c(=O)c2c(ncn2Cc2ccccc2)n(-c2ccccc2)c1=O -US05098904,1,FC(F)(F)c1nccc(Cl)n1.O=C1CCC(=O)N1CC1CCNCC1>>O=C1CCC(=O)N1CC1CCN(c2ccnc(C(F)(F)F)n2)CC1 -US20060264460A1,1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=CC1CCOCC1>>N#Cc1cnc2ccc(NCC3CCOCC3)cc2c1Nc1ccc(F)c(Cl)c1 -US04267179,4,COc1ccc(N(CCCl)CCCl)cc1.Nc1ccc(-n2cccn2)cc1>>COc1ccc(N2CCN(c3ccc(-n4cccn4)cc3)CC2)cc1 -US20080319074A1,3,CCCCCCC(=O)c1ccc(C(=O)OC)cc1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCCC(=COC)c1ccc(C(=O)OC)cc1 -US20090105295A1,2,Cc1c(C)n2nnnc2c2nc(CCl)n(CCCCN)c12.O=C(OC(=O)c1ccccc1)c1ccccc1>>Cc1c(C)n2nnnc2c2nc(CCl)n(CCCCNC(=O)c3ccccc3)c12 -US07838543B2,2,CCCCc1ccc(C(=O)O)cc1.CN1CCC(N(C)c2nc3cc(N)ccc3o2)CC1>>CCCCc1ccc(C(=O)Nc2ccc3oc(N(C)C4CCN(C)CC4)nc3c2)cc1 -US20090137610A1,1,CC(C)CN1C(=O)NC2(CCN(C(=O)OC(C)(C)C)CC2)C1=O.FC(F)(F)Oc1ccc(CBr)cc1>>CC(C)CN1C(=O)N(Cc2ccc(OC(F)(F)F)cc2)C2(CCN(C(=O)OC(C)(C)C)CC2)C1=O -US06242644B1,8,CCOc1cc(CO)cc(CO)c1>>CCOc1cc(C=O)cc(CO)c1 -US20110105566A1,6,Cn1nnnc1C(=NOCc1cccc(C2OCCO2)n1)c1ccccc1>>Cn1nnnc1C(=NOCc1cccc(C=O)n1)c1ccccc1 -US07868001B2,9,COCCOc1cc(C#N)cc(-c2cn3nc(Cl)ccc3n2)c1>>COCCOc1cc(C#N)cc(-c2cn3ncccc3n2)c1 -US20130274244A1,2,CCOC(=O)c1cnc2cc(Cl)ccn12.Cc1nn(Cc2ccn(C(C)C)n2)c2cccc(N)c12>>Cc1nn(Cc2ccn(C(C)C)n2)c2cccc(NC(=O)c3cnc4cc(Cl)ccn34)c12 -US20070010670A1,7,O=C(c1cc(Cl)c(O)c(Cl)c1)N1CCOc2cc([N+](=O)[O-])ccc21>>Nc1ccc2c(c1)OCCN2C(=O)c1cc(Cl)c(O)c(Cl)c1 -US06307052B1,6,CCOC(=O)CCCN1CCC(O[C@@H](c2ccc(Cl)cc2)c2ccccn2)CC1>>O=C(O)CCCN1CCC(O[C@@H](c2ccc(Cl)cc2)c2ccccn2)CC1 -US20060149079A1,2,CCCCC(=O)Cl.COC(=O)[C@@H](NCc1ccc(-c2ccccc2C#N)cc1)C(C)C>>CCCCC(=O)N(Cc1ccc(-c2ccccc2C#N)cc1)[C@H](C(=O)OC)C(C)C -US05602153,1,BrCc1ccc(Br)nc1.CCCCc1n[nH]c(CCCC)n1>>CCCCc1nc(CCCC)n(Cc2ccc(Br)nc2)n1 -US04981861,7,CCOc1cc(COC(C)=O)ncc1C>>CCOc1cc(CO)ncc1C -US20050239797A1,2,CN1CCN(c2nccc3cc4c(cc23)NCC4)CC1.Cc1nc(C)c(C(=O)O)s1>>Cc1nc(C)c(C(=O)N2CCc3cc4ccnc(N5CCN(C)CC5)c4cc32)s1 -US07632834B2,6,CCCC1(CCC)OC(=O)N(CCC(C)(C)NCC(O)c2cc(OCc3ccccc3)cc3c2OCC(=O)N3)c2ccccc21>>CCCC1(CCC)OC(=O)N(CCC(C)(C)NCC(O)c2cc(O)cc3c2OCC(=O)N3)c2ccccc21 -US20020183285A1,6,CCOC(=O)Cc1ccc(C#Cc2ccc3c(c2)C(C)(C)CC(C)(C)O3)cc1F>>CC1(C)CC(C)(C)c2cc(C#Cc3ccc(CC(=O)O)c(F)c3)ccc2O1 -US08088815B2,2,CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12.CNC>>CN(C)C(=O)c1ccc(NC(=O)C2NC(CC(C)(C)C)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)cc1 -US20100016374A1,2,CC1CC(C)N(C[C@@H](N)c2ccccc2)C1.O=C(O)c1cccc(C(F)(F)F)c1Cl>>CC1CC(C)N(C[C@@H](NC(=O)c2cccc(C(F)(F)F)c2Cl)c2ccccc2)C1 -US08178699B2,6,COC(=O)c1sccc1NS(=O)(=O)c1cccc(-c2c(C)cccc2C)c1>>Cc1cccc(C)c1-c1cccc(S(=O)(=O)Nc2ccsc2C(=O)O)c1 -US05189211,1,COC(=O)CBr.Oc1c(F)cccc1F>>COC(=O)COc1c(F)cccc1F -US20080090860A1,3,CC(=O)c1cc2c(Br)cccc2n1S(=O)(=O)c1ccccc1.CCOP(=O)(CC(=O)OC)OCC>>COC(=O)C=C(C)c1cc2c(Br)cccc2n1S(=O)(=O)c1ccccc1 -US06784192B2,3,Brc1ccccc1OCC1CCCCC1.C#CC1CCN(Cc2ccccc2)CC1>>C(#CC1CCN(Cc2ccccc2)CC1)c1ccccc1OCC1CCCCC1 -US08901156B2,2,CC(C)(CN)c1cnc(-c2ccc(F)cc2)o1.O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1>>CC(C)(CNC(=O)c1cccc(-c2noc(C(F)(F)F)n2)c1)c1cnc(-c2ccc(F)cc2)o1 -US20120202856A1,6,COC(=O)c1onc(C(C)(C)C)c1C>>Cc1c(C(C)(C)C)noc1C(=O)O -US07482340B2,7,O=C1CC(c2cccc(O)c2)Oc2ccc(O)cc21>>Oc1cccc(C2CC(O)c3cc(O)ccc3O2)c1 -US05310740,2,O=C(OCc1ccccc1)C(Cc1ccccc1)CS(=O)(=O)Cl.O=C1CNCCN1>>O=C1CN(S(=O)(=O)CC(Cc2ccccc2)C(=O)OCc2ccccc2)CCN1 -US07037942B2,2,NC1Cc2ccccc2C1.O=C(Cl)c1ccc(F)cc1>>O=C(NC1Cc2ccccc2C1)c1ccc(F)cc1 -US07423159B2,7,CCOC(=O)c1cncn1-c1ccc(F)cc1>>OCc1cncn1-c1ccc(F)cc1 -US20080176870A1,1,COC(=O)c1cc(CBr)n2nccc2n1.Cc1c(C(=O)OC(C)(C)C)ccc2c1CCC2N>>COC(=O)c1cc(CNC2CCc3c2ccc(C(=O)OC(C)(C)C)c3C)n2nccc2n1 -US08785460B2,7,CCN(CC)C(=O)c1cccc2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl>>CCN(CC)Cc1cccc2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl -US06838463B2,1,CC#CCOc1ncnc(Cl)c1F.Oc1cccc(F)c1F>>CC#CCOc1ncnc(Oc2cccc(F)c2F)c1F -US20140288069A1,1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NCC(O)c1ccc(F)cc1>>OC(CNc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccc(F)cc1 -US20130310384A1,6,CC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)OC)c(F)c1F)S(=O)(=O)c1ccc(Cl)cc1>>CC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)O)c(F)c1F)S(=O)(=O)c1ccc(Cl)cc1 -US06632814B1,6,CCOC(=O)CCc1ccc2c(c1)NCCN2C(=O)Cc1ccc(NC(=O)Nc2ccccc2C)c(OC)c1>>COc1cc(CC(=O)N2CCNc3cc(CCC(=O)O)ccc32)ccc1NC(=O)Nc1ccccc1C -US20090181942A1,3,CCOc1c(OC)cccc1C(=O)c1cc(Cl)ccc1-n1cccc1.CN(C)C=O>>CCOc1c(OC)cccc1C(=O)c1cc(Cl)ccc1-n1ccc(C=O)c1 -US20100298377A1,7,Cc1nn(C(=O)OC(C)(C)C)c2ccc([N+](=O)[O-])cc12>>Cc1nn(C(=O)OC(C)(C)C)c2ccc(N)cc12 -US20150119373A1,4,C=C(C)[C@@H]1CC[C@]2(C(=O)N[C@@H]3C[C@H](C(=O)N4CCCCC4)C3(C)C)CC[C@]3(C)[C@H](CC[C@H]4[C@@]3(C)CC[C@H]3C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)O)CC[C@@]34C)[C@@H]12.O=C(OO)c1cccc(Cl)c1>>CC(C)(CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CO5)CC[C@]4(C(=O)N[C@@H]4C[C@H](C(=O)N5CCCCC5)C4(C)C)CC[C@]23C)C1(C)C)C(=O)O -US20100272680A1,2,CC(=O)Cl.Nc1cc(C(F)(F)F)c2nc(C(=O)N3CCC(N4CCOC4=O)CC3)c(Cl)n2c1>>CC(=O)Nc1cc(C(F)(F)F)c2nc(C(=O)N3CCC(N4CCOC4=O)CC3)c(Cl)n2c1 -US04401598,9,CCO[Si](CCCBr)(OCC)OCC.[N-]=[N+]=[N-]>>CCO[Si](CCCN=[N+]=[N-])(OCC)OCC -US03984459,2,CC(CCC(=O)O)CCC(=O)O.CCO>>CCOC(=O)CCC(C)CCC(=O)O -US06200974B1,6,CCOC(=O)C1C=Nc2c(cccc2[N+](=O)[O-])C1=O>>O=C(O)C1C=Nc2c(cccc2[N+](=O)[O-])C1=O -US20150111875A1,6,CC(C)(C)OC(=O)NC1CN(c2ccc3c(c2)[C@@H](Cc2ccccc2)[C@@H](N2CCC2)CC3)C1>>NC1CN(c2ccc3c(c2)[C@@H](Cc2ccccc2)[C@@H](N2CCC2)CC3)C1 -US08268822B2,3,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1.Clc1ccnc(Cl)n1>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1cccc(-c2ccnc(Cl)n2)c1 -US20110112299A1,1,CC/C(=C1\c2cc3cn[nH]c3cc2COc2ncccc21)c1cccc([N+](=O)[O-])c1.CCI>>CC/C(=C1\c2cc3cnn(CC)c3cc2COc2ncccc21)c1cccc([N+](=O)[O-])c1 -US06936602B1,1,CC(C)(C)OC(=O)CCCNC1CC1.O=Cc1cc(Br)ccc1F>>CC(C)(C)OC(=O)CCCN(c1ccc(Br)cc1C=O)C1CC1 -US05616546,2,CN(C)CCO.O=C(Cl)Oc1ccccc1>>CN(C)CCOC(=O)Oc1ccccc1 -US20070225292A1,6,CC(C)(C)OC(=O)Nc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCOCC2)c2ccccc12>>Nc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCOCC2)c2ccccc12 -US20130045986A1,3,CC(C)OC(=O)N1CCC(c2nc3ccc(B4OC(C)(C)C(C)(C)O4)cc3o2)CC1.NC(=O)c1ccc(Br)cc1F>>CC(C)OC(=O)N1CCC(c2nc3ccc(-c4ccc(C(N)=O)c(F)c4)cc3o2)CC1 -US04357351,2,CCCCCCCN=C(NCCCCCCC)SCC.O=C(Cl)Cl>>CCCCCCCN=C(SCC)N(CCCCCCC)C(=O)Cl -US07582626B2,2,CCOC(=O)C1CCCC1NCc1ccc(F)cc1.O=C(O)CC1=NS(=O)(=O)c2ccccc2N1>>CCOC(=O)C1CCCC1N(Cc1ccc(F)cc1)C(=O)CC1=NS(=O)(=O)c2ccccc2N1 -US04421758,1,Clc1ccc(OCC2CCC=CO2)c(Cl)c1.OC(CBr)c1ccc(Cl)cc1Cl>>Clc1ccc(OC[C@H]2CCC[C@H](OC(CBr)c3ccc(Cl)cc3Cl)O2)c(Cl)c1 -US20140121206A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOc1cc(C)c(N)cn1>>CCOc1cc(C)c(NC(=O)OC(C)(C)C)cn1 -US20040063170A1,9,CCc1ccc(Cc2ccc(C(=O)OC)cc2O)cc1.N>>CCc1ccc(Cc2ccc(C(N)=O)cc2O)cc1 -US09156827B2,6,COC(=O)c1ccc2c(/C=C3\Oc4c(ccc(O)c4CN4CCN(C(=O)OC(C)(C)C)CC4)C3=O)c[nH]c2c1>>COC(=O)c1ccc2c(/C=C3\Oc4c(ccc(O)c4CN4CCNCC4)C3=O)c[nH]c2c1 -US20120101083A1,6,CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCN(C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)O)CC4)no2)cc1C#N>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCN(C(=O)[C@@H](N)[C@@H](C)O)CC4)no2)cc1C#N -US20120022058A1,3,CCOC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)nc1OCC.Cc1nc(N2N=C(Cl)C[C@@H]2C2CCCC2)ccc1C#N>>CCOC(=O)c1ccc(C2=NN(c3ccc(C#N)c(C)n3)[C@@H](C3CCCC3)C2)nc1OCC -US04187216,2,CCCCCN.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CCCCCNC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 -US20130005751A1,1,Cc1cc2c(F)c(Oc3ccnc(CO)n3)ccc2n1C(=O)Nc1cccc(C(F)(F)F)c1.NCCO>>Cc1cc2c(F)c(Oc3ccnc(CNCCO)n3)ccc2n1C(=O)Nc1cccc(C(F)(F)F)c1 -US07649001B2,1,C1CCCNCC1.N#Cc1ccc(F)c2ccccc12>>N#Cc1ccc(N2CCCCCC2)c2ccccc12 -US20140148453A1,2,CC(=O)O.Cc1cc(N)ccc1Br>>CC(=O)Nc1ccc(Br)c(C)c1 -US05382590,2,CC(C)(C)OC(=O)CN(C(=O)CN(C(=O)CN)c1ccccc1)c1ccccc1.Cc1cccc(N=C=O)c1>>Cc1cccc(NC(=O)NCC(=O)N(CC(=O)N(CC(=O)OC(C)(C)C)c2ccccc2)c2ccccc2)c1 -US06753432B2,7,COC(=O)Cc1nc(-c2ccccc2)oc1C>>Cc1oc(-c2ccccc2)nc1CCO -US20040180874A1,2,CC(C)(C)OC(=O)N1CCN(c2cccc3c2CCNC3)CC1.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2cccc3c2CCN(S(=O)(=O)c2ccccc2)C3)CC1 -US04123613,2,CO[C@]12C[C@@H](CO)CN(C)[C@@H]1Cc1cn(C)c3cccc2c13.Cc1ccc(S(=O)(=O)Cl)cc1>>CO[C@]12C[C@@H](COS(=O)(=O)c3ccc(C)cc3)CN(C)[C@@H]1Cc1cn(C)c3cccc2c13 -US20080255239A1,6,COC(=O)C1Cc2ccc(F)cc2C1>>O=C(O)C1Cc2ccc(F)cc2C1 -US06586633B1,1,CC(=O)c1cccc(CBr)c1.CCN>>CCNCc1cccc(C(C)=O)c1 -US20060167023A1,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.N#Cc1ccc2c(c1)CNCC2>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2ccc(C#N)cc2C1 -US20050176775A1,6,CC(=O)OCC(=O)NCc1cnc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cn1>>Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1cnc(CNC(=O)CO)cn1 -US06747024B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc2c(c1)CCN2>>COC(=O)c1ccc2c(c1)CCN2C(=O)OC(C)(C)C -US20110237622A1,1,CC(C)(C)[Si](C)(C)OCCCO.Cc1cc(Cl)c(O)c(Cl)c1>>Cc1cc(Cl)c(OCCCO[Si](C)(C)C(C)(C)C)c(Cl)c1 -US08598168B2,3,Brc1ccc(N2CCOCC2)nc1.C=CC(=O)O>>O=C(O)/C=C/c1ccc(N2CCOCC2)nc1 -US07335687B2,3,BrCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.CN(C(=O)OCc1ccccc1)[C@@H]1CC[C@@H](C=O)CC1>>CN(C(=O)OCc1ccccc1)C1CCC(C=CCCCBr)CC1 -US20100048568A1,2,Nn1ccc2cc(F)ccc21.O=C(O)c1cnc(-c2ccccn2)nc1>>O=C(Nn1ccc2cc(F)ccc21)c1cnc(-c2ccccn2)nc1 -US07829732B2,1,CCO.O=Cc1ccc(CCl)o1>>CCOCc1ccc(C=O)o1 -US20150018363A1,1,Clc1ccc(CBr)cc1.O=c1cc(O)cnn1C1CCCCO1>>O=c1cc(OCc2ccc(Cl)cc2)cnn1C1CCCCO1 -US20140249132A1,6,CCOc1c(C2(C)OCCO2)cc(Cl)c(F)c1C1CNC(=O)C1>>CCOc1c(C(C)=O)cc(Cl)c(F)c1C1CNC(=O)C1 -US20110269741A1,3,CCOC(=O)c1cn([C@@H](C(C)C)C(C)(C)O[SiH2]C(C)(C)C)c2cc(Cl)cnc2c1=O.Fc1ccc(C[Zn+])cc1F>>CCOC(=O)c1cn([C@@H](C(C)C)C(C)(C)O[SiH2]C(C)(C)C)c2cc(Cc3ccc(F)c(F)c3)cnc2c1=O -US07157487B2,2,COC(=O)c1ccc(OC[C@@H]2C[C@H](Oc3ccc4ccccc4c3)CN2)cc1.Cc1ccccc1Nc1nc2ccc(CC(=O)O)cc2o1>>COC(=O)c1ccc(OC[C@@H]2C[C@H](Oc3ccc4ccccc4c3)CN2C(=O)Cc2ccc3nc(Nc4ccccc4C)oc3c2)cc1 -US20020052295A1,2,CC(N)CN.COC(=O)c1cccc(C(F)(F)F)c1>>CC(N)CNC(=O)c1cccc(C(F)(F)F)c1 -US08093239B2,1,COc1cc([N+](=O)[O-])c(OC)cc1Cl.FCCN1CCN(C2CCNCC2)CC1>>COc1cc([N+](=O)[O-])c(OC)cc1N1CCC(N2CCN(CCF)CC2)CC1 -US20120065184A1,1,CCOC(=O)c1cnc2ccc(Cl)nn12.Fc1cccc(C2CCCCN2)c1>>CCOC(=O)c1cnc2ccc(N3CCCCC3c3cccc(F)c3)nn12 -US20090227588A1,2,CNC.O=C(O)Cn1cc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)nc2)ccc1=O>>CN(C)C(=O)Cn1cc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)nc2)ccc1=O -US20130096084A1,6,CCOC(=O)c1ccc2c(c1)c(-c1ccnc(C)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc(C(=O)O)cc23)ccn1 -US04613618,7,COc1cc([N+](=O)[O-])ccc1S(=O)(=O)NCCCCCC(=O)O>>COc1cc(N)ccc1S(=O)(=O)NCCCCCC(=O)O -US20100179109A1,3,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)c2ccccc2Oc2cccc(F)c2)C1.COCCCC[Mg+]>>COCCCCC(O)(c1ccccc1Oc1cccc(F)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20020156081A1,6,Nc1ncnc2c1c(I)nn2C1CCC2(CC1)OCCO2>>Nc1ncnc2c1c(I)nn2C1CCC(=O)CC1 -US20140288126A1,2,Cn1c(-c2cncc(CN)c2)cc2ccccc21.O=S(=O)(Cl)C(F)(F)F>>Cn1c(-c2cncc(CNS(=O)(=O)C(F)(F)F)c2)cc2ccccc21 -US06765014B1,6,COC(=O)Cc1cc2c(c([N+](=O)[O-])c1)N(C(C)=O)CC2>>COC(=O)Cc1cc2c(c([N+](=O)[O-])c1)NCC2 -US05461157,1,Cc1cccc(C)c1NC(=O)CCl.O=C1CCCN1>>Cc1cccc(C)c1NC(=O)CN1CCCC1=O -US20050143422A1,1,BrCc1ccccc1.CCOC(=O)c1oc2ccc(CC)c(O)c2c1C>>CCOC(=O)c1oc2ccc(CC)c(OCc3ccccc3)c2c1C -US20100216746A1,2,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1.O=C(NC1CC1)c1cc(Cl)c(C(=O)O)[nH]1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]c(C(=O)NC4CC4)cc3Cl)c2F)c1 -US03952001,1,C=CCN(CC=C)C(=O)Cl.CC(C)CSc1nc[nH]n1>>C=CCN(CC=C)C(=O)n1cnc(SCC(C)C)n1 -US06974802B2,6,COc1ccc(COC(=O)C(C)OC(=O)[C@@H](NC(=O)OCc2ccccc2)C(C)C)cc1>>CC(OC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)O -US04723033,9,COc1ccc2cc([C@H](C)C(=O)O)ccc2c1Cl>>COc1ccc2cc([C@H](C)C(=O)O)ccc2c1 -US20090233965A1,1,CI.CN1CCC(OC(=O)C(C)(c2cccc(C#N)c2)C2CCCC2)CC1>>CC(C(=O)OC1CC[N+](C)(C)CC1)(c1cccc(C#N)c1)C1CCCC1 -US06699861B1,1,CC(=O)[O-].O=c1[nH]c(CCl)nc2cc3c(cc12)CCC3>>CC(=O)OCc1nc2cc3c(cc2c(=O)[nH]1)CCC3 -US20150252030A1,1,COC(=O)CBr.Cc1ccnc(C)c1O>>COC(=O)COc1c(C)ccnc1C -US20130102576A1,6,CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)N(CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC3CC3)c1)C2>>Nc1ccc2c(c1)C(=O)N(CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC3CC3)c1)C2 -US20100048623A1,8,OC(CCC(F)(F)F)CCC(F)(F)F>>O=C(CCC(F)(F)F)CCC(F)(F)F -US20100130492A1,2,CC(C)Cn1c(N2CCN[C@@H](C)C2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21.C[C@@H](O)CC(=O)O>>CC(C)Cn1c(N2CCN(C(=O)C[C@@H](C)O)[C@@H](C)C2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21 -US04634713,1,ClCC1CC1.Oc1ccccc1O>>Oc1ccccc1OCC1CC1 -US20080194549A1,6,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C(=O)NCc2ccccc2)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2C(=O)NCc2ccccc2)C(C)C)ccc1OC -US20090312338A1,6,Cc1ccc(S(=O)(=O)n2ccc3nc(N(N)C(=O)OC(C)(C)C)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3nc(NN)cnc32)cc1 -US07179912B2,2,CN.COc1ccc(S(=O)(=O)Cl)c(N2CCOCC2)c1>>CNS(=O)(=O)c1ccc(OC)cc1N1CCOCC1 -US20110275762A1,1,Clc1nc(Cl)nc(Cl)n1.NCc1ccccn1>>Clc1nc(Cl)nc(NCc2ccccn2)n1 -US20050250792A1,2,COC(=O)CCC(=O)Cl.NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>COC(=O)CCC(=O)NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 -US20140206662A1,1,Cc1ccc2nc(-c3ccc(I)cc3)c(CO)n2c1.NCCN>>Cc1ccc2nc(-c3ccc(NCCN)cc3)c(CO)n2c1 -US05624950,2,COc1ccccc1C1(O)C(C)CCC2CNCC21.O=C(O)Cc1c[nH]c2ccccc12>>COc1ccccc1C1(O)C(C)CCC2CN(C(=O)Cc3c[nH]c4ccccc34)CC21 -US07745484B2,7,O=C(c1ccc(O)cc1)C(F)(F)F>>Oc1ccc(C(O)C(F)(F)F)cc1 -US20030225266A1,3,CC(CNS(=O)(=O)C(C)C)Oc1ccc(Br)cc1.OB(O)c1ccccc1F>>CC(CNS(=O)(=O)C(C)C)Oc1ccc(-c2ccccc2F)cc1 -US07704994B2,2,O=C(Cl)C1CCCC1.c1cc2c(cc1OC1CCNCC1)CCN(C1CCC1)CC2>>O=C(C1CCCC1)N1CCC(Oc2ccc3c(c2)CCN(C2CCC2)CC3)CC1 -US20110319379A1,2,CCn1cc2c(Oc3ccc(S(C)(=O)=O)cc3)cc(C(=O)OC)cc2n1.Cn1ncc(N)n1>>CCn1cc2c(Oc3ccc(S(C)(=O)=O)cc3)cc(C(=O)Nc3cnn(C)n3)cc2n1 -US20070072920A1,1,COc1cc(C[C@@H](C)NC(=O)C(F)(F)F)c(OC)cc1CCCBr.C[S-]>>COc1cc(C[C@@H](C)NC(=O)C(F)(F)F)c(OC)cc1CCCSC -US20150005300A1,1,BrCc1ccccn1.CCN(C(=O)Cn1ncc2[nH]c3ccccc3c2c1=O)c1ccc2c(c1)OC(F)(F)O2>>CCN(C(=O)Cn1ncc2c(c1=O)c1ccccc1n2Cc1ccccn1)c1ccc2c(c1)OC(F)(F)O2 -US20080255192A1,3,O=C1Nc2c(I)cccc2C1=O.OB(O)c1ccccc1>>O=C1Nc2c(cccc2-c2ccccc2)C1=O -US05534510,2,O=C(O)[C@@H]1CCCN1.O=[N+]([O-])c1ccc(CO)cc1>>O=C(OCc1ccc([N+](=O)[O-])cc1)[C@@H]1CCCN1 -US20110105535A1,8,CCc1cnc(CCNC(=O)Nc2nc(C)c(-c3cc(C)nc(SC)n3)s2)o1.O=C(OO)c1cccc(Cl)c1>>CCc1cnc(CCNC(=O)Nc2nc(C)c(-c3cc(C)nc(S(C)=O)n3)s2)o1 -US05104888,1,CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2.CC(C)(C)OC(=O)CBr>>CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(COc1ccc(CC3SC(=O)N(CC(=O)OC(C)(C)C)C3=O)cc1)O2 -US08557805B2,2,CCN.CS(=O)(=O)c1ccc(Oc2ccc3[nH]c(C4=NCC(CC(=O)O)S4)cc3c2)cn1>>CCNC(=O)CC1CN=C(c2cc3cc(Oc4ccc(S(C)(=O)=O)nc4)ccc3[nH]2)S1 -US04663319,3,CCOC(=O)CC(=O)N(CCC(=O)OC)Cc1ccc(NC(=O)OCc2ccccc2)cc1>>CCOC(=O)C1C(=O)CCN(Cc2ccc(NC(=O)OCc3ccccc3)cc2)C1=O -US05849735,2,O=C(Cl)c1ccc(C(=O)c2ccccc2)cc1.c1ccc2c(c1)CCc1ccccc1NC2>>O=C(c1ccccc1)c1ccc(C(=O)N2Cc3ccccc3CCc3ccccc32)cc1 -US07105567B2,2,CC(C)c1cccc(C(C)C)c1N=C=O.Cc1ccc(CNc2ccc(C(C)C)cc2)c(C)c1>>Cc1ccc(CN(C(=O)Nc2c(C(C)C)cccc2C(C)C)c2ccc(C(C)C)cc2)c(C)c1 -US20140228377A1,2,CC1CCC(C(=O)O)CN1C(=O)OC(C)(C)C.Nc1cc(Cl)ccc1O>>CC1CCC(C(=O)Nc2cc(Cl)ccc2O)CN1C(=O)OC(C)(C)C -US06159904,2,CCOC(=O)c1ccc2c(c1C)C(O)C(C)(C)CS2(=O)=O.CS(=O)(=O)Cl>>CCOC(=O)c1ccc2c(c1C)C(OS(C)(=O)=O)C(C)(C)CS2(=O)=O -US20050187266A1,1,CCI.CCOC(=O)C1(C(O)c2ccc(OCCc3nc(-c4ccccc4)oc3C)nc2)CCC1>>CCOC(=O)C1(C(OCC)c2ccc(OCCc3nc(-c4ccccc4)oc3C)nc2)CCC1 -US04496566,1,C=O.O=C(O)c1cn(CCF)c2nc(N3CCNCC3)c(F)cc2c1=O>>CN1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3CCF)CC1 -US04997835,9,Clc1cccc(Cl)n1.NN>>NNc1cccc(Cl)n1 -US20090253726A1,6,COc1c(N2CC3(CC3)C(C)(NC(=O)OC(C)(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12>>COc1c(N2CC(C)(N)C3(CC3)C2)c(F)cc2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12 -US20070293558A1,1,CC(C)(C)CCBr.COc1ccc2c(c1)[nH]c1ccccc12>>COc1ccc2c3ccccc3n(CCC(C)(C)C)c2c1 -US07767691B2,1,OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2.Oc1ccccc1OCCCBr>>Oc1ccccc1OCCC[N+]12CCC(C(O)(c3ccccc3)c3ccccc3)(CC1)C2 -US20070149521A1,6,CCOC(=O)CSc1nc(-c2cc3ccccc3[nH]2)c2c(N)nccn12>>Nc1nccn2c(SCC(=O)O)nc(-c3cc4ccccc4[nH]3)c12 -US07528136B2,1,CNC1CC(C(=O)N2CCN(c3ccccc3C#N)CC2)N(Cc2ccccc2)C1.O=Cc1ccc(Cl)c(Cl)c1>>CN(Cc1ccc(Cl)c(Cl)c1)C1CC(C(=O)N2CCN(c3ccccc3C#N)CC2)N(Cc2ccccc2)C1 -US05968924,1,CC(C)(C)OC(=O)NCc1ccccc1-c1ccc(CO)cc1.CC(C)(NC(=O)OCc1ccccc1)C(=O)N[C@@H]1CCc2ccccc2NC1=O>>CC(C)(C)OC(=O)NCc1ccccc1-c1ccc(CN2C(=O)[C@H](NC(=O)C(C)(C)NC(=O)OCc3ccccc3)CCc3ccccc32)cc1 -US08680091B2,6,CC(C)(C)OC(=O)NCc1ccc(NC(=O)C(C)(C)C)cc1>>CC(C)(C)C(=O)Nc1ccc(CN)cc1 -US20060160794A1,2,CNCc1ccccc1Cl.O=C(O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1Cl>>CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1Cl -US04489087,1,CCCCCCCCC(=O)CCCBr.c1c[nH]cn1>>CCCCCCCCC(=O)CCCn1ccnc1 -US20120270865A2,2,CCOC(=O)CCNC.COc1ccc2oc(C(Nc3ccc(C(=O)O)cc3)C3CCCCC3)c(Br)c2c1>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(OC)cc3c2Br)C2CCCCC2)cc1 -US20100184815A1,2,Cc1ccc(CN(N)C(N)=O)cc1.O=C(Cl)COCc1ccccc1>>Cc1ccc(CN(NC(=O)COCc2ccccc2)C(N)=O)cc1 -US20050239832A1,9,CCc1ccc2c(c1)C(=O)CCN2C.NO>>CCc1ccc2c(c1)/C(=N/O)CCN2C -US20110015157A1,4,CC(=O)O.C[C@@H](c1ccc(-c2ccc(N)c(N)c2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>Cc1nc2ccc(-c3ccc([C@H](C)N4CC[C@](CC(C)(C)O)(c5ccccc5)OC4=O)cc3)cc2[nH]1 -US20150011548A1,6,CC(=O)Nc1cc(-c2c(F)cccc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1>>Nc1cc(-c2c(F)cccc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 -US07858626B2,1,C=O.Cc1n[nH]c2cc(N)ccc12>>CNc1ccc2c(C)n[nH]c2c1 -US20100324010A1,9,CC(C)CN(C(=O)c1cnc(C(C)(C)C)nc1NCc1ccco1)[C@H]1C[C@@H](C(N)=O)CN(C(=O)OC(C)(C)C)C1>>CC(C)CN(C(=O)c1cnc(C(C)(C)C)nc1NCc1ccco1)[C@H]1C[C@@H](C#N)CN(C(=O)OC(C)(C)C)C1 -US07094789B2,2,CC(C)(C)OC(=O)NCc1cccc(CN)c1.O=S(=O)(Cl)c1cccc2cnccc12>>CC(C)(C)OC(=O)NCc1cccc(CNS(=O)(=O)c2cccc3cnccc23)c1 -US20060079520A1,1,Cc1c[nH]c2c(Br)cc(F)cc12.Oc1ccc(Cl)cc1Cl>>Cc1c[nH]c2c(Oc3ccc(Cl)cc3Cl)cc(F)cc12 -US20120264735A1,3,Cc1cnc(Br)[nH]1.Cn1cc(-n2ccc(=O)c(Cc3cccc(B4OC(C)(C)C(C)(C)O4)c3)n2)cn1>>Cc1cnc(-c2cccc(Cc3nn(-c4cnn(C)c4)ccc3=O)c2)[nH]1 -US20120208827A1,2,CN1CCNCC1.O=C(O)c1ccc2nc(-c3ccc(Br)cc3)n(C[C@@H]3CCN(C(=O)C4CC4)C3)c2c1>>CN1CCN(C(=O)c2ccc3nc(-c4ccc(Br)cc4)n(C[C@@H]4CCN(C(=O)C5CC5)C4)c3c2)CC1 -US09090599B2,2,NCc1nc(C(F)(F)F)no1.O=C(O)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2F)c1>>O=C(NCc1nc(C(F)(F)F)no1)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2F)c1 -US20110275622A1,8,COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5ccc(-c6ccc(CO)cc6)cc5)c4)cc23)c1>>COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5ccc(-c6ccc(C=O)cc6)cc5)c4)cc23)c1 -US06716841B2,7,N#Cc1cccc(-n2nc(C(F)(F)F)cc2C(=O)N2CCc3cc(-c4ccccc4S(N)(=O)=O)ccc32)c1>>NCc1cccc(-n2nc(C(F)(F)F)cc2C(=O)N2CCc3cc(-c4ccccc4S(N)(=O)=O)ccc32)c1 -US20040254236A1,2,CCOC(=O)CC(=O)c1ccccc1.NCC1CC1>>O=C(CC(=O)c1ccccc1)NCC1CC1 -US04451551,2,CN(C)CCO.[N-]=[N+]=Nc1ccc(C=CC(=O)O)cc1>>CN(C)CCOC(=O)C=Cc1ccc(N=[N+]=[N-])cc1 -US06197769B1,1,CC(C)Br.CC(C)COC(=O)c1n[nH]c2ccccc12>>CC(C)COC(=O)c1nn(C(C)C)c2ccccc12 -US04384123,9,[N-]=[N+]=NC1C[C@@H](C(=O)O)N(C(=O)CP(=O)(O)CCCCc2ccccc2)C1>>NC1C[C@@H](C(=O)O)N(C(=O)CP(=O)(O)CCCCc2ccccc2)C1 -US06498172B1,2,COC(=O)CCc1cccc(CNCc2ccc(-c3ncccn3)cc2)c1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)CCc1cccc(CN(Cc2ccc(-c3ncccn3)cc2)S(=O)(=O)c2ccc(Cl)cc2)c1 -US20130289020A1,2,CCC(NC(=O)OC(C)(C)C)C(=O)O.CNOC>>CCC(NC(=O)OC(C)(C)C)C(=O)N(C)OC -US06313132B1,6,COc1ccccc1C(CC(=O)N(C(C)C)C(C)C)c1cccs1>>CC(C)N(C(=O)CC(c1cccs1)c1ccccc1O)C(C)C -US05726325,2,C[C@](O)(C(=O)O)C(F)(F)F.Nc1cccc2c1C(=O)c1sccc1CO2>>C[C@](O)(C(=O)Nc1cccc2c1C(=O)c1sccc1CO2)C(F)(F)F -US05925661,6,CC(=O)Nc1ccc(C#N)cc1C1CC1>>N#Cc1ccc(N)c(C2CC2)c1 -US20040162287A1,1,CN(C)C1(c2ccccc2)CCC(=O)CC1.NCCc1c[nH]c2ccccc12>>CN(C)C1(c2ccccc2)CCC(NCCc2c[nH]c3ccccc23)CC1 -US04311699,2,CC(=O)OC(C)=O.CC(C)(N)C(=O)O>>CC(=O)NC(C)(C)C(=O)O -US20100273771A1,1,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)OCCNC4)no2)cc1Cl.CCOC(=O)CCCBr>>CCOC(=O)CCCN1CCOc2cc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)ccc2C1 -US20080015256A1,7,N#CCCC1CCCc2cc(S(=O)(=O)c3ccccc3)ccc21>>NCCCC1CCCc2cc(S(=O)(=O)c3ccccc3)ccc21 -US05212173,1,CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OCCN(C)CCCl.NCCCCc1ccccc1>>CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OCCN(C)CCNCCCCc1ccccc1 -US20100256112A1,1,CC(C)(N)[C@@H]1CCNC1.COc1c(F)c(F)cc2c(=O)c3c(O)c(C(N)=O)sc3n(C3CC3)c12>>COc1c(N2CC[C@@H](C(C)(C)N)C2)c(F)cc2c(=O)c3c(O)c(C(N)=O)sc3n(C3CC3)c12 -US04587261,1,CCOc1c(OC)cc(C(=O)NN)cc1OC.O=C1CCCC1=Cc1ccccc1>>CCOc1c(OC)cc(C(=O)NN=C2CCCC2=Cc2ccccc2)cc1OC -US20070185079A1,1,COc1ccc2nc(N[C@H]3CC[C@H](N)C3)cc(C)c2c1.Cn1cc(Cl)c(C=O)n1>>COc1ccc2nc(N[C@H]3CC[C@H](NCc4nn(C)cc4Cl)C3)cc(C)c2c1 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2cccc(C(F)(F)F)c2)cc1.O=C(O)c1ccc(F)c2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2cccc(C(F)(F)F)c2)C(=O)c2ccc(F)c3cc[nH]c23)cc1 -US20130190312A1,4,Cc1cc(OCC2CC2)cc(C)c1C(=O)CBr.NC(N)=S>>Cc1cc(OCC2CC2)cc(C)c1-c1csc(N)n1 -US08552205B2,2,CC(C)(C)OC(=O)C1(N)CC1.C[C@@]1(Cc2ccc(C#N)cc2)C(=O)N(c2cc(Cl)cc(Cl)c2)c2ncc(C(=O)O)n21>>CC(C)(C)OC(=O)C1(NC(=O)c2cnc3n2[C@](C)(Cc2ccc(C#N)cc2)C(=O)N3c2cc(Cl)cc(Cl)c2)CC1 -US08067408B2,6,N#Cc1cc(Br)cc(CN2C(=O)c3ccccc3C2=O)c1>>N#Cc1cc(Br)cc(CN)c1 -US05321036,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C[C@@H](C)N>>COC(=O)C[C@@H](C)NC(=O)OC(C)(C)C -US04411913,1,CC(C)(C)N.CC1(C)CCc2c(cccc2OCC(O)CCl)CC1=O>>CC(C)(C)NCC(O)COc1cccc2c1CCC(C)(C)C(=O)C2 -US20130324516A1,3,Nc1ncnc2ccc(Cl)nc12.O=C(O)c1cccc(B(O)O)c1>>Nc1ncnc2ccc(-c3cccc(C(=O)O)c3)nc12 -US04859692,6,COC(=O)c1ccc(Cc2cn(C)c3ccc(NC(=O)OC4CCCC4)cc23)c(OC)c1>>COc1cc(C(=O)O)ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12 -US20090181963A1,3,COC(=O)c1ccc(Cn2nnc3c(N4CCOCC4)nc(Cl)nc32)cc1.OCc1cccc(B(O)O)c1>>COC(=O)c1ccc(Cn2nnc3c(N4CCOCC4)nc(-c4cccc(CO)c4)nc32)cc1 -US20080045530A1,2,C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1.CC(C)(C)OC(=O)N1CC[C@H](C(=O)O)C1>>C=C[C@@H]1C[C@]1(NC(=O)[C@H]1CCN(C(=O)OC(C)(C)C)C1)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1 -US08183262B2,3,Cc1cc(-c2ccc(Cl)cc2)cc(I)n1.OB(O)c1cccc(Br)c1>>Cc1cc(-c2ccc(Cl)cc2)cc(-c2cccc(Br)c2)n1 -US20150218169A1,6,CCOC(=O)C1(C)CCN(c2nn(C(=O)c3c(Cl)cccc3C3CC3)c3cccc(F)c23)CC1O>>CC1(C(=O)O)CCN(c2nn(C(=O)c3c(Cl)cccc3C3CC3)c3cccc(F)c23)CC1O -US20070299057A9,1,Fc1ccc(CC2CCNCC2)cc1.O=CC1CCN(C(=O)OCc2ccccc2)C1>>O=C(OCc1ccccc1)N1CCC(CN2CCC(Cc3ccc(F)cc3)CC2)C1 -US07951806B2,2,CC(C)(C)OC(=O)c1c(-c2ccccc2)csc1NC(=O)CCCCC(=O)O.c1ccc(C2CCNCC2)cc1>>CC(C)(C)OC(=O)c1c(-c2ccccc2)csc1NC(=O)CCCCC(=O)N1CCC(c2ccccc2)CC1 -US20080188506A1,7,O=C1CC(c2cccc(Cl)c2)C2(C(=O)Nc3cc(Cl)ccc32)C(c2cccc(F)c2)N1>>O=C1Nc2cc(Cl)ccc2C12C(c1cccc(Cl)c1)CCNC2c1cccc(F)c1 -US20150038488A1,3,CC(C)(O)c1ncc(Br)s1.C[C@@H](Oc1cc(B2OC(C)(C)C(C)(C)O2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1>>C[C@@H](Oc1cc(-c2cnc(C(C)(C)O)s2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1 -US04788195,6,CCOC(=O)c1ccc(Nc2nccc(-c3cccnc3)n2)cc1>>O=C(O)c1ccc(Nc2nccc(-c3cccnc3)n2)cc1 -US06403594B1,7,COc1ccc(C#N)cc1[N+](=O)[O-]>>COc1ccc(C#N)cc1N -US20100311748A1,6,COC(=O)c1ccc(OCc2ncccc2N2CCN(C)CC2)cc1>>CN1CCN(c2cccnc2COc2ccc(C(=O)O)cc2)CC1 -US08796256B2,1,C=O.O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1C[C@@H]1CNCCO1>>CN1CCO[C@H](CN2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)C1 -US20120052130A1,6,COC(=O)c1ccc2c(n1)CCN2c1cc(O[C@H]2CCN(C(=O)OC3(C)CC3)C[C@H]2F)ncn1>>CC1(OC(=O)N2CC[C@H](Oc3cc(N4CCc5nc(C(=O)O)ccc54)ncn3)[C@H](F)C2)CC1 -US20060058358A1,2,CNC(=O)c1cc(Oc2ccc(N)c(F)c2)ccn1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)ccn1 -US05541229,2,CC(=O)Cl.CCCCc1nc2c(C)ccc(O)c2n1Cc1ccc(-c2ccccc2C(=O)O)cc1>>CCCCc1nc2c(C)ccc(OC(C)=O)c2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20090093459A1,7,CC(C)(C)C(=O)ON[C@@H](CSc1cccc(F)c1[N+](=O)[O-])C(=O)O>>CC(C)(C)C(=O)ON[C@@H](CSc1cccc(F)c1N)C(=O)O -US20150038523A1,2,CCOC(=O)c1csc(N)n1.O=C=NCc1ccccc1>>CCOC(=O)c1csc(NC(=O)NCc2ccccc2)n1 -US07259183B2,1,CC(C)(C)c1ccc(C=O)cc1.NCCc1ccc(Cl)c(C(F)(F)F)c1>>CC(C)(C)c1ccc(CNCCc2ccc(Cl)c(C(F)(F)F)c2)cc1 -US05801183,2,CCOC(=O)c1cc(Cl)cnc1N.O=C(Cl)Cc1cccc(Oc2ccccc2)c1>>CCOC(=O)c1cc(Cl)cnc1NC(=O)Cc1cccc(Oc2ccccc2)c1 -US20110105754A1,6,CCCCCCCCN(C(C)=O)c1ccccc1>>CCCCCCCCNc1ccccc1 -US08293747B2,1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1cnccc1Cl>>CC(C)(C)OC(=O)N1CCN(c2ccncc2[N+](=O)[O-])CC1 -US20070037821A1,2,CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)OC(C)(C)C.O=[N+]([O-])OCCCO>>CC(C)(C)OC(=O)N[C@@H](CCC(=O)OCCCO[N+](=O)[O-])C(=O)OC(C)(C)C -US05594004,9,O=C(CCl)c1ccc(O)c(O)c1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(=O)c1ccc(O)c(O)c1 -US20040097503A1,1,Cc1cc2c(ncn2C)c(N)c1C.FC(F)(F)c1cc(Cl)nc(-c2cccnc2)n1>>Cc1cc2c(ncn2C)c(Nc2cc(C(F)(F)F)nc(-c3cccnc3)n2)c1C -US20140288123A1,6,COC(=O)c1ccc(C(C)Oc2ccccn2)cc1>>CC(Oc1ccccn1)c1ccc(C(=O)O)cc1 -US07335673B2,6,CCOC(=O)C(Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)c1ccc(OC)c(N(CC(C)C)C(=O)C(C)(C)C)c1>>COc1ccc(C(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)cc1N(CC(C)C)C(=O)C(C)(C)C -US20100099665A1,1,CC(C)(C)OC(=O)N1CCN(Cc2c[nH]c(=O)c3ccc(Br)cc23)CC1.CC(C)(C)[Si](C)(C)OCC1(COS(C)(=O)=O)CCC1>>CC(C)(C)OC(=O)N1CCN(Cc2cn(CC3(CO[Si](C)(C)C(C)(C)C)CCC3)c(=O)c3ccc(Br)cc23)CC1 -US08101637B2,3,Brc1ccccn1.C#CCCn1nc2cccc(Cl)c2n1>>Clc1cccc2nn(CCC#Cc3ccccn3)nc12 -US20070281946A1,2,COC(=O)c1ccc(C(CC2CCOCC2)C(=O)O)cc1.Nc1nccs1>>COC(=O)c1ccc(C(CC2CCOCC2)C(=O)Nc2nccs2)cc1 -US20050159411A1,1,COc1ccc2nccc([C@@H](O)CN3CCC(N)CC3=O)c2c1.O=Cc1ccc2c(c1)NC(=O)CS2>>COc1ccc2nccc([C@@H](O)CN3CCC(NCc4ccc5c(c4)NC(=O)CS5)CC3=O)c2c1 -US20090192145A1,7,COc1ccc2c(c1)CCC2(N)C(=O)O>>COc1ccc2c(c1)CCC2(N)CO -US05506227,7,CCC=Cc1cccc(C)n1>>CCCCc1cccc(C)n1 -US20100298290A1,4,CC(C)(C)OC(=O)N1CCOc2ccc(-c3ccc(N)c(N)c3)cc2C1.CCN=C=S>>CCNc1nc2ccc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)CCO4)cc2[nH]1 -US20040133008A1,6,Cc1ccc(C(=O)Nc2ccc(OCCc3cccc(NC(=O)OC(C)(C)C)n3)cc2)c(OC(C)C)c1>>Cc1ccc(C(=O)Nc2ccc(OCCc3cccc(N)n3)cc2)c(OC(C)C)c1 -US20070027093A1,9,Clc1nnc(N2CCOCC2)cc1-c1ccccc1>>c1ccc(-c2cnnc(N3CCOCC3)c2)cc1 -US20120142667A1,1,COc1ccc(Nc2nc(Cl)ncc2Br)c(NS(C)(=O)=O)c1.COc1ccc(OC)c(N)c1>>COc1ccc(Nc2nc(Nc3cc(OC)ccc3OC)ncc2Br)c(NS(C)(=O)=O)c1 -US04013664,7,COc1cc2c(cc1O)C(Cc1c(OC)cccc1[N+](=O)[O-])N(C)CC2>>COc1cc2c(cc1O)C(Cc1c(N)cccc1OC)N(C)CC2 -US05942511,1,CCO.Cc1c(Cl)nnc(Cl)c1C>>CCOc1nnc(Cl)c(C)c1C -US08263610B2,6,COc1ccc(Cn2ncc3c4c(cnc32)CN(C(=O)OC(C)(C)C)CC4)cc1>>COc1ccc(Cn2ncc3c4c(cnc32)CNCC4)cc1 -US08299023B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)c1cc(N2CCCNCC2)ccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCCN(c2ccc([N+](=O)[O-])c(C(=O)O)c2)CC1 -US05449682,7,C=CCc1cc(C(=O)OC)ccc1O[Si](C)(C)C(C)(C)C>>C=CCc1cc(CO)ccc1O[Si](C)(C)C(C)(C)C -US06251912B1,1,CNC.O=C(C=CCBr)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1>>CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 -US04838931,2,Cc1cc(N=C=O)ccc1OC(F)(F)C(F)F.OCC1CCCCN1>>Cc1cc(NC(=O)N2CCCCC2CO)ccc1OC(F)(F)C(F)F -US20130116234A1,6,CCOC(=O)c1c(N2CCOCC2)nc2ccc(Cl)cc2c1-c1ccccc1>>O=C(O)c1c(N2CCOCC2)nc2ccc(Cl)cc2c1-c1ccccc1 -US20100029653A1,1,Fc1ccccc1Cc1n[nH]c2ncccc12.Nc1nc(N)nc(Cl)n1>>Nc1nc(N)nc(-n2nc(Cc3ccccc3F)c3cccnc32)n1 -US09102591B2,2,NCC(c1ccc(Cl)cc1)C1CCOCC1.O=C(O)c1c(F)cccc1Cl>>O=C(NCC(c1ccc(Cl)cc1)C1CCOCC1)c1c(F)cccc1Cl -US20030220355A1,3,C#CCN1CCOCC1.CC(C)(C)OC(=O)c1ccc(Cn2cnc3ccc(I)cc3c2=O)cc1>>CC(C)(C)OC(=O)c1ccc(Cn2cnc3ccc(C#CCN4CCOCC4)cc3c2=O)cc1 -US06051712,4,CC(C)(C)OC(=O)N1CCC(c2ccc(CCC(=O)NNC(=O)c3ccccc3)cc2)C(OCc2ccc3ccccc3c2)C1>>CC(C)(C)OC(=O)N1CCC(c2ccc(CCc3nnc(-c4ccccc4)o3)cc2)C(OCc2ccc3ccccc3c2)C1 -US05008245,2,NCCCC[C@H](N)C(=O)O.O=C(Cl)c1ccccc1>>N[C@@H](CCCCNC(=O)c1ccccc1)C(=O)O -US20090111808A1,1,ClCCCBr.Oc1ccc(-c2ccc(Br)cc2)cc1>>ClCCCOc1ccc(-c2ccc(Br)cc2)cc1 -US04777172,6,COCc1nccc(N2CCCCC2)n1>>OCc1nccc(N2CCCCC2)n1 -US08377895B2,3,C1CCNCC1.C=O.COc1c(O)cc(O)c2c(=O)cc(-c3ccccc3)oc12>>COc1c(O)c(CN2CCCCC2)c(O)c2c(=O)cc(-c3ccccc3)oc12 -US20120149691A1,1,N#Cc1cnn2cccc2c1Cl.NC1CCCCC1>>N#Cc1cnn2cccc2c1NC1CCCCC1 -US20120046300A1,6,CC(C)(C)OC(=O)N1CC2OCOC2C1>>C1OC2CNCC2O1 -US04680388,6,CC(C)(C)OC(=O)NC1C(=O)N(OS(=O)(=O)O)C12CCC2>>NC1C(=O)N(OS(=O)(=O)O)C12CCC2 -US20130345192A1,1,CN[C@H]1CCCN(Cc2ccccc2)C1.O=C1CCc2c(Cl)ncnc2N1>>CN(c1ncnc2c1CCC(=O)N2)[C@H]1CCCN(Cc2ccccc2)C1 -US20090186886A1,6,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])OCC2>>Nc1cc2c(cc1[N+](=O)[O-])OCC2 -US04968679,6,CCCN(CCC)C1CCc2cccc(CNC(C)=O)c2C1>>CCCN(CCC)C1CCc2cccc(CN)c2C1 -US05364871,2,CC(=O)NCc1cccc(-c2csc(N)n2)n1.CN=C=S>>CNC(=S)Nc1nc(-c2cccc(CNC(C)=O)n2)cs1 -US08268822B2,1,CCN(Cc1cccnc1)Cc1cccc(-c2ccnc(Cl)n2)c1.NCCc1ccc(O)cc1>>CCN(Cc1cccnc1)Cc1cccc(-c2ccnc(NCCc3ccc(O)cc3)n2)c1 -US07642256B2,2,CNCc1ccccc1.O=C(O)Cc1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1>>CN(Cc1ccccc1)C(=O)Cc1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1 -US06326386B1,2,CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)O)c1)c1ccncc1.CC(C)NCCS(=O)(=O)NCC(C)(C)C>>CC(C)N(CCS(=O)(=O)NCC(C)(C)C)C(=O)c1cc(Cl)cc(OCCN(C(=O)OC(C)(C)C)c2ccncc2)c1 -US05242914,6,CNC(=O)[C@@H]1C[C@H](SCc2ccc(OC)cc2)CN1C(=O)OC(C)(C)C>>CNC(=O)[C@@H]1C[C@H](SCc2ccc(OC)cc2)CN1 -US20100216799A1,9,COC(=O)c1ccncc1C(=O)C(C(=O)OC(C)(C)C)c1ccc(Cl)cc1>>COC(=O)c1ccncc1C(=O)Cc1ccc(Cl)cc1 -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.O=C=NCc1ccccc1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NCc3ccccc3)CC2)nc1C(F)(F)F -US08492378B2,1,COc1ccc(CCl)cc1C#N.O=C(CCc1ccccc1)Nc1cc(-c2nnc(S)o2)ccn1>>COc1ccc(CSc2nnc(-c3ccnc(NC(=O)CCc4ccccc4)c3)o2)cc1C#N -US20040142850A1,2,CCOC(=O)Cl.Nc1ccc(Cl)cc1Cl>>CCOC(=O)Nc1ccc(Cl)cc1Cl -US20100048581A1,2,CC(C)(C)OC(=O)NCc1ccc(Nc2ncc(Sc3ccnc(C(=O)O)c3F)s2)nc1.CCCC(O)(CN)c1ccccc1>>CCCC(O)(CNC(=O)c1nccc(Sc2cnc(Nc3ccc(CNC(=O)OC(C)(C)C)cn3)s2)c1F)c1ccccc1 -US06316487B1,1,CCC(C)OC(=O)CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1.CCN(CC)CCCl>>CCC(C)OC(=O)CCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1 -US20050245563A1,7,Cc1[nH]nc2c1c(=O)n(CCCN)c1ccc(C#CCO)cc21>>Cc1[nH]nc2c1c(=O)n(CCCN)c1ccc(CCCO)cc21 -US08367708B2,1,OB(O)c1ccc(F)nc1.OCCc1cccc(O)c1>>OCCc1cccc(Oc2ccc(F)nc2)c1 -US08609848B2,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)c2c1OC(C)(C)C2.O=S(=O)(Cl)c1ccc2ccccc2c1>>COc1ccc(C2=NN(C3CCN(S(=O)(=O)c4ccc5ccccc5c4)CC3)C(=O)C2(C)C)c2c1OC(C)(C)C2 -US06399774B1,2,Cc1cc(Br)ccc1C(=O)O.NC1CC1>>Cc1cc(Br)ccc1C(=O)NC1CC1 -US04259354,1,CBr.CCCCCCCCN(C)CCCCCCCC>>CCCCCCCC[N+](C)(C)CCCCCCCC -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nnn(C)n4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nnn(C)n4)cc2)CCN3CC(C)C)cc1 -US07705038B2,1,CC(C)=CCBr.N#C/C(=C\c1ccc[nH]1)c1ccc(Cl)cc1>>CC(C)=CCn1cccc1/C=C(\C#N)c1ccc(Cl)cc1 -US20110190276A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1CNC(=O)OCc1ccccc1>>O=C(NC[C@H]1CCCN1)OCc1ccccc1 -US08399681B2,3,CC(C)(C)OC(=O)N1CCN(C2=NC(=O)CS2)C[C@@H]1CO.O=Cc1ccc2c(c1)c(Cl)nn2Cc1ccc(C(F)(F)F)cc1C(F)(F)F>>CC(C)(C)OC(=O)N1CCN(C2=NC(=O)C(=Cc3ccc4c(c3)c(Cl)nn4Cc3ccc(C(F)(F)F)cc3C(F)(F)F)S2)C[C@@H]1CO -US20100261719A1,3,C#Cc1ccccn1.C[C@@H]1O[C@H](C)CN2c3ccc(I)cc3CC3(C(=O)NC(=O)NC3=O)[C@@H]12>>C[C@@H]1O[C@H](C)CN2c3ccc(C#Cc4ccccn4)cc3CC3(C(=O)NC(=O)NC3=O)C12 -US08524917B2,2,CC(C)(O)CN.CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C(=O)O)cc2n1Cc1ccccc1>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C(=O)NCC(C)(C)O)cc2n1Cc1ccccc1 -US04925859,2,CCOC(=O)c1cnc(-c2ccccc2)c(-c2ccccc2)c1O.Nc1nccs1>>O=C(Nc1nccs1)c1cnc(-c2ccccc2)c(-c2ccccc2)c1O -US07727997B2,7,COC(=O)c1cc(Br)cc(C(=O)O)c1>>O=C(O)c1cc(Br)cc(CO)c1 -US20080119518A1,1,C[O-].Cc1cccc(Cl)n1>>COc1cccc(C)n1 -US06369236B1,1,COCCOc1cc(Br)ccc1CBr.O=Cc1[nH]c(-c2ccccc2)nc1Cl>>COCCOc1cc(Br)ccc1Cn1c(-c2ccccc2)nc(Cl)c1C=O -US20120046292A1,6,O=C(OCc1ccccc1)c1ccc(OC2CCC3(CC2)OCCO3)cc1>>O=C1CCC(Oc2ccc(C(=O)OCc3ccccc3)cc2)CC1 -US20130144054A1,2,C[C@H](N)CO.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>C[C@@H](CO)NS(=O)(=O)c1ccccc1[N+](=O)[O-] -US05128448,3,Brc1cnc2ccccc2c1.C=CC(=O)OC>>COC(=O)/C=C/c1cnc2ccccc2c1 -US20100144714A1,1,CC(C)CC1C(=O)N(Cc2ccc(N3CCNCC3)cc2)c2nc3ccccc3c(=O)n21.CCI>>CCN1CCN(c2ccc(CN3C(=O)C(CC(C)C)n4c3nc3ccccc3c4=O)cc2)CC1 -US20120101116A1,6,COC(=O)/C=C/CN(C)C>>CN(C)C/C=C/C(=O)O -US20140329799A1,3,CCCC[Sn](CCCC)(CCCC)c1nc2ccccc2s1.COc1nc(N2CCOCC2)nc(N[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1I>>COc1nc(N2CCOCC2)nc(N[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1-c1nc2ccccc2s1 -US07863305B2,3,CC1(C)OC(=O)CC(=O)O1.COc1cccc2[nH]cc(C=O)c12>>COc1cccc2[nH]cc(C=C3C(=O)OC(C)(C)OC3=O)c12 -US08703805B2,3,Cn1cc(Br)c(-c2ccc(-c3cccc(S(C)(=O)=O)c3)s2)n1.OB(O)c1ccccc1Cl>>Cn1cc(-c2ccccc2Cl)c(-c2ccc(-c3cccc(S(C)(=O)=O)c3)s2)n1 -US05990102,8,O=C(CN1C(=O)CC1SCc1ccccc1)NCCCCCCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>O=C(CN1C(=O)CC1S(=O)Cc1ccccc1)NCCCCCCc1ccccc1 -US07867774B2,1,CN1CCOCC1.COCCOc1nc(Cl)nc(OCCOC)n1>>COCCOc1nc(OCCOC)nc([N+]2(C)CCOCC2)n1 -US07671043B2,1,CC(C)Cc1ccc(-c2noc(-c3ccc(C=O)cc3)n2)cc1.CCOC(=O)[C@@H]1C[C@H](N)C1>>CCOC(=O)[C@@H]1C[C@H](NCc2ccc(-c3nc(-c4ccc(CC(C)C)cc4)no3)cc2)C1 -US20120302753A1,1,Brc1ccc2c3ccccc3n(C3CCCCO3)c2c1.c1cn[nH]c1>>c1ccc2c(c1)c1ccc(-n3cccn3)cc1n2C1CCCCO1 -US07879835B2,1,C1COCCN1.CO/C=C(/C(=O)OC)c1ccccc1COc1cccc(C=O)c1>>CO/C=C(/C(=O)OC)c1ccccc1COc1cccc(CN2CCOCC2)c1 -US20040006112A1,1,COc1ccc(CCl)cc1.O=Cc1ccc(O)c(O)c1>>COc1ccc(COc2ccc(C=O)cc2O)cc1 -US08697697B2,6,CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)c1ccc2c(-c3[nH]ncc3-c3cccc(Cl)c3)c[nH]c2n1>>OCCN(Cc1ccccc1)c1ccc2c(-c3[nH]ncc3-c3cccc(Cl)c3)c[nH]c2n1 -US20130196998A1,6,CC(C)(C)OC(=O)CCN1CCC2(CC1)COc1cc(/C=C/c3c(Cl)cccc3Cl)ccc12>>O=C(O)CCN1CCC2(CC1)COc1cc(/C=C/c3c(Cl)cccc3Cl)ccc12 -US20030119670A1,2,CS(=O)(=O)Cl.Cc1ccc(-c2ccccc2)cc1CO>>Cc1ccc(-c2ccccc2)cc1COS(C)(=O)=O -US07094798B1,1,CN.O=C1NC(=O)c2c1c(-c1ccccc1)cc1c2c2cc(O)ccc2n1CCCBr>>CNCCCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4)cc21)C(=O)NC3=O -US20050245592A1,7,COC(=O)c1ccc(C)nc1>>Cc1ccc(CO)cn1 -US20100240702A1,1,COC(=O)CCC(C)=O.Nc1ccccc1N>>COC(=O)CCC(C)Nc1ccccc1N -US08871189B2,6,COC(=O)C1(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(C(=O)O)(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)CC1 -US08440710B2,1,O=[N+]([O-])c1ccc(Cl)nc1.OCC(F)(F)F>>O=[N+]([O-])c1ccc(OCC(F)(F)F)nc1 -US20090030023A1,1,FCCI.Nc1nc(-c2ccco2)c(-c2ccc(=O)[nH]c2)c(-c2ccco2)n1>>Nc1nc(-c2ccco2)c(-c2ccc(=O)n(CCF)c2)c(-c2ccco2)n1 -US08048909B2,2,Cc1[nH]ccc1C=O.O=S(=O)(Cl)c1cccnc1>>Cc1c(C=O)ccn1S(=O)(=O)c1cccnc1 -US20070027201A1,2,Cn1c(C#N)ccc1-c1ccc(N)cc1.O=C(Cl)c1ccco1>>Cn1c(C#N)ccc1-c1ccc(NC(=O)c2ccco2)cc1 -US20150183824A1,6,CCCC(NC(=O)OC(C)(C)C)C(OC)(OC)C(=O)NC1CC1>>CCCC(N)C(OC)(OC)C(=O)NC1CC1 -US20150105367A1,1,CC(N)=O.CCc1nc2cc(Cl)ncc2cc1-c1ccc(F)c(N)c1>>CCc1nc2cc(NC(C)=O)ncc2cc1-c1ccc(F)c(N)c1 -US06429214B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCO>>CC(C)(C)OC(=O)NCCO -US05591762,6,CCc1nc2c(C)cc(-c3cn(CCOC)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCc1nc2c(C)cc(-c3cn(CCOC)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20150158837A1,1,CC(C)(C)O.O=CC1=C[C@H]2CC(O)O[C@H]2C1>>CC(C)(C)OC1C[C@@H]2C=C(C=O)C[C@@H]2O1 -US04792628,1,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.Cc1cc(C)c2c(c1O)C(N)CC2>>Cc1cc(C)c2c(c1O)C(NCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CC2 -US07557213B2,1,Cc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1C.FC(F)(F)c1ccc(CBr)o1>>Cc1ccc(C(=O)c2cn(Cc3ccc(C(F)(F)F)o3)c3ccccc3c2=O)cc1C -US06277849B1,2,CCS(=O)(=O)N[C@H](C(=O)O)C(C)C.COc1cc(CCN)ccc1O>>CCS(=O)(=O)N[C@H](C(=O)NCCc1ccc(O)c(OC)c1)C(C)C -US20090124706A1,1,C=Cc1ccc(CCl)cc1.O=C1NC(=O)c2ccccc21>>C=Cc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 -US04539150,6,CCCCCCCCC(NC1CSc2ccccc2N(CC(=O)OC(C)(C)C)C1=O)C(=O)OCC>>CCCCCCCCC(NC1CSc2ccccc2N(CC(=O)O)C1=O)C(=O)OCC -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12.O=Cc1ccsc1>>FC(F)(F)c1nnc2ccc(N3CCN(Cc4ccsc4)CC3)nn12 -US07713994B2,7,CC1CN(c2ccc([N+](=O)[O-])cc2)CC(C)N1>>CC1CN(c2ccc(N)cc2)CC(C)N1 -US05880162,2,CC(=O)Cl.CC(C)(C=C(F)CO)c1ccc(OC(F)(F)F)cc1>>CC(=O)OCC(F)=CC(C)(C)c1ccc(OC(F)(F)F)cc1 -US05506256,8,O=C(OCc1ccccc1)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(O)CS(=O)c1ccccc1>>O=C(CS(=O)c1ccccc1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 -US20110237791A1,7,Cc1ccc(/C(=C/C2CCCC2)c2ccc(S(=O)(=O)C3CC3)cc2)[nH]c1=O>>Cc1ccc(C(CC2CCCC2)c2ccc(S(=O)(=O)C3CC3)cc2)[nH]c1=O -US20070105919A1,1,C=CC(=O)c1sc(NC(=O)OC(C)(C)C)nc1-c1ccco1.CO>>COCCC(=O)c1sc(NC(=O)OC(C)(C)C)nc1-c1ccco1 -US05364871,3,CC(=O)c1cccc(C=O)n1.N#CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=O)c1cccc(/C=C/C#N)n1 -US20130040930A1,1,CC(C)(C)OC(=O)N1CNC(=O)C1.Cc1cnc(N2CCN(C(=O)c3ccc(I)cc3)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CN(C(=O)OC(C)(C)C)CC4=O)cc3)CC2)c(C)c1 -US20150218150A1,2,CN1Cc2cc(-c3ccc(-c4cccc(N)c4)s3)ccc2C1=O.O=S(=O)(Cl)c1ccc(F)cc1F>>CN1Cc2cc(-c3ccc(-c4cccc(NS(=O)(=O)c5ccc(F)cc5F)c4)s3)ccc2C1=O -US20060246099A1,1,BrCCOCc1ccccc1.c1ccc(CCCN2CCNCC2)cc1>>c1ccc(CCCN2CCN(CCOCc3ccccc3)CC2)cc1 -US07935721B2,9,O=C1Nc2ccccc2C1(O)c1cc(Br)ccc1O>>O=C1Nc2ccccc2C1c1cc(Br)ccc1O -US20120288492A1,2,COc1cnc(-c2ccc(N)cc2)nc1N1CCOCC1.O=C(Cl)Oc1ccccc1>>COc1cnc(-c2ccc(NC(=O)Oc3ccccc3)cc2)nc1N1CCOCC1 -US20090318493A1,8,CCCC1(C(O)c2ccc3ccccc3n2)CCN(C(=O)OC(C)(C)C)CC1>>CCCC1(C(=O)c2ccc3ccccc3n2)CCN(C(=O)OC(C)(C)C)CC1 -US04175203,2,CCO.O=C(O)c1ccc(CCCBr)cc1>>CCOC(=O)c1ccc(CCCBr)cc1 -US08124649B2,3,CC1(C)OB(c2ccc(OCCN3CCOCC3)cc2)OC1(C)C.O=C1Nc2ccc(Cl)cc2C1=Cc1ccc(Br)o1>>O=C1Nc2ccc(Cl)cc2C1=Cc1ccc(-c2ccc(OCCN3CCOCC3)cc2)o1 -US05821240,7,N#CC12CCN(CC1)CC2>>NCC12CCN(CC1)CC2 -US04902691,2,CN1CC(C(=O)O)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21.NCc1cccnc1>>CN1C[C@H](C(=O)NCc2cccnc2)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21 -US20040072839A1,2,CCN=C=O.COc1ccccc1N1CCN(CCC(c2ccccc2F)C(O)C2CCCCC2)CC1>>CCNC(=O)OC(C1CCCCC1)C(CCN1CCN(c2ccccc2OC)CC1)c1ccccc1F -US20090111810A1,2,Nc1ncnc(Nc2ccc(OCc3ccccc3)c(Cl)c2)c1C(=O)O.OCCN1CCOCC1>>Nc1ncnc(Nc2ccc(OCc3ccccc3)c(Cl)c2)c1C(=O)OCCN1CCOCC1 -US06566390B2,7,O=[N+]([O-])c1ccc2c(c1)OS(=O)(=O)N2>>Nc1ccc2c(c1)OS(=O)(=O)N2 -US20060122197A1,1,CCN(CC)C(=O)COc1ccc(Cl)cc1.O=C(N[C@H]1CCCNC1)C12CC3CC(C1)C(O)C(C3)C2>>CCN(CC)C(=O)COc1ccc(N2CCC[C@H](NC(=O)C34CC5CC(C3)C(O)C(C5)C4)C2)cc1 -US04082778,1,Nc1ccc([N+](=O)[O-])cc1Cl.O=C1c2ccccc2C(=O)c2c(Cl)cc(Cl)cc21>>O=C1c2ccccc2C(=O)c2c(Nc3ccc([N+](=O)[O-])cc3Cl)cc(Cl)cc21 -US07795283B2,2,COC(=O)C(=O)Cl.COC(=O)C[C@@H]1CC[C@@H](c2ccc(N)cn2)CC1>>COC(=O)C[C@@H]1CC[C@@H](c2ccc(NC(=O)C(=O)OC)cn2)CC1 -US08163752B2,7,Nc1cc(Cl)nc(Cl)c1[N+](=O)[O-]>>Nc1cc(Cl)nc(Cl)c1N -US20080139631A1,1,CCc1cc2c(C(F)(F)F)c(C#N)ccc2[nH]1.FC(F)(F)c1cccc(-c2nc(CCl)no2)c1>>CCc1cc2c(C(F)(F)F)c(C#N)ccc2n1Cc1noc(-c2cccc(C(F)(F)F)c2)n1 -US20070049587A1,7,N#Cc1cc(N2CCOCC2=O)ccc1[N+](=O)[O-]>>N#Cc1cc(N2CCOCC2=O)ccc1N -US04324743,2,N[C@@H](CCC(=O)NCCS(=O)(=O)O)C(=O)O.O=C(Cl)c1ccccc1>>O=C(CC[C@H](NC(=O)c1ccccc1)C(=O)O)NCCS(=O)(=O)O -US20120115895A1,6,CN1C(=O)N(Cc2cc(Cl)ccc2F)C(=O)C12C(=O)N(CC(=O)OC(C)(C)C)c1ccc(Cl)cc12>>CN1C(=O)N(Cc2cc(Cl)ccc2F)C(=O)C12C(=O)N(CC(=O)O)c1ccc(Cl)cc12 -US20090253699A1,4,CC(C)c1ccc(C(=O)CBr)cc1.CCOC(=O)c1cccc(C(N)=S)c1>>CCOC(=O)c1cccc(-c2nc(-c3ccc(C(C)C)cc3)cs2)c1 -US20060276505A1,2,CC1(C(=O)O)CCCCC1.NNc1cccc2ncccc12>>CC1(C(=O)NNc2cccc3ncccc23)CCCCC1 -US20070066624A1,6,Cc1cccc([C@@H]2CNC(=O)N2C2CCN(Cc3ccc(Oc4ccc(OCC(=O)OC(C)(C)C)cc4)nc3C)CC2)c1>>Cc1cccc([C@@H]2CNC(=O)N2C2CCN(Cc3ccc(Oc4ccc(OCC(=O)O)cc4)nc3C)CC2)c1 -US06492348B1,8,CCC(O)CNC(=O)[C@H]1O[C@@H](OC)[C@@H]2OC(C)(C)O[C@H]21>>CCC(=O)CNC(=O)[C@H]1O[C@@H](OC)[C@@H]2OC(C)(C)O[C@H]21 -US07368471B2,1,BrCc1ccccc1.Brc1ccc2cc[nH]c2c1>>Brc1ccc2ccn(Cc3ccccc3)c2c1 -US06929789B2,3,C1=CCC=C1.O=C1OC(=O)C2=C1CCC2>>O=C1OC(=O)C23CCCC12C1C=CC3C1 -US04725689,8,O=C1c2ccccc2C(=O)N1c1ncc(C(Cl)Cl)nc1CO>>O=Cc1nc(C(Cl)Cl)cnc1N1C(=O)c2ccccc2C1=O -US07115598B2,8,OCc1ccc(Cl)cc1O>>O=Cc1ccc(Cl)cc1O -US20130203986A1,1,CC(C)N.Cc1nc(Cl)nc(Cl)c1[N+](=O)[O-]>>Cc1nc(Cl)nc(NC(C)C)c1[N+](=O)[O-] -US04288605,2,CCC(=O)Cl.O=C(CBr)Nc1cccc(O)c1>>CCC(=O)Oc1cccc(NC(=O)CBr)c1 -US20090197875A1,1,Cc1onc(-c2ccccc2)c1-c1nnc(-c2ccc(Cl)nc2)o1.NCCO>>Cc1onc(-c2ccccc2)c1-c1nnc(-c2ccc(NCCO)nc2)o1 -US20100113540A1,2,COCCCCCCCCO.CS(=O)(=O)Cl>>COCCCCCCCCOS(C)(=O)=O -US08399436B2,1,FC(F)(F)c1cc(Cl)ccc1CBr.O=C(Nc1cc[nH]n1)c1c(F)cccc1F>>O=C(Nc1ccn(Cc2ccc(Cl)cc2C(F)(F)F)n1)c1c(F)cccc1F -US07056918B2,1,COC(=O)c1ccc(F)c([N+](=O)[O-])c1.NC1CCC1>>COC(=O)c1ccc(NC2CCC2)c([N+](=O)[O-])c1 -US20060229314A1,1,CCOC(=O)c1c(N2CCN(C(=O)c3cccs3)CC2)c2sccc2[nH]c1=O.Fc1cccc(CBr)c1>>CCOC(=O)c1c(N2CCN(C(=O)c3cccs3)CC2)c2sccc2n(Cc2cccc(F)c2)c1=O -US03998850,3,CC(C)(C)C(=O)Cl.CC1(c2ccc(Br)cc2)OCCO1>>CC(C)(C)C(=O)c1ccc(C2(C)OCCO2)cc1 -US20150065343A1,6,CCOC(=O)c1sc(/C=C/C(=O)OC(C)(C)C)cc1C>>CCOC(=O)c1sc(/C=C/C(=O)O)cc1C -US06444672B1,6,NCc1ccc2c(NC(=O)c3ccccc3)nccc2c1>>NCc1ccc2c(N)nccc2c1 -US08049015B2,10,COc1ncc(CBr)cc1Br.O=C1CCC(=O)N1Br>>COc1ncc(C(Br)Br)cc1Br -US08623866B2,2,CN.Cc1nc(C(=O)O)c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)s1>>CNC(=O)c1nc(C)sc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 -US20090029979A1,1,BrCc1ccccc1.OC1(c2ccc(Br)cc2)CCNCC1>>OC1(c2ccc(Br)cc2)CCN(Cc2ccccc2)CC1 -US20120329775A1,6,CN1C(=O)CSc2cc(-c3ccc(C[C@@H](C#N)NC(=O)C4(NC(=O)OC(C)(C)C)CCOCC4)cc3)ccc21>>CN1C(=O)CSc2cc(-c3ccc(C[C@@H](C#N)NC(=O)C4(N)CCOCC4)cc3)ccc21 -US20150057260A1,3,C#C[C@]1(O)CCN(C)C1=O.NC(=O)c1nc(-c2ccc(F)c(Br)c2)c(F)cc1N>>CN1CC[C@@](O)(C#Cc2cc(-c3nc(C(N)=O)c(N)cc3F)ccc2F)C1=O -US06713645B1,6,COC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1cccc(I)c1>>NC(=O)c1cccc2c1c1c(OCC(=O)O)cccc1n2Cc1cccc(I)c1 -US20050038068A1,5,CC(=O)c1ccc(O)cc1.COCCl>>COCOc1ccc(C(C)=O)cc1 -US05371081,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.c1ccc2c(c1)Nc1ccccc1O2>>O=C(N1c2ccccc2Oc2ccccc21)C(F)(F)F -US06166226,1,Brc1cccc2ccccc12.OC1CCCCC1>>c1ccc2c(OC3CCCCC3)cccc2c1 -US20060287363A1,2,Nc1ccc(F)c([N+](=O)[O-])c1.O=C(Cl)c1ccc(F)cc1Cl>>O=C(Nc1ccc(F)c([N+](=O)[O-])c1)c1ccc(F)cc1Cl -US20060234997A1,7,CC(C)(C#N)c1ccccc1[N+](=O)[O-]>>CC(C)(CN)c1ccccc1[N+](=O)[O-] -US04636509,1,O=C(CBr)c1ccccc1.O=c1ncc(Br)c[nH]1>>O=C(Cn1cc(Br)cnc1=O)c1ccccc1 -US07582673B2,3,Nc1ccc(Br)cc1[N+](=O)[O-].OB(O)c1ccncc1>>Nc1ccc(-c2ccncc2)cc1[N+](=O)[O-] -US20140350002A1,2,CN1c2nc(C3CC4CNCC4C3)ccc2N(CC2CC2(F)F)S1(=O)=O.C[C@@H](O)C(=O)O>>C[C@@H](O)C(=O)N1CC2CC(c3ccc4c(n3)N(C)S(=O)(=O)N4CC3CC3(F)F)CC2C1 -US20140142097A1,3,Nc1ncc(Br)cc1C(=O)Nc1ccncc1.O=C(O)CCc1ccc(B(O)O)cc1>>Nc1ncc(-c2ccc(CCC(=O)O)cc2)cc1C(=O)Nc1ccncc1 -US20030158245A1,6,CCOC(=O)c1sc(Oc2ncccn2)c2c1CCc1cnn(C)c1-2>>Cn1ncc2c1-c1c(Oc3ncccn3)sc(C(=O)O)c1CC2 -US05491153,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCC(=O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1c(NCC(=O)c2ccc(C(F)(F)F)cc2)c2c(Cl)cc(Cl)cc2n1C(=O)OC(C)(C)C -US20110288066A1,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)NC(C)C)cc1Br>>Cc1ccc(S(=O)(=O)NC(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C -US20050032873A1,1,CC(=O)CCc1c[nH]c2ccc(F)cc12.NC(=O)c1ccc(F)c2c1CC(N)CO2>>CC(CCc1c[nH]c2ccc(F)cc12)NC1COc2c(F)ccc(C(N)=O)c2C1 -US20150252044A1,2,NCCCn1ccnc1.O=C(O)c1ccc2cncc(Br)c2n1>>O=C(NCCCn1ccnc1)c1ccc2cncc(Br)c2n1 -US06846819B1,2,CN.O=C(O)c1cc2ccccc2o1>>CNC(=O)c1cc2ccccc2o1 -US20100120785A1,8,Cc1nn(-c2ccccn2)c(C)c1CO>>Cc1nn(-c2ccccn2)c(C)c1C=O -US20130196974A1,2,CC(C)(Br)C(=O)Cl.Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(N)c2c1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NC(=O)C(C)(C)Br)c2c1 -US06359145B1,1,CCCC(Br)C(=O)OCC.NC(=O)c1c[nH]cn1>>CCCC(C(=O)OCC)n1cnc(C(N)=O)c1 -US08354426B2,1,CCOC(CBr)OCC.O=c1ccc2ncc(F)cc2[nH]1>>CCOC(Cn1c(=O)ccc2ncc(F)cc21)OCC -US20130310562A1,6,c1ccc(Oc2ccc(Nc3ccnc4cc(-c5ccc(C6OCCO6)o5)ccc34)cc2)cc1>>O=Cc1ccc(-c2ccc3c(Nc4ccc(Oc5ccccc5)cc4)ccnc3c2)o1 -US06107307,7,CN1C2C=C(c3c[nH]c4cc(F)ccc34)CC1CC2>>CN1C2CCC1CC(c1c[nH]c3cc(F)ccc13)C2 -US20100048551A1,3,NC(=O)c1cnc(N)c2c1sc1cc(Br)ccc12.OB(O)c1ccccc1>>NC(=O)c1cnc(N)c2c1sc1cc(-c3ccccc3)ccc12 -US08507509B2,1,COC(=O)C(Cl)SC.Oc1ccc2ncc(Br)cc2c1>>COC(=O)C(Oc1ccc2ncc(Br)cc2c1)SC -US04327095,2,CN1CCN(C(=O)Cl)CC1.COc1ccc2ccc(N3C(=O)C4=C(SCC(OC)CS4)C3O)nc2n1>>COc1ccc2ccc(N3C(=O)C4=C(SCC(OC)CS4)C3OC(=O)N3CCN(C)CC3)nc2n1 -US04522646,1,ClCc1c(Cl)ccc2cc(Cl)cnc12.O=C[O-]>>O=COCc1c(Cl)ccc2cc(Cl)cnc12 -US04999378,7,CCOC(=O)C1CCCC1Nc1ccc(Cl)cc1>>OCC1CCCC1Nc1ccc(Cl)cc1 -US07320994B2,3,CCCC[Sn](CCCC)(CCCC)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1C.O=C(c1ccccc1Cl)c1cccnc1Br>>Cc1c(-c2ncccc2C(=O)c2ccccc2Cl)nnn1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090042896A1,7,CCC(=O)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1>>CCC(O)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1 -US05919936,2,CN1CCC(c2c[nH]c3ccc(N)nc23)CC1.O=C(Cl)c1c(F)c(F)c(F)c(F)c1F>>CN1CCC(c2c[nH]c3ccc(NC(=O)c4c(F)c(F)c(F)c(F)c4F)nc23)CC1 -US05750735,2,CC(O)C1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(SC3COC(CO)C3)C(C)C12.CS(=O)(=O)Cl>>CC(O)C1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(SC3COC(COS(C)(=O)=O)C3)C(C)C12 -US20120316147A1,2,CC(C)CC(N)c1cccnn1.O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1>>CC(C)C[C@@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)c1cccnn1 -US20040209897A1,1,C1COCCN1.O=Cc1ccc(F)c(F)c1>>O=Cc1ccc(N2CCOCC2)c(F)c1 -US20100197681A1,2,CCOC(=O)CC(=O)Cl.Nc1nc2cccc(-c3ccoc3)n2n1>>CCOC(=O)CC(=O)Nc1nc2cccc(-c3ccoc3)n2n1 -US20020137741A1,1,CCOC(=O)c1cn(C)c2cnc3cc(F)c(F)cc3c2c1=O.Fc1ccc(N2CCNCC2)cc1>>CCOC(=O)c1cn(C)c2cnc3cc(N4CCN(c5ccc(F)cc5)CC4)c(F)cc3c2c1=O -US20140155391A1,1,BrCC1CC1.O=Cc1ccc(OCc2ccccc2)c(O)c1>>O=Cc1ccc(OCc2ccccc2)c(OCC2CC2)c1 -US20070185120A1,2,C1CC2CNCCN2C1.CCOC(=O)c1cc2cc(Cl)sc2[nH]1>>O=C(c1cc2cc(Cl)sc2[nH]1)N1CCN2CCCC2C1 -US05510531,2,CC(C)C[C@H](N)C(=O)O.O=C(F)OC12CC3CC(CC(C3)C1)C2>>CC(C)C[C@H](NC(=O)OC12CC3CC(CC(C3)C1)C2)C(=O)O -US04818431,1,CCCCCC1CCC(c2ccc(O)cc2)OC1.CCCCCCI>>CCCCCCOc1ccc(C2CCC(CCCCC)CO2)cc1 -US20090099187A1,2,COc1ccc(Cl)cc1N.COc1ccc(S(=O)(=O)Cl)c2c1C[C@@H](NC(=O)C(F)(F)F)CO2>>COc1ccc(Cl)cc1NS(=O)(=O)c1ccc(OC)c2c1OC[C@H](NC(=O)C(F)(F)F)C2 -US20050113450A1,2,COC(=O)c1cc(Br)ccc1N.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cc(Br)ccc1NC(=O)c1ccc(S(=O)(=O)Cl)cc1 -US20050250797A1,1,CC(C)(O)C#Cc1cc(Cl)c(N)c2c1OCO2.COc1cc2ncnc(Cl)c2cc1OC>>COc1cc2ncnc(Nc3c(Cl)cc(C#CC(C)(C)O)c4c3OCO4)c2cc1OC -US07622474B2,7,O=c1[nH]c2ccccc2c(=O)n1-c1ccc([N+](=O)[O-])cc1Br>>Nc1ccc(-n2c(=O)[nH]c3ccccc3c2=O)c(Br)c1 -US20050143452A1,9,[N-]=[N+]=NCC1Cc2c(C(F)(F)F)ccc(Cl)c2O1>>NCC1Cc2c(C(F)(F)F)ccc(Cl)c2O1 -US09000025B2,1,CCOC(=O)c1cccc(Sc2c(C)[nH]c3c(F)c(Cl)ccc23)c1.CCn1cc(Br)cn1>>CCOC(=O)c1cccc(Sc2c(C)n(-c3cnn(CC)c3)c3c(F)c(Cl)ccc23)c1 -US20100210704A1,8,CC(=O)Nc1cc(OCC(F)(F)C(F)(F)F)nn1-c1cc(SCC(F)(F)Cl)c(C)cc1F.O=C(OO)c1cccc(Cl)c1>>CC(=O)Nc1cc(OCC(F)(F)C(F)(F)F)nn1-c1cc(S(=O)CC(F)(F)Cl)c(C)cc1F -US20100035891A1,2,COCC(C)O.CS(=O)(=O)Cl>>COCC(C)OS(C)(=O)=O -US20110039848A1,1,C1COCCN1.Cc1cc(Cl)nnc1Cl>>Cc1cc(N2CCOCC2)nnc1Cl -US20150225365A1,6,CC(C)(C)OC(=O)N1CCc2cc(-c3cncc(F)c3)ccc21>>Fc1cncc(-c2ccc3c(c2)CCN3)c1 -US06265446B1,5,CC(C)CNNC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)C(F)(F)F)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C -US20090005353A1,1,CC(C)(C)N1C(=O)C(NCCCBr)=C(c2ccccc2)S1(=O)=O.O=C(O)c1ccc(O)cc1>>CC(C)(C)N1C(=O)C(NCCCOC(=O)c2ccc(O)cc2)=C(c2ccccc2)S1(=O)=O -US09023846B2,9,CC(C)(C)c1cc(C(=O)O)oc1Br>>CC(C)(C)c1coc(C(=O)O)c1 -US08716326B2,3,Nc1ccccc1NC(=O)c1ccc(CN2Cc3c(Br)cccc3C2=O)cc1.OB(O)c1cc(F)cc(F)c1>>Nc1ccccc1NC(=O)c1ccc(CN2Cc3c(cccc3-c3cc(F)cc(F)c3)C2=O)cc1 -US20030134838A1,1,CNc1nc(Nc2ccc(Cl)c(Cl)c2)ncc1NC(=O)N(C)CCO>>CNc1nc(Nc2ccc(Cl)c(Cl)c2)ncc1N1CCN(C)C1=O -US05670699,6,CC(C)(C)OC(=O)N[C@H](Cc1cscn1)C(=O)O>>N[C@H](Cc1cscn1)C(=O)O -US20150164904A1,7,O=[N+]([O-])c1ncn(-c2cccc(C(F)(F)F)c2)n1>>Nc1ncn(-c2cccc(C(F)(F)F)c2)n1 -US09120807B2,1,CCN.O=C(c1cccs1)c1nc(NCc2cccnc2)nc2cc(Cl)sc12>>CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1 -US20070232615A1,1,CN(Cc1cn2c(F)cccc2n1)[C@H]1CCCc2cccnc21.OCCN1CCCCC1>>CN(Cc1cn2c(OCCN3CCCCC3)cccc2n1)[C@H]1CCCc2cccnc21 -US20150274747A1,1,Clc1ncc(Cl)c(Cl)n1.NC1COC2C(OCCO)COC12>>OCCOC1COC2C(Nc3nc(Cl)ncc3Cl)COC12 -US07279470B2,6,COc1ccc(N2CCC(C)(C)CC2)cn1>>CC1(C)CCN(c2ccc(O)nc2)CC1 -US05580863,1,O=C(O)C=CC(=O)c1ccccc1O>>O=C1CC(C(=O)O)Oc2ccccc21 -US20150210682A1,1,CC(C)(CO)CBr.CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2C(C)(C)C>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCC(C)(C)CO)cc1CC2C(C)(C)C -US04644063,1,CC(C)CC(N)C(O)c1ccccc1.ClCCCN1CCCCC1>>CC(C)CC(NCCCN1CCCCC1)C(O)c1ccccc1 -US05164514,2,O=C1CCCN1.O=S(=O)(Cl)c1ccccc1C1CCCCC1>>O=C1CCCN1S(=O)(=O)c1ccccc1C1CCCCC1 -US20070123572A1,1,NCCCBr.O=Cc1ccc2c(c1)OCO2>>BrCCCNCc1ccc2c(c1)OCO2 -US08680108B2,3,CON(C)C(=O)c1cc(Cl)c2cccnc2c1N1CCC(O[Si](C)(C)C(C)(C)C)CC1.C[Mg+]>>CC(=O)c1cc(Cl)c2cccnc2c1N1CCC(O[Si](C)(C)C(C)(C)C)CC1 -US04642308,1,Cc1cccc(C)c1O.Nc1ccc2ccc(Cl)nc2n1>>Cc1cccc(C)c1Oc1ccc2ccc(N)nc2n1 -US20140235855A1,3,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C=O)CC1.COc1ccc2ncc(Cl)c(CC[P+](c3ccccc3)(c3ccccc3)c3ccccc3)c2c1>>COc1ccc2ncc(Cl)c(CC=C[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)c2c1 -US20100305066A1,3,C#C[Si](CC)(CC)CC.Ic1ccc2[nH]ccc2c1>>CC[Si](C#Cc1ccc2[nH]ccc2c1)(CC)CC -US08193356B2,2,O=C(Cl)CC1CCOCC1.O=c1cc(O)c2cccnc2n1-c1ccccc1>>O=C(CC1CCOCC1)Oc1cc(=O)n(-c2ccccc2)c2ncccc12 -US20080188484A1,6,CCOC(=O)c1cc2cc(OC)c(Cl)cc2[nH]1>>CCOC(=O)c1cc2cc(O)c(Cl)cc2[nH]1 -US08754114B2,2,N#CCC1(n2cc(-c3cnn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CNC1.O=C(Cl)N1CCCC1>>N#CCC1(n2cc(-c3cnn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CN(C(=O)N2CCCC2)C1 -US20070054916A1,6,Cc1ccccc1-c1ccc2nc(N[C@@H](C)Cc3cccc([C@H](C)NC(=O)OC(C)(C)C)c3)ncc2c1>>Cc1ccccc1-c1ccc2nc(N[C@@H](C)Cc3cccc([C@H](C)N)c3)ncc2c1 -US20090099161A1,3,C=CS(C)(=O)=O.COCc1nc2c(N)nc3cc(Br)ccc3c2n1CC(C)(C)O>>COCc1nc2c(N)nc3cc(C=CS(C)(=O)=O)ccc3c2n1CC(C)(C)O -US20140329797A1,1,CC(C)(O)Cc1cccc(COS(C)(=O)=O)c1.O=c1ccc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)c[nH]1>>CC(C)(O)Cc1cccc(Cn2cc(-c3nc(-c4ccc(OC(F)(F)F)cc4)no3)ccc2=O)c1 -US04691019,1,FC(F)(F)c1cccc(C2=CCNCC2)c1.N#CCCl>>N#CCN1CC=C(c2cccc(C(F)(F)F)c2)CC1 -US08394858B2,2,CC(C)(C)OC(=O)NC1(C(=O)O)CCC(=O)CC1.C[C@@H](N)c1ccc(F)cc1>>C[C@@H](NC(=O)C1(NC(=O)OC(C)(C)C)CCC(=O)CC1)c1ccc(F)cc1 -US07767691B2,1,CCBr.N#CC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2>>CC[N+]12CCC(C(C#N)(c3ccccc3)c3ccccc3)(CC1)C2 -US20120035237A1,1,CCCCOc1ccccc1CBr.CCOC(=O)c1cc[nH]n1>>CCCCOc1ccccc1Cn1ccc(C(=O)OCC)n1 -US08173650B2,1,Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CBr)n(C)c2n1.NC1CCC(O)CC1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CNC3CCC(O)CC3)n(C)c2n1 -US04997847,2,NCCCCCC(=O)O.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(O)CCCCCNS(=O)(=O)c1ccc(Cl)cc1 -US07435815B2,2,CN(C)c1cccc(N(CC(=O)O)S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1.OCCCNCc1ccccn1>>CN(C)c1cccc(N(CC(=O)N(CCCO)Cc2ccccn2)S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1 -US20150148313A1,7,CN(Cc1cc([N+](=O)[O-])ccc1S(=O)(=O)C(C)(C)C)C(=O)OC(C)(C)C>>CN(Cc1cc(N)ccc1S(=O)(=O)C(C)(C)C)C(=O)OC(C)(C)C -US07772238B2,2,CCOC(=O)c1cc2ccc(CC(=O)O)cc2s1.COc1ccc(C(=O)NN)cc1>>CCOC(=O)c1cc2ccc(CC(=O)NNC(=O)c3ccc(OC)cc3)cc2s1 -US09040522B2,2,C[C@H]1CNCCN1C1CC1.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)N3CCN(C4CC4)[C@@H](C)C3)cn2)c1O -US07423175B2,6,CC(C)(C)OC(=O)NCCOc1ccc(F)cc1>>NCCOc1ccc(F)cc1 -US08716483B2,6,COC(=O)C1(SC)CCN(Cc2ccccc2)C1>>COC(=O)C1(SC)CCNC1 -US06969711B2,2,CC(C)c1cccc(C(C)C)c1N=C=O.NCCN1CCN(CCO)CC1>>CC(C)c1cccc(C(C)C)c1NC(=O)NCCN1CCN(CCO)CC1 -US20150284386A1,1,BrCCCOC1CC1.CC1(C)C(=O)Nc2cc(Br)ccc21>>CC1(C)C(=O)N(CCCOC2CC2)c2cc(Br)ccc21 -US20150018547A1,6,COC(=O)Cc1csc2cc(OCc3ccc(C(F)(F)F)nc3C)cc(C)c12>>Cc1nc(C(F)(F)F)ccc1COc1cc(C)c2c(CC(=O)O)csc2c1 -US06413947B1,7,O=[N+]([O-])c1ccc(CNc2ccccn2)cc1>>Nc1ccc(CNc2ccccn2)cc1 -US20150057260A1,3,C#C[C@]1(O)CCN(C)C1=O.CCOC(=O)c1nc(-c2cccc(Br)c2)nc2c1CC(C)(C)CC2>>CCOC(=O)c1nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)nc2c1CC(C)(C)CC2 -US20090062531A1,1,CN(C)C(=S)Cl.COC(=O)Cc1ccc(F)c(O)c1>>COC(=O)Cc1ccc(F)c(OC(=S)N(C)C)c1 -US04847256,7,N#Cc1cnn2c1NCC=C2c1cccc(F)c1>>N#Cc1cnn2c1NCCC2c1cccc(F)c1 -US08227492B2,1,CCI.CS(=O)(=NC(=O)C1CCNCC1)c1ccccc1-c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1>>CCN1CCC(C(=O)N=S(C)(=O)c2ccccc2-c2ccc(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cn3)cc2)CC1 -US04704462,7,COc1ccc(C=CC(=O)O)cc1OC>>COc1ccc(C=CCO)cc1OC -US20110118262A1,6,COC(=O)c1cc(C(F)(F)F)c(OCc2ccccc2)cc1C>>COC(=O)c1cc(C(F)(F)F)c(O)cc1C -US20040229874A1,1,CC(C)(C)OC(=O)N1CCN(c2ccccc2-c2ccc(COS(C)(=O)=O)cc2)CC1.Fc1ccc2[nH]ccc2c1>>CC(C)(C)OC(=O)N1CCN(c2ccccc2-c2ccc(Cn3ccc4cc(F)ccc43)cc2)CC1 -US20120309762A1,8,O=C(OCc1cncs1)N(Cc1ccccc1)CC(O)CN(Cc1ccccc1)C(=O)OCc1cncs1>>O=C(CN(Cc1ccccc1)C(=O)OCc1cncs1)CN(Cc1ccccc1)C(=O)OCc1cncs1 -US08354398B2,1,CC(C)(C)OC(=O)C1CNC1.Fc1cc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)ccc1CBr>>CC(C)(C)OC(=O)C1CN(Cc2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2F)C1 -US20090226398A1,1,CS(=O)(=O)OCc1ccc(Br)cn1.Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F>>Fc1cccc(-c2nc3cnn(Cc4ccc(Br)cn4)cc-3n2)c1F -US07897774B2,10,COc1ccc2nccc(C)c2c1.O=C1CCC(=O)N1Br>>COc1ccc2nccc(CBr)c2c1 -US03933841,9,Nc1ccc2nc(Oc3ccccc3)sc2c1.S=C(Cl)Cl>>S=C=Nc1ccc2nc(Oc3ccccc3)sc2c1 -US05932601,1,BrCc1ccccc1.CCOC(=O)CCCCc1ccc(O)c(OC)c1>>CCOC(=O)CCCCc1ccc(OCc2ccccc2)c(OC)c1 -US08415381B2,1,N#Cc1cc(NCc2cccc(F)c2)nc(-c2cc(F)ncc2Cl)c1.N[C@H]1CC[C@H](N)CC1>>N#Cc1cc(NCc2cccc(F)c2)nc(-c2cc(N[C@@H]3CC[C@@H](N)CC3)ncc2Cl)c1 -US20150266848A1,7,CC(C)(C)C(=O)OCC[C@@H]1OC2(CCCC2)O[C@H]1c1ccccc1Cl>>OCC[C@@H]1OC2(CCCC2)O[C@H]1c1ccccc1Cl -US07727985B2,2,CC(C)(C)OC(=O)N1CCOC[C@H]1C(=O)O.Nc1cc(Cl)cc2c1[nH]c1cnccc12>>CC(C)(C)OC(=O)N1CCOC[C@H]1C(=O)Nc1cc(Cl)cc2c1[nH]c1cnccc12 -US20100069388A1,7,CCOC(=O)c1cnc(NCCOc2ccccc2)c(Cl)c1>>OCc1cnc(NCCOc2ccccc2)c(Cl)c1 -US20070088041A1,3,CC(C)(C)OC(=O)n1c(B(O)O)cc2ccccc21.COc1nnc(-c2ccncc2)cc1I>>COc1nnc(-c2ccncc2)cc1-c1cc2ccccc2n1C(=O)OC(C)(C)C -US20090054407A1,1,CI.O=C(O)c1ccc2[nH]ccc2c1>>Cn1ccc2cc(C(=O)O)ccc21 -US08415370B2,9,O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C1(O)c1ccc(Br)cc1O>>O=C1C(c2ccc(Br)cc2O)c2ccccc2N1C(c1ccccc1)c1ccccc1 -US07425634B2,8,Cc1c(OCC2OCC3(CC3)CO2)ccnc1CSc1nc2ccccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>Cc1c(OCC2OCC3(CC3)CO2)ccnc1CS(=O)c1nc2ccccc2[nH]1 -US05872116,1,COC(=O)CCCCCBr.FC(F)(F)c1cc(CO[C@H]2OCCN[C@@H]2c2ccccc2)cc(C(F)(F)F)c1>>COC(=O)CCCCCN1CCO[C@H](OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]1c1ccccc1 -US20040121965A1,2,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](N)C(C)(C)C.COc1ccccc1C(C)(C)[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1OC)C(C)(C)C -US20120108583A1,2,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1.NCC1CC1>>CC1(C)Cc2c(c(C(=O)NCC3CC3)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1 -US20040242572A1,2,CCCC(C)c1ccc(C(=O)O)cc1.NCCc1ccc(CN2CCCC2)cc1>>CCCC(C)c1ccc(C(=O)NCCc2ccc(CN3CCCC3)cc2)cc1 -US20110212956A1,7,CC1(c2cccnc2CC#N)OCCO1>>CC1(c2cccnc2CCN)OCCO1 -US20090215776A1,3,CC1(C)OB(c2cnn(C3CCOCC3)c2)OC1(C)C.Nc1cc(-c2cncc(Br)c2)cc(-c2ccccn2)n1>>Nc1cc(-c2cncc(-c3cnn(C4CCOCC4)c3)c2)cc(-c2ccccn2)n1 -US05025015,2,CNc1ccc(Cl)cc1Cc1ccccc1.O=C(Br)CBr>>CN(C(=O)CBr)c1ccc(Cl)cc1Cc1ccccc1 -US08063035B2,1,CC(NC(=O)OC(C)(C)C)c1ccc(F)cc1Br.CI>>CC(c1ccc(F)cc1Br)N(C)C(=O)OC(C)(C)C -US20120053180A1,9,CS(=O)(=O)c1ccc(-c2cc(F)c(OC3CCC(N=[N+]=[N-])CC3)c(F)c2)cc1>>CS(=O)(=O)c1ccc(-c2cc(F)c(OC3CCC(N)CC3)c(F)c2)cc1 -US20110230497A1,6,CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2ccc(-c3ccccc3)cc2)CC1>>O=C(CC1CCNCC1)Nc1ccc(-c2ccccc2)cc1 -US07749998B2,2,CC(C)(Nc1ccc(Cl)c(Cl)c1)C(=O)O.CNC(CN1CCCC1)c1ccc(-c2ccccc2)cc1>>CN(C(=O)C(C)(C)Nc1ccc(Cl)c(Cl)c1)C(CN1CCCC1)c1ccc(-c2ccccc2)cc1 -US20150126522A1,6,COC(=O)c1cc(Cl)cc(OC(C)C)c1C>>Cc1c(OC(C)C)cc(Cl)cc1C(=O)O -US20150099882A1,6,CCOC(=O)CCNC(=O)c1ccc(C(CCC(F)(F)F)Nc2cnc3ccccc3c2)cc1>>O=C(O)CCNC(=O)c1ccc(C(CCC(F)(F)F)Nc2cnc3ccccc3c2)cc1 -US03953499,7,CCCCCC(C)=CCC=C(C)CC#CCCCCCCCl>>CCCCCC(C)=CCC=C(C)CC=CCCCCCCCl -US20060194790A1,6,CC(C)(C)OC(=O)N1CC2CCC1CC2Cc1ccc(Cl)c(Cl)c1>>Clc1ccc(CC2CC3CCC2CN3)cc1Cl -US08829040B2,7,CCOC(=O)c1ccc(-n2cc(C#N)c3ccc([N+](=O)[O-])cc32)cc1>>CCOC(=O)c1ccc(-n2cc(C#N)c3ccc(N)cc32)cc1 -US06358995B1,6,COc1cc(C)c(F)cc1C>>Cc1cc(F)c(C)cc1O -US06642239B2,2,CCCN1CCN(c2ccc(C(=O)O)cc2)CC1.N#CCNC(=O)C1(N)CCCCC1>>CCCN1CCN(c2ccc(C(=O)NC3(C(=O)NCC#N)CCCCC3)cc2)CC1 -US06136823,1,CN.O=C(O)c1cn(-c2nc(NCCO)c(F)cc2F)c2c(Cl)c(F)c(F)cc2c1=O>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3nc(NCCO)c(F)cc3F)c2c1Cl -US20120088746A1,2,CC1(c2ccc3cc(C(=O)O)ccc3n2)CC1.Cc1cc([C@@H](C)N)c(F)cc1NS(C)(=O)=O>>Cc1cc([C@@H](C)NC(=O)c2ccc3nc(C4(C)CC4)ccc3c2)c(F)cc1NS(C)(=O)=O -US20060178515A1,2,COc1ccc(CCN)cc1OC.O=C(O)C=Cc1cc(F)ccc1F>>COc1ccc(CCNC(=O)C=Cc2cc(F)ccc2F)cc1OC -US20040038975A1,6,C[C@H]1C[C@H](NC(=O)OC(C)(C)C)CN(Cc2ccccc2)C1>>C[C@@H]1CNC[C@@H](NC(=O)OC(C)(C)C)C1 -US20150232444A1,6,COc1ccc(NC(=O)OCc2ccccc2)cc1S(=O)(=O)N1CCC(N2CCC(C)CC2)CC1>>COc1ccc(N)cc1S(=O)(=O)N1CCC(N2CCC(C)CC2)CC1 -US20060235021A1,3,Fc1cnc(-c2cc(-c3ccc(F)c(Br)c3)cnn2)c(F)c1.OB(O)c1ccccc1C(F)(F)F>>Fc1cnc(-c2cc(-c3ccc(F)c(-c4ccccc4C(F)(F)F)c3)cnn2)c(F)c1 -US20130116236A1,1,CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1.CC1COCCN1>>CC1COCCN1c1nc(C(C)(C)C)nc2c1nnn2Cc1ccccc1Cl -US04166819,4,N#CCOc1ccc(C(=O)c2ccccc2)c(Cl)c1Cl.[N-]=[N+]=[N-]>>O=C(c1ccccc1)c1ccc(OCc2nnn[nH]2)c(Cl)c1Cl -US09073922B2,1,CN(C)C(=O)CCl.COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CC4CNCC4C3)cc12>>COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CC4CN(CC(=O)N(C)C)CC4C3)cc12 -US20100130490A1,1,Clc1ncnc2ccccc12.Oc1ccc2nc(N[C@@H]3CCCC[C@H]3O)sc2c1>>O[C@@H]1CCCC[C@H]1Nc1nc2ccc(Oc3ncnc4ccccc34)cc2s1 -US20130096118A1,7,Cc1c(NC(=O)OCc2ccccc2)cccc1C(C[N+](=O)[O-])c1c[nH]c2cc(Br)ccc12>>Cc1c(NC(=O)OCc2ccccc2)cccc1C(CN)c1c[nH]c2cc(Br)ccc12 -US05665777,2,N#Cc1ccc(-c2ccc(OCCCC(=O)O)cc2)cc1.O=C1N[C@@H](Cc2ccccc2)CO1>>N#Cc1ccc(-c2ccc(OCCCC(=O)N3C(=O)OC[C@@H]3Cc3ccccc3)cc2)cc1 -US20120142705A1,6,COC(=O)C(CC(C)C)N1C(=O)C(=O)c2cc(OC(F)(F)F)ccc21>>CC(C)CC(C(=O)O)N1C(=O)C(=O)c2cc(OC(F)(F)F)ccc21 -US07964603B2,7,Cc1ccc2c(N3CCN(C(=O)OC(C)(C)C)CC3)cccc2n1>>CC1CCc2c(cccc2N2CCN(C(=O)OC(C)(C)C)CC2)N1 -US20130267726A1,2,CC(C)O.O=C(O)c1ccccc1O>>CC(C)OC(=O)c1ccccc1O -US20140249126A1,6,CCOC(=O)c1cn(CC)c2c(F)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc2c1=O>>CCn1cc(C(=O)O)c(=O)c2cc(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)c(F)c21 -US20150232459A1,1,COC(=O)NCCCn1nc(C(C)=O)cc1-c1ccccn1.NC1CC1>>COC(=O)NCCCn1nc(C(C)NC2CC2)cc1-c1ccccn1 -US04035369,6,CC(=O)N1CCC(C2(c3ccc(F)cc3)OCCO2)CC1>>Fc1ccc(C2(C3CCNCC3)OCCO2)cc1 -US20140051679A1,3,CN1CCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.O=C(N[C@H](c1ccccc1)C1CC1)c1ccc2[nH]nc(I)c2c1>>CN1CCC(Oc2ccc(-c3n[nH]c4ccc(C(=O)N[C@H](c5ccccc5)C5CC5)cc34)cc2)CC1 -US20100150866A1,6,C=CCCCCCC1(S(=O)(=O)NC(=O)OC(C)(C)C)CC1>>C=CCCCCCC1(S(N)(=O)=O)CC1 -US05817599,2,CCCCCCCCCCCCCCCCOC(=O)Cl.NCCN1CCOCC1>>CCCCCCCCCCCCCCCCOC(=O)NCCN1CCOCC1 -US20120115893A1,6,CC(C)(C)OC(=O)NCc1cc(C(F)(F)F)nn1CC1CC1>>NCc1cc(C(F)(F)F)nn1CC1CC1 -US04356118,6,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)C(C)C>>CC(C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)C(C)C -US20150031690A1,2,C[C@@]1(c2cc(N)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1.O=C(O)c1ccc(OC(F)F)cn1>>C[C@@]1(c2cc(NC(=O)c3ccc(OC(F)F)cn3)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1 -US20140275084A1,3,Cn1cnc(-c2cc(C#N)ccn2)c1Br.OB(O)c1ccc(F)cc1OCc1ccccc1>>Cn1cnc(-c2cc(C#N)ccn2)c1-c1ccc(F)cc1OCc1ccccc1 -US20120225909A1,7,CCOC(=O)/C=C/c1nn(C2CCCCO2)c2cc(OCc3ccccc3)ccc12>>CCOC(=O)CCc1nn(C2CCCCO2)c2cc(OCc3ccccc3)ccc12 -US20080139558A1,1,Nc1ccc(N2CCCCC2)cc1.O=c1cc(CBr)c2ccc(F)c(F)c2[nH]1>>O=c1cc(CNc2ccc(N3CCCCC3)cc2)c2ccc(F)c(F)c2[nH]1 -US20110230467A1,9,NC(=O)c1cnc(Nc2ccccn2)cc1N[C@@H]1CCN(c2ncc(Br)cn2)C[C@@H]1F.[C-]#N>>N#Cc1cnc(N2CC[C@@H](Nc3cc(Nc4ccccn4)ncc3C(N)=O)[C@@H](F)C2)nc1 -US05922742,3,CS(=O)(=O)c1ccc(C2=C(Br)C(=O)CC2)cc1.C[Sn](C)(C)c1ccc(Br)cn1>>CS(=O)(=O)c1ccc(C2=C(c3ccc(Br)cn3)C(=O)CC2)cc1 -US20120077812A1,1,CC(C)OC(=O)N1CCC(COS(C)(=O)=O)CC1.CS(=O)(=O)c1ccc(-c2ccc(O)c(F)c2)nc1>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(S(C)(=O)=O)cn3)cc2F)CC1 -US06335459B1,6,COC(=O)COc1cccc(COC(=O)N(c2ccccc2)c2ccccc2)c1Cl>>O=C(O)COc1cccc(COC(=O)N(c2ccccc2)c2ccccc2)c1Cl -US20090275590A1,6,Cn1c2c(c3ccc(-n4ccc(OCc5ccc(Cl)cc5)cc4=O)cc31)CN(C(=O)OC(C)(C)C)CC2>>Cn1c2c(c3ccc(-n4ccc(OCc5ccc(Cl)cc5)cc4=O)cc31)CNCC2 -US20070249670A1,2,CC(C)(C)OC(=O)c1cc(Br)sc1N.O=C=Nc1c(Cl)cc(OC(F)(F)F)cc1Cl>>CC(C)(C)OC(=O)c1cc(Br)sc1NC(=O)Nc1c(Cl)cc(OC(F)(F)F)cc1Cl -US20080214495A1,6,CC(C)(C)OC(=O)N1CCC(C(=O)c2ccc(S(=O)(=O)c3ccc4cc(Br)ccc4c3)cc2)CC1>>O=C(c1ccc(S(=O)(=O)c2ccc3cc(Br)ccc3c2)cc1)C1CCNCC1 -US20040067999A1,7,CC(C)c1c([N+](=O)[O-])ccc2c1c1ccccc1n2C(C)C>>CC(C)c1c(N)ccc2c1c1ccccc1n2C(C)C -US20050197371A1,2,CC(C)(C)c1cc(N=C=O)no1.Nc1ccc(OCc2ccccc2F)cc1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(OCc3ccccc3F)cc2)no1 -US20150065534A1,6,COC(=O)[C@H](CNC(=O)c1cccc(OCCCN)c1)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C>>Cc1nc(NCCCc2cccc(O)c2)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccc(OCCCN)c1)C(=O)O -US05324451,1,CCCI.CCOC(=O)[C@H](C)O>>CCCO[C@@H](C)C(=O)OCC -US20090048444A1,3,CSc1ccccc1B(O)O.O=c1ccc2c(Cl)nc(NC(CO)CO)nc2n1-c1c(F)cccc1F>>CSc1ccccc1-c1nc(NC(CO)CO)nc2c1ccc(=O)n2-c1c(F)cccc1F -US20130178631A1,2,CS(=O)(=O)Cl.OCCC#Cc1ccccn1>>CS(=O)(=O)OCCC#Cc1ccccn1 -US04999451,10,CC=CC(C)(C)C(C)C(=O)OCC.O=C1CCC(=O)N1Br>>CCOC(=O)C(C)C(C)(C)C=CCBr -US20120040942A1,1,C1COCCN1.CC(=O)c1ccc(F)c(C(F)(F)F)c1>>CC(=O)c1ccc(N2CCOCC2)c(C(F)(F)F)c1 -US05994344,2,CCOC(CCCN)OCC.O=C(Cl)OCc1ccccc1>>CCOC(CCCNC(=O)OCc1ccccc1)OCC -US07557213B2,3,CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O.[Mg+]c1ccc(Cl)cc1>>O=C(c1ccc(Cl)cc1)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O -US20060189629A1,1,Nc1ccc(OCCOc2ccccn2)cc1.O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>O=C(O)c1ccc(Nc2ccc(OCCOc3ccccn3)cc2)c([N+](=O)[O-])c1 -US08420824B2,2,Nc1cccc(C=O)c1.O=C=Nc1cc(C(F)(F)F)ccc1F>>O=Cc1cccc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)c1 -US07250410B2,7,CCN1C(=O)C(Cc2ccccc2C#N)N=C(c2ccccc2)c2cc(OC)c(OC)cc21>>CCN1C(=O)C(Cc2ccccc2CN)N=C(c2ccccc2)c2cc(OC)c(OC)cc21 -US20070203205A1,1,CN(C)CCCO.O=S(=O)(c1ccc(/C=C/c2ccc(F)cc2F)nc1)c1ccccc1F>>CN(C)CCCOc1ccccc1S(=O)(=O)c1ccc(/C=C/c2ccc(F)cc2F)nc1 -US20140249104A1,6,CC(C)(C)OC(=O)N1CC=C(C#CC2CC2)CC1>>C(#CC1CC1)C1=CCNCC1 -US20110071199A1,7,O=C(O)c1cc(F)c(Cl)cc1F>>OCc1cc(F)c(Cl)cc1F -US04153619,9,COc1ccc(CBr)c2oc(Br)c(-c3ccccc3F)c12.[C-]#N>>COc1ccc(CC#N)c2oc(Br)c(-c3ccccc3F)c12 -US20140243298A1,6,C=C(C)[C@@H]1CC[C@]2(NCCN3CCC(S(C)(=O)=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C=C6CCC(F)(C(=O)OCC)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCCN3CCC(S(C)(=O)=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C=C6CCC(F)(C(=O)O)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US08592452B2,3,CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1c(F)ccc(C2OCCO2)c1Cl>>CC=Cc1c(F)ccc(C2OCCO2)c1Cl -US20100227273A1,1,C=C(C)C(=O)O.OC1Cc2cccc3cccc1c23>>C=C(C)C(=O)OC1Cc2cccc3cccc1c23 -US20070232682A1,3,C#CC(C)C.Nc1ccccc1I>>CC(C)C#Cc1ccccc1N -US06407094B1,3,C#Cc1ccccc1.CC(C)(C)OC(=O)Nc1cc(CO)c(I)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(CO)c(C#Cc2ccccc2)cc1[N+](=O)[O-] -US04939138,8,O=[N+]([O-])c1ccccc1OCC(O)CN1CCOCC1>>O=C(COc1ccccc1[N+](=O)[O-])CN1CCOCC1 -US20140235704A1,3,C#CC(C)(C)C.COC(=O)c1sc(Br)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)[C@@H]1CC[C@@H](O)CC1>>COC(=O)c1sc(C#CC(C)(C)C)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)[C@@H]1CC[C@@H](O)CC1 -US20040236109A1,1,CC(=O)N1c2ccc(O)cc2C(C)(c2ccccc2)CC1(C)C.ClCC1CC1>>CC(=O)N1c2ccc(OCC3CC3)cc2C(C)(c2ccccc2)CC1(C)C -US20140371238A1,6,Cc1cccc(NC2CCN(C(=O)OC(C)(C)C)CC2)n1>>Cc1cccc(NC2CCNCC2)n1 -US20050267150A1,2,CC1C(=O)N(C(=O)[C@H](C)N)c2cccc(N)c2-c2ccccc21.CCCCC(C)C(=O)O>>CCCCC(C)C(=O)N[C@@H](C)C(=O)N1C(=O)C(C)c2ccccc2-c2c(N)cccc21 -US20120309966A1,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)c1cc2ccsc2n1C.Cc1nccn2c([C@@H]3CC[C@@H](N4CCN(C)CC4)CC3)nc(Br)c12>>COc1cc(-c2nc([C@@H]3CC[C@@H](N4CCN(C)CC4)CC3)n3ccnc(C)c23)ccc1NC(=O)c1cc2ccsc2n1C -US20150080364A1,6,COC(=O)c1ccc(C)cc1CN1CCN(C(=O)OC(C)(C)C)CC1>>Cc1ccc(C(=O)O)c(CN2CCN(C(=O)OC(C)(C)C)CC2)c1 -US20120190679A1,6,CC(C)(C)OC(=O)NC(CCNS(C)(=O)=O)c1ccc(Cl)cc1>>CS(=O)(=O)NCCC(N)c1ccc(Cl)cc1 -US20130053363A1,4,CC(C)(C)OC(=O)N1CCC(=O)CC1.C[S+](C)(C)=O>>CC(C)(C)OC(=O)N1CCC2(CC1)CO2 -US20090275564A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CC[C@H](N)C(=O)O>>COC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)O -US20090200514A1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=CCC[C@@H]1CC[C@@H](COc2cccc(F)c2F)CC1>>C=CCC[C@@H]1CC[C@@H](COc2cccc(F)c2F)CC1 -US20080045526A1,3,CCC1OC(=O)c2ncccc21.O=C1Cc2cc(F)ccc2N1>>CCC1OC(=C2C(=O)Nc3ccc(F)cc32)c2ncccc21 -US07745479B2,1,CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCOCC4)cc3c2)CC1.N#Cc1ccc(B(O)O)cc1>>CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCOCC2)n3-c2ccc(C#N)cc2)CC1 -US20120196884A1,4,CN(c1ccc(NC(=O)Nc2ccccc2)cc1)S(=O)(=O)c1ccc(C(=O)CC(=O)C(F)(F)F)s1.NN>>CN(c1ccc(NC(=O)Nc2ccccc2)cc1)S(=O)(=O)c1ccc(-c2cc(C(F)(F)F)n[nH]2)s1 -US07319097B2,6,CC(C)(C)OC(=O)N1CCCN(c2ccc(S(=O)(=O)Nc3ccccc3)cc2NS(C)(=O)=O)CC1>>CS(=O)(=O)Nc1cc(S(=O)(=O)Nc2ccccc2)ccc1N1CCCNCC1 -US20120295897A1,9,Cc1cc(O)c(C2(O)C(=O)N(C(c3ccccc3)c3ccccc3)c3ccccc32)cc1C>>Cc1cc(O)c(C2C(=O)N(C(c3ccccc3)c3ccccc3)c3ccccc32)cc1C -US20140350019A1,7,Cc1cc(-c2cccc(F)c2)cc(C(=O)Nc2c(C)ccc(O)c2C)c1C>>Cc1cc(-c2cccc(F)c2)cc(CNc2c(C)ccc(O)c2C)c1C -US20150158878A1,2,CC(=O)OC(C)=O.Nc1ccc2c(c1)OC(F)(F)O2>>CC(=O)Nc1ccc2c(c1)OC(F)(F)O2 -US04422982,1,CCOP(=O)(CNC=O)OCC.COC(=O)CCl>>CCOP(=O)(CN(C=O)CC(=O)OC)OCC -US20130064770A1,1,COc1ccccc1N1CCNCC1.O=C1CNC(=O)N1CCCCCl>>COc1ccccc1N1CCN(CCCCN2C(=O)CNC2=O)CC1 -US20110071199A1,1,BrCc1ccc(Br)cc1.NC(=O)[C@@H](CC1CC1)NS(=O)(=O)c1ccc(Cl)s1>>NC(=O)[C@@H](CC1CC1)N(Cc1ccc(Br)cc1)S(=O)(=O)c1ccc(Cl)s1 -US20080015193A1,2,Cc1nc2ccc(C(=O)O)cc2[nH]1.NCC(=O)c1ccccc1>>Cc1nc2ccc(C(=O)NCC(=O)c3ccccc3)cc2[nH]1 -US05977141,1,O=C(O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc(F)cc1.c1ccc(C2CCNCC2)cc1>>O=C(O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc(N2CCC(c3ccccc3)CC2)cc1 -US20110207701A1,10,Cc1ccc(C#N)cc1Br.O=C1CCC(=O)N1Br>>N#Cc1ccc(CBr)c(Br)c1 -US08940716B2,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CCCc1cnc(N2CCC(Oc3nc4ncc(Br)cc4s3)CC2)nc1>>CCCc1cnc(N2CCC(Oc3nc4ncc(C5=CCN(C(=O)OC(C)(C)C)CC5)cc4s3)CC2)nc1 -US20050004031A1,1,CC(C)(C)OC(=O)CBr.COC(=O)CCS>>COC(=O)CCSCC(=O)OC(C)(C)C -US04128658,7,CNC(=C[N+](=O)[O-])SC>>CNC(C[N+](=O)[O-])SC -US07935721B2,3,CN1C(=O)C2(COc3cc4c(cc32)OCO4)c2c(Br)cccc21.OB(O)c1ccc(F)nc1>>CN1C(=O)C2(COc3cc4c(cc32)OCO4)c2c(-c3ccc(F)nc3)cccc21 -US06790842B1,1,CNCCCSCc1ccccn1.C[C@]12C[C@H](c3ccc(CCI)cc3)[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O>>CN(CCCSCc1ccccn1)CCc1ccc([C@H]2C[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]3CCc4cc(O)ccc4[C@@H]23)cc1 -US20080319078A1,6,CCOC(=O)COc1ccc(C(CC)=C(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1>>CCC(=C(c1ccc(OC)cc1)c1ccc(OC)cc1)c1ccc(OCC(=O)O)cc1 -US20070225340A1,1,C=C(Cl)CO.CCOC(=O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2O)n1>>C=C(Cl)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(C(=O)OCC)n1 -US20040157886A1,2,Cc1ccc(CC2CCNCC2)cc1.O=C(Cl)CCl>>Cc1ccc(CC2CCN(C(=O)CCl)CC2)cc1 -US20120329775A1,9,CN1C(=O)CSc2cc(-c3ccc(C[C@H](NC(=O)C4(NC(=O)OC(C)(C)C)CCOCC4)C(N)=O)cc3)ccc21>>CN1C(=O)CSc2cc(-c3ccc(C[C@@H](C#N)NC(=O)C4(NC(=O)OC(C)(C)C)CCOCC4)cc3)ccc21 -US20100249124A1,6,CC(c1ccc(C(=O)NCC(=O)OC(C)(C)C)cc1Cl)C(O)(c1ccc2oc(=O)n(C)c2c1)C(F)(F)F>>CC(c1ccc(C(=O)NCC(=O)O)cc1Cl)C(O)(c1ccc2oc(=O)n(C)c2c1)C(F)(F)F -US08575153B2,1,CCOC(=O)c1cnc(Cl)cc1NC(=O)C(F)(F)F.COc1ccc(CNc2ccc(N3CCOCC3)nc2)cc1>>CCOC(=O)c1cnc(N(Cc2ccc(OC)cc2)c2ccc(N3CCOCC3)nc2)cc1NC(=O)C(F)(F)F -US20110021501A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1(c2ccc(Cl)cc2)CCNCC1>>CC(C)(C)OC(=O)N1CCC(CO)(c2ccc(Cl)cc2)CC1 -US20020013230A1,9,COc1cnc(Cl)nc1Cl.NN>>COc1cnc(Cl)nc1NN -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.O=C=Nc1ccc(Br)cc1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)Nc3ccc(Br)cc3)CC2)nc1C(F)(F)F -US20120059028A1,6,CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccc(F)cc1)CCCC3>>CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(F)cc1)CCCC3 -US20120264753A1,1,CCCCc1nc(-c2ccc(F)cc2)c(C=O)[nH]1.N#Cc1ccccc1-c1ccc(CBr)cc1>>CCCCc1nc(-c2ccc(F)cc2)c(C=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US05612377,9,NO.O=C1CCCCCCC1>>ON=C1CCCCCCC1 -US05541229,6,CCCCc1nc2cc(Cl)ccc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2cc(Cl)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20120004269A1,3,C#CCNC(=O)C(F)(F)F.CCCC(O)(C#Cc1cccc(Br)c1)CCC>>CCCC(O)(C#Cc1cccc(C#CCNC(=O)C(F)(F)F)c1)CCC -US06201121B1,2,CCO.O=C(O)Cn1c(=O)[nH]c(=O)c2ccc(Cl)cc21>>CCOC(=O)Cn1c(=O)[nH]c(=O)c2ccc(Cl)cc21 -US05104897,2,CC(=O)Cl.CN(C)Cc1ccccc1Sc1ccc(Cl)cc1CO>>CC(=O)OCc1cc(Cl)ccc1Sc1ccccc1CN(C)C -US07442791B2,1,CC(C)(C)OC(=O)CBr.CN([C@@H]1CC[C@@H](O)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1>>CN([C@@H]1CC[C@@H](OCC(=O)OC(C)(C)C)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1 -US20020173548A1,2,CO.Nc1ccc(C(=O)O)c(O)c1>>COC(=O)c1ccc(N)cc1O -US20050203158A1,1,CI.O=C(Nc1ccc(F)c([N+](=O)[O-])c1)C1CCCCC1>>CN(C(=O)C1CCCCC1)c1ccc(F)c([N+](=O)[O-])c1 -US05902803,2,CC(=O)OC(C)=O.NCc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12>>CC(=O)NCc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12 -US03952003,1,CC(=O)N(C1=C(Cl)C(=O)c2c(cnn2C)C1=O)C(C)C.CCO>>CCOC1=C(N(C(C)=O)C(C)C)C(=O)c2cnn(C)c2C1=O -US20130217664A1,6,CCc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1N(C)c1cc2c(cn1)ncn2C>>CCc1cc(C2CCNCC2)ccc1N(C)c1cc2c(cn1)ncn2C -US03932465,2,O=C(O)Cc1ccco1.OCCBr>>O=C(Cc1ccco1)OCCBr -US06803381B1,2,COCCc1nnc(N)o1.O=C(O)C(c1ccccc1)c1ccccc1>>COCCc1nnc(NC(=O)C(c2ccccc2)c2ccccc2)o1 -US05273986,3,O=Cc1cccc([N+](=O)[O-])c1.c1ccc([P+](Cc2csc(C3CCC3)n2)(c2ccccc2)c2ccccc2)cc1>>O=[N+]([O-])c1cccc(/C=C/c2csc(C3CCC3)n2)c1 -US04333759,1,CC(=O)O.CC1(C)c2cc(C#N)ccc2OC1Cl>>CC(=O)OC1Oc2ccc(C#N)cc2C1(C)C -US20130217666A1,3,CC(C)(O)Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.NC(=O)c1nc2n(c1I)C1CC(C1)c1cc(F)c(Br)cc1-2>>CC(C)(O)Cn1cc(-c2c(C(N)=O)nc3n2C2CC(C2)c2cc(F)c(Br)cc2-3)cn1 -US08513239B2,2,CCOc1nc(C(C)(C)C)ncc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.OCCN1CCNCC1>>CCOc1nc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCO)CC1 -US07964627B2,1,CN(C)CCCl.COc1ccc2c(c1)c(C)cn2S(=O)(=O)c1ccc(OC)c(N)c1>>COc1ccc2c(c1)c(C)cn2S(=O)(=O)c1ccc(OC)c(NCCN(C)C)c1 -US05684034,7,Cc1c(CC(N)=O)c2cc([N+](=O)[O-])ccc2n1Cc1ccccc1>>Cc1c(CC(N)=O)c2cc(N)ccc2n1Cc1ccccc1 -US04337341,1,BrCC1CCCO1.Oc1cccc(C23CCCC2CNCC3)c1>>Oc1cccc(C23CCCC2CN(CC2CCCO2)CC3)c1 -US20140329858A1,6,COc1ccc(CN2C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)[C@@H]3COCC[C@H]32)cc1>>N#Cc1ccc(N2C(=O)N[C@@H]3CCOC[C@H]32)cc1C(F)(F)F -US20120053197A1,3,CC(C)[Mg+].O=Cc1ccc(I)cc1>>CC(C)C(O)c1ccc(I)cc1 -US05834461,2,Nc1ccc(C(=O)N2Cc3ccccc3Sc3ccccc32)cc1.O=C(Cl)c1ccccc1Cl>>O=C(Nc1ccc(C(=O)N2Cc3ccccc3Sc3ccccc32)cc1)c1ccccc1Cl -US20080306055A1,1,CCOC(=O)CC1CCNCC1.O=Cc1ccn(-c2ccc(C(F)(F)F)cc2)c1>>CCOC(=O)CC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1 -US20100216816A1,1,CC(C)(C)[S@](N)=O.O=Cc1cnc(OCC(F)(F)F)cn1>>CC(C)(C)S(=O)N=Cc1cnc(OCC(F)(F)F)cn1 -US20110034460A1,3,C1COCCN1.C=O.O=Cc1ccc[nH]1>>O=Cc1cc(CN2CCOCC2)c[nH]1 -US20150191452A1,6,CC(C)(C)OC(=O)N1CC[C@H](c2ccc(O)cc2)[C@@H](O)C1>>Oc1ccc([C@H]2CCNC[C@@H]2O)cc1 -US05599587,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCCCCCO>>CC(C)(C)OC(=O)NCCCCCCO -US20080312231A1,2,COC(=O)C1Cc2ccccc2N1.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1>>COC(=O)C1Cc2ccccc2N1S(=O)(=O)c1ccc(Cl)c(Cl)c1 -US08138197B2,2,COc1cc(C(=O)O)cc(-c2ccc3[nH]ccc3c2)c1.O=C1CC2(CCNCC2)Oc2ccc(-c3nnn[nH]3)cc21>>COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4nnn[nH]4)ccc2O3)cc(-c2ccc3[nH]ccc3c2)c1 -US06821967B2,1,O=C(NCc1ccc(F)cc1)C1(CCCCBr)c2ccccc2Oc2ccccc21.c1ccc2nc(N3CCNCC3)ccc2c1>>O=C(NCc1ccc(F)cc1)C1(CCCCN2CCN(c3ccc4ccccc4n3)CC2)c2ccccc2Oc2ccccc21 -US05498755,7,CC1(C)CC(C)(C)c2cc(C(=O)O)ccc2O1>>CC1(C)CC(C)(C)c2cc(CO)ccc2O1 -US08338590B2,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCCN1CCNCC1>>CCCN1CCN(C2CCN(C(=O)OC(C)(C)C)CC2)CC1 -US20100144700A1,2,CC(C)(C)OC(=O)N1CCC2CNCC21.O=C(O)c1ccoc1>>CC(C)(C)OC(=O)N1CCC2CN(C(=O)c3ccoc3)CC21 -US05646173,4,CC(=O)NCCN.COc1cccc2c1CCC(CC=O)C2=O>>COc1cccc2c1CCc1ccn(CCNC(C)=O)c1-2 -US20090176786A1,2,CN(C(=O)Cl)c1ccc(SC(F)(F)F)cc1F.CSCCN>>CSCCNC(=O)N(C)c1ccc(SC(F)(F)F)cc1F -US20090048291A1,6,CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2ccc(S(C)(=O)=O)cc2)CC1>>CS(=O)(=O)c1ccc(NC(=O)CC2CCNCC2)cc1 -US20140179672A1,2,CC1(N)CC1(C)N.Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)O)n2c1>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NC3(C)CC3(C)N)n2c1 -US20140005221A1,3,CC(C)Br.COC(=O)c1ccc2cc[nH]c2c1>>COC(=O)c1ccc2c(C(C)C)c[nH]c2c1 -US03972900,5,CCc1cccc2cc(C(C)=O)oc12.OCCO>>CCc1cccc2cc(C3(C)OCCO3)oc12 -US20090186876A1,2,CC(C)c1ccccc1N=C=O.CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)Nc3ccccc3C(C)C)CC2)nc1C(F)(F)F -US20110172442A1,2,COC(=O)[C@@H](N)Cc1ccc(OC)cc1.O=C(O)C=Cc1cc(F)ccc1F>>COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C=Cc1cc(F)ccc1F -US20100216750A1,6,COC(=O)CSCCCCc1ccccc1>>O=C(O)CSCCCCc1ccccc1 -US20140342989A1,9,CC(C)(C)[Si](C)(C)OCc1ccc(C(=O)C(F)(F)F)cc1.NO>>CC(C)(C)[Si](C)(C)OCc1ccc(C(=NO)C(F)(F)F)cc1 -US20080318991A1,3,CCNC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cn1.O=C1N([C@@H]2CC[C@H](O)CC2)CC[C@]12CCCN(c1ccc(Br)cc1F)C2>>CCNC(=O)c1ccc(-c2ccc(N3CCC[C@]4(CCN([C@@H]5CC[C@H](O)CC5)C4=O)C3)c(F)c2)cn1 -US09145355B2,3,CC1(C)O[C@H](c2ccc(I)cc2)[C@@H](CF)N1C(=O)C(Cl)Cl.OCc1ccc(B(O)O)cc1>>CC1(C)O[C@H](c2ccc(-c3ccc(CO)cc3)cc2)[C@@H](CF)N1C(=O)C(Cl)Cl -US20050256159A1,2,COc1cccc(C(=O)C2CCNCC2)c1.O=C(Cl)c1ccco1>>COc1cccc(C(=O)C2CCN(C(=O)c3ccco3)CC2)c1 -US20110319378A1,1,CC[C@@H](CNS(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1.CI>>CC[C@@H](CN(C)S(=O)(=O)CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cc(F)cc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US20100256134A1,2,Cc1ccc(C(F)(F)F)cc1Nc1c(C(=O)N2CCC(c3ccccc3)CC2)cnc2c(C(=O)O)cnn12.NS(=O)(=O)C1CC1>>Cc1ccc(C(F)(F)F)cc1Nc1c(C(=O)N2CCC(c3ccccc3)CC2)cnc2c(C(=O)NS(=O)(=O)C3CC3)cnn12 -US20050192294A1,6,CCOC(=O)c1ncccc1Nc1cc(C(C)(C)C)nn1-c1c(C)cccc1C>>Cc1cccc(C)c1-n1nc(C(C)(C)C)cc1Nc1cccnc1C(=O)O -US20100179139A1,2,CC(C)(C)OC(=O)N1CCC(N)CC1.O=S(=O)(Cl)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1CCC(NS(=O)(=O)c2ccc(Cl)nc2)CC1 -US07858640B2,9,COC(=O)COc1cc(C)cc2nc(Cl)c(Cc3ccc(Cl)cc3)c(C)c12>>COC(=O)COc1cc(C)cc2ncc(Cc3ccc(Cl)cc3)c(C)c12 -US04808480,1,C1=COCCC1.O=C(O)CCCCCCCCCCCO>>O=C(O)CCCCCCCCCCCOC1CCCCO1 -US06723720B2,1,Fc1cccc(F)c1-c1ncc(Cl)nn1.Oc1cccc(Cl)c1>>Fc1cccc(F)c1-c1ncc(Oc2cccc(Cl)c2)nn1 -US04398029,1,C1COCCN1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCOCC3)c(F)c21 -US20080051384A1,2,CO.Cc1sc(C(=O)O)cc1[N+](=O)[O-]>>COC(=O)c1cc([N+](=O)[O-])c(C)s1 -US04333940,6,CCCCCCCCCCCCCCCCNc1ccc(C(=O)NCC(=O)OCC)c(F)c1>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)NCC(=O)O)c(F)c1 -US20090209571A1,3,CCN(CC)C(=O)c1ccc(OC)cc1B(O)O.Cc1cccnc1Br>>CCN(CC)C(=O)c1ccc(OC)cc1-c1ncccc1C -US05990346,6,CCCC[C@@H](C)C[C@H](O)/C=C/[C@@H]1C(SCCCCCC(=O)OC)=CC[C@H]1O>>CCCC[C@@H](C)C[C@H](O)/C=C/[C@@H]1C(SCCCCCC(=O)O)=CC[C@H]1O -US08614206B2,7,CN(CC1CCN(c2c([N+](=O)[O-])cnn2C)CC1)C(=O)OC(C)(C)C>>CN(CC1CCN(c2c(N)cnn2C)CC1)C(=O)OC(C)(C)C -US08293757B2,1,Cc1ccc(N)cc1[N+](=O)[O-].Clc1ncc(Br)cn1>>Cc1ccc(Nc2ncc(Br)cn2)cc1[N+](=O)[O-] -US20110269734A1,1,Cc1cc(OCCCC2CCNCC2)ccc1C(=O)NCCO.Fc1cnc(Cl)nc1>>Cc1cc(OCCCC2CCN(c3ncc(F)cn3)CC2)ccc1C(=O)NCCO -US20150218092A1,1,C=CCBr.CC=C(Oc1ccc(C2CC2)cc1)C(=O)Nc1ccc(OCCOC2CCCCO2)c(CC)c1>>C=CCN(C(=O)C(=CC)Oc1ccc(C2CC2)cc1)c1ccc(OCCOC2CCCCO2)c(CC)c1 -US20120040954A1,4,COc1cc(N)c(C(N)=O)c(OC)c1.O=Cc1ccc(N2CCC(NC(=O)c3ccccc3)CC2)cc1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCC(NC(=O)c5ccccc5)CC4)cc3)nc2c1 -US05985899,2,CCCCOC(=O)N[C@@H](Cc1ccc(C#N)cc1)C(=O)O.CS(=O)(=O)N1CCNCC1>>CCCCOC(=O)N[C@@H](Cc1ccc(C#N)cc1)C(=O)N1CCN(S(C)(=O)=O)CC1 -US20140329771A1,6,CC(C)[C@H]1CC=CC[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)CCCC(=O)O1>>CC(C)[C@H]1CC=CC[C@H](C)[C@@H](O)CCCC(=O)O1 -US20150141464A1,9,CC(C)c1cccc([C@H](C)NC(=O)c2ccc3c(c2)ncn3Cc2ccc(Br)cc2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)c1cccc([C@H](C)NC(=O)c2ccc3c(c2)ncn3Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c1 -US06458781B1,2,CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)O.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1 -US20090270361A1,1,COC(=O)c1ccc(Cc2c(C)n[nH]c2C)cc1.N#Cc1ccc(F)cc1C(F)(F)F>>COC(=O)c1ccc(Cc2c(C)nn(-c3ccc(C#N)c(C(F)(F)F)c3)c2C)cc1 -US05340833,3,CN(C)C=O.Fc1cccc2ccccc12>>O=Cc1ccc2ccccc2c1F -US04279912,6,CCOC(=O)c1cn2c(ccc3ccccc32)n1>>O=C(O)c1cn2c(ccc3ccccc32)n1 -US06245769B1,7,COCCC(COC)Nc1cc(C)nc(Cl)c1[N+](=O)[O-]>>COCC[C@@H](COC)Nc1cc(C)nc(Cl)c1N -US08859545B2,7,CC(=O)N1CC(C)(C)c2ccc([N+](=O)[O-])cc21>>CC(=O)N1CC(C)(C)c2ccc(N)cc21 -US06265434B1,1,Nc1ccccc1N.O=CCCC1CCN(Cc2ccccc2)CC1>>Nc1ccccc1NCCCC1CCN(Cc2ccccc2)CC1 -US07326699B2,7,CCc1c(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc2n1[C@H]1C[C@@H](C(=O)OC)C1>>CCc1c(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc2n1[C@@H]1C[C@H](CO)C1 -US20020052376A1,6,COC(=O)c1ccc(C(OCCc2cncn2C)c2ccc(F)cc2)nc1-c1ccc(F)cc1>>Cn1cncc1CCOC(c1ccc(F)cc1)c1ccc(C(=O)O)c(-c2ccc(F)cc2)n1 -US20100113773A1,6,OC1([C@H]2CC[C@@H](c3cc(F)c(F)c(F)c3)N2Cc2ccccc2)CC1>>OC1([C@H]2CC[C@@H](c3cc(F)c(F)c(F)c3)N2)CC1 -US20060148796A1,7,CCc1cccc(C)c1C#N>>CCc1cccc(C)c1CN -US06008362,1,NNC(=S)Nc1ccccc1.O=C(CCCCl)c1ccccc1>>S=C(NN=C(CCCCl)c1ccccc1)Nc1ccccc1 -US20070287708A1,3,Cc1c(Nc2c(I)cncc2C#N)ccc2[nH]ccc12.OB(O)c1cc2ccccc2o1>>Cc1c(Nc2c(C#N)cncc2-c2cc3ccccc3o2)ccc2[nH]ccc12 -US06706725B1,6,CCC1(c2ccc(CCc3ccc(CO)c(CO)c3)s2)OCCO1>>CCC(=O)c1ccc(CCc2ccc(CO)c(CO)c2)s1 -US20110105566A1,3,CC(C)(C)OC(=O)Nc1cccc(Br)n1.CN(C)C=O>>CC(C)(C)OC(=O)Nc1cccc(C=O)n1 -US07935688B2,6,CCC(O)(C#Cc1ccc(C(CC)(CC)c2ccc(-c3cncc(CC(=O)OC)c3)c(C)c2)cc1C)CC>>CCC(O)(C#Cc1ccc(C(CC)(CC)c2ccc(-c3cncc(CC(=O)O)c3)c(C)c2)cc1C)CC -US20070249670A1,2,Nc1cc2ccccc2cc1C(=O)NC1(C(=O)O)CCCCC1.O=C=Nc1ccc(-c2ccccc2)cc1>>O=C(Nc1ccc(-c2ccccc2)cc1)Nc1cc2ccccc2cc1C(=O)NC1(C(=O)O)CCCCC1 -US08415381B2,1,Fc1cccc(CNc2cccc(-c3cc(F)ncc3Cl)n2)c1.N[C@@H]1CC[C@H](C(=O)O)C1>>O=C(O)[C@H]1CC[C@@H](Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1 -US20130237519A1,2,CC(C)(N)CO.C[C@H]1CCC[C@@H](C)N1CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(-c4ccc(C(=O)O)c(F)c4)ccn23)c1>>C[C@H]1CCC[C@@H](C)N1CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(-c4ccc(C(=O)NC(C)(C)CO)c(F)c4)ccn23)c1 -US20110059992A1,3,N#Cc1ccccc1[Zn+].O=C(Cl)c1ccc(F)c(Br)c1>>N#Cc1ccccc1C(=O)c1ccc(F)c(Br)c1 -US20080188521A1,7,Cc1cccc(-c2cc(=O)oc3cc(C(=O)O)ccc23)c1>>Cc1cccc(-c2cc(=O)oc3cc(CO)ccc23)c1 -US20130158075A1,2,COC(=O)CCCc1nnc(-c2ccc(N)cc2)s1.O=C=Nc1cccc(C(F)(F)F)c1>>COC(=O)CCCc1nnc(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)s1 -US20070179173A1,6,COc1ccc(-c2ccccc2)c2c1CCC(=O)N2Cc1ccc(-c2ccccc2)cc1>>O=C1CCc2c(O)ccc(-c3ccccc3)c2N1Cc1ccc(-c2ccccc2)cc1 -US20120277208A1,2,CN.COC(=O)c1nnc(-c2ccc(F)cn2)o1>>CNC(=O)c1nnc(-c2ccc(F)cn2)o1 -US06008213,6,CCOC(=O)CC1Cc2ccc(C(=O)NCCNc3ccccn3)cc2Cc2ccccc21>>O=C(O)CC1Cc2ccc(C(=O)NCCNc3ccccn3)cc2Cc2ccccc21 -US07842713B2,2,CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cc(C)sc2c1.Cc1ccc(N)nc1>>Cc1ccc(NC(=O)c2cc(Oc3ccc(S(C)(=O)=O)cc3)c3cc(C)sc3c2)nc1 -US05965763,2,NC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(Br)CBr>>O=C(CBr)NC(c1ccccc1)(c1ccccc1)c1ccccc1 -US05418146,2,COC(=O)[C@@H](N)Cc1ccccc1.O=C(O)C[C@H](NC(=O)c1ccccc1)C(=O)O>>COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)c1ccccc1 -US20130172360A1,6,CCOC(=O)c1cc(C#N)c(SC)nc1N>>CSc1nc(N)c(C(=O)O)cc1C#N -US20080319188A1,1,CCOC(=O)c1cc(Cl)ccn1.O=[N+]([O-])c1ccc(O)cc1F>>CCOC(=O)c1cc(Oc2ccc([N+](=O)[O-])c(F)c2)ccn1 -US20080227781A1,1,CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)C=O)cn1.CNC>>CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN(C)C)cn1 -US20020183309A1,3,CON(C)C(=O)c1ccc2oc(CCN3CCC[C@H]3C)cc2c1.Fc1cc(F)cc([Mg+])c1>>C[C@@H]1CCCN1CCc1cc2cc(C(=O)c3cc(F)cc(F)c3)ccc2o1 -US04137234,7,O=C(O)c1nccnc1O>>OCc1nccnc1O -US20080275022A1,6,COc1ccc2ncn(-c3cc(NC(=O)c4cccc(C(F)(F)F)c4)ccc3C)c(=O)c2c1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1cnc2ccc(O)cc2c1=O -US06441017B1,7,CC(C)(C)[Si](C)(C)Oc1cnc2cccc([N+](=O)[O-])c2c1>>CC(C)(C)[Si](C)(C)Oc1cnc2cccc(N)c2c1 -US20100249179A1,6,COC(=O)c1ccc2cccc(Nc3ccc(OC)cc3)c2c1>>COC(=O)c1ccc2cccc(Nc3ccc(O)cc3)c2c1 -US20100305109A1,2,CC(C)c1nc2ccccc2c(=O)n1N.O=C(Cl)CC12CC3CC(CC(Cl)(C3)C1)C2>>CC(C)c1nc2ccccc2c(=O)n1NC(=O)CC12CC3CC(CC(Cl)(C3)C1)C2 -US20150133446A1,1,CC(C)(C)[Si](C)(C)Oc1cc(OCc2cccc(OCc3ccccc3)c2)c2cc(-c3cn4nc(Br)sc4n3)oc2c1.C[O-]>>COc1nn2cc(-c3cc4c(OCc5cccc(OCc6ccccc6)c5)cc(O[Si](C)(C)C(C)(C)C)cc4o3)nc2s1 -US20100036118A1,1,Clc1ncccn1.Nc1ccc(Br)cc1F>>Fc1cc(Br)ccc1Nc1ncccn1 -US08802864B2,1,N#CCCl.O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(-c3ccc4occc4c3)cc2)C1>>N#CCn1nc(C[C@@H]2CCN(C(=O)C3CC3)C2)n(-c2ccc(-c3ccc4occc4c3)cc2)c1=O -US20050209217A1,2,CON(C)C(=O)[C@@H]1[C@@H](O)CCN1C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CON(C)C(=O)[C@@H]1[C@@H](OS(C)(=O)=O)CCN1C(=O)OC(C)(C)C -US20050176955A1,6,COC(=O)c1nc(N(C)S(C)(=O)=O)c2cccnc2c1O>>CN(c1nc(C(=O)O)c(O)c2ncccc12)S(C)(=O)=O -US04444775,6,CCOC(=O)C=CCCCCCc1cccc2cncn12>>O=C(O)C=CCCCCCc1cccc2cncn12 -US07125896B2,1,BrCC1CC1.OCCOc1ccc(Br)cc1>>Brc1ccc(OCCOCC2CC2)cc1 -US06329389B1,3,CCOC(=O)CC(=O)OCC.O=Cc1cc(Cl)ccc1[N+](=O)[O-]>>CCOC(=O)C(=Cc1cc(Cl)ccc1[N+](=O)[O-])C(=O)OCC -US04619927,1,O=C1CNCCN1.O=[N+]([O-])c1nccnc1Cl>>O=C1CN(c2nccnc2[N+](=O)[O-])CCN1 -US20100004238A1,6,CC(C)(C)OC(=O)N1CCc2c(Oc3ccc(Nc4ncnc5ccn(CCO)c45)cc3Cl)cccc21>>OCCn1ccc2ncnc(Nc3ccc(Oc4cccc5c4CCN5)c(Cl)c3)c21 -US20110263571A1,1,CC[C@@H]1COC(=O)N1.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(I)cc2)CC1>>CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C4CC4)cc3C)CC2)cc1 -US08680108B2,7,CC(=O)c1cc(Cl)c2cccnc2c1-c1ccccc1F>>CC(O)c1cc(Cl)c2cccnc2c1-c1ccccc1F -US05140018,8,O=C(OO)c1cccc(Cl)c1.c1ccc(CCN2Sc3ccccc3S2)cc1>>O=S1c2ccccc2SN1CCc1ccccc1 -US20140364433A1,2,C[C@@H]1CCCN[C@@H]1CNc1nc2cc(Cl)ccc2o1.Cc1ccc(-c2cncs2)c(C(=O)O)c1>>Cc1ccc(-c2cncs2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2nc3cc(Cl)ccc3o2)c1 -US07820707B2,6,CC(C)(C)OC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2>>O=C(O)Cn1nc(C(F)(F)F)c2c1CCCC2 -US07618978B2,1,CC[C@H](C)N.COC(=O)c1cc(Cl)nc(S(=O)(=O)C(C)C)c1>>CC[C@H](C)Nc1cc(C(=O)OC)cc(S(=O)(=O)C(C)C)n1 -US20050197338A1,2,CN=C=O.NC(=O)c1nn(-c2cccc(Br)c2)cc1N>>CNC(=O)Nc1cn(-c2cccc(Br)c2)nc1C(N)=O -US20070299092A1,1,CN.COc1cc2ncnc(NC3=CC(=O)C(Cl)=CC3=O)c2cc1OC>>CNC1=CC(=O)C(Nc2ncnc3cc(OC)c(OC)cc23)=CC1=O -US07482484B2,9,CCCCCCc1cc2c(cc1OCCCC(=O)O)C(=O)CC2.NO>>CCCCCCc1cc2c(cc1OCCCC(=O)O)C(=NO)CC2 -US05585358,2,CC(C)CC(N)C(N)=O.CCCC(CCC)C(=O)Cl>>CCCC(CCC)C(=O)NC(=O)[C@@H](N)CC(C)C -US07572809B2,1,CC(C)O.COCCOc1cc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2cc1OCC1COC(C)(C)O1>>COCCOc1cc2c(OC(C)C)nc(Nc3cc(C)[nH]n3)cc2cc1OCC1COC(C)(C)O1 -US20100093811A1,2,COC(=O)[C@@H](N)CCCCOCc1ccccc1.COC(=O)c1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1ccc(S(=O)(=O)N[C@@H](CCCCOCc2ccccc2)C(=O)OC)cc1 -US20010029239A1,6,COC=C(Oc1cccc(OC(=COC)C(=O)OC)c1C(=O)OC(C)(C)C)C(=O)OC>>COC=C(Oc1cccc(OC(=COC)C(=O)OC)c1C(=O)O)C(=O)OC -US05411973,3,C#Cc1ccc(C(=O)c2ccccc2)cc1.CC(=O)C(F)(F)F>>CC(O)(C#Cc1ccc(C(=O)c2ccccc2)cc1)C(F)(F)F -US05985869,6,O=C(Nc1ccc(C(=O)N2CCCCc3ccccc32)cc1)c1ccccc1OCCCCCCN1C(=O)c2ccccc2C1=O>>NCCCCCCOc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCCc3ccccc32)cc1 -US20150252047A1,1,CC(C)Cc1[nH]c2ncnc(Cl)c2c1C(C)C.COc1cc2[nH]ncc2cc1N>>COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c(CC(C)C)c(C(C)C)c12 -US06022492,3,Brc1cnc(Br)nc1.CCCCCCCCCCCCOc1ccc(B(O)O)cn1>>CCCCCCCCCCCCOc1ccc(-c2ncc(Br)cn2)cn1 -US08846910B2,7,COC(=O)/C=C/c1ccc(-c2cc(F)cc(F)c2)cc1>>COC(=O)CCc1ccc(-c2cc(F)cc(F)c2)cc1 -US20090149463A1,2,Cc1c(C(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCc2ccccc2)cc1.NN1CCCCC1>>Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCc2ccccc2)cc1 -US20120225910A1,1,BrCc1ccccc1.Nc1ccc(C(=O)O)cn1>>Nc1ccc(C(=O)OCc2ccccc2)cn1 -US20110086854A1,6,CCOC(=O)CC1CCN(C(=O)N2C[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)CC1>>CC(C)(C)C[C@@H]1CN(C(=O)N2CCC(CC(=O)O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20030092140A1,3,CCC(=O)n1c(=O)oc2ccccc21.O=C1CCCCC1>>CC(C(=O)n1c(=O)oc2ccccc21)C1(O)CCCCC1 -US20100204196A1,7,COc1cc(N2CCN(C(C)C)CC2)c(F)cc1[N+](=O)[O-]>>COc1cc(N2CCN(C(C)C)CC2)c(F)cc1N -US20010034352A1,6,CC(C)(C)OC(=O)NC1CCN(CC(F)Cc2coc3ccccc23)CC1>>NC1CCN(CC(F)Cc2coc3ccccc23)CC1 -US20040254179A1,1,Cc1nc(C#Cc2cccc(C(F)(F)F)c2)c[nH]1.Fc1cncc(F)c1>>Cc1nc(C#Cc2cccc(C(F)(F)F)c2)cn1-c1cncc(F)c1 -US20100324010A1,6,CC(C)(C)OC(=O)N1CC2CCCCC2C(NC(=O)C(F)(F)F)C1>>CC(C)(C)OC(=O)N1CC(N)C2CCCCC2C1 -US20090264415A2,1,CC(Cl)C(=O)N1CCN(c2nc(N)nc3ccc(-c4ccc(F)cc4)nc23)CC1.Oc1ccccc1>>CC(Oc1ccccc1)C(=O)N1CCN(c2nc(N)nc3ccc(-c4ccc(F)cc4)nc23)CC1 -US20130217664A1,3,CCc1cc(Br)ccc1N.Cn1cc(B(O)O)cn1>>CCc1cc(-c2cnn(C)c2)ccc1N -US06218376B1,1,Cn1cc(C2c3ccc(Cl)cc3C=Cc3sc(Cl)nc32)c(=O)[nH]c1=O.NCc1ccccc1>>Cn1cc(C2c3ccc(Cl)cc3C=Cc3sc(NCc4ccccc4)nc32)c(=O)[nH]c1=O -US20090099181A1,3,C#Cc1ccc(NC(=O)c2cccs2)cc1.C[S@@](=O)(=NC(=O)c1cncc(Br)c1)c1ccccc1>>C[S@@](=O)(=NC(=O)c1cncc(C#Cc2ccc(NC(=O)c3cccs3)cc2)c1)c1ccccc1 -US20150065519A1,3,O=S(=O)(Nc1ccc(-c2csc(Br)n2)c(Cl)c1)C(F)(F)F.OB(O)c1cccc2[nH]ccc12>>O=S(=O)(Nc1ccc(-c2csc(-c3cccc4[nH]ccc34)n2)c(Cl)c1)C(F)(F)F -US05919936,2,Nc1ccc2[nH]cc(C3CCN(CCc4ccccc4)CC3)c2n1.O=C(Cl)c1ccc(F)cc1>>O=C(Nc1ccc2[nH]cc(C3CCN(CCc4ccccc4)CC3)c2n1)c1ccc(F)cc1 -US07442791B2,6,COC(=O)[C@@H]1CC[C@@H](N(C)C(=O)Oc2ccc(Cl)cc2)CC1>>CN(C(=O)Oc1ccc(Cl)cc1)[C@@H]1CC[C@@H](C(=O)O)CC1 -US09072734B2,9,O=c1ccc2c([C@@H](O)CBr)ccc(OCc3ccccc3)c2[nH]1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC[C@H](O)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12 -US20120165317A1,6,CCOC(=O)C1=Cc2ccc(C(F)(F)C(F)(F)F)cc2N=C(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)C1=Nc2cc(C(F)(F)C(F)(F)F)ccc2C=C(C(=O)O)C1 -US06693101B2,1,C=O.CCOC(=O)CC(C=CCCCCc1cccc(NCc2ccc(OC)cc2)n1)c1cncnc1>>CCOC(=O)CC(C=CCCCCc1cccc(N(C)Cc2ccc(OC)cc2)n1)c1cncnc1 -US08003649B2,1,CC(C)(C)OC(=O)Nc1ccc(C=O)cc1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>CC(C)(C)OC(=O)Nc1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US06800778B1,7,CCOC(=O)C(C)(C)C(=O)c1ccccc1Cl>>CCOC(=O)C(C)(C)C(O)c1ccccc1Cl -US20130289033A1,3,N#Cc1ccc(B(O)O)cc1.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccccc1I>>N#Cc1ccc(-c2ccccc2C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 -US05843957,9,BrC(Br)(Br)Br.CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(C#CCO)c2)c2cccnc21>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(C#CCBr)c2)c2cccnc21 -US20140155391A1,7,CSc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1[N+](=O)[O-]>>CSc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1N -US08691810B2,6,COCOC1(c2ncc(-c3c(Cl)cnc4[nH]c(-c5ccc(OCC6CCCO6)cc5)cc34)s2)CCC1>>OC1(c2ncc(-c3c(Cl)cnc4[nH]c(-c5ccc(OCC6CCCO6)cc5)cc34)s2)CCC1 -US06630504B2,5,CSc1ccc(Oc2ccccc2C2CCCN2)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CSc1ccc(Oc2ccccc2C2CCCN2C(=O)C(F)(F)F)cc1 -US20060241172A1,3,COc1cccc(F)c1B(O)O.Cc1ccccc1Br>>COc1cccc(F)c1-c1ccccc1C -US07842685B2,3,C[Si](C)(C)C[Mg+].O=C(c1ccc2nc(-c3ccc(C4OCCCO4)cc3F)sc2n1)C1CCC1>>C[Si](C)(C)CC(O)(c1ccc2nc(-c3ccc(C4OCCCO4)cc3F)sc2n1)C1CCC1 -US20110190227A1,2,CC(C)(C)C(=O)Cl.COC(=O)Cc1cc(Cl)cc(Oc2ccc(N)cc2CSC(C)C)c1>>COC(=O)Cc1cc(Cl)cc(Oc2ccc(NC(=O)C(C)(C)C)cc2CSC(C)C)c1 -US20090298836A1,4,CNc1cc(-c2nnc(N(C[C@H](Cc3ccc(C(F)(F)F)cc3)NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)s2)ccc1N.O=C(n1ccnc1)n1ccnc1>>Cn1c(=O)[nH]c2ccc(-c3nnc(N(C[C@H](Cc4ccc(C(F)(F)F)cc4)NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)s3)cc21 -US20120028973A1,7,COC(=O)c1ccc(/C=C/c2ccc(OC(F)(F)F)cc2)cc1>>OCc1ccc(/C=C/c2ccc(OC(F)(F)F)cc2)cc1 -US09115093B2,2,CS(=O)(=O)Cl.N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)(F)F)c3)C3=C2C(=O)CCC3)c(Cl)c1>>CS(=O)(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1Cl -US08822471B2,2,CC(C)(C)c1noc(N2CCC(NC3CC3)CC2)n1.O=C(O)c1ccc(-c2cnco2)c(F)c1>>CC(C)(C)c1noc(N2CCC(N(C(=O)c3ccc(-c4cnco4)c(F)c3)C3CC3)CC2)n1 -US20140024776A1,1,C=CCBr.OCC12CN3C(c4ccccc4)N(C1)C(c1ccccc1)N(C2)C3c1ccccc1>>C=CCOCC12CN3C(c4ccccc4)N(C1)C(c1ccccc1)N(C2)C3c1ccccc1 -US20070197512A1,7,CC(C)C1Oc2ccc(Cl)cc2NC1=O>>CC(C)C1CNc2cc(Cl)ccc2O1 -US06071966,2,CNC1(C)CC(C)(C)CC(C)(C)C1.COC(=O)Cl>>COC(=O)N(C)C1(C)CC(C)(C)CC(C)(C)C1 -US20110009454A1,7,CCCC=Cc1cccc(C#N)c1>>CCCCCc1cccc(C#N)c1 -US20140142114A1,2,FC(F)(F)c1ccc2c(c1)CC(CN1CCNCC1)O2.N#Cc1ccc(NC2CCC(OCC(=O)O)CC2)cc1C(F)(F)F>>N#Cc1ccc(NC2CCC(OCC(=O)N3CCN(CC4Cc5cc(C(F)(F)F)ccc5O4)CC3)CC2)cc1C(F)(F)F -US20030220524A1,1,CS(=O)(=O)c1ccccc1Cl.SCc1ccccc1>>CS(=O)(=O)c1ccccc1SCc1ccccc1 -US07557127B2,6,CCOC(=O)/C=C/c1ccc(N(C(=O)OC(C)(C)C)[C@@H]2CCN(Cc3ccccc3)C2)nc1>>CCOC(=O)/C=C/c1ccc(N(C(=O)OC(C)(C)C)[C@@H]2CCNC2)nc1 -US20070249603A1,1,CNC1CCNCC1.O=S(=O)(c1ccccc1)c1cnc2c(F)cccc2c1>>CNC1CCN(c2cccc3cc(S(=O)(=O)c4ccccc4)cnc23)CC1 -US04153607,4,NC(=S)c1sc(-c2ccccc2)nc1N>>Nc1snc2nc(-c3ccccc3)sc12 -US04552585,2,CO.Cc1ccccc1C(=O)O>>COC(=O)c1ccccc1C -US07351841B2,1,CC(C)(C)c1ccc(-c2scc(C=O)c2O)cc1.NNC(=S)Nc1ccc(C(=O)O)cc1>>CC(C)(C)c1ccc(-c2scc(C=NNC(=S)Nc3ccc(C(=O)O)cc3)c2O)cc1 -US20140249139A1,3,CC(=O)N1CCN(C(=O)c2cc(-c3ncnc4ccc(Br)cc34)cc(C(F)(F)F)c2)CC1.COc1ccc(B(O)O)cn1>>COc1ccc(-c2ccc3ncnc(-c4cc(C(=O)N5CCN(C(C)=O)CC5)cc(C(F)(F)F)c4)c3c2)cn1 -US04728646,1,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3c(SCc4cccc(F)c4)ncnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3c(SCc4cccc(F)c4)ncnc23)CC1 -US20110245227A1,6,CSc1ccc(-n2ccc(OC3CCN(C(=O)OCc4ccccc4)CC3)cc2=O)cc1>>CSc1ccc(-n2ccc(OC3CCNCC3)cc2=O)cc1 -US20130225569A1,3,CN1CCN(C(=O)c2cccc(B3OC(C)(C)C(C)(C)O3)c2)CC1.COc1cc(-c2cc3nccc(Cl)c3o2)cc(OC)c1OC>>COc1cc(-c2cc3nccc(-c4cccc(C(=O)N5CCN(C)CC5)c4)c3o2)cc(OC)c1OC -US20090298823A1,1,Clc1nc(Cl)c2cc[nH]c2n1.NCCCN1CCOCC1>>Clc1nc(NCCCN2CCOCC2)c2cc[nH]c2n1 -US07435744B2,1,O=C(CCl)Nc1ccc2c(c1)OCC(=O)N2.c1ccc(COC2CCNCC2)cc1>>O=C(CN1CCC(OCc2ccccc2)CC1)Nc1ccc2c(c1)OCC(=O)N2 -US20040006141A1,6,COCOCc1cccc(-c2ccc(C(=O)OC)cc2)c1>>COCOCc1cccc(-c2ccc(C(=O)O)cc2)c1 -US20110237639A1,7,N#CCc1ccc([N+](=O)[O-])c(Cl)c1Br>>N#CCc1ccc(N)c(Cl)c1Br -US20110039852A1,3,CCN(Cc1cc(C(F)(F)F)ccc1B1OC(C)(C)C(C)(C)O1)C(=O)C1CC1.COC(=O)Cc1cc(OS(=O)(=O)C(F)(F)F)cc(C(F)(F)F)c1>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)cc(C(F)(F)F)c1)C(=O)C1CC1 -US08470816B2,2,CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(C(=O)C2CCNCC2)C[C@H]1c1ccc(Cl)c(Cl)c1.O=C(O)C1(O)CC1>>CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(C(=O)C2CCN(C(=O)C3(O)CC3)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US07582626B2,1,COC(=O)[C@@H]1CCC[C@@H]1N.O=Cc1ccc(F)cc1>>COC(=O)[C@@H]1CCC[C@@H]1NCc1ccc(F)cc1 -US07192918B2,10,Cc1ccc(-c2ccccn2)cc1.O=C1CCC(=O)N1Br>>BrCc1ccc(-c2ccccn2)cc1 -US07405299B2,3,Brc1c(-c2ccccn2)nn2c1CCC2.OB(O)c1ccc2[nH]ccc2c1>>c1ccc(-c2nn3c(c2-c2ccc4[nH]ccc4c2)CCC3)nc1 -US20140378487A1,7,O=Cc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1Cl>>OCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1Cl -US08119666B2,3,CCc1ccnc(Br)c1.C[Si](C)(C)CCN1C(=O)CN(c2ccc(CI)cc2OCc2ccccc2)S1(=O)=O>>CCc1ccnc(Cc2ccc(N3CC(=O)N(CC[Si](C)(C)C)S3(=O)=O)c(OCc3ccccc3)c2)c1 -US20130146851A1,6,CCCC(C)n1ccc2cc(OCc3ccccc3)ccc21>>CCCC(C)n1ccc2cc(O)ccc21 -US05688798,1,Cc1ncc(CCl)c(N)n1.c1ccc(COc2ccc3c(c2)CNCC3)cc1>>Cc1ncc(CN2CCc3ccc(OCc4ccccc4)cc3C2)c(N)n1 -US20100273781A1,6,COC(=O)c1cnc(C)c(F)c1>>Cc1ncc(C(=O)O)cc1F -US20150239873A1,6,CCOC(=O)CC(CN1CCCC(c2cccc(C(F)(F)F)c2)C1)C(F)(F)F>>O=C(O)CC(CN1CCCC(c2cccc(C(F)(F)F)c2)C1)C(F)(F)F -US20100256357A1,1,C[C@H]1CNC[C@@H](C)O1.NS(=O)(=O)c1ccc(-n2nc(CCl)nc2Cc2ccccc2)c(F)c1>>C[C@H]1CN(Cc2nc(Cc3ccccc3)n(-c3ccc(S(N)(=O)=O)cc3F)n2)C[C@@H](C)O1 -US20110034507A1,6,COC(=O)[C@H]1CCN(C(=O)n2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc32)C1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2c(ccn2C(=O)N2CC[C@H](C(=O)O)C2)c1 -US20130030012A1,1,CN1CCCn2c1cc(Cl)nc2=O.OCCc1ccc(Oc2ccc(F)c(F)c2)nc1>>CN1CCCn2c1cc(OCCc1ccc(Oc3ccc(F)c(F)c3)nc1)nc2=O -US04483989,6,COc1ccc2[nH]c3c(C)ccc(C)c3c2c1>>Cc1ccc(C)c2c1[nH]c1ccc(O)cc12 -US20130274260A1,3,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CCl)c1.OB(O)c1ccc(F)cc1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccc(F)cc2)c1 -US20120149702A1,6,c1ccc(COc2cccc3cc[nH]c23)cc1>>Oc1cccc2cc[nH]c12 -US04791055,1,NCCNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>Nc1ncnc2c1nc(NCCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])n2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O -US20130172384A1,3,Cn1nc(-c2ccc(Br)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O.OB(O)c1ccc2[nH]ccc2c1>>Cn1nc(-c2ccc(-c3ccc4[nH]ccc4c3)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O -US20140200207A1,7,CC1(O)CCC(=O)CC1>>CC1(O)CCC(O)CC1 -US20130345245A1,6,Cn1c(-c2nc(N)ncc2C#Cc2cccc(O)c2)cc2c1CCN(C(=O)OC(C)(C)C)C2=O>>Cn1c(-c2nc(N)ncc2C#Cc2cccc(O)c2)cc2c1CCNC2=O -US20050148624A1,2,CC(=O)OC(C)=O.CCC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(N)(=O)=O)cc1>>CCC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(=O)(=O)NC(C)=O)cc1 -US20150282482A1,3,COC(=O)c1cc2c(Br)cccc2s1.OB(O)c1cccs1>>COC(=O)c1cc2c(-c3cccs3)cccc2s1 -US20100204233A1,3,CCOP(=O)(Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)OCC.O=Cc1ccccc1Cl>>Clc1ccccc1C=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US08426422B2,6,CCOC(=O)c1ccc(N2CCN(CC=C(c3ccccc3)c3ccccc3)CC2)cc1>>O=C(O)c1ccc(N2CCN(CC=C(c3ccccc3)c3ccccc3)CC2)cc1 -US07964622B2,4,CCCc1cc(C(N)=S)ccc1O.O=C1CCCCC1Cl>>CCCc1cc(-c2nc3c(s2)CCCC3)ccc1O -US08039493B2,1,CC(C)S(=O)(=O)NCc1cccc(-c2cccc(S(C)(=O)=O)c2)c1.Fc1ccc(CBr)cc1>>CC(C)S(=O)(=O)N(Cc1ccc(F)cc1)Cc1cccc(-c2cccc(S(C)(=O)=O)c2)c1 -US06376707B1,6,CCOC(=O)COc1ccc(CCN[C@@H](C)[C@H](O)c2ccc(O)cc2)cc1>>C[C@H](NCCc1ccc(OCC(=O)O)cc1)[C@H](O)c1ccc(O)cc1 -US06300352B1,3,C[C@H](Oc1ccc(B(O)O)cc1)[C@H](O)CCc1cccnc1.N#Cc1ccc(F)c(Br)c1>>C[C@H](Oc1ccc(-c2cc(C#N)ccc2F)cc1)[C@H](O)CCc1cccnc1 -US07560558B2,7,CCOC(=O)CCc1cc2nccc(Oc3cc4ccccc4nc3C)c2cc1OC>>COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1CCCO -US20150158826A1,2,Nc1cc(F)c(F)c(C(=O)c2ccc3ncc(N4CCOCC4)nc3c2)c1F.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C(Nc1cc(F)c(F)c(C(=O)c2ccc3ncc(N4CCOCC4)nc3c2)c1F)c1cccc(C(F)(F)F)c1 -US09108939B2,1,CC(=O)Nc1ccc(C(=O)C2CCNCC2)cc1.OC(c1ccc(CBr)cc1)(C(F)(F)F)C(F)(F)F>>CC(=O)Nc1ccc(C(=O)C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1 -US20150152047A1,6,O=C(OCc1ccccc1)N1CCC[C@H](NS(=O)(=O)CCN2C(=O)c3ccccc3C2=O)C1>>NCCS(=O)(=O)N[C@H]1CCCN(C(=O)OCc2ccccc2)C1 -US05654435,2,CC(=O)OC(C)=O.NCC1CN(c2cc(F)c(-c3cccnc3)c(F)c2)C(=O)O1>>CC(=O)NCC1CN(c2cc(F)c(-c3cccnc3)c(F)c2)C(=O)O1 -US20070149563A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=C(N[C@H]1CN2CCC1CC2)c1ccc(Br)s1>>O=C(N[C@H]1CN2CCC1CC2)c1ccc(-c2ccccn2)s1 -US05998433,3,O=Cc1ccc(S(=O)(=O)N2CCc3ccoc3C2)cc1.[Mg+]c1ccccc1>>O=S(=O)(c1ccc(C(O)c2ccccc2)cc1)N1CCc2ccoc2C1 -US05972951,3,Cc1nc(-c2ccc(Br)cc2)no1.O=C(O)c1ccc(B(O)O)cc1>>Cc1nc(-c2ccc(-c3ccc(C(=O)O)cc3)cc2)no1 -US07943645B2,2,CC(C)(C)OC(=O)N1CCCCC1CC(=O)O.NCC(=O)c1ccccc1>>CC(C)(C)OC(=O)N1CCCCC1CC(=O)NCC(=O)c1ccccc1 -US07186715B2,1,CC(C)(C)OC(=O)N1CCN(c2ccccc2O)CC1.CN1CCC(O)C1>>CN1CCC(Oc2ccccc2N2CCN(C(=O)OC(C)(C)C)CC2)C1 -US05772990,8,CCNc1cc(Cl)nc(N)n1.O=C(OO)c1cccc(Cl)c1>>CCNc1cc(Cl)nc(N)[n+]1[O-] -US20090149501A1,2,CS(=O)(=O)Cl.OCCN1CCCC1>>CS(=O)(=O)OCCN1CCCC1 -US20100256097A1,7,CC(=O)c1ccc(-c2cc(C(N)=O)c([N+](=O)[O-])s2)cc1>>CC(O)c1ccc(-c2cc(C(N)=O)c([N+](=O)[O-])s2)cc1 -US05792763,9,CC(=O)CCCN(C)C.NO>>CC(CCCN(C)C)=NO -US07309793B2,1,CI.COC(OC)[C@@]1(C)Oc2ccc([N+](=O)[O-])cc2[C@H](n2c(=NC#N)[nH]c3ccccc32)[C@H]1O>>COC(OC)[C@@]1(C)Oc2ccc([N+](=O)[O-])cc2[C@H](n2c(=NC#N)n(C)c3ccccc32)[C@H]1O -US07964616B2,1,C[C@H]1CCC[C@@](O)(CNC(=O)c2c(Cl)ccc3nc(Cl)ccc23)C1.OC1CCNCC1>>C[C@H]1CCC[C@@](O)(CNC(=O)c2c(Cl)ccc3nc(N4CCC(O)CC4)ccc23)C1 -US20090233929A1,3,O=C(c1ccccc1)c1cn(-c2cccc(Br)c2)cn1.OB(O)c1ccccc1>>O=C(c1ccccc1)c1cn(-c2cccc(-c3ccccc3)c2)cn1 -US20060194780A1,1,CCOC(=O)N1C2CCC1CC(C(=O)O)C2.OC1C=CCCC1>>CCOC(=O)N1C2CCC1CC(C(=O)OC1C=CCCC1)C2 -US03939166,1,CC1CCCCC1N.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c2[nH]c(C(F)(F)F)nc12>>CC1CCCCC1Nc1c(C(F)(F)F)cc([N+](=O)[O-])c2nc(C(F)(F)F)[nH]c12 -US04268511,2,CC(=O)Nn1c(=O)[nH]c2ccccc2c1=O.CC(=O)OC(C)=O>>CC(=O)N(C(C)=O)n1c(=O)[nH]c2ccccc2c1=O -US20120022045A1,10,C1=COC(COCc2ccccc2)CC1.O>>OC1CCC(COCc2ccccc2)OC1 -US20150005232A1,3,COc1cc(C)c(B(O)O)cn1.FC(F)(F)c1cc(Br)c2cn[nH]c2c1>>COc1cc(C)c(-c2cc(C(F)(F)F)cc3[nH]ncc23)cn1 -US20050090508A1,6,CN(CCCOc1cc(F)c(-c2c(Cl)nc3ncnn3c2C2CCCCCC2)c(F)c1)C(=O)OC(C)(C)C>>CNCCCOc1cc(F)c(-c2c(Cl)nc3ncnn3c2C2CCCCCC2)c(F)c1 -US03991087,6,CCCCCC(CCCC(CCCCCCC(=O)O)(C(C)=O)c1ccccc1)OCc1ccccc1>>CCCCCC(O)CCCC(CCCCCCC(=O)O)(C(C)=O)c1ccccc1 -US20120289549A1,8,O=C1N(c2ccc(OCC(F)(F)F)cc2)CC2C[C@H](O)CN12>>O=C1C[C@H]2CN(c3ccc(OCC(F)(F)F)cc3)C(=O)N2C1 -US08927587B2,4,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O.CC(C)(C)c1ccc(N)c(N)c1>>CC(C)(C)OC(=O)N[C@@H](CO)c1nc2cc(C(C)(C)C)ccc2[nH]1 -US04425333,2,CCOC(=O)CN.O=C(SCCC(=O)N1[C@H](C(=O)O)CS[C@@H]1c1ccccc1O)c1ccccc1>>CCOC(=O)CNC(=O)[C@@H]1CS[C@H](c2ccccc2O)N1C(=O)CCSC(=O)c1ccccc1 -US08088790B2,9,CCOc1nc2c(Cl)nc3ccccc3c2[nH]1.N>>CCOc1nc2c(N)nc3ccccc3c2[nH]1 -US04701548,2,O=C(O)CCS.OCCCc1ccccc1>>O=C(CCS)OCCCc1ccccc1 -US20140329863A1,1,CNC.Fc1ccc(Br)cn1>>CN(C)c1ccc(Br)cn1 -US07799787B2,1,CC(C)CCNC(=O)c1ccc(Cl)nn1.FC(F)(F)c1cccc(OC2CCNCC2)c1>>CC(C)CCNC(=O)c1ccc(N2CCC(Oc3cccc(C(F)(F)F)c3)CC2)nn1 -US08034812B2,1,Cc1cc(C(=O)Nc2cc(O)ccc2F)n(C)n1.O=C(CC1CC1)Nc1cn2nc(I)ccc2n1>>Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)CC5CC5)cn4n3)ccc2F)n(C)n1 -US07745479B2,1,CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1.OB(O)c1cccc(F)c1>>CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3-c2cccc(F)c2)CC1 -US07977512B2,7,CCCN(CCC)CCCCC(N)Cc1ccc(CN=Cc2ncc[nH]2)cc1>>CCCN(CCC)CCCCC(N)Cc1ccc(CNCc2ncc[nH]2)cc1 -US20020032187A1,7,Cc1ccc([N+](=O)[O-])c(N)n1>>Cc1ccc(N)c(N)n1 -US07674811B2,2,C#CCN.Cc1nn(-c2ccc(Sc3cccc(C4(C(=O)O)CCOCC4)c3)cc2)c(=O)[nH]1>>C#CCNC(=O)C1(c2cccc(Sc3ccc(-n4nc(C)[nH]c4=O)cc3)c2)CCOCC1 -US05739083,1,CCCCBr.CSc1cc(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n[nH]1>>CCCCn1nc(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1SC -US05910506,9,CC(C)c1nc(CCl)n(C)c1Sc1cc(Cl)cc(Cl)c1.[N-]=[N+]=[N-]>>CC(C)c1nc(CN=[N+]=[N-])n(C)c1Sc1cc(Cl)cc(Cl)c1 -US20090118284A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1csc(N2CCNCC2)n1>>CC(C)(C)OC(=O)N1CCN(c2nccs2)CC1 -US20050209274A1,1,CC(=O)c1ccc2[nH]c(=O)sc2c1.CCCI>>CCCn1c(=O)sc2cc(C(C)=O)ccc21 -US04182897,1,O=C(O)C=Cc1ccc([N+](=O)[O-])cc1.Oc1ccccc1>>O=C(C=Cc1ccc([N+](=O)[O-])cc1)Oc1ccccc1 -US20090264428A1,9,Cc1cccc(-c2c(F)cccc2[C@H](OCCN=[N+]=[N-])[C@H]2CN(C(=O)OC(C)(C)C)CCO2)c1>>Cc1cccc(-c2c(F)cccc2[C@H](OCCN)[C@H]2CN(C(=O)OC(C)(C)C)CCO2)c1 -US20060142297A1,2,CC(C)Oc1cc(OCCN2CCNCC2)cc2ncnc(Nc3c(Cl)cnc4c3OCO4)c12.CN(C)CC(=O)Cl>>CC(C)Oc1cc(OCCN2CCN(C(=O)CN(C)C)CC2)cc2ncnc(Nc3c(Cl)cnc4c3OCO4)c12 -US20070191289A1,3,C#C[Si](C)(C)C.CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3cccc(Br)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C>>CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3cccc(C#C[Si](C)(C)C)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C -US20030171396A1,6,CCCOc1ccc(Cn2c(C)nc3c(C)cc(C(=O)OC)nc32)c(Cl)c1>>CCCOc1ccc(Cn2c(C)nc3c(C)cc(C(=O)O)nc32)c(Cl)c1 -US20140275071A1,1,OCCCBr.Oc1cccc(OC(F)(F)F)c1>>OCCCOc1cccc(OC(F)(F)F)c1 -US20090215857A1,6,CC(C)(C)OC(=O)N1CC[C@H](OCc2ccccc2-c2ccc(F)cc2F)C1>>Fc1ccc(-c2ccccc2CO[C@H]2CCNC2)c(F)c1 -US04231787,1,CC(CO)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1.CI>>COCC(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1 -US07067534B1,1,Clc1ccc2cc[nH]c2c1.Ic1ccccc1>>Clc1ccc2ccn(-c3ccccc3)c2c1 -US20120065224A1,1,CC(=O)CCc1cccc(F)c1.NNc1cc[nH]c(=O)c1>>CC(CCc1cccc(F)c1)=NNc1cc[nH]c(=O)c1 -US20030225131A1,6,CC(C)(C)OC(=O)N1CCCCC1CCNc1nccc2oc(Cc3cc(Cl)ccc3-n3cncn3)nc12>>Clc1ccc(-n2cncn2)c(Cc2nc3c(NCCC4CCCCN4)nccc3o2)c1 -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc[nH]n3)cc2c1.OB(O)c1cccc(C(F)(F)F)c1>>COc1ccc2c(-c3cccc(C(F)(F)F)c3)nc(Nc3cc[nH]n3)cc2c1 -US20140275092A1,6,CCc1c(COC)[nH]c2c(C#N)c(C)nn2c1=O>>CCc1c(CO)[nH]c2c(C#N)c(C)nn2c1=O -US07528136B2,2,N#Cc1ccccc1N1CCN(C(=O)C2CC(N)CN2Cc2ccccc2)CC1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>N#Cc1ccccc1N1CCN(C(=O)[C@@H]2C[C@H](NC(=O)c3cc(Cl)cc(Cl)c3)CN2Cc2ccccc2)CC1 -US20110207729A1,7,COC(=O)c1ccc(OCC(COC(=O)c2ccccc2)C(C)C)cc1>>COC(=O)c1ccc(OCC(CO)C(C)C)cc1 -US07928231B2,6,CC(=O)n1ncc2sc(-c3ccccc3)cc21>>c1ccc(-c2cc3[nH]ncc3s2)cc1 -US08153652B2,3,C=CC(=O)N(C)Cc1cn(Cc2ccccc2)c2ccccc12.O=C1CCc2cc(Br)cnc2N1>>CN(Cc1cn(Cc2ccccc2)c2ccccc12)C(=O)/C=C/c1cnc2c(c1)CCC(=O)N2 -US06114365,1,CC(C)c1cnc(NC(=O)Cc2csc(NC(=O)CCl)n2)s1.CNC>>CC(C)c1cnc(NC(=O)Cc2csc(NC(=O)CN(C)C)n2)s1 -US20060106037A1,7,CC(=O)C(CCCc1ccccc1)n1cnc2c(=O)[nH]c(Cc3ccc(OC(F)F)c([N+](=O)[O-])c3)nc21>>CC(=O)C(CCCc1ccccc1)n1cnc2c(=O)[nH]c(Cc3ccc(OC(F)F)c(N)c3)nc21 -US20100010053A1,1,CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)OC(C)(C)C)c[nH]c34)no2)cc1Cl.CI>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)OC(C)(C)C)cn(C)c34)no2)cc1Cl -US07968540B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1cccc([N+](=O)[O-])c1N>>Cc1ccc(S(=O)(=O)Nc2cccc([N+](=O)[O-])c2N)cc1 -US20090054411A1,1,CC(C)(C)OC(=O)N1CCCNCC1.CCI>>CCN1CCCN(C(=O)OC(C)(C)C)CC1 -US20110201640A1,3,CCCC[Sn](CCCC)(CCCC)c1ccco1.CCCc1nc2cc(Br)cc(C)c2[nH]1>>CCCc1nc2cc(-c3ccco3)cc(C)c2[nH]1 -US20130310333A1,6,CC(C)N(CCCCN1C(=O)c2ccccc2C1=O)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C2OC(C)(C)O[C@@H]21>>CC(C)N(CCCCN)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21 -US20150087585A1,1,C1CNCC(c2nnc3n2CCC3)C1.Nc1nc(Cl)ccc1[N+](=O)[O-]>>Nc1nc(N2CCCC(c3nnc4n3CCC4)C2)ccc1[N+](=O)[O-] -US07465806B2,6,COC(=O)CCc1c(C)c(C(=O)NC2CCN(C(C)C)CC2)n(Cc2cc(-c3ccc(Cl)s3)on2)c1C>>Cc1c(CCC(=O)O)c(C)n(Cc2cc(-c3ccc(Cl)s3)on2)c1C(=O)NC1CCN(C(C)C)CC1 -US20090227530A1,7,CC(C)(C)OC(=O)NCCC#Cc1ccc(C#N)cc1>>CC(C)(C)OC(=O)NCCCCc1ccc(C#N)cc1 -US20070270421A1,7,CN1CC(N2CCC(N(C)C(=O)Nc3cc(Oc4ccc([N+](=O)[O-])cc4F)ncn3)CC2)C1>>CN1CC(N2CCC(N(C)C(=O)Nc3cc(Oc4ccc(N)cc4F)ncn3)CC2)C1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](C(C)C)NC1=O.O=C(O)[C@@H]1C[C@H]1c1ccc(F)c(F)c1>>CC(C)C[C@H]1C(=O)N[C@@H](C(C)C)CN1C(=O)[C@@H]1C[C@H]1c1ccc(F)c(F)c1 -US20120122843A1,1,ClCc1ccc(Cl)nc1Cl.NC[C@H](O)c1ccccc1>>O[C@@H](CNCc1ccc(Cl)nc1Cl)c1ccccc1 -US20050148627A1,6,CCOC(=O)C1=Cc2cc(Cl)c(OC)cc2OC1C(F)(F)F>>COc1cc2c(cc1Cl)C=C(C(=O)O)C(C(F)(F)F)O2 -US08518968B2,1,NNC(=O)c1cc2ccccc2cc1O.O=C/C=C/c1ccc([N+](=O)[O-])o1>>O=C(N/N=C/C=C/c1ccc([N+](=O)[O-])o1)c1cc2ccccc2cc1O -US07863291B2,7,O=[N+]([O-])c1ccc(OC(F)F)nc1>>Nc1ccc(OC(F)F)nc1 -US20100222346A1,1,Cc1cc(Cl)c2ccccc2n1.NCc1cccc(Cl)c1Cl>>Cc1cc(NCc2cccc(Cl)c2Cl)c2ccccc2n1 -US06525054B1,1,CC(C)(C)[O-].O=[N+]([O-])c1c(Cl)c(Cl)cc2nc(Cl)c(Cl)nc12>>CC(C)(C)Oc1nc2c([N+](=O)[O-])c(Cl)c(Cl)cc2nc1Cl -US20110112121A1,1,CCOC(=O)CC(=O)CCl.OCc1ccccc1>>CCOC(=O)CC(=O)COCc1ccccc1 -US09156827B2,3,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1.O=Cc1c[nH]c2ncccc12>>CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2O/C(=C\c2c[nH]c4ncccc24)C3=O)CC1 -US08344135B2,2,Cc1ccc(N)cc1Oc1ccc2nc(NC(=O)C3CC3)nn2c1.N#CC1(c2cccc(C(=O)Cl)c2)CC1>>Cc1ccc(NC(=O)c2cccc(C3(C#N)CC3)c2)cc1Oc1ccc2nc(NC(=O)C3CC3)nn2c1 -US20140288046A1,1,CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1.CC1CCCN1>>CC1CCCN1c1nc(C(C)(C)C)nc2c1nnn2Cc1ccccc1Cl -US20050159411A1,6,COc1ccc2nccc([C@@H](O)CN3CC[C@H](NC(=O)OC(C)(C)C)C[C@H]3C(F)(F)F)c2n1>>COc1ccc2nccc([C@@H](O)CN3CC[C@H](N)C[C@H]3C(F)(F)F)c2n1 -US20140323376A1,7,Cc1cc2c(cc1C=O)C(C)(C)[C@@H](C)[C@H](C)C2(C)C>>Cc1cc2c(cc1CO)C(C)(C)[C@@H](C)[C@H](C)C2(C)C -US20120015980A1,6,COC(=O)c1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)nn1-c1ncccc1Cl>>O=C(O)c1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)nn1-c1ncccc1Cl -US20140242099A1,4,CCC(Br)C(=O)c1ccc(C(=O)OC)cc1.Cc1cnc(C(N)=S)cn1>>CCc1sc(-c2cnc(C)cn2)nc1-c1ccc(C(=O)OC)cc1 -US20060211603A1,1,O=C(CBr)OCc1ccccc1.c1ccc(-c2ncc[nH]2)cc1>>O=C(Cn1ccnc1-c1ccccc1)OCc1ccccc1 -US20150038528A1,6,COC(=O)C(=O)CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O>>N#Cc1nc(C(=O)NCCC(=O)C(=O)O)c(O)c2ccc(Oc3ccccc3)cc12 -US07572791B2,3,Cc1cnc(N)c(Br)c1.OB(O)c1ccccc1>>Cc1cnc(N)c(-c2ccccc2)c1 -US05545750,5,COCCl.OC(CCc1ccccc1)CCc1ccccc1>>COCOC(CCc1ccccc1)CCc1ccccc1 -US07595327B2,2,CC(=O)Cl.CCOC(=O)C1CNCCC1NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1>>CCOC(=O)C1CN(C(C)=O)CCC1NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 -US07582761B2,1,FC(F)(F)c1cc(Br)c2nc(Cl)[nH]c2c1.FC(F)(F)c1cnc(N2CCNCC2)c(Cl)c1>>FC(F)(F)c1cnc(N2CCN(c3nc4c(Br)cc(C(F)(F)F)cc4[nH]3)CC2)c(Cl)c1 -US20130012523A1,1,CN.Cc1ccc(C(=O)NC2CC2)cc1-n1ccnc(NC2(c3cc(F)ccc3OCCCl)CC2)c1=O>>CNCCOc1ccc(F)cc1C1(Nc2nccn(-c3cc(C(=O)NC4CC4)ccc3C)c2=O)CC1 -US20120115844A1,2,Cn1nnc(-c2ccc(F)cc2)c1COc1ccc(C(=O)O)nn1.NN1CCOCC1>>Cn1nnc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NN2CCOCC2)nn1 -US20070149510A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCN(c2cccc3c2COC(=O)N3)CC1>>CC(C)(C)OC(=O)N1CCN(c2cccc3c2COC(=O)N3Cc2ccccc2)CC1 -US20020049240A1,1,O=Cc1ccc(F)cc1.OCCN(Cc1ccccc1)c1nc2ccccc2s1>>O=Cc1ccc(OCCN(Cc2ccccc2)c2nc3ccccc3s2)cc1 -US06964961B2,6,CC(C)(C)OC(=O)N1CCC[C@H]1CN1CCOCC1>>C1CN[C@H](CN2CCOCC2)C1 -US09024044B2,6,CC/C(=C\c1ccc(C(=O)OC(C)(C)C)s1)C(=O)OC>>CC/C(=C\c1ccc(C(=O)OC(C)(C)C)s1)C(=O)O -US05605726,1,C=CCBr.C=CCc1ccccc1NC>>C=CCc1ccccc1N(C)CC=C -US04007272,1,CN(C)CCCl.CN1C(=O)c2cscc2Nc2ccccc21>>CN(C)CCN1c2cscc2C(=O)N(C)c2ccccc21 -US04806550,1,CCCC(=O)c1cnc2c(C)cccc2c1Cl.Nc1ccccc1F>>CCCC(=O)c1cnc2c(C)cccc2c1Nc1ccccc1F -US20080171773A1,1,Nc1ccc(Br)cc1F.O=c1cccc[nH]1>>Nc1ccc(-n2ccccc2=O)cc1F -US20090286778A1,2,Nc1cc2cc(c1)Nc1nc(ncc1Cl)Nc1cccc(c1)CC2.O=C(O)C1CCC1>>O=C(Nc1cc2cc(c1)Nc1nc(ncc1Cl)Nc1cccc(c1)CC2)C1CCC1 -US08026255B2,1,CC(C)CBr.COc1ccc(C=O)cc1O>>COc1ccc(C=O)cc1OCC(C)C -US20150141474A1,6,O=C(CC1CCC(c2ccc(-c3ccc(Nc4nnc(C5CCC5)o4)cc3)cc2)CO1)OCc1ccccc1>>O=C(O)CC1CCC(c2ccc(-c3ccc(Nc4nnc(C5CCC5)o4)cc3)cc2)CO1 -US06867207B2,1,CC(C)CO.O=c1cnn(-c2ccc(C(Cl)c3ccc(Cl)cc3)c(Cl)c2)c(=O)[nH]1>>CC(C)COC(c1ccc(Cl)cc1)c1ccc(-n2ncc(=O)[nH]c2=O)cc1Cl -US20050107410A1,1,CC(=O)Nc1cccc(C=O)c1.Cc1ccc2c(OCCN3CCNCC3)cccc2n1>>CC(=O)Nc1cccc(CN2CCN(CCOc3cccc4nc(C)ccc34)CC2)c1 -US05468897,2,C=CCOC(=O)c1ccc(O)cc1.C=Cc1ccc(C(=O)Cl)cc1C12CC3CC(CC(C3)C1)C2>>C=CCOC(=O)c1ccc(OC(=O)c2ccc(C=C)c(C34CC5CC(CC(C5)C3)C4)c2)cc1 -US20140024694A1,5,O=Cc1ccc(F)cc1C(F)(F)F.OCCO>>Fc1ccc(C2OCCO2)c(C(F)(F)F)c1 -US08129376B2,2,Clc1ccccc1OC1CNC1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>O=C(NCC(=O)N1CC(Oc2ccccc2Cl)C1)c1cc(-c2ccccc2)[nH]n1 -US20140303156A1,1,CI.Nc1ccc(F)c(CO)c1>>COCc1cc(N)ccc1F -US20080064676A1,7,COc1ccc(C(=O)CS[C@H]2C(=O)N(c3ccc(F)cc3)[C@@H]2c2ccc(OCC(=O)NCC(=O)N[C@@H](C(=O)O)C(C)C)cc2)cc1>>COc1ccc(C(O)CS[C@H]2C(=O)N(c3ccc(F)cc3)[C@@H]2c2ccc(OCC(=O)NCC(=O)N[C@@H](C(=O)O)C(C)C)cc2)cc1 -US08901156B2,3,O=C(O)c1cncc(B(O)O)c1.O=C(c1ccc(Br)s1)C(F)(F)F>>O=C(O)c1cncc(-c2ccc(C(=O)C(F)(F)F)s2)c1 -US20120107273A1,2,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc(C3CC3)cc2)[C@@H](C(=O)O)C1.NCc1ccc(OC(F)(F)F)cc1>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc(C3CC3)cc2)[C@@H](C(=O)NCc2ccc(OC(F)(F)F)cc2)C1 -US07498356B2,3,Brc1ccc(-c2cccc3c2oc2ccccc23)cc1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1 -US07994317B2,2,CNc1nc(N[C@@H]2CC[C@@H](C(=O)O)CC2)nc(N2CCN(C)CC2)n1.NCc1ccccc1C(F)(F)F>>CNc1nc(N[C@@H]2CC[C@@H](C(=O)NCc3ccccc3C(F)(F)F)CC2)nc(N2CCN(C)CC2)n1 -US20080312231A1,1,COC(=O)C1CCNCC1.COc1ccc(CCl)cc1>>COC(=O)C1CCN(Cc2ccc(OC)cc2)CC1 -US20120035214A1,6,CC(=O)NCCc1ccccc1-c1onc([C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(COCC(F)(F)COC(C)C)cc2)c1Br>>CC(=O)NCCc1ccccc1-c1onc([C@H]2C[NH2+]CC[C@]2(O)c2ccc(COCC(F)(F)COC(C)C)cc2)c1Br -US04778869,1,C=C(C)C(=O)O.CCOC(=O)CCl>>C=C(C)C(=O)OCC(=O)OCC -US20120183660A1,2,N[C@H]1CO[C@@H]2[C@@H](NC(=O)c3cccc(Oc4ccccc4)c3)CO[C@H]12.O=C(O)C1CCC1>>O=C(N[C@H]1CO[C@@H]2[C@@H](NC(=O)C3CCC3)CO[C@H]12)c1cccc(Oc2ccccc2)c1 -US20090048444A1,3,Cc1c(F)cc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1.O=c1ccc2c(Cl)nc(NC(CO)CO)nc2n1-c1c(F)cccc1F>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1nc(NC(CO)CO)nc2c1ccc(=O)n2-c1c(F)cccc1F -US04462821,2,CNC.COC(=O)c1ccccc1C(=O)NN(C)C(=S)Nc1ccccc1>>CN(C)C(=O)c1ccccc1C(=O)NN(C)C(=S)Nc1ccccc1 -US08691822B2,2,CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)O)c4c3OC(C)(C)C4)nc2N1C1CCCC1.N[C@@H]1CC[C@@H](N2CCN(CC3CC3)CC2)CC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)N[C@@H]4CC[C@@H](N5CCN(CC6CC6)CC5)CC4)c4c3OC(C)(C)C4)nc2N1C1CCCC1 -US20150018341A1,3,O=C(Cl)CCCl.c1ccc2c(c1)CCO2>>O=C(CCCl)c1ccc2c(c1)CCO2 -US08222248B2,1,CCOC(=O)CCl.Cc1cc(O)cc(C)c1C=O>>CCOC(=O)COc1cc(C)c(C=O)c(C)c1 -US06919365B2,2,CC1(C)NC(=O)NC1=O.O=S(=O)(Cl)c1ccc2ccccc2c1>>CC1(C)NC(=O)N(S(=O)(=O)c2ccc3ccccc3c2)C1=O -US20140073620A1,7,CC(C)(C)OC(=O)N1CCC(n2cc(Nc3ncc(C(F)(F)F)c(C#Cc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1>>CC(C)(C)OC(=O)N1CCC(n2cc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1 -US07700595B2,1,Nc1cccc(-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1.O=Cc1cc(Cl)ccc1C(F)(F)F>>FC(F)(F)c1ccc(Cl)cc1CNc1cccc(-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1 -US07094798B1,1,O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)ccc2n1CCCBr.Sc1ccccc1>>O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)ccc2n1CCCSc1ccccc1 -US20100094000A1,3,CC1(C)OB(c2ccc3c(c2)NC(=O)CO3)OC1(C)C.Cc1nn(CC2CCC(=O)CC2)c(-c2ccc(F)cc2)c1Br>>Cc1nn(CC2CCC(=O)CC2)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 -US04076712,1,CO.Cc1cc2[nH]c3ncccc3c(=O)n2n1>>Cc1cc2n(C)c3ncccc3c(=O)n2n1 -US20120220563A1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(Br)cc1F>>C=Cc1ccc(Br)cc1F -US20040038872A1,7,COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)O)C[C@H]5C=CCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N4C3)cc(-c3ccccc3)nc2c1>>COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)O)C[C@H]5CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N4C3)cc(-c3ccccc3)nc2c1 -US08604021B2,1,COc1c(Cl)cc(F)cc1C(C)N.CS(=O)(=O)c1ccc(F)cc1F>>COc1c(Cl)cc(F)cc1C(C)Nc1cc(F)ccc1S(C)(=O)=O -US20090326009A1,2,COc1cc(F)ccc1-c1ccc2c(c1CO)C(C)=CC(C)(C)N2.Nc1cccc(C(=O)O)c1>>COc1cc(F)ccc1-c1ccc2c(c1COC(=O)c1cccc(N)c1)C(C)=CC(C)(C)N2 -US20050222395A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)NCC1CN(C(c2ccccc2)c2ccccc2)C1 -US06066644,1,COCCBr.Cc1nnc(-c2ccc(-c3ccc(C(=O)N4CCc5cc6c(cc54)C4(CCNCC4)CO6)cc3)c(C)c2)o1>>COCCN1CCC2(CC1)COc1cc3c(cc12)N(C(=O)c1ccc(-c2ccc(-c4nnc(C)o4)cc2C)cc1)CC3 -US20140112945A1,2,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.COc1ccc(C2=NN(C3CCNCC3)C(=O)[C@@H]3CCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccccc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCC[C@H]23)cc1OC -US20140363452A1,2,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](N)C(C)C.NC1(C(=O)O)CCCCC1>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)C1(N)CCCCC1)C(C)C -US20020052376A1,6,COC(=O)c1ccc(COC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccc(F)cc1>>O=C(O)c1ccc(COC(Cn2ccnc2)c2ccc(F)cc2)cc1-c1ccc(F)cc1 -US06071925,2,O=C(Cl)c1ccccc1.O=C1NCN(c2ccccc2)C12CCN(C1CCc3c(Cl)ccc(Cl)c3C1)CC2>>O=C(c1ccccc1)N1CN(c2ccccc2)C2(CCN(C3CCc4c(Cl)ccc(Cl)c4C3)CC2)C1=O -US05696146,1,CCOC(=O)CCCBr.O=C(Cc1ccc2c(c1)OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)O2)c1c[nH]c2ccccc12>>CCOC(=O)CCCn1cc(C(=O)Cc2ccc3c(c2)OC(c2ccc(Cl)cc2)(c2ccc(Cl)cc2)O3)c2ccccc21 -US20080200501A1,8,OCc1nn(-c2ccc(F)cc2F)c2c1C1CCC2C1>>O=Cc1nn(-c2ccc(F)cc2F)c2c1C1CCC2C1 -US20100121052A1,2,CC(=O)O.Nc1ccc2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc2c1>>CC(=O)Nc1ccc2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc2c1 -US20140005166A1,6,CC(C)(C)OC(=O)N1CCC(Oc2cc(CO)cc(C(F)(F)F)n2)CC1>>OCc1cc(OC2CCNCC2)nc(C(F)(F)F)c1 -US06696461B2,1,CCO.COCc1cn2c(C)c(C)nc2c2c1[C@@H](O)[C@H](O)[C@@H](c1ccccc1)N2>>CCO[C@@H]1c2c(COC)cn3c(C)c(C)nc3c2N[C@H](c2ccccc2)[C@H]1O -US05747499,9,CC(C)(C)OC(=O)CC[C@@H](NC(=O)OCc1ccccc1)C(N)=O>>CC(C)(C)OC(=O)CC[C@H](C#N)NC(=O)OCc1ccccc1 -US07071358B2,2,CC(C)CN(c1ccc(C(O)(C#CC(=O)O)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1.CN>>CNC(=O)C#CC(O)(c1ccc(N(CC(C)C)S(=O)(=O)c2ccccc2)cc1)C(F)(F)F -US20040006141A1,1,CCI.CCOC(=O)C(O)Cc1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(Cc1ccc(OCc2ccccc2)cc1)OCC -US06359138B1,3,C=O.Cc1ccc(CC2(O)CCNCC2)cc1.O=C1CCCc2cc(OCc3ccccc3)ccc21>>Cc1ccc(CC2(O)CCN(CC3CCc4cc(OCc5ccccc5)ccc4C3=O)CC2)cc1 -US20110117016A1,9,[N-]=[N+]=NCCOCCOCCOCCOCCOCCN=[N+]=[N-]>>[N-]=[N+]=NCCOCCOCCOCCOCCOCCN -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=S)Nc4ccc(OC)cc4)cc3)ccc2C1=O>>COc1ccc(NC(=S)Nc2ccc(-c3ccc4c(c3)CN([C@H](C(=O)O)C(C)C)C4=O)cc2)cc1 -US20140303164A1,2,Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@@H](N)Cc3cc(F)cc(F)c3)c21.O=C(O)Cn1nc(C2(O)CC2)c2c1CCCC2>>Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)Cn3nc(C4(O)CC4)c4c3CCCC4)c21 -US20130144054A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H]1CNCCCN1S(=O)(=O)c1ccccc1[N+](=O)[O-]>>C[C@H]1CN(C(=O)OC(C)(C)C)CCCN1S(=O)(=O)c1ccccc1[N+](=O)[O-] -US05243062,7,CCOC(OCC)P(=O)(CC(C#N)Cc1ccccc1)OCC>>CCOC(OCC)P(=O)(CC(CN)Cc1ccccc1)OCC -US04851535,2,CCOC(=O)CC(=O)c1cc(F)c(O)nc1Nc1ccc(F)cc1F.Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>CCOC(=O)CC(=O)c1cc(F)c(OS(=O)(=O)c2c(C)cc(C)cc2C)nc1Nc1ccc(F)cc1F -US20080176832A1,1,C1CCNCC1.CC(C)(C)OC(=O)N1CCc2cn(-c3ccc(Br)cc3)nc2CC1>>CC(C)(C)OC(=O)N1CCc2cn(-c3ccc(N4CCCCC4)cc3)nc2CC1 -US20090221555A1,9,CC1(C)CC(I)C(=O)Nc2cc([N+](=O)[O-])ccc21.[N-]=[N+]=[N-]>>CC1(C)CC(N=[N+]=[N-])C(=O)Nc2cc([N+](=O)[O-])ccc21 -US04402961,7,O=C(Cc1ccccn1)c1ccnc2ccccc12>>c1ccc(CCc2ccnc3ccccc23)nc1 -US20050075453A1,2,C=C(C)C(=O)Cl.CC(C)c1cccc(C(C)C)c1N1C(=O)c2ccc3c4cccc5c(C#CCCCCO)ccc(c6ccc(c2c36)C1=O)c54>>C=C(C)C(=O)OCCCCC#Cc1ccc2c3ccc4c5c(ccc(c6cccc1c62)c53)C(=O)N(c1c(C(C)C)cccc1C(C)C)C4=O -US06300363B1,6,CC(=O)Nc1c(C(=O)c2cc(CO[Si](C)(C)C(C)(C)C)ccn2)[nH]c2cc(Cl)ccc12>>CC(=O)Nc1c(C(=O)c2cc(CO)ccn2)[nH]c2cc(Cl)ccc12 -US04824596,6,CCCCC[C@@H]1CC[C@@H](c2ncc(OC)cn2)CC1>>CCCCC[C@@H]1CC[C@@H](c2ncc(O)cn2)CC1 -US20100093757A1,1,CC(=O)[O-].COCC(Br)C(=O)Nc1ccc(C)cn1>>COCC(OC(C)=O)C(=O)Nc1ccc(C)cn1 -US20120251545A1,6,COCCOCCOc1cccc2c1CN(Cc1ccc(OC)cc1)C2>>COCCOCCOc1cccc2c1CNC2 -US08334309B2,7,C=Cc1n[nH]c2ccc(Nc3nnc(Cc4cccc(OC)c4)o3)cc12>>CCc1n[nH]c2ccc(Nc3nnc(Cc4cccc(OC)c4)o3)cc12 -US20030199578A1,2,Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12.O=C(Cl)CC1CCCC1>>O=C(CC1CCCC1)Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12 -US20130178459A1,6,CC(C)(C)OC(=O)NCc1ccc(-c2c(C#N)ccc3[nH]c(=O)c4sccc4c23)cc1>>N#Cc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(CN)cc1 -US20090099177A1,2,CC(C)COc1ccc(Cl)cc1Cc1cccc(N)n1.COC(=O)c1ccc(C(=O)O)cc1>>COC(=O)c1ccc(C(=O)Nc2cccc(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1 -US05364614,1,ClCC1CO1.c1ccc(CNCc2ccccc2)cc1>>c1ccc(CN(Cc2ccccc2)CC2CO2)cc1 -US20140349990A1,6,COc1ccc(CN2C(=O)c3c(c(C)nn3-c3ccnn3C)C2c2ccc(Cl)cc2)cc1>>Cc1nn(-c2ccnn2C)c2c1C(c1ccc(Cl)cc1)NC2=O -US20110092476A1,2,CC(C)[C@H](C(=O)NC1CC1)n1ccc2c(N)cccc2c1=O.C[C@H](C(=O)O)c1ccc(Cl)cc1>>CC(C)[C@H](C(=O)NC1CC1)n1ccc2c(NC(=O)[C@@H](C)c3ccc(Cl)cc3)cccc2c1=O -US04743293,2,CC(C)(C)C(O)C(=CC1CCCCC1)n1cncn1.O=C=Nc1ccccc1>>CC(C)(C)C(OC(=O)Nc1ccccc1)C(=CC1CCCCC1)n1cncn1 -US05610144,6,CCOC(=O)COc1cccc(NC(=O)NCC(=O)N2[C@H](C(=O)OC(C)(C)C)CS[C@@H]2c2ccccc2)c1>>CC(C)(C)OC(=O)[C@@H]1CS[C@H](c2ccccc2)N1C(=O)CNC(=O)Nc1cccc(OCC(=O)O)c1 -US06262059B1,2,CN=C=O.Nc1nc(NCc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1>>CNC(=O)Nc1nc(NCc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1 -US20100125081A1,9,Cc1cc(C2(c3cccc(Br)c3)N=C(N)c3ncccc32)cc(C2CC2)c1OC(F)F.[C-]#N>>Cc1cc(C2(c3cccc(C#N)c3)N=C(N)c3ncccc32)cc(C2CC2)c1OC(F)F -US06762300B2,1,O=Cc1cc(Br)ccc1O.c1ccc(CN2CCNCC2)cc1>>O=Cc1cc(N2CCN(Cc3ccccc3)CC2)ccc1O -US20100298287A1,7,CCN(CC)c1cccc2nc(C(O)c3ccc(Cl)cc3Cl)n(CCC(=O)OC)c12>>CCN(CC)c1cccc2nc(C(O)c3ccc(Cl)cc3Cl)n(CCCO)c12 -US20110301191A1,2,CCOc1ccc(CC(=O)O)cc1.CN1CCC(NCc2ccc(F)cc2)CC1>>CCOc1ccc(CC(=O)N(Cc2ccc(F)cc2)C2CCN(C)CC2)cc1 -US20100120757A1,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OCc1ccccc1.O=C(CCl)OC(=O)CCl>>COc1ccc(C2=NN(C3CCN(C(=O)CCl)CC3)C(=O)C2(C)C)cc1OCc1ccccc1 -US08183262B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.FC(F)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-n2cnc(Br)c2)n1>>Nc1ccc(-c2cn(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)F)n3)cn2)cn1 -US04505898,6,C=CCOc1ccc(C[C@H](NC(=O)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)OC)cc1Cl>>C=CCOc1ccc(C[C@H](NC(=O)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)O)cc1Cl -US06353111B1,2,CS(=O)(=O)c1ccc(/C(=C\C2CCCCC2)C(=O)O)cc1[N+](=O)[O-].Nc1nccs1>>CS(=O)(=O)c1ccc(/C(=C\C2CCCCC2)C(=O)Nc2nccs2)cc1[N+](=O)[O-] -US06380218B1,2,CC(=O)Cl.Nc1ccc(CNC(=O)c2cccnc2Oc2ccc(F)cc2)cc1>>CC(=O)Nc1ccc(CNC(=O)c2cccnc2Oc2ccc(F)cc2)cc1 -US07326791B2,2,Cc1cc(C(=O)O)ccc1C(=O)N1CCCC1.N[C@@H](CCCCNC(=O)OCc1ccccc1)c1nc2cc(Cl)ccc2[nH]1>>Cc1cc(C(=O)N[C@@H](CCCCNC(=O)OCc2ccccc2)c2nc3cc(Cl)ccc3[nH]2)ccc1C(=O)N1CCCC1 -US06340678B1,2,CN1CCNCC1.O=C(O)/C=C1/c2ccccc2N(C(=O)c2cnn(-c3ccccc3)c2C(F)(F)F)CCC1(F)F>>CN1CCN(C(=O)/C=C2/c3ccccc3N(C(=O)c3cnn(-c4ccccc4)c3C(F)(F)F)CCC2(F)F)CC1 -US20090312569A1,2,CC(C)O.O=C(O)C1CCCCC1>>CC(C)OC(=O)C1CCCCC1 -US20130096118A1,3,C=O.CNC.NC(=O)c1ccc(Br)c2cc[nH]c12>>CN(C)Cc1c[nH]c2c(C(N)=O)ccc(Br)c12 -US20150152092A1,6,CCc1sc(C(=O)OC)cc1-c1ccnn1C>>CCc1sc(C(=O)O)cc1-c1ccnn1C -US07326720B2,2,FC(F)(F)c1cccc(C2CCNCC2)c1.O=C(O)Cc1ccc2nccnc2c1>>O=C(Cc1ccc2nccnc2c1)N1CCC(c2cccc(C(F)(F)F)c2)CC1 -US08877778B2,2,CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCCCC2c2ccoc3cccc2-3)CC1>>CC(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2ccoc3cccc2-3)CC1 -US08362048B2,2,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CC(=O)O)no2)cc1C#N.CNC>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CC(=O)N(C)C)no2)cc1C#N -US20150018373A1,1,Cc1c2cc(-n3ccc(O)cc3=O)ccc2nn1C.OCc1nc(C(F)(F)F)cs1>>Cc1c2cc(-n3ccc(OCc4nc(C(F)(F)F)cs4)cc3=O)ccc2nn1C -US20150284394A1,2,C1COCCN1.CC(C)(C)c1ccc(C(=O)NCc2ccc(-c3ncnc4[nH]c(C(=O)O)cc34)cc2F)cc1>>CC(C)(C)c1ccc(C(=O)NCc2ccc(-c3ncnc4[nH]c(C(=O)N5CCOCC5)cc34)cc2F)cc1 -US07259183B2,1,CC1(c2ccc(C=O)cc2Cl)CC1.NCCc1ccc(Cl)c(Cl)c1>>CC1(c2ccc(CNCCc3ccc(Cl)c(Cl)c3)cc2Cl)CC1 -US08022062B2,1,Cc1ccc(O)cn1.FC(F)(F)CBr>>Cc1ccc(OCC(F)(F)F)cn1 -US20150038437A1,7,CCOC(=O)c1cc2cc(Br)sc2n1C>>Cn1c(CO)cc2cc(Br)sc21 -US08586751B2,3,CCCC[Sn](CCCC)(CCCC)C1=CC(=O)CCC1.NC(=O)c1cc(F)c(Cl)nc1Nc1ccc(N2CCOCC2)cc1>>NC(=O)c1cc(F)c(C2=CC(=O)CCC2)nc1Nc1ccc(N2CCOCC2)cc1 -US20120108577A1,7,CC(=O)c1ccc2c(c1)N(CCN1CCC(NCc3ccc4c(n3)NC(=O)CO4)CC1)C(=O)CO2>>CC(O)c1ccc2c(c1)N(CCN1CCC(NCc3ccc4c(n3)NC(=O)CO4)CC1)C(=O)CO2 -US08163740B2,2,CN1CCN(S(=O)(=O)Cl)CC1.Nc1ccc2c(c1)COC(N[C@@H]1CCCc3ccccc31)=N2>>CN1CCN(S(=O)(=O)Nc2ccc3c(c2)COC(N[C@@H]2CCCc4ccccc42)=N3)CC1 -US20070004757A1,3,CC(=O)N1C(=O)Cc2ccc(F)cc21.COC(=O)CCc1ccc(C(=O)O)cc1>>COC(=O)CCc1ccc(C(O)=C2C(=O)N(C(C)=O)c3cc(F)ccc32)cc1 -US20050282824A1,6,COC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)c1cc(N2CCc3ccccc3C2)nc(Cl)n1>>O=C(N[C@H](Cc1ccc(Cl)cc1)C(=O)O)c1cc(N2CCc3ccccc3C2)nc(Cl)n1 -US20100130474A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(-c2cnc3ccccc3c2)n[nH]1>>CC(C)(C)OC(=O)n1nc(-c2cnc3ccccc3c2)cc1N -US20040082611A1,2,CC1Cc2nc(C(=O)[O-])sc2CN1.COC(=O)CC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1>>COC(=O)CC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1C(=O)c1nc2c(s1)CNC(C)C2 -US20090203692A1,2,CN(C)CC(=O)O.NCc1ccc(Cl)c(NC2=NC(=O)/C(=C/c3ccc4ncccc4c3)S2)c1>>CN(C)CC(=O)NCc1ccc(Cl)c(NC2=NC(=O)/C(=C/c3ccc4ncccc4c3)S2)c1 -US05136868,2,Cc1ccc(S(=O)(=O)Cl)cc1.Oc1ccc(F)cc1Cl>>Cc1ccc(S(=O)(=O)Oc2ccc(F)cc2Cl)cc1 -US04028356,1,NNC1=Nc2ccc(Br)cc2C(c2ccccc2)=NC1.O=C(CO)CCl>>OCC(CCl)=NNC1=Nc2ccc(Br)cc2C(c2ccccc2)=NC1 -US20110144105A1,7,CN(C)C(=O)Cc1cnc2[nH]c(C(CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1>>CN(C)CCc1cnc2[nH]c(C(CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1 -US04992433,1,CCOC(=O)N1CCC(CCCCl)CC1.Oc1ccc(C2=NCCCO2)cc1>>CCOC(=O)N1CCC(CCCOc2ccc(C3=NCCCO3)cc2)CC1 -US20120316161A1,6,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(Cl)cc1OC>>CCCC(C(=O)O)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(Cl)cc1OC -US06403792B1,7,O=C(Nc1ccccc1)[C@H]1CCCN1>>c1ccc(NC[C@H]2CCCN2)cc1 -US08119805B2,2,CN1CCC(N2CCNCC2)CC1.O=S(=O)(O)CC1CCCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1>>CN1CCC(N2CCN(S(=O)(=O)CC3CCCCN3S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)CC1 -US20070105891A1,6,COc1ccncc1[N+](=O)[O-]>>O=[N+]([O-])c1cnccc1O -US20130131118A1,6,CN(C(=O)C(F)(F)F)c1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1Cl>>CNc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1Cl -US20060063772A1,1,CCOC(=O)N1CCNCC1.Cc1ccc(Cl)c(-c2nc(CCl)no2)c1>>CCOC(=O)N1CCN(Cc2noc(-c3cc(C)ccc3Cl)n2)CC1 -US20140121243A1,1,Brc1ccc2[nH]ncc2c1.CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1>>CC(C)(C)OC(=O)N1CCC(n2ncc3cc(Br)ccc32)CC1 -US20110301142A1,3,CCOC(=O)Cc1ccc(Br)cc1.Cc1noc(-c2cccc(B3OC(C)(C)C(C)(C)O3)c2)c1NC(=O)OC(C)c1ccccc1Cl>>CCOC(=O)Cc1ccc(-c2cccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)c2)cc1 -US20150065550A1,3,COC(=O)C(Cl)SCCc1ccccc1Br>>COC(=O)C1SCCc2c(Br)cccc21 -US20060229309A1,6,CCCCN(C)C(=O)c1cccc(C(=O)OC)c1>>CCCCN(C)C(=O)c1cccc(C(=O)O)c1 -US20090186898A1,2,C1COCCN1.O=C(O)c1ccc(Cl)nc1>>O=C(c1ccc(Cl)nc1)N1CCOCC1 -US04369184,7,CCOC(=O)C1(c2ccccc2)CCN(C2=CCC(C#N)(c3ccccn3)CC2)CC1>>CCOC(=O)C1(c2ccccc2)CCN(C2CCC(C#N)(c3ccccn3)CC2)CC1 -US06552200B2,9,O=C(c1ccc(CBr)cc1)C1CC1.[C-]#N>>N#CCc1ccc(C(=O)C2CC2)cc1 -US08809380B2,2,Nc1ccon1.O=C(O)c1ncccc1OC[C@H]1C[C@@H](OCOCc2ccccc2)CN1C(=O)[C@@H]1CC[C@@H](C(F)(F)F)CC1>>O=C(Nc1ccon1)c1ncccc1OC[C@H]1C[C@@H](OCOCc2ccccc2)CN1C(=O)[C@@H]1CC[C@@H](C(F)(F)F)CC1 -US06353006B1,1,BrC1CCCC1.COC(=O)c1ccc(N=C2NC3(CCCC3)CS2)c(C)c1>>COC(=O)c1ccc(N=C2SCC3(CCCC3)N2C2CCCC2)c(C)c1 -US20040058965A1,1,CC(Nc1nc(-c2ccccc2)cs1)c1ccc(CO)cc1.COC(=O)Cc1ccc(O)cc1>>COC(=O)Cc1ccc(OCc2ccc(C(C)Nc3nc(-c4ccccc4)cs3)cc2)cc1 -US20120157494A1,7,COCC(C)N1Cc2c(cccc2[N+](=O)[O-])C1=O>>COCC(C)N1Cc2c(N)cccc2C1=O -US06022978,1,CCC(=O)CC.Cc1cc(C)c(-c2cccc(N)c2NC(=O)OC(C)(C)C)c(C)c1>>CCC(CC)Nc1cccc(-c2c(C)cc(C)cc2C)c1NC(=O)OC(C)(C)C -US20130143892A1,2,Cc1cnc(N2CCC(NC3CC3)CC2)nc1.O=C(O)c1ccc(-c2cnco2)nc1>>Cc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)nc3)C3CC3)CC2)nc1 -US04923891,8,CCCc1c(OCCCSCC2COC(CCC(=O)O)(CCC(=O)O)S2)ccc(C(C)=O)c1O.O=C(OO)c1ccccc1Cl>>CCCc1c(OCCCS(=O)CC2COC(CCC(=O)O)(CCC(=O)O)S2)ccc(C(C)=O)c1O -US07576098B2,1,CCOc1cc(OC(C)C)c(F)c(C(Cl)c2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1.Nc1ccc2cnccc2c1>>CCOc1cc(OC(C)C)c(F)c(C(Nc2ccc3cnccc3c2)c2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1 -US07910592B2,6,COC(=O)Cc1ccc(OC)c(-c2ccc(C3CC3)nc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)c1>>COc1ccc(CC(=O)O)cc1-c1ccc(C2CC2)nc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C -US20060030609A1,7,O=C1C(=O)N(CCF)c2ccccc21>>O=C1Cc2ccccc2N1CCF -US07790728B2,3,Nc1cnc(Br)c(-c2cccc(F)c2)n1.OB(O)c1ccncc1Cl>>Nc1cnc(-c2ccncc2Cl)c(-c2cccc(F)c2)n1 -US20070082912A1,6,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(Cl)c(Cl)c2)c1>>Cc1ccc(-c2cc(Br)ccc2OCc2ccc(Cl)c(Cl)c2)n1-c1cccc(C(=O)O)c1 -US05279946,2,COC(=O)[C@@H](N)Cc1ccccc1.O=C(O)C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1 -US08946261B2,1,CI.O=C(Nc1ccccc1F)Oc1ccc2c(c1)NCCC2>>CN1CCCc2ccc(OC(=O)Nc3ccccc3F)cc21 -US20100256134A1,1,CCOC(=O)c1cnn2c(Cl)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12.Cc1ncccc1N>>CCOC(=O)c1cnn2c(Nc3cccnc3C)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12 -US07838087B2,7,CCCC1CCC(C2CCC(C=Cc3ccc(OCC)c(F)c3C(F)F)CC2)CC1>>CCCC1CCC(C2CCC(CCc3ccc(OCC)c(F)c3C(F)F)CC2)CC1 -US08546400B2,1,CS(=O)(=O)Nc1cccc(N)c1.Clc1ncc(-c2ccc3cnccc3c2)o1>>CS(=O)(=O)Nc1cccc(Nc2ncc(-c3ccc4cnccc4c3)o2)c1 -US04851540,1,COc1ccc(CCl)cc1.C[C@H](c1ccccc1)N1C(=O)N[C@@H]2C(=O)OC[C@@H]21>>COc1ccc(CN2C(=O)N([C@H](C)c3ccccc3)[C@H]3COC(=O)[C@H]32)cc1 -US08119624B2,1,CN(C)C(=O)c1ccc(Br)cc1.COC(=O)c1cc(O)c2c(c1)OC(C)(C)C2>>COC(=O)c1cc(Oc2ccc(C(=O)N(C)C)cc2)c2c(c1)OC(C)(C)C2 -US20150099730A1,2,NC(=O)C1(N)CCCC1.O=C(O)c1ccc(Br)cc1>>NC(=O)C1(NC(=O)c2ccc(Br)cc2)CCCC1 -US04127720,2,CC(C)C(=O)Cl.O=C(O)c1cnc2n(c1=O)CCc1ccc(O)cc1-2>>CC(C)C(=O)Oc1ccc2c(c1)-c1ncc(C(=O)O)c(=O)n1CC2 -US20110230446A1,6,C[C@@H](C[C@@H](CO)NC(=O)OCc1ccccc1)C(F)(F)F>>C[C@@H](C[C@H](N)CO)C(F)(F)F -US04824846,1,Cc1cc(N2CCNCC2)cc(C)c1O.Cc1nc(-c2ccccc2)nc(Cl)c1C>>Cc1cc(N2CCN(c3nc(-c4ccccc4)nc(C)c3C)CC2)cc(C)c1O -US20110251204A1,2,CC[C@H](C)[C@@H](CNc1ccc(O[Si](C)(C)C(C)(C)C)cc1)NC(=O)OC(C)(C)C.O=C(O)[C@@H]1C[C@H]1c1ccccn1>>CC[C@H](C)[C@@H](CN(C(=O)[C@@H]1C[C@H]1c1ccccn1)c1ccc(O[Si](C)(C)C(C)(C)C)cc1)NC(=O)OC(C)(C)C -US07612076B2,6,CC(=O)N(C)c1ccnc(N2CCN(C(C)C)CC2)c1>>CNc1ccnc(N2CCN(C(C)C)CC2)c1 -US04661145,1,Cc1cc(=O)c(C(=O)O)nn1-c1ccc(Cl)cc1.Oc1ccccc1>>Cc1cc(=O)c(C(=O)Oc2ccccc2)nn1-c1ccc(Cl)cc1 -US20130274469A1,6,CCOC(=O)c1conc1-c1ccccn1>>O=C(O)c1conc1-c1ccccn1 -US20090136473A1,1,COc1ccc(Cc2ccc(F)nc2)c(F)c1-c1cccc(Cl)c1.O=C(O)[C@@H]1CCCN1>>COc1ccc(Cc2ccc(N3CCC[C@H]3C(=O)O)nc2)c(F)c1-c1cccc(Cl)c1 -US20060137207A1,7,CCCCCCC=CCc1cccc2c(=O)c(O)c(-c3cc(OC)c(OC)cc3OC)oc12>>CCCCCCCCCc1cccc2c(=O)c(O)c(-c3cc(OC)c(OC)cc3OC)oc12 -US20120190666A1,2,COc1cccc(CC(=O)O)c1.Cc1nc(N)cc(-c2c(Nc3ccn(C)n3)nc3ccccn23)n1>>COc1cccc(CC(=O)Nc2cc(-c3c(Nc4ccn(C)n4)nc4ccccn34)nc(C)n2)c1 -US20110003786A1,6,CC(=O)Nc1nc2c(s1)-c1nc(CC3CC3)sc1CC2>>Nc1nc2c(s1)-c1nc(CC3CC3)sc1CC2 -US04204991,6,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)N(C(=O)OC(C)(C)C)[N+](=O)[O-])C(C)C>>COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)N[N+](=O)[O-])C(C)C -US20120220609A1,7,CCOC(=O)C(C)(C)c1ccc(-c2ccc(Br)cc2)cc1>>CC(C)(CO)c1ccc(-c2ccc(Br)cc2)cc1 -US20110105514A1,9,CCc1nc(I)c(I)n1CCNC(=O)OC(C)(C)C>>CCc1nc(I)cn1CCNC(=O)OC(C)(C)C -US06924292B2,2,COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)Cl)cc1)=NC(C)(C)C2.Nc1ccncc1>>COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)Nc3ccncc3)cc1)=NC(C)(C)C2 -US08084620B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc(NC(=O)OC(C)(C)C)sc1Br>>Cc1nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)sc1Br -US08299085B2,1,Brc1c[nH]cn1.CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc2c1=O>>CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(-n3cnc(Br)c3)cc2c1=O -US04026936,7,Nc1ccc(C(=O)c2nccs2)cc1[N+](=O)[O-]>>Nc1ccc(C(=O)c2nccs2)cc1N -US20070003680A1,3,CC(C)CNC(=O)C(C)(C)c1ccc(Br)cc1.OB(O)c1cccc(O)c1>>CC(C)CNC(=O)C(C)(C)c1ccc(-c2cccc(O)c2)cc1 -US07226938B2,2,C1CNCCN1.O=C(O)c1cc2sccc2[nH]1>>O=C(c1cc2sccc2[nH]1)N1CCNCC1 -US09096598B2,1,Brc1cncc(Br)c1.N[C@H]1CCCC[C@H]1C(=O)NCC(F)(F)F>>O=C(NCC(F)(F)F)[C@@H]1CCCC[C@@H]1Nc1cncc(Br)c1 -US08492437B2,6,COC(=O)Cc1ccc(Oc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(CNS(=O)(=O)c2ccc(F)cc2)c1>>O=C(O)Cc1ccc(Oc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(CNS(=O)(=O)c2ccc(F)cc2)c1 -US20150148342A1,1,CI.O=C1COc2ccc(Br)c(Oc3ccccc3)c2N1>>CN1C(=O)COc2ccc(Br)c(Oc3ccccc3)c21 -US20140140956A1,1,C1COCCN1.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCBr)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCN4CCOCC4)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1 -US20090181942A1,6,CCOC(=O)CC1CCN(C(=O)C[C@H]2O[C@H](C(=O)c3cccc(Cl)c3Cl)c3cc(Cl)ccc3-n3cccc32)CC1>>O=C(O)CC1CCN(C(=O)C[C@H]2O[C@H](C(=O)c3cccc(Cl)c3Cl)c3cc(Cl)ccc3-n3cccc32)CC1 -US07897611B2,3,C#C[Si](C)(C)C.CC(C)(C)OC(=O)N1CC2CC=C(OS(=O)(=O)C(F)(F)F)C1C2>>CC(C)(C)OC(=O)N1CC2CC=C(C#C[Si](C)(C)C)C1C2 -US20110245257A1,3,COC(=O)c1cccc2nc([C@H](C)NC(=O)OCc3ccccc3)c(I)n12.OB(O)c1cncc(F)c1>>COC(=O)c1cccc2nc([C@H](C)NC(=O)OCc3ccccc3)c(-c3cncc(F)c3)n12 -US04703054,2,CC1NC(C)(C)NC1=O.O=C(O)CNC(=O)OCc1ccccc1>>CC1C(=O)NC(C)(C)N1C(=O)CNC(=O)OCc1ccccc1 -US08436008B2,2,CC1Cc2ccc(-c3ncc(C(=O)O)s3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1.CN>>CNC(=O)c1cnc(-c2ccc3c(c2)CN(c2cc(N4CCN(C)CC4)nc(N)n2)C(C)C3)s1 -US05691330,7,O=C(CCl)c1cc2c(s1)C(=O)NCCC2>>O=C1NCCCc2cc(CCCl)sc21 -US20150232476A1,1,CC(C)(C)OC(=O)CBr.NC(=O)c1c(NC(=O)Nc2ccc(Cl)cc2)sc2c1CCNC2>>CC(C)(C)OC(=O)CN1CCc2c(sc(NC(=O)Nc3ccc(Cl)cc3)c2C(N)=O)C1 -US20110124642A1,2,Nn1nc(C2CC2)c2ccccc2c1=O.O=C(O)Cc1ccc(Cl)cc1>>O=C(Cc1ccc(Cl)cc1)Nn1nc(C2CC2)c2ccccc2c1=O -US20150094333A1,1,CC(C)(C)S(=O)(=O)c1cc2c(Cl)ccnc2cc1O.COCCCBr>>COCCCOc1cc2nccc(Cl)c2cc1S(=O)(=O)C(C)(C)C -US08314062B2,2,C=C[C@@H]1C[C@]1([NH3+])C(=O)NS(=O)(=O)C1CC1.O=C(O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1CCCCC1)NCCCCC=Cc1cccc(c1)-c1cccc(c1)CO2>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1CCCCC1)NCCCCC=Cc1cccc(c1)-c1cccc(c1)CO2)C(=O)NS(=O)(=O)C1CC1 -US20120264733A1,1,CC(C)CN(C(=O)c1nc2ccccc2[nH]1)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1.CS(=O)(=O)OCCc1cccs1>>CC(C)CN(C(=O)c1nc2ccccc2n1CCc1cccs1)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1 -US20080255152A1,7,COC1C(=O)N(C)CCc2ccccc21>>COC1CN(C)CCc2ccccc21 -US20090018166A1,2,CCCCC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCC1=O.NS(=O)(=O)CC1CCCC1>>CCCCC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)CC3CCCC3)CC2)nc1CN1CCCC1=O -US06162918,2,CNOC.O=C(O)c1ccc(Cl)c(Br)c1>>CON(C)C(=O)c1ccc(Cl)c(Br)c1 -US07049444B2,2,CC1(c2cccc(N)c2)C2CN(CCCc3ccccc3)CC21.COCCS(=O)(=O)Cl>>COCCS(=O)(=O)Nc1cccc(C2(C)C3CN(CCCc4ccccc4)CC32)c1 -US20150210635A1,6,COC(=O)C12CC3CC(C1)C(NC(=O)C1(CNS(=O)(=O)c4ccccc4F)CC1)C(C3)C2>>O=C(O)C12CC3CC(C1)C(NC(=O)C1(CNS(=O)(=O)c4ccccc4F)CC1)C(C3)C2 -US20150166564A1,2,CC(=O)OC(C)=O.COCCN1C[C@@H](NC(=O)Nc2c(Br)c(C3CCNCC3)nn2-c2ccccc2)[C@H](c2ccc(F)c(F)c2)C1>>COCCN1C[C@@H](NC(=O)Nc2c(Br)c(C3CCN(C(C)=O)CC3)nn2-c2ccccc2)[C@H](c2ccc(F)c(F)c2)C1 -US06342498B1,1,COc1ccccc1N1CCN(C(=O)CCCCCBr)CC1.Fc1ccc2c(C3=CCNCC3)c[nH]c2c1>>COc1ccccc1N1CCN(C(=O)CCCCCN2CC=C(c3c[nH]c4cc(F)ccc34)CC2)CC1 -US20140371283A1,8,O=C(c1cc(F)cc(F)c1)C(O)c1cccc(OC(F)F)c1>>O=C(C(=O)c1cccc(OC(F)F)c1)c1cc(F)cc(F)c1 -US08901115B2,2,CCOC(=O)C(=O)Cl.Nc1c(F)ccc(Cl)c1F>>CCOC(=O)C(=O)Nc1c(F)ccc(Cl)c1F -US20060205774A1,2,CS(=O)(=O)Cl.O=C(C1CCOCC1)N1CCC(c2ccc(OCCCO)cc2)CC1>>CS(=O)(=O)OCCCOc1ccc(C2CCN(C(=O)C3CCOCC3)CC2)cc1 -US09150508B2,6,COC(=O)Cc1ccc(S(=O)(=O)N(CC(C)C)c2ccc(C)cc2C)cc1>>Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(CC(=O)O)cc2)c(C)c1 -US08785441B2,2,Cn1nccc1-c1cc(N)ccc1OCCN1CCCOCC1.O=C(Cl)c1cccc(C(F)(F)F)c1>>Cn1nccc1-c1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1OCCN1CCCOCC1 -US04336257,4,Nc1ccc(Cl)cc1N.O=C(O)c1ccncc1>>Clc1ccc2nc(-c3ccncc3)[nH]c2c1 -US20070088001A1,2,C[Si](C)(C)CC(NC(=O)c1cccc(I)c1)C(=O)O.N#CC1(N)CC1>>C[Si](C)(C)CC(NC(=O)c1cccc(I)c1)C(=O)NC1(C#N)CC1 -US20090054427A1,3,CC1(c2cccc(Br)c2)COC1.CN(C)C=O>>CC1(c2cccc(C=O)c2)COC1 -US06235731B1,7,CCOC(=O)CC1=CCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CC=C(CCO)C1 -US20090247507A1,1,Nc1ncc(Br)c(Cl)c1[N+](=O)[O-].c1cc(CN2CCNCC2)ccn1>>Nc1ncc(Br)c(N2CCN(Cc3ccncc3)CC2)c1[N+](=O)[O-] -US06350907B1,7,C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C/C=C/c1ccc(-c2ccccc2)c(Cl)c1)CC(=O)OC(C)(C)C)C(C)(C)C)c1ccccc1>>C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(-c2ccccc2)c(Cl)c1)CC(=O)OC(C)(C)C)C(C)(C)C)c1ccccc1 -US07932272B2,6,O=C1c2ccccc2C(=O)N1Cc1ccc(OCc2ccccc2)cc1>>NCc1ccc(OCc2ccccc2)cc1 -US08063099B2,2,Cc1ccc(-c2ccccc2C(=O)O)cc1C.Cc1nc2sccn2c1C(=O)NC[C@H]1NC[C@@H]2C[C@H]12>>Cc1ccc(-c2ccccc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2c(C)nc3sccn23)cc1C -US20100227902A1,2,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1Cl.Nc1ccc(Cl)cc1C(=O)c1ccccc1>>CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2ccccc2)cc1Cl -US20100249066A1,2,CC(C)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n(C3CCC(O)(C(=O)O)CC3)c2n1.NC1CCCC1>>CC(C)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n(C3CCC(O)(C(=O)NC4CCCC4)CC3)c2n1 -US20070232632A1,1,CCC(=O)Cl.CS(=N)(=O)c1ccc([N+](=O)[O-])cc1>>CCC(=O)N=S(C)(=O)c1ccc([N+](=O)[O-])cc1 -US06815458B2,7,N#Cc1ccc(CO)cc1>>NCc1ccc(CO)cc1 -US20100022515A1,1,CC(C)(C)OC(=O)N1CCC(CCCOS(C)(=O)=O)CC1.CS(=O)(=O)N1CCc2cc(O)ccc2C1>>CC(C)(C)OC(=O)N1CCC(CCCOc2ccc3c(c2)CCN(S(C)(=O)=O)C3)CC1 -US08604021B2,1,CN(C)C1CCNCC1.COc1cc(Cl)cc(C(C)Nc2cc(F)ccc2S(C)(=O)=O)c1OC>>COc1cc(Cl)cc(C(C)Nc2cc(N3CCC(N(C)C)CC3)ccc2S(C)(=O)=O)c1OC -US07074813B2,1,COC(=O)c1cc([N+](=O)[O-])ccc1Cl.Oc1ccccc1>>COC(=O)c1cc([N+](=O)[O-])ccc1Oc1ccccc1 -US20110118236A1,2,CC1(C)Cc2cc(Cl)cc(N)c2O1.O=C(O)Cn1nc(C(F)(F)F)c2c1CCCC2>>CC1(C)Cc2cc(Cl)cc(NC(=O)Cn3nc(C(F)(F)F)c4c3CCCC4)c2O1 -US20050032838A1,1,CSc1cccc(O)c1.O=C(N[C@@H]1CC[C@@H](O)CC1)c1cc(F)cnc1Cl>>CSc1cccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@@H](O)CC2)c1 -US05273999,1,CCOC(=O)CCCBr.COC(=O)/C=C/c1c(O)cccc1C#CCCCCOC1CCCCO1>>CCOC(=O)CCCOc1cccc(C#CCCCCOC2CCCCO2)c1/C=C/C(=O)OC -US04406690,1,CI.Cc1ccc(O)cn1>>COc1ccc(C)nc1 -US08288537B2,8,CC(C(=O)NC(CC(=O)OC(C)(C)C)C(O)COC(=O)c1c(Cl)cccc1Cl)n1ccc2ccccc2c1=O>>CC(C(=O)NC(CC(=O)OC(C)(C)C)C(=O)COC(=O)c1c(Cl)cccc1Cl)n1ccc2ccccc2c1=O -US20140243349A1,1,COc1c2c(cc(Br)c1C(C)=O)OCCO2.C[O-]>>COc1cc2c(c(OC)c1C(C)=O)OCCO2 -US04698345,2,CC(=O)O.CCCc1c2nc(C(=O)OCC)cc(NC)c2cc2c(=O)cc(C(=O)OCC)oc12>>CCCc1c2nc(C(=O)OCC)cc(N(C)C(C)=O)c2cc2c(=O)cc(C(=O)OCC)oc12 -US20120028931A1,1,CCOP(=O)(CC(N)=NOC(=O)c1cccc(C)n1)OCC>>CCOP(=O)(Cc1noc(-c2cccc(C)n2)n1)OCC -US20070208046A1,3,C=Cc1ccc(F)cc1.COc1ccc(COc2cc(I)ccn2)cc1>>COc1ccc(COc2cc(/C=C/c3ccc(F)cc3)ccn2)cc1 -US08507489B2,6,Cc1ccc2nnc(Sc3ccc4ncc(-c5cnn(C6CN(C(=O)OC(C)(C)C)C6)c5)cc4c3)n2n1>>Cc1ccc2nnc(Sc3ccc4ncc(-c5cnn(C6CNC6)c5)cc4c3)n2n1 -US03984474,4,C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CCC2=O.OO>>C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC45O[C@H]4C(=O)CC[C@@]53C)[C@@H]1CCC2=O -US04689338,9,N.OCCn1cnc2c(Cl)nc3ccccc3c21>>Nc1nc2ccccc2c2c1ncn2CCO -US20100019229A1,3,CCCCOP(=O)(OCCCC)c1ccsc1I.CCCCOP(=O)(OCCCC)c1ccsc1[Sn](CCCC)(CCCC)CCCC>>CCCCOP(=O)(OCCCC)c1ccsc1-c1sccc1P(=O)(OCCCC)OCCCC -US20140128408A1,2,CS(=O)(=O)Cl.NCCc1c[nH]c2ccccc12>>CS(=O)(=O)NCCc1c[nH]c2ccccc12 -US04496735,1,Brc1cccnc1.O=Cc1ccc(O)cc1>>O=Cc1ccc(Oc2cccnc2)cc1 -US20090054435A1,6,COCOc1cc(OC)ccc1C(=O)c1cccc(OCc2nc(-c3ccccc3)oc2C)c1>>COc1ccc(C(=O)c2cccc(OCc3nc(-c4ccccc4)oc3C)c2)c(O)c1 -US05262425,6,CCOC(=O)CC(O)[C@H]1[C@H](N(Cc2ccc(OC)cc2)C(=O)OC(C)(C)C)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1>>CCOC(=O)CC(O)[C@H]1[C@H](NC(=O)OC(C)(C)C)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 -US20090005353A1,1,CC(C)(C)N1C(=O)C(NC2CCNCC2)=C(c2ccccc2)S1(=O)=O.N#Cc1ccc(CBr)cc1>>CC(C)(C)N1C(=O)C(NC2CCN(Cc3ccc(C#N)cc3)CC2)=C(c2ccccc2)S1(=O)=O -US20070142371A1,9,CC(C)(COCc1ccccc1)C(=O)O.N>>CC(C)(COCc1ccccc1)C(N)=O -US06242470B1,2,Nc1cccc2[nH]ccc12.O=C(Cl)CC12CC3CC(CC(C3)C1)C2>>O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cccc2[nH]ccc12 -US05496817,9,CCOC(=O)CN1C(=O)C(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)Sc2ccccc21.N>>CC(C)(C)c1cc(C=C2Sc3ccccc3N(CC(N)=O)C2=O)cc(C(C)(C)C)c1O -US20060079548A1,1,CNC(=O)c1c(C)n(C)c2cc(O)ccc12.COc1cccc(-c2cc3nccc(Cl)c3s2)n1>>CNC(=O)c1c(C)n(C)c2cc(Oc3ccnc4cc(-c5cccc(OC)n5)sc34)ccc12 -US06579872B1,1,CCNCC.Cc1ccc(NC(=O)c2ccc(C#N)cc2)cc1NC(=O)c1ccc(CCl)cc1>>CCN(CC)Cc1ccc(C(=O)Nc2cc(NC(=O)c3ccc(C#N)cc3)ccc2C)cc1 -US08729271B2,1,CC(C)(C)OC(=O)CBr.NC1CCC1>>CC(C)(C)OC(=O)CNC1CCC1 -US08633216B2,6,COC(=O)c1ccc2cnc(C(=O)c3ccc(N)c(OC)c3)n2c1>>COc1cc(C(=O)c2ncc3ccc(C(=O)O)cn23)ccc1N -US07579347B2,3,CCCC[Sn](CCCC)(CCCC)c1nccs1.O=C(/C=C/c1ccc(C(F)(F)F)cc1Br)Nc1ccc2[nH]ccc2c1>>O=C(/C=C/c1ccc(C(F)(F)F)cc1-c1nccs1)Nc1ccc2[nH]ccc2c1 -US20100063117A1,1,C1COC2(CNCC23CC3)O1.O=[N+]([O-])c1cc(F)c(F)c(F)c1>>O=[N+]([O-])c1cc(F)c(N2CC3(CC3)C3(C2)OCCO3)c(F)c1 -US04564479,3,C=C(C)C(=O)OCC.O=[N+]([O-])c1ccc(Br)cc1>>CCOC(=O)C(C)=Cc1ccc([N+](=O)[O-])cc1 -US20110178033A1,3,C#C[Si](C)(C)C.Cc1ccc([C@@]2(O)O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1>>Cc1ccc([C@@]2(O)O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(C#C[Si](C)(C)C)cc1 -US20060173018A1,6,Cc1ccc2c(N3CCC(NC(=O)OC(C)(C)C)CC3)nc(-c3c(O)cccc3F)nc2c1>>Cc1ccc2c(N3CCC(N)CC3)nc(-c3c(O)cccc3F)nc2c1 -US20130178459A1,3,COc1cc(C)c2c(c1Br)c1cc(C)sc1c(=O)n2COCC[Si](C)(C)C.C[C@@H](CNC(=O)OC(C)(C)C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>COc1cc(C)c2c(c1-c1ccc([C@@H](C)CNC(=O)OC(C)(C)C)cc1)c1cc(C)sc1c(=O)n2COCC[Si](C)(C)C -US20110082164A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(O)c1cn(Cc2cccc(C(F)(F)F)c2)nn1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)c4cn(Cc5cccc(C(F)(F)F)c5)nn4)cc3)cc2)CC1 -US08063046B2,2,CC(N)CO.COc1ccc(C(=O)O)cc1/C=C/c1ccc(OC(F)(F)F)cc1>>COc1ccc(C(=O)NC(C)CO)cc1/C=C/c1ccc(OC(F)(F)F)cc1 -US20100035871A1,3,OB(O)c1ccc(Cl)cc1C(F)(F)F.[N-]=[N+]=NCC1CNc2cccc(Br)c2O1>>[N-]=[N+]=NCC1CNc2cccc(-c3ccc(Cl)cc3C(F)(F)F)c2O1 -US05162326,8,CCCSc1cc(=O)n(CCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.O=C(OO)c1cccc(Cl)c1>>CCCn1c(=O)cc(S(=O)CCC)n(Cc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c1=O -US20090054407A1,2,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.Cc1noc(C)c1S(=O)(=O)Cl>>Cc1noc(C)c1S(=O)(=O)Oc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O -US06262059B1,1,COc1cc2nc(Cl)nc(N)c2cc1OC.O=C(C1=CCCC1)N1CCNCC1>>COc1cc2nc(N3CCN(C(=O)C4=CCCC4)CC3)nc(N)c2cc1OC -US20150152108A1,1,Clc1ccc2c(n1)N[C@H]1CCCN2C1.FC(F)(F)C1CCCNC1>>FC(F)(F)C1CCCN(c2ccc3c(n2)N[C@H]2CCCN3C2)C1 -US04336397,6,COC(=O)C(=O)CC(=O)c1ccc(Cc2ccc(Cl)c(Cl)c2)cc1>>O=C(O)C(=O)CC(=O)c1ccc(Cc2ccc(Cl)c(Cl)c2)cc1 -US05532248,6,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O[Si](C)(C)C(C)(C)C)C(OC)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)C(OC)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC -US20050222395A1,6,CC(C)(C)OC(=O)NCCC1CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)NCCC1CCNC1 -US08044069B2,2,FC(F)(F)c1ccc2c(c1)CNC2.O=C(O)CN1CCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCC(c2ccccc2)(c2ccccc2)C1=O)N1Cc2ccc(C(F)(F)F)cc2C1 -US08088767B2,7,CC(C)(C)OC(=O)N1CCN(CCCOc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1>>CC(C)(C)OC(=O)N1CCN(CCCOc2ccc(N)c(C(F)(F)F)c2)CC1 -US07964724B2,2,CC(C)(C)c1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)Cl)c(OCC(F)(F)F)c1.CS(=O)(=O)CCN1CCNCC1>>CC(C)(C)c1ccc(C2=N[C@@H](c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N2C(=O)N2CCN(CCS(C)(=O)=O)CC2)c(OCC(F)(F)F)c1 -US20120208732A1,2,C=CCCCCCCCCO.CCCCCCCC/C=C\CCCCCCCC(=O)Cl>>C=CCCCCCCCCOC(=O)CCCCCCC/C=C\CCCCCCCC -US20060160820A1,2,O=C(Cl)Oc1ccc(Cc2ccc(C(F)(F)F)cc2)cc1.c1ccc(CN2CCNCC2)nc1>>O=C(Oc1ccc(Cc2ccc(C(F)(F)F)cc2)cc1)N1CCN(Cc2ccccn2)CC1 -US20130196982A1,3,CCNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.C[C@H]1COCCN1c1nccc(Cl)n1>>CCNC(=O)Nc1ccc(-c2ccnc(N3CCOC[C@@H]3C)n2)cc1 -US08034812B2,2,COc1cccc(C(=O)O)c1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>COc1cccc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)c1 -US08841455B2,3,Cc1nnc(Cn2nc(Br)c3c([N+](=O)[O-])cccc32)s1.OB(O)C1CC1>>Cc1nnc(Cn2nc(C3CC3)c3c([N+](=O)[O-])cccc32)s1 -US06391891B1,2,CN1CCC(c2c[nH]c3ccc(N)cc23)CC1.O=C(O)Cc1ccc(-c2ccncc2)c2ccccc12>>CN1CCC(c2c[nH]c3ccc(NC(=O)Cc4ccc(-c5ccncc5)c5ccccc45)cc23)CC1 -US08236837B2,7,CCC(=O)NCC=C1CCc2ccc3nc(C)oc3c21>>CCC(=O)NCCC1CCc2ccc3nc(C)oc3c21 -US20100048555A1,2,CCOC(=O)c1sc2c(N)ncn2c1C(F)(F)F.CN1CCN(c2ccc(C(=O)Cl)cc2)CC1>>CCOC(=O)c1sc2c(NC(=O)c3ccc(N4CCN(C)CC4)cc3)ncn2c1C(F)(F)F -US20130274260A1,3,COC(=O)c1cccc(CBr)c1.OB(O)c1cccc(F)c1>>COC(=O)c1cccc(Cc2cccc(F)c2)c1 -US07560558B2,1,COc1cc2c(Oc3cc(C)c(C)nc3-c3ccc(C)cn3)ccnc2cc1OCCCl.NCCO>>COc1cc2c(Oc3cc(C)c(C)nc3-c3ccc(C)cn3)ccnc2cc1OCCNCCO -US20040192708A1,2,CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(N)cc3)nc21.Cc1nn(C)c(Cl)c1S(=O)(=O)Cl>>CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(NS(=O)(=O)c4c(C)nn(C)c4Cl)cc3)nc21 -US20100298314A1,9,[N-]=[N+]=NCc1cc(-c2ccccc2)on1>>NCc1cc(-c2ccccc2)on1 -US05326870,2,NCCN1CCN(CCCSc2ccccc2)CC1.O=S(=O)(O)c1ccc(Cl)c2ncccc12>>O=S(=O)(NCCN1CCN(CCCSc2ccccc2)CC1)c1ccc(Cl)c2ncccc12 -US20030166650A1,2,CC(N)c1cccc(N2CCO[C@@H](CNC(=O)OC(C)(C)C)C2)c1.O=C(O)C=Cc1ccc(F)c(F)c1>>CC(NC(=O)C=Cc1ccc(F)c(F)c1)c1cccc(N2CCO[C@@H](CNC(=O)OC(C)(C)C)C2)c1 -US20070135427A1,2,Nc1ccc(-c2cnco2)cc1.O=C(O)C(=O)CC1(c2ccccc2C(F)(F)F)CCC1>>O=C(CC1(c2ccccc2C(F)(F)F)CCC1)C(=O)Nc1ccc(-c2cnco2)cc1 -US20120129793A1,6,CC(C)(CCS(=O)(=O)CCOCCOCCO)NC(=O)OCc1ccccc1>>CC(C)(N)CCS(=O)(=O)CCOCCOCCO -US04112086,1,COP(OC)OC.O=C1c2ccccc2C(=O)N1CBr>>COP(=O)(CN1C(=O)c2ccccc2C1=O)OC -US20120108583A1,6,COC(=O)c1cc2nc(Nc3c(Cl)cncc3Cl)sc2c2c1OC(C)(C)C2>>CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(Cl)cncc4Cl)sc23)O1 -US06114390,2,NC(=O)NCc1ccc(CNC(=O)[C@H](N)CCCNC(N)=N[N+](=O)[O-])cc1.O=C(O)c1cccc2[nH]ccc12>>NC(=O)NCc1ccc(CNC(=O)[C@@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)c2cccc3[nH]ccc23)cc1 -US04420555,2,CCCS(=O)(=O)Cl.N#CCC(=O)c1ccc(N)cc1>>CCCS(=O)(=O)Nc1ccc(C(=O)CC#N)cc1 -US20150057265A1,2,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2N)C1.CC(C)(C)OC(=O)Nc1sc2cc(C3CCOCC3)cnc2c1C(=O)O>>CC(C)(C)OC(=O)Nc1sc2cc(C3CCOCC3)cnc2c1C(=O)Nc1cnccc1N1CCC[C@H](NC(=O)OC(C)(C)C)C1 -US20110112120A9,1,CCCc1nc(C)n(-c2ccc(O)c(F)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.CCI>>CCCc1nc(C)n(-c2ccc(OCC)c(F)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US04668660,4,CC(C)(Cc1ccc(Cl)cc1Cl)C(=O)Cn1cncn1.C[S+](C)C>>CC(C)(Cc1ccc(Cl)cc1Cl)C1(Cn2cncn2)CO1 -US08053039B2,7,CCCCCc1ccc(OC(=O)c2ccc([N+](=O)[O-])c(C)c2)cc1>>CCCCCc1ccc(OC(=O)c2ccc(N)c(C)c2)cc1 -US20110039857A1,2,Cc1cccc(-c2sc(C3CC3)nc2C(=O)N2CCC[C@@H](N)C2)c1.Cn1nc(C(=O)O)c2ccccc21>>Cc1cccc(-c2sc(C3CC3)nc2C(=O)N2CCC[C@@H](NC(=O)c3nn(C)c4ccccc34)C2)c1 -US20110172245A1,2,CC(C)(C#N)c1cccc(C(=O)O)c1.Nc1cccc(Oc2ccc([N+](=O)[O-])cc2)c1>>CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Oc3ccc([N+](=O)[O-])cc3)c2)c1 -US06353006B1,3,CCc1cc(C=O)ccc1N=C1SCC2(CCCC2)N1C1CCCC1.N#CCC#N>>CCc1cc(C=C(C#N)C#N)ccc1N=C1SCC2(CCCC2)N1C1CCCC1 -US20140350019A1,3,N#Cc1cc(Br)cc(C(=O)O)c1.OB(O)c1cccc(F)c1>>N#Cc1cc(C(=O)O)cc(-c2cccc(F)c2)c1 -US05304563,6,CCc1cc(CC(=O)OC)ccc1OCc1ccc2ccccc2n1>>CCc1cc(CC(=O)O)ccc1OCc1ccc2ccccc2n1 -US20080255095A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CC(NC)c1cccc(O)c1>>CCOC(=O)CC(c1cccc(O)c1)N(C)C(=O)OC(C)(C)C -US20080146587A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(Br)c2oc(C#N)c(Cc3ccccc3)c2c1>>Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)c2oc(C#N)c(Cc3ccccc3)c2c1 -US20060223801A1,2,CNOC.O=C(O)c1cc(Cl)nc(Cl)c1>>CON(C)C(=O)c1cc(Cl)nc(Cl)c1 -US20070072905A1,7,COc1cc2c(cc1OC)C(=O)C(Cc1ccncc1)C2>>COc1cc2c(cc1OC)C(=O)C(CC1CCNCC1)C2 -US08952185B2,7,O=C(O)Cc1coc2cc(O)ccc12>>O=C(O)C[C@@H]1COc2cc(O)ccc21 -US20120004164A1,2,Cc1nc(N2CCN(Cc3ccc(OC(F)(F)F)cc3)C2=O)sc1C(=O)O.NCC1CC1>>Cc1nc(N2CCN(Cc3ccc(OC(F)(F)F)cc3)C2=O)sc1C(=O)NCC1CC1 -US20050154042A1,3,CCOC(=O)c1c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)cn1C(C)C.CN(C)C=O>>CCOC(=O)c1c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c(C=O)n1C(C)C -US08389527B2,1,N[C@H]1CCCN(Cc2ccccc2)C1.O=C(Nc1ccncc1)c1cnc2c(Nc3ccccn3)cc(Cl)nn12>>O=C(Nc1ccncc1)c1cnc2c(Nc3ccccn3)cc(N[C@H]3CCCN(Cc4ccccc4)C3)nn12 -US20050009895A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc(-c2ccc(CN)c([N+](=O)[O-])c2)no1>>Cc1nc(-c2ccc(CNC(=O)OC(C)(C)C)c([N+](=O)[O-])c2)no1 -US06642228B1,1,CN(C)CCCCl.c1ccc2c(C3CCNCC3)c[nH]c2c1>>CN(C)CCCN1CCC(c2c[nH]c3ccccc23)CC1 -US20070207175A1,7,CCCCCCCC(=O)N(C)Cc1cccc(-c2ccc(C=CC(=O)OCC)cc2)c1>>CCCCCCCC(=O)N(C)Cc1cccc(-c2ccc(CCC(=O)OCC)cc2)c1 -US20080227783A1,7,O=[N+]([O-])c1ccc(Nc2nccs2)cc1>>Nc1ccc(Nc2nccs2)cc1 -US20100216746A1,6,CCOC(=O)c1cc2cccc(NC(=O)OC(C)(C)C)c2[nH]1>>CC(C)(C)OC(=O)Nc1cccc2cc(C(=O)O)[nH]c12 -US20090215822A1,2,O=C(O)c1ccc(F)nc1.c1ccc(-c2nc(C3CCCNC3)no2)nc1>>O=C(c1ccc(F)nc1)N1CCCC(c2noc(-c3ccccn3)n2)C1 -US20120184542A1,6,COc1ncc2cc(C(=O)Nc3cc(C(=O)NCC[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NCC[C@@H](N)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1 -US08623846B2,2,CCO.O=C(O)C1CCC(O)CC1>>CCOC(=O)[C@@H]1CC[C@@H](O)CC1 -US20080004262A1,1,CC1(C)Oc2cc(NS(=O)(=O)CCl)c(O)cc2[C@H](NCCc2ccccc2)[C@H]1O>>CC1(C)Oc2cc3c(cc2[C@H](NCCc2ccccc2)[C@H]1O)OCS(=O)(=O)N3 -US20090181942A1,1,CCOC(=O)/C=C/C(=O)N(Cc1ccc(OC)cc1OC)c1c(Cl)cccc1C(O)c1cccc(OC)c1OC>>CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cccc(Cl)c2N(Cc2ccc(OC)cc2OC)C1=O -US05155268,7,CCCCCCCN(CC)C(=O)Cc1ccc([N+](=O)[O-])cc1>>CCCCCCCN(CC)C(=O)Cc1ccc(N)cc1 -US20090221555A1,1,CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl.COC(=O)NC1CC(C)(C)c2ccc(N)cc2NC1=O>>CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)NC(=O)C(NC(=O)OC)CC3(C)C)ncc1Cl -US05399575,4,N#CCCCCOc1ccc(C=Cc2ccncc2)cc1.[N-]=[N+]=[N-]>>C(=Cc1ccc(OCCCCc2nnn[nH]2)cc1)c1ccncc1 -US20120010402A1,3,C=CCCC(O[Si](C(C)C)(C(C)C)C(C)C)c1ncccc1C=C>>CC(C)[Si](OC1CCC=Cc2cccnc21)(C(C)C)C(C)C -US20040147522A1,6,COC(=O)c1ccc2c(ccn2C)c1>>Cn1ccc2cc(C(=O)O)ccc21 -US20110098288A1,6,CC(C)(C)OC(=O)N1CCCC1CCOc1cccc(Nc2ncc(Cl)c(Nc3ccccc3NS(C)(=O)=O)n2)c1>>CS(=O)(=O)Nc1ccccc1Nc1nc(Nc2cccc(OCCC3CCCN3)c2)ncc1Cl -US20140364433A1,1,Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.Fc1cnc(Cl)nc1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc(F)cn2)c1 -US20060069013A1,1,N#Cc1ccc(CBr)cc1.Oc1ccc(-c2ccccc2)cc1>>N#Cc1ccc(COc2ccc(-c3ccccc3)cc2)cc1 -US20140288069A1,1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NC[C@H](O)c1cccnc1>>O[C@@H](CNc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1cccnc1 -US06387908B1,2,CCOC(=O)[C@H]1O[C@@H]1C(=O)O.CO[C@H](c1ccccc1)[C@@H](N)CC(C)C>>CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)[C@H](OC)c1ccccc1 -US20090221548A1,2,COc1cc(N)ccc1OCCNC(=O)OC(C)(C)C.O=C(O)c1cc(-c2ccc(Cl)cc2)c[nH]1>>COc1cc(NC(=O)c2cc(-c3ccc(Cl)cc3)c[nH]2)ccc1OCCNC(=O)OC(C)(C)C -US09156829B2,6,COc1ccc(COC2CC(NC(=O)OC(C)(C)C)C(NC(=O)c3ccccc3-n3nccn3)C2)cc1>>CC(C)(C)OC(=O)NC1CC(O)CC1NC(=O)c1ccccc1-n1nccn1 -US20110086843A1,2,CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)Cl)s2)s1.CNCCOC>>COCCN(C)S(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)s1 -US20100160308A1,6,CCOC(=O)c1sc(N=[N+]=[N-])nc1-c1ccc(C(F)(F)F)cc1>>[N-]=[N+]=Nc1nc(-c2ccc(C(F)(F)F)cc2)c(C(=O)O)s1 -US04628115,1,CCCc1c(O)ccc(C(C)=O)c1O.CCOC(=O)CCl>>CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1O -US20120094958A1,7,COC(=O)c1ccc2cccc(-c3cccc4ccccc34)c2n1>>OCc1ccc2cccc(-c3cccc4ccccc34)c2n1 -US04371468,2,CC(=O)OC(C)=O.Cc1ncc2n1-c1ccc(N)cc1C(c1ccccc1F)=NC2>>CC(=O)Nc1ccc2c(c1)C(c1ccccc1F)=NCc1cnc(C)n1-2 -US08003785B2,2,CN.Cc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>CNC(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)c(C)c1 -US07135478B2,1,CCOC(=O)c1c(Cl)nc2cc(Cl)c(OC)cc2c1CCl.CN1CCNCC1>>CCOC(=O)c1c(Cl)nc2cc(Cl)c(OC)cc2c1CN1CCN(C)CC1 -US20030216410A1,3,O=C1Cc2cc(Br)ccc2N1.O=Cc1[nH]c(C(=O)NCCCN2CCCC2)c2c1CCCC2>>O=C1Nc2ccc(Br)cc2C1=Cc1[nH]c(C(=O)NCCCN2CCCC2)c2c1CCCC2 -US07579340B2,2,COC(=O)c1sccc1S(=O)(=O)Cl.Nc1ccccc1>>COC(=O)c1sccc1S(=O)(=O)Nc1ccccc1 -US07528163B2,1,CCOC(=O)CBr.COc1ccc2c(C(=O)C(C)(C)C)n[nH]c2c1>>CCOC(=O)Cn1nc(C(=O)C(C)(C)C)c2ccc(OC)cc21 -US07662825B2,1,Nc1nc(Cl)c(Cl)nc1Cl.OCc1cccnc1>>Nc1nc(Cl)c(Cl)nc1OCc1cccnc1 -US04377695,6,CCOC(=O)CCCCCCn1c(=O)oc2ccccc21>>O=C(O)CCCCCCn1c(=O)oc2ccccc21 -US05130119,2,CC1(C)OCC(C(O)CN)O1.O=C(O)c1ccc(S(=O)(=O)Nc2c(F)cc(F)cc2F)cc1>>CC1(C)OCC(C(O)CNC(=O)c2ccc(S(=O)(=O)Nc3c(F)cc(F)cc3F)cc2)O1 -US20070142379A1,3,C=C(C(=C)c1ccc(OC)cc1)c1ccc(OC)cc1.O=C1C=CC(=O)O1>>COc1ccc(C2=C(c3ccc(OC)cc3)CC3C(=O)OC(=O)C3C2)cc1 -US20060270706A1,6,CCOC(=O)CCn1ccc(/C=C2\CN(C(C(=O)OC)c3ccccc3F)CC[C@H]2SC(C)=O)n1>>CCOC(=O)CCn1ccc(/C=C2\CN(C(C(=O)OC)c3ccccc3F)CC[C@H]2S)n1 -US20150038528A1,9,COC(=O)c1nc(I)c2cc(Oc3ccc4ccccc4c3)ccc2c1O.N#C[Cu]>>COC(=O)c1nc(C#N)c2cc(Oc3ccc4ccccc4c3)ccc2c1O -US06465507B2,3,COc1cccc(-c2ccc3c(c2)NC(=O)C3)c1.O=Cc1[nH]cc2c1CCOC2=O>>COc1cccc(-c2ccc3c(c2)NC(=O)C3=Cc2[nH]cc3c2CCOC3=O)c1 -US20110269745A1,6,CC(C)(C)CS(=O)(=O)c1ccc(CNc2c(Cl)ccc3c2CCN(C(=O)C(F)(F)F)CC3)cn1>>CC(C)(C)CS(=O)(=O)c1ccc(CNc2c(Cl)ccc3c2CCNCC3)cn1 -US04912107,7,CCn1c2ccccc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O>>CCn1c2ccccc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3O -US07888352B2,1,O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1.OC1(c2ccccc2)CCNCC1>>OC1(c2ccccc2)CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1 -US05189042,1,CCC1C=C(C)C(F)C(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(N=[N+]=[N-])C(O)C3)C(C)CCC1=O)C(C)CC2OC.CI>>CCC1C=C(C)C(F)C(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(N=[N+]=[N-])C(OC)C3)C(C)CCC1=O)C(C)CC2OC -US20150038438A1,7,Cn1c2c(cc(C(=O)O)c1=O)CC=Cc1cc3c(ccn3C)cc1-2>>Cn1c2c(cc(C(=O)O)c1=O)CCCc1cc3c(ccn3C)cc1-2 -US20130090323A1,3,CC1(C)OB(c2ccc(C(F)F)cc2)OC1(C)C.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1Br>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1ccc(C(F)F)cc1 -US20150182513A1,7,O=C1CCC(Oc2ccc(Br)cc2)CC1>>OC1CCC(Oc2ccc(Br)cc2)CC1 -US20050075293A1,2,CC(NC(=O)OC(C)(C)C)C(=O)O.COC(=O)C(N)Cc1ccc(Oc2ccc(C=C3SC(=O)NC3=O)cc2)cc1>>COC(=O)C(Cc1ccc(Oc2ccc(C=C3SC(=O)NC3=O)cc2)cc1)NC(=O)C(C)NC(=O)OC(C)(C)C -US04125530,2,CS(=O)(=O)Cl.Nc1ccc(-c2nc(C(F)(F)F)c[nH]2)cc1>>CS(=O)(=O)Nc1ccc(-c2nc(C(F)(F)F)c[nH]2)cc1 -US20120172599A1,3,CCCCN(CCCC)c1ccc(C=O)c(OCc2ccccc2)c1.c1ccc([P+](Cc2cccs2)(c2ccccc2)c2ccccc2)cc1>>CCCCN(CCCC)c1ccc(C=Cc2cccs2)c(OCc2ccccc2)c1 -US08519137B2,2,CC(C)(C)c1nnc(C(=O)[O-])s1.Nc1cccc(S(N)(=O)=O)c1>>CC(C)(C)c1nnc(C(=O)Nc2cccc(S(N)(=O)=O)c2)s1 -US20050187266A1,6,CCOC(=O)C1(Cc2ccc(OCCc3ccc(-c4ccc(OC)cc4)cc3)cc2)CCC1>>COc1ccc(-c2ccc(CCOc3ccc(CC4(C(=O)O)CCC4)cc3)cc2)cc1 -US20130245000A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Cl)nc2)CC1.CCOC(=O)Nc1ccc2[nH]ccc2c1>>CCOC(=O)Nc1ccc2c(ccn2-c2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)cn2)c1 -US08178699B2,6,COC(=O)c1sccc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1OC>>COc1cc(C(C)(C)C)ccc1S(=O)(=O)Nc1ccsc1C(=O)O -US06982348B2,6,CCOC(=O)c1cc(C)oc1C(F)(F)F>>Cc1cc(C(=O)O)c(C(F)(F)F)o1 -US05286869,2,COC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc([N+](=O)[O-])c1.OC/C=C/c1cccc(Cc2ncc[nH]2)n1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC/C=C/c2cccc(Cc3ncc[nH]3)n2)C1c1cccc([N+](=O)[O-])c1 -US20150266859A1,1,Clc1c[nH]cn1.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(-n2cnc(Cl)c2)nc1 -US20090197875A1,1,COc1cc(F)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1.c1c[nH]nn1>>COc1cc(-n2ccnn2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1 -US20120323002A1,1,C=C(C)c1cccc(C=O)c1.NNc1cc(N2CCOCC2)c2nc(-c3ccncc3)cn2n1>>C=C(C)c1cccc(C=NNc2cc(N3CCOCC3)c3nc(-c4ccncc4)cn3n2)c1 -US05480858,1,CCO.Cc1cc(Br)c(C)c2c1SCCC2O>>CCOC1CCSc2c(C)cc(Br)c(C)c21 -US06521643B1,7,N#Cc1cccnc1-c1cccc([N+](=O)[O-])c1>>N#Cc1cccnc1-c1cccc(N)c1 -US05089497,7,O=C(CCCN1CCN(c2ccccn2)CC1)c1cccnc1>>c1ccc(N2CCN(CCCCc3cccnc3)CC2)nc1 -US07244747B2,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1c(Br)cc(F)c(N=NN2CCCC2)c1F>>CCOC(=O)C=Cc1c(Br)cc(F)c(N=NN2CCCC2)c1F -US20110263598A1,3,C=Cc1ccncc1.C[Si](C)(C)CCOCn1nc(I)c2ccc([C@@H]3C[C@@]34C(=O)Nc3ccccc34)cc21>>C[Si](C)(C)CCOCn1nc(/C=C/c2ccncc2)c2ccc([C@@H]3C[C@@]34C(=O)Nc3ccccc34)cc21 -US05846728,1,CC(C)(C)OC(=O)NCCCCCC(=O)O.Oc1c(F)c(F)c(F)c(F)c1F>>CC(C)(C)OC(=O)NCCCCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F -US20070003539A1,7,COC(=O)c1cc(OC)ccc1-n1nc(C)cc1C>>COc1ccc(-n2nc(C)cc2C)c(CO)c1 -US20120184542A1,2,N[C@@H](Cc1cccc(F)c1)CN1C(=O)c2ccccc2C1=O.Nc1cc(C(=O)O)ccc1Cl>>Nc1cc(C(=O)N[C@@H](Cc2cccc(F)c2)CN2C(=O)c3ccccc3C2=O)ccc1Cl -US20110086860A1,2,COc1cc(C#CC(=O)O)ccc1-n1cnc(C)c1.NC1c2ccccc2-c2ccccc21>>COc1cc(C#CC(=O)NC2c3ccccc3-c3ccccc32)ccc1-n1cnc(C)c1 -US04952578,2,Nc1ccnn1CCO.O=CO>>O=CNc1ccnn1CCO -US20140303164A1,5,Cn1nc(N)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O[Si](C)(C)C(C)(C)C)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)OC(C)(C)C)c21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cn1nc(NC(=O)C(F)(F)F)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O[Si](C)(C)C(C)(C)C)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)OC(C)(C)C)c21 -US07081140B2,1,NCCCn1ccnc1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(NCCCn2ccnc2)cc1 -US20120077812A1,3,CC(C)OC(=O)N1CCC(COc2ccc(Br)cc2)CC1.O=C(c1ccccc1)c1ccc(B(O)O)cc1>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(C(=O)c4ccccc4)cc3)cc2)CC1 -US20070027112A1,3,CC(=O)Cl.Fc1ccc(-c2ccccc2)cc1>>CC(=O)c1ccc(-c2ccc(F)cc2)cc1 -US20070082912A1,2,Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)O)cc1.NCc1ccncc1>>Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)NCc2ccncc2)cc1 -US20090005353A1,2,CC(C)(C)N1C(=O)C(NC2CCNCC2)=C(c2ccccc2)S1(=O)=O.O=C(Cl)c1ccc(F)c(F)c1>>CC(C)(C)N1C(=O)C(NC2CCN(C(=O)c3ccc(F)c(F)c3)CC2)=C(c2ccccc2)S1(=O)=O -US07348017B2,2,Nc1nc(=S)ss1.O=C(O)Cc1ccc(OCc2ccc(F)cc2)cc1>>O=C(Cc1ccc(OCc2ccc(F)cc2)cc1)Nc1nc(=S)ss1 -US20150259343A1,3,C=O.NCCN1CCC(C2CC2(F)F)c2ccccc21>>FC1(F)CC1C1CCN2CCNCc3cccc1c32 -US20040138223A1,2,COc1ccc(CNc2ccc(OC)cc2)cc1.COc1ccc2c(c1)C(C(=O)O)CCC2>>COc1ccc(CN(C(=O)C2CCCc3ccc(OC)cc32)c2ccc(OC)cc2)cc1 -US20110053897A1,1,CC(C)(C)Nc1nc(Cl)cc2ccn(C[C@@H](O)CO)c(=O)c12.Nc1cnccn1>>CC(C)(C)Nc1nc(Nc2cnccn2)cc2ccn(C[C@@H](O)CO)c(=O)c12 -US20110263571A1,1,COC(=O)c1ccc(Br)cc1N1CCCS1(=O)=O.O=C1NCCO1>>COC(=O)c1ccc(N2CCOC2=O)cc1N1CCCS1(=O)=O -US07030138B2,2,CCOC(=O)Cl.O=[N+]([O-])c1ccc(O)cc1>>CCOC(=O)Oc1ccc([N+](=O)[O-])cc1 -US08586584B2,2,CC(C)(C)OC(=O)NCCCCCCOc1ccc(CNc2nc(Nc3ccc(C(=O)O)cc3)nc(OCC(F)(F)F)n2)cc1.COC(=O)C(N)C1CCCN(C(=O)OC(C)(C)C)C1>>COC(=O)C(NC(=O)c1ccc(Nc2nc(NCc3ccc(OCCCCCCNC(=O)OC(C)(C)C)cc3)nc(OCC(F)(F)F)n2)cc1)C1CCCN(C(=O)OC(C)(C)C)C1 -US20100280024A1,1,CC(C)(C)OC(=O)N1CCC(OCCO)CC1.CI>>COCCOC1CCN(C(=O)OC(C)(C)C)CC1 -US20150011782A1,4,O=C(OO)c1cccc(Cl)c1.OC/C=C/Cc1ccccc1>>OCC1OC1Cc1ccccc1 -US08957070B2,2,CCOC(=O)c1cc2ccc(C)c(N)c2[nH]1.O=S(=O)(Cl)c1cccs1>>CCOC(=O)c1cc2ccc(C)c(NS(=O)(=O)c3cccs3)c2[nH]1 -US05684041,2,CC(C)(C)c1cc(N)cc2c1OCC2(C)C.CCCN=C=O>>CCCNC(=O)Nc1cc(C(C)(C)C)c2c(c1)C(C)(C)CO2 -US20090099231A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc2c(c1F)CCNC2>>CC(C)(C)OC(=O)N1CCc2c(ccc(N)c2F)C1 -US20030078251A1,2,CCOC(=O)CCc1cccc(N)c1.COc1cccc([C@H]2O[C@H](CC(=O)O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC>>CCOC(=O)CCc1cccc(NC(=O)C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)c1 -US06013830,6,CCOC(=O)C(=O)C1CCCCC1>>O=C(O)C(=O)C1CCCCC1 -US04788187,3,CCOP(=O)(CC#N)OCC.COc1ccc(C(C)=O)cc1>>COc1ccc(C(C)=CC#N)cc1 -US05952362,6,Cc1c([N+](=O)[O-])cc(NC(=O)OC(C)(C)C)cc1[N+](=O)[O-]>>Cc1c([N+](=O)[O-])cc(N)cc1[N+](=O)[O-] -US05550129,1,COc1ccc2c(C)c(CCCl)c(=O)oc2c1OC.COc1ccccc1N1CCNCC1>>COc1ccccc1N1CCN(CCc2c(C)c3ccc(OC)c(OC)c3oc2=O)CC1 -US09085578B2,3,Cn1ccc(I)n1.Nc1n[nH]c2c(Br)cn(-c3c(F)cccc3F)c(=O)c12>>Cn1ccc(-c2cn(-c3c(F)cccc3F)c(=O)c3c(N)n[nH]c23)n1 -US20090093454A1,1,CN1CCNCC1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>CN1CCN(c2cccc3nc(CN4CCC[C@H]5CCc6cccnc6[C@H]54)cn23)CC1 -US20090203705A1,3,Nc1cnc(Br)cn1.OB(O)c1ccccc1F>>Nc1cnc(-c2ccccc2F)cn1 -US20100016321A1,1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.Nc1ccc(N2CCCCCC2)cc1>>CC(C)(C)N1C(=O)C(Nc2ccc(N3CCCCCC3)cc2)=C(c2ccccc2)S1(=O)=O -US20010047099A1,6,COC(=O)c1nc(Br)cc(N)c1OC>>COc1c(N)cc(Br)nc1C(=O)O -US20130245042A1,9,[N-]=[N+]=Nc1nccc(NCCCc2ccccc2)c1C(F)(F)F>>Nc1nccc(NCCCc2ccccc2)c1C(F)(F)F -US20150266856A1,7,Cc1ncc(C(C)(C)C#N)c(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>Cc1ncc(C(C)(C)CN)c(C2CCN(C(=O)OC(C)(C)C)CC2)n1 -US08680108B2,7,C#Cc1c(Cl)cc(C(C)=O)c(-c2cccc(F)c2)c1/N=N/N(CC)CC>>C#Cc1c(Cl)cc(C(C)O)c(-c2cccc(F)c2)c1/N=N/N(CC)CC -US20130338157A1,1,C1COCCN1.COc1cc(N2CCN(C(=O)Cn3nc(I)c4cccnc43)CC2)ccc1Cl>>COc1cc(N2CCN(C(=O)Cn3nc(N4CCOCC4)c4cccnc43)CC2)ccc1Cl -US20120196824A1,7,C=Cc1nn(C)c2cc(N(CC(=O)NCCN(CC)C(=O)OC(C)(C)C)CC(=O)N(C)N3Cc4ccccc4C3)c(C)cc12>>CCc1nn(C)c2cc(N(CC(=O)NCCN(CC)C(=O)OC(C)(C)C)CC(=O)N(C)N3Cc4ccccc4C3)c(C)cc12 -US06555584B1,2,CC(C)(C)C(=O)Cl.NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1>>CC(C)(C)C(=O)NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1 -US20110086852A2,6,COc1cc2cc(C(=O)N3CCOCC3)sc2c([N+](=O)[O-])c1O>>O=C(c1cc2cc(O)c(O)c([N+](=O)[O-])c2s1)N1CCOCC1 -US20050059705A1,2,CC(C)(C)C1CCC(N)CC1.COC(=O)c1cc2ccc(C(=O)O)cc2c(CC2CCCC2)n1>>COC(=O)c1cc2ccc(C(=O)NC3CCC(C(C)(C)C)CC3)cc2c(CC2CCCC2)n1 -US20120129843A1,6,CCOC(=O)c1ccc(OCC)c([N+](=O)[O-])c1>>CCOc1ccc(C(=O)O)cc1[N+](=O)[O-] -US20040133008A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(NCCn2nccc2NC(c2ccccc2)(c2ccccc2)c2ccccc2)nc1>>CC(C)(C)OC(=O)N(CCn1nccc1NC(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccc([N+](=O)[O-])cn1 -US06063782,1,Cc1[nH]c2c(OCc3ccc(F)cc3)nncc2c1C.ClC=CCCl>>Cc1c(C)n(CC=CCl)c2c(OCc3ccc(F)cc3)nncc12 -US20090082379A1,1,C1CCNC1.O=Cc1ccc(Br)cn1>>Brc1ccc(CN2CCCC2)nc1 -US06534655B1,7,O=C1c2ccccc2-c2[nH]nc(-c3ccccc3)c21>>OC1c2ccccc2-c2[nH]nc(-c3ccccc3)c21 -US20060229336A1,2,COC(=O)c1cccc(C(=O)O)c1.Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCNCC1>>COC(=O)c1cccc(C(=O)N2CCC(CCN3C4CCC3CC(n3c(C)nc5ccccc53)C4)(c3ccccc3)CC2)c1 -US07745462B2,9,CCCCc1ccc2c(c1)CCC2=O.NO>>CCCCc1ccc2c(c1)CCC2=NO -US20140031338A1,3,CC1(C)OB(c2ccc3c(c2)CCCO3)OC1(C)C.COC(=O)C(OC(C)(C)C)c1cc([N+](=O)[O-])ccc1Cl>>COC(=O)C(OC(C)(C)C)c1cc([N+](=O)[O-])ccc1-c1ccc2c(c1)CCCO2 -US04440929,9,CCOC(=O)c1ncn2c1c(Cl)nc1cc(C(F)(F)F)ccc12.N>>CCOC(=O)c1ncn2c1c(N)nc1cc(C(F)(F)F)ccc12 -US20100137362A1,1,CCNNC(=O)c1nc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl.COC(=O)Cl>>CCN(NC(=O)c1nc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl)C(=O)OC -US20090036493A1,3,O=C1c2ccccc2C(=O)N1Cc1ccc2c(c1)ncn2-c1cccc(Br)c1.OB(O)c1cccnc1>>O=C1c2ccccc2C(=O)N1Cc1ccc2c(c1)ncn2-c1cccc(-c2cccnc2)c1 -US09139589B2,2,CC(=O)Nc1cc(-c2nc(-c3ccccc3Cl)c(N)s2)ccn1.CC(=O)OC(C)=O>>CC(=O)Nc1cc(-c2nc(-c3ccccc3Cl)c(NC(C)=O)s2)ccn1 -US20040224976A1,3,COC(=O)c1ccc2cc(C=O)oc2c1.C[Mg+]>>COC(=O)c1ccc2cc(C(C)O)oc2c1 -US20140329858A1,1,Clc1cc(Cl)cc(I)c1.N#Cc1ccc(N2C(=O)N[C@@H]3CCCC[C@H]32)cc1C(F)(F)F>>N#Cc1ccc(N2C(=O)N(c3cc(Cl)cc(Cl)c3)[C@@H]3CCCC[C@H]32)cc1C(F)(F)F -US20140011777A1,2,CC(=O)Cl.CCOCc1nc2cnc3ccccc3c2n1CC1(O)CCNCC1>>CCOCc1nc2cnc3ccccc3c2n1CC1(O)CCN(C(C)=O)CC1 -US04478837,1,Cc1ccc(C(=O)N2CCc3nnc(NN)cc3C2)cc1.O=C1CCCCC1>>Cc1ccc(C(=O)N2CCc3nnc(NN=C4CCCCC4)cc3C2)cc1 -US20020042524A1,10,COc1ccc(Br)c(C)c1.O=C1CCC(=O)N1Br>>COc1ccc(Br)c(CBr)c1 -US05795887,2,CC(C)N(C(=O)CN1C(=O)C(N)n2cnnc2-c2ccccc21)c1ccccc1.O=C=Nc1ccccc1>>CC(C)N(C(=O)CN1C(=O)C(NC(=O)Nc2ccccc2)n2cnnc2-c2ccccc21)c1ccccc1 -US07745438B2,3,CC(C)(C)OC(=O)N1C[C@H](CCC2CCCCC2)OC[C@@H]1C=O.O=[N+]([O-])CCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@H](CCC2CCCCC2)OC[C@@H]1[C@@H](O)[C@H](Cc1ccccc1)[N+](=O)[O-] -US20090105305A1,2,CC(=O)Cl.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)C1CCNCC1>>CC(=O)N1CCC(S(=O)(=O)Nc2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)ccc2C)CC1 -US08372844B2,1,CC(C)(C)n1nc(CCC=O)cc1-c1ccccc1.Clc1ccc(N2CCNCC2)cc1Cl>>CC(C)(C)n1nc(CCCN2CCN(c3ccc(Cl)c(Cl)c3)CC2)cc1-c1ccccc1 -US20150218181A1,1,CC(C)(O)Cn1cc(-c2ccc3cnc(Cl)cc3c2)cn1.CI>>COC(C)(C)Cn1cc(-c2ccc3cnc(Cl)cc3c2)cn1 -US07851473B2,2,Fc1ccc(-c2csc(N3CCNCC3)n2)cc1.O=C(Nc1cccnc1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnc1)N1CCN(c2nc(-c3ccc(F)cc3)cs2)CC1 -US20140121187A1,6,COc1cc(C(C)C)ccc1C1(O)C(=O)c2ccc(N)c(NC(C)=O)c2C1=O>>COc1cc(C(C)C)ccc1C1(O)C(=O)c2ccc(N)c(N)c2C1=O -US20060074102A1,2,Nc1ccc(-c2cncc3sc(-c4nn[nH]n4)cc23)cc1.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(-c2cncc3sc(-c4nn[nH]n4)cc23)cc1)c1cccc(C(F)(F)F)c1 -US20070027184A1,1,CC(=O)c1ccc(NS(=O)(=O)c2ccc3nc(Cl)ccc3c2)nc1.CN1CCNCC1>>CC(=O)c1ccc(NS(=O)(=O)c2ccc3nc(N4CCN(C)CC4)ccc3c2)nc1 -US08937092B2,2,CC(C(=O)O)c1ccc(C#N)cc1.Cc1cccc(-c2nc(C(F)(F)F)ccc2CN)c1>>Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(C#N)cc2)c1 -US20070049581A1,2,CCOC(=O)CCCN1CCC(N2CCNCC2)CC1.Nc1c(Cl)cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc1C(F)(F)F>>CCOC(=O)CCCN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(Cl)c(N)c(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1 -US20150266822A1,2,COCc1cc(C(=O)O)cc(-c2ccc(C)cn2)c1.Cc1ncc([C@@H](C)N)cn1>>COCc1cc(C(=O)N[C@H](C)c2cnc(C)nc2)cc(-c2ccc(C)cn2)c1 -US07687522B2,3,COc1ccc(B(O)O)cc1F.CSc1ncc(Br)c(=O)n1Cc1ccccc1>>COc1ccc(-c2cnc(SC)n(Cc3ccccc3)c2=O)cc1F -US20140107109A1,3,C[Mg+].O=Cc1cc(Br)cnc1F>>CC(O)c1cc(Br)cnc1F -US20060160864A1,2,CCCCOCCOc1ccc(-c2ccc(N3CCCCCC3)c(/C=C(\CC)C(=O)O)c2)cc1.CCCn1cncc1C[S@](=O)c1ccc(N)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCCCCC3)c(/C=C(\CC)C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1 -US20090274650A1,2,CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(OCCCN)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2.O=C(O)c1ccoc1>>CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(OCCCNC(=O)c2ccoc2)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2 -US07504508B2,1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(O)cc2)c2ccccc21.O=C1CCCN1CCCO>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCCN3CCCC3=O)cc2)c2ccccc21 -US20090181942A1,6,CCOC(=O)C[C@@H]1O[C@@H](c2cccc(OC)c2OC)c2cc(C#N)ccc2-n2c1nnc2C(F)(F)F>>COc1cccc([C@@H]2O[C@@H](CC(=O)O)c3nnc(C(F)(F)F)n3-c3ccc(C#N)cc32)c1OC -US07560558B2,1,COc1cc2nccc(Cl)c2cc1OC.Cc1ccc(O)c([N+](=O)[O-])n1>>COc1cc2nccc(Oc3ccc(C)nc3[N+](=O)[O-])c2cc1OC -US20090270359A1,2,COC(=O)c1ccc(Cn2nc(C)c(-c3ccc(C#N)c(Cl)c3)c2C)cn1.NN>>Cc1nn(Cc2ccc(C(=O)NN)nc2)c(C)c1-c1ccc(C#N)c(Cl)c1 -US20150011508A1,2,Cc1ccc(-c2noc(CN)n2)cc1NC(=O)c1cnc2ccccn12.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1ccc(-c2noc(CNC(=O)Oc3ccc([N+](=O)[O-])cc3)n2)cc1NC(=O)c1cnc2ccccn12 -US20100016327A1,7,O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1O>>Oc1c(Cc2ccccc2)cnc2c(C(F)(F)F)cccc12 -US08669271B2,3,CC(C)(C)OC(=O)N1CCC(C2Cc3cc(B4OC(C)(C)C(C)(C)O4)ccc3O2)CC1.N#Cc1cnccc1Br>>CC(C)(C)OC(=O)N1CCC(C2Cc3cc(-c4ccncc4C#N)ccc3O2)CC1 -US05472958,1,CC(C)(C)OC(=O)N1CC[C@@H]1CO.O=[N+]([O-])c1cccc(O)c1>>CC(C)(C)OC(=O)N1CC[C@H]1COc1cccc([N+](=O)[O-])c1 -US20090182029A1,2,Cc1[nH]c(C=NN=C2C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NCCCCCC(=O)O.Nc1ccc(Cl)cc1N>>Cc1[nH]c(C=NN=C2C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NCCCCCC(=O)Nc1ccc(Cl)cc1N -US04812164,1,C#CCBr.CCOc1nc(C(F)(F)F)cc(=O)n1-c1cc(O)c(Cl)cc1F>>C#CCOc1cc(-n2c(OCC)nc(C(F)(F)F)cc2=O)c(F)cc1Cl -US20120122843A1,3,CON(C)C(=O)CCl.Fc1ccc(Br)nc1>>O=C(CCl)c1ccc(F)cn1 -US20080221188A1,1,CC(=O)c1ccc(C(C)(C)C#N)c(C)c1.N>>Cc1cc(C(C)N)ccc1C(C)(C)C#N -US04867781,1,CI.O=S1(=O)NCc2cccc(Cl)c21>>CN1Cc2cccc(Cl)c2S1(=O)=O -US20140336175A1,1,Nc1nc(F)nc2c1ncn2C1CCCCO1.OC1CCCCC1>>Nc1nc(OC2CCCCC2)nc2c1ncn2C1CCCCO1 -US07378417B2,2,CCNS(=O)(=O)c1cccc(N)c1.CCOc1cc(-c2cc(C(F)(F)F)n3ncc(C(=O)O)c3n2)ccc1C(F)(F)F>>CCNS(=O)(=O)c1cccc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)c(OCC)c4)nc23)c1 -US20080200475A1,2,CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(N)nc2s1.COC(=O)CCC(=O)Cl>>CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(NC(=O)CCC(=O)OC)nc2s1 -US20120258993A1,7,COC(=O)c1cc(OC)cc(C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)c1>>COc1cc(CO)cc(C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)c1 -US04673671,1,COc1ccc(C=O)c(Cl)c1O.ClCc1ccccc1>>COc1ccc(C=O)c(Cl)c1OCc1ccccc1 -US05929074,1,CCOC(=O)CBr.COc1ccc(CNC(=O)OCc2ccccc2)cc1O>>CCOC(=O)COc1cc(CNC(=O)OCc2ccccc2)ccc1OC -US08729271B2,2,Cn1cnc(C(=O)O)c1.FC(F)(F)Oc1ccc(-c2nc(CNC3CCC3)cs2)cc1>>Cn1cnc(C(=O)N(Cc2csc(-c3ccc(OC(F)(F)F)cc3)n2)C2CCC2)c1 -US20100036118A1,2,CN(C)C(=O)c1cc(Br)ccc1N.O=C(Cl)N1CCOCC1>>CN(C)C(=O)c1cc(Br)ccc1NC(=O)N1CCOCC1 -US05538976,1,BrCc1ccc(Br)cc1.N#Cc1ccc(Nc2cccnn2)cc1>>N#Cc1ccc(N(Cc2ccc(Br)cc2)c2cccnn2)cc1 -US08642576B2,8,OC(c1ccc(F)c(Br)c1)c1ccc(F)cc1OC(F)(F)C(F)F>>O=C(c1ccc(F)c(Br)c1)c1ccc(F)cc1OC(F)(F)C(F)F -US20040006229A1,7,Cc1csc2ccc(C3=CCNC(C)C3)cc12>>Cc1csc2ccc(C3CCNC(C)C3)cc12 -US20140080801A1,2,CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)O.Nc1cnn(CC(F)F)c1N1CCC(F)C(NC(=O)C(F)(F)F)CC1>>CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnn(CC(F)F)c1N1CCC(F)C(NC(=O)C(F)(F)F)CC1 -US20030050330A1,1,CO.Cc1ccc(Cl)c(O)c1>>COc1cc(C)ccc1Cl -US20050267133A1,2,CS(=O)(=O)CCN.O=C(O)c1ccc(/C=N/Nc2ncnc3c2cnn3-c2ccccc2)cc1>>CS(=O)(=O)CCNC(=O)c1ccc(/C=N/Nc2ncnc3c2cnn3-c2ccccc2)cc1 -US20130045975A1,1,CNCCCO.COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)[nH]c2c1OCCCCCCCl>>COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)[nH]c2c1OCCCCCCN(C)CCCO -US20120329818A1,6,CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cccc(-c3nnn[nH]3)c2)CC1>>CC1(C(=O)Nc2cccc(-c3nnn[nH]3)c2)CCNCC1 -US20140336377A1,2,NCc1cnc(OCC(F)(F)F)c(Cl)c1.Nc1nccc(C(=O)O)n1>>Nc1nccc(C(=O)NCc2cnc(OCC(F)(F)F)c(Cl)c2)n1 -US20130178459A1,3,CC(C)(C)OC(=O)NCC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CCC1.COc1cc(C)c2[nH]c(=O)c3sccc3c2c1Br>>COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc(C2(CNC(=O)OC(C)(C)C)CCC2)cc1 -US04892873,1,CC(=O)Nc1cccc(-c2ccc(Cl)nn2)c1.CCI>>CCN(C(C)=O)c1cccc(-c2ccc(Cl)nn2)c1 -US20080293940A1,2,CN1CCN(Cc2ccc(C(=O)Cl)cc2C(F)(F)F)CC1.Cc1ccc(N)cc1N>>Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1N -US04833152,6,CC(=O)SCC(C)C(=O)N[C@H](C(=O)O)C(C)C>>CC(CS)C(=O)N[C@H](C(=O)O)C(C)C -US20090099187A1,2,CCOC(=O)Cl.COc1ccc(S(=O)(=O)Nc2ccccc2)c2c1C[C@@H](N)CC2>>CCOC(=O)N[C@H]1CCc2c(S(=O)(=O)Nc3ccccc3)ccc(OC)c2C1 -US20040152714A1,1,COc1cc(CCl)ccc1OCc1ccccc1.Cc1nc(C)c(Cl)c(N)n1>>COc1cc(CNc2nc(C)nc(C)c2Cl)ccc1OCc1ccccc1 -US05177087,1,C1CCNC1.CC(=O)N1CCC(CCC(=O)c2ccc(F)cc2)CC1>>CC(=O)N1CCC(CCC(=O)c2ccc(N3CCCC3)cc2)CC1 -US04024273,6,COc1ccc(C(=O)c2c(-c3ccc(Cl)cc3)oc3ccccc23)cc1>>O=C(c1ccc(O)cc1)c1c(-c2ccc(Cl)cc2)oc2ccccc12 -US20130004420A1,1,C=CCNCC=C.COCOC(c1cc(CBr)ccc1I)(C(F)(F)F)C(F)(F)F>>C=CCN(CC=C)Cc1ccc(I)c(C(OCOC)(C(F)(F)F)C(F)(F)F)c1 -US08609848B2,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OC.COc1ccc2ccccc2c1C(=O)O>>COc1ccc(C2=NN(C3CCN(C(=O)c4c(OC)ccc5ccccc45)CC3)C(=O)C2(C)C)cc1OC -US20090221555A1,1,CC(=O)N1CCC(=O)NCc2cc(N)ccc21.CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl>>CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)CNC(=O)CCN3C(C)=O)ncc1Cl -US04382937,1,C=Cn1cc(C(=O)OCC)c(=O)c2cc(F)c(Cl)nc21.O=C(NC1CCNC1)C(F)(F)F>>C=Cn1cc(C(=O)OCC)c(=O)c2cc(F)c(N3CCC(NC(=O)C(F)(F)F)C3)nc21 -US20030199440A1,1,Brc1cccc(Br)n1.CC[O-]>>CCOc1cccc(Br)n1 -US07745641B2,2,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccccc3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21 -US20010047031A1,8,O=S([O-])OO.Oc1ccc(SC2CCN(CCCCc3ccccc3)C2)cc1>>O=S(c1ccc(O)cc1)C1CCN(CCCCc2ccccc2)C1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)NC(C)C)cc1Br>>Cc1ccc(S(=O)(=O)NC(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C -US20140024650A1,1,CC(C)(C)OC(=O)N[C@@H]1CCOC[C@H]1CO.Cc1cnn(-c2ccc(O)cc2)c1>>Cc1cnn(-c2ccc(OC[C@@H]3COCC[C@H]3NC(=O)OC(C)(C)C)cc2)c1 -US20120232049A1,9,NC(=O)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1>>Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1 -US04835275,7,O=C1CCCc2nc3ccccc3c(NCCCC(c3ccc(F)cc3)c3ccc(F)cc3)c21>>OC1CCCc2nc3ccccc3c(NCCCC(c3ccc(F)cc3)c3ccc(F)cc3)c21 -US20120108583A1,2,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1.NCc1ccccc1C(F)(F)F>>CC1(C)Cc2c(c(C(=O)NCc3ccccc3C(F)(F)F)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1 -US20120214767A1,3,CC(C)(C=O)c1ccc(Cl)cc1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=CC(C)(C)c1ccc(Cl)cc1 -US06838463B2,1,C#CCOc1cc(Cl)ncn1.Oc1ccc(Cl)cc1>>C#CCOc1cc(Oc2ccc(Cl)cc2)ncn1 -US05559125,7,C=Cc1cc(Cl)cc(N)c1C(=O)OC>>CCc1cc(Cl)cc(N)c1C(=O)OC -US20040110775A1,7,CC(=O)c1ccc([N+](=O)[O-])cc1>>CC(=O)c1ccc(N)cc1 -US20130158075A1,6,COC(=O)C(C)(C)CCc1ncc(-c2ccc(NC(=O)NCCN3CCCCC3)cc2)s1>>CC(C)(CCc1ncc(-c2ccc(NC(=O)NCCN3CCCCC3)cc2)s1)C(=O)O -US20070259851A1,7,O=[N+]([O-])c1c(F)cccc1CCNC1CCN(Cc2ccccc2)CC1>>Nc1c(F)cccc1CCNC1CCN(Cc2ccccc2)CC1 -US07598264B2,6,CCOC(=O)c1ncc(O)c2c1CCN(Cc1ccc(F)c(Cl)c1)C2=O>>O=C(O)c1ncc(O)c2c1CCN(Cc1ccc(F)c(Cl)c1)C2=O -US20090075980A1,2,COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)N.O=C(Cl)c1ccc(F)c(F)c1>>COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)NC(=O)c1ccc(F)c(F)c1 -US20100075952A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2.O=C1Cc2cc(F)ccc2N1>>Cc1c(C=C2C(=O)Nc3ccc(F)cc32)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2 -US20140135320A1,3,COCOc1c(C=O)cc(C(C)(C)C)cc1-c1ccc(C(F)(F)F)nc1.C[Mg+]>>COCOc1c(-c2ccc(C(F)(F)F)nc2)cc(C(C)(C)C)cc1C(C)O -US20060160802A1,6,CCCCC1CC(C=NOCc2ccccc2)(C(=O)OC)C1>>CCCCC1CC(C=NOCc2ccccc2)(C(=O)O)C1 -USRE040558E1,1,COC(=O)c1c(C)cccc1CBr.OCCCCNc1ccc2ccccc2n1>>COC(=O)c1c(C)cccc1COCCCCNc1ccc2ccccc2n1 -US20110077248A1,6,CCOC(=O)c1cccn2cc(-c3ccc(C(F)F)cc3)nc12>>O=C(O)c1cccn2cc(-c3ccc(C(F)F)cc3)nc12 -US20020160983A1,4,CC(=O)O.COc1ccc2c(=O)cc(-c3ccc(N)c(N)c3)oc2c1OC>>COc1ccc2c(=O)cc(-c3ccc4[nH]c(C)nc4c3)oc2c1OC -US05292452,3,CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C[C@@H]1CC[C@@H](c2ccc(-c3ccc(F)c(F)c3)cc2)CC1>>CC=C[C@@H]1CC[C@@H](c2ccc(-c3ccc(F)c(F)c3)cc2)CC1 -US20060142318A1,1,CCOC(=O)CBr.NCCCN(Cc1ccccc1)C[C@H]1COc2cccnc2O1>>CCOC(=O)CNCCCN(Cc1ccccc1)C[C@H]1COc2cccnc2O1 -US06413995B1,6,CCOC(=O)CC(O)(c1ccccc1)c1ccc(OCOC)cc1>>COCOc1ccc(C(O)(CC(=O)O)c2ccccc2)cc1 -US08143271B2,2,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(C(=O)O)cc23)c1F.CCN>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(C(=O)NCC)cc23)c1F -US04147659,1,CCCCCCCCCCCCOc1nc(Cl)nc(OCCCCCCCCCCCC)n1.Oc1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1>>CCCCCCCCCCCCOc1nc(OCCCCCCCCCCCC)nc(Oc2cc(-c3ccccc3)c(O)c(-c3ccccc3)c2)n1 -US20040002506A1,2,COC(=O)CCCCCCC(=O)C(F)(F)F.Nc1ccccc1>>O=C(CCCCCCC(=O)C(F)(F)F)Nc1ccccc1 -US20130005707A1,1,Cn1ncc2cc(Br)cnc21.N=C(c1ccccc1)c1ccccc1>>Cn1ncc2cc(N=C(c3ccccc3)c3ccccc3)cnc21 -US07115762B2,3,C=CC(=O)OC.Ic1ccccc1>>COC(=O)/C=C/c1ccccc1 -US20030229096A1,3,COc1cnnc(Cl)c1.OB(O)c1ccc(F)c(Cl)c1>>COc1cnnc(-c2ccc(F)c(Cl)c2)c1 -US20080085273A1,7,CCOC(=O)CCCCc1ccncc1>>OCCCCCc1ccncc1 -US20090198063A1,6,CC(=O)OCc1cc(OCCNC(=O)OC(C)(C)C)c(OCc2ccccc2)cn1>>CC(=O)OCc1cc(OCCNC(=O)OC(C)(C)C)c(O)cn1 -US08575160B2,3,CC1(C)C(=O)c2cncn2[C@H]1c1ccc(C#N)cc1F.Fc1ccc([Mg+])cc1>>CC1(C)[C@H](c2ccc(C#N)cc2F)n2cncc2[C@@]1(O)c1ccc(F)cc1 -US08466181B2,2,Cn1nnc(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)O)cn2)cn1.NN1CCOCC1>>Cn1nnc(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)NN3CCOCC3)cn2)cn1 -US04410539,7,Cc1sc2cc(C(=O)O)ccc2c1Br>>Cc1sc2cc(CO)ccc2c1Br -US20070149525A1,2,CC(C)(C)C(=O)CN.CC(C)(C)OC(=O)NC1(C(=O)O)CC1>>CC(C)(C)OC(=O)NC1(C(=O)NCC(=O)C(C)(C)C)CC1 -US20100055071A1,3,CC1(C)OB(c2cccc(C(=O)NC3CC3)c2)OC1(C)C.O=C(OCc1ccccc1)N1CCCC1c1ccc(Br)cc1>>O=C(NC1CC1)c1cccc(-c2ccc(C3CCCN3C(=O)OCc3ccccc3)cc2)c1 -US20050107444A1,1,FC(F)(F)c1cccc(CNCC(c2ccccc2)c2ccccc2)c1Cl.OCCCBr>>OCCCN(Cc1cccc(C(F)(F)F)c1Cl)CC(c1ccccc1)c1ccccc1 -US09056865B2,6,Cc1cnc(-c2nc(N3CCC(NC(=O)OC(C)(C)C)CC3)ccc2Cl)c(C)c1>>Cc1cnc(-c2nc(N3CCC(N)CC3)ccc2Cl)c(C)c1 -US08071650B2,2,COc1ccc2c(c1)CCCC2N.S=C=NCc1ccc(Cl)cc1>>COc1ccc2c(c1)CCCC2NC(=S)NCc1ccc(Cl)cc1 -US04233318,2,CCCCCCCN=C=S.NCc1ccccc1>>CCCCCCCNC(=S)NCc1ccccc1 -US08084448B2,6,O=C1CN(c2ccc(-c3cn[nH]c3)cc2OCc2ccccc2)S(=O)(=O)N1>>O=C1CN(c2ccc(-c3cn[nH]c3)cc2O)S(=O)(=O)N1 -US20150152096A1,1,CCOC(=O)C1=C(CBr)NC(c2nccs2)=NC1c1ccc(Cl)cc1Cl.O=C(O)CC1CNCCO1>>CCOC(=O)C1=C(CN2CCOC(CC(=O)O)C2)NC(c2nccs2)=NC1c1ccc(Cl)cc1Cl -US07122545B2,2,COCC(=O)Cl.COc1ccc(N2CCOCC2)c2sc(-c3nc4c([nH]3)CCNCC4)nc12>>COCC(=O)N1CCc2nc(-c3nc4c(OC)ccc(N5CCOCC5)c4s3)[nH]c2CC1 -US04757069,6,CC(=O)O[C@H](CCc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@H](O)CCc1ccc([N+](=O)[O-])cc1 -US20040049079A1,9,CN[C@@H](C)[C@H](O)c1ccccc1>>CN[C@@H](C)Cc1ccccc1 -US20120208815A1,2,Nc1cnccc1N1CCCCC1.Nc1nc(N)c(C(=O)O)nc1Cl>>Nc1nc(N)c(C(=O)Nc2cnccc2N2CCCCC2)nc1Cl -US20090023731A1,2,Nc1cccc(OCCCN2CCOCC2)c1.O=C=Nc1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)Nc1cccc(OCCCN2CCOCC2)c1 -US05242914,1,CCI.CNC(=O)[C@@H]1C[C@H](SCc2ccc(OC)cc2)CN1>>CCN1C[C@@H](SCc2ccc(OC)cc2)C[C@H]1C(=O)NC -US06156758,6,COc1cc2nc(N3CCC(Nc4ccc(C(=O)OC(C)(C)C)cc4)CC3)nc(Nc3ccc(C)cc3)c2cc1OC>>COc1cc2nc(N3CCC(Nc4ccc(C(=O)O)cc4)CC3)nc(Nc3ccc(C)cc3)c2cc1OC -US20090286778A1,2,O=C(C[C@H]1CCCNC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2.O=C=Nc1ccccc1>>O=C(C[C@H]1CCCN(C(=O)Nc2ccccc2)C1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2 -US20040167127A1,2,CCN=C=O.Oc1ccc(-c2nn(C3CCCC3)c3c(F)cccc23)cc1>>CCNC(=O)Oc1ccc(-c2nn(C3CCCC3)c3c(F)cccc23)cc1 -US05604218,1,O=[N+]([O-])c1cccnc1Cl.c1cn[nH]c1>>O=[N+]([O-])c1cccnc1-n1cccn1 -US20060069132A1,7,CCNC(=O)c1cc([N+](=O)[O-])ccc1F>>CCNC(=O)c1cc(N)ccc1F -US08084449B2,1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(Cl)c(-c3cccc(C=O)c3)c2)n1.CN1CCNCC1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(Cl)c(-c3cccc(CN4CCN(C)CC4)c3)c2)n1 -US07229987B2,2,CN(C)CCCN.O=C(O)c1ccc(-c2nnc(COCCCc3ccccc3)o2)cc1>>CN(C)CCCNC(=O)c1ccc(-c2nnc(COCCCc3ccccc3)o2)cc1 -US20090221555A1,1,CCN1C(=O)CCC(C)(C)c2ccc(N)cc21.CCNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl>>CCNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)N(CC)C(=O)CCC3(C)C)ncc1Cl -US20070010520A1,9,Brc1cn2nc(-c3ccco3)nc2c(Br)n1.N>>Nc1nc(Br)cn2nc(-c3ccco3)nc12 -US20130109682A1,1,CC1OC(c2ccncc2[N+](=O)[O-])CC(=O)C1O.NCc1ccccc1>>CC1OC(c2ccncc2[N+](=O)[O-])CC(NCc2ccccc2)C1O -US07728005B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H](O)CN>>C[C@@H](O)CNC(=O)OC(C)(C)C -US20150025073A1,6,COC(=O)C1CN(Cc2ccccc2)CC2(CCN(C(=O)OC(C)(C)C)CC2)O1>>COC(=O)C1CNCC2(CCN(C(=O)OC(C)(C)C)CC2)O1 -US07754886B2,7,COC(=O)[C@H](CSc1ccccc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC(CO)CSc1ccccc1 -US20100130446A1,4,O=C(CCC(=O)C(CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1)c1ccccn1.[NH4+]>>O=S(=O)(c1ccc(C(CC2CCOCC2)c2ccc(-c3ccccn3)[nH]2)cc1)C1CC1 -US20110046104A1,1,F[C@H]1CCNC1.O=C(CC(F)(F)F)Nc1ccc(Sc2nc(Cl)cc(Nc3ccccn3)n2)cc1>>O=C(CC(F)(F)F)Nc1ccc(Sc2nc(Nc3ccccn3)cc(N3CC[C@H](F)C3)n2)cc1 -US05854237,7,O=C(c1ccc([N+](=O)[O-])cc1)N1Cc2cccn2Cc2ccccc21>>Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 -US07265123B2,7,CC(C)S(=O)(=O)CC#N>>CC(C)S(=O)(=O)CCN -US07820707B2,1,CNC(=O)c1c(NC(=O)CCCl)sc2c1CCCC2.O=Cc1c[nH]nc1C(F)(F)F>>CNC(=O)c1c(NC(=O)CCn2cc(C=O)c(C(F)(F)F)n2)sc2c1CCCC2 -US20080306109A1,6,CCOC(=O)Cc1c(C)c(Sc2ccc(S(C)(=O)=O)cc2Cl)c2cc(C#N)ccn12>>Cc1c(Sc2ccc(S(C)(=O)=O)cc2Cl)c2cc(C#N)ccn2c1CC(=O)O -US20140303186A1,2,CCOC(=O)Cc1nn(Cc2ccc(N)cc2)c2ccccc12.N#Cc1ccc(C(=O)Cl)cc1>>CCOC(=O)Cc1nn(Cc2ccc(NC(=O)c3ccc(C#N)cc3)cc2)c2ccccc12 -US20100261727A1,1,CN.Clc1ccnc(Cl)n1>>CNc1ccnc(Cl)n1 -US04307233,1,C=[N+]=[N-].CC1=C(C(=O)O)N2C(=O)C(NC(=O)OC(C)(C)C)C2SC1>>COC(=O)C1=C(C)CSC2C(NC(=O)OC(C)(C)C)C(=O)N12 -US20100093705A1,1,CCI.O=Cc1cccc2[nH]ccc12>>CCn1ccc2c(C=O)cccc21 -US20110136801A1,6,CCOC(=O)C(C)(C)Oc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)CCN(C)C)c1>>COCCc1nc2c(N)nc3ccccc3c2n1CCCCN(CCN(C)C)Cc1cccc(OC(C)(C)C(=O)O)c1 -US20130274260A1,3,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CCl)c1.OB(O)c1ccccc1C(F)(F)F>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccccc2C(F)(F)F)c1 -US04745117,1,BrCCCCBr.O=C1NS(=O)(=O)c2ccccc21>>O=C1c2ccccc2S(=O)(=O)N1CCCCBr -US20110118116A1,3,C#CCC(NC(=O)OC(C)(C)C)c1cccc(C)c1C.Cc1cccc(I)c1>>Cc1cccc(C#CCC(NC(=O)OC(C)(C)C)c2cccc(C)c2C)c1 -US20020048588A1,2,CCCCCCCCCCC[C@H](CC(=O)O)OC(=O)CCCCCCCCC.N[C@H](CO)C(=O)OCc1ccccc1>>CCCCCCCCCCC[C@H](CC(=O)N[C@H](CO)C(=O)OCc1ccccc1)OC(=O)CCCCCCCCC -US20080287466A1,2,CC(C)(C)N=C=O.NC1=c2ccoc2=NCN1c1cccc(N)c1>>CC(C)(C)NC(=O)Nc1cccc(N2CN=c3occc3=C2N)c1 -US06521666B1,6,COC(=O)[C@H](Cc1ccc(-c2ccccc2OC)cc1)NC(=O)c1ccc(C(=O)OC(C)(C)C)cc1Cl>>COC(=O)[C@H](Cc1ccc(-c2ccccc2OC)cc1)NC(=O)c1ccc(C(=O)O)cc1Cl -US20100273779A1,6,CCOC(=O)CC(C)C(=O)c1ccc(OC)cc1>>CCOC(=O)CC(C)C(=O)c1ccc(O)cc1 -US05192766,2,COc1cc(CN2CCNCC2)cc(OC)c1OC.O=C(O)C=Cc1cccc(-c2ccccc2)c1>>COc1cc(CN2CCN(C(=O)C=Cc3cccc(-c4ccccc4)c3)CC2)cc(OC)c1OC -US06143764,6,COc1cc2nccc(Oc3ccc(NC(=O)c4ccc(OC(C)=O)cc4)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)c4ccc(O)cc4)cc3)c2cc1OC -US05985869,7,CC(=O)Oc1cccc(C(=O)Nc2ccc(C(=O)N3CCCc4ccccc43)cc2)c1>>O=C(Nc1ccc(C(=O)N2CCCc3ccccc32)cc1)c1cccc(O)c1 -US07989446B2,3,C#CCCC(=O)N1CCN(C)CC1.OCc1cccc(Br)n1>>CN1CCN(C(=O)CCC#Cc2cccc(CO)n2)CC1 -US04425340,2,Nc1nc(C(=NOC(CCO)C(=O)O)C(=O)O)ns1>>Nc1nc(C(=NOC2CCOC2=O)C(=O)O)ns1 -US20080194629A1,2,COCCOCC1(CNC(=O)[C@H]2C[C@@H](N)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)c2ccccc2Oc2ccccc21.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>COCCOCC1(CNC(=O)[C@H]2C[C@@H](NS(=O)(=O)c3ccc(C(F)(F)F)cc3)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)c2ccccc2Oc2ccccc21 -US04009129,10,C=CC1OCC(CCCCO)O1.ClCl>>OCCCCC1COC(C(Cl)CCl)O1 -US08518939B2,7,C[C@H](c1ccccc1)N1C[C@H](c2ccc(Br)cc2)OCC1=O>>C[C@H](c1ccccc1)N1CCO[C@@H](c2ccc(Br)cc2)C1 -US06825354B2,1,CC#CCBr.Oc1ccc(O)cc1>>CC#CCOc1ccc(O)cc1 -US20150191439A1,1,COc1ccccc1-c1nc(CCl)no1.NC12CC3CC(CC(C3)C1)C2>>COc1ccccc1-c1nc(CNC23CC4CC(CC(C4)C2)C3)no1 -US20090221555A1,7,COc1ccc2c(c1)CC(=O)NCC2>>COc1ccc2c(c1)CCNCC2 -US07776875B2,9,CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)O.N>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(N)=O -US20120029190A1,4,O=C(OCc1ccccc1)N1CC=CCCC1.O=C(OO)c1cccc(Cl)c1>>O=C(OCc1ccccc1)N1CCCC2OC2C1 -US20060287315A1,7,O=C1N(CCO)CCCN1c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2CCCN(CCO)C2=O)cc1 -US06713474B2,1,CCNCC.O=Cc1ccccc1Oc1ccc(-c2cn(C3CCOC3)c3ncnc(Cl)c23)cc1>>CCN(CC)Cc1ccccc1Oc1ccc(-c2cn(C3CCOC3)c3ncnc(Cl)c23)cc1 -US20100105607A1,1,BrCCCOc1ccccc1.C[O-]>>COCCCOc1ccccc1 -US20110269965A1,9,CCc1nc(C#N)c(N)n1CCCCNS(C)(=O)=O.ICI>>CCc1nc(C#N)c(I)n1CCCCNS(C)(=O)=O -US20130150326A1,1,COC(=O)c1cccc(Sc2c(C)[nH]c3cc(Cl)ccc23)c1.Cc1ccc(Br)cn1>>COC(=O)c1cccc(Sc2c(C)n(-c3ccc(C)nc3)c3cc(Cl)ccc23)c1 -US20050124683A1,7,O=C(O)c1cccc2[nH]ccc12>>O=C(O)c1cccc2c1CCN2 -US06127414,6,C[C@@H](NC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)c1cccc2ccccc12>>C[C@@H](NC(=O)[C@H](N)CCCNC(=O)OCc1ccccc1)c1cccc2ccccc12 -US20060247226A1,2,CC(C)=CCn1c(N2CCCC(NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(CC(=O)c1cccc(N)c1)c(=O)n2C.COC(=O)Cl>>COC(=O)Nc1cccc(C(=O)Cn2c(=O)c3c(nc(N4CCCC(NC(=O)OC(C)(C)C)C4)n3CC=C(C)C)n(C)c2=O)c1 -US20050107339A1,7,CC=C(c1cc(OC)cc(OC)c1)c1ccc(OC)c([N+](=O)[O-])c1>>CC=C(c1cc(OC)cc(OC)c1)c1ccc(OC)c(N)c1 -US20070270460A1,3,COc1cc2c(cc1OC)C(Cc1ccc(Br)cc1)NCC2.COc1cccc(B(O)O)c1>>COc1cccc(-c2ccc(CC3NCCc4cc(OC)c(OC)cc43)cc2)c1 -US20080280855A1,7,Cc1ccccc1C(=O)CCc1c(C(=O)N(C)C)cc2c(nc(C)n2C)c1O>>Cc1ccccc1[C@H](O)CCc1c(C(=O)N(C)C)cc2c(nc(C)n2C)c1O -US07375099B2,2,CN1C(=O)C(N)c2ccccc2-c2ccccc21.O=C(O)C(F)C(=O)NCc1cc(F)cc(F)c1>>CN1C(=O)C(NC(=O)C(F)C(=O)NCc2cc(F)cc(F)c2)c2ccccc2-c2ccccc21 -US09073882B2,1,COc1cc(CC=O)ccc1C#N.Cc1c(CCN2CCNCC2)ccc2c1COC2=O>>COc1cc(CCN2CCN(CCc3ccc4c(c3C)COC4=O)CC2)ccc1C#N -US08008491B2,1,CCc1ccc(B(O)O)cc1.O=Cc1c(Cl)[nH]c2ccccc12>>CCc1ccc(-n2c(Cl)c(C=O)c3ccccc32)cc1 -US07902237B2,7,CCNc1ccc(C#N)cc1[N+](=O)[O-]>>CCNc1ccc(C#N)cc1N -US04746657,1,C1CNC1.CN1CC(CCCl)Cc2nc(Cl)ccc2C1=O>>CN1CC(CCN2CCC2)Cc2nc(Cl)ccc2C1=O -US20070208015A1,2,C1COCCN1.Cc1csc(C(=O)O)c1Cl>>Cc1csc(C(=O)N2CCOCC2)c1Cl -US06638929B2,7,N#Cc1cnc2c(sc3c([N+](=O)[O-])cccc32)c1Nc1cccc(Br)c1>>N#Cc1cnc2c(sc3c(N)cccc32)c1Nc1cccc(Br)c1 -US20090004185A1,3,CN(C)c1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccc(I)cc2n1.O=Cc1ccc(B(O)O)cc1>>CN(C)c1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccc(-c3ccc(C=O)cc3)cc2n1 -US20150133443A1,3,C1COCCN1.C=O.COc1cccc2c(=O)[nH]c3scnc3c12>>COc1cccc2c(=O)[nH]c3sc(CN4CCOCC4)nc3c12 -US06413974B1,1,CN.Clc1nc(Cl)c2ncn(C3CCCC3)c2n1>>CNc1nc(Cl)nc2c1ncn2C1CCCC1 -US20110183955A1,2,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1C(=O)O.N[C@@H]1CCCc2ccccc21>>CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21 -US20050009054A1,2,CC(C)(C)OC(=O)NCCC(=O)O.CNc1ccc(C(=O)OC)cc1N>>CNc1ccc(C(=O)OC)cc1NC(=O)CCNC(=O)OC(C)(C)C -US06150385,1,CC(C)(C)OC(=O)N1CCNCC1.Nc1nnc(Br)s1>>CC(C)(C)OC(=O)N1CCN(c2nnc(N)s2)CC1 -US08273745B2,1,CC(=O)Nc1c(N)cccc1OCc1ccccc1.CCOC(=O)CBr>>CCOC(=O)CNc1cccc(OCc2ccccc2)c1NC(C)=O -US05180731,2,CC(c1ccc(-c2ccccc2)c(F)c1)c1csc(N)n1.CCOC(=O)Cl>>CCOC(=O)Nc1nc(C(C)c2ccc(-c3ccccc3)c(F)c2)cs1 -US05739374,7,CC1(C)CCC(C)(C)c2cc(OCc3ccc(C#N)cc3)ccc21>>CC1(C)CCC(C)(C)c2cc(OCc3ccc(CN)cc3)ccc21 -US20110039824A1,3,C=O.CNC.Fc1ccc2cc[nH]c2c1>>CN(C)Cc1c[nH]c2cc(F)ccc12 -US20050080108A1,2,CCOC(=O)c1c(Cl)c2cc(N)ccc2n1C.O=C(O)c1ccccc1-c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1c(Cl)c2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2n1C -US20130072520A2,1,NC(=O)c1c(F)ccc(O)c1F.OCc1cc2cc(C(F)(F)F)ccc2s1>>NC(=O)c1c(F)ccc(OCc2cc3cc(C(F)(F)F)ccc3s2)c1F -US04609398,1,CO.Nc1nc(Cl)nc(Cl)n1>>COc1nc(N)nc(Cl)n1 -US20090018134A1,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)cc3)CCC2)nc(Cl)n1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)cc3)CCC2)nc(-c2ccc(N)cc2)n1 -US08916557B2,1,Clc1ncnc(Cl)n1.Nc1cccc(CS(=O)(=O)c2ccccc2)c1>>O=S(=O)(Cc1cccc(Nc2ncnc(Cl)n2)c1)c1ccccc1 -US20130045986A1,3,CC(C)OC(=O)N1CCC(c2nc3cc(B4OC(C)(C)C(C)(C)O4)ccc3o2)CC1.NC(=O)c1ccc(Br)c(Cl)c1>>CC(C)OC(=O)N1CCC(c2nc3cc(-c4ccc(C(N)=O)cc4Cl)ccc3o2)CC1 -US20010031765A1,2,NCc1ccccc1F.O=C(O)c1ccc2cnccc2n1>>O=C(NCc1ccccc1F)c1ccc2cnccc2n1 -US20070293530A1,2,CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O.NN>>CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NN -US20080227781A1,2,CCCC(N)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1.O=C(O)C(O)c1cc(F)cc(F)c1>>CCCC(NC(=O)C(O)c1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1 -US03962223,8,C=C(CC)C(O)C(=O)OCC>>C=C(CC)C(=O)C(=O)OCC -US04298749,1,COC(=O)Cl.COC(=O)c1c(Oc2cccc(C)c2C)n[nH]c1C>>COC(=O)c1c(Oc2cccc(C)c2C)nn(C(=O)OC)c1C -US07186734B2,3,CCCCn1cc(C(OC)OC)nc1-c1ccccc1.CN(C)C=O>>CCCCn1c(-c2ccccc2)nc(C(OC)OC)c1C=O -US20090320718A1,9,BrC(Br)(Br)Br.OCCCCCCCCCCCSCCC(F)(F)F>>FC(F)(F)CCSCCCCCCCCCCCBr -US20140213554A1,2,Cc1cc(C(=O)O)[nH]n1.Nc1cnc2[nH]c(I)cc2c1>>Cc1cc(C(=O)Nc2cnc3[nH]c(I)cc3c2)[nH]n1 -US20110160207A1,2,COC(=O)c1ccc(C)c(N)c1.O=C(O)c1ccc(Br)s1>>COC(=O)c1ccc(C)c(NC(=O)c2ccc(Br)s2)c1 -US20100256356A1,6,COc1ccc(Cn2nc(N3CCN(C)CC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>CN1CCN(c2n[nH]c3nccc(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)c23)CC1 -US20140336377A1,1,CC(N)=O.COC(=O)c1cc(C)nc(Cl)c1>>COC(=O)c1cc(C)nc(NC(C)=O)c1 -US20100197678A1,1,C1CCNC1.C=CCn1cc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)c2ccc(Br)cc21>>C=CCn1cc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)c2ccc(N3CCCC3)cc21 -US20090247559A1,9,O=C(Cl)c1ccc([N+](=O)[O-])cc1Cl>>O=Cc1ccc([N+](=O)[O-])cc1Cl -US04898863,2,CNC(=O)CCc1cn(Cc2ccc(C(=O)O)cc2OC)c2cc(C(=O)NCC3CCCC3)ccc12.Cc1ccccc1S(N)(=O)=O>>CNC(=O)CCc1cn(Cc2ccc(C(=O)NS(=O)(=O)c3ccccc3C)cc2OC)c2cc(C(=O)NCC3CCCC3)ccc12 -US20090192136A1,2,Fc1ccc(N2CCNCC2)c(Cl)c1.O=C(Cl)c1cc([N+](=O)[O-])ccc1N1CCOCC1>>O=C(c1cc([N+](=O)[O-])ccc1N1CCOCC1)N1CCN(c2ccc(F)cc2Cl)CC1 -US05660829,7,CC(C)(C)OC(=O)C(C[C@H](NC(=O)Cc1ccccc1)C(=O)OC(C)(C)C)[N+](=O)[O-]>>CC(C)(C)OC(=O)C(N)C[C@H](NC(=O)Cc1ccccc1)C(=O)OC(C)(C)C -US20150057263A1,6,COc1cc2nc(Cl)nc(SC3CCN(C(=O)OC(C)(C)C)CC3)c2cc1OC>>COc1cc2nc(Cl)nc(SC3CCNCC3)c2cc1OC -US20140187529A1,3,Cc1c(C(=O)Nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c(=O)n(-c2ccccc2)n1C.Nc1ncc(Br)nc1Br>>Cc1c(C(=O)Nc2ccc(-c3nc(Br)cnc3N)cc2)c(=O)n(-c2ccccc2)n1C -US20060229336A1,2,CC(C)(C)C(=O)Cl.Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2cccc(F)c2)CCN(C(=O)C2(N)CCCC2)CC1>>Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2cccc(F)c2)CCN(C(=O)C2(NC(=O)C(C)(C)C)CCCC2)CC1 -US06028096,3,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1I.O=C(Cl)C1CC1>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1C(=O)C1CC1 -US20140296261A1,3,CC1(C)OB(c2ccccc2N)OC1(C)C.Clc1ncnc2c1ncn2C1CCCCO1>>Nc1ccccc1-c1ncnc2c1ncn2C1CCCCO1 -US20120220585A1,3,CCCC[Sn](CCCC)(CCCC)c1cccc(C)n1.C[C@@H](c1cc2cccc(Cl)c2nc1Cl)N1C(=O)c2ccccc2C1=O>>Cc1cccc(-c2nc3c(Cl)cccc3cc2[C@H](C)N2C(=O)c3ccccc3C2=O)n1 -US20120065196A1,1,CCC=O.O=C(NCCNC(=O)C1CCCNC1)c1cn(-c2ccccc2)nc1C(F)(F)F>>CCCN1CCCC(C(=O)NCCNC(=O)c2cn(-c3ccccc3)nc2C(F)(F)F)C1 -US20100234351A1,1,CC(C)(C)NC(=O)c1cccc(Oc2ccc(Nc3ncnc4c3C=C(C=O)CCN4)cc2Cl)c1.CNCCS(C)(=O)=O>>CN(CCS(C)(=O)=O)CC1=Cc2c(ncnc2Nc2ccc(Oc3cccc(C(=O)NC(C)(C)C)c3)c(Cl)c2)NCC1 -US20050234029A1,6,CC(=O)Nc1ccc(-c2cc(-c3c(-c4cccc(C)n4)nc4ccccn34)ccn2)cc1>>Cc1cccc(-c2nc3ccccn3c2-c2ccnc(-c3ccc(N)cc3)c2)n1 -US20090069326A1,6,CC(C)[Si](O[C@@H]1CC[C@@H](N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(C(=O)N5CCC(C(F)(F)F)CC5)cc4)cc3Cl)C2=O)CC1)(C(C)C)C(C)C>>O=C(c1ccc(-c2cc(Cl)c(C[C@@H]3CCN([C@@H]4CC[C@@H](O)CC4)C3=O)c(Cl)c2)cc1)N1CCC(C(F)(F)F)CC1 -US20060264494A1,2,CN[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1.COCC(=O)O>>COCC(=O)N(C)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1 -US08273754B2,6,CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2ccccc2)c2ccccc2C1>>NC1CCN(S(=O)(=O)c2ccccc2)c2ccccc2C1 -US08178577B2,2,Nc1ccc(Cl)cc1N.O=C(O)CCCCCNC(=O)C=C1c2ccccc2-c2ccccc21>>Nc1cc(Cl)ccc1NC(=O)CCCCCNC(=O)C=C1c2ccccc2-c2ccccc21 -US20070254913A1,1,C1COCCN1.CCc1nn(C(C)C)c2nc(-c3ccn(-c4ncc(Br)cn4)n3)ccc12>>CCc1nn(C(C)C)c2nc(-c3ccn(-c4ncc(N5CCOCC5)cn4)n3)ccc12 -US07459469B2,3,Brc1cnc2occc2c1.C=CCC(C)N(C)C(=O)OC(C)(C)C>>CC(C/C=C/c1cnc2occc2c1)N(C)C(=O)OC(C)(C)C -US06051581,2,CCOC(=O)CC1(O)CN2CCC1C2.NN>>NNC(=O)CC1(O)CN2CCC1C2 -US20150152108A1,1,COc1cc(Cl)nc2c1NC[C@H](CCO)N2>>COc1cc(Cl)nc2c1N1CC[C@@H](C1)N2 -US20110118283A1,6,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cn3)[C@H]2c2cccc(Cl)c2F)cc1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cn1 -US20100137290A1,1,COc1ccc(CCl)c(OC)c1.O=C1COc2ccc(Br)nc2N1>>COc1ccc(CN2C(=O)COc3ccc(Br)nc32)c(OC)c1 -US20120015972A1,6,CCOC(=O)c1ccn2ccc(C#N)c2c1>>N#Cc1ccn2ccc(C(=O)O)cc12 -US08481568B2,2,CN.O=C(O)CNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>CNC(=O)CNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O -US04035376,9,CC(C(=O)Cl)c1ccc(C(=O)c2cccs2)cc1.N>>CC(C(N)=O)c1ccc(C(=O)c2cccs2)cc1 -US07968570B2,1,C1COCCN1.Cc1cc(C=O)cc2c1C(=O)N(Cc1ccc(OC(F)(F)F)cc1)C2>>Cc1cc(CN2CCOCC2)cc2c1C(=O)N(Cc1ccc(OC(F)(F)F)cc1)C2 -US04670593,2,CC(C)N.CCOC(=O)C(F)Br>>CC(C)NC(=O)C(F)Br -US05326905,2,COC(=O)[C@@H](N)Cc1ccccc1.O=C(Cl)CCc1ccc(CCl)cc1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccc(CCl)cc1 -US20150051402A1,2,CCN.CCOC(=O)c1sc(C)nc1C>>CCNC(=O)c1sc(C)nc1C -US20140113922A1,1,CC(C)(C)OC(=O)NCCc1ccc(Oc2ccc(F)cc2)cc1.CI>>CN(CCc1ccc(Oc2ccc(F)cc2)cc1)C(=O)OC(C)(C)C -US05569659,9,CCOC(=O)N1CCC(O)(c2ccccc2OC(C)C)CC1>>CCOC(=O)N1CCC(c2ccccc2OC(C)C)CC1 -US20130291227A1,2,CCN(C(=O)CNC)c1cn(-c2cccnc2)nc1Cl.CS(=O)(=O)Cl>>CCN(C(=O)CN(C)S(C)(=O)=O)c1cn(-c2cccnc2)nc1Cl -US20110201628A1,1,C[C@H](N)c1ncc(F)cn1.Cc1ccc(S(=O)(=O)n2ccc3c(Nc4cn(C)cn4)nc(Cl)nc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4cn(C)cn4)nc(N[C@@H](C)c4ncc(F)cn4)nc32)cc1 -US20050148624A1,3,COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc2c(c1)OCO2.OB(O)c1ccccc1>>COC(=O)c1c(-c2ccccc2)c2cc(-c3ccccc3)ccc2c(=O)n1Cc1ccc2c(c1)OCO2 -US20120302566A1,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)cccc43)ccc21.Cn1ccnc1I>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5nccn5C)cccc43)ccc21 -US20110053925A1,1,CC(C)(C)OC(=O)N1CCNCC1.COC(=O)/C=C/c1ccc(C=O)cc1>>COC(=O)/C=C/c1ccc(CN2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20060189625A1,1,CS(=O)(=O)OCCCC1CCCC1.Fc1cc(N2CCNCC2)ccc1OCc1ccccc1>>Fc1cc(N2CCN(CCCC3CCCC3)CC2)ccc1OCc1ccccc1 -US20140058098A1,7,COCc1nc(-c2cn3c(n2)-c2ccc(C4=CCN(C(=O)OC(C)(C)C)CC4)cc2OCC3)n(C(C)C)n1>>COCc1nc(-c2cn3c(n2)-c2ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc2OCC3)n(C(C)C)n1 -US05877174,6,CCOC(=O)CC(c1cccnc1)N1CCN(CCCOc2ccc(C#N)cc2)C(=O)C1=O>>N#Cc1ccc(OCCCN2CCN(C(CC(=O)O)c3cccnc3)C(=O)C2=O)cc1 -US08389720B2,2,Cn1c(=O)c(CNCC(c2ccccc2)C2CCN(C(=O)OC(C)(C)C)CC2)cc2ccccc21.O=C(O)C1CCCCC1>>Cn1c(=O)c(CN(CC(c2ccccc2)C2CCN(C(=O)OC(C)(C)C)CC2)C(=O)C2CCCCC2)cc2ccccc21 -US06509361B1,9,COC(=O)c1cnn(-c2ccc(F)cc2)c1-c1ccncc1.N>>NC(=O)c1cnn(-c2ccc(F)cc2)c1-c1ccncc1 -US08765940B2,1,Cc1c(-c2cccc(F)c2)nc2ncccc2c1Cl.c1nc2c(cc1N1CCOCC1)NCC21CCOCC1>>Cc1c(-c2cccc(F)c2)nc2ncccc2c1N1CC2(CCOCC2)c2ncc(N3CCOCC3)cc21 -US20080275054A1,1,C1COCCN1.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1ncnc2c1cnn2-c1ccc(Br)cc1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1ncnc2c1cnn2-c1ccc(N2CCOCC2)cc1 -US08378118B2,7,COc1ccc(OC)c2c1CCC2=O>>COc1ccc(OC)c2c1CCC2 -US20080312226A1,2,N#Cc1ccc(N=C=O)cc1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>N#Cc1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)cc1 -US20060160832A1,7,CCOC(=O)c1cc2c(Oc3ccc([N+](=O)[O-])cc3)ncnc2[nH]1>>CCOC(=O)c1cc2c(Oc3ccc(N)cc3)ncnc2[nH]1 -US20090325936A1,2,CC12CCC(C1)C(C)(C)C2N.O=C(O)c1nc(CN2CCOCC2)c2ccccn12>>CC12CCC(C1)C(C)(C)C2NC(=O)c1nc(CN2CCOCC2)c2ccccn12 -US08188301B2,1,C=O.OC1(c2ccc(F)c(F)c2)CCNC1>>CN1CCC(O)(c2ccc(F)c(F)c2)C1 -US08518972B2,1,COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CBr)cc3)cccc2C1=O.c1nc[nH]n1>>COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(Cn4cncn4)cc3)cccc2C1=O -US05089485,9,CCCCCCCCCCCCC(Cl)c1coc([Si](C)(C)C)c1.[N-]=[N+]=[N-]>>CCCCCCCCCCCCC(N=[N+]=[N-])c1coc([Si](C)(C)C)c1 -US20110294850A1,2,O=C=Nc1cccc(Oc2ccccc2)c1.Oc1ccc2c(c1)CCN2Cc1ccccc1>>O=C(Nc1cccc(Oc2ccccc2)c1)Oc1ccc2c(c1)CCN2Cc1ccccc1 -US20040018941A1,9,Cc1cc2c(N)c(F)cc(Cl)c2o1.S=C(Cl)Cl>>Cc1cc2c(N=C=S)c(F)cc(Cl)c2o1 -US20150057247A1,1,CCOC(=O)c1cc([Si](C)(C)C)n[nH]1.O=C(CBr)c1cccnc1>>CCOC(=O)c1cc([Si](C)(C)C)nn1CC(=O)c1cccnc1 -US20040249151A1,1,CNCC1CCN(C(=O)OC(C)(C)C)CC1.Clc1ccc(Cl)nn1>>CN(CC1CCN(C(=O)OC(C)(C)C)CC1)c1ccc(Cl)nn1 -US07504401B2,6,O=C(Nc1cc(Br)cc(-c2nc3ccccc3o2)c1)OCc1ccccc1>>Nc1cc(Br)cc(-c2nc3ccccc3o2)c1 -US20070254881A1,4,COC(=O)C(=O)CC(=O)c1cnn(C)c1.NNc1ccc(Cl)nn1>>COC(=O)c1cc(-c2cnn(C)c2)n(-c2ccc(Cl)nn2)n1 -US20100190766A1,6,COC(=O)c1ccc(C#CC#CC#CC2CC2)cc1>>O=C(O)c1ccc(C#CC#CC#CC2CC2)cc1 -US08846709B2,7,COc1cc2c(NCC3CCOCC3)c([N+](=O)[O-])cnc2cc1-c1c(C)noc1C>>COc1cc2c(NCC3CCOCC3)c(N)cnc2cc1-c1c(C)noc1C -US20090156572A1,2,CC(=O)O.CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1>>CC(=O)N1CC[C@@H](N(C)C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](c2ccc(Cl)c(Cl)c2)C1 -USRE029358,1,N=C(N)NN.O=C(C=Cc1ccc2ccccc2c1)C=Cc1ccc2ccccc2c1>>N=C(N)NN=C(C=Cc1ccc2ccccc2c1)C=Cc1ccc2ccccc2c1 -US20130112961A1,4,O=C(NNC(=O)c1ccc(I)cc1)c1ccccc1>>Ic1ccc(-c2nnc(-c3ccccc3)o2)cc1 -US20100267712A1,1,CCBr.O=C1c2cc(O)ccc2CN1c1ccc2sccc2c1>>CCOc1ccc2c(c1)C(=O)N(c1ccc3sccc3c1)C2 -US20150218124A1,6,COc1cc(C#N)c(Cc2cc(C)cc(C)c2)c(C#N)c1O>>Cc1cc(C)cc(Cc2c(C#N)cc(O)c(O)c2C#N)c1 -US04039589,7,C#CC(O)(c1ccccc1)c1cc(C)ccc1C>>CCC(O)(c1ccccc1)c1cc(C)ccc1C -US08637501B2,1,Cn1c2c(c3ccc(Br)cc31)CN(C(=O)OC(C)(C)C)CCC2.O=c1cc(OCc2ccc(Cl)cc2)cc[nH]1>>Cn1c2c(c3ccc(-n4ccc(OCc5ccc(Cl)cc5)cc4=O)cc31)CN(C(=O)OC(C)(C)C)CCC2 -US20100298347A1,7,O=C(c1cc(Br)cs1)C(F)F>>OC(c1cc(Br)cs1)C(F)F -US06841556B2,7,COc1ccc(-c2[nH]nc(C)c2[N+](=O)[O-])cc1OC>>COc1ccc(-c2[nH]nc(C)c2N)cc1OC -US20100145057A1,2,C1CCNC1.CC(=NO)C(=O)O>>CC(=NO)C(=O)N1CCCC1 -US04372953,2,CN=C=S.Cn1nnnc1SCCCN>>CNC(=S)NCCCSc1nnnn1C -US05424320,9,ClC(Cl)(Cl)Cl.O=c1cc(-c2ccsc2)c2ccc(CO)cc2o1>>O=c1cc(-c2ccsc2)c2ccc(CCl)cc2o1 -US20070208033A1,2,CC(C)(C)OC(=O)NCc1ccc(C(=O)O)cc1.CCCN(CCC)Cc1ccc(N)cc1>>CCCN(CCC)Cc1ccc(NC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)cc1 -US05093364,5,Nc1cc(F)ccc1C(=O)O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)c1ccc(F)cc1NC(=O)C(F)(F)F -US07345067B2,1,CCOC(=O)COc1c(C)cc(NCc2oc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C.CI>>CCOC(=O)COc1c(C)cc(N(C)Cc2oc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C -US05166170,1,NCC(=O)c1ccccc1.NNc1ccc(Cl)cc1>>NCC(=NNc1ccc(Cl)cc1)c1ccccc1 -US20110112134A1,6,CC(C)(C)OC(=O)Cn1c(CCCO[Si](C)(C)C(C)(C)C)cc2ncccc21>>CC(C)(C)OC(=O)Cn1c(CCCO)cc2ncccc21 -US08895050B2,2,COC(=O)[C@H](N)CC(C)C.COc1cc(C(=O)O)cc(OC)n1>>COC(=O)[C@@H](CC(C)C)NC(=O)c1cc(OC)nc(OC)c1 -US08053447B2,2,CCOC(=O)c1ccc(OC2CCC(N)CC2)cc1.O=C(Cl)C1CC1>>CCOC(=O)c1ccc(OC2CCC(NC(=O)C3CC3)CC2)cc1 -US20020169184A1,2,NCCCCO.O=C(O)c1ccc2c(c1)OCO2>>O=C(NCCCCO)c1ccc2c(c1)OCO2 -US20120040981A1,1,Brc1ccccc1.C1CC2(CCN1)OCCO2>>c1ccc(N2CCC3(CC2)OCCO3)cc1 -US08815869B2,2,CCO.O=C(O)C(c1ccccc1)c1ccccc1>>CCOC(=O)C(c1ccccc1)c1ccccc1 -US06251911B1,1,Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12.O=Cc1ccoc1>>Clc1cccc(Nc2ncnc3[nH]nc(N=Cc4ccoc4)c23)c1 -US20090093633A1,1,CCc1nnn([C@@H]2C=C[C@H](n3cnc4c(Cl)nc(Cl)nc43)C2)n1.NCC(c1ccccc1)c1ccccc1>>CCc1nnn([C@@H]2C=C[C@H](n3cnc4c(NCC(c5ccccc5)c5ccccc5)nc(Cl)nc43)C2)n1 -US04927926,1,CC1(CNC(=O)C(F)(F)F)CNC1.O=C(O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O>>CC1(CNC(=O)C(F)(F)F)CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)C1 -US20100210642A1,3,C#Cc1cnn2c(C(F)(F)F)cc(-c3cccc(C(F)(F)F)c3)nc12.NS(=O)(=O)c1ccc(Br)cc1>>NS(=O)(=O)c1ccc(C#Cc2cnn3c(C(F)(F)F)cc(-c4cccc(C(F)(F)F)c4)nc23)cc1 -US20130190290A1,2,COc1cc(C(=O)O)cc(S(F)(F)(F)(F)F)c1.Cc1ccc(N)cc1-n1ccn2nc(-c3cccnc3)cc12>>COc1cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)cc(S(F)(F)(F)(F)F)c1 -US05208250,3,O=C1CNC(=S)N1.O=Cc1ccc(O)c(Br)c1>>O=C1NC(=S)NC1=Cc1ccc(O)c(Br)c1 -US20120322788A1,1,CS(=O)(=O)OCCOc1cccc(C=O)c1.Cc1nc(C(=O)N2CCOC3(CCNCC3)C2)cs1>>Cc1nc(C(=O)N2CCOC3(CCN(CCOc4cccc(C=O)c4)CC3)C2)cs1 -US20110275797A1,3,COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(Br)ccc1OC(C)=O.OB(O)c1ccco1>>COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(-c2ccco2)ccc1OC(C)=O -US20100173898A1,2,CC1=NN(c2ccc(C(=O)O)cc2)C(=O)C1.Cc1cc(N2CCC(CN3CCCC3C)C2)ccc1N>>CC1=NN(c2ccc(C(=O)Nc3ccc(N4CCC(CN5CCCC5C)C4)cc3C)cc2)C(=O)C1 -US08263606B2,2,CN1C(=O)C2(COc3cc4c(cc32)OCCO4)c2c(C(=O)O)cccc21.NC1CCCCC1>>CN1C(=O)C2(COc3cc4c(cc32)OCCO4)c2c(C(=O)NC3CCCCC3)cccc21 -US20130040930A1,2,CCOC(=O)c1ccc(N2CCCS2(=O)=O)nc1.Cc1cnc(N2CCNCC2)c(C2CC2)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCS4(=O)=O)nc3)CC2)c(C2CC2)c1 -US20090018124A1,4,Nc1ccc(C(F)(F)F)cc1N.O=C(O)c1ccc(-c2ncccc2Cl)cc1>>FC(F)(F)c1ccc2nc(-c3ccc(-c4ncccc4Cl)cc3)[nH]c2c1 -US06235731B1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.Clc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC(=Cc2ccccc2Cl)CC1 -US20130237535A1,2,COc1cc(S(=O)(=O)Cl)ccc1Br.O=C1COC2(CCNCC2)CN1C1CC1>>COc1cc(S(=O)(=O)N2CCC3(CC2)CN(C2CC2)C(=O)CO3)ccc1Br -US20110129443A1,2,COc1ccc(C(C)=O)c(N)c1Cl.O=C(O)c1nc(C(F)(F)F)cs1>>COc1ccc(C(C)=O)c(NC(=O)c2nc(C(F)(F)F)cs2)c1Cl -US20150018363A1,1,COC(=O)c1cc[nH]c(=O)c1.Cc1c(C2CC2)nc2ccc(I)cn12>>COC(=O)c1ccn(-c2ccc3nc(C4CC4)c(C)n3c2)c(=O)c1 -US09108947B2,2,Cc1c([C@@H](O)CN2CCCC2CN)ccc2c1COC2=O.O=S(=O)(Cl)c1ccc(-n2cnnn2)cc1>>Cc1c([C@@H](O)CN2CCCC2CNS(=O)(=O)c2ccc(-n3cnnn3)cc2)ccc2c1COC2=O -US20110257151A1,3,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(Br)c1)N2.O=C(O)c1ccc(B(O)O)cc1>>CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(-c3ccc(C(=O)O)cc3)c1)N2 -US04223033,7,O=C(O)c1cccc(Sc2ccccc2)n1>>OCc1cccc(Sc2ccccc2)n1 -US07572808B2,3,CC1(C)OB(c2ccncc2)OC1(C)C.Cc1nc(C(F)(F)F)ccc1Cn1nc2c(Br)c(Cl)ccn2c1=O>>Cc1nc(C(F)(F)F)ccc1Cn1nc2c(-c3ccncc3)c(Cl)ccn2c1=O -US20090192167A1,2,Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1N.O=C(Cl)c1cccc(NC(=O)c2ccccc2)c1>>Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(NC(=O)c2ccccc2)c1 -US06525072B1,3,Nc1ccc2c(c1)CCC2=O.O=C1Cc2ccccc2N1>>Nc1ccc2c(c1)CCC2=C1C(=O)Nc2ccccc21 -US08648200B2,6,COC(=O)c1ccc(C(F)F)cc1>>O=C(O)c1ccc(C(F)F)cc1 -US20090124602A1,9,O=C(c1cn(Cc2ccccc2)cn1)c1cccnc1F.[NH4+]>>Nc1ncccc1C(=O)c1cn(Cc2ccccc2)cn1 -US20040058903A1,7,O=[N+]([O-])c1ccc(NCCc2ccccn2)nc1>>Nc1ccc(NCCc2ccccn2)nc1 -US05693636,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1cccc([N+](=O)[O-])c1>>CC(C)(C)OC(=O)NCc1cccc([N+](=O)[O-])c1 -US06833372B2,2,COc1nc(NCCCN2CCOCC2)nc(OC)c1N.Cc1cc2c(c(C)c1Cc1ccc(C(=O)O)o1)C(C)(C)CCO2>>COc1nc(NCCCN2CCOCC2)nc(OC)c1NC(=O)c1ccc(Cc2c(C)cc3c(c2C)C(C)(C)CCO3)o1 -US20150119411A1,6,COC(=O)c1ccc(Cn2c(=O)c3ccccc3n(Cc3ccc(C)cc3)c2=O)cc1>>Cc1ccc(Cn2c(=O)n(Cc3ccc(C(=O)O)cc3)c(=O)c3ccccc32)cc1 -US04634770,6,CC(=O)NC(C)CNS(=O)(=O)c1cccc2cnccc12>>CC(N)CNS(=O)(=O)c1cccc2cnccc12 -US07709496B2,3,COC(=O)CP(=O)(OCC(F)(F)F)OCC(F)(F)F.O=Cc1cc(Cl)cc(Br)c1O>>COC(=O)/C=C/c1cc(Cl)cc(Br)c1O -US05506256,2,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(O)COc1ccc(F)cc1.NCc1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(O)COc1ccc(F)cc1 -US20060205774A1,2,C1=C(c2ccc(OCc3ccccc3)cc2)CCNC1.O=C(O)C1CCOCC1>>O=C(C1CCOCC1)N1CC=C(c2ccc(OCc3ccccc3)cc2)CC1 -US07244747B2,1,O=C1Cc2ccccc2N1CO.c1ccc2[nH]cnc2c1>>O=C1Cc2ccccc2N1Cn1cnc2ccccc21 -US05258380,1,BrCCBr.CCn1nn[nH]c1=O>>CCn1nnn(CCBr)c1=O -US20100298377A1,7,C[Si](C)(C)CCOCn1cc2ccc([N+](=O)[O-])cc2n1>>C[Si](C)(C)CCOCn1cc2ccc(N)cc2n1 -US06013658,6,CN(C(=O)OC(C)(C)C)[C@H](Cc1ccccc1)c1nnc(C(N)=O)o1>>CN[C@H](Cc1ccccc1)c1nnc(C(N)=O)o1 -US20090247567A1,2,CN(C(=O)c1cc2c(s1)-c1cc(C(=O)O)ccc1OC2)c1ccc(F)cc1F.CNC>>CN(C)C(=O)c1ccc2c(c1)-c1sc(C(=O)N(C)c3ccc(F)cc3F)cc1CO2 -US06090969,7,COP(=O)(OC)[C@H](O)C=C(C)C>>COP(=O)(OC)[C@H](O)CC(C)C -US20060235062A1,7,COC(=O)C(Cc1cc(OC)cc(OC)c1)c1ccc(Oc2ccc(C=C3SC(=O)NC3=O)cc2)cc1>>COC(=O)C(Cc1cc(OC)cc(OC)c1)c1ccc(Oc2ccc(CC3SC(=O)NC3=O)cc2)cc1 -US09102607B2,2,CCOC(=O)Cl.O=C(O)c1ccccc1O>>CCOC(=O)Oc1ccccc1C(=O)O -US20070123504A1,2,COCCCNc1ccc(N)cn1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>COCCCNc1ccc(NC(=O)c2nc(-c3ccccc3)oc2C(F)(F)F)cn1 -US20070123515A1,1,CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1.Cc1ccc(B(O)O)cc1>>Cc1ccc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(OC4CCN(C(C)C)CC4)ccc32)cc1 -US08357707B2,7,O=C[C@@]12CCCN1[C@@H](C(Cl)(Cl)Cl)OC2=O>>O=C1O[C@H](C(Cl)(Cl)Cl)N2CCC[C@@]12CO -US20100204196A1,7,CCCN1CCC=C(c2ccc(OC)c([N+](=O)[O-])c2)C1>>CCCN1CCC=C(c2ccc(OC)c(N)c2)C1 -US07709471B2,1,CCN1CCC(NC(=O)c2cc(F)c(N)cc2F)CC1.CN1C(=O)C2(CC2)CN(C2CCCC2)c2nc(Cl)ncc21>>CCN1CCC(NC(=O)c2cc(F)c(Nc3ncc4c(n3)N(C3CCCC3)CC3(CC3)C(=O)N4C)cc2F)CC1 -US20060172999A1,1,C=CC1CCOC(O)C1c1ccc(F)c(Br)c1.C[C@@H](O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C=C[C@@H]1CCO[C@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]1c1ccc(F)c(Br)c1 -US20120232056A1,6,COC(=O)c1ccc2nc(-c3ccc(C(N)=O)cc3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc(C(N)=O)cc1 -US20040209931A1,1,BrCc1ccccc1.O[C@H]1CCC[C@@H](O)C1>>O[C@H]1CCC[C@@H](OCc2ccccc2)C1 -US04282230,1,OC(Cn1ccnc1)c1ccc(Cl)cc1Cl.Oc1cc(CBr)c2ccccc2n1>>Oc1cc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c2ccccc2n1 -US08273767B2,1,O=c1cccn[nH]1.OCCc1ccc2cc(Br)ccc2c1>>O=c1cccnn1-c1ccc2cc(CCO)ccc2c1 -US20120101134A1,1,CCOC(=O)CBr.CCc1c(O)cccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1>>CCOC(=O)COc1cccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c1CC -US06936602B1,6,COC(=O)C1=Cc2cc(-c3ccc(OCCOC(C)C)cc3)ccc2N(S(C)(=O)=O)CC1>>CC(C)OCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3S(C)(=O)=O)cc1 -US20090069340A1,1,Clc1ccccc1N1CCNCC1.Cn1c(CBr)c(Cl)c(=O)n1C1CCCCC1>>Cn1c(CN2CCN(c3ccccc3Cl)CC2)c(Cl)c(=O)n1C1CCCCC1 -US20030078249A1,2,COc1cc(CC(=O)O)ccc1NC(=O)Nc1ccccc1Br.C[C@H](N)COc1ccc(C(=O)OCc2ccccc2)cc1>>COc1cc(CC(=O)N[C@@H](C)COc2ccc(C(=O)OCc3ccccc3)cc2)ccc1NC(=O)Nc1ccccc1Br -US07674789B2,2,Cc1c(F)cc(C(=O)O)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F.Nc1ccc(F)cc1>>Cc1c(F)cc(C(=O)Nc2ccc(F)cc2)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F -US09102591B2,2,Cc1ncc(C(CN)CC2(C(F)(F)F)CC2)cn1.O=C(O)c1ccccc1Cl>>Cc1ncc(C(CNC(=O)c2ccccc2Cl)CC2(C(F)(F)F)CC2)cn1 -US04259336,2,COC(=O)C1=C(O)c2sc3ccccc3c2S(=O)(=O)N1C.Nc1ccc(Cl)cn1>>CN1C(C(=O)Nc2ccc(Cl)cn2)=C(O)c2sc3ccccc3c2S1(=O)=O -US20140107109A1,1,CC1(C)C(N)=N[C@](C)(c2cc(Br)ccc2F)CS1(=O)=O.Sc1cccc2ccccc12>>CC1(C)C(N)=N[C@](C)(c2cc(Sc3cccc4ccccc34)ccc2F)CS1(=O)=O -US20030162795A1,3,Cc1cc2cc(Nc3ccnc4cc(Br)sc34)ccc2[nH]1.OB(O)c1ccccc1>>Cc1cc2cc(Nc3ccnc4cc(-c5ccccc5)sc34)ccc2[nH]1 -US06107251,8,O=C(NC1CCCCC1O)c1ncccc1OCc1ccccc1>>O=C(NC1CCCCC1=O)c1ncccc1OCc1ccccc1 -US20130203995A1,3,CCOC(=O)c1ccoc1.CN(C)C=O>>CCOC(=O)c1coc(C=O)c1 -US06326503B1,1,CC[Si](CC)(CC)OC(C)(C)/C=C/CBr.C[C@H](O)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CC[Si](CC)(CC)OC(C)(C)/C=C/CO[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C -US20150011779A1,6,CCOC(=O)c1c(C(F)F)nn(C(C)(C)C)c1C(F)F>>CC(C)(C)n1nc(C(F)F)c(C(=O)O)c1C(F)F -US20110130453A1,2,CCNCc1cc([N+](=O)[O-])ccc1Oc1cc(CC(=O)OCC)ccc1OC.O=C(Cl)OCc1ccccc1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc([N+](=O)[O-])cc2CN(CC)C(=O)OCc2ccccc2)c1 -US08008505B2,6,CCOC(=O)C(c1c2ccccc2nn1-c1ccc(Cl)cc1)C1CCCCC1>>O=C(O)C(c1c2ccccc2nn1-c1ccc(Cl)cc1)C1CCCCC1 -US08975254B2,1,Cc1cc(-c2cc[nH]n2)ccc1C#N.O=C1c2ccccc2C(=O)N1CCBr>>Cc1cc(-c2ccn(CCN3C(=O)c4ccccc4C3=O)n2)ccc1C#N -US08034563B1,3,C#Cc1ccc(CO)cc1.NCc1ccc(I)cc1>>NCc1ccc(C#Cc2ccc(CO)cc2)cc1 -US06358985B1,3,COc1cccc(CCBr)c1.O=Cc1ccccc1>>COc1cccc(CCC(O)c2ccccc2)c1 -US20030166936A1,6,CCOC(=O)c1cn(C2CC2)c2c(OC)c(Cl)c(F)cc2c1=O>>COc1c(Cl)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US08283354B2,2,Cc1ccc2c(N3CCC(N)CC3)nc(-c3ccccc3O)nc2c1.O=C(O)[C@H]1CCCO1>>Cc1ccc2c(N3CCC(NC(=O)[C@H]4CCCO4)CC3)nc(-c3ccccc3O)nc2c1 -US05166212,6,CC(C)(C)C(=O)OCOC(=O)[C@@H](Cc1ccccc1)C[C@H](Cc1ccccc1)C(=O)OCc1ccccc1>>CC(C)(C)C(=O)OCOC(=O)[C@@H](Cc1ccccc1)C[C@H](Cc1ccccc1)C(=O)O -US20070112059A1,6,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1C[C@@H](F)C[C@H]1C#N>>N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H]1Cc2ccccc2CN1 -US20130172292A1,3,CC1(C)OB(c2ccc(C(=O)c3nc4ccccc4n3COCC[Si](C)(C)C)cc2)OC1(C)C.CCn1nc(Br)c2ncccc21>>CCn1nc(-c2ccc(C(=O)c3nc4ccccc4n3COCC[Si](C)(C)C)cc2)c2ncccc21 -US07553979B2,6,COc1cc(OC)c2c(c1)OCCCC=CCCCOC2=O>>COc1cc(O)c2c(c1)OCCCC=CCCCOC2=O -US05472983,2,CC(C)(C)C(=O)Cl.Nc1ccccc1>>CC(C)(C)C(=O)Nc1ccccc1 -US06803484B2,7,CC(C#N)c1ccccc1>>CC(CN)c1ccccc1 -US05026740,8,CC(C)(Sc1ccccc1)C(=O)c1ccccc1.OO>>CC(C)(C(=O)c1ccccc1)S(=O)c1ccccc1 -US04420630,2,O=C(Cl)c1ccc(CCBr)cc1.O=S(=O)(Nc1ccccc1)c1ccc(O)cc1>>O=C(Oc1ccc(S(=O)(=O)Nc2ccccc2)cc1)c1ccc(CCBr)cc1 -US04096265,1,CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CNCC1.N#CBr>>CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CN(C#N)CC1 -US05491167,1,CCC(Oc1ccc(C)cc1C)C(=O)O.C[C@H]1C=CC2=C[C@@H](C(C)(C)C)C[C@H](O)[C@@H]2[C@@]1(CC[C@@H]1C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O1)O[SiH](C)C>>CCC(Oc1ccc(C)cc1C)C(=O)O[C@H]1C[C@H](C(C)(C)C)C=C2C=C[C@H](C)[C@](CC[C@@H]3C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O3)(O[SiH](C)C)[C@H]21 -US20090318431A1,7,CN(Cc1ccccc1)c1c(F)cc([N+](=O)[O-])cc1CCO[Si](C)(C)C(C)(C)C>>CN(Cc1ccccc1)c1c(F)cc(N)cc1CCO[Si](C)(C)C(C)(C)C -US04255581,1,CC(C)(C)C(=O)OCOC(=O)c1cccnc1Cl.Cc1c(N)cccc1Cl>>Cc1c(Cl)cccc1Nc1ncccc1C(=O)OCOC(=O)C(C)(C)C -US08921389B2,2,COC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2C)c1O.NCCC(=O)O>>Cn1c(=O)c(-c2ccccc2)cc2c(O)c(C(=O)NCCC(=O)O)ncc21 -US07179823B1,2,CCOC(=O)CCc1cn(Cc2ccc(C(=O)O)cc2)nc1-c1ccccc1.Cc1oc(-c2ccccc2)nc1CN>>CCOC(=O)CCc1cn(Cc2ccc(C(=O)NCc3nc(-c4ccccc4)oc3C)cc2)nc1-c1ccccc1 -US07820660B2,6,CO[C@@H]1C[C@@H](c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)N(C(=O)OCc2ccccc2)C1>>CO[C@H]1CN[C@H](c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)C1 -US20070208004A1,1,Nc1ccccc1.O=CCc1ccccc1>>c1ccc(CCNc2ccccc2)cc1 -US05187006,1,C=CCCl.COC(CN)OC>>C=CCNCC(OC)OC -US20110014140A1,3,CCCCC(CC)COC(=O)CC#N.O=C(c1ccccc1)c1ccccc1>>CCCCC(CC)COC(=O)C(C#N)=C(c1ccccc1)c1ccccc1 -US20130079306A1,2,NCCc1ccc(O)cc1.O=C(O)c1cc(-c2ccc(Cl)cc2Cl)n[nH]1>>O=C(NCCc1ccc(O)cc1)c1cc(-c2ccc(Cl)cc2Cl)n[nH]1 -US20120289474A1,6,CCn1nnc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4F)cc32)n1>>CCn1nnc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4F)cc32)n1 -US08609848B2,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OC.O=C(O)c1ccc2ccccc2n1>>COc1ccc(C2=NN(C3CCN(C(=O)c4ccc5ccccc5n4)CC3)C(=O)C2(C)C)cc1OC -US07767691B2,1,BrCCc1cc2ccccc2[nH]1.N#CC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2>>N#CC(c1ccccc1)(c1ccccc1)C12CC[N+](CCc3cc4ccccc4[nH]3)(CC1)C2 -US06432950B1,1,Clc1nc(Cl)c2c3c(sc2n1)CCCC3.NCc1ccc(Cl)c(Cl)c1>>Clc1nc(NCc2ccc(Cl)c(Cl)c2)c2c3c(sc2n1)CCCC3 -US20120232059A1,2,CN1CCNCC1.O=S(=O)(Cl)c1ccc(Br)cc1>>CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 -US20130102600A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1nc2sc(-c3ccccc3)cc2c(=O)[nH]1>>CC(C)(C)OC(=O)Nc1nc2sc(-c3ccccc3)cc2c(=O)[nH]1 -US07943636B2,3,CCOP(=O)(CC(C)=O)OCC.O=C1CCOCC1>>CC(=O)C=C1CCOCC1 -US20120142668A1,6,CC(C)C[C@@H](/C=C/C(=O)N1CCc2ccccc21)NC(=O)[C@@H]1CCCCN1C(=O)OC(C)(C)C>>CC(C)C[C@@H](/C=C/C(=O)N1CCc2ccccc21)NC(=O)[C@@H]1CCCCN1 -US20090221555A1,1,CC1(C)CCC(=O)Nc2ccc(N)cc21.FC(F)(F)c1c[nH]c(-c2ccccc2Nc2nc(Cl)ncc2Cl)n1>>CC1(C)CCC(=O)Nc2ccc(Nc3ncc(Cl)c(Nc4ccccc4-c4nc(C(F)(F)F)c[nH]4)n3)cc21 -US06046214,6,COC(=O)C1=CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC=C(C(=O)O)C1 -US20050222176A1,1,Clc1cc2c(NC3CCNCC3)ncnc2s1.N#Cc1cc(C=O)ccc1F>>N#Cc1cc(CN2CCC(Nc3ncnc4sc(Cl)cc34)CC2)ccc1F -US20100069351A1,1,Cc1nsc(-c2ccc(Cl)nn2)n1.c1ccc2c(c1)CC1(CCNCC1)O2>>Cc1nsc(-c2ccc(N3CCC4(CC3)Cc3ccccc3O4)nn2)n1 -US20080181866A1,6,CC(C)(C)OC(=O)N1[C@H](C(=O)Nc2nc(-c3ccc(C(=O)NC4CC4)cc3)cs2)CC[C@@H]1c1ccccc1>>O=C(NC1CC1)c1ccc(-c2csc(NC(=O)[C@@H]3CC[C@H](c4ccccc4)N3)n2)cc1 -US20040192688A1,1,ClCCCOc1ccc2ccccc2c1.NC1CCCCC1>>c1ccc2cc(OCCCNC3CCCCC3)ccc2c1 -US07514567B2,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=C1OC2(CN3CCC2CC3)CN1c1ncc(Br)s1>>O=C1OC2(CN3CCC2CC3)CN1c1ncc(-c2ccccn2)s1 -US04086238,1,C#CCN.COCC(Cl)C=O>>C#CCNC(C=O)COC -US20150239884A1,3,Cc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(Cl)c2n1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(-c3cnn(C)c3)c2n1 -US20070142450A1,2,Nc1cc(Cl)ccc1O.O=C=Nc1cc(C(F)(F)F)ccc1Cl>>O=C(Nc1cc(Cl)ccc1O)Nc1cc(C(F)(F)F)ccc1Cl -US20120309739A1,6,COc1nc(N2CCC(O)CC2)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c12>>COc1nc(N2CCC(O)CC2)nc2oc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)c12 -US09067937B2,1,CC(=O)c1cnc2ccc(Cl)nc2c1Cl.CN(C)C[C@@H]1CC[C@@H](N)CC1>>CC(=O)c1cnc2ccc(Cl)nc2c1N[C@@H]1CC[C@@H](CN(C)C)CC1 -US20120101083A1,2,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCCC(=O)O)CC4)no2)cc1C#N.CN>>CNC(=O)CCCN1CCc2ccc(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cc2CC1 -US20130165464A1,6,COC(=O)c1cn(-c2ccnc(NCCc3ccc(O)cc3)n2)nc1-c1ccccc1Cl>>O=C(O)c1cn(-c2ccnc(NCCc3ccc(O)cc3)n2)nc1-c1ccccc1Cl -US08338437B2,1,COc1ccccc1CCO.N#Cc1cccc(-n2nc(C(F)(F)F)cc2O)c1>>COc1ccccc1CCOc1cc(C(F)(F)F)nn1-c1cccc(C#N)c1 -US20060281778A1,2,CC(C)(C)c1ccc2nc3sc(C(=O)O)cc3cc2c1.[N-]=[N+]=NCC(N)c1ccccc1>>CC(C)(C)c1ccc2nc3sc(C(=O)N[C@H](CN=[N+]=[N-])c4ccccc4)cc3cc2c1 -US20140128617A1,2,CC(C)C1C2CCC1c1c(N)cccc12.CCOC(=O)c1cn(C)nc1C(F)F>>CC(C)C1C2CCC1c1c(NC(=O)c3cn(C)nc3C(F)F)cccc12 -US04411903,6,CCOC(=O)CNC(=O)c1ccc(NCCCCCCCCCCCCCCCCBr)cc1>>O=C(O)CNC(=O)c1ccc(NCCCCCCCCCCCCCCCCBr)cc1 -US06441023B1,6,CCOC(=O)C1(S(=O)(=O)c2ccc(OC)cc2)CCN(CC=C(C)C)CC1>>COc1ccc(S(=O)(=O)C2(C(=O)O)CCN(CC=C(C)C)CC2)cc1 -US20080119459A1,2,Nc1ccc(Cl)c(Cl)c1.O=C(Cl)c1cc(C(F)(F)F)cc([N+](=O)[O-])c1Cl>>O=C(Nc1ccc(Cl)c(Cl)c1)c1cc(C(F)(F)F)cc([N+](=O)[O-])c1Cl -US04540815,2,CC(=O)[O-].CCCOc1ccc(N)cc1N>>CCCOc1ccc(NC(C)=O)cc1N -US20150239837A1,2,CC(C)(C)OC(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21.NCc1cccc(Cl)c1F>>CC(C)(C)OC(=O)N1[C@H](C(=O)NCc2cccc(Cl)c2F)C[C@@H]2CCCC[C@@H]21 -US05270327,7,O=C(C1CSCCN1)N1CCCC1>>C1CCN(CC2CSCCN2)C1 -US20120165306A1,1,Clc1cncc(Cl)n1.NCC1CCOCC1>>Clc1cncc(NCC2CCOCC2)n1 -US20040077646A1,2,N#CCNC(=O)C1CCCCC1N.O=C(O)c1cc2ccc(Cl)cc2[nH]1>>N#CCNC(=O)C1CCCCC1NC(=O)c1cc2ccc(Cl)cc2[nH]1 -US20120251545A1,1,BrCc1ccccc1.COC(=O)c1ccc(O)c(Br)c1>>COC(=O)c1ccc(OCc2ccccc2)c(Br)c1 -US08735414B2,6,COC(=O)c1c(-c2ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)n(C2CCCC2)c2cc(C)c(F)cc12>>Cc1cc2c(cc1F)c(C(=O)O)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCCC1 -US04724199,2,Nc1ccc(NNC=O)cc1.O=C(O)c1cccc(-n2nnnc2S)c1>>O=CNNc1ccc(NC(=O)c2cccc(-n3nnnc3S)c2)cc1 -US20090111791A1,2,O=C=NCc1ccc(Cl)cc1Cl.c1cnc(OC2CCCNC2)nc1>>O=C(NCc1ccc(Cl)cc1Cl)N1CCCC(Oc2ncccn2)C1 -US20140336177A1,3,CC(C)(C)OC(=O)C[Zn+].Nc1ncc(Br)cc1F>>CC(C)(C)OC(=O)Cc1cnc(N)c(F)c1 -US07579347B2,2,CC(C)(C)c1ccc(/C=C/C(=O)O)cc1.Nc1cccc(O)c1>>CC(C)(C)c1ccc(/C=C/C(=O)Nc2cccc(O)c2)cc1 -US20090227799A1,2,NCc1ccc(Oc2ccccc2)s1.Nc1nc(Cl)ccc1C(=O)O>>Nc1nc(Cl)ccc1C(=O)NCc1ccc(Oc2ccccc2)s1 -US04334077,1,C=[N+]=[N-].O=C(O)c1ccc2c(c1)Sc1ccc(F)cc1C(O)=C2>>COC(=O)c1ccc2c(c1)Sc1ccc(F)cc1C(O)=C2 -US04680402,1,CC1CCNCC1.O=C(c1ccccc1Cl)c1cc([N+](=O)[O-])ccc1Cl>>CC1CCN(c2ccc([N+](=O)[O-])cc2C(=O)c2ccccc2Cl)CC1 -US20060122195A1,1,COC(=O)[C@H](N)CS.COc1nc(Cl)cnc1N(COCC[Si](C)(C)C)S(=O)(=O)c1cccc(Cl)c1Cl>>COC(=O)[C@H](N)CSc1cnc(N(COCC[Si](C)(C)C)S(=O)(=O)c2cccc(Cl)c2Cl)c(OC)n1 -US20020169171A1,9,O=C(O)c1nc(-c2ccccc2)ncc1Br.[NH4+]>>Nc1cnc(-c2ccccc2)nc1C(=O)O -US20080076758A1,7,O=[N+]([O-])c1cccc2[nH]ncc12>>Nc1cccc2[nH]ncc12 -US20090149445A1,7,O=[N+]([O-])c1cc(Br)ccc1NCCN1CCOCC1>>Nc1cc(Br)ccc1NCCN1CCOCC1 -US20100143299A1,4,NC=O.Nc1ccc(Br)cc1C(=O)O>>O=c1[nH]cnc2ccc(Br)cc12 -US08729268B2,1,COCCOCCN.O=Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1>>COCCOCCNCc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1 -US20140349993A1,2,Nc1cccc(CN2CCOCC2)n1.O=C(O)c1cnc2ccc(-c3ccccc3C(F)(F)F)nn12>>O=C(Nc1cccc(CN2CCOCC2)n1)c1cnc2ccc(-c3ccccc3C(F)(F)F)nn12 -US07645785B2,2,CC(=O)OC(C)=O.Nc1ccc(-c2nc3ccccc3n2C(C(=O)NC2CCCCC2)C2CCCCC2)cc1>>CC(=O)Nc1ccc(-c2nc3ccccc3n2C(C(=O)NC2CCCCC2)C2CCCCC2)cc1 -US20150239866A1,3,C#C[Si](C)(C)C.COC(=O)C1CCC(=O)CC1(C)C>>COC(=O)C1CCC(O)(C#C[Si](C)(C)C)CC1(C)C -US20050090559A1,1,CC(C)(CC(O)(C=O)C(F)(F)F)c1cc(F)ccc1F.Nc1cccc2[nH]ncc12>>CC(C)(CC(O)(C=Nc1cccc2[nH]ncc12)C(F)(F)F)c1cc(F)ccc1F -US20060178510A1,6,CC(C)(C)OC(=O)N1CCO[C@H](Cc2cc(Br)ccc2O)C1>>Oc1ccc(Br)cc1C[C@@H]1CNCCO1 -US20150045368A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H]([NH3+])c1ccccc1C>>COC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1C -US05157121,2,CCOC(=O)NS(=O)(=O)N(C)S(C)(=O)=O.COc1cc(C)nc(N)n1>>COc1cc(C)nc(NC(=O)NS(=O)(=O)N(C)S(C)(=O)=O)n1 -US05599819,3,C#C[Si](C)(C)C.CC1(C)CC(C)(C)c2cc(Br)ccc2S1>>CC1(C)CC(C)(C)c2cc(C#C[Si](C)(C)C)ccc2S1 -US05200422,2,CC(=O)Cl.Nc1ccc2oc(=O)[nH]c2c1>>CC(=O)Nc1ccc2oc(=O)[nH]c2c1 -US07312358B2,1,CN(C)CCCO.O=S(=O)(Nc1ccc(Cl)cc1)c1ccc(F)cc1>>CN(C)CCCOc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1 -US07557127B2,1,C1CCNC1.O=[N+]([O-])c1ccccc1CBr>>O=[N+]([O-])c1ccccc1CN1CCCC1 -US06967216B2,3,CC(=O)c1ccncc1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=C(C)c1ccncc1 -US20100184809A1,7,COC(=O)c1cccc(CN(C)c2ncc([N+](=O)[O-])cc2Cl)c1>>COC(=O)c1cccc(CN(C)c2ncc(N)cc2Cl)c1 -US20090318500A1,6,CC(C)(C)OC(=O)N1CCC(NC(=O)c2n[nH]cc2[N+](=O)[O-])CC1>>O=C(NC1CCNCC1)c1n[nH]cc1[N+](=O)[O-] -US09150592B2,3,CB1OB(C)OB(C)O1.COc1cc(C=O)c(Br)cc1Cl>>COc1cc(C=O)c(C)cc1Cl -US20080194608A1,3,C=CCCC(Oc1ccccc1OC)C(=O)OCC.COc1ccc(O)c(Br)c1>>CCOC(=O)C(CCC=Cc1cc(OC)ccc1O)Oc1ccccc1OC -US08354444B2,7,O=[N+]([O-])c1ccc(-c2ncn[nH]2)cc1>>Nc1ccc(-c2ncn[nH]2)cc1 -US20100120775A1,6,CCOC(=O)c1ccc2cc(-c3ccc(SCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)ccc2n1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CSc1ccc(-c2ccc3nc(C(=O)O)ccc3c2)cc1 -US04698348,1,C[O-].OCC(O)Cn1cnc2c(Cl)nc3ccccc3c21>>COc1nc2ccccc2c2c1ncn2CC(O)CO -US20140088081A1,2,CS(=O)(=O)Cl.C[C@H](O)c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1>>C[C@H](OS(C)(=O)=O)c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1 -US05219871,6,CN(CCCC(C(N)=O)(c1ccccc1)c1ccccc1)Cc1ccccc1>>CNCCCC(C(N)=O)(c1ccccc1)c1ccccc1 -US04748183,2,Nc1nnn[nH]1.O=C(O)c1ccco1>>O=C(Nc1nnn[nH]1)c1ccco1 -US20060189625A1,1,COc1cc(F)c(Br)cc1F.c1ccc(CCCC2CCNCC2)cc1>>COc1cc(F)c(N2CCC(CCCc3ccccc3)CC2)cc1F -US20050182040A1,1,C=O.COc1cc(NC2CCN(Cc3ccccc3)CC2)ccc1C(N)=O>>COc1cc(N(C)C2CCN(Cc3ccccc3)CC2)ccc1C(N)=O -US20100272680A1,2,COC(=O)c1nc2c(C(F)(F)F)cc(OC)cn2c1Cl.O=C1OCCN1C1CCNCC1>>COc1cc(C(F)(F)F)c2nc(C(=O)N3CCC(N4CCOC4=O)CC3)c(Cl)n2c1 -US20080171771A1,3,NC1=NC(c2ccc(C(F)(F)F)nc2)(c2cccc(Br)c2)c2ccccc21.OB(O)c1cncnc1>>NC1=NC(c2ccc(C(F)(F)F)nc2)(c2cccc(-c3cncnc3)c2)c2ccccc21 -US05091409,7,CCCC1CC(NC(C)=O)c2cc(S(N)(=O)=O)sc2S1(=O)=O>>CCC[C@H]1C[C@H](NCC)c2cc(S(N)(=O)=O)sc2S1(=O)=O -US07452992B2,8,CC(C)(C)NS(=O)(=O)c1cc(C(=O)N2CCC(CCO)(c3ccccc3)OC2)c(Cl)cc1F>>CC(C)(C)NS(=O)(=O)c1cc(C(=O)N2CCC(CC=O)(c3ccccc3)OC2)c(Cl)cc1F -US20120270865A2,3,O=Cc1csc2ccccc12.[Mg+]C1CCCCC1>>OC(c1csc2ccccc12)C1CCCCC1 -US20110098323A1,3,CCOc1cc(C=O)ccc1O.O=C1CSC(=S)N1c1cccc(F)c1>>CCOc1cc(C=C2SC(=S)N(c3cccc(F)c3)C2=O)ccc1O -US20110009454A1,2,NCc1cccc(OCCc2ccccc2)c1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1cccc(OCCc2ccccc2)c1 -US07667043B2,2,CCOC(=O)c1ccc(Br)cc1.NN>>NNC(=O)c1ccc(Br)cc1 -US20100004245A1,6,CCOC(=O)c1cncc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nc2)c1>>O=C(O)c1cncc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nc2)c1 -US20130267482A1,6,CCOC(=O)CN(C)NC(=O)NCc1cccs1>>CN(CC(=O)O)NC(=O)NCc1cccs1 -US04871389,1,CC#CC(O)(c1ccc(Cl)cc1Cl)C(C)Br.c1nc[nH]n1>>CC#CC(O)(c1ccc(Cl)cc1Cl)C(C)n1cncn1 -US20070111998A1,2,Cc1cnc(N)s1.O=C(Br)CBr>>Cc1cnc(NC(=O)CBr)s1 -US20120258950A1,2,CC(C)n1cc(C(=O)c2cncc(N)c2)c2cncnc21.O=C(O)C(OC1CCCCO1)c1ccccc1>>CC(C)n1cc(C(=O)c2cncc(NC(=O)C(OC3CCCCO3)c3ccccc3)c2)c2cncnc21 -US06235096B1,2,CC(=O)O.Cc1c(Cl)cc(N)c(O)c1Cl>>CC(=O)Nc1cc(Cl)c(C)c(Cl)c1O -US20150203511A1,10,Cc1c(-n2nnn(C)c2=O)cccc1[N+](=O)[O-].O=C1CCC(=O)N1Br>>Cn1nnn(-c2cccc([N+](=O)[O-])c2CBr)c1=O -US05593982,7,C[C@]12CCC(=O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccoc3)C[C@H]3O[C@@]312>>C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccoc3)C[C@H]3O[C@@]312 -US20040092737A1,8,COCN1c2cc(CO)c(OC)cc2Oc2nccnc21>>COCN1c2cc(C=O)c(OC)cc2Oc2nccnc21 -US20110046406A1,7,CCOC(=O)C(F)(F)CC1CC1>>OCC(F)(F)CC1CC1 -US20070259851A1,6,CC(C)(C)OC(=O)N1CCC(n2cc(C#N)[nH]c2=O)CC1>>N#Cc1cn(C2CCNCC2)c(=O)[nH]1 -US20140023614A1,2,CC(C)(C)OC(=O)N1CCCC(CO)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCCC(COS(C)(=O)=O)C1 -US07671073B2,7,C[C@@H](C1CC=C(c2cccc3ncnn23)CC1)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(F)(F)C1>>C[C@@H](C1CCC(c2cccc3ncnn23)CC1)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(F)(F)C1 -US20070244173A1,1,COCCO.Cn1c(C2CC2)nc2c3c(ccc21)[C@@H](O)[C@H](O)[C@@H](c1ccccc1)O3>>COCCO[C@@H]1c2ccc3c(nc(C4CC4)n3C)c2O[C@H](c2ccccc2)[C@H]1O -US20090192138A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cn1c(=O)[nH]c(=O)c2c1c(C#N)c(Br)n2Cc1ccccc1>>Cn1c(=O)[nH]c(=O)c2c1c(C#N)c(N1CCN(C(=O)OC(C)(C)C)CC1)n2Cc1ccccc1 -US20150218170A1,1,CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12.Cn1ccc(N)n1>>Cn1ccc(Nc2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)n1 -US08809538B2,1,CCI.CCOc1ccc(C(=O)O)c(OCC)n1>>CCOC(=O)c1ccc(OCC)nc1OCC -US04902794,7,CCCCC(=O)OC(=O)CCCC>>CCCCC(=O)O -US20100216795A1,2,COCCOc1ccc(C(=O)O)cc1[N+](=O)[O-].NC(=O)c1nc(Nc2ccnc(F)c2)sc1N>>COCCOc1ccc(C(=O)Nc2sc(Nc3ccnc(F)c3)nc2C(N)=O)cc1[N+](=O)[O-] -US20050245503A1,9,NC1c2ccccc2CCc2ccccc21.S=C=S>>S=C=NC1c2ccccc2CCc2ccccc21 -US05834486,1,CC(C)(C)OC(=O)NCCCN(CCc1ccccn1)C(=O)OC(C)(C)C.CCN(CCCBr)C(=O)OC(C)(C)C>>CCN(CCCN(CCCN(CCc1ccccn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US20090076070A1,1,N#Cc1cccc2[nH]ccc12.NC(=O)CBr>>N#Cc1cccc2c1ccn2CC(N)=O -US05736534,1,CN(C)CCCCl.Nc1ccc2ncnc(N3CCc4ccc(Cl)cc43)c2c1>>CN(C)CCCNc1ccc2ncnc(N3CCc4ccc(Cl)cc43)c2c1 -US20100087424A1,3,C=CC(=O)OCCCC.COc1ccc2ccc(F)c(Br)c2n1>>CCCCOC(=O)/C=C/c1c(F)ccc2ccc(OC)nc12 -US06271234B1,2,CC(=O)Cl.COc1cc(N)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1>>COc1cc(NC(C)=O)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 -US08138197B2,6,CCOc1cc(C(=O)OC)cc(OC)c1-c1cnn(C)c1>>CCOc1cc(C(=O)O)cc(OC)c1-c1cnn(C)c1 -US08357687B2,1,COC(=O)CBr.Cn1c(-c2ccccc2O)c(C2CCCCC2)c2ccc(C(=O)OC(C)(C)C)cc21>>COC(=O)COc1ccccc1-c1c(C2CCCCC2)c2ccc(C(=O)OC(C)(C)C)cc2n1C -US06277871B1,1,NCc1ccccc1.O=Cc1nccs1>>c1ccc(CNCc2nccs2)cc1 -US09090599B2,2,CCc1cc(CN)on1.O=C(O)c1cc(-c2ccc(Cl)cc2)c(OCC(F)(F)F)cn1>>CCc1cc(CNC(=O)c2cc(-c3ccc(Cl)cc3)c(OCC(F)(F)F)cn2)on1 -US20060217380A1,3,C#C[Si](C)(C)C.CNc1ncc(Br)cn1>>CNc1ncc(C#C[Si](C)(C)C)cn1 -US20030096856A1,6,COCCN(CCOC)CC(=O)OCc1ccccc1>>COCCN(CCOC)CC(=O)O -US04014887,1,CC1(C)CC(O)CC(C)(C)N1.CCCCCCCCCCCCBr>>CCCCCCCCCCCCN1C(C)(C)CC(O)CC1(C)C -US05500424,6,CCOC(=O)c1cnc(-c2ccccc2)nc1-c1ccccc1Cl>>O=C(O)c1cnc(-c2ccccc2)nc1-c1ccccc1Cl -US20090163471A1,9,COC(=O)c1ccc(Br)cc1F.[C-]#N>>COC(=O)c1ccc(C#N)cc1F -US20110260138A1,1,Brc1ccccc1.c1ccc2c(c1)[nH]c1ccccc12>>c1ccc(-n2c3ccccc3c3ccccc32)cc1 -US08129376B2,2,NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1.O=C(O)c1cc(-c2cccnc2)[nH]n1>>O=C(NCC(=O)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1)c1cc(-c2cccnc2)[nH]n1 -US07173043B2,1,BrCCCCBr.Oc1ccc2c(-c3ccc(F)cc3)csc2c1>>Fc1ccc(-c2csc3cc(OCCCCBr)ccc23)cc1 -US20100137313A1,3,CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1.Cc1cc(C(F)(F)F)nn1-c1nc(Nc2cccc(Cl)c2)ncc1Br>>CCOC(=O)c1cncc(-c2cnc(Nc3cccc(Cl)c3)nc2-n2nc(C(F)(F)F)cc2C)c1 -US05756497,7,O=C1CCCc2ncccc21>>OC1CCCc2ncccc21 -US06046210,2,COc1ccc2c(c1)CN(CCCCN)CC2.N#Cc1cccc(-c2ccc(C(=O)O)cc2)c1>>COc1ccc2c(c1)CN(CCCCNC(=O)c1ccc(-c3cccc(C#N)c3)cc1)CC2 -US20140005195A1,7,CCN(CC)CCOc1cc(C#N)nc(-c2ccccn2)c1>>CCN(CC)CCOc1cc(CN)nc(-c2ccccn2)c1 -US20120022075A1,2,COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc(-c2ccc(C(=O)O)[nH]2)c1.C[C@H](O)[C@@H](N)CO>>COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc(-c2ccc(C(=O)N[C@@H](CO)[C@H](C)O)[nH]2)c1 -US08067511B2,1,CI.Oc1ccc2ccccc2c1Br>>COc1ccc2ccccc2c1Br -US05192760,1,CCOC(=O)Nc1ccc2c(c1)N(C(=O)C(C)Br)c1ccccc1C=C2.CN>>CCOC(=O)Nc1ccc2c(c1)N(C(=O)C(C)NC)c1ccccc1C=C2 -US20090215754A1,1,CN(C)CCCCl.NS(=O)(=O)c1cc(C(=O)O)cc(N2CCCC2)c1Oc1ccccc1>>CN(C)CCCOC(=O)c1cc(N2CCCC2)c(Oc2ccccc2)c(S(N)(=O)=O)c1 -US20100160373A1,3,CB1OB(C)OB(C)O1.CN1C(=O)CCc2cc(Br)c(N)cc21>>Cc1cc2c(cc1N)N(C)C(=O)CC2 -US07488731B2,2,CN(C)c1cccc(N2CCN(CCCCN)CC2)c1.O=S(=O)(Cl)CC1CCCCC1>>CN(C)c1cccc(N2CCN(CCCCNS(=O)(=O)CC3CCCCC3)CC2)c1 -US20020052322A1,2,COC(=O)[C@@H](N)C(C)C.C[C@H](NC(=O)Cc1ccccc1)C(=O)O>>COC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)Cc1ccccc1)C(C)C -US20150111892A1,6,CCCCCCNC(=O)n1cc(CO[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O>>CCCCCCNC(=O)n1cc(CO)c(=O)n(C)c1=O -US08063099B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c1.O=C(O)c1cc(F)cc2c1OCOC2>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2cc(F)cc3c2OCOC3)c1 -US08445480B2,7,C/C=C(/C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4CCN(c5nccc(C(F)(F)F)n5)CC4)cc3)oc12>>CCC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4CCN(c5nccc(C(F)(F)F)n5)CC4)cc3)oc12 -US20040014802A1,2,Nc1n[nH]c2cc(Cl)ccc12.O=C(Cl)Cc1cccs1>>O=C(Cc1cccs1)Nc1n[nH]c2cc(Cl)ccc12 -US04728646,1,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3c(NCc4ccco4)ncnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3c(NCc4ccco4)ncnc23)CC1 -US20030236250A1,6,COC(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(C)(C(=O)O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US07151118B2,2,CN1CCNCC1.Cc1ccc(NC(=O)c2ccnc(N3CCCC3)c2)cc1-c1ccc(C(=O)O)cc1>>Cc1ccc(NC(=O)c2ccnc(N3CCCC3)c2)cc1-c1ccc(C(=O)N2CCN(C)CC2)cc1 -US05663162,7,CCOC(=O)c1csc2cncn12>>OCc1csc2cncn12 -US20140140956A1,3,CC(C)(C)[Si](C)(C)OCCOc1ccc(C=O)cc1Br.CC1(C)OB(c2ccc(S(C)(=O)=O)cc2)OC1(C)C>>CC(C)(C)[Si](C)(C)OCCOc1ccc(C=O)cc1-c1ccc(S(C)(=O)=O)cc1 -US20090264431A1,2,CC(C)(C)C(=O)Cl.CC(C)(C)OC(=O)N1C[C@H](NS(=O)(=O)c2cc(Br)ccc2Br)C[C@@H]1CN>>CC(C)(C)OC(=O)N1C[C@H](NS(=O)(=O)c2cc(Br)ccc2Br)C[C@@H]1CNC(=O)C(C)(C)C -US20090192190A1,1,Cc1c(I)cc(C(C)(C)C)c(O)c1C(=O)O.SCc1ccccc1>>Cc1c(SCc2ccccc2)cc(C(C)(C)C)c(O)c1C(=O)O -US08217032B2,1,Oc1ccc2c(C(O)c3ccc(OCCN4CCCCC4)cc3)c(-c3c(F)cc(F)cc3F)ccc2c1>>Oc1ccc2c3c(ccc2c1)-c1c(F)cc(F)cc1OC3c1ccc(OCCN2CCCCC2)cc1 -US05716954,3,CCCCN1C(=O)c2cccnc2C1=O.[Mg+]c1ccccc1>>CCCCN1C(=O)c2cccnc2C1(O)c1ccccc1 -US20110166132A1,1,C1CCNCC1.Cc1cc(-c2ccc(NC(=O)C(C)c3ccc(Cl)nc3)cc2)ccn1>>Cc1cc(-c2ccc(NC(=O)C(C)c3ccc(N4CCCCC4)nc3)cc2)ccn1 -US07582626B2,1,NS(=O)(=O)Cc1ccccc1.O=C1C(C2=NS(=O)(=O)c3cc(I)ccc3N2)=C(O)[C@@H]2CCC[C@@H]2N1Cc1ccc(F)cc1>>O=C1C(C2=NS(=O)(=O)c3cc(NS(=O)(=O)Cc4ccccc4)ccc3N2)=C(O)[C@@H]2CCC[C@@H]2N1Cc1ccc(F)cc1 -US20050245519A1,1,CC(C)(C)OC(=O)N1CCOC(C(Oc2ccccc2CO)c2ccccc2)C1.CI>>COCc1ccccc1OC(c1ccccc1)C1CN(C(=O)OC(C)(C)C)CCO1 -US20020025948A1,2,C=CCN1CC2C(C1)C2(CC)c1cccc(N)c1.CS(=O)(=O)Cl>>C=CCN1CC2C(C1)C2(CC)c1cccc(NS(C)(=O)=O)c1 -US20060105997A1,8,COC(=O)C(C)(C)CO>>COC(=O)C(C)(C)C=O -US20060287309A1,1,CCc1c(F)cccc1N1CCNCC1.O=CCCCOc1ccc2c(n1)NC(=O)CC2>>CCc1c(F)cccc1N1CCN(CCCCOc2ccc3c(n2)NC(=O)CC3)CC1 -US06384051B1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Cc1ccc(N)cc1Br>>COc1cc2ncc(C#N)c(Nc3ccc(C)c(Br)c3)c2cc1OC -US06794402B2,1,CC=O.C[C@@H](CCc1ccccc1)N[C@@H]1CC[C@@H](c2ccc3[nH]c(=O)oc3c2)CC1>>CCN([C@@H](C)CCc1ccccc1)[C@@H]1CC[C@@H](c2ccc3[nH]c(=O)oc3c2)CC1 -US03985750,2,CCCCCCCCCCCC(=O)Cl.COc1ccc2c(c1)C(N1CCN(CCCO)CC1)Cc1ccccc1S2>>CCCCCCCCCCCC(=O)OCCCN1CCN(C2Cc3ccccc3Sc3ccc(OC)cc32)CC1 -US20110028467A1,2,COc1c(Br)cc(C(=O)Cl)cc1Br.N#Cc1ccc(-c2cnc3c(c2)NCCO3)cc1>>COc1c(Br)cc(C(=O)N2CCOc3ncc(-c4ccc(C#N)cc4)cc32)cc1Br -US04152329,2,CC(C)(C)c1nnc(NC(=O)Cc2csc(N)n2)s1.CN=C=O>>CNC(=O)Nc1nc(CC(=O)Nc2nnc(C(C)(C)C)s2)cs1 -US06949542B2,2,Cc1cc(N)c(NC(=O)OC(C)(C)C)cc1Cl.Cc1cncc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)n1>>Cc1cncc(-c2cccc(C(=O)CC(=O)Nc3cc(C)c(Cl)cc3NC(=O)OC(C)(C)C)c2)n1 -US20060211695A1,7,Cc1c(OC(=O)C(C)(C)C)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12>>Cc1c(O)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12 -US20040030129A1,2,C1CSCCN1.COC1=C(OC)C(=O)C(Cc2cccc(CCC(=O)O)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2cccc(CCC(=O)N3CCSCC3)c2)=C(C)C1=O -US20090325936A1,3,O=C(NC12CC3CC(CC(C3)C1)C2)c1nc(Br)n2ccccc12.OB(O)c1cccnc1>>O=C(NC12CC3CC(CC(C3)C1)C2)c1nc(-c2cccnc2)n2ccccc12 -US08658641B2,2,CC(C)(C)CN.CCOC(=O)c1noc2c(Cl)c(N3C[C@H](C)O[C@H](C)C3)c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)nc12>>C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)nc3c(C(=O)NCC(C)(C)C)noc3c2Cl)C[C@@H](C)O1 -US20040248920A1,9,CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)[C@]12CN(CC(=O)O)C[C@H]2c1ccc(C#N)cc1.N>>CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)[C@]12CN(CC(N)=O)C[C@H]2c1ccc(C#N)cc1 -US20120220603A1,2,O=C(O)CNc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C1CNCCN1>>O=C1CN(C(=O)CNc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCN1 -US07960369B2,1,Cc1cccc(C)c1O.O=Cc1cccc(Br)c1>>Cc1cccc(C)c1Oc1cccc(C=O)c1 -US20110028467A1,3,Brc1cnc2c(c1)NCCO2.OB(O)c1ccccc1C(F)(F)F>>FC(F)(F)c1ccccc1-c1cnc2c(c1)NCCO2 -US20030105151A1,3,COC(=O)c1ccc2c(c1)CC(=O)N2.Cc1c(CCC(=O)O)c[nH]c1C=O>>COC(=O)c1ccc2c(c1)C(=Cc1[nH]cc(CCC(=O)O)c1C)C(=O)N2 -US05747489,2,CCC1SC(=O)N(Cc2ccc(N)cc2)N=C1c1ccc(OC)c(OC)c1.O=C(Cl)C(F)(F)F>>CCC1SC(=O)N(Cc2ccc(NC(=O)C(F)(F)F)cc2)N=C1c1ccc(OC)c(OC)c1 -US20100113435A1,2,CCOC(=O)C(=O)c1csc(N)n1.Cc1c(Cl)cccc1S(=O)(=O)Cl>>CCOC(=O)C(=O)c1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1 -US05597818,7,CN1C(=O)[C@H](NC(=O)CCc2ccc(Cl)cc2Cl)N=C(c2ccccc2)c2cc([N+](=O)[O-])ccc21>>CN1C(=O)[C@H](NC(=O)CCc2ccc(Cl)cc2Cl)N=C(c2ccccc2)c2cc(N)ccc21 -US20100120785A1,6,CCOc1ccc(-c2nccnc2N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CCOc1ccc(-c2nccnc2N2CCNCC2)cc1 -US20080033049A1,6,COc1ccc(-c2ccc(C=O)c(Cl)c2)cc1F>>O=Cc1ccc(-c2ccc(O)c(F)c2)cc1Cl -US06326503B1,1,CC[Si](CC)(CC)OC(C)(C)C#CCBr.C[C@@H](O)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CC[Si](CC)(CC)OC(C)(C)C#CCO[C@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C -US20120128630A1,1,CO.Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(C)nn3)C2c2ccc(C(C)C)cc2)cc1>>COC1=C(C(=O)c2ccc(C)cc2)C(c2ccc(C(C)C)cc2)N(c2ccc(C)nn2)C1=O -US05998665,1,CN.Nc1ccc(S(=O)(=O)Nc2cc(Br)nc(Br)c2)cc1>>CNc1cc(NS(=O)(=O)c2ccc(N)cc2)cc(Br)n1 -US20090105266A1,1,CCCN.O=[N+]([O-])c1cc(C(F)(F)F)ccc1Cl>>CCCNc1ccc(C(F)(F)F)cc1[N+](=O)[O-] -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CN(C(=O)C2CNC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(Cl)c1ccccc1>>CN(C(=O)N(C)[C@@H]1CN(C(=O)C2CN(C(=O)c3ccccc3)C2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20030176454A1,6,Cc1ncccc1Oc1ccc(NC(=S)NC(=O)c2ccccc2)cn1>>Cc1ncccc1Oc1ccc(NC(N)=S)cn1 -US08673911B2,7,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1N -US07365085B2,1,BrCCCBr.FC(F)(F)c1cccc(CNCC(c2ccccc2)c2ccccc2)c1Cl>>FC(F)(F)c1cccc(CN(CCCBr)CC(c2ccccc2)c2ccccc2)c1Cl -US07151112B1,1,O=C(Nc1ccc(F)cc1)c1ccc(Cl)nc1.O=C(O)CCS>>O=C(O)CCSc1ccc(C(=O)Nc2ccc(F)cc2)cn1 -US05486525,7,Nc1cc(Cl)ccc1[N+](=O)[O-]>>Nc1ccc(Cl)cc1N -US20120214803A1,7,Cc1cc([N+](=O)[O-])c2ncccc2c1Cl>>Cc1cc(N)c2ncccc2c1Cl -US20130040930A1,6,COc1ccc(CN2CC(C)N(c3ccc(C(=O)N4CCN(c5ncc(C)cc5C)CC4)cc3F)C2=O)cc1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)NCC4C)c(F)c3)CC2)c(C)c1 -US04113464,2,C#CC(C)(C)NCC1OC(C)C(C)O1.CC(Br)C(=O)Cl>>C#CC(C)(C)N(CC1OC(C)C(C)O1)C(=O)C(C)Br -US06359138B1,7,Cc1ccc(CC2(O)CCN(CC3=Cc4ccc(O)cc4C3)CC2)cc1>>Cc1ccc(CC2(O)CCN(CC3Cc4ccc(O)cc4C3)CC2)cc1 -US09045486B2,6,CC(C)(C)OC(=O)c1nc(CC2(c3cc(Cl)ccc3Cl)CCCC2)nc(O)c1OCc1ccccc1>>O=C(O)c1nc(CC2(c3cc(Cl)ccc3Cl)CCCC2)nc(O)c1OCc1ccccc1 -US20100222345A1,7,Nc1cc(C(F)(F)F)c(Br)cc1[N+](=O)[O-]>>Nc1cc(Br)c(C(F)(F)F)cc1N -US06335459B1,1,CC(C)(C)OC(=O)CBr.Oc1cccc(Br)c1>>CC(C)(C)OC(=O)COc1cccc(Br)c1 -US20040248934A1,2,Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)O.Oc1ccc2c(c1)CCNC2>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)N1CCc2cc(O)ccc2C1 -US06693200B2,3,Cc1ccccc1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>Cc1ccc(C(=O)c2ccc([N+](=O)[O-])cc2)cc1 -US20150045339A1,1,C[O-].Clc1ncc(I)c(Cl)n1>>COc1nc(Cl)ncc1I -US20150011532A1,1,COc1cccc(-c2cnc(Cl)cc2NC(C)C)n1.Nc1ccc2ncsc2c1>>COc1cccc(-c2cnc(Nc3ccc4ncsc4c3)cc2NC(C)C)n1 -US20020049328A1,2,CC(C)(C)C(=O)Cl.C[C@@H](N)c1ccccc1>>C[C@@H](NC(=O)C(C)(C)C)c1ccccc1 -US20100056490A1,3,CN(C)C=O.COc1cc(Br)cc(C(C)C)c1>>COc1cc(C=O)cc(C(C)C)c1 -US20150057295A1,2,CC(C(=O)O)N(C)C(=O)OC(C)(C)C.CC(C)[Si](C#Cc1cc(Br)cc(N)n1)(C(C)C)C(C)C>>CC(C(=O)Nc1cc(Br)cc(C#C[Si](C(C)C)(C(C)C)C(C)C)n1)N(C)C(=O)OC(C)(C)C -US20120270875A1,1,CCOC(=O)c1c(C)nc(Cl)nc1C.COc1ccc2c(c1)CCC(N)C2>>CCOC(=O)c1c(C)nc(NC2CCc3cc(OC)ccc3C2)nc1C -US07241785B2,8,COc1cc(COc2cc(CO)n(-c3ccccc3)n2)ccc1OCc1nc(-c2ccco2)oc1C>>COc1cc(COc2cc(C=O)n(-c3ccccc3)n2)ccc1OCc1nc(-c2ccco2)oc1C -US20020161025A1,1,Fc1ccc(CCl)cc1.c1ccc2[nH]ccc2c1>>Fc1ccc(Cn2ccc3ccccc32)cc1 -US20150072980A1,1,CC1CCNCC1.COc1cc2c(cc1Br)C/C(=C\c1ccc(SC(F)(F)F)cc1)C2=O>>COc1cc2c(cc1N1CCC(C)CC1)C/C(=C\c1ccc(SC(F)(F)F)cc1)C2=O -US20120114765A1,2,Nc1ccc(F)cc1.O=C(Cl)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(Nc1ccc(F)cc1)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US07435744B2,1,Nc1ccc2c(c1)CCC(=O)N2.O=C(CCl)N1CCC(Cc2ccccc2)CC1>>O=C1CCc2cc(NCC(=O)N3CCC(Cc4ccccc4)CC3)ccc2N1 -US08354444B2,6,CC(C)(C)OC(=O)C1NC(CC2(CO)CC2)C(C#N)(c2ccc(Cl)cc2F)C1c1cccc(Cl)c1F>>N#CC1(c2ccc(Cl)cc2F)C(CC2(CO)CC2)NC(C(=O)O)C1c1cccc(Cl)c1F -US20100056497A1,2,CC(C)=CC(=O)O.COCCCOc1cc(C(=O)N(C(C)C)[C@@H]2CC[C@@H](CCNC3CC3)N(C(=O)OC(C)(C)C)C2)ccc1OC>>COCCCOc1cc(C(=O)N(C(C)C)[C@@H]2CC[C@H](CCN(C(=O)C=C(C)C)C3CC3)N(C(=O)OC(C)(C)C)C2)ccc1OC -US20150246922A1,3,O=C1NCCn2c1cc1cc(F)cc(Br)c12.OB(O)c1ccc(F)c(F)c1>>O=C1NCCn2c1cc1cc(F)cc(-c3ccc(F)c(F)c3)c12 -US20150272947A1,7,CCOC(=O)/C=C(\C)c1cccnc1>>CCOC(=O)CC(C)c1cccnc1 -US20120309735A1,7,CC(C)(C)[Si](OCCN(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)c1ncc(-c2cc(N3CCOCC3)cc([N+](=O)[O-])c2)s1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCCN(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)c1ncc(-c2cc(N)cc(N3CCOCC3)c2)s1)(c1ccccc1)c1ccccc1 -US07902252B2,6,CCCC1CCc2cc(C(=O)OC)[nH]c21>>CCCC1CCc2cc(C(=O)O)[nH]c21 -US20020198189A1,2,CC1NCCc2[nH]cnc21.O=C(Cl)COc1ccccc1>>CC1c2nc[nH]c2CCN1C(=O)COc1ccccc1 -US20090325989A1,1,Fc1cccc(Nc2ccc(Cl)cc2)n1.c1ccc2[nH]ncc2c1>>Clc1ccc(Nc2cccc(-n3ncc4ccccc43)n2)cc1 -US03931288,6,CCOC(=O)C1CCc2c(oc3cc(OC)ccc23)C1>>COc1ccc2c3c(oc2c1)CC(C(=O)O)CC3 -US20120040950A1,2,CCN.COc1ncc(Br)cc1C(=O)O>>CCNC(=O)c1cc(Br)cnc1OC -US20100004292A1,2,CC(C)(C)[Si](C)(C)OCCNc1ccc(N)cc1.O=C(Nc1cscc1C(=O)O)c1ccc(Cl)s1>>CC(C)(C)[Si](C)(C)OCCNc1ccc(NC(=O)c2cscc2NC(=O)c2ccc(Cl)s2)cc1 -US20130291227A1,2,CNc1cn(-c2cccnc2)nc1Cl.O=C(O)CCSC(c1ccccc1)(c1ccccc1)c1ccccc1>>CN(C(=O)CCSC(c1ccccc1)(c1ccccc1)c1ccccc1)c1cn(-c2cccnc2)nc1Cl -US20150018363A1,1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.Fc1cccc(CBr)c1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cccc(F)c4)cc3=O)cc21 -US20060045953A1,7,C=CCc1c(F)c(F)c(C(=O)N[C@@H](C)C(C)C)c(F)c1F>>CCCc1c(F)c(F)c(C(=O)N[C@@H](C)C(C)C)c(F)c1F -US08541449B2,6,CCC(NC(=O)OCc1ccccc1)C1(c2ccc(OC)cc2)CCC2(CC1)OCCO2>>CCC(NC(=O)OCc1ccccc1)C1(c2ccc(OC)cc2)CCC(=O)CC1 -US20070225377A1,1,BrCc1ccccc1.CCC(CC)(c1ccc(Br)cc1)c1ccc(O)c(C)c1>>CCC(CC)(c1ccc(Br)cc1)c1ccc(OCc2ccccc2)c(C)c1 -US06660753B2,3,C#CCO.N#Cc1cc(I)cc(-c2nc(-c3ccccn3)no2)c1>>N#Cc1cc(C#CCO)cc(-c2nc(-c3ccccn3)no2)c1 -US20100179139A1,2,NCCO.O=S(=O)(Cl)c1ccc(Br)s1>>O=S(=O)(NCCO)c1ccc(Br)s1 -US04304772,7,CN(C)C(=O)C1CC2CCC1c1c2c2ccccc2n1C>>CN(C)CC1CC2CCC1c1c2c2ccccc2n1C -US20070004776A1,1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.COC(=O)c1ccc(Cl)nc1>>COC(=O)c1ccc(Oc2ccc(CC(NC(=O)OC(C)(C)C)C(=O)O)cc2)nc1 -US20150065717A1,3,CN(C)C=O.FC(F)(F)Oc1cc(Br)ccc1I>>O=Cc1ccc(Br)cc1OC(F)(F)F -US20080227781A1,7,CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)C(=O)OC)cn1>>CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CO)cn1 -US04330548,6,CC(=O)SCC(=O)N1CC(=O)C[C@H]1C(=O)O>>O=C1C[C@@H](C(=O)O)N(C(=O)CS)C1 -US08809532B2,2,CC(=O)O.Cc1ccc(/C=C/c2cccc3c4c([nH]c23)CCNC4)cn1>>CC(=O)N1CCc2[nH]c3c(/C=C/c4ccc(C)nc4)cccc3c2C1 -US20040192728A1,1,CCCCCBr.COC(=O)c1ccc2[nH]ccc2c1>>CCCCCn1ccc2cc(C(=O)OC)ccc21 -US20030022893A1,6,COC(=O)Cc1cc(OC)c(OC)cc1S(=O)(=O)N1CCN(c2ccc(C(F)(F)F)cn2)CC1>>COc1cc(CC(=O)O)c(S(=O)(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cc1OC -US20110082164A1,3,CC1(C)OB(c2ccccc2F)OC1(C)C.CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cccc(Br)n4)cc3)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cccc(-c5ccccc5F)n4)cc3)cc2)CC1 -US20150148332A1,2,CC(C)=CC(=O)N=C=S.CNC>>CC(C)=CC(=O)NC(=S)N(C)C -US20120177681A1,1,CCOP(=O)(Cc1ccc(Cn2c(Br)nc3c(N)nc(OCCOC)nc32)cc1)OCC.C[O-]>>CCOP(=O)(Cc1ccc(Cn2c(OC)nc3c(N)nc(OCCOC)nc32)cc1)OCC -US20100261698A1,2,CC(C)N=C=O.Cn1c(-c2cncc(CN)c2)c(C#N)c2ccc(Cl)cc21>>CC(C)NC(=O)NCc1cncc(-c2c(C#N)c3ccc(Cl)cc3n2C)c1 -US20140296231A1,1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NC[C@H]1C[C@H](O)C1>>NC[C@@H]1C[C@@H](Oc2ccc3ncc(-c4cc5ccccc5o4)n3n2)C1 -US08063234B2,9,CSCc1cccc2c(C(CCOS(C)(=O)=O)(c3ccc(Cl)cc3)C3CC3)c[nH]c12.[C-]#N>>CSCc1cccc2c(C(CCC#N)(c3ccc(Cl)cc3)C3CC3)c[nH]c12 -US07985491B2,3,Brc1ccc2cc(Br)ccc2c1.OB(O)c1cccc(-c2ccccc2)c1>>Brc1ccc2cc(-c3cccc(-c4ccccc4)c3)ccc2c1 -US05401722,2,CC1(C[C@H](O)[C@@H](N)CC2CCCCC2)S(=O)(=O)CCCS1(=O)=O.O=C=Nc1ccccc1>>CC1(C[C@H](O)[C@H](CC2CCCCC2)NC(=O)Nc2ccccc2)S(=O)(=O)CCCS1(=O)=O -US08969349B2,6,CC(=O)N1CCOc2ccc3ccc(CCc4nc5c(C)ncc(C)n5n4)nc3c21>>Cc1ncc(C)n2nc(CCc3ccc4ccc5c(c4n3)NCCO5)nc12 -US07919621B2,1,Clc1cc(Cl)c2ccc(I)cc2n1.N#CC1(c2cccc(S)c2)CCOCC1>>N#CC1(c2cccc(Sc3ccc4c(Cl)cc(Cl)nc4c3)c2)CCOCC1 -US20040006081A1,1,C=CCN.O=C1CCN(CCC(c2ccccc2)c2ccccc2)CC1>>C=CCNC1CCN(CCC(c2ccccc2)c2ccccc2)CC1 -US20070043048A1,3,CC1(C)CC(Nc2nccc(Cl)n2)CC(C)(C)N1.O=C(O)CCc1ccc(B(O)O)cc1>>CC1(C)CC(Nc2nccc(-c3ccc(CCC(=O)O)cc3)n2)CC(C)(C)N1 -US20110053910A1,1,CN(CCO)C(=O)c1ncc(F)cc1F>>CN1CCOc2cc(F)cnc2C1=O -US20040102464A1,1,Cc1ccc(-c2c(Cl)ncnc2NS(=O)(=O)CCc2ccccc2)cc1.OCCO>>Cc1ccc(-c2c(NS(=O)(=O)CCc3ccccc3)ncnc2OCCO)cc1 -US20140066625A1,3,COC(=O)c1cccc(F)c1Br.Ic1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>COC(=O)c1cccc(F)c1-c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US20090275554A1,5,CCCc1cccc(O)c1.COCCl>>CCCc1cccc(OCOC)c1 -US20130172549A1,6,CCOC(=O)Cc1cn2c(C(=O)NCC34CC5CC(CC(C5)C3)C4)cccc2n1>>O=C(O)Cc1cn2c(C(=O)NCC34CC5CC(CC(C5)C3)C4)cccc2n1 -US20030055244A1,6,CC(C)(C)OC(=O)N1CCC2(CCN(Cc3ccccc3)CC2)C1>>CC(C)(C)OC(=O)N1CCC2(CCNCC2)C1 -US09000025B2,1,CCOC(=O)c1cccc(Sc2c(C)[nH]c3cc(Cl)c(F)cc23)c1.CCn1cc(Br)cn1>>CCOC(=O)c1cccc(Sc2c(C)n(-c3cnn(CC)c3)c3cc(Cl)c(F)cc23)c1 -US20140024650A1,6,COc1ccc(-c2cc(C)on2)cc1F>>Cc1cc(-c2ccc(O)c(F)c2)no1 -US07217697B2,1,BrCc1cccc(Br)c1.CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1O>>CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1OCc1cccc(Br)c1 -US05962470,1,COc1ccc2nc(CO)n(C)c2n1.O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1ccc2nc(COc3ccc(CC4SC(=O)N(C(c5ccccc5)(c5ccccc5)c5ccccc5)C4=O)cc3)n(C)c2n1 -US20090306069A1,3,O=C1CSC(=O)N1.O=Cc1ccc2c(c1)N(Cc1ccccc1)C(=O)CO2>>O=C1NC(=O)C(=Cc2ccc3c(c2)N(Cc2ccccc2)C(=O)CO3)S1 -US06906058B2,1,CCCCC1(CC)CN(c2ccccc2)c2cc(O)ccc2S(=O)(=O)C1.CCOC(=O)CBr>>CCCCC1(CC)CN(c2ccccc2)c2cc(OCC(=O)OCC)ccc2S(=O)(=O)C1 -US04097532,1,CC(C)CC(=O)C(S)C(C)C.COC(=O)CCl>>COC(=O)CSC(C(=O)CC(C)C)C(C)C -US20080114016A1,1,CC(C)(C)OC(=O)NCCCBr.Cc1nn(C2CCCCO2)cc1C(=O)Nc1cc2c(cc1I)CCC(=O)C2>>Cc1nn(C2CCCCO2)cc1C(=O)N(CCCNC(=O)OC(C)(C)C)c1cc2c(cc1I)CCC(=O)C2 -US08633186B2,2,COc1cc(N)c(C#N)cc1OC.NS(=O)(=O)Cl>>COc1cc(C#N)c(NS(N)(=O)=O)cc1OC -US20100298557A1,1,CS(=O)(=O)c1n[nH]c2nc(Cl)nc(NC3CC3)c12.Nc1ccc(N2CCOCC2)cc1>>CS(=O)(=O)c1n[nH]c2nc(Nc3ccc(N4CCOCC4)cc3)nc(NC3CC3)c12 -US20150252032A1,1,CCO.N#Cc1cccc(F)c1F>>CCOc1c(F)cccc1C#N -US20070249670A1,2,COC(=O)[C@](C)(NC(=O)c1cc2ccccc2cc1N)C1CCCCC1.O=C=Nc1c(Cl)cc(OC(F)(F)F)cc1Cl>>COC(=O)[C@](C)(NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cc(OC(F)(F)F)cc1Cl)C1CCCCC1 -US20100317656A1,6,CCOC(=O)c1cn2cc(-c3c[nH]nn3)ccc2n1>>O=C(O)c1cn2cc(-c3c[nH]nn3)ccc2n1 -US20140179743A1,7,CCOc1ccc(/C=C2\SC(=O)N(Cc3ccc([N+](=O)[O-])cc3)C2=O)cc1>>CCOc1ccc(/C=C2\SC(=O)N(Cc3ccc(N)cc3)C2=O)cc1 -US20080269214A1,2,CCOC(=O)c1cncc(-c2ccc([NH3+])cc2)c1.Cc1[nH]c(C(=O)Cl)c(Cl)c1Cl>>CCOC(=O)c1cncc(-c2ccc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)cc2)c1 -US06313310B1,3,COc1ccc(C=O)cc1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1ccc(OC)cc1 -US20100256156A1,3,COC(=O)c1cc(Br)oc1C.COc1ccc(B(O)O)cn1>>COC(=O)c1cc(-c2ccc(OC)nc2)oc1C -US20020019527A1,1,CC(C)(C)OC(=O)NCCN(C(=O)CCl)c1cccc(OC(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCN(c2cccc(OC(F)(F)F)c2)C(=O)C1 -US20080032964A1,7,O=C(CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(OCc2ccccc2)cc1)c1ccc(F)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(OCc3ccccc3)cc2)N1c1ccc(F)cc1 -US20150274663A1,6,CC[C@@H]1CC[C@@H](Oc2ccc(C3=CCN(C(=O)OC(C)(C)C)CC3)cc2)CC1>>CC[C@@H]1CC[C@@H](Oc2ccc(C3=CCNCC3)cc2)CC1 -US20060034796A1,7,O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)OCC1c2ccccc2-c2ccccc21>>Nc1ccc(C(=O)OCCNC(=O)OCC2c3ccccc3-c3ccccc32)cc1 -US20050203064A1,6,CC(C)(C)[Si](C)(C)Oc1ccc(C#CCCn2ccnn2)cc1>>Oc1ccc(C#CCCn2ccnn2)cc1 -US09150555B2,2,CCOC(=O)c1csc(-c2ccc(C(F)(F)F)cc2)n1.Cc1cc(N)cnc1C1=CCC(N2CCOCC2)CC1>>Cc1cc(NC(=O)c2csc(-c3ccc(C(F)(F)F)cc3)n2)cnc1C1=CCC(N2CCOCC2)CC1 -US07423159B2,7,CCOC(=O)CCC(=O)NCc1ccc([N+](=O)[O-])cc1>>CCOC(=O)CCC(=O)NCc1ccc(N)cc1 -US20120238588A1,3,CC[Mg+].O=C(O)c1ccc(Br)cc1F>>CCc1cc(Br)ccc1C(=O)O -US20120142752A1,9,CC(C)(C)OC(=O)N[C@@H]1CN(Cc2ccccc2)C[C@H]1N=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@@H]1CN(Cc2ccccc2)C[C@H]1N -US20120035208A1,3,CC1(C)OB(c2ccc3[nH]ncc3c2)OC1(C)C.Cn1ncc2c(Cl)cc(Cl)nc21>>Cn1ncc2c(Cl)cc(-c3ccc4[nH]ncc4c3)nc21 -US20140378487A1,1,COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.N#Cc1cc(CS)ccc1Oc1cccc(C(F)(F)F)c1>>COc1ccc2c(c1)CCn1c-2cc(SCc2ccc(Oc3cccc(C(F)(F)F)c3)c(C#N)c2)nc1=O -US20130261113A1,6,CC(C)(C)OC(=O)N1CCOC(CO)C1>>OCC1CNCCO1 -US20140296515A1,1,N#Cc1c(Cl)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1ccc(OCCO)cc1.NCCF>>N#Cc1c(NCCF)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1ccc(OCCO)cc1 -US20100324030A1,8,O=C1COc2cc(CO)ccc2N1>>O=Cc1ccc2c(c1)OCC(=O)N2 -US20090264336A1,2,CC(C)Oc1cc(OCc2ccccc2)cc(C(=O)O)c1.Cn1ccc(N)n1>>CC(C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2ccn(C)n2)c1 -US08349836B2,1,NCc1cccc(C(F)(F)F)c1Cl.O=c1[nH]nc(Cl)c2cc(Br)ccc12>>O=c1[nH]nc(Cl)c2cc(NCc3cccc(C(F)(F)F)c3Cl)ccc12 -US20060229312A1,7,Cc1ccc2c(N3CCN(CCc4cccc([N+](=O)[O-])c4)CC3)c(F)ccc2n1>>Cc1ccc2c(N3CCN(CCc4cccc(N)c4)CC3)c(F)ccc2n1 -US20060142337A1,9,C[C@@H](O[C@H]1CCN(C(=O)[C@@H]2CC[C@@H](C(=O)O)CC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.N>>C[C@@H](O[C@H]1CCN(C(=O)[C@@H]2CC[C@@H](C(N)=O)CC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US07576100B2,1,CCCCC1CC2CCC(C1)N2.C[C@H](CI)CN1C(=O)COc2ccccc21>>CCCCC1CC2CCC(C1)N2C[C@@H](C)CN1C(=O)COc2ccccc21 -US20120121540A1,6,CC(C)(C)OC(=O)N1CC=C(c2ccccc2F)CC1>>Fc1ccccc1C1=CCNCC1 -US05488055,1,CCn1nccc1N.O=C(O)c1cc([N+](=O)[O-])ccc1Cl>>CCn1nccc1Nc1ccc([N+](=O)[O-])cc1C(=O)O -US04412078,1,CC1(C)NC(=O)NC1=O.CO[Si](CCCCl)(OC)OC>>CO[Si](CCCN1C(=O)NC(=O)C1(C)C)(OC)OC -US05296495,1,CC(C)(C)c1csc(-c2cc3cc(O)ccc3o2)n1.N#Cc1cccc(CBr)c1>>CC(C)(C)c1csc(-c2cc3cc(OCc4cccc(C#N)c4)ccc3o2)n1 -US20040116483A1,2,CC(C)(C)C1CCC(NCc2ccc(C(O)Cc3nn[nH]n3)cc2)CC1.O=C=Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(C)(C)C1CCC(N(Cc2ccc(C(O)Cc3nn[nH]n3)cc2)C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US08026257B2,6,Cn1ncc2cc(-c3ccc(C#N)cc3)cc(COCC3(c4ccccc4)CCN(C(=O)OC(C)(C)C)CC3)c21>>Cn1ncc2cc(-c3ccc(C#N)cc3)cc(COCC3(c4ccccc4)CCNCC3)c21 -US04521430,2,COc1ccc([C@@H]2Sc3ccccc3NC(=O)[C@@H]2O)cc1.O=C(Cl)c1ccc([N+](=O)[O-])cc1Cl>>COc1ccc([C@@H]2Sc3ccccc3NC(=O)[C@@H]2OC(=O)c2ccc([N+](=O)[O-])cc2Cl)cc1 -US20140018326A1,7,COC(=O)[C@H](CS)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@H](CO)CS -US04892873,1,C=CCBr.CC(=O)Nc1cccc(-c2ccc3nnc(C)n3n2)c1>>C=CCN(C(C)=O)c1cccc(-c2ccc3nnc(C)n3n2)c1 -US07138425B2,3,COc1ccc(-c2nc3cc(Br)ccc3o2)cc1[N+](=O)[O-].Cc1cc(B(O)O)ccc1Cl>>COc1ccc(-c2nc3cc(-c4ccc(Cl)c(C)c4)ccc3o2)cc1[N+](=O)[O-] -US06670373B1,6,CCOC(=O)c1c(-c2cc(I)ccc2F)noc1C>>Cc1onc(-c2cc(I)ccc2F)c1C(=O)O -US08354444B2,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1.CC1(C)OCC(Cn2ccc(N)n2)O1>>CC(C)(C)CC1NC(C(=O)Nc2ccn(C[C@@H]3COC(C)(C)O3)n2)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1 -US06017910,3,O=C(Cl)Cc1ccc(Br)cc1.c1ccccc1>>O=C(Cc1ccc(Br)cc1)c1ccccc1 -US20140275528A1,2,CC(C)(Br)C(=O)Br.CCC(N)CO>>CCC(CO)NC(=O)C(C)(C)Br -US04866064,3,C#CC.CCCCCCSc1nn2c(=O)cc(I)nc2s1>>CC#Cc1cc(=O)n2nc(SCCCCCC)sc2n1 -US08927536B2,2,C1CCNCC1.CC1(CO)Cc2nnc(C3(c4ccc(-c5ccc(C(=O)O)cn5)cc4)CC3)n2CCS1>>CC1(CO)Cc2nnc(C3(c4ccc(-c5ccc(C(=O)N6CCCCC6)cn5)cc4)CC3)n2CCS1 -US20050054626A1,1,COC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1NC(=O)CN.FC(F)(F)c1ccc2ncnc(Cl)c2c1>>COC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1NC(=O)CNc1ncnc2ccc(C(F)(F)F)cc12 -US20040138223A1,2,CC(C)c1ccc(NCCCCCCOC2CCCCO2)cc1.O=C(O)C1CCCc2ccccc21>>CC(C)c1ccc(N(CCCCCCOC2CCCCO2)C(=O)C2CCCc3ccccc32)cc1 -US20150051195A1,3,CC(C)c1ccc(B(O)O)cc1.CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1ccc(C(C)C)cc1 -US20050004161A1,1,O=C(NCc1ccc(Cl)cc1)c1cn(CCO)c2sc(CCl)cc2c1=O.OC[C@@H](O)c1ccccc1>>O=C(NCc1ccc(Cl)cc1)c1cn(CCO)c2sc(COC[C@@H](O)c3ccccc3)cc2c1=O -US20090176804A1,7,COC(=O)C(=O)c1c(-c2ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c2)[nH]c2c(Cl)cccc12>>COC(=O)Cc1c(-c2ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c2)[nH]c2c(Cl)cccc12 -US20060287356A1,3,N#Cc1c(O)c2c(-c3ccc(Br)cc3)csc2[nH]c1=O.OB(O)c1ccsc1>>N#Cc1c(O)c2c(-c3ccc(-c4ccsc4)cc3)csc2[nH]c1=O -US06593335B1,10,Cc1ccc(F)c(C#N)c1.O=C1CCC(=O)N1Br>>N#Cc1cc(CBr)ccc1F -US07649001B2,1,CI.N#Cc1ccc(N2CCC(CO)C2)c2ccccc12>>COCC1CCN(c2ccc(C#N)c3ccccc23)C1 -US04931083,2,CC(Oc1ncn(-c2ccc(C(F)(F)F)cc2)n1)C(=O)O.CNC>>CC(Oc1ncn(-c2ccc(C(F)(F)F)cc2)n1)C(=O)N(C)C -US07227023B2,1,CC(=O)OC(CBr)Cc1c(O)ccc2ncccc12>>CC(=O)OC1COc2ccc3ncccc3c2C1 -US20130109696A1,3,COc1cc(C(F)(F)F)ccc1CBr.COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(B3OCC(C)(C)CO3)c(C#N)c2)c(OC)c1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(Cc3ccc(C(F)(F)F)cc3OC)c(C#N)c2)c(OC)c1 -US20110124665A1,1,COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1.Oc1cccc(O)c1>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Oc4cccc(O)c4)c23)cc1 -US08415378B2,3,COC(=O)c1ccnc(Cl)c1.FC1(F)CCC(C[Zn+])CC1>>COC(=O)c1ccnc(CC2CCC(F)(F)CC2)c1 -US06429214B1,2,CC(C)(C)OC(=O)NCCCN.COC(=O)CC1Cc2ccc(C(=O)O)cc2NC1=O>>COC(=O)CC1Cc2ccc(C(=O)NCCCNC(=O)OC(C)(C)C)cc2NC1=O -US20130131039A1,3,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CN1CCC(c2ccc(-c3cc4nccn4c(Cl)n3)cc2)CC1>>CN1CCC(c2ccc(-c3cc4nccn4c(-c4cn[nH]c4)n3)cc2)CC1 -US08809352B2,6,CC(C)(C)OC(=O)N1CCC(=O)C(F)C1>>O=C1CCNCC1F -US20100273832A1,9,Nc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1Br.[C-]#N>>N#Cc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1N -US20100197681A1,2,Nc1nc2cccc(-c3ccoc3)n2n1.O=C(Cl)c1ccc2c(c1)OCCO2>>O=C(Nc1nc2cccc(-c3ccoc3)n2n1)c1ccc2c(c1)OCCO2 -US20120121540A1,3,O=C(NCc1cccs1)c1cc2cc(Br)cc(Cl)c2[nH]1.OB(O)c1ccccc1>>O=C(NCc1cccs1)c1cc2cc(-c3ccccc3)cc(Cl)c2[nH]1 -US20040259910A1,6,CCC(C)Oc1cccc(CC(=O)OC)c1>>CCC(C)Oc1cccc(CC(=O)O)c1 -US06982348B2,6,CCOC(=O)C(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1>>O=C(O)C(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1 -US20120088791A1,1,CCOC(=O)N1CCC(=O)CC1.COc1cccc(C(=O)N[C@@H]2CCCNC2)c1>>CCOC(=O)N1CCC(N2CCC[C@@H](NC(=O)c3cccc(OC)c3)C2)CC1 -US20090227555A2,2,CCOC(=O)c1cc(C#N)c(N2CC(N)C2)nc1C.O=C=NS(=O)(=O)c1ccc(Cl)cc1>>CCOC(=O)c1cc(C#N)c(N2CC(NC(=O)NS(=O)(=O)c3ccc(Cl)cc3)C2)nc1C -US08227623B2,1,BrCc1ccccc1Br.CCOP(OCC)OCC>>CCOP(=O)(Cc1ccccc1Br)OCC -US07001897B2,2,CS(=O)(=O)Cl.O=C(c1csc(N2CC(O)C2)n1)N1CCOCC1>>CS(=O)(=O)OC1CN(c2nc(C(=O)N3CCOCC3)cs2)C1 -US04352931,7,Cc1cc2cn[nH]c2cc1[N+](=O)[O-]>>Cc1cc2cn[nH]c2cc1N -US20040235822A1,7,O=[N+]([O-])c1ccc(C(O)c2ccccn2)c(OCC(F)(F)F)c1>>Nc1ccc(C(O)c2ccccn2)c(OCC(F)(F)F)c1 -US20030191110A1,2,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O.c1ccc(CC2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)N1CCC(Cc2ccccc2)CC1 -US20120270865A2,6,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(OCc4ccccn4)cc3c2C)C2CCCCC2)cc1>>Cc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)cc2)C2CCCCC2)oc2ccc(OCc3ccccn3)cc12 -US20120184515A1,1,CC(O)c1ccc([C@H]2C[C@@]3(C)[C@@H](CC[C@@]3(O)C(F)(F)C(F)(F)F)[C@@H]3CCC4=CC(=O)CCC4=C23)cc1.Cc1nc2cc(CBr)ccc2s1>>Cc1nc2cc(COC(C)c3ccc([C@H]4C[C@@]5(C)[C@@H](CC[C@@]5(O)C(F)(F)C(F)(F)F)[C@@H]5CCC6=CC(=O)CCC6=C45)cc3)ccc2s1 -US20130225552A1,4,CNc1cc(F)cnc1N.O=C(n1ccnc1)n1ccnc1>>Cn1c(=O)[nH]c2ncc(F)cc21 -US20100173968A1,2,CC(C)(C)OC(=O)N1CC2CC(C(=O)O)CC2C1.NCC(F)(F)F>>CC(C)(C)OC(=O)N1CC2CC(C(=O)NCC(F)(F)F)CC2C1 -US08569535B2,2,CCOC(=O)C1(N)Cc2ccccc2C1.Cc1cccc(C(=O)O)c1O>>CCOC(=O)C1(NC(=O)c2cccc(C)c2O)Cc2ccccc2C1 -US20100004249A1,6,Cc1cccc(N2CC3CN(C(=O)OC(C)(C)C)CCN3C2=O)c1>>Cc1cccc(N2CC3CNCCN3C2=O)c1 -US20150210688A1,2,NCc1cc(Br)ccn1.O=CO>>O=CNCc1cc(Br)ccn1 -US20120101093A1,6,CC(C)(C)OC(=O)N1CCC(Oc2cccc3nc(C(=O)Nc4nc5cc(-c6cccc(C(F)(F)F)c6)ccc5[nH]4)cn23)CC1>>O=C(Nc1nc2cc(-c3cccc(C(F)(F)F)c3)ccc2[nH]1)c1cn2c(OC3CCNCC3)cccc2n1 -US08501780B2,3,CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(Br)cc23)CC1.OB(O)c1cccnc1>>CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(-c4cccnc4)cc23)CC1 -US20060173004A1,2,CC(C)(C)OC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)O.C[C@H]1CN(Cc2ccc(F)cc2)[C@H](C)CN1>>C[C@H]1CN(Cc2ccc(F)cc2)[C@H](C)CN1C(=O)/C=C/c1ccc(Cl)cc1NC(=O)OC(C)(C)C -US08133901B2,2,Cc1nc(C(=O)O)c(-c2cccc(F)c2)s1.Cc1nc2sccn2c1C(=O)N[C@@H]1CCCNC1>>Cc1nc(C(=O)N2CCC[C@@H](NC(=O)c3c(C)nc4sccn34)C2)c(-c2cccc(F)c2)s1 -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.N#Cc1ncccc1O>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4cccnc4C#N)ncnc32)CC1 -US04743685,1,BrCc1ccccc1.O=c1cc(CO)occ1O>>O=c1cc(CO)occ1OCc1ccccc1 -US07087756B2,2,CN.Cc1noc(-c2ccccc2)c1C(=O)O>>CNC(=O)c1c(C)noc1-c1ccccc1 -US07572808B2,1,CN.O=c1n(Cc2ccc(C(F)(F)F)nc2Cl)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn12>>CNc1nc(C(F)(F)F)ccc1Cn1nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn2c1=O -US20130150401A1,3,CC(C)(C)OC(=O)N1CCC([C@]2(C)Cc3cc(Cl)ncc3O2)CC1.CC1(C)OB(C2=CCN(S(C)(=O)=O)CC2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC([C@@]2(C)Cc3cc(C4=CCN(S(C)(=O)=O)CC4)ncc3O2)CC1 -US07544704B2,8,Cc1nc(CO)nn1-c1ccc(F)cc1>>Cc1nc(C=O)nn1-c1ccc(F)cc1 -US04994569,2,COc1ccc(C2=NCC(O)C(c3ccccc3)O2)cc1.O=C=Nc1ccccc1>>COc1ccc(C2=NCC(OC(=O)Nc3ccccc3)C(c3ccccc3)O2)cc1 -US06586441B2,10,CSc1nc(N)nc(-c2ccc(C)o2)c1C#N.O=C1CCC(=O)N1Br>>CSc1nc(N)nc(-c2ccc(CBr)o2)c1C#N -US20020028807A1,1,CCN1c2ncc(CCO)cc2C(=O)N(C)c2ccc(F)nc21.Oc1ccnc2ccccc12>>CCN1c2ncc(CCOc3ccnc4ccccc34)cc2C(=O)N(C)c2ccc(F)nc21 -US20130123268A1,6,CC(C)(C)OC(=O)N1C2CCC1CC(O)(c1ncco1)C2>>OC1(c2ncco2)CC2CCC(C1)N2 -US20060074237A1,2,Nc1ccc(COCC2CC2)cn1.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>O=S(=O)(Nc1ccc(COCC2CC2)cn1)c1cccc(C(F)(F)F)c1 -US20140228349A1,3,CC(C)(C)OC(=O)N1CC(=O)C1.C[Mg+]>>CC1(O)CN(C(=O)OC(C)(C)C)C1 -US05124324,2,O=C(O)c1c[nH]c2ccccc12.OCCN1CCCC1>>O=C(OCCN1CCCC1)c1c[nH]c2ccccc12 -US20080262011A1,3,CCCCCCC(C)(C)c1ccc(Br)c(O)c1.OB(O)c1ccncc1>>CCCCCCC(C)(C)c1ccc(-c2ccncc2)c(O)c1 -US06559166B1,1,Fc1ccc(CCBr)c(F)c1.O=S(=O)(c1ccc(Br)cc1)C1CCNCC1>>O=S(=O)(c1ccc(Br)cc1)C1CCN(CCc2ccc(F)cc2F)CC1 -US04987147,9,CC(C)(CCCCOc1ccc(OCCCCCn2ccnc2)cc1)C(N)=O>>CC(C)(C#N)CCCCOc1ccc(OCCCCCn2ccnc2)cc1 -US20060025430A1,2,Nc1ccc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2c1.O=C(Cl)CCl>>O=C(CCl)Nc1ccc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2c1 -US20080145372A1,2,O=C(Cl)Cl.O=[N+]([O-])c1ccc(CO)o1>>O=C(Cl)OCc1ccc([N+](=O)[O-])o1 -US08119627B2,2,CC(C)C(=O)Cl.O=C(NC1CCNCC1)c1ccccc1Oc1ccc(Cl)cc1Cl>>CC(C)C(=O)N1CCC(NC(=O)c2ccccc2Oc2ccc(Cl)cc2Cl)CC1 -US20090054467A1,4,C#CCn1ccnc1.CC(C)(C)CNc1nc(C#N)ncc1Br>>CC(C)(C)Cn1c(Cn2ccnc2)cc2cnc(C#N)nc21 -US20030216476A1,2,COC(=O)c1ccc(S(F)(F)(F)(F)F)cc1Oc1ccc(F)cc1.N=C(N)N>>N=C(N)NC(=O)c1ccc(S(F)(F)(F)(F)F)cc1Oc1ccc(F)cc1 -US20150057240A1,1,BrCc1ccccc1.Cc1ccc(S(=O)(=O)OC2CCC(O)CC2)cc1>>Cc1ccc(S(=O)(=O)OC2CCC(OCc3ccccc3)CC2)cc1 -US20140336383A1,6,CCOC(=O)CNC(=O)c1c(O)n(C2CCCN(C(=O)OCc3ccccc3)C2)c(=O)n(C2CCCCC2)c1=O>>O=C(O)CNC(=O)c1c(O)n(C2CCCN(C(=O)OCc3ccccc3)C2)c(=O)n(C2CCCCC2)c1=O -US05328912,2,O=C(Cl)OCc1ccccc1.O=c1[nH]c2c(c3nc(-c4ccccc4F)cn13)CNCC2>>O=C(OCc1ccccc1)N1CCc2[nH]c(=O)n3cc(-c4ccccc4F)nc3c2C1 -US08362236B2,1,CC(C)(C)OC(=O)NCCCBr.COC(=O)c1cc(-c2cc(Sc3cccc(O)c3)nc(N)n2)c(C)cc1OC>>COC(=O)c1cc(-c2cc(Sc3cccc(OCCCNC(=O)OC(C)(C)C)c3)nc(N)n2)c(C)cc1OC -US07847100B2,1,CN(c1cc(CBr)cc(-c2nnc([C@@](C)(Cc3ccccc3)NC(=O)OC(C)(C)C)o2)c1)S(C)(=O)=O.OC1CCC1>>CN(c1cc(COC2CCC2)cc(-c2nnc([C@@](C)(Cc3ccccc3)NC(=O)OC(C)(C)C)o2)c1)S(C)(=O)=O -US20130274469A1,2,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.N#CC1(N)CC1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2(C#N)CC2)cn1 -US20150284337A1,3,CC(C)Nc1c(C(N)=O)nnc2cc(I)ccc12.CS(=O)(=O)c1ccc(B(O)O)cc1>>CC(C)Nc1c(C(N)=O)nnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 -US20110152245A1,6,CC(C)(C)OC(=O)N1CC(O)C(c2ccc(NC(=O)c3ccc(Cl)cc3)cc2)C1>>O=C(Nc1ccc(C2CNCC2O)cc1)c1ccc(Cl)cc1 -US20110092553A1,1,COC(=O)c1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(-c3ccc(O)cc3)cc2)cc1.O=[N+]([O-])c1ccc(F)cc1>>COC(=O)c1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(-c3ccc(Oc4ccc([N+](=O)[O-])cc4)cc3)cc2)cc1 -US20060217424A1,1,COc1cc(O)ccc1C=O.N#Cc1ccc(Cl)cc1F>>COc1cc(Oc2cc(Cl)ccc2C#N)ccc1C=O -US20120184531A1,1,CC(C)(C)OC(=O)N1CCc2oc3ccc(Br)cc3c2C1.O=S([O-])c1ccc2ccccc2c1>>CC(C)(C)OC(=O)N1CCc2oc3ccc(S(=O)(=O)c4ccc5ccccc5c4)cc3c2C1 -US20150203511A1,7,Cc1c(C(=O)O)cccc1[N+](=O)[O-]>>Cc1c(CO)cccc1[N+](=O)[O-] -US08063046B2,2,COc1ccc(C(N)=O)cc1C(=O)O.Nc1ccc(Br)cc1>>COc1ccc(C(N)=O)cc1C(=O)Nc1ccc(Br)cc1 -US20060189626A1,2,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CNc1cnc(Cl)cc1-c1cccnc1C>>Cc1ncccc1-c1cc(Cl)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20130216552A1,6,CCOC(=O)Cn1c(C)c(Cc2ccccc2S(=O)(=O)N2CCCC2)c2ccsc21>>Cc1c(Cc2ccccc2S(=O)(=O)N2CCCC2)c2ccsc2n1CC(=O)O -US07749530B2,1,CC(=O)c1ccc(C(=O)Nc2ccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)cc2)s1.Nc1cccc(O)c1>>CC(=O)c1ccc(C(=O)Nc2ccc(C(=O)c3ccc4c(c3)NC(=O)C4=CNc3cccc(O)c3)cc2)s1 -US20100197711A1,9,Clc1nc2ccccc2s1.NN>>NNc1nc2ccccc2s1 -US20110190227A1,2,CCOC(=O)Cc1ccc(OC)c(Oc2ccc(N)cc2CSC(C)(C)C)c1.O=C(Cl)c1ccc(Cl)cc1Cl>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2CSC(C)(C)C)c1 -US06252086B1,3,C#CCN1CCCCC1.Cc1nc[nH]c1/C=C1\C(=O)Nc2ccc(F)c(I)c21>>Cc1nc[nH]c1/C=C1\C(=O)Nc2ccc(F)c(C#CCN3CCCCC3)c21 -US09156829B2,2,N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1.O=C(O)c1cc(Cl)ccc1-n1ccnn1>>O=C(N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1)c1cc(Cl)ccc1-n1ccnn1 -US20150025054A1,1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.N[C@@H]1C[C@H]1c1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CCC(CN[C@@H]2C[C@H]2c2ccc(Br)cc2)CC1 -US05698720,2,COc1ccc(C(C)(C)N)cc1.C[C@]12CC[C@H]3[C@@H](CC=C4C=C(C#N)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)O>>COc1ccc(C(C)(C)NC(=O)[C@H]2CC[C@H]3[C@@H]4CC=C5C=C(C#N)CC[C@]5(C)[C@H]4CC[C@]23C)cc1 -US05972975,2,CC(=O)OC(C)=O.Cc1cc(N)ncc1CN>>CC(=O)NCc1cnc(N)cc1C -US06303789B1,1,COc1ccc(C#N)cc1OC1COCC1O.ClCc1ccccc1>>COc1ccc(C#N)cc1OC1COCC1OCc1ccccc1 -US04922021,1,CC(Br)CCBr.Cc1cccc(C)c1NS(C)(=O)=O>>Cc1cccc(C)c1N(CCC(C)Br)S(C)(=O)=O -US08501765B2,1,CCI.N#Cc1ncc2c(c1O)c1cc(Br)cnc1n2S(=O)(=O)c1ccccc1>>CCOc1c(C#N)ncc2c1c1cc(Br)cnc1n2S(=O)(=O)c1ccccc1 -US20080182814A1,9,O=C(OC[C@@H]1O[C@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@H]1OC(=O)c1ccccc1)c1ccccc1>>O=C(OC[C@@H]1O[C@H](n2ccc(=O)[nH]c2=O)C[C@H]1OC(=O)c1ccccc1)c1ccccc1 -US20080200448A1,9,CCOC(=O)c1cc(Br)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1CN1CCCC1=O>>CCOC(=O)c1ccc(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1CN1CCCC1=O -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.O=C1OC[C@H](c2ccc(F)c(F)c2)N1CCCCCCl>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCCN3C(=O)OC[C@@H]3c3ccc(F)c(F)c3)CC2)c1 -US20100160424A1,7,COC(=O)c1cccc(C(OCC#N)c2ccccc2)c1>>COC(=O)c1cccc(C(OCCN)c2ccccc2)c1 -US20150196540A1,1,CCI.O=Cc1ccc(C(=O)O)cc1>>CCOC(=O)c1ccc(C=O)cc1 -US04119106,1,C=C(C)[O-].CC(C)=CCCC(C)CCOC(=O)Cl>>C=C(C)OC(=O)OCCC(C)CCC=C(C)C -US06878750B2,6,ClCCCCCCOc1ccc(C2=C(c3ccccc3)CCCc3cc(OC4CCCCO4)ccc32)cc1>>Oc1ccc2c(c1)CCCC(c1ccccc1)=C2c1ccc(OCCCCCCCl)cc1 -US20040162303A1,3,CCSc1ncc(C(=O)N(C)OC)c(N)n1.COc1ccc(OC)c(Br)c1>>CCSc1ncc(C(=O)c2cc(OC)ccc2OC)c(N)n1 -US06313162B1,3,CC1(C)CCC(C)(C)c2cc(C(=O)Cl)ccc21.COC(=O)c1ccc(C#C[Si](C)(C)C)cc1>>COC(=O)c1ccc(C#CC(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 -US06136823,1,CN.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(F)c32)c(F)cc1F>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3nc(N)c(F)cc3F)c2c1F -US06440970B1,1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2.COc1ccc(Oc2cncc(Br)c2)cc1>>COc1ccc(Oc2cncc(N3C[C@@H]4C[C@H]3CN4C(=O)OC(C)(C)C)c2)cc1 -US04704161,3,C#CCCC(C)C.CCCCOC(=O)C=O>>CCCCOC(=O)C(O)C#CCCC(C)C -US05273999,1,COC(=O)/C=C/c1c(O)cccc1C#CCCCCO.COC(=O)CCCCCCCCBr>>COC(=O)/C=C/c1c(C#CCCCCO)cccc1OCCCCCCCCC(=O)OC -US09040538B2,7,CCn1cnc(C=O)c1C>>CCn1cnc(CO)c1C -US04994569,2,COc1ccc(C2=NC(c3ccccc3)C(O)CO2)cc1.O=C=Nc1ccc(Cl)c(Cl)c1>>COc1ccc(C2=NC(c3ccccc3)C(OC(=O)Nc3ccc(Cl)c(Cl)c3)CO2)cc1 -US07223757B2,1,Cc1cc(Br)cc2[nH]c(-c3c(Cl)cc[nH]c3=O)nc12.N[C@H](CO)Cc1ccccc1>>Cc1cc(Br)cc2[nH]c(-c3c(N[C@H](CO)Cc4ccccc4)cc[nH]c3=O)nc12 -US07332497B2,1,BrCc1ccc(Br)cc1.c1ccc2[nH]cnc2c1>>Brc1ccc(Cn2cnc3ccccc32)cc1 -US20070287699A1,1,CC(C)(C)c1ccc(CCl)cc1.N#Cc1c[nH]c2cc(F)c(F)cc2c1=O>>CC(C)(C)c1ccc(Cn2cc(C#N)c(=O)c3cc(F)c(F)cc32)cc1 -US08044069B2,2,Fc1ccc(C(=C2CCNCC2)c2ccc(F)cc2)cc1.O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCCC(c2ccccc2)(c2ccccc2)C1=O)N1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US09138013B2,7,CC(C)(C)OC(=O)N1CCC[C@H](COc2cccc([N+](=O)[O-])c2C#N)C1>>CC(C)(C)OC(=O)N1CCC[C@H](COc2cccc(N)c2C#N)C1 -US20100216810A1,7,COC(=O)c1c(Oc2cccc(NC(=O)c3cccc(C(C)(C)C#N)c3)c2)ccc2nc(NC(=O)C3CC3)sc12>>CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3CO)c2)c1 -US04486444,1,COc1ccc(C(=O)c2ccc(Br)s2)cc1.SCc1ccccc1>>COc1ccc(C(=O)c2ccc(SCc3ccccc3)s2)cc1 -US06479463B1,8,NSc1nc(N)nc2c1ncn2[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O.O=C(OO)c1cccc(Cl)c1>>Nc1nc(S(N)=O)c2ncn([C@H]3O[C@@H](CO)[C@H](O)[C@@H]3O)c2n1 -US20090286778A1,1,NC1CCN(C(=O)OCc2ccccc2)CC1.O=[N+]([O-])c1ccc(F)c(I)c1>>O=C(OCc1ccccc1)N1CCC(Nc2ccc([N+](=O)[O-])cc2I)CC1 -US20070161681A1,4,CC(C#N)Oc1ccc(CNC(=O)c2cccnc2Oc2ccc3c(c2)OCO3)c(F)c1.C[Si](C)(C)N=[N+]=[N-]>>CC(Oc1ccc(CNC(=O)c2cccnc2Oc2ccc3c(c2)OCO3)c(F)c1)c1nnn[nH]1 -US20140187553A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1nc(Br)ns1>>CC(C)(C)OC(=O)Nc1nc(Br)ns1 -US06921763B2,3,Nc1ncnc2c1c(I)nn2-c1cc[n+]([O-])cc1.OB(O)c1ccc(Oc2ccccc2)cc1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2-c1cc[n+]([O-])cc1 -US20100305133A1,6,CCOC(=O)CNC(=O)c1c(O)c(-c2ccc(F)c(F)c2)cc2nc(-c3ccc(F)c(F)c3)cnc12>>O=C(O)CNC(=O)c1c(O)c(-c2ccc(F)c(F)c2)cc2nc(-c3ccc(F)c(F)c3)cnc12 -US20110076291A1,2,CN.Nc1nc(-c2cc3c(s2)-c2ccc(C(=O)O)cc2OCC3)n(-c2ccc(F)cc2F)n1>>CNC(=O)c1ccc2c(c1)OCCc1cc(-c3nc(N)nn3-c3ccc(F)cc3F)sc1-2 -US20090143353A1,9,CCOC(=O)C(C)(C)c1nc2c(C#N)c(C)c(-c3ccccc3)c(F)c2o1.[NH4+]>>Cc1c(-c2ccccc2)c(F)c2oc(C(C)(C)C(N)=O)nc2c1C#N -US07491819B1,1,N#Cc1ccc(F)cc1Br.O=C1NCCO1>>N#Cc1ccc(F)cc1N1CCOC1=O -US05550254,6,COc1ccc2c(c1)[C@]1(C)CCN(CCc3ccccc3)[C@@H]1N2C>>CN1c2ccc(O)cc2[C@]2(C)CCN(CCc3ccccc3)[C@H]12 -US20070054916A1,3,Cc1ccccc1B(O)O.Nc1ncc2cc(Cl)cnc2n1>>Cc1ccccc1-c1cnc2nc(N)ncc2c1 -US20140142114A1,2,FC(F)(F)c1ccc2c(c1)CC(CN1CCNCC1)O2.O=C(O)COC1CCC(Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1>>O=C(COC1CCC(Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1)N1CCN(CC2Cc3cc(C(F)(F)F)ccc3O2)CC1 -US06166006,1,Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CCl)cc3)c2)cc1.OCC1CCCNC1>>Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CN4CCCC(CO)C4)cc3)c2)cc1 -US20030078254A1,1,CN.O=Cc1cccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)c1>>CNCc1cccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)c1 -US20100249123A1,2,COc1ccc(C(=O)Nc2cccc(C(C)(C)CN)c2)cc1OC.O=C(O)c1cnc2ccccn12>>COc1ccc(C(=O)Nc2cccc(C(C)(C)CNC(=O)c3cnc4ccccn34)c2)cc1OC -US20090030015A1,7,COC(=O)Cc1ccc(-c2cccc([N+](=O)[O-])c2)s1>>COC(=O)Cc1ccc(-c2cccc(N)c2)s1 -US20150065464A1,1,CNC.O=C(NC1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1)c1ccc(Cl)nc1>>CN(C)c1ccc(C(=O)NC2CCC(=Cc3cccc(Oc4ccc(C(F)(F)F)cn4)c3)CC2)cn1 -US20110021352A1,7,CCOC(=O)c1cc2ccc(C(C)=O)nc2nc1C(F)(F)F>>CCOC(=O)c1cc2ccc(C(C)O)nc2nc1C(F)(F)F -US20070232610A1,6,COCC1(C(=O)OC)CCN(CC(=O)OC(C)(C)C)C1>>COCC1(C(=O)OC)CCN(CC(=O)O)C1 -US20090029991A1,3,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(C2=CCN(C(=O)OC(C)(C)C)CC2)cc1 -US20100130737A1,6,CCOC(=O)C1(NC(=O)Cc2ccc(OCc3ccsc3)cc2)Cc2ccc(-c3ccc(Cl)cc3)cc2C1>>O=C(Cc1ccc(OCc2ccsc2)cc1)NC1(C(=O)O)Cc2ccc(-c3ccc(Cl)cc3)cc2C1 -US20090247526A1,6,COc1ccc(Oc2ccnc(Nc3nc(C)cs3)c2)cc1>>Cc1csc(Nc2cc(Oc3ccc(O)cc3)ccn2)n1 -US08642768B2,7,COC(=O)c1cc(C)c([N+](=O)[O-])c(C)c1>>COC(=O)c1cc(C)c(N)c(C)c1 -US20090247517A1,1,CNC.Clc1ccc(-c2nc3c(cnn3-c3ccccc3)c(Cl)c2-c2ccc(Cl)cc2)cc1>>CN(C)c1c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc2c1cnn2-c1ccccc1 -US08629430B2,3,COc1cccc(B(O)O)c1OC.Fc1ccccc1Br>>COc1cccc(-c2ccccc2F)c1OC -US08003649B2,1,FC(F)(F)c1ccc(C(c2ccccc2)N2CCNCC2)cc1.FC(F)(F)c1nnc2ccc(Cl)nn12>>FC(F)(F)c1ccc(C(c2ccccc2)N2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US08940771B2,9,COC(=O)[C@@H]1C[C@H](O)CN1.N>>NC(=O)[C@@H]1C[C@H](O)CN1 -US20150111866A1,3,COC(=O)c1cc(C)c(B2OC(C)(C)C(C)(C)O2)c(C)c1.COc1ccc(Br)cn1>>COC(=O)c1cc(C)c(-c2ccc(OC)nc2)c(C)c1 -US20090176841A1,2,CC(C)c1cc(C(=O)Cl)ccc1OCc1ccccc1.Cc1ccc([N+](=O)[O-])c2cc[nH]c12>>Cc1ccc([N+](=O)[O-])c2ccn(C(=O)c3ccc(OCc4ccccc4)c(C(C)C)c3)c12 -US07902201B2,2,COC(=O)c1cnc(NCc2c(-c3ccccc3)noc2C)cn1.NC1CCOCC1>>Cc1onc(-c2ccccc2)c1CNc1cnc(C(=O)NC2CCOCC2)cn1 -US04464300,7,CC(=O)Nc1ccc(N)c(C(=O)c2ccccc2Cl)c1>>CC(=O)Nc1ccc(N)c(C(O)c2ccccc2Cl)c1 -US04588723,3,CCN(CC)Cc1nn2cc(-c3ccccc3)nc2s1.CN(C)C=O>>CCN(CC)Cc1nn2c(C=O)c(-c3ccccc3)nc2s1 -US08067511B2,3,COc1c(Br)cccc1C(C)C.OB(O)c1ccccc1>>COc1c(-c2ccccc2)cccc1C(C)C -US20080194629A1,2,COCCOCC1(CNC(=O)[C@H]2C[C@@H](N)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)c2ccccc2Oc2ccccc21.O=S(=O)(Cl)c1ccc(F)cc1>>COCCOCC1(CNC(=O)[C@H]2C[C@@H](NS(=O)(=O)c3ccc(F)cc3)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)c2ccccc2Oc2ccccc21 -US20110275630A1,4,COc1ccc(C(=O)CBr)cc1.NC(=S)Nc1ccc(-c2cccc3c2CNC3=O)cc1>>COc1ccc(-c2csc(Nc3ccc(-c4cccc5c4CNC5=O)cc3)n2)cc1 -US20150038488A1,3,C[C@@H](Oc1nc(Cl)cc2ncn(C)c12)[C@H]1CNC(=O)C1.Cn1ncc2cc(B(O)O)ccc21>>C[C@@H](Oc1nc(-c2ccc3c(cnn3C)c2)cc2ncn(C)c12)[C@H]1CNC(=O)C1 -US20070072897A1,2,Cc1ccc(C(=O)O)cc1Cl.Nc1ccc2[nH]ccc2c1>>Cc1ccc(C(=O)Nc2ccc3[nH]ccc3c2)cc1Cl -US07727997B2,1,CCCCN.COC(=O)c1cc(C)cc(CO)c1>>CCCCNCc1cc(C)cc(C(=O)OC)c1 -US20020032184A1,6,Cc1c(Cc2cc(Cl)cc(Cl)c2)c(NC(=O)OC(C)(C)C)nn1CCO>>Cc1c(Cc2cc(Cl)cc(Cl)c2)c(N)nn1CCO -US20150252044A1,3,CC(NC(=O)c1ccc2cncc(Br)c2n1)C(C)(C)O.OB(O)c1cccc(OCC(F)(F)F)c1>>CC(NC(=O)c1ccc2cncc(-c3cccc(OCC(F)(F)F)c3)c2n1)C(C)(C)O -US20090018122A1,1,COCCc1nc2c(N)nc3cc(O)ccc3c2n1CC(C)(C)O.OCc1cccnc1>>COCCc1nc2c(N)nc3cc(OCc4cccnc4)ccc3c2n1CC(C)(C)O -US20090312342A1,1,CC(C)C[C@@H](O)C(=O)N1CCNCC1.Cc1ccc2c(Cl)nc(-c3c(O)cccc3F)nc2c1>>Cc1ccc2c(N3CCN(C(=O)[C@H](O)CC(C)C)CC3)nc(-c3c(O)cccc3F)nc2c1 -US20150252038A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](O)C1.CC(C)(C)OC(=O)c1cc(Cl)c(F)cc1F>>CC(C)(C)OC(=O)c1cc(Cl)c(O[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)cc1F -US20120095216A1,1,CC1CCOCCN1.Cn1c(Cl)nc(-c2ccncn2)cc1=O>>CC1CCOCCN1c1nc(-c2ccncn2)cc(=O)n1C -US04220795,7,O=C(O)CCC1CCCCC1>>OCCCC1CCCCC1 -US08389527B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(CN(c2cc(N[C@@H]3CC[C@@H](N)CC3)nn3c(C(=O)Nc4ccncc4F)cnc23)C2CC2)cc1>>COc1ccc(CN(c2cc(N[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)nn3c(C(=O)Nc4ccncc4F)cnc23)C2CC2)cc1 -US20110053931A1,6,CCOC(=O)C1CCN(c2ccc(Oc3ccnc4cc(OC)c(OC)cc34)c(F)c2)C1=O>>COc1cc2nccc(Oc3ccc(N4CCC(C(=O)O)C4=O)cc3F)c2cc1OC -US06375922B1,8,OC(c1ccccc1)c1ccccc1>>O=C(c1ccccc1)c1ccccc1 -US06664271B1,2,CCOC(=O)C1CCC(C)NC1.O=C(Cl)Cc1cccs1>>CCOC(=O)C1CCC(C)N(C(=O)Cc2cccs2)C1 -US07691874B2,2,CC(C)(C)OC(=O)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc13.O=C=Nc1ccccc1>>CC(C)(C)OC(=O)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(OC(=O)Nc2ccccc2)cc13 -US08507487B2,6,c1cc2cc(Cn3nnc4ncc(-c5cnn(CCOC6CCCCO6)c5)nc43)ccn2n1>>OCCn1cc(-c2cnc3nnn(Cc4ccn5nccc5c4)c3n2)cn1 -US07273877B2,7,C#Cc1ccc(Nc2cc(=O)n(C)cc2C(N)=O)c(F)c1>>CCc1ccc(Nc2cc(=O)n(C)cc2C(N)=O)c(F)c1 -US20110201608A1,1,Clc1nc(-c2ccc(N3CCOCC3)cc2)cc2ncccc12.Nc1ccc2cn[nH]c2c1>>c1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(Nc3ccc4cn[nH]c4c3)c2c1 -US06489321B1,2,Cc1ccccc1C(=O)Cl.Nc1ccc(S(=O)(=O)N2C=CC(CCO)Sc3ccccc32)cc1>>Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)N2C=CC(CCO)Sc3ccccc32)cc1 -US04369139,2,COc1ccc(C(=O)Cl)cc1.O=C1CCCN1>>COc1ccc(C(=O)N2CCCC2=O)cc1 -US20130338147A1,2,COCCCN.O=[N+]([O-])c1cccc(CS(=O)(=O)Cl)c1>>COCCCNS(=O)(=O)Cc1cccc([N+](=O)[O-])c1 -US20130274469A1,2,C1CSCCN1.Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccncc2)c1COc1ccc(C(=O)N2CCSCC2)cn1 -US20120252782A1,7,CC(C)=CCn1c(N2CCCC(NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(CC(=O)c1ccccc1)c(=O)n2C>>CC(C)=CCn1c(N2CCCC(NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(CC(O)c1ccccc1)c(=O)n2C -US20040132742A1,2,CNc1ccc(OC)c(N2CCN(C)CC2)c1.O=C(O)c1ccc(-c2ccccc2)cc1>>COc1ccc(N(C)C(=O)c2ccc(-c3ccccc3)cc2)cc1N1CCN(C)CC1 -US08575154B2,3,Nc1ncccc1Br.OB(O)c1ccc(F)nc1>>Nc1ncccc1-c1ccc(F)nc1 -US20050014767A1,6,CC(C)(C)[Si](C)(C)Oc1ccc(-c2ccc(C=O)cn2)cc1C1CCCCC1>>O=Cc1ccc(-c2ccc(O)c(C3CCCCC3)c2)nc1 -US04417917,2,O=[N+]([O-])c1ccccc1S(=O)(=O)Cl.OCC(F)(F)F>>O=[N+]([O-])c1ccccc1S(=O)(=O)OCC(F)(F)F -US20100016337A1,6,CC(C)(C)OC(=O)COc1nc(-c2ccc(F)cc2)cs1>>O=C(O)COc1nc(-c2ccc(F)cc2)cs1 -US20100022515A1,1,CCOC(=O)c1cn2c(n1)CNCC2.CCc1cnc(Cl)nc1>>CCOC(=O)c1cn2c(n1)CN(c1ncc(CC)cn1)CC2 -US04428949,7,CC(CF)(CF)C(=O)C(Oc1cccc(C(F)(F)F)c1)n1ccnc1>>CC(CF)(CF)C(O)C(Oc1cccc(C(F)(F)F)c1)n1ccnc1 -US20070238737A1,3,CC1(C)OB(c2ccoc2)OC1(C)C.COc1ccc(N2C[C@H](C)N(C(=O)OC(C)(C)C)[C@H](C)C2)nc1NS(=O)(=O)c1ccc(Br)cc1Cl>>COc1ccc(N2C[C@H](C)N(C(=O)OC(C)(C)C)[C@H](C)C2)nc1NS(=O)(=O)c1ccc(-c2ccoc2)cc1Cl -US20050288273A1,3,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCCC3=O)C(=O)O1.CN(C)CCCOc1ccc(C=O)cc1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(=Cc2ccc(OCCCN(C)C)cc2)C3=O)C(=O)O1 -US20110124636A1,6,COC(=O)c1cccc2ncsc12>>O=C(O)c1cccc2ncsc12 -US20130096144A1,3,Cn1nccc1B1OC(C)(C)C(C)(C)O1.O=C1c2ccccc2C(=O)N1C[C@H](CC1CCCCC1)N1Cc2cc(Br)ccc2C1=O>>Cn1nccc1-c1ccc2c(c1)CN([C@@H](CC1CCCCC1)CN1C(=O)c3ccccc3C1=O)C2=O -US07732618B2,1,CCCc1nc2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C.FC(F)(F)c1ccccc1CBr>>CCCc1nc2cc(N(Cc3ccccc3C(F)(F)F)S(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C -US07749530B2,1,COc1ccc(N)cc1O.Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)c2)n(C)n1>>COc1ccc(NC=C2C(=O)Nc3cc(C(=O)c4cccc(NC(=O)c5cc(C)nn5C)c4)ccc32)cc1O -US20140350015A1,3,COc1ccc(B(O)O)cc1.NC(=O)C1CCN(c2ncncc2Br)CC1>>COc1ccc(-c2cncnc2N2CCC(C(N)=O)CC2)cc1 -US05635510,2,O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.OCCC1(c2ccc(Cl)c(Cl)c2)CCNC1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC(CCO)(c2ccc(Cl)c(Cl)c2)C1 -US20120225857A1,3,CC(C)(C#N)c1ccc(B(O)O)cc1.Nc1ncc(Br)nc1-c1ccc2c(c1)CCNC2=O>>CC(C)(C#N)c1ccc(-c2cnc(N)c(-c3ccc4c(c3)CCNC4=O)n2)cc1 -US04355160,6,CCON=C(C(=O)OCC)c1csc(NC(=O)CCl)n1>>CCON=C(C(=O)O)c1csc(NC(=O)CCl)n1 -US07838087B2,7,CCCC1CCC(C2CCC(C=Cc3ccc(OCC)c(F)c3C(F)(F)F)CC2)CC1>>CCCC1CCC(C2CCC(CCc3ccc(OCC)c(F)c3C(F)(F)F)CC2)CC1 -US20130040930A1,6,CC(=O)N1CCN(c2ccc(C(=O)N3CCN(c4ncc(C5CC5)cc4C)CC3)nn2)C1=O>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CCNC3=O)nn2)CC1 -US20150065480A1,1,CCOC(=O)c1ccccc1F.CCOCCN>>CCOCCNc1ccccc1C(=O)OCC -US20040122026A1,1,Brc1ccc(-c2nnn[nH]2)cc1.Clc1ccccc1C(Cl)(c1ccccc1)c1ccccc1>>Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1nnnc1-c1ccc(Br)cc1 -US20110288291A1,1,CCCN(C)c1cnc(C=O)c(Cl)n1.OCCNCc1ccccc1>>CCCN(C)c1cnc(CN(CCO)Cc2ccccc2)c(Cl)n1 -US05783574,1,Cc1c(CCl)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1NCC2COc3ccccc3N12>>Cc1c(CN2CC3COc4ccccc4N3C2=O)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20090264428A1,6,COC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1>>CN(Cc1ccc(C(=O)O)cc1)C(=O)OC(C)(C)C -US06297257B1,1,BrC1CCCC1.COc1cc(C=O)ccc1O>>COc1cc(C=O)ccc1OC1CCCC1 -US04515811,1,NC1CCCCC1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC1CCCCC1 -US20070123504A1,1,NCC(F)(F)F.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(NCC(F)(F)F)nc1 -US20110263571A1,2,C[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1.Cc1ccc(C(=O)C2CCNCC2)cc1>>Cc1ccc(C(=O)C2CCN(C(=O)c3ccc(N4C(=O)OC[C@H]4C)cc3)CC2)cc1 -US20050032787A1,6,COC(=O)c1cc(C=O)ccc1OC>>COc1ccc(C=O)cc1C(=O)O -US20020147334A1,6,CCOC(=O)CC(Cc1ccc(C(=O)NCCNc2ccccn2)cc1)c1ccccc1>>O=C(O)CC(Cc1ccc(C(=O)NCCNc2ccccn2)cc1)c1ccccc1 -US20070161654A1,2,Cc1onc(-c2ccccc2)c1-c1cn(-c2ccccc2C(=O)O)cn1.NC1CCC1>>Cc1onc(-c2ccccc2)c1-c1cn(-c2ccccc2C(=O)NC2CCC2)cn1 -US06713647B2,3,C#Cc1ccc(CO)c(C)c1.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(C#Cc2ccc(CO)c(C)c2)cc1 -US04461896,6,COc1ccc2nc(C(=O)O)ccc2c1>>O=C(O)c1ccc2cc(O)ccc2n1 -US20120301552A1,3,C=C(C)CCl.Fc1cc(Br)ccc1Cl>>C=C(C)Cc1ccc(Cl)c(F)c1 -US20130089512A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1c(Cl)nc(Cl)nc1NC1CCOCC1>>CC(C)(C)OC(=O)N1CCN(c2nc(Cl)nc(NC3CCOCC3)c2[N+](=O)[O-])CC1 -US06712893B1,1,Cc1ccc(O)cc1.OCCCl>>Cc1ccc(OCCO)cc1 -US20150225405A1,2,Cc1nc(N2CC[C@H](C(=O)O)C2)ncc1-n1c2ccc(F)cc2c2c1cnn2C1CCCCO1.OC1CNC1>>Cc1nc(N2CC[C@H](C(=O)N3CC(O)C3)C2)ncc1-n1c2ccc(F)cc2c2c1cnn2C1CCCCO1 -US07132547B2,2,CN.O=C(CCCCCl)c1cc2c(c(S(=O)(=O)Cl)c1)OCC2>>CNS(=O)(=O)c1cc(C(=O)CCCCCl)cc2c1OCC2 -US04105773,2,C=CC(=O)Cl.Nc1csc(Br)n1>>C=CC(=O)Nc1csc(Br)n1 -US20150023990A1,1,CC(C)(C)OC(=O)NCCCCCCI.CCCn1c(COCC)nc2cnc3ccc(O)cc3c21>>CCCn1c(COCC)nc2cnc3ccc(OCCCCCCNC(=O)OC(C)(C)C)cc3c21 -US07932390B2,2,CCOC(=O)c1cnc(N)c2c(COc3cccc(-c4nnc(C)o4)c3)csc12.NCCO>>Cc1nnc(-c2cccc(OCc3csc4c(C(=O)NCCO)cnc(N)c34)c2)o1 -US20130096317A1,6,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)CCl>>[NH3+][C@@H](Cc1ccccc1)C(=O)CCl -US20150087663A1,1,CC[C@H](N)c1nc2cccc(C)c2c(=O)n1-c1ccccc1C.Cn1cnc(-c2c(N)ncnc2Cl)n1>>CC[C@H](Nc1ncnc(N)c1-c1ncn(C)n1)c1nc2cccc(C)c2c(=O)n1-c1ccccc1C -US20140066455A1,2,COC(=O)c1cnc(N2CCN(C3CC3)CC2)nc1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3cnc(N4CCN(C5CC5)CC4)nc3)[nH]n2)cc(OC)c1 -US03987160,7,Nc1nc(-c2cccc(Cc3ccccc3)c2)[nH]c(=O)c1N=O>>Nc1nc(-c2cccc(Cc3ccccc3)c2)[nH]c(=O)c1N -US06756374B2,7,CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2)CC1 -US04093742,2,CCN=C=O.Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2c1CCC2>>CCNC(=O)Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2c1CCC2 -US09102591B2,2,Cc1ncc(C2(CN)CCOCC2)cn1.O=C(O)c1ccccc1Cl>>Cc1ncc(C2(CNC(=O)c3ccccc3Cl)CCOCC2)cn1 -US20100249179A1,6,CCOC(=O)c1cc(=O)oc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)ccc12>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3c(C(=O)O)cc(=O)oc3c2)cc1 -US06239151B1,5,CC(C)CNNC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)C(F)(F)F)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C -US07109186B2,1,CC1(C)OC(=O)C(=CC(=O)Cl)O1.Fc1ccc(CNOCCCN2CCOCC2)cc1>>CC1(C)OC(=O)C(=CC(=O)N(Cc2ccc(F)cc2)OCCCN2CCOCC2)O1 -US05631257,1,CC(=O)CBr.CN1CCN(c2nc3ccccc3o2)CC1>>CC(=O)C[N+]1(C)CCN(c2nc3ccccc3o2)CC1 -US08633182B2,6,COC(=O)[C@@H]1C[C@H]1c1ccc(OCc2ccccc2)cc1OC>>COC(=O)[C@@H]1C[C@H]1c1ccc(O)cc1OC -US20080312231A1,6,COC(=O)C1Cc2ccccc2N1S(=O)(=O)c1ccc(OC)cc1>>COc1ccc(S(=O)(=O)N2c3ccccc3CC2C(=O)O)cc1 -US20110257176A1,1,CC(C)N.COC(=O)CBr>>COC(=O)CNC(C)C -US20060229330A1,1,CC(O)CN.COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N>>COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCNCC(C)O)CC2)nc1N -US20120238549A1,2,CC[C@@]1(O)CC[C@@]2(Cc3ccccc3)c3ccc(C(=O)OC)cc3CCC[C@H]2C1.Nc1ccccc1N>>CC[C@@]1(O)CC[C@@]2(Cc3ccccc3)c3ccc(C(=O)Nc4ccccc4N)cc3CCC[C@H]2C1 -US08575154B2,2,CC(C)c1ccc(C(=O)O)cc1.CO>>COC(=O)c1ccc(C(C)C)cc1 -US20090264336A1,2,Cc1csc(N)n1.O=C(O)c1cc(Oc2ncc(C(=O)N3CCC3)cc2Cl)cc(O[C@H]2CCOC2)c1>>Cc1csc(NC(=O)c2cc(Oc3ncc(C(=O)N4CCC4)cc3Cl)cc(O[C@H]3CCOC3)c2)n1 -US08569535B2,1,CC(C)Br.COC(=O)C1(NC(=O)c2cccc(C)c2O)Cc2cccc3cccc(c23)C1>>COC(=O)C1(NC(=O)c2cccc(C)c2OC(C)C)Cc2cccc3cccc(c23)C1 -US05739345,1,Cn1c(CO)nc2ccc(-c3ccccc3)nc21.O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1>>Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2ccc(-c3ccccc3)nc21 -US06605626B2,2,Nc1ccc(Cl)cc1.O=C(Cl)c1ccccc1[N+](=O)[O-]>>O=C(Nc1ccc(Cl)cc1)c1ccccc1[N+](=O)[O-] -US20120122854A1,1,O=C(CBr)Nc1ccc(-n2ccccc2=O)cc1F.O=C(NC1CNc2ccccc21)c1ccc(Cl)s1>>O=C(CN1CC(NC(=O)c2ccc(Cl)s2)c2ccccc21)Nc1ccc(-n2ccccc2=O)cc1F -US20070027185A1,7,COCOc1cc(C(C)C)ccc1C(=O)O>>COCOc1cc(C(C)C)ccc1CO -US20100227887A1,2,CCOC(=O)c1cc(C#N)cc(C)n1.COc1cccc(N)c1>>COc1cccc(NC(=O)c2cc(C#N)cc(C)n2)c1 -US04803294,6,CCCCCCCCCCCCCCCCCC(=O)c1ccc(C(=O)OC)c(Cl)c1>>CCCCCCCCCCCCCCCCCC(=O)c1ccc(C(=O)O)c(Cl)c1 -US07196199B2,7,O=C(C1=Cc2cccc(OC[C@@H](O)CN3CCC(c4ccc5ccccc5c4)CC3)c2OC1)N1CCOCC1>>O[C@H](COc1cccc2c1OCC(CN1CCOCC1)=C2)CN1CCC(c2ccc3ccccc3c2)CC1 -US07951824B2,2,CCOC(=O)c1cc(-c2cncnc2)cc(C)n1.Cn1ccc(N)n1>>Cc1cc(-c2cncnc2)cc(C(=O)Nc2ccn(C)n2)n1 -US04162325,2,CCOC(=O)CN.O=C(O)CN1CCCC1=O>>CCOC(=O)CNC(=O)CN1CCCC1=O -US20150065482A1,9,CCOC(=O)c1nc(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)c2n1CCCC2.N>>CN1CC[C@@](O)(C#Cc2cccc(-c3nc(C(N)=O)n4c3CCCC4)c2)C1=O -US20070293521A1,1,COC(=O)C1Cc2cc(N)ccc2O1.Fc1cnc(Cl)nc1Nc1cc2c(F)c(F)c1OCO2>>COC(=O)C1Cc2cc(Nc3ncc(F)c(Nc4cc5c(F)c(F)c4OCO5)n3)ccc2O1 -US20100087427A1,3,C#C[Si](C)(C)C.COCCCOc1cc(C(=O)OC)ccc1Br>>COCCCOc1cc(C(=O)OC)ccc1C#C[Si](C)(C)C -US20140100226A1,1,CC(C)Br.COc1ccc(-c2nc(CCC(=O)c3ccccc3OCCF)co2)cc1O>>COc1ccc(-c2nc(CCC(=O)c3ccccc3OCCF)co2)cc1OC(C)C -US20130230542A1,1,CCN(CCCl)c1ccccc1.Oc1cccc(O)c1>>CCN(CCOc1cccc(O)c1)c1ccccc1 -US20090118296A1,2,COC(=O)c1ccc(N2CC[C@H](Oc3ccccc3C(F)(F)F)C2)nn1.NN>>NNC(=O)c1ccc(N2CC[C@H](Oc3ccccc3C(F)(F)F)C2)nn1 -US20150166480A1,3,CC(C)(F)CN1CCC(COc2ccc(Br)c(C#N)c2)CC1.CCOC(=O)c1ccc(B(O)O)cc1F>>CCOC(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)F)CC3)cc2C#N)cc1F -US20140155477A1,2,CCc1cccc(CC)c1S(=O)(=O)Cl.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCc1cccc(CC)c1S(=O)(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090318477A1,9,CC(C)OC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(Br)cc2F)CC1.N#C[Cu]>>CC(C)OC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(C#N)cc2F)CC1 -US20120329818A1,2,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.CC(C)(C)c1cccc(N)c1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cccc(C(C)(C)C)c2)CC1 -US20090209596A1,6,CC(C)(C)[Si](C)(C)OC(C(=O)c1ccccc1)c1ccncc1>>O=C(c1ccccc1)C(O)c1ccncc1 -US08008501B2,1,Cc1onc(-c2ccccc2)c1NC(=O)c1cc(Cl)nc2ccc(Br)cc12.Nc1cccc(O)c1>>Cc1onc(-c2ccccc2)c1NC(=O)c1cc(Nc2cccc(O)c2)nc2ccc(Br)cc12 -US04045568,7,O=C(CCCn1ccnc1)c1ccc(Cl)cc1>>OC(CCCn1ccnc1)c1ccc(Cl)cc1 -US20140343037A1,1,CC1(C)CC(=O)c2c(C(F)F)nn(-c3ccc(C#N)c(Br)c3)c2C1.NC1CCOCC1>>CC1(C)CC(=O)c2c(C(F)F)nn(-c3ccc(C#N)c(NC4CCOCC4)c3)c2C1 -US20070259879A1,1,CI.CO>>COC -US20040058965A1,6,COC(=O)Cc1cccc(OCc2ccc(OC)c(OCc3nc(-c4ccccc4)oc3C)c2)c1>>COc1ccc(COc2cccc(CC(=O)O)c2)cc1OCc1nc(-c2ccccc2)oc1C -US08106079B2,2,CNc1cc(OC)ccc1[N+](=O)[O-].O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>COc1ccc([N+](=O)[O-])c(N(C)C(=O)COc2ccc(CC3SC(=O)NC3=O)cc2)c1 -US20100204196A1,2,COc1cc(N2CCCNCC2)ccc1[N+](=O)[O-].CS(=O)(=O)Cl>>COc1cc(N2CCCN(S(C)(=O)=O)CC2)ccc1[N+](=O)[O-] -US20090131446A1,3,Brc1cnc(NC2CCC2)c2ncnn12.CC1(C)OB(c2coc(C(N)=O)c2)OC1(C)C>>NC(=O)c1cc(-c2cnc(NC3CCC3)c3ncnn23)co1 -US20140057895A1,1,CI.O=[N+]([O-])c1cc(O)ccc1F>>COc1ccc(F)c([N+](=O)[O-])c1 -US20070082896A1,1,CCOC(=O)C1CCNCC1.CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](Nc2ncc(OCCBr)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)C1CCN(CCOc2cnc(N[C@H]3C[C@@H](CC)N(C(=O)OCC)c4ccc(C(F)(F)F)cc43)nc2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US07196104B2,1,C1=COCCC1.OCCCNc1cccc(Br)n1>>Brc1cccc(NCCCOC2CCCCO2)n1 -US05536700,1,C#CCBr.Cn1nc(-c2cc3c(cc2F)NC(=O)CO3)c(Cl)c1C(F)(F)F>>C#CCN1C(=O)COc2cc(-c3nn(C)c(C(F)(F)F)c3Cl)c(F)cc21 -US20150099737A1,1,CC(C)(C)OC(=O)N1C2CCC1CN(c1ccc(N)nc1)C(=O)C2.CN(C)C(=O)c1cc2cnc(Cl)nc2n1C1CCC1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CC5CCC(CC4=O)N5C(=O)OC(C)(C)C)cn3)nc2n1C1CCC1 -US20050124616A1,3,CSc1nc(NC2CCCC2)n2nc(-c3ccccc3)c(Br)c2n1.OB(O)c1ccnc(F)c1>>CSc1nc(NC2CCCC2)n2nc(-c3ccccc3)c(-c3ccnc(F)c3)c2n1 -US07999006B2,6,COC(=O)C(C)(C)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1>>CC(C)(C(=O)O)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US20140288066A1,3,CC1(C)OB(c2ccc(NC(=O)NC3CC3)cc2)OC1(C)C.CC1c2c(nc(Cl)nc2N2CCOC[C@@H]2C)CS1(=O)=O>>CC1c2c(nc(-c3ccc(NC(=O)NC4CC4)cc3)nc2N2CCOC[C@@H]2C)CS1(=O)=O -US20130089512A1,6,O=c1[nH]c2cnc(-c3cnc4ccc(F)cn34)nc2n1C1CCC2(CC1)OCCO2>>O=C1CCC(n2c(=O)[nH]c3cnc(-c4cnc5ccc(F)cn45)nc32)CC1 -US20100016337A1,2,NC1CC1.O=C(O)CNc1nc(-c2ccc(F)cc2)cs1>>O=C(CNc1nc(-c2ccc(F)cc2)cs1)NC1CC1 -US20090131468A1,3,C#CC(C)(C)O.NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)cc1>>CC(C)(O)C#Cc1ccc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cc1 -US08148380B2,7,COC(=O)c1nc(NC(=O)NCc2cccc(F)c2)sc1C(C)C>>CC(C)c1sc(NC(=O)NCc2cccc(F)c2)nc1CO -US08048893B2,6,FC(F)(F)Oc1ccc(-c2cn(CCN3CCCCC3)nc2OCc2ccccc2)cc1>>Oc1nn(CCN2CCCCC2)cc1-c1ccc(OC(F)(F)F)cc1 -US04370343,2,CCCCCCCCCCCCC(C)C1(C(=O)O)CO1.NCCO>>CCCCCCCCCCCCC(C)C1(C(=O)NCCO)CO1 -US08598156B2,3,CC(C)(C)OC(=O)N1CCc2cc(B3OC(C)(C)C(C)(C)O3)ccc21.Cn1nc(Br)c2c(N)ncnc21>>Cn1nc(-c2ccc3c(c2)CCN3C(=O)OC(C)(C)C)c2c(N)ncnc21 -US20140135336A1,1,CCOC(=O)c1cnn(C)c1Br.Oc1ccccc1>>CCOC(=O)c1cnn(C)c1Oc1ccccc1 -US05276025,2,CNOC.NS(=O)(=O)c1cc(C(=O)O)c(Cl)s1>>CON(C)C(=O)c1cc(S(N)(=O)=O)sc1Cl -US08916555B2,1,NC(=O)c1c(Nc2ccc(C(=O)O)cc2)n[nH]c1N.O=Cc1ccc(O)cc1>>NC(=O)c1c(Nc2ccc(C(=O)O)cc2)n[nH]c1N=Cc1ccc(O)cc1 -US07230022B2,3,CC(C)(C)OC(=O)N1CCCC(=O)C1.Fc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCCC(=Cc2ccc(F)cc2)C1 -US20100063047A1,1,Cc1csc2nccc(Br)c12.NCCc1ccc(Cl)cc1>>Cc1csc2nccc(NCCc3ccc(Cl)cc3)c12 -US04251539,1,CCOP(OCC)OCC.Cc1cc(CCl)on1>>CCOP(=O)(Cc1cc(C)no1)OCC -US20130245000A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Cl)nc2)CC1.CS(=O)(=O)c1cnc2[nH]ccc2c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(-n3ccc4cc(S(C)(=O)=O)cnc43)nc2)CC1 -US04574010,2,CS(=O)(=O)Cl.Cc1nc(Br)[nH]c1C(=O)OC(C)C>>Cc1nc(Br)n(S(C)(=O)=O)c1C(=O)OC(C)C -US20060217424A1,6,CCc1c(CN(C)C)cccc1OC>>CCc1c(O)cccc1CN(C)C -US20130072679A1,2,CN1C(=O)CCc2cc(-c3cncc(O[C@H]4CCNC4)c3)ccc21.Cn1cc(C(=O)O)cn1>>CN1C(=O)CCc2cc(-c3cncc(O[C@H]4CCN(C(=O)c5cnn(C)c5)C4)c3)ccc21 -US07884244B2,7,O=C(O)C=Cc1ccc(F)cc1>>O=C(O)CCc1ccc(F)cc1 -US07446222B2,2,CCCC(=O)Cl.COC(=O)c1cc(N)cc(-c2ccccc2Br)c1>>CCCC(=O)Nc1cc(C(=O)OC)cc(-c2ccccc2Br)c1 -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)c1cc(Cl)ccc1F>>Cc1nc(NC(=O)c2cc(Cl)ccc2F)sc1C(=O)NCc1ccccc1 -US20060116356A1,2,NCCP(=O)(O)O.O=C(Cl)OCc1ccccc1>>O=C(NCCP(=O)(O)O)OCc1ccccc1 -US20030065193A1,2,Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)O)cc1.N[C@@H](Cc1ccccc1)C(=O)O>>Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2ccccc2)C(=O)O)cc1 -US07666888B2,2,O=C(O)c1ncoc1-c1ccccc1.O=C(c1ccc(F)cc1)C1CCNCC1>>O=C(c1ccc(F)cc1)C1CCN(C(=O)c2ncoc2-c2ccccc2)CC1 -US08765730B2,9,Cc1cc(C(=O)C[C@H](c2ccccc2)c2ccccc2C)ccn1.NO>>Cc1cc(/C(C[C@H](c2ccccc2)c2ccccc2C)=N/O)ccn1 -US20070287715A1,6,CCOC(=O)c1cc2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1>>CC(C)Oc1ccc(-n2c(C(=O)O)cc3cc(-c4ccc(C(C)(C)C)cc4)ccc32)cc1 -US04758577,1,C1=Cc2ccccc2C(C2CCNCC2)c2ccccc21.CN(C)c1ccc(C=O)cc1>>CN(C)c1ccc(CN2CCC(C3c4ccccc4C=Cc4ccccc43)CC2)cc1 -US20140364436A1,3,C#Cc1ccc(NC(C)C)nn1.CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(I)c3)cc2C(F)(F)F)CC1>>CC(C)Nc1ccc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)ccc2Cl)nn1 -US20060293341A1,6,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](Nc2nc(-c3ccccn3)cs2)CC1>>NC[C@@H]1CC[C@@H](Nc2nc(-c3ccccn3)cs2)CC1 -US20110046147A1,4,COc1ccc(C(=O)CC(=O)c2ccc(OC)cc2)cc1.NN>>COc1ccc(-c2cc(-c3ccc(OC)cc3)[nH]n2)cc1 -US20140056849A1,2,CC(C)O.O=C(Cl)OCCl>>CC(C)OC(=O)OCCl -US04731471,1,CC(=O)[O-].COc1cc2c(c(Cl)c1Cl)C(=O)C(CCCl)C2>>COc1cc2c(c(Cl)c1Cl)C(=O)C(CCOC(C)=O)C2 -US20100016282A1,1,CC(C)(C)OC(=O)CCN(CC=O)C(=O)OCc1ccccc1.COC(=O)[C@@H](N)CCOCc1ccccc1>>COC(=O)[C@H](CCOCc1ccccc1)NCCN(CCC(=O)OC(C)(C)C)C(=O)OCc1ccccc1 -US05010083,9,COC(=O)CC1c2cc(OC)ccc2NC(=O)C1C(=O)OC>>COC(=O)CC1CC(=O)Nc2ccc(OC)cc21 -US20150051144A1,2,C1COCCN1.Cc1cc(C(Cc2ccccc2)=NOCc2ccc(C(F)(F)F)cc2)ccc1OCC(=O)O>>Cc1cc(C(Cc2ccccc2)=NOCc2ccc(C(F)(F)F)cc2)ccc1OCC(=O)N1CCOCC1 -US20080286231A1,2,COc1ccc(N=C=S)cc1OC.Cc1cncn1CCCCN>>COc1ccc(NC(=S)NCCCCn2cncc2C)cc1OC -US06469010B1,1,BrCCCc1ccccc1.c1ccc(Oc2ccc(C3CCNCC3)cc2)cc1>>c1ccc(CCCN2CCC(c3ccc(Oc4ccccc4)cc3)CC2)cc1 -US20050153996A1,3,O=C(O)Cc1ccc(Br)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>O=C(O)Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US06352985B1,6,CCCCS(=O)(=O)NC(=O)c1ccc([N+](=O)[O-])c(NC(C)=O)c1>>CCCCS(=O)(=O)NC(=O)c1ccc([N+](=O)[O-])c(N)c1 -US20090264435A1,1,CCC(=O)CC.Clc1ccc(N2CCNCC2)cc1Cl>>CCC(CC)N1CCN(c2ccc(Cl)c(Cl)c2)CC1 -US20060160814A1,1,COc1cc2nncc(Br)c2cc1OC.c1ccc2c(c1)CCNC2>>COc1cc2nncc(N3CCc4ccccc4C3)c2cc1OC -US08148407B2,3,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2cncc(Br)c2)SC[C@H]1OC(C)=O.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cncc(O[C@@H]3SC[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)c2)cc1 -US20040235905A1,9,O=[N+]([O-])c1ccc(C2CC(O)c3cc(O)ccc3O2)cc1>>O=[N+]([O-])c1ccc(C2CCc3cc(O)ccc3O2)cc1 -US05807859,3,O=Cc1cccc([N+](=O)[O-])c1.O=c1[nH]c2c(n3ccnc13)Cc1ccccc1-2>>O=c1[nH]c2c3ccccc3c(=Cc3cccc([N+](=O)[O-])c3)c2n2ccnc12 -US20120172333A1,9,N#Cc1c(O)c2c(cc(Cl)n2-c2ccc(Br)cc2)[nH]c1=O.[NH4+]>>N#Cc1c(O)c2c(cc(Cl)n2-c2ccc(N)cc2)[nH]c1=O -US20080207621A1,2,Nc1ccc(S(N)(=O)=O)cc1.O=C=NC12CC3CC(CC(C3)C1)C2>>NS(=O)(=O)c1ccc(NC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 -US20060173050A1,3,CC(C)C[Zn+].N#Cc1c(N)cc(N)nc1Br>>CC(C)Cc1nc(N)cc(N)c1C#N -US08703805B2,3,CS(=O)(=O)c1cccc(B(O)O)c1.FC(F)(F)c1cc(-c2ccccc2C(F)(F)F)n(-c2ccc(Br)cc2)n1>>CS(=O)(=O)c1cccc(-c2ccc(-n3nc(C(F)(F)F)cc3-c3ccccc3C(F)(F)F)cc2)c1 -US20100022476A1,1,COc1cc(OCCCl)c2c(Cl)ncnc2c1.Nc1cc(CC(=O)O)[nH]n1>>COc1cc(OCCCl)c2c(Nc3cc(CC(=O)O)[nH]n3)ncnc2c1 -US20090306388A1,1,CC(C)CN.Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C>>Cc1nc(Cl)c([N+](=O)[O-])c(NCC(C)C)c1C -US09056859B2,1,CCOC(=O)c1coc2cc(Br)ccc12.O=C1NC(=O)c2ccccc21>>CCOC(=O)c1coc2cc(N3C(=O)c4ccccc4C3=O)ccc12 -US06458948B1,1,Clc1nc(Oc2ccccc2)nc(Oc2ccccc2)n1.OC1CN2CCC1CC2>>OC1C[N+]2(c3nc(Oc4ccccc4)nc(Oc4ccccc4)n3)CCC1CC2 -US20080139572A1,2,CCOC(=O)CC(OCC)OCC.O=C(OCc1ccccc1)N1CCNCC1>>CCOC(CC(=O)N1CCN(C(=O)OCc2ccccc2)CC1)OCC -US20030195354A1,1,COc1ccc(CCNC(=O)C(=CO)c2ccc(C)cc2)cc1OC.FCBr>>COc1ccc(CCNC(=O)C(=COCF)c2ccc(C)cc2)cc1OC -US09045478B2,1,CCOC(=O)c1cnn2ccc(Br)cc12.Fc1cc2c(c(C3CCCN3)c1)OCCO2>>CCOC(=O)c1cnn2ccc(N3CCCC3c3cc(F)cc4c3OCCO4)cc12 -US20050113397A1,1,CC(C)(C)OC(=O)NCC=O.CN[C@H]1CCN(Cc2ccccc2)C1>>CN(CCNC(=O)OC(C)(C)C)[C@H]1CCN(Cc2ccccc2)C1 -US20080103183A1,2,CC(C)C(=O)C(N)Cc1ccccc1.O=C=NC1C2CC3CC(C2)CC1C3>>CC(C)C(=O)C(Cc1ccccc1)NC(=O)NC1C2CC3CC(C2)CC1C3 -US05591862,7,COC(=O)C=Cc1ccc(OCc2nc(-c3ccccc3)c(C)s2)cc1>>Cc1sc(COc2ccc(/C=C/CO)cc2)nc1-c1ccccc1 -US07585979B2,1,ClCCCCCBr.N#Cc1ccc(O)cc1>>N#Cc1ccc(OCCCCCCl)cc1 -US20060089394A1,6,CCCCC(Oc1ccc(CC(=O)OC)cc1)c1cccc(-c2ccc(C(F)(F)F)cc2)n1>>CCCCC(Oc1ccc(CC(=O)O)cc1)c1cccc(-c2ccc(C(F)(F)F)cc2)n1 -US04962109,2,CC(C)(C)c1ncc(C(C(=O)O)C(C)(C)C)cn1.COCc1c(F)c(F)c(CO)c(F)c1F>>COCc1c(F)c(F)c(COC(=O)C(c2cnc(C(C)(C)C)nc2)C(C)(C)C)c(F)c1F -US20090111995A1,3,Brc1ccccc1-c1nnn(C2CCCCO2)n1.CCOC(OCC)c1ccc(Br)cc1>>CCOC(OCC)c1ccc(-c2ccccc2-c2nnn(C3CCCCO3)n2)cc1 -US20100016289A1,1,O=C1CCCNCC1.OB(O)c1ccccc1>>O=C1CCCN(c2ccccc2)CC1 -US20130045986A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Fc1cc(Br)cc2nc(C3CCNCC3)oc12>>CC(C)(C)OC(=O)N1CCC(c2nc3cc(Br)cc(F)c3o2)CC1 -US20090137580A1,2,CC(C)(O)CC(=O)O.NCCn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21>>CC(C)(O)CC(=O)NCCn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21 -US20140275067A1,1,CC(C)(C)OC(=O)NC1(CN)CCCC1.Clc1ncc(Br)c(Cl)n1>>CC(C)(C)OC(=O)NC1(CNc2nc(Cl)ncc2Br)CCCC1 -US20110118236A1,1,COC(=O)CCCBr.FC(F)(F)c1n[nH]c2c1CCCC2>>COC(=O)CCCn1nc(C(F)(F)F)c2c1CCCC2 -US20140249137A1,1,Nc1cc(C2CC2)[nH]n1.O=[N+]([O-])c1cnc(-c2ccccc2)nc1Cl>>O=[N+]([O-])c1cnc(-c2ccccc2)nc1Nc1cc(C2CC2)[nH]n1 -US04871771,8,CCCCCCCCCC/C=C/c1ccccc1CO>>CCCCCCCCCC/C=C/c1ccccc1C=O -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)nc3)c(F)c2)OC1(C)C.O=S(=O)(CCCS(=O)(=O)C1CCCCC1)c1ccccc1Br>>Nc1ncc(-c2ccc(-c3ccccc3S(=O)(=O)CCCS(=O)(=O)C3CCCCC3)cc2F)cn1 -US07309720B2,1,CCOC(=O)[C@H](Cc1ccc(CCO)cc1)OCC.CS(=O)(=O)Oc1ccc(O)cc1>>CCOC(=O)[C@H](Cc1ccc(CCOc2ccc(OS(C)(=O)=O)cc2)cc1)OCC -US20070010556A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H]1CCCCN(C(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)N[C@H]1CCCCN(C(=O)OCc2ccccc2)C1 -US07429609B2,2,CC(=O)OC(C)=O.Cc1ccc(F)cc1N>>CC(=O)Nc1cc(F)ccc1C -US20080188528A1,6,COC(=O)c1cccn(Cc2ccc(Br)cc2)c1=O>>O=C(O)c1cccn(Cc2ccc(Br)cc2)c1=O -US09156827B2,3,C=O.CS(=O)(=O)N1CCNCC1.O=C1COc2cc(O)ccc21>>CS(=O)(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1 -US20150274696A1,7,O=[N+]([O-])c1cc2nsnc2cc1F>>Nc1cc2nsnc2cc1F -US08008298B2,3,Brc1cnc2[nH]ccc2n1.CC(C)(CCCC#N)C(=O)Cl>>CC(C)(CCCC#N)C(=O)c1c[nH]c2ncc(Br)nc12 -US07893058B2,3,CC1(C)OB(c2ccc(C(N)=O)cc2)OC1(C)C.CN1CCN(c2ccc(Nc3ncc(Br)n4ccnc34)cc2Cl)CC1>>CN1CCN(c2ccc(Nc3ncc(-c4ccc(C(N)=O)cc4)n4ccnc34)cc2Cl)CC1 -US20090286768A1,1,OB(O)c1ccccc1.Oc1ccc(Br)c(OC(F)(F)F)c1>>FC(F)(F)Oc1cc(Oc2ccccc2)ccc1Br -US20070049589A1,6,COC(=O)Cc1c(C(=O)NC(C)(C)C)[nH]c2ccc(Br)cc12>>CC(C)(C)NC(=O)c1[nH]c2ccc(Br)cc2c1CC(=O)O -US20090186876A1,2,CCOC(=O)c1cnc(N2CCNCC2)c(Cl)c1.O=C=Nc1ccc(Cl)c(Cl)c1>>CCOC(=O)c1cnc(N2CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)c(Cl)c1 -US20110301353A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNCCN1CCc2[nH]cc(C)c2C1=O>>CCN(CCN1CCc2[nH]cc(C)c2C1=O)C(=O)OC(C)(C)C -US20110092461A1,1,Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2ccc(O)cn2)c1.FC(F)(F)CI>>Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2ccc(OCC(F)(F)F)cn2)c1 -US20080193413A1,2,CCCC1(CCC)C(=O)C(C(=O)OCC)=C(O)c2ccccc21.Nc1ccccc1S(N)(=O)=O>>CCCC1(CCC)C(=O)C(C(=O)Nc2ccccc2S(N)(=O)=O)=C(O)c2ccccc21 -US20140349993A1,1,C1CCNC1.Nc1nccc(Cl)n1>>Nc1nccc(N2CCCC2)n1 -US20150152118A1,7,CC1(C)C(=O)NCCN1Cc1ccccc1>>CC1(C)CNCCN1Cc1ccccc1 -US05773463,1,CC(C)=O.N[C@H]1Cc2ccccc2[C@H]1Oc1ccc(Oc2ccc(F)cc2)cc1>>CC(C)N[C@H]1Cc2ccccc2[C@H]1Oc1ccc(Oc2ccc(F)cc2)cc1 -US20130012706A1,1,COCCl.COCn1nnc2c(C(N)=O)ncn2c1=O>>COCNC(=O)c1ncn2c(=O)n(COC)nnc12 -US20130158075A1,6,COC(=O)C1CCC(c2ncc(-c3ccc(NC(=O)Nc4c(Cl)cccc4C(F)(F)F)cc3)s2)CC1>>O=C(Nc1ccc(-c2cnc(C3CCC(C(=O)O)CC3)s2)cc1)Nc1c(Cl)cccc1C(F)(F)F -US20130018030A1,1,C[C@@]1(C2CCNCC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1.FC(F)(F)c1cnc(Cl)nc1>>C[C@@]1(C2CCN(c3ncc(C(F)(F)F)cn3)CC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1 -US06693123B2,2,COC(=O)[C@H](CCSC)NC(=O)c1ccc(C(=O)O)cc1-c1ccccc1.Nc1ccccn1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(C(=O)Nc2ccccn2)cc1-c1ccccc1 -US20140274930A1,3,C[Mg+].O=C[C@H]1O[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1>>C[C@H](O)[C@H]1O[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1 -US20080275043A1,6,COc1ccc(-c2ccc(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)c(C)c1>>Cc1cc(O)ccc1-c1ccc(CC2CCN(C3CCCCC3)C2=O)c(Cl)c1 -US06706751B2,1,BrCCCCCBr.O=C(Oc1ccc(Cl)cc1)N1CCCc2cc(O)ccc21>>O=C(Oc1ccc(Cl)cc1)N1CCCc2cc(OCCCCCBr)ccc21 -US07053105B2,2,COCCN=C=S.Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(N)nc(-c3cccc(Cl)c3)c2c1>>COCCNC(=S)Nc1nc(-c2cccc(Cl)c2)c2cc(C(O)(c3ccc(Cl)cc3)c3cncn3C)ccc2n1 -US07572809B2,1,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.Nc1ccccn1>>COc1ccc2c(Nc3ccccn3)nc(Nc3cc(C)[nH]n3)cc2c1 -US20080300260A1,1,CCCC(=O)c1ccc(N)cc1.Cc1nn(-c2ccccc2)c(C)c1C=O>>CCCC(=O)c1ccc(NCc2c(C)nn(-c3ccccc3)c2C)cc1 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.Cc1ccc(C=CC(=O)O)cc1>>Cc1ccc(C=CC(=O)N2C[C@H](CC(C)C)NC(=O)[C@@H]2CC(C)C)cc1 -US20150246922A1,3,Cc1cc(Br)c2c(c1)cc1n2CCNC1=O.OB(O)c1ccc(F)cc1>>Cc1cc(-c2ccc(F)cc2)c2c(c1)cc1n2CCNC1=O -US20080090805A1,3,Fc1ccc([Zn+])nc1.O=C(NN1CCCCC1)c1cccc2c1C(Cl)=Nc1ccccc1S2>>O=C(NN1CCCCC1)c1cccc2c1C(c1ccc(F)cn1)=Nc1ccccc1S2 -US20130090347A1,2,CSCC(=O)O.Nc1ccc(Br)cn1>>CSCC(=O)Nc1ccc(Br)cn1 -US09073864B2,6,CCOC(=O)[C@@H]1CCCN(C(=O)c2ccc(NC(CCC(F)(F)F)c3ccc(-c4ccc(C(F)(F)F)cn4)cc3C)cc2)C1>>Cc1cc(-c2ccc(C(F)(F)F)cn2)ccc1C(CCC(F)(F)F)Nc1ccc(C(=O)N2CCC[C@@H](C(=O)O)C2)cc1 -US20040204586A1,2,N#Cc1c(N2CCNCC2)c2cc(Cl)ccc2n(Cc2ccccc2)c1=O.O=C(Cl)c1ccco1>>N#Cc1c(N2CCN(C(=O)c3ccco3)CC2)c2cc(Cl)ccc2n(Cc2ccccc2)c1=O -US20140057931A1,8,COc1ccc2c3c1O[C@@H]1[C@]34CCN(CC3CC3)[C@H](C2)[C@]42CC[C@@]1(OC)[C@@H](CSCc1ccccc1)C2.O=C(OO)c1cccc(Cl)c1>>COc1ccc2c3c1O[C@@H]1[C@]34CCN(CC3CC3)[C@H](C2)[C@]42CC[C@@]1(OC)[C@@H](CS(=O)Cc1ccccc1)C2 -US20110124665A1,6,CC(C)(C)OC(=O)CO[C@@H]1C=C[C@@H](N2C(=O)c3ccccc3C2=O)C1>>CC(C)(C)OC(=O)COC1C=CC(N)C1 -US05532240,1,CC(=O)c1c(CCCl)sc2c1CCN(C(C)=O)C2.Fc1ccc2c(C3CCNCC3)noc2c1>>CC(=O)c1c(CCN2CCC(c3noc4cc(F)ccc34)CC2)sc2c1CCN(C(C)=O)C2 -US20130005744A1,1,CO.O=c1[nH]c(I)ccc1OCc1ccccc1>>Cn1c(I)ccc(OCc2ccccc2)c1=O -US08354441B2,2,CC(C)(C)OC(=O)N1[C@@H](CCc2ccc(N)cc2)COC1(C)C.O=C(O)c1ccc(Cl)cn1>>CC(C)(C)OC(=O)N1[C@@H](CCc2ccc(NC(=O)c3ccc(Cl)cn3)cc2)COC1(C)C -US07230020B2,2,NCCc1cccs1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>O=C(NCCc1cccs1)c1cc(Cl)cc(Cl)c1 -US08008298B2,3,CC1(C(=O)c2c[nH]c3ncc(Br)nc23)CCCC1.CC1(C)OB(c2cccc(N3CCOCC3)c2)OC1(C)C>>CC1(C(=O)c2c[nH]c3ncc(-c4cccc(N5CCOCC5)c4)nc23)CCCC1 -US20080161187A1,2,NCc1ccncc1.O=S(=O)(Cl)c1ccc(I)cc1>>O=S(=O)(NCc1ccncc1)c1ccc(I)cc1 -US20100216810A1,2,CC(C)(C#N)c1cccc(C(=O)O)c1Cl.N#Cc1c(Oc2ccc(F)c(N)c2)ccc2nc(NC(=O)C3CC3)sc12>>CC(C)(C#N)c1cccc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3C#N)ccc2F)c1Cl -US08183262B2,1,Cc1cc(-c2ccc(Cl)cc2)cc(Cl)n1.Ic1c[nH]cn1>>Cc1cc(-c2ccc(Cl)cc2)cc(-n2cnc(I)c2)n1 -US20130116234A1,6,COC(=O)c1c(C(C)C)nc2ccc(Cl)cc2c1-c1cccc(OC(F)(F)F)c1>>CC(C)c1nc2ccc(Cl)cc2c(-c2cccc(OC(F)(F)F)c2)c1C(=O)O -US20120015911A1,9,COc1ccc2c(c1OC)CCC2=O.NO>>COc1ccc2c(c1OC)CCC2=NO -US20100099892A1,9,CCOC(=O)C12CCC(NCC(=O)N3C[C@@H](F)C[C@H]3C(N)=O)(CC1)CC2>>CCOC(=O)C12CCC(NCC(=O)N3C[C@@H](F)C[C@H]3C#N)(CC1)CC2 -US20040220229A1,2,CCS(=O)(=O)c1ccc(O)c(N)c1.O=C(O)c1cc2cc(F)ccc2[nH]1>>CCS(=O)(=O)c1ccc(O)c(NC(=O)c2cc3cc(F)ccc3[nH]2)c1 -US04788204,10,Cc1nc(-c2ccccc2)cc2ccccc12.O=C1CCC(=O)N1Br>>BrCc1nc(-c2ccccc2)cc2ccccc12 -US05756754,2,CN(C)C(=O)Cl.Oc1ccc2c(C3CNCCN3c3ccncc3)noc2c1>>CN(C)C(=O)Oc1ccc2c(C3CNCCN3c3ccncc3)noc2c1 -US04533655,6,C[C@H](C(=O)NCCCc1ccc(F)cc1)N(C)C(=O)OC(C)(C)C>>CN[C@H](C)C(=O)NCCCc1ccc(F)cc1 -US08344027B2,1,BrCCCCCCCCCOC1CCCCO1.OCCc1ccccc1>>c1ccc(CCOCCCCCCCCCOC2CCCCO2)cc1 -US04510313,4,N=C(N)NC(N)=S.O=C(CBr)C(=O)c1c[nH]cn1>>N=C(N)Nc1nc(C(=O)c2c[nH]cn2)cs1 -US20140249132A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCOc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C)c1Br>>CCOc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C)c1B1OC(C)(C)C(C)(C)O1 -US08802684B2,9,Clc1nc(Cl)c2ncn(C3CCCCO3)c2n1.N>>Nc1nc(Cl)nc2c1ncn2C1CCCCO1 -US07244713B2,6,C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cc(C#C[Si](C)(C)C)c2c(N)ncnc21>>C#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@@]2(C)O)c2ncnc(N)c12 -US05514680,7,Nc1c([N+](=O)[O-])cc(F)cc1[N+](=O)[O-]>>Nc1cc(F)cc([N+](=O)[O-])c1N -US20140018380A1,5,Brc1ccc2c(c1)CCN2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCc2cc(Br)ccc21 -US05576340,1,COC(=O)Cc1ccc(OCC(C)=O)cc1.NCC(O)c1cccc(Cl)c1>>COC(=O)Cc1ccc(OCC(C)NCC(O)c2cccc(Cl)c2)cc1 -US20150119362A1,2,CCOC(=O)/C(CC)=C(/C)N.CCOC(=O)CC(=O)Cl>>CCOC(=O)CC(=O)N/C(C)=C(/CC)C(=O)OCC -US20130109661A1,1,C1CCNC1.CC1CCCN1c1cccc(Nc2cc(-c3cccc(C=O)c3)nn3ccnc23)n1>>CC1CCCN1c1cccc(Nc2cc(-c3cccc(CN4CCCC4)c3)nn3ccnc23)n1 -US20090264445A1,2,CC(C)(O)Cn1ccc(N)n1.O=C(O)[C@H](CC1CCCCC1)N1CC(Oc2c(F)ccc(Cl)c2F)=CC1=O>>CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCC2)N2CC(Oc3c(F)ccc(Cl)c3F)=CC2=O)n1 -US05880135,1,CCCN(c1ccc2[nH]ccc2c1)c1nc(-c2ccc(OC)cc2Cl)c(C)s1.COC(=O)CBr>>CCCN(c1ccc2c(ccn2CC(=O)OC)c1)c1nc(-c2ccc(OC)cc2Cl)c(C)s1 -US07713994B2,7,COCC1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>COCC1CCN(c2ccc(N)cc2)CC1 -US20080027112A1,1,CCOC(=O)CCCCCBr.COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1O>>CCOC(=O)CCCCCOc1c(OC)ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc12 -US20100130737A1,2,COC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1.O=C(O)c1ccc2nc(-c3ccc(Cl)cc3)c(Cl)n2c1>>COC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)c1ccc2nc(-c3ccc(Cl)cc3)c(Cl)n2c1 -US07705047B2,3,CC(=O)COc1cc(C#N)ccc1Oc1ccc(Cl)cc1Cl.N.[C-]#N>>CC(N)(C#N)COc1cc(C#N)ccc1Oc1ccc(Cl)cc1Cl -US20040106645A1,3,CCC[Zn+].O=c1cc(NC2CCN(CC=Cc3ccccc3)CC2)c2cc(Br)ccc2o1>>CCCc1ccc2oc(=O)cc(NC3CCN(CC=Cc4ccccc4)CC3)c2c1 -US20140336382A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3cc(F)cc(F)c3)cc2)c2c(N)ncnc21>>Nc1ncnc2c1c(-c1ccc(Oc3cc(F)cc(F)c3)cc1)nn2C[C@H]1CCCN1 -US20040254188A1,1,C1CCCNCC1.O=C1CCc2cc(F)ccc21>>O=C1CCc2cc(N3CCCCCC3)ccc21 -US04518597,8,CC1(C)OC(=O)Nc2ccc(OCCCCSc3ccccc3)cc21.OO>>CC1(C)OC(=O)Nc2ccc(OCCCCS(=O)c3ccccc3)cc21 -US20080269193A1,1,N#Cc1c(F)cc(Br)cc1F.N[C@H]1CCOC1>>N#Cc1c(F)cc(Br)cc1N[C@H]1CCOC1 -US20110207723A1,5,CC(C)(C)OC(=O)NC1=N[C@@]2(c3cc(Br)ccc3F)CO[C@@H](CF)C[C@H]2CS1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=N[C@@]2(c3cc(Br)ccc3F)CO[C@@H](CF)C[C@H]2CS1 -US05624941,2,Nc1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2Cl)n1.O=CO>>O=CNc1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2Cl)n1 -US07435735B2,2,COCN.O=C(O)CN(CC(=O)O)C(=O)OCc1ccccc1>>COCNC(=O)CN(CC(=O)O)C(=O)OCc1ccccc1 -US07256204B2,1,CN(C)CCC1CCc2cc(O)ccc2C1.ClCc1cc2ccccc2o1>>CN(C)CCC1CCc2cc(OCc3cc4ccccc4o3)ccc2C1 -US20090048258A1,3,CN(C)c1ccc(B(O)O)cc1.O=C(CCC(=O)c1ccc2c(c1)CCO2)Nc1cc(Cl)cc(-c2ccccc2)n1>>CN(C)c1ccc(-c2cc(NC(=O)CCC(=O)c3ccc4c(c3)CCO4)nc(-c3ccccc3)c2)cc1 -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)O)CC1.FC(F)(F)C1CCCN1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)N2CCCC2C(F)(F)F)CC1 -US09040516B2,2,Cc1c(-c2c(S(=O)(=O)O)cnn2-c2ccc(C#N)cc2)c(=O)n(C)c(=O)n1-c1cccc(C(F)(F)F)c1.N[C@H](CO)c1ccccc1>>Cc1c(-c2c(S(=O)(=O)N[C@H](CO)c3ccccc3)cnn2-c2ccc(C#N)cc2)c(=O)n(C)c(=O)n1-c1cccc(C(F)(F)F)c1 -US08404673B2,2,COc1cccc(C)c1C(=O)O.N[C@@H]1CCC[C@@H]1N1CCCC1>>COc1cccc(C)c1C(=O)N[C@@H]1CCC[C@@H]1N1CCCC1 -US04499089,1,CCN.CCSC1=C(C#N)C(c2ccccc2)(c2ccccc2)C(=O)N1CCCBr>>CCNCCCN1C(=O)C(c2ccccc2)(c2ccccc2)C(C#N)=C1SCC -US20080139558A1,2,Cc1cnoc1C(=O)O.O=c1cc(CNc2cccc(Cl)c2)c2cccc(F)c2[nH]1>>Cc1cnoc1C(=O)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1 -US07514409B2,2,COC(=O)[C@@H]1C[C@H](O)CN1.N#Cc1cccc(S(=O)(=O)Cl)c1>>COC(=O)[C@@H]1C[C@H](O)CN1S(=O)(=O)c1cccc(C#N)c1 -US20050054686A1,1,Cc1nc(C#Cc2cccc(C#N)c2)c[nH]1.ClCc1cncc(Cl)c1>>Cc1nc(C#Cc2cccc(C#N)c2)cn1Cc1cncc(Cl)c1 -US07332497B2,1,COc1cc(-c2nn(C3CCNC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C.Cc1n[nH]cc1C=O>>COc1cc(-c2nn(C3CCN(Cc4c[nH]nc4C)C3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C -US20050250753A1,1,NNc1ccc(Cl)cc1.O=C1CCc2ccc(Br)cc21>>Clc1ccc(NN=C2CCc3ccc(Br)cc32)cc1 -US20020193614A1,2,COC(=O)Cl.COc1ccc(CNC(=O)c2cc(C#N)ccc2N[C@H]2CCNC2)cc1OC>>COC(=O)N1CC[C@H](Nc2ccc(C#N)cc2C(=O)NCc2ccc(OC)c(OC)c2)C1 -US20080312164A1,9,NCC(c1ccccc1)c1ccccc1.S=C(Cl)Cl>>S=C=NCC(c1ccccc1)c1ccccc1 -US08759363B2,3,COc1cc(B(O)O)cc(OC)c1OC.Cc1ccc(Nc2nc(Cl)nc3ccccc23)cc1>>COc1cc(-c2nc(Nc3ccc(C)cc3)c3ccccc3n2)cc(OC)c1OC -US08552186B2,1,COCCN(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.COc1cc2c(cc1N)CCN(CC(=O)N(C)C)CC2>>COCCN(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(CC(=O)N(C)C)CC3)ncc1Cl -US04348410,1,N=C(N)NC[C@@H]1CC[C@@H](C(=O)O)CC1.Oc1ccc2ccccc2c1>>N=C(N)NC[C@@H]1CC[C@@H](C(=O)Oc2ccc3ccccc3c2)CC1 -US20130217664A1,7,COc1cc(-c2c(C)nn(C)c2C)ncc1[N+](=O)[O-]>>COc1cc(-c2c(C)nn(C)c2C)ncc1N -US20090181968A1,6,COC(=O)COc1ccc(NC(=O)c2ccc(C)c3ccccc23)c(C(=O)NCC2CCOCC2)n1>>Cc1ccc(C(=O)Nc2ccc(OCC(=O)O)nc2C(=O)NCC2CCOCC2)c2ccccc12 -US04851526,1,CCN(CC)CCCl.Oc1ccc(-n2ccnc2)cc1>>CCN(CC)CCOc1ccc(-n2ccnc2)cc1 -US20040192686A1,1,ClCCN1CCOCC1.Nc1nc2ccc(O)cc2[n+]([O-])n1>>Nc1nc2ccc(OCCN3CCOCC3)cc2[n+]([O-])n1 -US09139580B2,3,CC(C)(NC(=O)N1CCN2CCC1CC2)c1ccc(F)c(Br)c1.OB(O)c1ccccc1>>CC(C)(NC(=O)N1CCN2CCC1CC2)c1ccc(F)c(-c2ccccc2)c1 -US08658636B2,6,COC(=O)c1c(CN2CCC(=O)C(C)C2)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(=O)(=O)C(C)C)cc12>>CC1CN(Cc2c(-c3cccc(C(F)(F)F)c3)nc3ccc(S(=O)(=O)C(C)C)cc3c2C(=O)O)CCC1=O -US20080249150A1,1,COc1ccc(CCl)cc1.c1nc[nH]n1>>COc1ccc(Cn2cncn2)cc1 -US08222408B2,1,CC(=O)CCl.O=[N+]([O-])c1ccccc1O>>CC(=O)COc1ccccc1[N+](=O)[O-] -US20100168103A1,1,ClCc1ccccc1.OCCNCCO>>OCCN(CCO)Cc1ccccc1 -US08110687B2,2,CC(C)(C)c1cccc(NC(=O)C2CCc3ccc(Oc4ccnc(N)c4)cc3C2)c1.CCN=C=O>>CCNC(=O)Nc1cc(Oc2ccc3c(c2)CC(C(=O)Nc2cccc(C(C)(C)C)c2)CC3)ccn1 -US04226892,8,C=C(C)CC(O)C1=C(C)CCCC1(C)C>>C=C(C)CC(=O)C1=C(C)CCCC1(C)C -US08461328B2,7,N#C[C@@H]1CC[C@@H](Nc2c([N+](=O)[O-])cnc3c2ccn3S(=O)(=O)c2ccccc2)CC1>>N#C[C@@H]1CC[C@@H](Nc2c(N)cnc3c2ccn3S(=O)(=O)c2ccccc2)CC1 -US20140371199A1,2,CC(C)(C)OC(=O)NCCC1CCNCC1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1>>CC(C)(C)OC(=O)NCCC1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4c3)cc2)CC1 -US20110015119A1,6,COC(=O)c1ccc(OCCN2CCOCC2)cc1>>O=C(O)c1ccc(OCCN2CCOCC2)cc1 -US08865909B2,1,CCCCCCCCC/C=C1\SC(=O)NC1=O.CCOC(=O)CBr>>CCCCCCCCC/C=C1\SC(=O)N(CC(=O)OCC)C1=O -US20100249163A1,6,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccn(C)c(=O)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)C2CNCCC2(O)c2ccn(C)c(=O)c2)C2CC2)cc(OCCOC)c1 -US20120207729A1,7,CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)cc(Cc3ccc([N+](=O)[O-])cc3)cc2s1>>CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)cc(Cc3ccc(N)cc3)cc2s1 -US20100160309A1,3,C=C(C)B1OC(C)(C)C(C)(C)O1.CCCCOc1nccc2nc(OS(=O)(=O)C(F)(F)F)c3ccc(F)cc3c12>>C=C(C)c1nc2ccnc(OCCCC)c2c2cc(F)ccc12 -US08394799B2,1,CCOC(=O)CCl.Oc1ccc(Br)cc1Cl>>CCOC(=O)COc1ccc(Br)cc1Cl -US08809538B2,1,CCOc1nc(C(=O)NCC2CCNCC2)cc(N)c1C#N.O=Cc1cnc(-c2cccs2)s1>>CCOc1nc(C(=O)NCC2CCN(Cc3cnc(-c4cccs4)s3)CC2)cc(N)c1C#N -US20150246048A1,2,N#CC1CCNC1.O=S(=O)(Cl)Cl>>N#CC1CCN(S(=O)(=O)Cl)C1 -US04590193,1,O=[N+]([O-])c1ccccc1CCBr.c1ccc(N2CCNCC2)cc1>>O=[N+]([O-])c1ccccc1CCN1CCN(c2ccccc2)CC1 -US20100041892A1,2,CC(C)Oc1cc(CCC(=O)O)n(Cc2ccc(Cl)cc2Cl)n1.Cc1ccccc1S(N)(=O)=O>>Cc1ccccc1S(=O)(=O)NC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1Cl -US20090124596A1,2,Nc1ccccc1.O=C(O)c1cccc(-n2c(=O)n(C3CCC(NC(=O)c4cn5ccccc5n4)CC3)c(=O)c3cc(F)cnc32)c1>>O=C(Nc1ccccc1)c1cccc(-n2c(=O)n([C@@H]3CC[C@H](NC(=O)c4cn5ccccc5n4)CC3)c(=O)c3cc(F)cnc32)c1 -US07338960B2,3,CCCCC[Mg+].O=Cc1cccc(-c2ccc(C(F)(F)F)cc2)n1>>CCCCCC(O)c1cccc(-c2ccc(C(F)(F)F)cc2)n1 -US20090048224A1,6,CC(C)(C)OC(=O)NC1CCc2cc(CN3CCCCC3)ccc2C1>>NC1CCc2cc(CN3CCCCC3)ccc2C1 -US20100197910A1,1,CC1Sc2c(C(=O)O)c(=O)c3cc(F)c(N4CCNCC4)cc3n21.Cc1oc(=O)oc1CBr>>Cc1oc(=O)oc1CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)c2n3C(C)S2)CC1 -US20020193599A1,1,OCCCBr.c1ccc(C2CCNCC2)cc1>>OCCCN1CCC(c2ccccc2)CC1 -US20100256134A1,2,CCOC(=O)c1cnn2c(O)c(C(=O)O)cnc12.Fc1cccc2c1C1(CCNCC1)CO2>>CCOC(=O)c1cnn2c(O)c(C(=O)N3CCC4(CC3)COc3cccc(F)c34)cnc12 -US06331506B1,7,COC(=O)c1ccc([N+](=O)[O-])cc1S(=O)(=O)NC(C)(C)C>>COC(=O)c1ccc(N)cc1S(=O)(=O)NC(C)(C)C -US20050065189A1,6,CCCCCc1sc(C(=O)OCC)nc1-c1ccccc1>>CCCCCc1sc(C(=O)O)nc1-c1ccccc1 -US08003785B2,2,CCN1CCC(N)CC1.CCOc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>CCOc1cc(C(=O)NC2CCN(CC)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20040116328A1,5,CC#CCn1c(N2CCNCC2)nc2cn[nH]c(=O)c21.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2cn[nH]c(=O)c21 -US20080161289A1,1,C1COCCN1.Clc1ccc(-c2nc3c(s2)CCN(C2CCC2)CC3)cn1>>c1cc(N2CCOCC2)ncc1-c1nc2c(s1)CCN(C1CCC1)CC2 -US20150266867A1,1,C#CCNC(=O)CBr.CN(C)C>>C#CCNC(=O)C[N+](C)(C)C -US07179823B1,1,CCOC(=O)Cc1c[nH]nc1-c1ccccc1.Cc1oc(-c2ccco2)nc1COc1ccc(CCl)cn1>>CCOC(=O)Cc1cn(Cc2ccc(OCc3nc(-c4ccco4)oc3C)nc2)nc1-c1ccccc1 -US08735584B2,9,O=C(Cc1cc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)n[nH]1)Nc1ccc(F)c(F)c1>>O=C(Cc1cc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)n[nH]1)Nc1cccc(F)c1 -US07132436B2,2,CS(=O)(=O)c1sc(Cl)c2c1-c1nc(N)sc1CC2.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>CS(=O)(=O)c1sc(Cl)c2c1-c1nc(NS(=O)(=O)c3ccc(-c4ccccc4)cc3)sc1CC2 -US20110160180A1,2,CCNCC(=O)NCCF.O=C(O)c1ccc2c(c1)c1c(n2C2CCC2)CCC(C2CCOCC2)C1>>CCN(CC(=O)NCCF)C(=O)c1ccc2c(c1)c1c(n2C2CCC2)CCC(C2CCOCC2)C1 -US20040167224A1,2,CC(C)(C)OC(=O)N1CCC(F)(C(=O)O)CC1.CNOC>>CON(C)C(=O)C1(F)CCN(C(=O)OC(C)(C)C)CC1 -US04137234,7,O=C(O)c1csc(Cc2ccccc2)n1>>OCc1csc(Cc2ccccc2)n1 -US08901141B2,7,COC(=O)c1cccc2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl>>OCc1cccc2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl -US20100286138A1,1,C1COCCN1.Cc1cc(Br)cc(C)c1NC(=O)CC(C)(C)C>>Cc1cc(N2CCOCC2)cc(C)c1NC(=O)CC(C)(C)C -US20150119362A1,1,C[S-].Clc1nc(Cl)c2c(n1)CCC2>>CSc1nc(Cl)c2c(n1)CCC2 -US07482448B2,6,CC[C@H](NC(=O)OC(C)(C)C)C(O)c1nnc(-c2ccc(OC(F)(F)F)cc2)o1>>CCC(N)[C@H](O)c1nnc(-c2ccc(OC(F)(F)F)cc2)o1 -US20110046169A1,2,Cc1ccccc1-n1cccc(C(=O)O)c1=O.Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3c2)c(F)c1>>Cc1ccccc1-n1cccc(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c(F)c2)c1=O -US05292627,1,CCCCCSCCCCl.Nc1n[nH]c(S)n1>>CCCCCSCCCSc1nc(N)n[nH]1 -US08513270B2,2,Cc1ncc(N)cc1I.O=C(Cl)c1cccc(C(F)(F)F)c1>>Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1I -US20080242687A1,1,COc1ccccc1Oc1c(Cl)nc(-c2ncccn2)nc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1.OCCO>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(-c2ncccn2)nc1OCCO -US20140378433A1,1,C[C@@H]1COCCN1.O=[N+]([O-])c1ccc(Cl)nc1>>C[C@@H]1COCCN1c1ccc([N+](=O)[O-])cn1 -US20060247250A1,1,Brc1ccc(OCCN2CCCC2)cc1.CCOC(=O)c1cnc(N)nc1C(F)(F)F>>CCOC(=O)c1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1C(F)(F)F -US20090226398A1,3,CC(C)(C)OCc1ccc(B(O)O)cc1.Fc1cccc(-c2nc3cnn(Cc4ccc(Cl)nn4)cc-3n2)c1F>>CC(C)(C)OCc1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)nn2)cc1 -US20140080756A1,2,COc1ccc(CC(=O)O)nc1.N#Cc1ccc(-c2ccc3c(c2)CC[C@H]3N2CC3(CCNCC3)C2)nc1>>COc1ccc(CC(=O)N2CCC3(CC2)CN([C@@H]2CCc4cc(-c5ccc(C#N)cn5)ccc42)C3)nc1 -US20100069381A1,2,CC(=O)OC(C)C(=O)O.NNC(=O)c1ccc2occ(-c3cccc(OC(F)(F)F)c3)c2c1>>CC(=O)OC(C)C(=O)NNC(=O)c1ccc2occ(-c3cccc(OC(F)(F)F)c3)c2c1 -US20150011527A1,3,C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(Br)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)OC(C)(C)C.OB(O)c1ccc(O)cc1>>C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(-c3ccc(O)cc3)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)OC(C)(C)C -US20070249670A1,6,COC(=O)C1(NC(=O)c2sc(-c3ccc(OC)cc3)cc2NC(=O)Nc2c(C)cc(C)cc2C)CCCCC1>>COc1ccc(-c2cc(NC(=O)Nc3c(C)cc(C)cc3C)c(C(=O)NC3(C(=O)O)CCCCC3)s2)cc1 -US20030119807A1,2,CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1.CNCc1ccccc1>>CN(Cc1ccccc1)C(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1 -US06369069B1,1,COCCOc1ccc(F)cc1CBr.CS(=O)(=O)c1cc(Br)ccc1CN>>COCCOc1ccc(F)cc1CNCc1ccc(Br)cc1S(C)(=O)=O -US20150158858A1,1,CC=O.COc1ccc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2ccc(CNC(C(=O)O[C@H]3CN4CCC3CC4)c3ccccc3)s2)cc1OC>>CCN(Cc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC)c(OC)c2)s1)C(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1 -US20150274718A1,1,CCCI.O=c1ccc(Br)c[nH]1>>CCCn1cc(Br)ccc1=O -US20100120793A1,3,Fc1cnc(Cl)nc1.OB(O)c1ccc(O)cc1>>Oc1ccc(-c2ncc(F)cn2)cc1 -US20130072506A1,1,NCc1ccccc1.Nc1nc2c(Cl)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>Nc1nc2c(NCc3ccccc3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O -US20040186091A1,7,COc1ccc(N)c(C(=O)O)c1>>COc1ccc(N)c(CO)c1 -US07618978B2,8,CCCN(C)C(=O)c1cc(CO)cc(C(=O)OCC)c1>>CCCN(C)C(=O)c1cc(C=O)cc(C(=O)OCC)c1 -US08129373B2,8,O=C(Nc1ccc(N2CCOCC2=O)cc1)[C@H]1C[C@@H](O)CN1C(=O)Nc1ccc(Cl)cc1>>O=C1C[C@H](C(=O)Nc2ccc(N3CCOCC3=O)cc2)N(C(=O)Nc2ccc(Cl)cc2)C1 -US20120225857A1,3,CCN(C)S(=O)(=O)c1ccc([Sn](C)(C)C)nc1.Nc1ncc(Br)cc1-c1cc2c(s1)C(=O)NCC2>>CCN(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc4c(s3)C(=O)NCC4)c2)nc1 -US20130029964A1,9,N.O=C(O)c1ccc([N+](=O)[O-])c(Br)c1>>NC(=O)c1ccc([N+](=O)[O-])c(Br)c1 -US20140057899A1,9,C=C[C@@H](Cn1cc(I)c2c(Cl)ncnc21)NC(=O)OC(C)(C)C.N>>C=C[C@@H](Cn1cc(I)c2c(N)ncnc21)NC(=O)OC(C)(C)C -US05332739,7,Cn1c(N2CCN(CCCOc3ccc([N+](=O)[O-])cc3)CC2)cc(=O)n(C)c1=O>>Cn1c(N2CCN(CCCOc3ccc(N)cc3)CC2)cc(=O)n(C)c1=O -US20070249670A1,7,COC(=O)[C@@H](NC(=O)c1ccc(-c2cc(F)cc(F)c2)cc1[N+](=O)[O-])C1CCCCC1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2cc(F)cc(F)c2)cc1N)C1CCCCC1 -US05466706,2,CN.Cc1ccc(-c2nc3n(C)c4ccccc4n3c2CC(=O)O)cc1>>CNC(=O)Cc1c(-c2ccc(C)cc2)nc2n(C)c3ccccc3n12 -US20060111349A1,2,CC(C)(C)OC(=O)N1CCc2ccc(N)cc21.O=C(O)c1sccc1NCc1ccnc2ccccc12>>CC(C)(C)OC(=O)N1CCc2ccc(NC(=O)c3sccc3NCc3ccnc4ccccc34)cc21 -US20140200225A1,2,CC(C)(C)OC(=O)NC1CCC(N)CC1.CC(C)(C)OC(=O)NCc1cc(F)c(Oc2cc(Oc3ccc(C#N)cc3)cc(C(=O)O)c2)c(F)c1>>CC(C)(C)OC(=O)NCc1cc(F)c(Oc2cc(Oc3ccc(C#N)cc3)cc(C(=O)NC3CCC(NC(=O)OC(C)(C)C)CC3)c2)c(F)c1 -US20120101110A1,1,Cc1cc(C)nc(N2CCC3(CCCNC3=O)CC2)n1.Cc1noc(-c2ccccc2CBr)n1>>Cc1cc(C)nc(N2CCC3(CCCN(Cc4ccccc4-c4nc(C)no4)C3=O)CC2)n1 -US06451821B1,2,CC(C)(C)N=C=S.C[C@H](O)CN>>C[C@H](O)CNC(=S)NC(C)(C)C -US20090203665A1,3,CC(C)(C)OC(=O)N1Cc2cc(Cl)c(C3=CCOCC3)cc2C1.CCCC[Sn](CCCC)(CCCC)C1CC1>>CC(C)(C)OC(=O)N1Cc2cc(C3=CCOCC3)c(C3CC3)cc2C1 -US05206235,2,CC(C)(CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3C(=O)O)cc2)C1=O)NC(=O)OCc1ccccc1.NCCO>>CC(C)(CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3C(=O)NCCO)cc2)C1=O)NC(=O)OCc1ccccc1 -US08415345B2,1,CC(C)CN.O=S(=O)(Nc1cccc(-c2nc(N3CCOCC3)sc2-c2ccnc(Cl)n2)c1Cl)c1c(F)cccc1F>>CC(C)CNc1nccc(-c2sc(N3CCOCC3)nc2-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2Cl)n1 -US05500361,2,CCCCCCCCCCCCCCN.O=C(CI)OC(=O)CI>>CCCCCCCCCCCCCCNC(=O)CI -US05334600,2,CCOC(=O)Cl.NCCc1cccc(Br)c1>>CCOC(=O)NCCc1cccc(Br)c1 -US08481042B2,2,CSSC(C)(C)CCC(=O)O.OCc1cc(OCCN2CCNCC2)cc(CO)n1>>CSSC(C)(C)CCC(=O)N1CCN(CCOc2cc(CO)nc(CO)c2)CC1 -US20120289501A1,6,CC(C)[Si](Oc1ccc2c(c1)O[C@@H](c1ccccc1)CC2)(C(C)C)C(C)C>>Oc1ccc2c(c1)O[C@@H](c1ccccc1)CC2 -US20030176405A1,1,C1=COCCC1.COc1ccc2c(c1)CCC1=C2C(=O)C[C@@]2(C)[C@H]1CC[C@@H]2O>>COc1ccc2c(c1)CCC1=C2C(=O)C[C@@]2(C)[C@H]1CC[C@@H]2OC1CCCCO1 -US04125732,1,COC(=O)C(Br)c1ccc(OCC(C)Oc2ccc(C(C)(C)C)cc2)cc1.Oc1cccc(C(F)(F)F)c1>>COC(=O)C(Oc1cccc(C(F)(F)F)c1)c1ccc(OCC(C)Oc2ccc(C(C)(C)C)cc2)cc1 -US20100168101A1,6,NNC(=O)COc1ccc(C(=O)OCc2ccccc2)cc1>>NNC(=O)COc1ccc(C(=O)O)cc1 -US20070010511A1,1,COCCCCl.O=[N+]([O-])c1ccccc1O>>COCCCOc1ccccc1[N+](=O)[O-] -US03960871,1,CCCCCCCCCCCCCCCCCCC(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CCS1.O=C(O)CCCN1CCSCC1>>CCCCCCCCCCCCCCCCCCC(C)c1cc(OC(=O)CCCN2CCSCC2)c2c(c1)OC(C)(C)C1=C2CCS1 -US20100210630A1,6,CN(Cc1ccc(Oc2ccc(Br)cc2)cc1)C[C@H]1CCCN1C(=O)OC(C)(C)C>>CN(Cc1ccc(Oc2ccc(Br)cc2)cc1)C[C@H]1CCCN1 -US20100010015A1,2,COC(=O)Cl.COc1ccc2c(c1)NC(=O)C21CCCn2cncc21>>COC(=O)N1C(=O)C2(CCCn3cncc32)c2ccc(OC)cc21 -US20080255094A1,6,CC(C)(C)OC(=O)N1CCS[C@H]1C(=O)N[C@H](c1ccccc1)c1ccccn1>>O=C(N[C@H](c1ccccc1)c1ccccn1)[C@H]1NCCS1 -US07666866B2,1,CCI.COC(=O)c1ccc(O)cc1O>>CCOc1ccc(C(=O)OC)c(O)c1 -US20050256203A1,6,COC(=O)c1cccc(C2(O)CCCCC2CN(C)C)c1>>CN(C)CC1CCCCC1(O)c1cccc(C(=O)O)c1 -US05661159,6,COC(=O)CCCSC(SCCC(=O)N(C)C)c1ccc2oc(-c3ccc4ccc(Cl)cc4n3)cc2c1>>CN(C)C(=O)CCSC(SCCCC(=O)O)c1ccc2oc(-c3ccc4ccc(Cl)cc4n3)cc2c1 -US08026260B2,6,CCOC(=O)c1cnc(N(C)CCc2ccccc2)s1>>CN(CCc1ccccc1)c1ncc(C(=O)O)s1 -US20110118234A1,7,N#CC1(c2ccccc2)CCCC1>>NCC1(c2ccccc2)CCCC1 -US20100249124A1,1,CC(c1ccc(Br)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(c2ccc(C(C)C(O)(c3ccc4c(c3)N(C)C(=O)CO4)C(F)(F)F)c(Cl)c2)CC1 -US06380218B1,1,CC(C)(O)C1CC=C(CO)CC1.O=C1NC(=O)c2ccccc21>>CC(C)(O)C1CC=C(CN2C(=O)c3ccccc3C2=O)CC1 -US20060276464A1,2,CC(C)c1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)Cl.NC1CCN(C(=O)c2ccccc2F)CC1>>CC(C)c1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)NC1CCN(C(=O)c2ccccc2F)CC1 -US20050031541A1,2,CCCO.NCC(=O)CCC(=O)O>>CCCOC(=O)CCC(=O)CN -US07338974B2,6,C=CCC(C(=O)OC)N1CCCC1=O>>C=CCC(C(=O)O)N1CCCC1=O -US20150057286A1,1,C[O-].Cc1nn(C)c2c(-c3cc(NC(=O)c4ccc(Cl)cn4)nc(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)c3)nc(Cl)nc12>>COc1nc(-c2cc(NC(=O)c3ccc(Cl)cn3)nc(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)c2)c2c(n1)c(C)nn2C -US20090118318A1,1,CC(C)(C)OC(=O)N1CCC2(CCNCC2)CC1.O=Cc1ccccc1Oc1ccccc1>>CC(C)(C)OC(=O)N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1 -US20090054405A1,2,CN(C)c1cc(-c2ccc3nc(N)sc3c2)cnc1Cl.O=C(Cl)Oc1ccccc1>>CN(C)c1cc(-c2ccc3nc(NC(=O)Oc4ccccc4)sc3c2)cnc1Cl -US20150023913A1,2,C=CCO[C@@](C)(C=C)CO.O=C(Cl)c1ccccc1>>C=CCO[C@@](C)(C=C)COC(=O)c1ccccc1 -US20080262056A1,1,CI.O=C1Nc2c(F)cccc2C1=O>>CN1C(=O)C(=O)c2cccc(F)c21 -US06211215B1,1,ClCc1coc(/C=C/C2CCCCC2)n1.Oc1ccc(CCCn2ccnc2)cc1>>C(=C/C1CCCCC1)\c1nc(COc2ccc(CCCn3ccnc3)cc2)co1 -US04831041,2,CN=C=O.Cc1cccc(N)c1CO>>CNC(=O)Nc1cccc(C)c1CO -US20040122244A1,1,CC(C)Br.COc1c(C)c(Cc2ccc(O)c(C=O)c2)c(OC)c(OC)c1OC>>COc1c(C)c(Cc2ccc(OC(C)C)c(C=O)c2)c(OC)c(OC)c1OC -US20130331378A1,7,COC(=O)c1cccc(C(=O)c2c(-c3ccc(C)cc3)nn3cc(OC)ccc23)n1>>COC(=O)c1cccc(C(O)c2c(-c3ccc(C)cc3)nn3cc(OC)ccc23)n1 -US08841455B2,6,CCOC(=O)c1cnc2cc(OCC3COC(C)(C)O3)ccn12>>CC1(C)OCC(COc2ccn3c(C(=O)O)cnc3c2)O1 -US20050054712A1,1,Cc1cc(C2(O)C(=O)Nc3ccccc32)cc(C)c1O[Si](C)(C)C(C)(C)C.OB(O)c1cccc(OC(F)(F)F)c1>>Cc1cc(C2(O)C(=O)N(c3cccc(OC(F)(F)F)c3)c3ccccc32)cc(C)c1O[Si](C)(C)C(C)(C)C -US04033996,1,CCCCCC(CCCCl)OC(C)=O.CCOC(=O)CCCCCCNS(C)(=O)=O>>CCCCCC(CCCN(CCCCCCC(=O)OCC)S(C)(=O)=O)OC(C)=O -US08153814B2,3,CCOCn1nccc1B1OC(C)(C)C(C)(C)O1.COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(Oc3ccc(OC(F)(F)F)cc3I)c(C#N)c2)c(OC)c1>>CCOCn1nccc1-c1cc(OC(F)(F)F)ccc1Oc1ccc(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2ncns2)cc1C#N -US08846658B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1=NC(c2cccc(Br)c2)(C(F)F)COC1>>CC(C)(C)OC(=O)NC1=NC(c2cccc(Br)c2)(C(F)F)COC1 -US20030013721A1,2,Cc1ccc(S(C)(=O)=O)cc1N.O=C(Cl)CCl>>Cc1ccc(S(C)(=O)=O)cc1NC(=O)CCl -US20090233937A1,2,CC(C)(C)C(=O)OC(=O)C(C)(C)C.NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(F)c3)c21>>CC(C)(C)C(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(F)c3)c21 -US20150148542A1,2,COc1cc(C(=O)O)ccc1Br.FC1CNC1>>COc1cc(C(=O)N2CC(F)C2)ccc1Br -US20050171125A1,3,COc1ccnc(CCc2nc3cc(I)cnc3[nH]2)c1.N#Cc1ccc(Br)cc1>>COc1ccnc(CCc2nc3cc(-c4ccc(C#N)cc4)cnc3[nH]2)c1 -US20080312234A1,3,CCOC(=O)C=Cc1ccc(C(F)(F)F)nc1Cl.OB(O)c1ccccc1>>CCOC(=O)C=Cc1ccc(C(F)(F)F)nc1-c1ccccc1 -US20060276433A1,7,O=[N+]([O-])c1ccccc1-c1cnco1>>Nc1ccccc1-c1cnco1 -US20090325953A1,3,O=C(Cl)c1c(F)cc(F)cc1F.O=C(O)c1ccc[nH]1>>O=C(O)c1cc(C(=O)c2c(F)cc(F)cc2F)c[nH]1 -US06133438,1,CI.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1>>CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O -US20130225673A1,1,CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1.CI>>CCc1oc2ccccc2c1C(=O)c1cc(Br)c(OC)c(Br)c1 -US05840724,6,COC(=O)c1ccc(OC(F)F)c(OC2CCCC2)c1>>O=C(O)c1ccc(OC(F)F)c(OC2CCCC2)c1 -US05204476,2,CCCCCCCCC(=O)Cl.CCCCCCCOc1ccc(-c2ccc(O)cn2)c(F)c1>>CCCCCCCCC(=O)Oc1ccc(-c2ccc(OCCCCCCC)cc2F)nc1 -USRE036138,1,CCCCCCCCCCCCBr.NCC(=O)O>>CCCCCCCCCCCCNCC(=O)O -US08168821B2,3,CCOC(=O)CC1(CCC(C=O)Cc2ccc(C(=O)OC)cc2)CC1.Oc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)CC1(CCC(/C=C/c2ccccc2O)Cc2ccc(C(=O)OC)cc2)CC1 -US05420164,2,CCc1cccc(CC)c1N=C=O.c1ccc(C2CCC(NCC3CCCCC3)CC2)cc1>>CCc1cccc(CC)c1NC(=O)N(CC1CCCCC1)C1CCC(c2ccccc2)CC1 -US06936736B2,2,CC(C)(C)N.O=C(O)c1cc(F)c(F)cc1F>>CC(C)(C)NC(=O)c1cc(F)c(F)cc1F -US20100034766A1,7,CC(=O)C=CC(C)(C)OC(C)C1CCCC(C)(C)C1>>CC(=O)CCC(C)(C)OC(C)C1CCCC(C)(C)C1 -US08748672B2,2,CC(C)(C)C(=O)Cl.OCC(F)(F)Br>>CC(C)(C)C(=O)OCC(F)(F)Br -US08283378B2,1,Cc1ccc(S(=O)[O-])cc1.N#CCBr>>Cc1ccc(S(=O)(=O)CC#N)cc1 -US20070190071A1,1,BrCCCBr.COC(=O)Cc1cccc(N)c1>>COC(=O)Cc1cccc(NCCCBr)c1 -US20030216429A1,1,CCOC(=O)c1cn(Cc2c(F)cccc2F)c2cc(Br)c(CBr)cc2c1=O.CNCc1ccccc1>>CCOC(=O)c1cn(Cc2c(F)cccc2F)c2cc(Br)c(CN(C)Cc3ccccc3)cc2c1=O -US20030225130A1,3,Nc1ccc(C(=O)c2ccccc2)cc1.O=C(CCCl)c1ccccc1>>Nc1ccc(C(=C(CCCl)c2ccccc2)c2ccccc2)cc1 -US20070105908A1,5,CC(C)(C)OC(=O)N1CCC(c2cnc(N)s2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(c2cnc(NC(=O)C(F)(F)F)s2)CC1 -US20120178765A1,1,CC(C)CBr.COC(=O)c1cc(O)cc(C(=O)OC)c1>>COC(=O)c1cc(OCC(C)C)cc(C(=O)OC)c1 -US07754742B2,2,CC(C)C(=O)c1ccc(OCc2ccc(CN)cc2)c(C(F)(F)F)c1O.Cn1cnc(C(=O)O)c1>>CC(C)C(=O)c1ccc(OCc2ccc(CNC(=O)c3cn(C)cn3)cc2)c(C(F)(F)F)c1O -US20020013496A1,2,COc1ccc(N)cc1O.O=S(=O)(Cl)c1c(F)c(F)c(F)c(F)c1Br>>COc1ccc(NS(=O)(=O)c2c(F)c(F)c(F)c(F)c2Br)cc1O -US03952001,1,CCCCCN(CCC)C(=O)Cl.CCS(=O)(=O)c1nc[nH]n1>>CCCCCN(CCC)C(=O)n1cnc(S(=O)(=O)CC)n1 -US20070155805A1,6,CCCOC(CCSc1ccc(OCC(=O)OCC)c(C)c1)c1sc2cc(C(F)(F)F)ccc2c1C>>CCCOC(CCSc1ccc(OCC(=O)O)c(C)c1)c1sc2cc(C(F)(F)F)ccc2c1C -US20050020505A1,2,CCOC(=O)C[C@@H](NC(=O)CN)c1cc(C)cc(C)c1O.O=C(O)c1cc(NC2=NCC(F)CN2)cc([N+](=O)[O-])c1>>CCOC(=O)C[C@@H](NC(=O)CNC(=O)c1cc(NC2=NCC(F)CN2)cc([N+](=O)[O-])c1)c1cc(C)cc(C)c1O -US08809371B2,9,CC(C)(C)OC(=O)N[C@@H]1CCCC[C@@H]1Nc1nc(Cl)c(C(N)=O)cc1F>>CC(C)(C)OC(=O)N[C@@H]1CCCC[C@@H]1Nc1nc(Cl)c(C#N)cc1F -US20110098311A1,7,O=C1CCCc2ccc([N+](=O)[O-])cc21>>O=[N+]([O-])c1ccc2c(c1)C(O)CCC2 -US08426420B2,6,COC(=O)[C@@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C1CCCCC1>>O=C(N[C@H](C(=O)O)C1CCCCC1)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1 -US20090181942A1,6,CCOC(=O)C[C@H]1S[C@H](c2cccc(F)c2F)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F>>O=C(O)C[C@H]1S[C@H](c2cccc(F)c2F)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F -US20120122840A1,6,COc1cc(N2CCC(C(=O)N3CCOCC3)CC2)ccc1Nc1nc(NC2CCCCC2)c2ncn(C3CCCCO3)c2n1>>COc1cc(N2CCC(C(=O)N3CCOCC3)CC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 -US20110065681A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1.COC(=O)c1cc(Br)cc(C(=O)OC)c1>>COC(=O)c1cc(C(=O)OC)cc(-c2ccc(C)cn2)c1 -US20080312231A1,2,CO.O=C(O)CC1NCCc2ccccc21>>COC(=O)CC1NCCc2ccccc21 -US20110281870A1,9,[N-]=[N+]=N[C@H]1CC[C@@H]2CN(Cc3ccccc3)C[C@H]12>>N[C@H]1CC[C@@H]2CN(Cc3ccccc3)C[C@H]12 -US07973026B2,1,CC(C)(C)OC(=O)c1cc2[nH]cc(C3CCCCC3)c2s1.COC(=O)CBr>>COC(=O)Cn1cc(C2CCCCC2)c2sc(C(=O)OC(C)(C)C)cc21 -US09035059B2,2,Nc1ccc(F)cc1.O=C(N1Cc2ccc(S(=O)(=O)Cl)cc2C1)C(F)(F)F>>O=C(N1Cc2ccc(S(=O)(=O)Nc3ccc(F)cc3)cc2C1)C(F)(F)F -US08138188B2,1,CI.Cc1ccc(O)cn1>>COc1ccc(C)nc1 -US20050277643A1,1,Clc1cccnc1Cl.FC(F)(F)c1ccc(Nc2ncnc3c2CCNC3)cc1>>FC(F)(F)c1ccc(Nc2ncnc3c2CCN(c2ncccc2Cl)C3)cc1 -US08263606B2,6,Cc1cc2c(cc1C)C1(CO2)C(=O)N(C(c2ccccc2)c2ccccc2)c2ccccc21>>Cc1cc2c(cc1C)C1(CO2)C(=O)Nc2ccccc21 -US05114949,1,O=S1(=O)c2cccc3cccc(c23)N1CCCl.c1ccc2c(CC3CCNCC3)c[nH]c2c1>>O=S1(=O)c2cccc3cccc(c23)N1CCN1CCC(Cc2c[nH]c3ccccc23)CC1 -US20100041891A1,6,CCOC(=O)c1cccc(-c2cccc3cc(CO)sc23)c1>>O=C(O)c1cccc(-c2cccc3cc(CO)sc23)c1 -US20100029605A1,9,Clc1cc(Cl)ncn1.NN>>NNc1cc(Cl)ncn1 -US20130150400A1,2,CNCc1oc2ccccc2c1C.O=C(O)/C=C/c1cnc2c(c1)CCC(=O)N2>>Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CCC(=O)N3)oc2ccccc12 -US20030219832A1,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(C(C)(C)C)cc2)=CCC3(C)C)cc1>>CC(C)(C)c1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 -US07553971B2,6,COc1ccc(Nc2ccc(CCNC[C@H](O)c3ccc(OCc4ccccc4)c4[nH]c(=O)ccc34)cc2)cc1-c1ccccc1>>COc1ccc(Nc2ccc(CCNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)cc2)cc1-c1ccccc1 -US06509329B1,3,CCOC(=O)CP(=O)(OCC)OCC.COc1cc(-c2cc(C=O)ccn2)cc(OC)c1OC>>CCOC(=O)C=Cc1ccnc(-c2cc(OC)c(OC)c(OC)c2)c1 -US20140011853A1,2,COC(=O)C1(N)CCC(F)(F)CC1.Cc1ccc(-c2ccc(F)cc2)cc1CC(=O)O>>COC(=O)C1(NC(=O)Cc2cc(-c3ccc(F)cc3)ccc2C)CCC(F)(F)CC1 -US20140378493A1,3,C=CCC[C@H](NC(=O)OCc1ccccc1)c1cc(C(F)(F)F)ccc1Br.C=Cc1cc(C)cc(C(F)(F)F)c1>>Cc1cc(/C=C/CC[C@@H](NC(=O)OCc2ccccc2)c2cc(C(F)(F)F)ccc2Br)cc(C(F)(F)F)c1 -US20080161366A1,1,COc1ccccc1N.O=[N+]([O-])c1ccccc1F>>COc1ccccc1Nc1ccccc1[N+](=O)[O-] -US08895613B2,6,CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(=O)C(F)F)[C@@H](NC(=O)OC(C)(C)C)C1>>CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(=O)C(F)F)[C@@H](N)C1 -US20090082434A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cc(F)cc(Br)c3O2)cc1.OB(O)c1ccccc1F>>Cc1ccc(S(=O)(=O)OCC2Cc3cc(F)cc(-c4ccccc4F)c3O2)cc1 -US05968985,6,COC(=O)c1cc(C(=O)OC)cc(-c2cc(Cl)sc2Cl)c1>>COC(=O)c1cc(C(=O)O)cc(-c2cc(Cl)sc2Cl)c1 -US05447949,1,CC(C)(C)C(=O)OCCl.CCCCc1ncc(C=O)[nH]1>>CCCCc1ncc(C=O)n1COC(=O)C(C)(C)C -US20060223843A1,3,N#Cc1cnc2ccc(C=O)nc2c1.O=C1CSC(NCc2cccs2)=N1>>N#Cc1cnc2ccc(C=C3SC(NCc4cccs4)=NC3=O)nc2c1 -US04704464,2,N[C@@H](Cc1ccccc1)C(=O)O.O=C(Cl)OCc1ccccc1>>O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCc1ccccc1 -US20130203728A1,2,CCN(C(=O)Oc1ccc(F)cc1)[C@@H]1CNC[C@H]1c1ccc(Cl)cc1.O=C(O)C1CCN(c2ccc(C(F)(F)F)cn2)CC1>>CCN(C(=O)Oc1ccc(F)cc1)[C@@H]1CN(C(=O)C2CCN(c3ccc(C(F)(F)F)cn3)CC2)C[C@H]1c1ccc(Cl)cc1 -US06924292B2,2,CC(=O)Cl.COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(Nc3cccnc3)c1)=NC(C)(C)C2>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(N(C(C)=O)c3cccnc3)c1)=NC(C)(C)C2 -US07812027B2,6,CC(C)(C)OC(=O)N[C@H]1C[C@@H](N2CCn3nc(C(F)(F)F)nc3C2)CO[C@@H]1c1cc(F)c(F)cc1F>>N[C@H]1C[C@@H](N2CCn3nc(C(F)(F)F)nc3C2)CO[C@@H]1c1cc(F)c(F)cc1F -US20110312974A1,2,CC(=O)Cl.CCOC(=O)Cc1cncc(-c2ccc(CN)cc2CN(Cc2ccccc2)C(=O)C2CC2)c1>>CCOC(=O)Cc1cncc(-c2ccc(CNC(C)=O)cc2CN(Cc2ccccc2)C(=O)C2CC2)c1 -US20080194647A1,3,C[Si](C)(C)C#Cc1cncc(C#N)c1.Fc1ccc(I)cc1Cl>>N#Cc1cncc(C#Cc2ccc(F)c(Cl)c2)c1 -US06005109,1,FC(F)(F)c1cccc(S)c1.N#CCCl>>N#CCSc1cccc(C(F)(F)F)c1 -US08278325B2,1,COC(=O)CBr.O=C1NC(=O)c2cc(Br)ccc21>>COC(=O)CN1C(=O)c2ccc(Br)cc2C1=O -US08314108B2,1,CC(C)(C)OC(=O)NCCCO.COc1cccc(O)c1-c1cc(Nc2cnc(C#N)cn2)n[nH]1>>COc1cccc(OCCCNC(=O)OC(C)(C)C)c1-c1cc(Nc2cnc(C#N)cn2)n[nH]1 -US20130341066A1,1,CCCCCCCCBr.CCCCCCCCOc1ccc(-c2ccc3[nH]c4ccc(-c5ccc(OCCCCCCCC)cc5)cc4c3c2)cc1>>CCCCCCCCOc1ccc(-c2ccc3c(c2)c2cc(-c4ccc(OCCCCCCCC)cc4)ccc2n3CCCCCCCC)cc1 -USRE045183E1,1,COC(=O)CS.O=C(Nc1ncc(Br)s1)N(C1CCCCC1)C1CCCCC1>>COC(=O)CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1 -US05977101,6,COC(=O)CC1Nc2ccc(C(=O)NCc3nc4ccccc4[nH]3)cc2CN(CCc2ccccc2)C1=O>>O=C(O)CC1Nc2ccc(C(=O)NCc3nc4ccccc4[nH]3)cc2CN(CCc2ccccc2)C1=O -US07067541B2,2,NCc1ccc(CN)cc1.O=C(Cl)OCc1ccccc1>>NCc1ccc(CNC(=O)OCc2ccccc2)cc1 -US20090186875A1,1,Clc1nc(N2CCN(c3ccccc3)CC2)nc2c1SCC2.NC1CCCCC1>>c1ccc(N2CCN(c3nc4c(c(NC5CCCCC5)n3)SCC4)CC2)cc1 -US20090118280A1,1,FC(F)(F)c1n[nH]c2c1CCCC2.N#CCc1ccc(Br)cc1>>N#CCc1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1 -US20150266874A1,2,CC(C)(C)N.C[Si](C)(C)CCOCn1cc(C(=O)O)c(-c2nc3c(s2)CCCC3)n1>>CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)nc1-c1nc2c(s1)CCCC2 -US20060241302A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.Fc1ccc(F)c(C(Sc2ccc(Cl)cc2)c2cc(Cl)ncc2Cl)c1>>CC(C)(C)OC(=O)N1CCC(Nc2cc(C(Sc3ccc(Cl)cc3)c3cc(F)ccc3F)c(Cl)cn2)CC1 -US20090099177A1,1,CC(C)CBr.Oc1ccc(Cl)cc1>>CC(C)COc1ccc(Cl)cc1 -US20150094306A1,1,CC(C)(C)[S@](N)=O.Cc1cc(C=O)ncc1OCCC(F)(F)F>>Cc1cc(/C=N/[S@@](=O)C(C)(C)C)ncc1OCCC(F)(F)F -US20090275574A1,1,N[C@@H]1CC2(CC[C@H]1O)OCCO2.O=C1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(N[C@@H]2CC3(CC[C@H]2O)OCCO3)CC1 -US20070179188A1,1,CO.COC(=O)c1cccc(CBr)c1>>COCc1cccc(C(=O)OC)c1 -US20070208036A1,1,CN.O=C(O)CCC(=O)c1ccc(Cl)c([N+](=O)[O-])c1>>CNc1ccc(C(=O)CCC(=O)O)cc1[N+](=O)[O-] -US08563565B2,1,COc1ccc(CNC(=O)c2cnn(C3CCOC3)c2-c2ccc(Br)cc2Cl)c(OC)c1>>COc1ccc(Cn2c(=O)c3cnn(C4CCOC4)c3c3ccc(Br)cc32)c(OC)c1 -US08859522B2,1,CNC(=O)c1cn[nH]c1.Nc1nc(F)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>CNC(=O)c1cnn(-c2nc(N)c3ncn([C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)c1 -US20060058380A1,1,Cc1ccccc1C(=O)c1ccc(N(C(=O)OC(C)Cl)c2ccc(F)cc2C)cc1Cl.O=C([O-])c1ccccn1>>Cc1ccccc1C(=O)c1ccc(N(C(=O)OC(C)OC(=O)c2ccccn2)c2ccc(F)cc2C)cc1Cl -US20110105472A1,1,FC(F)(F)c1cnc(Cl)nc1NC1CCC1.Nc1ccccc1>>FC(F)(F)c1cnc(Nc2ccccc2)nc1NC1CCC1 -US20070281943A1,2,NCc1cccnc1.O=C(O)c1ccc(Nc2ncc(Br)n3ccnc23)cc1>>O=C(NCc1cccnc1)c1ccc(Nc2ncc(Br)n3ccnc23)cc1 -US20100041892A1,7,CCOC(=O)CCc1ccc(OCc2ccco2)cc1Oc1ncc(C(F)(F)F)cc1Cl>>OCCCc1ccc(OCc2ccco2)cc1Oc1ncc(C(F)(F)F)cc1Cl -US03993660,2,CC(=O)Cl.Nc1ccc(Cl)cc1C(=O)c1ccccc1Cl>>CC(=O)Nc1ccc(Cl)cc1C(=O)c1ccccc1Cl -US20150266856A1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCN(Cc2ccccc2)CC1(F)F>>C=C1CCN(Cc2ccccc2)CC1(F)F -US20080096935A1,1,CC1(C2CCCC2)Cc2cc(O)c(Cl)c(Cl)c2C1=O.OCc1cccc(CSc2ccncc2)c1>>CC1(C2CCCC2)Cc2cc(OCc3cccc(CSc4ccncc4)c3)c(Cl)c(Cl)c2C1=O -US07109186B2,2,CC(=O)[O-].CNCc1ccc(Cl)c(Cl)c1>>CC(=O)N(C)Cc1ccc(Cl)c(Cl)c1 -US05516904,6,CC(C)CCC(C)(C)c1ccc(C#C[Si](C)(C)C)cc1>>C#Cc1ccc(C(C)(C)CCC(C)C)cc1 -US05183900,6,COC(=O)CC(CC(C)C)C(=O)OCc1ccccc1>>COC(=O)CC(CC(C)C)C(=O)O -US20080051586A1,1,CCOC(=O)CBr.Cc1[nH]c2cccc([N+](=O)[O-])c2c1Sc1ccc(Cl)cc1>>CCOC(=O)Cn1c(C)c(Sc2ccc(Cl)cc2)c2c([N+](=O)[O-])cccc21 -US08546359B2,7,CC(CCC(=O)O)(c1ccc2c(C(F)(F)F)c(O[C@@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1)[N+](=O)[O-]>>CC(N)(CCC(=O)O)c1ccc2c(C(F)(F)F)c(O[C@@H]3CC[C@@H](C(F)(F)F)CC3)ccc2c1 -US07053086B2,3,O=C1Cc2c(cccc2C2CCNCC2)N1.O=Cc1cc2ccccc2[nH]1>>O=C1Nc2cccc(C3CCNCC3)c2C1=Cc1cc2ccccc2[nH]1 -US20090062251A1,2,CCn1c2c(c3cc(C(=O)N(C)CCCC(=O)O)ccc31)CC(C1CCOCC1)CC2.NCC(F)(F)F>>CCn1c2c(c3cc(C(=O)N(C)CCCC(=O)NCC(F)(F)F)ccc31)CC(C1CCOCC1)CC2 -US20130245268A1,2,O=C(O)Cc1ccc([N+](=O)[O-])cc1C(=O)O>>O=C1Cc2ccc([N+](=O)[O-])cc2C(=O)O1 -US05643908,2,CC(C)[C@H]1COC(=O)N1.CCCCCCCCC(=O)Cl>>CCCCCCCCC(=O)N1C(=O)OC[C@@H]1C(C)C -US20150158879A1,2,CC(=O)OC(C)=O.CS(=O)(=O)c1nn(Cc2nc3cc(Cl)ccc3n2[C@@H]2CCNC2)c2cnccc12>>CC(=O)N1CC[C@@H](n2c(Cn3nc(S(C)(=O)=O)c4ccncc43)nc3cc(Cl)ccc32)C1 -US06518257B1,3,CC(C)[Mg+].COc1ccc(C=O)cc1-c1ccc(F)cc1>>COc1ccc(C(O)C(C)C)cc1-c1ccc(F)cc1 -US20100331326A1,1,CC1(C)CN(c2ccc3ncsc3c2)C(=O)N1.Cc1ccncc1I>>Cc1ccncc1N1C(=O)N(c2ccc3ncsc3c2)CC1(C)C -US20070173548A1,7,O=[N+]([O-])c1cc(Cl)c(Oc2ccc(O)c(S(=O)(=O)CC3CC3)c2)c(Cl)c1>>Nc1cc(Cl)c(Oc2ccc(O)c(S(=O)(=O)CC3CC3)c2)c(Cl)c1 -US08802684B2,6,CCC[C@H](C)Oc1nc(N)c2nc(OC)n(C3CCCCO3)c2n1>>CCC[C@H](C)Oc1nc(N)c2nc(OC)[nH]c2n1 -US08629147B2,7,CCN1CCC2(CCN(CCc3ccc([N+](=O)[O-])cc3)C2)C1>>CCN1CCC2(CCN(CCc3ccc(N)cc3)C2)C1 -US20110269741A1,3,CB(O)O.CCOC(=O)c1cn([C@H](CO[Si](C)(C)C(C)(C)C)C(C)C)c2nc(OC)c(Br)cc2c1=O>>CCOC(=O)c1cn([C@H](CO[Si](C)(C)C(C)(C)C)C(C)C)c2nc(OC)c(C)cc2c1=O -US20030018067A1,6,CCCCC(=O)c1c(-c2ccc3c(Cl)c(OCC(=O)OCC)ccc3c2)oc2ccccc12>>CCCCC(=O)c1c(-c2ccc3c(Cl)c(OCC(=O)O)ccc3c2)oc2ccccc12 -US20060235002A1,2,CCC(O)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)CC(O[Si](CC)(CC)CC)CCC(C)(O)C(OC(C)=O)C=CC1C.O=C(Cl)c1ccccc1>>CCC(OC(=O)c1ccccc1)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)CC(O[Si](CC)(CC)CC)CCC(C)(O)C(OC(C)=O)C=CC1C -US20070238734A1,2,NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CNCC2.O=C(Cl)Oc1ccccc1>>NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CN(C(=O)Oc1ccccc1)CC2 -US08530461B2,5,CCOc1ccc(OC2CN(c3ccc([C@H](C)N)cc3)C2)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOc1ccc(OC2CN(c3ccc([C@H](C)NC(=O)C(F)(F)F)cc3)C2)cc1 -US20150133424A1,2,COc1ccc(Cn2c(=O)c3c(Nc4cccc(C(=O)O)c4)c(C)c(=O)n(C)c3n(-c3ccc(I)cc3F)c2=O)cc1.OC1CCNC1>>COc1ccc(Cn2c(=O)c3c(Nc4cccc(C(=O)N5CCC(O)C5)c4)c(C)c(=O)n(C)c3n(-c3ccc(I)cc3F)c2=O)cc1 -US20100120798A1,7,CC(C)(C)OC(=O)N1CCC(C#N)(C(=O)Nc2ccc(F)cn2)CC1>>CC(C)(C)OC(=O)N1CCC(CN)(C(=O)Nc2ccc(F)cn2)CC1 -US05045228,1,CCCCCCCCCCCc1ccc(C(=O)O)c(C(=O)O)c1.O=C(OCc1ccccc1)c1ccc(O)cc1>>CCCCCCCCCCCc1ccc(C(=O)Oc2ccc(C(=O)OCc3ccccc3)cc2)c(C(=O)O)c1 -US20070037888A1,1,C1CCNC1.Cc1cc(Nc2cc(Cl)nc(N3CCCC3c3cc(-c4ccccn4)no3)n2)n[nH]1>>Cc1cc(Nc2cc(N3CCCC3)nc(N3CCCC3c3cc(-c4ccccn4)no3)n2)n[nH]1 -US20110021479A1,2,CC(=O)Cl.O=C(N[C@H]1CCCNC1)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>CC(=O)N1CCC[C@H](NC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C1 -US20150266857A1,6,CC(C)(C)OC(=O)N1CC2(CN(CCc3nc4ccc(-c5c[nH]c6cc(F)ccc56)cc4o3)C2)C1>>Fc1ccc2c(-c3ccc4nc(CCN5CC6(CNC6)C5)oc4c3)c[nH]c2c1 -US06541466B2,2,CC(C)COC(=O)[C@H](C)N.O=C(O)Cc1cc2ccccc2o1>>CC(C)COC(=O)[C@H](C)NC(=O)Cc1cc2ccccc2o1 -US20100298287A1,1,CCCC(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1c(C)cc(Cl)cc1Cl.CI>>CCCC(OC)c1ccc(Cl)c2nc3n(c12)CCCN3c1c(C)cc(Cl)cc1Cl -US20110190263A1,7,OCCCc1ccncc1>>OCCCC1CCNCC1 -US04621090,2,CNc1cccc(C)n1.S=C(Cl)Oc1ccc2ccccc2c1>>Cc1cccc(N(C)C(=S)Oc2ccc3ccccc3c2)n1 -US20140213581A1,6,COC(=O)c1nc2ccc(Cl)cn2c1C>>Cc1c(C(=O)O)nc2ccc(Cl)cn12 -US20110009390A1,10,COc1cccc([N+](=O)[O-])c1C.O=C1CCC(=O)N1Br>>COc1cccc([N+](=O)[O-])c1CBr -US08951964B2,6,CCOC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)c1cc(C)on1)C(=O)N1C[C@H](Oc3nc4cc(F)ccc4c4ccccc34)C[C@H]1C(=O)N2>>Cc1cc(C(=O)N[C@H]2CCCCCC=C[C@@H]3C[C@@]3(C(=O)O)NC(=O)[C@@H]3C[C@@H](Oc4nc5cc(F)ccc5c5ccccc45)CN3C2=O)no1 -US07309701B2,2,NCc1ccc(Cl)cc1Cl.O=C(O)c1cc(-c2cccnc2)n[nH]c1=O>>O=C(NCc1ccc(Cl)cc1Cl)c1cc(-c2cccnc2)n[nH]c1=O -US07531576B2,1,CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(CBr)cc1.CCCCCCCN>>CCCCCCCNCc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1 -US20090197880A1,1,Cc1cccc(C)c1-c1cc(CCl)on1.Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F>>Cc1cccc(C)c1-c1cc(Cn2cc3nc(-c4cccc(F)c4F)nc-3cn2)on1 -US04785004,3,CCCCCCCCCc1ccccc1Br.CN(C)C=O>>CCCCCCCCCc1ccccc1C=O -US20100130469A1,6,CC(C)(C)OC(=O)N1CCC(CNc2nc(-c3ccncc3)cc3cnccc23)CC1>>c1cc(-c2cc3cnccc3c(NCC3CCNCC3)n2)ccn1 -US20080275054A1,1,COc1ccc(-n2ncc3c(Cl)ncnc32)cc1.Nc1cccc(C(=O)Nc2cccc(C(F)(F)F)c2)c1>>COc1ccc(-n2ncc3c(Nc4cccc(C(=O)Nc5cccc(C(F)(F)F)c5)c4)ncnc32)cc1 -US20020006932A1,1,CC(C)N.Cc1ccccc1N1CN(CCO)C(=O)C12CCN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)CC2>>Cc1ccccc1N1CN(CCNC(C)C)C(=O)C12CCN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)CC2 -US20080085886A1,3,CC(C)(C)OC(=O)N1CCC(=O)C1.C[Mg+]>>CC1(O)CCN(C(=O)OC(C)(C)C)C1 -US20110136821A1,2,O=C(O)Cc1ccccc1C(F)(F)F.O=C1NC2(CCNCC2)c2c(Br)cccc21>>O=C1NC2(CCN(C(=O)Cc3ccccc3C(F)(F)F)CC2)c2c(Br)cccc21 -US08022075B2,8,CC(O)c1ccc(-c2cn3cc(I)ccc3n2)cc1>>CC(=O)c1ccc(-c2cn3cc(I)ccc3n2)cc1 -US07109190B2,1,Nc1nc(/C(=N/OC(c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N[C@H]2C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=C(Cl)CCC23)c(Cl)s1.Sc1nncs1>>Nc1nc(/C(=N/OC(c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N[C@H]2C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=C(Sc4nncs4)CCC23)c(Cl)s1 -US20150210697A1,6,COc1ccc(CN(c2nc(Nc3cc(C#N)c(CCCO)cc3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>N#Cc1cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c(Cl)cc1CCCO -US20100216766A1,7,CS(=O)(=O)c1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)cc1>>CS(=O)(=O)c1ccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)cc1 -US20080234199A1,3,CCOC(=O)COc1ccc(C(=O)CC)cc1.O=C(c1ccc(O)cc1)c1ccc(O)cc1>>CCOC(=O)COc1ccc(C(CC)=C(c2ccc(O)cc2)c2ccc(O)cc2)cc1 -US09133162B2,7,CC(C)(O)COc1ccc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2c1>>CC(C)(O)COc1ccc2c(Oc3ccc(N)cc3F)ccnc2c1 -US07294635B2,2,CCOC(=O)NS(=O)(=O)c1ccc(Cl)s1.CNc1cc2c(cc1F)C(=O)N(c1ccc(N)cc1)CC2>>CNc1cc2c(cc1F)C(=O)N(c1ccc(NC(=O)NS(=O)(=O)c3ccc(Cl)s3)cc1)CC2 -US20140357614A1,6,CC(C)CNc1nccc(N2CC[C@@H](NC(=O)OC(C)(C)C)C2)n1>>CC(C)CNc1nccc(N2CC[C@@H](N)C2)n1 -US06136969,6,CC(C)(C)OC(=O)N1CCC[C@@H](OC(=O)c2ccc(-c3ccccc3)cc2)[C@H](NC(=O)c2ccc(O[Si](C)(C)C(C)(C)C)cc2)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](OC(=O)c2ccc(-c3ccccc3)cc2)[C@H](NC(=O)c2ccc(O)cc2)C1 -US05808068,1,CC(=O)c1cc(N)cc(C(C)=O)c1.CSc1nccc(Cl)n1>>CSc1nccc(Nc2cc(C(C)=O)cc(C(C)=O)c2)n1 -US08536168B2,6,CCOC(=O)c1ccc(N2CCN(c3nnc(Cc4ccc(F)cc4)c4ccccc34)CC2)nc1>>O=C(O)c1ccc(N2CCN(c3nnc(Cc4ccc(F)cc4)c4ccccc34)CC2)nc1 -US20100331293A1,1,CCc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>CCc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1 -US04119710,7,N#Cc1cc(C(=O)CNC2CCC2)cc(Br)c1N>>N#Cc1cc(C(O)CNC2CCC2)cc(Br)c1N -US06071532,8,OCCCCCCCCCCO[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>O=CCCCCCCCCCO[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US20050234238A1,3,CC(=O)c1cccc(-c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c1.[Mg+]c1ccccc1>>CC(O)(c1ccccc1)c1cccc(-c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c1 -US20140128401A1,7,Cn1cc(-c2ccnc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2C=O)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O>>Cn1cc(-c2ccnc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2CO)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O -US20070208001A1,1,O=C(NC1CCCCC1)C1CCCC(O)C1.Oc1ccccc1Cl>>O=C(NC1CCCCC1)C1CCCC(Oc2ccccc2Cl)C1 -US20040247896A1,3,Brc1ccc(C#Cc2ccccc2)cc1.C#C[Si](C)(C)C>>C#Cc1ccc(C#Cc2ccccc2)cc1 -US20030013886A1,1,C(=Cc1nc2ccccc2[nH]1)c1ccccc1.Cc1ccnc(F)c1>>Cc1ccnc(-n2c(/C=C/c3ccccc3)nc3ccccc32)c1 -US05922734,7,CCOC(=O)c1ccc2ncccc2c1Cl>>OCc1ccc2ncccc2c1Cl -US20150166507A1,4,C#CCNC(=O)c1cccnc1Nc1ccc(Cl)cc1.[N-]=[N+]=NCc1cccc(Oc2ccccc2)c1>>O=C(NCc1cn(Cc2cccc(Oc3ccccc3)c2)nn1)c1cccnc1Nc1ccc(Cl)cc1 -US20140249139A1,3,COc1ccc(B(O)O)cn1.Cc1ccc(-c2ncnc3ccc(Br)cc23)cc1C(=O)O>>COc1ccc(-c2ccc3ncnc(-c4ccc(C)c(C(=O)O)c4)c3c2)cn1 -US20150011551A1,3,Brc1nccs1.CC1(C)OB(c2cncc(N)c2)OC1(C)C>>Nc1cncc(-c2nccs2)c1 -US05877317,2,CC(C(=O)O)c1ccccc1.O=C1N[C@@H](Cc2ccccc2)CO1>>CC(C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)c1ccccc1 -US20030148997A1,7,CC(=O)N[C@H]1[C@@H](OCc2ccccc2)O[C@H](COCc2ccccc2)[C@H](OC(=O)c2ccccc2)[C@@H]1OCc1ccccc1>>CC(=O)N[C@H]1[C@@H](OCc2ccccc2)O[C@H](COCc2ccccc2)[C@H](O)[C@@H]1OCc1ccccc1 -US06593322B1,2,COc1cccc(CCNc2ccccc2)c1.O=C(Cl)Cc1ccc(Br)cc1>>COc1cccc(CCN(C(=O)Cc2ccc(Br)cc2)c2ccccc2)c1 -US20040266840A1,3,O=Cc1c(Cl)cccc1Br.OB(O)c1ccncc1>>O=Cc1c(Cl)cccc1-c1ccncc1 -US20120208819A1,3,COC(=O)C[C@@H](NC(=O)OC(C)(C)C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Nc1ncnc2c1c(I)cn2S(=O)(=O)c1ccccc1>>COC(=O)C[C@@H](NC(=O)OC(C)(C)C)c1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1 -US08232287B2,2,CS(=O)(=O)c1ccc2c(c1)CCN2c1cc(OC2CCNCC2)ncn1.O=C(Cl)OCc1ccccc1>>CS(=O)(=O)c1ccc2c(c1)CCN2c1cc(OC2CCN(C(=O)OCc3ccccc3)CC2)ncn1 -US20070010537A1,7,CCOC(=O)Cc1cccc([N+](=O)[O-])c1C(=O)OC>>CCOC(=O)Cc1cccc(N)c1C(=O)OC -US05891909,8,Cc1cc(OCCCO)cc(OS(=O)(=O)c2ccccc2OC(F)(F)F)c1>>Cc1cc(OCCC=O)cc(OS(=O)(=O)c2ccccc2OC(F)(F)F)c1 -US20060247250A1,1,Cc1nc(Cl)cc(Cl)n1.OCCN1CCNCC1>>Cc1nc(Cl)cc(N2CCN(CCO)CC2)n1 -US20070254867A1,1,COC(=O)c1ccc(Cl)cc1I.Nc1ccc(Br)cc1[N+](=O)[O-]>>COC(=O)c1ccc(Cl)cc1Nc1ccc(Br)cc1[N+](=O)[O-] -US20080103123A1,2,C#CCOC(=O)Cl.CN(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCNCC1>>C#CCOC(=O)N1CCC(N(C)Cc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)CC1 -US20120322788A1,1,CC(C)c1csc(C(=O)N2CCOC3(CCNCC3)C2)n1.OCCc1cccc(CBr)c1>>CC(C)c1csc(C(=O)N2CCOC3(CCN(Cc4cccc(CCO)c4)CC3)C2)n1 -US08486967B2,1,CC(C)(O)c1cc(Cc2ccc(Cl)cc2)nc(Cl)n1.Cc1nnc(N2CCC(N)CC2)o1>>Cc1nnc(N2CCC(Nc3nc(Cc4ccc(Cl)cc4)cc(C(C)(C)O)n3)CC2)o1 -US05919806,2,CC(C)N=C=O.CC1(C)Oc2cc3nonc3cc2C(N)C1O>>CC(C)NC(=O)NC1c2cc3nonc3cc2OC(C)(C)C1O -US20080269220A1,1,FC(F)(F)c1ccc(Cl)nc1.O=C1CCc2c(O)cccc21>>O=C1CCc2c(Oc3ccc(C(F)(F)F)cn3)cccc21 -US20140163009A1,3,COC(=O)[C@H]1[C@H](c2ccc(Br)cc2)[C@H]1c1ccccc1.OB(O)c1cccc(OCc2ccccc2)c1>>COC(=O)[C@H]1[C@H](c2ccc(-c3cccc(OCc4ccccc4)c3)cc2)[C@H]1c1ccccc1 -US20050239789A1,1,CCOC(=O)c1cc2c(Br)cccc2[nH]1.N#CCCl>>CCOC(=O)c1cc2c(Br)cccc2n1CC#N -US04045433,2,O=C(Cl)Cl.O=C1CNC(c2ccccc2)c2cc(Cl)ccc2N1>>O=C1CN(C(=O)Cl)C(c2ccccc2)c2cc(Cl)ccc2N1 -US07208495B2,10,C=C1c2c(C)c(N3CCN(c4ccc(OC)cc4)CC3)c(C)c(C)c2OC1(C)C.O>>COc1ccc(N2CCN(c3c(C)c(C)c4c(c3C)C(CO)C(C)(C)O4)CC2)cc1 -US20130338367A1,1,CC(C)(C)OC(=O)Nc1cnn(C(C)(C)C)c1Cl.CCI>>CCN(C(=O)OC(C)(C)C)c1cnn(C(C)(C)C)c1Cl -US04843100,2,Nc1ccc(S(=O)C(F)(F)C(F)F)cc1F.O=C=NC(=O)c1c(F)cccc1Cl>>O=C(NC(=O)c1c(F)cccc1Cl)Nc1ccc(S(=O)C(F)(F)C(F)F)cc1F -US20100016396A1,3,CCOC(=O)CP(=O)(OCC)OCC.Cc1nn(C)c(Oc2cc(O)c(Cl)cc2Cl)c1C=O>>CCOC(=O)/C=C/c1c(C)nn(C)c1Oc1cc(O)c(Cl)cc1Cl -US08178522B2,2,CN.Cc1nc(CCc2c(-c3ccc(F)cn3)noc2C)sc1C(=O)O>>CNC(=O)c1sc(CCc2c(-c3ccc(F)cn3)noc2C)nc1C -US20080194549A1,2,CC(C)NC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1C(C)(C)O[SiH2]C(C)(C)C.COCCCOc1cc(C(=O)O)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C(C)(C)O[SiH2]C(C)(C)C)C(C)C)ccc1OC -US08604038B2,1,CC(=O)c1cccc(C)n1.[NH4+]>>Cc1cccc(C(C)N)n1 -US20040242572A1,2,CCCCc1ccc(C(=O)O)cc1.NCCc1ccc(CN2CCCC2)cc1>>CCCCc1ccc(C(=O)NCCc2ccc(CN3CCCC3)cc2)cc1 -US05723606,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1.O=C1CCCNc2ccccc21>>O=C1CCCN(C(=O)c2ccc([N+](=O)[O-])cc2)c2ccccc21 -US20120283260A1,2,CNC(=O)C1CN(CC(=O)O)CCO1.COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccc2n1Cc1ccccn1>>CNC(=O)C1CN(CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4Cc3ccccn3)c2Cl)CCO1 -US20060084690A1,8,CSc1ccc(-c2oncc2CCCO)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc(-c2oncc2CCCO)cc1 -US07470824B2,1,ClCCl.O=C1C2CC3CC(C2)C(O)C1C3>>O=C1C2CC3CC(C2)C(OCCl)C1C3 -US20080194535A1,2,C=CC[C@H](NC)C(=O)OC.O=S(=O)(Cl)CCC(F)(F)F>>C=CC[C@@H](C(=O)OC)N(C)S(=O)(=O)CCC(F)(F)F -US20070112003A1,1,C1CCNC1.Clc1ccc(-c2noc(-c3sccc3Cl)n2)cc1CBr>>Clc1ccc(-c2noc(-c3sccc3Cl)n2)cc1CN1CCCC1 -US05821261,7,CC(C)(C)OC(=O)[C@@H]1C[C@H](C#N)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@@H]1C[C@@H](CN)CN1C(=O)OC(C)(C)C -US08314138B2,2,Cc1nc(-c2ccn(CCN)n2)sc1C(=O)NCc1cccnc1.O=C(Cl)c1ccc(F)cc1>>Cc1nc(-c2ccn(CCNC(=O)c3ccc(F)cc3)n2)sc1C(=O)NCc1cccnc1 -US20150239866A1,4,C#Cc1cc(C)cc(Nc2cc(C(F)(F)F)ccn2)n1.COC(=O)C1(N)CC1.[N-]=[N+]=NS(=O)(=O)C(F)(F)F>>COC(=O)C1(n2cc(-c3cc(C)cc(Nc4cc(C(F)(F)F)ccn4)n3)nn2)CC1 -US20120316147A1,2,CCOC(=O)C(N)(CC)CC.O=C(O)c1ccc(Br)c(OCC2CC2)n1>>CCOC(=O)C(CC)(CC)NC(=O)c1ccc(Br)c(OCC2CC2)n1 -US20060116356A1,7,COc1c2c(c(OC(c3ccccc3)c3ccccc3)c3nccnc13)C(=O)N(Cc1ccc(F)cc1)C2=O>>COc1c2c(c(OC(c3ccccc3)c3ccccc3)c3nccnc13)C(=O)N(Cc1ccc(F)cc1)C2O -US20080004273A1,1,O=C(NCCCl)Nc1ccccn1>>O=C1NCCN1c1ccccn1 -US08829026B2,2,COC(=O)c1ccc(S(=O)(=O)Cl)cc1.NCc1cnc2ccccc2c1>>COC(=O)c1ccc(S(=O)(=O)NCc2cnc3ccccc3c2)cc1 -US20090099162A2,8,CN(C)C(=O)N(CCO)CCCc1ccc(C#N)cc1>>CN(C)C(=O)N(CC=O)CCCc1ccc(C#N)cc1 -US20140213586A1,2,CS(=O)(=O)Cl.O=C(c1c[nH]c2ccc(F)cc12)C(Cl)c1ccccc1>>CS(=O)(=O)n1cc(C(=O)C(Cl)c2ccccc2)c2cc(F)ccc21 -US20090239810A1,2,Clc1ccccc1OC1CNC1.O=C(O)CNC(=O)c1cn(-c2cccnc2)nn1>>O=C(NCC(=O)N1CC(Oc2ccccc2Cl)C1)c1cn(-c2cccnc2)nn1 -US20120225865A1,2,COC(=O)[C@@H]1CC[C@@H](Oc2cccc(C)n2)CC1.NN>>Cc1cccc(O[C@@H]2CC[C@@H](C(=O)NN)CC2)n1 -US20100216788A1,1,CC(C)(C)NC(=O)C1(c2cccc(O)c2)CC1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>CC(C)(C)NC(=O)C1(c2cccc(Oc3ccc([N+](=O)[O-])cc3Cl)c2)CC1 -US20120165309A1,1,CN[C@@H]1CC[C@@H](CNc2nc(N3CCOCC3)cc(-n3c(C(F)F)nc4ccccc43)n2)CC1.FCCBr>>CN(CCF)[C@@H]1CC[C@@H](CNc2nc(N3CCOCC3)cc(-n3c(C(F)F)nc4ccccc43)n2)CC1 -US04668673,1,BrCCCBr.Oc1cccc2c1OCCC2N1CCCCC1>>BrCCCOc1cccc2c1OCCC2N1CCCCC1 -US04738710,6,CCOC(=O)C(C)Oc1ccc(Nc2cnc3cc(Cl)ccc3c2)cc1>>CC(Oc1ccc(Nc2cnc3cc(Cl)ccc3c2)cc1)C(=O)O -US20040106653A1,1,CCOC(=O)CBr.O=S(=O)(c1ccc(CCCN(Cc2ccccc2)C[C@H](O)c2cccc(Cl)c2)cc1)c1cccc(O)c1>>CCOC(=O)COc1cccc(S(=O)(=O)c2ccc(CCCN(Cc3ccccc3)C[C@H](O)c3cccc(Cl)c3)cc2)c1 -US20110319378A1,1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](C=O)CC)C1=O.CC(C)(C)OC(=O)N1CCNCC1>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CN2CCN(C(=O)OC(C)(C)C)CC2)C1=O -US05955471,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1Cc2ccccc2CN1>>CCOC(=O)C1Cc2ccccc2CN1C(=O)OC(C)(C)C -US05624950,3,COc1ccccc1[C@H](C)C(=O)N1CC2C(=O)CCC(C)(C)C2C1.COc1ccccc1[Mg+]>>COc1ccccc1[C@H](C)C(=O)N1C[C@@H]2[C@H](C1)[C@@](O)(c1ccccc1OC)CCC2(C)C -US08252935B2,6,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C)N2)c1>>CC(C)CC(C(=O)O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C)N2)c1 -US20100204209A1,6,CN1CCOC(CN2CCN(Cc3ccccc3)CC2)C1>>CN1CCOC(CN2CCNCC2)C1 -US20120178736A1,3,Brc1ccc(OCc2ccccc2)c2nccn12.CCCC[Sn](CCCC)(CCCC)c1nc(N2CCOCC2)c2sc(CN3CCC(N(C)C)CC3)cc2n1>>CN(C)C1CCN(Cc2cc3nc(-c4ccc(OCc5ccccc5)c5nccn45)nc(N4CCOCC4)c3s2)CC1 -US20100256097A1,1,CC(=O)[O-].COC(=O)C(Br)c1cccc(Br)n1>>COC(=O)C(OC(C)=O)c1cccc(Br)n1 -US20080318947A1,1,CCN.O=[N+]([O-])c1cnc(Br)cc1Br>>CCNc1cc(Br)ncc1[N+](=O)[O-] -US09051311B2,3,COc1cc(C2CC2)ccc1B1OC(C)(C)C(C)(C)O1.O=S(=O)(Nc1ncns1)N1CCc2c(ccnc2Cl)C1>>COc1cc(C2CC2)ccc1-c1nccc2c1CCN(S(=O)(=O)Nc1ncns1)C2 -US20040204434A1,6,CCOC(=O)/C=C/C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)/C=C/C(=O)O -US20130060014A1,9,C=C(C)C[Si](CCCN=[N+]=[N-])(CC(=C)C)CC(=C)C>>C=C(C)C[Si](CCCN)(CC(=C)C)CC(=C)C -US05366987,4,CCOC(=O)CC#N.[N-]=[N+]=[N-]>>CCOC(=O)Cc1nnn[nH]1 -US07435744B2,1,Nc1ccc(NC(=O)C(=O)N2CCC(Cc3ccc(F)cc3)CC2)cc1.O=Cc1ccccc1>>O=C(Nc1ccc(NCc2ccccc2)cc1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1 -US08557805B2,2,C1COCCN1.CS(=O)(=O)c1ccc(Oc2cc(OC3CCOCC3)c3[nH]c(C4=NCC(CC(=O)O)S4)cc3c2)cn1>>CS(=O)(=O)c1ccc(Oc2cc(OC3CCOCC3)c3[nH]c(C4=NCC(CC(=O)N5CCOCC5)S4)cc3c2)cn1 -US20080287437A1,6,C[C@H](NC(=O)OC(C)(C)C)c1ncc(F)cc1F>>C[C@H](N)c1ncc(F)cc1F -US04319919,1,CC(C)(C)c1ccc(O)cc1.CCCCl>>CCCOc1ccc(C(C)(C)C)cc1 -US04575503,6,CCOC(=O)CN1C(=O)C(N=[N+]=[N-])CCc2ccc(OC)cc21>>COc1ccc2c(c1)N(CC(=O)O)C(=O)C(N=[N+]=[N-])CC2 -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCCC2=O)c1=O.C[C@@H](N)CC(=O)OC(C)(C)C>>C[C@H](CC(=O)OC(C)(C)C)NC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCCC2=O)c1=O -US05837708,1,COc1cccc(Cc2nc(Cl)c(Oc3ccccc3OC)c(NS(=O)(=O)c3ccc(C(C)C)cn3)n2)c1.OCCO>>COc1cccc(Cc2nc(NS(=O)(=O)c3ccc(C(C)C)cn3)c(Oc3ccccc3OC)c(OCCO)n2)c1 -US20150231135A1,9,CN1CCN(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4cccc(C(=O)OC(C)(C)C)c4)n3)cc2)CC1.[NH4+]>>CN1CCN(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4cccc(C(N)=O)c4)n3)cc2)CC1 -US20140228361A1,1,C#Cc1cc(N)ccc1F.COc1cc2ncnc(Cl)c2cc1OC(C)=O>>C#Cc1cc(Nc2ncnc3cc(OC)c(OC(C)=O)cc23)ccc1F -US04935440,1,CC(C)(C)c1cc(C(=O)c2c(Cl)[nH]c(Cl)c2Cl)cc(C(C)(C)C)c1O.CI>>Cn1c(Cl)c(Cl)c(C(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c1Cl -US20150080393A1,2,CC(C)O.Cc1ccn(-c2cc(-c3ccc(C)c(C)c3)ccc2[C@@H](Oc2cc(N3CCC4(CC3)CN[C@H](C(=O)O)C4)nc(N)n2)C(F)(F)F)n1>>Cc1ccn(-c2cc(-c3ccc(C)c(C)c3)ccc2[C@@H](Oc2cc(N3CCC4(CC3)CN[C@H](C(=O)OC(C)C)C4)nc(N)n2)C(F)(F)F)n1 -US20080058384A1,2,CC1=C(C(=O)O)C(c2ccc(C(F)(F)F)cc2F)CC(=O)N1.CCc1n[nH]c2ccc(N)cc12>>CCc1n[nH]c2ccc(NC(=O)C3=C(C)NC(=O)CC3c3ccc(C(F)(F)F)cc3F)cc12 -US20100256123A1,2,COc1cccc(C(=O)c2ccc3ccccc3c2N)c1.O=C(Br)CBr>>COc1cccc(C(=O)c2ccc3ccccc3c2NC(=O)CBr)c1 -US04438207,2,CCCCCc1cc(OCCCC(=O)O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21.NCCc1ccc(O)cc1>>CCCCCc1cc(OCCCC(=O)NCCc2ccc(O)cc2)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21 -US20030139416A1,1,Clc1ccc2c(c1)NCCC2.Clc1ncnc(Cl)n1>>Clc1ccc2c(c1)N(c1ncnc(Cl)n1)CCC2 -US07642267B2,1,CCCn1c(CCl)nc2cc(C#N)ccc21.Fc1cccc(-c2ncc[nH]2)n1>>CCCn1c(Cn2ccnc2-c2cccc(F)n2)nc2cc(C#N)ccc21 -US20110301122A1,9,Cc1cc(C(=O)O)nn1Cc1ccc(Cl)nc1.N>>Cc1cc(C(N)=O)nn1Cc1ccc(Cl)nc1 -US20080009518A1,3,O=S(=O)(OC1=CCCc2ncccc21)C(F)(F)F.OB(O)c1ccccc1>>C1=C(c2ccccc2)c2cccnc2CC1 -US08518972B2,2,COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(S(=O)(=O)N4CCOCC4)cc3)cccc2C1=O>>O=C1CCC(N2Cc3c(OCc4ccc(S(=O)(=O)N5CCOCC5)cc4)cccc3C2=O)C(=O)N1 -US06252086B1,3,C#CC1(O)CCNC1.CC(=O)c1c[nH]c(/C=C2\C(=O)Nc3ccc(F)c(I)c32)c1>>CC(=O)c1c[nH]c(/C=C2\C(=O)Nc3ccc(F)c(C#CC4(O)CCNC4)c32)c1 -US20130005707A1,7,Nc1ccc(I)cc1[N+](=O)[O-]>>Nc1ccc(I)cc1N -US05843975,2,CCOC(=O)Cl.Nc1noc2cc(OCc3ccccc3)ccc12>>CCOC(=O)Nc1noc2cc(OCc3ccccc3)ccc12 -US08691840B2,2,Nc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1.O=C(Cl)c1cccc(F)c1>>O=C(Nc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1)c1cccc(F)c1 -US20090054435A1,6,COc1ccc(C(=O)c2ccc(OCCc3ccccc3)nc2)c(OC(C)(C)C(=O)OC(C)(C)C)c1>>COc1ccc(C(=O)c2ccc(OCCc3ccccc3)nc2)c(OC(C)(C)C(=O)O)c1 -US05322847,1,C=[N+]=[N-].O=C(O)c1cccc(C[C@@H]2COc3ccc(OCc4nc5cc(F)ccc5s4)cc3[C@@H]2O)c1>>COC(=O)c1cccc(C[C@@H]2COc3ccc(OCc4nc5cc(F)ccc5s4)cc3[C@@H]2O)c1 -US04199525,3,CC[Mg+].O=Cc1ccccc1Br>>CCC(O)c1ccccc1Br -US06967198B2,2,CC1CC1C(=O)O.Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>CC1CC1C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O -US08778943B2,9,C[C@H](COS(C)(=O)=O)NC(=O)OC(C)(C)C.[C-]#N>>C[C@H](CC#N)NC(=O)OC(C)(C)C -US20130231336A1,3,COc1cccnc1Br.Fc1cc(-c2ccnc(Nc3ccc(-n4cnc(Br)n4)cc3)n2)cc(N2CCOCC2)c1>>COc1cccnc1-c1ncn(-c2ccc(Nc3nccc(-c4cc(F)cc(N5CCOCC5)c4)n3)cc2)n1 -US03996255,3,C#C[Mg+].CCCCCC(=O)C=CI>>C#CC(O)(C=CI)CCCCC -US20090264336A1,1,Cc1cnc(NC(=O)c2cc(O)cc(O[C@@H](C)CO[Si](C)(C)C(C)(C)C)c2)cn1.O=C(c1cnc(Cl)cn1)N1CCC1>>Cc1cnc(NC(=O)c2cc(Oc3cnc(C(=O)N4CCC4)cn3)cc(O[C@@H](C)CO[Si](C)(C)C(C)(C)C)c2)cn1 -US20110263584A1,3,C[C@@H](c1ccc(Br)cc1)N1CC[C@](CCO)(c2ccccc2)OC1=O.Cc1cc(B(O)O)ccn1>>Cc1cc(-c2ccc([C@H](C)N3CC[C@](CCO)(c4ccccc4)OC3=O)cc2)ccn1 -US06069156,1,CCC(=O)c1c(CC)[nH]c2cc(C(=O)OC)ccc12.Clc1ccccc1CBr>>CCC(=O)c1c(CC)n(Cc2ccccc2Cl)c2cc(C(=O)OC)ccc12 -US20140309192A1,6,COC(=O)c1ccc2c(c1)CN(C(=O)OC(C)(C)C)CC2>>CC(C)(C)OC(=O)N1CCc2ccc(C(=O)O)cc2C1 -US08268822B2,1,CCOC(=O)c1cccc(-c2ccnc(Cl)n2)c1.NCCc1ccc(O)cc1>>CCOC(=O)c1cccc(-c2ccnc(NCCc3ccc(O)cc3)n2)c1 -US20110071194A1,1,COc1cccc([C@@H](O)[C@H](C)N)c1.Clc1ccc(-n2ncc3cc(I)ccc32)cc1>>COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(Cl)cc3)c2)[C@H](C)N)c1 -US08722691B2,1,CC1(C)OB(c2ccc(-c3nc4c(-c5ccccc5)n[nH]c4c(=O)n3-c3ccc(Cl)cc3)cc2)OC1(C)C.CN(C)C(=O)Cl>>CN(C)C(=O)n1nc(-c2ccccc2)c2nc(-c3ccc(B4OC(C)(C)C(C)(C)O4)cc3)n(-c3ccc(Cl)cc3)c(=O)c21 -US20070093521A1,1,CCOc1cc(C=O)cc(OCC)c1-n1cccc1.COc1cccc2nc(NC3CCNCC3)oc12>>CCOc1cc(CN2CCC(Nc3nc4cccc(OC)c4o3)CC2)cc(OCC)c1-n1cccc1 -US20130261116A1,2,NC1CC1.O=C(O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1Cl>>O=C(NC1CC1)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1Cl -US08193203B2,1,CCN(CC)CCOc1cccc(N(C)C)c1C=O.COc1cc2nc(NCCN(C)C)nc(NC3CCNCC3)c2cc1OC>>CCN(CC)CCOc1cccc(N(C)C)c1CN1CCC(Nc2nc(NCCN(C)C)nc3cc(OC)c(OC)cc23)CC1 -US20150080373A1,2,CC(=O)Cl.O=C1CSc2ccc(C(=O)NC3CCN(CCOc4cnc5ccc(O)cc5n4)CC3)cc2N1>>CC(=O)Oc1ccc2ncc(OCCN3CCC(NC(=O)c4ccc5c(c4)NC(=O)CS5)CC3)nc2c1 -US04060528,10,Cc1cccc(C(=O)c2cccs2)c1Cl.O=C1CCC(=O)N1Br>>O=C(c1cccs1)c1cccc(CBr)c1Cl -US05847148,2,COC(=O)[C@H](CC(C)C)NC(=O)Nc1n[nH]c(=S)s1.NCc1ccccc1>>CC(C)C[C@H](NC(=O)Nc1n[nH]c(=S)s1)C(=O)NCc1ccccc1 -US09120749B2,3,CC1(C)OB(c2cc(F)c(O)c(Cl)c2)OC1(C)C.CCC(=O)c1cnc2ccc(Br)cc2c1N[C@@H]1CC[C@@H](CN(C)C)CC1>>CCC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1N[C@@H]1CC[C@@H](CN(C)C)CC1 -US20110263607A1,1,BrCCC(c1ccccc1)c1ccccc1.CCOC(CN)OCC>>CCOC(CNCCC(c1ccccc1)c1ccccc1)OCC -US06313307B1,6,CC(=O)NC[C@H]1CN(c2ccc(C3CN(C(=O)OCc4ccccc4)C3)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(C3CNC3)c(F)c2)C(=O)O1 -US04870074,6,COc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccccc2)CCO1>>COc1cc(N)c(Cl)cc1C(=O)NCC1CNCCO1 -US07662826B2,6,CC(C)(C)OC(=O)N1CCN(c2ccccc2CNC(=O)c2cnc3c(-c4cccc(Cl)c4)cnn3c2)CC1>>O=C(NCc1ccccc1N1CCNCC1)c1cnc2c(-c3cccc(Cl)c3)cnn2c1 -US20140163012A1,6,CC(C)(C)OC(=O)N1CCc2c(oc3cc(-n4ccc(-c5ccc(C(F)(F)F)nc5)cc4=O)ccc23)C1>>O=c1cc(-c2ccc(C(F)(F)F)nc2)ccn1-c1ccc2c3c(oc2c1)CNCC3 -US08969388B1,9,Cc1c(C(=O)Nc2ccc(Oc3ccnc(C(N)=O)c3Cl)c(F)c2)c(=O)n(-c2ccccc2)n1C>>Cc1c(C(=O)Nc2ccc(Oc3ccnc(N)c3Cl)c(F)c2)c(=O)n(-c2ccccc2)n1C -US20120098417A1,3,Cc1ccccc1-c1ncnc(Cl)c1C.OB(O)c1ccccc1>>Cc1ccccc1-c1ncnc(-c2ccccc2)c1C -US20110213149A1,7,NC(=CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F>>NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F -US08299267B2,6,CC(C)[Si](OCc1cncc(C(C)(C)F)c1)(C(C)C)C(C)C>>CC(C)(F)c1cncc(CO)c1 -US07994163B2,6,CC(C)CC(=O)CN1C(=O)c2ccccc2C1=O>>CC(C)CC(=O)CN -US07998959B2,6,O=C(NC1CCCCC1)C1CC2(CC2)CN1Cc1ccccc1>>O=C(NC1CCCCC1)C1CC2(CC2)CN1 -US20130317207A1,6,COc1ccc2c3c1CCCN3CCCC2>>Oc1ccc2c3c1CCCN3CCCC2 -US20090028925A1,7,COCOc1ccc(Cc2c(C)cc(C(=O)OC)cc2C)cc1Cc1ccc(F)cc1>>COCOc1ccc(Cc2c(C)cc(CO)cc2C)cc1Cc1ccc(F)cc1 -US08329726B2,7,O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4cccc(OCCCCl)c4)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(-c4cccc(OCCCCl)c4)sc23)c(F)c1 -US20110237578A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1.COC(=O)c1cc(Br)cc(I)c1>>COC(=O)c1cc(Br)cc(-c2ccc(C)cn2)c1 -US20120135421A1,6,CC(C)(C)NS(=O)(=O)c1cncc(-c2ccc3nc(NC(=O)NCCNC(=O)OC(C)(C)C)nn3c2)c1>>CC(C)(C)NS(=O)(=O)c1cncc(-c2ccc3nc(NC(=O)NCCN)nn3c2)c1 -US20100041892A1,2,CCCCOc1cc(C(=O)O)n(Cc2ccc(Cl)cc2Cl)n1.CNOC>>CCCCOc1cc(C(=O)N(C)OC)n(Cc2ccc(Cl)cc2Cl)n1 -US07863332B2,1,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1.COCCBr>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCCOC)c1 -US20090018103A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[Si](C)(C)CCOC(=O)NC[C@@H](N)CC1CCCCC1>>CC(C)(C)OC(=O)N[C@H](CNC(=O)OCC[Si](C)(C)C)CC1CCCCC1 -US05618839,3,CCCC[Sn](CCCC)(CCCC)c1ccccc1.COC(=O)c1ccc2c(c1)C(OS(=O)(=O)C(F)(F)F)=CC2(C)C>>COC(=O)c1ccc2c(c1)C(c1ccccc1)=CC2(C)C -US05030631,2,C1CNCCNC1.O=S(=O)(Cl)c1c2ccccc2cc2ccccc12>>O=S(=O)(c1c2ccccc2cc2ccccc12)N1CCCNCC1 -US20120270875A1,2,COC(=O)[C@H](CN)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C.O=C(O)c1sccc1Cl>>COC(=O)[C@H](CNC(=O)c1sccc1Cl)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C -US20080293743A1,6,COc1cc2c(cn1)CN(C(C)(C)C)CC2>>CC(C)(C)N1CCc2cc(O)ncc2C1 -US20110245237A1,1,BrCc1ccccn1.Clc1ccc2c(c1)CNCc1nnc([C@@H]3CC[C@@H](c4ccccc4)CC3)n1-2>>Clc1ccc2c(c1)CN(Cc1ccccn1)Cc1nnc([C@@H]3CC[C@@H](c4ccccc4)CC3)n1-2 -US20090274655A1,2,COC(=O)c1sc(-c2ccc(N)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C.O=C(O)c1cocn1>>COC(=O)c1sc(-c2ccc(NC(=O)c3cocn3)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C -US20140128401A1,7,Cc1cnc(Nc2cc(-c3ccnc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3C=O)cn(C)c2=O)s1>>Cc1cnc(Nc2cc(-c3ccnc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3CO)cn(C)c2=O)s1 -US20080039459A1,3,Cc1c(N)cccc1B1OC(C)(C)C(C)(C)O1.Clc1nc(N2CCOCC2)c2sccc2n1>>Cc1c(N)cccc1-c1nc(N2CCOCC2)c2sccc2n1 -US20100267712A1,7,O=C1c2cc([N+](=O)[O-])ccc2CN1c1ccc2ccsc2c1>>Nc1ccc2c(c1)C(=O)N(c1ccc3ccsc3c1)C2 -US05994368,7,Cc1cc(C=O)c2cccc(OCc3ccccc3)c2n1>>Cc1cc(CO)c2cccc(OCc3ccccc3)c2n1 -US04891358,2,O=C(O)CCCBr.OCC1c2ccccc2-c2ccccc21>>O=C(CCCBr)OCC1c2ccccc2-c2ccccc21 -US20100160388A1,1,COc1cc([N+](=O)[O-])ccc1I.C[S-]>>COc1cc([N+](=O)[O-])ccc1SC -US06933311B2,2,CCC(C(=O)O)c1cccc2cnccc12.NCc1ccc(C(F)(F)F)cc1>>CCC(C(=O)NCc1ccc(C(F)(F)F)cc1)c1cccc2cnccc12 -US20050096348A1,4,CC(=O)C(C)Br.CC(C)(C)OC(=O)NCCNC(N)=S>>Cc1nc(NCCNC(=O)OC(C)(C)C)sc1C -US07625908B2,2,C=CCNCCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12.CC(=O)Cl>>C=CCN(CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(C)=O -US07943607B2,6,CN(CCO[Si](C)(C)C(C)(C)C)C(=O)c1ccc(F)c(Cl)c1F>>CN(CCO)C(=O)c1ccc(F)c(Cl)c1F -US07923561B2,2,NCc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12.O=C(Cl)c1ccc(F)cc1>>O=C(NCc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12)c1ccc(F)cc1 -US07923573B2,3,COC(=O)Cc1ccc(OS(=O)(=O)C(F)(F)F)c(Cl)c1.COc1ccc(B(O)O)cc1>>COC(=O)Cc1ccc(-c2ccc(OC)cc2)c(Cl)c1 -US20140329804A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1ccc2nc3c(c(Cl)c2c1)CNCC3>>CC(C)(C)OC(=O)N1CCc2nc3ccc(C#N)cc3c(Cl)c2C1 -US20100317676A1,1,Clc1ncnc2c1CN(Cc1ccccc1)CC2.Nc1ccc(S(=O)(=O)C(F)(F)F)cc1>>O=S(=O)(c1ccc(Nc2ncnc3c2CN(Cc2ccccc2)CC3)cc1)C(F)(F)F -US20050113346A1,6,COC(=O)C1CN(Cc2ccccc2)CCCN1S(=O)(=O)c1ccc(OC)cc1>>COC(=O)C1CNCCCN1S(=O)(=O)c1ccc(OC)cc1 -US20080188521A1,2,C=CCC(O)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(F)(F)F.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>C=CCC(C#C[Si](C(C)C)(C(C)C)C(C)C)(OC(=O)c1ccc([N+](=O)[O-])cc1)C(F)(F)F -US20150166480A1,6,COC(=O)c1ccc(-c2ccc(N(Cc3ccccc3)CC3CCN(CC(C)(C)F)CC3)cc2)cc1>>COC(=O)c1ccc(-c2ccc(NCC3CCN(CC(C)(C)F)CC3)cc2)cc1 -US20120059002A1,6,COc1ccc2c(=O)[nH]c(-c3cc(C)c(OCCO[Si](C)(C)C(C)(C)C)c(C)c3)nc2c1>>COc1ccc2c(=O)[nH]c(-c3cc(C)c(OCCO)c(C)c3)nc2c1 -US20150224071A1,9,N#Cc1ccc(OCC23CC4CC(CC(C4)C2)C3)c(C2(O)CCC2)c1>>N#Cc1ccc(OCC23CC4CC(CC(C4)C2)C3)c(C2CCC2)c1 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1ccc2c(c1)OCCO2>>FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc5c(c4)OCCO5)c3)c(Cc3ccccc3)cnc12 -US04530922,1,C=CC[Si](c1ccc(F)cc1)(c1ccc(F)cc1)C(C)Cl.c1nc[nH]n1>>C=CC[Si](c1ccc(F)cc1)(c1ccc(F)cc1)C(C)n1cncn1 -US07425554B2,1,CC1(C)CC(c2ccccc2N2CCNCC2)CC1(C)C.CCC=O>>CCCN1CCN(c2ccccc2C2CC(C)(C)C(C)(C)C2)CC1 -US20060020133A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1>>N[C@@H]1CC[C@H](C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1 -US05219868,1,CCc1ccc(N=CN2CCNC2=N[N+](=O)[O-])cc1.ClCc1ccc(Cl)nc1>>CCc1ccc(N=CN2CCN(Cc3ccc(Cl)nc3)C2=N[N+](=O)[O-])cc1 -US09096600B2,3,C=CB1OB(C=C)OB(C=C)O1.COc1c(C(C)Nc2ncnc3c2ncn3C2CCCCO2)cc(Cl)c(F)c1Br>>C=Cc1c(F)c(Cl)cc(C(C)Nc2ncnc3c2ncn3C2CCCCO2)c1OC -US08110687B2,2,COc1ccc2c(c1)CC(C(=O)O)CC2.Nc1ccc(Cl)c(C(F)(F)F)c1>>COc1ccc2c(c1)CC(C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)CC2 -US20030208066A1,2,CC#CCOc1ccc(S(=O)(=O)Cl)cc1.CN>>CC#CCOc1ccc(S(=O)(=O)NC)cc1 -US08916557B2,1,CS(=O)(=O)Cc1cccc(Nc2ncnc(-c3ccc(F)cc3F)n2)c1.Cc1ccc(CO)cc1>>Cc1ccc(COc2cc(F)ccc2-c2ncnc(Nc3cccc(CS(C)(=O)=O)c3)n2)cc1 -US20040097498A1,2,CCCOc1ccc(N)cc1-c1nn2c(C3CCCC3)nc(C)c2c(=O)[nH]1.CN1CCN(S(=O)(=O)Cl)CC1>>CCCOc1ccc(NS(=O)(=O)N2CCN(C)CC2)cc1-c1nn2c(C3CCCC3)nc(C)c2c(=O)[nH]1 -US20070207175A1,6,CCCCOc1cc(CCC(=O)OC)ccc1-c1cccc(CN(C)C(=O)c2cccc(OC)c2)c1>>CCCCOc1cc(CCC(=O)O)ccc1-c1cccc(CN(C)C(=O)c2cccc(OC)c2)c1 -US20140357642A1,3,Clc1nc2cccnc2nc1Cl.OB(O)c1ccccc1>>Clc1nc2cccnc2nc1-c1ccccc1 -US20110207716A1,1,CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C(C)C.Clc1cc(Cl)cc(-c2ncc[nH]2)c1>>CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3cc(Cl)cc(Cl)c3)nc2N1C(C)C -US20140275508A1,9,C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)Cn1cnc2c(Cl)ncnc21.N>>C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)Cn1cnc2c(N)ncnc21 -US20100210633A1,6,CC(C)(C)OC(=O)N1CCC(C)(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1>>CC1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCNCC1 -US04954502,9,BrC(Br)(Br)Br.Cn1cc(CCO)c2ccccc21>>Cn1cc(CCBr)c2ccccc21 -US20070142377A1,2,O=C(C=Cc1cccnc1)NCCCCC1CCNCC1.O=S(=O)(O)c1ccc2ccccc2c1>>O=C(C=Cc1cccnc1)NCCCCC1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1 -US04099000,2,CC(=O)OCC1(O)CS[C@@H]2[C@@H](N=[N+]=[N-])C(=O)N2C1C(=O)OCc1ccc([N+](=O)[O-])cc1.CS(=O)(=O)Cl>>CC(=O)OCC1(OS(C)(=O)=O)CS[C@@H]2[C@@H](N=[N+]=[N-])C(=O)N2C1C(=O)OCc1ccc([N+](=O)[O-])cc1 -US20070010556A1,6,CC(C)(C)OC(=O)N1CCC[C@H](NC(=O)c2sc(-c3ccc(Cl)cc3)cc2NC(N)=O)C1>>NC(=O)Nc1cc(-c2ccc(Cl)cc2)sc1C(=O)N[C@H]1CCCNC1 -US20100273767A1,1,BrCc1ccccc1.O=[N+]([O-])c1ccc(O)cc1F>>O=[N+]([O-])c1ccc(OCc2ccccc2)cc1F -US04923891,1,CCCc1c(OCCCBr)ccc(C(C)=O)c1O.CCOC(=O)CCC1(CCC(=O)OCC)OC(CS)CS1>>CCCc1c(OCCCSCC2CSC(CCC(=O)OCC)(CCC(=O)OCC)O2)ccc(C(C)=O)c1O -US07192982B2,6,CCOC(=O)[C@H](Cc1ccc(OCCCOc2ccc(OCC(F)(F)C(F)F)cc2)cc1)OC>>CO[C@@H](Cc1ccc(OCCCOc2ccc(OCC(F)(F)C(F)F)cc2)cc1)C(=O)O -US20040138223A1,2,COc1ccc(NCc2ccc(N(C)C)cc2)cn1.O=C(O)C1CCCc2c(OCc3ccccc3)cccc21>>COc1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1 -US20090186902A1,2,Cc1cc(C2CCc3nc(C(=O)O)cn3C2)ccc1F.c1ccc(CC2CCNCC2)cc1>>Cc1cc(C2CCc3nc(C(=O)N4CCC(Cc5ccccc5)CC4)cn3C2)ccc1F -US20060041128A1,1,CC(C)=O.CCC(c1nc2snc(C)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1>>CCC(c1nc2snc(C)c2c(=O)n1Cc1ccccc1)N(CCCNC(C)C)C(=O)c1ccc(C)cc1 -US20100105732A1,1,CC(C)c1noc(N2CCC(CCCO)CC2)n1.CCOC(=O)c1ccc(O)nc1C>>CCOC(=O)c1ccc(OCCCC2CCN(c3nc(C(C)C)no3)CC2)nc1C -US20140073620A1,6,CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)nc2)ncc1Cl>>CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(C3CCNCC3)nc2)ncc1Cl -US20040110945A1,6,COC(=O)Cc1ccc2nc(Nc3cccc(F)c3C)oc2c1F>>Cc1c(F)cccc1Nc1nc2ccc(CC(=O)O)c(F)c2o1 -US20120289522A1,1,BrCc1ccccn1.CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CCO)cc3)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CCOCc4ccccn4)cc3)cc2)CC1 -US20050245593A1,4,CCOC(=O)CCC(C)=O.NNc1ccc(F)cc1>>CCOC(=O)Cc1c(C)[nH]c2ccc(F)cc12 -US08748412B2,6,CCOC(=O)C(Cc1ccc(-c2noc(-c3ccc(NC(=O)OC(C)(C)C)cc3)n2)c(F)c1)NS(=O)(=O)N1CCN(Cc2ccc(C)cc2)CC1>>Cc1ccc(CN2CCN(S(=O)(=O)NC(Cc3ccc(-c4noc(-c5ccc(NC(=O)OC(C)(C)C)cc5)n4)c(F)c3)C(=O)O)CC2)cc1 -US20130096160A1,1,Brc1csc(Br)n1.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(c2nc(Br)cs2)CC1 -US20090029981A1,3,C#CCO[C@@H]1CNC[C@H](OC(c2ccc3c(c2)N(CCCOC)CCO3)S(=O)(=O)c2ccc(C)cc2)[C@@H]1c1ccc(OC)cc1.C1COCCN1.C=O>>COCCCN1CCOc2ccc(C(O[C@H]3CNC[C@@H](OCC#CCN4CCOCC4)[C@H]3c3ccc(OC)cc3)S(=O)(=O)c3ccc(C)cc3)cc21 -US20090069328A1,2,CC(C)Oc1ccc(C#Cc2ccccc2)cc1C(=O)O.COC(=O)C(C)(N)Cc1c[nH]c2ccccc12>>COC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)c1cc(C#Cc2ccccc2)ccc1OC(C)C -US04222767,6,COc1ccc2c(c1)C(C)(C)CO2>>CC1(C)COc2ccc(O)cc21 -US20090253677A1,3,CC(C)(C)[Si](C)(C)OCC1CCC(C=O)C1.CN.[C-]#N>>CNC(C#N)C1CCC(CO[Si](C)(C)C(C)(C)C)C1 -US20090137609A1,6,CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)c(Cl)c2)c(C)c1>>CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)O)c(Cl)c2)c(C)c1 -US04453965,2,CC(C)Nc1ccc(F)cc1.O=C(Cl)CCl>>CC(C)N(C(=O)CCl)c1ccc(F)cc1 -US04233333,2,CC(C)(C)N.CCc1ccc(S(=O)(=O)O)o1>>CCc1ccc(S(=O)(=O)NC(C)(C)C)o1 -US07223793B2,2,COC(=O)[C@@H](N)CCSC.O=C(O)CCc1ccc(O)cc1>>COC(=O)C(CCSC)NC(=O)CCc1ccc(O)cc1 -US20080261951A1,10,COC(=O)c1ccc(C)c(Cl)c1.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(CBr)c(Cl)c1 -US20140288123A1,6,COC(=O)c1ccc(C(C)n2ccccc2=O)cc1>>CC(c1ccc(C(=O)O)cc1)n1ccccc1=O -US06365588B1,1,C=O.O=C(O)CC1CCNCC1>>CN1CCC(CC(=O)O)CC1 -US07655641B2,2,CCCNCCSc1ccc(OCC(=O)OCC)c(C)c1.Cc1c(S(=O)(=O)Cl)sc2ccc(C(F)(F)F)cc12>>CCCN(CCSc1ccc(OCC(=O)OCC)c(C)c1)S(=O)(=O)c1sc2ccc(C(F)(F)F)cc2c1C -US20050090472A1,2,CC(C)COc1ccc(C(=O)O)cc1C#N.COC(=O)c1cccc(N)c1Cl>>COC(=O)c1cccc(NC(=O)c2ccc(OCC(C)C)c(C#N)c2)c1Cl -US20150166549A1,3,CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(I)c2c(N)ncnc21.C[Sn](C)(C)c1cccc2[nH]ncc12>>CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(-c2cccc3[nH]ncc23)c2c(N)ncnc21 -US20040147586A1,3,O=C1Cc2cc(-c3ccccc3)ccc2N1.O=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1>>O=C1Nc2ccc(-c3ccccc3)cc2C1=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1 -US04625034,7,O=C(O)C1CCc2ccccc2C1>>OCC1CCc2ccccc2C1 -US20150225342A1,3,CC(C)(C)OC(=O)N1CC(=O)C1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1CN(C(=O)OC(C)(C)C)C1 -US20060293344A1,1,COCCN.COc1ccc(-c2nn3c(Cl)cccc3c2-c2ccnc(NC3CCCC3)n2)cc1>>COCCNc1cccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(OC)cc3)nn12 -US08980889B2,1,C[C@H]1CCCN1.Cn1ncc(-c2nc(C(F)F)cs2)c1C(=O)Nc1ccn2nc(Br)nc2c1>>C[C@H]1CCCN1c1nc2cc(NC(=O)c3c(-c4nc(C(F)F)cs4)cnn3C)ccn2n1 -US04271160,7,COc1ccccc1OC(c1ccccc1)C(O)C[N+](=O)[O-]>>COc1ccccc1OC(c1ccccc1)C(O)CN -US04639266,6,COC(=O)c1nc(C(Cl)(Cl)Cl)n(-c2cccc(C(F)(F)F)c2)n1>>O=C(O)c1nc(C(Cl)(Cl)Cl)n(-c2cccc(C(F)(F)F)c2)n1 -US20070049632A1,1,CC1(C)[C@H]2CC[C@]1(C)c1[nH]n(-c3ccccc3Cl)c(=O)c12.CCI>>CCn1c2c(c(=O)n1-c1ccccc1Cl)[C@@H]1CC[C@@]2(C)C1(C)C -US20130303538A1,2,CCCCCCCCC(=O)O.COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1>>CCCCCCCCC(=O)O[C@@]1(C#Cc2cccc(C)c2)CCC[C@@H]2[C@H]1CCN2C(=O)OC -US20100168105A1,1,CCOC(=O)C1CC12CCNCC2.O=C1CCOCC1>>CCOC(=O)C1CC12CCN(C1CCOCC1)CC2 -US20030176454A1,1,Cc1ncn(-c2cccc(N)c2)c1C.Clc1cc(-c2cccs2)ncn1>>Cc1ncn(-c2cccc(Nc3cc(-c4cccs4)ncn3)c2)c1C -US04954516,1,CCNCC.O=C1CC(CCl)CN1Cc1ccccc1>>CCN(CC)CC1CC(=O)N(Cc2ccccc2)C1 -US08822471B2,1,Cc1cnc(Cl)cn1.O=C(c1ccc(-c2cnco2)cc1)N(C1CCNCC1)C1CC1>>Cc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)cc3)C3CC3)CC2)cn1 -US08354444B2,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.NC(=O)c1sccc1N>>CC(C)(C)CC1NC(C(=O)Nc2ccsc2C(N)=O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F -US20140249132A1,6,COc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C)c1C1CN(C(=O)OC(C)(C)C)C1>>COc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C)c1C1CNC1 -US07749530B2,7,O=C1Cc2cc(C(=O)c3cccc([N+](=O)[O-])c3)ccc2N1>>Nc1cccc(C(=O)c2ccc3c(c2)CC(=O)N3)c1 -US08877757B2,2,COCCCN.COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(C(=O)O)cc2)cc(OC)c1>>COCCCNC(=O)c1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Nc2cc(OC)cc(OC)c2)cc1 -US20080312226A1,2,Nc1nc[nH]n1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1nc[nH]n1)OCC(Cl)(Cl)Cl -US08883786B2,6,COc1ccc(C(C)C(O)(c2cnc(C)cn2)C(F)(F)F)c(Cl)c1>>Cc1cnc(C(O)(C(C)c2ccc(O)cc2Cl)C(F)(F)F)cn1 -US05207947,1,CCCCCCCCC(CF)OC(=O)c1ccc(O)cc1.CCCCCCCCOc1ccc(C(=O)O)cc1>>CCCCCCCCOc1ccc(C(=O)Oc2ccc(C(=O)OC(CF)CCCCCCCC)cc2)cc1 -US20110117125A1,2,CN(C)CC(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1.CS(=O)(=O)Cl>>CN(C)CC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)OS(C)(=O)=O -US07981883B2,6,CCOC(=O)C1CCC2(CC1)CC(C)=NO2>>CC1=NOC2(CCC(C(=O)O)CC2)C1 -US20040266839A1,2,Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)O)cc3)c2)o1.NCc1ccccc1Cl>>Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCc4ccccc4Cl)cc3)c2)o1 -US20130216498A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(OCCN3CCCC3)nc(-c3cnc4ccc(F)cn34)n2)C1>>Fc1ccc2ncc(-c3nc(N[C@@H]4CCCNC4)cc(OCCN4CCCC4)n3)n2c1 -US04146546,2,CC(O)C(CO)C(C)O.CCCCCCCCCCCCCCCCNc1ccc(C(=O)Cl)cc1>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)OC(C)C(CO)C(C)O)cc1 -US20120115851A1,2,COC(=O)c1cc(OCCCN2CCCCC2)ccc1N.O=C(O)c1cccc(CCl)c1>>COC(=O)c1cc(OCCCN2CCCCC2)ccc1NC(=O)c1cccc(CCl)c1 -US06248919B1,3,COC(=O)c1ccc(C(=O)OC)c(I)c1.Cc1ccccc1B(O)O>>COC(=O)c1ccc(C(=O)OC)c(-c2ccccc2C)c1 -US20090082434A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1ccccc1C(F)(F)F>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4ccccc4C(F)(F)F)c3O2)cc1 -US05206235,3,CC(=O)c1ccccc1Br.Cc1ccc([Sn](C)(C)C)cc1>>CC(=O)c1ccccc1-c1ccc(C)cc1 -US08981084B2,1,CC1CNCCN1.N#Cc1ccc(Cl)nc1>>CC1CN(c2ccc(C#N)cn2)CCN1 -US20140179662A1,1,COC[C@H]1CCN1.NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1>>COC[C@H]1CCN1c1ncnc(Nc2cccc(CS(N)(=O)=O)c2)n1 -US20100144755A1,6,Cc1ccc(C(=O)NCC2CC2)cc1-c1nc(NC2CCN(C(=O)OC(C)(C)C)CC2)nc2c1ccc(=O)n2-c1c(F)cccc1F>>Cc1ccc(C(=O)NCC2CC2)cc1-c1nc(NC2CCNCC2)nc2c1ccc(=O)n2-c1c(F)cccc1F -US20140073700A1,9,COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)[C@](O)(C(=O)C=C4[C@@]5(C)C=C(I)C(=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1.N#C[Cu]>>COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)[C@](O)(C(=O)C=C4[C@@]5(C)C=C(C#N)C(=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1 -US20040097420A1,2,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O.CNOC>>CON(C)C(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C -US20140315191A1,3,C#CCNC(=O)C(F)(F)F.C=CCO[C@H]1C[C@H](n2cc(I)c(N)nc2=O)O[C@@H]1CO>>C=CCO[C@H]1C[C@H](n2cc(C#CCNC(=O)C(F)(F)F)c(N)nc2=O)O[C@@H]1CO -US20100144733A1,1,CI.Oc1c(Br)cccc1Br>>COc1c(Br)cccc1Br -US20070142372A1,7,CCNC(=O)c1ccc(C)c(-c2ccc3c(C4=CCNCC4)n[nH]c3c2)c1>>CCNC(=O)c1ccc(C)c(-c2ccc3c(C4CCNCC4)n[nH]c3c2)c1 -US20130324501A1,7,O=C(O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1)c1cccn1S(=O)(=O)c1ccc([N+](=O)[O-])cc1>>Nc1ccc(S(=O)(=O)n2cccc2C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1 -US04051254,2,CCCS(=O)(=O)Cl.CNC(=O)Oc1cc(C)c(N)c(C)c1>>CCCS(=O)(=O)Nc1c(C)cc(OC(=O)NC)cc1C -US20100234433A1,1,CI.Cc1cc(CO)cc(C)c1[N+](=O)[O-]>>COCc1cc(C)c([N+](=O)[O-])c(C)c1 -US20110152257A1,3,C#Cc1cnc2cc(C(C)(C)C)nn2c1.Clc1ccc(I)cn1>>CC(C)(C)c1cc2ncc(C#Cc3ccc(Cl)nc3)cn2n1 -US20100113465A1,3,CC1CN(C(=O)OC(C)(C)C)CCC1=O.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1CCN(C(=O)OC(C)(C)C)CC1C -US06156758,6,COC(=O)c1ccc(NC2CCN(c3nc(N)c4cc(OC)c(OC)cc4n3)CC2)nc1>>COc1cc2nc(N3CCC(Nc4ccc(C(=O)O)cn4)CC3)nc(N)c2cc1OC -US20150087646A1,2,COc1ccc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)cc1C(=O)O.NCC1CC1>>COc1ccc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)cc1C(=O)NCC1CC1 -US20140112945A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1cc(C[C@@H](N)C(=O)O)c2ccccc21>>Cn1cc(C[C@@H](NC(=O)OC(C)(C)C)C(=O)O)c2ccccc21 -US07326716B2,7,CCOC(=O)COCCCCN1C(=O)CCC[C@@H]1/C=C/C(=O)Cc1cccc(Cl)c1>>CCOC(=O)COCCCCN1C(=O)CCC[C@@H]1/C=C/C(O)Cc1cccc(Cl)c1 -US03963780,1,NCCc1ccccc1.O=[N+]([O-])c1ccc(Cl)cc1>>O=[N+]([O-])c1ccc(NCCc2ccccc2)cc1 -US04081452,1,CNO.ClCc1nnc2n1-c1ccc(Br)cc1C(c1ccccn1)=NC2>>CN(O)Cc1nnc2n1-c1ccc(Br)cc1C(c1ccccn1)=NC2 -US20110237565A1,3,CC(C)(C)OC(=O)N1CCN(c2ncc(Br)n3cnnc23)CC1.CC(C)C[Zn+]>>CC(C)Cc1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)c2nncn12 -US04246268,7,O=C(CCCN1CCC(Cc2ccc(Cl)c3ccccc23)CC1)c1ccccc1>>OC(CCCN1CCC(Cc2ccc(Cl)c3ccccc23)CC1)c1ccccc1 -US20150210689A1,3,CB1OB(C)OB(C)O1.COC(=O)c1cc(C(F)(F)F)cc(I)c1N>>COC(=O)c1cc(C(F)(F)F)cc(C)c1N -US07947706B2,2,COc1cc(N=C=O)cc(OC)c1.NC(=O)c1[nH]c2cnccc2c1-c1ccc(N)cc1>>COc1cc(NC(=O)Nc2ccc(-c3c(C(N)=O)[nH]c4cnccc34)cc2)cc(OC)c1 -US03941821,6,CCOC(=O)C(O)c1ccc(-c2ccccc2Cl)cc1>>O=C(O)C(O)c1ccc(-c2ccccc2Cl)cc1 -US20100094000A1,3,CC1(C)OB(c2ccc3c(c2)NC(=O)CO3)OC1(C)C.COc1ccc(Cn2nc(C)c(Br)c2-c2ccc(F)cc2)cn1>>COc1ccc(Cn2nc(C)c(-c3ccc4c(c3)NC(=O)CO4)c2-c2ccc(F)cc2)cn1 -US20150080412A1,2,CS(=O)(=O)Cl.OCc1ccc(C2(O)COC2)cc1>>CS(=O)(=O)OCc1ccc(C2(O)COC2)cc1 -US08481524B2,3,Cc1ccsc1Br.OB(O)c1ccncc1>>Cc1ccsc1-c1ccncc1 -US20130303524A1,1,C#CC(C)(C)Cl.c1ccc2c(c1)[nH]c1ccccc12>>C#CC(C)(C)n1c2ccccc2c2ccccc21 -US20080032998A1,2,CC1CC(c2ccco2)=CCN1.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1CC(c2ccco2)=CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US04011229,6,Cc1cnc2c(c1)CCCC2NC(=S)NC(=O)c1ccccc1>>Cc1cnc2c(c1)CCCC2NC(N)=S -US20130109701A1,1,N#Cc1cc(Br)ccc1CBr.Oc1ccc(Cl)c(Cl)c1>>N#Cc1cc(Br)ccc1COc1ccc(Cl)c(Cl)c1 -US08124629B2,7,O=Cc1ccc(SCc2ccccc2)cc1>>OCc1ccc(SCc2ccccc2)cc1 -US20060160864A1,2,CCCCOCCOc1ccc(-c2ccc(N(C)CCOC)c(/C=C/C(=O)O)c2)cc1.CCCn1cncc1C[S@](=O)c1ccc(N)cc1>>CCCCOCCOc1ccc(-c2ccc(N(C)CCOC)c(/C=C/C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1 -US08324245B2,9,COc1cc2nccc(Oc3ccc(N)cc3Cl)c2cc1OC>>COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC -US07572808B2,9,N#Cc1ccc(-c2ccnc(Cl)c2Br)cc1.NN>>N#Cc1ccc(-c2ccnc(NN)c2Br)cc1 -US07635715B2,6,C[C@@H](NC(=O)C1=C(O)c2cc(Cl)ccc2C2(CCOCC2)C1=O)C(=O)OC(C)(C)C>>C[C@@H](NC(=O)C1=C(O)c2cc(Cl)ccc2C2(CCOCC2)C1=O)C(=O)O -US07211572B2,2,CC(=O)Cl.CC(C)CNc1cn2ccn(Cc3cccc(Cl)c3)c(=O)c2c(O)c1=O>>CC(=O)N(CC(C)C)c1cn2ccn(Cc3cccc(Cl)c3)c(=O)c2c(O)c1=O -US07332499B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]([NH3+])c1ccc(Br)cc1F>>C[C@@H](NC(=O)OC(C)(C)C)c1ccc(Br)cc1F -US20090247617A1,2,CC(C)(C)O.O=C=NS(=O)(=O)Cl>>CC(C)(C)OC(=O)NS(=O)(=O)Cl -US07247633B2,1,Clc1cncc(Cl)n1.OC1CCCc2ccccc21>>Clc1cncc(OC2CCCc3ccccc32)n1 -US20090227575A1,1,CN(C)CCCl.Clc1nc(N2CCOCC2)c2ccc3[nH]ccc3c2n1>>CN(C)CCn1ccc2c3nc(Cl)nc(N4CCOCC4)c3ccc21 -US07622508B2,1,Fc1cccc(F)c1CBr.NCCO>>OCCNCc1c(F)cccc1F -US07786307B2,6,CCOC(=O)C(C)(C)n1ccnc1>>CC(C)(C(=O)O)n1ccnc1 -US20110212968A1,1,CC(C)(C)OC(=O)NCCBr.CCc1nc(I)c(I)[nH]1>>CCc1nc(I)c(I)n1CCNC(=O)OC(C)(C)C -US08569535B2,2,CCOC(=O)C1(N)Cc2ccccc2C1.O=C(O)c1cccc2c1CCCC2=O>>CCOC(=O)C1(NC(=O)c2cccc3c2CCCC3=O)Cc2ccccc2C1 -US06015817,6,CC(C)(C)OC(=O)N1CCc2sc(-c3ccccc3)cc2C1>>c1ccc(-c2cc3c(s2)CCNC3)cc1 -US06124287,1,CC(C)N.Clc1nc2ccccc2n2ccnc12>>CC(C)Nc1nc2ccccc2n2ccnc12 -US20140148416A1,3,Cc1ccc(B(O)O)cc1.O=[N+]([O-])c1ccc(Cl)nc1>>Cc1ccc(-c2ccc([N+](=O)[O-])cn2)cc1 -US08907091B2,7,O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4ccc(C5OCCO5)cn4)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(-c4ccc(C5OCCO5)cn4)sc23)c(F)c1 -US20070142371A1,4,C#Cc1ccc(NC2CC2)nc1.COc1c(NC(=O)c2ccc(C)c(N=[N+]=[N-])c2)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)c2ccc(C)c(-n3cc(-c4ccc(NC5CC5)nc4)nn3)c2)cc(C(C)(C)C)cc1NS(C)(=O)=O -US08299267B2,3,COC(=O)c1cc(Br)cc(C(=O)OC)c1.OB(O)c1cccc(Cl)c1>>COC(=O)c1cc(C(=O)OC)cc(-c2cccc(Cl)c2)c1 -US07074800B1,6,COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCC1CCN(C(=O)OC(C)(C)C)CC1>>COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCC1CCNCC1 -US08367681B2,3,O=C(O)c1ccc(B(O)O)s1.O=Cc1cnn2ccc(Cl)nc12>>O=Cc1cnn2ccc(-c3ccc(C(=O)O)s3)nc12 -US20110076291A1,1,CC(C)n1cnnc1-c1nc2c(s1)CCOc1cc(C=O)ccc1-2.NCCO>>CC(C)n1cnnc1-c1nc2c(s1)CCOc1cc(CNCCO)ccc1-2 -US20150099748A1,4,CCOC(=O)C(=O)CC(=O)c1cnc(Oc2ccccc2)nc1.NN>>CCOC(=O)c1cc(-c2cnc(Oc3ccccc3)nc2)[nH]n1 -US06867218B2,7,CCOC(=O)/C=C(\C)c1ccc(-c2ccco2)cc1>>C/C(=C\CO)c1ccc(-c2ccco2)cc1 -US20150011564A1,1,COc1ccc(N2CCNCC2)cc1C(F)(F)F.COc1ccc(NC(=O)CBr)c([N+](=O)[O-])c1>>COc1ccc(NC(=O)CN2CCN(c3ccc(OC)c(C(F)(F)F)c3)CC2)c([N+](=O)[O-])c1 -US20130216498A1,1,C[C@H](N)c1ccccc1.Clc1ccnc(Cl)n1>>C[C@H](Nc1ccnc(Cl)n1)c1ccccc1 -US20050070515A1,1,ICCCI.O=C1OCCC1S>>O=C1OCCC1SCCCI -US08207370B2,7,CCCCCCCCCCCCCCCCCC(=O)NC(C(=O)CCCCCCCCCCCCCCC)C(=O)OCC>>CCCCCCCCCCCCCCCCCC(=O)N[C@@H](C(=O)OCC)[C@H](O)CCCCCCCCCCCCCCC -US20090209422A1,1,CCOC(=O)C(C)=O.Cc1cccc(N)c1C>>CCOC(=O)C(C)Nc1cccc(C)c1C -US08962674B2,2,CC(C)(C)OC(=O)NCC(=O)O.Nc1ccc(CO)cc1>>CC(C)(C)OC(=O)NCC(=O)Nc1ccc(CO)cc1 -US20070265256A1,1,COc1cc2nncc(Br)c2cc1OC.O=C(NC1CC1)c1n[nH]c2c1CNCC2>>COc1cc2nncc(N3CCc4[nH]nc(C(=O)NC5CC5)c4C3)c2cc1OC -US20030055263A1,6,COC(=O)c1cccnc1Nc1nc(-c2ccc3ccccc3c2)cs1>>O=C(O)c1cccnc1Nc1nc(-c2ccc3ccccc3c2)cs1 -US04110536,1,ClCCCN1CCC(c2ccccc2)CC1.O=C1NC(=O)C(Cc2c[nH]c3ccccc23)N1>>O=C1NC(Cc2c[nH]c3ccccc23)C(=O)N1CCCN1CCC(c2ccccc2)CC1 -US20130131039A1,6,CC(C)(C)OC(=O)N1CC(CC#N)(n2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc4nccn34)cn2)C1>>N#CCC1(n2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc4nccn34)cn2)CNC1 -US20150119380A1,2,CS(=O)(=O)Cl.Cc1ccc2nc(-c3cc4ccc(CO)cc4oc3=O)cn2c1>>Cc1ccc2nc(-c3cc4ccc(COS(C)(=O)=O)cc4oc3=O)cn2c1 -US20020156081A1,2,CC(C)(C)OC(=O)N1CC(O)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1 -US08829040B2,3,CN(C)C=O.Fc1cc2cc[nH]c2cc1F>>O=Cc1c[nH]c2cc(F)c(F)cc12 -US20150141409A1,1,Cc1oc(CCBr)nc1-c1ccccc1.O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1>>Cc1oc(CCOC(=O)C(Cc2cc(=O)[nH]c3ccccc23)NC(=O)c2ccc(Cl)cc2)nc1-c1ccccc1 -US20070015774A1,3,Brc1ccc(Br)nc1.CON(C)C(=O)c1cc(Cl)cc(Cl)c1>>O=C(c1cc(Cl)cc(Cl)c1)c1ccc(Br)cn1 -US08026260B2,2,CC(C)(C)OC(=O)Nc1cn(-c2ccccc2)nc1N.O=C(NCc1ccc(C(=O)O)cc1)OCc1cccnc1>>CC(C)(C)OC(=O)Nc1cn(-c2ccccc2)nc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 -US20080096861A1,1,CC(C)(C)OC(=O)N1CCC(CCl)C1.CN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21>>CN(Cc1nc2ccccc2n1CC1CCN(C(=O)OC(C)(C)C)C1)C1CCCc2cccnc21 -US05102884,2,CN(C)c1ccccc1C(N)=O.Cc1cc(N=C=O)ccc1Oc1ncc(Br)cn1>>Cc1cc(NC(=O)NC(=O)c2ccccc2N(C)C)ccc1Oc1ncc(Br)cn1 -US04950674,1,ClCCCBr.Oc1ccc(-c2ccccc2)cc1>>ClCCCOc1ccc(-c2ccccc2)cc1 -US20100120770A1,6,Cc1ccnc(Nc2ncc(Sc3ccnc(C(=O)NCC4(c5ccncc5)CCN(C(=O)OC(C)(C)C)CC4)c3F)s2)c1>>Cc1ccnc(Nc2ncc(Sc3ccnc(C(=O)NCC4(c5ccncc5)CCNCC4)c3F)s2)c1 -US08071592B2,1,C=CCI.O=c1[nH]c2cc(F)cnc2s1>>C=CCn1c(=O)sc2ncc(F)cc21 -US07754745B2,6,CC(C)(C)OC(=O)N1CC[C@@H](Oc2ccccc2C(F)(F)F)C1>>FC(F)(F)c1ccccc1O[C@H]1CCNC1 -US20080318874A1,9,OC(c1ccc(Cl)cc1)c1ccccc1OCc1ccccc1>>Clc1ccc(Cc2ccccc2OCc2ccccc2)cc1 -US05538966,7,COC(=O)C1=Cc2ccsc2S(=O)(=O)N1c1ccc(OC)cc1>>COc1ccc(N2C(CO)=Cc3ccsc3S2(=O)=O)cc1 -US08889716B2,6,CN(C(=O)C1CCOCC1)c1ccc(S(=O)(=O)N2CCC(NC(=O)OC(C)(C)C)CC2)cc1>>CN(C(=O)C1CCOCC1)c1ccc(S(=O)(=O)N2CCC(N)CC2)cc1 -US06969711B2,1,CC(C)c1cc(O)cc(C(C)C)c1NC(=O)CN1CCN(CCO)CC1.CO>>COc1cc(C(C)C)c(NC(=O)CN2CCN(CCO)CC2)c(C(C)C)c1 -US04418208,2,Cc1ccc(N)cc1I.O=C(O)CN(CC(=O)O)CC(=O)O>>Cc1ccc(NC(=O)CN(CC(=O)O)CC(=O)O)cc1I -US20120149737A1,2,COC(=O)c1ccc(N)cc1.O=C(O)c1cc(Cl)c(OC2CCCC2)c(Cl)c1>>COC(=O)c1ccc(NC(=O)c2cc(Cl)c(OC3CCCC3)c(Cl)c2)cc1 -US06452014B1,3,CN(C)C=O.COC(OC)c1cc(C)c(Br)nc1C>>COC(OC)c1cc(C)c(C=O)nc1C -US03984465,1,CC1c2cc(O)c(Cl)c(Cl)c2C(=O)C1(C)C.O=C(O)CI>>CC1c2cc(OCC(=O)O)c(Cl)c(Cl)c2C(=O)C1(C)C -US08088805B2,7,CCOC(=O)c1cc(C2(C)OCCO2)on1>>CC1(c2cc(CO)no2)OCCO1 -US20100009956A1,2,N#Cc1ncc(Br)c(N(N)C2CCCC2)n1.O=C(Cl)c1ccc(-c2ccc(CCl)cc2)nc1>>N#Cc1ncc(Br)c(N(NC(=O)c2ccc(-c3ccc(CCl)cc3)nc2)C2CCCC2)n1 -US20100056791A1,8,COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(CO)nn12>>COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C=O)nn12 -US20040167128A1,2,Nc1cc(Br)ccc1C(=O)O.O=S(=O)(Cl)c1ccccc1>>O=C(O)c1ccc(Br)cc1NS(=O)(=O)c1ccccc1 -US20090312310A1,2,CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)O)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21.CNCCN(C)C(C)=O>>CC(=O)N(C)CCN(C)C(=O)[C@@H]1CCCN1C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1 -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1cc(-c2cnn(CC(C)(C)O)c2)cc(C)c1Br>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(-c6cnn(CC(C)(C)O)c6)cc5C)ccc(F)c43)ccc21 -US06784192B2,6,CCOC(=O)CC1CCCCN1Cc1cccnc1OC>>COc1ncccc1CN1CCCCC1CC(=O)O -US05612377,1,CC(C)(C)OC(=O)NOCc1ccccc1.CI>>CN(OCc1ccccc1)C(=O)OC(C)(C)C -US07968581B2,1,C=CCOCC1(c2ccc(C#N)cc2)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O.CI>>C=CCOCC1(c2ccc(C#N)cc2)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1C -US04816582,9,CCOC(=O)/C(=N\OCCBr)c1csc(N)n1.[N-]=[N+]=[N-]>>CCOC(=O)/C(=N\OCCN=[N+]=[N-])c1csc(N)n1 -US20110112299A1,3,C#Cc1cccc([N+](=O)[O-])c1.OCc1ccccc1I>>O=[N+]([O-])c1cccc(C#Cc2ccccc2CO)c1 -US20100094000A1,6,Cc1nn(CC(F)(F)COC(=O)CNC(=O)OC(C)(C)C)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2>>Cc1nn(CC(F)(F)COC(=O)CN)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 -US20060089367A1,1,COC(=O)c1ccc2[nH]c(COc3ccccc3)cc2c1.FC(F)(F)Sc1ccc(CBr)cc1>>COC(=O)c1ccc2c(c1)cc(COc1ccccc1)n2Cc1ccc(SC(F)(F)F)cc1 -US09156852B2,6,CC(=O)OCc1csc2cncnc12>>OCc1csc2cncnc12 -US20140171430A1,2,Cc1ccnc(N2CC3CNCC3C2)n1.O=C(O)c1ccccc1-c1cccc(F)c1>>Cc1ccnc(N2CC3CN(C(=O)c4ccccc4-c4cccc(F)c4)CC3C2)n1 -US20110257151A1,2,CN1CC(N)C1.COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(C(=O)O)c1)N2>>COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(C(=O)NC3CN(C)C3)c1)N2 -US04769480,1,CN.COc1c(C=O)ccc2c1OCO2>>CNCc1ccc2c(c1OC)OCO2 -US20150166549A1,3,C#CCO.COC(=O)c1ccccc1I>>COC(=O)c1ccccc1C#CCO -US07425554B2,1,CC1(C)C=C(c2cc([N+](=O)[O-])ccc2N2CCNCC2)CC(C)(C)C1.CCCC=O>>CCCCN1CCN(c2ccc([N+](=O)[O-])cc2C2=CC(C)(C)CC(C)(C)C2)CC1 -US20130210795A1,7,COC(=O)c1cccc(C(C)=O)c1>>COC(=O)c1cccc(C(C)O)c1 -US20150210682A1,6,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCOC)cc1CC2C(C)(C)C>>COCCCOc1cc2c(cc1OC)-c1cc(=O)c(C(=O)O)cn1C(C(C)(C)C)C2 -US04689072,1,BrCc1ccccc1.Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1>>Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OCc2ccccc2)n1 -US20150191478A1,3,CC(C)Oc1ccc(-c2cncc3cc(C=O)oc23)cc1.O=C1CSC(=O)N1>>CC(C)Oc1ccc(-c2cncc3cc(/C=C4\SC(=O)NC4=O)oc23)cc1 -US05580885,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1 -US20140364433A1,1,Cc1cc(Cl)n2nc(C)nc2n1.Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2cc(C)nc3nc(C)nn23)c1 -US20090286791A1,1,CCOCCO.O=C(NCCNC(=O)c1cn(-c2ccccc2)nc1C(F)(F)F)c1ccc(Cl)nc1>>CCOCCOc1ccc(C(=O)NCCNC(=O)c2cn(-c3ccccc3)nc2C(F)(F)F)cn1 -US08592444B2,6,COC(=O)/C=C/c1ccc2c(c1)C(=O)NC1(CCN(CCc3ccccc3)CC1)O2>>O=C(O)/C=C/c1ccc2c(c1)C(=O)NC1(CCN(CCc3ccccc3)CC1)O2 -US07989463B2,1,C1COCCN1.COC(=O)C1(c2ccc(Nc3nc(Cl)nc4c3CCC4)cc2)CCC1>>COC(=O)C1(c2ccc(Nc3nc(N4CCOCC4)nc4c3CCC4)cc2)CCC1 -US20080045530A1,2,COC(=O)[C@H]1CN(C(=O)OC(C)(C)C)CCN1.O=C(Cl)c1ccc(Cl)cc1>>COC(=O)[C@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1ccc(Cl)cc1 -US06818394B1,1,O=Cc1cc(O)ccc1[N+](=O)[O-].OCCCBr>>O=Cc1cc(OCCCO)ccc1[N+](=O)[O-] -US07091237B2,7,COC(=O)Cc1cc(-c2ccc(Cl)cc2)oc1C(F)(F)F>>OCCc1cc(-c2ccc(Cl)cc2)oc1C(F)(F)F -US08609659B2,6,COc1cccc(C(c2ccc(C(=O)N3CCCCC3)cc2)N2C3CCC4C2CCC3N4Cc2ccccc2)c1>>COc1cccc(C(c2ccc(C(=O)N3CCCCC3)cc2)N2C3CCC4NC3CCC42)c1 -US04157444,7,O=[N+]([O-])c1cc(Br)ccc1O>>Nc1cc(Br)ccc1O -US20130253186A1,1,Clc1nccnc1OC1CCN(c2ccc3ccccc3n2)CC1.OC1CCNCC1>>OC1CCN(c2nccnc2OC2CCN(c3ccc4ccccc4n3)CC2)CC1 -US20060223835A1,6,O=c1[nH]c(=O)n([C@@H]2C[C@H](COCc3ccccc3)C2)cc1F>>O=c1[nH]c(=O)n([C@@H]2C[C@H](CO)C2)cc1F -US20050203087A1,1,CC1(C)CC(=O)CC(C)(C)C1.CCOC(=O)COc1c(C(=O)OC)sc(-c2ccc(N)cc2)c1Br>>CCOC(=O)COc1c(C(=O)OC)sc(-c2ccc(NC3CC(C)(C)CC(C)(C)C3)cc2)c1Br -US20140275003A1,6,COC(=O)c1cccc(C(C)(C)C#N)c1>>CC(C)(C#N)c1cccc(C(=O)O)c1 -US20090036420A1,2,COc1cccc(N)c1.O=C(O)c1cnc(Cl)c(C(F)(F)F)c1>>COc1cccc(NC(=O)c2cnc(Cl)c(C(F)(F)F)c2)c1 -US04154932,1,CCI.O=C(C1CC1)N1CC[C@]23COCC[C@H]2[C@H]1Cc1ccc(O)cc13>>CCOc1ccc2c(c1)[C@]13CCN(C(=O)C4CC4)[C@H](C2)[C@@H]1CCOC3 -US08198456B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1=C(C#N)C(c2ccc3[nH]nc(N)c3c2)C(C#N)=C(C)N1>>CC1=C(C#N)C(c2ccc3c(c2)c(N)nn3C(=O)OC(C)(C)C)C(C#N)=C(C)N1 -US08084620B2,2,CSCCC(NC(=O)OCc1ccccc1)C(=O)O.Cc1c(N)cccc1Br>>CSCCC(NC(=O)OCc1ccccc1)C(=O)Nc1cccc(Br)c1C -US08178522B2,2,Cc1onc(-c2ccc(F)cn2)c1/C=C/c1ncc(C(=O)O)s1.NC1CCOCC1>>Cc1onc(-c2ccc(F)cn2)c1/C=C/c1ncc(C(=O)NC2CCOCC2)s1 -US20120225859A1,7,CN(C)CCOc1ccc([N+](=O)[O-])cn1>>CN(C)CCOc1ccc(N)cn1 -US20100016396A1,6,C=Cc1c(COC)nn(C)c1Oc1cc(O[C@@H](C)C(=O)OC)c(Cl)cc1Cl>>C=Cc1c(COC)nn(C)c1Oc1cc(O[C@@H](C)C(=O)O)c(Cl)cc1Cl -US20100160379A1,1,Fc1ccc(CCl)nc1.Nc1ccc(-c2cc(Cc3ccc(O)cc3)no2)cn1>>Nc1ccc(-c2cc(Cc3ccc(OCc4ccc(F)cn4)cc3)no2)cn1 -US06359138B1,7,COC(=O)C1Cc2cc(OC)ccc2N1>>COc1ccc2c(c1)CC(CO)N2 -US20100120775A1,3,CC1(C)OB(c2ccc(O)cc2)OC1(C)C.COC(=O)c1cc2ccc(OS(=O)(=O)C(F)(F)F)cc2cn1>>COC(=O)c1cc2ccc(-c3ccc(O)cc3)cc2cn1 -US20100048537A1,1,Cc1cc2c(s1)CN(C)CCC2O.Fc1ccc(Cl)c(Cl)c1>>Cc1cc2c(s1)CN(C)CCC2Oc1ccc(Cl)c(Cl)c1 -USH0001638,1,CCCCCCCCOc1ccc(C(=O)O)cc1.Oc1cc(Cl)c(Cl)cc1Cl>>CCCCCCCCOc1ccc(C(=O)Oc2cc(Cl)c(Cl)cc2Cl)cc1 -US20150183799A1,3,CC(c1ccc(B(O)O)cc1)N(C)C.COc1c(F)c(F)c2[nH]c(=O)c3sccc3c2c1Br>>COc1c(F)c(F)c2[nH]c(=O)c3sccc3c2c1-c1ccc(C(C)N(C)C)cc1 -US06787560B2,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COc1cccc(C=O)c1OC>>COC=Cc1cccc(OC)c1OC -US20130005964A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)NCc1ccc([N+](=O)[O-])cc1 -US03997572,1,Cc1ncc([N+](=O)[O-])n1CCO.O=C1NC(=O)C2c3cccc4cccc(c34)C12>>Cc1ncc([N+](=O)[O-])n1CCN1C(=O)C2c3cccc4cccc(c34)C2C1=O -US20080300241A9,7,C=CCN1c2ccc3nc(OC(C)C)cc(C(F)(F)F)c3c2OC[C@H]1CC>>CCCN1c2ccc3nc(OC(C)C)cc(C(F)(F)F)c3c2OC[C@H]1CC -US20100298384A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC[C@H]1CN(c2ccc(C(N)=O)c(F)c2)C(=O)O1>>CC(C)(C)OC(=O)NC[C@H]1CN(c2ccc(C(N)=O)c(F)c2)C(=O)O1 -US07253285B2,1,C1COCCN1.Clc1ccnc2ccc(Br)cc12>>Brc1ccc2nccc(N3CCOCC3)c2c1 -US20090264336A1,1,COC(=O)c1cc(O)cc(OCc2ccccc2)c1.OC(CF)CF>>COC(=O)c1cc(OCc2ccccc2)cc(OC(CF)CF)c1 -US07001897B2,2,CS(=O)(=O)Cl.O=C(N[C@H]1CCN(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1)c1coc(N2CC(O)C2)n1>>CS(=O)(=O)OC1CN(c2nc(C(=O)N[C@H]3CCN(C(=O)OCc4ccc([N+](=O)[O-])cc4)C3)co2)C1 -US03954734,1,Clc1cccc(N2CCNCC2)c1.N#Cc1ccc(-c2ccc(F)cc2)[nH]c1=O>>N#Cc1ccc(-c2ccc(N3CCN(c4cccc(Cl)c4)CC3)cc2)[nH]c1=O -US06218429B1,1,C=CCBr.CCC(=O)NCCc1c[nH]c2ccc(O)cc12>>C=CCOc1ccc2[nH]cc(CCNC(=O)CC)c2c1 -US20130345258A1,6,CC(=O)SC1CC(C)OC(C)C1>>C[C@H]1CC(S)C[C@@H](C)O1 -US20080200448A1,2,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCC1=O.NS(=O)(=O)Cc1ccc(SC(F)(F)F)cc1>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccc(SC(F)(F)F)cc3)CC2)nc1CN1CCCC1=O -US20150266867A1,1,CC1(C)OC[C@@H](C=O)O1.COc1ccc(CN)c(OC)c1>>COc1ccc(C/N=C/[C@@H]2COC(C)(C)O2)c(OC)c1 -US20040236110A1,1,Cc1[nH]c2ccc(Br)cc2c1C.Fc1cccnc1>>Cc1c(C)n(-c2cccnc2)c2ccc(Br)cc12 -US20150031703A1,6,COc1cc(OC)c(F)c(COc2cnc(Nc3cc(COC4CCCCO4)n(C)n3)nc2)c1F>>COc1cc(OC)c(F)c(COc2cnc(Nc3cc(CO)n(C)n3)nc2)c1F -US06025390,2,CCN(CC)CCCN.CO/C(=C\C=C\c1cc2ccccc2o1)C(=O)O>>CCN(CC)CCCNC(=O)/C(=C/C=C/c1cc2ccccc2o1)OC -US20130116288A1,6,Cc1c(N[C@@H](c2nnc(-c3ccccc3)s2)[C@H](C)O[Si](C)(C)C(C)(C)C)ccc(C#N)c1Cl>>Cc1c(N[C@@H](c2nnc(-c3ccccc3)s2)[C@H](C)O)ccc(C#N)c1Cl -US20070191603A1,6,COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ncc(C(=O)Nc3ccc(C(=O)OC(C)(C)C)cc3)cc21>>COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ncc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 -US20150246922A1,3,Cc1c2n(c3c(Br)cc(F)cc13)CCNC2=O.OB(O)c1ccc(Cl)c(Cl)c1>>Cc1c2n(c3c(-c4ccc(Cl)c(Cl)c4)cc(F)cc13)CCNC2=O -US20110105470A1,2,O=C(Cl)c1cccc(Cl)c1.O=C1C(=O)c2ccc(-c3cccnc3)cc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccc(-c3cccnc3)cc2C2=C1SCC1(CCN(C(=O)c3cccc(Cl)c3)CC1)O2 -US06727264B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CCCCN)CC2)c1.O=C(Cl)C(c1ccccc1)c1ccccc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCNC(=O)C(c3ccccc3)c3ccccc3)CC2)c1 -US20100284970A1,1,C1CCNC1.ClCc1nc2ccccc2n1Cc1ccc(Cl)cc1>>Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc32)cc1 -US07820699B2,2,CC(C)(C)OC(=O)N1CC[C@H](CN)C1.O=C(O)c1cc(Br)c(Br)[nH]1>>CC(C)(C)OC(=O)N1CC[C@H](CNC(=O)c2cc(Br)c(Br)[nH]2)C1 -US05093353,1,CCCCCCBr.CCCc1c(O)ccc2c1OC(CCC(=O)OCC)(CCC(=O)OCC)CC2=O>>CCCCCCOc1ccc2c(c1CCC)OC(CCC(=O)OCC)(CCC(=O)OCC)CC2=O -US04649146,3,CNc1nc(C=O)c(-c2ccncc2)s1.c1ccc([P+](Cc2ccncc2)(c2ccccc2)c2ccccc2)cc1>>CNc1nc(C=Cc2ccncc2)c(-c2ccncc2)s1 -US20140187554A1,1,CC(C)O.O=[N+]([O-])c1ccccc1O>>CC(C)Oc1ccccc1[N+](=O)[O-] -US08461179B1,1,CCn1c(=O)c(-c2cc(NC(=O)Nc3ccc(F)c(CN4CCN(C)CC4)c3)c(F)cc2C)cc2cnc(Cl)cc21.NC=O>>CCn1c(=O)c(-c2cc(NC(=O)Nc3ccc(F)c(CN4CCN(C)CC4)c3)c(F)cc2C)cc2cnc(NC=O)cc21 -US04092362,9,CCCCCC1C(=O)CCC1C(C(C)=O)C(=O)OCC>>CCCCCC1C(=O)CCC1CC(C)=O -US20100249182A1,1,Nc1ccc(O)cc1.O=[N+]([O-])c1cccc2c(Cl)ccnc12>>Nc1ccc(Oc2ccnc3c([N+](=O)[O-])cccc23)cc1 -US20130005721A1,4,C#CC(O)(CC)C(F)(F)F.CCOC(=O)c1cc2cc(CN=[N+]=[N-])ccn2c1-c1ccc(F)nc1>>CCOC(=O)c1cc2cc(Cn3cc(C(O)(CC)C(F)(F)F)nn3)ccn2c1-c1ccc(F)nc1 -US06727264B1,1,Clc1ccc2cc[nH]c2c1.Clc1ccccc1I>>Clc1ccc2ccn(-c3ccccc3Cl)c2c1 -US20120172333A1,1,CCOC(=O)c1[nH]ccc1NC(C)=O.COc1ccc(B(O)O)cc1>>CCOC(=O)c1c(NC(C)=O)ccn1-c1ccc(OC)cc1 -US08685989B2,6,Cc1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1NC(=O)OC(C)(C)C>>Cc1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1N -US20150104384A1,6,COC(=O)c1ccc2ncnn2c1>>O=C(O)c1ccc2ncnn2c1 -US20100099657A2,2,CC1(C)COC(CSCC(=O)O)(c2ccccc2)OC1.O=C1N[C@@H](c2ccccc2)CO1>>CC1(C)COC(CSCC(=O)N2C(=O)OC[C@@H]2c2ccccc2)(c2ccccc2)OC1 -US20030220350A1,2,CC(Nc1ccc(C(C)(C)C)cc1)c1ccc(C(=O)Nc2nn[nH]n2)cc1.O=C=Nc1ccc(OC(F)(F)F)cc1>>CC(c1ccc(C(=O)Nc2nn[nH]n2)cc1)N(C(=O)Nc1ccc(OC(F)(F)F)cc1)c1ccc(C(C)(C)C)cc1 -US20090099176A1,2,COC(=O)CN1C(=O)[C@H](N)Cc2ccccc21.O=C(O)c1cc2cc(Cl)ncc2[nH]1>>COC(=O)CN1C(=O)[C@H](NC(=O)c2cc3cc(Cl)ncc3[nH]2)Cc2ccccc21 -US08969375B2,1,Fc1cccc(CBr)c1.N#Cc1c[nH]c2cc(Br)c(F)cc12>>N#Cc1cn(Cc2cccc(F)c2)c2cc(Br)c(F)cc12 -US20120070410A1,1,C=[N+]=[N-].O=C(O)C(CO)(CO)CO>>COC(=O)C(CO)(CO)CO -US08889878B2,2,COC(=O)c1cnc(I)cc1C(F)(F)F.NC1CC1>>O=C(NC1CC1)c1cnc(I)cc1C(F)(F)F -US20090018134A1,2,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)c(Cl)c3)CC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)c(Cl)c3)CC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US07393959B2,1,Clc1cccc(Cl)n1.c1ccc(-c2cc[nH]c2)nc1>>Clc1cccc(-n2ccc(-c3ccccn3)c2)n1 -US20070155805A1,1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.Cc1c(CCCBr)sc2cc(Br)ccc12>>CCOC(=O)C(C)(C)Oc1ccc(OCCCc2sc3cc(Br)ccc3c2C)cc1C -US08946235B2,1,CN(C)C1CNC1.COc1cc(F)c([N+](=O)[O-])cc1Nc1nccc(-c2cnn3ccccc23)n1>>COc1cc(N2CC(N(C)C)C2)c([N+](=O)[O-])cc1Nc1nccc(-c2cnn3ccccc23)n1 -US20090069302A1,2,COc1ccc(S(=O)(=O)Cl)cc1.COc1ccc(S(=O)(=O)N2C[C@H](C)NC[C@@H]2C)cc1OC>>COc1ccc(S(=O)(=O)N2C[C@H](C)N(S(=O)(=O)c3ccc(OC)c(OC)c3)C[C@@H]2C)cc1 -US20090264445A1,7,O=[N+]([O-])c1ccn(C[C@@H](O)CO)n1>>Nc1ccn(C[C@@H](O)CO)n1 -US20080015202A1,2,CC(=O)Nc1nc(CCc2ccc(CCN)cc2)cs1.CS(=O)(=O)Cl>>CC(=O)Nc1nc(CCc2ccc(CCNS(C)(=O)=O)cc2)cs1 -US20110306597A1,6,COc1ccccc1-c1nnc(CCNC(=O)OC(C)(C)C)o1>>COc1ccccc1-c1nnc(CCN)o1 -US20070129334A1,1,CC(C)(C)OC(=O)NCCCl.COc1ccc(I)c(Sc2nc3c(N)ncnc3[nH]2)c1>>COc1ccc(I)c(Sc2nc3c(N)ncnc3n2CCNC(=O)OC(C)(C)C)c1 -US20130065914A1,1,Cc1c(Br)sc2ncnc(Cl)c12.Nc1ccc(F)cc1OC1CCOCC1>>Cc1c(Br)sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c12 -US20150018343A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1CNCCO1>>CC(C)(C)OC(=O)N1CCOC(CO)C1 -US08853238B2,4,CCSc1ccccc1C(=O)O.CNc1c(N)cc(C(F)(F)F)cc1Br>>CCSc1ccccc1-c1nc2cc(C(F)(F)F)cc(Br)c2n1C -US20130237515A1,1,CNC.COc1ccc(COc2cnn(CC(=O)c3ccc(CBr)cc3C)c(=O)c2)nc1>>COc1ccc(COc2cnn(CC(=O)c3ccc(CN(C)C)cc3C)c(=O)c2)nc1 -US20080139530A1,2,CC(O)c1cc(Br)ccc1N.O=C(Cl)CCl>>CC(O)c1cc(Br)ccc1NC(=O)CCl -US20060167052A1,2,CN=C=O.FC(F)(F)c1cc(CO[C@H]2CCNC[C@H]2Cc2ccccc2)cc(C(F)(F)F)c1>>CNC(=O)N1CC[C@H](OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccccc2)C1 -US05110818,1,CN.CN(C)c1nc(Cl)nc2c1ncn2Cc1ccccc1F>>CNc1nc(N(C)C)c2ncn(Cc3ccccc3F)c2n1 -US08354540B2,6,CC(C)(C)OC(=O)N1CCC(c2csc(Nc3ncc(Br)cc3Oc3ccccc3)n2)CC1>>Brc1cnc(Nc2nc(C3CCNCC3)cs2)c(Oc2ccccc2)c1 -US20120065195A1,3,CN1C(=O)C2(CC(C)(C)Cc3ccc(Br)cc32)N=C1N.N#CCCC[Zn+]>>CN1C(=O)C2(CC(C)(C)Cc3ccc(CCCC#N)cc32)N=C1N -US09096524B2,2,N#Cc1ccc(NC2CCNCC2)cc1C(F)(F)F.O=C(O)CCCN1CCN(c2ccc(C(F)(F)F)cc2)CC1>>N#Cc1ccc(NC2CCN(C(=O)CCCN3CCN(c4ccc(C(F)(F)F)cc4)CC3)CC2)cc1C(F)(F)F -US20080207703A1,6,COCCOCc1csc(NC(=O)OC(C)(C)C)n1>>COCCOCc1csc(N)n1 -US20100035864A1,1,O=C(Nc1ccc(N2CCCNCC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F.O=C(O)c1ccc(CBr)cc1>>O=C(O)c1ccc(CN2CCCN(c3ccc(NC(=O)c4nc(-c5ccccc5)oc4C(F)(F)F)cc3)CC2)cc1 -US05523299,3,CN(C)C=O.COc1c(Br)cc(Br)cc1-c1ccc[nH]1>>COc1c(Br)cc(Br)cc1-c1ccc(C=O)[nH]1 -US20120053171A1,9,NC(=O)C(CCCCl)c1ccc(Cl)cc1C(F)(F)F>>N#CC(CCCCl)c1ccc(Cl)cc1C(F)(F)F -US04853387,1,CN(CCBr)C(c1ccccc1)(c1ccccc1)c1ccccc1.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>CN(CCN1CCC(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20130225673A1,6,CCc1oc2ccccc2c1C(=O)c1ccc(OC)cc1>>CCc1oc2ccccc2c1C(=O)c1ccc(O)cc1 -US20040087798A1,2,Nc1ccc(OCc2ccccn2)cc1.O=C(O)c1cccc2c1Cc1ccccc1-2>>O=C(Nc1ccc(OCc2ccccn2)cc1)c1cccc2c1Cc1ccccc1-2 -US20080090794A1,1,C1COCCN1.COC(=O)C(Br)c1ccccc1>>COC(=O)C(c1ccccc1)N1CCOCC1 -US06197798B1,7,O=C(Nc1ccc2c(c1)CCC2)c1cc([N+](=O)[O-])ccc1-c1cccs1>>Nc1ccc(-c2cccs2)c(C(=O)Nc2ccc3c(c2)CCC3)c1 -US20080076760A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(F)c([N+](=O)[O-])c1>>Cc1ccc(S(=O)(=O)Nc2ccc(F)c([N+](=O)[O-])c2)cc1 -US20040266843A1,2,CN1CCNCC1.Cc1cc(C(=O)O)[nH]c1C=O>>Cc1cc(C(=O)N2CCN(C)CC2)[nH]c1C=O -US20060019944A1,6,O=C1c2ccccc2C(=O)N1[C@@H]1CC[C@](COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)C1>>N[C@@H]1CC[C@](COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)C1 -US20040110945A1,2,CO.O=C(O)Cc1ccccc1[N+](=O)[O-]>>COC(=O)Cc1ccccc1[N+](=O)[O-] -US06982348B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NC(Cc2cccc(CC(F)(F)C(F)F)c2)C(c2ccc(F)cc2)O1>>CC(C)(C)OC(=O)N1C(=O)OC(c2ccc(F)cc2)C1Cc1cccc(CC(F)(F)C(F)F)c1 -US20120058989A1,3,CC(C)(C)OC(=O)CC[C@@H](C=O)NC(=O)OCc1ccccc1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CO/C=C/[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1 -US07576099B2,3,C=C(C)C(F)(F)F.COC(=O)c1ccc(I)cc1>>COC(=O)c1ccc(/C=C(\C)C(F)(F)F)cc1 -US20040162303A1,1,CC(C)(N)CO.COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N>>COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCNC(C)(C)CO)CC2)nc1N -US04716169,6,COc1cc(NC(C)=O)ccc1-c1cn2ncccc2n1>>COc1cc(N)ccc1-c1cn2ncccc2n1 -US05789425,1,C#CCBr.O=C1NCCN1c1cccnc1>>C#CCN1CCN(c2cccnc2)C1=O -US07015218B1,1,CC(C)CBr.O=[N+]([O-])c1ccc(O)cc1>>CC(C)COc1ccc([N+](=O)[O-])cc1 -US20090062317A1,1,CC(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.Clc1nc(NCc2ccccn2)c2ccccc2n1>>CC(=O)Nc1cccc(C2CCN(CCCNc3nc(NCc4ccccn4)c4ccccc4n3)CC2)c1 -US20090023746A1,1,CN.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(Cc3ccc(OCCCl)cc3)ccc2c1>>CNCCOc1ccc(Cn2ccc3cc(-c4cc(C(=O)NC5CC5)ccc4C)ccc3c2=O)cc1 -US20050043336A1,6,CC(C)(C)OC(=O)c1ccc([N+](=O)[O-])cc1C#C[Si](C)(C)C>>C#Cc1cc([N+](=O)[O-])ccc1C(=O)OC(C)(C)C -US07179823B1,1,COC(=O)CCc1cn(Cc2ccc(O)cc2)nc1-c1ccccc1.ClCc1noc(-c2ccccc2)n1>>COC(=O)CCc1cn(Cc2ccc(OCc3noc(-c4ccccc4)n3)cc2)nc1-c1ccccc1 -US07101878B1,6,COC(=O)c1ccc(Cc2cc3c(cc2C)C(C)(C)CCC3(C)C)o1>>Cc1cc2c(cc1Cc1ccc(C(=O)O)o1)C(C)(C)CCC2(C)C -US20120190665A1,7,COc1ccc(Cl)cc1-c1c([N+](=O)[O-])cnn1CCC(C)C>>COc1ccc(Cl)cc1-c1c(N)cnn1CCC(C)C -US20110144081A1,2,CC1(C(=O)N2CCC(C(=O)O)CC2)CC1.CN(C(=O)OC(C)(C)C)[C@H]1CNC[C@@H]1c1ccc(Cl)c(Cl)c1>>CN(C(=O)OC(C)(C)C)[C@H]1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)C[C@@H]1c1ccc(Cl)c(Cl)c1 -US20150011591A1,4,Nc1ccccc1N.O=C(O)CCc1ccccc1>>c1ccc(CCc2nc3ccccc3[nH]2)cc1 -US20090028858A1,6,CC(C)C(c1nc2ccccc2cc1Cc1ccccc1)N1C(=O)c2ccccc2C1=O>>CC(C)C(N)c1nc2ccccc2cc1Cc1ccccc1 -US20120040960A1,1,CSc1ccc(C2=CCC(=O)CC2)cc1.O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CNC1>>CSc1ccc(C2=CCC(N3CC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cc1 -US20080132477A1,6,C=CCN(C(=O)OC(C)(C)C)c1cccc(C(=O)OCC)c1>>C=CCN(C(=O)OC(C)(C)C)c1cccc(C(=O)O)c1 -US20070265254A1,2,CNCc1ccccc1.O=C(O)c1ccc2cc(O)ccc2c1>>CN(Cc1ccccc1)C(=O)c1ccc2cc(O)ccc2c1 -US20090264445A1,10,CCOC(=O)C=C(C)Oc1cc(C)ccc1F.O=C1CCC(=O)N1Br>>CCOC(=O)/C=C(\CBr)Oc1cc(C)ccc1F -US20040229897A1,2,CCCCc1nc2c(N)nc3ccccc3c2n1CCCCN.O=C(Cl)c1ccccc1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCCNC(=O)c1ccccc1 -US20020037891A1,6,CCOC(=O)c1cn(C2CC2)c2nc3c(F)c(N4CCN(Cc5ccco5)CC4)c(F)cc3cc2c1=O>>O=C(O)c1cn(C2CC2)c2nc3c(F)c(N4CCN(Cc5ccco5)CC4)c(F)cc3cc2c1=O -US20140357614A1,1,CC(C)(C)OC(=O)NC1CN(c2ccnc(Cl)n2)C1.CCCCN>>CCCCNc1nccc(N2CC(NC(=O)OC(C)(C)C)C2)n1 -US07235510B2,3,C=Cc1ccccc1.CC(=O)c1ccc(Br)cc1>>CC(=O)c1ccc(/C=C/c2ccccc2)cc1 -US05702887,1,Nc1ccccc1.O=C(O)c1cc2ccccc2cc1O>>O=C(O)c1cc2ccccc2cc1Nc1ccccc1 -US08481725B2,2,COC(=O)C1(N)CCCCC1.O=C(O)c1ccoc1>>COC(=O)C1(NC(=O)c2ccoc2)CCCCC1 -US06498151B2,7,COC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1>>NS(=O)(=O)c1cc(CO)ccc1Cl -US05372931,2,CC(=O)OC(C)=O.Nc1ccc(O)c2ccccc12>>CC(=O)Nc1ccc(O)c2ccccc12 -US20110065707A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CC(C)c1ccc(N)cc1>>CC(C)c1ccc(NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US04042397,2,CCCCN=C=O.Nc1ccc(S(N)(=O)=O)cc1>>CCCCNC(=O)Nc1ccc(S(N)(=O)=O)cc1 -US20130165436A1,6,COc1ncc(N2CCOc3cnc(O[C@H]4CCN(C(=O)OC(C)(C)C)C4)cc32)cc1C>>COc1ncc(N2CCOc3cnc(O[C@H]4CCNC4)cc32)cc1C -US20060100245A1,3,CC(C)(C)c1ccc(NC(=O)c2ccc(Br)cn2)cc1.OB(O)c1ccccc1Cl>>CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ccccc3Cl)cn2)cc1 -US08309581B2,1,BrCC1CCCC1.Oc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2n1Cc1cccc(Cl)c1>>Fc1cc2nc(-c3ccc(Cl)cc3OCC3CCCC3)n(Cc3cccc(Cl)c3)c2cc1F -US04885027,2,NC1CC1.O=S(=O)(Cl)Cc1cccc(C(F)(F)F)c1>>O=S(=O)(Cc1cccc(C(F)(F)F)c1)NC1CC1 -US07589199B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(N2CCN[C@H](CO)C2)ccc1Cl>>COc1cc(N2CCN(C(=O)OC(C)(C)C)[C@@H](CO)C2)ccc1Cl -US06245746B1,2,CN(Cc1ccccc1)[C@@H](CCCNC(=O)OC(C)(C)C)C(=O)O.Cc1ccc(CCN)cc1>>Cc1ccc(CCNC(=O)[C@H](CCCNC(=O)OC(C)(C)C)N(C)Cc2ccccc2)cc1 -US20140213586A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=Cc1c[nH]c2cc(N3CCOCC3)ccc12>>CC(C)(C)OC(=O)n1cc(C=O)c2ccc(N3CCOCC3)cc21 -US04250183,2,CCOC(=O)CCCNc1c(C)cccc1C.COc1ccc(N(CCCC(=O)O)C(=O)c2ccc(Cl)cc2)cc1>>CCOC(=O)CCCN(C(=O)CCCN(C(=O)c1ccc(Cl)cc1)c1ccc(OC)cc1)c1c(C)cccc1C -US06051712,1,C=CCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1.COc1cc(CCl)c(OC)c2ccccc12>>C=CCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2cc(OC)c3ccccc3c2OC)cc1 -US08158790B2,6,CC(C)(C)OC(=O)N1CC(=O)N(c2c(F)cccc2F)CC1(C)C>>CC1(C)CN(c2c(F)cccc2F)C(=O)CN1 -US07635711B2,2,NC(Cc1c[nH]c2ccccc12)C(F)(F)F.O=S(=O)(Cl)c1c(Cl)cc(Br)cc1Cl>>O=S(=O)(NC(Cc1c[nH]c2ccccc12)C(F)(F)F)c1c(Cl)cc(Br)cc1Cl -US20130012523A1,2,CCOC(=O)C(=O)Nc1cc(C(=O)OC)ccc1Cl.COC(CN)OC>>COC(=O)c1ccc(Cl)c(NC(=O)C(=O)NCC(OC)OC)c1 -US20110071150A1,4,Cc1nc(-c2ccccc2)sc1-c1ccc(N)c(C#Cc2ccccc2Cl)c1>>Cc1nc(-c2ccccc2)sc1-c1ccc2[nH]c(-c3ccccc3Cl)cc2c1 -US20150133471A1,3,Brc1cncc(Br)c1.C#CCC>>CCC#Cc1cncc(Br)c1 -US20090227601A1,9,CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CCCC1=O>>CC(C)(C)OC(=O)N1CCCC(=O)CCC1 -US20110301170A1,9,CCCSc1nccc(Cl)n1.NN>>CCCSc1nccc(NN)n1 -US07829714B2,6,CC(C)(C)OC(=O)NCCNC(=O)C1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(C(=O)NCCN)CC[C@@H]12 -US05556977,7,C=CCc1cc(N2CCN(c3ccncc3)CC2)ccc1O>>CCCc1cc(N2CCN(c3ccncc3)CC2)ccc1O -US05998433,2,CCCCCCCc1ccc(C(=O)O)cc1.c1cc2c(o1)CNCC2>>CCCCCCCc1ccc(C(=O)N2CCc3ccoc3C2)cc1 -US07348348B2,3,Clc1ccccc1Br.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccccc2Cl)cc1 -US06348474B1,6,CCOC(=O)c1ccc2nc(C)c(=O)n(Cc3ccc(Cl)cc3Cl)c2c1>>Cc1nc2ccc(C(=O)O)cc2n(Cc2ccc(Cl)cc2Cl)c1=O -US20130324579A1,7,COc1ccc2c(c1)CCN2CCCn1cc([N+](=O)[O-])cn1>>COc1ccc2c(c1)CCN2CCCn1cc(N)cn1 -US20060183745A1,3,CC1CCCN1Cc1cc(C(F)(F)F)ccc1B(O)O.Nc1nc2c(Oc3cc(I)ncn3)cccc2s1>>CC1CCCN1Cc1cc(C(F)(F)F)ccc1-c1cc(Oc2cccc3sc(N)nc23)ncn1 -US07842685B2,2,CNCCOC.O=C(O)c1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1>>COCCN(C)C(=O)c1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 -US20100144751A1,1,O=C(N[C@H]1CCNC[C@H]1F)OCc1ccccc1.O=[N+]([O-])c1cc(F)ccc1F>>O=C(N[C@H]1CCN(c2ccc(F)cc2[N+](=O)[O-])C[C@H]1F)OCc1ccccc1 -US20070191420A1,2,Nc1ccncn1.O=C(NCc1ccc(C(=O)O)cc1)OCc1ccccc1>>O=C(NCc1ccc(C(=O)Nc2ccncn2)cc1)OCc1ccccc1 -US20100075994A1,1,CCC(C)(C)c1ccc(O)c(Cl)c1.ClCC1CO1>>CCC(C)(C)c1ccc(OCC2CO2)c(Cl)c1 -US20060079572A1,2,CCC(O)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)C(O[SiH](C)C)C(C(C)(C)C)CCC(C)(O)C(OC(C)=O)C=CC1C.CCOCC(=O)O>>CCOCC(=O)OC(CC)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)C(O[SiH](C)C)C(C(C)(C)C)CCC(C)(O)C(OC(C)=O)C=CC1C -US04906662,2,CC(C)(C)c1cc(Nc2ccccc2C(=O)O)cc(C(C)(C)C)c1O.NCc1ccccc1>>CC(C)(C)c1cc(Nc2ccccc2C(=O)NCc2ccccc2)cc(C(C)(C)C)c1O -US20070232628A1,6,CC(C)CC(C(=O)Nc1ccc(C(C)C)cc1)C1(C)OCCO1>>CC(=O)C(CC(C)C)C(=O)Nc1ccc(C(C)C)cc1 -US06407094B1,7,CC(C)(C)OC(=O)Nc1cc(N2CCC(OCCOC3CCCCO3)CC2)c(-c2ccc(F)cc2)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(N2CCC(OCCOC3CCCCO3)CC2)c(-c2ccc(F)cc2)cc1N -US07138414B2,7,Cc1nnc(-c2ccc(Cl)c([N+](=O)[O-])c2)[nH]1>>Cc1nnc(-c2ccc(Cl)c(N)c2)[nH]1 -US20080227770A1,9,COc1cccc([C@H]2O[C@H](CC(N)=O)C(=O)N(CC(C)(C)C)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC#N)C(=O)N(CC(C)(C)C)c3ccc(Cl)cc32)c1OC -US20070054903A1,3,Brc1cccc2cnccc12.COC(=O)c1cccc2cc(B3OC(C)(C)C(C)(C)O3)ccc12>>COC(=O)c1cccc2cc(-c3cccc4cnccc34)ccc12 -US20080274892A1,7,CC1(C)OC(=O)N(Cc2ccccc2[N+](=O)[O-])C1=O>>CC1(C)OC(=O)N(Cc2ccccc2[N+](=O)[O-])C1O -US06544989B2,7,COC(=O)Cc1ccc(F)c([N+](=O)[O-])c1>>COC(=O)Cc1ccc(F)c(N)c1 -US08138189B2,1,CC(c1cc(O)ccc1Cl)C(O)(c1ccnc(Cl)c1)C(F)(F)F.COC(=O)c1ccc(Cl)nn1>>COC(=O)c1ccc(Oc2ccc(Cl)c(C(C)C(O)(c3ccnc(Cl)c3)C(F)(F)F)c2)nn1 -US20080194624A1,2,C=CCCC(c1cc2cc(Oc3ccccc3)ccc2nc1N)C1CCOCC1.CC(=O)OC(C)=O>>C=CCCC(c1cc2cc(Oc3ccccc3)ccc2nc1NC(C)=O)C1CCOCC1 -US20110086860A1,6,COc1cc(C2OCCO2)ccc1-n1ccnc1Cl>>COc1cc(C=O)ccc1-n1ccnc1Cl -US04391818,7,CCC(C(=O)O)c1ccc([N+](=O)[O-])cc1>>CCC(CO)c1ccc([N+](=O)[O-])cc1 -US20150175562A1,1,FC(F)(F)CI.Oc1ccc(Br)c2ccccc12>>FC(F)(F)COc1ccc(Br)c2ccccc12 -US20150011548A1,7,CC(=O)Nc1cc(-c2ccc(F)cc2F)cc([N+](=O)[O-])c1>>CC(=O)Nc1cc(N)cc(-c2ccc(F)cc2F)c1 -US20150252038A1,1,CC(C)=O.COC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3cc(F)ccc3N)CC2)cc1F>>COC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3cc(F)ccc3NC(C)C)CC2)cc1F -US07582769B2,1,N[C@H]1CC[C@@H](O)CC1.O=C1CCCCC1>>O[C@@H]1CC[C@H](NC2CCCCC2)CC1 -US08859577B2,6,CC(C)n1ncc2c1C(=O)CC1(CCN(Cc3ccccc3)CC1)O2>>CC(C)n1ncc2c1C(=O)CC1(CCNCC1)O2 -US20150045378A1,6,COC(=O)CC(c1cccc(OCc2cc(OCC(C)C)c(-c3cc(OC)ccc3F)cn2)c1)C1CC1>>COc1ccc(F)c(-c2cnc(COc3cccc(C(CC(=O)O)C4CC4)c3)cc2OCC(C)C)c1 -US05057525,4,C=CCC(OC)(c1ccc(F)cc1)C1CC1.O=C(OO)c1cccc(Cl)c1>>COC(CC1CO1)(c1ccc(F)cc1)C1CC1 -US05646313,2,CC(=O)SC/C(=C/c1ccccc1)C(=O)O.NCCC(=O)OCc1ccccc1>>CC(=O)SC/C(=C/c1ccccc1)C(=O)NCCC(=O)OCc1ccccc1 -US20090209522A1,2,CCOC(=O)c1coc(Oc2ccc3c(c2)C(C)(C)CC3)n1.COc1nc(NCCN(C)C)nc(OC)c1N>>COc1nc(NCCN(C)C)nc(OC)c1NC(=O)c1coc(Oc2ccc3c(c2)C(C)(C)CC3)n1 -US06528528B2,2,COc1ccc(C(=O)Nc2ccc(F)c(F)c2)cc1N.S=C=Nc1cc(Cl)cc(Cl)c1>>COc1ccc(C(=O)Nc2ccc(F)c(F)c2)cc1NC(=S)Nc1cc(Cl)cc(Cl)c1 -US06642418B1,9,COC(=O)C(C(=O)c1sc(C)c(OC)c1F)C(=O)C1CC1>>COc1c(C)sc(C(=O)CC(=O)C2CC2)c1F -US20120277237A1,3,C#CCCc1nc2ccccc2s1.Fc1ccc(Br)nc1>>Fc1ccc(C#CCCc2nc3ccccc3s2)nc1 -US04032322,4,CC(C)C(N)=C(C#N)C(N)=S>>CC(C)c1nsc(N)c1C#N -US06943183B2,2,Nc1c(O[C@H](Cn2ccnc2)c2ccccc2)ccc2c1CCCC2=O.O=S(=O)(Cl)c1ccccc1>>O=C1CCCc2c1ccc(O[C@H](Cn1ccnc1)c1ccccc1)c2NS(=O)(=O)c1ccccc1 -US04611061,9,OCCc1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1>>OCCc1ccc(O)c(-n2nc3ccccc3n2)c1 -US20130237705A1,2,CCCNCCO.COc1ccc(N2CCN(c3ccc(N=C=O)cc3)CC2)cc1>>CCCN(CCO)C(=O)Nc1ccc(N2CCN(c3ccc(OC)cc3)CC2)cc1 -US20100152160A1,2,COc1cc2c(cc1Cl)N(C)CC(C(=O)O)O2.C[C@@H]1CN(Cc2ccc(F)cc2)CCN1>>COc1cc2c(cc1Cl)N(C)CC(C(=O)N1CCN(Cc3ccc(F)cc3)C[C@H]1C)O2 -US20150232481A1,7,C=CCc1cc(C)ccc1C(=O)OC>>C=CCc1cc(C)ccc1CO -US04885027,2,CCOC(=O)CNC.O=S(=O)(Cl)Cc1cccc(C(F)(F)F)c1>>CCOC(=O)CN(C)S(=O)(=O)Cc1cccc(C(F)(F)F)c1 -US06162809,1,Cc1c(Cl)cc[n+]([O-])c1C.OCCS>>Cc1c(SCCO)cc[n+]([O-])c1C -US04659734,1,C=CCN1CCNCC1.Cc1csc2c(C(=O)O)c(=O)c3cc(F)c(Cl)cc3n12>>C=CCN1CCN(c2cc3c(=O)c(C(=O)O)c4scc(C)n4c3cc2Cl)CC1 -US20110245242A1,7,COc1cc(N2CCCC2=O)cc([N+](=O)[O-])c1>>COc1cc(N)cc(N2CCCC2=O)c1 -US20130040930A1,2,CS(=O)(=O)Nc1ccc(C(=O)O)cc1.Cc1ccc(C(=O)C2CCNCC2)cc1>>Cc1ccc(C(=O)C2CCN(C(=O)c3ccc(NS(C)(=O)=O)cc3)CC2)cc1 -US20060047123A1,2,CC(=O)SCC(=O)NCCCCCN.O=C=Nc1ccccc1>>CC(=O)SCC(=O)NCCCCCNC(=O)Nc1ccccc1 -US20090005363A1,1,COC(=O)c1ccc(Cl)nc1.Cc1ccc(N)cn1>>COC(=O)c1ccc(Nc2ccc(C)nc2)nc1 -US20150141406A1,1,CC1(C)OB(c2ccc(O)cc2)OC1(C)C.CCOC(=O)CBr>>CCOC(=O)COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1 -US05750520,4,COCC(=O)NCCc1ccccc1>>COCC1=NCCc2ccccc21 -US06429207B1,2,C[C@H]1CC[C@H](N)CC1.O=C(O)c1cccc(Br)n1>>C[C@@H]1CC[C@@H](NC(=O)c2cccc(Br)n2)CC1 -US03992535,2,COC(=O)C1=C(O)c2ccc3ccccc3c2S(=O)(=O)N1C.Nc1nc2ccccc2s1>>CN1C(C(=O)Nc2nc3ccccc3s2)=C(O)c2ccc3ccccc3c2S1(=O)=O -US20140350003A1,1,CO.Clc1ncc(Br)cn1>>COc1ncc(Br)cn1 -US20050148624A1,2,CCC(O)CNCc1ccc(S(C)(=O)=O)cc1.O=C(O)c1ccc(Cl)cc1C(=O)c1ccc(Br)cc1>>CCC(O)CN(Cc1ccc(S(C)(=O)=O)cc1)C(=O)c1ccc(Cl)cc1C(=O)c1ccc(Br)cc1 -US20140163012A1,1,FCCN1CCc2c(sc3cc(Br)ccc23)C1.O=c1cc(OCc2ccc(F)cn2)cc[nH]1>>O=c1cc(OCc2ccc(F)cn2)ccn1-c1ccc2c3c(sc2c1)CN(CCF)CC3 -US20120128630A1,1,COC(=O)[C@@H](O)c1ccccc1.Cc1ccc(N2C(=O)C(O)=C(C(=O)c3ccc(C(C)C)cc3)C2c2ccc(OC(F)(F)F)cc2)nn1>>COC(=O)[C@H](OC1=C(C(=O)c2ccc(C(C)C)cc2)[C@H](c2ccc(OC(F)(F)F)cc2)N(c2ccc(C)nn2)C1=O)c1ccccc1 -US20090036495A1,2,CO.O=C(O)c1cc(F)cnc1Cl>>COC(=O)c1cc(F)cnc1Cl -US20040097733A1,6,CCCCCCOc1cc2c(cc1N(CC)c1ccc(C(=O)OCC)cc1)C(C)=CCC2(C)C>>CCCCCCOc1cc2c(cc1N(CC)c1ccc(C(=O)O)cc1)C(C)=CCC2(C)C -US20120283254A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>Cc1ccc(S(=O)(=O)N[C@@H]2CC[C@@H](CCN3CCCCC3c3coc4cccc-4c3)CC2)cc1 -US20150072976A1,6,COC(=O)c1ccc(-c2nc(COc3ccc(C)cc3)c(C)o2)cc1>>Cc1ccc(OCc2nc(-c3ccc(C(=O)O)cc3)oc2C)cc1 -US20030207865A1,7,O=C(NC1(C(=O)O)CCCCC1)OCc1ccccc1>>O=C(NC1(CO)CCCCC1)OCc1ccccc1 -US08492405B2,2,CC(=O)Cl.Cc1sc2cc(C3=NCC4(CCNCC4)S3)[nH]c2c1N(C)S(=O)(=O)c1cccs1>>CC(=O)N1CCC2(CC1)CN=C(c1cc3sc(C)c(N(C)S(=O)(=O)c4cccs4)c3[nH]1)S2 -US20100137338A1,6,Cn1nccc1-c1ccc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)cc1F>>Cn1nccc1-c1ccc(C(=O)N[C@H](CN)Cc2ccccc2C(F)(F)F)cc1F -US06087392,2,CCOC(=O)C1(N)CCOCC1.O=S(=O)(Cl)c1ccc(Oc2ccc(F)cc2)cc1>>CCOC(=O)C1(NS(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2)CCOCC1 -US20090247526A1,1,N#Cc1c(Cl)cncc1Cl.Oc1cc(Nc2nc(CCc3ccccc3)cs2)ncc1Br>>N#Cc1c(Cl)cncc1Oc1cc(Nc2nc(CCc3ccccc3)cs2)ncc1Br -US20040121965A1,6,C=CCC(/C=C(\C)C(=O)OCC)N(C)C(=O)OC(C)(C)C>>C=CC[C@@H](/C=C(\C)C(=O)OCC)NC -US05028603,2,Cc1nnc2n1-c1sc(C(C)O)cc1C(c1ccccc1Cl)=NC2.O=C(Cl)c1ccccc1>>Cc1nnc2n1-c1sc(C(C)OC(=O)c3ccccc3)cc1C(c1ccccc1Cl)=NC2 -US20040242884A1,1,CNCC(O)c1cccnc1.COCCOCc1c(CCl)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12>>COCCOCc1c(CN(C)CC(O)c2cccnc2)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12 -US20050065098A1,2,CCCCCC(=O)Cl.COc1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1>>CCCCCC(=O)OC[C@H]1O[C@@H](Oc2ccccc2Cc2ccc(OC)cc2)[C@H](O)[C@@H](O)[C@@H]1O -US20090036469A1,3,CC1(C)OB(c2ccc3c(c2)CC(C(=O)O)O3)OC1(C)C.COc1nc(Cl)cc(NCCc2ccc(Cl)cc2Cl)n1>>COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2ccc3c(c2)CC(C(=O)O)O3)n1 -US20120225846A1,6,COC(=O)/C=C/c1cnc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1>>O=C(O)/C=C/c1cnc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1 -US20070167437A1,2,CCOc1ncccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)Cl.O=C1CNCCN1>>CCOc1ncccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCNCC1=O -US20100041891A1,6,CCOC(=O)c1cc2c(F)ccc(Br)c2s1>>O=C(O)c1cc2c(F)ccc(Br)c2s1 -US20060148858A1,7,CCOC(=O)c1cn(-c2ccc(C(F)(F)F)cn2)nc1C1CCCCC1>>OCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C1CCCCC1 -US08178522B2,2,CC(C)N.Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)O>>Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)NC(C)C -US20120172333A1,3,N#Cc1c(O)c2c(ccn2-c2ccc(Br)cc2)[nH]c1=O.OB(O)c1ccc(F)nc1>>N#Cc1c(O)c2c(ccn2-c2ccc(-c3ccc(F)nc3)cc2)[nH]c1=O -US20070244125A1,1,CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1.OCc1ccccc1>>CC(C)N1CCN(C(=O)c2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3Cc2ccccc2)CC1 -US20120289474A1,4,CCOc1cc([C@H]2CSCC[C@H]2NC(=O)c2ccc(C(=O)OC)cc2)ccc1OC>>CCOc1cc2c(cc1OC)C(c1ccc(C(=O)OC)cc1)=N[C@@H]1CCSC[C@H]21 -US20090270450A1,3,CCOc1cc([N+](=O)[O-])ccc1Br.OB(O)c1ccncc1>>CCOc1cc([N+](=O)[O-])ccc1-c1ccncc1 -US20080261975A1,3,CCCC[Sn](/C=C/C(C)(C)O)(CCCC)CCCC.CN(C)CCCOc1ccc(C(=O)Cl)cc1>>CN(C)CCCOc1ccc(C(=O)/C=C/C(C)(C)O)cc1 -US04988694,6,CC(=O)Nc1ccc(C(C)=O)nc1Cl>>CC(=O)c1ccc(N)c(Cl)n1 -US20100256134A1,2,CCS(N)(=O)=O.Cc1ccc(F)c(Nc2c(C(=O)N3CCC(c4ccc5ccccc5c4)CC3)cnc3c(C(=O)O)cnn23)c1>>CCS(=O)(=O)NC(=O)c1cnn2c(Nc3cc(C)ccc3F)c(C(=O)N3CCC(c4ccc5ccccc5c4)CC3)cnc12 -US05990105,1,C1CNCCN1.Nc1ccc(S(=O)(=O)c2cc(Br)nc(Br)c2)cc1>>Nc1ccc(S(=O)(=O)c2cc(Br)nc(N3CCNCC3)c2)cc1 -US04375476,7,Cc1ccc(C#N)c(C)c1C(=O)O>>Cc1ccc(C#N)c(C)c1CO -US07615634B2,6,COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CN(C(=O)OC(C)(C)C)C2)nc1N>>COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CNC2)nc1N -US20090099355A1,1,CC1(C)OB(c2ccc(Br)cc2)OC1(C)C.COP(OC)OC>>COP(=O)(OC)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1 -US05480899,7,COc1ccc(N2C[C@](C)(COC(=O)c3ccc([N+](=O)[O-])cc3)OC2=O)cc1>>COc1ccc(N2C[C@](C)(CO)OC2=O)cc1 -US20140350034A1,2,Nc1c(Cl)ncnc1Cl.O=C(Cl)Cc1c(Cl)cccc1Cl>>O=C(Cc1c(Cl)cccc1Cl)Nc1c(Cl)ncnc1Cl -US20090275750A1,1,N#Cc1ccccc1CBr.O=c1cc(Cl)[nH]c(=O)[nH]1>>N#Cc1ccccc1Cn1c(Cl)cc(=O)[nH]c1=O -US20110003820A1,2,CC1NCCn2nccc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2ccnn2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US08975254B2,2,CC(=O)c1cc(C(=O)O)[nH]n1.C[C@@H](CN)n1ccc(-c2cc(F)c(C#N)c(F)c2)n1>>CC(=O)c1cc(C(=O)NC[C@H](C)n2ccc(-c3cc(F)c(C#N)c(F)c3)n2)[nH]n1 -US20120046267A1,3,CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(Cl)cc34)cn2)CC1.CC1(C)OB(c2cccc3cnncc23)OC1(C)C>>CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5cccc6cnncc56)cc34)cn2)CC1 -US20070060567A1,7,COC(=O)c1cc(OC)c2cc[nH]c2c1>>COC(=O)c1cc2c(c(OC)c1)CCN2 -US20140163033A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(C(=O)O)C(F)(F)F>>CC(C)(C)OC(=O)NC(C(=O)O)C(F)(F)F -US20120277439A1,2,CC(=O)c1cccnc1N.CC(C)(C)C(=O)Cl>>CC(=O)c1cccnc1NC(=O)C(C)(C)C -US20140243347A1,3,CCOC(=O)CC1CNC(=O)c2cc(I)cn21.OB(O)c1cccc(Cl)c1>>CCOC(=O)CC1CNC(=O)c2cc(-c3cccc(Cl)c3)cn21 -US05792385,1,CCCCCCCCC(=O)O.Oc1ccccc1>>CCCCCCCCC(=O)Oc1ccccc1 -US04339457,7,CCOC(=O)c1cccc(-n2cccc2)c1>>OCc1cccc(-n2cccc2)c1 -US04376731,2,COC(=O)Cl.NC(=O)C1CN1>>COC(=O)N1CC1C(N)=O -US08299073B2,2,COCC(=O)Cl.Nc1cc(COc2ccc([N+](=O)[O-])c3ccccc23)ccn1>>COCC(=O)Nc1cc(COc2ccc([N+](=O)[O-])c3ccccc23)ccn1 -US20080076774A1,6,CCN(CC)CCOc1cccc(N2CCN(C(=O)OC(C)(C)C)CC2)c1C>>CCN(CC)CCOc1cccc(N2CCNCC2)c1C -US06521643B1,7,COc1ccnc(-c2cc([N+](=O)[O-])ccc2C)c1>>COc1ccnc(-c2cc(N)ccc2C)c1 -US06664260B2,1,ClCc1ccncc1.OCCn1cnc2c(Oc3ccccc3)nc3ccccc3c21>>c1ccc(Oc2nc3ccccc3c3c2ncn3CCOCc2ccncc2)cc1 -US04987235,6,COc1cc2c(cc1OC)CN(Cc1ccccc1)C2>>COc1cc2c(cc1OC)CNC2 -US20110045027A1,7,O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)C(F)(F)F -US20060247210A1,1,CNC.Cc1[nH]nc(N)c1-c1nc2cc(F)c(CO)cc2s1>>Cc1[nH]nc(N)c1-c1nc2cc(F)c(CN(C)C)cc2s1 -US20060100262A1,6,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCN(CCN(C)C)Cc1ccoc1-3>>CN(C)CCN1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2occc2C1 -US06251897B1,2,COC(=O)Cl.COc1ccc(C(O)CCN)cc1OC>>COC(=O)NCCC(O)c1ccc(OC)c(OC)c1 -US20030166725A1,1,COC(=O)Cc1cc(Br)c(Oc2cc(C(C)C)c(OC)cc2C(Cl)c2ccccc2C)c(Br)c1.Oc1ccc(F)cc1F>>COC(=O)Cc1cc(Br)c(Oc2cc(C(C)C)c(OC)cc2C(Oc2ccc(F)cc2F)c2ccccc2C)c(Br)c1 -US07803822B2,2,CCNC(=O)c1ccc(-n2nnc(C(=O)OC)c2OCC)cc1.NC1CC1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2OCC)cc1 -US07863332B2,8,CCCCOc1cc(CO)ccc1I>>CCCCOc1cc(C=O)ccc1I -US20070123534A1,2,Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc(N)cc3F)c12.O=C(O)c1cccn(-c2ccc(F)cc2)c1=O>>Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12 -US05670498,6,CCn1c(=O)c2c(nc(/C=C/c3ccc(C(=O)OC)cc3OC)n2C)n(CC)c1=O>>CCn1c(=O)c2c(nc(/C=C/c3ccc(C(=O)O)cc3OC)n2C)n(CC)c1=O -US20100048636A1,1,CC(C)(C)OC(=O)N[C@H](COS(C)(=O)=O)CC1(F)CCCCC1.CN>>CNC[C@H](CC1(F)CCCCC1)NC(=O)OC(C)(C)C -US20090069282A1,1,C1CCNC1.Cc1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCOS(C)(=O)=O>>Cc1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCN1CCCC1 -US20070249670A1,2,COC(=O)C1(N)CCCCC1.Nc1cc(-c2ccc(F)c(F)c2)sc1C(=O)O>>COC(=O)C1(NC(=O)c2sc(-c3ccc(F)c(F)c3)cc2N)CCCCC1 -US20090054428A1,9,Cc1nc(Cl)c(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1>>Cc1ncc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1 -US06951879B2,1,CS(=O)(=O)OCCCC#Cc1ccc2c(-c3ccc(Cl)cc3)nsc2c1.OCCNCCO>>OCCN(CCO)CCCC#Cc1ccc2c(-c3ccc(Cl)cc3)nsc2c1 -US05959107,1,N#Cc1ccc(F)c(Cl)c1.Sc1cccc2cnccc12>>N#Cc1ccc(Sc2cccc3cnccc23)c(Cl)c1 -US04250085,6,C[C@H](NC(=O)CN(C)C(=O)OCc1ccccc1)C(=O)N[C@@H](C)P(=O)(O)O>>CNCC(=O)N[C@@H](C)C(=O)N[C@@H](C)P(=O)(O)O -US20150087617A1,7,c1ccc2[nH]ccc2c1>>c1ccc2c(c1)CCN2 -US20120184587A1,6,COc1c(C#N)cc(C(=O)N2CS(=O)(=O)c3ccccc32)cc1SC>>CSc1cc(C(=O)N2CS(=O)(=O)c3ccccc32)cc(C#N)c1O -US20030060471A1,2,COC(=O)c1cnccn1.N#Cc1cc(N)n(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1>>N#Cc1cc(NC(=O)c2cnccn2)n(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1 -US20130317015A1,7,COC(=O)[C@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)NC(=O)[C@@H]1Cc2cc([N+](=O)[O-])c(O)cc2CN1C(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)NC(=O)[C@@H]1Cc2cc(N)c(O)cc2CN1C(=O)OC(C)(C)C -US20100179128A1,1,C=CCn1c(Cl)nc2[nH]c(=O)[nH]c(=O)c21.FC(F)(F)CI>>C=CCn1c(Cl)nc2c1c(=O)[nH]c(=O)n2CC(F)(F)F -US20140100373A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=Cc1c[nH]cn1>>Cc1ccc(S(=O)(=O)n2cnc(C=O)c2)cc1 -US20060094754A1,1,C1CCCNCC1.Cc1nc2ccc(Br)cc2c(-c2ccc(F)cc2)c1C(=O)C(F)(F)F>>Cc1nc2ccc(N3CCCCCC3)cc2c(-c2ccc(F)cc2)c1C(=O)C(F)(F)F -US06521627B1,1,CC(Br)c1ncnc(Cl)c1I.NCCc1ccc(OC(F)(F)F)cc1>>CC(Br)c1ncnc(NCCc2ccc(OC(F)(F)F)cc2)c1I -US20090076004A1,3,CC(C)(C)c1ccc(B(O)O)cc1.CCOC(=O)c1c(C=O)c2cc(Br)ccc2n1-c1ccc(OC(C)C)cc1>>CCOC(=O)c1c(C=O)c2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1 -US07863305B2,9,Brc1cccc2[nH]ncc12.[C-]#N>>N#Cc1cccc2[nH]ncc12 -US20050197350A1,1,O=C(N[C@@H]1CC[C@H](Nc2ccc3ccccc3n2)CC1)c1cccnc1Cl.Oc1ccccc1Br>>O=C(N[C@@H]1CC[C@H](Nc2ccc3ccccc3n2)CC1)c1cccnc1Oc1ccccc1Br -US20150266874A1,2,CN1CCC(N)CC1.C[Si](C)(C)CCOCn1cc(C(=O)O)c(-c2nc3c(s2)CCCC3)n1>>CN1CCC(NC(=O)c2cn(COCC[Si](C)(C)C)nc2-c2nc3c(s2)CCCC3)CC1 -US20100029736A1,1,CC(C)(C)OC(=O)CBr.Cc1ccc2nc(S)[nH]c2c1>>Cc1ccc2nc(SCC(=O)OC(C)(C)C)[nH]c2c1 -US08227500B2,9,N.N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccccc1>>N#Cc1cn(-c2ccc(C(N)=O)cc2)cc1-c1ccccc1 -US20110201657A1,1,CC(C)(C)OC(=O)c1cccc(N)c1.COC(=O)c1cccc(C=O)c1[N+](=O)[O-]>>COC(=O)c1cccc(/C=N/c2cccc(C(=O)OC(C)(C)C)c2)c1[N+](=O)[O-] -US07235548B2,2,CC(=O)OC(C)=O.Cc1cccc(N)c1>>CC(=O)Nc1cccc(C)c1 -US20150031920A1,7,CC(=O)c1c(Cl)ccc(F)c1Cl>>C[C@H](O)c1c(Cl)ccc(F)c1Cl -US20150258074A1,2,CC(=O)Cl.COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(N)c12>>COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(NC(C)=O)c12 -US20120115862A1,6,COc1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2>>O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(O)cc21 -US07368578B2,1,CC(C)(C)c1nc(CCl)co1.CCOP(OCC)OCC>>CCOP(=O)(Cc1coc(C(C)(C)C)n1)OCC -US08822430B2,3,CC(C)(C)OC(=O)NCC(=O)c1ccc(Br)cc1.COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(C(=O)CNC(=O)OC(C)(C)C)cc3)cc2)[nH]1)C(C)C -US05994378,1,CC(C)(C)c1csc(-c2cc3cc(CCl)ccc3o2)n1.COc1ccc2[nH]nc(C(=O)O)c2c1>>COc1ccc2c(c1)c(C(=O)O)nn2Cc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1 -US07495007B2,1,CI.Cc1ccccc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)ccc12>>Cc1ccccc1C1N(C)C(=O)CC(c2cccc(Cl)c2)C12C(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)ccc12 -US20070117866A1,7,COC(=O)[C@H](Cc1cccc(OC(=O)C(C)(C)C)c1)OC(C)C>>COC(=O)[C@H](Cc1cccc(O)c1)OC(C)C -US08952169B2,1,CC(C)(C)OC(=O)c1cc(Cl)c(F)cc1F.O[C@H]1C[C@@H]2CC[C@H]1C2>>CC(C)(C)OC(=O)c1cc(Cl)c(O[C@H]2C[C@@H]3CC[C@H]2C3)cc1F -US05371100,1,C[C@H](O)[C@@]1(c2ccc(F)cc2F)CO1.c1cnc2nc[nH]c2c1>>C[C@@H](n1cnc2ncccc21)[C@@]1(c2ccc(F)cc2F)CO1 -US05225105,6,CCOC(=O)C(F)C(C)CC>>CCC(C)C(F)C(=O)O -US20150152113A1,2,COc1cc(OC)nc(C2CCN(c3cnnc(NN)c3Cl)CC2)n1.O=C(O)CC1CC1>>COc1cc(OC)nc(C2CCN(c3cnnc(NNC(=O)CC4CC4)c3Cl)CC2)n1 -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3cc(C)c(OCOC)c(C)c3)cc2)cc1)Oc1ccccc1>>COCOc1c(C)cc(-c2ccc(C(=O)NCCOc3ccc(CC(Oc4ccccc4)C(=O)O)cc3)cc2)cc1C -US20120264735A1,6,CCOc1cnc(-c2cccc(C(C)c3nn(-c4cnn(CCOCc5ccccc5)c4)ccc3=O)c2)nc1>>CCOc1cnc(-c2cccc(C(C)c3nn(-c4cnn(CCO)c4)ccc3=O)c2)nc1 -US04255575,1,COC(=O)c1cc(C(=O)CBr)ccc1O.Cc1ccccc1N1CCNCC1>>COC(=O)c1cc(C(=O)CN2CCN(c3ccccc3C)CC2)ccc1O -US08093239B2,6,CC(C)(C)OC(=O)N1CCN(C2CCN(c3ccc([N+](=O)[O-])c(OCC(F)(F)F)c3)CC2)CC1>>O=[N+]([O-])c1ccc(N2CCC(N3CCNCC3)CC2)cc1OCC(F)(F)F -US20040038239A1,7,COc1cccc(C(O)C[N+](=O)[O-])c1>>COc1cccc(C(O)CN)c1 -US08648068B2,9,Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3O[C@H]3CCN(C(=O)OC(C)(C)C)C3)c12.N>>Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3O[C@H]3CCN(C(=O)OC(C)(C)C)C3)c12 -US20130225524A1,3,CC(C)=C(C)B(O)O.Nc1cc(Br)cc(C(=O)O)c1>>CC(C)=C(C)c1cc(N)cc(C(=O)O)c1 -US07951806B2,3,CC1(C)OB(c2ccc(F)cc2F)OC1(C)C.COC(=O)c1cc(Br)ccc1NC(=O)COCC(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>COC(=O)c1cc(-c2ccc(F)cc2F)ccc1NC(=O)COCC(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1 -US20050032786A1,1,CC(C)(C)OC(=O)CBr.O=C1NCCN1c1ccncc1>>CC(C)(C)OC(=O)CN1CCN(c2ccncc2)C1=O -US08163740B2,1,CN1CCNCC1.COc1ccccc1CNC1=Nc2ccc(NC(=O)CCl)cc2CO1>>COc1ccccc1CNC1=Nc2ccc(NC(=O)CN3CCN(C)CC3)cc2CO1 -US20140296261A1,1,CCCS(=O)(=O)Nc1ccc(F)c(N)c1F.Fc1ncccc1-c1ncnc2c1ncn2C1CCCCO1>>CCCS(=O)(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F -US20080262041A1,1,C=O.C[C@@H](c1cc(Cl)cc2ccccc12)N1CCC(C2(c3ccc(F)cc3)CCNCC2)C1=O>>C[C@@H](c1cc(Cl)cc2ccccc12)N1CCC(C2(c3ccc(F)cc3)CCN(C)CC2)C1=O -US20100105700A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC=C(OS(=O)(=O)C(F)(F)F)[C@@]3(C)CC[C@@H]12>>CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC=C(c4ccccn4)[C@@]3(C)CC[C@@H]12 -US20140121368A1,3,C=O.O=C(NCCSc1ccc(OC(F)(F)F)cc1)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCSc2ccc(OC(F)(F)F)cc2C1 -US08883782B2,1,FC1(F)CCNCC1.NC1=N[C@@]2(CO1)c1cc(-c3cccnc3F)ccc1Oc1cnc(Cl)cc12>>NC1=N[C@@]2(CO1)c1cc(-c3cccnc3F)ccc1Oc1cnc(N3CCC(F)(F)CC3)cc12 -US20130178460A1,2,Cc1cc(C)nc(N)c1.O=C(O)c1csc2cnc(Cl)nc12>>Cc1cc(C)nc(NC(=O)c2csc3cnc(Cl)nc23)c1 -US20090030003A1,1,CC(C)n1ncc2c(=O)[nH]c([C@@H]3CNC[C@H]3C)nc21.O=Cc1ccnc2nccnc12>>CC(C)n1ncc2c(=O)[nH]c([C@@H]3CN(Cc4ccnc5nccnc45)C[C@H]3C)nc21 -US06953793B2,6,CC(C)(C)OC(=O)N1CCC(N2C(=O)Cc3cc(Cl)ccc32)CC1>>O=C1Cc2cc(Cl)ccc2N1C1CCNCC1 -US20050277670A1,1,BrCc1ccsc1.CC(=O)Nc1ccc(NC2CCN([C@H](C)CCNC(=O)c3c(C)ncnc3C)CC2)cn1>>CC(=O)Nc1ccc(N(Cc2ccsc2)C2CCN([C@H](C)CCNC(=O)c3c(C)ncnc3C)CC2)cn1 -US20110257151A1,3,CC(C)(C)c1ccc(B(O)O)cc1.COC(=O)c1cc(Cl)cc2c1NC(c1cccc(Br)c1)C(C)(C)C2>>COC(=O)c1cc(Cl)cc2c1NC(c1cccc(-c3ccc(C(C)(C)C)cc3)c1)C(C)(C)C2 -US20120302566A1,1,COC(=O)C[C@@H]1COc2cc(O)ccc21.O[C@H]1CCc2c(OC(F)(F)F)cccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(OC(F)(F)F)cccc43)ccc21 -US07572809B2,1,COc1cc2cc(Nc3cc(C)[nH]n3)nc(Cl)c2cc1C(=O)N(C)C.OC1CCC1>>COc1cc2cc(Nc3cc(C)[nH]n3)nc(OC3CCC3)c2cc1C(=O)N(C)C -US20090143354A1,1,N[C@H]1CCNC1.O=C(CCC1CCCC1)Nc1c(Cl)ccc2nc(Cl)ccc12>>N[C@H]1CCN(c2ccc3c(NC(=O)CCC4CCCC4)c(Cl)ccc3n2)C1 -US20090181878A1,1,C=COCC.COC(=O)C1CC(C)(C)CCC1O>>CCOC(C)OC1CCC(C)(C)CC1C(=O)OC -US08772533B1,2,C/C=C/C(=O)O.CC(O)CC(C)C(C)C>>CC=CC(=O)OC(C)CC(C)C(C)C -US04954525,3,CC(=O)C=CC=C(C)CCC=C(C)CCC=C(C)C.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=C(C)C=CC=C(C)CCC=C(C)CCC=C(C)C -US20040058903A1,2,Nc1ccc(CCC(=O)c2ccccn2)cc1.O=C(Cl)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(CCc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1ccccn1 -US20080119442A1,6,CC(C)(C)OP(=O)(OCCNC(=O)OCc1ccccc1)OC(C)(C)C>>CC(C)(C)OP(=O)(OCCN)OC(C)(C)C -US20110201640A1,7,Cc1cc(-c2ccccc2)cc([N+](=O)[O-])c1N>>Cc1cc(-c2ccccc2)cc(N)c1N -US04075001,2,CCCN(CCC)c1nsc(N)c1C#N.CN=C=O>>CCCN(CCC)c1nsc(NC(=O)NC)c1C#N -US09018382B2,1,CC(C)Br.COC(=O)c1cc([N+](=O)[O-])cc2[nH]ncc12>>COC(=O)c1cc([N+](=O)[O-])cc2c1cnn2C(C)C -US09073922B2,3,COc1ccc(F)cc1B(O)O.N#Cc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1Cl>>COc1ccc(F)cc1-c1c(C#N)cnc2c1ccn2S(=O)(=O)c1ccccc1 -US20150119362A1,3,COC(=O)Cc1ccc(CB2OC(C)(C)C(C)(C)O2)cc1.O=S1(=O)CCCc2nc(-c3cccc(Cl)c3)nc(OS(=O)(=O)C(F)(F)F)c21>>COC(=O)Cc1ccc(Cc2nc(-c3cccc(Cl)c3)nc3c2S(=O)(=O)CCC3)cc1 -US20110071150A1,3,C#Cc1ccccc1Cl.Cc1nc(-c2ccccc2)sc1-c1ccc(N)c(Br)c1>>Cc1nc(-c2ccccc2)sc1-c1ccc(N)c(C#Cc2ccccc2Cl)c1 -US20110118314A1,2,COc1cc(F)c(F)cc1-c1ccc(OCC2CCN(C(=O)N(C)CC(=O)O)C2)cc1.CS(N)(=O)=O>>COc1cc(F)c(F)cc1-c1ccc(OCC2CCN(C(=O)N(C)CC(=O)NS(C)(=O)=O)C2)cc1 -US20100144694A1,1,CC1(C)NN(C2C3CC4CC(C3)CC2C4)C1=O.Clc1cccc(Cl)c1CBr>>CC1(C)C(=O)N(C2C3CC4CC(C3)CC2C4)N1Cc1c(Cl)cccc1Cl -US20060160879A1,7,CCOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)c2ccc(-c3ccc(C(=O)O)cc3)cc2n1Cc1cccc(Cl)c1>>CCOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)c2ccc(-c3ccc(CO)cc3)cc2n1Cc1cccc(Cl)c1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CS(=O)(=O)c1cc(Br)ccc1-c1ccccc1>>CC(C)(C)OC(=O)COc1ccc(Cl)cc1C#Cc1ccc(-c2ccccc2)c(S(C)(=O)=O)c1 -US04902700,1,N#CCCCBr.Nc1cccc(/C=C/c2nc3ccccc3s2)c1>>N#CCCCNc1cccc(/C=C/c2nc3ccccc3s2)c1 -US20110071175A1,1,O=Cc1sccc1Cl.Sc1cccs1>>O=Cc1sccc1Sc1cccs1 -US08053440B2,6,COc1cc(OC)c2cnc(-c3cc(C)c(OCc4ccccc4)c(C)c3)cc2c1>>COc1cc(OC)c2cnc(-c3cc(C)c(O)c(C)c3)cc2c1 -US08822689B2,2,Cc1c(Br)cnc2cn(CC(C)(N)C#N)nc12.FC(F)(F)c1ccc(C(=S)Cl)cc1>>Cc1c(Br)cnc2cn(CC(C)(C#N)NC(=S)c3ccc(C(F)(F)F)cc3)nc12 -US20060142347A1,1,BrCc1cccc(I)c1.COC(=O)c1sc(-c2ccccc2)cc1NS(=O)(=O)c1cc(C)c(Cl)cc1C>>COC(=O)c1sc(-c2ccccc2)cc1N(Cc1cccc(I)c1)S(=O)(=O)c1cc(C)c(Cl)cc1C -US20130035310A1,2,O=C(O)CCn1ccc2cc(Cl)ccc21.O=S(=O)(Nc1ncns1)c1ccc(N2CCNCC2)cc1>>O=C(CCn1ccc2cc(Cl)ccc21)N1CCN(c2ccc(S(=O)(=O)Nc3ncns3)cc2)CC1 -US20130005738A1,3,CC(C)(C)OC(=O)Nc1ncc(C#C[Si](C)(C)C)s1.Cc1cn(-c2cc(NC(=O)c3ccc(C)c(I)c3)cc(C(F)(F)F)c2)cn1>>Cc1cn(-c2cc(NC(=O)c3ccc(C)c(C#Cc4cnc(NC(=O)OC(C)(C)C)s4)c3)cc(C(F)(F)F)c2)cn1 -US04348335,7,O=[N+]([O-])c1ccc(C=Cc2ccc([N+](=O)[O-])cc2S(=O)(=O)O)c(S(=O)(=O)O)c1>>Nc1ccc(C=Cc2ccc([N+](=O)[O-])cc2S(=O)(=O)O)c(S(=O)(=O)O)c1 -US06608072B1,7,Fc1ccc(-c2nc3nc(-c4ccncc4)ccc3n2-c2ccnc(NC3CCCC3)n2)cc1>>Fc1ccc(-c2nc3nc(C4CCNCC4)ccc3n2-c2ccnc(NC3CCCC3)n2)cc1 -US04231944,2,CCN.COc1cc(Cl)c(/C=C/C(C)=C(F)/C=C/C(C)=C/C(=O)O)c(Cl)c1C>>CCNC(=O)/C=C(C)/C=C/C(F)=C(C)/C=C/c1c(Cl)cc(OC)c(C)c1Cl -US06638965B2,7,O=[N+]([O-])c1ccc(CN2CCN(Cc3ccccc3)CC2)cc1>>Nc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 -US05104890,6,COc1ccc(S(=O)(=O)N(C)C)cc1>>CN(C)S(=O)(=O)c1ccc(O)cc1 -US08048909B2,4,CCOC(=O)C(C(C)=O)C(C)C(=O)c1ccccc1.[NH4+]>>CCOC(=O)c1c(C)[nH]c(-c2ccccc2)c1C -US08946427B2,2,C1CCNC1.COC1CCN(c2nc3ccc(NC(=O)c4c(C(=O)O)cnn4C)cn3n2)C1>>COC1CCN(c2nc3ccc(NC(=O)c4c(C(=O)N5CCCC5)cnn4C)cn3n2)C1 -US06159904,1,CCn1nccc1O.Cc1c(C(=O)O)ccc2c1C(Cl)C(Cl)CS2(=O)=O>>CCn1nccc1OC(=O)c1ccc2c(c1C)C(Cl)C(Cl)CS2(=O)=O -US04435406,7,Nc1cc2c(cc1[N+](=O)[O-])OCCCO2>>Nc1cc2c(cc1N)OCCCO2 -US20120142733A1,2,NC(=O)C(NC1CCC(c2c[nH]c3ccccc23)CC1)C1CCNCC1.O=C(O)/C=C/c1ccccc1F>>NC(=O)C(NC1CCC(c2c[nH]c3ccccc23)CC1)C1CCN(C(=O)/C=C/c2ccccc2F)CC1 -US06875765B2,2,CCOC(OCC)[C@@H](N)CC(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccccc1OCc1ccccc1>>CCOC(OCC)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1OCc1ccccc1 -US20150252038A1,2,CC(C)Nc1ccc(F)cc1CN1CCC(COc2cc(F)c(C(=O)O)cc2C2CC2)CC1.NS(=O)(=O)C1CC1>>CC(C)Nc1ccc(F)cc1CN1CCC(COc2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc2C2CC2)CC1 -US20060167246A1,2,COC(=O)c1cc2[nH]c(-c3ccc(OCc4ccccc4)cc3N)c(C3CCCCC3)c2s1.O=C(Cl)CCl>>COC(=O)c1cc2[nH]c(-c3ccc(OCc4ccccc4)cc3NC(=O)CCl)c(C3CCCCC3)c2s1 -US07863332B2,6,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCc2ccc(F)cc2)c1>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)O)cc2OCc2ccc(F)cc2)c1 -US06583319B1,2,CNOC.COc1ccc2cccc(C=CC(=O)O)c2c1>>COc1ccc2cccc(C=CC(=O)N(C)OC)c2c1 -US07067534B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.COc1ccc(S(=O)(=O)Cl)cc1OC>>COc1ccc(S(=O)(=O)NCCCN2CCC(c3cccc(NC(=O)C(C)C)c3)CC2)cc1OC -US07544835B2,2,CCOc1ccc(CC(C(=O)OC)C(=O)OC)cc1CO.O=C=Nc1ccc(Cl)cc1Cl>>CCOc1ccc(CC(C(=O)OC)C(=O)OC)cc1COC(=O)Nc1ccc(Cl)cc1Cl -US06610694B1,1,CCOC(=O)C(C)(C)NC(=O)c1nnc2ccc(Cl)nn12.NCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>CCOC(=O)C(C)(C)NC(=O)c1nnc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn12 -US20110257151A1,1,C1COCCN1.COC(=O)c1cc(Cl)cc2c1NC(c1cccc(Br)c1)C(C)(C)C2>>COC(=O)c1cc(Cl)cc2c1NC(c1cccc(N3CCOCC3)c1)C(C)(C)C2 -US04925865,7,O=C(C=Cc1ccc(Cl)cc1)C1(Cl)CC1>>O=C(CCc1ccc(Cl)cc1)C1(Cl)CC1 -US05492918,2,NC1CCN(Cc2ccccc2)CC1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)NC1CCN(Cc2ccccc2)CC1 -US07115624B1,6,CC(C)(C)OC(=O)c1c(OCc2ccccc2)sc2c1C(N=C=O)C(CN1C(=O)c3ccccc3C1=O)N(C(=O)OC(C)(C)C)C2>>CC(C)(C)OC(=O)c1c(OCc2ccccc2)sc2c1C(N=C=O)C(CN1C(=O)c3ccccc3C1=O)NC2 -US20110086853A1,6,CC(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2CC1CCOCC1>>CC(C)(C)c1nc2cc(N)ccc2n1CC1CCOCC1 -US20110150833A1,6,COc1ccc2c(c1)CC(C(=O)Nc1ccc(-c3cn[nH]c3)cc1OCCN(C)Cc1ccccc1)CO2>>CNCCOc1cc(-c2cn[nH]c2)ccc1NC(=O)C1COc2ccc(OC)cc2C1 -US20130338173A1,1,CC(C)=O.CC1(C)O[C@@H]2[C@H](O1)[C@@H](CN)C[C@H]2n1ccc2c(N)ncnc21>>CC(C)NC[C@H]1C[C@@H](n2ccc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@H]12 -US20150246915A1,3,COc1ccc([N+](=O)[O-])nc1Br.OB(O)c1ccc2c(c1)OCCO2>>COc1ccc([N+](=O)[O-])nc1-c1ccc2c(c1)OCCO2 -US20070049632A1,1,Cc1noc(C)c1CCl.Cn1[nH]c(=O)c2c1[C@]1(C)CC[C@H]2C1(C)C>>Cc1noc(C)c1Cn1c(=O)c2c(n1C)[C@]1(C)CC[C@H]2C1(C)C -US20130072470A1,1,C[C@@H]1C[C@H](C=O)C[C@@H]1c1cnc2cnc3[nH]ccc3n12.N#CC1CNC1>>C[C@@H]1C[C@@H](CN2CC(C#N)C2)C[C@@H]1c1cnc2cnc3[nH]ccc3n12 -US08436008B2,1,CC1(C)OB(c2c[nH]c(C(=O)OCc3ccccc3)c2)OC1(C)C.CI>>Cn1cc(B2OC(C)(C)C(C)(C)O2)cc1C(=O)OCc1ccccc1 -US20150011551A1,7,COC(=O)c1ccc2ncc(NS(=O)(=O)c3cc(OC)ccc3OC)cc2c1>>COc1ccc(OC)c(S(=O)(=O)Nc2cnc3ccc(CO)cc3c2)c1 -US04914109,2,NC1=NCCS1.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>O=C(Cn1c(-c2ccc(Cl)cc2)nc2cccnc21)NC1=NCCS1 -US05773624,2,CCON=C(C(=O)OC)c1nsc(N)n1.O=CO>>CCON=C(C(=O)OC)c1nsc(NC=O)n1 -US20070299076A1,2,COC(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1N.O=C(O)CCC(F)(F)CCl>>COC(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1NC(=O)CCC(F)(F)CCl -US20130053563A1,2,CC(Cl)OC(=O)Cl.CCC[C@@H](C)O>>CCC[C@@H](C)OC(=O)OC(C)Cl -US20040102437A1,2,CN.O=C(O)C(c1ccccc1)N1CCCC(Nc2ccc3[nH]ncc3c2)C1>>CNC(=O)C(c1ccccc1)N1CCCC(Nc2ccc3[nH]ncc3c2)C1 -US04616086,2,CCCCOC(=O)c1ccc(N2CCNCC2)cc1.CS(=O)(=O)Cl>>CCCCOC(=O)c1ccc(N2CCN(S(C)(=O)=O)CC2)cc1 -US20090023727A1,2,COCCOC1CCNCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F>>COCCOC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 -US04810713,1,COc1cc(C(C)=O)ccc1OCCCCl.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>COc1cc(C(C)=O)ccc1OCCCN1CCC(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US20040152715A1,2,N[C@H]1CC[C@H](O)CC1.O=C(O)CCc1ccccc1>>O=C(CCc1ccccc1)N[C@@H]1CC[C@@H](O)CC1 -US08586571B2,2,CC(C)(C)c1ccccc1OC1CNC1.O=C(Cl)c1ccccn1>>CC(C)(C)c1ccccc1OC1CN(C(=O)c2ccccn2)C1 -US06359134B1,2,CC(C)N(Cc1ccc(C(=O)N2CCNCC2)cc1)C(C)C.O=S(=O)(Cl)c1ccc2cc(Br)ccc2c1>>CC(C)N(Cc1ccc(C(=O)N2CCN(S(=O)(=O)c3ccc4cc(Br)ccc4c3)CC2)cc1)C(C)C -US20080004297A1,1,CI.COc1ccc(Nc2nc(C)nc3ccccc23)cc1OC>>COc1ccc(N(C)c2nc(C)nc3ccccc23)cc1OC -US20070088044A1,1,C1CCNCC1.Fc1cccc(COc2ccc(Nc3ncnc4cc(OCCCl)cc(OC5CCOC5)c34)cc2Cl)c1>>Fc1cccc(COc2ccc(Nc3ncnc4cc(OCCN5CCCCC5)cc(OC5CCOC5)c34)cc2Cl)c1 -US20090264415A2,2,Nc1nc(NC2CCNCC2)c2nc(-c3ccc(F)cc3)ccc2n1.O=C(Cl)COc1ccccc1>>Nc1nc(NC2CCN(C(=O)COc3ccccc3)CC2)c2nc(-c3ccc(F)cc3)ccc2n1 -US20150005281A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1CNc1nc(Cl)ncc1Cl>>Clc1ncc(Cl)c(NC[C@H]2CCCN2)n1 -US04863904,2,CC(C)C[C@@H](C=NNC(N)=O)NC(=O)[C@@H](N)Cc1c[nH]cn1.O=C(Cc1cccc2ccccc12)NCC(Cc1ccccc1)C(=O)O>>CC(C)C[C@@H](C=NNC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)C(CNC(=O)Cc1cccc2ccccc12)Cc1ccccc1 -US08796256B2,1,CC(C)(C)OC(=O)N1C[C@@H](O)[C@H](F)C1.O=C1NC(=O)C(=Cc2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)S1>>CC(C)(C)OC(=O)N1C[C@H](F)[C@H](N2C(=O)SC(=Cc3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)C1 -US20060160790A1,1,Nc1ccc(I)cc1.O=C1COCCN1>>Nc1ccc(N2CCOCC2=O)cc1 -US20120263708A1,3,Brc1ccc2ncc(N3CCOCC3)nc2c1.O=[N+]([O-])c1cc(B(O)O)ccc1F>>O=[N+]([O-])c1cc(-c2ccc3ncc(N4CCOCC4)nc3c2)ccc1F -US06121470,2,CCCCCCCCCCCC(=O)Cl.O=C([O-])CNCCC(=O)O>>CCCCCCCCCCCC(=O)N(CCC(=O)O)CC(=O)[O-] -US20110144081A1,2,CN(C(=O)Oc1ccc(F)cc1)[C@@H]1CNC[C@H]1c1ccc(Cl)cc1.O=C(O)C1CCN(c2ccc(Cl)nn2)CC1>>CN(C(=O)Oc1ccc(F)cc1)[C@@H]1CN(C(=O)C2CCN(c3ccc(Cl)nn3)CC2)C[C@H]1c1ccc(Cl)cc1 -US20150111857A1,1,CC(C)(C)OC(=O)N1CCO[C@H](COS(C)(=O)=O)C1.O=[N+]([O-])c1cn[nH]c1>>CC(C)(C)OC(=O)N1CCO[C@H](Cn2cc([N+](=O)[O-])cn2)C1 -US07709471B2,1,CC(C)N1CCC(=O)N(C)c2cnc(Cl)nc21.Nc1ccc(C(=O)NCCN2CCOCC2)cc1Cl>>CC(C)N1CCC(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCN4CCOCC4)cc3Cl)nc21 -US09150508B2,2,CCCCc1ccc(NCC(C)C)c(C)c1.Cc1cc(S(=O)(=O)Cl)ccc1OCC(=O)O>>CCCCc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(OCC(=O)O)c(C)c2)c(C)c1 -US20090270388A1,2,Nc1nc2ccccc2c2nccn12.O=C(O)c1cccnc1>>O=C(Nc1nc2ccccc2c2nccn12)c1cccnc1 -US20050222151A1,1,C1CCNCC1.O=Cc1cccc(Br)n1>>Brc1cccc(CN2CCCCC2)n1 -US20090202540A1,1,CC(N)c1ccccc1.OCCCCl>>CC(NCCCO)c1ccccc1 -US04050921,8,N#Cc1ccc(CSc2cccc[n+]2[O-])cc1.O=C(OO)c1cccc(Cl)c1>>N#Cc1ccc(CS(=O)c2cccc[n+]2[O-])cc1 -US20070191395A1,6,CC(C)c1c[nH]c(COCc2ccccc2)n1>>CC(C)c1c[nH]c(CO)n1 -US08921388B2,2,COC(=O)c1nc(Cc2ccccc2Br)[nH]c(=O)c1O.NCc1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)c1nc(Cc2ccccc2Br)[nH]c(=O)c1O -US06608087B1,2,CCN.CCOC(=O)c1[nH]nc(-c2cnc(-c3ccccc3)s2)c1Cl>>CCNC(=O)c1[nH]nc(-c2cnc(-c3ccccc3)s2)c1Cl -US06472396B1,1,COc1ccc(CCCC2(Br)C(=O)NC(=O)NC2=O)cc1.OCCN1CCNCC1>>COc1ccc(CCCC2(N3CCN(CCO)CC3)C(=O)NC(=O)NC2=O)cc1 -US20110207777A1,7,CCCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)cc(F)c3[N+](=O)[O-])CC2)CC1>>CCCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)cc(F)c3N)CC2)CC1 -US05739401,1,CC(=O)c1ccc(Cl)cc1.NC=O>>CC(NC=O)c1ccc(Cl)cc1 -US07947816B2,2,C[C@@H](O)C[C@@H](C)O.O=C(O)c1ccccc1>>C[C@@H](O)C[C@H](C)OC(=O)c1ccccc1 -US20130059845A1,6,CCOC(=O)c1c(-c2cc(F)ccc2Cl)nc2ccncn12>>O=C(O)c1c(-c2cc(F)ccc2Cl)nc2ccncn12 -US06375922B1,8,CCCCCCC(C)O>>CCCCCCC(C)=O -US20080015202A1,2,CC(=O)Nc1nc(CCc2ccc(CCN)cc2)cs1.C[Si](C)(C)N=C=O>>CC(=O)Nc1nc(CCc2ccc(CCNC(N)=O)cc2)cs1 -US20060173214A1,9,COc1ccc(CC(C)=O)cc1S(N)(=O)=O.NO>>COc1ccc(CC(C)=NO)cc1S(N)(=O)=O -US04258047,1,CN1CCC(O)CC1.O=C(O)Cc1cnn(-c2ccccc2)c1-c1ccc(Cl)cc1>>CN1CCC(OC(=O)Cc2cnn(-c3ccccc3)c2-c2ccc(Cl)cc2)CC1 -US05760054,1,Cc1ccc2c(c1)oc(=O)n2C1CCNCC1.O=C1c2cc([N+](=O)[O-])ccc2S(=O)(=O)N1CCCCBr>>Cc1ccc2c(c1)oc(=O)n2C1CCN(CCCCN2C(=O)c3cc([N+](=O)[O-])ccc3S2(=O)=O)CC1 -US04002746,8,CCC[C@]12CC[C@@H]3C4=C(CC[C@H]3[C@@H]1CC[C@@H]2O)CC(OC)=CC4>>CCC[C@]12CC[C@@H]3C4=C(CC[C@H]3[C@@H]1CCC2=O)CC(OC)=CC4 -US20050256176A1,2,CCC1(CS(=O)(=O)Cl)NC(=O)NC1=O.Cc1cc(COc2ccc(N)cc2)c2ccccc2n1>>CCC1(CS(=O)(=O)Nc2ccc(OCc3cc(C)nc4ccccc34)cc2)NC(=O)NC1=O -US06884868B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC1(c2ccc(Cl)cc2)CCNCC1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 -US20150018363A1,6,Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccccc4)cc3=O)cc21>>Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21 -US07456218B2,7,Cc1cc(OC2CCCCO2)ccc1-c1cccc(C=O)c1>>Cc1cc(OC2CCCCO2)ccc1-c1cccc(CO)c1 -US20110003820A1,7,CC1=NCCn2c(C)ccc21>>Cc1ccc2n1CCNC2C -US20080009479A1,1,CC(C)(C)OC(=O)N1CCc2ccc(Oc3ccc(Cl)nc3)cc2CC1.O=C1CCCN1>>CC(C)(C)OC(=O)N1CCc2ccc(Oc3ccc(N4CCCC4=O)nc3)cc2CC1 -US04388469,1,C1COCCN1.ClCCCOC(CCCc1ccccc1)c1ccccc1>>c1ccc(CCCC(OCCCN2CCOCC2)c2ccccc2)cc1 -US06967196B1,9,C[C@H](CCBr)N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1.[N-]=[N+]=[N-]>>C[C@H](CCN=[N+]=[N-])N(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1 -US07271180B2,1,OCCCl.Oc1cccc2[nH]ccc12>>ClCCOc1cccc2[nH]ccc12 -US07786113B2,2,CC(=O)Cl.CC(C)OC(=O)Nc1cnc2[nH]c(-c3cccc(N)c3)nc2c1>>CC(=O)Nc1cccc(-c2nc3cc(NC(=O)OC(C)C)cnc3[nH]2)c1 -US08354444B2,8,CC(C)(CO)C1=CCN(Cc2ccccc2)CC1>>CC(C)(C=O)C1=CCN(Cc2ccccc2)CC1 -US06635657B1,1,C1CCNC1.O=C1CCN(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)CC1>>O=C(Nc1ccc(Cl)cn1)c1ccccc1NC(=O)N1CCC(N2CCCC2)CC1 -US20030045719A1,7,COC(=O)c1c(Cl)nc2cc3c(cc2c1CN1CCN(C)CC1)OCCO3>>CN1CCN(Cc2c(CO)c(Cl)nc3cc4c(cc23)OCCO4)CC1 -US20140094462A1,1,CC(C)(C)OC(=O)C[C@@H]1CC=CCCC(=O)N[C@H](c2ccccc2)COC1=O.CI>>CN1C(=O)CCC=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)OC[C@H]1c1ccccc1 -US08183262B2,3,FC(F)c1cc(-c2ccc(C(F)(F)F)cc2)nc(Cl)n1.OB(O)c1cccc(Br)c1>>FC(F)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2cccc(Br)c2)n1 -US20080293771A1,6,CN(C(=O)c1ccc(-n2cccn2)cc1)[C@@H]1CCN(C(=O)OC(C)(C)C)C1>>CN(C(=O)c1ccc(-n2cccn2)cc1)[C@@H]1CCNC1 -US20070191447A1,7,O=[N+]([O-])c1cc(Br)ccc1O>>Nc1cc(Br)ccc1O -US09108983B2,6,O=C(OCc1ccccc1)N1Cc2ccccc2C[C@H]1CN1CCOCC1>>c1ccc2c(c1)CN[C@H](CN1CCOCC1)C2 -US20070244125A1,2,CCOC(=O)c1cc2cc(C(=O)O)ccc2[nH]1.CN(C)C1CCCNC1>>CCOC(=O)c1cc2cc(C(=O)N3CCCC(N(C)C)C3)ccc2[nH]1 -US20130274266A1,1,C[Si](C)(C)CCOCCl.FC(F)(F)c1c[nH]cn1>>C[Si](C)(C)CCOCn1cnc(C(F)(F)F)c1 -US07517996B2,6,COC(=O)c1conc1-c1ccc(CCl)cc1>>O=C(O)c1conc1-c1ccc(CCl)cc1 -US20100075961A1,1,BrC1CCCCCC1.COC(=O)C(C)(C)C(c1ccccc1)c1ccc2[nH]ncc2c1>>COC(=O)C(C)(C)C(c1ccccc1)c1ccc2c(cnn2C2CCCCCC2)c1 -US20140275030A1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Nc1c(OCC(=O)c2ccccn2)cccc1[N+](=O)[O-]>>C=C(COc1cccc([N+](=O)[O-])c1N)c1ccccn1 -US04509972,2,COc1nc(N)nc2nccnc12.O=C=NS(=O)(=O)Oc1ccccc1F>>COc1nc(NC(=O)NS(=O)(=O)Oc2ccccc2F)nc2nccnc12 -US04231944,6,COC(=O)/C=C(C)/C=C/C(F)=C(C)/C=C/c1c(C)sc(C)c1C>>CC(=C\C(=O)O)/C=C/C(F)=C(C)/C=C/c1c(C)sc(C)c1C -US20070244154A1,1,CNC(=O)c1cc2c(nc(C)n2C)c2c1[C@@H](O)[C@H](O)[C@@H](c1ccccc1)N2.COCCO>>CNC(=O)c1cc2c(nc(C)n2C)c2c1[C@H](OCCOC)[C@H](O)[C@@H](c1ccccc1)N2 -US04266963,1,CC(C)(CCl)C(=O)CBr.Cc1nn(C)c(O)c1C(=O)c1ccc(Cl)cc1Cl>>Cc1nn(C)c(OCC(=O)C(C)(C)CCl)c1C(=O)c1ccc(Cl)cc1Cl -US20100144747A1,7,CCC(=O)c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)(F)F>>CCC(O)c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)(F)F -US08623866B2,6,CCOC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C>>Cn1ncc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)O -US20150158882A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CCO)CC1 -US20090253671A1,2,CC(C)(C)OC(=O)N1CC(N)C1.Cc1[nH]c(C(=O)O)c(Cl)c1Cl>>Cc1[nH]c(C(=O)NC2CN(C(=O)OC(C)(C)C)C2)c(Cl)c1Cl -US06380230B1,3,COc1cccc(OC)c1.O=C(Cl)CCCC1CCCCC1>>COc1ccc(C(=O)CCCC2CCCCC2)c(OC)c1 -US03985907,1,CCCC(=O)C(Cl)CC.Cc1cc(S)c(C)o1>>CCCC(=O)C(CC)Sc1cc(C)oc1C -US20030203889A1,1,O=C(CBr)c1ccc(F)cc1.O=S(=O)(c1ccc(Br)cc1)C1CCNCC1>>O=C(CN1CCC(S(=O)(=O)c2ccc(Br)cc2)CC1)c1ccc(F)cc1 -US05958918,1,COc1ccc2ccc(S(=O)(=O)N[C@H]3CCN(Cc4cccc(C#N)c4)C3=O)cc2c1.ClCc1ccncc1>>COc1ccc2ccc(S(=O)(=O)N(Cc3ccncc3)[C@H]3CCN(Cc4cccc(C#N)c4)C3=O)cc2c1 -US20110263557A1,1,CS(=O)(=O)N1CCNCC1.O=Cc1ccc(O)cc1>>CS(=O)(=O)N1CCN(Cc2ccc(O)cc2)CC1 -US20080095711A1,6,CCCCCCOCCCCCCCCC#CCCCC(=O)OC>>CCCCCCOCCCCCCCCC#CCCCC(=O)O -US06664271B1,2,CCCCCCCCN.O=C(Cl)C1CCCN(C(=O)c2ccccc2)C1>>CCCCCCCCNC(=O)C1CCCN(C(=O)c2ccccc2)C1 -US20130158075A1,6,CCOC(=O)C1CCC(CC(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)CC1CCC(C(=O)O)CC1 -US20120245136A1,6,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1cccnc1O2>>O=C1CC2(CCNCC2)Oc2ncccc21 -US20080132542A1,4,N#Cc1nc(N2CCC(Oc3cc(F)ccc3Br)CC2)no1.[N-]=[N+]=[N-]>>Fc1ccc(Br)c(OC2CCN(c3noc(-c4nnn[nH]4)n3)CC2)c1 -US05153227,7,O=C(O)c1ccc(S(=O)(=O)C[N+](=O)[O-])cc1>>O=[N+]([O-])CS(=O)(=O)c1ccc(CO)cc1 -US07173129B2,2,CCOC(=O)Cl.COc1cc(OC)c(-c2cc3ccccc3[nH]2)cc1/C=C/C(=O)c1ccc(S(N)(=O)=O)cc1>>CCOC(=O)NS(=O)(=O)c1ccc(C(=O)/C=C/c2cc(-c3cc4ccccc4[nH]3)c(OC)cc2OC)cc1 -US20020065309A1,1,CN(C)c1ccc([C@@H]2C[C@@H]3CNCC34C(=O)N(CCN3CCOCC3)C(=O)N24)c2ccccc12.COc1ccc(C=O)cc1[N+](=O)[O-]>>COc1ccc(CN2C[C@H]3C[C@@H](c4ccc(N(C)C)c5ccccc45)N4C(=O)N(CCN5CCOCC5)C(=O)C34C2)cc1[N+](=O)[O-] -US04211783,1,O=C(O)c1ccc(NCCCCCCCCCCCC#Cc2ccc(Cl)cc2)cc1.OCC(O)CI>>O=C(OCC(O)CO)c1ccc(NCCCCCCCCCCCC#Cc2ccc(Cl)cc2)cc1 -US20080228008A1,1,C=COCC.CC1CC(=O)C2CCCCCCCCCC2(O)C1>>CCOC(C)OC12CCCCCCCCCC1C(=O)CC(C)C2 -US08269002B2,1,CC1(C)OCC(CO)O1.CCI>>CCOC[C@@H]1COC(C)(C)O1 -US20110288084A1,1,N[C@@H]1CC[C@@H](C(Cn2c(=O)cnc3ccc(F)cc32)NS(=O)(=O)c2ccccc2[N+](=O)[O-])CC1.O=Cc1ncc2c(n1)NC(=O)CO2>>O=C1COc2cnc(CN[C@@H]3CC[C@@H](C(Cn4c(=O)cnc5ccc(F)cc54)NS(=O)(=O)c4ccccc4[N+](=O)[O-])CC3)nc2N1 -US20080200448A1,6,CCOC(=O)c1cc(Cl)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1CN1CCCC1=O>>O=C(O)c1cc(Cl)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1CN1CCCC1=O -US20130059853A1,1,COCOc1c(Br)ccc(OC)c1O.FC(F)Cl>>COCOc1c(Br)ccc(OC)c1OC(F)F -US20150266916A1,2,CC(C)OC(=O)Cl.CCOc1ccc(Cc2cc([C@]34OC[C@](C(C)O)(O3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]4OCc3ccccc3)ccc2Cl)cc1>>CCOc1ccc(Cc2cc([C@]34OC[C@](C(C)OC(=O)OC(C)C)(O3)C(OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]4OCc3ccccc3)ccc2Cl)cc1 -US20040087568A1,2,CC1(C)CC(=O)Nc2cc(N)ccc21.O=C(O)c1ccccc1NCc1c[nH]c2ncccc12>>CC1(C)CC(=O)Nc2cc(NC(=O)c3ccccc3NCc3c[nH]c4ncccc34)ccc21 -US20110053931A1,2,COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCOCC1.O=C(O)c1cccn(Cc2ccccc2)c1=O>>COc1cc2c(Oc3ccc(NC(=O)c4cccn(Cc5ccccc5)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 -US20130116234A1,3,COC(=O)c1c(C(C)C)nc2c(Cl)cc(Cl)cc2c1OS(=O)(=O)C(F)(F)F.OB(O)c1ccc(F)c(Cl)c1>>COC(=O)c1c(C(C)C)nc2c(Cl)cc(Cl)cc2c1-c1ccc(F)c(Cl)c1 -US08067457B2,9,COc1ccc(N2CCC(N3CC[C@@H](NC(=O)CNC(=O)c4ccc(Cl)c(Cl)c4)C3)CC2)cc1>>COc1ccc(N2CCC(N3CC[C@@H](NC(=O)CNC(=O)c4cccc(Cl)c4)C3)CC2)cc1 -US05397798,2,CC(C)(C)c1cccc(C(=O)Cl)c1.Nc1ccccc1S(=O)(=O)NCCc1ncc[nH]1>>CC(C)(C)c1cccc(C(=O)Nc2ccccc2S(=O)(=O)NCCc2ncc[nH]2)c1 -US20110021479A1,2,CC(C)(C)OC(=O)N1CCC[C@H](N)C1.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>CC(C)(C)OC(=O)N1CCC[C@H](NC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C1 -US09040531B2,6,CN1[C@@H](Cc2ccc(OCc3ccccc3)cc2)C(=O)N(Cc2cccc3ccccc23)CC2N(C(=O)NCc3ccccc3)CCC(=O)N21>>CN1[C@@H](Cc2ccc(O)cc2)C(=O)N(Cc2cccc3ccccc23)CC2N(C(=O)NCc3ccccc3)CCC(=O)N21 -US05078748,1,O=[N+]([O-])c1cc([N+](=O)[O-])c(Cl)c(C(F)(F)F)c1.OCCO>>O=[N+]([O-])c1cc([N+](=O)[O-])c(OCCO)c(C(F)(F)F)c1 -US20060199829A1,4,NNc1ccc(Br)cc1.O=C1CCNCC1>>Brc1ccc2[nH]c3c(c2c1)CNCC3 -US20020055526A1,1,CCBr.O=c1[nH]c2ccc3ccccc3c2[nH]1>>CCn1c(=O)[nH]c2c3ccccc3ccc21 -US20100249163A1,6,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(OC)c2ccn(C)c(=O)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)C2CNCCC2(OC)c2ccn(C)c(=O)c2)C2CC2)cc(OCCOC)c1 -US07652022B2,2,CCc1ccc(N=C=O)cc1.COc1cc(Oc2ccc(N)cc2)ccn1>>CCc1ccc(NC(=O)Nc2ccc(Oc3ccnc(OC)c3)cc2)cc1 -US20130210801A1,7,Cc1ccc2c(-c3ccc(Cl)cc3)c([C@@H](COC(=O)C(C)(C)C)OC(C)(C)C)c(Cl)cc2n1>>Cc1ccc2c(-c3ccc(Cl)cc3)c([C@@H](CO)OC(C)(C)C)c(Cl)cc2n1 -US07202263B2,1,NCCOc1ccc(-n2ccnc2)cc1.O=Cc1ccc2c(c1)OCO2>>c1cn(-c2ccc(OCCNCc3ccc4c(c3)OCO4)cc2)cn1 -US07557213B2,1,BrCc1cccc(Br)n1.Cc1ccc2[nH]cc(C(=O)c3ccc(C)c(C)c3)c(=O)c2n1>>Cc1ccc2c(n1)c(=O)c(C(=O)c1ccc(C)c(C)c1)cn2Cc1cccc(Br)n1 -US07691850B2,6,CC(C)(C)OC(=O)NC(C)(C)[C@H]1CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)NC(C)(C)[C@H]1CCNC1 -US05521179,2,CC(C)C(NC(=O)Cn1cccc(N)c1=O)C(=O)C(F)(F)F.O=C(Cl)CCc1ccccc1>>CC(C)C(NC(=O)Cn1cccc(NC(=O)CCc2ccccc2)c1=O)C(=O)C(F)(F)F -US06930185B2,1,CC(=O)Nc1ccc2nc(CO)ccc2c1.CNC>>CC(=O)Nc1ccc2nc(CN(C)C)ccc2c1 -US20040122244A1,2,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.Nc1ccc(Cl)cc1>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccc(Cl)cc3)c2)=C(C)C1=O -US20120040966A1,2,CS(=O)(=O)Cl.O=C1CCNc2ccccc21>>CS(=O)(=O)N1CCC(=O)c2ccccc21 -US20110166132A1,1,CC(C)=O.COC(=O)C(CC1CC1)c1ccc(N)cn1>>COC(=O)C(CC1CC1)c1ccc(NC(C)C)cn1 -US06552225B1,2,C[C@@](O)(C(=O)Nc1ccc(S(=O)(=O)Cl)c(Cl)c1Cl)C(F)(F)F.Cc1ccc(N)nc1>>Cc1ccc(NS(=O)(=O)c2ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c2Cl)nc1 -US20100179109A1,6,CCc1cc(CN(C)C(=O)OC(C)(C)C)ccc1C(=O)OC>>CCc1cc(CN(C)C(=O)OC(C)(C)C)ccc1C(=O)O -US20130123502A1,2,CCOC(=O)Cl.c1ccc([C@@H]2NCCc3ccccc32)cc1>>CCOC(=O)N1CCc2ccccc2[C@@H]1c1ccccc1 -US20110098296A1,1,CCN(CC)CCOc1cccc(N)c1.O=C(Cc1cccs1)Nc1cccc(-c2ncsc2-c2ccnc(Cl)n2)c1>>CCN(CC)CCOc1cccc(Nc2nccc(-c3scnc3-c3cccc(NC(=O)Cc4cccs4)c3)n2)c1 -US06358948B1,3,CC1(C)OC(C(F)(F)F)Nc2ccc(Br)cc21.Cc1cc(C#N)sc1Br>>Cc1cc(C#N)sc1-c1ccc2c(c1)C(C)(C)OC(C(F)(F)F)N2 -US20050282858A1,1,CI.O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-n5c(=O)[nH]c6ccccc65)cc4)CC3)C2)c2ccncc21>>Cn1c(=O)n(-c2ccc(C3(C(=O)N4CC[C@@]5(C4)OC(=O)c4cnccc45)CC3)cc2)c2ccccc21 -US04189484,2,COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC.O=C(Cl)C=Cc1ccccc1>>COc1cc2nc(N3CCN(C(=O)C=Cc4ccccc4)CC3)nc(N)c2cc1OC -US20070021434A1,2,O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21.c1ccc(CNC2CCCCC2)cc1>>O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(Cc1ccccc1)C1CCCCC1)OCC1c2ccccc2-c2ccccc21 -US20110009454A1,2,COc1cccc(CN)c1F.Cc1ccc(C(=O)O)c(N)n1>>COc1cccc(CNC(=O)c2ccc(C)nc2N)c1F -US20080318923A1,1,CN(C)C(=O)CC[C@H](N)C(=O)N(C)C.COc1ccccc1C1(Cl)C(=O)Nc2ccc(Cl)cc21>>COc1ccccc1C1(N[C@@H](CCC(=O)N(C)C)C(=O)N(C)C)C(=O)Nc2ccc(Cl)cc21 -US04228168,2,COC(=O)CCCC(=O)Cl.c1ccc2c(CCNCC3CC3)c[nH]c2c1>>COC(=O)CCCC(=O)N(CCc1c[nH]c2ccccc12)CC1CC1 -US09156840B2,2,CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(Cc1cccc(C(=O)O)c1)CN2c1ccccc1.OCCN1CCOCC1>>CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(Cc1cccc(C(=O)OCCN3CCOCC3)c1)CN2c1ccccc1 -US08242145B2,3,CCOC(=O)Cc1cccc(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1.Cc1noc(C)c1Br>>CCOC(=O)Cc1cccc(Oc2ccc(-c3c(C)noc3C)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1 -US20110112158A1,1,CCOC(=O)CBr.COCCCNc1noc2ccc(COc3ccc(-c4cc(F)c(F)cc4OC)cc3)cc12>>CCOC(=O)CN(CCCOC)c1noc2ccc(COc3ccc(-c4cc(F)c(F)cc4OC)cc3)cc12 -US20060229336A1,6,Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2cccc(F)c2)CCN(C(=O)C(C)(NC(=O)OC(C)(C)C)C(C)C)CC1>>Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2cccc(F)c2)CCN(C(=O)C(C)(N)C(C)C)CC1 -US20120110702A1,6,CC(C)(C)OC(=O)Nc1cn(-c2cccnc2)nc1Cl>>Nc1cn(-c2cccnc2)nc1Cl -US06774138B2,3,C#C[Si](C)(C)C.O=S(=O)(Oc1cncc(Cl)c1)C(F)(F)F>>C[Si](C)(C)C#Cc1cncc(Cl)c1 -US04920223,2,COC(=O)c1ccccc1S(=O)(=O)N=C=O.Cn1cc(Cl)nc(N)c1=O>>COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(Cl)cn(C)c1=O -US20090312328A1,2,CCO.Cc1cc(C(=O)O)ccc1F>>CCOC(=O)c1ccc(F)c(C)c1 -US20130143892A1,2,Cc1cnc(N2CCC(NC3CC3)CC2)cn1.O=C(O)c1ccc(-c2cnco2)nc1>>Cc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)nc3)C3CC3)CC2)cn1 -US20040224952A1,3,CC1CCCN1CCc1cc2cc(Br)ccc2n1C.N#Cc1ccc(B(O)O)cc1>>CC1CCCN1CCc1cc2cc(-c3ccc(C#N)cc3)ccc2n1C -US07759387B2,2,CC(C)(C)OC(=O)NCC(=O)c1ccc(OCC(=O)O)cc1.CC(C)O>>CC(C)OC(=O)COc1ccc(C(=O)CNC(=O)OC(C)(C)C)cc1 -US20030166628A1,3,CCC(Br)C(=O)Cl.Clc1ccc2sccc2c1>>CCC(Br)C(=O)c1cc2cc(Cl)ccc2s1 -US20100137610A1,1,CC(=O)N1CCNCC1.Cc1ccc(N(C)S(=O)(=O)c2cccs2)c2[nH]c(-c3ncc(CCl)s3)cc12>>CC(=O)N1CCN(Cc2cnc(-c3cc4c(C)ccc(N(C)S(=O)(=O)c5cccs5)c4[nH]3)s2)CC1 -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.Cc1cc(=O)oc2cc(O)ccc12>>Cc1cc(=O)oc2cc(Oc3ncnc4c3cnn4C3CCN(C(=O)OC(C)(C)C)CC3)ccc12 -US04182769,2,CCOC(=O)Cl.Fc1ccc(-c2nc(SC(F)(F)C(F)F)[nH]c2-c2ccc(F)cc2)cc1>>CCOC(=O)n1c(SC(F)(F)C(F)F)nc(-c2ccc(F)cc2)c1-c1ccc(F)cc1 -US20150238558A1,1,COC(=O)c1ccc(CBr)cc1.COc1cccc([C@@H](C)N)c1>>COC(=O)c1ccc(CN[C@H](C)c2cccc(OC)c2)cc1 -US09040538B2,7,Cc1noc(C)c1C=O>>Cc1noc(C)c1CO -US20140275129A1,2,COc1ccc2c(c1OC)CCNC2.O=C(O)c1nc(-c2ccc(F)cc2)nc2ccccc12>>COc1ccc2c(c1OC)CCN(C(=O)c1nc(-c3ccc(F)cc3)nc3ccccc13)C2 -US07122546B2,1,CCN(CC)c1cc(Cl)nnc1CCl.Fc1cccc(-c2ncc[nH]2)n1>>CCN(CC)c1cc(Cl)nnc1Cn1ccnc1-c1cccc(F)n1 -US20130150339A1,3,COc1cc(C#N)ccc1B(O)O.O=S(=O)(Oc1c(F)c(F)c(F)c(F)c1F)c1ccc2c(Cl)nccc2c1>>COc1cc(C#N)ccc1-c1nccc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12 -US20110294850A1,2,O=C=Nc1ccc(Oc2ccccc2)cc1.Oc1ccc2c(c1)CCN2Cc1ccccc1>>O=C(Nc1ccc(Oc2ccccc2)cc1)Oc1ccc2c(c1)CCN2Cc1ccccc1 -US20030105092A1,3,CCOC(=O)CCCCCCN(Cc1ccc(C=O)cc1)S(C)(=O)=O.[Mg+]CCc1ccccc1>>CCOC(=O)CCCCCCN(Cc1ccc(C(O)CCc2ccccc2)cc1)S(C)(=O)=O -US20090099160A1,1,CN1CCC(NC(=O)c2ccc(I)cc2)CC1.Cc1ncc(-c2nc(N)ncc2F)n1C(C)C>>Cc1ncc(-c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3)ncc2F)n1C(C)C -US07279470B2,3,C=Cc1ccccc1.CN(C(=O)Oc1ccc(I)cc1)c1ccccc1>>CN(C(=O)Oc1ccc(C=Cc2ccccc2)cc1)c1ccccc1 -US05968875,1,C[S-].FC(F)(F)c1cc(Br)cnc1Cl>>CSc1ncc(Br)cc1C(F)(F)F -US05539112,1,CC(=O)Nc1ccc(-c2cc(=O)c3c(N)c(F)cc(F)c3o2)cc1F.CCOC(=O)CBr>>CCOC(=O)CN(C(C)=O)c1ccc(-c2cc(=O)c3c(N)c(F)cc(F)c3o2)cc1F -US20040138223A1,2,CC(C)c1ccc(NCc2ccc(N(C)C)cc2)cc1.Cc1ccc(OCc2ccccc2)c2c1C(C(=O)O)CCC2>>Cc1ccc(OCc2ccccc2)c2c1C(C(=O)N(Cc1ccc(N(C)C)cc1)c1ccc(C(C)C)cc1)CCC2 -US08933085B2,10,COC(=O)c1cc(C)cc(F)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(F)cc(CBr)c1 -US20110257137A1,7,CN1CCN(c2nc3ccc(Cl)cc3c(N)c2[N+](=O)[O-])CC1>>CN1CCN(c2nc3ccc(Cl)cc3c(N)c2N)CC1 -US20050090502A1,6,COc1ccc(CN2C(=O)CN(c3ccc(C[C@H](NC(=O)[C@H](Cc4ccccc4)NC(C)=O)C(=O)OCc4ccccc4)cc3)S2(=O)=O)cc1>>COc1ccc(CN2C(=O)CN(c3ccc(C[C@H](NC(=O)[C@H](Cc4ccccc4)NC(C)=O)C(=O)O)cc3)S2(=O)=O)cc1 -US20100286120A1,7,O=C1c2ccc(Oc3cccc(Cl)c3)nc2OCCN1Cc1ccccc1>>Clc1cccc(Oc2ccc3c(n2)OCCN(Cc2ccccc2)C3)c1 -US20040147565A1,6,CCOC(=O)COc1cc(F)cc(C2(OC)CCOCC2)c1>>COC1(c2cc(F)cc(OCC(=O)O)c2)CCOCC1 -US20140296252A1,1,CCOC(=N)CC(C)C.CCOC(=O)Cl>>CCOC(=O)N=C(CC(C)C)OCC -US20050014812A1,7,C=Cc1cc(OCC)ccc1Cn1c(C)nc2c(C)cc(OCCCC(=O)OCC)cc21>>CCOC(=O)CCCOc1cc(C)c2nc(C)n(Cc3ccc(OCC)cc3CC)c2c1 -US20060229312A1,2,CCCS(=O)(=O)Cl.Cc1ccc2c(N3CCN(CCc4cccc(N)c4)CC3)cccc2n1>>CCCS(=O)(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 -US04781750,1,CCOC(=O)C(C(=O)N(C)C)=C(O)c1ccc(Cl)cc1Cl.ICc1ccccc1>>CCOC(=O)C(C(=O)N(C)C)=C(OCc1ccccc1)c1ccc(Cl)cc1Cl -US20030095958A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(C(=O)Nc2ccc3ccccc3c2)C1>>CC(C)(C)OC(=O)N1CCNC(C(=O)Nc2ccc3ccccc3c2)C1 -US20040214721A1,2,CCS(=O)(=O)N[C@H](C(=O)O)C(C)C.COc1cc([C@@H]2CCCC[C@H]2N)ccc1O>>CCS(=O)(=O)N[C@H](C(=O)N[C@@H]1CCCC[C@H]1c1ccc(O)c(OC)c1)C(C)C -US06420385B1,1,Cn1c(Cl)nc(-c2ccncc2)c(-c2cccc(C(F)(F)F)c2)c1=O.NCC[C@H](N)c1ccccc1>>Cn1c(NCC[C@H](N)c2ccccc2)nc(-c2ccncc2)c(-c2cccc(C(F)(F)F)c2)c1=O -US20070072813A1,1,CC(C)I.Cc1c(Cc2ccc(O)cc2F)c(O[C@@]2(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1C(C)C>>Cc1c(Cc2ccc(OC(C)C)cc2F)c(O[C@@]2(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1C(C)C -US04277498,6,CCCCCC(C)(C)NC(=O)CNCc1ccccc1>>CCCCCC(C)(C)NC(=O)CN -US20100324284A1,6,CCN1CCN(c2cc(N3CCc4c(-c5cnc(N(Cc6ccc(OC)cc6)Cc6ccc(OC)cc6)nc5)nc(N5CCOCC5)nc43)ccn2)CC1>>CCN1CCN(c2cc(N3CCc4c(-c5cnc(NCc6ccc(OC)cc6)nc5)nc(N5CCOCC5)nc43)ccn2)CC1 -US20040121965A1,6,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](NC)C(C)(C)c1ccsc1)C(C)(C)C>>CN[C@@H](C(=O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)O)C(C)C)C(C)(C)C)C(C)(C)c1ccsc1 -US06887889B2,6,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(I)cc2)CC1>>N#CC1(c2ccc(I)cc2)CCNCC1 -US07572808B2,1,FC(F)(F)c1ccc(CCl)cn1.O=c1[nH]nc2c(Br)c(-c3ccc(Cl)cc3)ccn12>>O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(Br)c(-c3ccc(Cl)cc3)ccn12 -US20080319188A1,2,Nc1ccccc1F.O=C(O)C1(C(=O)O)CC1>>O=C(O)C1(C(=O)Nc2ccccc2F)CC1 -US20130040930A1,1,COC(=O)c1ccc(CBr)cc1.C[C@@H]1COC(=O)N1>>COC(=O)c1ccc(CN2C(=O)OC[C@H]2C)cc1 -US20120214858A1,2,CCCCCCCC/C=C\CCCCCCCC(=O)Cl.N#CC1(N)CC1>>CCCCCCCC/C=C\CCCCCCCC(=O)NC1(C#N)CC1 -US07176212B2,1,CN(C)CC(O)COc1ccc(N)cc1.Cc1ccc(C)c(Nc2ccnc(Cl)n2)c1>>Cc1ccc(C)c(Nc2ccnc(Nc3ccc(OCC(O)CN(C)C)cc3)n2)c1 -US08034812B2,2,Cc1cc(C(=O)Cl)n(C)n1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)n(C)n1 -US20110112135A1,1,CCc1nc2c(C#N)cccn2c1-c1cccc(O)c1.COc1ccc(CN(Cc2ccc(OC)cc2)S(=O)(=O)c2cccc(Br)c2)cc1>>CCc1nc2c(C#N)cccn2c1-c1cccc(Oc2cccc(S(=O)(=O)N(Cc3ccc(OC)cc3)Cc3ccc(OC)cc3)c2)c1 -US20090149483A1,8,CC(O)c1c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)n(Cc2ccccc2Cl)c2c(=O)n(C)c(=O)n(C)c12>>CC(=O)c1c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)n(Cc2ccccc2Cl)c2c(=O)n(C)c(=O)n(C)c12 -US08173650B2,1,CC(C)(O)C1CCNCC1.Cn1c(C=O)nc2c(N3C4CCC3COC4)nc(Cl)nc21>>Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3C4CCC3COC4)nc(Cl)nc21 -US20060211678A1,2,Clc1ncnc2[nH]ccc12.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)n1ccc2c(Cl)ncnc21 -US20150073124A1,5,CCOC(=O)C(F)(F)F.NCCCCO>>O=C(NCCCCO)C(F)(F)F -US20120202785A1,6,COC(=O)c1c(F)ccc2nc([C@H](C)Nc3ncnc4c3ncn4C3CCCCO3)n(-c3ccccc3)c12>>C[C@H](Nc1ncnc2c1ncn2C1CCCCO1)c1nc2ccc(F)c(C(=O)O)c2n1-c1ccccc1 -US20070270421A1,2,CCOC(=O)CN1CCNCC1.O=C(Cl)c1ccccc1>>CCOC(=O)CN1CCN(C(=O)c2ccccc2)CC1 -US08586751B2,1,C1CCNCC1.CS(=O)(=O)c1ccc(Nc2nc(Cl)ccc2C(N)=O)cc1>>CS(=O)(=O)c1ccc(Nc2nc(N3CCCCC3)ccc2C(N)=O)cc1 -US08309546B2,1,BrCC1CC1.Clc1nc(N2CCOCC2)c2nc[nH]c2n1>>Clc1nc(N2CCOCC2)c2ncn(CC3CC3)c2n1 -US07691882B2,6,Cc1nc(N)ccc1C#C[Si](C)(C)C>>C#Cc1ccc(N)nc1C -US06586424B2,1,CC(=O)N1CCNCC1.CC(=O)c1ccnc(NC(=O)OC(C)(C)C)c1>>CC(=O)N1CCN(C(C)c2ccnc(NC(=O)OC(C)(C)C)c2)CC1 -US05354753,2,COC(=O)[C@@H](N)CCCNC(=O)c1ccccc1.O=C(O)c1ccc2c(c1)CCN2C(=O)OCc1ccccc1>>COC(=O)[C@H](CCCNC(=O)c1ccccc1)NC(=O)c1ccc2c(c1)CCN2C(=O)OCc1ccccc1 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.COc1ncc(B(O)O)cc1Cl>>CCCNC(=O)c1nnc2c(-c3cnc(OC)c(Cl)c3)cccc2c1N -US08008322B2,2,CC1(C)OB(c2ccc(N=C=O)cc2)OC1(C)C.CCOc1ccc(C(F)(F)F)cc1N>>CCOc1ccc(C(F)(F)F)cc1NC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1 -US06051712,6,COc1ccccc1SCCCOC1CCCCO1>>COc1ccccc1SCCCO -US20100298324A1,6,COC(=O)c1ccc2c(=O)n(-c3ncc(OC)cc3OC)c(=S)[nH]c2c1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)c(OC)c1 -US20150191465A1,1,C[C@H](NC(=O)OC(C)(C)C)c1nc2ccn(C)c2cc1N1CCCC(O)C1.O=C1NC(=O)c2ccccc21>>C[C@H](NC(=O)OC(C)(C)C)c1nc2ccn(C)c2cc1N1CCCC(N2C(=O)c3ccccc3C2=O)C1 -US05013741,1,Cc1ccccc1C=O.Nc1c2c(nc3ccccc13)CCCC2>>Cc1ccccc1C=Nc1c2c(nc3ccccc13)CCCC2 -US06300342B1,2,N#Cc1ccc(CCC(=O)N2CCCc3cc(S(=O)(=O)Cl)ccc32)cc1.Nc1ccccc1>>N#Cc1ccc(CCC(=O)N2CCCc3cc(S(=O)(=O)Nc4ccccc4)ccc32)cc1 -US20150266874A1,2,CC(C)N.C[Si](C)(C)CCOCn1cc(C(=O)O)c(-c2nc(-c3ccccc3)cs2)n1>>CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)nc1-c1nc(-c2ccccc2)cs1 -US05556864,1,CN(C)CCCCl.Oc1ccccc1CCCCc1ccccc1>>CN(C)CCCOc1ccccc1CCCCc1ccccc1 -US20140296306A1,2,O=C(O)CCCOCc1ccccc1.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(CCCOCc1ccccc1)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20020193367A1,2,CC(C)(C)OC(=O)Nc1cc(N2CCCCC2)c(C#N)cc1N.Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)on1>>Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C#N)c(N4CCCCC4)cc3NC(=O)OC(C)(C)C)c2)on1 -US20120035140A1,2,CC(C)(C)OC(=O)NCCCCCCN.O=S(=O)(Cl)c1ccc(Oc2ccccc2)cc1>>CC(C)(C)OC(=O)NCCCCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 -US05308854,1,CCc1cc(N)c(=O)[nH]c1C.Cc1ccc(C)c2oc(CCl)nc12>>CCc1cc(NCc2nc3c(C)ccc(C)c3o2)c(=O)[nH]c1C -US05814646,2,COc1ccc2nc(Sc3ccc(N)cc3)ccc2c1.FC(F)(F)c1cc(N=C=S)ccc1Cl>>COc1ccc2nc(Sc3ccc(NC(=S)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3)ccc2c1 -US20070232594A1,2,NCCN1Cc2ccccc2N(C(=O)c2ccc(N3CCCC3)cc2Cl)CC1=O.O=C(Cl)c1ccccc1>>O=C(NCCN1Cc2ccccc2N(C(=O)c2ccc(N3CCCC3)cc2Cl)CC1=O)c1ccccc1 -US08580968B2,6,COc1ccc2nc(N3CC[C@@H](N4CCCCC4)C3)sc2c1>>Oc1ccc2nc(N3CC[C@@H](N4CCCCC4)C3)sc2c1 -US20100324140A1,1,COC(=O)c1ccc(C(O)CC(C)C)cc1.Oc1ccc(Br)c(C2OCCCO2)c1>>COC(=O)c1ccc(C(CC(C)C)Oc2ccc(Br)c(C3OCCCO3)c2)cc1 -US20150238473A1,3,OB(O)c1ccccc1.OC(c1ccccc1)(c1ccccc1)C1CCN(CCc2ccc(Br)cc2)CC1>>OC(c1ccccc1)(c1ccccc1)C1CCN(CCc2ccc(-c3ccccc3)cc2)CC1 -US20060189661A1,1,C[O-].N#Cc1cc(F)cc(F)c1>>COc1cc(F)cc(C#N)c1 -US07569601B2,3,CC(=O)Nc1ccc(B(O)O)cc1.CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(Br)cc2)CC(C)(C)C1>>CC(=O)Nc1ccc(-c2ccc(C(=C3CC(C)(C)CC(C)(C)C3)c3ccc(O)cc3)cc2)cc1 -US04988704,1,C[O-].Cc1cc(Cl)nc(Nc2ccccc2)n1>>COc1cc(C)nc(Nc2ccccc2)n1 -US20110028509A1,6,CCOc1ccc(S(=O)(=O)N(Cc2ccc(C(=O)NC3C4CN(C(=O)OC(C)(C)C)CC43)cc2)Cc2ccccn2)cc1>>CCOc1ccc(S(=O)(=O)N(Cc2ccc(C(=O)NC3C4CNCC43)cc2)Cc2ccccn2)cc1 -US20130109661A1,1,CC1CCC(C)N1.Nc1cccc(F)n1>>CC1CCC(C)N1c1cccc(N)n1 -US20130190307A1,7,CC(C)(C#N)c1ccc([N+](=O)[O-])cn1>>CC(C)(C#N)c1ccc(N)cn1 -US20100068197A1,6,COc1ccc(N(C)c2nc(NCCNC(=O)OC(C)(C)C)nc3ccccc23)cc1OC>>COc1ccc(N(C)c2nc(NCCN)nc3ccccc23)cc1OC -US04762829,2,CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC(=O)O.CCN1CCCC(N)C1>>CCN1CCCC(NC(=O)C=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)C1 -US04115407,1,NC1CCOc2ccccc21.O=Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(C=NC2CCOc3ccccc32)c1 -US20110312932A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCC1CCOCC1>>Cc1ccc(S(=O)(=O)OCCC2CCOCC2)cc1 -US20100093705A1,1,CC=CCBr.Oc1ccccc1I>>CC=CCOc1ccccc1I -US20110301134A1,6,CCOC(=O)C(C)(C)CC#Cc1ccc(-c2onc(C)c2NC(=O)OC(C)c2ccccc2Cl)cc1>>Cc1noc(-c2ccc(C#CCC(C)(C)C(=O)O)cc2)c1NC(=O)OC(C)c1ccccc1Cl -US20100331293A1,1,Cc1c(-c2cccc(F)c2)nc2ccccc2c1Cl.Nc1cc(N2CCOCC2)ccc1N1CCOCC1>>Cc1c(-c2cccc(F)c2)nc2ccccc2c1Nc1cc(N2CCOCC2)ccc1N1CCOCC1 -US20110105470A1,2,O=C(Cl)c1cccc([N+](=O)[O-])c1.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccccc2C2=C1SCC1(CCN(C(=O)c3cccc([N+](=O)[O-])c3)CC1)O2 -US04990515,1,C=O.CC1CN(c2cc3nc4c(cc3cc2F)c(=O)c(C(=O)O)cn4C2CC2)CCN1>>CC1CN(c2cc3nc4c(cc3cc2F)c(=O)c(C(=O)O)cn4C2CC2)CCN1C -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)c(C)c3)c2cc1OC.Cc1cccc(C(=O)N=C=S)c1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4cccc(C)c4)c(C)c3)c2cc1OC -US07557127B2,6,O=C(/C=C/c1cnc(N[C@@H]2CCN(Cc3ccccc3F)C2)cn1)NOC1CCCCO1>>O=C(/C=C/c1cnc(N[C@@H]2CCN(Cc3ccccc3F)C2)cn1)NO -US20120165334A1,9,COc1cccc(Oc2nc3ccccc3n2-c2cc(C)nc(Cl)n2)c1.[NH4+]>>COc1cccc(Oc2nc3ccccc3n2-c2cc(C)nc(N)n2)c1 -US20150175567A1,1,CC(C)OC(=O)COc1cccc(NC2CCc3ccc(-c4cccc(F)c4)cc32)c1.CI>>CC(C)OC(=O)COc1cccc(N(C)C2CCc3ccc(-c4cccc(F)c4)cc32)c1 -US05908858,4,CCC(C=O)CC(=O)c1ccc(OC)cc1.Nc1ccc(S(N)(=O)=O)cc1>>CCc1cc(-c2ccc(OC)cc2)n(-c2ccc(S(N)(=O)=O)cc2)c1 -US04182776,2,CS(=O)(=O)Cl.OCCOc1cccc2ccccc12>>CS(=O)(=O)OCCOc1cccc2ccccc12 -US05106871,6,COC(=O)COc1c(C(=O)CCc2ccc(OC)cc2)ccc(OC)c1CCC(C)C>>COc1ccc(CCC(=O)c2ccc(OC)c(CCC(C)C)c2OCC(=O)O)cc1 -US20130237535A1,3,CC1(C)OB(c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)OC1(C)C.Cc1cnc2cc(Br)ccc2c1>>Cc1cnc2cc(-c3ccc(S(=O)(=O)N4CCC5(CC4)CN(C4CC4)C(=O)CO5)cc3)ccc2c1 -US20140336108A1,2,CN1CCN(CCCN)CC1.Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)O)sc34)cc2F)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCN(C)CC5)sc34)cc2F)c1 -US20020002190A1,2,Nc1ccccn1.O=C(O)C(CC1CCCC1)c1ccc(-c2cccc3ccccc23)cc1>>O=C(Nc1ccccn1)C(CC1CCCC1)c1ccc(-c2cccc3ccccc23)cc1 -US20120101105A1,1,CC(C)(C)OC(=O)CBr.C[C@@H](NC(=O)[C@H]1C[C@@H]1c1ccc(O)cc1)c1ccc(OCC(F)(F)F)cn1>>C[C@@H](NC(=O)[C@H]1C[C@@H]1c1ccc(OCC(=O)OC(C)(C)C)cc1)c1ccc(OCC(F)(F)F)cn1 -US20050256316A1,2,CC(=O)OC(C)=O.COc1c(Cl)cc(C)c(C)c1N>>COc1c(Cl)cc(C)c(C)c1NC(C)=O -US08648038B2,6,CCOC(=O)CC(OC)c1ccc(NC(=O)C(C)Oc2ccc(C(C)C)cc2Br)cc1>>COC(CC(=O)O)c1ccc(NC(=O)C(C)Oc2ccc(C(C)C)cc2Br)cc1 -US08329726B2,2,CCn1cncc1-c1cc2nccc(Oc3ccc(N)cc3F)c2s1.O=C(O)CC(=O)Nc1ccccc1F>>CCn1cncc1-c1cc2nccc(Oc3ccc(NC(=O)CC(=O)Nc4ccccc4F)cc3F)c2s1 -US06251928B1,3,O=C1CSC(=S)N1.O=Cc1ccc(OCc2cccc3ccccc23)cc1>>O=C1NC(=S)SC1=Cc1ccc(OCc2cccc3ccccc23)cc1 -US20110213028A1,2,CC(C)(C)OC(=O)NCCN.COc1c(C)c2c(c(O)c1C/C=C(\C)CCC(=O)O)C(=O)OC2>>COc1c(C)c2c(c(O)c1C/C=C(\C)CCC(=O)NCCNC(=O)OC(C)(C)C)C(=O)OC2 -US05620978,7,NC(=O)c1cnc(N)c([N+](=O)[O-])c1>>NC(=O)c1cnc(N)c(N)c1 -US06610711B2,1,BrCCCBr.Oc1c(Cl)cccc1Cl>>Clc1cccc(Cl)c1OCCCBr -US20150225367A1,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)c2ccc(F)cc21.CN(CCNS(C)(=O)=O)S(=O)(=O)c1ccc(Br)cn1>>CN(CCNS(C)(=O)=O)S(=O)(=O)c1ccc(-c2cn(C(=O)OC(C)(C)C)c3cc(F)ccc23)cn1 -US20090203906A1,6,COC(=O)c1ccc(CNCCc2ccccc2OC)cc1>>COC(=O)c1ccc(CNCCc2ccccc2O)cc1 -US04029787,1,CN1CCNCC1.NS(=O)(=O)c1cc(C(=O)N2CCOCC2)ccc1Cl>>CN1CCN(c2ccc(C(=O)N3CCOCC3)cc2S(N)(=O)=O)CC1 -US20100292222A1,1,CN1CCNCC1=O.CS(=O)(=O)OCCOc1ccc(N2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1>>CN1CCN(CCOc2ccc(N3CCN(c4ccc5nnc(C(F)(F)F)n5n4)CC3)cc2)CC1=O -US08557797B2,6,CCOC(=O)CC1CCC(Oc2ccc3nnc(C(C)C)n3c2)CC1>>CC(C)c1nnc2ccc(OC3CCC(CC(=O)O)CC3)cn12 -US08912179B2,6,CC(C)(C)OC(=O)N1CCc2nc(OC3CCN(C4CCC4)CC3)sc2C1>>C1CC(N2CCC(Oc3nc4c(s3)CNCC4)CC2)C1 -US20120230951A1,2,COC(=O)N[C@H](C(=O)O)C(C)C.FC1(F)CN[C@H](c2ncc(-c3ccc(Br)cc3)[nH]2)C1>>COC(=O)N[C@H](C(=O)N1CC(F)(F)C[C@H]1c1ncc(-c2ccc(Br)cc2)[nH]1)C(C)C -US20110319378A1,6,CC[C@@H](CN1CCOCC1)N1C(=O)[C@@H](CC(=O)OC(C)(C)C)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CN1CCOCC1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US20090258854A1,1,BrCCOc1ccc(Oc2nc3ncccc3s2)cc1.c1cnc(OC2CCNCC2)nc1>>c1cnc(OC2CCN(CCOc3ccc(Oc4nc5ncccc5s4)cc3)CC2)nc1 -US20120322788A1,6,CCOC(OCC)c1cccc(CCN2CCC3(CC2)CN(C(=O)c2ccc(C)s2)CCO3)c1>>Cc1ccc(C(=O)N2CCOC3(CCN(CCc4cccc(C=O)c4)CC3)C2)s1 -US20150218186A1,1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.FC(F)c1ncc(I)c2nc(Cl)ncc12>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1ncc2c(C(F)F)ncc(I)c2n1 -US20140080840A1,1,CCOC(=O)N1CCNCC1.OCCCCCBr>>CCOC(=O)N1CCN(CCCCCO)CC1 -US20150210675A1,9,CCCCCCCCCCCCc1ccc(-c2nc(C3(C(N)=O)CC3)no2)cc1>>CCCCCCCCCCCCc1ccc(-c2nc(C3(C#N)CC3)no2)cc1 -US04810713,9,OC(c1ccccc1)(c1ccccc1)c1ccncc1>>c1ccc(C(c2ccccc2)c2ccncc2)cc1 -US20020107340A1,2,CC(Br)C(=O)Br.[N-]=[N+]=NCCO>>CC(Br)C(=O)OCCN=[N+]=[N-] -US20130172360A1,2,CN1CCN(c2ccc(C(=O)O)c(N(C(=O)C(F)(F)F)C3CCOCC3)c2)CC1.Nc1n[nH]c2ncc(Sc3cc(F)cc(F)c3)cc12>>CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ncc(Sc5cc(F)cc(F)c5)cc34)c(N(C(=O)C(F)(F)F)C3CCOCC3)c2)CC1 -US20150182503A1,7,COC(=O)C(CC(F)F)(c1ccc(C(F)(F)F)cc1)n1ncc2c(NS(C)(=O)=O)cccc21>>CS(=O)(=O)Nc1cccc2c1cnn2C(CO)(CC(F)F)c1ccc(C(F)(F)F)cc1 -US20150166483A1,2,CN(C)S(=O)(=O)Cl.COc1c(N)cc(C(C)(C)C)cc1N>>COc1c(N)cc(C(C)(C)C)cc1NS(=O)(=O)N(C)C -US20060293252A1,6,COc1ccc(C(=O)c2sc(C(C)C)cc2OCc2ccccc2)cc1>>COc1ccc(C(=O)c2sc(C(C)C)cc2O)cc1 -US20150080393A1,1,COC(=O)c1ccc(C)nc1Cl.Cc1cc[nH]n1>>COC(=O)c1ccc(C)nc1-n1ccc(C)n1 -US06946467B2,1,C1CNCCN1.CC(C)(C)OC(=O)N1CCC(C=O)CC1>>CC(C)(C)OC(=O)N1CCC(CN2CCNCC2)CC1 -US20150175541A1,2,CC(C)(C)OC(=O)N1CC(C(=O)O)C1.CNOC>>CON(C)C(=O)C1CN(C(=O)OC(C)(C)C)C1 -US06333358B1,9,COc1ccccc1CN(C(=O)CCl)c1ccccc1Oc1ccccc1.[N-]=[N+]=[N-]>>COc1ccccc1CN(C(=O)CN=[N+]=[N-])c1ccccc1Oc1ccccc1 -US20120122843A1,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.COc1nc(N)ccc1Br>>COc1nc(N)ccc1-c1cnn(C(=O)OC(C)(C)C)c1 -US04078071,1,ClC(CCc1ccccc1)Cn1ccnc1.SCc1ccc(Cl)c(Cl)c1>>Clc1ccc(CSC(CCc2ccccc2)Cn2ccnc2)cc1Cl -US07514441B2,6,Cc1ccc(C(C)(C)C(=O)c2cnn3c2N(Cc2ccccc2)C(c2ccccc2)CC3(C)C)cc1>>Cc1ccc(C(C)(C)C(=O)c2cnn3c2NC(c2ccccc2)CC3(C)C)cc1 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1cc(Br)cs1>>FC(F)(F)c1cccc2c(-c3cccc(NCc4cc(Br)cs4)c3)c(Cc3ccccc3)cnc12 -US20010036946A1,2,CN1CCC(N2CCNCC2)CC1.COc1cccc(CCNC(=O)N[C@H](Cc2cc(Br)c(O)c(Br)c2)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O)c1>>COc1cccc(CCNC(=O)N[C@H](Cc2cc(Br)c(O)c(Br)c2)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)N2CCN(C3CCN(C)CC3)CC2)c1 -US20080171771A1,6,CC(C)(C)OC(=O)NC1=NC(c2ccc(O[Si](C)(C)C(C)(C)C)cc2)(c2cccc(Br)c2)c2ccccc21>>CC(C)(C)OC(=O)NC1=NC(c2ccc(O)cc2)(c2cccc(Br)c2)c2ccccc21 -US07074801B1,6,COC(=O)c1ccc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2-c2ccc3ncc(-c4nccs4)n3c2)s1>>O=C(O)c1ccc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2-c2ccc3ncc(-c4nccs4)n3c2)s1 -US07750161B2,6,O=C(NCCN1CCC(c2ccccc2)(c2ccccc2)C1)OCc1ccccc1>>NCCN1CCC(c2ccccc2)(c2ccccc2)C1 -US20060040999A1,3,COc1ccc(C(C)C)cc1B(O)O.C[C@@H]1[C@@H](c2cc(C(F)(F)F)ccc2I)OC(=O)N1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1[C@H]1OC(=O)N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C -US06703421B1,6,CC(C)(C)OC(=O)NC1Cc2ccc(C(=O)NCc3ccccc3)cc2C1>>NC1Cc2ccc(C(=O)NCc3ccccc3)cc2C1 -US20150158876A1,6,CCOC(=O)c1nn(C)c2c1CCc1cnc(OC)nc1-2>>CCOC(=O)c1nn(C)c2c1CCc1cnc(O)nc1-2 -US20100249163A1,3,CN(C)C=O.COCCOc1cc(Br)cc(Br)c1>>COCCOc1cc(Br)cc(C=O)c1 -US20030073836A1,6,CCOC(=O)c1csc(NC(=O)c2ccccc2-c2ccccc2)n1>>O=C(O)c1csc(NC(=O)c2ccccc2-c2ccccc2)n1 -US06087357,1,CS(=O)(=O)OCCCN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2c[nH]c3ccccc23)C1.c1ccc(C2CCNCC2)cc1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(CCCN2CCC(c3ccccc3)CC2)C[C@H]1Cc1c[nH]c2ccccc12 -US05475106,2,CC(C)(C)OC(=O)CNc1cccc(Cl)c1Cl.Cc1cccc(NC(=O)NCC(=O)O)c1>>Cc1cccc(NC(=O)NCC(=O)N(CC(=O)OC(C)(C)C)c2cccc(Cl)c2Cl)c1 -US20150191452A1,2,C[C@H](N)c1ccc(F)cc1.O=C(Cl)C(Br)CCBr>>C[C@H](NC(=O)C(Br)CCBr)c1ccc(F)cc1 -US20030232875A1,1,O=C1NC(=O)c2ccccc21.OCc1nocc1-c1ccccc1>>O=C1c2ccccc2C(=O)N1Cc1nocc1-c1ccccc1 -US04971993,6,O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1S(=O)(=O)c1ccccc1>>O=C(O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1S(=O)(=O)c1ccccc1 -US20130165436A1,7,O=C1COc2cnc(Br)cc2N1>>Brc1cc2c(cn1)OCCN2 -US20120209001A1,1,CC(C)(C)n1nc(CCC=O)cc1-c1ccc(F)cc1.Cc1ccc(N2CCNCC2)cc1C>>Cc1ccc(N2CCN(CCCc3cc(-c4ccc(F)cc4)n(C(C)(C)C)n3)CC2)cc1C -US04014915,2,CC(C)(C)O.CCOC(=O)C(=NOC(=O)Cl)C(C)=O>>CCOC(=O)C(=NOC(=O)OC(C)(C)C)C(C)=O -US05075440,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCSSCCN>>CC(C)(C)OC(=O)NCCSSCCN -US20120258946A1,7,O=[N+]([O-])c1ccc(C(O)(CO)CO)cc1>>Nc1ccc(C(O)(CO)CO)cc1 -US20110319393A1,6,CC(C)(C)OC(=O)N1CCC(Nc2ccc(C(F)(F)F)cn2)CC1>>FC(F)(F)c1ccc(NC2CCNCC2)nc1 -US20050085520A1,2,C[C@H](C[C@H](O)[C@@H](N)Cc1ccccc1)C(=O)NC1CC2CCC1C2.O=C(O)c1cc(OCC2CC2)cc(N2CCCC2=O)c1>>C[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(OCC2CC2)cc(N2CCCC2=O)c1)C(=O)NC1CC2CCC1C2 -US05110940,8,OCC(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=CC(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US06541505B1,1,N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(Cl)n4)cc3)cc12.NCCCCCN1CCOCC1>>N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(NCCCCCN5CCOCC5)n4)cc3)cc12 -US20100168185A1,4,CCC(N)=S.O=C(CBr)c1ccc(F)cc1>>CCc1nc(-c2ccc(F)cc2)cs1 -US08778950B2,2,CC(C)(C)N.O=C(O)c1nn(-c2cnccn2)c2c1C[C@H]1C[C@@H]21>>CC(C)(C)NC(=O)c1nn(-c2cnccn2)c2c1C[C@H]1C[C@@H]21 -US07192945B2,6,CCCCC1(CC)CN(c2ccccc2)c2cc(Br)c(OCCC(=O)N[C@@H](C(=O)OC(C)(C)C)c3ccccc3)cc2S(=O)(=O)C1>>CCCCC1(CC)CN(c2ccccc2)c2cc(Br)c(OCCC(=O)N[C@@H](C(=O)O)c3ccccc3)cc2S(=O)(=O)C1 -US20150252008A1,1,Fc1cccc(CBr)c1F.Nc1cnc(-c2ccc(C3CCC3)c(O)c2F)cn1>>Nc1cnc(-c2ccc(C3CCC3)c(OCc3cccc(F)c3F)c2F)cn1 -US20030216410A1,3,Cc1[nH]c(C=O)c(C)c1C(=O)NCCCN(C)C.O=C1Cc2ccc(-c3cccnc3)cc2N1>>Cc1[nH]c(C=C2C(=O)Nc3cc(-c4cccnc4)ccc32)c(C)c1C(=O)NCCCN(C)C -US20080090827A1,6,ClCCCOCCc1ccc(OCc2ccccc2)cc1>>Oc1ccc(CCOCCCCl)cc1 -US04814468,7,CCOC(=O)C1C(=O)C[C@@H]2CC3(C[C@H]12)OCCO3>>CCOC(=O)[C@H]1[C@H](O)C[C@@H]2CC3(C[C@@H]21)OCCO3 -US07659268B2,6,CCc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1ccc(C(=O)OC(C)(C)C)cc1>>CCc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1ccc(C(=O)O)cc1 -US20120142667A1,7,COC(=O)CCc1cccc(Nc2ncc(Cl)c(Nc3ccc(OC)cc3NS(C)(=O)=O)n2)c1C>>COc1ccc(Nc2nc(Nc3cccc(CCCO)c3C)ncc2Cl)c(NS(C)(=O)=O)c1 -US06713647B2,3,C#Cc1ccc(C2(OC(C)C)CC2)cc1.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(C#Cc2ccc(C3(OC(C)C)CC3)cc2)cc1 -US20100010053A1,6,CCOC(=O)CCc1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cc(F)cc12>>CC(C)Oc1ccc(-c2nc(-c3cc(F)cc4c(CCC(=O)O)c[nH]c34)no2)cc1C#N -US20030069271A1,8,CCCc1c(SC2CCCCC2)c2cc(Cl)ccc2[nH]c1=O.O=C(OO)c1cccc(Cl)c1>>CCCc1c(S(=O)C2CCCCC2)c2cc(Cl)ccc2[nH]c1=O -US04732903,2,CC1(C)[C@@H](C#CC(=O)OCC(Cl)(Cl)Cl)[C@H]1C(=O)O.N#C[C@@H](O)c1cccc(Oc2ccccc2)c1>>CC1(C)[C@@H](C#CC(=O)OCC(Cl)(Cl)Cl)[C@H]1C(=O)O[C@H](C#N)c1cccc(Oc2ccccc2)c1 -US08309734B2,6,COC(=O)c1cc(Cl)c(Oc2ncccc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl>>O=C(O)c1cc(Cl)c(Oc2ncccc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl -US07423030B2,3,COc1ccc(C(=O)N(C)OC)cc1.O=C(O)c1cc(Cl)ccc1Br>>COc1ccc(C(=O)c2ccc(Cl)cc2C(=O)O)cc1 -US07858613B2,2,Fc1ccc(N=C=S)c(F)c1.O=C1c2ccccc2OCCC1(CO)CO>>O=C1c2ccccc2OCCC1(CO)COC(=S)Nc1ccc(F)cc1F -US20110207747A1,6,COC(=O)c1cc(-c2cncc(C)c2)ccc1-c1cnn(C)c1>>Cc1cncc(-c2ccc(-c3cnn(C)c3)c(C(=O)O)c2)c1 -US09115134B2,1,CC(C)(C)OC(=O)Nc1nc2ccc(S)cc2s1.Clc1nnc2ccc(N3CCOCC3)nn12>>CC(C)(C)OC(=O)Nc1nc2ccc(Sc3nnc4ccc(N5CCOCC5)nn34)cc2s1 -US20150004181A1,1,CC(C)(C)OC(=O)NC1CCNC1.CN1CCC(OC(c2cccc(I)c2)c2nc3ccccc3s2)CC1>>CN1CCC(OC(c2cccc(N3CCC(NC(=O)OC(C)(C)C)C3)c2)c2nc3ccccc3s2)CC1 -US20100048636A1,7,CCNC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C>>CCNC[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C -US07332483B2,1,C1CCNC1.Cc1ccc(NC(=O)c2ccnc(Cl)c2)cc1-n1cnc2ccc(N3CCN(C)CC3)cc2c1=O>>Cc1ccc(NC(=O)c2ccnc(N3CCCC3)c2)cc1-n1cnc2ccc(N3CCN(C)CC3)cc2c1=O -US06967216B2,2,CNCCc1ccncc1.O=C(Nc1ccc2c(c1)-c1ccccc1S2=O)OCc1ccc([N+](=O)[O-])cc1>>CN(CCc1ccncc1)C(=O)Nc1ccc2c(c1)-c1ccccc1S2=O -US07211577B2,1,CC(C)Cn1nc(-c2ccc(S(C)(=O)=O)cc2)cc(COS(C)(=O)=O)c1=O.CN1CCNCC1>>CC(C)Cn1nc(-c2ccc(S(C)(=O)=O)cc2)cc(CN2CCN(C)CC2)c1=O -US20070213321A1,1,O=C(CCl)N1CCCc2ccccc21.Sc1nc2ccc(Cl)cc2s1>>O=C(CSc1nc2ccc(Cl)cc2s1)N1CCCc2ccccc21 -US20150072980A1,3,COc1cc2c(cc1N1CCN(C)CC1)CCC2=O.O=Cc1cccnc1>>COc1cc2c(cc1N1CCN(C)CC1)C/C(=C\c1cccnc1)C2=O -US20100029710A1,7,CCc1nc2c(C)cc(/C=C3\CCCC3=O)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21>>CCc1nc2c(C)cc(CC3CCCC3=O)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21 -US04810713,1,COc1cc(C(C)=O)ccc1OCCCCl.OC(c1ccccc1)(c1ccc(F)cc1)C1CCNCC1>>COc1cc(C(C)=O)ccc1OCCCN1CCC(C(O)(c2ccccc2)c2ccc(F)cc2)CC1 -US08188098B2,2,N#Cc1ccc(F)c(F)c1Oc1ncnc2c1cnn2C1CCNCC1.O=C(Cl)OC1CCCC1>>N#Cc1ccc(F)c(F)c1Oc1ncnc2c1cnn2C1CCN(C(=O)OC2CCCC2)CC1 -US09079880B2,1,COC(=O)c1cccc(O)c1.C[C@H](O)C(=O)OCc1ccccc1>>COC(=O)c1cccc(O[C@H](C)C(=O)OCc2ccccc2)c1 -US06359138B1,1,BrCC1Cc2cc(OCc3ccccc3)ccc2O1.COc1ccc(CC2(O)CCNCC2)cc1>>COc1ccc(CC2(O)CCN(CC3Cc4cc(OCc5ccccc5)ccc4O3)CC2)cc1 -US07186715B2,2,CS(=O)(=O)Cl.OC1CCCNC1>>CS(=O)(=O)N1CCCC(O)C1 -US20080085884A1,2,CC(=O)OC(C)=O.CN[C@H]1CCN(c2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn2)C1>>CC(=O)N(C)[C@H]1CCN(c2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn2)C1 -US08163901B2,2,CC(=O)N1CCc2ccc(N)cc21.CC(C)(c1ccc2c(n1)CC[C@@H](C(=O)O)C2)C(F)(F)F>>CC(=O)N1CCc2ccc(NC(=O)C3CCc4nc(C(C)(C)C(F)(F)F)ccc4C3)cc21 -US04788196,1,C1CNCCN1.NNC(=O)c1cc(Cl)ccn1>>NNC(=O)c1cc(N2CCNCC2)ccn1 -US20080039437A1,2,CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1C(F)F.NS(=O)(=O)Cc1ccc(F)cc1F>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)Cc3ccc(F)cc3F)C2)nc1C(F)F -US20100035863A1,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.Clc1cc(C2CCCCC2)nc(Cl)n1>>CC(C)(C)OC(=O)N[C@@H]1CCN(c2cc(C3CCCCC3)nc(Cl)n2)C1 -US20100112090A1,1,CCOC(=O)OC(C)Cl.COc1cc(Cl)c(-n2c(=O)[nH]c3c(C)cc(C(=O)O)nc32)cc1S(=O)(=O)C(C)(C)c1ccccc1>>CCOC(=O)OC(C)OC(=O)c1cc(C)c2[nH]c(=O)n(-c3cc(S(=O)(=O)C(C)(C)c4ccccc4)c(OC)cc3Cl)c2n1 -US08129376B2,6,COC(=O)c1ccc(N2CCCC2=O)cc1>>O=C(O)c1ccc(N2CCCC2=O)cc1 -US04746607,7,COc1cc(COC(C)=O)c(OC)c(C)c1C>>COc1cc(CO)c(OC)c(C)c1C -US07820665B2,3,CC(=O)Nc1cn2nc(Cl)ccc2n1.O=S(=O)(Nc1cc(Br)cnc1Cl)c1ccc(F)cc1>>CC(=O)Nc1cn2nc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4)c3)ccc2n1 -US20100099695A1,3,C=CCCCCCOC(=O)N[C@H](C(=O)N1C[C@H](OCC#Cc2ccccc2Br)C[C@H]1C(=O)OC)C(C)(C)C.C=C[Sn](CCCC)(CCCC)CCCC>>C=CCCCCCOC(=O)N[C@H](C(=O)N1C[C@H](OCC#Cc2ccccc2C=C)C[C@H]1C(=O)OC)C(C)(C)C -US05866589,6,CCC(C)(C)Nc1cccnc1N(C)C1CCN(C(=O)OC(C)(C)C)CC1>>CCC(C)(C)Nc1cccnc1N(C)C1CCNCC1 -US06355680B1,1,Cc1ccc(N)c(C)c1.O=C(O)Cc1ccccc1Br>>Cc1ccc(Nc2ccccc2CC(=O)O)c(C)c1 -US20100003250A1,2,C1CSCCN1.CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)O)cc4)cc3)nc21>>CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)N5CCSCC5)cc4)cc3)nc21 -US20140275524A1,3,CC(C)=O.Cc1ccc(C(C)C)c(N2C(=O)CS/C2=N\C(=O)NCCc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)c1>>Cc1ccc(C(C)C)c(N2C(=O)C(C(C)(C)O)S/C2=N\C(=O)NCCc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)c1 -US05631257,1,BrCc1ccccc1.CN1CCN(c2nc3ccccc3o2)CC1>>C[N+]1(Cc2ccccc2)CCN(c2nc3ccccc3o2)CC1 -US20150148332A1,1,C1CNC1.Cc1cnc(C)n2nc(/C=C/c3nc(Br)nn3C)nc12>>Cc1cnc(C)n2nc(/C=C/c3nc(N4CCC4)nn3C)nc12 -US20120214991A1,8,O=C(OO)c1cccc(Cl)c1.O=C1C(c2cccnc2)=C(c2ccccc2)c2ccc(OCCN3CCOCC3)cc21>>O=C1C(c2cccnc2)=C(c2ccccc2)c2ccc(OCC[N+]3([O-])CCOCC3)cc21 -US20050222247A1,1,CC(C)(C)OC(=O)N(C[C@@H](COc1ccccc1)O[Si](C)(C)C(C)(C)C)C[C@H]1CCc2cc(I)ccc2O1.COC(=O)c1ccccc1O>>COC(=O)c1ccccc1Oc1ccc2c(c1)CC[C@H](CN(C[C@@H](COc1ccccc1)O[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C)O2 -US05428038,1,COc1cc2ccc(=O)oc2cc1OCCCOS(C)(=O)=O.c1ccc(C2CCNCC2)cc1>>COc1cc2ccc(=O)oc2cc1OCCCN1CCC(c2ccccc2)CC1 -US08183262B2,3,CC(C)(C)NS(=O)(=O)c1ccc(B(O)O)cc1.Cc1cc(-c2cc(C(F)(F)F)nc(-n3cnc(I)c3)n2)ccc1C(F)(F)F>>Cc1cc(-c2cc(C(F)(F)F)nc(-n3cnc(-c4ccc(S(=O)(=O)NC(C)(C)C)cc4)c3)n2)ccc1C(F)(F)F -USRE039679E1,7,O=[N+]([O-])c1cc(Br)ccc1SCCCCl>>Nc1cc(Br)ccc1SCCCCl -US20070135467A1,4,Fc1cc(C(F)(F)F)cc(C(Cc2ccccc2)(N=C=S)c2ccc(Cl)cn2)c1.Nc1ccccc1N>>Fc1cc(C(F)(F)F)cc(C(Cc2ccccc2)(Nc2nc3ccccc3[nH]2)c2ccc(Cl)cn2)c1 -US06033601,1,ClCc1ccccc1.c1ccc2[nH]ccc2c1>>c1ccc(Cn2ccc3ccccc32)cc1 -US08153818B2,2,COC(=O)c1cc(Cl)ccc1N.O=C(Cl)OCc1ccccc1>>COC(=O)c1cc(Cl)ccc1NC(=O)OCc1ccccc1 -US06166006,6,CCOC(=O)C1=Cc2cc(-c3ccc(C)cc3)ccc2SC1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CS3)cc1 -US07220771B2,2,COC(=O)c1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1.NCc1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)c1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1 -US20040068109A1,2,COc1ccc(C(=O)Cl)cc1.Nc1c(O)cccc1[N+](=O)[O-]>>COc1ccc(C(=O)Nc2c(O)cccc2[N+](=O)[O-])cc1 -US05013737,7,NC(=O)c1cnn2c(-c3cccc(F)c3)ccnc12>>NC(=O)c1cnn2c1NCC=C2c1cccc(F)c1 -US08440822B2,1,CN(c1ncccc1CNc1nc(Nc2ccc(CCl)cc2)ncc1C(F)(F)F)S(C)(=O)=O.NC(CO)CO>>CN(c1ncccc1CNc1nc(Nc2ccc(CNC(CO)CO)cc2)ncc1C(F)(F)F)S(C)(=O)=O -US20110065707A1,2,Cn1cc(S(=O)(=O)N2CCC(F)(C(=O)O)CC2)c(C(F)(F)F)n1.Nc1ccc(OC(F)(F)F)cc1>>Cn1cc(S(=O)(=O)N2CCC(F)(C(=O)Nc3ccc(OC(F)(F)F)cc3)CC2)c(C(F)(F)F)n1 -US20050203160A1,3,CI.Cn1nc(-c2ccc(C(F)(F)F)cc2)c(Br)c1C(C)(C)O[SiH2]C(C)(C)C>>Cc1c(-c2ccc(C(F)(F)F)cc2)nn(C)c1C(C)(C)O[SiH2]C(C)(C)C -US20090270361A1,1,Cc1cc(C)[nH]n1.N#Cc1ccc(F)cc1Cl>>Cc1cc(C)n(-c2ccc(C#N)c(Cl)c2)n1 -US20100216763A1,6,CCOC(=O)c1cn2c(C(=O)NCC34CC5CC(CC(C5)C3)C4)cccc2n1>>O=C(O)c1cn2c(C(=O)NCC34CC5CC(CC(C5)C3)C4)cccc2n1 -US20110105474A1,6,CCOC(=O)/C=C/c1ccc(/C=C/C(=O)OC(C)(C)C)cc1>>CCOC(=O)/C=C/c1ccc(/C=C/C(=O)O)cc1 -US20090181950A1,7,COC(=O)/C=C\c1ccc2cccc(O)c2n1>>COC(=O)CCc1ccc2cccc(O)c2n1 -US20140364433A1,1,CI.COC(=O)c1cc(C)ccc1-c1cc[nH]n1>>COC(=O)c1cc(C)ccc1-c1ccn(C)n1 -US05182283,1,CO.OC1(c2nccnc2Cl)CN2CCC1CC2>>COc1nccnc1C1(O)CN2CCC1CC2 -US20090018123A1,2,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(n4nnc(N5CCNCC5)n4)CC3)c(F)c2)C(=O)O1.CC(=O)OC(C)=O>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(n4nnc(N5CCN(C(C)=O)CC5)n4)CC3)c(F)c2)C(=O)O1 -US20070054916A1,3,O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(B(O)O)c1.Oc1nccc2ccc(Br)cc12>>O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccc3ccnc(O)c3c2)c1 -US08865744B1,2,CC(C)(C#N)c1cc(N)on1.CC(C)(C(=O)O)S(=O)(=O)CCCC(F)(F)F>>CC(C)(C#N)c1cc(NC(=O)C(C)(C)S(=O)(=O)CCCC(F)(F)F)on1 -US05856334,2,NC1CCn2c(CCc3ccccc3)nc3cccc1c32.O=C(Cl)c1ccccn1>>O=C(NC1CCn2c(CCc3ccccc3)nc3cccc1c32)c1ccccn1 -US06110962,1,COC(=O)[C@H](O)Cc1ccccc1.Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br>>COC(=O)[C@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br -US05488160,6,COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OC(C)=O>>COc1cc(C(=O)N(C(C)C)C(C)C)ccc1O -US08772510B2,2,C1CNC1.Cn1c(Cl)nc(C(=O)O)c1C(=O)NCCc1nc2ccccc2n1C>>Cn1c(Cl)nc(C(=O)N2CCC2)c1C(=O)NCCc1nc2ccccc2n1C -US07153857B2,3,C#C[Si](C)(C)C.CS(=O)(=O)N1CCN(c2ccc(Br)cc2)CC1>>C[Si](C)(C)C#Cc1ccc(N2CCN(S(C)(=O)=O)CC2)cc1 -US20130296312A1,1,CN1CCN(c2ccc(N)cc2)CC1.CS(=O)(=O)c1ccccc1CNc1cccn2nc(Cl)nc12>>CN1CCN(c2ccc(Nc3nc4c(NCc5ccccc5S(C)(=O)=O)cccn4n3)cc2)CC1 -US20060036101A1,2,CN(C)C(=O)C(=O)c1c[nH]c2ccc(N)cc12.O=S(=O)(Cl)c1ccc2ccccc2c1>>CN(C)C(=O)C(=O)c1c[nH]c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 -US06469209B1,1,CO/N=C(/C(=O)OC)c1c(C)cccc1CBr.Cc1ccccc1O>>CO/N=C(/C(=O)OC)c1c(C)cccc1COc1ccccc1C -US20130053572A1,6,CCCCC/C=C\C/C=C\CCCCCCCCOC(CN1C(=O)c2ccccc2C1=O)OCCCCCC>>CCCCC/C=C\C/C=C\CCCCCCCCOC(CN)OCCCCCC -US20130040933A1,2,CC(C)(C)[Si](C)(C)O[C@H]1CN(c2cncc(Cl)n2)[C@@H]1C(=O)O.NCC(F)(F)F>>CC(C)(C)[Si](C)(C)O[C@H]1CN(c2cncc(Cl)n2)[C@@H]1C(=O)NCC(F)(F)F -US20120041026A1,2,CO.O=C(O)c1c(O)cccc1F>>COC(=O)c1c(O)cccc1F -US20110003820A1,2,CC(C)NC(=O)c1ccc2n1CCNC2.O=C(O)c1cc2ncc(Br)cn2n1>>CC(C)NC(=O)c1ccc2n1CCN(C(=O)c1cc3ncc(Br)cn3n1)C2 -US20090306069A1,7,O=C(O)c1ccc([N+](=O)[O-])c(F)c1>>O=[N+]([O-])c1ccc(CO)cc1F -US20080096885A1,2,Cc1c(C(=O)O)c2ccccc2[nH]c1=O.NNc1ccccc1>>Cc1c(C(=O)NNc2ccccc2)c2ccccc2[nH]c1=O -US20140128385A1,7,CN1CC(NC(=O)OC(C)(C)C)=NC(C)(c2cc(N)ccc2F)C1=O>>CN1CC(NC(=O)OC(C)(C)C)=NC(C)(c2cc(N)ccc2F)C1 -US20100197679A1,7,O=[N+]([O-])c1cc(Br)cnc1Br>>Nc1cc(Br)cnc1Br -US07670591B2,6,CNc1ccc(-c2nc3ccc(OC)cc3o2)cn1>>CNc1ccc(-c2nc3ccc(O)cc3o2)cn1 -US06022906,1,CC(C)(C(=O)c1ccc(Cl)cc1)N1CCOCC1.SCCCCCCS>>CC(C)(C(=O)c1ccc(SCCCCCCS)cc1)N1CCOCC1 -US07858640B2,6,COC(=O)Cc1cc(C)cc2nc(C)c(Cc3ccc(Cl)cc3)c(C)c12>>Cc1cc(CC(=O)O)c2c(C)c(Cc3ccc(Cl)cc3)c(C)nc2c1 -US07704994B2,1,COc1cc(Cl)nc2ccc(C)cc12.Oc1ccc2c(c1)CCN(C1CCC1)CC2>>COc1cc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc2ccc(C)cc12 -US20100256356A1,2,COc1ccc(Cn2ncc3c(Oc4ccc(N)cc4F)ccnc32)cc1.O=C(Cc1ccccc1)N=C=S>>COc1ccc(Cn2ncc3c(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4F)ccnc32)cc1 -US20120277237A1,3,C#CCCc1cnc2cc(F)c(F)cc2n1.FCc1cccc(Br)n1>>FCc1cccc(C#CCCc2cnc3cc(F)c(F)cc3n2)n1 -US08329729B2,1,N#Cc1ccc(COCCBr)cc1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>N#Cc1ccc(COCC[N+]23CCC(CC2)[C@@H](OC(=O)C2(c4ccccc4)CCCCCC2)C3)cc1 -US05952321,1,CI.C[C@H](NC(=O)OCc1ccccc1)c1ccc([N+](=O)[O-])cc1>>C[C@@H](c1ccc([N+](=O)[O-])cc1)N(C)C(=O)OCc1ccccc1 -US05023255,1,COC(=O)CCl.Cc1ccc(COc2cccc(N)c2)cc1>>COC(=O)CNc1cccc(OCc2ccc(C)cc2)c1 -US20020103203A1,6,C=CCc1cc(NC(=O)C(F)(F)F)cc(CC=C)c1C>>C=CCc1cc(N)cc(CC=C)c1C -US04374253,6,CC(=O)N(C1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1)c1cc([N+](=O)[O-])ccc1Cl>>O=C1CC(Nc2cc([N+](=O)[O-])ccc2Cl)=NN1c1c(Cl)cc(Cl)cc1Cl -US20130165412A1,9,FC(F)(F)c1cc(Cl)ncc1Cl.NN>>NNc1cc(C(F)(F)F)c(Cl)cn1 -US08486943B2,2,CC(C)(C)OC(=O)N1CC[C@H](O)[C@H]1CO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CC[C@H](O)[C@H]1COS(C)(=O)=O -US20120065224A1,1,Cc1[nH]c2ccnc(Cl)c2c1Cc1ccccc1.c1ccc2c(c1)CCNC2>>Cc1[nH]c2ccnc(N3CCc4ccccc4C3)c2c1Cc1ccccc1 -US20130005721A1,2,CCOC(=O)c1cc2cc(CO)ccn2c1C(C)C.CS(=O)(=O)Cl>>CCOC(=O)c1cc2cc(COS(C)(=O)=O)ccn2c1C(C)C -US06040457,8,CCCCc1ncc(CO)[nH]1>>CCCCc1ncc(C=O)[nH]1 -US20030153568A1,1,CCNC(=O)Nc1nc2ccc(Br)c(O)c2s1.CI>>CCNC(=O)Nc1nc2ccc(Br)c(OC)c2s1 -US20050148595A1,6,CC(C)(C)OC(=O)N1CCN(CC(c2cccc(C#N)c2)C2(O)CCCCC2)CC1>>N#Cc1cccc(C(CN2CCNCC2)C2(O)CCCCC2)c1 -US04160090,1,CN(C)Nc1c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c1[N+](=O)[O-].C[O-]>>COc1c(C(F)(F)F)cc([N+](=O)[O-])c(NN(C)C)c1[N+](=O)[O-] -US20100143455A1,1,C=CC(C)Br.O=c1[nH]ncn1-c1ccc(N2CCN(c3ccc(CSC4COC(Cn5cncn5)(c5ccc(F)cc5F)C4)cc3)CC2)cc1>>C=CC(C)n1ncn(-c2ccc(N3CCN(c4ccc(CSC5COC(Cn6cncn6)(c6ccc(F)cc6F)C5)cc4)CC3)cc2)c1=O -US06369110B1,3,CCOC(=O)CCC(C)=O.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)CCC(C)=Cc1ccccc1 -US08188133B2,9,Nc1ccc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)cc1F.S=C(Cl)Cl>>Fc1cc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)ccc1N=C=S -US20100144760A1,1,Cc1ccc(-c2ncccn2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CN)n1.N#Cc1c(C(F)(F)F)cc(Cl)nc1Cl>>Cc1ccc(-c2ncccn2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CNc2cc(C(F)(F)F)c(C#N)c(Cl)n2)n1 -US20090253679A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=Cc1c[nH]c2ncc(Br)cc12>>Cc1ccc(S(=O)(=O)n2cc(C=O)c3cc(Br)cnc32)cc1 -US04820705,6,COC(=O)C(C)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(C)cc1)C2>>Cc1ccc(S(=O)(=O)NC2Cc3ccc(C(C)C(=O)O)cc3C2)cc1 -US20070203155A1,1,COC(=O)COc1ccc(O)cc1C.ClCc1nc(-c2cccnc2)c(Br)s1>>COC(=O)COc1ccc(OCc2nc(-c3cccnc3)c(Br)s2)cc1C -US05266570,1,Clc1ncc(-c2ccccc2)cn1.NC1CCN(CC23CC(c4ccccc42)c2ccccc23)CC1>>c1ccc(-c2cnc(NC3CCN(CC45CC(c6ccccc64)c4ccccc45)CC3)nc2)cc1 -US20070276138A1,9,CO[C@@H](Cc1ccc(C#CCOc2ccc(C(=O)c3ccc(F)cc3)cc2)cc1)C(=O)O.NO>>CO[C@@H](Cc1ccc(C#CCOc2ccc(C(=NO)c3ccc(F)cc3)cc2)cc1)C(=O)O -US20080207616A1,1,COC(=O)CN.COC(=O)c1ccc([N+](=O)[O-])c(F)c1>>COC(=O)CNc1cc(C(=O)OC)ccc1[N+](=O)[O-] -US07112593B2,1,COCOc1ccc(I)cc1Cc1ccccc1.O=C1CCCN1>>COCOc1ccc(N2CCCC2=O)cc1Cc1ccccc1 -US06380218B1,2,N#Cc1cccc(Oc2ncccc2C(=O)O)c1.NCc1ccc(S(N)(=O)=O)cc1>>N#Cc1cccc(Oc2ncccc2C(=O)NCc2ccc(S(N)(=O)=O)cc2)c1 -US20110172416A1,2,CC(C)(C)OC(=O)N1CCCc2ccc(C(=O)O)cc2C1.OCC1CCN(c2ccncc2)CC1>>CC(C)(C)OC(=O)N1CCCc2ccc(C(=O)OCC3CCN(c4ccncc4)CC3)cc2C1 -US20040171604A1,1,Clc1ccc(-c2cc(CBr)no2)s1.c1c[nH]cn1>>Clc1ccc(-c2cc(Cn3ccnc3)no2)s1 -US06359134B1,6,COc1ccc2cc(S(=O)(=O)N3CCN(C(=O)c4ccc(CN(C(C)C)C(C)C)cc4)CC3)ccc2c1>>CC(C)N(Cc1ccc(C(=O)N2CCN(S(=O)(=O)c3ccc4cc(O)ccc4c3)CC2)cc1)C(C)C -US04059600,7,CCCCCC=CC=C/C=C/C(=O)OCC>>CCCCCCCC=C/C=C/C(=O)OCC -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cc(Cl)cc1Cl)[C@H]1CC[C@H](C)CC1>>C[C@H]1CC[C@H]([C@H](NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(Cl)cc(Cl)cc2Cl)C(=O)O)CC1 -US20030018055A1,2,CC(C)CC(C)CCCC(C)OC(=O)Cl.O=C(NC(CO)C(=O)OCc1ccccc1)OCc1ccccc1>>CC(C)CC(C)CCCC(C)OC(=O)OCC(NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1 -US05865857,1,CCCC(C)Nc1ccccc1.CCCCCCCBr>>CCCCCCCN(c1ccccc1)C(C)CCC -US20110312945A1,6,CCOC(=O)Cn1c(C)c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c1CCC(C)(C)C2>>Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCC(C)(C)C2 -US20140018533A1,3,CC(C)OC(=O)C1=C(N[C@@H]2CC[C@@H](O)CC2)OCC1=O.O=Cc1c[nH]c2ncccc12>>CC(C)OC(=O)C1=C(N[C@@H]2CC[C@@H](O)CC2)OC(=Cc2c[nH]c3ncccc23)C1=O -US20080167307A1,1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCO)cs1.Oc1ccc(Br)cc1>>CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(Br)cc2)cs1 -US07186745B2,1,CI.O=C1Cc2ccc(OCc3ccccc3)cc2N1>>CN1C(=O)Cc2ccc(OCc3ccccc3)cc21 -US04168964,8,Cc1[nH]c(Cc2ccccc2)nc1CO>>Cc1[nH]c(Cc2ccccc2)nc1C=O -US20130244945A1,6,CCNC(=O)C(O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C>>CCNC(=O)C(O)[C@@H](N)Cc1ccccc1 -US08569535B2,1,CCOC(=O)C1(NC(=O)c2cccc(C)c2OC(C)C)Cc2ccccc2C1.CI>>CCOC(=O)C1(N(C)C(=O)c2cccc(C)c2OC(C)C)Cc2ccccc2C1 -US20090306133A1,6,CN(C)CCOC1CCN(C(=O)OC(C)(C)C)CC1>>CN(C)CCOC1CCNCC1 -US20130190332A1,9,COC(=O)c1ccc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)n2c1.N>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(C(N)=O)cn4c3-c3ccccc3)cc2)CCC1 -US20050203078A1,7,C[C@H](NC(=O)c1ccc(N2CC=CCO2)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1>>C[C@H](NC(=O)c1ccc(N2CCCCO2)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1 -US20120029190A1,6,O=C(OCc1ccccc1)N1CCCc2oc(-c3ccccn3)nc2C1>>c1ccc(-c2nc3c(o2)CCCNC3)nc1 -US20150093327A1,1,C1CCC(N2CCCC2)CC1.CCI>>CC[N+]1(C2CCCCC2)CCCC1 -US20090233937A1,2,CC(C)(CO)C(=O)O.NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(F)c3)c21>>CC(C)(CO)C(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(F)c3)c21 -US06727264B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.Cn1c(C=O)cc2ccccc21>>CC(C)C(=O)Nc1cccc(C2CCN(Cc3cc4ccccc4n3C)CC2)c1 -US07902356B2,1,C=C(C)CN(CCO)Cc1ccccc1>>CC1(C)CN(Cc2ccccc2)CCO1 -USRE030199,1,CCO.Cc1ccc(N)cc1O>>CCNc1ccc(C)c(O)c1 -US05665719,6,COC(=O)c1ccc(O)cc1OC>>COc1cc(O)ccc1C(=O)O -US20070105919A1,2,Nc1nc(-c2ccco2)c(N2CCOCC2)s1.O=C(Cl)c1cccnc1>>O=C(Nc1nc(-c2ccco2)c(N2CCOCC2)s1)c1cccnc1 -US09102591B2,2,NCC(c1ccc(C(F)(F)F)nc1)C1CC1.O=C(O)c1cccc(Cl)c1Cl>>O=C(NCC(c1ccc(C(F)(F)F)nc1)C1CC1)c1cccc(Cl)c1Cl -US20070219183A1,7,CCOC(=O)c1cnn2c(-c3cccc([N+](=O)[O-])c3)ccnc12>>CCOC(=O)c1cnn2c(-c3cccc(N)c3)ccnc12 -US05965740,1,CC(=NN)c1ccc(C(F)(F)F)cc1.COC(C1=CN(C)CS1)c1ccccc1C=O>>COC(C1=CN(C)CS1)c1ccccc1C=NN=C(C)c1ccc(C(F)(F)F)cc1 -US05591846,1,CC(=O)OCC(CNC(=O)c1c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c(I)c(N2CCC(Br)C2=O)c1I)OC(C)=O.CC(=O)[O-]>>CC(=O)OCC(CNC(=O)c1c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c(I)c(N2CCC(OC(C)=O)C2=O)c1I)OC(C)=O -US20100160255A1,6,CC(C)(C)OC(=O)Nc1sc(-c2ccccn2)cc1C(=O)N1CCC(N2CCCC3(CC(=O)N(C4CCC4)C3=O)C2)CC1>>Nc1sc(-c2ccccn2)cc1C(=O)N1CCC(N2CCCC3(CC(=O)N(C4CCC4)C3=O)C2)CC1 -US20090118282A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(O)cc2)CC1 -US07326791B2,2,C1=CCNC1.Cc1cc(Br)ccc1C(=O)O>>Cc1cc(Br)ccc1C(=O)N1CC=CC1 -US20150079035A1,1,COC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.NC1CCCCC1>>COC(=O)c1ccc(NC2CCCCC2)c([N+](=O)[O-])c1 -US04411912,1,CC(C)C(Br)C(=O)O.Cc1ccc(N)c(F)c1>>Cc1ccc(N[C@H](C(=O)O)C(C)C)c(F)c1 -US04824839,2,CC(=O)Br.CS(=O)(=O)c1cc2c(cc1O)CCNCC2>>CC(=O)Oc1cc2c(cc1S(C)(=O)=O)CCNCC2 -US20120329830A1,7,COc1ccc(CNc2nc3ccc(-c4ncccc4C)cc3cc2/C=C(\C)C(=O)NCCC(C)(C)C)cc1>>COc1ccc(CNc2nc3ccc(-c4ncccc4C)cc3cc2CC(C)C(=O)NCCC(C)(C)C)cc1 -US20090111805A1,9,NO.O=Cc1c[nH]c2ncnc(Cl)c12>>ON=Cc1c[nH]c2ncnc(Cl)c12 -US20060058324A1,1,C1COCCN1.Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@@H]1CC[C@H](NC(=O)NCCCCl)CC1>>Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@@H]1CC[C@H](NC(=O)NCCCN2CCOCC2)CC1 -US20020193367A1,2,CC(C)(C)OC(=O)CC(=O)c1ccnc(C#N)c1.CC(C)(C)OC(=O)Nc1cc(N2CCC2)c(C(F)(F)F)cc1N>>CC(C)(C)OC(=O)Nc1cc(N2CCC2)c(C(F)(F)F)cc1NC(=O)CC(=O)c1ccnc(C#N)c1 -US20100249071A1,1,CC(C)N.COC(=O)c1cnc(F)c(C)c1>>COC(=O)c1cnc(NC(C)C)c(C)c1 -US05234946,3,CCCC[Sn](CCCC)(CCCC)c1ccsc1.O=Cc1cccc(COc2cccc(Br)c2)c1>>O=Cc1cccc(COc2cccc(-c3ccsc3)c2)c1 -US20100063021A9,9,CC(C)(C)OC(=O)N1CCC2(CCC(=O)c3ccccc32)CC1.NO>>CC(C)(C)OC(=O)N1CCC2(CCC(=NO)c3ccccc32)CC1 -US20150266878A1,7,COCC(=O)NC[C@H](Nc1cncc(-c2ccc3[nH]nc(F)c3c2)c1)c1ccccc1>>COCCNC[C@H](Nc1cncc(-c2ccc3[nH]nc(F)c3c2)c1)c1ccccc1 -US06214845B1,1,Cn1nnc(-c2ccc(CBr)cc2)n1.OC(c1ccc(OC(F)(F)F)cc1)(c1ccc(OC(F)(F)F)cc1)C1CCNCC1>>Cn1nnc(-c2ccc(CN3CCC(C(O)(c4ccc(OC(F)(F)F)cc4)c4ccc(OC(F)(F)F)cc4)CC3)cc2)n1 -US20050038016A1,8,CNCc1cccc(OCSC)c1.OO>>CNCc1cccc(OCS(C)=O)c1 -US20090324581A1,1,CC(C)CI.CCOC(=O)c1c[nH]nc1C(F)(F)F>>CCOC(=O)c1cn(CC(C)C)nc1C(F)(F)F -US06664291B2,1,BrCC1CC1.COc1ccc(Oc2c(Cl)cc([N+](=O)[O-])cc2Cl)cc1S(=O)O>>COc1ccc(Oc2c(Cl)cc([N+](=O)[O-])cc2Cl)cc1S(=O)(=O)CC1CC1 -US20030225268A1,1,Brc1cncc(OCc2ccccc2)c1.CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1cncc(OCc2ccccc2)c1 -US07642276B2,2,COC(=O)Cn1ncc2cc(-c3cc(C(=O)NC4CC4)ccc3C)ccc21.NCc1ccccc1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2CC(=O)NCc2ccccc2)c1 -US20080269233A1,6,CO[C@H]1CN(C(=O)[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2c2ccc(F)cc2F)CC[C@]1(OC)c1ccccc1>>CO[C@H]1CN(C(=O)[C@@H]2CNC[C@H]2c2ccc(F)cc2F)CC[C@]1(OC)c1ccccc1 -US09126998B2,7,O=[N+]([O-])c1nccc(F)c1O>>Nc1nccc(F)c1O -US06410538B2,6,COC(=O)c1ccc(C(=O)c2ccc(OC)c(OC)c2)cc1>>COc1ccc(C(=O)c2ccc(C(=O)O)cc2)cc1OC -US08809536B2,7,O=C([C@H]1COc2ccccc2O1)N1CCC[C@@H](c2ccccc2F)C1>>Fc1ccccc1[C@@H]1CCCN(C[C@H]2COc3ccccc3O2)C1 -US20130196964A1,1,C1CNCCN1.Cc1cc(-c2nc(-c3ccc(C(C)(C)C)cc3)no2)nn1Cc1ccnc(Cl)c1>>Cc1cc(-c2nc(-c3ccc(C(C)(C)C)cc3)no2)nn1Cc1ccnc(N2CCNCC2)c1 -US20080214621A1,6,COC(=O)CCCOc1ccc2cc(CC3CCN(C4CCCCC4)C3=O)ccc2c1>>O=C(O)CCCOc1ccc2cc(CC3CCN(C4CCCCC4)C3=O)ccc2c1 -US06107297,1,Clc1ccc(Cl)nn1.O=c1[nH]cc(C2c3ccccc3C=Cc3ccccc32)c(=O)[nH]1>>O=c1[nH]c(=O)n(-c2ccc(Cl)nn2)cc1C1c2ccccc2C=Cc2ccccc21 -US05556854,6,Cn1c(=O)[nH]c2c(c1=O)CN(CCCCOC1CCCCO1)CC2>>Cn1c(=O)[nH]c2c(c1=O)CN(CCCCO)CC2 -US20130150339A1,2,COc1cc(C(F)(F)F)ccc1-c1ncnc2cc(S(=O)(=O)Cl)ccc12.Nc1nccs1>>COc1cc(C(F)(F)F)ccc1-c1ncnc2cc(S(=O)(=O)Nc3nccs3)ccc12 -US08980879B2,2,CN1C=CC(N)=c2ccc3c4c([nH]c(=O)c-4c21)=CCN3c1ccc(F)cc1.O=S(=O)(Cl)c1ccccc1>>CN1C=CC(NS(=O)(=O)c2ccccc2)=c2ccc3c4c([nH]c(=O)c-4c21)=CCN3c1ccc(F)cc1 -US20150238500A1,1,CCOC(=O)c1[nH]c(C)c(C(=O)OCC)c1-c1ccccc1.OCCCBr>>CCOC(=O)c1c(-c2ccccc2)c(C(=O)OCC)n(CCCO)c1C -US20090186900A1,8,CC(=O)c1ccc(Sc2ccc(O)cc2)cc1.OO>>CC(=O)c1ccc(S(=O)c2ccc(O)cc2)cc1 -US20150203447A1,2,CCCCCCCCN=C=O.COC(=O)C(C)c1ccc(-c2cccc(O)c2)c(F)c1>>CCCCCCCCNC(=O)Oc1cccc(-c2ccc(C(C)C(=O)OC)cc2F)c1 -US20100113780A1,3,CCCc1nc(CC)c(Br)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.OB(O)c1ccc2c(c1)CCO2>>CCCc1nc(CC)c(-c2ccc3c(c2)CCO3)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US20130190347A1,2,Cc1ccc2c(c1)c1c(n2CCN)CCN(C)C1.O=C(O)C1CCCC1>>Cc1ccc2c(c1)c1c(n2CCNC(=O)C2CCCC2)CCN(C)C1 -US09145375B2,6,COC(=O)c1c(Cl)cc(Cl)c(OC)c1N>>COc1c(Cl)cc(Cl)c(C(=O)O)c1N -US05334712,1,NCCN(CCN)CCN.O=C1CCCCCCCCCCCCCC1>>NCCN(CCN)CCNC1CCCCCCCCCCCCCC1 -US20090076004A1,1,CCOC(=O)Cc1c(C(=O)OCC)c2cc(O)ccc2n1-c1ccc(N(C)C)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)Cc1c(C(=O)OCC)c2cc(Oc3ccc(C(F)(F)F)cc3)ccc2n1-c1ccc(N(C)C)cc1 -US08802697B2,7,COc1cc(OC)cc(-c2cnc3nc(Nc4c(C)cccc4[N+](=O)[O-])ncc3c2)c1>>COc1cc(OC)cc(-c2cnc3nc(Nc4c(C)cccc4N)ncc3c2)c1 -US08846684B2,2,NCCc1ccccc1.O=C(O)C1CCN(C(=O)c2cc3ccccc3n2Cc2ccc(Cl)cc2)CC1>>O=C(NCCc1ccccc1)C1CCN(C(=O)c2cc3ccccc3n2Cc2ccc(Cl)cc2)CC1 -US08952037B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.NC1CC(Oc2ncccc2Br)C1>>Cc1ccc(S(=O)(=O)NC2CC(Oc3ncccc3Br)C2)cc1 -US05373008,1,CN(C)C(=O)N(C)C.Nc1ccccc1N1CCOCC1>>CN(C)C(=Nc1ccccc1N1CCOCC1)N(C)C -US20100168103A1,2,CC(C)(C)N1CCNCC1.O=C(O)C1CCN(Cc2ccccc2)CC1>>CC(C)(C)N1CCN(C(=O)C2CCN(Cc3ccccc3)CC2)CC1 -US07985762B2,2,C=CCOC(=O)Cl.CCC[C@H](N)C(O)C(=O)NC1CC1>>C=CCOC(=O)NC(CCC)C(O)C(=O)NC1CC1 -US04321382,1,C1CCNC1.Cc1ccc(C23CC(=O)CCN2CCc2ccccc23)cc1>>Cc1ccc(C23CC(N4CCCC4)CCN2CCc2ccccc23)cc1 -US20070219198A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1ccccc1Cl>>CC(C)(C)OC(=O)N1CCC(Nc2ccccc2Cl)CC1 -US04052509,1,Cc1ccc(=O)[nH]c1.FC(F)(F)c1cccc(I)c1>>Cc1ccc(=O)n(-c2cccc(C(F)(F)F)c2)c1 -US20030008861A1,6,COC(=O)C1(C)C2CCCCC2CN1C(=O)OC(C)(C)C>>COC(=O)C1(C)NCC2CCCCC21 -US20070129346A1,7,CC(=O)OCC(C)(C)C(=O)N(C1CCC(=O)CC1)[C@H]1CCN(C(=O)OCc2ccccc2)C1>>CC(=O)OCC(C)(C)C(=O)N(C1CCC(O)CC1)[C@H]1CCN(C(=O)OCc2ccccc2)C1 -US06562828B1,1,CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)N1CCc2ccc(OCC3CCNCC3)cc2C1.ClCc1ccncc1>>CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)N1CCc2ccc(OCC3CCN(Cc4ccncc4)CC3)cc2C1 -US05885990,3,CCOC(=O)C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1ccc2c(C=O)c(O)ccc2c1>>CCOC(=O)C=Cc1c(O)ccc2cc(C#N)ccc12 -US06825199B2,1,CN1CCNCC1.COc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(F)cc32)cc1>>COc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(N4CCN(C)CC4)cc32)cc1 -US07902191B2,2,CN1CCN(C2CCc3cc(C(=O)O)ccc3C2)CC1.NCCN1CCCC1>>CN1CCN(C2CCc3cc(C(=O)NCCN4CCCC4)ccc3C2)CC1 -US20110003809A1,7,O=C(OCc1ccccc1)N1CCC(c2nc3cc([N+](=O)[O-])cnc3[nH]2)CC1>>Nc1cnc2[nH]c(C3CCN(C(=O)OCc4ccccc4)CC3)nc2c1 -US03952001,1,C=CCN(CC=C)C(=O)Cl.CCC(C)S(=O)c1nc[nH]n1>>C=CCN(CC=C)C(=O)n1cnc(S(=O)C(C)CC)n1 -US20080161251A1,4,CC(=O)CCC(C)=O.Nc1c[nH]nc1C(=O)Nc1ccc(F)cc1>>Cc1ccc(C)n1-c1c[nH]nc1C(=O)Nc1ccc(F)cc1 -US08063061B2,4,CCOC(=O)C(=O)CC(=O)c1ccc2c(c1)c1cc(-c3ccc(Br)cc3)c(=O)n(C)c1n2C.NN>>CCOC(=O)c1cc(-c2ccc3c(c2)c2cc(-c4ccc(Br)cc4)c(=O)n(C)c2n3C)[nH]n1 -US20090118327A1,7,CNC1=NCC(c2ccc([N+](=O)[O-])cc2)c2cc(Cl)ccc21>>CNC1=NCC(c2ccc(N)cc2)c2cc(Cl)ccc21 -US20100121048A1,6,COC(=O)c1ncn(C2Cc3ccccc3C2)c1-c1ccccc1>>O=C(O)c1ncn(C2Cc3ccccc3C2)c1-c1ccccc1 -US20120316161A1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1.CCCC(C(=O)OCC)c1c(C)nc2ccnn2c1Cl>>CCCC(C(=O)OCC)c1c(C)nc2ccnn2c1N1CC[C@H](NC(=O)OC(C)(C)C)C1 -US07884210B2,6,CCOC(=O)CSc1cnc(NC(=O)N(CCC(C)C)c2cccc(NC(C)=O)c2)s1>>CC(=O)Nc1cccc(N(CCC(C)C)C(=O)Nc2ncc(SCC(=O)O)s2)c1 -US08063046B2,2,COc1ccc(C(=O)O)cc1/C=C/c1ccc(OC(F)(F)F)cc1.Nn1cnnc1>>COc1ccc(C(=O)Nn2cnnc2)cc1/C=C/c1ccc(OC(F)(F)F)cc1 -US07419997B2,2,NC1CCCc2c1[nH]c1ccccc21.O=C(Cl)c1ccccc1>>O=C(NC1CCCc2c1[nH]c1ccccc21)c1ccccc1 -US20100004245A1,6,CCOC(=O)c1cncc(-c2ccc(N3CCC(Oc4cc(F)ccc4Br)CC3)nn2)c1>>O=C(O)c1cncc(-c2ccc(N3CCC(Oc4cc(F)ccc4Br)CC3)nn2)c1 -US20100197676A1,3,C#C[Si](C)(C)C.CC(C)(O)CO/N=C/c1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F>>C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(/C=N/OCC(C)(C)O)c(F)c2F)c(F)c1 -US20120114765A1,9,CC(Br)c1cc([N+](=O)[O-])c(Sc2ccc(Cl)cc2Cl)s1.N>>CC(N)c1cc([N+](=O)[O-])c(Sc2ccc(Cl)cc2Cl)s1 -US20090253671A1,1,COC(=O)c1cccc(NC(=O)[C@H](CO)NC(=O)OCc2ccccc2)c1>>COC(=O)c1cccc(N2CC(NC(=O)OCc3ccccc3)C2=O)c1 -US20090221555A1,1,CCN1C(=O)CCC(C)(C)c2ccc(N)cc21.NC(=O)[C@@H]1[C@H](Nc2nc(Cl)ncc2Cl)[C@H]2C=C[C@@H]1C2>>CCN1C(=O)CCC(C)(C)c2ccc(Nc3ncc(Cl)c(N[C@@H]4[C@H]5C=C[C@H](C5)[C@@H]4C(N)=O)n3)cc21 -US20070249670A1,2,CCCOc1cc(C)c(N=C=O)c(C)c1.COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1N)C1CCCCC1>>CCCOc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N[C@H](C(=O)OC)C2CCCCC2)c(C)c1 -US20070225300A1,2,CS(=O)(=O)Cl.OCC1Cc2nccnc2C1>>CS(=O)(=O)OCC1Cc2nccnc2C1 -US07214674B2,1,Cc1ncc2c(F)cccc2n1.OCCO>>Cc1ncc2c(OCCO)cccc2n1 -US20070299125A1,1,CCOC(=O)c1cc2ccccc2[nH]1.O=[N+]([O-])c1ccc(CBr)cc1>>CCOC(=O)c1cc2ccccc2n1Cc1ccc([N+](=O)[O-])cc1 -US20050075272A1,1,COc1ccc(N2C(=O)N([C@@H](C)c3ccccc3)c3nc(Cl)ncc3C2C)cc1.Nc1ccccc1>>COc1ccc(N2C(=O)N([C@@H](C)c3ccccc3)c3nc(Nc4ccccc4)ncc3C2C)cc1 -US05151534,2,CCCCCCCCC#CCC#CCC#CCS(=O)(=O)CC(=O)O.CO>>CCCCCCCCC#CCC#CCC#CCS(=O)(=O)CC(=O)OC -US20060135769A1,1,O=C(c1ccc(Cl)cc1)c1ccc2[nH]c(=O)cc(Cl)c2c1.c1c[nH]cn1>>O=C(c1ccc(Cl)cc1)c1ccc2[nH]c(=O)cc(-n3ccnc3)c2c1 -US20140163012A1,1,CC(C)(C)OC(=O)N1CCCc2oc3cc(Br)ccc3c2C1.O=C1CN(CCc2ccc(Cl)cc2)CCN1>>CC(C)(C)OC(=O)N1CCCc2oc3cc(N4CCN(CCc5ccc(Cl)cc5)CC4=O)ccc3c2C1 -US20150232472A1,1,Cc1c(C(F)(F)F)nc2ccc(Cl)nn12.Cn1nc(N2CCCC2)nc1CO>>Cc1c(C(F)(F)F)nc2ccc(OCc3nc(N4CCCC4)nn3C)nn12 -US20050010048A1,7,CON(C)C(=O)c1cc(Cn2cncn2)cc(C(=O)c2ccccc2)c1>>CON(C)C(=O)c1cc(Cc2ccccc2)cc(Cn2cncn2)c1 -US20090286785A1,1,N#Cc1cc(Oc2ccc(N)cc2)ccn1.Nc1nc(Cl)cc(Cl)n1>>N#Cc1cc(Oc2ccc(Nc3cc(Cl)nc(N)n3)cc2)ccn1 -US07001895B2,9,CS(=O)(=O)c1ccc(-c2cnn(CC(F)(F)F)c(=O)c2Cl)cc1.[N-]=[N+]=[N-]>>CS(=O)(=O)c1ccc(-c2cnn(CC(F)(F)F)c(=O)c2N=[N+]=[N-])cc1 -US07196199B2,1,COc1cccc2occc12.C[Sn](C)(C)Cl>>COc1cccc2oc([Sn](C)(C)C)cc12 -US04692515,9,CCCCCCCCCCO>>CCCCCCCCCC -US05747498,1,C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCCl)cc23)c1.C1COCCN1>>C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCN4CCOCC4)cc23)c1 -US07208598B2,1,CCCN.Clc1nc(Cl)c2ncn(C3CCOC3)c2n1>>CCCNc1nc(Cl)nc2c1ncn2C1CCOC1 -US07208142B2,3,CC(C)(C)c1ccc2c(c1)C(C)(C)CC2=O.CC1(C(=O)CC#N)CCCCC1>>CC1(C(=O)C(C#N)=C2CC(C)(C)c3cc(C(C)(C)C)ccc32)CCCCC1 -US06211199B1,4,COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5n4CCCCC#N)CC3)(c3ccccc3)C2)cc(OC)c1OC.[N-]=[N+]=[N-]>>COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5n4CCCCc4nnn[nH]4)CC3)(c3ccccc3)C2)cc(OC)c1OC -US20090111800A1,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C1CCC(N2CCC(Cc3ccc(Br)cc3Cl)C2=O)CC1>>Cn1cc(-c2ccc(CC3CCN(C4CCC(=O)CC4)C3=O)c(Cl)c2)cn1 -US07368578B2,3,CCOP(=O)(CC#N)OCC.COc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1nc(-c2ccco2)oc1C>>COc1cc(COc2nn(-c3ccccc3)cc2/C=C/C#N)ccc1OCc1nc(-c2ccco2)oc1C -US05374772,6,CCCCCCCCCCCCCCCCCCOc1cc(OCCCOc2ccc(S(C)=O)cc2)cc(C(=O)OC)c1>>CCCCCCCCCCCCCCCCCCOc1cc(OCCCOc2ccc(S(C)=O)cc2)cc(C(=O)O)c1 -US07183292B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCCCCCCCCO>>CN(CCCCCCCCO)C(=O)OC(C)(C)C -US20150284370A1,1,CCN(c1cc(-c2ccc(CO)nc2)cc(C(=O)NCc2c(C(C)C)cc(C)[nH]c2=O)c1C)C1CCOCC1.CN1CCCNCC1>>CCN(c1cc(-c2ccc(CN3CCCN(C)CC3)nc2)cc(C(=O)NCc2c(C(C)C)cc(C)[nH]c2=O)c1C)C1CCOCC1 -US08399436B2,1,Clc1ccc(CBr)c(OCc2ccccc2)c1.O=C(Nc1cc[nH]n1)c1c(F)cccc1F>>O=C(Nc1ccn(Cc2ccc(Cl)cc2OCc2ccccc2)n1)c1c(F)cccc1F -US06713489B2,2,NC1CC1.O=C(O)c1cnc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1>>O=C(NC1CC1)c1cnc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1 -US20050165055A1,1,CCOC(=O)CBr.Cc1ccc2[nH]c(C)c(Sc3ccc(Cl)cc3)c2c1>>CCOC(=O)Cn1c(C)c(Sc2ccc(Cl)cc2)c2cc(C)ccc21 -US20050222160A1,1,CCOc1cc(C2=NNCCC2)ccc1OC.Cc1nc(-c2cccnc2)sc1C(=O)Cl>>CCOc1cc(C2=NN(C(=O)c3sc(-c4cccnc4)nc3C)CCC2)ccc1OC -US20130274469A1,2,COC(=O)c1ccc(OCc2c(-c3ccccn3)noc2C)nc1.NC1CCOCC1>>Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NC2CCOCC2)cn1 -US06051712,6,COC(=O)c1cccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc3ccccc3c2)c1>>CC(C)(C)OC(=O)N1CCC(c2cccc(C(=O)O)c2)C(OCc2ccc3ccccc3c2)C1 -US20140171404A1,6,CC(C)(C)OC(=O)NC1CCN(C(=O)OCc2cc(Cl)cc(C#N)c2)CC1>>N#Cc1cc(Cl)cc(COC(=O)N2CCC(N)CC2)c1 -US05036075,1,CI.O=S1(=O)c2cccc3cccc(c23)N1CCCN1CC=C(c2c[nH]c3ccccc23)CC1>>Cn1cc(C2=CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)c2ccccc21 -US20070142362A1,3,C=O.CCCCC(=O)Cc1ccccc1>>C=C(C(=O)CCCC)c1ccccc1 -US20150148327A1,6,CCOC(=O)c1ccc(Oc2ccc(-c3cc(C)cc(Nc4nccc(C(F)(F)F)n4)c3)cn2)cc1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(Oc3ccc(C(=O)O)cc3)nc2)c1 -US20150025070A1,2,O=C(O)CN1CCC(C(=O)c2ccccc2)CC1.O=c1[nH]c(CNCC(F)F)nc2c1COCC2>>O=C(c1ccccc1)C1CCN(CC(=O)N(Cc2nc3c(c(=O)[nH]2)COCC3)CC(F)F)CC1 -US20100048537A1,1,N#Cc1ccc(F)cc1.OC1CNCc2occc21>>N#Cc1ccc(OC2CNCc3occc32)cc1 -US20150152113A1,2,COc1cccc(F)c1C1CC1CNc1cnnc(NN)c1Cl.O=C(Cl)CC(F)(F)F>>COc1cccc(F)c1C1CC1CNc1cnnc(NNC(=O)CC(F)(F)F)c1Cl -US07704995B2,2,CNC(=O)c1nc(-c2cccc(N)c2)cnc1N.O=C=NCc1ccccc1>>CNC(=O)c1nc(-c2cccc(NC(=O)NCc3ccccc3)c2)cnc1N -US07368458B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Br)cn1>>CC(C)(C)OC(=O)Nc1ccc(Br)cn1 -US08063046B2,9,COC(=O)c1ccc([N+](=O)[O-])c(C(=O)Nc2ccc(Cl)cc2)c1.N>>NC(=O)c1ccc([N+](=O)[O-])c(C(=O)Nc2ccc(Cl)cc2)c1 -US20110059043A1,1,COC(=O)c1cc(Cl)ccc1O.CSCCCl>>COC(=O)c1cc(Cl)ccc1OCCSC -US20150018546A1,6,Cc1ncnc2c1c(NCc1ccc(CNC(=O)OC(C)(C)C)cc1)cc(=O)n2OCc1ccccc1>>Cc1ncnc2c1c(NCc1ccc(CN)cc1)cc(=O)n2OCc1ccccc1 -US20110124618A1,6,CCOC(=O)c1cc(-c2cccc(C(F)(F)F)c2)n(-c2ccc(F)c(Cl)c2)n1>>O=C(O)c1cc(-c2cccc(C(F)(F)F)c2)n(-c2ccc(F)c(Cl)c2)n1 -US20110172245A1,1,CN1CCNCC1.Cc1ccc(Oc2ccc3nc(NC(=O)CCl)sc3c2)cc1NC(=O)c1cccc(C2(C#N)CC2)c1>>Cc1ccc(Oc2ccc3nc(NC(=O)CN4CCN(C)CC4)sc3c2)cc1NC(=O)c1cccc(C2(C#N)CC2)c1 -US20120270865A2,7,CC(=O)c1oc2ccc(OCc3ccccc3)cc2c1C>>Cc1c(C(C)O)oc2ccc(OCc3ccccc3)cc12 -US05624926,1,CCI.COc1cc2ncnc(N3CCC(n4c(=O)[nH]c5ccc([N+](=O)[O-])cc5c4=O)CC3)c2cc1OC>>CCn1c(=O)n(C2CCN(c3ncnc4cc(OC)c(OC)cc34)CC2)c(=O)c2cc([N+](=O)[O-])ccc21 -US20090233956A1,1,COc1cc2c(-c3cc4cccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(C)c2cc1OCCI.OC1CCNCC1>>COc1cc2c(-c3cc4cccnc4n3S(=O)(=O)c3ccc(C)cc3)cn(C)c2cc1OCCN1CCC(O)CC1 -US05872118,3,O=C(Cl)CCCc1ccccc1F>>O=C1CCCc2c(F)cccc21 -US20150266897A1,1,BrCc1cccc(I)c1.COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@@H](OCc2cccc(I)c2)CN1C(=O)OC(C)(C)C -US20090099184A1,2,CCOCCn1cc(C(=O)O)ccc1=O.NCc1ccc(Br)cc1OC(F)(F)F>>CCOCCn1cc(C(=O)NCc2ccc(Br)cc2OC(F)(F)F)ccc1=O -US07129294B2,2,C=CCOCCO.CC(Br)C(=O)Cl>>C=CCOCCOC(=O)C(C)Br -US09145380B2,7,NS(=O)(=O)c1ccccc1NS(=O)(=O)/C=C/c1ccccc1-c1ccc2cccc-2o1>>NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccccc1-c1ccc2cccc-2o1 -US20140371220A1,1,Cn1cc(-c2ccc(N3CCC(=O)CC3)nn2)cn1.Fc1ccc2c(c1)CCN2>>Cn1cc(-c2ccc(N3CCC(N4CCc5cc(F)ccc54)CC3)nn2)cn1 -US20150197511A1,1,CC(C)(C)OC(=O)Nc1ccc(O)cc1F.Fc1ccnc(Cl)c1>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(Cl)c2)cc1F -US20070293509A1,2,CC(O)(CN)C1CC1.O=C(O)c1cnc(Br)c(-c2ccc(Cl)cc2)n1>>CC(O)(CNC(=O)c1cnc(Br)c(-c2ccc(Cl)cc2)n1)C1CC1 -US20130035326A1,1,Fc1ccc(Br)cn1.NCCN1CCOCC1>>Brc1ccc(NCCN2CCOCC2)nc1 -US04558043,1,CCOC(CCl)OCC.Cc1ccc(O)cc1[N+](=O)[O-]>>CCOC(COc1ccc(C)c([N+](=O)[O-])c1)OCC -US05639780,3,C[Mg+].N#CCC1(CC=O)CC1>>CC(O)CC1(CC#N)CC1 -US08222248B2,7,O=C(O)c1c(Cl)cc(Cl)cc1Cl>>OCc1c(Cl)cc(Cl)cc1Cl -US05776983,9,O=C(O)c1ccc(CBr)cc1.[C-]#N>>N#CCc1ccc(C(=O)O)cc1 -US05859032,2,CC(C)=CCC/C(C)=C/COc1ccc(C(=O)O)cc1.COc1ccc(NCCN)cn1>>COc1ccc(NCCNC(=O)c2ccc(OC/C=C(\C)CCC=C(C)C)cc2)cn1 -US20140329803A1,6,CCOC(=O)N1CCCC(N2CCC(C)(C(=O)OCC)CC2)CC1>>CCOC(=O)N1CCCC(N2CCC(C)(C(=O)O)CC2)CC1 -US20090082372A1,2,COc1ccccc1C#Cc1ccc(OC(C)C)c(C(=O)O)c1.NC(CO)Cc1c[nH]c2cccnc12>>COc1ccccc1C#Cc1ccc(OC(C)C)c(C(=O)NC(CO)Cc2c[nH]c3cccnc23)c1 -US06417222B1,3,O=Cc1cc(Br)ccc1F.OB(O)c1ccsc1>>O=Cc1cc(-c2ccsc2)ccc1F -US05271864,7,CCCCCC1=CCC(C(=O)O)CC1>>CCCCCC1=CCC(CO)CC1 -US20110098323A1,3,CCOc1cc(C=O)ccc1O.O=C1CSC(=S)N1c1cccnc1>>CCOc1cc(C=C2SC(=S)N(c3cccnc3)C2=O)ccc1O -US20120095064A1,1,CC(=O)Nc1cc[nH]n1.Fc1cccc(Cl)c1CBr>>CC(=O)Nc1ccn(Cc2c(F)cccc2Cl)n1 -US20110112120A9,1,CC1(C)Cc2cc(B(O)O)ccc2O1.CCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(C)n(-c2ccc3c(c2)CC(C)(C)O3)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20140296306A1,7,CC(C)CC1C=C(C(=O)O)C1>>CC(C)CC1CC(C(=O)O)C1 -US08022068B2,2,CNOC.COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(=O)O)C[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(=O)N(C)OC)C[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21 -US20120108583A1,2,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(F)cccc4Cl)[nH]c23)O1.Cc1ccc(N)c(F)c1>>Cc1ccc(NC(=O)c2cc3nc(Nc4c(F)cccc4Cl)[nH]c3c3c2OC(C)(C)C3)c(F)c1 -US20090264418A1,2,CCOC(=O)c1cc2cc(C(=O)O)ccc2[nH]1.CN(C)C1CCNCC1>>CCOC(=O)c1cc2cc(C(=O)N3CCC(N(C)C)CC3)ccc2[nH]1 -US05843957,1,CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(O)c2)c2cccnc21.CCCI>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCCC)c2)c2cccnc21 -US20130324546A1,1,COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N.FC(F)(F)c1cnc(Cl)nc1Cl>>COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Cl)n1 -US06583154B1,3,Cc1nc(Cl)c2nc(-c3ccccc3)cc-2[nH]1.OB(O)c1cccnc1>>Cc1nc(-c2cccnc2)c2nc(-c3ccccc3)cc-2[nH]1 -US20150218129A1,1,O=C(C=Cc1ccc(OC2CCNCC2)cc1)N1CCOCC1.O=C1CCC1>>O=C(C=Cc1ccc(OC2CCN(C3CCC3)CC2)cc1)N1CCOCC1 -US20100210647A1,7,CS(=O)(=O)c1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1>>CS(=O)(=O)c1ccc(Oc2ccc(N)cc2)cc1 -US20080070954A1,2,COC(=O)CCCCCNC(=O)NC(=O)c1ccccc1.NO>>O=C(CCCCCNC(=O)NC(=O)c1ccccc1)NO -US06350749B1,1,CI.Cc1c[nH]c2c1C(=O)CC(c1ccccc1)C2>>Cc1cn(C)c2c1C(=O)CC(c1ccccc1)C2 -US07968568B2,1,CC(C)(C)OC(=O)N1CCC(N)CC1.COC(=O)c1cc(Cl)nc(Cl)n1>>COC(=O)c1cc(NC2CCN(C(=O)OC(C)(C)C)CC2)nc(Cl)n1 -US20090012125A1,3,C=CC(=O)OC(C)(C)C.COC(=O)c1ccc(Br)c(F)c1>>COC(=O)c1ccc(/C=C/C(=O)OC(C)(C)C)c(F)c1 -US06887896B1,7,CCOC(=O)C(F)=C(CC)c1cc2c(cc1OC)OC(C)(C)C=C2C>>CC/C(=C(\F)CO)c1cc2c(cc1OC)OC(C)(C)C=C2C -US05409939,8,CSCCC(CC(=O)O)NC(=O)CCCCc1ccc(C=NN)cc1.OO>>CS(=O)CCC(CC(=O)O)NC(=O)CCCCc1ccc(C=NN)cc1 -US07323570B2,3,N#Cc1ccc(F)c(Br)c1.OB(O)c1ccc(OC(F)(F)F)cc1>>N#Cc1ccc(F)c(-c2ccc(OC(F)(F)F)cc2)c1 -US07091237B2,6,CCCC[Sn](CCCC)(CCCC)c1cc(C)c(C2OCCO2)s1>>CCCC[Sn](CCCC)(CCCC)c1cc(C)c(C=O)s1 -US20070185183A1,3,CC1(C)CN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)c2ccc(Br)cc21.OB(O)c1ccc(C(F)(F)F)cc1>>CC1(C)CN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc21 -US20090156642A1,6,CN(Cc1cc(-c2cccnc2F)c(S(=O)(=O)c2nccs2)s1)C(=O)OC(C)(C)C>>CNCc1cc(-c2cccnc2F)c(S(=O)(=O)c2nccs2)s1 -US20110281884A1,6,CO[C@H]1CCN(c2c(C(C)Nc3ncnc4[nH]cnc34)cc(Cl)c3cncn23)C1>>CC(Nc1ncnc2[nH]cnc12)c1cc(Cl)c2cncn2c1N1CC[C@H](O)C1 -US06605626B2,6,COc1cc(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)cc(OC)c1>>COc1cc(O)cc(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)c1 -US08288316B2,2,CC(=O)Nc1nonc1N.CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1>>CC(=O)Nc1nonc1NC(=O)c1ccc(S(C)(=O)=O)cc1Cl -US20090227560A1,6,CCOC(=O)c1ncn([C@H]2CCCC[C@@H]2NC(=O)OCCOC)c1-c1ccccc1>>COCCOC(=O)N[C@H]1CCCC[C@@H]1n1cnc(C(=O)O)c1-c1ccccc1 -US20060025400A1,3,CCOC(=O)CCC[Zn+].O=C(N1CCc2ccc(Br)cc2C1)C(F)(F)F>>CCOC(=O)CCCc1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2 -US20100190688A1,6,Cc1ccc(S(=O)(=O)NCCCCC(NC(=O)C(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)C(C)C)C(=O)NC2CCCc3ccccc32)cc1>>CNC(C)C(=O)NC(C(=O)NC(CCCCNS(=O)(=O)c1ccc(C)cc1)C(=O)NC1CCCc2ccccc21)C(C)C -US07932262B2,1,CC(C)(C)OC(=O)N1CCC(Oc2c(Br)ccc3cnc(Cl)nc23)CC1.Nc1ccc(S(N)(=O)=O)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2c(Br)ccc3cnc(Nc4ccc(S(N)(=O)=O)cc4)nc23)CC1 -US20150018332A1,2,CN(C)CC1(F)CNC1.O=C(O)/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1>>CN(C)CC1(F)CN(C(=O)/C=C\n2cnc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C1 -US06384030B1,1,CC(N)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(OCC5COC(Cn6cncn6)(c6ccc(F)cc6F)O5)cc4)CC3)cc2)c1=O.O=Cc1ccccc1>>CC(NCc1ccccc1)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(OCC5COC(Cn6cncn6)(c6ccc(F)cc6F)O5)cc4)CC3)cc2)c1=O -US20080194579A1,1,COCCNCCOC.O=[N+]([O-])c1ccc(F)c(F)c1>>COCCN(CCOC)c1ccc([N+](=O)[O-])cc1F -US06232290B1,1,BrCCCCCCCBr.Sc1ccc(Br)cc1>>BrCCCCCCCSc1ccc(Br)cc1 -US08410089B2,7,Fc1cccc2cc[nH]c12>>Fc1cccc2c1NCC2 -US20140315898A1,2,Cc1cc(C)c(SCC(F)(F)F)cc1N.O=C=NCCCl>>Cc1cc(C)c(SCC(F)(F)F)cc1NC(=O)NCCCl -US20100080770A1,2,C=CCCCCCC(=O)N[C@H](C(=O)O)C(C)(C)C.C=Cc1cc2cc([C@@]3(OC)CN[C@H](C(=O)OC)C3)ccc2cc1OC>>C=CCCCCCC(=O)N[C@H](C(=O)N1C[C@](OC)(c2ccc3cc(OC)c(C=C)cc3c2)C[C@H]1C(=O)OC)C(C)(C)C -US20150259354A1,3,N#CCC#N.O=C(O)c1cnn(Cc2ccccc2)c1>>N#CC(C#N)=C(O)c1cnn(Cc2ccccc2)c1 -US07790715B2,1,CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCOc3ccc(F)cc3F)cc2)C(O)C1.COCCCN1C(=O)COc2ccc(CCl)cc21>>COCCCN1C(=O)COc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCCOc4ccc(F)cc4F)cc3)cc21 -US20050171347A1,2,CCOC(=O)N1CCC(N)CC1.O=S(=O)(Cl)c1ccc2ccccc2c1>>CCOC(=O)N1CCC(NS(=O)(=O)c2ccc3ccccc3c2)CC1 -US08399451B2,6,COC(=O)c1noc(CC(C)C)c1C(F)(F)F>>CC(C)Cc1onc(C(=O)O)c1C(F)(F)F -US20090105218A1,7,COC(=O)c1ccccc1NC(=O)c1cccc([N+](=O)[O-])c1>>COC(=O)c1ccccc1NC(=O)c1cccc(N)c1 -US20010018201A1,7,COC(=O)CCCC(=O)Nc1ccc(CCC(C)=O)cc1>>COC(=O)CCCC(=O)Nc1ccc(CCC(C)O)cc1 -US05441984,1,C=CCBr.CC(C)(C)c1ccccc1O>>C=CCOc1ccccc1C(C)(C)C -US05015640,1,CCOC(=N)N1Cc2ccccc2-c2ccccc2C1.O=C(Cl)c1cccc(F)c1>>CCOC(=NC(=O)c1cccc(F)c1)N1Cc2ccccc2-c2ccccc2C1 -US20100113782A1,1,CCn1ccc2ccc(NC(=O)c3ccc(Cl)nc3)cc21.O=C(OCc1ccccc1)c1ccc(N2CCNCC2)cc1>>CCn1ccc2ccc(NC(=O)c3ccc(N4CCN(c5ccc(C(=O)OCc6ccccc6)cc5)CC4)nc3)cc21 -US20060287291A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CN(Cc2cc([N+](=O)[O-])cc3ccoc23)CCN1>>CC1CN(Cc2cc([N+](=O)[O-])cc3ccoc23)CCN1C(=O)OC(C)(C)C -US20120157449A1,2,COCC(=O)O.N[C@@H]1CC[C@@H](CCN2CCCCC2c2ccoc3cccc2-3)CC1>>COCC(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2ccoc3cccc2-3)CC1 -US06756380B1,6,CCOC(=O)c1nc(SC)ncc1-c1ccccc1Cl>>CSc1ncc(-c2ccccc2Cl)c(C(=O)O)n1 -US04395410,2,CCCCCCC(C)N.O=C(Cl)CCCc1ccccc1>>CCCCCCC(C)NC(=O)CCCc1ccccc1 -US05057513,1,ClCc1cccnc1.O=C1C[C@]2(CCCC[C@H]2Cc2ccccc2)S(=O)(=O)CCN1>>O=C1C[C@]2(CCCC[C@H]2Cc2ccccc2)S(=O)(=O)CCN1Cc1cccnc1 -US08293768B2,2,Cc1cc(-n2cnn(CCC3CC3)c2=O)sc1C(=O)O.NCc1cccnc1>>Cc1cc(-n2cnn(CCC3CC3)c2=O)sc1C(=O)NCc1cccnc1 -US20110130384A1,3,CCOC(=O)c1cccc(B(O)O)c1.O=C1CCCc2ccc(OS(=O)(=O)C(F)(F)F)cc21>>CCOC(=O)c1cccc(-c2ccc3c(c2)C(=O)CCC3)c1 -US04086219,2,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.NC(=O)CC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)OCc1ccccc1 -US20090227583A1,1,Fc1ccc2c(c1)CCC2Nc1ccc2cc(Br)ccc2n1.Nc1cccc(C(F)(F)F)n1>>Fc1ccc2c(c1)CCC2Nc1ccc2cc(Nc3cccc(C(F)(F)F)n3)ccc2n1 -US20060264460A1,1,CN(C)Cc1cc(N)cc2c(Nc3cccc(Br)c3)c(C#N)cnc12.O=CCN1CCOCC1>>CN(C)Cc1cc(NCCN2CCOCC2)cc2c(Nc3cccc(Br)c3)c(C#N)cnc12 -US07494997B2,1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)c1ccc(CBr)c(Br)c1>>CCOC(=O)c1ccc(CN2CCN(C(=O)OC(C)(C)C)CC2)c(Br)c1 -US20140228358A1,1,CC(C)(O)COCc1cccc(Br)c1.N#CCC(C1CC1)n1cc(C(N)=O)c(N)n1>>CC(C)(O)COCc1cccc(Nc2nn(C(CC#N)C3CC3)cc2C(N)=O)c1 -US20060030612A1,3,CON(C)C(=O)c1cccc(C(F)(F)F)c1F.COc1ccc([Mg+])cc1>>COc1ccc(C(=O)c2cccc(C(F)(F)F)c2F)cc1 -US04921887,1,Nc1nc(CCl)cs1.c1ccc(C(OC2CCNCC2)c2ccccc2)cc1>>Nc1nc(CN2CCC(OC(c3ccccc3)c3ccccc3)CC2)cs1 -US20110178304A1,2,COc1cccc(C(=O)Cl)c1.NC1CCN(Cc2ccc3c(c2)NC(=O)CC3)CC1>>COc1cccc(C(=O)NC2CCN(Cc3ccc4c(c3)NC(=O)CC4)CC2)c1 -US20080194579A1,6,CN1CCN(c2ccc(NC(=O)OC(C)(C)C)cc2Cl)CC1>>CN1CCN(c2ccc(N)cc2Cl)CC1 -US20090069319A1,3,CNc1nc(Cl)ccc1[N+](=O)[O-].OB(O)c1ccc2ccccc2c1>>CNc1nc(-c2ccc3ccccc3c2)ccc1[N+](=O)[O-] -US20070185104A1,1,N#CCCN(CCO)C(=O)CCl>>N#CCCN1CCOCC1=O -US06939874B2,6,CCOC(=O)CCCCc1cc(OC)c(OC)cc1N>>COc1cc(N)c(CCCCC(=O)O)cc1OC -US20140336190A1,1,CCC1CCC(=O)N1.Cc1noc(C)c1-c1cc(I)c2nc(C3CC3)[nH]c2c1>>CCC1CCC(=O)N1c1cc(-c2c(C)noc2C)cc2[nH]c(C3CC3)nc12 -US07285557B2,2,COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1NCCN1CCCC1.O=CO>>COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1N(C=O)CCN1CCCC1 -US20060089356A1,2,CCOC(=O)c1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2Cl)n1C.NC1CCCCC1>>Cn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1Cl -US04127576,2,CN1[C@H]2CC[C@@H]1C[C@@H](O)C2.O=C(Cl)Oc1ccccc1>>CN1[C@H]2CC[C@@H]1C[C@@H](OC(=O)Oc1ccccc1)C2 -US20140005168A1,1,Cc1cncc(-c2cc3[nH]ncc3cn2)n1.Cn1cc(Br)cc(N2CCC[C@H](NC(=O)OC(C)(C)C)C2)c1=O>>Cc1cncc(-c2cc3c(cn2)cnn3-c2cc(N3CCC[C@H](NC(=O)OC(C)(C)C)C3)c(=O)n(C)c2)n1 -US20020038025A1,1,CCNCCO.CN(C(=O)Oc1ccc(Cl)cc1)c1ccc(OCCCCBr)cc1>>CCN(CCO)CCCCOc1ccc(N(C)C(=O)Oc2ccc(Cl)cc2)cc1 -US08815853B2,1,CC(C)OCCOS(C)(=O)=O.CC1(C)CCn2c(nc(Cl)cc2=O)N1>>CC(C)OCCN1c2nc(Cl)cc(=O)n2CCC1(C)C -US20090221555A1,1,CC1(C)CCC(=O)Nc2ccc(N)cc21.CNC(=O)c1cccc(Cl)c1Nc1nc(Cl)ncc1Cl>>CNC(=O)c1cccc(Cl)c1Nc1nc(Nc2ccc3c(c2)C(C)(C)CCC(=O)N3)ncc1Cl -US04921887,1,CCC(=O)Nc1nc(CCl)cs1.c1ccc(C(OC2CCNCC2)c2ccccc2)cc1>>CCC(=O)Nc1nc(CN2CCC(OC(c3ccccc3)c3ccccc3)CC2)cs1 -US04011236,2,CCO.O=C(Cl)c1ccc(C(=O)Cl)cc1>>CCOC(=O)c1ccc(C(=O)Cl)cc1 -US20030096856A1,9,COc1ccc(S(=O)(=O)Cl)cc1[N+](=O)[O-]>>COc1ccc(S(=O)[O-])cc1[N+](=O)[O-] -US05091432,2,CCOC(=O)CCn1cnc2c(=O)[nH]cnc21.CN1CCCC1CCN>>CN1CCCC1CCNC(=O)CCn1cnc2c(=O)[nH]cnc21 -US20070021414A1,1,CI.Oc1ccc(Br)nc1F>>COc1ccc(Br)nc1F -US20140275093A1,2,C[C@@H](N)c1ccc(C(=O)OC(C)(C)C)cc1.O=C(O)c1cc2ccccc2o1>>C[C@@H](NC(=O)c1cc2ccccc2o1)c1ccc(C(=O)OC(C)(C)C)cc1 -US20080207708A1,9,CC(C)COc1ccc(Cl)cc1Cc1nc(C(N)=O)cs1>>CC(C)COc1ccc(Cl)cc1Cc1nc(C#N)cs1 -US06242644B1,6,COC(=O)C(Nc1ccc(C(=N)NO)cc1)c1cc(Cl)cc(Cl)c1OCC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)COc1c(Cl)cc(Cl)cc1C(Nc1ccc(C(=N)NO)cc1)C(=O)O -US20040176361A1,1,CN1CCNCC1.O=c1[nH]c(Cl)cc2c(F)cc(F)cc12>>CN1CCN(c2cc3c(F)cc(F)cc3c(=O)[nH]2)CC1 -US20140113005A1,4,CCS(=O)(=O)N1CC=C(c2cnc(N)c(C(=O)O)n2)CC1.Cc1ccc(N)c(N)c1>>CCS(=O)(=O)N1CC=C(c2cnc(N)c(-c3nc4cc(C)ccc4[nH]3)n2)CC1 -US06008230,3,C#C[Si](C)(C)C.O=[N+]([O-])c1cccc2cc(Br)cnc12>>C[Si](C)(C)C#Cc1cnc2c([N+](=O)[O-])cccc2c1 -US04182764,6,COc1cc2c(c(Cl)c1Cl)C(=O)C(C)(c1ccc(F)cc1)C2>>CC1(c2ccc(F)cc2)Cc2cc(O)c(Cl)c(Cl)c2C1=O -US07858781B2,6,CC(C)(C)OC(=O)NC1CCN(C[C@@H]2CCCN3CCCC[C@H]23)CC1>>NC1CCN(C[C@@H]2CCCN3CCCC[C@H]23)CC1 -US20070281955A1,2,COc1cc(-c2nc3sccn3c2-c2ccnc(N[C@@H]3CCCNC3)n2)ccc1F.O=S(=O)(Cl)c1ccc(Cl)cc1>>COc1cc(-c2nc3sccn3c2-c2ccnc(N[C@@H]3CCCN(S(=O)(=O)c4ccc(Cl)cc4)C3)n2)ccc1F -US08853198B2,2,COc1ccc(SCCN)cc1.O=C(Cl)OCc1ccccc1>>COc1ccc(SCCNC(=O)OCc2ccccc2)cc1 -US05776937,6,COC(=O)CCN1CCN(CC2CN(C3CCN(C(=O)OC(C)(C)C)CC3)C(=O)O2)CC1>>CC(C)(C)OC(=O)N1CCC(N2CC(CN3CCN(CCC(=O)O)CC3)OC2=O)CC1 -US20070249607A1,6,COc1ccc(-c2ccc(C#N)cc2)cc1COCC1(c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1>>COc1ccc(-c2ccc(C#N)cc2)cc1COCC1(c2ccccc2)CCNCC1 -US20090105252A1,6,COC(=O)c1ccc(Br)cc1OC(F)(F)F>>O=C(O)c1ccc(Br)cc1OC(F)(F)F -US08327467B2,3,Brc1cccnc1.C=Cc1ccc(C(=O)OC(C)(C)C)c(Nc2ccc(F)cc2)c1>>CC(C)(C)OC(=O)c1ccc(/C=C/c2cccnc2)cc1Nc1ccc(F)cc1 -US20110098272A1,6,CC(C)(C)OC(=O)N1CCC(n2cnc(-c3ccc(F)cc3)c2-c2ccncn2)C1>>Fc1ccc(-c2ncn(C3CCNC3)c2-c2ccncn2)cc1 -US20150031668A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1ccc(C(=O)N[C@]2(c3ccc(OC(F)(F)F)c(F)c3)CCOc3cccnc32)cc1Br>>C=Cc1cc(C(=O)N[C@]2(c3ccc(OC(F)(F)F)c(F)c3)CCOc3cccnc32)ccc1C(=O)OC -US05436264,1,BrCC1CC1.OCCOc1ccccc1O>>OCCOc1ccccc1OCC1CC1 -US20140213589A1,2,CC(=O)OC(C)=O.CCc1ccc(Oc2ccc(NCCCN)cc2F)c(OCc2ccccc2)c1>>CCc1ccc(Oc2ccc(N(CCCN)C(C)=O)cc2F)c(OCc2ccccc2)c1 -US20080293743A1,3,CC(C)(C)OC(=O)N1CCc2cc(OS(=O)(=O)C(F)(F)F)ncc2C1.CC1(C)OB(c2ccc(C3CC3)nc2)OC1(C)C>>CC(C)(C)OC(=O)N1CCc2cc(-c3ccc(C4CC4)nc3)ncc2C1 -US20100113435A1,2,CCOC(=O)Cc1csc(N)n1.O=S(=O)(Cl)c1ccc(Cl)c2nonc12>>CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(Cl)c3nonc23)n1 -US07332497B2,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)c1cc2ccccc2n1C.Nc1ncnc2c1c(I)nn2CCCN1CCOCC1>>COc1cc(-c2nn(CCCN3CCOCC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C -US20090215778A1,1,C[C@@H](O)c1cc(F)cc(F)c1.C[C@@H]1CNCCN1>>C[C@@H](c1cc(F)cc(F)c1)N1CCN[C@H](C)C1 -US06359135B1,3,C#Cc1ccc2c(c1)C(C)(C)CCC2=O.CCOC(=O)Cc1ccc(I)cc1F>>CCOC(=O)Cc1ccc(C#Cc2ccc3c(c2)C(C)(C)CCC3=O)cc1F -US20130090323A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Nc1cc(N2CCOCC2)ncc1I>>CC(C)(C)OC(=O)N1CC=C(c2cnc(N3CCOCC3)cc2N)CC1 -US05994368,3,C=C[Sn](CCCC)(CCCC)CCCC.Cc1cc(OS(=O)(=O)C(F)(F)F)c2cccc(OCc3ccccc3)c2n1>>C=Cc1cc(C)nc2c(OCc3ccccc3)cccc12 -US04405357,2,CC(=O)Cl.COC(=O)C(C)(C)CO>>COC(=O)C(C)(C)COC(C)=O -US04908371,6,COCCn1ccc(=O)c(OCc2ccccc2)c1C>>COCCn1ccc(=O)c(O)c1C -US20150252044A1,3,NC(=O)c1ccc2cncc(Br)c2n1.OB(O)c1ccc(N2CCOCC2)cc1>>NC(=O)c1ccc2cncc(-c3ccc(N4CCOCC4)cc3)c2n1 -US08415368B2,8,Cc1c(CO)c[nH]c1-c1ccccc1F>>Cc1c(C=O)c[nH]c1-c1ccccc1F -US05374375,6,CCCC(C)OC(=O)c1ccc(OC(C)=O)cc1>>CCCC(C)OC(=O)c1ccc(O)cc1 -US06147097,6,COc1ccc(COCc2nc(C(C)C)c(Sc3cc(Cl)cc(Cl)c3)n2CC(C)=O)cc1>>CC(=O)Cn1c(CO)nc(C(C)C)c1Sc1cc(Cl)cc(Cl)c1 -US20080280911A1,1,Cc1cc(SC(C)(C)C)cc2c(Cl)c(C(N)=O)nnc12.Nc1cncc(F)c1>>Cc1cc(SC(C)(C)C)cc2c(Nc3cncc(F)c3)c(C(N)=O)nnc12 -US20070254867A1,6,COC(=O)C(C)(C)c1ccc2c(c1)NC(=O)c1ccc(-c3cccc4cnccc34)cc1N2>>CC(C)(C(=O)O)c1ccc2c(c1)NC(=O)c1ccc(-c3cccc4cnccc34)cc1N2 -US08173652B2,1,COC(=O)c1cc(O)ns1.Cc1onc(-c2ccc(F)cn2)c1CO>>COC(=O)c1cc(OCc2c(-c3ccc(F)cn3)noc2C)ns1 -US20090326229A1,6,COc1cccc2c1[nH]c1ncc(C)cc12>>Cc1cnc2[nH]c3c(O)cccc3c2c1 -US07638512B2,4,CC(C)(C)OO.OCC=Cc1ccccc1>>OC[C@H]1O[C@@H]1c1ccccc1 -US20130096135A1,2,CCCC(=O)Cl.O=C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCN(C(=O)CO)CC5)cn4)sc23)c(F)c1)NC1CC1>>CCCC(=O)OCC(=O)N1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)CC1 -US07544637B2,1,CCCS.N#Cc1c(F)cccc1OC(F)F>>CCCSc1cccc(OC(F)F)c1C#N -US20070259882A1,6,C[C@H](NC(=O)c1c(CN2CCN(CCCOC3CCCCO3)C(=O)C2)c(-c2ccccc2)nc2ccc(F)cc12)C1CCCCC1>>C[C@H](NC(=O)c1c(CN2CCN(CCCO)C(=O)C2)c(-c2ccccc2)nc2ccc(F)cc12)C1CCCCC1 -US05707991,2,CC(=O)C1CC(C(=O)OC(C)(C)C)NC1c1ccccc1.Cc1cccc(NC(=O)NCC(=O)O)c1>>CC(=O)C1CC(C(=O)OC(C)(C)C)N(C(=O)CNC(=O)Nc2cccc(C)c2)C1c1ccccc1 -US20100267709A1,3,CC1(C)OB(c2ccc3c(c2)[nH]c2c(C(N)=O)cnc(NC(C4CC4)C4CC4)c23)OC1(C)C.Clc1cccnn1>>NC(=O)c1cnc(NC(C2CC2)C2CC2)c2c1[nH]c1cc(-c3cccnn3)ccc12 -US20060111344A1,1,C1=COCCC1.O=c1ccc2c([C@@H](O)CBr)ccc(OCc3ccccc3)c2[nH]1>>O=c1ccc2c([C@H](CBr)OC3CCCCO3)ccc(OCc3ccccc3)c2[nH]1 -US04436726,2,CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)NCC(=O)O.N[C@@H](Cc1ccccc1)C(=O)O>>CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O -US20050096380A1,7,CCOC(=O)/C(F)=C(/C)c1cc2c(c(Br)c1OC)C(C)(C)CC=C2C(C)C>>COc1c(/C(C)=C(/F)CO)cc2c(c1Br)C(C)(C)CC=C2C(C)C -US07560463B2,1,NC(=O)c1ccc(Oc2ccc(C=O)cc2)nc1.c1ccc(CCC2CCCNC2)cc1>>NC(=O)c1ccc(Oc2ccc(CN3CCCC(CCc4ccccc4)C3)cc2)nc1 -US08049015B2,2,CCNCc1cc(C(F)(F)F)ccc1Br.O=C=NCc1ccccc1>>CCN(Cc1cc(C(F)(F)F)ccc1Br)C(=O)NCc1ccccc1 -US04753951,2,Cc1ccc(C(=O)O)s1.Nc1cnc2ccccc2c1N>>Cc1ccc(C(=O)Nc2cnc3ccccc3c2N)s1 -US08754242B2,7,O=C1CC(=O)C2C3C=CC(O3)C12>>O=C1CC(=O)C2C3CCC(O3)C12 -US05594023,2,COc1ccc(S(=O)(=O)Cl)c(OC)c1.NC1(c2ccccc2)C(=O)Nc2ccc(Cl)cc21>>COc1ccc(S(=O)(=O)N2C(=O)C(N)(c3ccccc3)c3cc(Cl)ccc32)c(OC)c1 -US20150246063A1,1,C1CC(c2nn[nH]n2)CCN1.O=Cc1ccc2c(C(F)(F)F)c(OC3CCC(C(F)(F)F)CC3)ccc2c1>>FC(F)(F)c1c(O[C@H]2CC[C@@H](C(F)(F)F)CC2)ccc2cc(CN3CCC(c4nn[nH]n4)CC3)ccc12 -US20150018422A1,3,C=CC(=O)OCC.COCOCc1cccc(Br)c1>>CCOC(=O)/C=C/c1cccc(COCOC)c1 -US20120108610A1,3,CNC(=O)c1nc(Br)c(C)n(-c2cccc(C(F)(F)F)c2)c1=O.N#Cc1ccc(-n2nccc2B(O)O)cc1>>CNC(=O)c1nc(-c2ccnn2-c2ccc(C#N)cc2)c(C)n(-c2cccc(C(F)(F)F)c2)c1=O -US20030004172A1,2,CN1CNCc2cc(C(=O)O)sc21.COc1ccc(CN)cc1>>COc1ccc(CNC(=O)c2cc3c(s2)N(C)CNC3)cc1 -US06878724B2,6,O=C(Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1 -US05670504,1,CCI.Cc1c(Sc2ccc(Cl)cc2)nn(-c2ccc(O)cc2)c(=O)c1C#N>>CCOc1ccc(-n2nc(Sc3ccc(Cl)cc3)c(C)c(C#N)c2=O)cc1 -US07803793B2,1,COc1ccc(O)cc1.O=C1C(S(=O)(=O)c2ccc(F)cc2)CCCCN1OC(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1ccc(Oc2ccc(S(=O)(=O)C3CCCCN(OC(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)cc1 -US20070225349A1,1,CC(C)I.COc1ccc(-c2n[nH]c3c(C(F)(F)F)cccc23)cc1>>COc1ccc(-c2nn(C(C)C)c3c(C(F)(F)F)cccc23)cc1 -US04188489,2,C=CC(=O)OOC(C)(N)CC.CS(=O)(=O)Cl>>C=CC(=O)OOC(C)(CC)NS(C)(=O)=O -US07786123B2,6,CCOC(=O)Cc1cc(OC)cc2c1CCCC2>>CCOC(=O)Cc1cc(O)cc2c1CCCC2 -US04820703,6,COc1ccc(CCc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc1>>Cc1nnc2n1-c1sc(CCc3ccc(O)cc3)cc1C(c1ccccc1Cl)=NC2 -US07279488B2,3,COc1ccnc(CCc2nc3cc(I)cnc3[nH]2)c1.O=S(=O)(NCCO)c1ccc(Br)cc1>>COc1ccnc(CCc2nc3cc(-c4ccc(S(=O)(=O)NCCO)cc4)cnc3[nH]2)c1 -US20050209268A1,1,CCCCc1nc2c(N)nc3ccccc3c2n1CCCCl.Sc1ccccc1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCSc1ccccc1 -US20110319393A1,2,O=C(O)CCN1CCC(OCc2ccc(C(F)(F)F)cc2)CC1.O=[N+]([O-])c1ccc(NC2CCNCC2)cc1C(F)(F)F>>O=C(CCN1CCC(OCc2ccc(C(F)(F)F)cc2)CC1)N1CCC(Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1 -US07691869B2,1,CS(=O)(=O)OCCn1ccc2c1nc(N)n1nc(-c3ccco3)nc21.O=C(c1ccc(F)cc1F)N1CCNCC1>>Nc1nc2c(ccn2CCN2CCN(C(=O)c3ccc(F)cc3F)CC2)c2nc(-c3ccco3)nn12 -US20080234199A1,3,CCC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(OC)c1.O=C(c1ccc(O)cc1)c1ccc(O)cc1>>CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)c(OC)c1 -US20150232445A1,6,COC(=O)N1c2ccc(-c3cnn(C4CCN(C(=O)OC(C)(C)C)CC4)c3)c(Oc3ccc(Cl)cc3C#N)c2CC[C@@H]1C>>COC(=O)N1c2ccc(-c3cnn(C4CCNCC4)c3)c(Oc3ccc(Cl)cc3C#N)c2CC[C@@H]1C -US20140303112A1,1,NCc1cccc(Cl)c1.Oc1nc(Cl)nc2nc[nH]c12>>Oc1nc(NCc2cccc(Cl)c2)nc2nc[nH]c12 -US20080318923A1,2,COc1ccc(S(=O)(=O)N2C(=O)C(NCC(=O)O)(c3ccccc3OC)c3cc(Cl)ccc32)c(OC(F)(F)F)c1.c1cc(N2CCNCC2)ccn1>>COc1ccc(S(=O)(=O)N2C(=O)C(NCC(=O)N3CCN(c4ccncc4)CC3)(c3ccccc3OC)c3cc(Cl)ccc32)c(OC(F)(F)F)c1 -US05719157,1,C1CNCCN1.CCOC(=O)c1c(CCl)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1>>CCOC(=O)c1c(CN2CCNCC2)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1 -US20100228054A1,7,CC(C)N(C)S(=O)(=O)NC(=O)c1ccc(F)c([N+](=O)[O-])c1Cl>>CC(C)N(C)S(=O)(=O)NC(=O)c1ccc(F)c(N)c1Cl -US20120202777A1,6,COc1cc(-c2ccc(F)cc2)ccc1CCC(C)(C(=O)NO)S(C)(=O)=O>>CC(CCc1ccc(-c2ccc(F)cc2)cc1O)(C(=O)NO)S(C)(=O)=O -US20130274469A1,2,CCN.Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1>>CCNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 -US20030069421A1,3,Nc1cccc(B(O)O)c1.O=[N+]([O-])c1cc(Br)ccc1F>>Nc1cccc(-c2ccc(F)c([N+](=O)[O-])c2)c1 -US20060264415A1,7,O=C(COCc1ccc(F)cc1)NCCCOc1ccc([N+](=O)[O-])cc1>>Nc1ccc(OCCCNC(=O)COCc2ccc(F)cc2)cc1 -US20020019558A1,2,O=C(Cl)C=Cc1cccc([N+](=O)[O-])c1.O=[N+]([O-])c1cccc(O)c1>>O=C(C=Cc1cccc([N+](=O)[O-])c1)Oc1cccc([N+](=O)[O-])c1 -US20090203665A1,3,C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1Cc2cc(Br)cnc2C1)C(F)(F)F.OB(O)c1ccc(F)cc1>>C[C@H](Oc1ccc(S(C)(=O)=O)cc1C(=O)N1Cc2cc(-c3ccc(F)cc3)cnc2C1)C(F)(F)F -US08802659B2,1,CC(C)(C)[C@@H]1CC[C@H](O)CC1.Cc1nc2cc(O)ccc2s1>>Cc1nc2cc(OC3CCC(C(C)(C)C)CC3)ccc2s1 -US06177443B1,1,CN(C)CCCl.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCCN(C)C)cc1 -US20070299077A1,7,CN1CCC2C1CCN2c1ccc([N+](=O)[O-])cc1>>CN1CCC2C1CCN2c1ccc(N)cc1 -US20030119827A1,2,CC(C)CC(O)C(=O)O.NC(=O)C(N)COCc1ccccc1>>CC(C)CC(O)C(=O)NC(COCc1ccccc1)C(N)=O -US07700657B2,6,C#C/C=C(\CC)c1cccc(O[Si](C)(C)C(C)(C)C)c1>>C#C/C=C(\CC)c1cccc(O)c1 -US20070293521A1,1,Fc1cnc(Cl)nc1Cl.NC(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Fc1cnc(Cl)nc1NC(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US05620987,6,CC(C)(C)NC(=O)[C@@H]1CCCCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1cc2ccccc2cc1OCc1ccccc1>>CC(C)(C)NC(=O)[C@@H]1CCCCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1cc2ccccc2cc1O -US20070208052A1,1,CCOC(=O)c1ccc(CCl)o1.CCc1nc2c(N)nc3cc(O)ccc3c2s1>>CCOC(=O)c1ccc(COc2ccc3c(c2)nc(N)c2nc(CC)sc23)o1 -US20070197577A1,6,COCCNC(=O)C(Cc1ccccc1)NC(=O)[C@H](Cc1csc2ccccc12)NC(=O)OC(C)(C)C>>COCCNC(=O)C(Cc1ccccc1)NC(=O)[C@@H](N)Cc1csc2ccccc12 -US20130029962A1,2,CN(CCO)c1ccc(N)cn1.O=C(Cl)Oc1ccccc1>>CN(CCO)c1ccc(NC(=O)Oc2ccccc2)cn1 -US20090181942A1,2,CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2NC1=NN.COCC(=O)Cl>>CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2NC1=NNC(=O)COC -US08815891B2,4,COCn1c(=O)c2c(c3ccc(CC#N)cc31)NCCC2.[N-]=[N+]=[N-]>>COCn1c(=O)c2c(c3ccc(Cc4nnn[nH]4)cc31)NCCC2 -US20140179702A1,2,C=CCN.O=C(NC(Cc1ccccc1)C(O)C(=O)O)c1cccnc1-n1ccc(-c2ccccc2)n1>>C=CCNC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1ccc(-c2ccccc2)n1 -US20140213586A1,1,COc1cccc(N)c1.O=Cc1ccc(O)nc1>>COc1cccc(N=Cc2ccc(O)nc2)c1 -US08575208B2,2,CC(C)(C)OC(=O)[C@@H]1CC(CN)(CC(=O)O)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@@H]1CC2(CNC(=O)C2)CN1C(=O)OC(C)(C)C -US08501780B2,2,NC(=O)c1cc(-c2ccccc2)cc2c(C3CCNCC3)n[nH]c12.O=C(Cl)c1ccccc1>>NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(C(=O)c4ccccc4)CC3)n[nH]c12 -US20150080412A1,7,CC(C)(C)c1ccc(C(=O)O)s1>>CC(C)(C)c1ccc(CO)s1 -US20120058999A1,1,CC(C)(C)OC(=O)CBr.Cc1cccc(Cl)c1S(=O)(=O)N1CCn2cccc2C1CO>>Cc1cccc(Cl)c1S(=O)(=O)N1CCn2cccc2C1COCC(=O)OC(C)(C)C -US08933105B2,2,CN(Cc1c[nH]c(-c2cccnc2C#N)c1)C(=O)OC(C)(C)C.COc1ccc(S(=O)(=O)Cl)cn1>>COc1ccc(S(=O)(=O)n2cc(CN(C)C(=O)OC(C)(C)C)cc2-c2cccnc2C#N)cn1 -US20130324547A1,2,CC(C)(C)OC(=O)N1CCC[C@H](N)C1.COc1ccc(C2CC(C(F)(F)F)n3nc(-c4ccnc(C(=O)O)c4)cc3N2)cc1OC>>COc1ccc(C2CC(C(F)(F)F)n3nc(-c4ccnc(C(=O)N[C@H]5CCCN(C(=O)OC(C)(C)C)C5)c4)cc3N2)cc1OC -US20090012125A1,2,COC(=O)c1ccc(CCC(=O)O)cc1.NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>COC(=O)c1ccc(CCC(=O)NC2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)cc1 -US20100048568A1,2,Cc1nc(-c2ccccn2)ncc1C(=O)O.Nn1ccc2cc(F)cnc21>>Cc1nc(-c2ccccn2)ncc1C(=O)Nn1ccc2cc(F)cnc21 -US20140303164A1,3,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(C#CC(C)(C)O[Si](C)(C)C(C)(C)C)ccc1Br.Cn1nc(N)c2c(Cl)ccc(B3OC(C)(C)C(C)(C)O3)c21>>Cn1nc(N)c2c(Cl)ccc(-c3ccc(C#CC(C)(C)O[Si](C)(C)C(C)(C)C)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)OC(C)(C)C)c21 -US04212867,2,CCOC(=O)C(=O)Cl.Cc1cc(C)cc(C(=O)NN)c1>>CCOC(=O)C(=O)NNC(=O)c1cc(C)cc(C)c1 -US06964966B2,1,CC1CN(Cc2ccccc2)CCC1=O.[NH4+]>>CC1CN(Cc2ccccc2)CCC1N -US20100272680A1,6,COC(=O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl>>O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl -US20110263571A1,2,Cc1cnc(N2CCNCC2)c(C)c1.O=C(O)c1ccc(Br)cc1[N+](=O)[O-]>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3[N+](=O)[O-])CC2)c(C)c1 -US20060079511A1,6,COc1cc2c(cc1C#N)C(c1ccccc1Cl)=NCC(=O)N2>>N#Cc1cc2c(cc1O)NC(=O)CN=C2c1ccccc1Cl -US08178699B2,6,COC(=O)c1sccc1NS(=O)(=O)c1ccc(C2CCCC2)cc1F>>O=C(O)c1sccc1NS(=O)(=O)c1ccc(C2CCCC2)cc1F -US20100331293A1,3,CC(C)c1c(Cl)nc2cc(F)ccc2c1Cl.CCCC[Sn](CCCC)(CCCC)c1cc(C)ccn1>>Cc1ccnc(-c2nc3cc(F)ccc3c(Cl)c2C(C)C)c1 -US20110020460A1,6,Fc1cc(-n2cnnn2)ccc1OCc1ccccc1>>Oc1ccc(-n2cnnn2)cc1F -US06291453B1,2,COC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(C)cc1.S=C=NCCCc1ccccc1>>COC(=O)[C@H](Cc1ccc(NC(=S)NCCCc2ccccc2)cc1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(C)cc1 -US06492541B2,2,CC(=O)Cl.N[C@@H](CCO)C(=O)O>>CC(=O)OCC[C@H](N)C(=O)O -US20100273744A1,3,O=C(Nc1ccn(Cc2cc(I)ccc2C(F)(F)F)n1)c1c(F)cccc1F.[Zn+]C1CC1>>O=C(Nc1ccn(Cc2cc(C3CC3)ccc2C(F)(F)F)n1)c1c(F)cccc1F -US20080193481A1,7,C=CCO[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1O[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OC(C)=O>>C=CCO[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1O[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1O -US04526981,6,COc1ccc(C(=O)c2c(CO[N+](=O)[O-])n(C(C)=O)c(=O)n2C(C)=O)cc1>>COc1ccc(C(=O)c2c(CO[N+](=O)[O-])[nH]c(=O)n2C(C)=O)cc1 -US07005440B1,1,CCOC(=O)CBr.Cc1cccc(C)c1O>>CCOC(=O)COc1c(C)cccc1C -US05214038,7,CCOC(=O)CN(c1ccncc1F)n1ccc2ccccc21>>OCCN(c1ccncc1F)n1ccc2ccccc21 -US20110207731A1,6,COCCCN(C)c1n[nH]c2ccc(C3OCCCO3)cc12>>COCCCN(C)c1n[nH]c2ccc(C=O)cc12 -US20050043291A1,1,CC(C)(C)OC(=O)NC1CNC1.Clc1ccc(I)cn1>>CC(C)(C)OC(=O)NC1CN(c2ccc(Cl)nc2)C1 -US04861897,1,ClCCCCOc1ccccc1/C=C/c1nc2ccccc2o1.c1c[nH]cn1>>C(=C/c1ccccc1OCCCCn1ccnc1)\c1nc2ccccc2o1 -US20020193389A1,1,N#Cc1ccccc1F.OCC1CCCNC1>>N#Cc1ccccc1N1CCCC(CO)C1 -US20120208840A1,4,CC(=O)c1nccc(C(C)C)c1F.CNN>>Cc1nn(C)c2c(C(C)C)ccnc12 -US05348955,6,O=C(O)C1CN(C(=O)OCc2ccccc2)CCN1C(=O)N(c1ccccc1)c1ccccc1>>O=C(O)C1CNCCN1C(=O)N(c1ccccc1)c1ccccc1 -US07872002B2,1,CN1CCCNCC1.O=c1c2c[nH]c3cc(F)c(F)cc3c-2nn1-c1ccccc1>>CN1CCCN(c2cc3[nH]cc4c(=O)n(-c5ccccc5)nc-4c3cc2F)CC1 -US20080287455A1,2,CCSc1ccc(S(C)(=O)=O)cc1C(=O)O.FC(F)(F)c1ccc(N2CCNCC2)cc1>>CCSc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1 -US20090286778A1,2,O=C(CC1CCNCC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2.O=C(Cl)c1cccnc1>>O=C(CC1CCN(C(=O)c2cccnc2)CC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2 -US04565659,2,CCCCCCCCCCCCCCCCN=C=O.CNCCO>>CCCCCCCCCCCCCCCCNC(=O)N(C)CCO -US04382958,1,CC(=O)Cc1ccc(OCCCO)cc1.NCC(O)c1cccc(C(F)(F)F)c1>>CC(Cc1ccc(OCCCO)cc1)NCC(O)c1cccc(C(F)(F)F)c1 -US20020107251A1,1,COc1ccc(N)cc1OC1CCCC1.O=[N+]([O-])c1cccnc1Cl>>COc1ccc(Nc2ncccc2[N+](=O)[O-])cc1OC1CCCC1 -US06211215B1,1,ClCc1coc(-c2cccs2)n1.Oc1cccc(CCCn2ccnc2)c1>>c1cc(CCCn2ccnc2)cc(OCc2coc(-c3cccs3)n2)c1 -US20150246063A1,6,COc1ccc2nc(C)ccc2c1>>Cc1ccc2cc(O)ccc2n1 -US06596719B1,2,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)C)cn2)nc(-c2ncccn2)nc1OCCN.O=S(=O)(Cl)c1cccs1>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)C)cn2)nc(-c2ncccn2)nc1OCCNS(=O)(=O)c1cccs1 -US20100210641A1,3,OB(O)C1=CCCC1.OC1CCCC(Nc2ccc3ncc(-c4ccnc(Cl)c4)n3c2)C1>>OC1CCCC(Nc2ccc3ncc(-c4ccnc(C5=CCCC5)c4)n3c2)C1 -US20050203087A1,2,COC(=O)Cl.COC(=O)c1sc(-c2cccc(N)c2)c(Br)c1OCC(=O)OC(C)(C)C>>COC(=O)Nc1cccc(-c2sc(C(=O)OC)c(OCC(=O)OC(C)(C)C)c2Br)c1 -US04931455,1,CCCCCCCCC(N)CC.CCc1ncnc(Cl)c1Cl>>CCCCCCCCC(CC)Nc1ncnc(CC)c1Cl -US20150266859A1,7,CCCC(=O)c1ccc(-n2cc(C(F)(F)F)cn2)nc1>>CCCC(O)c1ccc(-n2cc(C(F)(F)F)cn2)nc1 -US08575204B2,3,COc1ccc(NC(=O)c2ccc(Cl)nc2)cc1.Cc1ccc(C(=O)Nc2nccs2)cc1B1OC(C)(C)C(C)(C)O1>>COc1ccc(NC(=O)c2ccc(-c3cc(C(=O)Nc4nccs4)ccc3C)nc2)cc1 -US20060009517A1,2,CN.COC(=O)c1[nH]c2cccc3c2c1CCNC3=O>>CNC(=O)c1[nH]c2cccc3c2c1CCNC3=O -US20040077625A1,2,N#C[S-].Nc1cccc(F)c1>>NC(=S)Nc1cccc(F)c1 -US05578593,2,CC(C)(C)OC(=O)N1CCC2(CC1)CC(N)c1ccccc12.COC(=O)CS(=O)(=O)Cl>>COC(=O)CS(=O)(=O)NC1CC2(CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21 -US08957068B2,1,CC(C)[C@H]1COC(=O)N1c1ccnc(F)n1.Cc1cc(-c2cnc(C(C)N)nc2)ccc1F>>Cc1cc(-c2cnc(C(C)Nc3nccc(N4C(=O)OC[C@@H]4C(C)C)n3)nc2)ccc1F -US20150152096A1,1,CCOC(=O)C1=C(CBr)NC(c2cnccn2)=NC1c1ccc(F)cc1Cl.O=C(O)C1COCCN1>>CCOC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2cnccn2)=NC1c1ccc(F)cc1Cl -US07482457B2,2,CC(C)N1CCN(Cc2c(-c3ccccc3)nc3ccccc3c2C(=O)O)CC1.NN1CCCCCC1>>CC(C)N1CCN(Cc2c(-c3ccccc3)nc3ccccc3c2C(=O)NN2CCCCCC2)CC1 -US20150209358A1,2,CCn1cc(C(=O)O)c(=O)n(-c2ccc(F)cc2)c1=O.COc1cc(OC)c2nccc(Oc3ccc(N)cc3)c2c1>>CCn1cc(C(=O)Nc2ccc(Oc3ccnc4c(OC)cc(OC)cc34)cc2)c(=O)n(-c2ccc(F)cc2)c1=O -US07622471B2,1,C=O.CC1CN(C(=O)OC(C)(C)C)CC(C)N1>>CC1CN(C(=O)OC(C)(C)C)CC(C)N1C -US06300368B1,7,CC(C)(C)OC(=O)NCCOc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)NCCOc1ccc(N)cc1 -US07820654B2,5,COc1ccc(Nc2cc(-c3ccccc3)nc(N)n2)cc1Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(Nc2cc(-c3ccccc3)nc(NC(=O)C(F)(F)F)n2)cc1Cl -US07589199B2,7,COc1cc(N2CCN(C(=O)Cn3nc(C(C)=O)c(Cl)c3C)CC2)ccc1Cl>>COc1cc(N2CCN(C(=O)Cn3nc(C(C)O)c(Cl)c3C)CC2)ccc1Cl -US04200572,9,Cc1ccc(S(=O)(=O)OC[C@@H]2NC(=O)[C@@H]2N=[N+]=[N-])cc1>>Cc1ccc(S(=O)(=O)OC[C@@H]2NC(=O)[C@@H]2N)cc1 -US06329389B1,6,CCOC(=O)c1nc2ccccc2n(Cc2ccccc2)c1=O>>O=C(O)c1nc2ccccc2n(Cc2ccccc2)c1=O -US06211234B1,6,COc1ccc(C)c(C=O)c1>>Cc1ccc(O)cc1C=O -US20080139558A1,2,O=C(Cl)c1cccc(F)c1.O=c1cc(CNc2cccc(Cl)c2)c2cccc(F)c2[nH]1>>O=C(c1cccc(F)c1)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1 -US04632934,6,COc1ccc(Cc2ncc[nH]2)cc1>>Oc1ccc(Cc2ncc[nH]2)cc1 -US20150025057A1,1,CC(O)C(F)(F)F.O=C(O)c1ccc(Cl)nc1>>CC(Oc1ccc(C(=O)O)cn1)C(F)(F)F -US08093239B2,1,COc1cc(N2CCN(CCS(C)(=O)=O)CC2)ccc1N.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>COc1cc(N2CCN(CCS(C)(=O)=O)CC2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US20110124642A1,2,Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O.O=C(O)Cc1ccc(O)cc1>>O=C(Cc1ccc(O)cc1)Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O -US20140024650A1,6,COc1ccc(-n2cc(C#N)cn2)cc1F>>N#Cc1cnn(-c2ccc(O)c(F)c2)c1 -US05574064,2,CC(COc1ccc(C#N)cc1)NC(=O)[C@@H](N)C(C)C.COCC(C)OC(=O)Cl>>COCC(C)OC(=O)N[C@H](C(=O)NC(C)COc1ccc(C#N)cc1)C(C)C -US20080004269A1,7,CCCc1cc([N+](=O)[O-])cnc1Cc1ccnn1-c1ncccc1Br>>CCCc1cc(N)cnc1Cc1ccnn1-c1ncccc1Br -US20090029905A1,1,Cn1ccc(NC(=O)c2cc(O)cc(OC(CF)CF)c2)n1.O=C(c1ccc(Br)cn1)N1CCC1>>Cn1ccc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)nc3)cc(OC(CF)CF)c2)n1 -US08680299B2,3,O=Cc1cc(Cl)ccc1C(F)(F)F.OB(O)c1ccc(Cl)cc1>>O=Cc1cc(-c2ccc(Cl)cc2)ccc1C(F)(F)F -US20030119895A1,3,CSc1ccc(C=O)s1.O=C1Cc2ccccc2N1>>CSc1ccc(C=C2C(=O)Nc3ccccc32)s1 -US07569601B2,3,C=CC(=O)OC(C)(C)C.Oc1ccc(C(=C2CCCCCC2)c2ccc(Br)c(F)c2)cc1>>CC(C)(C)OC(=O)/C=C/c1ccc(C(=C2CCCCCC2)c2ccc(O)cc2)cc1F -US09090610B2,9,CC1(C)C(=O)Nc2nc(-c3nn(CC4CCCC4)c4ncc(F)cc34)nc(I)c21>>CC1(C)C(=O)Nc2nc(-c3nn(CC4CCCC4)c4ncc(F)cc34)ncc21 -US04368205,2,CC(=O)Cl.O=[N+]([O-])c1cccc2c1CCC2O>>CC(=O)OC1CCc2c1cccc2[N+](=O)[O-] -US04826857,1,CC(C)(COc1ccc(Cl)cc1)C1(C)CCC(CBr)O1.C[C@H]1CNC[C@@H](C)C1>>C[C@@H]1C[C@H](C)CN(CC2CCC(C)(C(C)(C)COc3ccc(Cl)cc3)O2)C1 -US20090042918A1,2,COc1cccc(C(=O)Cl)c1.Nc1cc(Cl)ccc1-c1nnn[nH]1>>COc1cccc(C(=O)Nc2cc(Cl)ccc2-c2nnn[nH]2)c1 -US20150133400A1,3,Cc1noc(C)c1-c1cnc2c(B(O)O)cn(CC3CCC(F)(F)CC3)c2c1.FC(F)c1ccc(Br)cc1>>Cc1noc(C)c1-c1cnc2c(-c3ccc(C(F)F)cc3)cn(CC3CCC(F)(F)CC3)c2c1 -US20110092423A1,2,Cn1ncc(Cl)c1-c1ncc(C(=O)O)o1.N[C@@H](Cc1cccc(F)c1)CN1C(=O)c2ccccc2C1=O>>Cn1ncc(Cl)c1-c1ncc(C(=O)N[C@@H](Cc2cccc(F)c2)CN2C(=O)c3ccccc3C2=O)o1 -US08492437B2,6,CC(C)(C)OC(=O)Cc1ccc(Oc2ccc(C(=O)Nc3ccc(Cl)c(Cl)c3)cc2)c(CNS(C)(=O)=O)c1>>CS(=O)(=O)NCc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)Nc2ccc(Cl)c(Cl)c2)cc1 -US08957070B2,2,Nc1cccc2c3c([nH]c12)C(=O)CCC3.O=S(=O)(Cl)c1cccs1>>O=C1CCCc2c1[nH]c1c(NS(=O)(=O)c3cccs3)cccc21 -US05418229,2,O=C(Cl)CCCCl.O=C1Nc2ccccc2Nc2ccccc21>>O=C1Nc2ccccc2N(C(=O)CCCCl)c2ccccc21 -US07238714B2,1,COc1cc(C)cc(O)c1.C[C@H](NC(=O)c1cc(Cl)cnc1Cl)c1ccc(C(=O)OC(C)(C)C)cc1>>COc1cc(C)cc(Oc2ncc(Cl)cc2C(=O)N[C@@H](C)c2ccc(C(=O)OC(C)(C)C)cc2)c1 -US20060122168A1,2,CC(C)(C(=O)O)C(=O)NCC(F)(F)C(F)(F)F.C[C@H]1Oc2ccc(F)cc2N(CCN2CCOCC2)C(=O)[C@H]1N>>C[C@H]1Oc2ccc(F)cc2N(CCN2CCOCC2)C(=O)[C@H]1NC(=O)C(C)(C)C(=O)NCC(F)(F)C(F)(F)F -US06777428B1,2,CN1CCC(C(=O)c2cccc(N)c2)CC1.O=C(Cl)c1ccc(F)c(F)c1>>CN1CCC(C(=O)c2cccc(NC(=O)c3ccc(F)c(F)c3)c2)CC1 -US04847268,1,ClC1CCCc2cccnc21.N#Cc1ccc(S)cc1>>N#Cc1ccc(SC2CCCc3cccnc32)cc1 -US20100087464A1,3,O=C1Cc2ccc(Nc3cccc(-c4nnc(-c5cccc(OC(F)(F)F)c5)[nH]4)c3)cc2N1.O=Cc1ccc[nH]1>>O=C1Nc2cc(Nc3cccc(-c4nnc(-c5cccc(OC(F)(F)F)c5)[nH]4)c3)ccc2C1=Cc1ccc[nH]1 -US20150175602A1,2,CN(C)C(=O)Cl.Fc1ccc(OC2CCN(c3nc4c(nc3NCC(F)F)CCNC4)CC2)c(F)c1>>CN(C)C(=O)N1CCc2nc(NCC(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2C1 -US20150252011A1,6,Cc1c(F)cccc1C1(C(F)F)N=C(NC(=O)c2ccccc2)OC2CC21>>Cc1c(F)cccc1C1(C(F)F)N=C(N)OC2CC21 -US20140112945A1,6,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccc(F)cc4)NC(=O)OC(C)(C)C)CC3)C(=O)C(C)(C)C2)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(F)cc4)CC3)C(=O)C(C)(C)C2)cc1OC -US20060223801A1,1,COC(=O)c1cc(Cl)c2cc(Cl)ccc2n1.Cc1[nH]c(C(=O)NC2CCNCC2)c(Cl)c1Cl>>COC(=O)c1cc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)CC2)c2cc(Cl)ccc2n1 -US20150018336A1,1,C=O.CC(C)(C)OC(=O)Nc1ncnc2c1c(I)nn2-c1ccc(N)cc1>>CNc1ccc(-n2nc(I)c3c(NC(=O)OC(C)(C)C)ncnc32)cc1 -US20120225865A1,2,COC(=O)[C@@H]1CC[C@@H](Oc2cc(C)nc(C)n2)CC1.NN>>Cc1cc(O[C@@H]2CC[C@@H](C(=O)NN)CC2)nc(C)n1 -US20100240654A1,6,COC(=O)C(Nc1ccc(C(=N)N)cc1)c1cc(OC)c(OC)cc1F>>COc1cc(F)c(C(Nc2ccc(C(=N)N)cc2)C(=O)O)cc1OC -US04777252,2,COc1cc2cnc(C(=O)O)cc2cc1OC.NN1CCNC1=O>>COc1cc2cnc(C(=O)NN3CCNC3=O)cc2cc1OC -US20090030018A1,2,CC(=O)OC(C)=O.CC(OCc1ncc[nH]1)c1cccc(-n2cnc3cc(CN)ccc32)c1>>CC(=O)NCc1ccc2c(c1)ncn2-c1cccc(C(C)OCc2ncc[nH]2)c1 -US20140249104A1,3,C#C[Si](CC)(CC)CC.NC1=N[C@](CF)(c2cc(Br)ccc2F)C[C@@H](C(F)(F)F)O1>>CC[Si](C#Cc1ccc(F)c([C@]2(CF)C[C@@H](C(F)(F)F)OC(N)=N2)c1)(CC)CC -US20080090806A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(Cc2ccccn2)C1=O>>N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(Cc2ccccn2)C1=O -US05691330,1,CC(=O)N1CCc2c(sc(C)c2CCBr)C1.Fc1ccc(-n2nc(C3CCNCC3)c3ccc(F)cc32)cc1>>CC(=O)N1CCc2c(sc(C)c2CCN2CCC(c3nn(-c4ccc(F)cc4)c4cc(F)ccc34)CC2)C1 -US20100076026A1,2,CCOC(=O)Cc1ccc(N=C=O)c(Cl)c1.Clc1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1>>CCOC(=O)Cc1ccc(NC(=O)N(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(Cl)c1 -US06348474B1,2,CO.Cc1n[nH]c2cc(C(=O)O)ccc12>>COC(=O)c1ccc2c(C)n[nH]c2c1 -US20130072679A1,3,CCS(=O)(=O)NCc1cncc(Br)c1.CN1C(=O)CCc2cc(B3OC(C)(C)C(C)(C)O3)cc(Cl)c21>>CCS(=O)(=O)NCc1cncc(-c2cc(Cl)c3c(c2)CCC(=O)N3C)c1 -US05580552,1,BrCc1ccccc1.COc1c(O)c2ccc(OC(C)=O)cc2oc1=O>>COc1c(OCc2ccccc2)c2ccc(OC(C)=O)cc2oc1=O -US20150099883A1,1,CC(C)(NC(=O)NOCc1ccccc1)c1ccccn1.CCI>>CCN(OCc1ccccc1)C(=O)NC(C)(C)c1ccccn1 -US20140378421A1,1,CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c(NC=O)c1.CN(CCCn1c(=O)[nH]c2cc(C=O)ccc21)[C@@H]1CC[C@@H](OC(=O)C(O)(c2cccs2)c2cccs2)CC1>>CN(CCCn1c(=O)[nH]c2cc(CNC[C@H](O[Si](C)(C)C(C)(C)C)c3ccc(O)c(NC=O)c3)ccc21)[C@@H]1CC[C@@H](OC(=O)C(O)(c2cccs2)c2cccs2)CC1 -US20110136902A1,6,C=CC[C@H](NC(=O)OC(C)(C)C)/C(C)=C/COC(=O)c1ccccc1>>C=CC[C@H](N)/C(C)=C/COC(=O)c1ccccc1 -US20080167314A1,9,Cc1cc(-c2nc3ccc(Cl)nn3c2-c2ccnc(N)c2)ccc1F>>Cc1cc(-c2nc3cccnn3c2-c2ccnc(N)c2)ccc1F -US20080275043A1,1,ClCCN1CCCCC1.O=C1C(Cc2ccc(-c3ccc(O)cc3)cc2Cl)CCN1C1CCCCC1>>O=C1C(Cc2ccc(-c3ccc(OCCN4CCCCC4)cc3)cc2Cl)CCN1C1CCCCC1 -US08716303B2,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.N#Cc1c(I)ccnc1Cl>>C=C(OCC)c1ccnc(Cl)c1C#N -US20090124618A1,1,C1CCNC1.CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(OCCCBr)cc2)C1>>CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(OCCCN3CCCC3)cc2)C1 -US20110224136A1,2,CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(-c4ccc(C(=O)O)cc4)cc3)o2)C1.Nc1ccccc1Cl>>CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(-c4ccc(C(=O)Nc5ccccc5Cl)cc4)cc3)o2)C1 -US20090253684A1,3,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(C(=O)N3CCC(F)(F)C3)c2)c1CCC(=O)OCC.OB(O)c1ccccc1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(C(=O)N3CCC(F)(F)C3)cc(-c3ccccc3)c2)c1CCC(=O)OCC -US08119800B2,1,CC(=O)OCBr.CCn1c(C(=O)c2cc(C)cc(C#N)c2)c(C(C)C)c(=O)[nH]c1=O>>CCn1c(C(=O)c2cc(C)cc(C#N)c2)c(C(C)C)c(=O)n(COC(C)=O)c1=O -US20150238558A1,6,COC(=O)c1ccc(CN(C(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)C)[C@H](C)c2ccc(F)cc2)cc1>>C[C@@H](C(=O)N[C@H](C(=O)N1Cc2ccccc2C[C@H]1C(=O)N(Cc1ccc(C(=O)O)cc1)[C@H](C)c1ccc(F)cc1)C(C)(C)C)N(C)C(=O)OC(C)(C)C -US07196200B2,2,CS(=O)(=O)Cl.OC1CCN(Cc2ccccc2)C1>>CS(=O)(=O)OC1CCN(Cc2ccccc2)C1 -US05618528,1,O=C(O)CNC(=O)c1ccc(OCc2ccccc2)cc1.Oc1c(F)c(F)c(F)c(F)c1F>>O=C(CNC(=O)c1ccc(OCc2ccccc2)cc1)Oc1c(F)c(F)c(F)c(F)c1F -US20060058326A1,1,CCC(C)Cc1nc(SC)nc(Cl)c1-c1c(F)cc(F)cc1F.C[O-]>>CCC(C)Cc1nc(SC)nc(OC)c1-c1c(F)cc(F)cc1F -US20090264485A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Cn1nccc1CCO>>Cc1ccc(S(=O)(=O)OCCc2ccnn2C)cc1 -US20150065522A1,4,CCc1c(C)[nH]c2c(C(=O)NNC(=O)c3ccccn3)cnn2c1=O>>CCc1c(C)[nH]c2c(-c3nnc(-c4ccccn4)o3)cnn2c1=O -US07612076B2,9,Clc1cc(N2CCN(C3CCCC3)CC2)ccn1.N>>Nc1cc(N2CCN(C3CCCC3)CC2)ccn1 -US05693320,1,C=C(C)C(=O)NC1=CC(C(=O)O)C(O)(C(C)=O)C=C1.Oc1ccccc1>>C=C(C)C(=O)NC1=CC(C(=O)Oc2ccccc2)C(O)(C(C)=O)C=C1 -US08404708B2,1,Cc1cc(F)ccc1-c1cc(N2CCC[C@H]2CO)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C1NC(=O)c2ccccc21>>Cc1cc(F)ccc1-c1cc(N2CCC[C@H]2CN2C(=O)c3ccccc3C2=O)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20100222318A1,2,CS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)O)n2)cc1.Nc1ccccc1>>CS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 -US08377944B2,6,CCOC(=O)c1sc2nc(CN3CCN(C(=O)OC(C)(C)C)CC3)[nH]c(=O)c2c1C>>Cc1c(C(=O)O)sc2nc(CN3CCN(C(=O)OC(C)(C)C)CC3)[nH]c(=O)c12 -US20040259912A1,1,COC(=O)c1cc([N+](=O)[O-])ccc1O.OC(c1ccc(C(F)(F)F)cc1)c1ccccc1Cl>>COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccc(C(F)(F)F)cc1)c1ccccc1Cl -US07405305B2,7,CC(C)(C)OC(=O)N(Cc1ccccc1)Cc1cccc2cc[nH]c12>>CC(C)(C)OC(=O)N(Cc1ccccc1)Cc1cccc2c1NCC2 -US20130140549A1,1,Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1.c1ccc(-n2c3ccccc3c3cc(-c4ccc5[nH]c6ccccc6c5c4)ccc32)cc1>>c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)ccc43)n2)cc1 -US20090221555A1,1,CCN1C(=O)CCC(C)(C)c2cc(N)ccc21.CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl>>CCN1C(=O)CCC(C)(C)c2cc(Nc3ncc(Cl)c(Nc4c(F)cccc4C(=O)NC)n3)ccc21 -US20100152441A1,2,CC(C)(C)OC(=O)NC1C2CN(CCO)CC21.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC1C2CN(CCOS(C)(=O)=O)CC21 -US20100105617A1,6,Cc1cc(=O)oc2cc(OCC(=O)NCCCCONC(=O)OC(C)(C)C)ccc12>>Cc1cc(=O)oc2cc(OCC(=O)NCCCCON)ccc12 -US09040522B2,2,Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O.NCCC1CCCCO1>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)NCCC3CCCCO3)cn2)c1O -US04350822,1,CCOC(=O)c1ccc(N)cc1.CS(=O)(=O)OCCCc1ccc(OCc2ccccc2)cc1>>CCOC(=O)c1ccc(NCCCc2ccc(OCc3ccccc3)cc2)cc1 -US20140113877A1,6,COc1ccc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)c(F)c1F>>COc1ccc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)c(F)c1F -US20020147334A1,6,CC(C)(C)OC(=O)NCCNc1ccccn1>>NCCNc1ccccn1 -US20040110951A1,1,COc1ccc(Oc2c(C)cc(C=O)cc2C)cc1C(C)C.NNC(N)=O>>COc1ccc(Oc2c(C)cc(C=NNC(N)=O)cc2C)cc1C(C)C -US06252076B1,1,C[C@H](N)c1ccccc1.OCCBr>>C[C@H](NCCO)c1ccccc1 -US20070049593A1,2,COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3N)[nH]c2c1.O=C(Cl)CCl>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3NC(=O)CCl)[nH]c2c1 -US05128448,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1cc2ccccc2s1>>CCOC(=O)/C=C/c1cc2ccccc2s1 -US20100240642A1,1,COCCBr.OCc1cc(O)cc(O)c1>>COCCOc1cc(O)cc(CO)c1 -US08044069B2,2,NC1CCOc2ccc(F)cc21.O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCCC(c2ccccc2)(c2ccccc2)C1=O)NC1CCOc2ccc(F)cc21 -US20100179173A1,2,CCc1cccc(NC(=O)N2CCc3nc(-c4ccc5c(c4)OCO5)nc(O)c3C2)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCc1cccc(NC(=O)N2CCc3nc(-c4ccc5c(c4)OCO5)nc(OS(=O)(=O)c4ccc(C)cc4)c3C2)c1 -US06982348B2,2,NC(Cc1cccc(Oc2ccccc2)c1)C(O)c1ccc(F)cc1.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)NC(Cc1cccc(Oc2ccccc2)c1)C(O)c1ccc(F)cc1 -US06235731B1,6,CC(C)(C)OC(=O)N1CCN(CCCc2ccccc2)C(=O)C1>>O=C1CNCCN1CCCc1ccccc1 -US20040110742A1,2,CS(=O)(=O)Cl.OCCc1ccc(N2CCOCC2)cc1>>CS(=O)(=O)OCCc1ccc(N2CCOCC2)cc1 -US06727264B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccc(Br)cc3)CC2)c1.NNc1ccccc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCc3c(-c4ccc(Br)cc4)[nH]c4ccccc34)CC2)c1 -US20120258952A1,1,CC(C)(C)OC(=O)N1CC[C@H](OS(C)(=O)=O)[C@H](F)C1.CCc1nn(Cc2cn[nH]c2)c2cccc(NC(=O)c3cnc4ccccn34)c12>>CCc1nn(Cc2cnn([C@@H]3CCN(C(=O)OC(C)(C)C)C[C@H]3F)c2)c2cccc(NC(=O)c3cnc4ccccn34)c12 -US07732463B2,1,Cc1ccc(S)c(C)c1.FC(F)(F)c1ccc(I)c(Br)c1>>Cc1ccc(Sc2ccc(C(F)(F)F)cc2Br)c(C)c1 -US20140107085A1,1,COC(=O)c1ccccc1OS(=O)(=O)C(F)(F)F.Nc1ccccc1>>COC(=O)c1ccccc1Nc1ccccc1 -US04071621,1,CC(C)(C)OC(=O)CCl.CCSCCN>>CCSCCNCC(=O)OC(C)(C)C -US20100249110A1,1,CI.COc1ccc(CN2CCc3n[nH]c4nc(SC)nc2c34)cc1>>COc1ccc(CN2CCc3nn(C)c4nc(SC)nc2c34)cc1 -US07129239B2,2,Nc1c(Cl)ncnc1Nc1ccc(Cl)cc1.O=C(Cl)c1ccc(Cl)cc1Cl>>O=C(Nc1c(Cl)ncnc1Nc1ccc(Cl)cc1)c1ccc(Cl)cc1Cl -US20090029947A1,1,COc1cccc(O)c1.O=C1N[C@@]2(CC[C@@H](c3ccc(CCCO)cc3)C2)CO1>>COc1cccc(OCCCc2ccc([C@@H]3CC[C@]4(COC(=O)N4)C3)cc2)c1 -US04207341,2,CCOC(=O)Cc1ccc(CCN)cc1.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)Cc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1 -US20090286778A1,1,Clc1ncc(Cl)c(Cl)n1.Nc1cccc(CCCc2cccc(N)c2)c1>>Nc1cccc(CCCc2cccc(Nc3nc(Cl)ncc3Cl)c2)c1 -US20100016371A1,1,CC(C)Cc1c[nH]c2cc(Cl)ccc12.CCOC(=O)c1ccc(Br)s1>>CCOC(=O)c1ccc(-n2cc(CC(C)C)c3ccc(Cl)cc32)s1 -US08486967B2,1,CC(C)(C)OC(=O)N1CCC(=O)C(F)C1.Nc1nc2c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cccn2n1>>CC(C)(C)OC(=O)N1CCC(Nc2nc3c(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)cccn3n2)C(F)C1 -US07151111B2,1,COC(=O)[C@H]1CC(=O)N(c2ccc(O)cc2)C1.OCc1cccc(F)c1>>COC(=O)[C@H]1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1 -US20060041128A1,1,Cc1noc2nc(CC(C)C)[nH]c(=O)c12.Fc1cccc(CBr)c1>>Cc1noc2nc(CC(C)C)n(Cc3cccc(F)c3)c(=O)c12 -US20150080326A1,3,Clc1cncc(Cl)n1.OB(O)c1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(-c2cncc(Cl)n2)cc1 -US07776875B2,2,CNC.Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OCC(C)(C)C(=O)O)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OCC(C)(C)C(=O)N(C)C)C12C(=O)Nc1cc(Cl)ccc12 -US04293557,2,NCCCOc1cccc(CN2CCCCC2)c1.O=C[O-]>>O=CNCCCOc1cccc(CN2CCCCC2)c1 -US04929624,1,CC(C)(O)CN.O=[N+]([O-])c1cnc2ccccc2c1Cl>>CC(C)(O)CNc1c([N+](=O)[O-])cnc2ccccc12 -US20070270475A1,6,COC[C@H]1C[C@@](Cc2cscn2)(C(=O)OC(C)(C)C)N(C(=O)c2ccc(C(C)(C)C)c(OC)c2)[C@H]1c1ncc(C)s1>>COC[C@H]1C[C@@](Cc2cscn2)(C(=O)O)N(C(=O)c2ccc(C(C)(C)C)c(OC)c2)[C@H]1c1ncc(C)s1 -US07906546B2,4,COC(=O)C(F)(C1CCCC(=O)C1)S(=O)(=O)c1ccccc1.NNc1ccc(Cl)cc1>>COC(=O)C(F)(C1CCc2c([nH]c3ccc(Cl)cc23)C1)S(=O)(=O)c1ccccc1 -US20020038053A1,7,O=C(CBr)c1ccccc1>>O[C@@H](CBr)c1ccccc1 -US06630504B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(Oc2ccc(OC(F)(F)F)cc2)c(C2CCCN2)c1>>CC(C)(C)OC(=O)N1CCCC1c1cc([N+](=O)[O-])ccc1Oc1ccc(OC(F)(F)F)cc1 -US20070249670A1,6,CCCc1cc(C)c(NC(=O)Nc2cc(F)ccc2C(=O)N[C@H](C(=O)OC)C2CCCCC2)c(C)c1>>CCCc1cc(C)c(NC(=O)Nc2cc(F)ccc2C(=O)N[C@H](C(=O)O)C2CCCCC2)c(C)c1 -US07635715B2,2,CC(C)(C)OC(=O)CN.CCOC(=O)C1=C(O)c2cc(F)c(F)cc2C2(CCOCC2)C1=O>>CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2cc(F)c(F)cc2C2(CCOCC2)C1=O -US20110105566A1,1,CCCCCCO.Cn1nnnc1C(=NOCc1cccc(Br)n1)c1ccccc1>>CCCCCCOc1cccc(CON=C(c2ccccc2)c2nnnn2C)n1 -US20070037787A1,1,C1CN2CCN1CC2.O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(OCc3ccc(CBr)cc3)cc2)N1c1ccc(F)cc1>>O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(OCc3ccc(C[N+]45CCN(CC4)CC5)cc3)cc2)N1c1ccc(F)cc1 -US20080004302A1,7,CNC(=O)c1cc(OC)cc(/C=C/C(=O)OC)n1>>CNC(=O)c1cc(OC)cc(CCC(=O)OC)n1 -US08217032B2,3,COc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(OS(=O)(=O)C(F)(F)F)ccc2c1.OB(O)c1ccc(F)cc1>>COc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(F)cc3)ccc2c1 -US20090047244A1,6,CCOC(=O)[C@@]12C[C@H]1C=CCCCCN(C)C(=O)N[C@@H](CCOc1cc(-c3nc(C(C)C)cs3)nc3c(C)c(OC)ccc13)C(=O)N2>>COc1ccc2c(OCC[C@@H]3NC(=O)N(C)CCCCC=C[C@@H]4C[C@@]4(C(=O)O)NC3=O)cc(-c3nc(C(C)C)cs3)nc2c1C -US20100004238A1,1,BrCC1CC1.O=[N+]([O-])c1ccc(Oc2cccc3[nH]ccc23)c(Cl)c1>>O=[N+]([O-])c1ccc(Oc2cccc3c2ccn3CC2CC2)c(Cl)c1 -US20080269193A1,1,BrCC1CC1.CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C#N)c(NC4CCC(N)CC4)c3)c2C1>>CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C#N)c(NC4CCC(NCC5CC5)CC4)c3)c2C1 -US06936602B1,2,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3C(=O)CNC(C)=O)cc1.CN(Cc1ccc(N)cc1)C1CCOCC1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN(C)C4CCOCC4)cc2)CCN3C(=O)CNC(C)=O)cc1 -US20090270361A1,2,Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1C(=O)Cl.N#Cc1ccc(CN)cn1>>Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1C(=O)NCc1ccc(C#N)nc1 -US08173682B2,9,CCc1cc(C(=O)O)c(C)nc1OC.N>>CCc1cc(C(N)=O)c(C)nc1OC -US20110071129A1,1,Fc1ccc(Br)cn1.c1ccc(CN2CCC3(CCNC3)C2)cc1>>Fc1ccc(N2CCC3(CCN(Cc4ccccc4)C3)C2)cn1 -US20090048258A1,2,CCOc1ccc(C(=O)CCC(=O)O)cc1OCC.Nc1ccc(CN2CCOCC2)c(-c2ccccc2)c1>>CCOc1ccc(C(=O)CCC(=O)Nc2ccc(CN3CCOCC3)c(-c3ccccc3)c2)cc1OCC -US09133168B2,2,C[C@@H]1Cc2ccccc2N1.Cn1c(CC(=O)[O-])nc(N2CCOCC2)c(F)c1=O>>C[C@@H]1Cc2ccccc2N1C(=O)Cc1nc(N2CCOCC2)c(F)c(=O)n1C -US20040014968A1,3,COC(=O)C(=O)Cl.CSc1ccccc1Cl>>COC(=O)C(=O)c1ccc(SC)c(Cl)c1 -US20060009456A1,6,C=CCOc1ccc([C@H](C)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)c(C)c1C>>C=CCOc1ccc([C@H](C)N2C[C@@H]3C[C@H]2CN3)c(C)c1C -US20040058978A1,6,CC(C)(C)OC(=O)Nc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1>>Nc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1 -US20120245137A1,6,O=S(=O)(c1cccc(C(F)(F)F)c1)C1CCC2(CC1)OCCO2>>O=C1CCC(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 -US07241458B1,9,Cc1cc(C)c(Nc2nc(Cl)nc(Nc3ccc(C#N)cc3)n2)c(C)c1.N>>Cc1cc(C)c(Nc2nc(N)nc(Nc3ccc(C#N)cc3)n2)c(C)c1 -US20120094997A1,2,CC(C)(C)C(=O)Cl.COC(=O)c1ccc2ccn(CCCN)c(=O)c2c1>>COC(=O)c1ccc2ccn(CCCNC(=O)C(C)(C)C)c(=O)c2c1 -US07230024B2,1,CC(C)N.CCOC(=O)c1nn(-c2ccccc2Cl)c(Br)c1C=O>>CCOC(=O)c1nn(-c2ccccc2Cl)c(Br)c1CNC(C)C -US20030176441A1,2,Cc1ccc(C(=O)Cl)cc1.Nc1ccccc1N1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>Cc1ccc(C(=O)Nc2ccccc2N2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)cc1 -US03962443,6,CCOC(=O)c1cn(Cc2ccccc2)c2nc(N3CCNCC3)ncc2c1=O>>O=C(O)c1cn(Cc2ccccc2)c2nc(N3CCNCC3)ncc2c1=O -US07132436B2,2,Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Cl.Nc1nc(-c2cc([N+](=O)[O-])ccc2Cl)cs1>>Cc1cc(Cl)cc(Cl)c1S(=O)(=O)Nc1nc(-c2cc([N+](=O)[O-])ccc2Cl)cs1 -US20150045339A1,7,CC(C)(C)OC(=O)N1CCCC(Nc2cccc([N+](=O)[O-])c2)C1>>CC(C)(C)OC(=O)N1CCCC(Nc2cccc(N)c2)C1 -US08017637B2,1,COc1ccc(CNCCCNC2=CC(=O)c3sc(C)nc3C2=O)cc1.Cc1nc2c(s1)C(=O)C=C(NCCCBr)C2=O>>COc1ccc(CN(CCCNC2=CC(=O)c3sc(C)nc3C2=O)CCCNC2=CC(=O)c3sc(C)nc3C2=O)cc1 -US20090099169A1,2,Cc1cc(C(=O)Cl)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12.NN1CCOCC1>>Cc1cc(C(=O)NN2CCOCC2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 -US07112603B2,2,Cc1cc(C)c(C=C2C(=O)Nc3ccccc32)[nH]1.O=C(O)CNC(=O)OCc1ccccc1>>Cc1cc(C)c(/C=C2\C(=O)N(C(=O)CNC(=O)OCc3ccccc3)c3ccccc32)[nH]1 -US20050176689A1,7,CCOC(=O)C1=CCC(C)(C)c2cc(O[Si](C)(C)C(C)(C)C)c(C)cc21>>CCOC(=O)C1CCC(C)(C)c2cc(O[Si](C)(C)C(C)(C)C)c(C)cc21 -US20140363454A1,1,CC(C)(C)OC(=O)NCCCCCC=O.O=C(O)[C@H]1CCCCN1>>CC(C)(C)OC(=O)NCCCCCCN1CCCC[C@@H]1C(=O)O -US08541397B2,6,Cc1ccc(CC(C#Cc2ccc(CNCCC(=O)OC(C)(C)C)cc2)c2cccc(Cl)c2)cc1C>>Cc1ccc(CC(C#Cc2ccc(CNCCC(=O)O)cc2)c2cccc(Cl)c2)cc1C -US20090163520A1,1,CC(C)(C)OC(=O)NN.Ic1ccc(-n2cccn2)cc1>>CC(C)(C)OC(=O)N(N)c1ccc(-n2cccn2)cc1 -US06313310B1,3,C#CC(O)c1ccccc1.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CC(O)c3ccccc3)c21 -US05371086,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NNc1ccc([N+](=O)[O-])cn1>>CC(C)(C)OC(=O)NNc1ccc([N+](=O)[O-])cn1 -US20080280892A1,7,CCCCOC(=O)/C=C/c1cc(CO[Si](C)(C)C(C)(C)C)cc(OC)n1>>CCCCOC(=O)CCc1cc(CO[Si](C)(C)C(C)(C)C)cc(OC)n1 -US20100069629A1,2,CN1CCNCC1.COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3cccc(C(=O)O)c3)cn2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3cccc(C(=O)N4CCN(C)CC4)c3)cn2)cc1 -US06156903,6,CC(C)(C)Nc1nc(NCc2ccccc2)c(C#N)cc1F>>CC(C)(C)Nc1nc(N)c(C#N)cc1F -US20090012081A1,1,COC(=O)C(Br)c1ccccc1.Cc1c(C)c2c(c(C)c1O)C(c1ccc(C(C)C)cc1)C(C)(C)O2>>COC(=O)C(Oc1c(C)c(C)c2c(c1C)C(c1ccc(C(C)C)cc1)C(C)(C)O2)c1ccccc1 -US06407116B1,2,CCOC(=O)CNC.O=C(O)Cn1c(=O)c2ccccc2n(CCCCN2CCC(OC(c3ccccc3)c3ccccc3)CC2)c1=O>>CCOC(=O)CN(C)C(=O)Cn1c(=O)c2ccccc2n(CCCCN2CCC(OC(c3ccccc3)c3ccccc3)CC2)c1=O -US20100041647A1,7,CC(C)(C)OC(=O)N[C@@H](Cc1cccc([N+](=O)[O-])c1)C(=O)O>>CC(C)(C)OC(=O)N[C@H](CO)Cc1cccc([N+](=O)[O-])c1 -US20120232056A1,6,CCN1CCC(N(C)c2nc3cc(C(=O)OC)ccc3nc2-c2ccc(F)cc2)CC1>>CCN1CCC(N(C)c2nc3cc(C(=O)O)ccc3nc2-c2ccc(F)cc2)CC1 -US20080305169A1,8,O=C(OO)c1cccc(Cl)c1.O=C(c1cc(Cl)c(OCc2ccccc2)c(Cl)c1)N1CCSc2ccccc21>>O=C(c1cc(Cl)c(OCc2ccccc2)c(Cl)c1)N1CCS(=O)c2ccccc21 -US08088936B2,3,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(OCC)c2)c1CCC(=O)OCC.CS(=O)(=O)c1ccc(B(O)O)cc1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(OCC)cc(-c3ccc(S(C)(=O)=O)cc3)c2)c1CCC(=O)OCC -US20120122780A1,4,COC(=O)CSC(Br)C(=O)c1ccc(C)cc1Cl.NC=S>>COC(=O)CSc1scnc1-c1ccc(C)cc1Cl -US20150182509A1,1,CN1CCc2[nH]c3ccc(Cl)cc3c2C1.COc1ccc(CCBr)cc1>>COc1ccc(CCn2c3c(c4cc(Cl)ccc42)CN(C)CC3)cc1 -US20110092461A1,1,C=C(C)C.COC(=O)c1ccc(C(=O)O)c(Cl)c1>>COC(=O)c1ccc(C(=O)OC(C)(C)C)c(Cl)c1 -US20130267482A1,6,CCOC(OCC)[C@H](C)N(Cc1cccc2ccccc12)C(=O)[C@H](C)NC(=O)OCC1c2ccccc2-c2ccccc21>>CCOC(OCC)[C@H](C)N(Cc1cccc2ccccc12)C(=O)[C@H](C)N -US20100019229A1,1,CCCC[Sn](Cl)(CCCC)CCCC.CCOP(=O)(OCC)c1ccsc1>>CCCC[Sn](CCCC)(CCCC)c1sccc1P(=O)(OCC)OCC -US20070254869A1,3,CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2cc(Br)ccc21.OB(O)c1ccccc1>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2cc(-c3ccccc3)ccc21 -US04500709,6,CCOC(=O)C(=NOC)C1=CSCCO1>>CON=C(C(=O)O)C1=CSCCO1 -US20060173050A1,3,CC(=O)Nc1cc(N)c(C#N)c(Br)n1.CCC[Zn+]>>CCCc1nc(NC(C)=O)cc(N)c1C#N -US20090186391A1,7,CCOC(=O)C(NC(=O)OC(C)(C)C)C(=O)C1CCCCC1>>CCOC(=O)C(NC(=O)OC(C)(C)C)C(O)C1CCCCC1 -US20040209921A1,1,CC(=O)NCc1ccc(CNC2CCCc3cccnc32)c(CO)c1.Cc1cc(Cl)cnc1C=O>>CC(=O)NCc1ccc(CN(Cc2ncc(Cl)cc2C)C2CCCc3cccnc32)c(CO)c1 -US09079866B2,3,COc1c(Br)ccc(-c2cnc(N)cn2)c1F.OB(O)c1ccc(C(F)(F)F)cc1>>COc1c(-c2ccc(C(F)(F)F)cc2)ccc(-c2cnc(N)cn2)c1F -US20100063081A1,1,CC(C)(C)OC(=O)N1CCC(CCC=O)CC1.CSc1ccc(N)cc1F>>CSc1ccc(NCCCC2CCN(C(=O)OC(C)(C)C)CC2)cc1F -US07314883B2,2,C1CCN(C2CCNCC2)CC1.O=C(O)[C@@H](Cc1ccc2[nH]c(C(F)(F)F)nc2c1)NC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1>>O=C(N[C@H](Cc1ccc2[nH]c(C(F)(F)F)nc2c1)C(=O)N1CCC(N2CCCCC2)CC1)N1CCC(N2Cc3ccccc3NC2=O)CC1 -US08236950B2,2,Nc1ccc(Br)cc1.O=[N+]([O-])c1cc(S(=O)(=O)Cl)ccc1Cl>>O=[N+]([O-])c1cc(S(=O)(=O)Nc2ccc(Br)cc2)ccc1Cl -US04532246,1,ClCc1cccs1.NCCCNc1ccccn1>>NCCCN(Cc1cccs1)c1ccccn1 -US06713474B2,1,CN1CC2CC(O)CC2C1.Clc1ncnc2[nH]cc(I)c12>>CN1CC2CC(n3cc(I)c4c(Cl)ncnc43)CC2C1 -US20030004172A1,6,COC(=O)c1cc2c(s1)c(=O)n(Cc1ccccc1)c(=O)n2C>>COC(=O)c1cc2c(s1)c(=O)[nH]c(=O)n2C -US20150191483A1,1,NC(=O)CBr.O=S(=O)(c1ccc(F)cc1)[C@@]1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCNC1>>NC(=O)CN1CC[C@](c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1 -US20130012518A1,2,CNc1ncc2c(n1)CCN(c1cc(N)ccc1C)C2.O=C=Nc1cccc(C(F)(F)F)c1>>CNc1ncc2c(n1)CCN(c1cc(NC(=O)Nc3cccc(C(F)(F)F)c3)ccc1C)C2 -US20050080124A1,2,COc1ccc(N)cc1-c1c(Cl)cnn1C.O=C=Nc1cccc([N+](=O)[O-])c1>>COc1ccc(NC(=O)Nc2cccc([N+](=O)[O-])c2)cc1-c1c(Cl)cnn1C -US07094789B2,9,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Oc2cccc3cncc(Br)c23)CC1.N>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Oc2cccc3cncc(N)c23)CC1 -US20150031668A1,3,N#Cc1ccc(B(O)O)cc1.N[C@]1(c2ccc(Br)cc2)CCOc2cccnc21>>N#Cc1ccc(-c2ccc([C@@]3(N)CCOc4cccnc43)cc2)cc1 -US08518972B2,1,COC(=O)CCC(C(N)=O)N1Cc2c(O)cccc2C1=O.OCC1COc2ccccc2C1>>COC(=O)CCC(C(N)=O)N1Cc2c(OCC3COc4ccccc4C3)cccc2C1=O -US08026255B2,2,CCOc1cc(CN2CCC(Nc3ccc(C(=O)O)cn3)CC2)cc(OCC)c1Cl.NCCO>>CCOc1cc(CN2CCC(Nc3ccc(C(=O)NCCO)cn3)CC2)cc(OCC)c1Cl -US07863291B2,9,COCc1cc(Cl)ncn1.[NH4+]>>COCc1cc(N)ncn1 -US07943774B2,2,O=C(O)Cc1cc(C(F)(F)F)ccc1Cl.c1ccc(CCc2csc(C3CCNCC3)n2)cc1>>O=C(Cc1cc(C(F)(F)F)ccc1Cl)N1CCC(c2nc(CCc3ccccc3)cs2)CC1 -US20140163012A1,6,CC(C)(C)OC(=O)N1CCc2oc3cc(-n4ccc(OCc5ccc(Cl)cn5)cc4=O)ccc3c2C1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc2c3c(oc2c1)CCNC3 -US07998988B2,1,CC(C)(C)c1ccc(CBr)cc1.CCOC(=O)CCCCC(/C=C/c1ccccc1O)Cc1ccc(C#N)cc1>>CCOC(=O)CCCCC(/C=C/c1ccccc1OCc1ccc(C(C)(C)C)cc1)Cc1ccc(C#N)cc1 -US08841455B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)[C@@H]1NCC[C@@H]1O>>CC(C)(C)OC(=O)N1CC[C@H](O)[C@@H]1C(=O)O -US04266005,4,CCCCCCCCCCCCN.O=C1C=CC(=O)O1>>CCCCCCCCCCCCN1C(=O)C=CC1=O -US20140187545A1,6,CCOC(=O)C(C#N)Cc1cccc(Cl)c1Cl>>N#CC(Cc1cccc(Cl)c1Cl)C(=O)O -US08163906B2,3,COC(=O)C(=O)N(c1ccccc1)c1cc(Cl)ccc1C(=O)CCc1ccc(S(=O)(=O)NCC(O)CO)cc1>>COC(=O)c1c(Cc2ccc(S(=O)(=O)NCC(O)CO)cc2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 -US20150158851A1,3,CC1(C)OB(C2=CCC3(CC2)OCCO3)OC1(C)C.C[Si](C)(C)CCOCn1cc(I)cn1>>C[Si](C)(C)CCOCn1cc(C2=CCC3(CC2)OCCO3)cn1 -US04024271,6,O=C1c2ccccc2C(=O)N1CCCSc1ncco1>>NCCCSc1ncco1 -US20120309796A1,6,Cc1cncc(-c2ccc(S(=O)(=O)NC3CCCCc4c(OCC(=O)OC(C)(C)C)cccc43)cc2)c1>>Cc1cncc(-c2ccc(S(=O)(=O)NC3CCCCc4c(OCC(=O)O)cccc43)cc2)c1 -US20100311966A1,8,CCc1[nH]c(C(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2O)nc1Cl>>CCc1[nH]c(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2=O)nc1Cl -US07186734B2,1,CCCCBr.COc1ccc(-c2c[nH]c(-c3ccccc3)n2)cc1>>CCCCn1cc(-c2ccc(OC)cc2)nc1-c1ccccc1 -US05859007,6,COc1ccc(N(C(=O)CN2C(=O)C(Cc3nn(Cc4ccccc4)c4ccccc34)C(=O)N(c3ccccc3)c3ccccc32)C(C)C)cc1>>COc1ccc(N(C(=O)CN2C(=O)C(Cc3n[nH]c4ccccc34)C(=O)N(c3ccccc3)c3ccccc32)C(C)C)cc1 -US20100216746A1,9,N.N#Cc1cc(Cl)cc(Oc2c(F)ccc(CBr)c2Cl)c1>>N#Cc1cc(Cl)cc(Oc2c(F)ccc(CN)c2Cl)c1 -US05186717,1,Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1.NCCO>>Cc1cc([N+](=O)[O-])c(NCCO)c([N+](=O)[O-])c1 -US08440666B2,8,C[C@H]1[C@H](Nc2cnn(CC(=O)NCc3ccncc3)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C.O=C(OO)c1cccc(Cl)c1>>C[C@H]1[C@H](Nc2cnn(CC(=O)NCc3cc[n+]([O-])cc3)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C -US20110130398A1,2,CCCCOc1cc(C(=O)O)ccc1[N+](=O)[O-].CO>>CCCCOc1cc(C(=O)OC)ccc1[N+](=O)[O-] -US05180730,1,CCCc1c(CCl)ccc(C(C)=O)c1O.Nc1nnc(S)s1>>CCCc1c(CSc2nnc(N)s2)ccc(C(C)=O)c1O -US20070105864A1,1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.O=[N+]([O-])c1cccc(F)c1>>CC(C)(C)OC(=O)N1CCC(Oc2cccc([N+](=O)[O-])c2)C1 -US06566526B2,6,CC(=O)OC(c1ccc(C(=O)CCCCl)cc1)C(C)C>>CC(C)C(O)c1ccc(C(=O)CCCCl)cc1 -US20100331385A1,7,CC(C)(C)c1cc(NC(=O)NCc2cc(F)ccc2Oc2ccc3c(cnn3CCO)c2)n(-c2ccc(C=O)cc2)n1>>CC(C)(C)c1cc(NC(=O)NCc2cc(F)ccc2Oc2ccc3c(cnn3CCO)c2)n(-c2ccc(CO)cc2)n1 -US20080188651A1,6,C=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/C=C\C(=O)OC)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C>>C=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/C=C\C(=O)O)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C -US05679683,2,CC(=O)O.Nc1cc2nc[nH]c(=O)c2cc1[N+](=O)[O-]>>CC(=O)Nc1cc2nc[nH]c(=O)c2cc1[N+](=O)[O-] -US04778822,7,Cc1c(F)ccc([N+](=O)[O-])c1Cl>>Cc1c(F)ccc(N)c1Cl -US06921763B2,1,CC(C)(C)OC(=O)CBr.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCNCC1>>CC(C)(C)OC(=O)CN1CCC(n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)CC1 -US20150045343A1,3,N#CCC(=O)N1CCCC1.Nc1ncnc2c1c(-c1ccc(Cl)cc1)cn2-c1cccc(C=O)c1>>N#C/C(=C\c1cccc(-n2cc(-c3ccc(Cl)cc3)c3c(N)ncnc32)c1)C(=O)N1CCCC1 -US20100004221A1,2,NN.O=C(O)c1ccc(Br)cc1F>>NNC(=O)c1ccc(Br)cc1F -US05543547,3,O=C(Oc1ccccc1)Oc1ccccc1>>O=C(Oc1ccccc1)c1ccccc1O -US07442698B2,1,CN(C)CCOc1ccc(N)cc1.COc1ccc(OC)c(CN(C(=O)Oc2c(C)cccc2C)c2ccnc(Cl)n2)c1>>COc1ccc(OC)c(CN(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(OCCN(C)C)cc3)n2)c1 -US20110306602A1,2,CCCS(=O)(=O)Cl.Cc1ccc([N+](=O)[O-])cc1N>>CCCS(=O)(=O)Nc1cc([N+](=O)[O-])ccc1C -US20090062348A1,1,N.O=Cc1cc2ccc(OCC3CC3)cc2[nH]1>>NCc1cc2ccc(OCC3CC3)cc2[nH]1 -US20130231335A1,3,CCCC[Sn](CCCC)(CCCC)c1cscn1.CC[C@@H]1C(=O)N(C)c2cnc(-n3cnc(Br)c3)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(-n3cnc(-c4cscn4)c3)nc2N1C1CCCC1 -US20030092712A1,2,COC(=O)c1cc(Br)c(/C=C\C(=O)O)c(Br)c1.Nc1c(Cl)cccc1Cl>>COC(=O)c1cc(Br)c(/C=C\C(=O)Nc2c(Cl)cccc2Cl)c(Br)c1 -US20100063098A1,2,Cc1ccc(N)cc1[N+](=O)[O-].O=C(O)C1CC1>>Cc1ccc(NC(=O)C2CC2)cc1[N+](=O)[O-] -US07985876B2,3,COC(=O)c1ccc(CCC(C=O)CCc2ccc(C(=O)OC)cc2)cc1.Oc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)c1ccc(CCC(/C=C/c2ccccc2O)CCc2ccc(C(=O)OC)cc2)cc1 -US08748432B2,2,Cc1cc(C(F)(F)F)nn1CC(=O)N1CCN(c2cccc(N)c2)CC1.O=C(O)c1cccc(Cl)c1O>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCN(c2cccc(NC(=O)c3cccc(Cl)c3O)c2)CC1 -US04005208,6,CN(C)C(=O)N1CCCC(N2C(=O)c3ccccc3C2=O)C1>>CN(C)C(=O)N1CCCC(N)C1 -US06610707B1,8,O=S(=O)(c1nc2ccccc2[nH]1)N1CCCCC1c1noc(COc2ccc(CO)cc2)n1>>O=Cc1ccc(OCc2nc(C3CCCCN3S(=O)(=O)c3nc4ccccc4[nH]3)no2)cc1 -US20110071194A1,1,COc1ccc(F)c(C=O)c1.NNc1ccc(F)cc1>>COc1ccc(F)c(C=NNc2ccc(F)cc2)c1 -US20030203898A1,6,CCOC(=O)C(=O)Nc1cc(C)c(Cc2ccc(OC)c(Cc3ccc(F)cc3)c2)c(C)c1>>COc1ccc(Cc2c(C)cc(NC(=O)C(=O)O)cc2C)cc1Cc1ccc(F)cc1 -US20130274266A1,2,CCOC(=O)c1nccn1C[C@](C)(N)c1cccc(Br)c1>>C[C@@]1(c2cccc(Br)c2)Cn2ccnc2C(=O)N1 -US07098212B2,2,CC(=O)OC(C)(C)C(=O)Cl.C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1CS(N)(=O)=O>>CC(=O)OC(C)(C)C(=O)NS(=O)(=O)Cc1cc(Cl)ccc1OCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C -US20060287356A1,6,N#Cc1c(O)c2c(-c3cc(Br)c(OCc4ccccc4)c(Br)c3)csc2[nH]c1=O>>N#Cc1c(O)c2c(-c3cc(Br)c(O)c(Br)c3)csc2[nH]c1=O -US05527791,2,CC(=O)S[C@H]1C[C@@H](C(=O)Nc2cccc(C(=O)O)c2)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1.NCC(=O)OCc1ccc([N+](=O)[O-])cc1>>CC(=O)S[C@H]1C[C@@H](C(=O)Nc2cccc(C(=O)NCC(=O)OCc3ccc([N+](=O)[O-])cc3)c2)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1 -US07202363B2,6,CCN(CC)C/C=C/c1cnc(N)c2c(-c3ccc(NC(=O)OC(C)(C)C)c(OC)c3)csc12>>CCN(CC)C/C=C/c1cnc(N)c2c(-c3ccc(N)c(OC)c3)csc12 -US07737166B2,6,COc1cccc(-c2c(C)c(C#N)c3nc(C(C)(C)C)oc3c2N2CC[C@H](N(C)C)C2)c1>>Cc1c(-c2cccc(O)c2)c(N2CC[C@H](N(C)C)C2)c2oc(C(C)(C)C)nc2c1C#N -US20090264445A1,2,CC(C)(O)Cn1ccc(N)n1.COC1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)O)C1>>COC1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)Nc2ccn(CC(C)(C)O)n2)C1 -US20130109710A1,3,CC(=O)Oc1cc(C=O)ccc1OCC1=CC2(CCCC2)CCC1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1ccc(OCC2=CC3(CCCC3)CCC2)c(OC(C)=O)c1 -US07816522B2,1,CC(C)(C)[Si](C)(C)OCCBr.COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)c(O)cc1F>>COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)c(OCCO[Si](C)(C)C(C)(C)C)cc1F -US08969346B2,6,CC(=O)Nc1nc(-c2ccc(NCC(C)(C)c3ccc(F)cc3)nn2)c[nH]1>>CC(C)(CNc1ccc(-c2c[nH]c(N)n2)nn1)c1ccc(F)cc1 -US05736534,1,COc1ccc2c(Cl)ncnc2c1.Cc1cccc2c1NCC2>>COc1ccc2c(N3CCc4cccc(C)c43)ncnc2c1 -US20100041891A1,2,NCC(N)=O.O=C(O)c1cc(-c2ccc(F)c3cc(Cc4cc(F)cc(Cl)c4)sc23)ccc1F>>NC(=O)CNC(=O)c1cc(-c2ccc(F)c3cc(Cc4cc(F)cc(Cl)c4)sc23)ccc1F -US20100093757A1,7,CCOC(=O)[C@H](C)O[Si](C)(C)C(C)(C)C>>C[C@@H](CO)O[Si](C)(C)C(C)(C)C -US20060287377A1,7,O=C(Cn1cnc2cccc([N+](=O)[O-])c21)Nc1cccc(C(F)(F)F)c1>>Nc1cccc2ncn(CC(=O)Nc3cccc(C(F)(F)F)c3)c12 -US04915491,2,C=C(C)C(=O)Cl.O=[N+]([O-])c1ccc(C=Cc2ccc(OCCCCCCO)cc2)cc1>>C=C(C)C(=O)OCCCCCCOc1ccc(C=Cc2ccc([N+](=O)[O-])cc2)cc1 -US06890947B2,1,C[Si](C)(C)CCOCCl.O=Cc1ccc2[nH]ccc2c1>>C[Si](C)(C)CCOCn1ccc2cc(C=O)ccc21 -US20110237573A1,3,CC(C)(C)OC(=O)Cc1cnc(Cl)c(F)c1.OB(O)c1ccnc(F)c1>>CC(C)(C)OC(=O)Cc1cnc(-c2ccnc(F)c2)c(F)c1 -US06177474B1,3,CC(C)C(=O)Cl.Oc1cc(O)cc(O)c1>>CC(C)C(=O)c1c(O)cc(O)cc1O -US04013777,1,ClCC1CO1.Oc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>c1ccc(COc2ccc(OCC3CO3)cc2OCc2ccccc2)cc1 -US20060142575A1,3,C#CCCc1ccccc1.N#Cc1ncc(Br)c(NC2CCCC2)n1>>N#Cc1ncc(C#CCCc2ccccc2)c(NC2CCCC2)n1 -US20150209358A1,2,CC(C)n1cc(C(=O)O)c(=O)n(-c2ccc(F)cc2)c1=O.COc1cc2nccc(Oc3ccc(N)cc3C(C)C)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3C(C)C)c2cc1OC -US04131677,7,O=[N+]([O-])c1ccc2nc(-c3ccccc3)oc2n1>>Nc1ccc2nc(-c3ccccc3)oc2n1 -US06353006B1,1,CCC(CC)CBr.Cc1cc([N+](=O)[O-])ccc1N=C1NC2(CCCC2)CS1>>CCC(CC)CN1C(=Nc2ccc([N+](=O)[O-])cc2C)SCC12CCCC2 -US04138581,7,COc1ccc(C(=O)Oc2ccc(C(=O)CNC(C)(C)C)cc2OC(=O)c2ccc(OC)cc2)cc1>>COc1ccc(C(=O)Oc2ccc(C(O)CNC(C)(C)C)cc2OC(=O)c2ccc(OC)cc2)cc1 -US08178522B2,6,COC(=O)c1cnc(CCc2c(-c3ccccn3)noc2C)s1>>Cc1onc(-c2ccccn2)c1CCc1ncc(C(=O)O)s1 -US07122571B2,1,CC(=O)c1cccs1.NNc1ccc(S(N)(=O)=O)cc1>>CC(=NNc1ccc(S(N)(=O)=O)cc1)c1cccs1 -US04011220,9,Nc1cn[n+](C2CCCCC2)c(Cl)c1>>Nc1cc[n+](C2CCCCC2)nc1 -US05833885,1,CNN.FC(F)(F)c1cc(Cl)nc(C(F)(F)F)c1>>CN(N)c1cc(C(F)(F)F)cc(C(F)(F)F)n1 -US08268754B2,3,C=C(Br)C(F)(F)F.OB(O)c1cc(Cl)cc(Cl)c1>>C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F -US20150252038A1,6,COCC1(c2ccc(F)cc2)CCN(Cc2cc(F)c(C(=O)OC(C)(C)C)cc2C2CC2)CC1>>COCC1(c2ccc(F)cc2)CCN(Cc2cc(F)c(C(=O)O)cc2C2CC2)CC1 -US20050288287A1,2,CCOc1cc(C(C)(C)C#N)c(Cl)cc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.Cc1noc(C)c1C(=O)N1CCNCC1>>CCOc1cc(C(C)(C)C#N)c(Cl)cc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(C(=O)c2c(C)noc2C)CC1 -US08389550B2,6,COC(=O)c1ccc(/C=C/c2c(-c3ccccc3)noc2C)nc1>>Cc1onc(-c2ccccc2)c1/C=C/c1ccc(C(=O)O)cn1 -US20040204584A1,2,COc1ccc(C2COCCO2)c2sc(N)nc12.O=C(O)Cc1ccccn1>>COc1ccc(C2COCCO2)c2sc(NC(=O)Cc3ccccn3)nc12 -US20110009396A1,1,CC1=C2[C@H](O)C(O)(C(CO)CN3CCN(Cc4ccccc4)CC3)CC[C@@]2(C)CCC1>>CC1=C2[C@@H]3OCC(CN4CCN(Cc5ccccc5)CC4)C3(O)CC[C@@]2(C)CCC1 -US06281206B1,1,CC(C)(C)OC(=O)N1CCC(CO)CC1.Cc1cc(O)cc(OS(=O)(=O)c2cccc(Cl)c2)c1>>Cc1cc(OCC2CCN(C(=O)OC(C)(C)C)CC2)cc(OS(=O)(=O)c2cccc(Cl)c2)c1 -US20130252944A1,1,COc1ccc(Cn2cc3c(n2)CC(C)Cc2sc(N)nc2-3)cc1.Cc1ccnc(Cl)n1>>COc1ccc(Cn2cc3c(n2)CC(C)Cc2sc(Nc4nccc(C)n4)nc2-3)cc1 -US04668831,1,CC(C)(C)c1cc(O)ccc1Br.S=C(Cl)Cl>>CC(C)(C)c1cc(OC(=S)Cl)ccc1Br -US05599813,6,CCCC1=C(C(=O)Nc2ccc(SCCCCCC(=O)OCC)cc2)SC2=NCCCN21>>CCCC1=C(C(=O)Nc2ccc(SCCCCCC(=O)O)cc2)SC2=NCCCN21 -US20140213570A1,1,COc1ccc(CN)cc1.C[C@@H](C=O)O[Si](C)(C)C(C)(C)C>>COc1ccc(C/N=C/[C@H](C)O[Si](C)(C)C(C)(C)C)cc1 -US20150259366A1,6,COC(=O)c1cc(N(Cc2ccc(Cl)cc2)C(=O)c2ccc(Oc3ccccc3)cc2)ccc1O>>O=C(O)c1cc(N(Cc2ccc(Cl)cc2)C(=O)c2ccc(Oc3ccccc3)cc2)ccc1O -US20150099786A1,8,O=C(NCc1ccccn1)C(O)C(Cc1ccccc1)NC(=O)[C@H]1CCC(=O)N1Cc1ccccc1>>O=C(NCc1ccccn1)C(=O)C(Cc1ccccc1)NC(=O)[C@H]1CCC(=O)N1Cc1ccccc1 -US20090131468A1,3,C#CC1CCCC1.NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)c(CO)c1>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(C#CC2CCCC2)c(CO)c1 -US06218376B1,1,CN.Cn1cc(C2c3ccc(Cl)cc3C=Cc3sc(Cl)nc32)c(=O)[nH]c1=O>>CNc1nc2c(s1)C=Cc1cc(Cl)ccc1C2c1cn(C)c(=O)[nH]c1=O -US20140371202A1,6,CC(C)(C)OC(=O)Nc1ccc2[nH]nc(I)c2c1>>Nc1ccc2[nH]nc(I)c2c1 -US06720427B2,2,Nc1ncc(C2CCC2)s1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ncc(C2CCC2)s1)Oc1ccccc1 -US20080200491A1,6,CC(C)(C)c1ccc2c(c1)C1(CCN(C(=O)OCc3ccccc3)CC1)CN2C(=O)c1c(F)cccc1F>>CC(C)(C)c1ccc2c(c1)C1(CCNCC1)CN2C(=O)c1c(F)cccc1F -US20050130992A1,7,O=[N+]([O-])C1NC=CN1c1ccncc1>>NC1NC=CN1c1ccncc1 -US20030139425A1,2,C[C@H]1CN(Cc2ccc(F)cc2)[C@@H](CO)CN1.O=C(Cl)COc1ccc(Cl)cc1>>C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](CO)CN1C(=O)COc1ccc(Cl)cc1 -US08470843B2,7,O=C1CN(S(=O)(=O)c2ccccc2Cl)CCC12CCN(c1ccc(OC(F)(F)F)cc1)C2=O>>O=C1N(c2ccc(OC(F)(F)F)cc2)CCC12CCN(S(=O)(=O)c1ccccc1Cl)CC2O -US20100069381A1,4,CSc1ccc(Nc2cc(C(=O)NNC(=O)C(C)(C)OC(C)=O)ccn2)cc1>>CSc1ccc(Nc2cc(-c3nnc(C(C)(C)OC(C)=O)o3)ccn2)cc1 -US07119120B2,6,COC(=O)c1cc(Br)ccc1NS(=O)(=O)c1ccc(OC(F)(F)F)cc1>>O=C(O)c1cc(Br)ccc1NS(=O)(=O)c1ccc(OC(F)(F)F)cc1 -US04478837,1,C=CCOC(=O)N1CCc2nnc(NN)cc2C1.CC(C)=O>>C=CCOC(=O)N1CCc2nnc(NN=C(C)C)cc2C1 -US20130274244A1,1,CC(C)(C)OC(N)=O.Fc1ccnc(Cl)c1>>CC(C)(C)OC(=O)Nc1cc(F)ccn1 -US05290785,3,Cc1c2n(c3ccccc13)C(=O)CCC2.Cc1ncccc1C=O>>Cc1ncccc1C(O)C1CCc2c(C)c3ccccc3n2C1=O -US20140296136A1,6,COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1Cc3ccccc3C1)NC(=O)O[C@@H]1C[C@H]1CCCCCc1c(nc3ccccc3c1OCCCN(C)C)O2>>CN(C)CCCOc1c2c(nc3ccccc13)O[C@@H]1C[C@@H](C(=O)O)N(C1)C(=O)[C@H](C1Cc3ccccc3C1)NC(=O)O[C@@H]1C[C@H]1CCCCC2 -US20120142771A1,6,CCOC(=O)C(C)c1ccccc1-c1ccccc1>>CC(C(=O)O)c1ccccc1-c1ccccc1 -US20120178732A1,1,CCOC(=O)CBr.Oc1ccc(F)cc1Br>>CCOC(=O)COc1ccc(F)cc1Br -US20110184177A1,2,COC(=O)C(C)(C)N.COc1ccc(COc2c(C(=O)O)ccc3ccccc23)cn1>>COC(=O)C(C)(C)NC(=O)c1ccc2ccccc2c1OCc1ccc(OC)nc1 -US09072731B2,1,CCOC(=O)c1sc(-c2ccc(Cl)cc2)c(CBr)c1-c1ccc(S(=O)(=O)N=CN(C)C)cc1.CNC>>CCOC(=O)c1sc(-c2ccc(Cl)cc2)c(CN(C)C)c1-c1ccc(S(=O)(=O)N=CN(C)C)cc1 -US20140323530A1,7,CN(C)C(=O)CCC#Cc1cccc(C(O)CCNC(=O)C(F)(F)F)c1>>CN(C)C(=O)CCCCc1cccc(C(O)CCNC(=O)C(F)(F)F)c1 -US20050256175A1,4,NC(=S)Nc1ccc(C(F)(F)F)cc1.O=C(CBr)c1ccc(Cl)cc1>>FC(F)(F)c1ccc(Nc2nc(-c3ccc(Cl)cc3)cs2)cc1 -US20050154042A1,2,CCOC(=O)c1c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)cn1C(C)C.Cc1ccnc(N)n1>>Cc1ccnc(NC(=O)c2c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)cn2C(C)C)n1 -US04439448,7,CCOC(=O)C(C)(C)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)C(C)(C)c1ccc(N)cc1 -US07989477B2,7,Nc1nccc(Oc2ccc([N+](=O)[O-])cc2F)c1C#Cc1ccccn1>>Nc1ccc(Oc2ccnc(N)c2C#Cc2ccccn2)c(F)c1 -US08163956B2,7,Cn1c(SCC2CC2)nnc1C(=O)CC1CC1>>Cn1c(SCC2CC2)nnc1C(O)CC1CC1 -US08309734B2,2,O=C(O)c1cccnc1Oc1cc(Cl)ccc1Cl.c1ccc2c(c1)NCCO2>>O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CCOc2ccccc21 -US20050282858A1,2,O=C(O)C1(c2ccc(-c3ccccc3)nc2)CC1.O=C1O[C@]2(CCNC2)c2ccccc21>>O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-c5ccccc5)nc4)CC3)C2)c2ccccc21 -US20140288069A1,1,COc1nccc2oc(-c3cnc4ccc(Cl)nn34)cc12.NCC(O)C1CCOCC1>>COc1nccc2oc(-c3cnc4ccc(NCC(O)C5CCOCC5)nn34)cc12 -US06534546B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccc(N)cc1F>>CC(C)(C)OC(=O)NCCc1ccc(N)cc1F -US20090264384A1,1,OB(O)CCCCCBr.c1ccc2[nH]c(-c3cscn3)nc2c1>>OB(O)CCCCCn1c(-c2cscn2)nc2ccccc21 -US20050282824A1,1,C1CCNCC1.COC(=O)c1cc(Cl)nc(Cl)n1>>COC(=O)c1cc(N2CCCCC2)nc(Cl)n1 -US20120309789A1,1,CCCO[C@@H]1CC[C@@H](N2CCC(N)CC2)CC1.Cc1cc(F)c([N+](=O)[O-])cc1Cl>>CCCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)c(Cl)cc3[N+](=O)[O-])CC2)CC1 -US05380915,3,COC(=O)c1ccc(C=O)cc1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>COC=Cc1ccc(C(=O)OC)cc1 -US20100093757A1,2,COC(=O)CO.Cc1csc(N)n1>>Cc1csc(NC(=O)CO)n1 -US05175301,6,O=C1c2ccccc2C(=O)N1Cc1ccc(Br)nc1>>NCc1ccc(Br)nc1 -US05583134,7,COCC(=O)NCC(CCOC1CCCCO1)c1ccc(Cl)c(Cl)c1>>COCCNCC(CCOC1CCCCO1)c1ccc(Cl)c(Cl)c1 -US20150274688A1,1,CCCCN(CCCC)CCCOc1ccc(C(=O)Cl)cc1.CNOC>>CCCCN(CCCC)CCCOc1ccc(C(=O)N(C)OC)cc1 -US20130150339A1,1,CN.COc1cc(C(F)(F)F)ccc1-c1nc(Cl)cc2cc(S(=O)(=O)Nc3nccs3)ccc12>>CNc1cc2cc(S(=O)(=O)Nc3nccs3)ccc2c(-c2ccc(C(F)(F)F)cc2OC)n1 -US07622605B2,7,CC(=O)c1cncc(Br)c1>>CCc1cncc(Br)c1 -US20050137398A1,1,Ic1ccc(Oc2ccccc2)cc1.OC1CN2CCC1CC2>>c1ccc(Oc2ccc(OC3CN4CCC3CC4)cc2)cc1 -US20040209886A1,2,Cc1c(N)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12.O=C(O)c1ccccc1F>>Cc1c(NC(=O)c2ccccc2F)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12 -US04851425,6,COC(=O)CCCCCc1nn(-c2ccc(F)cc2)c2c1CCC2>>O=C(O)CCCCCc1nn(-c2ccc(F)cc2)c2c1CCC2 -US05962473,2,CN1CCC(c2c[nH]c3ccc(N)cc23)CC1.O=C(O)C1CCCCC1>>CN1CCC(c2c[nH]c3ccc(NC(=O)C4CCCCC4)cc23)CC1 -US20100216788A1,2,CC(C)(C)N.O=C(O)c1cc(Oc2ccc(Nc3ncnc4ccn(CCOCCO)c34)cc2Cl)cc(C(F)(F)F)c1>>CC(C)(C)NC(=O)c1cc(Oc2ccc(Nc3ncnc4ccn(CCOCCO)c34)cc2Cl)cc(C(F)(F)F)c1 -US20060211678A1,6,CC(C)(C)OC(=O)N1CC=C(c2cc3c(Nc4ccc5[nH]nc(Cl)c5c4)ncnc3[nH]2)CC1>>Clc1n[nH]c2ccc(Nc3ncnc4[nH]c(C5=CCNCC5)cc34)cc12 -US08088925B2,2,CC(C)N1CCC(N)CC1.O=C(N[C@@H](COCc1ccccc1)CS(=O)(=O)Cl)OCc1ccccc1>>CC(C)N1CCC(NS(=O)(=O)C[C@H](COCc2ccccc2)NC(=O)OCc2ccccc2)CC1 -US20070088044A1,1,CC(C)(C)OC(=O)N1CC(O)C1.Fc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl>>CC(C)(C)OC(=O)N1CC(Oc2cccc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1 -US08445692B2,1,COc1ccccc1CBr.Cc1noc(C)c1Cn1cc(N2C(=O)NC(C)(C)C2=O)cn1>>COc1ccccc1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C -US20130072511A1,9,N#Cc1ncc(N)cc1C(F)(F)F.S=C(Cl)Cl>>N#Cc1ncc(N=C=S)cc1C(F)(F)F -US20090076086A1,2,Cc1cnc(SCCS(=O)(=O)c2ccccc2)c(C(=O)O)c1.NCc1cccs1>>Cc1cnc(SCCS(=O)(=O)c2ccccc2)c(C(=O)NCc2cccs2)c1 -US08815869B2,2,O=C(O)CN1CCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O.c1ccc(CN2CCC3(CC2)CNC3)cc1>>O=C(CN1CCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O)N1CC2(CCN(Cc3ccccc3)CC2)C1 -US20090069282A1,3,C#CCOc1ccc(-c2ccc(Cl)cc2)cn1.Ic1ccc(CN2CCCC2)cc1>>Clc1ccc(-c2ccc(OCC#Cc3ccc(CN4CCCC4)cc3)nc2)cc1 -US20150065550A1,1,BrCc1ccccc1.C=CCC(O)Cc1ccccc1C>>C=CCC(Cc1ccccc1C)OCc1ccccc1 -US20030153553A1,1,CS(N)(=O)=O.Cc1cc(N2CCCC2)c2ccc(I)cc2n1>>Cc1cc(N2CCCC2)c2ccc(NS(C)(=O)=O)cc2n1 -US06080773,9,CC(N=[N+]=[N-])c1ccccc1-c1noc2ccccc12>>CC(N)c1ccccc1-c1noc2ccccc12 -US07915267B2,7,COc1ccc([N+](=O)[O-])c(C(N)=O)c1>>COc1ccc(N)c(C(N)=O)c1 -US20140187553A1,3,Brc1cncc(C2CC2)n1.COc1ccc(CNc2nnc(-c3ccc4c(c3)c(B3OC(C)(C)C(C)(C)O3)cn4S(=O)(=O)c3ccc(C)cc3)o2)cc1>>COc1ccc(CNc2nnc(-c3ccc4c(c3)c(-c3cncc(C5CC5)n3)cn4S(=O)(=O)c3ccc(C)cc3)o2)cc1 -US20060111347A1,6,COC(=O)CCC1(S(=O)(=O)c2ccc3ccccc3c2)CC1>>O=C(O)CCC1(S(=O)(=O)c2ccc3ccccc3c2)CC1 -US08575208B2,6,COC(=O)[C@@H]1C[C@@]2(CC(=O)N(c3cccc(Cl)c3)C2)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C>>COC(=O)[C@@H]1C[C@@]2(CC(=O)N(c3cccc(Cl)c3)C2)CN1C(=O)[C@@H](N)C(C)(C)C -US05294632,6,O=C(CCNC(=O)[C@H](Cc1ccc(-c2ccccc2)cc1)NCP(=O)(Oc1ccccc1)Oc1ccccc1)OCc1ccccc1>>O=C(O)CCNC(=O)[C@H](Cc1ccc(-c2ccccc2)cc1)NCP(=O)(Oc1ccccc1)Oc1ccccc1 -US20090099231A1,2,CC(C)(C)OC(=O)N1CCc2nc(N3CC[C@H](N)C3=O)sc2C1.O=S(=O)(Cl)/C=C/c1ccc(Cl)s1>>CC(C)(C)OC(=O)N1CCc2nc(N3CC[C@H](NS(=O)(=O)/C=C/c4ccc(Cl)s4)C3=O)sc2C1 -US05547949,1,CC(C)(C)CN.CC(C)(C)Nc1nc(Cl)cc(Cl)n1>>CC(C)(C)CNc1cc(Cl)nc(NC(C)(C)C)n1 -US06984657B1,6,CCOC(=O)c1cc2cc(OC)ccc2[nH]1>>CCOC(=O)c1cc2cc(O)ccc2[nH]1 -US08258131B2,2,CC1(C)C=C(c2ccc(F)cc2)c2ccc(N)cc2O1.CS(=O)(=O)Cl>>CC1(C)C=C(c2ccc(F)cc2)c2ccc(NS(C)(=O)=O)cc2O1 -US05686442,3,C#CC(=O)OCC.COCOc1ccc(C=O)c([N+](=O)[O-])c1>>CCOC(=O)C#CC(O)c1ccc(OCOC)cc1[N+](=O)[O-] -US05712268,8,CC(C)(C)[Si](C)(C)N1C(=O)[C@@H]2[C@H]1[C@@H](O)CN2C(=O)OCc1ccccc1>>CC(C)(C)[Si](C)(C)N1C(=O)[C@@H]2[C@H]1C(=O)CN2C(=O)OCc1ccccc1 -US04075345,2,NCc1cccnc1.O=C=Nc1ccc(S)cc1>>O=C(NCc1cccnc1)Nc1ccc(S)cc1 -US06350878B1,6,C[C@@H](CCCOCc1ccccc1)CO[Si](C)(C)C(C)(C)C>>C[C@@H](CCCO)CO[Si](C)(C)C(C)(C)C -US04650900,2,CCC(C(=O)Cl)C(C#N)(c1ccccc1)c1ccccc1.CNC>>CCC(C(=O)N(C)C)C(C#N)(c1ccccc1)c1ccccc1 -US20100048625A1,2,C[C@@H](N)CO.Cc1cc(OCCCC2CCN(c3nc(C(C)C)no3)CC2)cnc1C(=O)O>>Cc1cc(OCCCC2CCN(c3nc(C(C)C)no3)CC2)cnc1C(=O)N[C@H](C)CO -US20120289474A1,2,COC(=O)c1sc(Br)cc1NC(=O)NC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(Br)sc3c2=O)CC1 -US20150005165A1,3,COC(=O)c1nc(Br)cc(N)c1Cl.OB(O)c1ccc2nc(-c3ccccc3)oc2c1F>>COC(=O)c1nc(-c2ccc3nc(-c4ccccc4)oc3c2F)cc(N)c1Cl -US20030176481A1,1,COc1cc(C=O)ccc1F.CS(=O)c1ccc(N)cc1>>COc1cc(C=Nc2ccc(S(C)=O)cc2)ccc1F -US20090233897A1,1,Clc1ncccc1CC(c1cccnc1)c1cccnc1.Nc1ccccc1N>>Nc1ccccc1Nc1ncccc1CC(c1cccnc1)c1cccnc1 -US05260294,3,C#CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1.Ic1cccs1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C#Cc1cccs1)O2 -US20140179668A1,2,COC(=O)[C@@H]1CCCN1c1nc2c(c(Nc3cc(C(C)C)[nH]n3)n1)CCC2.Nc1nccs1>>CC(C)c1cc(Nc2nc(N3CCC[C@H]3C(=O)Nc3nccs3)nc3c2CCC3)n[nH]1 -US07696240B2,1,CCOC(=O)c1cc2cc(C)ccc2[nH]1.Fc1ccc2cccc(CBr)c2c1>>CCOC(=O)c1cc2cc(C)ccc2n1Cc1cccc2ccc(F)cc12 -US05726127,6,COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2sccc2C(CF)OC(C)=O)n1>>COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2sccc2C(O)CF)n1 -US07491747B2,1,O=C1OCCC1Br.Oc1ccc(Br)cc1>>O=C1OCCC1Oc1ccc(Br)cc1 -US20130217664A1,1,COc1ccc(COc2ccc(N)c(C)c2)cc1.Cn1cnc2cnc(Cl)cc21>>COc1ccc(COc2ccc(Nc3cc4c(cn3)ncn4C)c(C)c2)cc1 -US20150045339A1,6,CCCNc1nc(Nc2cccc(F)c2)ncc1C#C[C@@H]1CCC[C@H](NC(=O)OC(C)(C)C)C1>>CCCNc1nc(Nc2cccc(F)c2)ncc1C#C[C@@H]1CCC[C@H](N)C1 -US06300363B1,2,Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12.O=C(O)CC(F)(F)F>>O=C(CC(F)(F)F)Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12 -US05254558,8,CC(C)C(NC(=O)Cn1c(-c2ccccc2)ncc(NC(=O)OCc2ccccc2)c1=O)C(O)C(F)(F)F>>CC(C)C(NC(=O)Cn1c(-c2ccccc2)ncc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F -US20110190137A1,2,CS(=O)(=O)Cl.OCCCCC1=CC1>>CS(=O)(=O)OCCCCC1=CC1 -US20060035912A1,1,COc1cc(C(=O)N(C)OC)cc(Cl)n1.N=C(c1ccccc1)c1ccccc1>>COc1cc(C(=O)N(C)OC)cc(N=C(c2ccccc2)c2ccccc2)n1 -US20060234997A1,6,COc1ccc2c(c1)NC(=O)NCC2>>O=C1NCCc2ccc(O)cc2N1 -US20090203717A1,6,CC(C)(C)OC(=O)NCC#CCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(F)(F)F)c4)c(Cl)c3)c21>>NCC#CCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(F)(F)F)c4)c(Cl)c3)c21 -US05350748,2,CC(C)Oc1c(C(=O)O)oc2ccc(Cl)cc12.NCc1ccccc1>>CC(C)Oc1c(C(=O)NCc2ccccc2)oc2ccc(Cl)cc12 -US07834051B2,7,CCC1C(=O)C(C)(C)C(=O)N1c1ccc(C#N)c(Cl)c1C>>CC[C@@H]1[C@H](O)C(C)(C)C(=O)N1c1ccc(C#N)c(Cl)c1C -US09005822B2,1,COCCOCCBr.COc1cc(C(C)(C)C)c(O)cc1C(C)(C)C>>COCCOCCOc1cc(C(C)(C)C)c(OC)cc1C(C)(C)C -US20150225354A1,2,CC(C)(C)OC(=O)CC1(CC(=O)OC(C)(C)C)CC(c2cc(O)ccc2CCC(=O)OCc2ccccc2)=NO1.N=C(N)Nc1ccc(C(=O)Cl)cc1>>CC(C)(C)OC(=O)CC1(CC(=O)OC(C)(C)C)CC(c2cc(OC(=O)c3ccc(NC(=N)N)cc3)ccc2CCC(=O)OCc2ccccc2)=NO1 -US20130053375A1,6,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc3nccc(Nc4ccc5scnc5c4)c3c2)CC1>>O=S(=O)(c1ccc2nccc(Nc3ccc4scnc4c3)c2c1)C1CCNCC1 -US03987047,2,CCCCCC(=O)Cl.Cc1c2c(nc3ccccc13)CCNCC2>>CCCCCC(=O)N1CCc2nc3ccccc3c(C)c2CC1 -US20080312192A1,7,CC(C)(C)CN1CCN(c2ccc([N+](=O)[O-])cc2C(F)(F)F)CC1>>CC(C)(C)CN1CCN(c2ccc(N)cc2C(F)(F)F)CC1 -US04692464,1,C1=COCCC1.O=C1C[C@H]2[C@H](C[C@@H](O)[C@@H]2COCc2ccccc2)O1>>O=C1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2COCc2ccccc2)O1 -US04308052,1,O=C(Cl)Cn1c(=O)sc2ccc(Cl)cc21.Sc1ccccc1>>O=C(Cn1c(=O)sc2ccc(Cl)cc21)Sc1ccccc1 -US20090247526A1,6,CC(C)(C)OC(=O)N1CCc2ncnc(Sc3cc(Nc4nc(CCc5ccccc5)cs4)ncc3Br)c2C1>>Brc1cnc(Nc2nc(CCc3ccccc3)cs2)cc1Sc1ncnc2c1CNCC2 -US20150197527A1,2,CCOC(=O)c1[nH]c2ccccc2c1N.S=C=Nc1cccc2ccccc12>>CCOC(=O)c1[nH]c2ccccc2c1NC(=S)Nc1cccc2ccccc12 -US20090105266A1,6,COC(=O)c1ccc(Nc2ccc(C)nc2)c(Cl)c1>>Cc1ccc(Nc2ccc(C(=O)O)cc2Cl)cn1 -US20050107377A1,1,C1CCNCC1.OCCCCl>>OCCCN1CCCCC1 -US04518597,7,CC(=O)Oc1cc(Cl)c2c(c1)COC(=O)N2>>O=C1Nc2c(Cl)cc(O)cc2CO1 -US20040176602A1,1,Cc1cc(N)ccc1OCc1ccccn1.N#Cc1cnc2cc(Br)ccc2c1Cl>>Cc1cc(Nc2c(C#N)cnc3cc(Br)ccc23)ccc1OCc1ccccn1 -US20020198197A1,1,CCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3nncc3CO)c1)=N2.NCC(F)(F)F>>CCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3nncc3CNCC(F)(F)F)c1)=N2 -US20140243374A1,2,COC(=O)c1ccc(CNC2CCCCC2F)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)c1ccc(CN(C2CCCCC2F)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US04182769,2,CCN(CC)C(=O)Cl.FC(F)C(F)(F)Sc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>CCN(CC)C(=O)n1c(SC(F)(F)C(F)F)nc(-c2ccccc2)c1-c1ccccc1 -US20130217702A1,6,CCOC(=O)c1c(Cl)c2ccccc2n1-c1ccc(CNC(=O)C2(NC(=O)c3cc(OC)no3)CC2)cc1>>COc1cc(C(=O)NC2(C(=O)NCc3ccc(-n4c(C(=O)O)c(Cl)c5ccccc54)cc3)CC2)on1 -US20130053563A1,1,CCC(CC)C(=O)O.COc1cc(OCCO)c(F)c(C(Nc2ccc(C(N)=NC(=O)OCC(C)(C)C)cc2)c2nc(OCCl)n(-c3ncccn3)n2)c1>>CCC(CC)C(=O)OCOc1nc(C(Nc2ccc(C(N)=NC(=O)OCC(C)(C)C)cc2)c2cc(OC)cc(OCCO)c2F)nn1-c1ncccn1 -US07781593B2,6,COC(=O)c1cnc(Cl)c(-c2ccc(Cl)cc2)c1>>O=C(O)c1cnc(Cl)c(-c2ccc(Cl)cc2)c1 -US08273774B2,6,CCOC(=O)c1csc(CC)n1>>CCc1nc(C(=O)O)cs1 -US08809538B2,1,O=C1c2ccc(Cl)cc2CCN1CC1CCNCC1.O=Cc1cc(-c2ccccc2)no1>>O=C1c2ccc(Cl)cc2CCN1CC1CCN(Cc2cc(-c3ccccc3)no2)CC1 -US04472381,6,COC(=O)[C@@H]1CCCN1C(=O)CNC(=O)OC(C)(C)C>>COC(=O)[C@@H]1CCCN1C(=O)CN -US20100035953A1,6,CCOC(=O)C(C)(C)Oc1ccc(OCc2cc(-c3ccc(OC(F)(F)F)cc3)nn2C)c(C)c1C>>Cc1c(OCc2cc(-c3ccc(OC(F)(F)F)cc3)nn2C)ccc(OC(C)(C)C(=O)O)c1C -US06376491B1,2,CCOC(=O)[C@@H]1N=C(c2oc3cccc(OCCCN(Cc4cccnc4)C(=O)OC(C)(C)C)c3c2C)O[C@H]1CC1CCCCC1.CN1CCNCC1>>Cc1c(C2=N[C@@H](C(=O)N3CCN(C)CC3)[C@H](CC3CCCCC3)O2)oc2cccc(OCCCN(Cc3cccnc3)C(=O)OC(C)(C)C)c12 -US06686475B2,1,O=Cc1ccc(F)cc1.OCCNc1ncccn1>>O=Cc1ccc(OCCNc2ncccn2)cc1 -US20120129855A1,2,FCC(CF)OC1CCNCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCC(OC(CF)CF)CC1 -US20110021532A1,3,CS(=O)(=O)c1ccc2nc(-c3ccc(Br)cc3)[nH]c2c1.Cc1cccc(B(O)O)c1>>Cc1cccc(-c2ccc(-c3nc4ccc(S(C)(=O)=O)cc4[nH]3)cc2)c1 -US20130178505A1,4,NC(=S)NN=C(Cc1ccccc1[N+](=O)[O-])C(=O)O.[N-]=[N+]=Nc1ccc(C(=O)CBr)cc1>>[N-]=[N+]=Nc1ccc(-c2csc(NN=C(Cc3ccccc3[N+](=O)[O-])C(=O)O)n2)cc1 -US20100144751A1,1,CC1(NC(=O)OCc2ccccc2)CCNCC1.COCCOc1ccn2c(-c3ccc4cc(F)cc(Br)c4n3)cnc2c1>>COCCOc1ccn2c(-c3ccc4cc(F)cc(N5CCC(C)(NC(=O)OCc6ccccc6)CC5)c4n3)cnc2c1 -US06114390,2,NC(=N[N+](=O)[O-])NCCC[C@@H](NC(=O)OCc1ccc2ccccc2c1)C(=O)O.NCc1ccc(CNC(N)=O)cc1>>NC(=O)NCc1ccc(CNC(=O)[C@@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)OCc2ccc3ccccc3c2)cc1 -US20080221105A1,6,CC(C)(C)OC(=O)N1CCC(NC(=O)Nc2ccc(C(F)(F)F)cc2)CC1>>O=C(Nc1ccc(C(F)(F)F)cc1)NC1CCNCC1 -US20140170110A1,6,COC(=O)c1cnc(OC)c([N+](=O)[O-])c1>>COc1ncc(C(=O)O)cc1[N+](=O)[O-] -US07704995B2,3,O=C1CCc2cc(Br)ccc21.OB(O)c1cccs1>>O=C1CCc2cc(-c3cccs3)ccc21 -US20060183909A1,7,COC(=O)c1cc(O)c2cc(C#Cc3ccccc3)cc(OC)c2n1>>COC(=O)c1cc(O)c2cc(CCc3ccccc3)cc(OC)c2n1 -US20080113963A1,2,Cc1nc2c3c(c(C(=O)O)cc2n1C)CCC(c1ccccc1)O3.NCCO>>Cc1nc2c3c(c(C(=O)NCCO)cc2n1C)CCC(c1ccccc1)O3 -US08497368B2,1,NCc1ccc2ncccc2c1.Nc1ncc(Br)nc1Br>>Nc1ncc(Br)nc1NCc1ccc2ncccc2c1 -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.COc1ccc(N=C=O)c(C)c1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)Nc3ccc(OC)cc3C)CC2)nc1C(F)(F)F -US06531596B1,6,CCOC(=O)C(Cc1ccc(OCCN2c3ccccc3Oc3ccccc32)c(I)c1)OCC>>CCOC(Cc1ccc(OCCN2c3ccccc3Oc3ccccc32)c(I)c1)C(=O)O -US20080176857A1,1,CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(Cl)nc2s1.NC(=O)CS>>CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(SCC(N)=O)nc2s1 -US20120322791A1,1,CC(C)(C)OC(=O)N1C2CCC1CNC2.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(Cl)nc2c(-c3ccc(-c4ccccc4)nc3)cnn12>>CC(C)(C)OC(=O)N1C2CCC1CN(c1cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(-c4ccc(-c5ccccc5)nc4)c3n1)C2 -US20130252943A1,1,CI.O=C1NCCc2nc(COc3ccccc3)oc21>>CN1CCc2nc(COc3ccccc3)oc2C1=O -US07132425B2,7,CS(=O)(=O)Nc1ccc([N+](=O)[O-])nc1>>CS(=O)(=O)Nc1ccc(N)nc1 -US09051323B2,6,CC(C)(C)OC(=O)NCCSc1ccc(C#N)cn1>>N#Cc1ccc(SCCN)nc1 -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(O)C(=O)NCCc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C(=O)NCCc4ccccc4)cc3)cc2)CC1 -US20130324555A1,6,CN(CC(=O)NNC(=O)OC(C)(C)C)C(=O)Oc1ccc(Cl)cc1C(=O)Nc1ccc([N+](=O)[O-])cc1Cl>>CN(CC(=O)NN)C(=O)Oc1ccc(Cl)cc1C(=O)Nc1ccc([N+](=O)[O-])cc1Cl -US05356893,2,CC(C)(C)N.Cc1cc(C(=O)O)ccc1Br>>Cc1cc(C(=O)NC(C)(C)C)ccc1Br -US20140235855A1,1,COc1ccc2ncc(Cl)c(CC(O)C(O)[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)c2c1>>COc1ccc2ncc3c(c2c1)CC(C(O)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1)O3 -US20120149682A1,7,COC(=O)c1cc(F)cc(OC2CCN(CC(CC#N)n3cc(-c4ncnc5c4ccn5COCC[Si](C)(C)C)cn3)CC2F)c1>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C(CC#N)CN4CCC(Oc5cc(F)cc(CO)c5)C(F)C4)c3)ncnc21 -US20090233929A1,3,COc1ccccc1-c1cccc(-n2cnc(C(=O)N(C)OC)c2)c1.Fc1ccc(Br)cc1>>COc1ccccc1-c1cccc(-n2cnc(C(=O)c3ccc(F)cc3)c2)c1 -US04143068,9,CCOc1ccc(C(=O)Cl)cc1.N#C[Cu]>>CCOc1ccc(C(=O)C#N)cc1 -US05455274,6,COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(C(N)=NO)cc1>>CC(C)N(C(=O)c1ccc(OCCCCCOc2ccc(C(N)=NO)cc2)c(O)c1)C(C)C -US20140155419A1,2,Cc1cc(Cl)ccc1C(N)c1ccccc1.Cc1ncccc1CNC1CCN(CC(=O)O)CC1>>Cc1cc(Cl)ccc1C(NC(=O)CN1CCC(NCc2cccnc2C)CC1)c1ccccc1 -US20140011777A1,7,Cc1nc(N(Cc2ccccc2)Cc2ccccc2)c([N+](=O)[O-])c(NCC2(O)CCCCC2)c1C>>Cc1nc(N(Cc2ccccc2)Cc2ccccc2)c(N)c(NCC2(O)CCCCC2)c1C -US20050239826A1,1,OC1(CNCCOc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)CC1.OCCCBr>>OCCCN(CCOc1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1)CC1(O)CC1 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1cc(C(F)(F)F)ccc1C(F)(F)F>>FC(F)(F)c1ccc(C(F)(F)F)c(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 -US20130172302A1,1,C1CCNCC1.O=C(O)C(Br)c1ccc(Cl)cc1>>O=C(O)C(c1ccc(Cl)cc1)N1CCCCC1 -US06303793B1,3,C#CCOCCO.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(I)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CCOCCO)c21 -US20120295903A1,1,CC(C)(C)OC(=O)CCN.Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN3CCC(C(=O)O)CC3)c2cc1Cl>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN3CCC(C(=O)O)CC3)c2cc1NCCC(=O)OC(C)(C)C -US20080090834A1,1,CN.O=Cc1ccc([N+](=O)[O-])cc1>>CNCc1ccc([N+](=O)[O-])cc1 -US07402672B2,1,CI.CNC(=O)c1[nH]c2cccnc2c1Sc1ccccc1>>CNC(=O)c1c(Sc2ccccc2)c2ncccc2n1C -US20150175562A1,6,CCOC(=O)c1nc(C(=O)N2CCC(C)CC2)c(-c2ccc(S(=O)(=O)NC(C)(C)CC)c(C)c2Cl)s1>>CCC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)O)nc2C(=O)N2CCC(C)CC2)c(Cl)c1C -US20110190269A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Cc1cc(Br)c2nc(N)nn2c1>>Cc1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)c2nc(N)nn2c1 -US20120315217A1,1,COc1ccc(C=O)cc1CCl.Cc1cccc(C)c1O>>COc1ccc(C=O)cc1COc1c(C)cccc1C -US20150111857A1,1,Brc1cnc(N2CCNCC2)nc1.CC(C)(C)OC(=O)N1CCO[C@H](Cn2cc(Nc3ncnc(Cl)n3)cn2)C1>>CC(C)(C)OC(=O)N1CCO[C@H](Cn2cc(Nc3ncnc(N4CCN(c5ncc(Br)cn5)CC4)n3)cn2)C1 -US20110190300A1,2,Nc1cccc(C(F)(F)F)c1.O=S(=O)(Cl)N1CCC2(CC1)OCCO2>>O=S(=O)(Nc1cccc(C(F)(F)F)c1)N1CCC2(CC1)OCCO2 -US20140323530A1,6,O=C(NCCC(O)c1cccc(C#CC2CCCCCC2)c1)C(F)(F)F>>NCCC(O)c1cccc(C#CC2CCCCCC2)c1 -US20100041892A1,4,CCOC(=O)CCc1cc(OCC(=O)NNC(C)=O)nn1Cc1ccc(Cl)cc1Cl>>CCOC(=O)CCc1cc(OCc2nnc(C)o2)nn1Cc1ccc(Cl)cc1Cl -US20090054435A1,2,CNOC.COCOc1cc(OC)ccc1C(=O)O>>COCOc1cc(OC)ccc1C(=O)N(C)OC -US06291457B1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CN(C(c2ccccc2)c2ccccc2)C1>>CCOC(=O)C=C1CN(C(c2ccccc2)c2ccccc2)C1 -US20100256356A1,2,COc1ccc(Cn2nc(NC3CCN(CCF)CC3)c3c(Oc4ccc(N)cc4F)ccnc32)cc1.O=C(O)c1ccnn(-c2ccc(F)cc2)c1=O>>COc1ccc(Cn2nc(NC3CCN(CCF)CC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1 -US20110082173A1,2,CCN(CC)C(=O)c1ccc(C(=C2CCN(Cc3cscn3)CC2)c2ccccc2N)cc1.COC(=O)Cl>>CCN(CC)C(=O)c1ccc(C(=C2CCN(Cc3cscn3)CC2)c2ccccc2NC(=O)OC)cc1 -US08124629B2,3,COC(=O)Cc1cc2ccc(F)cc2c(OS(=O)(=O)C(F)(F)F)c1C.Cc1ccc(CB2OC(C)(C)C(C)(C)O2)cc1>>COC(=O)Cc1cc2ccc(F)cc2c(Cc2ccc(C)cc2)c1C -US20040176361A1,1,CN(C)C1CCNCC1.O=c1[nH]c(Cl)cc2c(Br)cc(Cl)cc12>>CN(C)C1CCN(c2cc3c(Br)cc(Cl)cc3c(=O)[nH]2)CC1 -US20130237555A1,3,CC(=O)Nc1cc(Cl)c(C=O)cn1.COc1c(Cl)ccc(B2OC(C)(C)C(C)(C)O2)c1F>>COc1c(Cl)ccc(-c2cc(NC(C)=O)ncc2C=O)c1F -US20030153611A1,9,COc1ccc(C=C(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1NC(=O)[C@@](N)(CO)C(=O)OC(C)(C)C>>COc1ccc(C=C(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1NC(=O)[C@@H](N)CO -US20120115861A1,6,COc1ccc2nc(-c3cc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)nc4)cnc3N)[nH]c2c1>>COc1ccc2nc(-c3cc(-c4ccc(N5CCNCC5)nc4)cnc3N)[nH]c2c1 -US04500346,1,CC(Br)C(=O)OCCSCc1ccccc1.Oc1ccc(O)cc1>>CC(Oc1ccc(O)cc1)C(=O)OCCSCc1ccccc1 -US20150259359A1,1,CC(C)(CN)c1ncc(Cl)cc1F>>CC1(C)CNc2cc(Cl)cnc21 -US20100130538A1,3,CCOC(=O)/C=C/c1cccn2nc(C)nc12.C[S+](C)(C)=O>>CCOC(=O)C1CC1c1cccn2nc(C)nc12 -US08969583B2,7,COCCCNC(=O)Nc1snc(-c2ccc([N+](=O)[O-])cc2)c1C(N)=O>>COCCCNC(=O)Nc1snc(-c2ccc(N)cc2)c1C(N)=O -US20150141400A1,2,CCSc1ccc(Cl)cc1CN.Nc1c(Br)cc(OC(F)(F)F)cc1C(=O)O>>CCSc1ccc(Cl)cc1CNC(=O)c1cc(OC(F)(F)F)cc(Br)c1N -US04557753,1,BrCc1ccccc1.Cc1c(Cl)ccc(C(=O)c2cnn(C)c2O)c1Cl>>Cc1c(Cl)ccc(C(=O)c2cnn(C)c2OCc2ccccc2)c1Cl -US07169777B2,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCN(C(CN)c2ccccc2Cl)CC1>>CC(=O)NCC(c1ccccc1Cl)N1CCN(C(=O)OC(C)(C)C)CC1 -US08211901B2,2,NCc1ccc(C(=O)Nc2ccccc2N)cc1.O=C(O)c1cccc2cc(Oc3ccnc4cc(Cl)ccc34)ccc12>>Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2cccc3cc(Oc4ccnc5cc(Cl)ccc45)ccc23)cc1 -US08673942B2,1,COC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)nc3)cc(O)c2[nH]1.COCC(O)COC>>COCC(COC)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C(=O)OC)[nH]c12 -US20130324516A1,1,Fc1cc(Br)ccn1.NCCN1CCCC1>>Brc1ccnc(NCCN2CCCC2)c1 -US20150148308A1,4,CCSc1ccccc1C(=O)O.Nc1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1N>>CCSc1ccccc1-c1nc2cc(C(F)(C(F)(F)F)C(F)(F)F)ccc2[nH]1 -US20040006099A1,6,CCOC(=O)C1(COc2ccc3c(c2)CN(C(=N)N)CCC3)CCN(c2ccncc2)CC1>>N=C(N)N1CCCc2ccc(OCC3(C(=O)O)CCN(c4ccncc4)CC3)cc2C1 -US08952010B2,6,COc1ccc2ncc(=O)n(CCCCOCc3ccccc3)c2n1>>COc1ccc2ncc(=O)n(CCCCO)c2n1 -US08945897B2,9,COC(=O)CCCCCCCCCCCCCCCN=[N+]=[N-]>>COC(=O)CCCCCCCCCCCCCCCN -US20100075998A1,9,CCOC(=O)c1c(Br)[nH]c2c1CCc1cnccc1-2>>CCOC(=O)c1c[nH]c2c1CCc1cnccc1-2 -US20140057953A1,6,COc1cccc(CN(C)S(=O)(=O)c2ccc(Br)s2)c1>>CN(Cc1cccc(O)c1)S(=O)(=O)c1ccc(Br)s1 -US20130190290A1,6,COc1ccc(Cn2cc(-c3cc4n(-c5cc(NC(=O)c6cc(N7CCN(C)CC7)cc(C(C)(C)C)c6)ccc5C)ccn4n3)cn2)cc1>>Cc1ccc(NC(=O)c2cc(N3CCN(C)CC3)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12 -US20090181963A1,2,CCC(=O)Cl.Oc1cccc(-c2nc(N3CCOCC3)c3nnn(CCN4CCNCC4)c3n2)c1>>CCC(=O)N1CCN(CCn2nnc3c(N4CCOCC4)nc(-c4cccc(O)c4)nc32)CC1 -US20050059685A1,1,BrCc1ccccc1.CC(=O)O[C@H](C)CCCCn1c(=O)c2c(=O)cc(C)[nH]c2n(C)c1=O>>CC(=O)O[C@H](C)CCCCn1c(=O)c2c(=O)cc(C)n(Cc3ccccc3)c2n(C)c1=O -US08937041B2,6,CCOC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)c1cc(C)on1)C(=O)N1C[C@H](Oc3nc4ccccc4c4ccccc34)C[C@H]1C(=O)N2>>Cc1cc(C(=O)N[C@H]2CCCCCC=C[C@@H]3C[C@@]3(C(=O)O)NC(=O)[C@@H]3C[C@@H](Oc4nc5ccccc5c5ccccc45)CN3C2=O)no1 -US05559106,2,CCOP(=O)(CC(=O)Cl)OCC.NNc1nc2ccc(C(F)(F)F)cc2n(OCc2ccccc2)c1=O>>CCOP(=O)(CC(=O)NNc1nc2ccc(C(F)(F)F)cc2n(OCc2ccccc2)c1=O)OCC -US20120316161A1,3,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.OB(O)c1ccc(Cl)cc1F>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(Cl)cc1F -US20120208827A1,6,CC(C)(C)OC(=O)N1CCC(CNC(=O)C(F)(F)F)C1>>CC(C)(C)OC(=O)N1CCC(CN)C1 -US04165371,1,C=O.c1ccc2c(c1)C1CCNCC2C1>>CN1CCC2CC(C1)c1ccccc12 -US20140235628A1,6,CC(C)(C)OC(=O)N1CCC(O)(C#C[Si](C)(C)C)CC1>>C#CC1(O)CCN(C(=O)OC(C)(C)C)CC1 -US07544835B2,2,COC(=O)C(Cc1ccc(OC)c(CO)c1)C(=O)OC.Cc1ccc(N=C=O)cc1>>COC(=O)C(Cc1ccc(OC)c(COC(=O)Nc2ccc(C)cc2)c1)C(=O)OC -US20150209358A1,2,CCn1cc(C(=O)O)c(=O)n(-c2ccc(F)cc2)c1=O.COc1cc2nccc(Oc3ccc(N)cc3F)c2cc1OC>>CCn1cc(C(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O -US20140057937A1,2,CCC(C(=O)O)n1nc(C(F)(F)F)c(Cl)c1C.Fc1ccc(-n2ncc3c2CCCN3)cc1>>CCC(C(=O)N1CCCc2c1cnn2-c1ccc(F)cc1)n1nc(C(F)(F)F)c(Cl)c1C -US06498151B2,10,COP(=O)(OC)c1cc(-c2ccc(C)cc2)ccc1OC(C)C1CCCC1.O=C1CCC(=O)N1Br>>COP(=O)(OC)c1cc(-c2ccc(CBr)cc2)ccc1OC(C)C1CCCC1 -US20050267095A1,7,COc1ccc(C2(C(=O)N3CCOCC3)CCOCC2)cc1>>COc1ccc(C2(CN3CCOCC3)CCOCC2)cc1 -US20150252030A1,1,COC(=O)CBr.Cc1cc(-c2cncnc2)cc(C)c1O>>COC(=O)COc1c(C)cc(-c2cncnc2)cc1C -US08377942B2,9,NO.O=Cc1ccc(Br)c2ccccc12>>ON=Cc1ccc(Br)c2ccccc12 -US20060100201A1,1,C1CCNCC1.O=[N+]([O-])c1ccc(F)cc1F>>O=[N+]([O-])c1ccc(F)cc1N1CCCCC1 -US06638929B2,2,CCO.O=C(O)CC[N+](=O)[O-]>>CCOC(=O)CC[N+](=O)[O-] -US20050239802A1,3,CCOC(=O)c1cc(Br)ccc1F.OB(O)C1=C(c2cc(Cl)ccc2OCc2ccc(F)cc2)CCC1>>CCOC(=O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccc(F)cc3)CCC2)ccc1F -US20080070928A1,2,CS(=O)(=O)Cl.Fc1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2C2CCCN2)cc1>>CS(=O)(=O)N1CCCC1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(F)cc1 -US05563142,1,O=[N+]([O-])c1cccnc1Cl.OCCO>>O=[N+]([O-])c1cccnc1OCCO -US20040006134A1,3,N#Cc1ccc(Br)cc1Cl.OB(O)c1ccc(F)cc1F>>N#Cc1ccc(-c2ccc(F)cc2F)cc1Cl -US05563143,1,COc1ccc(C2CNC(=O)NC2)cc1O.OCCCCc1ccccc1>>COc1ccc(C2CNC(=O)NC2)cc1OCCCCc1ccccc1 -US20120245210A1,3,COc1cc(Cl)ccc1B(O)O.Cc1cc(NS(C)(=O)=O)ccc1-c1c(Br)csc1C=O>>COc1cc(Cl)ccc1-c1csc(C=O)c1-c1ccc(NS(C)(=O)=O)cc1C -US20140323468A1,7,CC(C)(C)OC(=O)N1CCCc2cc(-c3cncc(C=CCS(C)(=O)=O)c3)cnc21>>CC(C)(C)OC(=O)N1CCCc2cc(-c3cncc(CCCS(C)(=O)=O)c3)cnc21 -US20100298311A1,1,CC[C@H](C[C@@](O)(C=O)C(F)(F)F)c1ccc(F)c(Cl)c1OC.Nc1cccc2[nH]c(=O)ccc12>>CC[C@H](C[C@@](O)(C=Nc1cccc2[nH]c(=O)ccc12)C(F)(F)F)c1ccc(F)c(Cl)c1OC -US08183262B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1cc(-c2cc(C(F)(F)F)nc(-c3cccc(Br)c3)n2)ccc1Cl>>Cc1cc(-c2cc(C(F)(F)F)nc(-c3cccc(-c4ccc(N)nc4)c3)n2)ccc1Cl -US20150011528A1,6,CCOC(=O)Cn1c(=NC(=O)c2ccc(C)cc2)sc2c(F)c(F)ccc21>>Cc1ccc(C(=O)N=c2sc3c(F)c(F)ccc3n2CC(=O)O)cc1 -US20110003820A1,2,CC1NCCn2cc(-c3ccc(F)nc3)nc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2nc(-c3ccc(F)nc3)cn2CCN1C(=O)c1cc2ncc(Br)cn2n1 -US20060040986A1,2,COc1cc(-c2cc(CN3CCC(N)CC3)ccn2)cc(OC)c1OC.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>COc1cc(-c2cc(CN3CCC(NS(=O)(=O)c4ccccc4[N+](=O)[O-])CC3)ccn2)cc(OC)c1OC -US07576080B2,2,NCC(N)=O.O=C(O)c1cccc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1>>NC(=O)CNC(=O)c1cccc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1 -US20020032351A1,6,COC(=O)C(c1ccc(Cl)cc1)C1CC1>>O=C(O)[C@@H](c1ccc(Cl)cc1)C1CC1 -US08809336B2,1,Clc1ncnc2[nH]ccc12.NC1(c2ccc(Cl)cc2)CCNCC1>>NC1(c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 -US20050288339A1,9,Cc1ccc(O[C@H](C(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)[C@H](O)c2ccc(O)cc2)cc1>>Cc1ccc(O[C@@H](Cc2ccc(O)cc2)C(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)cc1 -US07514449B2,2,CNCCN(C)C.COC(=O)[C@@H]1CC[C@@H](C(=O)O)CC1>>COC(=O)[C@@H]1CC[C@@H](C(=O)N(C)CCN(C)C)CC1 -US06403584B1,2,CC(C)(C)OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1.O=S(=O)(Cl)C(F)(F)F>>CC(C)(C)OC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)NC(=O)OCc1ccccc1 -US08242116B2,1,Cc1ccc(Cl)nn1.NCc1ccccc1>>Cc1ccc(NCc2ccccc2)nn1 -US07105567B2,2,CC(C)c1cccc(C(C)C)c1N=C=O.Cc1ccc(NCc2ccc(N(C)C)cc2)c(C)c1>>Cc1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)Nc2c(C(C)C)cccc2C(C)C)c(C)c1 -US20050075375A1,9,FC(F)(F)c1cccnc1Cl>>FC(F)(F)c1cccnc1 -US20120264735A1,1,CCI.Oc1cnc2ccc(Cl)cc2c1>>CCOc1cnc2ccc(Cl)cc2c1 -US08389555B2,8,OCCN1CCc2ccccc2C1>>O=CCN1CCc2ccccc2C1 -US05807885,7,N=C(Nc1ccc([N+](=O)[O-])cc1)c1ccccc1>>N=C(Nc1ccc(N)cc1)c1ccccc1 -US20090143354A1,1,N[C@@H]1CCNC1.O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(Cl)ccc12>>N[C@@H]1CCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)C1 -US20120029026A1,7,CNc1cc(Oc2ccnc(OC)c2)ccc1[N+](=O)[O-]>>CNc1cc(Oc2ccnc(OC)c2)ccc1N -US20090042954A1,3,O=C(O)c1ccc(B(O)O)cc1.O=S(=O)(OC1=CCC2(CC1)OCCO2)C(F)(F)F>>O=C(O)c1ccc(C2=CCC3(CC2)OCCO3)cc1 -US20110130380A1,9,C[C@H]1CC(CNc2cccc(-c3cc(F)ncc3Cl)n2)C[C@@H](C)O1.[NH4+]>>C[C@H]1CC(CNc2cccc(-c3cc(N)ncc3Cl)n2)C[C@@H](C)O1 -US08846709B2,1,COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(Cl)n([C@H](C)c3ccccc3)c12.NCCO>>COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(NCCO)n([C@H](C)c3ccccc3)c12 -US20150005281A1,1,CC(C)(C)OC(=O)N1C[C@@H](F)C[C@H]1CN.Cc1cnc(Cl)nc1Cl>>Cc1cnc(Cl)nc1NC[C@@H]1C[C@H](F)CN1C(=O)OC(C)(C)C -US20100261727A1,1,Clc1ccc(Cl)nn1.OCCF>>FCCOc1ccc(Cl)nn1 -US20140288123A1,1,CCc1cccc(O)c1Br.COC(=O)c1ccc(F)c(C)c1>>CCc1cccc(Oc2ccc(C(=O)OC)cc2C)c1Br -US08252935B2,6,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(C(c3ccccc3)c3ccccc3)C2)c1>>CC(C)CC(C(=O)O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(C(c3ccccc3)c3ccccc3)C2)c1 -US20130336918A1,7,O=C(Nc1cnc(-c2cccc(C(F)(F)F)c2)cn1)c1cc(N2CCCCC2)ccc1[N+](=O)[O-]>>Nc1ccc(N2CCCCC2)cc1C(=O)Nc1cnc(-c2cccc(C(F)(F)F)c2)cn1 -US07553867B2,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1ccc2cc(OCc3ccccc3)ccc2c1>>CCOC(=O)/C=C/c1ccc2cc(OCc3ccccc3)ccc2c1 -US20090181952A1,1,C1=COCCC1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OC2CCCCO2)cc1 -US20140031374A1,2,Nc1ccccc1Cl.O=C(Cl)c1ccc(Cl)cc1Cl>>O=C(Nc1ccccc1Cl)c1ccc(Cl)cc1Cl -US20130217702A1,6,COC(=O)c1c(Cl)c2c(F)cccc2n1-c1ccc(CNC(=O)OC(C)(C)C)cc1>>COC(=O)c1c(Cl)c2c(F)cccc2n1-c1ccc(CN)cc1 -US05059597,2,CCOC(=O)Cl.c1ccc(CN2CC3CCNC3C2)cc1>>CCOC(=O)N1CCC2CN(Cc3ccccc3)CC21 -US08058283B2,6,C[Si](C)(C)C#Cc1ccccc1Cl>>C#Cc1ccccc1Cl -US20110183976A1,1,C1COCCN1.O=C1OCC(Br)=C1Br>>O=C1OCC(N2CCOCC2)=C1Br -US08309734B2,2,Cc1ccc2c(c1)CCCN2.O=C(O)c1cccnc1Oc1ccc(F)c(Cl)c1>>Cc1ccc2c(c1)CCCN2C(=O)c1cccnc1Oc1ccc(F)c(Cl)c1 -US20080305169A1,2,Nc1cc(C(F)(F)F)ccc1O.O=C(Cl)CCl>>O=C(CCl)Nc1cc(C(F)(F)F)ccc1O -US20130090342A1,1,Nc1ccc(Br)cc1.O=[N+]([O-])c1cccc(Cl)c1F>>O=[N+]([O-])c1cccc(Cl)c1Nc1ccc(Br)cc1 -US20060148858A1,6,COC(=O)Cc1cccc(OC)c1OCCCc1cn(-c2cccc(C(F)(F)F)n2)nc1C(C)C>>COc1cccc(CC(=O)O)c1OCCCc1cn(-c2cccc(C(F)(F)F)n2)nc1C(C)C -US20040122057A1,1,CNC(=O)CCl.COc1cc(F)c(C(OC)C(=O)NCc2ccc(C#N)cc2O)c(F)c1>>CNC(=O)COc1cc(C#N)ccc1CNC(=O)C(OC)c1c(F)cc(OC)cc1F -US05216150,1,ClCC=Cc1ccc(Cl)cc1.Nc1ccccc1N>>Nc1ccccc1NCC=Cc1ccc(Cl)cc1 -US05610153,1,CC(C)(C)OC(=O)N[C@H]1COc2ccccc2NC1=O.CC(C)c1ccc(CCl)cc1>>CC(C)c1ccc(CN2C(=O)[C@H](NC(=O)OC(C)(C)C)COc3ccccc32)cc1 -US20030134884A1,2,CCOC(=O)O[C@H](CCCc1ccc(OCc2nc(-c3ccccc3)sc2C)cc1)C(N)=O>>Cc1sc(-c2ccccc2)nc1COc1ccc(CCC[C@H]2OC(=O)NC2=O)cc1 -US04024128,2,CCCCNC(=O)N1CCc2ccc(S(N)(=O)=O)cc2CC1.O=C=NC1CCCCC1>>CCCCNC(=O)N1CCc2ccc(S(=O)(=O)NC(=O)NC3CCCCC3)cc2CC1 -US08269008B2,3,CCCC[Sn](CCCC)(CCCC)CCCC.COC(=O)c1nc(Br)c2nc(-c3ccccc3)oc2c1O>>CCCCc1nc(C(=O)OC)c(O)c2oc(-c3ccccc3)nc12 -US20040077671A1,2,CNC.O=C(N1CCc2ccc(S(=O)(=O)Cl)cc2C1)C(F)(F)F>>CN(C)S(=O)(=O)c1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2 -US09133168B2,2,CC1(C)CNc2cccc(F)c21.Cn1c(CC(=O)[O-])nc(N2CCOCC2)cc1=O>>Cn1c(CC(=O)N2CC(C)(C)c3c(F)cccc32)nc(N2CCOCC2)cc1=O -US06436953B1,1,CCO.Cc1nc2c3c(ccn2c1C)[C@@H](O)[C@H](O)[C@@H](c1ccccc1)N3>>CCO[C@@H]1c2ccn3c(C)c(C)nc3c2N[C@H](c2ccccc2)[C@H]1O -US20090176786A1,8,C#CCSc1ccc(N(C)C(=O)NC(=O)c2c(F)cccc2F)c(F)c1.O=C(OO)c1cccc(Cl)c1>>C#CCS(=O)c1ccc(N(C)C(=O)NC(=O)c2c(F)cccc2F)c(F)c1 -US06479506B1,1,Cn1ncnc1CCl.Oc1nc2c(cc1Br)nnn2-c1ccccc1F>>Cn1ncnc1COc1nc2c(cc1Br)nnn2-c1ccccc1F -US05049671,1,NCCO.Nc1nc(Cl)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1>>Nc1nc(NCCO)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1 -US20130150325A1,2,C1CCNC1.Cc1cc(/C(F)=C/c2ccc(SC(F)(F)F)cc2)nn1Cc1cccc(C(=O)O)c1>>Cc1cc(/C(F)=C/c2ccc(SC(F)(F)F)cc2)nn1Cc1cccc(C(=O)N2CCCC2)c1 -US20090239941A1,6,CCC(=O)Oc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(N)=O)cc1OC(=O)CC>>CCC(=O)Oc1ccc(C[C@H]([NH3+])C(N)=O)cc1OC(=O)CC -US08754077B2,7,C[C@@H]1COCCN1C(=O)c1ccc(Nc2cc(-c3ccnc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3C=O)cn(C)c2=O)nc1>>C[C@@H]1COCCN1C(=O)c1ccc(Nc2cc(-c3ccnc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3CO)cn(C)c2=O)nc1 -US07109360B1,1,CO[C@H]1C[C@]2(C)C(=O)CC[C@H]2[C@@H]2CCc3cc(O)ccc3[C@@H]12.Cc1ccc(S(=O)(=O)NN)cc1>>CO[C@H]1C[C@]2(C)C(=NNS(=O)(=O)c3ccc(C)cc3)CC[C@H]2[C@@H]2CCc3cc(O)ccc3[C@@H]12 -US07378417B2,2,CC(C)(CO)NS(=O)(=O)c1cccc(N)c1.CCOc1cc(-c2cc(C(F)F)n3ncc(C(=O)O)c3n2)ccc1C(F)(F)F>>CCOc1cc(-c2cc(C(F)F)n3ncc(C(=O)Nc4cccc(S(=O)(=O)NC(C)(C)CO)c4)c3n2)ccc1C(F)(F)F -US20130012489A1,6,CC(C)(C)OC(=O)N1CCCC(Cc2nc3ccccc3s2)C1>>c1ccc2sc(CC3CCCNC3)nc2c1 -US20140178304A1,6,COc1cn(-c2ccc(-n3cc(F)c(F)c3)cc2OCc2ccccc2)nc(-c2ccnn2-c2ccccc2)c1=O>>COc1cn(-c2ccc(-n3cc(F)c(F)c3)cc2O)nc(-c2ccnn2-c2ccccc2)c1=O -US20060287297A1,6,COc1cccc2c(=O)c3ccccc3oc12>>O=c1c2ccccc2oc2c(O)cccc12 -US05041432,7,CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C#N)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](OC(=O)c2ccccc2)C(C)(C)[C@@H]1CC3>>CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C#N)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3 -US20140249132A1,1,CCC(C)=O.COc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C)c1C1CNC1>>CCC(C)N1CC(c2c(C)c(Cl)cc(C(C)n3nc(C)c4c(N)ncnc43)c2OC)C1 -US20100168077A1,1,CC(C)(C)OC(=O)NC1CCCN1c1cc(Cl)nc(Cl)c1.COc1ccc(CN)cc1>>COc1ccc(CNc2cc(N3CCCC3NC(=O)OC(C)(C)C)cc(Cl)n2)cc1 -US04528296,6,CCOC(=O)c1ccc(NC(=O)C(C)CSC(C)=O)nc1>>CCOC(=O)c1ccc(NC(=O)C(C)CS)nc1 -US08546387B2,2,CC(C)(C)c1cc(N=C=O)n(-c2ccccc2)n1.CN1CCN(c2cnc3c(Oc4ccc(N)c(F)c4)ccnc3n2)CC1>>CN1CCN(c2cnc3c(Oc4ccc(NC(=O)Nc5cc(C(C)(C)C)nn5-c5ccccc5)c(F)c4)ccnc3n2)CC1 -US20080176916A1,1,COC(=O)CNS(=O)(=O)c1ccc(OCC2CC2)cc1.ClCc1ccc(-n2nccn2)cc1>>COC(=O)CN(Cc1ccc(-n2nccn2)cc1)S(=O)(=O)c1ccc(OCC2CC2)cc1 -US05123951,2,CCOC(=O)C(OCC)C(=O)[O-].Nc1ccc(Br)cc1>>CCOC(=O)C(OCC)C(=O)Nc1ccc(Br)cc1 -US20150057273A1,1,CC(C)(C)c1cc(N)n(-c2cccc(O)c2)n1.CN(C)CCO>>CN(C)CCOc1cccc(-n2nc(C(C)(C)C)cc2N)c1 -US20060063784A1,1,CNC.O=Cc1ccc(-c2cccc(-c3ccnc4c(C(=O)c5cccs5)cnn34)c2)cc1>>CN(C)Cc1ccc(-c2cccc(-c3ccnc4c(C(=O)c5cccs5)cnn34)c2)cc1 -US20150175604A1,1,Clc1ccc2[nH]c(Br)cc2n1.Clc1cccc(CBr)c1>>Clc1cccc(Cn2c(Br)cc3nc(Cl)ccc32)c1 -US20060183909A1,6,COC(=O)c1cc(O)c2cc(Br)cc(OCc3ccccc3)c2n1>>COC(=O)c1cc(O)c2cc(Br)cc(O)c2n1 -US04198420,3,CC(=O)N1CCC(C(=O)Cl)(c2ccccc2Sc2ccccc2)CC1>>CC(=O)N1CCC2(CC1)C(=O)c1ccccc1Sc1ccccc12 -US05475106,2,COc1ccccc1N(CC(=O)OC(C)(C)C)C(=O)CN.Cc1cccc(N=C=O)c1>>COc1ccccc1N(CC(=O)OC(C)(C)C)C(=O)CNC(=O)Nc1cccc(C)c1 -US20150266879A1,6,COc1ccccc1NC(=O)[C@@H]1Cc2cccnc2N1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)C>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ncccc2C[C@H]1C(=O)Nc1ccccc1OC)C(C)C -US08222254B2,2,CC(=O)OC(C)=O.Cn1nc(CCN2CCN(c3cccc(N)c3)CC2)n(CC2CCCCC2)c1=O>>CC(=O)Nc1cccc(N2CCN(CCc3nn(C)c(=O)n3CC3CCCCC3)CC2)c1 -US05633255,6,CCCn1c(=O)c(NC(=O)OC(C)(C)C)nc2ccccc21>>CCCn1c(=O)c(N)nc2ccccc21 -US20110130394A1,1,COc1ccc2cnc(N)cc2c1.Clc1cc(CN2CCCC2)ccn1>>COc1ccc2cnc(Nc3cc(CN4CCCC4)ccn3)cc2c1 -US20110224272A1,2,CC(=O)S[C@@H](CC(C)C)C(=O)O.CCOc1nc(CC)c(CN)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1F>>CCOc1nc(CC)c(CNC(=O)[C@H](CC(C)C)SC(C)=O)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1F -US20150018343A1,6,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1CO[C@H]1CCCN(C(=O)OC(C)(C)C)C1)C3>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1CO[C@H]1CCCNC1)C3 -US04337353,7,Cc1c(C=CCCCC(=O)O)cccc1C(=O)c1ccc(Cl)cc1>>Cc1c(CCCCCC(=O)O)cccc1C(=O)c1ccc(Cl)cc1 -US20030176495A1,1,CC1(C)OC(=O)C(=CC(=O)Cl)O1.CONCc1ccc(OC)cc1>>COc1ccc(CN(OC)C(=O)C=C2OC(C)(C)OC2=O)cc1 -US07125896B2,1,C1CCNC1.Clc1ccc(I)cn1>>Ic1ccc(N2CCCC2)nc1 -US20100144745A1,2,CS(=O)(=O)Cl.C[Si](C)(C)CCOCn1ccc2nc(NC(=O)NC3CCCNC3)cnc21>>C[Si](C)(C)CCOCn1ccc2nc(NC(=O)N[C@@H]3CCCN(S(C)(=O)=O)C3)cnc21 -US08318949B2,1,CC(=O)c1sc(N2CCNC2=O)nc1C.Fc1ccc(CBr)cc1>>CC(=O)c1sc(N2CCN(Cc3ccc(F)cc3)C2=O)nc1C -US20110251194A1,2,NCc1cccnc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(NCc1cccnc1)Oc1ccc([N+](=O)[O-])cc1 -US05861359,1,COC(=O)C(C)Oc1cc(Cl)ccc1CCl.Cn1nc(-c2ccc(O)cc2)c(Cl)c1OC(F)F>>COC(=O)C(C)Oc1cc(Cl)ccc1COc1ccc(-c2nn(C)c(OC(F)F)c2Cl)cc1 -US08389527B2,1,NC1CC1.O=C(Nc1ccncc1F)c1cnc2c(Br)cc(Cl)nn12>>O=C(Nc1ccncc1F)c1cnc2c(NC3CC3)cc(Cl)nn12 -US20140134133A1,3,COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1NS(=O)(=O)c1ccc(F)cc1F.C[Si](C)(C)C#Cc1cnc2ccc(Br)nn12>>COc1ncc(-c2ccc3ncc(C#C[Si](C)(C)C)n3n2)cc1NS(=O)(=O)c1ccc(F)cc1F -US06127386,1,C=O.COCCOc1cncc(OC[C@@H]2CCCN2)c1>>COCCOc1cncc(OC[C@@H]2CCCN2C)c1 -US06018046,1,O=c1ccn2c3ccc(Br)cc3c3cc(O)cc1c32.OCCCCCl>>O=c1ccn2c3ccc(Br)cc3c3cc(OCCCCO)cc1c32 -US20050131014A1,1,COc1ccc(OC)c(C=O)c1.Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>COc1ccc(OC)c(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 -US07572791B2,2,CO.O=C(O)c1cccc(Cc2ccccc2)c1O>>COC(=O)c1cccc(Cc2ccccc2)c1O -US06093838,1,CC(C)c1cc(N)cc2c1OCC2(C)C.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(Nc2cc(C(C)C)c3c(c2)C(C)(C)CO3)cc1 -US05663440,3,CCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(c1ccccc1)c1ccccc1>>CCCCCC=C(c1ccccc1)c1ccccc1 -US05328911,1,COC(=O)c1ccccc1-c1ccc(CBr)cc1.Cc1ccnc2[nH]c(C3CC3)nc12>>COC(=O)c1ccccc1-c1ccc(Cn2c(C3CC3)nc3c(C)ccnc32)cc1 -US08673891B2,3,C[C@H](Nc1nc(Cl)cc(Cl)n1)c1ccc(F)cc1.OB(O)c1cncnc1>>C[C@H](Nc1nc(Cl)cc(-c2cncnc2)n1)c1ccc(F)cc1 -US08410107B2,2,Nc1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1.O=C(O)C1CCCO1>>O=C(Nc1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1)C1CCCO1 -US20100010045A1,6,CCOC(=O)c1cc(CO)n(Cc2cc(-c3ccc(Cl)s3)on2)n1>>O=C(O)c1cc(CO)n(Cc2cc(-c3ccc(Cl)s3)on2)n1 -US20020045747A1,2,CC1C=CC2=C(C1=O)C(N)CC(C)(C)C=N2.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>CC1C=CC2=C(C1=O)C(NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1)CC(C)(C)C=N2 -US20070129416A1,2,CC(=O)NCCN1CCNCC1.CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)Cl>>CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCNC(C)=O)CC1 -US07592342B2,3,CC1(C)OB(c2cncc(NS(=O)(=O)c3ccccc3)c2)OC1(C)C.CS(=O)(=O)CCNC1CCN(c2cnc3ccc(Br)cc3n2)CC1>>CS(=O)(=O)CCNC1CCN(c2cnc3ccc(-c4cncc(NS(=O)(=O)c5ccccc5)c4)cc3n2)CC1 -US04636513,2,C1CCNCC1.Cc1oncc1C(=O)O>>Cc1oncc1C(=O)N1CCCCC1 -US08071592B2,1,CC(C)(C)OC(=O)NC1CCNCC1.COc1ccc2nnc(=O)n(CC=O)c2c1>>COc1ccc2nnc(=O)n(CCN3CCC(NC(=O)OC(C)(C)C)CC3)c2c1 -US20040002524A1,6,O=C(NCc1ccccc1)c1ccc(-c2nc3ccccc3n2-c2ccc(OC3CCCCO3)cc2)cc1>>O=C(NCc1ccccc1)c1ccc(-c2nc3ccccc3n2-c2ccc(O)cc2)cc1 -US20040259912A1,1,COC(=O)c1cc([N+](=O)[O-])ccc1O.OC(c1ccccc1)c1ccc(F)cc1>>COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccccc1)c1ccc(F)cc1 -US05344843,6,COC(=O)C(=O)c1ccc(OCCCCOc2ccccc2)cc1>>O=C(O)C(=O)c1ccc(OCCCCOc2ccccc2)cc1 -US20150210720A1,7,CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(OC3COC3)n2)CC1>>CC(=O)N1CCN(c2ccc(N)c(OC3COC3)n2)CC1 -US09062055B2,1,CC(=O)c1cc2cccnc2n1-c1cccc(F)c1.[NH4+]>>CC(N)c1cc2cccnc2n1-c1cccc(F)c1 -US20120232111A1,2,COc1ccccc1C(=O)Cl.NCCC(=O)O>>COc1ccccc1C(=O)NCCC(=O)O -US20150105366A1,8,COc1nc2ccc(C(O)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1>>COc1nc2ccc(C(=O)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 -US06143764,2,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C=NC1CCCCC1>>COc1cc2nccc(Oc3ccc(NC(=O)NC4CCCCC4)cc3)c2cc1OC -US20140057896A1,3,CC(=O)OCc1c(Br)cc(F)cc1N1CCn2c(cc3c2C2CCC3C2)C1=O.Cn1cc(B2OC(C)(C)C(C)(C)O2)cc(Nc2ccncn2)c1=O>>CC(=O)OCc1c(-c2cc(Nc3ccncn3)c(=O)n(C)c2)cc(F)cc1N1CCn2c(cc3c2C2CCC3C2)C1=O -US20050014812A1,1,CCOc1ccc(Cn2c(C)nc3c(C)cc(CO)cc32)c(Cl)c1.COC(=O)c1ccccc1O>>CCOc1ccc(Cn2c(C)nc3c(C)cc(COc4ccccc4C(=O)OC)cc32)c(Cl)c1 -US08399505B2,2,CC(C)(C)OC(=O)/C=C/c1cc[nH]c1.O=S(=O)(Cl)c1cccc(-c2ccccc2)c1>>CC(C)(C)OC(=O)/C=C/c1ccn(S(=O)(=O)c2cccc(-c3ccccc3)c2)c1 -US20140378487A1,7,O=Cc1ccc(Oc2cccc(C(F)(F)F)c2)cc1>>OCc1ccc(Oc2cccc(C(F)(F)F)c2)cc1 -US06057369,8,COc1ccc(SC(CCCCc2ccccc2)CC(=O)NO)cc1OC.O=C(OO)c1cccc(Cl)c1>>COc1ccc(S(=O)C(CCCCc2ccccc2)CC(=O)NO)cc1OC -US20090163488A1,2,Cc1cc(NC(=O)c2cc(C)nn2C)cc(Oc2ccc3nc(N)nn3c2)c1.O=C(Cl)C1CC1>>Cc1cc(NC(=O)c2cc(C)nn2C)cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1 -US20120270865A2,6,CCOC(=O)CCNC(=O)c1ccc(NC(CC(C)C)c2oc3ccc(OC)cc3c2C)cc1>>COc1ccc2oc(C(CC(C)C)Nc3ccc(C(=O)NCCC(=O)O)cc3)c(C)c2c1 -US20110200586A1,1,CC(Br)C(N)=O.CN(C1=NC(=O)C(=Cc2ccc3c(cnn3Cc3ccc(C(F)(F)F)cc3C(F)(F)F)c2)S1)C1CCNCC1>>CC(C(N)=O)N1CCC(N(C)C2=NC(=O)C(=Cc3ccc4c(cnn4Cc4ccc(C(F)(F)F)cc4C(F)(F)F)c3)S2)CC1 -US04433152,1,N=C(N)N1CCC(CCC(=O)O)CC1.Oc1ccc(-c2ccccc2)cc1>>N=C(N)N1CCC(CCC(=O)Oc2ccc(-c3ccccc3)cc2)CC1 -US20090286765A1,1,N#Cc1ccc(F)cc1.Sc1c[nH]nn1>>N#Cc1ccc(Sc2c[nH]nn2)cc1 -US20110006295A1,3,Cc1ccc2cc(Br)ccc2n1.OB(O)c1ccc2ccc3cccc4ccc1c2c34>>Cc1ccc2cc(-c3ccc4ccc5cccc6ccc3c4c56)ccc2n1 -US20050043336A1,1,Fc1cccc(COc2ccc(Nc3ncnc4cccc(OC5CCNCC5)c34)cc2Cl)c1.NC(=O)CCl>>NC(=O)CN1CCC(Oc2cccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c23)CC1 -US20090291988A1,3,CC1(C)OB(c2ccc(C3(C(N)=O)CC3)cc2)OC1(C)C.NC(c1ccc(Br)cc1)c1ccc(F)cc1F>>NC(=O)C1(c2ccc(-c3ccc(C(N)c4ccc(F)cc4F)cc3)cc2)CC1 -US20120121540A1,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.COC(=O)c1cn2cc(Br)cc(C(F)(F)F)c2n1>>COC(=O)c1cn2cc(-c3cnn(C(=O)OC(C)(C)C)c3)cc(C(F)(F)F)c2n1 -US04318914,2,O=S(=O)(Cl)C(F)(F)F.OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>O=S(=O)(OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F -US20040209921A1,2,CC(C)(C)c1ccnc(CN(Cc2ccc(CN)cc2CO)C2CCCc3cccnc32)c1.O=C(O)C1Cc2ccccc2CN1>>CC(C)(C)c1ccnc(CN(Cc2ccc(CNC(=O)C3Cc4ccccc4CN3)cc2CO)C2CCCc3cccnc32)c1 -US04029801,2,NC1CCN(Cc2ccccc2)CC1.O=C(Cl)c1ccc(Cl)cc1>>O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 -US06251928B1,3,CC(C)(C)c1ccc(COc2ccc(C=O)cc2)cc1.O=C1CSC(=S)N1>>CC(C)(C)c1ccc(COc2ccc(C=C3SC(=S)NC3=O)cc2)cc1 -US08153623B2,1,CC(C)(C)OC(=O)N1[C@@H](c2ccc(OCc3ccccc3F)cc2)CC[C@]12CCNC2=O.CI>>CN1CC[C@]2(CC[C@H](c3ccc(OCc4ccccc4F)cc3)N2C(=O)OC(C)(C)C)C1=O -US20130225810A1,2,CN.O=C(O)c1ccc(I)c([N+](=O)[O-])c1>>CNC(=O)c1ccc(I)c([N+](=O)[O-])c1 -US20140213599A1,1,C[C@H]1Cn2c(cc(Cl)nc2=O)N1C.OCc1cc(F)c(F)cc1F>>C[C@H]1Cn2c(cc(OCc3cc(F)c(F)cc3F)nc2=O)N1C -US20120302566A1,3,C[Mg+].O=C(O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(C(=O)C5CCOCC5)cccc43)ccc21>>CC(O)(c1cccc2c1CC[C@H]2Oc1ccc2c(c1)OC[C@H]2CC(=O)O)C1CCOCC1 -US20150057265A1,2,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2N)C1.COCc1cnc2c(C(=O)O)c(NC(=O)OC(C)(C)C)sc2c1>>COCc1cnc2c(C(=O)Nc3cnccc3N3CCC[C@H](NC(=O)OC(C)(C)C)C3)c(NC(=O)OC(C)(C)C)sc2c1 -US20150141400A1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1.CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(C=O)c(C(F)(F)F)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CC[C@H](NC(=O)OC(C)(C)C)C3)c(C(F)(F)F)cc2c1=O -US20080194629A1,2,COCCCCC1(CNC(=O)[C@H]2C[C@H](C(=O)O)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21.NCCc1ccccc1>>COCCCCC1(CNC(=O)[C@H]2C[C@H](C(=O)NCCc3ccccc3)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21 -US06034121,1,CCCCS.CCCc1c(Cl)c2cc(Br)ccc2oc1=O>>CCCCSc1c(CCC)c(=O)oc2ccc(Br)cc12 -US20100298324A1,2,CN(C)c1cccc(CN)c1.COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)n1>>COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)NCc4cccc(N(C)C)c4)ccc3c2=O)n1 -US20060205772A1,2,C1CCC2NCCCC2C1.Nc1ccc(C(=O)O)cc1[N+](=O)[O-]>>Nc1ccc(C(=O)N2CCC[C@@H]3CCCC[C@H]32)cc1[N+](=O)[O-] -US20110076291A1,2,O=C(C1CCCO1)N1CCNCC1.O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2>>O=C(c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2)N1CCN(C(=O)[C@H]2CCCO2)CC1 -US20030229074A1,1,COc1ccccc1CN.O=[N+]([O-])c1ccccc1F>>COc1ccccc1CNc1ccccc1[N+](=O)[O-] -US20040138223A1,1,CC(C)c1ccc(NC(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1.CCc1nc(CCl)cs1>>CCc1nc(CN(C(=O)C2CCCc3c(OCc4ccccc4)cccc32)c2ccc(C(C)C)nc2)cs1 -US05665718,1,COCCNCCOC.O=C1c2c(Cl)cccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCN12>>COCCN(CCOC)Cc1nc(-c2ncn3c2[C@@H]2CCN2C(=O)c2c(Cl)cccc2-3)no1 -US20130237537A1,2,CC(C)c1cccc(N)c1.O=C(O)c1cncc(Br)c1>>CC(C)c1cccc(NC(=O)c2cncc(Br)c2)c1 -US20140057990A1,6,CC(=O)N[C@@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21>>N[C@@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21 -US20150018547A1,7,CCc1nc(C)ccc1C(=O)OC>>CCc1nc(C)ccc1CO -US09115093B2,1,CS(=O)(=O)CCBr.N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)(F)F)c3)C3=C2C(=O)CCC3)cc1>>CS(=O)(=O)CCN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1 -US20130040930A1,1,CC1(C)NC(=O)NC1=O.CI>>CN1C(=O)NC(C)(C)C1=O -US07645756B2,6,COc1ccc(-c2nn3cnnc3c3ccccc23)cn1>>Oc1ccc(-c2nn3cnnc3c3ccccc23)cn1 -US08431695B2,3,CC(C)(C)OC(=O)N1CCN(c2cccc(-c3cc(Br)c4c(N)ncnn34)c2)CC1.CC1(C)OB(c2ccc3cn(Cc4ccccc4)nc3c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCN(c2cccc(-c3cc(-c4ccc5cn(Cc6ccccc6)nc5c4)c4c(N)ncnn34)c2)CC1 -US20070149577A1,2,COc1ncc(F)cc1-c1ccc(C(C)N)cc1.Cn1cc(S(=O)(=O)Cl)c(C(F)(F)F)n1>>COc1ncc(F)cc1-c1ccc(C(C)NS(=O)(=O)c2cn(C)nc2C(F)(F)F)cc1 -US07576212B2,3,CC(=O)c1ccccc1.CCOC(=O)CC#N>>CCOC(=O)C(C#N)=C(C)c1ccccc1 -US20080051405A1,6,CC(C)(C)OC(=O)N1CCC(Oc2cccc(Cn3ncc4cc(-c5ccc(Cl)cc5)sc4c3=O)n2)CC1>>O=c1c2sc(-c3ccc(Cl)cc3)cc2cnn1Cc1cccc(OC2CCNCC2)n1 -US20080004270A1,7,Nc1c([N+](=O)[O-])cc[nH]c1=O>>Nc1cc[nH]c(=O)c1N -US20130225620A1,7,N#Cc1cc(F)cc2[nH]ccc12>>NCc1cc(F)cc2[nH]ccc12 -US20140213570A1,3,CC1(C)OB(c2cn[nH]c2)OC1(C)C.COc1cc(Br)cc(OC)c1-c1ccc(N(C)C2CC(C)(C)NC(C)(C)C2)nn1>>COc1cc(-c2cn[nH]c2)cc(OC)c1-c1ccc(N(C)C2CC(C)(C)NC(C)(C)C2)nn1 -US20140005146A1,1,C[C@@H](Nc1c(C(N)=O)cnn2cc(Br)cc12)C1CC1.O=C1CCCN1>>C[C@@H](Nc1c(C(N)=O)cnn2cc(N3CCCC3=O)cc12)C1CC1 -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1N1CCc2ccccc2C1>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1N1CCc2ccccc2C1 -US07547779B2,7,O=[N+]([O-])c1cnc(Br)cc1Nc1ccccc1>>Nc1cnc(Br)cc1Nc1ccccc1 -US20120095020A1,4,Brc1ccc2c(c1)C=CCC2.O=C(OO)c1cccc(Cl)c1>>Brc1ccc2c(c1)[C@@H]1O[C@@H]1CC2 -US20040220193A1,1,CC(C)C(C#N)(CCCI)c1ccc(C#N)s1.FC(F)(F)c1ccc(OCCN2CCNCC2)nc1>>CC(C)C(C#N)(CCCN1CCN(CCOc2ccc(C(F)(F)F)cn2)CC1)c1ccc(C#N)s1 -US20020128494A1,6,CCOc1ccc2c(=O)cc(-c3ccccc3OC)oc2c1>>CCOc1ccc2c(=O)cc(-c3ccccc3O)oc2c1 -US20150133438A1,6,C[C@H]1SC(NC(=O)c2ccccc2)=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](c3ncco3)C[C@@H]12>>C[C@H]1SC(N)=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](c3ncco3)C[C@@H]12 -US04962234,7,CCOC(=O)c1cccc(N=C(C)c2ccccc2)c1>>CCOC(=O)c1cccc(NC(C)c2ccccc2)c1 -US08586591B2,7,COC(=O)c1cc(Nc2cnccn2)nc(N[C@@H](C)c2ccc(F)cc2)c1>>C[C@H](Nc1cc(CO)cc(Nc2cnccn2)n1)c1ccc(F)cc1 -US09120749B2,3,CC(C)(C)OC(=O)NC(C)(C)c1ccc(Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)cc1.CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C>>CC(C)(C)OC(=O)NC(C)(C)c1ccc(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(Cl)c4)cc23)cc1 -US20070254866A1,7,CCOC(=O)c1c(C)n(C2CC2)c2c(OC)c(F)c(F)c([N+](=O)[O-])c2c1=O>>CCOC(=O)c1c(C)n(C2CC2)c2c(OC)c(F)c(F)c(N)c2c1=O -US20100152160A1,6,CN(C)c1cc2c(cc1Cl)N(C(=O)OC(C)(C)C)CC(C(=O)N1CCC(C#N)(Cc3ccc(F)nc3)CC1)O2>>CN(C)c1cc2c(cc1Cl)NCC(C(=O)N1CCC(C#N)(Cc3ccc(F)nc3)CC1)O2 -US20140155389A1,1,COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1nc(Cl)cc2cn[nH]c(=O)c12.Nc1cc(Cl)cc(Cl)c1>>COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1nc(Nc2cc(Cl)cc(Cl)c2)cc2cn[nH]c(=O)c12 -US06436925B1,2,CCOC(=O)c1cccc(N)c1.O=S(=O)(Cl)c1ccc2ccccc2c1>>CCOC(=O)c1cccc(NS(=O)(=O)c2ccc3ccccc3c2)c1 -US20130338398A1,6,CCCCC(=O)CC(=O)c1ccc(OCc2ccccc2)cc1>>CCCCC(=O)CC(=O)c1ccc(O)cc1 -US20120040954A1,1,CC(C)(C)[Si](C)(C)OCCBr.Cc1cc(C)cc(O)c1>>Cc1cc(C)cc(OCCO[Si](C)(C)C(C)(C)C)c1 -US20070060567A1,6,CCOC(=O)c1ccc(NC(=O)c2cc(OC)c3c(c2)N(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC3)cc1F>>COc1cc(C(=O)Nc2ccc(C(=O)O)c(F)c2)cc2c1CCN2S(=O)(=O)c1cccc(C(F)(F)F)c1 -US20150072969A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=S1(=O)CCC(CO)CC1>>Cc1ccc(S(=O)(=O)OCC2CCS(=O)(=O)CC2)cc1 -US20150166480A1,2,CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)O)cc3F)cc2F)CC1.O[C@H]1CCCNC1>>CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)N4CCC[C@H](O)C4)cc3F)cc2F)CC1 -US04104375,2,Cc1noc(N)c1C.O=C(CCl)OC(=O)CCl>>Cc1noc(NC(=O)CCl)c1C -US20150119385A1,6,COCCNc1cc(NC(=O)N2CCCc3cc(CO[Si](C)(C)C(C)(C)C)c(C(OC)OC)nc32)ncc1C#N>>COCCNc1cc(NC(=O)N2CCCc3cc(CO)c(C(OC)OC)nc32)ncc1C#N -US08507484B2,1,CN1CCC(=O)CC1.Cc1cc(C)c2nc(C)n(Cc3ccc(NCC4CCNCC4)cc3)c2n1>>Cc1cc(C)c2nc(C)n(Cc3ccc(NCC4CCN(C5CCN(C)CC5)CC4)cc3)c2n1 -US20130274241A1,7,CN1C2CCC1CC(n1cc([N+](=O)[O-])cn1)C2>>CN1C2CCC1CC(n1cc(N)cn1)C2 -US20050113340A1,2,CC(=O)OC(C)=O.COc1cc(Cn2cnc3c(Cl)nc(N)nc32)c(Br)c(OC)c1OC>>COc1cc(Cn2cnc3c(Cl)nc(NC(C)=O)nc32)c(Br)c(OC)c1OC -US05817664,3,C#C[Si](C)(C)C.O=c1[nH]cc(I)c(=O)[nH]1>>C[Si](C)(C)C#Cc1c[nH]c(=O)[nH]c1=O -US07235548B2,2,CC(C)CC(N)C(=O)O.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>CC(C)CC(NS(=O)(=O)c1ccccc1[N+](=O)[O-])C(=O)O -US04159331,1,CCCOc1cc(F)cc(NC(=O)N2CCN(S(=O)(=O)c3ccc(N)cc3)CC2)c1.Clc1ccc2c(Cl)ccnc2c1>>CCCOc1cc(F)cc(NC(=O)N2CCN(S(=O)(=O)c3ccc(Nc4ccnc5cc(Cl)ccc45)cc3)CC2)c1 -US20040048788A1,2,C=CC(=O)O.O=C1N[C@@H](Cc2ccccc2)CO1>>C=CC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20060160794A1,2,CN.O=S(=O)(Cl)c1ccccc1Cl>>CNS(=O)(=O)c1ccccc1Cl -US06608070B1,2,NCCO.O=C(O)Cc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12>>O=C(Cc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12)NCCO -US20050171161A1,2,Cc1ccc(-c2nc(C(=O)O)n(C)c2-c2ccc(C)cc2)cc1.NN1CCCCC1>>Cc1ccc(-c2nc(C(=O)NN3CCCCC3)n(C)c2-c2ccc(C)cc2)cc1 -US08637501B2,1,Cn1c2c(c3ccc(Br)cc31)CN(C(=O)OC(C)(C)C)CCC2.O=c1cc(OCc2ccc(Cl)cn2)cc[nH]1>>Cn1c2c(c3ccc(-n4ccc(OCc5ccc(Cl)cn5)cc4=O)cc31)CN(C(=O)OC(C)(C)C)CCC2 -US20130344030A1,6,C=CC1(C(=O)OCC)COC(CF)(CF)OC1>>C=CC1(C(=O)O)COC(CF)(CF)OC1 -US20130158009A1,1,Cc1cc(O)c(F)cc1Br.O=C1OCC[C@H]1O>>Cc1cc(O[C@H]2CCOC2=O)c(F)cc1Br -US07851473B2,1,Fc1ccc(-c2nsc(Cl)n2)cc1.O=C(Nc1noc2ccccc12)N1CCNCC1>>O=C(Nc1noc2ccccc12)N1CCN(c2nc(-c3ccc(F)cc3)ns2)CC1 -US20100063077A1,1,Clc1ncc(Br)cn1.Nc1cccc(OCc2ccccc2)c1>>Brc1cnc(Nc2cccc(OCc3ccccc3)c2)nc1 -US20150232420A1,6,C=CC(=O)NCCC1C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1>>C=CC(=O)NCCC1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1 -US05763437,6,COC(=O)c1cccc(NC(=O)NC2N=C(c3ccccc3F)c3ccccc3N(CC(=O)N3CC4CCC(CC4)C3)C2=O)c1>>O=C(Nc1cccc(C(=O)O)c1)NC1N=C(c2ccccc2F)c2ccccc2N(CC(=O)N2CC3CCC(CC3)C2)C1=O -US04816560,1,C=C(C)C.C[C@H](O)[C@@H](N)C(=O)NC(=O)OCc1ccccc1>>C[C@H](OC(C)(C)C)[C@@H](N)C(=O)NC(=O)OCc1ccccc1 -US20050245563A1,2,Cc1[nH]nc2c1c(=O)n(CCCN)c1ccc(C#CCN3CCCC3)cc21.O=C(Cl)c1ccc(Cl)cc1>>Cc1[nH]nc2c1c(=O)n(CCCNC(=O)c1ccc(Cl)cc1)c1ccc(C#CCN3CCCC3)cc21 -US20010031788A1,7,CCOC(=O)CC(NC(=O)C(Cl)c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1>>CCOC(=O)CC(NC(=O)C(Cl)c1ccc(Cl)cc1)c1cccc(N)c1 -US20110190280A1,6,CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2F)CC1>>O=[N+]([O-])c1ccc(OC2CCNCC2)c(F)c1 -US08507690B2,1,CC(=O)Nc1nc(C(=O)O)cs1.CC(C)(C)OC(=O)NNC(=O)OCCc1ccc(O)cc1>>CC(=O)Nc1nc(C(=O)Oc2ccc(CCOC(=O)NNC(=O)OC(C)(C)C)cc2)cs1 -US06984657B1,1,CCOC(=O)c1cc2cc(OC(C)=O)ccc2[nH]1.Clc1ccc(CBr)cc1I>>CCOC(=O)c1cc2cc(OC(C)=O)ccc2n1Cc1ccc(Cl)c(I)c1 -US07989449B2,1,CCOc1ccc(C2(c3cccc(Br)c3)COC(N)=N2)cc1C.COc1cccc(N)c1>>CCOc1ccc(C2(c3cccc(Nc4cccc(OC)c4)c3)COC(N)=N2)cc1C -US05258544,8,Cc1cc(C2=CC(C)(C)CC(C)(C)C2CO)ccc1F>>Cc1cc(C2=CC(C)(C)CC(C)(C)C2C=O)ccc1F -US20100029636A1,1,CCBr.CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCNCC5)c4)cnn3c2N)cc1>>CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCN(CC)CC5)c4)cnn3c2N)cc1 -US20150218096A1,1,COC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(Br)ccc23)c(F)c1.O=C1NCCN1>>COC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(N4CCNC4=O)ccc23)c(F)c1 -US08349880B2,5,O=C(O)CCCC(=O)c1ccccc1.OCCO>>O=C(O)CCCC1(c2ccccc2)OCCO1 -US20060287373A1,2,CC(C(=O)O)c1ccc(Br)cc1.CCOC(=O)[C@H](C)O>>CCOC(=O)[C@H](C)OC(=O)[C@@H](C)c1ccc(Br)cc1 -US08268859B2,7,CC(C)(CC(=O)C(F)(F)F)c1ccccc1Br>>CC(C)(CC(O)C(F)(F)F)c1ccccc1Br -US08969388B1,9,Cc1c(C(=O)Nc2ccc(Oc3ccnc(C(N)=O)c3)c(Cl)c2)c(=O)n(-c2ccccc2)n1C>>Cc1c(C(=O)Nc2ccc(Oc3ccnc(N)c3)c(Cl)c2)c(=O)n(-c2ccccc2)n1C -US08304371B2,2,CS(=O)(=O)Cl.OCc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12>>CS(=O)(=O)OCc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12 -US05155113,2,CCOCn1cc(Cl)c(O)cc1=O.O=C(Cl)c1ccccc1>>CCOCn1cc(Cl)c(OC(=O)c2ccccc2)cc1=O -US08288566B2,2,CCOC(=O)/C=C/C(C)O.O=C=NC1CCCCC1>>CCOC(=O)/C=C/C(C)OC(=O)NC1CCCCC1 -US07189712B2,6,COc1cccc(-c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)o2)c1>>CN1CCN(c2ccc(Nc3ncc(-c4cccc(O)c4)o3)cc2)CC1 -US08138175B2,7,COC(=O)C(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N1CCN(c2cccc(C(F)(F)F)c2)C(C)C1=O>>CC1C(=O)N(C(CO)CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CCN1c1cccc(C(F)(F)F)c1 -US20110212918A1,5,COC(=O)c1cc(N)cnc1SCc1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(NC(=O)C(F)(F)F)cnc1SCc1ccccc1 -US07714161B2,2,C=Cc1ccc(O)cc1.O=C(Cl)CCl>>C=Cc1ccc(OC(=O)CCl)cc1 -US08034812B2,1,Cc1nc2cc(O)ccc2n1C.O=C(Nc1cn2nc(I)ccc2n1)C1CC1>>Cc1nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2n1C -US20150065482A1,3,C#C[Mg]Br.COC(=O)C(=O)C(CN(C)C(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C>>C#CC(O)(C(=O)OC)C(CN(C)C(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C -US06329380B1,2,CN(c1nccc(-n2cnc3ccccc32)n1)C1CCCNC1.O=C=Nc1ccccc1>>CN(c1nccc(-n2cnc3ccccc32)n1)C1CCCN(C(=O)Nc2ccccc2)C1 -US08071824B2,7,CC(C)(C)C(O)Cc1ccccc1[N+](=O)[O-]>>CC(C)(C)C(O)Cc1ccccc1N -US06803381B1,2,CCCc1cnc(N)o1.O=C(O)C(c1ccccc1)c1ccccc1>>CCCc1cnc(NC(=O)C(c2ccccc2)c2ccccc2)o1 -US20120245137A1,2,CS(=O)(=O)Cl.O=S(=O)(c1cccc(C(F)(F)F)c1)C1CCC(O)CC1>>CS(=O)(=O)OC1CCC(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 -US04728653,2,CCOC(=O)/C=C/c1cc(-n2ncnn2)cc(C)c1N>>Cc1cc(-n2ncnn2)cc2ccc(=O)[nH]c12 -US20050130941A1,6,CC(C)(C)OC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1>>NC(=O)C[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)O -US20150252047A1,1,CC(C)Oc1cc2[nH]ncc2cc1N.CCc1[nH]c2ncnc(Cl)c2c1C>>CCc1[nH]c2ncnc(Nc3cc4cn[nH]c4cc3OC(C)C)c2c1C -US20090036450A1,6,CCOC(=O)c1nc(CNC(=O)OCc2ccccc2)[nH]c1C>>CCOC(=O)c1nc(CN)[nH]c1C -US04006145,1,O=C(O)c1cc(Br)ccc1I.Sc1ccccc1>>O=C(O)c1cc(Br)ccc1Sc1ccccc1 -US20060058314A1,9,CC(=O)OC[C@H]1CN(c2ccc(I)c(F)c2)C(=O)O1>>CC(=O)OC[C@H]1CN(c2cccc(F)c2)C(=O)O1 -US20150087664A1,2,COc1ccc([C@H](N)c2cnn(C)c2)cc1F.O=C(O)c1cc(F)c2cnc(NCC3CC3)nc2c1>>COc1ccc([C@H](NC(=O)c2cc(F)c3cnc(NCC4CC4)nc3c2)c2cnn(C)c2)cc1F -US08410107B2,7,O=[N+]([O-])c1cnc(OCC2CC2)c(Br)c1>>Nc1cnc(OCC2CC2)c(Br)c1 -US20080139558A1,1,Clc1ccccc1-c1nc2ccccc2[nH]1.O=c1cc(CBr)c2ccc(F)c(F)c2[nH]1>>O=c1cc(Cn2c(-c3ccccc3Cl)nc3ccccc32)c2ccc(F)c(F)c2[nH]1 -US20070249670A1,6,COC(=O)[C@@H]1CCCCN1C(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C>>Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N2CCCC[C@H]2C(=O)O)c(C)c1 -US20150218173A1,2,C1CCNCC1.O=C(O)c1[nH]c2ncnc(Nc3ccc4[nH]ncc4c3)c2c1Br>>O=C(c1[nH]c2ncnc(Nc3ccc4[nH]ncc4c3)c2c1Br)N1CCCCC1 -US20090227799A1,1,Nc1nc(Cl)ccc1C(=O)O.OCCO>>Nc1nc(OCCO)ccc1C(=O)O -US20080249093A1,6,COC(=O)c1cnc(OC(C)C(F)(F)F)c(C#N)c1>>CC(Oc1ncc(C(=O)O)cc1C#N)C(F)(F)F -US20120101082A1,6,Cc1cc(C(=O)N2CCc3nc(C)n(Cc4ccccc4)c3-c3ccccc32)ccc1OCCCN1CCN(CCC(C)(C)C)CC1>>Cc1nc2c([nH]1)-c1ccccc1N(C(=O)c1ccc(OCCCN3CCN(CCC(C)(C)C)CC3)c(C)c1)CC2 -US07943651B2,1,Cc1cc(Br)c(C=NNc2cccc(C(=O)O)c2)c(Br)c1>>Cc1cc(Br)c2cnn(-c3cccc(C(=O)O)c3)c2c1 -US05780466,1,CC(=O)NC1(c2ccccc2)CCNCC1.CS(=O)(=O)OCCC1(c2ccc(Cl)c(Cl)c2)CN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(=O)O1>>CC(=O)NC1(c2ccccc2)CCN(CCC2(c3ccc(Cl)c(Cl)c3)CN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C(=O)O2)CC1 -US20060024330A1,1,CC(C)(C)OC(=O)N1CCNC(=O)C1.N#Cc1cccc(CBr)c1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(C#N)c2)C(=O)C1 -US20110294850A1,2,O=C=Nc1ccc([N+](=O)[O-])cc1.Oc1ccc2c(c1)CCN2Cc1ccccc1>>O=C(Nc1ccc([N+](=O)[O-])cc1)Oc1ccc2c(c1)CCN2Cc1ccccc1 -US06900224B2,6,C[C@H]1[C@H](NC(=O)OC(C)(C)C)CN(Cc2ccccc2)CC1(C)C>>C[C@H]1[C@H](NC(=O)OC(C)(C)C)CNCC1(C)C -US03970704,3,CC(C)=CCCC(C)CC=O.C[Mg+]>>CC(C)=CCCC(C)CC(C)O -US20090029947A1,6,CCCCCCCCc1ccc([C@H]2CC[C@@](CCP(=O)(OCC)OCC)(NC(=O)OC(C)(C)C)C2)cc1>>CCCCCCCCc1ccc([C@H]2CC[C@](N)(CCP(=O)(OCC)OCC)C2)cc1 -US04552892,2,CC1(C)[C@@H](C(=O)Cl)[C@@H]1C=C(F)F.OCc1c(F)c(F)c(F)c(-c2ccccc2)c1F>>CC1(C)[C@@H](C(=O)OCc2c(F)c(F)c(F)c(-c3ccccc3)c2F)[C@@H]1C=C(F)F -US05872138,1,C=CCBr.COC(=O)c1ccc(O)cc1>>C=CCOc1ccc(C(=O)OC)cc1 -US05409943,2,Nc1ncccc1OCc1c(F)ccc(F)c1F.S=C=Nc1ccc(Cl)cc1>>Fc1ccc(F)c(COc2cccnc2NC(=S)Nc2ccc(Cl)cc2)c1F -US20080318943A1,3,COc1ccncc1B(O)O.Nc1c2c(nc3c(Br)cccc13)CN(C1CCC1)C2=O>>COc1ccncc1-c1cccc2c(N)c3c(nc12)CN(C1CCC1)C3=O -US20100041654A1,2,NCC1CCCCC1.O=C(Cl)c1cnc(Cl)nc1C(F)(F)F>>O=C(NCC1CCCCC1)c1cnc(Cl)nc1C(F)(F)F -US05061720,1,CCOC(=O)Cc1ccc(OCCCCl)c(OC)c1.O=C1NC(=O)c2ccccc21>>CCOC(=O)Cc1ccc(OCCCN2C(=O)c3ccccc3C2=O)c(OC)c1 -US20090149439A1,2,COc1ccc(S(=O)(=O)C(c2cnc(C(=O)O)cc2C)c2cc(F)ccc2F)cc1F.NCCO>>COc1ccc(S(=O)(=O)C(c2cnc(C(=O)NCCO)cc2C)c2cc(F)ccc2F)cc1F -US20090054411A1,1,CC(C)Oc1cc([N+](=O)[O-])ccc1Cl.CN1CCNCC1>>CC(C)Oc1cc([N+](=O)[O-])ccc1N1CCN(C)CC1 -US20130203732A1,7,Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2NC(=O)OC(C)(C)C)c1C1CCC(=O)CC1>>Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2NC(=O)OC(C)(C)C)c1C1CCC(O)CC1 -US05059708,3,CCOP(=O)(Cc1ccc2ccc3cccc4ccc1c2c34)OCC.O=Cc1ccc(Cl)cc1>>Clc1ccc(C=Cc2ccc3ccc4cccc5ccc2c3c45)cc1 -US20100298373A1,6,Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)OC(C)(C)C)C2CCCC(=O)O>>Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCNC2CCCC(=O)O -US20110245255A1,1,CCN1CCN(c2nc(C)nc3[nH]c(-c4ccccc4Cl)nc23)CC1.COCBr>>CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3COC)CC1 -US20120309750A1,3,CCCC[Sn](CCCC)(CCCC)c1cnn(C(C)C)c1.CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1I>>CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1cnn(C(C)C)c1 -US07138414B2,2,NC(=O)C1CCCN(c2ccc(F)cc2N)C1.O=C=NC(=O)c1cc(F)c(F)cc1Cl>>NC(=O)C1CCCN(c2ccc(F)cc2NC(=O)NC(=O)c2cc(F)c(F)cc2Cl)C1 -US20110257151A1,2,CC(C)N1CCN(c2cc(F)cc(C3Nc4ccc(C(=O)O)cc4CC3(C)C)c2)CC1.CS(N)(=O)=O>>CC(C)N1CCN(c2cc(F)cc(C3Nc4ccc(C(=O)NS(C)(=O)=O)cc4CC3(C)C)c2)CC1 -US05064844,1,CI.OCc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1>>COCc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1 -US20110178064A1,3,C[C@H]1CN(c2ncc(B3OC(C)(C)C(C)(C)O3)cc2C=O)C[C@@H](C)O1.Cc1ccc(Br)s1>>Cc1ccc(-c2cnc(N3C[C@H](C)O[C@H](C)C3)c(C=O)c2)s1 -US05994398,1,CCCCCCCCCCl.CNc1ccc(S(=O)(=O)Nc2ccccc2)cc1>>CCCCCCCCCN(C)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 -US20060122234A1,2,COC(=O)c1ccc(-c2ccn(CC(=O)Nc3ccccc3)n2)s1.NO>>O=C(Cn1ccc(-c2ccc(C(=O)NO)s2)n1)Nc1ccccc1 -US20130158075A1,2,COC(=O)C1CCC(c2ncc(-c3ccc(N)cc3)s2)CC1.O=C=Nc1cccc(Cl)c1F>>COC(=O)C1CCC(c2ncc(-c3ccc(NC(=O)Nc4cccc(Cl)c4F)cc3)s2)CC1 -US20100029713A1,1,Fc1ccc(CBr)cc1F.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>O=C(O[C@H]1C[N+]2(Cc3ccc(F)c(F)c3)CCC1CC2)C1(c2ccccc2)CCCCCC1 -US09108984B2,7,COC(=O)c1cc(Cl)c(C#C[Si](C)(C)C)c([N+](=O)[O-])c1-c1cccc(F)c1>>COC(=O)c1cc(Cl)c(C#C[Si](C)(C)C)c(N)c1-c1cccc(F)c1 -US07528136B2,1,COC(=O)C1CC(=O)CN1Cc1ccccc1.NCc1ccccc1>>COC(=O)C1CC(NCc2ccccc2)CN1Cc1ccccc1 -US20050032838A1,2,CSc1cccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@H](N)CC2)c1.O=C(O)C1CCC1>>CSc1cccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@H](NC(=O)C3CCC3)CC2)c1 -US20110207935A1,1,CCOC(=O)c1cc[nH]n1.N#Cc1cc(Br)cc2ccccc12>>CCOC(=O)c1ccn(-c2cc(C#N)c3ccccc3c2)n1 -US20110207716A1,6,CC[C@@H]1C(=O)N(C)c2cnc(-c3ccncc3NC(=O)OC(C)(C)C)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(-c3ccncc3N)nc2N1C1CCCC1 -US05466705,1,CC1(C(=O)Cl)CCCCC1.CCOC(=N)c1c(F)cccc1Cl>>CCOC(=NC(=O)C1(C)CCCCC1)c1c(F)cccc1Cl -US20130059849A1,2,CC(C)n1ncc2c(C(=O)O)cc(-c3ccncc3)nc21.Cc1cc(-c2ccccc2)c(CN)c(=O)[nH]1>>Cc1cc(-c2ccccc2)c(CNC(=O)c2cc(-c3ccncc3)nc3c2cnn3C(C)C)c(=O)[nH]1 -US08044207B2,3,Brc1cccc(Br)n1.CON(C)C(=O)C1CCN(C)CC1>>CN1CCC(C(=O)c2cccc(Br)n2)CC1 -US20080176862A1,7,CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2ccc(F)c(C3=CCCCC3)c2)N=C1N>>CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2ccc(F)c(C3CCCCC3)c2)N=C1N -US07268128B2,3,CN(C)C=O.COc1cc(Br)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1>>COc1cc(C=O)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1 -US07834019B2,7,CC(=O)c1cccc(Br)n1>>CC(O)c1cccc(Br)n1 -US20090233930A9,3,Brc1cccc(I)c1.C#Cc1ccc2c(c1)CCC(OC)C2>>COC1CCc2cc(C#Cc3cccc(Br)c3)ccc2C1 -US20150148334A1,1,C1COCCN1.O=C1NCCC(c2ccc(Cl)c(Cl)c2)c2cc(I)sc21>>O=C1NCCC(c2ccc(Cl)c(Cl)c2)c2cc(N3CCOCC3)sc21 -US05652250,6,COc1ccc(C=C(C#N)C(=O)Nc2ccccc2)c2c1CCCC2>>N#CC(=Cc1ccc(O)c2c1CCCC2)C(=O)Nc1ccccc1 -US20130345123A1,1,C=CCCN.O=Cc1ccccc1>>C=CCC/N=C/c1ccccc1 -US05498366,1,CCCCCCCBr.Sc1ccc(Br)cc1>>CCCCCCCSc1ccc(Br)cc1 -US05876984,2,CC(=O)Cl.C[C@H]1CC[C@H]2C(C)(C)[C@@H](N)CC[C@]23Oc2c(c(OCc4ccccc4)cc4c2CN(C(=O)OC(C)(C)C)C4=O)C[C@]13C>>CC(=O)N[C@H]1CC[C@@]23Oc4c(c(OCc5ccccc5)cc5c4CN(C(=O)OC(C)(C)C)C5=O)C[C@]2(C)[C@@H](C)CC[C@H]3C1(C)C -US04925879,7,CCC(O)(CC)CC(=N)C1(c2ccc(Cl)cc2)CCC1>>CCC(O)(CC)CC(N)C1(c2ccc(Cl)cc2)CCC1 -US05972935,1,CN(C)CCN1CCOc2ccc(N)cc21.COC(C=O)OC>>COC(CNc1ccc2c(c1)N(CCN(C)C)CCO2)OC -US20100249229A1,6,CC(C)(C)OC(=O)C[C@]1(CN)C[C@@H]2CC(C3CCCC3)=C[C@@H]21>>NC[C@@]1(CC(=O)O)C[C@@H]2CC(C3CCCC3)=C[C@@H]21 -US20090215725A1,2,CS(=O)(=O)Cl.Nc1ccc(F)cc1I>>CS(=O)(=O)Nc1ccc(F)cc1I -US08546376B2,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(-c5c[nH]nn5)cccc4c3=O)cc2)CCC1>>NC1(c2ccc(-c3c(-c4ccccc4)oc4c(-c5c[nH]nn5)cccc4c3=O)cc2)CCC1 -US20130158075A1,2,COC(=O)C12CC3CC(CC(C(=O)O)(C3)C1)C2.NCC(=O)c1ccc([N+](=O)[O-])cc1>>COC(=O)C12CC3CC(CC(C(=O)NCC(=O)c4ccc([N+](=O)[O-])cc4)(C3)C1)C2 -US20150218160A1,2,CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN[C@H]3C(C)C)cc1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN(S(=O)(=O)c2ccc(C#N)cc2)[C@H]3C(C)C)cc1 -US20120077793A1,3,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1F)C(=O)N1CCC(F)(F)C1.CC(C)OC(=O)N1CCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cn2)CC1>>CC(C)OC(=O)N1CCC(Oc2ccc(-c3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N4CCC(F)(F)C4)c(F)c3)cn2)CC1 -US20140011796A1,1,CC1(C)COCCN1.CC[C@@H](C=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CN1CCOCC1(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US20080242694A1,6,O=C1c2ccccc2C(=O)N1C[C@H](Cc1ccc(Cl)cc1Cl)Nc1nnc(-c2ccc3cnccc3c2)s1>>NC[C@H](Cc1ccc(Cl)cc1Cl)Nc1nnc(-c2ccc3cnccc3c2)s1 -US07572809B2,3,C=C(C)B1OC(C)(C)C(C)(C)O1.COc1cc2cc(Nc3cc(C4CC4)[nH]n3)nc(Cl)c2cc1OC>>C=C(C)c1nc(Nc2cc(C3CC3)[nH]n2)cc2cc(OC)c(OC)cc12 -US20140121198A1,9,N#CC[C@H]1CC[C@H](N=[N+]=[N-])C[C@H]1NC(=O)OCc1ccccc1>>N#CC[C@H]1CC[C@H](N)C[C@H]1NC(=O)OCc1ccccc1 -US20150191478A1,3,O=C1CSC(=S)N1.O=Cc1cc2cncc(C#CC3CC3)c2o1>>O=C1NC(=S)S/C1=C\c1cc2cncc(C#CC3CC3)c2o1 -US20080300242A1,7,CCOc1cc(N2CCN(C3CCN(CCF)CC3)CC2)ccc1[N+](=O)[O-]>>CCOc1cc(N2CCN(C3CCN(CCF)CC3)CC2)ccc1N -US20070015922A1,6,CCC1(CC)c2ccccc2C(CC)(CC)N1Cc1ccccc1>>CCC1(CC)NC(CC)(CC)c2ccccc21 -US08357687B2,3,COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1.OB(O)c1ccccc1OCc1ccccc1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3OCc3ccccc3)[nH]c2c1 -US20070054916A1,3,CNc1ncc2cc(B3OC(C)(C)C(C)(C)O3)ccc2n1.Cc1ccc(C(=O)Nc2cccc(OC(C)C)c2)c(F)c1I>>CNc1ncc2cc(-c3c(C)ccc(C(=O)Nc4cccc(OC(C)C)c4)c3F)ccc2n1 -US06291452B1,2,Nc1c(Cl)cccc1C(=O)c1ccccc1F.O=C(Br)CBr>>O=C(CBr)Nc1c(Cl)cccc1C(=O)c1ccccc1F -US09040693B2,1,CI.O=[N+]([O-])c1ccc(O)cc1F>>COc1ccc([N+](=O)[O-])c(F)c1 -US07807856B2,3,COc1ccc(C=O)cc1.O=C1CCCCC1>>COc1ccc(C=C2CCCCC2=O)cc1 -US07074794B2,1,C1CNCCN1.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1N1CCNCC1 -US20080139572A1,1,CI.COc1cnc(-c2cc[nH]n2)c2[nH]cc(C(=O)C(=O)N3CCN(c4nnnn4-c4ccccn4)CC3)c12>>COc1cnc(-c2ccn(C)n2)c2[nH]cc(C(=O)C(=O)N3CCN(c4nnnn4-c4ccccn4)CC3)c12 -US20020045747A1,2,C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O.NC1Cc2ccccc2N(Cc2ccccc2)C1=O>>C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1Cc2ccccc2N(Cc2ccccc2)C1=O -US07632829B2,1,CC(=O)N1CCN(CCCl)CC1.O=C1CCN(C(=O)/C=C/c2cccc(Cl)c2)CCN1>>CC(=O)N1CCN(CCN2CCN(C(=O)/C=C/c3cccc(Cl)c3)CCC2=O)CC1 -US06225316B1,2,Cc1ccccc1-c1cnccc1C(=O)O.NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ccccc1-c1cnccc1C(=O)NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US04179561,1,COc1ccc(CBr)cc1.O=c1[nH]c2ccccc2c2cc(CO)nn12>>COc1ccc(Cn2c(=O)n3nc(CO)cc3c3ccccc32)cc1 -US06656469B1,6,COC(=O)c1ccc(C#Cc2cncc(C3CCCN3C)c2)cc1>>CN1CCCC1c1cncc(C#Cc2ccc(C(=O)O)cc2)c1 -US07160875B2,2,CC(=O)N1C[C@H](N)C(=O)N(C)c2ccccc21.CC(F)(C(=O)O)C(=O)NCC(F)(F)C(F)(F)F>>CC(=O)N1C[C@H](NC(=O)C(C)(F)C(=O)NCC(F)(F)C(F)(F)F)C(=O)N(C)c2ccccc21 -US08470841B2,2,CC(=O)OC(C)=O.CC(N)C#Cc1ccc(Oc2ccc(OCc3ccccc3)nc2)cc1>>CC(=O)NC(C)C#Cc1ccc(Oc2ccc(OCc3ccccc3)nc2)cc1 -US20090036420A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)Nc3cccc(Cl)c3)cn2)CC1>>O=C(Nc1cccc(Cl)c1)c1ccc(N2CCNCC2)nc1 -US20130331374A1,2,Nc1cc([N+](=O)[O-])ccc1F.O=C(Cl)C1CC1>>O=C(Nc1cc([N+](=O)[O-])ccc1F)C1CC1 -US20130165436A1,8,CCSc1ccc(Br)cn1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)c1ccc(Br)cn1 -US20130345188A1,7,C/C=C1/C(=O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12>>CC[C@H]1C(=O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12 -US08039450B2,6,CCOC(=O)c1ccc(Oc2ccc3c(c2)COB3O)cc1OC>>COc1cc(Oc2ccc3c(c2)COB3O)ccc1C(=O)O -US20060063787A1,1,BrCCc1ccccc1.CC(C)(C)C(=O)OCn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1>>CC(C)(C)C(=O)OCn1c(=O)n(CCc2ccccc2)c(=O)c2c1ncn2Cc1ccccc1 -US20090203674A1,1,C[C@H]1CCC[C@@H](C)N1.Fc1c(Cl)ncnc1Cl>>C[C@H]1CCC[C@@H](C)N1c1ncnc(Cl)c1F -US20040242572A1,7,c1cc(CN2CCCCC2)ccn1>>C1CCN(CC2CCNCC2)CC1 -US20120219593A1,9,CCOC(=O)Cc1c(C)oc2ccc(CN(C)C)cc12.N>>Cc1oc2ccc(CN(C)C)cc2c1CC(N)=O -US07320972B2,3,O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2cccc(Br)c2)N1c1ccc(F)cc1.OB(O)c1ccc(O)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2cccc(-c3ccc(O)cc3)c2)N1c1ccc(F)cc1 -US05721245,2,Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(CN)C4)C(=O)NC2=O)c2ccccc21.O=C(Cl)c1ccccc1>>Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(CNC(=O)c3ccccc3)C4)C(=O)NC2=O)c2ccccc21 -US20070072813A1,6,COc1ccc(Cc2c(O[Si](C)(C)C(C)(C)C)nn(C(C)C)c2C(F)(F)F)c(F)c1>>COc1ccc(Cc2c(O)nn(C(C)C)c2C(F)(F)F)c(F)c1 -US07435815B2,2,CCNCc1cccc(C)n1.Cc1cccc(N(CC(=O)O)S(=O)(=O)c2ncccc2C)c1>>CCN(Cc1cccc(C)n1)C(=O)CN(c1cccc(C)c1)S(=O)(=O)c1ncccc1C -US20020032168A1,1,CC(C)(C)OC(=O)NCCN.O=C1CCCC1>>CC(C)(C)OC(=O)NCCNC1CCCC1 -US20030171413A1,7,O=C(O)CCc1ccc(Cl)c(Cl)c1>>OCCCc1ccc(Cl)c(Cl)c1 -US04183856,2,CN(C)C(=O)Cl.Cc1csc(N)n1>>Cc1csc(NC(=O)N(C)C)n1 -US05681958,2,Nc1ccccc1C(=O)O.O=C(Cl)COc1ccccc1>>O=C(COc1ccccc1)Nc1ccccc1C(=O)O -US08865707B2,1,CC(C)c1ccc(Cl)c(-c2ccc(C(F)(F)F)cc2CBr)c1.COc1ccccc1[C@@H]1CCNC(=O)O1>>COc1ccccc1[C@@H]1CCN(Cc2cc(C(F)(F)F)ccc2-c2cc(C(C)C)ccc2Cl)C(=O)O1 -US08642585B2,6,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(O[C@H]6CCOC6)cc5C)ccc(F)c43)ccc21>>Cc1cc(O[C@H]2CCOC2)cc(C)c1-c1ccc(F)c2c1CC[C@H]2Oc1ccc2c(c1)OC[C@H]2CC(=O)O -US05990122,9,N.O=C1C2C3C=CC(C(=O)O)(C3)C2C(=O)N1Cc1ccccc1>>NC(=O)C12C=CC(C1)C1C(=O)N(Cc3ccccc3)C(=O)C12 -US20120004164A1,6,CCOC(=O)c1sc(N2CCN(CC(=O)c3ccccc3)C2=O)cc1C>>Cc1cc(N2CCN(CC(=O)c3ccccc3)C2=O)sc1C(=O)O -US20040038855A1,1,Cc1ccc(I)cc1.c1ccc2[nH]ccc2c1>>Cc1ccc(-n2ccc3ccccc32)cc1 -US20120142667A1,1,COc1ccc(N)c(C)c1.COc1ccc(Nc2nc(Cl)ncc2Cl)c(NS(C)(=O)=O)c1>>COc1ccc(Nc2ncc(Cl)c(Nc3ccc(OC)cc3NS(C)(=O)=O)n2)c(C)c1 -US20050038072A1,2,COc1ccccc1N=C=S.O=C1CCNCC1C(c1ccccc1)c1ccccc1>>COc1ccccc1NC(=S)N1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1 -US20130079345A1,3,NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1.OB(O)c1ccc(F)cc1C(F)(F)F>>NS(=O)(=O)Cc1cccc(Nc2ncnc(-c3ccc(F)cc3C(F)(F)F)n2)c1 -US20110312941A1,2,Cc1cccc(N2CCC(C(=O)O)CC2)n1.Fc1ccc2c(c1)-c1[nH]c(N3CCOCC3)nc1CCN2>>Cc1cccc(N2CCC(C(=O)N3CCc4nc(N5CCOCC5)[nH]c4-c4cc(F)ccc43)CC2)n1 -US06472413B2,2,NCCc1ccc(-c2ccco2)c(S(N)(=O)=O)c1.O=C(O)/C=C/c1cccs1>>NS(=O)(=O)c1cc(CCNC(=O)/C=C/c2cccs2)ccc1-c1ccco1 -US20130137680A1,7,Nc1c(CN2CCOCC2)cc(Cl)cc1[N+](=O)[O-]>>Nc1cc(Cl)cc(CN2CCOCC2)c1N -US20150259349A1,1,CC(=O)c1cccnc1.CC1C=CC=C2c3ccc(NN)nc3NC21>>C/C(=N/Nc1ccc2c(n1)NC1C2=CC=CC1C)c1cccnc1 -US06660742B2,1,BrCc1ccccc1.Nc1cc(Cl)c([N+](=O)[O-])cc1O>>Nc1cc(Cl)c([N+](=O)[O-])cc1OCc1ccccc1 -US07034039B2,7,CCOC(=O)/C=C/c1ccc2c(=O)n(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c3ccccc3)c2c1>>CCOC(=O)CCc1ccc2c(=O)n(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c3ccccc3)c2c1 -US20130296329A1,6,COCc1cccc2c1CN(C(=O)OC(C)(C)C)C2>>COCc1cccc2c1CNC2 -US05541286,6,COC(=O)C=Cc1cccc(CNC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)NCc1cccc(C=CC(=O)O)c1 -US03932508,9,CC(C)(C)C(=O)CSC(F)F.NO>>CC(C)(C)C(CSC(F)F)=NO -US20060148801A1,9,COc1ccc2c(C(=O)O)n[nH]c2c1>>COc1ccc2c(C=O)n[nH]c2c1 -US06825354B2,1,CCOC(=O)C(Br)c1cccc2ccccc12.Oc1ccc(S)cc1>>CCOC(=O)C(Sc1ccc(O)cc1)c1cccc2ccccc12 -US20080176883A1,6,CC(C)(C)OC(=O)N1CCC(N2CCC(c3ccccc3)CC2)C1>>c1ccc(C2CCN(C3CCNC3)CC2)cc1 -US20120328569A1,7,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc([N+](=O)[O-])c(-c4nc5c(F)cccc5o4)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc(N)c(-c4nc5c(F)cccc5o4)c3)cc12 -US20140038957A1,2,COCC1CN(C(=O)OC(C)(C)C)CCC1N.O=C(Cl)c1ccccc1>>COCC1CN(C(=O)OC(C)(C)C)CCC1NC(=O)c1ccccc1 -US20100292210A1,1,COc1cc([N+](=O)[O-])ccc1F.Cc1nc[nH]n1>>COc1cc([N+](=O)[O-])ccc1-n1cnc(C)n1 -US20130225591A1,9,N#C[Cu].O=C(Cc1ccc2ccccc2c1)Nc1ncn2c(Br)csc12>>N#Cc1csc2c(NC(=O)Cc3ccc4ccccc4c3)ncn12 -US08008298B2,3,CC(C)(C)C(=O)c1c[nH]c2ncc(Br)nc12.OB(O)c1ccccc1O>>CC(C)(C)C(=O)c1c[nH]c2ncc(-c3ccccc3O)nc12 -US05840749,1,CNO.CS(=O)(=O)OCCc1ccc2c(c1)C(=O)c1ccccc1CO2>>CN(O)CCc1ccc2c(c1)C(=O)c1ccccc1CO2 -US20090143385A1,2,COC(=O)CC(=O)Cl.Cc1onc(-c2ccccc2)c1COc1ccc(N)nn1>>COC(=O)CC(=O)Nc1ccc(OCc2c(-c3ccccc3)noc2C)nn1 -US08901141B2,2,COC(=O)c1ccc(Cl)c(N)c1NCCCO.COc1cc(C)c(N=C=S)cn1>>COC(=O)c1ccc(Cl)c(NC(=S)Nc2cnc(OC)cc2C)c1NCCCO -US07858776B2,1,BrCC1CC1.COc1ccc2c(c1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1)[C@@H](c1ccccc1)O2>>COc1ccc2c(c1)N(CC1CC1)C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1)[C@@H](c1ccccc1)O2 -US08193230B2,2,C1CCNC1.COC(=O)c1cc2c(ncn2CCC(=O)O)c(F)c1Nc1ccc(Br)cc1Cl>>COC(=O)c1cc2c(ncn2CCC(=O)N2CCCC2)c(F)c1Nc1ccc(Br)cc1Cl -US20110257151A1,6,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cc(F)ccc1C)N2>>Cc1ccc(F)cc1C1Nc2ccc(C(=O)O)cc2CC1(C)C -US04734419,2,NCc1ccc(I)cc1F.O=C(O)c1ccc(Br)cc1[N+](=O)[O-]>>O=C(NCc1ccc(I)cc1F)c1ccc(Br)cc1[N+](=O)[O-] -US06762180B1,2,COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN)cc1)c1ccccc1.CS(=O)(=O)Cl>>COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CNS(C)(=O)=O)cc1)c1ccccc1 -US04448908,2,C=C(C)C(=O)Cl.CCCCCOC(CN)OCCCCC>>C=C(C)C(=O)NCC(OCCCCC)OCCCCC -US20060004003A1,1,CC(C)(C)OC(=O)CBr.CCn1ncc2c(-c3cncc(C)c3)c(CO)c(COC)nc21>>CCn1ncc2c(-c3cncc(C)c3)c(COCC(=O)OC(C)(C)C)c(COC)nc21 -US20080103132A1,6,COc1ccc(-c2cn(Cc3ccccc3)c3c2CN(C(=O)OC(C)(C)C)CC3)cc1>>COc1ccc(-c2cn(Cc3ccccc3)c3c2CNCC3)cc1 -US20080194549A1,1,CN.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C=O)C(C)C)ccc1OC>>CNC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C -US07989438B2,6,CNCCOCC1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)N(C)CC(OC)OC)cc3n2C1>>CNCCOCC1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)N(C)CC=O)cc3n2C1 -US06440956B1,2,Nc1ccc(C(=O)O)cc1.O=C(O)c1ccc([N+](=O)[O-])cc1>>O=C(O)c1ccc(NC(=O)c2ccc([N+](=O)[O-])cc2)cc1 -US20060247227A1,1,C1CC(N2CCC(OC3CCNCC3)CC2)C1.CCC(=O)c1ccc(F)cc1>>CCC(=O)c1ccc(N2CCC(OC3CCN(C4CCC4)CC3)CC2)cc1 -US04927926,1,CC1(NC(=O)C(F)(F)F)CNC1.O=C(O)c1cn(-c2ccc(F)cc2)c2c(F)c(F)c(F)cc2c1=O>>CC1(NC(=O)C(F)(F)F)CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4)c3c2F)C1 -US20100317663A1,1,CNC(=O)c1ccccc1Nc1cc(Cl)ncc1Br.COc1cc(N2CCOCC2)ccc1N>>CNC(=O)c1ccccc1Nc1cc(Nc2ccc(N3CCOCC3)cc2OC)ncc1Br -US08470816B2,6,CN(C(=O)c1ccc(N2CCOCC2)cc1)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(Cl)c(Cl)c1>>CN(C(=O)c1ccc(N2CCOCC2)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1 -US07635695B2,1,COc1ccc(CNc2ncc(C#N)c3sc(I)cc23)cc1.c1c[nH]cn1>>COc1ccc(CNc2ncc(C#N)c3sc(-n4ccnc4)cc23)cc1 -US20090124600A1,1,CC(C)(C)OC(=O)NC1CCNCC1.O=C(CBr)c1ccccc1>>CC(C)(C)OC(=O)NC1CCN(CC(=O)c2ccccc2)CC1 -US04271163,2,CC(=O)Cl.Nc1cccc(C2=NNC(=O)C3CC23)c1>>CC(=O)Nc1cccc(C2=NNC(=O)C3CC23)c1 -US09040714B2,2,CN1CCNCC1.O=Cc1c(O)ccc2nc(-c3ccc(C(=O)O)cc3)[nH]c12>>CN1CCN(C(=O)c2ccc(-c3nc4ccc(O)c(C=O)c4[nH]3)cc2)CC1 -US20050107410A1,2,Cc1ccc2c(OCCN3CCC(Cc4cccc(N)c4)CC3)cccc2n1.O=C(Cl)CCl>>Cc1ccc2c(OCCN3CCC(Cc4cccc(NC(=O)CCl)c4)CC3)cccc2n1 -US08143274B2,6,O=C(COCc1ccccc1)Nc1ccc2cc(-c3ccccc3)[nH]c(=O)c2c1>>O=C(CO)Nc1ccc2cc(-c3ccccc3)[nH]c(=O)c2c1 -US20040249211A1,6,COc1ccc(C)cc1C(CCN(C(C)C)C(C)C)c1ccccc1>>Cc1ccc(O)c(C(CCN(C(C)C)C(C)C)c2ccccc2)c1 -US20120101100A1,4,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(C(=O)NNC(=O)C(C)(C)OC(C)=O)c2)cn1>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(-c3nnc(C(C)(C)OC(C)=O)o3)c2)cn1 -US04291034,1,CN(C)CCCN.O=C1CC(c2ccc(Cl)c(Cl)c2)Cc2c1c(=O)c1cc(Cl)ccc1n2O>>CN(C)CCCN=C1CC(c2ccc(Cl)c(Cl)c2)Cc2c1c(=O)c1cc(Cl)ccc1n2O -US20080200535A1,1,CC(C)O.O=C(O)c1ccc(F)c(C(F)(F)F)c1>>CC(C)Oc1ccc(C(=O)O)cc1C(F)(F)F -US07482452B2,1,Cc1cccc(I)c1.N#Cc1sc2c(ccc(=O)n2-c2ccccc2)c1N>>Cc1cccc(Nc2c(C#N)sc3c2ccc(=O)n3-c2ccccc2)c1 -US07790737B2,1,CCNCC1CCCC1.Cc1nn(C)c2nc(Cl)c(C=O)cc12>>CCN(CC1CCCC1)c1nc2c(cc1C=O)c(C)nn2C -US06410530B1,2,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.O=C(O)c1cccc(Oc2ccccc2)c1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2cccc(Oc4ccccc4)c2)CC3)CC1 -US20090264428A1,2,CCc1cccc(-c2c(Cl)cccc2[C@](O)(CCCN)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1.O=C(O)CO>>CCc1cccc(-c2c(Cl)cccc2[C@](O)(CCCNC(=O)CO)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1 -US20120095011A1,9,COc1cccc(C=O)c1.NO>>COc1cccc(C=NO)c1 -US06211184B1,2,C#C[C@@H](N)CC(=O)OCC.O=C(O)Cn1c(C2CC2)ccc(NCc2ccc3c(n2)NCCC3)c1=O>>C#C[C@H](CC(=O)OCC)NC(=O)Cn1c(C2CC2)ccc(NCc2ccc3c(n2)NCCC3)c1=O -US04898455,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(-c2ccc(Br)cc2)nc1>>COC=Cc1ccc(-c2ccc(Br)cc2)nc1 -US09040522B2,2,CNCCCOC.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>COCCCN(C)C(=O)c1ccc(-n2ncc(-c3ccc(C#N)cc3C)c2O)nc1 -US04851526,1,CCCCCC(=O)CC.NCCOc1ccc(-n2ccnc2)cc1>>CCCCCC(CC)NCCOc1ccc(-n2ccnc2)cc1 -US20040063698A1,6,CCOC(=O)C(C)(C)C(=O)c1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(C)(C)C(=O)c1ccc(O)cc1 -US05202437,1,CO.CS(=O)(=O)O[C@H]1CN[C@H](C(=O)N2CCNC2=O)C1>>CN1C[C@H](OS(C)(=O)=O)C[C@H]1C(=O)N1CCNC1=O -US20140296201A1,7,CC(C)(C)OC(=O)N1CCC(F)(F)CC1C#N>>CC(C)(C)OC(=O)N1CCC(F)(F)CC1CN -US05026913,1,CC(C)(S)CNc1ccccc1N.CC(C)SC(C)(C)C=O>>CC(C)SC(C)(C)CNc1ccccc1NCC(C)(C)S -US20110166163A1,3,COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3)c(-c3ccc(C=O)cn3)c12.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=Cc1ccc(-c2c(-c3ccccc3)oc3ncnc(NCCCCCC(=O)OC)c23)nc1 -US08222281B2,1,CCOC(=O)CC(OCC)c1ccc(O)cc1.OCc1cccc(OC(F)(F)F)c1>>CCOC(=O)CC(OCC)c1ccc(OCc2cccc(OC(F)(F)F)c2)cc1 -US08026257B2,6,CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(C(F)(F)F)cc2c1NC(=O)C2>>CC(OCC1(c2ccc(F)cc2)CCNCC1)c1cc(C(F)(F)F)cc2c1NC(=O)C2 -US08378124B2,2,CCC[C@H](N[S@@](=O)C(C)(C)C)C1(C(=O)OCC)SCCS1.CN>>CCC[C@H](N[S@@](=O)C(C)(C)C)C1(C(=O)NC)SCCS1 -US20140171422A1,1,CCI.O=c1[nH]ccc2c(Br)cccc12>>CCn1ccc2c(Br)cccc2c1=O -US20150065522A1,2,CCOC(=O)C(=O)Cl.CCc1c(C)[nH]c2c(C(=O)NN)cnn2c1=O>>CCOC(=O)C(=O)NNC(=O)c1cnn2c(=O)c(CC)c(C)[nH]c12 -US04528287,1,CC(C)=O.Nc1ccc(F)c(F)c1F>>CC(C)Nc1ccc(F)c(F)c1F -US20090281141A1,2,COc1ccc2c(OC3CC4C(=O)NC5(C(=O)O)CC5C=CCCCCN(C)C(=O)C4C3)nc(-c3nc(C4CC4)cs3)cc2c1.NS(=O)(=O)C1CC1>>COc1ccc2c(OC3CC4C(=O)NC5(C(=O)NS(=O)(=O)C6CC6)CC5C=CCCCCN(C)C(=O)C4C3)nc(-c3nc(C4CC4)cs3)cc2c1 -US07754718B2,6,O=C(OCc1ccccc1)c1cc2ccc3c(c2c(-c2ccc4c(c2)OCO4)c1COCc1ccccc1)OCO3>>O=C(O)c1cc2ccc3c(c2c(-c2ccc4c(c2)OCO4)c1COCc1ccccc1)OCO3 -US20110071194A1,1,CCc1cccc([C@@H](O)[C@H](C)N)c1.Fc1ccc(-n2ncc3cc(I)ccc32)cc1>>CCc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)N)c1 -US20100048551A1,1,CCCCN.Fc1ccc2[nH]c3c(Br)cnc(Cl)c3c2c1>>CCCCNc1ncc(Br)c2[nH]c3ccc(F)cc3c12 -US06833378B2,1,CCC(CC)Nc1cc(C)nc(Cl)c1C(N)=O.Cc1cc(Br)cc(C)c1O>>CCC(CC)Nc1cc(C)nc(Oc2c(C)cc(Br)cc2C)c1C(N)=O -US20110166121A1,9,CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(N3CCC(=O)C3)nc2s1.NO>>CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(N3CCC(=NO)C3)nc2s1 -US20080312286A1,6,COC(=O)CCc1ccc(OCCCCOc2cc3c(c(Cl)c2Cl)C(=O)C(C)(C2CCCC2)C3)cc1>>CC1(C2CCCC2)Cc2cc(OCCCCOc3ccc(CCC(=O)O)cc3)c(Cl)c(Cl)c2C1=O -US20070213348A1,6,CC(C)(C)OC(=O)/C=C/c1ccc(C(=C2CCCCCC2)c2cccc(O)c2)cc1>>O=C(O)/C=C/c1ccc(C(=C2CCCCCC2)c2cccc(O)c2)cc1 -US20090163508A1,6,CC(C)(C)OC(=O)N1CCN(c2nccc(-c3ccccc3)n2)CC1>>c1ccc(-c2ccnc(N3CCNCC3)n2)cc1 -US06951868B2,3,CC(=O)Cl.c1ccc2c(c1)CCCO2>>CC(=O)c1ccc2c(c1)CCCO2 -US08518934B2,1,CCOC(=O)C(=O)Cl.NOC1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1>>CCOC(=O)C(=O)NOC1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1 -US04604397,6,COc1ccc2c(c1)[C@H]1CCCN(Cc3ccccc3)[C@@H]1CO2>>COc1ccc2c(c1)C1CCCNC1CO2 -US08940724B2,1,Cc1c(-c2ccc(N3CCN(C)CC3)nc2)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>Cc1c(-c2ccc(N3CCN(C)CC3)nc2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1 -US06455587B1,2,CC(C)CN([C@@H](CCCCN)C(=O)O)S(=O)(=O)c1ccc([N+](=O)[O-])cc1.COc1ccc(OC)c(C=CC(=O)O)c1>>COc1ccc(OC)c(C=CC(=O)NCCCC[C@@H](C(=O)O)N(CC(C)C)S(=O)(=O)c2ccc([N+](=O)[O-])cc2)c1 -US20080255124A1,1,CC(C)(C)CN(CCO)c1ccc(C#N)c(C(F)(F)F)c1.NS(=O)(=O)c1ccc(O)cc1>>CC(C)(C)CN(CCOc1ccc(S(N)(=O)=O)cc1)c1ccc(C#N)c(C(F)(F)F)c1 -US06727245B2,1,Nc1cccc([N+](=O)[O-])c1.Nc1cccnc1Cl>>Nc1cccnc1Nc1cccc([N+](=O)[O-])c1 -US06936608B2,3,Brc1cnc2nccnn12.CC1(C)OB(c2ccc(F)c(-c3ccccc3C#N)c2)OC1(C)C>>N#Cc1ccccc1-c1cc(-c2cnc3nccnn23)ccc1F -US04333730,6,CC(=O)Nc1cc([N+](=O)[O-])ccc1OCCCN1C(=O)c2ccccc2C1=O>>CC(=O)Nc1cc([N+](=O)[O-])ccc1OCCCN -US20140128390A1,7,Cc1nn(C)cc1-c1cc2ncnc(C3=CCNCC3)c2s1>>Cc1nn(C)cc1-c1cc2ncnc(C3CCNCC3)c2s1 -US07544676B2,1,CC1(C)C(NC(=O)c2ccc(Br)c(S(=O)(=O)N3CCCC3)c2)[C@@]2(C)CC[C@@H]1C2.NCc1ccccc1>>CC1(C)C(NC(=O)c2ccc(NCc3ccccc3)c(S(=O)(=O)N3CCCC3)c2)[C@@]2(C)CC[C@@H]1C2 -US09156827B2,6,COc1ccc2c(c1C1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O>>COc1ccc2c(c1C1CCNCC1)O/C(=C\c1n[nH]c3ccccc13)C2=O -US20110144081A1,2,CN(C(=O)Oc1ccc(F)cc1)[C@@H]1CN(C(=O)C2CCNC2)C[C@H]1c1ccc(Cl)cc1.O=C(Cl)C1CC1>>CN(C(=O)Oc1ccc(F)cc1)[C@@H]1CN(C(=O)C2CCN(C(=O)C3CC3)C2)C[C@H]1c1ccc(Cl)cc1 -US06162791,1,COc1nsc(Cl)n1.NCC(N)=O>>COc1nsc(NCC(N)=O)n1 -US06858651B2,1,BrCCCCCCBr.CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](O)CC1>>CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](OCCCCCCBr)CC1 -US05563142,1,CCCNc1cccnc1N1CCNCC1.COc1c(C)cc(CCl)cc1C>>CCCNc1cccnc1N1CCN(Cc2cc(C)c(OC)c(C)c2)CC1 -US20070213337A1,1,CC(C)(C)OC(=O)N1CCN2C(=O)c3c(cc(Br)cc3C(F)(F)F)[C@@H]2C1.C[S-]>>CSc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCN(C(=O)OC(C)(C)C)C[C@@H]21 -US20050065164A1,1,CCC1(C)CN(Cc2ccccc2)CC(C)C1=O.[NH4+]>>CCC1(C)CN(Cc2ccccc2)CC(C)C1N -US20040132716A1,2,CCN1CCN(C2CCNCC2)CC1.Cc1ccc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)O)cc1C>>CCN1CCN(C2CCN(C(=O)C(CC(=O)N3CCC(N4Cc5ccccc5NC4=O)CC3)Cc3ccc(C)c(C)c3)CC2)CC1 -US06924292B2,2,CC1(C)Cc2cc(N)c3c(c2C(c2ccccc2)=N1)CC(C)(C)O3.CS(=O)(=O)Cl>>CC1(C)Cc2cc(NS(C)(=O)=O)c3c(c2C(c2ccccc2)=N1)CC(C)(C)O3 -US20090149468A1,2,CCO.O=C(O)c1ccnc(Cl)c1>>CCOC(=O)c1ccnc(Cl)c1 -US07786109B2,1,CC(C)(C)[Si](C)(C)OCCBr.CC(C)N1CCC(Oc2ccc3c(c2)cc2n3[C@H](C)CNC2=O)CC1>>CC(C)N1CCC(Oc2ccc3c(c2)cc2n3[C@H](C)CN(CCO[Si](C)(C)C(C)(C)C)C2=O)CC1 -US04267359,1,CC(C)C(C=Cc1ccccc1)C(=O)O.O=C(c1ccccc1)c1cccc(CBr)c1>>CC(C)C(C=Cc1ccccc1)C(=O)OCc1cccc(C(=O)c2ccccc2)c1 -US20050165058A1,1,CI.COC(=O)c1cc(O)c(Cl)c(O)c1>>COC(=O)c1cc(O)c(Cl)c(OC)c1 -US05403851,2,NCCc1ccc(F)cc1.O=C(Cl)OCc1ccccc1>>O=C(NCCc1ccc(F)cc1)OCc1ccccc1 -US20090181946A1,3,C=CN1C(=O)CCCc2c(F)c(F)cc(F)c21.ICI>>O=C1CCCc2c(F)c(F)cc(F)c2N1C1CC1 -US06211215B1,1,CS(=O)(=O)OCCCc1ccccc1OCc1coc(/C=C/c2ccccc2)n1.c1c[nH]cn1>>C(=C/c1nc(COc2ccccc2CCCn2ccnc2)co1)\c1ccccc1 -US20050222261A1,2,CC(=O)O.NCc1ccc(C(F)(F)F)cc1>>CC(=O)NCc1ccc(C(F)(F)F)cc1 -US06110956,1,NCc1ccccc1.O=C1CCC(c2c[nH]c3ccc(F)cc23)CC1>>Fc1ccc2[nH]cc([C@@H]3CC[C@@H](NCc4ccccc4)CC3)c2c1 -US20150152068A1,1,Clc1cccc(I)c1.O=c1[nH]ccc2cc(C3CC3)cc(F)c12>>O=c1c2c(F)cc(C3CC3)cc2ccn1-c1cccc(Cl)c1 -US09120794B2,3,CON(C)C(=O)CCc1ccc(Cl)c(Cl)c1.C[Mg+]>>CC(=O)CCc1ccc(Cl)c(Cl)c1 -US08034812B2,2,Cn1cc(C(=O)O)nn1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>Cn1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)nn1 -US05753679,6,Cc1ccc(C(=O)OC2CCN(Cc3ccccc3)CC2)c(NC(=O)C(F)(F)F)c1>>Cc1ccc(C(=O)OC2CCN(Cc3ccccc3)CC2)c(N)c1 -US07550478B2,6,COc1ccc2ccc3ncc(Cl)cc3c(=O)c2c1F>>O=c1c2cc(Cl)cnc2ccc2ccc(O)c(F)c12 -US20040006081A1,2,O=C(Br)CBr.c1ccc(Nc2ccccc2)cc1>>O=C(CBr)N(c1ccccc1)c1ccccc1 -US20080255105A1,2,COc1ccc(C(=O)O)cc1Br.Cc1cc(N2CCOCC2)ccc1N>>COc1ccc(C(=O)Nc2ccc(N3CCOCC3)cc2C)cc1Br -US20040259912A1,7,O=C(c1ccccc1)c1cccc(Cl)c1>>OC(c1ccccc1)c1cccc(Cl)c1 -US08063099B2,2,Cc1c(C(=O)O)c2ccccc2n1C.Cc1nc(C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c(-c2cccc(Cl)c2)s1>>Cc1nc(C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2c(C)n(C)c3ccccc23)c(-c2cccc(Cl)c2)s1 -US20080096861A1,6,CN(CC(=O)OCc1ccccc1)C1CCCc2cccnc21>>CN(CC(=O)O)C1CCCc2cccnc21 -US20130116243A1,6,CN1Cc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc2N(C)C1=O>>CN1Cc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)cc2N(C)C1=O -US04647560,6,CC1=NC2(CCN(C(=O)OCc3ccccc3)CC2)C(=O)Nc2ccccc21>>CC1=NC2(CCNCC2)C(=O)Nc2ccccc21 -US07572801B2,2,N=C(N)CCCCc1ccc(F)cc1.O=C(O)c1cc(Cl)cnc1Cl>>N=C(CCCCc1ccc(F)cc1)NC(=O)c1cc(Cl)cnc1Cl -US20150239908A1,7,CC(C)=C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1>>CC(C)C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1 -US20090215857A1,3,CC(C)(C)OC(=O)N1CC[C@H](OCc2c(Cl)cccc2C#N)C1.OB(O)c1cc(F)ccc1F>>CC(C)(C)OC(=O)N1CC[C@H](OCc2c(C#N)cccc2-c2cc(F)ccc2F)C1 -US20100029657A1,3,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.CCOC(=O)N1C2CCC1CC(c1ccnc3c(I)c(-c4ccncc4)nn13)C2>>CCOC(=O)N1C2CCC1CC(c1ccnc3c(-c4cccc5[nH]ccc45)c(-c4ccncc4)nn13)C2 -US20110028509A1,2,N#Cc1ccc(CNCc2ccc(F)cc2F)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>N#Cc1ccc(CN(Cc2ccc(F)cc2F)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20120149718A1,6,CCOC(=O)c1ccc(C(Cc2ccc(F)cc2)C(=O)Nc2nc3ccccc3o2)cc1>>O=C(O)c1ccc(C(Cc2ccc(F)cc2)C(=O)Nc2nc3ccccc3o2)cc1 -US07968570B2,1,CO.O=C1c2ccc(Br)cc2CN1Cc1ccccc1>>COc1ccc2c(c1)CN(Cc1ccccc1)C2=O -US05981559,1,CC(C)(C)c1csc(COc2cccc(C(=O)Nc3cc(CCCS(=O)(=O)c4ccc(Cl)cc4)ccc3O)c2)n1.N#CCBr>>CC(C)(C)c1csc(COc2cccc(C(=O)Nc3cc(CCCS(=O)(=O)c4ccc(Cl)cc4)ccc3OCC#N)c2)n1 -US20130072494A1,2,Nc1scc(Br)c1-c1ncn[nH]1.O=C(O)CN1C(=O)CCc2cnccc21>>O=C(CN1C(=O)CCc2cnccc21)Nc1scc(Br)c1-c1ncn[nH]1 -US08546376B2,1,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(Br)cccc4c3=O)cc2)CCC1.O=C1CNCCN1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(N5CCNC(=O)C5)cccc4c3=O)cc2)CCC1 -US05116869,4,COC(=O)CCCCCC(O)C1C(=O)C=CC1C=CC(CCCCCO[SiH](C)C)C(C)(C)C.OO>>COC(=O)CCCCCC(O)C1C(=O)C2OC2C1C=CC(CCCCCO[SiH](C)C)C(C)(C)C -US07632829B2,1,CI.COc1ccc(COc2ccc(C)nc2CO)cc1>>COCc1nc(C)ccc1OCc1ccc(OC)cc1 -US20150266812A1,2,CN1CCCNCC1.O=C(O)Cn1nc(-c2ccccc2)c2c(Cl)c(-c3ccccc3)nnc21>>CN1CCCN(C(=O)Cn2nc(-c3ccccc3)c3c(Cl)c(-c4ccccc4)nnc32)CC1 -US05650428,2,COC(=O)CCCCNC(=O)C(CO)NS(=O)(=O)c1ccc(Cl)cc1.CS(=O)(=O)Cl>>COC(=O)CCCCNC(=O)C(COS(C)(=O)=O)NS(=O)(=O)c1ccc(Cl)cc1 -US20100311966A1,2,CCOC(=O)c1sc(N2CC[C@H](N)C2)nc1C.CCc1[nH]c(C(=O)O)nc1Cl>>CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)C2)nc1C -US08354444B2,1,CC(C)(C)CC1NC(C(=O)Nc2ccc(C(=O)CBr)cc2)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.CNC>>CN(C)CC(=O)c1ccc(NC(=O)C2NC(CC(C)(C)C)C(C#N)(c3ccc(Cl)cc3F)C2c2cccc(Cl)c2F)cc1 -US20150152108A1,3,O=S1(=O)c2ccc(Cl)nc2N[C@H]2CCN1C2.OB(O)c1cccc(C(F)(F)F)c1>>O=S1(=O)c2ccc(-c3cccc(C(F)(F)F)c3)nc2N[C@H]2CCN1C2 -US08124629B2,9,CCS(=O)(=O)c1ccc(CO)cc1.ClC(Cl)(Cl)Cl>>CCS(=O)(=O)c1ccc(CCl)cc1 -US08115005B2,1,ClCCN1CCCCC1.Oc1ccc(-n2nccc2C(F)(F)F)cc1>>FC(F)(F)c1ccnn1-c1ccc(OCCN2CCCCC2)cc1 -US07368458B2,7,COC(=O)/C(=C/c1cc(-c2ccccc2)cnc1NC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>COC(=O)C(Cc1cc(-c2ccccc2)cnc1NC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1 -US20090226398A1,3,CCCCB(O)O.Fc1cccc(-c2nc3cnn(Cc4ccc(-c5ccc(Br)c(C(F)(F)F)c5)nc4)cc-3n2)c1F>>CCCCc1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)cn2)cc1C(F)(F)F -US20140121246A1,7,CCOC(=O)C=C1CCCc2cc(OC)ccc21>>CCOC(=O)CC1CCCc2cc(OC)ccc21 -US20080004309A1,7,C=C(C)Cc1nc(C(=O)OCC)c(O)c2sc(-c3ccccc3)nc12>>CCOC(=O)c1nc(CC(C)C)c2nc(-c3ccccc3)sc2c1O -US20070082912A1,4,CC(=O)CCC(=O)c1cc(Br)ccc1OCc1ccc(F)cc1.COC(=O)c1cc(N)ccc1NC(C)=O>>COC(=O)c1cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2)ccc1NC(C)=O -US08541457B2,1,Cc1nc(NC(=O)c2cc[nH]c(=O)c2)sc1C(=O)NCc1ccccc1.Ic1ccccc1>>Cc1nc(NC(=O)c2ccn(-c3ccccc3)c(=O)c2)sc1C(=O)NCc1ccccc1 -US20110130398A1,6,CC(=O)OCC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12>>CC(=O)OCC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12 -US20150210727A1,7,O=[N+]([O-])c1ccc2[nH]c(-c3ccncc3)nc2c1>>Nc1ccc2[nH]c(-c3ccncc3)nc2c1 -US20150190457A1,2,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)O.N[C@H](C(=O)O)C12CC(C(F)(F)F)(C1)C2>>CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)N[C@H](C(=O)O)C12CC(C(F)(F)F)(C1)C2 -US20040106604A1,6,COC(=O)c1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)ccnc2c1>>O=C(O)c1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)ccnc2c1 -US20080103183A1,1,BrCC1CC1.CC(C)c1cn(C2C3CC4CC(C3)CC2C4)c(=O)[nH]1>>CC(C)c1cn(C2C3CC4CC(C3)CC2C4)c(=O)n1CC1CC1 -US07429585B2,2,CC(C)COc1ccc(S(C)(=O)=O)cc1C(=O)O.CCS(=O)(=O)c1ccc2oc(N3CCNCC3)nc2c1>>CCS(=O)(=O)c1ccc2oc(N3CCN(C(=O)c4cc(S(C)(=O)=O)ccc4OCC(C)C)CC3)nc2c1 -US08957089B2,2,CCCCS(=O)(=O)NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2.CCN=C=O>>CCCCS(=O)(=O)NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)N(C(=O)NCC)CC2 -US20140128385A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(N)(CO)c1cc(Br)ccc1F>>CC(C)(C)OC(=O)NC(C)(CO)c1cc(Br)ccc1F -US20150239919A1,6,CC(=O)c1cn(CC(=O)OC(C)(C)C)c2ccc(OCc3ccccc3)cc12>>CC(=O)c1cn(CC(=O)OC(C)(C)C)c2ccc(O)cc12 -US20120077979A1,9,[N-]=[N+]=NCC1CC(c2nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c3c(N)nccn23)C1>>NC[C@@H]1C[C@H](c2nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c3c(N)nccn23)C1 -US08999957B2,2,N#Cc1ccccc1CN1CCC[C@@H](N)C1.O=C(O)c1ccc2c(c1)c(-c1ccncc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>N#Cc1ccccc1CN1CCC[C@@H](NC(=O)c2ccc3c(c2)c(-c2ccncc2)nn3C(c2ccccc2)(c2ccccc2)c2ccccc2)C1 -US08569317B2,8,CSCCOc1cccc(C=O)c1.OO>>CS(=O)CCOc1cccc(C=O)c1 -US08748426B2,2,COC(=O)C1CCCC(N2Cc3ccc(-c4ccc(N)cc4)cc3C2=O)C1.O=C(Cl)c1cccc(Cl)c1>>COC(=O)C1CCCC(N2Cc3ccc(-c4ccc(NC(=O)c5cccc(Cl)c5)cc4)cc3C2=O)C1 -US08404731B2,3,O=C1CN(c2ccc(-c3nc(-c4ccc(Cl)cc4Cl)cn3Cc3ccc(Br)cc3)cc2)S(=O)(=O)N1.OB(O)c1ccc(C2CCCCC2)cc1>>O=C1CN(c2ccc(-c3nc(-c4ccc(Cl)cc4Cl)cn3Cc3ccc(-c4ccc(C5CCCCC5)cc4)cc3)cc2)S(=O)(=O)N1 -US05075433,6,COC(=O)CCCCCCCCCCCO[C@@H]1O[C@H](C(=O)OC)[C@@H](OC(C)=O)[C@H](OCc2ccccc2)[C@H]1OC(C)=O>>COC(=O)CCCCCCCCCCCO[C@@H]1O[C@H](C(=O)OC)[C@@H](OC(C)=O)[C@H](O)[C@H]1OC(C)=O -US20120316147A1,2,CC(C)(N)c1nccs1.O=C(O)c1ccc(C2CCCC2)c(-c2cccc(Cl)c2)n1>>CC(C)(NC(=O)c1ccc(C2CCCC2)c(-c2cccc(Cl)c2)n1)c1nccs1 -US20040127492A1,3,COC(=O)c1c2c(nn1CCCNC(=O)OC(C)(C)C)-c1cc(Br)c(OC)cc1CC2.O=[N+]([O-])c1cccc(B(O)O)c1>>COC(=O)c1c2c(nn1CCCNC(=O)OC(C)(C)C)-c1cc(-c3cccc([N+](=O)[O-])c3)c(OC)cc1CC2 -US20090186876A1,2,CCOC(=O)c1cnc(N2CCNCC2)c(Cl)c1.O=C=Nc1cccc2ccccc12>>CCOC(=O)c1cnc(N2CCN(C(=O)Nc3cccc4ccccc34)CC2)c(Cl)c1 -US09040522B2,2,CN(CC(F)F)[C@H]1CCCNC1.Cc1c(-c2cnn(-c3ccc(C(=O)O)cn3)c2O)ccc(C#N)c1F>>Cc1c(-c2cnn(-c3ccc(C(=O)N4CCC[C@H](N(C)CC(F)F)C4)cn3)c2O)ccc(C#N)c1F -US05677464,1,C[C@@H](n1ccn(-c2ccc(OCC(F)(F)C(F)F)cc2)c1=O)[C@](O)(COS(C)(=O)=O)c1ccccc1F.c1nc[nH]n1>>C[C@@H](n1ccn(-c2ccc(OCC(F)(F)C(F)F)cc2)c1=O)[C@@](O)(Cn1cncn1)c1ccccc1F -US20070072897A1,7,OC[C@@H](O)[C@H](c1ccccc1)n1ccc2cc(C#Cc3ccccc3)ccc21>>OC[C@@H](O)[C@H](c1ccccc1)n1ccc2cc(CCc3ccccc3)ccc21 -US20140316089A1,3,CC(C)c1cccc(C(C)C)c1NC(C)(C)c1cccc(Br)n1.Cc1cc(C)c(NCc2ccc3ccccc3c2B2OC(C)(C)C(C)(C)O2)c(C)c1>>Cc1cc(C)c(NCc2ccc3ccccc3c2-c2cccc(C(C)(C)Nc3c(C(C)C)cccc3C(C)C)n2)c(C)c1 -US06645980B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1CCCNC1>>CC(C)(C)OC(=O)N1CCCC(CO)C1 -US05739351,2,COc1ccccc1[C@]1(O)C[C@H](CC#N)C[C@H]2CNC[C@H]21.O=C(O)Cc1ccccc1OCc1ccccc1>>COc1ccccc1[C@]1(O)C[C@H](CC#N)C[C@H]2CN(C(=O)Cc3ccccc3OCc3ccccc3)C[C@H]21 -US20150031541A1,4,CSC1CN(C(=O)Cn2nc(C(F)(F)F)cc2C)CCC1C(N)=S.O=C(CCl)C1=NOC(c2c(F)cccc2F)C1>>CSC1CN(C(=O)Cn2nc(C(F)(F)F)cc2C)CCC1c1nc(C2=NOC(c3c(F)cccc3F)C2)cs1 -US20120316147A1,2,COC(=O)C(C)(C)N.O=C(O)c1ccc(C2CC2)c(Nc2ccc(Cl)cc2Cl)n1>>COC(=O)C(C)(C)NC(=O)c1ccc(C2CC2)c(Nc2ccc(Cl)cc2Cl)n1 -US08143271B2,6,O=C(c1c(F)ccc(OCc2ccccc2)c1F)c1c[nH]c2ncccc12>>O=C(c1c(F)ccc(O)c1F)c1c[nH]c2ncccc12 -US08252935B2,1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCNC2)c1.FC(F)(F)c1ccc(I)cc1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(c3ccc(C(F)(F)F)cc3)C2)c1 -US06888000B2,6,CCCCc1nc2cnc3ccccc3c2n1CCCNC(=O)OC(C)(C)C>>CCCCc1nc2cnc3ccccc3c2n1CCCN -US20150057274A1,9,O=Cc1sccc1Br.[N-]=[N+]=[N-]>>[N-]=[N+]=Nc1ccsc1C=O -US07601850B2,7,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc(C)cs1>>CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1cc(C)cs1 -US04421758,7,O=C(OC[C@H]1CCC[C@H](OC(Cn2ccnc2)c2ccc(Cl)cc2Cl)O1)c1ccccc1>>OC[C@H]1CCC[C@H](OC(Cn2ccnc2)c2ccc(Cl)cc2Cl)O1 -US20120028950A1,1,Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1cccc(Br)c1.N#CC1CCNCC1>>Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1cccc(N2CCC(C#N)CC2)c1 -US20140275004A1,3,CC1(C)OB(C2=CCN(S(C)(=O)=O)CC2)OC1(C)C.O=S(=O)(c1ccccc1)n1c(I)cc2c(Cl)ncnc21>>CS(=O)(=O)N1CC=C(c2cc3c(Cl)ncnc3n2S(=O)(=O)c2ccccc2)CC1 -US05990105,1,CN.O=S(=O)(c1cccc(C(F)(F)F)c1)c1cc(Br)nc(Br)c1>>CNc1cc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cc(Br)n1 -US06465466B1,7,Cc1cc2nc3c4cc([N+](=O)[O-])ccc4n(CCN(C)C)c3nc2cc1C>>Cc1cc2nc3c4cc(N)ccc4n(CCN(C)C)c3nc2cc1C -US20100286145A1,1,CI.COC(=O)c1cccc(C(=O)Nc2nc(C)cs2)c1>>COC(=O)c1cccc(C(=O)N(C)c2nc(C)cs2)c1 -US07994336B2,2,CC(C)(C)OC(=O)NCC1CCN1.O=C(O)c1ccccc1-c1ccccc1>>CC(C)(C)OC(=O)NCC1CCN1C(=O)c1ccccc1-c1ccccc1 -US20090247559A1,1,O=C(CBr)CNCC1CC1.O=Cc1cccc(O)c1>>O=Cc1cccc(OCC(=O)CNCC2CC2)c1 -US20110166121A1,1,CC(C)(C)OC(=O)NCCO[Si](C)(C)C(C)(C)C.CI>>CN(CCO[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C -US20080027070A1,2,Cc1cc(C(=O)Cl)no1.Nc1ccc(Cl)c(C(=O)O)c1>>Cc1cc(C(=O)Nc2ccc(Cl)c(C(=O)O)c2)no1 -US07589206B2,6,COC(=O)c1cnc(Cl)c2ccn(C)c12>>Cn1ccc2c(Cl)ncc(C(=O)O)c21 -US20150080438A1,1,CNCCCCS(=O)(=O)CCC(F)(F)F.Oc1cccc(C2=C(CCCCCCBr)c3ccc(O)cc3CCC2)c1>>CN(CCCCCCC1=C(c2cccc(O)c2)CCCc2cc(O)ccc21)CCCCS(=O)(=O)CCC(F)(F)F -US08546427B2,2,CC1(C)CC(c2ccccc2N)Nc2ccc(C#N)cc21.CS(=O)(=O)Cl>>CC1(C)CC(c2ccccc2NS(C)(=O)=O)Nc2ccc(C#N)cc21 -US20110230497A1,6,CCOC(=O)CC1CCN2C(=O)CCC2C1>>O=C(O)CC1CCN2C(=O)CCC2C1 -US20050065179A1,2,CC(C)(C(=O)O)c1ccc([N+](=O)[O-])c(Cl)c1.CC(C)CNCC(C)C>>CC(C)CN(CC(C)C)C(=O)C(C)(C)c1ccc([N+](=O)[O-])c(Cl)c1 -US20100298287A1,9,Cc1cc(N(C)C)ncc1N.S=C(Cl)Cl>>Cc1cc(N(C)C)ncc1N=C=S -US05597848,3,COC(=O)CCCCc1ccccc1.O=C(Cl)Cc1ccccc1>>COC(=O)CCCCc1ccc(C(=O)Cc2ccccc2)cc1 -US08324221B2,6,CC(=O)NCc1cccc2c1C1(CCN(Cc3ccccc3)CC1)CN2c1ncnc2c1[C@H](C)C[C@H]2O>>CC(=O)NCc1cccc2c1C1(CCNCC1)CN2c1ncnc2c1[C@H](C)C[C@H]2O -US05942511,1,C=CCS.OCCOc1ccc(Cl)nn1>>C=CCSc1ccc(OCCO)nn1 -US20150166595A1,1,C1COCCN1.O=[N+]([O-])c1ccc(CBr)cc1>>O=[N+]([O-])c1ccc(CN2CCOCC2)cc1 -US05807889,7,CCCN(CCC)CC1CCc2ccc(NC(C)=O)cc21>>CCCN(CCC)CC1CCc2ccc(NCC)cc21 -US07482484B2,2,CCCCC#Cc1cc2c(cc1N)C(=O)CC2.O=C(O)C(F)(F)F>>CCCCC#Cc1cc2c(cc1NC(=O)C(F)(F)F)C(=O)CC2 -US20100075968A1,6,COC(=O)C1CN(c2cccnc2)C(=O)N1C>>CN1C(=O)N(c2cccnc2)CC1C(=O)O -US20100056524A1,1,CC(C)(C)OC(=O)NCCCBr.O=C1CCCCN1>>CC(C)(C)OC(=O)NCCCN1CCCCC1=O -US20020128477A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Fc1ccc2[nH]cc(CC3CCNCC3)c2c1>>CC(C)(C)OC(=O)N1CCC(Cc2c[nH]c3ccc(F)cc23)CC1 -US20110301142A1,1,Brc1ccc2[nH]ccc2c1.CCOC(=O)CBr>>CCOC(=O)Cn1ccc2cc(Br)ccc21 -US20100063068A1,2,CN.COc1ccc2sc(-c3ccc(F)cc3)c(C(=O)O)c2c1>>CNC(=O)c1c(-c2ccc(F)cc2)sc2ccc(OC)cc12 -US06218427B1,6,COC(=O)C1=C(c2ccc3c(c2)OCO3)c2cc(OC(C)C)ccc2OC1c1ccc2c(c1)OCO2>>CC(C)Oc1ccc2c(c1)C(c1ccc3c(c1)OCO3)=C(C(=O)O)C(c1ccc3c(c1)OCO3)O2 -US08436023B2,1,CC(C)C1CCC(=O)CC1.O=C(CNc1n[nH]c2ccc(C(F)(F)F)cc12)NC1CNC1>>CC(C)C1CCC(N2CC(NC(=O)CNc3n[nH]c4ccc(C(F)(F)F)cc34)C2)CC1 -US07732461B2,3,C=O.COC(=O)Cc1c(F)cnc2ccc(OC)nc12>>C=C(C(=O)OC)c1c(F)cnc2ccc(OC)nc12 -US09018382B2,3,CN(C)c1ccc(B(O)O)cn1.Cc1cc(C)c(CNC(=O)c2cc(Br)cc3c2cnn3C(C)C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N(C)C)nc3)cc3c2cnn3C(C)C)c(=O)[nH]1 -US20060211603A1,2,CC(C)(C)OC(=O)CN.CCCCC(=O)O>>CCCCC(=O)NCC(=O)OC(C)(C)C -US20110009389A1,6,CN(C)Cc1ncc2n1C(=O)N(C1CCN(Cc3ccccc3)CC1)C2>>CN(C)Cc1ncc2n1C(=O)N(C1CCNCC1)C2 -US20070066542A1,9,[N-]=[N+]=Nc1ccc(-c2c[nH]c(COc3ccccc3)n2)cc1>>Nc1ccc(-c2c[nH]c(COc3ccccc3)n2)cc1 -US07618970B2,6,CCOC1COCCC1(OC)OC>>CCOC1COCCC1=O -US20110059957A1,6,CC(=O)N1CCN(c2ccc(CCc3csc(CCCNC(=O)NNC(=O)OC(C)(C)C)c3)nc2)CC1>>CC(=O)N1CCN(c2ccc(CCc3csc(CCCNC(=O)NN)c3)nc2)CC1 -US20100137313A1,1,CSc1nc(Cl)ncc1Br.Nc1cc(F)cc(F)c1>>CSc1nc(Nc2cc(F)cc(F)c2)ncc1Br -US20120022044A1,6,COC(=O)c1ccc(Br)cc1OC>>COc1cc(Br)ccc1C(=O)O -US06608218B2,6,COC(=O)C(SC1CCCC1)c1ccc(Cl)c(Cl)c1>>O=C(O)C(SC1CCCC1)c1ccc(Cl)c(Cl)c1 -US20050267095A1,1,CN(C)CC1(c2ccc(O)cc2)CCOCC1.ClCCCN1CCSCC1>>CN(C)CC1(c2ccc(OCCCN3CCSCC3)cc2)CCOCC1 -US07220773B2,1,CC(=O)Oc1cccc(O)c1.CCOC(=O)CBr>>CCOC(=O)COc1cccc(OC(C)=O)c1 -US20090069340A1,10,CCc1c(C)n(C)n(-c2ccccc2)c1=O.O=C1CCC(=O)N1Br>>CCc1c(CBr)n(C)n(-c2ccccc2)c1=O -US08415345B2,9,O=S(=O)(Nc1cccc(-c2nc(N3CCOCC3)sc2-c2ccnc(Cl)n2)c1Cl)c1ccoc1.[NH4+]>>Nc1nccc(-c2sc(N3CCOCC3)nc2-c2cccc(NS(=O)(=O)c3ccoc3)c2Cl)n1 -US20110009454A1,7,CCc1ccc(Oc2cccc(C#N)c2)cc1>>CCc1ccc(Oc2cccc(CN)c2)cc1 -US04772600,2,CN.O=C(O)Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2cccnc21>>CNC(=O)Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2cccnc21 -US04405787,2,COC(=O)C1NC2CCC1C2.COC(=O)CCC(C)C(=O)O>>COC(=O)CCC(C)C(=O)N1C2CCC(C2)C1C(=O)OC -US20120289522A1,3,Brc1ccncc1.C=CCC(O)c1c(C)noc1-c1ccc(-c2ccc(C3(C(=O)OCC)CC3)cc2)cc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C/C=C/c4ccncc4)cc3)cc2)CC1 -US20090264336A1,2,C1CNC1.O=S(=O)(Cl)c1cnc(Cl)c(Br)c1>>O=S(=O)(c1cnc(Cl)c(Br)c1)N1CCC1 -US20090029963A1,2,C1CCN(C2CCNCC2)C1.Cc1c(C(=O)O)c(C(F)(F)F)nn1-c1cccc(C(F)(F)F)c1>>Cc1c(C(=O)N2CCC(N3CCCC3)CC2)c(C(F)(F)F)nn1-c1cccc(C(F)(F)F)c1 -US04073786,1,CCC(N)(CC)C(CO)=NO.Nc1nc(O)c([N+](=O)[O-])c(Cl)n1>>CCC(CC)(Nc1nc(N)nc(O)c1[N+](=O)[O-])C(CO)=NO -US05286869,2,C/C(=C\CO)c1ccc(Cc2ncc[nH]2)cc1.COC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc([N+](=O)[O-])c1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC/C=C(\C)c2ccc(Cc3ncc[nH]3)cc2)C1c1cccc([N+](=O)[O-])c1 -US20040167128A1,1,BrCc1ccccc1.Cc1c(Br)ccc(NC(=O)OC(C)(C)C)c1C(=O)O>>Cc1c(Br)ccc(NC(=O)OC(C)(C)C)c1C(=O)OCc1ccccc1 -US20070259965A1,2,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCCN.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCCCNS(=O)(=O)c1ccc(Cl)cc1Cl -US06380238B1,1,Brc1ccc2cc[nH]c2c1.NCCCl>>NCCn1ccc2ccc(Br)cc21 -US04111936,6,CNC(=O)CCC(=O)c1c(OC)cccc1OC>>CNC(=O)CCC(=O)c1c(O)cccc1OC -US20100256097A1,3,C#Cc1cccc(Br)n1.CC(C)=O>>CC(C)(O)C#Cc1cccc(Br)n1 -US08394986B2,6,CCS(=O)(=O)c1ccc(Sc2cc(Cl)ccc2OC)cc1>>CCS(=O)(=O)c1ccc(Sc2cc(Cl)ccc2O)cc1 -US20080185577A1,3,Fc1c(F)c(F)c(Br)c(F)c1F.O=[N+]([O-])c1ccc(I)cc1>>O=[N+]([O-])c1ccc(-c2c(F)c(F)c(F)c(F)c2F)cc1 -US20120004233A1,6,CCOC(=O)Cc1c2c(c3ccccn13)CC(N(C)S(=O)(=O)c1ccc(F)cc1)CC2>>CN(C1CCc2c(c3ccccn3c2CC(=O)O)C1)S(=O)(=O)c1ccc(F)cc1 -US20030088103A1,7,CCOC(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(F)c(F)c1>>CCOC(=O)c1cc(N)ccc1Oc1ccc(F)c(F)c1 -US20150274720A1,1,CC(C)(C)OC(=O)N1CCNCC1.Oc1nc(-c2ccnc(Cl)c2)nc2cncc(Cl)c12>>CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccnc(Cl)c3)nc3cncc(Cl)c23)CC1 -US07192950B2,7,COc1cc2c(cc1OC)C(Cc1ccc(Cl)c(Cl)c1)=NCC(=O)N2>>COc1cc2c(cc1OC)C(Cc1ccc(Cl)c(Cl)c1)NCC(=O)N2 -US20030144333A1,6,CCOC(=O)C(=O)c1sccc1I>>O=C(O)C(=O)c1sccc1I -US20060252790A1,2,CC(C)(N)CO.CCn1ncc2c(NC3CCOCC3)c(C(=O)O)cnc21>>CCn1ncc2c(NC3CCOCC3)c(C(=O)NC(C)(C)CO)cnc21 -US07432258B2,2,COc1ccc(O)c(N)c1.O=C(Br)CBr>>COc1ccc(O)c(NC(=O)CBr)c1 -US06693101B2,7,COc1ccc(CNc2cccc(CCCCC(=O)C=Cc3cnc4ccccc4n3)n2)cc1>>COc1ccc(CNc2cccc(CCCCC(O)C=Cc3cnc4ccccc4n3)n2)cc1 -US07432288B2,1,COc1ccc(NC2=C(c3ccccc3)C(=O)NC2=O)cc1.Cc1cc(CO)no1>>COc1ccc(NC2=C(c3ccccc3)C(=O)N(Cc3cc(C)on3)C2=O)cc1 -US20110130398A1,6,CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Br)c2F)C12C(=O)Nc1cc(Cl)ccc12>>CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Br)c2F)C12C(=O)Nc1cc(Cl)ccc12 -US20130231333A1,8,OCC#Cc1ccc2c(cnn2C2CCCCO2)c1>>O=CC#Cc1ccc2c(cnn2C2CCCCO2)c1 -US07705030B2,6,CN1C(=O)C(c2cccc(OCc3ccccc3)c2)(c2cnn(CC(F)(F)F)c2)N=C1N>>CN1C(=O)C(c2cccc(O)c2)(c2cnn(CC(F)(F)F)c2)N=C1N -US20090156646A1,6,CC(C)(C)OC(=O)NCCC(=O)Nc1cccc(-c2cc(-c3ccccc3O)nc(NC(=O)c3ccccc3)c2C#N)c1>>N#Cc1c(-c2cccc(NC(=O)CCN)c2)cc(-c2ccccc2O)nc1NC(=O)c1ccccc1 -US07790720B2,2,C1COCCN1.O=C(O)c1coc(-c2ccc(OCCCCl)cc2)n1>>O=C(c1coc(-c2ccc(OCCCCl)cc2)n1)N1CCOCC1 -US20040121965A1,1,CC(C)(C(=O)C(=O)O)c1cccc(Br)c1.CN>>CN[C@H](C(=O)O)C(C)(C)c1cccc(Br)c1 -US20140349989A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1ccc(I)cc1>>CCOC(=O)/C=C/c1ccc(I)cc1 -US20080255105A1,2,Cc1ccc(N)cc1Br.O=C(Cl)C1CC1>>Cc1ccc(NC(=O)C2CC2)cc1Br -US04827004,8,C=C(C)C(CC/C(C)=C/CCC(C)=CCO)O[Si](C)(C)C(C)(C)C>>C=C(C)C(CC/C(C)=C/CCC(C)=CC=O)O[Si](C)(C)C(C)(C)C -US20070219235A1,6,Cc1cccnc1Nc1nc2cc(C(=O)Nc3ccc4cn[nH]c4c3)c(N3CCC(NC(=O)OC(C)(C)C)CC3)cc2[nH]1>>Cc1cccnc1Nc1nc2cc(C(=O)Nc3ccc4cn[nH]c4c3)c(N3CCC(N)CC3)cc2[nH]1 -US20130123235A1,3,CCCC[Sn](/C=C\CN(CC)CC)(CCCC)CCCC.COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2Br)ccc2c1OCc1occ(F)c1-2>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)OCc1occ(F)c1-2 -US05482967,1,C=O.Cc1cc(C)cc(CNC2CCCn3c2c(-c2ccccc2)c2cc(C)c(C)cc2c3=O)c1>>Cc1cc(C)cc(CN(C)C2CCCn3c2c(-c2ccccc2)c2cc(C)c(C)cc2c3=O)c1 -US08173821B2,2,CC(C)(C)OC(=O)N1CC[C@H](C(=O)O)C1.CNOC>>CON(C)C(=O)[C@H]1CCN(C(=O)OC(C)(C)C)C1 -US20150189880A1,1,CCS.CN(C(=O)c1ncc(Cl)cc1Cl)c1ccc(SC(F)(F)F)cc1>>CCSc1cc(Cl)cnc1C(=O)N(C)c1ccc(SC(F)(F)F)cc1 -US20120129854A1,1,COC(=O)c1cccc2nc(Cl)sc12.FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CCNC1>>COC(=O)c1cccc2nc(N3CCC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)sc12 -US04120962,3,N#CCC(N)=O.O=Cc1cc(Cl)ccc1[N+](=O)[O-]>>N#CC(=Cc1cc(Cl)ccc1[N+](=O)[O-])C(N)=O -US20080161280A1,2,CNOC.O=C(O)Cc1cccc(Br)c1>>CON(C)C(=O)Cc1cccc(Br)c1 -US04725600,1,CNCc1ccccc1.COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c(Cl)n2)cc1OC>>COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c(N(C)Cc3ccccc3)n2)cc1OC -US20020107272A1,1,CC(C)N1C(=O)NC(=CN(C)C)C1=O.COc1ccc(CCl)cc1>>COc1ccc(CN2C(=O)N(C(C)C)C(=O)C2=CN(C)C)cc1 -US08129361B2,7,OCC#Cc1ccc(C(F)(F)F)cc1Cl>>OCCCc1ccc(C(F)(F)F)cc1Cl -US05432182,1,COCCCl.Cc1ccccc1Nc1c(C(=O)C(C)C)cnc2c(O)cccc12>>COCCOc1cccc2c(Nc3ccccc3C)c(C(=O)C(C)C)cnc12 -US20090018166A1,2,CCCC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCC1=O.CN(c1ccccc1)S(N)(=O)=O>>CCCC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)N(C)c3ccccc3)CC2)nc1CN1CCCC1=O -US07557213B2,3,CCc1ccc(I)cn1.CON(C)C(=O)c1cn(Cc2cccc(Cl)c2)c2ccccc2c1=O>>CCc1ccc(C(=O)c2cn(Cc3cccc(Cl)c3)c3ccccc3c2=O)cn1 -US08106091B2,7,CC(C)(C)OC(=O)N[C@@H](CC#Cc1ccc(Br)cc1)C(=O)OC1CCCC1>>CC(C)(C)OC(=O)N[C@@H](C/C=C\c1ccc(Br)cc1)C(=O)OC1CCCC1 -US08138175B2,1,COC[C@H](CC=O)N1CCN(c2cccc(C(F)(F)F)c2)CCC1=O.C[C@@H]1CNC[C@@H](O)C1>>COC[C@H](CCN1C[C@@H](C)C[C@H](O)C1)N1CCN(c2cccc(C(F)(F)F)c2)CCC1=O -US20120208815A1,2,CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCc2ccccc2)CC[C@@H]1O.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCc2ccccc2)CC[C@@H]1OS(C)(=O)=O -US08258160B2,4,C#CCCC1CCCCC1.Cc1nc(N=[N+]=[N-])sc1C(=O)NCc1ccccc1>>Cc1nc(-n2cc(CCC3CCCCC3)nn2)sc1C(=O)NCc1ccccc1 -US04771046,6,CN1CCN(C(=O)OC(C)(C)C)CC1=O>>CN1CCNCC1=O -US08921397B2,2,CS(=O)(=O)CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CS(=O)(=O)CC(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1 -US20100063294A1,7,COC(=O)[C@@H](C)Cc1ccccc1>>C[C@H](CO)Cc1ccccc1 -US05686442,6,CCOC(=O)c1c(C(=O)c2cc(OC)c(C)cc2[N+](=O)[O-])nnn1Cc1ccc(OC)cc1>>COc1ccc(Cn2nnc(C(=O)c3cc(OC)c(C)cc3[N+](=O)[O-])c2C(=O)O)cc1 -US07282496B2,6,CC=C=CCOc1ccc(S(=O)(=O)N(C)C(C(=O)OC)C(C)C)cc1>>CC=C=CCOc1ccc(S(=O)(=O)N(C)[C@H](C(=O)O)C(C)C)cc1 -US20050215563A1,3,CC(C)Cc1cc(CCC#N)ccc1-c1ccc(OS(=O)(=O)C(F)(F)F)c(Cc2cccc3ccccc23)c1.COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1CC(C)C>>COc1ccc(-c2ccc(-c3ccc(CCC#N)cc3CC(C)C)cc2Cc2cccc3ccccc23)cc1CC(C)C -US04888439,2,CC(C)NC(C)C.CCOC(=O)C=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C(=O)O>>CCOC(=O)C=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C(=O)N(C(C)C)C(C)C -US20130324531A1,2,COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F.OCCOCCO>>COc1cc(C(=O)OCCOCCO)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F -US20130045975A1,1,BrCCOC1CCCCO1.COC(=O)c1ccc(OC)c(OC2CCCC2)c1NC(C)=O>>COC(=O)c1ccc(OC)c(OC2CCCC2)c1N(CCOC1CCCCO1)C(C)=O -US20090029994A1,1,CC(C)(C)OC(=O)CCCOc1cnc(Cl)nc1.COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN>>COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CNc1ncc(OCCCC(=O)OC(C)(C)C)cn1 -US08349836B2,7,COC(=O)c1cc(Br)c(C)c(Br)c1>>Cc1c(Br)cc(CO)cc1Br -US04001426,1,CCNCC.COc1c(C)cc(C(=O)c2c(-c3ccc(OCCBr)cc3)oc3ccccc23)cc1C>>CCN(CC)CCOc1ccc(-c2oc3ccccc3c2C(=O)c2cc(C)c(OC)c(C)c2)cc1 -US07662809B2,6,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCCN(C)c1ccccc1-3>>CN1CCCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc21 -US20140088078A1,6,CC(C)(C)OC(=O)N1CC[C@H](C(=O)OCc2ccccc2)C1>>O=C(OCc1ccccc1)[C@H]1CCNC1 -US20100004280A1,3,CC(=O)C(F)(F)F.O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)OCc1ccccc1>>CC(=CC(=O)OCc1ccccc1)C(F)(F)F -US07067534B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccc(Cl)cc3)CC2)c1.NNc1ccc(OC(F)(F)F)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCc3c(-c4ccc(Cl)cc4)[nH]c4ccc(OC(F)(F)F)cc34)CC2)c1 -US04616014,2,CC(C)(C)OC(=O)NCC(=O)O.Cc1nc(NN)nnc1-c1ccccc1>>Cc1nc(NNC(=O)CNC(=O)OC(C)(C)C)nnc1-c1ccccc1 -US20120225865A1,2,NN.O=C(O)[C@@H]1CC[C@@H](Oc2ccncn2)CC1>>NNC(=O)[C@@H]1CC[C@@H](Oc2ccncn2)CC1 -US20090030023A1,1,CCCI.Nc1nc(-c2ccco2)c(-c2ccc(=O)[nH]c2)c(-c2ccco2)n1>>CCCn1cc(-c2c(-c3ccco3)nc(N)nc2-c2ccco2)ccc1=O -US20100152235A1,6,CCOC(=O)CN1CCc2c(cccc2-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)C1>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CC(=O)O)C4)no2)cc1C#N -US20140073620A1,1,CC(C)(C)OC(=O)N1CCC(n2cc(N)cn2)C1.NC(=O)C1(c2ccccc2CCc2nc(Cl)ncc2Cl)CC1>>CC(C)(C)OC(=O)N1CCC(n2cc(Nc3ncc(Cl)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)C1 -US06759557B2,7,O=C1CCCCCCCCC=CCCCCCCC1O>>O=C1CCCCCCCCCCCCCCCCC1O -US20120245344A1,3,CC1(C)OB(C2=CCN(C(=O)OCc3ccccc3)CC2)OC1(C)C.OCc1ccc(Br)cn1>>O=C(OCc1ccccc1)N1CC=C(c2ccc(CO)nc2)CC1 -US07652022B2,1,C1CCNCC1.COc1cc([N+](=O)[O-])ccc1Br>>COc1cc([N+](=O)[O-])ccc1N1CCCCC1 -US20050234065A1,9,CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C(N)=O)C1CCC(NC(=O)OCc2ccccc2)CC1>>CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C#N)[C@@H]1CC[C@@H](NC(=O)OCc2ccccc2)CC1 -US04182758,2,CCOC(=O)C(=NOC)c1csc(N)n1.O=CO>>CCOC(=O)C(=NOC)c1csc(NC=O)n1 -US20050148646A1,9,N#Cc1ccc(-c2ccc(O)c(-c3nc4cc(C#N)ccc4[nH]3)c2)cc1>>N#Cc1ccc(-c2cccc(-c3nc4cc(C#N)ccc4[nH]3)c2)cc1 -US08658646B2,2,C[C@@H](NC(=O)OC(C)(C)C)C(=O)O.F[C@@H]1CCNC1>>C[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CC[C@@H](F)C1 -US04743614,6,COC(=O)[C@@H](NC(=O)[C@H](CC(=O)NC(c1ccc(OC)cc1)c1ccc(OC)cc1)NC(=O)OCc1ccccc1)[C@@H](C)NCCc1c[nH]cn1>>COc1ccc(C(NC(=O)C[C@H](NC(=O)OCc2ccccc2)C(=O)N[C@H](C(=O)O)[C@@H](C)NCCc2c[nH]cn2)c2ccc(OC)cc2)cc1 -US20070225292A1,10,COC(=O)c1ncccc1NC(=O)c1ccc(C)c2ccccc12.O=C1CCC(=O)N1Br>>COC(=O)c1ncccc1NC(=O)c1ccc(CBr)c2ccccc12 -US20150011551A1,9,N.O=[N+]([O-])c1ccc(Cl)cn1>>Nc1ccc([N+](=O)[O-])nc1 -US07449490B2,3,CC(=O)c1cccc(Cl)c1.CCOC(=O)CC#N>>CCOC(=O)C(C#N)=C(C)c1cccc(Cl)c1 -US06359145B1,2,CN.COC(=O)c1cn([C@H](CCc2cccc3ccccc23)[C@H](C)O)cn1>>CNC(=O)c1cn([C@H](CCc2cccc3ccccc23)[C@H](C)O)cn1 -US05962450,2,CN1Cc2c(C(=O)O)ncn2-c2cccc(Cl)c2C1=O.COC(=O)[C@@H](N)CO>>COC(=O)[C@H](CO)NC(=O)c1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2 -US20090062258A1,7,CCN(C(=O)c1csc([N+](=O)[O-])c1)c1ccccc1>>CCN(C(=O)c1csc(N)c1)c1ccccc1 -US08022068B2,2,CN.COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CC(C)(C)C(=O)O)C[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21>>CNC(=O)C(C)(C)C[C@H]1C[C@H](c2ccc(COC[C@@H](C)COC)cc2)[C@@H](OCc2ccc3c(c2)N(CCCOC)CCO3)CN1S(=O)(=O)c1ccc(C)cc1 -US20110046134A1,2,O=C(NCC(=O)N1CCNCC1)c1ccc(-c2ccccc2)cc1.O=C(O)c1cc(C(F)(F)F)ccc1C(F)(F)F>>O=C(NCC(=O)N1CCN(C(=O)c2cc(C(F)(F)F)ccc2C(F)(F)F)CC1)c1ccc(-c2ccccc2)cc1 -US06878712B1,2,CSc1ccc(Sc2ccc3c(c2)CCN3)cc1.C[C@@](O)(C(=O)O)C(F)(F)F>>CSc1ccc(Sc2ccc3c(c2)CCN3C(=O)[C@@](C)(O)C(F)(F)F)cc1 -US09012441B2,6,C=CCc1c(CC(=O)OCC)c2ccccc2n1C(=O)OC(C)(C)C>>C=CCc1c(CC(=O)O)c2ccccc2n1C(=O)OC(C)(C)C -US20110263584A1,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O.Cc1cnc(Br)cn1>>Cc1cnc(-c2ccc([C@H](C)N3CC[C@](CC(C)(C)O)(c4ccccc4)OC3=O)cc2)cn1 -US20090149445A1,3,Clc1ccc2c(c1)CCc1ccccc1C2=CBr.OB(O)c1ccc(O)cc1>>Oc1ccc(C=C2c3ccccc3CCc3cc(Cl)ccc32)cc1 -US07772247B2,2,COCCn1cnc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)c1.COc1ccccc1CC(=O)N=C=S>>COCCn1cnc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5OC)cc4F)c3s2)c1 -US20150087639A1,7,N#CCN1CCOCC1>>NCCN1CCOCC1 -US05880130,1,CN(C)CCCCl.Cc1cccc(Nc2cc(Nc3ccc(O)cc3)ncn2)c1>>Cc1cccc(Nc2cc(Nc3ccc(OCCCN(C)C)cc3)ncn2)c1 -US05563141,7,O=C(O)C1(O)C=CC(c2ccccc2)=CC1>>OCC1(O)C=CC(c2ccccc2)=CC1 -US03957782,2,CCCCN.CCOC(=O)c1nc2cnn(CC)c2nc1OCC>>CCCCNC(=O)c1nc2cnn(CC)c2nc1OCC -US20130045942A1,1,Cc1ccc([C@@H](C)N)cc1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>Cc1ccc([C@@H](C)Nc2ncnc3c2ncn3[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 -US20050154042A1,3,CC(C)(C)OC(=O)CC1CC(C=O)OC(C)(C)O1.CC(C)n1c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)NCc1ccc(COC(=O)C(C)(C)C)cc1>>CC(C)n1c(C=CC2CC(CC(=O)OC(C)(C)C)OC(C)(C)O2)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)NCc1ccc(COC(=O)C(C)(C)C)cc1 -US20110015157A1,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O.Cc1ncc(Br)cn1>>Cc1ncc(-c2ccc([C@H](C)N3CC[C@](CC(C)(C)O)(c4ccccc4)OC3=O)cc2)cn1 -US20100160441A1,6,CC1(C(=O)Nc2c(SC(=O)C3(C)CCCCC3)ccc3ccccc23)CCCCC1>>CC1(C(=O)Nc2c(S)ccc3ccccc23)CCCCC1 -US04696943,2,CC[C@H](N)C(N)=O.O=C(Cl)CCCCl>>CC[C@H](NC(=O)CCCCl)C(N)=O -US20030092712A1,7,Cc1cc([N+](=O)[O-])cnc1-c1ccc(F)cc1Cl>>Cc1cc(N)cnc1-c1ccc(F)cc1Cl -US07705030B2,6,C[Si](C)(C)C#Cc1ccc(OC(F)F)cc1>>C#Cc1ccc(OC(F)F)cc1 -US20130289033A1,3,Cc1cccc(B(O)O)c1.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1>>Cc1cccc(-c2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 -US07410976B2,1,CCI.COC(=O)c1cc(O)c2cccc(C3CC3)c2n1>>CCOc1cc(C(=O)OC)nc2c(C3CC3)cccc12 -US07414060B2,1,Cc1ccc(N)c(C(=O)Nc2csc(C)n2)n1.Fc1cncc(Br)c1>>Cc1ccc(Nc2cncc(F)c2)c(C(=O)Nc2csc(C)n2)n1 -US05506267,2,CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(N)cc1.CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)O)OC(=O)CCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)Nc1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)OC(C)(C)C)cc1)OC(=O)CCCCCCCCCCCCCCC -US20090118288A1,6,C[SH](C(=O)NC[C@H]1CN(Cc2ccc(Cl)cc2)CCO1)c1ccc(C(=O)OC(C)(C)C)cc1F>>C[SH](C(=O)NC[C@H]1CN(Cc2ccc(Cl)cc2)CCO1)c1ccc(C(=O)O)cc1F -US20120129843A1,4,CN1CCN(c2ccc(C(=O)CBr)cn2)CC1.COc1ccc(S(N)(=O)=O)cc1NC(N)=S>>COc1ccc(S(N)(=O)=O)cc1Nc1nc(-c2ccc(N3CCN(C)CC3)nc2)cs1 -US08344135B2,7,O=C(Nc1cccc([N+](=O)[O-])c1)c1cccc(C(F)(F)F)c1>>Nc1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1 -US05804601,9,CCOC(=O)CCCCC(=O)c1ccc2ccccc2c1.NO>>CCOC(=O)CCCCC(=NO)c1ccc2ccccc2c1 -US20070197577A1,2,COC(=O)c1cc(Oc2cccc(C(F)(F)F)c2)cc(Oc2cccc(C(F)(F)F)c2)c1.NN>>NNC(=O)c1cc(Oc2cccc(C(F)(F)F)c2)cc(Oc2cccc(C(F)(F)F)c2)c1 -US20110021479A1,2,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.COc1cc(-c2ncnc3c(C(=O)O)c[nH]c23)c(OCC2CC2)cc1F>>COc1cc(-c2ncnc3c(C(=O)N[C@@H]4CCCN(C(=O)OC(C)(C)C)C4)c[nH]c23)c(OCC2CC2)cc1F -US20140249127A1,3,CC(C)=O.O=Cc1ccc(Cl)c(F)c1>>CC(=O)CC(O)c1ccc(Cl)c(F)c1 -US20120295915A1,7,O=C(C1CC1)N1CC[C@@H](CNc2ccncc2[N+](=O)[O-])C1>>Nc1cnccc1NC[C@@H]1CCN(C(=O)C2CC2)C1 -US20090005370A1,2,COC(=O)c1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C(F)(F)F)c2)nc1.NCC(F)(F)F>>O=C(NCC(F)(F)F)c1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C(F)(F)F)c2)nc1 -US20150166512A1,2,CCOC(=O)c1[nH]ccc1-c1cc(Cl)ccc1C.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)c1c(-c2cc(Cl)ccc2C)ccn1S(=O)(=O)c1ccccc1 -US20110190269A1,2,CCOC(=O)Cl.COc1cc(Nc2nc3c(C4=CCNCC4)cc(C)cn3n2)ccc1-n1cnc(C)c1>>CCOC(=O)N1CC=C(c2cc(C)cn3nc(Nc4ccc(-n5cnc(C)c5)c(OC)c4)nc23)CC1 -US20140225069A1,1,CC(C)c1ccccc1N.Cc1cc([N+](=O)[O-])c(F)cc1-c1ccccc1>>Cc1cc([N+](=O)[O-])c(Nc2ccccc2C(C)C)cc1-c1ccccc1 -US20050070574A1,6,CCOC(=O)COc1ccc2c(C(=O)N[C@@H](CC)c3ccccc3)c(CN3CCC(N4CCCCC4)CC3)c(-c3ccccc3)nc2c1>>CC[C@H](NC(=O)c1c(CN2CCC(N3CCCCC3)CC2)c(-c2ccccc2)nc2cc(OCC(=O)O)ccc12)c1ccccc1 -US20080293712A1,6,COC(=O)c1cncc(O[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1>>CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(C(=O)O)c2)C1 -US08519135B2,2,COCN(c1cc(Cl)cnc1C(=O)c1ccccc1N)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1.CS(=O)(=O)Cl>>COCN(c1cc(Cl)cnc1C(=O)c1ccccc1NS(C)(=O)=O)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20130131018A1,1,CCOc1ccc2c(Cc3cc(OC)c(OC)c(OC)c3)cncc2c1OS(=O)(=O)C(F)(F)F.CN>>CCOc1ccc2c(Cc3cc(OC)c(OC)c(OC)c3)cncc2c1NC -US20050143452A1,9,COc1ccc(F)cc1C[C@H](O)COCc1ccccc1>>COc1ccccc1C[C@H](O)COCc1ccccc1 -US20100249084A1,2,CC(=O)O.Cc1cc(C)n(-c2nc(N)cc(Cl)n2)n1>>CC(=O)Nc1cc(Cl)nc(-n2nc(C)cc2C)n1 -US20100179216A1,7,OCC#Cc1cccs1>>OCCCc1cccs1 -US20090227600A1,2,CC(C)(C)OC(=O)[C@]1(Cc2cscn2)C[C@H](c2cnccn2)[C@H](c2nccs2)N1.COc1cc(C(=O)Cl)ccc1C(C)(C)C>>COc1cc(C(=O)N2[C@@H](c3nccs3)[C@@H](c3cnccn3)C[C@@]2(Cc2cscn2)C(=O)OC(C)(C)C)ccc1C(C)(C)C -US20030158185A1,6,CC(C)(C)OC(=O)NCC[C@@H](Oc1cc(Cl)c(F)cc1C#N)c1ccoc1>>N#Cc1cc(F)c(Cl)cc1O[C@H](CCN)c1ccoc1 -US09045475B2,1,NS(=O)(=O)c1ccc(NCCCNC2CC2)c([N+](=O)[O-])c1.O=C1COC1>>NS(=O)(=O)c1ccc(NCCCN(C2CC2)C2COC2)c([N+](=O)[O-])c1 -US20140057953A1,6,COc1cccc(-c2ccc(C(=O)N(C)Cc3ccccc3)s2)c1>>CN(Cc1ccccc1)C(=O)c1ccc(-c2cccc(O)c2)s1 -US08598355B2,3,COC(=O)c1cccc2ccn(Cc3ccc(B4OC(C)(C)C(C)(C)O4)cc3)c12.O=S(=O)(Oc1ccccn1)C(F)(F)F>>COC(=O)c1cccc2ccn(Cc3ccc(-c4ccccn4)cc3)c12 -US20110015157A1,1,C[C@@H](c1ccc(-c2ccc(F)cc2)cc1)N1CC[C@](CCO)(c2ccc(F)cc2)OC1=O.F[C@@H]1CCNC1>>C[C@@H](c1ccc(-c2ccc(F)cc2)cc1)N1CC[C@](CCN2CC[C@@H](F)C2)(c2ccc(F)cc2)OC1=O -US20070191431A1,2,CC(C)C(=O)Cl.CN1C(=O)C(c2cccc(-c3ccccc3)c2)(C2CCNCC2)N=C1N>>CC(C)C(=O)N1CCC(C2(c3cccc(-c4ccccc4)c3)N=C(N)N(C)C2=O)CC1 -US20100144694A1,1,CC1(C)NN(C2C3CC4CC(C3)CC2C4)C1=O.Cc1cccc(CBr)c1>>Cc1cccc(CN2N(C3C4CC5CC(C4)CC3C5)C(=O)C2(C)C)c1 -US20110003852A1,2,NC1C2CC3CC1CC(O)(C3)C2.O=C(O)c1ccc(OCS(=O)(=O)c2ccccn2)cc1>>O=C(NC1C2CC3CC1CC(O)(C3)C2)c1ccc(OCS(=O)(=O)c2ccccn2)cc1 -US05672596,2,CC(C)(NC(=O)OCc1ccccc1)C(=O)O.N[C@@H]1CCc2cc([N+](=O)[O-])ccc2NC1=O>>CC(C)(NC(=O)OCc1ccccc1)C(=O)N[C@@H]1CCc2cc([N+](=O)[O-])ccc2NC1=O -US04772600,2,CCOC(=O)CNc1ncccc1N.Cc1ccc(C(=O)Cl)s1>>CCOC(=O)CNc1ncccc1NC(=O)c1ccc(C)s1 -US07414060B2,1,Cc1ccc(N)c(C(=O)Nc2nc(C3CC3)cs2)n1.Fc1cncc(Br)c1>>Cc1ccc(Nc2cncc(F)c2)c(C(=O)Nc2nc(C3CC3)cs2)n1 -US20130331378A1,3,C=CB1OB(C=C)OB(C=C)O1.COC(=O)c1cccc(Cc2c(-c3ccccc3)nn3cc(Br)ccc23)n1>>C=Cc1ccc2c(Cc3cccc(C(=O)OC)n3)c(-c3ccccc3)nn2c1 -US06225309B1,2,CC(C)(C)OC(=O)NC(CN)Cc1ccccc1.O=C(Cl)C1CCN(c2ccncc2)CC1>>CC(C)(C)OC(=O)NC(CNC(=O)C1CCN(c2ccncc2)CC1)Cc1ccccc1 -US20090203699A1,7,CCOC(=O)c1cc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)nc1CN1CCCC1>>OCc1cc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)nc1CN1CCCC1 -US20070265193A1,1,COc1ccc(N(C(=O)CBr)C(C)C)cn1.O=C1Cc2nnc(C3CCCCC3)n2-c2ccccc2N1>>COc1ccc(N(C(=O)CN2C(=O)Cc3nnc(C4CCCCC4)n3-c3ccccc32)C(C)C)cn1 -US20080039476A1,7,CC1=NCCc2oc(C)cc21>>Cc1cc2c(o1)CCNC2C -US20140288046A1,1,C1CCNC1.CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1>>CC(C)(C)c1nc(N2CCCC2)c2nnn(Cc3ccccc3Cl)c2n1 -US20120232096A1,1,CCOc1c(C)c(Br)c(C)c2c1OC(C)C2.Fc1ccc(N2CCNCC2)cc1>>CCOc1c(C)c(N2CCN(c3ccc(F)cc3)CC2)c(C)c2c1OC(C)C2 -US20110172297A1,3,CC(C)S(=O)(=O)N[C@H]1CCOC[C@H]1c1ccc(I)cc1.N#Cc1ccc(B(O)O)s1>>CC(C)S(=O)(=O)N[C@H]1CCOC[C@H]1c1ccc(-c2ccc(C#N)s2)cc1 -US20090324581A1,2,CS(=O)(=O)Cl.OCCCc1ccc(F)cc1F>>CS(=O)(=O)OCCCc1ccc(F)cc1F -US06713645B1,9,COC(=O)c1cccc2c1c1c(O)cc(C)cc1n2Cc1cccc(C)c1.[NH4+]>>Cc1cccc(Cn2c3cc(C)cc(O)c3c3c(C(N)=O)cccc32)c1 -US20140187556A1,4,N#Cc1ccccc1-c1ccc([N+](=O)[O-])c(NCc2ccccc2)c1.[N-]=[N+]=[N-]>>O=[N+]([O-])c1ccc(-c2ccccc2-c2nnn[nH]2)cc1NCc1ccccc1 -US20050171140A1,3,COC(=O)c1c(C(C)C)nc(N)c(C=O)c1-c1ccc(F)cc1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>COC=Cc1c(N)nc(C(C)C)c(C(=O)OC)c1-c1ccc(F)cc1 -US20060241127A1,7,O=[N+]([O-])c1cc(F)c(O)c(F)c1>>Nc1cc(F)c(O)c(F)c1 -US20100143455A1,1,CCC(Br)CC.O=c1[nH]ncn1-c1ccc(N2CCN(c3ccc(SCC4COC(Cn5cncn5)(c5ccc(F)cc5F)C4)cc3)CC2)cc1>>CCC(CC)n1ncn(-c2ccc(N3CCN(c4ccc(SCC5COC(Cn6cncn6)(c6ccc(F)cc6F)C5)cc4)CC3)cc2)c1=O -US08327467B2,1,CC(C)(C)OC(=O)c1ccc(-c2cccc(Cl)c2)cc1N.Ic1ccc2c(c1)OCO2>>CC(C)(C)OC(=O)c1ccc(-c2cccc(Cl)c2)cc1Nc1ccc2c(c1)OCO2 -US20110268698A1,1,C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(O)cc3n2C2CCC2)cc1)C1CC1.Clc1ncccn1>>C[C@@H](OC(=O)Nc1ccc(-c2c(C#N)c3ccc(Oc4ncccn4)cc3n2C2CCC2)cc1)C1CC1 -US20070185161A1,3,CC[Mg+].O=C1CCc2cc(F)ccc21>>CCC1(O)CCc2cc(F)ccc21 -US08236835B2,10,Cc1nc(N2CCCCC2=O)sc1C(=O)NCc1ccccc1.O=C1CCC(=O)N1Br>>Cc1nc(N2CCCC(Br)C2=O)sc1C(=O)NCc1ccccc1 -US08030340B2,2,CS(=O)(=O)Cl.C[C@H]1N[C@@H]1c1ccccc1>>C[C@@H]1[C@@H](c2ccccc2)N1S(C)(=O)=O -US08236825B2,6,CC(C)C(=O)N1N=C(c2cccc(F)c2)SC1(CCCNC(=O)OC(C)(C)C)c1ccccc1>>CC(C)C(=O)N1N=C(c2cccc(F)c2)SC1(CCCN)c1ccccc1 -US05260307,2,N=C(N)N1CCCC(CN)C1.O=C(O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc2ccccc2c1>>N=C(N)N1CCCC(CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NS(=O)(=O)c2ccc3ccccc3c2)C1 -US08569522B2,2,CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)O)cc3)c(Cl)cc21.NCCc1ccc(Br)cc1Cl>>CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)NCCc4ccc(Br)cc4Cl)cc3)c(Cl)cc21 -US07279470B2,2,CN(C(=O)Cl)c1ccccc1.OCCc1ccc(O)cc1>>CN(C(=O)Oc1ccc(CCO)cc1)c1ccccc1 -US06982348B2,7,CCOC(=O)C(Cc1cccc(C(F)(F)F)c1)C(=O)c1ccc(F)cc1>>CCOC(=O)C(Cc1cccc(C(F)(F)F)c1)C(O)c1ccc(F)cc1 -US07696223B2,9,CCOC(=O)c1nc(Br)c2nc(C(C)(C)C)sc2c1O.[C-]#N>>CCOC(=O)c1nc(C#N)c2nc(C(C)(C)C)sc2c1O -US20090270361A1,2,CC(C)(C)N.Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Oc1ccc(C(=O)O)cc1>>Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Oc1ccc(C(=O)NC(C)(C)C)cc1 -US04699905,6,CC(C)(C)OC(=O)CN1C(=O)[C@@H](N2C(=O)c3ccccc3C2=O)CSC[C@H]1c1cccs1>>CC(C)(C)OC(=O)CN1C(=O)[C@@H](N)CSC[C@H]1c1cccs1 -US20060116393A1,1,COc1cc2c(cc1Br)CCN=C2.NCc1ccccc1>>COc1cc2c(cc1NCc1ccccc1)CCN=C2 -US04224325,6,Cc1nn(-c2ccc(Cl)nn2)c(C)c1N1C(=O)c2ccccc2C1=O>>Cc1nn(-c2ccc(Cl)nn2)c(C)c1N -US20150045356A1,2,O=C(Cl)C1CCCCC1.O=C1CCc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2N1>>O=C1CCc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2N1C(=O)C1CCCCC1 -US06900210B2,6,C[C@H](NC(=O)OC(C)(C)C)c1cccc(Oc2cncnc2)c1>>C[C@H](N)c1cccc(Oc2cncnc2)c1 -US20080318943A1,3,COc1cc(C)c(B2OC(C)(C)C(C)(C)O2)cn1.Nc1c2c(nc3c(Br)c(F)ccc13)CN(C1CCC1)C2=O>>COc1cc(C)c(-c2c(F)ccc3c(N)c4c(nc23)CN(C2CCC2)C4=O)cn1 -US04810800,7,N#Cc1nccn1Cc1cccs1>>NCc1nccn1Cc1cccs1 -US20130023541A1,1,CC(C)OC(=O)c1cccnc1N1CCNCC1.CCN(Cc1ccc(C=O)cn1)Cc1c(F)cccc1Cl>>CCN(Cc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cn1)Cc1c(F)cccc1Cl -US07629467B2,2,CC(C)(C)OC(=O)NN.O=C(O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC2CCC1C2>>CC(C)(C)OC(=O)NNC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC2CCC1C2 -US05298516,2,NCCO[N+](=O)[O-].O=C1NC(c2ccccc2)C(C(=O)O)O1>>O=C1NC(c2ccccc2)C(C(=O)NCCO[N+](=O)[O-])O1 -US07560558B2,3,Cc1ccc(O)c(C=O)n1.[Mg+]c1ccccc1>>Cc1ccc(O)c(C(O)c2ccccc2)n1 -US07863305B2,3,COC(=O)CC(=O)OC(C)(C)C.O=Cc1cccnc1>>COC(=O)C(=Cc1cccnc1)C(=O)OC(C)(C)C -US20120270824A1,3,CC(=O)OC[C@H]1O[C@H](Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.COC(=O)c1ncc(Br)cn1>>COC(=O)c1ncc(-c2ccc(O[C@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]3OC(C)=O)cc2)cn1 -US05792759,7,COC(=O)/C=C/[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](/C=C/CO)CC[C@@H]12 -US20050282862A1,1,Cc1ccc(NC(=O)c2cc(Cl)ccc2NCC2CCNCC2)nc1.O=C1CCCCC1>>Cc1ccc(NC(=O)c2cc(Cl)ccc2NCC2CCN(C3CCCCC3)CC2)nc1 -US20090221555A1,7,COc1ccc([N+](=O)[O-])c2c1CCCC(=O)N2>>COc1ccc(N)c2c1CCCC(=O)N2 -US04539324,1,CSCCl.OCc1cccc2ccccc12>>CSCOCc1cccc2ccccc12 -US07419997B2,2,NC1CCCc2c1[nH]c1ccc(Br)cc21.O=C(Cl)OCc1ccccc1>>O=C(NC1CCCc2c1[nH]c1ccc(Br)cc21)OCc1ccccc1 -US07585888B2,3,CC(=O)Nc1cccc(B(O)O)c1.CNc1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(Br)ccc12>>CNc1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(-c3cccc(NC(C)=O)c3)ccc12 -US07662825B2,2,COc1ncc(Cl)nc1N.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>COc1ncc(Cl)nc1NS(=O)(=O)c1cccc(Cl)c1Cl -US05474994,1,COc1ccccc1N1CCNCC1.Cc1c(-c2ccccc2)oc2c(C(=O)CBr)cccc2c1=O>>COc1ccccc1N1CCN(CC(=O)c2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1 -US20130303518A1,3,CCN(CC)CCN1CCCc2[nH]c(C=O)c(C)c2C1=O.O=C1Cc2cc(S(=O)(=O)Cc3ccc(F)cc3)ccc2N1>>CCN(CC)CCN1CCCc2[nH]c(/C=C3\C(=O)Nc4ccc(S(=O)(=O)Cc5ccc(F)cc5)cc43)c(C)c2C1=O -US20140194408A1,2,CC1(C)Cc2cc(C(=O)O)n(CCN)c2C1>>CC1(C)Cc2cc3n(c2C1)CCNC3=O -US08486939B2,1,COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)nc(N2CCOCC2)n1.Nc1cccnn1>>COc1cccc2c1nc(C(F)F)n2-c1nc(Nc2cccnn2)nc(N2CCOCC2)n1 -US20020019569A1,2,CC(COCCCCCO)=NOC(C)(C)C.CS(=O)(=O)Cl>>CC(COCCCCCOS(C)(=O)=O)=NOC(C)(C)C -US20150232443A1,1,CC(C)(C)S(N)=O.O=C1CCC1>>CC(C)(C)S(=O)N=C1CCC1 -US20070244125A1,1,BrCC1CC1.CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)NCC4(F)COC4)cc3c2)CC1>>CC(C)N1CCN(C(=O)c2ccc3c(c2)cc(C(=O)NCC2(F)COC2)n3CC2CC2)CC1 -US05547920,2,CC(=O)Cl.Nc1nsnc1-c1c(Cl)cccc1Cl>>CC(=O)Nc1nsnc1-c1c(Cl)cccc1Cl -US09067898B1,7,CCOC(=O)C=C1CCc2cc(OC)ccc21>>CCOC(=O)CC1CCc2cc(OC)ccc21 -US20150274767A1,1,Cc1ccc(C(=O)OC[C@H]2O[C@H](Cl)C[C@@H]2OC(=O)c2ccc(C)cc2)cc1.Clc1ncnc2[nH]cc(Br)c12>>Cc1ccc(C(=O)OC[C@H]2O[C@H](n3cc(Br)c4c(Cl)ncnc43)C[C@@H]2OC(=O)c2ccc(C)cc2)cc1 -US08822448B2,2,CC(=O)Cl.CC(=O)c1cc(Br)c(C)cc1N>>CC(=O)Nc1cc(C)c(Br)cc1C(C)=O -US05977141,6,CC(=O)NC(CCCc1ccccc1)C(=O)O>>NC(CCCc1ccccc1)C(=O)O -US08846947B2,6,CCOC(=O)c1cncc2[nH]c(-c3ccccc3C(F)(F)F)nc12>>O=C(O)c1cncc2[nH]c(-c3ccccc3C(F)(F)F)nc12 -US20080261981A1,2,COC(=O)CCc1ccc(-c2ccc(CC(N)C(=O)N(C)C)cc2)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)CCc1ccc(-c2ccc(CC(NS(=O)(=O)c3ccc(C)cc3)C(=O)N(C)C)cc2)cc1 -US05496805,2,CC(=O)SCC(C)C(=O)Cl.N[C@@H](Cc1ccccc1)C(=O)O>>CC(=O)SCC(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O -US20040058907A1,2,NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1.O=C=Nc1ccc(Br)cc1>>O=C(NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1)Nc1ccc(Br)cc1 -US06642239B2,1,CN1CCNCC1.COC(=O)c1ccc(F)cc1>>COC(=O)c1ccc(N2CCN(C)CC2)cc1 -US07723367B2,1,C1CCNC1.N#Cc1ccc(C(F)(F)F)nc1Cl>>N#Cc1ccc(C(F)(F)F)nc1N1CCCC1 -US20100152160A1,1,CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)cc3)CC2)Oc2cc(O)c(Cl)cc21.COC(=O)CBr>>COC(=O)COc1cc2c(cc1Cl)N(C(=O)OC(C)(C)C)CC(C(=O)N1CCC(C#N)(Cc3ccc(F)cc3)CC1)O2 -US07572809B2,1,CC(=O)Nc1ccc(O)cc1.COc1ccc2c(Cl)nc(Nc3cc[nH]n3)cc2c1>>COc1ccc2c(Oc3ccc(NC(C)=O)cc3)nc(Nc3cc[nH]n3)cc2c1 -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)cc1)Oc1cccc(F)c1>>O=C(NCCOc1ccc(CC(Oc2cccc(F)c2)C(=O)O)cc1)c1ccc(-c2ccccn2)cc1 -US04851413,7,CC1=C(C)C(=O)C(C(=CCCCCC(=O)O)c2cccnc2)=C(C)C1=O>>CC1=C(C)C(=O)C(C(CCCCCC(=O)O)c2cccnc2)=C(C)C1=O -US04010279,7,CCOC(=O)C(C)(C)Oc1ccc(-c2ccc(CCNC(=O)c3cc(Cl)ccc3OC)cc2)cc1>>COc1ccc(Cl)cc1C(=O)NCCc1ccc(-c2ccc(OC(C)(C)CO)cc2)cc1 -US20060160879A1,6,CCOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)c2ccc(-c3ccc(CO)cc3)cc2n1Cc1cccc(Cl)c1>>O=C(Nc1c(C(=O)O)n(Cc2cccc(Cl)c2)c2cc(-c3ccc(CO)cc3)ccc12)c1ccc(Cl)cc1 -US20050197327A1,1,CCC(Br)c1nc(C)c(C)c(=O)n1Cc1ccccc1.Cc1ccc(C2CNCCN2)cc1>>CCC(c1nc(C)c(C)c(=O)n1Cc1ccccc1)N1CCNCC1c1ccc(C)cc1 -US20150021557A1,3,Clc1cccc(I)c1.OB(O)c1ccc(-c2ccccc2)cc1>>Clc1cccc(-c2ccc(-c3ccccc3)cc2)c1 -US20090093484A1,6,COC(=O)COc1ccc(OC/C=C(/c2ccc(Cl)cc2)c2ccc(C#CCN3CCN(C)CC3)cc2)cc1C>>Cc1cc(OC/C=C(/c2ccc(Cl)cc2)c2ccc(C#CCN3CCN(C)CC3)cc2)ccc1OCC(=O)O -US07687491B2,1,COC(=O)C1CNC1.Cc1cc(-c2nc(-c3ccc(CO)nc3C)no2)ccc1CC(C)C>>COC(=O)C1CN(Cc2ccc(-c3noc(-c4ccc(CC(C)C)c(C)c4)n3)c(C)n2)C1 -US08101647B2,1,CN(C)CCCl.O=C1N(Cc2ccc(O)cc2)c2ccccc2C12COc1cc3c(cc12)OCCO3>>CN(C)CCOc1ccc(CN2C(=O)C3(COc4cc5c(cc43)OCCO5)c3ccccc32)cc1 -US20150266859A1,6,COC(=O)CCNC(=O)c1ccc(N(Cc2ccc(-n3cc(C(F)(F)F)cn3)cc2C)C2CCCCC2)nc1>>Cc1cc(-n2cc(C(F)(F)F)cn2)ccc1CN(c1ccc(C(=O)NCCC(=O)O)cn1)C1CCCCC1 -US06809110B2,6,CCO[C@@H](Cc1c(C)cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C)C(=O)OC>>CCO[C@@H](Cc1c(C)cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C)C(=O)O -US04680301,7,CC1CCN(c2cc3nc(C(C)(C)C)sc3cc2[N+](=O)[O-])CC1>>CC1CCN(c2cc3nc(C(C)(C)C)sc3cc2N)CC1 -US05208247,1,CCCCCCCCCCCCCCBr.COC(=O)Cc1ccc(O)c(F)c1>>CCCCCCCCCCCCCCOc1ccc(CC(=O)OC)cc1F -US20140249132A1,7,COc1c(C(C)=O)cc(C)c(C#N)c1C1CN(C(=O)OC(C)(C)C)C1>>COc1c(C(C)O)cc(C)c(C#N)c1C1CN(C(=O)OC(C)(C)C)C1 -US08969354B2,6,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@@H](CCCCNC(=O)/C=C/C(=O)OC)C(=O)OC(C)(C)C>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@@H](CCCCNC(=O)/C=C/C(=O)OC)C(=O)O -US06491989B1,1,CCCCCCCCBr.CCCCCCCCOc1ccc(-c2ccc3c(O)c(F)c(F)cc3c2F)cc1>>CCCCCCCCOc1ccc(-c2ccc3c(OCCCCCCCC)c(F)c(F)cc3c2F)cc1 -US20120107273A1,4,CC(=O)C(Br)C(=O)OC(C)(C)C.NC(=S)N1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)[C@@H](C(=O)OCc2ccccc2)C1>>Cc1nc(N2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)[C@@H](C(=O)OCc3ccccc3)C2)sc1C(=O)OC(C)(C)C -US20090247502A1,6,COC(=O)c1cnc2c(c1)N(S(=O)(=O)N1CCC(C(F)(F)F)CC1)CCO2>>O=C(O)c1cnc2c(c1)N(S(=O)(=O)N1CCC(C(F)(F)F)CC1)CCO2 -US20130338367A1,2,Nc1cn(-c2cccnc2)nc1Cl.O=C(Cl)CCCCl>>O=C(CCCCl)Nc1cn(-c2cccnc2)nc1Cl -US06121307,6,COc1ccccc1OCCN(CCCc1c[nH]c2ccccc12)Cc1ccccc1>>COc1ccccc1OCCNCCCc1c[nH]c2ccccc12 -US20100331326A1,6,COC(OC)c1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O>>O=Cc1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O -US20130267499A1,3,C=CCN(C)c1nn(Cc2ccc(OC)cc2)cc1C(=O)N(C)OC.C=C[Mg+]>>C=CCN(C)c1nn(Cc2ccc(OC)cc2)cc1C(=O)C=C -US20110178064A1,3,C[C@H]1CN(c2ncc(Br)cc2C=O)C[C@@H](C)O1.OB(O)c1cn[nH]c1>>C[C@H]1CN(c2ncc(-c3cn[nH]c3)cc2C=O)C[C@@H](C)O1 -US20150119390A1,1,COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1.OCc1cccc(C2(O)CCOCC2)n1>>COc1cc(OCc2cccc(C3(O)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US07560558B2,6,COC(=O)CCCCCCCCC(=O)c1cc(C)ccc1OC>>COC(=O)CCCCCCCCC(=O)c1cc(C)ccc1O -US20120282629A1,1,NNc1ccc(I)cc1.O=Cc1cc(O)c(O)cc1O>>Oc1cc(O)c(C=NNc2ccc(I)cc2)cc1O -US20100222318A1,1,CN.CN(C)C(=O)c1ccc(-c2cnc(N)c(-c3nnc(-c4ccc(CBr)cc4)o3)n2)cc1>>CNCc1ccc(-c2nnc(-c3nc(-c4ccc(C(=O)N(C)C)cc4)cnc3N)o2)cc1 -US20080275018A1,2,CC(C)(C)OC(=O)NCCC[C@@H](CNC(=O)[C@@H](N)CCCNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C.CC(C)(C)OC(=O)NCCC[C@@H]1NC(=O)[C@@H](NC(=O)OC(C)(C)C)Cc2cc(ccc2O)-c2cccc(c2)C[C@@H](C(=O)O)NC1=O>>CC(C)(C)OC(=O)NCCC[C@@H](CNC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)[C@@H]1Cc2cccc(c2)-c2ccc(O)c(c2)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(=O)OC(C)(C)C)C(=O)N1)NC(=O)OC(C)(C)C -US20140107109A1,1,C[C@@]1(c2cc(Br)ccc2F)CS(=O)(=O)C2(CC(F)(F)C2)C(N)=N1.Cc1cc(Cl)cnc1C(N)=O>>Cc1cc(Cl)cnc1C(=O)Nc1ccc(F)c([C@]2(C)CS(=O)(=O)C3(CC(F)(F)C3)C(N)=N2)c1 -US06166006,8,Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CSc4ccccc4)cc2)CCO3)cc1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CS(=O)c4ccccc4)cc2)CCO3)cc1 -US20050038040A1,1,Brc1ccccn1.CCO[C@H]1CNC[C@H]1Nc1nc(CC)c(-c2ccc(OC)cc2C)nc1CC>>CCO[C@H]1CN(c2ccccn2)C[C@H]1Nc1nc(CC)c(-c2ccc(OC)cc2C)nc1CC -US08686004B2,2,CS(N)(=O)=O.Cc1nc(-c2cncc(F)c2)sc1-c1cc(C(=O)O)n(C)n1>>Cc1nc(-c2cncc(F)c2)sc1-c1cc(C(=O)NS(C)(=O)=O)n(C)n1 -US08288549B2,1,N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)O -US20120035370A1,2,CC[C@H](N)c1ccnc(S(C)(=O)=O)c1.O=C(O)c1cncc2c1cnn2-c1ccc(F)cc1>>CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1 -US20140336376A1,1,CC(=O)CBr.Fc1cc(S)c(Br)cc1F>>CC(=O)CSc1cc(F)c(F)cc1Br -US20090318465A1,1,CN(CCO)C(=O)OC(C)(C)C.COC(=O)C(Cc1ccc(O)cc1)(OC)C(=O)OC>>COC(=O)C(Cc1ccc(OCCN(C)C(=O)OC(C)(C)C)cc1)(OC)C(=O)OC -US07176310B1,2,CNc1ccccc1.O=C(O)COc1ncc(C(=O)Nc2ccc(F)cc2)cn1>>CN(C(=O)COc1ncc(C(=O)Nc2ccc(F)cc2)cn1)c1ccccc1 -US20130237537A1,2,CC(C)c1cccc(N)c1.CSc1ncc2c(n1)CCN(c1cccc(C(=O)O)n1)C2>>CSc1ncc2c(n1)CCN(c1cccc(C(=O)Nc3cccc(C(C)C)c3)n1)C2 -US20080188528A1,6,COC(=O)[C@H](CCCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CCC(C)(C)O2)NC(=O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCCC[C@H](NC(=O)c2cccn(C(c3ccccc3)c3ccccc3)c2=O)C(=O)O)c(C)c2c1OC(C)(C)CC2 -US04588727,2,CCOC(=O)Cl.Nn1cccc1C(=O)c1ccccc1Cl>>CCOC(=O)Nn1cccc1C(=O)c1ccccc1Cl -US20130116243A1,6,CN1C(=O)COc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(CC3CC3)cc21>>CN1C(=O)COc2nc(-c3ccc(C4(N)CCC4)cc3)c(CC3CC3)cc21 -US20120040981A1,6,COC(=O)c1sc(Br)cc1N>>Nc1cc(Br)sc1C(=O)O -US05760035,1,Cc1ccc(OCCBr)cc1.NCC1CCNCC1>>Cc1ccc(OCCN2CCC(CN)CC2)cc1 -US06204249B1,4,CC(C)N=C=S.Nc1cc(Cl)cc(Cl)c1N>>CC(C)Nc1nc2c(Cl)cc(Cl)cc2[nH]1 -US20010047038A1,1,Cc1cc2nc(S)[nH]c2cc1C.Nc1ccccc1CCl>>Cc1cc2nc(SCc3ccccc3N)[nH]c2cc1C -US20020127605A1,2,COC(=O)c1ccc(NC(=O)CCCCc2ccccc2)cc1.NN>>NNC(=O)c1ccc(NC(=O)CCCCc2ccccc2)cc1 -US05457115,1,Fc1ccc(I)cc1.O=C(O)c1cc2ccccc2[nH]1>>O=C(O)c1cc2ccccc2n1-c1ccc(F)cc1 -US20150210682A1,2,CCOc1cc(CC(N)CC)ccc1Cl.O=CO>>CCOc1cc(CC(CC)NC=O)ccc1Cl -US20120214785A1,3,C#Cc1ccc(CC(C)NC(C)=O)cc1.CSc1nccc(I)n1>>CSc1nccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)n1 -US20030149110A1,2,CC(C)(C)c1ccc(C(=O)O)cc1.NN>>CC(C)(C)c1ccc(C(=O)NN)cc1 -US20080051418A1,1,CC(C)Oc1cc(CCCO)n(Cc2ccc(Cl)cc2Cl)n1.CCOC(=O)c1sc(Cc2ccccc2)nc1O>>CCOC(=O)c1sc(Cc2ccccc2)nc1OCCCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1Cl -US06924300B2,7,COc1cc(C=O)cc(OC)c1OCc1nc(-c2ccccc2)oc1C>>COc1cc(CO)cc(OC)c1OCc1nc(-c2ccccc2)oc1C -US05212317,3,CN(C)C=O.Clc1ccc2ccccc2n1>>O=Cc1cc2ccccc2nc1Cl -US20040142850A1,2,CCOC(=O)N(Cc1cccc(Cl)c1)c1c(N)cc(N)cc1C(F)(F)F>>Nc1cc(C(F)(F)F)c2c(c1)[nH]c(=O)n2Cc1cccc(Cl)c1 -US20060293344A1,1,COCCN.COc1ccc(-c2nn3c(Cl)cccc3c2-c2ccnc(NC3CC3)n2)cc1>>COCCNc1cccc2c(-c3ccnc(NC4CC4)n3)c(-c3ccc(OC)cc3)nn12 -US04565769,6,COc1ccc(C(=O)c2ccc(N(C)C)cc2)cc1>>CN(C)c1ccc(C(=O)c2ccc(O)cc2)cc1 -US20150148340A1,1,NCc1ccccc1.O=C1CCc2c1cccc2C(F)(F)F>>FC(F)(F)c1cccc2c1CCC2NCc1ccccc1 -US20070249670A1,6,COC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C>>COC(=O)[C@H](CC(=O)O)NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C -US07452908B2,9,[N-]=[N+]=N[C@H]1C[C@@H](C(=O)N2CCC[C@@H]2C(=O)NC[C@H]2CCCN(CC3CCCCC3)C2)N(C(=O)CC(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>N[C@H]1C[C@@H](C(=O)N2CCC[C@@H]2C(=O)NC[C@H]2CCCN(CC3CCCCC3)C2)N(C(=O)CC(c2ccccc2)(c2ccccc2)c2ccccc2)C1 -US20130261133A1,3,C#C[C@@H](CCCCCCCCC)NCCCC.C/C=C/[C@H](O)C#CBr>>C/C=C/[C@H](O)C#CC#C[C@@H](CCCCCCCCC)NCCCC -US08841455B2,2,COCCOc1ccn2c(C(=O)O)cnc2c1.Nc1cccc2c1c(C1CC1)nn2Cc1ccccc1>>COCCOc1ccn2c(C(=O)Nc3cccc4c3c(C3CC3)nn4Cc3ccccc3)cnc2c1 -US20070161654A1,6,COCc1onc(-c2ccc(F)cc2)c1-c1cn(-c2ccc(C(F)(F)F)cc2)cn1>>OCc1onc(-c2ccc(F)cc2)c1-c1cn(-c2ccc(C(F)(F)F)cc2)cn1 -US07847045B2,1,C=C(C)C(=O)OC12CC3CC(CC(O)(C3)C1)C2.C=COCC>>C=C(C)C(=O)OC12CC3CC(C1)CC(OC(C)OCC)(C3)C2 -USRE045670E1,1,Cc1ccc(NC(=O)Nc2ncc(Br)s2)c(C(=O)C2CCCC2)c1.Cn1cnnc1S>>Cc1ccc(NC(=O)Nc2ncc(Sc3nncn3C)s2)c(C(=O)C2CCCC2)c1 -US06875765B2,1,BrCc1ccccc1.Oc1ccccc1Br>>Brc1ccccc1OCc1ccccc1 -US20110009454A1,2,Cc1ccc(Oc2cccc(CN)c2)cc1.Nc1ncccc1C(=O)O>>Cc1ccc(Oc2cccc(CNC(=O)c3cccnc3N)c2)cc1 -US20100240638A1,6,C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(F)c3C2)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)N(C)CCCCCCCCCCCC(=O)OC>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(F)c3C2)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)N(C)CCCCCCCCCCCC(=O)O -US06706751B2,1,BrCCCCBr.O=C(Oc1ccc(Cl)cc1)N1CCCc2cc(O)ccc21>>O=C(Oc1ccc(Cl)cc1)N1CCCc2cc(OCCCCBr)ccc21 -US04279918,2,CC(C)(C)C(=O)Cl.CN1CCCC1Cc1cccc(O)c1>>CN1CCCC1Cc1cccc(OC(=O)C(C)(C)C)c1 -US20150225405A1,1,CC1(C)OC[C@H](CN)O1.Cc1nc(Br)c([N+](=O)[O-])cc1Br>>Cc1nc(NC[C@H]2COC(C)(C)O2)c([N+](=O)[O-])cc1Br -US20120270875A1,2,CC(C)(C)CO.Cc1nc(NCCCc2cccc(O)c2)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O>>Cc1nc(NCCCc2cccc(O)c2)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)OCC(C)(C)C -US20120289505A1,2,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(N)cc3)ccc2C1=O.O=S(=O)(Cl)C1CCCCC1>>COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NS(=O)(=O)C4CCCCC4)cc3)ccc2C1=O -US08022221B2,1,Clc1nnc(-c2ccccc2)c2ccccc12.Nc1ccc(Oc2ncccc2B(O)O)cc1>>OB(O)c1cccnc1Oc1ccc(Nc2nnc(-c3ccccc3)c3ccccc23)cc1 -US08598156B2,6,Cn1nc(-c2ccc3c(c2)CCN3C(=O)OC(C)(C)C)c2c(N)ncnc21>>Cn1nc(-c2ccc3c(c2)CCN3)c2c(N)ncnc21 -US03956314,2,CCOC(=O)C(c1ccccc1)C(CN)c1ccc(Cl)cc1>>O=C1NCC(c2ccc(Cl)cc2)C1c1ccccc1 -US20120289522A1,3,Cc1noc(-c2ccc(Br)cc2)c1CNC(=O)OCc1ccccc1.O=C(O)c1cccc(B(O)O)c1>>Cc1noc(-c2ccc(-c3cccc(C(=O)O)c3)cc2)c1CNC(=O)OCc1ccccc1 -US20130079328A1,2,CC(=O)Cl.O=C(NCc1cnc(-c2ccnc(C(F)(F)F)c2)c(F)c1)c1ccc(N2CCNCC2)nc1>>CC(=O)N1CCN(c2ccc(C(=O)NCc3cnc(-c4ccnc(C(F)(F)F)c4)c(F)c3)cn2)CC1 -US07863291B2,3,COc1ncccc1B(O)O.Nc1cc(Br)ccn1>>COc1ncccc1-c1ccnc(N)c1 -US07790751B2,1,C=O.O=S(=O)(c1cccc2ccccc12)c1n[nH]c2ccc(OC3CCNC3)cc12>>CN1CCC(Oc2ccc3[nH]nc(S(=O)(=O)c4cccc5ccccc45)c3c2)C1 -US20100099677A1,6,CCOC(=O)CCCOc1c(-c2csc(C(=O)N3CCC(Cc4ccccc4)CC3)n2)cc(Br)c(O)c1Br>>O=C(O)CCCOc1c(-c2csc(C(=O)N3CCC(Cc4ccccc4)CC3)n2)cc(Br)c(O)c1Br -US20150225412A1,6,CC(C)(C)OC(=O)N1CCCC1CNc1ccc(C=O)cc1[N+](=O)[O-]>>O=Cc1ccc(NCC2CCCN2)c([N+](=O)[O-])c1 -US20150175604A1,1,C[O-].Cc1cc2c(cc(Cl)c3nnc(C)n32)n1Cc1ccccc1>>COc1cc2c(cc(C)n2Cc2ccccc2)n2c(C)nnc12 -US20060178359A1,6,CCCCOCCOc1ccc(-c2cc3c4c(c2)OCCN4CCCC(C(=O)OCC)=C3)cc1>>CCCCOCCOc1ccc(-c2cc3c4c(c2)OCCN4CCCC(C(=O)O)=C3)cc1 -US08288413B2,7,O=[N+]([O-])c1ccc(C2CC2)cc1NC1CCN(C2CCOCC2)CC1>>Nc1ccc(C2CC2)cc1NC1CCN(C2CCOCC2)CC1 -US07674907B2,1,ClCCN1CCCCC1.Oc1ccc(Br)cc1F>>Fc1cc(Br)ccc1OCCN1CCCCC1 -US07935688B2,6,CCC(CC)(c1ccc(CCC(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)cc2)c(C)c1>>CCC(CC)(c1ccc(CCC(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)O)cc2)c(C)c1 -US20040138286A1,1,CC=CCCl.O=C(NC1CCNCC1)c1ccc2[nH]ncc2c1>>CC=CCN1CCC(NC(=O)c2ccc3[nH]ncc3c2)CC1 -US04436748,6,COc1cc2cc(C(C)C)sc2c(Cl)c1Cl>>CC(C)c1cc2cc(O)c(Cl)c(Cl)c2s1 -US05112966,2,CO.COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)[C@H]([C@@H](C)O)[C@H]2C(=O)O)cc1>>COC(=O)[C@@H]1[C@@H]([C@@H](C)O)C(=O)N1C(Cc1ccc(OC)cc1)Cc1ccc(OC)cc1 -US20080318923A1,1,CN(C)C(=O)CN.COc1ccccc1C1(Cl)C(=O)Nc2ccc(Cl)cc21>>COc1ccccc1C1(NCC(=O)N(C)C)C(=O)Nc2ccc(Cl)cc21 -US07906522B2,1,C1CCNC1.O=[N+]([O-])c1ccnc(Cl)c1>>O=[N+]([O-])c1ccnc(N2CCCC2)c1 -US05434124,2,CN(C)S(=O)(=O)Cl.NS(=O)(=O)c1ccccc1O>>CN(C)S(=O)(=O)Oc1ccccc1S(N)(=O)=O -US20140107097A1,2,CC(=O)Cl.OC(c1cccnc1)(c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1)C1CCCNC1>>CC(=O)N1CCCC(C(O)(c2cccnc2)c2ccc3nc(Cl)c(-c4ccccc4)c(Cl)c3c2)C1 -US20090062251A1,2,CNC(=O)CCC[NH2+]C.Cn1c2c(c3cc(C(=O)O)ccc31)CC(C1CCOCC1)CC2>>CNC(=O)CCCN(C)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1 -US20040014968A1,2,Nc1ncccn1.O=C(O)C(CC1CCCC1)c1ccc(Cl)c(Cl)c1>>O=C(Nc1ncccn1)C(CC1CCCC1)c1ccc(Cl)c(Cl)c1 -US05861417,2,COc1ccc(-n2cnnn2)cc1C(=O)Cl.OCCC1(c2ccccc2)CCNC1>>COc1ccc(-n2cnnn2)cc1C(=O)N1CCC(CCO)(c2ccccc2)C1 -US20110301211A1,6,CCOC(=O)C(C)(C)c1ccc(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3F)cc2)cc1>>Cc1noc(-c2ccc(-c3ccc(C(C)(C)C(=O)O)cc3)cc2)c1NC(=O)OC(C)c1ccccc1F -US20020111492A1,6,CCOC(=O)C1(CCCc2c(Cl)cnc3ccc(OC)cc23)CCN(CCOc2nccs2)CC1>>COc1ccc2ncc(Cl)c(CCCC3(C(=O)O)CCN(CCOc4nccs4)CC3)c2c1 -US07687469B2,9,COc1ccc(C(O)c2ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)cc2)cc1Br>>COc1ccc(Cc2ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)cc2)cc1Br -US09120770B2,3,COc1ncc(CBr)cc1-c1cccc(Cl)c1.OB(O)c1cnc(Cl)nc1>>COc1ncc(Cc2cnc(Cl)nc2)cc1-c1cccc(Cl)c1 -US20090227566A1,6,COC(=O)c1ccc(-c2ccc(Cl)cc2)cc1OC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(Oc2cc(-c3ccc(Cl)cc3)ccc2C(=O)O)CC1 -US20070066617A1,2,Cc1cc(Br)ccc1C(=O)O.NCC(F)(F)F>>Cc1cc(Br)ccc1C(=O)NCC(F)(F)F -US07354934B2,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N[C@H]2CCCc3cccnc32)CC1.CC(C)(C)OC(=O)n1c(CCl)nc2ccccc21>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N(Cc2nc3ccccc3n2C(=O)OC(C)(C)C)C2CCCc3cccnc32)CC1 -US20110105470A1,1,Cc1ccc(CBr)cc1.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>Cc1ccc(CN2CCC3(CC2)CSC2=C(O3)c3ccccc3C(=O)C2=O)cc1 -US20110263571A1,2,CS(=O)(=O)c1cc(Br)ccc1C(=O)O.Clc1cnc(N2CCNCC2)c(Cl)c1>>CS(=O)(=O)c1cc(Br)ccc1C(=O)N1CCN(c2ncc(Cl)cc2Cl)CC1 -US20020119961A1,6,O=C1C2CCCC(C(=O)N1Cc1ccc(F)cc1)N2C(=O)OCc1ccccc1>>O=C1C2CCCC(N2)C(=O)N1Cc1ccc(F)cc1 -US08399436B2,1,CO.O=C(Nc1ccn(Cc2ccc(O)cc2Cl)n1)c1c(F)cccc1F>>COc1ccc(Cn2ccc(NC(=O)c3c(F)cccc3F)n2)c(Cl)c1 -US08710008B2,6,C=CCOC[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)OC)C(C)C)C(C)C>>C=CCOC[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)OC)C(C)C)C(C)C -US20140364432A1,6,Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CNC(=O)OC(C)(C)C)c(-c2ccc(F)cc2)s1>>Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CN)c(-c2ccc(F)cc2)s1 -US20080051430A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CCC(=O)c1cc(C)c(Cl)cc1OS(=O)(=O)C(F)(F)F>>CCC(=O)c1cc(C)c(Cl)cc1C1=CCN(C(=O)OC(C)(C)C)CC1 -US20090018104A1,1,BrCc1ccccc1.N#Cc1cc(Br)ccc1O>>N#Cc1cc(Br)ccc1OCc1ccccc1 -US20130143863A1,1,Brc1cccnc1.O=C1NCCc2cc(Cl)ccc21>>O=C1c2ccc(Cl)cc2CCN1c1cccnc1 -US07192968B2,2,CN1CCc2nc(C(=O)[O-])sc2C1.COC(=O)C1C[C@@H](N)[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)C1>>COC(=O)C1C[C@@H](NC(=O)c2nc3c(s2)CN(C)CC3)[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)C1 -US20140112945A1,2,CCOc1ccc(C[C@@H](N)C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)[C@H]4CCCC[C@H]4C3=O)CC2)cc1.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>CCOc1ccc(C[C@@H](NC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)[C@H]4CCCC[C@H]4C3=O)CC2)cc1 -US04281000,3,CN(C)C=O.c1cncc(-c2ccnc3ccnn23)c1>>O=Cc1cnn2c(-c3cccnc3)ccnc12 -US08168784B2,1,NS(=O)(=O)c1ccc(F)c(S(=O)(=O)C(F)(F)F)c1.N[C@H](CCN1CCOCC1)CSc1ccccc1>>NS(=O)(=O)c1ccc(N[C@H](CCN2CCOCC2)CSc2ccccc2)c(S(=O)(=O)C(F)(F)F)c1 -US20070276138A1,3,C#C[Si](C)(C)C.CCOC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)OC>>C#Cc1ccc(C[C@H](OC)C(=O)OCC)cc1 -US05387603,2,CC(=O)OC(C)=O.CCOc1ccccc1OCCN(C(=O)OC(C)(C)C)C(C)Cc1cc2c(c(C(N)=O)c1)NCC2>>CCOc1ccccc1OCCN(C(=O)OC(C)(C)C)C(C)Cc1cc2c(c(C(N)=O)c1)N(C(C)=O)CC2 -US04007175,2,CNC(=O)NC.O=C=Nc1ccccc1F>>CNC(=O)N(C)C(=O)Nc1ccccc1F -US07507733B2,2,Cc1c(Cl)cccc1S(=O)(=O)Cl.Nc1ccnc(C2CCC2)n1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1ccnc(C2CCC2)n1 -US20100216813A1,1,CC=O.Cc1ccccc1CN(c1ccc(C#N)c(Cl)c1)[C@H]1CCNC1>>CCN1CC[C@H](N(Cc2ccccc2C)c2ccc(C#N)c(Cl)c2)C1 -US20130129677A1,6,CC(C)(C)OC(=O)CN(C(=O)CCl)c1cccc(C(F)(F)F)c1>>O=C(O)CN(C(=O)CCl)c1cccc(C(F)(F)F)c1 -US04760163,1,CCOC(=O)c1cc(-n2c(=O)[nH]c3c(c2=O)CCC3)ccc1Cl.CI>>CCOC(=O)c1cc(-n2c(=O)c3c(n(C)c2=O)CCC3)ccc1Cl -US04499094,2,C1CCNCC1.O=C(O)c1cc2ccccc2c(-c2ccccc2Cl)n1>>O=C(c1cc2ccccc2c(-c2ccccc2Cl)n1)N1CCCCC1 -US05780501,1,BrCC1=Cc2ccccc2Oc2ccccc21.C#CCNC>>C#CCN(C)CC1=Cc2ccccc2Oc2ccccc21 -US08188102B2,6,COc1cc2ncnc(Nc3ccc(F)c(Cl)c3F)c2cc1O[C@H]1CCN(C(=O)OC(C)(C)C)[C@H](C(N)=O)C1>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3F)c2cc1O[C@H]1CCN[C@H](C(N)=O)C1 -US06194406B1,9,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(OC)c(OS(C)(=O)=O)c(OC)c4)C3)CC2)nc2ccccc21>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(OC)c(O)c(OC)c4)C3)CC2)nc2ccccc21 -US20020143011A1,3,COc1ccc(Br)cc1C=O.c1ccc([P+](c2ccccc2)(c2ccccc2)C2CCCC2)cc1>>COc1ccc(Br)cc1C=C1CCCC1 -US20150094330A1,2,COC(=O)c1ccc(CCc2cccc3c2NCC3)cc1.COc1cccc(S(=O)(=O)Cl)c1>>COC(=O)c1ccc(CCc2cccc3c2N(S(=O)(=O)c2cccc(OC)c2)CC3)cc1 -US08026248B2,1,Clc1cc(Cl)nc(Cl)n1.Oc1c(Cl)cccc1Cl>>Clc1cc(Oc2c(Cl)cccc2Cl)nc(Cl)n1 -US20120309739A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncc(Cl)nc4c3-c3ccccc3)cc2)CCC1.NC(=O)c1cccc(B(O)O)c1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncc(-c5cccc(C(N)=O)c5)nc4c3-c3ccccc3)cc2)CCC1 -US06541466B2,2,C[C@H](N)C(=O)C1(N)N=C(c2ccccc2)c2ccccc2N(C)C1=O.O=C(O)C(O)C1CCCC1>>C[C@H](NC(=O)C(O)C1CCCC1)C(=O)C1(N)N=C(c2ccccc2)c2ccccc2N(C)C1=O -US05811439,2,O=Cc1c[nH]c2ccccc12.O=S(=O)(Cl)c1ccc(F)cc1>>O=Cc1cn(S(=O)(=O)c2ccc(F)cc2)c2ccccc12 -US07049444B2,7,Cn1cc(CC(=O)N2CC3C(C2)C3(C)c2cccc(NS(C)(=O)=O)c2)c2ccccc21>>Cn1cc(CCN2CC3C(C2)C3(C)c2cccc(NS(C)(=O)=O)c2)c2ccccc21 -US08722629B2,1,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCCCO1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C.O=CCO>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCCCO1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCO)C(C)C -US20100249071A1,2,CCOC(=O)c1cn2ccsc2n1.NN>>NNC(=O)c1cn2ccsc2n1 -US20060167248A1,2,Cc1cc(N2CCOCC2)cc(C)c1N.O=C(Cl)OCc1ccccc1>>Cc1cc(N2CCOCC2)cc(C)c1NC(=O)OCc1ccccc1 -US04839365,8,CCOC(=O)OCn1c(SCc2nccc3ccsc23)nc2ccccc21.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)OCn1c(S(=O)Cc2nccc3ccsc23)nc2ccccc21 -US20110082164A1,3,Brc1cncc(Br)c1.OB(O)c1cccc(Cl)c1>>Clc1cccc(-c2cncc(Br)c2)c1 -US05482937,8,O=C(OCc1ccccc1)N1CCC(CCO)CC1>>O=CCC1CCN(C(=O)OCc2ccccc2)CC1 -US05262540,6,CCOC(=O)C=Cc1cccc(CCc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1>>O=C(O)C=Cc1cccc(CCc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 -US06982348B2,6,CC(C)(C)OC(=O)NC(Cc1cccc(CC(F)(F)C(F)F)c1)C(O)c1ccc(F)cc1>>NC(Cc1cccc(CC(F)(F)C(F)F)c1)C(O)c1ccc(F)cc1 -US20140213549A9,7,COc1ccc(COC2CC(C)(C)Cc3nc(C4CCN(c5ncc(C=O)cn5)CC4)c(C(F)c4ccc(C(F)(F)F)cc4)c(C4CCC(F)(F)CC4)c32)cc1>>COc1ccc(COC2CC(C)(C)Cc3nc(C4CCN(c5ncc(CO)cn5)CC4)c(C(F)c4ccc(C(F)(F)F)cc4)c(C4CCC(F)(F)CC4)c32)cc1 -US20120220572A1,1,CCNCC.O=C1Cc2ccccc2C1>>CCN(CC)C1Cc2ccccc2C1 -US08084448B2,3,C=Cn1cncn1.O=C1CN(c2ccc(I)cc2OCc2ccccc2)S(=O)(=O)N1>>O=C1CN(c2ccc(/C=C/n3cncn3)cc2OCc2ccccc2)S(=O)(=O)N1 -US20070129416A1,2,CCOc1cc(C(C)(C)C)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1.O=C(Cl)c1ccc(Cl)cc1>>CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)c1ccc(Cl)cc1 -US04383945,1,C=C(CC(=O)O)C[Si](C)(C)C.C=[N+]=[N-]>>C=C(CC(=O)OC)C[Si](C)(C)C -US20130150339A1,3,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(Cl)nccc3c2)cc1.OB(O)c1ccc(Cl)cc1O>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccc(Cl)cc4O)nccc3c2)cc1 -US07666888B2,2,CC(C)(O)[C@@H]1CCCNC1.COc1ccc(-c2nocc2C(=O)O)cc1>>COc1ccc(-c2nocc2C(=O)N2CCC[C@@H](C(C)(C)O)C2)cc1 -US08859545B2,6,FC(F)(F)c1ccc(Nc2ncnc3c2CN(Cc2ccccc2)CC3)cc1>>FC(F)(F)c1ccc(Nc2ncnc3c2CNCC3)cc1 -US20150011773A1,6,CC(C)(C)OC(=O)N[C@H](C[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@H](C[C@@H](Cc1ccc(O)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US05250554,4,CCCCc1nc2cccc(CO)c2n1Cc1ccc(-c2ccccc2C#N)cc1.[N-]=[N+]=[N-]>>CCCCc1nc2cccc(CO)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US06127360,1,Cc1ccc(O)c2c1NC(=O)CC2.ClCCCN1CCN(Cc2ccc3ccccc3n2)CC1>>Cc1ccc(OCCCN2CCN(Cc3ccc4ccccc4n3)CC2)c2c1NC(=O)CC2 -US04550107,1,CN(C)C1CCNCC1.O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21>>CN(C)C1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 -US20120295915A1,3,Brc1ccc2occc2c1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccc3occc3c2)cc1 -US06258955B1,7,OCCc1ccccn1>>OCCC1CCCCN1 -US04663409,2,C=CC(=O)Cl.O=C(O)C1CCNCC1>>C=CC(=O)N1CCC(C(=O)O)CC1 -US05618839,6,COC(=O)c1ccc(C(C)(C)Oc2ccc3c(c2)C(c2ccccc2)=CC3)cc1>>CC(C)(Oc1ccc2c(c1)C(c1ccccc1)=CC2)c1ccc(C(=O)O)cc1 -US20040209897A1,1,C1COCCN1.O=Cc1cc(F)c(F)c(F)c1>>O=Cc1cc(F)c(N2CCOCC2)c(F)c1 -US06403534B1,6,COC(=O)C1(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)CC1>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(OC3(C(=O)O)CC3)c(Cl)cc2F)c1=O -US08129376B2,2,Clc1cccc(OC2CCNCC2)c1.O=C(O)CNC(=O)c1cc(-c2ccccc2)[nH]n1>>O=C(NCC(=O)N1CCC(Oc2cccc(Cl)c2)CC1)c1cc(-c2ccccc2)[nH]n1 -US05834471,3,COc1ccc(NC(=O)c2csc(Br)c2OC)cc1N1CCN(C)CC1.OB(O)c1ccncc1>>COc1ccc(NC(=O)c2csc(-c3ccncc3)c2OC)cc1N1CCN(C)CC1 -US20140073634A1,1,CC(C)(O)c1cccc(CBr)c1.CC(C)Oc1ccc(-c2nc(-c3ccc(=O)[nH]c3)no2)cc1>>CC(C)Oc1ccc(-c2nc(-c3ccc(=O)n(Cc4cccc(C(C)(C)O)c4)c3)no2)cc1 -US04206142,2,CC(=N)N.O=S(=O)(Cl)C=Cc1ccc(Cl)c(Cl)c1>>CC(=N)NS(=O)(=O)C=Cc1ccc(Cl)c(Cl)c1 -US20020193402A1,1,CI.OCCn1nnc([C@@H]2C[C@@]3(c4ccccc4)[C@H](OCc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC[C@@H]2N3Cc2ccccc2)n1>>COCCn1nnc([C@@H]2C[C@@]3(c4ccccc4)[C@H](OCc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC[C@@H]2N3Cc2ccccc2)n1 -US04666915,6,CCOC(=O)c1cnc(Nc2cccc(C(F)(F)F)c2)[nH]c1=O>>O=C(O)c1cnc(Nc2cccc(C(F)(F)F)c2)[nH]c1=O -US04535161,1,C=C1CCc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.CN1CCNCC1>>C=C1CCc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 -US04179441,2,N#CCN.O=C(Cl)c1ccco1>>N#CCNC(=O)c1ccco1 -US08026257B2,6,CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(N(C)C)cc2cn[nH]c12>>CC(OCC1(c2ccc(F)cc2)CCNCC1)c1cc(N(C)C)cc2cn[nH]c12 -US08828986B2,6,CCc1cc(N2CCCN(C(=O)OC(C)(C)C)CC2)cc2[s+]c3cc(N4CCOCC4)cc(C)c3nc12>>CCc1cc(N2CCCNCC2)cc2[s+]c3cc(N4CCOCC4)cc(C)c3nc12 -US20100267709A1,6,CC(C)(C)[Si](C)(C)OC1CCC(Nc2ncc(C#N)c3[nH]c4ccc(F)cc4c23)CC1F>>N#Cc1cnc(NC2CCC(O)C(F)C2)c2c1[nH]c1ccc(F)cc12 -US20070254881A1,4,CCOC(=O)C(=O)CC(=O)c1ccc(C)cn1.Cc1ccc(NN)cn1>>CCOC(=O)c1cc(-c2ccc(C)cn2)n(-c2ccc(C)nc2)n1 -US20110301140A1,2,CN1CCCc2cc(CN)ccc21.Cc1cncc(-c2cnc(-n3ccc(C)n3)c(C(=O)O)c2)c1>>Cc1cncc(-c2cnc(-n3ccc(C)n3)c(C(=O)NCc3ccc4c(c3)CCCN4C)c2)c1 -US06329407B1,4,NC(=S)c1ccccc1.O=C1c2cc(Br)ccc2CCC1Br>>Brc1ccc2c(c1)-c1nc(-c3ccccc3)sc1CC2 -US08633223B2,1,CC1(C)COC(C(C)(C)c2ccc(CCCl)cc2)=N1.CCOCCn1c(C2CCNCC2)nc2ccccc21>>CCOCCn1c(C2CCN(CCc3ccc(C(C)(C)C4=NC(C)(C)CO4)cc3)CC2)nc2ccccc21 -US07163954B2,3,OB(O)c1cc2ccccc2s1.Oc1ccc2cc(Br)ccc2c1Cl>>Oc1ccc2cc(-c3cc4ccccc4s3)ccc2c1Cl -US04420327,4,Nc1ccc(Cl)c(OC2CCCC2=O)c1.O=C1OC(=O)C2=C1CCCC2>>O=C1CCCC1Oc1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl -US20120283297A1,2,CC(=O)OC(C)=O.N#Cc1cccc2[nH]ncc12>>CC(=O)n1ncc2c(C#N)cccc21 -US20100168418A1,1,COc1ccc2ncc(=O)n(CCN3CCC(N)CC3)c2c1.O=Cc1cc2c(cc1Br)OCCO2>>COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc5c(cc4Br)OCCO5)CC3)c2c1 -US20080221161A1,1,COc1ccc2cc(C=O)c(OC)nc2c1.NCCc1ccc(Br)cc1>>COc1ccc2cc(CNCCc3ccc(Br)cc3)c(OC)nc2c1 -US04151280,6,CCOC(=O)c1cc2c(=O)n(C)c3ccccc3n2c1>>Cn1c(=O)c2cc(C(=O)O)cn2c2ccccc21 -US06242439B1,2,CC(C)(C)[C@@H]1CC(=O)N1.CC[C@@H](N=C=O)c1ccccc1>>CC[C@@H](NC(=O)N1C(=O)C[C@H]1C(C)(C)C)c1ccccc1 -US20130324576A1,2,Cc1nn(C)c(C)c1S(=O)(=O)Cl.Fc1cc(Cl)ccc1OC1CCNCC1>>Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2F)CC1 -US20150175601A1,1,C=CC(=O)Nc1cccc(-c2cccc3cnc(Cl)nc23)c1.CN1CCC(Nc2ccc(N)cc2)CC1>>C=CC(=O)Nc1cccc(-c2cccc3cnc(Nc4ccc(NC5CCN(C)CC5)cc4)nc23)c1 -US04725600,2,CC(=O)OC(C)=O.COc1ccc(C2=CC(=Nc3c(C)cc(C)cc3C)N(C)CN2)cc1OC>>COc1ccc(C2=CC(=Nc3c(C)cc(C)cc3C)N(C)CN2C(C)=O)cc1OC -US07649009B2,1,CC(C)(C)OC(=O)NN.COC(=O)c1ccc(C=O)cc1>>COC(=O)c1ccc(/C=N/NC(=O)OC(C)(C)C)cc1 -US20090029994A1,6,FC(F)(F)c1cc(CN(Cc2cc(C(F)(F)F)ccc2-c2ccccc2OCc2ccccc2)c2ncc(N3CCOCC3)cn2)cc(C(F)(F)F)c1>>Oc1ccccc1-c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(N2CCOCC2)cn1 -US04626542,1,C1=Cc2ccccc2C(C2CCNCC2)c2ccccc21.CC(C)=O>>CC(C)N1CCC(C2c3ccccc3C=Cc3ccccc32)CC1 -US20140155477A1,2,CCc1cccc(CC)c1S(=O)(=O)Cl.Cc1c(N)cc(C(F)(F)F)cc1C(F)(F)F>>CCc1cccc(CC)c1S(=O)(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1C -US20110294780A1,1,CC(C)=O.O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CCNC[C@H]1F>>CC(C)N1CC[C@@H](N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)[C@H](F)C1 -US07838543B2,3,CN(C)CCN(C)c1nc2ccc(NC(=O)c3ccc(I)cc3)cc2s1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc(C(=O)Nc3ccc4nc(N(C)CCN(C)C)sc4c3)cc2)cc1 -US09120749B2,1,CN(C)CCc1ccc(N)cc1.O=C(c1cnc2ccc(Br)cc2c1Cl)C1CC1>>CN(C)CCc1ccc(Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)cc1 -US07229987B2,1,CN(C)CCCCl.Oc1ccc(-c2nnc(CSCc3cccc4ccccc34)o2)cc1>>CN(C)CCCOc1ccc(-c2nnc(CSCc3cccc4ccccc34)o2)cc1 -US20050101063A1,3,C#C[Si](C)(C)C.Nc1ccc(Br)cc1>>C[Si](C)(C)C#Cc1ccc(N)cc1 -US08022223B2,4,NC(=S)Nc1ncc(Br)cc1Oc1ccc(F)cc1.O=C(CBr)CCc1ccccc1>>Fc1ccc(Oc2cc(Br)cnc2Nc2nc(CCc3ccccc3)cs2)cc1 -US07678818B2,6,COC(=O)c1cc(Cl)ccc1NC(C)C>>CC(C)Nc1ccc(Cl)cc1C(=O)O -US05128448,2,O=C(O)CCc1cc2ccccc2s1.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(CCc1cc2ccccc2s1)N1C(=O)OC[C@@H]1Cc1ccccc1 -US07786109B2,1,CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCNC2=O)CC1.CCBr>>CCN1CCn2c(cc3cc(OC4CCN(C(C)C)CC4)ccc32)C1=O -US04861785,2,CCOC(=O)N1CCC(N=C=S)CC1.CNc1ccccc1>>CCOC(=O)N1CCC(NC(=S)N(C)c2ccccc2)CC1 -US04139617,7,C[C@H]1CC(=O)CC2=CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]3[C@]21CO>>C[C@H]1C[C@H](O)CC2=CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]3[C@]21CO -US20060211698A1,7,COC(=O)c1ccc2c(C3CCCCC3)c(-c3cc([N+](=O)[O-])c4nc(-c5sc(C)nc5C)ccc4c3)n(CC(=O)N3CCOCC3)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cc(N)c4nc(-c5sc(C)nc5C)ccc4c3)n(CC(=O)N3CCOCC3)c2c1 -US05631401,3,CC(=O)Cl.c1ccc2c(c1)oc1ccccc12>>CC(=O)c1ccc2oc3ccccc3c2c1 -US20070117785A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COC(Cc1ccc(Cl)cc1N)OC>>COC(Cc1ccc(Cl)cc1NC1CCN(C(=O)OC(C)(C)C)CC1)OC -US07105567B2,2,CC(C)c1cccc(C(C)C)c1N=C=O.COc1ccc(CNc2ccc(C(C)C)cc2)c(OC)c1>>COc1ccc(CN(C(=O)Nc2c(C(C)C)cccc2C(C)C)c2ccc(C(C)C)cc2)c(OC)c1 -US20140243315A1,1,CCCCNc1ncc2[nH]cc(C3CCC(O[Si](C)(C)C(C)(C)C)CC3)c2n1.Ic1ccc(CN2CCOCC2)cc1>>CCCCNc1ncc2c(n1)c(C1CCC(O[Si](C)(C)C(C)(C)C)CC1)cn2-c1ccc(CN2CCOCC2)cc1 -US04977153,6,O=C(CCCNC(=O)OCc1ccccc1)Nc1ccc2[nH]ccc2c1>>NCCCC(=O)Nc1ccc2[nH]ccc2c1 -US20070275965A1,2,CN(CCN)C1CCCCC1.O=C(CCl)OC(=O)CCl>>CN(CCNC(=O)CCl)C1CCCCC1 -US09018382B2,3,CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Br)cc2c1c(C)nn2C(C)C.CN(C)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(-c2ccc(CN(C)C)cc2)cc2c1c(C)nn2C(C)C -US20130196964A1,7,Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccnc(C2=CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccnc(C2CCN(C(=O)OC(C)(C)C)CC2)c1 -US20140249104A1,7,COC(=O)C[C@](CF)(N[S@](=O)C(C)(C)C)c1cc(Br)ccc1F>>CC(C)(C)[S@@](=O)N[C@@](CF)(CCO)c1cc(Br)ccc1F -US20100113502A1,1,COC(=O)c1ccc2c(c1)c1c(n2C)CCNC1.O=C1CCOCC1>>COC(=O)c1ccc2c(c1)c1c(n2C)CCN(C2CCOCC2)C1 -US20140275076A1,9,O=C1Cc2cc(C(=O)CCl)ccc2N1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(=O)c1ccc2c(c1)CC(=O)N2 -US20060154974A1,6,COC(=O)c1ccc(C(=O)Nc2nccs2)cc1>>O=C(O)c1ccc(C(=O)Nc2nccs2)cc1 -US06013654,1,Cc1cccn2cc(CCl)nc12.Clc1ccc(N2CCNCC2)c(Cl)c1>>Cc1cccn2cc(CN3CCN(c4ccc(Cl)cc4Cl)CC3)nc12 -USRE045183E1,1,CC1CCC(N(C(=O)Nc2ncc(Br)s2)C2CCCC2)CC1.CCOC(=O)c1c[nH]c(S)n1>>CCOC(=O)c1c[nH]c(Sc2cnc(NC(=O)N(C3CCCC3)C3CCC(C)CC3)s2)n1 -US20110065702A1,3,O=C1Cc2cc(Br)cnc2N1.O=Cc1ccc2c(/C=C/c3ccncc3)n[nH]c2c1>>O=C1Nc2ncc(Br)cc2C1=Cc1ccc2c(/C=C/c3ccncc3)n[nH]c2c1 -US20050209284A1,3,O=C(O)c1ccc(Br)s1.OB(O)c1cccc2cccnc12>>O=C(O)c1ccc(-c2cccc3cccnc23)s1 -US06489320B1,9,BrC(Br)(Br)Br.O=Cc1ccco1>>BrC(Br)=Cc1ccco1 -US20150238558A1,1,COC(=O)c1ccc(CBr)cc1.C[C@@H](N)c1ccccc1F>>COC(=O)c1ccc(CN[C@H](C)c2ccccc2F)cc1 -US20090324581A1,6,COC(=O)C(O)CNCC(=O)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21>>O=C(O)C(O)CNCC(=O)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21 -US06486155B1,2,CC(=O)Cl.COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccccc2c(=O)n1N>>COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccccc2c(=O)n1NC(C)=O -US20110071149A1,1,C1COCCN1.O=C(CCl)Nc1cccc(-c2cnc3ccccc3n2)c1>>O=C(CN1CCOCC1)Nc1cccc(-c2cnc3ccccc3n2)c1 -US04814340,1,CC(C)(CCCc1cccc(Oc2ccccc2)c1)c1ccc(O)cc1.CC(C)Br>>CC(C)Oc1ccc(C(C)(C)CCCc2cccc(Oc3ccccc3)c2)cc1 -US20110269734A1,1,Cc1cc(OCC[C@@H](C)C2CCNCC2)ccc1C(=O)O.Clc1cnc(Cl)nc1>>Cc1cc(OCC[C@@H](C)C2CCN(c3ncc(Cl)cn3)CC2)ccc1C(=O)O -US20110034469A1,6,CC(C)(C)OC(=O)N1C[C@H]2CCCN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21>>O=C(N[C@@H]1CCOc2ccccc21)[C@@H]1CN2CCC[C@@H]2CN1 -US20110021493A1,2,CC(C)N(C)C/C=C/C(=O)O.Fc1ccc(Nc2ncnc3oc4c(c23)CCNC4)cc1Cl>>CC(C)N(C)C/C=C/C(=O)N1CCc2c(oc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1 -US05674886,1,ClCc1ccc(Cl)cc1.N#Cc1ccc(Nn2cncn2)cc1>>N#Cc1ccc(N(Cc2ccc(Cl)cc2)n2cncn2)cc1 -US06169107A,1,CC(C)(C)OC(=O)NCc1ccc(CCl)cc1.CCOC(=O)c1cc2c(Cl)ccc(O)c2n1C>>CCOC(=O)c1cc2c(Cl)ccc(OCc3ccc(CNC(=O)OC(C)(C)C)cc3)c2n1C -US06627651B1,6,COC(=O)C1=Cc2cc(OCc3ccc(-c4ccccc4)cc3)ccc2CCC1>>O=C(O)C1=Cc2cc(OCc3ccc(-c4ccccc4)cc3)ccc2CCC1 -US05932571,1,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3[nH]2)CC1.ClCc1ccco1>>CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3n2Cc2ccco2)CC1 -US20090215754A1,1,CCCCNc1cc(C(=O)O)cc(S(N)(=O)=O)c1Oc1ccccc1.CN(C)CCCCl>>CCCCNc1cc(C(=O)OCCCN(C)C)cc(S(N)(=O)=O)c1Oc1ccccc1 -US05602127,4,CCCc1nc2c(C)cc(-c3nc4ccccc4[nH]3)cc2n1Cc1ccc(-c2ccccc2C#N)cc1.[N-]=[N+]=[N-]>>CCCc1nc2c(C)cc(-c3nc4ccccc4[nH]3)cc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 -US20090143592A1,7,COC(=O)c1cccc(S(C)(=O)=O)c1>>CS(=O)(=O)c1cccc(CO)c1 -US20110082133A1,10,Cc1c(C2CC2)cc(Cl)c(=O)n1CCc1ccc(C(=O)OC(C)(C)C)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1ccc(CCn2c(CBr)c(C3CC3)cc(Cl)c2=O)cc1 -US04810799,2,O=C([O-])COC(=O)Nc1cc(Cl)cc(Cl)c1>>O=C1COC(=O)N1c1cc(Cl)cc(Cl)c1 -US05889056,6,CC(C)(C)OC(=O)NC(CS(=O)(=O)CCNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC(CS(=O)(=O)CCN)C(=O)OC(C)(C)C -US20150284408A1,1,CC(C)(C)OC(=O)NC1CCN(CCOS(C)(=O)=O)CC1.COc1ccc2ncc(=O)[nH]c2c1>>COc1ccc2ncc(=O)n(CCN3CCC(NC(=O)OC(C)(C)C)CC3)c2c1 -US07910592B2,9,BrC(Br)(Br)Br.OCc1cc2c(cc1I)CCC2>>BrCc1cc2c(cc1I)CCC2 -US07071358B2,1,CNc1ccc(Br)cc1C.COc1ccc(CCl)cc1>>COc1ccc(CN(C)c2ccc(Br)cc2C)cc1 -US20050256121A1,7,N#Cc1ccc2ncsc2c1>>NCc1ccc2ncsc2c1 -US08426453B2,3,COC(=O)c1sc(Br)c(Br)c1F.N#Cc1cc(B(O)O)ccc1OCc1ccccc1>>COC(=O)c1sc(-c2ccc(OCc3ccccc3)c(C#N)c2)c(Br)c1F -US06251900B1,1,Clc1cc(Cl)nc(Cl)n1.c1ccc2[nH]cnc2c1>>Clc1cc(Cl)nc(-n2cnc3ccccc32)n1 -US20110201609A1,7,COc1ccccc1NS(=O)(=O)c1ccc([N+](=O)[O-])cc1>>COc1ccccc1NS(=O)(=O)c1ccc(N)cc1 -US20110224202A1,3,COc1cc(I)cc(OC)c1Br.OB(O)c1cccs1>>COc1cc(-c2cccs2)cc(OC)c1Br -US20100331293A1,1,CC1(C)CNCCO1.O=[N+]([O-])c1cc(Cl)cnc1N1CCOCC1>>CC1(C)CN(c2cnc(N3CCOCC3)c([N+](=O)[O-])c2)CCO1 -US20150018422A1,1,CC(C)(C)CO.CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)c(O)c2)c1)C1CC1>>CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)c(OCC(C)(C)C)c2)c1)C1CC1 -US07842713B2,6,COC(=O)c1cc(Oc2ccc(C(=O)OC(C)(C)C)c(F)c2)c2c(c1)OC(C)(C)C2>>CC(C)(C)OC(=O)c1ccc(Oc2cc(C(=O)O)cc3c2CC(C)(C)O3)cc1F -US04554276,3,N#CCCCCCBr.c1ccccc1>>N#CCCCCCc1ccccc1 -US20110312934A1,6,Cc1nc2ccc(N3CC4CN(Cc5ccccc5)CC4C3)nn2c1-c1ccnc(CN)c1>>Cc1nc2ccc(N3CC4CNCC4C3)nn2c1-c1ccnc(CN)c1 -US20020052322A1,2,COC(=O)[C@@H](N)Cc1cccs1.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>COC(=O)[C@H](Cc1cccs1)NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1 -US05348976,2,CC(C)OC(=O)N[C@H](C(=O)O)C(C)C.CC(N)c1cc2cc(F)ccc2o1>>CC(C)OC(=O)N[C@H](C(=O)NC(C)c1cc2cc(F)ccc2o1)C(C)C -US20120190677A1,2,Cc1ccc(N2CCOCC2)cc1C1CC(C)(C)c2cc(C(=O)O)ccc2N1.NS(=O)(=O)C1CC1>>Cc1ccc(N2CCOCC2)cc1C1CC(C)(C)c2cc(C(=O)NS(=O)(=O)C3CC3)ccc2N1 -US08012964B2,1,BrCCCCBr.CCCCOc1nc(N)c2nc(OC)[nH]c2n1>>CCCCOc1nc(N)c2nc(OC)n(CCCCBr)c2n1 -US20140171404A1,2,CNCCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1.O=C(O)c1noc(=O)[nH]1>>CN(CCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)C(=O)c1noc(=O)[nH]1 -US20120158127A1,7,COC(=O)COCCOc1ccc([N+](=O)[O-])cc1>>COC(=O)COCCOc1ccc(N)cc1 -US20100216788A1,6,COC(=O)C(C)(C)NC(=O)c1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1>>CC(C)(NC(=O)c1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1)C(=O)O -US20150225449A1,7,C[C@H](Nc1cc(C#N)ccc1[N+](=O)[O-])[C@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@H](Nc1cc(C#N)ccc1N)[C@H](NC(=O)OC(C)(C)C)C(=O)O -US08962638B2,6,C[C@@H]1CCN(Cc2ccccc2)C[C@@H]1N(C)c1ncnc2[nH]ccc12>>C[C@@H]1CCNC[C@@H]1N(C)c1ncnc2[nH]ccc12 -US05061703,3,BrC12CC3CC(CC(C3)C1)C2.c1ccccc1>>c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 -US08084611B2,6,CC[C@@H]1C[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccc(N3CCOCC3)cn2)c2cc(C(F)(F)F)ccc2N1C(=O)OCC(C)(C)C(=O)OC(C)(C)C>>CC[C@@H]1C[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccc(N3CCOCC3)cn2)c2cc(C(F)(F)F)ccc2N1C(=O)OCC(C)(C)C(=O)O -US04935548,7,CCOC(=O)C1=C(C)NC(C=O)=C(C(=O)OCC)C1c1ccccc1/C=C/C(=O)OC(C)(C)C>>CCOC(=O)C1=C(C)NC(CO)=C(C(=O)OCC)C1c1ccccc1/C=C/C(=O)OC(C)(C)C -US20060287365A1,8,CSC1(c2c(C#N)nn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)c2N)CC1(F)F.O=C(OO)c1cccc(Cl)c1>>CS(=O)C1(c2c(C#N)nn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)c2N)CC1(F)F -US05763489,7,COC(=O)C1CCc2c(OC)cccc2C1=O>>COC(=O)[C@H]1CCc2c(OC)cccc2[C@@H]1O -US20110190280A1,6,CC(C)(C)OC(=O)N1CC[C@@H](Oc2ccc([N+](=O)[O-])cn2)C1>>O=[N+]([O-])c1ccc(O[C@@H]2CCNC2)nc1 -US20050136444A1,1,COc1ccc(C=O)cc1Cl.N=C(N)NN>>COc1ccc(C=NNC(=N)N)cc1Cl -US20110112127A1,6,COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(-c4cnn(C5CCN(C(=O)OC(C)(C)C)CC5)c4)cc23)c(F)n1>>COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(-c4cnn(C5CCNCC5)c4)cc23)c(F)n1 -US04829069,1,CN(C)c1ccccc1CCl.Sc1ncnc2ccccc12>>CN(C)c1ccccc1CSc1ncnc2ccccc12 -US20140163012A1,6,CC(C)(C)OC(=O)N1CCc2oc3cc(-n4ccc(OCc5ccc(C(F)(F)F)nn5)cc4=O)ccc3c2C1>>O=c1cc(OCc2ccc(C(F)(F)F)nn2)ccn1-c1ccc2c3c(oc2c1)CCNC3 -US07838543B2,7,CN(C)CCN(C)c1nc2ccc([N+](=O)[O-])cc2s1>>CN(C)CCN(C)c1nc2ccc(N)cc2s1 -US05324744,6,CC1(C)CC(C)(C)c2ccc(C(=O)Oc3ccc(C(=O)OCc4ccccc4)cc3)cc2O1>>CC1(C)CC(C)(C)c2ccc(C(=O)Oc3ccc(C(=O)O)cc3)cc2O1 -US20010039279A1,1,C=O.CC(C)(C)OC(=O)NC[C@@H]1CNC[C@H]1CNC(=O)OC(C)(C)C>>CN1C[C@@H](CNC(=O)OC(C)(C)C)[C@H](CNC(=O)OC(C)(C)C)C1 -US05208240,2,CCCn1c(=O)c2nc(C(CC)c3ccc(NCC(=O)O)cc3)[nH]c2n(CCC)c1=O.CO>>CCCn1c(=O)c2nc(C(CC)c3ccc(NCC(=O)OC)cc3)[nH]c2n(CCC)c1=O -US20110015157A1,9,C[C@@H](c1ccc(-c2ccc(F)cc2)cc1)N1CC[C@](CCC(N)=O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2ccc(F)cc2)cc1)N1CC[C@](CCC#N)(c2ccccc2)OC1=O -US04748256,9,COc1ccc2cc(C3(C(C)Br)OCC(C)(C)CO3)ccc2c1Br>>COc1ccc2cc(C3(C(C)Br)OCC(C)(C)CO3)ccc2c1 -US20110275797A1,6,CN(CCN1CCOCC1)c1ccc(OCc2ccccc2)c(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)OC(C)(C)C)c1>>CN(CCN1CCOCC1)c1ccc(O)c(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)OC(C)(C)C)c1 -US20100173824A1,2,CCOC(=O)C1=CNCCc2c1[nH]c1cc(OC)ccc21.O=C(Cl)c1ccccc1>>CCOC(=O)C1=CN(C(=O)c2ccccc2)CCc2c1[nH]c1cc(OC)ccc21 -US20070287715A1,3,CCOC(=O)c1cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2[nH]1.N#Cc1ccc(I)cc1>>CCOC(=O)c1cc2cc(-c3ccc(C#N)cc3)ccc2[nH]1 -US05034417,1,CC(=O)c1ccc(NS(C)(=O)=O)c(Sc2ccc(F)cc2F)c1.[NH4+]>>CC(N)c1ccc(NS(C)(=O)=O)c(Sc2ccc(F)cc2F)c1 -US20130345192A1,1,CC(C)(C)OC(=O)N1CCC[C@H](O)C1.C[Si](C)(C)CCOCn1ccc2c(Cl)ncnc21>>CC(C)(C)OC(=O)N1CCC[C@H](Oc2ncnc3c2ccn3COCC[Si](C)(C)C)C1 -US06861418B2,3,Cc1[nH]c(C=O)c(C)c1C(=O)N1CCN(C)CC1.O=C1Cc2c(cccc2-c2cccc(C(F)(F)F)c2)N1>>Cc1[nH]c(C=C2C(=O)Nc3cccc(-c4cccc(C(F)(F)F)c4)c32)c(C)c1C(=O)N1CCN(C)CC1 -US20150246922A1,3,Cc1cc(Br)c2c(c1)cc1n2CCNC1=O.OB(O)c1ccc(F)c(F)c1>>Cc1cc(-c2ccc(F)c(F)c2)c2c(c1)cc1n2CCNC1=O -US05155113,2,CCCCCCCCCC(=O)Cl.O=c1cc(O)cc[nH]1>>CCCCCCCCCC(=O)Oc1cc[nH]c(=O)c1 -US20140275030A1,2,CC(=O)Cl.Cc1noc(C)c1-c1cc(CN)c2[nH]c(=O)n3c2c1OC[C@@H]3c1ccccn1>>CC(=O)NCc1cc(-c2c(C)noc2C)c2c3c1[nH]c(=O)n3[C@@H](c1ccccn1)CO2 -US09029531B2,6,CCOC(=O)Cc1ccc(NS(C)(=O)=O)cc1>>CS(=O)(=O)Nc1ccc(CC(=O)O)cc1 -US07897601B2,6,CC(C)(C)OC(=O)N(CC=Cc1ccc(Cl)cc1)Cc1ccc(F)c(F)c1>>Fc1ccc(CNCC=Cc2ccc(Cl)cc2)cc1F -US04638070,3,CC1CSc2ccccc2C1.CCC(=O)Cl>>CCC(=O)c1ccc2c(c1)CC(C)CS2 -US08853408B2,1,CC(C)(C)OC(=O)c1ccc(CN2CCC(C=O)CC2)cc1.N[C@@H]1C[C@H]1c1ccccc1>>CC(C)(C)OC(=O)c1ccc(CN2CCC(CN[C@@H]3C[C@H]3c3ccccc3)CC2)cc1 -US04326055,2,C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C.C1COCCN1>>C/C(=C\c1ccc(C(=O)N2CCOCC2)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C -US20120142771A1,1,CI.COC(=O)C(O)c1ccccc1-c1ccccc1>>COC(=O)C(OC)c1ccccc1-c1ccccc1 -US06677331B2,2,CS(=O)(=O)Cl.NCc1ncn2ccsc12>>CS(=O)(=O)NCc1ncn2ccsc12 -US20130184249A1,2,CN[C@H]1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)C[C@@H]1c1ccc(Cl)c(Cl)c1.O=C(Cl)OC1CCCC1>>CN(C(=O)OC1CCCC1)[C@H]1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)C[C@@H]1c1ccc(Cl)c(Cl)c1 -US04377695,6,COC(=O)CCCCCCCn1c(=O)oc2ccccc21>>O=C(O)CCCCCCCn1c(=O)oc2ccccc21 -US20140112945A1,6,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](NC(=O)OC(C)(C)C)C4CCCCC4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)C4CCCCC4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US07968578B2,6,COC(=O)c1cccc2ccn(-c3cccc(Cl)c3)c12>>O=C(O)c1cccc2ccn(-c3cccc(Cl)c3)c12 -US20090082367A1,3,CC(C)(c1cccs1)c1nnc(C2CC2)n1C1CC1.CN(C)C=O>>CC(C)(c1ccc(C=O)s1)c1nnc(C2CC2)n1C1CC1 -US05382670,6,CC(=O)N1C(C(=O)c2cn(C(=O)OC(C)(C)C)c3ccccc23)CSC1c1cccnc1>>CC(=O)N1C(C(=O)c2c[nH]c3ccccc23)CSC1c1cccnc1 -US07211572B2,2,Cn1cc(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(C(=O)O)c(OC(=O)c2ccccc2)c1=O.NCc1cccc(Cl)c1>>Cn1cc(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(C(=O)NCc2cccc(Cl)c2)c(OC(=O)c2ccccc2)c1=O -US08153658B2,1,COC(=O)c1ccc2oc(Cl)nc2c1.C[C@H](c1cccc2ccccc12)N(CC1CCNCC1c1cccc(F)c1)C(=O)OC(C)(C)C>>COC(=O)c1ccc2oc(N3CCC(CN(C(=O)OC(C)(C)C)[C@H](C)c4cccc5ccccc45)C(c4cccc(F)c4)C3)nc2c1 -US20090197860A1,1,Brc1cncc(Br)c1.CC(C)(C)OC(=O)N1C[C@H]2NCC[C@H]2C1>>CC(C)(C)OC(=O)N1C[C@@H]2[C@@H](CCN2c2cncc(Br)c2)C1 -US04837305,1,ClCC1CO1.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(OCC2CO2)cc1 -US20150158846A1,2,C=CC(=O)Cl.C[C@H](N)COc1cccc(Nc2cc(Br)cn(C)c2=O)n1>>C=CC(=O)N[C@@H](C)COc1cccc(Nc2cc(Br)cn(C)c2=O)n1 -US20140121198A1,2,CN(C)C(=O)Cl.C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@@H]1CC[C@@H](CN)CC1>>C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@@H]1CC[C@@H](CNC(=O)N(C)C)CC1 -US06410573B1,2,COc1ccc(Cl)cc1C(=O)O.NCCc1ccc(Br)cc1>>COc1ccc(Cl)cc1C(=O)NCCc1ccc(Br)cc1 -US20150224071A1,1,CCCCCC12CCC(CO)(CC1)CC2.CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(F)cc1F>>CCCCCC12CCC(COc3cc(F)c(C(=O)NS(=O)(=O)N(C)C)cc3Cl)(CC1)CC2 -US20100292212A1,1,CC(C)(C)CC(=O)N1CCC2(CCNC2=O)CC1.OC(c1ccc(Br)cc1)C(F)F>>CC(C)(C)CC(=O)N1CCC2(CC1)CCN(c1ccc(C(O)C(F)F)cc1)C2=O -US07790733B2,1,CC(=O)c1cccc(O)c1N.CI>>COc1cccc(C(C)=O)c1N -US07638648B2,6,C=Cc1c(C)c(C#Cc2ccc(CC(=O)OC)cc2)cc(C(C)(C)C)c1OC(C)C>>C=Cc1c(C)c(C#Cc2ccc(CC(=O)O)cc2)cc(C(C)(C)C)c1OC(C)C -US20120149691A1,7,NC(=O)c1cnn2cc([N+](=O)[O-])cc2c1Nc1ccccc1>>NC(=O)c1cnn2cc(N)cc2c1Nc1ccccc1 -US08691822B2,2,CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)O)c4c3OCC4)nc2N1C1CCCC1.CN1CCN(C[C@H](O)CN)CC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC[C@@H](O)CN4CCN(C)CC4)c4c3OCC4)nc2N1C1CCCC1 -US20050222410A1,3,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(Cl)nc1.OB(O)c1ccoc1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2ccoc2)nc1 -US08680108B2,1,Brc1ncnc2[nH]cnc12.CC(N)c1cc(Cl)c2cnn(C)c2c1-c1cc(F)cc(F)c1>>CC(Nc1ncnc2[nH]cnc12)c1cc(Cl)c2cnn(C)c2c1-c1cc(F)cc(F)c1 -US20130316938A1,3,CC(CC=O)CC(C)(C)C.CC(c1ccc2ccccc2c1)[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=CCC(C)CC(C)(C)C)c1ccc2ccccc2c1 -US08754114B2,2,COCC(=O)Cl.O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CCNCC5)c4)cnn23)c1>>COCC(=O)N1CCC(n2cc(-c3cnn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CC1 -US08987307B2,2,Cc1ccccc1-c1ccncc1NCC#N.O=C(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ccccc1-c1ccncc1N(CC#N)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1cc(Br)c2ccccc2c1C=O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(Br)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US20100308754A1,2,C=C(C)C(=O)O.Nc1ccc(C=Cc2ccc(C=Cc3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1>>C=C(C)C(=O)Nc1ccc(C=Cc2ccc(C=Cc3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1 -US04143039,2,CC1(C)S[C@@H]2C(N)C(=O)N2C1c1nnn[nH]1.NCc1ccccc1SCC(=O)O>>CC1(C)S[C@@H]2C(NC(=O)CSc3ccccc3CN)C(=O)N2C1c1nnn[nH]1 -US04444584,1,CCOC(=O)C(C)Oc1ccc(O)cc1.Fc1ccc2nc(Cl)ccc2c1>>CCOC(=O)C(C)Oc1ccc(Oc2ccc3cc(F)ccc3n2)cc1 -US05932601,8,COc1cc(/C=C/CO)cc(OC)c1OCc1ccccc1>>COc1cc(C=CC=O)cc(OC)c1OCc1ccccc1 -US20090306139A1,4,CC(C)(C)C(=O)CBr.N#CC1CCN(C(=O)N2CC(C(N)=S)CC(c3ccc(OC(F)(F)F)cc3)C2)CC1>>CC(C)(C)c1csc(C2CC(c3ccc(OC(F)(F)F)cc3)CN(C(=O)N3CCC(C#N)CC3)C2)n1 -US05981537,1,Nc1cc(Cl)nc(Cl)n1.OCc1cccc2ccccc12>>Nc1cc(Cl)nc(OCc2cccc3ccccc23)n1 -US20050148643A1,4,C[C@@H](O)C(=O)O.Nc1ccccc1N>>C[C@H](O)c1nc2ccccc2[nH]1 -US05866577,6,COC(=O)C(Cc1cc2ccc(C#N)cc2[nH]1)c1ccc(O[C@H]2CCN(C(=O)OC(C)(C)C)C2)cc1>>CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(C(Cc3cc4ccc(C#N)cc4[nH]3)C(=O)O)cc2)C1 -US20110224204A1,3,O=S(=O)(Oc1ccc(F)cc1-c1ccc(OCc2ccc3ccccc3n2)cc1)C(F)(F)F.OB(O)c1ccncc1>>Fc1ccc(-c2ccncc2)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1 -US06825170B2,3,Brc1cnc(I)nc1.OC/C=C/c1ccc(B(O)O)cc1>>OC/C=C/c1ccc(-c2ncc(Br)cn2)cc1 -US20080039440A1,1,Nc1nc(Cl)cc(Cl)n1.O=C(Nc1cccc(C(F)(F)F)c1)N1CCCCc2cc(O)ccc21>>Nc1nc(Cl)cc(Oc2ccc3c(c2)CCCCN3C(=O)Nc2cccc(C(F)(F)F)c2)n1 -US20100216750A1,7,O=C(CCl)c1ncc(-c2ccccn2)o1>>OC(CCl)c1ncc(-c2ccccn2)o1 -US20100234351A1,1,COC(=O)CCCNCc1ccc(OC)cc1.O=Cc1c(Cl)ncnc1Nc1ccc(Oc2cccc(Cl)c2)c(Cl)c1>>COC(=O)CCCN(Cc1ccc(OC)cc1)c1ncnc(Nc2ccc(Oc3cccc(Cl)c3)c(Cl)c2)c1C=O -US20150018546A1,7,Cc1ncnc2c1c(NCc1ccc([N+](=O)[O-])cc1)cc(=O)n2OCc1ccccc1>>Cc1ncnc2c1c(NCc1ccc(N)cc1)cc(=O)n2OCc1ccccc1 -US05635518,1,BrCCCCOc1ccccc1.CCOC(=O)[C@@H]1CCCNC1>>CCOC(=O)[C@@H]1CCCN(CCCCOc2ccccc2)C1 -US05614351,2,O=C=NC(=O)C(Cl)(Cl)Cl.Oc1ccccc1>>O=C(NC(=O)C(Cl)(Cl)Cl)Oc1ccccc1 -US08063099B2,2,Cc1nc(C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c(-c2cccc(Cl)c2)s1.O=C(O)c1cccc2c1OCCO2>>Cc1nc(C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2cccc3c2OCCO3)c(-c2cccc(Cl)c2)s1 -US20100022529A1,1,CCOC(=O)c1c(C)cc(C)[nH]c1=O.OB(O)c1ccc(F)cc1>>CCOC(=O)c1c(C)cc(C)n(-c2ccc(F)cc2)c1=O -US20070213364A1,1,CCOC(=O)CCc1ccc(OCc2ccc(CCl)cc2)cc1F.Fc1ccc(-c2cc(CCc3ccccc3)[nH]n2)cc1>>CCOC(=O)CCc1ccc(OCc2ccc(Cn3nc(-c4ccc(F)cc4)cc3CCc3ccccc3)cc2)cc1F -US04528028,6,COC(=O)CC[C@@H](CF)NC(=O)COc1ccc(Cl)cc1Cl>>O=C(O)CC[C@@H](CF)NC(=O)COc1ccc(Cl)cc1Cl -US08669271B2,1,CC(C)(C)OC(=O)N1CCC(C(O)Cc2nc(-c3ccc(S(C)(=O)=O)cc3)ncc2Cl)CC1>>CC(C)(C)OC(=O)N1CCC(C2Cc3nc(-c4ccc(S(C)(=O)=O)cc4)ncc3O2)CC1 -US05403859,1,CI.COC1(c2cccc(OCc3ccc4ccccc4c3)c2)CCOCC1O>>COC1COCCC1(OC)c1cccc(OCc2ccc3ccccc3c2)c1 -US06514996B2,2,CO.COc1ccc(C(=O)O)c2ccoc12>>COC(=O)c1ccc(OC)c2occc12 -US20150165063A1,6,CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COc2cc3c(c4ccccc24)[C@H](CCl)CN3C(=O)OC(C)(C)C)cc1>>CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COc2cc3c(c4ccccc24)[C@H](CCl)CN3)cc1 -US06897231B2,6,N#Cc1ccc2c(c1)c(-c1cccnc1)nn2C1CCCCO1>>N#Cc1ccc2[nH]nc(-c3cccnc3)c2c1 -US20080171737A1,1,CN.O=S1(=O)[C@H](CCCO)Oc2ccccc2N1c1ccccc1>>CNCCC[C@@H]1Oc2ccccc2N(c2ccccc2)S1(=O)=O -US07605168B2,3,COc1ccc(B(O)O)cc1OC.Clc1ccnc2[nH]ccc12>>COc1ccc(-c2ccnc3[nH]ccc23)cc1OC -US20080015222A1,1,COc1cc(O)cc([N+](=O)[O-])c1.OC1CCOC1>>COc1cc(OC2CCOC2)cc([N+](=O)[O-])c1 -US08569317B2,7,C#CCOc1ccc([N+](=O)[O-])c(C(=O)c2ccc(C(C)C)cc2)c1>>C#CCOc1ccc(N)c(C(=O)c2ccc(C(C)C)cc2)c1 -US20140249104A1,3,C#CC1CC1.NC1=N[C@](CF)(c2cc(NC(=O)c3ccc(Br)cn3)ccc2F)C[C@@H](C(F)(F)F)O1>>NC1=N[C@](CF)(c2cc(NC(=O)c3ccc(C#CC4CC4)cn3)ccc2F)C[C@@H](C(F)(F)F)O1 -US20110178068A1,1,CCCCCCCCCCCCC(C)(C)C(=O)O.ClCCl>>CCCCCCCCCCCCC(C)(C)C(=O)OCCl -US08324216B2,2,CN(C)Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O.COc1cc(N2CCNCC2)ccc1Cl>>COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3CN(C)C)CC2)ccc1Cl -US20140315856A1,1,CS(N)(=O)=O.Cc1ccc(S(=O)(=O)n2c(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)cc3ccc(I)cc32)cc1>>Cc1ccc(S(=O)(=O)n2c(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)cc3ccc(NS(C)(=O)=O)cc32)cc1 -US07276526B2,6,COc1cc(Cl)c(-c2nc(C3(c4ccccc4OCc4ccccc4)CC3)sc2C)cc1C>>COc1cc(Cl)c(-c2nc(C3(c4ccccc4O)CC3)sc2C)cc1C -US05753664,1,CN(C)CCCCl.Cc1cccc2nc(SCc3ccc(C(=O)c4ccc(O)cc4)cc3)n(C)c(=O)c12>>Cc1cccc2nc(SCc3ccc(C(=O)c4ccc(OCCCN(C)C)cc4)cc3)n(C)c(=O)c12 -US07241785B2,7,CCOC(=O)/C=C/c1cn(-c2ccccc2)nc1OCc1ccccc1>>CCOC(=O)CCc1cn(-c2ccccc2)nc1OCc1ccccc1 -US04169144,2,COc1ccc(C(=O)O)c(OC)c1OC.OCCN1CCNCC1>>COc1ccc(C(=O)OCCN2CCNCC2)c(OC)c1OC -US20110092461A1,2,CC1CN(S(=O)(=O)c2ccc(C(=O)O)cc2)CC(C)O1.Nc1ccc(Cl)c(-c2ccccn2)c1>>CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cc2)CC(C)O1 -US07915443B2,2,CCN(CC)CCN.Cc1cc(C(=O)Nc2cccc(C#Cc3cncc(C(=O)N=S(C)(=O)c4cccc(C(=O)O)c4)c3)c2)n(C)n1>>CCN(CC)CCNC(=O)c1cccc(S(C)(=O)=NC(=O)c2cncc(C#Cc3cccc(NC(=O)c4cc(C)nn4C)c3)c2)c1 -US20110118236A1,2,C1CCNC1.CCc1nn(Cc2ccc(C(=O)O)cc2)c2c1CCCC2>>CCc1nn(Cc2ccc(C(=O)N3CCCC3)cc2)c2c1CCCC2 -US20100016297A1,7,O=C1COc2c(cc(Cl)cc2[N+](=O)[O-])N1>>Nc1cc(Cl)cc2c1OCC(=O)N2 -US20120178744A1,6,CCOC(=O)C1(C)CCC2(CC1)OCCO2>>CCOC(=O)C1(C)CCC(=O)CC1 -US20100331293A1,3,CCCC[Sn](C#N)(CCCC)CCCC.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(Cl)cc(N2CCOCC2)c1>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(C#N)cc(N2CCOCC2)c1 -US08436002B2,6,CCc1cn(CCN2CCCC2)c(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>CCc1cn(CCN2CCCC2)c(C2CCNCC2)n1 -US20100240638A1,6,CN1CCN(c2ncc3c(n2)CN(C(=O)OC(C)(C)C)C3)CC1>>CN1CCN(c2ncc3c(n2)CNC3)CC1 -US08309542B2,2,COC1CN(C(=O)OC(C)(C)C)CC1N.O=C(Cl)c1ccc(Cl)s1>>COC1CN(C(=O)OC(C)(C)C)CC1NC(=O)c1ccc(Cl)s1 -US20020068734A1,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1nnc(Cl)c2ccccc12>>CC(C)(C)OC(=O)N1CCN(c2nnc(Cl)c3ccccc23)CC1 -US07271262B2,1,BrCC1CC1.Clc1ncnc2[nH]ccc12>>Clc1ncnc2c1ccn2CC1CC1 -US20090048263A1,1,Brc1cc(-c2ccccc2)ccn1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2cc(-c3ccccc3)ccn2)CC1 -US20130143843A1,3,C#C[Mg+].CON(C)C(=O)C1(C)CC(c2ccc(C)cc2)=C(C#N)C(=O)N1>>C#CC(=O)C1(C)CC(c2ccc(C)cc2)=C(C#N)C(=O)N1 -US20070167447A1,4,COC(=O)c1ccc(N)c(I)c1.C[Si](C)(C)C#CC1CCCCC1>>COC(=O)c1ccc2[nH]c([Si](C)(C)C)c(C3CCCCC3)c2c1 -US20100004297A1,6,CCN(CC(O)c1ccccc1)c1ccc(C(O[Si](CC)(CC)CC)(C(F)(F)F)C(F)(F)F)cc1>>CCN(CC(O)c1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 -US07884126B2,2,CC(C)(C)OC(=O)c1ccc(-c2ccc3[nH]nc(N)c3c2)o1.O=C(Cl)c1ccc(Cl)s1>>CC(C)(C)OC(=O)c1ccc(-c2ccc3[nH]nc(NC(=O)c4ccc(Cl)s4)c3c2)o1 -US06218128B1,6,CCOC(=O)c1ccc2cc(-c3ccc4c(c3)C(c3ccc(C)cc3)=CCC4(C)C)ccc2c1>>Cc1ccc(C2=CCC(C)(C)c3ccc(-c4ccc5cc(C(=O)O)ccc5c4)cc32)cc1 -US08227500B2,1,Clc1cc(I)ccn1.N#Cc1c[nH]cc1-c1ccccc1>>N#Cc1cn(-c2ccnc(Cl)c2)cc1-c1ccccc1 -US20150210697A1,7,COc1ccc(CN2CCOC[C@H]2COc2cc(C#N)cc([N+](=O)[O-])c2Cl)c(OC)c1>>COc1ccc(CN2CCOC[C@H]2COc2cc(C#N)cc(N)c2Cl)c(OC)c1 -US20060047123A1,2,CC(=O)SCC(=O)NCCCCCN.O=C(Cl)c1ccccc1>>CC(=O)SCC(=O)NCCCCCNC(=O)c1ccccc1 -US08592444B2,6,COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CCN(CCc3ccccc3)CC1)O2>>O=C(O)/C=C/c1ccc2c(c1)C(=O)CC1(CCN(CCc3ccccc3)CC1)O2 -US04314065,1,CCOC(=O)C(C)Br.CN(c1ccc(O)cc1)c1nc2ccc(Br)cc2o1>>CCOC(=O)C(C)Oc1ccc(N(C)c2nc3ccc(Br)cc3o2)cc1 -US20070037846A1,1,CC(C)CBr.Cc1cc(C=O)ccc1O>>Cc1cc(C=O)ccc1OCC(C)C -US04002673,7,COC(=O)C=Cc1cccc([N+](=O)[O-])c1>>COC(=O)C=Cc1cccc(N)c1 -US20120004228A1,2,COC(=O)c1cc(N)cc(C(=O)c2ccc(N(C)c3ccc(Cl)cc3)cc2)c1.O=C(Cl)c1ccc(Cl)cc1Cl>>COC(=O)c1cc(NC(=O)c2ccc(Cl)cc2Cl)cc(C(=O)c2ccc(N(C)c3ccc(Cl)cc3)cc2)c1 -US05849911,2,CC(C)(C)OC(=O)NN(Cc1ccc(-c2nnn(C(C)(C)c3ccccc3)n2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1.CC[C@H](C)[C@H](NC(=O)OC)C(=O)O>>CC[C@H](C)[C@H](NC(=O)OC)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(-c2nnn(C(C)(C)c3ccccc3)n2)cc1)NC(=O)OC(C)(C)C -US20080188528A1,2,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(CC(=O)N(c2ccccc2)c2ccccc2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(CC(=O)N(c3ccccc3)c3ccccc3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2 -US08415376B2,7,CS(=O)(=O)Nc1cc(-c2ccc3nccc(C4=CCOCC4)c3c2)cnc1Cl>>CS(=O)(=O)Nc1cc(-c2ccc3nccc(C4CCOCC4)c3c2)cnc1Cl -US20100069367A1,6,CCOC(=O)c1cn(-c2ccc(Br)cc2Cl)c(-c2ccccc2Cl)n1>>O=C(O)c1cn(-c2ccc(Br)cc2Cl)c(-c2ccccc2Cl)n1 -US04140775,1,CCc1cccc(N2CCNCC2)c1.O=[N+]([O-])c1ccc(CCl)cc1>>CCc1cccc(N2CCN(Cc3ccc([N+](=O)[O-])cc3)CC2)c1 -US08828991B2,6,COC(=O)c1cc2ncn(-c3ccc(N4CCCN(C)CC4)cc3)c(=O)c2s1>>CN1CCCN(c2ccc(-n3cnc4cc(C(=O)O)sc4c3=O)cc2)CC1 -US08487108B2,7,CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCC#N)c2cc(F)cc(Cl)c2)C1>>CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCCN)c2cc(F)cc(Cl)c2)C1 -US20100016396A1,1,COC(=O)[C@H](C)Oc1cc(Oc2c(C=O)c(C)nn2C)c(Cl)cc1Cl.NN>>COC(=O)[C@H](C)Oc1cc(Oc2c(/C=N/N)c(C)nn2C)c(Cl)cc1Cl -US09133148B2,3,Cc1ccccc1B(O)O.Cc1nc(CN2CCN(C(=O)OC(C)(C)C)CC2)ccc1Br>>Cc1ccccc1-c1ccc(CN2CCN(C(=O)OC(C)(C)C)CC2)nc1C -US20120289501A1,1,Clc1ncnc2[nH]cc(I)c12.OC1CCC2(CC1)OCCO2>>Clc1ncnc2c1c(I)cn2C1CCC2(CC1)OCCO2 -US20100081700A1,6,COC(=O)[C@@H]1C[C@@]2(c3ccc(-c4ccccc4)cc3)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CCCCCC=CCS2>>CC(C)(C)OC(=O)N[C@H]1CCCCCC=CCS[C@@]2(c3ccc(-c4ccccc4)cc3)C[C@@H](C(=O)O)N(C2)C1=O -US07494997B2,2,Cc1ccc(N)cc1Nc1nccc(-c2cccnc2)n1.O=C(Cl)c1ccc(CN2CCOCC2)c(Br)c1>>Cc1ccc(NC(=O)c2ccc(CN3CCOCC3)c(Br)c2)cc1Nc1nccc(-c2cccnc2)n1 -US20140364605A1,1,Brc1ccc2c(c1)[nH]c1ccccc12.Brc1ccccn1>>Brc1ccc2c3ccccc3n(-c3ccccn3)c2c1 -US05843957,6,CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCCN(CC)Cc3ccccc3)c2)c2cccnc21>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCCNCC)c2)c2cccnc21 -US08436041B2,6,CCOC(=O)C1CCN(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2sc3ccccc3c2C)CC1>>Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)N2CCC(C(=O)O)CC2)sc2ccccc12 -US04584293,7,COc1cc2c(cc1OC)CC(=O)N(CCCN(C)C1CCc3cc(OC)c(OC)cc3C1)C=C2>>COc1cc2c(cc1OC)CCN(CCCN(C)C1CCc3cc(OC)c(OC)cc3C1)C=C2 -US08415368B2,2,O=Cc1c[nH]c(-c2ccccc2)c1.O=S(=O)(Cl)c1cccnc1Cl>>O=Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cccnc2Cl)c1 -US20130005760A1,3,Cc1cc(=O)c2ccc(Br)cc2n1-c1cc(NC(=O)OC(C)(C)C)c(F)cc1F.Cc1noc(C)c1B1OC(C)(C)C(C)(C)O1>>Cc1noc(C)c1-c1ccc2c(=O)cc(C)n(-c3cc(NC(=O)OC(C)(C)C)c(F)cc3F)c2c1 -US20130237571A1,1,CCCC(CC(=O)OC)c1ccc(O)cc1.CO/N=C(\COc1ccc(CO)cc1)c1ccccc1>>CCCC(CC(=O)OC)c1ccc(OCc2ccc(OC/C(=N\OC)c3ccccc3)cc2)cc1 -US20150126485A1,3,Cc1ncc(B2OC(C)(C)C(C)(C)O2)s1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1>>Cc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N2CC[C@@H](O)C2)s1 -US08399681B2,2,CC(=O)OC(C)=O.N[C@@H]1C[C@H](CO)N(C2=NC(=O)C(=Cc3ccc4c(cnn4Cc4ccc(C(F)(F)F)cc4C(F)(F)F)c3)S2)C1>>CC(=O)N[C@@H]1C[C@H](CO)N(C2=NC(=O)C(=Cc3ccc4c(cnn4Cc4ccc(C(F)(F)F)cc4C(F)(F)F)c3)S2)C1 -US04518603,1,Nc1ccccc1C(=O)c1cccc(F)c1.O=[N+]([O-])c1cccnc1Cl>>O=C(c1cccc(F)c1)c1ccccc1Nc1ncccc1[N+](=O)[O-] -US04806151,2,CCCO.O=C(O)c1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1>>CCCOC(=O)c1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1 -US07704994B2,1,CC(C)(C)OC(=O)N1CCc2cc(O)c(I)cc2CC1.CNC(=O)c1ccc(Cl)nc1>>CNC(=O)c1ccc(Oc2cc3c(cc2I)CCN(C(=O)OC(C)(C)C)CC3)nc1 -US20140100231A1,10,Cc1cc(C(F)(F)F)c(=O)[nH]n1.O=C1CCC(=O)N1Br>>O=c1[nH]nc(CBr)cc1C(F)(F)F -US20040259904A1,4,C=CCOc1ccc2c(c1)Cc1c(-c3ccc(C#N)cc3)n[nH]c1-2.[N-]=[N+]=[N-]>>C=CCOc1ccc2c(c1)Cc1c(-c3ccc(-c4nnn[nH]4)cc3)n[nH]c1-2 -US07939533B2,7,OCc1ncccc1O>>OCC1NCCCC1O -US04673746,3,COc1cccc(Cl)c1Cl.O=C(Cl)c1c(F)cccc1F>>COc1ccc(C(=O)c2c(F)cccc2F)c(Cl)c1Cl -US20110178060A1,2,CCCN=C=O.CN(C(=O)N(C)[C@@H]1CNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCCNC(=O)N1C[C@@H](c2ccc(F)cc2)[C@H](N(C)C(=O)N(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1 -US20140343032A1,2,O=C1CC2COCC1N2.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=C1CC2COCC1N2S(=O)(=O)c1ccccc1[N+](=O)[O-] -US08362248B2,1,CO.O=[N+]([O-])c1ccnc(Cl)c1O>>COc1c([N+](=O)[O-])ccnc1Cl -US20040122057A1,3,COC(C(=O)NCc1ccc(C#N)cc1)c1ccc(Br)cc1F.COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc(C(OC)C(=O)NCc3ccc(C#N)cc3)c(F)c2)cc1 -US20080085886A1,7,CCOC(=O)c1cncc2c(Nc3ccc(I)cc3F)c(C(=O)N(C)C)oc12>>CN(C)C(=O)c1oc2c(CO)cncc2c1Nc1ccc(I)cc1F -US20140364433A1,1,Cc1nc(C(=O)N2CCCC(C)C2CN)c(-c2ccc(F)cc2)s1.FC(F)(F)c1ccc(Cl)nc1>>Cc1nc(C(=O)N2CCC[C@H](C)[C@@H]2CNc2ccc(C(F)(F)F)cn2)c(-c2ccc(F)cc2)s1 -US06384278B1,2,CCOC(=O)CCCCCCC(=O)O.Nc1cc(Cl)ccc1O>>O=C(O)CCCCCCC(=O)Nc1cc(Cl)ccc1O -US20120220590A1,1,C=CCOc1cccc(Oc2ccc(CNc3cccc([N+](=O)[O-])c3C)cc2)c1.N#Cc1ccc(CBr)cc1>>C=CCOc1cccc(Oc2ccc(CN(Cc3ccc(C#N)cc3)c3cccc([N+](=O)[O-])c3C)cc2)c1 -US08765730B2,9,Cc1cc(C(=O)C[C@H](c2ccc(C3CN(C(=O)OC(C)(C)C)C3)cc2)c2ccccc2C)ccn1.NO>>Cc1cc(/C(C[C@H](c2ccc(C3CN(C(=O)OC(C)(C)C)C3)cc2)c2ccccc2C)=N/O)ccn1 -US04590201,3,Cc1ccc(C(=O)Cl)cc1.Clc1ccccc1>>Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1 -US06169095A,1,Cc1ccc2cccc(O)c2n1.Clc1cccc(Cl)c1CBr>>Cc1ccc2cccc(OCc3c(Cl)cccc3Cl)c2n1 -US20110263584A1,3,C[C@@H](c1ccc(Br)cc1)N1CC[C@](CC2(O)CC2)(c2ccc(F)cc2)OC1=O.Cc1cc(B(O)O)ccn1>>Cc1cc(-c2ccc([C@H](C)N3CC[C@](CC4(O)CC4)(c4ccc(F)cc4)OC3=O)cc2)ccn1 -US20080318925A1,3,CCCCNC(=O)c1nnc2c(Br)cccc2c1N.COc1ncc(B2OC(C)(C)C(C)(C)O2)c(OC)n1>>CCCCNC(=O)c1nnc2c(-c3cnc(OC)nc3OC)cccc2c1N -US07078369B2,1,CC(C)=O.COC(=O)c1c(N)cccc1S(=O)(=O)NC(C)(C)C>>COC(=O)c1c(NC(C)C)cccc1S(=O)(=O)NC(C)(C)C -US20100029628A1,2,CCOC(=O)[C@@H]1C[C@H](c2ccc(OC)cc2)[C@@H](O)CN1.O=C(Cl)OCc1ccccc1>>CCOC(=O)[C@@H]1C[C@H](c2ccc(OC)cc2)[C@@H](O)CN1C(=O)OCc1ccccc1 -US20110034507A1,6,CCOC(=O)c1cccc(-c2cc3cc(OCc4ccccc4)ccc3n2C(=O)OC(C)(C)C)c1>>CCOC(=O)c1cccc(-c2cc3cc(O)ccc3n2C(=O)OC(C)(C)C)c1 -US05155249,7,C[Si](C)(C)c1cc([N+](=O)[O-])cc([Si](C)(C)C)c1>>C[Si](C)(C)c1cc(N)cc([Si](C)(C)C)c1 -US20050222186A1,3,Brc1cnc(NCc2ccncc2)nc1NC1CCN(Cc2ccccc2)CC1.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2cnc(NCc3ccncc3)nc2NC2CCN(Cc3ccccc3)CC2)cc1 -US20040209913A1,6,CCCC1CC(=O)C(Cl)=C(NC(Cc2ccc3c(c2)CCN3C(=O)c2c(Cl)cncc2Cl)C(=O)OC)C1>>CCCC1CC(=O)C(Cl)=C(NC(Cc2ccc3c(c2)CCN3C(=O)c2c(Cl)cncc2Cl)C(=O)O)C1 -US20050137263A1,1,C[Si](C)(C)C#Cc1ccc(N)c(F)c1.O=C(O)c1ccc(F)c(F)c1F>>C[Si](C)(C)C#Cc1ccc(Nc2c(C(=O)O)ccc(F)c2F)c(F)c1 -US05637256,1,CCCCCC[C@@H](C)O.Cc1ccc(O)cc1[N+](=O)[O-]>>CCCCCC[C@H](C)Oc1ccc(C)c([N+](=O)[O-])c1 -US20060178400A1,1,Fc1ccc(Br)cn1.Oc1ccc(Oc2ccccc2)cc1>>Brc1ccc(Oc2ccc(Oc3ccccc3)cc2)nc1 -US20110190276A1,2,CCOC(=O)C1(C(=O)OCC)CCCN1.O=C(Br)CBr>>CCOC(=O)C1(C(=O)OCC)CCCN1C(=O)CBr -US04762925,1,O=C(CCl)Nc1cc(O)ccc1O>>O=C1COc2ccc(O)cc2N1 -US05204365,7,COC(=O)C(C)c1cccc(C(=O)c2ccccc2)c1>>COC(=O)C(C)c1cccc(C(O)c2ccccc2)c1 -US04918206,6,COC(=O)c1cc2cc(S(=O)(=O)N(C)C)c(Cl)c(Cl)c2o1>>CN(C)S(=O)(=O)c1cc2cc(C(=O)O)oc2c(Cl)c1Cl -US20080103132A1,1,Clc1ccc(-c2nn(Cc3ccccc3)c3c2CCNCC3)cc1.NC(=O)CBr>>NC(=O)CN1CCc2c(-c3ccc(Cl)cc3)nn(Cc3ccccc3)c2CC1 -US20070149508A1,2,COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1.O=S(=O)(Cl)c1ccc(Br)cc1>>COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1ccc(Br)cc1 -US07550597B2,1,C1COCCN1.COc1cc2ncc(NC3CCCCC3)nc2cc1Br>>COc1cc2ncc(NC3CCCCC3)nc2cc1N1CCOCC1 -US07776897B2,3,Cn1c(-c2ccccc2Cl)nnc1C(C)(C)C=O.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>Cn1c(-c2ccccc2Cl)nnc1C(C)(C)/C=C/c1ccccc1 -US20150094297A1,6,CC(C)(C)[S@@](=O)NC1(c2nc(CO[Si](C)(C)C(C)(C)C)cs2)CCOCC1>>CC(C)(C)[S@@](=O)NC1(c2nc(CO)cs2)CCOCC1 -US07951824B2,2,CCOC(=O)c1cc(-c2cncc(F)c2)cc(C)n1.Nc1ccc(F)cc1>>Cc1cc(-c2cncc(F)c2)cc(C(=O)Nc2ccc(F)cc2)n1 -US05440049,1,CCNCc1cccc(O)c1.ClC=CCCl>>CCN(C/C=C/Cl)Cc1cccc(O)c1 -US20140249139A1,2,CC(=O)Cl.COc1ccc(-c2ccc3ncnc(-c4cccc(C(=O)N5CCNC(C)(C)C5)c4)c3c2)cn1>>COc1ccc(-c2ccc3ncnc(-c4cccc(C(=O)N5CCN(C(C)=O)C(C)(C)C5)c4)c3c2)cn1 -US20080091031A1,1,CI.Oc1c(Br)cc(S(F)(F)(F)(F)F)cc1Br>>COc1c(Br)cc(S(F)(F)(F)(F)F)cc1Br -US07897607B2,3,CB(O)O.Cc1cc(C)c(-c2cccc3c2c(=O)c(Br)cn3Cc2ccccc2)c(C)c1>>Cc1cc(C)c(-c2cccc3c2c(=O)c(C)cn3Cc2ccccc2)c(C)c1 -US20040266764A1,3,CC(C)(C)OC(=O)N1CCN(c2ccc(Br)cn2)CC1.OB(O)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3ccc(F)cc3)cn2)CC1 -US20100016319A1,1,C1COCCN1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2cc(Cl)nc(C)n2)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2cc(N3CCOCC3)nc(C)n2)cc1 -US08507690B2,7,CC(=O)Nc1nc(C=Cc2ccc(C(=O)O)c(F)c2)cs1>>CC(=O)Nc1nc(CCc2ccc(C(=O)O)c(F)c2)cs1 -US04665181,7,CN(C)CCCn1ncc2cc(/C=C/c3ccc(O)cc3)ccc2c1=O>>CN(C)CCCn1ncc2cc(CCc3ccc(O)cc3)ccc2c1=O -US07728142B2,1,Cc1nc2ccc(I)cc2c(Cl)c1S(C)(=O)=O.O[C@H]1CCCNC1>>Cc1nc2ccc(I)cc2c(N2CCC[C@H](O)C2)c1S(C)(=O)=O -US20060116410A1,2,CNC(=O)COc1cc(C#N)ccc1CN.Cc1cc(C(=O)O)n(C)n1>>CNC(=O)COc1cc(C#N)ccc1CNC(=O)c1cc(C)nn1C -US08815896B2,7,CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(N)c2[N+](=O)[O-])c2ccccc12>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(N)c2N)c2ccccc12 -US05728835,2,CC(=O)OC(C)=O.COc1cccc(N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)C(=O)c2ccc(N)c(OC)c2)c1>>COc1cccc(N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)C(=O)c2ccc(NC(C)=O)c(OC)c2)c1 -US20090203657A1,2,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)O)n1.NCc1ccc(F)c(Br)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(F)c(Br)c2)n1 -US06358948B1,3,CC1(C)Nc2ccc(Br)cc2C(C)(C)O1.N#Cc1cc(F)cc(Br)c1>>CC1(C)Nc2ccc(-c3cc(F)cc(C#N)c3)cc2C(C)(C)O1 -US07635715B2,6,CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2c(F)cccc2C(C)(C)C1=O>>CC1(C)C(=O)C(C(=O)NCC(=O)O)=C(O)c2c(F)cccc21 -US20110105490A1,9,COc1cc(Br)c(CN2C(=O)c3ccccc3C2=O)cc1OC.N#C[Cu]>>COc1cc(C#N)c(CN2C(=O)c3ccccc3C2=O)cc1OC -US20140155407A1,3,O=Cc1ccc(-c2ccsc2)nc1.[Mg+]C1CC1>>OC(c1ccc(-c2ccsc2)nc1)C1CC1 -US05118827,1,C=COCC.CC(=CCCC(C)=CCCC(C)=CC=C(C(C)C)C(O)C#N)CCl>>CCOC(C)OC(C#N)C(=CC=C(C)CCC=C(C)CCC=C(C)CCl)C(C)C -US04804684,2,NCCBr.O=C(Cl)OCc1ccccc1>>O=C(NCCBr)OCc1ccccc1 -US07087778B2,1,CC(=O)C(=O)O.Nc1ccc(F)c(F)c1F>>CC(Nc1ccc(F)c(F)c1F)C(=O)O -US20150183775A1,1,COC(=O)c1ccc(F)cc1F.Oc1cnc(Cl)c(F)c1>>COC(=O)c1ccc(F)cc1Oc1cnc(Cl)c(F)c1 -US07351841B2,7,CCOC(=O)c1csc(-c2ccc(C(C)(C)C)cc2)c1OCOC>>COCOc1c(CO)csc1-c1ccc(C(C)(C)C)cc1 -US20110142856A1,6,CC(C)(C)OC(=O)NCCCCN(Cc1ccc(C(=O)N(Cc2nccn2COCC[Si](C)(C)C)Cc2nccn2COCC[Si](C)(C)C)cc1)C(=O)OCc1ccccc1>>C[Si](C)(C)CCOCn1ccnc1CN(Cc1nccn1COCC[Si](C)(C)C)C(=O)c1ccc(CN(CCCCN)C(=O)OCc2ccccc2)cc1 -US20120208798A1,2,CC(=O)OC(C)=O.Cc1cn(-c2ccc3c(c2)C(NC(=O)OC(C)(C)C)CC(C)N3)cn1>>CC(=O)N1c2ccc(-n3cnc(C)c3)cc2[C@H](NC(=O)OC(C)(C)C)C[C@@H]1C -US20110124636A1,2,Cn1cc(C(=O)O)c2ccccc21.NC[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)c1nc(N)sc1-c1cccc(F)c1>>Cn1cc(C(=O)NC[C@@H]2C[C@@H]3C[C@@H]3N2C(=O)c2nc(N)sc2-c2cccc(F)c2)c2ccccc21 -US20120316327A1,9,BrC(Br)(Br)Br.C[C@]1(F)[C@H](O)O[C@H](COC(=O)c2ccc(Cl)cc2)[C@H]1OC(=O)c1ccc(Cl)cc1>>C[C@@]1(F)[C@H](OC(=O)c2ccc(Cl)cc2)[C@@H](COC(=O)c2ccc(Cl)cc2)O[C@@H]1Br -US20120309789A1,1,CCOC1CCC(=O)CC1.Cc1cc2[nH]c(=O)n(C3CCNCC3)c2cc1C>>CCO[C@@H]1CC[C@@H](N2CCC(n3c(=O)[nH]c4cc(C)c(C)cc43)CC2)CC1 -US20150111870A1,1,C[O-].FC1(F)CCC(Cc2c(Cl)nc3ccc(Br)cc3c2Cl)CC1>>COc1nc2ccc(Br)cc2c(Cl)c1CC1CCC(F)(F)CC1 -US20090182029A1,2,Nc1ccccc1N.O=C(O)CCCCCCCNC(=O)c1cccc(C=C2C(=O)Nc3ccc(F)cc32)c1>>Nc1ccccc1NC(=O)CCCCCCCNC(=O)c1cccc(C=C2C(=O)Nc3ccc(F)cc32)c1 -US20040214888A1,9,COC(=O)Cc1cccc(-c2ccc(OC)c(C(C)=O)c2)c1.NO>>COC(=O)Cc1cccc(-c2ccc(OC)c(C(C)=NO)c2)c1 -US20080139576A1,2,CCCCCN.COc1ccc(CN2C(=O)CN(c3cccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)c3)S2(=O)=O)cc1>>CCCCCNC(=O)[C@H](Cc1cccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)c1)NC(=O)OC(C)(C)C -US20090182140A1,1,Clc1nc(Cl)c2ccccc2n1.NS(=O)(=O)c1ccc(Cl)cc1Cl>>O=S(=O)(Nc1nc(Cl)nc2ccccc12)c1ccc(Cl)cc1Cl -US05672615,6,COC(=O)C1(N(Cc2ccccc2)S(=O)(=O)c2ccc(OC)cc2)CCN(Cc2ccccc2)CC1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)C2(C(=O)O)CCN(Cc3ccccc3)CC2)cc1 -US20140371199A1,3,CC(=O)Nc1cc(Br)ccc1C(=O)N1CCC(N(C)C(=O)OC(C)(C)C)CC1.CC1(C)OB(c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)OC1(C)C>>CC(=O)Nc1cc(-c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)ccc1C(=O)N1CCC(N(C)C(=O)OC(C)(C)C)CC1 -US20120190677A1,2,CS(N)(=O)=O.Cc1ccc(N2CCOCC2)cc1C1CC(C)(C)c2cc(C(=O)O)ccc2N1>>Cc1ccc(N2CCOCC2)cc1C1CC(C)(C)c2cc(C(=O)NS(C)(=O)=O)ccc2N1 -US07217697B2,7,O=C(O)c1ccccc1Oc1ccccc1>>OCc1ccccc1Oc1ccccc1 -US20150239838A1,6,CC(C)(C)OC(=O)Cn1nc(C(N)=O)c2ccccc21>>NC(=O)c1nn(CC(=O)O)c2ccccc12 -US07312241B2,3,CCOP(=O)(CC#N)OCC.COc1cccc(C(=O)c2cc(OC)cc(OC)c2)c1>>COc1cccc(C(=CC#N)c2cc(OC)cc(OC)c2)c1 -US20040204417A1,1,CCCC(=O)c1c(F)cccc1F.NCc1ccccc1>>CCCC(=O)c1c(F)cccc1NCc1ccccc1 -US04523021,1,ClCc1ccc(Cl)c(Cl)c1.O=C1CC2(C(=O)N1)C(=O)Nc1ccccc12>>O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Cl)c(Cl)c1)c1ccccc12 -US20130165440A1,6,CC(C)(C)OC(=O)N1CC=C(c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)CC1>>O=[N+]([O-])c1cc(C2=CCNCC2)cc(C(F)(F)F)c1 -US05310918,4,CSc1ccc(C#N)cc1.[N-]=[N+]=[N-]>>CSc1ccc(-c2nnn[nH]2)cc1 -US20150183784A1,3,CS(=O)(=O)Cc1ncc(Oc2ccc(F)cc2F)c(Cl)n1.Cn1cc(B2OC(C)(C)C(C)(C)O2)c2ccccc2c1=O>>Cn1cc(-c2nc(CS(C)(=O)=O)ncc2Oc2ccc(F)cc2F)c2ccccc2c1=O -US07932274B2,1,Brc1cccc(Br)n1.CNC>>CN(C)c1cccc(Br)n1 -US20080176926A1,8,Cc1cc(CO)cc(C)c1CCC(=O)O>>Cc1cc(C=O)cc(C)c1CCC(=O)O -US20110172097A1,7,CC(C)(C)C(=O)C(CCCC(C)(C)c1ccccc1)n1cncn1>>CC(C)(CCCC(C(O)C(C)(C)C)n1cncn1)c1ccccc1 -US20100094041A1,3,C=Cc1cc(OC)c(CCC)c(OC)c1.Fc1cccc(F)c1Br>>CCCc1c(OC)cc(C=Cc2c(F)cccc2F)cc1OC -US20110190227A1,1,CCOC(=O)Cc1cccc(Oc2ccc(Br)cc2CBr)c1.Oc1ccccc1>>CCOC(=O)Cc1cccc(Oc2ccc(Br)cc2COc2ccccc2)c1 -US07632844B2,2,COc1ccc(C2CC(OC(C)=O)CCC2N)cc1OC.O=C(Cl)c1ccc(OCC2CC2)c(OCC2CC2)c1>>COc1ccc(C2CC(OC(C)=O)CCC2NC(=O)c2ccc(OCC3CC3)c(OCC3CC3)c2)cc1OC -US20040009980A1,6,CCOC(=O)CCc1cnc(C#N)c(OC[C@H](O)CNC(C)(C)CC2Cc3ccccc3C2)c1>>CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cc(CCC(=O)O)cnc1C#N -US20130039906A1,3,Brc1cc2c(I)nn(C3CCCCO3)c2cn1.OB(O)c1ccccc1>>Brc1cc2c(-c3ccccc3)nn(C3CCCCO3)c2cn1 -US08124606B2,1,Clc1ccc(N2CCNCC2)cc1.O=C1Nc2cc(CO)cnc2N2CCSCC12>>O=C1Nc2cc(CN3CCN(c4ccc(Cl)cc4)CC3)cnc2N2CCSCC12 -US05371099,2,CCOC(=O)CC(C)=O.Nc1ccc(SC(F)(F)F)cc1>>CC(=O)CC(=O)Nc1ccc(SC(F)(F)F)cc1 -US20090239848A1,6,CC(C)(C)OC(=O)N1CCCN(C(=O)c2ccccc2Br)CC1>>O=C(c1ccccc1Br)N1CCCNCC1 -US07037935B2,7,COC(=O)C1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1>>O=C1CC(CO)CN1c1ccc(OCc2cccc(F)c2)cc1 -US20080004271A1,6,C[C@@H](COCc1ccccc1)Cc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1>>C[C@@H](CO)Cc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1 -US20120245144A1,6,Cc1nc(-c2cn3c(n2)-c2ccc(OC(C)C4CCCN(C(=O)OC(C)(C)C)CC4)cc2OCC3)n(C(C)C)n1>>Cc1nc(-c2cn3c(n2)-c2ccc(OC(C)C4CCCNCC4)cc2OCC3)n(C(C)C)n1 -US06727264B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.O=C=Nc1ccccc1[N+](=O)[O-]>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](NC(=O)Nc3ccccc3[N+](=O)[O-])c3ccccc3)CC2)c1 -US06410526B1,10,C=CC(CC(=O)OCC)c1cnc(C)nc1.O>>CCOC(=O)CC(CCO)c1cnc(C)nc1 -US20070149570A1,3,COc1ccc(-c2ccc(C#N)cc2)cc1C=O.C[Mg+]>>COc1ccc(-c2ccc(C#N)cc2)cc1C(C)O -US20140343000A1,6,C=C(C)[C@@H]1CC[C@]2(NCc3ccsc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCc3ccsc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20130116216A1,1,C=CC(=O)Nc1ccc(S(=O)(=O)N2CCC(N)CC2)cc1.O=CCc1ccccc1>>C=CC(=O)Nc1ccc(S(=O)(=O)N2CCC(NCCc3ccccc3)CC2)cc1 -US07566699B2,1,CC(=O)c1c(O)cccc1O.COC(=O)CBr>>COC(=O)COc1cccc(O)c1C(C)=O -US20080306046A1,2,CC(C)(C)OC(=O)N1CCC(CCCO)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(CCCOS(C)(=O)=O)CC1 -US20110124875A1,7,N#Cc1ccccc1S(=O)(=O)N1CCCC1>>NCc1ccccc1S(=O)(=O)N1CCCC1 -US08058441B2,2,CC(=O)N1c2ccc(N)cc2C(C)(c2ccccc2)CC1(C)C.Cc1cccc(C(=O)O)c1Br>>CC(=O)N1c2ccc(NC(=O)c3cccc(C)c3Br)cc2C(C)(c2ccccc2)CC1(C)C -US04988733,1,Cc1cccc(Br)c1.Oc1ccc(F)cc1>>Cc1cccc(Oc2ccc(F)cc2)c1 -US07101898B2,2,C/C(=C\C(=O)O)c1ccc(CC(C)C)cc1.C1CCN(C[C@@H]2CCCN2)CC1>>C/C(=C\C(=O)N1CCC[C@H]1CN1CCCCC1)c1ccc(CC(C)C)cc1 -US08962622B2,6,O=C1c2ccccc2C(=O)N1C[C@@H]1CC[C@@H](Nc2nccc(-n3nnc4ccccc43)n2)CC1>>NC[C@@H]1CC[C@@H](Nc2nccc(-n3nnc4ccccc43)n2)CC1 -US07345067B2,1,COC(=O)COc1ccc(NC(=O)OC(C)(C)C)cc1C.Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCl>>COC(=O)COc1ccc(N(Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)C(=O)OC(C)(C)C)cc1C -US07351725B2,7,COC(=O)c1ccc(-c2noc(-c3cc(-c4ccccc4)c(C(F)(F)F)s3)n2)cc1>>OCc1ccc(-c2noc(-c3cc(-c4ccccc4)c(C(F)(F)F)s3)n2)cc1 -US20090018122A1,1,CC(C)(O)CN.O=[N+]([O-])c1cnc2cc(OCc3ccccc3)ccc2c1Cl>>CC(C)(O)CNc1c([N+](=O)[O-])cnc2cc(OCc3ccccc3)ccc12 -US09040522B2,3,COCCCNC(=O)c1ccc(-n2ncc(Br)c2OC)nc1.Cc1cc(B2OC(C)(C)C(C)(C)O2)ccc1C#N>>COCCCNC(=O)c1ccc(-n2ncc(-c3ccc(C#N)c(C)c3)c2OC)nc1 -US20060041128A1,2,CCC(NCCCNC(=O)OC(C)(C)C)c1nc2onc(C)c2c(=O)n1Cc1ccccc1.Cc1ccc(C(=O)Cl)cc1>>CCC(c1nc2onc(C)c2c(=O)n1Cc1ccccc1)N(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc(C)cc1 -US09040538B2,1,CCc1cncc(CBr)c1.Cc1cc(O)nc(S)n1>>CCc1cncc(CSc2nc(C)cc(O)n2)c1 -US08933105B2,6,COc1ccc(S(=O)(=O)n2cc(CN(C)C(=O)OC(C)(C)C)cc2-c2cccnc2C#N)cn1>>CNCc1cc(-c2cccnc2C#N)n(S(=O)(=O)c2ccc(OC)nc2)c1 -US07598264B2,6,COc1c(O)nc(N(C)S(C)(=O)=O)c2c1C(=O)N(Cc1ccc(F)cc1)CC2>>CN(c1nc(O)c(O)c2c1CCN(Cc1ccc(F)cc1)C2=O)S(C)(=O)=O -US20120245169A1,3,C=C[Sn](CCCC)(CCCC)CCCC.Cc1cccc(I)c1C(=O)O>>C=Cc1cccc(C)c1C(=O)O -US07351725B2,8,CCCCCCCCOCc1ccc(CO)cc1>>CCCCCCCCOCc1ccc(C=O)cc1 -US20090209522A1,1,CCOC(=O)c1coc(Cl)n1.Cc1ccc(C(C)(C)C)cc1O>>CCOC(=O)c1coc(Oc2cc(C(C)(C)C)ccc2C)n1 -US20100105700A1,3,CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC=C(OS(=O)(=O)C(F)(F)F)[C@@]3(C)CC[C@@H]12.OB(O)c1cncc(Cl)c1>>CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC=C(c4cncc(Cl)c4)[C@@]3(C)CC[C@@H]12 -US20120142671A1,6,CC(C)(C)OC(=O)NC1(C(N)=O)CCCC1>>NC(=O)C1(N)CCCC1 -US20120022057A1,2,Brc1ccc2c(c1)CCN2.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)N1CCc2cc(Br)ccc21 -US08501732B2,3,CC[Mg+].CON(C)C(=O)c1ccc(Cl)cc1Nc1ccccc1Cl>>CCC(=O)c1ccc(Cl)cc1Nc1ccccc1Cl -US05958496,6,CSC[C@H](NC(=O)OC(C)(C)C)c1ccccc1>>CSC[C@H](N)c1ccccc1 -US20110028487A1,2,Cn1ccn2c(=O)c(OCc3ccccc3)c(C(=O)O)nc12.NCC(=O)Cc1ccc(Cl)cc1>>Cn1ccn2c(=O)c(OCc3ccccc3)c(C(=O)NCC(=O)Cc3ccc(Cl)cc3)nc12 -US06939888B2,9,COc1cc(Cl)ccc1CBr.[C-]#N>>COc1cc(Cl)ccc1CC#N -US04136200,6,CC(=O)OC(C)(CCO)c1ccccc1-c1ccccc1>>CC(O)(CCO)c1ccccc1-c1ccccc1 -US20030199440A1,1,CC(C)(C)OC(=O)CN(Cc1ccncc1)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.N=C(N)N>>CC(C)(C)OC(=O)CN(Cc1ccncc1)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1 -US09067897B2,7,CC(=O)c1ccc2c(c1)OCO2>>CC(O)c1ccc2c(c1)OCO2 -US20090264428A1,6,CC(C)(C)OC(=O)NC1(CO[Si](C)(C)C(C)(C)C)CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)NC1(CO[Si](C)(C)C(C)(C)C)CCNC1 -US07598393B2,1,CC(C)S(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1.NCC1CC1>>CC(C)S(=O)(=O)c1ccc(NCC2CC2)c([N+](=O)[O-])c1 -US06215001B1,2,NCCCn1ccnc1.O=C(O)CCOc1ccc(Cl)cc1>>O=C(CCOc1ccc(Cl)cc1)NCCCn1ccnc1 -US07342031B2,1,CSc1nsc(Cl)n1.OCc1ccsc1>>CSc1nsc(OCc2ccsc2)n1 -US07291643B2,1,CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)[nH]2)cc1.ICCCc1ccccc1>>CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2CCCc2ccccc2)cc1 -US20140248268A1,2,CC(C)(C)OC(=O)c1c(N)sc2c1CC(C)(C)OC2.S=C=Nc1ccccc1>>CC(C)(C)OC(=O)c1c(NC(=S)Nc2ccccc2)sc2c1CC(C)(C)OC2 -US04337081,2,Nc1nc(C(Cl)(Cl)Cl)ns1.O=C(Cl)CCl>>O=C(CCl)Nc1nc(C(Cl)(Cl)Cl)ns1 -US20080255114A1,7,CC(C)C[C@H]1COCC(=O)N1>>CC(C)C[C@H]1COCCN1 -US05489691,7,CC1(C)O[C@H](CC#N)C[C@H](CC(=O)N(Cc2ccccc2)Cc2ccccc2)O1>>CC1(C)O[C@H](CCN)C[C@H](CC(=O)N(Cc2ccccc2)Cc2ccccc2)O1 -US20120277208A1,7,Cn1ccc(NC(=O)c2cc(OCc3ccccc3)cc(OC3(C(=O)O)CCC3)c2)n1>>Cn1ccc(NC(=O)c2cc(OCc3ccccc3)cc(OC3(CO)CCC3)c2)n1 -US20090186876A1,2,CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F.O=C=NCCc1ccccc1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NCCc3ccccc3)CC2)nc1C(F)(F)F -US08163935B2,2,CC(=O)OC(C)=O.COC(=O)c1ccc(C(F)(F)F)cc1N>>COC(=O)c1ccc(C(F)(F)F)cc1NC(C)=O -US20150119362A1,1,CCc1nc(Cl)cc(-c2cccc(Cl)c2)n1.NC(=O)Cc1ccc(N)cc1>>CCc1nc(Nc2ccc(CC(N)=O)cc2)cc(-c2cccc(Cl)c2)n1 -US20060189636A1,6,CC(=O)O[C@H]1C[C@H](n2cnc3c(N[C@H]4CCc5ccccc54)ncnc32)O[C@@H]1CO[Si](C)(C)C(C)(C)C>>CC(=O)O[C@H]1C[C@H](n2cnc3c(N[C@H]4CCc5ccccc54)ncnc32)O[C@@H]1CO -US20070270421A1,2,CN1CC(N2CCC(N(C)C(=O)Nc3cc(Oc4ccc(N)cc4F)ncn3)CC2)C1.O=C(Cc1ccc(F)cc1)N=C=S>>CN1CC(N2CCC(N(C)C(=O)Nc3cc(Oc4ccc(NC(=S)NC(=O)Cc5ccc(F)cc5)cc4F)ncn3)CC2)C1 -US20080214612A1,6,COc1ccc2ccsc2c1>>Oc1ccc2ccsc2c1 -US20140323464A1,3,N#CCC(=O)N1CCCC(n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1.O=Cc1ccccc1Cl>>N#CC(=Cc1ccccc1Cl)C(=O)N1CCCC(n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1 -US08969345B2,1,C/C(C#N)=C1/c2ccc(CBr)cc2COc2cc(F)ccc21.CC(C)c1nc(Cl)c(Cl)[nH]1>>C/C(C#N)=C1/c2ccc(Cn3c(C(C)C)nc(Cl)c3Cl)cc2COc2cc(F)ccc21 -US20100069629A1,2,CN1CCNCC1.O=C(O)c1cc(Cl)ccn1>>CN1CCN(C(=O)c2cc(Cl)ccn2)CC1 -US06951879B2,1,C1CNC1.O=S1(=O)N=C(c2ccc(Br)cc2)c2ccc(OCCCCBr)cc21>>O=S1(=O)N=C(c2ccc(Br)cc2)c2ccc(OCCCCN3CCC3)cc21 -US20100216788A1,1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.COC(=O)c1cc(Oc2ccc(N)cc2Cl)cc(C(F)(F)F)c1>>COC(=O)c1cc(Oc2ccc(Nc3ncnc4ccn(CCNC(=O)OC(C)(C)C)c34)cc2Cl)cc(C(F)(F)F)c1 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2C(F)(F)F)CN1c1cc(C)nn1C1CCC1>>Cc1cc(N2C[C@H](S(=O)(=O)c3ccc(F)cc3C(F)(F)F)C[C@H]2C(=O)O)n(C2CCC2)n1 -US20140057902A1,6,COC(=O)CC1c2ccc(F)c(Br)c2CCN1C(=O)CNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCC(=O)N1CCc2c(ccc(F)c2Br)C1CC(=O)O -US20130196974A1,1,CC(C)(C)OC(=O)N1[C@H](C=O)COC1(C)C.NCc1ccccc1>>CC(C)(C)OC(=O)N1[C@@H](CNCc2ccccc2)COC1(C)C -US06433009B1,2,CC(C)c1cc(Cl)cc(C(C)C)c1N=C=O.CC1(c2ccc(F)c(S(N)(=O)=O)c2)OCCO1>>CC(C)c1cc(Cl)cc(C(C)C)c1NC(=O)NS(=O)(=O)c1cc(C2(C)OCCO2)ccc1F -US05300506,1,CN(C)S(=O)(=O)Cc1ccc2[nH]cc(CCCOS(C)(=O)=O)c2c1.COc1cncnc1N1CCNCC1>>COc1cncnc1N1CCN(CCCc2c[nH]c3ccc(CS(=O)(=O)N(C)C)cc23)CC1 -US20060281771A1,2,CC(C)c1ccc(CC(=O)O)cc1.COc1cc2ncnc(N3CCC(N)CC3)c2cc1OC>>COc1cc2ncnc(N3CCC(NC(=O)Cc4ccc(C(C)C)cc4)CC3)c2cc1OC -US20130172328A1,1,CCOC(CBr)OCC.Clc1nc2ccccc2[nH]1>>CCOC(Cn1c(Cl)nc2ccccc21)OCC -US20150175584A1,1,CCI.COc1ccc2c(N[C@@H]3CCOC3)ncnc2c1OC>>CCN(c1ncnc2c(OC)c(OC)ccc12)[C@@H]1CCOC1 -US06683090B1,2,N[C@H]1CN2CCC1CC2.O=C(O)/C=C/c1ccc([N+](=O)[O-])o1>>O=C(/C=C/c1ccc([N+](=O)[O-])o1)N[C@H]1CN2CCC1CC2 -US20040002497A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(-c2cc(COS(C)(=O)=O)c(=O)n(Cc3c(Cl)cccc3Cl)n2)ccc1F>>Cc1cc(-c2cc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(=O)n(Cc3c(Cl)cccc3Cl)n2)ccc1F -US20150119390A1,1,C1=COCCC1.CC(O)c1ccc(Br)nc1>>CC(OC1CCCCO1)c1ccc(Br)nc1 -US20110046134A1,2,NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1.O=C(O)c1ccc2c(c1)Cc1ccccc1-2>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1ccc2c(c1)Cc1ccccc1-2 -US20110230497A1,3,CCCS(=O)(=O)N1CCC(CC(=O)Nc2ccc(Br)nc2)CC1.OB(O)c1cc(F)cc(F)c1>>CCCS(=O)(=O)N1CCC(CC(=O)Nc2ccc(-c3cc(F)cc(F)c3)nc2)CC1 -US20080132542A1,1,CCOC(=O)CBr.Fc1ccc(Br)c(OC2CCN(c3noc(-c4cc[nH]n4)n3)CC2)c1>>CCOC(=O)Cn1ccc(-c2nc(N3CCC(Oc4cc(F)ccc4Br)CC3)no2)n1 -US20090291945A1,6,CC[C@@H](CNc1ccc(OC(C)C(=O)OC)cc1OC)NC(=O)[C@H](CC(C)(C)F)N[C@@H](c1ccccc1)C(F)(F)F>>CC[C@@H](CNc1ccc(OC(C)C(=O)O)cc1OC)NC(=O)[C@H](CC(C)(C)F)N[C@@H](c1ccccc1)C(F)(F)F -US20060241172A1,3,Cc1ccc(S(=O)(=O)OC[C@H]2COc3cc(Cl)cc(OS(=O)(=O)C(F)(F)F)c3O2)cc1.OB(O)c1cc(Cl)ccc1Cl>>Cc1ccc(S(=O)(=O)OC[C@H]2COc3cc(Cl)cc(-c4cc(Cl)ccc4Cl)c3O2)cc1 -US20070287695A1,1,CCOC(=O)N1CCC(=O)C1.O=C1N[C@@H]2CCCC[C@H]2N1C1CCNCC1>>CCOC(=O)N1CCC(N2CCC(N3C(=O)N[C@@H]4CCCC[C@H]43)CC2)C1 -US20110034507A1,6,COC(=O)c1cccc(N2Cc3ccc(OC)cc3CC2=O)c1>>COC(=O)c1cccc(N2Cc3ccc(O)cc3CC2=O)c1 -US06297233B1,7,Cc1cc2cc([N+](=O)[O-])ccc2o1>>Cc1cc2cc(N)ccc2o1 -US20120295897A1,9,COc1cc(O)c(C2(O)C(=O)N(C(c3ccccc3)c3ccccc3)c3ccccc32)cc1F>>COc1cc(O)c(C2C(=O)N(C(c3ccccc3)c3ccccc3)c3ccccc32)cc1F -US20110224208A1,2,CNC.COCCN1C(=O)c2ccccc2C(C(=O)Nc2ccc(C(=O)O)cc2)C1c1cccs1>>COCCN1C(=O)c2ccccc2C(C(=O)Nc2ccc(C(=O)N(C)C)cc2)C1c1cccs1 -US20080153850A1,3,COC(=O)c1ccc(C)nc1Cl.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(B(O)O)ccc1Cl>>COC(=O)c1ccc(C)nc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 -US05665718,9,CN1Cc2c(C(N)=O)ncn2-c2ccc(Cl)cc2C1=O>>CN1Cc2c(C#N)ncn2-c2ccc(Cl)cc2C1=O -US04923857,3,C=CCOC(=O)C(N1C(=O)[C@@H]([C@@H](CO[SiH](C)C)C(C)(C)C)[C@H]1[C@@H](C)C(C)=O)=P(c1ccccc1)(c1ccccc1)c1ccccc1.C=CCOC(=O)N1CCC[C@H]1C=O>>C=CCOC(=O)C(N1C(=O)[C@@H]([C@@H](CO[SiH](C)C)C(C)(C)C)[C@H]1[C@@H](C)C(=O)CC(O)[C@@H]1CCCN1C(=O)OCC=C)=P(c1ccccc1)(c1ccccc1)c1ccccc1 -US20140200227A1,2,CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(N)cnc3ccccc23)C1.O=C(O)c1csc(-c2c(F)cccc2F)n1>>CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(NC(=O)c3csc(-c4c(F)cccc4F)n3)cnc3ccccc23)C1 -US05153214,1,CCOC(=O)CCCC(O)CCC#N.Oc1cccnc1>>CCOC(=O)CCCC(CCC#N)Oc1cccnc1 -US20130281433A1,1,CN(C)C(=O)N1CCNCC1.COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(Cl)n3)sc2c1-c1ccc(Cl)cc1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(N4CCN(C(=O)N(C)C)CC4)n3)sc2c1-c1ccc(Cl)cc1 -US20090170847A1,6,COC(=O)c1ccnc2[nH]c(-c3ccccc3)nc12>>O=C(O)c1ccnc2[nH]c(-c3ccccc3)nc12 -US04145347,2,CC(C)N(CCN)C(C)C.CCOC(=O)CN1C(=O)CCC1C>>CC1CCC(=O)N1CC(=O)NCCN(C(C)C)C(C)C -US20090111776A1,1,CC(C)=O.O=C(O)[C@@H]1CCCN1>>CC(C)N1CCC[C@H]1C(=O)O -US06642226B2,2,O=C(Cl)Cc1ccccc1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCNCC2)[C@H](c2ccccc2)C1>>O=C(Cc1ccccc1)N1CCN([C@H]2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C[C@H]2c2ccccc2)CC1 -US20130274266A1,2,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)Cn2c1nc(Cl)c2C#N.O=C(O)c1ccc(Cl)cn1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)Cn2c1nc(Cl)c2C#N -US20130324516A1,3,Brc1ccnc(NCCN2CCCC2)c1.CC1(C)OB(c2ccc3ncnc(N)c3c2)OC1(C)C>>Nc1ncnc2ccc(-c3ccnc(NCCN4CCCC4)c3)cc12 -US08349836B2,2,CC(C)(C)OC(=O)NCc1cccc(C(=O)O)c1.NCCN1CCCC1>>CC(C)(C)OC(=O)NCc1cccc(C(=O)NCCN2CCCC2)c1 -US20060024330A1,2,CC(=O)OC(C)=O.O=C1CNCCN1>>CC(=O)N1CCNC(=O)C1 -US05252572,2,Cc1ccc2ncc(C(=O)O)c(=O)n2c1.NC1CCCC1>>Cc1ccc2ncc(C(=O)NC3CCCC3)c(=O)n2c1 -US05604226,8,COc1ccc(CNc2c(OCCSc3ccccc3Cl)n[nH]c(=O)c2Br)cc1OC.O=C(OO)c1cccc(Cl)c1>>COc1ccc(CNc2c(OCCS(=O)c3ccccc3Cl)n[nH]c(=O)c2Br)cc1OC -US20130040930A1,1,CCOC(=O)c1ccc(Cl)nc1.c1ccc2[nH]cnc2c1>>CCOC(=O)c1ccc(-n2cnc3ccccc32)nc1 -US06444672B1,6,COC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1)c1ccccc1>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)c1ccccc1 -US06258961B1,3,C=O.COC(=O)C(NCCc1cccs1)c1ccccc1Cl>>COC(=O)C(c1ccccc1Cl)N1CCc2sccc2C1 -US20150038488A1,3,CC1(C)C(=O)Nc2cc(B3OC(C)(C)C(C)(C)O3)ccc21.C[C@@H](Oc1cc(Cl)cn2ncc(C3CC3)c12)[C@H]1CNC(=O)C1>>C[C@@H](Oc1cc(-c2ccc3c(c2)NC(=O)C3(C)C)cn2ncc(C3CC3)c12)[C@H]1CNC(=O)C1 -US06162824,3,Cc1cccc([Mg+])c1.O=C1c2ccccc2-c2ccccc21>>Cc1cccc(C2(O)c3ccccc3-c3ccccc32)c1 -US20090029975A1,2,CCN(CC)CCO.CS(=O)(=O)c1cc(CCC(=O)O)nc(-c2nc(=O)c3ccc(Cl)cc3s2)c1>>CCN(CC)CCOC(=O)CCc1cc(S(C)(=O)=O)cc(-c2nc(=O)c3ccc(Cl)cc3s2)n1 -US20100216788A1,1,Cc1nccn1-c1cccc(O)c1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>Cc1nccn1-c1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1 -US20050004112A1,2,CC1CCN(c2ccc(CO)cc2N)CC1.N#Cc1ccc(C(=O)Cl)o1>>CC1CCN(c2ccc(CO)cc2NC(=O)c2ccc(C#N)o2)CC1 -US07745438B2,3,CC(=O)N[C@@H](Cc1cc(F)cc(Br)c1)[C@H](O)[C@H]1CO[C@@H](OCC(C)(C)C)[C@H](C)N1C(=O)OC(C)(C)C.CC(C)CC[Zn+]>>CC(=O)N[C@@H](Cc1cc(F)cc(CCC(C)C)c1)[C@H](O)[C@H]1CO[C@@H](OCC(C)(C)C)[C@H](C)N1C(=O)OC(C)(C)C -US08188101B2,1,C=O.Cc1nccn1-c1ccc(Nc2nc3c(c(NC[C@@H]4CCCO4)n2)CNCC3)cc1>>Cc1nccn1-c1ccc(Nc2nc3c(c(NC[C@@H]4CCCO4)n2)CN(C)CC3)cc1 -US08399507B2,7,COC(=O)c1c(F)ccc(I)c1C>>Cc1c(I)ccc(F)c1CO -US20140073650A1,2,CC(C)NCc1nc(-c2ccc(C(F)(F)F)cc2)no1.O=C(Cl)COc1ccc(C(F)(F)F)cc1>>CC(C)N(Cc1nc(-c2ccc(C(F)(F)F)cc2)no1)C(=O)COc1ccc(C(F)(F)F)cc1 -US07183277B2,7,N#CN=C1NCCN1c1ccc([N+](=O)[O-])cc1>>N#CN=C1NCCN1c1ccc(N)cc1 -US04634715,9,CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)Cl.NN>>CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)NN -US20050014787A1,2,CS(=O)(=O)Cl.O=C1OCCN1c1ccc(CCO)cc1>>CS(=O)(=O)OCCc1ccc(N2CCOC2=O)cc1 -US05599770,1,C=CCO.Clc1cc(Cl)nc(OCc2ccccc2)n1>>C=CCOc1cc(Cl)nc(OCc2ccccc2)n1 -US08618094B2,6,CC(C)(C)OC(=O)N[C@@]12CC[C@H](F)[C@@H]1CN(C(=O)OCc1ccccc1)C2>>CC(C)(C)OC(=O)N[C@@]12CC[C@H](F)[C@@H]1CNC2 -US20090326058A1,1,CC(=O)c1ccccc1F.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(Oc2ccccc2C(C)=O)cc1 -US06218385B1,1,BrCCOc1ccccc1.C=CCn1c(N)nc(N2CCc3ccccc3CC2)c(C#N)c1=O>>C=CCn1c(NCCOc2ccccc2)nc(N2CCc3ccccc3CC2)c(C#N)c1=O -US20090275569A1,1,CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1.COc1ccc(Cl)c(-c2cc(C)c3nc(N)nnc3c2)c1>>COc1ccc(Cl)c(-c2cc(C)c3nc(Nc4ccc(S(=O)(=O)N5CCN(C)CC5)cc4)nnc3c2)c1 -US05466704,1,CCOC(=O)c1cc2ccccc2[nH]1.Cc1ccc(Br)cc1>>CCOC(=O)c1cc2ccccc2n1-c1ccc(C)cc1 -US20060241302A1,2,Nc1cccc(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(Cl)cc2)n1.O=C(O)Cc1ccccn1>>O=C(Cc1ccccn1)Nc1cccc(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(Cl)cc2)n1 -US20110178053A1,1,C=O.c1cncc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(N5CCNCC5)cc4)cc23)c1>>CN1CCN(c2ccc(-c3cnc4[nH]c5cnc(-c6cccnc6)cc5c4c3)cc2)CC1 -US05929097,1,CCNCC.COC(=O)c1cc(CBr)cc(C)c1N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1>>CCN(CC)Cc1cc(C)c(N(Cc2ccccc2)S(=O)(=O)c2ccc(OC)cc2)c(C(=O)OC)c1 -US20040132960A1,2,O=C(O)c1cc(O)cc(O)c1.OCC(Cl)(Cl)Cl>>O=C(OCC(Cl)(Cl)Cl)c1cc(O)cc(O)c1 -US07041687B2,3,Cc1cc([N+](=O)[O-])cc(Br)c1N.OB(O)c1ccccc1>>Cc1cc([N+](=O)[O-])cc(-c2ccccc2)c1N -US20130085127A1,6,COC(=O)c1cccc(C(F)(F)N2CCC(OC(c3ccccc3)c3ccccc3)CC2)n1>>O=C(O)c1cccc(C(F)(F)N2CCC(OC(c3ccccc3)c3ccccc3)CC2)n1 -US20110112158A1,10,Cc1ccc2on(C(c3ccccc3)(c3ccccc3)c3ccccc3)c(=O)c2c1.O=C1CCC(=O)N1Br>>O=c1c2cc(CBr)ccc2on1C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20100120160A1,6,CC(=O)Nc1ccc(C=O)cc1[N+](=O)[O-]>>Nc1ccc(C=O)cc1[N+](=O)[O-] -US05288743,1,CCOC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(O)ccc2n1Cc1ccc(Cl)cc1.ClCc1cccnc1>>CCOC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OCc3cccnc3)ccc2n1Cc1ccc(Cl)cc1 -US06642381B2,1,N#Cc1cccc(CBr)c1.Nc1nc(N)c2nc(CN3CCNCC3)nnc2n1>>N#Cc1cccc(CN2CCN(Cc3nnc4nc(N)nc(N)c4n3)CC2)c1 -US06093731,1,CC(C)CC(NC(=O)c1ccc2c(Cl)cnc(Cl)c2c1)C(=O)OC(C)(C)C.N=C(N)N>>CC(C)CC(NC(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1)C(=O)OC(C)(C)C -US05057515,9,CCCN1CCC[C@H]2Cc3nc(Br)ccc3C[C@@H]21>>CCCN1CCC[C@H]2Cc3ncccc3C[C@@H]21 -US07091222B2,3,CC(C)n1cc(I)nc1C1CC1.Cc1cc(C#C[Si](C)(C)C)ccn1>>Cc1cc(C#Cc2cn(C(C)C)c(C3CC3)n2)ccn1 -US06469039B1,6,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)C1CCCC1>>Cn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)C3CCCC3)ccc21 -US20150126490A1,3,CC1(C)OB(c2ccc(F)nc2)OC1(C)C.Cn1ccc(Br)cc1=O>>Cn1ccc(-c2ccc(F)nc2)cc1=O -US04608375,1,Cn1c(=O)c2ccccc2n(CCCBr)c1=O.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Cn1c(=O)c2ccccc2n(CCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)c1=O -US06124354,2,CCN(CC)CCCO.O=C(Cl)C1(c2ccccc2)CCC1>>CCN(CC)CCCOC(=O)C1(c2ccccc2)CCC1 -US08828987B2,2,COC(=O)c1ccc(C2(N)CC2)cc1.O=C(O)c1cc(Cl)cnc1N1CCC(Oc2cccc(F)c2)C1>>COC(=O)c1ccc(C2(NC(=O)c3cc(Cl)cnc3N3CCC(Oc4cccc(F)c4)C3)CC2)cc1 -US20100317680A1,1,Cn1cc(N)cn1.OC1(c2ccccc2Nc2nc(Cl)ncc2Cl)CCOCC1>>Cn1cc(Nc2ncc(Cl)c(Nc3ccccc3C3(O)CCOCC3)n2)cn1 -US20130225556A1,2,C=C1CC(C#N)(CO)C1.CS(=O)(=O)Cl>>C=C1CC(C#N)(COS(C)(=O)=O)C1 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3sc(C)c(Cl)c23)cc1Cl.Cc1ncc[nH]1>>COc1ccc(CNc2nc(-n3ccnc3C)nc3sc(C)c(Cl)c23)cc1Cl -US20130261128A1,3,CCOC(=O)C1(COc2cc(C)c(B3OC(C)(C)C(C)(C)O3)cn2)CCC1.C[Si](C)(C)CCOCn1cc(C(F)(F)F)nc1-c1ccc(Br)cn1>>CCOC(=O)C1(COc2cc(C)c(-c3ccc(-c4nc(C(F)(F)F)cn4COCC[Si](C)(C)C)nc3)cn2)CCC1 -US20150126449A1,6,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(-c5ccccc5)c(F)ccc4nn23)CC1>>O=c1cc(C2CCNCC2)n2nc3ccc(F)c(-c4ccccc4)c3c2[nH]1 -US04727081,1,NCCCOc1cccc(CN2CCOCC2)c1.Nc1nnc(Br)s1>>Nc1nnc(NCCCOc2cccc(CN3CCOCC3)c2)s1 -US08236950B2,1,CC(=O)Nc1ccc(Sc2ccc(O)cc2N)cc1.Cc1cccc(CBr)c1>>CC(=O)Nc1ccc(Sc2ccc(OCc3cccc(C)c3)cc2N)cc1 -US06458781B1,2,CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)O.NCCC(c1ccccc1)c1ccccc1>>CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)NCCC(c1ccccc1)c1ccccc1 -US05607960,3,C=CC(C)(C)O.O=C1c2ccccc2C(=O)N1CCc1c[nH]c2ccc(Br)cc12>>CC(C)(O)C=Cc1ccc2[nH]cc(CCN3C(=O)c4ccccc4C3=O)c2c1 -US07772244B2,6,CN1CCC2(CC1)CCN(Cc1ccccc1)CC2>>CN1CCC2(CCNCC2)CC1 -US20120232056A1,6,COC(=O)c1ccc2nc(-c3ccc4c(c3)OCCCO4)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc2c(c1)OCCCO2 -US08049015B2,1,CCN.O=Cc1cc(C(F)(F)F)ccc1Br>>CCNCc1cc(C(F)(F)F)ccc1Br -US08188098B2,6,CS(=O)(=O)c1ccc(Oc2ncnc3c2cnn3C2CCCCO2)cc1>>CS(=O)(=O)c1ccc(Oc2ncnc3[nH]ncc23)cc1 -US07358370B2,1,CC1(C)CC(=O)c2c(C(F)F)nn(-c3ccc(C(N)=O)c(Br)c3)c2C1.NC1CCSCC1>>CC1(C)CC(=O)c2c(C(F)F)nn(-c3ccc(C(N)=O)c(NC4CCSCC4)c3)c2C1 -US08183262B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.CCOc1cc(-c2cc(C(F)(F)F)nc(-c3cccc(Br)c3)n2)ccc1C(F)(F)F>>CCOc1cc(-c2cc(C(F)(F)F)nc(-c3cccc(-c4ccc(N)nc4)c3)n2)ccc1C(F)(F)F -US20100093748A1,1,CCOC(=O)C1(NC(=O)OC(C)(C)C)CCNCC1.Clc1ncnc2[nH]ccc12>>CCOC(=O)C1(NC(=O)OC(C)(C)C)CCN(c2ncnc3[nH]ccc23)CC1 -US06605620B1,6,CCOC(=O)c1ccnc(-c2cc(OC)c(Cl)c(OC)c2)c1>>COc1cc(-c2cc(C(=O)O)ccn2)cc(OC)c1Cl -US20120130080A1,9,CNC(=O)c1cc(Br)cc(C)c1N.[C-]#N>>CNC(=O)c1cc(C#N)cc(C)c1N -US20080091031A1,3,CB1OB(C)OB(C)O1.Nc1ccc(S(F)(F)(F)(F)F)cc1Br>>Cc1cc(S(F)(F)(F)(F)F)ccc1N -US04111937,2,C1COCCN1.CC(=O)N(C)c1c(I)c(N)c(I)c(C(=O)O)c1I>>CC(=O)N(C)c1c(I)c(N)c(I)c(C(=O)N2CCOCC2)c1I -US20100249095A1,2,CC(C)(C)OC(=O)N1CCC2(CCCNC2)CC1.O=C(O)c1ccc2c(c1)[C@H](NC(=O)c1ccccc1Cl)CC2>>CC(C)(C)OC(=O)N1CCC2(CCCN(C(=O)c3ccc4c(c3)[C@H](NC(=O)c3ccccc3Cl)CC4)C2)CC1 -US05939439,7,O=C(CCCCBr)OCc1ccc(N2CCCCC2=O)cc1>>O=C1CCCCN1c1ccc(CO)cc1 -US20120142633A1,2,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](N)CC1.COc1ccc(-c2ccnc3c(C(=O)O)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)c1>>COc1ccc(-c2ccnc3c(C(=O)N[C@@H]4CC[C@H](NC(=O)OC(C)(C)C)CC4)c(C)n(COCC[Si](C)(C)C)c23)c(OCC2CC2)c1 -US05232917,7,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@@H](O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C -US09107411B2,6,CCOC(=O)c1cc2cc(C(=O)NC(c3cccc(C(F)(F)F)c3)C(F)(F)F)n(CC)c2cc1Cl>>CCn1c(C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)cc2cc(C(=O)O)c(Cl)cc21 -US20130143929A1,2,CNOC.Cc1nc(Cl)n(-c2c(F)cc(F)cc2Cl)c1C(=O)O>>CON(C)C(=O)c1c(C)nc(Cl)n1-c1c(F)cc(F)cc1Cl -US20020193367A1,1,C1CNC1.CC(C)(C)OC(=O)Nc1cc(Cl)c(C(F)(F)F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(N2CCC2)c(C(F)(F)F)cc1[N+](=O)[O-] -US04945098,2,C=C(CO)COC(=O)OCCCCCCCCCCCCCCCCCC.O=C(O)CCCCCCBr>>C=C(COC(=O)CCCCCCBr)COC(=O)OCCCCCCCCCCCCCCCCCC -US20140288123A1,6,COC(=O)c1ccc(C(C)Oc2ccncn2)cc1>>CC(Oc1ccncn1)c1ccc(C(=O)O)cc1 -US20120077812A1,6,CC(C)(C)OC(=O)N1CCC(COc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)CC1>>CS(=O)(=O)c1ccc(-c2ccc(OCC3CCNCC3)cn2)cc1 -US20090203697A1,6,COc1cc(/C=C(\CCCCl)C(=O)OC(C)(C)C)ccc1-n1cnc(C)n1>>COc1cc(/C=C(\CCCCl)C(=O)O)ccc1-n1cnc(C)n1 -US20140378462A1,1,C#CCBr.COC(=O)c1c(O)cccc1NC(=O)C(C)(C)C>>C#CCOc1cccc(NC(=O)C(C)(C)C)c1C(=O)OC -US20120252780A1,3,Brc1ccc2c(n1)NCCO2.OB(O)c1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(-c2ccc3c(n2)NCCO3)c1 -US20100144760A1,1,COC(=O)c1nc(C)ccc1I.c1nc[nH]n1>>COC(=O)c1nc(C)ccc1-n1cncn1 -US20090149501A1,3,CC1(C)C(C(=O)Cl)C1(C)C.COC(=O)c1cccc2cc[nH]c12>>COC(=O)c1cccc2c(C(=O)C3C(C)(C)C3(C)C)c[nH]c12 -US20100105900A1,1,CI.Cc1cccc(C#Cc2ccc(S(=O)(=O)N[C@H](CC(=O)OCc3ccccc3)CN(C)C)s2)c1>>Cc1cccc(C#Cc2ccc(S(=O)(=O)N[C@H](CC(=O)OCc3ccccc3)C[N+](C)(C)C)s2)c1 -US20090253677A1,2,Cc1cc(C(=O)Cl)no1.O=C(NC12CCC(CC1)Cn1c2nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)C(=O)N1CCNCC1>>Cc1cc(C(=O)N2CCN(C(=O)C(=O)NC34CCC(CC3)Cn3c4nc(C(=O)NCc4ccc(F)cc4)c(O)c3=O)CC2)no1 -US20150018343A1,6,Cc1cnc2c3c(nn2c1C)CN(C(=O)OC(C)(C)C)C3>>Cc1cnc2c3c(nn2c1C)CNC3 -US20030144326A1,1,CCOC(=O)C(=Cc1ccc(N2CCC(=O)CC2)cc1)C(=O)OCC.CS(=O)(=O)Nc1cc(C(O)CN)ccc1O>>CCOC(=O)C(=Cc1ccc(N2CCC(NCC(O)c3ccc(O)c(NS(C)(=O)=O)c3)CC2)cc1)C(=O)OCC -US20140200344A1,7,N[C@@H]1CC[C@@H](C(=O)O)CC1>>N[C@@H]1CC[C@@H](CO)CC1 -US05789423,1,CC(C)(C)OC(=O)N1CCC[C@H](N)[C@@H]1c1ccccc1.COc1ccc(C(C)(C)C2SCCS2)cc1C=O>>COc1ccc(C(C)(C)C2SCCS2)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1 -US20060223850A1,3,Brc1ccccc1Br.CC(=O)c1ccc(B(O)O)cc1>>CC(=O)c1ccc(-c2ccccc2Br)cc1 -US20040110945A1,1,CI.O=Cc1c[nH]c2ccc(F)cc12>>Cn1cc(C=O)c2cc(F)ccc21 -US20090264650A1,2,NS(=O)(=O)c1ccc(C(F)(F)F)cc1.O=C(O)COc1ccc(CC2CCN(C3C4CC5CC3CC(O)(C5)C4)C2=O)c(Cl)c1>>O=C(COc1ccc(CC2CCN(C3C4CC5CC3CC(O)(C5)C4)C2=O)c(Cl)c1)NS(=O)(=O)c1ccc(C(F)(F)F)cc1 -US20130225620A1,7,Cc1c[nH]c2ccc(C#N)cc12>>Cc1c[nH]c2ccc(CN)cc12 -US20030105100A1,1,NCCC(O)C(F)(F)F.O=Cc1cccc(OC(F)(F)C(F)F)c1>>OC(CCNCc1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F -US20080070933A1,8,CCn1nc(CO)c2c1C(=O)CC(C)(C)C2>>CCn1nc(C=O)c2c1C(=O)CC(C)(C)C2 -US08354413B2,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(Cn3ccc(=O)c4ccccc43)ccc2F)CC1>>O=C(c1cc(Cn2ccc(=O)c3ccccc32)ccc1F)N1CCNCC1 -US20050159462A1,1,C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](CCc1cccc2oc(-c3ccc(Cl)cc3)nc12)OS(C)(=O)=O.NC(=O)c1c[nH]cn1>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CCc1cccc2oc(-c3ccc(Cl)cc3)nc12)n1cnc(C(N)=O)c1 -US08349831B2,7,COc1ccc(C(=O)N[C@H](C)c2cccc(Cl)c2)cc1S(=O)(=O)N1CCOCC1>>COc1ccc(CN[C@H](C)c2cccc(Cl)c2)cc1S(=O)(=O)N1CCOCC1 -US06514996B2,2,CC(C)(C)c1ccc(N)cc1.COc1cccc2cc(C(=O)O)oc12>>COc1cccc2cc(C(=O)Nc3ccc(C(C)(C)C)cc3)oc12 -US20060046999A1,1,CC(C)(C)OC(=O)NCCBr.Nc1c(C(=O)c2ccc(F)cc2)ccc(=O)n1-c1c(F)cc(O)cc1F>>CC(C)(C)OC(=O)NCCOc1cc(F)c(-n2c(N)c(C(=O)c3ccc(F)cc3)ccc2=O)c(F)c1 -US20130150379A1,1,CCOC(=O)C(C)(C)N1CCC(=O)CC1.NCc1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>CCOC(=O)C(C)(C)N1CCC(NCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)CC1 -US08748426B2,2,CCOC(=O)c1nnc(-c2ccccc2)[nH]1.COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O>>COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4nnc(-c5ccccc5)[nH]4)cc3)cc2C1=O -US20070037787A1,1,BrCc1ccc(CBr)cc1.O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(O)cc2)N1c1ccc(F)cc1>>O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(OCc3ccc(CBr)cc3)cc2)N1c1ccc(F)cc1 -US07297820B2,3,CCOP(=O)(Cc1cccc(I)c1)OCC.COc1ccc(C=O)cc1>>COc1ccc(/C=C/c2cccc(I)c2)cc1 -US20140249133A1,6,COc1cnc(-c2nn(Cc3ccc(C#C[Si](C)(C)C)cc3F)c3ccccc23)nc1Nc1ccncc1>>C#Cc1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1 -US04073917,1,CC(C)COc1ccccc1O.CC(C)N(CCCl)C(C)C>>CC(C)COc1ccccc1OCCN(C(C)C)C(C)C -US20140323468A1,2,CC(=O)Cl.c1cncc(-c2cnc3c(c2)CCCN3)c1>>CC(=O)N1CCCc2cc(-c3cccnc3)cnc21 -US05348944,2,CCOC(=O)C1CC2CCCCC2N1.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CCOC(=O)[C@H]1CC2CCCCC2N1C(=O)[C@H](C)NC(=O)OCc1ccccc1 -US20050148627A1,7,CCOC(=O)C1=Cc2cc(C=O)cc(C)c2OC1C(F)(F)F>>CCOC(=O)C1=Cc2cc(CO)cc(C)c2OC1C(F)(F)F -US20140171405A1,3,CC(C)(C)OC(=O)N1CCc2cc(B3OC(C)(C)C(C)(C)O3)ccc2C1.COc1cc(OC)c(F)c(-c2ncc3c(I)n[nH]c3n2)c1F>>COc1cc(OC)c(F)c(-c2ncc3c(-c4ccc5c(c4)CCN(C(=O)OC(C)(C)C)C5)n[nH]c3n2)c1F -US08592463B2,6,CC(C)(C)OC(=O)N1CCN(C(=O)C2CCN(c3ccc(Cl)c(-c4nc5ccccc5[nH]4)c3)CC2)CC1>>O=C(C1CCN(c2ccc(Cl)c(-c3nc4ccccc4[nH]3)c2)CC1)N1CCNCC1 -US07273877B2,3,C#C[Si](C)(C)C.O=C(NCCCO)c1c[nH]c(=O)cc1Nc1ccc(I)cc1F>>C[Si](C)(C)C#Cc1ccc(Nc2cc(=O)[nH]cc2C(=O)NCCCO)c(F)c1 -US20100168418A1,6,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(Cl)c3ccccc32)CC1>>O=c1cc(Cl)c2ccccc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1 -US20040010009A1,1,C=O.CC(C)(C)OC(=O)N1CCC(Oc2ccc(NC/C=C/c3cccc(C#N)c3)cc2)CC1>>CN(C/C=C/c1cccc(C#N)c1)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US05214040,1,CCOCCn1c(CN2CCCNCC2)nc2ccccc21.ClCCCCn1cccc1>>CCOCCn1c(CN2CCCN(CCCCn3cccc3)CC2)nc2ccccc21 -US05714479,6,COC(=O)c1nc(COCOCC[Si](C)(C)C)ccc1C(=O)c1ccc2c(c1)OCO2>>C[Si](C)(C)CCOCOCc1ccc(C(=O)c2ccc3c(c2)OCO3)c(C(=O)O)n1 -US20150246922A1,3,Cc1c2n(c3c(Br)cc(Cl)cc13)CCCNC2=O.OB(O)c1ccc(F)cc1>>Cc1c2n(c3c(-c4ccc(F)cc4)cc(Cl)cc13)CCCNC2=O -US20070032485A1,1,CC[C@@H]1C[C@H](Nc2ncc(O)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OCC(C)(C)C(=O)OC.COCCO>>CC[C@@H]1C[C@H](Nc2ncc(OCCOC)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OCC(C)(C)C(=O)OC -US05049576,2,COc1cc(C(=O)O)ccc1Cc1cn(CCC(N)=O)c2ccc(C(=O)NCC3CCCC3)cc12.Cc1ccccc1S(N)(=O)=O>>COc1cc(C(=O)NS(=O)(=O)c2ccccc2C)ccc1Cc1cn(CCC(N)=O)c2ccc(C(=O)NCC3CCCC3)cc12 -US20150141406A1,3,COc1nccc2c1c(OS(=O)(=O)C(F)(F)F)nn2C1CCCC1.NC(=O)c1cccc(B(O)O)c1>>COc1nccc2c1c(-c1cccc(C(N)=O)c1)nn2C1CCCC1 -US20050250792A1,1,CN.O=C1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 -US20060122064A1,6,CC#CCOc1ccc(CCC(=O)OCC)cc1OC>>CC#CCOc1ccc(CCC(=O)O)cc1OC -US05189043,1,CCCN.CCOC(=O)/C=C/CBr>>CCCNC/C=C/C(=O)OCC -US20080032964A1,7,O=C(CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(OCc2ccccc2)cc1)c1ccc(F)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(OCc3ccccc3)cc2)N1c1ccc(F)cc1 -US04118487,1,OC(c1ccccc1)c1ccc(-c2ccccc2)cc1.c1c[nH]cn1>>c1ccc(-c2ccc(C(c3ccccc3)n3ccnc3)cc2)cc1 -US08716484B1,1,Ic1ccc(-c2ccccc2)cc1.Nc1ccc(-c2ccccc2)cc1-c1ccccc1>>c1ccc(-c2ccc(Nc3ccc(-c4ccccc4)cc3-c3ccccc3)cc2)cc1 -US06890932B2,1,CC(C)(C)OC(=O)CBr.COC(=O)c1ccccc1NC(=O)Cc1ccc(Oc2ccc(O)cc2)cc1>>COC(=O)c1ccccc1NC(=O)Cc1ccc(Oc2ccc(OCC(=O)OC(C)(C)C)cc2)cc1 -US07674789B2,3,CSc1nc(Cl)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2.Cc1ccc(NC(=O)c2ccsc2)cc1B1OC(C)(C)C(C)(C)O1>>CSc1nc(-c2cc(NC(=O)c3ccsc3)ccc2C)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2 -US20090298823A1,1,Clc1nc(NCCCN2CCOCC2)c2cc[nH]c2n1.Nc1ccc2cn[nH]c2c1>>c1cc2c(NCCCN3CCOCC3)nc(Nc3ccc4cn[nH]c4c3)nc2[nH]1 -US20090118261A1,1,Cc1ccc(NC(=O)c2cc(O)cc(C(C)(C)C#N)c2)cc1Nc1ccc2ncn(C)c(=O)c2c1.ClCCN1CCCC1>>Cc1ccc(NC(=O)c2cc(OCCN3CCCC3)cc(C(C)(C)C#N)c2)cc1Nc1ccc2ncn(C)c(=O)c2c1 -US04016148,6,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)P(=O)(O)O>>CC(C)C[C@H](N)C(=O)N[C@@H](C)P(=O)(O)O -US20110034507A1,1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.COC(=O)c1ccc(-c2ccc3cc(O)ccc3c2)cn1>>COC(=O)c1ccc(-c2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3c2)cn1 -US04562186,8,O=C(OO)c1cccc(Cl)c1.O=C(c1ccccc1)c1noc(CSc2ccccc2)n1>>O=C(c1ccccc1)c1noc(CS(=O)c2ccccc2)n1 -US20060063804A1,1,CC(=O)Nc1cc(O)c2cc(Br)ccc2n1.CCI>>CCOc1cc(NC(C)=O)nc2ccc(Br)cc12 -US07425551B2,2,NCCC(F)(F)C(F)(F)F.O=C(O)CC(=O)N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21>>O=C(CC(=O)N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21)NCCC(F)(F)C(F)(F)F -US20090042852A1,2,CCc1cnc(-c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2NC)o1.NS(=O)(=O)c1ccc(Cl)s1>>CCc1cnc(-c2cnc(N3CCC(C(=O)NS(=O)(=O)c4ccc(Cl)s4)CC3)c(Cl)c2NC)o1 -US20090149439A1,2,CN.Cc1cc(C(=O)O)ncc1C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(F)cc1>>CNC(=O)c1cc(C)c(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(F)cc2)cn1 -US20150141427A1,2,Nc1ccc(SC(F)(F)F)cc1.O=C(O)c1cccc(-c2cncnc2)c1>>O=C(Nc1ccc(SC(F)(F)F)cc1)c1cccc(-c2cncnc2)c1 -US20100298377A1,3,CON(C)C(=O)[C@@H]1CCCCN1C(=O)OC(C)(C)C.FC(F)(F)c1cccc(Br)c1>>CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)c1cccc(C(F)(F)F)c1 -US08008350B2,3,COc1ccc(C)cc1B(O)O.O=S(=O)(c1ccccc1)c1ccc(Br)cc1F>>COc1ccc(C)cc1-c1ccc(S(=O)(=O)c2ccccc2)c(F)c1 -US20110082129A1,2,Cn1c(-c2cncc(CN)c2)cc2ccc(Cl)cc21.O=S(=O)(Cl)C(F)(F)F>>Cn1c(-c2cncc(CNS(=O)(=O)C(F)(F)F)c2)cc2ccc(Cl)cc21 -US08492397B2,2,C[C@H](O)C(F)(F)F.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>C[C@H](OC(=O)Oc1ccc([N+](=O)[O-])cc1)C(F)(F)F -US06727245B2,2,CCN.O=C(O)c1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1>>CCNC(=O)c1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1 -US06069157,3,C#C[Si](C)(C)C.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1I>>C[Si](C)(C)C#Cc1c(C#N)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N -US06660738B2,3,Brc1ccccn1.Fc1cc(F)c(COC[C@@H]2C[C@@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)CN2c2ncc(Br)cn2)cc1F>>Fc1cc(F)c(COC[C@@H]2C[C@@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)CN2c2ncc(-c3ccccn3)cn2)cc1F -US20070027185A1,1,CC(C)(CO)CNC(=O)OC(C)(C)C.COC(=O)c1ccc(OCCF)cc1O>>COC(=O)c1ccc(OCCF)cc1OCC(C)(C)CNC(=O)OC(C)(C)C -US05869661,1,C1COCCN1.COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>COc1c(N2CCOCC2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.COC(=O)c1nn(-c2cccc(Br)c2)c2cc(C#N)ccc12>>COC(=O)c1nn(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)c2cc(C#N)ccc12 -US07902252B2,6,COC(=O)c1cc2c([nH]1)C(CCc1cccc3ccccc13)CC2>>O=C(O)c1cc2c([nH]1)C(CCc1cccc3ccccc13)CC2 -US07935699B2,7,O=S1(=O)C=Cc2ccccc21>>O=S1(=O)CCc2ccccc21 -US04096254,2,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43CO)[C@@H]1CCC2=O.O=C(O)C12CC3CC(CC(C3)C1)C2>>C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43COC(=O)C34CC5CC(CC(C5)C3)C4)[C@@H]1CCC2=O -US20080194617A1,6,Cc1nn(C)c(-n2ccc3cc(Cl)ccc32)c1/C=C/C(=O)NS(=O)(=O)N1CCC2(CC1)OCCO2>>Cc1nn(C)c(-n2ccc3cc(Cl)ccc32)c1/C=C/C(=O)NS(=O)(=O)N1CCC(=O)CC1 -US20060142347A1,6,COC(=O)c1sc(-c2ccccc2)cc1N(Cc1ccc(-c2cccc(C(F)(F)F)c2)o1)C(=O)c1ccc(Cl)cc1Cl>>O=C(O)c1sc(-c2ccccc2)cc1N(Cc1ccc(-c2cccc(C(F)(F)F)c2)o1)C(=O)c1ccc(Cl)cc1Cl -US07268128B2,2,CNc1ccc(-c2nc3c(c(C4CCCCC4)nn3C)c(=O)[nH]2)c(OC)c1.CS(=O)(=O)Cl>>COc1cc(N(C)S(C)(=O)=O)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1 -US05576188,6,CCOC(=O)CCCCOc1cc(C)c(NC(C)COC)c(CC)c1>>CCc1cc(OCCCCC(=O)O)cc(C)c1NC(C)COC -US05322858,1,BrCCCBr.Sc1ccc(Cl)cc1>>Clc1ccc(SCCCBr)cc1 -US08497376B2,7,CC(C)(C)[SiH2]OC(C)(C)C12C=CC(C(C)(C)O[SiH2]C(C)(C)C)(CC(c3ccc(N)cc3)=C1)O2>>CC(C)(C)[SiH2]OC(C)(C)C12C=C(c3ccc(N)cc3)CC(C(C)(C)O[SiH2]C(C)(C)C)(CC1)O2 -US04404018,2,CC(Oc1cc(Oc2ccc(Br)cc2C#N)ccc1Br)C(=O)Cl.CCCCNCc1ccco1>>CCCCN(Cc1ccco1)C(=O)C(C)Oc1cc(Oc2ccc(Br)cc2C#N)ccc1Br -US20040162303A1,1,CN1CCNCC1.COc1ccc(F)cc1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N>>COc1ccc(F)cc1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCN3CCN(C)CC3)CC2)nc1N -US07598419B2,3,N#CCC(=O)NCc1cccc(F)c1.O=CC=Cc1ccc(O)c(O)c1>>N#C/C(=C\C=C\c1ccc(O)c(O)c1)C(=O)NCc1cccc(F)c1 -US07067534B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.Cc1onc(-c2ccccc2)c1C(=O)Cl>>Cc1onc(-c2ccccc2)c1C(=O)NCCCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1 -US04339612,8,CC(C)(C)C(O)COc1ccc(Cl)cc1>>CC(C)(C)C(=O)COc1ccc(Cl)cc1 -US20140371201A1,3,COc1cc(Br)c(F)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21.OB(O)c1cccc(F)c1>>COc1cc(-c2cccc(F)c2)c(F)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21 -US07176210B2,1,CCNC1(C(N)=O)CCNCC1.Cc1cnc2c(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nn2c1Cl>>CCNC1(C(N)=O)CCN(c2c(C)cnc3c(-c4ccc(Cl)cc4)c(-c4ccccc4Cl)nn23)CC1 -US20120184735A1,2,COc1c(NC(=O)OCC(Cl)(Cl)Cl)cc(C(C)(C)C)cc1C(O)C(F)(F)F.NC1Cc2ccccc2C1>>COc1c(NC(=O)NC2Cc3ccccc3C2)cc(C(C)(C)C)cc1C(O)C(F)(F)F -US05807866,4,O=C(OO)c1cccc(Cl)c1.OC/C=C/c1cccc(Br)c1>>OC[C@@H]1O[C@H]1c1cccc(Br)c1 -US20140142084A1,2,COc1cc(OC)c(Cl)c(COc2cnc(Nc3cnn(C4CCNCC4)c3)nc2)c1Cl.O=C(Cl)C1CC1>>COc1cc(OC)c(Cl)c(COc2cnc(Nc3cnn(C4CCN(C(=O)C5CC5)CC4)c3)nc2)c1Cl -US20070213348A1,6,COC(=O)c1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(O)cc2)cc1>>CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(C(=O)O)cc2)CC(C)(C)C1 -US06875765B2,7,CC(=O)Cc1c(C)ccc2ccccc12>>Cc1ccc2ccccc2c1CC(C)O -US05366970,2,CS(=O)(=O)Cl.O=CNc1ccnn1CCO>>CS(=O)(=O)OCCn1nccc1NC=O -US20070054916A1,3,CN(C)CCNc1ncc2cc(Br)ccc2n1.O=C(NC1CC1)c1ccc(C(F)(F)F)c(Cl)c1>>CN(C)CCNc1ncc2cc(-c3cc(C(=O)NC4CC4)ccc3C(F)(F)F)ccc2n1 -US20090181942A1,6,COC(=O)CCc1nnn(CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)n1>>COc1cccc([C@H]2O[C@H](CCn3nnc(CCC(=O)O)n3)c3cccn3-c3ccc(Cl)cc32)c1OC -US20130203758A1,6,CC(C)(CNC(=O)OC(C)(C)C)CNC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)c(F)c1>>CC(C)(CN)CNC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)c(F)c1 -US08569508B2,3,CC(=O)c1ccccc1C.C[Mg+]>>Cc1ccccc1C(C)(C)O -US20130150381A1,6,CCOC(=O)C(C)(C)Sc1ccccc1-c1ccncc1>>CC(C)(Sc1ccccc1-c1ccncc1)C(=O)O -US20140073626A1,3,CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Nc3ccc(C=O)cn3)nc12.CN(C)C(=O)CC#N>>CN(C)C(=O)C(C#N)=Cc1ccc(Nc2cnc3c(n2)c(C(=O)C(C)(C)C)cn3COCC[Si](C)(C)C)nc1 -US07498460B2,6,COC(=O)c1ccc(OCCCc2ccc(OCCCC3OCC(C)(C)CO3)cc2)c(C(=O)NC2CCCC(C(=O)OC)C2)c1>>COC(=O)c1ccc(OCCCc2ccc(OCCCC3OCC(C)(C)CO3)cc2)c(C(=O)NC2CCCC(C(=O)O)C2)c1 -US20150018547A1,7,CCOC(=O)c1cc(C(F)(F)F)oc1C>>Cc1oc(C(F)(F)F)cc1CO -US07608629B2,6,CC1CC(Oc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CCN1C(=O)OC(C)(C)C>>CC1CC(Oc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CCN1 -US08263657B2,3,C#C[Si](C)(C)C.O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(I)ccc1O>>C[Si](C)(C)C#Cc1ccc(O)c(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 -US20150105317A1,6,C[C@@H]1O[C@@H](OCCN(CCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)CC(=O)NCCCCCC(=O)OCc2ccccc2)[C@@H](O)[C@H](O)[C@@H]1O>>C[C@@H]1O[C@@H](OCCN(CCO[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)CC(=O)NCCCCCC(=O)O)[C@@H](O)[C@H](O)[C@@H]1O -US20080269209A1,1,CSc1ccc(C=O)cc1.Nc1nn(-c2ccc(F)cc2)c2c1cc(-c1cccnc1)c1cnccc12>>CSc1ccc(CNc2nn(-c3ccc(F)cc3)c3c2cc(-c2cccnc2)c2cnccc23)cc1 -US20070021452A1,1,CC(=O)c1sc(=O)[nH]c1C.CCI>>CCn1c(C)c(C(C)=O)sc1=O -US20150104384A1,2,NCc1ccccc1.O=C(O)c1ccc2nccn2c1>>O=C(NCc1ccccc1)c1ccc2nccn2c1 -US08802860B2,7,Cc1cc([N+](=O)[O-])ccc1-n1cccc(CC(=O)O)c1=O>>Cc1cc([N+](=O)[O-])ccc1-n1cccc(CCO)c1=O -US20110237791A1,3,CCCC[Sn](CCCC)(CCCC)/C(=C/[C@H]1CCC(=O)N1Cc1ccc(OC)cc1OC)c1ccc(C(C)(C)C)cc1.COc1nc(I)ccc1N>>COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(N)c(OC)n2)c(OC)c1 -US20060270724A1,8,OC(c1ccc(OC2CCCCO2)cc1)c1ncco1>>O=C(c1ccc(OC2CCCCO2)cc1)c1ncco1 -US07696225B2,1,Nc1ccsc1C(=O)Nc1ccc(OC(F)(F)F)cc1.O=Cc1ccnc2ccccc12>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1sccc1NCc1ccnc2ccccc12 -US08183262B2,3,CC(C)(C)NS(=O)(=O)c1cccc(B(O)O)c1.FC(F)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2ccnc(Cl)c2)n1>>CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)F)n3)ccn2)c1 -US20130225556A1,3,CC(C)OC(=O)C1(C(=O)OC(C)C)CC(=O)C1.CCOP(=O)(CC#N)OCC>>CC(C)OC(=O)C1(C(=O)OC(C)C)CC(=CC#N)C1 -US20150223460A1,1,CC(=O)c1ccc(O)c(C)c1.CC(C)I>>CC(=O)c1ccc(OC(C)C)c(C)c1 -US08404680B2,6,CC#CCOc1ccc(C(=O)OC)nc1>>CC#CCOc1ccc(C(=O)O)nc1 -US20050148643A1,4,CC(C)(C)c1ccc(N)c(N)c1.C[C@H](O)C(=O)O>>C[C@H](O)c1nc2ccc(C(C)(C)C)cc2[nH]1 -US20150232445A1,7,CCCOc1c(C2=CCN(C(=O)OC(C)(C)C)CC2)ccc2c1CC[C@H](C)N2C(C)=O>>CCCOc1c(C2CCN(C(=O)OC(C)(C)C)CC2)ccc2c1CC[C@H](C)N2C(C)=O -US20070060616A1,3,C#Cc1ccccc1.N#Cc1ccc2c(c1)c(Br)nn2C1CCCCO1>>N#Cc1ccc2c(c1)c(C#Cc1ccccc1)nn2C1CCCCO1 -US20100210642A1,3,C#Cc1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12.O=S(=O)(c1ccc(Br)cc1)N1CCOCC1>>O=S(=O)(c1ccc(C#Cc2cnn3c(C(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)cc1)N1CCOCC1 -US07833991B2,1,CCCN(CCC)Cc1ccc(OCc2ccc(CNCc3ncc[nH]3)cc2)cc1.O=Cc1ncc[nH]1>>CCCN(CCC)Cc1ccc(OCc2ccc(CN(Cc3ncc[nH]3)Cc3ncc[nH]3)cc2)cc1 -US05710249,7,C[C@H](C(=O)O)N(C(=O)OC(C)(C)C)c1ccc([N+](=O)[O-])cc1>>C[C@H](C(=O)O)N(C(=O)OC(C)(C)C)c1ccc(N)cc1 -US20120101134A1,6,CCOC(=O)CCCc1cc(F)cc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c1OC>>COc1c(CCCC(=O)O)cc(F)cc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 -US20130196971A1,3,Cc1nnc(-c2ccc(Br)cc2)n1C[C@@H]1CCN(C(=O)C2CC2)C1.OB(O)c1ccc(Cl)cc1Cl>>Cc1nnc(-c2ccc(-c3ccc(Cl)cc3Cl)cc2)n1C[C@@H]1CCN(C(=O)C2CC2)C1 -US07655641B2,2,CCCNCCSc1ccc(OCC(=O)OCC)c(C)c1.O=S(=O)(Cl)c1cccc(Br)c1>>CCCN(CCSc1ccc(OCC(=O)OCC)c(C)c1)S(=O)(=O)c1cccc(Br)c1 -US20150191439A1,1,CC(C)(C)c1ccc(-c2noc(CCl)n2)cc1.NC12CC3CC(CC(C3)C1)C2>>CC(C)(C)c1ccc(-c2noc(CNC34CC5CC(CC(C5)C3)C4)n2)cc1 -US20050014812A1,6,CCOC(=O)CCCOc1cc(C)c2nc(SCC)n(Cc3ccc(Cl)cc3Cl)c2c1>>CCSc1nc2c(C)cc(OCCCC(=O)O)cc2n1Cc1ccc(Cl)cc1Cl -US04003908,1,CC(C)O.CCOC(=O)c1c(C)nc2c(ncn2CC)c1Cl>>CCOC(=O)c1c(C)nc2c(ncn2CC)c1OC(C)C -US05998436,1,CNC1CNC1.Cc1cc(F)c(N)nc1-n1cc(C(=O)O)c(=O)c2cc(F)c(F)c(Cl)c21>>CNC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4nc(N)c(F)cc4C)c3c2Cl)C1 -US07713973B2,3,CCN(c1cccc(B(O)O)c1)S(C)(=O)=O.Cc1cc(Nc2nc(Cl)cc3nc(C(C)C)cn23)n[nH]1>>CCN(c1cccc(-c2cc3nc(C(C)C)cn3c(Nc3cc(C)[nH]n3)n2)c1)S(C)(=O)=O -US08097720B2,3,CCOP(=O)(CC#N)OCC.COc1cc(C=O)c(OS(=O)(=O)N(C)C)cc1OC>>COc1cc(C=CC#N)c(OS(=O)(=O)N(C)C)cc1OC -US20080176870A1,2,COC(=O)c1cc(C)n2ccnc2n1.NCc1ccc(F)c(F)c1>>Cc1cc(C(=O)NCc2ccc(F)c(F)c2)nc2nccn12 -US04130650,1,CN.ClCCOc1ccccc1C=Cc1ccccn1>>CNCCOc1ccccc1C=Cc1ccccn1 -US20090062280A1,7,CCCCNC(=O)C(C)(C)CO>>CCCCNCC(C)(C)CO -US20140155407A1,3,BrCc1ccc(-c2ccccc2)nc1.OB(O)c1cncc2ccccc12>>c1ccc(-c2ccc(Cc3cncc4ccccc34)cn2)cc1 -US08299077B2,7,O=Cc1c(Cl)cccc1-n1ccc2cc(C3CC3)cc(F)c2c1=O>>O=c1c2c(F)cc(C3CC3)cc2ccn1-c1cccc(Cl)c1CO -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(OS(=O)(=O)c3ccnn3C)cc(C)c21>>Cc1cc(OS(=O)(=O)c2ccnn2C)cc2c1C(CC(=O)O)OB2O -US04415572,7,COc1ccc(C(=O)N2CCN(c3ccc([N+](=O)[O-])c(C=CC(=O)O)c3)CC2)cc1OC>>COc1ccc(C(=O)N2CCN(c3ccc(N)c(C=CC(=O)O)c3)CC2)cc1OC -US06759408B2,3,CC1(C)OC(=O)Nc2ccc(Br)cc21.OB(O)c1ccccc1Cl>>CC1(C)OC(=O)Nc2ccc(-c3ccccc3Cl)cc21 -US06727264B1,1,ClCCCCCSc1ccccc1.O=C(Nc1cccc(C2CCNCC2)c1)C1CC1>>O=C(Nc1cccc(C2CCN(CCCCCSc3ccccc3)CC2)c1)C1CC1 -US04921856,1,O=C(O)CCC(=O)c1ccc(F)cc1.O=C1c2ccccc2C(=O)N1CCCc1c[nH]cn1>>O=C(O)CCC(=O)c1ccc(-n2cnc(CCCN3C(=O)c4ccccc4C3=O)c2)cc1 -US07452889B2,1,BrCCCCBr.OC1CCCC1>>BrCCCCOC1CCCC1 -US20110178060A1,6,CCOC(=O)C1=C(c2ccc(F)cc2)CN(Cc2ccccc2)CC1>>O=C(O)C1=C(c2ccc(F)cc2)CN(Cc2ccccc2)CC1 -US20090264445A1,6,COC(=O)[C@H](CC(C)C)N1CC(Oc2cccc(Cl)c2F)=CC1=O>>CC(C)C[C@@H](C(=O)O)N1CC(Oc2cccc(Cl)c2F)=CC1=O -US04443452,2,CN1CCC(O)CC1.O=C1Nc2ccccc2N(C(=O)Cl)c2ccccc21>>CN1CCC(OC(=O)N2c3ccccc3NC(=O)c3ccccc32)CC1 -US20150210641A1,1,C1CCC(N2CCNCC2)C1.COc1cc(F)ccc1-c1ccc(C(OS(C)(=O)=O)c2ccncc2)cc1>>COc1cc(F)ccc1-c1ccc(C(c2ccncc2)N2CCN(C3CCCC3)CC2)cc1 -US08268822B2,6,CC(C)(C)OC(=O)N1CCN(Cc2cccc(-c3ccnc(Cl)n3)c2)C(C(=O)O)C1>>O=C(O)C1CNCCN1Cc1cccc(-c2ccnc(Cl)n2)c1 -US20070197512A1,2,CC(C)(Br)C(=O)Br.Cc1cc(C)c(O)c(N)c1>>Cc1cc(C)c(O)c(NC(=O)C(C)(C)Br)c1 -US03978057,9,CNc1cc(Cl)nnc1NN>>CNc1ccnnc1NN -US20020052369A1,2,CCN.O=C1Cc2c(cccc2C(=O)O)N1>>CCNC(=O)c1cccc2c1CC(=O)N2 -US20090306102A1,6,COc1cccc(-c2nc(Nc3ccc(Cl)cc3)c3ccccc3n2)n1>>Oc1cccc(-c2nc(Nc3ccc(Cl)cc3)c3ccccc3n2)n1 -US05393730,2,CNC.O=C(Cl)c1cccnc1C(=O)c1cccc(C(F)(F)F)c1>>CN(C)C(=O)c1cccnc1C(=O)c1cccc(C(F)(F)F)c1 -US20070249670A1,6,COC(=O)C1(NC(=O)c2cc3ccccc3cc2N)CCCCC1>>Nc1cc2ccccc2cc1C(=O)NC1(C(=O)O)CCCCC1 -US20130324547A1,2,CC(C)(C)OC(=O)N1CC[C@H](N)C1.COc1ccc(C2CC(C(F)(F)F)n3nc(-c4cccc(C(=O)O)c4)cc3N2)cc1OC>>COc1ccc(C2CC(C(F)(F)F)n3nc(-c4cccc(C(=O)N[C@H]5CCN(C(=O)OC(C)(C)C)C5)c4)cc3N2)cc1OC -US06967198B2,2,CC(C)(C)OC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O.Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>CC(C)(C)OC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O -US20080132504A1,7,COc1cc(OC2CCN(C)CC2)ccc1[N+](=O)[O-]>>COc1cc(OC2CCN(C)CC2)ccc1N -US20110136821A1,2,CN1C(=O)C2(CCN(C(=O)/C=C/c3ccccc3C(F)(F)F)CC2)c2cc(C(=O)O)ccc21.NCCO>>CN1C(=O)C2(CCN(C(=O)/C=C/c3ccccc3C(F)(F)F)CC2)c2cc(C(=O)NCCO)ccc21 -US20090324581A1,3,COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(Cl)c1.OB(O)c1ccccc1>>COC(=O)c1ccc(-c2ccccc2)c(Cl)c1 -US20090181942A1,6,CCOC(=O)C[C@@H]1O[C@@H](c2cccc(OC)c2OC)c2cc(C(F)(F)F)ccc2-n2c1nnc2C(F)(F)Cl>>COc1cccc([C@@H]2O[C@@H](CC(=O)O)c3nnc(C(F)(F)Cl)n3-c3ccc(C(F)(F)F)cc32)c1OC -US20140343032A1,1,COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl.FC1CC2COCC1N2>>COC(=O)C1=C(CN2C3COCC2C(F)C3)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl -US20130079306A1,7,CCOC(=O)c1ccc2c(c1)nc1n2CCCC1>>OCc1ccc2c(c1)nc1n2CCCC1 -US20080039466A1,2,COC(=O)c1ccc(C)c(Nc2nc(-c3ccncc3)cs2)c1.N#Cc1ccc(N)cc1>>Cc1ccc(C(=O)Nc2ccc(C#N)cc2)cc1Nc1nc(-c2ccncc2)cs1 -US08674113B2,6,Cn1c(Nc2c(Cl)ccc(CNC(=O)OC(C)(C)C)c2Cl)nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(C34CNCC3C4)cc21>>Cn1c(Nc2c(Cl)ccc(CN)c2Cl)nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(C34CNCC3C4)cc21 -US09085583B2,9,COCC(C)n1c(C)c(Br)c2scnc21.N#C[Cu]>>COCC(C)n1c(C)c(C#N)c2scnc21 -US07132436B2,2,Nc1nc(-c2sccc2Cl)cs1.O=S(=O)(Cl)c1c(Cl)cc(Cl)cc1Cl>>O=S(=O)(Nc1nc(-c2sccc2Cl)cs1)c1c(Cl)cc(Cl)cc1Cl -US20120316147A1,2,Cn1c(C(C)(C)N)noc1=O.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>Cn1c(C(C)(C)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)noc1=O -US20140275080A1,6,CN(C(=O)OC(C)(C)C)c1ccc(-c2cc(Oc3ccc(NC(=O)NC(=O)C(C)(C)C)nc3)ccn2)cn1>>CNc1ccc(-c2cc(Oc3ccc(NC(=O)NC(=O)C(C)(C)C)nc3)ccn2)cn1 -US20130109682A1,7,CC(=O)O[C@H]1[C@H](OC(C)=O)C[C@H](c2ccncc2[N+](=O)[O-])O[C@@H]1C1CC1>>CC(=O)O[C@H]1C[C@@H](c2ccncc2N)O[C@@H](C2CC2)[C@@H]1OC(C)=O -US05840217,4,CC(C)(C)c1ccc(C#N)cc1.[N-]=[N+]=[N-]>>CC(C)(C)c1ccc(-c2nnn[nH]2)cc1 -US05690906,1,CCCN.COc1ccc2c(c1)CC(=O)CC2>>CCCNC1CCc2ccc(OC)cc2C1 -US20120264735A1,1,OCCN1CCOCC1.Oc1cnc2ccc(Cl)cc2c1>>Clc1ccc2ncc(OCCN3CCOCC3)cc2c1 -US20110118261A1,1,CCN[C@@H]1CCNC1.Fc1ccc(Br)cn1>>CCN[C@@H]1CCN(c2ccc(Br)cn2)C1 -US20070142351A1,1,CNN=C(c1sccc1Br)C1CCN(C(=O)OC(C)(C)C)CC1>>Cn1nc(C2CCN(C(=O)OC(C)(C)C)CC2)c2sccc21 -US06887885B2,3,CC1(C)OB(c2cncc(F)c2)OC1(C)C.Cn1ccc2c(ncn2-c2ccc(F)c(Br)c2)c1=O>>Cn1ccc2c(ncn2-c2ccc(F)c(-c3cncc(F)c3)c2)c1=O -US04716246,3,COc1cc(C=O)ccc1O.O=C1CNC(=O)N1>>COc1cc(C=C2NC(=O)NC2=O)ccc1O -US08242145B2,1,CCOC(=O)Cc1cccc(Oc2ccc(Br)cc2CBr)c1.O=C1NCCO1>>CCOC(=O)Cc1cccc(Oc2ccc(Br)cc2CN2CCOC2=O)c1 -US20110251196A1,1,CCCC(C)COc1ccc([C@H](CN)NC(=O)[C@@H](C)c2ccccc2)cc1.O=CC1CC1>>CCCC(C)COc1ccc([C@H](CNCC2CC2)NC(=O)[C@@H](C)c2ccccc2)cc1 -US04950674,1,COc1cc(C(C)=O)ccc1OCCCCl.N#CC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNC1>>COc1cc(C(C)=O)ccc1OCCCN1CCC(C(C#N)(c2ccc(F)cc2)c2ccc(F)cc2)C1 -US20120035168A1,6,COC(=O)c1cn(Cc2ccc(-c3ccccc3)cc2)nn1>>O=C(O)c1cn(Cc2ccc(-c3ccccc3)cc2)nn1 -US06936602B1,6,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3CC(C)C)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3CC(C)C)cc1 -US20050272791A1,2,CC(C)S(=O)(=O)Cl.CON(C)C(=O)c1ccc(N)c(N)c1>>CON(C)C(=O)c1ccc(N)c(NS(=O)(=O)C(C)C)c1 -US20040146462A1,2,CCCCCCCCCCCCCCCCO.CNCC(=O)O>>CCCCCCCCCCCCCCCCOC(=O)CNC -US09108936B2,6,CCOC(=O)c1c(C)cc(N2CCOCC2)cc1OC>>CCOC(=O)c1c(C)cc(N2CCOCC2)cc1O -US03962376,1,COP(OC)OC.Cc1cc(C(C)(C)C)c(O)c(C)c1CCl>>COP(=O)(Cc1c(C)cc(C(C)(C)C)c(O)c1C)OC -US20150038528A1,6,CC(C)(C)OC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(OC3CCCCC3)ccc2c1O>>CC(C)(CNC(=O)c1nc(C#N)c2cc(OC3CCCCC3)ccc2c1O)C(=O)O -US20110082300A1,3,C#CCCCOCc1ccccc1.CC(C)(C)OC(=O)NC1(/C=C/c2ccc(Br)cc2)COC(C)(C)OC1>>CC(C)(C)OC(=O)NC1(/C=C/c2ccc(C#CCCCOCc3ccccc3)cc2)COC(C)(C)OC1 -US05925630,1,C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)CBr)CC[C@@H]12.Oc1ccncc1>>C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)COc3ccncc3)CC[C@@H]12 -US20140213580A1,1,C=Cc1ccnc(Cl)c1.COCCC(=O)N1CCN(c2nc(C3CC3)c(N)cc2C#N)C[C@H]1C>>C=Cc1ccnc(Nc2cc(C#N)c(N3CCN(C(=O)CCOC)[C@H](C)C3)nc2C2CC2)c1 -US05238962,2,NCCN.O=C(O)c1ccc(Cl)cc1>>NCCNC(=O)c1ccc(Cl)cc1 -US20100048570A1,6,CCOC(=O)COc1ccc(CNC(=O)OC(C)(C)C)cc1>>CCOC(=O)COc1ccc(CN)cc1 -US20090054462A1,6,CC(=O)OC[C@H]1CC[C@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)[C@@H]1CNCc1ccccc1>>CC(=O)OC[C@H]1CC[C@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)[C@@H]1CN -US06344462B1,7,Cc1ccc([N+](=O)[O-])c(C)c1C(=O)O>>Cc1ccc([N+](=O)[O-])c(C)c1CO -US05877202,1,CC=NNc1ccc(OC)cc1.O=C(Cl)c1ccccc1>>CC=NN(C(=O)c1ccccc1)c1ccc(OC)cc1 -US20070155740A1,1,CC[C@@H](COC)n1cc(Cl)nc(Cl)c1=O.Clc1cc(Br)cc2c1NCC2>>CC[C@@H](COC)n1cc(Cl)nc(N2CCc3cc(Br)cc(Cl)c32)c1=O -US06410279B1,6,COC(=O)C1CCN1Cc1ccccc1>>O=C(O)C1CCN1Cc1ccccc1 -US04024271,1,BrCc1ccsn1.NCCN>>NCCNCc1ccsn1 -US05990102,6,COC(=O)CN1C(=O)CC1SCc1ccccc1>>O=C(O)CN1C(=O)CC1SCc1ccccc1 -US04642308,2,COc1ccc2ccc(N)nc2n1.O=C(O)c1ccccc1>>COc1ccc2ccc(NC(=O)c3ccccc3)nc2n1 -US05028610,1,Cc1cc(C)c(NC(=O)CCl)c(C)c1.Clc1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Cc1cc(C)c(NC(=O)CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)c(C)c1 -US20090318425A1,3,CC(C)(O)c1ccc(C(=O)Nc2nc3ccc(Br)nc3s2)cc1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2ccc3nc(NC(=O)c4ccc(C(C)(C)O)cc4)sc3n2)cn1 -US20070027178A1,4,Cc1ccc(Cl)cc1NN.O=C1CCNCC1>>Cc1ccc(Cl)c2c3c([nH]c12)CCNC3 -US09120749B2,3,CCN(CC)C1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)CC1.COc1cc(B2OC(C)(C)C(C)(C)O2)cc(Cl)c1O>>CCN(CC)C1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(OC)c4)cc23)CC1 -US20020028748A1,1,CO.Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(-c4sccc4CBr)c3c2)c1=O>>COCc1ccsc1-c1nsc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc12 -US20100324070A1,6,COC(=O)c1cc(-c2ccc(C)cn2)c2ncn(CC(C)C)c2c1>>Cc1ccc(-c2cc(C(=O)O)cc3c2ncn3CC(C)C)nc1 -US05202319,2,CCOC(=O)Cl.NN1CCc2ccccc2C(Oc2ccc(C(F)(F)F)cc2)C1>>CCOC(=O)NN1CCc2ccccc2C(Oc2ccc(C(F)(F)F)cc2)C1 -US20090202647A1,6,CCCN(CCc1cccs1)C1CCc2c(cccc2OC)C1>>CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1 -US20100068197A1,2,CC(Cl)OC(=O)Cl.COc1ccc(N(C)c2nc(CN)nc3ccccc23)cc1>>COc1ccc(N(C)c2nc(CNC(=O)OC(C)Cl)nc3ccccc23)cc1 -US08137583B2,6,Fc1cccc(C2CCC3(CC2)OCCO3)c1>>O=C1CCC(c2cccc(F)c2)CC1 -US20030008882A1,1,CC(C)[C@H]1CNCCN1c1cccc(Cc2ccccc2)c1.CC(C)c1ccccc1Br>>CC(C)c1ccccc1N1CCN(c2cccc(Cc3ccccc3)c2)[C@@H](C(C)C)C1 -US07638648B2,6,C#Cc1cc(NC(=O)Nc2ccc(C(=O)OCC)c(F)c2)cc2c1OC(C)(C)CC2(C)C>>C#Cc1cc(NC(=O)Nc2ccc(C(=O)O)c(F)c2)cc2c1OC(C)(C)CC2(C)C -US08183262B2,3,CC(C)(C)NS(=O)(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)s1.FC(F)(F)c1ccc(-c2cc(C(F)(F)F)nc(-c3ccnc(Cl)c3)n2)cc1>>CC(C)(C)NS(=O)(=O)c1ccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)ccn2)s1 -US20150119412A1,6,CCc1c(C(=O)OC)ccn(C2CCN(Cc3cc(C4CC4)c(C4CC4)c(F)c3OC(C)C)CC2)c1=O>>CCc1c(C(=O)O)ccn(C2CCN(Cc3cc(C4CC4)c(C4CC4)c(F)c3OC(C)C)CC2)c1=O -US20140088078A1,7,COC(=O)c1c(N)ccc2c1ncc1occc12>>COC(=O)c1c(N)ccc2c3c(cnc12)OCC3 -US07601837B2,1,O=S([O-])c1ccccc1.O=[N+]([O-])c1cccc2cc(I)cnc12>>O=[N+]([O-])c1cccc2cc(S(=O)(=O)c3ccccc3)cnc12 -US20130217666A1,3,C#C[C@]1(O)CCN(C)C1=O.NC(=O)c1nc2n(c1COc1ccccc1Cl)CCOc1ccc(Br)cc1-2>>CN1CC[C@@](O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)c(COc4ccccc4Cl)n2CCO3)C1=O -US20070049593A1,1,COC(=O)c1ccc2c(C3CCCCC3)c(-c3cccn3C(=O)OC(C)(C)C)[nH]c2c1.ClCCCBr>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cccn3C(=O)OC(C)(C)C)n(CCCCl)c2c1 -US20110112151A1,1,Cc1cc(C)c(C(=O)CBr)c(C)c1.Cn1ccnc1S>>Cc1cc(C)c(C(=O)CSc2nccn2C)c(C)c1 -US20110251238A1,1,C=CCBr.Oc1ccc(CCl)c2cccnc12>>C=CCOc1ccc(CCl)c2cccnc12 -US07825256B2,2,CCOC(=O)CC(NCCN(Cc1ccc2c(c1)OCO2)C(=O)OC(C)(C)C)c1cc(C)nc(-n2ccnc2)n1.CN>>CNC(=O)CC(NCCN(Cc1ccc2c(c1)OCO2)C(=O)OC(C)(C)C)c1cc(C)nc(-n2ccnc2)n1 -US20070249670A1,6,COC(=O)[C@@H]1CCCCN1C(=O)c1sc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C>>COc1ccc(-c2cc(NC(=O)Nc3c(C)cc(C)cc3C)c(C(=O)N3CCCC[C@H]3C(=O)O)s2)cc1 -US20070254877A1,6,CCOC(=O)c1ccc2[nH]c3c(c2c1)CCCc1cn[nH]c1-3>>O=C(O)c1ccc2[nH]c3c(c2c1)CCCc1cn[nH]c1-3 -US20140065136A1,1,OC(COc1c(Cl)nc(Cl)nc1N1CCOCC1)C1CC1>>Clc1nc2c(c(N3CCOCC3)n1)OCC(C1CC1)O2 -US20150274725A1,3,CC(C)(C)OC(=O)N1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.COc1ccc(COc2ccc(Cn3cnc4cc(I)cnc43)cc2OC)cn1>>COc1ccc(COc2ccc(Cn3cnc4cc(-c5cnn(C6CCN(C(=O)OC(C)(C)C)CC6)c5)cnc43)cc2OC)cn1 -US20130059853A1,1,COCC1(CBr)COC1.COc1ccc(-c2cccc3c2CCC3=O)c(O)c1OC(F)F>>COCC1(COc2c(-c3cccc4c3CCC4=O)ccc(OC)c2OC(F)F)COC1 -US08629158B2,1,Fc1ccc(CBr)nc1.O=c1cc(O)cnn1C1CCCCO1>>O=c1cc(OCc2ccc(F)cn2)cnn1C1CCCCO1 -US20060025474A1,2,CCC(CC)(c1ccc(N)c(C)c1)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1.COC(=O)CCCC(=O)O>>CCC(CC)(c1ccc(NC(=O)CCCC(=O)OC)c(C)c1)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1 -US20130231328A1,6,CC(C)(C)OC(=O)N1CCC(COc2ncnc3sc4c(c23)[C@@H](CC(N)=O)CC4)CC1>>NC(=O)C[C@H]1CCc2sc3ncnc(OCC4CCNCC4)c3c21 -US20110021500A1,2,FC(F)(F)CNc1ccccc1.O=C(O)c1cc(Cl)ncn1>>O=C(c1cc(Cl)ncn1)N(CC(F)(F)F)c1ccccc1 -US06235771B1,2,CCOC(=O)CCN(C)Cc1ccc(N)cc1.O=C(O)C1=Cc2cc(-c3ccc(N4CCOCC4)cc3)ccc2S(=O)(=O)CC1>>CCOC(=O)CCN(C)Cc1ccc(NC(=O)C2=Cc3cc(-c4ccc(N5CCOCC5)cc4)ccc3S(=O)(=O)CC2)cc1 -US20130178459A1,3,CB1OB(C)OB(C)O1.COc1cc(Br)c2[nH]c(=O)c3sccc3c2c1-c1ccc(CNC(=O)OC(C)(C)C)cc1>>COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc(CNC(=O)OC(C)(C)C)cc1 -US03935314,7,O=[N+]([O-])c1ccc2nc(NC3=NCCN3)[nH]c2c1>>Nc1ccc2nc(NC3=NCCN3)[nH]c2c1 -US08440668B2,2,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)c(F)cc1F.FC(F)(F)c1nnc2n1CCNC2>>CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F -US20070124152A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC)c1=O.CN(CCN)S(C)(=O)=O>>CCn1c(=O)c(C(=O)NCCN(C)S(C)(=O)=O)c(O)c2ncc(Cc3ccc(F)cc3)cc21 -US06599902B2,6,O=C(NC1CC1)[C@@H]1CCCN1C(=O)OCc1ccccc1>>O=C(NC1CC1)[C@@H]1CCCN1 -US20050065178A1,1,C=O.CC(=O)c1ccc(-c2ccc(N3C[C@H]4CN[C@H]4C3)cn2)cc1>>CC(=O)c1ccc(-c2ccc(N3C[C@H]4CN(C)[C@H]4C3)cn2)cc1 -US20120134987A1,3,COc1cc(F)c(B(O)O)c(F)c1.O=C(O)c1nc(Br)ccc1F>>COc1cc(F)c(-c2ccc(F)c(C(=O)O)n2)c(F)c1 -US04927819,9,NO.O=C1Cc2ccccc2C=Cc2ccccc21>>ON=C1Cc2ccccc2C=Cc2ccccc21 -US20100204159A1,2,CN.COC(=O)[C@@H](CC(=O)O)C(C)C>>CNC(=O)C[C@H](C(=O)OC)C(C)C -US20040162321A1,6,CC(C)(CC(O)(Cn1ccc(=O)c2ccccc21)C(F)(F)F)c1cccc(C2(C)OCCO2)c1>>CC(=O)c1cccc(C(C)(C)CC(O)(Cn2ccc(=O)c3ccccc32)C(F)(F)F)c1 -US05877174,1,BrCCCBr.N#Cc1ccc(O)cc1>>N#Cc1ccc(OCCCBr)cc1 -US20100272680A1,2,C[C@@H]1OC(=O)N(C2CCNCC2)C1=O.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl>>C[C@@H]1OC(=O)N(C2CCN(C(=O)c3nc4c(C(F)(F)F)cc(-c5ccoc5)cn4c3Cl)CC2)C1=O -US04925834,8,C[C@]12CC/C(=C/F)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12>>C[C@]12CC/C(=C/F)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 -US20110092526A1,6,CC(=O)N1CC[C@@H](NC(=O)OC(C)(C)C)C1>>CC(=O)N1CC[C@@H](N)C1 -US20090137609A1,3,CCC(O)(CC)CCc1ccc(C(CC)(CC)c2ccc(B3OC(C)(C)C(C)(C)O3)c(C)c2)cc1C.COC(=O)Cc1ccc(Br)cc1>>CCC(O)(CC)CCc1ccc(C(CC)(CC)c2ccc(-c3ccc(CC(=O)OC)cc3)c(C)c2)cc1C -US07727997B2,7,CCCCNc1cc(C(=O)OC)ccc1[N+](=O)[O-]>>CCCCNc1cc(C(=O)OC)ccc1N -US20050070508A1,2,CNCCN(C)C.O=C(O)c1cc2nccc(Cl)c2s1>>CN(C)CCN(C)C(=O)c1cc2nccc(Cl)c2s1 -US20150094297A1,6,COCc1sc(N2CCOCC2)nc1CO[Si](C)(C)C(C)(C)C>>COCc1sc(N2CCOCC2)nc1CO -US08367710B2,7,COc1c(-c2cc(C(=O)O)c(C)o2)cccc1[N+](=O)[O-]>>COc1c(N)cccc1-c1cc(C(=O)O)c(C)o1 -US08158620B2,4,Brc1cccc(C2=CCOCC2)c1.O=C(OO)c1cccc(Cl)c1>>Brc1cccc(C23CCOCC2O3)c1 -US20070105819A1,8,CCCCNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)cc1)c1ccccc1S2.OO>>CCCCNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)cc1)c1ccccc1S2=O -US04691027,7,COC(=O)CCC(=O)Oc1c(C)c(C)c2c(c1C)SC(CCC(=O)OC)O2>>COC(=O)CCC1Oc2c(C)c(C)c(O)c(C)c2S1 -US20120101095A1,9,CSc1nc(-c2cccc(Cl)c2)c2c(N)c(C(=O)O)sc2n1.N>>CSc1nc(-c2cccc(Cl)c2)c2c(N)c(C(N)=O)sc2n1 -US20120245161A1,2,COCCn1cc(C(=O)O)c2c(C(=O)N3CCCC3)cccc21.O=C(NCc1ccc(F)c(C2CCNCC2)c1)C(F)(F)F>>COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)C(F)(F)F)ccc3F)CC2)c2c(C(=O)N3CCCC3)cccc21 -US20140081017A1,3,C=CCCc1ccccc1.O=C(O)c1ccc(Br)o1>>O=C(O)c1ccc(C=CCCc2ccccc2)o1 -US07888352B2,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.COCCN(C)C(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1>>COCCN(C)C(=O)N1CCN(Cc2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)CC1 -US07285558B2,3,CC(=O)Cl.Cn1cccc1C=O>>CC(=O)c1cc(C=O)n(C)c1 -US03988338,1,CC(C)CCN.CSc1nc(Cl)c2ccnc-2[nH]1>>CSc1nc(NCCC(C)C)c2ccnc-2[nH]1 -US20090325924A1,7,CCOC(=O)CC(=O)C1CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)CC(O)C1CCN(C(=O)OC(C)(C)C)CC1 -US20040198982A1,1,COc1ccc(COC(=O)C(O)CC(C)C)cc1.Cn1cc(Br)c(NC(=O)OCC(Cl)(Cl)Cl)n1>>COc1ccc(COC(=O)[C@H](CC(C)C)N(C(=O)OCC(Cl)(Cl)Cl)c2nn(C)cc2Br)cc1 -US05559141,8,OC(CCCc1ccc(F)cc1)c1cncn1Cc1ccccc1>>O=C(CCCc1ccc(F)cc1)c1cncn1Cc1ccccc1 -US20140275152A1,3,COc1ccccc1B(O)O.OCc1cccnc1Cl>>COc1ccccc1-c1ncccc1CO -US08003662B2,2,CCOC(=O)C(=O)Nc1ccc(Oc2ccnc3ccsc23)c(F)c1.Nc1cccc(F)c1>>O=C(Nc1cccc(F)c1)C(=O)Nc1ccc(Oc2ccnc3ccsc23)c(F)c1 -US04755218,2,CC(Cl)(Cl)C(=O)Cl.CC1NCCc2ccccc21>>CC1c2ccccc2CCN1C(=O)C(C)(Cl)Cl -US20110015157A1,3,C=CCC1(C(C)C)CCN(C(C)c2ccc(Br)cc2)C(=O)O1.OB(O)c1ccc(F)cc1F>>C=CCC1(C(C)C)CCN([C@@H](C)c2ccc(-c3ccc(F)cc3F)cc2)C(=O)O1 -US20040067955A1,9,CC(C)n1nc(-c2cc(C(N)=O)c(Cl)nc2-c2ccccc2)ccc1=O>>CC(C)n1nc(-c2cc(C(N)=O)cnc2-c2ccccc2)ccc1=O -US20080312226A1,2,Cn1ncc(Br)c1N.O=C(Cl)OCC(Cl)(Cl)Cl>>Cn1ncc(Br)c1NC(=O)OCC(Cl)(Cl)Cl -US20080241949A1,1,C1CNCCN1.ClC1=Nc2ccccc2Sc2ccccc21>>c1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1S2 -US08389555B2,8,COc1ccccc1N1CCN(CCCO)CC1>>COc1ccccc1N1CCN(CCC=O)CC1 -US20050250822A1,6,CC1=NOC(c2ccc(NC(=O)OC(C)(C)C)c(C)c2)(C(F)(F)F)C1>>CC1=NOC(c2ccc(N)c(C)c2)(C(F)(F)F)C1 -US20120184540A1,4,Nc1ccc(F)cc1[N+](=O)[O-].OCC(O)CO>>O=[N+]([O-])c1cc(F)cc2cccnc12 -US03966736,2,O=C(Cl)CCl.O=C1Nc2cc(Br)c(Br)cc2Nc2ncccc21>>O=C1Nc2cc(Br)c(Br)cc2N(C(=O)CCl)c2ncccc21 -US20100111875A1,2,C=CCNC.Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I>>C=CCN(C)C(=O)c1c(I)c(N)c(I)c(C(=O)Cl)c1I -US20070161681A1,6,COC(=O)[C@@H](C)Oc1ccc(C#N)c(F)c1>>C[C@@H](Oc1ccc(C#N)c(F)c1)C(=O)O -US07307099B2,2,O=S(=O)(Cl)c1ccc(F)cc1.c1ccc2[nH]ccc2c1>>O=S(=O)(c1ccc(F)cc1)n1ccc2ccccc21 -US03988467,1,N=S(c1ccccc1)c1ccccc1.O=C(Cl)CCl>>O=C(CCl)N=S(c1ccccc1)c1ccccc1 -US20080045530A1,1,BrCc1ccccc1-c1ccccc1.C=C[C@@H]1C[C@]1(NC(=O)[C@H]1CCNC1)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1>>C=C[C@@H]1C[C@]1(NC(=O)[C@H]1CCN(Cc2ccccc2-c2ccccc2)C1)C(=O)NS(=O)(=O)c1cccc(OCc2ccccc2)c1 -US06248740B1,1,Clc1ccc2nc(-c3ccccc3)nn2n1.NCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>c1ccc(-c2nc3ccc(NCCCN4CCC(OC(c5ccccc5)c5ccccc5)CC4)nn3n2)cc1 -US20080300242A1,1,COc1cc(-c2nnc(CN(C)C)o2)ccc1N.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>COc1cc(-c2nnc(CN(C)C)o2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US20070254881A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(OCc1ccccc1)N1CCC[C@@H]1CO>>Cc1ccc(S(=O)(=O)OC[C@H]2CCCN2C(=O)OCc2ccccc2)cc1 -US04350691,3,CCOC(=O)CP(=O)(OCC)OCC.O=C1CC2CCC(C1)N2Cc1ccccc1>>CCOC(=O)C=C1CC2CCC(C1)N2Cc1ccccc1 -US06610692B1,6,CC(C)(C)OC(=O)N1C[C@@H](NC(=O)OCc2ccccc2)[C@H](c2ccccn2)C1>>CC(C)(C)OC(=O)N1C[C@@H](N)[C@H](c2ccccn2)C1 -US05089506,4,CN(CCCl)CCCl.NC1=CC2=c3ccccc3=C1C2>>CN1CCN(C2=CC3=c4ccccc4=C2C3)CC1 -US06919361B2,6,CCOC(=O)CN(CCCn1c(-c2ccc(F)cc2)csc1=Nc1ccc(Cl)cc1OC)C(=O)OC(C)(C)C>>COc1cc(Cl)ccc1N=c1scc(-c2ccc(F)cc2)n1CCCN(CC(=O)O)C(=O)OC(C)(C)C -US20110009389A1,1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.Cc1ncc[nH]1>>Cc1nccn1CC1CCN(C(=O)OC(C)(C)C)CC1 -US20140315911A1,1,COC(=O)[C@@H](C)N.O=C1CCCCC1>>COC(=O)[C@@H](C)NC1CCCCC1 -US04061632,2,CCc1cc2[nH]c3c(cnc4c3cnn4CC)c(=O)n2n1.O=C(Br)c1ccccc1>>CCc1cc2n(C(=O)c3ccccc3)c3c(cnc4c3cnn4CC)c(=O)n2n1 -US20070259919A1,3,CCCC[Sn](CCCC)(CCCC)c1ncccn1.Fc1cccc(Cl)c1-c1c(Cl)cc(Cl)nc1Cl>>Fc1cccc(Cl)c1-c1c(Cl)cc(-c2ncccn2)nc1Cl -US20100173888A1,2,C[C@@H](N)CO.O=C(N[C@H]1CC[C@@H](C(=O)O)C1)c1ccc(-c2cccc(F)c2)nc1>>CC(CO)NC(=O)[C@@H]1CC[C@H](NC(=O)c2ccc(-c3cccc(F)c3)nc2)C1 -US20040067966A1,6,CCCn1c(=O)c2[nH]c(C34CCC(CCCC(=O)OC)(CC3)CC4)nc2n(CCC)c1=O>>CCCn1c(=O)c2[nH]c(C34CCC(CCCC(=O)O)(CC3)CC4)nc2n(CCC)c1=O -US07772285B2,3,CC(C)COc1ccccc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1ccccc1OCC(C)C -US20120225854A1,1,CC[C@H]1CN(C(=O)OC(C)(C)C)CCN1.OC(c1ccc(Br)cc1)(C(F)(F)F)C(F)(F)F>>CC[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 -US20050101644A1,2,CNCC1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1.O=C=Nc1ccc(F)cc1>>CN(CC1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1)C(=O)Nc1ccc(F)cc1 -US08741906B2,1,C1CNC1.CC(C)(C)c1nc(Cl)c2nnn(Cc3ccccc3Cl)c2n1>>CC(C)(C)c1nc(N2CCC2)c2nnn(Cc3ccccc3Cl)c2n1 -US20100249123A1,7,CC(C)(C#N)c1ccc([N+](=O)[O-])cc1F>>CC(C)(C#N)c1ccc(N)cc1F -US07622471B2,4,CCOC(=O)C(=O)C(C)C(=O)c1ccccc1.NNc1cccnc1>>CCOC(=O)c1nn(-c2cccnc2)c(-c2ccccc2)c1C -US20080188528A1,6,COC(=O)[C@@H](NC(=O)c1cccn(Cc2ccccc2)c1=O)c1cccc(NC(=N)NS(=O)(=O)c2c(C)c(C)c3c(c2C)CCC(C)(C)O3)c1>>Cc1c(C)c(S(=O)(=O)NC(=N)Nc2cccc([C@H](NC(=O)c3cccn(Cc4ccccc4)c3=O)C(=O)O)c2)c(C)c2c1OC(C)(C)CC2 -US04261998,2,O=C(Cl)c1ccccc1Cl.c1ccc2c(c1)CCNC2>>O=C(c1ccccc1Cl)N1CCc2ccccc2C1 -US05324725,6,COc1cc2c3c(c1)c(CCN1CCN(c4cc(C)ccn4)CC1)c(C)n3CCC2>>Cc1ccnc(N2CCN(CCc3c(C)n4c5c(cc(O)cc35)CCC4)CC2)c1 -US20150080371A1,6,CCOC(=O)COCc1cn2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1>>COc1cc(C)cc2cc(-c3c(COCC(=O)O)cn4ncnc(N)c34)sc12 -US20150080438A1,9,BrC(Br)(Br)Br.OCCCCCCC1=C(c2ccc(F)c(O)c2)CCCc2c1ccc(O)c2F>>Oc1cc(C2=C(CCCCCCBr)c3ccc(O)c(F)c3CCC2)ccc1F -US04645845,1,C=C(C)C.Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCO)O2>>Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCOC(C)(C)C)O2 -US20150191461A1,2,CS(=O)(=O)Cl.Cc1cc(Nc2nccc(C(F)F)n2)cc(-c2cnn(CCN)c2)c1>>Cc1cc(Nc2nccc(C(F)F)n2)cc(-c2cnn(CCNS(C)(=O)=O)c2)c1 -US20130005716A1,1,BrCC1CC1.COC(=O)c1cc(O)cc([N+](=O)[O-])c1>>COC(=O)c1cc(OCC2CC2)cc([N+](=O)[O-])c1 -US08067408B2,2,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)O)c1.Cc1ccc(CN)cc1Br>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(Br)c2)c1 -US20060160864A1,1,N#Cc1cc(Br)ccc1F.c1cn[nH]c1>>N#Cc1cc(Br)ccc1-n1cccn1 -US05212173,1,CC1(C)[C@H]2CC[C@@H](CCCl)[C@@H]1C2.OCCCCCO>>CC1(C)[C@H]2CC[C@@H](CCOCCCCCO)[C@@H]1C2 -US08642629B2,1,CCS(=O)(=O)c1ccc(F)cc1.Cc1c(C=O)cc2ccc(F)cc2c1O>>CCS(=O)(=O)c1ccc(Oc2c(C)c(C=O)cc3ccc(F)cc23)cc1 -US20140315886A1,1,CN.Oc1nc(-c2cccnc2)nc2cc(F)c(Br)cc12>>CNc1nc(-c2cccnc2)nc2cc(F)c(Br)cc12 -US05712255,1,ClC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H]1OCc1ccccc1.O=[N+]([O-])c1cc2nc(Cl)[nH]c2cc1[N+](=O)[O-]>>O=[N+]([O-])c1cc2nc(Cl)n([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c2cc1[N+](=O)[O-] -US04745116,6,COC(=O)c1cc(OCc2ccccc2)cc(C)c1C(=O)OC>>COC(=O)c1c(C)cc(OCc2ccccc2)cc1C(=O)O -US20060189661A1,6,CC(C)(C)OC(=O)c1ccc(-c2noc(-c3cc(F)cc(C#N)c3)n2)nc1>>N#Cc1cc(F)cc(-c2nc(-c3ccc(C(=O)O)cn3)no2)c1 -US20100179109A1,2,COC(=O)Cl.Cc1cccc(Oc2c(F)cccc2C(O)(CCCN)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1>>COC(=O)NCCCC(O)(c1cccc(F)c1Oc1cccc(C)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20090005370A1,2,COC(=O)c1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C(F)(F)F)c2)cc1.NCC(F)(F)F>>O=C(NCC(F)(F)F)c1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C(F)(F)F)c2)cc1 -US20140066455A1,2,CCOC(=O)c1ccc(N2C[C@H](C)N(C)[C@H](C)C2)cc1.COc1cc(COc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(COc2cc(NC(=O)c3ccc(N4C[C@H](C)N(C)[C@H](C)C4)cc3)[nH]n2)cc(OC)c1 -US06870055B2,6,COc1ccc2c(=O)n(CCNC(=O)OC(C)(C)C)c(CN(C)C)c(-c3ccccc3)c2c1>>COc1ccc2c(=O)n(CCN)c(CN(C)C)c(-c3ccccc3)c2c1 -US20150044366A1,1,C=Cc1ccc(CCl)cc1.CCCCCCCCCCCCN(C)C>>C=Cc1ccc(C[N+](C)(C)CCCCCCCCCCCC)cc1 -US20140343053A1,9,Fc1cccc(Br)n1.NN>>NNc1cccc(Br)n1 -US06369060B1,2,Cc1ncccc1Oc1ccc(N)cn1.O=C(Cl)Oc1ccccc1>>Cc1ncccc1Oc1ccc(NC(=O)Oc2ccccc2)cn1 -US20120101136A1,1,BrCCCCBr.CCc1cc(O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1>>CCc1cc(OCCCCBr)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 -US20150094328A1,1,COc1ccc(CBr)cc1F.Cc1ccnc2c(C(=O)N[C@H]3CCCC[C@@H]3O)c[nH]c12>>COc1ccc(Cn2cc(C(=O)N[C@H]3CCCC[C@@H]3O)c3nccc(C)c32)cc1F -US20130237537A1,2,Nc1ccccc1.O=C(O)c1cc(Br)ccn1>>O=C(Nc1ccccc1)c1cc(Br)ccn1 -US07625901B2,6,O=C(CN1C(=O)CS(=O)C[C@H]1c1cc(F)cc(F)c1)OCc1ccccc1>>O=C(O)CN1C(=O)CS(=O)C[C@H]1c1cc(F)cc(F)c1 -US05302602,6,COC(=O)c1ccc2c(c1)C(SCCN1CCN(c3ccccc3)CC1)c1ccccc1CO2>>O=C(O)c1ccc2c(c1)C(SCCN1CCN(c3ccccc3)CC1)c1ccccc1CO2 -US20070010526A1,2,COc1ccc(C(=O)Cl)cc1.COc1ccc(N2CCN(C)CC2)c2c1CCN(C(=O)CCCN)C2>>COc1ccc(C(=O)NCCCC(=O)N2CCc3c(OC)ccc(N4CCN(C)CC4)c3C2)cc1 -US06537948B1,1,Clc1nccc(OCc2ccccc2)n1.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(O)c(Cl)cc2F)c1=O>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3nccc(OCc4ccccc4)n3)c(Cl)cc2F)c1=O -US20100120741A1,1,CN1CCNCC1.ClC1=Nc2ccc(Cl)cc2N2CCN=C12>>CN1CCN(C2=Nc3ccc(Cl)cc3N3CCN=C23)CC1 -US06946468B1,7,COC(=O)[C@H](CCSC)NC(=O)c1ccc([N+](=O)[O-])cc1C#Cc1ccc(F)cc1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(N)cc1C#Cc1ccc(F)cc1 -US07541370B2,6,CC(C)(C)OC(=O)N1CCN(c2cccc3c2ccn3S(=O)(=O)c2ccccc2)CC1>>O=S(=O)(c1ccccc1)n1ccc2c(N3CCNCC3)cccc21 -US20150239900A1,6,CC(=O)OCc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)c2cc(Cl)c(Br)c(F)c2n1>>CC(C)(C)OC(=O)N1CCN(c2nc(CO)nc3c(F)c(Br)c(Cl)cc23)CC1 -US06194454B1,7,Cc1cc([N+](=O)[O-])cc(C#N)c1Oc1ccc(O)c(C(C)C)c1>>Cc1cc(N)cc(C#N)c1Oc1ccc(O)c(C(C)C)c1 -US20050137240A1,2,CCC(=O)Cl.NCC1CCC(Nc2nc3c(s2)CCOc2ccccc2-3)CC1>>CCC(=O)NCC1CCC(Nc2nc3c(s2)CCOc2ccccc2-3)CC1 -US04988813,3,C#Cc1ccc(C(=O)N[C@@H](CCC(=O)OCC)C(=O)OCC)cc1.CC(C)(C)C(=O)Nc1nc(O)c2cc(Br)cnc2n1>>CCOC(=O)CC[C@H](NC(=O)c1ccc(C#Cc2cnc3nc(NC(=O)C(C)(C)C)nc(O)c3c2)cc1)C(=O)OCC -US08003649B2,1,CS(=O)(=O)c1cccc(C=O)c1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>CS(=O)(=O)c1cccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)c1 -US08476434B2,3,Clc1ccnc(Cl)n1.OB(O)c1cccnc1Cl>>Clc1nccc(-c2cccnc2Cl)n1 -US20130172354A1,1,N[C@H]1CC[C@H](N)CC1.Nc1ncc(-c2cc(F)ncc2Cl)nc1NCC1CCOCC1>>Nc1ncc(-c2cc(N[C@@H]3CC[C@@H](N)CC3)ncc2Cl)nc1NCC1CCOCC1 -US20120208814A1,1,CC(=O)N1c2ccc(-c3cn(CCO[Si](C)(C)C(C)(C)C)nn3)cc2[C@H](N)C[C@@H]1C.Cc1ccc(Br)nc1>>CC(=O)N1c2ccc(-c3cn(CCO[Si](C)(C)C(C)(C)C)nn3)cc2[C@H](Nc2ccc(C)cn2)C[C@@H]1C -US20010012846A1,7,CC[C@H](NC(=O)c1c(N2CCC[C@H]2C(=O)OC)c(-c2ccccc2)nc2ccccc12)c1ccccc1>>CC[C@H](NC(=O)c1c(N2CCC[C@H]2CO)c(-c2ccccc2)nc2ccccc12)c1ccccc1 -US20150038528A1,2,COC(=O)C1(CN)CCC1.COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O>>COC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCC1 -US20100056527A1,6,Cc1cc(C(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12>>Cc1cc(C(=O)N[C@@H]2CCNC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 -US05614634,6,CCCCCCCCC(O)/C=C/c1cccc(C(=O)c2cccc(C(=O)OC)c2)n1>>CCCCCCCCC(O)/C=C/c1cccc(C(=O)c2cccc(C(=O)O)c2)n1 -US20100063091A1,1,COCCBr.COCCCc1cc(O)cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1>>COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)cc(OCCOC)c1 -US05849911,6,CC(C)(C)OC(=O)NN(Cc1ccc(-c2cnccn2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)C(F)(F)F>>CC(C)(C)OC(=O)NN(Cc1ccc(-c2cnccn2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1 -US04350822,7,O=C(O)CCCCCc1ccccc1>>OCCCCCCc1ccccc1 -US07576080B2,2,Nc1cccc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1.O=C(Cl)C1CC1>>O=C(Nc1cccc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1)C1CC1 -US20130245064A1,6,CCOC(=O)c1ccc(Oc2ccc(Cl)c(Cl)c2)cc1>>O=C(O)c1ccc(Oc2ccc(Cl)c(Cl)c2)cc1 -US08969394B2,2,COC(=O)c1ccc(C2([NH3+])CC2)cc1.Cc1sc(C)c(C(=O)O)c1Cc1ccc(C(F)(F)F)cc1>>COC(=O)c1ccc(C2(NC(=O)c3c(C)sc(C)c3Cc3ccc(C(F)(F)F)cc3)CC2)cc1 -US08093385B2,1,CCOC(=O)CCCOc1cccc(CCCCCCBr)c1CCC(=O)OCC.Oc1cc(Br)cc(Br)c1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(Br)c2)c1CCC(=O)OCC -US20120316161A1,3,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.CCc1ccc(B(O)O)cc1>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(CC)cc1 -US20140243313A1,6,CC(C)(C)OC(=O)N1CC2(CN(CC(O)CN3c4ccccc4Sc4ccc(C(F)(F)F)cc43)C2)C1>>OC(CN1CC2(CNC2)C1)CN1c2ccccc2Sc2ccc(C(F)(F)F)cc21 -US20100016344A1,1,CC(C)(C)OC(=O)NCCN.Nc1nccc(Cl)n1>>CC(C)(C)OC(=O)NCCNc1ccnc(N)n1 -US06465505B1,1,CCc1cccc(CC)c1C=O.Cc1nc2cccc(N)c2[nH]1>>CCc1cccc(CC)c1CNc1cccc2nc(C)[nH]c12 -US08394986B2,7,COc1ccc(F)cc1Oc1ccc([N+](=O)[O-])cc1Cl>>COc1ccc(F)cc1Oc1ccc(N)cc1Cl -US20110263571A1,1,CC[C@@H]1COC(=O)N1.Cc1cnc(N2CCN(C(=O)c3ccc(Br)c(F)c3)CC2)c(C)c1>>CC[C@@H]1COC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cc1F -US20150119392A1,1,CC(C)(O)CCN(Cc1ccccc1)Cc1ccccc1.CI>>COC(C)(C)CCN(Cc1ccccc1)Cc1ccccc1 -US05360800,7,CCCc1c(C=O)ncn1S(=O)(=O)N(C)C>>CCCc1c(CO)ncn1S(=O)(=O)N(C)C -US08158820B2,3,CC(=O)N(Cc1ccccc1)c1ncc(Br)cn1.OB(O)c1cc(Cl)ccc1O>>CC(=O)N(Cc1ccccc1)c1ncc(-c2cc(Cl)ccc2O)cn1 -US20140371199A1,6,CC1(NC(=O)OC(C)(C)C)CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(Cl)cc5)n4c3)cc2)CC1>>CC1(N)CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(Cl)cc5)n4c3)cc2)CC1 -US20140206662A1,7,O=[N+]([O-])c1ccc2nc(-c3ccc(Cl)cc3)c(CO)n2c1>>Nc1ccc2nc(-c3ccc(Cl)cc3)c(CO)n2c1 -US20140243336A1,1,CC(C)(C)OC(=O)NC(CNC(=O)OCc1ccccc1)COS(C)(=O)=O.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)NC(CN=[N+]=[N-])CNC(=O)OCc1ccccc1 -US07300932B2,1,CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1CCCO.CI>>CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1CCCOC -US20070015744A1,1,CN(CCO)C(=O)OC(C)(C)C.Oc1cccc2[nH]ccc12>>CN(CCOc1cccc2[nH]ccc12)C(=O)OC(C)(C)C -US07482455B2,6,COc1ccc2cc(C(=O)O)c(NCCCNC(=O)OC(C)(C)C)nc2c1>>COc1ccc2cc(C(=O)O)c(NCCCN)nc2c1 -US20090082379A1,7,O=C(c1ccc([N+](=O)[O-])cc1)N1CCCC1>>Nc1ccc(C(=O)N2CCCC2)cc1 -US08791102B2,2,O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccc(F)cc2Cl)CN1.O=C(O)Cn1nccn1>>O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccc(F)cc2Cl)CN1C(=O)Cn1nccn1 -US08288371B2,2,Cc1nnc([C@H]2CCCN2)n1Cc1ccc(Cl)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>Cc1nnc([C@H]2CCCN2C(=O)Nc2ccc(C(F)(F)F)cc2)n1Cc1ccc(Cl)cc1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4cccnn4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cccnn4)cc2)CCN3CC(C)C)cc1 -US20110245264A1,6,CCCC(C)COc1ccc([C@H](CO)NC(=O)OC(C)(C)C)cc1>>CCCC(C)COc1ccc([C@@H](N)CO)cc1 -US20080027050A1,2,CCOC(=O)c1nc2sc(C)cc2c(=O)[nH]1.COc1cccc(CN)c1>>COc1cccc(CNC(=O)c2nc3sc(C)cc3c(=O)[nH]2)c1 -US20070105890A1,2,C1COCCN1.Cn1c(=O)c2c(nc(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)n2Cc2ccccc2Cl)c2cc(C(=O)O)ccc21>>Cn1c(=O)c2c(nc(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)n2Cc2ccccc2Cl)c2cc(C(=O)N3CCOCC3)ccc21 -US20110306587A1,6,CC(C)(C)OC(=O)N1CCC(c2ncccc2-c2ccccc2)CC1>>c1ccc(-c2cccnc2C2CCNCC2)cc1 -US06469039B1,2,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CN(C)c1ccc(C(=N)N)cc1)n2C)c1ccccn1.O=C(Cl)c1ccccc1>>CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CN(C)c1ccc(C(=N)NC(=O)c3ccccc3)cc1)n2C)c1ccccn1 -US20110166129A1,6,CCOC(=O)c1nc(-c2ccc(N3CCOCC3)nc2)sc1NC(=O)OC(C)(C)C>>CCOC(=O)c1nc(-c2ccc(N3CCOCC3)nc2)sc1N -US06982348B2,6,CC(C)(C)OC(=O)NC(Cc1cnc(C(F)(F)F)s1)C(O)c1ccc(F)cc1>>NC(Cc1cnc(C(F)(F)F)s1)C(O)c1ccc(F)cc1 -US04952588,2,CCOC(=O)C1=C(O)c2ccccc2N(c2ccccc2)C1.Nc1ccccc1>>O=C(Nc1ccccc1)C1=C(O)c2ccccc2N(c2ccccc2)C1 -US07776910B2,1,COC(=O)CBr.Cc1cc(S(=O)(=O)c2cccc(F)c2)ccc1C1CCNC1>>COC(=O)CN1CCC(c2ccc(S(=O)(=O)c3cccc(F)c3)cc2C)C1 -US20100063047A1,1,Cc1csc2ncnc(CCN)c12.OB(O)c1ccc(Cl)cc1>>Cc1csc2ncnc(CCNc3ccc(Cl)cc3)c12 -US07186724B2,6,CC(C)(C)OC(=O)C1(CCN2CCN(c3csc4cc(C(F)(F)F)ccc34)CC2)CC1>>O=C(O)C1(CCN2CCN(c3csc4cc(C(F)(F)F)ccc34)CC2)CC1 -US20140303177A1,1,Clc1ncnc2[nH]ccc12.N#CC1(c2ccc(Cl)cc2)CCNCC1>>N#CC1(c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 -US20090143352A1,3,CN(C)C(=O)c1cc(I)cc(F)c1N.COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(B3OC(C)(C)C(C)(C)O3)cc12>>COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(-c3cc(F)c(N)c(C(=O)N(C)C)c3)cc12 -US20120101100A1,3,CCNC(=O)Nc1cc(-c2nc(-c3cccc(OC)n3)cs2)c(B(O)O)cn1.COC(=O)c1sc(Cl)nc1-c1ncnn1C>>CCNC(=O)Nc1cc(-c2nc(-c3cccc(OC)n3)cs2)c(-c2nc(-c3ncnn3C)c(C(=O)OC)s2)cn1 -US20150018422A1,3,CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)c(OS(=O)(=O)C(F)(F)F)c2)c1)C1CC1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)c(-c3ccc(C(F)(F)F)cc3)c2)c1)C1CC1 -US20050215581A1,2,Cc1nc2c(N)nc3ccccc3c2n1CCOCCN.O=C=NC1CCCCC1>>Cc1nc2c(N)nc3ccccc3c2n1CCOCCNC(=O)NC1CCCCC1 -US08003785B2,2,COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C.NCCCN1CCCC1=O>>COc1cc(C(=O)NCCCN2CCCC2=O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US08053440B2,3,C=C[Sn](CCCC)(CCCC)CCCC.COCOc1ccc(C=O)cc1Br>>C=Cc1cc(C=O)ccc1OCOC -US07276516B2,3,O=C(NCc1ccc(F)cc1)c1ccc(S(=O)(=O)n2cc(I)c3ccccc32)cc1.OB(O)c1ccccc1Cl>>O=C(NCc1ccc(F)cc1)c1ccc(S(=O)(=O)n2cc(-c3ccccc3Cl)c3ccccc32)cc1 -US20100160256A1,1,CC[Si](CC)(CC)O[C@@H](CI)c1ccc(F)c(NS(C)(=O)=O)c1.OCCNCc1ccccc1>>CC[Si](CC)(CC)O[C@@H](CN(CCO)Cc1ccccc1)c1ccc(F)c(NS(C)(=O)=O)c1 -US20090023718A1,1,CNCC(=O)OC(C)(C)C.COC(=O)CCCCCBr>>COC(=O)CCCCCN(C)CC(=O)OC(C)(C)C -US20040067955A1,9,CC(C)n1nc(-c2ccc(Cl)nc2-c2ccccc2)ccc1=O.NN>>CC(C)n1nc(-c2ccc(NN)nc2-c2ccccc2)ccc1=O -US05541229,6,CCCCCCCCCCCCNC(=O)N(C)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4C(=O)OC(C)(C)C)cc3)c2c1>>CCCCCCCCCCCCNC(=O)N(C)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4C(=O)O)cc3)c2c1 -US20110319385A1,6,Cc1cc2c(cc1C(=O)N1CCc3cc(Cl)ccc31)[nH]c(=O)c1cnc([C@@H]3CC[C@@H](C(=O)OCc4ccccc4)CC3)n12>>Cc1cc2c(cc1C(=O)N1CCc3cc(Cl)ccc31)[nH]c(=O)c1cnc([C@@H]3CC[C@@H](C(=O)O)CC3)n12 -US05616586,7,CCOC(=O)C=CC1CCC2CC=CC=C2N1C(=O)C(=O)OCC>>CCOC(=O)CCC1CCC2CC=CC=C2N1C(=O)C(=O)OCC -US20080064678A1,3,C=Cc1ccc(F)c(OC)c1.COc1ccc(COC(=O)c2cc(OCc3ccc(OC)cc3)ccc2I)cc1>>COc1ccc(COC(=O)c2cc(OCc3ccc(OC)cc3)ccc2/C=C/c2ccc(F)c(OC)c2)cc1 -US20130131075A1,2,CCOc1ccc(Nc2ccc(CN)cc2)c(C(F)(F)F)c1.O=C(NC1(C(=O)O)CC1)c1cncnc1>>CCOc1ccc(Nc2ccc(CNC(=O)C3(NC(=O)c4cncnc4)CC3)cc2)c(C(F)(F)F)c1 -US20090176783A1,6,CCOC(=O)C(C)(C)c1ccc(-c2ccc(C(F)(F)F)cn2)cc1>>CC(C)(C(=O)O)c1ccc(-c2ccc(C(F)(F)F)cn2)cc1 -US20140315801A1,1,CC(C)(C)OC(=O)N1CCN(CCn2cnc(-c3cc4nccc(Cl)c4s3)c2)CC1.Nc1ccc(O)c(F)c1>>CC(C)(C)OC(=O)N1CCN(CCn2cnc(-c3cc4nccc(Oc5ccc(N)cc5F)c4s3)c2)CC1 -US20020082278A1,3,O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.c1ccc(COCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>C(=C\c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)\CCOCc1ccccc1 -US03959309,7,Cn1c2c(c3ccccc31)CC(OC(=O)c1ccccc1)CC2>>Cn1c2c(c3ccccc31)CC(O)CC2 -US20040152597A1,7,COC(=O)COc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1[N+](=O)[O-]>>COC(=O)COc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1N -US20040266826A1,3,CC1(C)OB(c2ccc3sccc3c2)OC1(C)C.C[Si](C)(C)CCOC(=O)C[C@]1(c2ccc(Br)s2)CCCCS1(=O)=O>>C[Si](C)(C)CCOC(=O)C[C@]1(c2ccc(-c3ccc4sccc4c3)s2)CCCCS1(=O)=O -US06703425B2,6,CC(CNS(=O)(=O)C(C)C)c1ccc(CCCNC(=O)OCc2ccccc2)cc1>>CC(CNS(=O)(=O)C(C)C)c1ccc(CCCN)cc1 -US05151507,3,C#CCNC(=O)C(F)(F)F.Nc1nc(=O)n(COCCO)cc1I>>Nc1nc(=O)n(COCCO)cc1C#CCNC(=O)C(F)(F)F -US08455479B2,1,CC(C)(C)OC(=O)N1CC(=O)Nc2ccccc2C1.CI>>CN1C(=O)CN(C(=O)OC(C)(C)C)Cc2ccccc21 -US20070259881A1,6,CC(C)Cn1c(CN2C(=O)c3ccccc3C2=O)nc2c(N)nc3cccnc3c21>>CC(C)Cn1c(CN)nc2c(N)nc3cccnc3c21 -US20150210687A1,2,CS(=O)(=O)Cl.OCc1c(Cl)cccc1C(F)(F)F>>CS(=O)(=O)OCc1c(Cl)cccc1C(F)(F)F -US04576957,6,O=C1c2ccccc2C(=O)N1CCCCCn1ccnc1>>NCCCCCn1ccnc1 -US20120289522A1,3,CCOC(=O)[C@@H]1C[C@H]1c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cc1noc(-c2ccc(Br)cc2)c1CSCCc1ccccc1>>CCOC(=O)[C@@H]1C[C@H]1c1ccc(-c2ccc(-c3onc(C)c3CSCCc3ccccc3)cc2)cc1 -US20140175406A1,1,Clc1ccc2scc(-n3c4ccccc4c4ccccc43)c2c1.c1ccc2c(c1)[nH]c1ccccc12>>c1ccc2c(c1)c1ccccc1n2-c1ccc2scc(-n3c4ccccc4c4ccccc43)c2c1 -US20070105908A1,2,COC(=O)c1ccccc1S(=O)(=O)/N=c1\sc(CCN)cn1Cc1cccc2ccccc12.O=C(O)c1ccncc1>>COC(=O)c1ccccc1S(=O)(=O)/N=c1\sc(CCNC(=O)c2ccncc2)cn1Cc1cccc2ccccc12 -US06156758,1,COc1cc2nc(Cl)nc(N)c2cc1OC.Nc1ccc(OCc2ccccc2)cc1>>COc1cc2nc(Nc3ccc(OCc4ccccc4)cc3)nc(N)c2cc1OC -US05559266,1,CC(=O)Nc1c(I)c(C(=O)[O-])c(I)c(N(C)C(C)=O)c1I.CCOC(=O)OC(C)Cl>>CCOC(=O)OC(C)OC(=O)c1c(I)c(NC(C)=O)c(I)c(N(C)C(C)=O)c1I -US09108983B2,6,COc1cc(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)c(-c2cc(C(=O)N(c3ccccc3)c3cnc4c(ccn4C)c3)c(C)n2C)cc1F>>Cc1c(C(=O)N(c2ccccc2)c2cnc3c(ccn3C)c2)cc(-c2cc(F)c(O)cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n1C -US20090018134A1,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.O=S(=O)(c1ccncc1)C1(c2cc(N3CCOCC3)nc(Cl)n2)CC1>>Nc1ccc(-c2nc(N3CCOCC3)cc(C3(S(=O)(=O)c4ccncc4)CC3)n2)cc1 -US20120190635A1,1,CC(=O)OC1C(F)OC(C)CC1N(C)C.OC1CCCCCCCCCCCCC1>>CC(=O)OC1C(OC2CCCCCCCCCCCCC2)OC(C)CC1N(C)C -US20150246906A1,1,CC(C)(C)OC(=O)NCC1CCNC1.FC(F)(F)c1ccc(Br)cc1>>CC(C)(C)OC(=O)NCC1CCN(c2ccc(C(F)(F)F)cc2)C1 -US04021479,7,O=C(O)/C=C/C(O)c1ccc(-c2ccc(F)c(F)c2)cc1>>O=C(O)CCC(O)c1ccc(-c2ccc(F)c(F)c2)cc1 -US20070082907A1,1,Cc1cc(O)ccc1OCc1ccccc1.N#Cc1cccc(F)c1>>Cc1cc(Oc2cccc(C#N)c2)ccc1OCc1ccccc1 -US06399620B1,2,CCOC(=O)CCCOc1ccc(C[C@H](NC(=O)OCC23CC4CC(CC(C4)C2)C3)C(=O)OC(C)(C)C)cc1.NC1=NCCN1>>CC(C)(C)OC(=O)[C@H](Cc1ccc(OCCCC(=O)NC2=NCCN2)cc1)NC(=O)OCC12CC3CC(CC(C3)C1)C2 -US20020160398A1,8,OC(CCl)COc1ccccc1>>O=C(CCl)COc1ccccc1 -US20080275029A1,4,NC=O.Nc1cc(F)ccc1C(=O)O>>O=c1[nH]cnc2cc(F)ccc12 -US20110294779A1,2,C1COCCN1.Cn1ncc(C(=O)O)c1C(=O)Nc1cc2nc(-c3ccccc3)cn2c(N2CCOCC2)n1>>Cn1ncc(C(=O)N2CCOCC2)c1C(=O)Nc1cc2nc(-c3ccccc3)cn2c(N2CCOCC2)n1 -US20070049537A1,7,O=C1CCCC1Oc1ccc(Cc2cc([C@@]3(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1>>OC[C@H]1O[C@](O)(c2ccc(Cl)c(Cc3ccc(O[C@@H]4CCC[C@@H]4O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O -US08470828B2,2,N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1.O=C(O)c1ccc2ncccc2c1>>O=C(N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3OCC4)CC2)CC1)c1ccc2ncccc2c1 -US04363909,6,CCOC(=O)Cc1cnc(N=C2SC[C@@H]3Cc4ccccc4CN23)s1>>O=C(O)Cc1cnc(N=C2SC[C@@H]3Cc4ccccc4CN23)s1 -US05166156,7,COc1ccc2c(N3CCN(CC#N)CC3)cccc2c1>>COc1ccc2c(N3CCN(CCN)CC3)cccc2c1 -US05420132,2,CCCCNc1ccccc1.O=C(O)C1=COc2ccc(O)cc2O1>>CCCCN(C(=O)C1=COc2ccc(O)cc2O1)c1ccccc1 -US05376687,3,COc1ccc(F)c2c1C(=O)CC2.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1CCc2c(F)ccc(OC)c21 -US20110275797A1,6,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(-c2cccc(N)n2)ccc1O>>Nc1cccc(-c2ccc(O)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)O)c2)n1 -US05753664,1,Cc1ccc(C(=O)c2ccc(CBr)cc2)cc1.Cn1c(=O)c2[nH]cnc2n(C)c1=O>>Cc1ccc(C(=O)c2ccc(Cn3cnc4c3c(=O)n(C)c(=O)n4C)cc2)cc1 -US04011222,1,CN1CCNCC1.Fc1ccc2c(c1)C(Cl)Cc1ccc(C(F)(F)F)cc1S2>>CN1CCN(C2Cc3ccc(C(F)(F)F)cc3Sc3ccc(F)cc32)CC1 -US20130274260A1,3,Cc1ccccc1B(O)O.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CCl)cc1>>Cc1ccccc1Cc1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 -US08697691B2,2,C=CCN.O=C(Cl)c1ccccc1>>C=CCNC(=O)c1ccccc1 -US04545810,2,CNC.O=C(O)c1c(-c2ccccc2)c(-c2ccccc2)n[nH]c1=O>>CN(C)C(=O)c1c(-c2ccccc2)c(-c2ccccc2)n[nH]c1=O -US20100099690A1,6,CCCCCn1c(=O)n(-c2ccccc2)c(=O)c2c1ncn2Cc1ccc(OC)cc1>>CCCCCn1c(=O)n(-c2ccccc2)c(=O)c2[nH]cnc21 -US20040121965A1,2,CN[C@H](C(=O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)O)C(C)C)C(C)(C)C)C(C)(C)c1ccccc1.NCCc1ccccc1>>CN[C@H](C(=O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)NCCc1ccccc1)C(C)C)C(C)(C)C)C(C)(C)c1ccccc1 -US20120184531A1,6,CC(C)(C)OC(=O)N1CCCc2oc3ccc(S(=O)(=O)c4ccccc4)cc3c2C1>>O=S(=O)(c1ccccc1)c1ccc2oc3c(c2c1)CNCCC3 -US06821967B2,1,Cn1c(N2CCNCC2)nc2ccc(F)cc21.O=C(NCc1ccc(F)cc1)C1(CCCCBr)c2ccccc2-c2ccccc21>>Cn1c(N2CCN(CCCCC3(C(=O)NCc4ccc(F)cc4)c4ccccc4-c4ccccc43)CC2)nc2ccc(F)cc21 -US07902201B2,6,COC(=O)c1cnc(OCc2c(-c3ccc(F)cn3)noc2C)cn1>>Cc1onc(-c2ccc(F)cn2)c1COc1cnc(C(=O)O)cn1 -US20070155808A1,1,CC(C)CCNc1nc(-c2ccc(C(F)(F)F)cc2)cs1.COC(=O)CCc1ccc(OCc2ccc(CCl)cc2)cc1>>COC(=O)CCc1ccc(OCc2ccc(CN(CCC(C)C)c3nc(-c4ccc(C(F)(F)F)cc4)cs3)cc2)cc1 -US20070254881A1,6,CCOC(=O)c1cc(-c2c[nH]c(C)n2)n(-c2ccc(OC)nc2)n1>>COc1ccc(-n2nc(C(=O)O)cc2-c2c[nH]c(C)n2)cn1 -US20100278833A1,6,CC(Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O)c1ccccc1OC(F)F>>CC(Oc1cc(-n2cnc3cnc(CO)cc32)sc1C(N)=O)c1ccccc1OC(F)F -US07960374B2,7,CC1=NCCOc2c(F)cc3c(ccn3S(=O)(=O)c3ccccc3)c21>>CC1NCCOc2c(F)cc3c(ccn3S(=O)(=O)c3ccccc3)c21 -US08877780B2,2,CC(C)(C)c1ccc(C(=O)Cl)cc1.NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O>>CC(C)(C)c1ccc(C(=O)NCc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1 -US07109225B2,9,CCO[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](O)c1ccc(OCCc2nc(C(C)(C)C)oc2C)c2ccccc12>>CCO[C@@H](Cc1ccc(OCCc2nc(C(C)(C)C)oc2C)c2ccccc12)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1 -US06331637B1,2,Cc1noc(N)c1C.O=S(=O)(Cl)c1ccco1>>Cc1noc(NS(=O)(=O)c2ccco2)c1C -US08288549B2,1,N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(NCCCC[C@H](Nc1nc2ccc(Cl)cc2cc1C(=O)O)C(=O)O)OCc1ccccc1 -US08183262B2,3,Brc1csc(Br)n1.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(I)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2nc(Br)cs2)n1 -US20150099737A1,2,CC(C)(C)OC(=O)N1C2CCC1CNC2.Cc1cc(N)ncc1C(=O)O>>Cc1cc(N)ncc1C(=O)N1CC2CCC(C1)N2C(=O)OC(C)(C)C -US20040058978A1,1,CC(C)S(=O)(=O)Nc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1.CN(C)CCCl>>CC(C)S(=O)(=O)N(CCN(C)C)c1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1 -US20080176926A1,2,CCc1sc(C(=O)CCc2cc(C)c(OCCO)c(C)c2)c2c1CC(C)(C)CC2.CS(=O)(=O)Cl>>CCc1sc(C(=O)CCc2cc(C)c(OCCOS(C)(=O)=O)c(C)c2)c2c1CC(C)(C)CC2 -US20080188528A1,2,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.Cc1ccccc1C(c1ccccc1C)n1cccc(C(=O)O)c1=O>>Cc1ccccc1C(c1ccccc1C)n1cccc(C(=O)N[C@@H](CCCNC(=N)NS(=O)(=O)c2c(C)c(C)c3c(c2C)CCC(C)(C)O3)C(=O)OC(C)(C)C)c1=O -US06117875,7,O=[N+]([O-])c1cccnc1Nc1cccc(/C=C/c2cncc(/C=C/c3ccncc3)c2)c1>>Nc1cccnc1Nc1cccc(/C=C/c2cncc(/C=C/c3ccncc3)c2)c1 -US08106215B2,2,Cc1nc(C(=O)O)c(-c2ccccc2)s1.Cc1nc2sccn2c1C(=O)NC[C@H]1NC[C@@H]2CCC[C@H]12>>Cc1nc(C(=O)N2C[C@@H]3CCC[C@@H]3[C@H]2CNC(=O)c2c(C)nc3sccn23)c(-c2ccccc2)s1 -US20080058522A1,7,N/C(=C\C(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F>>N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F -US20120316147A1,6,Cc1nc([C@H](CC2CC2)NC(=O)OC(C)(C)C)no1>>Cc1nc([C@@H](N)CC2CC2)no1 -US20100081680A1,1,NS(=O)(=O)c1ccc(C(F)(F)F)cc1.O=Cc1ccccc1I>>O=S(=O)(/N=C/c1ccccc1I)c1ccc(C(F)(F)F)cc1 -US20100261727A1,1,COc1ccc2cc(-c3ccnc(Cl)n3)sc2c1.OCCCF>>COc1ccc2cc(-c3ccnc(OCCCF)n3)sc2c1 -US05300642,7,O=C1c2ncccc2-c2cccnc21>>c1cnc2c(c1)-c1cccnc1C2 -US20080058515A1,7,COc1cc([N+](=O)[O-])ccc1OCCN(C(C)C)C(C)C>>COc1cc(N)ccc1OCCN(C(C)C)C(C)C -US20100234351A1,6,CC(C)(C)OC(=O)N(CCS(C)(=O)=O)C1CC1>>CS(=O)(=O)CCNC1CC1 -US20050209241A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1nc(-c2ccc(Br)cc2)no1>>Cc1nc(-c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2)no1 -US20130197012A1,3,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc(Cl)c(C(=O)OC)c3)cc12.NC(=O)c1ccccc1B(O)O>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc(-c4ccccc4C(N)=O)c(C(=O)OC)c3)cc12 -US07737166B2,3,Cc1nc2c(C#N)c(C)c(Br)c(F)c2o1.OB(O)c1ccccc1>>Cc1nc2c(C#N)c(C)c(-c3ccccc3)c(F)c2o1 -US20090023725A1,3,Brc1ccc2c(-c3ccc(N4CCOCC4)nc3)n[nH]c2c1.CCNC(=O)c1ccc(C)c(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)c1ccc(C)c(-c2ccc3c(-c4ccc(N5CCOCC5)nc4)n[nH]c3c2)c1 -US07176212B2,1,CCc1ccccc1Nc1ccnc(Cl)n1.CN(C)CC(O)COc1ccc(N)cc1>>CCc1ccccc1Nc1ccnc(Nc2ccc(OCC(O)CN(C)C)cc2)n1 -US20120165548A1,6,COc1ccccc1OCC(F)(F)F>>Oc1ccccc1OCC(F)(F)F -US04432993,1,COC(=O)CCCOc1ccc(CC(C)=O)cc1.NCC(O)c1cc2ccccc2o1>>COC(=O)CCCOc1ccc(CC(C)NCC(O)c2cc3ccccc3o2)cc1 -US20090029991A1,2,CC(=O)OC(C)=O.Nc1ccccc1NC(=O)c1ccc(C2CCNCC2)cc1>>CC(=O)N1CCC(c2ccc(C(=O)Nc3ccccc3N)cc2)CC1 -US20110218189A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Cn2c(-c3c(Cl)cccc3Cl)cc3cnc(NCc4ccc(O)cc4)nc32)C1>>Oc1ccc(CNc2ncc3cc(-c4c(Cl)cccc4Cl)n(C[C@@H]4CCCNC4)c3n2)cc1 -US05502065,3,CCCC[Sn](CCCC)(CCCC)c1ccc(C(N)=O)cc1.O=C(OCc1ccccc1)N1CCC[C@@H]1Cc1c[nH]c2ccc(Br)cc12>>NC(=O)c1ccc(-c2ccc3[nH]cc(C[C@H]4CCCN4C(=O)OCc4ccccc4)c3c2)cc1 -US20150018345A1,1,CI.C[C@@H](N[S@@](=O)C(C)(C)C)c1cc(Cl)cc(C(F)(F)F)c1>>C[C@H](c1cc(Cl)cc(C(F)(F)F)c1)N(C)[S@@](=O)C(C)(C)C -US20100121075A1,3,C=Cc1ccccc1.Ic1ccccc1>>C(=Cc1ccccc1)c1ccccc1 -US20150065534A1,2,CC(C)(C)OC(=O)NCCCOc1cccc(C(=O)O)c1.COC(=O)[C@H](CN)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C>>COC(=O)[C@H](CNC(=O)c1cccc(OCCCNC(=O)OC(C)(C)C)c1)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C -US06117888,1,CCOC(=O)Cn1c(C)cc(S(=O)(=O)CCCl)c(N)c1=O>>CCOC(=O)Cn1c(C)cc2c(c1=O)NCCS2(=O)=O -US20150025237A1,7,O=C1OC[C@@H]2C[C@]12c1cccc(F)c1>>OC[C@@H]1C[C@@]1(CO)c1cccc(F)c1 -US20150111877A1,2,CC(C)(C)OC(=O)Nc1cnc2c(c1)NCC(C(C)(C)O[SiH2]C(C)(C)C)C2.Cc1nn(C(F)F)cc1S(=O)(=O)Cl>>Cc1nn(C(F)F)cc1S(=O)(=O)N1CC(C(C)(C)O[SiH2]C(C)(C)C)Cc2ncc(NC(=O)OC(C)(C)C)cc21 -US05210209,1,CC(=O)CCl.Sc1nc2ccccc2[nH]1>>CC(=O)CSc1nc2ccccc2[nH]1 -US20030139464A1,6,COC(=O)C(CN1C(=O)c2cccc(O)c2C1=O)C1(C)OCCO1>>COC(=O)C(CN1C(=O)c2cccc(O)c2C1=O)C(C)=O -US20130131068A1,2,COC(=O)c1nc(C(F)(F)F)n2c1CNCC2.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>COC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)c1cc(Cc3n[nH]c(=O)c4ccccc34)ccc1F)CC2 -US06083943,1,COC(=O)CN.O=Cc1ccccc1>>COC(=O)CN=Cc1ccccc1 -US20090149439A1,2,COc1ccc(S(=O)(=O)C(c2cnc(C(=O)O)cc2C)c2cc(F)ccc2F)cc1.NCCO>>COc1ccc(S(=O)(=O)C(c2cnc(C(=O)NCCO)cc2C)c2cc(F)ccc2F)cc1 -US20120058989A1,8,CC(C)(C)OC(=O)NC[C@@H]1C[C@@H](CO)N(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)NC[C@@H]1C[C@@H](C=O)N(C(=O)OC(C)(C)C)C1 -US20070167447A1,3,COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1.OB(O)c1ccc(Cl)cc1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(Cl)cc3)[nH]c2c1 -US20100197908A1,3,C#Cc1ccc(OCc2ccccc2)nn1.OCCc1ccc(I)cc1>>OCCc1ccc(C#Cc2ccc(OCc3ccccc3)nn2)cc1 -US06187966B1,7,O=C(CCl)c1cccc(Cl)c1>>O[C@H](CCl)c1cccc(Cl)c1 -US20150218096A1,3,COC(=O)c1ccc(B(O)O)c(F)c1.O=C(c1c(Cl)cccc1C(F)(F)F)n1nc(Br)c2ncc(CO)cc21>>COC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cc(CO)cnc23)c(F)c1 -US05438052,4,N#Cc1ccc2c(c1)OC(c1ccccc1)(c1ccccc1)O2.[N-]=[N+]=[N-]>>c1ccc(C2(c3ccccc3)Oc3ccc(-c4nnn[nH]4)cc3O2)cc1 -US06214841B1,2,COC(=O)Cl.NCCc1ccccc1>>COC(=O)NCCc1ccccc1 -US07348017B2,2,COc1ccc(S(=O)(=O)Cl)cc1.O=C(O)C1Cc2ccccc2CN1>>COc1ccc(S(=O)(=O)N2Cc3ccccc3CC2C(=O)O)cc1 -US05569768,1,CCCCCCC(Br)C(=O)OCC.N#Cc1ccccc1-c1ccc2[nH]ccc2c1>>CCCCCCC(C(=O)OCC)n1ccc2cc(-c3ccccc3C#N)ccc21 -US20100120762A1,1,COc1ccnc(Cl)c1[N+](=O)[O-].Cc1c[nH]cn1>>COc1ccnc(-n2cnc(C)c2)c1[N+](=O)[O-] -US20130180589A1,3,CCCC[Sn](CCCC)(CCCC)c1cccs1.N#CC(C#N)=Cc1ccc(Br)s1>>N#CC(C#N)=Cc1ccc(-c2cccs2)s1 -US20090209522A1,2,COc1nc(NCCN(C)C(=O)OC(C)(C)C)nc(OC)c1N.Cc1ccc(C(C)(C)C)cc1Oc1nc(C(=O)O)co1>>COc1nc(NCCN(C)C(=O)OC(C)(C)C)nc(OC)c1NC(=O)c1coc(Oc2cc(C(C)(C)C)ccc2C)n1 -US20060142337A1,1,C[C@@H](O[C@H]1CCN(C(=O)[C@@H]2CC[C@@H](NC(=O)CCCCCl)CC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CCN(C(=O)[C@@H]2CC[C@@H](N3CCCCC3=O)CC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20110039852A1,2,CCO.COc1ccc(CC(=O)O)cc1Br>>CCOC(=O)Cc1ccc(OC)c(Br)c1 -US20100152216A1,1,CC1(c2cc(F)cc(F)c2)NC(=O)NC1=O.COc1ccc(CCl)cc1>>COc1ccc(CN2C(=O)NC(C)(c3cc(F)cc(F)c3)C2=O)cc1 -US20060172995A1,1,Fc1ccccc1N1CCNCC1.OCc1cc2ccccc2s1>>Fc1ccccc1N1CCN(Cc2cc3ccccc3s2)CC1 -US06159996,6,COC(=O)CCc1cccc(OC(F)(F)F)c1>>O=C(O)CCc1cccc(OC(F)(F)F)c1 -US04136192,1,BrCCCOc1ccccc1.COC(=O)c1ccc(O)cc1C(=O)OC>>COC(=O)c1ccc(OCCCOc2ccccc2)cc1C(=O)OC -US20120129811A1,2,CCCn1ncc2c(N)cccc21.COc1ccc(S(C)(=O)=O)cc1N=C=S>>CCCn1ncc2c(NC(=S)Nc3cc(S(C)(=O)=O)ccc3OC)cccc21 -US08013156B2,1,CC1CN(C(=O)OC(C)(C)C)CCN1.Clc1nccnc1Cl>>CC1CN(C(=O)OC(C)(C)C)CCN1c1nccnc1Cl -US20150252051A1,6,O=C(OCc1ccccc1)N1C2CCC1C(Cn1ccc3cc(-c4cnn(C5CCCCO5)c4)ccc31)C2>>c1cc2c(ccn2CC2CC3CCC2N3)cc1-c1cnn(C2CCCCO2)c1 -US20150148340A1,1,CCOC(=O)c1cn(-c2ccc3c(c2)ncn3C)c(=O)[nH]c1=O.Cc1c(CBr)cccc1C(F)(F)F>>CCOC(=O)c1cn(-c2ccc3c(c2)ncn3C)c(=O)n(Cc2cccc(C(F)(F)F)c2C)c1=O -US07612094B2,2,NC1CCC(C(=O)O)CC1.O=C(Cl)OCc1ccccc1>>O=C(NC1CCC(C(=O)O)CC1)OCc1ccccc1 -US07906532B2,2,CC(C)n1nc(C(=O)O)c2ccccc21.COC(=O)[C@@H]1C[C@H](N)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@H](NC(=O)c2nn(C(C)C)c3ccccc23)CN1C(=O)OC(C)(C)C -US07498353B2,2,CC(C)C(NC(=O)OC(C)(C)C)C(=O)CCNc1ccnc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1.O=C(Cl)C(Cl)Cl>>CC(C)C(NC(=O)OC(C)(C)C)C(=O)CCN(C(=O)C(Cl)Cl)c1ccnc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1 -US04009184,3,C=O.CC(=O)c1c(-c2ccccc2)oc2c(C)cccc12.CNC>>Cc1cccc2c(C(=O)CCN(C)C)c(-c3ccccc3)oc12 -US20020166994A1,1,CCCc1ccc(-c2ccc(CBr)c(F)c2)c(F)c1.Oc1ccc(F)c(F)c1>>CCCc1ccc(-c2ccc(COc3ccc(F)c(F)c3)c(F)c2)c(F)c1 -US20090264418A1,2,CC1CCNCC1.O=C(O)c1cc2cc(C(=O)N3CCN(C4CCCC4)CC3)ccc2[nH]1>>CC1CCN(C(=O)c2cc3cc(C(=O)N4CCN(C5CCCC5)CC4)ccc3[nH]2)CC1 -US06720324B2,6,CC(=O)Nc1cccc(C2=CCN(C(=O)OC(C)(C)C)CC2)c1>>CC(=O)Nc1cccc(C2=CCNCC2)c1 -US20120149721A1,2,CCC(=O)Cl.CCc1ccc(OCC2CC2)c(-c2ncnc3c(C(=O)N[C@@H]4CNC[C@H]4O)c(C)[nH]c23)c1>>CCC(=O)N1C[C@@H](NC(=O)c2c(C)[nH]c3c(-c4cc(CC)ccc4OCC4CC4)ncnc23)[C@H](O)C1 -US20010051733A1,3,CC(=O)Cl.CCC1CCSc2c(C)ccc(C)c21>>CCC1CCSc2c(C)cc(C(C)=O)c(C)c21 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)C=Cc1cccc(Cl)c1>>CC(C)C[C@H]1CN(C(=O)C=Cc2cccc(Cl)c2)[C@@H](CC(C)C)C(=O)N1 -US07511037B2,1,CCOC(=O)c1nc(C(CCSC)OCCO)[nH]c(=O)c1OCc1ccccc1>>CCOC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CCOC2CCSC -US20100215579A1,1,FCCOCCOCCCl.Oc1ccc2cc(Br)ccc2c1>>FCCOCCOCCOc1ccc2cc(Br)ccc2c1 -US20090197959A1,6,COC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CC(C)(C)C)C(C)=O)c1>>COc1ccc(CC(=O)O)cc1-c1ccc(C(F)(F)F)cc1CN(CC(C)(C)C)C(C)=O -US20050090502A1,2,CCCCCN.COc1ccc(CN2C(=O)CN(c3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc3)S2(=O)=O)cc1>>CCCCCNC(=O)[C@H](Cc1ccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)cc1)NC(=O)OC(C)(C)C -US20100311966A1,1,CC(C)C(=O)CBr.O=C1NC(=O)c2ccccc21>>CC(C)C(=O)CN1C(=O)c2ccccc2C1=O -US20150011508A1,2,Cc1ccc(-c2noc(CCC(C)(C)O)n2)cc1N.Cc1ccn2c(C(=O)O)cnc2c1>>Cc1ccn2c(C(=O)Nc3cc(-c4noc(CCC(C)(C)O)n4)ccc3C)cnc2c1 -US20060189629A1,7,O=[N+]([O-])c1ccc(OCCOc2ccccn2)cc1>>Nc1ccc(OCCOc2ccccn2)cc1 -US20080114061A1,6,COc1cc(OC)cc(C(=CC#N)c2ccc(O[Si](C)(C)C(C)(C)C)c(OC)c2)c1>>COc1cc(OC)cc(C(=CC#N)c2ccc(O)c(OC)c2)c1 -US20090099158A1,6,COC(=O)c1ccc2c(c1)CCN(C(=O)C1CCCCC1)C2>>O=C(O)c1ccc2c(c1)CCN(C(=O)C1CCCCC1)C2 -US20100210636A1,2,NCC1(C(F)(F)F)OC(=O)Nc2ccc(Cl)cc21.O=C(O)c1ccc(F)cc1>>O=C1Nc2ccc(Cl)cc2C(CNC(=O)c2ccc(F)cc2)(C(F)(F)F)O1 -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.CS(=O)(=O)c1ccc(O)cc1F>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4ccc(S(C)(=O)=O)c(F)c4)ncnc32)CC1 -US20150238480A1,3,CCOC(=O)c1c(O)c2cc(I)c(Cl)cc2[nH]c1=O.Cn1ccc2cc(B(O)O)ccc21>>CCOC(=O)c1c(O)c2cc(-c3ccc4c(ccn4C)c3)c(Cl)cc2[nH]c1=O -US20110207731A1,6,COCCN(C)c1n[nH]c2ccc(C3OCCCO3)cc12>>COCCN(C)c1n[nH]c2ccc(C=O)cc12 -US20090281160A1,6,COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CCC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1>>O=C(CCC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O -US20140357858A1,2,CC(C)(C(=O)O)c1ccccc1.Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1>>CC(C)(C(=O)Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1)c1ccccc1 -US20100160379A1,3,CN(C)C=O.Fc1cccc(Oc2ccc(Br)cn2)c1>>O=Cc1ccc(Oc2cccc(F)c2)nc1 -US20150232445A1,1,C[C@H]1CCc2c(ccc(Br)c2O)N1C(=O)C1CC1.OB(O)c1ccccc1>>C[C@H]1CCc2c(ccc(Br)c2Oc2ccccc2)N1C(=O)C1CC1 -US05468742,6,O=C(c1ccccc1)N1C[C@H]2OCCN(Cc3ccccc3)[C@H]2C1>>c1ccc(CN2CCO[C@@H]3CNC[C@@H]32)cc1 -US20080293712A1,1,COc1cc2ncc3c(N)nc(-c4cncc(Br)c4)cc3c2cc1OC.COc1cccc(N)c1>>COc1cccc(Nc2cncc(-c3cc4c(cnc5cc(OC)c(OC)cc54)c(N)n3)c2)c1 -US06548522B1,2,CCCCCCN.COC(=O)C(c1ccc(F)c(F)c1)c1ccccn1>>CCCCCCNC(=O)C(c1ccc(F)c(F)c1)c1ccccn1 -US20070060588A1,3,CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1[N+](=O)[O-].Clc1ccc(O[C@H]2CN3CCC2CC3)nn1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(O[C@H]3CN4CCC3CC4)nn2)cc1[N+](=O)[O-] -US06943183B2,3,Brc1cncc2ccccc12.C=C>>C=Cc1cncc2ccccc12 -US20100240743A1,2,CC(C)(C)CC(=O)Cl.Cc1c(C)c2c(c(C)c1N)C(=O)C(C)(C)O2>>Cc1c(C)c2c(c(C)c1NC(=O)CC(C)(C)C)C(=O)C(C)(C)O2 -US04564612,8,CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CSc2ccccc2N(CC(=O)OC(C)(C)C)C1=O.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CS(=O)c2ccccc2N(CC(=O)OC(C)(C)C)C1=O -US04859233,9,NN.O=C(Cl)c1c(Cl)ccc(Cl)c1Cl>>NNC(=O)c1c(Cl)ccc(Cl)c1Cl -US20030055064A1,1,CC(=O)NC(C)c1ccc(CCl)cc1.Fc1ccc(N2CCNCC2)cc1>>CC(=O)NC(C)c1ccc(CN2CCN(c3ccc(F)cc3)CC2)cc1 -US20110092526A1,1,N[C@H]1CCOC1.O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(Cl)nc1-n1cccn1>>O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(N[C@H]2CCOC2)nc1-n1cccn1 -US20050107377A1,3,Brc1csc2ccccc12.COc1ccc(B(O)O)cc1>>COc1ccc(-c2csc3ccccc23)cc1 -US20130316938A1,3,CC(=O)c1ccc2ccccc2c1.COc1ccc(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>COc1ccc(CC=C(C)c2ccc3ccccc3c2)cc1 -US20150045343A1,3,CNC(=O)CC#N.O=Cc1ccc2cn[nH]c2c1>>CNC(=O)C(C#N)=Cc1ccc2cn[nH]c2c1 -US09040703B2,1,C1CCNC1.CN(C(=O)OC(C)(C)C)C(CCC=O)(CCCCB1OC(C)(C)C(C)(C)O1)C(=O)OC(C)(C)C>>CN(C(=O)OC(C)(C)C)C(CCCCB1OC(C)(C)C(C)(C)O1)(CCCN1CCCC1)C(=O)OC(C)(C)C -US06329392B1,1,CCOCCCl.COc1cc(C(=O)N2CCC(CCN3CCC(C(=O)c4nc5ccccc5[nH]4)CC3)(c3ccccc3)C2)cc(OC)c1OC>>CCOCCn1c(C(=O)C2CCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(OC)c(OC)c(OC)c4)C3)CC2)nc2ccccc21 -US20140228363A1,2,CC(=O)Cl.C[C@H]1CC(c2ccncc2[N+](=O)[O-])=C[C@@H](O[Si](C)(C)C(C)(C)C)[C@@]1(O)CO>>CC(=O)OC[C@@]1(O)[C@@H](C)CC(c2ccncc2[N+](=O)[O-])=C[C@H]1O[Si](C)(C)C(C)(C)C -US20100286191A1,1,CC(C)(C)OC(=O)CBr.CCn1c(C)c[nH]c1=O>>CCn1c(C)cn(CC(=O)OC(C)(C)C)c1=O -US05428038,1,COc1cc2oc(=O)c3c(c2cc1OCCCCl)CCC3.COc1ccc(N2CCNCC2)cc1>>COc1ccc(N2CCN(CCCOc3cc4c5c(c(=O)oc4cc3OC)CCC5)CC2)cc1 -US20100317568A1,6,CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(Br)[nH]1>>Brc1cnc([C@@H]2CCCN2)[nH]1 -US20150099737A1,2,CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)O)cn3)nc2n1C1CCCC1.O[C@@H]1C[C@@H]2C[C@H]1CN2>>CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4C[C@@H]5C[C@H]4C[C@H]5O)cn3)nc2n1C1CCCC1 -US20090118332A1,2,N#Cc1ccc(C2CCNCC2)cc1.Nc1cc(C(=O)O)ccc1OC(F)(F)F>>N#Cc1ccc(C2CCN(C(=O)c3ccc(OC(F)(F)F)c(N)c3)CC2)cc1 -US07432392B2,1,CN(C)C(=O)c1cc(Cl)ccc1[N+](=O)[O-].OCc1ccccc1>>CN(C)C(=O)c1cc(OCc2ccccc2)ccc1[N+](=O)[O-] -US20070249722A1,7,COC(=O)C(NS(=O)(=O)c1ccc(Cl)cc1)C(CC(F)(F)F)CC(F)(F)F>>O=S(=O)(NC(CO)C(CC(F)(F)F)CC(F)(F)F)c1ccc(Cl)cc1 -US20030195173A1,2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=P(OCCO)(OCc1ccccc1)OCc1ccccc1>>O=C(OCCOP(=O)(OCc1ccccc1)OCc1ccccc1)Oc1ccc([N+](=O)[O-])cc1 -US08513252B2,3,COc1ccc(Cn2cc(I)c(C(=O)N(C)OC)n2)cc1.Cc1cccc(Oc2nc(B3OC(C)(C)C(C)(C)O3)cs2)n1>>COc1ccc(Cn2cc(-c3csc(Oc4cccc(C)n4)n3)c(C(=O)N(C)OC)n2)cc1 -US20050031541A1,2,CCCCCCCCO.NCC(=O)CCC(=O)O>>CCCCCCCCOC(=O)CCC(=O)CN -US20150073091A1,2,C=CC(=O)Cl.NCc1ccccc1>>C=CC(=O)NCc1ccccc1 -US20060258691A1,6,CC(C)(C)OC(=O)c1nn(C(C)(C)C)c2nc(F)ccc12>>CC(C)(C)n1nc(C(=O)O)c2ccc(F)nc21 -US20120165310A1,6,CC(C)(C)OC(=O)N1CCC(n2cc(-c3cccc(OCC4CCC(C)(C)O4)c3)c3c(N)ncnc32)CC1>>CC1(C)CCC(COc2cccc(-c3cn(C4CCNCC4)c4ncnc(N)c34)c2)O1 -US05569781,9,COC(=O)C1(C(=O)OC)CC1.N>>COC(=O)C1(C(N)=O)CC1 -US20140213554A1,3,C#Cc1ccccc1.CCOC(=O)c1cnc(N)c(Br)c1>>CCOC(=O)c1cnc(N)c(C#Cc2ccccc2)c1 -US20090312352A1,3,O=C(CN1C(=O)CSC1=S)NCCc1ccccc1.O=Cc1ccc(-c2ccc(C(=O)O)c(O)c2)o1>>O=C(CN1C(=O)C(=Cc2ccc(-c3ccc(C(=O)O)c(O)c3)o2)SC1=S)NCCc1ccccc1 -US08426473B2,3,C#CCN1CCOCC1.CCOC(=O)COc1cc(C)c(Sc2cc(Br)cc(OCC(C)C)c2)cc1C>>CCOC(=O)COc1cc(C)c(Sc2cc(C#CCN3CCOCC3)cc(OCC(C)C)c2)cc1C -US20060069013A1,2,N#Cc1cccc(N)c1.O=C(O)c1ccc2ccccc2c1>>N#Cc1cccc(NC(=O)c2ccc3ccccc3c2)c1 -US20060004017A1,6,COc1cc2c(Oc3ccc(Cl)cc3F)ncnc2cc1C=CC(=O)OC(C)(C)C>>COc1cc2c(Oc3ccc(Cl)cc3F)ncnc2cc1C=CC(=O)O -US06117893,7,O=[N+]([O-])c1cccnc1NCc1ccc(Cl)cc1>>Nc1cccnc1NCc1ccc(Cl)cc1 -US08486967B2,9,CC(C)(C)OC(=O)N1CCC(C)(C(N)=O)CC1>>CC1(N)CCN(C(=O)OC(C)(C)C)CC1 -US03965113,1,Nc1cc(Cl)ccc1[N+](=O)[O-].Sc1ccccc1>>Nc1cc(Sc2ccccc2)ccc1[N+](=O)[O-] -US20050209230A1,1,Fc1cnc(Cl)nc1Cl.Nc1ccc(CO)cc1>>OCc1ccc(Nc2nc(Cl)ncc2F)cc1 -US20140187553A1,2,NNC(=O)Nc1ccccc1.O=C(O)c1ccc2[nH]cc(-c3cncc(C4CC4)n3)c2c1>>O=C(NNC(=O)c1ccc2[nH]cc(-c3cncc(C4CC4)n3)c2c1)Nc1ccccc1 -US05939439,6,CC(C)(C)OC(=O)N1CCc2ncn(Cc3ccc(-n4cc(Cl)ccc4=O)nc3)c2C1c1ccc(C#N)cc1>>N#Cc1ccc(C2NCCc3ncn(Cc4ccc(-n5cc(Cl)ccc5=O)nc4)c32)cc1 -US08822534B2,2,CCCCO.CS(=O)(=O)NC(=O)C[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)CCC(=O)O>>CCCCOC(=O)CCC(=O)N[C@@H](CC(=O)NS(C)(=O)=O)Cc1ccc(-c2cccc(Cl)c2)cc1 -US20140350014A1,2,CCCCN(CCCC)C(=O)c1nn(-c2ccc(OC)cc2C(=O)O)c(C)c1Cl.OC[C@@H]1Cc2ccccc2CN1>>CCCCN(CCCC)C(=O)c1nn(-c2ccc(OC)cc2C(=O)N2Cc3ccccc3C[C@H]2CO)c(C)c1Cl -US20110288067A1,7,C=C(C)c1cnc2[nH]cc(C(=O)N[C@@H](C)C(C)(C)O)c2n1>>CC(C)c1cnc2[nH]cc(C(=O)N[C@@H](C)C(C)(C)O)c2n1 -US20120252807A1,2,NCCc1ccncc1.O=C(O)C1CCN(C(=O)c2cc3ccccc3n2Cc2ccc(Cl)cc2)CC1>>O=C(NCCc1ccncc1)C1CCN(C(=O)c2cc3ccccc3n2Cc2ccc(Cl)cc2)CC1 -US09156827B2,3,COc1ccc2c(c1CCCC1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.O=Cc1n[nH]c2ccccc12>>COc1ccc2c(c1CCCC1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O -US06500832B1,7,CCOC(=O)c1ccc(NC(=O)OC(C)(C)C)nc1>>CC(C)(C)OC(=O)Nc1ccc(CO)cn1 -US07582673B2,2,COc1ccc(C)cc1S(=O)(=O)Cl.Nc1ccccc1NS(=O)(=O)c1cc2ccccc2s1>>COc1ccc(C)cc1S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1cc2ccccc2s1 -US05478851,7,CN(CCOc1ccc(C=C2SC(=O)NC2=O)cc1)C(=O)c1ccccc1>>CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)C(=O)c1ccccc1 -US06136969,6,CC(C)(C)OC(=O)N1CCC[C@@H](OC(=O)c2ccc(OCc3ccccc3)cc2)[C@H](NC(=O)c2ccc(OC(=O)c3ccc(F)cc3)cc2)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](OC(=O)c2ccc(O)cc2)[C@H](NC(=O)c2ccc(OC(=O)c3ccc(F)cc3)cc2)C1 -US20120029023A1,2,COCC(=O)Cl.Nc1ccc(-c2cc(Cc3ccc(OCc4ccccc4)nc3)no2)c(N)n1>>COCC(=O)Nc1ccc(-c2cc(Cc3ccc(OCc4ccccc4)nc3)no2)c(N)n1 -US09150556B2,1,COCC(=O)CC(=O)OC.Nc1ccccc1N>>COCC(CC(=O)OC)Nc1ccccc1N -US20140343035A1,6,COc1cc(C#Cc2nn(C3CCN(C(=O)OC(C)(C)C)C3)c3ncnc(N)c23)cc(OC)c1>>COc1cc(C#Cc2nn(C3CCNC3)c3ncnc(N)c23)cc(OC)c1 -US08883322B2,1,Nc1ccccc1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1Nc1ccccc1 -US20120178736A1,1,CC1(C)CN(C2COC2)CCN1C(=O)c1nc2c(N3CCOCC3)nc(Cl)nc2s1.CCc1nc2ccccc2[nH]1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)N3CCN(C4COC4)CC3(C)C)sc2n1 -US20040044000A1,3,C#CCc1ccccc1.O=c1c2cc(Br)ccc2ccn1Cc1ccc(F)cc1>>O=c1c2cc(C#CCc3ccccc3)ccc2ccn1Cc1ccc(F)cc1 -US04628062,1,CCC(=O)NC1=C(Cl)C(=O)c2ccccc2C1=O.COCCO>>CCC(=O)NC1=C(OCCOC)C(=O)c2ccccc2C1=O -US20150057260A1,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Fc1ccc2c(Cl)nc(Cl)nc2c1>>C=C(OCC)c1nc(Cl)nc2cc(F)ccc12 -US20150203515A1,1,CC(C)[C@@H]1CC[C@H](Oc2ccc3cc(C=O)ccc3c2)CC1.c1ccc(N2CCNCC2)nc1>>CC(C)[C@@H]1CC[C@H](Oc2ccc3cc(CN4CCN(c5ccccn5)CC4)ccc3c2)CC1 -US04016193,6,C#CCOc1ccc(CC(=O)OC)cc1[N+](=O)[O-]>>C#CCOc1ccc(CC(=O)O)cc1[N+](=O)[O-] -US05972978,4,N#CCc1cccc2ccccc12.[N-]=[N+]=[N-]>>c1ccc2c(Cc3nnn[nH]3)cccc2c1 -US20060205718A1,1,CCOC(=O)N1CCC(N)CC1.COC(=O)c1cccc2nc(Cl)oc12>>CCOC(=O)N1CCC(Nc2nc3cccc(C(=O)OC)c3o2)CC1 -US20120316147A1,2,CC(C)(N)C#N.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>CC(C)(C#N)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 -US20090258866A1,3,CC(C)[Si](OC1CCC(OS(=O)(=O)C(F)(F)F)=Cc2cccnc21)(C(C)C)C(C)C.OB(O)c1ccc(F)c(F)c1>>CC(C)[Si](OC1CCC(c2ccc(F)c(F)c2)=Cc2cccnc21)(C(C)C)C(C)C -US06573263B2,7,COc1ccc(Cc2nn3c(C(CCCc4ccccc4)C(C)=O)nc(C)c3c(=O)[nH]2)cc1>>COc1ccc(Cc2nn3c(C(CCCc4ccccc4)C(C)O)nc(C)c3c(=O)[nH]2)cc1 -US20090023762A1,3,CN1C(=O)CC(C)(c2cccc(Br)c2)N=C1N.COc1cc(OS(C)(=O)=O)cc(B2OC(C)(C)C(C)(C)O2)c1>>COc1cc(OS(C)(=O)=O)cc(-c2cccc(C3(C)CC(=O)N(C)C(N)=N3)c2)c1 -US20090042874A1,1,COC(=O)CBr.O=C(OCc1ccccc1)N1CCC(=Cc2ccc(O)c([N+](=O)[O-])c2)CC1>>COC(=O)COc1ccc(C=C2CCN(C(=O)OCc3ccccc3)CC2)cc1[N+](=O)[O-] -US20060100249A1,1,CN(C)CCCl.O=c1c(-c2ccccc2Cl)cc(-c2ccccn2)cn1-c1ccc(O)cc1>>CN(C)CCOc1ccc(-n2cc(-c3ccccn3)cc(-c3ccccc3Cl)c2=O)cc1 -US20090143396A1,1,CC1CNCC(C)N1.O=Cc1ccc(OC(F)(F)F)cc1>>CC1CN(Cc2ccc(OC(F)(F)F)cc2)CC(C)N1 -US20110112140A1,3,Cc1ccc(Br)cc1NC(=O)COCC(=O)Nc1ccc(Cl)cc1C(=O)O.OB(O)c1cccc2cccnc12>>Cc1ccc(-c2cccc3cccnc23)cc1NC(=O)COCC(=O)Nc1ccc(Cl)cc1C(=O)O -US20070232627A1,2,Nc1ccc(Cl)cn1.O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(Nc1ccc(Cl)cn1)c1ccc(Cl)c([N+](=O)[O-])c1 -US05929098,2,C#CC(C)(N)CC.CON=Cc1cc(C(=O)O)cc(Cl)c1N>>C#CC(C)(CC)NC(=O)c1cc(Cl)c(N)c(C=NOC)c1 -US08722730B2,2,CC(C)c1cc(C(=O)O)oc1C(C)C.CCOC(=O)c1cccc(N)c1>>CCOC(=O)c1cccc(NC(=O)c2cc(C(C)C)c(C(C)C)o2)c1 -US20130184257A1,1,CS(=O)(=O)c1cc(F)c(OC2CCN(C3CCNCC3)C2=O)cc1F.N#CBr>>CS(=O)(=O)c1cc(F)c(OC2CCN(C3CCN(C#N)CC3)C2=O)cc1F -US04161480,8,CC(O)/C=C\[Si](C)(C)C>>CC(=O)/C=C/[Si](C)(C)C -US07049444B2,2,CC1(c2cccc(N)c2)C2CN(CCCC3CCCCC3)CC21.CCS(=O)(=O)Cl>>CCS(=O)(=O)Nc1cccc(C2(C)C3CN(CCCC4CCCCC4)CC32)c1 -US20090221548A1,2,COc1ccc(N)cc1OCCN1CCCC1.O=C(O)c1cc(-c2ccc(Cl)cc2)c[nH]1>>COc1ccc(NC(=O)c2cc(-c3ccc(Cl)cc3)c[nH]2)cc1OCCN1CCCC1 -US20130090364A1,3,C#Cc1ccc(Br)cc1.C[C@H]1C[C@@H](c2ncc(I)[nH]2)N(C(=O)OC(C)(C)C)C1>>C[C@H]1C[C@@H](c2ncc(C#Cc3ccc(Br)cc3)[nH]2)N(C(=O)OC(C)(C)C)C1 -US20150111935A1,6,CCOC(=O)/C=C/C=C/CCc1ccccc1>>O=C(O)/C=C/C=C/CCc1ccccc1 -US20130245006A1,3,C#CC(C)(C)NC(C)(C)C.CCc1cc2cc(C(=O)OC(C)C)ccn2c1C(=O)c1ccc(I)cc1>>CCc1cc2cc(C(=O)OC(C)C)ccn2c1C(=O)c1ccc(C#CC(C)(C)NC(C)(C)C)cc1 -US20090023789A1,2,CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)C1(C)CCC(C(=O)O)C1(C)C.CN>>CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)C1(C)CCC(C(=O)NC)C1(C)C -US20090227588A1,6,CC(C)(C)OC(=O)N1CCCC(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)nn2)C1>>O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nn1)C1CCCNC1 -US06936608B2,3,CC1(C)COB(c2ccc(F)c(-n3ccnc3)c2)OC1.FC(F)(F)c1cnn2c(Br)cnc2n1>>Fc1ccc(-c2cnc3nc(C(F)(F)F)cnn23)cc1-n1ccnc1 -US07498460B2,1,BrCCOc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1.COC(=O)c1ccc(O)c(C(=O)N2CCC(C(=O)OC)CC2)c1>>COC(=O)c1ccc(OCCOc2ccc(OCc3ccc(-c4ccccc4)cc3)cc2)c(C(=O)N2CCC(C(=O)OC)CC2)c1 -US20090318493A1,6,CCCC1(C(=O)c2cnc3[nH]ccc3c2)CCCN1C(=O)OC(C)(C)C>>CCCC1(C(=O)c2cnc3[nH]ccc3c2)CCCN1 -US20140315912A1,2,CC(C)(C)OC(=O)N1[C@H](Cc2ccc(C(=O)O)nc2)CC[C@@H]1[C@H](O)c1ccccc1.c1ccc(CN2CCNCC2)nc1>>CC(C)(C)OC(=O)N1[C@H](Cc2ccc(C(=O)N3CCN(Cc4ccccn4)CC3)nc2)CC[C@@H]1[C@H](O)c1ccccc1 -US04551272,2,CC(=O)Oc1ccc(C(=O)O)cc1.CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)N>>CCOC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)c1ccc(OC(C)=O)cc1 -US06469039B1,8,Cn1c(COc2ccc(C#N)cc2)nc2nc(CO)ccc21>>Cn1c(COc2ccc(C#N)cc2)nc2nc(C=O)ccc21 -US07173023B2,1,CI.O=C1Cc2cc(OCc3cccc(F)c3)ccc2C=CN1>>CN1C=Cc2ccc(OCc3cccc(F)c3)cc2CC1=O -US20060116368A1,2,Nc1ccc2c(c1)CN=CN2.O=C(O)C1CCN(c2ccc3ccccc3c2)CC1>>O=C(Nc1ccc2c(c1)CN=CN2)C1CCN(c2ccc3ccccc3c2)CC1 -US08012964B2,6,CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CCCN3CCOCC3)Cc3cccc(CC(=O)OC)c3)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CCCN3CCOCC3)Cc3cccc(CC(=O)O)c3)c2n1 -US06147111,6,CCOC(=O)C(Cc1cc2c(cc1OC)OCO2)C(=O)OCC>>CCOC(=O)C(Cc1cc2c(cc1OC)OCO2)C(=O)O -US04212810,1,Brc1cccnc1.C[Sn](C)(C)Cl>>C[Sn](C)(C)c1cccnc1 -US06680312B2,8,CC(C)(C)OC(=O)N1CCC(CN2CCN(S(=O)(=O)c3ccc(CO)cc3)CC2=O)CC1>>CC(C)(C)OC(=O)N1CCC(CN2CCN(S(=O)(=O)c3ccc(C=O)cc3)CC2=O)CC1 -US20130040930A1,1,CN1CCNC1=O.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2F)CC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CCN(C)C3=O)cc2F)CC1 -US20110034690A1,1,CC1Sc2c(C(=O)O)c(=O)c3cc(F)c(N4CCNCC4)cc3n21.Cc1oc(=O)oc1CBr>>Cc1oc(=O)oc1CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)c2n3C(C)S2)CC1 -US20100137446A1,2,COc1ccc2cccc(C(CN)CO)c2c1.O=C(Cl)CF>>COc1ccc2cccc(C(CO)CNC(=O)CF)c2c1 -US08716483B2,6,COC(=O)C1(OC)CCN(C(=O)OCc2ccccc2)C1>>COC(=O)C1(OC)CCNC1 -US20140187776A1,3,CCOC(=O)Cc1cccc(I)c1.OB(O)c1ccc(C(F)(F)F)cc1Cl>>CCOC(=O)Cc1cccc(-c2ccc(C(F)(F)F)cc2Cl)c1 -US20100029619A1,2,COC(=O)C(C)(C)c1ccc(C(=O)O)cc1.Nc1cn2cc(I)ccc2n1>>COC(=O)C(C)(C)c1ccc(C(=O)Nc2cn3cc(I)ccc3n2)cc1 -US20040063581A1,1,NO.O=C(Cl)Oc1ccccc1>>O=C(NO)Oc1ccccc1 -US20120108583A1,2,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1.Nc1ccc(Br)cc1>>CC1(C)Cc2c(c(C(=O)Nc3ccc(Br)cc3)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1 -US04889857,1,O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O.O=CNCC1CNCCO1>>O=CNCC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CCO1 -US05021433,2,CCN(CC)CC(=O)O.COc1c(C)cnc(CS(=O)c2nc3ccccc3n2CO)c1C>>CCN(CC)CC(=O)OCn1c(S(=O)Cc2ncc(C)c(OC)c2C)nc2ccccc21 -US20070293492A1,7,O=[N+]([O-])c1ccc2nc(N3CCOCC3)ccc2c1>>Nc1ccc2nc(N3CCOCC3)ccc2c1 -US04743602,2,CC(C)(C)c1ccc(C2CC2C(=O)Cl)o1.C[C@H]1CNC[C@@H](C)O1>>C[C@H]1CN(C(=O)C2CC2c2ccc(C(C)(C)C)o2)C[C@@H](C)O1 -US20120202777A1,3,CC(CCc1ccc(Br)cn1)(C(=O)NO)S(C)(=O)=O.OB(O)c1ccccc1>>CC(CCc1ccc(-c2ccccc2)cn1)(C(=O)NO)S(C)(=O)=O -US04797417,7,COC1=C(c2ccccc2)C(CCC(=O)O)OC1=O>>COC1=C(c2ccccc2)C(CCCO)OC1=O -US07618978B2,3,CC(C)(C)OC(=O)N1C[C@H](OCOCc2ccccc2)CC[C@@H]1C=O.O=[N+]([O-])CCc1cc(F)cc(F)c1>>CC(C)(C)OC(=O)N1C[C@H](OCOCc2ccccc2)CC[C@@H]1C(O)C(Cc1cc(F)cc(F)c1)[N+](=O)[O-] -US04147875,6,COC(=O)c1[nH]c(=O)n2c1CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2>>O=C(O)c1[nH]c(=O)n2c1CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2 -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.OB(O)c1cccnc1>>COc1ccc2c(-c3cccnc3)nc(Nc3cc(C)[nH]n3)cc2c1 -US08357689B2,2,O=C([O-])Cc1ccccc1Nc1c(Cl)cccc1Cl>>O=C1Cc2ccccc2N1c1c(Cl)cccc1Cl -US07704994B2,3,CS(=O)(=O)c1ccc(B(O)O)cc1.Clc1cncc(Cl)n1>>CS(=O)(=O)c1ccc(-c2cncc(Cl)n2)cc1 -US05814644,2,Nc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(Cl)CCCl>>O=C(CCCl)Nc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1 -US20090281092A1,1,CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21.Nc1ccc2c(c1)NC(=O)CO2>>CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Nc3ccc4c(c3)NC(=O)CO4)ncc21 -US20060094588A1,8,CC(O)c1nc2ccccc2[nH]1>>CC(=O)c1nc2ccccc2[nH]1 -US20150056141A1,6,CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(Br)ccc12>>CCOC(=O)c1c(N)sc2c(OCCN(CC)CC)c(Br)ccc12 -US04496551,1,C[Si](C)(CCl)c1ccc(Cl)cc1Cl.c1c[nH]cn1>>C[Si](C)(Cn1ccnc1)c1ccc(Cl)cc1Cl -US20110124875A1,1,C[S-].N#Cc1cc(F)cc(Br)c1>>CSc1cc(F)cc(C#N)c1 -US20090131483A1,7,CCOC(=O)/C=C/c1cc(C(=O)NCc2ccc(S(=O)(=O)C3CC3)cc2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C>>CCOC(=O)CCc1cc(C(=O)NCc2ccc(S(=O)(=O)C3CC3)cc2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C -US08053581B2,2,COc1ccc(-c2nc(N)sc2Cc2ccccc2)cc1.COc1ccc(CCC(=O)Cl)cc1OC>>COc1ccc(-c2nc(NC(=O)CCc3ccc(OC)c(OC)c3)sc2Cc2ccccc2)cc1 -US20140134133A1,3,C#CC(C)O.COc1ncc(-c2ccc3ncc(I)n3c2)cc1NS(=O)(=O)c1ccc(F)cc1F>>COc1ncc(-c2ccc3ncc(C#CC(C)O)n3c2)cc1NS(=O)(=O)c1ccc(F)cc1F -US20110166147A1,3,CC1(C)OB(c2ccc(O)cc2)OC1(C)C.NS(=O)(=O)c1ccc(CNc2nccn3c(Br)cnc23)cc1>>NS(=O)(=O)c1ccc(CNc2nccn3c(-c4ccc(O)cc4)cnc23)cc1 -US20130317065A1,9,COC(=O)c1cccc(C(O)c2c(-c3csc(C)c3)[nH]c3cc(OC)ccc23)n1>>COC(=O)c1cccc(Cc2c(-c3csc(C)c3)[nH]c3cc(OC)ccc23)n1 -US20030105092A1,6,CCOC(=O)c1cc(CCCO[Si](C)(C)C(C)(C)C)[nH]n1>>CCOC(=O)c1cc(CCCO)[nH]n1 -US05883255,2,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.CCC(O)c1cc2n(c(=O)c1C)Cc1cc3ccccc3nc1-2>>CCC(OC(=O)C(NC(=O)OC(C)(C)C)C(C)C)c1cc2n(c(=O)c1C)Cc1cc3ccccc3nc1-2 -US07049444B2,7,CCCCCCN1CC2C(C1=O)C2(C)c1cccc(O)c1>>CCCCCCN1CC2C(C1)C2(C)c1cccc(O)c1 -US05587392,1,CNc1cc(F)ccc1[N+](=O)[O-].Oc1ccc(C(F)(F)F)cc1Cn1cncn1>>CNc1cc(Oc2ccc(C(F)(F)F)cc2Cn2cncn2)ccc1[N+](=O)[O-] -US20100048543A1,3,Brc1cnc(NCCN2CCOCC2)nc1.C#Cc1cncc(N)c1>>Nc1cncc(C#Cc2cnc(NCCN3CCOCC3)nc2)c1 -US05091384,1,CCI.O=C(O)c1cn(C2CC2)c2c(F)c(N3CC4=C(CNC4)C3)c(F)cc2c1=O>>CCN1CC2=C(C1)CN(c1c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c1F)C2 -US20080146566A1,1,CN(C)CCCl.Cc1ccc(C(=O)NC2CC2)cc1-n1ccc2ccc(O)cc2c1=O>>Cc1ccc(C(=O)NC2CC2)cc1-n1ccc2ccc(OCCN(C)C)cc2c1=O -US07902252B2,6,CCOC(=O)c1cc2c([nH]1)C(c1ccc(C)cc1)CC2>>Cc1ccc(C2CCc3cc(C(=O)O)[nH]c32)cc1 -US08673942B2,1,CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(O)c2[nH]1.OCC1CCOCC1>>CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(OCC3CCOCC3)c2[nH]1 -US06525042B1,8,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CO)CC1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C=O)CC1 -US20060194968A1,2,Cc1nc2c3c(c(C(=O)O)cc2n1C)CCC(c1ccccc1)O3.NCC(O)CO>>Cc1nc2c3c(c(C(=O)NCC(O)CO)cc2n1C)CCC(c1ccccc1)O3 -US20150158831A1,2,CC(=O)OC(C)=O.CN1CCNCC1>>CC(=O)N1CCN(C)CC1 -US06432950B1,1,Cc1sc2nc(-c3ccno3)nc(Cl)c2c1Cl.NCCc1ccccc1>>Cc1sc2nc(-c3ccno3)nc(NCCc3ccccc3)c2c1Cl -US20050215589A1,2,CS(=O)(=O)Cl.OCCc1c(-c2ccccc2)[nH]c2ccccc12>>CS(=O)(=O)OCCc1c(-c2ccccc2)[nH]c2ccccc12 -US08592454B2,2,CC(=O)N1CCC(C(=O)O)CC1.CN(C(=O)N(C)[C@@H]1CCNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)N(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](c3ccc(F)cc3)C2)CC1 -US20110124626A1,1,CC=O.O=C(OCC1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)CCNCC2>>CCN1CCc2ccc(C(=O)OCC3CCN(Cc4ccccc4)CC3)cc2CC1 -US05336778,7,CCCCc1nnc(SCC(=O)OC)n1Cc1ccc([N+](=O)[O-])cc1>>CCCCc1nnc(SCC(=O)OC)n1Cc1ccc(N)cc1 -US04048223,3,CCBr.O=c1c2ccccc2ccc2ccccc12>>CCC1(O)c2ccccc2C=Cc2ccccc21 -US20130035331A1,1,C1CCNC1.ClCc1cccc(I)c1>>Ic1cccc(CN2CCCC2)c1 -US20150246934A1,6,Cn1ccc(OCc2ccccc2)cc1=O>>Cn1ccc(O)cc1=O -US20110237791A1,7,COc1nc(C#C[C@H]2CCC(=O)N2)ccc1Cl>>COc1nc(/C=C\[C@H]2CCC(=O)N2)ccc1Cl -US20140135330A1,7,CC[C@@H]([C@@H](O)c1ccc(OC)cc1)[N+](=O)[O-]>>CC[C@H](N)[C@@H](O)c1ccc(OC)cc1 -US08415378B2,6,COC(=O)N1CCC(CO[Si](C)(C)C(C)(C)C)CC1CC(C)(C)c1ccccc1>>COC(=O)N1CCC(CO)CC1CC(C)(C)c1ccccc1 -US04374773,2,CNC.Cc1nnc2n1-c1ccc(N=C=O)cc1C(c1ccccc1Cl)=NC2>>Cc1nnc2n1-c1ccc(NC(=O)N(C)C)cc1C(c1ccccc1Cl)=NC2 -US20070287725A1,7,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)c(C)c(NCc3cc(-c4ccc(F)cc4)no3)c2[N+](=O)[O-])cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)c(C)c(NCc3cc(-c4ccc(F)cc4)no3)c2N)cc1 -US20020052322A1,2,CC[C@H](N)C(=O)OC.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>CC[C@H](NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1)C(=O)OC -US20150080412A1,2,CCNC(=O)N(N)Cc1ccc(C(C)(C)C)cc1.O=C(O)COCc1ccc(Br)cc1>>CCNC(=O)N(Cc1ccc(C(C)(C)C)cc1)NC(=O)COCc1ccc(Br)cc1 -US20130244267A1,3,C#Cc1ccccc1.COC(=O)c1ccc(I)cc1>>COC(=O)c1ccc(C#Cc2ccccc2)cc1 -US20150152096A1,1,CCOC(=O)C1=C(CBr)NC(c2nccs2)=NC1c1ccc(F)cc1Br.NC(=O)CCC1CNCCO1>>CCOC(=O)C1=C(CN2CCOC(CCC(N)=O)C2)NC(c2nccs2)=NC1c1ccc(F)cc1Br -US20070293521A1,1,NCc1ccc2c(c1)OCCO2.Oc1cccc(Nc2nc(Cl)ncc2F)c1>>Oc1cccc(Nc2nc(NCc3ccc4c(c3)OCCO4)ncc2F)c1 -US20140088117A1,7,Cn1ncc(NC(=O)c2nc(C3=CCCC3)sc2N)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1>>Cn1ncc(NC(=O)c2nc(C3CCCC3)sc2N)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1 -US20130267493A1,6,COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCCN4CCOCC4)cc3)cc12>>O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCCN4CCOCC4)cc3)cc12 -US20060135554A1,3,CCOc1ccc(Cc2nc3cc(C=O)ccc3n2CC2CC2)cc1.C[Mg+]>>CCOc1ccc(Cc2nc3cc(C(C)O)ccc3n2CC2CC2)cc1 -US08933105B2,2,CCn1cc(S(=O)(=O)Cl)cn1.CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C>>CCn1cc(S(=O)(=O)n2cc(CN(C)C(=O)OC(C)(C)C)c(F)c2-c2cccnc2F)cn1 -US06509341B1,6,CCCCN(CCCC)C(=O)COCc1ccccc1>>CCCCN(CCCC)C(=O)CO -US20080312226A1,2,O=C(Nc1cn2nc(Cl)ccc2n1)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1cn2nc(Cl)ccc2n1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 -US07417169B2,2,CS(=O)(=O)Cl.C[C@H](CO)NC(=O)OC(C)(C)C>>C[C@H](COS(C)(=O)=O)NC(=O)OC(C)(C)C -US20120252801A1,2,CC(C)c1ccc(N)cc1.CC1(C)CN(c2ccccc2)C(CC(=O)O)C(=O)O1>>CC(C)c1ccc(NC(=O)CC2C(=O)OC(C)(C)CN2c2ccccc2)cc1 -US20040176361A1,1,CN1CCNCC1.Cc1cccc2cc(Cl)[nH]c(=O)c12>>Cc1cccc2cc(N3CCN(C)CC3)[nH]c(=O)c12 -US05811439,7,COC(=O)c1cccc2c1ccn2Cc1nc(-c2ccccc2)oc1C>>Cc1oc(-c2ccccc2)nc1Cn1ccc2c(CO)cccc21 -US20100305104A1,1,CC1CCC(C)N1.O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>CC1CCC(C)N1c1ccc(C(=O)O)cc1[N+](=O)[O-] -US08367681B2,3,CN1CCN(c2ccc(Nc3ccn4ncc(C=O)c4n3)cc2)CC1.O=C1CNC(=O)N1>>CN1CCN(c2ccc(Nc3ccn4ncc(C=C5NC(=O)NC5=O)c4n3)cc2)CC1 -US20100120770A1,2,Cc1ccnc(Nc2ncc(Sc3ccnc(C(=O)O)c3F)s2)c1.NCC1(c2ccccc2)CCOCC1>>Cc1ccnc(Nc2ncc(Sc3ccnc(C(=O)NCC4(c5ccccc5)CCOCC4)c3F)s2)c1 -US05459138,7,O=[N+]([O-])c1ccc(Cl)nc1Cl>>Nc1ccc(Cl)nc1Cl -US08329729B2,2,Cc1cncc(N)n1.O=C(Br)CBr>>Cc1cncc(NC(=O)CBr)n1 -US06432993B1,1,CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-].Oc1ccc(-n2ccnc2)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-n3ccnc3)cc2)ccc1[N+](=O)[O-] -US20080076924A1,2,Cc1ccccc1NC(=NC#N)N1CCNC(c2ccccc2)C1.O=S(=O)(Cl)c1ccc(Cl)cc1>>Cc1ccccc1NC(=NC#N)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)C(c2ccccc2)C1 -US06479490B2,1,COC(=O)Cc1cccc(O)c1.OCCCl>>COC(=O)Cc1cccc(OCCCl)c1 -US20070049582A1,1,COc1cc2nc[nH]c(=O)c2cc1OC.OCCBr>>COc1cc2ncn(CCO)c(=O)c2cc1OC -US20110098429A1,3,CC(=O)c1cccc(B(O)O)c1.O=S(=O)(Oc1cccc(-c2ccccc2)c1OCc1ccccc1)C(F)(F)F>>CC(=O)c1cccc(-c2cccc(-c3ccccc3)c2OCc2ccccc2)c1 -US07138425B2,1,CCCN.Cc1ccc2nc(-c3cc([N+](=O)[O-])ccc3F)oc2c1>>CCCNc1ccc([N+](=O)[O-])cc1-c1nc2ccc(C)cc2o1 -US08748434B2,1,COC(=O)c1cc(Cl)cc(I)c1.CS(=O)[O-]>>COC(=O)c1cc(Cl)cc(S(C)(=O)=O)c1 -US03944409,2,CNCC=O.O=C=Nc1nnc(C2CCCCCC2)s1>>CN(CC=O)C(=O)Nc1nnc(C2CCCCCC2)s1 -US20070049593A1,3,COC(=O)c1ccc2c(C3CCCCC3)c(B3OC(C)(C)C(C)(C)O3)[nH]c2c1.O=[N+]([O-])c1cccc(Br)c1OCCOC1CCCCO1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cccc([N+](=O)[O-])c3OCCOC3CCCCO3)[nH]c2c1 -US04410536,4,CN1CCC(=O)CC1.Cc1csc2ccc(NN)cc12>>Cc1csc2ccc3[nH]c4c(c3c12)CN(C)CC4 -US06936607B2,1,CNC.CSc1nc(Cl)cc(Cl)n1>>CSc1nc(Cl)cc(N(C)C)n1 -US20070293521A1,1,CC(N)c1ccc(O)cc1.Fc1cnc(Cl)nc1Cl>>CC(Nc1nc(Cl)ncc1F)c1ccc(O)cc1 -US20090221555A1,1,C#CCNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl.CC(C)OC(=O)N1CCCOc2cc(N)ccc21>>C#CCNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)OCCCN3C(=O)OC(C)C)ncc1Cl -US06063782,1,CC1CC1CBr.Cc1cc(C(=O)CCc2ccc(F)cc2F)[nH]c1C>>Cc1cc(C(=O)CCc2ccc(F)cc2F)n(CC2CC2C)c1C -US20100240610A1,6,Cn1c(=O)c(C(=O)NCC(=O)OC(C)(C)C)c(O)c2ccc(-c3cccc(C#N)c3)cc21>>Cn1c(=O)c(C(=O)NCC(=O)O)c(O)c2ccc(-c3cccc(C#N)c3)cc21 -US20040235917A1,2,CNc1nc(C)c(S(N)(=O)=O)s1.O=C(O)Cc1ccc(-c2ccccn2)cc1>>Cc1nc(N(C)C(=O)Cc2ccc(-c3ccccn3)cc2)sc1S(N)(=O)=O -US06228867B1,4,CC[Si](C#C[C@H](C)COCc1ccccc1)(CC)CC.COC(=O)C(C)(C)c1cnc(N)c(I)c1>>CC[Si](CC)(CC)c1[nH]c2ncc(C(C)(C)C(=O)OC)cc2c1[C@H](C)COCc1ccccc1 -US08778937B2,4,BrCCOCCBr.Cc1c(Cn2c(C(C)C)nc3c(Br)cc(N)cc32)cccc1C(F)(F)F>>Cc1c(Cn2c(C(C)C)nc3c(Br)cc(N4CCOCC4)cc32)cccc1C(F)(F)F -US20070014727A1,1,C=C(C)C.O=C(O)CCCOCc1ccccc1>>CC(C)(C)OC(=O)CCCOCc1ccccc1 -US20070249670A1,6,COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)OC(C)(C)C)C1CCCCC1>>COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1N)C1CCCCC1 -US20100056516A1,2,CCOC(=O)c1c(O)c2cccnc2n(OCc2ccccc2)c1=O.NCc1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)c1c(O)c2cccnc2n(OCc2ccccc2)c1=O -US04694014,1,FC(F)Cl.Sc1nnc(-c2ccc(Cl)cc2)s1>>FC(F)Sc1nnc(-c2ccc(Cl)cc2)s1 -US20020193367A1,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2cccn2)c1.CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3cccn3)c2)cc1C(F)(F)F -US06762321B2,2,COc1cc(CCN)ccc1OCc1ccccc1.Cc1ccc(CC(=O)Cl)cc1>>COc1cc(CCNC(=O)Cc2ccc(C)cc2)ccc1OCc1ccccc1 -US20050181988A1,7,CC(=O)CCCCC(=O)O>>CC(O)CCCCC(=O)O -US20150183802A1,2,CC(C)COc1ncc(N2CCOc3cc4c(N)noc4cc32)cc1Cl.CS(=O)(=O)Cl>>CC(C)COc1ncc(N2CCOc3cc4c(NS(C)(=O)=O)noc4cc32)cc1Cl -US07332510B2,1,COc1ccnc(Cl)n1.Cc1nc(C#Cc2ccnc(Cl)c2)c[nH]1>>COc1ccnc(-n2cc(C#Cc3ccnc(Cl)c3)nc2C)n1 -US20040087626A1,3,Cc1ccc([N+](=O)[O-])cc1Br.OB(O)c1ccncc1Cl>>Cc1ccc([N+](=O)[O-])cc1-c1ccncc1Cl -US08003662B2,1,CN1CCNCC1.Nc1ccc(Oc2ccnc3cc(I)sc23)c(F)c1>>CN1CCN(c2cc3nccc(Oc4ccc(N)cc4F)c3s2)CC1 -US05101059,7,O=C(O)C1c2ccccc2Oc2ccccc21>>OCC1c2ccccc2Oc2ccccc21 -US20070249670A1,6,COC(=O)C(NC(=O)c1cc2ccccc2cc1NC(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C(F)(F)F)CC1>>COC(=O)C(NC(=O)c1cc2ccccc2cc1N)[C@@H]1CC[C@@H](C(F)(F)F)CC1 -US20120059028A1,3,CC1(C)OB(c2ccc3ncsc3c2)OC1(C)C.COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1Cl)CCCC3>>COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc2ncsc2c1)CCCC3 -US08841291B2,2,C=C(CO)c1ccccc1.CS(=O)(=O)Cl>>C=C(COS(C)(=O)=O)c1ccccc1 -US07011838B2,7,N#CC(C#N)=Cc1ccc(OC(F)(F)F)cc1>>N#CC(C#N)Cc1ccc(OC(F)(F)F)cc1 -US20150038490A1,6,O=C(OCc1ccccc1)N1CC[C@@H](c2ccccc2)C[C@H]1C1CCCC(F)(F)C1>>FC1(F)CCCC([C@@H]2C[C@H](c3ccccc3)CCN2)C1 -US20050240034A1,9,BrC(Br)(Br)Br.CN(C)c1ccc(CCO)cc1>>CN(C)c1ccc(CCBr)cc1 -US07547690B2,1,CI.c1ccc(CN2C3CCNCC2CC3)cc1>>CN1CCC2CCC(C1)N2Cc1ccccc1 -US20110245257A1,6,CC(NC(=O)OCc1ccccc1)c1nc2cnccn2c1-c1ccccn1>>CC(N)c1nc2cnccn2c1-c1ccccn1 -US20100004222A1,7,O=[N+]([O-])c1cnc2[nH]c(CO)nc2c1>>Nc1cnc2[nH]c(CO)nc2c1 -US09079880B2,2,COC(=O)c1cccc(OCC(=O)O)c1.N#Cc1ccc(N)cc1>>COC(=O)c1cccc(OCC(=O)Nc2ccc(C#N)cc2)c1 -US20060100249A1,3,C#Cc1ccccc1.O=c1c(Br)cc(-c2ccccn2)cn1-c1ccccc1>>O=c1c(C#Cc2ccccc2)cc(-c2ccccn2)cn1-c1ccccc1 -US06326386B1,2,CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)O)c1)c1ccncc1.N#CCCNc1ccccc1F>>CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)N(CCC#N)c2ccccc2F)c1)c1ccncc1 -US04116969,2,O=C=Nc1ncc(Br)s1.O=CCNCCl>>O=CCN(CCl)C(=O)Nc1ncc(Br)s1 -US20100087427A1,1,CC(C)I.OCc1cccc(O)c1>>CC(C)Oc1cccc(CO)c1 -US20140051708A1,1,CCc1cccc(CC)c1NC(=O)c1cc(-c2ccnc(Nc3ccc(Br)cc3OC)n2)n(C)n1.CN1CCNCC1>>CCc1cccc(CC)c1NC(=O)c1cc(-c2ccnc(Nc3ccc(N4CCN(C)CC4)cc3OC)n2)n(C)n1 -US20080188520A1,4,NC(c1ccccn1)C(O)c1ccccc1.O=C(Cl)CCCCl>>O=C1CCCN1C(c1ccccn1)C(O)c1ccccc1 -US20150094319A1,6,CC(C)(C)OC(=O)N1CC[C@@H](n2nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1c(-c1ccc(C(=O)Nc3cc(C(F)(F)F)ccn3)cc1)nn2[C@@H]1CCNC1 -US20130210804A1,6,COC(=O)C1CCC2C=Cc3ccccc3C(=O)N2C1>>O=C(O)[C@@H]1CC[C@H]2C=Cc3ccccc3C(=O)N2C1 -US20150175530A1,3,C#C[C@@H](O)CCO.COC(=O)[C@@H](NC(=O)c1ccc(C#CBr)cc1)C(C)(C)N>>COC(=O)[C@@H](NC(=O)c1ccc(C#CC#C[C@@H](O)CCO)cc1)C(C)(C)N -US08481568B2,2,NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccccn1>>O=C1CCC(N2Cc3c(CNC(=O)c4ccccn4)cccc3C2=O)C(=O)N1 -US20100210680A1,7,C[C@]12CN(Cc3ccccc3)C(=O)[C@H]1c1ccc(Br)c(Cl)c1CO2>>C[C@]12CN(Cc3ccccc3)C[C@H]1c1ccc(Br)c(Cl)c1CO2 -US08445684B2,6,CO[C@@H](Cc1ccccc1)Cc1cccc(-c2cncc(OC[C@H]3CCN3C(=O)OC(C)(C)C)c2)c1>>CO[C@H](Cc1ccccc1)Cc1cccc(-c2cncc(OC[C@@H]3CCN3)c2)c1 -US07943651B2,2,COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cc(C)cc2c1cnn2-c1cccc(C(=O)O)c1)C(F)(F)F.C[C@@H](N)C(N)=O>>COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cc(C)cc2c1cnn2-c1cccc(C(=O)N[C@H](C)C(N)=O)c1)C(F)(F)F -US07037918B2,1,NCCNc1ccc(-c2ncc[nH]2)c(-c2ccc(Cl)cc2Cl)n1.Nc1nc(Cl)ccc1[N+](=O)[O-]>>Nc1nc(NCCNc2ccc(-c3ncc[nH]3)c(-c3ccc(Cl)cc3Cl)n2)ccc1[N+](=O)[O-] -US06201121B1,1,NCC(=O)O.O=C(O)c1ccc(Cl)cc1Cl>>O=C(O)CNc1cc(Cl)ccc1C(=O)O -US20100009969A1,6,C[C@@H]1CCCN1CCCOc1ccc(-c2nc3c(s2)CN(C(=O)OC(C)(C)C)CC3)cc1>>C[C@@H]1CCCN1CCCOc1ccc(-c2nc3c(s2)CNCC3)cc1 -US08604015B2,1,CN1CCC(C(=O)OC(c2cccc(F)c2)c2cccc(F)c2)CC1.O=C(CCl)c1cccs1>>C[N+]1(CC(=O)c2cccs2)CCC(C(=O)OC(c2cccc(F)c2)c2cccc(F)c2)CC1 -US20080021043A1,6,CCCC(C(=O)OC)[C@@H]1CCCN(Cc2cc(C(F)(F)F)ccc2C(F)(F)F)[C@H]1c1ccc(C(F)(F)F)cc1>>CCCC(C(=O)O)[C@@H]1CCCN(Cc2cc(C(F)(F)F)ccc2C(F)(F)F)[C@H]1c1ccc(C(F)(F)F)cc1 -US04540692,2,COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C.Nc1cccccc1=O>>CN1C(C(=O)Nc2cccccc2=O)=C(O)c2ccccc2S1(=O)=O -US05506227,8,Cc1cccnc1C.O=C(OO)c1cccc(Cl)c1>>Cc1ccc[n+]([O-])c1C -US05856314,9,BrC(Br)(Br)Br.CCOP(=O)(OCC)C(Nc1ccc(CCCO)cn1)P(=O)(OCC)OCC>>CCOP(=O)(OCC)C(Nc1ccc(CCCBr)cn1)P(=O)(OCC)OCC -US07572915B2,1,O=[N+]([O-])c1ccc(F)cc1.SC1CCCC1>>O=[N+]([O-])c1ccc(SC2CCCC2)cc1 -US20040087552A1,8,O=C(OCc1ccccc1)C1(CN2C[C@H](CO)[C@@H](c3cccc(F)c3)C2)CCCCC1>>O=C[C@H]1CN(CC2(C(=O)OCc3ccccc3)CCCCC2)C[C@@H]1c1cccc(F)c1 -US04279908,1,COC(=O)Cl.Cc1c(Cl)cc(-c2ccc(=O)[nH]n2)cc1Cl>>COC(=O)n1nc(-c2cc(Cl)c(C)c(Cl)c2)ccc1=O -US20080119466A1,2,CC(C)(C)C(=O)OC(=O)C(C)(C)C.Nc1ccc2c(ccn2-c2ccc(NC(=O)N(O)c3ccc(Cl)c(C(F)(F)F)c3)cc2)c1>>CC(C)(C)C(=O)Nc1ccc2c(ccn2-c2ccc(NC(=O)N(O)c3ccc(Cl)c(C(F)(F)F)c3)cc2)c1 -US04525589,2,C1CNCCN1.O=S(=O)(Cl)c1cccc2cnccc12>>O=S(=O)(c1cccc2cnccc12)N1CCNCC1 -US20060205759A1,6,CCOC(=O)C1CCc2sc3ccccc3c2C1>>O=C(O)C1CCc2sc3ccccc3c2C1 -US20140371199A1,3,Brc1ccn2nccc2n1.CCOC(=O)c1ccc(B(O)O)cc1>>CCOC(=O)c1ccc(-c2ccn3nccc3n2)cc1 -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N(C)C)c1=O.C[C@@H](N)CO>>C[C@H](CO)NC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N(C)C)c1=O -US06262045B1,2,CNC.Cn1c2ccccc2c2c(CC(=O)O)nn(-c3ccccc3)c(=O)c21>>CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccccc1n2C -US20120189548A1,1,CCN(CC)C(=O)Cc1c(-c2ccc(O)cc2)nn2c(C)cc(C)nc12.Cc1ccc(S(=O)(=O)OCCO)cc1>>CCN(CC)C(=O)Cc1c(-c2ccc(OCCOS(=O)(=O)c3ccc(C)cc3)cc2)nn2c(C)cc(C)nc12 -US20110166146A1,1,CNC.O=c1nc(Cl)ccn1Cc1c(-c2ccc(Cl)cc2)nc2ccccn12>>CN(C)c1ccn(Cc2c(-c3ccc(Cl)cc3)nc3ccccn23)c(=O)n1 -US04143061,2,CC(C)(N=C=O)c1ccc(Cl)c(Cl)c1.CCNC1CCCCC1>>CCN(C(=O)NC(C)(C)c1ccc(Cl)c(Cl)c1)C1CCCCC1 -US20100113502A1,1,C=CCBr.O=[N+]([O-])c1ccc2c(c1)C1CN(C3CCOCC3)CCC1N2>>C=CCN1c2ccc([N+](=O)[O-])cc2C2CN(C3CCOCC3)CCC21 -US08486967B2,1,Cc1cc(N2CCC(N)CC2)ncn1.Clc1ccc(-c2cc(C3CC3)cn3nc(Br)nc23)cc1>>Cc1cc(N2CCC(Nc3nc4c(-c5ccc(Cl)cc5)cc(C5CC5)cn4n3)CC2)ncn1 -US20110224204A1,1,C1=COCCC1.Oc1ccccc1I>>Ic1ccccc1OC1CCCCO1 -US20060074064A1,8,OCc1cn2c(n1)sc1cc(Cl)ccc12>>O=Cc1cn2c(n1)sc1cc(Cl)ccc12 -US06498251B1,1,CC(C)(C)OC(=O)N1CCc2c([nH]c3ccccc23)C1.COC(=O)CBr>>COC(=O)Cn1c2c(c3ccccc31)CCN(C(=O)OC(C)(C)C)C2 -US20090143354A1,1,N#CC1CCNCC1.O=C(NCC1CCCCC1)c1c(Cl)ccc2nc(Cl)ccc12>>N#CC1CCN(c2ccc3c(C(=O)NCC4CCCCC4)c(Cl)ccc3n2)CC1 -US20120157436A1,6,CC(C)(C)OC(=O)N1CCn2c(nnc2-c2ncns2)C1>>c1nsc(-c2nnc3n2CCNC3)n1 -US06548533B2,7,CCOC(=O)C1CN(Cc2ccccc2)CC1c1ccc([N+](=O)[O-])cc1>>CCOC(=O)C1CN(Cc2ccccc2)CC1c1ccc(N)cc1 -US20140121231A1,6,Cc1cccc2c(=O)[nH]c3c(c12)COC(C(C)(C)OCc1ccccc1)C3>>Cc1cccc2c(=O)[nH]c3c(c12)COC(C(C)(C)O)C3 -US20140073809A1,6,COc1cccc([C@H](C)[N+](C)(C)[C@@H](C)c2ccccc2)c1>>C[C@@H](c1ccccc1)[N+](C)(C)[C@@H](C)c1cccc(O)c1 -US20120283434A1,1,CC(C)(C)N.CS(=O)(=O)OC[C@H]1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1>>CC(C)(C)NC[C@H]1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1 -US20130210804A1,9,NC(=O)C1CCC2CSc3ccccc3C(=O)N2C1>>N#CC1CCC2CSc3ccccc3C(=O)N2C1 -US20140088094A1,7,O=C1COc2ccc(Br)cc2N1>>Brc1ccc2c(c1)NCCO2 -US20050090491A1,2,CN(C)CCCN.Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)O)cc3)c2)o1>>Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCCCN(C)C)cc3)c2)o1 -US04168269,1,CCCI.O=C1Nc2ccccc2Nc2cscc21>>CCCN1C(=O)c2cscc2Nc2ccccc21 -US06608087B1,6,Cc1nc(-c2ccccc2)oc1-c1cc(CNC(=O)OC(C)(C)C)[nH]n1>>Cc1nc(-c2ccccc2)oc1-c1cc(CN)[nH]n1 -US04808715,2,NCCCl.O=S(=O)(Cl)c1ccc(Nc2cnnc3cc(Cl)ccc23)cc1>>O=S(=O)(NCCCl)c1ccc(Nc2cnnc3cc(Cl)ccc23)cc1 -US06150352,7,Cc1cc(C)cc(-c2c(OCCC3CCCCN3C(=O)OC(C)(C)C)c3cc(C=Nc4ccncn4)c(Cl)cc3[nH]c2=O)c1>>Cc1cc(C)cc(-c2c(OCCC3CCCCN3C(=O)OC(C)(C)C)c3cc(CNc4ccncn4)c(Cl)cc3[nH]c2=O)c1 -US20110207770A1,2,NN.O=C(O)[C@](O)(c1ccccc1)C1CCCCC1>>NNC(=O)[C@](O)(c1ccccc1)C1CCCCC1 -US20100093723A1,2,CS(=O)(=O)Cl.N#Cc1cccc(-c2nc(N)c3cc(CCO)sc3n2)c1>>CS(=O)(=O)OCCc1cc2c(N)nc(-c3cccc(C#N)c3)nc2s1 -US07642267B2,4,CCNc1ccc(C#N)cc1N.O=C(O)Cc1ccnn1-c1cccc(F)c1>>CCn1c(Cc2ccnn2-c2cccc(F)c2)nc2cc(C#N)ccc21 -US20040063735A1,2,C1CCN(C2CCNCC2)CC1.COC(=O)C(Cc1cnc(OC)nc1)NC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1>>COc1ncc(CC(NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCCCC3)CC2)cn1 -US20120316147A1,2,CN(C)C(=O)[C@@H](N)CC1CC1.O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1>>CN(C)C(=O)[C@H](CC1CC1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 -US20050203082A1,2,CS(=O)(=O)Cl.Cc1noc(=O)n1CC=CCCO>>Cc1noc(=O)n1CC=CCCOS(C)(=O)=O -US20070191457A1,7,COc1ccc([N+](=O)[O-])cc1OCC(=O)N1CCC(C)CC1>>COc1ccc([N+](=O)[O-])cc1OCCN1CCC(C)CC1 -US20090227555A2,6,COC(=O)C1(C)CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(C)CCNCC1 -US20030187041A1,2,CC(C)(C)OC(=O)C(C)(C)Sc1ccc(CCN(CC(=O)O)Cc2ccco2)cc1.COc1cc(C)c(N)cc1C>>COc1cc(C)c(NC(=O)CN(CCc2ccc(SC(C)(C)C(=O)OC(C)(C)C)cc2)Cc2ccco2)cc1C -US20150232481A1,2,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(CO)nn23)CC1.CS(=O)(=O)Cl>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(COS(C)(=O)=O)nn23)CC1 -US04125614,7,O=[N+]([O-])c1cc(Br)ccc1Cl>>Nc1cc(Br)ccc1Cl -US05843992,6,CCOC(=O)[C@H]1O[C@@H]1C(=O)NC(c1ccccc1)c1ccccc1>>O=C(NC(c1ccccc1)c1ccccc1)[C@H]1O[C@@H]1C(=O)O -US20040122057A1,1,CCOC(=O)Cl.CCOC(C(=O)NCc1ccc(C(=N)N)cc1)c1c(F)cc(-c2ccc(N)nc2)cc1F>>CCOC(=O)N=C(N)c1ccc(CNC(=O)C(OCC)c2c(F)cc(-c3ccc(N)nc3)cc2F)cc1 -US20090186886A1,1,C1COCCN1.O=CCCc1nc2cc3c(cc2[n+]([O-])n1)CCO3>>[O-][n+]1nc(CCCN2CCOCC2)nc2cc3c(cc21)CCO3 -US07179918B2,6,COC(=O)[C@H]1N(C(=O)OC(C)(C)C)CC(F)(F)C1(C)C>>CC(C)(C)OC(=O)N1CC(F)(F)C(C)(C)[C@H]1C(=O)O -US20080255152A1,1,NC(=O)c1ccc(Oc2ccc(C=O)cc2Cl)cn1.NCCc1cccnc1>>NC(=O)c1ccc(Oc2ccc(CNCCc3cccnc3)cc2Cl)cn1 -US20090221555A1,1,CNC(=O)c1cccc(F)c1Nc1nc(Cl)ncc1Cl.COCCN1CCc2ccc(N)cc2CC1>>CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)CCN(CCOC)CC3)ncc1Cl -US06727264B1,2,CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](N)c3ccccc3)CC2)c1.O=C(Cl)c1cccs1>>CC(C)C(=O)Nc1cccc(C2CCN(CC[C@H](NC(=O)c3cccs3)c3ccccc3)CC2)c1 -US20120021074A1,9,CCOC(=O)c1c[nH]nc1N.ICI>>CCOC(=O)c1c[nH]nc1I -US20110306606A1,1,Nc1cccc(N)c1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>Nc1cccc(Nc2nc(Cl)ccc2[N+](=O)[O-])c1 -US20100305092A1,1,COCCN.O=Cc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1>>COCCNCc1ccc(-c2noc(-c3nnn(-c4ccccc4F)c3-c3ccncc3)n2)cc1 -US20080027112A1,1,COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1O.O=[N+]([O-])c1ccc(CBr)cc1>>COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCc1ccc([N+](=O)[O-])cc1 -US20070010511A1,1,CC(=O)NCCc1cccc2cc(CCl)oc12.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2cc3cccc(CCNC(C)=O)c3o2)cc1 -US20120214840A1,1,CCC(O)(c1nnc(N)o1)C(F)(F)F.CCOC(=O)c1cn2cc(C=O)ccc2c1-c1ccc(F)cc1>>CCOC(=O)c1cn2cc(CNc3nnc(C(O)(CC)C(F)(F)F)o3)ccc2c1-c1ccc(F)cc1 -US07569704B1,3,CCCCCCn1c2ccc(Br)cc2c2cc(Br)ccc21.CCCC[Sn](CCCC)(CCCC)c1cccn1C>>CCCCCCn1c2ccc(Br)cc2c2cc(-c3cccn3C)ccc21 -US20030149266A1,1,Clc1ncc(Br)c(Nc2ccccc2)n1.Nc1ccc(CC(=O)O)cc1>>O=C(O)Cc1ccc(Nc2ncc(Br)c(Nc3ccccc3)n2)cc1 -US20090042896A1,6,C[C@H](Oc1ccc(C#N)cn1)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(F)c(Cl)c1>>C[C@H](Oc1ccc(C#N)cn1)[C@H]1CNC[C@@H]1c1ccc(F)c(Cl)c1 -US07919502B2,3,CCOC(=O)c1ccc(B(O)O)cc1.FC(F)(F)c1ccc(Cl)cc1CN1CCNc2ncc(I)cc21>>CCOC(=O)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1 -US08084611B2,1,CC[C@@H](N)CC(=O)O.FC(F)(F)c1ccc(Br)cc1>>CC[C@H](CC(=O)O)Nc1ccc(C(F)(F)F)cc1 -US04003909,2,COC(=O)Cl.Nc1ccc(-c2noc(-c3ccccn3)n2)cc1>>COC(=O)Nc1ccc(-c2noc(-c3ccccn3)n2)cc1 -US20060264424A1,1,CC(C)CN(c1cccc(C(O)(C#CC=O)C(F)(F)F)c1)S(=O)(=O)c1ccccc1.CC(C)N>>CC(C)CN(c1cccc(C(O)(C#CCNC(C)C)C(F)(F)F)c1)S(=O)(=O)c1ccccc1 -US07638648B2,3,CC(=O)Cl.CCC1(CC)CC(C)(C)c2cc(Br)ccc2O1>>CCC1(CC)CC(C)(C)c2cc(Br)cc(C(C)=O)c2O1 -US06015822,1,CC1(C)CC(=O)c2ccccc21.[NH4+]>>CC1(C)CC(N)c2ccccc21 -US20050070574A1,6,COC(=O)c1c(CN2CCC(N3CCCCC3=O)CC2)c(-c2ccccc2)nc2ccccc12>>O=C(O)c1c(CN2CCC(N3CCCCC3=O)CC2)c(-c2ccccc2)nc2ccccc12 -US20090054508A1,4,Nc1ccccc1/C=C/c1n[nH]c2ccccc12.O=C1OC(=O)C2=C1CCCC2>>O=C1C2=C(CCCC2)C(=O)N1c1ccccc1/C=C/c1n[nH]c2ccccc12 -US20150126490A1,3,CN1CC(c2cnc(N)c(Br)c2)CCC1=O.O=C(N[C@H](CO)c1cccc(Cl)c1)c1ccc(B(O)O)cc1F>>CN1CC(c2cnc(N)c(-c3ccc(C(=O)N[C@H](CO)c4cccc(Cl)c4)c(F)c3)c2)CCC1=O -US03997572,9,CS(=O)(=O)Cl.O>>CS(=O)(=O)O -US20150175562A1,9,COC(=O)c1sc(Br)c(Br)c1Cl>>COC(=O)c1scc(Br)c1Cl -US20020161006A1,6,CCOC(=O)CCc1ccccc1COCCN1CCCC1>>O=C(O)CCc1ccccc1COCCN1CCCC1 -US20090198063A1,1,COc1ccc2ncc(=O)n(CCN3CCC(N)CC3)c2n1.O=Cc1ccc2c(n1)NC(=O)CS2>>COc1ccc2ncc(=O)n(CCN3CCC(NCc4ccc5c(n4)NC(=O)CS5)CC3)c2n1 -US05356926,6,COC(=O)c1ccc(NC(=O)c2sc3ccc(OC)cc3c2OC(C)C)cc1>>COc1ccc2sc(C(=O)Nc3ccc(C(=O)O)cc3)c(OC(C)C)c2c1 -US20150164974A1,6,COC(=O)c1ccc(CO[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)OC(C)(C)C)C2)cc1>>COC(=O)c1ccc(CO[C@@H]2CN[C@H](C(=O)N[C@@H]3CCCc4ccccc43)C2)cc1 -US20110060146A1,7,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(C#CC2(O)CCCC2)c(C)c1>>CCC(CC)(c1ccc(O)c(C)c1)c1ccc(/C=C/C2(O)CCCC2)c(C)c1 -US05288819,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC(F)(F)C(F)F>>Cc1ccc(S(=O)(=O)OCC(F)(F)C(F)F)cc1 -US20070219214A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C(O)[C@@H]1CCCCN1>>CC(C)(C)OC(=O)N1CCC(N2CCCCC2C(=O)O)CC1 -US06632816B1,2,CC(C)CN([C@H](CO)CCCNC(=O)[C@@H](N)Cc1cccc2ccccc12)S(=O)(=O)c1ccc(N)cc1.COC(=O)C(=O)Cl>>COC(=O)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)NCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 -US20130116234A1,1,CCOC(=O)c1c(OS(=O)(=O)C(F)(F)F)nc2ccc(Cl)cc2c1Cc1ccccc1Cl.CNC>>CCOC(=O)c1c(N(C)C)nc2ccc(Cl)cc2c1Cc1ccccc1Cl -US20150252038A1,2,COC(=O)c1cc(C2CC2)c(OCC2CCNCC2)cc1F.Nc1ccc(F)cc1C(=O)O>>COC(=O)c1cc(C2CC2)c(OCC2CCN(C(=O)c3cc(F)ccc3N)CC2)cc1F -US20090216014A1,1,FC(F)(F)c1ccc2c(SCc3ccccc3CBr)ccnc2c1.O=c1cc(CN2CCOCC2)occ1O>>O=c1cc(CN2CCOCC2)occ1OCc1ccccc1CSc1ccnc2cc(C(F)(F)F)ccc12 -US06114325,2,CCCCCCCCCCCCCCCCCCN(C)C(=O)c1ccccc1CO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCCCCCCCCCCCCCCCCN(C)C(=O)c1ccccc1COS(=O)(=O)c1ccc(C)cc1 -US05298652,2,CCCCCCCCCCCCCCCCCCOc1cc(C(=O)O)cc([N+](=O)[O-])c1.COC(=O)CNCC(=O)OC>>CCCCCCCCCCCCCCCCCCOc1cc(C(=O)N(CC(=O)OC)CC(=O)OC)cc([N+](=O)[O-])c1 -US07968554B2,7,Cc1ccc(NC(=O)c2cccc(Cl)c2)cc1OC(=O)c1cccc(Cl)c1>>Cc1ccc(NC(=O)c2cccc(Cl)c2)cc1O -US20100056491A1,4,Nc1c[nH]c2cccnc12.ON=C(CCl)CCCl>>O/N=C1/CCN(c2c[nH]c3cccnc23)C1 -US20110275797A1,1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(I)cc1OCc1ccccc1.CNCCN(C)C>>CN(C)CCN(C)c1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2C(=O)OC(C)(C)C)c(OCc2ccccc2)c1 -US05206229,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCC1(O)CCCCC1>>Cc1ccc(S(=O)(=O)OCCC2(O)CCCCC2)cc1 -US20120035131A1,6,COC(=O)c1ccc2c(c1)OCC1C2=NN(c2ccc(C#N)c(C)c2)C1C1=CCCC1>>Cc1cc(N2N=C3c4ccc(C(=O)O)cc4OCC3C2C2=CCCC2)ccc1C#N -US20120264750A1,2,Nc1cc(C(F)(F)F)ccc1O.O=C(O)c1ccncc1I>>O=C(Nc1cc(C(F)(F)F)ccc1O)c1ccncc1I -US04404138,1,COc1cc2oc(=O)c3c(c2cc1OC)CCNC3.ClCCN1CC2CCCC(C2)C1>>COc1cc2oc(=O)c3c(c2cc1OC)CCN(CCN1CC2CCCC(C2)C1)C3 -US08501750B2,1,COc1ccc(C(=O)CBr)cc1.N#Cc1ccccc1-c1cc(F)c(Cn2c(=O)[nH]c(=O)c3cc(CC(F)(F)F)sc32)c(F)c1>>COc1ccc(C(=O)Cn2c(=O)c3cc(CC(F)(F)F)sc3n(Cc3c(F)cc(-c4ccccc4C#N)cc3F)c2=O)cc1 -US20070191416A1,6,CCOC(=O)Cn1c2c(c3ccccc31)CN(C(=O)OC(C)(C)C)CC2>>CC(C)(C)OC(=O)N1CCc2c(c3ccccc3n2CC(=O)O)C1 -US06048864,7,COc1cc([N+](=O)[O-])c(C#N)cc1OCc1ccccc1>>COc1cc(N)c(C#N)cc1OCc1ccccc1 -US20120208819A1,1,C[C@H](NC(=O)c1cc(C(F)(F)F)cnc1Cl)c1ccc(F)cc1.NCc1ccc(-c2cnc3[nH]ncc3c2)cc1>>C[C@H](NC(=O)c1cc(C(F)(F)F)cnc1NCc1ccc(-c2cnc3[nH]ncc3c2)cc1)c1ccc(F)cc1 -US20120295874A1,2,CC1(C)OC2CNCC2O1.N#Cc1ccc(C(=O)NCc2ccc(OCC(=O)O)cc2)cc1>>CC1(C)OC2CN(C(=O)COc3ccc(CNC(=O)c4ccc(C#N)cc4)cc3)CC2O1 -US07091214B2,7,CC(C)Cn1cnc2c(N)nc3ccc(C=Cc4ccncc4)cc3c21>>CC(C)Cn1cnc2c(N)nc3ccc(CCc4ccncc4)cc3c21 -US20110207947A1,4,CCCCCCC/C=C/C=C(\CC(=O)OC)C(=O)OC.O=C(OO)c1cccc(Cl)c1>>CCCCCCCC1OC1/C=C(\CC(=O)OC)C(=O)OC -US07128900B2,6,COc1ccc(-c2cc(=O)c3ccc(O)cc3o2)cc1>>O=c1cc(-c2ccc(O)cc2)oc2cc(O)ccc12 -US04604389,1,COc1cc2c(cc1OC)N(Cc1ccccc1)C(=O)N(CCCCl)CC2.NCCNc1cc(Cl)c(N)c(Cl)c1>>COc1cc2c(cc1OC)N(Cc1ccccc1)C(=O)N(CCCNCCNc1cc(Cl)c(N)c(Cl)c1)CC2 -US20060241302A1,1,Clc1ncccn1.NCCCNc1cc(C(c2cc(F)ccc2F)S(=O)(=O)c2ccc(Cl)cc2)c(Cl)cn1>>O=S(=O)(c1ccc(Cl)cc1)C(c1cc(F)ccc1F)c1cc(NCCCNc2ncccn2)ncc1Cl -US20140200206A1,2,COc1cc(C(=O)N[C@H](C)CO)ccc1[N+](=O)[O-].CS(=O)(=O)Cl>>COc1cc(C(=O)N[C@H](C)COS(C)(=O)=O)ccc1[N+](=O)[O-] -US07781443B2,1,C1CCNC1.CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(Br)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(N3CCCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC -US05585394,2,CCOc1ccc2[nH]c(=O)n(C3CCCC3)c2c1.COC(=O)c1ccc(S(=O)(=O)Cl)c(OC)c1>>CCOc1ccc2c(c1)n(C1CCCC1)c(=O)n2S(=O)(=O)c1ccc(C(=O)OC)cc1OC -US20150166485A1,3,FC(F)(F)c1nc2cc(Cl)c(I)cc2[nH]1.OB(O)c1ccc(Cl)cc1Cl>>FC(F)(F)c1nc2cc(Cl)c(-c3ccc(Cl)cc3Cl)cc2[nH]1 -US20150051171A1,1,Cc1cccc(-n2nnn(C)c2=O)c1CBr.Oc1ccn(-c2cccc(F)c2)n1>>Cc1cccc(-n2nnn(C)c2=O)c1COc1ccn(-c2cccc(F)c2)n1 -US08431525B2,6,COc1ccc(-c2cnc(NC(=O)Cc3ccccc3)c(Cc3ccccc3)n2)cc1>>O=C(Cc1ccccc1)Nc1ncc(-c2ccc(O)cc2)nc1Cc1ccccc1 -US20060069013A1,7,O=C1NC(=O)C(=Cc2ccccn2)S1>>O=C1NC(=O)C(Cc2ccccn2)S1 -US20090270433A1,7,O=C(O)c1cc([N+](=O)[O-])ccc1Br>>O=[N+]([O-])c1ccc(Br)c(CO)c1 -US05686482,1,CC(C)I.COC(=O)c1ccc(O)cc1O>>COC(=O)c1ccc(OC(C)C)cc1O -US20140051679A1,3,CC1(C)OB(c2ccc(OC3CCN(C4COC4)CC3)cc2)OC1(C)C.O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccsc1)N1CCCC1>>O=C(Nc1ccc2[nH]nc(-c3ccc(OC4CCN(C5COC5)CC4)cc3)c2c1)C(c1ccsc1)N1CCCC1 -US04029809,2,N#CCO.O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1>>N#CCOS(=O)(=O)c1cccc([N+](=O)[O-])c1 -US06248740B1,1,CCOC(=O)CCNC(=O)c1cn2nc(Cl)ccc2n1.NCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>CCOC(=O)CCNC(=O)c1cn2nc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)ccc2n1 -US20060205790A1,3,CC1(C)OCc2cc([C@@H]3CN(CCc4ccc5c(c4)O[C@H](COCc4cncc(Br)c4)CO5)C(=O)O3)ccc2O1.CS(=O)c1ccc(B(O)O)cc1>>CS(=O)c1ccc(-c2cncc(COC[C@@H]3COc4ccc(CCN5C[C@@H](c6ccc7c(c6)COC(C)(C)O7)OC5=O)cc4O3)c2)cc1 -US20100249054A9,3,CC(C)(C)OC(=O)NCc1ccc(Br)cc1.CC1(C)OB(c2ccoc2)OC1(C)C>>CC(C)(C)OC(=O)NCc1ccc(-c2ccoc2)cc1 -US07094902B2,2,CCCCCCCCC1(CCCCCCCC)c2ccccc2-c2ccc(C(=O)Cl)cc21.NNC(=O)c1cc(Cl)ccc1Cl>>CCCCCCCCC1(CCCCCCCC)c2ccccc2-c2ccc(C(=O)NNC(=O)c3cc(Cl)ccc3Cl)cc21 -US20140249126A1,8,CCn1nc(CO)c(=O)c2c(Cl)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21>>CCn1nc(C=O)c(=O)c2c(Cl)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21 -US20050014767A1,6,CC(C)(C)[Si](C)(C)Oc1ccc(-c2ccc(C=O)cn2)cc1C12CC3CC(CC(C3)C1)C2>>O=Cc1ccc(-c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)nc1 -US20110230462A1,3,C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12)C(=O)N1CC(C#N)C1.O=C(O)c1cccc(B(O)O)c1>>C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cccc(C(=O)O)c3)nc12)C(=O)N1CC(C#N)C1 -US08003649B2,9,Fc1ccc(C(F)F)c(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)c1>>Fc1ccc(C(F)F)c(CN2CCN(c3ccc4nnc(C(F)F)n4n3)CC2)c1 -US06172084B2,1,C=[N+]=[N-].O=C(O)c1cc(-c2c[nH]c3ccccc23)nc2ccccc12>>COC(=O)c1cc(-c2c[nH]c3ccccc23)nc2ccccc12 -US07186715B2,2,CC(C)(C)OC(=O)N1CCN(c2ccccc2OC2CCCNC2)CC1.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2ccccc2OC2CCCN(C(=O)c3ccccc3)C2)CC1 -US20120101086A1,1,CC(C)Oc1ccc(-c2nnc(-n3cc4c(n3)CCNC4)s2)cc1C#N.CCOC(=O)CCCBr>>CCOC(=O)CCCN1CCc2nn(-c3nnc(-c4ccc(OC(C)C)c(C#N)c4)s3)cc2C1 -US20120316193A1,1,C1CCNCC1.O=C(CCl)c1cnn(-c2ccc(Cl)cc2)c1>>O=C(CN1CCCCC1)c1cnn(-c2ccc(Cl)cc2)c1 -US20100022594A1,7,CCC(CC)[C@H](NS(=O)(=O)c1ccc(Cl)s1)C(=O)O>>CCC(CC)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)s1 -US07354933B2,1,CC1(C)NC(=O)N(c2ccc(OC(F)(F)F)cc2)C1=O.Clc1cc(CBr)ccn1>>CC1(C)C(=O)N(c2ccc(OC(F)(F)F)cc2)C(=O)N1Cc1ccnc(Cl)c1 -US20060122065A1,2,COc1ccc(CCC(=O)Cl)cc1OC.NCc1ccc(Cl)cc1>>COc1ccc(CCC(=O)NCc2ccc(Cl)cc2)cc1OC -US06303659B2,2,NCC12CC3CC(CC(C3)C1)C2.O=C(O)c1cc(F)ccc1Br>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(F)ccc1Br -US08293768B2,2,Cc1nc(N2CCN(Cc3ccc(C(F)F)o3)C2=O)sc1C(=O)O.NCc1cccnc1>>Cc1nc(N2CCN(Cc3ccc(C(F)F)o3)C2=O)sc1C(=O)NCc1cccnc1 -US07550461B2,6,COC(=O)c1cc2cccc([N+](=O)[O-])c2s1>>O=C(O)c1cc2cccc([N+](=O)[O-])c2s1 -US04518597,1,BrCCCCSc1ccccc1.CC1(C)OC(=O)Nc2ccc(O)cc21>>CC1(C)OC(=O)Nc2ccc(OCCCCSc3ccccc3)cc21 -US20100137313A1,1,COc1nc(Cl)ncc1Br.Nc1cccc(F)c1>>COc1nc(Nc2cccc(F)c2)ncc1Br -US05153214,2,Cc1ccc(S(=O)(=O)Cl)cc1.OC(CCCCOC1CCCCO1)CCCc1cccnc1>>Cc1ccc(S(=O)(=O)OC(CCCCOC2CCCCO2)CCCc2cccnc2)cc1 -US04960758,1,CN(C)C(=S)Cl.N#Cc1ccc(C(=O)c2cc(C(F)(F)F)ccc2O)cc1>>CN(C)C(=S)Oc1ccc(C(F)(F)F)cc1C(=O)c1ccc(C#N)cc1 -US20050245543A1,3,CC(c1ccc(-c2ccc(Br)c(F)c2)cc1)N1CCCC1.COc1ncc(B(O)O)cn1>>COc1ncc(-c2ccc(-c3ccc(C(C)N4CCCC4)cc3)cc2F)cn1 -US06517836B1,9,NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Cl>>NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 -US04661481,2,NCCCN1CCN(Cc2ccc(Cl)cc2)CC1.S=C=NC1CCCCC1>>S=C(NCCCN1CCN(Cc2ccc(Cl)cc2)CC1)NC1CCCCC1 -US04168315,7,COC(=O)Cc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)s1>>COc1ccc(-c2nc(CCO)sc2-c2ccc(OC)cc2)cc1 -US20070197510A1,7,COC(=O)C(C#N)=CC(C)(C)C>>COC(=O)C(C#N)CC(C)(C)C -US20030199578A1,2,Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12.O=C(Cl)c1cccs1>>O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)c1cccs1 -US20080039459A1,1,Cc1nc2ccccc2[nH]1.Clc1nc(N2CCOCC2)c2sccc2n1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2sccc2n1 -US20020019523A1,2,O=C(Cl)OCc1ccccc1.O=C(O)C1(C2CCCCC2)CCNCC1>>O=C(OCc1ccccc1)N1CCC(C(=O)O)(C2CCCCC2)CC1 -US05019577,1,CC(=O)Nc1nc(N(C(C)=O)C(C)=O)c(CCC=O)c(=O)[nH]1.CCOC(=O)CC[C@H](NC(=O)c1ccc(N)c(C)c1)C(=O)OCC>>CCOC(=O)CC[C@H](NC(=O)c1ccc(NCCCc2c(N(C(C)=O)C(C)=O)nc(NC(C)=O)[nH]c2=O)c(C)c1)C(=O)OCC -US20100125081A1,1,CC(C)(C)S(N)=O.Cc1cnc(C#N)c(C(=O)c2cccc(Br)c2)c1>>Cc1cnc(C#N)c(C(=NS(=O)C(C)(C)C)c2cccc(Br)c2)c1 -US05719135,2,O=C(Cl)CO.O=C1Nc2ncccc2C1=Cc1ccc(O)cc1>>O=C(CO)Oc1ccc(C=C2C(=O)Nc3ncccc32)cc1 -US20110092459A1,6,CCOC(OCC)[C@H](C)N(Cc1cccc2cccnc12)C(=O)[C@H](C)NC(=O)OCC1c2ccccc2-c2ccccc21>>CCOC(OCC)[C@H](C)N(Cc1cccc2cccnc12)C(=O)[C@H](C)N -US04720572,1,CCC(=O)O.CCOC(=O)CC(=O)CCl>>CCOC(=O)CC(=O)COC(=O)CC -US04259337,2,FC(F)(F)c1cccc(C2CCCNC2)c1.O=CO>>O=CN1CCCC(c2cccc(C(F)(F)F)c2)C1 -US20100029609A1,2,CC(C)(C)OC[C@H](N)C(=O)OC(C)(C)C.O=C(Nc1cccc(-c2ccc(C(=O)O)cc2)c1)OCC1c2ccccc2-c2ccccc21>>CC(C)(C)OC[C@H](NC(=O)c1ccc(-c2cccc(NC(=O)OCC3c4ccccc4-c4ccccc43)c2)cc1)C(=O)OC(C)(C)C -US07662862B2,2,CCNCCCN1CCc2cccc3c2C1CC3.Cc1ccc(S(=O)(=O)Cl)cc1>>CCN(CCCN1CCc2cccc3c2C1CC3)S(=O)(=O)c1ccc(C)cc1 -US07348017B2,6,COC(=O)Cc1ccc(OCC=C(C)CCC=C(C)C)cc1>>CC(C)=CCCC(C)=CCOc1ccc(CC(=O)O)cc1 -US20070082907A1,6,CCOC(=O)c1cc2cccc(Br)c2[nH]1>>O=C(O)c1cc2cccc(Br)c2[nH]1 -US08129376B2,1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=C1C2CC3CC(C2)CC1C3>>CC(C)(C)OC(=O)N1CCC(NC2C3CC4CC(C3)CC2C4)CC1 -US20040180887A1,2,Cn1cc(-c2ccc(F)cc2)c(C(=O)O)n1.c1ccc2sc(CC3CCCCN3)cc2c1>>Cn1cc(-c2ccc(F)cc2)c(C(=O)N2CCCCC2Cc2cc3ccccc3s2)n1 -US20070208053A1,6,CC(=O)n1ccc2c(I)ccnc21>>Ic1ccnc2[nH]ccc12 -US20060111378A1,1,C[C@@H](O)[C@@H](C)Oc1nc(Cl)ncc1Br.Cc1cc(N)cc(C)c1S(N)(=O)=O>>Cc1cc(Nc2ncc(Br)c(O[C@H](C)[C@@H](C)O)n2)cc(C)c1S(N)(=O)=O -US20120028919A1,2,COC(=O)c1cc2ccccc2n1N.O=C(N=C=S)c1ccccc1>>COC(=O)c1cc2ccccc2n1NC(=S)NC(=O)c1ccccc1 -US20140242028A1,1,O=[N+]([O-])c1ccc(F)c(Cl)c1.Oc1ccccc1>>O=[N+]([O-])c1ccc(Oc2ccccc2)c(Cl)c1 -US07560558B2,1,COc1ccc(Oc2ccnc3cc(O)c(OC)cc23)c(C(C)=O)c1.ClCCCBr>>COc1ccc(Oc2ccnc3cc(OCCCCl)c(OC)cc23)c(C(C)=O)c1 -US20110065743A1,7,CCOC(=O)C1CCc2cc(OC)ccc2C1=O>>CCOC(=O)C1CCc2cc(OC)ccc2C1 -US07179812B2,3,C#CCCn1ccnn1.FC(F)(F)c1ccc(C=Cc2nc(COc3ncc(Br)cn3)co2)cc1>>FC(F)(F)c1ccc(C=Cc2nc(COc3ncc(C#CCCn4ccnn4)cn3)co2)cc1 -US20150210681A1,6,CCOC(=O)C1(c2ccc(-c3ccc(COCc4cccnc4)cc3)cc2)CC1>>O=C(O)C1(c2ccc(-c3ccc(COCc4cccnc4)cc3)cc2)CC1 -US06420409B1,3,C#Cc1ccccc1.CCOC(=O)c1ccc2nc(C)n(Cc3ccc(I)cc3Cl)c2c1>>CCOC(=O)c1ccc2nc(C)n(Cc3ccc(C#Cc4ccccc4)cc3Cl)c2c1 -US08946225B2,1,Cc1ccc(F)cc1O.Cn1nccc(NCC(=O)N2CCC(O)CC2)c1=O>>Cc1ccc(F)cc1OC1CCN(C(=O)CNc2ccnn(C)c2=O)CC1 -US20060223797A1,1,C#CCCCOS(C)(=O)=O.c1cnc(N2CCNCC2)nc1>>C#CCCCN1CCN(c2ncccn2)CC1 -US20100041892A1,1,CCOC(=O)CCc1cc(OC(C)C)n[nH]1.Fc1ccc(CBr)c(F)c1>>CCOC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(F)cc1F -US20120101039A1,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(I)cc1>>COC(=O)C=Cc1ccc(I)cc1 -US07960374B2,7,CC(C)C1=NCCOc2ccc3c(ccn3S(=O)(=O)c3ccccc3)c21>>CC(C)C1NCCOc2ccc3c(ccn3S(=O)(=O)c3ccccc3)c21 -US20090198063A1,3,COC(=O)c1cncc(Cl)n1.OB(O)c1ccco1>>COC(=O)c1cncc(-c2ccco2)n1 -US05674886,1,Cn1nnc2ccc(CCl)cc21.O=[N+]([O-])c1ccc(Nn2cnnc2)cc1>>Cn1nnc2ccc(CN(c3ccc([N+](=O)[O-])cc3)n3cnnc3)cc21 -US20090227591A1,2,CCO.O=C(O)c1cc(F)cc([N+](=O)[O-])c1>>CCOC(=O)c1cc(F)cc([N+](=O)[O-])c1 -US05444082,1,N[C@@H](CCl)C(=O)O.SC1CCC2(CC1)CCC(CCc1ccoc1)CC2>>NC(CSC1CCC2(CCC(CCc3ccoc3)CC2)CC1)C(=O)O -US08598226B2,7,COc1ccc2c(CC(=O)O)coc2c1>>COc1ccc2c(c1)OCC2CC(=O)O -US20050197350A1,6,CCOC(=O)c1cccnc1Oc1ccc(F)cc1>>O=C(O)c1cccnc1Oc1ccc(F)cc1 -US06632826B1,2,CC(C)(C)N.CC(C)(C)OC(=O)N1C(Cc2ccccc2)C(CC2CCC(=O)CC2C(=O)O)OC1(C)C>>CC(C)(C)NC(=O)C1CC(=O)CCC1CC1OC(C)(C)N(C(=O)OC(C)(C)C)C1Cc1ccccc1 -US20060241100A1,3,CCOC(=O)c1nn(-c2ccccc2Cl)c(Br)c1C=O.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(C(F)(F)F)cc2)c1C=O -US20060100429A1,3,C#CC(C)(C)O.Clc1nc(I)nc2[nH]cnc12>>CC(C)(O)C#Cc1nc(Cl)c2nc[nH]c2n1 -US06211362B1,2,CCOC(=O)CCNC.O=C(O)c1cc[nH]c1>>CCOC(=O)CCN(C)C(=O)c1cc[nH]c1 -US08426437B2,2,Nc1ccc2[nH]c(=O)c3[nH]ccc3c2c1.O=C(Cl)c1ccccc1>>O=C(Nc1ccc2[nH]c(=O)c3[nH]ccc3c2c1)c1ccccc1 -US09126948B2,1,CC(=O)c1cc(Cl)c(F)c(Br)c1O.CI>>COc1c(C(C)=O)cc(Cl)c(F)c1Br -US20060100201A1,7,CN1CCN(c2ccc([N+](=O)[O-])c(N3CCC(F)CC3)c2)CC1>>CN1CCN(c2ccc(N)c(N3CCC(F)CC3)c2)CC1 -US20110034462A1,1,CCN(CC)C(=O)CBr.O=C(O)CCS>>CCN(CC)C(=O)CSCCC(=O)O -US20040110804A1,2,CC1(C)OC(=O)C(=CC(=O)Cl)O1.NCc1ccc(F)c(F)c1>>CC1(C)OC(=O)C(=CC(=O)NCc2ccc(F)c(F)c2)O1 -US20060270848A1,1,CCI.Cc1[nH]cnc1C=O>>CCn1cnc(C=O)c1C -US08530461B2,1,CC(=O)NC(C)(C)c1ccc(Br)cc1.c1cc(OC2CNC2)ccc1OCC1CC1>>CC(=O)NC(C)(C)c1ccc(N2CC(Oc3ccc(OCC4CC4)cc3)C2)cc1 -US20100112090A1,1,COCOCCBr.O=Cc1c(O)ccc(F)c1F>>COCOCCOc1ccc(F)c(F)c1C=O -US06169086A,1,COc1ccc(CO)cc1.Fc1cc(F)cc(Br)c1>>COc1ccc(COc2cc(F)cc(Br)c2)cc1 -US20130040930A1,1,Cc1cnc(N2CCN(C(=O)c3ccc(Cl)nn3)CC2)c(C)c1.O=C1CCCN1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCC4=O)nn3)CC2)c(C)c1 -US20090275590A1,1,Cn1c2c(c3ccc(Br)cc31)CN(C(=O)OC(C)(C)C)CC2.O=c1cc(OCc2ccccc2)cn[nH]1>>Cn1c2c(c3ccc(-n4ncc(OCc5ccccc5)cc4=O)cc31)CN(C(=O)OC(C)(C)C)CC2 -US05112829,2,COC(=O)CSC1CCCc2nc3ccccc3c(N)c21>>O=C1CSC2CCCc3nc4ccccc4c(c32)N1 -US20150126511A1,7,CN(C)C(=O)C1(c2ccccc2)CCCCC1>>CN(C)CC1(c2ccccc2)CCCCC1 -US07960419B2,4,COc1ccc(C(N)=C(C)C(N)=S)cc1>>COc1ccc(-c2nsc(N)c2C)cc1 -US03960868,6,CCOC(=O)c1cnc2cc(C3CCCCC3)ccc2c1O>>O=C(O)c1cnc2cc(C3CCCCC3)ccc2c1O -US20120083482A1,1,CCn1cc(-c2cc3nccc(Cl)c3s2)nc1C=O.CNC>>CCn1cc(-c2cc3nccc(Cl)c3s2)nc1CN(C)C -US20040023958A1,3,C#CC1(C2CCCC2)CC(=O)CC(=O)O1.Cc1cccc(I)c1>>Cc1cccc(C#CC2(C3CCCC3)CC(=O)CC(=O)O2)c1 -US04791131,2,CC(=O)OC(C)=O.O=C1Cc2cc(Cl)ccc2N1>>CC(=O)N1C(=O)Cc2cc(Cl)ccc21 -US20140113877A1,2,CCOc1cc2c(cc1OC)C(c1cccc(C(=O)O)c1)=N[C@@H]1CCSC[C@H]21.COc1c(F)cc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)cc1F>>CCOc1cc2c(cc1OC)C(c1cccc(C(=O)N3CCC(n4c(=O)c5sc(-c6ccccc6)cc5n(Cc5cc(F)c(OC)c(F)c5)c4=O)CC3)c1)=N[C@@H]1CCSC[C@H]21 -US20070219210A1,9,CCOC(=O)c1cc(-c2ccc(C)cn2)n(-c2ccc(Cl)nn2)n1>>CCOC(=O)c1cc(-c2ccc(C)cn2)n(-c2cccnn2)n1 -US20140288123A1,6,COC(=O)c1ccc(C(C)Oc2ccccc2)nc1>>CC(Oc1ccccc1)c1ccc(C(=O)O)cn1 -US08691810B2,6,COc1ccc(COC2(c3ncc(-c4c(Cl)cnc5c4cc(-c4cnn(CCN6CCCC6)c4)n5S(=O)(=O)c4ccc(C)cc4)s3)COC2)cc1>>Cc1ccc(S(=O)(=O)n2c(-c3cnn(CCN4CCCC4)c3)cc3c(-c4cnc(C5(O)COC5)s4)c(Cl)cnc32)cc1 -US20060019958A1,2,COc1cc(-c2ccccc2)ccc1C(=O)O.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COc1cc(-c2ccccc2)ccc1C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20060148858A1,8,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CO>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1C=O -US20060122210A1,2,O=C(Cl)c1ccc(-c2ccccc2)cc1.O=C1OC2(CCNC2)c2ccccc21>>O=C1O[C@]2(CCN(C(=O)c3ccc(-c4ccccc4)cc3)C2)c2ccccc21 -US05563158,1,COC(=O)c1cccc(O)c1.N#Cc1ccc(CBr)cc1>>COC(=O)c1cccc(OCc2ccc(C#N)cc2)c1 -US20050181988A1,2,COC(=O)c1ccc(C(=O)O)nc1.COCCOc1ccc(-c2ccc(C(=O)NN)cc2)cc1>>COCCOc1ccc(-c2ccc(C(=O)NNC(=O)c3ccc(C(=O)OC)cn3)cc2)cc1 -US05877317,3,C#CCO.COC(=O)c1ccccc1I>>COC(=O)c1ccccc1C#CCO -US20030083341A1,2,CCOC(=O)c1cc(-c2cccc(Cl)c2)c(OCCO)c(-c2cccc(Cl)c2)c1.NCCCCCCCCc1ccccc1>>O=C(NCCCCCCCCc1ccccc1)c1cc(-c2cccc(Cl)c2)c(OCCO)c(-c2cccc(Cl)c2)c1 -US20040162422A1,1,C#C[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.CO[C@@H]1CC[C@@H](N)CC1>>C#C[C@H]1O[C@@H](n2cnc3c(N[C@@H]4CC[C@@H](OC)CC4)ncnc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O -US20110136859A1,7,CC(C)N1C(=O)c2ccc([N+](=O)[O-])cc2C1=O>>CC(C)N1C(=O)c2ccc(N)cc2C1=O -US08048909B2,1,CN.O=Cc1cc(-c2ccccc2)n(S(=O)(=O)c2ccccc2)c1Cl>>CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2ccccc2)c1Cl -US20120165331A1,9,BrC(Br)(Br)Br.COc1cccc(-c2nn(COCC[Si](C)(C)C)nc2CO)c1>>COc1cccc(-c2nn(COCC[Si](C)(C)C)nc2CBr)c1 -US20050070506A1,1,CCCCCCCCCI.O=Cc1ccc(O)c(OC2CC2)c1>>CCCCCCCCCOc1ccc(C=O)cc1OC1CC1 -US20040097507A1,2,Cc1onc(-c2c(Cl)cncc2Cl)c1C(=O)O.NC1CCCC(CNC(=O)OCc2ccccc2)C1>>Cc1onc(-c2c(Cl)cncc2Cl)c1C(=O)NC1CCCC(CNC(=O)OCc2ccccc2)C1 -US09096586B2,3,CCCC[Sn](CCCC)(CCCC)c1ccnc(-c2ccc3c(cnn3C)c2)n1.COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(Br)sc2c1-c1ccc(Cl)cc1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5c(cnn5C)c4)n3)sc2c1-c1ccc(Cl)cc1 -US20070037796A1,3,NCCNS(=O)(=O)c1cc(Br)cc2cnccc12.c1ccc(B2OCCCO2)cc1>>NCCNS(=O)(=O)c1cc(-c2ccccc2)cc2cnccc12 -US20140336377A1,2,CC(NC(=O)c1cc(N)ncn1)c1ccc(OCC(F)(F)F)nc1.O=C(Cl)C1CC1>>CC(NC(=O)c1cc(NC(=O)C2CC2)ncn1)c1ccc(OCC(F)(F)F)nc1 -US20080064689A1,2,CC(C)(C)OC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)O.NC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1>>CC(C)(C)OC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)NC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1 -US20070212297A1,7,C=Cc1nc(-c2ccccc2)c(CN(Cc2cccc(OCC)c2)Cc2ccc3c(c2)OCCO3)n1CCCC>>CCCCn1c(CC)nc(-c2ccccc2)c1CN(Cc1cccc(OCC)c1)Cc1ccc2c(c1)OCCO2 -US07618978B2,1,CC[C@H](C)Nc1cc(C(=O)OC)cc(Cl)n1.CS(N)(=O)=O>>CC[C@H](C)Nc1cc(C(=O)OC)cc(NS(C)(=O)=O)n1 -US05124069,1,CCCCCCCCOc1ccc(C(=O)O)cc1C#N.CCCCCC[C@@H]1CC[C@H](O)C(=O)O1>>CCCCCCCCOc1ccc(C(=O)O[C@@H]2CC[C@@H](CCCCCC)OC2=O)cc1C#N -US06528543B1,2,CCOC(=O)C(CC1CCCC1)c1ccc([N+](=O)[O-])cc1.CNC(N)=O>>CNC(=O)NC(=O)C(CC1CCCC1)c1ccc([N+](=O)[O-])cc1 -US20060287309A1,1,O=CCCCOc1nc2c(cc1F)CCC(=O)N2.c1ccc2c(N3CCNCC3)cccc2c1>>O=C1CCc2cc(F)c(OCCCCN3CCN(c4cccc5ccccc45)CC3)nc2N1 -US20040097503A1,1,COc1ccc(Cl)c(N)c1.Cc1cc(Cl)nc(-c2ccccn2)n1>>COc1ccc(Cl)c(Nc2cc(C)nc(-c3ccccn3)n2)c1 -US20080207882A1,6,COc1ccsc1C(=O)c1ccc(OC(F)(F)F)cc1>>O=C(c1ccc(OC(F)(F)F)cc1)c1sccc1O -US20050234081A1,3,CC1(C)OB(c2cccc(C(O)C(F)(F)F)c2)OC1(C)C.CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(Br)c1>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2cccc(C(O)C(F)(F)F)c2)c1 -US20100016401A1,2,Cc1ccc(C(=O)O)c(Br)c1.O=C(NC[C@H]1NC[C@H]2C[C@H]21)C(F)(F)F>>Cc1ccc(C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)C(F)(F)F)c(Br)c1 -US20100222299A1,7,COc1cc2c(cc1OCc1ccccc1)CCN=C2C>>COc1cc2c(cc1OCc1ccccc1)CCNC2C -US20140275172A1,7,CCOC(=O)/C=C/c1cc(F)c(OC)cc1CCC(C)C>>CCOC(=O)CCc1cc(F)c(OC)cc1CCC(C)C -US20150239895A1,1,CC(C)(C)OC(=O)CBr.Clc1ccc2[nH]nc(I)c2n1>>CC(C)(C)OC(=O)Cn1nc(I)c2nc(Cl)ccc21 -US08445692B2,1,Cc1noc(C)c1Cn1cc(N2C(=O)NC(C)(C)C2=O)cn1.Fc1ccc(CBr)cc1>>Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(F)cc3)C(C)(C)C2=O)cn1 -US06765006B2,1,C1CNCCN1.ClCc1nc(-c2ccc3c(c2)OCO3)c2cc3c(cc2n1)OCO3>>c1cc2c(cc1-c1nc(CN3CCNCC3)nc3cc4c(cc13)OCO4)OCO2 -US05565485,2,CC(C)c1ccc(S(N)(=O)=O)cc1.CCCc1c(OC(C(=O)O)c2ccc3c(c2)OCO3)ccc(C(C)(C)C)c1CO[SiH](C)C>>CCCc1c(OC(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)ccc(C(C)(C)C)c1CO[SiH](C)C -US06825191B2,2,CCOC(=O)CNCc1ccc(Br)cc1[N+](=O)[O-].O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)CN(Cc1ccc(Br)cc1[N+](=O)[O-])C(=O)c1ccc(Cl)cc1 -US20090054460A1,1,C1CCNCC1.Cc1ccc(S(=O)(=O)N2CCNC(=O)C2CC(=O)N[C@@H]2CCCc3c2cnn3CCOS(C)(=O)=O)cc1>>Cc1ccc(S(=O)(=O)N2CCNC(=O)C2CC(=O)N[C@@H]2CCCc3c2cnn3CCN2CCCCC2)cc1 -US20150080393A1,1,Cc1ccn(-c2cc(Br)ccc2[C@@H](O)C(F)(F)F)n1.Nc1nc(Cl)cc(Cl)n1>>Cc1ccn(-c2cc(Br)ccc2[C@@H](Oc2cc(Cl)nc(N)n2)C(F)(F)F)n1 -US20100093705A1,1,O=C(O)CCl.O=C(O)c1ccccc1O>>O=C(O)COc1ccccc1C(=O)O -US20080027050A1,7,N#Cc1ccnc(OCC2CCOCC2)c1>>NCc1ccnc(OCC2CCOCC2)c1 -US05541200,1,COc1ccc(CCBr)cc1.O=C(c1nc2ccccc2s1)C1CCNCC1>>COc1ccc(CCN2CCC(C(=O)c3nc4ccccc4s3)CC2)cc1 -US04001271,1,CC(C)N.O=C1c2ccccc2C(OCCCl)N1c1ccccc1>>CC(C)NCCOC1c2ccccc2C(=O)N1c1ccccc1 -US20080045496A1,2,NC1CC1.O=C(O)c1cc([N+](=O)[O-])n[nH]1>>O=C(NC1CC1)c1cc([N+](=O)[O-])n[nH]1 -US07196111B2,9,NC(=O)c1cc2[nH]c(-c3ccc(OCc4ccccc4)cc3)c(C3CCCCC3)c(=O)n2n1>>N#Cc1cc2[nH]c(-c3ccc(OCc4ccccc4)cc3)c(C3CCCCC3)c(=O)n2n1 -US20150057240A1,6,CC(=O)NCCc1ccc(OCc2ccccc2)cc1-c1ccccc1>>CC(=O)NCCc1ccc(O)cc1-c1ccccc1 -US06528504B2,7,COc1ccc(CCN2CC[C@H](OC(=O)c3ccc([N+](=O)[O-])cc3)C2)cc1>>COc1ccc(CCN2CC[C@H](O)C2)cc1 -US07964591B2,2,Nc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1.O=C(O)COCCC(F)(F)F>>O=C(COCCC(F)(F)F)Nc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 -US07446103B2,2,Fc1ccc2c(c1)CNC2.O=C(Cl)c1ccc(OCCCN2CCCCC2)cc1>>O=C(c1ccc(OCCCN2CCCCC2)cc1)N1Cc2ccc(F)cc2C1 -US05424308,6,COC(=O)CNC(=O)C(C#N)C(=O)c1nn(-c2ccccc2)c2c1Cc1ccccc1-2>>N#CC(C(=O)NCC(=O)O)C(=O)c1nn(-c2ccccc2)c2c1Cc1ccccc1-2 -US05756522,1,FC(F)(F)c1cc(Cl)c(-n2cnc(S)n2)c(Cl)c1.FC(F)Cl>>FC(F)Sc1ncn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1 -US05985281,2,N[C@@H](CC(=O)O)C(=O)O.O=C(O)CNC(=O)c1ccccc1>>O=C(O)C[C@H](NC(=O)CNC(=O)c1ccccc1)C(=O)O -US20150031674A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)CCl)CC1.CSc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3C)c(=O)[nH]c2n1>>CSc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3C)c(=O)n(CC(=O)N3CCN(C(=O)OC(C)(C)C)CC3)c2n1 -US20140073620A1,6,CC(C)(C)OC(=O)N1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1>>NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)nc3)ncc2C(F)(F)F)CC1 -US20100075965A1,2,Nc1cn2nc(Cl)ccc2n1.O=C(Cl)CBr>>O=C(CBr)Nc1cn2nc(Cl)ccc2n1 -US06313127B1,1,N#Cc1ccc(F)cc1.c1cc(N2CCNCC2)ccn1>>N#Cc1ccc(N2CCN(c3ccncc3)CC2)cc1 -US07229987B2,2,NNC(=O)c1ccc(O)cc1.O=C(O)CCOCCOc1ccccc1>>O=C(CCOCCOc1ccccc1)NNC(=O)c1ccc(O)cc1 -US20150259366A1,6,COC(=O)c1cc(N(Cc2ccc(OC)cc2)C(=O)c2ccc(Oc3ccccc3)cc2)ccc1O>>COc1ccc(CN(C(=O)c2ccc(Oc3ccccc3)cc2)c2ccc(O)c(C(=O)O)c2)cc1 -US08063046B2,2,COc1ccc(C(N)=O)cc1C(=O)O.Nc1ccccc1Cl>>COc1ccc(C(N)=O)cc1C(=O)Nc1ccccc1Cl -US20150025087A1,2,COc1ncnc(Cn2cc(C(=O)O)c3ncccc32)c1C.NCCF>>COc1ncnc(Cn2cc(C(=O)NCCF)c3ncccc32)c1C -US20090149456A1,7,O=C(NCc1cccc([N+](=O)[O-])c1)C(F)(F)F>>Nc1cccc(CNC(=O)C(F)(F)F)c1 -US20030092720A1,1,CI.Cc1ccnc([N+](=O)[O-])c1O>>COc1c(C)ccnc1[N+](=O)[O-] -US20040006141A1,6,CCCCC(Cc1ccc(OCCNC(=O)c2c[nH]c3ccccc23)cc1)C(=O)OCC>>CCCCC(Cc1ccc(OCCNC(=O)c2c[nH]c3ccccc23)cc1)C(=O)O -US08026272B2,2,NCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O.O=CO>>O=CNCC(=O)N1C[C@H](NC(=O)c2ccccc2)C[C@H]1C(=O)O -US20120028959A1,7,COC(=O)c1cccc([N+](=O)[O-])c1N>>COC(=O)c1cccc(N)c1N -US20100297075A1,7,O=C1NC(=O)C(c2cn3c4c(cccc24)CCC3)=C1c1c[nH]c2ccccc12>>O=C1NC(=O)[C@@H](c2c[nH]c3ccccc23)[C@@H]1c1cn2c3c(cccc13)CCC2 -US08252795B2,7,COc1c(F)cc(Br)cc1[N+](=O)[O-]>>COc1c(N)cc(Br)cc1F -US07977512B2,1,CCCN(CCC)CCCCNCc1ccc(C#N)cc1.O=Cc1ccc(Br)cc1>>CCCN(CCC)CCCCN(Cc1ccc(Br)cc1)Cc1ccc(C#N)cc1 -US20060142337A1,1,CC(C)OC(=O)CBr.C[C@@H](O[C@H]1CCN(C(=O)C2CCNCC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(C)OC(=O)CN1CCC(C(=O)N2CC[C@H](O[C@H](C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](c3ccccc3)C2)CC1 -US20110034469A1,2,C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C.N[C@H](C(=O)N1C[C@H]2C[C@@H](O)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCC(F)(F)CC1>>C[C@@H](C(=O)N[C@H](C(=O)N1C[C@H]2C[C@@H](O)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCC(F)(F)CC1)N(C)C(=O)OC(C)(C)C -US08828987B2,6,COC(=O)c1cc(C(F)(F)F)cnc1N1CC(Oc2cc(C)on2)C1>>Cc1cc(OC2CN(c3ncc(C(F)(F)F)cc3C(=O)O)C2)no1 -US06479534B1,4,NNc1ccccc1.O=C1CCCC1>>c1ccc2c3c([nH]c2c1)CCC3 -US20120252805A1,3,Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(Br)c(C)sc2n1.OB(O)c1ccc2cc[nH]c2c1>>Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(-c3ccc4cc[nH]c4c3)c(C)sc2n1 -US08426411B2,6,CCOC(=O)[C@H]1C[C@@H](O)C[C@H]1CC>>CC[C@@H]1C[C@H](O)C[C@@H]1C(=O)O -US06232318B1,6,CC(C)(C)OC(=O)NCCCn1c(=O)c(-c2ccccc2)cn(Cc2ccccc2)c1=O>>NCCCn1c(=O)c(-c2ccccc2)cn(Cc2ccccc2)c1=O -US07803822B2,2,CCCc1c(C(=O)O)nnn1-c1ccc(C(=O)NCCc2ccccc2)cc1.NC1CC1>>CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(C(=O)NCCc2ccccc2)cc1 -US07915268B2,6,COC(OC)c1ccnc(N)n1>>Nc1nccc(C=O)n1 -US20040167123A1,2,CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(N)ccc3N2)c(O)c2cccnc21.O=S(=O)(Cl)c1cccs1>>CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)c4cccs4)ccc3N2)c(O)c2cccnc21 -US20140058098A1,2,CC(C)n1ncnc1-c1cc2n(n1)-c1cc(C(=O)O)ccc1OCC2.OC1CCNCC1>>CC(C)n1ncnc1-c1cc2n(n1)-c1cc(C(=O)N3CCC(O)CC3)ccc1OCC2 -US07666878B2,6,COC(=O)Cc1c(C)n(Cc2ccc([N+](=O)[O-])cc2)c2ncccc12>>Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc([N+](=O)[O-])cc1 -US20150252000A1,7,N#Cc1ccc2[nH]cc(C(=O)CCCCl)c2c1>>N#Cc1ccc2[nH]cc(CCCCCl)c2c1 -US04381265,1,C=CC#N.CN(CCO)c1ccccc1>>CN(CCOCCC#N)c1ccccc1 -US05739129,6,COc1ccc(C(C(N)=O)(C(C)C)N2C(=O)C(NC(=O)Nc3cccc(C(=O)OC(C)(C)C)c3)C(=O)N(c3cccnc3)c3cc(F)ccc32)cc1>>COc1ccc(C(C(N)=O)(C(C)C)N2C(=O)C(NC(=O)Nc3cccc(C(=O)O)c3)C(=O)N(c3cccnc3)c3cc(F)ccc32)cc1 -US20100166706A1,2,CCC[C@H](NC(=O)C1CC(Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)C=C1C(=O)O)C(=O)OC(C)(C)C.COC(=O)C(NC(=O)C(N)C(C)C)C1CCCCC1>>CCC[C@H](NC(=O)[C@H]1C[C@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)C=C1C(=O)N[C@H](C(=O)N[C@H](C(=O)OC)C1CCCCC1)C(C)C)C(=O)OC(C)(C)C -US20080269193A1,1,CCc1nn(-c2ccc(C#N)c(Br)c2)c2c1C(=O)CC(C)(C)C2.N[C@H]1CCCC[C@@H]1OCc1ccccc1>>CCc1nn(-c2ccc(C#N)c(N[C@H]3CCCC[C@@H]3OCc3ccccc3)c2)c2c1C(=O)CC(C)(C)C2 -US05021449,2,CCN1CCCC1CN.COC(=O)c1sc(C(=O)OC)c(C(=O)OC)c1OC>>CCN1CCCC1CNC(=O)c1sc(C(=O)OC)c(C(=O)OC)c1OC -US20040038239A1,1,CCCC(=O)c1ccc(Br)cc1O.CI>>CCCC(=O)c1ccc(Br)cc1OC -US07511133B2,7,O=[N+]([O-])c1ccccc1S(=O)(=O)N1CC=CC1>>Nc1ccccc1S(=O)(=O)N1CC=CC1 -US08518972B2,7,COC(=O)c1cc(CN2CCOCC2)co1>>OCc1cc(CN2CCOCC2)co1 -US06048864,1,COc1cc(F)c(C#N)c(F)c1.OCC(F)(F)F>>COc1cc(F)c(C#N)c(OCC(F)(F)F)c1 -US20140155391A1,2,CS(=O)(=O)Oc1cc(C(=O)O)ccc1OCc1ccccc1.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>CS(=O)(=O)Oc1cc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)ccc1OCc1ccccc1 -US05371064,2,CO.O=C(O)c1ccc(Cl)c(Cl)c1Sc1ccccc1>>COC(=O)c1ccc(Cl)c(Cl)c1Sc1ccccc1 -US20060128755A1,6,CCOC(=O)CCCN(CC)c1cccc(C)c1>>CCN(CCCC(=O)O)c1cccc(C)c1 -US05716944,2,CCOP(=O)(Cc1ccc(N)cc1)OCC.O=C(O)C1=Cc2cc(C3CCCCC3)ccc2CC1>>CCOP(=O)(Cc1ccc(NC(=O)C2=Cc3cc(C4CCCCC4)ccc3CC2)cc1)OCC -US20030225064A1,2,C1COCCN1.CS(=O)(=O)c1ccc(-n2nc(C(=O)O)cc2-c2ccc(-c3ccco3)cc2)cc1F>>CS(=O)(=O)c1ccc(-n2nc(C(=O)N3CCOCC3)cc2-c2ccc(-c3ccco3)cc2)cc1F -US07572801B2,1,CCOC(=O)CI.OCCc1cccc(F)c1>>CCOC(=O)COCCc1cccc(F)c1 -US20150210698A1,6,CC(C)(C)OC(=O)N1CCC(n2nc(I)c3c(N)ncnc32)CC1>>Nc1ncnc2c1c(I)nn2C1CCNCC1 -US08026255B2,1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1cc2ccccc2c(Cl)n1>>CC(C)(C)OC(=O)N1CCC(Nc2nc(Cl)cc3ccccc23)CC1 -US20070191385A1,3,O=C1CN(c2ccc(-n3cc(-c4ccc(Cl)cc4Cl)nc3Cc3ccc(Br)cc3)cc2)S(=O)(=O)N1.OB(O)c1ccc(Cl)nc1>>O=C1CN(c2ccc(-n3cc(-c4ccc(Cl)cc4Cl)nc3Cc3ccc(-c4ccc(Cl)nc4)cc3)cc2)S(=O)(=O)N1 -US20120101082A1,1,CC(C)(C)CC=O.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(CCC(C)(C)C)CC1 -US20130274244A1,2,COCCOc1ccn2c(C(=O)O)cnc2c1.Nc1cccc2c1cnn2Cc1ccccc1>>COCCOc1ccn2c(C(=O)Nc3cccc4c3cnn4Cc3ccccc3)cnc2c1 -US20110021479A1,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1.COCCOc1cc(OC)ccc1-c1ncnc2c(C(=O)O)c[nH]c12>>COCCOc1cc(OC)ccc1-c1ncnc2c(C(=O)N[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)c[nH]c12 -US20140171430A1,2,COc1cc(OC)nc(N2CC3CNCC3C2)n1.O=C(O)c1c(F)cccc1-n1nccn1>>COc1cc(OC)nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)n1 -US09040522B2,2,CCOCCN.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>CCOCCNC(=O)c1ccc(-n2ncc(-c3ccc(C#N)cc3C)c2O)nc1 -US20130184241A1,1,ClCc1cccnc1.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(OCc2cccnc2)cc1 -US20090192136A1,2,CC1CN(C(=O)OC(C)(C)C)CCN1.CS(=O)(=O)c1ccc(I)c(C(=O)O)c1>>CC1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1cc(S(C)(=O)=O)ccc1I -US07332511B2,2,CS(=O)(=O)Cl.Nc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1>>CS(=O)(=O)Nc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1 -US20070213364A1,1,CC(C)(C)c1cc(OCc2ccccc2)n(Cc2ccc(CO)cc2)n1.CCOC(=O)CCc1ccc(O)cc1F>>CCOC(=O)CCc1ccc(OCc2ccc(Cn3nc(C(C)(C)C)cc3OCc3ccccc3)cc2)cc1F -US07585883B2,2,O=C(Cl)c1cccc(Cl)c1.OCCBr>>O=C(OCCBr)c1cccc(Cl)c1 -US05157035,1,Cc1cccc(N2CCN(c3ccc(Cl)nn3)CC2)c1.Oc1ccccc1>>Cc1cccc(N2CCN(c3ccc(Oc4ccccc4)nn3)CC2)c1 -US05840724,1,BrC1CCCC1.COC(=O)c1ccc(SC)c(O)c1>>COC(=O)c1ccc(SC)c(OC2CCCC2)c1 -US04027026,2,CN=C=S.NCCSCc1ncccc1N>>CNC(=S)NCCSCc1ncccc1N -US20060199966A1,2,CC[C@H](O)C(=O)O.O=C(N[C@@H]1Cc2ccccc2[C@H]1NCCOC1CCCCO1)c1cc2cc(Cl)ccc2[nH]1>>CC[C@H](O)C(=O)N(CCOC1CCCCO1)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1 -US20080009509A1,2,COC(=O)C(N)Cc1ccccc1.COCC(=O)Cl>>COCC(=O)N[C@@H](Cc1ccccc1)C(=O)OC -US20140243286A1,2,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)O)c1nnc(C)n1-2.NCc1cccc(O)c1O>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCc1cccc(O)c1O)c1nnc(C)n1-2 -US20150266881A1,6,COC(=O)c1cccc([C@@H]2C[C@H]2NC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1cccc(C(=O)O)c1 -US08754085B2,10,Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(C(=O)OC(C)(C)C)CCC3)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(C(=O)OC(C)(C)C)CCC3Br)cc1 -US20100273806A1,3,O=C(O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(Br)cc(OC(F)(F)F)c4)n3)cc21.OB(O)c1cccnc1F>>O=C(O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(OC(F)(F)F)cc(-c5cccnc5F)c4)n3)cc21 -US20080269214A1,2,COC(=O)c1cnc(-c2ccc([NH3+])cc2)s1.Cc1[nH]c(C(=O)Cl)c(Cl)c1Cl>>COC(=O)c1cnc(-c2ccc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)cc2)s1 -US20150252008A1,3,COc1c(C2CCC2)ccc(B(O)O)c1F.Nc1ncc(Br)cn1>>COc1c(C2CCC2)ccc(-c2cnc(N)nc2)c1F -US04910318,6,CNCC1CCSc2c1n(Cc1ccccc1)c1ccccc21>>CNCC1CCSc2c1[nH]c1ccccc21 -US08871361B2,1,Brc1cccc(-c2nccn2-c2ccccc2)c1.c1ccc(Nc2cccc(-c3nccn3-c3ccccc3)c2)cc1>>c1ccc(N(c2cccc(-c3nccn3-c3ccccc3)c2)c2cccc(-c3nccn3-c3ccccc3)c2)cc1 -US20100041642A1,6,CN1CCN(C(=O)c2cc(C(C)(C)C)sc2NC(=O)OC(C)(C)C)C(C)(C)C1=O>>CN1CCN(C(=O)c2cc(C(C)(C)C)sc2N)C(C)(C)C1=O -US20090298899A1,3,CCOC(=O)CCc1cccc(NC(=O)c2cccc(Br)n2)c1.OB(O)c1ccccc1>>CCOC(=O)CCc1cccc(NC(=O)c2cccc(-c3ccccc3)n2)c1 -US06541505B1,1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(Cl)n4)cc3)cc12>>CC(C)(C)OC(=O)N1CCN(c2nccc(-c3ccc(C(=O)NCCc4ccc5[nH]cc(C#N)c5c4)cc3)n2)CC1 -US20070082896A1,6,CC[C@@H]1C[C@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2cc(C(F)(F)F)ccc2N1C(=O)CCCC(=O)OC>>CC[C@@H]1C[C@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2cc(C(F)(F)F)ccc2N1C(=O)CCCC(=O)O -US04247551,4,CC(=O)CCC(C)=O.CC1CN(c2ccc(NN)nn2)CC(C)O1>>Cc1ccc(C)n1Nc1ccc(N2CC(C)OC(C)C2)nn1 -US20120264750A1,7,COc1ccc(O)c([N+](=O)[O-])c1>>COc1ccc(O)c(N)c1 -US04751295,6,CC(C)(C)OC(=O)Nc1nc(C(=NOC2CCCC2)C(=O)O)ns1>>Nc1nc(C(=NOC2CCCC2)C(=O)O)ns1 -US20070208166A1,7,O=C(NCC1COc2ccccc2O1)c1ccc(Nc2ccccc2C(=O)O)c([N+](=O)[O-])c1>>Nc1cc(C(=O)NCC2COc3ccccc3O2)ccc1Nc1ccccc1C(=O)O -US20100022598A1,7,CC(=CC(=O)OCc1ccccc1)C(F)(F)F>>CC(=CCO)C(F)(F)F -US20140296260A1,1,C[C@H](N)c1nc2cccc(F)c2c(=O)n1-c1cccc(OCC(F)(F)F)c1.Clc1ncnc2[nH]ccc12>>C[C@H](Nc1ncnc2[nH]ccc12)c1nc2cccc(F)c2c(=O)n1-c1cccc(OCC(F)(F)F)c1 -US20120184736A1,1,Cc1cccc(C2CC2)c1O.Oc1cc(Cl)nnc1Cl>>Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O -US08604029B2,1,C1CSCCN1.O=[N+]([O-])c1ccc(Cl)cc1>>O=[N+]([O-])c1ccc(N2CCSCC2)cc1 -US20030212276A1,1,COc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1F.O=S1(=O)CCN(CCCO)CC1>>COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCS(=O)(=O)CC4)c(OC)cc23)c(Cl)cc1Cl -US20090192139A1,6,CC(C)(C)OC(=O)NC1CN(Cc2cccc(F)c2F)CCN(CC(F)(F)F)C1=O>>NC1CN(Cc2cccc(F)c2F)CCN(CC(F)(F)F)C1=O -US08324216B2,1,CI.COc1cc(N2CCN(C(=O)OC(C)(C)C)[C@@H](CO)C2)ccc1Cl>>COCC1CN(c2ccc(Cl)c(OC)c2)CCN1C(=O)OC(C)(C)C -US20120309739A1,6,Cn1c(N2CC[C@H](O)C2)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2c1=O>>Cn1c(N2CC[C@H](O)C2)nc2oc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)c2c1=O -US20070276138A1,6,COC(Cc1ccc(OCCO[Si](C)(C)C(C)(C)C)cc1)C(=O)O>>CO[C@@H](Cc1ccc(OCCO)cc1)C(=O)O -US20110183964A1,6,COC(Cc1c(C(C)(C)C)[nH]c2cc([N+](=O)[O-])ccc12)OC>>CC(C)(C)c1[nH]c2cc([N+](=O)[O-])ccc2c1CC=O -US05795886,7,C[C@@H]1Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2)=NN1c1nc2ccccc2[nH]1)OCO3>>C[C@@H]1Cc2cc3c(cc2C(c2ccc(N)cc2)=NN1c1nc2ccccc2[nH]1)OCO3 -US04638070,3,CC1CCc2ccccc2S1.CCC(=O)Cl>>CCC(=O)c1ccc2c(c1)CCC(C)S2 -US20080306089A1,6,CC(C)(C)OC(=O)N1CC(n2nnc(-c3ccc(F)cc3F)n2)CC1C(=O)N1CCN(c2ccccc2C#N)CC1>>N#Cc1ccccc1N1CCN(C(=O)[C@@H]2C[C@H](n3nnc(-c4ccc(F)cc4F)n3)CN2)CC1 -US08329716B2,1,COCCc1c[nH]c2nccc(Oc3ccc(N)cc3F)c12.Nc1nc(Cl)cc(C(F)(F)F)n1>>COCCc1c[nH]c2nccc(Oc3ccc(Nc4cc(C(F)(F)F)nc(N)n4)cc3F)c12 -US20080153810A1,7,O=[N+]([O-])c1ccc2[nH]nc(-c3ncco3)c2c1>>Nc1ccc2[nH]nc(-c3ncco3)c2c1 -US20100234395A1,9,COC(=O)C(C(=O)c1ccc(C(C)(C)C)cc1)c1ccc(OC)cc1>>COc1ccc(CC(=O)c2ccc(C(C)(C)C)cc2)cc1 -US20120053197A1,3,CC(C)c1ccc([Mg+])cc1.CC1(C)Cc2nc(C3CCCC3)c(C=O)c(I)c2[C@@H](O[Si](C)(C)C(C)(C)C)C1>>CC(C)c1ccc(C(O)c2c(C3CCCC3)nc3c(c2I)[C@@H](O[Si](C)(C)C(C)(C)C)CC(C)(C)C3)cc1 -US20050043544A1,7,CNC(=O)c1ccc2cc([C@@](O)(CC(=O)OC(C)(C)C)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2c1>>CNC(=O)c1ccc2cc([C@@](O)(CCO)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2c1 -US20130217664A1,7,CN(c1cc2c(cn1)ncn2C)c1ccc(C2=CCN(C(=O)OC(C)(C)C)CC2)cc1OC(F)F>>CN(c1cc2c(cn1)ncn2C)c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2)cc1OC(F)F -US20050250774A1,9,Fc1nc(OCCN2CCOCC2)c(F)c(N2CCOCC2)c1F.NN>>NNc1nc(OCCN2CCOCC2)c(F)c(N2CCOCC2)c1F -US20070049596A1,9,[N-]=[N+]=NCC1=CC[C@@H](c2ccc(Cl)cc2Cl)[C@H]([N+](=O)[O-])C1>>NCC1=CC[C@@H](c2ccc(Cl)cc2Cl)[C@H]([N+](=O)[O-])C1 -US09126998B2,1,O=C(CCBr)Nc1ccc(F)cc1>>O=C1CCN1c1ccc(F)cc1 -US20140336185A1,6,COC(=O)c1ccc(NC(=O)Cc2ccc(OC)cc2C(F)(F)F)cn1>>COc1ccc(CC(=O)Nc2ccc(C(=O)O)nc2)c(C(F)(F)F)c1 -US08796256B2,1,C=O.O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CCNC[C@H]1F>>CN1CC[C@@H](N2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)[C@H](F)C1 -US06096895,9,CCOP(=O)(OCC)C(Cl)(Cl)C(=O)OC(C)(C)C>>CCOP(=O)(OCC)C(Cl)C(=O)OC(C)(C)C -US20020128308A1,1,O=C1CSC(=O)N1.O=[N+]([O-])c1ccc(CBr)cc1>>O=C1CSC(=O)N1Cc1ccc([N+](=O)[O-])cc1 -US20090221555A1,1,COc1cc2c(cc1N)CCN(CC(=O)N1CCOCC1)CC2.NC(=O)[C@@H]1[C@H](Nc2nc(Cl)ncc2Cl)[C@H]2C=C[C@@H]1C2>>COc1cc2c(cc1Nc1ncc(Cl)c(N[C@@H]3[C@H]4C=C[C@H](C4)[C@@H]3C(N)=O)n1)CCN(CC(=O)N1CCOCC1)CC2 -US20120101082A1,4,CC(N)=S.O=C1c2ccccc2N(C(=O)c2ccccc2)CCC1Br>>Cc1nc2c(s1)CCN(C(=O)c1ccccc1)c1ccccc1-2 -US20140107109A1,6,Cc1nc2c(Nc3ccc(F)c([C@]4(C)CS(=O)(=O)C(C)(C)C(NC(=O)OC(C)(C)C)=N4)c3)cccc2s1>>Cc1nc2c(Nc3ccc(F)c([C@]4(C)CS(=O)(=O)C(C)(C)C(N)=N4)c3)cccc2s1 -US20100331385A1,6,CC(=O)n1ncc2cc(Oc3ccc(F)cc3C#N)ccc21>>N#Cc1cc(F)ccc1Oc1ccc2[nH]ncc2c1 -US20100048551A1,3,NC(=O)c1cnc(N)c2c1sc1ccc(Cl)cc12.OB(O)c1ccccc1>>NC(=O)c1cnc(N)c2c1sc1ccc(-c3ccccc3)cc12 -US04916148,7,CC1(C)C(=O)Oc2ccc3cc([N+](=O)[O-])c(Cn4cncn4)cc3c21>>CC1(C)C(=O)Oc2ccc3cc(N)c(Cn4cncn4)cc3c21 -US20140228361A1,7,C#Cc1cccc(Nc2ncnc3cc(OC)c(OC(C)=O)cc23)c1>>C#Cc1cccc(Nc2ncnc3cc(OC)c(O)cc23)c1 -US20040097733A1,1,CCOC(=O)c1ccc(Nc2cc3c(cc2C)C(C)=CCC3(C)C)cc1.O=CC1CC1>>CCOC(=O)c1ccc(N(CC2CC2)c2cc3c(cc2C)C(C)=CCC3(C)C)cc1 -US20020193367A1,3,CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(I)cc1[N+](=O)[O-].OB(O)c1ccccc1F>>CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(-c2ccccc2F)cc1[N+](=O)[O-] -US20060063940A1,1,CCN(CC)CCCOc1ccc(N)cc1.Cc1cccc2c1C(=CO)C(=O)N2>>CCN(CC)CCCOc1ccc(NC=C2C(=O)Nc3cccc(C)c32)cc1 -US20120065195A1,3,CN1C(=O)C2(CC(C)(C)C(F)(F)c3ccc(Br)cc32)N=C1N.OB(O)c1cncnc1>>CN1C(=O)C2(CC(C)(C)C(F)(F)c3ccc(-c4cncnc4)cc32)N=C1N -US20100256097A1,1,CI.OCCc1cn[nH]c1>>Cn1cc(CCO)cn1 -US20070155716A1,1,CC1(C)Cc2nc(-c3cc(Cl)ccc3F)nc(I)c2C1.Cc1cnccc1N>>Cc1cnccc1Nc1nc(-c2cc(Cl)ccc2F)nc2c1CC(C)(C)C2 -US20120142922A1,1,COCCN.O=[N+]([O-])c1cc(-c2ccccc2)ccc1F>>COCCNc1ccc(-c2ccccc2)cc1[N+](=O)[O-] -US06316494B1,6,COc1ccc2c(c1)OC[C@@H](c1ccc(C)cc1)[C@H]2c1ccc(OCCN2CCCCC2)cc1>>Cc1ccc([C@@H]2COc3cc(O)ccc3[C@@H]2c2ccc(OCCN3CCCCC3)cc2)cc1 -US20120040954A1,7,COc1cc(OC)c2c(=O)[nH]c(-c3ccc(C4=CCN(C(=O)OC(C)(C)C)CC4)cc3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc3)nc2c1 -US05175281,1,CNCCNC.Clc1ccccn1>>CNCCN(C)c1ccccn1 -US07553867B2,7,COCOc1cccc(C=O)c1>>COCOc1cccc(CO)c1 -US05049548,7,O=C1CN2CCC1CC2>>OC1CN2CCC1CC2 -US20130274479A1,1,NO.O=C(Cl)OCc1ccccc1>>O=C(NO)OCc1ccccc1 -US04046900,3,CC(=O)N1CCC(C(=O)Cl)CC1.Fc1ccccc1>>CC(=O)N1CCC(C(=O)c2ccc(F)cc2)CC1 -US06352982B1,3,CC(C)(C)OC(=O)NCCc1cccc(Br)c1.CON(C)C(=O)c1cc(Cl)ccc1N>>CC(C)(C)OC(=O)NCCc1cccc(C(=O)c2cc(Cl)ccc2N)c1 -US20140288066A1,1,C[C@H]1COCCN1.Clc1nc(Cl)c2c(n1)CCSC2>>C[C@H]1COCCN1c1nc(Cl)nc2c1CSCC2 -US20080167354A1,6,CCOC(=O)C1(CO[C@@H]2CCC[C@H](OCc3nc(-c4cccc(C)c4)oc3C)C2)CC1>>Cc1cccc(-c2nc(CO[C@H]3CCC[C@@H](OCC4(C(=O)O)CC4)C3)c(C)o2)c1 -US20140243290A1,7,CC(C)(C)OC(=O)N1CCC(Oc2ccnc(Nc3cc(-c4cnc(C5(O)CCC5)s4)cc([N+](=O)[O-])c3)n2)CC1>>CC(C)(C)OC(=O)N1CCC(Oc2ccnc(Nc3cc(N)cc(-c4cnc(C5(O)CCC5)s4)c3)n2)CC1 -US20040034038A1,6,CC(C)(C)OC(=O)NCCCOc1ccc(Cl)cc1NC(=O)Nc1cnc(C#N)cn1>>N#Cc1cnc(NC(=O)Nc2cc(Cl)ccc2OCCCN)cn1 -US20050203086A1,3,C#CCNC(=O)OC(C)(C)C.COC(=O)c1ccc(Br)s1>>COC(=O)c1ccc(C#CCNC(=O)OC(C)(C)C)s1 -US05166204,3,CCC(=O)c1cc2cc(OC)ccc2n1COC.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(CC)c1cc2cc(OC)ccc2n1COC -US20030187023A1,9,O=S(=O)(Cl)c1ccc2cc(Cl)ccc2c1>>Sc1ccc2cc(Cl)ccc2c1 -US20090281073A1,1,CC(C)(C)OC(=O)N1CCC2(CC1)CNC2.Cc1cc(Nc2nc(Cl)nc3ncccc23)[nH]n1>>Cc1cc(Nc2nc(N3CC4(CCN(C(=O)OC(C)(C)C)CC4)C3)nc3ncccc23)[nH]n1 -US08003785B2,1,CCN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21.Nc1ccc(C(=O)NC2CCOCC2)cc1>>CCN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCOCC4)cc3)ncc21 -US07572809B2,1,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.Nc1ccc(Cl)cc1>>COc1ccc2c(Nc3ccc(Cl)cc3)nc(Nc3cc(C)[nH]n3)cc2c1 -US20140288045A1,1,COC(=O)CS.COc1cc(Cl)c(C2CC2)cc1I>>COC(=O)CSc1cc(C2CC2)c(Cl)cc1OC -US07858796B2,1,CCN.NC(=O)c1cc(-c2cccc(C=O)c2)cc2c(C3CCN(S(=O)(=O)CCCN4CCCC4)CC3)c[nH]c12>>CCNCc1cccc(-c2cc(C(N)=O)c3[nH]cc(C4CCN(S(=O)(=O)CCCN5CCCC5)CC4)c3c2)c1 -US20020049246A1,3,Cc1nn(C)c(C)c1Br.Nc1nc2ccccc2n1-c1cccc(B2OCCCO2)c1>>Cc1nn(C)c(C)c1-c1cccc(-n2c(N)nc3ccccc32)c1 -US20100317657A1,3,CN(C)C(=O)c1ccc(B(O)O)cc1.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(-c4ccc(C(=O)N(C)C)cc4)cc3c21 -US20150238500A1,3,CCOC(=O)Cn1cc(I)cc1C=O.OB(O)c1ccccc1>>CCOC(=O)Cn1cc(-c2ccccc2)cc1C=O -US20060106048A1,6,COC(=O)COc1cccc(C2=NC(C)(C)Cc3cc(OC)c4c(c32)CC(C)(C)O4)c1>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(OCC(=O)O)c1)=NC(C)(C)C2 -US08101775B2,3,CC(C)C[Zn+].CCOC(=O)c1ccc(Br)c(Cl)c1>>CCOC(=O)c1ccc(CC(C)C)c(Cl)c1 -US06022492,1,CCCCCCCCBr.CCCCCCCCCCCCOc1ccc(-c2ncc(-c3ccc(O)c(F)c3F)cn2)cn1>>CCCCCCCCCCCCOc1ccc(-c2ncc(-c3ccc(OCCCCCCCC)c(F)c3F)cn2)cn1 -US20090029960A1,1,CC(C)(C)OC(=O)N[C@@H](Cc1cccc(O)c1)[C@H](O)CNC1(c2cc(C(C)(C)C)ccn2)CC1.COC(=O)c1cc(C)nc(OCCCCOS(C)(=O)=O)c1>>COC(=O)c1cc(C)nc(OCCCCOc2cccc(C[C@H](NC(=O)OC(C)(C)C)[C@H](O)CNC3(c4cc(C(C)(C)C)ccn4)CC3)c2)c1 -US20090054681A1,3,C=C[Mg+].O=Cc1cccc(Cl)c1O>>C=CC(O)c1cccc(Cl)c1O -US20150087626A1,1,COC(=O)c1ccc(C2(NC(=O)[C@H]3C[C@@H]4C[C@@H]4N3)CC2)cc1.FC(F)(F)c1ccc(CBr)cc1>>COC(=O)c1ccc(C2(NC(=O)[C@H]3C[C@@H]4C[C@@H]4N3Cc3ccc(C(F)(F)F)cc3)CC2)cc1 -US05190975,7,O=C(O)Cc1ccc2c(c1)CC(NS(=O)(=O)c1ccc(Cl)cc1)C2>>O=S(=O)(NC1Cc2ccc(CCO)cc2C1)c1ccc(Cl)cc1 -US20050261347A1,9,[N-]=[N+]=NCC1Cc2cc(F)cc(-c3ccccc3C(F)(F)F)c2O1>>NCC1Cc2cc(F)cc(-c3ccccc3C(F)(F)F)c2O1 -US07132456B2,1,CCOC(=O)c1ccc(-c2ccc(CSCCO)cc2)cc1.Oc1ccccc1>>CCOC(=O)c1ccc(-c2ccc(CSCCOc3ccccc3)cc2)cc1 -US20070265256A1,3,CC1(C)OB(c2ccc(OCC3CC3)nc2)OC1(C)C.COc1cc2nncc(Br)c2cc1OC>>COc1cc2nncc(-c3ccc(OCC4CC4)nc3)c2cc1OC -US07026335B2,1,CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)(C2CCCCC2)CC1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC(CN=[N+]=[N-])(C2CCCCC2)CC1 -US05674876,6,CC(=O)Oc1c(C)c(C)c2c(c1C)C(C)(C)CN2C(=O)C(C)(C)C>>Cc1c(C)c2c(c(C)c1O)C(C)(C)CN2C(=O)C(C)(C)C -US20030203975A1,1,NCCCCCO.O=C1c2ccccc2C(=O)c2c(Cl)cccc21>>O=C1c2ccccc2C(=O)c2c(NCCCCCO)cccc21 -US20150087699A1,1,C[C@@H](OS(C)(=O)=O)c1oc2cccc(F)c2c(=O)c1-c1cccc(F)c1.[N-]=[N+]=[N-]>>C[C@@H](N=[N+]=[N-])c1oc2cccc(F)c2c(=O)c1-c1cccc(F)c1 -US20120283297A1,1,CCOC(=O)CCCBr.Cc1c(Br)ccc2[nH]ncc12>>CCOC(=O)CCCn1ncc2c(C)c(Br)ccc21 -US20100215632A1,1,CC(C)(C)OC(=O)NC1CCNCC1.O=[N+]([O-])c1ccccc1-c1cn2c(CCl)csc2n1>>CC(C)(C)OC(=O)NC1CCN(Cc2csc3nc(-c4ccccc4[N+](=O)[O-])cn23)CC1 -US20010000513A1,6,COC(=O)CCC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>O=C(O)CCC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US08669249B2,6,COC(=O)c1ccc2c(c1)NC(=O)CO2>>O=C1COc2ccc(C(=O)O)cc2N1 -US06369057B1,7,C[C@H]1C(=O)Nc2c(cc(Cl)cc2[N+](=O)[O-])N1C(=O)OCc1ccccc1>>C[C@H]1C(=O)Nc2c(N)cc(Cl)cc2N1C(=O)OCc1ccccc1 -US04528114,9,CCCCCc1ccc(-c2ccc(CC[C@@H]3CC[C@@H](C=C(Br)Br)CC3)cc2)cc1>>C#C[C@@H]1CC[C@@H](CCc2ccc(-c3ccc(CCCCC)cc3)cc2)CC1 -US04427437,6,COc1ccc(Oc2ncc(Br)cn2)cc1>>Oc1ccc(Oc2ncc(Br)cn2)cc1 -US05135926,1,CC(C)(C)C(=O)OCCl.O=C(O)Cc1ccc(O)cc1>>CC(C)(C)C(=O)OCOC(=O)Cc1ccc(O)cc1 -US20150191439A1,1,NC12CC3CC(CC(C3)C1)C2.O=Cc1c(F)c(F)c(O)c(F)c1F>>Oc1c(F)c(F)c(CNC23CC4CC(CC(C4)C2)C3)c(F)c1F -US20060128790A1,1,CI.Cc1c(C)c2c(c(C)c1O)CC(O)C1(CCC1)O2>>COC1Cc2c(C)c(O)c(C)c(C)c2OC12CCC2 -US05583130,1,CC(C)(C)OC(=O)NCc1ccccc1-c1ccc(CO)cc1.CC(C)(CC(=O)N[C@@H]1CCc2ccccc2NC1=O)NC(=O)OCc1ccccc1>>CC(C)(CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3CNC(=O)OC(C)(C)C)cc2)C1=O)NC(=O)OCc1ccccc1 -US07560558B2,1,COc1cc2c(Oc3cc(C)c(C)nc3-c3cccnc3)ccnc2cc1O.OCCCCBr>>COc1cc2c(Oc3cc(C)c(C)nc3-c3cccnc3)ccnc2cc1OCCCCO -US20080275043A1,6,C[C@@H]1CC2(CC[C@@H]1N1CCC(Cc3ccc(Cl)cc3Cl)C1=O)OCCO2>>C[C@H]1CC(=O)CC[C@H]1N1CCC(Cc2ccc(Cl)cc2Cl)C1=O -US20110217311A1,6,CC(C)(C)OC(=O)N[C@@H]1C[C@@H](Oc2cc(F)ccc2[N+](=O)[O-])C1>>N[C@H]1C[C@H](Oc2cc(F)ccc2[N+](=O)[O-])C1 -US20120197027A1,1,COc1cc2c(Nc3ccc4cc[nH]c4c3)ncnc2cc1O.OCCN1CCCCC1>>COc1cc2c(Nc3ccc4cc[nH]c4c3)ncnc2cc1OCCN1CCCCC1 -US06747027B1,7,COc1ccc(S(=O)(=O)N2CCCC2C(=O)O)cc1>>COc1ccc(S(=O)(=O)N2CCCC2CO)cc1 -US06251938B1,6,CN(CCc1ccccc1)C(=O)OC(C)(C)C>>CNCCc1ccccc1 -US07208598B2,1,CCC(C)n1cnc2c(Cl)nc(Cl)nc21.CCCN>>CCCNc1nc(Cl)nc2c1ncn2C(C)CC -US20150175601A1,1,C=O.O=[N+]([O-])c1ccc(OC2CCNCC2F)cc1>>CN1CCC(Oc2ccc([N+](=O)[O-])cc2)C(F)C1 -US20080269239A1,1,CN1C2CCC1CNC2.Clc1ccc2oc3c(Cl)ncnc3c2c1>>CN1C2CCC1CN(c1ncnc3c1oc1ccc(Cl)cc13)C2 -US03991087,1,C=[N+]=[N-].CCCCCC(O)CCCC(Cl)(CCCCCCC(=O)O)C(C)=O>>CCCCCC(O)CCCC(Cl)(CCCCCCC(=O)OC)C(C)=O -US20100041892A1,1,CCOC(=O)/C=C/c1ccc(OCCOC)cc1O.Cc1cc([N+](=O)[O-])cnc1Cl>>CCOC(=O)/C=C/c1ccc(OCCOC)cc1Oc1ncc([N+](=O)[O-])cc1C -US20080194549A1,1,COC(=O)c1ccc2c(C)c[nH]c2c1.COCCCBr>>COCCCn1cc(C)c2ccc(C(=O)OC)cc21 -US06114390,6,CCOC(=O)Cn1cc(CC(=O)OCc2ccccc2)c2ccccc21>>CCOC(=O)Cn1cc(CC(=O)O)c2ccccc21 -US08486962B2,1,C[O-].O=C(O)c1cc([N+](=O)[O-])ccc1Cl>>COc1ccc([N+](=O)[O-])cc1C(=O)O -US20090082311A1,6,CC(=O)NC(CCc1ccc(-c2cccc3c(OCc4ccccc4)cccc23)cc1)(COC(C)=O)COC(C)=O>>CC(=O)NC(CCc1ccc(-c2cccc3c(O)cccc23)cc1)(COC(C)=O)COC(C)=O -US20140378487A1,1,COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.N#Cc1cncc(Oc2ccc(CO)cc2F)c1>>COc1ccc2c(c1)CCn1c-2cc(OCc2ccc(Oc3cncc(C#N)c3)c(F)c2)nc1=O -US20110230462A1,1,CCCC[Sn](Cl)(CCCC)CCCC.Ic1cc(C2=CCCC2)ccn1>>CCCC[Sn](CCCC)(CCCC)c1cc(C2=CCCC2)ccn1 -US07301036B2,1,COC(=O)c1ccc(Cn2c(=Nc3ccc(O)cc3)n(C)c3cc(Cl)c(Cl)cc32)cc1.OC1CCCC1>>COC(=O)c1ccc(Cn2c(=Nc3ccc(OC4CCCC4)cc3)n(C)c3cc(Cl)c(Cl)cc32)cc1 -US20130116243A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3-c3ccncc3)CO4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3-c3ccncc3)CO4)cc2)CCC1 -US20150225449A1,6,COCCC(=O)N1c2ccccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@@H]1C>>CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)CCOC)[C@H]1C -US07795283B2,6,COC(=O)C1(C)CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(C)CCNCC1 -US20120316147A1,1,CC(C)C[C@H](NC(=O)c1ccc(Br)c(Cl)n1)C(N)=O.Oc1ccc(F)cc1>>CC(C)C[C@H](NC(=O)c1ccc(Br)c(Oc2ccc(F)cc2)n1)C(N)=O -US20150225389A1,7,CC(C)(C)[Si](c1ccccc1)(c1ccccc1)N1C(=O)C[C@H]1C(=O)OCc1ccccc1>>CC(C)(C)[Si](c1ccccc1)(c1ccccc1)N1C(=O)C[C@H]1CO -US20080255083A1,1,O=C(CBr)c1ccc(CO)cc1.O=c1cc(OCc2ccccc2)nc[nH]1>>O=C(Cn1cnc(OCc2ccccc2)cc1=O)c1ccc(CO)cc1 -US20110124633A1,1,CCOC(=O)CNCC(=O)OCC.Nc1ncc(Br)cc1CBr>>CCOC(=O)CN(CC(=O)OCC)Cc1cc(Br)cnc1N -US20130237573A1,1,CC(C)(C)OC(=O)N[C@@]1(C(=O)OC(C)(C)C)[C@H](OCc2ccc(Cl)c(Cl)c2)[C@H](OS(C)(=O)=O)[C@H]2[C@H](C(=O)OC(C)(C)C)[C@H]21.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@@]1(C(=O)OC(C)(C)C)[C@H](OCc2ccc(Cl)c(Cl)c2)[C@@H](N=[N+]=[N-])[C@H]2[C@H](C(=O)OC(C)(C)C)[C@H]21 -US04361563,7,CC1CC(=O)NN=C1c1ccc(NCc2ccccc2)c([N+](=O)[O-])c1>>CC1CC(=O)NN=C1c1ccc(NCc2ccccc2)c(N)c1 -US20140371209A1,1,CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C=O)ccc3c2)CC1.CCOC(=O)C1CCNCC1C>>CCOC(=O)C1CCN(Cc2ccc3cc(O[C@@H]4CC[C@@H](C(C)(C)C)CC4)ccc3c2)CC1C -US04810719,9,COc1ccc(Nc2cc(Cl)n(-c3ccccc3)n2)cc1>>COc1ccc(Nc2ccn(-c3ccccc3)n2)cc1 -US08927536B2,6,Cc1ccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)cn1>>Cc1ccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)cn1 -US07572809B2,1,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.Nc1ccc(F)cc1>>COc1ccc2c(Nc3ccc(F)cc3)nc(Nc3cc(C)[nH]n3)cc2c1 -US05273999,1,BrCCCCCBr.CCOC(=O)CCCCc1ccc(O)c(CCC(=O)OCC)c1>>CCOC(=O)CCCCc1ccc(OCCCCCBr)c(CCC(=O)OCC)c1 -US08263606B2,1,N#Cc1cccc(CBr)c1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCO3>>N#Cc1cccc(CN2C(=O)C3(COc4cc5c(cc43)OCCO5)c3ccccc32)c1 -US05071999,6,C=C(F)CN(CC(OC)OC)C(=O)OCC>>C=C(F)CN(CC=O)C(=O)OCC -US20050054626A1,6,OC1(c2ccccn2)CCC2(CC1)OCCO2>>O=C1CCC(O)(c2ccccn2)CC1 -US20140113882A1,1,CCOC(=O)CBr.O=[N+]([O-])c1ccc(O)cc1>>CCOC(=O)COc1ccc([N+](=O)[O-])cc1 -US05912246,1,ClCc1cn2cc(Cl)ccc2n1.Fc1ccccc1N1CCNCC1>>Fc1ccccc1N1CCN(Cc2cn3cc(Cl)ccc3n2)CC1 -US20020049316A1,10,Cc1cccc(C(=O)O)c1.O=C1CCC(=O)N1Br>>O=C(O)c1cccc(CBr)c1 -US20070197512A1,6,COC(=O)CN1C(=O)COc2c(C(C)C)cccc21>>CC(C)c1cccc2c1OCC(=O)N2CC(=O)O -US20080312209A1,1,OC1CCNC1.Oc1ccc(F)cc1>>Fc1ccc(O[C@@H]2CCNC2)cc1 -US08324223B2,1,Cc1cc(C)c(N)c(C)c1.Clc1nc(Cl)c2sccc2n1>>Cc1cc(C)c(Nc2nc(Cl)nc3ccsc23)c(C)c1 -US07973178B2,1,C[C@H](O)COC(C)(C)C.N#Cc1cc(F)cc(Br)c1>>C[C@@H](COC(C)(C)C)Oc1cc(Br)cc(C#N)c1 -US04182776,6,CCOC(=O)c1ccc(NCCCOc2ccccc2)cc1>>O=C(O)c1ccc(NCCCOc2ccccc2)cc1 -US20100278833A1,6,C[C@H](Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F>>C[C@H](Oc1cc(-n2cnc3cnc(CO)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F -US20090029994A1,1,C1COCCN1.COc1ccc(C(C)C)cc1-c1ccc(OCc2ccccc2)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(Br)cn1>>COc1ccc(C(C)C)cc1-c1ccc(OCc2ccccc2)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(N2CCOCC2)cn1 -US04507296,9,[N-]=[N+]=NCC(O)CCOc1cccc(CN2CCCCC2)c1>>NCC(O)CCOc1cccc(CN2CCCCC2)c1 -US20060135769A1,1,CI.O=C(c1ccc(Cl)cc1)c1ccc2[nH]c(=O)cc(-c3cccs3)c2c1>>Cn1c(=O)cc(-c2cccs2)c2cc(C(=O)c3ccc(Cl)cc3)ccc21 -US05925770,1,CCI.CCOc1ccc(NC(=O)c2c[nH]c3c2C(=O)CCC3)cc1>>CCOc1ccc(NC(=O)c2cn(CC)c3c2C(=O)CCC3)cc1 -US08367831B2,1,NC1CCN(CCn2c(=O)ccc3ccncc32)CC1.O=Cc1nc2c(cc1Cl)SCC(=O)N2>>O=C1CSc2cc(Cl)c(CNC3CCN(CCn4c(=O)ccc5ccncc54)CC3)nc2N1 -US07365076B2,6,CC(C)(C)OC(=O)N1CCN(CC(c2ccc(-c3cccc(C#N)c3)cc2)C2(O)CCCCC2)CC1>>N#Cc1cccc(-c2ccc(C(CN3CCNCC3)C3(O)CCCCC3)cc2)c1 -US06432950B1,1,Cc1sc2nc(-c3ccccn3)nc(Cl)c2c1Cl.NCc1cccc([N+](=O)[O-])c1>>Cc1sc2nc(-c3ccccn3)nc(NCc3cccc([N+](=O)[O-])c3)c2c1Cl -US06011044,1,COc1ccc(N2CCc3c(Cl)nc4c(OC(F)(F)F)cccc4c32)c(C)c1.NCCCO>>COc1ccc(N2CCc3c(NCCCO)nc4c(OC(F)(F)F)cccc4c32)c(C)c1 -US04752645,7,COC(=O)C(C)(C(=O)OC)C(Cc1cc(C(F)(F)F)ccc1[N+](=O)[O-])c1ccc(OC)cc1>>COC(=O)C(C)(C(=O)OC)C(Cc1cc(C(F)(F)F)ccc1N)c1ccc(OC)cc1 -US20100273833A1,6,COCCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)=O)c1>>COCCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(N)c1 -US06329370B1,7,COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C#Cc1ccccc1>>COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C=Cc1ccccc1 -US05116404,1,CI.O=c1cc(-c2cccc(C(F)(F)F)c2)[nH]c(=O)n1-c1ccc(Cl)cc1F>>Cn1c(-c2cccc(C(F)(F)F)c2)cc(=O)n(-c2ccc(Cl)cc2F)c1=O -US07368578B2,1,COC(=O)c1cc(-c2nc(CCl)c(C)o2)ccc1C.COc1cc(C=O)ccc1O>>COC(=O)c1cc(-c2nc(COc3ccc(C=O)cc3OC)c(C)o2)ccc1C -US08314103B2,1,C=CCBr.Cc1nc(-c2ccc(N)cn2)nc(O)c1Cl>>C=CCOc1nc(-c2ccc(N)cn2)nc(C)c1Cl -US20120122842A1,1,C1CCNC1.CC(C)(C)OC(=O)N1Cc2ccc(CO)cc2C1>>CC(C)(C)OC(=O)N1Cc2ccc(CN3CCCC3)cc2C1 -US20080058348A1,7,CC(C)(C)OC(=O)C(CNc1ncnc(N2CCC(c3ccc4c(n3)NCCC4)CC2)c1C=O)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)C(CNc1ncnc(N2CCC(c3ccc4c(n3)NCCC4)CC2)c1CO)NC(=O)OCc1ccccc1 -US07754886B2,1,NS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1.Nc1ccccc1Oc1ccccc1>>NS(=O)(=O)c1ccc(Nc2ccccc2Oc2ccccc2)c([N+](=O)[O-])c1 -US07622605B2,1,CNOC.O=C(Cl)C1CCCC1>>CON(C)C(=O)C1CCCC1 -US06150379,7,N#Cc1cc([N+](=O)[O-])c(N)cc1F>>N#Cc1cc(N)c(N)cc1F -US04051148,6,COC(=O)c1ccc(C(=O)OC)c(SCc2ccccc2)c1>>COC(=O)c1ccc(C(=O)O)cc1SCc1ccccc1 -US06552012B2,1,CCO.Clc1cncc(Cl)c1>>CCOc1cncc(Cl)c1 -US20110092519A1,1,CC(C)(F)C[C@@H](N)CO.C[C@H](Sc1nc(Cl)c2sc(N)nc2n1)c1ccccc1>>C[C@H](Sc1nc(N[C@@H](CO)CC(C)(C)F)c2sc(N)nc2n1)c1ccccc1 -US20040044057A1,1,CON(C)C(=O)CCl.c1c[nH]cn1>>CON(C)C(=O)Cn1ccnc1 -US07414051B2,7,CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c([N+](=O)[O-])c(OCCCl)c2)CC1>>CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c(N)c(OCCCl)c2)CC1 -US05994356,1,O=C(O)COc1ccc(N2CCN(CCC3CCNCC3)CC2)cc1.OC1CCCC1>>O=C(COc1ccc(N2CCN(CCC3CCNCC3)CC2)cc1)OC1CCCC1 -US20140061614A1,1,Brc1cccc(Br)c1.c1ccc2c(c1)[nH]c1ccccc12>>Brc1cccc(-n2c3ccccc3c3ccccc32)c1 -US20070173537A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(F)c(C(F)(F)F)c2)CC1>>Fc1ccc(N2CCNCC2)cc1C(F)(F)F -US08324222B2,9,COC(=O)COc1cccc(Nc2ncnc3oc(-c4ccc(Br)cc4)c(-c4ccc(F)cc4)c23)c1>>COC(=O)COc1cccc(Nc2ncnc3oc(-c4ccccc4)c(-c4ccc(F)cc4)c23)c1 -US20110311459A1,1,CN(c1ccccc1)C(C(=O)O)c1ccccc1.O[C@H]1CN2CCC1CC2>>CN(c1ccccc1)C(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1 -US05342846,1,COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cc1cnnn1C1CCNC1>>COc1c(N2CCC(n3nncc3C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US20010039286A1,1,C1COCCN1.Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCC(O)(Cc3ccccc3)CC2)c2cc(Br)ccc21>>Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCC(O)(Cc3ccccc3)CC2)c2cc(N3CCOCC3)ccc21 -US20150018422A1,6,CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)c(C3CCOCC3)c2)c1)C1CC1>>COc1ccc(F)c(-c2ccc(OCc3cccc(C(CC(=O)O)C4CC4)c3)cc2C2CCOCC2)c1 -US20150266879A1,6,CC(C)[C@H](NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(=O)N1c2ncccc2C[C@H]1C(=O)Nc1ccccc1>>CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1c2ncccc2C[C@H]1C(=O)Nc1ccccc1 -US20060069110A1,1,CN(c1ccnc(F)n1)c1ccnc(Cl)n1.C[C@H](N)Cc1cccc(CNC(=O)OC(C)(C)C)c1>>C[C@@H](Cc1cccc(CNC(=O)OC(C)(C)C)c1)Nc1nccc(N(C)c2ccnc(Cl)n2)n1 -US06875765B2,1,BrCc1ccccc1.O=[N+]([O-])c1ccc(Br)c(O)c1>>O=[N+]([O-])c1ccc(Br)c(OCc2ccccc2)c1 -US20130210803A1,7,Cc1ccc2[nH]cc(-c3ccc(F)cc3)c2c1>>Cc1ccc2c(c1)C(c1ccc(F)cc1)CN2 -US20120100628A1,1,CCCCC(CC)CC1(CC(CC)CCCC)c2cc(Br)ccc2-c2ccc(I)cc21.c1ccc(Nc2ccccc2)cc1>>CCCCC(CC)CC1(CC(CC)CCCC)c2cc(Br)ccc2-c2ccc(N(c3ccccc3)c3ccccc3)cc21 -US06462036B1,7,CCN(CC)CCNC(=O)c1ccc(-c2n[nH]c3c2Cc2ccccc2-3)cc1>>CCN(CC)CCNCc1ccc(-c2n[nH]c3c2Cc2ccccc2-3)cc1 -US20050059723A1,1,Cc1cc2ccccc2[nH]1.Ic1ccc(OCc2ccccc2)cc1>>Cc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1 -US07384432B2,7,COC(=O)CCCCCNc1ccc([N+](=O)[O-])c(C)c1>>COC(=O)CCCCCNc1ccc(N)c(C)c1 -US20110124665A1,1,COC(=O)CCCc1ccccc1N.COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1>>COC(=O)CCCc1ccccc1Nc1ncnc2oc(-c3ccccc3)c(-c3ccc(OC)cc3)c12 -US05189053,4,CC(=O)CC(C)=O.NNc1c(Cl)cc(C(F)(F)F)cc1Cl>>Cc1cc(C)n(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1 -US20150232480A1,9,COC(=O)[C@@H](OC(C)(C)C)c1c(C)c(C=O)c2nc3cn2c1N1CCC(C)(CC1)OCCCC[C@H](C)Oc1ccc(F)c(F)c1-c1cccc-3c1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)c(C=O)c2nc3cn2c1N1CCC(C)(CC1)OCCCC[C@H](C)Oc1ccc(F)cc1-c1cccc-3c1 -US05783605,9,N.O=C(Cl)Cc1ccccc1>>NC(=O)Cc1ccccc1 -US05516904,7,CC(C)CCC(=O)c1ccc(Br)cc1>>CC(C)CCCc1ccc(Br)cc1 -US20040097438A1,6,CCOC(=O)c1ccc2c(c1)nc(-c1ccc(Oc3cccc(OC(C)=O)c3)cc1)n2C1CCCCC1>>CCOC(=O)c1ccc2c(c1)nc(-c1ccc(Oc3cccc(O)c3)cc1)n2C1CCCCC1 -US20070078120A1,4,CCOC(=O)C(Br)CCC(Br)C(=O)OCC.COc1ccccc1N>>CCOC(=O)[C@H]1CC[C@@H](C(=O)OCC)N1c1ccccc1OC -US20040192685A1,6,COc1ccc2c(c1)CCN=C2C1CCN(C(=O)C(F)(F)F)CC1>>COc1ccc2c(c1)CCN=C2C1CCNCC1 -US06211215B1,7,CCOC(=O)c1csc(-c2cccnc2)n1>>OCc1csc(-c2cccnc2)n1 -US20140350244A1,6,O=C(OCC1c2ccccc2-c2ccccc21)N1CCOC2(CCN(Cc3ccccc3)CC2)C1>>O=C(OCC1c2ccccc2-c2ccccc21)N1CCOC2(CCNCC2)C1 -US04085219,6,COc1cc2c(c(Cl)c1Cl)C(=O)C(C)(C(C)C)C2>>CC(C)C1(C)Cc2cc(O)c(Cl)c(Cl)c2C1=O -US05260285,9,CCc1nc2c(C)cc(C)nn2c1C(O)c1ccc(O)cc1>>CCc1nc2c(C)cc(C)nn2c1Cc1ccc(O)cc1 -US20100168418A1,6,CCOC(=O)/C=C/c1cc(OC)cc2c1ccc(=O)n2CCN1CCC(N(Cc2ccc3c(c2)OCCO3)C(=O)OC(C)(C)C)CC1>>CCOC(=O)/C=C/c1cc(OC)cc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1 -US08486967B2,6,CC1(N)CCN(C(=O)OC(C)(C)C)CC1>>CC1(N)CCNCC1 -US20060183909A1,7,COC(=O)c1cc(C#CC(N)C(C)=O)c2cccc([N+](=O)[O-])c2n1>>COC(=O)c1cc(C#CC(N)C(C)=O)c2cccc(N)c2n1 -US05106871,7,COCOc1ccc(C=CC(=O)c2c(OCOC)cc(OCOC)c(CC=C(C)C)c2OC(C)=O)cc1>>COCOc1ccc(CCC(=O)c2c(OCOC)cc(OCOC)c(CC=C(C)C)c2OC(C)=O)cc1 -US20020019569A1,6,CCOC(COCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)OCC>>O=CCOCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl -US20030220402A1,6,COC(=O)c1ccccc1NC(=O)Cc1ccc(Oc2ccc(OCc3ccccc3)cc2)cc1>>O=C(Cc1ccc(Oc2ccc(OCc3ccccc3)cc2)cc1)Nc1ccccc1C(=O)O -US05488140,6,CCOC(=O)C(N)C=C(CCF)CP(=O)(O)O>>NC(C=C(CCF)CP(=O)(O)O)C(=O)O -US07192982B2,7,COC(Cc1cccc(C#CCCCOc2ccc(Oc3ccccc3)cc2)c1)C(=O)O>>COC(Cc1cccc(CCCCCOc2ccc(Oc3ccccc3)cc2)c1)C(=O)O -US20030153611A1,9,COc1ccc(C=C(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1NC(=O)C(N)C(=O)OC(C)(C)C>>COc1ccc(C=C(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1NC(=O)CN -US20120035168A1,7,COC(=O)COc1cc(N)nc(C)c1C#N>>COC(=O)COc1cc(N)nc(C)c1CN -US05319133,9,CCCCCCCCC(C)C(=O)Cl.[NH4+]>>CCCCCCCCC(C)C(N)=O -US08901314B2,7,CC1(C)CC(c2cc(-c3ccc(Cl)cc3)n(-c3ccccc3[N+](=O)[O-])n2)CC(C)(C)O1>>CC1(C)CC(c2cc(-c3ccc(Cl)cc3)n(-c3ccccc3N)n2)CC(C)(C)O1 -US20050070574A1,6,COC(=O)c1c(CN2CCC(NC(=O)OCC3c4ccccc4-c4ccccc43)CC2)c(-c2ccccc2)nc2ccccc12>>O=C(NC1CCN(Cc2c(-c3ccccc3)nc3ccccc3c2C(=O)O)CC1)OCC1c2ccccc2-c2ccccc21 -US20030087952A1,7,CCOC(=O)C1C(c2ccccc2)=CC(=O)N1C>>CCOC(=O)[C@H]1[C@@H](c2ccccc2)CC(=O)N1C -US20130345181A1,6,CCOC(OCC)c1cc2cnc(Br)cc2[nH]1>>O=Cc1cc2cnc(Br)cc2[nH]1 -US20110015181A1,9,Cc1nc(S(=O)(=O)Cl)cn1C>>Cc1nc(S)cn1C -US20120258950A1,9,CC(C)(C)n1cc(C(=O)c2cncc(Br)c2)c2cncnc21.N>>CC(C)(C)n1cc(C(=O)c2cncc(N)c2)c2cncnc21 -US08841289B2,6,COC(=O)c1cc(N2CCN3CCC2CC3)ncc1[N+](=O)[O-]>>O=C(O)c1cc(N2CCN3CCC2CC3)ncc1[N+](=O)[O-] -US04330548,6,O=C1C[C@@H](C(=O)O)N(C(=O)OCc2ccccc2)C1>>O=C1CN[C@H](C(=O)O)C1 -US04071625,7,C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43CO)[C@@H]1CCC2=O>>C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@@H](O)CC[C@@]43CO)[C@@H]1CCC2=O -US06191150B1,7,C=C(C)C[C@@H](C(=O)OC)[C@H](O)CCC>>CCC[C@@H](O)[C@@H](CC(C)C)C(=O)OC -US20050014812A1,6,COc1cccc(-c2cc(C)c3nc(C)n(Cc4ccc(Cl)cc4Cl)c3c2)c1>>Cc1cc(-c2cccc(O)c2)cc2c1nc(C)n2Cc1ccc(Cl)cc1Cl -US20110112065A1,7,CS(=O)(=O)c1ccc(C(=O)O)c(O)c1>>CS(=O)(=O)c1ccc(CO)c(O)c1 -US20150175601A1,7,CC(=O)N1CC[C@H](Oc2ccc([N+](=O)[O-])cc2)C1>>CC(=O)N1CC[C@H](Oc2ccc(N)cc2)C1 -US06881736B1,6,COC(=O)CC(Cc1ccc(OCc2ccccc2)cc1)c1nc(C(F)(F)F)cs1>>COC(=O)CC(Cc1ccc(O)cc1)c1nc(C(F)(F)F)cs1 -US20100022589A1,7,O=C(CSc1ncccc1C(=O)NC1CCCCC1)c1ccccc1>>O=C(NC1CCCCC1)c1cccnc1SCC(O)c1ccccc1 -US08828996B2,6,CC(C)(C)OC(=O)N1CCC2(CC1)CN(Cc1ccccc1)CC(CO)O2>>CC(C)(C)OC(=O)N1CCC2(CC1)CNCC(CO)O2 -US20070066820A1,6,COc1ccc(Cc2ccc(I)cc2)cc1>>Oc1ccc(Cc2ccc(I)cc2)cc1 -US04007276,7,O=[N+]([O-])c1cccc(-c2nc3n(n2)Cc2ccccc2-3)c1>>Nc1cccc(-c2nc3n(n2)Cc2ccccc2-3)c1 -US20110028442A1,6,O=C(NCCCc1ccccc1)Nc1ccc(CCNC[C@H](O)c2ccc(OCc3ccccc3)c3[nH]c(=O)ccc23)cc1>>O=C(NCCCc1ccccc1)Nc1ccc(CCNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1 -US06239130B1,7,Cc1cc2c3n1C(c1ccccc1)=CN(n1c(C)nc4cc(C(=O)O)ccc4c1=O)C(=O)C3=CCC2>>Cc1cc2c3n1C(c1ccccc1)=CN(n1c(C)nc4cc(CO)ccc4c1=O)C(=O)C3=CCC2 -US20090012063A1,7,CCCCCCc1cccc(-c2nc(C#CCO)c(C(=O)N3CCC(N4CCCC4)CC3)n2C)c1>>CCCCCCc1cccc(-c2nc(CCCO)c(C(=O)N3CCC(N4CCCC4)CC3)n2C)c1 -US08415345B2,9,O=S(=O)(Nc1cccc(-c2nc(N3CCOCC3)sc2-c2ccnc(Cl)n2)c1Cl)c1c(F)cccc1F>>O=S(=O)(Nc1cccc(-c2nc(N3CCOCC3)sc2-c2ccncn2)c1Cl)c1c(F)cccc1F -US05910605,9,Cc1c(O)cccc1Cl.N#C[Cu]>>Cc1c(O)cccc1C#N -US20060205769A1,7,CC(C)OC(=O)C[C@@H](c1cc(F)cc(F)c1)C1CCN(S(C)(=O)=O)CC1>>CS(=O)(=O)N1CCC([C@@H](CCO)c2cc(F)cc(F)c2)CC1 -US07067658B2,7,CCC(Nc1nccc(-c2cc(F)c(N(C)C)cc2Cl)c1[N+](=O)[O-])C1CC1>>CCC(Nc1nccc(-c2cc(F)c(N(C)C)cc2Cl)c1N)C1CC1 -US20080221175A1,7,COC(=O)C[C@@H]1CC[C@@H](N(C(=O)c2cccc(F)c2)C2CC2)CC1>>O=C(c1cccc(F)c1)N(C1CC1)[C@@H]1CC[C@@H](CCO)CC1 -US05451677,9,[N-]=[N+]=NCCOc1ccc([N+](=O)[O-])cc1>>NCCOc1ccc([N+](=O)[O-])cc1 -US06432993B1,7,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(Oc3ccccc3)cc2)ccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(Oc3ccccc3)cc2)ccc1N -US05281620,10,Cc1cccc2c(=O)c3ccccc3oc12.O=C1CCC(=O)N1Br>>O=c1c2ccccc2oc2c(CBr)cccc12 -US20150119362A1,4,C[Si](C)(C)N=[N+]=[N-].N#CCc1ccc(Nc2nc(-c3ccc(Cl)s3)nc3c2CCC3)cc1>>Clc1ccc(-c2nc3c(c(Nc4ccc(Cc5nnn[nH]5)cc4)n2)CCC3)s1 -US07851466B2,9,COc1ccc(CCCc2nc(Cl)cc(N3CCOCC3)n2)cc1OC.NN>>COc1ccc(CCCc2nc(NN)cc(N3CCOCC3)n2)cc1OC -US20040157866A1,4,CC(=O)CCC(C)=O.Cc1cccc(N)n1>>Cc1cccc(-n2c(C)ccc2C)n1 -US03931247,7,CC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)o1>>CC(=O)c1ccc(-c2ccc(N)cc2)o1 -US20060142575A1,9,C#CC(O)c1ccc(N2CCN(C)CC2)cc1>>C#CCc1ccc(N2CCN(C)CC2)cc1 -US20050203160A1,7,O=C(O)Cc1cc(-c2ccc(OC(F)(F)F)cc2)nn1CC(F)(F)F>>OCCc1cc(-c2ccc(OC(F)(F)F)cc2)nn1CC(F)(F)F -US20070010455A1,7,O=C1NC(=O)c2ccccc21>>O=C1NCc2ccccc21 -US07833991B2,9,CCCN(CCC)C(C)CCC1Cc2cc(Br)ccc2C1OCOC.[C-]#N>>CCCN(CCC)C(C)CCC1Cc2cc(C#N)ccc2C1OCOC -US20140288044A1,7,O=[N+]([O-])c1ccc(N2CC(O)C2)nc1>>Nc1ccc(N2CC(O)C2)nc1 -US20100210591A1,7,CCOC(=O)/C(C)=C/c1ccc([N+](=O)[O-])cc1>>CCOC(=O)/C(C)=C/c1ccc(N)cc1 -US04705854,9,Clc1ccc2c(c1)Nc1ccccc1S2.N#C[Cu]>>N#Cc1ccc2c(c1)Nc1ccccc1S2 -US06329405B1,7,COc1ccc(C(NC(C)c2cccs2)c2cccc([N+](=O)[O-])c2)cc1>>COc1ccc(C(NC(C)c2cccs2)c2cccc(N)c2)cc1 -US07220863B2,9,Fc1nc(F)c(Cl)c(F)c1F>>Fc1cc(Cl)c(F)nc1F -US07847100B2,9,CC(C)(C)OC(=O)N[C@@](C)(C=O)Cc1ccccc1.NO>>CC(C)(C)OC(=O)N[C@@](C)(C=NO)Cc1ccccc1 -US20150225401A1,7,CC(C)(C)OC(=O)C1(C(=O)O)CC1>>CC(C)(C)OC(=O)C1(CO)CC1 -US20140275015A1,7,COc1ccc(C(C)(O)CN2C=C(C)c3c(nnn3-c3ccc(F)cc3)C2C)cc1>>COc1ccc(C(C)(O)CN2CC(C)c3c(nnn3-c3ccc(F)cc3)C2C)cc1 -US06642231B2,9,COCCCCCN1CCC(=O)CC1.NO>>COCCCCCN1CCC(=NO)CC1 -US20060041128A1,9,Cc1noc2nc(C(N=[N+]=[N-])C(C)C)n(Cc3cccc(F)c3)c(=O)c12>>Cc1noc2nc(C(N)C(C)C)n(Cc3cccc(F)c3)c(=O)c12 -US20070219186A1,9,N.O=C(O)c1cccc(-c2cnn3c(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccnc23)c1>>NC(=O)c1cccc(-c2cnn3c(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccnc23)c1 -US20100069431A1,4,CC(C)Oc1ccc(OCc2ccccc2)cc1C(=O)O.Nc1cccnc1N>>CC(C)Oc1ccc(OCc2ccccc2)cc1-c1nc2cccnc2[nH]1 -US20100278833A1,9,COC(=O)c1sc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)cc1OC(C)c1ccccc1C.N>>Cc1ccccc1C(C)Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O -US20090286768A1,9,Clc1nccn2c(C3CCCCC3)nc(-c3ccc(Oc4ccccc4)cc3)c12.N>>Nc1nccn2c(C3CCCCC3)nc(-c3ccc(Oc4ccccc4)cc3)c12 -US08598341B2,9,Cc1cc(C#N)cc(C)c1Oc1cc(Cl)nc(Nc2ccc(C#N)cc2)n1.N>>Cc1cc(C#N)cc(C)c1Oc1cc(N)nc(Nc2ccc(C#N)cc2)n1 -US07615642B2,9,CCC(C)(C)c1nc2cc(S(=O)(=O)n3cc(C(=O)O)cn3)ccc2n1CC1CCOCC1.N>>CCC(C)(C)c1nc2cc(S(=O)(=O)n3cc(C(N)=O)cn3)ccc2n1CC1CCOCC1 -US05602132,9,Cc1cc(C)c(C#N)c(Cl)n1>>Cc1cc(C)c(C#N)cn1 -US20150175600A1,4,O=C(OCc1ccccc1)N1CC=CCC1.O=C(OO)c1cccc(Cl)c1>>O=C(OCc1ccccc1)N1CCC2OC2C1 -US20100063032A1,9,NC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)nc1N>>N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)nc1N -US20100292279A1,9,COC(=O)c1ccc(C#CC(O)(C2CC2)C2CC2)c(OCCC(F)(F)F)c1>>COC(=O)c1ccc(C#CC(C2CC2)C2CC2)c(OCCC(F)(F)F)c1 -US20120040960A1,9,N.O=C(O)Cc1ccc(C2CCC(N3CC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cc1>>NC(=O)Cc1ccc(C2CCC(N3CC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cc1 -US20150246902A1,9,Clc1ccc(Cl)nn1.NN>>NNc1ccc(Cl)nn1 -US20140275003A1,4,BrCCOCCBr.COc1ncc(N)cc1Br>>COc1ncc(N2CCOCC2)cc1Br -US08518972B2,9,COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CBr)cc3)cccc2C1=O.[N-]=[N+]=[N-]>>COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CN=[N+]=[N-])cc3)cccc2C1=O -US04628123,9,COc1ccc2cc(Br)ccc2c1Br>>COc1ccc2cc(Br)ccc2c1 -US08338361B2,9,CCC(O)CCCCCCC=CCCCCC(=O)O>>CCCCCCCCC/C=C\CCCCC(=O)O -US20150080438A1,9,BrC(Br)(Br)Br.OCCCCCC1=C(c2ccc(O)cc2)CCCc2cc(O)ccc21>>Oc1ccc(C2=C(CCCCCBr)c3ccc(O)cc3CCC2)cc1 -US04054663,9,COC(=O)c1ccnc([N+](=O)[O-])c1.N>>NC(=O)c1ccnc([N+](=O)[O-])c1 -US07928231B2,5,CC(=O)c1ccc2[nH]ccc2c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1 -US20090192322A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)O[C@@H]2CN[C@@H]3[C@@H](O)CO[C@@H]32)cc1>>Cc1ccc(S(=O)(=O)O[C@@H]2CN(C(=O)OC(C)(C)C)[C@@H]3[C@@H](O)CO[C@@H]32)cc1 -US20080146614A1,10,CCOC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OC)cc2)c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OC)cc2)c1CBr -US20120207729A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1cc(-c2cccc([N+](=O)[O-])c2)c2nc(N)sc2c1>>CC(C)(C)OC(=O)Nc1nc2c(-c3cccc([N+](=O)[O-])c3)cc(C#N)cc2s1 -US20070003539A1,5,NCc1ccccc1S(=O)(=O)C1CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCc1ccccc1S(=O)(=O)C1CC1)C(F)(F)F -US20040162442A1,10,C/C=C/C(=O)O[Si](C)(C)C.O=C1CCC(=O)N1Br>>C[Si](C)(C)OC(=O)/C=C/CBr -US20120184531A1,8,CC(C)(C)OC(=O)N1CCc2oc3c(Cl)cc(Sc4ccccc4)cc3c2C1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CCc2oc3c(Cl)cc(S(=O)c4ccccc4)cc3c2C1 -US20150152093A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=Cc1c[nH]cn1>>CC(C)(C)OC(=O)n1cnc(C=O)c1 -US20150223456A1,10,Cc1cnc(Cl)cc1Cl.O=C1CCC(=O)N1Br>>Clc1cc(Cl)c(CBr)cn1 -US20140107094A1,8,COc1nc2ccc(C(O)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1>>COc1nc2ccc(C(=O)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 -US20100004222A1,8,Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)Nc1ccc2sc(C(C)O)nc2c1>>CC(=O)c1nc2cc(NC(=O)c3ccc(/C=C/C(F)(F)F)cc3C)ccc2s1 -US20090253677A1,5,CCOC(=O)C1CCC(=O)CC1.OCCO>>CCOC(=O)C1CCC2(CC1)OCCO2 -US05530017,8,CCCCc1ncc(C(C)O)n1Cc1ccccc1Cl>>CCCCc1ncc(C(C)=O)n1Cc1ccccc1Cl -US20100035917A1,8,CC1(c2cc3cccnc3[nH]2)CC1.O=C(OO)c1cccc(Cl)c1>>CC1(c2cc3ccc[n+]([O-])c3[nH]2)CC1 -US20030078251A1,8,O=[N+]([O-])c1cc(CO)ccc1F>>O=Cc1ccc(F)c([N+](=O)[O-])c1 -US20140148461A1,3,Cc1cccc(C#C[Si](C)(C)C)n1.Cn1nccc1-c1ccc(Br)cc1>>Cc1cccc(C#Cc2ccc(-c3ccnn3C)cc2)n1 -US08217060B2,3,CC1(C)OB(c2ccc(N)c([N+](=O)[O-])c2)OC1(C)C.Fc1cccc(C(F)(F)F)c1Br>>Nc1ccc(-c2c(F)cccc2C(F)(F)F)cc1[N+](=O)[O-] -US08283361B2,3,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(B2OC(C)(C)C(C)(C)O2)cn1.CCOC(=O)c1cn(C(CC)CO)c2ccc(I)cc2c1=O>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(c2)c(=O)c(C(=O)OCC)cn3C(CC)CO)cn1 -US20060030583A1,3,CON(C)C(=O)c1cc(Br)cnc1N.[Mg+]c1ccccc1>>Nc1ncc(Br)cc1C(=O)c1ccccc1 -US08017602B2,3,CC(C)(C)OC(=O)CCOCCc1cccc(Br)c1.COCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COCCn1cc(-c2cccc(CCOCCC(=O)OC(C)(C)C)c2)cn1 -US05110940,3,CCOC(=O)CC(C)=O.CCn1nnnc1C(C=CC=O)=C(c1ccc(F)cc1)c1ccc(F)cc1>>CCOC(=O)CC(=O)CC(O)C=CC(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnnn1CC -US20150057271A1,3,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCCN3c2ccc(C(F)(F)F)cc2Cl)cc1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCCN3c2ccc(C(F)(F)F)cc2-c2ccnn2C)cc1 -US20080176883A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Nc1c(Cl)cccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CC=C(c2cccc([N+](=O)[O-])c2N)CC1 -US20140008617A1,3,Brc1ccccn1.OB(O)c1cccc(Br)c1>>Brc1cccc(-c2ccccn2)c1 -US20150197514A1,3,COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1C.FC(F)(F)Oc1ccc(-n2cnc(Br)n2)cc1>>COC(=O)c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1C -US20140058098A1,3,FC(F)(F)Cn1ncnc1-c1cn2c(n1)-c1cc(Br)ccc1OCC2.OB(O)c1cccnc1F>>Fc1ncccc1-c1ccc2c(c1)-c1nc(-c3ncnn3CC(F)(F)F)cn1CCO2 -US20140275076A1,3,Brc1nnc(-c2ccccc2)s1.CC1(C)OB(c2ccc3c(c2)CC(=O)N3)OC1(C)C>>O=C1Cc2cc(-c3nnc(-c4ccccc4)s3)ccc2N1 -US08501765B2,3,C#C[Si](C)(C)C.Nc1cnc(Br)cc1-c1cc(-c2ccc(CN3CCCCC3)cc2)cnc1F>>C[Si](C)(C)C#Cc1cc(-c2cc(-c3ccc(CN4CCCCC4)cc3)cnc2F)c(N)cn1 -US20100216758A1,3,Fc1cc(I)ccn1.OB(O)c1ccc2ccccc2c1>>Fc1cc(-c2ccc3ccccc3c2)ccn1 -US20110212053A1,10,Cc1ccc(C(C)(C)C#N)cc1.O=C1CCC(=O)N1Br>>CC(C)(C#N)c1ccc(CBr)cc1 -US20120101100A1,3,CCNC(=O)Nc1cc(Cl)c(Br)cn1.CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1cc(Cl)c(-c2cncc(C(=O)OCC)c2)cn1 -US20150246922A1,3,COc1ncc(B(O)O)cn1.Cc1c2n(c3c(Br)cc(F)cc13)CCNC2=O>>COc1ncc(-c2cc(F)cc3c(C)c4n(c23)CCNC4=O)cn1 -US20050096298A1,7,CCOP(=O)(OCC)c1ccc([N+](=O)[O-])cc1>>CCOP(=O)(OCC)c1ccc(N)cc1 -US05827871,7,O=C1c2ccccc2C(=O)N1C1CCc2[nH]c3ccc([N+](=O)[O-])cc3c2C1>>Nc1ccc2[nH]c3c(c2c1)CC(N1C(=O)c2ccccc2C1=O)CC3 -US08143271B2,7,Cc1ccc(S(=O)(=O)n2cc(C(=O)c3cccc([N+](=O)[O-])c3)c3cc(-c4cccnc4)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(C(=O)c3cccc(N)c3)c3cc(-c4cccnc4)cnc32)cc1 -US06451821B1,7,CC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C>>CC(O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C -US07737166B2,7,COC(=O)c1cc(Br)c(F)c([N+](=O)[O-])c1OC>>COC(=O)c1cc(Br)c(F)c(N)c1OC -US04533670,7,O=C(CCn1ccnc1)c1ccc2c(c1)Cc1ccccc1-2>>OC(CCn1ccnc1)c1ccc2c(c1)Cc1ccccc1-2 -US20110110889A1,3,C#CCN(C)C.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3c(c2)cc(I)n3S(=O)(=O)c2ccccc2)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3c(c2)cc(C#CCN(C)C)n3S(=O)(=O)c2ccccc2)c1F -US20140073634A1,10,COC(=O)c1cc(C)ccn1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(CBr)ccn1 -US04590200,7,O=C1C(=Cc2cccnc2)CCc2ccc(Br)cc21>>O=C1c2cc(Br)ccc2CCC1Cc1cccnc1 -US04866086,8,Cc1ccc(C#N)cn1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(C#N)c[n+]1[O-] -US20110130398A1,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12.Nc1cc[nH]c(=O)c1>>CC(C)(C)CC1NC(C(=O)Nc2cc[nH]c(=O)c2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12 -US07495007B2,1,CC1(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Br)ccc23)CC1.NC(=O)CBr>>CC1(C2N(CC(N)=O)C(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Br)ccc23)CC1 -US05691330,1,CC(=O)N1CCc2sc(C)c(C(=O)CCCCl)c2C1.Fc1ccc2c(C3CCNCC3)noc2c1>>CC(=O)N1CCc2sc(C)c(C(=O)CCCN3CCC(c4noc5cc(F)ccc45)CC3)c2C1 -US03988373,1,CC1=CCCC(C)(C)C1/C=C/C(C)N(C)C.ClCc1ccc(Cl)cc1Cl>>CC1=CCCC(C)(C)C1/C=C/C(C)[N+](C)(C)Cc1ccc(Cl)cc1Cl -US20050032873A1,1,COc1cccc2c1CC(NCCCCc1c[nH]c3ccc(F)cc13)CO2.O=C1CCC1>>COc1cccc2c1CC(N(CCCCc1c[nH]c3ccc(F)cc13)C1CCC1)CO2 -US06479531B1,2,CCOC(=O)c1nc(-c2ccccc2)[nH]c1CCC12CC3CC(CC(C3)C1)C2.COC(=O)OCc1cccc(N)c1>>COC(=O)OCc1cccc(NC(=O)c2nc(-c3ccccc3)[nH]c2CCC23CC4CC(CC(C4)C2)C3)c1 -US08153814B2,1,COc1ccc(Cl)cc1-c1ccnc(Cl)c1.OC1CCC1>>COc1ccc(Cl)cc1-c1ccnc(OC2CCC2)c1 -US20090062280A1,1,COC(=O)CN.COc1ccc([N+](=O)[O-])c(Cl)n1>>COC(=O)CNc1nc(OC)ccc1[N+](=O)[O-] -US07632829B2,1,CNC1CCOCC1.O=C(/C=C/c1ccc(Cl)c(Cl)c1)N1CCC(=O)N(CCCCI)CC1>>CN(CCCCN1CCN(C(=O)/C=C/c2ccc(Cl)c(Cl)c2)CCC1=O)C1CCOCC1 -US20050137226A1,1,Ic1ccc(I)cc1.OC1CN2CCC1CC2>>Ic1ccc(OC2CN3CCC2CC3)cc1 -US20130029991A1,2,CC(C)(C)OC(=O)N1CCC(CN)CC1.C[C@H](NC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1)C(=O)O>>C[C@H](NC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1)C(=O)NCC1CCN(C(=O)OC(C)(C)C)CC1 -US20110124633A1,3,C=CC(=O)OC(C)(C)C.CN(C)CCN1Cc2cc(Br)cnc2NC1=O>>CN(C)CCN1Cc2cc(/C=C/C(=O)OC(C)(C)C)cnc2NC1=O -US07618978B2,1,CC[C@H](C)N.COC(=O)c1cc(Cl)nc(C(F)F)c1>>CC[C@H](C)Nc1cc(C(=O)OC)cc(C(F)F)n1 -US06506775B1,1,CC(C)(C)OC(=O)N1CCCC(N)C1c1ccccc1.COc1cc(OC)c(CC(F)(F)F)cc1C=O>>COc1cc(OC)c(CC(F)(F)F)cc1CN[C@H]1CCCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1 -US20150197523A1,2,CC(C)(C)OC(=O)NC(CC(=O)O)Cc1cc(F)c(F)cc1F.FC(F)(F)c1nnc2n1CCNC2>>CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F -US09107916B2,7,O=C1CCc2cc(F)ccc21>>OC1CCc2cc(F)ccc21 -US06110896,1,CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(C)C.COC(=O)CCCI>>CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NCCCC(=O)OC -US07253198B2,7,COC(=O)c1cc(C(=O)O)cc(N2CCCC2=O)c1>>COC(=O)c1cc(CO)cc(N2CCCC2=O)c1 -US20100278835A1,1,NC1CC1.O=[N+]([O-])c1cccc(F)c1CBr>>O=[N+]([O-])c1cccc(F)c1CNC1CC1 -US07064123B1,2,CCCC(N)C(O)c1nnc(CC)o1.O=C(O)C(CC(=O)N1CCOCC1)CC1CCCCC1>>CCCC(NC(=O)C(CC(=O)N1CCOCC1)CC1CCCCC1)C(O)c1nnc(CC)o1 -US07410972B2,2,COc1nc(Cl)cnc1N.Cc1ccc(S(=O)(=O)Cl)s1>>COc1nc(Cl)cnc1NS(=O)(=O)c1ccc(C)s1 -US20120040954A1,4,COc1cc(N)c(C(N)=O)c(OC)c1.O=Cc1ccc2[nH]c(CO)cc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc4[nH]c(CO)cc4c3)nc2c1 -US08546392B2,2,CC(=O)Cl.COc1ccc2cc(-c3ccc(N)c(OC)c3)ccc2c1>>COc1ccc2cc(-c3ccc(NC(C)=O)c(OC)c3)ccc2c1 -US08895313B2,2,COc1c(F)cc(C(=O)O)cc1F.Cc1ccc2nc(-c3ccc(N)cc3)cn2c1>>COc1c(F)cc(C(=O)Nc2ccc(-c3cn4cc(C)ccc4n3)cc2)cc1F -US08314138B2,3,Cc1nc(-c2cnc(Br)cn2)sc1C(=O)NCc1ccccc1.OB(O)/C=C/Cc1ccccc1>>Cc1nc(-c2cnc(/C=C/Cc3ccccc3)cn2)sc1C(=O)NCc1ccccc1 -US08178526B2,1,C1CNCCNC1.FC(F)(F)c1ccc(Cl)nc1>>FC(F)(F)c1ccc(N2CCCNCC2)nc1 -US07560558B2,1,COc1cc2c(Oc3cc(C)c(C)nc3-c3ccc(C)cn3)ccnc2cc1O.OCCBr>>COc1cc2c(Oc3cc(C)c(C)nc3-c3ccc(C)cn3)ccnc2cc1OCCO -US20090170878A1,2,C=CCCCCC(=O)O.C=CCC[C@@H](C)C[C@H](NC(=O)[C@H](C)NC)[C@H](O)CCl>>C=CCCCCC(=O)N(C)[C@@H](C)C(=O)N[C@@H](C[C@H](C)CCC=C)[C@H](O)CCl -US06703392B2,2,CN(C)C(=O)Cl.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NC1CCc3ccccc31)CC2>>COc1ccc(CC2c3cc(OC(=O)N(C)C)c(OC)cc3CCN2CC(=O)NC2CCc3ccccc32)cc1OC -US20110230476A1,2,C=CC(=O)NCC(=O)O.OC1(c2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CCNCC1>>C=CC(=O)NCC(=O)N1CCC(O)(c2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CC1 -US05728706,3,CCCC[Sn](CCCC)(CCCC)c1cccs1.CCCc1nc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c(-c2ccc(C)cc2)c(OCCOc2ncc(Br)cn2)n1>>CCCc1nc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c(-c2ccc(C)cc2)c(OCCOc2ncc(-c3cccs3)cn2)n1 -US08669255B2,1,FC(F)(F)c1cccc(CBr)c1.O=C1NCCN2CC(Oc3cnc(C4CC4)cn3)CC12>>O=C1[C@@H]2C[C@@H](Oc3cnc(C4CC4)cn3)CN2CCN1Cc1cccc(C(F)(F)F)c1 -US20150065482A1,2,CCOC(=O)C(=O)Cl.NCc1ccccn1>>CCOC(=O)C(=O)NCc1ccccn1 -US07691882B2,3,Brc1ccc(Br)nc1.CN(C)C=O>>O=Cc1ccc(Br)nc1 -US20120245161A1,2,COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)C(F)(F)F)ccc3F)CC2)c2c(N)cccc21.O=C(O)C1CC2CCC1C2>>COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)C(F)(F)F)ccc3F)CC2)c2c(NC(=O)C3CC4CCC3C4)cccc21 -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCN(CCCC(O)c3ccc(Cl)cc3)CC2)c1.Oc1ccc(Cl)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCC(Oc3ccc(Cl)cc3)c3ccc(Cl)cc3)CC2)c1 -US05182296,7,COCC1CN(c2ccc3ccc([N+](=O)[O-])cc3c2)C(=O)O1>>COCC1CN(c2ccc3ccc(N)cc3c2)C(=O)O1 -US20100160255A1,3,CC(C)(C)OC(=O)Nc1sc(Br)cc1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1.O=C(OCc1ccccc1)c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)Nc1sc(-c2ccc(C(=O)OCc3ccccc3)cc2)cc1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 -US06627628B1,1,Clc1ccc(-c2nc(Cl)c3c(n2)CCC3)cc1.NC1CCCC1>>Clc1ccc(-c2nc3c(c(NC4CCCC4)n2)CCC3)cc1 -US20110262352A1,1,COC(=O)c1cccnc1N1CCCNCC1.CS(=O)(=O)OC[C@H]1COc2ccccc2O1>>COC(=O)c1cccnc1N1CCCN(C[C@H]2COc3ccccc3O2)CC1 -US03932411,1,BrCCCBr.O=C1CCCc2c(O)cccc21>>O=C1CCCc2c(OCCCBr)cccc21 -US07271266B2,3,CN(C)C=O.O=C(Cc1ccc(Cl)cc1)c1ccccc1Cl>>CN(C)C=C(C(=O)c1ccccc1Cl)c1ccc(Cl)cc1 -US20080039476A1,2,CC(=O)OC(C)=O.NCCc1cccs1>>CC(=O)NCCc1cccs1 -US08927531B2,2,CC(C)OC(=O)Cl.COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C(F)(F)F)c4CN3CCNCC3)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3ccc(C(F)(F)F)c4CN3CCN(C(=O)OC(C)C)CC3)ccc21 -US04012389,1,ClCc1ccc(Cl)c(Cl)c1.O=C1NCCNC1c1ccccc1>>O=C1NCCN(Cc2ccc(Cl)c(Cl)c2)C1c1ccccc1 -US06291505B1,4,COc1ccc(C(=O)CC(=O)c2ccc(OC)cc2)cc1.COc1ccc(NN)cc1>>COc1ccc(-c2cc(-c3ccc(OC)cc3)n(-c3ccc(OC)cc3)n2)cc1 -US04831148,7,O=[N+]([O-])c1cc(Cl)cnc1F>>Nc1cc(Cl)cnc1F -US04389410,8,OCc1cccc(CBr)c1>>O=Cc1cccc(CBr)c1 -US20110082111A1,2,CN1CCC(N)CC1.Cc1cc(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)ccc1C(=O)O>>Cc1cc(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)ccc1C(=O)NC1CCN(C)CC1 -US20060074237A1,3,CC(C)(C)C(=O)Nc1ccc(Br)cn1.CN(C)C=O>>CC(C)(C)C(=O)Nc1ccc(C=O)cn1 -US04931453,2,CCOC(=O)c1nnc(-c2ccccc2)cc1-c1cccc([N+](=O)[O-])c1.CN(C)CCN>>CN(C)CCNC(=O)c1nnc(-c2ccccc2)cc1-c1cccc([N+](=O)[O-])c1 -US20080015203A1,1,CCOC(=O)c1ccc(F)cc1.Cc1cnc(NC(=O)c2cc(O)cc(O[C@@H](C)CO)c2)cn1>>CCOC(=O)c1ccc(Oc2cc(O[C@@H](C)CO)cc(C(=O)Nc3cnc(C)cn3)c2)cc1 -US06867218B2,7,CCOC(=O)/C=C(\C)c1ccc(-c2ccc(Br)cc2)cc1>>C/C(=C\CO)c1ccc(-c2ccc(Br)cc2)cc1 -US06087390,1,CC(C)C1=CC2CC3(C=O)C4CCC(C)C4CC2(COC24OC5C(O)C(OC5(O[SiH](C)C)O2)C4C(C)(C)C)C13C(=O)OC(c1ccccc1)c1ccccc1.CCCCCCCCCCBr>>CCCCCCCCCCOC1C2OC3(O[SiH](C)C)OC(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)OC(c4ccccc4)c4ccccc4)(OC13)C2C(C)(C)C -US07943634B2,1,CCOC(=O)N1CCc2c(oc3c(OC)ccc(C(=O)O)c23)C1.O=[N+]([O-])c1ccc(O)cc1>>CCOC(=O)N1CCc2c(oc3c(OC)ccc(C(=O)Oc4ccc([N+](=O)[O-])cc4)c23)C1 -US08163740B2,1,CC1(C)Cc2cccc(NC3=Nc4ccc(N)cc4CO3)c2O1.O=Cc1ncc[nH]1>>CC1(C)Cc2cccc(NC3=Nc4ccc(NCc5ncc[nH]5)cc4CO3)c2O1 -US20050143382A1,1,Cc1[nH]c2ccccc2c1C=O.NNc1nc2nonc2nc1Nc1ccc(F)c(Cl)c1>>Cc1[nH]c2ccccc2c1C=NNc1nc2nonc2nc1Nc1ccc(F)c(Cl)c1 -US20110124642A1,2,Nn1nc(C2CCCCC2)c2ccccc2c1=O.O=C(Cl)CC12CC3CC(CC(C3)C1)C2>>O=C(CC12CC3CC(CC(C3)C1)C2)Nn1nc(C2CCCCC2)c2ccccc2c1=O -US20120121540A1,2,CNCc1cccs1.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl>>CN(Cc1cccs1)C(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl -US06686389B2,2,CC(C)(C)C(=O)Cl.COc1ccc(O)c(C(C)(C)C)c1>>COc1ccc(OC(=O)C(C)(C)C)c(C(C)(C)C)c1 -US20080039459A1,1,ClCc1cccnc1.OCc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>Clc1nc(N2CCOCC2)c2sc(COCc3cccnc3)cc2n1 -US05856529,7,CCOC(=O)c1cccc(O)c1CCCC(=O)O>>CCOC(=O)c1cccc(O)c1CCCCO -US06159983,2,Cc1ccc(O)cc1.O=C(Cl)CCCl>>Cc1ccc(OC(=O)CCCl)cc1 -US20110039852A1,2,CCNCc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OCC)ccc1OC.O=C(Cl)C1(c2ccc(Cl)cc2Cl)CC1>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)C2(c3ccc(Cl)cc3Cl)CC2)c1 -US20120077814A1,3,CC(C)(C)Sc1ncnc2c(Br)csc12.CC1(C)OB(C2=CC(=O)CC2)OC1(C)C>>CC(C)(C)Sc1ncnc2c(C3=CC(=O)CC3)csc12 -US20030225064A1,3,Cc1nc(-c2ccc(Br)cc2)c(-c2ccc(S(C)(=O)=O)cc2)o1.OB(O)c1cccs1>>Cc1nc(-c2ccc(-c3cccs3)cc2)c(-c2ccc(S(C)(=O)=O)cc2)o1 -US04604389,8,COc1cc2c(cc1OC)CC(=O)N(CCCN(C)CCSc1ccccc1)CC2.OO>>COc1cc2c(cc1OC)CC(=O)N(CCCN(C)CCS(=O)c1ccccc1)CC2 -US20120022056A1,1,C=CCc1cccc([N+](=O)[O-])c1O.CC#CCBr>>C=CCc1cccc([N+](=O)[O-])c1OCC#CC -US08202881B2,2,CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(N)nc21.O=C(N=C=S)c1ccccc1>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(=S)NC(=O)c3ccccc3)nc21 -US07576213B2,2,CC(Cl)C(=O)Cl.Oc1coccc1=S>>CC(Cl)C(=O)Oc1coccc1=S -US07053086B2,3,CCOC(=O)c1c(C)[nH]c(C=O)c1CCCN1CCN(C)CC1.Nc1ccc(-c2cccc3c2CC(=O)N3)cn1>>CCOC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3cccc(-c4ccc(N)nc4)c32)c1CCCN1CCN(C)CC1 -US20080064691A1,1,C1CSCCN1.CS(=O)(=O)OC[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1>>O=C(N[C@@H]1Cc2ccccc2[C@H]1CN1CCSCC1)c1cc2cc(Cl)sc2[nH]1 -US04031226,2,CC(=O)OC(C)=O.Nc1cc(F)ccc1C(=O)NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1>>CC(=O)Nc1cc(F)ccc1C(=O)NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1 -US20130045169A1,7,O=C(OCc1ccccc1)c1cc(Br)cc(OCCCCCCCCC2OCCO2)c1>>OCc1cc(Br)cc(OCCCCCCCCC2OCCO2)c1 -US07932245B2,2,NCC(N)=O.O=C(O)C1CC12CCCCC2>>NC(=O)CNC(=O)C1CC12CCCCC2 -US20130030012A1,1,CC(C)N1CCCn2c1cc(Cl)nc2=O.OCc1ccc(Oc2ccc(C(F)(F)F)nc2)c(F)c1>>CC(C)N1CCCn2c1cc(OCc1ccc(Oc3ccc(C(F)(F)F)nc3)c(F)c1)nc2=O -US07999006B2,1,C[C@H]1NC(=O)OC12CNC2.O=Cc1ccccc1>>C[C@H]1NC(=O)OC12CN(Cc1ccccc1)C2 -US20140155385A1,2,Nc1nccn2c([C@@H]3CCCN3)nc(-c3ccc(C(=O)Nc4ccccn4)cc3)c12.O=C(O)C#CC1CC1>>Nc1nccn2c([C@@H]3CCCN3C(=O)C#CC3CC3)nc(-c3ccc(C(=O)Nc4ccccn4)cc3)c12 -US20060116368A1,2,Nc1cnc2ccccc2n1.O=C(O)C1CCN(c2cnc3ccccc3c2)CC1>>O=C(Nc1cnc2ccccc2n1)C1CCN(c2cnc3ccccc3c2)CC1 -US07435735B2,1,BrCc1ccccc1.CCOC(=O)c1cn2c(c1O)C(=O)N(C)CC2>>CCOC(=O)c1cn2c(c1OCc1ccccc1)C(=O)N(C)CC2 -US20090221645A1,3,C=CCBr.Clc1ccc2cccc(C3=C(Br)SC4=NCCN43)c2c1>>C=CCC1=C(c2cccc3ccc(Cl)cc23)N2CCN=C2S1 -US20030195219A1,2,CCCN(CCc1cccc(N)c1)CCN1CCN(c2ccccc2)CC1.O=S(=O)(Cl)c1ccc(Cl)cc1>>CCCN(CCc1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1)CCN1CCN(c2ccccc2)CC1 -US20050250822A1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.Cc1cc(C(=O)c2ccc(Cl)cc2)ccc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>C=C(c1ccc(Cl)cc1)c1ccc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)c1 -US06498172B1,1,CC(C)(C)OC(=O)COc1cccc(CN)c1.O=Cc1ccc(-c2ccccn2)cc1>>CC(C)(C)OC(=O)COc1cccc(CNCc2ccc(-c3ccccn3)cc2)c1 -US20090181967A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC[C@@H]1CNCCO1>>CC(C)(C)OC(=O)N1CCO[C@H](CO)C1 -US20130158075A1,2,CC(=O)NC(=O)CC1CCC(c2ncc(-c3ccc(N)cc3)s2)CC1.O=C(Cl)c1c(F)cccc1F>>CC(=O)NC(=O)CC1CCC(c2ncc(-c3ccc(NC(=O)c4c(F)cccc4F)cc3)s2)CC1 -US20080319043A1,7,CC(=O)NC1C2CN(Cc3ccccc3)CC21>>CCNC1C2CN(Cc3ccccc3)CC21 -US06380387B1,1,CCN(CC)CCCl.Cc1cccc(Cl)c1C(=O)N[C@@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)C(=O)O>>CCN(CC)CCOC(=O)[C@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)NC(=O)c1c(C)cccc1Cl -US20100125064A1,1,N#CCBr.c1cc(C2CCNCC2)ccn1>>N#CCN1CCC(c2ccncc2)CC1 -US20130029942A1,7,COc1ccc(N(C)c2nc(C)nc3ccc([N+](=O)[O-])cc23)c(F)c1>>COc1ccc(N(C)c2nc(C)nc3ccc(N)cc23)c(F)c1 -US20070169814A1,7,O=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1>>OCc1ccc(N(c2ccccc2)c2ccccc2)cc1 -US20070254877A1,3,C#Cc1ccccc1.CC(C)(C)OC(=O)N1CCC(=O)CC1>>CC(C)(C)OC(=O)N1CCC(O)(C#Cc2ccccc2)CC1 -US20090215829A1,3,Brc1ccccc1OCCN1Cc2ccccc2C1.NC(=O)Nc1cc(Br)sc1C(N)=O>>NC(=O)Nc1cc(-c2ccccc2OCCN2Cc3ccccc3C2)sc1C(N)=O -US07655641B2,7,O=[N+]([O-])c1ccc(C(F)(F)F)c(Cl)c1>>Nc1ccc(C(F)(F)F)c(Cl)c1 -US20120190680A1,1,Clc1ncccn1.O=C(c1c[nH]c2cccc(Cl)c12)C(F)(F)F>>O=C(c1cn(-c2ncccn2)c2cccc(Cl)c12)C(F)(F)F -US20140212384A1,1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3ccc([N+](=O)[O-])c(Cl)c3)S(C)(=O)=O)c(C3CC3)cc12.C[S-]>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3ccc([N+](=O)[O-])c(SC)c3)S(C)(=O)=O)c(C3CC3)cc12 -US20100249123A1,7,CC(C)(C#N)c1ccc([N+](=O)[O-])cc1Br>>CC(C)(C#N)c1ccc(N)cc1Br -US04025630,1,CCCCCc1cc(O)c2c(c1)OC(C)(C)C1CCC(C)=CC21.O=C(O)CCCN1CCOCC1>>CCCCCc1cc(OC(=O)CCCN2CCOCC2)c2c(c1)OC(C)(C)C1CCC(C)=CC21 -US20080234349A1,2,O=Cc1ccc2[nH]ccc2c1.O=S(=O)(Cl)c1ccc(Br)s1>>O=Cc1ccc2c(ccn2S(=O)(=O)c2ccc(Br)s2)c1 -US07427631B2,3,CC(C)(C)OC(=O)N1CCC(I)CC1.Clc1ccc(Br)nc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cn2)CC1 -US20090325987A1,7,C=CCc1cccc([N+](=O)[O-])c1C(=O)OC>>C=CCc1cccc(N)c1C(=O)OC -US20100210630A1,1,COC(=O)CCCBr.c1ccc(COc2ccc(CN3CCCNCC3)cc2)cc1>>COC(=O)CCCN1CCCN(Cc2ccc(OCc3ccccc3)cc2)CC1 -US06365736B1,7,CCC(=O)c1ccc2c(c1)NC(=O)C(C)O2>>CCC(O)c1ccc2c(c1)NC(=O)C(C)O2 -US08664220B2,1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4N)cc3)cc2)CC1.Clc1cccc(-c2cncc(Br)c2)c1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cncc(-c5cccc(Cl)c5)c4)cc3)cc2)CC1 -US20080234384A1,1,O=C(O)c1cc(F)ccc1S.O=C(O)c1ccsc1Br>>O=C(O)c1cc(F)ccc1Sc1sccc1C(=O)O -US05428038,1,COc1cc2oc(=O)c3c(c2cc1OCCCCl)CCC3.COc1ccccc1N1CCNCC1>>COc1cc2oc(=O)c3c(c2cc1OCCCN1CCN(c2ccccc2OC)CC1)CCC3 -US20090156578A1,1,ClCc1cccnc1.Nc1ncc(Br)cc1O>>Nc1ncc(Br)cc1OCc1cccnc1 -US06274705B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccccc1>>CC(C)(C)OC(=O)NCCc1ccccc1 -US20070265268A1,3,CN(C)C=O.COCOc1cc(COCc2ccccc2)c(Br)c(OCOC)c1>>COCOc1cc(COCc2ccccc2)c(C=O)c(OCOC)c1 -US20120270864A1,2,CC(C)(C)OC(=O)NC1CCN(CCO)CC1F.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC1CCN(CCOS(C)(=O)=O)CC1F -US08710224B2,2,C1CNCCN1.CCN1CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)O)C1>>CCN1CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)N2CCNCC2)C1 -US07501541B2,2,COc1ccc(NCCc2ccc(C(F)(F)F)cc2)cc1OC.O=C(O)C(C(=O)OCc1ccccc1)c1ccccc1>>COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)C(C(=O)OCc2ccccc2)c2ccccc2)cc1OC -US20090060838A1,7,COc1ccc([N+](=O)[O-])cc1NS(C)(=O)=O>>COc1ccc(N)cc1NS(C)(=O)=O -US20110280812A1,2,C#CC#CCC/C=C/C=C/C(=O)O.CC(C)CN>>C#CC#CCC/C=C/C=C/C(=O)NCC(C)C -US05286738,1,CNC(=O)n1nc(C(C)(C)C)nc1O.ClCc1ccccc1>>CNC(=O)n1nc(C(C)(C)C)nc1OCc1ccccc1 -US20080318779A1,3,CC(C)Br.COc1ccc(C=O)cc1OC>>COc1ccc(C(O)C(C)C)cc1OC -US20120101123A1,3,CC(C)Oc1ccc(-c2nnc(Br)s2)cc1Cl.CCOC(=O)CCn1ccc2c(B3OC(C)(C)C(C)(C)O3)ccnc21>>CCOC(=O)CCn1ccc2c(-c3nnc(-c4ccc(OC(C)C)c(Cl)c4)s3)ccnc21 -US03950339,1,Cc1cc(Cl)nc(SCC#N)n1.NCc1ccc(Cl)cc1>>Cc1cc(NCc2ccc(Cl)cc2)nc(SCC#N)n1 -US08222260B2,1,COc1cccc(N)c1.Clc1nc(Cl)c2[nH]cnc2n1>>COc1cccc(Nc2nc(Cl)nc3nc[nH]c23)c1 -US08673906B2,1,CC(Br)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12.COc1ccc(C#N)cc1N>>COc1ccc(C#N)cc1NC(C)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 -US04386100,2,O=C(Cl)OCc1ccccc1.O=C1NC(=O)C2(N1)C(=O)N(Cc1ccc(Cl)c(Cl)c1)c1ccccc12>>O=C1NC(=O)C2(C(=O)N(Cc3ccc(Cl)c(Cl)c3)c3ccccc32)N1C(=O)OCc1ccccc1 -US08933105B2,8,CCC(O)c1cccnc1F>>CCC(=O)c1cccnc1F -US20110263571A1,3,CB(O)O.Cc1cc(Br)cnc1N1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)c(C)c1 -US20090247766A1,2,N#Cc1ccccc1N.O=C(Cl)c1ccccc1>>N#Cc1ccccc1NC(=O)c1ccccc1 -US09156823B2,3,CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2ccc3c(c2)C(F)(F)c2cc(Br)ccc2-3)[nH]1.COC(=O)N[C@H](C(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1c1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1c1nc2ccc(-c3ccc4c(c3)C(F)(F)c3cc(-c5cnc([C@@H]6CCCN6C(=O)OC(C)(C)C)[nH]5)ccc3-4)cc2[nH]1)C(C)C -US20080292561A1,1,Cc1nc(N)c2cn[nH]c2n1.Fc1ccccc1I>>Cc1nc(N)c2cnn(-c3ccccc3F)c2n1 -US08486953B2,7,CCOc1cc(C(N)=O)ccc1[N+](=O)[O-]>>CCOc1cc(C(N)=O)ccc1N -US20080153857A1,1,COCc1nc(Cl)c2ccc(-c3ncccc3Cl)nc2n1.Nc1ccc(C(F)(F)F)cc1>>COCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3Cl)nc2n1 -US06015825,7,C=C(c1ccc(-c2ccnn2C)cc1)[C@](O)(Cn1cncn1)c1ccc(F)cc1F>>C[C@@H](c1ccc(-c2ccnn2C)cc1)[C@](O)(Cn1cncn1)c1ccc(F)cc1F -US06982348B2,1,Cc1cccc(O)c1.FC(F)(F)CI>>Cc1cccc(OCC(F)(F)F)c1 -US06180677B2,2,CC(C)(C)NC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1.O=C(O)C1(c2ccccc2)CCCC1>>CC(C)(C)NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)C1(c2ccccc2)CCCC1 -US07019147B1,1,Brc1cccc2ccc(-n3cnc4cc5c(cc43)OCCO5)nc12.CC(C)(C)OC(=O)NC1CCNCC1>>CC(C)(C)OC(=O)NC1CCN(c2cccc3ccc(-n4cnc5cc6c(cc54)OCCO6)nc23)CC1 -US08716491B2,1,CI.Cc1nc2cc(Cl)c(Cl)cc2[nH]1>>Cc1nc2cc(Cl)c(Cl)cc2n1C -US07582761B2,1,C[C@H]1CNCCN1.Clc1ncccc1Br>>C[C@H]1CN(c2ncccc2Br)CCN1 -US20140080763A1,1,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](CSCc1ccccc1)Cc1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C.O=CCCC(=O)O>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](CSCc1ccccc1)Cc1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)O)C(C)C -US20020156081A1,7,Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@@H]1C[C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)C1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@H]1C[C@H](O)C1 -US20100120793A1,2,CCOC(=O)C1(COc2ccc(-c3ccc(F)cc3)cc2)CCNC1.O=C=Nc1ccccc1Cl>>CCOC(=O)C1(COc2ccc(-c3ccc(F)cc3)cc2)CCN(C(=O)Nc2ccccc2Cl)C1 -US08552031B2,2,CC(=NN)c1csc(-c2ccc(Cl)c(Cl)c2)c1O.COC(=O)CN=C=S>>COC(=O)CNC(=S)NN=C(C)c1csc(-c2ccc(Cl)c(Cl)c2)c1O -US20140275030A1,3,Cc1noc(C)c1B(O)O.O=c1[nH]c2ccc(Br)c3c2n1C(C1CCCCN1)CO3>>Cc1noc(C)c1-c1ccc2[nH]c(=O)n3c2c1OCC3C1CCCCN1 -US20080132477A1,1,C=CCOc1cc(CO)cc(C(=O)OC)c1.CI>>C=CCOc1cc(COC)cc(C(=O)OC)c1 -US07119122B2,1,CN.N#Cc1ccc(Cl)cc1Oc1cccc(C=O)c1OCCF>>CNCc1cccc(Oc2cc(Cl)ccc2C#N)c1OCCF -US07332487B2,1,CC(C)(C)OC(=O)NC1CCC(=O)CC1.CNCc1ccccc1>>CN(Cc1ccccc1)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1 -US20070066628A1,7,N#Cc1cccc(-c2ccc3c(c2)CCC3=O)c1>>N#Cc1cccc(-c2ccc3c(c2)CCC3O)c1 -US07572809B2,1,COc1ccccc1O.Cc1cc(Nc2cc3ccccc3c(Cl)n2)n[nH]1>>COc1ccccc1Oc1nc(Nc2cc(C)[nH]n2)cc2ccccc12 -US06596719B1,2,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(C)nc1OCCN.O=S(=O)(Cl)c1ccccc1>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(C)nc1OCCNS(=O)(=O)c1ccccc1 -US05877317,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Oc1ccc(N2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(O)cc2)CC1 -US05719143,2,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.COc1cc(C)cc(OC)c1C1=NC(N)C(=O)N(C)c2ccccc21>>COc1cc(C)cc(OC)c1C1=NC(NC(=O)C(Cc2ccccc2)NC(=O)OC(C)(C)C)C(=O)N(C)c2ccccc21 -US07776847B2,1,C[S-].O=Cc1c(Cl)cccc1Cl>>CSc1cccc(Cl)c1C=O -US04061672,1,O=C(O)CCCCCCC1=CC(Br)CC1=O.OCCO>>O=C(O)CCCCCCC1=CC(OCCO)CC1=O -US20110060107A1,2,C#CCO.CC(C)(Br)C(=O)O>>C#CCOC(=O)C(C)(C)Br -US06329392B1,1,COc1cc(C(=O)N2CCC(CCN3CCC(C(=O)c4nc5ccccc5[nH]4)CC3)(c3ccccc3)C2)cc(OC)c1OC.OCc1ccc(CO)o1>>COc1cc(C(=O)N2CCC(CCN3CCC(C(=O)c4nc5ccccc5n4Cc4ccc(CO)o4)CC3)(c3ccccc3)C2)cc(OC)c1OC -US20100261702A1,2,N#Cc1ccc(S(=O)(=O)Cl)cc1.NCCO>>N#Cc1ccc(S(=O)(=O)NCCO)cc1 -US20090197859A1,1,CN1CCNCC1.N#Cc1cccc(Cl)n1>>CN1CCN(c2cccc(C#N)n2)CC1 -US06489322B1,1,C=O.O=[N+]([O-])c1ccc2c(c1)CNCCO2>>CN1CCOc2ccc([N+](=O)[O-])cc2C1 -US20140112945A1,2,CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)O.COc1ccc(C2=NN(C3CCNCC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](NC(=O)OC(C)(C)C)C(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US20110172204A1,1,COC(=O)c1cnc(Cl)nc1.COC1CNC1>>COC(=O)c1cnc(N2CC(OC)C2)nc1 -US20150152047A1,2,CC(C)(C)OC(=O)N1CCC(Cc2c(Cl)cc(C(=O)O)cc2C(F)(F)F)CC1.CCS(=O)(=O)c1ccc(Cl)cc1CN>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CC2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)c1 -US07625902B2,1,BrCc1ccccc1.Cc1ccc(C)c(N2CCN(C(=O)[C@@H]3CN(S(=O)(=O)c4ccccc4)C(=O)N3)CC2)c1>>Cc1ccc(C)c(N2CCN(C(=O)[C@@H]3CN(S(=O)(=O)c4ccccc4)C(=O)N3Cc3ccccc3)CC2)c1 -US20150259291A1,1,Cc1ccc(CN)cc1.O=C1CCN(C(=O)C(F)(F)F)CC1>>Cc1ccc(CNC2CCN(C(=O)C(F)(F)F)CC2)cc1 -US20040092510A1,7,CC(=O)N1N=C(c2ccc([N+](=O)[O-])c(Cl)c2)c2cc(Cl)ccc2CC1C>>CC(=O)N1N=C(c2ccc(N)c(Cl)c2)c2cc(Cl)ccc2CC1C -US04260775,1,CCOC(=O)c1c[nH]nc1N.O=Cc1ccccc1>>CCOC(=O)c1c[nH]nc1NCc1ccccc1 -US07812017B2,2,COc1ccc2[nH]ccc2c1CN(C)C.O=S(=O)(Cl)c1ccc(F)c(C(F)(F)F)c1>>COc1ccc2c(ccn2S(=O)(=O)c2ccc(F)c(C(F)(F)F)c2)c1CN(C)C -US20050131014A1,1,Cc1ccccc1CBr.O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(O)c1>>Cc1ccccc1COc1cccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 -US05663346,3,O=C1Cc2cc(S(=O)(=O)O)ccc2N1.O=Cc1c[nH]c2ncccc12>>O=C1Nc2ccc(S(=O)(=O)O)cc2C1=Cc1c[nH]c2ncccc12 -US20130096113A1,7,CSc1nc2c(F)cc(CNc3ncccc3[N+](=O)[O-])c(F)c2s1>>CSc1nc2c(F)cc(CNc3ncccc3N)c(F)c2s1 -US04399131,4,CCCON=C(C(=O)CBr)C(=O)OCC.NC(N)=S>>CCCON=C(C(=O)OCC)c1csc(N)n1 -US20090029976A1,2,CC(C)N1CCC(Oc2ccc3oc(C(=O)O)cc3c2)CC1.O=S1(=O)CCNCC1>>CC(C)N1CCC(Oc2ccc3oc(C(=O)N4CCS(=O)(=O)CC4)cc3c2)CC1 -US07173023B2,2,CC(=O)[O-].O=C1Cc2ccc(OCc3cccc(Cl)c3)cc2CCN1>>CC(=O)N1CCc2cc(OCc3cccc(Cl)c3)ccc2CC1=O -US05614544,3,Cc1oc(-c2ccccc2)nc1CCC(=O)c1ccc(C=O)cc1.c1ccc([P+](CC2OCCO2)(c2ccccc2)c2ccccc2)cc1>>Cc1oc(-c2ccccc2)nc1CCC(=O)c1ccc(C=CC2OCCO2)cc1 -US20080153799A1,1,CCc1c(CO)cccc1Nc1c(C(N)=O)cnc2cc(O)c(OC)cc12.COCCBr>>CCc1c(CO)cccc1Nc1c(C(N)=O)cnc2cc(OCCOC)c(OC)cc12 -US20050176775A1,6,COC(=O)c1ccc(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)o1>>Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1ccc(C(=O)O)o1 -US20140142083A1,6,CCN(c1cncc(C(=O)OC)c1C)C1CCOCC1>>CCN(c1cncc(C(=O)O)c1C)C1CCOCC1 -US05824690,6,CCOc1c(OC)cc(C(=O)OC)cc1OC>>CCOc1c(OC)cc(C(=O)O)cc1OC -US20110201581A1,1,C[S-].N#Cc1cc(I)ccc1F>>CSc1ccc(I)cc1C#N -US20050165026A1,2,Nc1c(C(F)(F)F)cc(OCc2ccccc2)cc1C(F)(F)F.O=C(Br)CBr>>O=C(CBr)Nc1c(C(F)(F)F)cc(OCc2ccccc2)cc1C(F)(F)F -US20150175539A1,6,Cc1cc(OCc2ccccc2)cc2[nH]c(C(=O)NC3CCCCC3)cc12>>Cc1cc(O)cc2[nH]c(C(=O)NC3CCCCC3)cc12 -US07166621B2,6,CCC(Oc1cncc(Cl)c1)C(=O)OC>>CCC(Oc1cncc(Cl)c1)C(=O)O -US05739338,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)N(c2ccc(C)cc2)CCC3(C)C)cc1F>>Cc1ccc(N2CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)c(F)c4)cc32)cc1 -US08440651B2,1,CC(C)(O)C1CCN(Cc2ccc3nc(Cl)nc(N4CCOCC4)c3n2)CC1.CC(C)c1nc2ccccc2[nH]1>>CC(C)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)ccc2n1 -US20080181866A1,2,Nc1nc(-c2ccc(C(=O)NC3CC3)cc2)cs1.O=C(O)C1CS[C@H](c2ccccc2)N1C(=O)OCc1ccccc1>>O=C(NC1CC1)c1ccc(-c2csc(NC(=O)C3CS[C@H](c4ccccc4)N3C(=O)OCc3ccccc3)n2)cc1 -US04659735,6,CCOC(=O)c1ccc(C=C(C)c2cc3c(s2)C(C)(C)CCC3(C)C)cc1>>C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(s1)C(C)(C)CCC2(C)C -US05614548,1,CCCCCCCCCCCCCCCCSCC(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1.CI>>CCCCCCCCCCCCCCCCSCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)OC -US07494997B2,2,CN(C)Cc1ccc(C(=O)Cl)cc1Br.Cc1ccc(N)cc1Nc1nccc(-c2cccnc2)n1>>Cc1ccc(NC(=O)c2ccc(CN(C)C)c(Br)c2)cc1Nc1nccc(-c2cccnc2)n1 -US20150031674A1,6,Cc1nccnc1-c1ccc(NC(=O)OC(C)(C)C)c(Cl)c1>>Cc1nccnc1-c1ccc(N)c(Cl)c1 -US20100278733A1,1,CC(=O)c1ccc(O)cc1.OCCCl>>CC(=O)c1ccc(OCCO)cc1 -US06121448,1,CCCCCC[C@@H](F)CO.Oc1ncccn1>>CCCCCCC(F)COc1ncccn1 -US08906889B2,3,C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC1(C)OB(C2=CCC(O)(C(=O)OCc3ccccc3)CC2)OC1(C)C>>C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(O)(C(=O)OCc7ccccc7)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20040110802A1,6,N#Cc1ccc(NC(=O)c2nc3ccccc3o2)c(C(=O)OCc2ccccc2)c1>>N#Cc1ccc(NC(=O)c2nc3ccccc3o2)c(C(=O)O)c1 -US20150057265A1,6,COC(=O)c1sc2cc(OC)cnc2c1Br>>COc1cnc2c(Br)c(C(=O)O)sc2c1 -US20020019569A1,1,CCOC(COCCCCO)OCC.Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>CCOC(COCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)OCC -US20140094474A1,2,C[C@H](N)Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1.Cn1cc(C(=O)O)nc1C1CC1>>C[C@@H](Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1)NC(=O)c1cn(C)c(C2CC2)n1 -US20150284395A1,6,CCOC(=O)c1ccc(F)c(OCC)c1>>CCOc1cc(C(=O)O)ccc1F -US20120142706A1,1,Clc1cnc(Cl)cn1.c1nc[nH]n1>>Clc1cnc(-n2cncn2)cn1 -US20050288289A1,7,CCNC(=O)Oc1cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c2c1C>>CCNC(=O)Oc1cn2ncnc(Oc3ccc(N)cc3F)c2c1C -US20080161308A1,6,CCCCCOc1cc2c(cc1OCc1cccc(C(=O)OC)c1)C(=O)CC2>>CCCCCOc1cc2c(cc1OCc1cccc(C(=O)O)c1)C(=O)CC2 -US08119663B2,6,COC(=O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CC(O)C2)C1>>O=C(O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CC(O)C2)C1 -US20090105324A1,1,CC(C)(C)S(N)=O.Cc1cnc(C=O)n1C>>Cc1cnc(/C=N/S(=O)C(C)(C)C)n1C -US05750300,6,COC1CCC(CBr)CC1>>OC1CCC(CBr)CC1 -US20140031555A1,1,C[C@H]1CO[C@@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12.O=C(COC(=O)OCI)OCc1ccccc1>>C[C@H]1CO[C@@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(OCOC(=O)OCC(=O)OCc4ccccc4)c3C(=O)N12 -US20080249102A1,3,C#Cc1ccccc1.COC(=O)N[C@H](C(=O)NN(Cc1cccc(Br)c1)C[C@@](O)(Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O)C(C)(C)C>>COC(=O)N[C@H](C(=O)NN(Cc1cccc(C#Cc2ccccc2)c1)C[C@@](O)(Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O)C(C)(C)C -US20110105509A1,1,COC(=O)Cn1c(C)c(Cc2ccc(=O)[nH]c2)c2cc(F)ccc21.Fc1cccc(CBr)c1F>>COC(=O)Cn1c(C)c(Cc2ccc(=O)n(Cc3cccc(F)c3F)c2)c2cc(F)ccc21 -US04388463,1,C=CCBr.COc1cccc2c1[C@]13CCN[C@H](C2)[C@@H]1CCC(=O)C3>>C=CCN1CC[C@]23CC(=O)CC[C@H]2[C@H]1Cc1cccc(OC)c13 -US04254127,6,CCOC(=O)CC1CCN(C(C)=O)CC1>>CC(=O)N1CCC(CC(=O)O)CC1 -US07737166B2,6,CCOC(=O)CCCNc1nc2c(C#N)c(C)c(-c3ccccc3)c(N3CC[C@H](N(C)C)C3)c2o1>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(NCCCC(=O)O)nc2c1C#N -US20050009845A1,6,C[Si](C)(C)C#Cc1cc2ncnc(Cl)c2s1>>C#Cc1cc2ncnc(Cl)c2s1 -US06274588B1,6,CCOC(=O)c1cnc(SC)nc1-c1ccccc1Br>>CSc1ncc(C(=O)O)c(-c2ccccc2Br)n1 -US06881736B1,3,C=CC(=O)N1C(=O)N(C)C(C)C1c1ccccc1.Fc1cccc(Br)c1>>CC1C(c2ccccc2)N(C(=O)/C=C/c2cccc(F)c2)C(=O)N1C -US20110230462A1,3,CC1(C)OB(C2=CCCC2)OC1(C)C.Clc1cc(I)ccn1>>Clc1cc(C2=CCCC2)ccn1 -US20110152318A1,1,CC(NC(=O)c1coc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1.Oc1cccc(I)c1>>CC(NC(=O)c1coc(Oc2cccc(I)c2)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1 -US20030144288A1,2,COc1ccc(C2CCCCC2)c2sc(N)nc12.O=C(Cl)c1ccc(CCl)cc1>>COc1ccc(C2CCCCC2)c2sc(NC(=O)c3ccc(CCl)cc3)nc12 -US20100311729A1,1,CC(C)(C)OC(=O)NCCCBr.COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O>>COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1OCCCNC(=O)OC(C)(C)C -US20070197526A1,6,CCOC(=O)c1cc(C)nn1-c1ccc(OC)cc1>>COc1ccc(-n2nc(C)cc2C(=O)O)cc1 -US20130281657A1,1,CC(C)(C)OC(=O)Nc1ncc(C=O)s1.COC(=O)[C@H](CCI)NC(=O)OC(C)(C)C>>COC(=O)[C@H](CCN(C(=O)OC(C)(C)C)c1ncc(C=O)s1)NC(=O)OC(C)(C)C -US20040063691A1,6,O=C(N[C@H]1CCCC[C@@H]1OCc1ccccc1)c1nc(-c2ccccc2Cl)n(-c2ccc(Cl)cc2)c1Br>>O=C(N[C@H]1CCCC[C@@H]1O)c1nc(-c2ccccc2Cl)n(-c2ccc(Cl)cc2)c1Br -US04267326,1,CCCC(=O)OCCl.O=c1[nH]cc(F)c(=O)[nH]1>>CCCC(=O)OCn1cc(F)c(=O)[nH]c1=O -US03997667,1,BrCCCOc1cccc2ccccc12.COc1ccc(N2CCNCC2)cc1>>COc1ccc(N2CCN(CCCOc3cccc4ccccc34)CC2)cc1 -US05877199,1,CSc1c(CC(=O)OC(C)(C)C)cc(C)c2c1[nH]c1ccccc12.Fc1ccc(CBr)cc1>>CSc1c(CC(=O)OC(C)(C)C)cc(C)c2c3ccccc3n(Cc3ccc(F)cc3)c12 -US20100105651A1,1,CC(=O)Cc1ccccc1C.CC(NC(=O)N1CC(N)C1)c1ccc(C(F)(F)F)cc1>>Cc1ccccc1CC(C)NC1CN(C(=O)NC(C)c2ccc(C(F)(F)F)cc2)C1 -US20090298811A1,1,NCCN1CCOCC1.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1NCCN1CCOCC1 -US20130253004A1,3,Cn1ncc(Br)c1C=O.[Mg+]CCCc1ccccc1>>Cn1ncc(Br)c1C(O)CCCc1ccccc1 -US20090264426A1,1,CN(C)CCO.O=[N+]([O-])c1ccc2nc(Cl)ccc2c1>>CN(C)CCOc1ccc2cc([N+](=O)[O-])ccc2n1 -US05064861,6,CCOC(=O)COc1ccc(OCc2ccccc2)c(OC)c1>>COc1cc(OCC(=O)O)ccc1OCc1ccccc1 -US05942532,7,N#Cc1cc([N+](=O)[O-])c(N)c([N+](=O)[O-])c1>>N#Cc1cc(N)c(N)c([N+](=O)[O-])c1 -US04120905,1,CCCCNCC.O=[N+]([O-])c1cc(C(F)(F)F)cc([N+](=O)[O-])c1Cl>>CCCCN(CC)c1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-] -US07173043B2,1,Cc1sc2cc(OCCCCBr)ccc2c1-c1ccc(C(F)(F)F)cc1.OC1CCNCC1>>Cc1sc2cc(OCCCCN3CCC(O)CC3)ccc2c1-c1ccc(C(F)(F)F)cc1 -US20090149501A1,2,COCCO.CS(=O)(=O)Cl>>COCCOS(C)(=O)=O -US07381728B2,2,COc1ccc(N)cc1N1C[C@H](C)N[C@H](C)C1.O=S(=O)(Cl)c1ccc(-c2cccs2)cc1>>COc1ccc(NS(=O)(=O)c2ccc(-c3cccs3)cc2)cc1N1C[C@H](C)N[C@H](C)C1 -US20040176602A1,3,CC1(C)OB(c2cccc(CN3CCOCC3)c2)OC1(C)C.COc1cc(Nc2c(C#N)cnc3cc(Br)ccc23)c(Cl)cc1Cl>>COc1cc(Nc2c(C#N)cnc3cc(-c4cccc(CN5CCOCC5)c4)ccc23)c(Cl)cc1Cl -US04599325,6,COC(=O)[C@@H](C)NC(=O)C(Cc1c(C)cc(O)cc1C)NC(=O)OC(C)(C)C>>Cc1cc(O)cc(C)c1C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C)C(=O)O -US20140142085A1,3,COc1ccc(B(O)O)cc1.O=Cc1ncccc1Br>>COc1ccc(-c2cccnc2C=O)cc1 -US20050124683A1,2,CC(=O)Oc1cc(C)cc(C(=O)N[C@@H](Cc2ccccc2)[C@H](OC(C)=O)C(=O)O)c1C.CCNC(=O)[C@H]1NCC(F)(F)C1(C)C>>CCNC(=O)[C@H]1N(C(=O)[C@@H](OC(C)=O)[C@H](Cc2ccccc2)NC(=O)c2cc(C)cc(OC(C)=O)c2C)CC(F)(F)C1(C)C -US06555557B1,7,CCOC(=O)CCc1c(OC)cncc1OC>>COc1cncc(OC)c1CCCO -US20040116464A1,1,CN(C)c1ccc(C(=O)CBr)cc1.CNCc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2s1>>CN(CC(=O)c1ccc(N(C)C)cc1)Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2s1 -US05321027,1,CC(=O)Nc1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)cc1.CCCI>>CCCN(C(C)=O)c1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)cc1 -US20130035310A1,2,Nc1ccncn1.O=C1CN(C(=O)C(F)(F)F)CCN1c1ccc(S(=O)(=O)Cl)cc1>>O=C1CN(C(=O)C(F)(F)F)CCN1c1ccc(S(=O)(=O)Nc2ccncn2)cc1 -US04269854,7,CCCc1c2c(c(O)c3c(=O)cc(C(=O)O)oc13)C(=O)CCC2>>CCCc1c2c(c(O)c3c(=O)cc(C(=O)O)oc13)C(O)CCC2 -US06787543B2,1,COc1cccc(Cl)c1C=O.c1ccc(C(c2ccccc2)[C@@H]2CNC[C@@H]3CCCN32)cc1>>COc1cccc(Cl)c1CN1C[C@@H]2CCCN2[C@H](C(c2ccccc2)c2ccccc2)C1 -US20040121965A1,2,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](N)C(C)(C)C.CN[C@H](C(=O)O)C(C)(C)c1cccs1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)(C)c1cccs1)C(C)(C)C -US20040121965A1,2,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](N)C(C)(C)C.CN[C@H](C(=O)O)C(C)(C)c1cccs1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](NC)C(C)(C)c1cccs1)C(C)(C)C -US20090030003A1,6,CC(C)n1ncc2c(=O)[nH]c([C@@H]3CN(Cc4ccccc4)C[C@H]3C)nc21>>CC(C)n1ncc2c(=O)[nH]c([C@@H]3CNC[C@H]3C)nc21 -US20140323530A1,2,CCCC(N)CCC.O=C(Cl)c1cccc(Br)c1>>CCCC(CCC)NC(=O)c1cccc(Br)c1 -US20100256134A1,2,CCOC(=O)c1cnn2c(Nc3ccc(C)c(F)c3)c(C(=O)O)cnc12.Fc1ccc2c(c1)OCC21CCNCC1>>CCOC(=O)c1cnn2c(Nc3ccc(C)c(F)c3)c(C(=O)N3CCC4(CC3)COc3cc(F)ccc34)cnc12 -US05360802,7,CCS(=O)(=O)NC(=O)c1cccc([N+](=O)[O-])c1>>CCS(=O)(=O)NC(=O)c1cccc(N)c1 -US07795262B2,6,c1ccc(CN2CCc3ncccc3C2)cc1>>c1cnc2c(c1)CNCC2 -US07326803B2,6,COC(=O)c1ccc(C#C[Se]c2cc(OCc3cccc4ccccc34)c3c(c2)C(C)(C)CCC3(C)C)cc1>>CC1(C)CCC(C)(C)c2c(OCc3cccc4ccccc34)cc([Se]C#Cc3ccc(C(=O)O)cc3)cc21 -US08399681B2,1,FC(F)(F)c1ccc(CBr)c(Br)c1.O=Cc1ccc2[nH]ncc2c1>>O=Cc1ccc2c(cnn2Cc2ccc(C(F)(F)F)cc2Br)c1 -US20150126490A1,6,O=C1c2ccccc2C(=O)N1[C@H](CF)c1ccccc1>>N[C@H](CF)c1ccccc1 -US20140088078A1,6,CC(C)(C)OC(=O)c1c(NC(=O)C(F)(F)F)ccc2c1OCC1CC21>>CC(C)(C)OC(=O)c1c(N)ccc2c1OCC1CC21 -US20100029619A1,1,CC(C)(C)c1ccc(C(=O)Nc2cn3nc(I)ccc3n2)cc1.NCc1ccncc1>>CC(C)(C)c1ccc(C(=O)Nc2cn3nc(NCc4ccncc4)ccc3n2)cc1 -US20120095064A1,4,CC(=O)CCl.CCOC(=O)C(C)(C)C(N)=S>>CCOC(=O)C(C)(C)c1nc(C)cs1 -US09034850B2,1,Cc1c(N2CCNC(CO)C2)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F.FC(F)(F)c1ccc(CBr)o1>>Cc1c(N2CCN(Cc3ccc(C(F)(F)F)o3)C(CO)C2)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F -US20150259366A1,2,CCCCCCCc1ccc(CNc2ccc(O)c(C(=O)OC)c2)cc1.O=C(Cl)c1cccnc1>>CCCCCCCc1ccc(CN(C(=O)c2cccnc2)c2ccc(O)c(C(=O)OC)c2)cc1 -US20140371199A1,2,CC(=O)Cl.CN(C)C1CCN(C(=O)c2ccc(Br)cc2N)CC1>>CC(=O)Nc1cc(Br)ccc1C(=O)N1CCC(N(C)C)CC1 -US08080552B2,2,CSc1nccc(Oc2ccc(N)cc2)n1.O=C=Nc1cccc(C(F)(F)F)c1>>CSc1nccc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)n1 -US20150274695A1,3,COc1cc(F)ccc1B(O)O.Nc1cc(Cl)ncn1>>COc1cc(F)ccc1-c1cc(N)ncn1 -US20120136163A1,2,CC(=O)Cl.CC1(C)CNc2cc([N+](=O)[O-])ccc21>>CC(=O)N1CC(C)(C)c2ccc([N+](=O)[O-])cc21 -US04348223,1,CC(Cl)c1cccc([N+](=O)[O-])c1.C[O-]>>COC(C)c1cccc([N+](=O)[O-])c1 -US20120225062A1,3,C[Mg+].O=C1CCOc2c(F)cc(F)cc21>>CC1(O)CCOc2c(F)cc(F)cc21 -US20080045521A1,3,C#CCCCO.COC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)NC(=O)c1c(Cl)cccc1Cl>>COC(=O)[C@H](Cc1ccc(C#CCCCO)cc1)NC(=O)c1c(Cl)cccc1Cl -US20090176786A1,1,CI.Cc1c(SC(F)F)ccc(N(C)C(=O)NC(=O)c2c(F)cccc2F)c1C>>Cc1c(SC(F)F)ccc(N(C)C(=O)N(C)C(=O)c2c(F)cccc2F)c1C -US06096766,1,CC(=O)Nc1ccc(O)c(C(C)=O)c1.CI>>COc1ccc(NC(C)=O)cc1C(C)=O -US09035063B2,7,O=[N+]([O-])c1cnc(Cl)c(C(F)(F)F)c1>>Nc1cnc(Cl)c(C(F)(F)F)c1 -US07230001B1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C1NC(Cc2ccccc2)C(=O)N1C1CCNCC1>>CC(C)(C)OC(=O)N1CCC(N2CCC(N3C(=O)NC(Cc4ccccc4)C3=O)CC2)CC1 -US08445684B2,7,CC(C)C(=O)OC[C@H]1C[C@@H]1c1cncc(OC[C@@H]2CCN2C(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc([C@H]2C[C@@H]2CO)c1 -US08748426B2,2,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O.O=C=Nc1ccc(F)cc1F>>COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)Nc4ccc(F)cc4F)cc3)cc2C1=O -US09149465B2,1,BrC1=NOCC1.Oc1cncnc1>>c1ncc(OC2=NOCC2)cn1 -US04680400,3,Cc1c(C)c(Br)c2ncccc2c1C.O=CN1CCCCC1>>Cc1c(C)c(C=O)c2ncccc2c1C -US20100272680A1,2,CC1(N2CCOC2=O)CCNCC1.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl>>CC1(N2CCOC2=O)CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)CC1 -US20150094297A1,1,COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1.O=Cc1sc(N2CCOCC2)nc1CO>>COc1cc(OCc2nc(N3CCOCC3)sc2C=O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US07091357B2,7,CC(C)=CCCCCCO>>CC(C)CCCCCCO -US07649001B2,1,C1CCONC1.N#Cc1ccc(F)c2ccccc12>>N#Cc1ccc(N2CCCCO2)c2ccccc12 -US20140249139A1,3,CC(=O)N1CCN(C(=O)c2cc(-c3ncnc4ccc(Br)cc34)ccn2)CC1.COc1ncc(B(O)O)cn1>>COc1ncc(-c2ccc3ncnc(-c4ccnc(C(=O)N5CCN(C(C)=O)CC5)c4)c3c2)cn1 -US04665073,2,COC(=O)c1cccc(-n2ncc(NC(N)=NCC(F)(F)F)n2)c1.NCCO>>NC(=NCC(F)(F)F)Nc1cnn(-c2cccc(C(=O)NCCO)c2)n1 -US20050054627A1,6,COC(=O)c1cccc(-c2nccs2)c1>>O=C(O)c1cccc(-c2nccs2)c1 -US20070072865A1,6,CC(C)(C)OC(=O)n1cnc2c(NC(=O)N3CCN4C(=O)OC(c5ccccc5)(c5ccccc5)C4C3)cccc21>>O=C(Nc1cccc2[nH]cnc12)N1CCN2C(=O)OC(c3ccccc3)(c3ccccc3)C2C1 -US09085578B2,7,COc1ccn(-c2c(F)cc([N+](=O)[O-])cc2F)c(=O)c1C#N>>COc1ccn(-c2c(F)cc(N)cc2F)c(=O)c1C#N -US04140793,1,COC(=O)CBr.C[C@H]1CC[C@H](C)N1>>COC(=O)CN1[C@@H](C)CC[C@@H]1C -US20120295915A1,3,Brc1ccnc2[nH]ccc12.O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)nc3cnccc32)C1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(-c4ccnc5[nH]ccc45)cc3)nc3cnccc32)C1 -US20130059849A1,2,CCCc1cc(C(=O)O)c2cnn(C(C)C)c2n1.Cc1cc(C)c(CN)c(=O)[nH]1>>CCCc1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c2cnn(C(C)C)c2n1 -US04668697,1,CN(C)CCS.NS(=O)(=O)c1cc2cc(CBr)ccc2s1>>CN(C)CCSCc1ccc2sc(S(N)(=O)=O)cc2c1 -US20120004164A1,1,Cc1nc(CBr)nn1-c1ccccc1.Cc1nc(N2CCNC2=O)sc1C(=O)NCc1ccccc1>>Cc1nc(N2CCN(Cc3nc(C)n(-c4ccccc4)n3)C2=O)sc1C(=O)NCc1ccccc1 -US20140235863A1,4,NC(=S)Nc1ccccc1C(F)(F)F.O=C(CBr)c1ccc(F)cc1>>Fc1ccc(-c2csc(Nc3ccccc3C(F)(F)F)n2)cc1 -US20120295897A1,1,BrCc1nc2ccccc2s1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCO3>>O=C1N(Cc2nc3ccccc3s2)c2ccccc2C12COc1cc3c(cc12)OCCO3 -US06951879B2,1,BrCCCCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1.COCCNCCOC>>COCCN(CCCCOc1ccc2c(-c3ccc(Br)cc3)nsc2c1)CCOC -US07713950B2,8,CSc1ccc([C@H]2OC(c3ccccc3)=N[C@@H]2CO)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc([C@H]2OC(c3ccccc3)=N[C@@H]2CO)cc1 -US20040072827A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CNCCCn1c(-c2ccc(F)cc2)csc1=Nc1ccc(Cl)cc1OC>>CCOC(=O)CN(CCCn1c(-c2ccc(F)cc2)csc1=Nc1ccc(Cl)cc1OC)C(=O)OC(C)(C)C -US20080132551A1,7,CCOc1ccc([N+](=O)[O-])c(Br)c1>>CCOc1ccc(N)c(Br)c1 -US20150025065A1,1,CS(C)(=O)=Nc1ccc2c(n1)CNC2.C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)nc2cc(Cl)c(-c3ccc(Br)cc3)nc21>>C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)nc2cc(Cl)c(-c3ccc(N4Cc5ccc(N=S(C)(C)=O)nc5C4)cc3)nc21 -US05132314,7,O=C(O)c1cc(Cl)ccc1[N+](=O)[O-]>>Nc1ccc(Cl)cc1C(=O)O -US07563793B2,2,CC1Nc2cc(Br)ccc2-n2cccc21.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)N2c3cc(Br)ccc3-n3cccc3C2C)c1 -US05567722,7,CC(=O)Nc1ccc([N+](=O)[O-])cn1>>CC(=O)Nc1ccc(N)cn1 -US05990116,1,COc1ccc(OC)c(C=O)c1.Nc1ccc2nc[nH]c(=O)c2c1>>COc1ccc(OC)c(CNc2ccc3nc[nH]c(=O)c3c2)c1 -US04792208,2,C=CC(=O)Cl.CN(CCCCCCO)c1ccc(C=Cc2ccc(S(C)(=O)=O)cc2)cc1>>C=CC(=O)OCCCCCCN(C)c1ccc(C=Cc2ccc(S(C)(=O)=O)cc2)cc1 -US04029704,1,CC(C)CCCCCCCBr.O=C(Cc1ccccc1)c1cc(O)ccc1O>>CC(C)CCCCCCCOc1ccc(O)c(C(=O)Cc2ccccc2)c1 -US20100063068A1,6,CCN(c1cn2nc(-c3ccc(F)cc3)c(C(=O)NC)c2cc1OCc1ccccc1)S(C)(=O)=O>>CCN(c1cn2nc(-c3ccc(F)cc3)c(C(=O)NC)c2cc1O)S(C)(=O)=O -US20150152112A1,7,Nc1cc(-n2cccn2)ccc1[N+](=O)[O-]>>Nc1ccc(-n2cccn2)cc1N -US20100168105A1,1,O=C(C1CC12CCNCC2)N1CCN(C2CCCCC2)CC1.O=CCOCc1ccccc1>>O=C(C1CC12CCN(CCOCc1ccccc1)CC2)N1CCN(C2CCCCC2)CC1 -US05102667,7,CC(=O)O[C@H](C(=O)N1C[C@@H]2C(=O)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1)c1ccccc1>>O=C1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CN(C(=O)[C@@H](O)c3ccccc3)C[C@H]12 -US20100168088A1,6,CN(C(=O)OC(C)(C)C)C1CN(C(=O)c2ccc(C#N)cc2)CC1c1ccc(Cl)c(Cl)c1>>CNC1CN(C(=O)c2ccc(C#N)cc2)CC1c1ccc(Cl)c(Cl)c1 -US08748632B2,7,O=C1c2ccc(O)cc2C(=O)N1C1CCCC1>>O=C1c2ccc(O)cc2CN1C1CCCC1 -US20150005282A1,6,COC(=O)C[C@@H]1COc2cc(OCc3cc(-c4c(C)cc(O[C@@H]5CCOC5)cc4C)ccc3OCc3ccccc3)ccc21>>Cc1cc(O[C@@H]2CCOC2)cc(C)c1-c1ccc(OCc2ccccc2)c(COc2ccc3c(c2)OC[C@H]3CC(=O)O)c1 -US20130059847A1,1,C=CC(=O)Nc1cccc(-c2nc(Cl)nc3c2cnn3C2CCCCO2)c1.Nc1ccc(N2CCOCC2)c(F)c1>>C=CC(=O)Nc1cccc(-c2nc(Nc3ccc(N4CCOCC4)c(F)c3)nc3c2cnn3C2CCCCO2)c1 -US09018394B2,6,CC(C)(C)OC(=O)N1C(=O)CCc2ccccc21>>O=C1CCc2ccccc2N1 -US20140057896A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCc2c(sc3c2CCCC3)C1=O.CN1CC(c2ccc(Nc3cc(Br)cn(C)c3=O)nc2)C1>>CC(=O)OCc1c(-c2cc(Nc3ccc(C4CN(C)C4)cn3)c(=O)n(C)c2)cccc1N1CCc2c(sc3c2CCCC3)C1=O -US06518273B1,6,CCOC(=O)Cc1c(-c2ccccc2)[nH]c2ccc(C)cc12>>Cc1ccc2[nH]c(-c3ccccc3)c(CC(=O)O)c2c1 -US20090136473A1,7,COc1ccc(C(=O)c2ccc([N+](=O)[O-])cc2)cc1-c1cccc(Cl)c1>>COc1ccc(C(=O)c2ccc(N)cc2)cc1-c1cccc(Cl)c1 -US04868310,2,C=CC#N.CC(C)(C)O>>C=CC(=O)NC(C)(C)C -US20090221740A1,6,CCCCC(CC)CC(CC(CC)CCCC)N1C(=O)c2ccccc2C1=O>>CCCCC(CC)CC(N)CC(CC)CCCC -US20100311966A1,2,CCCCOC(=O)c1nc(N2CC[C@H](N)[C@H](OC)C2)oc1C(C)C.CCc1[nH]c(C(=O)O)nc1Cl>>CCCCOC(=O)c1nc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](OC)C2)oc1C(C)C -US05756816,6,CCOCCCCCC(OC(=O)c1ccc(OCc2ccccc2)cc1F)C(F)(F)F>>CCOCCCCCC(OC(=O)c1ccc(O)cc1F)C(F)(F)F -US20070293532A1,6,CCCn1c(C)cc2ccnc(NCc3ccccc3)c21>>CCCn1c(C)cc2ccnc(N)c21 -US05262385,7,COC(=O)C1(F)CCCCCC1=O>>COC(=O)C1(F)CCCCCC1O -US20040192653A1,1,Cc1cc(Cl)ncc1[N+](=O)[O-].N#Cc1cc(F)ccc1O>>Cc1cc(Oc2ccc(F)cc2C#N)ncc1[N+](=O)[O-] -US05998433,3,C=O.CNC.O=C1c2ccccc2S(=O)(=O)c2cc(C(=O)N3CCc4ccoc4C3)ccc21>>CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc3c(c1)S(=O)(=O)c1ccccc1C3=O)CC2 -US20090118296A1,4,CC(=O)NNC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1>>Cc1nnc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nn2)o1 -US20080318874A1,1,BrCc1ccccc1.Cc1cccc(C=O)c1O>>Cc1cccc(C=O)c1OCc1ccccc1 -US20150250169A1,2,CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(OS(=O)(=O)c2ccc(C)cc2)=C1O -US05674886,1,BrCc1cnc(Br)s1.N#Cc1ccc(Nn2cnnc2)cc1>>N#Cc1ccc(N(Cc2cnc(Br)s2)n2cnnc2)cc1 -US06376535B2,7,CCOC(=O)C=C1CCC(C#N)(c2ccc(OC)c3c2OCCO3)CC1>>CCOC(=O)CC1CCC(C#N)(c2ccc(OC)c3c2OCCO3)CC1 -US20110243844A1,7,O=[N+]([O-])c1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1>>Nc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1 -US20110207704A1,2,CO.O=C(O)c1cnc(O)c(Br)c1>>COC(=O)c1cnc(O)c(Br)c1 -US20070173486A1,2,Clc1ccc(C(OC2CCNCC2)c2ccc(Cl)cc2)cc1.O=S(=O)(Cl)c1ccccc1F>>O=S(=O)(c1ccccc1F)N1CCC(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 -US20150099777A1,6,CCOc1cc(-c2ccc(F)cc2)c(C2CC2)cc1CN1CCC(N2CCc3nc(C4CC4)c(C(=O)OC)cc3C2=O)CC1>>CCOc1cc(-c2ccc(F)cc2)c(C2CC2)cc1CN1CCC(N2CCc3nc(C4CC4)c(C(=O)O)cc3C2=O)CC1 -US20040235816A1,1,CC(C)C=O.O=S(=O)(C=C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)Cc1cccc(N2CCNCC2)c1>>CC(C)CN1CCN(c2cccc(CS(=O)(=O)C=C3CN(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)C3)c2)CC1 -US04021461,7,CC(C)=CCC(C)C=O>>CC(C)CCC(C)C=O -US20150158882A1,6,Cc1[nH]ncc1-c1cc2nc([C@@H]3C4CCC(CC4)N3C(=O)OC(C)(C)C)[nH]c(=O)c2s1>>Cc1[nH]ncc1-c1cc2nc([C@H]3NC4CCC3CC4)[nH]c(=O)c2s1 -US20120323040A1,1,Fc1cccc(S)c1.O=C1CCCc2cc(F)ccc21>>O=C1CCCc2cc(Sc3cccc(F)c3)ccc21 -US20140288066A1,1,C[C@H]1COCCN1.Clc1nc(Cl)c2c(n1)CCS2>>C[C@H]1COCCN1c1nc(Cl)nc2c1SCC2 -US06861438B2,7,CCOC(=O)c1c[nH]c2cc(C=O)sc2c1=O>>CCOC(=O)c1c[nH]c2cc(CO)sc2c1=O -US20060030600A1,6,CC(C)(C)[SiH2]OC(C)(C)c1cncc(OCc2ccccc2)c1>>CC(C)(C)[SiH2]OC(C)(C)c1cncc(O)c1 -US08969394B2,2,Cc1sc(C)c(C(=O)N[C@@H](C)c2ccc(C(=O)O)cc2)c1Cc1ccc(C(F)(F)F)cc1.NS(=O)(=O)c1ccccc1>>Cc1sc(C)c(C(=O)N[C@@H](C)c2ccc(C(=O)NS(=O)(=O)c3ccccc3)cc2)c1Cc1ccc(C(F)(F)F)cc1 -US08318949B2,6,CCOC(=O)c1sc(N2C[C@H](C)N(Cc3ccc(F)cc3)C2=O)nc1C>>Cc1nc(N2C[C@@H](C)N(Cc3ccc(F)cc3)C2=O)sc1C(=O)O -US06492384B1,1,Cc1nc(-c2cccc(Cn3c(C(C)C)nc4cc[nH]c(=O)c43)c2)no1.N#Cc1cccc(B(O)O)c1>>Cc1nc(-c2cccc(Cn3c(C(C)C)nc4ccn(-c5cccc(C#N)c5)c(=O)c43)c2)no1 -US06881736B1,6,CCOC(=O)CC(Cc1ccc(OC)cc1)c1ccc(C(F)(F)F)cc1>>CCOC(=O)CC(Cc1ccc(O)cc1)c1ccc(C(F)(F)F)cc1 -US20040162303A1,2,CCSc1ncc(C(=O)O)c(N)n1.CNOC>>CCSc1ncc(C(=O)N(C)OC)c(N)n1 -US20080269267A1,3,CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Nc1ccc(Oc2ccnc(Cl)c2)cc1F>>CCn1cc(-c2cc(Oc3ccc(N)c(F)c3)ccn2)cn1 -US06982348B2,7,CCOC(=O)C(C)(C)c1cccc(C)c1>>Cc1cccc(C(C)(C)CO)c1 -US20150252038A1,1,COC(=O)c1cc(C2CC2)c(OC[C@@H]2CCCNC2)cc1F.Fc1ccc(CBr)c(Cl)c1>>COC(=O)c1cc(C2CC2)c(OC[C@@H]2CCCN(Cc3ccc(F)cc3Cl)C2)cc1F -US20090030015A1,6,COC(=O)Cc1ccc(-c2cccc(NC(=O)c3cccc(-c4ccc(OC)cc4OC)c3)c2)s1>>COc1ccc(-c2cccc(C(=O)Nc3cccc(-c4ccc(CC(=O)O)s4)c3)c2)c(OC)c1 -US20070191431A1,2,O=C(Cl)c1ccccc1.OCC1CCNCC1>>O=C(c1ccccc1)N1CCC(CO)CC1 -US03948973,6,COc1ccc(C2C(C)(C)C2(F)F)cc1>>CC1(C)C(c2ccc(O)cc2)C1(F)F -US20070249670A1,6,COC(=O)C1(NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(Cl)cc(Cl)cc2Cl)CCCCCC1>>O=C(Nc1cc2ccccc2cc1C(=O)NC1(C(=O)O)CCCCCC1)Nc1c(Cl)cc(Cl)cc1Cl -US04013641,1,CN1C(=O)c2[nH]c3cc(Cl)ccc3c2Oc2ccccc21.ClCCN1CCCCC1>>CN1C(=O)c2c(c3ccc(Cl)cc3n2CCN2CCCCC2)Oc2ccccc21 -US20030162777A1,2,O=C(Cl)C1CCCCC1.c1ccc2c(c1)CCC(CN1CCN(c3cccc4[nH]ccc34)CC1)N2>>O=C(C1CCCCC1)N1c2ccccc2CCC1CN1CCN(c2cccc3[nH]ccc23)CC1 -US04210754,2,COC(=O)c1ccc(Cl)cc1.NCCN1CCOCC1>>O=C(NCCN1CCOCC1)c1ccc(Cl)cc1 -US20030078265A1,2,NCCc1ccc2c(c1)OCO2.O=C(Cl)CCl>>O=C(CCl)NCCc1ccc2c(c1)OCO2 -US20110015232A1,2,CC(C)(C)OC(=O)N[C@H](C(=O)O)C1CCCCC1.c1ccc2c(c1)ncn2-c1cc([C@@H]2CCCN2)ccn1>>CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ccnc(-n2cnc3ccccc32)c1)C1CCCCC1 -US20140194628A1,7,CC(C)(C)[Si](C)(C)OCCCCNc1c([N+](=O)[O-])cnc2ccccc12>>CC(C)(C)[Si](C)(C)OCCCCNc1c(N)cnc2ccccc12 -US06271264B1,1,C=CCBr.c1ccc2c(c1)CCNC2>>C=CCN1CCc2ccccc2C1 -US08541457B2,2,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(Cl)Cc1ccccc1>>Cc1nc(NC(=O)Cc2ccccc2)sc1C(=O)NCc1ccccc1 -US20060063784A1,1,Cc1ccccc1C=O.Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1>>Cc1ccccc1CNc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 -US20050043368A1,2,C[C@H](NC(=O)OC(C)(C)C)[C@H](O)CN.O=S(=O)(Cl)c1ccccn1>>C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CNS(=O)(=O)c1ccccn1 -US05519015,6,CCOC(=O)c1sc(C(=O)OC(C)(C)C)cc1OC(C)(C)C>>CC(C)(C)OC(=O)c1cc(OC(C)(C)C)c(C(=O)O)s1 -US20100093757A1,1,CCOC[C@H](O)C(=O)OC.Clc1cccnc1-n1ncc2c(Cl)ncnc21>>CCOC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)OC -US20150225412A1,7,COC(=O)c1ccc2c(c1)nc(NC(=O)c1ccno1)n2C[C@H]1CCCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccno2)nc2cc(CO)ccc21 -US20130338081A1,7,COC(=O)[C@@H]1Cc2ccc(C3=C[C@@H](C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)OC(C)(C)C)C3)cc2CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1Cc2ccc([C@H]3C[C@@H](C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)OC(C)(C)C)C3)cc2CN1C(=O)OC(C)(C)C -US20100292279A1,1,COC(=O)c1ccc(Br)c(O)c1.OCC1CC1>>COC(=O)c1ccc(Br)c(OCC2CC2)c1 -US20070219212A1,7,CCCC1(CC(=O)OCC)OCCc2c1[nH]c1c(C)c(C(=O)O)cc(C#N)c21>>CCCC1(CC(=O)OCC)OCCc2c1[nH]c1c(C)c(CO)cc(C#N)c21 -US20090318385A1,3,CC[Mg+].COc1ccc(C=O)c2cc(C(F)F)nn12>>CCC(O)c1ccc(OC)n2nc(C(F)F)cc12 -US20140235614A1,1,CCOCCBr.O=Cc1ccc(O)c(O)c1>>CCOCCOc1ccc(C=O)cc1O -US07888352B2,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.C[C@H](O)C(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1>>C[C@H](O)C(=O)N1CCN(Cc2cc3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3s2)CC1 -US20030171411A1,2,Nc1ccccn1.O=C(O)C(SC1CCCC1)c1cccc(OC(F)(F)F)c1>>O=C(Nc1ccccn1)C(SC1CCCC1)c1cccc(OC(F)(F)F)c1 -US20020150936A1,2,CC(C)C(=O)Cl.Nc1nc2nc[nH]c2c(=O)n1[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O>>CC(C)C(=O)Nc1nc2nc[nH]c2c(=O)n1[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O -US06821967B2,2,COCCCN.O=C(O)C1(CCCCBr)c2ccccc2-c2ccccc21>>COCCCNC(=O)C1(CCCCBr)c2ccccc2-c2ccccc21 -US07229987B2,2,NNC(=O)c1ccc(O)cc1.O=C(O)CSCCOc1ccccc1>>O=C(CSCCOc1ccccc1)NNC(=O)c1ccc(O)cc1 -US07247625B2,1,CC(=O)c1cccc(B(O)O)c1.CCC1(CC)OC(=O)N(C)c2ccc(N)cc21>>CCC1(CC)OC(=O)N(C)c2ccc(Nc3cccc(C(C)=O)c3)cc21 -US20140171315A1,6,CC(C)(C)OC(=O)N1CCC(NC(=O)c2ccc(/C=C/C(c3cc(Cl)c(Cl)c(Cl)c3)C(F)(F)F)cc2Br)CC1>>O=C(NC1CCNCC1)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1Br -US20100298356A1,6,COc1cc(C)c2ccsc2c1>>Cc1cc(O)cc2sccc12 -US05807885,5,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])c1cccc(CCNCCc2ccccc2)c1>>O=C(N(CCc1ccccc1)CCc1cccc([N+](=O)[O-])c1)C(F)(F)F -US05550134,1,CI.C[C@]12CCC(=O)N[C@@H]1CCc1cc(-c3ccc(C#N)cc3)ccc12>>CN1C(=O)CC[C@]2(C)c3ccc(-c4ccc(C#N)cc4)cc3CC[C@@H]12 -US06291475B1,4,C=CCC(OC(C)=O)c1ccc(C#N)cc1.O=C(OO)c1cccc(Cl)c1>>CC(=O)OC(CC1CO1)c1ccc(C#N)cc1 -US07786104B2,2,CCOC(=O)c1cc2cc(F)ccc2n1Cc1cccc(F)c1.Nc1ccc(Cl)nc1>>O=C(Nc1ccc(Cl)nc1)c1cc2cc(F)ccc2n1Cc1cccc(F)c1 -US20020019527A1,3,COC(=O)c1cnc(C#N)c(Cl)c1.OB(O)c1cccc2ccccc12>>COC(=O)c1cnc(C#N)c(-c2cccc3ccccc23)c1 -US06960578B2,3,Brc1ccccn1.C#Cc1ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)Nc1ccc(C#Cc2ccccn2)cc1[N+](=O)[O-] -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3ccc(F)cc3)cc2)cc1)Oc1ccccc1>>O=C(NCCOc1ccc(CC(Oc2ccccc2)C(=O)O)cc1)c1ccc(-c2ccc(F)cc2)cc1 -US20090156596A1,7,CNc1ncnc2c1ncn2/C=C/c1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1C>>CNc1ncnc2c1ncn2CCc1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1C -US20050148627A1,1,CCOC(=O)C1=Cc2cc(Cl)c(F)cc2OC1C(F)(F)F.Cc1cc(O)c(Cl)cc1C>>CCOC(=O)C1=Cc2cc(Cl)c(Oc3cc(C)c(C)cc3Cl)cc2OC1C(F)(F)F -US06685995B1,7,CCCCCC1CCC(CCC2=CCC(C3CCC(=O)CC3)CC2)CC1>>CCCCCC1CCC(CCC2=CCC(C3CCC(O)CC3)CC2)CC1 -US08334292B1,1,COCc1nc(Cl)nc(Cl)c1Br.OC1COC1>>COCc1nc(Cl)nc(OC2COC2)c1Br -US08124638B2,1,BrCc1ccc(Br)cc1.c1nnn[nH]1>>Brc1ccc(Cn2cnnn2)cc1 -US04409228,1,Brc1cccc(Br)n1.CC(=O)NC1CCNCC1>>CC(=O)NC1CCN(c2cccc(Br)n2)CC1 -US20060122235A1,2,CN.COC(=O)C1CC(=O)N(c2ccc(/C=C/c3ccc(OC)cc3)cc2)C1>>CNC(=O)C1CC(=O)N(c2ccc(/C=C/c3ccc(OC)cc3)cc2)C1 -US04899249,5,CCCCNCCCC.CCOC(=O)C(F)(F)F>>CCCCN(CCCC)C(=O)C(F)(F)F -US20130065923A1,2,Cc1nc(N2CC[C@@H](N3CCC[C@@H]3C)C2)ccc1N.O=S(=O)(Cl)c1ccc(F)cc1>>Cc1nc(N2CC[C@@H](N3CCC[C@@H]3C)C2)ccc1NS(=O)(=O)c1ccc(F)cc1 -US20110118231A1,3,C=CC#N.COC(=O)c1cc(Cl)ccc1Br>>COC(=O)c1cc(Cl)ccc1/C=C/C#N -US08207214B2,1,BrCc1ccccc1.c1ccc2c(c1)[nH]c1ccccc12>>c1ccc(Cn2c3ccccc3c3ccccc32)cc1 -US20030158245A1,3,CC(C)(C)OC(=O)CSC(NCc1ccccc1)=C1C(=O)CCCC1=O>>CC(C)(C)OC(=O)c1sc(NCc2ccccc2)c2c1CCCC2=O -US08247412B2,6,CCOC(=O)c1cc(-c2csc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)n2)on1>>O=C(O)c1cc(-c2csc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)n2)on1 -US20130324530A1,1,CS(=O)(=O)OC[C@H]1CCCO1.N[C@@H]1CC[C@@H](Nc2cc(-c3cc(NCC4CCOCC4)cnc3Cl)c(Cl)cn2)CC1>>Clc1cnc(N[C@@H]2CC[C@@H](NC[C@H]3CCCO3)CC2)cc1-c1cc(NCC2CCOCC2)cnc1Cl -US04610991,1,Clc1ccncc1.Nc1ccccc1C(=O)O>>O=C(O)c1ccccc1Nc1ccncc1 -US20080119486A1,6,COC(=O)c1cc(C(C)=O)ccc1OC(C)C>>CC(=O)c1ccc(OC(C)C)c(C(=O)O)c1 -US20090023729A1,6,CCCN(CC1CC1)c1nc(OC)ncc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCCC(=O)OCC)cn1>>CCCN(CC1CC1)c1nc(OC)ncc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCCC(=O)O)cn1 -US20150284370A1,3,CCN(c1cc(B2OC(C)(C)C(C)(C)O2)cc(C(=O)OC)c1C)C1CCOCC1.CN1CCCN(c2ccc(I)cn2)CC1>>CCN(c1cc(-c2ccc(N3CCCN(C)CC3)nc2)cc(C(=O)OC)c1C)C1CCOCC1 -US08222248B2,7,COC(=O)C=Cc1cc(C)c(C=O)c(C)c1>>COC(=O)CCc1cc(C)c(C=O)c(C)c1 -US20120088750A1,1,CCOC(=O)C1(C)CCN(c2ncc(-c3cc(CI)c4sc(N5CN(C)CN(CC)C5=O)nc4c3)cn2)CC1.COCCO>>CCOC(=O)C1(C)CCN(c2ncc(-c3cc(COCCOC)c4sc(N5CN(C)CN(CC)C5=O)nc4c3)cn2)CC1 -US05234946,7,CCOC(=O)c1cccc(-c2ccco2)c1>>OCc1cccc(-c2ccco2)c1 -US04248859,2,CCC1(C(=O)Cl)CCCCCCC1.CCOC(=O)CN>>CCOC(=O)CNC(=O)C1(CC)CCCCCCC1 -US20070004717A1,7,COC(=O)c1ccc(C#N)c(Cl)c1C>>Cc1c(CO)ccc(C#N)c1Cl -US08981131B2,2,CC(=O)OC(C)=O.CC1=C2[C@H]3OC(=O)C(CNCC4C(=O)O[C@H]5C6=C(C)CCC[C@]6(C)CCC45O)C3(O)CC[C@]2(C)CCC1>>CC(=O)N(CC1C(=O)O[C@H]2C3=C(C)CCC[C@]3(C)CCC12O)CC1C(=O)O[C@@H]2C3=C(C)CCC[C@@]3(C)CCC12O -US07666864B2,1,C=CCC(O)(Cn1cc([N+](=O)[O-])nc1Cl)c1ccc(Br)cc1>>C=CCC1(c2ccc(Br)cc2)Cn2cc([N+](=O)[O-])nc2O1 -US07625908B2,1,C[C@@H](N)CO.Oc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl>>C[C@@H](N)COc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12 -US20110105436A1,4,NC(=S)Nc1ccc2c(c1)CCC2.O=C(CBr)c1ccncc1>>c1cc(-c2csc(Nc3ccc4c(c3)CCC4)n2)ccn1 -US04757080,6,COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2C(=O)c3ccccc3C2=O)C1c1ccccc1[N+](=O)[O-]>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN)C1c1ccccc1[N+](=O)[O-] -US07655641B2,1,CCCI.Cc1c(S(=O)(=O)NC[C@H](C)O)sc2cc(Cl)c(F)cc12>>CCCN(C[C@H](C)O)S(=O)(=O)c1sc2cc(Cl)c(F)cc2c1C -US06949648B2,1,Cc1cc(N)n(-c2ccccn2)n1.O=C(O)c1cc(C(F)(F)F)ccc1Cl>>Cc1cc(Nc2ccc(C(F)(F)F)cc2C(=O)O)n(-c2ccccn2)n1 -US20030176447A1,1,Cc1nc2cc(OC[C@@H](O)CN3CCNCC3)ccc2s1.Fc1cccc(-c2nc(CCl)no2)c1>>Cc1nc2cc(OCC(O)CN3CCN(Cc4noc(-c5cccc(F)c5)n4)CC3)ccc2s1 -US05411963,1,CC(C)c1ccc(CCN)cc1.Fc1cccc2c(Cl)ncnc12>>CC(C)c1ccc(CCNc2ncnc3c(F)cccc23)cc1 -US06297233B1,2,CNC.COC(=O)c1ccc(C(=O)OC)nc1>>COC(=O)c1ccc(C(=O)N(C)C)nc1 -US20120093766A1,1,CC(C)(C)OC(=O)c1ccc(Nc2nc(Cl)nc(OCC(F)(F)F)n2)cc1.NC1(c2cccc(Br)c2)CC1>>CC(C)(C)OC(=O)c1ccc(Nc2nc(NC3(c4cccc(Br)c4)CC3)nc(OCC(F)(F)F)n2)cc1 -US20090227625A1,6,COC(=O)c1ccc2ccccc2c1OC(C)COc1ccccc1>>CC(COc1ccccc1)Oc1c(C(=O)O)ccc2ccccc12 -US20080188481A1,2,CC(C)(C)OC(=O)N1CCC(=C(C(=O)O)c2ccccc2)CC1.NN>>CC(C)(C)OC(=O)N1CCC(=C(C(=O)NN)c2ccccc2)CC1 -US20060074096A1,7,CCCn1c(-c2ccnc(Nc3ccccc3)n2)cnc1C=CC(C)(C)C>>CCCn1c(-c2ccnc(Nc3ccccc3)n2)cnc1CCC(C)(C)C -US20120232096A1,1,COc1c(C)c(Br)c(C)c2c1OC(C)C2.COc1cccc(N2CCNCC2)c1>>COc1cccc(N2CCN(c3c(C)c4c(c(OC)c3C)OC(C)C4)CC2)c1 -US08288412B2,6,COc1cc2c(cc1Cl)[nH]c(=O)n2C1CCN(C(=O)OC(C)(C)C)CC1>>COc1cc2c(cc1Cl)[nH]c(=O)n2C1CCNCC1 -US20060135773A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1ccc(I)cc1>>CC(C)(C)OC(=O)NCc1ccc(I)cc1 -US05030724,6,CN(NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CNNC(=O)OC(C)(C)C -US20110077399A1,2,CC(C)CN.COc1ccc(/C=C/c2nc(-c3ccc(Cl)cc3Cl)cn2CC(=O)O)cc1>>COc1ccc(/C=C/c2nc(-c3ccc(Cl)cc3Cl)cn2CC(=O)NCC(C)C)cc1 -US05135955,1,BrCC1CCCCC1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCC2CCCCC2)cc1 -US20150191495A1,1,CSCC1CNC1.Cc1nc(F)ccc1Br>>CSCC1CN(c2ccc(Br)c(C)n2)C1 -US20100105700A1,6,CC(C)(C)OC(=O)N1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12>>C[C@]12CCC(=O)C=C1NC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 -US08293734B2,6,CC(C)[Si](OCC1(C)CCn2cc([N+](=O)[O-])nc2O1)(C(C)C)C(C)C>>CC1(CO)CCn2cc([N+](=O)[O-])nc2O1 -US20110201625A1,2,CN(C)CCN.COC(=O)c1nc(Cl)c(N)nc1N>>CN(C)CCNC(=O)c1nc(Cl)c(N)nc1N -US20100204196A1,1,CN(C)C(=O)CCl.COc1cc2c(cc1[N+](=O)[O-])NCC2>>COc1cc2c(cc1[N+](=O)[O-])N(CC(=O)N(C)C)CC2 -US20080280933A1,1,CN.O=[N+]([O-])c1cccc(Br)c1Cl>>CNc1c(Br)cccc1[N+](=O)[O-] -US08916599B2,2,CCOC(=O)c1cc(N)c(NC)cc1F.S=C=Nc1c(Cl)cccc1Cl>>CCOC(=O)c1cc(NC(=S)Nc2c(Cl)cccc2Cl)c(NC)cc1F -US20050239781A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1CN1CCOC[C@H]1C(=O)Nc1cc(Cl)cc2c1[nH]c1cnccc12>>O=C(Nc1cc(Cl)cc2c1[nH]c1cnccc12)[C@@H]1COCCN1C[C@H]1CCCN1 -US06020345,7,CC(=O)c1cccc(C2OCCO2)n1>>CC(O)c1cccc(C2OCCO2)n1 -US20100183564A1,3,CC(C)n1ccc2c(NCCc3ccc(O)cc3)nc(Cl)nc21.OB(O)c1cncc(F)c1>>CC(C)n1ccc2c(NCCc3ccc(O)cc3)nc(-c3cncc(F)c3)nc21 -US20110294850A1,2,CC1(C)CN(Cc2ccccc2)c2ccc(O)cc21.CCCCCCN=C=O>>CCCCCCNC(=O)Oc1ccc2c(c1)C(C)(C)CN2Cc1ccccc1 -US20080269481A1,7,CC1=CCC(C(=O)O)OC1>>CC1CCC(C(=O)O)OC1 -US06458784B1,2,CC(C)(C)OC(=O)NCCC(=O)O.COC(=O)CC1Cc2ccc(N)cc2CN(C)C1=O>>COC(=O)CC1Cc2ccc(NC(=O)CCNC(=O)OC(C)(C)C)cc2CN(C)C1=O -US07879850B2,4,COc1ccc(C(=O)NNC(=O)c2ccc3nc(-c4c(C)cccc4C)[nH]c3c2)cc1>>COc1ccc(-c2nnc(-c3ccc4nc(-c5c(C)cccc5C)[nH]c4c3)o2)cc1 -US08242273B2,1,CC(C)N.Fc1ccc(C#Cc2ccnc(Cl)n2)cc1>>CC(C)Nc1nccc(C#Cc2ccc(F)cc2)n1 -US07132428B2,2,Cc1n[nH]c(-c2ccccc2)c1N.O=C(Cl)c1ccccc1>>Cc1n[nH]c(-c2ccccc2)c1NC(=O)c1ccccc1 -US20140206681A1,2,COC(=O)c1ccc(Br)cc1Cl.Nc1cc(C(F)(F)F)ccn1>>O=C(Nc1cc(C(F)(F)F)ccn1)c1ccc(Br)cc1Cl -US20110257208A1,1,Cc1cccc(C=O)c1C.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>Cc1cccc(CN2Cc3ncnc(Nc4cnc5ccccc5c4)c3C2)c1C -US20130012544A1,1,COc1ccc(C2=NN(C3CCN(C(=O)CCl)CC3)C(=O)C2(C)C)cc1OC.O=C1CCCC(=O)N1>>COc1ccc(C2=NN(C3CCN(C(=O)CN4C(=O)CCCC4=O)CC3)C(=O)C2(C)C)cc1OC -US07238714B2,1,COC(=O)c1ccc(F)c(Br)c1.Oc1cccc(F)c1>>COC(=O)c1ccc(Oc2cccc(F)c2)c(Br)c1 -US20140100373A1,3,CCOC(=O)CBr.CNC(=O)c1ccc2cc(C(=O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2c1>>CCOC(=O)C[C@](O)(c1ccc2cc(C(=O)NC)ccc2c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US06326359B1,2,COCCS(=O)(=O)Cl.COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN)nc32)[C@H](O)[C@@H]1O>>COCCS(=O)(=O)NCc1nc(NCC(c2ccccc2)c2ccccc2)c2ncn([C@@H]3O[C@H](COC)[C@@H](O)[C@H]3O)c2n1 -US07737166B2,6,COC(=O)c1cc(-c2ccccc2)c(Br)c2cc(C(C)(C)C)oc12>>CC(C)(C)c1cc2c(Br)c(-c3ccccc3)cc(C(=O)O)c2o1 -US20110130415A1,1,CI.O=c1[nH]nnn1-c1cc(Cl)cc([N+](=O)[O-])c1>>Cn1nnn(-c2cc(Cl)cc([N+](=O)[O-])c2)c1=O -US20110105509A1,8,O=C1CCC(CO)=NN1CCCC(F)(F)F>>O=CC1=NN(CCCC(F)(F)F)C(=O)CC1 -US04024147,1,Cc1ccccc1C(=O)NC1CCN(CCCCl)CC1.c1ccc(CNc2ccccn2)cc1>>Cc1ccccc1C(=O)NC1CCN(CCCN(Cc2ccccc2)c2ccccn2)CC1 -US04331683,2,CCCCCCCCN.O=C(O)C=Cc1ccccc1[N+](=O)[O-]>>CCCCCCCCNC(=O)C=Cc1ccccc1[N+](=O)[O-] -US08916599B2,2,Nc1ccccc1C(F)(F)F.O=C(O)c1ccc2[nH]c(Nc3c(Cl)cccc3Cl)nc2c1>>O=C(Nc1ccccc1C(F)(F)F)c1ccc2[nH]c(Nc3c(Cl)cccc3Cl)nc2c1 -US06716878B1,6,CC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C>>CC(=O)[C@@H](N)C(C)(C)C -US05256675,6,CC(=O)Nc1ncc(Sc2ccc(F)cc2F)s1>>Nc1ncc(Sc2ccc(F)cc2F)s1 -US20150210699A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@@H]1CCCNC1 -US20100041892A1,1,CC(=O)c1ccc(O)cc1O.COCCO>>COCCOc1ccc(C(C)=O)c(O)c1 -US07816387B2,8,COC(=O)c1cc(CO)cc(N(C)S(C)(=O)=O)c1>>COC(=O)c1cc(C=O)cc(N(C)S(C)(=O)=O)c1 -US08268820B2,1,CC(c1ccc(O)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.COC(=O)c1cnc(Cl)cn1>>COC(=O)c1cnc(Oc2ccc(C(C)C(O)(c3ccc4c(c3)N(C)C(=O)CO4)C(F)(F)F)c(Cl)c2)cn1 -US05541229,6,CCCCc1nc2ccc(N(Cc3ccccc3)C(=O)OCC)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2ccc(N(Cc3ccccc3)C(=O)OCC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US08729274B2,7,C=C(C)c1ccc2c(c1Cl)CC[C@]1(C)CN(Cc3ccccc3)C[C@H]21>>CC(C)c1ccc2c(c1Cl)CC[C@]1(C)CN(Cc3ccccc3)C[C@H]21 -US07629477B2,7,CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)/C=C\c1cccc(C#N)c1>>CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)CCc1cccc(C#N)c1 -US08975254B2,7,CC(=O)c1cc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3C)n2)[nH]n1>>Cc1c(-c2ccn(C[C@H](C)NC(=O)c3cc(C(C)O)n[nH]3)n2)ccc(C#N)c1Cl -US20130085164A1,6,CCOC(=O)c1ccc(-c2ccc(C(CC)n3ccnc3)nc2)cc1>>CCC(c1ccc(-c2ccc(C(=O)O)cc2)cn1)n1ccnc1 -US08796296B2,2,CNC.COc1c([N+](=O)[O-])cc2oc(C(=O)O)cc2c1Cl>>COc1c([N+](=O)[O-])cc2oc(C(=O)N(C)C)cc2c1Cl -US20140088078A1,6,CC(C)(C)OC(=O)NC(NC(=O)OC(C)(C)C)C1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)NC(NC(=O)OC(C)(C)C)C1CNC1 -US05646171,7,CCOC(=O)c1c(C(C)(C)O)nc(COC(C)=O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)c1c(C(C)(C)O)nc(CO)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20100056497A1,2,COCCCOc1cc(C(=O)N(C(C)C)[C@@H]2CC[C@@H](CCNC3CC3)N(C(=O)OC(C)(C)C)C2)ccc1OC.O=C(O)CC1CCCCC1>>COCCCOc1cc(C(=O)N(C(C)C)[C@@H]2CC[C@H](CCN(C(=O)CC3CCCCC3)C3CC3)N(C(=O)OC(C)(C)C)C2)ccc1OC -US20090136472A1,6,CCOC(=O)c1ccc(N=C2NC(=O)C(Cc3cccc(C(F)(F)F)c3)S2)cc1>>O=C(O)c1ccc(N=C2NC(=O)C(Cc3cccc(C(F)(F)F)c3)S2)cc1 -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3cccc(OC)c3)cc2)cc1)Oc1ccc(C(C)C)cc1>>COc1cccc(-c2ccc(C(=O)NCCOc3ccc(CC(Oc4ccc(C(C)C)cc4)C(=O)O)cc3)cc2)c1 -US07989461B2,3,CNc1ncc2cc(B3OC(C)(C)C(C)(C)O3)c(=O)n(C)c2n1.Cc1ccc2c(Nc3cccc(C(F)(F)F)c3)nccc2c1I>>CNc1ncc2cc(-c3c(C)ccc4c(Nc5cccc(C(F)(F)F)c5)nccc34)c(=O)n(C)c2n1 -US04028344,2,CC(C)(C)N=NC1(N=C=O)CCCCC1.CNN>>CN(N)C(=O)NC1(N=NC(C)(C)C)CCCCC1 -US05932568,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.N[C@@H]1CCCCNC1=O>>O=C1NCCCC[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20040072818A1,7,O=C(Nc1ccc(F)cc1)N1CCN(c2ccnc3cc([N+](=O)[O-])ccc23)CC1>>Nc1ccc2c(N3CCN(C(=O)Nc4ccc(F)cc4)CC3)ccnc2c1 -US20040116471A1,1,CCOC(=O)c1cc(CBr)ccc1OC.c1ccc2c(C3CCNCC3)c[nH]c2c1>>CCOC(=O)c1cc(CN2CCC(c3c[nH]c4ccccc34)CC2)ccc1OC -US20060194837A1,1,CN.O=Cc1cccc(OCCCO)c1>>CNCc1cccc(OCCCO)c1 -US08263610B2,1,CCOC(=O)C(Br)c1ccccc1.COc1ccc(Cn2ncc3c4c(cnc32)CNCC4)cc1>>CCOC(=O)C(c1ccccc1)N1CCc2c(cnc3c2cnn3Cc2ccc(OC)cc2)C1 -US20020193367A1,1,CC(C)(C)OC(=O)Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-].CC(C)CN>>CC(C)CNc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1Cl -US20090048251A1,2,C1CCNC1.COC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cscn4)c3)c12>>C[C@@H](Oc1cccc2ncnc(Nc3ccc4c(cnn4Cc4cscn4)c3)c12)C(=O)N1CCCC1 -US04971993,6,CC[C@H](C)[C@H](NS(=O)(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CC[C@H](C)[C@H](NS(=O)(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)O -US08778937B2,4,Nc1cc([N+](=O)[O-])cc(Br)c1N.O=C(O)CF>>O=[N+]([O-])c1cc(Br)c2nc(CF)[nH]c2c1 -US20110263571A1,1,COC(=O)c1ccc(Br)cc1OC.C[C@@H]1COC(=O)N1>>COC(=O)c1ccc(N2C(=O)OC[C@H]2C)cc1OC -US07728005B2,7,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)N[C@H](CO)COCc1ccccc1 -US20020147198A1,2,Nc1ccc(Cl)cc1.Nc1cccnc1C(=O)O>>Nc1cccnc1C(=O)Nc1ccc(Cl)cc1 -US07592477B2,1,CC(C)(N)c1cccc(Cl)c1.CCCCCCc1ccc(C#Cc2ccc(C=O)cc2)cc1>>CCCCCCc1ccc(C#Cc2ccc(CNC(C)(C)c3cccc(Cl)c3)cc2)cc1 -US20070191385A1,3,CC(C)(C)c1ccc(B(O)O)cc1.O=C1CN(c2ccc(-n3cc(-c4ccc(Cl)cc4Cl)nc3Cc3ccc(Br)cc3)cc2)S(=O)(=O)N1>>CC(C)(C)c1ccc(-c2ccc(Cc3nc(-c4ccc(Cl)cc4Cl)cn3-c3ccc(N4CC(=O)NS4(=O)=O)cc3)cc2)cc1 -US08530520B2,9,CC(C)COC1=CC(=O)C(Cc2cccc(CCI)c2)C1.[N-]=[N+]=[N-]>>CC(C)COC1=CC(=O)C(Cc2cccc(CCN=[N+]=[N-])c2)C1 -US08183246B2,1,CCc1ccc(-c2c(-c3ccccc3F)oc3ncnc(Cl)c23)cc1.C[C@@H](O)CCCCC(=O)OC(C)(C)C>>CCc1ccc(-c2c(-c3ccccc3F)oc3ncnc(O[C@H](C)CCCCC(=O)OC(C)(C)C)c23)cc1 -US20070254882A1,6,CCOC(=O)CN(Cc1cccc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)c1)S(=O)(=O)N(CC)CC>>CCN(CC)S(=O)(=O)N(CC(=O)O)Cc1cccc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)c1 -US20070197621A1,4,CC(C)NN.CCC(=O)C(Cc1nccn1Cc1ccccc1)C(=O)CC>>CCc1nn(C(C)C)c(CC)c1Cc1nccn1Cc1ccccc1 -US05789436,1,CC(=O)Oc1c(C(C)(C)C)cc2c(c1C(C)(C)C)CC(C)(CI)S2.CC(=O)[O-]>>CC(=O)OCC1(C)Cc2c(cc(C(C)(C)C)c(OC(C)=O)c2C(C)(C)C)S1 -US04123432,2,COc1ccc(Cn2nnnc2C(=O)Cl)cc1.N#Cc1c(N)cccc1N1CCCCC1>>COc1ccc(Cn2nnnc2C(=O)Nc2cccc(N3CCCCC3)c2C#N)cc1 -US05326760,6,CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)OC(C)(C)C)C(=O)NCCN1CCOCC1>>CC(C)C[C@H](N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NCCN1CCOCC1 -US20110092547A1,1,COC(=O)c1ccc(O)cc1.O=[N+]([O-])c1ccc(Cl)nc1>>COC(=O)c1ccc(Oc2ccc([N+](=O)[O-])cn2)cc1 -US06777428B1,2,CN1CCC(C(=O)c2cccc(N)c2)CC1.O=C(Cl)c1c(F)cccc1F>>CN1CCC(C(=O)c2cccc(NC(=O)c3c(F)cccc3F)c2)CC1 -US20130045962A1,9,Cc1nc(Cl)c(F)c(N2CCN3CCOC[C@@H]3C2)n1.NN>>Cc1nc(NN)c(F)c(N2CCN3CCOC[C@@H]3C2)n1 -US20080076758A1,2,C1CNCCN1.CC(C)S(=O)(=O)Cl>>CC(C)S(=O)(=O)N1CCNCC1 -US20070208030A1,1,ClCCBr.Clc1ccc(N2CCNCC2)cc1Cl>>ClCCN1CCN(c2ccc(Cl)c(Cl)c2)CC1 -US08299267B2,3,CC(C)(C)OC(=O)NCc1cncc(Br)c1.OB(O)C1CC1>>CC(C)(C)OC(=O)NCc1cncc(C2CC2)c1 -US08536338B2,3,CN(C(=O)OC(C)(C)C)C(=O)c1c(-c2ccc(F)cc2)nn2ccc(Cl)c(F)c12.Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)O)cc1-c1ccn2nc(-c3ccc(F)cc3)c(C(=O)N(C)C(=O)OC(C)(C)C)c2c1F -US05545747,1,CCCCCC1CC(C(=O)O)C1.CCCCCCOc1ccc(-c2ccc(O)c(F)c2)cc1F>>CCCCCCOc1ccc(-c2ccc(OC(=O)C3CC(CCCCC)C3)c(F)c2)cc1F -US20040106653A1,6,COc1cccc(F)c1C=O>>O=Cc1c(O)cccc1F -US20140336108A1,1,Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCC=O)sc34)cc2F)c1.OC1CCNCC1>>Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCC(O)CC5)sc34)cc2F)c1 -US20090239860A1,1,BrCc1ccccc1.COC(=O)c1ccc(O)c(CN2CCOCC2)c1>>COC(=O)c1ccc(OCc2ccccc2)c(CN2CCOCC2)c1 -US20070105820A1,3,COc1ccc(CN2C(=O)C(=O)c3ccccc32)cc1.[Mg+]c1ccc2c(c1)OCCO2>>COc1ccc(CN2C(=O)C(O)(c3ccc4c(c3)OCCO4)c3ccccc32)cc1 -US20100184815A1,2,CC(C)(C)OC(=O)C(C)(C)Sc1ccc(C(=O)O)cc1.CCCc1nn(Cc2ccc(C(F)(F)F)cc2)cc1CO>>CCCc1nn(Cc2ccc(C(F)(F)F)cc2)cc1COC(=O)c1ccc(SC(C)(C)C(=O)OC(C)(C)C)cc1 -US20040121965A1,2,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](N)C(C)(C)C.CN[C@H](C(=O)O)C(C)(C)c1ccc(Cl)cc1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)(C)c1ccc(Cl)cc1)C(C)(C)C -US08067411B2,1,CCCCOc1nc(N)c2[nH]c(=O)n(CCCNCCCN3CCOCC3)c2n1.O=Cc1ccccc1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCN(CCCN3CCOCC3)Cc3ccccc3)c2n1 -US04957917,7,C[Si](C)(C)c1cc(C#CCCCCCCCCCCCO)co1>>C[Si](C)(C)c1cc(C=CCCCCCCCCCCCO)co1 -US20150141464A1,7,COC(=O)c1ccc(NCc2ccc(Br)cc2)c([N+](=O)[O-])c1>>COC(=O)c1ccc(NCc2ccc(Br)cc2)c(N)c1 -US20150018363A1,7,CCOC(=O)c1nc(C#N)cs1>>N#Cc1csc(CO)n1 -US20130096119A1,2,CCNC(=O)Nc1cc2cc(N)cc(C)c2cn1.COC(=O)c1cccc(C(=O)[O-])c1>>CCNC(=O)Nc1cc2cc(NC(=O)c3cccc(C(=O)OC)c3)cc(C)c2cn1 -US08778926B2,3,CC(C)(C)OC(=O)N1CCC(C2Cc3cc(Cl)ncc3O2)CC1.CC1(C)OB(c2ccc(CS(C)(=O)=O)cc2F)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(C2Cc3cc(-c4ccc(CS(C)(=O)=O)cc4F)ncc3O2)CC1 -US20070299093A1,2,CC(c1cccc(OCCCN)c1)N(C)C.O=C(O)CCCC[C@H]1CCSS1>>CC(c1cccc(OCCCNC(=O)CCCCC2CCSS2)c1)N(C)C -US03976657,2,Nc1ccc(-c2nc(-c3ccco3)no2)c(Cl)c1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1ccc(-c2nc(-c3ccco3)no2)c(Cl)c1)OCC(Cl)(Cl)Cl -US20130035310A1,2,Nc1ncns1.O=C(N1CCC(c2ccc(S(=O)(=O)Cl)cc2)CC1)C(F)(F)F>>O=C(N1CCC(c2ccc(S(=O)(=O)Nc3ncns3)cc2)CC1)C(F)(F)F -US07750155B2,1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.ICC12CCC(CC1)O2>>CC(C)(C)OC(=O)N[C@@H]1CCN(CC23CCC(CC2)O3)C1 -US20100016266A1,3,CC1(C)C(=O)N=C2C=CC(Br)=CN21.OB(O)c1cccc(Cl)c1>>CC1(C)C(=O)N=C2C=CC(c3cccc(Cl)c3)=CN21 -US07696210B2,1,CCCI.Cc1nc(C=O)c[nH]1>>CCCn1cc(C=O)nc1C -US06218381B1,1,ClCc1ccc2ccccc2n1.OCCc1ccc(O)cc1>>OCCc1ccc(OCc2ccc3ccccc3n2)cc1 -US08436008B2,3,CC(C)(C)OC(=O)N1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.CN1CCN(c2cc(N3CCc4ccc(Br)cc4C3)nc(N)n2)CC1>>CN1CCN(c2cc(N3CCc4ccc(-c5cnn(C6CCN(C(=O)OC(C)(C)C)CC6)c5)cc4C3)nc(N)n2)CC1 -US20140315917A1,1,Cc1nc(I)ccc1O.Clc1ccnc(Cl)c1>>Cc1nc(I)ccc1Oc1ccnc(Cl)c1 -US04227009,2,CC(Oc1ccc(Oc2ccc(Cl)cc2)cc1)C(=O)O.OCCCCCl>>CC(Oc1ccc(Oc2ccc(Cl)cc2)cc1)C(=O)OCCCCCl -US20030069284A1,1,O=Cc1ccccc1.O[C@H]1CCNC1>>O[C@H]1CCN(Cc2ccccc2)C1 -US05932571,1,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3n2CCO)CC1.N#CCBr>>CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3n2CCOCC#N)CC1 -US20010053851A1,2,Nc1nccs1.O=C(O)C(CC1CCCC1)c1ccc(C#Cc2ccccn2)cc1>>O=C(Nc1nccs1)C(CC1CCCC1)c1ccc(C#Cc2ccccn2)cc1 -US05885999,2,CC(C)(C)OC(=O)N[C@@H](COCc1ccc(Cl)c(Cl)c1)C(=O)O.O=c1[nH]c2ccccc2n1C1CCNCC1>>CC(C)(C)OC(=O)N[C@@H](COCc1ccc(Cl)c(Cl)c1)C(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 -US20070155727A1,6,COC(=O)c1ccc(CN(C)CCN(C)CC(=O)Nc2ccc(OCC(F)(F)C(F)(F)F)cc2)cc1>>CN(CCN(C)Cc1ccc(C(=O)O)cc1)CC(=O)Nc1ccc(OCC(F)(F)C(F)(F)F)cc1 -US20120059002A1,7,COC(OC)c1cc(C)c(C#N)c(C)c1>>COC(OC)c1cc(C)c(CN)c(C)c1 -US20070249624A1,3,CCCC[Sn](CCCC)(CCCC)c1cnccn1.COc1cnc(Br)c2[nH]cc(C(=O)C(=O)N3CCN(c4c(-c5ccccc5)c(=O)c4=O)CC3)c12>>COc1cnc(-c2cnccn2)c2[nH]cc(C(=O)C(=O)N3CCN(c4c(-c5ccccc5)c(=O)c4=O)CC3)c12 -US07160905B2,2,COc1cc(C(=O)O)cc(S(C)(=O)=O)c1.C[C@H](C[C@H](O)[C@@H](N)Cc1ccccc1)C(=O)NC1CC2CCC1C2>>COc1cc(C(=O)N[C@@H](Cc2ccccc2)[C@@H](O)C[C@@H](C)C(=O)NC2CC3CCC2C3)cc(S(C)(=O)=O)c1 -US20110152081A1,1,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1F.SCc1ccccc1>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1SCc1ccccc1 -US04956123,7,CC(CC(F)(F)C(F)(F)C(F)(F)F)(OC(=O)C(F)(F)C(F)(F)C(F)(F)F)c1ccccc1>>CC(O)(CC(F)(F)C(F)(F)C(F)(F)F)c1ccccc1 -US20130225552A1,1,CC1(C)C(=O)N(C2CCNCC2)c2nccnc21.Clc1nc2ccccc2s1>>CC1(C)C(=O)N(C2CCN(c3nc4ccccc4s3)CC2)c2nccnc21 -US20130296312A1,3,Nc1nc2cccc(Br)n2n1.O=S1(=O)CCN(Cc2ccc(B(O)O)cc2)CC1>>Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1 -US20120157494A1,2,C[C@H](CO)N1Cc2c(ccc(Cl)c2N)C1=O.O=C(Cl)CC12CC3CC(CC(C3)C1)C2>>C[C@H](CO)N1Cc2c(ccc(Cl)c2NC(=O)CC23CC4CC(CC(C4)C2)C3)C1=O -US20150239838A1,2,NC(=O)c1nn(CC(=O)O)c2ccccc12.O=C(Nc1cccc(-c2cc(F)c(F)cc2Cl)c1F)[C@@H]1C[C@@H](F)CN1>>NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3cc(F)c(F)cc3Cl)c2F)c2ccccc12 -US20140112945A1,6,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccc(C)cc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(C)cc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US07067534B1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.C[C@@H](CCl)COc1ccc(F)cc1>>CC(C)C(=O)Nc1cccc(C2CCN(C[C@H](C)COc3ccc(F)cc3)CC2)c1 -US20130150326A1,1,CC(=O)CCl.CCOC(=O)Cc1cccc(S)c1>>CCOC(=O)Cc1cccc(SCC(C)=O)c1 -US05919969,2,CCCCCCCCCCCCS(=O)(=O)c1ccc(N)c(Cl)c1.CCOC(=O)C(C(=O)OCC)N1C(=O)c2ccccc2C1=O>>CCCCCCCCCCCCS(=O)(=O)c1ccc(NC(=O)C(C(=O)OCC)N2C(=O)c3ccccc3C2=O)c(Cl)c1 -US04250183,2,CCOC(=O)[C@@H]1CCCN1.Cc1cccc(C)c1N(CCCC(=O)O)C(=O)c1ccc(Cl)cc1>>CCOC(=O)[C@@H]1CCCN1C(=O)CCCN(C(=O)c1ccc(Cl)cc1)c1c(C)cccc1C -US20080255105A1,2,CCOC(=O)c1ccc(-c2cc(N)ccc2Cl)cc1.O=C=NC1CCCCC1>>CCOC(=O)c1ccc(-c2cc(NC(=O)NC3CCCCC3)ccc2Cl)cc1 -US05646173,4,CCC1(CC)c2ccc(OC)cc2C(=O)C1CC=O.C[C@@H](O)CN>>CCC1(CC)c2ccc(OC)cc2-c2c1ccn2C[C@@H](C)O -US05578604,1,C=Cc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1.NC1C=CCC2CNCC12>>C=Cc1c(F)c(N2CC3CC=CC(N)C3C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1 -US20090325936A1,3,CCOC(=O)c1nc(Br)c2ccccn12.OB(O)c1ccc(F)cc1>>CCOC(=O)c1nc(-c2ccc(F)cc2)c2ccccn12 -US20050004187A1,3,CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)c(Br)cn2[Si](C)(C)C(C)(C)C.CCCCI>>CCCCc1cn([Si](C)(C)C(C)(C)C)c2ccc(O[Si](C)(C)C(C)(C)C)cc12 -US08609847B2,6,CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(c2)CCC(=O)N3c2ccc(F)cc2)CC1>>O=C1CCc2cc(OC3CCNCC3)ccc2N1c1ccc(F)cc1 -US20100280030A1,7,CC(c1cccc([N+](=O)[O-])c1)n1c(=O)oc2cc(F)c(F)cc21>>CC(c1cccc(N)c1)n1c(=O)oc2cc(F)c(F)cc21 -US20070191454A1,3,C#C[Si](C)(C)C.O=[N+]([O-])c1ccccc1Br>>C[Si](C)(C)C#Cc1ccccc1[N+](=O)[O-] -US20040209943A1,2,CCC(C)C(C(=O)Cl)c1ccccc1.N#Cc1c(N)sc2c1CCC2>>CCC(C)C(C(=O)Nc1sc2c(c1C#N)CCC2)c1ccccc1 -US20140135318A1,2,CCCCN(CCC(=O)O)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Cl.NC(CO)(CO)CO>>CCCCN(CCC(=O)NC(CO)(CO)CO)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Cl -US20120010301A1,7,CCCCCC1CC2C=CC(C2)C1=O>>CCCCCC1CC2CCC(C2)C1=O -US20080146612A1,2,COC(=O)c1ncccc1-c1ccc(Cl)c(C(=O)O)c1.NCC1(O)CCCCCC1>>COC(=O)c1ncccc1-c1ccc(Cl)c(C(=O)NCC2(O)CCCCCC2)c1 -US20070219210A1,2,CCNC.COc1ccc(-n2nc(C(=O)O)cc2-c2ccc(OCc3ccccc3)cn2)cn1>>CCN(C)C(=O)c1cc(-c2ccc(OCc3ccccc3)cn2)n(-c2ccc(OC)nc2)n1 -US08034812B2,1,CNC(=O)c1cn2nc(I)ccc2n1.Nc1cccc(O)c1>>CNC(=O)c1cn2nc(Oc3cccc(N)c3)ccc2n1 -US20060247238A1,1,Nc1ccc(-n2ccccc2=O)cc1.O=C(N[C@@H]1CCN(C(=O)CBr)C1)c1ccc(Cl)s1>>O=C(N[C@@H]1CCN(C(=O)CNc2ccc(-n3ccccc3=O)cc2)C1)c1ccc(Cl)s1 -US20130109715A1,2,C=C(C(=O)O)C(F)(F)F.CNOC>>C=C(C(=O)N(C)OC)C(F)(F)F -US05877190,1,COC(CBr)OC.COc1cc(Br)cc(C=O)c1O>>COc1cc(Br)cc(C=O)c1OCC(OC)OC -US20090221555A1,1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.CN1C(=O)CCC(C)(C)c2cc(N)ccc21>>CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2)C(C)(C)CCC(=O)N3C)ncc1Cl -US20070123515A1,1,BrCc1ccccc1.CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCOCC4)cc3c2)CC1>>CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCOCC2)n3Cc2ccccc2)CC1 -US08642585B2,3,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1cccc(-c2cc(C)c(Br)c(C)c2)n1>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(-c6cccc(C)n6)cc5C)ccc(F)c43)ccc21 -US20100298221A1,6,CC(C)(C)OC(=O)c1cc(F)c(-c2cccc(C(F)(F)F)c2)nc1Oc1ccccc1Cl>>O=C(O)c1cc(F)c(-c2cccc(C(F)(F)F)c2)nc1Oc1ccccc1Cl -US20090143439A1,2,CCOC(=O)c1cc(N)nc(N)c1.CN>>CNC(=O)c1cc(N)nc(N)c1 -US20030134402A1,7,COC(=O)CC(=O)CBr>>COC(=O)C[C@H](O)CBr -US20150072980A1,7,COc1ccc2c(c1Cl)C/C(=C\c1ccc(SC(F)(F)F)cc1)C2=O>>COc1ccc2c(c1Cl)CC(Cc1ccc(SC(F)(F)F)cc1)C2=O -US06413947B1,2,CN(Cc1ccc(N)cc1)C1CCOCC1.CN1CCN(c2ccc(-c3ccc4c(c3)C=C(C(=O)O)CCO4)cc2)CC1>>CN1CCN(c2ccc(-c3ccc4c(c3)C=C(C(=O)Nc3ccc(CN(C)C5CCOCC5)cc3)CCO4)cc2)CC1 -US07790763B2,1,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(O)cc1>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2)CC1 -US20090149483A1,1,CCOC(=O)CNC(=C(C#N)C#N)N1CCC[C@@H](NC(=O)OC(C)(C)C)C1.Clc1ccccc1CBr>>CCOC(=O)CN(Cc1ccccc1Cl)C(=C(C#N)C#N)N1CCC[C@@H](NC(=O)OC(C)(C)C)C1 -US20150119405A1,2,C#CC(=O)O.CCOc1ccc(F)c(-c2ccc3nc(N[C@@H]4CCC[C@@H]4N)ncc3c2)c1Cl>>C#CC(=O)N[C@H]1CCC[C@H]1Nc1ncc2cc(-c3c(F)ccc(OCC)c3Cl)ccc2n1 -US20030114442A1,1,O=C(Cc1ccccc1)N1CCNCC1.O=C(NCc1ccccc1)C1(CCCCBr)c2ccccc2-c2ccccc21>>O=C(Cc1ccccc1)N1CCN(CCCCC2(C(=O)NCc3ccccc3)c3ccccc3-c3ccccc32)CC1 -US20080200431A1,2,CC(C)N.Cn1nc(N2CCC(CN3C(=O)CN(S(=O)(=O)c4ccc5c(Cl)c[nH]c5c4)CC3C(=O)O)CC2)ccc1=O>>CC(C)NC(=O)[C@@H]1CN(S(=O)(=O)c2ccc3c(Cl)c[nH]c3c2)CC(=O)N1CC1CCN(c2ccc(=O)n(C)n2)CC1 -US05443754,1,BrCCCCCCCCC1CC1.CCCCCCCCOc1ccc(-c2ncc(O)cn2)cn1>>CCCCCCCCOc1ccc(-c2ncc(OCCCCCCCCC3CC3)cn2)cn1 -US04954518,7,COc1ccc(O)c([N+](=O)[O-])c1>>COc1ccc(O)c(N)c1 -US05021412,7,N#Cc1ccc(OCC(F)(F)F)c(F)c1>>NCc1ccc(OCC(F)(F)F)c(F)c1 -US06825191B2,1,COC(=O)c1cccc(CBr)c1.O=C1CN(C(=O)c2ccc(Cl)cc2)Cc2ccccc2N1>>COC(=O)c1cccc(CN2C(=O)CN(C(=O)c3ccc(Cl)cc3)Cc3ccccc32)c1 -US09050345B2,3,CC(=O)Nc1cncc(Cl)n1.Clc1nc(NCc2ccccn2)c2c(-c3ccccc3)ccn2n1>>CC(=O)Nc1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)n1 -US20150252008A1,3,Nc1cnc(Br)cn1.OB(O)c1ccc(Cl)c(OCc2ccccc2)c1F>>Nc1cnc(-c2ccc(Cl)c(OCc3ccccc3)c2F)cn1 -US20020156081A1,3,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)OC(C)(C)C.Nc1ncnc2c1c(I)nn2C1CCN(C(=O)OCc2ccccc2)CC1>>COc1cc(-c2nn(C3CCN(C(=O)OCc4ccccc4)CC3)c3ncnc(N)c23)ccc1NC(=O)OC(C)(C)C -US08188098B2,8,CC(C)c1noc(N2CCC(O)CC2)n1>>CC(C)c1noc(N2CCC(=O)CC2)n1 -US20090054428A1,1,COc1cnc(Cl)c(N(C)c2ccnc(Cl)n2)c1.Nc1cc(N2CCOCC2)cc(N2CCOCC2)c1>>COc1cnc(Cl)c(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 -US20140163033A1,2,COC(=O)c1cccn1NC(=O)[C@H](C)NC(=O)OC(C)(C)C.NC1CC1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)Nn1cccc1C(=O)NC1CC1 -US04925875,7,O=[N+]([O-])c1cc(Cl)c(OC(F)(F)C(F)(F)F)cc1Cl>>Nc1cc(Cl)c(OC(F)(F)C(F)(F)F)cc1Cl -US08288549B2,1,NC(Cc1cccs1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1NC(Cc1cccs1)C(=O)O -US06544985B2,2,CCOC(=O)CC(=O)c1cccc(-n2ccnn2)c1.CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl>>CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3ccnn3)c2)cc1Cl -US08263606B2,1,CC(C)c1cc(CO)on1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCO3>>CC(C)c1cc(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)on1 -US20050277670A1,2,CC(CCN)N1CCC(C(Oc2ccccn2)c2ccc(C(F)(F)F)cc2)CC1.Cc1cc(-c2ccncc2)cc(C)c1C(=O)O>>Cc1cc(-c2ccncc2)cc(C)c1C(=O)NCCC(C)N1CCC(C(Oc2ccccn2)c2ccc(C(F)(F)F)cc2)CC1 -US05037849,9,N.O=C(CCl)N[C@@H]1CC[C@@H](O)CC1>>NCC(=O)N[C@@H]1CC[C@@H](O)CC1 -US20130184317A1,2,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.Nc1nncs1>>CC(=O)Nc1ccc(S(=O)(=O)Nc2nncs2)cc1 -US20100266504A1,6,CC(C)CNc1ccc2c(n1)CCN(Cc1ccccc1)C2>>CC(C)CNc1ccc2c(n1)CCNC2 -US20050143421A1,3,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=O)CC3)c(F)c2)C(=O)O1.Nc1ccccc1S.[C-]#N>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(C#N)(Nc4ccccc4S)CC3)c(F)c2)C(=O)O1 -US06455521B1,2,Cc1cc(C(=O)O)c(Br)s1.Nc1cc([N+](=O)[O-])ccc1O>>Cc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2O)c(Br)s1 -US20150126537A1,2,CCOP(=O)(CC(=O)O)OCC.Nc1cc2c(Nc3ccc(Oc4ccccc4)cc3)ncnc2cc1O[C@H]1CCOC1>>CCOP(=O)(CC(=O)Nc1cc2c(Nc3ccc(Oc4ccccc4)cc3)ncnc2cc1O[C@H]1CCOC1)OCC -US07384960B2,2,NN1CCC2(CCCC2)CC1.O=C(O)c1nn(-c2ccc(Cl)cc2Cl)c2c1SCc1cc(Cl)ccc1-2>>O=C(NN1CCC2(CCCC2)CC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1SCc1cc(Cl)ccc1-2 -US20150064196A1,1,BrCc1ccc(Br)cc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(Br)cc2)CC1 -US20120088750A1,6,CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(Br)c2s1>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)cc(Br)c2s1 -US08399681B2,4,N#CC1CCN(C(=O)OCc2ccccc2)CC1.[N-]=[N+]=[N-]>>O=C(OCc1ccccc1)N1CCC(c2nnn[nH]2)CC1 -US07812040B2,1,C1CCNC1.COc1cc(O)ccc1C=O>>COc1cc(O)ccc1CN1CCCC1 -US20040162303A1,8,COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(C)(=O)=O)CC2O)nc1N>>COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(C)(=O)=O)CC2=O)nc1N -US07910740B2,4,COc1cc(NC(N)=S)ccc1-n1cnc(C)c1.O=C(CBr)c1ccc(Cl)cc1Cl>>COc1cc(Nc2nc(-c3ccc(Cl)cc3Cl)cs2)ccc1-n1cnc(C)c1 -US04735959,8,CC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(CO)cc1>>CC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(C=O)cc1 -US04952598,1,CC(C)C1(c2ccccc2OCCCCBr)C(=O)N(C)c2ccccc21.COc1cc(CN2CCNCC2)cc(OC)c1OC>>COc1cc(CN2CCN(CCCCOc3ccccc3C3(C(C)C)C(=O)N(C)c4ccccc43)CC2)cc(OC)c1OC -US20050222213A1,10,CCOC(=O)C(C)c1cccc(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>CCOC(=O)C(C)(Br)c1cccc(C(F)(F)F)c1 -US20060063940A1,1,CN1CCCC(COc2ccc(N)cc2)C1.Cc1cccc2c1C(=CO)C(=O)N2>>Cc1cccc2c1C(=CNc1ccc(OCC3CCCN(C)C3)cc1)C(=O)N2 -US20040192688A1,1,ClCCOc1ccc2ccccc2c1.NC1CCCCC1>>c1ccc2cc(OCCNC3CCCCC3)ccc2c1 -US20130040930A1,1,Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(Br)cc2C#N)CC1.O=S1(=O)CCCN1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2ccc(N3CCCS3(=O)=O)cc2C#N)CC1 -US20150175619A1,6,CCOC(=O)C1C2CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CC21>>CC(C)(C)[Si](OC1CC2C(C1)C2C(=O)O)(c1ccccc1)c1ccccc1 -US20150065705A1,1,CC(C)(C)OC(=O)N1CC(O)C1.Fc1ccc(CBr)cc1>>CC(C)(C)OC(=O)N1CC(OCc2ccc(F)cc2)C1 -US20050090541A1,3,CC(=O)c1ccc[nH]1.COc1ccc2c(c1)CC(=O)N2>>COc1ccc2c(c1)C(=C(C)c1ccc[nH]1)C(=O)N2 -US20140066455A1,2,COC(=O)c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)s1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)s3)[nH]n2)cc(OC)c1 -US05153201,1,CN(C)CCCl.COc1cccc(C=Cc2nc3c(s2)NCCC3)c1OC>>COc1cccc(C=Cc2nc3c(s2)N(CCN(C)C)CCC3)c1OC -US20150105391A1,1,Cc1cc(N2CCC(O)CC2)cc(C)c1-c1csc(NC(=O)c2ccncc2)n1.[N-]=[N+]=NCCOCCOCCOCCI>>Cc1cc(N2CCC(OCCOCCOCCOCCN=[N+]=[N-])CC2)cc(C)c1-c1csc(NC(=O)c2ccncc2)n1 -US20030087843A1,1,BrCc1ccccc1.CSc1ccc(Cc2c(C(F)(F)F)[nH][nH]c2=O)cc1>>CSc1ccc(Cc2c(C(F)(F)F)n(Cc3ccccc3)[nH]c2=O)cc1 -US20120058988A1,3,COC(=O)c1cc(Br)nc(Br)c1N.O=S(=O)(c1ccc(B(O)O)cc1)N1CCOCC1>>COC(=O)c1cc(Br)nc(-c2ccc(S(=O)(=O)N3CCOCC3)cc2)c1N -US20080269200A1,2,CC(=O)Cl.NC(=O)c1cc(-c2ccccc2)cc2c(C3CCNCC3)c[nH]c12>>CC(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccccc4)cc23)CC1 -US07005444B2,1,Cc1cc(C)c2c(N)n[nH]c2n1.O=C1Nc2ccccc2/C1=C/O>>Cc1cc(C)c2c(NC=C3C(=O)Nc4ccccc43)n[nH]c2n1 -US20070249670A1,6,COC(=O)C1(NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(C)cc(C)cc2C)CCNCC1>>Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC2(C(=O)O)CCNCC2)c(C)c1 -US20140100154A1,2,C#CCOc1cc(OC)cc(OC)c1S(=O)(=O)Cl.CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@](C)(O)CO>>C#CCOc1cc(OC)cc(OC)c1S(=O)(=O)OCC(C)(O)C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1 -US08058045B2,6,COC/C=C/c1cnc(Nc2cnc(C#N)cn2)cc1NCC1CCN(C(=O)OC(C)(C)C)CC1>>COC/C=C/c1cnc(Nc2cnc(C#N)cn2)cc1NCC1CCNCC1 -US20070112016A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.Nc1cc(OCc2ccccc2)ccc1Br>>CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc(OCc3ccccc3)ccc2Br)CC1 -US06500853B1,3,O=C(O)Cc1cn(CC2CC2)c2ccc(Br)cc12.OB(O)c1cccs1>>O=C(O)Cc1cn(CC2CC2)c2ccc(-c3cccs3)cc12 -US07429583B2,4,CC(C)(CCNc1ccc(C(F)(F)F)cc1N)NC(=O)OC(C)(C)C.O=C(n1ccnc1)n1ccnc1>>CC(C)(CCn1c(=O)[nH]c2cc(C(F)(F)F)ccc21)NC(=O)OC(C)(C)C -US20050010031A1,6,CCC1CN(C(Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)C(Cc1ccc(F)cc1)NC(=O)OC(C)(C)C>>CCC1CN(C(Cc2ccc3ccccc3c2)C(=O)NC)CCN1C(=O)C(N)Cc1ccc(F)cc1 -US07217717B2,6,COc1cc2ncnc(Nc3ccccc3)c2cc1OC(C)=O>>COc1cc2ncnc(Nc3ccccc3)c2cc1O -US07192950B2,2,COc1ccc(CC2c3cc(OC)c(OC)cc3CCCN2C(C(=O)O)c2ccccc2)cc1OC.CSCCN>>COc1ccc(CC2c3cc(OC)c(OC)cc3CCCN2C(C(=O)NCCSC)c2ccccc2)cc1OC -US20140371220A1,1,Clc1ccc2c(c1)CCN2.Cn1cc(-c2ccc(N3CCC(=O)CC3)nn2)cn1>>Cn1cc(-c2ccc(N3CCC(N4CCc5cc(Cl)ccc54)CC3)nn2)cn1 -US20140303143A1,1,CC(O)c1ccccc1.O=c1[nH]c2ccc([N+](=O)[O-])cc2o1>>CC(c1ccccc1)n1c(=O)oc2cc([N+](=O)[O-])ccc21 -US20100152192A1,3,CCOC(=O)c1c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)nc2sccn12.COc1cccc(C=O)c1OCC(C)C>>CCOC(=O)c1c(/C=C/c2cccc(OC)c2OCC(C)C)nc2sccn12 -US08557849B2,2,CC(C)(C)C(=O)Cl.Nc1cccc(Br)n1>>CC(C)(C)C(=O)Nc1cccc(Br)n1 -US04012389,1,CN(C)CCCl.Clc1ccc(CN2CCNCC2c2ccccc2)cc1Cl>>CN(C)CCN1CCN(Cc2ccc(Cl)c(Cl)c2)C(c2ccccc2)C1 -US20140249137A1,6,CC(C)(C)[Si](C)(C)OC(C(=O)O)c1ccc(-c2ncc(Cl)c(Nc3cc(C4CC4)[nH]n3)n2)s1>>O=C(O)C(O)c1ccc(-c2ncc(Cl)c(Nc3cc(C4CC4)[nH]n3)n2)s1 -US20150018363A1,1,Cn1c(C2CC2)nc2ccc(-n3ccc(Br)cc3=O)cc21.OCc1csc(Br)n1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4csc(Br)n4)cc3=O)cc21 -US20100093748A1,6,CC(C)(C)OC(=O)N1C(=O)n2c(nc3c(OCc4ccccc4)cccc32)C12CCN(c1ncnc3c1ccn3C(=O)OC(C)(C)C)CC2>>CC(C)(C)OC(=O)N1C(=O)n2c(nc3c(O)cccc32)C12CCN(c1ncnc3c1ccn3C(=O)OC(C)(C)C)CC2 -US20070142270A1,1,Cc1ncc(CNC(=O)c2ccc(-c3ccccc3S(=O)(=O)NC(C)(C)C)cc2)c(CO)c1O.N#Cc1cccc(CBr)c1>>Cc1ncc(CNC(=O)c2ccc(-c3ccccc3S(=O)(=O)NC(C)(C)C)cc2)c(CO)c1OCc1cccc(C#N)c1 -US08034812B2,1,Nc1cccc(O)c1.O=C(CC1CC1)Nc1cn2nc(I)ccc2n1>>Nc1cccc(Oc2ccc3nc(NC(=O)CC4CC4)cn3n2)c1 -US20130217664A1,1,CCc1cc(-c2cccs2)ncc1Nc1cc2c(cn1)ncn2C.CI>>CCc1cc(-c2cccs2)ncc1N(C)c1cc2c(cn1)ncn2C -US20090264336A1,6,COC(=O)c1cc(OCc2ccccc2)cc(O[C@@H](C)COC(F)F)c1>>COC(=O)c1cc(O)cc(O[C@@H](C)COC(F)F)c1 -US04191762,6,CCOC(=O)C(=O)c1csc(NC=O)n1>>O=CNc1nc(C(=O)C(=O)O)cs1 -US04900751,1,CI.O=S(c1nc2ccccc2[nH]1)c1ccccc1-c1ccccn1>>Cn1c(S(=O)c2ccccc2-c2ccccn2)nc2ccccc21 -US08933104B2,8,COC(=O)c1ccc(C(O)CC(C)C)nc1>>COC(=O)c1ccc(C(=O)CC(C)C)nc1 -US20150191416A1,2,CCCCC/C=C\C/C=C\CCCCCCCCO.CS(=O)(=O)Cl>>CCCCC/C=C\C/C=C\CCCCCCCCOS(C)(=O)=O -US20090163512A1,2,COCCS(N)(=O)=O.Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OC(C)(C)C(=O)O)C12C(=O)Nc1cc(Cl)ccc12>>COCCS(=O)(=O)NC(=O)C(C)(C)Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12 -US05854236,7,Cc1cc(C(=O)N2Cc3ccccc3Cc3ccccc32)ccc1[N+](=O)[O-]>>Cc1cc(C(=O)N2Cc3ccccc3Cc3ccccc32)ccc1N -US20030134891A1,3,C=CCOC(=O)[C@H]1CCCN1C(=O)CCCCC(=O)N1CCC[C@@H]1C(=O)OCC=C>>O=C1OCC=CCOC(=O)[C@H]2CCCN2C(=O)CCCCC(=O)N2CCC[C@H]12 -US05750531,1,CC1NCCc2ccsc21.Cc1cc(Cl)nc(Cl)n1>>Cc1cc(N2CCc3ccsc3C2C)nc(Cl)n1 -US20080262020A1,1,CCOCc1cc(-c2ccc3c(c2)c2cc(-c4ccc(F)cc4)c(=O)n(C)c2n3C)n[nH]1.CI>>CCOCc1cc(-c2ccc3c(c2)c2cc(-c4ccc(F)cc4)c(=O)n(C)c2n3C)nn1C -US20080177077A1,6,COC(=O)c1ccc(C)c(-n2c(C)cc(O)c(Br)c2=O)c1>>Cc1ccc(C(=O)O)cc1-n1c(C)cc(O)c(Br)c1=O -US20100227834A1,2,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.O=c1[nH]c(=O)n([C@H]2C[C@H](Cl)[C@@H](CO)O2)cc1/C=C/Br>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OC[C@H]1O[C@@H](n2cc(/C=C/Br)c(=O)[nH]c2=O)C[C@@H]1Cl -US20150148340A1,6,CCOC(=O)c1cn(-c2ccc3c(c2)OCC(=O)N3C)c(=O)n(Cc2cccc([N+](=O)[O-])c2C)c1=O>>Cc1c(Cn2c(=O)c(C(=O)O)cn(-c3ccc4c(c3)OCC(=O)N4C)c2=O)cccc1[N+](=O)[O-] -US20050043353A1,2,O=C(Cl)CCl.OC12CC3CC(CC(C3)C1)C2>>O=C(CCl)OC12CC3CC(CC(C3)C1)C2 -US20100160255A1,2,CCN1C(=O)SC2(CCCN(C3CCN(C(=O)c4c(N)sc5c4CCCC5=O)CC3)C2)C1=O.CCN=C=O>>CCNC(=O)Nc1sc2c(c1C(=O)N1CCC(N3CCCC4(C3)SC(=O)N(CC)C4=O)CC1)CCCC2=O -US20120302566A1,1,COC(=O)C[C@@H]1COc2cc(O)ccc21.O[C@H]1CCc2cc(Cl)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4cc(Cl)ccc43)ccc21 -US05891889,6,Cc1cccc(CC2(C(=O)OCc3ccccc3)CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1cccc(CC2(C(=O)O)CCN(C(=O)OC(C)(C)C)CC2)c1 -US07572794B2,1,Cn1cc2ccc(NC(=O)c3c(F)cccc3NCc3ccnc(Br)c3)cc2n1.NC(=O)N1CCOCC1>>Cn1cc2ccc(NC(=O)c3c(F)cccc3NCc3ccnc(NC(=O)N4CCOCC4)c3)cc2n1 -US20070054884A1,1,COc1cc(C)ccc1O.N#Cc1ccccc1F>>COc1cc(C)ccc1Oc1ccccc1C#N -US20120027780A1,2,CNc1ccc(C(=O)O)cc1[N+](=O)[O-].COC(=O)CCNc1ccccc1>>CNc1ccc(C(=O)N(CCC(=O)OC)c2ccccc2)cc1[N+](=O)[O-] -US20150051225A1,1,COc1ccccc1-c1nc(C2CC(C)(C)OC(C)(C)C2)c[nH]1.N#Cc1ccc(CBr)cc1>>COc1ccccc1-c1nc(C2CC(C)(C)OC(C)(C)C2)cn1Cc1ccc(C#N)cc1 -US20100022515A1,1,CC(CCC1CCN(C(=O)OC(C)C)CC1)Nc1ccc2c(c1)CCN(S(C)(=O)=O)C2.CI>>CC(C)OC(=O)N1CCC(CCC(C)N(C)c2ccc3c(c2)CCN(S(C)(=O)=O)C3)CC1 -US20030203888A1,6,CC(=O)Nc1ccc(-c2c3nc(c(-c4cccnc4)c4ccc([nH]4)c(-c4cccnc4)c4nc(c(-c5cccnc5)c5ccc2[nH]5)C=C4)C=C3)cc1>>Nc1ccc(-c2c3nc(c(-c4cccnc4)c4ccc([nH]4)c(-c4cccnc4)c4nc(c(-c5cccnc5)c5ccc2[nH]5)C=C4)C=C3)cc1 -US04665090,7,CC(=O)CCCc1cccs1>>CC(O)CCCc1cccs1 -US20090023704A1,6,CCc1nc2c(c(=O)n(Cc3ccc(Cl)cc3)c(=O)n2CC(=O)OC)n1C>>CCc1nc2c(c(=O)n(Cc3ccc(Cl)cc3)c(=O)n2CC(=O)O)n1C -US20150259367A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1Nc2ccccc2C12CNC2>>CC(C)(C)OC(=O)N1CC2(C1)C(=O)Nc1ccccc12 -US20110269244A1,6,CCOC(=O)c1ccc2[nH]c(-c3n[nH]c(C)c3C(=O)OCc3ccccc3)nc2c1>>CCOC(=O)c1ccc2[nH]c(-c3n[nH]c(C)c3C(=O)O)nc2c1 -US20130131018A1,7,CCOC(C/N=C/c1cccc(OC)c1OC)OCC>>CCOC(CNCc1cccc(OC)c1OC)OCC -US07030141B2,3,CC(C)(C)OC(=O)N1CCCC1C(=O)Nc1ccc(Br)cc1Cl.CSc1ccccc1B(O)O>>CSc1ccccc1-c1ccc(NC(=O)C2CCCN2C(=O)OC(C)(C)C)c(Cl)c1 -US20150087663A1,7,Cc1ccccc1NC(=O)c1c(Cl)cccc1[N+](=O)[O-]>>Cc1ccccc1NC(=O)c1c(N)cccc1Cl -US07470723B2,3,CCOc1cc([Mg+])ccc1OC.COc1ccc(C=O)cc1[N+](=O)[O-]>>CCOc1cc(C(O)c2ccc(OC)c([N+](=O)[O-])c2)ccc1OC -US20130196960A1,3,Cc1cc2ccsc2n1CCN1CCOCC1.O=C(Cl)c1cccc(Cl)c1Cl>>Cc1c(C(=O)c2cccc(Cl)c2Cl)c2ccsc2n1CCN1CCOCC1 -US04886810,1,Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1.O=C(N[C@@H]1CNC[C@@H]1CF)C(F)(F)F>>Nc1c(F)c(N2C[C@@H](NC(=O)C(F)(F)F)[C@@H](CF)C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1 -US06133279,6,CC(=O)Oc1c(C(C)(C)C)cc2c(c1C(C)(C)C)CC(C)(CNC(=N)NN)O2>>CC1(CNC(=N)NN)Cc2c(cc(C(C)(C)C)c(O)c2C(C)(C)C)O1 -US08623866B2,2,FC1(F)CCNC1.O=C(O)c1ccncc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1>>O=C(Nc1cnccc1C(=O)N1CCC(F)(F)C1)c1nc(C2CC2)ccc1Nc1cncnc1 -US20060281695A1,7,O=[N+]([O-])c1ccc(Cl)cc1Sc1ccc(Cl)cc1>>Nc1ccc(Cl)cc1Sc1ccc(Cl)cc1 -US20070213338A1,6,C[C@@H](c1cccc(COC2=NN3C(=NNC3C(F)(F)F)c3ccccc32)n1)N(CCc1cccc(Br)c1)C(=O)OC(C)(C)C>>C[C@H](NCCc1cccc(Br)c1)c1cccc(COC2=NN3C(=NNC3C(F)(F)F)c3ccccc32)n1 -US20080161294A1,7,C[C@H](CO)N=Cc1ccccc1NC(=O)c1ccc(N2CCCC2)cc1Cl>>C[C@H](CO)NCc1ccccc1NC(=O)c1ccc(N2CCCC2)cc1Cl -US07915448B2,3,CC(=O)Cl.Cc1ccccc1NS(C)(=O)=O>>CC(=O)c1ccc(NS(C)(=O)=O)c(C)c1 -US20140142085A1,3,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncccc1Br.O=C1Cc2c(Br)cccc2N1>>CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncccc1-c1cccc2c1CC(=O)N2 -US09056859B2,6,O=C(Cc1ccc(-n2cnnn2)cc1)N1C2CCC1CN(Cc1ccccc1)C2>>O=C(Cc1ccc(-n2cnnn2)cc1)N1C2CCC1CNC2 -US06020345,8,OCc1cccc(-c2ccco2)n1>>O=Cc1cccc(-c2ccco2)n1 -US20130231328A1,2,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(=O)O)CC4)CC1.Nc1ccc(F)cn1>>CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(=O)Nc2ccc(F)cn2)CC4)CC1 -US07319104B2,1,CCOC(=O)C(C)(C)Oc1ccc(CCNCc2ccc(C(F)(F)F)cc2)cc1.O=[N+]([O-])c1ccc(Cl)nc1>>CCOC(=O)C(C)(C)Oc1ccc(CCN(Cc2ccc(C(F)(F)F)cc2)c2ccc([N+](=O)[O-])cn2)cc1 -US20070021443A1,4,Nc1cnc(-n2cnc3ccccc32)nc1N[C@@H]1CCOc2c(F)cccc21.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cnc(-n3cnc4ccccc43)nc2n1[C@@H]1CCOc2c(F)cccc21 -US20100016366A1,1,CNCCCCCCCCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1.O=Cc1cc(Cl)c(Cl)cc1O>>CN(CCCCCCCCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)Cc1cc(Cl)c(Cl)cc1O -US20120101136A1,3,CC(C)Oc1ccc(-c2ncc(Br)s2)cc1C#N.CCOC(=O)CCCOc1ccc(B2OC(C)(C)C(C)(C)O2)c(CC)c1>>CCOC(=O)CCCOc1ccc(-c2cnc(-c3ccc(OC(C)C)c(C#N)c3)s2)c(CC)c1 -US07435744B2,2,Nc1ccc2[nH]c(=O)oc2c1.O=C(O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc2[nH]c(=O)oc2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1 -US20100292222A1,7,CN1CCN(CCOc2ccc(C3=CCN(c4ccc5nnc(C(F)(F)F)n5n4)CC3)cn2)CC1=O>>CN1CCN(CCOc2ccc(C3CCN(c4ccc5nnc(C(F)(F)F)n5n4)CC3)cn2)CC1=O -US20150148342A1,1,CC(C)(C)OC(=O)N1CCC(CCBr)CC1.Cn1c(=O)[nH]c2c(OCC3CCC3)c(Br)ccc21>>Cn1c(=O)n(CCC2CCN(C(=O)OC(C)(C)C)CC2)c2c(OCC3CCC3)c(Br)ccc21 -US20080275086A1,2,CC(C)(C)OC(=O)N1CC[C@H](N)C1.O=C(O)C1CC1>>CC(C)(C)OC(=O)N1CC[C@H](NC(=O)C2CC2)C1 -US20040014773A1,6,CC(=O)OCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c21>>O=c1[nH]c(NCc2ccc(Cl)c(Cl)c2)nc2ncn(CCCCO)c12 -US20050267150A1,2,CC(C(=O)O)c1ccccc1.CC1C(=O)N(C(=O)[C@H](C)N)c2cccc(N)c2-c2ccccc21>>CC(C(=O)N[C@@H](C)C(=O)N1C(=O)C(C)c2ccccc2-c2c(N)cccc21)c1ccccc1 -US20100311966A1,1,CC(C)OC1CN(C(=O)OC(C)(C)C)CCC1=O.NCc1ccccc1>>CC(C)O[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NCc1ccccc1 -US07557112B2,6,CN(C)CCOC1CCN(C(=O)OC(C)(C)C)CC1>>CN(C)CCOC1CCNCC1 -US04343945,2,Cc1ccccc1C(=O)Cl.Nc1nc(C(Cl)(Cl)Cl)ns1>>Cc1ccccc1C(=O)Nc1nc(C(Cl)(Cl)Cl)ns1 -US20070293532A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccnc(N)c1[N+](=O)[O-]>>Cc1ccnc(NC(=O)OC(C)(C)C)c1[N+](=O)[O-] -US20130281433A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc2c(=O)n(C)n(C)c2c1.CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(Cl)c3)sc2c1-c1ccc(Cl)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5c(=O)n(C)n(C)c5c4)c3)sc2c1-c1ccc(Cl)cc1 -US08324248B2,7,O=C(O)C1=C(c2ccc(Cl)cc2)CN(Cc2ccccc2)CC1>>O=C(O)C1CCN(Cc2ccccc2)CC1c1ccc(Cl)cc1 -US07151196B2,9,CCOC(=O)C1(CCF)Cc2c(ccc(OC)c2Cl)C1=O>>COc1ccc2c(c1Cl)CC(CCF)C2=O -US20070259862A1,9,CC(C)(C)OC(=O)N1CCC[C@@H]1C(N)=O>>CC(C)(C)OC(=O)N1CCC[C@@H]1C#N -US20120178732A1,2,C1CCNC1.O=C(O)c1ccc(Br)cc1F>>O=C(c1ccc(Br)cc1F)N1CCCC1 -US20150224071A1,1,CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(F)cc1F.OCCC1CCC1>>CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCCC2CCC2)cc1F -US20080004302A1,1,Clc1nccc(Nc2cc(COc3ccccc3)n[nH]2)n1.NCc1cc(C(N)=O)no1>>NC(=O)c1cc(CNc2nccc(Nc3cc(COc4ccccc4)n[nH]3)n2)on1 -US06620815B1,1,C1CNCCN1.COC(=O)c1ccccc1Br>>COC(=O)c1ccccc1N1CCNCC1 -US07842685B2,1,COC(=O)C1CNC1.O=Cc1ccc(-c2nc3ccc(C4(c5ccccc5)CC=CC4)nc3s2)c(F)c1>>COC(=O)C1CN(Cc2ccc(-c3nc4ccc(C5(c6ccccc6)CC=CC5)nc4s3)c(F)c2)C1 -US05468867,1,CC(C)C(N)C(C)C.O=Cc1ccc(Br)cc1>>CC(C)C(N=Cc1ccc(Br)cc1)C(C)C -US08957070B2,6,CCOC(=O)c1[nH]c2c(NS(=O)(=O)c3cccs3)cccc2c1C>>Cc1c(C(=O)O)[nH]c2c(NS(=O)(=O)c3cccs3)cccc12 -US20070172385A1,1,CC1(C)OCc2cc([C@@H](O)CN)ccc2O1.O=S1(=O)CCCc2ccc(CCCCOCCCCCCBr)cc21>>CC1(C)OCc2cc([C@@H](O)CNCCCCCCOCCCCc3ccc4c(c3)S(=O)(=O)CCC4)ccc2O1 -US20100286191A1,2,COc1c(C(C)(C)C)cc(-c2nc(C3CCNCC3)cs2)cc1C(C)(C)C.O=C(O)Cn1ccnc1>>COc1c(C(C)(C)C)cc(-c2nc(C3CCN(C(=O)Cn4ccnc4)CC3)cs2)cc1C(C)(C)C -US08299077B2,6,CC(C)(C)OC(=O)N1CC(Oc2ccc(Br)nc2)C1>>Brc1ccc(OC2CNC2)cn1 -US20080214419A1,8,CC1=C(CC[C@@H](C)CO)C(C)(C)CCC1>>CC1=C(CC[C@@H](C)C=O)C(C)(C)CCC1 -US20120269724A1,1,CC(C)(C)Oc1ccccc1C=O.NCc1ccccn1>>CC(C)(C)Oc1ccccc1CNCc1ccccn1 -US20070082912A1,6,COC(=O)c1cc(N)cc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2cccc(F)c2F)c1>>Cc1ccc(-c2cc(Cl)ccc2OCc2cccc(F)c2F)n1-c1cc(N)cc(C(=O)O)c1 -US06525066B2,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COc1c(Cl)ccnc1C(=O)C1CC1>>COC=C(c1nccc(Cl)c1OC)C1CC1 -US20100331297A1,9,CC(C)(C)n1nc(C(O)c2ccccc2)c2c(N)ncnc21>>CC(C)(C)n1nc(Cc2ccccc2)c2c(N)ncnc21 -US06015825,1,C[Sn](C)(C)Cl.Cn1cccn1>>Cn1nccc1[Sn](C)(C)C -US20050026836A1,1,CC(C)(C)OC(=O)CN(c1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.N=C(N)N>>CC(C)(C)OC(=O)CN(c1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1 -US20130196964A1,1,CN=S(=O)(c1ccc(-c2noc(-c3cc(C)[nH]n3)n2)cc1)C(F)(F)F.ClCc1ccnc(N2CCN(C3CC3)CC2)c1>>CN=S(=O)(c1ccc(-c2noc(-c3cc(C)n(Cc4ccnc(N5CCN(C6CC6)CC5)c4)n3)n2)cc1)C(F)(F)F -US20080255202A1,9,NO.O=Cc1ccc(C(F)(F)F)cc1C(F)(F)F>>ON=Cc1ccc(C(F)(F)F)cc1C(F)(F)F -US07816475B2,1,ClCCCBr.Oc1ccc(Cl)cc1>>ClCCCOc1ccc(Cl)cc1 -US20140171446A1,2,CCC(=O)c1ccc(N)nc1.Cc1c(F)cncc1C(=O)O>>CCC(=O)c1ccc(NC(=O)c2cncc(F)c2C)nc1 -US08362038B2,6,CCOC(=O)c1cc(F)c(C)n(C(C)C)c1=O>>Cc1c(F)cc(C(=O)O)c(=O)n1C(C)C -US20070149546A1,1,C[C@@H](CO)N(C)C.Cn1ccnc1Sc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl>>C[C@@H](COc1cccc2ncnc(Nc3ccc(Sc4nccn4C)c(Cl)c3)c12)N(C)C -US20060205811A1,2,CC(C)OCCO.O=C(Cl)C1CC1>>CC(C)OCCOC(=O)C1CC1 -US20090149468A1,6,CC(Nc1cc(-c2cc3nccn3c(N3CC4CC3CN4C(=O)OC(C)(C)C)n2)ccn1)c1ccccc1>>C[C@H](Nc1cc(-c2cc3nccn3c(N3C[C@@H]4C[C@H]3CN4)n2)ccn1)c1ccccc1 -US20050188480A1,7,Nc1cccc(Nc2ccc([N+](=O)[O-])cn2)n1>>Nc1ccc(Nc2cccc(N)n2)nc1 -US04510141,7,COC(=O)c1nc2n(n1)-c1cccnc1N(c1cccc(Cl)c1)C2>>OCc1nc2n(n1)-c1cccnc1N(c1cccc(Cl)c1)C2 -US20130317045A1,1,Cc1cc(N)n[nH]1.Fc1ccc(C(F)(F)c2nc(Cl)c3ccsc3n2)cc1>>Cc1cc(Nc2nc(C(F)(F)c3ccc(F)cc3)nc3sccc23)n[nH]1 -US20090264404A1,1,CC(=O)OCCCCBr.c1cc(N2CCNCC2)c2ccsc2c1>>CC(=O)OCCCCN1CCN(c2cccc3sccc23)CC1 -US20040176431A1,2,Cc1ccc(C(C)N)o1.Nc1nc(Nc2ccc(S(=O)(=O)F)cc2)sc1C(=O)c1c(F)cccc1F>>Cc1ccc(C(C)NS(=O)(=O)c2ccc(Nc3nc(N)c(C(=O)c4c(F)cccc4F)s3)cc2)o1 -US20150218150A1,2,CN1CCc2ccc(-c3ccc(-c4cncc(N)c4)s3)cc2C1=O.O=S(=O)(Cl)c1ccc(F)cc1F>>CN1CCc2ccc(-c3ccc(-c4cncc(NS(=O)(=O)c5ccc(F)cc5F)c4)s3)cc2C1=O -US20050032830A1,7,Cc1nc(Oc2ccccc2)c([N+](=O)[O-])c(NCCCCCl)c1C>>Cc1nc(Oc2ccccc2)c(N)c(NCCCCCl)c1C -US20100009959A1,1,C#CCBr.C=Cc1ccccc1-c1[nH]c2cc(C(=O)OC)ccc2c1C1CCCCC1>>C#CCn1c(-c2ccccc2C=C)c(C2CCCCC2)c2ccc(C(=O)OC)cc21 -US05854237,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1.c1cc2n(c1)Cc1sccc1NC2>>O=C(c1ccc([N+](=O)[O-])cc1)N1Cc2cccn2Cc2sccc21 -US07521461B2,6,CCCCCCCN(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2C(=O)OC)cc1>>CCCCCCCN(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2C(=O)O)cc1 -US06294503B1,7,O=C1COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)c([N+](=O)[O-])c2N1>>Nc1c2c(cc(F)c1N1C(=O)C3=C(CCCC3)C1=O)OCC(=O)N2 -US05919943,1,BrCc1ccccc1.CCc1cc2cc(OC)ccc2[nH]1>>CCc1cc2cc(OC)ccc2n1Cc1ccccc1 -US20100041555A1,3,C=CC[Sn](CCCC)(CCCC)CCCC.COc1cc(Cl)nnc1Oc1ccccc1C>>C=CCc1cc(OC)c(Oc2ccccc2C)nn1 -US20130302357A1,2,COC(=O)C1Cc2ccc([N+](=O)[O-])cc2N1.COc1cc(C(=O)Cl)c([N+](=O)[O-])cc1OCc1ccccc1>>COC(=O)C1Cc2ccc([N+](=O)[O-])cc2N1C(=O)c1cc(OC)c(OCc2ccccc2)cc1[N+](=O)[O-] -US20060211678A1,6,COCCn1ccc(OCc2ccccc2)cc1=O>>COCCn1ccc(O)cc1=O -US08362241B2,6,COc1cncc(Nc2ncccc2-c2nc(C)nc3c2ncn3C2CCCCO2)c1>>COc1cncc(Nc2ncccc2-c2nc(C)nc3[nH]cnc23)c1 -US04231944,7,CCOC(=O)/C(F)=C(C)\C=C\c1c(C)sc(C)c1C>>CC(/C=C/c1c(C)sc(C)c1C)=C(\F)CO -US06218431B1,6,CCCCCc1c(COC(C)=O)nc(C(C)C)c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1-c1ccc(F)cc1>>CCCCCc1c(CO)nc(C(C)C)c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1-c1ccc(F)cc1 -US20140051679A1,1,CC1(C)OB(c2ccc(O)c([N+](=O)[O-])c2)OC1(C)C.CN1CCC(O)CC1>>CN1CCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2[N+](=O)[O-])CC1 -US20010034351A1,7,CC(=O)c1cc(N)ccc1Oc1ccccc1>>CCc1cc(N)ccc1Oc1ccccc1 -US20140107097A1,1,CCOC(=O)C(C=O)c1ccccc1.Nc1ccc(Br)cc1>>CCOC(=O)C(C=Nc1ccc(Br)cc1)c1ccccc1 -US06180636B2,7,CCOC(=O)c1cc2c(Nc3cccc(Cl)c3)ncnc2[nH]1>>OCc1cc2c(Nc3cccc(Cl)c3)ncnc2[nH]1 -US20100056527A1,2,CC(C)C(=O)Cl.Cc1cc(N)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12>>Cc1cc(NC(=O)C(C)C)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 -US08481742B2,1,BrCc1ccc2c(Br)c(I)ccc2c1.CCOP(OCC)OCC>>CCOP(=O)(Cc1ccc2c(Br)c(I)ccc2c1)OCC -US20070287838A1,2,CCOC(=O)N(C)c1c(Oc2ccc(N)cc2)ccnc1N>>Cn1c(=O)[nH]c2nccc(Oc3ccc(N)cc3)c21 -US05998436,1,COc1ccc(CN)cc1.Nc1nc(F)c(Cl)cc1F>>COc1ccc(CNc2nc(N)c(F)cc2Cl)cc1 -US07618978B2,1,CC[C@H](C)N.COC(=O)c1cc(Cl)nc(C2OCCCO2)c1>>CC[C@H](C)Nc1cc(C(=O)OC)cc(C2OCCCO2)n1 -US20120095216A1,9,C[C@H](c1ccccc1)N1CCOC(c2ccc(C(=O)O)cc2)CC1.N>>C[C@H](c1ccccc1)N1CCOC(c2ccc(C(N)=O)cc2)CC1 -US20130231328A1,2,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(N)C#N)CC4)CC1.O=C(Cl)OCc1ccccc1>>CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(C#N)NC(=O)OCc2ccccc2)CC4)CC1 -US20110201643A1,6,CN(C)CCCC(=O)N1CCc2cc(C(=O)NOC3CCCCO3)ccc2C1>>CN(C)CCCC(=O)N1CCc2cc(C(=O)NO)ccc2C1 -US20100105655A1,7,COc1cc(N(C)CC(=O)OC(C)(C)C)ccc1[N+](=O)[O-]>>COc1cc(N(C)CC(=O)OC(C)(C)C)ccc1N -US06716857B2,3,C=C(Br)CN1CCCC1=O.CCCC[Sn](CCCC)(CCCC)c1cccnc1>>C=C(CN1CCCC1=O)c1cccnc1 -US04613607,1,C=C[C@H]1CNCC[C@H]1CC[C@@H](O)c1ccnc2ccc(OC)cc12.C=O>>C=C[C@H]1CN(C)CC[C@H]1CC[C@@H](O)c1ccnc2ccc(OC)cc12 -US07220773B2,3,CCOC(=O)CP(=O)(OCC)OCC.COCOc1cc(C=O)ccc1OC>>CCOC(=O)/C=C/c1ccc(OC)c(OCOC)c1 -US20020072514A1,1,CCS(=O)(=O)NC1CCCOc2c(C)cc(Cl)cc21.CI>>CCS(=O)(=O)N(C)C1CCCOc2c(C)cc(Cl)cc21 -US20130303515A1,1,CCN.O=Cc1ccc(Cl)cc1>>CCNCc1ccc(Cl)cc1 -US20150158815A1,3,COc1cc(B(O)O)c(F)cn1.NC(=O)C(Nc1cncc(Br)c1)c1ccccc1>>COc1cc(-c2cncc(NC(C(N)=O)c3ccccc3)c2)c(F)cn1 -US06114390,6,CC(C)(C)OC(=O)NCc1ccc2c(c1)CN(C(N)=O)C2>>NCc1ccc2c(c1)CN(C(N)=O)C2 -US20070142362A1,3,C=O.CCCCC(=O)Cc1ccsc1>>C=C(C(=O)CCCC)c1ccsc1 -US07179823B1,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1cn(Cc2ccc(OCc3csc(-c4ccccc4)n3)cc2)nc1-c1cccs1>>CCOC(=O)/C=C/c1cn(Cc2ccc(OCc3csc(-c4ccccc4)n3)cc2)nc1-c1cccs1 -US06143764,2,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C=Nc1ccc(Cl)cc1>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(Cl)cc4)cc3)c2cc1OC -US20130324531A1,2,COc1cc(C(=O)OCC(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F.NCCOCCO>>COc1cc(C(=O)OCC(=O)NCCOCCO)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F -US20050255575A1,3,C#Cc1ccc([N+](=O)[O-])cc1.CCOC(=O)/C=C\I>>CCOC(=O)C=CC#Cc1ccc([N+](=O)[O-])cc1 -US05344843,6,COC(=O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1F>>O=C(O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1F -US20140030189A1,1,CC(C)(C)OC(=O)NC(=N)NC(=O)OC(C)(C)C.CC(C)(C)[Si](C)(C)Oc1ccc(CO)cc1Br>>CC(C)(C)OC(=O)NC(=N)N(Cc1ccc(O[Si](C)(C)C(C)(C)C)c(Br)c1)C(=O)OC(C)(C)C -US20030092712A1,2,COc1ccc(CN2Cc3c(-c4ccccc4Cl)cc(N)cc3N(c3c(Cl)cccc3Cl)C2=O)cc1.Cn1cnc(S(=O)(=O)Cl)c1>>COc1ccc(CN2Cc3c(-c4ccccc4Cl)cc(NS(=O)(=O)c4cn(C)cn4)cc3N(c3c(Cl)cccc3Cl)C2=O)cc1 -US20040122057A1,6,CCOC(=O)C(OCC)c1c(F)cc(Oc2ccc(OC)cc2)cc1F>>CCOC(C(=O)O)c1c(F)cc(Oc2ccc(OC)cc2)cc1F -US20100298315A1,1,COc1ccc2nnc(Cl)n2n1.O=C(NCCN1CCCC1)Nc1nc2ccc(S)cc2s1>>COc1ccc2nnc(Sc3ccc4nc(NC(=O)NCCN5CCCC5)sc4c3)n2n1 -US20030018194A1,7,C=CC1(C2(C)OCCO2)CC1>>CCC1(C2(C)OCCO2)CC1 -US20120252815A1,3,CC1(C)CCC(C)(C)c2cc(B3OC(C)(C)C(C)(C)O3)ccc21.O=C1CCN(c2nc(Br)cs2)CC1>>CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCC(=O)CC4)n3)ccc21 -US07846960B2,1,CNc1c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc1F.COC(=O)c1ccc(C=O)cc1C>>COC(=O)c1ccc(CN(C)c2c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc2F)cc1C -US20100256698A1,6,COc1ccc2c(=O)n(CCNC(=O)OC(C)(C)C)c(C)c(-c3ccccc3)c2c1>>COc1ccc2c(=O)n(CCN)c(C)c(-c3ccccc3)c2c1 -US08211925B2,6,CCOC(=O)Cc1csc(NC(=O)c2cc(OCC)cc(OCC)c2)n1>>CCOc1cc(OCC)cc(C(=O)Nc2nc(CC(=O)O)cs2)c1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCCN1CCCCC1.Oc1ccc2cccnc2c1>>COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1OCCN1CCCCC1 -US20080207691A1,6,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@H](N2CCCCC2=O)CC1>>O=C1CCCCN1[C@@H]1CC[C@@H](O)CC1 -US08288419B2,7,CC1(c2nc(Cn3ccc([N+](=O)[O-])n3)cs2)OCCO1>>CC1(c2nc(Cn3ccc(N)n3)cs2)OCCO1 -US08962876B2,2,CC(C)(C)C(=O)Cl.CC(C)N>>CC(C)NC(=O)C(C)(C)C -US20060247263A1,1,CNc1cc(-c2ccccc2)c2ncn(Cc3ccccc3)c2c1.CSc1nccc(Cl)n1>>CSc1nccc(N(C)c2cc(-c3ccccc3)c3ncn(Cc4ccccc4)c3c2)n1 -US20150045340A1,6,COC(=O)C(O)COc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)NC(=N)c1ccc(OCC(O)C(=O)O)cc1 -US20150065447A1,3,C[C@H](NC(=O)c1cc(F)c(N2CC(CC#N)(n3cc(B4OC(C)(C)C(C)(C)O4)cn3)C2)cc1F)C(F)(F)F.Cc1n[nH]c(C)c1Br>>Cc1n[nH]c(C)c1-c1cnn(C2(CC#N)CN(c3cc(F)c(C(=O)N[C@@H](C)C(F)(F)F)cc3F)C2)c1 -US20150152047A1,1,CC(C)=O.CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1ccc(CN2CCNCC2)c(C(F)(F)F)c1>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1ccc(CN2CCN(C(C)C)CC2)c(C(F)(F)F)c1 -US20010003782A1,1,C[C@H](CCC(=O)O)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3.ClCc1ccccc1>>C[C@H](CCC(=O)OCc1ccccc1)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3 -US20110021479A1,2,CCC(=O)Cl.CCOc1ccc2c(c1-c1ncnc3c(C(=O)NC4CCNCC4)c[nH]c13)OCO2>>CCOc1ccc2c(c1-c1ncnc3c(C(=O)NC4CCN(C(=O)CC)CC4)c[nH]c13)OCO2 -US20140018533A1,3,CCOC(=O)C1=C(N2CCC(N3CCOCC3)CC2)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(N2CCC(N3CCOCC3)CC2)OC(=Cc2c[nH]c3ncccc23)C1=O -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.Cc1cc(B2OC(C)(C)C(C)(C)O2)n(C)n1>>CCCNC(=O)c1nnc2c(-c3cc(C)nn3C)cccc2c1N -US20150274663A1,1,CC[C@@H]1CC[C@H](O)CC1.Oc1ccc(Br)cc1>>CC[C@@H]1CC[C@@H](Oc2ccc(Br)cc2)CC1 -US08242124B2,7,COc1cnc(-n2cnc(C(C)=O)n2)c2[nH]ccc12>>COc1cnc(-n2cnc(C(C)O)n2)c2[nH]ccc12 -US20140329862A1,6,CCOC(=O)CCNC(=O)c1ccc(N[C@@H](CC(C)C)c2ccc(-c3ccc(C(F)(F)F)cn3)cc2)nc1>>CC(C)C[C@H](Nc1ccc(C(=O)NCCC(=O)O)cn1)c1ccc(-c2ccc(C(F)(F)F)cn2)cc1 -US07064124B2,2,COC1=C(OC)C(=O)C(Cc2ccc(OCc3cccnc3)c(C(=O)O)c2)=C(C)C1=O.COc1ccc(N)cc1>>COC1=C(OC)C(=O)C(Cc2ccc(OCc3cccnc3)c(C(=O)Nc3ccc(OC)cc3)c2)=C(C)C1=O -US08987248B2,2,CCc1ccc(C2CC(N)CN(C(=O)N3CCCC3)C2)cc1.O=C=Nc1ccc(F)cc1>>CCc1ccc(C2CC(NC(=O)Nc3ccc(F)cc3)CN(C(=O)N3CCCC3)C2)cc1 -US09034850B2,6,Cc1c(N2CCN(Cc3ccc(C(F)(F)F)o3)C(CO)C2)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F>>Cc1c(N2CCN(Cc3ccc(C(F)(F)F)o3)C(CO)C2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F -US07332510B2,1,Cc1nc(C#Cc2ccnc(Cl)c2)c[nH]1.FC(F)(F)c1nccc(Cl)n1>>Cc1nc(C#Cc2ccnc(Cl)c2)cn1-c1ccnc(C(F)(F)F)n1 -US07179934B2,2,CCC/C=C(\C)C(=O)O.O=C1N[C@@H](c2ccccc2)[C@@H](c2ccccc2)O1>>CCC/C=C(\C)C(=O)N1C(=O)O[C@H](c2ccccc2)[C@@H]1c1ccccc1 -US06498251B1,2,CN.COC(=O)Cn1c2c(c3ccccc31)CCN(C(=O)OC(C)(C)C)C2>>CNC(=O)Cn1c2c(c3ccccc31)CCN(C(=O)OC(C)(C)C)C2 -US20100261755A1,7,COC(=O)c1ccnc(-c2ccc(C(F)(F)F)cc2F)c1>>COC(=O)C1CCNC(c2ccc(C(F)(F)F)cc2F)C1 -US20150079035A1,1,CCOC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.NC1CCCCCCC1>>CCOC(=O)c1ccc(NC2CCCCCCC2)c([N+](=O)[O-])c1 -US05840917,6,CCOC(=O)c1ccc(Cl)o1>>O=C(O)c1ccc(Cl)o1 -US20070037817A1,2,COC(=O)Cl.Clc1cccc(C#C[C@H]2CC[C@H]3CNCCN32)c1>>COC(=O)N1CCN2[C@@H](CC[C@@H]2C#Cc2cccc(Cl)c2)C1 -US07659267B2,1,CC(C)(C)OC(=O)CBr.N#Cc1cccc(O)c1>>CC(C)(C)OC(=O)COc1cccc(C#N)c1 -US08129376B2,6,CC(C)(C)OC(=O)N1CCC(Nc2ccccc2C(F)(F)F)CC1>>FC(F)(F)c1ccccc1NC1CCNCC1 -US08110687B2,1,C1CCNC1.CC(C)(C)c1cc(CO)cc(C(=O)O)c1>>CC(C)(C)c1cc(CN2CCCC2)cc(C(=O)O)c1 -US20150191496A1,1,CC(C)(C)[Si](C)(C)O[C@H]1CCNC1=O.Cc1ccc(CBr)cc1>>Cc1ccc(CN2CC[C@H](O[Si](C)(C)C(C)(C)C)C2=O)cc1 -US20120245143A1,9,CC1c2cc(F)cc(I)c2C(=O)N1C1CCN(C(=O)OC(C)(C)C)CC1.N#C[Cu]>>CC1c2cc(F)cc(C#N)c2C(=O)N1C1CCN(C(=O)OC(C)(C)C)CC1 -US20130184284A1,6,CC(C)(C)OC(=O)N[C@@H]1CCCC[C@H]1N[C@H]1C[C@H]2C[C@@H]1N(c1ccc(C#N)cc1)C2>>N#Cc1ccc(N2C[C@@H]3C[C@H](N[C@@H]4CCCC[C@H]4N)[C@H]2C3)cc1 -US08748422B2,2,CC1CCCCN1CCN.O=C(O)c1ccc2c(=O)n(Cc3ccc(Cl)cc3)c(=O)[nH]c2c1>>CC1CCCCN1CCNC(=O)c1ccc2c(=O)n(Cc3ccc(Cl)cc3)c(=O)[nH]c2c1 -US07582761B2,1,C[C@@H]1CN(c2ncc(CO)cc2Cl)CCN1.O=C(Nc1cc(C(F)(F)F)cc2nc(Cl)[nH]c12)c1cc(F)c(F)c(F)c1>>C[C@@H]1CN(c2ncc(CO)cc2Cl)CCN1c1nc2cc(C(F)(F)F)cc(NC(=O)c3cc(F)c(F)c(F)c3)c2[nH]1 -US20100216813A1,1,C=O.N#Cc1ccc(N(Cc2ccccc2C(F)(F)F)[C@H]2CCNC2)cc1Cl>>CN1CC[C@H](N(Cc2ccccc2C(F)(F)F)c2ccc(C#N)c(Cl)c2)C1 -US04166131,9,CCC1(C)Cc2ccc(C(C)(O)C(=O)O)cc2C1>>CCC1(C)Cc2ccc(C(C)C(=O)O)cc2C1 -US08841455B2,1,CC(C)(C)OC(=O)NCCOS(C)(=O)=O.CCc1nn(Cc2cccc(O)n2)c2cccc(NC(=O)c3cnc4ccccn34)c12>>CCc1nn(Cc2cccc(OCCNC(=O)OC(C)(C)C)n2)c2cccc(NC(=O)c3cnc4ccccn34)c12 -US20110144146A1,7,CCCNC(=O)c1cc2cc(NS(=O)(=O)c3ccc(C(C)C)cc3)ccc2[nH]1>>CCCNCc1cc2cc(NS(=O)(=O)c3ccc(C(C)C)cc3)ccc2[nH]1 -US08921368B2,2,CC1(C)[C@H](O)CC[C@@H]1Nc1c(C(N)=O)cnn2cccc12.CS(=O)(=O)Cl>>CC1(C)[C@H](Nc2c(C(N)=O)cnn3cccc23)CC[C@@H]1OS(C)(=O)=O -US20070197577A1,6,CNC(=O)[C@H](Cc1csc2ccccc12)NC(=O)OC(C)(C)C>>CNC(=O)[C@@H](N)Cc1csc2ccccc12 -US20130190307A1,3,COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1N.Cc1nnc2cnc3ccc(Br)cc3n12>>COc1ncc(-c2ccc3ncc4nnc(C)n4c3c2)cc1N -US08288549B2,1,CCOC(=O)c1cc2cc(Cl)cc(C)c2nc1Cl.NC(Cc1c[nH]c2ccccc12)C(=O)O>>CCOC(=O)c1cc2cc(Cl)cc(C)c2nc1NC(Cc1c[nH]c2ccccc12)C(=O)O -US20030220392A1,1,Clc1cccc(Cl)c1CBr.O=Cc1cccc(O)c1>>O=Cc1cccc(OCc2c(Cl)cccc2Cl)c1 -US20100016282A1,1,CC(C)(C)OC(=O)N1CCNC(=O)CC1.ClCCN1CCCC1>>CC(C)(C)OC(=O)N1CCC(=O)N(CCN2CCCC2)CC1 -US20150239837A1,6,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1c1ncc(-c2cccc(Cl)c2)[nH]1>>F[C@H]1CN[C@H](c2ncc(-c3cccc(Cl)c3)[nH]2)C1 -US20150210688A1,1,CI.Cc1nc(C2(O)COC2)n(COCC[Si](C)(C)C)c1I>>COC1(c2nc(C)c(I)n2COCC[Si](C)(C)C)COC1 -US07504522B2,1,OC(c1ccc(Cl)cc1)c1ccc(Cl)cc1.OC1CN(C(c2ccccc2)c2ccccc2)C1>>Clc1ccc(C(OC2CN(C(c3ccccc3)c3ccccc3)C2)c2ccc(Cl)cc2)cc1 -US07507740B2,7,N#Cc1ccccc1COc1ccc([N+](=O)[O-])cc1Cl>>N#Cc1ccccc1COc1ccc(N)cc1Cl -US04609396,1,Cc1nc2ccccc2nc1Cl.Oc1ccc(OCc2ccccc2)cc1>>Cc1nc2ccccc2nc1Oc1ccc(OCc2ccccc2)cc1 -US06627651B1,6,COC(=O)C1=Cc2cc(OCC3CCCCC3)ccc2CCC1>>O=C(O)C1=Cc2cc(OCC3CCCCC3)ccc2CCC1 -US20130237525A1,7,CCOC(=O)c1cccc(-c2cncs2)c1>>OCc1cccc(-c2cncs2)c1 -US04203998,1,C1=COCCC1.Oc1cc(Cl)c(Cl)cc1Cl>>Clc1cc(Cl)c(OC2CCCCO2)cc1Cl -US20090149488A1,6,CCCOc1c(OC)cc(Cl)c2c1CN1CCc3cc(OC)c(OCc4ccccc4)cc3C1C2>>CCCOc1c(OC)cc(Cl)c2c1CN1CCc3cc(OC)c(O)cc3C1C2 -US20080312231A1,2,COC(=O)Cc1ccccc1N.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1>>COC(=O)Cc1ccccc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 -US04762829,2,CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC(=O)O.CCN1CCCC1CN>>CCN1CCCC1CNC(=O)C=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C -US20040133008A1,2,CC(C)(C)OC(=O)N(CCn1cccn1)c1ccc(N)cc1.Cc1ccc(C2=C(C(=O)O)CCCC2)cc1>>Cc1ccc(C2=C(C(=O)Nc3ccc(N(CCn4cccn4)C(=O)OC(C)(C)C)cc3)CCCC2)cc1 -US07947714B2,6,CC(C)CC1(C#N)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CC1(C#N)CC[NH2+]CC1 -US20130178625A1,1,COc1cccc(N)c1.O=[N+]([O-])c1c(OS(=O)(=O)C(F)(F)F)ccc2c1CCCC2>>COc1cccc(Nc2ccc3c(c2[N+](=O)[O-])CCCC3)c1 -US08063064B2,7,N#Cc1cc(Cl)cc(Oc2c(Br)ccc(C=O)c2F)c1>>N#Cc1cc(Cl)cc(Oc2c(Br)ccc(CO)c2F)c1 -US07820660B2,2,COC(=O)C(=O)Cl.Cn1c(C(C)(C)N)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O>>COC(=O)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C -US08263605B2,8,CC(C)(C)OC(=O)N1CC[C@H](CO)C1>>CC(C)(C)OC(=O)N1CC[C@H](C=O)C1 -US20040044057A1,7,O=C(CBr)c1cccnc1>>OC(CBr)c1cccnc1 -US08344135B2,2,CC(C)(C)OC(=O)Nc1cc(N)ccc1F.O=CO>>CC(C)(C)OC(=O)Nc1cc(NC=O)ccc1F -US20070225303A1,1,COC(=O)Cc1cccc(Cn2cnc3c(N)nc(Cl)nc32)c1.CSCCO>>COC(=O)Cc1cccc(Cn2cnc3c(N)nc(OCCSC)nc32)c1 -US20030092720A1,3,CN(C)C(=O)C1CCCN(c2nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c(=O)c2C=O)C1.COC(=O)CP(=O)(OCC(F)(F)F)OCC(F)(F)F>>COC(=O)/C=C/c1c(N2CCCC(C(=O)N(C)C)C2)nc2cc(C(=O)Nc3nc(C(C)(C)C)cs3)ccn2c1=O -US07074819B2,8,CC1(c2ccc(O)cc2)CSc2cc(O)ccc2C1CCCOc1ccc(OCCSCCCC(F)(F)C(F)(F)F)cc1.O=S([O-])OO>>CC1(c2ccc(O)cc2)CSc2cc(O)ccc2C1CCCOc1ccc(OCCS(=O)CCCC(F)(F)C(F)(F)F)cc1 -US20150119362A1,1,COC(=O)Cc1ccc(N)cn1.Clc1cccc(-c2cc(Cl)c3c(n2)CCC3)c1>>COC(=O)Cc1ccc(Nc2cc(-c3cccc(Cl)c3)nc3c2CCC3)cn1 -US07432288B2,1,CC(=O)c1cc2cc(N)ccc2o1.O=C1C(Cl)=C(c2ccccc2)C(=O)N1Cc1cccnc1>>CC(=O)c1cc2cc(NC3=C(c4ccccc4)C(=O)N(Cc4cccnc4)C3=O)ccc2o1 -US20110281854A1,1,C[C@@H]1CN[C@H](c2ccccc2)CO1.O=C1CSc2ccc(Br)cc2N1>>C[C@@H]1CN(c2ccc3c(c2)NC(=O)CS3)[C@H](c2ccccc2)CO1 -US08470816B2,2,CC(=O)N1CCC(C(=O)O)CC1.CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1CCNC[C@H]1c1ccc(Cl)cc1>>CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](c3ccc(Cl)cc3)C2)CC1 -US20090227555A2,2,CCOC(=O)c1cc(C#N)c(N2CC(C)(C(=O)O)C2)nc1C.NS(=O)(=O)c1ccc(Cl)s1>>CCOC(=O)c1cc(C#N)c(N2CC(C)(C(=O)NS(=O)(=O)c3ccc(Cl)s3)C2)nc1C -US08153544B2,5,CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.COCCl>>COCOc1ccc(C(C)(C)C)cc1C(C)(C)C -US06277790B1,7,CCC(=O)NC1CCOC1>>CCCNC1CCOC1 -US20090258882A1,3,COc1ccc(-c2ccc3ncnc(Cl)c3c2)cn1.OB(O)c1ccccc1>>COc1ccc(-c2ccc3ncnc(-c4ccccc4)c3c2)cn1 -US20020128481A1,9,Cc1nc2ccc(N)c(C)c2[nH]1.N#CN>>Cc1nc2ccc(NC(=N)N)c(C)c2[nH]1 -US08969568B2,3,CB1OB(C)OB(C)O1.COc1cc(C#N)cc(Br)c1OC>>COc1cc(C#N)cc(C)c1OC -US20140163009A1,1,FC(F)(F)c1ccc(Cl)nc1.Ic1cn[nH]c1>>FC(F)(F)c1ccc(-n2cc(I)cn2)nc1 -US07902201B2,2,Cc1onc(-c2ccccc2)c1COc1cnc(C(=O)O)cn1.NC1CCC(F)(F)CC1>>Cc1onc(-c2ccccc2)c1COc1cnc(C(=O)NC2CCC(F)(F)CC2)cn1 -US20090203689A1,1,N[C@@H]1CCC[C@H]1OCc1ccccc1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>OC[C@H]1OC(n2cnc3c(N[C@@H]4CCC[C@H]4OCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O -US20080318923A1,6,CN(C)C(=O)[C@H](Cc1ccccn1)NC(=O)OCC1c2ccccc2-c2ccccc21>>CN(C)C(=O)[C@@H](N)Cc1ccccn1 -US04447617,9,N.O=[N+]([O-])c1ccc2nc(Cl)sc2c1>>Nc1nc2ccc([N+](=O)[O-])cc2s1 -US08536160B2,7,CC(=O)O[C@H]1CC[C@@]2(C)C(=CC(=O)[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]32)C1>>CC(=O)O[C@H]1CC[C@@]2(C)C(CC(=O)[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]32)C1 -US06127361,7,CCOC(=O)[C@H]1C[C@@H](OCOC)CN1CCc1ccc(OC)cc1>>COCO[C@@H]1C[C@H](CO)N(CCc2ccc(OC)cc2)C1 -US04927822,1,CC(=O)SCCC(=O)Cl.CCOC(=O)C1NN=C(c2ccc3ccccc3c2)S1>>CCOC(=O)C1SC(c2ccc3ccccc3c2)=NN1C(=O)CCSC(C)=O -US07732461B2,1,NC1CCN(CC2Cn3c(=O)ccc4nccc2c43)CC1.O=Cc1cc2c(cn1)OCS2>>O=c1ccc2nccc3c2n1CC3CN1CCC(NCc2cc3c(cn2)OCS3)CC1 -US20070254881A1,2,COC1CCNCC1.COc1ccc(-n2nc(C(=O)O)cc2-c2c[nH]c(C)n2)cn1>>COc1ccc(-n2nc(C(=O)N3CCC(OC)CC3)cc2-c2c[nH]c(C)n2)cn1 -US20090005353A1,1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.NCCc1ccc(S(N)(=O)=O)cc1>>CC(C)(C)N1C(=O)C(NCCc2ccc(S(N)(=O)=O)cc2)=C(c2ccccc2)S1(=O)=O -US05843992,2,CC(C)CC(N)c1ccccc1.CCOC(=O)[C@@H]1O[C@H]1C(=O)[O-]>>CCOC(=O)[C@@H]1O[C@H]1C(=O)NC(CC(C)C)c1ccccc1 -US07220876B2,1,C=CCBr.COC(=O)c1c(C)cccc1CO[C@@H]1CCC[C@H](O)C1>>C=CCO[C@H]1CCC[C@@H](OCc2cccc(C)c2C(=O)OC)C1 -US20120101137A1,2,Cc1sc(C2CCCN2)cc1C(=O)Nc1ncc(F)s1.O=C(Cl)CCl>>Cc1sc(C2CCCN2C(=O)CCl)cc1C(=O)Nc1ncc(F)s1 -US06310081B1,2,O=C(O)c1ccc(S(=O)(=O)Cl)cc1O.Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1Br>>O=C(O)c1ccc(S(=O)(=O)Oc2c(Br)cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc2Br)cc1O -US20090137804A1,2,CCN(CC)c1ccc(Nc2cc(N)ncn2)cc1.O=C=Nc1c(F)cccc1F>>CCN(CC)c1ccc(Nc2cc(NC(=O)Nc3c(F)cccc3F)ncn2)cc1 -US20100298377A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc2[nH]nc(I)c2c1>>CC(C)(C)OC(=O)n1nc(I)c2cc([N+](=O)[O-])ccc21 -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=S)Nc4cccc(F)c4)cc3)cc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NC(=S)Nc4cccc(F)c4)cc3)cc2C1=O -US20150175594A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1c(N)sc2ccccc12>>CCOC(=O)c1c(NC(=O)OC(C)(C)C)sc2ccccc12 -US08691822B2,1,CC(C)(C)OC(=O)N1CCNCC1.ClC[C@H]1CO1>>CC(C)(C)OC(=O)N1CCN(C[C@@H]2CO2)CC1 -US20050038060A1,2,C=CC(=O)Cl.CN(C)C(=O)[C@@H]1Cc2ccccc2N1>>C=CC(=O)N1c2ccccc2C[C@H]1C(=O)N(C)C -US05783521,6,COc1cccc(-c2cccc(Oc3nc(OC)cc(OC)n3)c2C(=O)OCc2ccccc2)n1>>COc1cccc(-c2cccc(Oc3nc(OC)cc(OC)n3)c2C(=O)O)n1 -US04335127,1,CC(=O)c1ccccc1NC(=O)C(Cl)(Cl)Cl.NCCO>>CC(=NCCO)c1ccccc1NC(=O)C(Cl)(Cl)Cl -US20030083359A1,1,N[C@H]1CCCc2ccccc21.O=Cc1ccc(Cl)cc1Cl>>Clc1ccc(CN[C@H]2CCCc3ccccc32)c(Cl)c1 -US08318949B2,6,CCOC(=O)c1sc(N2CCN(CC(=O)NCc3ccc(F)cc3)C2=O)nc1C>>Cc1nc(N2CCN(CC(=O)NCc3ccc(F)cc3)C2=O)sc1C(=O)O -US07491819B1,7,N#Cc1ccccc1N1CCCCS1(=O)=O>>NCc1ccccc1N1CCCCS1(=O)=O -US08741897B2,1,C1COCCN1.CC(C)(CC(O)(Cc1cc2nc(C=O)ccc2[nH]1)C(F)(F)F)c1cc(Cl)cc2c1OCC2>>CC(C)(CC(O)(Cc1cc2nc(CN3CCOCC3)ccc2[nH]1)C(F)(F)F)c1cc(Cl)cc2c1OCC2 -US20100216788A1,6,COC(=O)c1cccc(Cn2ccc3cc([N+](=O)[O-])cc(Cl)c32)c1>>O=C(O)c1cccc(Cn2ccc3cc([N+](=O)[O-])cc(Cl)c32)c1 -US08748626B2,6,C[C@H](O)C(=O)N(C[C@@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1)C(C)(C)C>>C[C@H](O)C(=O)N(C[C@@H]1CNC[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1)C(C)(C)C -US20030225059A1,1,NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=CC1(c2ccccc2)CCC2(CC1)OCCO2>>FC(F)(F)c1cc(CNCC2(c3ccccc3)CCC3(CC2)OCCO3)cc(C(F)(F)F)c1 -US20140058098A1,2,CC(C)(N)CO.O=C(O)c1ccc2c(c1)-c1nc(-c3ncnn3-c3ccc(F)cc3F)cn1CCO2>>CC(C)(CO)NC(=O)c1ccc2c(c1)-c1nc(-c3ncnn3-c3ccc(F)cc3F)cn1CCO2 -US20110140043A1,7,O=C(c1cc(-c2ccccc2)cc(-c2ccccc2)c1)c1cc(-c2ccccc2)cc(-c2ccccc2)c1>>c1ccc(-c2cc(Cc3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc(-c3ccccc3)c2)cc1 -US08691809B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C1OCC(c2ccc(Br)cc2)O1>>CC1(C)OB(c2ccc(C3COC(=O)O3)cc2)OC1(C)C -US20140322355A1,2,CCc1cc(C2CC2)c(C(=O)OC)cc1C(=O)N1CCC(F)(c2ccc(C#N)cc2)CC1.NN>>CCc1cc(C2CC2)c(C(=O)NN)cc1C(=O)N1CCC(F)(c2ccc(C#N)cc2)CC1 -US08003670B2,1,CN(C)CCCl.O=S(=O)(c1cccc(O)c1)n1ccc2ccccc21>>CN(C)CCOc1cccc(S(=O)(=O)n2ccc3ccccc32)c1 -US20130040930A1,6,CCC1CN(Cc2ccc(OC)cc2)C(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cc1>>CCC1CNC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cc1 -US08049006B2,6,COC(=O)C(CNC(=O)OC(C)(C)C)Cc1cc(Cl)ccc1OC>>COc1ccc(Cl)cc1CC(CNC(=O)OC(C)(C)C)C(=O)O -US20120309766A1,6,CC(C)(C)OC(=O)Nc1ccc(CN2CC[C@@H](O)C2)cn1>>Nc1ccc(CN2CC[C@@H](O)C2)cn1 -US04861785,6,Fc1ccc(OC2CCC(OCc3ccccc3)CC2)cc1>>OC1CCC(Oc2ccc(F)cc2)CC1 -US20140088076A1,9,Cc1c(B2OC(C)(C)C(C)(C)O2)cnc(Cl)c1F>>Cc1c(F)cncc1B1OC(C)(C)C(C)(C)O1 -US07473693B2,2,NN1CCCCC1.O=C(O)c1cnc(-c2ccc(Br)cc2)c(-c2ccc(Br)cc2)n1>>O=C(NN1CCCCC1)c1cnc(-c2ccc(Br)cc2)c(-c2ccc(Br)cc2)n1 -US04052212,1,O=C(CBr)c1ccccc1.O=C(O)c1cc(O)c2ccccc2c1O>>O=C(COc1cc(C(=O)O)c(O)c2ccccc12)c1ccccc1 -US20090012129A1,3,CCCCCCCNC(=O)N(C)c1cccc(B2OC(C)(C)C(C)(C)O2)c1.CCCCOc1cc(/C=C(/OC)C(=O)OC)ccc1I>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(/OC)C(=O)OC)cc2OCCCC)c1 -US20100267780A1,1,NC(=O)c1cccc(-c2ccc(C=O)cn2)c1.NCCC1CC2CCC1C2>>NC(=O)c1cccc(-c2ccc(CNCCC3CC4CCC3C4)cn2)c1 -US20130289033A1,2,NCCc1c[nH]c2ccc(Cl)cc12.O=C(O)c1ccc(Cl)nn1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cl)nn1 -US20140011777A1,7,O=[N+]([O-])CC1(O)CCC2(CC1)OCCO2>>NCC1(O)CCC2(CC1)OCCO2 -US06677378B2,7,CNC(=O)c1cc(F)ccc1Oc1ccc(Cl)c(Cl)c1>>CNCc1cc(F)ccc1Oc1ccc(Cl)c(Cl)c1 -US20110082181A1,3,C=CC(C)C(O)c1c(C)noc1-c1ccc(Br)cc1.CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1>>C=CC(C)C(O)c1c(C)noc1-c1ccc(-c2ccc(C3(C(=O)OCC)CC3)cc2)cc1 -US20140336191A1,1,BrCc1ccccc1.COc1cc(C(C)=O)ccc1O>>COc1cc(C(C)=O)ccc1OCc1ccccc1 -US07709471B2,1,CCC1(CC)CN(C2CCCC2)c2nc(Cl)ncc2NC1=O.CI>>CCC1(CC)CN(C2CCCC2)c2nc(Cl)ncc2N(C)C1=O -US07482340B2,1,CNC.O=C(CCl)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1>>CN(C)CC(=O)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1 -US20130030012A1,1,CN1CCCn2c1cc(Cl)nc2=O.NCc1ccc(F)cc1>>CN1CCCn2c1cc(NCc1ccc(F)cc1)nc2=O -US20070082899A1,2,CNc1ccc2c(c1)nc(C(C)(C)OC)n2CC1CCOCC1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>COC(C)(C)c1nc2cc(N(C)S(=O)(=O)c3ccc([N+](=O)[O-])cc3)ccc2n1CC1CCOCC1 -US04970207,1,CN1CCNCC1.O=C(NC1N=C(c2ccccc2)c2ccccc2N(CCBr)C1=O)c1cc2ccccc2[nH]1>>CN1CCN(CCN2C(=O)C(NC(=O)c3cc4ccccc4[nH]3)N=C(c3ccccc3)c3ccccc32)CC1 -US07183290B2,2,N#C[C@@H]1CC(F)(F)CN1.O=C(Br)CBr>>N#C[C@@H]1CC(F)(F)CN1C(=O)CBr -US07943795B2,2,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc2cc(C(=O)Cl)ccc2c1.CNC>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc2cc(C(=O)N(C)C)ccc2c1 -US20100331326A1,1,Brc1ccc2c(c1)CCO2.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccc3c(c2)CCO3)C1=O -US20130267510A1,7,Cc1ccc(Oc2ncc([N+](=O)[O-])cn2)c2c1OCC21CC1>>Cc1ccc(Oc2ncc(N)cn2)c2c1OCC21CC1 -US20100298383A1,1,FC(F)(F)Cc1nc2cc(Cl)c(Cl)cc2[nH]1.O=[N+]([O-])c1cccc(CBr)c1>>O=[N+]([O-])c1cccc(Cn2c(CC(F)(F)F)nc3cc(Cl)c(Cl)cc32)c1 -US20150203475A1,2,C1COCCN1.Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(C(=O)O)c4c3)n2)c2ccccc12>>Nc1ccc(Oc2ccnc(Nc3ccc4[nH]nc(C(=O)N5CCOCC5)c4c3)n2)c2ccccc12 -US04385181,6,Cc1ccc(S(=O)(=O)OC=CC2=C(C(=O)OC(c3ccccc3)c3ccccc3)N3C(=O)C(NC(=O)OC(C)(C)C)C3S(=O)C2)cc1>>Cc1ccc(S(=O)(=O)OC=CC2=C(C(=O)OC(c3ccccc3)c3ccccc3)N3C(=O)C(N)C3S(=O)C2)cc1 -US08283366B2,3,COC(=O)c1ncc(C=O)c(C)c1OCc1ccccc1.Fc1ccc([Mg+])cc1>>COC(=O)c1ncc(C(O)c2ccc(F)cc2)c(C)c1OCc1ccccc1 -US20070082880A1,6,COC(=O)c1cc2c(Nc3ccc4[nH]ccc4c3C)c(C#N)cnc2s1>>Cc1c(Nc2c(C#N)cnc3sc(C(=O)O)cc23)ccc2[nH]ccc12 -US06313137B1,3,CN(C)C=O.Cc1cccc(C(C)C)c1Br>>Cc1cccc(C(C)C)c1C=O -US20100256124A1,2,Nc1cccc(F)c1Br.O=C(Cl)C=Cc1ccccc1>>O=C(C=Cc1ccccc1)Nc1cccc(F)c1Br -US20090275606A1,2,C=CCC1(S(=O)(=O)Cl)CC1.Cc1c(=O)n2c(c3[nH]c(=O)n(-c4ccc(I)cc4F)c13)CCC2>>C=CCC1(S(=O)(=O)n2c(=O)n(-c3ccc(I)cc3F)c3c(C)c(=O)n4c(c32)CCC4)CC1 -US20140080822A1,2,COC(=O)c1c(N)ccc2c1CCn1nccc1-2.O=S(=O)(Cl)c1ccc(F)cc1Br>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2Br)ccc2c1CCn1nccc1-2 -US20050187228A1,1,NCCNc1nc(Cl)nc2c1ncn2C1CCCC1.N[C@H]1CC[C@H](N)CC1>>NCCNc1nc(N[C@@H]2CC[C@@H](N)CC2)nc2c1ncn2C1CCCC1 -US20110118230A1,3,COc1cc(I)c(N)cn1.OB(O)c1cc(Br)cnc1F>>COc1cc(-c2cc(Br)cnc2F)c(N)cn1 -US04710585,1,CCC(C)CCCCCBr.Oc1ccc(O)cc1>>CCC(C)CCCCCOc1ccc(O)cc1 -US20070021405A1,6,CC(C)(C)OC(=O)N1CCC(n2cnc(-c3ccccc3)c2)CC1>>c1ccc(-c2cn(C3CCNCC3)cn2)cc1 -US20140155419A1,1,Cc1ccc(C(NC(=O)Cc2ccc(O)c(C)c2)c2ccccc2)c(C)c1.Cc1ncccc1CCl>>Cc1ccc(C(NC(=O)Cc2ccc(OCc3cccnc3C)c(C)c2)c2ccccc2)c(C)c1 -US20040082607A1,6,CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2cccs2)c2cc(C(=O)O)ccc2c1=O>>CC(C)Cn1c(CN)c(-c2cccs2)c2cc(C(=O)O)ccc2c1=O -US20120101134A1,6,CCCc1c(CCCC(=O)OCC)cccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1>>CCCc1c(CCCC(=O)O)cccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 -US20080312282A1,2,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.O=C=Nc1ccccc1>>CC1(C)OB(c2ccc(NC(=O)Nc3ccccc3)nc2)OC1(C)C -US20090023740A1,1,CNCc1ccc(OC)cc1OC.O=S(=O)(Nc1nccs1)c1ccc(Br)cc1F>>COc1ccc(CN(C)c2ccc(S(=O)(=O)Nc3nccs3)c(F)c2)c(OC)c1 -US20100048568A1,2,Cc1nc(-c2ccccn2)ncc1C(=O)O.Nn1ccc2c(F)cccc21>>Cc1nc(-c2ccccn2)ncc1C(=O)Nn1ccc2c(F)cccc21 -US20040024034A1,1,CCOC(=O)C(C)(Cc1ccccc1)Oc1ccc(O)cc1.Cc1oc(-c2ccccc2)nc1CCO>>CCOC(=O)C(C)(Cc1ccccc1)Oc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1 -US08173650B2,2,CC(C)(O)C(=O)O.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN(C(=O)C(C)(C)O)C3)n(C)c2n1 -US20140350019A1,6,CCOC(=O)COc1ccc(F)c(NCc2cccc(-c3cccc(F)c3)c2)c1F>>O=C(O)COc1ccc(F)c(NCc2cccc(-c3cccc(F)c3)c2)c1F -US20130165464A1,9,N.O=C(O)c1cn(-c2ccnc(Cl)c2)cc1-c1ccccc1Cl>>NC(=O)c1cn(-c2ccnc(Cl)c2)cc1-c1ccccc1Cl -US07326791B2,2,C[C@H](NC(=O)c1ccc(C(=O)O)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1.c1cn(C[C@H]2CCCN2)cn1>>C[C@H](NC(=O)c1ccc(C(=O)N2CCC[C@@H]2Cn2ccnc2)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1 -US20140066455A1,1,CC(=O)N1CCNCC1.COC(=O)c1ccc(Br)cc1>>COC(=O)c1ccc(N2CCN(C(C)=O)CC2)cc1 -US07659274B2,3,C=Cc1ccccc1.Nc1nccn2c(C3CCC3)nc(I)c12>>Nc1nccn2c(C3CCC3)nc(/C=C/c3ccccc3)c12 -US20060160811A1,1,CC1CCNCC1.Fc1cc(F)c(-c2c(Cl)nc3ncncc3c2Cl)c(F)c1>>CC1CCN(c2nc3ncncc3c(Cl)c2-c2c(F)cc(F)cc2F)CC1 -US09102637B2,6,NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)CCCN1C(=O)c2ccccc2C1=O>>NCCCC(=O)Nc1sc(Nc2ccc3ccccc3c2)nc1C(N)=O -US08344135B2,2,CC(C)(C#N)c1cccc(C(=O)Cl)c1.Nc1ccc(Cl)c(O)c1>>CC(C)(C#N)c1cccc(C(=O)Nc2ccc(Cl)c(O)c2)c1 -US20040192685A1,6,COc1ccc2c(c1)CCN(c1ccccc1)C2c1ccc(I)cc1>>Oc1ccc2c(c1)CCN(c1ccccc1)C2c1ccc(I)cc1 -US20090030003A1,6,C[C@@H]1CN(Cc2ccccc2)C[C@H]1c1nc2c(cnn2C2CCCC2)c(=O)[nH]1>>C[C@@H]1CNC[C@H]1c1nc2c(cnn2C2CCCC2)c(=O)[nH]1 -US08044070B2,1,CC(C)(C)OC(=O)N1CCC(O)C1.Clc1ncc(Br)cn1>>CC(C)(C)OC(=O)N1CCC(Oc2ncc(Br)cn2)C1 -US08957089B2,6,CC(C)(C)OC(=O)N1CCN(C(=O)COc2ccc3c(c2)C(C2(c4ccc(Cl)cc4)CCC2)=NCC3)CC1>>O=C(COc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)=NCC2)N1CCNCC1 -US06166037,7,O=C([C@@H]1CCC=C[C@H]1c1ccccc1)N1CC(CN2CCC(c3ccccc3)CC2)C(c2ccccc2)C1>>O=C([C@@H]1CCCC[C@H]1c1ccccc1)N1CC(CN2CCC(c3ccccc3)CC2)C(c2ccccc2)C1 -US20070249670A1,2,COC(=O)[C@@H](NC(=O)c1cc(Cl)c(Cl)cc1N)C1CCCCC1.Cc1cccc(C)c1N=C=O>>COC(=O)[C@@H](NC(=O)c1cc(Cl)c(Cl)cc1NC(=O)Nc1c(C)cccc1C)C1CCCCC1 -US20100227887A1,2,CCOC(=O)c1cc(Cl)cc(C)n1.Nc1ccc(Cl)cn1>>Cc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)n1 -US20150225371A1,1,CCc1c(N)ncnc1Cl.Cc1cc(-c2cn(CCN3CCC3)c(C3CCNCC3)n2)ccc1F>>CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C)c3)cn2CCN2CCC2)CC1 -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=O)c4ccc(C)cc4)cc3)ccc2C1=O>>Cc1ccc(C(=O)Nc2ccc(-c3ccc4c(c3)CN([C@H](C(=O)O)C(C)C)C4=O)cc2)cc1 -US04496590,6,COc1ccc(Nc2ccccc2C(=O)O)c(C)c1>>Cc1cc(O)ccc1Nc1ccccc1C(=O)O -US20070072847A1,6,CCOC(=O)CN1CCC(C2CCN(C(=O)[C@@H](Cc3cc(C)c(O)c(C)c3)OC(=O)N3CCC(n4nc(-c5ccccc5)[nH]c4=O)CC3)CC2)CC1>>Cc1cc(C[C@@H](OC(=O)N2CCC(n3nc(-c4ccccc4)[nH]c3=O)CC2)C(=O)N2CCC(C3CCN(CC(=O)O)CC3)CC2)cc(C)c1O -US04880806,1,CCc1c(F)c([N+](=O)[O-])cc(F)c1N1CCN(C)CC1.NC1CC1>>CCc1c(NC2CC2)c([N+](=O)[O-])cc(F)c1N1CCN(C)CC1 -US20080064720A1,1,Clc1ccc2cc(OCc3ccccc3)ccc2n1.Oc1ccccc1>>c1ccc(COc2ccc3nc(Oc4ccccc4)ccc3c2)cc1 -US20030199578A1,2,Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12.O=C(Cl)c1ccco1>>O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)c1ccco1 -US08604205B2,1,CC(C)(C)C(=O)n1ncc2cc(NC3CCCNC3)ccc21.CSc1ccc(C=O)cc1>>CSc1ccc(CN2CCCC(Nc3ccc4c(cnn4C(=O)C(C)(C)C)c3)C2)cc1 -US20140148416A1,3,Cc1cccc(C)c1B(O)O.O=[N+]([O-])c1ccc(Cl)nc1>>Cc1cccc(C)c1-c1ccc([N+](=O)[O-])cn1 -US06258824B1,1,CI.Cn1cncc1C(O)(c1ccc(Cl)nc1)c1ccc2[nH]c(=O)cc(-c3cccc(Cl)c3)c2c1>>Cn1cncc1C(O)(c1ccc(Cl)nc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C -US20120183660A1,1,BrC1CCCC1.CCOC(=O)c1cccc(O)c1>>CCOC(=O)c1cccc(OC2CCCC2)c1 -US20090312381A1,2,CC(C)(N)c1cccc(C(F)(F)F)c1.O=C(O)Cn1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O>>CC(C)(NC(=O)Cn1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O)c1cccc(C(F)(F)F)c1 -US07332483B2,1,CN1CCNCC1.O=C(Nc1cccc(NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])c1)c1ccnc(N2CCOCC2)c1>>CN1CCN(c2ccc([N+](=O)[O-])c(C(=O)Nc3cccc(NC(=O)c4ccnc(N5CCOCC5)c4)c3)c2)CC1 -US20060287291A1,1,C[C@H]1CN[C@H](C)CN1.O=[N+]([O-])c1cc(CBr)c2occc2c1>>C[C@H]1CN[C@H](C)CN1Cc1cc([N+](=O)[O-])cc2ccoc12 -US20110312974A1,2,CCNCc1cc(C(F)(F)F)ccc1-c1cccc(CC(=O)OCC)n1.O=C(Cl)C1CC1>>CCOC(=O)Cc1cccc(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)C2CC2)n1 -US06093732,3,C#CCO.COc1cc(I)cc2c(O)c(C(=O)NCc3ccc(Cl)cc3)cnc12>>COc1cc(C#CCO)cc2c(O)c(C(=O)NCc3ccc(Cl)cc3)cnc12 -US20090312310A1,6,COC(=O)[C@H]1CCN(C(=O)C2=C(C(C)C)N3C(=N[C@@](C)(c4ccc(Cl)cc4)[C@H]3c3ccc(Cl)cc3)S2)C1>>CC(C)C1=C(C(=O)N2CC[C@H](C(=O)O)C2)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21 -US04054570,1,CC(O)(C1=CCNCC1)c1ccc(F)cc1.O=C(CCCCl)c1ccc(F)cc1>>CC(O)(C1=CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(F)cc1 -US20090264650A1,1,BrCC1CC1.O=C1NCCC1c1ccccc1>>O=C1C(c2ccccc2)CCN1CC1CC1 -US04563464,1,CCCCBr.COC(=O)C1(Cl)CC2C=CC1NC2>>CCCCN1CC2C=CC1C(Cl)(C(=O)OC)C2 -US20010034343A1,6,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3n2CC(F)(F)F)CC1>>FC(F)(F)Cn1c(N2CCCNCC2)nc2ccccc21 -US20060160832A1,2,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C(Cl)Oc1ccccc1>>COc1cc2nccc(Oc3ccc(NC(=O)Oc4ccccc4)cc3)c2cc1OC -US04105653,9,N#CC(Cl)Cc1ccc(C(=O)O)cc1>>N#CCCc1ccc(C(=O)O)cc1 -US20050176775A1,2,CC(=O)OC(C)=O.Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1cnc(CN)cn1>>CC(=O)NCc1cnc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cn1 -US20110034507A1,6,COC(=O)c1ccc(Cn2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc32)cc1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2c(ccn2Cc2ccc(C(=O)O)cc2)c1 -US04310540,2,CC1(C)C(C=C(Cl)Cl)C1C(=O)O.OCc1ccccc1OC(F)F>>CC1(C)C(C=C(Cl)Cl)C1C(=O)OCc1ccccc1OC(F)F -US20090137609A1,3,CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)cc1C)CC.COC(=O)Cc1ccccc1Br>>CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(-c3ccccc3CC(=O)OC)cc2)cc1C)CC -US20070142305A1,1,BrCCCBr.COc1cc2c(cc1O)CCC2=O>>COc1cc2c(cc1OCCCBr)CCC2=O -US20040006104A1,6,CC(=O)Oc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1>>CC(=O)Oc1ccc(C[C@H](N)C(=O)OCc2ccccc2)cc1 -US20140011800A1,1,C[C@H]1CN(C(=O)C2(C#N)CC2)C[C@H]1Nc1c(C(N)=O)cnn2cc(Br)cc12.Cc1cn[nH]c1>>Cc1cnn(-c2cc3c(N[C@@H]4CN(C(=O)C5(C#N)CC5)C[C@@H]4C)c(C(N)=O)cnn3c2)c1 -US07423159B2,1,CI.O=C1NC(=O)C(=Cc2ccc([N+](=O)[O-])cc2)S1>>CN1C(=O)SC(=Cc2ccc([N+](=O)[O-])cc2)C1=O -US05646171,1,BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCCCc1nc(C(=O)C(C)(C)C)c(C#N)[nH]1>>CCCCc1nc(C(=O)C(C)(C)C)c(C#N)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20130295261A1,2,CCCCCC1CCC(C(=O)O)CC1.N[C@H]1CO[C@@H]2[C@@H](NC(=O)C3CC3)CO[C@H]12>>CCCCCC1CCC(C(=O)N[C@H]2CO[C@@H]3[C@@H](NC(=O)C4CC4)CO[C@H]23)CC1 -US20080045521A1,6,COC(=O)[C@H](Cc1ccc(NC(=O)Cc2ccc3c(n2)NCCC3)cc1)NC(=O)c1c(Cl)cccc1Cl>>O=C(Cc1ccc2c(n1)NCCC2)Nc1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)O)cc1 -US20060270706A1,7,O=C1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C/C1=C\c1ccn(Cc2cscn2)n1>>OC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C/C1=C\c1ccn(Cc2cscn2)n1 -US20130040930A1,2,Cc1cc(C(F)(F)F)cnc1N1CCNCC1.O=C(O)c1ccc(N2CCCS2(=O)=O)cc1N1CCCS1(=O)=O>>Cc1cc(C(F)(F)F)cnc1N1CCN(C(=O)c2ccc(N3CCCS3(=O)=O)cc2N2CCCS2(=O)=O)CC1 -US04678793,3,CC(=O)Cl.CC1(C)CCSc2ccccc21>>CC(=O)c1ccc2c(c1)C(C)(C)CCS2 -US20150274704A1,1,CNC1CCC2(CCCN(C(=O)OC(C)(C)C)C2)C1.Clc1ncc(Cl)c(Cl)n1>>CN(c1nc(Cl)ncc1Cl)C1CCC2(CCCN(C(=O)OC(C)(C)C)C2)C1 -US20070135501A1,1,CC(C)(C)OC(=O)N[C@@](C)(CO)CCc1ccc(O)cc1.CCCCCCCOS(C)(=O)=O>>CCCCCCCOc1ccc(CC[C@](C)(CO)NC(=O)OC(C)(C)C)cc1 -US20110257208A1,2,O=C=NC1CCCCC1.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>O=C(NC1CCCCC1)N1Cc2ncnc(Nc3cnc4ccccc4c3)c2C1 -US20110288299A1,1,CCBr.CCOC(=O)c1ccc(Nc2cc3c4c(c2)CCCC4(C)CCC3)cc1>>CCOC(=O)c1ccc(N(CC)c2cc3c4c(c2)CCCC4(C)CCC3)cc1 -US20110275622A1,1,CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c2[nH]c(=O)ccc12.COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5cccc(C#CCCCBr)c5)c4)cc23)c1>>COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5cccc(C#CCCCNC[C@H](O[Si](C)(C)C(C)(C)C)c6ccc(O)c7[nH]c(=O)ccc67)c5)c4)cc23)c1 -US20150099730A1,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C(C1CC1)N1CC[C@@H](CN2C(=O)C3(CC3)N=C2c2ccc(-c3ccc(OS(=O)(=O)C(F)(F)F)cc3)cc2)C1>>Cn1cc(-c2ccc(-c3ccc(C4=NC5(CC5)C(=O)N4C[C@@H]4CCN(C(=O)C5CC5)C4)cc3)cc2)cn1 -US20120095064A1,1,CC(=O)Nc1cc[nH]n1.Fc1cccc(F)c1CBr>>CC(=O)Nc1ccn(Cc2c(F)cccc2F)n1 -US08980629B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1cc2ncoc2cc1Br>>Cc1cc2ncoc2cc1-c1ccc(N)nc1 -US07482340B2,1,CS(=O)(=O)Nc1ccc(Oc2ccc3c(c2)CCC(c2cccc(O)c2)O3)nc1.O=[N+]([O-])c1ccc(Cl)nc1>>CS(=O)(=O)Nc1ccc(Oc2ccc3c(c2)CCC(c2cccc(Oc4ccc([N+](=O)[O-])cn4)c2)O3)nc1 -US20110189167A1,1,Clc1ccnc(Cl)c1.Nc1ccc(O)cc1F>>Nc1ccc(Oc2ccnc(Cl)c2)cc1F -US20130217715A1,6,COCN(c1cccc(-c2nn(C3CCN(C(=O)OC(C)(C)C)CC3)cc2-c2ccncc2)c1F)S(=O)(=O)c1cc(F)ccc1F>>COCN(c1cccc(-c2nn(C3CCNCC3)cc2-c2ccncc2)c1F)S(=O)(=O)c1cc(F)ccc1F -US20120289505A1,6,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=S)Nc4ccccc4C(F)(F)F)cc3)ccc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2cc(-c3ccc(NC(=S)Nc4ccccc4C(F)(F)F)cc3)ccc2C1=O -US20050143415A1,3,CCOC(=O)C(=O)CC(C)(C)c1ccccc1.[Mg+]c1ccccc1>>CCOC(=O)C(O)(CC(C)(C)c1ccccc1)c1ccccc1 -US04788010,2,COc1ccc(CC(CO)NCCC(c2ccccc2)c2ccccc2)cc1OC.O=C(Cl)OCc1ccccc1>>COc1ccc(CC(CO)N(CCC(c2ccccc2)c2ccccc2)C(=O)OCc2ccccc2)cc1OC -US20100063013A1,2,CC(C)(F)C[C@H](N[C@@](C#CCO)(c1ccc(Br)cc1)C(F)(F)F)C(=O)O.NC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(F)C[C@H](N[C@@](C#CCO)(c1ccc(Br)cc1)C(F)(F)F)C(=O)N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(N)=O -US08436210B2,2,CCCC(=O)O.NC1=CC(=O)CCC1>>CCCC(=O)NC1=CC(=O)CCC1 -US20130303559A1,7,Nc1nc(-n2nc(Sc3ccccc3F)c3ncccc32)nc(N)c1[N+](=O)[O-]>>Nc1nc(-n2nc(Sc3ccccc3F)c3ncccc32)nc(N)c1N -US20110059043A1,2,CCOc1cc(Cl)cc(Cl)c1C1=NC(N)C(=O)Nc2ccccc21.COCCOc1ccc(F)cc1C(=O)O>>CCOc1cc(Cl)cc(Cl)c1C1=NC(NC(=O)c2cc(F)ccc2OCCOC)C(=O)Nc2ccccc21 -US04417014,9,O=C(O)c1cc(Cl)c(Cl)cc1C(=O)O>>O=C(O)c1ccc(Cl)cc1C(=O)O -US20080275097A1,6,CN(CCNC(=O)OC(C)(C)C)C(=O)n1nc(Cn2nnc3c(Oc4cc(Cl)cc(C#N)c4)c(Cl)ccc32)c2cccnc21>>CN(CC[NH3+])C(=O)n1nc(Cn2nnc3c(Oc4cc(Cl)cc(C#N)c4)c(Cl)ccc32)c2cccnc21 -US20080249131A1,7,COc1cc(Cl)c2c(C)ccc([N+](=O)[O-])c2n1>>COc1cc(Cl)c2c(C)ccc(N)c2n1 -US07399759B2,6,CC(C)(C)OC(=O)CCOCCCc1cccc(-c2nc(=O)c3ccccc3s2)n1>>O=C(O)CCOCCCc1cccc(-c2nc(=O)c3ccccc3s2)n1 -US07449490B2,3,CCOC(=O)CC#N.COc1cccc(C(C)=O)c1>>CCOC(=O)C(C#N)=C(C)c1cccc(OC)c1 -US20100168418A1,1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCNCC1.O=CCn1c(=O)cnc2ccc(F)cc21>>CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cnc3ccc(F)cc32)CC1 -US20090221555A1,1,COc1ccc2c(c1N)CN(Cc1ccccc1)CC(=O)N2.CS(=O)(=O)N[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl>>COc1ccc2c(c1Nc1ncc(Cl)c(N[C@@H]3CCCC[C@H]3NS(C)(=O)=O)n1)CN(Cc1ccccc1)CC(=O)N2 -US20150191466A1,3,CC1(C)OB(c2cncnc2)OC1(C)C.COc1ccc(COc2ccc(Cn3cnc4cc(I)ccc43)cc2OC)cn1>>COc1ccc(COc2ccc(Cn3cnc4cc(-c5cncnc5)ccc43)cc2OC)cn1 -US20110098272A1,1,CC(OS(C)(=O)=O)c1ccon1.CNc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCNCC2)n1>>CNc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCN(C(C)c3ccon3)CC2)n1 -US06630600B1,3,CCOC(=O)C(OCC)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(=Cc1ccc(OCc2ccccc2)cc1)OCC -US05977118,2,CCc1[nH]n(C2CCCC2)c2nc(CO)nc(=O)c1-2.CS(=O)(=O)Cl>>CCc1[nH]n(C2CCCC2)c2nc(COS(C)(=O)=O)nc(=O)c1-2 -US07354939B2,2,COC(=O)c1cc(I)c[nH]1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cc(I)cn1S(=O)(=O)c1ccc(C)cc1 -US04734419,6,CCOC(=O)Cn1c(=O)n(Cc2ccc(Br)cc2F)c(=O)c2ccc(Cl)cc21>>O=C(O)Cn1c(=O)n(Cc2ccc(Br)cc2F)c(=O)c2ccc(Cl)cc21 -US09023846B2,6,CCOC(=O)c1c(Cl)c(C(C)(C)C)nn1C>>Cn1nc(C(C)(C)C)c(Cl)c1C(=O)O -US20130324530A1,1,CI.O[C@H](COCc1ccccc1)C(F)(F)F>>CO[C@H](COCc1ccccc1)C(F)(F)F -US08513248B2,2,FC(F)(F)c1cn2c(n1)CNCC2.O=C(Cl)c1ccc(F)cc1Cl>>O=C(c1ccc(F)cc1Cl)N1CCn2cc(C(F)(F)F)nc2C1 -US07919511B2,1,CCOC(=O)c1cnc(Cl)cc1Cl.NCCc1cccc(F)c1>>CCOC(=O)c1cnc(Cl)cc1NCCc1cccc(F)c1 -US20110319459A1,10,Br.C=CCCc1ccc(Br)cc1>>BrCCCCc1ccc(Br)cc1 -US20150023913A1,9,CCOC(=O)C1(C(=O)OC(C)(C)C)CC2CC(=O)CC2C1>>CCOC(=O)C1CC2CC(=O)CC2C1 -US08546374B2,3,N#Cc1cccnc1Cl.OB(O)c1c(F)cc(F)cc1F>>N#Cc1cccnc1-c1c(F)cc(F)cc1F -US20060209587A1,3,C=CCBr.CC1(C)COC(c2ccc(Br)cc2)OC1>>C=CCc1ccc(C2OCC(C)(C)CO2)cc1 -US20150148327A1,2,CNC.Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(CC(=O)O)nc2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(CC(=O)N(C)C)nc2)c1 -US04911861,1,CO.Oc1ccc(-c2ccccc2)cc1>>COc1ccc(-c2ccccc2)cc1 -US20120270795A1,9,CCOC(=O)COCCOCCOCCN=[N+]=[N-]>>CCOC(=O)COCCOCCOCCN -US20140275061A1,6,CC(C)(C)OC(=O)c1ccc(NC(=O)[C@@H]2c3ccccc3CCN2C(=O)C#Cc2cc(Cl)ccc2-n2cnnn2)cc1>>O=C(O)c1ccc(NC(=O)[C@@H]2c3ccccc3CCN2C(=O)C#Cc2cc(Cl)ccc2-n2cnnn2)cc1 -US20120264733A1,7,CCCCC#Cc1nc(C(C)(C)C)ncc1C(=O)N(CC(C)C)[C@H]1C[C@@H](C(=O)OC)CN(C(=O)OC(C)(C)C)C1>>CCCCCCc1nc(C(C)(C)C)ncc1C(=O)N(CC(C)C)[C@H]1C[C@@H](C(=O)OC)CN(C(=O)OC(C)(C)C)C1 -US20140200197A1,6,CC(C)(C)OC(=O)Nc1c(F)ccc(F)c1I>>Nc1c(F)ccc(F)c1I -US06013654,1,C1CNCCN1.N#Cc1cc(F)ccc1F>>N#Cc1cc(F)ccc1N1CCNCC1 -US20140088080A1,1,CC(C)(C)[S@@](N)=O.Cc1cccc(CCC(=O)OC(C)(C)C)c1C=O>>Cc1cccc(CCC(=O)OC(C)(C)C)c1/C=N/[S@@](=O)C(C)(C)C -US04997847,2,NCCCCCCCC(=O)O.O=S(=O)(Cl)c1cc(Cl)sc1Cl>>O=C(O)CCCCCCCNS(=O)(=O)c1cc(Cl)sc1Cl -US20110237607A1,9,Clc1nc(NC2Cc3ccccc3C2)c2nc[nH]c2n1.NN>>NNc1nc(NC2Cc3ccccc3C2)c2nc[nH]c2n1 -US20060004038A1,1,CC(C)(C)C(=O)OCCl.Cc1csc2c1c(O)c(C(=O)N(C)c1ccccc1)c(=O)n2C>>Cc1csc2c1c(OCOC(=O)C(C)(C)C)c(C(=O)N(C)c1ccccc1)c(=O)n2C -US05387692,1,C=CCO.COC(CBr)OC>>C=CCOCC(OC)OC -US04011335,3,C=C[Mg+].CCCCC(C)=CCCC(C)=O>>C=CC(C)(O)CCC=C(C)CCCC -US09115126B2,3,CN(CCOc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(F)(F)F)C(=O)OC(C)(C)C.CNc1cc(Cl)nc(C#N)c1N>>CNc1cc(-c2ccc(OCCN(C)C(=O)OC(C)(C)C)c(C(F)(F)F)c2)nc(C#N)c1N -US06593344B1,2,NCCCCN1CCC(c2c[nH]c3ccccc23)CC1.O=C(O)C=Cc1cccnc1>>O=C(C=Cc1cccnc1)NCCCCN1CCC(c2c[nH]c3ccccc23)CC1 -US20110071170A1,4,CC1(C)OCC(CC(=O)c2c(Cl)nc(N)nc2Cl)O1.COc1ccc(CNN)cc1>>COc1ccc(Cn2nc(CC3COC(C)(C)O3)c3c(Cl)nc(N)nc32)cc1 -US20090216014A1,1,BrCc1ccc(CBr)cc1.FC(F)(F)c1ccc2c(S)ccnc2c1>>FC(F)(F)c1ccc2c(SCc3ccc(CBr)cc3)ccnc2c1 -US07160891B2,1,Clc1ncnc2cc(OCCN3CCCC3)cc(OC3CCCC3)c12.Nc1c(Cl)ccc2ccoc12>>Clc1ccc2ccoc2c1Nc1ncnc2cc(OCCN3CCCC3)cc(OC3CCCC3)c12 -US20120264736A1,7,COC(=O)CC(C)C(c1c(F)ccc(F)c1F)S(=O)(=O)c1ccc(Cl)cc1>>CC(CCO)C(c1c(F)ccc(F)c1F)S(=O)(=O)c1ccc(Cl)cc1 -US05134111,3,CCI.COCOc1cccc2c(Br)cccc12>>CCc1cccc2c(OCOC)cccc12 -US20060035922A1,1,BrCc1ccccc1.N#Cc1ccc(O)cc1Cl>>N#Cc1ccc(OCc2ccccc2)cc1Cl -US20120050945A1,1,CN1CCCC1.COCCBr>>COCC[N+]1(C)CCCC1 -US08518972B2,7,CCOC(=O)c1cc(CN2CCOCC2)on1>>OCc1cc(CN2CCOCC2)on1 -US08822689B2,2,Cc1ccc2nn(CC(C)(N)C#N)nc2c1.FC(F)(F)c1ccc(C(=S)Cl)cc1>>Cc1ccc2nn(CC(C)(C#N)NC(=S)c3ccc(C(F)(F)F)cc3)nc2c1 -US20140288123A1,1,CC(O)c1ccc(Br)cc1.Clc1ncccn1>>CC(Oc1ncccn1)c1ccc(Br)cc1 -US20020087002A1,1,COc1c(F)cccc1CCl.OCCCCl>>COc1c(F)cccc1COCCCCl -US20150087658A1,1,CC[C@H](N)c1cc2cccc(F)c2c(=O)n1C1CC1.Cc1noc(-c2c(N)ncnc2Cl)n1>>CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(F)c2c(=O)n1C1CC1 -US07888352B2,3,CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1.Cc1nc(N)ncc1B1OC(C)(C)C(C)(C)O1>>Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2sc(CN3CCN(S(C)(=O)=O)CC3)cc2n1 -US20050250771A1,3,C#CC(OCC)(OCC)OCC.CS(=O)(=O)c1cncc(Br)c1>>CCOC(C#Cc1cncc(S(C)(=O)=O)c1)(OCC)OCC -US20070232627A1,1,CC(C)(C)OC(=O)Nc1ccc(O)cc1.O=C(Nc1ccc(F)c([N+](=O)[O-])c1)c1ccccc1>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccc(NC(=O)c3ccccc3)cc2[N+](=O)[O-])cc1 -US20130030012A1,1,Cc1ccc(O)cn1.N#Cc1cc(C=O)ccc1F>>Cc1ccc(Oc2ccc(C=O)cc2C#N)cn1 -US07977362B2,1,BrCc1ccc(-c2ncon2)cc1.O=S(=O)(N[C@@H]1CCCC[C@H]1CO)c1ccc(Cl)cc1>>O=S(=O)(c1ccc(Cl)cc1)N(Cc1ccc(-c2ncon2)cc1)[C@@H]1CCCC[C@H]1CO -US05455252,4,CCCCc1ccc(N)c(Br)c1.OCC(O)CO>>CCCCc1cc(Br)c2ncccc2c1 -US08088767B2,7,Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-]>>Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N -US07790898B2,2,COc1cccc(C2(O)CCCNC2)c1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>COc1cccc(C2(O)CCCN(C(=O)c3ccc([N+](=O)[O-])cc3)C2)c1 -US20080182881A1,8,CCCCCN(CCC12CC3CC(CC(C3)C1)C2)C(=O)NCCC(O)c1ccncc1>>CCCCCN(CCC12CC3CC(CC(C3)C1)C2)C(=O)NCCC(=O)c1ccncc1 -US04421758,1,O=C(OC[C@H]1CCC[C@H](OC(CBr)c2ccc(Cl)cc2Cl)O1)c1ccccc1.c1c[nH]cn1>>O=C(OC[C@H]1CCC[C@H](OC(Cn2ccnc2)c2ccc(Cl)cc2Cl)O1)c1ccccc1 -US05808083,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CC=C3C)cc1>>CC1=CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 -US05192781,1,CCOC(=O)CCCBr.NC(=S)[S-]>>CCOC(=O)CCCSC(N)=S -US20140323464A1,3,CC(C)(C)C=O.N#CCC(=O)N1CCCC(n2nc(-c3ccc(NC(=O)c4ccc(C(F)(F)F)cc4)cc3)c3c(N)ncnc32)C1>>CC(C)(C)C=C(C#N)C(=O)N1CCC[C@@H](n2nc(-c3ccc(NC(=O)c4ccc(C(F)(F)F)cc4)cc3)c3c(N)ncnc32)C1 -US20120295903A1,7,Cc1cc(NCCCCCO)c([N+](=O)[O-])cc1C>>Cc1cc(N)c(NCCCCCO)cc1C -US20090099157A1,2,O=C1CCCN1C1CCN(CC(O)Cn2nc(-c3ccc(C(F)(F)F)c(SCCN4CCCCC4)c3)c3c2CCNC3)CC1.O=S(=O)(Cl)c1ccccc1>>O=C1CCCN1C1CCN(CC(O)Cn2nc(-c3ccc(C(F)(F)F)c(SCCN4CCCCC4)c3)c3c2CCN(S(=O)(=O)c2ccccc2)C3)CC1 -US20140296506A1,3,CCCC[Sn](CCCC)(CCCC)c1ncccn1.Clc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(Br)s1>>Clc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(-c2ncccn2)s1 -US06753334B2,2,COC(=O)c1cnn(-c2cccc3ncccc23)c1C1CC1.N=C(N)N>>N=C(N)NC(=O)c1cnn(-c2cccc3ncccc23)c1C1CC1 -US20150191472A1,9,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC[C@@H]1[C@H]2OC(C)(C)O[C@H]2[C@H](c2c[nH]c3c(N=[N+]=[N-])ncnc23)N1C(=O)OC(C)(C)C>>CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC[C@@H]1[C@H]2OC(C)(C)O[C@H]2[C@H](c2c[nH]c3c(N)ncnc23)N1C(=O)OC(C)(C)C -US20110071150A1,3,Cc1cc(Cl)ncc1-c1ccc2c(c1)cc(-c1c(F)cccc1F)n2S(=O)(=O)c1ccccc1.OB(O)c1cncnc1>>Cc1cc(-c2cncnc2)ncc1-c1ccc2c(c1)cc(-c1c(F)cccc1F)n2S(=O)(=O)c1ccccc1 -US20110092554A1,1,COC(=O)C1(c2cc(O)cc(-c3ccc(C(F)(F)F)cc3)c2)CCC1.FC(F)(F)CI>>COC(=O)C1(c2cc(OCC(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)c2)CCC1 -US05019574,7,O=C1CCCCC1c1nc2ccccc2c([N+](=O)[O-])c1N1CCCCC1>>Nc1c(N2CCCCC2)c(C2CCCCC2=O)nc2ccccc12 -US08344135B2,1,Cc1ccc(NC(=O)OC(C)(C)C)cc1N.N#CSc1nc(Cl)ncc1[N+](=O)[O-]>>Cc1ccc(NC(=O)OC(C)(C)C)cc1Nc1ncc([N+](=O)[O-])c(SC#N)n1 -US05538976,1,Fc1cccc(CBr)c1.N#Cc1ccc(Nc2cncnc2)cc1>>N#Cc1ccc(N(Cc2cccc(F)c2)c2cncnc2)cc1 -US20100004284A1,2,Fc1ccc(Cc2noc([C@H]3CCCNC3)n2)cc1.O=C(Cl)c1ccc(F)cc1>>O=C(c1ccc(F)cc1)N1CCC[C@H](c2nc(Cc3ccc(F)cc3)no2)C1 -US20040006141A1,1,CCOC(=O)C(Cc1ccc(OCCOS(C)(=O)=O)cc1)Oc1ccc(C(C)C)cc1.[N-]=[N+]=[N-]>>CCOC(=O)C(Cc1ccc(OCCN=[N+]=[N-])cc1)Oc1ccc(C(C)C)cc1 -US05464865,7,CCCCCCCC(=O)Nc1ccc(CC(OC)OC)cc1>>CCCCCCCCNc1ccc(CC(OC)OC)cc1 -US05166218,1,CCOC(=O)CCCBr.Oc1ccc(CCNCC(O)COc2ccccc2)cc1>>CCOC(=O)CCCOc1ccc(CCNCC(O)COc2ccccc2)cc1 -US08022062B2,10,Cc1ccc(S(=O)CC(C)(C(F)(F)F)C(F)(F)F)cc1.O=C1CCC(=O)N1Br>>CC(CS(=O)c1ccc(CBr)cc1)(C(F)(F)F)C(F)(F)F -US20100087506A1,6,CCC[C@]1(O)CCN(C(=O)OCc2ccccc2)[C@H]1C>>CCC[C@]1(O)CCN[C@H]1C -US08546387B2,2,COc1ccc(-n2nc(C(C)(C)C)cc2N=C=O)cn1.Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)cc1F>>COc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)cn1 -US20080194596A1,6,Cc1ccc(Oc2ccc(Nc3ncnc4ccc(/C=C/CNC(=O)OC(C)(C)C)cc34)cc2Cl)cn1>>Cc1ccc(Oc2ccc(Nc3ncnc4ccc(/C=C/CN)cc34)cc2Cl)cn1 -US20100210592A1,3,CON(C)C(=O)C(NC(=O)OC(C)(C)C)c1ccc(C(F)(F)F)cc1.Ic1ccc(I)cc1>>CC(C)(C)OC(=O)NC(C(=O)c1ccc(I)cc1)c1ccc(C(F)(F)F)cc1 -US04044123,9,CCCCCC(O)C(NC(C)=O)C(=O)O>>CCCCCC(O)C(C=O)NC(C)=O -US20140315889A1,1,CCOC(=O)CCCCCBr.Cc1cc2c([nH]1)CC(C)(C)CC2=O>>CCOC(=O)CCCCCn1c(C)cc2c1CC(C)(C)CC2=O -US09139589B2,1,ClCCBr.FC1(F)CCNCC1>>FC1(F)CCN(CCCl)CC1 -US09155914B2,2,CCN.CN(C)CC(=O)O>>CCNC(=O)CN(C)C -US05948791,2,CS(=O)(=O)Cl.O[C@@H]1CC[C@@H](Nc2ccnc3cc(Cl)ccc23)CC1>>CS(=O)(=O)O[C@@H]1CC[C@@H](Nc2ccnc3cc(Cl)ccc23)CC1 -US04041048,2,C=CCNCC=C.CC1c2ccccc2CCON1C(=O)Cl>>C=CCN(CC=C)C(=O)N1OCCc2ccccc2C1C -US07741341B2,6,CC(C)N1CCC(NC(=O)c2nc3c(OCCO[Si](C)(C)C(C)(C)C)cccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1>>CC(C)N1CCC(NC(=O)c2nc3c(OCCO)cccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1 -US20080261996A1,1,Brc1cscn1.C[C@@H]1CNCCN1>>C[C@@H]1CN(c2cscn2)CCN1 -US20040063686A1,1,COc1cc([N+](=O)[O-])ccc1Cl.OCCN1CCCC1>>COc1cc([N+](=O)[O-])ccc1OCCN1CCCC1 -US20110118236A1,4,NN.O=C1CCCCC1C(=O)CC(F)(F)F>>FC(F)(F)Cc1n[nH]c2c1CCCC2 -US20140187786A1,1,O=[N+]([O-])c1ccc(F)cc1F.OCC(F)(F)F>>O=[N+]([O-])c1ccc(F)cc1OCC(F)(F)F -US08436008B2,2,CC1Cc2ccc(C3CCNCC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1.O=C(Cl)CC1CCCC1>>CC1Cc2ccc(C3CCN(C(=O)CC4CCCC4)CC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1 -US08822471B2,2,CCc1cnc(N2CCC(NC3CC3)CC2)cn1.O=C(O)c1ccc(-c2cnco2)c(F)c1>>CCc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)c(F)c3)C3CC3)CC2)cn1 -US20150266867A1,2,CC(C)(C)OC(=O)N=C(N1CC(CNC(=O)OC(C)(C)C)C1)N(Cc1cnn(C[C@H]2NC(=O)[C@H]2N)n1)C(=O)OC(C)(C)C.CC(C)(C)OC(=O)Nc1nc(/C(=N/OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)C(=O)O)cs1>>CC(C)(C)OC(=O)N=C(N1CC(CNC(=O)OC(C)(C)C)C1)N(Cc1cnn(C[C@H]2NC(=O)[C@H]2NC(=O)/C(=N\OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)c2csc(NC(=O)OC(C)(C)C)n2)n1)C(=O)OC(C)(C)C -US20100190826A1,7,CCOC(=O)c1cccc(Nc2ccc(C#N)cc2[N+](=O)[O-])c1>>CCOC(=O)c1cccc(Nc2ccc(C#N)cc2N)c1 -US06831081B2,7,O=C1COC[C@H]([C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)c2ccccc2)N1>>O=C1COC[C@H]([C@@H](O)c2ccccc2)N1 -US08609622B2,8,CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCC(F)F)cc3)c2)O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCC(F)F)cc3)c2)O[C@H](C=O)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1 -US09079880B2,6,COC(=O)c1cccc(OCC(=O)Nc2ccc(C#N)cc2)c1>>N#Cc1ccc(NC(=O)COc2cccc(C(=O)O)c2)cc1 -US20070037846A1,1,CCCCCBr.Cc1cc(C=O)ccc1O>>CCCCCOc1ccc(C=O)cc1C -US06271403B1,1,BrCc1ccccc1.C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCO)[C@H]3[C@@H]1C=CC2=O>>C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4C[C@@H](CCCCCO)[C@H]3[C@@H]1C=CC2=O -US20110009454A1,7,Cc1ccc(Sc2ccc(C#N)cc2)cc1Cl>>Cc1ccc(Sc2ccc(CN)cc2)cc1Cl -US20020002200A1,3,COc1cc(C=O)cc(OC)c1.O=C(O)Cc1ccc(O)cc1>>COc1cc(/C=C(/C(=O)O)c2ccc(O)cc2)cc(OC)c1 -US05620987,6,CC(C)(C)NC(=O)[C@@H]1CSCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1>>CC(C)(C)NC(=O)[C@@H]1CSCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O -US20090253680A1,2,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc(C)c1O.c1cc(C2CCNCC2)ccn1>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(c3ccncc3)CC2)cc(C)c1O -US20070149570A1,7,COc1cc(F)c(Br)cc1C(=O)O>>COc1cc(F)c(Br)cc1CO -US20150105366A1,4,Nc1ccc(I)cc1C(=O)O.O=C(CCc1ccccc1)C(F)(F)F>>Oc1c(Cc2ccccc2)c(C(F)(F)F)nc2ccc(I)cc12 -US20120214811A1,1,CN.Clc1cc(Cl)ncn1>>CNc1cc(Cl)ncn1 -US07858718B1,1,Brc1cccc2ccc(-c3cccc4ccccc34)nc12.CC(C)c1cccc(C(C)C)c1N>>CC(C)c1cccc(C(C)C)c1Nc1cccc2ccc(-c3cccc4ccccc34)nc12 -US20040034078A1,1,C1COCCN1.COC(=O)c1cccc2[nH]c(CSCCCl)nc12>>COC(=O)c1cccc2[nH]c(CSCCN3CCOCC3)nc12 -US20140162361A1,7,CCOC(=O)/C(=C\c1cccc(C(F)(F)F)c1)C(=O)C1CCC(c2ccccc2)CC1>>CCOC(=O)C(Cc1cccc(C(F)(F)F)c1)C(=O)C1CCC(c2ccccc2)CC1 -US20120083501A1,3,CN1C(=O)[C@]2(N=C1N)c1cc(Br)ccc1O[C@H]1CCCO[C@@H]12.OB(O)c1cccnc1F>>CN1C(=O)[C@]2(N=C1N)c1cc(-c3cccnc3F)ccc1O[C@H]1CCCO[C@@H]12 -US20110281854A1,7,C[C@H]1OC[C@@H](c2ccccc2)NC1=O>>C[C@@H]1CN[C@H](c2ccccc2)CO1 -US07714008B2,6,CC(=O)OCc1sc(Br)cc1C>>Cc1cc(Br)sc1CO -US05395846,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.NC1C2CC3CC1CC(O)(C3)C2>>OC12CC3CC(C1)C(NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(C3)C2 -US20090291942A1,7,CCc1nc2c(C)cc(C)nc2n1Cc1ccc(CC(=O)OC)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(CCO)cc1 -US20150225422A1,1,N#CCCl.NCc1ccccc1>>N#CCNCc1ccccc1 -US20080096935A1,1,BrCCCCBr.COC(=O)CCc1ccc(O)cc1>>COC(=O)CCc1ccc(OCCCCBr)cc1 -US20130109678A1,1,C1CSCCN1.Nc1cc(Cl)ccc1[N+](=O)[O-]>>Nc1cc(N2CCSCC2)ccc1[N+](=O)[O-] -US20050070592A1,6,COc1ccc(-c2cccc3c2c(C)c(-c2ccccc2)n3Cc2ccccc2)cc1>>Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cccc(-c3ccc(O)cc3)c12 -US20140296225A1,1,N#Cc1ccc2c(c1)CCC(=O)C2.N#Cc1ccc2c(c1)CCC(N1CCNCC1=O)C2>>N#Cc1ccc2c(c1)CCC(N1CCN(C3CCc4cc(C#N)ccc4C3)C(=O)C1)C2 -US08933105B2,2,Cc1ccc(S(=O)(=O)Cl)cn1.O=Cc1c[nH]c(-c2cccnc2Cl)c1>>Cc1ccc(S(=O)(=O)n2cc(C=O)cc2-c2cccnc2Cl)cn1 -US20120309796A1,2,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2N.O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1>>CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1cc(Cl)cc(Cl)c1 -US20060084807A1,2,CCOC(=O)[C@@H]1CCCN(CCNC(=O)c2ccc(F)cc2)C1.COc1cc2c(cc1OC)CNCC2>>COc1cc2c(cc1OC)CN(C(=O)[C@@H]1CCCN(CCNC(=O)c3ccc(F)cc3)C1)CC2 -US20050143452A1,9,CC1(CN=[N+]=[N-])Cc2cc(Cl)cc(-c3ccccc3)c2O1>>CC1(CN)Cc2cc(Cl)cc(-c3ccccc3)c2O1 -US20100249123A1,3,COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(Br)c2)cc1OC.OB(O)c1cncnc1>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(-c3cncnc3)c2)cc1OC -US20050113397A1,6,COCOC1CCC(c2c(-c3ccccc3)c(C)c(C#N)c3nc4ccccc4n23)C1>>Cc1c(-c2ccccc2)c(C2CCC(O)C2)n2c(nc3ccccc32)c1C#N -US08232312B2,9,N.O=C(O)c1c[nH]c2cc([N+](=O)[O-])ccc12>>NC(=O)c1c[nH]c2cc([N+](=O)[O-])ccc12 -US05538976,1,Fc1ccc(CBr)cc1.O=[N+]([O-])c1ccc(Nc2cncnc2)cc1>>O=[N+]([O-])c1ccc(N(Cc2ccc(F)cc2)c2cncnc2)cc1 -US09065150B2,1,C=COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO.CI>>C=COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC -US04703054,6,CC(NC(=O)OCc1ccccc1)C(=O)N1CC(=O)NC1(C)C>>CC(N)C(=O)N1CC(=O)NC1(C)C -US03983238,2,Cc1ncc(CO)cc1O.O=C(Cl)c1cccs1>>Cc1ncc(CO)cc1OC(=O)c1cccs1 -US04146645,2,CC(N)Cc1cccc([N+](=O)[O-])c1.COC(=O)Cl>>COC(=O)NC(C)Cc1cccc([N+](=O)[O-])c1 -US05616610,6,CCCN(C1CCC1)[C@H]1COc2c(F)ccc(OC)c2C1>>CCCN(C1CCC1)[C@H]1COc2c(F)ccc(O)c2C1 -US04062844,1,COc1cc2nc(Br)nc(N)c2cc1OC.N#CN1CCNCC1>>COc1cc2nc(N3CCN(C#N)CC3)nc(N)c2cc1OC -US07135470B2,3,CCOC(=O)c1csc(Br)c1.OB(O)c1ccc(F)cc1>>CCOC(=O)c1csc(-c2ccc(F)cc2)c1 -US20140275084A1,3,Cn1cnc(-c2cc(C#N)ccn2)c1Br.OB(O)c1ccc(Cl)c(OCc2ccccc2)c1>>Cn1cnc(-c2cc(C#N)ccn2)c1-c1ccc(Cl)c(OCc2ccccc2)c1 -US20100125061A1,2,COC(=O)Cc1cc2ccc(F)cc2c(C(=O)O)c1C.Fc1ccc(N2CCNCC2)cc1>>COC(=O)Cc1cc2ccc(F)cc2c(C(=O)N2CCN(c3ccc(F)cc3)CC2)c1C -US08546404B2,6,CC(C)(C)OC(=O)N1CCC(C#Cc2ncccn2)CC1>>C(#CC1CCNCC1)c1ncccn1 -US20130225584A1,2,CNC.O=C(O)c1cc(OCc2ccccc2)c(C(=O)OCc2ccccc2)cc1Br>>CN(C)C(=O)c1cc(OCc2ccccc2)c(C(=O)OCc2ccccc2)cc1Br -US20080193413A1,6,COC(=O)C(C)(C)c1ccccc1>>CC(C)(C(=O)O)c1ccccc1 -US20150175562A1,3,Brc1ccc(Br)c2ccccc12.CN(C)C=O>>O=Cc1ccc(Br)c2ccccc12 -US20090069327A1,8,CSc1cc(-c2cncnc2Nc2cc(NC(=O)OC(C)(C)C)ccc2C)ncn1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(NC(=O)OC(C)(C)C)cc1Nc1ncncc1-c1cc(S(C)=O)ncn1 -US20030144326A1,2,COc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(N2CCC3(CC2)OCCO3)cc1>>COc1ccc(S(=O)(=O)Nc2ccc(N3CCC4(CC3)OCCO4)cc2)cc1 -US05389649,8,Clc1ccc(C2COCCS2)cc1Cl.O=C(OO)c1cccc(Cl)c1>>O=S1CCOCC1c1ccc(Cl)c(Cl)c1 -US20050107374A1,1,CC1CNCCN1.O=[N+]([O-])c1ccc(F)c(F)c1>>CC1CN(c2ccc([N+](=O)[O-])cc2F)CCN1 -US06509361B1,1,CNCc1ccccc1.Cc1cccc(-n2nc(C)cc2-c2ccnc(Cl)c2)c1>>Cc1cccc(-n2nc(C)cc2-c2ccnc(N(C)Cc3ccccc3)c2)c1 -US04487781,1,C#CCO.CCOC(=O)CBr>>C#CCOCC(=O)OCC -US20150018542A1,1,C#Cc1ccc(C=O)cc1.CC(C)N>>C#Cc1ccc(CNC(C)C)cc1 -US08546376B2,4,C#Cc1cccc2c(=O)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)oc12.C[Si](C)(C)N=[N+]=[N-]>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(-c5c[nH]nn5)cccc4c3=O)cc2)CCC1 -US20140113882A1,7,N#Cc1ccc(F)c([N+](=O)[O-])c1>>N#Cc1ccc(F)c(N)c1 -US20040116471A1,1,COC(=O)c1cccc(CBr)c1.c1ccc2c(C3CCNCC3)c[nH]c2c1>>COC(=O)c1cccc(CN2CCC(c3c[nH]c4ccccc34)CC2)c1 -US08518972B2,1,Cc1nc[nH]c1C.O=C1CCC(N2Cc3c(OCc4ccc(CBr)cc4)cccc3C2=O)C(=O)N1>>Cc1ncn(Cc2ccc(COc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)cc2)c1C -US20110183964A1,7,COC(=O)/C=C/c1ccc(C2CCCN2CCc2c(C(C)(C)C)[nH]c3cc([N+](=O)[O-])ccc23)cc1>>COC(=O)/C=C/c1ccc(C2CCCN2CCc2c(C(C)(C)C)[nH]c3cc(N)ccc23)cc1 -US04889941,1,ClCC1CO1.O=c1cc(-c2ccccc2)oc2cc(O)ccc12>>O=c1cc(-c2ccccc2)oc2cc(OCC3CO3)ccc12 -US20100168103A1,2,CC(C)(C)N1CCN(CC2CCNCC2)CC1.O=C(O)CC(c1ccccc1)c1ccccc1>>CC(C)(C)N1CCN(CC2CCN(C(=O)CC(c3ccccc3)c3ccccc3)CC2)CC1 -US20060247320A1,9,CC(C)(C)C1CCc2nc3sc(C(=O)N[C@H](CN=[N+]=[N-])c4cccc(Br)c4)cc3cc2C1>>CC(C)(C)C1CCc2nc3sc(C(=O)N[C@H](CN)c4cccc(Br)c4)cc3cc2C1 -US20090281075A1,4,CC(C)(C)OC(=O)N1CC[C@@H](CNc2ncc(N)c(NCc3cc(Br)ccc3Cl)n2)C1.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2ncc3[nH]c(=O)n(Cc4cc(Br)ccc4Cl)c3n2)C1 -US20110288067A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCc2ccc(O)cc21>>CC(C)(C)OC(=O)N[C@@H]1CCc2ccc(O)cc21 -US04677112,6,COc1ccc(C(=O)N2C(=O)Cc3cccc(CC(=O)OCc4ccccc4)c32)cc1>>COc1ccc(C(=O)N2C(=O)Cc3cccc(CC(=O)O)c32)cc1 -US20090076004A1,1,CCOC(=O)Cc1c(C(=O)OCC)c2cc(O)ccc2n1-c1ccc(OC(F)(F)F)cc1.OB(O)c1ccc(Cl)c(Cl)c1>>CCOC(=O)Cc1c(C(=O)OCC)c2cc(Oc3ccc(Cl)c(Cl)c3)ccc2n1-c1ccc(OC(F)(F)F)cc1 -US20150018342A1,2,CCOC(=O)c1cc(C(=O)O)n2c1COCC2.C[C@H]1CCCN1>>CCOC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2 -US20030187268A1,7,COC(=O)c1cn(-c2ccc3ccccc3c2)cn1>>OCc1cn(-c2ccc3ccccc3c2)cn1 -US20060229346A1,2,CC(=O)Nc1nc(CCc2ccc(NC(=O)OC(C)(C)C)cc2)c(C(=O)O)s1.Nc1ccccc1>>CC(=O)Nc1nc(CCc2ccc(NC(=O)OC(C)(C)C)cc2)c(C(=O)Nc2ccccc2)s1 -US07754718B2,6,COC(=O)c1cc2ccc3c(c2c(-c2ccc4c(c2)OCO4)c1C(=O)OC)OCO3>>COC(=O)c1c(C(=O)O)cc2ccc3c(c2c1-c1ccc2c(c1)OCO2)OCO3 -US08134001B2,1,CS(=O)(=O)OC1CCOCC1.O=Cc1cc(Cl)ccc1O>>O=Cc1cc(Cl)ccc1OC1CCOCC1 -US04277497,6,COc1cccc(C(=O)c2ccccc2)c1>>O=C(c1ccccc1)c1cccc(O)c1 -US20080167307A1,1,CCCCCCCNCCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1.O=[N+]([O-])c1ccc(F)cc1>>CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ccc([N+](=O)[O-])cc1 -US20130131018A1,1,BrCC1CCC1.COc1cc(C=O)cc(OC)c1O>>COc1cc(C=O)cc(OC)c1OCC1CCC1 -US05635510,6,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccncc2)CC1>>N#CC1(c2ccncc2)CCNCC1 -US06316455B1,9,COC(=O)c1cccc2oc(-c3ccccc3)nc12.N>>NC(=O)c1cccc2oc(-c3ccccc3)nc12 -US20110269244A1,7,COC(=O)c1ccc2nccc(N3CCN(C(=O)OC(C)(C)C)CC3)c2c1>>CC(C)(C)OC(=O)N1CCN(c2ccnc3ccc(CO)cc23)CC1 -US20140128390A1,2,CCS(=O)(=O)Cl.Nc1ccc(-c2ncnc3cc(-c4ccc(F)cc4)sc23)cc1>>CCS(=O)(=O)Nc1ccc(-c2ncnc3cc(-c4ccc(F)cc4)sc23)cc1 -US04847256,6,CCOC(=O)c1cnn2c1NCC=C2c1cccc(C(F)(F)F)c1>>O=C(O)c1cnn2c1NCC=C2c1cccc(C(F)(F)F)c1 -US20110112065A1,1,BrCc1ccccc1.CCNCC1OCc2ccc(S(C)(=O)=O)cc2O1>>CCN(Cc1ccccc1)CC1OCc2ccc(S(C)(=O)=O)cc2O1 -US20150152093A1,1,Fc1cc(Cl)ccc1I.O=Cc1c[nH]cn1>>O=Cc1cn(-c2ccc(Cl)cc2F)cn1 -US20040176365A1,7,O=c1c(CCCc2ccncc2)cc2cccnc2n1-c1cccc([N+](=O)[O-])c1>>Nc1cccc(-n2c(=O)c(CCCc3ccncc3)cc3cccnc32)c1 -US07446118B2,6,CCOC(=O)CC(c1ccccc1)c1ccc2[nH]ccc2c1>>O=C(O)CC(c1ccccc1)c1ccc2[nH]ccc2c1 -US06514968B1,1,CCN(CC)CCCl.Cc1cccc2c3c(O)cccc3n(Cc3ccccc3)c12>>CCN(CC)CCOc1cccc2c1c1cccc(C)c1n2Cc1ccccc1 -US20090286778A1,1,CC(C)(C)OC(=O)Nc1cccc(N)c1.O=[N+]([O-])c1cccc(OCCBr)c1>>CC(C)(C)OC(=O)Nc1cccc(NCCOc2cccc([N+](=O)[O-])c2)c1 -US20100256364A1,2,C[C@H]1CN(Cc2ccc(N)cc2)CCN1C(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc(Cl)nc1>>C[C@H]1CN(Cc2ccc(NS(=O)(=O)c3ccc(Cl)nc3)cc2)CCN1C(=O)OC(C)(C)C -US09156840B2,2,CCCCCCC(=O)Cl.O=c1n(CO)c2ccccc2n1CCCCl>>CCCCCCC(=O)OCn1c(=O)n(CCCCl)c2ccccc21 -US08883782B2,1,COc1ccc2c(c1)[C@@]1(COC(N)=N1)c1cc(Br)cc(F)c1O2.O=C1CCCN1>>COc1ccc2c(c1)[C@@]1(COC(N)=N1)c1cc(N3CCCC3=O)cc(F)c1O2 -US20120245144A1,1,CCOC(=O)C(C)(C)Br.Cc1nc(-c2cn3c(n2)-c2ccc(-c4ccnn4C4CCCNC4)cc2OCC3)n(C(C)C)n1>>CCOC(=O)C(C)(C)N1CCCC(n2nccc2-c2ccc3c(c2)OCCn2cc(-c4nc(C)nn4C(C)C)nc2-3)C1 -US20100075946A1,3,CCc1ccccc1B(O)O.CCc1sc(C(=O)CCc2cc(C)c(O)c(C)c2)cc1Br>>CCc1ccccc1-c1cc(C(=O)CCc2cc(C)c(O)c(C)c2)sc1CC -US07687052B2,7,O=[N+]([O-])c1ccc(/C=C/c2ccc(OCCOCCOCCF)nc2)cc1>>Nc1ccc(/C=C/c2ccc(OCCOCCOCCF)nc2)cc1 -US20100272680A1,2,O=C(O)c1nc2c(C(F)(F)F)cc(C3CCC3)cn2c1Cl.O=C1OCCN1C1CCNCC1>>O=C(c1nc2c(C(F)(F)F)cc(C3CCC3)cn2c1Cl)N1CCC(N2CCOC2=O)CC1 -US07629462B2,1,CSc1nc(Cl)c(C#N)c(Cl)n1.Nc1c(F)cccc1F>>CSc1nc(Cl)c(C#N)c(Nc2c(F)cccc2F)n1 -US20100144717A1,6,CO[C@@H]1CN(CCn2c(=O)ccc3ccc(C#N)cc32)CC[C@H]1NC(=O)OC(C)(C)C>>CO[C@@H]1CN(CCn2c(=O)ccc3ccc(C#N)cc32)CC[C@H]1N -US08329726B2,1,ClCCCBr.Ic1c[nH]cn1>>ClCCCn1cnc(I)c1 -US20140065103A1,1,CC(N)Cn1cccn1.COC(=O)c1sc(C#CC(C)(C)C)cc1Br>>COC(=O)c1sc(C#CC(C)(C)C)cc1NC(C)Cn1cccn1 -US20080255153A1,2,NCC(N)=O.O=C(O)c1cnn2cc(Cc3ccc(F)c(C(F)(F)F)c3)cnc12>>NC(=O)CNC(=O)c1cnn2cc(Cc3ccc(F)c(C(F)(F)F)c3)cnc12 -US20130137675A1,6,CC(C)(C)OC(=O)N1CCCC(n2ccc(=O)c(-c3ccnn3-c3ccccc3)n2)C1>>O=c1ccn(C2CCCNC2)nc1-c1ccnn1-c1ccccc1 -US05856274,6,COC(=O)c1ccc(Cl)c(SC)c1OC>>COc1c(C(=O)O)ccc(Cl)c1SC -US20100197665A1,1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(Nc1n[nH]c2ccc(S(=O)(=O)c3cccc(F)c3)cc12)C(F)(F)F>>O=C(Nc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(S(=O)(=O)c3cccc(F)c3)cc12)C(F)(F)F -US20090192138A1,1,CC#CCn1c(Cl)c(C(=O)OC)c2nc[nH]c(=O)c21.COc1cccc(C(=O)CBr)c1>>CC#CCn1c(Cl)c(C(=O)OC)c2ncn(CC(=O)c3cccc(OC)c3)c(=O)c21 -US05591743,2,CC(=O)OC(C)=O.O=c1[nH]nc(Br)c(=O)[nH]1>>CC(=O)n1nc(Br)c(=O)[nH]c1=O -US20100197914A1,1,CCc1nnn([C@@H]2C=C[C@H](n3cnc4c(Cl)nc(Cl)nc43)C2)n1.CO[C@H]1CCC[C@@H]1N>>CCc1nnn([C@@H]2C=C[C@H](n3cnc4c(N[C@H]5CCC[C@@H]5OC)nc(Cl)nc43)C2)n1 -US20070219196A1,9,CCCc1nc2cnc3ccccc3c2n1CCC(=O)OCC.[NH4+]>>CCCc1nc2cnc3ccccc3c2n1CCC(N)=O -US07524860B2,2,CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)OC)n2n1.CN>>CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)NC)n2n1 -US20090004185A1,1,Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(Cl)nc2c1.c1ccc(N2CCNCC2)nc1>>Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N3CCN(c4ccccn4)CC3)nc2c1 -US20110212940A1,6,COc1ccc(Cc2cccnc2)cc1I>>Oc1ccc(Cc2cccnc2)cc1I -US20140275030A1,2,CC(=O)Cl.NCC1(c2ccccn2)COc2cccc([N+](=O)[O-])c2N1>>CC(=O)NCC1(c2ccccn2)COc2cccc([N+](=O)[O-])c2N1 -US20030004351A1,1,Nc1ccc(NS(N)(=O)=O)cc1.O=C1Nc2ccccc2C1=CO>>NS(=O)(=O)Nc1ccc(NC=C2C(=O)Nc3ccccc32)cc1 -US20050038104A1,1,CC(C)(C)OC(=O)NC1CCN(c2cc(F)c(C#N)c(F)c2)CC1.OCCN1CCOCC1>>CC(C)(C)OC(=O)NC1CCN(c2cc(F)c(C#N)c(OCCN3CCOCC3)c2)CC1 -US20120129811A1,2,CNS(=O)(=O)c1ccc(OC)c(N=C=S)c1.Cn1cnc2c(N)cccc21>>CNS(=O)(=O)c1ccc(OC)c(NC(=S)Nc2cccc3c2ncn3C)c1 -US20120101100A1,3,CCNC(=O)Nc1cc(-c2nc(-c3cccc(OC)n3)cs2)c(B(O)O)cn1.Cc1nnc(-c2cncc(Br)c2)o1>>CCNC(=O)Nc1cc(-c2nc(-c3cccc(OC)n3)cs2)c(-c2cncc(-c3nnc(C)o3)c2)cn1 -US20150080364A1,1,CC(C)(C)OC(=O)N1CCNCC1.COC(=O)c1cc(Cl)ccc1C=O>>COC(=O)c1cc(Cl)ccc1CN1CCN(C(=O)OC(C)(C)C)CC1 -US20030153568A1,7,CCNC(=O)Nc1nc2ccc(C#Cc3ccccc3)cc2s1>>CCNC(=O)Nc1nc2ccc(CCc3ccccc3)cc2s1 -US20100311966A1,6,CC[C@H]1[C@H](NC(=O)OC(C)(C)C)CN1C(c1ccccc1)c1ccccc1>>CC[C@@H]1NC[C@H]1NC(=O)OC(C)(C)C -US20070072906A1,1,Fc1ccc(CBr)c(F)c1.O=C(O)c1cccc(-n2c(-c3cc(Cl)ccc3O)ccc2C(F)(F)F)c1>>O=C(O)c1cccc(-n2c(-c3cc(Cl)ccc3OCc3ccc(F)cc3F)ccc2C(F)(F)F)c1 -US20120108583A1,7,O=[N+]([O-])c1cc(C(F)F)ccc1F>>Nc1cc(C(F)F)ccc1F -US06583154B1,1,C1CCNCC1.Cc1cc(Cl)c2oc(-c3ccccc3)cc2n1>>Cc1cc(N2CCCCC2)c2oc(-c3ccccc3)cc2n1 -US20110244481A1,3,C=C(B(O)O)c1ccccc1.CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(Br)n2)cc1>>C=C(c1ccccc1)c1nc(-c2ccc(O[Si](C)(C)C(C)(C)C)cc2)cnc1N -US20060189548A1,3,C#Cc1ccc(Cc2cc([C@@]3(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1.Cn1cc(I)cn1>>Cn1cc(C#Cc2ccc(Cc3cc([C@@]4(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)ccc3Cl)cc2)cn1 -US20020035266A1,7,Cc1nnnn1-c1ccc(Br)cc1[N+](=O)[O-]>>Cc1nnnn1-c1ccc(Br)cc1N -US04435322,9,CCOC(=O)CCN1C(=O)CC1(C(=O)OCC)C(=O)OCC>>CCOC(=O)CCN1C(=O)CC1C(=O)OCC -US20140213599A1,1,N#Cc1cc(CO)ccc1Oc1cccc(C(F)(F)F)c1.O=c1nc(Cl)cc2n1CCN2C1CC1>>N#Cc1cc(COc2cc3n(c(=O)n2)CCN3C2CC2)ccc1Oc1cccc(C(F)(F)F)c1 -US20060084644A1,3,CS(=O)(=O)c1cccc(B(O)O)c1.FC(F)(F)Oc1ccc(Nc2cc(N3CCCCC3)cc(Cl)n2)cc1>>CS(=O)(=O)c1cccc(-c2cc(N3CCCCC3)cc(Nc3ccc(OC(F)(F)F)cc3)n2)c1 -US06414149B1,7,CCCC(=O)O[C@H](C)c1nccc(N2CCC3(CC2)CC(=O)c2cc(Cl)ccc2O3)n1>>C[C@@H](O)c1nccc(N2CCC3(CC2)CC(=O)c2cc(Cl)ccc2O3)n1 -US08236950B2,1,CC(=O)Nc1ccc(Sc2ccc(O)cc2N)cc1.N#CCBr>>CC(=O)Nc1ccc(Sc2ccc(OCC#N)cc2N)cc1 -US20150252030A1,2,COC(=O)COc1c(C)cc(C)cc1Br.NN>>Cc1cc(C)c(OCC(=O)NN)c(Br)c1 -US20150018546A1,6,Cc1ncnc2c1c(NCc1ccccc1CNC(=O)OC(C)(C)C)cc(=O)n2O>>Cc1ncnc2c1c(NCc1ccccc1CN)cc(=O)n2O -US20020082254A1,2,COC(=O)c1ccc(OC(=O)Cl)cc1.NN1CCc2ccccc2C1>>COC(=O)c1ccc(OC(=O)NN2CCc3ccccc3C2)cc1 -US20020045777A1,2,CC(C)COC(=O)Cl.CN[C@@H]1CC[C@@H](OCCCCBr)CC1>>CC(C)COC(=O)N(C)[C@@H]1CC[C@@H](OCCCCBr)CC1 -US20100069425A1,1,OCc1ncccc1Br.Oc1cc(Cl)ccc1I>>Clc1ccc(I)c(OCc2ncccc2Br)c1 -US20150038528A1,6,COC(=O)C[C@@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1cccnc1>>N#Cc1nc(C(=O)N[C@H](CC(=O)O)c2cccnc2)c(O)c2ccc(Oc3ccccc3)cc12 -US09133224B2,1,CCOP(OCC)OCC.COc1c([N+](=O)[O-])ccc(CBr)c1Cl>>CCOP(=O)(Cc1ccc([N+](=O)[O-])c(OC)c1Cl)OCC -US05760050,6,COc1ccc2c3c(c(=O)oc2c1)CN(Cc1ccccc1)CC3>>COc1ccc2c3c(c(=O)oc2c1)CNCC3 -US20100286126A1,1,CC(=O)OCC(=O)N[C@H]1C[C@@H](n2cnc3c(Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O.NCC(c1ccc(O)cc1)c1ccc(O)cc1>>CC(=O)OCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccc(O)cc4)c4ccc(O)cc4)nc(Cl)nc32)[C@H](O)[C@@H]1O -US07790727B2,6,COc1ccc(NS(=O)(=O)c2cccc(OC(F)F)c2)cc1N1CCN(C(=O)OC(C)(C)C)CC1>>COc1ccc(NS(=O)(=O)c2cccc(OC(F)F)c2)cc1N1CCNCC1 -US20140010783A1,9,Nc1cc(F)c(Br)c(Cl)c1.S=C(Cl)Cl>>Fc1cc(N=C=S)cc(Cl)c1Br -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.O=C(c1ccc(Br)cc1)N1CCOCC1>>CC(C)(C)OC(=O)COc1ccc(Cl)cc1C#Cc1ccc(C(=O)N2CCOCC2)cc1 -US04968819,1,CI.Cc1cc(O)cc2c1C(=O)CC(C)(C)O2>>COc1cc(C)c2c(c1)OC(C)(C)CC2=O -US20110009426A1,3,COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)c(-c2ccc(Cl)c(OCc3ccc(OC)cc3)c2)n1.Cc1cnc(Br)c(Cl)c1>>COC(=O)c1ccc(-c2ncc(C)cc2Cl)c(-c2ccc(Cl)c(OCc3ccc(OC)cc3)c2)n1 -US08969375B2,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Cc1ccc(S(=O)(=O)n2c(I)cc3c(Br)ccnc32)cc1>>Cc1ccc(S(=O)(=O)n2c(C3=CCN(C(=O)OC(C)(C)C)CC3)cc3c(Br)ccnc32)cc1 -US20110301211A1,3,CCOC(=O)C(C)(C)c1ccc(Br)cc1.Cc1noc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c1NC(=O)OC(C)c1ccccc1F>>CCOC(=O)C(C)(C)c1ccc(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3F)cc2)cc1 -US05206235,1,CC(C)(CC(=O)N[C@@H]1CCc2ccccc2NC1=O)NC(=O)OC(C)(C)C.N#Cc1ccccc1-c1ccc(CBr)cc1>>CC(C)(CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3C#N)cc2)C1=O)NC(=O)OC(C)(C)C -US06777418B2,3,C[SiH](C)OC(CCc1cc2c(cc1Br)C(C)(C)CCC2(C)C)C(C)(C)C.O=CN1CCCCC1>>C[SiH](C)OC(CCc1cc2c(cc1C=O)C(C)(C)CCC2(C)C)C(C)(C)C -US20120178755A1,2,COC(=O)c1nc(C#N)c2c(Oc3ccccc3)cccc2c1O.NCC(=O)O>>N#Cc1nc(C(=O)NCC(=O)O)c(O)c2cccc(Oc3ccccc3)c12 -US20150080362A1,1,C1=COCCC1.CCCC(=O)c1ccc(N2CC(O)C2)cc1>>CCCC(=O)c1ccc(N2CC(OC3CCCCO3)C2)cc1 -US07795262B2,2,C1CCNC1.O=C(O)c1ccc2c(c1)CCN(CC(=O)N1CCN(C3CCC3)CC1)C2>>O=C(CN1CCc2cc(C(=O)N3CCCC3)ccc2C1)N1CCN(C2CCC2)CC1 -US06734180B1,1,NC1Cc2ccccc2C1.Oc1ncnc2ccsc12>>c1ccc2c(c1)CC(Nc1ncnc3ccsc13)C2 -US20110015408A1,6,COC(=O)[C@]1(C)[C@H](O)CCN1S(=O)(=O)Nc1ccc(C#N)c(Cl)c1C>>Cc1c(NS(=O)(=O)N2CC[C@@H](O)[C@@]2(C)C(=O)O)ccc(C#N)c1Cl -US20150018343A1,6,CC(C)(C)OC(=O)N1Cc2nn3cc(Br)cnc3c2C1>>Brc1cnc2c3c(nn2c1)CNC3 -US20140171430A1,2,CCOc1ccc(C)nc1C(=O)O.Cc1cc(C)nc(N2CC3CNCC3C2)n1>>CCOc1ccc(C)nc1C(=O)N1CC2CN(c3nc(C)cc(C)n3)CC2C1 -US20120010184A1,2,CC(C)(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)c1nnc(N)s1.CC(C)(SC[C@H]1CCCCO1)C(=O)O>>CC(C)(SC[C@H]1CCCCO1)C(=O)Nc1nnc(C(C)(C)CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)s1 -US20070293492A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc2ncccc2c1Br>>CC(C)(C)OC(=O)Nc1ccc2ncccc2c1Br -US05166214,2,CCCCN.O=C(O)CCCCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>CCCCNC(=O)CCCCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 -US20050197350A1,1,Cc1cnc(Cl)nc1N(C)C.NC1CCC(C(=O)O)CC1>>Cc1cnc(N[C@H]2CC[C@@H](C(=O)O)CC2)nc1N(C)C -US08476253B2,1,C=O.CCOC(=O)CCNc1ccc(C(=O)N(C)CCCN(C)C(=O)OC(C)(C)C)cc1>>CCOC(=O)CCN(C)c1ccc(C(=O)N(C)CCCN(C)C(=O)OC(C)(C)C)cc1 -US20060229302A1,1,CCc1c[nH]c2c(NS(=O)(=O)CCl)cc(C(=O)OC)cc12>>CCc1cn2c3c(cc(C(=O)OC)cc13)NS(=O)(=O)C2 -US07351700B2,8,CCCCCCSc1nc(C)cc(C(C)O)n1>>CCCCCCSc1nc(C)cc(C(C)=O)n1 -US20040116465A1,2,CCOc1ccc(Cc2nc3cc(NC)cnc3n2CC2CC2)cc1.O=S(=O)(Cl)c1cccs1>>CCOc1ccc(Cc2nc3cc(N(C)S(=O)(=O)c4cccs4)cnc3n2CC2CC2)cc1 -US20150011562A1,3,Cc1ccccc1N1CCN(c2cc(Cl)c(C(=O)NCCCN3CCCC3=O)cc2[N+](=O)[O-])CC1.OB(O)C1CC1>>Cc1ccccc1N1CCN(c2cc(C3CC3)c(C(=O)NCCCN3CCCC3=O)cc2[N+](=O)[O-])CC1 -US20100144755A1,2,CC(C)CN.CCN(CC)CCCNc1nc(-c2cc(C(=O)O)ccc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1>>CCN(CC)CCCNc1nc(-c2cc(C(=O)NCC(C)C)ccc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1 -US07511133B2,2,C1CCNCC1.CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1>>CC(=O)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 -US20100168136A1,6,Cc1cc(C(N)=O)ncc1C(SCCC1(C)OCCO1)c1c(F)ccc(F)c1F>>CC(=O)CCSC(c1cnc(C(N)=O)cc1C)c1c(F)ccc(F)c1F -US04797498,2,CCCN(CC(O)COc1ccc2c(=O)cc(-c3ccccc3)oc2c1)C(=O)OCc1ccccc1.O=C(Cl)C(c1ccccc1)c1ccccc1>>CCCN(CC(COc1ccc2c(=O)cc(-c3ccccc3)oc2c1)OC(=O)C(c1ccccc1)c1ccccc1)C(=O)OCc1ccccc1 -US20130045962A1,2,Cc1nc(NN)c(F)c(N2CCN(C)[C@@H](C)C2)n1.O=CN(C[C@@H](CC1CCCC1)C(=O)O)OCc1ccccc1>>Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c(F)c(N2CCN(C)[C@@H](C)C2)n1 -US20090105258A1,7,Cc1cc(C#N)cc(I)c1N>>Cc1cc(CN)cc(I)c1N -US04670043,4,CC(=O)C1CCCCC1=O.CC(C)Oc1cc(NN)c(F)cc1Cl>>Cc1c2c(nn1-c1cc(OC(C)C)c(Cl)cc1F)CCCC2 -US08486964B2,3,CC(C)(C)OC(=O)N1CC=C(c2c[nH]c3ncccc23)C1.ICI>>CC(C)(C)OC(=O)N1CC2CC2(c2c[nH]c3ncccc23)C1 -US20100317663A1,1,CNC(=O)c1ccccc1Nc1cc(Cl)ncc1Br.Nc1ccc(N2CCOCC2)cc1>>CNC(=O)c1ccccc1Nc1cc(Nc2ccc(N3CCOCC3)cc2)ncc1Br -US20080318874A1,6,COC(=O)c1ccc(Cc2ccccc2OCc2ccccc2)cc1>>COC(=O)c1ccc(Cc2ccccc2O)cc1 -US07414060B2,1,Brc1cncnc1.Cc1ccc(N)c(C(=O)Nc2ccn(C)n2)n1>>Cc1ccc(Nc2cncnc2)c(C(=O)Nc2ccn(C)n2)n1 -US08377944B2,1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)c1sc2nc(CCl)[nH]c(=O)c2c1C>>CCOC(=O)c1sc2nc(CN3CCN(C(=O)OC(C)(C)C)CC3)[nH]c(=O)c2c1C -US08138187B2,4,CC#CC1(O)CCC(c2ccccc2)(N(C)C)CC1.Nc1ncccc1I>>Cc1c(C2(O)CCC(c3ccccc3)(N(C)C)CC2)[nH]c2ncccc12 -US20050143452A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3c(F)c(F)cc(Br)c3O2)cc1.Cc1ccccc1B(O)O>>Cc1ccc(S(=O)(=O)OCC2Cc3c(F)c(F)cc(-c4ccccc4C)c3O2)cc1 -US05849765,1,C1=C(c2nc3ccccc3s2)CCNC1.N#Cc1ccc(CBr)cc1>>N#Cc1ccc(CN2CC=C(c3nc4ccccc4s3)CC2)cc1 -US20040259912A1,1,COC(=O)c1cc([N+](=O)[O-])ccc1O.OC(c1ccccc1)c1ccc(Cl)cc1Cl>>COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccccc1)c1ccc(Cl)cc1Cl -US08383827B2,3,CC1(C)OB(c2ccc(C#N)c(Cl)c2)OC1(C)C.CCS(=O)(=O)NC(c1cncc(Br)c1)C1CC1>>CCS(=O)(=O)NC(c1cncc(-c2ccc(C#N)c(Cl)c2)c1)C1CC1 -US06197791B1,6,CCOC(=O)C(Sc1ccc(OC)cc1)C(C)C>>COc1ccc(SC(C(=O)O)C(C)C)cc1 -US08822500B2,1,CC(C)N1C(=O)c2cc3nc(-c4c(Cl)cc[nH]c4=O)[nH]c3cc2C1=O.Cc1ccc(F)cc1CC(C)N>>Cc1ccc(F)cc1CC(C)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(C(C)C)C3=O -US05631280,3,C=Cc1cccc(C)c1.Nc1cccc(Br)c1>>Cc1cccc(/C=C/c2cccc(N)c2)c1 -US08501780B2,3,CS(=O)(=O)Nc1cccc(B(O)O)c1.NC(=O)c1cc(Br)cc2c(C3CCN(S(=O)(=O)CCCN4CCCC4)CC3)n[nH]c12>>CS(=O)(=O)Nc1cccc(-c2cc(C(N)=O)c3[nH]nc(C4CCN(S(=O)(=O)CCCN5CCCC5)CC4)c3c2)c1 -US20090023723A1,1,COc1cccc(N)c1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>COc1cccc(Nc2nc(Cl)ncc2[N+](=O)[O-])c1 -US20090018134A1,3,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(Cl)cc3)CCOCC2)nc(Cl)n1.O=C(Nc1ccc(B(O)O)cc1)NC1CC1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(Cl)cc3)CCOCC2)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 -US04049825,6,CC(=O)NCCOC(c1ccc(F)cc1)c1ccccc1Cl>>NCCOC(c1ccc(F)cc1)c1ccccc1Cl -US04337250,2,CC(=O)N1CCN(CCO)CC1.CS(=O)(=O)Cl>>CC(=O)N1CCN(CCOS(C)(=O)=O)CC1 -US20060025474A1,1,CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(O)c(C)c2)cc1C)CC.O=C1CCC[C@@H](CO)O1>>CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(OC[C@@H]3CCCC(=O)O3)c(C)c2)cc1C)CC -US20090023921A1,8,Cc1cc(C)n2nc(CO)nc2n1>>Cc1cc(C)n2nc(C=O)nc2n1 -US20080280892A1,6,CC(C)(C)OC(=O)NC1CCN(CC2Cn3c(=O)ccc4cccc2c43)CC1>>NC1CCN(CC2Cn3c(=O)ccc4cccc2c43)CC1 -US03950307,2,O=C(Cl)c1ccc(Cl)cc1Cl.O=C1NC(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21>>O=C(c1ccc(Cl)cc1Cl)N1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O -US20120289522A1,3,CCOC(=O)C1(c2ccccc2B2OC(C)(C)C(C)(C)O2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(O)CCCc1ccccc1>>CCOC(=O)C1(c2ccccc2-c2ccc(-c3onc(C)c3C(O)CCCc3ccccc3)cc2)CC1 -US06943183B2,2,NC1CCCC1.O=C(O)c1ccccc1S(=O)(=O)Cc1c(O[C@H](Cn2ccnc2)c2ccccc2)ccc2c1CCCC2=O>>O=C(NC1CCCC1)c1ccccc1S(=O)(=O)Cc1c(O[C@H](Cn2ccnc2)c2ccccc2)ccc2c1CCCC2=O -US04377578,7,O=[N+]([O-])c1ccccc1NCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1>>Nc1ccccc1NCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1 -US08003785B2,2,CCOc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C.CN1CCC(N)CC1>>CCOc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C -US20140336185A1,2,COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)OC(C)(C)C)Cc3ccc(C(=O)O)cc3)cc2)c(C(F)(F)F)c1.Cc1ccc(-c2ccc(C(=O)NN)cc2)cc1>>COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)OC(C)(C)C)Cc3ccc(C(=O)NNC(=O)c4ccc(-c5ccc(C)cc5)cc4)cc3)cc2)c(C(F)(F)F)c1 -US20080096861A1,1,CC(C)CC=O.CN(Cc1nc2ccccc2n1CCCN)C1CCCc2cccnc21>>CC(C)CCNCCCn1c(CN(C)C2CCCc3cccnc32)nc2ccccc21 -US20100160386A1,1,COC(=O)c1cnc(-c2cccc(F)c2F)cc1Cl.Oc1ccccc1Cl>>COC(=O)c1cnc(-c2cccc(F)c2F)cc1Oc1ccccc1Cl -US04128540,2,CCOC(=O)CN.O=C(N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)OCc1ccccc1>>CCOC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1 -US20060128790A1,9,COc1c(C)c(C)c2c(c1C)C(O)C1(CCC1)CN2c1ccc(Cl)cc1>>COc1c(C)c(C)c2c(c1C)CC1(CCC1)CN2c1ccc(Cl)cc1 -US20120225854A1,7,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2CN2C3COCC2CC(=O)C3)cc1)C(F)(F)F>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2CN2C3COCC2CC(O)C3)cc1)C(F)(F)F -US20130225620A1,7,N#Cc1cccc2[nH]cc(Cl)c12>>NCc1cccc2[nH]cc(Cl)c12 -US20100274051A1,2,Nc1cc(Cl)cc(Cl)c1.O=C(O)c1cc(F)ccc1O>>O=C(Nc1cc(Cl)cc(Cl)c1)c1cc(F)ccc1O -US08748426B2,2,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(N)cc3)ccc2C1=O.FC(F)(F)c1ccccc1N=C=S>>COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=S)Nc4ccccc4C(F)(F)F)cc3)ccc2C1=O -US06544989B2,7,Cc1nsc(NC(=O)Cc2ccc(O)c([N+](=O)[O-])c2)c1Cl>>Cc1nsc(NC(=O)Cc2ccc(O)c(N)c2)c1Cl -US06010981,3,CCOc1ccc(B(O)O)cc1.Cc1c(C(=O)c2cnn(C(C)(C)C)c2O)ccc(S(C)(=O)=O)c1I>>CCOc1ccc(-c2c(S(C)(=O)=O)ccc(C(=O)c3cnn(C(C)(C)C)c3O)c2C)cc1 -US20040122244A1,6,COc1c(C)c(Cc2ccc(OCc3ccccc3)c(C(=O)O)c2)c(OC)c(OC)c1OC>>COc1c(C)c(Cc2ccc(O)c(C(=O)O)c2)c(OC)c(OC)c1OC -US05001157,2,COc1ccc(C(=O)N=C=S)cc1.NC(=O)c1ccccc1N>>COc1ccc(C(=O)NC(=S)Nc2ccccc2C(N)=O)cc1 -US05098900,1,CCCn1ncc(Cl)c(Cl)c1=O.COc1ccc(CN)cc1OC>>CCCn1ncc(NCc2ccc(OC)c(OC)c2)c(Cl)c1=O -US20120202992A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1(C(=O)O)CCCCC1>>CC(C)(C)OC(=O)NC1(C(=O)O)CCCCC1 -US20110201628A1,1,Clc1nc(Cl)c2c(n1)CCC2.Cn1cnc(N)c1>>Cn1cnc(Nc2nc(Cl)nc3c2CCC3)c1 -US07132539B2,2,CC(C)(C)OC(=O)N[C@H](Cc1ccc(F)cc1)C(=O)O.COC(=O)C(Cc1ccc2ccccc2c1)N1CCNC(CC2CC2)C1=O>>COC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(Cc2ccc(F)cc2)NC(=O)OC(C)(C)C)C(CC2CC2)C1=O -US07067534B1,1,CCC(=O)Nc1cccc(C2CCNCC2)c1.O=C(CCCCCl)c1ccccc1Cl>>CCC(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccccc3Cl)CC2)c1 -US20100056490A1,3,CC1(C)OCc2ccc(Br)cc21.CN(C)C=O>>CC1(C)OCc2ccc(C=O)cc21 -US20140179672A1,2,CC(C)(C)OC(=O)N1CCC2C(N)CCC21.Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)O)n2c1>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NC3CCC4C3CCN4C(=O)OC(C)(C)C)n2c1 -US08158820B2,3,CN(C)S(=O)(=O)c1ccc(I)c(Cl)c1.C[C@H](Oc1ccc(C(F)(F)F)cc1B(O)O)C(=O)O>>C[C@H](Oc1ccc(C(F)(F)F)cc1-c1ccc(S(=O)(=O)N(C)C)cc1Cl)C(=O)O -US20040038962A1,2,Cc1cc(C#N)ccc1C(=O)O.c1ccc2c(c1)CCCCN2>>Cc1cc(C#N)ccc1C(=O)N1CCCCc2ccccc21 -US20080293822A1,3,ICI.OC1C=C(c2ccc3ccccc3c2)CC1>>OC1CCC2(c3ccc4ccccc4c3)CC12 -US20100130737A1,6,CCOC(=O)C1(NC(=O)Cc2ccc(OCc3ccccc3)cc2)Cc2ccc(-c3ccc(Cl)cc3)cc2C1>>O=C(Cc1ccc(OCc2ccccc2)cc1)NC1(C(=O)O)Cc2ccc(-c3ccc(Cl)cc3)cc2C1 -US20140336175A1,1,CCCC[C@H](C)O.Nc1nc(F)nc2c1ncn2C1CCCCO1>>CCCC[C@H](C)Oc1nc(N)c2ncn(C3CCCCO3)c2n1 -US20090156572A1,2,CC(=O)N1CCC(C(=O)O)CC1.CCN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1>>CCN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(C(=O)C2CCN(C(C)=O)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US20110077426A1,9,ClP(c1ccccc1)c1ccccc1>>c1ccc(Pc2ccccc2)cc1 -US20020183285A1,6,CCOC(=O)c1ccc(C#Cc2ccc(C3(N(Cc4ccccc4)Cc4ccccc4)CC3)cc2)cc1>>O=C(O)c1ccc(C#Cc2ccc(C3(N(Cc4ccccc4)Cc4ccccc4)CC3)cc2)cc1 -US20090124598A1,2,CC(=O)N1CCCC(C(=O)Cl)C1.CNCc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1>>CC(=O)N1CCCC(C(=O)N(C)Cc2ccc(C(=O)N3CC4(C)CC3CC(C)(C)C4)cc2)C1 -US20140296252A1,1,CCOC(=N)CCOC.CCOC(=O)Cl>>CCOC(=O)N=C(CCOC)OCC -US20130225552A1,7,CC(C)(C)OC(=O)N[C@@H]1C[C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)C1>>CC(C)(C)OC(=O)N[C@H]1C[C@H](O)C1 -US20100120784A1,6,CCOC(=O)Cn1nnc(-c2cc(OCCCCOc3cc(F)ccc3Br)no2)n1>>O=C(O)Cn1nnc(-c2cc(OCCCCOc3cc(F)ccc3Br)no2)n1 -US20040152896A1,1,C=O.CCCNC(=O)c1ccc(NC(CN2CCC(OC(=O)c3ccccc3)C2)c2ccccc2)cc1>>CCCNC(=O)c1ccc(N(C)C(CN2CCC(OC(=O)c3ccccc3)C2)c2ccccc2)cc1 -US06825181B1,6,COC(=O)c1ccc(C(=O)N2CCCC2)cc1>>O=C(O)c1ccc(C(=O)N2CCCC2)cc1 -US04543257,2,CC(=O)Cl.CC(O)CC1CC(=O)N1[Si](C)(C)C(C)(C)C>>CC(=O)OC(C)CC1CC(=O)N1[Si](C)(C)C(C)(C)C -US07932281B2,6,CCCN(CCC)CCCCN(CCC(=O)OC)Cc1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1>>CCCN(CCC)CCCCN(CCC(=O)O)Cc1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1 -US20080293782A1,1,COC(=O)CBr.Nc1cc(CN(Cc2ccccc2)C(=O)OCc2ccccc2)ccc1OCc1ccccc1>>COC(=O)CNc1cc(CN(Cc2ccccc2)C(=O)OCc2ccccc2)ccc1OCc1ccccc1 -US20050080024A1,7,C(=Cc1ccccc1)c1ccccc1>>C1=CCC(C=Cc2ccccc2)C=C1 -US07192943B2,2,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O.Cn1ncc(N)c1N>>Cn1ncc(NC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)OCc2ccccc2)c1N -US07652015B2,1,Cc1nc(Cl)ccc1[N+](=O)[O-].O=C(c1c(F)cccc1F)N1CCNCC1>>Cc1nc(N2CCN(C(=O)c3c(F)cccc3F)CC2)ccc1[N+](=O)[O-] -US20010020095A1,7,O=C(O)C1CCc2ccccc21>>OCC1CCc2ccccc21 -US20110086854A1,6,COC(=O)c1ccc(NC(=O)N2C[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1>>CC(C)(C)C[C@@H]1CN(C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20040209886A1,1,CC(C)(Oc1ccccc1Oc1ccc(N)cc1)C(=O)NCCO.CCOC(=O)c1cn2ncc(C#N)c(Cl)c2c1C>>CCOC(=O)c1cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4OC(C)(C)C(=O)NCCO)cc3)c2c1C -US08802864B2,2,NNC(=O)C[C@@H]1CCN(C(=O)C2CC2)C1.O=C=Nc1ccc(Br)cc1C(F)(F)F>>O=C(C[C@@H]1CCN(C(=O)C2CC2)C1)NNC(=O)Nc1ccc(Br)cc1C(F)(F)F -US07390835B2,1,C[C@H](N)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1.N#CCC(=O)c1cc(F)cc(F)c1>>C[C@H](NC(CC#N)c1cc(F)cc(F)c1)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1 -US04091107,6,CCCCCC(CCCN1C(=O)c2ccccc2C1=O)OC1CCCCO1>>CCCCCC(CCCN)OC1CCCCO1 -US05550257,3,C#CCN1CC[C@@H](OCOC)C1=O.C=O.CNC>>COCO[C@@H]1CCN(CC#CCN(C)C)C1=O -US20110212968A1,1,CCC=O.COc1ccc(CCNCc2ccccc2)cc1OC>>CCCN(CCc1ccc(OC)c(OC)c1)Cc1ccccc1 -US07973047B2,7,O=Cc1ccc(F)c(Br)c1>>OCc1ccc(F)c(Br)c1 -US20090318448A1,1,CC(C)(C)c1ccc2c(=O)[nH]ncc2c1.O=Cc1c(Br)cccc1Br>>CC(C)(C)c1ccc2c(=O)n(-c3cccc(Br)c3C=O)ncc2c1 -US07947706B2,2,Cc1ccc(N=C=O)cc1.NC(=O)c1[nH]c2ncccc2c1-c1ccc(N)cc1>>Cc1ccc(NC(=O)Nc2ccc(-c3c(C(N)=O)[nH]c4ncccc34)cc2)cc1 -US03939178,6,COC(=O)CC1(C)SCCc2c1[nH]c1ccccc21>>CC1(CC(=O)O)SCCc2c1[nH]c1ccccc21 -US08329682B2,3,COc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1.Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2>>COc1ccc(-c2ccc3c(c2)/C(=C/c2[nH]c4c(c2C)C(=O)N(CCN2CCCCC2)CCC4)C(=O)N3)cc1 -US06271403B1,1,BrCc1ccccc1.C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCO)[C@H]3[C@@H]1C=CC21OCCO1>>C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4C[C@@H](CCCCCO)[C@H]3[C@@H]1C=CC21OCCO1 -US05366972,1,CCNc1ncccc1C(=O)Nc1c(C)cc(OC)nc1Br>>CCN1c2ncccc2C(=O)Nc2c(C)cc(OC)nc21 -US20130231354A1,1,Fc1ccc(-n2ncc3c(I)ccnc32)cc1.c1c[nH]cn1>>Fc1ccc(-n2ncc3c(-n4ccnc4)ccnc32)cc1 -US08486967B2,1,CO[C@H]1CNCC[C@H]1Nc1nc2c(-c3ccc(F)c(F)c3)cccn2n1.Cc1cc(Cl)ncn1>>CO[C@H]1CN(c2cc(C)ncn2)CC[C@H]1Nc1nc2c(-c3ccc(F)c(F)c3)cccn2n1 -US20050239789A1,1,CCOC(=O)C(C)=O.NNc1cccc(Cl)c1F>>CCOC(=O)C(C)=NNc1cccc(Cl)c1F -US08686048B2,3,CC(C)COc1cccc(B(O)O)c1.Nc1c(F)cc(Br)cc1F>>CC(C)COc1cccc(-c2cc(F)c(N)c(F)c2)c1 -US20110319378A1,2,C=CC(=O)Cl.C=C[C@H](c1cccc(Cl)c1)[C@H](NC(C1CC1)C1CC1)c1ccc(Cl)cc1>>C=CC(=O)N(C(C1CC1)C1CC1)[C@H](c1ccc(Cl)cc1)[C@H](C=C)c1cccc(Cl)c1 -US08772325B2,6,CC(NC(=O)OCc1ccccc1)c1nc(-c2ccccc2)c[nH]1>>CC(N)c1nc(-c2ccccc2)c[nH]1 -US20070003680A1,7,COC(=O)c1cncc(Br)c1>>OCc1cncc(Br)c1 -US07435815B2,2,COc1ccccc1N.Cc1ccccc1S(=O)(=O)Cl>>COc1ccccc1NS(=O)(=O)c1ccccc1C -US07847100B2,2,CC(C)(C)OC(=O)N[C@](C)(Cc1ccccc1)c1nnc(-c2cc(C(=O)O)cc(C3(C#N)CCCC3)c2)o1.C[C@@H](N)c1ccc(F)cc1>>C[C@@H](NC(=O)c1cc(-c2nnc([C@@](C)(Cc3ccccc3)NC(=O)OC(C)(C)C)o2)cc(C2(C#N)CCCC2)c1)c1ccc(F)cc1 -US20070049537A1,7,CC(=O)OC[C@H]1O[C@](O)(c2ccc(Cl)c(Cc3ccc(OC4(C(=O)O)CCCC4)cc3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@H]1O[C@](O)(c2ccc(Cl)c(Cc3ccc(OC4(CO)CCCC4)cc3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US20110294850A1,2,CC1(C)CN(Cc2ccncc2)c2ccc(O)cc21.CCCCCCN=C=O>>CCCCCCNC(=O)Oc1ccc2c(c1)C(C)(C)CN2Cc1ccncc1 -US20080287415A1,2,CC(=O)OC[C@@H](C)n1ccc2c(N)c(C)ccc2c1=O.O=C(O)CC1(O)CCCCCC1>>CC(=O)OC[C@@H](C)n1ccc2c(NC(=O)CC3(O)CCCCCC3)c(C)ccc2c1=O -US07105551B2,6,CCOC(=O)COc1ccc(OC(C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C>>Cc1cc(OC(C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O -US09050344B2,2,CSc1ncc(Br)c([C@H](N)Cc2cc(F)cc(F)c2)n1.O=C(O)Cn1nc(C(F)(F)F)c2c1CCCC2>>CSc1ncc(Br)c([C@@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)n1 -US05693651,9,Oc1ccc2cccnc2c1>>c1ccc2ncccc2c1 -US06403792B1,6,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)Nc1ccccc1>>O=C(Nc1ccccc1)[C@@H]1CCCN1 -US20080306120A1,7,CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc([N+](=O)[O-])cc2)n1>>CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(N)cc2)n1 -US08143263B2,1,Clc1ccccc1-n1ncc2c(Cl)ncnc21.NCC(=O)O>>O=C(O)CNc1ncnc2c1cnn2-c1ccccc1Cl -US06844466B2,6,CCCCCN(C(=O)C(F)(F)F)c1ccc2c(c1)C(C)(C)CCC2(C)C>>CCCCCNc1ccc2c(c1)C(C)(C)CCC2(C)C -US20070142371A1,2,COc1c(N)cc(C(C)(C)C)cc1C#N.Cc1ccc(C(=O)O)cc1N=[N+]=[N-]>>COc1c(C#N)cc(C(C)(C)C)cc1NC(=O)c1ccc(C)c(N=[N+]=[N-])c1 -US20040176405A1,2,COC(=O)CC1CCCCC(N)C1.Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Cl>>COC(=O)CC1CCCCC(NC(=O)c2c(-c3c(F)cccc3Cl)noc2C)C1 -US04377531,2,CC(C)C(C(=O)Cl)c1ccc(OC(F)F)cc1.N#CC(O)c1cccc(Oc2ccccc2)c1>>CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c1ccc(OC(F)F)cc1 -US20150133428A1,6,CC(C)(C)OC(=O)N1Cc2c(C(N)=O)c(-c3ccc(F)c(Cl)c3)nn2[C@H]2COC[C@H]21>>NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CN[C@@H]1COC[C@@H]12 -US20100036118A1,2,CN(C)CCN1CCNCC1.COc1ccccc1-c1n[nH]c2ncc(-c3cc(C)c(N)c(C(=O)O)c3)cc12>>COc1ccccc1-c1n[nH]c2ncc(-c3cc(C)c(N)c(C(=O)N4CCN(CCN(C)C)CC4)c3)cc12 -US09079880B2,6,COC(=O)c1cccc(OCC(=O)OC(C)(C)C)c1>>COC(=O)c1cccc(OCC(=O)O)c1 -US20100222322A1,2,NCc1nccs1.O=C(O)c1[nH]c2ccc(Br)cc2c1S(=O)(=O)N1CCCC1>>O=C(NCc1nccs1)c1[nH]c2ccc(Br)cc2c1S(=O)(=O)N1CCCC1 -US20100152160A1,6,CC(C)(C)OC(=O)N1CCC(CO)(Cc2ccc(F)cc2)CC1>>OCC1(Cc2ccc(F)cc2)CCNCC1 -US06787536B2,3,CC(C)(C)OC(=O)N1CCN(c2ccc(Br)cn2)CC1.OB(O)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3ccc(Cl)cc3)cn2)CC1 -US06432950B1,1,Cc1sc2nc(-c3cnccn3)nc(Cl)c2c1Cl.NCc1ccc(Cl)c(Cl)c1>>Cc1sc2nc(-c3cnccn3)nc(NCc3ccc(Cl)c(Cl)c3)c2c1Cl -US20120114765A1,1,COC(=O)c1cc([N+](=O)[O-])c(Cl)s1.O=C1COc2cc(O)ccc2N1>>COC(=O)c1cc([N+](=O)[O-])c(Oc2ccc3c(c2)OCC(=O)N3)s1 -US20020165241A1,6,COC(=O)C1CC1c1ccccc1F>>O=C(O)C1CC1c1ccccc1F -US20080207708A1,2,Nc1ccc(CO)cc1.O=C(O)c1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1>>O=C(Nc1ccc(CO)cc1)c1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1 -US20130045986A1,3,CC(C)(C)OC(=O)N1CCC(c2nc3cc(B4OC(C)(C)C(C)(C)O4)ccc3o2)CC1.Fc1cc(Br)ccc1-n1cnnn1>>CC(C)(C)OC(=O)N1CCC(c2nc3cc(-c4ccc(-n5cnnn5)c(F)c4)ccc3o2)CC1 -US20070129416A1,2,CCOc1cc(C(C)(C)C)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1.O=C(Cl)C1CC1>>CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)C1CC1 -US07094789B2,3,CC(C)(C)OC(=O)N1CCC(Nc2cccc3cncc(Br)c23)CC1.C[Sn](C)(C)C>>Cc1cncc2cccc(NC3CCN(C(=O)OC(C)(C)C)CC3)c12 -US20070232590A1,1,O=C1CCCC1.O=C1CCCN1c1cnc(Oc2ccc3c(c2)CCNCC3)cn1>>O=C1CCCN1c1cnc(Oc2ccc3c(c2)CCN(C2CCCC2)CC3)cn1 -US06432993B1,1,CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-].Oc1ccc(-c2ccc(OCc3ccccc3)cc2)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-c3ccc(OCc4ccccc4)cc3)cc2)ccc1[N+](=O)[O-] -US04753941,2,Nc1ccc2ccc(Oc3ccccc3)nc2n1.O=C(O)C1=CSCCS1>>O=C(Nc1ccc2ccc(Oc3ccccc3)nc2n1)C1=CSCCS1 -US20090181963A1,2,CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)O)cc4)cc3)nc21.CN(C)CCN>>CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)NCCN(C)C)cc4)cc3)nc21 -US20110028467A1,2,O=C(O)c1cc(O)nc(O)n1.c1cc2c(cn1)NCCO2>>O=C(c1cc(O)nc(O)n1)N1CCOc2ccncc21 -US07989438B2,7,C=CCc1cccc(-c2[nH]c3cc(C(=O)OC)ccc3c2C2CCCCC2)c1O>>CCCc1cccc(-c2[nH]c3cc(C(=O)OC)ccc3c2C2CCCCC2)c1O -US20100234620A1,1,CN(C)CCC(O)c1cccs1.Fc1cccc2ccccc12>>CN(C)CCC(Oc1cccc2ccccc12)c1cccs1 -US20050131014A1,1,Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=Cc1cc(F)ccc1C(F)(F)F>>Fc1ccc(C(F)(F)F)c(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 -US07638648B2,3,C#Cc1cc(O)c2c(c1)C(C)(C)CCC2=O.COC(=O)Cc1ccc(I)cc1>>COC(=O)Cc1ccc(C#Cc2cc(O)c3c(c2)C(C)(C)CCC3=O)cc1 -US20060160794A1,1,CC(C)Br.Nc1ccc(Cl)cc1Cl>>CC(C)Nc1ccc(Cl)cc1Cl -US05179105,7,COCOc1ccc(C=CC(=O)OC)cc1[N+](=O)[O-]>>COCOc1ccc(C=CCO)cc1[N+](=O)[O-] -US20150232480A1,3,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cc3nc(-c4cccc(Br)c4)cn23)CC1.C=CC[C@H](C)Oc1ccc(F)cc1B(O)O>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cc3nc(-c4cccc(-c5cc(F)ccc5O[C@@H](C)CC=C)c4)cn23)CC1 -US07968570B2,1,O=C1c2c(Cl)cc(Br)cc2CN1Cc1ccc(Cl)cc1.OCC(F)F>>O=C1c2c(Cl)cc(OCC(F)F)cc2CN1Cc1ccc(Cl)cc1 -US20110230428A1,6,CON=C(CCC(=O)NC1CCN(C(=O)OC(C)(C)C)C1)c1ccc(Cl)c(Cl)c1>>CON=C(CCC(=O)NC1CCNC1)c1ccc(Cl)c(Cl)c1 -US04851535,2,COC(=O)c1cc(F)c(O)nc1Nc1ccc(F)cc1F.Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1>>COC(=O)c1cc(F)c(OS(=O)(=O)c2c(C)cc(C)cc2C)nc1Nc1ccc(F)cc1F -US20120015950A1,7,CC1(CC#N)CCN(C(=O)OC(C)(C)C)CC1>>CC1(CCN)CCN(C(=O)OC(C)(C)C)CC1 -US20150225394A1,6,C=CCOC(=O)N(CC1CCN(C(=O)OC(C)(C)C)CC1)[C@@H]1C[C@H]1c1ccccc1>>C=CCOC(=O)N(CC1CCNCC1)[C@@H]1C[C@H]1c1ccccc1 -US20070179126A1,2,CC(C)(C)OC(=O)N1CCC[C@@H](CO)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC[C@@H](COS(C)(=O)=O)C1 -US20100069360A1,3,COCc1[nH]c2c(ccc3cnc(Cl)cc32)c1C(=O)OC(C)(C)C.OB(O)/C=C/c1ccccc1>>COCc1[nH]c2c(ccc3cnc(/C=C/c4ccccc4)cc32)c1C(=O)OC(C)(C)C -US07671043B2,7,CCOC(=O)c1cnc(-c2noc(-c3ccc(CC(C)C)cc3)n2)cn1>>CC(C)Cc1ccc(-c2nc(-c3cnc(CO)cn3)no2)cc1 -US20130210796A1,1,CC1(C)COCCN1.N#Cc1ccc(-n2nnnc2CCl)cc1>>CC1(C)COCCN1Cc1nnnn1-c1ccc(C#N)cc1 -US20070123532A1,2,CC(C)(O)[C@@H]1C[C@@H](O)CN1Cc1ccccc1.CS(=O)(=O)Cl>>CC(C)(O)[C@@H]1C[C@@H](OS(C)(=O)=O)CN1Cc1ccccc1 -US20090227579A1,1,N#Cc1nc(N2CCCCC2)c2c(n1)N(CCO)CCN2.O=C1NC(=O)c2ccccc21>>N#Cc1nc(N2CCCCC2)c2c(n1)N(CCN1C(=O)c3ccccc3C1=O)CCN2 -US08026257B2,6,C[Si](C)(C)C#Cc1c(N)cc(C(F)(F)F)cc1Br>>C#Cc1c(N)cc(C(F)(F)F)cc1Br -US05798316,4,Nc1ccc(O)cc1F.O=C1OC(=O)C2=C1CCCC2>>O=C1C2=C(CCCC2)C(=O)N1c1ccc(O)cc1F -US07732446B1,6,CCOC(=O)c1csc(Nc2cnc(CNC(=O)OC(C)(C)C)c3cc(OC)c(OC)cc23)n1>>CCOC(=O)c1csc(Nc2cnc(CN)c3cc(OC)c(OC)cc23)n1 -US20120122931A1,6,CCOC(=O)c1cccc(Cc2c(-c3ccsc3)[nH]c3cc(OC)ccc23)n1>>COc1ccc2c(Cc3cccc(C(=O)O)n3)c(-c3ccsc3)[nH]c2c1 -US20110301356A1,1,Nc1ccccc1Cl.O=Cc1ccccc1>>Clc1ccccc1N=Cc1ccccc1 -US07592477B2,3,C#Cc1ccc(CCC)cc1.CCOC(=O)C(=O)N(Cc1ccc(C(F)(F)F)cc1)Cc1ccc2occ(Br)c2c1>>CCCc1ccc(C#Cc2coc3ccc(CN(Cc4ccc(C(F)(F)F)cc4)C(=O)C(=O)OCC)cc23)cc1 -US05624926,1,COc1cc2ncnc(N3CCC(n4c(=O)[nH]c5ccc([N+](=O)[O-])cc5c4=O)CC3)c2cc1OC.Clc1cccc(Cl)c1CBr>>COc1cc2ncnc(N3CCC(n4c(=O)c5cc([N+](=O)[O-])ccc5n(Cc5c(Cl)cccc5Cl)c4=O)CC3)c2cc1OC -US05750549,2,COC(=O)[C@H]1CC[C@H](NCc2ccc(OC)cc2)[C@@H]1c1ccc(F)cc1.O=C(Cl)OCc1ccccc1>>COC(=O)[C@H]1CC[C@H](N(Cc2ccc(OC)cc2)C(=O)OCc2ccccc2)[C@@H]1c1ccc(F)cc1 -US20110082210A1,2,CC(C)(Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1)C(=O)NCCOCCN.CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCOCCNC(=O)C(C)(C)Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1 -US06723722B1,6,CC(C)(C)OC(=O)NN1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1=O>>NN1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1=O -US20100137313A1,4,COCCCNc1nc(Nc2ccc(F)c(Cl)c2)ncc1C(N)=S.O=C(CBr)c1cccnc1>>COCCCNc1nc(Nc2ccc(F)c(Cl)c2)ncc1-c1nc(-c2cccnc2)cs1 -US07473699B2,9,[N-]=[N+]=NC[C@H]1CN(c2ccc(C3=CCN(Cc4ccccc4)CC3)c(F)c2)C(=O)O1>>NC[C@H]1CN(c2ccc(C3=CCN(Cc4ccccc4)CC3)c(F)c2)C(=O)O1 -US20150218150A1,3,CC(C)(C)OC(=O)Nc1cncc(B2OC(C)(C)C(C)(C)O2)c1.O=C1Cc2cc(-c3ccc(I)s3)ccc2N1>>CC(C)(C)OC(=O)Nc1cncc(-c2ccc(-c3ccc4c(c3)CC(=O)N4)s2)c1 -US07745665B2,6,CNCC(O)c1cccc(OCOC)c1>>CNCC(O)c1cccc(O)c1 -US05719317,9,CC(C)(C(=O)O)c1ccc(Cl)c([N+](=O)[O-])c1>>CC(C)(C(=O)O)c1cccc([N+](=O)[O-])c1 -US20100204196A1,6,COc1cc2c(cc1[N+](=O)[O-])N(C(C)=O)CC2>>COc1cc2c(cc1[N+](=O)[O-])NCC2 -US06632816B1,2,CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](N)Cc1ccc2ccccc2c1)S(=O)(=O)c1ccc(F)c(N)c1.O=C(O)c1cccnc1>>CC(C)CN(C(CO)CCCCNC(=O)C(Cc1ccc2ccccc2c1)NC(=O)c1cccnc1)S(=O)(=O)c1ccc(F)c(N)c1 -US20150210682A1,1,CCCc1ccccc1O.CI>>CCCc1ccccc1OC -US07888352B2,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.C[C@H](O)C(=O)N1CCN(Cc2cc3c(N4CCOCC4)nc(Cl)nc3s2)CC1>>C[C@H](O)C(=O)N1CCN(Cc2cc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3s2)CC1 -US05190971,1,C1=COCCC1.CCOC(=S)Sc1ccc(C)cc1CO>>CCOC(=S)Sc1ccc(C)cc1COC1CCCCO1 -US04988828,5,O=Cc1cccc(OCCCN2C(=O)c3ccccc3C2=O)c1.OCCO>>O=C1c2ccccc2C(=O)N1CCCOc1cccc(C2OCCO2)c1 -US20060009461A1,1,N#Cc1cccnc1N1CCNCC1.O=C(CCl)Nc1cccc([N+](=O)[O-])c1>>N#Cc1cccnc1N1CCN(CC(=O)Nc2cccc([N+](=O)[O-])c2)CC1 -US20090247628A1,2,CCN(CC)CC#CCO.O=C(O)C(O)(c1ccccc1)C1CCCCC1>>CCN(CC)CC#CCOC(=O)C(O)(c1ccccc1)C1CCCCC1 -US06605626B2,6,COc1ccc(C(=O)Nc2ccccc2NC(=O)OCCC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>COc1ccc(C(=O)Nc2ccccc2NC(=O)OCCC2CCNCC2)cc1 -US20150274740A1,6,CC(=O)n1ncc2cc(-c3cc(=O)n4nc(C)nc4[nH]3)ccc21>>Cc1nc2[nH]c(-c3ccc4[nH]ncc4c3)cc(=O)n2n1 -US20100298325A1,1,Fc1ccc(Oc2ccc(Cl)nc2)cc1F.Nc1cccc(N2CCOCC2)c1>>Fc1ccc(Oc2ccc(Nc3cccc(N4CCOCC4)c3)nc2)cc1F -US07368461B2,2,CNC[C@@H](CCN1CCC(N2CCCCC2=O)CC1)c1ccc(Cl)c(Cl)c1.O=C(Cl)c1ccccc1F>>CN(C[C@@H](CCN1CCC(N2CCCCC2=O)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1F -US20120094997A1,1,COC(=O)c1ccc2ccn(CC=O)c(=O)c2c1.Nc1cccc(-n2cccn2)c1>>COC(=O)c1ccc2ccn(CCNc3cccc(-n4cccn4)c3)c(=O)c2c1 -US20150030704A1,3,C#Cc1cc(OCc2ccccc2)c(OCc2ccccc2)nn1.FC(F)Oc1cccc(I)c1>>FC(F)Oc1cccc(C#Cc2cc(OCc3ccccc3)c(OCc3ccccc3)nn2)c1 -US08835469B2,1,COC(=O)c1cc(O)cc(OC2CCN(C)C2=O)c1.Cc1nnc(-c2ccc(I)cc2)o1>>COC(=O)c1cc(Oc2ccc(-c3nnc(C)o3)cc2)cc(OC2CCN(C)C2=O)c1 -US05565485,6,COC(=O)c1ccc(OC(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)c(CC(C)C)c1>>CC(C)Cc1cc(C(=O)O)ccc1OC(C(=O)NS(=O)(=O)c1ccc(C(C)C)cc1)c1ccc2c(c1)OCO2 -US20090247567A1,2,C1COCCN1.O=C([O-])c1cc2c(s1)-c1cc(F)ccc1OC2>>O=C(c1cc2c(s1)-c1cc(F)ccc1OC2)N1CCOCC1 -US08486950B2,6,COC(=O)c1c(Cl)cc(NC(=O)OC(C)(C)C)cc1Cl>>COC(=O)c1c(Cl)cc(N)cc1Cl -US20140148478A1,4,CCOC(=O)CC(=O)Nc1cc(C(F)(F)F)cnc1C(C)=O>>CCOC(=O)c1c(O)nc2cc(C(F)(F)F)cnc2c1C -US20120302573A1,4,NC(=S)Nc1ccc(Br)nc1.O=C(CBr)c1cccnc1>>Brc1ccc(Nc2nc(-c3cccnc3)cs2)cn1 -US20050119317A1,1,C1COCCN1.Fc1ccc(C2=NOC(Cn3ccnn3)C2)cc1F>>Fc1cc(C2=NOC(Cn3ccnn3)C2)ccc1N1CCOCC1 -US07618970B2,1,COC1COCCC1=O.N[C@@H]1CC[C@@](C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)([C@H]2CCOC2)C1>>COC1COCC[C@H]1N[C@@H]1CC[C@@](C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)([C@H]2CCOC2)C1 -US05972951,2,CC(=O)c1ccc(-c2ccc(C(=O)O)cc2)c(C)c1.CN1CCC2(CC1)COc1cc3c(cc12)NCC3>>CC(=O)c1ccc(-c2ccc(C(=O)N3CCc4cc5c(cc43)C3(CCN(C)CC3)CO5)cc2)c(C)c1 -US20050137236A1,9,CC(C)Nc1cc(-c2ccc(CCN(C[C@H](O)c3ccc(Cl)nc3)C(=O)OC(C)(C)C)cc2)ccc1C(=O)NS(C)(=O)=O>>CC(C)Nc1cc(-c2ccc(CCN(C[C@H](O)c3cccnc3)C(=O)OC(C)(C)C)cc2)ccc1C(=O)NS(C)(=O)=O -US05153214,2,COC(=O)CCC(CCCCN)c1cccc(-c2cccnc2)c1.O=S(=O)(Cl)c1ccc(F)cc1>>COC(=O)CCC(CCCCNS(=O)(=O)c1ccc(F)cc1)c1cccc(-c2cccnc2)c1 -US06936608B2,7,O=[N+]([O-])c1ccc(F)c(-c2ccnc(Cl)n2)c1>>Nc1ccc(F)c(-c2ccnc(Cl)n2)c1 -US20150038438A1,2,CNOC.O=C(O)Cc1ccc2c(c1)OCO2>>CON(C)C(=O)Cc1ccc2c(c1)OCO2 -US07285563B2,2,CCOC(=O)C(OCC)OCC.NCc1ccccc1Br>>CCOC(OCC)C(=O)NCc1ccccc1Br -US20150025070A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1cccs1>>CC(C)(C)OC(=O)NCc1cccs1 -US05962501,4,N#Cc1ccc(NN)cc1.O=C1CCC(OC(=O)c2ccccc2)CC1>>N#Cc1ccc2[nH]c3c(c2c1)CC(OC(=O)c1ccccc1)CC3 -US09108936B2,2,COc1cc(Br)cc(F)c1C(=O)O.NCc1ccc(Cl)cc1>>COc1cc(Br)cc(F)c1C(=O)NCc1ccc(Cl)cc1 -US20130266645A1,9,COc1ccc2c(c1)CC[C@H]1[C@@H]3C[C@H](N=[N+]=[N-])C[C@@]3(C)CC[C@H]21>>COc1ccc2c(c1)CC[C@H]1[C@@H]3C[C@H](N)C[C@@]3(C)CC[C@H]21 -US20100278833A1,1,COC(=O)c1sc(-n2cnc3cnccc32)cc1O.FC(F)Oc1ccccc1CBr>>COC(=O)c1sc(-n2cnc3cnccc32)cc1OCc1ccccc1OC(F)F -US20040102517A1,3,CCOP(=O)(Cc1cc(OC)c(C(C)C)c(OC)c1)OCC.O=Cc1ccco1>>COc1cc(C=Cc2ccco2)cc(OC)c1C(C)C -US20120202794A1,2,CC(C)CC1CNC(=O)[C@H](CC(C)C)NC1.O=C(O)c1cc(-c2ccc(F)cc2)on1>>CC(C)CC1CNC(=O)[C@H](CC(C)C)N(C(=O)c2cc(-c3ccc(F)cc3)on2)C1 -US20100168105A1,1,FC(F)(F)c1ccc(Cl)nc1.O=C(C1CC12CCNCC2)N1CCN(C2CCCCC2)CC1>>O=C(C1CC12CCN(c1ccc(C(F)(F)F)cn1)CC2)N1CCN(C2CCCCC2)CC1 -US06960586B2,2,CC(C)NC(C)C.O=C(Cl)c1ccc2cc(Br)ccc2c1>>CC(C)N(C(=O)c1ccc2cc(Br)ccc2c1)C(C)C -US20040198737A1,1,BrCCCn1cc(-c2cc3nccnc3[nH]2)c2ccccc21.C1COCCN1>>c1ccc2c(c1)c(-c1cc3nccnc3[nH]1)cn2CCCN1CCOCC1 -US20060004017A1,1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.Cc1cc2c(F)c(O)ccc2[nH]1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCC1CCN(C)CC1 -US20150218156A1,2,COC(=O)C(=O)Cl.NC(=S)N(N)CCc1ccccc1>>COC(=O)C(=O)NN(CCc1ccccc1)C(N)=S -US20150175563A1,10,CCOC(=O)c1sc(N2CCOCC2)nc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1sc(N2CCOCC2)nc1CBr -US08536187B2,9,COc1ccc(Br)cc1S(=O)(=O)Cl>>COc1ccc(Br)cc1S(=O)[O-] -US20120071514A1,1,CCO.Cn1c(=O)oc2ccc(-c3cncc(CNCc4ccccc4)c3)cc21>>CCN(Cc1ccccc1)Cc1cncc(-c2ccc3oc(=O)n(C)c3c2)c1 -US07005440B1,1,ClCc1cccc(OCc2ccc3ccccc3n2)c1.O=Cc1ccccc1O>>O=Cc1ccccc1OCc1cccc(OCc2ccc3ccccc3n2)c1 -US20150175563A1,3,CCOC(OCC)c1ccn2nc(C)c(-c3nc(Br)c(-c4ncn(COCC[Si](C)(C)C)n4)s3)c2c1.Clc1ccc(C[Zn+])cc1>>CCOC(OCC)c1ccn2nc(C)c(-c3nc(Cc4ccc(Cl)cc4)c(-c4ncn(COCC[Si](C)(C)C)n4)s3)c2c1 -US20120232033A1,1,CC1(CO)COC1.Oc1ccc(Br)c(F)c1>>CC1(COc2ccc(Br)c(F)c2)COC1 -US05051524,6,CCCCCCCCCCCCP(=O)(O)CCCNC(=O)OCc1ccccc1>>CCCCCCCCCCCCP(=O)(O)CCCN -US06962933B1,2,Cc1cc(C)cc(-c2nc(N)sc2-c2ccncc2)c1.O=C(Cl)c1cnccn1>>Cc1cc(C)cc(-c2nc(NC(=O)c3cnccn3)sc2-c2ccncc2)c1 -US08324219B2,1,COC(=O)c1ccc(N)cc1.Clc1cnccn1>>COC(=O)c1ccc(Nc2cnccn2)cc1 -US20110053923A1,1,CSc1nc(CS(C)(=O)=O)cc(OS(=O)(=O)C(F)(F)F)n1.C[C@H]1COC[C@@H](C)N1>>CSc1nc(CS(C)(=O)=O)cc(N2[C@@H](C)COC[C@H]2C)n1 -US20080194616A1,1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.CCCCc1nc2ccccn2c(=O)c1-c1ccc(O)cc1>>CCCCc1nc2ccccn2c(=O)c1-c1ccc(O[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1 -US20090054647A1,9,CCOC(OCC)c1nc(C2CC2)nc(Cl)c1Cl.N>>CCOC(OCC)c1nc(C2CC2)nc(N)c1Cl -US03989701,2,COc1cc(C(=O)Cl)cc(OC)c1OC.Nc1cc(C(=O)c2ccccc2)ccc1N1CCOCC1>>COc1cc(C(=O)Nc2cc(C(=O)c3ccccc3)ccc2N2CCOCC2)cc(OC)c1OC -US05026856,1,Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1.c1ccc2c(c1)CNC2>>Nc1c(F)c(N2Cc3ccccc3C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1 -US20050107423A1,6,O=C(OCc1ccccc1)N1CC2CC(F)C(O)C2C1>>OC1C(F)CC2CNCC21 -US20090054508A1,1,NCCO.O=Cc1ccn(-c2ccccc2/C=C/c2n[nH]c3ccccc23)c1>>OCCNCc1ccn(-c2ccccc2/C=C/c2n[nH]c3ccccc23)c1 -US07279470B2,2,CN(C(=O)Cl)c1ccccc1.Oc1ccc(Oc2ccc(Cl)c(Cl)c2)nn1>>CN(C(=O)Oc1ccc(Oc2ccc(Cl)c(Cl)c2)nn1)c1ccccc1 -US07915443B2,2,C1COCCN1.Cc1ccoc1C(=O)Nc1cccc(C#Cc2cncc(C(=O)N=S(C)(=O)c3ccc(CCC(=O)O)cc3)c2)c1>>Cc1ccoc1C(=O)Nc1cccc(C#Cc2cncc(C(=O)N=S(C)(=O)c3ccc(CCC(=O)N4CCOCC4)cc3)c2)c1 -US07906652B2,1,Cn1nnc(-c2cc(F)cc(C(C3CNC3)C(C)(C)F)c2)n1.N#Cc1cccc(C(Br)c2ccc(Cl)cc2)c1>>Cn1nnc(-c2cc(F)cc(C(C3CN(C(c4ccc(Cl)cc4)c4cccc(C#N)c4)C3)C(C)(C)F)c2)n1 -US20090018134A1,1,C[C@H]1COCCN1c1cc(CI)nc(Cl)n1.O=S([O-])c1ccc(F)c(F)c1>>C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccc(F)c(F)c2)nc(Cl)n1 -US20120035239A1,1,CC[C@@H](C(N)=O)N1CC(CO)CC1=O.Oc1ccccc1>>CC[C@@H](C(N)=O)N1CC(COc2ccccc2)CC1=O -US04751302,1,CCN(CC)CCCBr.CCN(CC)CCCn1nc(N)c2c(Cl)cccc21>>CCN(CC)CCCNc1nn(CCCN(CC)CC)c2cccc(Cl)c12 -US20150072980A1,3,COc1cc2c(cc1N1CCOCC1)CCC2=O.O=Cc1ccc(C(F)(F)F)nc1>>COc1cc2c(cc1N1CCOCC1)C/C(=C\c1ccc(C(F)(F)F)nc1)C2=O -US20080280875A1,1,Cn1ccc(NC(=O)c2cc(O)c3c(c2)OC(C(F)F)C3)n1.O=C(c1c(F)cc(F)cc1F)N1CCC1>>Cn1ccc(NC(=O)c2cc(Oc3cc(F)c(C(=O)N4CCC4)c(F)c3)c3c(c2)OC(C(F)F)C3)n1 -US20070249670A1,2,COC(=O)C(N)CCC(C)CC(C)(C)C.Nc1cc2ccccc2cc1C(=O)O>>COC(=O)C(CCC(C)CC(C)(C)C)NC(=O)c1cc2ccccc2cc1N -US20120108568A1,2,CC(C)(N)CF.COc1ncc(F)cc1[C@H]1CCCN1c1ccn2ncc(C(=O)O)c2n1>>COc1ncc(F)cc1[C@H]1CCCN1c1ccn2ncc(C(=O)NC(C)(C)CF)c2n1 -US20130059834A1,6,Cn1nc(-c2cnc3[nH]cc(C(=O)NC(C)(C)C(=O)OC(C)(C)C)c3n2)c2ccc(F)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)NC(C)(C)C(=O)O)c3n2)c2ccc(F)cc21 -US04833146,3,CCOCn1cnc2c1c(=O)n(CCCCC(C)=O)c(=O)n2C.C[Mg+]>>CCOCn1cnc2c1c(=O)n(CCCCC(C)(C)O)c(=O)n2C -US08324186B2,1,Cc1cnn(C2CCC(=O)CC2)c1.O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CNC1>>Cc1cnn(C2CCC(N3CC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)c1 -US08648089B2,3,COc1ccc(B(O)O)cc1.O=[N+]([O-])c1cccc(-c2ccc3c(Br)cn(-c4ccncc4)c3c2)c1>>COc1ccc(-c2cn(-c3ccncc3)c3cc(-c4cccc([N+](=O)[O-])c4)ccc23)cc1 -US20120101099A1,1,COC(=O)c1cccc(CBr)c1.O=C1NC(=O)c2ccccc21>>COC(=O)c1cccc(CN2C(=O)c3ccccc3C2=O)c1 -US04424210,1,CCCCCCCCBr.O=C1CCCCCCCN1>>CCCCCCCCN1CCCCCCCC1=O -US20090111862A1,7,CN(C)S(=O)(=O)c1ccc(C=O)cc1Br>>CN(C)S(=O)(=O)c1ccc(CO)cc1Br -US04720500,1,Nc1ccc2ccc(Cl)nc2n1.Nc1ccccc1>>Nc1ccc2ccc(Nc3ccccc3)nc2n1 -US20120208797A1,1,CC(C)(C)OC(=O)N1CCC(CC=O)CC1.Cn1c(OC2CCNCC2)nc(-c2ccncn2)cc1=O>>Cn1c(OC2CCN(CCC3CCN(C(=O)OC(C)(C)C)CC3)CC2)nc(-c2ccncn2)cc1=O -US20150284391A1,1,COCCBr.O=c1[nH]nc(Cl)c2ccccc12>>COCCn1nc(Cl)c2ccccc2c1=O -US06528543B1,6,CCOC(=O)CNC(=O)NC(=O)C(CC1CCCC1)c1ccc(Cl)c(Cl)c1>>O=C(O)CNC(=O)NC(=O)C(CC1CCCC1)c1ccc(Cl)c(Cl)c1 -US08598154B2,2,O=C(Cl)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2.OCC1CC(OC2CCCCO2)C1>>O=C(OCC1CC(OC2CCCCO2)C1)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2 -US20050085487A1,6,CCOC(=O)c1cc2c(Cl)c(Cl)ccc2[nH]1>>O=C(O)c1cc2c(Cl)c(Cl)ccc2[nH]1 -US07273877B2,6,CCOC(=O)c1cn(CCCC#N)c(=O)cc1Nc1ccc(I)cc1F>>N#CCCCn1cc(C(=O)O)c(Nc2ccc(I)cc2F)cc1=O -US09139559B2,2,CCOC(=O)COc1nc(C(C)C)c(N)c(C(C)C)n1.CNC1CCN(Cc2ccccc2)CC1>>CC(C)c1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C(C)C)c1N -US20150141427A1,2,Nc1ccc(OC(F)(F)F)cc1.O=C(O)c1cccc(I)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(I)c1 -US20090312338A1,6,O=C(OCc1ccccc1)N1CCC(c2nnc3cnc4[nH]ccc4n23)CC1>>c1cc2c(ncc3nnc(C4CCNCC4)n32)[nH]1 -US20100222299A1,3,C=O.COc1ccc(CC(C)NC(C)=O)cc1OCc1ccccc1>>COc1cc2c(cc1OCc1ccccc1)CC(C)N(C(C)=O)C2 -US08278442B2,1,N#Cc1ccc(F)c(Cl)c1.O=Cc1ccc(O)c2ccccc12>>N#Cc1ccc(Oc2ccc(C=O)c3ccccc23)c(Cl)c1 -US20150218150A1,2,CN1Cc2cc(-c3ccc(-c4cncc(N)c4)s3)ccc2C1=O.O=S(=O)(Cl)c1cccs1>>CN1Cc2cc(-c3ccc(-c4cncc(NS(=O)(=O)c5cccs5)c4)s3)ccc2C1=O -US20140187548A1,1,CC(C)(O)CN.O=C(NC1CC1)c1ccc(-c2cnc3c(Br)nc(Br)cn23)cc1>>CC(C)(O)CNc1nc(Br)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 -US06177450B1,2,COc1ccccc1[C@H](C)C(=O)O.COc1ccccc1[C@]1(O)CCC(c2ccccc2)(c2ccccc2)[C@H]2CNC[C@H]21>>COc1ccccc1[C@H](C)C(=O)N1C[C@H]2[C@@H](C1)[C@](O)(c1ccccc1OC)CCC2(c1ccccc1)c1ccccc1 -US20100311748A1,1,C1COCCN1.Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(OCc2cc(Cl)ccn2)cc1>>Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(OCc2cc(N3CCOCC3)ccn2)cc1 -US20110212956A1,2,CC1NCCc2cccc(-c3ccco3)c21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2c(cccc2-c2ccco2)CCN1C(=O)c1cc2ncc(Br)cn2n1 -US06849622B2,1,N[C@H]1CC[C@H](N)CC1.O=[N+]([O-])c1ccc(Cl)nc1>>N[C@@H]1CC[C@@H](Nc2ccc([N+](=O)[O-])cn2)CC1 -US07750014B2,7,COC(=O)Cc1c(Cl)nc(Cc2ccc([N+](=O)[O-])cc2)n2ccnc12>>COC(=O)Cc1c(Cl)nc(Cc2ccc(N)cc2)n2ccnc12 -US20150197509A1,7,N#Cc1cc(-c2ccc(C(F)(F)F)nc2)ncn1>>NCc1cc(-c2ccc(C(F)(F)F)nc2)ncn1 -US05698697,2,CC(C)(C)O.N#CC1CNCCN1>>CC(C)(C)NC(=O)C1CNCCN1 -US05972988,1,CC(C)Br.Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1cccc(-c2ccccc2)c1>>Cc1c(C(=O)C(N)=O)c2c(OCC(=O)OC(C)C)cccc2n1Cc1cccc(-c2ccccc2)c1 -US20090005370A1,2,C1CSCCN1.COC(=O)c1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C(F)(F)F)c2)cc1>>O=C(c1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C(F)(F)F)c2)cc1)N1CCSCC1 -US20090264482A1,1,N#CCBr.N#Cc1ccc2[nH]c(C3CC3)cc2c1C(F)(F)F>>N#CCn1c(C2CC2)cc2c(C(F)(F)F)c(C#N)ccc21 -US07163937B2,2,COC(=O)[C@@H]1C[C@H](NC(C)(C)C)CC[C@@H]1N1CC[C@H](N)C1=O.O=C(O)c1cccc(C(F)(F)F)c1>>COC(=O)[C@@H]1C[C@H](NC(C)(C)C)CC[C@@H]1N1CC[C@H](NC(=O)c2cccc(C(F)(F)F)c2)C1=O -US20140336190A1,4,Cc1noc(C)c1-c1cc(N)c(N)c(I)c1.O=C(O)C1CCO1>>Cc1noc(C)c1-c1cc(I)c2nc(C3CCO3)[nH]c2c1 -US20050065178A1,2,CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1CO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1COS(C)(=O)=O -US20150072969A1,6,CCOC(=O)CC1(c2ccc(OCc3cccc(F)c3)cc2)COC1>>O=C(O)CC1(c2ccc(OCc3cccc(F)c3)cc2)COC1 -US04499000,5,O=C1CCCCC1C1CCCCC1.OCCO>>C1CCC(C2CCCCC23OCCO3)CC1 -US07148352B2,7,O=C(O)c1ccc(N2C(=O)c3ccc([N+](=O)[O-])cc3C2=O)cc1>>Nc1ccc2c(c1)C(=O)N(c1ccc(C(=O)O)cc1)C2=O -US07560558B2,6,COc1cc2ccncc2cc1Br>>Oc1cc2ccncc2cc1Br -US07834030B2,7,CCCC/C(=C\c1ccc(C#N)c(F)c1)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C>>CCCCC(Cc1ccc(C#N)c(F)c1)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C -US20140114067A1,2,CC(C)(C)c1cc(N)cc(C(C)(C)C)c1.O=C(O)Cn1c(Cc2ccc(Cl)c(Cl)c2)nc2ccccc21>>CC(C)(C)c1cc(NC(=O)Cn2c(Cc3ccc(Cl)c(Cl)c3)nc3ccccc32)cc(C(C)(C)C)c1 -US20040133011A1,6,CCCCCC12CCC(c3nnc(-c4ccc(OC)cc4C)n3C)(CC1)CC2>>CCCCCC12CCC(c3nnc(-c4ccc(O)cc4C)n3C)(CC1)CC2 -US06713645B1,1,COC(=O)c1cccc2[nH]c3c(c12)C(=O)CCC3.ClCc1cccnc1>>COC(=O)c1cccc2c1c1c(n2Cc2cccnc2)CCCC1=O -US20040014968A1,2,CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1[N+](=O)[O-].Nc1cnccn1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2cnccn2)cc1[N+](=O)[O-] -US20030139400A1,1,CI.COc1cc2ncc(O[C@@H]3CC[C@@H](O)CC3)nc2cc1OC>>COc1cc2ncc(OC3CCC(OC)CC3)nc2cc1OC -US08217051B2,3,O=C1Cc2cc(F)c(Cl)cc2N1.O=Cc1cccc(Cl)c1>>O=C1Nc2cc(Cl)c(F)cc2/C1=C/c1cccc(Cl)c1 -US20140142074A1,2,C1COCCN1.O=C(CNS(=O)(=O)c1ccc(C(=O)O)cc1)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1>>O=C(CNS(=O)(=O)c1ccc(C(=O)N2CCOCC2)cc1)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 -US06153768,1,COCOc1ccc(C2COc3cc(OCOC)ccc3C2(O)c2ccc(O)cc2)cc1.ClCCCCCBr>>COCOc1ccc(C2COc3cc(OCOC)ccc3C2(O)c2ccc(OCCCCCCl)cc2)cc1 -US20110059957A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cncc(N2CCNCC2)c1>>CC(C)(C)OC(=O)N1CCN(c2cccnc2)CC1 -US04233309,3,CC(=O)OCCn1c(C)ccc1C.O=C(Cl)c1ccc(Cl)cc1>>CC(=O)OCCn1c(C)cc(C(=O)c2ccc(Cl)cc2)c1C -US08114989B2,6,C[C@H](NC(=O)OC(C)(C)C)c1ccc(Br)cn1>>C[C@H](N)c1ccc(Br)cn1 -US20150087639A1,1,C1COCCN1.N#CCCCBr>>N#CCCCN1CCOCC1 -US08623866B2,1,CCOC(=O)c1nc(NCCOC)ncc1Br.Nc1cncnc1>>CCOC(=O)c1nc(NCCOC)ncc1Nc1cncnc1 -US08273794B2,2,CC(C)Nc1ccccc1.CCOC(=O)CCCCCC(=O)O>>CC(C)N(C(=O)CCCCCC(=O)O)c1ccccc1 -US20150119385A1,3,COCCNc1cc(NC(=O)N2CCCc3cc(Br)c(C(OC)OC)nc32)ncc1C#N.Cn1nccc1B(O)O>>COCCNc1cc(NC(=O)N2CCCc3cc(-c4ccnn4C)c(C(OC)OC)nc32)ncc1C#N -US07910740B2,1,COc1cc(Nc2nc([C@@H](N)CC(C)C)cs2)ccc1-n1cnc(C)c1.O=Cc1ccc(F)cc1>>COc1cc(Nc2nc([C@H](CC(C)C)NCc3ccc(F)cc3)cs2)ccc1-n1cnc(C)c1 -US08063212B2,3,CC1(C)OB(c2cccc3ccsc23)OC1(C)C.Fc1cc(I)c(CN2CCOCC2)cn1>>Fc1cc(-c2cccc3ccsc23)c(CN2CCOCC2)cn1 -US06780878B2,1,COc1ccc(NC(=O)c2cccnc2Cl)cc1.NCC1CCN(c2ccncc2)CC1>>COc1ccc(NC(=O)c2cccnc2NCC2CCN(c3ccncc3)CC2)cc1 -US04963568,7,COc1ccc2c(c1OC)CC(c1ccccc1)C=C2C#N>>COc1ccc2c(c1OC)CC(c1ccccc1)CC2C#N -US05236902,1,Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCO)[C@@H](O)[C@H]1O.O=[N+]([O-])c1ccc(CBr)cc1>>O=[N+]([O-])c1ccc(CNc2ncnc3c2ncn3[C@@H]2O[C@H](CSCCO)[C@@H](O)[C@H]2O)cc1 -US20030055244A1,6,CCOC(=O)CCN1CCC(C(=O)OCc2ccccc2)CC1>>CCOC(=O)CCN1CCC(C(=O)O)CC1 -US20050288304A1,2,C1COCCN1.COC(=O)c1ccc(C(=O)N2CCCC(c3ccc4c(c3)C(N3CCN(C)CC3)CCC4)C2)cc1>>CN1CCN(C2CCCc3ccc(C4CCCN(C(=O)c5ccc(C(=O)N6CCOCC6)cc5)C4)cc32)CC1 -US20040220178A1,2,CC(C)(C)OC(=O)N1CCc2[nH]c3c(N)cccc3c2C1.O=C(Cl)CCCl>>CC(C)(C)OC(=O)N1CCc2[nH]c3c(NC(=O)CCCl)cccc3c2C1 -US07449473B2,7,CCOC(=O)c1cnn(Cc2ccccc2)c1>>OCc1cnn(Cc2ccccc2)c1 -US20070032528A1,2,CCOC(=O)Cc1nc2ccccc2[nH]1.N#Cc1ccncc1N>>N#Cc1ccncc1NC(=O)Cc1nc2ccccc2[nH]1 -US20080096892A1,1,O=C(CCl)Nc1ccc(Cl)c(C(F)(F)F)c1.Oc1ccc(Br)cc1>>O=C(COc1ccc(Br)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 -US20100273786A1,6,COC(=O)c1nc(C(F)(F)F)n2c1[C@@H](C)N(C(=O)CC(Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)CC2>>COC(=O)c1nc(C(F)(F)F)n2c1[C@@H](C)N(C(=O)CC(N)Cc1cc(F)c(F)cc1F)CC2 -US20010023249A1,1,CC(C)(C)OC(=O)N1CCC(Nc2ccc(OCc3ccccc3)cc2)CC1.CC(C)CC=O>>CC(C)CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)OC(C)(C)C)CC1 -US20120129811A1,2,COc1ccc(S(C)(=O)=O)cc1N=C=S.Nc1cccc2[nH]ncc12>>COc1ccc(S(C)(=O)=O)cc1NC(=S)Nc1cccc2[nH]ncc12 -US20090029981A1,2,C1COCCN1.COCCCOc1ccc([C@H]2[C@H](OCC(=O)O)CN(C(=O)OCc3ccccc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1>>COCCCOc1ccc([C@H]2[C@H](OCC(=O)N3CCOCC3)CN(C(=O)OCc3ccccc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1 -US20100029707A1,8,OC1CCc2cnc3c(c21)CCO3>>O=C1CCc2cnc3c(c21)CCO3 -US07557213B2,6,O=C(c1ccc(C2OCCCO2)cc1)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O>>O=Cc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1 -US08513421B2,1,COc1ccc(CN)cc1.O=[N+]([O-])c1cc[n+]([O-])c(Cl)c1>>COc1ccc(CNc2cc([N+](=O)[O-])cc[n+]2[O-])cc1 -US08071773B2,2,CC(C)(C)OC(=O)N1CCCC2(CCN(Cc3ccccc3)C2)C1CO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCCC2(CCN(Cc3ccccc3)C2)C1COS(C)(=O)=O -US04215123,2,CCOC(=O)c1c(O)c2ccc(C)nc2n(CC)c1=O.COCCN>>CCn1c(=O)c(C(=O)NCCOC)c(O)c2ccc(C)nc21 -US07008940B1,1,C=C(C)CCl.Cc1c(O)cc2c(c1C)N(C=O)CC2>>C=C(C)COc1cc2c(c(C)c1C)N(C=O)CC2 -US20130281392A1,4,Nc1cc(Cl)c(-c2ccc(C(F)(F)F)cc2C(F)(F)F)cc1N.O=C(O)C(F)(F)C(F)(F)F>>FC(F)(F)c1ccc(-c2cc3[nH]c(C(F)(F)C(F)(F)F)nc3cc2Cl)c(C(F)(F)F)c1 -US20150087585A1,1,CCN(C)C(=O)[C@@H]1CCCNC1.Nc1nc(Cl)ccc1[N+](=O)[O-]>>CCN(C)C(=O)[C@@H]1CCCN(c2ccc([N+](=O)[O-])c(N)n2)C1 -US20090197866A1,6,CCN(CC)C(=O)Nc1cn(C2CCCCO2)nc1-c1nc2cc(F)c(N3CCN(C)CC3)cc2[nH]1>>CCN(CC)C(=O)Nc1c[nH]nc1-c1nc2cc(F)c(N3CCN(C)CC3)cc2[nH]1 -US20130035292A1,6,NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)OCc1ccccc1>>NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CO -US20110207701A1,10,Cc1cccc([N+](=O)[O-])c1Br.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1cccc(CBr)c1Br -US04028344,2,CC(C)CC(C)(N=C=S)N=NC(C)(C)C.CCCCN>>CCCCNC(=S)NC(C)(CC(C)C)N=NC(C)(C)C -US07528256B2,9,O=C(O)c1cncc(Br)c1>>O=Cc1cncc(Br)c1 -US20100280030A1,3,Brc1cnc(I)nc1.OCc1cccc(B(O)O)c1>>OCc1cccc(-c2ncc(Br)cn2)c1 -US07763617B2,3,CC[Mg+].COc1ccc(C=O)c2cc(C(F)(F)F)nn12>>CCC(O)c1ccc(OC)n2nc(C(F)(F)F)cc12 -US20080194625A1,6,O=C(NC1Cc2cc(C(F)(F)F)ccc2N(Cc2ccccc2)C1)OCc1ccccc1>>NC1Cc2cc(C(F)(F)F)ccc2N(Cc2ccccc2)C1 -US20140288123A1,2,CNc1cc(C)nc(O)c1CN.O=C(O)c1ccc(Oc2ccccc2)cc1>>CNc1cc(C)nc(O)c1CNC(=O)c1ccc(Oc2ccccc2)cc1 -US20060111355A1,1,ClCCCl.NC(=O)c1cccc(O)c1>>NC(=O)c1cccc(OCCCl)c1 -US20060287343A1,2,CO.O=C(O)Cc1ccc(F)cc1I>>COC(=O)Cc1ccc(F)cc1I -US07211586B2,6,CCOC(=O)CC(C)c1ccc2c(c1)CCNC2C(=O)Cc1cc(C)c2nc(Nc3ccccc3C)oc2c1>>Cc1ccccc1Nc1nc2c(C)cc(CC(=O)C3NCCc4cc(C(C)CC(=O)O)ccc43)cc2o1 -US08524751B2,2,C[C@H]1CN(CC(=O)NN)C[C@@H](C)O1.Cc1ccc(S(=O)(=O)n2ncc3c(C(=O)O)cc(Br)cc32)cc1>>Cc1ccc(S(=O)(=O)n2ncc3c(C(=O)NNC(=O)CN4C[C@H](C)O[C@H](C)C4)cc(Br)cc32)cc1 -US20100286112A1,1,CC(C)c1noc(N2CCC([C@H](C)CCO)CC2)n1.COC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)c1ccc(O)cc1F>>COC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)c1ccc(OCC[C@@H](C)C2CCN(c3nc(C(C)C)no3)CC2)cc1F -US08329682B2,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN(C)C)CCC2.O=C1Cc2c(cccc2-c2cccc(F)c2F)N1>>Cc1c(/C=C2\C(=O)Nc3cccc(-c4cccc(F)c4F)c32)[nH]c2c1C(=O)N(CCN(C)C)CCC2 -US20110201640A1,1,CC(O)c1ccc2c(c1)CCc1ccccc1/C2=C\C#N.CCc1nc2c(C)cc(C)nc2[nH]1>>CCc1nc2c(C)cc(C)nc2n1C(C)c1ccc2c(c1)CCc1ccccc1/C2=C\C#N -US08173813B2,7,O=C1CCc2cc([N+](=O)[O-])ccc2N1CCN1CCOCC1>>Nc1ccc2c(c1)CCC(=O)N2CCN1CCOCC1 -US08962627B2,1,CC(C)(C)ON=c1cc(-c2cc3sccc3cn2)oc2ccc(O)cc12.ClCCN1CCOCC1>>CC(C)(C)ON=c1cc(-c2cc3sccc3cn2)oc2ccc(OCCN3CCOCC3)cc12 -US20110263673A1,6,COC(=O)c1c[nH]c(-c2ccc(F)cc2Cl)c1C>>Cc1c(C(=O)O)c[nH]c1-c1ccc(F)cc1Cl -US20150175563A1,6,COC(=O)c1sc(N2CCOCC2)c(C#N)c1Cc1ccc2ccncc2c1>>N#Cc1c(N2CCOCC2)sc(C(=O)O)c1Cc1ccc2ccncc2c1 -US09073929B2,3,Brc1ccc2c(c1)CCc1nncn1-2.C=CC1(c2cncc(B(O)O)c2)CC1>>C=CC1(c2cncc(-c3ccc4c(c3)CCc3nncn3-4)c2)CC1 -US20100144722A1,6,COC(=O)C1(c2ccc(Nc3nc(-c4c(C)noc4C)cc(N4CCOCC4)n3)cc2)CCC1>>Cc1noc(C)c1-c1cc(N2CCOCC2)nc(Nc2ccc(C3(C(=O)O)CCC3)cc2)n1 -US05880135,4,CCCN(C(N)=S)c1cccc2ccccc12.COc1ccc(C(=O)C(C)Br)c(Cl)c1>>CCCN(c1nc(-c2ccc(OC)cc2Cl)c(C)s1)c1cccc2ccccc12 -US20100267712A1,10,CCOC(=O)c1cc(OC(F)(F)C(F)Cl)ccc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1cc(OC(F)(F)C(F)Cl)ccc1CBr -US20050113379A1,1,CCI.CCc1nc(O)c(Br)cc1S(C)(=O)=O>>CCOc1nc(CC)c(S(C)(=O)=O)cc1Br -US20150025087A1,2,COc1cccc(F)c1Cn1cc(C(=O)O)c2ncccc21.NCC1CC1>>COc1cccc(F)c1Cn1cc(C(=O)NCC2CC2)c2ncccc21 -US05061808,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)CC1NC(=O)CC1OC1CCCCO1>>CC(C)C[C@H]1[C@@H](OC2CCCCO2)CC(=O)N1C(=O)OC(C)(C)C -US20130172339A1,2,Nc1cccc(-c2nnn[nH]2)c1.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1Cl>>O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(Cl)c(Cl)c1Cl -US20150148327A1,3,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(B2OC(C)(C)C(C)(C)O2)c1.O=C(O)c1ccc(Br)cn1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(C(=O)O)nc2)c1 -US07560569B2,2,N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2.N#Cc1ccc(N)cc1>>N#Cc1ccc(NC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)cc1 -US08735388B2,3,C#CCCCC.O=S(=O)(c1ccccc1)n1cc(I)c(-c2cccnc2)n1>>CCCCC#Cc1cn(S(=O)(=O)c2ccccc2)nc1-c1cccnc1 -US20150175601A1,10,Cc1ccc2cnc(Cl)nc2c1Br.O=C1CCC(=O)N1Br>>Clc1ncc2ccc(CBr)c(Br)c2n1 -USRE037478E1,1,CNc1cc(C(C)=O)ccc1OCCCCl.Fc1ccc2c(C3CCNCC3)noc2c1>>CNc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1 -US20100292279A1,3,C#Cc1cccc(F)c1.COc1cc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)ccc1Br>>COc1cc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)ccc1C#Cc1cccc(F)c1 -US20120232096A1,1,COc1ccc(N2CCNCC2)cc1.Cc1cc(Br)c(C)c2c1OC(C)(C)C2>>COc1ccc(N2CCN(c3cc(C)c4c(c3C)CC(C)(C)O4)CC2)cc1 -US20070088018A1,2,NCc1ccc(F)cc1.O=C(O)c1ccc(S(=O)(=O)n2cc(-c3ccccc3)c3ccccc32)cc1>>O=C(NCc1ccc(F)cc1)c1ccc(S(=O)(=O)n2cc(-c3ccccc3)c3ccccc32)cc1 -US20070232702A1,2,CCCCN.CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12>>CCCCNS(=O)(=O)c1cccc2c(N(C)C)cccc12 -US20090181946A1,7,O=C1[C@H](NC(c2ccccc2)(c2ccccc2)c2ccccc2)CCc2ccccc2N1CC(F)(F)F>>FC(F)(F)CN1C[C@H](NC(c2ccccc2)(c2ccccc2)c2ccccc2)CCc2ccccc21 -US20030191160A1,1,CC(=O)Nc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F.CI>>CC(=O)N(C)c1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F -US04055574,7,COc1cccc(C(=O)O)c1>>COc1cccc(CO)c1 -US20060270706A1,8,CC(C)(C)[Si](C)(C)OC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C/C1=C\CO>>CC(C)(C)[Si](C)(C)OC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C/C1=C\C=O -US20080194647A1,3,C#Cc1cncc(Br)c1.Fc1ccc(I)cc1>>Fc1ccc(C#Cc2cncc(Br)c2)cc1 -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.[Mg+]C1CCCCC1>>COc1ccc2c(C3CCCCC3)nc(Nc3cc(C)[nH]n3)cc2c1 -US04377576,2,C=CC(=O)O.O=C1Nc2ccccc2Nc2ccccc21>>C=CC(=O)N1c2ccccc2NC(=O)c2ccccc21 -US20100029623A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1cc(F)ccc1F>>CCOC(=O)/C=C/c1cc(F)ccc1F -US20140128401A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)ccnc1-n1ncc2cc(C(C)(C)C)cc(F)c2c1=O.Cn1cc(Nc2cc(Br)cn(C)c2=O)nn1>>CC(=O)OCc1c(-c2cc(Nc3cn(C)nn3)c(=O)n(C)c2)ccnc1-n1ncc2cc(C(C)(C)C)cc(F)c2c1=O -US20080255085A1,2,CN1CCNCC1.COc1ccc(-c2ccnc3[nH]c(-c4cncc(C(=O)O)c4)nc23)cc1>>COc1ccc(-c2ccnc3[nH]c(-c4cncc(C(=O)N5CCN(C)CC5)c4)nc23)cc1 -US20150225422A1,2,Nc1cncc(Br)c1.O=S(=O)(Cl)CCCCl>>O=S(=O)(CCCCl)Nc1cncc(Br)c1 -US20110086854A1,6,COC(=O)C1CCC(CNC(=O)N2C[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)CC1>>CC(C)(C)C[C@@H]1CN(C(=O)NCC2CCC(C(=O)O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20110312937A1,1,COc1ccc(C(NC2=N[C@](C)(c3cc(Br)ccc3F)C(F)(F)COC2)(c2ccccc2)c2ccc(OC)cc2)cc1.N=C(c1ccccc1)c1ccccc1>>COc1ccc(C(NC2=N[C@](C)(c3cc(N=C(c4ccccc4)c4ccccc4)ccc3F)C(F)(F)COC2)(c2ccccc2)c2ccc(OC)cc2)cc1 -US20090099195A1,1,CN.ClCc1cc2ccc(Cl)cc2cn1>>CNCc1cc2ccc(Cl)cc2cn1 -US04361439,2,CCOC(=O)[C@H](C)N.O=C(Cl)CCl>>CCOC(=O)[C@H](C)NC(=O)CCl -US20030100789A1,9,Fc1ccc(CBr)cc1Oc1ccccc1.[C-]#N>>N#CCc1ccc(F)c(Oc2ccccc2)c1 -US07504416B2,1,COc1ccnc(Cl)c1.Nc1ccc(O)cc1>>COc1ccnc(Oc2ccc(N)cc2)c1 -US06265426B1,2,COC(=O)c1ccc(OCF)cc1.NN>>NNC(=O)c1ccc(OCF)cc1 -US20080194549A1,1,CN.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C=O)C(C)C)ccc1OC>>CNC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C -US05604229,6,CC(=O)NC(CO)(CO)CCCc1ccc([N+](=O)[O-])cc1>>NC(CO)(CO)CCCc1ccc([N+](=O)[O-])cc1 -US08039450B2,1,CCOC(=O)c1ccc(F)cc1OC.Oc1ccc(Br)c(C2OCCO2)c1>>CCOC(=O)c1ccc(Oc2ccc(Br)c(C3OCCO3)c2)cc1OC -US20030082623A1,1,C[C@H]1CNCCN1.O=[N+]([O-])c1ccccc1Br>>C[C@H]1CN(c2ccccc2[N+](=O)[O-])CCN1 -US20120149721A1,2,COCC(=O)Cl.Cc1[nH]c2c(-c3cc(C(F)F)ccc3OCC3CC3)ncnc2c1C(=O)N[C@H]1CC[C@H](N)[C@@H](C)C1>>COCC(=O)N[C@H]1CC[C@H](NC(=O)c2c(C)[nH]c3c(-c4cc(C(F)F)ccc4OCC4CC4)ncnc23)C[C@@H]1C -US07632857B2,2,CS(=O)(=O)c1ccc(-c2ccc(C(=O)O)cc2)cc1.C[C@@H]1CCCN1C[C@@H]1CCCN1>>C[C@@H]1CCCN1C[C@@H]1CCCN1C(=O)c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1 -US20090203674A1,1,CC#CCOc1cc(Cl)ncn1.CC1(C)CCNC1>>CC#CCOc1cc(N2CCC(C)(C)C2)ncn1 -US06384041B1,6,CCc1c(C(=O)C(N)=O)c2c(OCC(=O)OC)nc(SC)nc2n1Cc1ccccc1>>CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)nc(SC)nc2n1Cc1ccccc1 -US08058045B2,1,C1COCCN1.CC(C)(C)OC(=O)N1CCCC(CNc2cc(Nc3cnc(C#N)cn3)ncc2-n2ccc(C=O)c2)C1>>CC(C)(C)OC(=O)N1CCCC(CNc2cc(Nc3cnc(C#N)cn3)ncc2-n2ccc(CN3CCOCC3)c2)C1 -US20060205812A1,3,COCOc1cc(OS(=O)(=O)C(F)(F)F)ccc1CCNS(=O)(=O)c1cc(C#N)ccc1OC.CSc1ccccc1B(O)O>>COCOc1cc(-c2ccccc2SC)ccc1CCNS(=O)(=O)c1cc(C#N)ccc1OC -US07101886B2,2,CC(=O)OC(C)=O.Cc1ccc(Cl)cc1N>>CC(=O)Nc1cc(Cl)ccc1C -US20150152108A1,1,CI.O=C(Nc1ccccn1)N1c2nc(-c3cccc(C(F)(F)F)c3)ccc2N2CC[C@H]1C2>>CN(C(=O)N1c2nc(-c3cccc(C(F)(F)F)c3)ccc2N2CC[C@H]1C2)c1ccccn1 -US20150056305A1,6,COC(=O)[C@H](CCCCNC(=O)[C@H](CCCCNC(=O)[C@H](CCCCNC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N=C(NCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)NC(=O)OC(C)(C)C -US05563142,6,COC(=O)c1cc2cc(Br)c(OC)cc2[nH]1>>COc1cc2[nH]c(C(=O)O)cc2cc1Br -US20110086860A1,6,COc1cc(/C=C(\CCCCl)C(=O)OC(C)(C)C)ccc1-n1cnc(C)c1>>COc1cc(/C=C(\CCCCl)C(=O)O)ccc1-n1cnc(C)c1 -US20050020593A1,2,Clc1cccc(N2CCNCC2)c1.O=C(O)c1c(-c2ccccc2)sc2ccccc12>>O=C(c1c(-c2ccccc2)sc2ccccc12)N1CCN(c2cccc(Cl)c2)CC1 -US07326791B2,2,CC(N)c1nc2cc(Cl)ccc2[nH]1.O=C(O)c1ccc(C(=O)N2CCCC2)cc1>>CC(NC(=O)c1ccc(C(=O)N2CCCC2)cc1)c1nc2cc(Cl)ccc2[nH]1 -US07935699B2,7,CCS(=O)(=O)n1ccc([N+](=O)[O-])n1>>CCS(=O)(=O)n1ccc(N)n1 -US20090286985A1,3,Brc1cccnc1.OB(O)c1c2ccccc2cc2ccccc12>>c1cncc(-c2c3ccccc3cc3ccccc23)c1 -US20090048286A1,1,CC(C)(C)OC(=O)CBr.COC(=O)c1sc2ncc(Br)cc2c1O>>COC(=O)c1sc2ncc(Br)cc2c1OCC(=O)OC(C)(C)C -US20140155418A1,1,COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O.ClCC1CN2CSC[C@H]2CO1>>COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN2CSC[C@H]2CO1 -US06936602B1,6,COC(=O)C1=Cc2cc(-c3ccc(N4CCOCC4)cc3)ccc2N(S(C)(=O)=O)CC1>>CS(=O)(=O)N1CCC(C(=O)O)=Cc2cc(-c3ccc(N4CCOCC4)cc3)ccc21 -US04168267,1,C=[N+]=[N-].CP(=O)(CC(=O)O)OCc1ccccc1>>COC(=O)CP(C)(=O)OCc1ccccc1 -US20060211695A1,7,Cc1c(OCCN(C)C)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12>>Cc1c(OCCN(C)C)cn2ncnc(Oc3ccc(N)cc3F)c12 -US20080207708A1,1,CC(C)CI.CCOC(=O)c1csc(Cc2cc(Cl)ccc2O)n1>>CCOC(=O)c1csc(Cc2cc(Cl)ccc2OCC(C)C)n1 -US06627771B1,6,COC(=O)C(CC(=O)OC(C)(C)C)C1CCCC1>>CC(C)(C)OC(=O)CC(C(=O)O)C1CCCC1 -US05362738,6,O=C(OCc1ccccc1)c1cc(-c2ccccc2)c(=O)n2c1-c1ccccc1C2>>O=C(O)c1cc(-c2ccccc2)c(=O)n2c1-c1ccccc1C2 -US08492437B2,1,CC(C(=O)OC(C)(C)C)c1ccc(F)c(C#N)c1.O=C(Nc1ccc(O)cc1)c1ccc(Cl)c(Cl)c1>>CC(C(=O)OC(C)(C)C)c1ccc(Oc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C#N)c1 -US20120129811A1,2,COc1ccc(S(C)(=O)=O)cc1N=C=S.Cn1cnc2cccc(N)c21>>COc1ccc(S(C)(=O)=O)cc1NC(=S)Nc1cccc2ncn(C)c12 -US20130053409A1,1,CNCCN1CCOCC1.COc1cc(F)c([N+](=O)[O-])cc1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1>>COc1cc(N(C)CCN2CCOCC2)c([N+](=O)[O-])cc1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1 -US20120208819A1,1,Fc1ccc(CBr)cc1F.O=C1NCCc2ccnc(Cl)c21>>O=C1c2c(ccnc2Cl)CCN1Cc1ccc(F)c(F)c1 -US08759336B2,2,CC(=O)OC(C)=O.Nc1ccccc1F>>CC(=O)Nc1ccccc1F -US09090632B2,9,CC(C)(C)OC(=O)N1CCC(O)C(N=[N+]=[N-])C1>>CC(C)(C)OC(=O)N1CCC(O)C(N)C1 -US20090099205A1,1,CC(C)(C)OC(=O)N[C@@H](CN)c1ccccc1.CC(C)C=O>>CC(C)CNC[C@H](NC(=O)OC(C)(C)C)c1ccccc1 -US20130338173A1,1,CC(C)=O.CC1(C)O[C@@H]2[C@H](O1)[C@@H](CN)C[C@H]2n1ccc2c(NC3CC3)ncnc21>>CC(C)NC[C@H]1C[C@@H](n2ccc3c(NC4CC4)ncnc32)[C@@H]2OC(C)(C)O[C@H]12 -US08835470B2,2,NCc1ncn[nH]1.O=C(O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1>>O=C(NCc1ncn[nH]1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 -US20150111894A1,3,COc1cc(-n2ccc3oc(Br)cc3c2=O)ccc1OCC1(C#N)CC1.OB(O)c1ccc(C(F)(F)F)cc1>>COc1cc(-n2ccc3oc(-c4ccc(C(F)(F)F)cc4)cc3c2=O)ccc1OCC1(C#N)CC1 -US20100143341A1,1,CCC(C)Oc1ccccc1N.CCc1csc2ncnc(Cl)c12>>CCc1csc2ncnc(Nc3ccccc3OC(C)CC)c12 -US20130131068A1,2,FC(F)(F)c1nc2n(n1)CCNC2.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCn2nc(C(F)(F)F)nc2C1 -US05561141,6,COc1ccc(C(C#N)(CCCCCN2C(=O)c3ccccc3C2=O)Sc2ccc(C)cc2)cc1OC>>COc1ccc(C(C#N)(CCCCCN)Sc2ccc(C)cc2)cc1OC -US06225306B1,2,O=C(O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1.c1ccc2c(c1)NC[C@H]1CCCN21>>O=C(Nc1ccc(C(=O)N2C[C@H]3CCCN3c3ccccc32)cc1)c1ccccc1-c1ccccc1 -US08722662B2,6,COCC(=O)NC[C@@H]1CN(C(=O)OC(C)(C)C)CCO[C@H]1c1ccc(Cl)c(Cl)c1>>COCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 -US20140328805A1,6,CC(C)(C)OC(=O)N1CCC(c2cc(Cl)nc(Cl)c2)CC1>>Clc1cc(C2CCNCC2)cc(Cl)n1 -US07605161B2,7,O=C(c1ccccc1C(F)(F)F)N1CCN(c2ccc([N+](=O)[O-])cn2)CC1>>Nc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nc1 -US20090093491A1,1,Clc1ncc(CCCCn2cccn2)cn1.OCc1coc(C=Cc2ccc(OC(F)(F)F)cc2)n1>>FC(F)(F)Oc1ccc(/C=C/c2nc(COc3ncc(CCCCn4cccn4)cn3)co2)cc1 -US20050250795A1,6,CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COS(=O)(=O)c1ccccc1C)CC(OCC)OCC>>CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CC=O)COS(=O)(=O)c1ccccc1C -US20060264460A1,7,CSc1cc([N+](=O)[O-])cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc12>>CSc1cc(N)cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc12 -US20080167314A1,2,Cc1cccc(-c2nc3cccnn3c2-c2ccnc(N)c2)c1.O=C(Cl)C1CC1>>Cc1cccc(-c2nc3cccnn3c2-c2ccnc(NC(=O)C3CC3)c2)c1 -US20070037846A1,1,CCCCBr.Cc1cc(C=O)ccc1O>>CCCCOc1ccc(C=O)cc1C -US20140228405A1,1,N[C@@H]1C[C@H]1c1ccc(NC(=O)[C@@H](Cc2ccccc2)NC(=O)OCc2ccccc2)cc1.O=Cc1ccccc1>>O=C(N[C@H](Cc1ccccc1)C(=O)Nc1ccc([C@@H]2C[C@H]2NCc2ccccc2)cc1)OCc1ccccc1 -US20100210619A1,2,Cc1cc(O)c(C)cc1N.O=C(O)c1cc(NC2CCCCC2)ncn1>>Cc1cc(NC(=O)c2cc(NC3CCCCC3)ncn2)c(C)cc1O -US20110257205A1,2,NNC(=O)Cc1ccc(F)cc1Cl.O=C(Cl)CCCCl>>O=C(CCCCl)NNC(=O)Cc1ccc(F)cc1Cl -US20110071194A1,1,CC(=O)C(Oc1cc2cnn(-c3ccc(F)cc3)c2cc1Cl)c1ccc(F)cc1.[NH4+]>>CC(N)C(Oc1cc2cnn(-c3ccc(F)cc3)c2cc1Cl)c1ccc(F)cc1 -US20050228004A1,6,COc1cccc(-c2nc3c(NC4CCCC4)cccn3c2-c2ccnc(NC3CCCC3)n2)c1>>Oc1cccc(-c2nc3c(NC4CCCC4)cccn3c2-c2ccnc(NC3CCCC3)n2)c1 -US20140114068A1,7,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NC(=O)/C=C/c1ccc(Cl)c(Cl)c1>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NC(=O)/C=C/c1ccc(Cl)c(Cl)c1 -US06660752B2,2,CC(C)(C)OC(=O)N(C[C@@H]1CCc2cc(-c3cccc(S(N)(=O)=O)c3)ccc2O1)C[C@H](O[Si](C)(C)C(C)(C)C)c1cccnc1.COCC(=O)O>>COCC(=O)NS(=O)(=O)c1cccc(-c2ccc3c(c2)CC[C@@H](CN(C[C@H](O[Si](C)(C)C(C)(C)C)c2cccnc2)C(=O)OC(C)(C)C)O3)c1 -US20150080372A1,2,CN=C=O.O=C(c1c(F)ccc(NS(=O)(=O)c2cc(F)ccc2F)c1F)c1c[nH]c2ncc(-c3ccc4[nH]ncc4c3)cc12>>CNC(=O)n1ncc2cc(-c3cnc4[nH]cc(C(=O)c5c(F)ccc(NS(=O)(=O)c6cc(F)ccc6F)c5F)c4c3)ccc21 -US20060247251A1,2,N#Cc1ncc2cc(COc3ccc(N)cc3)n(CCC3CCCCC3)c2n1.O=S(=O)(Cl)CC(F)(F)F>>N#Cc1ncc2cc(COc3ccc(NS(=O)(=O)CC(F)(F)F)cc3)n(CCC3CCCCC3)c2n1 -US05569664,1,C#CCOc1ccc(CCl)cc1.OC(c1ccc(OC(F)(F)F)cc1)(c1ccc(OC(F)(F)F)cc1)C1CCNCC1>>C#CCOc1ccc(CN2CCC(C(O)(c3ccc(OC(F)(F)F)cc3)c3ccc(OC(F)(F)F)cc3)CC2)cc1 -US20070021473A1,1,CCOC(=O)c1ccc(-c2ccc(OCCCI)c(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c2)cc1.CN>>CCOC(=O)c1ccc(-c2ccc(OCCCNC)c(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c2)cc1 -US04774266,1,CCCCCCBr.c1ccc(-c2nnn[nH]2)cc1>>CCCCCCn1nnnc1-c1ccccc1 -US04880817,1,CCI.COC(=O)c1c(O)nc(C)c2cc(OC)c(OC)cc12>>CCOc1nc(C)c2cc(OC)c(OC)cc2c1C(=O)OC -US09079880B2,6,COC(=O)c1cccc(O[C@@H]2CCN(c3ccc(C#N)cc3)C2=O)c1>>N#Cc1ccc(N2CC[C@@H](Oc3cccc(C(=O)O)c3)C2=O)cc1 -US08202513B2,1,CC(CCBr)c1ccc(F)cc1.COc1cc(C)cc(OC)c1O>>COc1cc(C)cc(OC)c1OCCC(C)c1ccc(F)cc1 -US20130225524A1,6,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4cc(OC)nc(C(F)(F)F)c4)ccc23)c1>>COc1cc(-c2ccc3c(Nc4cccc(C(=O)O)c4)c(C(N)=O)cnc3c2)cc(C(F)(F)F)n1 -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)NCc1cc(C(F)(F)F)ccc1F>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC(=O)NCc4cc(C(F)(F)F)ccc4F)cc3)cc2)CC1 -US20100152158A1,6,OC1(c2cccnc2)CCN(Cc2ccccc2)CC1>>OC1(c2cccnc2)CCNCC1 -US07192968B2,6,CN(Cc1ccccc1)[C@@H]1CCCC[C@@H]1NC(=O)OC(C)(C)C>>CN[C@H]1CCCC[C@H]1NC(=O)OC(C)(C)C -US07148234B2,1,Cc1nc(Cl)c([N+](=O)[O-])c(C)c1C#N.Nc1ccc(CCO)cc1>>Cc1nc(Nc2ccc(CCO)cc2)c([N+](=O)[O-])c(C)c1C#N -US04785113,9,Cc1nc(Cl)c(C)c(Cl)c1C>>Cc1cnc(C)c(C)c1Cl -US20010000513A1,9,NO.O=C(O)CCC(=O)c1ccc(-c2ccc(Br)cc2)cc1>>O=C(O)CCC(=NO)c1ccc(-c2ccc(Br)cc2)cc1 -US05321029,1,BrCC1CCCCC1.CC(=O)CCn1cnc2[nH]c(=O)n(CC3CC3)c(=O)c21>>CC(=O)CCn1cnc2c1c(=O)n(CC1CC1)c(=O)n2CC1CCCCC1 -US08299085B2,6,COC(=O)c1cc([N+](=O)[O-])c(C(F)(F)F)cc1N>>Nc1cc(C(F)(F)F)c([N+](=O)[O-])cc1C(=O)O -US07041826B2,6,CN1CCN(Cc2ccccc2)C(c2ccccc2)C1=O>>CN1CCNC(c2ccccc2)C1=O -US20040167123A1,1,NS(=O)(=O)c1cc(Br)ccc1NC(=O)c1c(O)c2cccnc2n(Cc2ccccc2)c1=O>>O=c1c(C2=NS(=O)(=O)c3cc(Br)ccc3N2)c(O)c2cccnc2n1Cc1ccccc1 -US20150239844A1,2,COC(=O)c1ccc(S(=O)(=O)Cl)s1.Oc1cc(NC2CCNCC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2n1>>COC(=O)c1ccc(S(=O)(=O)N2CCC(Nc3cc(O)nc4ccc(C(c5ccc(Cl)cc5)c5ccc(Cl)cc5)cc34)CC2)s1 -US05541198,9,Cc1cc(Br)ccc1N.S=C=S>>Cc1cc(Br)ccc1N=C=S -US06057358,1,BrCCBr.Oc1ccc(-n2ccnc2)cc1>>BrCCOc1ccc(-n2ccnc2)cc1 -US20130296322A1,9,CC(C)(C)OC(=O)N1CC[C@H]([C@@H](CN=[N+]=[N-])Oc2ccc(C(F)(F)F)cc2)C1>>CC(C)(C)OC(=O)N1CC[C@H]([C@@H](CN)Oc2ccc(C(F)(F)F)cc2)C1 -US20130109652A1,6,CC(C)(C)OC(=O)NCCOc1ccc(-c2ccc(=O)n(Cc3ccc(Cl)cc3F)c2)cc1>>NCCOc1ccc(-c2ccc(=O)n(Cc3ccc(Cl)cc3F)c2)cc1 -US20120094972A1,1,C1COCCN1.CC(C)(C)OC(=O)N1CC2(CCS(=O)(=O)CC2)c2ccc(Br)cc21>>CC(C)(C)OC(=O)N1CC2(CCS(=O)(=O)CC2)c2ccc(N3CCOCC3)cc21 -US20080234199A1,1,CCCC(=O)c1ccc(O)c(OC)c1.CCOC(=O)CCCBr>>CCCC(=O)c1ccc(OCCCC(=O)OCC)c(OC)c1 -US08088767B2,1,C=O.O=C(Nc1nc2ccccc2[nH]1)c1nc[nH]c1C(=O)Nc1ccc(OC2CCNCC2)cc1Cl>>CN1CCC(Oc2ccc(NC(=O)c3[nH]cnc3C(=O)Nc3nc4ccccc4[nH]3)c(Cl)c2)CC1 -US04399148,2,CN(SSC(C)(C)C)C(=O)F.Cc1cc(O)cc(C)c1N=Cc1ccccc1O>>Cc1cc(OC(=O)N(C)SSC(C)(C)C)cc(C)c1N=Cc1ccccc1O -US07977485B2,2,CCOCCCN.O=C(O)c1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1>>CCOCCCNC(=O)c1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1 -US04273782,2,NCCCn1cc(Cc2ncc[nH]2)c2ccccc21.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(NCCCn1cc(Cc2ncc[nH]2)c2ccccc21)c1ccccc1 -US05225595,1,C#CCBr.CC(=O)Nc1ccc(S(=O)O)cc1>>C#CCS(=O)(=O)c1ccc(NC(C)=O)cc1 -US08034810B2,6,COC(=O)CN(Cc1ccc(OC)cc1)S(=O)(=O)c1ccc(OCCCCF)cc1>>COc1ccc(CN(CC(=O)O)S(=O)(=O)c2ccc(OCCCCF)cc2)cc1 -US20150133512A1,6,COC(=O)C1(c2ccc(-c3ccc(-n4nncc4NC(=O)O[C@H](C)c4ccccc4)cc3)cc2)CC1>>C[C@@H](OC(=O)Nc1cnnn1-c1ccc(-c2ccc(C3(C(=O)O)CC3)cc2)cc1)c1ccccc1 -US20140163033A1,2,CC(C)(C)OC(=O)NC(C(=O)O)C(F)(F)F.Nn1cccc1C(=O)Nc1ccccc1>>CC(C)(C)OC(=O)NC(C(=O)Nn1cccc1C(=O)Nc1ccccc1)C(F)(F)F -US05736540,2,Cc1ccccc1C(=O)N(C)c1ccc(C(=O)Cl)cc1.c1ccc2c(c1)Cn1cccc1CN2>>Cc1ccccc1C(=O)N(C)c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 -US20130267541A1,6,CC(C)(C)OC(=O)N[C@H]1C[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)cnc21>>N[C@H]1C[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)cnc21 -US20030187023A1,2,O=C(Cl)OCc1ccccc1.OC[C@H]1CCCN1>>O=C(OCc1ccccc1)N1CCC[C@@H]1CO -US04695582,6,CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)CCSC(=O)[C@@H](N)Cc1ccccc1C(=O)c1ccccc1>>N[C@@H](Cc1ccccc1C(=O)c1ccccc1)C(=O)SCCC(=O)N1CCC[C@H]1C(=O)O -US04444775,6,CCOC(=O)CCCCCc1cccc2cncn12>>O=C(O)CCCCCc1cccc2cncn12 -US20140114068A1,2,CCc1cccc2c1OC1(O)c3ccccc3C(=O)C21N.O=C(O)c1ccc[nH]1>>CCc1cccc2c1OC1(O)c3ccccc3C(=O)C21NC(=O)c1ccc[nH]1 -US20110086834A1,1,CNCCOC.O=[N+]([O-])c1cc(I)ccc1F>>COCCN(C)c1ccc(I)cc1[N+](=O)[O-] -US06350749B1,1,Cc1ccnc2c1C(=O)CC(c1ccsc1Br)C2.N=C(NN)NO>>Cc1ccnc2c1C(=NNC(=N)NO)CC(c1ccsc1Br)C2 -US20110124665A1,1,COC(=O)CCCc1ccc(N)cc1.COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1>>COC(=O)CCCc1ccc(Nc2ncnc3oc(-c4ccccc4)c(-c4ccc(OC)cc4)c23)cc1 -US06288096B1,1,CS(=O)(=O)OCCc1ccc(OS(C)(=O)=O)cc1.O=Cc1ccc(O)cc1>>CS(=O)(=O)Oc1ccc(CCOc2ccc(C=O)cc2)cc1 -US08399465B2,1,CC(=O)N1CC2CCC(C1)N2.ClCc1coc2cc(Oc3nc4ncccc4s3)ccc12>>CC(=O)N1CC2CCC(C1)N2Cc1coc2cc(Oc3nc4ncccc4s3)ccc12 -US08372875B2,3,NC(=O)c1cc(Br)cc2c(C3CCS(=O)(=O)CC3)c[nH]c12.OB(O)c1ccnc(Cl)c1>>NC(=O)c1cc(-c2ccnc(Cl)c2)cc2c(C3CCS(=O)(=O)CC3)c[nH]c12 -US08735620B2,7,COc1ccc(C=O)cc1O[Si](C)(C)C(C)(C)C>>COc1ccc(CO)cc1O[Si](C)(C)C(C)(C)C -US20100130446A1,9,Cc1cc(C(CC2CCCC2)c2ccc(S(C)(=O)=O)cc2)[nH]c1C(=O)O.N>>Cc1cc(C(CC2CCCC2)c2ccc(S(C)(=O)=O)cc2)[nH]c1C(N)=O -US08846664B2,3,CN1CCN(CCOc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1c(Br)cnc2c1N(Cc1c(F)ccc(F)c1Cl)CCN2>>Cc1c(-c2ccc(OCCN3CCN(C)CC3)cc2)cnc2c1N(Cc1c(F)ccc(F)c1Cl)CCN2 -US20110275797A1,6,CN1CCN(CCc2ccc(OCc3ccccc3)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)OC(C)(C)C)c2)CC1>>CN1CCN(CCc2ccc(O)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)OC(C)(C)C)c2)CC1 -US20110263593A1,6,CC(=O)Nc1ccc(Sc2cnc3ncccn23)cc1>>Nc1ccc(Sc2cnc3ncccn23)cc1 -US20130296312A1,1,COc1ccccc1CNc1cccn2nc(Cl)nc12.Cc1ccc(N)cn1>>COc1ccccc1CNc1cccn2nc(Nc3ccc(C)nc3)nc12 -US06924292B2,2,COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(C(=O)O)c1)=NC(C)(C)C2.N[C@H]1CNC1=O>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(C(=O)N[C@H]3CNC3=O)c1)=NC(C)(C)C2 -US06235731B1,7,COC(=O)CC1(C)Oc2c(C)c(C)c(C(C)(C)C)c(C)c2CC1O[SiH](C)C>>Cc1c(C)c(C(C)(C)C)c(C)c2c1OC(C)(CCO)C(O[SiH](C)C)C2 -US08063071B2,3,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1.COCCNCc1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cncc(CNCCOC)c4)cc23)CC1 -US20120178779A1,1,CI.Nc1ccc(OC(F)(F)F)cc1[N+](=O)[O-]>>CNc1ccc(OC(F)(F)F)cc1[N+](=O)[O-] -US07435744B2,2,Nc1ccc(C(F)(F)F)cc1.O=C(O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc(C(F)(F)F)cc1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1 -US20120202785A1,7,O=[N+]([O-])c1ccc(F)cc1Nc1ccccc1>>Nc1ccc(F)cc1Nc1ccccc1 -US20090247526A1,1,Cc1csc(N)n1.Clc1cc(OC2CCCCC2)ccn1>>Cc1csc(Nc2cc(OC3CCCCC3)ccn2)n1 -US20150141396A1,1,COCCCCl.Cn1cc(-c2cccc(-c3ncc(-c4cn[nH]c4)cn3)c2)cn1>>COCCCn1cc(-c2cnc(-c3cccc(-c4cnn(C)c4)c3)nc2)cn1 -US20040092543A1,6,COC(=O)c1cccc2c1c1c(OC)c3c(cc1n2Cc1ccccc1)CCCC3>>COC(=O)c1cccc2c1c1c(O)c3c(cc1n2Cc1ccccc1)CCCC3 -US06599890B1,2,COC(=O)[C@@H]1CCN[C@@H](C(=O)OC(C)(C)C)C1.COc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)[C@@H]1CCN(S(=O)(=O)c2ccc(OC)cc2)[C@@H](C(=O)OC(C)(C)C)C1 -US20100311966A1,2,CCCNC1CN(c2nc(C(C)C)c(C(=O)OCC)s2)C1.CCc1[nH]c(C(=O)O)nc1Cl>>CCCN(C(=O)c1nc(Cl)c(CC)[nH]1)C1CN(c2nc(C(C)C)c(C(=O)OCC)s2)C1 -US08697685B2,1,C1CCNCC1.Nc1nc(Cl)cc(Cl)n1>>Nc1nc(Cl)cc(N2CCCCC2)n1 -US20040248941A1,8,COCC(COC)OC(=O)OC(C)n1c(SCc2nccc(OCC(F)(F)F)c2C)nc2ccccc21.O=C(OO)c1cccc(Cl)c1>>COCC(COC)OC(=O)OC(C)n1c(S(=O)Cc2nccc(OCC(F)(F)F)c2C)nc2ccccc21 -US08044068B2,6,CC(C)(C)OC(=O)N1CCN(c2nc(N[C@H]3CCN(C(=O)Cc4ccc(Cl)cc4)C3)nc3ccccc23)CC1>>O=C(Cc1ccc(Cl)cc1)N1CC[C@H](Nc2nc(N3CCNCC3)c3ccccc3n2)C1 -US07615557B2,2,Clc1ccccc1N1CCNCC1.O=C([O-])Nc1cccc2c1CC(O)CC2>>O=C(Nc1cccc2c1CC(O)CC2)N1CCN(c2ccccc2Cl)CC1 -US08067583B2,6,Cc1ncoc1C(=O)c1ccccc1C(C)C#C[Si](C)(C)C>>C#CC(C)c1ccccc1C(=O)c1ocnc1C -US20120022069A1,3,CC(C)(C)OC(=O)N1CCCC(=O)C1.COP(=O)(CC(=O)OC(C)(C)C)OC>>CC(C)(C)OC(=O)/C=C1/CCCN(C(=O)OC(C)(C)C)C1 -US20120022069A1,3,CC(C)(C)OC(=O)N1CCCC(=O)C1.COP(=O)(CC(=O)OC(C)(C)C)OC>>CC(C)(C)OC(=O)/C=C1\CCCN(C(=O)OC(C)(C)C)C1 -USRE045183E1,7,O=Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1>>O=C(Nc1ncc(CO)s1)N(C1CCCCC1)C1CCCCC1 -US04436918,2,O=C1CC(C(NC(=O)OCc2ccccc2)C(=O)O)C(=O)N1.OCC(Cl)(Cl)Cl>>O=C1CC(C(NC(=O)OCc2ccccc2)C(=O)OCC(Cl)(Cl)Cl)C(=O)N1 -US20030078277A1,6,Cc1cc(C)c(-c2c(C)nn3c4c(c(C)nc23)CCN4Cc2ccccc2)c(C)c1>>Cc1cc(C)c(-c2c(C)nn3c4c(c(C)nc23)CCN4)c(C)c1 -US20110237791A1,7,CC(C)(C)c1ccc(/C(=C\[C@H]2CCC(=O)N2)c2ccc(OC(F)F)c(=O)[nH]2)cc1>>CC(C)(C)c1ccc(C(C[C@H]2CCC(=O)N2)c2ccc(OC(F)F)c(=O)[nH]2)cc1 -US08314113B2,1,COC(=O)C1CCNCC1.Cc1cc(Br)ccc1F>>COC(=O)C1CCN(c2ccc(F)c(C)c2)CC1 -US20150266819A1,2,COc1ccc(C(=O)O)cc1[N+](=O)[O-].COc1ccc(CCN)cc1>>COc1ccc(CCNC(=O)c2ccc(OC)c([N+](=O)[O-])c2)cc1 -US06191275B1,3,C[Zn+].O=C(Cl)c1cc([N+](=O)[O-])c(F)cc1Cl>>CC(=O)c1cc([N+](=O)[O-])c(F)cc1Cl -US20140135318A1,7,CCCCc1c(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(C(=O)OCC)nn1-c1ccccc1>>CCCCc1c(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(CO)nn1-c1ccccc1 -US07300935B2,6,CCOC(=O)c1c(N(Cc2c(F)cccc2F)C(=O)OCC)sc(-c2ccc(NC(=O)NOC)cc2)c1CN(C)Cc1ccccc1>>CCOC(=O)c1c(N(Cc2c(F)cccc2F)C(=O)OCC)sc(-c2ccc(NC(=O)NOC)cc2)c1CNC -US20150191464A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(O)[C@H](F)CN>>CC(C)(C)OC(=O)NC[C@@H](F)C(C)(C)O -US20140088084A1,7,CC(C)(C)OC(=O)NC1=NC(c2cc([N+](=O)[O-])ccc2F)(C(F)F)COC1>>CC(C)(C)OC(=O)NC1=NC(c2cc(N)ccc2F)(C(F)F)COC1 -US20150265612A1,2,Cc1cccc(Oc2ccc(N)cn2)c1C.O=C(Cl)C1(c2ccc3c(c2)OCO3)CC1>>Cc1cccc(Oc2ccc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)cn2)c1C -US20070249588A1,2,C1CN2CC[C@H](C2)N1.O=C([O-])c1ncc(-c2cccnc2)o1>>O=C(c1ncc(-c2cccnc2)o1)N1CCN2CC[C@@H]1C2 -US20040138223A1,2,CCn1cc(CNc2ccc(C(C)C)cc2)cn1.O=C(O)C1CCCc2cc(OCc3ccccc3)ccc21>>CCn1cc(CN(C(=O)C2CCCc3cc(OCc4ccccc4)ccc32)c2ccc(C(C)C)cc2)cn1 -US07132425B2,2,O=C(O)c1cnc(Cl)cn1.OCCOC1CCCCO1>>O=C(OCCOC1CCCCO1)c1cnc(Cl)cn1 -US04966909,2,NNC(=O)c1ccc(Cl)cc1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)NNC(=O)c1ccc(Cl)cc1 -US20130237537A1,6,COC(=O)c1cncc2c1CCN(c1cccc(C(=O)Nc3cccc(C(C)C)c3)c1)C2>>CC(C)c1cccc(NC(=O)c2cccc(N3CCc4c(cncc4C(=O)O)C3)c2)c1 -US20140364433A1,1,Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.Clc1ncc2c(Br)cccc2n1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc3c(Br)cccc3n2)c1 -US20130281490A1,2,CCCCCCCOC(=O)N[C@@H](C(=O)O)[C@H](C)O>>CCCCCCCOC(=O)N[C@H]1C(=O)O[C@H]1C -US20150210687A1,6,COC(=O)c1ccc(-c2nn(Cc3c(Cl)cccc3C3(O)CCC3)c3cccc(F)c23)c(F)c1>>O=C(O)c1ccc(-c2nn(Cc3c(Cl)cccc3C3(O)CCC3)c3cccc(F)c23)c(F)c1 -US07279470B2,2,CN(C(=O)Cl)c1ccccc1.O=S(=O)(NCCC1CCCCC1)c1ccc(O)cc1>>CN(C(=O)Oc1ccc(S(=O)(=O)NCCC2CCCCC2)cc1)c1ccccc1 -US20070244125A1,1,CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1.COc1ccc(B(O)O)cc1>>COc1ccc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(C(=O)N4CCN(C(C)C)CC4)ccc32)cc1 -US07615568B2,2,CSc1ccc(C(=O)O)c(OC2CCN(C(=O)OC(C)(C)C)CC2)c1.Nc1cccnc1C(=O)Nc1ccc(Cl)cn1>>CSc1ccc(C(=O)Nc2cccnc2C(=O)Nc2ccc(Cl)cn2)c(OC2CCN(C(=O)OC(C)(C)C)CC2)c1 -US04062862,1,CCCI.O=C1NCC(Cc2ccccc2)O1>>CCCN1CC(Cc2ccccc2)OC1=O -US20080275025A1,1,CCCCCCCCCCCCCC(=O)O.CO[C@@H](C(=O)N[C@H]1CC[C@@H](O)CN(Cc2cccnc2)C1=O)[C@@H]1OC(C)(C)O[C@H](/C=C/C(C)(C)C)[C@H]1O>>CCCCCCCCCCCCCC(=O)O[C@@H]1CC[C@H](NC(=O)[C@H](OC)[C@@H]2OC(C)(C)O[C@H](/C=C/C(C)(C)C)[C@H]2O)C(=O)N(Cc2cccnc2)C1 -US08685959B2,6,C[C@@H]1CN(c2ccc3ncn([C@H](C)c4ccc(Cl)cc4Cl)c3c2)CCN1C(=O)[C@H]1CCCN1C(=O)OC(C)(C)C>>C[C@@H]1CN(c2ccc3ncn([C@H](C)c4ccc(Cl)cc4Cl)c3c2)CCN1C(=O)[C@H]1CCCN1 -US20100069380A1,1,Nc1ccccc1.O=C1CCc2ccccc21>>c1ccc(N=C2CCc3ccccc32)cc1 -US20100130538A1,7,COC(=O)c1ccc(F)c2nn(C)cc12>>Cn1cc2c(CO)ccc(F)c2n1 -US08350090B1,6,CC(=O)O[C@H]1C=C(Cc2cccc(OCc3ccccc3)c2)C(=O)C1>>O=C1C[C@@H](O)C=C1Cc1cccc(OCc2ccccc2)c1 -US20110118262A1,2,Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)cc1C(=O)O.N=C(N)NC(=O)OCc1ccccc1>>Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)cc1C(=O)N(C(=N)N)C(=O)OCc1ccccc1 -US20080292626A1,9,CC(C)[C@@H](N=[N+]=[N-])c1nc2c(oc3ccccc32)c(=O)n1Cc1ccccc1>>CC(C)[C@@H](N)c1nc2c(oc3ccccc32)c(=O)n1Cc1ccccc1 -US20060264460A1,1,CCCCc1ncc(C=O)[nH]1.N#Cc1cnc2c(Br)cc(N)cc2c1Nc1ccc(F)c(Cl)c1>>CCCCc1ncc(CNc2cc(Br)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)[nH]1 -US06159997,6,CC(=O)Oc1c(C)cc(N(C)C(=O)OC(C)(C)C)c(C)c1C>>CNc1cc(C)c(OC(C)=O)c(C)c1C -US08697723B2,1,BrCc1ccccc1.CS(=O)(=O)OC[C@H]1COc2c(O)cccc2O1>>CS(=O)(=O)OC[C@H]1COc2c(OCc3ccccc3)cccc2O1 -US20130310384A1,1,COC(=O)c1ccc(CBr)cc1.C[C@H](O)[C@H](CO)NS(=O)(=O)c1ccc(Cl)cc1>>COC(=O)c1ccc(CN([C@H](CO)[C@@H](C)O)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20120040954A1,9,BrC(Br)(Br)Br.COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCO)c(C)c3)nc2n1>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCBr)c(C)c3)nc2n1 -US20060160885A1,6,CCC(=O)CN([C@H]1CCN([C@@H](C)C(=O)OC(C)(C)C)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1>>CCC(=O)CN([C@H]1CCN([C@@H](C)C(=O)O)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1 -US20070155805A1,7,CCOC(=O)/C=C/c1sc2cc(Br)ccc2c1C>>CCOC(=O)CCc1sc2cc(Br)ccc2c1C -US20090181945A1,2,C=CCC(=O)O.C=C[C@@H]1CCC[C@H](c2ccccc2F)N1>>C=CCC(=O)N1[C@H](C=C)CCC[C@@H]1c1ccccc1F -US20080058521A1,1,CN(C(=O)OC(C)(C)C)C1CCC(N)CC1.COc1ccc(-c2cccnc2F)cc1C=O>>COc1ccc(-c2cccnc2F)cc1CNC1CCC(N(C)C(=O)OC(C)(C)C)CC1 -US20090023753A1,1,CN.OCc1ccnc(Cl)c1>>CNc1cc(CO)ccn1 -US20060270869A1,2,NC(C(=O)O)C(c1ccc(F)cc1)c1ccc(F)cc1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)NC(C(=O)O)C(c1ccc(F)cc1)c1ccc(F)cc1 -US20110230467A1,1,CCOC(=O)c1cnc(Cl)cc1Cl.CSc1ccccc1N>>CCOC(=O)c1cnc(Cl)cc1Nc1ccccc1SC -US06797823B1,1,CN1CCNCC1.COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(Cl)c3)ncnc2cc1OCCCBr>>COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(Cl)c3)ncnc2cc1OCCCN1CCN(C)CC1 -US20130345120A1,2,CCCC[C@H](CN(C=O)OCc1ccccc1)C(=O)N1[C@H](C(=O)O)CCN1C(=O)OCc1ccccc1.Nc1ccccn1>>CCCC[C@H](CN(C=O)OCc1ccccc1)C(=O)N1[C@H](C(=O)Nc2ccccn2)CCN1C(=O)OCc1ccccc1 -US20130231333A1,1,OB(O)c1ccccc1.Oc1ccc(Br)c(Cl)c1>>Clc1cc(Oc2ccccc2)ccc1Br -US20100331326A1,1,COc1ccc2cc(Br)ccc2c1.Cc1ccncc1N1CCNC1=O>>COc1ccc2cc(N3CCN(c4cnccc4C)C3=O)ccc2c1 -US20040038962A1,2,Cc1cc(C(=O)O)ccc1C#N.c1ccc2c(c1)NCCCS2>>Cc1cc(C(=O)N2CCCSc3ccccc32)ccc1C#N -US07479496B2,2,Cn1nnnc1-c1cccc(N)c1.O=C(Cl)Oc1ccccc1>>Cn1nnnc1-c1cccc(NC(=O)Oc2ccccc2)c1 -US20080306107A1,2,Cc1cc(C(F)(F)F)c2c(N)c(C(=O)O)sc2n1.Cc1ccc(CCN)cc1>>Cc1ccc(CCNC(=O)c2sc3nc(C)cc(C(F)(F)F)c3c2N)cc1 -US20120065184A1,1,Clc1ccc2nccn2n1.Fc1cccc([C@H]2CC(F)(F)CN2)c1>>Fc1cccc([C@H]2CC(F)(F)CN2c2ccc3nccn3n2)c1 -US20120178736A1,1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1.OC1CCN(C2CNC2)CC1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(N4CCC(O)CC4)C3)n(C)c2n1 -US20140275152A1,3,COc1ccc(B(O)O)cc1.OCc1cccnc1Cl>>COc1ccc(-c2ncccc2CO)cc1 -US20090318493A1,8,CC(C)(C)CCC1(C(O)c2csc3ccc(F)cc23)CCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)CCC1(C(=O)c2csc3ccc(F)cc23)CCN(C(=O)OC(C)(C)C)C1 -US20140378474A1,6,Cc1cnc2[nH]cc(CNC(=O)OC(C)(C)C)c2c1>>Cc1cnc2[nH]cc(CN)c2c1 -US20140213580A1,8,Clc1cccc2nccnc12.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccnc2c(Cl)cccc21 -US20110015157A1,2,CC(C)(C)C(=O)O.C[C@@H](c1ccc(Br)cc1)N1CC[C@](CC(C)(C)N)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(Br)cc1)N1CC[C@](CC(C)(C)NC(=O)C(C)(C)C)(c2ccccc2)OC1=O -US20130029964A1,1,Brc1ccc(-n2cnc3ccccc32)cc1.NCCOCCO>>OCCOCCNc1ccc(-n2cnc3ccccc32)cc1 -US08829026B2,7,Cn1ccc2cc(C#N)cnc21>>Cn1ccc2cc(CN)cnc21 -US06248754B1,6,CCOc1ccc(C(=O)Nc2ccc3c(c2Cl)CN(C(=O)C(F)(F)F)CC3)cc1Br>>CCOc1ccc(C(=O)Nc2ccc3c(c2Cl)CNCC3)cc1Br -US20090099183A1,2,CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)OC(C)(C)C.CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(CO)cc2)nc(N)n1>>CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(COC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc2)nc(N)n1 -US20070054903A1,3,CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C.Cc1cc(Br)c(N)c(C(N)=O)c1>>Cc1cc(C(N)=O)c(N)c(-c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)c1 -US20120157460A1,1,Cn1c2c(c3ccc(Br)nc31)CN(C(=O)OC(C)(C)C)CC2.O=C1CN(CCc2ccccc2)CCN1>>Cn1c2c(c3ccc(N4CCN(CCc5ccccc5)CC4=O)nc31)CN(C(=O)OC(C)(C)C)CC2 -US06245761B1,1,CC(C)(CCCO)NC(=O)OC(C)(C)C.Fc1ccc(Br)cc1CBr>>CC(C)(CCCOCc1cc(Br)ccc1F)NC(=O)OC(C)(C)C -US05827863,9,Fc1cc(Br)ccc1CBr.[C-]#N>>N#CCc1ccc(Br)cc1F -US03965095,2,C=CCNCC(O)COc1cccc2c1CC(=O)N2.O=C(O)C12CC3CC(CC(C3)C1)C2>>C=CCNCC(COc1cccc2c1CC(=O)N2)OC(=O)C12CC3CC(CC(C3)C1)C2 -US20070117836A1,2,CN(C)CCN1C(=O)c2cccc3cc(N)cc(c23)C1=O.FC(F)(F)Oc1ccc(N=C=S)cc1>>CN(C)CCN1C(=O)c2cccc3cc(NC(=S)Nc4ccc(OC(F)(F)F)cc4)cc(c23)C1=O -US06855722B2,1,Brc1cncc(Br)c1.OCC(F)(F)F>>FC(F)(F)COc1cncc(Br)c1 -US04994461,1,COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCBr)C1c1cccc([N+](=O)[O-])c1.c1ccc(C2(c3ccccc3)CCNCC2)cc1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1 -US04154756,1,CC(C)(C)CCCC(=O)CCCCCCCCCCBr.CCOC(=O)c1ccc(N)cc1>>CCOC(=O)c1ccc(NCCCCCCCCCCC(=O)CCCC(C)(C)C)cc1 -US20050154042A1,7,COCc1ccc(C#N)cc1>>COCc1ccc(CN)cc1 -US06063782,1,CC=CCn1c(C)c(C)c2cnnc(Cl)c21.OCc1ccco1>>CC=CCn1c(C)c(C)c2cnnc(OCc3ccco3)c21 -US20110082181A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1CO>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CO)cc3)cc2)CC1 -US20100144715A1,1,BrCCCOC1CCCCO1.O=[N+]([O-])c1ccc(F)cc1O>>O=[N+]([O-])c1ccc(F)cc1OCCCOC1CCCCO1 -US05231102,2,CC(C)(C)OC(=O)NCc1cccc(C(=O)O)c1.COC(=O)C1CC(N)c2c(Cl)cc(Cl)cc2N1>>COC(=O)[C@H]1C[C@H](NC(=O)c2cccc(CNC(=O)OC(C)(C)C)c2)c2c(Cl)cc(Cl)cc2N1 -US20060069116A1,1,CC(C)(C)OC(=O)N1CC[C@@H](N=[N+]=[N-])[C@H](OS(C)(=O)=O)C1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CC[C@H](N=[N+]=[N-])[C@H](N=[N+]=[N-])C1 -US20130116442A1,1,CNC(=O)c1cc(Cl)ccn1.Nc1ccc(O)cc1F>>CNC(=O)c1cc(Oc2ccc(N)c(F)c2)ccn1 -US20140171315A1,1,O=C1CCc2cc(/C=C/C(c3cc(Cl)c(Cl)c(Cl)c3)C(F)(F)F)ccc21.[NH4+]>>NC1CCc2cc(/C=C/C(c3cc(Cl)c(Cl)c(Cl)c3)C(F)(F)F)ccc21 -US04782050,2,CC(=O)Cl.c1ccc(-c2c[nH]cn2)cc1>>CC(=O)n1cnc(-c2ccccc2)c1 -US07713994B2,3,C=O.NC(=O)Cc1ccccc1>>O=C1Cc2ccccc2CN1 -US20110212968A1,2,Fc1ccc2[nH]cc(CCNCC3CC3)c2c1.O=C(O)c1ncccc1Br>>O=C(c1ncccc1Br)N(CCc1c[nH]c2ccc(F)cc12)CC1CC1 -US05223536,7,N#CC(=CCC(c1ccc(Cl)cc1)C1CC1)c1cccc(Oc2ccccc2)c1>>N#CC(CCC(c1ccc(Cl)cc1)C1CC1)c1cccc(Oc2ccccc2)c1 -US20040019046A1,2,CC(C(=O)O)c1ccc(N2CCCC2=O)cc1.CC(C)(C)OC(=O)n1nc(C2CC2)cc1N>>CC(C(=O)Nc1cc(C2CC2)nn1C(=O)OC(C)(C)C)c1ccc(N2CCCC2=O)cc1 -US20030181726A1,1,CC[Si](CC)(CC)O[C@@H](CI)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1.COc1ccc(C(CC(C)NCc2ccccc2)c2ccc(OC)cc2)cc1>>CC[Si](CC)(CC)O[C@@H](CN(Cc1ccccc1)C(C)CC(c1ccc(OC)cc1)c1ccc(OC)cc1)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1 -US20110190227A1,2,CC(C)C(=O)Cl.CCOC(=O)Cc1ccc(OC)c(Oc2ccc(N)cc2CSCC(F)(F)F)c1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(NC(=O)C(C)C)cc2CSCC(F)(F)F)c1 -US20120035164A1,1,CCOCCCN.O=Cc1ccc(B(O)O)s1>>CCOCCCNCc1ccc(B(O)O)s1 -US20040077655A1,7,O=C(O)Cc1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(CCO)ccc1F -US20120289522A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1C(O)C(=O)N[C@H](C)c1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C(=O)N[C@H](C)c4ccccc4)cc3)cc2)CC1 -US04188484,2,Cc1cccc(Nc2cc(Cl)nc(SCC(=O)O)n2)c1C.NCCO>>Cc1cccc(Nc2cc(Cl)nc(SCC(=O)NCCO)n2)c1C -US20070043048A1,6,c1ccc(CN2CCC(Nc3nccc(-c4cc5ccccc5s4)n3)CC2)cc1>>c1ccc2sc(-c3ccnc(NC4CCNCC4)n3)cc2c1 -US20130196974A1,7,N#CC1(N(Cc2ccccc2)Cc2ccccc2)CCOC1>>NCC1(N(Cc2ccccc2)Cc2ccccc2)CCOC1 -US06531485B2,3,CCCC[Sn](C=C[C@@H]1CCC(=O)[C@H]1CCCCCCC(=O)OC)(CCCC)CCCC.O=C(Cl)c1ccccc1>>COC(=O)CCCCCC[C@@H]1C(=O)CC[C@H]1C=CC(=O)c1ccccc1 -US05859007,6,CC(C)N(C(=O)CN1C(=O)C(Cc2nn(C(=O)OC(C)(C)C)c3ccccc23)C(=O)N(c2ccccc2)c2ccccc21)c1ccc2c(c1)OCO2>>CC(C)N(C(=O)CN1C(=O)C(Cc2n[nH]c3ccccc23)C(=O)N(c2ccccc2)c2ccccc21)c1ccc2c(c1)OCO2 -US20070149570A1,3,O=Cc1cc(Br)ccc1OC(F)(F)F.OB(O)c1ccc(F)cc1Cl>>O=Cc1cc(-c2ccc(F)cc2Cl)ccc1OC(F)(F)F -US07022860B2,7,CCOC(=O)c1nn(COC(=O)OC(C)C)nc1C(=O)c1cc(OC)c(OC)cc1[N+](=O)[O-]>>CCOC(=O)c1nn(COC(=O)OC(C)C)nc1C(=O)c1cc(OC)c(OC)cc1N -US20080113963A1,2,CN.Cc1nc2c3c(c(C(=O)O)cc2n1C)CCC(c1ccccc1)N3>>CNC(=O)c1cc2c(nc(C)n2C)c2c1CCC(c1ccccc1)N2 -US20030166936A1,6,CCOC(=O)c1cn(C2CC2)c2c(F)c(Cl)c(F)c(NCc3ccccc3)c2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(F)c(Cl)c(F)c(N)c2c1=O -US05874194,2,CS(N)(=O)=O.O=C(Cl)c1ccc(CCBr)cc1>>CS(=O)(=O)NC(=O)c1ccc(CCBr)cc1 -US20110190278A1,4,C=CCCN1C(=O)C(C)(C)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc21.O=C(OO)c1cccc(Cl)c1>>CC(C)N(C(=O)c1cc2c(cc1C(F)(F)F)OC(C)(C)C(=O)N2CCC1CO1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1 -US20050043358A1,9,O=C1N[C@@H](Cc2ccc(Oc3cccc(Cl)n3)cc2)CO1>>O=C1N[C@@H](Cc2ccc(Oc3ccccn3)cc2)CO1 -US20140336224A1,2,CCC(C#N)(c1ccc(Cl)cc1)c1n[nH]c2c(N)cccc12.CS(=O)(=O)Cl>>CCC(C#N)(c1ccc(Cl)cc1)c1n[nH]c2c(NS(C)(=O)=O)cccc12 -US05998433,6,COC(=O)c1cc2c(o1)CN(C(=O)CCCCCc1ccccc1)CC2>>O=C(O)c1cc2c(o1)CN(C(=O)CCCCCc1ccccc1)CC2 -US05011932,1,CC(=O)c1ccncc1.NNC(=O)Oc1ccccc1>>CC(=NNC(=O)Oc1ccccc1)c1ccncc1 -US20100081686A1,6,CCCCn1c2c(cc(NC(=O)OCc3ccccc3)c1=O)CCCC2>>CCCCn1c2c(cc(N)c1=O)CCCC2 -US20060281789A1,2,CC(=O)OC(C)=O.Nc1ccc(/C=C/c2n[nH]c3ccccc23)cc1>>CC(=O)Nc1ccc(/C=C/c2n[nH]c3ccccc23)cc1 -US20110086860A1,1,CCOC(=O)/C(=C/c1ccc(-n2cnc(C)c2)c(OC)c1)CCCCl.COc1ccc2c(c1)C(N)CCC2>>CCOC(=O)/C(=C/c1ccc(-n2cnc(C)c2)c(OC)c1)CCCNC1CCCc2ccc(OC)cc21 -US20050119491A1,1,Brc1ccc2c(c1)[nH]c1cc(Br)ccc12.CCCCCCCCCCCCBr>>CCCCCCCCCCCCn1c2cc(Br)ccc2c2ccc(Br)cc21 -US08431563B2,7,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)O)C1>>CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](CO)C1 -US20130217715A1,3,COCN(c1cccc(-c2nn(C3CCCCO3)cc2B2OC(C)(C)C(C)(C)O2)c1F)S(=O)(=O)c1cc(F)ccc1F.Nc1nccc(Cl)n1>>COCN(c1cccc(-c2nn(C3CCCCO3)cc2-c2ccnc(N)n2)c1F)S(=O)(=O)c1cc(F)ccc1F -US20120302547A1,6,CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccc(-n3ccc4cc(-c5ccc(Cl)cc5)sc4c3=O)cc2)C1>>O=C(Nc1ccc(-n2ccc3cc(-c4ccc(Cl)cc4)sc3c2=O)cc1)C1CCNC1 -US03980797,6,c1ccc(CN2CCCN3c4ccccc4CC3C2)cc1>>c1ccc2c(c1)CC1CNCCCN21 -US05266570,7,Nc1nc(NC2CCN(CC34CC(c5ccccc53)c3ccccc34)CC2)ncc1[N+](=O)[O-]>>Nc1cnc(NC2CCN(CC34CC(c5ccccc53)c3ccccc34)CC2)nc1N -US08318757B2,6,O=C1c2ccccc2C(=O)N1Cc1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1Cl>>NCc1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1Cl -US08183262B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Fc1ccc(-c2cc(C(F)(F)F)nc(-n3cnc(I)c3)n2)cc1>>Nc1ccc(-c2cn(-c3nc(-c4ccc(F)cc4)cc(C(F)(F)F)n3)cn2)cn1 -US04228298,1,C#CCC(CCCC)(O[Si](C)(C)C)C(F)(F)F.CCCC[SnH](CCCC)CCCC>>CCCCC(C/C=C/[Sn](CCCC)(CCCC)CCCC)(O[Si](C)(C)C)C(F)(F)F -US20140155419A1,2,Cc1ccc(C(N)c2ccccc2)c(C)c1.Cc1ncccc1CNC1(C)CCN(CC(=O)O)CC1>>Cc1ccc(C(NC(=O)CN2CCC(C)(NCc3cccnc3C)CC2)c2ccccc2)c(C)c1 -US05310724,9,CCN(CC)c1cc(F)c(N)cc1F.S=C(Cl)Cl>>CCN(CC)c1cc(F)c(N=C=S)cc1F -US20110124643A1,6,CCOC(=O)Cc1ccc(-c2ccc3c(=O)c(C(=O)NC)c(N)n(CC)c3n2)cc1>>CCn1c(N)c(C(=O)NC)c(=O)c2ccc(-c3ccc(CC(=O)O)cc3)nc21 -US07704996B2,6,O=C1c2ccccc2C(=O)N1CC(CN1CCCC1)c1ccccc1>>NCC(CN1CCCC1)c1ccccc1 -US06288082B1,1,COc1ccc2c(Cl)c(C#N)cnc2c1.Nc1ccc2cn[nH]c2c1>>COc1ccc2c(Nc3ccc4cn[nH]c4c3)c(C#N)cnc2c1 -US20110046147A1,3,Brc1csc(Br)c1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cc(Br)cs2)cc1 -US20100130737A1,6,COC(=O)[C@H](Cc1ccc(OCc2ccoc2)cc1)NC(=O)c1oc2cc(-c3ccc(Cl)cc3)ccc2c1C>>Cc1c(C(=O)N[C@@H](Cc2ccc(OCc3ccoc3)cc2)C(=O)O)oc2cc(-c3ccc(Cl)cc3)ccc12 -US20080249125A1,1,CNC(=O)C(Br)c1ccccc1.COc1ccc(CCC2NCCc3sc(C)c(C)c32)cc1>>CNC(=O)C(c1ccccc1)N1CCc2sc(C)c(C)c2C1CCc1ccc(OC)cc1 -US20140364436A1,3,C#Cc1ccc(NC(C)C)nn1.Cc1cn(-c2ccc(NC(=O)c3ccc(Cl)c(I)c3)cc2C(F)(F)F)cn1>>Cc1cn(-c2ccc(NC(=O)c3ccc(Cl)c(C#Cc4ccc(NC(C)C)nn4)c3)cc2C(F)(F)F)cn1 -US07700591B2,7,COC(=O)c1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)ccc1F>>COC(=O)c1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1F -US06140270,8,COc1ccccc1C(O)c1cc([N+](=O)[O-])ccc1Cl>>COc1ccccc1C(=O)c1cc([N+](=O)[O-])ccc1Cl -US20080132551A1,3,CCCC[Sn](CCCC)(CCCC)c1ncco1.CCOc1ccc(N)c(Br)c1>>CCOc1ccc(N)c(-c2ncco2)c1 -US20010051657A1,6,COC(=O)CC(=O)Nc1cc(C)c(Oc2ccc(O)c(S(=O)(=O)c3ccc(F)cc3)c2)c(C)c1>>Cc1cc(NC(=O)CC(=O)O)cc(C)c1Oc1ccc(O)c(S(=O)(=O)c2ccc(F)cc2)c1 -US20070238700A1,1,CC(=O)c1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F.COC(=O)NN>>COC(=O)NN=C(C)c1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F -US04055641,7,CCC(=O)OC[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@H](OC(=O)CC)[C@@]3(C)CC[C@@H]12>>CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(CO)[C@H]3CC[C@]12C -US20140322355A1,4,CCC(=O)CBr.COC(=O)c1cc(C(=N)N)c(C2CCC2)cc1C>>CCc1cnc(-c2cc(C(=O)OC)c(C)cc2C2CCC2)[nH]1 -US05280027,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](CO)c1ccccc1>>CC(C)(C)OC(=O)NC(CO)c1ccccc1 -US20150158846A1,3,C=CC(=O)NCCN(C)c1cccc(Nc2cc(Br)cn(C)c2=O)n1.CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cc(F)cc1-n1ncc2c3c(sc2c1=O)CCCC3>>C=CC(=O)NCCN(C)c1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3COC(C)=O)cn(C)c2=O)n1 -US20110281835A1,6,COC1(c2cccc(F)c2F)CN(C(=O)OC(C)(C)C)C1>>COC1(c2cccc(F)c2F)CNC1 -US20150203447A1,2,CCCCN=C=O.COC(=O)C(C)c1ccc(-c2cccc(O)c2)c(F)c1>>CCCCNC(=O)Oc1cccc(-c2ccc(C(C)C(=O)OC)cc2F)c1 -US20060111351A1,2,CC1(c2ccc(S(=O)(=O)Cl)cc2)CCOCC1.Cc1ncccc1C(=O)c1cc(Cl)ccc1N>>Cc1ncccc1C(=O)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(C2(C)CCOCC2)cc1 -US03983164,2,CC(C)O.O=C(Cl)c1ccc(OCc2ccccc2)cc1>>CC(C)OC(=O)c1ccc(OCc2ccccc2)cc1 -US20080234318A1,2,CN1CCN(c2cccc3nc(CN(C)[C@H]4CCCc5cccnc54)c(CN)n23)CC1.COC(=O)Cl>>COC(=O)NCc1c(CN(C)[C@H]2CCCc3cccnc32)nc2cccc(N3CCN(C)CC3)n12 -US20110230497A1,2,CC(=O)N1CCC(C(C)(C)C(=O)O)CC1.Nc1ccc(-c2cc(F)cc(F)c2)cn1>>CC(=O)N1CCC(C(C)(C)C(=O)Nc2ccc(-c3cc(F)cc(F)c3)cn2)CC1 -US20100137627A1,2,CC(CCOC(=O)Cl)CCc1ccccc1.O=C(C=Cc1ccccc1O)OCCc1ccccc1>>CC(CCOC(=O)Oc1ccccc1C=CC(=O)OCCc1ccccc1)CCc1ccccc1 -US07432392B2,6,CC(C)(C)OC(=O)Nc1cc(F)c(OCc2ccccc2)c(F)c1C(=O)O>>Nc1cc(F)c(OCc2ccccc2)c(F)c1C(=O)O -US04851535,6,COC(=O)c1cc(F)c(N2CCC(NC(C)=O)C2)nc1Nc1ccc(F)cc1F>>CC(=O)NC1CCN(c2nc(Nc3ccc(F)cc3F)c(C(=O)O)cc2F)C1 -US07396844B1,6,COC(=O)c1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(C(=O)O)cc2)CC1 -US20150225367A1,3,O=S(=O)(c1ccccc1)n1cc(Br)c2ccc(F)cc21.OB(O)c1ccc(Cl)nc1>>O=S(=O)(c1ccccc1)n1cc(-c2ccc(Cl)nc2)c2ccc(F)cc21 -US08969343B2,1,Clc1ccc2[nH]nc(I)c2c1.FC(F)(F)CCI>>FC(F)(F)CCn1nc(I)c2cc(Cl)ccc21 -US05220020,7,CCCCCCC(C)=O>>CCCCCCC(C)O -US08809538B2,1,Brc1nn(C2CCCCO2)c2ccc(-c3ncn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc12.NCC1CCN(Cc2cc(-c3ccccc3)no2)CC1>>c1ccc(-c2cc(CN3CCC(CNc4nn(C5CCCCO5)c5ccc(-c6ncn(C(c7ccccc7)(c7ccccc7)c7ccccc7)n6)cc45)CC3)on2)cc1 -US20070179188A1,6,CCOC(=O)c1cccc(NC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)Nc1cccc(C(=O)O)c1 -US20110092476A1,2,C[C@H](C(=O)O)c1ccc(Cl)cc1.NC(=O)[C@@H](c1ccccc1)n1ccc2c(N)cccc2c1=O>>C[C@H](C(=O)Nc1cccc2c(=O)n([C@@H](C(N)=O)c3ccccc3)ccc12)c1ccc(Cl)cc1 -US05225422,6,CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)OC)n1>>CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)O)n1 -US06960578B2,3,CC(C)(C)OC(=O)Nc1ccc(I)cc1[N+](=O)[O-].COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c2)cc1 -US08431514B2,2,N#Cc1ccc(C(=O)O)cc1[N+](=O)[O-].Nc1c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc1Br>>N#Cc1ccc(C(=O)Nc2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc2Br)cc1[N+](=O)[O-] -US06352982B1,3,CC(C)(C)OC(=O)NCc1ccccc1Br.CON(C)C(=O)c1cc(Cl)ccc1N>>CC(C)(C)OC(=O)NCc1ccccc1C(=O)c1cc(Cl)ccc1N -US08415370B2,2,CCOCCN.O=C(O)c1ccc(CN2C(=O)C3(COc4cc5c(cc43)CCO5)c3ccccc32)cc1>>CCOCCNC(=O)c1ccc(CN2C(=O)C3(COc4cc5c(cc43)CCO5)c3ccccc32)cc1 -US20080221100A1,2,CS(=O)(=O)Cl.O=C(Nc1cccc(F)c1)NC1CCNCC1>>CS(=O)(=O)N1CCC(NC(=O)Nc2cccc(F)c2)CC1 -US20080207708A1,1,C1COCCN1.CC(C)COc1ccc(Cl)cc1Cc1nc(-c2nc3nc(Cl)ccc3[nH]2)cs1>>CC(C)COc1ccc(Cl)cc1Cc1nc(-c2nc3nc(N4CCOCC4)ccc3[nH]2)cs1 -US05948911,1,COC(=O)c1ccc(-c2nc(Cl)c3c4c(sc3n2)CCCC4)cc1.NCc1cccc([N+](=O)[O-])c1>>COC(=O)c1ccc(-c2nc(NCc3cccc([N+](=O)[O-])c3)c3c4c(sc3n2)CCCC4)cc1 -US20150141400A1,2,CC(C)(C)OC(=O)N1CCN(Cc2cc(N)c(C(=O)O)cc2C(F)(F)F)CC1.CCS(=O)(=O)c1ccc(C#N)cc1CN>>CCS(=O)(=O)c1ccc(C#N)cc1CNC(=O)c1cc(C(F)(F)F)c(CN2CCN(C(=O)OC(C)(C)C)CC2)cc1N -US06831075B2,3,Cn1cc(C=O)c2c(Br)cccc21.OB(O)c1ccccc1>>Cn1cc(C=O)c2c(-c3ccccc3)cccc21 -US04002749,3,O=C1Cc2ccccc2N1.O=Cc1cccs1>>O=C1Nc2ccccc2C1=Cc1cccs1 -US05595685,1,CCCCCCI.CCCCCCc1ccc(-c2ncc(-c3ccc(O)c(F)c3)s2)cc1>>CCCCCCOc1ccc(-c2cnc(-c3ccc(CCCCCC)cc3)s2)cc1F -US08436023B2,9,N.O=C(Cl)c1cc(C(F)(F)F)cnc1Cl>>NC(=O)c1cc(C(F)(F)F)cnc1Cl -US08642583B2,7,COc1ccccc1C(=O)C1CN(C(=O)OC(C)(C)C)C1>>COc1ccccc1CC1CN(C(=O)OC(C)(C)C)C1 -US20100010002A1,2,N#CCCN1CCNCC1.O=C(O)C=Cc1ccc(O)c(O)c1>>N#CCCN1CCN(C(=O)/C=C/c2ccc(O)c(O)c2)CC1 -US07714010B2,1,CCCCCN1C(=O)C(C)(C)c2cc3[nH]c(N)nc3cc21.CO>>CCCCCN1C(=O)C(C)(C)c2cc3[nH]c(NC)nc3cc21 -US07897766B2,2,NC1C2CC3CC1CN(C3)C2.O=C(O)c1cc2ccsc2s1>>O=C(NC1C2CC3CC1CN(C3)C2)c1cc2ccsc2s1 -US05821240,9,CCOC(=O)Cc1cccnc1.N>>NC(=O)Cc1cccnc1 -US20040087798A1,2,COc1ccc2c(c1)OCCC(C(=O)O)=C2.Nc1cccc(-n2ccnc2)c1>>COc1ccc2c(c1)OCCC(C(=O)Nc1cccc(-n3ccnc3)c1)=C2 -US20120316193A1,9,Cc1cc(C(=O)C(F)(F)Br)c(C)n1-c1ccc(Cl)cc1>>Cc1cc(C(=O)C(F)F)c(C)n1-c1ccc(Cl)cc1 -US05614517,7,COC(=O)/C=C/c1c2n(c(=O)c3cc(OC)ccc13)CCc1ccccc1-2>>COC(=O)CCc1c2n(c(=O)c3cc(OC)ccc13)CCc1ccccc1-2 -US20100075998A1,3,Cn1c(I)c(C(N)=O)c2c1-c1nc(N)ncc1CC2.OB(O)c1ccccc1>>Cn1c2c(c(C(N)=O)c1-c1ccccc1)CCc1cnc(N)nc1-2 -US07348357B2,2,CO.N[C@@H](CC(=O)O)c1ccccc1>>COC(=O)C[C@H](N)c1ccccc1 -US20130252882A1,3,COC(=O)c1cc(C2CC2)c2c(C)c(Cl)ccn2c1=O.COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O>>COC(=O)c1cc(C2CC2)c2c(C)c(-c3ccc(O)c(OC)c3)ccn2c1=O -US08999982B2,1,CCOC(=O)c1nn(-c2ccc(F)cc2)cc1O.CI>>CCOC(=O)c1nn(-c2ccc(F)cc2)cc1OC -US20130172318A1,2,NC1CCCCNC1=O.O=C(Cl)c1ccc(Cl)cc1>>O=C(NC1CCCCNC1=O)c1ccc(Cl)cc1 -US07759366B2,1,CN(C)C=O.Nc1ccc([N+](=O)[O-])cc1F>>CN(C)C=Nc1ccc([N+](=O)[O-])cc1F -US08399442B2,4,Nc1ccc(CN2CCOCC2)cc1N.O=C(O)c1n[nH]cc1[N+](=O)[O-]>>O=[N+]([O-])c1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1 -US20100093788A1,7,Nc1ccc(-c2c(F)cccc2C(F)(F)F)cc1[N+](=O)[O-]>>Nc1ccc(-c2c(F)cccc2C(F)(F)F)cc1N -US20090036495A1,2,COC(=O)c1ccc(CN)cc1.O=C(O)c1cc(C(F)(F)F)cnc1Oc1ccc(F)cc1>>COC(=O)c1ccc(CNC(=O)c2cc(C(F)(F)F)cnc2Oc2ccc(F)cc2)cc1 -US20100048568A1,2,CCOC(=O)CN(CCNN1C(=O)c2ccccc2C1=O)C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCN(N2C(=O)c3ccccc3C2=O)C(=O)C1 -US07615550B2,2,O=C(O)c1ccccc1.c1cc(OCCCN2CCCCC2)ccc1CN1CCNCC1>>O=C(c1ccccc1)N1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 -US07396960B2,1,C=COCCCl.Cc1cc([S+](c2ccccc2)c2ccccc2)cc(C)c1O>>C=COCCOc1c(C)cc([S+](c2ccccc2)c2ccccc2)cc1C -US06245761B1,1,CCN.Fc1ccc(Br)cc1COCCCCBr>>CCNCCCCOCc1cc(Br)ccc1F -US20140303149A1,1,COc1ccc(NC(=O)c2csc3cnc(Cl)nc23)cc1OC.N[C@H]1CCCC[C@H]1N>>COc1ccc(NC(=O)c2csc3cnc(N[C@@H]4CCCC[C@@H]4N)nc23)cc1OC -US20070219235A1,1,CN1CCNCC1.Nc1cc(Cl)c(C(=O)Nc2ccc3ncsc3c2)cc1[N+](=O)[O-]>>CN1CCN(c2cc(N)c([N+](=O)[O-])cc2C(=O)Nc2ccc3ncsc3c2)CC1 -US05214152,7,COC(=O)c1ccc(Cl)nc1>>OCc1ccc(Cl)nc1 -US20120214767A1,6,CCOC(=O)C[C@H]1CCCN(CC(O)c2ccc3c(c2)CCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1>>O=C(O)C[C@H]1CCCN(CC(O)c2ccc3c(c2)CCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1 -US08354398B2,6,CC(C)(C)OC(=O)C1CN(Cc2ccc(-c3noc(-c4noc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1>>O=C(O)C1CN(Cc2ccc(-c3noc(-c4noc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 -US06251911B1,1,Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12.O=Cc1ccc(-c2nnn[nH]2)cc1>>Clc1cccc(Nc2ncnc3[nH]nc(NCc4ccc(-c5nnn[nH]5)cc4)c23)c1 -US08685986B2,2,NCc1ccc(-c2ccccc2)nn1.O=S(=O)(Cl)c1cccnc1>>O=S(=O)(NCc1ccc(-c2ccccc2)nn1)c1cccnc1 -US20130281433A1,3,CC1(C)OB(c2ccc(OCc3ccccc3)nc2)OC1(C)C.CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(Cl)c3)sc2c1-c1ccc(Cl)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc(OCc5ccccc5)nc4)c3)sc2c1-c1ccc(Cl)cc1 -US20080176830A1,3,O=C1Nc2ccc(Br)cc2CC1O.O=S(=O)(c1ccc(Br)cc1)C(F)(F)F>>O=C1Nc2ccc(-c3ccc(S(=O)(=O)C(F)(F)F)cc3)cc2CC1O -US05688946,3,CC(C)(C)OC(=O)N1[C@@H](CC2CCCCC2)[C@H](C=O)OC1(C)C.CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CC/C=C\[C@H]1OC(C)(C)N(C(=O)OC(C)(C)C)[C@H]1CC1CCCCC1 -US20070049603A1,7,O=[N+]([O-])c1ccc(Cl)c(OCOCc2ccccc2)c1>>Nc1ccc(Cl)c(OCOCc2ccccc2)c1 -US07541365B2,2,CNC.O=C(O)COc1cccc2c1CC(=CCCN1CCC(O)(c3ccc(Cl)cc3)CC1)c1cccnc1O2>>CN(C)C(=O)COc1cccc2c1CC(=CCCN1CCC(O)(c3ccc(Cl)cc3)CC1)c1cccnc1O2 -US20080214533A1,1,CC(C)(C)[Si](C)(C)OCCCNc1ccc(NC(=O)c2nccnc2C(=O)Nc2ccc(Cl)cn2)cc1.N#CBr>>CC(C)(C)[Si](C)(C)OCCCN(C#N)c1ccc(NC(=O)c2nccnc2C(=O)Nc2ccc(Cl)cn2)cc1 -US08497368B2,3,CN(C)C=O.Cn1ncc2cc(Br)ccc21>>Cn1ncc2cc(C=O)ccc21 -US20040267010A1,8,CC(C)(C)OC(=O)N1CCC[C@@H]1CO>>CC(C)(C)OC(=O)N1CCC[C@@H]1C=O -US05747485,6,CCCC(NC(=O)N1C(=O)C(CC)(CC)C1Oc1ccc(C(=O)NCCN2CCC(OCc3ccccc3)CC2)cc1)c1ccc(C)cc1>>CCCC(NC(=O)N1C(=O)C(CC)(CC)C1Oc1ccc(C(=O)NCCN2CCC(O)CC2)cc1)c1ccc(C)cc1 -US20150225397A1,8,CC1C2CCCC(O)C2(Cc2ccccc2)CCC12OCCO2>>CC1C2CCCC(=O)C2(Cc2ccccc2)CCC12OCCO2 -US20140066427A1,6,COC(=O)C1CN(Cc2ccc(C(C)=CC(=O)c3cc(OC)c(OC)c(OC)c3)cc2)C1>>COc1cc(C(=O)C=C(C)c2ccc(CN3CC(C(=O)O)C3)cc2)cc(OC)c1OC -US04186135,7,O=C(O)c1cc([N+](=O)[O-])cc2c1OCCO2>>Nc1cc2c(c(C(=O)O)c1)OCCO2 -US20090054407A1,1,CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(C=O)ccc21.NCc1ccccc1>>CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(CNCc3ccccc3)ccc21 -US04873236,2,NCCN1CCCCC1CN1CCCCCC1.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>O=C1Nc2cccnc2N(C(=O)NCCN2CCCCC2CN2CCCCCC2)c2ccccc21 -US20100056530A1,4,CCC(=O)CBr.NC(=S)Nc1ncccc1OCc1ccccc1>>CCc1csc(Nc2ncccc2OCc2ccccc2)n1 -US05270331,2,NC(=O)N1C(=O)/C(=C(\O)c2cccs2)c2cc(F)c(Cl)cc21.O=C(Cl)c1ccco1>>NC(=O)N1C(=O)C(=C(OC(=O)c2ccco2)c2cccs2)c2cc(F)c(Cl)cc21 -US20050176775A1,1,COC(=O)c1ccc(-n2c(C)cc(O)cc2=O)c(Cl)c1.Fc1ccc(CBr)c(F)c1>>COC(=O)c1ccc(-n2c(C)cc(OCc3ccc(F)cc3F)cc2=O)c(Cl)c1 -US20060041123A1,6,COc1cc(F)c2ncc(NC(=O)OC(C)(C)C)c(Br)c2c1>>COc1cc(F)c2ncc(N)c(Br)c2c1 -US20060116410A1,3,Brc1ccccn1.COC(=O)c1cc(Cl)cc(B2OC(C)(C)C(C)(C)O2)c1>>COC(=O)c1cc(Cl)cc(-c2ccccn2)c1 -US04582525,2,C=Cc1ccccc1S(N)(=O)=O.O=C=Nc1nc(Cl)nc(Cl)n1>>C=Cc1ccccc1S(=O)(=O)NC(=O)Nc1nc(Cl)nc(Cl)n1 -US08367681B2,3,CN(C)C=O.Clc1ccn2nccc2n1>>O=Cc1cnn2ccc(Cl)nc12 -US07598236B2,1,Clc1ccc(Br)cn1.O=C(OCc1ccccc1)N1C[C@H]2NC[C@H]2C1>>O=C(OCc1ccccc1)N1C[C@@H]2[C@H](C1)CN2c1ccc(Cl)nc1 -US20040209921A1,10,Cc1cccnc1C#N.O=C1CCC(=O)N1Br>>N#Cc1ncccc1CBr -US07528137B2,2,CC(C)C(NCC(=O)CCN1C(=O)c2ccccc2C1=O)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1.Cc1ccc(C(=O)Cl)cc1>>Cc1ccc(C(=O)N(CC(=O)CCN2C(=O)c3ccccc3C2=O)C(c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1 -US20100324086A1,7,O=C(Nc1ccc(Br)cn1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(C(=O)Nc2ccc(Br)cn2)c1 -US07723368B2,3,C#Cc1ccc(OC(F)F)cc1.C=CCCC(F)c1cccc(I)c1>>C=CCCC(F)c1cccc(C#Cc2ccc(OC(F)F)cc2)c1 -US20140296515A1,2,CC(C)(C)OC(=O)NCCC(=O)O.CC(C)C[C@H](N)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1>>CC(C)C[C@H](NC(=O)CCNC(=O)OC(C)(C)C)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1 -US20110034445A1,2,Cn1ccnc1C(=NOCc1nccc(N)n1)c1ccccc1.O=C(O)C1CC1>>Cn1ccnc1C(=NOCc1nccc(NC(=O)C2CC2)n1)c1ccccc1 -US08765939B2,1,Cc1nc(N)nc(O)c1Br.OCc1ccc(S)cc1>>Cc1nc(N)nc(O)c1Sc1ccc(CO)cc1 -US07084156B2,7,CC(C)(C)OC(=O)C=Cc1ccc(C(F)(F)F)nc1>>CC(C)(C)OC(=O)CCc1ccc(C(F)(F)F)nc1 -US06894050B2,1,C1CNCCN1.Fc1cccc(COc2cncc(Cl)n2)n1>>Fc1cccc(COc2cncc(N3CCNCC3)n2)n1 -US07947727B2,2,CCNCC(O)(CNc1cc(C)cc2c1cnn2-c1ccccc1)C(F)(F)F.O=C(O)c1ccccc1Cl>>CCN(CC(O)(CNc1cc(C)cc2c1cnn2-c1ccccc1)C(F)(F)F)C(=O)c1ccccc1Cl -US08299085B2,2,CC(=O)Cl.CNc1cc(C(=O)OC)c(N)cc1C(F)(F)F>>COC(=O)c1cc(N(C)C(C)=O)c(C(F)(F)F)cc1N -US20070249670A1,6,CCOC(=O)C[C@H](NC(=O)c1ccc(-c2cccc(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)OCc1ccccc1>>CCOC(=O)C[C@H](NC(=O)c1ccc(-c2cccc(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)O -US20080312234A1,1,C#Cc1cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2Cl)cc(F)c1NS(C)(=O)=O.OC1CCOC1>>C#Cc1cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2OC2CCOC2)cc(F)c1NS(C)(=O)=O -US20120277208A1,1,COC(=O)c1cc(O)cc(O)c1.O=[N+]([O-])c1ccc(F)cc1>>COC(=O)c1cc(O)cc(Oc2ccc([N+](=O)[O-])cc2)c1 -US20050239789A1,1,CCOC(=O)C(C)=O.Cc1ccc(F)c(NN)c1>>CCOC(=O)C(C)=NNc1cc(C)ccc1F -US20080051405A1,1,CN1CCC(O)CC1.N#Cc1cccc(Br)n1>>CN1CCC(Oc2cccc(C#N)n2)CC1 -US20090163489A1,3,CC(=O)Nc1cn2nc(B3OC(C)(C)C(C)(C)O3)ccc2n1.O=S(=O)(Nc1cc(Br)cnc1Cl)c1ccc(F)cc1Cl>>CC(=O)Nc1cn2nc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4Cl)c3)ccc2n1 -US20150218124A1,6,COc1cc(C#N)c(Cc2ccc(C(C)C(=O)O)cc2)c(C#N)c1O>>CC(C(=O)O)c1ccc(Cc2c(C#N)cc(O)c(O)c2C#N)cc1 -US06329405B1,1,COc1cccc(C(=O)c2cccc([N+](=O)[O-])c2)c1.C[C@H](N)c1cccc(F)c1>>COc1cccc(C(N[C@@H](C)c2cccc(F)c2)c2cccc([N+](=O)[O-])c2)c1 -US20120108568A1,6,CC(C)(C)OC(=O)NC1(C(F)(F)F)CC1>>NC1(C(F)(F)F)CC1 -US07390903B2,9,O=C(CBr)c1ccc(F)cc1.[C-]#N>>N#CCC(=O)c1ccc(F)cc1 -US20090028873A1,3,C=O.CNC.O=C1CCCCC1>>CN(C)CC1CCCCC1=O -US20090115320A1,6,CC(=O)N(c1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4cccc5ccccc45)cc3)cc2)cc1)c1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4cccc5ccccc45)cc3)cc2)cc1>>c1ccc(N(c2ccc(-c3ccc(-c4ccc(Nc5ccc(-c6ccc(-c7ccc(N(c8ccccc8)c8cccc9ccccc89)cc7)cc6)cc5)cc4)cc3)cc2)c2cccc3ccccc23)cc1 -US20040259843A1,1,C#C[C@H]1CC[C@@H](C#N)N1C(=O)CCl.CCC(C)(C)N>>C#C[C@H]1CC[C@@H](C#N)N1C(=O)CNC(C)(C)CC -US20070208033A1,2,CCCN(CCC)CCCCN.Cn1ccnc1CN(Cc1ccc(C(=O)O)cc1)Cc1nccn1C>>CCCN(CCC)CCCCNC(=O)c1ccc(CN(Cc2nccn2C)Cc2nccn2C)cc1 -US07566712B2,6,COC(=O)CCc1cccc(-c2cc(N3CCN(c4ncccc4C(F)(F)F)CC3)nc(N3CCOCC3)n2)c1>>O=C(O)CCc1cccc(-c2cc(N3CCN(c4ncccc4C(F)(F)F)CC3)nc(N3CCOCC3)n2)c1 -US09115139B2,1,Clc1cncc(Cl)n1.NCC1CC1>>Clc1cncc(NCC2CC2)n1 -US05202437,6,CC(=O)S[C@H]1C[C@@H](CN2CCNC2=O)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1>>O=C1NCCN1C[C@@H]1C[C@H](S)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1 -US20140100231A1,7,COC(=O)c1cc(Br)c(=O)n(Cc2ccc(OC)cc2)n1>>COc1ccc(Cn2nc(CO)cc(Br)c2=O)cc1 -US07465722B2,2,COc1ccccc1-c1ccc(C(=O)O)cc1.c1ccc2c(c1)Cn1cccc1CN2>>COc1ccccc1-c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 -US20130345123A1,2,COC(=O)[C@H](CC[C@H](Cc1ccccc1)C(=O)O)Cc1ccccc1.N[C@H]1CCCCN(c2ccccc2)C1=O>>COC(=O)[C@H](CC[C@H](Cc1ccccc1)C(=O)N[C@@H]1CCCCN(c2ccccc2)C1=O)Cc1ccccc1 -US20090018134A1,3,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3cc(F)cc(F)c3)CCN(Cc3ccccc3)CC2)nc(Cl)n1.O=C(Nc1ccc(B(O)O)cc1)NC1CC1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3cc(F)cc(F)c3)CCN(Cc3ccccc3)CC2)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 -US20110118230A1,3,Clc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCCCC4)cc3)cc12.OB(O)c1cncnc1>>c1ncc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(CN5CCCCC5)cc4)cc23)cn1 -US20070254877A1,7,OC1(C#Cc2ccccc2)CCNCC1>>OC1(/C=C/c2ccccc2)CCNCC1 -US08536168B2,1,COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.COC(=O)c1cnc(Cl)nc1C(F)(F)F>>COC(=O)c1cnc(N2CCN(C(=O)OC(C)(C)C)C[C@H]2C(=O)OC)nc1C(F)(F)F -US20140080816A1,7,O=C1Nc2ccccc2N2CCCCCC12>>c1ccc2c(c1)NCC1CCCCCN21 -US20120071512A1,7,CN1C(=O)C(=O)c2c(Cl)cccc21>>CN1C(=O)Cc2c(Cl)cccc21 -US05519138,6,CCCCc1nc2c(C)cc(NC(=O)C(C)(C)C)cc2n1Cc1ccc(OC(C(=O)OCC)c2ccccc2)cc1>>CCCCc1nc2c(C)cc(NC(=O)C(C)(C)C)cc2n1Cc1ccc(OC(C(=O)O)c2ccccc2)cc1 -US20100152160A1,6,CCOc1cc2c(cc1Cl)N(C(=O)OC(C)(C)C)CC(C(=O)N1CCC(C#N)(Cc3ccc(F)cc3)CC1)O2>>CCOc1cc2c(cc1Cl)NCC(C(=O)N1CCC(C#N)(Cc3ccc(F)cc3)CC1)O2 -US20140275070A1,9,COc1c(C)ccc2[nH]c(C(N)=O)cc12>>COc1c(C)ccc2[nH]c(C#N)cc12 -US20150266867A1,6,CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)N[C@@H]2C(=O)N[C@@H]2CNCCNC(=O)OCC2c3ccccc3-c3ccccc32)cs1>>CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)N[C@@H]2C(=O)N[C@@H]2CNCCN)cs1 -US06046213,7,Cc1cc(C(=O)C(C)N2CCC(O)(c3ccc(F)cc3)CC2)ccc1O[Si](C(C)C)(C(C)C)C(C)C>>Cc1cc([C@@H](O)[C@@H](C)N2CCC(O)(c3ccc(F)cc3)CC2)ccc1O[Si](C(C)C)(C(C)C)C(C)C -US06407094B1,3,CC(C)(C)OC(=O)COc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1I.OB(O)c1ccc(F)cc1>>CC(C)(C)OC(=O)COc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1-c1ccc(F)cc1 -US20150218150A1,2,CN1Cc2cc(-c3ccc(-c4cncc(N)c4)s3)ccc2C1=O.O=S(=O)(Cl)c1cccc(Cl)c1F>>CN1Cc2cc(-c3ccc(-c4cncc(NS(=O)(=O)c5cccc(Cl)c5F)c4)s3)ccc2C1=O -US20090124607A1,2,C[C@H](N)C(N)=O.Cc1nn(C2CCCC2)c(C)c1S(=O)(=O)Cl>>Cc1nn(C2CCCC2)c(C)c1S(=O)(=O)N[C@@H](C)C(N)=O -US20030236412A1,4,CCOC(=O)C(C(C)=O)C(C)=O.NNC1CCCCC1>>CCOC(=O)c1c(C)nn(C2CCCCC2)c1C -US20030144326A1,1,CCCCS(=O)(=O)Nc1ccc(N2CCC(=O)CC2)cc1.NC[C@H](O)COc1ccc(O)c(NS(=O)(=O)c2ccccc2)c1>>CCCCS(=O)(=O)Nc1ccc(N2CCC(NC[C@H](O)COc3ccc(O)c(NS(=O)(=O)c4ccccc4)c3)CC2)cc1 -US20120252784A1,1,CCI.O=S1(=O)Cc2cc(Cl)c(Cl)cc2C(c2ccc(F)cc2)=NN1>>CCN1N=C(c2ccc(F)cc2)c2cc(Cl)c(Cl)cc2CS1(=O)=O -US20140171430A1,2,N#Cc1ccccc1C(=O)O.c1ccc2nc(N3CC4CNCC4C3)cnc2c1>>N#Cc1ccccc1C(=O)N1CC2CN(c3cnc4ccccc4n3)CC2C1 -US20060069286A1,2,COC(=O)C(N)Cc1ccc(Cl)c(Cl)c1.O=C(O)c1ccc(I)cc1NS(=O)(=O)c1cccc2nsnc12>>COC(=O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc(I)cc1NS(=O)(=O)c1cccc2nsnc12 -US20110269778A1,1,COc1ccc(N)cc1.O=[N+]([O-])c1c(Cl)ncnc1Cl>>COc1ccc(Nc2ncnc(Cl)c2[N+](=O)[O-])cc1 -US06380387B1,6,CCn1c(C)c(-c2ccc(C[C@H](NC(=O)c3c(C)cccc3Cl)C(=O)OC)cc2)c(=O)n(CC)c1=O>>CCn1c(C)c(-c2ccc(C[C@H](NC(=O)c3c(C)cccc3Cl)C(=O)O)cc2)c(=O)n(CC)c1=O -US20100261727A1,1,CO.Clc1ccc(Br)cn1>>COc1ccc(Br)cn1 -US05015659,9,NO.O=C(O)CNC(=O)C(=O)c1cccs1>>O=C(O)CNC(=O)C(=NO)c1cccs1 -US05789402,1,ClCCCOc1cccc2[nH]ccc12.Clc1ccc2[nH]cc(C3=CCNCC3)c2c1>>Clc1ccc2[nH]cc(C3=CCN(CCCOc4cccc5[nH]ccc45)CC3)c2c1 -US07981883B2,2,CC(C)(C)C1CCC2(CC1)CC(C(=O)O)=NO2.CC(C)(C)c1ccc(N)cc1>>CC(C)(C)c1ccc(NC(=O)C2=NOC3(CCC(C(C)(C)C)CC3)C2)cc1 -US05807860,1,CCCCCCCN.COc1cccc(C=O)c1OCc1ccccc1>>CCCCCCCNCc1cccc(OC)c1OCc1ccccc1 -US04069342,8,CC(=O)OO.CCSc1c(Cl)c(Cl)c(Cl)c(C#N)c1C#N>>CCS(=O)c1c(Cl)c(Cl)c(Cl)c(C#N)c1C#N -US04234735,6,N=C(N)Nc1nc(CCCCN2C(=O)c3ccccc3C2=O)c[nH]1>>N=C(N)Nc1nc(CCCCN)c[nH]1 -US04980470,1,C=O.COc1c(N2CCNCC2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>COc1c(N2CCN(C)CC2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US20140357664A1,8,C[C@H]1c2cccc(CCO)c2C[C@H](CO[Si](C)(C)C(C)(C)C)N1C(=O)Cc1c(Cl)cccc1Cl>>C[C@H]1c2cccc(CC=O)c2C[C@H](CO[Si](C)(C)C(C)(C)C)N1C(=O)Cc1c(Cl)cccc1Cl -US20060111351A1,2,Cc1ccc(C(=O)c2cc(Cl)ccc2N)cn1.Cc1ncc(-c2ccc(S(=O)(=O)Cl)cc2)o1>>Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(-c3cnc(C)o3)cc2)cn1 -US20150210697A1,6,COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCC5C(CCN5C(=O)OC(C)(C)C)C4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCC5NCCC5C4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1 -US20130158002A1,3,CN1c2cc(B3OC(C)(C)C(C)(C)O3)ccc2N(CC2CC2(F)F)S1(=O)=O.OCc1cccc(Br)n1>>CN1c2cc(-c3cccc(CO)n3)ccc2N(CC2CC2(F)F)S1(=O)=O -US20140249137A1,3,CC1(C)OB(c2ccc(CC#N)cc2)OC1(C)C.Clc1nccc(OCc2ccccc2)n1>>N#CCc1ccc(-c2nccc(OCc3ccccc3)n2)cc1 -US05981535,1,C1CCNCC1.O=c1c2[nH]c(Br)nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1>>O=c1c2[nH]c(N3CCCCC3)nc2n(CC2CCCCC2)c(=O)n1CC1CCCCC1 -US20140243302A1,1,COc1ccc2nnc(C#N)c(/C=C/C34CCC(N)(CC3)CO4)c2n1.O=Cc1ccc2c(n1)NC(=O)CO2>>COc1ccc2nnc(C#N)c(/C=C/C34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 -US06586441B2,3,Nc1ncc(I)c(-c2ccccc2)n1.OB(O)c1ccccc1>>Nc1ncc(-c2ccccc2)c(-c2ccccc2)n1 -US06303637B1,2,COc1ccccc1C(=O)NCC1(c2ccccc2)CCNCC1.O=C(Cl)c1ccccc1>>COc1ccccc1C(=O)NCC1(c2ccccc2)CCN(C(=O)c2ccccc2)CC1 -US04957916,1,C1CNCCN1.Cc1cccc2c(Cl)noc12>>Cc1cccc2c(N3CCNCC3)noc12 -US20050288317A1,2,O=C(C1CCCNC1)N1CCC(c2cccnc2)C1.O=S(=O)(Cl)c1ccccc1>>O=C(C1CCCN(S(=O)(=O)c2ccccc2)C1)N1CCC(c2cccnc2)C1 -US20090197877A1,6,O=C(NC(=S)Nc1cc(Br)cc(I)c1)c1ccccc1>>NC(=S)Nc1cc(Br)cc(I)c1 -US20120135964A1,6,CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCC(=O)N1CCN(C(=O)OC(C)(C)C)CC1)COC(=O)Nc1cc(-c2cccc(F)c2)on1>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCC(=O)N1CCNCC1)COC(=O)Nc1cc(-c2cccc(F)c2)on1 -US07468457B2,1,CC(C)CBr.COC(=O)c1cc(-c2ccc(C)cc2)c(O)c(C(C)(C)C)c1>>COC(=O)c1cc(-c2ccc(C)cc2)c(OCC(C)C)c(C(C)(C)C)c1 -US08133909B2,1,CCI.Cc1n[nH]c2ccc([N+](=O)[O-])cc12>>CCn1nc(C)c2cc([N+](=O)[O-])ccc21 -US04731370,7,CCOC(=O)/C=C/c1ccc(Cn2ccnc2)cc1>>OC/C=C/c1ccc(Cn2ccnc2)cc1 -US05250527,8,COc1ccc2[nH]c(SCc3nccc(N4CCOCC4)c3Cl)nc2c1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2[nH]c(S(=O)Cc3nccc(N4CCOCC4)c3Cl)nc2c1 -US20140112945A1,2,CN(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)O.COc1ccc(C2=NN(C3CCNCC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](CN(C)C)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US20130281432A1,1,CC1(C)OB(c2cccc(N)c2CO[Si](C)(C)C(C)(C)C)OC1(C)C.COC(=O)c1sc(C(C)(C)C)nc1CBr>>COC(=O)c1sc(C(C)(C)C)nc1CNc1cccc(B2OC(C)(C)C(C)(C)O2)c1CO[Si](C)(C)C(C)(C)C -US20030073836A1,2,CC(C)n1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O.Cc1ccc(-c2ccc(CN)cc2)cc1>>Cc1ccc(-c2ccc(CNC(=O)c3cc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)cn3C(C)C)cc2)cc1 -US20100063067A1,6,COc1cc(N2CCC3(CC2)OCCO3)ccc1Cl>>COc1cc(N2CCC(=O)CC2)ccc1Cl -US20090054399A1,6,CC(=O)OCCN1CCCCn2c(c3c(c(O)c2=O)C(=O)N(Cc2ccc(F)c(Cl)c2)CC3)C1=O>>O=C1c2c(c3n(c(=O)c2O)CCCCN(CCO)C3=O)CCN1Cc1ccc(F)c(Cl)c1 -US20100324284A1,1,COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4)cn2)cc1.Clc1cc(I)ccn1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4c3ccnc(Cl)c3)cn2)cc1 -US07618978B2,6,CCCN(C)C(=O)c1cc(C(=O)OCc2ccccc2)cc(-c2ccncc2)c1>>CCCN(C)C(=O)c1cc(C(=O)O)cc(-c2ccncc2)c1 -US05925253,4,C=CCCCOC(=O)C(=C)C.O=C(OO)c1cccc(Cl)c1>>C=C(C)C(=O)OCCCC1CO1 -US20120171245A1,6,COC(=O)N[C@@H]1CCC[C@H](NC(=O)OCc2ccccc2)C1>>COC(=O)N[C@@H]1CCC[C@H](N)C1 -US07501406B2,3,C=CC[C@@H](NC(=O)OC(C)(C)C)C(=O)N(CC=C)Cc1ccc(OC)cc1OC>>COc1ccc(CN2CC=CC[C@@H](NC(=O)OC(C)(C)C)C2=O)c(OC)c1 -US20070072896A1,7,Cn1cc(-c2c[nH]c3ncc(C(=O)N4CCc5ccccc54)cc23)cn1>>Cn1cc(-c2c[nH]c3ncc(CN4CCc5ccccc54)cc23)cn1 -US04321372,6,CCOC(=O)C(=O)Nc1ncc(C)s1>>Cc1cnc(NC(=O)C(=O)O)s1 -US20100099673A1,3,O=C1CCN(C(=O)OCc2ccccc2)[C@H]2CCCC[C@@H]12.[Mg+]c1ccccc1>>O=C(OCc1ccccc1)N1CCC(O)(c2ccccc2)[C@@H]2CCCC[C@@H]21 -US08415345B2,9,C=CCOC(=O)Nc1cccc(-c2nc(C(C)(C)C)sc2-c2ccnc(Cl)n2)c1F.N>>C=CCOC(=O)Nc1cccc(-c2nc(C(C)(C)C)sc2-c2ccnc(N)n2)c1F -US06407096B1,6,COC(=O)COc1cccc2c1OCC2CCO>>O=C(O)COc1cccc2c1OCC2CCO -US20150284321A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccccc1NC(=O)Nc1ccc(Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2ccccc2NC(=O)Nc2ccc(Cl)cc2)cc1 -US08273747B2,2,COc1ccc(B(O)O)cc1CNC1CCC(N(C)C(=O)OC(C)(C)C)CC1.O=C(Cl)c1sc2c(F)ccc(F)c2c1Cl>>COc1ccc(B(O)O)cc1CN(C(=O)c1sc2c(F)ccc(F)c2c1Cl)C1CCC(N(C)C(=O)OC(C)(C)C)CC1 -US20130045986A1,2,CS(=O)(=O)c1ccc(C(=O)Cl)c(F)c1.Nc1cc(Br)ccc1Br>>CS(=O)(=O)c1ccc(C(=O)Nc2cc(Br)ccc2Br)c(F)c1 -US07439232B2,6,COCOc1cnccc1C(O)c1ccc(C(=O)OC)cc1>>COC(=O)c1ccc(C(O)c2ccncc2O)cc1 -US09096600B2,1,Brc1ncnc2[nH]cnc12.COc1c(C(C)N)cc(Cl)c(C)c1-c1ccc(C(=O)N2CC(C#N)C2)c(F)c1>>COc1c(C(C)Nc2ncnc3[nH]cnc23)cc(Cl)c(C)c1-c1ccc(C(=O)N2CC(C#N)C2)c(F)c1 -US08907094B2,2,COc1c(N)cc(C(C)(C)C)cc1NS(C)(=O)=O.O=C(Cl)OCC(Cl)(Cl)Cl>>COc1c(NC(=O)OCC(Cl)(Cl)Cl)cc(C(C)(C)C)cc1NS(C)(=O)=O -US20100081650A1,3,C=CC(=O)OCCCC.C=CC=COC(C)=O>>CCCCOC(=O)C1CCC=CC1OC(C)=O -US20100256097A1,1,CC(C)(O)c1ccc(-c2cc(C(N)=O)c(N)s2)c(F)c1.COCC(c1cccc(Br)n1)N1CCOCC1>>COCC(c1cccc(Nc2sc(-c3ccc(C(C)(C)O)cc3F)cc2C(N)=O)n1)N1CCOCC1 -US07781593B2,3,COC(=O)c1cnc(Cl)c(Br)c1.OB(O)c1ccc(Cl)cc1>>COC(=O)c1cnc(Cl)c(-c2ccc(Cl)cc2)c1 -US20120214769A1,6,COC(=O)c1ccc(CC(C(=O)N(c2ccccc2)c2ccc3cccc-3o2)c2ccc(C3=CCCCC3)cc2)cc1>>O=C(O)c1ccc(CC(C(=O)N(c2ccccc2)c2ccc3cccc-3o2)c2ccc(C3=CCCCC3)cc2)cc1 -US20120077811A1,1,COc1ccc(CN)cc1.Fc1cc2c(Nc3ccc(F)c(Br)c3)ncnc2cn1>>COc1ccc(CNc2cc3c(Nc4ccc(F)c(Br)c4)ncnc3cn2)cc1 -US04062862,2,CC(=O)Br.O=C1NCC(Cc2ccccc2O)O1>>CC(=O)Oc1ccccc1CC1CNC(=O)O1 -US05519138,9,BrC(Br)(Br)Br.CCOC(=O)C(Oc1ccc(CO)cc1)c1ccccc1>>CCOC(=O)C(Oc1ccc(CBr)cc1)c1ccccc1 -US20070155716A1,1,Fc1ccccc1-c1nc(Cl)c2ccsc2n1.Nc1ccncc1>>Fc1ccccc1-c1nc(Nc2ccncc2)c2ccsc2n1 -US07378412B2,2,O=C(Cl)CCCBr.O=C(O)c1cc(O)ccc1O>>O=C(CCCBr)Oc1ccc(O)c(C(=O)O)c1 -US20100124550A1,8,COCCCOc1cc(C(O)CC(C)C)ccc1OC>>COCCCOc1cc(C(=O)CC(C)C)ccc1OC -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(N)CC1.O=C=NC1CCCC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(NC(=O)NC2CCCC2)CC1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](C2CCC2)NC1=O.O=C(O)c1cc(-c2ccc(F)cc2)on1>>CC(C)C[C@H]1C(=O)N[C@@H](C2CCC2)CN1C(=O)c1cc(-c2ccc(F)cc2)on1 -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)Nc2ncc(C(F)(F)F)cc2Cl)cc1.Fc1ccc(CBr)cc1F>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(F)c(F)c2)c2ncc(C(F)(F)F)cc2Cl)cc1 -US20120101136A1,1,CCOC(=O)CCCBr.CCc1cc(O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1>>CCOC(=O)CCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c(CC)c1 -US20150166564A1,1,COCCN.C[Si](C)(C)CCl>>COCCNC[Si](C)(C)C -US05635510,2,COc1cc(C(=O)Cl)cc(OC)c1OC.Clc1ccc(C2(CCCOC3CCCCO3)CCNC2)cc1Cl>>COc1cc(C(=O)N2CCC(CCCOC3CCCCO3)(c3ccc(Cl)c(Cl)c3)C2)cc(OC)c1OC -US20060069013A1,6,CCOC(=O)CCCOc1ccc(C=O)cc1>>O=Cc1ccc(OCCCC(=O)O)cc1 -US20150239866A1,4,C#Cc1cc(C)cc(Nc2cc(C(F)F)ccn2)n1.COc1ccc(CN2CC(CN=[N+]=[N-])CC2=O)c(OC)c1>>COc1ccc(CN2CC(Cn3cc(-c4cc(C)cc(Nc5cc(C(F)F)ccn5)n4)nn3)CC2=O)c(OC)c1 -US20090318412A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Cl)cc2F)C(CO)C1>>CC(C)(C)OC(=O)N1CCN2C(=O)c3ccc(Cl)cc3OCC2C1 -US07745438B2,3,CC(C)(C)OC(=O)N1[C@H](C=O)COC1(C)C.O=[N+]([O-])CCc1cc(F)cc(F)c1>>CC(C)(C)OC(=O)N1[C@@H]([C@@H](O)[C@H](Cc2cc(F)cc(F)c2)[N+](=O)[O-])COC1(C)C -US08513239B2,2,CC(C)c1ccc(N)cc1.CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)O)CC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC(CC(=O)Nc2ccc(C(C)C)cc2)CC1 -US20090270359A1,4,CC(=O)CBr.Cc1nn(Cc2ccc(C(N)=S)cc2)c(C)c1-c1ccc(C#N)c(Cl)c1>>Cc1csc(-c2ccc(Cn3nc(C)c(-c4ccc(C#N)c(Cl)c4)c3C)cc2)n1 -US08598174B2,6,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3cc(-c4ccc(F)c(NC(=O)c5cc6c(s5)CCCC6)c4)n[nH]c3=O)nc2)C(=O)C1>>O=C(Nc1cc(-c2cc(Nc3ccc(N4CCNCC4=O)cn3)c(=O)[nH]n2)ccc1F)c1cc2c(s1)CCCC2 -US20130137679A1,6,CC(C)(C)OC(=O)N1CCCN(c2cccc(Cl)c2Cl)CC1>>Clc1cccc(N2CCCNCC2)c1Cl -US20020193367A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(OCC(F)(F)F)c(I)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(I)cc1[N+](=O)[O-] -US08202866B2,6,CCOC(=O)C(CCO[Si](C)(C)C(C)(C)C)c1ccc(/C=C/C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)/C=C/c1ccc(C(CCO[Si](C)(C)C(C)(C)C)C(=O)O)cc1 -US05138058,1,C1CNCCN1.Cc1nccc(Cl)n1>>Cc1nccc(N2CCNCC2)n1 -US04590273,1,CN1CCNCC1.Clc1cc2ccccc2cn1>>CN1CCN(c2cc3ccccc3cn2)CC1 -US04940710,1,CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21.c1ccc(OCC2CNCCN2)cc1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(COc4ccccc4)C3)cc21 -US09084794B2,7,O=C(O)Cc1c(F)cc(Br)cc1F>>OCCc1c(F)cc(Br)cc1F -US20130059836A1,6,CNc1ncc2c(-c3ccc(C)cc3)nn(CC3CCC(NC(=O)OC(C)(C)C)CC3)c2n1>>CNc1ncc2c(-c3ccc(C)cc3)nn(CC3CCC(N)CC3)c2n1 -US20060014790A1,2,C[Si](C)(C)CCO.O=C1CCCC(C(=O)O)C1>>C[Si](C)(C)CCOC(=O)C1CCCC(=O)C1 -US20150090921A1,7,CCCCC=C(C=O)CCC>>CCCCCC(C=O)CCC -US05994378,7,CC(C)(C)c1csc(-c2cc3cc(C(=O)n4cc(CC(=O)OCc5ccccc5)c5cc([N+](=O)[O-])ccc54)ccc3o2)n1>>CC(C)(C)c1csc(-c2cc3cc(C(=O)n4cc(CC(=O)OCc5ccccc5)c5cc(N)ccc54)ccc3o2)n1 -US08501946B2,2,Cc1c(F)ccc(C(=O)Cl)c1Cl.O=C1CNCCN1>>Cc1c(F)ccc(C(=O)N2CCNC(=O)C2)c1Cl -US04342870,1,Cc1ccn2c(=O)c(CCCl)c(C)nc2c1.c1ccc2c(C3CCNCC3)c[nH]c2c1>>Cc1ccn2c(=O)c(CCN3CCC(c4c[nH]c5ccccc45)CC3)c(C)nc2c1 -US20140378487A1,1,COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.OCc1cnc(Oc2ccc(Cl)c(C(F)(F)F)c2)c(F)c1>>COc1ccc2c(c1)CCn1c-2cc(OCc2cnc(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O -US07427683B2,2,N#Cc1ccc(C(=O)Cl)o1.Nc1ccccc1N1CCC(F)(F)CC1>>N#Cc1ccc(C(=O)Nc2ccccc2N2CCC(F)(F)CC2)o1 -US07951824B2,2,CCOC(=O)c1cc(-c2cncc(F)c2)cc(C)n1.N#CCc1csc(N)n1>>Cc1cc(-c2cncc(F)c2)cc(C(=O)Nc2nc(CC#N)cs2)n1 -US20060229312A1,2,COCC(=O)Cl.Cc1ccc2c(N3CCN(CCc4cccc(N)c4)CC3)cccc2n1>>COCC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 -US20030109527A1,2,CCN.O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)Cl)c1Cl>>CCNS(=O)(=O)c1c(Cl)ccc([N+](=O)[O-])c1Cl -US20070244130A1,1,COC(=O)COc1ccc(O)cc1C.FC(F)(F)Oc1ccc(-c2oc(CBr)nc2Br)cc1>>COC(=O)COc1ccc(OCc2nc(Br)c(-c3ccc(OC(F)(F)F)cc3)o2)cc1C -US07186716B2,2,NCCN1CCOCC1.O=C(O)c1ccc(C(=O)c2cc([N+](=O)[O-])ccc2Cl)[nH]1>>O=C(NCCN1CCOCC1)c1ccc(C(=O)c2cc([N+](=O)[O-])ccc2Cl)[nH]1 -US07919506B2,9,BrC(Br)(Br)Br.COC(c1ccc(C(F)(F)F)cc1CO)C1CCCC1>>CO[C@H](c1ccc(C(F)(F)F)cc1CBr)C1CCCC1 -US05990106,1,CC(C)(C)OC(=O)NC12CCC1CNC2.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>CC(C)(C)OC(=O)NC12CCC1CN(c1c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c1F)C2 -US20150183801A1,3,CC(C)(O)C1CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2Br)C1.OB(O)c1cccnc1>>CC(C)(O)C1CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cccnc2)C1 -US20110034507A1,6,COC(=O)c1cccc(Cn2ccc3cc(OCc4c(COc5c(Cl)cc(F)cc5Cl)noc4C(C)C)ccc32)c1>>CC(C)c1onc(COc2c(Cl)cc(F)cc2Cl)c1COc1ccc2c(ccn2Cc2cccc(C(=O)O)c2)c1 -US20040220191A1,1,CCCCBr.CN(C)C1CCN(c2ccc(NC(=O)c3ccc(O)nc3)cc2)C1>>CCCCOc1ccc(C(=O)Nc2ccc(N3CCC(N(C)C)C3)cc2)cn1 -US20060004084A1,3,O=C1Cc2cc(Cl)ccc2N1.O=C1OCc2cc(OCCN3CCOCC3)ccc21>>O=C1Nc2ccc(Cl)cc2C1=C1OCc2cc(OCCN3CCOCC3)ccc21 -US20080306153A1,1,CCCCCCCCCCCCCCCC(=O)OCC(CN(C)C)OC(=O)CCCCCCCCCCCCCCC.OCCCCCCCCCCCCCCCCCCCCBr>>CCCCCCCCCCCCCCCC(=O)OCC(C[N+](C)(C)CCCCCCCCCCCCCCCCCCCCO)OC(=O)CCCCCCCCCCCCCCC -US08519135B2,3,CCOc1ccccc1C(=O)N(C)OC.COCN(c1cc(Cl)cnc1Br)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>CCOc1ccccc1C(=O)c1ncc(Cl)cc1N(COC)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 -US20150152131A1,1,BrCc1ccccc1.CO[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@]1(C)O>>CO[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@]1(C)OCc1ccccc1 -US20120316147A1,2,CC(C)CC(N)c1cccnc1.O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1>>CC(C)CC(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)c1cccnc1 -US20040204584A1,2,COc1ccc(C2COCCO2)c2sc(N)nc12.O=C(O)C1CCCCC1>>COc1ccc(C2COCCO2)c2sc(NC(=O)C3CCCCC3)nc12 -US20090192136A1,2,CNS(=O)(=O)c1cc(F)c(F)c(C(=O)O)c1.FC(F)(F)c1ccc(N2CCNCC2)cc1>>CNS(=O)(=O)c1cc(F)c(F)c(C(=O)N2CCN(c3ccc(C(F)(F)F)cc3)CC2)c1 -US05284975,3,CC(=O)N(C)C.O=C(Cc1ccccc1)c1ccccc1>>CN(C)C(=O)CC(O)(Cc1ccccc1)c1ccccc1 -US20070066583A1,6,CCOC(=O)COc1ccc2c(c1)oc(=O)n2CC(=O)N1CCN(c2ccc(Cl)c(OC)c2)CC1>>COc1cc(N2CCN(C(=O)Cn3c(=O)oc4cc(OCC(=O)O)ccc43)CC2)ccc1Cl -US20040102508A1,7,NS(=O)(=O)Cc1ccc([N+](=O)[O-])cc1>>Nc1ccc(CS(N)(=O)=O)cc1 -US20050250822A1,6,Cc1cc(C2(C(F)(F)F)CC(c3ccc(F)cc3)=NO2)ccc1NC(=O)OC(C)(C)C>>Cc1cc(C2(C(F)(F)F)CC(c3ccc(F)cc3)=NO2)ccc1N -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.CC1(C)C(=O)c2ccc(Br)cc2S1(=O)=O>>CC(C)(C)OC(=O)COc1ccc(Cl)cc1C#Cc1ccc2c(c1)S(=O)(=O)C(C)(C)C2=O -US20060142315A1,1,CC(C)(C)OC(=O)c1ccc(CBr)cc1.COc1ccc(O)cc1C=O>>COc1ccc(OCc2ccc(C(=O)OC(C)(C)C)cc2)cc1C=O -US20090069326A1,6,COC(=O)c1ccc(-c2cc(Cl)c(C[C@@H]3CCN([C@@H]4CC[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)CC4)C3=O)c(Cl)c2)cc1>>CC(C)[Si](O[C@@H]1CC[C@@H](N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(C(=O)O)cc4)cc3Cl)C2=O)CC1)(C(C)C)C(C)C -US20100234395A1,2,O=C(Cl)OCc1ccccc1.O=C(O)C1CCNCC1>>O=C(O)C1CCN(C(=O)OCc2ccccc2)CC1 -US20060089375A1,9,CCn1ncc2c(Cl)c(C(=O)O)cnc21.N>>CCn1ncc2c(Cl)c(C(N)=O)cnc21 -US08598357B2,2,N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1.O=C(O)C[C@H]1CCCO1>>O=C(C[C@H]1CCCO1)N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3OCO4)CC2)CC1 -US20060100201A1,7,Cc1ccc(C)n1-c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-]>>Cc1ccc(C)n1-c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N -US08853215B2,1,CC(C)(C)OC(=O)CBr.CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(N3CCNC3=O)cc2)CC1>>CC(C)(C)OC(=O)CN1CCN(c2ccc(C(=O)N3CCN(c4ccccc4C(C)(C)C)CC3)cc2)C1=O -US20110053925A1,1,BrCc1ccc(Br)cc1.Cc1[nH]c2ccccc2c1C1CNCC(=O)C1>>Cc1[nH]c2ccccc2c1C1CC(=O)CN(Cc2ccc(Br)cc2)C1 -US20130231327A1,6,COC(=O)c1ccc2c(c1)[C@H](N(C)S(=O)(=O)c1ccccc1Cl)CC2>>CN([C@@H]1CCc2ccc(C(=O)O)cc21)S(=O)(=O)c1ccccc1Cl -US20110105514A1,6,CCc1cn(CCNC(=O)OC(C)(C)C)cn1>>CCc1cn(CCN)cn1 -US20090124598A1,2,CNCc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1.O=C(Cl)c1cccs1>>CN(Cc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1)C(=O)c1cccs1 -US08927536B2,6,Cc1ccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)cc1>>Cc1ccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)cc1 -US20120316161A1,3,CCCC(C(=O)OC)c1c(C)nc2nc(C(C)C)nn2c1Cl.Cc1ccc(B(O)O)cc1>>CCCC(C(=O)OC)c1c(C)nc2nc(C(C)C)nn2c1-c1ccc(C)cc1 -US20020055643A1,7,COc1cc2c(cc1[N+](=O)[O-])C(=O)CCC2>>COc1cc2c(cc1N)C(=O)CCC2 -US06255333B1,6,Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1C#C[Si](C)(C)C>>C#Cc1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1C -US20130296358A1,2,CCOC(=O)C1(C(CN)c2cccnc2)CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCCC2(C1)C(=O)NCC2c1cccnc1 -US08865029B2,9,CCN(CCO)c1ccc(C2=CC(=O)C(=O)c3ccccc32)cc1.NO>>CCN(CCO)c1ccc(C2=CC(=NO)C(=O)c3ccccc32)cc1 -US04066457,1,C1COCCN1.O=C(O)c1cc([N+](=O)[O-])ccc1Cl>>O=C(O)c1cc([N+](=O)[O-])ccc1N1CCOCC1 -US04695634,2,CC(=O)Cl.O=C1NC(=O)C(c2ccsc2)O1>>CC(=O)N1C(=O)OC(c2ccsc2)C1=O -US20100261719A1,6,C[C@H]1CN(c2c(C=O)cc(C#C[Si](C)(C)C)c(F)c2F)C[C@@H](C)O1>>C#Cc1cc(C=O)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F -US20150284408A1,6,Cc1ccc(CNC2CCN(C(=O)OC(C)(C)C)CC2)cc1C(C)C(F)(F)F>>Cc1ccc(CNC2CCNCC2)cc1C(C)C(F)(F)F -US09090599B2,2,CC(C)c1cc(CN)no1.O=C(O)c1ccc(OCC2CC2)c(-c2ccc(Cl)cc2)n1>>CC(C)c1cc(CNC(=O)c2ccc(OCC3CC3)c(-c3ccc(Cl)cc3)n2)no1 -US20080293782A1,6,COC(=O)CN(c1cc(Oc2ccccc2)ccc1OCc1ccccc1)S(=O)(=O)NC(=O)OC(C)(C)C>>COC(=O)CN(c1cc(Oc2ccccc2)ccc1OCc1ccccc1)S(N)(=O)=O -US20150141400A1,2,CCS(=O)(=O)n1cccc1CN.Nc1ccc(C(F)(F)F)cc1C(=O)O>>CCS(=O)(=O)n1cccc1CNC(=O)c1cc(C(F)(F)F)ccc1N -US20140088094A1,7,O=[N+]([O-])c1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)CCC2>>Nc1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)CCC2 -US20150087626A1,6,COC(=O)c1ccc(C2(NC(=O)[C@H]3C[C@H]4C[C@H]4N3C(=O)OC(C)(C)C)CC2)cc1>>COC(=O)c1ccc(C2(NC(=O)[C@H]3C[C@H]4C[C@H]4N3)CC2)cc1 -US20100120858A1,1,CC(C)(C)OC(=O)N1CCC[C@H](COc2ccc(F)cc2O)C1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H](COc2ccc(F)cc2Oc2ccccc2)C1 -US20090149501A1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCOCC1>>CCOC(=O)C=C1CCOCC1 -US20110124634A1,1,CC(C)CCCBr.COc1ccc(Cc2c[nH]c3c(Cl)nc(N)nc23)cc1OC>>COc1ccc(Cc2cn(CCCC(C)C)c3c(Cl)nc(N)nc23)cc1OC -US20100239576A1,2,CC(C)(C)OC(=O)NCC(=O)O.COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)O)n(-c5ccccc5)c4=O)cc3F)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)OC(=O)CNC(=O)OC(C)(C)C)n(-c5ccccc5)c4=O)cc3F)c2cc1OC -US09000025B2,2,CN(C)CCN.Cc1c(Sc2cccc(C(=O)O)c2)c2ccc(Br)cc2n1Cc1ccccc1>>Cc1c(Sc2cccc(C(=O)NCCN(C)C)c2)c2ccc(Br)cc2n1Cc1ccccc1 -US08143263B2,6,CC(C)(C)[Si](C)(C)OC1CN(C[C@H](Oc2ncnc3c2cnn3-c2ccccc2Cl)C(=O)Nc2ccc(F)cn2)C1>>O=C(Nc1ccc(F)cn1)[C@H](CN1CC(O)C1)Oc1ncnc2c1cnn2-c1ccccc1Cl -US20100022613A1,1,Fc1ccc(CBr)cc1.Sc1cccc(Br)c1>>Fc1ccc(CSc2cccc(Br)c2)cc1 -US20060040917A1,1,C1CCNCC1.CC(C)(C)[Si](C)(C)Oc1cccc(C2COc3cc(O[Si](C)(C)C(C)(C)C)ccc3N(C(=O)c3cccc(OCCCl)c3)C2)c1>>CC(C)(C)[Si](C)(C)Oc1cccc(C2COc3cc(O[Si](C)(C)C(C)(C)C)ccc3N(C(=O)c3cccc(OCCN4CCCCC4)c3)C2)c1 -US20120053180A1,1,O=C(NC1CCC(c2nc(CCl)cs2)CC1)OCc1ccccc1.Oc1ccc(-n2cnnn2)cc1>>O=C(NC1CCC(c2nc(COc3ccc(-n4cnnn4)cc3)cs2)CC1)OCc1ccccc1 -US20070293526A1,6,CN(CC(=O)NCc1cccc2cc(S(=O)(=O)c3ccccc3)ccc12)C(=O)OCc1ccccc1>>CNCC(=O)NCc1cccc2cc(S(=O)(=O)c3ccccc3)ccc12 -US20120225859A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1nc(N)ncc1Br>>COc1nc(N)ncc1B1OC(C)(C)C(C)(C)O1 -US20100120741A1,2,CCOC(=O)Cl.N#Cc1cc(F)c(F)cc1N>>CCOC(=O)Nc1cc(F)c(F)cc1C#N -US20030092694A1,2,CC(=O)OC(C)=O.Nc1ccc2c(c1)OC(CO)CO2>>CC(=O)Nc1ccc2c(c1)OC(CO)CO2 -US04950674,1,COc1cc(OCCCCl)ccc1C(C)=O.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>COc1cc(OCCCN2CCC(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)ccc1C(C)=O -US06583299B1,6,COC(=O)[C@H](CS(=O)(=O)c1ccc(Oc2ccccc2)cc1)NC(C)=O>>CC(=O)N[C@@H](CS(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)O -US06492562B1,3,CCC(=O)n1c(=O)oc2ccccc21.O=Cc1ccccc1>>C[C@@H](C(=O)n1c(=O)oc2ccccc21)[C@H](O)c1ccccc1 -US09079866B2,3,CC(C)S(=O)(=O)c1ncccc1Br.CC1(C)OB(c2ccc(-c3cnc4[nH]ccc4c3)c(F)c2)OC1(C)C>>CC(C)S(=O)(=O)c1ncccc1-c1ccc(-c2cnc3[nH]ccc3c2)c(F)c1 -US20090012063A1,3,CCCCCCc1cccc(-c2nc(I)c(C(=O)N3CCC(N4CCC[C@@H]4CO)CC3)n2C)c1.OB(O)c1cccnc1>>CCCCCCc1cccc(-c2nc(-c3cccnc3)c(C(=O)N3CCC(N4CCC[C@@H]4CO)CC3)n2C)c1 -US07071175B1,6,CCOC(=O)C(C(=O)OCC)C(CC)c1ccc(NC(=O)OC(C)(C)C)nc1>>CCOC(=O)C(C(=O)O)C(CC)c1ccc(NC(=O)OC(C)(C)C)nc1 -US20090215754A1,2,NS(=O)(=O)c1cc(C(=O)O)cc(N2CCCC2)c1Oc1ccccc1.c1ccc(CNCc2ccccc2)cc1>>NS(=O)(=O)c1cc(C(=O)N(Cc2ccccc2)Cc2ccccc2)cc(N2CCCC2)c1Oc1ccccc1 -US20060089371A1,3,COC(=O)[C@H](Cc1ccccc1)Nc1ncnc(Cl)c1C=O.OB(O)c1ccc(OCc2ccccc2)cc1>>COC(=O)[C@H](Cc1ccccc1)Nc1ncnc(-c2ccc(OCc3ccccc3)cc2)c1C=O -US06369070B1,2,CCOC(=O)c1cccc(N)c1.Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Cl>>CCOC(=O)c1cccc(NC(=O)c2c(-c3c(F)cccc3Cl)noc2C)c1 -US07585886B2,6,COC(=O)C(C)(C)COC(=O)N1C[C@H](c2ccccc2)[C@@H](CN(C(=O)OC(C)(C)C)[C@H](C)c2cccc3ccccc23)C1>>COC(=O)C(C)(C)COC(=O)N1C[C@H](c2ccccc2)[C@@H](CN[C@H](C)c2cccc3ccccc23)C1 -US05233089,7,COc1ccc(C(=O)C(O)c2ccc(OC)cc2)cc1>>COc1ccc(C(O)C(O)c2ccc(OC)cc2)cc1 -US05064844,1,CC(=O)C=NO.NNc1c(Cl)cc(C(F)(F)F)cc1Cl>>CC(C=NO)=NNc1c(Cl)cc(C(F)(F)F)cc1Cl -US07423181B2,6,C=CC(C)(C)c1ccc(OC)c(C=O)c1>>C=CC(C)(C)c1ccc(O)c(C=O)c1 -US20150232445A1,6,C[C@H]1CCc2c(ccc(-c3cnn(C4CCN(C(=O)OC(C)(C)C)CC4)c3)c2OC2CCC2)N1C(=O)C1CC1>>C[C@H]1CCc2c(ccc(-c3cnn(C4CCNCC4)c3)c2OC2CCC2)N1C(=O)C1CC1 -US06838478B2,3,CN(C)C=O.COc1cc(Cl)cc(Cl)c1>>COc1cc(Cl)cc(C=O)c1 -US20090062280A1,1,CC(C)(C)C(=O)CBr.COc1ccc2nc(C(C)(C)C)c(=O)[nH]c2c1>>COc1ccc2nc(C(C)(C)C)c(=O)n(CC(=O)C(C)(C)C)c2c1 -US08268827B2,1,O=C1CN(C(=O)OCc2ccccc2)CCCN1.OB(O)C1CC1>>O=C(OCc1ccccc1)N1CCCN(C2CC2)C(=O)C1 -US04596809,6,CC(=O)OC1COc2c(c(=O)n(-c3ccccc3)c3ncccc23)C1>>O=c1c2c(c3cccnc3n1-c1ccccc1)OCC(O)C2 -US05218109,7,COC(=O)C(C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@@]21C>>CC(CO)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@@]21C -US20100069357A1,1,CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CCNC3)cc1.CN(C)C(=O)CCl>>CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CCN(CC(=O)N(C)C)C3)cc1 -US07229987B2,2,CCOC(=O)Nc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1.NCCN1CCCCC1>>O=C(NCCN1CCCCC1)Nc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1 -US06297249B1,3,CC(C)(C)OC(=O)C=C(CCCCCCc1ccc2c(n1)NCCC2)OS(=O)(=O)C(F)(F)F.OB(O)c1ccccc1>>CC(C)(C)OC(=O)C=C(CCCCCCc1ccc2c(n1)NCCC2)c1ccccc1 -US20080085905A1,2,CC(C)(C)COc1nc(C(=O)O)cnc1N1CCOCC1.CC(C)C[C@H](N)CO>>CC(C)C[C@@H](CO)NC(=O)c1cnc(N2CCOCC2)c(OCC(C)(C)C)n1 -US05693594,1,CCOC(=O)c1csc(Br)n1.Oc1cccc(Cl)c1>>CCOC(=O)c1csc(Oc2cccc(Cl)c2)n1 -US08658639B2,1,BrCc1ccccc1.COC(=O)c1cc([N+](=O)[O-])c(O)cc1C>>COC(=O)c1cc([N+](=O)[O-])c(OCc2ccccc2)cc1C -US05068227,5,CCOC(=O)C(F)(F)F.NCCCCCC(=O)O>>O=C(O)CCCCCNC(=O)C(F)(F)F -US06608049B2,1,BrCc1ccccc1.O=Cc1ccc(O)cc1[N+](=O)[O-]>>O=Cc1ccc(OCc2ccccc2)cc1[N+](=O)[O-] -US05401740,7,CN1CCCC(C(=O)NCC2CCCCCCC2)C1>>CN1CCCC(CNCC2CCCCCCC2)C1 -US20150111866A1,3,COC(=O)c1cc(C)c(-c2cnc(OC)c(Br)c2)c(C)c1.CSc1ncc(B2OC(C)(C)C(C)(C)O2)c(CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)n1>>COC(=O)c1cc(C)c(-c2cnc(OC)c(-c3cnc(SC)nc3CN3C(=O)O[C@H](c4cc(C(F)(F)F)cc(C(F)(F)F)c4)[C@@H]3C)c2)c(C)c1 -US06127391,1,CC(C)(C)OC(=O)N[C@H](Cc1csc2ccccc12)C(=O)O.CI>>CN(C(=O)OC(C)(C)C)[C@H](Cc1csc2ccccc12)C(=O)O -US08952149B2,3,CN(C)C=O.C[C@H]1CN(c2c(C3OCCO3)cc(Br)c(F)c2F)C[C@@H](C)O1>>C[C@H]1CN(c2c(C3OCCO3)cc(C=O)c(F)c2F)C[C@@H](C)O1 -US05208247,2,CO.O=C(O)c1ccc(O)c(O)c1>>COC(=O)c1ccc(O)c(O)c1 -US20110009435A1,2,COc1cccc(CNC(=O)c2nc3scc(COC[C@@H]4CC[C@@H](CN)CC4)c3c(=O)[nH]2)c1.CS(=O)(=O)Cl>>COc1cccc(CNC(=O)c2nc3scc(COC[C@@H]4CC[C@@H](CNS(C)(=O)=O)CC4)c3c(=O)[nH]2)c1 -US20090286790A1,1,CCC1CC(=O)CC(Cc2ccccc2)N1C(=O)OC(C)(C)C.NCc1ccccc1>>CCC1CC(NCc2ccccc2)CC(Cc2ccccc2)N1C(=O)OC(C)(C)C -US20060287389A1,7,CC1(C)OCc2cc(C(=O)CN=[N+]=[N-])ccc2O1>>CC1(C)OCc2cc([C@@H](O)CN=[N+]=[N-])ccc2O1 -US20060100218A1,3,CCOc1ccc2ccccc2c1C(=O)n1cc(Br)c2cccnc21.CS(=O)(=O)c1ccc(B(O)O)cc1>>CCOc1ccc2ccccc2c1C(=O)n1cc(-c2ccc(S(C)(=O)=O)cc2)c2cccnc21 -US20100041892A1,2,CC(=O)OC(C)=O.CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC)cc1Oc1ncc(N)cc1C>>CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC)cc1Oc1ncc(NC(C)=O)cc1C -US20070225286A1,1,Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1nccn1-c1cc(Cl)ncn1.Nc1ccc(CCN2CCOCC2)cc1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1nccn1-c1cc(Nc2ccc(CCN3CCOCC3)cc2)ncn1 -US04727067,6,O=C(NCCO)NCc1ccccc1OCc1ccccc1>>O=C(NCCO)NCc1ccccc1O -US20130274244A1,6,COCCOc1ccn2c(C(=O)Nc3cccc4c3cnn4CC3CCCN(C(=O)OC(C)(C)C)C3)cnc2c1>>COCCOc1ccn2c(C(=O)Nc3cccc4c3cnn4CC3CCCNC3)cnc2c1 -US07276608B2,9,O=C1[C@@H](NS(=O)(=O)c2ccccc2)Cc2cc(Br)ccc2N1Cc1ccccc1.[C-]#N>>N#Cc1ccc2c(c1)C[C@H](NS(=O)(=O)c1ccccc1)C(=O)N2Cc1ccccc1 -US20120264735A1,3,CC(C)(O)COc1cnc(-c2cccc(B3OC(C)(C)C(C)(C)O3)c2)nc1.N#Cc1cc(F)cc(-n2ccc(=O)c(CCl)n2)c1>>CC(C)(O)COc1cnc(-c2cccc(Cc3nn(-c4cc(F)cc(C#N)c4)ccc3=O)c2)nc1 -US20130090323A1,3,CCCC[Sn](C#N)(CCCC)CCCC.Cc1c(-c2ccccn2)nc2c(Cl)cccc2c1Nc1cccc(N2CCOCC2)n1>>Cc1c(-c2ccccn2)nc2c(C#N)cccc2c1Nc1cccc(N2CCOCC2)n1 -US06514996B2,2,COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c1OCC2CC(=O)O.Nc1ccccc1>>COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c1OCC2CC(=O)Nc1ccccc1 -US20080125429A1,2,CCS(=O)(=O)c1ccc(Oc2ccc(N)c(C(=O)OC)c2)cc1.O=C(O)c1ccccn1>>CCS(=O)(=O)c1ccc(Oc2ccc(NC(=O)c3ccccn3)c(C(=O)OC)c2)cc1 -US20100179211A1,6,CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)c(Cl)c2)C1>>OC1(c2ccc(Cl)c(Cl)c2)CCNC1 -US20120142927A1,1,O=C(C1CC1)C(Br)c1ccccc1F.O=C1CC2=C(CCNC2)S1>>O=C1CC2=C(CCN(C(C(=O)C3CC3)c3ccccc3F)C2)S1 -US20080255086A1,6,CC(C)(C)OC(=O)c1c(NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)sc2c1CCCC2>>O=C(Cn1nc(C(F)(F)F)c2c1CCCC2)Nc1sc2c(c1C(=O)O)CCCC2 -US20140155389A1,7,CCOc1cc(C(=O)N2CCCC2)ccc1N>>CCOc1cc(CN2CCCC2)ccc1N -US20120077839A1,1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.COc1cc2c(cc1OC)[C@H]1C[C@@H](O)[C@H](CC(C)C)CN1CC2>>COc1cc2c(cc1OC)[C@H]1C[C@@H](OC(=O)C(NC(=O)OCc3ccccc3)C(C)C)[C@H](CC(C)C)CN1CC2 -US20110183976A1,6,CCOC(=O)Cc1ccc(OC)cc1>>COc1ccc(CC(=O)O)cc1 -US06114532,7,Cn1c(Cc2ccc(C#N)cc2)nc2cc([N+](=O)[O-])ccc21>>Cn1c(Cc2ccc(C#N)cc2)nc2cc(N)ccc21 -US20090221555A1,1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.CCN1C(=O)CCCc2cc(N)c(OC)cc21>>CCN1C(=O)CCCc2cc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)c(OC)cc21 -US20150232465A1,2,C[C@H]1CNc2cc(Br)ccc2N1C(=O)C(F)(F)F.O=C(Cl)C1CC1>>C[C@H]1CN(C(=O)C2CC2)c2cc(Br)ccc2N1C(=O)C(F)(F)F -US04800212,7,CC1(C)CC(=O)c2cc(Br)ccc2C1>>CC1(C)Cc2ccc(Br)cc2C(O)C1 -US06605620B1,1,CCOc1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1.COc1cc(-c2cncc(CCl)c2)cc(OC)c1OC>>CCOc1ccc(N(Cc2cncc(-c3cc(OC)c(OC)c(OC)c3)c2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US08344029B2,7,O=C(NCCO)/C(=C/c1ccc(OC(F)(F)F)cc1)NC(=O)c1ccc(OCC(F)F)cc1>>O=C(NC(Cc1ccc(OC(F)(F)F)cc1)C(=O)NCCO)c1ccc(OCC(F)F)cc1 -US20050131018A1,6,COC(=O)c1cc2c(OC)cccc2o1>>COc1cccc2oc(C(=O)O)cc12 -US07812076B2,1,Cc1ccc(N2C(=O)c3cccc4c(N)ccc(c34)C2=O)c(C)c1.Cn1c(=O)cc2c3c(c(Br)ccc31)C(=O)c1ccccc1-2>>Cc1ccc(N2C(=O)c3cccc4c(Nc5ccc6c7c(cc(=O)n6C)-c6ccccc6C(=O)c57)ccc(c34)C2=O)c(C)c1 -US07041691B1,4,C[Si](C)(C)N=[N+]=[N-].N#Cc1ccc2sc(Sc3c(Cl)cc(NS(=O)(=O)c4ccc(Cl)cc4Cl)cc3Cl)nc2c1>>O=S(=O)(Nc1cc(Cl)c(Sc2nc3cc(-c4nnn[nH]4)ccc3s2)c(Cl)c1)c1ccc(Cl)cc1Cl -US20150182528A1,3,COC(=O)c1c(O)c2ccc(Br)cc2sc1=O.OB(O)c1ccccc1>>COC(=O)c1c(O)c2ccc(-c3ccccc3)cc2sc1=O -US20140200225A1,2,CC(C)(C)OC(=O)NCCC1CCNCC1.N#Cc1ccc(Oc2ccc(C(=O)O)c(Oc3ccc(F)cc3)n2)cc1>>CC(C)(C)OC(=O)NCCC1CCN(C(=O)c2ccc(Oc3ccc(C#N)cc3)nc2Oc2ccc(F)cc2)CC1 -US20150023913A1,6,COC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)C>>CN(C(=O)OC(C)(C)C)[C@H](C(=O)O)C(C)(C)C -US20120149721A1,2,CC(=O)Cl.COc1ccc(-c2ncnc3c(C(=O)NC4CCNCC4)c(C)[nH]c23)c(OCC2CC2)c1>>COc1ccc(-c2ncnc3c(C(=O)NC4CCN(C(C)=O)CC4)c(C)[nH]c23)c(OCC2CC2)c1 -US05728701,6,COC(=O)C(CCOc1ccc(N2CCN(c3ccncc3)CC2)cc1)NC(=O)OC(C)(C)C>>COC(=O)C(N)CCOc1ccc(N2CCN(c3ccncc3)CC2)cc1 -US06084130,1,CCCBr.CCCN(CCC)C1Cc2cc3c(cc2C1)C(=O)NC3=O>>CCCN1C(=O)c2cc3c(cc2C1=O)CC(N(CCC)CCC)C3 -US20080051430A1,3,CCC(=O)Cl.Cc1ccc(O)cc1Cl>>CCC(=O)c1cc(C)c(Cl)cc1O -US20100173824A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#CCc1c[nH]c2cc(OCc3ccccc3)ccc12>>CC(C)(C)OC(=O)n1cc(CC#N)c2ccc(OCc3ccccc3)cc21 -US06162821,6,CCOC(=O)c1cnn(C)c1N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)c2c(C(=O)O)cnn2C)cc1 -US06121270,1,C=CCCCCCCCCCCCCCCCCl.Cn1cnc2c1c(=O)[nH]c(=O)n2C>>C=CCCCCCCCCCCCCCCCn1c(=O)c2c(ncn2C)n(C)c1=O -US06960688B2,1,CC(=O)Nc1ccc(S)cc1.Nc1cc(Cl)ccc1[N+](=O)[O-]>>CC(=O)Nc1ccc(Sc2ccc([N+](=O)[O-])c(N)c2)cc1 -US20070254881A1,2,C1COCCN1.COc1ccc(-n2nc(C(=O)O)cc2-n2ccc(C(N)=O)c2)cn1>>COc1ccc(-n2nc(C(=O)N3CCOCC3)cc2-n2ccc(C(N)=O)c2)cn1 -US20150141400A1,6,C=Cc1cc2c(=O)n(Cc3cc(Cl)ccc3S(=O)(=O)CC)c(=O)[nH]c2c(Cl)c1CN1CCC[C@@H](NC(=O)OC(C)(C)C)C1>>C=Cc1cc2c(=O)n(Cc3cc(Cl)ccc3S(=O)(=O)CC)c(=O)[nH]c2c(Cl)c1CN1CCC[C@@H](N)C1 -US08426429B2,1,COC(OC)c1cc(Cl)ccc1[N+](=O)[O-].N#Cc1cccc(O)c1>>COC(OC)c1cc(Oc2cccc(C#N)c2)ccc1[N+](=O)[O-] -US20090029963A1,2,CCc1nn(-c2cccc(/C=C/c3ccc(Cl)cc3)c2)c(CC)c1C(=O)O.CN1CCC(CN2CCNCC2)CC1>>CCc1nn(-c2cccc(/C=C/c3ccc(Cl)cc3)c2)c(CC)c1C(=O)N1CCN(CC2CCN(C)CC2)CC1 -US20150080367A1,8,FC(F)c1ccncc1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc(C(F)F)cc1 -US20100041892A1,2,CC(C)CCS(N)(=O)=O.CC(C)Oc1cc(/C=C/C(=O)O)n(Cc2ccc(C(F)(F)F)cc2Cl)n1>>CC(C)CCS(=O)(=O)NC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl -US20080176830A1,7,O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1>>FC(F)(F)c1ccc(-c2ccc3c(c2)CCCN3)cc1 -US04072696,6,CCCS(=O)c1ccc(NC(C)=O)c([N+](=O)[O-])c1>>CCCS(=O)c1ccc(N)c([N+](=O)[O-])c1 -US05077305,1,COC(=O)CBr.Oc1cccc(CCc2nc(-c3ccccc3)c(-c3ccccc3)s2)c1>>COC(=O)COc1cccc(CCc2nc(-c3ccccc3)c(-c3ccccc3)s2)c1 -US20110144068A1,7,O=[N+]([O-])c1cccc(-c2nn(CCF)cc2-c2ccncc2)c1>>Nc1cccc(-c2nn(CCF)cc2-c2ccncc2)c1 -US20150152093A1,1,C[C@@H](C(F)F)[C@H]1COC(=O)N1.Fc1ccnc(F)n1>>C[C@@H](C(F)F)[C@H]1COC(=O)N1c1ccnc(F)n1 -US07989469B2,9,Fc1ncc(Cl)c(-n2cccn2)c1F.N>>Nc1ncc(Cl)c(-n2cccn2)c1F -US20120220585A1,3,Cc1cccc2cc(C=O)c(Cl)nc12.Cc1ccccc1B(O)O>>Cc1ccccc1-c1nc2c(C)cccc2cc1C=O -US05648504,1,COC(=O)c1c(F)c(F)c(F)c(F)c1C(=O)O.C[O-]>>COC(=O)c1c(F)c(F)c(OC)c(F)c1C(=O)O -US08247403B2,6,CCCc1cccc2c1OCCN(C(=O)OC(C)(C)C)C2>>CCCc1cccc2c1OCCNC2 -US05342846,1,C[C@H]1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.c1cn(C2CCNCC2)nn1>>C[C@H]1COc2c(N3CCC(n4ccnn4)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 -US04758578,8,COc1ccc(-c2nsc(SN)n2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nsc(S(N)=O)n2)cc1 -US20060135522A1,9,O=C(N1CCC(C2c3ccccc3Oc3cc(Br)ccc32)CC1)C(F)(F)F.[C-]#N>>N#Cc1ccc2c(c1)Oc1ccccc1C2C1CCN(C(=O)C(F)(F)F)CC1 -US04721718,8,O=C(OO)c1cccc(Cl)c1.c1ccc2[nH]c(SCc3cnc4ccccn34)nc2c1>>O=S(Cc1cnc2ccccn12)c1nc2ccccc2[nH]1 -US20100184802A1,2,NC(=O)Cn1ccc2c(N)cccc2c1=O.O=C(O)CC1CCCCCC1>>NC(=O)Cn1ccc2c(NC(=O)CC3CCCCCC3)cccc2c1=O -US20050288339A1,3,CC(C)(C)c1ccc(OCC(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)cc1.O=Cc1ccc(OCc2ccccc2)cc1>>CC(C)(C)c1ccc(O[C@H](C(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)[C@H](O)c2ccc(OCc3ccccc3)cc2)cc1 -US08119676B2,4,CC(C)(C)OC(=O)N1CC(N)C1.ClCCN(CCCl)Cc1ccccc1>>CC(C)(C)OC(=O)N1CC(N2CCN(Cc3ccccc3)CC2)C1 -US20050245588A1,6,CCOC(=O)[C@@H]1[C@H]2CCC3=Cc4c(cnn4-c4ccc(F)cc4)C[C@]3(C)C2=CC[C@H]1C(F)(F)F>>C[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CC[C@H]1C2=CC[C@@H](C(F)(F)F)[C@@H]1C(=O)O -US20060199800A1,7,C[C@@H]1CCC[C@H](C)C(=O)N1>>C[C@@H]1CCC[C@H](C)NC1 -US07326447B2,1,CCCCCc1ccc(Br)c(O)c1F.Cc1ccc(Br)c(C(=O)O)c1F>>CCCCCc1ccc(Br)c(OC(=O)c2c(Br)ccc(C)c2F)c1F -US07435744B2,2,N#Cc1cccc(N)c1.O=C(O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>N#Cc1cccc(NC(=O)C(=O)N2CCC(Cc3ccc(F)cc3)CC2)c1 -US20030119861A1,1,CC(C)Cn1c(CC(C)O)nc2cnc3ccccc3c21.CI>>COC(C)Cc1nc2cnc3ccccc3c2n1CC(C)C -US20130029942A1,1,CNc1ccc(OC)cc1.COc1ccc2nc(Cl)nc(Cl)c2c1>>COc1ccc(N(C)c2nc(Cl)nc3ccc(OC)cc23)cc1 -US20130115194A1,2,COC(=O)N[C@H](C(=O)O)C(C)C.COC(=O)[C@@H]1C[C@@H](O)CN1>>COC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)OC)C(C)C -US20090105416A1,3,Brc1cccnc1.OB(O)c1cccc(Cl)c1>>Clc1cccc(-c2cccnc2)c1 -US07645781B2,9,COC(=O)[C@H]1CN(c2ccc3c(c2)SCC(=S)N3C)C(=O)O1.N>>CN1C(=S)CSc2cc(N3CC(C(N)=O)OC3=O)ccc21 -US20140155389A1,2,COC(=O)Cl.COc1ccc(CCN)cc1>>COC(=O)NCCc1ccc(OC)cc1 -US07531557B2,6,CC(C)(C)OC(=O)N1CCc2cc(Oc3ccc(C(N)=O)cc3)ccc2C1>>NC(=O)c1ccc(Oc2ccc3c(c2)CCNC3)cc1 -US20150239900A1,6,COc1c(-c2ccc(F)cc2F)c(Cl)cc2c(N3CCN(C(=O)OC(C)(C)C)CC3)ncnc12>>COc1c(-c2ccc(F)cc2F)c(Cl)cc2c(N3CCNCC3)ncnc12 -US08580803B2,1,CNC(=O)c1cccc(N)c1.Cc1ccccc1C(=O)c1c[nH]c2ncnc(Cl)c12>>CNC(=O)c1cccc(Nc2ncnc3[nH]cc(C(=O)c4ccccc4C)c23)c1 -US08741932B2,3,O=Cc1cnc2ccc(Br)cn12.OB(O)c1ccc(Cl)nc1>>O=Cc1cnc2ccc(-c3ccc(Cl)nc3)cn12 -US20110190278A1,1,CC(C)N(C(=O)c1cc2c(cc1C(F)(F)F)OC(C)(C)C(=O)N2CCN)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1.CCC(=O)C(F)(F)F>>CCC(NCCN1C(=O)C(C)(C)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc21)C(F)(F)F -US08541448B2,6,CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(NC(=O)CCOCCOCCOCCN3C(=O)c4ccccc4C3=O)c2)C1>>CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(NC(=O)CCOCCOCCOCCN)c2)C1 -US20120035164A1,1,C1CCNC1.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(C(C)=O)c4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc([C@H](C)N5CCCC5)c4)cc23)CC1 -US20140142085A1,6,CCOC(=O)Cn1nc(C(F)(F)F)c2c1CCC2(F)F>>O=C(O)Cn1nc(C(F)(F)F)c2c1CCC2(F)F -US08946216B2,3,O=[N+]([O-])c1ccc2c(c1)c(Br)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1.OB(O)c1ccncc1>>O=[N+]([O-])c1ccc2c(c1)c(-c1ccncc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US07968570B2,1,C[O-].O=C1c2c(I)cc(F)cc2CN1Cc1ccc(OC(F)(F)F)cc1>>COc1cc(I)c2c(c1)CN(Cc1ccc(OC(F)(F)F)cc1)C2=O -US04243672,7,O=C(c1ccc[nH]1)C1CCCCC1>>c1c[nH]c(CC2CCCCC2)c1 -US05424443,4,Nc1c(F)cc(Cl)c2nc(Cl)sc12.O=C1OC(=O)C2=C1CCCC2>>O=C1C2=C(CCCC2)C(=O)N1c1c(F)cc(Cl)c2nc(Cl)sc12 -US20070043036A1,6,Cc1c(OCC(=O)OC(C)(C)C)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1c(OCC(=O)O)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1 -US20030160212A1,1,CCCCCCBr.CCCCCCOc1c(F)ccc(F)c1O>>CCCCCCOc1c(F)ccc(F)c1OCCCCCC -US20110065702A1,3,COc1cc2c(cc1OC)NC(=O)C2.O=Cc1ccc2cn[nH]c2c1>>COc1cc2c(cc1OC)/C(=C\c1ccc3cn[nH]c3c1)C(=O)N2 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C2CC2)nn1C1CCC1>>O=C(O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C2CC2)nn1C1CCC1 -US09079878B2,1,O=C(CBr)c1ccc(C(F)(F)F)cc1.O=C(O)CC1(NC(=O)OCc2ccccc2)COC1>>O=C(CC1(NC(=O)OCc2ccccc2)COC1)OCC(=O)c1ccc(C(F)(F)F)cc1 -US06756373B1,7,CCOc1ncc([N+](=O)[O-])cc1-c1nc2c(Br)n(C)nc2c(=O)[nH]1>>CCOc1ncc(N)cc1-c1nc2c(Br)n(C)nc2c(=O)[nH]1 -US20070027163A1,1,COc1ccccc1N1CCN(C(=O)c2c[nH]c3cc(Cl)ccc23)CC1.O=C(O)CBr>>COc1ccccc1N1CCN(C(=O)c2cn(CC(=O)O)c3cc(Cl)ccc23)CC1 -US20050209274A1,1,CN(C(=O)c1cc(=O)c2ccc(F)cc2o1)C1CCNCC1.O=Cc1ccc2c(c1)OCO2>>CN(C(=O)c1cc(=O)c2ccc(F)cc2o1)C1CCN(Cc2ccc3c(c2)OCO3)CC1 -US20150252067A1,2,O=C(Cl)c1ccccc1.OCCc1ccc(Br)cc1>>O=C(OCCc1ccc(Br)cc1)c1ccccc1 -US05342841,7,Nc1c(N=O)c(=O)n(C2CC2)c(=O)n1C1CC1>>Nc1c(N)n(C2CC2)c(=O)n(C2CC2)c1=O -US20090270417A1,9,COCCCOc1cc(O[C@@H](CBr)C(C)C)ccc1OC.[C-]#N>>COCCCOc1cc(O[C@@H](CC#N)C(C)C)ccc1OC -US07671063B2,1,COc1cc(Nc2nccc(Cl)n2)cc(OC)c1OC.Nc1ccc2c(c1S(N)(=O)=O)OCCO2>>COc1cc(Nc2nccc(Nc3ccc4c(c3S(N)(=O)=O)OCCO4)n2)cc(OC)c1OC -US07030262B2,8,CSCC[C@H](CO)NC(=O)OC(C)(C)C>>CSCC[C@H](C=O)NC(=O)OC(C)(C)C -US07378417B2,2,Cc1cc(-c2cc(C(F)(F)F)n3ncc(C(=O)O)c3n2)ccc1C(F)(F)F.Nc1cccc(S(=O)(=O)NC2CC2)c1>>Cc1cc(-c2cc(C(F)(F)F)n3ncc(C(=O)Nc4cccc(S(=O)(=O)NC5CC5)c4)c3n2)ccc1C(F)(F)F -US20070232628A1,6,CC(C)c1ccc(C(C(N)=O)C2(C)OCCO2)cc1>>CC(=O)C(C(N)=O)c1ccc(C(C)C)cc1 -US20150038708A1,2,CNCC(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CN(CC(=O)N(Cc1ccc(C2CCCCC2)cc1)c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1)S(=O)(=O)c1ccc([N+](=O)[O-])cc1 -US07618978B2,6,CC[C@H](C)Nc1cc(C(=O)OC)cc(CC(C)(F)F)n1>>CC[C@H](C)Nc1cc(C(=O)O)cc(CC(C)(F)F)n1 -US05061718,1,CCCCC1(CCCC)CCc2c(O)cccc2C1=O.ClCc1ccc2ccccc2n1>>CCCCC1(CCCC)CCc2c(OCc3ccc4ccccc4n3)cccc2C1=O -US20140171404A1,6,CC(C)(C)OC(=O)NC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1>>NC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1 -US20140249154A1,4,CC(Br)C(=O)c1ccccn1.NC(=S)Nc1ncccn1>>Cc1sc(Nc2ncccn2)nc1-c1ccccn1 -US06121316,6,CCOC(=O)C[C@@H](C)O[Si](C(C)C)(C(C)C)C(C)C>>CC(C)[Si](O[C@H](C)CC(=O)O)(C(C)C)C(C)C -US07615550B2,6,CC(C)(C)OC(=O)N1CCCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1>>c1cc(OCCCN2CCCCC2)ccc1CN1CCCNCC1 -US20100179109A1,6,COC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1-c1ccccc1>>CN(Cc1ccc(C(=O)O)c(-c2ccccc2)c1)C(=O)OC(C)(C)C -US20090036492A1,1,CCC#CCOc1cc(C)c(C=O)c(C)c1C.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCC#CCOc1cc(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c(C)c1C -US05292770,6,COC(=O)C/C=C/c1ccc(Nc2ncccn2)cc1>>O=C(O)C/C=C/c1ccc(Nc2ncccn2)cc1 -US20090312382A1,6,Cc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1c1cccc(-c2cccc(S(C)(=O)=O)c2)c1>>Cc1ccccc1N1CCNCC1c1cccc(-c2cccc(S(C)(=O)=O)c2)c1 -US20140107073A1,9,Cc1cc(-c2ncccc2-c2ccnc(Cl)n2)ccc1F.N>>Cc1cc(-c2ncccc2-c2ccnc(N)n2)ccc1F -US20070124152A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccccc3)cc2n(Cc2ccc(S(C)(=O)=O)cc2)c1=O.NCc1ccco1>>CS(=O)(=O)c1ccc(Cn2c(=O)c(C(=O)NCc3ccco3)c(O)c3ncc(Cc4ccccc4)cc32)cc1 -US06919371B2,6,CCOC(=O)c1ccc2c(c1)CC[C@H](CN(C[C@H](O)c1ccc(-n3c(C)ccc3C)nc1)C(=O)OC(C)(C)C)O2>>Cc1ccc(C)n1-c1ccc([C@@H](O)CN(C[C@H]2CCc3cc(C(=O)O)ccc3O2)C(=O)OC(C)(C)C)cn1 -US07560463B2,1,NC(=O)c1ccc(Oc2ccc(C=O)cc2)cn1.NCCc1csc2ccccc12>>NC(=O)c1ccc(Oc2ccc(CNCCc3csc4ccccc34)cc2)cn1 -US08293768B2,2,Cc1nc(N2CCN(CC3CCCCC3)C2=O)sc1C(=O)O.NCc1cccnc1>>Cc1nc(N2CCN(CC3CCCCC3)C2=O)sc1C(=O)NCc1cccnc1 -US20100204226A1,7,Cc1cc([N+](=O)[O-])ccc1Oc1c(C)cccc1C>>Cc1cc(N)ccc1Oc1c(C)cccc1C -US06159979,3,Nc1ccc(Br)c2ccccc12.OB(O)c1ccncc1>>Nc1ccc(-c2ccncc2)c2ccccc12 -US20140206727A1,2,Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(N)c1.O=C(Cl)c1ccccc1>>Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(NC(=O)c2ccccc2)c1 -US20050070542A1,3,CC(C)[Mg+].COc1cccc(Cl)n1>>COc1cccc(C(C)C)n1 -US20060270692A1,2,CC(C)(C)OC(=O)N1CCC(CO)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)C1 -US20060217373A1,1,COCCOc1ccc(-c2c(C#N)c(N)nc(S)c2C#N)cc1.Cc1nc(CCl)cs1>>COCCOc1ccc(-c2c(C#N)c(N)nc(SCc3csc(C)n3)c2C#N)cc1 -US05071846,1,CCOC(=O)N1CCC(Nc2nc3ccccc3[nH]2)C1.ClCc1cscn1>>CCOC(=O)N1CCC(Nc2nc3ccccc3n2Cc2cscn2)C1 -US08716280B2,6,CCOC(=O)c1cnc2ccc(OC)nc2c1>>COc1ccc2ncc(C(=O)O)cc2n1 -US20070066624A1,1,CC(C)C[C@@H]1CN(C2CCCC2)C(=O)N1C1CCNCC1.COC(=O)Cc1ccc(Oc2ccc(C=O)c(C)n2)cc1>>COC(=O)Cc1ccc(Oc2ccc(CN3CCC(N4C(=O)N(C5CCCC5)C[C@H]4CC(C)C)CC3)c(C)n2)cc1 -US20080004263A1,2,Cc1onc(-c2cccc(Br)c2)c1-c1csc(C2CCNCC2)n1.O=S(=O)(Cl)Cc1ccccc1>>Cc1onc(-c2cccc(Br)c2)c1-c1csc(C2CCN(S(=O)(=O)Cc3ccccc3)CC2)n1 -US08785443B2,2,COC(=O)/C=C/C(=O)O.COCCN(CCOC)C(=O)[C@H](C)O>>COCCN(CCOC)C(=O)[C@H](C)OC(=O)/C=C/C(=O)OC -US20130040949A1,2,CC(=O)Cl.Cc1cnc(N)cn1>>CC(=O)Nc1cnc(C)cn1 -US20060167000A1,7,NC(=O)c1c(Cl)cc(Cl)c(O)c1[N+](=O)[O-]>>NC(=O)c1c(Cl)cc(Cl)c(O)c1N -US20120277220A1,6,CC(C)(C)OC(=O)NCCCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc(N4CCOCC4)cc3)nc21>>NCCCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc(N4CCOCC4)cc3)nc21 -US20060025327A1,1,Clc1ccc2c(Cl)ccnc2c1.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2cc(N3CCN(c4ccnc5cc(Cl)ccc45)CC3)c(F)cc2c1=O -US08785494B2,7,COC(=O)C=Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(F)(F)F>>COC(=O)CCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(F)(F)F -US05034417,2,CS(=O)(=O)Cl.NC(=O)c1ccc(N)c(Sc2ccc(F)cc2F)c1>>CS(=O)(=O)Nc1ccc(C(N)=O)cc1Sc1ccc(F)cc1F -US20130267571A1,1,BrCc1ccccc1.CC(C)=CCC/C(C)=C/CO>>CC(C)=CCC/C(C)=C/COCc1ccccc1 -US20110217311A1,6,COC(=O)c1sc2ncnc(Nc3cccnc3OC3CCC(NC(=O)OC(C)(C)C)CC3)c2c1C>>Cc1c(C(=O)O)sc2ncnc(Nc3cccnc3OC3CCC(NC(=O)OC(C)(C)C)CC3)c12 -US20140113882A1,1,COc1cncc2nc(-c3ccnc(Cl)c3)nc(O)c12.O[C@@H]1CCCNC1>>COc1cncc2nc(-c3ccnc(Cl)c3)nc(N3CCC[C@@H](O)C3)c12 -US07217711B2,7,COC(=O)c1cc(C)c2nc(C)c(C)nc2c1>>Cc1nc2cc(CO)cc(C)c2nc1C -US20150196566A1,9,Cn1cc(-c2nccnc2Cl)cn1>>Cn1cc(-c2cnccn2)cn1 -US20100105655A1,2,COc1cc(C(=O)O)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1.OCCN1CCNCC1>>COc1cc(C(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 -US20110054017A1,3,COC(=O)CCCCCCNC(=O)c1c(C)oc(-c2ccccc2)c1Br.COc1ccc(B(O)O)cc1>>COC(=O)CCCCCCNC(=O)c1c(C)oc(-c2ccccc2)c1-c1ccc(OC)cc1 -US20140377265A1,6,COC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C#N)cc1)n2C)c1ccccc1>>Cn1c(CNc2ccc(C#N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3ccccc3)ccc21 -US04711890,2,CNC1CCCCC1.O=C(O)c1cc(-c2ccccc2)nc2ccccc12>>CN(C(=O)c1cc(-c2ccccc2)nc2ccccc12)C1CCCCC1 -US20140275129A1,2,COc1ccc2c(c1OC)CCNC2.COc1cccc(-c2nc(C(=O)O)c3ccccc3n2)c1>>COc1cccc(-c2nc(C(=O)N3CCc4c(ccc(OC)c4OC)C3)c3ccccc3n2)c1 -US20120035132A1,1,CC(C)OCCOc1nc(Cl)c(Cl)cc1C#N.OB1OCc2cc(O)c(F)cc21>>CC(C)OCCOc1nc(Oc2cc3c(cc2F)B(O)OC3)c(Cl)cc1C#N -US20020086858A1,7,Cc1cc(N2CCCC2)nc(/C=C/c2cccc([N+](=O)[O-])c2)n1>>Cc1cc(N2CCCC2)nc(/C=C/c2cccc(N)c2)n1 -US08546387B2,2,CC(C)(C)c1cc(N=C=O)n(-c2ccccc2)n1.Nc1cccc(Oc2ccnc3ncc(=O)[nH]c23)c1>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3ccnc4ncc(=O)[nH]c34)c2)n(-c2ccccc2)n1 -US08299267B2,2,CCOC(=O)c1cc(C(=O)O)cc(C(=O)OCC)c1.CN>>CCOC(=O)c1cc(C(=O)NC)cc(C(=O)OCC)c1 -US20120264733A1,2,C1COCCN1.CC(C)CN(C(=O)c1nnn(-c2ccccc2)c1CO)[C@H]1C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C1>>CC(C)CN(C(=O)c1nnn(-c2ccccc2)c1CO)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1 -US03968138,9,CCN(CC)c1c([N+](=O)[O-])cc(C)c(Cl)c1[N+](=O)[O-].N>>CCN(CC)c1c([N+](=O)[O-])cc(C)c(N)c1[N+](=O)[O-] -US20150141433A1,3,CB1OB(C)OB(C)O1.COC(=O)c1cnc(Cl)c(C(F)(F)F)n1>>COC(=O)c1cnc(C)c(C(F)(F)F)n1 -US20090018122A1,1,NCC1CCOCC1.O=[N+]([O-])c1cnc2cc(OCc3ccccc3)ccc2c1Cl>>O=[N+]([O-])c1cnc2cc(OCc3ccccc3)ccc2c1NCC1CCOCC1 -US20140213599A1,1,C[C@H](N)CO.Clc1cc(Cl)nc(Cl)n1>>C[C@@H](CO)Nc1cc(Cl)nc(Cl)n1 -US20100331335A1,2,N#Cc1ccc2c(ccc(=O)n2CC(=O)O)c1.Nc1scc(Cl)c1-c1nc[nH]n1>>N#Cc1ccc2c(ccc(=O)n2CC(=O)Nc2scc(Cl)c2-c2nc[nH]n2)c1 -US06329392B1,1,COC(=O)c1ccccc1O.ICCCI>>COC(=O)c1ccccc1OCCCI -US06780992B2,1,CCc1nc(C)c(CC)c(=O)[nH]1.O=Cc1ccc(OCCBr)cc1>>CCc1c(C)nc(CC)n(CCOc2ccc(C=O)cc2)c1=O -US05852011,7,O=[N+]([O-])c1cccc(N(CCCl)CCCl)c1>>Nc1cccc(N(CCCl)CCCl)c1 -US20130338175A1,6,COC(=O)c1ccc(CCc2c[nH]c3[nH]c(N)nc(=O)c23)cc1>>Nc1nc(=O)c2c(CCc3ccc(C(=O)O)cc3)c[nH]c2[nH]1 -US05736534,6,COc1cc2ncnc(N3CCc4ccc(C#C[Si](C)(C)C)cc43)c2cc1OC>>C#Cc1ccc2c(c1)N(c1ncnc3cc(OC)c(OC)cc13)CC2 -US20100168418A1,1,COc1cc(C=O)cc2c1OCCO2.COc1ccc2ncc(=O)n(CCN3CCC(N)CC3)c2c1>>COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc(OC)c5c(c4)OCCO5)CC3)c2c1 -US20040157817A1,2,CC(C)S(=O)(=O)Cl.CC(C)S(=O)(=O)NC1CCC=C1c1ccc(OCCN)cc1>>CC(C)S(=O)(=O)NCCOc1ccc(C2=CCCC2NS(=O)(=O)C(C)C)cc1 -US20120270865A2,6,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2sc3ccccc3c2C)C2CCCCC2)cn1>>Cc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)nc2)C2CCCCC2)sc2ccccc12 -US20070219210A1,2,CC(C)(NC(=O)OCc1ccccc1)C(=O)O.CNC>>CN(C)C(=O)C(C)(C)NC(=O)OCc1ccccc1 -US20090281139A1,2,CCOC(=O)Cc1ccc(Br)cc1.CNOC>>CON(C)C(=O)Cc1ccc(Br)cc1 -US20070259849A1,1,CNC.Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1NC(=O)c1cccc(Br)n1>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1NC(=O)c1cccc(N(C)C)n1 -US20120121615A1,2,CC(C)(C)OC(=O)NCCOCCOCCOCCN.O=C(O)CCCCC(=O)O>>CC(C)(C)OC(=O)NCCOCCOCCOCCNC(=O)CCCCC(=O)O -US08431695B2,3,CC1(C)OB(c2ccc3cn(Cc4ccccc4)nc3c2)OC1(C)C.Nc1ncnn2c(CCCO)cc(Br)c12>>Nc1ncnn2c(CCCO)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12 -US05081253,8,COc1cccc(CSc2nc3cnccc3[nH]2)c1.OO>>COc1cccc(CS(=O)c2nc3cnccc3[nH]2)c1 -US08324216B2,2,COc1cc(N2CCNCC2)ccc1Cl.CS(=O)(=O)Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O>>COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3CS(C)(=O)=O)CC2)ccc1Cl -US20150274704A1,1,Cc1cnc(Cl)nc1NC1CCC2(CC1)CCN(C(=O)OC(C)(C)C)CC2.Cn1cc(N)cn1>>Cc1cnc(Nc2cnn(C)c2)nc1NC1CCC2(CC1)CCN(C(=O)OC(C)(C)C)CC2 -US07202363B2,3,C#CCCO.Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(I)cnc(N)c34)cc2)c1>>Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCCO)cnc(N)c34)cc2)c1 -US08293768B2,1,Cc1nc(-n2cnn(CCO)c2=O)sc1C(=O)NCc1cccnc1.Fc1ccc(CBr)cc1>>Cc1nc(-n2cnn(CCOCc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cccnc1 -US20070225303A1,2,CO.COc1ccc(C(=O)O)cc1C>>COC(=O)c1ccc(OC)c(C)c1 -US20070049604A1,8,CC(C)Cc1cc(CO)nn1C(C)(C)C>>CC(C)Cc1cc(C=O)nn1C(C)(C)C -US20080214615A1,6,CN(Cc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)C(=O)OC(C)(C)C>>CNCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O -US07557127B2,3,C=CC(=O)OCC.Cc1cc(I)cnc1Br>>CCOC(=O)/C=C/c1cnc(Br)c(C)c1 -US05866564,6,COc1ccc(CS[C@H]2C[C@@H](C(=O)N[C@H]3CCN(C(=O)OC(C)(C)C)C3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N[C@H]3CCNC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1 -US20110201815A1,4,CCOC(=O)C(Cl)C(C)=O.NC(=S)c1cc(O)c2sccc2c1>>CCOC(=O)c1sc(-c2cc(O)c3sccc3c2)nc1C -US20110144081A1,2,CN(C(=O)Oc1ccc(F)cc1)[C@H]1CN(C(=O)C2CCNCC2)C[C@@H]1c1ccc(Cl)c(Cl)c1.COCC(=O)Cl>>COCC(=O)N1CCC(C(=O)N2C[C@H](c3ccc(Cl)c(Cl)c3)[C@@H](N(C)C(=O)Oc3ccc(F)cc3)C2)CC1 -US20140179662A1,1,Clc1ncnc(Cl)n1.Nc1cccc(CS(N)(=O)=O)c1>>NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1 -US20080051398A1,1,CI.COc1cccc(Nc2nc(Cl)nc3ccccc23)c1OC>>COc1cccc(N(C)c2nc(Cl)nc3ccccc23)c1OC -US20070249670A1,2,Nc1cc(-c2ccccc2)sc1C(=O)O.O=C=Nc1c(Cl)cccc1Cl>>O=C(Nc1cc(-c2ccccc2)sc1C(=O)O)Nc1c(Cl)cccc1Cl -US06693123B2,3,COC(=O)c1ccc(COc2cccnc2)cc1OS(=O)(=O)C(F)(F)F.Cc1ccccc1B(O)O>>COC(=O)c1ccc(COc2cccnc2)cc1-c1ccccc1C -US20070043003A1,5,O=Cc1ccc([N+](=O)[O-])cc1.OCCO>>O=[N+]([O-])c1ccc(C2OCCO2)cc1 -US20040198982A1,1,COC(=O)C(Br)CC(C)C.Sc1nnc(-c2ccccc2)[nH]1>>COC(=O)C(CC(C)C)Sc1nnc(-c2ccccc2)[nH]1 -US08138168B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CNCC(C)C1>>COC(=O)C1CC(C)CN(C(=O)OC(C)(C)C)C1 -US07994218B2,9,CC(C)OC(=O)[C@H](OCc1ccccc1)C(C)(C)COS(=O)(=O)CCCCl.[N-]=[N+]=[N-]>>CC(C)OC(=O)[C@H](OCc1ccccc1)C(C)(C)COS(=O)(=O)CCCN=[N+]=[N-] -US08362068B2,3,CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1cn2cc(Br)sc2n1)c1ccccc1.COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3cn4cc(NC(=O)[C@@H]5CCCN5C(=O)[C@@H](NC(=O)OC(C)(C)C)c5ccccc5)nc4s3)cc2)[nH]1)C(C)C -US20130252986A1,1,Cn1cc(CCl)cn1.N#Cc1cc(CCc2cc[nH]c(=O)n2)ccc1Oc1cccc(C(F)(F)F)c1>>Cn1cc(Cn2ccc(CCc3ccc(Oc4cccc(C(F)(F)F)c4)c(C#N)c3)nc2=O)cn1 -US08288419B2,7,CCOC(=O)c1cc(Cn2cc([N+](=O)[O-])cn2)on1>>O=[N+]([O-])c1cnn(Cc2cc(CO)no2)c1 -US05869682,2,CC[C@H]1CCN(C(C(=O)OC(C)(C)C)[C@@H]2CCCN2)[C@@H]1C(=O)O.NCc1cccc(Cl)c1>>CC[C@H]1CCN(C(C(=O)OC(C)(C)C)[C@@H]2CCCN2)[C@@H]1C(=O)NCc1cccc(Cl)c1 -US06803457B1,7,CC(C)(C)OC(=O)COc1ccc(Cl)cc1C#N>>CC(C)(C)OC(=O)COc1ccc(Cl)cc1CN -US20030013730A1,1,C=O.CN1CCN(c2nc3cc(Cl)c(N)cc3o2)CC1>>CNc1cc2oc(N3CCN(C)CC3)nc2cc1Cl -US07368578B2,1,COc1cc(CO)ccc1OCc1csc(N2CCCCC2)n1.O=Cc1cn(-c2ccccc2)nc1O>>COc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1csc(N2CCCCC2)n1 -US05877317,1,CN.O=C1CCN(Cc2ccccc2)CC1>>CNC1CCN(Cc2ccccc2)CC1 -US20150218194A1,6,COC(=O)N[C@H](C(=O)N1CCC[C@@]1(C(N)=O)c1ccc([C@H]2CC[C@H](c3ccc([C@]4(C(N)=O)CCCN4C(=O)[C@@H](NC(=O)OC)C(C)C)cc3)N2c2ccc(OC)cc2)cc1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@@]1(C(N)=O)c1ccc([C@H]2CC[C@H](c3ccc([C@]4(C(N)=O)CCCN4C(=O)[C@@H](NC(=O)OC)C(C)C)cc3)N2c2ccc(O)cc2)cc1)C(C)C -US07507740B2,1,CCOCCOCCBr.Clc1ncnc2cc[nH]c12>>CCOCCOCCn1ccc2ncnc(Cl)c21 -US07642267B2,6,CCn1c(Cn2ccnc2-c2cc(F)ccc2F)nc2cc(NC(C)=O)ccc21>>CCn1c(Cn2ccnc2-c2cc(F)ccc2F)nc2cc(N)ccc21 -US04677129,1,CC(C)CI.O=C1NC(=O)C2(c3ccc([N+](=O)[O-])cc3)CC1C2>>CC(C)CN1C(=O)C2CC(c3ccc([N+](=O)[O-])cc3)(C2)C1=O -US20030028022A1,1,C1COCCN1.O=Cc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1>>c1cnc2c(c1)CCCC2N(Cc1ccc(CN2CCOCC2)cc1)Cc1nc2ccccc2[nH]1 -US20080306109A1,6,CCOC(=O)Cc1c(C)c(Sc2nc3ccccc3s2)c2ccccn12>>Cc1c(Sc2nc3ccccc3s2)c2ccccn2c1CC(=O)O -US08063061B2,4,CCOCC(=O)CC(=O)c1ccc2c(c1)c1cc(-c3ccc(Cl)cc3Cl)c(=O)n(C)c1n2C.NN>>CCOCc1cc(-c2ccc3c(c2)c2cc(-c4ccc(Cl)cc4Cl)c(=O)n(C)c2n3C)[nH]n1 -US20080207650A1,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(C3CCSCC3)c2=O)CC1>>N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(C3CCSCC3)c2=O)CC1 -US20110039852A1,2,CC(=O)Cl.COC(=O)Cc1ccc(F)c(-c2ccc(C(F)(F)F)cc2CNCC(F)(F)F)c1>>COC(=O)Cc1ccc(F)c(-c2ccc(C(F)(F)F)cc2CN(CC(F)(F)F)C(C)=O)c1 -US07572809B2,3,Cc1cc(Nc2cc3ccccc3c(Cl)n2)n[nH]1.N#Cc1ccc(B(O)O)cc1>>Cc1cc(Nc2cc3ccccc3c(-c3ccc(C#N)cc3)n2)n[nH]1 -US04008066,9,COC(=O)CNc1c(C)cccc1C.N>>Cc1cccc(C)c1NCC(N)=O -US20110257225A1,7,CCN(C(=O)CCc1ccccc1)C1CCCCC1>>CCN(CCCc1ccccc1)C1CCCCC1 -US05541195,6,O=C(Cc1ccccn1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1>>O=C(Cc1ccccn1)N1CC[C@H](NCc2ccnc3ccccc23)C[C@H]1Cc1ccccc1 -US04370328,2,CNCCc1ccncc1.O=S(=O)(Cl)C1CCCCC1>>CN(CCc1ccncc1)S(=O)(=O)C1CCCCC1 -US20120277237A1,3,C#CCCc1nc2ccccc2nc1C.FCc1cccc(Br)n1>>Cc1nc2ccccc2nc1CCC#Cc1cccc(CF)n1 -US05962514,1,COc1ccc(F)c2c1C[C@@H](NC1CCCC1)CO2.O=C1CCC1>>COc1ccc(F)c2c1C[C@@H](N(C1CCCC1)C1CCC1)CO2 -US20070066615A1,1,O=C1NC(=O)c2ccccc21.OC[C@H]1CO1>>O=C1c2ccccc2C(=O)N1C[C@H]1CO1 -US03931204,1,CCO.Clc1nc(Cl)c2cscc2n1>>CCOc1nc(Cl)nc2cscc12 -US20070060566A1,3,O=C(Nc1ccc2c(c1)CCN(C1CCC1)CC2)c1ccc(I)cc1.OB(O)c1ccncc1>>O=C(Nc1ccc2c(c1)CCN(C1CCC1)CC2)c1ccc(-c2ccncc2)cc1 -US20120142633A1,2,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](N)CC1.COc1ccc(OCC2CC2)c(-c2ccnc3c(C(=O)O)c(C)n(COCC[Si](C)(C)C)c23)c1>>COc1ccc(OCC2CC2)c(-c2ccnc3c(C(=O)N[C@@H]4CC[C@H](NC(=O)OC(C)(C)C)CC4)c(C)n(COCC[Si](C)(C)C)c23)c1 -US03954734,1,C1CCN(C2CCNCC2)C1.N#Cc1ccc(-c2ccc(F)cc2)[nH]c1=O>>N#Cc1ccc(-c2ccc(N3CCC(N4CCCC4)CC3)cc2)[nH]c1=O -US20140322650A1,2,COCCOCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>COCCOCCOS(=O)(=O)c1ccc(C)cc1 -US20070281946A1,2,C1COCCN1.O=C(Nc1nccs1)C(CC1CCOCC1)c1ccc(S(=O)(=O)Cl)cc1>>O=C(Nc1nccs1)C(CC1CCOCC1)c1ccc(S(=O)(=O)N2CCOCC2)cc1 -US07265246B2,6,O=C1c2ccccc2C(=O)N1Cc1cnc(-c2ccccc2)o1>>NCc1cnc(-c2ccccc2)o1 -US20100160255A1,2,CC(=O)OC(C)=O.CCNC(=O)Nc1sc2c(c1C(=O)N1CCC(N3CCCC4(C3)CC(C)(C)OC4=O)CC1)CCNC2>>CCNC(=O)Nc1sc2c(c1C(=O)N1CCC(N3CCCC4(C3)CC(C)(C)OC4=O)CC1)CCN(C(C)=O)C2 -US07375087B2,5,COCCl.Cc1cc(O)ccc1Br>>COCOc1ccc(Br)c(C)c1 -US20070082890A1,2,CCOC(=O)Cc1c(C)n[nH]c1C.NN>>Cc1n[nH]c(C)c1CC(=O)NN -US05292740,1,COc1ccc(F)cc1Oc1c(Cl)ncnc1Cl.NS(=O)(=O)c1ccc(C(F)(F)F)cc1>>COc1ccc(F)cc1Oc1c(Cl)ncnc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1 -US20150232481A1,7,COc1cc(F)c(F)cc1CC(=O)O>>COc1cc(F)c(F)cc1CCO -US20120142705A1,7,COc1ccc2c(c1)C(=O)C(=O)N2C(CC1CCCC1)C(=O)O>>COc1ccc2c(c1)CC(=O)N2C(CC1CCCC1)C(=O)O -US20100004245A1,1,CCC(C)c1ccccc1OC1CCNCC1.CCOC(=O)c1cncc(-c2cnc(Br)nn2)c1>>CCOC(=O)c1cncc(-c2cnc(N3CCC(Oc4ccccc4C(C)CC)CC3)nn2)c1 -US06949648B2,1,Cc1cccc(-n2nc(C)cc2N)n1.O=C(O)c1ccccc1I>>Cc1cccc(-n2nc(C)cc2Nc2ccccc2C(=O)O)n1 -US20110112103A1,5,CC(C)(C)OC(=O)c1nc(CCl)nc(O)c1OCc1ccccc1.COCCl>>COCOc1nc(CCl)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1 -US20150191464A1,2,CC(C)Nc1cc(Cl)ncc1C(=O)O.NCCC1(O)CCOCC1>>CC(C)Nc1cc(Cl)ncc1C(=O)NCCC1(O)CCOCC1 -US20130196974A1,1,CS(=O)(=O)c1ccc2c(c1)CCCN(c1cc(Cl)c3ccccc3n1)C2.NCCN>>CS(=O)(=O)c1ccc2c(c1)CCCN(c1cc(NCCN)c3ccccc3n1)C2 -US20130045986A1,3,CC(C)OC(=O)N1CCC(c2nc3cc(Br)ccc3o2)CC1.O=Cc1ccc(B(O)O)cc1>>CC(C)OC(=O)N1CCC(c2nc3cc(-c4ccc(C=O)cc4)ccc3o2)CC1 -US08158790B2,2,CC(C)[C@H](C/C=C/COCc1ccccc1)C(=O)O.CNC>>CC(C)[C@H](C/C=C/COCc1ccccc1)C(=O)N(C)C -US04657579,1,COc1ncnc(OC)c1NC(=O)CCl.ClCc1cc[nH]n1>>COc1ncnc(OC)c1N(Cc1cc[nH]n1)C(=O)CCl -US20020007045A1,6,CC(C)N(CC(O)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CNC(=O)OC(C)(C)C)cc1>>CC(C)N(CC(O)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CN)cc1 -US08765730B2,3,CON(C)C(=O)CC(c1ccc(Br)cc1)c1ccccc1C.Fc1cc(I)c(Cl)cn1>>Cc1ccccc1C(CC(=O)c1cc(F)ncc1Cl)c1ccc(Br)cc1 -US06429214B1,2,Cc1ccc(S(N)(=O)=O)cc1.N=C(N)NCCCOc1ccc2c(c1)NC(=O)C(CC(=O)O)C2>>Cc1ccc(S(=O)(=O)NC(=O)CC2Cc3ccc(OCCCNC(=N)N)cc3NC2=O)cc1 -US20100004232A1,4,Nc1ccc(CN2CCOCC2)cc1N.O=C(O)c1n[nH]cc1[N+](=O)[O-]>>O=[N+]([O-])c1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1 -US08383621B2,6,O=C1CN(Cc2ccccc2)CC(=O)N1>>O=C1CNCC(=O)N1 -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1.COc1cccc(OCCCCBr)c1>>COc1cccc(OCCCCN2CCC(CNC(=O)c3cc(Cl)c(N)cc3OC)CC2)c1 -US05952321,2,C=CC[C@@H](N=C=O)c1ccc(C)cc1.CCC1(CC)C(=O)NC1Oc1ccc(C(=O)CCC#N)cc1>>C=CC[C@@H](NC(=O)N1C(=O)C(CC)(CC)[C@@H]1Oc1ccc(C(=O)CCC#N)cc1)c1ccc(C)cc1 -US20100041892A1,7,CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC)cc1Oc1ncc(Cl)cc1Cl>>CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCCOC)cc1Oc1ncc(Cl)cc1Cl -US08299267B2,2,CS(=O)(=O)Cl.N#Cc1cc(N)cc(Br)c1>>CS(=O)(=O)Nc1cc(Br)cc(C#N)c1 -US07476666B2,9,CCOC(=O)c1nn2c(c1OCc1ccccc1)C(=O)N(C)CC2C(N)=O>>CCOC(=O)c1nn2c(c1OCc1ccccc1)C(=O)N(C)CC2C#N -US08309581B2,1,BrCC1CCCC1.N#Cc1ccc(Cn2c(-c3ccc(Cl)cc3O)nc3cc(F)c(F)cc32)c(F)c1>>N#Cc1ccc(Cn2c(-c3ccc(Cl)cc3OCC3CCCC3)nc3cc(F)c(F)cc32)c(F)c1 -US20150266848A1,7,CC(C)(C)C(=O)OCC[C@@H]1OC2(CCCC2)O[C@H]1c1ccccc1>>OCC[C@@H]1OC2(CCCC2)O[C@H]1c1ccccc1 -US04439617,6,COC(=O)CN(C)C(=O)c1cccc2c(Br)cccc12>>CN(CC(=O)O)C(=O)c1cccc2c(Br)cccc12 -US05681954,1,COc1cc2[nH]nc(CN3CCN(c4ccccc4OC)CC3)c2cc1OC.COc1ccc(CCl)cc1OC>>COc1ccc(Cn2nc(CN3CCN(c4ccccc4OC)CC3)c3cc(OC)c(OC)cc32)cc1OC -US20110053931A1,2,COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCN(C)CC1.Cc1cc(C(=O)O)c(=O)n(-c2ccc(F)cc2)n1>>COc1cc2c(Oc3ccc(NC(=O)c4cc(C)nn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 -US08178577B2,2,COC(=O)CCCCCN.O=C(O)C=C1c2ccccc2-c2ccccc21>>COC(=O)CCCCCNC(=O)C=C1c2ccccc2-c2ccccc21 -US05919793,1,BrCc1ccc(Br)cc1.COCCO>>COCCOCc1ccc(Br)cc1 -US20120046269A1,1,CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(N)c1.CCOC(=O)c1cnc(Cl)o1>>CCOC(=O)c1cnc(Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)o1 -US05910494,7,CCCC[C@]1(CC)CSc2cc(OC)ccc2C(c2ccccc2)=N1>>CCCC[C@]1(CC)CSc2cc(OC)ccc2[C@@H](c2ccccc2)N1 -US20090124600A1,6,CC(C)(C)OC(=O)NC1CCN(CC(O)Cc2ccccc2)C1>>NC1CCN(CC(O)Cc2ccccc2)C1 -US05010093,2,CCOC(=O)c1cscn1.NCCO>>O=C(NCCO)c1cscn1 -US20030162795A1,1,NC(=O)C1CCNCC1.O=Cc1ccc(-c2cc3nccc(Nc4ccc5[nH]ccc5c4)c3s2)cc1>>NC(=O)C1CCN(Cc2ccc(-c3cc4nccc(Nc5ccc6[nH]ccc6c5)c4s3)cc2)CC1 -US20110039852A1,2,CCNCc1cc(C(F)(F)F)ccc1-c1cc(Cl)cc(CC(=O)OCC)c1.O=C(Cl)C1CC1>>CCOC(=O)Cc1cc(Cl)cc(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)C2CC2)c1 -US08324216B2,1,CCOC(=O)c1c(-c2cc(C)on2)n[nH]c1C.COc1cc(N2CCN(C(=O)CCl)[C@@H](C)C2)ccc1Cl>>CCOC(=O)c1c(-c2cc(C)on2)nn(CC(=O)N2CCN(c3ccc(Cl)c(OC)c3)CC2C)c1C -US20110257208A1,1,Cc1nc(C)c(C=O)s1.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>Cc1nc(C)c(CN2Cc3ncnc(Nc4cnc5ccccc5c4)c3C2)s1 -US05185363,1,CCCCBr.O=Cc1ccc(O)cc1>>CCCCOc1ccc(C=O)cc1 -US06476021B1,1,ClCCN1CCCCC1.O=c1c(Cc2cncnc2)cn2c3c(cc(O)cc13)Sc1ccc(Br)cc1-2>>O=c1c(Cc2cncnc2)cn2c3c(cc(OCCN4CCCCC4)cc13)Sc1ccc(Br)cc1-2 -US08802864B2,2,CCN=C=O.O=c1[nH]nc(C[C@@H]2CCNC2)n1-c1ccc(Br)cc1F>>CCNC(=O)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(Br)cc2F)C1 -US20110201592A1,6,CC(C)(C)OC(=O)N1CC[C@H](Nc2nc(-c3ccccc3O)nc3ccc(C#CCO)cc23)C1>>OCC#Cc1ccc2nc(-c3ccccc3O)nc(N[C@H]3CCNC3)c2c1 -US08586617B2,1,Nc1nc(Cl)cc(Cl)n1.O=Cc1c[nH]cn1>>Clc1cc(Cl)nc(NCc2c[nH]cn2)n1 -US06555584B1,2,CC(C)=CC(=O)Cl.NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1>>CC(C)=CC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1 -US05114936,1,O=C1c2c(-c3ccccc3F)noc2CCC1CCCCl.c1ccc2c(N3CCNCC3)nsc2c1>>O=C1c2c(-c3ccccc3F)noc2CCC1CCCN1CCN(c2nsc3ccccc23)CC1 -US08501750B2,1,CC(C)(C)C(=O)CBr.CCc1cc2c(=O)[nH]c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1>>CCc1cc2c(=O)n(CC(=O)C(C)(C)C)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1 -US08980889B2,1,COC(=O)c1ccnc(N)c1.O=C(c1ccccc1)C(F)(F)F>>COC(=O)c1ccnc(/N=C(/c2ccccc2)C(F)(F)F)c1 -US20070197472A1,1,CC#CC(C)(C)NC(=O)C(Br)CC.Oc1ccc2ncoc2c1>>CC#CC(C)(C)NC(=O)C(CC)Oc1ccc2ncoc2c1 -US20120004269A1,3,C#CC(O)(CCC)CCC.O=C(NCCc1cccc(Br)c1)C(F)(F)F>>CCCC(O)(C#Cc1cccc(CCNC(=O)C(F)(F)F)c1)CCC -US20130296327A1,6,CO[C@@H]1CC[C@@H](N2C(=O)c3ccccc3C2=O)CC1>>CO[C@@H]1CC[C@@H](N)CC1 -US20110071194A1,5,C[C@H](N)[C@H](Oc1ccc2c(cnn2-c2cccc(CO)c2)c1)c1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C[C@H](NC(=O)C(F)(F)F)[C@H](Oc1ccc2c(cnn2-c2cccc(CO)c2)c1)c1ccccc1 -US20080318943A1,3,COc1ccc(B(O)O)c(OC)n1.Nc1c2c(nc3c(Br)cccc13)CN(C1CCC1)C2=O>>COc1ccc(-c2cccc3c(N)c4c(nc23)CN(C2CCC2)C4=O)c(OC)n1 -US07229987B2,1,CC(C)(C)OC(=O)N1CCCN(CCCCl)CC1.Oc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1>>CC(C)(C)OC(=O)N1CCCN(CCCOc2ccc(-c3nnc(CSCCOc4ccccc4)o3)cc2)CC1 -US08916599B2,7,CNc1ccc(C(=O)Nc2ccc(Br)cc2)cc1[N+](=O)[O-]>>CNc1ccc(C(=O)Nc2ccc(Br)cc2)cc1N -US04324786,1,O=C(Cl)c1cccnc1.c1ccc(CN2CCN(C3=Nc4ncccc4NN3)CC2)cc1>>O=C(c1cccnc1)N1NC(N2CCN(Cc3ccccc3)CC2)=Nc2ncccc21 -US07790895B2,3,CCOC(=O)c1cnc2cc(C(F)(F)F)ccc2c1OS(=O)(=O)C(F)(F)F.OB(O)c1ccc(-c2ccccc2)cc1>>CCOC(=O)c1cnc2cc(C(F)(F)F)ccc2c1-c1ccc(-c2ccccc2)cc1 -US20150265617A1,3,F[C@@H]1CCN(CCn2nc(I)c3c(Cl)c(-c4ccccc4)nnc32)C1.OB(O)c1ccc(F)cc1>>Fc1ccc(-c2nn(CCN3CC[C@@H](F)C3)c3nnc(-c4ccccc4)c(Cl)c23)cc1 -US06727264B1,1,O=C(CCCCl)c1ccc(Br)cc1.O=C(Nc1cccc(C2CCNCC2)c1)C1CC1>>O=C(CCCN1CCC(c2cccc(NC(=O)C3CC3)c2)CC1)c1ccc(Br)cc1 -US20130102599A1,3,CCCC[Sn](CCCC)(CCCC)c1cscn1.Cc1ccccc1-n1nc2c3ccccc3n(Cc3ccc(Br)nc3)nc-2c1=O>>Cc1ccccc1-n1nc2c3ccccc3n(Cc3ccc(-c4cscn4)nc3)nc-2c1=O -US20140288088A1,6,CC(C)(C)OC(=O)N1CCN(c2cc3ccc(C#N)cc3cn2)C(=O)C1>>N#Cc1ccc2cc(N3CCNCC3=O)ncc2c1 -US20140024650A1,7,CCOC(=O)C1=C(N[C@@H](C)c2ccccc2)CCOC1>>CCOC(=O)[C@@H]1COCC[C@@H]1N[C@@H](C)c1ccccc1 -US20150065705A1,6,CC(C)(C)OC(=O)N1CC=C(c2ccc(F)cc2)[C@@H](OC(=O)C(C)(C)C)C1>>CC(C)(C)C(=O)O[C@H]1CNCC=C1c1ccc(F)cc1 -US06498165B1,3,CSc1nccc(Cl)n1.C[C@H](Nc1nccc(-n2cnc3cc([Sn](C)(C)C)ccc32)n1)c1ccccc1>>CSc1nccc(-c2ccc3c(c2)ncn3-c2ccnc(N[C@@H](C)c3ccccc3)n2)n1 -US20050239836A1,1,CC(C)(C)c1cccc(C2(NCC(O)C(N)Cc3cc(F)cc(F)c3)CCCCC2)c1.O=C(O)Cc1ccc(I)cc1>>CC(C)(C)c1cccc(C2(NCC(O)C(Cc3cc(F)cc(F)c3)Nc3ccc(CC(=O)O)cc3)CCCCC2)c1 -US20120041036A1,9,COC(=O)c1ccc2ccc(Br)c(O)c2c1.[C-]#N>>COC(=O)c1ccc2ccc(C#N)c(O)c2c1 -US20080125429A1,5,COCCl.Oc1ccc(I)cc1>>COCOc1ccc(I)cc1 -US20110275638A1,2,CC(C)(C)OC(=O)N1CCN(CCOC(=O)N[C@@](C)(Cc2ccc(O)cc2)C(=O)O)CC1.CC(C)CCN>>CC(C)CCNC(=O)[C@](C)(Cc1ccc(O)cc1)NC(=O)OCCN1CCN(C(=O)OC(C)(C)C)CC1 -US20060160864A1,1,CNCCOC.O=Cc1cc(Br)ccc1F>>COCCN(C)c1ccc(Br)cc1C=O -US20050234238A1,7,O=Cc1cc(Br)ccc1F>>OCc1cc(Br)ccc1F -US20140121200A1,1,O=[N+]([O-])c1ccc(F)cc1.OC1CCNCC1>>O=[N+]([O-])c1ccc(N2CCC(O)CC2)cc1 -US06437158B1,2,CCCCCCCCCCC(=O)Cl.C[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2CC[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12>>CCCCCCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3[C@H](C)CC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C -US20080139558A1,1,CC(C)(C)c1nc2ccccc2[nH]1.O=c1cc(CBr)c2ccc(F)c(F)c2[nH]1>>CC(C)(C)c1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 -US06943183B2,6,CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCc1c(O[C@H](Cn2ccnc2)c2ccccc2)ccc2c1CCCC2=O>>CSCC[C@H](N)C(=O)NCc1c(O[C@H](Cn2ccnc2)c2ccccc2)ccc2c1CCCC2=O -US20090099201A1,6,COC(=O)[C@@H]1CC[C@@H](C(=O)N2CCN(c3ccc(NC(=O)c4nc(-c5ccccc5)oc4C(F)(F)F)c(F)c3)CC2)CC1>>O=C(Nc1ccc(N2CCN(C(=O)[C@@H]3CC[C@@H](C(=O)O)CC3)CC2)cc1F)c1nc(-c2ccccc2)oc1C(F)(F)F -US05591846,4,CC(=O)OCC(CNC(=O)c1c(I)c(N)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I)OC(C)=O.O=C(Br)C(Br)CCBr>>CC(=O)OCC(CNC(=O)c1c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c(I)c(N2CCC(Br)C2=O)c1I)OC(C)=O -US07491748B2,5,COCCl.O=c1ccc2ccc(O)cc2o1>>COCOc1ccc2ccc(=O)oc2c1 -US20080032998A1,2,Cn1cccc1C1=CCNCC1.O=C(O)c1cc2ncc(Br)cn2n1>>Cn1cccc1C1=CCN(C(=O)c2cc3ncc(Br)cn3n2)CC1 -US08748426B2,6,CCCCCc1ccc(C(=O)Nc2ccc(-c3ccc4c(c3)C(=O)N([C@H](C(=O)OC)C(C)C)C4)c(OC)c2)cc1>>CCCCCc1ccc(C(=O)Nc2ccc(-c3ccc4c(c3)C(=O)N([C@H](C(=O)O)C(C)C)C4)c(OC)c2)cc1 -US05527811,7,CCOC(=O)/C=C/c1c(-c2ccccc2)c2cc(C)c(C)cc2c(=O)n1C>>CCOC(=O)CCc1c(-c2ccccc2)c2cc(C)c(C)cc2c(=O)n1C -US08877778B2,2,CC#CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1>>CC#CC(=O)N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1 -US08008494B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1 -US08436008B2,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CC1Cc2ccc(Br)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1>>CC1Cc2ccc(C3=CCN(C(=O)OC(C)(C)C)CC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1 -US20140323468A1,1,BrCc1cncc(Br)c1.C[S-]>>CSCc1cncc(Br)c1 -US05604213,7,CC(=O)O[C@@H]1CC[C@@]2(C)[C@@H](CC[C@@H]3[C@@H]2CC[C@]2(C)C(c4cccnc4)=CC[C@@H]32)C1>>C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cccnc3)=CC[C@@H]12 -US03931235,8,C#CCSc1c(O)cc(C)oc1=O.OO>>C#CCS(=O)c1c(O)cc(C)oc1=O -US20150266862A1,1,CCOC(=O)C1CNCCO1.O=Cc1cccc(Oc2ccccc2)c1>>CCOC(=O)C1CN(Cc2cccc(Oc3ccccc3)c2)CCO1 -US20020173646A1,1,COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1O.CSCCCO>>COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCCSC -US07087601B2,1,Brc1c[nH]cn1.COc1cc(-c2nc3ccccc3o2)ccc1CBr>>COc1cc(-c2nc3ccccc3o2)ccc1Cn1cnc(Br)c1 -US06716841B2,2,CCO.Nc1ccc(Br)cc1C(=O)O>>CCOC(=O)c1cc(Br)ccc1N -US08362068B2,2,CC(C)(C)OC(=O)NCC(=O)N1CCC[C@H]1C(=O)O.Nc1cn2cc(Br)sc2n1>>CC(C)(C)OC(=O)NCC(=O)N1CCC[C@H]1C(=O)Nc1cn2cc(Br)sc2n1 -US20120252779A1,7,Nc1cc(F)c(F)c(C(=O)O)c1F>>Nc1cc(F)c(F)c(CO)c1F -US07772253B2,6,COC(=O)c1cc(OC)cc(C2CC2)c1>>COc1cc(C(=O)O)cc(C2CC2)c1 -US20070010511A1,1,CC1(C)Oc2ccc(CO)cc2NC1=O.COCCCCl>>COCCCN1C(=O)C(C)(C)Oc2ccc(CO)cc21 -US20030199561A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O -US20100120775A1,6,COC(=O)c1ccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)ccc2n1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3nc(C(=O)O)ccc3c2)cc1 -US08637559B2,1,CCC(Br)CC.COc1ccc(-c2nc(CNC(=O)c3ncccc3C)co2)cc1O>>CCC(CC)Oc1cc(-c2nc(CNC(=O)c3ncccc3C)co2)ccc1OC -US07812022B2,1,COc1ccc(N)cc1N1CCN(C)CC1.O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Cl)n2)c1)c1c(F)cccc1F>>COc1ccc(Nc2nccc(-c3c(-c4cccc(NC(=O)c5c(F)cccc5F)c4)nn4ccccc34)n2)cc1N1CCN(C)CC1 -US04933355,3,O=C(O)CN1C(=O)CSC1=S.O=Cc1csc(NC2CCCCC2)n1>>O=C(O)CN1C(=O)C(=Cc2csc(NC3CCCCC3)n2)SC1=S -US20090111791A1,2,CCOc1ccccc1CN=C=O.Clc1ccc(OC2CCNCC2)cc1>>CCOc1ccccc1CNC(=O)N1CCC(Oc2ccc(Cl)cc2)CC1 -US06936602B1,1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3)cc1.O=Cc1nnn[nH]1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3Cc2nnn[nH]2)cc1 -US05981553,3,CCOC(=O)c1cc2c(Cl)cc(Cl)cc2[nH]1.CN(C)C=O>>CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1C=O -US05763700,7,COC(=O)C(F)=CC1(c2ccc(OC(F)F)cc2)CC1>>OCC(F)=CC1(c2ccc(OC(F)F)cc2)CC1 -US20080214815A1,2,C1CNC1.O=C(O)CN1CCN(C(=O)c2ccccc2)CC1>>O=C(CN1CCN(C(=O)c2ccccc2)CC1)N1CCC1 -US20030171411A1,2,CCOC(=O)Cc1csc(N)n1.O=C(Cl)C(Br)CC1CCCCC1>>CCOC(=O)Cc1csc(NC(=O)C(Br)CC2CCCCC2)n1 -US20100063068A1,2,CN.O=C(O)c1c(-c2ccccc2)nn2cc(I)ccc12>>CNC(=O)c1c(-c2ccccc2)nn2cc(I)ccc12 -US20140018533A1,3,CCOC(=O)C1=C(Nc2ccc(Br)cc2)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(Nc2ccc(Br)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O -US20070247585A1,6,CCOc1ccc2c(c1F)OC1CC3(CCC21)OCCO3>>CCOc1ccc2c(c1F)OC1CC(=O)CCC21 -US06699859B1,1,NNc1cc(N2CCCC2)c(Cl)nn1.O=Cc1ccccc1>>Clc1nnc(NN=Cc2ccccc2)cc1N1CCCC1 -US20130210769A1,1,CCOC(=O)N[C@H](CN)c1cccc(C(F)(F)F)c1.COc1ccc(C=O)cc1>>CCOC(=O)N[C@H](CNCc1ccc(OC)cc1)c1cccc(C(F)(F)F)c1 -US07625908B2,2,C#CCNCCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12.CC(=O)Cl>>C#CCN(CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(C)=O -US20070254910A1,1,CN.O=C1CCCc2cccnc21>>CNC1CCCc2cccnc21 -US03997603,7,CC(C)c1cc(S(N)(=O)=O)c(C(C)C)cc1C(=O)O>>CC(C)c1cc(S(N)(=O)=O)c(C(C)C)cc1CO -US20150031668A1,1,CC(C)(C)[S@](N)=O.O=C(c1ccc(OC(F)(F)F)c(F)c1)c1nccnc1Cl>>CC(C)(C)[S@@](=O)/N=C(/c1ccc(OC(F)(F)F)c(F)c1)c1nccnc1Cl -US20100137298A1,3,CCOC(=O)c1oc2cccc(OS(=O)(=O)C(F)(F)F)c2c1C.C[Si](C)(C)C#CC1CC1>>CCOC(=O)c1oc2cccc(C#CC3CC3)c2c1C -US20050124682A1,9,Clc1ccc2sc(-c3ccccc3)c(CBr)c2c1.[C-]#N>>N#CCc1c(-c2ccccc2)sc2ccc(Cl)cc12 -US07696223B2,2,CC(C)(C)C(=O)Cl.CCOC(=O)c1ncc2c(c1O)c(Br)c(Br)n2Cc1ccccc1>>CCOC(=O)c1ncc2c(c(Br)c(Br)n2Cc2ccccc2)c1OC(=O)C(C)(C)C -US05599814,9,COC(=O)c1nc2cc(Cl)ccc2c(Cl)c1C(=O)OC>>COC(=O)c1cc2ccc(Cl)cc2nc1C(=O)OC -US04055409,1,CC(=O)Cl.COC(=O)c1ccccc1-c1cc(-c2ccc(OC)cc2)[nH]n1>>COC(=O)c1ccccc1-c1cc(-c2ccc(OC)cc2)n(C(C)=O)n1 -US04489089,2,CC(CCN)n1ccnc1.O=C(Cl)c1ccc(Cl)s1>>CC(CCNC(=O)c1ccc(Cl)s1)n1ccnc1 -USH0000691,2,Cc1ccc(N)cc1.O=S(=O)(Cl)c1ccccc1>>Cc1ccc(NS(=O)(=O)c2ccccc2)cc1 -US20110160196A1,2,CC(=O)Cl.O=C(NCc1cn(-c2ccc(-n3ccccc3=O)cc2N2CCNCC2)nn1)c1ccc(Cl)s1>>CC(=O)N1CCN(c2cc(-n3ccccc3=O)ccc2-n2cc(CNC(=O)c3ccc(Cl)s3)nn2)CC1 -US20150175530A1,1,C=O.CC(C)(N)[C@H](NC(=O)c1ccc(C#CC#CC[C@H](O)CO)cc1)C(=O)NO>>CNC(C)(C)[C@H](NC(=O)c1ccc(C#CC#CC[C@H](O)CO)cc1)C(=O)NO -US06716831B1,1,Clc1ccnc(Cl)n1.c1ccc2c(c1)CCCN2>>Clc1nccc(N2CCCc3ccccc32)n1 -US06211234B1,1,CCOC(=O)CBr.Oc1ccc(OCc2ccccc2)cc1OCc1ccccc1>>CCOC(=O)COc1ccc(OCc2ccccc2)cc1OCc1ccccc1 -US20060166990A1,7,Cc1ccc(OCCCO)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1[N+](=O)[O-]>>Cc1ccc(OCCCO)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1N -US20080255105A1,6,CCOC(=O)c1ccc(-c2cc(NC(=O)c3cccs3)ccc2C)cc1>>Cc1ccc(NC(=O)c2cccs2)cc1-c1ccc(C(=O)O)cc1 -US20130331376A1,3,CC1(C)OB(c2ccncc2-c2ccccc2)OC1(C)C.CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C(C)C>>CC[C@@H]1C(=O)N(C)c2cnc(-c3ccncc3-c3ccccc3)nc2N1C(C)C -US07566699B2,1,CNOC.O=C(Cl)CCc1ccccc1>>CON(C)C(=O)CCc1ccccc1 -US20100160379A1,1,ClCc1ccccn1.O=Cc1cccc(O)c1>>O=Cc1cccc(OCc2ccccn2)c1 -US20060247238A1,1,CCOC(=O)CBr.O=C(N[C@H]1CNC[C@@H]1O)c1ccc(Cl)s1>>CCOC(=O)CN1C[C@H](O)[C@@H](NC(=O)c2ccc(Cl)s2)C1 -US20080306055A1,2,NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1.O=C=Nc1cccc2ccccc12>>O=C(Nc1cccc2ccccc12)NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1 -US20140364433A1,2,COc1ccnc(-c2ccc(C)cc2C(=O)O)n1.C[C@@H]1CCCN[C@@H]1CNc1ccc(C(F)(F)F)cn1>>COc1ccnc(-c2ccc(C)cc2C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(C(F)(F)F)cn2)n1 -US20120226036A1,1,CC(C)(C)C(=O)OCCl.O=C(O)CNc1cccc(C(NCc2ccc(-c3nccs3)cc2)S(=O)(=O)c2ccccn2)n1>>CC(C)(C)C(=O)OCOC(=O)CNc1cccc(C(NCc2ccc(-c3nccs3)cc2)S(=O)(=O)c2ccccn2)n1 -US07220744B2,6,CC(C)(C)OC(=O)N1CCN(c2ncc(S(=O)(=O)c3ccncc3)s2)CC1>>O=S(=O)(c1ccncc1)c1cnc(N2CCNCC2)s1 -US03932498,1,CC[O-].CSc1ccccc1Cl>>CCOc1ccccc1SC -US06982348B2,2,NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1.O=C(O)c1cccc(Oc2ccccc2)c1>>O=C(NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1)c1cccc(Oc2ccccc2)c1 -US07176220B2,6,CCOC(=O)c1cn(CCO[Si](C)(C)C(C)(C)C)c2c(F)cc(Cc3cccc(Cl)c3Cl)cc2c1=O>>CCOC(=O)c1cn(CCO)c2c(F)cc(Cc3cccc(Cl)c3Cl)cc2c1=O -US20140235863A1,4,CC(=O)c1ccc(C=NNC(N)=S)c(N)c1.O=C(CBr)c1ccc(F)cc1>>CC(=O)c1ccc(C=NNc2nc(-c3ccc(F)cc3)cs2)c(N)c1 -US08217043B2,1,COC(=O)c1cc(Cl)cn1N.O=Cc1ccc(Cl)cc1>>COC(=O)c1cc(Cl)cn1N=Cc1ccc(Cl)cc1 -US07935830B2,1,CC1c2cc(Cl)c(O)cc2C2CNCC12.Fc1ccc(CBr)cc1>>CC1c2cc(Cl)c(OCc3ccc(F)cc3)cc2C2CNCC12 -US20100041657A1,2,CC(=O)c1cc(C(C)(C)C)c(O)c(C(=O)O)c1C.Nc1ccc(S(=O)(=O)C(F)(F)F)cc1Cl>>CC(=O)c1cc(C(C)(C)C)c(O)c(C(=O)Nc2ccc(S(=O)(=O)C(F)(F)F)cc2Cl)c1C -US20110060011A1,2,Nc1ccc(-c2coc(-c3ccccc3)n2)cc1.O=C(Cl)c1ccccc1Cl>>O=C(Nc1ccc(-c2coc(-c3ccccc3)n2)cc1)c1ccccc1Cl -US20130338134A1,1,C=O.COc1cc(OC)c(F)c(N2Cc3cnc4c(ccn4COCC[Si](C)(C)C)c3C3(CCNCC3)C2=O)c1F>>COc1cc(OC)c(F)c(N2Cc3cnc4c(ccn4COCC[Si](C)(C)C)c3C3(CCN(C)CC3)C2=O)c1F -US20030060494A1,2,C1CC2CCC(C1)N2.CN(C)C(=O)n1cnc(S(=O)(=O)Cl)n1>>CN(C)C(=O)n1cnc(S(=O)(=O)N2C3CCCC2CC3)n1 -US03988457,1,Cc1ccc2cc(CCl)ccc2c1.c1ccc(N2CCNCC2)nc1>>Cc1ccc2cc(CN3CCN(c4ccccn4)CC3)ccc2c1 -US07700657B2,3,CC(C)(C)[Si](C)(C)Oc1cccc(C=O)c1.CC[Mg+]>>CCC(O)c1cccc(O[Si](C)(C)C(C)(C)C)c1 -US03932661,2,Cc1ccccc1NN.O=C(OC(=O)c1ccccc1)c1ccccc1>>Cc1ccccc1N(N)C(=O)c1ccccc1 -US20050197350A1,1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](N)CC1.Cc1nc(Cl)nc(N(C)C)c1C>>Cc1nc(N[C@@H]2CC[C@H](NC(=O)OC(C)(C)C)CC2)nc(N(C)C)c1C -US08178577B2,2,Nc1ccc(C(F)(F)F)cc1N.O=C(O)CCCCCNC(=O)C=C1c2ccccc2-c2ccccc21>>Nc1cc(C(F)(F)F)ccc1NC(=O)CCCCCNC(=O)C=C1c2ccccc2-c2ccccc21 -US20090221567A1,1,CC(C)(C)OC(=O)N1CCC(C)(N2CCC(=O)CC2)C1.N[C@H]1CCCC[C@@H]1O>>CC(C)(C)OC(=O)N1CCC(C)(N2CCC(N[C@H]3CCCC[C@@H]3O)CC2)C1 -US20140371201A1,9,O=c1ccc2cc(S(=O)(=O)Nc3ccon3)ccc2n1-c1ccc(Cl)cc1Br>>O=c1ccc2cc(S(=O)(=O)Nc3ccon3)ccc2n1-c1ccc(Cl)cc1 -US04709030,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1ccc([C@@H]2CC[C@@H](CC=O)CC2)cc1>>COC=CC[C@@H]1CC[C@@H](c2ccc(C#N)cc2)CC1 -US07148234B2,9,CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCN=[N+]=[N-])c(Cl)c1>>CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCN)c(Cl)c1 -US04171359,7,N#CCc1cc(F)c2c(c1F)OCCO2>>NCCc1cc(F)c2c(c1F)OCCO2 -US08623866B2,2,CC1(C)CCNC1.COC(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1>>Cn1cc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)c(C(=O)N2CCC(C)(C)C2)n1 -US05922717,6,COC(=O)COc1ccc(CC(=O)OCc2ccccc2)cc1>>COC(=O)COc1ccc(CC(=O)O)cc1 -US06040411,6,CC(=O)OCCCCOc1ccc(C(=O)[O-])cc1>>O=C([O-])c1ccc(OCCCCO)cc1 -US20070015812A1,2,Cn1ncc2c1CN[C@H]2C(=O)Nc1ccc(-n2ccccc2=O)cc1F.O=C(O)c1ccc2cc[nH]c2c1>>Cn1ncc2c1CN(C(=O)c1ccc3cc[nH]c3c1)[C@H]2C(=O)Nc1ccc(-n2ccccc2=O)cc1F -US08063234B2,8,CSCc1cccc2c(C3(C4CC4)CCc4cc(F)ccc43)c[nH]c12.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cccc2c(C3(C4CC4)CCc4cc(F)ccc43)c[nH]c12 -US20150023913A1,3,C=CCCCO[C@](C)(C=C)COC(=O)c1ccccc1>>C[C@]1(COC(=O)c2ccccc2)C=CCCCO1 -US20040167182A1,6,CCN1CCC(C(=O)NOC2CCCCO2)(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CC1>>CCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CC1 -US20030055071A1,1,CN(C)C(=O)CNS(C)(=O)=O.O=C(NCc1ccc(F)cc1)c1nc(Br)c2cccnc2c1O>>CN(C)C(=O)CN(c1nc(C(=O)NCc2ccc(F)cc2)c(O)c2ncccc12)S(C)(=O)=O -US06063782,1,CC=CCBr.Cc1cc(C(=O)CCc2ccc(F)cc2F)[nH]c1C>>CC=CCn1c(C(=O)CCc2ccc(F)cc2F)cc(C)c1C -US08133901B2,2,Cc1nc2sccn2c1C(=O)N[C@@H]1CCCNC1.O=C(O)c1ccccc1-c1cccc(Cl)c1>>Cc1nc2sccn2c1C(=O)N[C@@H]1CCCN(C(=O)c2ccccc2-c2cccc(Cl)c2)C1 -US04672063,6,COC(=O)c1ccc(N2C(C)CC(=O)N2CCCN2CCN(c3cc(C)ccn3)CC2)cc1>>Cc1ccnc(N2CCN(CCCN3C(=O)CC(C)N3c3ccc(C(=O)O)cc3)CC2)c1 -US20030212084A1,1,CCCCCCCI.O=C(OCc1ccccc1)C1CCNCC1>>CCCCCCCN1CCC(C(=O)OCc2ccccc2)CC1 -US06018046,6,COc1cc2c(=O)ccn3c4ccc(Br)cc4c(c1)c23>>O=c1ccn2c3ccc(Br)cc3c3cc(O)cc1c32 -US20080318943A1,3,COc1ccc(F)c(B(O)O)c1.Nc1c2c(nc3c(Br)cccc13)CN(C1CCC1)C2=O>>COc1ccc(F)c(-c2cccc3c(N)c4c(nc23)CN(C2CCC2)C4=O)c1 -US07521462B2,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CC(C)CN>>CC(C)CNC1CCN(C(=O)OC(C)(C)C)CC1 -US20020143003A1,1,N#Cc1cc(F)ccc1F.Oc1ccc(Cl)c(Cl)c1>>N#Cc1cc(F)ccc1Oc1ccc(Cl)c(Cl)c1 -US08278325B2,2,CCCCOC(=O)c1nc(Cl)c2ccccc2c1O.CN(C)CCN>>CN(C)CCNC(=O)c1nc(Cl)c2ccccc2c1O -US20100273771A1,1,CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)cc1Cl.CCOC(=O)CCCBr>>CCOC(=O)CCCN1CCc2ccc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)cc2CC1 -US06326369B1,6,COc1c2c(c(OC)c(OC)c1OC)CCC(CCOC(C)=O)CC2>>COc1c2c(c(OC)c(OC)c1OC)CCC(CCO)CC2 -US20070049604A1,1,CC(C)Cc1cc(C=O)n(C(C)(C)C)n1.NCCN1CCN(c2cccc(Cl)c2)CC1>>CC(C)Cc1cc(CNCCN2CCN(c3cccc(Cl)c3)CC2)n(C(C)(C)C)n1 -US06448247B1,6,CC(C)(C)OC(=O)N1CCC2(CC1)c1ccccc1CS2(=O)=O>>O=S1(=O)Cc2ccccc2C12CCNCC2 -US20100286215A1,2,COC(=O)c1cc(C(=O)c2ccc(NC(=O)OCC3c4ccccc4-c4ccccc43)cc2)ccc1N.O=C(Cl)c1ccc(Cl)cc1Cl>>COC(=O)c1cc(C(=O)c2ccc(NC(=O)OCC3c4ccccc4-c4ccccc43)cc2)ccc1NC(=O)c1ccc(Cl)cc1Cl -US20110059942A1,3,CC1(C)OB(c2ccc(O)cc2)OC1(C)C.Cc1cc(Br)ccc1C(=O)O>>Cc1cc(-c2ccc(O)cc2)ccc1C(=O)O -US20110172275A1,2,CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.O=S(=O)(Cl)c1cncc(F)c1>>CN(Cc1cn(S(=O)(=O)c2cncc(F)c2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C -US06313122B1,2,COc1ccc(C(=O)Nc2ccccc2N)cc1.CSc1ccc(C(=O)O)cc1>>COc1ccc(C(=O)Nc2ccccc2NC(=O)c2ccc(SC)cc2)cc1 -US20150018343A1,6,Cc1cc(C)n2nc3c(c2n1)CN(C(=O)OC(C)(C)C)C3>>Cc1cc(C)n2nc3c(c2n1)CNC3 -US04889848,7,N#Cc1cc(-c2ccccc2)c(=O)n2c1-c1sccc1CC2>>NCc1cc(-c2ccccc2)c(=O)n2c1-c1sccc1CC2 -US20030216373A1,2,O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(C2=CCNCC2)c(F)c1.O=S(=O)(Cl)CCCCl>>O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(C2=CCN(S(=O)(=O)CCCCl)CC2)c(F)c1 -US06248765B1,8,OCCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>O=CCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US05208223,1,C=C(CCCCCCCCCCCCCCCC)CC(CO)CO.CCCCCCCCCCCCCCCCBr>>C=C(CCCCCCCCCCCCCCCC)CC(CO)COCCCCCCCCCCCCCCCC -US07285557B2,1,COc1cc([N+](=O)[O-])ccc1OCCBr.FC1CCNC1>>COc1cc([N+](=O)[O-])ccc1OCCN1CCC(F)C1 -US20150197522A1,6,CCOC(=O)Cn1c2ccccc2c2nnc(SC(CC)C(=O)N3c4ccccc4Sc4ccccc43)nc21>>CCC(Sc1nnc2c3ccccc3n(CC(=O)O)c2n1)C(=O)N1c2ccccc2Sc2ccccc21 -US20080275063A1,2,CN.O=[N+]([O-])c1cccc(CS(=O)(=O)Cl)c1>>CNS(=O)(=O)Cc1cccc([N+](=O)[O-])c1 -US08912179B2,4,CC(C)(C)OC(=O)N1CCC(=O)C(Br)C1.NC(N)=S>>CC(C)(C)OC(=O)N1CCc2nc(N)sc2C1 -US20050227978A1,4,CCC=O.Nc1cc(Cl)ccc1C=O>>Cc1cnc2cc(Cl)ccc2c1 -US20090012055A1,2,COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(CC(=O)O)cc3)cc21.c1ccc2c(c1)CCCN2>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(CC(=O)N4CCCc5ccccc54)cc3)cc21 -US08778964B2,6,CC(C)(O)C(CCCC(F)(F)F)NC(=O)OCc1ccccc1>>CC(C)(O)C(N)CCCC(F)(F)F -US20110034455A1,2,CC(C)S(=O)(=O)Cl.O=C(OC1C2CC3CC(C2)CC1C3)N1CCC2(CC1)CNCc1ccccc12>>CC(C)S(=O)(=O)N1Cc2ccccc2C2(CCN(C(=O)OC3C4CC5CC(C4)CC3C5)CC2)C1 -US20060287402A1,2,CC(C)C[C@H](NC(c1ccc(C(=O)O)cc1)C(F)(F)F)C(=O)NCC#N.CN1CCNCC1>>CC(C)C[C@H](NC(c1ccc(C(=O)N2CCN(C)CC2)cc1)C(F)(F)F)C(=O)NCC#N -US20130281438A1,2,CC(=O)OC(C)=O.Nc1cccc2c1OCCO2>>CC(=O)Nc1cccc2c1OCCO2 -US20050245527A1,1,CI.O=c1cncc(CCN2CCC(COc3ccccc3F)CC2)[nH]1>>Cn1c(CCN2CCC(COc3ccccc3F)CC2)cncc1=O -US20150175557A1,9,CC1(C)CC(=O)CCC1O.NO>>CC1(C)C/C(=N/O)CCC1O -US20100278733A1,1,CI.Nc1ccc(C=CC(=O)c2ccc(Br)s2)cc1>>CNc1ccc(C=CC(=O)c2ccc(Br)s2)cc1 -US07183298B2,2,COC(=O)C=Cc1cccc(S(=O)(=O)Cl)c1.COc1cccc(N)c1>>COC(=O)C=Cc1cccc(S(=O)(=O)Nc2cccc(OC)c2)c1 -US06391887B1,7,Cc1ccc2[nH]c(=O)c3c(c2c1)CCC3>>Cc1ccc2c(c1)C1CCCC1C(=O)N2 -US20090149501A1,3,CC1(C)C(C(=O)Cl)C1(C)C.O=[N+]([O-])c1cccc2[nH]ccc12>>CC1(C)C(C(=O)c2c[nH]c3cccc([N+](=O)[O-])c23)C1(C)C -US07803822B2,2,CCNC(=O)c1ccc(-n2nnc(C(=O)O)c2Cc2ccccc2)cc1.NC1CC1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2Cc2ccccc2)cc1 -US20140155389A1,7,CCOC(=O)c1cc(Cl)nc(Cl)c1>>OCc1cc(Cl)nc(Cl)c1 -US20150126490A1,3,Nc1ncc(C2CCC3(CC2)OCCO3)nc1Br.O=C(NCc1ccccc1)c1ccc(B(O)O)cc1F>>Nc1ncc(C2CCC3(CC2)OCCO3)nc1-c1ccc(C(=O)NCc2ccccc2)c(F)c1 -US20060160864A1,6,CCCCOCCOc1ccc(-c2ccc(N(C)CCOC)c(/C=C/C(=O)OCC)c2)cc1>>CCCCOCCOc1ccc(-c2ccc(N(C)CCOC)c(/C=C/C(=O)O)c2)cc1 -US20080227980A1,2,CCN1CCNCC1.C[C@@H](Nc1ncnc2[nH]c(-c3ccc(C(=O)O)cc3)cc12)c1ccccc1>>CCN1CCN(C(=O)c2ccc(-c3cc4c(N[C@H](C)c5ccccc5)ncnc4[nH]3)cc2)CC1 -US07812022B2,6,O=C(Nc1cccc(-c2nn3cccc(F)c3c2-c2ccnc(Cl)n2)c1)C(F)(F)F>>Nc1cccc(-c2nn3cccc(F)c3c2-c2ccnc(Cl)n2)c1 -US20100113438A1,1,CC(=O)c1ccc(N2CCNCC2)cc1.O=Cc1ccccc1>>CC(=O)c1ccc(N2CCN(Cc3ccccc3)CC2)cc1 -US08772323B2,3,CCOC(=O)/C=C/I.O=Cc1ccc2nc(-c3cccs3)oc2c1>>CCOC(=O)/C=C/C(O)c1ccc2nc(-c3cccs3)oc2c1 -US20120283238A1,6,CN(C)C1CCC(N(CCO)C(=O)OC(C)(C)C)CC1>>CN(C)C1CCC(NCCO)CC1 -US20100113782A1,1,CC(C)(C)OC(=O)c1ccc(Br)cc1.CC(C)(C)c1cccc(NC(=O)c2ccc(N3CCNCC3)nc2)c1>>CC(C)(C)OC(=O)c1ccc(N2CCN(c3ccc(C(=O)Nc4cccc(C(C)(C)C)c4)cn3)CC2)cc1 -US20110275622A1,8,COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5cccc(-c6ccc(CCCCO)cc6)c5)c4)cc23)c1>>COc1cccc(Nc2c(C(N)=O)cnc3c(C)cc(S(=O)(=O)c4cccc(C(=O)Nc5cccc(-c6ccc(CCCC=O)cc6)c5)c4)cc23)c1 -US20100204196A1,1,CCN(C)CC(=O)N1CCc2cc(OC)c(N)cc21.Cc1ccc(S(=O)(=O)n2ccc3c2nc(Cl)n2c(=O)c4c(F)cccc4nc32)cc1>>CCN(C)CC(=O)N1CCc2cc(OC)c(Nc3nc4c(ccn4S(=O)(=O)c4ccc(C)cc4)c4nc5cccc(F)c5c(=O)n34)cc21 -US20140349987A1,1,CC(C)(C)c1cc(Br)cc(C(C)(C)O)c1.CI>>COC(C)(C)c1cc(Br)cc(C(C)(C)C)c1 -US20070225349A1,3,CON(C)C(=O)c1cccc(C(F)(F)F)c1F.COc1ccc([Mg+])cc1>>COc1ccc(C(=O)c2cccc(C(F)(F)F)c2F)cc1 -US20140303161A1,6,CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc21>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1F)nn2C[C@@H]1CC(F)(F)CN1 -US20110003809A1,2,CCCS(=O)(=O)Cl.Nc1ccc(Cl)c(C(=O)O)c1Cl>>CCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)O)c1Cl -US05283336,7,O=[N+]([O-])c1ccc2c(c1)NCCC2>>Nc1ccc2c(c1)NCCC2 -US05273993,7,O=C(O)CCOc1ccccc1>>OCCCOc1ccccc1 -US08815919B2,1,COCCN.N#Cc1ccc(CBr)cc1>>COCCNCc1ccc(C#N)cc1 -US04612321,2,CCOC(=O)CC(=O)Cl.COc1ccc(-c2nc(N)sc2-c2cccnc2)cc1>>CCOC(=O)CC(=O)Nc1nc(-c2ccc(OC)cc2)c(-c2cccnc2)s1 -US20080021024A1,1,COC(=O)c1cc(CBr)ncn1.Cc1c(C(=O)OC(C)(C)C)ccc2c1CCC2NCC(=O)OC(C)(C)C>>COC(=O)c1cc(CN(CC(=O)OC(C)(C)C)C2CCc3c2ccc(C(=O)OC(C)(C)C)c3C)ncn1 -US08759386B2,2,Cc1c(C(=O)O)oc2c(Cl)cccc12.Cc1nn(Cc2ccc(N)cc2)c(C)c1CC(=O)OC(C)(C)C>>Cc1nn(Cc2ccc(NC(=O)c3oc4c(Cl)cccc4c3C)cc2)c(C)c1CC(=O)OC(C)(C)C -US20130072470A1,2,C[C@@H]1C[C@H](N)C[C@@H]1c1cnc2cnc3[nH]ccc3n12.O=C(O)c1cccnn1>>C[C@H]1C[C@H](NC(=O)c2cccnn2)C[C@@H]1c1cnc2cnc3[nH]ccc3n12 -US20130345439A1,1,C=O.Fc1ccc(C23CNCC2C3)c2ccccc12>>CN1CC2CC2(c2ccc(F)c3ccccc23)C1 -US20100029710A1,3,CCc1nc2c(C)cc(CC(C)=O)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21.C[Mg+]>>CCc1nc2c(C)cc(CC(C)(C)O)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21 -US20140163016A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCCN1CCSc2cc([N+](=O)[O-])ccc21>>CN(CCN1CCSc2cc([N+](=O)[O-])ccc21)C(=O)OC(C)(C)C -US07384945B2,6,CC(C)(C)OC(=O)N1CCN(c2cc3c(cc2F)nc(COc2ccccc2)n3Cc2ccc(Cl)cc2)CC1>>Fc1cc2nc(COc3ccccc3)n(Cc3ccc(Cl)cc3)c2cc1N1CCNCC1 -US06613770B1,2,C[C@H](N)C(C)(C)C.O=C(O)c1c(CN2CCC(N3CCCCC3)CC2)c(-c2ccccc2)nc2ccccc12>>C[C@H](NC(=O)c1c(CN2CCC(N3CCCCC3)CC2)c(-c2ccccc2)nc2ccccc12)C(C)(C)C -US20100227872A1,3,CCOc1ccc(OC(F)(F)F)c(B(O)O)c1.Cc1nocc1C(=O)Nc1cnc(Cl)c(N)n1>>CCOc1ccc(OC(F)(F)F)c(-c2ncc(NC(=O)c3conc3C)nc2N)c1 -US20060148858A1,7,CCCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1/C=C/C(=O)OCC>>CCCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCC(=O)OCC -US20130261101A1,7,CC(=O)c1cc(Cl)c(C)c(C(=O)O)c1OCCNC(=O)OC(C)(C)C>>Cc1c(Cl)cc(C(C)O)c(OCCNC(=O)OC(C)(C)C)c1C(=O)O -US20070179178A1,2,Cc1onc(-c2ccccc2)c1-c1cn2cc(N)ccc2n1.O=C(O)CC1CC1>>Cc1onc(-c2ccccc2)c1-c1cn2cc(NC(=O)CC3CC3)ccc2n1 -US20100197692A1,6,CCOC(=O)Cn1nnc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc21>>O=C(O)Cn1nnc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc21 -US20130072473A1,2,NC(=O)c1c(N)sc2c1CCCC2.O=C(Cl)c1ccccc1Cl>>NC(=O)c1c(NC(=O)c2ccccc2Cl)sc2c1CCCC2 -US05670503,7,CC(=O)OCC(=O)N1NCCn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c21>>O=C(CO)N1NCCn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c21 -US20060183909A1,7,COC(=O)c1cc(O)c2cc(C)cc([N+](=O)[O-])c2n1>>COC(=O)c1cc(O)c2cc(C)cc(N)c2n1 -US20090221600A1,6,CSc1ncc2cc(-c3ccccc3C)c(=O)n([C@H]3CCN(C(=O)OC(C)(C)C)C3)c2n1>>CSc1ncc2cc(-c3ccccc3C)c(=O)n([C@H]3CCNC3)c2n1 -US05378728,2,CC(C)(C)C(=O)c1ccc(C(=O)Cl)cc1.NC(=O)CCc1ccccc1>>CC(C)(C)C(=O)c1ccc(C(=O)NC(=O)CCc2ccccc2)cc1 -US08604038B2,6,COC(=O)c1ccc(C[C@@H]2CC[C@H]([C@H](O[Si](C)(C)C(C)(C)C)c3cccnc3)N2C(=O)OC(C)(C)C)cc1>>COC(=O)c1ccc(C[C@@H]2CC[C@H]([C@H](O)c3cccnc3)N2C(=O)OC(C)(C)C)cc1 -US20050197337A1,1,CNOC.O=C(Cl)C1CC1>>CON(C)C(=O)C1CC1 -US20130345245A1,6,Cn1c(-c2nc(N)ncc2C#Cc2cccc(NC(=O)Nc3ccc(C(F)(F)F)cc3)c2)cc2c1CCN(C(=O)OC(C)(C)C)C2=O>>Cn1c(-c2nc(N)ncc2C#Cc2cccc(NC(=O)Nc3ccc(C(F)(F)F)cc3)c2)cc2c1CCNC2=O -US20150057260A1,1,CCOC(=O)c1nc(Cl)ncc1F.NC1CC1>>CCOC(=O)c1nc(Cl)ncc1NC1CC1 -US06911458B2,6,CCOC(=O)c1[nH]c(C)cc1C>>Cc1cc(C)c(C(=O)O)[nH]1 -US20100144706A1,1,CNC.O=Cc1ccc([N+](=O)[O-])cc1>>CN(C)Cc1ccc([N+](=O)[O-])cc1 -US05021420,1,CNC.O=S1(=O)c2cccc3cccc(c23)N1CC(Br)CN1CCN(c2ccc(F)cc2)CC1>>CN(C)C(CN1CCN(c2ccc(F)cc2)CC1)CN1c2cccc3cccc(c23)S1(=O)=O -US20110021479A1,3,CCOC(=O)c1c[nH]c2c(Cl)ncnc12.COc1ccc(B2OC(C)(C)C(C)(C)O2)c(OCC2CC2)c1>>CCOC(=O)c1c[nH]c2c(-c3ccc(OC)cc3OCC3CC3)ncnc12 -US20090062280A1,1,CC(C)CCI.NCCCO>>CC(C)CCNCCCO -US20130225552A1,1,C1COCCN1.Clc1ncnc2c1ncn2[C@@H]1C[C@@H](Nc2ncc3ccccc3n2)C1>>c1ccc2nc(N[C@@H]3C[C@@H](n4cnc5c(N6CCOCC6)ncnc54)C3)ncc2c1 -US20060100245A1,2,CC(C)(C)c1ccc(N)cc1.O=C(O)c1ccc(Br)cn1>>CC(C)(C)c1ccc(NC(=O)c2ccc(Br)cn2)cc1 -US09102614B2,7,Cc1c(C(OC(C)(C)C)C(=O)O)c(-c2ccc(Cl)cc2)c2ccccc2c1C#CCN(C)C>>Cc1c(C(OC(C)(C)C)C(=O)O)c(-c2ccc(Cl)cc2)c2ccccc2c1CCCN(C)C -US20150148340A1,1,CCOC(=O)c1cn(-c2cc3[nH]c(=O)[nH]c3cc2C)c(=O)[nH]c1=O.Cc1c(CBr)cccc1C(F)(F)F>>CCOC(=O)c1cn(-c2cc3[nH]c(=O)[nH]c3cc2C)c(=O)n(Cc2cccc(C(F)(F)F)c2C)c1=O -US06436691B1,6,Cc1cc(Oc2ccc(C(=O)N[C@@H](C)C(=O)OC(C)(C)C)cc2)ccc1N(CCCl)CCCl>>Cc1cc(Oc2ccc(C(=O)N[C@@H](C)C(=O)O)cc2)ccc1N(CCCl)CCCl -US20150148377A1,6,COc1ncc(-c2ccnc3ccc(O[C@H]4CCN(C(=O)OC(C)(C)C)C4)cc23)cc1Cl>>COc1ncc(-c2ccnc3ccc(O[C@H]4CCNC4)cc23)cc1Cl -US07906532B2,6,CCOC(=O)c1nn(C(C)C)c2ccc(F)cc12>>CC(C)n1nc(C(=O)O)c2cc(F)ccc21 -US20100022550A1,7,CC(C)C(=O)NC1CCc2c(c3cc(Cl)ccc3n2Cc2ccccc2[N+](=O)[O-])C1>>CC(C)C(=O)NC1CCc2c(c3cc(Cl)ccc3n2Cc2ccccc2N)C1 -US06617325B1,2,NC1CCN(Cc2ccccc2)CC1.O=C(O)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(NC1CCN(Cc2ccccc2)CC1)c1ccccc1-c1ccc(C(F)(F)F)cc1 -US20080293940A1,2,CC(C)(C)OC(=O)N1CCN(Cc2ccc(C(=O)O)cc2C(F)(F)F)CC1.Cc1ccc(N)cc1Nc1nccc(-c2cncc(Br)c2)n1>>Cc1ccc(NC(=O)c2ccc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(C(F)(F)F)c2)cc1Nc1nccc(-c2cncc(Br)c2)n1 -US20140275245A1,7,CC(=O)NC12CC(OC(C)=O)(C1)C2>>CC(=O)NC12CC(O)(C1)C2 -US05578620,9,[N-]=[N+]=NCC(O)COCc1ccccc1>>NCC(O)COCc1ccccc1 -US08927585B2,9,CC(C)(C)CN1CC2(CCCC(C)(CN=[N+]=[N-])C2)OC1=O>>CC(C)(C)CN1CC2(CCCC(C)(CN)C2)OC1=O -US20050143452A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Cc1ccccc1-c1c(F)ccc2c1OC(CO)C2>>Cc1ccc(S(=O)(=O)OCC2Cc3ccc(F)c(-c4ccccc4C)c3O2)cc1 -US04053484,6,CC(=O)NC1CCC(=O)c2sccc21>>NC1CCC(=O)c2sccc21 -US20150216175A1,2,CCn1c(C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)cc2cc(C(=O)O)c(C)nc21.NC1CC1>>CCn1c(C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)cc2cc(C(=O)NC3CC3)c(C)nc21 -US05820944,2,O=C=NCc1ccccc1.O=[N+]([O-])c1ccccc1CO>>O=C(NCc1ccccc1)OCc1ccccc1[N+](=O)[O-] -US20100048636A1,2,CC(C)(C)OC(=O)N1[C@@H](C[C@H](CO)CCC(=O)OC2CCCCC2)COC1(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](CCC(=O)OC2CCCCC2)C[C@H]2COC(C)(C)N2C(=O)OC(C)(C)C)cc1 -US20080103141A1,1,CC(C)(C)OC(=O)N1CCC(COc2ncc(-c3ccc(CO)cc3)cn2)CC1.O=C1CCC(=O)N1>>CC(C)(C)OC(=O)N1CCC(COc2ncc(-c3ccc(CN4C(=O)CCC4=O)cc3)cn2)CC1 -US06313117B1,1,CC(C)(C)CC=O.OC1CCNC1>>CC(C)(C)CCN1CCC(O)C1 -US20070249612A1,1,CC(C)(C)C(=O)CBr.CCOC(=O)c1nn(C(C)(C)C)c(=O)[nH]1>>CCOC(=O)c1nn(C(C)(C)C)c(=O)n1CC(=O)C(C)(C)C -US08507472B2,6,Fc1ccc(-c2nn3c(c2-c2ccnc(NCc4ccccc4)c2)CCCC3)cc1>>Nc1cc(-c2c(-c3ccc(F)cc3)nn3c2CCCC3)ccn1 -US04447439,1,CI.CN1CCC(OC(=O)C(c2noc3ccccc23)N2CCCCC2)CC1>>C[N+]1(C)CCC(OC(=O)C(c2noc3ccccc23)N2CCCCC2)CC1 -US20120196848A1,3,CC(C)(C)OC(=O)N1CCOc2c(Br)csc2C1.OB(O)c1ccoc1>>CC(C)(C)OC(=O)N1CCOc2c(-c3ccoc3)csc2C1 -US08940756B2,9,Cn1c(=O)c(-c2cc(N)c(F)cc2F)cc2cnc(Cl)cc21>>Cn1c(=O)c(-c2cc(N)c(F)cc2F)cc2cnccc21 -US20090239860A1,7,CC(=O)c1cccc(C(=O)Nc2c(C(N)=O)oc3ccc(F)cc23)c1>>CC(O)c1cccc(C(=O)Nc2c(C(N)=O)oc3ccc(F)cc23)c1 -US20120149721A1,2,CC(=O)Cl.Cc1[nH]c2c(-c3ccc(F)cc3OCC3CC3)ncnc2c1C(=O)N[C@H]1CC[C@@H](N)CC1>>CC(=O)N[C@@H]1CC[C@H](NC(=O)c2c(C)[nH]c3c(-c4ccc(F)cc4OCC4CC4)ncnc23)CC1 -US20050101644A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=C1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1>>CC(C)(C)OC(=O)N1CCN(C2CCN(Cc3cc(Br)ccc3OCc3ccc(Cl)cc3)CC2)CC1 -US20150203517A1,2,COCCOCCOCCNC(=O)CNCC(=O)NCCOCCOCCOC.O=C(O)CCC(=O)NC(=O)Cc1ccc(CCCCc2ccccc2)cc1>>COCCOCCOCCNC(=O)CN(CC(=O)NCCOCCOCCOC)C(=O)CCC(=O)NC(=O)Cc1ccc(CCCCc2ccccc2)cc1 -US20150080393A1,1,COC(=O)C1CC2(CCNCC2)CCN1.Cc1ccn(-c2cc(Cl)ccc2[C@@H](Oc2cc(Cl)nc(N)n2)C(F)(F)F)n1>>COC(=O)C1CC2(CCN1)CCN(c1cc(O[C@H](c3ccc(Cl)cc3-n3ccc(C)n3)C(F)(F)F)nc(N)n1)CC2 -US05686433,3,CC(C)c1cc(-c2ccccc2)nc(-c2ccc(F)cc2)c1/C=C/C=O.COC(=O)CC(C)=O>>COC(=O)CC(=O)CC(O)/C=C/c1c(C(C)C)cc(-c2ccccc2)nc1-c1ccc(F)cc1 -US06300344B1,6,COc1cccc2c1CCCC2NC(C)c1nc(-c2ccccc2)c(-c2ccccc2)o1>>CC(NC1CCCc2c(O)cccc21)c1nc(-c2ccccc2)c(-c2ccccc2)o1 -US04677129,1,C=CCBr.O=C1NC(=O)C2(c3ccc([N+](=O)[O-])cc3)CC1C2>>C=CCN1C(=O)C2CC(c3ccc([N+](=O)[O-])cc3)(C2)C1=O -US06326386B1,2,CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)O)c1)c1ccncc1.O=S(=O)(F)CCNc1ccccc1>>CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)N(CCS(=O)(=O)F)c2ccccc2)c1)c1ccncc1 -US04681593,3,C#Cc1ccccc1.O=Cc1cccc(Oc2ccccc2)c1>>OC(C#Cc1ccccc1)c1cccc(Oc2ccccc2)c1 -US07618978B2,6,CCCN(C)C(=O)c1cc(C=C(F)F)cc(C(=O)OCC)c1>>CCCN(C)C(=O)c1cc(C=C(F)F)cc(C(=O)O)c1 -US20130109682A1,7,O=C1CC(c2ccncc2[N+](=O)[O-])OC2(CC2)C1>>O=[N+]([O-])c1cnccc1[C@H]1C[C@@H](O)CC2(CC2)O1 -US20080039460A1,8,COCCC(=O)Nc1cccc(CO)c1>>COCCC(=O)Nc1cccc(C=O)c1 -US07863293B2,1,CC(=O)c1nccs1.CC(C)(C)OC(=O)NCCCCN>>CC(NCCCCNC(=O)OC(C)(C)C)c1nccs1 -US08003649B2,1,Cn1c(C=O)cc2ccccc21.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>Cn1c(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc2ccccc21 -US20150025065A1,1,Brc1cccc(I)c1.CS(C)(=N)=O>>CS(C)(=O)=Nc1cccc(Br)c1 -US04264617,3,COc1ccccc1C=O.O=C1CNC(=O)N1>>COc1ccccc1C=C1NC(=O)NC1=O -US20120142681A1,1,CC(=O)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1.NNC(=O)Nc1ccc(Cl)cc1>>C/C(=N\NC(=O)Nc1ccc(Cl)cc1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 -US20100168080A1,2,Nc1cccc(F)c1.O=C(O)CCN1CCCOC(Cc2ccc(F)cc2)C1>>O=C(CCN1CCCOC(Cc2ccc(F)cc2)C1)Nc1cccc(F)c1 -US07208494B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]1CNCc2cc3ccc(Br)nc3n21>>C[C@@H]1CN(C(=O)OC(C)(C)C)Cc2cc3ccc(Br)nc3n21 -US05519024,6,CCOC(=O)c1cn(Cc2nccs2)c2c(F)c(F)c(F)cc2c1=O>>O=C(O)c1cn(Cc2nccs2)c2c(F)c(F)c(F)cc2c1=O -US20130040930A1,2,CS(=O)(=O)c1cc(N2CCCS2(=O)=O)ccc1C(=O)O.Cc1ccc(N2CCNCC2)c(C)n1>>Cc1ccc(N2CCN(C(=O)c3ccc(N4CCCS4(=O)=O)cc3S(C)(=O)=O)CC2)c(C)n1 -US08436008B2,2,CC1Cc2ccc(-c3ccc(C(=O)O)nc3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1.CN1CCNCC1>>CC1Cc2ccc(-c3ccc(C(=O)N4CCN(C)CC4)nc3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1 -US20140005221A1,1,COC(=O)c1cnc2cc[nH]c2c1.Cc1cccc(C)c1CCl>>COC(=O)c1cnc2ccn(Cc3c(C)cccc3C)c2c1 -US08084620B2,2,Cc1c(N)cccc1Br.O=C(O)c1ncc[nH]1>>Cc1c(Br)cccc1NC(=O)c1ncc[nH]1 -US07495007B2,2,C=C(C)C1N(CC(=O)F)C(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12.CS(=O)(=O)N1CCC(N)CC1>>C=C(C)C1N(CC(=O)NC2CCN(S(C)(=O)=O)CC2)C(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12 -US20110201625A1,6,CN(CCNC(=O)c1nc(Cl)c(N)nc1N)C(=O)OC(C)(C)C>>CNCCNC(=O)c1nc(Cl)c(N)nc1N -US20080167307A1,6,CCC(=O)Nc1ccc(CN(CCc2csc(SC(C)(C)C(=O)OC(C)(C)C)n2)c2ncc(CC)cn2)cc1>>CCC(=O)Nc1ccc(CN(CCc2csc(SC(C)(C)C(=O)O)n2)c2ncc(CC)cn2)cc1 -US20110257100A1,2,CS(=O)(=O)Cl.O=C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CO)cn4)sc23)c(F)c1)NC1CC1>>CS(=O)(=O)OCc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1 -US09073940B2,1,C1COCCN1.CC(C)(Cl)c1ccc(I)cc1>>CC(C)(c1ccc(I)cc1)N1CCOCC1 -US05612377,1,CCCC(Br)CC.O=C(NOCc1ccccc1)Nc1ccccc1>>CCCC(CC)N(OCc1ccccc1)C(=O)Nc1ccccc1 -US08501992B2,2,Fc1ccc(CCNCc2cccc(CSCCc3ccccc3)c2)cc1.O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1O>>O=S(=O)(c1cc(Cl)cc(Cl)c1O)N(CCc1ccc(F)cc1)Cc1cccc(CSCCc2ccccc2)c1 -US05242936,1,C=CC(=O)OCCCC.CC(C)(C)c1ccc(O)cc1>>CCCCOC(=O)CCOc1ccc(C(C)(C)C)cc1 -US06071901,1,CCOC(=O)C1CNCCN1.OCCCN1c2ccccc2CCc2ccccc21>>CCOC(=O)C1CN(CCCN2c3ccccc3CCc3ccccc32)CCN1 -US07696223B2,3,CCOC(=O)c1nc(Br)c2sc(-c3ccccc3)nc2c1O.C[Sn](C)(C)C>>CCOC(=O)c1nc(C)c2sc(-c3ccccc3)nc2c1O -US20130040931A1,7,Nc1nc2ccc(-c3ccccc3C(=O)C3CCOCC3)cc2cc1N1CCOCC1>>Nc1nc2ccc(-c3ccccc3C(O)C3CCOCC3)cc2cc1N1CCOCC1 -US06740670B2,6,CCCCCN(CCCCC)C(=O)c1cc(C=O)ccc1OC>>CCCCCN(CCCCC)C(=O)c1cc(C=O)ccc1O -US08957070B2,2,CCOC(=O)c1cc2ccc(Cl)c(N)c2[nH]1.O=S(=O)(Cl)c1cccs1>>CCOC(=O)c1cc2ccc(Cl)c(NS(=O)(=O)c3cccs3)c2[nH]1 -US06417203B1,1,Cc1c(Cl)nc(Cl)c(=O)n1CC(=O)OCc1ccccc1.NC[C@@H]1COCCN1Cc1ccccc1>>Cc1c(Cl)nc(NC[C@@H]2COCCN2Cc2ccccc2)c(=O)n1CC(=O)OCc1ccccc1 -US20050245540A1,6,CC(C)(C)OC(=O)N1CCC(c2cn(Cc3ccc(C(C)(C)C)cc3)c3cc(OCc4ccc(C(C)(C)C)cc4)ccc23)CC1>>CC(C)(C)c1ccc(COc2ccc3c(C4CCNCC4)cn(Cc4ccc(C(C)(C)C)cc4)c3c2)cc1 -US20100035917A1,2,COc1cccc(N)c1.O=C(O)Cc1cc2c(Br)ccnc2[nH]1>>COc1cccc(NC(=O)Cc2cc3c(Br)ccnc3[nH]2)c1 -US20040167128A1,2,Nc1ccc2ccccc2c1C(=O)O.O=S(=O)(Cl)c1ccccc1>>O=C(O)c1c(NS(=O)(=O)c2ccccc2)ccc2ccccc12 -US20050107377A1,1,BrCCCOc1ccccc1.C1CCNCC1>>c1ccc(OCCCN2CCCCC2)cc1 -US20070249670A1,2,COC(=O)C1(NC(=O)c2cc3ccccc3cc2N)CCC(=O)CC1.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)C1(NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(C)cc(C)cc2C)CCC(=O)CC1 -US20070149570A1,2,CC(=O)N1CCC(C(=O)O)CC1.FC(F)(F)Oc1ccc(-c2ccc(Cl)cc2Cl)cc1CN[C@H]1CCNC[C@H]1c1ccccc1>>CC(=O)N1CCC(C(=O)N2CC[C@H](NCc3cc(-c4ccc(Cl)cc4Cl)ccc3OC(F)(F)F)[C@H](c3ccccc3)C2)CC1 -US04889858,10,CCOC(=O)c1cccc(F)c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1cccc(F)c1CBr -US20110190269A1,1,COc1cc(Br)ccc1-n1cnc(C)c1.Cc1cc(-c2ccc(F)c(C)c2)c2nc(N)nn2c1>>COc1cc(Nc2nc3c(-c4ccc(F)c(C)c4)cc(C)cn3n2)ccc1-n1cnc(C)c1 -US20140206682A1,2,Cc1ccc(C(=O)O)cc1NC(=O)c1cnc2ccccn12.N[C@@H]1c2ccccc2C[C@@H]1O>>Cc1ccc(C(=O)N[C@@H]2c3ccccc3C[C@@H]2O)cc1NC(=O)c1cnc2ccccn12 -US20110288067A1,3,C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12)C(C)(C)C.O=Cc1ccc(B(O)O)s1>>C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3ccc(C=O)s3)nc12)C(C)(C)C -US20090093484A1,3,C#CCN1CCOCC1.COC(=O)COc1ccc(OC/C=C(\c2ccc(I)cc2)c2ccc(C3CC3)cc2)cc1C>>COC(=O)COc1ccc(OC/C=C(\c2ccc(C#CCN3CCOCC3)cc2)c2ccc(C3CC3)cc2)cc1C -US08916593B2,1,CC(O)c1cc(F)ccc1Cl.Nc1ncc(Br)cc1O>>CC(Oc1cc(Br)cnc1N)c1cc(F)ccc1Cl -US04200588,4,ClCCOCCCl.Nc1ccc(OC23CC4CC(CC(C4)C2)C3)cc1>>c1cc(N2CCOCC2)ccc1OC12CC3CC(CC(C3)C1)C2 -US08383654B2,1,CC(C)(C)SCc1cc(NC(=O)C(C)(C)C)ccc1CBr.N#CCc1cn[nH]c1>>CC(C)(C)SCc1cc(NC(=O)C(C)(C)C)ccc1Cn1cc(CC#N)cn1 -US20070299068A1,1,CCn1c(-c2ccc(NC(=O)C3CC3)cc2)c(C#N)c2ccc(O)cc21.ClCCBr>>CCn1c(-c2ccc(NC(=O)C3CC3)cc2)c(C#N)c2ccc(OCCCl)cc21 -US20100184831A1,1,CCCCCCCCC=CCCCCCCCCOCC(CN(C)C)OCCCCCCCCC=CCCCCCCCC.O=C(CCO)CCC(=O)CCOC(=O)CCCCBr>>CCCCCCCCC=CCCCCCCCCOCC(C[N+](C)(C)CCCCC(=O)OCCC(=O)CCC(=O)CCO)OCCCCCCCCC=CCCCCCCCC -US20090111808A1,1,COC(=O)c1ccc(OCCCCl)cc1.C[C@@H]1CNC[C@@H](C)C1>>COC(=O)c1ccc(OCCCN2C[C@@H](C)C[C@H](C)C2)cc1 -US04207337,2,COC(=O)CC(C)C(=O)N[C@@H](C)C(=O)O.NO>>CC(CC(=O)NO)C(=O)N[C@@H](C)C(=O)O -US20040266839A1,2,COc1ccc(CN)cc1.Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)O)cc3)c2)o1>>COc1ccc(CNC(=O)c2ccc(-c3cc(-c4nnc(C)o4)ccc3C)cc2)cc1 -US20090198063A1,1,COc1cnc2ccc(=O)n(CCN3CCC(N)CC3)c2c1.COc1ncc(C=O)cc1F>>COc1cnc2ccc(=O)n(CCN3CCC(NCc4cnc(OC)c(F)c4)CC3)c2c1 -US04766131,2,CC(=O)Cl.COc1cccc(CCN)c1>>COc1cccc(CCNC(C)=O)c1 -US03991053,1,CC(=O)[O-].CC(=O)c1c(CBr)[n+]([O-])c2ccccc2[n+]1[O-]>>CC(=O)OCc1c(C(C)=O)[n+]([O-])c2ccccc2[n+]1[O-] -US20110071175A1,6,COC(=O)Cn1c(C)c(Cc2cccnc2S(=O)(=O)Nc2ccccc2)c2cc(F)ccc21>>Cc1c(Cc2cccnc2S(=O)(=O)Nc2ccccc2)c2cc(F)ccc2n1CC(=O)O -US03988143,1,CCCN1CCC(O)N(c2nnc(SC)s2)C1=O.CCCO>>CCCOC1CCN(CCC)C(=O)N1c1nnc(SC)s1 -US20130303538A1,2,COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1.O=C(O)c1cccc(C(F)(F)F)c1>>COC(=O)N1CC[C@@H]2[C@H]1CCC[C@]2(C#Cc1cccc(C)c1)OC(=O)c1cccc(C(F)(F)F)c1 -US20050002865A1,1,CCCCCCCCCCCCCCCCI.C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O>>CCCCCCCCCCCCCCCCSC[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O -US20100331328A1,6,CCOC(=O)COc1nc(Nc2cc3ccccc3cn2)cnc1C#N>>N#Cc1ncc(Nc2cc3ccccc3cn2)nc1OCC(=O)O -US07304062B2,2,CO.O=C(O)CCCc1ccc(I)cc1>>COC(=O)CCCc1ccc(I)cc1 -US20120256172A1,3,Brc1cc2ccccc2c2ccccc12.O=Cc1ccccc1B(O)O>>O=Cc1ccccc1-c1cc2ccccc2c2ccccc12 -US20090029975A1,2,CCCO.CS(=O)(=O)c1cc(CCC(=O)O)nc(-c2nc(=O)c3ccc(Cl)cc3s2)c1>>CCCOC(=O)CCc1cc(S(C)(=O)=O)cc(-c2nc(=O)c3ccc(Cl)cc3s2)n1 -US08536165B2,1,BrC1CC1.Oc1cccc(Br)c1>>Brc1cccc(OC2CC2)c1 -US07332511B2,1,CI.O=c1cnc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2[nH]1>>Cn1c(=O)cnc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc21 -US06831081B2,1,Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)sc21.OC(c1ccccn1)C1CCCN1>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCC[C@@H]3[C@@H](O)c3ccccn3)sc21 -US05578634,1,CCOC(=O)Cc1c(C)[nH]c2ccc(OC)cc12.ClCc1ccc(Cl)cc1>>CCOC(=O)Cc1c(C)n(Cc2ccc(Cl)cc2)c2ccc(OC)cc12 -US20100292214A1,2,COc1ccc(S(=O)(=O)Cl)cc1.C[C@@H](COC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1)N(Cc1ccccc1)Cc1ccccc1>>COc1ccc(S(=O)(=O)n2c(=O)n(C3CCN(C(=O)OC[C@H](C)N(Cc4ccccc4)Cc4ccccc4)CC3)c3ccccc32)cc1 -US07939537B2,2,CNc1cccn2c(=O)c(O)c(C(=O)NCc3ccc(F)cc3)nc12.CS(=O)(=O)CC(=O)Cl>>CN(C(=O)CS(C)(=O)=O)c1cccn2c(=O)c(O)c(C(=O)NCc3ccc(F)cc3)nc12 -US04026902,2,CCOC(=O)c1ccc(N)cc1.Cc1cc(C(=O)Cl)on1>>CCOC(=O)c1ccc(NC(=O)c2cc(C)no2)cc1 -US07759385B2,2,CN(C)C1(c2ccccc2)CCC(=CC(=O)O)CC1.c1ccc2c(C3CCCNC3)c[nH]c2c1>>CN(C)C1(c2ccccc2)CCC(=CC(=O)N2CCCC(c3c[nH]c4ccccc34)C2)CC1 -US20050107334A1,1,CCCC(Cl)OOC(=O)SCC.O=C(O)C1CCCC1>>CCCC(OOC(=O)SCC)OC(=O)C1CCCC1 -US20150133512A1,6,C=CC[C@@H](C(=O)OCC)c1ccc(-c2ccc(-n3nnc(C)c3NC(=O)OC(C)c3ccccc3)cc2)cc1>>C=CC[C@@H](C(=O)O)c1ccc(-c2ccc(-n3nnc(C)c3NC(=O)OC(C)c3ccccc3)cc2)cc1 -US20110152240A1,3,O=C1CSC(=O)N1.O=Cc1cnn2c(NC3CC3)cc(Cl)nc12>>O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Cl)nc23)S1 -US20090286768A1,1,OB(O)c1ccccc1.Oc1ccc(Br)cc1F>>Fc1cc(Br)ccc1Oc1ccccc1 -US20050038076A1,1,CI.O=[N+]([O-])c1ccc(O)cc1F>>COc1ccc([N+](=O)[O-])c(F)c1 -US20120040984A1,6,CC(C)(C)OC(=O)C[C@@H]1CC[C@@H](c2ccc(C(=O)Nc3nnc(CS(=O)Cc4ccccc4)s3)cc2)CC1>>O=C(O)C[C@@H]1CC[C@@H](c2ccc(C(=O)Nc3nnc(CS(=O)Cc4ccccc4)s3)cc2)CC1 -US20140128387A1,7,Cc1cc2c(c([N+](=O)[O-])c1)OC(CO)C2>>Cc1cc(N)c2c(c1)CC(CO)O2 -US05011828,7,C=CCn1c(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21>>CCCn1c(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21 -US20130217665A1,2,CC1CCCN(C2(C(=O)O)CC2)C1.N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2)CC1>>CC1CCCN(C2(C(=O)N3C[C@H](S(=O)(=O)c4ccccc4Cl)C[C@H]3C(=O)NC3(C#N)CC3)CC2)C1 -US20040192685A1,1,COc1ccc(C(=O)CNCc2ccccc2)cc1.COc1cccc(C=O)c1>>COc1ccc(C(=O)CN(Cc2ccccc2)Cc2cccc(OC)c2)cc1 -US06335360B1,2,CC[C@H](NC(=O)OCc1ccccc1)C(=O)N1c2ccccc2C[C@H]1C(=O)O.NCC(F)(F)F>>CC[C@H](NC(=O)OCc1ccccc1)C(=O)N1c2ccccc2C[C@H]1C(=O)NCC(F)(F)F -US06933304B2,1,C1=COCCC1.N#Cc1cccc(CO)c1>>N#Cc1cccc(COC2CCCCO2)c1 -US20150175623A1,1,CN1CCN(CCO)CC1.Cc1c(B2OC(C)(C)C(C)(C)O2)ccc(O)c1Cl>>Cc1c(B2OC(C)(C)C(C)(C)O2)ccc(OCCN2CCN(C)CC2)c1Cl -US05674886,1,ClCc1cscn1.c1cc2nonc2cc1Nn1cnnc1>>c1nc(CN(c2ccc3nonc3c2)n2cnnc2)cs1 -US20120121540A1,6,COC(=O)c1cc(C(F)(F)F)c2nc(C(=O)NCc3cccs3)c(Cl)n2c1>>O=C(O)c1cc(C(F)(F)F)c2nc(C(=O)NCc3cccs3)c(Cl)n2c1 -US07101892B2,3,Brc1cccnc1.[Mg+]C1CCCC1>>c1cncc(C2CCCC2)c1 -US07425568B2,9,Oc1ccc2c(c1)C(O)CC(c1cc(F)ccc1F)O2>>Oc1ccc2c(c1)CCC(c1cc(F)ccc1F)O2 -US20090192147A1,7,CCOC(=O)c1cc2cc(OC)ccc2n1CCCl>>COc1ccc2c(c1)cc(CO)n2CCCl -US06204293B1,1,COC(=O)c1ccc(CCl)cc1-c1ccccc1C.OCc1ccc(-c2ccccc2)o1>>COC(=O)c1ccc(COCc2ccc(-c3ccccc3)o2)cc1-c1ccccc1C -US08778939B2,2,Nc1ccnnc1.O=C(O)c1cc(Br)ccc1OCc1ccccc1>>O=C(Nc1ccnnc1)c1cc(Br)ccc1OCc1ccccc1 -US20130338139A1,1,COc1ccc(Cn2c(=O)n3ncnc3c3cc(C(C)=O)cnc32)cc1.C[C@H]1CNC[C@@H](C)O1>>COc1ccc(Cn2c(=O)n3ncnc3c3cc(C(C)N4C[C@H](C)O[C@H](C)C4)cnc32)cc1 -US07176231B2,3,CC(=O)c1ccc2c(c1)CC(=O)N2C(C)=O.O=C(O)c1ccc2c(c1)OCCO2>>CC(=O)c1ccc2c(c1)C(=C(O)c1ccc3c(c1)OCCO3)C(=O)N2C(C)=O -US20060135517A1,1,Cc1cc(Br)c2nc(-c3cccc(C)n3)c(-c3ccnc(N)n3)n2c1.NCCc1ccncc1>>Cc1cc(NCCc2ccncc2)c2nc(-c3cccc(C)n3)c(-c3ccnc(N)n3)n2c1 -US06596719B1,2,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(C2CC2)nc1OCCCN.O=S(=O)(Cl)c1cccs1>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(C2CC2)nc1OCCCNS(=O)(=O)c1cccs1 -US04175203,7,CCOC(=O)C=Cc1ccccc1CC#N>>CCOC(=O)CCc1ccccc1CC#N -US20120208827A1,1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.O=[N+]([O-])c1cccc(Br)c1F>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2c(Br)cccc2[N+](=O)[O-])C1 -US08399436B2,2,Nc1ccn(Cc2ccc(Cl)cc2C(F)(F)F)n1.O=C(O)c1ccncc1F>>O=C(Nc1ccn(Cc2ccc(Cl)cc2C(F)(F)F)n1)c1ccncc1F -US06472403B2,1,Brc1ccc(Br)nc1.CC[O-]>>CCOc1ccc(Br)cn1 -US03953595,1,O=C(CBr)c1ccccc1.O=C(O)c1cc(O)cc(C(F)(F)F)c1>>O=C(O)c1cc(OCC(=O)c2ccccc2)cc(C(F)(F)F)c1 -US05344830,1,CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2cccc(Cl)c2)[C@H](C(=O)NCCNCC(N)=O)C1.COc1ccccc1CCl>>CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2cccc(Cl)c2)[C@H](C(=O)NCCN(CC(N)=O)Cc2ccccc2OC)C1 -US05204477,3,CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](Br)CC2)CC1.CCOc1ccc(Br)cn1>>CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](c3ccc(OCC)nc3)CC2)CC1 -US04719049,9,N#C[Cu].O=Cc1c2ccccc2c(Cl)c2ccccc12>>N#Cc1c2ccccc2c(C=O)c2ccccc12 -US06964983B2,6,COC(=O)COc1ccc(SCc2ccc(OCc3ccc(F)cc3F)cc2)c2c1CCC2>>O=C(O)COc1ccc(SCc2ccc(OCc3ccc(F)cc3F)cc2)c2c1CCC2 -US20140142074A1,7,COC(=O)Cc1ccc(OCC2CC2)c([N+](=O)[O-])c1>>COC(=O)Cc1ccc(OCC2CC2)c(N)c1 -US20030216410A1,3,Cc1[nH]c(C=O)c(C)c1C(=O)NCCCN(C)C.O=C1Cc2cc(-c3ccccc3)ccc2N1>>Cc1[nH]c(C=C2C(=O)Nc3ccc(-c4ccccc4)cc32)c(C)c1C(=O)NCCCN(C)C -US05981559,6,CCOC(=O)COc1ccc(CCCS(=O)(=O)c2ccc(Cl)cc2)cc1NC(=O)c1cccc(C=Cc2nc(-c3ccccc3)cs2)c1>>O=C(O)COc1ccc(CCCS(=O)(=O)c2ccc(Cl)cc2)cc1NC(=O)c1cccc(C=Cc2nc(-c3ccccc3)cs2)c1 -US20120322788A1,1,CCc1cc(C(=O)N2CCOC3(CCNCC3)C2)cs1.OCCc1cc(CBr)ccc1F>>CCc1cc(C(=O)N2CCOC3(CCN(Cc4ccc(F)c(CCO)c4)CC3)C2)cs1 -US04555507,9,CCOCO[C@]1(C(=O)COC(C)=O)[C@@H](C)C[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@@]3(Br)[C@@H](O)C[C@@]21C>>CCOCO[C@]1(C(=O)COC(C)=O)[C@@H](C)C[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C -US07375227B2,1,CC(C)(C)OC(=O)NCCBr.c1ccc(CC2CCNCC2)cc1>>CC(C)(C)OC(=O)NCCN1CCC(Cc2ccccc2)CC1 -US20140194408A1,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)ccnc1N1CCn2c(cc3c2CCCC3)C1=O.Cn1cc(Br)cc(Nc2cc3n(n2)CCN(C2CC2)C3)c1=O>>CC(=O)OCc1c(-c2cc(Nc3cc4n(n3)CCN(C3CC3)C4)c(=O)n(C)c2)ccnc1N1CCn2c(cc3c2CCCC3)C1=O -US04168385,1,COC(=O)C(Br)c1ccc(Oc2ccc(Cl)cc2)cc1.Oc1cccc2c1CCC2>>COC(=O)C(Oc1cccc2c1CCC2)c1ccc(Oc2ccc(Cl)cc2)cc1 -US20130109682A1,7,C[C@]1(O)C(=O)C[C@H](c2ccncc2[N+](=O)[O-])O[C@@H]1C1CC1>>C[C@]1(O)[C@H](O)C[C@H](c2ccncc2[N+](=O)[O-])O[C@@H]1C1CC1 -US20120015991A1,3,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)OC(C)C1CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC(=O)OC(C)C4CC4)cc3)cc2)CC1 -US20100041651A1,1,C1CCNC1.Nc1nc(Cl)ccc1[N+](=O)[O-]>>Nc1nc(N2CCCC2)ccc1[N+](=O)[O-] -US20080167354A1,7,CCC(=CCO[C@@H]1CCC[C@H](OCc2nc(-c3ccc(F)cc3)oc2C)C1)C(=O)O>>CCC(CCO[C@@H]1CCC[C@H](OCc2nc(-c3ccc(F)cc3)oc2C)C1)C(=O)O -US05000775,1,CC(C)N.CCOC(=O)c1sc(Cl)nc1C(F)(F)F>>CCOC(=O)c1sc(NC(C)C)nc1C(F)(F)F -US04218479,6,COc1ccc(CCNCC(O)c2ccccc2OCc2ccccc2)c(OC)c1OC>>COc1ccc(CCNCC(O)c2ccccc2O)c(OC)c1OC -US20150080364A1,2,C1COCCN1.Cc1ccc(C(=O)O)c(CN2CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1ccc(C(=O)N2CCOCC2)c(CN2CCN(C(=O)OC(C)(C)C)CC2)c1 -US04771054,1,CCN1CCC2(CCNC2)C1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21>>CCN1CCC2(CCN(c3c(F)cc4c(=O)c(C(=O)O)cn(CC)c4c3F)C2)C1 -US20040209921A1,2,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N(Cc1ccc(CN)cc1CO)C1CCCc2cccnc21>>CC(=O)NCc1ccc(CN(C(=O)OC(C)(C)C)C2CCCc3cccnc32)c(CO)c1 -US20040132720A1,1,C1CNCCN1.Cc1cc([N+](=O)[O-])ccc1F>>Cc1cc([N+](=O)[O-])ccc1N1CCNCC1 -US06953857B2,6,COC(=O)c1ccc(Cl)c(OCCc2ccc(OC)cc2)c1>>COc1ccc(CCOc2cc(C(=O)O)ccc2Cl)cc1 -US04997847,2,COc1ccc(S(=O)(=O)Cl)cc1.NCCCCCCCC(=O)O>>COc1ccc(S(=O)(=O)NCCCCCCCC(=O)O)cc1 -US08557797B2,2,Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1.O=C(Cl)CCl>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)CCl)cc1 -US08318949B2,1,CC(=O)c1sc(N2CCNC2=O)nc1C.Fc1ccc(CBr)cc1>>CC(=O)c1sc(N2CCN(Cc3ccc(F)cc3)C2=O)nc1C -US20130178457A1,2,C1CCNC1.Cc1cccc2c(Cl)ncc(C(=O)O)c12>>Cc1cccc2c(Cl)ncc(C(=O)N3CCCC3)c12 -US20030092880A1,1,CCCCCCCCBr.COc1ccc2c(c1)[nH]c1cc(OC)ccc12>>CCCCCCCCn1c2cc(OC)ccc2c2ccc(OC)cc21 -US05972976,1,COCCBr.COc1ccc(S(=O)(=O)Nc2ccccc2/C=C/c2ccncc2)cc1>>COCCN(c1ccccc1/C=C/c1ccncc1)S(=O)(=O)c1ccc(OC)cc1 -US20090082365A1,7,CN(C)Cc1cc(Cl)ccc1[N+](=O)[O-]>>CN(C)Cc1cc(Cl)ccc1N -US20090286778A1,6,CC(C)(C)OC(=O)Nc1cccc(CNC(=O)c2cccc([N+](=O)[O-])c2)c1>>Nc1cccc(CNC(=O)c2cccc([N+](=O)[O-])c2)c1 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2cncnc2)c1.CC(C)CNc1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl>>CC(C)CNc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cncnc3)c2)cc1Cl -US06117873,9,COc1nc2cc(Br)cc(CBr)c2nc1OC.[N-]=[N+]=[N-]>>COc1nc2cc(Br)cc(CN=[N+]=[N-])c2nc1OC -US04254116,1,CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)c1ccncc1-2.O=C(O)CCCN1CCSCC1>>CCCCCC(C)C(C)c1cc(OC(=O)CCCN2CCSCC2)c2c(c1)OC(C)(C)c1ccncc1-2 -US20030092694A1,1,Clc1ccccc1OCCOc1nccnc1Cl.NC1CCNC1>>NC1CCN(c2nccnc2OCCOc2ccccc2Cl)C1 -US07091222B2,1,BrCC1CC1.Cc1cc(C#Cc2c[nH]c(C)n2)ccn1>>Cc1cc(C#Cc2cn(CC3CC3)c(C)n2)ccn1 -US07858781B2,3,CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc3c(Br)cccc3[nH]2)CC1.COc1ccc(B(O)O)cn1>>COc1ccc(-c2cccc3[nH]c(C(=O)NC4CCN(C(=O)OC(C)(C)C)CC4)cc23)cn1 -US20120129858A1,2,NS(=O)(=O)c1ccc(F)cc1.O=C(O)c1cccc(-c2ccc(OCCc3ccc(Cl)cc3)nn2)c1>>O=C(NS(=O)(=O)c1ccc(F)cc1)c1cccc(-c2ccc(OCCc3ccc(Cl)cc3)nn2)c1 -US07947676B2,7,Cc1cc([N+](=O)[O-])ccc1OCc1cccc(F)c1>>Cc1cc(N)ccc1OCc1cccc(F)c1 -US09040522B2,2,C1COCCN1.Cc1cc(C#N)c(F)cc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>Cc1cc(C#N)c(F)cc1-c1cnn(-c2ccc(C(=O)N3CCOCC3)cn2)c1O -US06358985B1,1,N#Cc1ccc(Cn2cncc2CCN)cc1F.O=Cc1ccccc1NC(=O)c1cccc(O)c1>>N#Cc1ccc(Cn2cncc2CCNCc2ccccc2NC(=O)c2cccc(O)c2)cc1F -US08163737B2,2,CC(C)(C)CCN1C(=O)C(CC(=O)O)SC1c1cccc(F)c1NCCN1CCOCC1.O=C1Nc2ccccc2CCN1C1CCNCC1>>CC(C)(C)CCN1C(=O)[C@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)SC1c1cccc(F)c1NCCN1CCOCC1 -US20050234096A1,2,CC(C)(CN)c1ccc(OCc2ccccc2)cc1.O=CO>>CC(C)(CNC=O)c1ccc(OCc2ccccc2)cc1 -US20110112100A1,2,CC(C)(N)C(=O)O.COC(=O)Cl>>COC(=O)NC(C)(C)C(=O)O -US06894061B2,1,COc1ccc(S(=O)(=O)NC(C)c2ccccc2-c2ccc(F)cc2F)c(OC)c1>>COc1ccc(S(=O)(=O)N2c3cc(F)ccc3-c3ccccc3C2C)c(OC)c1 -US04764522,6,CC(C)(C)OC(=O)NCCNC(=O)c1ncccc1Oc1ccccc1>>NCCNC(=O)c1ncccc1Oc1ccccc1 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.Cc1cc(C(=O)O)n[nH]1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)c4cc(C)[nH]n4)nc3cc21 -US07176212B2,1,Clc1nccc(Nc2ccccc2)n1.Nc1ccc(O)cc1>>Oc1ccc(Nc2nccc(Nc3ccccc3)n2)cc1 -US20140371199A1,3,CN1CCN(C(=O)c2ccc(-c3cn4c(I)cnc4cn3)cc2)CC1.OB(O)c1ccc(C(F)(F)F)cc1>>CN1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(C(F)(F)F)cc5)cnc4cn3)cc2)CC1 -US05821240,1,CSc1ncc2ncnc(O)c2n1.Nc1ccc(F)c(Cl)c1>>CSc1ncc2ncnc(Nc3ccc(F)c(Cl)c3)c2n1 -US05462941,1,Clc1nnc(-c2ccco2)c2ccccc12.c1c[nH]cn1>>c1coc(-c2nnc(-n3ccnc3)c3ccccc23)c1 -US20130203732A1,6,Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2NC(=O)OC(C)(C)C)c1C1CCC(N)CC1>>Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1CCC(N)CC1 -US20130079323A1,6,CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC(NC(=O)OC(C)(C)C)C3)c2c1Cl>>CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC(N)C3)c2c1Cl -US20140142097A1,3,COC(=O)c1ccc(B(O)O)cc1F.Nc1ncc(Br)cc1C(=O)Nc1ccncc1>>COC(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccncc3)c2)cc1F -US08158625B2,1,COCc1cc2ccccc2[nH]1.Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(Cl)nc21>>COCc1cc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1 -US20130032764A1,3,Brc1c2ccccc2c(-c2cnc(-c3ccccn3)nc2)c2ccccc12.OB(O)c1ccc2ccc3ccccc3c2c1>>c1ccc(-c2ncc(-c3c4ccccc4c(-c4ccc5ccc6ccccc6c5c4)c4ccccc34)cn2)nc1 -US20120029023A1,9,Nc1ncc(Cl)cc1-c1cc(Cc2ccc(OCc3ccccc3)cc2)on1>>Nc1ncccc1-c1cc(Cc2ccc(OCc3ccccc3)cc2)on1 -US20150274695A1,7,O=C(O)c1cc(F)nc(F)c1>>OCc1cc(F)nc(F)c1 -US20140163009A1,1,C1NCC12COC2.COC(=O)[C@H]1[C@H](c2ccc(Br)cc2)[C@H]1c1ccccc1>>COC(=O)[C@H]1[C@H](c2ccc(N3CC4(COC4)C3)cc2)[C@H]1c1ccccc1 -US08598168B2,2,CC(=O)Oc1ccc(C(=O)O)cc1.CC(C)(C)OC(=O)Nc1ccc(C2=CC(=O)CC2)cc1N>>CC(=O)Oc1ccc(C(=O)Nc2cc(C3=CC(=O)CC3)ccc2NC(=O)OC(C)(C)C)cc1 -US20110281884A1,1,CC(=O)c1cc(Cl)c2cncn2c1N1CCN(C(C)=O)CC1.[NH4+]>>CC(=O)N1CCN(c2c(C(C)N)cc(Cl)c3cncn23)CC1 -US20150274704A1,2,Cn1cnc(Nc2ncc(Cl)c(NC3CCC4(CCNCC4)CC3)n2)c1.N#CCC(=O)O>>Cn1cnc(Nc2ncc(Cl)c(NC3CCC4(CC3)CCN(C(=O)CC#N)CC4)n2)c1 -US20080293716A1,2,COc1cccc(CN)c1.O=C(O)c1ccc(Br)s1>>COc1cccc(CNC(=O)c2ccc(Br)s2)c1 -US20110003784A1,2,C1COCCN1.CC1(C)C=C(/C=C/C(=O)O)C(C)(C)CC1>>CC1(C)C=C(/C=C/C(=O)N2CCOCC2)C(C)(C)CC1 -US20100016319A1,1,C1COCCN1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2cc(Cl)ncn2)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2cc(N3CCOCC3)ncn2)cc1 -US20060122234A1,3,Brc1ncccn1.O=C(O)c1ccc(B(O)O)s1>>O=C(O)c1ccc(-c2ncccn2)s1 -US04609650,1,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O.CC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]2(C)[C@H]1OC(=O)CBr>>CC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]2(C)[C@H]1OC(=O)COC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C -US20080171748A1,2,CN.COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)[C@H](CC(=O)O)C[C@@H]3c3ccc(OC)cc3)cc21>>CNC(=O)C[C@@H]1C[C@H](c2ccc(OC)cc2)[C@@H](OCc2ccc3c(c2)N(CCCOC)CCO3)CN1C(=O)OCc1ccccc1 -US20030176454A1,1,Clc1nccc2c(Br)cccc12.Nc1cccc(-n2ccnc2)c1>>Brc1cccc2c(Nc3cccc(-n4ccnc4)c3)nccc12 -US05112922,1,CNC.NC(=O)CCCCBr>>CN(C)CCCCC(N)=O -US20110230470A1,6,COC(=O)C(C)(C)CN1C(=O)c2ccccc2C1=O>>COC(=O)C(C)(C)CN -US20100179197A1,6,COC(=O)c1cnc(Cl)c(OC)c1>>COc1cc(C(=O)O)cnc1Cl -US20100029720A1,3,CC(C)(CCC(C#N)(c1ccccc1)c1ccccc1)N1CC[C@H](OCc2cccc(Br)c2)C1.OB(O)c1ccccc1O>>CC(C)(CCC(C#N)(c1ccccc1)c1ccccc1)N1CC[C@H](OCc2cccc(-c3ccccc3O)c2)C1 -US04916209,2,C[C@H](N)C(=O)O.O=C(Cl)CCl>>C[C@H](NC(=O)CCl)C(=O)O -US20050176701A1,3,CC1(C)OC(=O)C=C(CC(O)(C#C[Si](C)(C)C)C2CCCC2)O1.N#CC1(c2ccc(Br)cc2F)CC1>>CC1(C)OC(=O)C=C(CC(O)(C#Cc2ccc(C3(C#N)CC3)c(F)c2)C2CCCC2)O1 -US04898880,6,CCOC(=O)Cn1ncc(-c2ccccc2)c1-c1ccccc1>>O=C(O)Cn1ncc(-c2ccccc2)c1-c1ccccc1 -US20100292212A1,1,CC(=O)c1ccc(I)cc1.O=C1NCCC12CCN(S(=O)(=O)c1ccccc1Cl)CC2>>CC(=O)c1ccc(N2CCC3(CCN(S(=O)(=O)c4ccccc4Cl)CC3)C2=O)cc1 -US20110294850A1,2,CC1(C)CN(Cc2cccnc2)c2ccc(O)cc21.O=C=NCC1CCCCC1>>CC1(C)CN(Cc2cccnc2)c2ccc(OC(=O)NCC3CCCCC3)cc21 -US20080045534A1,7,Cc1ccc([N+](=O)[O-])c(C)c1NC(=O)CCC1CCCC1>>Cc1ccc(N)c(C)c1NC(=O)CCC1CCCC1 -US07115640B2,9,COC(=O)c1cccc(CBr)c1.[N-]=[N+]=[N-]>>COC(=O)c1cccc(CN=[N+]=[N-])c1 -US20120220592A1,10,Cc1ccc(F)c(OCC(F)(F)F)c1.O=C1CCC(=O)N1Br>>Fc1ccc(CBr)cc1OCC(F)(F)F -US20060116383A1,6,COC(=O)CC(C)n1cnc2cc(N)ccc21>>CC(CC(=O)O)n1cnc2cc(N)ccc21 -US05892055,7,COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C>>CC(C)[C@H]1c2ccc(F)cc2CC[C@]1(O)CCN(C)CCCc1nc2ccccc2[nH]1 -US20100167986A1,1,Cc1cc(N)on1.O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)on1 -US06114390,2,CC(C)(C)OC(=O)N[C@H](CCCNC(N)=N[N+](=O)[O-])C(=O)O.NCc1ccc(CNC(N)=O)cc1>>CC(C)(C)OC(=O)N[C@H](CCCNC(N)=N[N+](=O)[O-])C(=O)NCc1ccc(CNC(N)=O)cc1 -US07087601B2,10,COCOc1cc(-c2nc3ccccc3o2)ccc1C.O=C1CCC(=O)N1Br>>COCOc1cc(-c2nc3ccccc3o2)ccc1CBr -US20040122001A1,6,C=CCN1CCCc2cc(C(=O)OC)ccc21>>C=CCN1CCCc2cc(C(=O)O)ccc21 -US20110065681A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1.CCN(CC)CC(O)c1cc(Br)cc(C(=O)OC)c1>>CCN(CC)CC(O)c1cc(C(=O)OC)cc(-c2ccc(C)cn2)c1 -US20120122846A1,7,Cc1nn(COCC[Si](C)(C)C)c2cc([N+](=O)[O-])ccc12>>Cc1nn(COCC[Si](C)(C)C)c2cc(N)ccc12 -US20110263571A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=C(O)c1ccc(Br)c(F)c1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Br)c(F)c2)CC1 -US20050171350A1,3,CC(C)C[Mg+].Clc1cc(Cl)nc(Cl)n1>>CC(C)Cc1cc(Cl)nc(Cl)n1 -US05098996,6,CC(C)(C)OC(=O)CN(CBr)C(=O)c1ccccc1>>O=C(O)CN(CBr)C(=O)c1ccccc1 -US20150065480A1,2,CCOCCNc1ccccc1C(=O)OCC.N#CCC(=O)O>>CCOCCN(C(=O)CC#N)c1ccccc1C(=O)OCC -US20130237541A1,2,COc1ccc(N)cc1-c1c(Br)cnn1C.COc1ccc(N=C=O)cc1>>COc1ccc(NC(=O)Nc2ccc(OC)c(-c3c(Br)cnn3C)c2)cc1 -US05436257,6,COCOc1c(C)cc(C(O)CN)cc1C>>Cc1cc(C(O)CN)cc(C)c1O -US20100210592A1,3,CC(C)(C)c1ccc(Br)cc1.CON(C)C(=O)C(NC(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)NC(C(=O)c1ccc(C(C)(C)C)cc1)c1ccc(Cl)c(Cl)c1 -US06313310B1,3,C#CC(O)c1ccc(O)cc1.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CC(O)c3ccc(O)cc3)c21 -US06784181B2,1,CCN(CC)C(=O)c1ccc(C(c2cccc3cccnc23)N2CCNCC2)cc1.Cc1ccc(CBr)cc1>>CCN(CC)C(=O)c1ccc(C(c2cccc3cccnc23)N2CCN(Cc3ccc(C)cc3)CC2)cc1 -US20150225400A1,3,CCOc1ccc(F)c(B(O)O)c1.CCc1cnc([C@H]2CC[C@@]3(CCN(C)C3=O)N2)cc1Br>>CCOc1ccc(F)c(-c2cc([C@H]3CC[C@@]4(CCN(C)C4=O)N3)ncc2CC)c1 -US04436726,2,CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)O.C[C@H](N)C(=O)N[C@H](C(=O)O)[C@@H](C)O>>CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)O)[C@@H](C)O -US06300352B1,7,CNC(=O)Cc1cccc(Br)c1>>CNCCc1cccc(Br)c1 -US05192778,1,CCOC(CC)OCN1CCNC1=N[N+](=O)[O-].ClCc1ccc(Cl)nc1>>CCOC(CC)OCN1CCN(Cc2ccc(Cl)nc2)C1=N[N+](=O)[O-] -US08273740B2,6,CC(C)(C)OC(=O)Cn1c(SCCCN(CCc2ccccc2)C(=O)OC(C)(C)C)nc2ccccc21>>CC(C)(C)OC(=O)Cn1c(SCCC[NH2+]CCc2ccccc2)nc2ccccc21 -US07935721B2,8,O=C1N(CCCO)c2ccccc2C12COc1cc3c(cc12)OCO3>>O=CCCN1C(=O)C2(COc3cc4c(cc32)OCO4)c2ccccc21 -US05561147,1,NCc1ccccc1.OCCCSc1ccncc1>>c1ccc(CNCCCSc2ccncc2)cc1 -US08563552B2,1,CC1CNCC(C)C1.Cc1cc(C)nc(Cl)n1>>Cc1cc(C)nc(N2CC(C)CC(C)C2)n1 -US20140235628A1,3,C#CC1(O)CCN(C(=O)OC(C)(C)C)CC1.N#Cc1cc(I)ccc1F>>CC(C)(C)OC(=O)N1CCC(O)(C#Cc2ccc(F)c(C#N)c2)CC1 -US06583154B1,1,CN(C)CC1CCCCN1.Cc1nc(Cl)c2nc(-c3ccccc3)cc-2[nH]1>>Cc1nc(N2CCCCC2CN(C)C)c2nc(-c3ccccc3)cc-2[nH]1 -US09156831B2,2,Cn1nc(C2CCNCC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1.O=C(O)CCOC1CCCCO1>>Cn1nc(C2CCN(C(=O)CCOC3CCCCO3)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 -US20080312281A1,2,O=C(Cl)OCC(Cl)(Cl)Cl.c1cc(CCCCC2CCNCC2)ccn1>>O=C(OCC(Cl)(Cl)Cl)N1CCC(CCCCc2ccncc2)CC1 -US07462641B2,2,CC(C)(C)OC(=O)N[C@H](C(=O)O)C(c1ccc(F)cc1)c1ccc(F)cc1.N#C[C@@H]1C[C@H](F)CN1>>CC(C)(C)OC(=O)N[C@H](C(=O)N1C[C@@H](F)C[C@H]1C#N)C(c1ccc(F)cc1)c1ccc(F)cc1 -US20100048568A1,2,Cc1nc(-c2cccc(F)c2)ncc1C(=O)O.Nn1ccc2cc([N+](=O)[O-])ccc21>>Cc1nc(-c2cccc(F)c2)ncc1C(=O)Nn1ccc2cc([N+](=O)[O-])ccc21 -US08394570B2,2,O=C(O)C1CCCCC1.O=S(=O)([O-])CCO>>O=C(OCCS(=O)(=O)[O-])C1CCCCC1 -US05763450,9,NO.O=C1Nc2ccc(Br)cc2C1=O>>O=C1C(=NO)Nc2ccc(Br)cc21 -US20080306102A1,1,CI.O=C(COc1ccccc1C(F)(F)F)N1CCC2(CC1)C(=O)Nc1ccccc12>>CN1C(=O)C2(CCN(C(=O)COc3ccccc3C(F)(F)F)CC2)c2ccccc21 -US20070225307A1,7,COc1cc2nc(C)nc(Oc3ccc([N+](=O)[O-])cc3)c2cc1OC>>COc1cc2nc(C)nc(Oc3ccc(N)cc3)c2cc1OC -US20110212918A1,9,CC(C)(O)c1cccnc1N>>CC(C)c1cccnc1N -US20030027733A1,6,COC(=O)[C@@H](N)CCCNC(=N)N>>N=C(N)NCCC[C@H](N)C(=O)O -US20140243298A1,6,C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(/C=C/c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(/C=C/c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US07045545B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H](N)CO>>C[C@H](CO)NC(=O)OC(C)(C)C -US20090306139A1,6,COC(=O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CCC(NC(=O)OC(C)(C)C)CC2)C1>>CC(C)(C)OC(=O)NC1CCN(C(=O)N2CC(C(=O)O)CC(c3ccc(OC(F)(F)F)cc3)C2)CC1 -US20150038416A1,1,CCCCCCCOc1ccc(C(=O)CBr)cc1.O=C(O)c1ccc(Br)cc1>>CCCCCCCOc1ccc(C(=O)COC(=O)c2ccc(Br)cc2)cc1 -US05527955,1,N#CCCCBr.c1ccc(CNCc2ccccc2)cc1>>N#CCCCN(Cc1ccccc1)Cc1ccccc1 -US06936602B1,1,CC#CCBr.CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3)cc1>>CC#CCN1CCC(C(=O)OC)=Cc2cc(-c3ccc(OCCOCCCC)cc3)ccc21 -US07687664B2,3,CC1(C)OB(c2ccc(O)cc2)OC1(C)C.COC(=O)Cc1cccc(Br)c1>>COC(=O)Cc1cccc(-c2ccc(O)cc2)c1 -US20150065482A1,1,CC(C)(C)[Si](C)(C)OCCBr.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC1(C)OB(c2cnn(CCO[Si](C)(C)C(C)(C)C)c2)OC1(C)C -US08686048B2,3,CCc1cccc(B(O)O)c1.Nc1ccc(Br)cc1>>CCc1cccc(-c2ccc(N)cc2)c1 -US20090137804A1,1,CNc1cc(Cl)ncn1.N#Cc1cccc(N)c1>>CNc1cc(Nc2cccc(C#N)c2)ncn1 -US20120232028A1,3,COC(=O)CCCCN(Cc1ccc(OC)cc1)c1cc(C)c(Br)cc1C=O>>COC(=O)C1=Cc2cc(Br)c(C)cc2N(Cc2ccc(OC)cc2)CCC1 -US05688809,1,Nc1ccc2[nH]ccc2c1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1Nc1ccc2[nH]ccc2c1 -US20070161631A1,6,CCOC(=O)COc1cc(F)ccc1C(=S)NCc1nc2c(F)c(F)cc(F)c2s1>>O=C(O)COc1cc(F)ccc1C(=S)NCc1nc2c(F)c(F)cc(F)c2s1 -US20090004185A1,2,CCOC(=O)N=C=S.Nc1cccc(I)c1>>CCOC(=O)NC(=S)Nc1cccc(I)c1 -US20070293521A1,1,Fc1cnc(Cl)nc1Nc1ccc2c(c1)OCCO2.Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1>>Fc1cnc(Nc2ccc(N3CCN(Cc4ccccc4)CC3)cc2)nc1Nc1ccc2c(c1)OCCO2 -US06593326B1,1,O=[N+]([O-])c1ccc(OCCCBr)cc1.c1c[nH]cn1>>O=[N+]([O-])c1ccc(OCCCn2ccnc2)cc1 -US04742084,1,C=O.COc1ccc(C#Cc2ccccc2)c(CCNCCc2ccc(OC)c(OC)c2)c1>>COc1ccc(C#Cc2ccccc2)c(CCN(C)CCc2ccc(OC)c(OC)c2)c1 -US07109200B2,2,CCOC(CN)OCC.O=C(Cl)OCc1ccccc1>>CCOC(CNC(=O)OCc1ccccc1)OCC -US20090318412A1,7,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(C(=O)O)C1>>CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(CO)C1 -US07884210B2,6,COC(=O)[C@@H]1CCCN1S(=O)(=O)c1cnc(NC(=O)N(CC2CCCC2)c2ccc(F)c(F)c2)s1>>O=C(O)[C@@H]1CCCN1S(=O)(=O)c1cnc(NC(=O)N(CC2CCCC2)c2ccc(F)c(F)c2)s1 -US05196434,1,CN1CS(=O)c2cc(CCBr)ccc21.CNCc1ccccc1>>CN(CCc1ccc2c(c1)S(=O)CN2C)Cc1ccccc1 -US04806549,1,COc1cccc2c(Cl)c(C(=O)C(C)C)cnc12.Cc1ccccc1N>>COc1cccc2c(Nc3ccccc3C)c(C(=O)C(C)C)cnc12 -US20100216758A1,9,Fc1cc(Br)ccc1CBr.[C-]#N>>N#CCc1ccc(Br)cc1F -US06759410B1,1,N#Cc1c(F)cccc1-c1ccccc1.NC1CCCCC1>>N#Cc1c(NC2CCCCC2)cccc1-c1ccccc1 -US05089654,3,C=CCCCc1ccc(Br)cc1.CN(C)C=O>>C=CCCCc1ccc(C=O)cc1 -US04087432,5,Nc1ncc(Cl)cc1[N+](=O)[O-].O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ncc(Cl)cc1[N+](=O)[O-])C(F)(F)F -US20130143925A1,2,CC(C)(C)OC(=O)N1CCC(N)CC1.O=C=Nc1ccc(OC(F)(F)F)cc1>>CC(C)(C)OC(=O)N1CCC(NC(=O)Nc2ccc(OC(F)(F)F)cc2)CC1 -US20100093742A1,2,CC(O)C(O)C1CNc2[nH]c(N)nc(=O)c2N1.O=C(Cl)OCc1ccccc1>>CC(O)C(O)C1CNc2[nH]c(N)nc(=O)c2N1C(=O)OCc1ccccc1 -US06211215B1,3,Brc1ccc(-c2nc(COc3ccc(CCCn4ccnc4)cc3)co2)o1.OB(O)c1ccccc1>>c1ccc(-c2ccc(-c3nc(COc4ccc(CCCn5ccnc5)cc4)co3)o2)cc1 -US05994378,4,CCCC(C#N)Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1.[N-]=[N+]=[N-]>>CCCC(Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1)c1nnn[nH]1 -US20070129416A1,2,CC(=O)N1CCNCC1.CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)Cl>>CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(C(C)=O)CC1 -US05866565,2,CN(C)C=Nc1ccncc1O.O=C=Nc1ccccc1>>CN(C)C=Nc1ccncc1OC(=O)Nc1ccccc1 -US06703392B2,1,BrCC1CC1.COc1cc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccc2)ccc1O>>COc1cc2c(cc1OC)C(Cc1ccc(OCC3CC3)c(OC)c1)N(CC(=O)NCc1ccccc1)CC2 -US20070117836A1,2,CN(C)CCN1C(=O)c2cccc3cc(N)cc(c23)C1=O.COc1ccc(N=C=O)cc1>>COc1ccc(NC(=O)Nc2cc3c4c(cccc4c2)C(=O)N(CCN(C)C)C3=O)cc1 -US20150011528A1,2,Cc1ccc2nc(N)sc2c1.O=C(Cl)c1cccc(Cl)c1>>Cc1ccc2nc(NC(=O)c3cccc(Cl)c3)sc2c1 -US06777431B2,1,CCOC(=O)CCn1c(C)cnc(O)c1=O.NCC(F)(F)c1ccccc1>>CCOC(=O)CCn1c(C)cnc(NCC(F)(F)c2ccccc2)c1=O -US20070191421A1,2,Cc1onc(-c2ccccc2)c1C(=O)O.N#Cc1ccc(CN)nc1>>Cc1onc(-c2ccccc2)c1C(=O)NCc1ccc(C#N)cn1 -US09045447B2,6,C=CCCCCCCCC(=O)OC>>C=CCCCCCCCC(=O)O -US03961055,1,CC(C)Oc1ccc2c(c1)Nc1cccc(S(C)(=O)=O)c1S2.ClCCCBr>>CC(C)Oc1ccc2c(c1)N(CCCCl)c1cccc(S(C)(=O)=O)c1S2 -US20100137381A1,2,Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1-c1noc(=O)[nH]1.O=C(Cl)Cc1cc(F)cc(F)c1>>O=C(Cc1cc(F)cc(F)c1)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1-c1noc(=O)[nH]1 -US06664393B2,1,CCOC(=O)c1ccc(OC)c(O)c1.OCCc1ccc(Cl)cc1Cl>>CCOC(=O)c1ccc(OC)c(OCCc2ccc(Cl)cc2Cl)c1 -US20090143385A1,1,Cc1onc(-c2ccc(F)cc2)c1CN.Clc1ccc(Cl)nn1>>Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(Cl)nn1 -US20110230500A1,6,COC(=O)c1nccn(Cc2ccc(F)c(F)c2)c1=O>>O=C(O)c1nccn(Cc2ccc(F)c(F)c2)c1=O -US20140039183A1,3,CCCC[Sn](CCCC)(CCCC)c1cncs1.N#Cc1cc(I)ccc1F>>N#Cc1cc(-c2cncs2)ccc1F -US20020037912A1,4,CC(=O)C1([N+](=O)[O-])C=C(c2nnn[nH]2)C=C(c2ccccc2)C1O.N=C(N)c1ccc(NN)cc1>>N=C(N)c1ccc2[nH]c(C3([N+](=O)[O-])C=C(c4nnn[nH]4)C=C(c4ccccc4)C3O)cc2c1 -US08084620B2,6,CN1CCN(C(=O)c2ccc3c(c2)[nH]c2c(C(N)=O)ccc(N4CCC[C@@H](NC(=O)OCc5ccccc5)C4)c23)CC1>>CN1CCN(C(=O)c2ccc3c(c2)[nH]c2c(C(N)=O)ccc(N4CCC[C@@H](N)C4)c23)CC1 -US20100280268A1,6,COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc(Oc3ccc(NS(=O)(=O)c4ccc(C)cc4)c(C(=O)O)c3)cc2C)cc1 -US07851473B2,2,O=C(Nc1cccnc1)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)nc1>>O=C(Nc1cccnc1)N1CCN(c2nc(-c3ccccn3)ns2)CC1 -USRE043006E1,6,CCOC(=O)C=Cc1cc(C)ccc1OC1CCCCO1>>CCOC(=O)/C=C/c1cc(C)ccc1O -US20060004078A1,7,CCN(CC)CCCCc1ccc([N+](=O)[O-])cc1>>CCN(CC)CCCCc1ccc(N)cc1 -US20140192305A1,1,CCOc1cc(C=O)ccc1O.OCCCCCCCCCCCBr>>CCOc1cc(C=O)ccc1OCCCCCCCCCCCO -US05958954,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(CC)cc2)=CC(C)(C)O3)cc1F>>CCc1ccc(C2=CC(C)(C)Oc3ccc(C#Cc4ccc(C(=O)O)c(F)c4)cc32)cc1 -US20100029736A1,2,CC(C)(C)OC(=O)N1CCC[C@@]1(C)C(=O)O.Nc1ccccc1-c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@@]1(C)C(=O)Nc1ccccc1-c1ccccc1 -US05747537,3,O=C(O)CCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccco1>>O=C(O)CCCCCCCCCC=Cc1ccco1 -US08476265B2,6,CCOC(COc1ccc(CCO)cc1)OCC>>O=CCOc1ccc(CCO)cc1 -US20090325952A1,1,C1COCCN1.CCc1nc2c(cnn2CC)c(NC2CCN(C(N)=O)CC2)c1CNC(=O)c1ccc(CCCCOCCCCBr)cc1>>CCc1nc2c(cnn2CC)c(NC2CCN(C(N)=O)CC2)c1CNC(=O)c1ccc(CCCCOCCCCN2CCOCC2)cc1 -US20090156574A1,1,NC1CCN(Cc2ccccc2)CC1.O=C1CCOCC1>>c1ccc(CN2CCC(NC3CCOCC3)CC2)cc1 -USRE030241,1,CC(C)(C)NCC(=O)c1ccc(O)c(O)c1.Cc1cccc(Cl)c1>>Cc1cccc(Oc2ccc(C(=O)CNC(C)(C)C)cc2O)c1 -US06403586B1,2,CCOC(=O)c1cc(-c2ccc(OC)cc2)nn(CC2CCCC2)c1=O.NCc1ccccc1>>COc1ccc(-c2cc(C(=O)NCc3ccccc3)c(=O)n(CC3CCCC3)n2)cc1 -US05902803,9,CCOC(=O)c1nccn1C1Cc2c(C#N)cccc2C1=O.N>>N#Cc1cccc2c1CC(n1ccnc1C(N)=O)C2=O -US20130244993A1,3,Brc1ccnc(N2CCOCC2)n1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2ccnc(N3CCOCC3)n2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O -US05620996,2,CCCCCCCCCCS(=O)(=O)NC(=O)c1cnc(C(=O)O)c(OC)c1.CCCCOC(=O)CN>>CCCCCCCCCCS(=O)(=O)NC(=O)c1cnc(C(=O)NCC(=O)OCCCC)c(OC)c1 -US07659271B2,3,CON(C)C(=O)c1cc(C#N)cc(C(F)(F)F)c1.C[Mg+]>>CC(=O)c1cc(C#N)cc(C(F)(F)F)c1 -US20140073650A1,2,Cc1ccc(-c2noc(CNC(C)C)n2)cc1.O=C(Cl)COc1ccc(Cl)cc1>>Cc1ccc(-c2noc(CN(C(=O)COc3ccc(Cl)cc3)C(C)C)n2)cc1 -US20130345181A1,1,CC(=O)N1CCN(c2ccc(N)cc2)CC1.CC(C)(C)OC(=O)n1cc(-c2cc3cnc(Cl)cc3n2C(=O)OC(C)(C)C)cn1>>CC(=O)N1CCN(c2ccc(Nc3cc4c(cn3)cc(-c3cnn(C(=O)OC(C)(C)C)c3)n4C(=O)OC(C)(C)C)cc2)CC1 -US05340931,1,C#CCBr.O=C(O)c1ccc(O)cc1>>C#CCOc1ccc(C(=O)O)cc1 -US20070207175A1,3,CCCCOc1cc(C=O)ccc1I.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCOc1cc(/C=C/C(=O)OC)ccc1I -US20120208996A1,1,COC(C=O)OC.COc1cc2c(cc1OC)[C@@H](CN(C)CCCN)C2>>COc1cc2c(cc1OC)[C@@H](CN(C)CCCNCC(OC)OC)C2 -US20040097733A1,1,CCNc1ccc2c(c1)C(CC)=CCC2(C)C.O=C(O)c1ccc(F)nc1>>CCC1=CCC(C)(C)c2ccc(N(CC)c3ccc(C(=O)O)cn3)cc21 -US20150203487A1,9,N.O=C(O)[C@H]1OC[C@@H](Oc2nc3nc(-c4ccc(-c5ccccc5)cc4)c(Cl)cc3[nH]2)[C@@H]1O>>NC(=O)[C@H]1OC[C@@H](Oc2nc3nc(-c4ccc(-c5ccccc5)cc4)c(Cl)cc3[nH]2)[C@@H]1O -US06432950B1,1,Cc1cc2c(Cl)nc(-c3ccncc3)nc2s1.NCCc1ccccc1>>Cc1cc2c(NCCc3ccccc3)nc(-c3ccncc3)nc2s1 -US20110230495A1,7,COC(=O)c1occc1C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccoc2CO)CC1 -US05990151,7,COC(=O)C(=Cc1ccc(OC)c(OCCc2ccccc2)c1)C(=O)OC>>COC(=O)C(Cc1ccc(OC)c(OCCc2ccccc2)c1)C(=O)OC -US06410556B1,6,O=C1c2ccccc2C(=O)N1CC1CC2(CCN1)OCCO2>>NCC1CC2(CCN1)OCCO2 -US06376503B1,1,CC1COC2(CCNCC2)O1.N#Cc1cc(F)ccc1F>>CC1COC2(CCN(c3ccc(F)cc3C#N)CC2)O1 -US20090030196A1,7,C=Cc1ccc2sc3c(=O)[nH]c(CN(C)C)nc3c2c1>>CCc1ccc2sc3c(=O)[nH]c(CN(C)C)nc3c2c1 -US20120289505A1,6,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4ccc(OC)c(OC)c4)cc3)cc2C1=O>>COc1ccc(C(=O)Nc2ccc(-c3ccc4c(c3)C(=O)N([C@H](C(=O)O)C(C)C)C4)cc2)cc1OC -US20150175623A1,3,COc1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1Cl.Clc1ncnc2scc(I)c12>>COc1ccc(-c2csc3ncnc(Cl)c23)c(C)c1Cl -US20090233930A9,3,CN1C(=O)C(c2ccccc2)(c2cccc(Br)c2)N=C1N.COc1cc(O)cc(B2OC(C)(C)C(C)(C)O2)c1>>COc1cc(O)cc(-c2cccc(C3(c4ccccc4)N=C(N)N(C)C3=O)c2)c1 -US06156903,1,CN(C)C1CNC1.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(F)cc1F>>CN(C)C1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4nc(N)c(F)cc4F)c3c2Cl)C1 -US20120088783A1,8,Cc1c(OC2CCCCO2)cc2c(c1C)OC(C)(CCCO)CC2>>Cc1c(OC2CCCCO2)cc2c(c1C)OC(C)(CCC=O)CC2 -US07560463B2,6,CC(C)(C)OC(=O)N1CCc2ccc(Oc3ccc(C(N)=O)cn3)cc2C1>>NC(=O)c1ccc(Oc2ccc3c(c2)CNCC3)nc1 -US07531576B2,1,CCCCCNCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.Cc1cc(C)c(NC(=O)CCl)c(C)c1>>CCCCCN(CC(=O)Nc1c(C)cc(C)cc1C)Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20140349994A1,6,COc1ccc(Cn2ncc3c2N(CCCN2C(=O)c4ccccc4C2=O)CCCC3=O)cc1>>COc1ccc(Cn2ncc3c2N(CCCN)CCCC3=O)cc1 -US20110077248A1,6,CCOC(=O)c1cccn2cc(-c3ccc(CN4CCOCC4)cc3)nc12>>O=C(O)c1cccn2cc(-c3ccc(CN4CCOCC4)cc3)nc12 -US20090233937A1,1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2cccc3sncc23)c(Cl)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21 -US20140309225A1,1,C1COCCN1.Nc1cc(Cl)ncc1F>>Nc1cc(N2CCOCC2)ncc1F -US08445480B2,6,CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)N4CCC5(CCN(C(=O)OC(C)(C)C)CC5)C4)cc3)oc12>>CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)N4CCC5(CCNCC5)C4)cc3)oc12 -US07026312B2,6,CCOC(=O)C(CC(=O)OC(C)(C)C)(Cc1ccc(CC)c(CC)c1)C(=O)OCC>>CCOC(=O)C(CC(=O)O)(Cc1ccc(CC)c(CC)c1)C(=O)OCC -US06218431B1,8,CCOC(=O)c1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1>>CCOC(=O)c1c(C(C)C)nc(C(C)C)c(C=O)c1-c1ccc(F)cc1 -US07361659B2,2,Cc1nc(N)sc1S(=O)(=O)NCCO.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>Cc1nc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)sc1S(=O)(=O)NCCO -US05438058,1,C1CCNCC1.Cc1cc(Cl)nc(C)[n+]1[O-]>>Cc1cc(N2CCCCC2)nc(C)[n+]1[O-] -US20010056211A1,1,BrCCBr.COc1ccccc1O>>COc1ccccc1OCCBr -US20130030012A1,1,N#Cc1cc(C=O)ccc1F.Oc1ccc(Cl)c(F)c1>>N#Cc1cc(C=O)ccc1Oc1ccc(Cl)c(F)c1 -US07371748B2,6,COc1ccc(C2CCOCC2)cc1NC(=S)NC(=O)c1ccccc1>>COc1ccc(C2CCOCC2)cc1NC(N)=S -US05958970,10,CC1CCCCC1=O.O=C1CCC(=O)N1Br>>CC1(Br)CCCCC1=O -US03963725,6,COc1cc2c(cc1O)CCNC2COc1ccc(Cl)cc1>>Oc1cc2c(cc1O)C(COc1ccc(Cl)cc1)NCC2 -US07192948B2,2,CCOC(=O)c1nc2n(c(=O)c1O)CC(=O)N2C.NCc1ccc(F)c(Cl)c1>>CN1C(=O)Cn2c1nc(C(=O)NCc1ccc(F)c(Cl)c1)c(O)c2=O -US20050159444A1,7,O=C(O)[C@@H]1C=C(c2ccccc2)CN1C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CC(c2ccccc2)=C[C@H]1CO -US05457106,1,OCCCBr.Sc1ccncc1>>OCCCSc1ccncc1 -US08372874B2,2,CC(C)(C(=O)O)S(=O)(=O)CC1CC1.CCn1nc(N)nc1-c1ccc(OC)cc1>>CCn1nc(NC(=O)C(C)(C)S(=O)(=O)CC2CC2)nc1-c1ccc(OC)cc1 -US20130030031A1,2,CN1CCOCC1C(=O)O.COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1cccc(CN)c1>>COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1cccc(CNC(=O)C2COCCN2C)c1 -US20110118230A1,3,Brc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCCCC4)cc3)cc12.CCCC[Sn](CCCC)(CCCC)c1cncn1C>>Cn1cncc1-c1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCCCC4)cc3)cc12 -US08609848B2,2,COc1ccc(C2=NN(C3CCNCC3)C(=O)C2(C)C)cc1OC.COc1ncccc1C(=O)O>>COc1ccc(C2=NN(C3CCN(C(=O)c4cccnc4OC)CC3)C(=O)C2(C)C)cc1OC -US08524707B2,9,CCOC(=O)c1csc2c(-c3ccncc3)c(-c3cccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c3)nn12.N>>NC(=O)c1csc2c(-c3ccncc3)c(-c3cccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c3)nn12 -US20050277670A1,2,CC(CCN)N1CCC(C2(c3ccc(C(F)(F)F)cc3)Cc3c(F)cccc3O2)CC1.Cc1ncnc(C)c1C(=O)O>>Cc1ncnc(C)c1C(=O)NCCC(C)N1CCC(C2(c3ccc(C(F)(F)F)cc3)Cc3c(F)cccc3O2)CC1 -US05608062,8,OC(c1ccc(Cl)nc1)C(F)(F)F>>O=C(c1ccc(Cl)nc1)C(F)(F)F -US20100137313A1,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cnc1OC.Cc1cc(C(F)(F)F)nn1-c1nc(Cl)ncc1Br>>COC(=O)c1cc(-c2cnc(Cl)nc2-n2nc(C(F)(F)F)cc2C)cnc1OC -US20100210647A1,1,CC(C)(C)OC(=O)N1CCNCC1.OCC[C@@H]1CSC(c2cc3cc(Cl)cc(NC4CCCC4)c3[nH]2)=N1>>CC(C)(C)OC(=O)N1CCN(CC[C@@H]2CSC(c3cc4cc(Cl)cc(NC5CCCC5)c4[nH]3)=N2)CC1 -US04070539,6,C=C(CC)C(=O)c1ccc(OC(C)C(=O)OCC)c(Cl)c1Cl>>C=C(CC)C(=O)c1ccc(OC(C)C(=O)O)c(Cl)c1Cl -US20090163489A1,2,Nc1cc(Br)cnc1Cl.O=S(=O)(Cl)c1ccc(F)cc1>>O=S(=O)(Nc1cc(Br)cnc1Cl)c1ccc(F)cc1 -US07329658B2,1,CCNC1(C(N)=O)CNC1.Cc1nc(Cl)n2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2n1>>CCNC1(C(N)=O)CN(c2nc(C)nc3c(-c4ccc(Cl)cc4)c(-c4ccccc4Cl)nn23)C1 -US05554594,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCC[C@@H]1NC(=O)N(c2cccc(C(=O)O)c2)C1=O>>CC(C)(C)OC(=O)NCCC[C@@H]1NC(=O)N(c2cccc(C(=O)O)c2)C1=O -US08946697B1,3,Cc1ccc2c(n1)oc1c(B3OC(C)(C)C(C)(C)O3)cccc12.Fc1ccccc1-c1ccnc(Cl)c1>>Cc1ccc2c(n1)oc1c(-c3cc(-c4ccccc4F)ccn3)cccc12 -US07572809B2,6,COC(=O)c1cc2c(cc1OC)CCC2=O>>COc1cc2c(cc1C(=O)O)C(=O)CC2 -US20100016337A1,1,CC(C)(C)OC(=O)CBr.Sc1nc(-c2ccc(Cl)cc2)cs1>>CC(C)(C)OC(=O)CSc1nc(-c2ccc(Cl)cc2)cs1 -US20140114068A1,7,CC(C)c1ccc2c(c1)OC1(O)c3ccc([N+](=O)[O-])c(N)c3C(=O)C21O>>CC(C)c1ccc2c(c1)OC1(O)c3ccc(N)c(N)c3C(=O)C21O -US07374926B2,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1NCC(CO)O1>>Cc1ccc(S(=O)(=O)OCC2CNC(=O)O2)cc1 -US06399619B1,8,CC[C@H](C)[C@H](C(=O)OCc1ccccc1)N1C[C@H](CO)[C@@H](c2cccc(F)c2)C1>>CC[C@H](C)[C@H](C(=O)OCc1ccccc1)N1C[C@H](C=O)[C@@H](c2cccc(F)c2)C1 -US04328202,2,CNCC(O)CO.N#Cc1c(I)c(C(=O)O)c(I)c(C(=O)NCC(O)CO)c1I>>CN(CC(O)CO)C(=O)c1c(I)c(C#N)c(I)c(C(=O)NCC(O)CO)c1I -US07919502B2,2,NCc1ccc(Cl)cc1.O=C(O)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1>>O=C(NCc1ccc(Cl)cc1)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1 -US20100197681A1,3,Nc1cccc(Cl)n1.OB(O)c1ccoc1>>Nc1cccc(-c2ccoc2)n1 -US07935815B2,4,COc1cc(/C=C/C(=O)NNC(=O)C(CCCCl)c2cc(F)c(F)c(F)c2)cnc1-n1cnc(C)c1>>COc1cc(/C=C/c2nnc(C(CCCCl)c3cc(F)c(F)c(F)c3)o2)cnc1-n1cnc(C)c1 -US20130178459A1,6,COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)CNC(=O)OC(C)(C)C)c(F)c1>>COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)CN)c(F)c1 -US20080255083A1,1,O=C(CCl)c1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2.O=c1cc(OCc2ccccc2)cc[nH]1>>O=C(Cn1ccc(OCc2ccccc2)cc1=O)c1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2 -US20050014753A1,6,CCOC(=O)c1ccc(-c2ncnc(Nc3ccc(OC(F)(F)F)cc3)n2)cc1>>O=C(O)c1ccc(-c2ncnc(Nc3ccc(OC(F)(F)F)cc3)n2)cc1 -US05656643,3,C#CC1CCCCC1.COc1cc2cc(OS(=O)(=O)C(F)(F)F)cnc2cc1OC>>COc1cc2cc(C#CC3CCCCC3)cnc2cc1OC -US07276607B2,2,CN[C@H]1CC[C@@H](N2CCC(C)CC2)C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)N(C)[C@H]2CC[C@@H](N3CCC(C)CC3)C2)cc1 -US20130116243A1,1,N#CCBr.O=C1COc2nc(Br)c(-c3ccccc3)cc2N1>>N#CCN1C(=O)COc2nc(Br)c(-c3ccccc3)cc21 -US20090030023A1,1,CCCN.Nc1nc(-c2ccco2)c(-c2ccnc(F)c2)c(-c2ccco2)n1>>CCCNc1cc(-c2c(-c3ccco3)nc(N)nc2-c2ccco2)ccn1 -US20040138449A1,1,CNCC(O)c1c[nH]c2ccccc12.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(CCl)cc21>>CN(Cc1cc2c(s1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C)CC(O)c1c[nH]c2ccccc12 -US04260803,2,Cc1cc(Cl)cc(Cl)c1O.O=C(Cl)c1ccc(CCl)cc1>>Cc1cc(Cl)cc(Cl)c1OC(=O)c1ccc(CCl)cc1 -US20100080770A1,1,C=Cc1cc([C@]2(O)C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C2)cc2ccccc12.CI>>C=Cc1cc([C@]2(OC)C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C2)cc2ccccc12 -US03961055,1,CC(C)Oc1ccc2c(c1)Nc1cccc(S(=O)(=O)N(C)C)c1S2.ClCCCBr>>CC(C)Oc1ccc2c(c1)N(CCCCl)c1cccc(S(=O)(=O)N(C)C)c1S2 -US20130225552A1,7,O=C(O)c1cc(F)cnc1Cl>>OCc1cc(F)cnc1Cl -US08450310B2,3,CCNC(=O)c1noc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)c1Br.CN1CCN(c2cccc(B3OC(C)(C)C(C)(C)O3)c2)CC1>>CCNC(=O)c1noc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1cccc(N2CCN(C)CC2)c1 -US08895050B2,2,CCCC(N)CCC.O=C(O)c1ccc(O)c(O)c1>>CCCC(CCC)NC(=O)c1ccc(O)c(O)c1 -US20140162971A1,7,Cn1cc(-c2cc([N+](=O)[O-])ccc2Oc2ccc(F)cc2)c2cc[nH]c2c1=O>>Cn1cc(-c2cc(N)ccc2Oc2ccc(F)cc2)c2cc[nH]c2c1=O -US06967198B2,1,C1COCCN1.CC(C)(C)OC(=O)Nc1cc2c3c(c(Cl)[nH]c3c1)C=NNC2=O>>CC(C)(C)OC(=O)Nc1cc2c3c(c(N4CCOCC4)[nH]c3c1)C=NNC2=O -US06762180B1,9,N.O=C1Nc2cc(C(=O)O)ccc2/C1=C(/Nc1ccc(Br)cc1)c1ccccc1>>NC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(Br)cc1)c1ccccc1 -US04812164,1,CC(C)OC(=O)c1cc(-n2c(Cl)nc(C(F)(F)C(F)(F)F)cc2=O)c(F)cc1Cl.C[O-]>>COc1nc(C(F)(F)C(F)(F)F)cc(=O)n1-c1cc(C(=O)OC(C)C)c(Cl)cc1F -US20040023989A1,7,CC(C)c1[nH]nc(C(N)=O)c1[N+](=O)[O-]>>CC(C)c1[nH]nc(C(N)=O)c1N -US06258827B1,7,Cc1cc(C(=O)C(C)N2CCC(O)(c3ccc(Cl)cc3)CC2)cc(C)c1O[Si](C(C)C)(C(C)C)C(C)C>>Cc1cc([C@@H](O)[C@@H](C)N2CCC(O)(c3ccc(Cl)cc3)CC2)cc(C)c1O[Si](C(C)C)(C(C)C)C(C)C -US07074387B2,2,CCOC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O>>CCOC(=O)CN(CCN(CCN1CC(=O)OC(=O)C1)CC(=O)O)CC(=O)O -US20100272680A1,6,CC1CC(N2CCOC2=O)CCN1C(=O)OC(C)(C)C>>CC1CC(N2CCOC2=O)CCN1 -US07179812B2,1,Clc1ncc(CCCCn2ccnn2)cn1.OCc1coc(C=Cc2ccc(Cl)cc2F)n1>>Fc1cc(Cl)ccc1C=Cc1nc(COc2ncc(CCCCn3ccnn3)cn2)co1 -US07368578B2,6,CCOC(=O)Cc1ccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4/C=C\c4csc(C(C)C)n4)cc3OC)c(C)o2)cc1>>COc1cc(COc2nn(-c3ccccc3)cc2/C=C\c2csc(C(C)C)n2)ccc1OCc1nc(-c2ccc(CC(=O)O)cc2)oc1C -US20070249620A1,6,COC(=O)c1cccc(C)c1NC(=O)N1CCN(c2ccc(NC(=O)Nc3cc(C)ccc3OC)cc2)CC1>>COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCN(C(=O)Nc3c(C)cccc3C(=O)O)CC2)cc1 -US06638321B1,1,Cc1cc(F)ccc1[N+](=O)[O-].NCCCn1ccnc1>>Cc1cc(NCCCn2ccnc2)ccc1[N+](=O)[O-] -US20090156572A1,2,CN[C@@H]1CCN(C(=O)C2CCN(C(C)=O)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1.Cc1cc(C(=O)O)cc(C(F)(F)F)c1>>CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3cc(C)cc(C(F)(F)F)c3)[C@H](c3ccc(Cl)c(Cl)c3)C2)CC1 -US08338598B2,2,CC(C)C(=O)Cl.Cc1nc(Cl)sc1-c1c(O)c2nccnc2[nH]c1=O>>Cc1nc(Cl)sc1-c1c(OC(=O)C(C)C)c2nccnc2[nH]c1=O -US20090264416A1,2,CCOC(=O)c1ccc(NC(=O)Nc2ccccc2)cc1.COC(=O)c1cccc(CN2CCNCC2)c1>>COC(=O)c1cccc(CN2CCN(C(=O)c3ccc(NC(=O)Nc4ccccc4)cc3)CC2)c1 -US20140179668A1,1,CC(C)c1cc(Nc2nc(N3CCC[C@@H]3C(=O)Nc3ccc(F)nc3)nc3c2CCC3)n[nH]1.C[S-]>>CSc1ccc(NC(=O)[C@H]2CCCN2c2nc3c(c(Nc4cc(C(C)C)[nH]n4)n2)CCC3)cn1 -US20150133457A1,1,COCCBr.COc1cc(N[C@H]2CCNC2)ccc1[N+](=O)[O-]>>COCCN1CC[C@H](Nc2ccc([N+](=O)[O-])c(OC)c2)C1 -US20120252691A1,3,C#CCNC(=O)C(F)(F)F.Nc1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1I>>Nc1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1C#CCNC(=O)C(F)(F)F -US07345050B2,1,Nc1nccc(-c2cnc3ccccn23)n1.O=C(c1ccc(Br)cc1)c1cccc(Cl)c1>>O=C(c1ccc(Nc2nccc(-c3cnc4ccccn34)n2)cc1)c1cccc(Cl)c1 -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)c(Br)c1)Oc1ccccc1>>O=C(NCCOc1ccc(CC(Oc2ccccc2)C(=O)O)cc1Br)c1ccc(-c2ccccn2)cc1 -US04652584,1,COc1ccc(I)c(O)c1.ClCC1CO1>>COc1ccc(I)c(OCC2CO2)c1 -US20090215759A1,1,CC(C)(O)c1cc(-c2ccc(C(F)(F)F)cc2)nc(Cl)n1.COc1cc(N)ccc1-c1cnc(C)s1>>COc1cc(Nc2nc(-c3ccc(C(F)(F)F)cc3)cc(C(C)(C)O)n2)ccc1-c1cnc(C)s1 -US05037834,3,C=O.NCCc1csc(Nc2ccccc2)n1>>c1ccc(Nc2nc3c(s2)CNCC3)cc1 -US20100075976A1,2,CNCCN1CCN(c2nccnc2Cl)CC1.Cc1nn(C)cc1S(=O)(=O)Cl>>Cc1nn(C)cc1S(=O)(=O)N(C)CCN1CCN(c2nccnc2Cl)CC1 -US06821980B1,1,CCCBr.CCOc1cc(Cc2cnc(N)nc2N)cc(O)c1-c1ccc(OC)cc1>>CCCOc1cc(Cc2cnc(N)nc2N)cc(OCC)c1-c1ccc(OC)cc1 -US08273769B2,3,C#Cc1cc(S(=O)(=O)CCC)ccc1C.COCOc1ccc(Cl)cc1Br>>CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCOC)c1 -US20120065196A1,2,Cc1nc(-c2nc3c(s2)CC(C(=O)NCCN)CC3)c[nH]1.O=C(O)c1cn(-c2ccccc2)nc1C(F)(F)F>>Cc1nc(-c2nc3c(s2)CC(C(=O)NCCNC(=O)c2cn(-c4ccccc4)nc2C(F)(F)F)CC3)c[nH]1 -US06737435B1,2,COC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1>>COC(=O)c1cc2cc(OCc3ccccc3)ccc2n1S(=O)(=O)c1ccc(Cl)c(Cl)c1 -US20120230951A1,2,CNOC.O=C(O)c1cnc2cc(Br)ccc2c1>>CON(C)C(=O)c1cnc2cc(Br)ccc2c1 -US20100222328A1,6,CC(C)(C)OC(=O)N1CCC[C@H]1CNC(=O)C(F)(F)F>>O=C(NC[C@@H]1CCCN1)C(F)(F)F -US05817652,1,CCC(N)(CO)CS(=O)(=O)c1ccccc1C(=O)c1ccccc1>>CCC1(CO)CS(=O)(=O)c2ccccc2C(c2ccccc2)=N1 -US20120289474A1,3,CCn1nnc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(Br)cc32)n1.OB(O)c1cccc(F)c1F>>CCn1nnc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4cccc(F)c4F)cc32)n1 -US07109339B2,4,NNc1ccccc1I.O=C1CCNCC1>>Ic1cccc2c3c([nH]c12)CCNC3 -US20080090863A1,1,N[C@@H]1CC[C@H](NCc2ccccc2)CC1.[O-][n+]1c(Br)cccc1Br>>[O-][n+]1c(Br)cccc1N[C@@H]1CC[C@H](NCc2ccccc2)CC1 -US20110105475A1,6,CCOC(=O)c1cc2c(C)c(N3CCN(C(=O)OC(C)(C)C)CC3)ccc2o1>>CCOC(=O)c1cc2c(C)c(N3CCNCC3)ccc2o1 -US05190928,9,NC(=O)c1cccc2nnsc12>>N#Cc1cccc2nnsc12 -US04212865,2,CS(=O)(=O)Cl.Nc1cccc2c(-c3ccccc3)c([N+](=O)[O-])oc12>>CS(=O)(=O)Nc1cccc2c(-c3ccccc3)c([N+](=O)[O-])oc12 -US20120214785A1,3,C#Cc1ccc(CC(C)NC(C)=O)cc1.COc1ccc(Br)c(OC)c1>>COc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)c(OC)c1 -US20150274704A1,6,CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CC2CN(C(=O)OC(C)(C)C)CC2C1>>CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CC2CNCC2C1 -US07015218B1,2,Cc1c(C(=O)Cl)cnn1-c1ccc(Cl)cc1.N#Cc1cc(N)ccc1CN1CCC(N2CCOCC2)CC1>>Cc1c(C(=O)Nc2ccc(CN3CCC(N4CCOCC4)CC3)c(C#N)c2)cnn1-c1ccc(Cl)cc1 -US07012089B2,7,CN1CCc2c(Cl)ccc3c4c(n(c23)CC1)CCC4>>CN1CCc2c(Cl)ccc3c2N(CC1)C1CCCC31 -US08362236B2,1,CC(C)(C)OC(=O)NCCS.COC(=O)c1cc(-c2cc(Cl)nc(N)n2)c(C)cc1OC>>COC(=O)c1cc(-c2cc(SCCNC(=O)OC(C)(C)C)nc(N)n2)c(C)cc1OC -US05302718,3,C#Cc1ccc(O)c(C(=O)OCC)c1.Cc1cccnc1NS(=O)(=O)c1cccc(I)c1>>CCOC(=O)c1cc(C#Cc2cccc(S(=O)(=O)Nc3ncccc3C)c2)ccc1O -US20150274767A1,8,CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](n2cc(I)c3c(N)ncnc32)OC1(CO)CO>>CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](n2cc(I)c3c(N)ncnc32)O[C@]1(C=O)CO -US20080064729A1,1,CNC(=O)c1cc(Cl)ccn1.Oc1cccc(I)c1>>CNC(=O)c1cc(Oc2cccc(I)c2)ccn1 -US06087379,6,CCOC(=O)/C=C1\CN(C(C(=O)C2CC2)c2ccccc2F)CCC1S>>O=C(O)/C=C1\CN(C(C(=O)C2CC2)c2ccccc2F)CCC1S -US20060229336A1,2,COC(=O)c1ccc(C(=O)O)cc1.Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCNCC1>>COC(=O)c1ccc(C(=O)N2CCC(CCN3C4CCC3CC(n3c(C)nc5ccccc53)C4)(c3ccccc3)CC2)cc1 -US06617358B1,6,CCOC(=O)CC(c1cccc(F)c1)c1cccc(F)c1>>O=C(O)CC(c1cccc(F)c1)c1cccc(F)c1 -US20140142099A1,6,CC(C)(C)OC(=O)N1CCC(n2c(=O)n(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1n(-c1ccc(Oc3ccccc3)cc1)c(=O)n2C1CCNC1 -US20120184548A1,6,COCCOc1cc2cc(C(=O)Nc3cc(C(=O)OC)ccc3Cl)c(=O)[nH]c2cc1OC>>COCCOc1cc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2cc1OC -US20040014968A1,2,Nc1ccncn1.O=C(O)[C@H](CC1CCCC1)c1ccc(Cl)c(Cl)c1>>O=C(Nc1ccncn1)[C@H](CC1CCCC1)c1ccc(Cl)c(Cl)c1 -US08916599B2,2,CC(=O)O.Nc1ccc(C(=O)O)c(F)c1>>CC(=O)Nc1ccc(C(=O)O)c(F)c1 -US05693827,2,CC(C)OC(=O)c1cc(N)ccc1Cl.CC1=C(C(=O)O)SCCS1>>CC1=C(C(=O)Nc2ccc(Cl)c(C(=O)OC(C)C)c2)SCCS1 -US20050234096A1,7,COc1ccc2c(c1)C(C)=NCC2>>COc1ccc2c(c1)C(C)NCC2 -US20140142085A1,6,CC(C)(C)OC(=O)N1CCc2c(c(C(F)(F)F)nn2CC(=O)N[C@@H](Cc2cc(F)cc(F)c2)c2ncccc2-c2ccc(F)c(C(N)=O)c2)C1>>NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCNC3)ccc1F -US07858640B2,6,COC(=O)C(C)Oc1ccc(F)c2nc(OC(F)F)c(Cc3ccc(Cl)cc3Cl)c(C)c12>>Cc1c(Cc2ccc(Cl)cc2Cl)c(OC(F)F)nc2c(F)ccc(OC(C)C(=O)O)c12 -US20130252890A1,1,CC(C)(O)CNCCCS(=O)(=O)CCC(F)(F)F.Oc1ccc2c(c1)CCCC(c1ccc(F)c(F)c1)=C2CCCCCCBr>>CC(C)(O)CN(CCCCCCC1=C(c2ccc(F)c(F)c2)CCCc2cc(O)ccc21)CCCS(=O)(=O)CCC(F)(F)F -US08426473B2,3,CC(C)(C)[Si](C)(C)Oc1cc(Br)cc(Br)c1.CN(C)C=O>>CC(C)(C)[Si](C)(C)Oc1cc(Br)cc(C=O)c1 -US20150183775A1,1,NS(=O)(=O)c1ccc(F)c(Cl)c1.OCC1(F)CCOCC1>>NS(=O)(=O)c1ccc(OCC2(F)CCOCC2)c(Cl)c1 -US04207327,2,CC(C)N1CC(N)CN1C.COc1cc(N)c(Cl)cc1C(=O)O>>COc1cc(N)c(Cl)cc1C(=O)NC1CN(C)N(C(C)C)C1 -US20140018326A1,7,CC(C)(C)OC(=O)N[C@@H](Cc1cccc([N+](=O)[O-])c1)C(=O)O>>CC(C)(C)OC(=O)N[C@H](CO)Cc1cccc([N+](=O)[O-])c1 -US20140249132A1,7,CCOc1c(C(C)=O)cc(Cl)c(C#N)c1Br>>CCOc1c(C(C)O)cc(Cl)c(C#N)c1Br -US05929067,7,CCOC(=O)C=CC(Cc1ccc2ccccc2c1)N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCOC(=O)CCC(Cc1ccc2ccccc2c1)N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20090029976A1,2,CC(C)N1CCC(Oc2ccc3cc(C(=O)O)sc3c2)CC1.FC1(F)CCNCC1>>CC(C)N1CCC(Oc2ccc3cc(C(=O)N4CCC(F)(F)CC4)sc3c2)CC1 -US06117359,2,CC(=O)Cl.O=C(O)C=Cc1ccc(O)cc1>>CC(=O)Oc1ccc(C=CC(=O)O)cc1 -US06458845B1,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccccc1C(=O)O>>Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)O)cc1 -US20140343049A1,1,N#Cc1cc(I)ccc1F.c1nc[nH]n1>>N#Cc1cc(I)ccc1-n1cncn1 -US20130210625A1,1,C=Cc1cc(C)cc(C)c1CC(=O)Cl.COC(=O)C1(NO)CCN(OC)CC1>>C=Cc1cc(C)cc(C)c1CC(=O)N(O)C1(C(=O)OC)CCN(OC)CC1 -US20110136763A1,1,CCOC(=O)CC1OB(O)c2cc(O)cc(F)c21.Clc1cnccn1>>CCOC(=O)CC1OB(O)c2cc(Oc3cnccn3)cc(F)c21 -US06350907B1,3,C=CC[C@H](CC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@H](C)c1ccccc1)C(C)(C)C.Cc1cc(Br)ccc1-c1ccccc1>>Cc1cc(/C=C/C[C@H](CC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@H](C)c2ccccc2)C(C)(C)C)ccc1-c1ccccc1 -US20120015908A1,6,COc1cc2c(cc1OCc1ccccc1)N=C(c1ccccc1F)CC2=O>>COc1cc2c(cc1O)N=C(c1ccccc1F)CC2=O -US20040058907A1,6,CC(C)(C)OC(=O)N1CCOC(CNC(=O)Nc2ccc(Cl)cc2)C1>>O=C(NCC1CNCCO1)Nc1ccc(Cl)cc1 -US20030232842A1,1,C1CCNCC1.COC(=O)C1=C(CBr)NC(c2ncc(F)cc2F)=N[C@H]1c1ccc(F)cc1Cl>>COC(=O)C1=C(CN2CCCCC2)NC(c2ncc(F)cc2F)=N[C@H]1c1ccc(F)cc1Cl -US05714496,3,COc1ccc(Br)cn1.OB(O)c1ccc(Br)cc1>>COc1ccc(-c2ccc(Br)cc2)cn1 -US05294629,1,CCOCCCl.Sc1nc2cc(Cl)ccc2s1>>CCOCCSc1nc2cc(Cl)ccc2s1 -US20070054918A1,1,C=CCN1CCNCC1.CC(C)c1ccc(S(=O)(=O)Nc2cc(Cl)ncn2)cc1>>C=CCN1CCN(c2cc(NS(=O)(=O)c3ccc(C(C)C)cc3)ncn2)CC1 -US20090324581A1,6,Cc1cccc2c1N(C(=O)OC(C)(C)C)CC2>>Cc1cccc2c1NCC2 -US08471005B2,1,CSc1ncc2ccc(C=O)n2n1.Nc1ccccc1>>CSc1ncc2ccc(CNc3ccccc3)n2n1 -US20020198197A1,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1.COc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>COc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3nncc3COC3CCCCO3)c2)cc1C(F)(F)F -US20040176593A1,1,Cc1cc(Cl)c(NC(=O)CBr)c(Cl)n1.OCCN1CCNCC1>>Cc1cc(Cl)c(NC(=O)CN2CCN(CCO)CC2)c(Cl)n1 -US20150209336A1,2,CCCCOC(=O)c1nc(-c2ccccn2)c2snc(C)c2c1O.NCC(=O)O>>Cc1nsc2c(-c3ccccn3)nc(C(=O)NCC(=O)O)c(O)c12 -US08017603B2,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=CC12CCC(c3ccccc3)(CC1)CC2>>COC=CC12CCC(c3ccccc3)(CC1)CC2 -US04346101,3,O=C1CCC(=O)CC1.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>O=C1CCC(=Cc2ccccc2)CC1 -US20090306107A1,6,Nc1ncnc2c1c(-c1cccc(NC(=O)c3ccccc3)c1)c1n2CCCC1>>Nc1cccc(-c2c3n(c4ncnc(N)c24)CCCC3)c1 -US07232834B2,6,COC(=O)CC1CN(CCSc2cc(F)ccc2F)CCC1CCC(=O)c1c(F)cnc2ccc(OC)cc12>>COc1ccc2ncc(F)c(C(=O)CCC3CCN(CCSc4cc(F)ccc4F)CC3CC(=O)O)c2c1 -US04728646,1,C1CNCCN1.CN(c1ccccc1)c1ncnc2c(N3CCOCC3)nc(Cl)nc12>>CN(c1ccccc1)c1ncnc2c(N3CCOCC3)nc(N3CCNCC3)nc12 -US20090181948A1,1,CC(C)(C)[Si](C)(C)OCCCBr.N#CC(C#N)=C1Nc2ccccc2N1>>CC(C)(C)[Si](C)(C)OCCCN1C(=C(C#N)C#N)Nc2ccccc21 -US05635197,1,CN1C(=O)CC[C@]2(C)c3ccc(S)cc3CC[C@@H]12.Clc1nc2c(-c3ccccc3)cccc2s1>>CN1C(=O)CC[C@]2(C)c3ccc(Sc4nc5c(-c6ccccc6)cccc5s4)cc3CC[C@@H]12 -US20110230462A1,2,C[C@@H](NC(=O)OC(C)(C)C)C(=O)O.N#CC1CNC1>>C[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CC(C#N)C1 -US20070060601A1,2,CCOC(=O)C1=C(N)CCCC1.O=C(Cl)c1ccccc1Cl>>CCOC(=O)C1=C(NC(=O)c2ccccc2Cl)CCCC1 -US20140213586A1,1,CC(C)Oc1cncc(N)c1.O=Cc1ccccc1>>CC(C)Oc1cncc(N=Cc2ccccc2)c1 -US20110207728A1,6,COC(=O)c1cccc(=O)n1CC(=O)c1ccc(Cl)cc1>>O=C(Cn1c(C(=O)O)cccc1=O)c1ccc(Cl)cc1 -US20100041891A1,9,CCOC(=O)c1cccc(-c2cccc3sc(Cc4ccc(F)c(F)c4)cc23)c1.N>>NC(=O)c1cccc(-c2cccc3sc(Cc4ccc(F)c(F)c4)cc23)c1 -US06329369B1,6,[N-]=[N+]=NCC(CC1CCc2ccccc2C1)N1C(=O)c2ccccc2C1=O>>[N-]=[N+]=NCC(N)CC1CCc2ccccc2C1 -US20100112090A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(Cl)c(N)cc1OCc1c(OC)ccc(F)c1F>>COc1cc(Cl)c(NC(=O)OC(C)(C)C)cc1OCc1c(OC)ccc(F)c1F -US20130005721A1,4,C#CC(CC)(OC(=O)c1ccc([N+](=O)[O-])cc1)C(F)(F)F.CCOC(=O)c1cc2cc(CN=[N+]=[N-])ccn2c1C(C)C>>CCOC(=O)c1cc2cc(Cn3cc(C(CC)(OC(=O)c4ccc([N+](=O)[O-])cc4)C(F)(F)F)nn3)ccn2c1C(C)C -US20150099777A1,1,CI.O=Cc1cc(Br)c(-c2ccc(F)cc2)c(F)c1O>>COc1c(C=O)cc(Br)c(-c2ccc(F)cc2)c1F -US20050143452A1,3,Cc1ccc(S(=O)(=O)OCC2Cc3cc(F)cc(Br)c3O2)cc1.OB(O)c1ccccc1Cl>>Cc1ccc(S(=O)(=O)OCC2Cc3cc(F)cc(-c4ccccc4Cl)c3O2)cc1 -US20150031686A1,1,COc1cc(CN)ccc1-c1cnco1.Cc1ccc(C=O)s1>>COc1cc(CNCc2ccc(C)s2)ccc1-c1cnco1 -US20020160996A1,2,COc1ccc(C(=O)Cl)cc1.Cc1oc2c(C)c(C)c(N)c(C)c2c1-c1ccc(F)cc1>>COc1ccc(C(=O)Nc2c(C)c(C)c3oc(C)c(-c4ccc(F)cc4)c3c2C)cc1 -US05753664,1,Cn1c(=O)c2[nH]cnc2n(C)c1=O.O=C(c1ccc(CBr)cc1)c1ccccc1Cl>>Cn1c(=O)c2c(ncn2Cc2ccc(C(=O)c3ccccc3Cl)cc2)n(C)c1=O -US06140351,1,CNC.COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CCl)c1Cl>>COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)C)c1Cl -US08598154B2,6,COC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2>>O=C(O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2 -US20130045962A1,1,CCC1(OS(C)(=O)=O)CN(C(c2ccccc2)c2ccccc2)C1.CNC>>CCC1(N(C)C)CN(C(c2ccccc2)c2ccccc2)C1 -US05250109,6,C=C(C)C(=O)O[Si](C)(C)C>>C=C(C)C(=O)O -US05654301,2,C=CC(NC(C)=O)C(=O)O.NCc1ccccc1>>C=CC(NC(C)=O)C(=O)NCc1ccccc1 -US05194610,1,CNC.NC1N=C(Cl)N=C(F)N1OC(F)F>>CN(C)C1=NC(Cl)=NC(N)N1OC(F)F -US20120059002A1,6,CCOC(=O)c1cc(OC(C)C)cc(OC(C)C)c1>>CC(C)Oc1cc(OC(C)C)cc(C(=O)O)c1 -US20060166985A1,6,COCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCOCC1>>COCC[C@H](N)C(=O)N1CCOCC1 -US20140323470A1,2,Cc1ccc(-c2[nH]c(C(C)(C)C)nc2N)cc1.O=C(Cl)OCC(Cl)(Cl)Cl>>Cc1ccc(-c2[nH]c(C(C)(C)C)nc2NC(=O)OCC(Cl)(Cl)Cl)cc1 -US08324385B2,2,CC(C)(C)c1cccc(N)c1.Cc1cc(Br)ccc1C(=O)O>>Cc1cc(Br)ccc1C(=O)Nc1cccc(C(C)(C)C)c1 -US20060094764A1,9,N#C[Cu].N#Cc1c(NC(=O)C2CCCCC2)sc(-c2ccccc2)c1Br>>N#Cc1c(NC(=O)C2CCCCC2)sc(-c2ccccc2)c1C#N -US03966732,6,CC(=O)OCCOc1cnc(-c2ncc([N+](=O)[O-])n2C)nc1>>Cn1c([N+](=O)[O-])cnc1-c1ncc(OCCO)cn1 -US08940771B2,9,CCCCOC(=O)[C@@H]1C[C@H](N(C)C)CN1.N>>CN(C)[C@@H]1CN[C@H](C(N)=O)C1 -US20120077812A1,1,CCc1cnc(Cl)nc1.CS(=O)(=O)c1ccc(-c2ccc(OCC3CCNCC3)cc2)cc1>>CCc1cnc(N2CCC(COc3ccc(-c4ccc(S(C)(=O)=O)cc4)cc3)CC2)nc1 -US20060100431A1,6,COC1(OC)CN(C(=O)c2ccccc2)[C@@H]2CCN(C(=O)OCc3ccccc3)[C@@H]21>>COC1(OC)CN(C(=O)c2ccccc2)[C@@H]2CCN[C@@H]21 -US20060122168A1,6,CCOC(=O)C(C(O)CCOCc1ccccc1)N(Cc1ccccc1)Cc1ccccc1>>O=C(O)C(C(O)CCOCc1ccccc1)N(Cc1ccccc1)Cc1ccccc1 -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CNC[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CS(=O)(=O)CC(=O)O>>CN(C(=O)N(C)[C@@H]1CN(C(=O)CS(C)(=O)=O)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20110275622A1,1,CC(C)(C)[Si](C)(C)OCCCCCCBr.OC1CCN(Cc2ccccc2)CC1>>CC(C)(C)[Si](C)(C)OCCCCCCOC1CCN(Cc2ccccc2)CC1 -US20130079383A1,9,COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)NC(=O)C1(CCN=[N+]=[N-])CCCC1>>COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)NC(=O)C1(CCN)CCCC1 -US05663189,2,Cc1c(N=C=S)ccc2c1OCC2.NCCN>>Cc1c(NC(=S)NCCN)ccc2c1OCC2 -US20110071194A1,7,COc1cc(C(=O)[C@@H](C)NC(=O)OC(C)(C)C)ccc1SC>>COc1cc(C(O)[C@@H](C)NC(=O)OC(C)(C)C)ccc1SC -US08222251B2,3,C[C@@H]1CN(C(=O)c2ccccc2)CCN1c1nnc(Cl)c2cccnc12.OB(O)c1ccc(Cl)cc1F>>C[C@@H]1CN(C(=O)c2ccccc2)CCN1c1nnc(-c2ccc(Cl)cc2F)c2cccnc12 -US08481540B2,3,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1-n1ncc2cc(C(C)(C)C)cc(F)c2c1=O.Cn1nc(Cl)cc(Nc2cc3n(n2)CCN(C2COC2)C3)c1=O>>CC(=O)OCc1c(-c2cc(Nc3cc4n(n3)CCN(C3COC3)C4)c(=O)n(C)n2)cccc1-n1ncc2cc(C(C)(C)C)cc(F)c2c1=O -US20100197591A1,7,CC(C)(C(=O)O)c1ccc(Br)cc1>>CC(C)(CO)c1ccc(Br)cc1 -US20040044008A1,6,CCOC(=O)CN1CCN(c2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)CC1>>O=C(O)CN1CCN(c2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)CC1 -US08093240B2,1,C[O-].Nc1cc(Cl)ccc1[N+](=O)[O-]>>COc1ccc([N+](=O)[O-])c(N)c1 -US20040058990A1,1,NNC(=S)Nc1cccc(C(=O)O)c1.O=Cc1c(O)ccc2ccccc12>>O=C(O)c1cccc(NC(=S)NN=Cc2c(O)ccc3ccccc23)c1 -US20090197880A1,4,N#Cc1ccc(-c2cc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)cc1.[N-]=[N+]=[N-]>>Fc1cccc(-c2nc3cnn(Cc4cc(-c5ccc(-c6nnn[nH]6)cc5)no4)cc-3n2)c1F -US20070129372A1,9,O=c1ccn2nc(Cl)ccc2c1-c1c(F)cccc1F.[NH4+]>>Nc1ccc2c(-c3c(F)cccc3F)c(=O)ccn2n1 -US03950380,7,O=C(O)c1cc(SCc2ccsc2)c(-c2ccccc2)c([N+](=O)[O-])c1>>Nc1cc(C(=O)O)cc(SCc2ccsc2)c1-c1ccccc1 -US20140163077A1,1,Nc1ccccc1.O=Cc1cccc(-c2ccncc2)c1>>c1ccc(NCc2cccc(-c3ccncc3)c2)cc1 -US05216026,2,CC(C)S(N)(=O)=O.O=C=Nc1ccc(Cl)c(Cl)c1>>CC(C)S(=O)(=O)NC(=O)Nc1ccc(Cl)c(Cl)c1 -US08097733B2,9,COc1ccc(CBr)cc1Br.[C-]#N>>COc1ccc(CC#N)cc1Br -US04064258,7,CC12CCC(CC#N)(CC1)CC2>>CC12CCC(CCN)(CC1)CC2 -US20140163026A1,9,BrCc1ccc(Br)cn1.[C-]#N>>N#CCc1ccc(Br)cn1 -US20150038438A1,3,CON(C)C(=O)Cc1ccc2c(c1)OCO2.C[Mg+]>>CC(=O)Cc1ccc2c(c1)OCO2 -US04521426,7,O=[N+]([O-])c1ccc(Oc2cccc3ccccc23)nc1>>Nc1ccc(Oc2cccc3ccccc23)nc1 -US20070015743A1,1,Fc1cccc2ncnc(Cl)c12.Nc1ccc(O)c(Cl)c1>>Oc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl -US06143779,3,CCCCCOc1ccc(C=O)cc1OC.O=C1COc2cc(O)ccc21>>CCCCCOc1ccc(C=C2Oc3cc(O)ccc3C2=O)cc1OC -US06329389B1,6,CCOC(=O)CCc1nc(-c2cc3ccccc3o2)cs1>>O=C(O)CCc1nc(-c2cc3ccccc3o2)cs1 -US20060223826A1,2,COc1ccc(CN(C)C)cc1NC(=O)[C@H](NC(=O)N1CCNCC1)[C@@H](C)c1c[nH]c2ccccc12.O=C(O)c1ccc(F)cc1>>COc1ccc(CN(C)C)cc1NC(=O)[C@H](NC(=O)N1CCN(C(=O)c2ccc(F)cc2)CC1)[C@@H](C)c1c[nH]c2ccccc12 -US07994203B2,3,CN(C)C=O.Cc1cc2oc(C)c(-c3ccc(Cl)cc3Cl)n2n1>>Cc1nn2c(-c3ccc(Cl)cc3Cl)c(C)oc2c1C=O -US07635715B2,6,CCOC(=O)C(C)(C)c1ccccc1Cl>>CC(C)(C(=O)O)c1ccccc1Cl -US07968550B2,6,COc1ccc(C2(C(=O)Nc3ccc(N4CCC(NCC(C)=O)C4)cc3)CC2)cc1>>CC(=O)CNC1CCN(c2ccc(NC(=O)C3(c4ccc(O)cc4)CC3)cc2)C1 -US08183262B2,7,Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc([N+](=O)[O-])c3)n2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc(N)c3)n2)n1 -US20130295261A1,2,N[C@H]1CO[C@@H]2[C@@H](NC(=O)C3CC3)CO[C@H]12.O=C(O)C#Cc1ccccc1>>O=C(C#Cc1ccccc1)N[C@H]1CO[C@@H]2[C@@H](NC(=O)C3CC3)CO[C@H]12 -US20050256107A1,2,CC(C)(NC(=O)c1ccc(Br)s1)C(=O)O.CN1CCCCN1c1ccc(N)cc1Cl>>CN1CCCCN1c1ccc(NC(=O)C(C)(C)NC(=O)c2ccc(Br)s2)cc1Cl -US20070254901A1,8,CCSc1ncc2cc(-c3ccccc3)c(-c3ccc(C=O)cc3)nc2n1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)c1ncc2cc(-c3ccccc3)c(-c3ccc(C=O)cc3)nc2n1 -US05670641,6,COc1ccc(Br)c(-n2c(=O)[nH]c(=O)n(C)c2=O)c1>>Cn1c(=O)[nH]c(=O)n(-c2cc(O)ccc2Br)c1=O -US20050131014A1,1,BrCC1CCCCC1.O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(O)c1>>O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(OCC2CCCCC2)c1 -US20150266866A1,1,CI.COC(=O)c1cc(C(O)c2cncnc2)cc2cccnc12>>COC(=O)c1cc(C(OC)c2cncnc2)cc2cccnc12 -US08586603B2,2,CCCN[C@H]1CCc2cccc(OC)c2C1.O=C(O)Cc1cccs1>>CCCN(C(=O)Cc1cccs1)[C@H]1CCc2cccc(OC)c2C1 -US20070078267A1,1,CCCCCC(C)Br.Oc1ccc(Br)cc1>>CCCCCC(C)Oc1ccc(Br)cc1 -US07790709B2,1,CN.O=Cc1cc2cnccc2s1>>CNCc1cc2cnccc2s1 -US20060257987A1,3,COC(=O)CCc1ccc(OCC[C@H](C)Oc2ccc(Cl)cc2Br)cc1C.OB(O)c1ccccc1F>>COC(=O)CCc1ccc(OCC[C@H](C)Oc2ccc(Cl)cc2-c2ccccc2F)cc1C -US07094789B2,6,Cc1cncc2cccc(NC3CCN(C(=O)OC(C)(C)C)CC3)c12>>Cc1cncc2cccc(NC3CCNCC3)c12 -US05962473,2,CC(=O)Cl.CN1CCC(c2c[nH]c3ccc(N)cc23)CC1>>CC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2c1 -US20100249163A1,6,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(OC)c2cc(F)cc(F)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)C2CNCCC2(OC)c2cc(F)cc(F)c2)C2CC2)cc(OCCOC)c1 -US20070060607A1,1,COc1ccc(CCl)cc1.Oc1cccc(O)c1>>COc1ccc(COc2cccc(O)c2)cc1 -US20130231327A1,1,Brc1ccncc1.CC(C)(C)OC(=O)N1CCC2(CCNCC2)C1>>CC(C)(C)OC(=O)N1CCC2(CCN(c3ccncc3)CC2)C1 -US20150194612A1,3,Cc1ccnc(Cl)c1.OB(O)c1cccnc1>>Cc1ccnc(-c2cccnc2)c1 -US20090143354A1,1,CC(C)(C)OC(=O)CN.O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(Cl)ccc12>>CC(C)(C)OC(=O)CNc1ccc2c(NC(=O)CC3CCCCC3)c(Cl)ccc2n1 -US20140303187A1,7,CC(=O)Nc1ncc([N+](=O)[O-])cn1>>CC(=O)Nc1ncc(N)cn1 -US20070281916A1,1,C1CSCCN1.Fc1ccc(C2=NOC(COc3ccon3)C2)cc1F>>Fc1cc(C2=NOC(COc3ccon3)C2)ccc1N1CCSCC1 -US07951824B2,3,Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C(=O)Nc2ccn(C)n2)n1.N#Cc1cc(Br)ccn1>>Cc1cc(-c2ccnc(C#N)c2)cc(C(=O)Nc2ccn(C)n2)n1 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3sc(Cl)cc23)cc1OC.c1cn[nH]c1>>COc1ccc(CNc2nc(-n3cccn3)nc3sc(Cl)cc23)cc1OC -US04636516,8,CSc1nc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cs1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1nc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cs1 -US20050165058A1,6,CCOC(=O)c1cc(OCCc2ccc(Cl)cc2Cl)c2c(c1)OCO2>>O=C(O)c1cc(OCCc2ccc(Cl)cc2Cl)c2c(c1)OCO2 -US20120289505A1,2,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(N)cc3)ccc2C1=O.FC(F)(F)c1cccc(N=C=S)c1>>COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=S)Nc4cccc(C(F)(F)F)c4)cc3)ccc2C1=O -US06096895,1,COC(=O)c1cocc1-n1c(Cl)nn(C)c1=O.C[O-]>>COC(=O)c1cocc1-n1c(OC)nn(C)c1=O -US20140187422A1,1,C#CCBr.OC(/C=C/c1ccccc1)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl>>C#CCOC(/C=C/c1ccccc1)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl -US20090186875A1,1,NCCCc1nc(Cl)nc2c1SCC2.c1ccc(N2CCNCC2)cc1>>NCCCc1nc(N2CCN(c3ccccc3)CC2)nc2c1SCC2 -US06403633B2,4,Cc1sc(C(=O)OC(C)C)cc1C(=O)CBr.NC(=S)Nc1ccccc1>>Cc1sc(C(=O)OC(C)C)cc1-c1csc(Nc2ccccc2)n1 -US20150005293A1,6,CCOC(=O)c1cn(-c2ncccn2)nc1OC>>COc1nn(-c2ncccn2)cc1C(=O)O -US07432275B2,6,COC(=O)C1CCCN1CCOc1cc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)ccc1C(C)(C)C>>CC(C)(C)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1OCCN1CCCC1C(=O)O -US20120252781A1,6,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN(C)C(=O)OC(C)(C)C)c1nnc(C)n1-2>>CNCCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 -US08030327B2,1,C[C@H](O)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1Cl.Cc1c(-c2cnc3ccccn23)sc(C(=O)O)c1O>>Cc1c(-c2cnc3ccccn23)sc(C(=O)O)c1O[C@H](C)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1Cl -US20090136448A1,7,O=[N+]([O-])c1ccc2cc(-c3ccc(Br)cc3)oc2c1>>Nc1ccc2cc(-c3ccc(Br)cc3)oc2c1 -US04609494,6,CCOC(=O)C1=C(C)NC(=O)N(C(C)=O)C1c1cc([N+](=O)[O-])ccc1OC(C)=O>>CCOC(=O)C1=C(C)NC(=O)N(C(C)=O)C1c1cc([N+](=O)[O-])ccc1O -US20050277670A1,1,CC(C)(C)OC(=O)N1CCC(C(O)c2ccc(Br)cc2)CC1.Clc1cccc(Cl)n1>>CC(C)(C)OC(=O)N1CCC(C(Oc2cccc(Cl)n2)c2ccc(Br)cc2)CC1 -US20060084690A1,2,CO.O=C(O)CCc1cnoc1-c1ccc(Cl)c(Cl)c1>>COC(=O)CCc1cnoc1-c1ccc(Cl)c(Cl)c1 -US20030083359A1,1,N[C@H]1CCCc2ccccc21.O=Cc1cc(F)cc(F)c1>>Fc1cc(F)cc(CN[C@H]2CCCc3ccccc32)c1 -US20040110767A1,1,Nc1ccc(OCCN2CCCC2)cc1.O=Cc1ccc(OC2CCCCO2)cc1Cl>>Clc1cc(OC2CCCCO2)ccc1CNc1ccc(OCCN2CCCC2)cc1 -US05597848,6,COC(=O)CCCc1ccc(C(Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)cc1>>O=C(O)CCCc1ccc(C(Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)cc1 -US20100324057A1,1,CCCc1cccc(O)c1.O=Cc1ccc(F)cc1Cl>>CCCc1cccc(Oc2ccc(C=O)c(Cl)c2)c1 -US20110136801A1,1,CCC(Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CCl)c1)C(=O)OC.CCNCC>>CCC(Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1)C(=O)OC -US20100240617A1,6,CCCCCCCCc1ccc2c(c1)CCC(C(C)(C(=O)OCC)C(=O)OCC)C2>>CCCCCCCCc1ccc2c(c1)CCC(C(C)(C(=O)O)C(=O)OCC)C2 -US05244889,1,BrCc1ccccc1.CC(=O)SCC1CCCCCCCSC[C@@H](C(=O)O)NC1=O>>CC(=O)SCC1CCCCCCCSC[C@@H](C(=O)OCc2ccccc2)NC1=O -US06414005B1,6,CCSC(=N)Nc1ccc(-n2cccn2)c(CNC(=O)OC(C)(C)C)c1C>>CCSC(=N)Nc1ccc(-n2cccn2)c(CN)c1C -US07598264B2,2,COc1cnc(N)c2c1C(=O)N(Cc1ccc(F)cc1)CC2.CS(=O)(=O)Cl>>COc1cnc(NS(C)(=O)=O)c2c1C(=O)N(Cc1ccc(F)cc1)CC2 -US20140142083A1,1,CI.COC(=O)c1cc(Br)cc(NC2CCC(NC(=O)OC(C)(C)C)CC2)c1C>>COC(=O)c1cc(Br)cc(N(C)C2CCC(NC(=O)OC(C)(C)C)CC2)c1C -US20120214803A1,2,Cc1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1.Nc1ccc(Cl)c2cccnc12>>Cc1ccc(S(=O)(=O)Nc2ccc(Cl)c3cccnc23)c([N+](=O)[O-])c1 -US05861407,1,C(=C/c1ccc2[nH]ccc2c1)\c1ccncc1.CI>>Cn1ccc2cc(/C=C/c3ccncc3)ccc21 -US08569535B2,3,CCOC(=O)C1(NC(=O)c2cccc(C)c2I)Cc2ccc(F)cc2C1.OB(O)C1=CCCC1>>CCOC(=O)C1(NC(=O)c2cccc(C)c2C2=CCCC2)Cc2ccc(F)cc2C1 -US20110144164A1,3,C[Sn](C)(C)C.Cc1c(C(=O)N[C@H](c2cccc(F)c2)C2CCC2)c(C)n(-c2ccccc2)c(=O)c1Br>>Cc1c(C(=O)N[C@H](c2cccc(F)c2)C2CCC2)c(C)n(-c2ccccc2)c(=O)c1C -US08338437B2,5,O=Cc1cccc(-n2nc(C(F)(F)F)cc2-c2ccco2)c1.OCCCO>>FC(F)(F)c1cc(-c2ccco2)n(-c2cccc(C3OCCCO3)c2)n1 -US20130324501A1,1,CC(C)(C)OC(=O)c1ccc(NS(C)(=O)=O)s1.ClCCN1CCOCC1>>CC(C)(C)OC(=O)c1ccc(N(CCN2CCOCC2)S(C)(=O)=O)s1 -US20130303538A1,2,CCN(CC)C(=O)CCC(=O)O.COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1>>CCN(CC)C(=O)CCC(=O)O[C@@]1(C#Cc2cccc(C)c2)CCC[C@@H]2[C@H]1CCN2C(=O)OC -US08288536B2,1,BrCc1cccc(Br)c1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(Br)c2)CC1 -US20110028501A1,7,Cc1nnn(-c2ccc([N+](=O)[O-])cc2)n1>>Cc1nnn(-c2ccc(N)cc2)n1 -US20080261973A1,1,CS(=O)(=O)Nc1cccc(Nc2nc(Cl)c3cc[nH]c3n2)c1.NC1CCCC1>>CS(=O)(=O)Nc1cccc(Nc2nc(NC3CCCC3)c3cc[nH]c3n2)c1 -US07557112B2,4,N#CCC1CCN(c2nc(-c3cc(F)c(Cl)cc3F)nc3ccsc23)CC1.[N-]=[N+]=[N-]>>Fc1cc(-c2nc(N3CCC(Cc4nnn[nH]4)CC3)c3sccc3n2)c(F)cc1Cl -US07858613B2,2,O=C1c2ccccc2SCCC1CO.O=C=Nc1ccc(Br)cc1>>O=C(Nc1ccc(Br)cc1)OCC1CCSc2ccccc2C1=O -US20150252036A1,3,CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(Br)cc1O>>CC=Cc1ccc(Br)cc1O -US20090318385A1,6,CCOC(=O)c1c(COC2CCCCO2)nn2c(OC)ccc(CO)c12>>COc1ccc(CO)c2c(C(=O)O)c(COC3CCCCO3)nn12 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.CCN>>CC#CCOc1cc(NCC)ncn1 -US20090149445A1,9,NO.O=Cc1ccccc1C=C1c2ccccc2CCc2ccccc21>>ON=Cc1ccccc1C=C1c2ccccc2CCc2ccccc21 -US20100256097A1,1,CC(C)(O)c1ccc(-c2cc(C(N)=O)c(Nc3cccc(CO)n3)s2)c(F)c1.COCCBr>>COCCOCc1cccc(Nc2sc(-c3ccc(C(C)(C)O)cc3F)cc2C(N)=O)n1 -US07915433B2,1,N[C@H]1CO[C@@H](C(c2ccccc2)c2ccccc2)C[C@@H]1O.O=Cc1ccc2[nH]ccc2c1>>O[C@H]1C[C@H](C(c2ccccc2)c2ccccc2)OC[C@@H]1NCc1ccc2[nH]ccc2c1 -US20110046127A1,2,CCOC(=O)c1cccc(N)c1.COc1ccc(CNc2cc(C)c3ncc(C(=O)O)n3n2)cc1>>CCOC(=O)c1cccc(NC(=O)c2cnc3c(C)cc(NCc4ccc(OC)cc4)nn23)c1 -US20090042949A1,6,CCOC(=O)c1c(Cl)c2cc(Oc3ccc(C(F)(F)F)cc3)ccc2n1-c1ccc(OC(C)C)cc1>>CC(C)Oc1ccc(-n2c(C(=O)O)c(Cl)c3cc(Oc4ccc(C(F)(F)F)cc4)ccc32)cc1 -US06180629B2,2,Nn1nc(-c2ccccn2)c2c(F)ccc(F)c2c1=O.O=C(Cl)c1ccccc1>>O=C(Nn1nc(-c2ccccn2)c2c(F)ccc(F)c2c1=O)c1ccccc1 -US08492378B2,1,CS(=O)c1ccc(-c2coc3ccc(-c4nnc(S)o4)cc23)cc1.Clc1cccc(CBr)c1>>CS(=O)c1ccc(-c2coc3ccc(-c4nnc(SCc5cccc(Cl)c5)o4)cc23)cc1 -US20090030012A1,7,CC(C)(C)OC(=O)N1CC=C(c2nccc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)CC1>>CC(C)(C)OC(=O)N1CCC(c2nccc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)CC1 -US05019577,1,CC(=O)Nc1nc(N(C(C)=O)C(C)=O)c(CCC=O)c(=O)[nH]1.CCOC(=O)CC[C@H](NC(=O)c1ccc(N)c(F)c1)C(=O)OCC>>CCOC(=O)CC[C@H](NC(=O)c1ccc(NCCCc2c(N(C(C)=O)C(C)=O)nc(NC(C)=O)[nH]c2=O)c(F)c1)C(=O)OCC -US20130005716A1,2,CN(C)C(=O)c1cccc(S(=O)(=O)Cl)c1.O=C(O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1)[C@H]1NCCS1>>CN(C)C(=O)c1cccc(S(=O)(=O)N2CCS[C@H]2C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)c1 -US20130190268A1,6,COC(=O)CCCCCOCCCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>O=C(O)CCCCCOCCCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 -US20100098634A1,6,COc1ccc2nc(N)sc2c1>>Nc1nc2ccc(O)cc2s1 -US20060235035A1,2,CCN(CC)CCNC(=O)c1ccc(N)cc1OC.O=C=Nc1cccc(Cl)c1>>CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1OC -US04841062,2,CC(C)ON=C(C(=O)O)c1csc(N)n1.O=CO>>CC(C)ON=C(C(=O)O)c1csc(NC=O)n1 -US20110015157A1,2,C[C@@H](c1ccc(-c2ccc(F)cc2F)cc1)N1CC[C@](CCN)(c2ccc(F)cc2)OC1=O.O=C(O)CO>>C[C@@H](c1ccc(-c2ccc(F)cc2F)cc1)N1CC[C@](CCNC(=O)CO)(c2ccc(F)cc2)OC1=O -US06339160B1,6,CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)O1)C(=O)OC(C)(C)C>>CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)O1)C(=O)O -US20100240642A1,1,COCCBr.OCc1cc(O)cc(OCC2CC2)c1>>COCCOc1cc(CO)cc(OCC2CC2)c1 -US20150239900A1,6,C=CC(=O)N1CCN(c2ncnc3cc(-c4ccccc4F)c(OC)cc23)CC1>>C=CC(=O)N1CCN(c2ncnc3cc(-c4ccccc4F)c(O)cc23)CC1 -US07786145B2,1,CC=O.Nc1ccc2nc(S)sc2c1>>CCNc1ccc2nc(S)sc2c1 -US07622592B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(N)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)Nc1ccc(N)c([N+](=O)[O-])c1 -US08313669B2,3,Brc1cc(Br)cc(Br)c1.OB(O)c1ccc(OCc2ccccc2)cc1>>Brc1cc(Br)cc(-c2ccc(OCc3ccccc3)cc2)c1 -US08101632B2,1,Cc1cc(F)ccc1[N+](=O)[O-].O=c1[nH]ccc2oc(-c3cccc(Cl)c3)cc12>>Cc1cc(-n2ccc3oc(-c4cccc(Cl)c4)cc3c2=O)ccc1[N+](=O)[O-] -US20090088430A1,6,CC(C)(C)OC(=O)N1CCC(N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(F)cc4)cc3Cl)C2=O)CC1>>O=C1[C@H](Cc2c(Cl)cc(-c3ccc(F)cc3)cc2Cl)CCN1C1CCNCC1 -US07678787B2,1,CNC.O=Cc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1>>CN(C)Cc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1 -US20070082912A1,6,COC(=O)c1cc(N2CCCC2=O)cc(-n2c(C)ccc2-c2cc(C)ccc2OCc2ccc(F)cc2)c1>>Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2cc(C(=O)O)cc(N3CCCC3=O)c2)c1 -US20090118284A1,7,COC(=O)c1cc(I)ccn1>>OCc1cc(I)ccn1 -US05620987,6,CC(C)(C)OC(=O)N[C@H]1CN(C(C)(C)C)[C@](C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)(C(N)=O)C1>>CC(C)(C)OC(=O)N[C@H]1CN(C(C)(C)C)[C@](C[C@@H](O)[C@@H](N)Cc2ccccc2)(C(N)=O)C1 -US08921576B2,6,CC(=O)N1CCC2(C1)CN(C(=O)Nc1ncc(SCCCN3C(=O)c4ccccc4C3=O)s1)c1ccc(Cl)cc12>>CC(=O)N1CCC2(C1)CN(C(=O)Nc1ncc(SCCCN)s1)c1ccc(Cl)cc12 -US05160661,3,Clc1ccc(COC2CCCCO2)cn1.Fc1ccc(Br)cc1>>Fc1ccc(-c2ccc(COC3CCCCO3)cn2)cc1 -US06441004B1,2,NS(=O)(=O)c1ccccc1.O=C(O)c1cc2ccccc2n1Cc1ccc(Cl)c(Cl)c1>>O=C(NS(=O)(=O)c1ccccc1)c1cc2ccccc2n1Cc1ccc(Cl)c(Cl)c1 -US05756502,9,CC(C)Oc1cccc(N)c1.S=C(Cl)Cl>>CC(C)Oc1cccc(N=C=S)c1 -US20130059849A1,6,CCOC(=O)c1cc(C(C)(C)C)nc2c1c(C)nn2C(C)(C)C>>Cc1nn(C(C)(C)C)c2nc(C(C)(C)C)cc(C(=O)O)c12 -US06355680B1,1,Cc1ccc(N)cc1.O=C(O)Cc1ccccc1Br>>Cc1ccc(Nc2ccccc2CC(=O)O)cc1 -US08748426B2,6,COC(=O)[C@H](C(C)C)N1Cc2cc(-c3ccc(NC(=S)Nc4ccc(Cl)cc4)cc3)ccc2C1=O>>CC(C)[C@@H](C(=O)O)N1Cc2cc(-c3ccc(NC(=S)Nc4ccc(Cl)cc4)cc3)ccc2C1=O -US20070259965A1,6,CC(CCNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>CC(N)CCNC(=O)OC(C)(C)C -US20100249094A1,3,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(OS(=O)(=O)C(F)(F)F)cc12.COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(C)cc1OC>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)OC)c(OC)cc3C)cc12 -US08513239B2,1,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC2(CCNCC2)CC1.NC(=O)CCl>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCC2(CCN(CC(N)=O)CC2)CC1 -US20140296225A1,1,N#Cc1ccc2c(c1)CCC(N1CCNCC1=O)C2.O=CCc1ccc2c(=O)occc2c1>>N#Cc1ccc2c(c1)CCC(N1CCN(CCc3ccc4c(=O)occc4c3)CC1=O)C2 -US08222248B2,1,Cc1cc(O)cc(C)c1C=O.O=C(CCl)N1CCCC1>>Cc1cc(OCC(=O)N2CCCC2)cc(C)c1C=O -US20030013721A1,2,C[C@H]1CN(CC(=O)Nc2cccc3ncccc23)CCN1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>C[C@H]1CN(CC(=O)Nc2cccc3ncccc23)CCN1S(=O)(=O)c1ccc(C#N)cc1 -US07956083B2,1,C=Cc1cc(OC)c2cc[nH]c2c1.COc1ccc(B(O)O)cc1F>>C=Cc1cc(OC)c2ccn(-c3ccc(OC)c(F)c3)c2c1 -US07179835B2,1,CC(C)(C)OC(=O)NCC=O.NCC1CC1>>CC(C)(C)OC(=O)NCCNCC1CC1 -US20040138211A1,3,COC(=O)CC(=O)OC.O=Cc1ccc(OCCOc2ccc3ncccc3c2)cc1>>COC(=O)C(=Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)OC -US20120316366A1,1,CC(C)=CCC/C(C)=C/CCl.CCOP(OCC)OCC>>CCOP(=O)(C/C=C(\C)CCC=C(C)C)OCC -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCCNCC3)nn12.O=Cc1ccccc1F>>Fc1ccccc1CN1CCCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1 -US20100105682A1,1,CC(C)(C)N.O=C[C@@H]1C[C@H]1C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>CC(C)(C)NC[C@@H]1C[C@H]1C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1 -US04316893,1,CCCCCBr.O=C1CCCCCN1>>CCCCCN1CCCCCC1=O -US20100029634A1,1,CN(Cc1cn(-c2ccccc2CN)nn1)C1CCCc2cccnc21.O=Cc1ccccn1>>CN(Cc1cn(-c2ccccc2CNCc2ccccn2)nn1)C1CCCc2cccnc21 -US20100004222A1,2,Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)O.Nc1ccc2cc(C(O)CO)cnc2c1>>Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)Nc1ccc2cc(C(O)CO)cnc2c1 -US20120068123A1,3,N#Cc1cccc(Cl)c1C#N.OB(O)c1c2ccccc2cc2ccccc12>>N#Cc1cccc(-c2c3ccccc3cc3ccccc23)c1C#N -US20120172392A1,6,O=C1c2ccccc2C(=O)N1CC=C(Cc1ccccc1)C(F)(F)F>>NCC=C(Cc1ccccc1)C(F)(F)F -US20140171405A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C1c2ccc(Br)cc2CN1CC(F)(F)F>>CC1(C)OB(c2ccc3c(c2)CN(CC(F)(F)F)C3=O)OC1(C)C -US20080269255A1,7,COCCCCc1cccc(C=O)c1>>COCCCCc1cccc(CO)c1 -US06274588B1,1,CI.Cc1ncc(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(-c2ccccc2)n1>>Cc1ncc(C(=O)N(C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(-c2ccccc2)n1 -US05521179,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCc1c[nH]cn1>>CC(C)(C)OC(=O)n1cnc(CO)c1 -US05496805,2,CC(=O)SCC(Cc1ccccc1)C(=O)Cl.COC(=O)[C@H](C)N>>COC(=O)[C@H](C)NC(=O)C(CSC(C)=O)Cc1ccccc1 -US20130059834A1,2,CS(=O)(=O)Cl.C[C@H](CO)NC(=O)OC(C)(C)C>>C[C@H](COS(C)(=O)=O)NC(=O)OC(C)(C)C -US20100062050A1,6,Cc1ccc(S(=O)(=O)NC(=N)NCCCCCCOC(=O)CCC(NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1>>Cc1ccc(S(=O)(=O)NC(=N)NCCCCCCOC(=O)CCC(NC(=O)OC(C)(C)C)C(=O)O)cc1 -US20100081670A1,1,Cc1nc(CO)co1.O=S(=O)(Nc1ncc(Cl)nc1Cl)c1cccc(Cl)c1Cl>>Cc1nc(COc2nc(Cl)cnc2NS(=O)(=O)c2cccc(Cl)c2Cl)co1 -US08314132B2,1,COc1ccc(CC(=O)c2cc(Cl)c(O)cc2O)cc1.NN>>COc1ccc(CC(=NN)c2cc(Cl)c(O)cc2O)cc1 -US20090227560A1,6,COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCN(Cc3ccccc3)C[C@H]2CCOc2ccccc2)c1-c1ccccc1>>COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCNC[C@H]2CCOc2ccccc2)c1-c1ccccc1 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2ccnnc2)c1.Cc1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl>>Cc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnnc3)c2)cc1Cl -US20130338358A1,1,COc1cc(F)ccc1[N+](=O)[O-].O=C1CCNCC1>>COc1cc(N2CCC(=O)CC2)ccc1[N+](=O)[O-] -US08969345B2,1,C/C(C#N)=C1/c2ccc(CBr)cc2COc2cc(F)ccc21.COCc1nc2c(Cl)cccc2[nH]1>>COCc1nc2c(Cl)cccc2n1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)C#N -US05102667,2,CC(C(=O)O)c1ccccc1N(C)C.O=C1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12>>CC(C(=O)N1C[C@@H]2C(=O)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1)c1ccccc1N(C)C -US07576104B2,1,CCCCC=O.Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O>>CCCCCNc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O -US04389329,3,CCCO[C@@H]1CC[C@@H](C=O)CC1.COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCO[C@@H]1CC[C@@H](C=COC)CC1 -US20030220366A1,1,CC(=O)Oc1cccc(O)c1.OC1CCC1>>CC(=O)Oc1cccc(OC2CCC2)c1 -US20150152058A1,2,CS(=O)(=O)c1cc(C(=O)O)cc(C(F)(F)F)c1.Fc1ccccc1-c1ccncc1NCC(F)F>>CS(=O)(=O)c1cc(C(=O)N(CC(F)F)c2cnccc2-c2ccccc2F)cc(C(F)(F)F)c1 -US06514996B2,8,COc1ccc(C(O)Cc2c(Cl)cncc2Cl)c2c1OCCO2>>COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)c2c1OCCO2 -US08404859B2,10,COC(=O)c1sc(C)cc1C#N.O=C1CCC(=O)N1Br>>COC(=O)c1sc(CBr)cc1C#N -US07781443B2,6,CCOC(=O)C1CCN(c2cnc(N[C@H]3C[C@@H](CC)N(C(=O)OC(C)(C)C)c4ccc(OC)nc43)nc2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1>>CC[C@@H]1C[C@H](Nc2ncc(N3CCC(C(=O)O)CC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OC(C)(C)C -US20090286778A1,7,O=C(NCc1cccc(Nc2nc(Cl)ncc2Cl)c1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(C(=O)NCc2cccc(Nc3nc(Cl)ncc3Cl)c2)c1 -US07279470B2,2,CN(C(=O)Cl)c1ccccc1.O=C(c1ccccc1)c1ccc(O)cc1>>CN(C(=O)Oc1ccc(C(=O)c2ccccc2)cc1)c1ccccc1 -US20100216813A1,2,CCCS(=O)(=O)Cl.N#Cc1ccc(N(Cc2cc(Cl)ccc2Cl)[C@H]2CCNC2)cc1Cl>>CCCS(=O)(=O)N1CC[C@H](N(Cc2cc(Cl)ccc2Cl)c2ccc(C#N)c(Cl)c2)C1 -US20060074243A1,3,CC(C)(C)OC(=O)C1(S(=O)(=O)c2ccc(-c3ccc(Br)cc3)cc2)CCOCC1.FC(F)(F)C(F)(F)CCI>>CC(C)(C)OC(=O)C1(S(=O)(=O)c2ccc(-c3ccc(CCC(F)(F)C(F)(F)F)cc3)cc2)CCOCC1 -US05525742,6,CC(C)(C)OC(=O)Nc1cc(Cl)cc(N=[N+]=[N-])c1>>[N-]=[N+]=Nc1cc(N)cc(Cl)c1 -US08828987B2,2,COC(=O)c1ccc(C2(N)CC2)cc1.O=C(O)c1cc(Cl)cnc1N1CC(Oc2ccccc2)C1>>COC(=O)c1ccc(C2(NC(=O)c3cc(Cl)cnc3N3CC(Oc4ccccc4)C3)CC2)cc1 -US20060079555A1,2,CC(C)(C)OC(=O)N1CCC(=C(Br)c2ccc(C(=O)O)cc2)CC1.CCNCC>>CCN(CC)C(=O)c1ccc(C(Br)=C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US06184238B2,1,CI.c1cncc(-c2cc3ccccc3[nH]2)c1>>Cn1c(-c2cccnc2)cc2ccccc21 -US20150182509A1,2,C1CCNC1.CCOC(=O)CC1C=C2C=C(Cl)N=CC23NC(C)CC3C1>>CC1CC2CC(CC(=O)N3CCCC3)C=C3C=C(Cl)N=CC32N1 -US06617336B1,3,CCN(CC)C(CO)c1cccc2ccc(OS(=O)(=O)C(F)(F)F)nc12.OB(O)c1ccccc1>>CCN(CC)C(CO)c1cccc2ccc(-c3ccccc3)nc12 -US20140187588A1,3,CCCO[C@H]1CCC[C@H](N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)O[C@@H](C)[C@@H]1Oc1ccc(Br)cc1.OB(O)c1ccccc1>>CCCO[C@H]1CCC[C@H](N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)O[C@@H](C)[C@@H]1Oc1ccc(-c2ccccc2)cc1 -US05648373,1,CCOC(=O)CCCCCCCBr.Cc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>CCOC(=O)CCCCCCCn1c(C)nc(-c2ccccc2)c1-c1ccccc1 -US20100261683A1,1,CO[C@@](C(=O)O)(c1ccccc1)C(F)(F)F.Oc1c(F)c(F)c(F)c(F)c1F>>CO[C@@](C(=O)Oc1c(F)c(F)c(F)c(F)c1F)(c1ccccc1)C(F)(F)F -US08101624B2,6,COC(=O)c1ccc2c(=O)[nH]c(Cc3ccc(Cl)c(Cl)c3)nc2c1>>O=C(O)c1ccc2c(=O)[nH]c(Cc3ccc(Cl)c(Cl)c3)nc2c1 -US20150266819A1,2,COc1cc(OC)c(CCN)c(OC)c1.COc1ccc(C(=O)O)cc1[N+](=O)[O-]>>COc1cc(OC)c(CCNC(=O)c2ccc(OC)c([N+](=O)[O-])c2)c(OC)c1 -US05202437,2,O=C(Cl)OCc1ccc([N+](=O)[O-])cc1.O=C(OCc1ccc([N+](=O)[O-])cc1)N1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1CN1CCNCC1>>O=C(OCc1ccc([N+](=O)[O-])cc1)N1CCN(C[C@@H]2C[C@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)CC1 -US20120053053A1,3,C=CB1OC(C)(C)C(C)(C)O1.COC(=O)COc1nc(SC)nc(N)c1I>>C=Cc1c(N)nc(SC)nc1OCC(=O)OC -US20090143354A1,3,N#CCCCC[Zn]Br.O=C(NCC1CCCCC1)c1c(Cl)ccc2nc(Cl)ccc12>>N#CCCCCc1ccc2c(C(=O)NCC3CCCCC3)c(Cl)ccc2n1 -US05250548,2,CO.O=C(O)c1cccnc1O>>COC(=O)c1cccnc1O -US04273704,6,COC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C>>C[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)O -US04064259,2,C=CCCCCN.CCSc1ncc(C(=O)O)s1>>C=CCCCCNC(=O)c1cnc(SCC)s1 -US20070191389A1,2,CC(C)OC(=O)Cl.Fc1ccccc1-n1cc(C2=CCNCC2)nn1>>CC(C)OC(=O)N1CC=C(c2cn(-c3ccccc3F)nn2)CC1 -US05252605,2,O=C(CCCCCO)OCc1ccccc1.O=C(Cl)c1ccccc1>>O=C(CCCCCOC(=O)c1ccccc1)OCc1ccccc1 -US20040058903A1,2,Cc1ccc(-c2ccccc2C(=O)O)cc1.Nc1ccc(O)cc1>>Cc1ccc(-c2ccccc2C(=O)Nc2ccc(O)cc2)cc1 -US20150232444A1,1,C#CCBr.O=S(=O)(c1ccccc1)N1CCC(N2CCCCC2CCO)CC1>>C#CCOCCC1CCCCN1C1CCN(S(=O)(=O)c2ccccc2)CC1 -US08975254B2,2,C[C@H](N)Cn1cc(C#N)c(-c2ccc(C#N)c(Cl)c2)n1.Cn1cnc(C(=O)O)c1>>C[C@@H](Cn1cc(C#N)c(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cn(C)cn1 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2ccnc(N3CCOCC3)c2)c1.Cc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F>>Cc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnc(N4CCOCC4)c3)c2)cc1C(F)(F)F -US20120058997A1,3,Clc1ccc2ncc(Br)n2n1.OB(O)c1cccc(OC(F)(F)F)c1>>FC(F)(F)Oc1cccc(-c2cnc3ccc(Cl)nn23)c1 -US04377695,6,COC(=O)CCCCCCCn1c(=O)oc2cc(C)ccc21>>Cc1ccc2c(c1)oc(=O)n2CCCCCCCC(=O)O -US20120214803A1,8,COc1ccc(C(O)c2ccc3cccnc3c2[N+](=O)[O-])c(OC)c1>>COc1ccc(C(=O)c2ccc3cccnc3c2[N+](=O)[O-])c(OC)c1 -US04954339,1,CC(C)=CCC/C(C)=C/CBr.CNC>>CC(C)=CCCC(C)=CCN(C)C -US20150005232A1,1,COC(=O)CBr.O=c1ccc(Br)c[nH]1>>COC(=O)Cn1cc(Br)ccc1=O -US20150166480A1,6,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)F)CC3)cn2)cc1F>>CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)N4C[C@H](O)C[C@H]4C(=O)O)c(F)c3)nc2)CC1 -US20100330130A1,2,CN1CCN(Cc2ccc(C(=O)O)cc2)CC1.Cc1ccc(N)cc1Nc1nccc(-c2cccnc2)n1>>Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1 -US20130252986A1,1,CCBr.O=c1cc(OCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)cc[nH]1>>CCn1ccc(OCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)cc1=O -US06953857B2,1,COC(=O)c1ccc(Cl)c(O)c1.OCCc1ccc(Cl)cc1>>COC(=O)c1ccc(Cl)c(OCCc2ccc(Cl)cc2)c1 -US04563476,1,CC(=O)c1ccc(N)cc1.O=Cc1c(O)ccc2c1CCCO2>>CC(=O)c1ccc(NCc2c(O)ccc3c2CCCO3)cc1 -US06723722B1,6,COC(=O)CC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC(=O)N1NC(=O)OC(C)(C)C>>COC(=O)CC1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC(=O)N1N -US06376491B1,2,CCN.Cc1c(C(=O)O)oc2cccc(OCC(O)CNC(C)C)c12>>CCNC(=O)c1oc2cccc(OCC(O)CNC(C)C)c2c1C -US04503055,2,O=C(CCl)OC(=O)CCl.Oc1ccc(N2CCNCC2)cc1>>O=C(CCl)N1CCN(c2ccc(O)cc2)CC1 -US05017211,2,CC(C)NC(=O)c1cc(N)c(F)cc1Cl.CCOC(=O)Cl>>CCOC(=O)Nc1cc(C(=O)NC(C)C)c(Cl)cc1F -US20150164876A1,7,O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(-c2cc(N3CCOCC3)ccc2[N+](=O)[O-])c1>>Nc1ccc(N2CCOCC2)cc1-c1cc(C(=O)NCc2cccc(C(F)(F)F)c2)ccn1 -US08846012B2,1,C1CCNCC1.COc1ccc(C(Cl)(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1>>COc1ccc(C(c2ccc(OC)cc2)(c2ccc(OC)cc2)N2CCCCC2)cc1 -US07846960B2,6,COC(=O)c1ccc(CN(C)c2c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc2F)cc1C>>COC(=O)c1ccc(CN(C)c2c(C)cc(O)cc2F)cc1C -US20070155805A1,7,CCCCC(=CC(=O)OCC)c1sc2cc(F)ccc2c1C>>CCCCC(CC(=O)OCC)c1sc2cc(F)ccc2c1C -US20050137171A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COP(=O)(Oc1ccc2[nH]nc(I)c2c1)c1ccccc1>>COP(=O)(Oc1ccc2c(c1)c(I)nn2C(=O)OC(C)(C)C)c1ccccc1 -US20140303161A1,2,N#CCC(=O)O.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCCNC1>>N#CCC(=O)N1CCCC(n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1 -US20150087639A1,1,C1COCCN1.O=[N+]([O-])c1cc(F)c(F)c(F)c1>>O=[N+]([O-])c1cc(F)c(N2CCOCC2)c(F)c1 -US06137007,2,CC(=O)OC(C)=O.N[C@H]1C=C[C@@H](CO)C1>>CC(=O)N[C@H]1C=C[C@@H](CO)C1 -US20100292279A1,3,CC(C)OB(C#CC(C)(C)C)OC(C)C.NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)c(OCC2CC2)c1>>CC(C)(C)C#Cc1ccc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cc1OCC1CC1 -US20090304692A1,1,NCc1ccccc1.O=C1CCN(c2nc(-c3ccc(NC(=O)Nc4ccncc4)cc3)nc(N3CC4CCC(C3)O4)n2)CC1>>O=C(Nc1ccncc1)Nc1ccc(-c2nc(N3CCC(NCc4ccccc4)CC3)nc(N3CC4CCC(C3)O4)n2)cc1 -US20090156572A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CN(C(=O)c1ccc(N2CCOCC2)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1>>CN(C(=O)c1ccc(N2CCOCC2)cc1)[C@@H]1CCN(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US20090312381A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)CNc1ccccc1C(F)(F)F>>CC(C)(C)OC(=O)N(CC(=O)O)c1ccccc1C(F)(F)F -US20070167488A1,2,Cc1cc(C(=O)O)[nH]c1C=C1C(=O)Nc2ccccc21.NCCCCc1ccccc1>>Cc1cc(C(=O)NCCCCc2ccccc2)[nH]c1C=C1C(=O)Nc2ccccc21 -US20030149266A1,1,Cc1cnc(Cl)nc1Nc1ccccc1.Nc1ccc(C(=O)NCCCn2ccnc2)cc1>>Cc1cnc(Nc2ccc(C(=O)NCCCn3ccnc3)cc2)nc1Nc1ccccc1 -US20100029617A1,2,CCn1nc(C)cc1CCCN.Cc1ccc(CCC(=O)O)cc1C>>CCn1nc(C)cc1CCCNC(=O)CCc1ccc(C)c(C)c1 -US08546359B2,1,CC(C)(C)C1CCC(Oc2ccc3cc([C@]4(C)COC(=O)N4)ccc3c2)CC1.CI>>CN1C(=O)OC[C@@]1(C)c1ccc2cc(OC3CCC(C(C)(C)C)CC3)ccc2c1 -US20120101124A1,6,CCOC(=O)CCc1ccc(-c2noc(-c3cnc(OC(C)C)c(Cl)c3)n2)c2ccn(CC)c12>>CCn1ccc2c(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)ccc(CCC(=O)O)c21 -US05763458,2,CC(=O)OC(C)=O.CC(=O)c1ccc(N)c2c1OCCO2>>CC(=O)Nc1ccc(C(C)=O)c2c1OCCO2 -US04454148,6,COc1ccc2sc(S(N)(=O)=O)nc2c1>>NS(=O)(=O)c1nc2cc(O)ccc2s1 -US06924292B2,8,N#Cc1cccc(C(=O)Nc2c(Cl)cncc2Cl)c1.O=C(OO)c1cccc(Cl)c1>>N#Cc1cccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c1 -US04672066,2,CCCc1c(OCCCCCC(=O)O)ccc(C(C)=O)c1O.NCCCCc1ccccn1>>CCCc1c(OCCCCCC(=O)NCCCCc2ccccn2)ccc(C(C)=O)c1O -US05208251,6,CCOC(=O)c1cc(C=Cc2ccc(O)c(OC)c2)n[nH]1>>COc1cc(C=Cc2cc(C(=O)O)[nH]n2)ccc1O -US20100317842A1,9,BrC(Br)(Br)Br.OCc1cccc(OCCF)c1>>FCCOc1cccc(CBr)c1 -US08829035B2,7,CC(C)Nc1ccc(-c2nc3ccccc3o2)cc1[N+](=O)[O-]>>CC(C)Nc1ccc(-c2nc3ccccc3o2)cc1N -US20070060633A1,3,O=C(c1ccccc1)c1ccc2c(c1)nnn2-c1ccc(F)cc1.[Mg+]C1CC1>>OC(c1ccccc1)(c1ccc2c(c1)nnn2-c1ccc(F)cc1)C1CC1 -US05840726,1,C=CCBr.CC(C)(C)OC(=O)NCC(c1ccccc1)c1ccccc1>>C=CCN(CC(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C -US06045776,2,CC(Br)C(=O)O.NCCC(=O)O>>CC(Br)C(=O)NCCC(=O)O -US06265575B1,9,NCc1ccc2c(C(O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(OCCN4CCCC4)cc3)sc2c1>>NCc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(OCCN4CCCC4)cc3)sc2c1 -US20060160832A1,1,CCN(CC)CCCO.COc1cc2c(Sc3ccc([N+](=O)[O-])s3)ccnc2cc1O>>CCN(CC)CCCOc1cc2nccc(Sc3ccc([N+](=O)[O-])s3)c2cc1OC -US08318757B2,2,CCSCC(=O)O.CNCc1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1Cl>>CCSCC(=O)N(C)Cc1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1Cl -US20060160794A1,2,CNCc1ccccc1Cl.O=C(O)c1cn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)nn1>>CN(Cc1ccccc1Cl)C(=O)c1cn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)nn1 -US20090186886A1,1,CN(C)CCN.[O-][n+]1nc(Cl)nc2cc3c(cc21)OCCC3>>CN(C)CCNc1nc2cc3c(cc2[n+]([O-])n1)OCCC3 -US20120190695A1,2,CC(C)(O)c1nc(-c2cccc(CN)c2)no1.O=C(O)c1cnc(-c2ccccn2)nc1>>CC(C)(O)c1nc(-c2cccc(CNC(=O)c3cnc(-c4ccccn4)nc3)c2)no1 -US20040242890A1,2,CS(=O)(=O)Cl.O=C1CNC(=O)N1c1cccc(I)c1>>CS(=O)(=O)N1CC(=O)N(c2cccc(I)c2)C1=O -US20130045962A1,2,CNC1(C(=O)OC)CC1.O=C(O)CNC(=O)OCc1ccccc1>>COC(=O)C1(N(C)C(=O)CNC(=O)OCc2ccccc2)CC1 -US20050065143A1,2,CC(=O)Oc1ccccc1C(=O)Cl.O=C(NCCC1CC1)c1ccc(N2CCNCC2)nn1>>CC(=O)Oc1ccccc1C(=O)N1CCN(c2ccc(C(=O)NCCC3CC3)nn2)CC1 -US05100891,2,CN1C2C=CC(O)=CC2C2CCC(N)C21.O=C(Cl)OCc1ccccc1>>CN1C2C=CC(O)=CC2C2CCC(NC(=O)OCc3ccccc3)C21 -US20050107449A1,3,CC(=O)c1oc(-c2ccc(C(F)(F)F)cc2)nc1C.C[Mg+]>>Cc1nc(-c2ccc(C(F)(F)F)cc2)oc1C(C)(C)O -US20110160202A1,7,CON(C)C(=O)c1ccc(Oc2nccnc2C2=CCSCC2)cc1>>CON(C)C(=O)c1ccc(Oc2nccnc2C2CCSCC2)cc1 -US20070197512A1,2,CC(C)c1cccc2c1OC(C(C)C)CN2.COC(=O)CCC(=O)Cl>>COC(=O)CCC(=O)N1CC(C(C)C)Oc2c(C(C)C)cccc21 -US20040214721A1,3,C=CC=C.COc1cc(C=C[N+](=O)[O-])ccc1O>>COc1cc([C@@H]2CC=CC[C@H]2[N+](=O)[O-])ccc1O -US07030141B2,2,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@@H]1C(=O)O.CN(C)C(=O)c1ccc(N)c(F)c1>>CN(C)C(=O)c1ccc(NC(=O)[C@H]2C[C@@H](O[Si](C)(C)C(C)(C)C)CN2C(=O)OC(C)(C)C)c(F)c1 -US20130324532A1,9,COC(=O)Cc1ccccc1CCc1nc(Nc2ccc(N3CCC(NC(=O)OC(C)(C)C)CC3)cc2)ncc1C(F)(F)F.[NH4+]>>CC(C)(C)OC(=O)NC1CCN(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4CC(N)=O)n3)cc2)CC1 -US07906532B2,2,C1COCCN1.CC(C)n1nc(C(=O)N[C@H]2C[C@@H](CC(=O)O)N(C(=O)OC(C)(C)C)C2)c2ccccc21>>CC(C)n1nc(C(=O)N[C@H]2C[C@@H](CC(=O)N3CCOCC3)N(C(=O)OC(C)(C)C)C2)c2ccccc21 -US20010044445A1,4,NNc1ccc([N+](=O)[O-])cc1.O=C(CC(=O)C(F)(F)F)c1ccco1>>O=[N+]([O-])c1ccc(-n2nc(C(F)(F)F)cc2-c2ccco2)cc1 -US20120238539A1,6,CC(C)(C)OC(=O)N1CCN(c2nc(N)c([N+](=O)[O-])cc2Cl)CC1>>Nc1nc(N2CCNCC2)c(Cl)cc1[N+](=O)[O-] -US20140228417A1,4,CCOC(=O)C(Br)C(C)=O.NC(=S)c1ccc(O)cc1>>CCOC(=O)c1sc(-c2ccc(O)cc2)nc1C -US08188098B2,1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.CCOc1ccc(O)c(F)c1>>CCOc1ccc(Oc2ncnc3c2cnn3C2CCN(C(=O)OC(C)(C)C)CC2)c(F)c1 -US20110053931A1,6,O=c1[nH]cncc1-c1ccc(OCc2ccccc2)c(F)c1>>O=c1[nH]cncc1-c1ccc(O)c(F)c1 -US07579466B2,1,C#CCCl.CCN(CC)c1ncc(NS(C)(=O)=O)c(N[C@@H](Cc2ccc(OC(=O)N3CCCC3)cc2)C(=O)OC(C)(C)C)n1>>C#CCN(c1cnc(N(CC)CC)nc1N[C@@H](Cc1ccc(OC(=O)N2CCCC2)cc1)C(=O)OC(C)(C)C)S(C)(=O)=O -US05773612,3,O=C1Nc2ccc(Cl)cc2C1=O.[Mg+]Cc1ccccc1>>O=C1Nc2ccc(Cl)cc2C1(O)Cc1ccccc1 -US04659734,1,CCOC(=O)c1c(S)nc2cc(Cl)c(F)cc2c1O.O=C1CCCCC1Cl>>CCOC(=O)c1c(SC2CCCCC2=O)nc2cc(Cl)c(F)cc2c1O -US20100210642A1,3,C#Cc1cnc2c(C)cc(-c3ccc(Cl)cc3)cn12.NS(=O)(=O)c1cncc(Br)c1>>Cc1cc(-c2ccc(Cl)cc2)cn2c(C#Cc3cncc(S(N)(=O)=O)c3)cnc12 -US06403804B1,2,CCOC(=O)C[C@@H](O)CNC(C)=O.NN>>CC(=O)NC[C@H](O)CC(=O)NN -US06277885B1,3,COC(=O)c1cc(Br)cc(C)c1N.OB(O)c1ccccc1>>COC(=O)c1cc(-c2ccccc2)cc(C)c1N -US20040034089A1,6,CCCc1nc(C2Cc3ccccc3N2C(C)=O)no1>>CCCc1nc(C2Cc3ccccc3N2)no1 -US07132425B2,1,CNC.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2cnc(CBr)cn2)cc1Cl>>CN(C)Cc1cnc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)cn1 -US06211199B1,1,COc1cc(C(=O)N2CCC(CCOS(C)(=O)=O)(c3ccccc3)C2)cc(OC)c1OC.c1ccc2[nH]c(NC3CCNCC3)nc2c1>>COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5[nH]4)CC3)(c3ccccc3)C2)cc(OC)c1OC -US20070191429A1,2,CCOC(=O)c1cc([C@H]2CCCNC2)ccc1C.Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)O>>CCOC(=O)c1cc([C@H]2CCCN(C(=O)c3sc(-c4ccc(C(F)(F)F)cc4)nc3C)C2)ccc1C -US20130210803A1,4,CN1CCC(=O)CC1.Cc1ccc(NN)c(Br)c1>>Cc1cc(Br)c2[nH]c3c(c2c1)CN(C)CC3 -US20090270360A1,6,C=C1C[C@H](C(=O)OCC)[C@@H](C(=O)OCC)C1>>C=C1C[C@H](C(=O)OCC)[C@@H](C(=O)O)C1 -US20030212055A1,1,COc1cc2c(Cl)cnnc2cc1O.OCCCN1CCCC1>>COc1cc2c(Cl)cnnc2cc1OCCCN1CCCC1 -US06451805B1,9,Clc1ncnc2c1c(-c1ccco1)nn2Cc1ccccc1>>c1ccc(Cn2nc(-c3ccco3)c3cncnc32)cc1 -US20150152047A1,1,CC(C)(C)OC(=O)NC[C@@H]1CCCN1.CCOC(=O)c1ccc(C=O)c(C(F)(F)F)c1>>CCOC(=O)c1ccc(CN2CCC[C@H]2CNC(=O)OC(C)(C)C)c(C(F)(F)F)c1 -US07273878B2,1,CC(CCCCOS(C)(=O)=O)=C(F)F.CCc1nn(C)c(C(=O)O)c1Cl>>CCc1nn(C)c(C(=O)OCCCCC(C)=C(F)F)c1Cl -US20110092557A1,1,CC[C@H](C)[C@H](N)C(=O)O.O=[N+]([O-])c1cc([N+](=O)[O-])c(F)cc1F>>CC[C@H](C)[C@H](Nc1cc(F)c([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)O -US20130165464A1,3,CCOC(=O)/C=C/B1OC(C)(C)C(C)(C)O1.CN(C)Cc1ccc(Cl)c(Br)c1>>CCOC(=O)/C=C/c1cc(CN(C)C)ccc1Cl -US05624926,1,COc1cc2ncnc(N3CCC(n4c(=O)[nH]c5ccc([N+](=O)[O-])cc5c4=O)CC3)c2cc1OC.O=C1c2ccccc2C(=O)N1CCCBr>>COc1cc2ncnc(N3CCC(n4c(=O)c5cc([N+](=O)[O-])ccc5n(CCCN5C(=O)c6ccccc6C5=O)c4=O)CC3)c2cc1OC -US08030354B2,3,COc1cccc(B(O)O)c1.O=C(O)CCc1cccc(OCc2ccc(Cl)c(OC(F)(F)F)c2)c1>>COc1cccc(-c2ccc(COc3cccc(CCC(=O)O)c3)cc2OC(F)(F)F)c1 -US20040192728A1,6,CCOC(=O)c1cnc2ccc(F)cc2c1>>O=C(O)c1cnc2ccc(F)cc2c1 -US20100216810A1,2,CC(=O)Cl.N#Cc1c(Oc2ccc(F)c(NC(=O)C(F)(F)F)c2)ccc2nc(N)sc12>>CC(=O)Nc1nc2ccc(Oc3ccc(F)c(NC(=O)C(F)(F)F)c3)c(C#N)c2s1 -US20020156081A1,3,CC1(C)OB(c2ccc(Nc3nc4ccccc4o3)c(F)c2)OC1(C)C.CN1CCN([C@@H]2CC[C@H](n3nc(I)c4c(N)ncnc43)CC2)CC1>>CN1CCN([C@@H]2CC[C@H](n3nc(-c4ccc(Nc5nc6ccccc6o5)c(F)c4)c4c(N)ncnc43)CC2)CC1 -US08309734B2,1,O=C(c1ccncc1Br)N1CCCc2ccccc21.Oc1cc(Cl)ccc1Cl>>O=C(c1ccncc1Oc1cc(Cl)ccc1Cl)N1CCCc2ccccc21 -US20080318963A1,2,CC(=O)c1ccc(N2CCNCC2)cc1.CCOC(=O)Nc1nc2ccc(F)cc2nc1OC>>COc1nc2cc(F)ccc2nc1NC(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 -US05683623,1,CCCCCCCCBr.Oc1cccc(F)c1F>>CCCCCCCCOc1cccc(F)c1F -US05726313,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCC(c1ccc(Cl)c(Cl)c1)N(C)CCO>>CN(CC(c1ccc(Cl)c(Cl)c1)N(C)CCO)C(=O)OC(C)(C)C -US20110135671A1,1,C1CCC(N2CCNCC2)CC1.CCCCOc1nc(N)c2nc(OC)n(CCCCl)c2n1>>CCCCOc1nc(N)c2nc(OC)n(CCCN3CCN(C4CCCCC4)CC3)c2n1 -US05156667,1,CC(/C=C/CO)Oc1ccc(O)cc1.Clc1ccc2nc(Cl)cnc2c1>>CC(C=CCO)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1 -US20110039821A1,1,CC(O)c1ccccn1.Cn1ccc(NC(=O)c2cc(O)c3c(c2)OC(C)(C)C3)n1>>CC(Oc1cc(C(=O)Nc2ccn(C)n2)cc2c1CC(C)(C)O2)c1ccccn1 -US20040058425A1,6,CC(C)c1ccc(COc2ccc(CC(=O)NCCNC(=O)OC(C)(C)C)cc2Cl)cc1>>CC(C)c1ccc(COc2ccc(CC(=O)NCCN)cc2Cl)cc1 -US08410109B2,1,CC(=O)c1cc(CCl)ccc1O.CNC>>CC(=O)c1cc(CN(C)C)ccc1O -US06365751B1,7,O=C1C=COC(COCc2ccccc2)C1>>O=C1CCOC(COCc2ccccc2)C1 -US20050014765A1,2,Nc1nc(-c2ccccc2)c(C(=O)O)s1.OCc1cccc(N2CCNCC2)c1>>Nc1nc(-c2ccccc2)c(C(=O)N2CCN(c3cccc(CO)c3)CC2)s1 -US20130204017A1,2,CCCCCCCC(=O)Cl.O=C1O[C@H]([C@@H](O)CO)C(O)=C1OCC(O)CO>>CCCCCCCC(=O)OC1=C(OCC(O)CO)C(=O)O[C@@H]1[C@@H](O)CO -US20100256356A1,1,C=O.COc1ccc(Cn2nc(C3CCNCC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(C3CCN(C)CC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1 -US20010034352A1,6,COC(=O)N1CCc2c(cccc2S(=O)(=O)N(C)CC2CCN(Cc3ccccc3)CC2)C1>>COC(=O)N1CCc2c(cccc2S(=O)(=O)N(C)CC2CCNCC2)C1 -US20070265298A1,6,COC(=O)c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)c(F)c2)cc1>>O=C(O)c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)c(F)c2)cc1 -US05190969,9,COC(=O)[C@@H]1O[C@@H]1COCc1ccccc1.[NH4+]>>NC(=O)[C@@H]1O[C@@H]1COCc1ccccc1 -US07981882B2,1,CC(C)(C)[Si](C)(C)OC1CNC1.O=C(N1CCc2ccc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F>>CC(C)(C)[Si](C)(C)OC1CN(c2c(Cl)ccc3c2CCN(C(=O)C(F)(F)F)CC3)C1 -US20100210619A1,1,CC(C)CNC1CCCC1.Cc1cc(S(N)(=O)=O)ccc1NC(=O)c1cc(Cl)ncn1>>Cc1cc(S(N)(=O)=O)ccc1NC(=O)c1cc(N(CC(C)C)C2CCCC2)ncn1 -US20100216746A1,2,Cc1nc(Br)c(C(=O)O)[nH]1.N#Cc1cc(Cl)cc(Oc2c(Br)ccc(CN)c2F)c1>>Cc1nc(Br)c(C(=O)NCc2ccc(Br)c(Oc3cc(Cl)cc(C#N)c3)c2F)[nH]1 -US20040006119A1,2,Cc1cscc1N=C=S.Nc1cc(C(F)(F)F)cc(Cl)c1N>>Cc1cscc1NC(=S)Nc1cc(C(F)(F)F)cc(Cl)c1N -US20090124596A1,1,CN(C)CCCN.O=C(O)c1cc(F)cnc1Cl>>CN(C)CCCNc1ncc(F)cc1C(=O)O -US20060173022A1,2,NCCSCc1ccccc1.O=C(Cl)c1cnccc1C(F)(F)F>>O=C(NCCSCc1ccccc1)c1cnccc1C(F)(F)F -US07919502B2,3,CC1(C)OB(c2ccnc(N3CCOCC3)c2Cl)OC1(C)C.Fc1ccc(F)c(CN2CCNc3ncc(I)cc32)c1Cl>>Fc1ccc(F)c(CN2CCNc3ncc(-c4ccnc(N5CCOCC5)c4Cl)cc32)c1Cl -US06734180B1,1,NC1Cc2ccccc2C1.Oc1ncnc2ncccc12>>c1ccc2c(c1)CC(Nc1ncnc3ncccc13)C2 -US20120065404A1,2,CC(C)C[C@H](N)c1ccccc1N1CCCCC1.CCOC(=O)c1ccc(CC(=O)O)cc1OCC>>CCOC(=O)c1ccc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)cc1OCC -US20060183897A1,3,CCOC(=O)c1cccc(Br)c1.OB(O)c1ccccc1OC(F)(F)F>>CCOC(=O)c1cccc(-c2ccccc2OC(F)(F)F)c1 -US20090163471A1,6,NC(=O)c1ccc(C(=O)OCc2ccccc2)cc1NC1CCCCC1>>NC(=O)c1ccc(C(=O)O)cc1NC1CCCCC1 -US20070244113A1,1,CCOc1ccc(N)cc1.Clc1nc(Cl)c2ccccc2n1>>CCOc1ccc(Nc2nc(Cl)nc3ccccc23)cc1 -US06927230B2,1,COc1ccc(C(=O)Cl)cc1.COc1ccc(NNC(N)=O)cc1>>COc1ccc(C(=O)N(NC(N)=O)c2ccc(OC)cc2)cc1 -US06515015B1,7,C=CCc1cc(Oc2ccccc2)ccc1O>>CCCc1cc(Oc2ccccc2)ccc1O -US04914106,9,CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3[C@H](O)[C@@H](Cl)C4=CC(=O)OC(O)[C@]4(C)[C@H]3CC[C@@]21C>>CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3[C@H](O)[C@@H](Cl)C4=CC(=O)OC[C@]4(C)[C@H]3CC[C@@]21C -US20130225552A1,1,CC(C)(C)OC(=O)N[C@@H]1C[C@@H](OS(C)(=O)=O)C1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@@H]1C[C@H](N=[N+]=[N-])C1 -US20140235628A1,3,C#CC1(O)CCN(C(=O)Cc2ccc(-n3cnnn3)cc2)CC1.N#Cc1cccc(Br)c1>>N#Cc1cccc(C#CC2(O)CCN(C(=O)Cc3ccc(-n4cnnn4)cc3)CC2)c1 -US09040538B2,1,CCc1noc(CC)c1CBr.Cc1cc(O)nc(S)n1>>CCc1noc(CC)c1CSc1nc(C)cc(O)n1 -US05840732,3,O=C1COC(=O)N1CCCCSc1cccc2nccn12.O=CCCc1ccccc1>>O=C1OC(=CCCc2ccccc2)C(=O)N1CCCCSc1cccc2nccn12 -US20120238750A1,1,CCOC(=O)CCc1ccc(O)cc1.O=[N+]([O-])c1ccc(F)cc1>>CCOC(=O)CCc1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1 -US05607947,1,C1CCN(C2CCNCC2)CC1.CS(=O)(=O)OCC[C@]1(c2ccc(Cl)c(Cl)c2)CCN(C(=O)Cc2c(F)cccc2Cl)C1>>O=C(Cc1c(F)cccc1Cl)N1CC[C@@](CCN2CCC(N3CCCCC3)CC2)(c2ccc(Cl)c(Cl)c2)C1 -US08673942B2,7,CS(=O)(=O)c1ccc(Oc2ccc([N+](=O)[O-])c(OCc3ccccc3)c2)cn1>>CS(=O)(=O)c1ccc(Oc2ccc(N)c(OCc3ccccc3)c2)cn1 -US04235915,7,O=C(CBr)C1COc2ccccc2O1>>OC(CBr)C1COc2ccccc2O1 -US20120028971A1,1,CC(=O)CCCCC(=O)OC(C)(C)C.[NH4+]>>CC(N)CCCCC(=O)OC(C)(C)C -US06593489B1,7,COC(=O)C1=CC[C@H](NC(=O)OC(C)(C)C)C1>>COC(=O)[C@H]1CC[C@H](NC(=O)OC(C)(C)C)C1 -US04107192,2,O=C(Cl)CCc1ccccc1.O=C(OCC=CCO)c1ccccc1>>O=C(CCc1ccccc1)OCC=CCOC(=O)c1ccccc1 -US08546429B2,2,CS(=O)(=O)c1ccc(Nc2ncnc(OC3CCNCC3)c2[N+](=O)[O-])cc1.Cc1nc(C)c(S(=O)(=O)Cl)s1>>Cc1nc(C)c(S(=O)(=O)N2CCC(Oc3ncnc(Nc4ccc(S(C)(=O)=O)cc4)c3[N+](=O)[O-])CC2)s1 -US20150218172A1,1,COc1cc(C(=O)c2cn(C(C)C)c3ncncc23)cc(Cl)n1.N#Cc1ccc(CC(N)=O)cc1>>COc1cc(C(=O)c2cn(C(C)C)c3ncncc23)cc(NC(=O)Cc2ccc(C#N)cc2)n1 -US20100240656A1,7,Cc1c([N+](=O)[O-])c(C(N)=O)nn1Cc1cc2c(cc1Br)OCO2>>Cc1c(N)c(C(N)=O)nn1Cc1cc2c(cc1Br)OCO2 -US20060199817A1,3,Cc1ccc(C(N)=O)cc1B1OC(C)(C)C(C)(C)O1.O=C1CN(c2nncc3cc(Br)ccc23)CCN1>>Cc1ccc(C(N)=O)cc1-c1ccc2c(N3CCNC(=O)C3)nncc2c1 -US20100075953A1,7,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1 -US08592470B2,5,Cc1noc(NS(=O)(=O)c2ccsc2C=O)c1Cl.SCCCS>>Cc1noc(NS(=O)(=O)c2ccsc2C2SCCCS2)c1Cl -US20150164876A1,6,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)Nc2ccc(OC3CCOCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>O=C(O)CCSCc1cccc(C(=O)Nc2ccc(OC3CCOCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1 -US20110263712A1,2,Nc1ccccc1.O=C(O)CCCCCCC(=O)O>>O=C(O)CCCCCCC(=O)Nc1ccccc1 -US20100249123A1,1,COC(=O)c1ccc(O)c(OC)c1.OCc1ccncc1>>COC(=O)c1ccc(OCc2ccncc2)c(OC)c1 -US20150141400A1,6,CCS(=O)(=O)c1c(CNC(=O)OC(C)(C)C)cc(Cl)cc1OC>>CCS(=O)(=O)c1c(CN)cc(Cl)cc1OC -US20140179667A1,1,CC(C)I.COC(=O)c1cc(O)ncc1Br>>COC(=O)c1cc(OC(C)C)ncc1Br -US05210290,2,CCOC(=O)CN.O=C(O)CS(=O)(=O)Nc1ccc(F)c(C(F)(F)F)c1>>CCOC(=O)CNC(=O)CS(=O)(=O)Nc1ccc(F)c(C(F)(F)F)c1 -US20020193612A1,1,COC(=O)c1cccc(-c2ccc(CO)cc2)c1.O=C1NC(=O)c2ccccc21>>COC(=O)c1cccc(-c2ccc(CN3C(=O)c4ccccc4C3=O)cc2)c1 -US05064833,1,CN(c1ccccc1)c1nc(Cl)nc2c(F)cccc12.Cc1cc(F)ccc1N>>Cc1cc(F)ccc1Nc1nc(N(C)c2ccccc2)c2cccc(F)c2n1 -US07429609B2,6,CCOC(=O)c1ccc2[nH]nc(/C=C/c3ccc(F)cc3)c2c1OCCO>>O=C(O)c1ccc2[nH]nc(/C=C/c3ccc(F)cc3)c2c1OCCO -US08785436B2,7,CCOC(=O)C(F)(F)[C@](C)(N[S@](=O)C(C)(C)C)[C@@H]1C[C@H]1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@@H]1C[C@H]1[C@@](C)(N[S@](=O)C(C)(C)C)C(F)(F)CO -US20030207898A1,2,CC(C)(C)C(=O)Cl.Nc1ccccc1SCc1cc(Cl)cc2c1OCOC2>>CC(C)(C)C(=O)Nc1ccccc1SCc1cc(Cl)cc2c1OCOC2 -US20100272680A1,6,CC1(C)COC(=O)N1C1CCN(C(=O)OCc2ccccc2)CC1>>CC1(C)COC(=O)N1C1CCNCC1 -US08552205B2,6,Cc1noc(C2(NC(=O)OC(C)(C)C)CC2)n1>>Cc1noc(C2(N)CC2)n1 -US20130040930A1,6,COc1ccc(CN2C(=O)N(c3ccc(C(=O)N4CCN(c5ncc(C)cc5C)CC4)c(F)c3)C(C)(C)C2=O)cc1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)NC(=O)C4(C)C)cc3F)CC2)c(C)c1 -US20030060494A1,1,Brc1cccc(Sc2nc[nH]n2)n1.CN(C)C(=O)Cl>>CN(C)C(=O)n1cnc(Sc2cccc(Br)n2)n1 -US20050197370A1,1,FS(F)(F)(F)(F)c1ccc(C=Cc2nc(CCl)co2)cc1.Oc1ccc(OCCCn2ccnn2)cc1>>FS(F)(F)(F)(F)c1ccc(C=Cc2nc(COc3ccc(OCCCn4ccnn4)cc3)co2)cc1 -US04645777,3,C=O.CC(=O)c1ccc(C)s1.CNC>>Cc1ccc(C(=O)CCN(C)C)s1 -US05559266,1,CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)[O-])c1I.CCOC(=O)OC(C)Cl>>CCOC(=O)OC(C)OC(=O)c1c(I)c(NC(C)=O)c(I)c(NC(C)=O)c1I -US20100256092A1,1,C1=COCCC1.COC(=O)CCC(=O)c1ccc(O)cc1O>>COC(=O)CCC(=O)c1ccc(OC2CCCCO2)cc1O -US04536507,8,N#Cc1ccc2c(c1)Sc1ccc(F)cc1C=C2.O=C(OO)c1cccc(Cl)c1>>N#Cc1ccc2c(c1)S(=O)c1ccc(F)cc1C=C2 -US06204264B1,7,CN(C)CCCNc1ccc(C(=O)N(C)C)cc1[N+](=O)[O-]>>CN(C)CCCNc1ccc(C(=O)N(C)C)cc1N -US04144340,1,Cn1c(=O)c2c(ncn2CCCN)n(C)c1=O.OC(CCl)COc1ccccc1>>Cn1c(=O)c2c(ncn2CCCNCC(O)COc2ccccc2)n(C)c1=O -US20120283242A1,2,Cc1cc(/C=C/C(=O)O)cc(C)c1Oc1ccc(O)cn1.Clc1ccc(OCCc2ccc(CN3CCNCC3)cc2)cc1>>Cc1cc(/C=C/C(=O)N2CCN(Cc3ccc(CCOc4ccc(Cl)cc4)cc3)CC2)cc(C)c1Oc1ccc(O)cn1 -US20080207616A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1cc(N)cc(C(C)(C)C#N)c1>>COC(=O)c1cc(NC(=O)OC(C)(C)C)cc(C(C)(C)C#N)c1 -US20080051405A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cccc(COS(C)(=O)=O)n1.O=c1[nH]ncc2cc(-c3ccc(Cl)cc3)sc12>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cccc(Cn2ncc3cc(-c4ccc(Cl)cc4)sc3c2=O)n1 -US20130143863A1,1,ClCc1cncc(Br)c1.O=S1(=O)CCCCN1>>O=S1(=O)CCCCN1Cc1cncc(Br)c1 -US20060167023A1,2,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.c1cc2c(c3c1CCNC3)OCO2>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2ccc3c(c2C1)OCO3 -US07045629B2,1,NCC1CCc2ccccc2O1.O=Cc1cncc(-c2ccc(F)cc2)c1>>Fc1ccc(-c2cncc(CNCC3CCc4ccccc4O3)c2)cc1 -US20090118284A1,6,COC(=O)C1CCN(CC(=O)N2CCN(c3ccc(-c4ncccn4)cc3)CC2)C1>>O=C(O)C1CCN(CC(=O)N2CCN(c3ccc(-c4ncccn4)cc3)CC2)C1 -US05466694,1,CC(C)CN.Nc1nc(Cl)cc(Cl)n1>>CC(C)CNc1cc(Cl)nc(N)n1 -US20070197821A1,2,CCOC(=O)C(CC)CN[C@@H](C)C(=O)O.O=C(Cl)OCc1ccccc1>>CCOC(=O)C(CC)CN(C(=O)OCc1ccccc1)[C@@H](C)C(=O)O -US05726187,1,C#CCBr.COC(=O)c1cc2ccccc2cc1O>>C#CCOc1cc2ccccc2cc1C(=O)OC -US20090197877A1,6,CCNC(=O)Nc1nc2cc(OCc3ccccc3)cc(-c3ccc(C#N)cn3)c2s1>>CCNC(=O)Nc1nc2cc(O)cc(-c3ccc(C#N)cn3)c2s1 -US07754745B2,1,COC(=O)c1cnc(Br)s1.FC(F)(F)c1ccccc1O[C@H]1CCNC1>>COC(=O)c1cnc(N2CC[C@H](Oc3ccccc3C(F)(F)F)C2)s1 -US07375099B2,2,CN1C(=O)C(N)c2ccccc2-c2ccccc21.COC(C(=O)O)C(=O)NCc1cc(F)cc(F)c1>>COC(C(=O)NCc1cc(F)cc(F)c1)C(=O)NC1C(=O)N(C)c2ccccc2-c2ccccc21 -US08962654B2,2,C[C@@H]1N[C@@H](CO)Cc2c(CCC(C)(C)O)cccc21.O=C(O)Cc1ccccc1Cl>>C[C@H]1c2cccc(CCC(C)(C)O)c2C[C@H](CO)N1C(=O)Cc1ccccc1Cl -US20080287460A1,3,C#Cc1ccc(F)c(Br)c1.FS(F)(F)(F)(F)c1cccc(I)c1>>Fc1ccc(C#Cc2cccc(S(F)(F)(F)(F)F)c2)cc1Br -US08063240B2,3,CCOP(=O)(CC(=O)c1cc2ccccc2s1)OCC.O=C[C@@H]1[C@H]2CC(=O)O[C@H]2C[C@H]1OC(=O)c1ccccc1>>O=C1C[C@H]2[C@H](C[C@@H](OC(=O)c3ccccc3)[C@@H]2/C=C/C(=O)c2cc3ccccc3s2)O1 -US08580968B2,2,C1COCCN1.O=C(O)c1ccc2nc(N3CC[C@@H](N4CCCCC4)C3)sc2c1>>O=C(c1ccc2nc(N3CC[C@@H](N4CCCCC4)C3)sc2c1)N1CCOCC1 -US07399775B2,1,ClCc1cscn1.O=S([O-])c1ccc(Cl)cc1>>O=S(=O)(Cc1cscn1)c1ccc(Cl)cc1 -US04931083,1,CCOC(=O)C(C)Br.Oc1ncn(-c2cccc(C(F)(F)F)c2)n1>>CCOC(=O)C(C)Oc1ncn(-c2cccc(C(F)(F)F)c2)n1 -US20070293521A1,7,CCOC(=O)c1nc(Nc2ccc3c(c2)OCCO3)nc(Nc2ccc3c(c2)OCCO3)c1[N+](=O)[O-]>>CCOC(=O)c1nc(Nc2ccc3c(c2)OCCO3)nc(Nc2ccc3c(c2)OCCO3)c1N -US20070049603A1,9,CCOC(=O)c1sc2cnccc2c1Nc1ccc(Cl)cc1.N>>NC(=O)c1sc2cnccc2c1Nc1ccc(Cl)cc1 -US07179817B2,1,COC(=O)CCc1ccc(O)cc1.OCCCCCc1ccccc1>>COC(=O)CCc1ccc(OCCCCCc2ccccc2)cc1 -US20100076014A1,6,COC(=O)C(C)(C)C1(c2ccc3c(cnn3-c3ccc(F)cc3)c2)CCCCC1>>CC(C)(C(=O)O)C1(c2ccc3c(cnn3-c3ccc(F)cc3)c2)CCCCC1 -US20040138223A1,2,COc1ccc(CNc2ccc(C(C)C)cc2)cc1.COc1ccc2c(c1)C(C(=O)O)CCC2>>COc1ccc(CN(C(=O)C2CCCc3ccc(OC)cc32)c2ccc(C(C)C)cc2)cc1 -US07576100B2,6,COc1ccc2c(c1)N(C[C@H](C)CO[Si](C)(C)C(C)(C)C)C(=O)CO2>>COc1ccc2c(c1)N(C[C@H](C)CO)C(=O)CO2 -US20090270623A1,2,CNOC.COc1cc(C(=O)O)ccc1-n1cnc(C)c1>>COc1cc(C(=O)N(C)OC)ccc1-n1cnc(C)c1 -US20110098301A1,1,Nc1nc(Nc2ccc(Oc3ccnc(Cl)c3)cc2)cc(-c2ccccc2)n1.OCCN1CCOCC1>>Nc1nc(Nc2ccc(Oc3ccnc(OCCN4CCOCC4)c3)cc2)cc(-c2ccccc2)n1 -US04051248,7,N#CC1(Nc2ccccc2)CCN(CC2CCc3ccccc3C2=O)CC1>>N#CC1(Nc2ccccc2)CCN(CC2CCc3ccccc3C2O)CC1 -US20060252797A1,2,CCC(=O)OC(=O)CC.O=C(O)C1(Nc2ccccc2)CCN(Cc2ccccc2)CC1>>CCC(=O)N(c1ccccc1)C1(C(=O)O)CCN(Cc2ccccc2)CC1 -US04931436,2,CCN(CC)CCC1CCCCN1.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>CCN(CC)CCC1CCCCN1C(=O)N1c2ccccc2C(=O)Nc2cccnc21 -US20130137852A1,6,CC(NC(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F>>CC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F -US20150080393A1,1,CCOC(=O)[C@@H]1CC2(CCNCC2)CN1C(=O)OCc1ccccc1.Cc1ccn(-c2cc(Cl)ccc2[C@@H](Oc2cc(Cl)nc(N)n2)C(F)(F)F)n1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(Cl)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OCc1ccccc1 -US04886835,1,CCOC(=O)CS.Cc1cccc(CBr)c1>>CCOC(=O)CSCc1cccc(C)c1 -US07368471B2,6,CCOC(=O)C(=O)c1cn(Cc2ccc(C(C)(C)C)cc2)c2ccc(-c3ccc(OC(F)(F)F)cc3)cc12>>CC(C)(C)c1ccc(Cn2cc(C(=O)C(=O)O)c3cc(-c4ccc(OC(F)(F)F)cc4)ccc32)cc1 -US20090247559A1,9,CCOC(=O)C1CCN(Cc2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)C1.N>>NC(=O)C1CCN(Cc2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)C1 -US20050187264A1,2,COc1ccccc1CCN.O=C(O)/C=C/c1cccnc1>>COc1ccccc1CCNC(=O)/C=C/c1cccnc1 -US05374641,6,CCOC(=O)N(CC(Cc1cccnc1)c1ccc(OCOC)cc1)S(=O)(=O)c1ccc(Cl)cc1>>CCOC(=O)N(CC(Cc1cccnc1)c1ccc(O)cc1)S(=O)(=O)c1ccc(Cl)cc1 -US20150246906A1,1,CC(C)(C)OC(=O)NCC1CNCCO1.FC(F)(F)c1ccc(Br)cc1>>CC(C)(C)OC(=O)NCC1CN(c2ccc(C(F)(F)F)cc2)CCO1 -US08501746B2,2,COc1cc(C(=O)O)ccn1.Nc1ccccc1>>COc1cc(C(=O)Nc2ccccc2)ccn1 -US20110028467A1,7,CC1(C)Oc2ccncc2NC1=O>>CC1(C)CNc2cnccc2O1 -US06166011,2,CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)O.C[C@H]1CCC[C@@H](C)N1CCN>>C[C@H]1CCC[C@@H](C)N1CCNC(=O)[C@@H]1CCCCN1C(=O)OC(C)(C)C -US04159331,1,Clc1ccc2c(Cl)ccnc2c1.Nc1ccc(S(=O)(=O)N2CCN(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)cc1>>O=S(=O)(c1ccc(Nc2ccnc3cc(Cl)ccc23)cc1)N1CCN(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US20080280917A1,1,COc1ccc2c(OCCBr)ccnc2c1.O=c1ccc(Cl)n[nH]1>>COc1ccc2c(OCCn3nc(Cl)ccc3=O)ccnc2c1 -US05854242,7,N=C(N)NCCc1ccc(OCCC2Oc3ccc([N+](=O)[O-])cc3N(Cc3cccc(Cl)c3)C2=O)cc1>>N=C(N)NCCc1ccc(OCCC2Oc3ccc(N)cc3N(Cc3cccc(Cl)c3)C2=O)cc1 -US20050004174A1,2,Nc1ccc2[nH]ncc2c1.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc2[nH]ncc2c1)OCc1ccccc1 -US07105544B2,2,CCCC(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.O=C(O)C(c1ccc(F)cc1)c1ccc(F)cc1>>CCCC(=O)Nc1cccc(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c1 -US20080318923A1,2,COc1ccc(C)cc1C1(N2CCN(C(=O)OC(C)(C)C)CC2C(=O)N(C)C)C(=O)Nc2ccc(Cl)cc21.COc1ccc(S(=O)(=O)Cl)c(OC(F)(F)F)c1>>COc1ccc(S(=O)(=O)N2C(=O)C(c3cc(C)ccc3OC)(N3CCN(C(=O)OC(C)(C)C)CC3C(=O)N(C)C)c3cc(Cl)ccc32)c(OC(F)(F)F)c1 -US20130131050A1,1,CCOC(=O)CCCN.COc1ccc(C=O)c(OC)c1>>CCOC(=O)CCCNCc1ccc(OC)cc1OC -US20050010031A1,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)O.COCC1CN(C(Cc2ccc3ccccc3c2)C(=O)OC)CCN1>>COCC1CN(C(Cc2ccc3ccccc3c2)C(=O)OC)CCN1C(=O)C(Cc1ccc(F)cc1)NC(=O)OC(C)(C)C -US20060211712A1,6,CS(=O)c1csc(-n2c(=O)n(CC(=O)OC(C)(C)C)c3ccccc32)n1>>CS(=O)c1csc(-n2c(=O)n(CC(=O)O)c3ccccc32)n1 -US05273986,7,CCOC(=O)c1nc(C2CCCCCC2)cs1>>OCc1nc(C2CCCCCC2)cs1 -US20040242604A1,1,C1COCCN1.Cc1cc(Nc2ncnc3cnc(F)cc23)ccc1Oc1ccc(C(=O)OC(C)(C)C)cc1>>Cc1cc(Nc2ncnc3cnc(N4CCOCC4)cc23)ccc1Oc1ccc(C(=O)OC(C)(C)C)cc1 -US20100029657A1,6,CCN1C2CCC1CC(c1ccnc3c(-c4ccnc(OC)c4)c(-c4ccncc4)nn13)C2>>CCN1C2CCC1CC(c1ccnc3c(-c4ccnc(O)c4)c(-c4ccncc4)nn13)C2 -US20080153850A1,6,CCOC(=O)C1CCN(c2ncccc2-c2ccc(Cl)c(C(=O)NCC34CC5CC(CC(C5)C3)C4)c2)CC1>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(-c2cccnc2N2CCC(C(=O)O)CC2)ccc1Cl -US20110172245A1,2,Nc1nc2ccc(O)cc2s1.O=C(Cl)C1CC1>>O=C(Nc1nc2ccc(O)cc2s1)C1CC1 -US04599333,1,CC(C)(N)CCO.Clc1ccc(Cl)nn1>>CC(C)(N)CCOc1ccc(Cl)nn1 -US20090186886A1,7,COCCCN(C)CC#N>>COCCCN(C)CCN -US08377923B2,1,CCOC(=O)CBr.Cn1c(-c2ccc(O)cc2C(F)(F)F)nnc1C(C)(C)Oc1c(F)cc(F)cc1F>>CCOC(=O)COc1ccc(-c2nnc(C(C)(C)Oc3c(F)cc(F)cc3F)n2C)c(C(F)(F)F)c1 -US08741934B2,2,Nc1nc[nH]n1.O=C(NCc1ccc(C(F)(F)F)cc1)c1ccc(S(=O)(=O)Cl)cc1>>O=C(NCc1ccc(C(F)(F)F)cc1)c1ccc(S(=O)(=O)Nc2nc[nH]n2)cc1 -US20030139418A1,1,CCNCc1ccccc1N.NC(=O)c1ccc(Cl)nn1>>CCN(Cc1ccccc1N)c1ccc(C(N)=O)nn1 -US20060211740A1,3,C#CC(C)(C)O.CC(C)(C)OC(=O)c1cc(Br)cc(N(c2ccccc2)S(C)(=O)=O)c1>>CC(C)(O)C#Cc1cc(C(=O)OC(C)(C)C)cc(N(c2ccccc2)S(C)(=O)=O)c1 -US20110053912A1,6,COC(=O)C12CC3CC(CC(Nc4ncc(C(=O)N5CCS(=O)(=O)CC5)c(C(F)(F)F)n4)(C3)C1)C2>>O=C(c1cnc(NC23CC4CC(C2)CC(C(=O)O)(C4)C3)nc1C(F)(F)F)N1CCS(=O)(=O)CC1 -US05036059,3,CC(=O)CP1(=O)OCCCO1.O=Cc1cccc([N+](=O)[O-])c1>>CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)P1(=O)OCCCO1 -US20050075326A1,6,CC(C)(C)OC(=O)NC(CCN1CCC2(CC1)CCN(Cc1ccc(Br)cc1)C2=O)c1ccccc1>>NC(CCN1CCC2(CC1)CCN(Cc1ccc(Br)cc1)C2=O)c1ccccc1 -US20060094707A1,3,C=C(CC(=O)OCC)C(=O)OCC.Cc1c(N)ccc(I)c1[N+](=O)[O-]>>CCOC(=O)C/C(=C\c1ccc(N)c(C)c1[N+](=O)[O-])C(=O)OCC -US20090093633A1,6,CCc1nnn([C@H]2C[C@@H](n3cnc4c(NCC(c5ccc(O)cc5)c5ccc(O)cc5)nc(N5CC[C@@H](NC(=O)OC(C)(C)C)C5)nc43)[C@H](O)[C@@H]2O)n1>>CCc1nnn([C@H]2C[C@@H](n3cnc4c(NCC(c5ccc(O)cc5)c5ccc(O)cc5)nc(N5CC[C@@H](N)C5)nc43)[C@H](O)[C@@H]2O)n1 -US06849625B2,1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCOCC1.Nc1c(Cl)ccc2c(Br)coc12>>COc1cc2c(Nc3c(Cl)ccc4c(Br)coc34)ncnc2cc1OCCCN1CCOCC1 -US20090221555A1,7,N#Cc1ccc([N+](=O)[O-])cc1N>>NCc1ccc([N+](=O)[O-])cc1N -US20140323468A1,2,CC(=O)O.N#Cc1c(-c2cnc3c(c2)CCCN3C(N)=O)cncc1C1CCNCC1>>CC(=O)N1CCC(c2cncc(-c3cnc4c(c3)CCCN4C(N)=O)c2C#N)CC1 -US06965048B2,6,COC(=O)CCO[C@@H]1CC[C@@H](N(C)C(=O)OC(C)(C)C)CC1>>CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](OCCC(=O)O)CC1 -US08431695B2,1,NCc1cccc(-c2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)c1.O=C1CCCC1>>Nc1ncnn2c(-c3cccc(CNC4CCCC4)c3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12 -US06399603B1,6,O=[N+]([O-])c1cc(C2OCCO2)c2nc(Nc3ccc(Cl)c(Cl)c3)nc(O)c2c1>>O=Cc1cc([N+](=O)[O-])cc2c(O)nc(Nc3ccc(Cl)c(Cl)c3)nc12 -US20130267538A1,7,Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(CO)O2 -US20110112140A1,3,Cc1noc(C)c1B1OC(C)(C)C(C)(C)O1.O=C(O)Nc1cccc(I)c1>>Cc1noc(C)c1-c1cccc(NC(=O)O)c1 -US20070219235A1,7,Nc1cc(Cl)c(C(=O)Nc2ccc3cn[nH]c3c2)cc1[N+](=O)[O-]>>Nc1cc(Cl)c(C(=O)Nc2ccc3cn[nH]c3c2)cc1N -US05965555,3,C#CCN(C)C.CCCn1cnc2c1c(=O)n(CCC(C)=O)c(=O)n2C>>CCCn1cnc2c1c(=O)n(CCC(C)(O)C#CCN(C)C)c(=O)n2C -US20080234255A1,1,COC(=O)C(C)(C)CN.O=C1CCCC1>>COC(=O)C(C)(C)CNC1CCCC1 -US20110201687A1,2,Nc1cccc(C(=O)Nc2c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)c1.O=C(Cl)c1cccnc1Cl>>O=C(Nc1c(I)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C(F)(F)F)c1cccc(NC(=O)c2cccnc2Cl)c1 -US20100105655A1,2,COc1cc(OC2CCNCC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1.CS(=O)(=O)Cl>>COc1cc(OC2CCN(S(C)(=O)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 -US05250732,2,CSCCC(=O)O.NC1(c2ccccc2Cl)CCC=CC1=O>>CSCCC(=O)NC1(c2ccccc2Cl)CCC=CC1=O -US20150232465A1,2,C[C@@H](CO)Nc1cnc(Br)cc1N.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2cc(Br)ncc2N[C@@H](C)CO)cc1 -US05492915,2,C1CCNC1.O=C(O)CCCCCOc1cc(-c2ccccc2)c2ccccc2n1>>O=C(CCCCCOc1cc(-c2ccccc2)c2ccccc2n1)N1CCCC1 -US20040087798A1,6,O=C(Nc1ccnc(N2CCN(Cc3ccccc3)CC2)c1)c1cccc2c1Cc1ccccc1-2>>O=C(Nc1ccnc(N2CCNCC2)c1)c1cccc2c1Cc1ccccc1-2 -US20150004181A1,2,CN.COC(=O)CSc1cccc(C(OC2CCN(C)CC2)c2nc3ccccc3s2)c1>>CNC(=O)CSc1cccc(C(OC2CCN(C)CC2)c2nc3ccccc3s2)c1 -US04604390,6,COc1ccc2oc3c([N+](=O)[O-])ccc(Cl)c3c(=O)c2c1>>O=c1c2cc(O)ccc2oc2c([N+](=O)[O-])ccc(Cl)c12 -US08471004B2,2,C[C@H]1C(=O)N2C(CN1C(=O)OCc1ccccc1)OC[C@@H]2CC(=O)O.O[C@@H]1CNCCC12CC2>>C[C@H]1C(=O)N2C(CN1C(=O)OCc1ccccc1)OC[C@@H]2CC(=O)N1CCC2(CC2)[C@H](O)C1 -US20150148342A1,1,O=[N+]([O-])c1c(F)ccc(Br)c1F.Oc1ccccc1>>O=[N+]([O-])c1c(F)ccc(Br)c1Oc1ccccc1 -US20030134859A1,1,CCCCCCNc1ccc(-c2ccc(NC(=O)c3cc([N+](=O)[O-])ccc3Cl)cc2)cc1.CI>>CCCCCCN(C)c1ccc(-c2ccc(NC(=O)c3cc([N+](=O)[O-])ccc3Cl)cc2)cc1 -US08901141B2,6,COC(=O)c1cccc(N)c1NC(=O)OC(C)(C)C>>COC(=O)c1cccc(N)c1N -US20110086858A1,1,COC(=O)c1ccc(Nc2nc(Cl)nc(OCC(F)(F)F)n2)cc1.NCc1ccc(O)cc1>>COC(=O)c1ccc(Nc2nc(NCc3ccc(O)cc3)nc(OCC(F)(F)F)n2)cc1 -US20150266878A1,3,CC1(C)OB(c2ccc3[nH]c(=O)[nH]c3c2)OC1(C)C.OC[C@H](Nc1cncc(Br)c1)c1ccccc1>>O=c1[nH]c2ccc(-c3cncc(N[C@@H](CO)c4ccccc4)c3)cc2[nH]1 -US20130059853A1,2,CC(=O)Cl.COc1ccc(-c2cccc3c2CCC3=O)c(OCC2(CN)COC2)c1OC>>COc1ccc(-c2cccc3c2CCC3=O)c(OCC2(CNC(C)=O)COC2)c1OC -US06586421B2,2,CC(C)(C)OC(=O)N1CCc2c(n(CCN)c3ccccc23)CC1.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCc2c(n(CCNC(=O)c3ccccc3)c3ccccc23)CC1 -US20150065705A1,1,CC1(C)OB(C2=CCNCC2)OC1(C)C.O=c1nc(Cl)ncn1Cc1ccc(Cl)cc1>>CC1(C)OB(C2=CCN(c3ncn(Cc4ccc(Cl)cc4)c(=O)n3)CC2)OC1(C)C -US20150225399A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O.NCCOc1ccccc1>>O=C(NCCOc1ccccc1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O -US06362352B1,1,BrCCCCCCBr.COC(=O)CCS>>COC(=O)CCSCCCCCCBr -US20130274266A1,2,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)Cn2c1nc(Cl)c2C#N.O=C(O)c1ccn(C(F)F)n1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(NC(=O)c3ccn(C(F)F)n3)ccc2F)Cn2c1nc(Cl)c2C#N -US20060241296A1,1,CC(C)(C)OC(=O)Nc1cc(C(F)(F)F)ccc1-c1cc(Cl)ncn1.Nc1cccc2c1CC(O)C2>>CC(C)(C)OC(=O)Nc1cc(C(F)(F)F)ccc1-c1cc(Nc2cccc3c2CC(O)C3)ncn1 -US20100168005A1,1,CC(C)O.O=C(O)c1cnc(Cl)c(Cl)c1>>CC(C)Oc1ncc(C(=O)O)cc1Cl -US20140142119A1,2,N#CC1(C(=O)O)CC1.N[C@@H]1CCC[C@H](Nc2cc(-c3c[nH]c4ncc(F)cc34)ccc2F)C1>>N#CC1(C(=O)N[C@@H]2CCC[C@H](Nc3cc(-c4c[nH]c5ncc(F)cc45)ccc3F)C2)CC1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@@H](c2cccs2)NC1=O.O=C(O)c1cc(-c2ccc(F)cc2)on1>>CC(C)C[C@H]1C(=O)N[C@H](c2cccs2)CN1C(=O)c1cc(-c2ccc(F)cc2)on1 -US08791272B2,3,COC(=O)Cc1c(C)nn(Cc2ccc(C=O)cc2)c1C.[Mg+]Cc1ccccc1>>COC(=O)Cc1c(C)nn(Cc2ccc(C(O)Cc3ccccc3)cc2)c1C -US20050250836A1,1,C[C@H]1CNC[C@@H](C)N1.O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c(Br)cn1CCCBr>>C[C@H]1CN(CCCn2cc(Br)c3c4c(c(-c5ccccc5Cl)cc32)C(=O)NC4=O)C[C@@H](C)N1 -US20090156582A1,1,COC(=O)c1n[nH]cc1[N+](=O)[O-].ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1[N+](=O)[O-] -US07601716B2,2,NCc1cccc2ccccc12.O=C(O)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1>>O=C(NCc1cccc2ccccc12)c1cccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)c1 -US20120094971A1,6,CCOC(=O)/C=C/CCCO[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)OCCC/C=C/C(=O)O -US07517875B2,6,COC(=O)c1cccc2[nH]c(NCC3CCN(C(=O)OC(C)(C)C)CC3)nc12>>COC(=O)c1cccc2[nH]c(NCC3CCNCC3)nc12 -US20060058308A1,1,CC(N)c1ccc(F)cc1.Nc1ccc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(Cl)n3)c2n1>>CC(Nc1nc(Oc2cccc3ccc(N)nc23)cc(-c2ccc(C(F)(F)F)cc2)n1)c1ccc(F)cc1 -US08580971B2,2,Cn1cc(C(=O)O)c(C(F)F)n1.Nc1ccc(F)cc1-c1ccc(Cl)c(F)c1>>Cn1cc(C(=O)Nc2ccc(F)cc2-c2ccc(Cl)c(F)c2)c(C(F)F)n1 -US20130190307A1,9,Clc1cnc2ccc(Br)cc2n1.NN>>NNc1cnc2ccc(Br)cc2n1 -US20100041760A1,2,CN.O=S(=O)(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CNS(=O)(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US06110956,9,Nc1c(OCCCl)cc(Cl)cc1[N+](=O)[O-].[N-]=[N+]=[N-]>>[N-]=[N+]=NCCOc1cc(Cl)cc([N+](=O)[O-])c1N -US07378417B2,2,Cc1ccc(S(=O)(=O)NC(C)(C)CO)cc1N.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>Cc1ccc(S(=O)(=O)NC(C)(C)CO)cc1NC(=O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12 -US20080045521A1,1,Brc1cccc(CCOC2CCCCO2)n1.NC1CCCC1>>c1cc(CCOC2CCCCO2)nc(NC2CCCC2)c1 -US20040110764A1,8,N#Cc1ccc(C(CCCO)n2cncc2C(=O)N2CCN(c3cccc(Cl)c3)C(=O)C2)cc1>>N#Cc1ccc(C(CCC=O)n2cncc2C(=O)N2CCN(c3cccc(Cl)c3)C(=O)C2)cc1 -US20090075980A1,2,COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)N.O=C(Cl)c1cccnc1>>COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)NC(=O)c1cccnc1 -US20140303127A1,1,N#Cc1ccc(F)c([N+](=O)[O-])c1.NCCCO>>N#Cc1ccc(NCCCO)c([N+](=O)[O-])c1 -US05064861,6,C=CCc1c(OCC(=O)OCC)cccc1C(F)(F)F>>C=CCc1c(OCC(=O)O)cccc1C(F)(F)F -US20100256356A1,6,COc1ccc(Cn2nc(C)c3c(Oc4ccc(NC(=O)Nc5ccccn5)cc4F)ccnc32)cc1>>Cc1n[nH]c2nccc(Oc3ccc(NC(=O)Nc4ccccn4)cc3F)c12 -US06713474B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Br)cc1F>>CC(C)(C)OC(=O)Nc1ccc(Br)cc1F -US20120022075A1,9,COC[C@H](C)Oc1cc(Oc2ccc(C(=O)O)cc2F)cc(-c2ccc(-c3nccs3)[nH]2)c1.N>>COC[C@H](C)Oc1cc(Oc2ccc(C(N)=O)cc2F)cc(-c2ccc(-c3nccs3)[nH]2)c1 -US20110065734A1,7,O=[N+]([O-])c1cccc(Nc2nccc(-c3cccnc3)n2)c1>>Nc1cccc(Nc2nccc(-c3cccnc3)n2)c1 -US20150166564A1,7,O=Nc1c(-c2ccccc2)nn2ccccc12>>Nc1c(-c2ccccc2)nn2ccccc12 -US20100196321A1,2,CCN(CC)C(=O)Cl.COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5C=CCCCCC[C@H](N)C(=O)N4C3)cc(-c3nc(C4CC4)cs3)nc2c1C>>CCN(CC)C(=O)N[C@H]1CCCCCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@@H](Oc3cc(-c4nc(C5CC5)cs4)nc4c(C)c(OC)ccc34)CN2C1=O -US20120101124A1,1,CCOC(CBr)OCC.COc1ccc(Br)cc1O>>CCOC(COc1cc(Br)ccc1OC)OCC -US20130230459A1,1,BrCc1ccccc1.Oc1cc(F)cc(F)c1Br>>Fc1cc(F)c(Br)c(OCc2ccccc2)c1 -US20060173204A1,2,CCOC(=O)C(Cc1ccc(OCCc2ccc(O)cc2)cc1)OCC.O=C=NCc1ccccc1>>CCOC(=O)C(Cc1ccc(OCCc2ccc(OC(=O)NCc3ccccc3)cc2)cc1)OCC -US08765730B2,3,CON(C)C(=O)CC(c1ccc(Br)cc1)c1ccccc1C(F)(F)F.Cc1cc(Br)ccn1>>Cc1cc(C(=O)CC(c2ccc(Br)cc2)c2ccccc2C(F)(F)F)ccn1 -US07189738B2,2,CC(C)(C)OC(=O)N1CCNCC1.Nc1cccc2c1C(=O)N(CC(=O)O)C2=O>>CC(C)(C)OC(=O)N1CCN(C(=O)CN2C(=O)c3cccc(N)c3C2=O)CC1 -US20150133425A1,1,CN(C)C(=O)C1CCc2c(sc3ncnc(Cl)c23)C1.[N-]=[N+]=NCCOc1cc2[nH]ncc2cc1N>>CN(C)C(=O)C1CCc2c(sc3ncnc(Nc4cc5cn[nH]c5cc4OCCN=[N+]=[N-])c23)C1 -US20090227591A1,2,NS(=O)(=O)c1ccccc1.O=C(O)c1cccc(C2=C(c3cc(Cl)ccc3OCc3ccc(F)cc3F)CCC2)n1>>O=C(NS(=O)(=O)c1ccccc1)c1cccc(C2=C(c3cc(Cl)ccc3OCc3ccc(F)cc3F)CCC2)n1 -US05302720,7,CS(=O)(=O)c1cccc(-c2ccccc2[N+](=O)[O-])c1>>CS(=O)(=O)c1cccc(-c2ccccc2N)c1 -US05665754,2,COC(=O)Cl.COc1ccc(C2CNCC2CO)cc1OC1CCCC1>>COC(=O)N1CC(CO)C(c2ccc(OC)c(OC3CCCC3)c2)C1 -US06432950B1,1,Clc1cc2c(Cl)nc(-c3ccno3)nc2s1.NCc1ccc(Cl)c(Cl)c1>>Clc1cc2c(NCc3ccc(Cl)c(Cl)c3)nc(-c3ccno3)nc2s1 -US20120058984A1,1,COc1ccc2nc(Nc3cc(C(F)(F)c4ccc(F)cc4)nc(Cl)n3)sc2c1.Nc1ccc(CC(=O)O)cc1>>COc1ccc2nc(Nc3cc(C(F)(F)c4ccc(F)cc4)nc(Nc4ccc(CC(=O)O)cc4)n3)sc2c1 -US05512207,3,CCCCCCCCOc1ccc(B(O)O)cn1.Clc1cnc(-c2ccc(OCc3ccccc3)cc2)cn1>>CCCCCCCCOc1ccc(-c2cnc(-c3ccc(OCc4ccccc4)cc3)cn2)cn1 -US20130040930A1,1,C[C@@H]1CCS(=O)(=O)N1.Cc1cnc(N2CCN(C(=O)c3c(F)cc(I)cc3F)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3c(F)cc(N4[C@H](C)CCS4(=O)=O)cc3F)CC2)c(C)c1 -US20060287323A1,1,BrCc1ccccc1.O=c1[nH]ncc(Cl)c1Cl>>O=c1c(Cl)c(Cl)cnn1Cc1ccccc1 -US09084794B2,1,NC(=O)C(Br)c1ccc(Br)cc1F.O=C1COC2(CCNCC2)CN1C1(CO)CC1>>NC(=O)C(c1ccc(Br)cc1F)N1CCC2(CC1)CN(C1(CO)CC1)C(=O)CO2 -US08232287B2,2,CCCCOC(=O)Cl.CS(=O)(=O)c1ccc2c(c1)CCN2c1cc(OC2CCNCC2)ncn1>>CCCCOC(=O)N1CCC(Oc2cc(N3CCc4cc(S(C)(=O)=O)ccc43)ncn2)CC1 -US05665718,4,O=C(CN1C(=O)c2ccccc2C1=O)NNC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1sccc1-2>>O=C1c2ccccc2C(=O)N1Cc1nnc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2sccc2-3)o1 -US05681838,2,CC(C)(C)OC(=O)NCCCNCC(=O)O.COC(=O)C(N=C=O)c1ccccc1>>COC(=O)C(NC(=O)N(CCCNC(=O)OC(C)(C)C)CC(=O)O)c1ccccc1 -US06951879B2,3,C#CC1(N(C)CC=C)CCCC1.O=S(=O)(Oc1ccc2c(-c3ccc(C(F)(F)F)cc3)nsc2c1)C(F)(F)F>>C=CCN(C)C1(C#Cc2ccc3c(-c4ccc(C(F)(F)F)cc4)nsc3c2)CCCC1 -US04123256,2,CON(C)C(=O)Cl.Nc1ccc(OCc2ccc(Cl)c(Cl)c2)cc1>>CON(C)C(=O)Nc1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 -US08334317B2,1,CI.c1ccc(-c2c[nH]cn2)cc1>>Cn1cnc(-c2ccccc2)c1 -US20150141383A1,2,CC(C)CN(CC(O)C(N)Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1.O=C(O)O[C@H]1CO[C@H]2OCC[C@@H]12>>CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc(N)cc1 -US20150225405A1,6,O=C(c1ccc(Cn2c3ccc(F)cc3c3c2cnn3C2CCCCO2)cc1)N1CCOCC1>>O=C(c1ccc(Cn2c3ccc(F)cc3c3[nH]ncc32)cc1)N1CCOCC1 -US06458772B1,6,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OCCCC(=O)OCc1ccccc1>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OCCCC(=O)O -US04973592,2,O=C(O)C(O)(c1ccccc1)C1CCCCC1.OCCNc1ncccn1>>O=C(OCCNc1ncccn1)C(O)(c1ccccc1)C1CCCCC1 -US08293757B2,6,CCOC(=O)C(CO)c1ccc(Nc2ncc(-c3ccc(OC(F)F)cc3)cn2)cc1>>O=C(O)C(CO)c1ccc(Nc2ncc(-c3ccc(OC(F)F)cc3)cn2)cc1 -US20060052365A1,8,O=C(N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)c2ccco2)CC1O)c1ccco1>>O=C(N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)c2ccco2)CC1=O)c1ccco1 -US04367235,2,Cc1ccc(OCC(O)CNC(C)(C)C)c2[nH]c(=O)[nH]c12.O=C(O)c1ccccc1>>Cc1ccc(OCC(CNC(C)(C)C)OC(=O)c2ccccc2)c2[nH]c(=O)[nH]c12 -US20080076763A1,1,CC=O.CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@@H]3CNCCO3)c21>>CCN1CCO[C@H](COc2cnc(C#CC(C)(C)O)c3nc(-c4nonc4N)n(CC)c23)C1 -US20050256164A1,1,C1COCCN1.COC(=O)CBr>>COC(=O)CN1CCOCC1 -US20110076291A1,6,CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CN(CCOC4CCCCO4)C3)ccc1-2>>CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CN(CCO)C3)ccc1-2 -US05644024,1,C=CCOC(=O)c1ccccc1I.COC(=O)[C@]1(NC(=O)OC(C)(C)C)CCc2cccc(O)c2C1>>C=CCOC(=O)c1ccccc1Oc1cccc2c1C[C@](NC(=O)OC(C)(C)C)(C(=O)OC)CC2 -US04596819,8,Cc1ccc(S(=O)(=O)N2CCCC2CO)cc1>>Cc1ccc(S(=O)(=O)N2CCCC2C=O)cc1 -US20070244154A1,7,Cc1nc2c3c(c(C(=O)N(C)C)cc2n1C)C(=O)[C@H](O)[C@@H](c1ccccc1)N3>>Cc1nc2c3c(c(C(=O)N(C)C)cc2n1C)C(O)[C@H](O)[C@@H](c1ccccc1)N3 -US07863300B2,3,CCc1ccc(C(Br)COc2ccc(C=O)cc2)nc1.O=C1CSC(=O)N1>>CCc1ccc(C(Br)COc2ccc(C=C3SC(=O)NC3=O)cc2)nc1 -US20050065118A1,6,COC(=O)Cc1cccc(Oc2cccc(-c3nnc(Nc4ccc(Cl)c(Cl)c4)s3)c2)c1>>O=C(O)Cc1cccc(Oc2cccc(-c3nnc(Nc4ccc(Cl)c(Cl)c4)s3)c2)c1 -US08877778B2,2,Cc1nc(-c2ccc(C(=O)O)cc2)no1.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1>>Cc1nc(-c2ccc(C(=O)N[C@@H]3CC[C@@H](CCN4CCC(c5cccc6c5CCO6)CC4)CC3)cc2)no1 -US20150057433A1,2,C#CCN.O=C(O)Cc1ccc(CBr)cc1>>C#CCNC(=O)Cc1ccc(CBr)cc1 -US08293735B2,1,CC(C)(C)OC(=O)N1CC2CNCC2C1.Clc1nc(N2CCOCC2)c2sc(CBr)cc2n1>>CC(C)(C)OC(=O)N1CC2CN(Cc3cc4nc(Cl)nc(N5CCOCC5)c4s3)CC2C1 -US20030096838A1,2,CC(C)C(=O)Cl.NNc1ccc(Br)cn1>>CC(C)C(=O)NNc1ccc(Br)cn1 -US06040339,2,CCCCCC(CC(=O)Nc1cc(C(N)=O)ccc1C(C)(C)C)c1ccc(OC)cc1OC.O=C(O)CCC(=O)OCc1ccccc1>>CCCCCC(CC(=O)Nc1cc(C(=O)NC(=O)CCC(=O)OCc2ccccc2)ccc1C(C)(C)C)c1ccc(OC)cc1OC -US08252795B2,1,CCN(CC)c1ccc(N)cc1.COc1ccc(CN(c2cc(Cl)nn3c(C#N)cnc23)C2CC2)cc1>>CCN(CC)c1ccc(Nc2cc(N(Cc3ccc(OC)cc3)C3CC3)c3ncc(C#N)n3n2)cc1 -US08501732B2,2,COc1ccc(N=C=O)cc1.NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O>>COc1ccc(NC(=O)NCc2cn(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1 -US08202885B2,2,CN(CCCc1nc2cc(Cl)c(Cl)cc2[nH]1)CCC1(O)CC2CCC1C=C2c1ccccc1.O=C(Cl)C1CC1>>CN(CCCc1nc2cc(Cl)c(Cl)cc2[nH]1)CC[C@]1(OC(=O)C2CC2)C[C@H]2CC[C@@H]1C=C2c1ccccc1 -US20130261178A1,1,CCOCCOc1ccc(O)cc1.ClCC1CO1>>CCOCCOc1ccc(OCC2CO2)cc1 -US06107458,6,CCCCCCCCOc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CCCCCCCCOc1ccc(N2CCNCC2)cc1 -US20070155740A1,1,CC[C@H](COC)n1cc(Br)nc(Br)c1=O.Clc1cc(Cl)c2c(c1)CCN2>>CC[C@H](COC)n1cc(Br)nc(N2CCc3cc(Cl)cc(Cl)c32)c1=O -US20070185168A1,9,OC1(c2cccs2)CCNCC1>>c1csc(C2CCNCC2)c1 -US05283248,1,NC1CC1.O=[N+]([O-])c1cc(F)c(Cl)cc1F>>O=[N+]([O-])c1cc(F)c(Cl)cc1NC1CC1 -US20060019985A1,1,CC(C)(C)OC(=O)N1CCC2(CCNC2)CC1.CCOC(=O)c1cc(C2CC2)c2c(C)c(Cl)c(F)cn2c1=O>>CCOC(=O)c1cc(C2CC2)c2c(C)c(N3CCC4(CCN(C(=O)OC(C)(C)C)CC4)C3)c(F)cn2c1=O -US06982348B2,2,COCc1ccc(C(=O)O)c2ccccc12.NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1>>COCc1ccc(C(=O)NC(Cc2ccc(C(F)(F)F)cc2)C(O)c2ccc(F)cc2)c2ccccc12 -US20040192686A1,1,CC(C)c1ccc2c(c1)nc(Cl)n[n+]2[O-].CCCN(CCC)CCN>>CCCN(CCC)CCNc1nc2cc(C(C)C)ccc2[n+]([O-])n1 -US20050131014A1,1,COc1cccc(F)c1C=O.Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>COc1cccc(F)c1CNc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 -US06432950B1,1,Cc1cc2c(Cl)nc(-c3cccnc3)nc2s1.NCCc1ccc2c(c1)OCCO2>>Cc1cc2c(NCCc3ccc4c(c3)OCCO4)nc(-c3cccnc3)nc2s1 -US20080318937A1,3,CC(=O)Nc1ccccc1B1OC(C)(C)C(C)(C)O1.CC(C)(C)OC(=O)N1CCC(N2c3ccccc3Oc3cc(Cl)ccc32)CC1>>CC(=O)Nc1ccccc1-c1ccc2c(c1)Oc1ccccc1N2C1CCN(C(=O)OC(C)(C)C)CC1 -US20120190677A1,6,COC(=O)c1cc(C)c2c(c1)C(C)(C)CC(c1cccc(N3CCOCC3)c1)N2>>Cc1cc(C(=O)O)cc2c1NC(c1cccc(N3CCOCC3)c1)CC2(C)C -US20110053907A1,1,COc1cccc2[nH]c(C(F)F)nc12.Clc1nc(Cl)nc(N2CCOCC2)n1>>COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)nc(N2CCOCC2)n1 -US06531479B2,9,N#CN.Nc1ccc(F)cc1F>>N=C(N)Nc1ccc(F)cc1F -US20070004771A1,1,CCN.O=[N+]([O-])c1cnc(Cl)c(Br)c1Cl>>CCNc1c([N+](=O)[O-])cnc(Cl)c1Br -US07915267B2,2,CCOC(=O)c1nc2ccc(F)cc2c(=O)[nH]1.NCc1cccc(OCCSc2nc[nH]n2)c1>>O=C(NCc1cccc(OCCSc2nc[nH]n2)c1)c1nc2ccc(F)cc2c(=O)[nH]1 -US20120114765A1,2,CCN1C[C@H](N)[C@@H](OC)C1.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>CCN1C[C@H](NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)[C@@H](OC)C1 -US04167568,7,CCCOc1ccc([N+](=O)[O-])cc1C1=NC(=O)C2=NN=NC2=N1>>CCCOc1ccc(N)cc1C1=NC(=O)C2=NN=NC2=N1 -US20150045339A1,2,C#Cc1cccc(N)c1.C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C>>C#Cc1cccc(NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)c1 -US07632829B2,1,CC1(CCl)CO1.O=C1CCN(C(=O)/C=C/c2ccc(Cl)c(Cl)c2)CCN1>>CC1(CN2CCN(C(=O)/C=C/c3ccc(Cl)c(Cl)c3)CCC2=O)CO1 -US05149524,1,C1CCNCC1.OCCCCCCCCCCCBr>>OCCCCCCCCCCCN1CCCCC1 -US05709911,7,O=C1CCC([C@@H]2CC[C@@H](c3cccc(F)c3F)CC2)CC1>>O[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](c3cccc(F)c3F)CC2)CC1 -US06313126B1,6,Fc1ccc2c(C3CCC4(CC3)OCCO4)c[nH]c2c1>>O=C1CCC(c2c[nH]c3cc(F)ccc23)CC1 -US20120101134A1,3,CC(C)Oc1ccc(-c2nc(Br)ns2)cc1Cl.CCc1c(/C=C/OC)cccc1B1OC(C)(C)C(C)(C)O1>>CCc1c(/C=C/OC)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 -US09139581B2,1,Clc1nc(Cl)c2cc[nH]c2n1.NCCCCN>>NCCCCNc1nc(Cl)nc2[nH]ccc12 -US20130018037A1,8,OCCCc1cccc(CO)c1>>O=Cc1cccc(CCCO)c1 -US04921638,9,C=C1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]2(C)[C@]1(O)C(=O)CCl>>C=C1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]2(C)[C@]1(O)C(C)=O -US20090221555A1,2,CC(=O)OC(C)=O.CC1(C)CC(N)C(=O)Nc2cc([N+](=O)[O-])ccc21>>CC(=O)NC1CC(C)(C)c2ccc([N+](=O)[O-])cc2NC1=O -US20100016287A1,6,Cc1nc2cc3c(cc2o1)CCN(C(=O)OC(C)(C)C)CC3>>Cc1nc2cc3c(cc2o1)CCNCC3 -US05232633,2,CCCCCCCCCCC(C)O.O=C(Cl)Cl>>CCCCCCCCCCC(C)OC(=O)Cl -US07101886B2,2,CC(=O)Cl.Cc1cccc(CCN2CCN(c3nsc4ccccc34)CC2)c1N>>CC(=O)Nc1c(C)cccc1CCN1CCN(c2nsc3ccccc23)CC1 -US07960369B2,3,Brc1ccc(OC2Cc3ccccc3C2)cc1.C=CC(=O)OC>>COC(=O)/C=C/c1ccc(OC2Cc3ccccc3C2)cc1 -US20150119380A1,1,CC(C)(C)OC(=O)N1CCN(c2ccc3cc(-c4cccc(F)n4)c(=O)oc3c2)CC1.CC(C)O>>CC(C)Oc1cccc(-c2cc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3oc2=O)n1 -US20140023611A1,4,O=C(O)C#CC(=O)O.[N-]=[N+]=NCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)c1>>O=C(Nc1ccc(N2CCCCC2)cc1C(=O)N/N=C/c1ccc(Cl)c(C(F)(F)F)c1)c1cccc(Cn2nnc(C(=O)O)c2C(=O)O)c1 -US09079866B2,3,CC(C)(C)NS(=O)(=O)c1ccccc1Br.CC1(C)OB(c2ccc(-c3nnc(N)s3)c(F)c2)OC1(C)C>>CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2nnc(N)s2)c(F)c1 -US08563573B2,2,CC(C)(C)c1cc2cc(N)ncc2[nH]1.O=C(O)C1(c2ccc3c(c2)OCO3)CC1>>CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ncc2[nH]1 -US07875610B2,1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CC=O)CC1.CNc1nc(Cl)c(Cl)c(N2CCNCC2)n1>>CNc1nc(Cl)c(Cl)c(N2CCN(CC[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)CC2)n1 -US20070106095A1,6,CCOC(=O)c1cc2ccc(C(CC)(CC)c3ccc(OCC(=O)C(C)(C)C)c(C)c3)cc2o1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc2cc(C(=O)O)oc2c1 -US06887877B2,6,C#CCN(C(=O)c1ccc(Cl)cc1Cl)C(Cc1ccccc1)C(=O)OC>>C#CCN(C(=O)c1ccc(Cl)cc1Cl)C(Cc1ccccc1)C(=O)O -US08188098B2,2,CC(C)CS(=O)(=O)Cl.CS(=O)(=O)c1ccc(Oc2ncnc3c2cnn3C2CCNCC2)cc1>>CC(C)CS(=O)(=O)N1CCC(n2ncc3c(Oc4ccc(S(C)(=O)=O)cc4)ncnc32)CC1 -US20060030583A1,3,COCCOc1ccc(B(O)O)cc1OCCOC.COc1ccccc1-c1c[nH]c2ncc(Br)cc12>>COCCOc1ccc(-c2cnc3[nH]cc(-c4ccccc4OC)c3c2)cc1OCCOC -US20090203676A1,1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.CS(=O)(=O)c1ccc(N2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCC(CN2CCN(c3ccc(S(C)(=O)=O)cc3)CC2)CC1 -US20050261345A1,6,CCN(CCCNC(=O)OCc1ccccc1)Cc1ccccc1OC>>CCN(CCCN)Cc1ccccc1OC -US20120101083A1,2,CC(C)(C)OC(=O)NCCC(=O)O.CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNC4)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(C(=O)CCNC(=O)OC(C)(C)C)C4)no2)cc1C#N -US20140094450A1,6,CCC(CC)n1c(Cc2ccc(Cl)s2)nc2cc(C(=O)OC)ccc21>>CCC(CC)n1c(Cc2ccc(Cl)s2)nc2cc(C(=O)O)ccc21 -US08748632B2,1,COC(=O)c1ccc(-c2cccc(CBr)c2)cc1Cl.O=c1c2ccc(O)cc2sn1C1CCCC1>>COC(=O)c1ccc(-c2cccc(COc3ccc4c(=O)n(C5CCCC5)sc4c3)c2)cc1Cl -US04296128,6,O=C(OCc1ccccc1)C(CCSc1ccccc1)C(=O)OCc1ccccc1>>O=C(O)C(CCSc1ccccc1)C(=O)OCc1ccccc1 -US20130217664A1,7,CN(c1cc2c(cn1)ncn2C)c1ccc(C#N)cc1F>>CN(c1cc2c(cn1)ncn2C)c1ccc(CN)cc1F -US05102877,6,C[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C>>C[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C -US20040002524A1,6,COc1ccc(-n2c(-c3sccc3Br)nc3ccccc32)cc1>>Oc1ccc(-n2c(-c3sccc3Br)nc3ccccc32)cc1 -US06107308,1,C(=C1CCNCC1)c1ccc2ccccc2n1.Cc1ccc(OCCCCl)c2c1NC(=O)C2(C)C>>Cc1ccc(OCCCN2CCC(=Cc3ccc4ccccc4n3)CC2)c2c1NC(=O)C2(C)C -US20050043368A1,6,CCCC[C@H](NC(=O)OC(C)(C)C)C(O)CNS(=O)(=O)c1ccccn1>>CCCC[C@H](N)[C@@H](O)CNS(=O)(=O)c1ccccn1 -US20030069167A1,9,CCCC(=O)C(C)C.NO>>CCCC(=NO)C(C)C -US06069156,6,CCCc1c(C(C)=O)c2ccc(C(=O)OC)cc2n1Cc1ccccc1Cl>>CCCc1c(C(C)=O)c2ccc(C(=O)O)cc2n1Cc1ccccc1Cl -US05864043,6,CCCCc1nc2ccc(N(C)C(=O)OCC)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2ccc(N(C)C(=O)OCC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US20100010002A1,2,CC(C)N.O=C(O)C=Cc1ccc(O)c(O)c1>>CC(C)NC(=O)/C=C/c1ccc(O)c(O)c1 -US20110053931A1,1,COc1cc2c(Cl)ccnc2cc1OCCCN1CCOCC1.Cn1c(Cc2ccccc2)ccc(-c2ccc(O)c(F)c2)c1=O>>COc1cc2c(Oc3ccc(-c4ccc(Cc5ccccc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 -US20080070948A1,1,C1CCC(C2CCNCC2)CC1.O=c1[nH]c2ccccc2n1CCCI>>O=c1[nH]c2ccccc2n1CCCN1CCC(C2CCCCC2)CC1 -US20100016319A1,7,COc1cc([N+](=O)[O-])ccc1C>>COc1cc(N)ccc1C -US20120214803A1,7,COc1cc(NS(=O)(=O)c2ccc(C)cc2[N+](=O)[O-])c2ncccc2c1>>COc1cc(NS(=O)(=O)c2ccc(C)cc2N)c2ncccc2c1 -US20090197897A1,2,Fc1ccc(-c2noc([C@H]3CCCNC3)n2)cc1.O=C(O)C1CCc2cc(F)ccc21>>O=C(C1CCc2cc(F)ccc21)N1CCC[C@H](c2nc(-c3ccc(F)cc3)no2)C1 -US20090137499A1,8,COc1ccc(Cc2ccc(CO)cc2OCc2ccccc2)cc1>>COc1ccc(Cc2ccc(C=O)cc2OCc2ccccc2)cc1 -US20150057273A1,7,CC(C)(C)SC1CC(=O)c2ccccc21>>CC(C)(C)S[C@H]1C[C@@H](O)c2ccccc21 -US05693637,2,COC(=O)CCNC(=O)c1cc(I)ccc1N.O=C(Br)CBr>>COC(=O)CCNC(=O)c1cc(I)ccc1NC(=O)CBr -US08624052B2,2,CCOC(=O)C(N)CSC(C)(C)C.O=C(Cl)c1ccccc1>>CCOC(=O)C(CSC(C)(C)C)NC(=O)c1ccccc1 -US06277991B1,1,ClCc1cccc2ccccc12.O=C1NCN(c2ccccc2)C12CCNCC2>>O=C1NCN(c2ccccc2)C12CCN(Cc1cccc3ccccc13)CC2 -US20140249154A1,4,Cc1ccnc(C(=O)CBr)c1.NC(=S)Nc1ncccn1>>Cc1ccnc(-c2csc(Nc3ncccn3)n2)c1 -US20070254910A1,1,C=O.CN1CCN(c2cccc3nc(CN[C@H]4CCCc5cccnc54)cn23)CC1>>CN1CCN(c2cccc3nc(CN(C)[C@H]4CCCc5cccnc54)cn23)CC1 -US04604401,1,CCNCC1CCNC1.CNn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21>>CCNCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(NC)c3c2F)C1 -US20030130278A1,3,C#CCc1ccc(O[Si](C)(C)C(C)(C)C)cc1.Cn1c(=O)n(Cc2ccc(C(=O)O)cc2)c(=O)c2cc(I)ccc21>>Cn1c(=O)n(Cc2ccc(C(=O)O)cc2)c(=O)c2cc(C#CCc3ccc(O[Si](C)(C)C(C)(C)C)cc3)ccc21 -US06407094B1,3,COc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1I.Cc1cc(F)ccc1B(O)O>>COc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1-c1ccc(F)cc1C -US07572809B2,7,COc1ccc2c(C(=O)OC(C)C)nc(Nc3cc(C)[nH]n3)cc2c1>>COc1ccc2c(CO)nc(Nc3cc(C)[nH]n3)cc2c1 -US20110009402A1,1,CCI.O=c1cc(I)cc[nH]1>>CCn1ccc(I)cc1=O -US20110172230A1,1,N#Cc1ccc(Cl)nc1.OCCC1CCCCC1>>N#Cc1ccc(OCCC2CCCCC2)nc1 -US08278282B2,9,C#C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc2c(Cl)ncnc21.N>>C#C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc2c(N)ncnc21 -US07425631B2,2,CNC1CCOc2cc(CN3CCCCC3)ccc21.O=C(O)CC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1>>CN(C(=O)CC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1)C1CCOc2cc(CN3CCCCC3)ccc21 -US04431653,7,OCCc1ccncc1>>OCCC1CCNCC1 -US05591762,6,CCCCc1nc2c(C)cc(NC(=O)N3CCOCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2c(C)cc(NC(=O)N3CCOCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US07709471B2,1,CN1C(=O)CCN(C2CCCC2)c2nc(Cl)ncc21.CN1[C@H]2CCC[C@@H]1CC(NC(=O)c1cc(F)c(N)cc1F)C2>>CN1C(=O)CCN(C2CCCC2)c2nc(Nc3cc(F)c(C(=O)NC4C[C@@H]5CCC[C@H](C4)N5C)cc3F)ncc21 -US06936602B1,6,CCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3C=O)cc1>>CCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3C=O)cc1 -US04954502,7,COC(=O)Cc1cn(C)c2ccccc12>>Cn1cc(CCO)c2ccccc21 -US05374615,1,CCCCc1nc(Cl)c(C=O)[nH]1.N#Cc1ccccc1-n1cnc2c(CBr)cccc21>>CCCCc1nc(Cl)c(C=O)n1Cc1cccc2c1ncn2-c1ccccc1C#N -US20130338152A1,3,CC1(C)OB(c2cc(OCC3CCCO3)ccc2F)OC1(C)C.Nc1ncnc2c1c(I)cn2[C@@H]1C[C@H](CN2C[C@@H]3C[C@H]2CS3(=O)=O)C1>>Nc1ncnc2c1c(-c1cc(OCC3CCCO3)ccc1F)cn2[C@@H]1C[C@H](CN2C[C@@H]3C[C@H]2CS3(=O)=O)C1 -US08629164B2,4,COC1(OC)C=CC(=O)C=C1NC(=O)OC(C)(C)C.OO>>COC1(OC)C(NC(=O)OC(C)(C)C)=CC(=O)C2OC21 -US06323235B1,1,BrCc1ccccc1.COC(=O)COc1cccc2c(CCNS(=O)(=O)Cc3ccccc3)coc12>>COC(=O)COc1cccc2c(CCN(Cc3ccccc3)S(=O)(=O)Cc3ccccc3)coc12 -US07589206B2,1,CCOC(=O)c1cnc(Cl)c2ccn(CC)c12.Nc1cccc(Cl)c1>>CCOC(=O)c1cnc(Nc2cccc(Cl)c2)c2ccn(CC)c12 -US20090099355A1,2,O=C(O)CCCC(=O)c1ccc(F)cc1.O=C1N[C@@H](c2ccccc2)CO1>>O=C(CCCC(=O)N1C(=O)OC[C@@H]1c1ccccc1)c1ccc(F)cc1 -US20060199817A1,7,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(C3=CCN(C)CC3)nncc2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(C3CCN(C)CC3)nncc2c1 -US06538152B1,2,Cc1ccc(S(=O)(=O)Cl)cc1.NC(=O)c1cc(CCO)ccc1OCc1ccccc1>>Cc1ccc(S(=O)(=O)OCCc2ccc(OCc3ccccc3)c(C(N)=O)c2)cc1 -US20130102599A1,3,CCCC[Sn](CCCC)(CCCC)c1cscn1.CCOC(=O)c1nn(Cc2ccc(Br)nc2)c2ccccc2c1=O>>CCOC(=O)c1nn(Cc2ccc(-c3cscn3)nc2)c2ccccc2c1=O -US07384931B2,6,COC(=O)C[C@@H]1Cc2cc(Br)c3[nH]nc(Cl)c3c2CN(CC(F)(F)F)C1=O>>O=C(O)C[C@@H]1Cc2cc(Br)c3[nH]nc(Cl)c3c2CN(CC(F)(F)F)C1=O -US20070010511A1,1,CC(=O)Nc1cc(CO)ccc1C.COCCCCl>>COCCCN(C(C)=O)c1cc(CO)ccc1C -US20120196874A1,1,CI.CN(C)c1ccc(/C=C/c2c(F)cccc2F)cc1>>C[N+](C)(C)c1ccc(/C=C/c2c(F)cccc2F)cc1 -US06218376B1,1,CCOC(=O)c1coc(CBr)n1.CCc1ccc2c(c1)C=Cc1oc(C)nc1C2c1c[nH]c(=O)[nH]c1=O>>CCOC(=O)c1coc(Cn2cc(C3c4ccc(CC)cc4C=Cc4oc(C)nc43)c(=O)[nH]c2=O)n1 -US20120010185A1,1,C=O.O=c1cc(OCc2ccccc2)ccn1CCc1ccc2c(c1)CCNC2>>CN1CCc2cc(CCn3ccc(OCc4ccccc4)cc3=O)ccc2C1 -US06552054B1,2,Nc1ccc(CN2C(=O)CNC2=O)cc1.O=C(O)c1cc(=O)c2ccccc2o1>>O=C(Nc1ccc(CN2C(=O)CNC2=O)cc1)c1cc(=O)c2ccccc2o1 -US20140228405A1,1,CN1CCC(=O)CC1.N[C@@H]1C[C@H]1c1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1>>CN1CCC(N[C@@H]2C[C@H]2c2ccc(NC(=O)c3cccc(C(F)(F)F)c3)cc2)CC1 -US20100160369A1,7,COC(=O)C1(C)COC(=O)N1>>CC1(CO)COC(=O)N1 -US20100331315A1,2,CN1CCNCC1.O=C1NC(=S)SC1=Cc1ccc(-c2ccc(C(=O)O)cc2)o1>>CN1CCN(C(=O)c2ccc(-c3ccc(C=C4SC(=S)NC4=O)o3)cc2)CC1 -US20120328569A1,2,COC(=O)c1c(-c2ccc(F)cc2)oc2cc(N)c(Br)cc12.O=S(=O)(Cl)c1ccccc1>>COC(=O)c1c(-c2ccc(F)cc2)oc2cc(NS(=O)(=O)c3ccccc3)c(Br)cc12 -US08003648B2,7,Cc1oc(-c2ccc(Cl)cc2)cc1C(=O)O>>Cc1oc(-c2ccc(Cl)cc2)cc1CO -US05877202,1,BrCc1ccccc1.COC(=O)c1c[nH]c2ccc(Cl)cc12>>COC(=O)c1cn(Cc2ccccc2)c2ccc(Cl)cc12 -US20130317065A1,9,N.O=C(OCc1ccccc1)c1cccc(Cc2c(-c3ccccc3)[nH]c3cc(C4CC4)ccc23)n1>>NC(=O)c1cccc(Cc2c(-c3ccccc3)[nH]c3cc(C4CC4)ccc23)n1 -US04032537,1,C=CCBr.O=c1ccsc2c1[nH]c1ccccc12>>C=CCn1c2ccccc2c2sccc(=O)c21 -US20130324579A1,1,Cc1n[nH]c(C)c1[N+](=O)[O-].OCCBr>>Cc1nn(CCO)c(C)c1[N+](=O)[O-] -US07598264B2,6,CCc1c2c(c(OC)c(=O)n1C)C(=O)N(Cc1ccc(F)c(Cl)c1)CC2>>CCc1c2c(c(O)c(=O)n1C)C(=O)N(Cc1ccc(F)c(Cl)c1)CC2 -US20070197577A1,6,COC[C@H](Cc1ccccc1)NC(=O)[C@H](NC(=O)OC(C)(C)C)c1ccc(-c2ccccc2)cc1>>COC[C@H](Cc1ccccc1)NC(=O)[C@H](N)c1ccc(-c2ccccc2)cc1 -US05578612,1,CCI.CCS(=O)(=O)CCc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1>>CCN1CCC[C@@H]1Cc1c[nH]c2ccc(CCS(=O)(=O)CC)cc12 -US20140343086A1,1,O=C(Nc1ccc(SC(F)(F)F)nc1)c1cnc(Cl)c(Br)c1.O[C@@H]1CCNC1>>O=C(Nc1ccc(SC(F)(F)F)nc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1 -US20050192325A1,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Nc1cc(F)c(C=O)c(F)c1>>CCOC(=O)/C=C/c1c(F)cc(N)cc1F -US08501732B2,1,COC(=O)c1c(CBr)c(=O)c2ccc(Cl)cc2n1-c1ccccc1.Nc1nccc2ccccc12>>COC(=O)c1c(CNc2nccc3ccccc23)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 -US07390835B2,9,O=C(CBr)c1ccc(-c2ccccc2)cc1.[C-]#N>>N#CCC(=O)c1ccc(-c2ccccc2)cc1 -US08168658B2,2,CC(=O)NCC(C(=O)O)c1ccc(C(=O)OC(C)(C)C)cc1.Nc1ccccc1>>CC(=O)NCC(C(=O)Nc1ccccc1)c1ccc(C(=O)OC(C)(C)C)cc1 -US06399619B1,6,C[SiH](C)OC([C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccccc1)C(C)(C)C>>C[SiH](C)OC([C@H]1CNC[C@@H]1c1ccccc1)C(C)(C)C -US20100204196A1,7,COc1cc(N2CCC(N3CC[C@H](F)C3)CC2)ccc1[N+](=O)[O-]>>COc1cc(N2CCC(N3CC[C@H](F)C3)CC2)ccc1N -US20150099771A1,1,[N-]=[N+]=N[C@@H]1c2cccnc2C(=O)CC[C@H]1c1cccc(F)c1F.[NH4+]>>[N-]=[N+]=N[C@@H]1c2cccnc2[C@H](N)CC[C@H]1c1cccc(F)c1F -US20120316147A1,2,CNC(=O)[C@@H](N)CC(C)(C)C.O=C(O)c1cccc(-c2cccc(Cl)c2)n1>>CNC(=O)[C@H](CC(C)(C)C)NC(=O)c1cccc(-c2cccc(Cl)c2)n1 -US20090318690A1,1,CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(O)ccc23)CC1.CS(=O)(=O)OCc1ccc(C#N)s1>>CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(OCc4ccc(C#N)s4)ccc23)CC1 -US20090312310A1,2,CC(C)C1=C(C(=O)O)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21.CC(C)NCC(=O)OC(C)(C)C>>CC(C)C1=C(C(=O)N(CC(=O)OC(C)(C)C)C(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21 -US05602137,1,N#Cc1cccn1-c1ccc(CBr)cc1.O=C1NC(=O)c2ccccc21>>N#Cc1cccn1-c1ccc(CN2C(=O)c3ccccc3C2=O)cc1 -US06593322B1,1,NC(=O)CBr.Oc1ccc2c(c1)CCN(c1ccc(F)cc1)C2Cc1ccc(OCCC2CCCCN2)cc1>>NC(=O)COc1ccc2c(c1)CCN(c1ccc(F)cc1)C2Cc1ccc(OCCC2CCCCN2)cc1 -US20150191461A1,9,COC(=O)C(O)Cn1cc(I)cn1.N>>NC(=O)C(O)Cn1cc(I)cn1 -US20130316938A1,3,CC(=O)CCc1ccc(O)cc1.c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CC(=Cc1ccccc1)CCc1ccc(O)cc1 -US05478845,7,O=C(O)C(CN1CCC(c2noc3cc(F)ccc23)CC1)c1ccccc1>>OCC(CN1CCC(c2noc3cc(F)ccc23)CC1)c1ccccc1 -US05326769,2,O=C(O)c1cc(-c2ccccc2)c(=O)n2c1-c1cc(Cl)ccc1CC2.O[C@H]1CCNC1>>O=C(c1cc(-c2ccccc2)c(=O)n2c1-c1cc(Cl)ccc1CC2)N1CC[C@H](O)C1 -US07078414B2,1,CCOC(=O)c1cc[nH]c1C.Clc1ccnc2ccccc12>>CCOC(=O)c1ccn(-c2ccnc3ccccc23)c1C -US20040110786A1,1,O=C(NCc1ccc(Cl)cc1)C(=CNCCN1CCOCC1)C(=O)c1cc(CN2CCOCC2)sc1Cl>>O=C(NCc1ccc(Cl)cc1)c1cn(CCN2CCOCC2)c2sc(CN3CCOCC3)cc2c1=O -US07435815B2,2,CCNCc1ncc[nH]1.CN(C)c1cccc(N(CC(=O)O)S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1>>CCN(Cc1ncc[nH]1)C(=O)CN(c1cccc(N(C)C)c1)S(=O)(=O)c1ccc(C(C)(C)C)cc1 -US20140213657A1,1,N[C@@H]1C[C@H]1c1ccc(OCc2cccc(Br)c2)cc1.O=CCC1CCCCC1>>Brc1cccc(COc2ccc([C@@H]3C[C@H]3NCCC3CCCCC3)cc2)c1 -US20150252047A1,1,Clc1ncnc2[nH]c(Br)cc12.Nc1cc2cn[nH]c2cc1F>>Fc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c(Br)cc12 -US04730006,1,BrCc1ccccc1.OCCCO>>OCCCOCc1ccccc1 -US20030018197A1,7,Cc1nn(-c2ccccc2)c(Sc2cc(Cl)cc(Cl)c2)c1C=Cc1ccccc1>>Cc1nn(-c2ccccc2)c(Sc2cc(Cl)cc(Cl)c2)c1CCc1ccccc1 -US06025372,2,CC(C)(C)OC(=O)NCc1ccnc(CN)c1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)NCc1ccnc(CNC(=O)OCc2ccccc2)c1 -US08450310B2,2,CCN.CCOC(=O)c1cc(-c2cc(Br)c(OCc3ccccc3)cc2OCc2ccccc2)on1>>CCNC(=O)c1cc(-c2cc(Br)c(OCc3ccccc3)cc2OCc2ccccc2)on1 -US05728686,1,CCOP(=O)(CCCCCl)OCC.Cn1c(=O)c2[nH]cnc2n(C)c1=O>>CCOP(=O)(CCCCn1cnc2c1c(=O)n(C)c(=O)n2C)OCC -US20060276464A1,1,CC(C)c1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)NC1CCOCC1.CN1CCNCC1>>CC(C)c1ccc(S(=O)(=O)c2ccc(N3CCN(C)CC3)cc2)cc1S(=O)(=O)NC1CCOCC1 -US20150133424A1,7,O=C(c1cccc([N+](=O)[O-])c1)N1CCC(O)CC1>>Nc1cccc(C(=O)N2CCC(O)CC2)c1 -US20100120793A1,1,CCOC(=O)C1(CI)CCN(C(=O)c2ccccc2OCC)C1.Oc1cnc(-c2ccc(Cl)cc2)nc1>>CCOC(=O)C1(COc2cnc(-c3ccc(Cl)cc3)nc2)CCN(C(=O)c2ccccc2OCC)C1 -US06169107A,1,CC(C)(C)OC(=O)NCCCI.CCOC(=O)c1cc2c(C(F)(F)F)cc(O)cc2n1C>>CCOC(=O)c1cc2c(C(F)(F)F)cc(OCCCNC(=O)OC(C)(C)C)cc2n1C -US20130040978A1,1,O=C(O)c1ccc(C2=NOC3(CCNCC3)C2)cc1.O=Cc1ccc(Cl)c(OC(F)(F)F)c1>>O=C(O)c1ccc(C2=NOC3(CCN(Cc4ccc(Cl)c(OC(F)(F)F)c4)CC3)C2)cc1 -US20110263647A1,2,CC(C)(C)OC(=O)NCC(=O)O.C[C@H](O)/C=C/c1ccc(C(F)(F)F)cc1>>C[C@@H](/C=C/c1ccc(C(F)(F)F)cc1)OC(=O)CNC(=O)OC(C)(C)C -US20040133008A1,2,CC(C)(C)OC(=O)N1CCc2cc(N)ccc21.Cc1ccc(C(=O)O)c(Cl)n1>>Cc1ccc(C(=O)Nc2ccc3c(c2)CCN3C(=O)OC(C)(C)C)c(Cl)n1 -US20110230500A1,1,N[C@@H](CO)c1ccccc1.Nc1cc(F)ccc1[N+](=O)[O-]>>Nc1cc(OC[C@H](N)c2ccccc2)ccc1[N+](=O)[O-] -US09095590B2,2,CC(C)(C)OC(=O)Nc1ccc(O)cc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)Nc1ccc(OS(C)(=O)=O)cc1 -US06825191B2,6,COc1ccc2c(c1)CN(C(=O)c1ccc(Cl)cc1)CC(=O)N2Cc1ccc(C(=O)N2CC=CC2)cc1>>O=C(c1ccc(CN2C(=O)CN(C(=O)c3ccc(Cl)cc3)Cc3cc(O)ccc32)cc1)N1CC=CC1 -US20110160202A1,1,COC[C@@H]1CCCN1.Clc1nccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1>>COC[C@@H]1CCCN1c1nccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1 -US08044068B2,6,CC(C)(C)OC(=O)N1CCN(c2nc(N[C@H]3CCN(C(=O)Cc4ccccc4)C3)nc3ccccc23)CC1>>O=C(Cc1ccccc1)N1CC[C@H](Nc2nc(N3CCNCC3)c3ccccc3n2)C1 -US05580883,6,CN(C)c1ccc(OCC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CN(C)c1ccc(OCC2CCNCC2)cc1 -US20070244125A1,1,O=C(c1ccc2[nH]c(C(=O)N3CCS(=O)(=O)CC3)cc2c1)N1CCN(C2CCC2)CC1.OB(O)c1cccc(Cl)c1>>O=C(c1ccc2c(c1)cc(C(=O)N1CCS(=O)(=O)CC1)n2-c1cccc(Cl)c1)N1CCN(C2CCC2)CC1 -US20080051398A1,1,CI.COc1ccc(OC)c(Nc2nc(Cl)nc3ccccc23)c1>>COc1ccc(OC)c(N(C)c2nc(Cl)nc3ccccc23)c1 -US20090253676A1,6,C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2F)cc(C(=O)Nc2nccs2)c1>>C[C@@H](CO)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2F)cc(C(=O)Nc2nccs2)c1 -US06737425B1,1,CC(=O)c1cc(F)ccc1O.CCOC(=O)CI>>CCOC(=O)COc1ccc(F)cc1C(C)=O -US05672615,1,CCOC(=O)CNS(=O)(=O)c1ccc(OC)cc1.ClCc1ccc2ccccc2n1>>CCOC(=O)CN(Cc1ccc2ccccc2n1)S(=O)(=O)c1ccc(OC)cc1 -US20110190247A1,7,O=C1CCOc2ccc(Br)cc21>>OC1CCOc2ccc(Br)cc21 -US03958974,2,Nc1ccc(Cl)c(Cl)c1.O=C(Cl)CCCl>>O=C(CCCl)Nc1ccc(Cl)c(Cl)c1 -US05858924,2,COc1cnc(OC)n2nc(N)nc12.COc1nccc(C(F)(F)F)c1S(=O)(=O)Cl>>COc1nccc(C(F)(F)F)c1S(=O)(=O)Nc1nc2c(OC)cnc(OC)n2n1 -US04636563,1,BrCCCc1ccccn1.Clc1ccc2[nH]c3c(c2c1)CNCC3>>Clc1ccc2[nH]c3c(c2c1)CN(CCCc1ccccn1)CC3 -US20080317671A1,6,COCCN(Cc1nc(C(=O)N2CCN(C(C)C)CC2)co1)C(=O)OC(C)(C)C>>COCCNCc1nc(C(=O)N2CCN(C(C)C)CC2)co1 -US20150018422A1,1,CCOC(=O)CC(c1cccc(CO)c1)C1CC1.COc1ccc(F)c(-c2ccc(O)c(C(CC(C)(C)C)OC)c2)c1>>CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)cc2C(CC(C)(C)C)OC)c1)C1CC1 -US20090318448A1,3,Cc1c(B2OC(C)(C)C(C)(C)O2)cccc1-n1cnc2cc(C(C)(C)C)ccc2c1=O.Cn1nc(Cl)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O>>Cc1c(-c2cc(Nc3ccc(C(=O)N4CCOCC4)cn3)c(=O)n(C)n2)cccc1-n1cnc2cc(C(C)(C)C)ccc2c1=O -US07776890B2,1,Fc1cccc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc(CCl)cc23)c1.O[C@H]1CCOC1>>Fc1cccc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc(CO[C@H]4CCOC4)cc23)c1 -US20060025414A1,6,CC(C)(C)OC(=O)N1CCOCC1c1nc(-c2cccc(Cl)c2)no1>>Clc1cccc(-c2noc(C3COCCN3)n2)c1 -US20100286173A1,2,CCCCOC(=O)Cl.Cc1ccc(C(=NOCc2nccc(N)n2)c2nnnn2C)cc1C(F)(F)F>>CCCCOC(=O)Nc1ccnc(CON=C(c2ccc(C)c(C(F)(F)F)c2)c2nnnn2C)n1 -US20120190635A1,6,CC(=O)OC1C(OC2CCCCC2)OC(C)CC1N(C)C>>CC1CC(N(C)C)C(O)C(OC2CCCCC2)O1 -US05344843,1,CCCc1c(OCCCBr)ccc(C(=O)OC)c1O.CCOC(=O)C(=O)c1ccc(O)cc1>>CCCc1c(OCCCOc2ccc(C(=O)C(=O)OCC)cc2)ccc(C(=O)OC)c1O -US20090318436A1,3,CCCC[Sn](CCCC)(CCCC)c1cc(C)no1.Fc1ccc(Br)cn1>>Cc1cc(-c2ccc(F)nc2)on1 -US20110124686A1,2,COc1ccc(Cl)c(CN(Cc2cccc(CN3C(C(=O)O)CCS3(=O)=O)c2)[C@H](CN(C)C)CC(C)(C)C)c1F.C[C@H]1[C@H](N)C[C@@H]2C[C@H]1C2(C)C>>COc1ccc(Cl)c(CN(Cc2cccc(CN3C(C(=O)N[C@@H]4C[C@@H]5C[C@H]([C@H]4C)C5(C)C)CCS3(=O)=O)c2)[C@H](CN(C)C)CC(C)(C)C)c1F -US20060234997A1,1,BrCCCBr.CC1(C)CCC(=O)Nc2cc(O)ccc21>>CC1(C)CCC(=O)Nc2cc(OCCCBr)ccc21 -US20120245161A1,6,COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)OC(C)(C)C)ccc3OCC(=O)OC)CC2)c2cccc(C)c21>>COCCn1cc(C(=O)N2CCC(c3cc(CN)ccc3OCC(=O)OC)CC2)c2cccc(C)c21 -US08993595B2,6,COc1ccc(COc2cc(-c3nc(C(C)C)cs3)nc3c(C)cc(OC)cc23)cc1>>COc1cc(C)c2nc(-c3nc(C(C)C)cs3)cc(O)c2c1 -US05223539,2,CC(C)NC1CCCCC1.O=C(Cl)c1ccc(Br)c(Cl)c1>>CC(C)N(C(=O)c1ccc(Br)c(Cl)c1)C1CCCCC1 -US20100093703A1,8,CSc1ccnc(-n2ccc3cc(N(CC(=O)OC(C)(C)C)S(=O)(=O)c4cc(Cl)cc(Cl)c4)ccc32)c1.OO>>CS(=O)c1ccnc(-n2ccc3cc(N(CC(=O)OC(C)(C)C)S(=O)(=O)c4cc(Cl)cc(Cl)c4)ccc32)c1 -US20120270865A2,6,COC(=O)c1ccc(NC(c2oc3ccc(OCC4CC4)cc3c2C)C(C)C)cn1>>Cc1c(C(Nc2ccc(C(=O)O)nc2)C(C)C)oc2ccc(OCC3CC3)cc12 -US20030158210A1,9,COc1ccc(N2CCN(c3ccc(-n4cnn(C(C)C(C)OS(C)(=O)=O)c4=O)cc3)CC2)cc1>>COc1ccc(N2CCN(c3ccc(-n4cnn(C(C)C(C)O)c4=O)cc3)CC2)cc1 -US07393865B2,9,CN(C)CCc1sc2ccccc2c1C(C)(O)c1cncs1>>CC(c1cncs1)c1c(CCN(C)C)sc2ccccc12 -US06489324B2,2,CS(=O)(=O)Cl.Oc1ccc(-c2cccs2)cc1>>CS(=O)(=O)Oc1ccc(-c2cccs2)cc1 -US06627651B1,6,CCCOCc1ccccc1Oc1ccc2c(c1)C=C(C(=O)OC)CCS2(=O)=O>>CCCOCc1ccccc1Oc1ccc2c(c1)C=C(C(=O)O)CCS2(=O)=O -US04593104,1,Cc1cccc(C)c1N(CCl)C(=O)CCl.c1nc[nH]n1>>Cc1cccc(C)c1N(Cn1cncn1)C(=O)CCl -US09156827B2,6,COc1ccc2c(c1/C=C\CCN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O>>COc1ccc2c(c1/C=C\CCN1CCNCC1)O/C(=C\c1n[nH]c3ccccc13)C2=O -US09040522B2,2,CN1CCNCC12CC2.Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)O)cn2)c1O>>Cc1cc(C#N)ccc1-c1cnn(-c2ccc(C(=O)N3CCN(C)C4(CC4)C3)cn2)c1O -US05093328,6,CNC(=O)[C@@H]1C[C@H](SC(C)=O)CN1C>>CNC(=O)[C@@H]1C[C@H](S)CN1C -US20100144787A1,6,CCc1nc2c(Cl)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(C(=O)C(C)(C)C)cc1>>CCc1nc2c(Cl)ccc(OCC(=O)O)c2c(OC(F)F)c1Cc1ccc(C(=O)C(C)(C)C)cc1 -US20030083341A1,1,CCOC(=O)c1cc(Br)c(O)c(I)c1.OCCO>>CCOC(=O)c1cc(Br)c(OCCO)c(I)c1 -US20100256156A1,1,CSCCCO.Oc1ccc(Br)cc1>>CSCCCOc1ccc(Br)cc1 -US20060076296A1,1,CNC.[SiH3]CCCCCCCCCCCCCCCCCCC=CCCl>>CN(C)CC=CCCCCCCCCCCCCCCCCCC[SiH3] -US08604015B2,1,BrCCOc1ccccc1.O=C(N[C@H]1CN2CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1>>O=C(N[C@H]1C[N+]2(CCOc3ccccc3)CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1 -US20120316147A1,2,NC(=O)[C@@H](N)c1ccc(Cl)cc1.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>NC(=O)[C@@H](NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)c1ccc(Cl)cc1 -US20060035956A1,1,CC(C)(C)[Si](C)(C)Oc1cccc2cc[nH]c12.CCOC(=O)CBr>>CCOC(=O)Cn1ccc2cccc(O[Si](C)(C)C(C)(C)C)c21 -US20120252789A1,6,CC(C)(C)OC(=O)NC1CCN(c2ccnc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)n2)CC1>>CC1(C)CCC(C)(C)c2cc(-c3nccc(N4CCC(N)CC4)n3)ccc21 -US20120058988A1,2,CN(C)CCCC(=O)O.COc1cccc(-c2cc(C(N)=O)c3[nH]c4cc(N)ccc4c3c2)c1>>COc1cccc(-c2cc(C(N)=O)c3[nH]c4cc(NC(=O)CCCN(C)C)ccc4c3c2)c1 -US07115741B2,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1ncnc2nc[nH]c12>>CC(C)(C)OC(=O)N1CCN(c2ncnc3nc[nH]c23)CC1 -US20090042896A1,6,C[C@H](Oc1ccc(Cl)cn1)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)c(F)c1>>C[C@H](Oc1ccc(Cl)cn1)[C@H]1CNC[C@@H]1c1ccc(Cl)c(F)c1 -US04264622,1,CCCN(CCC)C1CCc2c[nH]cc2C1.CI>>CCCN(CCC)C1CCc2cn(C)cc2C1 -US08263615B2,9,COc1ccc(C2(O)c3cncn3CCC2(C)C)cc1>>COc1ccc(C2c3cncn3CCC2(C)C)cc1 -US20090247577A1,2,CC(C)(C)OC(=O)CCCNC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CC1CCCCC1.O=C1CC(C(=O)O)c2ccccc2N1>>CC(C)(C)OC(=O)CCCN(C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CC1CCCCC1)C(=O)C1CC(=O)Nc2ccccc21 -US06787536B2,5,Brc1ccc(N2CCNCC2)cc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(c2ccc(Br)cc2)CC1 -US20140171429A1,3,COc1cc(N2CCN(C)CC2)ccc1Nc1nc(Cl)cc2cc[nH]c(=O)c12.Clc1cccc(Cl)c1C[Zn+]>>COc1cc(N2CCN(C)CC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)cc2cc[nH]c(=O)c12 -US20050026836A1,1,CCOC(CBr)OCC.Oc1cccc(Br)c1>>CCOC(COc1cccc(Br)c1)OCC -US05849735,2,O=C(Cl)c1ccc(NC(=O)c2ccccc2-c2ccccc2)nc1.c1ccc2c(c1)CNc1cccnc1O2>>O=C(Nc1ccc(C(=O)N2Cc3ccccc3Oc3ncccc32)cn1)c1ccccc1-c1ccccc1 -US20090275573A1,6,CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1CNc1cccc(Cl)c1>>FC1(F)CN[C@H](CNc2cccc(Cl)c2)C1 -US20100076001A1,6,COCOc1cnccc1-c1cccc2cc(-c3nc(Cl)ncc3F)sc12>>Oc1cnccc1-c1cccc2cc(-c3nc(Cl)ncc3F)sc12 -US06489344B1,2,CC(=O)c1ccc(C(=O)O)cc1.COc1cccc(CN)c1>>COc1cccc(CNC(=O)c2ccc(C(C)=O)cc2)c1 -US05665749,10,Cc1ccc2c(c1)S(=O)(=O)N(C)C2=O.O=C1CCC(=O)N1Br>>CN1C(=O)c2ccc(CBr)cc2S1(=O)=O -US20050119326A1,1,BrCCCBr.COC(=O)Cc1ccc(O)cc1>>COC(=O)Cc1ccc(OCCCBr)cc1 -US20070185097A1,7,O=[N+]([O-])c1ccc(OCCN2CCCC2)c(Cl)c1>>Nc1ccc(OCCN2CCCC2)c(Cl)c1 -US20100145042A1,3,C=O.CC(=O)c1ccc(Cl)cc1.CNC>>CN(C)CCC(=O)c1ccc(Cl)cc1 -US05908858,9,CCOC(=O)C(CC(=O)c1ccc(OC)cc1)(Cc1ccc(OC)c(OC2CCCC2)c1)C(=O)OCC>>CCOC(=O)C(CC(=O)c1ccc(OC)cc1)Cc1ccc(OC)c(OC2CCCC2)c1 -US07750020B2,2,CN1CCN(S(=O)(=O)c2ccc(C(CC3CCCC3)C(=O)O)cc2)CC1.COc1ccc2nc(N)sc2n1>>COc1ccc2nc(NC(=O)C(CC3CCCC3)c3ccc(S(=O)(=O)N4CCN(C)CC4)cc3)sc2n1 -US20060135517A1,1,Cc1cc(Br)c2nc(-c3cccc(C)n3)c(-c3ccnc(O)n3)n2c1.NCCc1ccccn1>>Cc1cc(NCCc2ccccn2)c2nc(-c3cccc(C)n3)c(-c3ccnc(O)n3)n2c1 -US06825230B2,2,CC(=O)Cl.O=C1CCC(c2ccc(O)cc2)CC1>>CC(=O)Oc1ccc(C2CCC(=O)CC2)cc1 -US20150031685A1,6,Cc1nc(-c2cccc([C@@H](CN3CC[C@H](O)C3)N(C)C(=O)OCc3ccccc3)c2)no1>>CN[C@H](CN1CC[C@H](O)C1)c1cccc(-c2noc(C)n2)c1 -US08586208B2,1,COC(=O)/C=C/c1ccc(O)cc1.FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCI>>COC(=O)/C=C/c1ccc(OCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1 -US08063061B2,4,CC(C)(C)C(=O)OCC(N)=S.Cn1c(=O)c(-c2ccc(F)cc2)cc2c3cc(C(=O)CBr)ccc3n(C)c21>>Cn1c(=O)c(-c2ccc(F)cc2)cc2c3cc(-c4csc(COC(=O)C(C)(C)C)n4)ccc3n(C)c21 -US08273740B2,6,CC(C)(C)OC(=O)Cn1c(SCc2ccccc2)nc2cc([N+](=O)[O-])ccc21>>O=C(O)Cn1c(SCc2ccccc2)nc2cc([N+](=O)[O-])ccc21 -US20100190764A1,2,CCOC(=O)C1CCCNC1.O=C(Cl)OCc1ccccc1>>CCOC(=O)C1CCCN(C(=O)OCc2ccccc2)C1 -US20100280268A1,1,COC(=O)c1cc(O)ccc1NS(=O)(=O)c1ccc(C)cc1.N#Cc1cc(F)ccc1[N+](=O)[O-]>>COC(=O)c1cc(Oc2ccc([N+](=O)[O-])c(C#N)c2)ccc1NS(=O)(=O)c1ccc(C)cc1 -US20090082434A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1Cc2c(F)c(F)cc(Br)c2O1>>Cc1ccc(S(=O)(=O)OCC2Cc3c(F)c(F)cc(Br)c3O2)cc1 -US06919331B2,1,CC(C)(C)OC(=O)Cn1c(=O)[nH]c2ccccc21.CC(C)CCn1c(CCl)nc2cc(C#N)ccc21>>CC(C)CCn1c(Cn2c(=O)n(CC(=O)OC(C)(C)C)c3ccccc32)nc2cc(C#N)ccc21 -US20130274244A1,1,CC(C)(C)OC(=O)N1CCN(CCO)CC1.Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(F)ccn45)cccc32)n1>>Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C(=O)OC(C)(C)C)CC6)ccn45)cccc32)n1 -US05424333,1,Cc1ccc(C(=O)NNC(C)(C)C)cc1.O=C(Cl)c1cc(Cl)sc1Cl>>Cc1ccc(C(=O)NN(C(=O)c2cc(Cl)sc2Cl)C(C)(C)C)cc1 -US05034417,7,CNC(=O)c1ccc([N+](=O)[O-])c(Sc2ccc(F)cc2F)c1>>CNC(=O)c1ccc(N)c(Sc2ccc(F)cc2F)c1 -US20150126490A1,3,CC(C)(C)OC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1F.Nc1nccnc1Cl>>CC(C)(C)OC(=O)c1ccc(-c2nccnc2N)cc1F -US20090054405A1,3,CC(=O)Nc1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2s1.O=S(=O)(c1ccc(F)cc1)c1cccc(Cl)n1>>CC(=O)Nc1nc2ccc(-c3cccc(S(=O)(=O)c4ccc(F)cc4)n3)cc2s1 -US07342012B2,3,CN(C)C=O.N#Cc1ccc(CC23CCCN2C(=O)N(c2cc(Cl)cc(-n4cccc4)c2)C3=O)cc1>>N#Cc1ccc(CC23CCCN2C(=O)N(c2cc(Cl)cc(-n4cccc4C=O)c2)C3=O)cc1 -US20110281874A1,2,CN(C)CCN.Cc1csc(Nc2ncc(SC(C)c3ccccn3)cc2Oc2cc(C(=O)O)ccc2Cl)n1>>Cc1csc(Nc2ncc(SC(C)c3ccccn3)cc2Oc2cc(C(=O)NCCN(C)C)ccc2Cl)n1 -US07915274B2,2,CC(C)(C)OC(=O)N1CCC(C#N)(CO)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(C#N)(COS(C)(=O)=O)CC1 -US06359134B1,6,Cc1nc(-c2ccc(NC(=O)OC(C)(C)C)nc2)sc1C(=O)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1>>Cc1nc(-c2ccc(N)nc2)sc1C(=O)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1 -US20010031781A1,4,CC(C)(C)c1cc(C(=O)CBr)n(Cc2ccccc2)n1.COC(=S)c1cc(C(N)=S)c(C)s1>>COC(=S)c1cc(-c2nc(-c3cc(C(C)(C)C)nn3Cc3ccccc3)cs2)c(C)s1 -US06090805,6,COC(=O)Cc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1OCC(F)(F)F>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(CC(=O)O)c(OCC(F)(F)F)c2)CC1 -US20140364601A1,2,CC(C)(C)OC(=O)N1CCC2(CC1)CNCCO2.CC(C)c1nc(C(=O)O)cs1>>CC(C)c1nc(C(=O)N2CCOC3(CCN(C(=O)OC(C)(C)C)CC3)C2)cs1 -US20130261128A1,1,BrCc1ccccc1.O=C(O)c1cnc(-c2ccc(Br)nc2)[nH]1>>O=C(OCc1ccccc1)c1cnc(-c2ccc(Br)nc2)[nH]1 -US20060135483A1,1,CCOP(=O)(OCC)C(F)(F)c1ccc(CBr)cc1Br.COC(=O)c1ccccc1-c1ccc(-c2cnc(Nc3ccc(Cl)c(Cl)c3)o2)cc1>>CCOP(=O)(OCC)C(F)(F)c1ccc(CN(c2ccc(Cl)c(Cl)c2)c2ncc(-c3ccc(-c4ccccc4C(=O)OC)cc3)o2)cc1Br -US20140088076A1,6,COC(=O)c1ccc(CN2CCN(C)CC2)c(Cl)c1>>CN1CCN(Cc2ccc(C(=O)O)cc2Cl)CC1 -US20110257151A1,2,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(N2C(=O)OC[C@H]2Cc2ccccc2)c1.NS(=O)(=O)C1CC1>>CC1(C)Cc2cc(C(=O)NS(=O)(=O)C3CC3)ccc2NC1c1cccc(N2C(=O)OC[C@H]2Cc2ccccc2)c1 -US20080287455A1,2,CCSc1ccc(S(C)(=O)=O)cc1C(=O)O.CS(=O)(=O)c1ccc(N2CCNCC2)c(F)c1>>CCSc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ccc(S(C)(=O)=O)cc2F)CC1 -US06518273B1,2,O=C(CCc1c(-c2ccc(Cl)cc2)[nH]c2ccc(Cl)cc12)N1CCNCC1.O=C(Cl)c1ccccc1>>O=C(CCc1c(-c2ccc(Cl)cc2)[nH]c2ccc(Cl)cc12)N1CCN(C(=O)c2ccccc2)CC1 -US20140309226A1,6,CC(c1cc(F)c(Br)cc1F)N(CCNC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CC(c1cc(F)c(Br)cc1F)N(CCN)C(=O)OCc1ccccc1 -US04421919,2,O=C(Cl)Cl.O=C1CCNc2ccc(F)cc21>>O=C1CCN(C(=O)Cl)c2ccc(F)cc21 -US08084448B2,9,COC(=O)C(Br)c1ccccc1I.[N-]=[N+]=[N-]>>COC(=O)C(N=[N+]=[N-])c1ccccc1I -US20130172335A1,3,CC(c1ccc(Br)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.O=C(O)c1ccc(B(O)O)cc1>>CC(c1ccc(-c2ccc(C(=O)O)cc2)cc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F -US20130338142A1,7,O=[N+]([O-])c1ccc(N2CCOC(CCO)C2)cc1>>Nc1ccc(N2CCOC(CCO)C2)cc1 -US08853408B2,6,CC(C)(C)OC(=O)CN1CCC(CN[C@@H]2C[C@H]2c2ccccc2)CC1>>O=C(O)CN1CCC(CN[C@@H]2C[C@H]2c2ccccc2)CC1 -US20120142714A1,6,CCOc1ccc(C#C[Si](C)(C)C)nc1>>C#Cc1ccc(OCC)cn1 -US05241060,9,N.O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1Br>>Nc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O -US20150094328A1,3,CCCC[Sn](CCCC)(CCCC)c1cn(C)cn1.O=C(N[C@H]1CCCC[C@@H]1O)c1cn(Cc2ccc(Br)cc2)c2cccnc12>>Cn1cnc(-c2ccc(Cn3cc(C(=O)N[C@H]4CCCC[C@@H]4O)c4ncccc43)cc2)c1 -US20030120069A1,6,COC(=O)c1cc(OC)c(C)c(OC)c1[N+](=O)[O-]>>COc1cc(C(=O)O)c([N+](=O)[O-])c(OC)c1C -US06291683B1,1,OCCCl.Oc1cccc2[nH]ccc12>>ClCCOc1cccc2[nH]ccc12 -US20100120785A1,1,Clc1nccnc1N1CCNCC1.O=Cc1cnn(CCO)c1>>OCCn1cc(CN2CCN(c3nccnc3Cl)CC2)cn1 -US06569504B1,6,CCCCCCCC/C=C\CCCCCCCCOc1ccc(-c2ccc(C(=O)OC)cc2)cc1>>CCCCCCCC/C=C\CCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 -US20130310384A1,1,COC(=O)c1ccc(CBr)cc1.O=S(=O)(N[C@H](CO)c1ccccc1)c1ccc(Cl)cc1>>COC(=O)c1ccc(CN([C@H](CO)c2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1 -US20070203159A1,3,COc1ccc(Cn2cnc3c(-c4ccco4)nc(Cl)nc32)cc1.[Zn+]C1CC1>>COc1ccc(Cn2cnc3c(-c4ccco4)nc(C4CC4)nc32)cc1 -US20030166932A1,7,COc1ccc(C(=O)CCC(=O)O)cc1C>>COc1ccc(CCCC(=O)O)cc1C -US20020068734A1,2,COc1cc2ncnc(N3CCNCC3)c2cc1OC.O=C=Nc1ccccc1>>COc1cc2ncnc(N3CCN(C(=O)Nc4ccccc4)CC3)c2cc1OC -US20040048916A1,7,CC(C)CN1C(=O)c2c(F)ccc(F)c2C1=O>>CC(C)CN1C(=O)c2c(F)ccc(F)c2C1O -US20150225404A1,1,Cc1ccnc(CO)c1.Clc1cc(-c2cccnc2)c2c(n1)CCCC2>>Cc1ccnc(COc2cc(-c3cccnc3)c3c(n2)CCCC3)c1 -US08691822B2,1,C=O.CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCC4CNCCO4)c4c3OCC4)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NCC4CN(C)CCO4)c4c3OCC4)nc2N1C1CCCC1 -US20150152108A1,1,NC(=O)CCl.O=C(Nc1cccc(C2CCNC2)c1)N1c2nc(-c3cccc(C(F)(F)F)c3)ccc2N2CC[C@H]1C2>>NC(=O)CN1CCC(c2cccc(NC(=O)N3c4nc(-c5cccc(C(F)(F)F)c5)ccc4N4CC[C@H]3C4)c2)C1 -US20060270656A1,1,CC(=O)Nc1nc(C#N)c(Cl)s1.Nc1ccccc1S>>CC(=O)Nc1nc(C#N)c(Sc2ccccc2N)s1 -US20090041723A1,6,CC(C)(C)OC(=O)N1CCOC[C@H]1C(=O)Nc1ccc(C#Cc2cn(CCO)nc2-c2cc(Cl)ccc2O)cc1>>O=C(Nc1ccc(C#Cc2cn(CCO)nc2-c2cc(Cl)ccc2O)cc1)[C@@H]1COCCN1 -US20130281438A1,2,C1CCNC1.Nc1ccccc1C(=O)O>>Nc1ccccc1C(=O)N1CCCC1 -US20150232465A1,2,CC(=O)N1c2ccc(Br)nc2NC[C@@H]1C.O=C=Nc1ccc(F)cc1>>CC(=O)N1c2ccc(Br)nc2N(C(=O)Nc2ccc(F)cc2)C[C@@H]1C -US20040132694A1,1,NC(=O)c1c(Cl)ccc(Nc2c(Cl)c(=O)c2=O)c1O.Nc1ccccc1>>NC(=O)c1c(Cl)ccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O -US20140080801A1,1,C[Si](C)(C)CCOCn1ncc([N+](=O)[O-])c1Cl.OC1CNCCNC1>>C[Si](C)(C)CCOCn1ncc([N+](=O)[O-])c1N1CCNCC(O)C1 -US07495015B2,3,CC(C)(C)OC(=O)n1nc(I)c2ccc(Oc3ccccc3F)cc21.OB(O)c1ccccc1Cl>>CC(C)(C)OC(=O)n1nc(-c2ccccc2Cl)c2ccc(Oc3ccccc3F)cc21 -US20080113984A1,7,COc1cc(-c2nnc3sc(-c4ccc(C)c([N+](=O)[O-])c4)nn23)cc(OC)c1OC>>COc1cc(-c2nnc3sc(-c4ccc(C)c(N)c4)nn23)cc(OC)c1OC -US20030191240A1,1,O=C(O)c1ccc(O)cc1.OCCCl>>O=C(O)c1ccc(OCCO)cc1 -US04177257,4,N#Cc1ccc2c(c1)S(=O)(=O)c1ccccc1S2.[N-]=[N+]=[N-]>>O=S1(=O)c2ccccc2Sc2ccc(-c3nnn[nH]3)cc21 -US07989461B2,3,CNc1ncc2cc(B3OC(C)(C)C(C)(C)O3)ccc2n1.Cc1ccc2c(N)nsc2c1I>>CNc1ncc2cc(-c3c(C)ccc4c(N)nsc34)ccc2n1 -US20050054658A1,2,CC(C)(C)[Si](C)(C)OC(COC1CCC(O)CC1F)c1ccccc1.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)OC(COC1CCC(OS(C)(=O)=O)CC1F)c1ccccc1 -US20080287458A1,4,CC(=O)CCC(C)=O.Nc1cccc(Nc2cc(Cl)ccc2C(=O)O)n1>>Cc1ccc(C)n1-c1cccc(Nc2cc(Cl)ccc2C(=O)O)n1 -US20040176593A1,2,Cc1cc(Cl)c(N)c(Cl)n1.O=C(Br)CBr>>Cc1cc(Cl)c(NC(=O)CBr)c(Cl)n1 -US20120283273A1,1,Clc1cc(Cl)ncn1.NCc1ccc2[nH]c(C(F)(F)F)cc2c1>>FC(F)(F)c1cc2cc(CNc3cc(Cl)ncn3)ccc2[nH]1 -US20080171743A1,2,C[C@H]1COCCN1c1cc(C(C)(C)S(=O)(=O)C2CCCC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C(C)(C)S(=O)(=O)C2CCCC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US20030212084A1,6,C=C[C@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1CC(=O)N(C)OC>>C=C[C@H]1CNCC[C@H]1CC(=O)N(C)OC -US20130225552A1,6,CCOC(=O)C(C)(C)c1cccnc1Cl>>CC(C)(C(=O)O)c1cccnc1Cl -US20150266879A1,6,Cc1ccc(F)c(NC(=O)[C@@H]2Cc3cccnc3N2C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)C)c1>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ncccc2C[C@H]1C(=O)Nc1cc(C)ccc1F)C(C)C -US06762180B1,2,CN.CN(CC(=O)O)Cc1ccc([N+](=O)[O-])cc1>>CNC(=O)CN(C)Cc1ccc([N+](=O)[O-])cc1 -US20100119503A1,1,CC(C)[C@]1(C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)CC[C@@H](N)C1.CC1COCCC1=O>>CC1COCCC1N[C@@H]1CC[C@@](C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)(C(C)C)C1 -US20150158882A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H]1CCN[C@@H]1C(=O)O>>C[C@H]1CCN(C(=O)OC(C)(C)C)[C@@H]1C(=O)O -US20120184735A1,7,COc1c([N+](=O)[O-])cc(C(C)(C)C)cc1C(C)(C)C#N>>COc1c(N)cc(C(C)(C)C)cc1C(C)(C)C#N -US20150057295A1,3,CC(C(=O)Nc1cc(Br)c(Cl)c(C#C[Si](C(C)C)(C(C)C)C(C)C)n1)N(C)C(=O)OC(C)(C)C.Cn1ncc2cccc(B(O)O)c21>>CC(C)[Si](C#Cc1nc(NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)cc(-c2cccc3cnn(C)c23)c1Cl)(C(C)C)C(C)C -US20110263571A1,1,Brc1cnc(Br)c(Br)c1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2ncc(Br)cc2Br)CC1 -US20040209865A1,3,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.CN1C[C@@H]2C[C@@H]1N(c1ccc(I)cn1)C2>>CN1C[C@@H]2C[C@@H]1N(c1ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cn1)C2 -US20110144345A1,1,BrCc1ccc2ccccc2c1.COc1ccc(C(=O)c2cnn(C)c2O)c(Cl)c1N=C1CCCCS1=O>>COc1ccc(C(=O)c2cnn(C)c2OCc2ccc3ccccc3c2)c(Cl)c1N=C1CCCCS1=O -US07252925B2,1,CCOCCCl.CCc1nc2ccccc2[nH]1>>CCOCCn1c(CC)nc2ccccc21 -US20130079328A1,2,Cc1cc(-c2ccc(CN)cc2)ccn1.O=C(O)c1ccc(-c2ccccn2)cc1>>Cc1cc(-c2ccc(CNC(=O)c3ccc(-c4ccccn4)cc3)cc2)ccn1 -US07553979B2,3,C=CCCCC(=O)CCC(C)OC(=O)c1c(OC)cc(OC)cc1OS(=O)(=O)C(F)(F)F.C=C[Sn](CCCC)(CCCC)CCCC>>C=CCCCC(=O)CCC(C)OC(=O)c1c(C=C)cc(OC)cc1OC -US20050228006A1,6,Fc1ccc(Cn2c(N3CCC4(CC3)OCCO4)nc3ccccc32)cc1>>O=C1CCN(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1 -US06528503B2,6,COC(=O)C(O)CC1(C)CC1>>CC1(C[C@@H](O)C(=O)O)CC1 -US20060009456A1,1,C=CCI.CC(=O)c1ccc(O)c(C)c1C>>C=CCOc1ccc(C(C)=O)c(C)c1C -US20150232463A1,7,O=C(O)Cc1cc(F)c(F)cc1F>>OCCc1cc(F)c(F)cc1F -US20060030609A1,9,CCN1C(=O)Cc2cc(N3C[C@H](C(=O)OC)OC3=O)ccc21.N>>CCN1C(=O)Cc2cc(N3C[C@H](C(N)=O)OC3=O)ccc21 -US05510366,1,C=CCI.Cc1ccc(O)c2c1NC(=O)C2(C)C>>C=CCOc1ccc(C)c2c1C(C)(C)C(=O)N2 -US20140275129A1,2,CN(C)c1ccc(-c2nc(C(=O)O)c3ccccc3n2)cc1.CN(C)c1ccc2c(c1O)CCNC2>>CN(C)c1ccc(-c2nc(C(=O)N3CCc4c(ccc(N(C)C)c4O)C3)c3ccccc3n2)cc1 -US20070049632A1,1,ClCc1csc(-c2ccc(Cl)cc2)n1.Cn1[nH]c(=O)c2c1[C@]1(C)CC[C@H]2C1(C)C>>Cn1c2c(c(=O)n1Cc1csc(-c3ccc(Cl)cc3)n1)[C@H]1CC[C@]2(C)C1(C)C -US08173650B2,6,CC(C)(C)OC(=O)N1CC(N2CC(O)C2)C1>>OC1CN(C2CNC2)C1 -US08314138B2,3,Cc1nc(-c2cncc(Cl)n2)sc1C(=O)NCc1ccccc1.OB(O)/C=C/c1ccccc1>>Cc1nc(-c2cncc(/C=C/c3ccccc3)n2)sc1C(=O)NCc1ccccc1 -US20070208166A1,2,CCCCCOc1ccc(C(=O)Cl)cc1.NCC(=O)NC1CCCc2ccccc21>>CCCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 -US20070021473A1,6,CCOC(=O)c1ccc(-c2ccc(OCCCN)c(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c2)cc1>>CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCN)ccc21 -US20150031674A1,1,CC(C)(C)OC(=O)N1CCN(CCOS(C)(=O)=O)CC1.CSc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3Cl)c(=O)[nH]c2n1>>CSc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3Cl)c(=O)n(CCN3CCN(C(=O)OC(C)(C)C)CC3)c2n1 -US20080194549A1,2,CC(C)NC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1C(C)(C)O[SiH2]C(C)(C)C.CCc1ccc(C(=O)O)cc1OCCCOC>>CCc1ccc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C(C)(C)O[SiH2]C(C)(C)C)C(C)C)cc1OCCCOC -US20140187423A1,1,CCCCC(O)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl.CI>>CCCCC(Cn1cncn1)(OC)c1ccc(Oc2ccc(Cl)cc2)cc1Cl -US20090181942A1,2,CCOC(=O)/C=C/C(=O)Cl.COc1ccc(CNc2cccc(Cl)c2C(O)c2cccc(OC)c2OC)c(OC)c1>>CCOC(=O)/C=C/C(=O)N(Cc1ccc(OC)cc1OC)c1cccc(Cl)c1C(O)c1cccc(OC)c1OC -US20100113782A1,2,CCOC(=O)C1CCN(c2ccc(C(=O)O)cc2)CC1.Cc1ccc(N)cc1I>>CCOC(=O)C1CCN(c2ccc(C(=O)Nc3ccc(C)c(I)c3)cc2)CC1 -US20150252038A1,7,CC(C)(C)OC(=O)N1CCC(F)(C(=O)O)CC1>>CC(C)(C)OC(=O)N1CCC(F)(CO)CC1 -US05300506,5,COc1cncnc1N1CCN(CCCc2c[nH]c3ccc(N)cc23)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cncnc1N1CCN(CCCc2c[nH]c3ccc(NC(=O)C(F)(F)F)cc23)CC1 -US20110301155A1,6,CC(C)S(=O)(=O)c1cc(OCc2ccccc2)c2[nH]nc(Nc3nccs3)c2c1>>CC(C)S(=O)(=O)c1cc(O)c2[nH]nc(Nc3nccs3)c2c1 -US20140187553A1,3,Brc1nccc(C2CC2)n1.Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(-c4nnc(NC(C)(C)C)o4)ccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3nccc(C4CC4)n3)c3cc(-c4nnc(NC(C)(C)C)o4)ccc32)cc1 -US04382947,2,CC(C)n1cc(O)cn1.CN=C=O>>CNC(=O)Oc1cnn(C(C)C)c1 -US06610733B2,3,C=CCCCCCC(CCCC(F)(F)C(F)(F)F)C(=O)OCC.C=CC[C@H]1c2ccc(OC)cc2SC[C@@]1(C)c1ccc(OC)cc1>>CCOC(=O)C(CCCCCC=CC[C@H]1c2ccc(OC)cc2SC[C@@]1(C)c1ccc(OC)cc1)CCCC(F)(F)C(F)(F)F -US08658636B2,6,COC(=O)c1c(CN2CCC(=O)CC2)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc12>>CS(=O)(=O)c1ccc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(=O)CC3)c(C(=O)O)c2c1 -US08088767B2,1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.Cc1cc(O)ccc1[N+](=O)[O-]>>Cc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-] -US20110251194A1,6,CCOC(=O)c1c(N)n(CC)c2nc(-c3ccc(NC(=O)NCc4cccnc4)cc3)ccc2c1=O>>CCn1c(N)c(C(=O)O)c(=O)c2ccc(-c3ccc(NC(=O)NCc4cccnc4)cc3)nc21 -US20050176767A1,2,COC(=O)c1nc(SC)cc(OC)c1OCc1ccccc1.NCc1ccc(F)cc1>>COc1cc(SC)nc(C(=O)NCc2ccc(F)cc2)c1OCc1ccccc1 -US20120165334A1,7,COC(=O)c1ccc2[nH]c(Nc3cccc(OC)c3)nc2c1>>COc1cccc(Nc2nc3cc(CO)ccc3[nH]2)c1 -US20130072679A1,3,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc(Br)c1.CN1C(=O)CCc2cc(B3OC(C)(C)C(C)(C)O3)ccc21>>CN1C(=O)CCc2cc(-c3cncc(OC[C@@H]4CCN4C(=O)OC(C)(C)C)c3)ccc21 -US20100204207A1,1,COC(=O)CC(C)(C)CC=O.Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]2CCCNc3cc4c(cc32)COC4)n1>>COC(=O)CC(C)(C)CCN1CCC[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2cc3c(cc21)COC3 -US08129538B1,3,COCOC[C@@H]1C(C(=O)N(Cc2cccc(Cl)c2Cl)C2CC2)=C(OS(=O)(=O)C(F)(F)F)CCN1C(=O)OC(C)(C)C.OB(O)c1ccc(O)cc1>>COCOC[C@@H]1C(C(=O)N(Cc2cccc(Cl)c2Cl)C2CC2)=C(c2ccc(O)cc2)CCN1C(=O)OC(C)(C)C -US20110092553A1,3,COC(=O)c1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2-c2ccc(Br)cc2)cc1.CS(=O)(=O)c1cccc(B(O)O)c1>>COC(=O)c1ccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)cc1 -US08183246B2,6,COc1ccc(-c2c(-c3ccccc3)oc3ncnc(NCCCCCNC(=O)OC(C)(C)C)c23)cc1>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(NCCCCCN)c23)cc1 -US07605157B2,9,CC1CN(c2ccc(Br)cc2C=O)CC(C)O1.[C-]#N>>C[C@H]1CN(c2ccc(C#N)cc2C=O)C[C@@H](C)O1 -US07439246B2,7,O=[N+]([O-])c1ccc(Oc2ncnn3cccc23)c(F)c1>>Nc1ccc(Oc2ncnn3cccc23)c(F)c1 -US08796256B2,2,CS(=O)(=O)Cl.NCCN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O>>CS(=O)(=O)NCCN1C(=O)S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C1=O -US20110144140A1,1,Clc1cccc(-c2nccc(Cl)n2)n1.Nc1ccc(Cl)cc1>>Clc1ccc(Nc2ccnc(-c3cccc(Cl)n3)n2)cc1 -US04965368,2,CC(C)OCC1CNC(C)(C)O1.Cc1ccc(S(=O)(=O)N=C=O)cc1>>Cc1ccc(S(=O)(=O)NC(=O)N2CC(COC(C)C)OC2(C)C)cc1 -US20130261077A1,2,CC(=O)NN.O=C(Cl)c1ccc(I)cc1O>>CC(=O)NNC(=O)c1ccc(I)cc1O -US20050148631A1,3,COc1cc(Br)ccc1C#N.Cc1cccc(NS(=O)(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)n1>>COc1cc(-c2ccc(S(=O)(=O)Nc3cccc(C)n3)cc2)ccc1C#N -US20140343035A1,6,COC(=O)[C@@H]1C[C@H](n2cc(C#Cc3cc(OC)cc(OC)c3)c3c(N)ncnc32)CN1C(=O)OC(C)(C)C>>COc1cc(C#Cc2cn([C@H]3C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C3)c3ncnc(N)c23)cc(OC)c1 -US20070244125A1,1,CC(C)Br.CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N4CCS(=O)(=O)CC4)cc3c2)CC1>>CC(C)N1CCN(C(=O)c2ccc3c(c2)cc(C(=O)N2CCS(=O)(=O)CC2)n3C(C)C)CC1 -US20010018516A1,1,CI.N#Cc1ccc(N)cc1>>CNc1ccc(C#N)cc1 -US20090325930A1,3,BrC1=Cc2ccc(OCc3ccccc3)cc2CC1.COc1ccc(Br)c([N+](=O)[O-])c1>>COc1ccc(C2=Cc3ccc(OCc4ccccc4)cc3CC2)c([N+](=O)[O-])c1 -US07786163B2,8,CC(C)(C)OC(=O)NC(CCO)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC(CC=O)C(=O)OCc1ccccc1 -US05082951,10,CCOC(=O)C(CCc1cc[nH]c1C(=O)c1ccccc1)C(=O)OCC.O=C1CCC(=O)N1Br>>CCOC(=O)C(Br)(CCc1cc[nH]c1C(=O)c1ccccc1)C(=O)OCC -US20090197859A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=S(=O)(c1cccc(F)n1)N1CCC(c2ccccc2F)CC1>>CC(C)(C)OC(=O)N1CCN(c2cccc(S(=O)(=O)N3CCC(c4ccccc4F)CC3)n2)CC1 -US07745642B2,3,CNCCOC.O=C1CCCC1.[C-]#N>>COCCN(C)C1(C#N)CCCC1 -US07553838B2,1,CCC(Br)C(=O)N1N=C(c2cc(F)ccc2F)CC1(C)c1ccccc1.CN1CCNCC1>>CCC(C(=O)N1N=C(c2cc(F)ccc2F)CC1(C)c1ccccc1)N1CCN(C)CC1 -US20150252057A1,9,COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl>>COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccccc1Cl -US20110201629A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2[nH]ccc2c1>>COc1ccc2c(ccn2C(=O)OC(C)(C)C)c1 -US05498786,2,CCCCCCCC[C@@H](Br)C(=O)O.CSc1ccc2ncccc2c1N>>CCCCCCCC[C@@H](Br)C(=O)Nc1c(SC)ccc2ncccc12 -US08163952B2,3,C#C[Mg+].CN(C)c1ccc(C=O)cc1C(C)(C)C>>C#CC(O)c1ccc(N(C)C)c(C(C)(C)C)c1 -US07544690B2,9,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN=[N+]=[N-])CC1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1 -US20080119486A1,1,ClCCCI.O=C(O)c1cc(S(=O)O)ccc1O>>O=C(O)c1cc(S(=O)(=O)CCCCl)ccc1O -US03935261,7,CCCCC(CC)C(O)C=CC1CCC(O)C1CCCCCCC(=O)O>>CCCCC(CC)C(O)CCC1CCC(O)C1CCCCCCC(=O)O -US08247562B2,1,Fc1cc(I)ccn1.NCCCN1CCOCC1>>Ic1ccnc(NCCCN2CCOCC2)c1 -US09012441B2,1,COC(=O)CBr.FC(F)(F)c1cc(Br)[nH]n1>>COC(=O)Cn1nc(C(F)(F)F)cc1Br -US08754079B2,1,CO[C@@H]1CC[C@@H](Oc2cc(F)ccc2Nc2ncnc3sc(C(=O)NCCC=O)c(C)c23)CC1.OC1CCNC1>>CO[C@@H]1CC[C@@H](Oc2cc(F)ccc2Nc2ncnc3sc(C(=O)NCCCN4CCC(O)C4)c(C)c23)CC1 -US20070032485A1,6,CC[C@@H]1C[C@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OC(C)(C)C>>CC[C@@H]1C[C@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1 -US20040102634A1,3,C#CCOc1cccc(CC(OC(C)C)C(=O)OCC)c1.Cc1ccccc1I>>CCOC(=O)C(Cc1cccc(OCC#Cc2ccccc2C)c1)OC(C)C -US04642308,1,CS.Nc1ccc2ccc(Cl)nc2n1>>CSc1ccc2ccc(N)nc2n1 -US20100317679A1,7,COc1ccc2c(c1)C(=O)C1(CCN(Cc3ccccc3)CC1)C2>>COc1ccc2c(c1)C(O)C1(CCN(Cc3ccccc3)CC1)C2 -US06346625B1,9,CCOC(=O)n1cc(-n2c(-c3cn(CCCOC(C)=O)c4ccccc34)c(C(N)=O)[nH]c2=O)c2ccccc21>>CCOC(=O)n1cc(-n2c(-c3cn(CCCOC(C)=O)c4ccccc34)c(C#N)[nH]c2=O)c2ccccc21 -US08263606B2,2,CC(C)N=C=O.O=C1N(CC2CCNC2)c2ccccc2C12COc1cc3c(cc12)CCO3>>CC(C)NC(=O)N1CCC(CN2C(=O)C3(COc4cc5c(cc43)CCO5)c3ccccc32)C1 -US06235789B1,7,COc1ccc2c(c1)C(=CC#N)CCCC2>>COc1ccc2c(c1)/C(=C/CN)CCCC2 -US20080318925A1,3,COc1cccc(F)c1B(O)O.Nc1c(C(=O)NC2CC2)nnc2c(Br)cccc12>>COc1cccc(F)c1-c1cccc2c(N)c(C(=O)NC3CC3)nnc12 -US20150191439A1,1,CC(C)Cc1nc(CCl)no1.NC12CC3CC(CC(C3)C1)C2>>CC(C)Cc1nc(CNC23CC4CC(CC(C4)C2)C3)no1 -US04122274,6,CCc1ccc(NC(=O)OCc2ccccc2)nc1>>CCc1ccc(N)nc1 -US08906939B2,1,Nc1ccc(Br)cc1F.O=C1CCOCC1>>Fc1cc(Br)ccc1NC1CCOCC1 -US06326369B1,1,COC1=C(OC)C(=O)C2=C(CCC(CCO)CC2)C1=O.COc1cc(O)cc(OC)c1>>COC1=C(OC)C(=O)C2=C(CCC(CCOc3cc(OC)cc(OC)c3)CC2)C1=O -US20080261941A1,1,Brc1ccccn1.CC(C)(C)OC(=O)N1CCC(=Cc2cccc(O)c2)CC1>>CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccccn3)c2)CC1 -US05608110,2,CC(C)=CCN.O=C(O)c1ccc([N+](=O)[O-])o1>>CC(C)=CCNC(=O)c1ccc([N+](=O)[O-])o1 -US20140005188A1,1,CC(C)(C)OC(=O)N1CCC[C@H](CO)C1.Clc1cc2nccnc2c(Cl)n1>>CC(C)(C)OC(=O)N1CCC[C@H](COc2nc(Cl)cc3nccnc23)C1 -US20130168656A1,2,CCNCC.O=C(Cl)c1cccc(Br)c1>>CCN(CC)C(=O)c1cccc(Br)c1 -US20120270875A1,6,COC(=O)[C@H](CNC(=O)c1cccs1)NC(=O)c1c(C)nc(NCC#Cc2cccc(O)c2)nc1C>>Cc1nc(NCC#Cc2cccc(O)c2)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O -US04444775,7,O=C(O)C=CCCCc1cccc2cncn12>>O=C(O)CCCCCc1cccc2cncn12 -US04077958,1,BrCCCCBr.O=C1NC(=O)c2cccc3cccc1c23>>O=C1c2cccc3cccc(c23)C(=O)N1CCCCBr -US20100137313A1,1,COc1cc(Nc2ncc(Br)c(Cl)n2)cc(OC)c1.c1cc(C2CC2)n[nH]1>>COc1cc(Nc2ncc(Br)c(-n3ccc(C4CC4)n3)n2)cc(OC)c1 -US20040152714A1,6,COc1cc(CNc2nc(C)nc(C)c2Cl)ccc1OCc1ccccc1>>COc1cc(CNc2nc(C)nc(C)c2Cl)ccc1O -US20110183959A1,3,Brc1cccc(Br)n1.N#Cc1ccc(F)c(CBr)c1>>N#Cc1ccc(F)c(Cc2cccc(Br)n2)c1 -US20140100231A1,1,CI.COc1n[nH]c(=O)cc1Cn1cnc(C(F)(F)F)c(Oc2cc(Cl)cc(C#N)c2)c1=O>>COc1nn(C)c(=O)cc1Cn1cnc(C(F)(F)F)c(Oc2cc(Cl)cc(C#N)c2)c1=O -US06720423B2,9,CCCCCCC(O)c1ccccc1Br>>CCCCCCCc1ccccc1Br -US08173650B2,2,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCNCC3(C)C)sc2n1.C[C@H](O)C(=O)O>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(=O)[C@H](C)O)CC3(C)C)sc2n1 -US20040063757A1,6,COc1cc(NCCCNC(=O)OC(C)(C)C)nc2ccccc12>>COc1cc(NCCCN)nc2ccccc12 -US20130281433A1,6,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccn4c(C)nnc4c3)sc2c1-c1ccc(Cl)cc1>>Cc1cc2nc(-c3ccn4c(C)nnc4c3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O -US07125896B2,1,Brc1ccc(Br)nc1.OC1CCOC1>>Brc1ccc(OC2CCOC2)nc1 -US07005440B1,7,CCc1ccc(CCOc2cccc(OC(=O)c3ccccc3)c2)nc1>>CCc1ccc(CCOc2cccc(O)c2)nc1 -US09050344B2,2,CC(=O)Nc1ccc(Br)c(C(=O)O)n1.CNOC>>CON(C)C(=O)c1nc(NC(C)=O)ccc1Br -US07067534B1,1,C[C@H](CCl)CBr.Oc1ccc(F)cc1>>C[C@H](CCl)COc1ccc(F)cc1 -US06670388B1,2,Cc1cc(O)ccc1Cl.O=S(=O)(Cl)c1ccccc1>>Cc1cc(OS(=O)(=O)c2ccccc2)ccc1Cl -US05576324,6,Cc1cc2c(c3c1NC(=O)CC3)OC(CNNC(=O)OCc1ccccc1)C2>>Cc1cc2c(c3c1NC(=O)CC3)OC(CNN)C2 -US20130237525A1,1,BrCC1CC1.COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccc(O)cc1>>COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccc(OCC2CC2)cc1 -US20120263706A1,7,CC(=O)c1c(Cl)ccc(F)c1Cl>>CC(O)c1c(Cl)ccc(F)c1Cl -US05262533,8,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)C(Oc4ccccc4)C3)C(C)C(O[Si](C(C)C)(C(C)C)C(C)C)CC1=O)C(C)CC2OC>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(=O)C(Oc4ccccc4)C3)C(C)C(O[Si](C(C)C)(C(C)C)C(C)C)CC1=O)C(C)CC2OC -US05929097,1,BrCc1cccc(Br)c1.COC(=O)c1cc(C)cc(C)c1NS(=O)(=O)c1ccc(OC)cc1>>COC(=O)c1cc(C)cc(C)c1N(Cc1cccc(Br)c1)S(=O)(=O)c1ccc(OC)cc1 -US20090030012A1,6,CC(C)(C)OC(=O)N1CCC(c2cccc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)CC1>>FC(F)(F)c1cc(-c2cccc(C3CCNCC3)n2)cc(C(F)(F)F)c1 -US20060084690A1,1,CC(C)OP(OC(C)C)OC(C)C.O=[N+]([O-])c1ccc(CBr)cc1>>CC(C)OP(=O)(Cc1ccc([N+](=O)[O-])cc1)OC(C)C -US06787543B2,3,COc1ccc(Br)cc1CN1C[C@@H]2CCCN2[C@H](C(c2ccccc2)c2ccccc2)C1.OB(O)c1ccccc1>>COc1ccc(-c2ccccc2)cc1CN1C[C@@H]2CCCN2[C@H](C(c2ccccc2)c2ccccc2)C1 -US20080064699A1,4,NC(N)=S.O=C1c2nonc2CCC1Br>>Nc1nc2c(s1)CCc1nonc1-2 -US07560546B2,1,CCCI.NC(=O)c1[nH]c2ccc(O)cc2c1S(=O)(=O)N1CCOCC1>>CCCOc1ccc2[nH]c(C(N)=O)c(S(=O)(=O)N3CCOCC3)c2c1 -US20090069288A1,2,COc1ccc(-c2cc(N)on2)cc1.Cc1ccccc1C(=O)Cl>>COc1ccc(-c2cc(NC(=O)c3ccccc3C)on2)cc1 -US20070105900A1,1,COCCN.O=Cc1nc(-c2nn(C3CCCCO3)cc2NC(=O)c2c(F)cccc2F)[nH]c1-c1ccc(F)cc1>>COCCNCc1nc(-c2nn(C3CCCCO3)cc2NC(=O)c2c(F)cccc2F)[nH]c1-c1ccc(F)cc1 -US20090239845A1,1,C1COCCN1.Cc1cc(NC(=O)c2cnc(Cl)c(Cl)c2)nn1Cc1cc(Cl)ccc1OCC(C)C>>Cc1cc(NC(=O)c2cnc(N3CCOCC3)c(Cl)c2)nn1Cc1cc(Cl)ccc1OCC(C)C -US08691810B2,6,COCOC1(c2ncc(-c3c(Cl)cnc4c3cc(-c3ccc(C(=O)O)cc3)n4S(=O)(=O)c3ccc(C)cc3)s2)CCC1>>Cc1ccc(S(=O)(=O)n2c(-c3ccc(C(=O)O)cc3)cc3c(-c4cnc(C5(O)CCC5)s4)c(Cl)cnc32)cc1 -US20060281743A1,6,COc1ccc2c(=O)n(C)c(C3CCCN(C(=O)OCc4ccccc4)C3)c(-c3ccccc3)c2c1>>COc1ccc2c(=O)n(C)c(C3CCCNC3)c(-c3ccccc3)c2c1 -US07262212B2,7,C[C@@](O)(COC(=O)c1ccc([N+](=O)[O-])cc1)Cn1cc([N+](=O)[O-])nc1Cl>>C[C@@](O)(CO)Cn1cc([N+](=O)[O-])nc1Cl -US20100075994A1,7,Oc1ccc(C2=CCCCC2)nc1>>Oc1ccc(C2CCCCC2)nc1 -US20100048568A1,6,CC(=O)NN1CC(c2ccc(F)cc2)=NNC1=O>>NN1CC(c2ccc(F)cc2)=NNC1=O -US06770662B2,3,CN(C)C=O.COc1cc(C)c(Br)cc1OCc1ccccc1>>COc1cc(C)c(C=O)cc1OCc1ccccc1 -US04499299,2,CO.Cc1ccc(C(=O)Cl)cc1>>COC(=O)c1ccc(C)cc1 -US20030232852A1,7,Cc1nc(Oc2ccccc2)c([N+](=O)[O-])c(NCC(C)(C)O)c1C>>Cc1nc(Oc2ccccc2)c(N)c(NCC(C)(C)O)c1C -US20140235628A1,2,Cc1c(SCC2CC[NH2+]CC2)ccc2c1COC2=O.O=C(O)Cc1ccc(-n2cnnn2)nc1>>Cc1c(SCC2CCN(C(=O)Cc3ccc(-n4cnnn4)nc3)CC2)ccc2c1COC2=O -US20140275178A1,2,Nc1ccc(F)cc1.O=C(O)c1sc(-c2ccccc2)nc1-c1ccccc1>>O=C(Nc1ccc(F)cc1)c1sc(-c2ccccc2)nc1-c1ccccc1 -US20050137243A1,7,O=C(Nc1ccc([N+](=O)[O-])cc1)Nc1ccc2c(cnn2CCN2CCCC2)c1>>Nc1ccc(NC(=O)Nc2ccc3c(cnn3CCN3CCCC3)c2)cc1 -US20090069340A1,1,Cn1c(CBr)c(F)c(=O)n1-c1ccccc1.O=C1NCN(c2ccccc2)C12CCNCC2>>Cn1c(CN2CCC3(CC2)C(=O)NCN3c2ccccc2)c(F)c(=O)n1-c1ccccc1 -US08921397B2,2,CC(C)(C)Oc1ccc(C(=O)O)cc1.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CC(C)(C)Oc1ccc(C(=O)N[C@@H]2CC[C@@H](CCN3CCCCC3c3coc4cccc-4c3)CC2)cc1 -US20110076291A1,3,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CC1(C)C(=O)NC(=O)N1c1nc2c(s1)CCOc1cc(Br)ccc1-2>>CC(C)(C)OC(=O)N1CC=C(c2ccc3c(c2)OCCc2sc(N4C(=O)NC(=O)C4(C)C)nc2-3)CC1 -US20120059002A1,3,C=C[Sn](CCCC)(CCCC)CCCC.Cc1cc(-c2nc3ccc(Br)cc3c(=O)[nH]2)cc(C)c1OCCO[Si](C)(C)C(C)(C)C>>C=Cc1ccc2nc(-c3cc(C)c(OCCO[Si](C)(C)C(C)(C)C)c(C)c3)[nH]c(=O)c2c1 -US20130237535A1,3,CC1(C)OB(c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)OC1(C)C.CN(C(N)=O)c1n[nH]c2cc(Br)ccc12>>CN(C(N)=O)c1n[nH]c2cc(-c3ccc(S(=O)(=O)N4CCC5(CC4)CN(C4CC4)C(=O)CO5)cc3)ccc12 -US20120252779A1,1,C1COCCN1.O=Cc1ccccc1F>>O=Cc1ccccc1N1CCOCC1 -US20070149577A1,3,COc1ccc(F)cc1B(O)O.O=Cc1ccc(Br)cc1>>COc1ccc(F)cc1-c1ccc(C=O)cc1 -US07105567B2,2,CC(C)c1cccc(C(C)C)c1N=C=O.CSc1ccc(CNc2ccc(C(C)C)cc2)cc1>>CSc1ccc(CN(C(=O)Nc2c(C(C)C)cccc2C(C)C)c2ccc(C(C)C)cc2)cc1 -US20140051708A1,2,CCOC(=O)c1cc(C(C)=O)nn1C.CCc1cccc(CC)c1N>>CCc1cccc(CC)c1NC(=O)c1cc(C(C)=O)nn1C -US20070219187A1,6,CN(C(=O)[C@H]1CCCN(C(=O)OC(C)(C)C)C1)c1ccc(F)cc1>>CN(C(=O)[C@H]1CCCNC1)c1ccc(F)cc1 -US20030144326A1,1,NC[C@H](O)COc1ccccc1.O=C1CCN(c2ccc(C=C3SC(=S)NC3=O)cc2)CC1>>O=C1NC(=S)SC1=Cc1ccc(N2CCC(NC[C@H](O)COc3ccccc3)CC2)cc1 -US20060264429A1,1,CC1CN(C(=O)OC(C)(C)C)CCN1.Cc1ccc2c(OS(=O)(=O)C(F)(F)F)cccc2n1>>Cc1ccc2c(N3CCN(C(=O)OC(C)(C)C)CC3C)cccc2n1 -US20100113502A1,1,CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(C)(=O)=O)CCNC2)CC1.O=C1CCC1>>CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(C)(=O)=O)CCN(C3CCC3)C2)CC1 -US09120749B2,1,CC(=O)c1cnc2ccc(Br)cc2c1Cl.CN(C)CCNc1ccc(N)cn1>>CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(NCCN(C)C)nc1 -US06441017B1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(N[C@H]1CCNC1)C(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](NC(=O)C(F)(F)F)C1 -US20140322229A1,2,COC(=O)c1ccc(Cc2c3n(c4ccccc24)CN(C)CC3)cc1.NO>>CN1CCc2c(Cc3ccc(C(=O)NO)cc3)c3ccccc3n2C1 -US07772244B2,2,C1CCNCC1.Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)O)cc2cn[nH]c12>>Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)N2CCCCC2)cc2cn[nH]c12 -US20050148634A1,6,Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2n1NC(=O)OC(C)(C)C>>Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2n1N -US03993768,7,Nc1ccc(OCCCCOc2ccccc2)cc1[N+](=O)[O-]>>Nc1ccc(OCCCCOc2ccccc2)cc1N -US20060252790A1,2,CCn1ncc2c(NC3CCOCC3)c(C(=O)NN)cnc21.O=C(Cl)C1CC1>>CCn1ncc2c(NC3CCOCC3)c(C(=O)NNC(=O)C3CC3)cnc21 -US07462620B2,6,CCc1cn(CC(=O)OC(C)(C)C)c(CCc2ccc(F)cc2)nc1=O>>CCc1cn(CC(=O)O)c(CCc2ccc(F)cc2)nc1=O -US06096763,9,BrC(Br)(Br)Br.O=C1c2c(ccc3c2OCCO3)S(=O)(=O)N1CCCCO>>O=C1c2c(ccc3c2OCCO3)S(=O)(=O)N1CCCCBr -US03933838,4,NC(N)=S.O=C(O)CC(Br)C(=O)c1ccc(F)cc1>>Nc1nc(-c2ccc(F)cc2)c(CC(=O)O)s1 -US20120129840A1,6,COC(=O)C(Cc1ccccc1)c1c(C)nc(N2CCCCC2)nc1-c1ccc(C)cc1>>Cc1ccc(-c2nc(N3CCCCC3)nc(C)c2C(Cc2ccccc2)C(=O)O)cc1 -US20130245016A1,7,Cc1cc(C2CC2)c(C#N)c(=O)[nH]1>>Cc1cc(C2CC2)c(CN)c(=O)[nH]1 -US20060058361A1,6,COc1ccc2occc2c1>>Oc1ccc2occc2c1 -US20090018166A1,2,CCO.O=C(Cl)c1cc(F)c(Cl)nc1Cl>>CCOC(=O)c1cc(F)c(Cl)nc1Cl -US20140378459A1,7,O=C(O)CCc1ccc(OCc2ccccc2)cc1Cl>>OCCCc1ccc(OCc2ccccc2)cc1Cl -US20130116285A1,1,N#Cc1ccc(F)c(Br)c1.Oc1ccc(Cl)cc1>>N#Cc1ccc(Oc2ccc(Cl)cc2)c(Br)c1 -US20080305169A1,1,O=C(CCl)Nc1c(O)ccc2ccccc12>>O=C1COc2ccc3ccccc3c2N1 -US20070117798A1,1,Cc1c[nH]cn1.O=Cc1ccc(F)c(F)c1>>Cc1cn(-c2ccc(C=O)cc2F)cn1 -US20110207704A1,6,CCOC(=O)[C@@H]1CC[C@H](Nc2ccc(-c3noc(-c4cnc(OC(C)C)c(Br)c4)n3)cc2)C1>>CC(C)Oc1ncc(-c2nc(-c3ccc(N[C@H]4CC[C@@H](C(=O)O)C4)cc3)no2)cc1Br -US20060154930A1,9,FC(F)(F)c1ccc(Nc2nc(Br)c3cc(-c4ncccc4C(F)(F)F)cnn23)cc1.[C-]#N>>N#Cc1nc(Nc2ccc(C(F)(F)F)cc2)n2ncc(-c3ncccc3C(F)(F)F)cc12 -US20100069380A1,6,CC(=O)N(C1=CC(C)NN1C)c1ccc(OC(F)(F)F)cc1>>CC1C=C(Nc2ccc(OC(F)(F)F)cc2)N(C)N1 -US07238714B2,1,C[C@H](NC(=O)c1cc(Cl)cnc1Cl)c1ccc(C(=O)OC(C)(C)C)cc1.Oc1ccc(-c2ccccn2)cc1>>C[C@H](NC(=O)c1cc(Cl)cnc1Oc1ccc(-c2ccccn2)cc1)c1ccc(C(=O)OC(C)(C)C)cc1 -US20090286778A1,2,Cc1cc(C(=O)Cl)no1.O=C(C[C@@H]1CCCNC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2>>Cc1cc(C(=O)N2CCC[C@@H](CC(=O)Nc3ccc4cc3CCc3cncc(c3)Nc3ncc(Cl)c(n3)N4)C2)no1 -US20110152273A1,1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.COc1ccc(CN2C(=O)c3c(Cl)nc(Cl)c(F)c3C2(C)C)c(OC)c1>>COc1ccc(CN2C(=O)c3c(Cl)nc(N[C@@H]4CCCC[C@@H]4NC(=O)OC(C)(C)C)c(F)c3C2(C)C)c(OC)c1 -US05622976,7,COc1cccc(C(=O)N2CCC(CCN)CC2)c1>>COc1cccc(CN2CCC(CCN)CC2)c1 -US05968875,2,CCC(C)(C)O.O=C(O)c1cc(Cl)c(Cl)nc1Cl>>CCC(C)(C)OC(=O)c1cc(Cl)c(Cl)nc1Cl -US20150259327A1,1,N#Cc1ccc(Oc2c(F)cc(Br)cc2C#N)cc1Cl.SCc1ccccc1>>N#Cc1ccc(Oc2c(F)cc(SCc3ccccc3)cc2C#N)cc1Cl -US08039487B2,6,COC(=O)c1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)c1>>O=C(O)c1cccc(-c2nc([C@H]3CCCCN3C(=O)COc3ccccc3)cs2)c1 -US07799947B2,2,COc1cc(Cl)cc(CO)c1.CS(=O)(=O)Cl>>COc1cc(Cl)cc(COS(C)(=O)=O)c1 -US20100029621A1,6,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(N)c(Cl)c2)CC1>>Nc1ccc(C(=O)N2CCNCC2)cc1Cl -US07402684B2,6,COC(=O)CCN1CCCC[C@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1>>O=C(O)CCN1CCCC[C@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1 -US20080249093A1,3,CC(C)C[Zn+].CCOC(=O)c1cnc(Cl)c(C#N)c1>>CCOC(=O)c1cnc(CC(C)C)c(C#N)c1 -US20070265278A1,2,NC1CCCCC1.O=S(=O)(Cl)c1cccc(Br)c1>>O=S(=O)(NC1CCCCC1)c1cccc(Br)c1 -US20070129416A1,2,CCOc1cc(OC)c(S(=O)(=O)N2CCCC2)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCCN1CCNCC1>>CCOc1cc(OC)c(S(=O)(=O)N2CCCC2)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1 -US20150225369A1,1,CNC(=O)c1cc(Cl)ccn1.Cc1cc(CC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)ccc1O>>CNC(=O)c1cc(Oc2ccc(CC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2C)ccn1 -US07745641B2,9,Nc1ccc(Br)c2c1C(=O)NC2>>Nc1cccc2c1C(=O)NC2 -US20110319380A1,2,O=C1CCC(CO)N1.O=S(=O)(Cl)c1ccccc1>>O=C1CCC(COS(=O)(=O)c2ccccc2)N1 -US07592477B2,1,CCCCCCCCCCCCNC(=O)c1ccc(C=O)cc1.CCCCc1oc2ccccc2c1CN>>CCCCCCCCCCCCNC(=O)c1ccc(CNCc2c(CCCC)oc3ccccc23)cc1 -US20060258666A1,2,Nc1ccccc1N1CCCCC1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>O=C(Nc1ccccc1N1CCCCC1)c1ccc([N+](=O)[O-])o1 -US20030099785A1,2,C=C(C)C(=O)O.COc1cc(-c2nc3ccccc3s2)cc(OC)c1OCCCCCCO>>C=C(C)C(=O)OCCCCCCOc1c(OC)cc(-c2nc3ccccc3s2)cc1OC -US06949648B2,6,COC(=O)c1ccc2[nH]c3c(c(C)nn3-c3ccccn3)c(=O)c2c1>>Cc1nn(-c2ccccn2)c2[nH]c3ccc(C(=O)O)cc3c(=O)c12 -US20150175617A1,2,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=C1NN=C2CNCc3[nH]c4cccc1c4c32>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CC2=NNC(=O)c3cccc4[nH]c(c2c34)C1 -US20120088793A1,7,CCC1CCN(CC#N)CC1>>CCC1CCN(CCN)CC1 -US04052407,7,CCCCCC(=O)/C=C/c1scnc1CCCCCCC(=O)OC>>CCCCCC(O)/C=C/c1scnc1CCCCCCC(=O)OC -US20110319378A1,1,CCC(Br)CC.CSC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)NC1=O>>CCC(CC)N1C(=O)[C@@](C)(CSC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US20140275006A1,1,C1COCCN1.CC(=O)Cc1ccc(Cl)nc1>>CC(Cc1ccc(Cl)nc1)N1CCOCC1 -US20120142668A1,6,COC(=O)/C=C/[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1cccs1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1cccs1)C(=O)N[C@H](/C=C/C(=O)O)CCc1ccccc1 -US20140206585A1,1,CN(C)c1ccc(N)cc1.CN(C)c1ncc(Br)cn1>>CN(C)c1ccc(Nc2cnc(N(C)C)nc2)cc1 -US20110112063A1,7,Cc1cc(Br)c(C#N)cc1[N+](=O)[O-]>>Cc1cc(Br)c(C#N)cc1N -US07557127B2,2,CCOC(=O)/C=C/c1ccc(N[C@@H]2CCCNC2)nc1.O=C(O)C1CCCCC1>>CCOC(=O)/C=C/c1ccc(N[C@@H]2CCCN(C(=O)C3CCCCC3)C2)nc1 -US20080221107A1,1,O=c1[nH]ncc2cc(-c3ccc(Cl)cc3)sc12.O[C@@H]1CCN(c2ccc(Br)nc2)C1>>O=c1c2sc(-c3ccc(Cl)cc3)cc2cnn1-c1ccc(N2CC[C@@H](O)C2)cn1 -US20050288273A1,3,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCCC3=O)C(=O)O1.O=Cc1ccc(F)cc1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(=Cc2ccc(F)cc2)C3=O)C(=O)O1 -US20140378483A1,3,CC(C)(C)OC(=O)COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.COC(=O)Cn1c(=O)[nH]c2ccc(C(=O)c3c(C)c(Br)c4ccccn34)cc2c1=O>>COC(=O)Cn1c(=O)[nH]c2ccc(C(=O)c3c(C)c(-c4ccc(OCC(=O)OC(C)(C)C)cc4)c4ccccn34)cc2c1=O -US20090137609A1,6,CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(C(O)C(=O)OC)cc2)c(C)c1>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(C(O)C(=O)OC)cc2)c(C)c1 -US20060041164A1,6,COC(=O)Cc1cc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)ccc1Br>>O=C(O)Cc1cc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)ccc1Br -US08507484B2,7,CCOC(=O)c1cnc(Nc2ccccc2)nc1>>OCc1cnc(Nc2ccccc2)nc1 -US20050250784A1,2,COC(=O)c1cnc(N2CCN(S(=O)(=O)c3cccs3)CC2)s1.NO>>O=C(NO)c1cnc(N2CCN(S(=O)(=O)c3cccs3)CC2)s1 -US08691822B2,1,C=CCBr.COC(=O)c1ccc([N+](=O)[O-])c(O)c1>>C=CCOc1cc(C(=O)OC)ccc1[N+](=O)[O-] -US20060040985A1,4,C[S+](C)(C)=O.O=C1CN(C(c2ccccc2)c2ccccc2)C1>>c1ccc(C(c2ccccc2)N2CC3(CO3)C2)cc1 -US06818663B2,1,CCN(CC)CCO.O=[N+]([O-])c1ccc(F)cc1>>CCN(CC)CCOc1ccc([N+](=O)[O-])cc1 -US20090318541A1,7,CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2s1>>CCOC(=O)c1cc2cc(N)ccc2s1 -US20110097269A1,2,CC(=O)OC(C)=O.COc1ccc(OCCOC2CCCCO2)c(CNc2cc(F)ccc2Oc2ccccc2)c1>>COc1ccc(OCCOC2CCCCO2)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1 -US20130274469A1,2,CC(C)N.Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccncn2)c1COc1ccc(C(=O)NC(C)C)cn1 -US20070213348A1,7,COC(=O)CCc1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(O)cc2)cc1>>CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(CCCO)cc2)CC(C)(C)C1 -US20110172236A1,6,COc1ccc(CN2C[C@@H](C(C)(C)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2=O)cc1>>CC(C)([C@@H]1CNC(=O)C1)S(=O)(=O)c1cccc(C(F)(F)F)c1 -US08389717B2,7,COc1cc([N+](=O)[O-])ccc1-n1cnc(CO)c1>>COc1cc(N)ccc1-n1cnc(CO)c1 -US20080287493A1,2,CCOc1ccc(-c2cccc(OC)c2)cc1C(=O)O.N[C@@H](CCO)Cc1c[nH]c2ccccc12>>CCOc1ccc(-c2cccc(OC)c2)cc1C(=O)N[C@@H](CCO)Cc1c[nH]c2ccccc12 -US06589970B2,6,CCCCc1oc2ccccc2c1C(=O)Nc1ccc2c(Br)c(OC(Cc3ccccc3)C(=O)OC)ccc2c1>>CCCCc1oc2ccccc2c1C(=O)Nc1ccc2c(Br)c(OC(Cc3ccccc3)C(=O)O)ccc2c1 -US05990105,1,CN.Cc1cc(S(=O)(=O)c2ccc(N)cc2)cc(Br)n1>>CNc1cc(S(=O)(=O)c2ccc(N)cc2)cc(C)n1 -US20140128390A1,3,CC(C)(C)OC(=O)N1CC=C(c2cc3ncnc(Cl)c3s2)CC1.CC1(C)OB(c2ccc(NS(=O)(=O)C3CC3)cc2)OC1(C)C>>CC(C)(C)OC(=O)N1CC=C(c2cc3ncnc(-c4ccc(NS(=O)(=O)C5CC5)cc4)c3s2)CC1 -US06043366,1,N#CCBr.O=C1NCN(c2ccccc2)C12CCN(C1CCCCCCCCC1)CC2>>N#CCN1CN(c2ccccc2)C2(CCN(C3CCCCCCCCC3)CC2)C1=O -US20100311966A1,2,CCCCOC(=O)c1nc(N2CC[C@H](N)[C@H](OCCC)C2)oc1CC.CCc1[nH]c(C(=O)O)nc1Cl>>CCCCOC(=O)c1nc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](OCCC)C2)oc1CC -US20040138286A1,6,CC(C)(C)OC(=O)NC1CCCN(Cc2ccccc2)C1>>NC1CCCN(Cc2ccccc2)C1 -US20120172235A1,9,BrC(Br)(Br)Br.OCc1cc(CO)cc(CO)c1>>OCc1cc(CO)cc(CBr)c1 -US09115139B2,1,CCC(C)NC.Clc1cncc(Cl)n1>>CCC(C)N(C)c1cncc(Cl)n1 -US20140275070A1,2,FC(F)(F)Cc1cc2c(N3CCNCC3)ncnc2s1.NS(=O)(=O)Cc1ccc(CC(=O)O)cc1>>NS(=O)(=O)Cc1ccc(CC(=O)N2CCN(c3ncnc4sc(CC(F)(F)F)cc34)CC2)cc1 -US20120296074A1,7,CCCCCCCCCCCCCCCCCCCCCCOc1ccc(C=O)c(OCCCCCCCCCCCCCCCCCCCCCC)c1>>CCCCCCCCCCCCCCCCCCCCCCOc1ccc(CO)c(OCCCCCCCCCCCCCCCCCCCCCC)c1 -US20110021352A1,4,CCOC(=O)CC(=O)C(F)(F)F.Nc1ncc(Cl)cc1C=O>>CCOC(=O)c1cc2cc(Cl)cnc2nc1C(F)(F)F -US20090048269A1,3,Cc1ccc(Oc2ccnc(Cl)c2)c(I)n1.Cc1cscc1B(O)O>>Cc1ccc(Oc2ccnc(Cl)c2)c(-c2cscc2C)n1 -US20100286125A1,1,CC(C)(C)OC(=O)N1CCNCC1.COC(=O)[C@H](CC=O)C[C@@H](OC)c1ccc(F)cc1>>COC(=O)[C@@H](CCN1CCN(C(=O)OC(C)(C)C)CC1)C[C@@H](OC)c1ccc(F)cc1 -US20150191476A1,9,BrC(Br)(Br)Br.OCc1ncc(C2CC2)cn1>>BrCc1ncc(C2CC2)cn1 -US20070060566A1,2,N#Cc1ccc(C(=O)Cl)cc1.Nc1ccc2c(c1)CCN(C1CCC1)CC2>>N#Cc1ccc(C(=O)Nc2ccc3c(c2)CCN(C2CCC2)CC3)cc1 -US20150252022A1,4,C#Cc1ccc2c(ccn2CC2CCN(C(=O)CCc3ccccc3)CC2)c1.[N-]=[N+]=[N-]>>O=C(CCc1ccccc1)N1CCC(Cn2ccc3cc(-c4c[nH]nn4)ccc32)CC1 -US06060468,1,Clc1cc(Cl)c2c(c1)CC(Cl)c1ccccc1S2.OCCBr>>Clc1cc(Cl)c2c(c1)CC(OCCBr)c1ccccc1S2 -US20060189577A1,3,C#CC[Si](C)(C)C.CCc1c(I)[nH]c(C=O)c1C(=O)OC>>CCc1c(C#CC[Si](C)(C)C)[nH]c(C=O)c1C(=O)OC -US05466697,1,ClCc1ccncc1.O=c1[nH]cc(-c2cccc(Cl)c2)c2ncccc12>>O=c1c2cccnc2c(-c2cccc(Cl)c2)cn1Cc1ccncc1 -US20090312381A1,2,CC(N)c1ccc2ccccc2c1.O=C(O)Cn1cc(-c2ccccc2)n(C2CC2)c1=O>>CC(NC(=O)Cn1cc(-c2ccccc2)n(C2CC2)c1=O)c1ccc2ccccc2c1 -US20020119992A1,6,COc1ccc(NC(c2ccc(Cl)cc2CNC(=O)[C@@H]2CCCN2C(=O)OC(C)(C)C)C(F)(F)F)cc1>>COc1ccc(NC(c2ccc(Cl)cc2CNC(=O)[C@@H]2CCCN2)C(F)(F)F)cc1 -US08183262B2,2,C1COCCN1.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)N4CCOCC4)c3)n2)n1 -US20050239656A1,2,CCCC(=O)Cl.CNC(c1cnccc1C(F)(F)F)C(C)C>>CCCC(=O)N(C)C(c1cnccc1C(F)(F)F)C(C)C -US20140178349A1,1,COCCl.C[C@@H]1CNC(=O)CO1>>COCN1C[C@@H](C)OCC1=O -US04786636,8,CCSc1ccnc(-c2cn3c(nc4ccccc43)s2)c1C.O=C(OO)c1cccc(Cl)c1>>CCSc1ccnc(C2=Cn3c(nc4ccccc43)S2=O)c1C -US20130237525A1,1,COc1ccc(CCl)cc1.COc1cccc(OC)c1C1CCCC(=O)N1>>COc1ccc(CN2C(=O)CCCC2c2c(OC)cccc2OC)cc1 -US05278318,1,CC(C)=CC(=O)Cl.Sc1ccc(Br)cc1>>CC(C)=CC(=O)Sc1ccc(Br)cc1 -US20070123527A1,7,CNC(=O)CC(c1ccccc1)c1ccc2[nH]nc(OC)c2c1>>CNCCC(c1ccccc1)c1ccc2[nH]nc(OC)c2c1 -US20090044345A1,1,CN(C)c1ccnc(-c2cc(O)cc(CCl)n2)c1.CNCc1cc(-n2cccc2)ccn1>>CN(Cc1cc(-n2cccc2)ccn1)Cc1cc(O)cc(-c2cc(N(C)C)ccn2)n1 -US20070010511A1,1,CC(C)[Si](OCCCCN1C(=O)COc2ccc(CCl)cc21)(C(C)C)C(C)C.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OCc3ccccc3)CC2O)cc1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OCc3ccccc3)CC2OCc2ccc3c(c2)N(CCCCO[Si](C(C)C)(C(C)C)C(C)C)C(=O)CO3)cc1 -US20080261987A1,2,Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O.Cc1cccc(N2CCNCC2C)c1>>Cc1cccc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2C)c1 -US20050107362A1,2,COCCC(=O)O.N[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1>>COCCC(=O)N[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1 -US20070197604A1,3,CS(=O)(=O)c1cccc(B(O)O)c1.Cc1oc(-c2ccc(Br)cc2)nc1CCN1CCCC1>>Cc1oc(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)nc1CCN1CCCC1 -US08598226B2,7,Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(C=O)c1>>Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(CO)c1 -US09133105B2,6,CCOC(=O)CCCCCC(=O)Nc1ccccc1NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)CCCCCC(=O)O -US08362236B2,6,Cc1ccc(OCc2ccccc2)cc1-c1cc(Cl)nc(N)n1>>Cc1ccc(O)cc1-c1cc(Cl)nc(N)n1 -US07910595B2,2,NCc1ccccc1Br.O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(NCc1ccccc1Br)c1ccc(Cl)c([N+](=O)[O-])c1 -US04859229,2,CN(C)C(=O)Cl.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(OCCO)c(Cl)cc2F)c1=O>>CN(C)C(=O)OCCOc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl -US07268128B2,2,CC(=O)OC(C)=O.Cc1nn(C2CCCCC2)c2c(=O)[nH]c(-c3ccc(N)cc3)nc12>>CC(=O)Nc1ccc(-c2nc3c(C)nn(C4CCCCC4)c3c(=O)[nH]2)cc1 -US20130172302A1,6,CCOC(=O)C(c1ccccc1)N1CCOCC1>>O=C(O)C(c1ccccc1)N1CCOCC1 -US20150045378A1,6,CCOC(=O)CCc1cccc(OCc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)n2)c1C>>COc1ccc(F)c(-c2ccc(COc3cccc(CCC(=O)O)c3C)nc2CC(C)(C)C)c1 -US06127354,8,CC(C)(CCO)NC(=O)OC(C)(C)C>>CC(C)(CC=O)NC(=O)OC(C)(C)C -US06403601B1,2,CCOC(=O)Cl.NCC(CCO)c1ccc(F)c(F)c1>>CCOC(=O)NCC(CCO)c1ccc(F)c(F)c1 -US20040122001A1,2,CS(=O)(=O)Cl.N#Cc1ccc2c(c1)CCCN2CCO>>CS(=O)(=O)OCCN1CCCc2cc(C#N)ccc21 -US20090163462A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1>>Clc1ccc(Oc2ccc(OC[C@H]3CCCN3)cc2)cc1 -US20090048269A1,1,Clc1cc(I)ccn1.Oc1cccnc1>>Clc1cc(Oc2cccnc2)ccn1 -US20100298324A1,2,CN1CCC(N)CC1.COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)n1>>COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)NC4CCN(C)CC4)ccc3c2=O)n1 -US07838543B2,2,CN1CCC(CN(C)c2nc3cc(N)ccc3o2)C1.O=C(O)c1ccc(Oc2ccccc2)cc1>>CN1CCC(CN(C)c2nc3cc(NC(=O)c4ccc(Oc5ccccc5)cc4)ccc3o2)C1 -US20090298899A1,9,N#Cc1cccc(CBr)c1.[C-]#N>>N#CCc1cccc(C#N)c1 -US20140206681A1,3,COc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)ccc1B1OC(C)(C)C(C)(C)O1.Nc1nccn2c([C@@H]3CC[C@H]4CNCC(=O)N4C3)nc(Br)c12>>COc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)ccc1-c1nc([C@@H]2CC[C@H]3CNCC(=O)N3C2)n2ccnc(N)c12 -US20110034526A1,1,CC(C)c1nc2c(Cl)cccc2n1-c1cccc(O)c1.CS(=O)(=O)c1cc(Cl)cc(Cl)c1>>CC(C)c1nc2c(Cl)cccc2n1-c1cccc(Oc2cc(Cl)cc(S(C)(=O)=O)c2)c1 -US05106976,1,CC(C)CNc1ccccc1CCl.Sc1nc2ncccc2[nH]1>>CC(C)CNc1ccccc1CSc1nc2ncccc2[nH]1 -US20100094006A1,2,Cc1cc(CN)nn1-c1ccccc1.O=C(Cl)CCl>>Cc1cc(CNC(=O)CCl)nn1-c1ccccc1 -US04619787,3,CC=O.COc1ccc(CN2C(=O)C[C@H]2[C@@H]2COC(C)(C)O2)c(OC)c1>>COc1ccc(CN2C(=O)[C@H]([C@@H](C)O)[C@H]2[C@@H]2COC(C)(C)O2)c(OC)c1 -US05489693,6,COC(=O)CCc1ccc(C2CCN(c3ccc(C(C)NC(=O)OC(C)(C)C)cc3)C2=O)cc1>>COC(=O)CCc1ccc(C2CCN(c3ccc(C(C)N)cc3)C2=O)cc1 -US20150018546A1,6,COCOc1ccc(CNc2cc(=O)n(OCc3ccccc3)c3ncnc(C)c23)cc1>>Cc1ncnc2c1c(NCc1ccc(O)cc1)cc(=O)n2OCc1ccccc1 -US06838463B2,1,CC#CCOc1cc(Cl)ncn1.Oc1c(F)cccc1F>>CC#CCOc1cc(Oc2c(F)cccc2F)ncn1 -US20110028450A1,1,CC(C)(CCCO[Si](C)(C)C(C)(C)C)NC(=O)OC(C)(C)C.CI>>CN(C(=O)OC(C)(C)C)C(C)(C)CCCO[Si](C)(C)C(C)(C)C -US09073855B2,1,C1COCCN1.CC(C)(C)OC(=O)NC1CCC(=O)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](N2CCOCC2)CC1 -US08796455B2,2,CCOC(=O)Cl.Nc1ccccc1OC(F)(F)F>>CCOC(=O)Nc1ccccc1OC(F)(F)F -US05807887,3,O=Cc1cc2ccsc2cc1F.[Mg+]COCCCl>>OC(COCCCl)c1cc2ccsc2cc1F -US08673909B2,7,CCN(C(=O)OC(C)(C)C)C1CCCC(c2c[nH]c3ccc([N+](=O)[O-])cc23)C1>>CCN(C(=O)OC(C)(C)C)C1CCCC(c2c[nH]c3ccc(N)cc23)C1 -US20100093811A1,5,C=C(C)C[C@H](N)C(=O)O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=C(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O -US20090247517A1,10,Cc1nc2c(=O)n(-c3ccc(Cl)cc3)c(-c3ccc(-c4ccccc4)cc3)nc2n1-c1ccccc1.O=C1CCC(=O)N1Br>>O=c1c2nc(CBr)n(-c3ccccc3)c2nc(-c2ccc(-c3ccccc3)cc2)n1-c1ccc(Cl)cc1 -US20070021482A1,3,CC(=O)c1cccc(-c2cc(C(F)(F)F)cc3ncn(-c4ccccc4)c23)c1.C[Mg+]>>CC(C)(O)c1cccc(-c2cc(C(F)(F)F)cc3ncn(-c4ccccc4)c23)c1 -US07632857B2,1,C[C@H]1CC[C@H](C)N1.O=C(c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)N1CCC[C@H]1CO>>C[C@H]1CC[C@H](C)N1CC1CCCN1C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US20140094462A1,2,C[C@H]1CC=CC[C@@H](CC(=O)O)C(=O)N2CCC[C@H]2COC1=O.NCc1ccc(Cl)cc1>>C[C@H]1CC=CC[C@@H](CC(=O)NCc2ccc(Cl)cc2)C(=O)N2CCC[C@H]2COC1=O -US20050261331A1,4,C[Si](C)(C)C#Cc1cncnc1.Cc1cnc(N)c(I)c1>>Cc1cnc2[nH]c([Si](C)(C)C)c(-c3cncnc3)c2c1 -US20150175621A1,7,N#Cc1ncc(Sc2ccccc2)cn1>>NCc1ncc(Sc2ccccc2)cn1 -US20060025383A1,9,O=[N+]([O-])c1ccc(Cn2cc(I)c3c(Cl)ncnc32)cc1.[NH4+]>>Nc1ncnc2c1c(I)cn2Cc1ccc([N+](=O)[O-])cc1 -US06384051B1,7,CCOc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1[N+](=O)[O-]>>CCOc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1N -US20100029726A1,7,N#CC1(C(=O)N2CCCC2)CCC(S(=O)(=O)CC2CC2)CC1>>NCC1(C(=O)N2CCCC2)CCC(S(=O)(=O)CC2CC2)CC1 -US20070249670A1,2,COC(=O)C(NC(=O)c1cc2ccccc2cc1N)C1CCC2(CC1)OCCO2.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)C(NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C1CCC2(CC1)OCCO2 -US20110124633A1,2,CN1CCN(Cc2cc(/C=C/C(=O)O)cnc2N)CC1.CNCc1ccc(C)c2ccccc12>>Cc1ccc(CN(C)C(=O)/C=C/c2cnc(N)c(CN3CCN(C)CC3)c2)c2ccccc12 -US07560558B2,1,COc1cc2nccc(Cl)c2cc1OC.Cc1ccc(O)cc1C>>COc1cc2nccc(Oc3ccc(C)c(C)c3)c2cc1OC -US20080015191A1,1,CC(=O)Nc1cccc(-c2cncc(Cl)n2)c1.Nc1ccc(N2CCOCC2)cc1>>CC(=O)Nc1cccc(-c2cncc(Nc3ccc(N4CCOCC4)cc3)n2)c1 -US20060173050A1,2,CCOc1nc(C(=O)NCc2ccc(C(=O)O)cc2)cc(N)c1C#N.CN>>CCOc1nc(C(=O)NCc2ccc(C(=O)NC)cc2)cc(N)c1C#N -US20120165333A1,6,COc1ccc(-n2nnnc2-c2cc(Br)cnc2N)c(F)c1F>>Nc1ncc(Br)cc1-c1nnnn1-c1ccc(O)c(F)c1F -US20140194431A1,3,CC(C)N1CCn2c(Cc3ccc(Cl)cc3Br)nc(=O)c(OCc3ccccc3)c2C1=O.OB(O)c1cccc(F)c1>>CC(C)N1CCn2c(Cc3ccc(Cl)cc3-c3cccc(F)c3)nc(=O)c(OCc3ccccc3)c2C1=O -US08247403B2,6,CC(C)(C)OC(=O)N1CCOc2c(cccc2-c2ccsc2)C1>>c1cc2c(c(-c3ccsc3)c1)OCCNC2 -US05998433,2,O=C(O)c1ccc(C(=O)c2ccc(Cl)cc2)cc1.c1cc2c(o1)CNCC2>>O=C(c1ccc(Cl)cc1)c1ccc(C(=O)N2CCc3ccoc3C2)cc1 -US20110076291A1,2,CCN(CC)[C@@H]1CCNC1.O=C(O)c1nc2c(s1)CCOc1cc(-c3cn[nH]c3)ccc1-2>>CCN(CC)[C@@H]1CCN(C(=O)c2nc3c(s2)CCOc2cc(-c4cn[nH]c4)ccc2-3)C1 -US20120149721A1,2,CC(C)(C)OC(=O)N1CCC(N)CC1.CCc1ccc(OCC2CC2)c(-c2ncnc3c(C(=O)O)c(C)n(COCC[Si](C)(C)C)c23)c1>>CCc1ccc(OCC2CC2)c(-c2ncnc3c(C(=O)NC4CCN(C(=O)OC(C)(C)C)CC4)c(C)n(COCC[Si](C)(C)C)c23)c1 -US04894385,1,COC(=O)c1ccc(S)cc1.Cc1cc(C)c(C(Cl)Cn2ccnc2)c(C)c1>>COC(=O)c1ccc(SC(Cn2ccnc2)c2c(C)cc(C)cc2C)cc1 -US08815864B2,1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(O)ccc(F)c43)ccc21.Cc1cc(F)cc(C)c1C#N>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5cc(C)c(C#N)c(C)c5)ccc(F)c43)ccc21 -US08822689B2,2,CC(N)(C#N)Cn1nc2c(Cl)cc(Cl)c(Br)c2n1.FC(F)(F)c1ccc(C(=S)Cl)cc1>>CC(C#N)(Cn1nc2c(Cl)cc(Cl)c(Br)c2n1)NC(=S)c1ccc(C(F)(F)F)cc1 -US20110098323A1,3,CCOc1cc(C=O)ccc1O.O=C1CSC(=O)N1c1ccc(F)cc1>>CCOc1cc(C=C2SC(=O)N(c3ccc(F)cc3)C2=O)ccc1O -US20100216986A1,3,Brc1ccc[se]1.CCC1CCC(c2ccc(B(O)O)c(F)c2F)CC1>>CCC1CCC(c2ccc(-c3ccc[se]3)c(F)c2F)CC1 -US07414036B2,7,N#Cc1ccc(O)c([N+](=O)[O-])c1>>N#Cc1ccc(O)c(N)c1 -US20120107273A1,6,Cc1nc(N2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)[C@@H](C(=O)OCc3ccccc3)C2)sc1C(=O)OC(C)(C)C>>Cc1nc(N2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)[C@@H](C(=O)O)C2)sc1C(=O)OC(C)(C)C -US07135467B2,6,CCOC(=O)c1nc(N2CCCCS2(=O)=O)n(C)c(=O)c1OCc1ccccc1>>CCOC(=O)c1nc(N2CCCCS2(=O)=O)n(C)c(=O)c1O -US20090221555A1,1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.CCN1C(=O)CCC(C)(C)c2ccc(N)cc21>>CCN1C(=O)CCC(C)(C)c2ccc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)cc21 -US06949536B2,4,Cc1cc(C(=O)CC(=O)C(F)(F)F)ccc1-c1ccco1.NNc1ccc(S(N)(=O)=O)c(F)c1>>Cc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)c(F)c2)ccc1-c1ccco1 -US20130225524A1,1,CCOC(=O)c1cccc(N)c1.NS(=O)(=O)c1cnc2cc(Br)ccc2c1Cl>>CCOC(=O)c1cccc(Nc2c(S(N)(=O)=O)cnc3cc(Br)ccc23)c1 -US20150080369A1,1,Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(CN)cc2)c(C)c1.OCC1CCOCC1>>Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(CNCC3CCOCC3)cc2)c(C)c1 -US20130059853A1,1,CC(C)CBr.COc1ccc(-c2cccc3c2CCC3=O)c(OC)c1O>>COc1ccc(-c2cccc3c2CCC3=O)c(OC)c1OCC(C)C -US20080255105A1,6,CCOC(=O)c1ccc(-c2cccc(C(=O)Nc3ccc(N4CCOCC4)cc3)c2)cc1>>O=C(O)c1ccc(-c2cccc(C(=O)Nc3ccc(N4CCOCC4)cc3)c2)cc1 -US20120232283A1,6,COC(=O)c1cccc([N+](=O)[O-])c1N(Cc1ccc(-c2ccccc2-c2nnnn2Cc2ccc(OC)cc2)cc1)C(=O)OC(C)(C)C>>COC(=O)c1cccc([N+](=O)[O-])c1NCc1ccc(-c2ccccc2-c2nnnn2Cc2ccc(OC)cc2)cc1 -US20150252038A1,2,C[C@H]1CC[C@@H](Oc2cc(F)c(C(=O)O)cc2C2CC2)CN1Cc1ccc(F)cc1Cl.NS(=O)(=O)C1CC1>>C[C@H]1CC[C@@H](Oc2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc2C2CC2)CN1Cc1ccc(F)cc1Cl -US07122543B2,2,COC1=C(OC)C(=O)C(Cc2ccc(C(=O)O)c(-c3cccnc3)c2)=C(C)C1=O.COc1ccc(N)cc1>>COC1=C(OC)C(=O)C(Cc2ccc(C(=O)Nc3ccc(OC)cc3)c(-c3cccnc3)c2)=C(C)C1=O -US04042697,1,C[n+]1ccc2cc(O)ccc2c1.OC1CCOC1>>C[n+]1ccc2cc(OC3CCOC3)ccc2c1 -US06759559B2,1,C=Cc1ccc(COc2ccc(P(c3ccccc3)c3ccccc3)c(C=O)c2)cc1.N[C@@H]1CCCC[C@H]1NCc1ccccc1P(c1ccccc1)c1ccccc1>>C=Cc1ccc(COc2ccc(P(c3ccccc3)c3ccccc3)c(CN(Cc3ccccc3P(c3ccccc3)c3ccccc3)[C@@H]3CCCC[C@H]3N)c2)cc1 -US20150065482A1,7,N#Cc1ccc(CN2CCOCC2)cn1>>NCc1ccc(CN2CCOCC2)cn1 -US06884821B1,2,CCOC(=O)C(Cc1ccc(OC)c(CN)c1)OC(C)C.O=C([O-])c1ccc(C(F)(F)F)cc1F>>CCOC(=O)C(Cc1ccc(OC)c(CNC(=O)c2ccc(C(F)(F)F)cc2F)c1)OC(C)C -US20090099183A1,3,Nc1nc(Cl)cc(Cl)n1.OB(O)c1cccc(Br)c1>>Nc1nc(Cl)cc(-c2cccc(Br)c2)n1 -US07335660B2,7,C[C@@H]1CN(c2cccc3cc(F)ccc23)CCN1CCC1OCCc2cc(C#N)ccc21>>C[C@@H]1CN(c2cccc3cc(F)ccc23)CCN1CCC1OCCc2cc(CN)ccc21 -US08258134B2,2,CC(C)(O)Cn1ccc(N)n1.CN(c1ccccc1)c1cnn(C(CC2CCCC2)C(=O)O)c(=O)c1>>CN(c1ccccc1)c1cnn(C(CC2CCCC2)C(=O)Nc2ccn(CC(C)(C)O)n2)c(=O)c1 -US08093239B2,6,CC(C)(C)OC(=O)N1CCC(N2CCN(CCF)CC2)CC1>>FCCN1CCN(C2CCNCC2)CC1 -US05279764,1,CCCCCc1ccc(C(=O)O)cc1.Oc1ccc(F)c(F)c1F>>CCCCCc1ccc(C(=O)Oc2ccc(F)c(F)c2F)cc1 -US04024273,1,CCN(CC)CCCl.O=C(c1ccc(O)cc1)c1oc2ccccc2c1-c1ccccc1>>CCN(CC)CCOc1ccc(C(=O)c2oc3ccccc3c2-c2ccccc2)cc1 -US08080566B1,6,O=C(OCc1ccccc1)N1CCCC(c2cnc[nH]2)C1>>c1ncc(C2CCCNC2)[nH]1 -US08501793B2,6,CCCC[C@H](C)C[C@@H](/C=C/[C@H]1CCC(=O)[C@@H]1CCCC/C=C/C(=O)O)OC1CCCCO1>>CCCC[C@H](C)C[C@H](O)/C=C/[C@H]1CCC(=O)[C@@H]1CCCC/C=C/C(=O)O -US04067903,1,CCO.Nc1ccccc1>>CCNc1ccccc1 -US20100160648A1,7,COc1ccc2c(c1)CCC(c1ccccc1)=C2c1ccc(OCCN2CCCC2)cc1>>COc1ccc2c(c1)CC[C@H](c1ccccc1)[C@@H]2c1ccc(OCCN2CCCC2)cc1 -US06809097B1,1,COc1cc2nccc(Cl)c2cc1C#N.Cc1cc(F)c(N)cc1O>>COc1cc2nccc(Nc3cc(O)c(C)cc3F)c2cc1C#N -US06545155B2,2,CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)O)cc1Cl.Nc1nc2ccccc2o1>>CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2nc3ccccc3o2)cc1Cl -US20080194625A1,9,CC(C)(C)OC(=O)NC1CNc2ccc(Br)cc2C1.[C-]#N>>CC(C)(C)OC(=O)NC1CNc2ccc(C#N)cc2C1 -US20120289505A1,2,CCCCCCCCc1ccc(C(=O)Cl)cc1.COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O>>CCCCCCCCc1ccc(C(=O)Nc2ccc(-c3ccc4c(c3)C(=O)N([C@H](C(=O)OC)C(C)C)C4)cc2)cc1 -US05571845,9,N.O=C(O)c1cc([N+](=O)[O-])c(N(CCCl)CCCl)c([N+](=O)[O-])c1>>NC(=O)c1cc([N+](=O)[O-])c(N(CCCl)CCCl)c([N+](=O)[O-])c1 -US20150150845A1,1,C1CNCCN1.CC1(C)c2cc(OS(=O)(=O)C(F)(F)F)ccc2C(=O)c2c1[nH]c1nc(C#N)ccc21>>CC1(C)c2cc(N3CCNCC3)ccc2C(=O)c2c1[nH]c1nc(C#N)ccc21 -US20060205740A1,1,NCCN1CCOCC1.OCc1cccc(C#Cc2cncnc2Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)n1>>Fc1cccc(COc2ccc(Nc3ncncc3C#Cc3cccc(CNCCN4CCOCC4)n3)cc2Cl)c1 -US20110009454A1,2,COCc1ccc(C(=O)O)c(N)n1.COc1ccccc1Oc1cccc(CN)c1>>COCc1ccc(C(=O)NCc2cccc(Oc3ccccc3OC)c2)c(N)n1 -US20130035310A1,5,Cc1ccccc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1ccccc1NC(=O)C(F)(F)F -US20070010511A1,1,COCCCCl.c1c[nH]cn1>>COCCCn1ccnc1 -US20090221555A1,1,CCN1CCc2ccc(N)cc2CC1.CNC(=O)CCNc1nc(Cl)ncc1Cl>>CCN1CCc2ccc(Nc3ncc(Cl)c(NCCC(=O)NC)n3)cc2CC1 -US20130143892A1,2,CC(C)(C)c1noc(N2CCC(NC3CC3)CC2)n1.O=C(O)c1ccc(-c2cnco2)nc1>>CC(C)(C)c1noc(N2CCC(N(C(=O)c3ccc(-c4cnco4)nc3)C3CC3)CC2)n1 -US20110118208A1,1,C1COCCN1.O=Cc1cc(Br)ccc1F>>Fc1ccc(Br)cc1CN1CCOCC1 -US20140058098A1,6,COCc1nc(-c2cn3c(n2)-c2cnc(Cl)cc2OCC3)n(CC(F)(F)F)n1>>OCc1nc(-c2cn3c(n2)-c2cnc(Cl)cc2OCC3)n(CC(F)(F)F)n1 -US20050101614A1,3,Cn1nc2c(Br)cccc2c1Cl.OB(O)c1ccc(Cl)cc1Cl>>Cn1nc2c(-c3ccc(Cl)cc3Cl)cccc2c1Cl -US08236955B2,6,COC(=O)[C@@H]1CN(c2ccc(=O)[nH]n2)C[C@H]1c1ccc(Cl)cc1>>O=C(O)[C@@H]1CN(c2ccc(=O)[nH]n2)C[C@H]1c1ccc(Cl)cc1 -US06110934,2,CN1CCc2c(N)cccc2C1.COc1cc(C)c(Cl)cc1C(=O)O>>COc1cc(C)c(Cl)cc1C(=O)Nc1cccc2c1CCN(C)C2 -US06218385B1,9,CSc1nc(Cl)c(C#N)c(N2CCc3ccccc3CC2)n1.N>>CSc1nc(N)c(C#N)c(N2CCc3ccccc3CC2)n1 -US20100298302A1,2,CCO.Nc1ccc(C(=O)O)cc1[N+](=O)[O-]>>CCOC(=O)c1ccc(N)c([N+](=O)[O-])c1 -US20130274263A1,1,Brc1cncc(Br)c1.CCCC(N)c1ccccc1>>CCCC(Nc1cncc(Br)c1)c1ccccc1 -US04791139,5,O=Cc1ccc(F)c(Br)c1.OCCO>>Fc1ccc(C2OCCO2)cc1Br -US20110086852A2,6,CC(=O)Oc1cc2c(cc1OC(C)=O)C(=O)OC2>>CC(=O)Oc1cc2c(cc1O)COC2=O -US20070259860A1,1,CS(=O)(=O)OCc1cc(-c2cccc(Cl)c2)on1.CSC1=NCCCN1>>CSC1=NCCCN1Cc1cc(-c2cccc(Cl)c2)on1 -US20140350019A1,6,CCOC(=O)COc1ccc(F)c(NCc2cc(OC)cc(-c3cccc(F)c3)c2)c1F>>CCOC(=O)COc1ccc(F)c(NCc2cc(O)cc(-c3cccc(F)c3)c2)c1F -US07803825B2,1,COC(=O)c1ccc(CBr)cc1.c1ccc2[nH]cnc2c1>>COC(=O)c1ccc(Cn2cnc3ccccc32)cc1 -US20100222321A1,2,CC(=O)OC(C)=O.NCc1ccc(-c2nc3ccn4cnnc4c3cc2-c2ccccc2)cc1>>CC(=O)NCc1ccc(-c2nc3ccn4cnnc4c3cc2-c2ccccc2)cc1 -US20040102436A1,1,CN(C[C@H](O)c1cccc(O)c1)c1cnc(-c2ccccc2)c(-c2ccccc2)n1.COC(=O)CBr>>COC(=O)COc1cccc([C@@H](O)CN(C)c2cnc(-c3ccccc3)c(-c3ccccc3)n2)c1 -US08022062B2,1,NCc1ccc2ncccc2c1.O=C(N1CCc2ccc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F>>O=C(N1CCc2ccc(Cl)c(NCc3ccc4ncccc4c3)c2CC1)C(F)(F)F -US08389513B2,2,C[C@]1(c2cc(N)ccc2Cl)N=C(N)OCC1(F)F.O=C(O)c1ccc(Cl)cn1>>C[C@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2Cl)N=C(N)OCC1(F)F -US08673940B2,6,CCOC(=O)c1cnc(NC(=O)OC(C)(C)C)s1>>CC(C)(C)OC(=O)Nc1ncc(C(=O)O)s1 -US05310904,7,COc1ccc(C2Sc3ccccc3NC(=O)C2=O)cc1>>COc1ccc([C@@H]2Sc3ccccc3NC(=O)[C@@H]2O)cc1 -US20120149721A1,2,CCC(=O)Cl.Cc1[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc2c1C(=O)NC1CCNCC1>>CCC(=O)N1CCC(NC(=O)c2c(C)[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)CC1 -US20090264650A1,6,CC(=O)OCCNc1ccc(CC2CCN(C3CCCCC3)C2=O)c(Cl)c1>>O=C1C(Cc2ccc(NCCO)cc2Cl)CCN1C1CCCCC1 -US20150165063A1,6,CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(OCc1ccccc1)c1ccccc21>>ClC[C@@H]1CNc2cc(OCc3ccccc3)c3ccccc3c21 -US20130237535A1,1,CC(C)(C)OC(=O)N1CCC(O)(CN(C(=O)CCl)C2(C)CC2)CC1>>CC(C)(C)OC(=O)N1CCC2(CC1)CN(C1(C)CC1)C(=O)CO2 -US08546387B2,2,CC(C)(C)c1cc(N=C=O)n(-c2ccccc2)n1.Nc1nc2nccc(Oc3ccc(N)c4ccccc34)c2[nH]c1=O>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4nc(N)c(=O)[nH]c34)c3ccccc23)n(-c2ccccc2)n1 -US20100256134A1,1,CCOC(=O)c1cnc2c(Br)cnn2c1Cl.Cc1ccc(C)c(N)c1>>CCOC(=O)c1cnc2c(Br)cnn2c1Nc1cc(C)ccc1C -US20100280013A1,1,CCCc1cc(Cl)ncc1C(=O)NC.OCCN1CCNCC1>>CCCc1cc(N2CCN(CCO)CC2)ncc1C(=O)NC -US07326716B2,1,CC(C)I.O=C(O)COCCCCN1C(=O)CCC[C@@H]1/C=C/C(O)Cc1cccc(Cl)c1>>CC(C)OC(=O)COCCCCN1C(=O)CCC[C@@H]1/C=C/C(O)Cc1cccc(Cl)c1 -US04080461,7,Nc1ccc(SCC(F)(F)F)cc1[N+](=O)[O-]>>Nc1ccc(SCC(F)(F)F)cc1N -US20120289505A1,2,COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O.O=C(Cl)c1ccccc1C(F)(F)F>>COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)c4ccccc4C(F)(F)F)cc3)cc2C1=O -US20130190268A1,6,CC(C)(C)OC(=O)CCCCNC(=O)NCCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>O=C(O)CCCCNC(=O)NCCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 -US20150011508A1,3,CC(=O)CCc1nc(-c2ccc(C)c(NC(=O)OC(C)(C)C)c2)no1.C[Mg+]>>Cc1ccc(-c2noc(CCC(C)(C)O)n2)cc1NC(=O)OC(C)(C)C -US20100239219A1,2,Cc1ccc(OCCCCCCCCCCCO)cc1.O=C(O)CCSC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1ccc(OCCCCCCCCCCCOC(=O)CCSC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US20080275233A1,1,CC(C)c1ccc(N)cc1.CCOC(CBr)OCC>>CCOC(CNc1ccc(C(C)C)cc1)OCC -US20070276011A1,3,O=Cc1ccc(Br)o1.OB(O)c1cc(Cl)cc(Cl)c1>>O=Cc1ccc(-c2cc(Cl)cc(Cl)c2)o1 -US20110105530A1,2,NCc1csc(C(F)(F)F)n1.O=C(O)c1ccnc(N2CCN(Cc3ccc(F)cc3)C2=O)c1>>O=C(NCc1csc(C(F)(F)F)n1)c1ccnc(N2CCN(Cc3ccc(F)cc3)C2=O)c1 -US20140371199A1,2,CN1CCNCC1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)c(Cl)c4)nn23)cc1>>CN1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4n3)cc2Cl)CC1 -US20060106111A1,7,COC(=O)c1ccc(-c2cc(CCNC(C)=O)c3cc(OC)ccc3c2)cc1>>COc1ccc2cc(-c3ccc(CO)cc3)cc(CCNC(C)=O)c2c1 -US08034812B2,2,Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1.O=C(O)c1cccc(C(F)(F)F)c1>>O=C(Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1)c1cccc(C(F)(F)F)c1 -US04180395,1,CCOC(=O)C(C)Br.Oc1nc(F)c(Cl)cc1Cl>>CCOC(=O)C(C)Oc1nc(F)c(Cl)cc1Cl -US20150080549A1,2,CC(C)(O)C(=O)O.O=C(O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21>>CC(C)(OC(=O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O -US20120129870A1,7,O=[N+]([O-])c1ccc(N2CCN(C(c3ccccc3)c3ncco3)CC2)c(Br)c1>>Nc1ccc(N2CCN(C(c3ccccc3)c3ncco3)CC2)c(Br)c1 -US04977273,2,COC(=O)C(F)(F)Cc1c[nH]c([N+](=O)[O-])n1.NCC(F)(F)C(N)=O>>NC(=O)C(F)(F)CNC(=O)C(F)(F)Cc1c[nH]c([N+](=O)[O-])n1 -US05053414,2,CN(Cc1ccccc1)C(=O)CCC(=O)O.OC[C@@H]1CCCN1>>CN(Cc1ccccc1)C(=O)CCC(=O)N1CCC[C@H]1CO -US05536750,6,CC(C)(C)OC(=O)N[C@H]1CCC(C)(C)OC1=O>>CC1(C)CC[C@H](N)C(=O)O1 -US20130059853A1,3,CC1(C)OB(c2cccc3c2CCC3=O)OC1(C)C.COc1c(OC(F)F)ccc(Br)c1OCc1ccc(C(N)=O)cc1>>COc1c(OC(F)F)ccc(-c2cccc3c2CCC3=O)c1OCc1ccc(C(N)=O)cc1 -US20110092526A1,4,C=C(CC(=O)O)C(=O)O.C[C@@H](N)c1ccccc1>>C[C@H](c1ccccc1)N1C[C@H](C(=O)O)CC1=O -US07629374B2,2,CCCC(=O)Cl.Nc1n[nH]c2c(F)c(F)ccc12>>CCCC(=O)Nc1n[nH]c2c(F)c(F)ccc12 -US07619091B2,6,O=C(O)c1ccc2c(Cl)cc(Cl)c(OCc3ccccc3)c2n1>>O=C(O)c1ccc2c(Cl)cc(Cl)c(O)c2n1 -US08691810B2,1,CNC.O=C1CCN(c2ccc(Br)cc2)CC1>>CN(C)C1CCN(c2ccc(Br)cc2)CC1 -US06232290B1,1,CCCCCBr.COC(=O)c1cccc(O)c1>>CCCCCOc1cccc(C(=O)OC)c1 -US20140350019A1,7,COc1ccc(Cl)c(NC(=O)c2cc(-c3cccc(F)c3)ccc2F)c1Cl>>COc1ccc(Cl)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1Cl -US20100286396A1,7,COc1ccc2c(c1OC)C(C)(C)N1CCc3cc4c(cc3C1=C2)OCO4>>COc1ccc2c(c1OC)C(C)(C)N1CCc3cc4c(cc3C1C2)OCO4 -US07345180B2,2,Cc1cc2ncc(C(=O)O)cn2n1.NCC1(N)CCCC1>>Cc1cc2ncc(C(=O)NCC3(N)CCCC3)cn2n1 -US20070099885A1,7,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)NCCC[C@@H](CO)NC(=O)OCc1ccccc1 -US05728835,2,COc1ccccc1N(CCN1CCC(C(=O)c2ccc(F)cc2)CC1)C(=O)c1ccc(N)cc1.CS(=O)(=O)Cl>>COc1ccccc1N(CCN1CCC(C(=O)c2ccc(F)cc2)CC1)C(=O)c1ccc(NS(C)(=O)=O)cc1 -US07595327B2,2,CC(=O)Cl.CCOC(=O)C1(NS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)CCNCC1>>CCOC(=O)C1(NS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)CCN(C(C)=O)CC1 -US20140364433A1,1,Cc1ccc(-c2ccc(C(F)(F)F)cn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.Clc1ccc(Br)nc1>>Cc1ccc(-c2ccc(C(F)(F)F)cn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(Cl)cn2)c1 -US06414147B1,1,CCCCn1cnc2c(Cl)nc(Nc3ccc(OCC)nc3)nc21.C[O-]>>CCCCn1cnc2c(OC)nc(Nc3ccc(OCC)nc3)nc21 -US20020156276A1,1,COc1cccc(CCl)c1.O=C1NCc2ccc(N3CCN(CCC(c4ccccc4)c4ccccc4)CC3)cc21>>COc1cccc(CN2Cc3ccc(N4CCN(CCC(c5ccccc5)c5ccccc5)CC4)cc3C2=O)c1 -US08168658B2,6,COC(=O)c1ccc(CC(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)NC(Cc1ccc(C(=O)O)cc1)C(=O)OC(C)(C)C -US20150166549A1,3,CC(O)c1oc(=O)c2ccccc2c1-c1ccc(C=O)s1.CN(C)CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CC(O)c1oc(=O)c2ccccc2c1-c1ccc(C=CCN(C)C)s1 -US04197302,6,COC(=O)c1ccc(OCc2ccccc2)cn1>>COC(=O)c1ccc(O)cn1 -US20120101136A1,1,CC(C)Oc1ccc(-c2nc(-c3ccc(O)cc3)no2)cc1C#N.CCOC(=O)CCCBr>>CCOC(=O)CCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)cc1 -US20100298140A1,3,CCc1sc(Br)cc1Br.Clc1ccc(I)cc1>>CCc1sc(-c2ccc(Cl)cc2)cc1Br -US08859581B2,4,COc1cccc(C#C[Si](C)(C)C)c1.Nc1ccnc(Cl)c1I>>COc1cccc(-c2c([Si](C)(C)C)[nH]c3ccnc(Cl)c23)c1 -US20050203158A1,6,COCCn1c(NC(=O)c2ccc(C#N)cc2)nc2cc(CO[Si](C(C)C)(C(C)C)C(C)C)ccc21>>COCCn1c(NC(=O)c2ccc(C#N)cc2)nc2cc(CO)ccc21 -US03968142,9,NC(=O)Cc1ccc(C2CCCCC2)cc1>>N#CCc1ccc(C2CCCCC2)cc1 -US04330539,1,CN.C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1C[C@@H](O)C2=O>>CN[C@H]1[C@H](O)C[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C -US20110039821A1,10,CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cc(C)oc2c1.O=C1CCC(=O)N1Br>>CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cc(CBr)oc2c1 -US05391771,9,CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC>>CCOC(=O)CC(CC(=O)OCC)C(=O)OCC -US07067531B2,9,Cn1cncc1C(Cl)(c1ccoc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C.N>>Cn1cncc1C(N)(c1ccoc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C -US20070060754A1,2,CC(C)N=C=O.CCCn1c(COCC)nc2c(N)nc3cc(OC4CCNCC4)ccc3c21>>CCCn1c(COCC)nc2c(N)nc3cc(OC4CCN(C(=O)NC(C)C)CC4)ccc3c21 -US08080654B2,7,COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)O[C@@H]1C[C@H]1CCCC=Cc1nc3ccc(OC)cc3nc1O2>>COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)O[C@@H]1C[C@H]1CCCCCc1nc3ccc(OC)cc3nc1O2 -US20120178736A1,6,CN1CCN(C2CN(C(=O)OC(C)(C)C)C2)CC1=O>>CN1CCN(C2CNC2)CC1=O -US20090176774A1,2,COc1cc2nccc(Oc3ccc4c(N=C=S)cccc4c3)c2cc1OC.COc1ccc(N)cc1>>COc1ccc(NC(=S)Nc2cccc3cc(Oc4ccnc5cc(OC)c(OC)cc45)ccc23)cc1 -US07423159B2,4,NC(=S)Cc1ccc([N+](=O)[O-])cc1.O=CCCl>>O=[N+]([O-])c1ccc(Cc2nccs2)cc1 -US20120263706A1,1,C1CCN(C2CCNCC2)C1.CC(Oc1cc(-c2ccc(Br)nc2)cnc1N)c1c(Cl)ccc(F)c1Cl>>CC(Oc1cc(-c2ccc(N3CCC(N4CCCC4)CC3)nc2)cnc1N)c1c(Cl)ccc(F)c1Cl -US20120034270A1,6,CCCCCCCCc1ccc2c(c1)CCN(C(=O)C(F)(F)F)CC2>>CCCCCCCCc1ccc2c(c1)CCNCC2 -US20040110767A1,6,COc1ccc(N(Cc2ccc(OC3CCCCO3)cc2)S(=O)(=O)c2c(C)cc(C)cc2C)cc1>>COc1ccc(N(Cc2ccc(O)cc2)S(=O)(=O)c2c(C)cc(C)cc2C)cc1 -US07160901B2,7,CC(C)(C)OC(=O)N1CCN(Cc2ccc([N+](=O)[O-])cc2)CC1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(N)cc2)CC1 -US20090270361A1,2,CC(C)(O)CN.Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Oc1ccc(C(=O)O)cc1>>Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Oc1ccc(C(=O)NCC(C)(C)O)cc1 -US20140073650A1,6,CC(C)(C)OC(=O)COc1ccc(C(C)(C)C)cc1>>CC(C)(C)c1ccc(OCC(=O)O)cc1 -US04997840,1,CI.Nc1ccccc1C(=O)COC(=O)c1ccccc1>>CNc1ccccc1C(=O)COC(=O)c1ccccc1 -US20070082889A1,1,CC(C)COC(=O)N1CCNCC1.Clc1cc(Br)ccn1>>CC(C)COC(=O)N1CCN(c2ccnc(Cl)c2)CC1 -US04968829,1,CCC(C)Br.COc1ccc(S)cc1>>CCC(C)Sc1ccc(OC)cc1 -US08399681B2,3,CC(C)(C)OC(=O)N1CCN(C2=NC(=O)CS2)C[C@@H]1CO.Cc1nn(Cc2ccc(Cl)cc2C(F)(F)F)c2ccc(C=O)cc12>>Cc1nn(Cc2ccc(Cl)cc2C(F)(F)F)c2ccc(C=C3SC(N4CCN(C(=O)OC(C)(C)C)[C@@H](CO)C4)=NC3=O)cc12 -US04185992,7,Cc1ccc(C(=O)O)cc1Br>>Cc1ccc(CO)cc1Br -US20060264429A1,7,O=[N+]([O-])c1cc(Cl)cc2c1OCCO2>>Nc1cc(Cl)cc2c1OCCO2 -US20030162795A1,1,Cc1cc2cc(N)ccc2[nH]1.Clc1ccnc2cc(-c3nccs3)sc12>>Cc1cc2cc(Nc3ccnc4cc(-c5nccs5)sc34)ccc2[nH]1 -US04141899,2,CN=C=S.c1nc2c([nH]1)CCNC2>>CNC(=S)N1CCc2[nH]cnc2C1 -US20050192279A1,2,COc1cnn(C)c(=O)c1-c1ccc(C[C@H](N)C(=O)O)cc1.CS(=O)(=O)c1ccc(C(=O)Cl)c(Cl)c1>>COc1cnn(C)c(=O)c1-c1ccc(C[C@H](NC(=O)c2ccc(S(C)(=O)=O)cc2Cl)C(=O)O)cc1 -US20100093761A1,9,CCOC(=O)c1onc(-c2ccc(S(C)(=O)=O)cc2)c1N.[NH4+]>>CS(=O)(=O)c1ccc(-c2noc(C(N)=O)c2N)cc1 -US20100311966A1,2,CC(C)N.CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](OCC)C2)nc1C(=O)O>>CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](OCC)C2)nc1C(=O)NC(C)C -US04382939,1,CCN.COc1ccc2c3c(c(=O)oc2c1OC)CN(CC(C)=O)CC3>>CCNC(C)CN1CCc2c(c(=O)oc3c(OC)c(OC)ccc23)C1 -US04602041,1,N=C(N)NN.O=Cc1c(Cl)ccc([N+](=O)[O-])c1Cl>>N=C(N)NN=Cc1c(Cl)ccc([N+](=O)[O-])c1Cl -US05998433,3,C=O.CNC.O=C(c1ccccc1)c1ccc(S(=O)(=O)N2CCc3occc3C2)cc1>>CN(C)Cc1cc2c(o1)CCN(S(=O)(=O)c1ccc(C(=O)c3ccccc3)cc1)C2 -US05935563,3,CC(C)(C)C1CCC(OC(=O)CC#N)CC1.CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(C=C(C#N)C(=O)OC2CCC(C(C)(C)C)CC2)cc(C(C)(C)C)c1O -US20110184188A1,7,Cc1cc(C(O)c2cc(C(F)(F)C(F)(F)F)n[nH]2)ccc1[N+](=O)[O-]>>Cc1cc(C(O)c2cc(C(F)(F)C(F)(F)F)n[nH]2)ccc1N -US20130053409A1,1,CN(C)[C@@H]1CCNC1.COc1cc(F)c([N+](=O)[O-])cc1Nc1nccc(-c2cnn3c2CCCC3)n1>>COc1cc(N2CC[C@@H](N(C)C)C2)c([N+](=O)[O-])cc1Nc1nccc(-c2cnn3c2CCCC3)n1 -US20140114068A1,7,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NC(=O)c1ccc([N+](=O)[O-])cc1>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NC(=O)c1ccc([N+](=O)[O-])cc1 -US08044236B2,1,CC(C)(C)c1ccc(O)cc1.O=Cc1cc(-c2ccc(OC(F)(F)F)cc2)ccc1F>>CC(C)(C)c1ccc(Oc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2C=O)cc1 -US07189750B2,2,Cc1nc(N)sc1CCO[N+](=O)[O-].O=C(O)C1CCCN1>>Cc1nc(NC(=O)C2CCCN2)sc1CCO[N+](=O)[O-] -US20140235623A1,2,N#Cc1cc(F)ccc1N.NS(=O)(=O)Cl>>N#Cc1cc(F)ccc1NS(N)(=O)=O -US07115609B2,2,CN1CCC(C2CCN(C(=O)[C@H](N)Cc3cn(C)cn3)CC2)CC1.O=C(O)c1ccc2cc[nH]c2c1>>CN1CCC(C2CCN(C(=O)[C@@H](Cc3cn(C)cn3)NC(=O)c3ccc4cc[nH]c4c3)CC2)CC1 -US08273736B2,1,CC1(C)CNCC(=O)N1.COc1cc(-c2csc3c(/C=C/C=O)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C>>COc1cc(-c2csc3c(/C=C/CN4CC(=O)NC(C)(C)C4)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C -US06881844B2,1,CC(C)I.O=C(c1c[nH]c2cc(C(F)(F)F)ccc12)C(F)(F)F>>CC(C)n1cc(C(=O)C(F)(F)F)c2ccc(C(F)(F)F)cc21 -US06350759B1,1,C#CC1(O)CCCCC1.CCOc1ccc(N)cc1>>C#CC1(Nc2ccc(OCC)cc2)CCCCC1 -US05726325,1,CC(=O)Nc1cccc(O)c1.COC(=O)c1sccc1CBr>>COC(=O)c1sccc1COc1cccc(NC(C)=O)c1 -US20120302566A1,1,CC(C)(C)C(C)(O)c1cccc2c1CC[C@@H]2O[Si](C)(C)C(C)(C)C.CI>>COC(C)(c1cccc2c1CC[C@@H]2O[Si](C)(C)C(C)(C)C)C(C)(C)C -US20110065681A1,6,COC(=O)c1cc2ccc(C#N)cc2s1>>N#Cc1ccc2cc(C(=O)O)sc2c1 -US20140275015A1,7,CC1c2nnn(-c3cncnc3)c2C=CN1C(=O)c1cccc(C(F)(F)F)c1Cl>>CC1c2nnn(-c3cncnc3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl -US05968930,2,Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1.O=C(Cl)c1ccccc1F>>O=C(Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1)c1ccccc1F -US09156840B2,1,CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)NCN2c1ccccc1.COC(=O)[C@@H](Br)c1ccccc1>>COC(=O)[C@H](c1ccccc1)N1CN(c2ccccc2)C2(CCN(C(=O)OC(C)(C)C)CC2)C1=O -US20080181866A1,2,O=C(Cl)OCc1ccccc1.O=C(O)C1CS[C@H](c2ccc(F)cc2)N1>>O=C(O)C1CS[C@H](c2ccc(F)cc2)N1C(=O)OCc1ccccc1 -US06001839,2,CC(C)n1cc(-c2ccc(N)cc2)c2c(N)ncnc21.O=C(Cl)c1ccccc1>>CC(C)n1cc(-c2ccc(NC(=O)c3ccccc3)cc2)c2c(N)ncnc21 -US04500529,1,BrCCOc1cccc2c1CCC2.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCOc1cccc2c1CCC2 -US05026856,6,COc1ccc2c(c1)CN(Cc1ccccc1)C2>>COc1ccc2c(c1)CNC2 -US08053440B2,6,COC(=O)c1c(OC)cc(OC)nc1N>>COc1cc(OC)c(C(=O)O)c(N)n1 -US06239074B1,3,Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(C=O)c2)c1=O.O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)CCl>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(C=CC(=O)CCl)c2)c1=O -US20150152108A1,2,NC1CCC1.O=C(O)c1ccc2c(n1)N(C(=O)Nc1ccccn1)[C@H]1CCN2C1>>O=C(NC1CCC1)c1ccc2c(n1)N(C(=O)Nc1ccccn1)[C@H]1CCN2C1 -US07897763B2,3,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)C(=O)O.Nc1nc(Cl)cc(Cl)n1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(-c2cc(Cl)nc(N)n2)cc1)C(=O)O -US20110059948A1,6,CCOC(=O)c1c(NCc2ccccc2)nc2ccc(Br)cc2c1Cl>>O=C(O)c1c(NCc2ccccc2)nc2ccc(Br)cc2c1Cl -US20040077646A1,2,Cn1c(C(=O)NC2CCCCC2C(=O)O)cc2ccccc21.N#CC(N)c1ccccn1>>Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)NC(C#N)c2ccccn2)cc2ccccc21 -US20070105914A1,7,O=C(O)C(Oc1ccc(Cl)cc1)c1ccc(Cl)cc1>>OCC(Oc1ccc(Cl)cc1)c1ccc(Cl)cc1 -US05475106,2,CCOC(=O)c1ccccc1N(CC(=O)OC(C)(C)C)C(=O)CN.Cc1cccc(N=C=O)c1>>CCOC(=O)c1ccccc1N(CC(=O)OC(C)(C)C)C(=O)CNC(=O)Nc1cccc(C)c1 -US20110172247A1,1,CI.Clc1cc(Nc2cncnc2)cc(Cl)n1>>CN(c1cncnc1)c1cc(Cl)nc(Cl)c1 -US20100190804A1,1,COc1cccc([C@@H](C)N)c1.Clc1ncc(Cl)c(Cl)n1>>COc1cccc([C@@H](C)Nc2nc(Cl)ncc2Cl)c1 -US20090197959A1,5,CCNCc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)ccc1OC.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)ccc1OC)C(=O)C(F)(F)F -US20030109527A1,2,NCC1CC1.O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)Cl)c1Cl>>O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)NCC2CC2)c1Cl -US06451834B1,1,CC(C)(C)OC(=O)NN.O=C1CCc2ccccc21>>CC(C)(C)OC(=O)NN=C1CCc2ccccc21 -US05354867,8,CCCc1nc(I)c(CO)[nH]1>>CCCc1nc(I)c(C=O)[nH]1 -US20090176774A1,9,COc1cc2nccc(C(O)c3ccc4cc(Br)ccc4c3)c2cc1OC>>COc1cc2nccc(Cc3ccc4cc(Br)ccc4c3)c2cc1OC -US20090075980A1,9,CCOC(=O)c1cc(CC)n(C)n1.[NH4+]>>CCc1cc(C(N)=O)nn1C -US20050075334A1,4,CCOC(=O)CSC.Nc1cc([N+](=O)[O-])ccc1F>>CSC1C(=O)Nc2c(F)ccc([N+](=O)[O-])c21 -US20140018345A1,1,CS(=O)(=O)c1ccc(CBr)cc1.Cc1c(Br)cn2c(=O)[nH]nc2c1-c1cccc(C(F)(F)F)c1>>Cc1c(Br)cn2c(=O)n(Cc3ccc(S(C)(=O)=O)cc3)nc2c1-c1cccc(C(F)(F)F)c1 -US08158622B2,2,NC(=O)C1CCCCN1.O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)O)c1cc2cc(Cl)ncc2[nH]1>>NC(=O)C1CCCCN1C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)c1cc2cc(Cl)ncc2[nH]1 -US07183298B2,1,NO.O=C(Cl)C=Cc1ccc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)cc1>>O=C(/C=C/c1ccc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)cc1)NO -US20050209254A1,1,CC(C)(C)OC(=O)NCCCN.CN(C)C(=O)C(Br)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1>>CN(C)C(=O)C(NCCCNC(=O)OC(C)(C)C)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1 -US20140121200A1,6,CC(C)(C)OC(=O)N1CC[C@@H](NC(N)=O)C1>>NC(=O)N[C@@H]1CCNC1 -US08071592B2,6,O=C(NC[C@H]1CN(CCn2c(=O)ccc3ncc(F)cc32)C[C@H]1O)OCc1ccccc1>>NC[C@H]1CN(CCn2c(=O)ccc3ncc(F)cc32)C[C@H]1O -US20140200344A1,1,N#CCCl.O=Cc1ccc(O)cc1>>N#CCOc1ccc(C=O)cc1 -US05371086,9,NN.O=[N+]([O-])c1ccc(Cl)nc1>>NNc1ccc([N+](=O)[O-])cn1 -US20070010670A1,2,O=C(Cl)c1cc(Cl)c(O)c(Cl)c1.O=[N+]([O-])c1ccc2c(c1)NCCO2>>O=C(c1cc(Cl)c(O)c(Cl)c1)N1CCOc2ccc([N+](=O)[O-])cc21 -US20090181967A1,2,Fc1ccc(N2CCNCC2)c(F)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCN(c2ccc(F)cc2F)CC1 -US20070072847A1,2,CN(C)C(=O)CO.Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(CC(=O)O)CC3)CC2)cc(C)c1O>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(CC(=O)OCC(=O)N(C)C)CC3)CC2)cc(C)c1O -US20150238558A1,2,CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)C.COC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)OC)cc1)C(=O)[C@@H]1Cc2ccccc2CN1>>COC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)OC)cc1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C -US05817599,1,CCCCCCCCCCCCCCCCCCCCC(O)=S.NCCN1CCOCC1>>CCCCCCCCCCCCCCCCCCCCC(=S)NCCN1CCOCC1 -US09133168B2,2,O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1.c1ccc2c(c1)NCC21CCOCC1>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CC2(CCOCC2)c2ccccc21 -US20100093705A1,3,C=CC(=O)N(C)Cc1cccc(OC)c1OCC(C)C.O=C1CNCc2cc(Br)cnc2N1>>COc1cccc(CN(C)C(=O)/C=C/c2cnc3c(c2)CNCC(=O)N3)c1OCC(C)C -US08476255B2,3,O=C(O)Cc1ccc(F)cc1.O=Cc1ccc(F)c(F)c1>>O=C(O)C(=Cc1ccc(F)c(F)c1)c1ccc(F)cc1 -US20040254156A1,3,COC(=O)Cc1ccc(C=O)cc1.N#CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)Cc1ccc(C=CC#N)cc1 -US20150183804A1,3,Brc1cnc(OCC2CC2)nc1.C=C(OCC)[Sn](CCCC)(CCCC)CCCC>>C=C(OCC)c1cnc(OCC2CC2)nc1 -US20110021493A1,1,CCOC(=O)N1Cc2sc3ncnc(Cl)c3c2C1.Nc1ccc(Cl)c(Cl)c1>>CCOC(=O)N1Cc2sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3c2C1 -US07645781B2,1,CCI.O=c1[nH]c2ccc([N+](=O)[O-])cc2s1>>CCn1c(=O)sc2cc([N+](=O)[O-])ccc21 -US07138425B2,3,COc1ccc([N+](=O)[O-])cc1-c1nc2cc(Br)ccc2o1.COc1cccc(B(O)O)c1>>COc1cccc(-c2ccc3oc(-c4cc([N+](=O)[O-])ccc4OC)nc3c2)c1 -US05643931,7,NC(=O)N(Cc1ccc([N+](=O)[O-])cc1)OCc1ccccc1>>NC(=O)N(Cc1ccc(N)cc1)OCc1ccccc1 -US20050137202A1,2,CSc1cnc(N)c(I)c1.O=S(=O)(Cl)c1ccccc1>>CSc1cnc(NS(=O)(=O)c2ccccc2)c(I)c1 -US20100234316A1,6,CC(C)(C)OC(=O)n1ccc2cc(O[Si](C)(C)C(C)(C)C)ccc21>>CC(C)(C)OC(=O)n1ccc2cc(O)ccc21 -US20040248872A1,6,COC(=O)c1ccc2nsnc2c1>>O=C(O)c1ccc2nsnc2c1 -US07265149B2,7,CCOC(=O)c1c(C)c(-c2ccc(Cl)cc2)nn1C>>Cc1c(-c2ccc(Cl)cc2)nn(C)c1CO -US20020052322A1,2,COC(=O)C(N)c1cc2cc(Cl)ccc2s1.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>COC(=O)C(NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1)c1cc2cc(Cl)ccc2s1 -US04150131,1,COC(=O)Nc1cc(Cl)nc(NC(=O)OC)[n+]1[O-].OC1CCCNC1>>COC(=O)Nc1cc(N2CCCC(O)C2)nc(NC(=O)OC)[n+]1[O-] -US20030144507A1,7,CC(=O)NCCc1cccc([N+](=O)[O-])c1>>CC(=O)NCCc1cccc(N)c1 -US08518972B2,1,C1COCCN1.CS(=O)(=O)OCc1cc(COc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)on1>>O=C1CCC(N2Cc3c(OCc4cc(CN5CCOCC5)no4)cccc3C2=O)C(=O)N1 -US20120295897A1,6,COC(=O)c1coc(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)n1>>O=C(O)c1coc(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)n1 -US20100286161A1,9,Cc1cc(C)n(-c2cnc(C=O)c(Nc3ccc(Cl)cc3)n2)n1.NO>>Cc1cc(C)n(-c2cnc(C=NO)c(Nc3ccc(Cl)cc3)n2)n1 -US06380218B1,2,CNOC.O=C(O)CCc1ccc(F)cc1>>CON(C)C(=O)CCc1ccc(F)cc1 -US20130184313A1,1,CN1CCC[C@H]1COc1cncc(-c2cc(CCCO)no2)c1.Oc1ccccc1>>CN1CCC[C@H]1COc1cncc(-c2cc(CCCOc3ccccc3)no2)c1 -US20120035214A1,9,COC(=O)c1ccccc1C=O.NO>>COC(=O)c1ccccc1C=NO -US08288419B2,2,CC(F)(F)c1ccc(Cn2cc(N)cn2)o1.Cc1nc(C(=O)O)c(-c2ccccc2)o1>>Cc1nc(C(=O)Nc2cnn(Cc3ccc(C(C)(F)F)o3)c2)c(-c2ccccc2)o1 -US20090258866A1,3,C=CCCC(O[Si](C(C)C)(C(C)C)C(C)C)c1ncccc1C=C>>CC(C)[Si](OC1CCC=Cc2cccnc21)(C(C)C)C(C)C -US20060035870A1,2,COC(=O)[C@@H](Cc1ccccc1)N=C=O.OCc1ccc(COc2ccccc2)cc1>>COC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccc(COc2ccccc2)cc1 -US07994218B2,6,COc1ccc(CO[C@@H](C(=O)O[C@@H](C)c2ccccc2)C(C)(C)COS(=O)(=O)CCCCl)cc1>>C[C@H](OC(=O)[C@H](O)C(C)(C)COS(=O)(=O)CCCCl)c1ccccc1 -US05132312,6,COC(=O)CC(O)CC(O)/C=C/C1=C(c2ccc(F)c(C)c2)CC2(CC1(C)C)SCCCS2>>Cc1cc(C2=C(/C=C/C(O)CC(O)CC(=O)O)C(C)(C)CC3(C2)SCCCS3)ccc1F -US20150246922A1,3,CC1CCNC(=O)c2cc3cc(F)cc(Br)c3n21.OB(O)c1ccccc1>>CC1CCNC(=O)c2cc3cc(F)cc(-c4ccccc4)c3n21 -US20100160379A1,8,OCc1ccc(CCC2CCCO2)cc1>>O=Cc1ccc(CCC2CCCO2)cc1 -US06265434B1,1,COc1ccc(CCl)cc1.O=C(O)[C@@H](O)CC1CCC1>>COc1ccc(COC(=O)[C@@H](O)CC2CCC2)cc1 -US20150225411A1,2,NCC(F)F.O=C(O)c1cc(F)c(Cl)cc1F>>O=C(NCC(F)F)c1cc(F)c(Cl)cc1F -US20040143009A1,1,CCN.O=CC=Cc1ccccc1>>CCNCC=Cc1ccccc1 -US04782176,1,BrCCOCCOCCOCCBr.CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1O>>CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1OCCOCCOCCOCCBr -US20130217666A1,3,C#CC(C)(O)C(F)(F)F.NC(=O)c1cn2c(n1)-c1cc(Br)c(F)cc1OCC2>>CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)C(F)(F)F -US20040102436A1,1,CC(C)=O.NCCCCO>>CC(C)NCCCCO -US20070072902A1,2,C1COCCN1.CCOc1cc(C(CC(=O)O)N2Cc3cccc(NC(C)=O)c3C2=O)ccc1OC(F)F>>CCOc1cc(C(CC(=O)N2CCOCC2)N2Cc3cccc(NC(C)=O)c3C2=O)ccc1OC(F)F -US20140296532A1,3,Brc1cccc(I)c1.C#Cc1ccccc1>>Brc1cccc(C#Cc2ccccc2)c1 -US07501538B2,2,COC(=O)[C@@H](N)Cc1ccc(-c2ccc(Oc3ccccc3)cc2)cc1.Nc1ccc(Cl)cc1C(=O)O>>COC(=O)[C@H](Cc1ccc(-c2ccc(Oc3ccccc3)cc2)cc1)NC(=O)c1cc(Cl)ccc1N -US20030069421A1,7,COc1ccc2c(c1)C(=O)C(=O)N2>>COc1ccc2c(c1)CC(=O)N2 -US07335660B2,7,O=C(O)CC1OCc2cc(Cl)ccc21>>OCCC1OCc2cc(Cl)ccc21 -US20060154915A1,6,CC(C)(C)OC(=O)NCC1CCC(C(=O)NC(Cc2ccccc2)c2cccc(-c3ccc(N)nc3)c2)CC1>>NCC1CCC(C(=O)NC(Cc2ccccc2)c2cccc(-c3ccc(N)nc3)c2)CC1 -US20070003539A1,2,COC(=O)Nc1ccc(S(=O)(=O)C(C)C)c(CN)c1.COc1ccc(C(Nc2cccc(C(N)=O)c2)C(=O)O)cc1OC>>COC(=O)Nc1ccc(S(=O)(=O)C(C)C)c(CNC(=O)C(Nc2cccc(C(N)=O)c2)c2ccc(OC)c(OC)c2)c1 -US20140371455A1,1,COC(=O)N[C@H](C(=O)N1CC2(C[C@H]1C(=O)O)CC(F)(F)C2)C(C)C.COC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)OCC(=O)c1ccc(-c2ccc(C(=O)CBr)cc2)cc1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)OCC(=O)c1ccc(-c2ccc(C(=O)COC(=O)[C@@H]3CC4(CN3C(=O)[C@@H](NC(=O)OC)C(C)C)CC(F)(F)C4)cc2)cc1)C(C)C -US20090221567A1,6,CC(C)(C)OC(=O)N[C@H]1CCCC[C@@H]1CN=[N+]=[N-]>>[N-]=[N+]=NC[C@H]1CCCC[C@@H]1N -US20100286120A1,6,CC(C)[C@@H](C)Oc1ccc2c(n1)OCCN(C(=O)OC(C)(C)C)C2>>CC(C)[C@@H](C)Oc1ccc2c(n1)OCCNC2 -US05091387,7,Cc1ccc(S(=O)(=O)N2CCC3(C=Cc4ccccc43)CC2)cc1>>Cc1ccc(S(=O)(=O)N2CCC3(CCc4ccccc43)CC2)cc1 -US20070254935A1,3,CON(C)C(=O)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1.C[Mg+]>>CC(=O)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1 -US06100258,6,CCN(Cc1cc(Br)ccc1O)c1ccc(C(=O)OC)cn1>>CCN(Cc1cc(Br)ccc1O)c1ccc(C(=O)O)cn1 -US20080194549A1,1,CCc1ccc(C(=O)OC)cc1O.OCCCBr>>CCc1ccc(C(=O)OC)cc1OCCCO -US07683091B2,7,CC(C)(C)c1ccc(Cn2ccc3cc([N+](=O)[O-])ccc32)cc1>>CC(C)(C)c1ccc(Cn2ccc3cc(N)ccc32)cc1 -US06448442B1,6,CC(=O)OC(CCCCl)C(=O)OCc1ccccc1>>CC(=O)OC(CCCCl)C(=O)O -US20090036450A1,9,CCOC(=O)c1oc(C)nc1-c1ccc(F)cc1.N>>Cc1nc(-c2ccc(F)cc2)c(C(N)=O)o1 -US06051712,1,C=[N+]=[N-].CC(C)(C)OC(=O)N1CCC(c2ccc(CC(=O)O)cc2)C(OCc2ccc3ccccc3c2)C1>>COC(=O)Cc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc3ccccc3c2)cc1 -US20140142085A1,2,COc1cccc(CC(=O)O)c1.NC(=O)c1cccc(-c2cccnc2[C@@H](N)Cc2cc(F)cc(F)c2)c1>>COc1cccc(CC(=O)N[C@@H](Cc2cc(F)cc(F)c2)c2ncccc2-c2cccc(C(N)=O)c2)c1 -US20090036422A1,2,COc1ccccc1C(NC(=O)OC(C)(C)C)C(=O)O.Cc1ccc(NCCc2ccc(C(F)(F)F)cc2)cc1C>>COc1ccccc1C(NC(=O)OC(C)(C)C)C(=O)N(CCc1ccc(C(F)(F)F)cc1)c1ccc(C)c(C)c1 -US04699949,2,C1COCCN1.Cc1ccc(S(=O)(=O)OC(C)C(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC(C)C(=O)N2CCOCC2)cc1 -US05843942,1,CCOC(=O)c1ccc(N)cc1.O=Cc1nccnc1OCc1ccccc1>>CCOC(=O)c1ccc(NCc2nccnc2OCc2ccccc2)cc1 -US06114390,2,CNS(=O)(=O)Cc1ccc(CN)cc1.NC(=N[N+](=O)[O-])NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)O>>CNS(=O)(=O)Cc1ccc(CNC(=O)[C@@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(c2ccccc2)c2ccccc2)cc1 -US07470722B2,2,CC(=O)c1ccc(S(=O)(=O)Cl)cc1.NCc1cccc2ccccc12>>CC(=O)c1ccc(S(=O)(=O)NCc2cccc3ccccc23)cc1 -US20100087424A1,1,N[C@@H]1CCN(C[C@@H]2COc3c(F)cnc4ccc(=O)n2c34)C[C@@H]1O.O=Cc1cc2c(cn1)OCCC2>>O=c1ccc2ncc(F)c3c2n1[C@H](CN1CC[C@@H](NCc2cc4c(cn2)OCCC4)[C@@H](O)C1)CO3 -US20090325930A1,6,COc1ccc2cc(-c3ccccc3Nc3ccc(OCCN4CCCCC4)c(F)c3)ccc2c1>>Oc1ccc2cc(-c3ccccc3Nc3ccc(OCCN4CCCCC4)c(F)c3)ccc2c1 -US20110077235A1,3,Cc1cc2nc(NC(=O)c3ccc(C(C)(C)O)cc3)cc(Cl)n2n1.OB(O)c1ccccc1>>Cc1cc2nc(NC(=O)c3ccc(C(C)(C)O)cc3)cc(-c3ccccc3)n2n1 -US06358971B1,3,CON(C)C(=O)c1ccc2nc(N)c(-c3ccccc3)n2c1.Fc1cccc(Br)c1>>Nc1nc2ccc(C(=O)c3cccc(F)c3)cn2c1-c1ccccc1 -US20090215778A1,1,COc1ccc(-c2nc3c(C(=O)N4CCNC[C@H]4C)cnn3c(C(F)(F)F)c2C)cc1.C[C@@H](O)c1ccccc1C#N>>COc1ccc(-c2nc3c(C(=O)N4CCN([C@@H](C)c5ccccc5C#N)C[C@H]4C)cnn3c(C(F)(F)F)c2C)cc1 -US06177429B1,2,CC(C)(C)C1CCN(CCCN)CC1.COC(=O)C1=C(C)NC(C)=C(C(=O)OC)N1c1cccc(N=C=S)c1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC)N1c1cccc(NC(=S)NCCCN2CCC(C(C)(C)C)CC2)c1 -US03987116,2,CCO.COc1cccc2cc(C=CC(=O)O)ccc12>>CCOC(=O)C=Cc1ccc2c(OC)cccc2c1 -US04820834,2,CCN(CC)C(=O)CN1C(=O)C(N)N=C(c2ccccc2)c2ccccc21.O=C=Nc1ccccc1Cl>>CCN(CC)C(=O)CN1C(=O)C(NC(=O)Nc2ccccc2Cl)N=C(c2ccccc2)c2ccccc21 -US20060189601A1,1,COc1ccc2nccc(N3CCN(CCN)CC3)c2c1.O=Cc1ccc2c(n1)NC(=O)CO2>>COc1ccc2nccc(N3CCN(CCNCc4ccc5c(n4)NC(=O)CO5)CC3)c2c1 -US20090149483A1,1,Clc1ccccc1CBr.Cn1c(=O)c2[nH]c(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)cc2n(C)c1=O>>Cn1c(=O)c2c(cc(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)n2Cc2ccccc2Cl)n(C)c1=O -US05491167,1,CCC(Oc1ccc(C(C)(C)C)cc1)C(=O)O.C[C@H]1C=CC2=C[C@@H](C(C)(C)C)C[C@H](O)[C@@H]2[C@@]1(CC[C@@H]1C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O1)O[SiH](C)C>>CCC(Oc1ccc(C(C)(C)C)cc1)C(=O)O[C@H]1C[C@H](C(C)(C)C)C=C2C=C[C@H](C)[C@](CC[C@@H]3C[C@H](C(C)(C)C)C(O[SiH](C)C)C(=O)O3)(O[SiH](C)C)[C@H]21 -US20090281046A1,2,CCOC(=O)C1[C@@H]2[C@@H](O)[C@@H]3OC(C)(C)OC[C@H]3O[C@H]12.NS(=O)(=O)Cl>>CCOC(=O)C1[C@@H]2[C@@H](OS(N)(=O)=O)[C@@H]3OC(C)(C)OC[C@H]3O[C@H]12 -US08420654B2,3,C=COCC.CCOC(=O)C(=O)Cl>>CCO/C=C/C(=O)C(=O)OCC -US20080039437A1,1,CCOC(=O)c1cc(C#N)c(Cl)nc1C(F)F.O=C(O)C1CNC1>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1C(F)F -US20080194565A1,6,CC(C)(C)OC(=O)C(CCn1nnc2ccccc2c1=O)C(O)CCc1ccc(-c2ccccc2)cc1>>O=C(O)C(CCn1nnc2ccccc2c1=O)C(O)CCc1ccc(-c2ccccc2)cc1 -US08501750B2,1,N#Cc1ccccc1-c1ccc(Cn2c(=O)[nH]c(=O)c3cc(CC(F)(F)F)sc32)cc1.O=C(CBr)c1ccc(F)cc1>>N#Cc1ccccc1-c1ccc(Cn2c(=O)n(CC(=O)c3ccc(F)cc3)c(=O)c3cc(CC(F)(F)F)sc32)cc1 -US04589910,2,CN=C=O.Nc1ccc(Oc2ccc3sncc3c2)c(C(F)(F)F)c1>>CNC(=O)Nc1ccc(Oc2ccc3sncc3c2)c(C(F)(F)F)c1 -US20140213586A1,1,COc1cncc(N)c1.O=Cc1cc2ccccn2n1>>COc1cncc(N=Cc2cc3ccccn3n2)c1 -US20080139562A1,1,CN1CCNCC1.Nc1ncc(Br)s1>>CN1CCN(c2cnc(N)s2)CC1 -US08598154B2,1,C1CCNC1.CCOC[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(Cl)nc1)C2>>CCOC[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCCC3)nc1)C2 -US08383822B2,7,Cc1cc([N+](=O)[O-])cc(C)c1-n1cccc(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1=O>>Cc1cc(N)cc(C)c1-n1cccc(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1=O -US20140038919A1,6,CC(C)(C)OC(=O)NNC(=O)CCCN(c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1)S(C)(=O)=O>>CS(=O)(=O)N(CCCC(=O)NN)c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1 -US20070225349A1,3,CON(C)C(=O)c1cccc(F)c1F.COc1ccc([Mg+])c(OC)c1>>COc1ccc(C(=O)c2cccc(F)c2F)c(OC)c1 -US07727997B2,2,CCc1cccc(CNC[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)c1.CS(=O)(=O)CC1CCC(C(=O)O)CC1>>CCc1cccc(CNC[C@@H](O)[C@H](Cc2cc(F)cc(F)c2)NC(=O)C2CCC(CS(C)(=O)=O)CC2)c1 -US20150018332A1,7,N#CC1(F)CN(C(c2ccccc2)c2ccccc2)C1>>NCC1(F)CN(C(c2ccccc2)c2ccccc2)C1 -US20100249124A1,1,CC(c1ccc(O)cc1Cl)C(O)(c1ccc2c(c1)n(C)c(=O)n2C)C(F)(F)F.N#Cc1ccc(F)c(F)c1>>CC(c1ccc(Oc2ccc(C#N)cc2F)cc1Cl)C(O)(c1ccc2c(c1)n(C)c(=O)n2C)C(F)(F)F -US20150094328A1,1,COc1ccc(CCl)cc1C.Cc1ccnc2c(C(=O)N[C@H]3CCCC[C@@H]3O)c[nH]c12>>COc1ccc(Cn2cc(C(=O)N[C@H]3CCCC[C@@H]3O)c3nccc(C)c32)cc1C -US20080051416A1,2,C[C@H](O)CN.Cc1c(F)cc(C(=O)O)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O>>Cc1c(F)cc(C(=O)NC[C@H](C)O)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O -US05763191,1,CC(=O)Cl.CC(S)C(=O)O>>CC(=O)SC(C)C(=O)O -US20150175602A1,2,CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CCNC2.O=C(Cl)N1CCCC1>>CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CCN(C(=O)N1CCCC1)C2 -US06605635B1,2,Nc1ccc(O)cc1.O=S(=O)(Cl)c1cccc2ccccc12>>O=S(=O)(Nc1ccc(O)cc1)c1cccc2ccccc12 -US20020019387A1,6,COC(=O)C[C@@H]1Cc2ccc(OCCCNc3ccccn3)cc2CN(Cc2ccc(F)c(F)c2F)C1=O>>O=C(O)C[C@@H]1Cc2ccc(OCCCNc3ccccn3)cc2CN(Cc2ccc(F)c(F)c2F)C1=O -US20030216410A1,3,O=C1Cc2cc(Br)ccc2N1.OB(O)c1ccccc1>>O=C1Cc2cc(-c3ccccc3)ccc2N1 -US20110212956A1,2,CC1NCCc2cccc(F)c21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2c(F)cccc2CCN1C(=O)c1cc2ncc(Cl)cn2n1 -US05571810,4,CS(=O)(=O)c1ccc(-c2cc(C#N)sc2-c2ccc(F)cc2)cc1.[N-]=[N+]=[N-]>>CS(=O)(=O)c1ccc(-c2cc(-c3nnn[nH]3)sc2-c2ccc(F)cc2)cc1 -US20140309227A1,1,COC(=O)CC(=O)C(=O)OC.Cc1cccc(N)c1F>>COC(=O)C/C(=N\c1cccc(C)c1F)C(=O)OC -US20020177589A1,1,CC1CCCCN1.CS(=O)(=O)OCCc1cc2cc(-c3ccc(C(=O)N4CCOCC4)cc3)ccc2o1>>CC1CCCCN1CCc1cc2cc(-c3ccc(C(=O)N4CCOCC4)cc3)ccc2o1 -US20110263571A1,1,CC1(C)CNC(=O)O1.Cc1cc(C)c(N2CCN(C(=O)c3ccc(I)cc3)CC2)nc1C>>Cc1cc(C)c(N2CCN(C(=O)c3ccc(N4CC(C)(C)OC4=O)cc3)CC2)nc1C -US07304082B2,2,NC(N)=S.S=C=Nc1ccccc1>>NC(=S)NC(=S)Nc1ccccc1 -US04933453,1,CC1SCN(CCCCBr)C1=O.c1ccc2c(N3CCNCC3)nsc2c1>>CC1SCN(CCCCN2CCN(c3nsc4ccccc34)CC2)C1=O -US08871361B2,1,CC(C)c1cccc(C(C)C)c1-n1ccnc1-c1cccc(Br)c1.Cc1cc(O)cc(-c2nccn2-c2c(C(C)C)cccc2C(C)C)c1>>Cc1cc(Oc2cccc(-c3nccn3-c3c(C(C)C)cccc3C(C)C)c2)cc(-c2nccn2-c2c(C(C)C)cccc2C(C)C)c1 -US20020165259A1,7,CC(=O)Nc1ncc(/C=C/c2ncc(C(C)(C)C)o2)s1>>CC(=O)Nc1ncc(CCc2ncc(C(C)(C)C)o2)s1 -US08618289B2,6,COc1cc(OC)c2c(=O)[nH]cnc2c1>>COc1cc(O)c2c(=O)[nH]cnc2c1 -US06924300B2,9,CCOC(=O)CCCC(=O)c1ccccc1.NO>>CCOC(=O)CCC/C(=N\O)c1ccccc1 -US06174898B1,6,CCOC(=O)[C@@H]1CCCN(CCOCC=C(c2ccccc2)c2ccccc2C)C1>>Cc1ccccc1C(=CCOCCN1CCC[C@@H](C(=O)O)C1)c1ccccc1 -US20090176824A1,6,CC(C)(C)[Si](C)(C)O[C@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1CN=[N+]=[N-]>>[N-]=[N+]=NC[C@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1O -US20140213448A1,8,C#CCN(C(=O)C(C)SC)c1cn(-c2cccnc2)nc1Cl.OO>>C#CCN(C(=O)C(C)S(C)=O)c1cn(-c2cccnc2)nc1Cl -US20090247567A1,3,CC(C)n1c(-c2cc3c(s2)-c2ccc(Br)cc2OCC3)n[nH]c1=O.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC(C)n1c(-c2cc3c(s2)-c2ccc(-c4cn[nH]c4)cc2OCC3)n[nH]c1=O -US20120309796A1,2,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2N.O=S(=O)(Cl)c1cc(Br)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1cc(Br)cc(C(F)(F)F)c1 -US20050113370A1,1,CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(N)cc21.Clc1ccccc1Br>>CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(Nc3ccccc3Cl)cc21 -US05308843,3,CCOC(=O)c1cn2c3c(c(Br)c(F)cc3c1=O)OC[C@@H]2C.C[Sn](C)(C)c1ccncc1>>CCOC(=O)c1cn2c3c(c(-c4ccncc4)c(F)cc3c1=O)OC[C@@H]2C -US07157604B2,6,CCCCC12CCC(=O)C=C1c1ccc(NC(C)=O)cc1C2>>CCCCC12CCC(=O)C=C1c1ccc(N)cc1C2 -US05610161,9,CCOC(=O)C1CCNC2(CCCCC2)C1=O>>O=C1CCCNC12CCCCC2 -US20110092461A1,6,Cc1cccc(CN2C(=O)c3ccccc3C2=O)n1>>Cc1cccc(CN)n1 -US03997557,4,CN(C)CCCN.O=C(CC1CCCCCC1=O)c1ccc(Br)cc1>>CN(C)CCCn1c(-c2ccc(Br)cc2)cc2c1CCCCC2 -US04331670,1,CCO.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1Nc1ncc(C(F)(F)F)cc1Cl>>CCOc1c(C(F)(F)F)cc([N+](=O)[O-])c(Nc2ncc(C(F)(F)F)cc2Cl)c1[N+](=O)[O-] -US07772253B2,2,CCOc1cc(CN2CCC(N)CC2)ccc1Cl.O=C(Cl)c1cccc2ccccc12>>CCOc1cc(CN2CCC(NC(=O)c3cccc4ccccc34)CC2)ccc1Cl -US20120115869A1,3,CCC(=O)N(Cc1cccc(I)c1)c1cccc(C#N)c1.OB(O)c1ccncc1>>CCC(=O)N(Cc1cccc(-c2ccncc2)c1)c1cccc(C#N)c1 -US06211373B1,7,O=C(Nc1ccc([N+](=O)[O-])cc1O)Nc1ccccc1I>>Nc1ccc(NC(=O)Nc2ccccc2I)c(O)c1 -US05149698,6,BrCCCCCOCCCc1nc2ccccc2n1Cc1ccccc1>>BrCCCCCOCCCc1nc2ccccc2[nH]1 -US20150203479A1,7,CC(=O)c1cc(C(=O)NC[C@@H](C)n2ccc(-c3ccc(C#N)c(C(F)(F)F)c3)n2)[nH]n1>>CC(O)c1cc(C(=O)NC[C@@H](C)n2ccc(-c3ccc(C#N)c(C(F)(F)F)c3)n2)[nH]n1 -US20050182093A1,2,C[C@H](N)C1CCCCC1.Cc1c(-c2ccccc2)nc2cc3c(cc2c1C(=O)O)OCCO3>>Cc1c(-c2ccccc2)nc2cc3c(cc2c1C(=O)N[C@@H](C)C1CCCCC1)OCCO3 -US20100160308A1,1,COC(OC)c1ccc([N+](=O)[O-])c(F)c1.NC(=O)c1sc(N)nc1-c1ccc(C(F)(F)F)cc1>>COC(OC)c1ccc([N+](=O)[O-])c(Nc2nc(-c3ccc(C(F)(F)F)cc3)c(C(N)=O)s2)c1 -US07253192B2,1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.C[Si](C)(C)C#CCC1(CI)CC1>>CCOC(=O)C(C)(C)Oc1ccc(OCC2(CC#C[Si](C)(C)C)CC2)cc1C -US20100286211A1,1,Cc1cc(C)[nH]n1.Clc1ncc(Br)cn1>>Cc1cc(C)n(-c2ncc(Br)cn2)n1 -US09045420B2,6,COC(=O)c1ccc(N2CCN(CC3=C(c4ccc(Cl)cc4)CCC(O)C3)CC2)cc1Oc1ccc2[nH]ccc2c1>>O=C(O)c1ccc(N2CCN(CC3=C(c4ccc(Cl)cc4)CCC(O)C3)CC2)cc1Oc1ccc2[nH]ccc2c1 -US20150094306A1,1,CC(C)(C)[S@](N)=O.Cc1cc(C=O)ncc1OCc1ccc(F)cc1>>Cc1cc(/C=N/[S@](=O)C(C)(C)C)ncc1OCc1ccc(F)cc1 -US20050267104A1,6,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)OC(=O)N(C[C@H]1CN(c2ccc(C3CCS(=O)(=O)CC3)c(F)c2)C(=O)O1)C(C)=O>>CC[C@H](C)[C@H](N)C(=O)OC(C)OC(=O)N(C[C@H]1CN(c2ccc(C3CCS(=O)(=O)CC3)c(F)c2)C(=O)O1)C(C)=O -US20100144760A1,7,COC(=O)[C@@H]1CC=CCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=CC[C@H]1CO -US20130040930A1,1,CCOC(=O)c1ccc(N)cc1.O=[N+]([O-])c1cccnc1Cl>>CCOC(=O)c1ccc(Nc2ncccc2[N+](=O)[O-])cc1 -US20080167301A1,6,CCOc1cc2c(cc1OC)C(c1ccc(OC)nc1OC)=NC1CCC(OC(C)=O)CC21>>CCOc1cc2c(cc1OC)C(c1ccc(OC)nc1OC)=NC1CCC(O)CC21 -US06117873,9,COc1nc2cc(F)cc(CBr)c2nc1OC.[N-]=[N+]=[N-]>>COc1nc2cc(F)cc(CN=[N+]=[N-])c2nc1OC -US20090312310A1,6,CC(C)C1=C(C(=O)N(CCO[Si](C)(C)C(C)(C)C)C(C)C)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21>>CC(C)C1=C(C(=O)N(CCO)C(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21 -US20120022030A1,1,C1COCCN1.N#Cc1ccc(F)c(Cl)c1>>N#Cc1ccc(N2CCOCC2)c(Cl)c1 -US04473580,2,CC(C)C(=NSN(C)C(=O)F)Sc1ccccc1.CC1(C)Cc2cccc(O)c2O1>>CC(C)C(=NSN(C)C(=O)Oc1cccc2c1OC(C)(C)C2)Sc1ccccc1 -US04837333,4,C=CCCCc1ccc(OC)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(CCCC2CO2)cc1 -US04337256,2,CCCCCCC(=O)Cl.NCCc1ccccc1Cl>>CCCCCCC(=O)NCCc1ccccc1Cl -US07179823B1,6,CCOC(=O)CCc1cn(Cc2ccc3cc(OCc4cccnc4C)ccc3c2)cc1-c1ccccc1>>Cc1ncccc1COc1ccc2cc(Cn3cc(CCC(=O)O)c(-c4ccccc4)c3)ccc2c1 -US20090233929A1,3,Brc1ncccn1.CON(C)C(=O)c1cn(-c2cccc(-c3ccccc3C#N)c2)cn1>>N#Cc1ccccc1-c1cccc(-n2cnc(C(=O)c3ncccn3)c2)c1 -US20150266857A1,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)c2ccc(F)cc21.O=S1(=O)NCc2cc(Br)ccc21>>CC(C)(C)OC(=O)n1cc(-c2ccc3c(c2)CNS3(=O)=O)c2ccc(F)cc21 -US20090221555A1,2,CS(=O)(=O)Cl.O=[N+]([O-])c1ccc2c(c1)CCNCC2>>CS(=O)(=O)N1CCc2ccc([N+](=O)[O-])cc2CC1 -US20090192136A1,1,CC(C)(C)OC(=O)N1CCNCC1.Cc1ccc(Br)c(F)c1>>Cc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)c(F)c1 -US08003662B2,2,CC1(C(=O)O)CCN(c2ccc(F)cc2)C1=O.CN1CCN(CC#Cc2cc3nccc(Oc4ccc(N)cc4F)c3s2)CC1>>CN1CCN(CC#Cc2cc3nccc(Oc4ccc(NC(=O)C5(C)CCN(c6ccc(F)cc6)C5=O)cc4F)c3s2)CC1 -US04211871,8,CC(=O)Nc1cccc(Br)n1.CC(=O)OO>>CC(=O)Nc1cccc(Br)[n+]1[O-] -US20140023614A1,6,CC(C)(C)OC(=O)N1CCC(c2ccnc3cnc4[nH]ccc4c23)CC1>>c1cc(C2CCNCC2)c2c(cnc3[nH]ccc32)n1 -US07449490B2,3,CCOC(=O)CC#N.CCc1ccc(C(C)=O)cc1>>CCOC(=O)C(C#N)=C(C)c1ccc(CC)cc1 -US06982348B2,6,CCOC(=O)C(Cc1ccc(C(F)(F)F)o1)C(O)c1ccc(F)cc1>>O=C(O)C(Cc1ccc(C(F)(F)F)o1)C(O)c1ccc(F)cc1 -US20050192347A1,7,CCOC(=O)C(C)(CCCCCBr)c1ccccc1>>CC(CO)(CCCCCBr)c1ccccc1 -US20110257151A1,2,CC1(C)Cc2cc(Cl)cc(C(=O)O)c2NC1c1cccc(N2CCOCC2)c1.NS(=O)(=O)C1CC1>>CC1(C)Cc2cc(Cl)cc(C(=O)NS(=O)(=O)C3CC3)c2NC1c1cccc(N2CCOCC2)c1 -US05580872,3,C[Mg+].[O-][n+]1c(F)c(F)c(F)c(F)c1F>>Cc1c(F)c(F)c(F)c(F)[n+]1[O-] -US04895840,1,CCN(CC)CCN.O=S(CCCl)c1ccccc1>>CCN(CC)CCNCCS(=O)c1ccccc1 -US20080194617A1,2,CCOC(=O)CNS(=O)(=O)NCc1ccc(OC)cc1>>COc1ccc(CN2C(=O)CNS2(=O)=O)cc1 -US08658636B2,1,CS(=O)(=O)c1ccc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(=O)CC3)c(C(=O)N[C@H](c3ccccc3)C(F)(F)F)c2c1.C[C@H]1CCCN1>>C[C@@H]1CCCN1C1CCN(Cc2c(-c3cccc(C(F)(F)F)c3)nc3ccc(S(C)(=O)=O)cc3c2C(=O)N[C@H](c2ccccc2)C(F)(F)F)CC1 -US05480857,9,CSc1ncccc1C(=O)C(C(=O)OC(C)(C)C)C(=O)C1CC1>>CSc1ncccc1C(=O)CC(=O)C1CC1 -US20110306618A1,6,CCOC(=O)C1CCC(Nc2nccc(-c3cnc4c(OCc5ccccc5)cccn34)n2)CC1>>CCOC(=O)C1CCC(Nc2nccc(-c3cnc4c(O)cccn34)n2)CC1 -US20150218143A1,7,COCCOc1ccc(C(=O)O)cc1>>COCCOc1ccc(CO)cc1 -US20150087585A1,1,C[C@H]1COC(c2ccccn2)CN1.Nc1nc(Cl)ccc1[N+](=O)[O-]>>C[C@H]1COC(c2ccccn2)CN1c1ccc([N+](=O)[O-])c(N)n1 -US20080287434A1,2,CC(NCCCN)c1ccc(Cl)c(Cl)c1.O=C(O)CCc1nc2ccc(N3CCCCC3)nc2s1>>CC(NCCCNC(=O)CCc1nc2ccc(N3CCCCC3)nc2s1)c1ccc(Cl)c(Cl)c1 -US08809380B2,2,Nc1ccccn1.O=C(O)c1ncccc1OC[C@H]1C[C@@H](OCOCc2ccccc2)CN1C(=O)[C@@H]1CC[C@@H](C(F)(F)F)CC1>>O=C(Nc1ccccn1)c1ncccc1OC[C@H]1C[C@@H](OCOCc2ccccc2)CN1C(=O)[C@@H]1CC[C@@H](C(F)(F)F)CC1 -US07423185B2,7,O=C(Oc1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1)c1ccccc1>>O=C(OCc1ccccc1)c1ccc(O)cc1OCc1ccccc1 -US20130324530A1,3,Fc1cccc(CNc2cncc(Br)c2)c1.OB(O)c1ccnc(F)c1>>Fc1cccc(CNc2cncc(-c3ccnc(F)c3)c2)c1 -US20080300242A1,1,CCOc1cc(CCN2CCN(C)CC2)ccc1N.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>CCOc1cc(CCN2CCN(C)CC2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US20030134854A1,1,COCCOCCO.COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccnc(Cl)c3)nc12>>COCCOCCOc1cc(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)ccn1 -US20100256134A1,2,CCS(N)(=O)=O.Cc1ccc(C)c(Nc2c(C(=O)N3CCC4(CC3)COc3ccccc34)cnc3c(C(=O)O)cnn23)c1>>CCS(=O)(=O)NC(=O)c1cnn2c(Nc3cc(C)ccc3C)c(C(=O)N3CCC4(CC3)COc3ccccc34)cnc12 -US20130053381A1,1,CCOC(=O)Cl.Cc1nccn1-c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)(F)F>>CCOC(=O)N(n1c(=O)[nH]c2cc(C(F)(F)F)c(-n3ccnc3C)cc2c1=O)S(C)(=O)=O -US20130331372A1,3,COc1ccc([N+](=O)[O-])cc1B1OCC(C)(C)CO1.C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1nc(N2CCC2)ccc1Br>>COc1ccc([N+](=O)[O-])cc1-c1ccc(N2CCC2)nc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C -US06525001B1,3,Cc1cnc(Cl)nc1Cl.FC(F)(F)c1cccc(CBr)c1>>Cc1cnc(Cl)nc1Cc1cccc(C(F)(F)F)c1 -US20060229363A1,2,CCc1ccc(SCCN)cc1.COC(=O)c1cc(S(=O)(=O)Cl)cc(C)c1C>>CCc1ccc(SCCNS(=O)(=O)c2cc(C)c(C)c(C(=O)OC)c2)cc1 -US20110076291A1,3,CC(C)n1ncnc1-c1nc2c(s1)CCOc1ccc(Br)cc1-2.COc1cncc(B2OC(C)(C)C(C)(C)O2)c1>>COc1cncc(-c2ccc3c(c2)-c2nc(-c4ncnn4C(C)C)sc2CCO3)c1 -US20040214832A1,6,COc1ccccc1COCCCOc1ccc(N2CCN(C(=O)OC(C)(C)C)C[C@@H]2COc2ccc3ccccc3c2)cc1>>COc1ccccc1COCCCOc1ccc(N2CCNC[C@@H]2COc2ccc3ccccc3c2)cc1 -US20110082111A1,2,CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)O)cc3C(F)(F)F)ncc21.CN1CCC(N)CC1>>CN1CCC(NC(=O)c2ccc(Nc3ncc4c(n3)N(C3CCCC3)CC(F)(F)C(=O)N4C)c(C(F)(F)F)c2)CC1 -US20130040930A1,2,Cc1cnc(N2CCNCC2)c(C)c1.O=C(Cl)c1ccc(Br)cc1F>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3F)CC2)c(C)c1 -US05814653,1,CCI.NC1CCc2[nH]c3ccc(OCc4ccccc4)cc3c2C1>>CCNC1CCc2[nH]c3ccc(OCc4ccccc4)cc3c2C1 -US06248894B1,2,CCOCCN.C[Si](C)(C)c1cccc(Cl)c1C(=O)Cl>>CCOCCNC(=O)c1c(Cl)cccc1[Si](C)(C)C -US07781426B2,1,CCNC[C@@H]1CC[C@@H](CC(=O)OCC)CC1.O=Cc1ncccc1F>>CCOC(=O)C[C@@H]1CC[C@@H](CN(CC)c2cccnc2C=O)CC1 -US07148246B2,7,Cc1ccc(C(O[C@@H]2CCC[C@H](C=C3SC(=O)NC3=O)C2)c2cocn2)c(C)c1>>Cc1ccc(C(O[C@@H]2CCC[C@H](CC3SC(=O)NC3=O)C2)c2cocn2)c(C)c1 -US20030083333A1,6,COc1c(NC(=O)Nc2ccc(C(=O)OC(C)(C)C)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)Nc2ccc(C(=O)O)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O -US20070027173A1,2,O=C(Cl)N1CCCCC1.O=C1OC2(CCN(C(=O)c3c[nH]c4cc(Cl)ccc34)CC2)c2ccccc21>>O=C1OC2(CCN(C(=O)c3cn(C(=O)N4CCCCC4)c4cc(Cl)ccc34)CC2)c2ccccc21 -US20040102450A1,6,C#CCN1CCN(Cc2cc3cnccc3n2C(=O)OC(C)(C)C)C(=O)C1>>C#CCN1CCN(Cc2cc3cnccc3[nH]2)C(=O)C1 -US20080300280A1,2,CC(=O)OC(C)=O.CCNS(=O)(=O)c1cccc(C)c1C#N>>CCN(C(C)=O)S(=O)(=O)c1cccc(C)c1C#N -US20150284378A1,2,CC(C)(C)OC(=O)N1CCC(COc2sncc2N)CC1.O=C(O)c1ccc(F)c(-c2c(F)cccc2F)n1>>CC(C)(C)OC(=O)N1CCC(COc2sncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)CC1 -US20090221653A1,1,NC[C@H](O)c1ccc(O)c2[nH]c(=O)sc12.O=CCCSCCCOCCc1ccccc1>>O=c1[nH]c2c(O)ccc([C@@H](O)CNCCCSCCCOCCc3ccccc3)c2s1 -US08822500B2,7,Cc1ccc(F)cc1CC(C)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(C)C3=O>>Cc1ccc(F)cc1CC(C)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)CN(C)C3=O -US20150225399A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC)c1=O.NCCN1CCNC1=O>>CCn1c(=O)c(C(=O)NCCN2CCNC2=O)c(O)c2ncc(Cc3ccc(F)cc3)cc21 -US07585872B2,2,COC(=O)c1ccc(C(=O)O)cc1.COc1ccc(C2CC(OC(C)=O)CCC2N)cc1OC>>COC(=O)c1ccc(C(=O)NC2CCC(OC(C)=O)CC2c2ccc(OC)c(OC)c2)cc1 -US20100256124A1,3,C=CC[Sn](CCCC)(CCCC)CCCC.COc1ccc2ccc(=O)n(C)c2c1Br>>C=CCc1c(OC)ccc2ccc(=O)n(C)c12 -US20110065702A1,3,C=Cc1ccc(CN2CCOCC2)cc1.C[Si](C)(C)CCOCn1nc(I)c2ccc(C=O)cc21>>C[Si](C)(C)CCOCn1nc(/C=C/c2ccc(CN3CCOCC3)cc2)c2ccc(C=O)cc21 -US20040220191A1,2,CN(C)C1CCN(c2ccc(N)cc2)C1.O=C(O)c1ccc(-c2ccc(F)cc2F)cc1>>CN(C)C1CCN(c2ccc(NC(=O)c3ccc(-c4ccc(F)cc4F)cc3)cc2)C1 -US04535183,7,CC(=O)Oc1cccc(OCc2ccccc2C(=O)O)c1C=O>>O=Cc1c(O)cccc1OCc1ccccc1C(=O)O -US20040132769A1,3,Cc1c(Br)cc(Cl)c(N)c1F.OB(O)C1CC1>>Cc1c(C2CC2)cc(Cl)c(N)c1F -US06861418B2,3,CCN(CC)CCNC(=O)c1cc(C)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2cccc(Br)c2)N1>>CCN(CC)CCNC(=O)c1cc(C)c(C=C2C(=O)Nc3cccc(-c4cccc(Br)c4)c32)[nH]1 -US05130119,6,CC(=O)OCC(=O)Nc1cc(F)cc(C(=O)NCC(F)(F)F)c1O>>O=C(CO)Nc1cc(F)cc(C(=O)NCC(F)(F)F)c1O -US05736540,2,O=C(Cl)c1ccc([N+](=O)[O-])cc1Cl.c1ccc2c(c1)NCCc1cccn1-2>>O=C(c1ccc([N+](=O)[O-])cc1Cl)N1CCc2cccn2-c2ccccc21 -US20150191474A1,3,CCSc1ccccc1B1OC(C)(C)C(C)(C)O1.FC(F)(F)c1ccc2nc(Cl)cnc2c1>>CCSc1ccccc1-c1cnc2cc(C(F)(F)F)ccc2n1 -US20150284386A1,2,CN1C(=O)C(C)(C)c2cc(F)c(N)cc21.O=C(O)c1ccncc1>>CN1C(=O)C(C)(C)c2cc(F)c(NC(=O)c3ccncc3)cc21 -US07582626B2,1,CC(C)CC=O.COC(=O)[C@@H]1CCCCC[C@@H]1N>>COC(=O)[C@@H]1CCCCC[C@@H]1NCCC(C)C -US20150166512A1,2,CCc1ccc(Cl)cc1-c1[nH]ccc1C#N.O=S(=O)(Cl)c1ccccc1>>CCc1ccc(Cl)cc1-c1c(C#N)ccn1S(=O)(=O)c1ccccc1 -US20120316161A1,3,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.Cn1ccc2ccc(B3OC(C)(C)C(C)(C)O3)cc21>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2ccn(C)c2c1 -US20100029598A1,2,COc1ccc(C(=O)Cl)cc1OC.Cc1[nH]c2c(Cl)ccc(Cl)c2c1CCN>>COc1ccc(C(=O)NCCc2c(C)[nH]c3c(Cl)ccc(Cl)c23)cc1OC -US20100016337A1,2,Nc1nccs1.O=C(O)COc1nc(-c2ccc(F)cc2)cs1>>O=C(COc1nc(-c2ccc(F)cc2)cs1)Nc1nccs1 -US20120083482A1,2,CN(C(=O)CC(=O)O)c1ccccc1.Cn1ccnc1-c1cc2nccc(Oc3ccc(N)cc3F)c2s1>>CN(C(=O)CC(=O)Nc1ccc(Oc2ccnc3cc(-c4nccn4C)sc23)c(F)c1)c1ccccc1 -US20100240638A1,9,CC(C)(C)OC(=O)N1Cc2ccc(Br)cc2C1.[C-]#N>>CC(C)(C)OC(=O)N1Cc2ccc(C#N)cc2C1 -US04006145,7,O=C(O)c1cc(F)ccc1Sc1ccccc1>>OCc1cc(F)ccc1Sc1ccccc1 -US05948911,1,COC(=O)c1ccc(-c2nc(Cl)c3c(C)c(C)sc3n2)cc1.NCc1ccc2c(c1)OCO2>>COC(=O)c1ccc(-c2nc(NCc3ccc4c(c3)OCO4)c3c(C)c(C)sc3n2)cc1 -US20140134133A1,3,C#CC(C)O.COc1ncc(-c2ccc3nnc(Br)n3c2)cc1NS(=O)(=O)c1ccc(F)cc1F>>COc1ncc(-c2ccc3nnc(C#CC(C)O)n3c2)cc1NS(=O)(=O)c1ccc(F)cc1F -US20120302541A1,6,COC(=O)c1ccc(Oc2cc(-c3ccccc3)ccc2NC[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1CNc1ccc(-c2ccccc2)cc1Oc1ccc(C(=O)O)cc1 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)c1cc2ccccc2o1>>CC(C)C[C@H]1CN(C(=O)c2cc3ccccc3o2)[C@@H](CC(C)C)C(=O)N1 -US05814646,1,COc1ccc2nc(Cl)ccc2c1.Nc1ccc(S)cc1>>COc1ccc2nc(Sc3ccc(N)cc3)ccc2c1 -US06147087,3,COC(=O)CC(C)=O.O=Cc1cccc(Cl)c1Cl>>COC(=O)C(=Cc1cccc(Cl)c1Cl)C(C)=O -US07935712B2,9,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1cc(Br)ccc1O2.[C-]#N>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1cc(C#N)ccc1O2 -US20140364432A1,1,Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CN)c(-c2ccc(F)cc2)s1.Clc1ncc(Br)cn1>>Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncc(Br)cn2)c(-c2ccc(F)cc2)s1 -US06136831,4,CS(=O)(=O)c1ccc(NN)cc1.O=C(CC(=O)C(F)F)c1nc2cccc(F)c2s1>>CS(=O)(=O)c1ccc(-n2nc(C(F)F)cc2-c2nc3cccc(F)c3s2)cc1 -US06867224B2,9,COC(=O)CC1Cc2ccc(S(=O)(=O)Cl)cc2C1>>COC(=O)CC1Cc2ccc(S)cc2C1 -US04413010,2,CCCCNCCO.CCOC(=O)Cl>>CCCCN(CCO)C(=O)OCC -US04497817,6,COC(=O)c1ccc(-c2cn3c(n2)sc2ccccc23)cc1>>O=C(O)c1ccc(-c2cn3c(n2)sc2ccccc23)cc1 -US20020156081A1,2,COc1cc(Br)ccc1C(=O)Cl.NCc1ccccc1>>COc1cc(Br)ccc1C(=O)NCc1ccccc1 -US20150141406A1,2,CN.COc1nccc2c1c(-c1csc(C(=O)O)c1)nn2C1CCCC1>>CNC(=O)c1cc(-c2nn(C3CCCC3)c3ccnc(OC)c23)cs1 -US08314103B2,2,Cc1nc(-c2ccc(N)cn2)nc(O)c1Cl.O=C(Cl)C(Cl)c1ccccc1>>Cc1nc(-c2ccc(NC(=O)C(Cl)c3ccccc3)cn2)nc(O)c1Cl -US08901136B2,2,NS(=O)(=O)Cl.O=C(N[C@@H]1C[C@H](CO)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1)c1ccncc1>>NS(=O)(=O)OC[C@H]1C[C@@H](NC(=O)c2ccncc2)[C@H](OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1 -US04822528,1,C=C1C[C@H]2[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C(O)=C12.CI>>C=C1C[C@H]2[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C(OC)=C12 -US20090048269A1,1,COc1cc(N)cc(OC)c1OC.Cc1cccc(-c2nc(C)c(C)cc2Oc2ccnc(Cl)c2)n1>>COc1cc(Nc2cc(Oc3cc(C)c(C)nc3-c3cccc(C)n3)ccn2)cc(OC)c1OC -US20030149060A1,1,CCn1cnc2c(N)nc(Cl)nc21.NCc1ccccc1>>CCn1cnc2c(N)nc(NCc3ccccc3)nc21 -US20100216798A1,3,CN(C)c1ccc(B(O)O)cn1.O[C@@H]1CC[C@@H](Nc2ccc3ncc(I)n3n2)CC1>>CN(C)c1ccc(-c2cnc3ccc(N[C@@H]4CC[C@@H](O)CC4)nn23)cn1 -US06025350,6,COC1CN(C(=O)CNC(=O)OC(C)(C)C)Cc2ccccc21>>COC1CN(C(=O)CN)Cc2ccccc21 -US08912329B2,2,CC(C)CC(=O)Cl.c1ccc(C2CNCCO2)cc1>>CC(C)CC(=O)N1CCOC(c2ccccc2)C1 -US04224438,2,CCCCCCO.Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(O)C(=O)O)[C@@H](O)[C@H]1O>>CCCCCCOC(=O)C(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O -US20140194628A1,3,CCCCCC[Mg+].CCCc1nc2cnc3ccccc3c2n1CCCC(=O)N(C)OC>>CCCCCCC(=O)CCCn1c(CCC)nc2cnc3ccccc3c21 -US05219871,1,CNCCCC(C(N)=O)(c1ccccc1)c1ccccc1.Cc1ccc(CCBr)cc1>>Cc1ccc(CCN(C)CCCC(C(N)=O)(c2ccccc2)c2ccccc2)cc1 -US20120010186A1,1,CC(C)(C)OC(=O)N1CC2(CNC2)C1.Fc1ccc(Cl)c(I)c1>>CC(C)(C)OC(=O)N1CC2(C1)CN(c1cc(F)ccc1Cl)C2 -US20130281657A1,2,CC(C)(C)OC(=O)CN.O=C(N[C@@H](Cc1ccc(O)cc1)C(=O)O)OCC1c2ccccc2-c2ccccc21>>CC(C)(C)OC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21 -US07279497B2,7,COC(OC)[C@]1(C)Oc2ccc([N+](=O)[O-])cc2[C@H](N(Cc2ncc[nH]2)c2ccc(Cl)cc2)[C@H]1O>>COC(OC)[C@]1(C)Oc2ccc(N)cc2[C@H](N(Cc2ncc[nH]2)c2ccc(Cl)cc2)[C@H]1O -US20140303186A1,6,CCOC(=O)Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)nc2)c2ccccc12>>O=C(O)Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)nc2)c2ccccc12 -US20140371199A1,2,CN1CCN(C2CCNCC2)CC1.N#Cc1ccc(-c2cnn3ccc(-c4ccc(C(=O)O)cc4)nc23)cc1>>CN1CCN(C2CCN(C(=O)c3ccc(-c4ccn5ncc(-c6ccc(C#N)cc6)c5n4)cc3)CC2)CC1 -US08841289B2,2,CN.Cc1ccc(Br)cc1C(=O)O>>CNC(=O)c1cc(Br)ccc1C -US07049444B2,1,CCCC[Sn](Cl)(CCCC)CCCC.Ic1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CCCC[Sn](CCCC)(CCCC)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US08846910B2,3,CC1(C)O[C@@H]2O[C@H](/C=C/c3ccc(Br)cc3)[C@H](CCn3nnc4ccccc4c3=O)[C@@H]2O1.OB(O)c1cncnc1>>CC1(C)O[C@@H]2O[C@H](/C=C/c3ccc(-c4cncnc4)cc3)[C@H](CCn3nnc4ccccc4c3=O)[C@@H]2O1 -US07235548B2,3,COc1ccccc1B(O)O.O=S1(=O)NC(C2CCCCC2)=Nc2c(Cl)ccc(I)c21>>COc1ccccc1-c1ccc(Cl)c2c1S(=O)(=O)NC(C1CCCCC1)=N2 -US08178668B2,2,CNC.Nc1ncc(-c2cnn([C@@H]3CN[C@H](C(=O)O)C3)c2)cc1-c1cc2c(Cl)ccc(F)c2cn1>>CN(C)C(=O)[C@@H]1C[C@H](n2cc(-c3cnc(N)c(-c4cc5c(Cl)ccc(F)c5cn4)c3)cn2)CN1 -US06737435B1,1,CCOC(=O)c1cc2cc(OC(C)=O)ccc2[nH]1.Clc1ccc(CBr)cc1Cl>>CCOC(=O)c1cc2cc(OC(C)=O)ccc2n1Cc1ccc(Cl)c(Cl)c1 -US06414003B1,9,CC(c1c[nH]c2cc(F)ccc12)C1(C(=O)OCc2ccccc2)OC(N(C)C)=NC1=O>>CC(c1c[nH]c2cc(F)ccc12)C1OC(N(C)C)=NC1=O -US20150284713A1,6,CC(=O)SCCCCCC(=O)NCCCCCNC(=O)OC(C)(C)C>>CC(=O)SCCCCCC(=O)NCCCCCN -US20120329830A1,2,FC1CCNCC1.Nc1ccc2cc(-c3ccccc3C(=O)O)ccc2n1>>Nc1ccc2cc(-c3ccccc3C(=O)N3CCC(F)CC3)ccc2n1 -US06602877B1,2,CC1(N)COC(c2nc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)OC1.CS(=O)(=O)Cl>>CC1(NS(C)(=O)=O)COC(c2nc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)OC1 -US05252572,2,Cc1cccc2ncc(C(=O)O)c(=O)n12.NC1CCCC1>>Cc1cccc2ncc(C(=O)NC3CCCC3)c(=O)n12 -US07851473B2,1,N#C[S-].O=C(CBr)c1cccc(Cl)c1>>N#CSCC(=O)c1cccc(Cl)c1 -US08138206B2,1,CC(C)N1CC2(CCN(c3ccc(O)cc3)CC2)OCC1=O.C[C@@H]1CCCN1CCCBr>>CC(C)N1CC2(CCN(c3ccc(OCCCN4CCC[C@H]4C)cc3)CC2)OCC1=O -US20100069367A1,3,CC(=O)Nc1ccc(B(O)O)cc1.O=C(Nc1ccc(Br)cc1)c1cc(C(F)(F)F)nn1-c1ccccc1Cl>>CC(=O)Nc1ccc(-c2ccc(NC(=O)c3cc(C(F)(F)F)nn3-c3ccccc3Cl)cc2)cc1 -US07265147B2,2,COc1ccc(C(O)(C(=O)O)C2CCCC2)cc1.OCC#CCN1CC2CC2C1>>COc1ccc(C(O)(C(=O)OCC#CCN2C[C@@H]3C[C@@H]3C2)C2CCCC2)cc1 -US20140212486A1,2,CC(C)=CCC[C@@H](C)O.CS(=O)(=O)Cl>>CC(C)=CCC[C@@H](C)OS(C)(=O)=O -US08324396B2,7,N#CC=C1c2ccccc2-c2ccccc21>>N#CCC1c2ccccc2-c2ccccc21 -US20100227870A1,6,CC(C)(C)OC(=O)N1CCN(c2cccc(C(F)(F)F)c2Cl)CC1>>FC(F)(F)c1cccc(N2CCNCC2)c1Cl -US07632840B2,1,COCCN.COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1C=O>>COCCNCc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC -US07429609B2,2,CCO.O=C(O)c1n[nH]c2ccc(Br)cc12>>CCOC(=O)c1n[nH]c2ccc(Br)cc12 -US20140057895A1,2,CNOC.O=C(O)c1n[nH]c2c(F)cccc12>>CON(C)C(=O)c1n[nH]c2c(F)cccc12 -US07893099B2,1,CO[C@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2Cl)C[C@@H]1C(=O)NC1(C#N)CC1.Oc1ccc(F)cc1>>CO[C@H]1C[C@@H](S(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2Cl)C[C@@H]1C(=O)NC1(C#N)CC1 -US20130102576A1,1,COC(=O)CBr.COc1cc2c(cc1OC)CNCC2>>COC(=O)CN1CCc2cc(OC)c(OC)cc2C1 -US05420298,9,COC1(c2cc(F)cc(Sc3ccc(C(C)=O)cc3)c2)CCN(CC(F)(F)F)C1.NO>>COC1(c2cc(F)cc(Sc3ccc(C(C)=NO)cc3)c2)CCN(CC(F)(F)F)C1 -US20110237791A1,1,COc1nc(/C(=C/CO)c2ccc(C(C)(C)C)cc2)ccc1Cl.Oc1ccccc1>>COc1nc(/C(=C/COc2ccccc2)c2ccc(C(C)(C)C)cc2)ccc1Cl -US20150191483A1,6,O=S(=O)(c1cccc(Br)c1)C1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCN(Cc2ccccc2)C1>>O=S(=O)(c1cccc(Br)c1)C1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCNC1 -US04918092,6,CCCc1c(OCC2(O)COc3ccc(CC(=O)OC)cc3OC2)ccc(C(C)=O)c1O>>CCCc1c(OCC2(O)COc3ccc(CC(=O)O)cc3OC2)ccc(C(C)=O)c1O -US20150053900A1,1,N#Cc1c(Cl)c(Cl)c(Cl)c(Cl)c1C#N.Oc1ccccc1-c1ccccc1>>N#Cc1c(Cl)c(Cl)c(Oc2ccccc2-c2ccccc2)c(Cl)c1C#N -US07291744B2,7,CC(=O)NCCCc1ccc(F)cc1>>CCNCCCc1ccc(F)cc1 -US20050277676A1,4,NC(=S)c1ccccc1N.O=C(CBr)C1CCCC1>>Nc1ccccc1-c1nc(C2CCCC2)cs1 -US05811439,1,CC(Br)c1ccccc1.O=Cc1c[nH]c2ccccc12>>CC(c1ccccc1)n1cc(C=O)c2ccccc21 -US20090318690A1,2,C#CC1(CO)CC1.CS(=O)(=O)Cl>>C#CC1(COS(C)(=O)=O)CC1 -US20110059019A1,2,NCCCCO.O=C(O)c1ccc2ncccc2c1>>O=C(NCCCCO)c1ccc2ncccc2c1 -US20100137313A1,6,CCOC(=O)/C=C/c1cccc(-c2cnc(Nc3cccc(S(C)(=O)=O)c3)nc2-n2nc(C(F)(F)F)cc2C)c1>>Cc1cc(C(F)(F)F)nn1-c1nc(Nc2cccc(S(C)(=O)=O)c2)ncc1-c1cccc(/C=C/C(=O)O)c1 -US07229987B2,4,O=C(CSCCOc1ccccc1)NNC(=O)c1ccc(O)cc1>>Oc1ccc(-c2nnc(CSCCOc3ccccc3)o2)cc1 -US08134007B2,3,COc1ccc(Cl)c(B(O)O)c1.Nc1ccc(I)c(N)n1>>COc1ccc(Cl)c(-c2ccc(N)nc2N)c1 -US20060111353A1,1,BrCc1cccnc1.Sc1ccc(Br)cc1>>Brc1ccc(SCc2cccnc2)cc1 -US07429609B2,2,CC(C)(C)OC(=O)NN.COc1c(C(=O)O)ccc2c1c(/C=C/c1cccc(F)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1c(C(=O)NNC(=O)OC(C)(C)C)ccc2c1c(/C=C/c1cccc(F)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1 -US20090247567A1,2,CC(=O)NCCN.CN(C(=O)c1cc2c(s1)-c1ccccc1OCC2)c1ccc(C(=O)O)cc1Cl>>CC(=O)NCCNC(=O)c1ccc(N(C)C(=O)c2cc3c(s2)-c2ccccc2OCC3)c(Cl)c1 -US20100160308A1,1,C1CCNC1.NC(=O)c1sc(-n2cnc3ccc(OCCCCl)cc32)nc1-c1cccc(Cl)c1>>NC(=O)c1sc(-n2cnc3ccc(OCCCN4CCCC4)cc32)nc1-c1cccc(Cl)c1 -US08309059B2,7,O=NN1CCCc2ccccc21>>NN1CCCc2ccccc21 -US20090111794A1,6,CC(C)(C)OC(=O)NCC(=O)N1C[C@H]2C[C@@H]1CN2Cc1ccc(Oc2nc3ccccc3s2)cc1>>NCC(=O)N1C[C@H]2C[C@@H]1CN2Cc1ccc(Oc2nc3ccccc3s2)cc1 -US07094798B1,1,C=CCCBr.COc1ccc(CN2C(=O)c3c(-c4ccccc4Cl)cc4[nH]c5ccc(OC)cc5c4c3C2=O)c(OC)c1>>C=CCCn1c2ccc(OC)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)N(Cc1ccc(OC)cc1OC)C3=O -US20130303508A1,6,CC(C)(C)OC(=O)N1CC=C(c2ccc(NC(=O)Nc3ccc4nccn4c3)cc2)CC1>>O=C(Nc1ccc(C2=CCNCC2)cc1)Nc1ccc2nccn2c1 -US07348348B2,3,Clc1ccccc1I.O=Cc1ccc(B(O)O)s1>>O=Cc1ccc(-c2ccccc2Cl)s1 -US07012085B2,1,BrCC1CCC2(CC1)OCCO2.COc1ccccc1C1CCNC1>>COc1ccccc1C1CCN(CC2CCC3(CC2)OCCO3)C1 -US20120157434A1,9,CC(=O)NC[C@@H]1OC(=O)N2c3ccc(Br)cc3C[C@@H]12.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(=O)NC[C@@H]1OC(=O)N2c3ccc(B4OC(C)(C)C(C)(C)O4)cc3C[C@@H]12 -US20140249126A1,1,CCI.COc1ccc2[nH]c(=O)oc(=O)c2c1OC>>CCn1c(=O)oc(=O)c2c(OC)c(OC)ccc21 -US07179912B2,1,CC(=O)c1ccc(O)cc1O.OC1CCOCC1>>CC(=O)c1ccc(OC2CCOCC2)cc1O -US20050009843A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](OC(N)=O)C1>>NC(=O)O[C@@H]1CCCNC1 -US06262059B1,9,Clc1ccc2nc(Cl)nc(NCc3ccc4c(c3)OCO4)c2c1.N>>Nc1nc(NCc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1 -US09000025B2,1,CCn1cc(Br)cn1.COC(=O)c1cccc(Sc2c(C)[nH]c3cc(C#N)ccc23)c1>>CCn1cc(-n2c(C)c(Sc3cccc(C(=O)OC)c3)c3ccc(C#N)cc32)cn1 -US20120028919A1,3,Brc1ccc2cnc(Nc3ccc(N4CCOCC4)cc3)nn12.O=S1(=O)CCN(Cc2ccc(B(O)O)cc2)CC1>>O=S1(=O)CCN(Cc2ccc(-c3ccc4cnc(Nc5ccc(N6CCOCC6)cc5)nn34)cc2)CC1 -US20070167449A1,6,COc1ccc(Nc2ncc(-c3ccsc3)s2)c(C(F)(F)F)c1>>Oc1ccc(Nc2ncc(-c3ccsc3)s2)c(C(F)(F)F)c1 -US20060276515A1,2,NCCC(c1ccc(F)cc1)c1ccc(F)cc1.O=C(O)c1cccnc1>>O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)c1cccnc1 -US20130296327A1,2,CN1CCN(c2cc(-c3ccc4c(c3)CNCC4)nc(N)n2)CC1.O=S(=O)(Cl)c1ccccc1>>CN1CCN(c2cc(-c3ccc4c(c3)CN(S(=O)(=O)c3ccccc3)CC4)nc(N)n2)CC1 -US20140005195A1,2,CS(=O)(=O)c1cc(CN)nc(-c2ccccn2)c1.O=S(=O)(Cl)c1ccc(Cl)s1>>CS(=O)(=O)c1cc(CNS(=O)(=O)c2ccc(Cl)s2)nc(-c2ccccn2)c1 -US20110257208A1,1,O=CC1CCOCC1.c1ccc2ncc(Nc3ncnc4c3CNC4)cc2c1>>c1ccc2ncc(Nc3ncnc4c3CN(CC3CCOCC3)C4)cc2c1 -US20060019985A1,6,CC(C)(C)OC(=O)N1CCC(C(=O)N[C@H]2CCN(Cc3ccccc3)C2)CC1>>CC(C)(C)OC(=O)N1CCC(C(=O)N[C@H]2CCNC2)CC1 -US20080119653A1,9,Cc1c(C(=O)Cl)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1.NN>>Cc1c(C(=O)NN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 -US07560558B2,3,COc1cc2nccc(Oc3ccc(C)cc3Br)c2cc1OC.O=C(Cl)C1CCCC1>>COc1cc2nccc(Oc3ccc(C)cc3C(=O)C3CCCC3)c2cc1OC -US05877193,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1nc(-c2cccc(Br)c2)cs1>>Cc1ccc(S(=O)(=O)Nc2nc(-c3cccc(Br)c3)cs2)cc1 -US20120016122A1,1,Cc1cnc(Cl)nc1Cl.Nc1ccc2oc(=O)[nH]c2c1>>Cc1cnc(Cl)nc1Nc1ccc2oc(=O)[nH]c2c1 -US20070247585A1,10,CCOc1ccc(C2=CCC(C3CCC4(CC3)OCCO4)CC2)c(F)c1F.O>>CCOc1ccc(C2CCC(C3CCC4(CC3)OCCO4)CC2O)c(F)c1F -US07122567B2,6,CC(C)(C)OC(=O)N[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1>>N[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1 -US07977354B2,6,COc1ccc2cc(C3=NC(C)(C)CO3)cnc2c1>>CC1(C)COC(c2cnc3cc(O)ccc3c2)=N1 -US20050197331A1,4,COc1ccccc1C(=O)O.Nc1ccc([N+](=O)[O-])cc1N>>COc1ccccc1-c1nc2ccc([N+](=O)[O-])cc2[nH]1 -US06518257B1,3,CC(C)C(O)(c1ccc(B(O)O)cc1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.CC(C)NC(=O)c1cccc(Br)n1>>CC(C)NC(=O)c1cccc(-c2ccc(C(O)(c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)C(C)C)cc2)n1 -US04059433,2,CC(C)C(=O)OC(=O)C(C)C.CC(C)Oc1nsc(N)c1C#N>>CC(C)Oc1nsc(NC(=O)C(C)C)c1C#N -US07179832B2,6,COC(=O)c1ccc(O)c2[nH]c(-c3ccc(F)c(Cl)c3)nc12>>O=C(O)c1ccc(O)c2[nH]c(-c3ccc(F)c(Cl)c3)nc12 -US05591735,7,C[C@]12C[C@H]3O[C@H]3C[C@@H]1CC[C@H]1[C@@H]3C[C@H](N4CCC(O)CC4)C(=O)[C@@]3(C)CC[C@@H]12>>C[C@]12C[C@H]3O[C@H]3C[C@@H]1CC[C@H]1[C@@H]3C[C@H](N4CCC(O)CC4)[C@H](O)[C@@]3(C)CC[C@@H]12 -US20080293949A1,6,CC(=O)Oc1ccc(C(=Cc2ccc(C)cc2)C(=O)O)cc1>>Cc1ccc(C=C(C(=O)O)c2ccc(O)cc2)cc1 -US04529438,7,CCOC(=O)C=C(OC)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1>>COC(=CCO)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1 -US20040122001A1,3,CCOC(=O)CP(=O)(OCC)OCC.N#Cc1ccc2c(c1)CCCC2=O>>CCOC(=O)C=C1CCCc2cc(C#N)ccc21 -US06951868B2,3,C=CCOc1c(C=C)cc(CO)nc1Cl>>OCc1cc2c(c(Cl)n1)OCC=C2 -US03947417,2,NCCO.O=C(O)c1nc(CCl)n(-c2ccc(Cl)cc2C(=O)c2ccccc2)n1>>O=C(NCCO)c1nc(CCl)n(-c2ccc(Cl)cc2C(=O)c2ccccc2)n1 -US05968478,7,O=C1Cc2cc([N+](=O)[O-])ccc2Sc2ccccc21>>Nc1ccc2c(c1)CC(=O)c1ccccc1S2 -US07378417B2,2,CS(=O)(=O)c1cccc(N)c1.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)c(Cl)c3)nc12>>CS(=O)(=O)c1cccc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)c(Cl)c4)nc23)c1 -US08729105B2,1,O=C(O)c1cnc(Cl)c(-c2ccc(Cl)cc2)c1.O[C@@H]1CCOC1>>O=C(O)c1cnc(O[C@@H]2CCOC2)c(-c2ccc(Cl)cc2)c1 -US06344462B1,2,CNC(=O)c1ccc(N)cc1.O=C(Cl)Oc1ccccc1>>CNC(=O)c1ccc(NC(=O)Oc2ccccc2)cc1 -US05182399,1,COc1ccc(CCBr)cc1.O=C(c1nc2ccccc2n1Cc1ccc(F)cc1)C1CCNCC1>>COc1ccc(CCN2CCC(C(=O)c3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1 -US07217723B2,9,CN(C[C@@H](O)c1ccc(F)cc1)S(=O)(=O)c1csc2c1CCCC2=O.NO>>CN(C[C@@H](O)c1ccc(F)cc1)S(=O)(=O)c1csc2c1CCC/C2=N/O -US05854234,9,Cc1cc(C(F)(F)F)cc(Cl)n1.[NH4+]>>Cc1cc(C(F)(F)F)cc(N)n1 -US20110294780A1,1,O=C1NC(=O)/C(=C/c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)S1.OC[C@H]1CN2CCOC[C@H]2CO1>>O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1C[C@H]1CN2CCOC[C@H]2CO1 -US08466154B2,3,CC(=O)c1cncc(Br)c1.OB(O)c1ccccc1>>CC(=O)c1cncc(-c2ccccc2)c1 -US04971993,6,O=C(OCc1ccccc1)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccccc1>>O=C(O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccccc1 -US20070270421A1,1,Nc1cc(Cl)ccn1.O=[N+]([O-])c1ccc(O)c(F)c1>>Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ccn1 -US20140378487A1,1,N#Cc1cncc(O)c1.O=Cc1ccc(F)cc1>>N#Cc1cncc(Oc2ccc(C=O)cc2)c1 -US20070142638A1,6,COC(=O)CCc1ccccc1NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NCc1ccc2ccccc2n1>>O=C(O)CCc1ccccc1NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NCc1ccc2ccccc2n1 -US08178699B2,6,COC(=O)c1sccc1NS(=O)(=O)c1ccc(N2CCCC2)c(C)c1>>Cc1cc(S(=O)(=O)Nc2ccsc2C(=O)O)ccc1N1CCCC1 -US20080249301A1,3,CC(Oc1cc(-n2cnc3cc(Br)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F.Cc1cc(B(O)O)ccn1>>Cc1cc(-c2ccc3c(c2)ncn3-c2cc(O[C@H](C)c3ccccc3C(F)(F)F)c(C(N)=O)s2)ccn1 -US20080194616A1,1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.CC(C)Nc1nc2ccccn2c(=O)c1-c1ccc(Cl)cc1>>CC(C)Nc1nc2ccccn2c(=O)c1-c1ccc(N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1 -US08927536B2,6,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(-c5ccn[nH]5)cc4)CC3)n2CCS1>>CC1(CO)Cc2nnc(C3(c4ccc(-c5ccn[nH]5)cc4)CC3)n2CCS1 -US20140142084A1,6,COc1cc(OC)c(F)c(COc2cnc(Nc3cc(CCOCc4ccccc4)n(C)n3)nc2)c1F>>COc1cc(OC)c(F)c(COc2cnc(Nc3cc(CCO)n(C)n3)nc2)c1F -US04190674,2,NC1CC1.O=C(Cl)/C=C/c1cccc(Br)c1>>O=C(/C=C/c1cccc(Br)c1)NC1CC1 -US20100137303A1,2,C=CCN=C=O.Nc1nc2cc(Br)cnc2s1>>C=CCNC(=O)Nc1nc2cc(Br)cnc2s1 -US04416890,2,NS(=O)(=O)c1nc2ccc(O)cc2s1.O=C(Cl)c1ccccc1>>NS(=O)(=O)c1nc2ccc(OC(=O)c3ccccc3)cc2s1 -US20100076014A1,2,Nc1nncs1.O=C(O)CC(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1>>O=C(CC(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1)Nc1nncs1 -US07435744B2,1,O=C(CCl)Nc1ccc2[nH]cnc2c1.c1ccc(CC2CCNCC2)cc1>>O=C(CN1CCC(Cc2ccccc2)CC1)Nc1ccc2[nH]cnc2c1 -US06403586B1,1,BrCCCc1ccccc1.CCOC(=O)Nc1cc(-c2ccc(OC)cc2)nn(CC=Cc2ccc(Cl)cc2)c1=O>>CCOC(=O)N(CCCc1ccccc1)c1cc(-c2ccc(OC)cc2)nn(CC=Cc2ccc(Cl)cc2)c1=O -US20040024047A1,8,OCCc1ccc(F)cc1>>O=CCc1ccc(F)cc1 -US08163793B2,4,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2Cl)CN1C(=O)CC(C)=O.NNC1CCC1>>COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2Cl)CN1c1cc(C)nn1C1CCC1 -US20120302607A1,3,CC(C)(C)[Si](C)(C)OC(CCCCCCc1ccccc1)c1nc(Br)co1.CCCC[Sn](CCCC)(CCCC)c1cccnc1>>CC(C)(C)[Si](C)(C)OC(CCCCCCc1ccccc1)c1nc(-c2cccnc2)co1 -US07410976B2,6,COC(=O)c1cc(OC)c2ccnc(C3CC3)c2c1>>COc1cc(C(=O)O)cc2c(C3CC3)nccc12 -US20140018577A1,2,COC[C@@H](NC(C)=O)C(=O)O.NCc1ccccc1>>COC[C@@H](NC(C)=O)C(=O)NCc1ccccc1 -US08883782B2,1,COc1ccc(O)c(F)c1F.O=C(O)c1cc(Br)ccc1Br>>COc1ccc(Oc2ccc(Br)cc2C(=O)O)c(F)c1F -US20090226398A1,3,CCCOc1ccc(B(O)O)cc1.O=[N+]([O-])c1cc(Cn2cc3nc(-c4cccc(F)c4F)nc-3cn2)ccc1Br>>CCCOc1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)cc2[N+](=O)[O-])cc1 -US20070270437A1,9,COC(=O)c1sc(-n2cnc3ccc(CSC)cc32)cc1O[C@H](C)c1ccccc1C(F)(F)F.N>>CSCc1ccc2ncn(-c3cc(O[C@H](C)c4ccccc4C(F)(F)F)c(C(N)=O)s3)c2c1 -US20150152113A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cccc(F)c1C1CCN(c2cn[nH]c(=O)c2Br)CC1>>COc1cccc(F)c1C1CCN(c2cnn(C(=O)OC(C)(C)C)c(=O)c2Br)CC1 -US04138588,7,CCCCC(C=O)CC>>CCCCC(CC)CO -US04447441,2,CN.COC(=O)CCSCc1csc(NC(N)=NCC(F)(F)F)n1>>CNC(=O)CCSCc1csc(NC(N)=NCC(F)(F)F)n1 -US08710049B2,6,O=C(Nc1ccccc1)N[C@@H]1CCCC[C@H]1NC1CCCN(Cc2ccccc2)C1>>O=C(Nc1ccccc1)N[C@@H]1CCCC[C@H]1NC1CCCNC1 -US20040133008A1,9,COC(=O)c1ccc(C(C)O)cc1N(C)C>>CCc1ccc(C(=O)OC)c(N(C)C)c1 -US04002746,7,CC[C@]12CCC3=C(CCc4cc(O)ccc43)C1=CC[C@@H]2O>>CC[C@]12CCC3=C(CCc4cc(O)ccc43)[C@@H]1CC[C@@H]2O -US20060148888A1,7,O=C(O)CC1CCOc2cc(S(=O)(=O)c3cccc(F)c3)ccc21>>O=S(=O)(c1cccc(F)c1)c1ccc2c(c1)OCCC2CCO -US20070208005A1,1,Brc1ccc(Cc2ccc3c(c2)CCN(C2CCC2)CC3)cn1.O=C1NCCO1>>O=C1OCCN1c1ccc(Cc2ccc3c(c2)CCN(C2CCC2)CC3)cn1 -US20080306124A1,3,O=C(O)c1ccc(Cl)c(C(F)(F)F)c1.OB(O)c1ccccc1>>O=C(O)c1ccc(-c2ccccc2)c(C(F)(F)F)c1 -US20020006868A1,1,OCCOCc1ccccc1.Oc1ccc(OCc2ccccc2)cc1>>c1ccc(COCCOc2ccc(OCc3ccccc3)cc2)cc1 -US20020058665A1,8,COC(=O)c1cccnc1-c1ccc(F)cc1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1ccc[n+]([O-])c1-c1ccc(F)cc1 -US20140081025A1,2,NCCc1cn[nH]c1.O=C(O)c1ccccc1-n1nccn1>>O=C(NCCc1cn[nH]c1)c1ccccc1-n1nccn1 -US04772600,6,CCOC(=O)Cn1c(-c2ccccn2)nc2cccnc21>>O=C(O)Cn1c(-c2ccccn2)nc2cccnc21 -US20080181866A1,2,COc1ccc([C@@H]2NC(C(=O)O)CS2)cc1.O=C(Cl)OCc1ccccc1>>COc1ccc([C@H]2SCC(C(=O)O)N2C(=O)OCc2ccccc2)cc1 -US20140343053A1,3,CCCC[Sn](CCCC)(CCCC)c1ncco1.O=c1n(CCc2ccc3ccccc3n2)nc2c(Br)cccn12>>O=c1n(CCc2ccc3ccccc3n2)nc2c(-c3ncco3)cccn12 -US04910327,2,O=C(O)c1cc2ccccc2nc1C(=O)O>>O=C1OC(=O)c2nc3ccccc3cc21 -US08242145B2,1,COC(=O)Cc1cccc(Oc2ccc(Br)cc2CBr)c1.C[C@H]1NC(=O)O[C@@H]1Oc1ccc(Cl)cc1>>COC(=O)Cc1cccc(Oc2ccc(Br)cc2CN2C(=O)O[C@H](Oc3ccc(Cl)cc3)[C@H]2C)c1 -US09150568B2,9,NO.O=CC1CCC2CC2C1>>ON=CC1CCC2CC2C1 -US20090221555A1,1,CCN1CCc2ccc(N)cc2CC1.NC(=O)[C@@H]1CCC[C@@H]1Nc1nc(Cl)ncc1Cl>>CCN1CCc2ccc(Nc3ncc(Cl)c(N[C@H]4CCC[C@H]4C(N)=O)n3)cc2CC1 -US20040132801A1,1,CC(C)(C)OC(=O)C1CC(CO)CN1C(=O)OC(C)(C)C.Oc1cccc(Cl)c1>>CC(C)(C)OC(=O)[C@@H]1C[C@H](COc2cccc(Cl)c2)CN1C(=O)OC(C)(C)C -US20130303533A1,1,CCn1ncc2c(Cl)nc(S(=O)(=O)c3ccc(F)cc3)nc21.Cc1cc(N)n[nH]1>>CCn1ncc2c(Nc3cc(C)[nH]n3)nc(S(=O)(=O)c3ccc(F)cc3)nc21 -US08173650B2,6,O=C(OCc1ccccc1)N1CCN(C2COC2)CC12CC2>>C1CN(C2COC2)CC2(CC2)N1 -US20150158879A1,6,CC1(O)CCC2(CC1)OCCO2>>CC1(O)CCC(=O)CC1 -US20120196845A1,1,CC=O.Nc1ccccc1-n1nc2c3ccccc3n(Cc3ccc(-n4cccn4)cc3)cc-2c1=O>>CCNc1ccccc1-n1nc2c3ccccc3n(Cc3ccc(-n4cccn4)cc3)cc-2c1=O -US20030232833A1,9,CCc1c(C2(O)CCNCC2)sc2ccccc12>>CCc1c(C2CCNCC2)sc2ccccc12 -US09073864B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)c1ccc(NC(CCC(F)(F)F)c2ccc(Br)cc2C)cc1>>COC(=O)c1ccc(NC(CCC(F)(F)F)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2C)cc1 -US04282246,1,Cc1ccc(S)cc1.O=C(O)c1coc(Br)c1>>Cc1ccc(Sc2cc(C(=O)O)co2)cc1 -US05206364,7,CC(=O)OC[C@@](O)(c1ccc(F)cc1F)[C@H](C)c1ccncn1>>C[C@H](c1ccncn1)[C@@](O)(CO)c1ccc(F)cc1F -US20100317657A1,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(-c4ccc(N)nc4)cc3c21 -US07915267B2,2,CCOC(=O)c1nc2ccccc2c(=O)[nH]1.NCc1cccc(OCCCOc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)c1>>O=C(NCc1cccc(OCCCOc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)c1)c1nc2ccccc2c(=O)[nH]1 -US07812022B2,7,Nc1cccc(CCC(=O)N2CCOCC2)c1>>Nc1cccc(CCCN2CCOCC2)c1 -US06384051B1,2,C=CC(=O)Cl.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(Br)cc1>>C=CC(=O)Nc1ccc2ncc(C#N)c(Nc3ccc(Br)cc3)c2c1 -US20120022056A1,6,Cc1nnc(-c2cc3c(N4CCN(C(=O)OC(C)(C)C)CC4)cccc3o2)o1>>Cc1nnc(-c2cc3c(N4CCNCC4)cccc3o2)o1 -US05175281,7,O=[N+]([O-])c1ccc(N2CCCC2)cc1N1CCNCC1>>Nc1ccc(N2CCCC2)cc1N1CCNCC1 -US20070161574A1,6,CCC[C@H](NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1>>CCC[C@H](NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1)C(=O)NS(=O)(=O)c1ccccc1 -US04788204,2,CCO.O=C(O)CCc1cc2ccccc2c(-c2ccccc2)n1>>CCOC(=O)CCc1cc2ccccc2c(-c2ccccc2)n1 -US08314100B2,1,C[O-].Cc1cc2nc(N)c(Cl)nc2cc1C>>COc1nc2cc(C)c(C)cc2nc1N -US20040029814A1,1,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O.COC(=O)c1cccc(CBr)c1>>COC(=O)c1cccc(COC[C@H](NC(=O)OC(C)(C)C)C(=O)O)c1 -US05373008,1,CNC(=O)C(C)(C)C.Nc1ccccc1N1CCCCC1>>CNC(=Nc1ccccc1N1CCCCC1)C(C)(C)C -US04073917,1,CC(C)COc1ccccc1O.CCN(CC)CCCl>>CCN(CC)CCOc1ccccc1OCC(C)C -US20040102636A1,1,Cc1cncc(O)c1.O=[N+]([O-])c1cccc(Br)c1>>Cc1cncc(Oc2cccc([N+](=O)[O-])c2)c1 -US20060052600A1,3,CN(C)C=O.CN(C)Cc1ccc(-c2ccccc2)cc1>>CN(C)Cc1ccc(-c2ccccc2)cc1C=O -US05478843,1,CN1C(=O)CCc2cc(S)ccc21.CO[C@]1(c2cnc(Cl)s2)CCO[C@@H](C)C1>>CO[C@]1(c2cnc(Sc3ccc4c(c3)CCC(=O)N4C)s2)CCO[C@@H](C)C1 -US06166050,6,COC(=O)[C@H](Cc1ccccc1)Nc1c(NCc2ccccc2)c(=O)c1=O>>O=C(O)[C@H](Cc1ccccc1)Nc1c(NCc2ccccc2)c(=O)c1=O -US06245761B1,1,CN.Fc1ccc(Br)cc1COCC#CCBr>>CNCC#CCOCc1cc(Br)ccc1F -US20070254866A1,1,NCCNc1ccccn1.Nc1c(F)c(F)cc2c1c(=O)c(C(=O)O)cn2CCc1ccccc1>>Nc1c(F)c(NCCNc2ccccn2)cc2c1c(=O)c(C(=O)O)cn2CCc1ccccc1 -US20150225422A1,2,Nc1cncc(Br)c1.O=C(Cl)c1ccccc1>>O=C(Nc1cncc(Br)c1)c1ccccc1 -US20140155381A1,2,Cc1ccc(C(N)COC(C)C)c(C)c1.Cc1noc(C)c1C(O)c1cc2cc(CC(=O)O)ccc2o1>>Cc1ccc(C(COC(C)C)NC(=O)Cc2ccc3oc(C(O)c4c(C)noc4C)cc3c2)c(C)c1 -US04024273,3,CCN(CC)CCCOc1ccc(C(=O)Cl)cc1.c1ccc(-c2cc3ccccc3s2)cc1>>CCN(CC)CCCOc1ccc(C(=O)c2c(-c3ccccc3)sc3ccccc23)cc1 -US20090018166A1,2,CN(c1ccccc1)S(N)(=O)=O.N#Cc1cc(C(=O)C2CC2)c(CN2CCCCC2=O)nc1N1CCC(C(=O)O)CC1>>CN(c1ccccc1)S(=O)(=O)NC(=O)C1CCN(c2nc(CN3CCCCC3=O)c(C(=O)C3CC3)cc2C#N)CC1 -US20080139565A1,1,COC(=O)c1ccccc1NC(=O)N1CCNCC1.Clc1cnc2ccccc2n1>>COC(=O)c1ccccc1NC(=O)N1CCN(c2cnc3ccccc3n2)CC1 -US20150203447A1,2,CCCCCCN=C=O.COC(=O)C(C)c1ccc(-c2cccc(O)c2)c(F)c1>>CCCCCCNC(=O)Oc1cccc(-c2ccc(C(C)C(=O)OC)cc2F)c1 -US20150274705A1,1,Cc1c2ccc(N)cc2nn1C.Cc1cnc(Cl)nc1NC1CC2CN(C(=O)OC(C)(C)C)CC2C1>>Cc1cnc(Nc2ccc3c(C)n(C)nc3c2)nc1NC1CC2CN(C(=O)OC(C)(C)C)CC2C1 -US20100093757A1,6,COC[C@H](O[Si](C)(C)C(C)(C)C)C(=O)Nc1nc(C)ns1>>COC[C@H](O)C(=O)Nc1nc(C)ns1 -US20040063754A1,6,CCOC(=O)c1cn([C@@H]2C[C@@H]2F)c2c(C)c(F)cc(N)c2c1=O>>Cc1c(F)cc(N)c2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12 -US20100168156A1,6,COCOc1c(OC)cccc1SC(=S)N(C)C>>COc1cccc(SC(=S)N(C)C)c1O -US08912204B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(CNc2ccc(C=O)c(F)n2)cc1>>COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc(C=O)c(F)n2)cc1 -US20060142362A1,2,CCOC(=O)Cn1ccc(N)n1.O=C(O)c1ccc(Cl)s1>>CCOC(=O)Cn1ccc(NC(=O)c2ccc(Cl)s2)n1 -US20140163035A1,9,COC(=O)Cc1cccc(C(N)=O)c1Cl>>COC(=O)Cc1cccc(C#N)c1Cl -US20040242656A1,1,CC(C)(C)OC(=O)N1CCC(O)CC1.Fc1ccncc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccncc2)CC1 -US20080051405A1,1,CN1CCC(CO)C1.N#Cc1cccc(F)c1>>CN1CCC(COc2cccc(C#N)c2)C1 -US08022057B2,6,CCOC(=O)c1c(Cl)c(C)c(=O)n2c1CCC2>>Cc1c(Cl)c(C(=O)O)c2n(c1=O)CCC2 -US20130310379A1,2,CC1(C)CC(N)CC(C)(C)N1.Cc1cccc(OCc2ccc(C(=O)O)cc2)c1>>Cc1cccc(OCc2ccc(C(=O)NC3CC(C)(C)NC(C)(C)C3)cc2)c1 -US20080085905A1,2,COC(=O)[C@@H](N)CC(C)C.O=C(O)c1cnc(N2CCC(F)(F)CC2)c(OCC2CCCC2)n1>>COC(=O)[C@H](CC(C)C)NC(=O)c1cnc(N2CCC(F)(F)CC2)c(OCC2CCCC2)n1 -US04851526,1,CCNCC.CS(=O)(=O)OCC1CC1C#N>>CCN(CC)CC1CC1C#N -US20100099713A1,2,CC(=O)OC(C)=O.Cc1ncccc1Oc1cc(Nc2nc(C3CCNCC3)cs2)ncc1Sc1ccnc2ccsc12>>CC(=O)N1CCC(c2csc(Nc3cc(Oc4cccnc4C)c(Sc4ccnc5ccsc45)cn3)n2)CC1 -US05489686,1,CCOC(=O)C1Cc2c(ccc(OC)c2O)CN1C(=O)C(c1ccccc1)c1ccccc1.COC(=O)c1ccc(CBr)cc1>>CCOC(=O)C1Cc2c(ccc(OC)c2OCc2ccc(C(=O)OC)cc2)CN1C(=O)C(c1ccccc1)c1ccccc1 -US20140031345A1,7,O=Cc1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)c1>>OCc1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)c1 -US05567719,1,Cc1nc(-c2cc(C)c(O)c(C)c2)no1.Cc1nsc(CCCO)n1>>Cc1nsc(CCCOc2c(C)cc(-c3noc(C)n3)cc2C)n1 -US20130178443A1,1,CC(C)(C)N.Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3ccc(F)cc3C=O)ccc2n1>>CC(C)(C)NCc1cc(F)ccc1-c1ccc2nc(N)nc(C(=O)N3Cc4ccccc4C3)c2c1 -US20090036492A1,1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1ccc(C=O)c2ccccc12>>COc1cc(O)c2c(c1C(=O)NCc1ccc(C)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C -US08129385B2,6,CC(C)CN1CC2CCCC2N2C(=O)c3c(OCc4ccccc4)c(=O)c(C(=O)NCc4ccc(F)cc4F)cn3CC12>>CC(C)CN1CC2CCCC2N2C(=O)c3c(O)c(=O)c(C(=O)NCc4ccc(F)cc4F)cn3CC12 -US05627200,1,COC(CBr)OC.Cc1c(C(=O)O)oc2ccc(O)cc12>>COC(COc1ccc2oc(C(=O)O)c(C)c2c1)OC -US06066739,2,COC(=O)c1cc(C)c(C(O)c2cc(-n3ccnc3)ccc2C)c(C)c1.Cc1ccc(S(=O)(=O)N[C@@H](C)C(=O)Cl)cc1>>COC(=O)c1cc(C)c(C(OC(=O)[C@H](C)NS(=O)(=O)c2ccc(C)cc2)c2cc(-n3ccnc3)ccc2C)c(C)c1 -US20120101100A1,2,CC(=O)NN.Nc1ncc(Br)cc1C(=O)O>>CC(=O)NNC(=O)c1cc(Br)cnc1N -US04673746,8,COc1ccc(C(O)c2ccccn2)c(Cl)c1Cl>>COc1ccc(C(=O)c2ccccn2)c(Cl)c1Cl -US20090197875A1,2,COc1cc(N)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1.CS(=O)(=O)Cl>>COc1cc(NS(C)(=O)=O)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1 -US05292962,1,O[C@@H](CCCl)c1ccccc1.Oc1cccc2ccccc12>>O[C@@H](CCOc1cccc2ccccc12)c1ccccc1 -US08481542B2,3,CCOC(=O)c1cnc(N2CCN(c3nnc(Cl)c(C)c3C)C[C@H]2C)nc1C(F)(F)F.Fc1ccc(C[Zn+])c(F)c1>>CCOC(=O)c1cnc(N2CCN(c3nnc(Cc4ccc(F)cc4F)c(C)c3C)C[C@H]2C)nc1C(F)(F)F -US20090131431A1,2,CCn1ncc2c(NC3CCOCC3)c(CN)c(C)nc21.O=C(O)c1ccc(C(F)(F)F)nc1>>CCn1ncc2c(NC3CCOCC3)c(CNC(=O)c3ccc(C(F)(F)F)nc3)c(C)nc21 -US20130158009A1,1,N#Cc1ccc(F)c(F)c1.N[C@H]1CCN(C2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)C1=O>>N#Cc1ccc(N[C@H]2CCN(C3CCN(c4ncc(C(F)(F)F)cc4Cl)CC3)C2=O)c(F)c1 -US05780631,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)NCC1CN(C(c2ccccc2)c2ccccc2)C1 -US07368471B2,6,CCOC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3ccc(F)c(Cl)c3)cc12>>O=C(O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3ccc(F)c(Cl)c3)cc12 -US20050119231A1,7,O=C(OC1C(F)CC2CN(C(=O)OCc3ccccc3)CC21)c1ccccc1>>O=C(OCc1ccccc1)N1CC2CC(F)C(O)C2C1 -US20100062958A1,7,CCCCCCCCCCCCCC(C)=O>>CCCCCCCCCCCCCC(C)O -US08497281B2,2,Cc1cc(C(=O)O)ccc1O.c1ccc2c(c1)C[C@@H]1NCCC[C@H]21>>Cc1cc(C(=O)N2CCC[C@@H]3c4ccccc4C[C@@H]32)ccc1O -US20060025421A1,1,CN1CCNCC1.O=Cc1cccnc1Cl>>CN1CCN(c2ncccc2C=O)CC1 -US20020193614A1,2,COc1ccc(CNC(=O)c2cc(C#N)ccc2N[C@@H](C)CO)cc1OC.CS(=O)(=O)Cl>>COc1ccc(CNC(=O)c2cc(C#N)ccc2N[C@@H](C)COS(C)(=O)=O)cc1OC -US08173813B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNCCN1CCCc2cc(Br)ccc21>>CCN(CCN1CCCc2cc(Br)ccc21)C(=O)OC(C)(C)C -US07635715B2,6,CC(C)(C)OC(=O)C(C)(C)NC(=O)C1=C(O)c2cc(Cl)ccc2C2(CCOCC2)C1=O>>CC(C)(NC(=O)C1=C(O)c2cc(Cl)ccc2C2(CCOCC2)C1=O)C(=O)O -US08293927B2,3,CC(C)(C)[Si](C)(C)Oc1ccc(B2OB(c3ccc(O[Si](C)(C)C(C)(C)C)cc3)OB(c3ccc(O[Si](C)(C)C(C)(C)C)cc3)O2)cc1.COc1ccc(C=O)c(Br)c1O>>COc1ccc(C=O)c(-c2ccc(O[Si](C)(C)C(C)(C)C)cc2)c1O -US05916900,9,Cc1c(N)cc(F)c2cccnc12.S=C(Cl)Cl>>Cc1c(N=C=S)cc(F)c2cccnc12 -US20150232481A1,1,C=CCOC1(C)CCNCC1.CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(Cl)n2n1>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(C(=O)OCC)nn23)CC1 -US07704994B2,1,COC(=O)c1ccc(COc2ccc3c(c2)CCNCC3)cc1.O=C1CCCC1>>COC(=O)c1ccc(COc2ccc3c(c2)CCN(C2CCCC2)CC3)cc1 -US20120077812A1,3,CC(C)c1noc(N2CCC(COc3ccc(Br)cc3)CC2)n1.O=S(=O)(NCCO)c1ccc(B(O)O)cc1>>CC(C)c1noc(N2CCC(COc3ccc(-c4ccc(S(=O)(=O)NCCO)cc4)cc3)CC2)n1 -US20140235628A1,7,CC(C)(C)OC(=O)N1CCC(O)(C#Cc2ccc(F)c(C#N)c2)CC1>>CC(C)(C)OC(=O)N1CCC(O)(CCc2ccc(F)c(C#N)c2)CC1 -US20080292548A1,1,CNC.COC(=O)c1ccc(F)cc1Br>>COC(=O)c1ccc(N(C)C)cc1Br -US20110301176A1,1,C=O.CC(C)C1=C(C(=O)N2C[C@H](F)C[C@H]2C(=O)N2CCNC3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21>>CC(C)C1=C(C(=O)N2C[C@H](F)C[C@H]2C(=O)N2CCN(C)C3(CC3)C2)SC2=N[C@@](C)(c3ccc(Cl)nc3)[C@@H](c3ccc(Cl)c(F)c3)N21 -US06051712,1,COc1cc(COC2CN(C(=O)OC(C)(C)C)CCC2c2ccc(O)cc2)c(OC)c2ccccc12.N#Cc1cccc(CBr)c1>>COc1cc(COC2CN(C(=O)OC(C)(C)C)CCC2c2ccc(OCc3cccc(C#N)c3)cc2)c(OC)c2ccccc12 -US07348324B2,1,CC(=O)N1CCC(C(=O)N(CCCCl)c2cccc(Cl)c2)CC1.Cc1nnc(SC2CCNCC2)s1>>CC(=O)N1CCC(C(=O)N(CCCN2CCC(Sc3nnc(C)s3)CC2)c2cccc(Cl)c2)CC1 -US20050065187A1,8,NC(=O)C1CN(c2ccc(C3CCC(O)CC3)c(F)c2)C(=O)O1>>NC(=O)C1CN(c2ccc(C3CCC(=O)CC3)c(F)c2)C(=O)O1 -US07285558B2,2,CC(C)Cn1c(=O)n(C)c(=O)c2c(-c3cc(C(=O)O)cn3C)n(Cc3c[nH]c4ccc(Cl)cc34)nc21.CNC>>CC(C)Cn1c(=O)n(C)c(=O)c2c(-c3cc(C(=O)N(C)C)cn3C)n(Cc3c[nH]c4ccc(Cl)cc34)nc21 -US20050038035A1,6,COC(=O)c1sc(C)nc1-c1ccc(Cl)cc1>>Cc1nc(-c2ccc(Cl)cc2)c(C(=O)O)s1 -US20100144793A1,6,CC(=O)Nc1cc(C)n(C2CCCCO2)n1>>Cc1cc(N)nn1C1CCCCO1 -US05919795,2,O=C(Nc1ccc2c(c1)CCNC2)c1ccccc1-c1ccc(C(F)(F)F)cc1.O=S(=O)(Cl)c1cccc2ccccc12>>O=C(Nc1ccc2c(c1)CCN(S(=O)(=O)c1cccc3ccccc13)C2)c1ccccc1-c1ccc(C(F)(F)F)cc1 -US05006549,3,CCOC(=O)c1oc2cccc(OC)c2c1C.O=C(Cl)c1cccs1>>CCOC(=O)c1oc2c(C(=O)c3cccs3)ccc(OC)c2c1C -US20140179736A1,1,COc1cc2nccc(Cl)c2cc1OC.Nc1ccc(O)cc1>>COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC -US05723461,1,CSC[C@H](Nc1cc(F)ccc1[N+](=O)[O-])C(=O)O.C[O-]>>COc1ccc([N+](=O)[O-])c(N[C@@H](CSC)C(=O)O)c1 -US20100216746A1,6,CC(C)c1nc(Cl)c(COCc2ccccc2)[nH]1>>CC(C)c1nc(Cl)c(CO)[nH]1 -US04377578,7,O=C(c1ccc(Cl)cc1)c1ccccc1F>>OC(c1ccc(Cl)cc1)c1ccccc1F -US08173682B2,2,CCc1cc(-c2cncc(C(=O)O)c2)c(C)[nH]c1=O.NCc1ccc(S(N)(=O)=O)cc1>>CCc1cc(-c2cncc(C(=O)NCc3ccc(S(N)(=O)=O)cc3)c2)c(C)[nH]c1=O -US06569888B1,1,COC(=O)c1cc2c(OCCBr)cccc2n1Cc1ccc(Cl)c(Cl)c1.OCCN1CCNCC1>>COC(=O)c1cc2c(OCCN3CCN(CCO)CC3)cccc2n1Cc1ccc(Cl)c(Cl)c1 -US20090023918A1,2,CCO.O=C(O)C1CCC(N2CCCC2=O)CC1>>CCOC(=O)C1CCC(N2CCCC2=O)CC1 -US20050010068A1,3,Brc1ccccc1.C=CC(=O)OCCCC>>CCCCOC(=O)C=Cc1ccccc1 -US07514449B2,6,COC(=O)[C@@H]1CC[C@@H](C(=O)N(C)CCN(C)C)CC1>>CN(C)CCN(C)C(=O)[C@@H]1CC[C@@H](C(=O)O)CC1 -US08765730B2,3,CCS(=O)(=O)c1ccc(B(O)O)cc1.O/N=C(\CC(c1ccccc1)c1ccc(Br)cc1)c1ccncc1>>CCS(=O)(=O)c1ccc(-c2ccc(C(C/C(=N\O)c3ccncc3)c3ccccc3)cc2)cc1 -US20040058913A1,7,COc1cc2cc(C(=O)O)ccc2c(OC)c1OC>>COc1cc2cc(CO)ccc2c(OC)c1OC -US06548494B1,7,O=Cc1ccc2c3c1ccn3C(=O)CNC2>>O=C1CNCc2ccc(CO)c3ccn1c23 -US06924292B2,6,COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(NC(=O)C3CCN(C(=O)OC(C)(C)C)CC3)c1)=NC(C)(C)C2>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(NC(=O)C3CCNCC3)c1)=NC(C)(C)C2 -US20050234101A1,3,Brc1ccc(Br)nc1.C#C[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)C#Cc1ccc(Br)cn1 -US20060178384A1,1,COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.NCCN1CCCC1>>COc1ccc2c(c1)CCn1c-2cc(NCCN2CCCC2)nc1=O -US20110003820A1,2,O=C(O)c1cc2ncc(Cl)cn2n1.c1cc(-c2ccc3n2CCNC3)ncn1>>O=C(c1cc2ncc(Cl)cn2n1)N1CCn2c(ccc2-c2ccncn2)C1 -US20080058311A1,2,COC(=O)[C@H](CC(=O)O)NC(=O)OC(C)(C)C.c1ccc2c(c1)Sc1ccccc1C2=C1CCNCC1>>COC(=O)[C@@H](CC(=O)N1CCC(=C2c3ccccc3Sc3ccccc32)CC1)NC(=O)OC(C)(C)C -US06541466B2,2,C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O.NC1C(=O)NC(c2ccccc2)c2ccccc21>>C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)NC(c2ccccc2)c2ccccc21 -US20050027129A1,2,CC(=O)Cl.COc1ccc(C(=O)Nc2ccccc2)c2c1oc1ccc(N)cc12>>COc1ccc(C(=O)Nc2ccccc2)c2c1oc1ccc(NC(C)=O)cc12 -US20110275673A1,3,C#CCCCCCC.O=[N+]([O-])c1cc(Br)ccc1OCc1ccccc1>>CCCCCCC#Cc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1 -US05985281,9,O=c1ccn([C@@H]2O[C@H](CBr)[C@@H](O)[C@H]2OCc2ccccc2)c(=O)[nH]1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](OCc2ccccc2)[C@@H]1O -US05616711,2,CC(=O)OC(C)=O.NC(=S)CCc1ccco1>>CC(=O)NC(=S)CCc1ccco1 -US20040110811A1,1,CC1(C)NC(=O)N(C(=O)c2cccc3ccccc23)C1=O.N#Cc1ccc(CBr)cc1>>CC1(C)C(=O)N(C(=O)c2cccc3ccccc23)C(=O)N1Cc1ccc(C#N)cc1 -US20070270421A1,7,O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ncn1)N1CCN(CCN2CCCC2)CC1>>Nc1ccc(Oc2cc(NC(=O)N3CCN(CCN4CCCC4)CC3)ncn2)c(F)c1 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)cn3)c(F)c2)OC1(C)C.CS(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2Br)CC1>>CS(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)CC1 -US06162818,7,O=[N+]([O-])c1cccc2[nH]ccc12>>Nc1cccc2[nH]ccc12 -US20100055576A1,2,CC(C)(C)c1cc(O)cc(C(C)(C)C)c1.CCS(=O)(=O)Cl>>CCS(=O)(=O)Oc1cc(C(C)(C)C)cc(C(C)(C)C)c1 -US20070099915A1,3,C#CCN1CCOCC1.C[Si](C)(C)CCOCON1CCc2c(ncc3c2c(I)cn3Cc2ccc(F)cc2)C1=O>>C[Si](C)(C)CCOCON1CCc2c(ncc3c2c(C#CCN2CCOCC2)cn3Cc2ccc(F)cc2)C1=O -US20090047246A1,1,CCOC(=O)Cc1c[nH]c2ccccc12.COc1cccc(-c2ccc(Br)cc2)c1>>CCOC(=O)Cc1cn(-c2ccc(-c3cccc(OC)c3)cc2)c2ccccc12 -US07396844B1,2,COC(=O)c1ccc(Cc2ccncc2)cc1.N#Cc1cccc(OCCN)c1>>N#Cc1cccc(OCCNC(=O)c2ccc(Cc3ccncc3)cc2)c1 -US06229011B1,6,COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)NC(=O)c1ccc(-n2nnnc2NCc2cccc(O)c2)cc1Cl>>O=C(N[C@@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)C(=O)O)c1ccc(-n2nnnc2NCc2cccc(O)c2)cc1Cl -US08183381B2,1,CCc1cnc(N2CCC(n3cc(COS(C)(=O)=O)c(C(F)(F)F)n3)CC2)nc1.Oc1ccc(-n2cnnn2)cc1F>>CCc1cnc(N2CCC(n3cc(COc4ccc(-n5cnnn5)cc4F)c(C(F)(F)F)n3)CC2)nc1 -US20070037807A1,8,Cc1ccc(-c2c(CO)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1>>Cc1ccc(-c2c(C=O)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1 -US20100249123A1,2,CC(C)(C)C(=O)O.COc1ccc(C(=O)Nc2ccc(C3(CN)CCCC3)cc2)cc1OC>>COc1ccc(C(=O)Nc2ccc(C3(CNC(=O)C(C)(C)C)CCCC3)cc2)cc1OC -US20050124664A1,2,CCCCNc1ccccc1.O=C(Cl)c1cccc([N+](=O)[O-])c1>>CCCCN(C(=O)c1cccc([N+](=O)[O-])c1)c1ccccc1 -US20040214817A1,4,CC(C)(C)C(=O)CBr.NNC(N)=S>>CC(C)(C)c1csc(NN)n1 -US08354444B2,6,CC(C)(C)C[C@H]1N[C@H](C(=O)Nc2ccc(C(=O)OC(C)(C)C)cc2)[C@@H](c2cccc(Cl)c2F)[C@]1(C#N)c1ccc(Cl)cc1F>>CC(C)(C)C[C@H]1N[C@H](C(=O)Nc2ccc(C(=O)O)cc2)[C@@H](c2cccc(Cl)c2F)[C@]1(C#N)c1ccc(Cl)cc1F -US05070087,1,BrCc1ccccc1.COc1cc(C(O)C(=O)O)ccc1O>>COc1cc(C(O)C(=O)OCc2ccccc2)ccc1O -US20120289474A1,3,CCc1noc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(Br)cc32)n1.OB(O)c1ccccc1F>>CCc1noc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4F)cc32)n1 -US20060217380A1,1,CNCCCN(C)C.O=[N+]([O-])c1cc(Br)ccc1F>>CN(C)CCCN(C)c1ccc(Br)cc1[N+](=O)[O-] -US20060111351A1,1,C[C@H]1CNC[C@@H](C)O1.O=C(c1cccnc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(Br)cc1>>C[C@H]1CN(c2ccc(S(=O)(=O)Nc3ccc(Cl)cc3C(=O)c3cccnc3)cc2)C[C@@H](C)O1 -US20140155391A1,2,CN1CCN(CCN(c2cc(C(=O)O)ccc2C(F)(F)F)S(C)(=O)=O)CC1.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>CN1CCN(CCN(c2cc(C(=O)O[C@@H](Cc3c(Cl)c[n+]([O-])cc3Cl)c3ccc(OC(F)F)c(OCC4CC4)c3)ccc2C(F)(F)F)S(C)(=O)=O)CC1 -US06881733B1,1,CCOC(=O)C(C)Br.Oc1ccc(F)cc1Br>>CCOC(=O)C(C)Oc1ccc(F)cc1Br -US07812166B2,9,NC(=O)c1c(Cl)cncc1Cl>>N#Cc1c(Cl)cncc1Cl -US07635695B2,1,CCOC(=O)c1cnc(Cl)c([N+](=O)[O-])c1N.c1ccc(CNCc2ccccc2)cc1>>CCOC(=O)c1cnc(N(Cc2ccccc2)Cc2ccccc2)c([N+](=O)[O-])c1N -US20030065208A1,3,COc1ccc(Br)cc1.Cc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc(C)cc2)cc1 -US20140249120A1,1,CI.COCO[C@H]1CC[C@@]2(C)[C@H](C1)[C@H](O)C[C@H]1[C@@H]3CC[C@H](COCc4ccccc4)[C@@]3(C)CC[C@@H]12>>COCO[C@H]1CC[C@@]2(C)[C@H](C1)[C@H](OC)C[C@H]1[C@@H]3CC[C@H](COCc4ccccc4)[C@@]3(C)CC[C@@H]12 -US20150133512A1,6,COC(=O)C1(c2ccc(-c3ccc(-n4nnc(C)c4NC(=O)O[C@H](C)c4ccccc4)cc3)cc2)CC1>>Cc1nnn(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1NC(=O)O[C@H](C)c1ccccc1 -US20150141400A1,1,C=Cc1c(N)c(C(=O)OCC)cc(C(F)(F)F)c1C=O.CN(C(=O)OC(C)(C)C)[C@H]1CCCNC1>>C=Cc1c(N)c(C(=O)OCC)cc(C(F)(F)F)c1CN1CCC[C@H](N(C)C(=O)OC(C)(C)C)C1 -US20090076074A1,2,COc1cc2nccc(Oc3ccc(CC(=O)O)cc3)c2cc1OC.COc1ccc(Cn2nc(N(C)C(=O)OC(C)(C)C)cc2N)cc1OC>>COc1ccc(Cn2nc(N(C)C(=O)OC(C)(C)C)cc2NC(=O)Cc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1OC -US20150166483A1,2,COC(=O)c1cc(C(C)(C)C)cc(N)c1OC.O=C(Cl)Oc1ccccc1>>COC(=O)c1cc(C(C)(C)C)cc(NC(=O)Oc2ccccc2)c1OC -US20080194617A1,3,CCOC(=O)CP(=O)(OCC)OCC.Cc1cnc2c(ccn2-c2c(C=O)c(C)nn2C)c1>>CCOC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2cc(C)cnc21 -US06307056B1,6,COC(=O)c1ccc(-c2c(NC(=O)Cc3cccs3)ccc3c2/C(=C/c2[nH]ccc2OC)C(=O)N3)cc1>>COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(NC(=O)Cc3cccs3)c(-c3ccc(C(=O)O)cc3)c21 -US20060189663A1,1,COc1ccc(NC2=C(c3ccccc3)C(=O)NC2=O)cc1.OCc1ccccc1>>COc1ccc(NC2=C(c3ccccc3)C(=O)N(Cc3ccccc3)C2=O)cc1 -US20040110767A1,6,O=C(C1CCCCC1)N(Cc1ccc(OC2CCCCO2)cc1)c1ccc(OCCN2CCCC2)cc1>>O=C(C1CCCCC1)N(Cc1ccc(O)cc1)c1ccc(OCCN2CCCC2)cc1 -US20150025068A1,3,COC(=O)c1ccc(NS(=O)(=O)c2cc(Br)c(Cl)s2)cc1O.COc1ccc(F)cc1B(O)O>>COC(=O)c1ccc(NS(=O)(=O)c2cc(-c3cc(F)ccc3OC)c(Cl)s2)cc1O -US04563446,7,CCOC(=O)CCCC/C=C(\c1ccccc1)c1cccnc1>>OCCCCC/C=C(\c1ccccc1)c1cccnc1 -US05310724,1,CCNCC.O=[N+]([O-])c1ccc(Cl)nc1>>CCN(CC)c1ccc([N+](=O)[O-])cn1 -US08183246B2,1,COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1.N#CCCCCCO>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(OCCCCCC#N)c23)cc1 -US20100227863A1,1,C1COCCN1.COc1ccc(C2(O)C(=O)Nc3c2ccc(F)c3F)cc1>>COc1ccc(C2(N3CCOCC3)C(=O)Nc3c2ccc(F)c3F)cc1 -US06458781B1,2,CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)O.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US20120190677A1,6,COC(=O)c1ccc2c(c1)C(C)(C)CC(c1cccc(N3CCOCC3)c1)N2>>CC1(C)CC(c2cccc(N3CCOCC3)c2)Nc2ccc(C(=O)O)cc21 -US20120269803A1,2,C=CCC1(S(=O)(=O)Nc2c(Nc3ccc(I)cc3F)cc(F)cc2Oc2cccc(N)c2)CC1.CCS(=O)(=O)Cl>>C=CCC1(S(=O)(=O)Nc2c(Nc3ccc(I)cc3F)cc(F)cc2Oc2cccc(NS(=O)(=O)CC)c2)CC1 -US20140329807A1,1,N#Cc1cccc(-c2cnc3ccc(Cl)nn23)c1.N[C@H]1CC[C@H](O)CC1>>N#Cc1cccc(-c2cnc3ccc(NC4CCC(O)CC4)nn23)c1 -US20090253734A1,6,CC(C)(C)OC(=O)Nc1ccnc(Cl)c1C=O>>Nc1ccnc(Cl)c1C=O -US20150191432A1,2,CCOC(=O)COc1cccc2c1CCCC2.NCC(O)CN1CCc2ccccc2C1>>O=C(COc1cccc2c1CCCC2)NCC(O)CN1CCc2ccccc2C1 -US08349833B2,6,CCOC(=O)C(C)(C)CCCCC(c1ccccc1Cl)N1CCc2sccc2C1>>CC(C)(CCCCC(c1ccccc1Cl)N1CCc2sccc2C1)C(=O)O -US20100022491A1,6,O=C(OCc1ccccc1)N(CCC(=O)N(CCNCCc1ccc(O)c2[nH]c(=O)sc12)C1CCCCC1)CCc1cccc(F)c1>>O=C(CCNCCc1cccc(F)c1)N(CCNCCc1ccc(O)c2[nH]c(=O)sc12)C1CCCCC1 -US20130137660A1,1,C[C@@H](O)c1cccc([N+](=O)[O-])c1.Clc1cncc(Cl)n1>>C[C@@H](Oc1cncc(Cl)n1)c1cccc([N+](=O)[O-])c1 -US20150148353A1,2,CN1CCNCC1.COC(=O)C1C2CCC(O2)C1C(=O)O>>COC(=O)C1C2CCC(O2)C1C(=O)N1CCN(C)CC1 -US20130296312A1,3,CCOc1ccc(C(F)(F)F)cc1B(O)O.Clc1nc2c(Br)cccn2n1>>CCOc1ccc(C(F)(F)F)cc1-c1cccn2nc(Cl)nc12 -US20100298287A1,1,COC(=O)c1ccc(Cl)c2nc(Nc3ncc(Cl)cc3Cl)n(CCCCO)c12>>COC(=O)c1ccc(Cl)c2nc3n(c12)CCCCN3c1ncc(Cl)cc1Cl -US20040082611A1,2,C[C@H]1CN(S(=O)(=O)c2cc3cc(Cl)ccc3n2S(=O)(=O)c2ccccc2)C[C@@H](C)N1.O=C(Cl)c1ccc(Br)cc1>>CC1CN(S(=O)(=O)c2cc3cc(Cl)ccc3n2S(=O)(=O)c2ccccc2)CC(C)N1C(=O)c1ccc(Br)cc1 -US20110009454A1,7,CCCCCc1cccc(C#N)c1>>CCCCCc1cccc(CN)c1 -US04599344,1,CCCCCCCBr.OC1(CCc2ccc(Cl)cc2)CN2CCC1CC2>>CCCCCCC[N+]12CCC(CC1)C(O)(CCc1ccc(Cl)cc1)C2 -US20070249670A1,2,COC(=O)[C@@H](N)C1CCCCC1.Cc1cc(C(=O)O)c(NC(=O)Nc2c(Cl)cccc2Cl)s1>>COC(=O)[C@@H](NC(=O)c1cc(C)sc1NC(=O)Nc1c(Cl)cccc1Cl)C1CCCCC1 -US20100105894A1,2,N[C@@]12C(=O)OC[C@@H]1[C@@H]2c1ccccc1.O=S(=O)(Cl)c1ccc(-c2cc(C(F)(F)F)on2)s1>>O=C1OC[C@@H]2[C@H](c3ccccc3)[C@]12NS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)on2)s1 -US20150051395A1,7,COC(=O)c1cc(F)c(NS(=O)(=O)c2ccc(-c3cnc(C4=CCOCC4)nc3)cc2)cc1F>>COC(=O)c1cc(F)c(NS(=O)(=O)c2ccc(-c3cnc(C4CCOCC4)nc3)cc2)cc1F -US20140024634A1,1,COc1ccc(C=O)cc1.Oc1cc(CC(F)(F)F)c(-c2ccc3c(-c4nc5c([nH]4)CCNC5)n[nH]c3c2)cc1F>>COc1ccc(CN2CCc3[nH]c(-c4n[nH]c5cc(-c6cc(F)c(O)cc6CC(F)(F)F)ccc45)nc3C2)cc1 -US20150038437A1,1,CI.Cc1c(-c2ccc3c(c2)cc2n3CC(NC(=O)OC(C)(C)C)C2)nc(OCc2ccccc2)c(C(=O)OCc2ccccc2)c1OCc1ccccc1>>Cc1c(-c2ccc3c(c2)cc2n3CC(N(C)C(=O)OC(C)(C)C)C2)nc(OCc2ccccc2)c(C(=O)OCc2ccccc2)c1OCc1ccccc1 -US20110124665A1,1,COC(=O)COc1cccc(N)c1.Fc1ccc(-c2c(-c3ccc(Br)cc3)oc3ncnc(Cl)c23)cc1>>COC(=O)COc1cccc(Nc2ncnc3oc(-c4ccc(Br)cc4)c(-c4ccc(F)cc4)c23)c1 -US04343811,9,Cc1c(-c2ccc(Cl)cc2)c2cc(OC(C)(C)C(=O)O)ccc2n1C.N>>Cc1c(-c2ccc(Cl)cc2)c2cc(OC(C)(C)C(N)=O)ccc2n1C -US20100041722A1,8,OCc1cncn1C1Cc2ccccc2C1>>O=Cc1cncn1C1Cc2ccccc2C1 -US04840883,7,CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1c(Cl)cc(NC(=O)c2ccccc2)c(O)c1[N+](=O)[O-]>>CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1c(Cl)cc(NC(=O)c2ccccc2)c(O)c1N -US20150246912A1,1,CC(C)I.O=C(c1ccnc(Cl)c1)c1c[nH]c2ccncc12>>CC(C)n1cc(C(=O)c2ccnc(Cl)c2)c2cnccc21 -US08921397B2,2,CCCC(=O)O.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CCCC(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1 -US04808749,6,COC(=O)/C(Br)=C/[C@H]1[C@@H](C(=O)OC(C)(C)C)C1(C)C>>COC(=O)/C(Br)=C/[C@H]1[C@@H](C(=O)O)C1(C)C -US07291630B2,9,Fc1cccc(-c2cnc3[nH]c(Cl)cc3c2)c1>>Fc1cccc(-c2cnc3[nH]ccc3c2)c1 -US20150246922A1,3,Cc1c2n(c3c(Br)cc(Cl)cc13)CCCNC2=O.OB(O)c1ccc(F)c(F)c1>>Cc1c2n(c3c(-c4ccc(F)c(F)c4)cc(Cl)cc13)CCCNC2=O -US05296482,7,CNC(=O)CC1Cc2cc(OC)c(OC)cc2C1>>CNCCC1Cc2cc(OC)c(OC)cc2C1 -US20070244125A1,1,CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1.Cc1ccc(B(O)O)cc1>>Cc1ccc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(C(=O)N4CCN(C(C)C)CC4)ccc32)cc1 -US20120289500A1,2,CC(C)(C)CC(=O)O.Nn1nc(N2CCOCC2)c2ccccc2c1=O>>CC(C)(C)CC(=O)Nn1nc(N2CCOCC2)c2ccccc2c1=O -US05635197,3,CCCC[Sn](CCCC)(CCCC)c1cccs1.CN1C(=O)CC[C@]2(C)c3ccc(Br)cc3CC[C@@H]12>>CN1C(=O)CC[C@]2(C)c3ccc(-c4cccs4)cc3CC[C@@H]12 -US20100152210A1,9,CC(C)(C)OC(=O)N(c1ccc(F)cc1)c1nc(Cl)nc2c1ncn2Cc1ccccc1.NN>>CC(C)(C)OC(=O)N(c1ccc(F)cc1)c1nc(NN)nc2c1ncn2Cc1ccccc1 -US20110112120A9,1,CCCc1nc(CC)c(Br)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.COc1ccc(O)cc1OC>>CCCc1nc(CC)c(Oc2ccc(OC)c(OC)c2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US08003649B2,1,Cc1ccccc1C=O.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>Cc1ccccc1CN1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1 -US08853218B2,1,C=O.C[C@H]1CN(Cc2ccc(N)cc2)CCN1C(=O)OC(C)(C)C>>CNc1ccc(CN2CCN(C(=O)OC(C)(C)C)[C@@H](C)C2)cc1 -US06686389B2,7,Cc1cc2c(C(C)(C)C)c(O)ccc2o1>>CC1Cc2c(ccc(O)c2C(C)(C)C)O1 -US20100279871A1,1,CI.C[C@@H](Oc1ccc(OC(F)=Cc2ccccc2)cc1)C(=O)Nc1ccccc1F>>C[C@@H](Oc1ccc(OC(F)=Cc2ccccc2)cc1)C(=O)N(C)c1ccccc1F -US20070219210A1,2,CNOC.COc1ccc(-n2nc(C(=O)O)cc2-c2ccc(C)cn2)nn1>>COc1ccc(-n2nc(C(=O)N(C)OC)cc2-c2ccc(C)cn2)nn1 -US08940724B2,1,Cc1c(-c2ccncc2)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>Cc1c(-c2ccncc2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1 -US20140213571A1,6,CCOC(=O)C1Oc2ccc(Cl)nc2-c2cc3c(F)cccc3n21>>O=C(O)C1Oc2ccc(Cl)nc2-c2cc3c(F)cccc3n21 -US20090286778A1,7,CC(C)(C)OC(=O)NCCc1ccc([N+](=O)[O-])cc1I>>CC(C)(C)OC(=O)NCCc1ccc(N)cc1I -US20150152048A1,2,CC(C)(C)OC(=O)NC(=N)c1ccc(C(=O)O)cc1.COC(=O)Nc1ccc(-c2cnc([C@@H]3C[C@H](C4CCN(S(C)(=O)=O)CC4)CN3)[nH]2)cc1>>COC(=O)Nc1ccc(-c2cnc([C@@H]3C[C@H](C4CCN(S(C)(=O)=O)CC4)CN3C(=O)c3ccc(C(=N)NC(=O)OC(C)(C)C)cc3)[nH]2)cc1 -US05008266,1,Cc1ccc(-n2c(S)nc3ccccc3c2=O)cc1.ClCc1ccncc1>>Cc1ccc(-n2c(SCc3ccncc3)nc3ccccc3c2=O)cc1 -US20150158878A1,6,CCOC(=O)c1coc(-c2ccc3c(c2)CCO3)n1>>O=C(O)c1coc(-c2ccc3c(c2)CCO3)n1 -US20110009389A1,1,CC(C)(C)OC(=O)N1CCC(c2ncc[nH]2)CC1.CI>>Cn1ccnc1C1CCN(C(=O)OC(C)(C)C)CC1 -US20050019696A1,2,C=C(C)C(=O)Cl.OCc1ccc2cc(O)ccc2c1>>C=C(C)C(=O)OCc1ccc2cc(O)ccc2c1 -US20030139425A1,1,C[C@H]1CN(C(=O)COc2ccc(Cl)cc2)C[C@@H](C)N1.Fc1ccc(CBr)cc1>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2)C[C@@H](C)N1Cc1ccc(F)cc1 -US05411980,1,CCCCc1n[nH]c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.COC(=O)C(C)Br>>CCCCc1nn(C(C)C(=O)OC)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1 -US04426381,6,CCOC(=O)c1c2n(c3cc(Br)c(F)cc3c1=O)CCS2>>O=C(O)c1c2n(c3cc(Br)c(F)cc3c1=O)CCS2 -US20040067202A1,6,COCCOCCOCCOCCOCCOCCOCCOCCOCCOCc1ccccc1>>COCCOCCOCCOCCOCCOCCOCCOCCOCCO -US08329716B2,5,Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)C(F)(F)F -US06051718,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(C(C)CN)cc1OC1Cc2ccccc2C1>>COc1ccc(C(C)CNC(=O)OC(C)(C)C)cc1OC1Cc2ccccc2C1 -US07504410B2,5,Nc1ccc([N+](=O)[O-])cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc([N+](=O)[O-])cc1)C(F)(F)F -US04960769,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Oc1noc2c1CNCCC2>>CC(C)(C)OC(=O)N1CCCc2onc(O)c2C1 -US20110092505A1,5,CC(C)(C)OC(=O)N1CCN(c2cc([N+](=O)[O-])cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(c2cc([N+](=O)[O-])cc(-c3ccnc(N(C(=O)OC(C)(C)C)C4CCCCC4)c3)n2)CC1 -US05864045,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NCC(c1ccccc1)c1ccccc1 -US20030166650A1,5,CC(=O)c1ccc2c(c1)CCCN2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)c1ccc2c(c1)CCCN2C(=O)OC(C)(C)C -US07232834B2,5,C=C[C@H]1CNCC[C@H]1CCC(=O)c1ccnc2ccc(OC)cc12.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=C[C@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1CCC(=O)c1ccnc2ccc(OC)cc12 -US06534531B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1CCCNC1>>CC(C)(C)OC(=O)N1CCCC(C(=O)O)C1 -US05866685,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)CC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1 -US20110230462A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(CC(F)(F)F)C(=O)O>>CC(C)(C)OC(=O)NC(CC(F)(F)F)C(=O)O -US05994356,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)CC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1 -US08569494B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc(-c2nc[nH]n2)ccc1Br>>Cc1nc(-c2ncn(C(=O)OC(C)(C)C)n2)ccc1Br -US05919783,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=Cc1c[nH]c2cnc(-n3cncn3)cc12>>CC(C)(C)OC(=O)n1cc(C=O)c2cc(-n3cncn3)ncc21 -US05827863,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCn1nc(CC)c(C(=O)OC)c1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1>>CCCn1nc(CC)c(C(=O)OC)c1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1 -US07611909B1,5,O=Cc1ccc(Br)cc1.OCCO>>Brc1ccc(C2OCCO2)cc1 -US20120289481A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1CCCN1>>CC(C)(C)OC(=O)N1CCCC1=O -US20020151750A1,5,CCOC(=O)C(F)(F)F.CCOc1ccc(C[C@H](N)C(=O)O)cc1>>CCOc1ccc(C[C@H](NC(=O)C(F)(F)F)C(=O)O)cc1 -US08536209B2,5,CC(=O)c1cc(Cn2ncc([N+](=O)[O-])n2)on1.OCCO>>CC1(c2cc(Cn3ncc([N+](=O)[O-])n3)on2)OCCO1 -US05442047,5,CCOC(=O)C(F)(F)F.NC[C@H](O)C(=O)O>>O=C(O)[C@@H](O)CNC(=O)C(F)(F)F -US20110092511A1,5,NC1(c2ccc(-c3nc4ccn5c(-c6ncccn6)nnc5c4cc3-c3ccccc3)cc2)CC2(C1)OCCO2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NC1(c2ccc(-c3nc4ccn5c(-c6ncccn6)nnc5c4cc3-c3ccccc3)cc2)CC2(C1)OCCO2)C(F)(F)F -US20080255105A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(N)cc1Br>>Cc1ccc(NC(=O)OC(C)(C)C)cc1Br -US05665763,5,CC(=O)c1ccco1.OCCO>>CC1(c2ccco2)OCCO1 -US07153863B2,8,OC(c1ccccc1)c1nn2ccccc2c1-c1ccnc(NC2CCCC2)n1>>O=C(c1ccccc1)c1nn2ccccc2c1-c1ccnc(NC2CCCC2)n1 -US08993785B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]1C[C@@H](Cc2ccc(-c3ccccc3)cc2)NC1=O>>C[C@@H]1C[C@@H](Cc2ccc(-c3ccccc3)cc2)N(C(=O)OC(C)(C)C)C1=O -US06265604B1,8,CCC[C@](CCO)(CCc1ccccc1)OCOc1ccc(-c2ccccc2)cc1>>CCC[C@](CC=O)(CCc1ccccc1)OCOc1ccc(-c2ccccc2)cc1 -US04808595,8,NS(=O)(=O)c1cc2cnccc2o1.O=C(OO)c1cccc(Cl)c1>>NS(=O)(=O)c1cc2c[n+]([O-])ccc2o1 -US05994368,2,CC(=O)OC(C)=O.Cc1ccc2cccc(OCc3c(Cl)ccc(OCCN)c3Cl)c2n1>>CC(=O)NCCOc1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl -US08791103B2,2,C[C@H](N)c1nc2cc(Cl)ccc2[nH]1.O=C1CCN(c2ccc(C(=O)O)cc2C(F)(F)F)N1>>C[C@H](NC(=O)c1ccc(N2CCC(=O)N2)c(C(F)(F)F)c1)c1nc2cc(Cl)ccc2[nH]1 -US20090318431A1,2,CN1C(=O)OCc2cc(N)cc(F)c21.O=C(Cl)OCc1ccccc1>>CN1C(=O)OCc2cc(NC(=O)OCc3ccccc3)cc(F)c21 -US08207183B2,2,COC(=O)[C@@H]1[C@H](CCNCCc2ccccc2)CCN1[C@@H](C)c1ccccc1>>C[C@@H](c1ccccc1)N1CC[C@H]2CCN(CCc3ccccc3)C(=O)[C@H]21 -US05654299,2,CN.O=C(Cl)c1ccc(Br)cc1>>CNC(=O)c1ccc(Br)cc1 -US20090069287A1,2,O=C(Cl)OCc1ccccc1.OC1CCNC1>>O=C(OCc1ccccc1)N1CCC(O)C1 -US20120184561A1,2,CN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1.COc1ccc(-c2ccc3c(c2)ncn3-c2ccc(CC(=O)O)cc2)cc1>>COc1ccc(-c2ccc3c(c2)ncn3-c2ccc(CC(=O)Nc3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)cc2)cc1 -US05928999,2,Cn1nc(-c2ccc(Cl)c(S(=O)(=O)Cl)c2)c(Cl)c1OC(F)F.NC1CC1>>Cn1nc(-c2ccc(Cl)c(S(=O)(=O)NC3CC3)c2)c(Cl)c1OC(F)F -US20090312310A1,2,CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)O)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21.NN>>CC(C)C1=C(C(=O)N2CCC[C@H]2C(=O)NN)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21 -US07544637B2,2,CNC.N#Cc1c(OC(F)F)cccc1S(=O)(=O)Cl>>CN(C)S(=O)(=O)c1cccc(OC(F)F)c1C#N -US04616014,2,CCOC(=O)Cl.Cc1nc(NN)nnc1-c1ccccc1>>CCOC(=O)NNc1nnc(-c2ccccc2)c(C)n1 -US20020022648A1,2,Cn1nnc(N)n1.O=C(Cl)C1c2ccccc2Oc2ccccc21>>Cn1nnc(NC(=O)C2c3ccccc3Oc3ccccc32)n1 -US05508266,2,CC(=O)S[C@H](C(=O)O)C(C)C.CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)C(C)(C)N>>CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)C(C)(C)NC(=O)[C@@H](SC(C)=O)C(C)C -US08455521B2,8,C[Si](C)(C)CCS(=O)(=O)N1CCCC(CO)C1>>C[Si](C)(C)CCS(=O)(=O)N1CCCC(C=O)C1 -US20140163219A1,2,CC(C)C(=O)Cl.NC(N)=S>>CC(C)C(=O)NC(N)=S -US08257931B2,2,COC(=O)[C@@H](N)Cc1ccccc1.O=C(O)c1nc(-c2ccccc2)cs1>>COC(=O)C(Cc1ccccc1)NC(=O)c1nc(-c2ccccc2)cs1 -US08119661B2,2,CC(C)OC(=O)Cl.CC1(N2CCC(N3C(=O)N[C@@H]4CCCC[C@@H]43)CC2)CCNCC1>>CC(C)OC(=O)N1CCC(C)(N2CCC(N3C(=O)N[C@@H]4CCCC[C@@H]43)CC2)CC1 -US08476298B2,2,CC(C)(C)OC(=O)N1C[C@@H]2CC(O)C[C@@H]2C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1C[C@@H]2CC(OS(C)(=O)=O)C[C@@H]2C1 -US05580893,2,CC(Oc1cccc(Cl)c1)C(=O)O.NCCO[N+](=O)[O-]>>CC(Oc1cccc(Cl)c1)C(=O)NCCO[N+](=O)[O-] -US20120172359A1,2,CC(C)(C)OC(=O)NC1=N[C@@](c2cc(N)ccc2F)(C(F)F)COC1.Cc1cc(C#N)cnc1C(=O)O>>Cc1cc(C#N)cnc1C(=O)Nc1ccc(F)c([C@]2(C(F)F)COCC(NC(=O)OC(C)(C)C)=N2)c1 -US05629295,8,C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]1[C@@H]2C>>C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5CC(=O)CC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]1[C@@H]2C -US05185361,2,CC(C)COC(=O)Nc1cccc(Cn2ccc3cc(C(=O)O)ccc32)c1.NS(=O)(=O)c1ccccc1>>CC(C)COC(=O)Nc1cccc(Cn2ccc3cc(C(=O)NS(=O)(=O)c4ccccc4)ccc32)c1 -US20090181968A1,2,O=C(NCC1CCC1)c1nc(O)ccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12.O=S(=O)(Cl)CCC(F)(F)F>>O=C(NCC1CCC1)c1nc(OS(=O)(=O)CCC(F)(F)F)ccc1NC(=O)c1ccc(Cn2ccnn2)c2ccccc12 -US20140171430A1,2,Cc1cc(C)nc(N2CC3CNCC3C2)n1.Cc1ccc(-c2ncccn2)c(C(=O)O)n1>>Cc1cc(C)nc(N2CC3CN(C(=O)c4nc(C)ccc4-c4ncccn4)CC3C2)n1 -US05877193,2,Cc1ccc(S(=O)(=O)Cl)cc1.N#Cc1cccc(-c2csc(N)n2)c1>>Cc1ccc(S(=O)(=O)Nc2nc(-c3cccc(C#N)c3)cs2)cc1 -US20100093757A1,2,CS(=O)(=O)Cl.O=C1NCC[C@@H]1Oc1ncnc2c1cnn2-c1ccccc1Cl>>CS(=O)(=O)N1CC[C@H](Oc2ncnc3c2cnn3-c2ccccc2Cl)C1=O -US20110021500A1,2,CCNc1ccccc1.O=C(O)c1cc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)ncn1>>CCN(C(=O)c1cc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)ncn1)c1ccccc1 -US06248739B1,2,CCOC(=O)c1cn(N2CCOCC2)c2ccc(CN3CCOCC3)cc2c1=O.NCc1ccc(Br)cc1>>O=C(NCc1ccc(Br)cc1)c1cn(N2CCOCC2)c2ccc(CN3CCOCC3)cc2c1=O -US04470986,2,COC(=O)CCCCCc1cccc2cncn12.NO>>O=C(CCCCCc1cccc2cncn12)NO -US20030125344A1,2,NC(=O)c1ccccc1N.O=C(O)c1ccc(-c2ccccc2)c(F)c1>>NC(=O)c1ccccc1NC(=O)c1ccc(-c2ccccc2)c(F)c1 -US08288419B2,2,CC(F)(F)CCCCn1cc(N)cn1.O=C(O)c1ncoc1-c1ccccc1>>CC(F)(F)CCCCn1cc(NC(=O)c2ncoc2-c2ccccc2)cn1 -US20120309739A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ccnc(OS(=O)(=O)C(F)(F)F)c4c3-c3ccccc3)cc2)CCC1.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ccnc(-c5cn[nH]c5)c4c3-c3ccccc3)cc2)CCC1 -US07691836B2,3,CCCC[Sn](CCCC)(CCCC)c1cnccn1.C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(Br)cc3)C[C@]2(C)[C@H]1C(=O)C1CC1>>C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(-c4cnccn4)cc3)C[C@]2(C)[C@H]1C(=O)C1CC1 -US20150218143A1,2,CNOC.O=C(O)c1cc2cc(F)cc(F)c2s1>>CON(C)C(=O)c1cc2cc(F)cc(F)c2s1 -US20140171405A1,2,COC1CCNC1.COc1cc(OC)c(Cl)c(-c2cc3[nH]nc(-c4cnn(CC(=O)O)c4)c3cn2)c1Cl>>COc1cc(OC)c(Cl)c(-c2cc3[nH]nc(-c4cnn(CC(=O)N5CCC(OC)C5)c4)c3cn2)c1Cl -US05057506,2,O=C(Cl)c1ccccc1.O=C(O)[C@H]1C[C@@H](CP(=O)(O)O)CCN1>>O=C(O)[C@H]1C[C@@H](CP(=O)(O)O)CCN1C(=O)c1ccccc1 -US04598085,2,CS(=O)(=O)Cl.OCC(CC1CCCCC1)c1ccc(Cl)cc1Cl>>CS(=O)(=O)OCC(CC1CCCCC1)c1ccc(Cl)cc1Cl -US20140243286A1,2,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN)c1nnc(C)n1-2.C[Si](C)(O)c1ccc(C(=O)O)cc1>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCNC(=O)c1ccc([Si](C)(C)O)cc1)c1nnc(C)n1-2 -US20150025068A1,3,CC(=O)Nc1cccc(B(O)O)c1.COC(=O)c1ccc(NS(=O)(=O)c2cccc(Br)c2)cc1O>>COC(=O)c1ccc(NS(=O)(=O)c2cccc(-c3cccc(NC(C)=O)c3)c2)cc1O -US20130217666A1,3,C#CC(C)(C)O.NC(=O)c1nc2c(n1C(F)F)C1CC(C1)c1cc(F)c(I)cc1-2>>CC(C)(O)C#Cc1cc2c(cc1F)C1CC(C1)c1c-2nc(C(N)=O)n1C(F)F -US07317025B2,2,CC(=O)N1CCc2ccc(NC3CCN(Cc4ccccc4)CC3)cc21.O=C(O)/C=C/c1ccsc1>>CC(=O)N1CCc2ccc(N(C(=O)/C=C/c3ccsc3)C3CCN(Cc4ccccc4)CC3)cc21 -US05962473,2,CC(=O)c1ccc(C(=O)O)cc1.CN1CCC(c2c[nH]c3ccc(N)cc23)CC1>>CC(=O)c1ccc(C(=O)Nc2ccc3[nH]cc(C4CCN(C)CC4)c3c2)cc1 -US20090318435A1,2,COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)N.O=C(Cl)c1ccc(F)cc1>>COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)NC(=O)c1ccc(F)cc1 -US20100048731A1,8,COc1cc(CO)cc(OC)c1CCCCCCCCCCCCCCO[Si](C)(C)C(C)(C)C>>COc1cc(C=O)cc(OC)c1CCCCCCCCCCCCCCO[Si](C)(C)C(C)(C)C -US07026505B2,2,CCCC[C@@H](C)C[C@H](CO)CC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCC[C@@H](C)C[C@H](COS(=O)(=O)c1ccc(C)cc1)CC(=O)OC(C)(C)C -US20080312206A1,2,Cc1ncc(NC(=O)c2cc(N)ccc2C)s1.O=C(O)c1cc(F)cc(C(F)(F)F)c1>>Cc1ncc(NC(=O)c2cc(NC(=O)c3cc(F)cc(C(F)(F)F)c3)ccc2C)s1 -US07985755B2,2,Nc1nc(N)c2c(OCC3CCNCC3)cccc2n1.O=C(Cl)c1ccc(F)cc1F>>Nc1nc(N)c2c(OCC3CCN(C(=O)c4ccc(F)cc4F)CC3)cccc2n1 -US04021421,2,CN1C(=O)CN(N)C(c2ccccc2)c2cc(Cl)ccc21.O=C(O)CNC(=O)OCc1ccccc1>>CN1C(=O)CN(NC(=O)CNC(=O)OCc2ccccc2)C(c2ccccc2)c2cc(Cl)ccc21 -US07030128B2,3,CCCC[Sn](CCCC)(CCCC)c1cccc(Cl)n1.N#Cc1cccnc1Cl>>N#Cc1cccnc1-c1cccc(Cl)n1 -US04198421,2,CCO.O=C(O)c1ccccc1Oc1cccc(F)c1>>CCOC(=O)c1ccccc1Oc1cccc(F)c1 -US20150094319A1,2,N#Cc1ccnc(N)c1.O=C(Cl)c1ccc(Br)cc1>>N#Cc1ccnc(NC(=O)c2ccc(Br)cc2)c1 -US20120289522A1,3,C[Mg+].Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1CC(=O)CCc1ccccc1>>Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1CC(C)(O)CCc1ccccc1 -US20070054916A1,3,CCN(CC)CCCC(C)Nc1ncc2cc(Br)ccc2n1.Cc1ccnc(OCc2ccccc2)c1B1OC(C)(C)C(C)(C)O1>>CCN(CC)CCCC(C)Nc1ncc2cc(-c3c(C)ccnc3OCc3ccccc3)ccc2n1 -US20150099737A1,2,CC(=O)N1C2CCC1CNC2.CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)O)cn3)nc2n1C1CCCC1>>CC(=O)N1C2CCC1CN(C(=O)c1ccc(Nc3ncc4cc(C(=O)N(C)C)n(C5CCCC5)c4n3)nc1)C2 -US20080167321A1,2,CCCCCN.COC(=O)c1cncc(N2CCN(C(=O)c3cc(F)ccc3C(F)(F)F)CC2)c1>>CCCCCNC(=O)c1cncc(N2CCN(C(=O)c3cc(F)ccc3C(F)(F)F)CC2)c1 -US20030125371A1,3,Cn1ccc2ccc(Br)cc21.OB(O)c1ccc(C(F)(F)F)cc1>>Cn1ccc2ccc(-c3ccc(C(F)(F)F)cc3)cc21 -US20150266867A1,2,CC(C)(C)OC(=O)NCc1cnn(C[C@H]2NC(=O)[C@H]2N)n1.CC(C)(C)OC(=O)Nc1nc(/C(=N/OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)C(=O)O)cs1>>CC(C)(C)OC(=O)NCc1cnn(C[C@H]2NC(=O)[C@H]2NC(=O)/C(=N\OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)c2csc(NC(=O)OC(C)(C)C)n2)n1 -US20130261105A1,2,Clc1cc2c(nn1)CCNCC2.O=C(O)c1cc2ncc(Br)cn2n1>>O=C(c1cc2ncc(Br)cn2n1)N1CCc2cc(Cl)nnc2CC1 -US20150218096A1,3,COC(=O)c1ccc(B(O)O)c(F)c1.Ic1nn(C2CCCCO2)c2cccnc12>>COC(=O)c1ccc(-c2nn(C3CCCCO3)c3cccnc23)c(F)c1 -US06982348B2,2,NC(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1.O=C(O)c1ccc(F)c2ccccc12>>O=C(NC(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1)c1ccc(F)c2ccccc12 -US20060079548A1,2,Cc1sc2cc(Oc3ccnc4cc(C(=O)N5CC[C@@H](O)C5)sc34)ccc2c1C(=O)O.NCC1CC1>>Cc1sc2cc(Oc3ccnc4cc(C(=O)N5CC[C@@H](O)C5)sc34)ccc2c1C(=O)NCC1CC1 -US07265104B2,3,COc1ccc(N(C(=O)CN2C(=O)Cc3nnc(-c4ccccc4)n3-c3ccccc32)C(C)C)cn1.O=Cc1c[nH]c2ccccc12>>COc1ccc(N(C(=O)CN2C(=O)C(=Cc3c[nH]c4ccccc34)c3nnc(-c4ccccc4)n3-c3ccccc32)C(C)C)cn1 -US20110263584A1,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccc(F)cc2)OC1=O.N#Cc1ccc(Br)nc1>>C[C@@H](c1ccc(-c2ccc(C#N)cn2)cc1)N1CC[C@](CC(C)(C)O)(c2ccc(F)cc2)OC1=O -US07378526B2,3,BrC#Cc1ccccc1.C#CC(C)(C)O>>CC(C)(O)C#CC#Cc1ccccc1 -US20120277237A1,3,C#CCCN1C(=O)c2ccccc2C1=O.FCc1cccc(Br)n1>>O=C1c2ccccc2C(=O)N1CCC#Cc1cccc(CF)n1 -US20150099734A1,2,O=C(O)c1ccc2[nH]nnc2c1.O=C(OCc1cc(Cl)cc(Cl)c1)N1CCC2(CC1)CNC2>>O=C(OCc1cc(Cl)cc(Cl)c1)N1CCC2(CC1)CN(C(=O)c1ccc3[nH]nnc3c1)C2 -US20060235035A1,2,COc1cc([N+](=O)[O-])ccc1C(=O)O.NCCN1CCN(Cc2ccccc2)CC1>>COc1cc([N+](=O)[O-])ccc1C(=O)NCCN1CCN(Cc2ccccc2)CC1 -US20100222345A1,3,Brc1ccc2[nH]ccc2c1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccc3[nH]ccc3c2)cc1 -US20060276464A1,2,CC(C)c1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)Cl.N#Cc1cccc(C(=O)N2CCC(N)CC2)c1>>CC(C)c1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)NC1CCN(C(=O)c2cccc(C#N)c2)CC1 -US05618949,2,C/C=C/C(=O)Cl.O=C1N[C@H](c2ccccc2)CO1>>C/C=C/C(=O)N1C(=O)OC[C@H]1c1ccccc1 -US20050239656A1,2,CNC(c1cnccc1C(F)(F)F)C(C)C.O=C(Cl)Cc1ccccc1>>CC(C)C(c1cnccc1C(F)(F)F)N(C)C(=O)Cc1ccccc1 -US06900215B2,3,CC1(C)OB(c2cc(-c3ccccc3C#N)ccc2F)OC1(C)C.FC(F)c1ccn2c(Br)cnc2n1>>N#Cc1ccccc1-c1ccc(F)c(-c2cnc3nc(C(F)F)ccn23)c1 -US20150018345A1,2,NCCN.O=C(Cl)OCc1ccccc1>>NCCNC(=O)OCc1ccccc1 -US05189053,8,Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1CO>>Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1C=O -US20100130538A1,2,Cn1cc2c([C@@H]3C[C@H]3CN)cccc2n1.O=C(Cl)c1ccc(Br)cc1>>Cn1cc2c([C@@H]3C[C@H]3CNC(=O)c3ccc(Br)cc3)cccc2n1 -US08293772B2,2,C1CCNC1.Cc1ccc(-c2cn(CC(=O)O)nn2)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl>>Cc1ccc(-c2cn(CC(=O)N3CCCC3)nn2)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl -US07671080B2,2,CCC(N)CO.N#Cc1ccc2c(c1)cc(C(=O)O)n2Cc1cccc(OC(F)(F)F)c1>>CCC(CO)NC(=O)c1cc2cc(C#N)ccc2n1Cc1cccc(OC(F)(F)F)c1 -US05241064,2,CCOC(=O)[C@@H](CNCc1ccc(OC)cc1)[C@@H](C)O[Si](C)(C)C(C)(C)C>>COc1ccc(CN2C[C@@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)C2=O)cc1 -US08304557B2,2,Cc1cn(C)nc1C(=O)O.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)ccc1F>>Cc1cn(C)nc1C(=O)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)ccc1F -US20140371239A1,3,OB(O)c1ccncc1.OC(c1ccccc1)(c1ccccc1)C1CCN(CCCOc2ccc(Br)cc2)CC1>>OC(c1ccccc1)(c1ccccc1)C1CCN(CCCOc2ccc(-c3ccncc3)cc2)CC1 -US20150274777A1,2,CC1=C(C(=O)O)Cc2ccccc21.COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)N>>COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)NC(=O)C1=C(C)c2ccccc2C1 -US05834575,5,CCN(CCO)c1ccccc1.COCCl>>CCN(CCOCOC)c1ccccc1 -US20150018341A1,3,CCC(=O)c1ccccc1.O=C(c1ccc(O)cc1)c1ccc(O)cc1>>CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccccc1 -US06025375,3,COc1cccc(C=O)c1.C[Si](C)(C)OC1=CCCCC1>>COc1cccc(C(O)[C@H]2CCCCC2=O)c1 -US08895313B2,2,COc1ccc2nc(-c3ccc(N)cc3)sc2c1.O=C(O)c1ccc(Br)nc1>>COc1ccc2nc(-c3ccc(NC(=O)c4ccc(Br)nc4)cc3)sc2c1 -US20100256097A1,2,CC(=O)OC(C)=O.Cc1nc(Cl)ccc1N>>CC(=O)Nc1ccc(Cl)nc1C -US20070179173A1,3,CCOC(=O)CC(=O)OCC.COc1ccc(C=O)c2ccc(=O)n(C)c12>>CCOC(=O)C(=Cc1ccc(OC)c2c1ccc(=O)n2C)C(=O)OCC -US08163793B2,2,CN1CCC(C(=O)O)CC1.N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2)CC1>>CN1CCC(C(=O)N2C[C@H](S(=O)(=O)c3ccccc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)CC1 -US20140051679A1,3,COCCN1CCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.CO[C@@H](C(=O)Nc1ccc2[nH]nc(I)c2c1)c1ccccc1>>COCCN1CCC(Oc2ccc(-c3n[nH]c4ccc(NC(=O)[C@H](OC)c5ccccc5)cc34)cc2)CC1 -US20120027874A1,8,CN(Cc1ccc(CO)c(F)c1)C(=O)OC(C)(C)C>>CN(Cc1ccc(C=O)c(F)c1)C(=O)OC(C)(C)C -US06448243B1,1,CC(=O)NCc1ccc2c(c1)N(C1CCNCC1)CC2.Fc1ccc(CCCCBr)cc1>>CC(=O)NCc1ccc2c(c1)N(C1CCN(CCCCc3ccc(F)cc3)CC1)CC2 -US20100331309A1,1,CCOC(=O)CCCBr.COC(=O)c1cc(C)cc(C)c1NC(=O)OC(C)(C)C>>CCOC(=O)CCCN(C(=O)OC(C)(C)C)c1c(C)cc(C)cc1C(=O)OC -US03988446,2,CC(=O)C1(O)C=CC=CC1C(=O)Cl.CCCCCCCC(=O)OCC(O)COC(=O)CCCCCCC>>CCCCCCCC(=O)OCC(COC(=O)CCCCCCC)OC(=O)C1C=CC=CC1(O)C(C)=O -US05128062,1,ClCc1ccccc1.Oc1cccc(I)c1>>Ic1cccc(OCc2ccccc2)c1 -US20090039317A1,3,Brc1cccc(I)c1.OB(O)c1cc2ccccc2c2ccccc12>>Brc1cccc(-c2cc3ccccc3c3ccccc23)c1 -US20090149501A1,2,CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(C(=O)O)cc23)C1(C)C.NCCO>>CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(C(=O)NCCO)cc23)C1(C)C -US20100130473A1,1,Brc1cnc[nH]1.Clc1ccnc(Cl)n1>>Clc1nccc(-n2cncc2Br)n1 -US04713486,3,CCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1O>>CCCCCCC=Cc1ccccc1O -US20110009454A1,2,NCc1ccc(Oc2cccc(F)c2)cc1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1ccc(Oc2cccc(F)c2)cc1 -US20100286152A1,1,C1C[C@@H]2CNCCN2C1.O=C(O)C(Br)c1ccccc1Cl>>O=C(O)C(c1ccccc1Cl)N1CCN2CCC[C@@H]2C1 -US20140088076A1,2,Cc1ccncc1-c1ccc2cc(N)ncc2c1.O=C(O)C1C2COCC21>>Cc1ccncc1-c1ccc2cc(NC(=O)C3C4COCC43)ncc2c1 -US20060189661A1,3,Fc1ccc(Br)cc1-c1nc(-c2ccccn2)no1.OB(O)c1ccncc1>>Fc1ccc(-c2ccncc2)cc1-c1nc(-c2ccccn2)no1 -US08329682B2,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCOCC1)CCC2.O=C1Cc2cc(F)c(NCc3ccc(F)cc3)cc2N1>>Cc1c(/C=C2\C(=O)Nc3cc(NCc4ccc(F)cc4)c(F)cc32)[nH]c2c1C(=O)N(CCN1CCOCC1)CCC2 -US04337250,1,BrCCCCCCBr.O=C1NCCO1>>O=C1OCCN1CCCCCCBr -US20110112140A1,3,Cc1ccc(Br)cc1NCC(C)C.OB(O)c1ccc(F)cc1>>Cc1ccc(-c2ccc(F)cc2)cc1NCC(C)C -US20070099953A1,2,O=C(O)C(=O)c1cccs1.OC12CCN(CC1)CC2>>O=C(OC12CCN(CC1)CC2)C(=O)c1cccs1 -US20100292279A1,3,C#Cc1ccc(Cl)cc1.NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)cc1>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(C#Cc2ccc(Cl)cc2)cc1 -US20070149547A1,2,COC(=O)c1cccc(N)n1.Nc1ncc(Cl)nc1C(=O)O>>COC(=O)c1cccc(NC(=O)c2nc(Cl)cnc2N)n1 -US05081246,2,O=CO.O=S(=O)(NCCNCC=Cc1ccc(Cl)cc1)c1cccc2cnccc12>>O=CN(CC=Cc1ccc(Cl)cc1)CCNS(=O)(=O)c1cccc2cnccc12 -US20120029190A1,2,Cc1ccc(S(=O)(=O)N2CCC(C)C(O)C(N)C2)cc1.O=C(O)c1ccccn1>>Cc1ccc(S(=O)(=O)N2CCC(C)C(O)C(NC(=O)c3ccccn3)C2)cc1 -US07851473B2,2,N#Cc1ccc(NC(=O)OCC(Cl)(Cl)Cl)cn1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>N#Cc1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)cn1 -US20150246048A1,2,CN(c1ncnc2[nH]ccc12)[C@H]1C[C@H](N)C1.O=S(=O)(Cl)CC1CC1>>CN(c1ncnc2[nH]ccc12)[C@@H]1C[C@@H](NS(=O)(=O)CC2CC2)C1 -US07652022B2,2,CCc1ccc(N=C=O)cc1.Nc1ccc(Oc2ccnc(-c3nnn[nH]3)c2)cc1>>CCc1ccc(NC(=O)Nc2ccc(Oc3ccnc(-c4nnn[nH]4)c3)cc2)cc1 -US20100144755A1,2,CCCN.CCN(CC)CCCNc1nc(-c2cc(C(=O)O)cc(F)c2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1>>CCCNC(=O)c1cc(F)c(C)c(-c2nc(NCCCN(CC)CC)nc3c2ccc(=O)n3-c2c(F)cccc2F)c1 -US20100144739A1,3,COC(=O)c1nc(Br)cnc1N.OB(O)c1ccoc1>>COC(=O)c1nc(-c2ccoc2)cnc1N -US20110212956A1,2,CC(=O)OC(C)=O.NCCc1cccc(F)c1>>CC(=O)NCCc1cccc(F)c1 -US20080194549A1,2,CCc1ccc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CO)C(C)C)cc1OCCCOC.CS(=O)(=O)Cl>>CCc1ccc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2COS(C)(=O)=O)C(C)C)cc1OCCCOC -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.COc1ccc(Cl)cc1B(O)O>>CCCNC(=O)c1nnc2c(-c3cc(Cl)ccc3OC)cccc2c1N -US07947676B2,1,Cc1cc(Nc2ncnc3[nH]nc(OCCCl)c23)ccc1OCc1ccccn1.OC1CCNCC1>>Cc1cc(Nc2ncnc3[nH]nc(OCCN4CCC(O)CC4)c23)ccc1OCc1ccccn1 -US20060122234A1,2,COC(=O)c1ccc(-c2ccn(CC(=O)O)n2)s1.Nc1cnc2ccccc2c1>>COC(=O)c1ccc(-c2ccn(CC(=O)Nc3cnc4ccccc4c3)n2)s1 -US07638629B2,3,O=C(O)c1ccc(Cl)nc1.OB(O)c1ccc(C(F)(F)F)cc1>>O=C(O)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1 -US20140249024A1,3,CON(C)C(=O)c1sc(-c2cccnc2)nc1C(F)(F)F.C[Mg+]>>CC(=O)c1sc(-c2cccnc2)nc1C(F)(F)F -US20120178736A1,1,CCc1nc2ccccc2[nH]1.Cn1c(C=C2CN(C(=O)OC(C)(C)C)C2)nc2c(N3CCOCC3)nc(Cl)nc21>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=C3CN(C(=O)OC(C)(C)C)C3)n(C)c2n1 -US05885990,1,COC(=O)c1c(O)ccc2cc(C(=N)N)ccc12.O=C(O)c1ccc(NC2=NCCN2)cc1>>COC(=O)c1c(OC(=O)c2ccc(NC3=NCCN3)cc2)ccc2cc(C(=N)N)ccc12 -US20110046108A1,1,COc1ccc(CCl)cc1.O=[N+]([O-])c1cccc2[nH]nc(I)c12>>COc1ccc(Cn2nc(I)c3c([N+](=O)[O-])cccc32)cc1 -US04217284,1,C1=COCCC1.OC1C=CC(O)C1>>O[C@@H]1C=C[C@H](OC2CCCCO2)C1 -US20100324140A1,1,C1COCCN1.CC(C)CC(Oc1ccc(-c2ccc(C(C)C)cc2)c(C=O)c1)c1ccc(C(=O)NCCC(=O)O)cc1>>CC(C)CC(Oc1ccc(-c2ccc(C(C)C)cc2)c(CN2CCOCC2)c1)c1ccc(C(=O)NCCC(=O)O)cc1 -US06093345,2,CC[C@H](C)CCO.CS(=O)(=O)Cl>>CC[C@H](C)CCOS(C)(=O)=O -US20150057277A1,2,Nc1cccc(Oc2ccc3nccnc3c2)c1.O=C(O)c1cccc(F)c1>>O=C(Nc1cccc(Oc2ccc3nccnc3c2)c1)c1cccc(F)c1 -US06323370B1,1,CCCNCCC.O=C1CCCCC1>>CCCN(CCC)C1CCCCC1 -US05164392,1,C[C@H]1CNC[C@@H](C)N1.Nc1c(F)c(F)cc2c1c(=O)c(C(=O)O)cn2C1CC1>>C[C@H]1CN(c2cc3c(c(N)c2F)c(=O)c(C(=O)O)cn3C2CC2)C[C@@H](C)N1 -US20110160180A1,1,CCNC(=O)CN(CC)C(=O)c1ccc2[nH]c3c(c2c1)CC(C1CCOCC1)CC3.CCOC(=O)CI>>CCNC(=O)CN(CC)C(=O)c1ccc2c(c1)c1c(n2CC(=O)OCC)CCC(C2CCOCC2)C1 -US20120321964A1,2,CS(=O)(=O)Cl.OCCC1CCCC1>>CS(=O)(=O)OCCC1CCCC1 -US20110059957A1,2,CC(=O)OC(C)=O.CCN(CCN)c1ccc(Br)cc1>>CCN(CCNC(C)=O)c1ccc(Br)cc1 -US20050192310A1,3,CC(=O)N1Cc2cc(F)c(Cl)nc2C=Cc2ccccc21.CC1(C)OB(c2ccc(N3CCOCC3)nc2)OC1(C)C>>CC(=O)N1Cc2cc(F)c(-c3ccc(N4CCOCC4)nc3)nc2C=Cc2ccccc21 -US20150166549A1,1,Cc1ccc(-c2c(C(C)Br)oc(=O)c3ccccc23)cn1.Nc1ncnc2[nH]ncc12>>Cc1ccc(-c2c(C(C)n3ncc4c(N)ncnc43)oc(=O)c3ccccc23)cn1 -US20090105327A1,1,Nc1ccc([N+](=O)[O-])cc1[N+](=O)[O-].O=C1c2ccccc2COc2cc(F)ccc21>>O=C1c2ccccc2COc2cc(Nc3ccc([N+](=O)[O-])cc3[N+](=O)[O-])ccc21 -US06492377B1,1,CCn1c(=O)c2c(nc(C3CCCC3)n2Cc2ccccc2)n2nc(CBr)nc12.Oc1ccccc1>>CCn1c(=O)c2c(nc(C3CCCC3)n2Cc2ccccc2)n2nc(COc3ccccc3)nc12 -US04049701,1,COc1ccc2c(c1)C1(C)CCCCC(C2)C1=O.[NH4+]>>COc1ccc2c(c1)C1(C)CCCCC(C2)C1N -US05451592,3,Cc1ccc(B(O)O)cc1.N#Cc1ncccc1Br>>Cc1ccc(-c2cccnc2C#N)cc1 -US20150232481A1,1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(CI)nn23)CC1.C=CCc1cc(F)ccc1CO>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(COCc4ccc(F)cc4CC=C)nn23)CC1 -US06008365,1,CC(C)(C)OC(=O)CBr.OCCSc1ccccc1>>CC(C)(C)OC(=O)COCCSc1ccccc1 -US20110281884A1,3,CON(C)C(=O)c1cc(Cl)c2cncn2c1N1CCN(C(=O)OC(C)(C)C)CC1.C[Mg+]>>CC(=O)c1cc(Cl)c2cncn2c1N1CCN(C(=O)OC(C)(C)C)CC1 -US20140322355A1,2,CCc1nnc(-c2cc(C(=O)O)c(C)cc2C2CC(F)(F)C2)[nH]1.N#Cc1ccc(C2CCNCC2)cc1>>CCc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CC(F)(F)C2)[nH]1 -US05378844,2,CCCn1c(N)c(N)c(=O)n(CCC)c1=O.O=C(NC1(C(=O)O)CCCC1)C(F)(F)F>>CCCn1c(N)c(NC(=O)C2(NC(=O)C(F)(F)F)CCCC2)c(=O)n(CCC)c1=O -US06284785B1,2,Fc1ccc(C2CCCN2)cc1.O=S(=O)(Cl)c1ccc(CO)cc1>>O=S(=O)(c1ccc(CO)cc1)N1CCCC1c1ccc(F)cc1 -US20090143354A1,1,C=CC#N.CC(C)(C)OC(=O)N1CC[C@H](O)C1>>CC(C)(C)OC(=O)N1CC[C@H](OCCC#N)C1 -US05208247,2,CC(=O)NCc1ccccn1.CCCCCCCCCCCCCCOc1cc(C(=O)Cl)ccc1OC>>CCCCCCCCCCCCCCOc1cc(C(=O)N(Cc2ccccn2)C(C)=O)ccc1OC -US05635534,1,COC(=O)Cc1ccc(OCC(C)=O)cc1.NCC(O)c1cccc(F)c1>>COC(=O)Cc1ccc(OCC(C)NCC(O)c2cccc(F)c2)cc1 -US20100022536A1,2,CC(c1ccccc1C(F)(F)F)S(=O)(=O)Cl.CCOC(=O)CCc1ccc(S(=O)(=O)CCc2c(CCN)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1>>CCOC(=O)CCc1ccc(S(=O)(=O)CCc2c(CCNS(=O)(=O)C(C)c3ccccc3C(F)(F)F)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 -US20030225266A1,2,CC(C)S(=O)(=O)Cl.CC(CNS(=O)(=O)C(C)C)Oc1ccc(-c2cccc(N)c2)cc1>>CC(CNS(=O)(=O)C(C)C)Oc1ccc(-c2cccc(NS(=O)(=O)C(C)C)c2)cc1 -US08686022B2,2,CCC(=O)Cl.COc1c(N)cc(C(C)(C)C)cc1NC(=O)c1cc2cccc(CN3CCN(C(=O)C4CCCN4C)CC3)c2n1C>>CCC(=O)Nc1cc(C(C)(C)C)cc(NC(=O)c2cc3cccc(CN4CCN(C(=O)[C@@H]5CCCN5C)CC4)c3n2C)c1OC -US20130281438A1,2,CN.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>CNS(=O)(=O)c1ccccc1[N+](=O)[O-] -US20060287402A1,3,CC(C)(F)C[C@H](N[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)C(F)(F)F)C(=O)NC1(C#N)CC1.NC(=O)C1(c2ccc(Br)cc2)CC1>>CC(C)(F)C[C@H](N[C@@H](c1ccc(-c2ccc(C3(C(N)=O)CC3)cc2)cc1)C(F)(F)F)C(=O)NC1(C#N)CC1 -US20090247577A1,8,OC/C=C/c1cc(F)cc(F)c1>>O=C/C=C/c1cc(F)cc(F)c1 -US20120316147A1,2,CC(Oc1nc(C(=O)O)ccc1C1CC1)C(F)(F)F.Cc1nc(C(C)(C)N)no1>>Cc1nc(C(C)(C)NC(=O)c2ccc(C3CC3)c(OC(C)C(F)(F)F)n2)no1 -US06297266B1,2,CCCCOC(=O)COCCCN.Cc1nc(NC(=N)N)sc1C(=O)O>>CCCCOC(=O)COCCCNC(=O)c1sc(NC(=N)N)nc1C -US06797823B1,1,ClCCCCCBr.c1c[nH]nn1>>ClCCCCCn1ccnn1 -US07572809B2,1,COc1ccc2c(Cl)nc(Nc3cc(C)[nH]n3)cc2c1.Sc1ccc(Cl)cc1>>COc1ccc2c(Sc3ccc(Cl)cc3)nc(Nc3cc(C)[nH]n3)cc2c1 -US20130190290A1,2,Cc1ccc(N)cc1-n1ccn2nc(-c3cccnc3)cc12.N#Cc1cc(C(=O)O)cc(S(F)(F)(F)(F)F)c1>>Cc1ccc(NC(=O)c2cc(C#N)cc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 -US05426119,2,CCNCC.O=C(O)CCCC=C(c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1>>CCN(CC)C(=O)CCCC=C(c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 -US20150152108A1,2,Nc1cc(-c2cnco2)cc(-c2cnco2)c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cc(-c2cnco2)cc(-c2cnco2)c1)Oc1ccccc1 -US05817693,1,C=CCBr.CCCOc1ccc2c(c1)[C@@H](c1ccc(OC)cc1OCOC)[C@H](C(=O)O)[C@H]2c1ccc2c(c1)OCO2>>C=CCOC(=O)[C@@H]1[C@@H](c2ccc3c(c2)OCO3)c2ccc(OCCC)cc2[C@H]1c1ccc(OC)cc1OCOC -US08957070B2,2,CN(c1cccc2cc(-c3ncc(CCC(=O)O)s3)[nH]c12)S(=O)(=O)c1cccs1.CS(N)(=O)=O>>CN(c1cccc2cc(-c3ncc(CCC(=O)NS(C)(=O)=O)s3)[nH]c12)S(=O)(=O)c1cccs1 -US20150232469A1,1,ClCc1cc(Cl)ccc1Cl.Clc1nc2ccccc2nc1N1CCNCC1>>Clc1ccc(Cl)c(CN2CCN(c3nc4ccccc4nc3Cl)CC2)c1 -US06875765B2,6,CON(C)C(=O)C(CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1OCCc1c(O[Si](C(C)C)(C(C)C)C(C)C)ccc2ccccc12>>CON(C)C(=O)C(CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1OCCc1c(O)ccc2ccccc12 -US20060148858A1,6,COC(=O)Cc1c(OC)cccc1OCc1ccccc1>>COC(=O)Cc1c(O)cccc1OC -US04156738,2,CC(C)(C)N=C=O.CC(C)(N)C#N>>CC(C)(C)NC(=O)NC(C)(C)C#N -US07576222B2,6,CC#CCOc1ccc(S(=O)(=O)NC(Cc2c[nH]c3ccc(Br)cc23)C(=O)OCC)cc1>>CC#CCOc1ccc(S(=O)(=O)NC(Cc2c[nH]c3ccc(Br)cc23)C(=O)O)cc1 -US08278314B2,1,Cc1cc(Nc2ncnc3ccc(C=O)cc23)ccc1Oc1ccccc1.NN>>Cc1cc(Nc2ncnc3ccc(C=NN)cc23)ccc1Oc1ccccc1 -US20120040960A1,1,O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CNC1.O=C1CCC(O)(c2ccc(F)cc2)CC1>>O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(O)(c3ccc(F)cc3)CC2)C1 -US08034812B2,2,Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c(Cl)cc1F.O=C(O)c1cccc(C(F)(F)F)c1>>O=C(Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c(Cl)cc1F)c1cccc(C(F)(F)F)c1 -US20100272680A1,3,CC=C(C)[Sn](CCCC)(CCCC)CCCC.COC(=O)c1nc2c(C(F)(F)F)cc(Br)cn2c1Cl>>CC=C(C)c1cc(C(F)(F)F)c2nc(C(=O)OC)c(Cl)n2c1 -US20120121540A1,2,O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl.c1ccc(C2CCCN2)cc1>>O=C(c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl)N1CCCC1c1ccccc1 -US20110312945A1,1,O=S(=O)(c1ccccc1F)N1CCOCC1.SCc1ccccc1>>O=S(=O)(c1ccccc1SCc1ccccc1)N1CCOCC1 -US09000025B2,1,Brc1cccc(-c2ccccc2)c1.COC(=O)c1cccc(Sc2c(C)[nH]c3cc(Cl)ccc23)c1>>COC(=O)c1cccc(Sc2c(C)n(-c3cccc(-c4ccccc4)c3)c3cc(Cl)ccc23)c1 -US20080247964A1,1,O=C1CCC1.c1ccc(CN2CCC3(CCNC3)CC2)cc1>>c1ccc(CN2CCC3(CC2)CCN(C2CCC2)C3)cc1 -US20060154875A1,3,CCC1c2ccccc2-c2sc(Br)cc2N1S(=O)(=O)c1ccc(OC)cc1.CN(C)C=O>>CCC1c2ccccc2-c2sc(C=O)cc2N1S(=O)(=O)c1ccc(OC)cc1 -US20070135452A1,2,CCNCC.CCOC(=O)CN(c1ccc(OC)cc1)c1cccc2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12>>CCN(CC)C(=O)CN(c1ccc(OC)cc1)c1cccc2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12 -US20130005751A1,8,CC(C)(C)OC(=O)N1Cc2ncnc(Oc3ccc4c(ccn4C(=O)Nc4cc(C5(CO)CC5)on4)c3)c2C1>>CC(C)(C)OC(=O)N1Cc2ncnc(Oc3ccc4c(ccn4C(=O)Nc4cc(C5(C=O)CC5)on4)c3)c2C1 -USRE039679E1,2,CS(=O)(=O)Cl.OCCCc1c[nH]c2ccccc12>>CS(=O)(=O)OCCCc1c[nH]c2ccccc12 -US08829040B2,3,CCOC(=O)c1ccc(-n2cc(C#N)c3cc(Br)ccc32)cc1.COc1ccc(B(O)O)cc1>>CCOC(=O)c1ccc(-n2cc(C#N)c3cc(-c4ccc(OC)cc4)ccc32)cc1 -US20150191419A1,6,CC(C)(C)OC(=O)NCC(=O)CCC(=O)OCCCCCCCCCCCC(=O)O>>NCC(=O)CCC(=O)OCCCCCCCCCCCC(=O)O -US08846885B2,2,CC(CC(=O)Cl)CC(C)(C)C.Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1>>CC(CC(=O)Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1)CC(C)(C)C -US20070015786A1,1,Brc1ccccc1.O=C1CCc2ccccc2N1>>O=C1CCc2ccccc2N1c1ccccc1 -US05110818,1,CNc1nc(Cl)nc2[nH]cnc12.ClCc1ccccc1Cl>>CNc1nc(Cl)nc2c1ncn2Cc1ccccc1Cl -US20050222261A1,6,CCCCN(Cc1ccc(C(F)(F)F)cc1F)C(=O)COc1ccc(CCOc2ccccc2C(=O)OC)cc1>>CCCCN(Cc1ccc(C(F)(F)F)cc1F)C(=O)COc1ccc(CCOc2ccccc2C(=O)O)cc1 -US20100029615A1,6,COC(=O)C12CCCC(NC(=O)OC(C)(C)C)(C1)C2>>CC(C)(C)OC(=O)NC12CCCC(C(=O)O)(C1)C2 -US06545150B2,8,COC(=O)CN(c1ccccc1C)S(=O)(=O)c1ccccc1C(O)c1cc(OC)c2c(c1)OCO2>>COC(=O)CN(c1ccccc1C)S(=O)(=O)c1ccccc1C(=O)c1cc(OC)c2c(c1)OCO2 -US04985582,6,OCC(CO)(COCc1ccccc1)C1CCCCC1>>OCC(CO)(CO)C1CCCCC1 -US20050215487A1,1,CN1CCOCC1.COc1nc(Cl)nc(OC)n1>>COc1nc(OC)nc([N+]2(C)CCOCC2)n1 -US06645973B1,1,CCI.CCOC(=O)CN1CCC2(C=Cc3ccccc3O2)CC1c1cc(F)c(O)c(F)c1>>CCOC(=O)CN1CCC2(C=Cc3ccccc3O2)CC1c1cc(F)c(OCC)c(F)c1 -US20070179178A1,6,Cc1onc(-c2ccccc2)c1-c1cn2cc(NC(=O)OC(C)(C)C)ccc2n1>>Cc1onc(-c2ccccc2)c1-c1cn2cc(N)ccc2n1 -US05665754,2,CC(=O)OC(C)=O.COC(=O)[C@@H]1CNC[C@H]1c1ccc(OC)c(OC2CCCC2)c1>>COC(=O)[C@@H]1CN(C(C)=O)C[C@H]1c1ccc(OC)c(OC2CCCC2)c1 -US08217177B2,3,CC(O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1Cl.COc1cnc2c(NCc3nnc4ccc(Cl)nn34)ccnc2c1>>COc1cnc2c(NCc3nnc4ccc(-c5ccc(C(C)O)c(Cl)c5)nn34)ccnc2c1 -US20150259339A1,1,NC(=O)c1ccnc2c(O)ncnc12.N[C@H](CN1CCC1)c1ccc(C(F)(F)F)c(C(F)(F)F)c1>>NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(C(F)(F)F)c(C(F)(F)F)c3)ncnc12 -US20150225394A1,1,CC(C)(C)OC(=O)N1CC(CC#N)(N2CCC(=O)CC2)C1.N[C@@H]1C[C@H]1c1ccccc1>>CC(C)(C)OC(=O)N1CC(CC#N)(N2CCC(N[C@@H]3C[C@H]3c3ccccc3)CC2)C1 -US20110098300A1,2,C1COCCN1.O=C(O)c1ccc(S[C@@H]2C[C@@H](N3CCCCC3)C2)cc1>>O=C(c1ccc(S[C@@H]2C[C@@H](N3CCCCC3)C2)cc1)N1CCOCC1 -US07105544B2,2,CCCC(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.O=C(O)C1(c2ccc(Cl)cc2)CC1>>CCCC(=O)Nc1cccc(C2CCN(CCCNC(=O)C3(c4ccc(Cl)cc4)CC3)CC2)c1 -US05428038,1,CCOc1cc2ccc(=O)oc2cc1OCCCOS(C)(=O)=O.c1ccc(N2CCNCC2)cc1>>CCOc1cc2ccc(=O)oc2cc1OCCCN1CCN(c2ccccc2)CC1 -US20140329733A1,3,C#CC(C)O.CCC=CCCC=O>>CCC=CCCC(O)C#CC(C)O -US20100197711A1,2,CC(=O)c1ccc(-c2cccc(S(N)(=O)=O)c2)o1.O=C(O)CCCc1ccccc1>>CC(=O)c1ccc(-c2cccc(S(=O)(=O)NC(=O)CCCc3ccccc3)c2)o1 -US20130072679A1,1,CCS(=O)(=O)NCCOc1cncc(-c2ccc3c(c2)CCC(=O)N3C)c1.CI>>CCS(=O)(=O)N(C)CCOc1cncc(-c2ccc3c(c2)CCC(=O)N3C)c1 -US09115122B2,1,CCOc1ccc(/C=C2\SC(=O)NC2=O)cc1.ClCc1cccnc1>>CCOc1ccc(/C=C2\SC(=O)N(Cc3cccnc3)C2=O)cc1 -US20150038437A1,2,CN(Cc1ccccc1)[C@@H]1c2cc3cc(Br)ccc3n2C[C@@H]1CO.CS(=O)(=O)Cl>>CN(Cc1ccccc1)[C@@H]1c2cc3cc(Br)ccc3n2C[C@@H]1COS(C)(=O)=O -US05700801,6,COC(=O)COC1CCN(C(=O)[C@H](C)NC(=O)OC(C)(C)C)CC1>>COC(=O)COC1CCN(C(=O)[C@H](C)N)CC1 -US20110294780A1,1,O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CCNC[C@H]1F.OCCBr>>O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CCN(CCO)C[C@H]1F -US20060004046A1,3,CCOC(=O)c1ccc2ncc(C#N)c(Cl)c2c1.OB(O)c1cccnc1>>CCOC(=O)c1ccc2ncc(C#N)c(-c3cccnc3)c2c1 -US20150166563A1,5,COC(=O)C1(c2ccc(Br)cc2)CCC(=O)CC1.OCCO>>COC(=O)C1(c2ccc(Br)cc2)CCC2(CC1)OCCO2 -US20060063940A1,1,CN1CCNCC1.O=C1Nc2ccccc2C1=CNc1ccc(OCCCCI)cc1>>CN1CCN(CCCCOc2ccc(NC=C3C(=O)Nc4ccccc43)cc2)CC1 -US05670511,6,COc1ccc2[nH]cc(C3CCN(CCN4C(=O)c5cccc6cccc(c56)C4=O)CC3)c2c1>>O=C1c2cccc3cccc(c23)C(=O)N1CCN1CCC(c2c[nH]c3ccc(O)cc23)CC1 -US20100173889A1,3,CNC.O=C1CCN(Cc2ccccc2)CC1.[C-]#N>>CN(C)C1(C#N)CCN(Cc2ccccc2)CC1 -US20100120717A1,1,CCN.CCS(=O)(=O)c1cccc(-c2cc(CO)cc3[nH]c4ncc(C)cc4c23)c1>>CCNCc1cc(-c2cccc(S(=O)(=O)CC)c2)c2c(c1)[nH]c1ncc(C)cc12 -US20070072925A1,3,CCC[Mg+].CON(C)C(=O)c1cccc(Br)c1>>CCCC(=O)c1cccc(Br)c1 -US06274584B1,6,CN(CCc1ccccc1OCCO)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)OC(C)(C)C>>CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)CCc1ccccc1OCCO -US07625932B2,6,CCOC(=O)c1c(-c2ccc(-c3ccccc3C#N)cc2)c(C#N)c(CC)n1C>>CCc1c(C#N)c(-c2ccc(-c3ccccc3C#N)cc2)c(C(=O)O)n1C -US20120202806A1,1,CNC(C)C.COc1cnc(-c2ccccn2)nc1Cl>>COc1cnc(-c2ccccn2)nc1N(C)C(C)C -US20150051177A1,2,CN(c1ccc(C(F)(F)F)cc1)S(=O)(=O)c1ccc(C(=O)O)cc1.Nc1nc(-c2ccccn2)cs1>>CN(c1ccc(C(F)(F)F)cc1)S(=O)(=O)c1ccc(C(=O)Nc2nc(-c3ccccn3)cs2)cc1 -US20150158878A1,6,CCOC(=O)c1csc(NC(=O)Nc2ccccc2OC(F)(F)F)n1>>O=C(Nc1nc(C(=O)O)cs1)Nc1ccccc1OC(F)(F)F -US20050272763A1,1,CN(CCO)C(=O)C(=O)Nc1c(C(=O)C(C)(C)C)oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc12>>CN1CCN(c2c(C(=O)C(C)(C)C)oc3nc(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)cc23)C(=O)C1=O -US20150284382A1,2,CC(=O)O.CC(C)Nc1cc(Cl)ncc1C(=O)NCC[C@@H](C)N>>CC(=O)N[C@H](C)CCNC(=O)c1cnc(Cl)cc1NC(C)C -US08093239B2,1,COc1cc(N2CCN(S(C)(=O)=O)CC2)ccc1N.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>COc1cc(N2CCN(S(C)(=O)=O)CC2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1 -US20120022058A1,3,CC1(C)OB(c2ccc3c(c2)CNC(=O)N3)OC1(C)C.Cc1nc(N2N=C(Cl)C[C@@H]2C2CCCC2)ccc1C#N>>Cc1nc(N2N=C(c3ccc4c(c3)CNC(=O)N4)C[C@@H]2C2CCCC2)ccc1C#N -US20100222349A1,1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.CCCCc1cc(OC2CCNCC2)c2ncccc2c1>>CCCCc1cc(OC2CCN(CC3CCN(C(=O)OC(C)(C)C)CC3)CC2)c2ncccc2c1 -US20070010537A1,2,COC(=O)c1ccccc1N=C=O.Nc1cc(C(=O)N2CCCc3ccccc32)ccc1Cl>>COC(=O)c1ccccc1NC(=O)Nc1cc(C(=O)N2CCCc3ccccc32)ccc1Cl -US20070010520A1,1,Cn1nc(C(F)(F)F)c(C=O)c1Cl.Nc1nc(N2CCNCC2)cn2nc(-c3ccco3)nc12>>Cn1nc(C(F)(F)F)c(CN2CCN(c3cn4nc(-c5ccco5)nc4c(N)n3)CC2)c1Cl -US05736550,6,CC(C)(C)OC(=O)N(CCCN1C(=O)c2ccccc2C1=O)Cc1ccc(F)cc1>>CC(C)(C)OC(=O)N(CCCN)Cc1ccc(F)cc1 -US09079880B2,2,CO.O=C(O)C=Cc1cccc(Br)c1>>COC(=O)/C=C/c1cccc(Br)c1 -US20110028390A1,1,CC(=O)C=O.NNc1ccccn1>>CC(=O)C=NNc1ccccn1 -US20150072980A1,3,COc1cc2c(cc1N1CCOCC1)CCC2=O.O=Cc1cc(Cl)ccc1C(F)(F)F>>COc1cc2c(cc1N1CCOCC1)C/C(=C\c1cc(Cl)ccc1C(F)(F)F)C2=O -US20140200207A1,2,COc1cc(C(=O)O)ccc1N.NC1COC1>>COc1cc(C(=O)NC2COC2)ccc1N -US20110152248A1,3,Brc1cccc2c3c([nH]c12)C1CCN(CC1)C3.C=Cc1ccccn1>>C(=C/c1cccc2c3c([nH]c12)C1CCN(CC1)C3)\c1ccccn1 -US05736539,1,COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1.O=Cc1cccc2ccccc12>>COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1Cc1cccc2ccccc12 -US05039672,1,C=CC#N.Oc1ccccc1>>CC(C#N)Oc1ccccc1 -US20030078251A1,2,CCOC(=O)c1oc2ccc(N)cc2c1OC.COc1cccc([C@H]2O[C@H](CC(=O)O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC>>CCOC(=O)c1oc2ccc(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)COC(C)=O)C3=O)cc2c1OC -US04697033,6,CCC(C)Oc1ccc(OCCN2C(=O)c3ccccc3C2=O)cc1>>CCC(C)Oc1ccc(OCCN)cc1 -US20100029606A1,1,C1COCCN1.COc1cccc(-c2cc(NC(=O)CCCBr)n[nH]2)c1>>COc1cccc(-c2cc(NC(=O)CCCN3CCOCC3)n[nH]2)c1 -US06093731,1,CC(C)(C)OC(=O)CN(c1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.N=C(N)N>>CC(C)(C)OC(=O)CN(c1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1 -US08648088B2,1,CCN1NC(=O)CC1(C)C.Fc1ccc(I)cn1>>CCN1N(c2ccc(I)cn2)C(=O)CC1(C)C -US07915443B2,1,Cc1ccoc1C(=O)Nc1cccc(C#Cc2cncc(C(=O)N=S(=O)(CCCBr)c3ccccc3)c2)c1.OC1CCNC1>>Cc1ccoc1C(=O)Nc1cccc(C#Cc2cncc(C(=O)N=S(=O)(CCCN3CCC(O)C3)c3ccccc3)c2)c1 -US20140088078A1,6,COC(=O)c1c(NS(=O)(=O)c2ccccc2F)ccc2c1OC[C@@H]1OCC[C@H]21>>O=C(O)c1c(NS(=O)(=O)c2ccccc2F)ccc2c1OC[C@@H]1OCC[C@H]21 -US06977262B2,6,CN(CC1=C(C#N)C(c2cccc3nonc23)c2c[nH]nc2N1)C(=O)OC(C)(C)C>>CNCC1=C(C#N)C(c2cccc3nonc23)c2c[nH]nc2N1 -US20080269210A1,3,Clc1nc(N2CCOCC2)c2sc(I)cc2n1.O=C(O)c1cccc(B(O)O)c1>>O=C(O)c1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1 -US20130281392A1,3,Nc1cc(Cl)c(I)cc1N.OB(O)c1cccc(Cl)c1Cl>>Nc1cc(Cl)c(-c2cccc(Cl)c2Cl)cc1N -US20050026916A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1=N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1>>CC1=N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1C(=O)OC(C)(C)C -US06043242,6,CC(=O)OCc1nccc(OCCCCl)c1C>>Cc1c(OCCCCl)ccnc1CO -US20030105151A1,3,CCc1ccc2c(c1)CC(=O)N2.Cc1c(CCC(=O)O)c[nH]c1C=O>>CCc1ccc2c(c1)C(=Cc1[nH]cc(CCC(=O)O)c1C)C(=O)N2 -US20040121965A1,3,C=C[Sn](CCCC)(CCCC)CCCC.CN(C(=O)OC(C)(C)C)[C@](C)(C(=O)O)C(C)(C)c1ccc(Br)cc1>>C=Cc1ccc(C(C)(C)[C@@](C)(C(=O)O)N(C)C(=O)OC(C)(C)C)cc1 -US20140303168A1,6,CCOC(=O)c1cncc(-c2nnc(NCc3ccccn3)c3c(-c4ccccc4)cccc23)c1>>O=C(O)c1cncc(-c2nnc(NCc3ccccn3)c3c(-c4ccccc4)cccc23)c1 -US20110224186A1,6,CCOC(=O)/C(=N\OC(c1ccccc1)(c1ccccc1)c1ccccc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(O)/C(=N\OC(c1ccccc1)(c1ccccc1)c1ccccc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US20010044426A1,2,COC(CNc1ccc2c(c1)C(C#N)C2)OC.CS(=O)(=O)Cl>>COC(CN(c1ccc2c(c1)C(C#N)C2)S(C)(=O)=O)OC -US20080234384A1,1,O=C(O)c1c(Br)ccc2ccccc12.O=C(O)c1ccccc1S>>O=C(O)c1ccccc1Sc1ccc2ccccc2c1C(=O)O -US09120749B2,1,CN(C)[C@@H]1CC[C@@H](N)CC1.O=C(c1cnc2ccc(Br)cc2c1Cl)C1CC1>>CN(C)[C@@H]1CC[C@@H](Nc2c(C(=O)C3CC3)cnc3ccc(Br)cc23)CC1 -US20070232591A1,1,Clc1ncnc2c1CCNCC2.O=C(CCl)N1CCN(C2CCC2)CC1>>O=C(CN1CCc2ncnc(Cl)c2CC1)N1CCN(C2CCC2)CC1 -US07473705B2,6,COC(=O)c1ccc(OCCOc2c(C)cc(C(OCc3ccc(OC)cc3)(C(F)(F)F)C(F)(F)F)cc2C)cc1>>COC(=O)c1ccc(OCCOc2c(C)cc(C(O)(C(F)(F)F)C(F)(F)F)cc2C)cc1 -US20120028931A1,6,CC(C)(C)OC(=O)N1CCC(=Cc2nc(-c3cccc(Cl)c3)no2)CC1>>Clc1cccc(-c2noc(C=C3CCNCC3)n2)c1 -US20080269200A1,2,CCN=C=O.NC(=O)c1cc(-c2ccccc2)cc2c(C3CCNCC3)c[nH]c12>>CCNC(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccccc4)cc23)CC1 -US20040002524A1,2,CC(N)c1ccccc1.COc1ccc(-n2c(-c3ccc(C(=O)O)cc3)nc3ccccc32)cc1>>COc1ccc(-n2c(-c3ccc(C(=O)NC(C)c4ccccc4)cc3)nc3ccccc32)cc1 -US04663464,2,O=C(O)CCC1CCC(=O)N1>>O=C1CCC2CCC(=O)N12 -US20040266820A1,2,Cc1ccc(CCN=C=S)cc1.Cn1c(=O)cc(C(F)(F)F)c2cc(N)ccc21>>Cc1ccc(CCNC(=S)Nc2ccc3c(c2)c(C(F)(F)F)cc(=O)n3C)cc1 -US20080027076A1,1,CC(C)(C)c1cc(NC(=O)Nc2cccc(C#Cc3cncnc3Cl)c2)no1.CC(C)NCCCN>>CC(C)NCCCNc1ncncc1C#Cc1cccc(NC(=O)Nc2cc(C(C)(C)C)on2)c1 -US04847254,6,COC(=O)CC1Cc2cc(OC)ccc2O1>>COc1ccc2c(c1)CC(CC(=O)O)O2 -US06022492,3,Brc1cnc(Br)nc1.CCCCOc1ccc(B(O)O)cn1>>CCCCOc1ccc(-c2ncc(Br)cn2)cn1 -US20150141413A1,2,CC1(C)C(N)=N[C@](C)(c2cc(N)ccc2F)CS1(=O)=O.O=C(O)c1ccc(Cl)cn1>>CC1(C)C(N)=N[C@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CS1(=O)=O -US05328922,1,CI.O=[N+]([O-])c1ccc2cc[nH]c2c1>>Cn1ccc2ccc([N+](=O)[O-])cc21 -US20100130737A1,6,CCOC(=O)c1cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2s1>>O=C(O)c1cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2s1 -US08436008B2,1,CCOC(N)=O.CN1CCN(c2cc(N3CCc4ccc(Br)cc4C3)nc(N)n2)CC1>>CCOC(=O)Nc1ccc2c(c1)CN(c1cc(N3CCN(C)CC3)nc(N)n1)CC2 -US20110060013A1,1,Cc1cc(Nc2cc(N3CC[C@H](F)C3)cc(Cl)n2)[nH]n1.O=C(Nc1ccc(S)cc1)C1CC1>>Cc1cc(Nc2cc(N3CC[C@H](F)C3)cc(Sc3ccc(NC(=O)C4CC4)cc3)n2)[nH]n1 -US05324730,6,COc1ccc(C(Nc2nc3c(ncn3[C@@H]3C[C@H](COC(C)=O)[C@H]3COC(c3ccccc3)(c3ccc(OC)cc3)c3ccc(OC)cc3)c(=O)[nH]2)(c2ccccc2)c2ccc(OC)cc2)cc1>>COc1ccc(C(Nc2nc3c(ncn3[C@@H]3C[C@H](CO)[C@H]3COC(c3ccccc3)(c3ccc(OC)cc3)c3ccc(OC)cc3)c(=O)[nH]2)(c2ccccc2)c2ccc(OC)cc2)cc1 -US06353006B1,1,BrCC1CCCC1.NCCO>>OCCNCC1CCCC1 -US05155249,6,COC(=O)c1ccc(/C=C/c2cccc([Si](C)(C)C)c2)cc1>>C[Si](C)(C)c1cccc(C=Cc2ccc(C(=O)O)cc2)c1 -US20100204196A1,1,CC(C)I.COc1cc2c(cc1[N+](=O)[O-])CNCC2>>COc1cc2c(cc1[N+](=O)[O-])CN(C(C)C)CC2 -US07666888B2,2,CS(=O)(=O)N1Cc2ccccc2C12CCNCC2.Cc1ccc(-c2oncc2C(=O)Cl)cc1>>Cc1ccc(-c2oncc2C(=O)N2CCC3(CC2)c2ccccc2CN3S(C)(=O)=O)cc1 -US20100048549A1,2,CN(C)CCNC(=O)[C@@H](N)CSCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)c2ccccc12>>Cc1ccc(S(=O)(=O)N[C@@H](CSCc2ccccc2)C(=O)NCCN(C)C)c2ccccc12 -US07960425B2,1,CC(=O)c1nn(C)c(-c2ccc(C(F)(F)F)cc2)c1O.CCN(CC)C(=O)c1ccc(C(=O)NN)s1>>CCN(CC)C(=O)c1ccc(C(=O)NN=C(C)c2nn(C)c(-c3ccc(C(F)(F)F)cc3)c2O)s1 -US05998409,2,CCCCN1CCC(CO)CC1.O=C(O)c1c[nH]c2ccc(F)cc12>>CCCCN1CCC(COC(=O)c2c[nH]c3ccc(F)cc23)CC1 -US05849757,6,CC(C)(C)OC(=O)NC1(C2CC(=O)N(Cc3ccccc3)C2)CCC1>>NC1(C2CC(=O)N(Cc3ccccc3)C2)CCC1 -US04843087,1,BrCCCCCCBr.N#Cc1ccc(O)cc1>>N#Cc1ccc(OCCCCCCBr)cc1 -US20110082129A1,1,Cc1c(-c2cccnc2)[nH]c2ccc(Cl)cc12.N#Cc1ccc(CBr)cc1>>Cc1c(-c2cccnc2)n(Cc2ccc(C#N)cc2)c2ccc(Cl)cc12 -US06777418B2,3,Cc1cc2c(cc1Br)C(C)(C)CCC2(C)C.O=CN1CCCCC1>>Cc1cc2c(cc1C=O)C(C)(C)CCC2(C)C -US05616712,6,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CC(=O)N3Cc2ccccc2)cc1>>CC1(C)CC(=O)N(Cc2ccccc2)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 -US08765730B2,3,COC(=O)c1ccc(B(O)O)cc1.O/N=C(\CC(c1ccccc1)c1ccc(Br)cc1)c1ccncc1>>COC(=O)c1ccc(-c2ccc(C(C/C(=N\O)c3ccncc3)c3ccccc3)cc2)cc1 -US20040058903A1,2,Nc1ccc(OCCc2ccccn2)nc1.O=C(Cl)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(OCCc2ccccn2)nc1)c1ccccc1-c1ccc(C(F)(F)F)cc1 -US07368461B2,6,CN(C[C@@H](CCN1CCC(N2CCCCC2=O)CC1)c1ccc(Cl)c(Cl)c1)C(=O)OC(C)(C)C>>CNC[C@@H](CCN1CCC(N2CCCCC2=O)CC1)c1ccc(Cl)c(Cl)c1 -US08119647B2,3,COc1cccc(C=O)c1OCC1CC1.O=c1cc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)nc2sccn12>>COc1cccc(/C=C/c2cc(=O)n3ccsc3n2)c1OCC1CC1 -US08575204B2,2,Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1.NCC1CC1>>Cc1ccc(C(=O)NCC2CC2)cc1B1OC(C)(C)C(C)(C)O1 -US20090209522A1,6,CCOC(=O)c1csc(Oc2cc(C(C)(C)C)ccc2C)n1>>Cc1ccc(C(C)(C)C)cc1Oc1nc(C(=O)O)cs1 -US04179506,8,CC(=O)OO.c1ccc2c(c1)Oc1cccnc1O2>>[O-][n+]1cccc2c1Oc1ccccc1O2 -US20090221567A1,1,CC(C)(C)OC(=O)N1CCC(N(C(=O)CCl)[C@H]2CCCC[C@@H]2O)CC1>>CC(C)(C)OC(=O)N1CCC(N2C(=O)CO[C@H]3CCCC[C@@H]32)CC1 -US20120225886A1,2,C#CCCCC(=O)O.O=C1N[C@@H](Cc2ccccc2)CO1>>C#CCCCC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20080318925A1,3,COc1ncc(B(O)O)cc1F.Nc1c(C(=O)NC2CC2)nnc2c(I)c(F)ccc12>>COc1ncc(-c2c(F)ccc3c(N)c(C(=O)NC4CC4)nnc23)cc1F -US07312241B2,3,CCOP(=O)(CC#N)OCC.COc1cc(OC)cc(C(=O)c2cc(OC)ccc2OC)c1>>COc1cc(OC)cc(C(=CC#N)c2cc(OC)ccc2OC)c1 -US20140378446A1,6,COC(=O)/C=C/CN(C)[C@H]1CCOC1>>CN(C/C=C/C(=O)O)[C@H]1CCOC1 -US20030096856A1,1,COc1cc(CCl)cc(OC)c1OC.COc1ccc(S)cc1>>COc1ccc(SCc2cc(OC)c(OC)c(OC)c2)cc1 -US20040023989A1,6,CCOC(=O)c1cc(CC(C)C)[nH]n1>>CC(C)Cc1cc(C(=O)O)n[nH]1 -US07632857B2,3,COC(=O)c1ccc(Br)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US20100256356A1,6,COC(=O)c1nccn(Cc2ccccc2)c1=O>>O=C(O)c1nccn(Cc2ccccc2)c1=O -US20060247232A1,1,C[C@@H]1NCCO[C@@H]1C.FC(F)c1nc2ccccc2n1-c1nc(Cl)cc(Cl)n1>>C[C@@H]1OCCN(c2cc(Cl)nc(-n3c(C(F)F)nc4ccccc43)n2)[C@@H]1C -US08026365B2,2,CC(C)(C)OC(=O)N1CCC(N)(C#N)CC1.O=C(Cl)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCC(C#N)(NC(=O)c2ccc(Cl)cc2)CC1 -US07612067B2,3,CCC(CC)c1cc(C)nn2c(-c3sc(Br)cc3C#N)c(C)nc12.Ic1cccnc1>>CCC(CC)c1cc(C)nn2c(-c3sc(-c4cccnc4)cc3C#N)c(C)nc12 -US07576100B2,1,CCCC=C1CCNCC1.COc1ccc2c(c1)N(C[C@H](C)CI)C(=O)CO2>>CCCC=C1CCN(C[C@@H](C)CN2C(=O)COc3ccc(OC)cc32)CC1 -US06258829B1,8,Cc1nc2c(cc1CO)CCCCC2>>Cc1nc2c(cc1C=O)CCCCC2 -US08716484B1,1,Ic1ccc(-c2ccccc2)cc1.Nc1ccccc1-c1ccccc1>>c1ccc(-c2ccc(Nc3ccccc3-c3ccccc3)cc2)cc1 -US20100130737A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)c1ccc(O)cc1>>COC(=O)[C@@H](NC(=O)OC(C)(C)C)c1ccc(O)cc1 -US08557802B2,1,COc1ccc(CCl)cc1.O=C(O)CO>>COc1ccc(COC(=O)CO)cc1 -US08163909B2,6,CC(C)(C)OC(=O)NC(C(CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H](F)c1ccccc1>>CC(C)(C)OC(=O)NC(C(CO)O[Si](C)(C)C(C)(C)C)[C@H](F)c1ccccc1 -US20150218181A1,2,CNC.O=C(O)c1ccc2cnc(Br)cc2n1>>CN(C)C(=O)c1ccc2cnc(Br)cc2n1 -US03965141,3,CN(C)C=CC#N.CN(C)C=O>>CN(C)C=C(C#N)C=O -US05691315,6,COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)N1CCCCCC1>>CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O -US08058290B2,2,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.O=C=Nc1cc(C(F)(F)F)ccc1F>>CC1(C)OB(c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)OC1(C)C -US03948947,2,CCOC(=O)NN.O=C=NC1c2ccccc2Oc2ccccc21>>CCOC(=O)NNC(=O)NC1c2ccccc2Oc2ccccc21 -US20150182537A1,6,Cn1nccc1Nc1nccc(-c2cc(F)n3c(C(CCO[Si](C)(C)C(C)(C)C)Oc4ccccc4)nnc3c2)n1>>Cn1nccc1Nc1nccc(-c2cc(F)n3c(C(CCO)Oc4ccccc4)nnc3c2)n1 -US20100144755A1,2,CCCN.CCN(CC)CCCNc1nc(-c2cc(C(=O)O)ccc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1>>CCCNC(=O)c1ccc(C)c(-c2nc(NCCCN(CC)CC)nc3c2ccc(=O)n3-c2c(F)cccc2F)c1 -US20110275797A1,6,COc1ccccc1-c1ccc(C(=O)OC(C)(C)C)c(NC(=O)c2cc(N3CCCCC3)ccc2O)c1>>COc1ccccc1-c1ccc(C(=O)O)c(NC(=O)c2cc(N3CCCCC3)ccc2O)c1 -US20090005379A1,2,C1CCNC1.O=C([O-])c1cc2cc(OCCCN3CCCC3)cnc2[nH]1>>O=C(c1cc2cc(OCCCN3CCCC3)cnc2[nH]1)N1CCCC1 -US20140336106A1,3,C=C(C)[Mg+].CON(C)C(=O)[C@H](CC1=CCCC1)NC(=O)OC(C)(C)C>>C=C(C)C(=O)[C@H](CC1=CCCC1)NC(=O)OC(C)(C)C -US06071908,1,CS(=O)(=O)N1CC(CCl)c2ccc(N)cc21.O=Cc1ccc([N+](=O)[O-])cc1>>CS(=O)(=O)N1CC(CCl)c2ccc(NCc3ccc([N+](=O)[O-])cc3)cc21 -US05753664,1,Cc1ccc(C(=O)c2ccc(CBr)cc2)cc1.Cc1cccc2nc(S)n(C)c(=O)c12>>Cc1ccc(C(=O)c2ccc(CSc3nc4cccc(C)c4c(=O)n3C)cc2)cc1 -US06043248,3,C#C[Si](C)(C)C.CC(=O)c1cc(I)c(O)c(Cl)n1>>CC(=O)c1cc(C#C[Si](C)(C)C)c(O)c(Cl)n1 -US05556854,1,CSCCCl.Cn1c(=O)[nH]c2c(c1=O)CNCC2>>CSCCN1CCc2[nH]c(=O)n(C)c(=O)c2C1 -US20100069431A1,6,COC(=O)c1cc(OCc2ccccc2F)cc([N+](=O)[O-])c1>>O=C(O)c1cc(OCc2ccccc2F)cc([N+](=O)[O-])c1 -US05439955,3,C=O.CC(C)(C)CC(C)(C)c1ccc(O)c(-n2nc3ccccc3n2)c1.CCNCC>>CCN(CC)Cc1cc(C(C)(C)CC(C)(C)C)cc(-n2nc3ccccc3n2)c1O -US08247436B2,3,COC(=O)c1nc(Br)c(C(F)(F)F)cc1N.Cc1ccc(B(O)O)cn1>>COC(=O)c1nc(-c2ccc(C)nc2)c(C(F)(F)F)cc1N -US08399459B2,3,CC(C)(C)OC(=O)NC1=NC(C)(c2cccc(Br)c2)COC1.CC1(C)OB(c2cncc(C#N)c2)OC1(C)C>>CC(C)(C)OC(=O)NC1=NC(C)(c2cccc(-c3cncc(C#N)c3)c2)COC1 -US20090163490A1,3,COCOc1cc(Br)c(Cl)cc1OC.CSc1nc(Cl)c2c(C#N)cn(COCC[Si](C)(C)C)c2n1>>COCOc1cc(-c2nc(SC)nc3c2c(C#N)cn3COCC[Si](C)(C)C)c(Cl)cc1OC -US08188139B2,1,CS(=O)(=O)c1ccc(F)c(C(=O)O)c1.C[S-]>>CSc1ccc(S(C)(=O)=O)cc1C(=O)O -US20150183778A1,3,O=Cc1sccc1Br.OB(O)c1ccccc1>>O=Cc1sccc1-c1ccccc1 -US20130040930A1,1,Cc1cnc(N2CCN(C(=O)c3ccc(Br)nc3)CC2)c(C)c1.O=S1(=O)CCCCN1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCCCS4(=O)=O)nc3)CC2)c(C)c1 -US20130012485A1,6,O=C(NCC1(c2cccc(Cl)c2)CCC2(CC1)OCCO2)C(F)(F)F>>O=C1CCC(CNC(=O)C(F)(F)F)(c2cccc(Cl)c2)CC1 -US20090221555A1,1,Clc1ncc(Cl)c(Cl)n1.Nc1ccccc1-c1nc(C(F)(F)F)c[nH]1>>FC(F)(F)c1c[nH]c(-c2ccccc2Nc2nc(Cl)ncc2Cl)n1 -US08236950B2,1,Nc1ccc(O)cc1.O=C(Nc1ccc(Br)cc1)c1ccc(Cl)c([N+](=O)[O-])c1>>Nc1ccc(Oc2ccc(C(=O)Nc3ccc(Br)cc3)cc2[N+](=O)[O-])cc1 -US08084448B2,6,N#CCCCc1ccc(N2CC(=O)NS2(=O)=O)c(OCc2ccccc2)c1>>N#CCCCc1ccc(N2CC(=O)NS2(=O)=O)c(O)c1 -US06300330B1,6,CCOC(=O)c1ccc(-c2ccnnc2)cc1>>O=C(O)c1ccc(-c2ccnnc2)cc1 -US20040235822A1,2,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3C=O)cc1.Nc1ccc([C@@H](O)c2ccccn2)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([C@@H](O)c4ccccn4)cc2)CCN3C=O)cc1 -US20140275553A1,1,CC(C)(C)OC(=O)NC1CCNCC1.Fc1c(CBr)cc2scnc2c1-c1cccc(Cl)c1>>CC(C)(C)OC(=O)NC1CCN(Cc2cc3scnc3c(-c3cccc(Cl)c3)c2F)CC1 -US06624176B2,6,Cc1ccccc1-c1cc(NCc2ccccc2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ccccc1-c1cc(N)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US20140163009A1,1,O=C(NCC(F)(F)F)c1ccc(Br)cc1CO>>O=C1c2ccc(Br)cc2CN1CC(F)(F)F -US20110021479A1,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1.O=C(O)c1c[nH]c2c(-c3cc(F)ccc3OCC3CC3)ncnc12>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](NC(=O)c2c[nH]c3c(-c4cc(F)ccc4OCC4CC4)ncnc23)CC1 -US06552088B2,1,CC(C)(C(=O)Nc1ccccc1-c1ccccc1N)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CI>>CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1-c1ccccc1N -US20140128401A1,2,CCOC(=O)Cn1nc([N+](=O)[O-])cc1CNC(C)C>>CC(C)N1Cc2cc([N+](=O)[O-])nn2CC1=O -US20150158826A1,1,CO.Clc1cnc2ccc(Br)cc2n1>>COc1cnc2ccc(Br)cc2n1 -US08518972B2,1,O=C1CCC(N2C(=O)c3cccc(OCc4ccc(CBr)cc4)c3C2=O)C(=O)N1.c1ccc(C2CCNCC2)cc1>>O=C1CCC(N2C(=O)c3cccc(OCc4ccc(CN5CCC(c6ccccc6)CC5)cc4)c3C2=O)C(=O)N1 -US20070155970A1,7,CCOC(=O)CC(=O)/C=C/c1c(-c2ccc(F)cc2)c2ccccc2n1C(C)C>>CCOC(=O)C[C@H](O)/C=C/c1c(-c2ccc(F)cc2)c2ccccc2n1C(C)C -US08314138B2,2,Cc1nc(-c2cncc(N(C)Cc3ccc(F)cc3)n2)sc1C(=O)O.NCC1CC1>>Cc1nc(-c2cncc(N(C)Cc3ccc(F)cc3)n2)sc1C(=O)NCC1CC1 -US04386026,6,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCCCCCCN5C(=O)c6ccccc6C5=O)CC[C@]4(C)[C@H]3CC[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCCCCCCN)CC[C@]4(C)[C@H]3CC[C@]12C -US05091104,1,C=C(C)C.OCC(F)(F)F>>CC(C)(C)OCC(F)(F)F -US04021539,1,CC(O)CN.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CC(O)CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO -US07435815B2,2,CC(C)c1ccc(S(=O)(=O)Cl)nc1.Cc1ccc(N)cc1>>Cc1ccc(NS(=O)(=O)c2ccc(C(C)C)cn2)cc1 -US20110218177A1,6,COc1cc(CCOP(=O)(O)O)ccc1OC(=O)O[C@H](c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@H](C)N(Cc1cc(C(F)(F)F)ccc1-c1cc(C(C)C)c(F)cc1OC)C(=O)OC(C)(C)C>>COc1cc(CCOP(=O)(O)O)ccc1OC(=O)O[C@H](c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@H](C)[NH2+]Cc1cc(C(F)(F)F)ccc1-c1cc(C(C)C)c(F)cc1OC -US04668697,6,CC(=O)OCc1ccc2sc(S(N)(=O)=O)cc2c1>>NS(=O)(=O)c1cc2cc(CO)ccc2s1 -US20140018380A1,1,CC(C)c1noc(N2CCC(OS(C)(=O)=O)CC2)n1.Fc1cc2[nH]ccc2cc1Br>>CC(C)c1noc(N2CCC(n3ccc4cc(Br)c(F)cc43)CC2)n1 -US08129396B2,2,NC(=O)C(=C1Nc2ccc(C(=O)O)cc2S1)c1nccc(C(F)(F)F)n1.NCCCN1CCOCC1>>NC(=O)C(=C1Nc2ccc(C(=O)NCCCN3CCOCC3)cc2S1)c1nccc(C(F)(F)F)n1 -US20110184177A1,6,COC(=O)C(C)(C)NC(=O)c1ccc2ccccc2c1OCc1ccc(OC)nc1>>COc1ccc(COc2c(C(=O)NC(C)(C)C(=O)O)ccc3ccccc23)cn1 -US20090170790A1,7,C(=CC1OCCO1)c1cccc2cnccc12>>c1cc(CCC2OCCO2)c2ccncc2c1 -US20110092505A1,6,COC(=O)Nc1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCN(C(=O)OC(C)(C)C)CC2)c1>>COC(=O)Nc1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCNCC2)c1 -US20050288240A1,1,CC(C)(C)CN.Nc1c(Cl)ncnc1Cl>>CC(C)(C)CNc1ncnc(Cl)c1N -US20150018377A1,2,CC[C@@H](NC(=O)OC(C)(C)C)C(=O)O.Nc1ccc(Oc2cccc3c2C2(CC2)CO3)nc1>>CC[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc(Oc2cccc3c2C2(CC2)CO3)nc1 -US07893055B2,2,CC1(C)OCCn2c1nc(C(=O)O)c(OCc1ccccc1)c2=O.Cc1ncc(CN)s1>>Cc1ncc(CNC(=O)c2nc3n(c(=O)c2OCc2ccccc2)CCOC3(C)C)s1 -US20100069629A1,1,CCN1CCN(C(=O)c2ccc(F)c(Br)c2)CC1.COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4)cn2)cc1>>CCN1CCN(C(=O)c2ccc(F)c(N3CCc4c(-c5cnc(N(Cc6ccc(OC)cc6)Cc6ccc(OC)cc6)nc5)nc(N5CCOCC5)nc43)c2)CC1 -US04701556,1,COC(C)(OC)C(C)=O.[NH4+]>>COC(C)(OC)C(C)N -US20040138449A1,1,CNC[C@@H](O)c1cccnc1.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(CCl)cc21>>CN(Cc1cc2c(s1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C)C[C@@H](O)c1cccnc1 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.COc1ncc(B(O)O)cc1F>>CCCNC(=O)c1nnc2c(-c3cnc(OC)c(F)c3)cccc2c1N -US20080188484A1,3,CB1OB(C)OB(C)O1.CCOC(=O)c1cc2cc(OC)c(Br)cc2n1C(=O)OC(C)(C)C>>CCOC(=O)c1cc2cc(OC)c(C)cc2n1C(=O)OC(C)(C)C -US20130059853A1,1,CC(C)CBr.CCOc1ccc(-c2cccc3c2CCC3=O)c(O)c1OC>>CCOc1ccc(-c2cccc3c2CCC3=O)c(OCC(C)C)c1OC -US08354092B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C(CSCc1cccc(OCCOS(=O)(=O)c2ccc(C)cc2)c1)NC(=O)CN=[N+]=[N-]>>COC(=O)C(CSCc1cccc(OCCOS(=O)(=O)c2ccc(C)cc2)c1)N(C(=O)CN=[N+]=[N-])C(=O)OC(C)(C)C -US04960792,1,C=C(CBr)C(=O)OC(C)(C)C.c1ccc(CNCc2ccccc2)cc1>>C=C(CN(Cc1ccccc1)Cc1ccccc1)C(=O)OC(C)(C)C -US07332529B2,7,CCCCCCCCCCCOc1cc(OCCCCCCCCCCC)cc(C(=O)OC)c1>>CCCCCCCCCCCOc1cc(CO)cc(OCCCCCCCCCCC)c1 -US20020094453A1,7,O=C1CCCC1c1ccccn1>>OC1CCCC1c1ccccn1 -US05332750,1,CCCCc1cccc(=O)n1Cc1ccc(O)cc1.N#Cc1ccccc1CBr>>CCCCc1cccc(=O)n1Cc1ccc(OCc2ccccc2C#N)cc1 -US20040097736A1,1,C[S-].O=[N+]([O-])c1cnc2ccccc2c1NCCCl>>CSCCNc1c([N+](=O)[O-])cnc2ccccc12 -US20090227566A1,5,O=C(Nc1ccc(Cl)cn1)c1ccccc1NC(=O)c1ccc(N2CCCC2)cc1OC1CCNCC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc(Cl)cn1)c1ccccc1NC(=O)c1ccc(N2CCCC2)cc1OC1CCN(C(=O)C(F)(F)F)CC1 -US20070203155A1,1,CC(C)Oc1ccc(-c2nc(CBr)sc2Br)cc1.COC(=O)COc1ccc(O)cc1C>>COC(=O)COc1ccc(OCc2nc(-c3ccc(OC(C)C)cc3)c(Br)s2)cc1C -US04332611,2,CC(=O)OCc1ccccc1S(N)(=O)=O.O=C=Nc1nc(Cl)nc(Cl)n1>>CC(=O)OCc1ccccc1S(=O)(=O)NC(=O)Nc1nc(Cl)nc(Cl)n1 -US20070219187A1,3,C#CC1CCCN(C(=O)OC(C)(C)C)C1.Fc1ccc(I)cc1>>CC(C)(C)OC(=O)N1CCCC(C#Cc2ccc(F)cc2)C1 -US06284785B1,2,O=S(=O)(Cl)c1ccc(F)cc1.c1coc(C2CCCN2)c1>>O=S(=O)(c1ccc(F)cc1)N1CCCC1c1ccco1 -US20150239893A1,3,Nc1cccc(Br)c1F.OB(O)c1ncccc1Cl>>Nc1cccc(-c2ncccc2Cl)c1F -US20140249137A1,6,CCOC(=O)C(O[Si](C)(C)C(C)(C)C)c1ccc(-c2ncc(Cl)c(Nc3cc(C4CC4)[nH]n3)n2)s1>>CC(C)(C)[Si](C)(C)OC(C(=O)O)c1ccc(-c2ncc(Cl)c(Nc3cc(C4CC4)[nH]n3)n2)s1 -US20030109516A1,6,O=C(NCCCN1CC=C(c2ccc(Cl)cc2)CC1)C(F)(F)F>>NCCCN1CC=C(c2ccc(Cl)cc2)CC1 -US06114394,1,NCCCCO.O=Cc1ccccc1>>OCCCCNCc1ccccc1 -US07495007B2,6,COC(=O)C(C)(C)COc1ccc(Br)cc1[C@H]1NC(=O)C[C@@H](c2cc(Cl)ccc2C)[C@]12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(Cl)cc1C1CC(=O)NC(c2cc(Br)ccc2OCC(C)(C)C(=O)O)C12C(=O)Nc1cc(Cl)ccc12 -US07781443B2,1,O=C(O)CCl.OCCOCc1ccccc1>>O=C(O)COCCOCc1ccccc1 -US06620811B2,1,COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccnc(Br)c3)nc12.C[S-]>>COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccnc(SC)c3)nc12 -US20040235667A1,1,C[S-].N#Cc1cc(Cl)nc(Cl)c1>>CSc1cc(C#N)cc(Cl)n1 -US20060264460A1,7,N#Cc1cnc2c(Br)cc([N+](=O)[O-])cc2c1NC1CCCC1>>N#Cc1cnc2c(Br)cc(N)cc2c1NC1CCCC1 -US08309546B2,2,C[C@@H]1CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)CCN1.C[C@H](O)C(=O)O>>C[C@H](O)C(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)C[C@H]1C -US05705515,7,O=C(CBr)c1cncs1>>OC(CBr)c1cncs1 -US20150166480A1,6,CCOC(=O)c1ccc(-c2cnc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)cc1F>>O=C(O)c1ccc(-c2cnc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)cc1F -US20040019046A1,1,CC(C(=O)O)c1ccc(NC(=O)OCCCl)cc1>>CC(C(=O)O)c1ccc(N2CCOC2=O)cc1 -US06727257B1,6,c1ccc(CN2CCC(c3ccccn3)CC2)cc1>>c1ccc(C2CCNCC2)nc1 -US20130172384A1,2,CC(C)(C)OC(=O)NN.O=C(O)c1ccc(Br)c(F)c1>>CC(C)(C)OC(=O)NNC(=O)c1ccc(Br)c(F)c1 -US05541195,6,O=C(c1cccc2ccccc12)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1>>O=C(c1cccc2ccccc12)N1CC[C@H](NCc2ccnc3ccccc23)C[C@H]1Cc1ccccc1 -US20130303533A1,1,CN(C)C(=O)Cn1ccc2c(Cl)nc(S(=O)(=O)c3ccc(F)cc3)nc21.Nc1cc[nH]n1>>CN(C)C(=O)Cn1ccc2c(Nc3cc[nH]n3)nc(S(=O)(=O)c3ccc(F)cc3)nc21 -US08614226B2,3,CC(C)(C)OC(=O)N1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(Br)c2)c2cccnc2n1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cncc(-c4cc(-c5cc(Cl)ccc5F)nc5ncccc45)c3)cn2)CC1 -US20130172384A1,3,O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3Cl)n[nH]c2=O)C1.OB(O)c1ccc2cc[nH]c2c1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(-c4ccc5cc[nH]c5c4)cc3Cl)n[nH]c2=O)C1 -US06967216B2,1,CCOC(=O)CBr.O=C1NCCC1Cc1ccccc1>>CCOC(=O)CN1CCC(Cc2ccccc2)C1=O -US20110118230A1,3,Brc1cc2c(cn1)[nH]c1ncc(I)cc12.C[C@H]1CCC[C@@H](C)N1Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>C[C@H]1CCC[C@@H](C)N1Cc1ccc(-c2cnc3[nH]c4cnc(Br)cc4c3c2)cc1 -US20100298321A1,1,N#Cc1cc(S(N)(=O)=O)ccc1F.OCC1(F)CCN(C2COC2)CC1>>N#Cc1cc(S(N)(=O)=O)ccc1OCC1(F)CCN(C2COC2)CC1 -US20080275085A1,1,CC(=O)NCCCl.Cc1cc(F)ccc1[C@@H]1CNCC[C@H]1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(=O)NCCN1CC[C@@H](C(=O)N(C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](c2ccc(F)cc2C)C1 -US20100160255A1,6,Cc1c(-c2ccccc2)sc(NC(=O)OC(C)(C)C)c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1>>Cc1c(-c2ccccc2)sc(N)c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 -US20130184294A1,7,Cc1cccn2c(=O)c([N+](=O)[O-])c(Cl)nc12>>Cc1cccn2c(=O)c(N)c(Cl)nc12 -US06177474B1,3,CC(C)C(=O)Cl.Oc1cc(O)c(O)c(O)c1>>CC(C)C(=O)c1c(O)cc(O)c(O)c1O -US06534135B1,2,CC[C@H](C)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>CC[C@H](C)COS(=O)(=O)c1ccc(C)cc1 -US07319110B2,2,COC(=O)C(N)C(=O)OC.O=C(Cl)c1ccc(Cl)cc1>>COC(=O)C(NC(=O)c1ccc(Cl)cc1)C(=O)OC -US04874768,7,C=Cc1c2c3c(cccc3n1CCC)[C@H]1C[C@H](NC(=O)N(CC)CC)CN(C)[C@@H]1C2>>CCCn1c(CC)c2c3c(cccc31)[C@H]1C[C@H](NC(=O)N(CC)CC)CN(C)[C@@H]1C2 -US06888032B2,1,Cc1cc(C)cc(I)c1.SC1CCCCC1>>Cc1cc(C)cc(SC2CCCCC2)c1 -US05086070,1,CI.O=Cc1cccc2[nH]ccc12>>Cn1ccc2c(C=O)cccc21 -US05389651,1,CCC(C)Oc1ccc(OCCO)cc1.Clc1cccc(Cl)n1>>CCC(C)Oc1ccc(OCCOc2cccc(Cl)n2)cc1 -US08822453B2,1,Brc1ccccn1.Cn1c(=O)ccc2cc(OCCCCCNCCc3cccnc3)ccc21>>Cn1c(=O)ccc2cc(OCCCCCN(CCc3cccnc3)c3ccccn3)ccc21 -US20140249147A1,2,Nc1cccc(C(F)(F)F)n1.O=C(O)c1ccc2ncc(-c3cccc(Cl)c3)n2n1>>O=C(Nc1cccc(C(F)(F)F)n1)c1ccc2ncc(-c3cccc(Cl)c3)n2n1 -US20120208819A1,1,COc1ccc(CN)cc1.O=C(NCc1ccc(F)c(F)c1)c1c(I)ccnc1Cl>>COc1ccc(CNc2ccnc(Cl)c2C(=O)NCc2ccc(F)c(F)c2)cc1 -US20070208062A1,3,Brc1ccc(C2=NO[C@H](COCCN3CCOCC3)C2)nc1.CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C>>O=C1O[C@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NO[C@H](COCCN4CCOCC4)C3)nc2)c(F)c1 -US06531502B1,3,COc1c(C(C)C)cc(C=O)cc1C(C)C.O=C1Cc2ccc(O)cc2N1>>COc1c(C(C)C)cc(C=C2C(=O)Nc3cc(O)ccc32)cc1C(C)C -US07541365B2,1,CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1.CI>>COC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1 -US06964961B2,1,COC1CCN(C(=O)c2cc3nccc(Cl)c3s2)C1.Cc1cc2cc(N)ccc2[nH]1>>COC1CCN(C(=O)c2cc3nccc(Nc4ccc5[nH]c(C)cc5c4)c3s2)C1 -US20140296136A1,6,C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1CCCC1)NC(=O)O[C@@H]1CCC[C@H]1CCC=CCc1c(nc3ccccc3c1OCCCCO[Si](C)(C)C(C)(C)C)O2)C(=O)NS(=O)(=O)C1CC1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1CCCC1)NC(=O)O[C@@H]1CCC[C@H]1CCC=CCc1c(nc3ccccc3c1OCCCCO)O2)C(=O)NS(=O)(=O)C1CC1 -US05665329,6,CCOC(=O)Cn1ccnc1[N+](=O)[O-]>>O=C(O)Cn1ccnc1[N+](=O)[O-] -US20150182509A1,2,C1CCNC1.CCOC(=O)CCn1c2c(c3cc(Cl)ccc31)CN(C)CC2>>CN1CCc2c(c3cc(Cl)ccc3n2CCC(=O)N2CCCC2)C1 -US20140323390A1,6,CCCCCCCCCCNC(=O)OC[C@H](CSC[C@H](NC(=O)OCc1ccccc1)C(=O)NCCOCCOCCOCCC(=O)OC(C)(C)C)OC(=O)NCCCCCCCCCC>>CCCCCCCCCCNC(=O)OC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCOCCC(=O)OC(C)(C)C)OC(=O)NCCCCCCCCCC -US04939156,1,CI.O=c1[nH]cc(F)c(=O)[nH]1>>Cn1c(=O)[nH]cc(F)c1=O -US04072696,2,COC(=O)N=C=S.CSCSc1ccc(N)c([N+](=O)[O-])c1>>COC(=O)NC(=S)Nc1ccc(SCSC)cc1[N+](=O)[O-] -US20140094465A1,3,COc1ccc(B(O)O)c(F)c1.O=C(O)c1ccc(-c2ccc(Br)s2)cc1>>COc1ccc(-c2ccc(-c3ccc(C(=O)O)cc3)s2)c(F)c1 -US20020111332A1,1,CI.COc1cc(CN(C)C)cc(C)c1O>>COc1cc(C[N+](C)(C)C)cc(C)c1O -US20120088750A1,3,C#Cc1cncn1C.CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(Br)c2s1>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(C#Cc3cncn3C)c2s1 -US20050070582A1,2,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)Cl)c1>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc([N+](=O)[O-])ccc2Cl)CC1 -US20150175602A1,2,CC(C)Nc1nc2c(nc1N1CCC(C(=O)c3cc(Cl)ccc3F)CC1)CCNC2.CN(C)C(=O)Cl>>CC(C)Nc1nc2c(nc1N1CCC(C(=O)c3cc(Cl)ccc3F)CC1)CCN(C(=O)N(C)C)C2 -US20120115841A1,7,CC(O[Si](C)(C)C(C)(C)C)c1ncc(C=O)o1>>CC(O[Si](C)(C)C(C)(C)C)c1ncc(CO)o1 -US20110124642A1,2,Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O.O=C(O)Cc1cccnc1>>O=C(Cc1cccnc1)Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O -US08063234B2,3,C[Mg+].N#CC1CC1C(=O)c1ccc(Cl)cc1>>CC(O)(c1ccc(Cl)cc1)C1CC1C#N -US20150152096A1,10,CCOC(=O)C1=C(C)NC(c2ncccc2Cl)=NC1c1ccc(F)cc1Br.O=C1CCC(=O)N1Br>>CCOC(=O)C1=C(CBr)NC(c2ncccc2Cl)=NC1c1ccc(F)cc1Br -US20120225862A1,3,C#CCO.O=C(Nc1cccnc1)c1ccc(CNS(=O)(=O)c2ccc(I)cc2)cc1>>O=C(Nc1cccnc1)c1ccc(CNS(=O)(=O)c2ccc(C#CCO)cc2)cc1 -US06541505B1,1,CNC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO.N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(Cl)n4)cc3)cc12>>CN(C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO)c1nccc(-c2ccc(C(=O)NCCc3ccc4[nH]cc(C#N)c4c3)cc2)n1 -US06130217,6,COc1ccc([N+](=O)[O-])c2nc(C)sc12>>Cc1nc2c([N+](=O)[O-])ccc(O)c2s1 -US20030013886A1,1,C(=Cc1nc2ccccc2[nH]1)c1ccccc1.Clc1ccncn1>>C(=C/c1nc2ccccc2n1-c1ccncn1)\c1ccccc1 -US20090209522A1,7,COc1nc(N2CCNC2=O)nc(OC)c1[N+](=O)[O-]>>COc1nc(N2CCNC2=O)nc(OC)c1N -US20140105921A1,6,COc1ccc(COC(=O)CCC(=O)O[C@](C)(CI)C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCc2ccccc2)NC(=O)CN2CCOCC2)cc1>>CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@](C)(CI)OC(=O)CCC(=O)O -US20100216766A1,2,CNc1ccc(Oc2ccnc3cc(-c4nccn4C)sc23)c(F)c1.O=C(Cc1ccccc1)N=C=S>>CN(C(=S)NC(=O)Cc1ccccc1)c1ccc(Oc2ccnc3cc(-c4nccn4C)sc23)c(F)c1 -US20100216766A1,2,COCCN(Cc1cccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)c1)C(=O)OC(C)(C)C.O=C(Cc1ccccc1)N=C=S>>COCCN(Cc1cccc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4F)c3s2)c1)C(=O)OC(C)(C)C -US08147818B2,7,O=c1ccoc2cc(Br)ccc12>>O=C1CCOc2cc(Br)ccc21 -US20140336177A1,6,COC(=O)Cc1cc(C)c(-n2cnnn2)cn1>>Cc1cc(CC(=O)O)ncc1-n1cnnn1 -US20090111755A1,10,Cc1ccc2c(c1)c1ccccc1n2C(=O)OC(C)(C)C.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)n1c2ccccc2c2cc(CBr)ccc21 -US20100075968A1,2,CN1C(=O)N(c2ncc(F)cn2)CC1C(=O)O.NCc1ccc(Cl)cc1Cl>>CN1C(=O)N(c2ncc(F)cn2)CC1C(=O)NCc1ccc(Cl)cc1Cl -US06949648B2,1,Cc1nn(-c2ccccn2)c2nc3ccccc3c(Cl)c12.NC1CC1>>Cc1nn(-c2ccccn2)c2nc3ccccc3c(NC3CC3)c12 -US20150018341A1,1,C1CCNCC1.CCC(=C(c1ccc(O)cc1)c1ccc(OCCCl)cc1)c1ccc2oc(Cl)cc2c1>>CCC(=C(c1ccc(O)cc1)c1ccc(OCCN2CCCCC2)cc1)c1ccc2oc(Cl)cc2c1 -US05747490,6,COc1cc2nc(N3CCN(C(=O)OCc4ccccc4)[C@H](C(=O)NC(C)(C)C)C3)nc(N)c2cc1OC>>COc1cc2nc(N3CCN[C@H](C(=O)NC(C)(C)C)C3)nc(N)c2cc1OC -US05650428,6,CCOC(=O)c1cccc(NC(=O)C(Cn2ccnc2)NS(=O)(=O)c2ccc(Cl)cc2)c1>>O=C(O)c1cccc(NC(=O)C(Cn2ccnc2)NS(=O)(=O)c2ccc(Cl)cc2)c1 -US20110190280A1,7,O=[N+]([O-])c1ccc(OC2CCNCC2)c(F)c1>>Nc1ccc(OC2CCNCC2)c(F)c1 -US20070082890A1,2,CCOC(=O)Cn1cccc(Br)c1=O.NN>>NNC(=O)Cn1cccc(Br)c1=O -US06706878B2,3,Brc1cnc2c(c1)CC1(CN3CCC1CC3)O2.CCCC[Sn](CCCC)(CCCC)c1ccco1>>c1coc(-c2cnc3c(c2)CC2(CN4CCC2CC4)O3)c1 -US20140275524A1,3,Cc1cc(B2OC(C)(C)C(C)(C)O2)ccc1C=O.FC(F)(F)Oc1ccc(-n2cnc(Br)n2)cc1>>Cc1cc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)ccc1C=O -US20070213315A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc2c(c1)CCCC21CCNCC1>>CC(C)(C)OC(=O)N1CCC2(CCCc3ccccc32)CC1 -US07919506B2,6,COC1(c2ccc(C(F)(F)F)cc2CO[Si](C)(C)C(C)(C)C)CCCCC1>>COC1(c2ccc(C(F)(F)F)cc2CO)CCCCC1 -US20100113773A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1COC[C@H](COCc2ccccc2)N1>>CC(C)(C)OC(=O)N1C(=O)COC[C@@H]1COCc1ccccc1 -US05747498,1,C#Cc1cccc(N)c1.COC(=O)c1ccc2ncnc(Cl)c2c1>>C#Cc1cccc(Nc2ncnc3ccc(C(=O)OC)cc23)c1 -US06596741B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC(C)c1cc([N+](=O)[O-])ccc1Oc1ccc(Cl)c(Cl)c1>>CC(c1cc([N+](=O)[O-])ccc1Oc1ccc(Cl)c(Cl)c1)N(C)C(=O)OC(C)(C)C -US04908379,1,CCn1c(SC)nc(O)c(Br)c1=O.ClCc1ccc(C2CCCCC2)cc1>>CCn1c(SC)nc(OCc2ccc(C3CCCCC3)cc2)c(Br)c1=O -US20090326229A1,1,COc1ccccc1N.Clc1cccnc1Cl>>COc1ccccc1Nc1ncccc1Cl -US20080015146A1,2,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O.NNC(=O)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)NNC(=O)c1ccccc1 -US20140275154A1,1,CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(Cl)c(-c3cccc(C(=O)OC(C)(C)C)c3)cc12.NCC(F)(F)F>>CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)OC(C)(C)C)c3)cc12 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)nc3)c(F)c2)OC1(C)C.O=c1[nH]c(CS(=O)(=O)c2ccccc2Br)nc2ccccc12>>Nc1ncc(-c2ccc(-c3ccccc3S(=O)(=O)Cc3nc4ccccc4c(=O)[nH]3)cc2F)cn1 -US08536183B2,2,C[C@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CCN1.N#Cc1ccc(C(=O)O)cn1>>C[C@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CCN1C(=O)c1ccc(C#N)nc1 -US08178699B2,1,CI.COC(=O)c1sccc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1>>COC(=O)c1sccc1N(C)S(=O)(=O)c1ccc(C(C)(C)C)cc1 -US05710319,2,CCCN=C=O.CCOC(=O)c1ccccc1N>>CCCNC(=O)Nc1ccccc1C(=O)OCC -US20070088044A1,1,COc1cc(OC2CCN(C)CC2)c2c(Nc3ccc4[nH]ccc4c3)ncnc2c1.N#Cc1ccccc1CCl>>COc1cc(OC2CCN(C)CC2)c2c(Nc3ccc4c(ccn4Cc4ccccc4C#N)c3)ncnc2c1 -US20130245016A1,2,CC(C)c1cn(C)c2c(C(=O)O)cc(Br)cc12.Cc1cc(Cc2ccccc2)c(CN)c(=O)[nH]1>>Cc1cc(Cc2ccccc2)c(CNC(=O)c2cc(Br)cc3c(C(C)C)cn(C)c23)c(=O)[nH]1 -US20140073650A1,1,CC(C)N.FC(F)(F)c1ccc(-c2noc(CCl)n2)cc1>>CC(C)NCc1nc(-c2ccc(C(F)(F)F)cc2)no1 -US06288064B1,1,COc1ccc(CNc2nnc(Cl)c3ccc(C#N)cc23)cc1Cl.OC1CCNCC1>>COc1ccc(CNc2nnc(N3CCC(O)CC3)c3ccc(C#N)cc23)cc1Cl -US20070049618A1,2,Cn1cccc1C(=O)O.NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>Cn1cccc1C(=O)NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O -US20140213599A1,1,CC1Cn2c(cc(Cl)nc2=O)N1C.OCc1ccc(F)c(F)c1>>CC1Cn2c(cc(OCc3ccc(F)c(F)c3)nc2=O)N1C -US20090264445A1,1,CC(C)(O)Cn1ccc([N+](=O)[O-])n1.CI>>COC(C)(C)Cn1ccc([N+](=O)[O-])n1 -US07091357B2,7,COC(=O)CCCCC=C1CCC1>>OCCCCCC=C1CCC1 -US20110112151A1,8,Cn1cnnc1SCC(=O)C1(c2ccc(Cl)cc2)CCC1.O=C(OO)c1cccc(Cl)c1>>Cn1cnnc1S(=O)CC(=O)C1(c2ccc(Cl)cc2)CCC1 -US20140140956A1,1,CC(C)N.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCBr)c(-c4ccc(S(C)(=O)=O)cc4C)n3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCNC(C)C)c(-c4ccc(S(C)(=O)=O)cc4C)n3)nc2c1 -US05599813,1,CCOC(=O)CO.O=C(Nc1cc(Cl)cc(Cl)c1)C1=C(O)N2CCCN=C2S1>>CCOC(=O)COC1=C(C(=O)Nc2cc(Cl)cc(Cl)c2)SC2=NCCCN21 -US20080318925A1,3,CCCNC(=O)c1nnc2c(Br)cccc2c1N.OB(O)c1ccc2[nH]ccc2c1>>CCCNC(=O)c1nnc2c(-c3ccc4[nH]ccc4c3)cccc2c1N -US06133287,2,CN1CC=C(c2c[nH]c3ccc(C(F)(F)F)cc23)CC1.O=C(Cl)c1c(Cl)cccc1Cl>>CN1CC=C(c2cn(C(=O)c3c(Cl)cccc3Cl)c3ccc(C(F)(F)F)cc23)CC1 -US06458781B1,1,CC(C)C[C@@H](C=O)N(C)C(=O)OC(C)(C)C.NCCCC(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)C[C@@H](CNCCCC(c1ccc(F)cc1)c1ccc(F)cc1)N(C)C(=O)OC(C)(C)C -US07084149B2,1,CI.COc1ccc2cc(C(O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2c1>>COc1ccc2cc(C(OC)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2c1 -US20100121048A1,1,COC(=O)c1c[nH]c(-c2ccccc2)c1-c1ccccc1.COCCCBr>>COCCCn1cc(C(=O)OC)c(-c2ccccc2)c1-c1ccccc1 -US08975254B2,2,C[C@@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.O=C(O)c1csc(CN2CCCC2)n1>>C[C@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1csc(CN2CCCC2)n1 -US07888344B2,1,CC1(C)CC(=O)c2sc(N3CCOCC3Cc3c[nH]c4ccccc34)nc2C1.CI>>Cn1cc(CC2COCCN2c2nc3c(s2)C(=O)CC(C)(C)C3)c2ccccc21 -US05536718,7,O=C1Cc2cccn2-c2ccccc2N1>>c1ccc2c(c1)NCCc1cccn1-2 -US06197729B1,6,FC(F)C(F)C1CCC2(CC1)OCCO2>>O=C1CCC(C(F)C(F)F)CC1 -US20090318477A1,1,C[S-].Nc1ccc(I)cn1>>CSc1ccc(N)nc1 -US04126629,6,CC(=O)C(CCCCCCC(=O)OCc1ccccc1)CCCC(O)COCc1ccccc1>>CC(=O)C(CCCCCCC(=O)O)CCCC(O)COCc1ccccc1 -US07435815B2,2,CC(C)(C)c1ccc(S(=O)(=O)N(CC(=O)O)c2ccc3cn[nH]c3c2)cc1.CCNCc1cccc(C)n1>>CCN(Cc1cccc(C)n1)C(=O)CN(c1ccc2cn[nH]c2c1)S(=O)(=O)c1ccc(C(C)(C)C)cc1 -US04978778,1,C=COC(C)=O.CC(=O)O>>CC(=O)OC(C)OC(C)=O -US07741323B2,1,CCOC(=O)C1=C(c2ccccc2)c2ccc(O)cc2C1=O.OCCCc1ccccc1>>CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCCc3ccccc3)cc2C1=O -US20150175530A1,2,COC(=O)[C@@H](NC(=O)c1ccc(C#CC#CC(C)(O)CO)cc1)C(C)(C)N.NO>>CC(O)(C#CC#Cc1ccc(C(=O)N[C@H](C(=O)NO)C(C)(C)N)cc1)CO -US06391874B1,1,CCOC(=O)CBr.CS(=O)(=O)CCNC(=O)C(F)(F)F>>CCOC(=O)CN(CCS(C)(=O)=O)C(=O)C(F)(F)F -US07456170B2,2,CC(=O)OC(C)=O.Clc1ccc2c(c1)CNCc1nnc(N3CCC(c4ccccc4)CC3)n1-2>>CC(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2N2CCC(c3ccccc3)CC2)C1 -US05441969,3,Nc1nc2ccccc2n1-c1cccc(I)c1.OCc1cscc1B(O)O>>Nc1nc2ccccc2n1-c1cccc(-c2cscc2CO)c1 -US20060160858A1,2,Cn1cccc1C(=O)NN.O=C(O)c1ccccc1Nc1ccc2c(C=Cc3ccccn3)n[nH]c2c1>>Cn1cccc1C(=O)NNC(=O)c1ccccc1Nc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1 -US20140275536A1,2,COc1cccc(N)n1.Cc1cccc(C(=O)O)c1O>>COc1cccc(NC(=O)c2cccc(C)c2O)n1 -US04035495,7,CN(C)C(=O)CC1(C)Oc2ccccc2-n2cccc21>>CN(C)CCC1(C)Oc2ccccc2-n2cccc21 -US04777172,6,COCc1nccc(N2CCOCC2)n1>>OCc1nccc(N2CCOCC2)n1 -US04582833,1,CC(Br)C(=O)c1ccccc1.c1cc(-c2ccnc3nc(N4CCNCC4)nn23)ccn1>>CC(C(=O)c1ccccc1)N1CCN(c2nc3nccc(-c4ccncc4)n3n2)CC1 -US20110212943A1,6,COC(=O)c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1>>O=C(O)c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1 -US20100004238A1,6,CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H](N=[N+]=[N-])C1>>[N-]=[N+]=N[C@@H]1CNCC[C@H]1O -US06579881B2,1,CC(=O)NCc1ccc2c(c1)N(C1CCNCC1)CC2.Clc1ccc(CCBr)cc1>>CC(=O)NCc1ccc2c(c1)N(C1CCN(CCc3ccc(Cl)cc3)CC1)CC2 -US20040110742A1,1,C1CCNC1.O=C(O)Cc1ccc(Br)cc1>>O=C(O)Cc1ccc(N2CCCC2)cc1 -US20130281443A1,1,CNC(=O)c1ncsc1Br.Nc1cc(Cl)ncc1C(F)(F)F>>CNC(=O)c1ncsc1Nc1cc(Cl)ncc1C(F)(F)F -US20030149266A1,7,O=C(NCCCn1ccnc1)c1ccc([N+](=O)[O-])cc1>>Nc1ccc(C(=O)NCCCn2ccnc2)cc1 -US20120230951A1,3,CC(C)(C)OC(=O)N1CCOC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1.COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1ncc(-c2ccc(Br)cc2)[nH]1)C3>>COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1ncc(-c2ccc(-c4ccc(-c5cnc([C@@H]6COCCN6C(=O)OC(C)(C)C)[nH]5)cc4)cc2)[nH]1)C3 -US08436008B2,2,CS(=O)(=O)Cl.OCC1CCCC1>>CS(=O)(=O)OCC1CCCC1 -US06911450B1,2,O=C(Cl)c1ccccc1.OCCCCO>>O=C(OCCCCO)c1ccccc1 -US20090280106A1,1,COC(=O)c1nccnc1Br.NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)c1nccnc1NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1 -US20050026174A1,6,COC(=O)c1cc(Cl)c(NC(C)=O)c([N+](=O)[O-])c1OC>>COC(=O)c1cc(Cl)c(N)c([N+](=O)[O-])c1OC -USRE045670E1,1,COC(=O)C(C)S.Cc1ccc(NC(=O)Nc2ncc(Br)s2)c(C(=O)C2CCCC2)c1>>COC(=O)C(C)Sc1cnc(NC(=O)Nc2ccc(C)cc2C(=O)C2CCCC2)s1 -US06803486B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccccc1N>>CC(C)(C)OC(=O)NCCc1ccccc1N -US20150072976A1,6,COC(=O)c1ccc(-c2nc(CS(=O)(=O)C3CCN(C(=O)OC(C)(C)C)CC3)c(C)o2)cc1>>Cc1oc(-c2ccc(C(=O)O)cc2)nc1CS(=O)(=O)C1CCN(C(=O)OC(C)(C)C)CC1 -US04965260,1,C=CCOC(=O)O[C@H](C)[C@H]1C(=O)N(C(C(=O)OCC=C)=P(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@H]1S.O=C(Cl)COc1ccc(F)cc1>>C=CCOC(=O)O[C@H](C)[C@H]1C(=O)N(C(C(=O)OCC=C)=P(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@H]1SC(=O)COc1ccc(F)cc1 -US20140088076A1,1,Fc1ccc(Cl)c(-c2cnc3cc(Br)ncc3c2)c1.NC(=O)C1CC1>>O=C(Nc1cc2ncc(-c3cc(F)ccc3Cl)cc2cn1)C1CC1 -US04402957,2,COC(CN=C=S)OC.Oc1ccc(N2CCNCC2)cc1>>COC(CNC(=S)N1CCN(c2ccc(O)cc2)CC1)OC -US20140051706A1,2,CC(C)CC(N=C=O)C(=O)OC(C)(C)C.C[C@H]1C2N(C(=O)CN(C)N2C(=O)NCc2ccccc2)[C@@H](Cc2ccc(O)cc2)C(=O)N1Cc1cccc2cccnc12>>CC(C)CC(NC(=O)Oc1ccc(C[C@H]2C(=O)N(Cc3cccc4cccnc34)[C@@H](C)C3N2C(=O)CN(C)N3C(=O)NCc2ccccc2)cc1)C(=O)OC(C)(C)C -US20040058978A1,6,CCOC(=O)Cc1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1>>O=C(O)Cc1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1 -US20040102450A1,10,Cc1ccc2c(Cl)ncnc2c1.O=C1CCC(=O)N1Br>>Clc1ncnc2cc(CBr)ccc12 -US04950674,6,CCOC(=O)Cc1ccc(OCCCN2CCC(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1>>O=C(O)Cc1ccc(OCCCN2CCC(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 -US06838463B2,1,Clc1cc(Cl)ncn1.OC1CCCCCC1>>Clc1cc(OC2CCCCCC2)ncn1 -US04824468,2,CC(C)N=C=O.CCC1CNC(c2ccc(Cl)c(C(F)(F)F)c2)O1>>CCC1CN(C(=O)NC(C)C)C(c2ccc(Cl)c(C(F)(F)F)c2)O1 -US20110118262A1,2,Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)cc1C(=O)O.N=C(N)NC(=O)OCc1ccccc1>>Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)cc1C(=O)N(C(=N)N)C(=O)OCc1ccccc1 -US08012979B2,1,C1CCNC1.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(Cc3ccccc3)cc(C=O)c2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(Cc3ccccc3)cc(CN3CCCC3)c2c1 -US20060205718A1,1,CCOc1ccc2ccccc2c1C=O.c1ccc2sc(NC3CCNCC3)nc2c1>>CCOc1ccc2ccccc2c1CN1CCC(Nc2nc3ccccc3s2)CC1 -US07799785B2,1,CO.O=C(CBr)N1[C@@H](CNC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@@H]2c3ccccc3Cc3ccc(F)cc3[C@H]21>>COCC(=O)N1[C@@H](CNC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@@H]2c3ccccc3Cc3ccc(F)cc3[C@H]21 -US20140364413A1,1,CCOC(=O)c1cccc2nc(CBr)ccc12.CCOP(OCC)OCC>>CCOC(=O)c1cccc2nc(CP(=O)(OCC)OCC)ccc12 -US20080318923A1,1,COc1ccccc1C1(Cl)C(=O)Nc2ccc(Cl)cc21.O=C([C@@H]1CC(F)CN1)N1CCC1>>COc1ccccc1C1(N2CC(F)C[C@H]2C(=O)N2CCC2)C(=O)Nc2ccc(Cl)cc21 -US20120022044A1,1,Nc1ccncc1.O=C1C(n2cc(-c3ccc(Br)cc3)nn2)CCc2c(F)cccc2N1CC(F)(F)F>>O=C1C(n2cc(-c3ccc(Nc4ccncc4)cc3)nn2)CCc2c(F)cccc2N1CC(F)(F)F -US06414005B1,1,CC(C)(C)OC(=O)NC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(-n2cccc2)c(CBr)c1>>CC(C)(C)OC(=O)N(Cc1cc([N+](=O)[O-])ccc1-n1cccc1)C(=O)OC(C)(C)C -US08119663B2,7,NC(=O)c1cncc(-c2ccc(C(F)(F)F)cc2)c1>>NC(=O)C1CNCC(c2ccc(C(F)(F)F)cc2)C1 -US20030139418A1,1,COC(=O)c1ccc(N)cc1.O=Cc1cc(Br)ccc1CCc1ccccc1>>COC(=O)c1ccc(NCc2cc(Br)ccc2CCc2ccccc2)cc1 -US08426448B2,6,CC(=O)NC(C)(C)c1cccc(C(F)(F)F)n1>>CC(C)(N)c1cccc(C(F)(F)F)n1 -US06511974B1,1,Cc1c[nH]cn1.O=C(c1ccc(F)cc1C(F)(F)F)N1Cc2cccn2Cc2ccccc21>>Cc1cn(-c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)c(C(F)(F)F)c2)cn1 -US20140073651A1,1,COC(=O)c1cc(N)ccc1Cl.Clc1ccc(Cl)nn1>>COC(=O)c1cc(Nc2ccc(Cl)nn2)ccc1Cl -US05840751,1,CC(C)c1ccccc1S.O=C1OC(CCc2ccccc2)(c2ccccc2)CC(O)=C1Br>>CC(C)c1ccccc1SC1=C(O)CC(CCc2ccccc2)(c2ccccc2)OC1=O -US04499094,2,CCC(C)NC.O=C(O)c1cc2ccccc2c(-c2ccccc2F)n1>>CCC(C)N(C)C(=O)c1cc2ccccc2c(-c2ccccc2F)n1 -US20100311749A1,2,O=C(Cl)c1cccc(Cl)c1Cl.O=C1CNCCN1c1cc(N2CCOCC2)ccc1Cl>>O=C(c1cccc(Cl)c1Cl)N1CCN(c2cc(N3CCOCC3)ccc2Cl)C(=O)C1 -US05864039,1,ClCCCCCBr.SCc1ccccc1>>ClCCCCCSCc1ccccc1 -US20090012010A1,1,CC(C)(C)c1cc(Br)ccc1O.CI>>COc1ccc(Br)cc1C(C)(C)C -US20070072928A1,1,CC1(C)C(=O)Nc2c(F)cccc21.Fc1cccc(CBr)c1>>CC1(C)C(=O)N(Cc2cccc(F)c2)c2c(F)cccc21 -US08030317B2,1,BrCc1ccccc1.CNc1cc(=O)[nH]cn1>>CNc1cc(=O)n(Cc2ccccc2)cn1 -US20030236276A1,1,BrCc1ccccc1.c1ccc2c(c1)CCN2>>c1ccc(CN2CCc3ccccc32)cc1 -US06593355B2,2,C1CCNC1.CN(Cc1ccccc1)c1ccc(C(C)(CO)C(=O)O)cc1[N+](=O)[O-]>>CN(Cc1ccccc1)c1ccc(C(C)(CO)C(=O)N2CCCC2)cc1[N+](=O)[O-] -US08399436B2,1,FC(F)(F)c1ccc(Oc2ccccc2)cc1CBr.O=C(Nc1cc[nH]n1)c1c(F)cccc1F>>O=C(Nc1ccn(Cc2cc(Oc3ccccc3)ccc2C(F)(F)F)n1)c1c(F)cccc1F -US20090186900A1,6,CCc1cc(-c2ccc3c(c2)CC(CC(=O)NCc2cccnc2)C3=O)ccc1OC>>CCc1cc(-c2ccc3c(c2)CC(CC(=O)NCc2cccnc2)C3=O)ccc1O -US20130096102A1,1,CNc1nc(Cl)ncc1Cl.COC(=O)c1ccc(N)c(OC(F)F)c1>>CNc1nc(Nc2ccc(C(=O)OC)cc2OC(F)F)ncc1Cl -US20120172351A1,1,C1CCNC1.Cc1cc(C)nc(Cl)n1>>Cc1cc(C)nc(N2CCCC2)n1 -US20090298820A1,3,COc1ccc2[nH]cc(C=O)c2n1.O=C1COc2cc(O)cc(O)c21>>COc1ccc2[nH]cc(/C=C3\Oc4cc(O)cc(O)c4C3=O)c2n1 -US07176212B2,1,BrCCc1ccccc1.Clc1nccc(Nc2ccccc2)n1>>Clc1nccc(N(CCc2ccccc2)c2ccccc2)n1 -US05912246,1,ClCc1cn2cc(Cl)ccc2n1.Clc1ccc(N2CCNCC2)cc1>>Clc1ccc(N2CCN(Cc3cn4cc(Cl)ccc4n3)CC2)cc1 -US20140336377A1,2,CC(NC(=O)c1cc(N)ncc1Cl)c1ccc(OCC(F)(F)F)nc1.CCC(=O)Cl>>CCC(=O)Nc1cc(C(=O)NC(C)c2ccc(OCC(F)(F)F)nc2)c(Cl)cn1 -US20080275029A1,7,CC(C)(C)OC(=O)N1CCC(C=O)(c2ccc(Cl)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(c2ccc(Cl)cc2)CC1 -US20150126503A1,1,N#Cc1ccc(O)c(C(F)(F)F)c1.OC1CCOCC1>>N#Cc1ccc(OC2CCOCC2)c(C(F)(F)F)c1 -US04012513,1,CCOC(=O)CC1c2cc(OC)ccc2NC1C.Clc1nc(Cl)c2ccccc2n1>>CCOC(=O)CC1c2cc(OC)ccc2N(c2nc(Cl)nc3ccccc23)C1C -US06103736,8,O=C(OO)c1cccc(Cl)c1.c1cc2ccsc2cn1>>[O-][n+]1ccc2ccsc2c1 -US20120010247A1,1,BrC1CCCC1.CC(=O)NC(C)c1cc2ccc(CCc3ccc(O)cc3)cc2o1>>CC(=O)NC(C)c1cc2ccc(CCc3ccc(OC4CCCC4)cc3)cc2o1 -US20030139425A1,7,O=C(COc1ccc(Cl)cc1)N1CCN(Cc2ccc(F)cc2)CC1>>Fc1ccc(CN2CCN(CCOc3ccc(Cl)cc3)CC2)cc1 -US20050065140A1,1,CC(C)(C)OC(=O)N1CC(CBr)Cc2ccccc21.COc1ccc(Br)c(CC2CCNCC2)c1>>COc1ccc(Br)c(CC2CCN(CC3Cc4ccccc4N(C(=O)OC(C)(C)C)C3)CC2)c1 -US08063234B2,7,CCOC(=O)CCC(c1ccc(Cl)cc1)c1c[nH]c2c(CSC)cccc12>>CSCc1cccc2c(C(CCCO)c3ccc(Cl)cc3)c[nH]c12 -US20100240653A1,3,CCOC(=O)CS(=O)(=O)c1ccc(Br)cc1.C[C@@H]1CCCN1CCc1ccc(B(O)O)cc1>>CCOC(=O)CS(=O)(=O)c1ccc(-c2ccc(CCN3CCC[C@H]3C)cc2)cc1 -US20100210642A1,3,C#C[Si](C)(C)C.Cc1cc(-c2cc(C(F)F)n3ncc(I)c3n2)ccc1Cl>>Cc1cc(-c2cc(C(F)F)n3ncc(C#C[Si](C)(C)C)c3n2)ccc1Cl -US20020137961A1,1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CC(C)(C)[Si](C)(C)Oc1ccc([C@@H]2CC[C@@H](O)CC2)c(O[Si](C)(C)C(C)(C)C)c1>>CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O[C@@H]1CC[C@@H](c2ccc(O[Si](C)(C)C(C)(C)C)cc2O[Si](C)(C)C(C)(C)C)CC1 -US20100168418A1,1,CCOC(=O)C1(CCCn2c(=O)ccc3ccc(OC)cc32)CCNCC1.O=Cc1ccc2c(c1)OCCO2>>CCOC(=O)C1(CCCn2c(=O)ccc3ccc(OC)cc32)CCN(Cc2ccc3c(c2)OCCO3)CC1 -US20060041144A1,2,C#CCOC(C(=O)Cl)c1ccc(Cl)cc1.COc1ccc(-c2ccncc2N)cc1OC>>C#CCOC(C(=O)Nc1cnccc1-c1ccc(OC)c(OC)c1)c1ccc(Cl)cc1 -US20150183893A1,3,CC(C)(C)c1cc(-c2cccc3c2C=C(Br)C3)cc(C(C)(C)C)c1.[Mg+]C1CC1>>CC(C)(C)c1cc(-c2cccc3c2C=C(C2CC2)C3)cc(C(C)(C)C)c1 -US20060084690A1,7,COC(=O)CCc1cnoc1-c1ccc(F)c(Cl)c1>>OCCCc1cnoc1-c1ccc(F)c(Cl)c1 -US20040082611A1,7,COc1ccc2c(c1)CCN=C2>>COc1ccc2c(c1)CCNC2 -US08163728B2,2,C1[NH2+]CC12COC2.Cn1nc(OCc2c(-c3ccc(F)cc3)noc2CO)cc1C(=O)O>>Cn1nc(OCc2c(-c3ccc(F)cc3)noc2CO)cc1C(=O)N1CC2(COC2)C1 -US20140057920A1,2,CC[C@@H](C)n1cc(C(=O)O)c(=O)c(Br)c1C.CS(=O)(=O)c1ccc(CN)nc1>>CC[C@@H](C)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cn2)c(=O)c(Br)c1C -US20140112945A1,2,CC(C)(C)OC(=O)NCC(=O)O.COc1ccc(C2=NN(C3CCNCC3)C(=O)C3(CCCC3)C2)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)CNC(=O)OC(C)(C)C)CC3)C(=O)C3(CCCC3)C2)cc1OC -US05783575,2,C1COCCN1.Cn1c2ccc([N+](=O)[O-])cc2c2cc(C(=O)O)sc21>>Cn1c2ccc([N+](=O)[O-])cc2c2cc(C(=O)N3CCOCC3)sc21 -US20060030600A1,1,Cc1cc(F)ccc1-c1cc(Cl)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.OC[C@@H]1CCCN1>>Cc1cc(F)ccc1-c1cc(OC[C@@H]2CCCN2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US09102625B2,2,N#CCC(=O)O.NC(=O)c1cnc(Nc2ccc(C3CCNCC3)cc2)cc1NCc1cccc(F)c1F>>N#CCC(=O)N1CCC(c2ccc(Nc3cc(NCc4cccc(F)c4F)c(C(N)=O)cn3)cc2)CC1 -US07981918B2,1,BrCc1ccccc1.Cc1cc(O)cc(C)c1C=O>>Cc1cc(OCc2ccccc2)cc(C)c1C=O -US07410963B2,3,COc1cc2c(cc1Br)C(c1cccc(C#N)c1)=NCC(=O)N2C.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cc3c(cc2OC)N(C)C(=O)CN=C3c2cccc(C#N)c2)cc1 -US05843983,1,CCOC(=O)N1C[C@H](O)C[C@H]1CCCl.Oc1ccc(Cl)cc1CCc1ccccc1>>CCOC(=O)N1C[C@H](O)C[C@H]1CCOc1ccc(Cl)cc1CCc1ccccc1 -US03988338,1,CSc1nc(Cl)c2ccnc-2[nH]1.NC1CCCCC1>>CSc1nc(NC2CCCCC2)c2ccnc-2[nH]1 -US20120029226A1,2,CCO.COc1ccc2cc(C(C)C(=O)O)ccc2c1>>CCOC(=O)C(C)c1ccc2cc(OC)ccc2c1 -US20040147519A1,1,Brc1ncccn1.CC(C)(C)OC(=O)ONCCC1CCNCC1>>CC(C)(C)OC(=O)ONCCC1CCN(c2ncccn2)CC1 -US08003655B2,1,CCOC(=O)N=S(C)(=O)c1cccc(N)c1.COc1nc(Cl)ncc1Br>>CCOC(=O)N=S(C)(=O)c1cccc(Nc2ncc(Br)c(OC)n2)c1 -US20120059028A1,3,COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1Cl)CCCC3.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1cnn(C)c1)CCCC3 -US05028629,8,CSc1ccc(CCCc2ccccc2)cc1C=CC(=O)N(C)O.O=S([O-])OO>>CN(O)C(=O)C=Cc1cc(CCCc2ccccc2)ccc1S(C)=O -US20130005707A1,7,Cc1nn(C(=O)OC(C)(C)C)c2ccc([N+](=O)[O-])cc12>>Cc1nn(C(=O)OC(C)(C)C)c2ccc(N)cc12 -US20130053364A1,3,COC(=O)c1c(CS(=O)(=O)c2ccccc2)ccc(Br)c1OC.OB(O)c1ccsc1>>COC(=O)c1c(CS(=O)(=O)c2ccccc2)ccc(-c2ccsc2)c1OC -US06531491B1,2,NC1CC1.O=C(O)c1ccc2c(-c3nc4ccccc4[nH]3)n[nH]c2c1>>O=C(NC1CC1)c1ccc2c(-c3nc4ccccc4[nH]3)n[nH]c2c1 -US05952382,1,Fc1ccc(CBr)cc1.Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2>>Fc1ccc(COc2cc3ccc(Br)cc3cc2C23CC4CC(CC(C4)C2)C3)cc1 -US04486219,7,CC12CC(CCC1=O)C(C)(C)O2>>CC1(C)OC2(C)CC1CCC2O -US05500423,1,CN1CCNCC1.Clc1nc2cccc3c2n1CCC3>>CN1CCN(c2nc3cccc4c3n2CCC4)CC1 -US20090048259A1,6,COC(=O)C1CN(c2nnc(Cl)c3ccccc23)CCN1C(=O)OC(C)(C)C>>COC(=O)C1CN(c2nnc(Cl)c3ccccc23)CCN1 -US06051712,1,CC(C)(C)OC(=O)N1CCC(c2ccc(F)cc2)C(O)C1.O=C(c1ccccc1)c1cccc(CBr)c1>>CC(C)(C)OC(=O)N1CCC(c2ccc(F)cc2)C(OCc2cccc(C(=O)c3ccccc3)c2)C1 -US20090203676A1,1,C1CNCCN1.CS(=O)c1ccc(F)cc1>>CS(=O)c1ccc(N2CCNCC2)cc1 -US06071938,1,CC1=Cc2cc(Br)ccc2OC1(C)C.COc1ccccc1S>>COc1ccccc1Sc1ccc2c(c1)C=C(C)C(C)(C)O2 -US20020035266A1,6,COC(=O)/C(=C/C1CCCC1)c1ccc(-n2nnnc2C)c(S(C)(=O)=O)c1>>Cc1nnnn1-c1ccc(/C(=C\C2CCCC2)C(=O)O)cc1S(C)(=O)=O -US04889854,2,O=C(Cl)N1CCOCC1.O=c1c(-c2ccccc2)cc(CO)c2n1NCc1ccsc1-2>>O=C(OCc1cc(-c2ccccc2)c(=O)n2c1-c1sccc1CN2)N1CCOCC1 -US04468392,2,CN=C=O.O=C1NCCCCC1Sc1ccc(Cl)cc1>>CNC(=O)N1CCCCC(Sc2ccc(Cl)cc2)C1=O -US20100317657A1,3,CC1(C)OB(c2cncc(OC(CF)CF)c2)OC1(C)C.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(-c4cncc(OC(CF)CF)c4)cc3c21 -US05663164,6,CCOC(=O)C(=NOCc1cccnc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(O)C(=NOCc1cccnc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1 -US20070282101A1,3,Brc1ccc2[nH]nc(-c3ccc[nH]3)c2c1.OB(O)c1cccnc1>>c1cncc(-c2ccc3[nH]nc(-c4ccc[nH]4)c3c2)c1 -US20140011777A1,2,CCCC(=O)Cl.Nc1c(Cl)nc2ccccc2c1NCC1(O)CCSCC1>>CCCC(=O)Nc1c(Cl)nc2ccccc2c1NCC1(O)CCSCC1 -US20110178064A1,8,OCc1cc(Br)cnc1Cl>>O=Cc1cc(Br)cnc1Cl -US08921404B2,2,CC1CCN(C(=O)Cl)CC1.Oc1noc2cc(Cl)ccc12>>CC1CCN(C(=O)Oc2noc3cc(Cl)ccc23)CC1 -US20060142333A1,2,CN1CCCc2ccc(N)cc21.O=C(O)c1ccc(-c2ccccc2)cc1>>CN1CCCc2ccc(NC(=O)c3ccc(-c4ccccc4)cc3)cc21 -US20120035214A1,2,COC[C@H](C)COCc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2c2ccc(-c3ccccc3CCN)cc2C)cc1.O=C(Cl)OCCBr>>COC[C@H](C)COCc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2c2ccc(-c3ccccc3CCNC(=O)OCCBr)cc2C)cc1 -US20070249670A1,2,COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.Nc1cc2ccccc2cc1C(=O)O>>COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1cc2ccccc2cc1N -US06867298B2,1,CCCCCCN.OCc1ccccc1Br>>CCCCCCNc1ccccc1CO -US20150232459A1,6,COC[C@@H]1CN(Cc2ccccc2)C[C@H](CO)O1>>COC[C@@H]1CNC[C@H](CO)O1 -US07749530B2,1,Cc1ccoc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CO)c1.Nc1ccc(CCN2CCCC2)cc1>>Cc1ccoc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CNc2ccc(CCN3CCCC3)cc2)c1 -US20110118480A1,6,COCCOCCOCCOCCC(=O)OC(C)(C)C>>COCCOCCOCCOCCC(=O)O -US20080287394A1,6,CN1CCn2c(c(OCc3ccccc3)c3c(=O)n(Cc4ccc(F)cc4)nc(N)c32)C1=O>>CN1CCn2c(c(O)c3c(=O)n(Cc4ccc(F)cc4)nc(N)c32)C1=O -US20030004172A1,6,COc1ccc(CNC(=O)c2cc3c(=O)n(Cc4ccc(C(=O)OC(C)(C)C)cc4)c(=O)n(C)c3s2)cc1OC>>COc1ccc(CNC(=O)c2cc3c(=O)n(Cc4ccc(C(=O)O)cc4)c(=O)n(C)c3s2)cc1OC -US04004912,2,C#CC(=O)Cl.CN1CCC(O)N(c2nnc(C3CC3)s2)C1=O>>C#CC(=O)OC1CCN(C)C(=O)N1c1nnc(C2CC2)s1 -US20140315911A1,7,CC(C)CCNc1nc(Cl)ncc1[N+](=O)[O-]>>CC(C)CCNc1nc(Cl)ncc1N -US06034107,6,COC(=O)c1ccc(C(O)C(C)O)cn1>>CC(O)C(O)c1ccc(C(=O)O)nc1 -US20150087639A1,1,O=[N+]([O-])c1ccc(F)c(F)c1.c1cc[nH]c1>>O=[N+]([O-])c1ccc(-n2cccc2)c(F)c1 -US20110213156A1,2,CC(C)c1[nH]c(C(=O)O)c(C(C)C)c1C(C)C.COC(=O)c1ccc(N)cc1>>COC(=O)c1ccc(NC(=O)c2[nH]c(C(C)C)c(C(C)C)c2C(C)C)cc1 -US07541365B2,1,CC(C)(O)c1ccc2c(c1)C(=CCCBr)c1cccnc1CO2.COC(=O)C1(C)CNCCC1(O)c1ccc(Cl)cc1>>COC(=O)C1(C)CN(CCC=C2c3cc(C(C)(C)O)ccc3OCc3ncccc32)CCC1(O)c1ccc(Cl)cc1 -US06225478B1,2,CC1=CC[C@@H]2C(C(=O)OCc3ccccc3)=CO[C@H](O)[C@@H]12.CN=C=O>>CNC(=O)O[C@@H]1OC=C(C(=O)OCc2ccccc2)[C@H]2CC=C(C)[C@@H]21 -US20070003680A1,2,CC(C)(C(=O)O)c1ccc(Br)nc1.CC(C)CN>>CC(C)CNC(=O)C(C)(C)c1ccc(Br)nc1 -US20090318470A1,1,CC(C)(C)OC(=O)N1CCN(c2ccc3[nH]nc(S(=O)(=O)c4cccc5ccccc45)c3c2)CC1.CC(C)CI>>CC(C)Cn1nc(S(=O)(=O)c2cccc3ccccc23)c2cc(N3CCN(C(=O)OC(C)(C)C)CC3)ccc21 -US20100056497A1,3,CCCCB(O)O.COCCCOc1cc(C(=O)N(C(C)C)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)ccc1Br>>CCCCc1ccc(C(=O)N(C(C)C)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)cc1OCCCOC -US20090069340A1,1,Brc1ccc(N2CCNCC2)cc1.CCn1c(CBr)c(Cl)c(=O)n1-c1ccccc1>>CCn1c(CN2CCN(c3ccc(Br)cc3)CC2)c(Cl)c(=O)n1-c1ccccc1 -US06239126B1,2,CN[C@H](Cc1ccccc1)CN1CCC(c2cc(F)ccc2OC)CC1.O=C=NC1CCCCC1>>COc1ccc(F)cc1C1CCN(C[C@@H](Cc2ccccc2)N(C)C(=O)NC2CCCCC2)CC1 -US06562989B2,1,CCCCCCN.N#Cc1ccc(Cl)cc1>>CCCCCCNc1ccc(C#N)cc1 -US08415370B2,2,CNC.O=C(O)c1cc(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)oc1C(F)(F)F>>CN(C)C(=O)c1cc(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)oc1C(F)(F)F -US05180741,7,C=CCc1cccc2c1CCC2=O>>CCCc1cccc2c1CCC2=O -US05382598,2,Nc1ccc(S(=O)(=O)c2ccccc2)c(F)c1.O=C(O)C(O)(C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc(S(=O)(=O)c2ccccc2)c(F)c1)C(O)(C(F)(F)F)C(F)(F)F -US20070129416A1,2,COc1ccc(C2=NC(C)(c3ccc(Cl)cc3)C(C)(c3ccc(Cl)cc3)N2)c(OC(C)C)c1.O=C(Cl)Cl>>COc1ccc(C2=NC(C)(c3ccc(Cl)cc3)C(C)(c3ccc(Cl)cc3)N2C(=O)Cl)c(OC(C)C)c1 -US20150005167A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)CCC(=O)Nc1ccc(Br)cn1>>C=Cc1ccc(NC(=O)CCC(=O)OC)nc1 -US08138175B2,6,O=C(NCCCN1CCC2(CC2)[C@H](O)C1)OCc1ccccc1>>NCCCN1CCC2(CC2)[C@H](O)C1 -US06756378B2,7,CC(C)(C)OC(=O)N1[C@H](C(=O)O)CC[C@@H]1c1ccccc1>>CC(C)(C)OC(=O)N1[C@H](CO)CC[C@@H]1c1ccccc1 -US20050148631A1,3,Cc1cccc(NS(=O)(=O)c2ccc(Br)c(C(F)(F)F)c2)n1.N#Cc1ccc(B(O)O)cc1>>Cc1cccc(NS(=O)(=O)c2ccc(-c3ccc(C#N)cc3)c(C(F)(F)F)c2)n1 -US05441969,3,COCc1ccoc1[Sn](C)(C)C.Cc1ccc(-n2c(N)nc3ccccc32)cc1I>>COCc1ccoc1-c1cc(-n2c(N)nc3ccccc32)ccc1C -US20100016318A1,1,CN1CCN(c2cccc(N)c2)CC1.CNC(=O)c1ccccc1Nc1nc(Cl)ncc1C>>CNC(=O)c1ccccc1Nc1nc(Nc2cccc(N3CCN(C)CC3)c2)ncc1C -US20150152117A1,2,COc1ccc(Cl)cc1-c1nn(CCN)cc1NC(=O)c1cnn2cccnc12.O=C(Cl)C1CC1>>COc1ccc(Cl)cc1-c1nn(CCNC(=O)C2CC2)cc1NC(=O)c1cnn2cccnc12 -US20050222167A1,2,CC(N)C(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1.CCc1nc(OC)c(NC(=O)N2CCN(c3cccc(F)c3)CC2)cc1C(=O)O>>CCc1nc(OC)c(NC(=O)N2CCN(c3cccc(F)c3)CC2)cc1C(=O)NC(C)C(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1 -US20100137592A1,7,N#CCC(COCc1ccccc1)COCc1ccccc1>>NCCC(COCc1ccccc1)COCc1ccccc1 -US20130210795A1,2,CCOC(=O)c1ccnc(C(=O)OCC)c1.NC1CC1>>CCOC(=O)c1ccnc(C(=O)NC2CC2)c1 -US20110105530A1,2,CS(=O)(=O)c1cccc(C(=O)Cl)c1.Nc1cc(C(=O)NCc2ccccc2)ccn1>>CS(=O)(=O)c1cccc(C(=O)Nc2cc(C(=O)NCc3ccccc3)ccn2)c1 -US20090076004A1,3,CCOC(=O)Cc1c(C(=O)OCC)c2cc(OS(=O)(=O)C(F)(F)F)ccc2n1-c1ccc(C(C)C)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)Cc1c(C(=O)OCC)c2cc(-c3ccc(C(F)(F)F)cc3)ccc2n1-c1ccc(C(C)C)cc1 -US20140171405A1,3,CN1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.COc1cc(OC)c(Cl)c(-c2ncc3c(I)n[nH]c3n2)c1Cl>>COc1cc(OC)c(Cl)c(-c2ncc3c(-c4ccc(N5CCN(C)CC5)cc4)n[nH]c3n2)c1Cl -US05461046,2,CCS(=O)(=O)CCC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(N)cc21.CS(=O)(=O)Cl>>CCS(=O)(=O)CCC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(NS(C)(=O)=O)cc21 -US08853215B2,6,CC(C)(C)OC(=O)COc1cncc(C(=O)N2CCN(c3ccccc3C(C)(C)C)CC2)c1>>CC(C)(C)c1ccccc1N1CCN(C(=O)c2cncc(OCC(=O)O)c2)CC1 -US20060281772A1,2,CC(C)c1ccc(N)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)c1ccc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1 -US05665732,1,CC(=O)n1nc(CBr)c2ccccc21.c1ccc(CCC2CCNCC2)cc1>>CC(=O)n1nc(CN2CCC(CCc3ccccc3)CC2)c2ccccc21 -US20050176791A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1OC(N)=NC1=O>>CC1OC(NC(=O)OC(C)(C)C)=NC1=O -US07112593B2,3,Brc1cccc(N2CC=CC2)c1.[Mg+]Cc1ccccc1>>C1=CCN(c2cccc(Cc3ccccc3)c2)C1 -US06794402B2,1,NCC#Cc1ccccc1.O=C1CCC(c2ccc3[nH]c(=O)oc3c2)CC1>>O=c1[nH]c2ccc([C@@H]3CC[C@@H](NCC#Cc4ccccc4)CC3)cc2o1 -US20090076074A1,2,CCn1cc(N)cn1.COc1cc(Oc2ccnc3ccc(F)cc23)ccc1C(C)C(=O)O>>CCn1cc(NC(=O)C(C)c2ccc(Oc3ccnc4ccc(F)cc34)cc2OC)cn1 -US20040235822A1,7,O=Cc1cnc2n1CCCC2>>OCc1cnc2n1CCCC2 -US04259506,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1coc2ccccc2c1=S>>Cc1ccc(S(=O)(=O)Nc2coc3ccccc3c2=S)cc1 -US20150266822A1,3,COC(=O)c1cc(Br)cc(C(=O)OC)c1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(C#N)c1>>COC(=O)c1cc(C(=O)OC)cc(-c2ccc(C)cc2C#N)c1 -US20040186101A1,6,CC1(C)OC(=O)Nc2ccc(-c3cccc(C#C[Si](C)(C)C)c3)cc21>>C#Cc1cccc(-c2ccc3c(c2)C(C)(C)OC(=O)N3)c1 -US05055464,2,NCCc1ccccc1.O=C(O)CN1C(=O)[C@@H](NC(=O)c2cc3ccccc3[nH]2)[C@H](c2ccccc2)Sc2ccccc21>>O=C(CN1C(=O)[C@@H](NC(=O)c2cc3ccccc3[nH]2)[C@H](c2ccccc2)Sc2ccccc21)NCCc1ccccc1 -US07524860B2,2,CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)OCC)n2n1.CCNCC>>CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)N(CC)CC)n2n1 -US20100168145A1,6,COc1ccc2c(c1)CCC21CCCc2cncn21>>Oc1ccc2c(c1)CCC21CCCc2cncn21 -US06172061B2,1,CI.Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN4CCCCC4)cc2)CCS3)cc1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C[N+]4(C)CCCCC4)cc2)CCS3)cc1 -US08426420B2,6,CCCCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)OCc3ccccc3)n(-c3ccccc3)n2)CC1>>CCCCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)O)n(-c3ccccc3)n2)CC1 -US20050277655A1,1,CN(C)CCCN.COc1ccccc1-c1n[nH]c2nc(Cl)ncc12>>COc1ccccc1-c1n[nH]c2nc(NCCCN(C)C)ncc12 -US20050234101A1,7,O=C(O)c1cc2cc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)ccc2s1>>OCc1cc2cc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)ccc2s1 -US08318949B2,2,Cc1nc(N2CCN(CC(=O)NCc3ccc(F)cc3)C2=O)sc1C(=O)O.NCc1cccnc1>>Cc1nc(N2CCN(CC(=O)NCc3ccc(F)cc3)C2=O)sc1C(=O)NCc1cccnc1 -US08013186B2,6,CC(C)(C)C[C@H](NC(=O)OCc1ccccc1)C12OCC(C)(CO1)CO2>>CC(C)(C)C[C@H](N)C12OCC(C)(CO1)CO2 -US03983239,1,Cc1ccc2c(c1)C1CNCCC1N2.N#CCCCBr>>Cc1ccc2c(c1)C1CN(CCCC#N)CCC1N2 -US20110201602A1,1,CC(C)(C)OC(=O)N1CCC[C@H]1CO.O=[N+]([O-])c1cc(O)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCC[C@H]1COc1cc([N+](=O)[O-])cc(C(F)(F)F)c1 -US08921573B2,6,CC(C)(C)OC(=O)N1CC2(CC2)C[C@H]1c1nc2ccc(C#C[Si](C)(C)C)cc2[nH]1>>C#Cc1ccc2nc([C@@H]3CC4(CC4)CN3C(=O)OC(C)(C)C)[nH]c2c1 -US20140010783A1,7,CC(C)(C)C#Cc1c(Cl)cc([N+](=O)[O-])cc1Cl>>CC(C)(C)C#Cc1c(Cl)cc(N)cc1Cl -US04268514,6,COc1cccc2c1Oc1ccccc1C21CCN(Cc2ccccc2)CC1>>Oc1cccc2c1Oc1ccccc1C21CCN(Cc2ccccc2)CC1 -US20090018123A1,1,CC(=O)NC[C@H]1CN(c2cc(F)c(N3CCC(n4nnc(N5CCNCC5)n4)CC3)c(F)c2)C(=O)O1.N#CBr>>CC(=O)NC[C@H]1CN(c2cc(F)c(N3CCC(n4nnc(N5CCN(C#N)CC5)n4)CC3)c(F)c2)C(=O)O1 -US03992544,4,CC1CN(Cc2ccccc2)CC(CC(=O)c2ccc(Cl)cc2)C1=O.Nc1ccc(Cl)cc1>>CC1CN(Cc2ccccc2)Cc2cc(-c3ccc(Cl)cc3)n(-c3ccc(Cl)cc3)c21 -US20080194617A1,6,CCOC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2ccc(OCc3ccccc3)cc21>>CCOC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2ccc(O)cc21 -US06756370B1,1,CC(O)(c1ccc(F)cc1)C1CCNCC1.ClCCc1ccc(Cl)s1>>CC(O)(c1ccc(F)cc1)C1CCN(CCc2ccc(Cl)s2)CC1 -US20130211131A1,2,CCCCCCCCC(=O)Cl.O=C(O)c1ccc(O)cc1>>CCCCCCCCC(=O)Oc1ccc(C(=O)O)cc1 -US20140206681A1,1,COC(=O)[C@@H]1CC[C@@H](CO)N(C(=O)[C@@H](C)Cl)C1>>COC(=O)[C@@H]1CC[C@H]2CO[C@@H](C)C(=O)N2C1 -US20040152893A1,1,CC(=O)CCl.CC(C)(C)OC(=O)Nc1ccc(Cl)c(O)c1>>CC(=O)COc1cc(NC(=O)OC(C)(C)C)ccc1Cl -US05470851,1,O=C1c2ccccc2C(=O)N1CCBr.c1ccc2c(c1)Cn1cccc1[C@@H]1CNCCN21>>O=C1c2ccccc2C(=O)N1CCN1CCN2c3ccccc3Cn3cccc3[C@@H]2C1 -US20140010783A1,2,COC(=O)c1cccc(N=C=S)c1.Cc1cc(C)n(C(=N)N)n1>>COC(=O)c1cccc(NC(=S)NC(=N)n2nc(C)cc2C)c1 -US07192950B2,6,COc1ccc(CC2c3cc(OC)c(OC)cc3S(=O)(=O)CCN2C(=O)OC(C)(C)C)cc1OC>>COc1ccc(CC2NCCS(=O)(=O)c3cc(OC)c(OC)cc32)cc1OC -US20110112135A1,10,Cc1nc2c(C(F)(F)F)cccn2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1.O=C1CCC(=O)N1Br>>CS(=O)(=O)c1cccc(Oc2cccc(-c3c(CBr)nc4c(C(F)(F)F)cccn34)c2)c1 -US05736540,2,Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1.O=C(Cl)C(Cl)c1ccccc1>>O=C(Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1)C(Cl)c1ccccc1 -US07208493B2,6,COc1ccccc1CC(=O)Nc1ccccc1-c1cc2ccccc2[nH]1>>O=C(Cc1ccccc1O)Nc1ccccc1-c1cc2ccccc2[nH]1 -US20150025065A1,3,C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)nc2cc(Cl)c(I)nc21.OB(O)c1ccc(-c2ccc(Br)cc2)cc1>>C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)nc2cc(Cl)c(-c3ccc(-c4ccc(Br)cc4)cc3)nc21 -US20140343032A1,3,CC(C)(C)[Si](C)(C)OC1CC2CC(=O)CC1N2Cc1ccccc1.CCOP(=O)(CC#N)OCC>>CC(C)(C)[Si](C)(C)OC1CC2C/C(=C\C#N)CC1N2Cc1ccccc1 -US08993586B2,6,CC(C)(C)OC(=O)N1CCC2(CC1)Cc1cnn(C(C)(C)C)c1C(=O)N2>>CC(C)(C)n1ncc2c1C(=O)NC1(CCNCC1)C2 -US06486141B2,10,COc1ccc(-c2ccc(C)cc2)cc1P(=O)(OC)OC.O=C1CCC(=O)N1Br>>COc1ccc(-c2ccc(CBr)cc2)cc1P(=O)(OC)OC -US05191109,7,COC(=O)CCC#CCCC(=O)c1ccco1>>COC(=O)CC/C=C\CCC(=O)c1ccco1 -US20090233927A1,1,CN(C)CCN.Clc1ccc2nc(NCCOc3ccccc3)ccc2c1>>CN(C)CCNc1ccc2nc(NCCOc3ccccc3)ccc2c1 -US07999132B2,7,O=C(C/C=C/c1ccccc1)Nc1cc(CCc2ccccc2)ccc1C(=O)O>>O=C(CCCc1ccccc1)Nc1cc(CCc2ccccc2)ccc1C(=O)O -US08835462B2,6,CC(C)[Si](O[C@@H]([C@H](C)O)[C@H](COC[C@@H](NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1)Cc1ccccc1)(C(C)C)C(C)C>>CC(C)[Si](O[C@@H]([C@H](C)O)[C@H](COC[C@@H](NC(=O)OC(C)(C)C)C(=O)O)Cc1ccccc1)(C(C)C)C(C)C -US08969345B2,1,C/C(C#N)=C1/c2ccc(CBr)cc2COc2cc(F)ccc21.c1ccc2[nH]c(CC3CC3)nc2c1>>C/C(C#N)=C1/c2ccc(Cn3c(CC4CC4)nc4ccccc43)cc2COc2cc(F)ccc21 -US20130184249A1,2,C#CCOC(=O)Cl.CN[C@H]1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)C[C@@H]1c1ccc(Cl)c(Cl)c1>>C#CCOC(=O)N(C)[C@H]1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)C[C@@H]1c1ccc(Cl)c(Cl)c1 -US04321386,1,CI.COc1ccc(C(=O)Nc2ccccc2CCC2CCCCN2C)cc1>>COc1ccc(C(=O)Nc2ccccc2CCC2CCCC[N+]2(C)C)cc1 -US05635197,3,CN1C(=O)CC[C@]2(C)c3ccc(Br)cc3CC[C@@H]12.OB(O)c1ccc(Cl)cc1>>CN1C(=O)CC[C@]2(C)c3ccc(-c4ccc(Cl)cc4)cc3CC[C@@H]12 -US05888941,3,C[Mg+].O=CC=C(Cl)c1ccc(Cl)cc1>>CC(O)C=C(Cl)c1ccc(Cl)cc1 -US06140351,1,CN.O=C(Nc1ccc(Cl)cn1)c1cc(Cl)ccc1NC(=O)c1scc(CCl)c1Cl>>CNCc1csc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c1Cl -US07622471B2,6,COc1ccc(-n2nc(C(=O)N3CCN(C(=O)OC(C)(C)C)CC3)cc2-c2ccccc2)cn1>>COc1ccc(-n2nc(C(=O)N3CCNCC3)cc2-c2ccccc2)cn1 -US20110200549A1,2,CCCCCNCc1ccccn1.COC(=O)Cl>>CCCCCN(Cc1ccccn1)C(=O)OC -US20130267510A1,7,COCOc1cccc2c1C1CC1(C)C(=O)O2>>COCOc1cccc(O)c1C1CC1(C)CO -US06365603B1,1,CCNCc1cc(Br)ccc1O.N#Cc1ccc(Cl)nn1>>CCN(Cc1cc(Br)ccc1O)c1ccc(C#N)nn1 -US05859007,1,CC(C)N(C(=O)CBr)c1ccccc1.Nc1ccccc1N>>CC(C)N(C(=O)CNc1ccccc1N)c1ccccc1 -US20120208814A1,3,CC(=O)N1c2ccc(Br)cc2[C@H](N)C[C@@H]1C.CN(CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1)C(=O)OC(C)(C)C>>CC(=O)N1c2ccc(-c3cnn(CCN(C)C(=O)OC(C)(C)C)c3)cc2[C@H](N)C[C@@H]1C -US07745641B2,3,C#CCCO.CC(C)(C)OC(=O)n1c(-c2ccc(N)c3c2C(=O)NC3=O)c(I)c2ccccc21>>CC(C)(C)OC(=O)n1c(-c2ccc(N)c3c2C(=O)NC3=O)c(C#CCCO)c2ccccc21 -US04381303,1,CI.Cc1nn(C)c2c1Nc1ncccc1NC2=O>>Cc1nn(C)c2c1Nc1ncccc1N(C)C2=O -US07989458B2,1,Cc1cccc(-c2nc(Cl)cc(-c3cccnc3)n2)n1.NCCc1c[nH]c2ccccc12>>Cc1cccc(-c2nc(NCCc3c[nH]c4ccccc34)cc(-c3cccnc3)n2)n1 -US04221713,7,CC(=O)CCc1ccc(C)o1>>Cc1ccc(CCC(C)O)o1 -US20110098311A1,7,N#Cc1cc2ccc([N+](=O)[O-])cc2[nH]1>>N#Cc1cc2ccc(N)cc2[nH]1 -US07999114B2,2,NC(=O)NCc1ccc(F)cc1.O=C(Cl)N(C1CCCCC1)C1CCCCC1>>O=C(NCc1ccc(F)cc1)NC(=O)N(C1CCCCC1)C1CCCCC1 -US20130281392A1,4,Nc1cc(Cl)c(Oc2ccc(F)cc2F)cc1N.O=C(O)C(F)(F)C(F)(F)F>>Fc1ccc(Oc2cc3[nH]c(C(F)(F)C(F)(F)F)nc3cc2Cl)c(F)c1 -US20130096315A1,7,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)O>>CC(C)(C)OC(=O)N[C@H](CO)Cc1ccc(Br)cc1 -US03983128,1,CCI.CCOC(=O)c1cnc2c(cnn2CC)c1O>>CCOC(=O)c1cnc2c(cnn2CC)c1OCC -US09062055B2,1,CCOC(=O)c1cc2ccc(Cl)cc2[nH]1.OB(O)c1cccc(F)c1>>CCOC(=O)c1cc2ccc(Cl)cc2n1-c1cccc(F)c1 -US20120184542A1,6,COC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(N4CCCCC4)nc3[nH]c2=O)c1>>O=C(O)c1ccc(Cl)c(NC(=O)c2cc3cnc(N4CCCCC4)nc3[nH]c2=O)c1 -US07410976B2,6,CCOc1cc(C(=O)OC)nc2c(C3CC3)cccc12>>CCOc1cc(C(=O)O)nc2c(C3CC3)cccc12 -US20150252008A1,1,Fc1ccc(Cl)c(CBr)c1.Nc1cnc(-c2ccc(C3CCC3)c(O)c2F)cn1>>Nc1cnc(-c2ccc(C3CCC3)c(OCc3cc(F)ccc3Cl)c2F)cn1 -US20150126490A1,6,CCn1cc(-c2cnc(N)c(-c3ccc(C(=O)OC)c(F)c3)n2)cn1>>CCn1cc(-c2cnc(N)c(-c3ccc(C(=O)O)c(F)c3)n2)cn1 -US20140121198A1,2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CO)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](COS(C)(=O)=O)CC1 -US20150065507A1,1,CC(C)c1ccc(N(C(C)C(C)C)S(=O)(=O)c2ccc(F)cc2)nc1.OCC1CCOCC1>>CC(C)c1ccc(N(C(C)C(C)C)S(=O)(=O)c2ccc(OCC3CCOCC3)cc2)nc1 -US20030176390A1,6,CC(C)(C)OC(=O)N1CC[C@H](NC(=O)C(F)(F)F)C1>>O=C(N[C@H]1CCNC1)C(F)(F)F -US20140378463A1,6,CC1c2nc(-c3ccccc3)c(-c3ccccc3)nc2CCN1C(=O)OC(C)(C)C>>CC1NCCc2nc(-c3ccccc3)c(-c3ccccc3)nc21 -US20100168080A1,1,CC1(C)CNCCC1(O)Cc1ccc(Cl)cc1.O=C(CCBr)Nc1ccc(Cl)cc1[N+](=O)[O-]>>CC1(C)CN(CCC(=O)Nc2ccc(Cl)cc2[N+](=O)[O-])CCC1(O)Cc1ccc(Cl)cc1 -US06077958,7,CCOC(=O)CC(C)=O>>CCOC(=O)CC(C)O -US09126970B2,6,CC(C)(C)OC(=O)n1c2ccc(-c3ccc(N(c4ccc(-c5ccccc5)cc4)c4ccc5c(c4)C(C)(C)c4ccccc4-5)cc3)cc2c2cc3c(cc21)C(C)(C)c1ccccc1-3>>CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5[nH]c6cc7c(cc6c5c4)-c4ccccc4C7(C)C)cc3)cc21 -US20120157469A1,1,Cc1ccc(S(=O)(=O)n2c3c(c4ccc(Br)cc42)CN(C(=O)OC(C)(C)C)CC3)cc1.O=C1CN(CCc2ccccc2)CCN1>>Cc1ccc(S(=O)(=O)n2c3c(c4ccc(N5CCN(CCc6ccccc6)CC5=O)cc42)CN(C(=O)OC(C)(C)C)CC3)cc1 -US04153448,1,C#CC(C)(C)OC(C)Cl.CN(C)C(=O)Nc1ccc(O)c(Cl)c1>>C#CC(C)(C)OC(C)Oc1ccc(NC(=O)N(C)C)cc1Cl -US05442063,1,CCl.CO/N=C(/C(N)=O)c1ccccc1COc1cc(C)ccc1C>>CNC(=O)/C(=N/OC)c1ccccc1COc1cc(C)ccc1C -US05935990,4,CC(=O)CCC(=O)c1ccc(S(C)(=O)=O)cc1.NC1CCCCC1>>Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1C1CCCCC1 -US20040224952A1,3,CC1CCCN1CCc1nc2ccc(Br)cc2s1.OB(O)c1cccnc1>>CC1CCCN1CCc1nc2ccc(-c3cccnc3)cc2s1 -US20100286396A1,7,C=CCC1(CC=C)c2c(ccc(OC)c2OC)C=C2c3cc4c(cc3CCN21)OCO4>>C=CCC1(CC=C)c2c(ccc(OC)c2OC)CC2c3cc4c(cc3CCN21)OCO4 -US04256751,6,CC(CSC(=O)c1ccccc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)OC(C)(C)C>>CC(CSC(=O)c1ccccc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)O -US06291467B1,1,Fc1cccc(C=C2CCNCC2)c1.Oc1nc(-c2ccc(F)cc2)c(CCCl)s1>>Oc1nc(-c2ccc(F)cc2)c(CCN2CCC(=Cc3cccc(F)c3)CC2)s1 -US20030186978A1,4,N#Cc1ccc(Cn2c(N)nc(=O)c3c2ncn3Cc2ccc3ccccc3c2)cc1.[N-]=[N+]=[N-]>>Nc1nc(=O)c2c(ncn2Cc2ccc3ccccc3c2)n1Cc1ccc(-c2nnn[nH]2)cc1 -US20100048636A1,7,COC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)O>>COC(=O)CC[C@@H](CO)NC(=O)OC(C)(C)C -US20100035918A1,1,BrCc1cccnc1.Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)[nH]c2=O)c1>>Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)n(Cc3cccnc3)c2=O)c1 -US20080181866A1,2,O=C(Cl)OCc1ccccc1.O=C(O)[C@@H]1C[C@@H](Cc2ccccc2)CN1>>O=C(O)[C@@H]1C[C@@H](Cc2ccccc2)CN1C(=O)OCc1ccccc1 -US20120190681A1,1,CN1CCN(c2ccc(N)cc2)CC1.N#Cc1ncc(Br)cc1F>>CN1CCN(c2ccc(Nc3cc(Br)cnc3C#N)cc2)CC1 -US04394515,4,N#CCc1ccc2c(c1)Sc1ccccc1CC2=O.[N-]=[N+]=[N-]>>O=C1Cc2ccccc2Sc2cc(Cc3nnn[nH]3)ccc21 -US06818649B2,6,COc1cc(C2OCCO2)cc2c1OC(C)(C)C=C2CO>>COc1cc(C=O)cc2c1OC(C)(C)C=C2CO -US20010006969A1,1,C=CCNc1nc(Cl)nc2ccc([N+](=O)[O-])cc12.CC(C)(C)CN>>C=CCNc1nc(NCC(C)(C)C)nc2ccc([N+](=O)[O-])cc12 -US05658928,6,CC(C)(C)OC(=O)COC1CCN(C(=O)[C@@H]2C[C@@H](O)CN2C(=O)c2ccc(C(=N)N)cc2)CC1>>N=C(N)c1ccc(C(=O)N2C[C@H](O)C[C@H]2C(=O)N2CCC(OCC(=O)O)CC2)cc1 -US07618970B2,1,CC(C)[C@]1(C(=O)N2CCN(c3cccc(C(F)(F)F)n3)CC2)CC[C@@H](N)C1.COC1COCCC1=O>>COC1COCCC1N[C@@H]1CC[C@@](C(=O)N2CCN(c3cccc(C(F)(F)F)n3)CC2)(C(C)C)C1 -US06107312,1,Cc1c(Cl)cc[n+]([O-])c1C.SCc1ccco1>>Cc1c(SCc2ccco2)cc[n+]([O-])c1C -US07910740B2,4,CC(=O)C(Cl)Cc1ccc(C)c(Cl)c1.COc1cc(NC(N)=S)ccc1-n1cnc(C)c1>>COc1cc(Nc2nc(C)c(Cc3ccc(C)c(Cl)c3)s2)ccc1-n1cnc(C)c1 -US05476933,6,COc1cc(=O)c2c(C)cccc2[nH]c1=O>>Cc1cccc2[nH]c(=O)c(O)cc(=O)c12 -US08426429B2,2,COC(OC)c1cc(Oc2cccc(N)c2)ccc1[N+](=O)[O-].O=C(Cl)OCc1ccccc1>>COC(OC)c1cc(Oc2cccc(NC(=O)OCc3ccccc3)c2)ccc1[N+](=O)[O-] -US09079930B2,6,O=C(Nc1cnc(-c2ccccn2)nc1O)OCc1ccccc1>>Nc1cnc(-c2ccccn2)nc1O -US20150203511A1,10,Cc1c(F)cccc1-n1nnn(C)c1=O.O=C1CCC(=O)N1Br>>Cn1nnn(-c2cccc(F)c2CBr)c1=O -US20150152092A1,6,COC(=O)c1cc(-c2c(C(C)C)cnn2C)c(C)s1>>Cc1sc(C(=O)O)cc1-c1c(C(C)C)cnn1C -US20150099777A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.CCOc1cc(OS(=O)(=O)C(F)(F)F)c(C2CC2)cc1C(=O)OC>>CCOc1cc(-c2ccccn2)c(C2CC2)cc1C(=O)OC -US20140350019A1,2,Cc1cc(O)c(F)c(N)c1F.O=C(O)c1cc(-c2cccc(F)c2)ccc1F>>Cc1cc(O)c(F)c(NC(=O)c2cc(-c3cccc(F)c3)ccc2F)c1F -US08845926B2,3,Brc1ccc2[nH]c3ccccc3c2c1.OB(O)c1ccc2c(c1)c1ccccc1n2-c1ccccc1>>c1ccc(-n2c3ccccc3c3cc(-c4ccc5[nH]c6ccccc6c5c4)ccc32)cc1 -US20150094305A1,1,CCc1nc2c(N[C@@H]3CC[C@@H](N4CCOCC4)CC3)nc(Cl)nc2s1.Nc1cnn(C2CCOCC2)c1>>CCc1nc2c(N[C@@H]3CC[C@@H](N4CCOCC4)CC3)nc(Nc3cnn(C4CCOCC4)c3)nc2s1 -US06479554B2,3,CCOP(=O)(CC#N)OCC.COc1ccc(C(=O)c2ccc3c(c2)OCO3)cc1OC>>COc1ccc(C(=CC#N)c2ccc3c(c2)OCO3)cc1OC -US05605901,2,NC1Cc2ccc(C3=NNC(=O)CC3)cc2C1.O=C=Nc1ccccc1>>O=C1CCC(c2ccc3c(c2)CC(NC(=O)Nc2ccccc2)C3)=NN1 -US20130065882A1,6,COC(=O)c1csc2ccccc12>>O=C(O)c1csc2ccccc12 -US20070275968A1,3,CCS(=O)(=O)c1ccc(B(O)O)cc1.Cc1cccc(-c2[nH]c(C(C)C)nc2-c2cccc(Br)c2)n1>>CCS(=O)(=O)c1ccc(-c2cccc(-c3nc(C(C)C)[nH]c3-c3cccc(C)n3)c2)cc1 -US06878705B2,1,Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)oc21.O[C@@H]1CCNC1>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CC[C@@H](O)C3)oc21 -US04435405,1,CN(C)CCS.Oc1ccc(-c2cc3ccccc3nc2Cl)cc1>>CN(C)CCSc1nc2ccccc2cc1-c1ccc(O)cc1 -US04027038,2,Nc1ccc(S(=O)(=O)O)c2cccc(S(=O)(=O)O)c12.O=C(Cl)c1cccc([N+](=O)[O-])c1>>O=C(Nc1ccc(S(=O)(=O)O)c2cccc(S(=O)(=O)O)c12)c1cccc([N+](=O)[O-])c1 -US20050282812A1,2,CCC1CN(C(C#N)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc2N1.CCOC(=O)Cl>>CCOC(=O)N1c2ccccc2N(C(C#N)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC -US05034417,7,CC(=O)c1ccc(NS(C)(=O)=O)c(Nc2ccc(F)cc2F)c1>>CC(O)c1ccc(NS(C)(=O)=O)c(Nc2ccc(F)cc2F)c1 -US20100197681A1,1,CNC.O=C(Nc1nc2cc(C(F)(F)F)cc(Cl)n2n1)c1cccnc1>>CN(C)c1cc(C(F)(F)F)cc2nc(NC(=O)c3cccnc3)nn12 -US08143278B2,1,CC1(C)C(=O)Nc2ccccc2C1=O.CI>>CN1C(=O)C(C)(C)C(=O)c2ccccc21 -US05028606,3,CC(=O)Nc1ccc(C=O)cc1.CCCBr>>CCCC(O)c1ccc(NC(C)=O)cc1 -US07951956B2,6,CCOC(=O)c1oc(N2CCCC2)cc1C>>Cc1cc(N2CCCC2)oc1C(=O)O -US04631147,7,CC1(C)CCCCC(C)(C)C1=O>>CC1(C)CCCCC(C)(C)C1O -US20140315889A1,1,CC1(C)CC(=O)c2c([nH]c3c(Cl)cc(Cl)cc23)C1.CCOC(=O)CCCCCBr>>CCOC(=O)CCCCCn1c2c(c3cc(Cl)cc(Cl)c31)C(=O)CC(C)(C)C2 -US20140336377A1,2,CC(=O)Nc1cc(C(=O)O)ccn1.NCc1cnc(OCC(F)(F)F)c(Br)c1>>CC(=O)Nc1cc(C(=O)NCc2cnc(OCC(F)(F)F)c(Br)c2)ccn1 -US20110172230A1,7,COC(=O)c1cncc(NC(=O)N2CCN(C(=O)c3cccc(OCCC4CCCCC4)c3)CC2)c1>>O=C(Nc1cncc(CO)c1)N1CCN(C(=O)c2cccc(OCCC3CCCCC3)c2)CC1 -US05723499,3,COC(=O)c1ccc(I)cc1O.OB(O)c1ccc2cc(OCc3ccccc3)c(C34CC5CC(CC(C5)C3)C4)cc2c1>>COC(=O)c1ccc(-c2ccc3cc(OCc4ccccc4)c(C45CC6CC(CC(C6)C4)C5)cc3c2)cc1O -US08691821B2,3,Brc1ccnc(Br)c1.OB(O)/C=C/c1ccc(F)cc1>>Fc1ccc(/C=C/c2cc(Br)ccn2)cc1 -US07514566B2,3,Brc1ccc2cncnc2c1.CCCC[Sn](CCCC)(CCCC)c1cnc(NC(=O)OC(C)(C)C)s1>>CC(C)(C)OC(=O)Nc1ncc(-c2ccc3cncnc3c2)s1 -US06207693B1,4,COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCN(C)CC2)ccc1NC(=O)c1cccc(N)c1N.O=C(O)CS>>COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCN(C)CC2)ccc1NC(=O)c1cccc2[nH]c(CS)nc12 -US06432950B1,1,COc1ccc(CN)cc1OC.Cc1sc2nc(Cl)nc(Cl)c2c1C>>COc1ccc(CNc2nc(Cl)nc3sc(C)c(C)c23)cc1OC -US20050171131A1,1,CS(=O)(=O)c1ccc(C=O)cc1.Nc1ccc(-c2c(N)nc(N)nc2C2CCOCC2)cc1>>CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3C3CCOCC3)cc2)cc1 -US07279580B2,3,CC(C)(O)c1ccn2c(-c3ccc(F)c(Cl)c3)cnc2c1F.OB(O)c1cccc(OC(F)(F)F)c1>>CC(C)(O)c1ccn2c(-c3ccc(F)c(-c4cccc(OC(F)(F)F)c4)c3)cnc2c1F -US20100130737A1,2,COC(=O)[C@@H](N)Cc1ccc(OCc2cccc(C)c2)cc1.O=C(O)c1cn2ccc(-c3ccc(Cl)cc3)cc2n1>>COC(=O)[C@H](Cc1ccc(OCc2cccc(C)c2)cc1)NC(=O)c1cn2ccc(-c3ccc(Cl)cc3)cc2n1 -US20080255122A1,1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.CC(C)Oc1ccc(N)cc1>>CC(C)Oc1ccc(NC2=C(c3ccccc3)S(=O)(=O)N(C(C)(C)C)C2=O)cc1 -US06906090B1,1,CCCCCCCCCBr.O=C1Nc2c(cccc2-c2ccccc2)C1=O>>CCCCCCCCCN1C(=O)C(=O)c2cccc(-c3ccccc3)c21 -US20050137213A1,1,CNc1ccc(C(=O)O)cc1.Cc1nc(Cl)c2ccccc2n1>>Cc1nc(N(C)c2ccc(C(=O)O)cc2)c2ccccc2n1 -US20120232074A1,1,COc1cc2c(Cl)c([N+](=O)[O-])cnc2cc1-c1c(C)noc1C.C[C@@H](N)c1ccccc1>>COc1cc2c(N[C@H](C)c3ccccc3)c([N+](=O)[O-])cnc2cc1-c1c(C)noc1C -US03953464,1,CCC(=O)Cl.N=C1N[SH](=O)(c2ccccc2)c2ccccc21>>CCC(=O)N=C1N[SH](=O)(c2ccccc2)c2ccccc21 -US20080269210A1,3,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.Clc1nc(N2CCOCC2)c2scc(-c3ccccc3)c2n1>>Nc1ncc(-c2nc(N3CCOCC3)c3scc(-c4ccccc4)c3n2)cn1 -US04440941,2,CC(=O)Sc1c(C)cccc1C(=O)O.CC(C)(C)OC(=O)CNC1CCCC1>>CC(=O)Sc1c(C)cccc1C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1 -US05856509,3,CN(C)C=O.Clc1cc2c(cc1Cn1c(C3OCCO3)nc(Br)c1Br)OCO2>>O=Cc1c(Br)nc(C2OCCO2)n1Cc1cc2c(cc1Cl)OCO2 -US08501804B2,3,C#C[Si](C)(C)C.CCOc1ccc(Br)cn1>>C#Cc1ccc(OCC)nc1 -US20040267015A1,2,COC(=O)Cc1cc(Cl)c(Oc2ccccc2)c(Cl)c1.NO>>O=C(Cc1cc(Cl)c(Oc2ccccc2)c(Cl)c1)NO -US05410085,7,O=[N+]([O-])c1cccc2ccccc12>>Nc1cccc2ccccc12 -US20030092712A1,6,COc1ccc(CN2Cc3c(-c4ccccc4Cl)cc(NC4CCN(C(C)(C)C)CC4)cc3N(c3c(Cl)cccc3Cl)C2=O)cc1>>CC(C)(C)N1CCC(Nc2cc(-c3ccccc3Cl)c3c(c2)N(c2c(Cl)cccc2Cl)C(=O)NC3)CC1 -US20080146565A1,6,CC(C)(C)[Si](C)(C)OC1CCN(c2cccc3c2ccn3-c2ccnc(NC3CCC(NS(C)(=O)=O)CC3)n2)C1>>CS(=O)(=O)NC1CCC(Nc2nccc(-n3ccc4c(N5CCC(O)C5)cccc43)n2)CC1 -US20140206663A1,1,CC(C)(C)OC(=O)N1CCNCC1.CC1C(=O)N(COCC[Si](C)(C)C)N=C2COc3ccc(Br)cc3N21>>CC1C(=O)N(COCC[Si](C)(C)C)N=C2COc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3N21 -US08901156B2,2,NCC1(c2nc(-c3ccccc3)cs2)CCOCC1.O=C(O)c1ccc(-c2noc(C(F)(F)F)n2)s1>>O=C(NCC1(c2nc(-c3ccccc3)cs2)CCOCC1)c1ccc(-c2noc(C(F)(F)F)n2)s1 -US20140364433A1,1,Cc1ccc(-c2cnn(C)c2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.Fc1ccc(C(F)(F)F)cn1>>Cc1ccc(-c2cnn(C)c2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(C(F)(F)F)cn2)c1 -US08367708B2,2,CCOC(=O)CC(=O)Cc1ccc(OCc2ccccc2Oc2ccccc2)cc1.[NH3+]O>>O=C(CC(=O)NO)Cc1ccc(OCc2ccccc2Oc2ccccc2)cc1 -US20140113931A1,1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1cnc(C#N)c(Br)c1.Cc1cc(N)on1>>Cc1cc(Nc2cc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)cnc2C#N)on1 -US08941099B2,3,Brc1cccc(I)c1.OB(O)c1ccc2c3c(cccc13)-c1ccccc1-2>>Brc1cccc(-c2ccc3c4c(cccc24)-c2ccccc2-3)c1 -US20080070912A1,1,CC(=O)[O-].CC(Cl)C(=O)c1c(C(C)C)nn2ccccc12>>CC(=O)OC(C)C(=O)c1c(C(C)C)nn2ccccc12 -US08372840B2,2,Cn1cncc1C(=O)O.Nc1cccc(N(Cc2ccccc2)S(=O)(=O)c2ccccc2)c1>>Cn1cncc1C(=O)Nc1cccc(N(Cc2ccccc2)S(=O)(=O)c2ccccc2)c1 -US20070167499A1,2,CC(=O)OC(C)=O.COC(=O)Cc1ccc(-c2csc(N)n2)s1>>COC(=O)Cc1ccc(-c2csc(NC(C)=O)n2)s1 -US05461049,2,CC(=O)Cl.CCCCCCCCCCCCn1nnc(C(N)C(=O)Nc2c(C(C)C)cccc2C(C)C)n1>>CCCCCCCCCCCCn1nnc(C(NC(C)=O)C(=O)Nc2c(C(C)C)cccc2C(C)C)n1 -US20060004043A1,3,N#Cc1ccc2c(c1)c(Br)nn2C1CCCCO1.OB(O)c1ccc2cc(OCCC3CCCC3)ccc2c1>>N#Cc1ccc2c(c1)c(-c1ccc3cc(OCCC4CCCC4)ccc3c1)nn2C1CCCCO1 -US20040267017A1,4,NC(=S)c1cccnc1.O=C(CBr)C1CCCCC1>>c1cncc(-c2nc(C3CCCCC3)cs2)c1 -US20020173526A1,1,Fc1ccc(/C=C/c2nc(CCl)co2)c(F)c1.Oc1cccc(CCCn2ccnn2)c1>>Fc1ccc(/C=C/c2nc(COc3cccc(CCCn4ccnn4)c3)co2)c(F)c1 -US07612067B2,3,CCC(CC)c1cc(C)nn2c(-c3sc(Br)nc3C)c(C)nc12.OB(O)c1cccnc1>>CCC(CC)c1cc(C)nn2c(-c3sc(-c4cccnc4)nc3C)c(C)nc12 -US08946260B2,1,COC(OC)c1ccncc1Br.O=C1NCCc2ccc(C(F)(F)F)cc21>>COC(OC)c1ccncc1N1CCc2ccc(C(F)(F)F)cc2C1=O -US20090226398A1,3,O=S(=O)(Oc1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)nn2)c(C(F)(F)F)c1)C(F)(F)F.OB(O)c1ccncc1>>Fc1cccc(-c2nc3cnn(Cc4ccc(-c5ccc(-c6ccncc6)cc5C(F)(F)F)nn4)cc-3n2)c1F -US20120202785A1,1,C[C@H](N)c1nc2ccccc2n1-c1ccccc1.Cc1nc2c(Cl)ncnc2[nH]1>>Cc1nc2c(N[C@@H](C)c3nc4ccccc4n3-c3ccccc3)ncnc2[nH]1 -US20130267482A1,6,CCOC(OCC)[C@H](C)N(Cc1cccc2ccccc12)C(=O)[C@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21>>CCOC(OCC)[C@H](C)N(Cc1cccc2ccccc12)C(=O)[C@@H](N)CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1 -US06316467B1,1,CCCCNC(=O)CCC(=O)c1ccccc1.NNC(N)=S>>CCCCNC(=O)CCC(=NNC(N)=S)c1ccccc1 -US20150056141A1,3,CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(Br)ccc12.[N-]=[N+]=NCc1cc(N=[N+]=[N-])cc(B(O)O)c1>>CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(-c3cc(CN=[N+]=[N-])cc(N=[N+]=[N-])c3)ccc12 -US04127720,7,CCOC(=O)c1cnc2c3ccccc3ccn2c1=O>>CCOC(=O)c1cnc2n(c1=O)CCc1ccccc1-2 -US20070270421A1,7,CCN(CC)CCCNC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])cc2C)ccn1>>CCN(CC)CCCNC(=O)Nc1cc(Oc2ccc(N)cc2C)ccn1 -US08071588B2,9,Fc1cc(Br)cc(Br)c1.N#C[Cu]>>N#Cc1cc(F)cc(Br)c1 -US04851526,1,C=CCN.O=CC1CCCC1>>C=CCNCC1CCCC1 -US06057325,7,c1ccc(CN2CCc3[nH]c4ccccc4c3C2)cc1>>c1ccc(CN2CC[C@H]3Nc4ccccc4[C@@H]3C2)cc1 -US08431525B2,7,CC(=O)Nc1ncc(-c2ccc(OC(C)=O)cc2)nc1Cc1ccccc1>>CC(=O)Nc1ncc(-c2ccc(O)cc2)nc1Cc1ccccc1 -US20080200467A1,7,COC(=O)C=C1CCCCC1>>COC(=O)CC1CCCCC1 -US20070161654A1,6,Cc1onc(-c2ccccc2)c1-c1cn(-c2ccc([N+](=O)[O-])cc2)c(COCc2ccccc2)n1>>Cc1onc(-c2ccccc2)c1-c1cn(-c2ccc([N+](=O)[O-])cc2)c(CO)n1 -US08278457B2,2,CC(C)S(=O)(=O)N[C@@H]1COC[C@H]1O.CS(=O)(=O)Cl>>CC(C)S(=O)(=O)N[C@@H]1COC[C@H]1OS(C)(=O)=O -US07259177B2,6,Cc1ccc(-c2nc(CO[C@@H]3CCC[C@H](CCC(C)(C)C(=O)OC(C)(C)C)C3)c(C)o2)cc1>>Cc1ccc(-c2nc(CO[C@@H]3CCC[C@H](CCC(C)(C)C(=O)O)C3)c(C)o2)cc1 -US20120046267A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#Cc1ccc2c(Br)c[nH]c2c1>>CC1(C)OB(c2c[nH]c3cc(C#N)ccc23)OC1(C)C -US20130129677A1,2,CNc1cccc(C(F)(F)F)c1.O=C(Cl)CCl>>CN(C(=O)CCl)c1cccc(C(F)(F)F)c1 -US04207234,6,O=C(NC1CN(C(C(=O)O)c2cc(Br)c(O)c(Br)c2)C1=O)C(=NO)c1ccc(OCCC(NC(=O)C(F)(F)F)C(=O)O)cc1>>NC(CCOc1ccc(C(=NO)C(=O)NC2CN(C(C(=O)O)c3cc(Br)c(O)c(Br)c3)C2=O)cc1)C(=O)O -US06297249B1,7,COC(OC)c1ccc2cccnc2n1>>COC(OC)c1ccc2c(n1)NCCC2 -US05318966,7,COc1cccc2c1CC[C@H]1[C@@H]2CC(=O)N1CC1CCCCC1>>COc1cccc2c1CC[C@H]1[C@@H]2CCN1CC1CCCCC1 -US20150087842A1,1,CN.O=C(O)c1ccc(Cl)c([N+](=O)[O-])c1>>CNc1ccc(C(=O)O)cc1[N+](=O)[O-] -US07939536B2,2,Nc1onc(-c2ccc(F)cc2)c1-c1ccncn1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1onc(-c2ccc(F)cc2)c1-c1ccncn1 -US06756373B1,6,CCCCOc1ncc(C#C[Si](C)(C)C)cc1-c1nc2c(CC)n(CCN(C)C)nc2c(=O)[nH]1>>C#Cc1cnc(OCCCC)c(-c2nc3c(CC)n(CCN(C)C)nc3c(=O)[nH]2)c1 -US20040102436A1,1,CNC1CCc2c(OCOC)cccc21.Clc1cnc(-c2ccccc2)c(-c2ccccc2)n1>>COCOc1cccc2c1CCC2N(C)c1cnc(-c2ccccc2)c(-c2ccccc2)n1 -US04861891,2,NCc1ccccc1.O=C(O)c1cccnc1Cl>>O=C(NCc1ccccc1)c1cccnc1Cl -US20140187553A1,3,CC(C)c1ccnc(Cl)n1.COC(=O)c1ccc2c(c1)c(B1OC(C)(C)C(C)(C)O1)cn2S(=O)(=O)c1ccc(C)cc1>>COC(=O)c1ccc2c(c1)c(-c1nccc(C(C)C)n1)cn2S(=O)(=O)c1ccc(C)cc1 -US20100137313A1,2,CC(C)S(N)(=O)=O.COc1cc(Nc2ncc(-c3cnc(OC)c(C(=O)O)c3)c(-n3ccc(C(F)(F)F)n3)n2)cc(OC)c1>>COc1cc(Nc2ncc(-c3cnc(OC)c(C(=O)NS(=O)(=O)C(C)C)c3)c(-n3ccc(C(F)(F)F)n3)n2)cc(OC)c1 -US20080306108A1,1,Cc1ncc(CO)c(C=O)c1O.N#Cc1ccc(N)cc1>>Cc1ncc(CO)c(CNc2ccc(C#N)cc2)c1O -US06300344B1,1,CC(C)(C)c1cccc2c1CCC[C@@]2(N[C@H](CCCO)c1nc(-c2ccccc2)c(-c2ccccc2)o1)O[SiH](c1ccccc1)c1ccccc1>>CC(C)(C)c1cccc2c1CCC[C@]2(O[SiH](c1ccccc1)c1ccccc1)N1CCC[C@@H]1c1nc(-c2ccccc2)c(-c2ccccc2)o1 -US20070244125A1,1,CS(=O)(=O)OCC(F)(F)F.O=C(c1ccc2[nH]c(C(=O)N3CCC(F)(F)CC3)cc2c1)N1CCN(C2CCCC2)CC1>>O=C(c1ccc2c(c1)cc(C(=O)N1CCC(F)(F)CC1)n2CC(F)(F)F)N1CCN(C2CCCC2)CC1 -US08309734B2,2,CC1Cc2ccccc2N1.O=C(O)c1ccccc1Oc1cc(Cl)ccc1Cl>>CC1Cc2ccccc2N1C(=O)c1ccccc1Oc1cc(Cl)ccc1Cl -US20050085520A1,2,C[C@H](C[C@H](O)[C@@H](N)Cc1ccccc1)C(=O)NCCC(C)(C)C.O=C(O)c1cc(O)cc(N2CCCC2=O)c1>>C[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(O)cc(N2CCCC2=O)c1)C(=O)NCCC(C)(C)C -US05668136,3,CN(C)c1cccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1[N+](=O)[O-].O=CCCn1cnc(-c2ccccc2)c1>>CN(C)c1cccc(C=CCCn2cnc(-c3ccccc3)c2)c1[N+](=O)[O-] -US20080076774A1,1,Clc1ncnc2[nH]ccc12.c1ccc(N2CCNCC2)cc1>>c1ccc(N2CCN(c3ncnc4[nH]ccc34)CC2)cc1 -US20060264460A1,8,CCc1nc[nH]c1CO>>CCc1nc[nH]c1C=O -US04925859,2,CCOC(=O)c1c(C(F)(F)F)nc(-c2ccccc2)c(-c2ccccc2)c1O.Nc1nccs1>>O=C(Nc1nccs1)c1c(C(F)(F)F)nc(-c2ccccc2)c(-c2ccccc2)c1O -US09079900B2,6,Cc1cc(-c2nncn2C2CCCCO2)ccc1-c1cnc2c(n1)NC1(CC1)C(=O)N2>>Cc1cc(-c2nnc[nH]2)ccc1-c1cnc2c(n1)NC1(CC1)C(=O)N2 -US20150038460A1,6,CC(C)(C)OC(=O)N1CC(Oc2nc3ccc(Br)cc3n2-c2ccnc(N)n2)C1>>Nc1nccc(-n2c(OC3CNC3)nc3ccc(Br)cc32)n1 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3sc([N+](=O)[O-])cc23)cc1Cl.c1nc[nH]n1>>COc1ccc(CNc2nc(-n3cncn3)nc3sc([N+](=O)[O-])cc23)cc1Cl -US04826836,1,CC(=Cc1sccc1C)C1(C)OCC(CCl)O1.CC1CCCNC1>>CC(=Cc1sccc1C)C1(C)OCC(CN2CCCC(C)C2)O1 -US06703392B2,1,C=CCBr.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NCc1ccccc1)CC2>>C=CCOc1cc2c(cc1OC)CCN(CC(=O)NCc1ccccc1)C2Cc1ccc(OC)c(OC)c1 -US07425631B2,2,N#CCc1ccc2c(c1)OCCC2N.O=C(O)CC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1>>N#CCc1ccc2c(c1)OCCC2NC(=O)CC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccccc1 -US20140315928A1,1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.Clc1nccc2ccccc12>>CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nccc3ccccc23)C1 -US20150218173A1,3,Brc1c[nH]c2ncnc(Nc3ccc4[nH]ncc4c3)c12.OB(O)c1ccncc1>>c1cc(-c2c[nH]c3ncnc(Nc4ccc5[nH]ncc5c4)c23)ccn1 -US09101632B2,1,C#Cc1cc(Nc2ncnc3cnc(F)cc23)ccc1Cl.COc1ccc(CN)cc1>>C#Cc1cc(Nc2ncnc3cnc(NCc4ccc(OC)cc4)cc23)ccc1Cl -US08486967B2,1,COc1ccc(-c2ccccc2)c2nc(Cl)sc12.Cc1cc(N2CCC(N)CC2)ncn1>>COc1ccc(-c2ccccc2)c2nc(NC3CCN(c4cc(C)ncn4)CC3)sc12 -US20150080364A1,6,CC(C)(C)OC(=O)N1CCN(Cc2ccc(Cl)cc2C(=O)N2CCOCC2)CC1>>O=C(c1cc(Cl)ccc1CN1CCNCC1)N1CCOCC1 -US20120258950A1,2,CC(C)(C)n1cc(C(=O)c2cncc(N)c2)c2cnc(N)nc21.O=C(O)Cn1cc(C2CC2)cn1>>CC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C4CC4)cn3)c2)c2cnc(N)nc21 -US08846910B2,7,COc1ccc(-c2ccc(/C=C/[C@@H]3O[C@H]4OC(C)(C)O[C@H]4[C@H]3CCn3nnc4ccccc4c3=O)cc2)cc1>>COc1ccc(-c2ccc(CC[C@@H]3O[C@H]4OC(C)(C)O[C@H]4[C@H]3CCn3nnc4ccccc4c3=O)cc2)cc1 -US20080194629A1,7,COCCCCC1(CNC(=O)[C@H]2C[C@@H](NS(=O)(=O)c3ccc(CCC(=O)O)cc3)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21>>COCCCCC1(CNC(=O)[C@H]2C[C@@H](NS(=O)(=O)c3ccc(CCCO)cc3)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21 -US07199120B2,3,C#CC(C)O.Fc1cc(I)ccn1>>CC(O)C#Cc1ccnc(F)c1 -US20130203714A1,7,C[C@@H](COc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1)N1CCN(C)C(=O)C1>>C[C@@H](COc1ccc(C2CCN(C3=Nn4c(nnc4C(F)(F)F)CC3)CC2)cc1)N1CCN(C)C(=O)C1 -US20120214785A1,3,C#Cc1ccc(OCC)cc1.CC(NC(=O)OC(C)(C)C)c1ccc(Br)cc1>>CCOc1ccc(C#Cc2ccc(C(C)NC(=O)OC(C)(C)C)cc2)cc1 -US07906537B2,3,CCOC(=O)Nc1ccc(NCc2ccc(Cl)s2)cc1I.OB(O)c1cnc2ccccc2c1>>CCOC(=O)Nc1ccc(NCc2ccc(Cl)s2)cc1-c1cnc2ccccc2c1 -US05798367,2,CC(C)n1nc(C(=O)NCCN2CCC(N)CC2)c2ccccc21.O=C(Cl)c1ccccc1>>CC(C)n1nc(C(=O)NCCN2CCC(NC(=O)c3ccccc3)CC2)c2ccccc21 -US06313160B1,7,CC(=O)Oc1ccc2c(c1)OCCO2>>Oc1ccc2c(c1)OCCO2 -US20120094972A1,1,C1COCCN1.Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)ccc2c1N1CC(C)(C)c2ccc(I)cc21>>Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)ccc2c1N1CC(C)(C)c2ccc(N3CCOCC3)cc21 -US06838463B2,1,CC#CCO.Fc1ccc(F)c(Cc2cc(Cl)ncn2)c1Cl>>CC#CCOc1cc(Cc2c(F)ccc(F)c2Cl)ncn1 -US08618289B2,1,Cc1ncccc1Br.NN=C(c1ccccc1)c1ccccc1>>Cc1ncccc1NN=C(c1ccccc1)c1ccccc1 -US20150045378A1,6,COC(=O)CC(c1ccc(F)c(OCc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)n2)c1)C1CC1>>COc1ccc(F)c(-c2ccc(COc3cc(C(CC(=O)O)C4CC4)ccc3F)nc2CC(C)(C)C)c1 -US20080161340A1,3,CC(C)(C)OC(=O)N1CCc2c(cc(B(O)O)c(=O)n2CC2CCC2)C1.Fc1ccccc1CBr>>CC(C)(C)OC(=O)N1CCc2c(cc(Cc3ccccc3F)c(=O)n2CC2CCC2)C1 -US07888352B2,1,C1CC(CN2CCOCC2)CCN1.O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>Clc1nc(N2CCOCC2)c2sc(CN3CCC(CN4CCOCC4)CC3)cc2n1 -US20100331372A1,2,CCc1cc(-c2noc(-c3cc(C)c(CC(C)C)cn3)n2)cc(C)c1CCC(=O)O.CN>>CCc1cc(-c2noc(-c3cc(C)c(CC(C)C)cn3)n2)cc(C)c1CCC(=O)NC -US07220771B2,3,Brc1nn(C2CCCCO2)c2ccc(-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc12.Nc1cccc(B(O)O)c1>>Nc1cccc(-c2nn(C3CCCCO3)c3ccc(-c4nnn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1 -US20150175623A1,2,O=C(OC(=O)C(F)F)C(F)F.OCCN1CCNCC1>>O=C(C(F)F)N1CCN(CCO)CC1 -US08034812B2,2,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.Cc1cn(C)nc1C(=O)O>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1NC(=O)c1nn(C)cc1C -US07622605B2,1,C1COCCN1.CCc1nn(C)c(Cl)c1C=O>>CCc1nn(C)c(N2CCOCC2)c1C=O -US20100179139A1,2,CC(C)(C)OC(=O)N1CCC(N)CC1.O=S(=O)(Cl)c1ccc(Br)cn1>>CC(C)(C)OC(=O)N1CCC(NS(=O)(=O)c2ccc(Br)cn2)CC1 -US04279902,1,CC1(C)OCC(COCC2CCC(CO)O2)O1.CCCN(CCC)C(=O)CCl>>CCCN(CCC)C(=O)COCC1CCC(COCC2COC(C)(C)O2)O1 -US20150274673A1,6,COC(=O)C(OC(C)(C)C)c1c(C2=CCC(C)(C)CC2)c(-c2ccccc2)nn1C>>Cn1nc(-c2ccccc2)c(C2=CCC(C)(C)CC2)c1C(OC(C)(C)C)C(=O)O -US20040058913A1,7,COC(=O)c1cc2c(OC)c(OC)c(OC)cc2n1C>>COc1cc2c(cc(CO)n2C)c(OC)c1OC -US04423233,9,CCOC(=O)C(O)c1ccsc1.[NH4+]>>NC(=O)C(O)c1ccsc1 -US20040142958A1,7,N#Cc1ccc(-c2ncccc2C(F)(F)F)cc1[N+](=O)[O-]>>N#Cc1ccc(-c2ncccc2C(F)(F)F)cc1N -US20140303177A1,1,Clc1ncnc2[nH]ccc12.NC1(COCc2ccc(Cl)cc2)CCNCC1>>NC1(COCc2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 -US06881743B2,6,CC(C)(C)OC(=O)COc1ncc(C(=O)NCc2ccccc2)cc1C(=O)NCc1ccccc1>>O=C(O)COc1ncc(C(=O)NCc2ccccc2)cc1C(=O)NCc1ccccc1 -US20120035168A1,6,CCOC(=O)c1cnn(Cc2ccc(Cn3cccn3)c(OC)c2)c1>>COc1cc(Cn2cc(C(=O)O)cn2)ccc1Cn1cccn1 -US06787543B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](C)(C)O[C@@H]1C[C@H]2CNCC(C(c3ccccc3)c3ccccc3)N2C1>>CC(C)(C)OC(=O)N1CC(C(c2ccccc2)c2ccccc2)N2C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]2C1 -US20130310379A1,1,COC(=O)c1ccc(CBr)cc1.Cc1cccc(O)n1>>COC(=O)c1ccc(COc2cccc(C)n2)cc1 -US20090075983A1,7,O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCN2CCC1CC2>>Nc1ccc(OC(=O)N2CCN3CCC2CC3)cc1 -US20110086843A1,2,CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)Cl)s2)s1.CNCCNC>>CNCCN(C)S(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)s1 -US20150018343A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1ccccc1C(=O)OC)OCC>>COC(=O)c1ccccc1C=C1CCN(C(=O)OC(C)(C)C)CC1 -US20140171430A1,1,COc1ccc(C(=O)N2CC3CNCC3C2)c(OC)c1.Cc1ccnc(Cl)n1>>COc1ccc(C(=O)N2CC3CN(c4nccc(C)n4)CC3C2)c(OC)c1 -US20100130474A1,2,CC(=O)OC(C)=O.COC(=O)c1ccc(N)nc1>>COC(=O)c1ccc(NC(C)=O)nc1 -US06465507B2,3,CC(C)NS(=O)(=O)c1ccc2c(c1)CC(=O)N2.O=Cc1[nH]cc2c1CCOC2=O>>CC(C)NS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]cc3c1CCOC3=O)C(=O)N2 -US20070021443A1,1,COc1ncccc1C=O.[NH4+]>>COc1ncccc1CN -US20080287479A1,2,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(C(=O)O)c(F)cc32)CC1.CN>>CNC(=O)c1cc2[nH]c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c2cc1F -US20090062317A1,2,COc1cccc(C(=O)Cl)c1.Clc1ccc(-c2nc(NCCCN3CCNCC3)nc3ccccc23)cc1>>COc1cccc(C(=O)N2CCN(CCCNc3nc(-c4ccc(Cl)cc4)c4ccccc4n3)CC2)c1 -US20100075952A1,3,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2.O=C1Cc2c(Br)cccc2N1>>Cc1c(C=C2C(=O)Nc3cccc(Br)c32)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2 -US07569725B2,6,CCOC(=O)c1cc(Oc2ccccc2)ccc1NC(=O)c1ccc(OC)c(Cl)c1>>COc1ccc(C(=O)Nc2ccc(Oc3ccccc3)cc2C(=O)O)cc1Cl -US20120149737A1,6,COC(=O)c1cc(Cl)c(OC)c(OC(C)C)c1>>COc1c(Cl)cc(C(=O)O)cc1OC(C)C -US20090226398A1,1,Fc1cccc(-c2nc3cn[nH]cc-3n2)c1F.O=[N+]([O-])c1ccc(-c2ccc(CBr)cn2)c(C(F)(F)F)c1>>O=[N+]([O-])c1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)cn2)c(C(F)(F)F)c1 -US08530470B2,1,COC(=O)c1cc(C2CCCN2)c2oc(N3CCO[C@H](C)C3)cc(=O)c2c1.Fc1cccc(Br)c1>>COC(=O)c1cc(C2CCCN2c2cccc(F)c2)c2oc(N3CCO[C@H](C)C3)cc(=O)c2c1 -US07294624B2,1,Cc1cc(COc2ccc(C(=O)NCC3(C4CCNCC4)C(=O)NC(=O)NC3=O)cc2)c2ccccc2n1.O=Cc1cccnc1>>Cc1cc(COc2ccc(C(=O)NCC3(C4CCN(Cc5cccnc5)CC4)C(=O)NC(=O)NC3=O)cc2)c2ccccc2n1 -US20070072901A1,3,CC1(C)OB(c2cccc3c(Nc4cccc(S(N)(=O)=O)c4)nccc23)OC1(C)C.Oc1cc(Br)ccc1Cl>>NS(=O)(=O)c1cccc(Nc2nccc3c(-c4ccc(Cl)c(O)c4)cccc23)c1 -US08003649B2,2,Nc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1.O=C(Cl)CCl>>O=C(CCl)Nc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US20070244131A1,2,COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2cccc(C(=O)O)c2)n1.OCCN1CCOCC1>>COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2cccc(C(=O)OCCN3CCOCC3)c2)n1 -US20090018122A1,1,CCOCc1nc2c(N)nc3cc(O)ccc3c2n1CC(C)(C)O.Cn1ccnc1CCl>>CCOCc1nc2c(N)nc3cc(OCc4nccn4C)ccc3c2n1CC(C)(C)O -US05153214,1,COC(=O)CCCCC(Br)C(O)c1cccnc1>>COC(=O)CCCCC1OC1c1cccnc1 -US05688816,2,CN=C=O.Oc1ccc2c(ccn2Cc2ccncc2)c1>>CNC(=O)Oc1ccc2c(ccn2Cc2ccncc2)c1 -US20130296309A1,3,CC1(C)OB(c2cncc(C=O)c2)OC1(C)C.CCOc1cc(Br)ccc1C#N>>CCOc1cc(-c2cncc(C=O)c2)ccc1C#N -US06541505B1,1,CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.N#Cc1c[nH]c2ccc(CCNC(=O)c3ccc(-c4ccnc(Cl)n4)cc3)cc12>>CN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)c1nccc(-c2ccc(C(=O)NCCc3ccc4[nH]cc(C#N)c4c3)cc2)n1 -US04490366,2,CC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)C[C@@H]1OC(C)=O.Cc1ccccc1C(=O)Cl>>CC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)n(C(=O)c3ccccc3C)c2=O)C[C@@H]1OC(C)=O -US20130252890A1,1,CNCCCCS(=O)CCCC(F)(F)C(F)(F)F.Oc1ccc2c(c1F)CCCC(c1ccc(F)cc1)=C2CCCCCCBr>>CN(CCCCCCC1=C(c2ccc(F)cc2)CCCc2c1ccc(O)c2F)CCCCS(=O)CCCC(F)(F)C(F)(F)F -US20040019063A1,7,CC1(C)C=Cc2c([N+](=O)[O-])ccc(C#N)c2O1>>CC1(C)C=Cc2c(N)ccc(C#N)c2O1 -US20040110786A1,2,O=C(O)c1ccc([N+](=O)[O-])cc1.O=C1COC[C@H]([C@H](O)c2ccccc2)N1>>O=C1COC[C@H]([C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)c2ccccc2)N1 -US20080306067A1,1,CNCCCCNC(=O)Nc1cccc(-c2nnnn2C)c1.Cc1cc(C=O)ccc1F>>Cc1cc(CN(C)CCCCNC(=O)Nc2cccc(-c3nnnn3C)c2)ccc1F -US20110046169A1,8,COC(=O)c1cccc(-c2ccccc2)n1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1cccc(-c2ccccc2)[n+]1[O-] -US20020016384A1,1,C=C(C#N)CCl.COP(=O)(CCO)OC>>C=C(C#N)COCCP(=O)(OC)OC -US08877747B2,3,COc1ccc(B(O)O)cn1.O=C1C(Br)=C(c2ccc(F)cc2F)c2ccc(OCCN3CCOCC3)cc21>>COc1ccc(C2=C(c3ccc(F)cc3F)c3ccc(OCCN4CCOCC4)cc3C2=O)cn1 -US04257805,2,Nc1ccc(Br)c(Cl)c1.O=CO>>O=CNc1ccc(Br)c(Cl)c1 -US20050203064A1,1,O=S(c1ccc(C=Cc2nc(CCl)co2)cc1)C(F)(F)F.Oc1ccc(COCCn2ccnn2)cc1>>O=S(c1ccc(/C=C/c2nc(COc3ccc(COCCn4ccnn4)cc3)co2)cc1)C(F)(F)F -US20030207888A1,9,C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(Br)nc3N21.N#C[Cu]>>C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3ccc(C#N)nc3N21 -US04565816,1,Fc1ccc(C2(CCCN3CCNCC3)OCCO2)cc1.Nc1nc(Cl)ccc1[N+](=O)[O-]>>Nc1nc(N2CCN(CCCC3(c4ccc(F)cc4)OCCO3)CC2)ccc1[N+](=O)[O-] -US20140206682A1,2,Cc1ccc(C(=O)O)cc1NC(=O)c1cnc2ccccn12.NC(CO)Cc1ccccc1>>Cc1ccc(C(=O)NC(CO)Cc2ccccc2)cc1NC(=O)c1cnc2ccccn12 -US07417169B2,2,CCOC(=O)c1ccc(-c2cc(C)c(OCCO)c(C)c2)cc1.CS(=O)(=O)Cl>>CCOC(=O)c1ccc(-c2cc(C)c(OCCOS(C)(=O)=O)c(C)c2)cc1 -US08563565B2,10,Cc1cc(C)c(Br)c(C)n1.O=C1CCC(=O)N1Br>>Cc1cc(C)c(Br)c(CBr)n1 -US20110257205A1,2,CC(C)(C)OC(=O)NN.O=C(Cl)Cc1ccc(F)cc1F>>CC(C)(C)OC(=O)NNC(=O)Cc1ccc(F)cc1F -US20060247260A1,2,COC(=O)[C@@H](N)Cc1ccccc1.O=C(O)c1ccc(Cl)nc1>>COC(=O)C(Cc1ccccc1)NC(=O)c1ccc(Cl)nc1 -US08431695B2,6,Nc1ncnn2c([C@@H]3CCCN(C(=O)OCc4ccccc4)C3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>Nc1ncnn2c([C@@H]3CCCNC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12 -US20150111870A1,6,COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CO[Si](C(C)C)(C(C)C)C(C)C>>COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CO -US07629332B2,1,C1CN1.O=C(NCCCCCCO)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Cl>>O=C(NCCCCCCO)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1N1CC1 -US20080108595A1,2,C[C@H](N)CNc1ccc(OC(F)(F)F)cc1.O=C(O)[C@H](CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1>>C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1 -US05155130,1,CCCCCCBr.O=CC1=Cc2cc(O)ccc2OC1>>CCCCCCOc1ccc2c(c1)C=C(C=O)CO2 -US20090137557A1,2,CC(=O)C(C(=O)OCc1ccccc1)C1CC1.NCCc1ccccc1>>CC(=O)C(C(=O)NCCc1ccccc1)C1CC1 -US04254212,1,CCS(=O)(=O)CCO.O=C(O)c1cc(O)c2ccccc2c1O>>CCS(=O)(=O)CCOc1cc(C(=O)O)c(O)c2ccccc12 -US20150252044A1,2,NCc1ccncc1.O=C(O)c1ccc2cncc(Br)c2n1>>O=C(NCc1ccncc1)c1ccc2cncc(Br)c2n1 -US20130157851A1,7,Cc1cc([N+](=O)[O-])c(C)cc1Sc1cccc(O)c1>>Cc1cc(Sc2cccc(O)c2)c(C)cc1N -US06992087B2,1,Cc1cnc(C)c(Cl)n1.NC1CCc2ccccc21>>Cc1cnc(C)c(NC2CCc3ccccc32)n1 -US20110003787A1,6,COC[C@H](C)Oc1cc(Oc2ccc(S(=O)(=O)N(C)Cc3ccc(OC)cc3)nc2)cc(-c2ccc(C3=NC[C@H](CO)O3)[nH]2)c1>>CNS(=O)(=O)c1ccc(Oc2cc(O[C@@H](C)COC)cc(-c3ccc(C4=NC[C@H](CO)O4)[nH]3)c2)cn1 -US20130158043A1,7,CCSc1ccccc1C(=O)OC>>CCSc1ccccc1CO -US20110152240A1,3,Cc1cc(NC2CC2)n2nc(C)c(C=O)c2n1.O=C1CSC(=O)N1>>Cc1cc(NC2CC2)n2nc(C)c(C=C3SC(=O)NC3=O)c2n1 -US06673810B2,7,CCCn1c(=O)n(-c2ccc(-c3ccccc3S(C)(=O)=O)cc2)c(=O)c2c1ncn2-c1cccc(C#N)c1>>CCCn1c(=O)n(-c2ccc(-c3ccccc3S(C)(=O)=O)cc2)c(=O)c2c1ncn2-c1cccc(CN)c1 -US20100261755A1,2,COC(=O)C1CCNC(CC2CCCCC2)C1.COC(=O)Cl>>COC(=O)C1CCN(C(=O)OC)C(CC2CCCCC2)C1 -US20140171390A1,1,CCOC(=O)CC1CCC(=O)CC1.NCCNc1ccccn1>>CCOC(=O)CC1CCC(NCCNc2ccccn2)CC1 -US20120077812A1,3,CC(C)OC(=O)N1CCC(COc2ccc(Br)cc2)CC1.O=C(NC1CC1)c1ccc(B(O)O)cc1>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(C(=O)NC4CC4)cc3)cc2)CC1 -US05994378,2,CC(=O)O.CC(C)c1ccc(NN)cc1>>CC(=O)NNc1ccc(C(C)C)cc1 -US20090197868A1,6,COc1cc2c(cc1Br)C(CO)CN(C(=O)C(F)(F)F)CC2>>COc1cc2c(cc1Br)C(CO)CNCC2 -US07423044B2,1,CC(C)c1cc(O)nc(-c2cc(Cl)cc(Cl)c2)n1.Fc1ccc(CBr)cc1>>CC(C)c1cc(OCc2ccc(F)cc2)nc(-c2cc(Cl)cc(Cl)c2)n1 -US20080004273A1,7,COc1cc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2cc1OCCCN1CCOCC1>>COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCOCC1 -US09000025B2,1,CC(C)(C)[Si](C)(C)OCCn1cc(Br)cn1.CCOC(=O)c1cccc(Sc2c(C)[nH]c3c(F)c(Cl)ccc23)c1>>CCOC(=O)c1cccc(Sc2c(C)n(-c3cnn(CCO[Si](C)(C)C(C)(C)C)c3)c3c(F)c(Cl)ccc23)c1 -US20060025433A1,4,BrCCCCBr.N[C@@H]1CC[C@@H](CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2C(F)(F)F)CC1>>FC(F)(F)Oc1ccccc1CNc1ncc(C(F)(F)F)c(NC[C@@H]2CC[C@@H](N3CCCC3)CC2)n1 -US07498353B2,2,CC(C)OCNc1ccnc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1.O=C(Cl)C(Cl)Cl>>CC(C)OCN(C(=O)C(Cl)Cl)c1ccnc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1 -US20100216764A1,3,Clc1ccnc(Cl)n1.OB(O)c1cccc(C(F)(F)F)c1O>>Oc1c(-c2ccnc(Cl)n2)cccc1C(F)(F)F -US05082845,1,CC(=O)Cn1cnc2c1c(=O)[nH]c(=O)n2C.CC(O)CCCCCl>>CC(=O)Cn1cnc2c1c(=O)n(CCCCC(C)O)c(=O)n2C -US07105544B2,2,CC(C)C(=O)Nc1cccc(C2CCN(CCCN)CC2)c1.CCSC(C(=O)O)(c1ccccc1)c1ccccc1>>CCSC(C(=O)NCCCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)(c1ccccc1)c1ccccc1 -US20060148858A1,1,CC(C)c1cc[nH]n1.FC(F)(F)c1ccc(Cl)nc1>>CC(C)c1ccn(-c2ccc(C(F)(F)F)cn2)n1 -US04582837,4,COc1cc(C(=O)O)ccc1NS(C)(=O)=O.Nc1cncnc1N>>COc1cc(-c2nc3ncncc3[nH]2)ccc1NS(C)(=O)=O -US07091199B1,1,BrCCCOc1cccc(-c2noc3ccsc23)c1.Cc1ccc(CN)cc1>>Cc1ccc(CNCCCOc2cccc(-c3noc4ccsc34)c2)cc1 -US20080176862A1,3,COc1ccc(C(=O)C(=O)c2ccnc(Cl)c2)cc1.N#Cc1cccc(B(O)O)c1>>COc1ccc(C(=O)C(=O)c2ccnc(-c3cccc(C#N)c3)c2)cc1 -US05439917,7,N#CCc1c2cccn(CC(=O)c3ccccc3)c-2nc1Cl>>N#CCc1c2cccn(CC(O)c3ccccc3)c-2nc1Cl -US20100076026A1,2,Clc1ccc(-n2nc3ccccc3c2Nc2ccccc2)cc1.O=C=NC1CCCCC1>>O=C(NC1CCCCC1)N(c1ccccc1)c1c2ccccc2nn1-c1ccc(Cl)cc1 -US04963566,7,CCN1c2c(cccc2C(C)(C)C)C(=O)CC1CO[SiH](C)C>>CCN1c2c(cccc2C(C)(C)C)C(O)CC1CO[SiH](C)C -US08680339B2,1,Cc1cc(O)cc(C)c1C1C(=O)C2C3CCC(CC3)C2C1=O.Fc1cc(Cl)cnc1F>>Cc1cc(Oc2ncc(Cl)cc2F)cc(C)c1C1C(=O)C2C3CCC(CC3)C2C1=O -US20140194383A1,2,CC(C)(C)OC(=O)NCc1cccc(C2CCNCC2)c1.O=C(O)c1cccc(N2CC(O)C(O)C2)c1>>CC(C)(C)OC(=O)NCc1cccc(C2CCN(C(=O)c3cccc(N4CC(O)C(O)C4)c3)CC2)c1 -US20150079035A1,1,CCCCCCCCN.CCOC(=O)c1ccc(Cl)c([N+](=O)[O-])c1>>CCCCCCCCNc1ccc(C(=O)OCC)cc1[N+](=O)[O-] -US20140099316A1,6,CCOC(=O)C1(CO)CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(CO)CCNCC1 -US20140329797A1,2,CC(C)(c1ccc(-c2noc(-c3ccc(=O)n(Cc4cccc(C(=O)Cl)c4)n3)n2)cc1)C(F)(F)F.NCc1ccccc1>>CC(C)(c1ccc(-c2noc(-c3ccc(=O)n(Cc4cccc(C(=O)NCc5ccccc5)c4)n3)n2)cc1)C(F)(F)F -US04947881,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCC(F)(F)C(F)(F)C(F)(F)F>>Cc1ccc(S(=O)(=O)OCC(F)(F)C(F)(F)C(F)(F)F)cc1 -US04851526,7,CCN(CC)CC1CC1C(=O)c1ccc(-n2ccnc2)cc1>>CCN(CC)CC1CC1C(O)c1ccc(-n2ccnc2)cc1 -US08367681B2,3,CN1CC(=O)NC1=O.O=Cc1cnn2ccc(Nc3cccc(Cl)c3)nc12>>CN1C(=O)NC(=O)C1=Cc1cnn2ccc(Nc3cccc(Cl)c3)nc12 -US20080293940A1,2,CCO.Cc1ccc(C(=O)O)cc1I>>CCOC(=O)c1ccc(C)c(I)c1 -US20110160207A1,3,Cc1ccc(C#N)cc1Br.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(B(O)O)s1>>Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2cc(C#N)ccc2C)s1 -US20140288045A1,7,COc1cc(Cl)c(I)cc1[N+](=O)[O-]>>COc1cc(Cl)c(I)cc1N -US04806145,1,COc1cc(-n2nc(C)[nH]c2=O)ccc1C.FC(F)Cl>>COc1cc(-n2nc(C)n(C(F)F)c2=O)ccc1C -US20150018341A1,3,CC[Mg+].CON(C)C(=O)c1ccc(O)nc1>>CCC(=O)c1ccc(O)nc1 -US07652015B2,2,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(N3CCNCC3)nc2)cc1.O=C(O)c1c(F)cccc1F>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(N3CCN(C(=O)c4c(F)cccc4F)CC3)nc2)cc1 -US20130158009A1,6,Cc1cc(N[C@H]2CCN(C3CCN(C(=O)OCc4ccccc4)CC3)C2=O)c(F)cc1S(C)(=O)=O>>Cc1cc(N[C@H]2CCN(C3CCNCC3)C2=O)c(F)cc1S(C)(=O)=O -US20030166725A1,7,COc1cc(C(=O)c2cccc(C)c2)c(Oc2c(Br)cc(CC(=O)O)cc2Br)cc1C(C)C>>COc1cc(C(O)c2cccc(C)c2)c(Oc2c(Br)cc(CC(=O)O)cc2Br)cc1C(C)C -US05328922,7,Cn1ccc2cc([N+](=O)[O-])ccc21>>Cn1ccc2cc(N)ccc21 -US20090005353A1,1,CC(C)(C)N1C(=O)C(NCCCBr)=C(c2ccccc2)S1(=O)=O.CCCCNCc1ccccc1>>CCCCN(CCCNC1=C(c2ccccc2)S(=O)(=O)N(C(C)(C)C)C1=O)Cc1ccccc1 -US20080076774A1,6,COc1c(F)cccc1-c1ccc(C)c([N+](=O)[O-])c1>>Cc1ccc(-c2cccc(F)c2O)cc1[N+](=O)[O-] -US20060122065A1,2,C#CCOc1ccc(CCC(=O)Cl)cc1OC.COC(=O)c1ccc(CN)cc1>>C#CCOc1ccc(CCC(=O)NCc2ccc(C(=O)OC)cc2)cc1OC -US20140105921A1,2,CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@](C)(O)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@@](C)(O)C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCc2ccccc2)NC(=O)CN2CCOCC2)cc1 -US20030186968A1,1,C1CNCCN1.O=S(=O)(c1ccccc1)c1ccc(Cl)cn1>>O=S(=O)(c1ccccc1)c1ccc(N2CCNCC2)cn1 -US20090275538A1,2,O=C(Cl)N1CCCCC1.O=C1N=C(N2CCCCN2)S/C1=C\c1cc(F)ccc1O>>O=C1N=C(N2CCCCN2)S/C1=C/c1cc(F)ccc1OC(=O)N1CCCCC1 -US20070099909A1,7,COC(=O)c1ccc2[nH]cc(C=C[N+](=O)[O-])c2c1>>COC(=O)c1ccc2[nH]cc(CC[N+](=O)[O-])c2c1 -US20090203763A1,1,CC(O)(c1ccccc1)c1ccc(Cl)cc1.CN1CCC[C@@H]1CCCl>>CN1CCC[C@@H]1CCOC(C)(c1ccccc1)c1ccc(Cl)cc1 -US20070088044A1,1,CN1CCC(Oc2cccc3ncnc(Cl)c23)CC1.C[C@@H](N)c1ccccc1>>C[C@@H](Nc1ncnc2cccc(OC3CCN(C)CC3)c12)c1ccccc1 -US20130196974A1,1,CN(C)CCN.Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(Cl)c2c1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NCCN(C)C)c2c1 -US20040058903A1,2,Nc1ccc(CCc2ccccn2)cc1.O=C(O)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(CCc2ccccn2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1 -US20100240702A1,7,Cc1cccc2c1c(Cn1c(=O)n(C3=C(C(=O)O)CCC3)c3ccccc31)cn2C>>Cc1cccc2c1c(Cn1c(=O)n(C3CCCC3C(=O)O)c3ccccc31)cn2C -US06444679B1,4,CCCC(C)CN1CCC(c2cccc(C#N)c2)(c2ncc(C(=O)N(CC)CC)cn2)CC1.C[Si](C)(C)N=[N+]=[N-]>>CCCC(C)CN1CCC(c2cccc(-c3nnn[nH]3)c2)(c2ncc(C(=O)N(CC)CC)cn2)CC1 -US20150218096A1,1,C1COCCN1.COC(=O)c1c(Cl)cccc1Br>>COC(=O)c1c(Cl)cccc1N1CCOCC1 -US20070142504A1,3,CN(C)C=O.COCc1cc(Br)cc(COC)c1>>COCc1cc(C=O)cc(COC)c1 -US20140073620A1,1,Cn1ccc(N)n1.NC(=O)C1(c2ccccc2CCc2nc(Cl)ncc2Cl)CC1>>Cn1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)n1 -US05250548,1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CN)cc1.CCCCc1ncc(C(=O)OCC)c(Cl)n1>>CCCCc1ncc(C(=O)OCC)c(NCc2ccc(-c3ccccc3C(=O)OC(C)(C)C)cc2)n1 -US05258382,6,CCOC(=O)C1(CC(=O)OC(C)(C)C)C(=O)N(Cc2ccc(Br)cc2F)C(=O)c2cccn21>>CCOC(=O)C1(CC(=O)O)C(=O)N(Cc2ccc(Br)cc2F)C(=O)c2cccn21 -US05436259,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCCC(=O)Nc1ccc(Cl)c(-n2nc(CC)n(Cc3ccc(-c4ccccc4S(N)(=O)=O)cc3F)c2=O)c1>>CCCCC(=O)Nc1ccc(Cl)c(-n2nc(CC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)OC(C)(C)C)cc3F)c2=O)c1 -US06479531B1,2,CCOC(=O)C(N)C(=O)CCC12CC3CC(CC(C3)C1)C2.Cc1ccccc1C(=O)Cl>>CCOC(=O)C(NC(=O)c1ccccc1C)C(=O)CCC12CC3CC(CC(C3)C1)C2 -US08642637B2,9,O=C(O)c1cc(Br)c(Br)o1>>O=C(O)c1cc(Br)co1 -US05102667,2,COc1ccccc1CC(=O)O.NCc1cccs1>>COc1ccccc1CC(=O)NCc1cccs1 -US20040157894A1,1,COC(=O)c1ccc(CO)cc1.Oc1ccccc1>>COC(=O)c1ccc(COc2ccccc2)cc1 -US20070225271A1,1,CCOC(=O)N1CCC(N)CC1.Clc1ncccn1>>CCOC(=O)N1CCC(Nc2ncccn2)CC1 -US20130158075A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.NCC(=O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CCC(C(=O)NCC(=O)c2ccc([N+](=O)[O-])cc2)CC1 -US06627644B2,6,CCCN(CC1CCN(C(=O)OC(C)(C)C)CC1)C1CCc2ccc([N+](=O)[O-])cc2C1>>CCCN(CC1CCNCC1)C1CCc2ccc([N+](=O)[O-])cc2C1 -US20090005370A1,1,FC(F)(F)c1onc(-c2ccccc2)c1-c1c[nH]cn1.OB(O)c1ccccc1>>FC(F)(F)c1onc(-c2ccccc2)c1-c1cn(-c2ccccc2)cn1 -US20150225422A1,9,CC(=O)Nc1cc(-c2cnc(Cl)c(S(=O)(=O)NC(C)(C)C)c2C)ccn1>>CC(=O)Nc1cc(-c2cncc(S(=O)(=O)NC(C)(C)C)c2C)ccn1 -US06040411,1,BrCCCCBr.C=CCOc1ccc(C(=O)Oc2ccc(O)cc2)cc1>>C=CCOc1ccc(C(=O)Oc2ccc(OCCCCBr)cc2)cc1 -US20130196974A1,1,Clc1nc(OCc2ccccc2)c2cc(Br)ccc2n1.c1ccc2c(c1)CNCCS2>>Brc1ccc2nc(N3CCSc4ccccc4C3)nc(OCc3ccccc3)c2c1 -US20100075965A1,6,O=C(Nc1cn2cc(Br)ccc2n1)C(F)(F)F>>Nc1cn2cc(Br)ccc2n1 -US20110224193A1,2,Nc1ccc(Cl)nc1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>O=C(Nc1ccc(Cl)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US06927228B2,2,CNCc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1.O=C(Cl)Cc1ccccc1>>CN(Cc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1)C(=O)Cc1ccccc1 -US08415345B2,1,CC(C)CN.O=S(=O)(Nc1cccc(-c2ncsc2-c2ccnc(Cl)n2)c1)c1c(F)cccc1F>>CC(C)CNc1nccc(-c2scnc2-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2)n1 -US20100048636A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCC(CC12CCC(CC1)CC2)NC(=O)OCc1ccccc1>>CN(CC(CC12CCC(CC1)CC2)NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C -US20100261755A1,7,COC(=O)c1ccnc(-c2cc(F)c(C(F)(F)F)c(F)c2)c1>>COC(=O)C1CCNC(c2cc(F)c(C(F)(F)F)c(F)c2)C1 -US03954754,9,NN.O=C(OCc1ccccc1)N1CCc2nnc(Cl)cc2C1>>NNc1cc2c(nn1)CCN(C(=O)OCc1ccccc1)C2 -US20100081650A1,6,COC(=O)c1ccc2c(c1)NC(=O)CS2>>O=C1CSc2ccc(C(=O)O)cc2N1 -US20100240669A1,2,CC(C)(C)OC(=O)NC1(C(=O)O)CC1.N#Cc1cc(F)ccc1Nc1ccc(CN)cc1>>CC(C)(C)OC(=O)NC1(C(=O)NCc2ccc(Nc3ccc(F)cc3C#N)cc2)CC1 -US05491152,7,CCCCC(Cc1ccc(OC)c(OC)c1)C(=O)OCC>>CCCCC(CO)Cc1ccc(OC)c(OC)c1 -US20050096380A1,7,CCOC(=O)/C(F)=C(/C)c1cc2c(cc1OCC)OC(C)(C)C=C2c1ccccc1>>CCOc1cc2c(cc1/C(C)=C(/F)CO)C(c1ccccc1)=CC(C)(C)O2 -US20110015157A1,2,CC(=O)CN.C[C@@H](c1ccc(Br)cc1)N1CC[C@](CC(=O)O)(c2ccccc2)OC1=O>>CC(=O)CNC(=O)C[C@]1(c2ccccc2)CCN([C@@H](C)c2ccc(Br)cc2)C(=O)O1 -US20090088430A1,2,CC(C)(C)OC(=O)N1CCC(N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(C(=O)O)cc4)cc3Cl)C2=O)CC1.FC(F)(F)C1CCNCC1>>CC(C)(C)OC(=O)N1CCC(N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(C(=O)N5CCC(C(F)(F)F)CC5)cc4)cc3Cl)C2=O)CC1 -US07485652B2,7,Cc1oc(C=Cc2ccccc2)nc1CN1c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2CC1C>>Cc1oc(CCc2ccccc2)nc1CN1c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2CC1C -US07276516B2,7,N#CC1(c2ccccc2F)CCC1>>NCC1(c2ccccc2F)CCC1 -US07015218B1,1,C1COCCN1.N#Cc1cc([N+](=O)[O-])ccc1Cl>>N#Cc1cc([N+](=O)[O-])ccc1N1CCOCC1 -US20090247577A1,1,C=C(C)CN.CC(C)(C)OC(=O)N1C[C@@H](Cc2ccccc2)[C@H](C=O)C1>>C=C(C)CNC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1Cc1ccccc1 -US20150011508A1,2,CN.Cc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccc(-c5c(C)nn(CC(=O)O)c5C)cn34)c2)no1>>CNC(=O)Cn1nc(C)c(-c2ccc3ncc(C(=O)Nc4cc(-c5noc(C)n5)ccc4C)n3c2)c1C -US04297493,9,N.O=c1c(Cl)c(Cl)cnn1-c1ccccc1>>Nc1cnn(-c2ccccc2)c(=O)c1Cl -US04728646,1,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3c(SCc4ccc(Cl)cc4)ncnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3c(SCc4ccc(Cl)cc4)ncnc23)CC1 -US05187192,1,Brc1cccs1.Oc1ccc(F)cc1>>Fc1ccc(Oc2cccs2)cc1 -US07776867B2,4,N#CCC#N.O=C(CO)c1ccccc1>>N#Cc1c(-c2ccccc2)coc1N -US20140024664A1,6,CCCCOc1nc(N)c2nc(OC)n(CCCCC3CCCN(C(=O)OCc4ccccc4)C3)c2n1>>CCCCOc1nc(N)c2nc(OC)n(CCCCC3CCCNC3)c2n1 -US20150232462A1,3,CC1(C)OB(c2ccc3[nH]c(=O)oc3c2)OC1(C)C.Fc1ccc(-c2cccc(Br)n2)cc1>>O=c1[nH]c2ccc(-c3cccc(-c4ccc(F)cc4)n3)cc2o1 -US07842701B2,1,COc1ccc(CCl)cc1.O=c1[nH]c2ccccc2c(=O)o1>>COc1ccc(Cn2c(=O)oc(=O)c3ccccc32)cc1 -US06706751B2,1,BrCCCCCCBr.CC(C)(C)OC(=O)N1CCCc2cc(O)ccc21>>CC(C)(C)OC(=O)N1CCCc2cc(OCCCCCCBr)ccc21 -US06362336B1,2,CNCCOc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC.O=C(Cl)c1ccncc1>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN(C)C(=O)c1ccncc1 -US20140121200A1,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.COCCBr>>COCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1 -US08299267B2,7,COC(=O)c1cccnc1C>>Cc1ncccc1CO -US20140080822A1,6,CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)CCn1nccc1-2>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCn1nccc1-2 -US07928232B2,7,CC1(N)CN(Cc2ccccc2)C(=O)C12CC2>>CC1(N)CN(Cc2ccccc2)CC12CC2 -US20040229897A1,2,NCCCCn1cnc2c(N)nc3ccccc3c21.O=C(Cl)c1ccncc1>>Nc1nc2ccccc2c2c1ncn2CCCCNC(=O)c1ccncc1 -US20140378446A1,2,C=CC(=O)Cl.CNc1cccc(-n2c(=O)n(-c3ccc(C)c(OC)c3)c3c(N)ncnc32)c1>>C=CC(=O)N(C)c1cccc(-n2c(=O)n(-c3ccc(C)c(OC)c3)c3c(N)ncnc32)c1 -US04558129,1,Cc1cccc(C)c1NC(=O)CN1CCNCC1.OC(CBr)C1COc2ccccc2O1>>Cc1cccc(C)c1NC(=O)CN1CCN(CC(O)C2COc3ccccc3O2)CC1 -US08426420B2,6,CCCOC(=O)N1CCN(C(=O)OCc2ccccc2)CC1>>CCCOC(=O)N1CCNCC1 -US20120214784A1,3,CN(C)C=O.Cc1ccn(-c2c(F)cccc2F)n1>>Cc1nn(-c2c(F)cccc2F)cc1C=O -US05004741,2,COc1cccc(N=C=O)c1.NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)N2CCCC2)C1=O>>COc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(=O)N3CCCC3)C2=O)c1 -US07598236B2,1,Brc1cccnc1.CC(C)(C)OC(=O)N1CC[C@H]2CNC[C@H]21>>CC(C)(C)OC(=O)N1CC[C@H]2CN(c3cccnc3)C[C@H]21 -US20080300276A1,2,COc1ccc(C=C2CCNCC2)cc1.O=C(O)c1nc2ccc(O)cc2[nH]1>>COc1ccc(C=C2CCN(C(=O)c3nc4ccc(O)cc4[nH]3)CC2)cc1 -US20050215572A1,1,Clc1cccnc1Cl.FC(F)(F)c1ccc(Nc2ncnc3c2CCNC3)cc1>>FC(F)(F)c1ccc(Nc2ncnc3c2CCN(c2ncccc2Cl)C3)cc1 -US05602075,1,COC(=O)c1cccc(F)c1NS(=O)(=O)c1nc2c(Br)ncc(Br)n2n1.C[O-]>>COC(=O)c1cccc(F)c1NS(=O)(=O)c1nc2c(OC)ncc(Br)n2n1 -US20150174261A1,1,CCCCC/C=C\C/C=C\CCCCCCCCOS(C)(=O)=O.OCCO>>CCCCC/C=C\C/C=C\CCCCCCCCOCCO -US05834468,1,CC(C)(C)OC(=O)c1ccc(Cl)nc1.NCCc1cc(Br)ccc1OCc1ccccc1>>CC(C)(C)OC(=O)c1ccc(NCCc2cc(Br)ccc2OCc2ccccc2)nc1 -US20110092558A1,1,CC(=O)CCc1c(Cl)cc(Cl)cc1Cl.[NH4+]>>CC(N)CCc1c(Cl)cc(Cl)cc1Cl -US20130085157A1,2,CNOC.COc1ccc(CCC(=O)O)cc1OC>>COc1ccc(CCC(=O)N(C)OC)cc1OC -US07994185B2,2,CC(C)c1nc(-c2cccc(N)c2)c(-c2ccnc(Cl)n2)s1.O=S(=O)(Cl)c1ccco1>>CC(C)c1nc(-c2cccc(NS(=O)(=O)c3ccco3)c2)c(-c2ccnc(Cl)n2)s1 -US20040019063A1,3,N#Cc1ccc(N)cc1Cl.OB(O)c1ccccc1>>N#Cc1ccc(N)cc1-c1ccccc1 -US20130252941A1,6,CC(C)(C)OC(=O)N1CC(c2ccc(Nc3ncc(F)c4nn(-c5c(Cl)cccc5C#N)cc34)nc2)C1>>N#Cc1cccc(Cl)c1-n1cc2c(Nc3ccc(C4CNC4)cn3)ncc(F)c2n1 -US04551279,1,CCOC(=O)CBr.Nc1ccccc1>>CCOC(=O)CNc1ccccc1 -US20140235629A1,7,CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@H](CC(=O)OC)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@H](CCO)O[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US20120207679A1,1,CCNC.COc1ccc2nc(-c3ccc(F)nc3)sc2c1>>CCN(C)c1ccc(-c2nc3ccc(OC)cc3s2)cn1 -US20070124152A1,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCO)c1=O.CN>>CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCO)c1=O -US20070197577A1,1,CC(C)CC(N)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(C)C(N)=O.O=C(CBr)NOCc1ccccc1>>CC(C)CC(NCC(=O)NOCc1ccccc1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(C)C(N)=O -US20080269220A1,3,CCOCCSc1cc(C)c(Br)c(C)c1.O=Cc1cccc(B(O)O)c1>>CCOCCSc1cc(C)c(-c2cccc(C=O)c2)c(C)c1 -US20120258946A1,2,Nc1ccc(C2(O)CC2)c(F)c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(C2(O)CC2)c(F)c1)Oc1ccccc1 -US09067898B1,7,CCOC(=O)/C=C/c1ccc(O)c2c1CCC2>>CCOC(=O)CCc1ccc(O)c2c1CCC2 -US07622471B2,1,COC(=O)[C@@H](N)COCCCl>>COC(=O)[C@@H]1COCCN1 -US20110092505A1,6,CC(C)(C)OC(=O)N1CCN(c2cc(C(N)=O)c(-c3ccccc3)c(-c3ccnc(NC4CCCCC4)c3)n2)CC1>>NC(=O)c1cc(N2CCNCC2)nc(-c2ccnc(NC3CCCCC3)c2)c1-c1ccccc1 -US20110118283A1,2,CC(C)(C)C[C@@H]1N[C@@H](C(=O)O)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ncc(Cl)cc1F.COC(=O)c1ccc(N)c(OC)c1>>COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ncc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1 -US20080171739A1,2,CS(=O)(=O)Cl.OCCCc1ccc(-c2ccc(F)cc2)nc1>>CS(=O)(=O)OCCCc1ccc(-c2ccc(F)cc2)nc1 -US07259183B2,2,CC(C)(C)c1ccc(CNCCc2ccccc2)cc1.O=C(O)c1c(F)ccc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccccc2)C(=O)c2c(F)ccc3cc[nH]c23)cc1 -US05698573,2,NC1CCN(Cc2ccccc2)CC1.O=C=NC(=O)c1ccccc1>>O=C(NC(=O)c1ccccc1)NC1CCN(Cc2ccccc2)CC1 -US08691991B2,2,CC(C)C[C@@H](N)CO.CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN2CCCCCC2=O)c1=O>>CC(C)C[C@H](CO)NC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN2CCCCCC2=O)c1=O -US20100261710A1,6,O=C(CCCCCCNC(=O)c1cc2cccc3c2n1CCC3)NOC1CCCCO1>>O=C(CCCCCCNC(=O)c1cc2cccc3c2n1CCC3)NO -US20110183976A1,1,COc1ccc(C(=O)CBr)cc1Cl.O=C(O)Cc1ccc(OCc2ccc3ccccc3n2)cc1>>COc1ccc(C(=O)COC(=O)Cc2ccc(OCc3ccc4ccccc4n3)cc2)cc1Cl -US07666898B2,1,BrCc1ccccc1.COc1ccnc2[nH]c(C)cc12>>COc1ccnc2c1cc(C)n2Cc1ccccc1 -US05574042,6,CN(C(=O)c1ccccc1)c1cc(Cl)cc(Cl)c1>>CNc1cc(Cl)cc(Cl)c1 -US20120071457A1,1,CC(C)(C)OC(=O)NCCO.COC(=O)/C(Cc1ccc(O)cc1)=C(\C(=O)OC)C(C)C>>COC(=O)/C(Cc1ccc(OCCNC(=O)OC(C)(C)C)cc1)=C(\C(=O)OC)C(C)C -US05250574,1,Cc1ccc(CCl)cc1.Oc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1Cl>>Cc1ccc(COc2ccc(Oc3ccc(Cl)c(Cl)c3)cc2Cl)cc1 -US20090312342A1,6,CC(C)(C)OC(=O)N1CC[C@@H](NC(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)N1CC[C@@H](N)C1 -US20060252797A1,2,CCC(=O)Cl.Cc1csc(C2(Nc3cccc(Cl)c3)CCN(Cc3ccccc3)CC2)n1>>CCC(=O)N(c1cccc(Cl)c1)C1(c2nc(C)cs2)CCN(Cc2ccccc2)CC1 -US06291464B1,6,CC(=O)N1CCN(Cc2ccccc2)C[C@@H]1C>>CC(=O)N1CCNC[C@@H]1C -US20050239802A1,1,CCOC(=O)c1cccc(C2=C(c3cc(C)ccc3O)CCC2)n1.Fc1ccc(CBr)cc1>>CCOC(=O)c1cccc(C2=C(c3cc(C)ccc3OCc3ccc(F)cc3)CCC2)n1 -US06730675B2,7,COC(=O)c1cc(C)oc1C>>Cc1cc(CO)c(C)o1 -US08865744B1,1,O=C(O)[C@@H]1CCCN1.O=C1CCOCC1>>O=C(O)[C@@H]1CCCN1C1CCOCC1 -US20130217664A1,1,CCc1cc(-c2cnn(C)c2)ccc1N.Cn1cnc2cnc(Cl)cc21>>CCc1cc(-c2cnn(C)c2)ccc1Nc1cc2c(cn1)ncn2C -US20080153809A1,2,CC(C)(C)c1ccc(N)cc1.O=C(O)C1=CCN(c2ncccc2C(F)(F)F)CC1>>CC(C)(C)c1ccc(NC(=O)C2=CCN(c3ncccc3C(F)(F)F)CC2)cc1 -US04806551,7,O=C(O)CCn1cc(CCNS(=O)(=O)c2ccc(F)cc2)c2ccccc21>>O=C(O)CCN1CC(CCNS(=O)(=O)c2ccc(F)cc2)c2ccccc21 -US20110009454A1,2,CCCCCc1cccc(CN)c1.Cc1ccc(C(=O)O)c(N)n1>>CCCCCc1cccc(CNC(=O)c2ccc(C)nc2N)c1 -US04755598,2,CC(Cl)OC(=O)Cl.CCC(C)CO>>CCC(C)COC(=O)OC(C)Cl -US20080194579A1,1,O=[N+]([O-])c1ccc(Cl)c(Cl)c1.c1c[nH]cn1>>O=[N+]([O-])c1ccc(-n2ccnc2)c(Cl)c1 -US20080058339A1,1,C=O.CC(C)(C)OC(=O)N1CCC(NCc2ccc(-c3ccc(S(C)(=O)=O)cc3)nn2)CC1>>CN(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nn1)C1CCN(C(=O)OC(C)(C)C)CC1 -US20090264445A1,2,CC1(C)OC[C@@H](Cn2ccc(N)n2)O1.O=C(O)C(CC1(F)CCCC1)N1CC(Oc2c(F)cccc2F)=CC1=O>>CC1(C)OC[C@@H](Cn2ccc(NC(=O)C(CC3(F)CCCC3)N3CC(Oc4c(F)cccc4F)=CC3=O)n2)O1 -US20090227614A1,2,CC(=O)Cl.c1ccc(CN2CCC3(CCNc4ccccc43)CC2)cc1>>CC(=O)N1CCC2(CCN(Cc3ccccc3)CC2)c2ccccc21 -US04163112,2,CN=C=O.COC(COc1cc(C)cc(O)c1)OC>>CNC(=O)Oc1cc(C)cc(OCC(OC)OC)c1 -US20140249104A1,1,CC(C)(C)[S@](N)=O.O=C(CF)c1cc(Br)cnc1F>>CC(C)(C)[S@@](=O)/N=C(/CF)c1cc(Br)cnc1F -US05843942,1,COC(=O)c1ccc(N)cc1.CS(=O)(=O)c1ccc(OCc2ccccc2)c(C=O)c1>>COC(=O)c1ccc(NCc2cc(S(C)(=O)=O)ccc2OCc2ccccc2)cc1 -US20100298287A1,1,COc1ccc(N2CCCn3c2nc2c(Br)ccc(C(O)C(F)(F)F)c23)c(C)c1.C[O-]>>COc1ccc(N2CCCn3c2nc2c(OC)ccc(C(O)C(F)(F)F)c23)c(C)c1 -US03948892,3,C1COCCN1.C=O.CNC(=S)C(OC)c1ccccn1>>CNC(=S)C(CN1CCOCC1)(OC)c1ccccn1 -US07091352B2,9,Fc1ccc(-c2sc(Br)c(Br)c2-c2ccncc2)cc1>>Fc1ccc(-c2scc(Br)c2-c2ccncc2)cc1 -US20040235822A1,1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([C@H](O)c4cccc[n+]4[O-])cc2)CCN3)cc1.Cn1cc(C=O)cn1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([C@H](O)c4cccc[n+]4[O-])cc2)CCN3Cc2cnn(C)c2)cc1 -US08273740B2,1,CC(C)(C)OC(=O)Cn1c(S)nc2ccccc21.COc1ccccc1CCl>>COc1ccccc1CSc1nc2ccccc2n1CC(=O)OC(C)(C)C -US04549019,8,COC(=O)Nc1cc(OS(=O)(=O)c2ccc(C)cc2)nc(N)n1.O=C(OO)c1cccc(Cl)c1>>COC(=O)Nc1cc(OS(=O)(=O)c2ccc(C)cc2)nc(N)[n+]1[O-] -US20090221642A1,2,CC1(N2CCC(N3C(=O)Cc4cc(F)ccc43)CC2)CCNC1.COC(=O)Cl>>COC(=O)N1CCC(C)(N2CCC(N3C(=O)Cc4cc(F)ccc43)CC2)C1 -US20040077671A1,6,C[C@H]1CN(Cc2ccccc2)CCN1c1nc2cccnc2o1>>C[C@H]1CNCCN1c1nc2cccnc2o1 -US20090176774A1,2,Nc1cccc(Cl)c1.O=C(Cl)c1cccc2cc(Oc3ccncc3)ccc12>>O=C(Nc1cccc(Cl)c1)c1cccc2cc(Oc3ccncc3)ccc12 -US20140322355A1,2,CCOC(=O)C(=O)NN.CNC>>CN(C)C(=O)C(=O)NN -US20060166990A1,7,Cc1cc(F)ccc1Nc1ccc(C(=O)c2cc(OCC(O)CO)ccc2C)c([N+](=O)[O-])c1>>Cc1cc(F)ccc1Nc1ccc(C(=O)c2cc(OCC(O)CO)ccc2C)c(N)c1 -US05591752,2,Nc1nnn[nH]1.O=C(O)CCSC1c2ccccc2COc2ccc(OCc3ccc4ccccc4n3)cc21>>O=C(CCSC1c2ccccc2COc2ccc(OCc3ccc4ccccc4n3)cc21)Nc1nnn[nH]1 -US20130116430A1,3,O=[N+]([O-])c1cnc(O)c(I)c1.OB(O)C1CC1>>O=[N+]([O-])c1cnc(O)c(C2CC2)c1 -US20020193367A1,7,CN(C)c1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1-c1cccc(F)c1F>>CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1-c1cccc(F)c1F -US20130026422A1,1,CC1(C)c2ccccc2-n2c3ccc(Br)cc3c3cccc1c32.Nc1ccccc1Cl>>CC1(C)c2ccccc2-n2c3ccc(Nc4ccccc4Cl)cc3c3cccc1c32 -US20040133011A1,3,COC(=O)C12CCC(C=O)(CC1)CC2.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=CC12CCC(C(=O)OC)(CC1)CC2 -US20130172390A1,2,CC(=O)OC(C)=O.NC1CCc2cc(/C=C/C(=O)NC(c3cccc(C(F)(F)F)c3)C(F)(F)F)ccc21>>CC(=O)NC1CCc2cc(/C=C/C(=O)NC(c3cccc(C(F)(F)F)c3)C(F)(F)F)ccc21 -US06593326B1,1,Clc1ncc(Cl)c(Nc2ccc(Br)cc2)n1.FC(F)(F)CCCBr>>FC(F)(F)CCCN(c1ccc(Br)cc1)c1nc(Cl)ncc1Cl -US20070293567A1,1,COC(=O)C(CC(C)C)c1cc(O)cc(-c2ccc(C(F)(F)F)cc2)c1.OB(O)c1cc(F)cc(F)c1>>COC(=O)C(CC(C)C)c1cc(Oc2cc(F)cc(F)c2)cc(-c2ccc(C(F)(F)F)cc2)c1 -US20150126490A1,3,CC1(C)OB(c2ccc(C(=O)NCc3ccccc3)c(F)c2)OC1(C)C.CS(=O)(=O)CCc1cnc(N)c(Br)n1>>CS(=O)(=O)CCc1cnc(N)c(-c2ccc(C(=O)NCc3ccccc3)c(F)c2)n1 -US20150119362A1,3,CCc1cc(Cl)nc(-c2cccc(Cl)c2)n1.COC(=O)Cc1ccc(CB2OC(C)(C)C(C)(C)O2)cc1>>CCc1cc(Cc2ccc(CC(=O)OC)cc2)nc(-c2cccc(Cl)c2)n1 -US20070032508A1,6,CC(C)(C)OC(=O)N1CC(Oc2ccc3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c3c2)C1>>Clc1cc(Nc2ncnc3ccc(OC4CNC4)cc23)ccc1OCc1ccccn1 -US20130178600A1,9,CC(C)(CO)CCl.[N-]=[N+]=[N-]>>CC(C)(CO)CN=[N+]=[N-] -US08003649B2,1,CC(C)(C)OC(=O)Nc1ccc(C=O)cc1.FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12>>CC(C)(C)OC(=O)Nc1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US20130331374A1,7,N#Cc1cc([N+](=O)[O-])ccc1N1CCN(C2COC2)CC1>>N#Cc1cc(N)ccc1N1CCN(C2COC2)CC1 -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3sc(C)cc23)cc1Cl.Cc1ncc[nH]1>>COc1ccc(CNc2nc(-n3ccnc3C)nc3sc(C)cc23)cc1Cl -US04588715,8,Cc1ccc(C)c([Si](C)(C)c2ccccc2)c1CO>>Cc1ccc(C)c([Si](C)(C)c2ccccc2)c1C=O -US20120157448A1,1,CN(C)C=O.C[C@@]12CCOCC1C1(COC(N)=N1)c1cc(O)ccc1C2>>CN(C)/C=N/C1=NC2(CO1)c1cc(O)ccc1C[C@]1(C)CCOCC21 -US03959260,1,C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C(=O)CBr)CC[C@@H]12.N#C[S-]>>C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C(=O)CSC#N)CC[C@@H]12 -US20100004238A1,7,O=[N+]([O-])c1ccc(Oc2cccc3[nH]ccc23)c(Cl)c1>>Nc1ccc(Oc2cccc3[nH]ccc23)c(Cl)c1 -US20070082912A1,4,CC(=O)CCC(=O)c1cc(C)ccc1OCc1ccc(F)cc1.COC(=O)c1cc(N)cc(N2CCCC2=O)c1>>COC(=O)c1cc(N2CCCC2=O)cc(-n2c(C)ccc2-c2cc(C)ccc2OCc2ccc(F)cc2)c1 -US04954518,1,Brc1ccccc1.CS(=O)(=O)Nc1cc2occ(N)c(=O)c2cc1Oc1ccccc1>>CS(=O)(=O)Nc1cc2occ(Nc3ccccc3)c(=O)c2cc1Oc1ccccc1 -US04070373,7,N#CCC1(O)C2=C(C=CCS2)Oc2ccccc21>>NCCC1(O)C2=C(C=CCS2)Oc2ccccc21 -US08293734B2,1,BrCC1CO1.Oc1ccc(I)cc1>>Ic1ccc(OCC2CO2)cc1 -US04839379,7,CCCCCCCN1C(=O)C2CC2(c2ccc([N+](=O)[O-])cc2)C1=O>>CCCCCCCN1C(=O)C2CC2(c2ccc(N)cc2)C1=O -US05677326,6,COc1cccc(C2CNc3ccccc32)c1>>Oc1cccc(C2CNc3ccccc32)c1 -US20070060573A1,3,CCOc1ccc(Br)cc1C(=O)N[C@@H](CO)Cc1c[nH]c2ccccc12.OB(O)c1ccccc1>>CCOc1ccc(-c2ccccc2)cc1C(=O)N[C@@H](CO)Cc1c[nH]c2ccccc12 -US20080214545A1,1,CC(C)(C)[Si](C)(C)OCCC=O.CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccncc3)cc2)n(-c2cccc(N)c2)n1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccncc3)cc2)n(-c2cccc(NCCCO[Si](C)(C)C(C)(C)C)c2)n1 -US20080188528A1,2,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.Cc1cc(Cc2ccccc2)c(=O)n(CC(=O)O)c1>>Cc1cc(Cc2ccccc2)c(=O)n(CC(=O)N[C@@H](CCCNC(=N)NS(=O)(=O)c2c(C)c(C)c3c(c2C)CCC(C)(C)O3)C(=O)OC(C)(C)C)c1 -US20030114668A1,1,C[C@H]1CNC[C@@H](C)O1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(CC#CCCl)C[C@H]1Cc1ccc2ccccc2c1>>C[C@H]1CN(CC#CCN2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3ccc4ccccc4c3)C2)C[C@@H](C)O1 -US07560558B2,1,COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1O.ClCCBr>>COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1OCCCl -US04783459,1,Cc1cc(C)nc(Nc2ccccc2)n1.N#CBr>>Cc1cc(C)nc(N(C#N)c2ccccc2)n1 -US06958358B2,6,COC(=O)Cc1cccc(-c2ccccc2)c1>>O=C(O)Cc1cccc(-c2ccccc2)c1 -US07939536B2,6,COCOc1ccccc1CC(=O)Nc1onc(-c2ccc(F)cc2)c1-c1ccncn1>>O=C(Cc1ccccc1O)Nc1onc(-c2ccc(F)cc2)c1-c1ccncn1 -US20140107109A1,9,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N=[N+]=[N-])ccc2F)[C@@H](F)S(=O)(=O)C1(C)C>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)[C@@H](F)S(=O)(=O)C1(C)C -US20110082164A1,1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4N)cc3)cc2)CC1.Fc1cccc(Cc2cccc(Br)n2)c1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cccc(Cc5cccc(F)c5)n4)cc3)cc2)CC1 -US20150255720A1,3,COC(=O)c1ccc2ccccc2c1Br.OB(O)c1ccccc1>>COC(=O)c1ccc2ccccc2c1-c1ccccc1 -US05420280,7,O=CC1(Nc2ccccc2)CCN(Cc2ccccc2)CC1>>OCC1(Nc2ccccc2)CCN(Cc2ccccc2)CC1 -US08765730B2,9,Cc1cc(C(=O)C[C@H](c2ccc(C3=CCN(S(C)(=O)=O)CC3)cc2)c2ccccc2C)ccn1.NO>>Cc1cc(/C(C[C@H](c2ccc(C3=CCN(S(C)(=O)=O)CC3)cc2)c2ccccc2C)=N/O)ccn1 -US04517010,1,CC(C)OP(OC(C)C)OC(C)C.O=C(Cl)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]>>CC(C)OP(=O)(OC(C)C)C(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-] -US04325953,1,CCI.O=[N+]([O-])c1ccc(OC2(c3ccccc3)CCNCC2)cc1>>CCN1CCC(Oc2ccc([N+](=O)[O-])cc2)(c2ccccc2)CC1 -US08163906B2,3,CON(C)C(=O)c1ccc(C)nc1Cl.C[Mg+]>>CC(=O)c1ccc(C)nc1Cl -US20090221639A1,1,C[S-].N#Cc1ccc(F)c(F)c1>>CSc1ccc(C#N)cc1F -US08445489B2,1,CN1CCN(CCCO)CC1.O=c1[nH]c2ccc(Cn3nc(-c4cc(F)c(F)c(F)c4)ccc3=O)cc2[nH]1>>CN1CCN(CCCOc2c(F)cc(-c3ccc(=O)n(Cc4ccc5[nH]c(=O)[nH]c5c4)n3)cc2F)CC1 -US07678909B1,2,Cn1c(=O)c(N)c(N)c2ccccc21.O=C(NC1CCCC(C(=O)O)C1)OCc1ccccc1>>Cn1c(=O)c(NC(=O)C2CCCC(NC(=O)OCc3ccccc3)C2)c(N)c2ccccc21 -US07977362B2,1,BrCc1ccc(-c2ncco2)cc1.O=S(=O)(N[C@@H]1CCCCC[C@@H]1CO)c1ccc(Cl)cc1>>O=S(=O)(c1ccc(Cl)cc1)N(Cc1ccc(-c2ncco2)cc1)[C@@H]1CCCCC[C@@H]1CO -US20140148443A1,2,CCOc1cc(Cl)c(S(=O)(=O)NC(C)(C)C)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.OC1CCCNC1>>CCOc1cc(Cl)c(S(=O)(=O)NC(C)(C)C)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCCC(O)C1 -US05308857,2,CN=C=O.NCc1ccco1>>CNC(=O)NCc1ccco1 -US20120232056A1,6,COC(=O)c1ccc2nc(-c3cc4ccc(F)cc4o3)c(N3CCCCCC3)nc2c1>>O=C(O)c1ccc2nc(-c3cc4ccc(F)cc4o3)c(N3CCCCCC3)nc2c1 -US20030144326A1,2,CS(=O)(=O)Cl.O=[N+]([O-])c1ccc(N2CC(O)C2)cc1>>CS(=O)(=O)OC1CN(c2ccc([N+](=O)[O-])cc2)C1 -US06586617B1,2,CNc1ncc(Cl)cc1[N+](=O)[O-].Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)N(C)c2ncc(Cl)cc2[N+](=O)[O-])cc1 -US20150141409A1,2,CC(O)CN(C)C.O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1>>CC(CN(C)C)OC(=O)C(Cc1cc(=O)[nH]c2ccccc12)NC(=O)c1ccc(Cl)cc1 -US20120289500A1,2,Nn1nc(N2CCOCC2)c2ccccc2c1=O.O=C(O)Cc1ccc2ccccc2c1>>O=C(Cc1ccc2ccccc2c1)Nn1nc(N2CCOCC2)c2ccccc2c1=O -US07572801B2,2,N=C(N)COCCc1ccc(Cl)cc1.O=C(O)c1cc(Cl)cnc1Cl>>N=C(COCCc1ccc(Cl)cc1)NC(=O)c1cc(Cl)cnc1Cl -US20030229079A1,1,CC(=O)c1ccc(Cl)s1.OCc1ccc(F)cc1>>CC(=O)c1ccc(OCc2ccc(F)cc2)s1 -US04322439,2,CNc1ccccc1CCCC(=O)O.O=C(Cl)c1ccccc1>>CN(C(=O)c1ccccc1)c1ccccc1CCCC(=O)O -US07741341B2,1,CC(C)N1CCC(NC(=O)c2nc3c(CO)cccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1.COCCBr>>COCCOCc1cccc2c1nc(C(=O)NC1CCN(C(C)C)CC1)n2CC(=O)Nc1ccc(Cl)cn1 -US20110288067A1,2,C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3ccc(C(=O)O)s3)nc12)C(C)(C)C.NC1CCOCC1>>C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3ccc(C(=O)NC4CCOCC4)s3)nc12)C(C)(C)C -US20020026052A1,3,CC1(C)OB(c2csc(CN3CCOCC3)c2)OC1(C)C.Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(Br)ccc23)cc1Cl>>Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(-c4csc(CN5CCOCC5)c4)ccc23)cc1Cl -US07098332B2,1,COC(=O)C(Cc1cnc(Cl)nc1Cl)c1ccc(OC)cc1.Nc1ccccc1>>COC(=O)C(Cc1cnc(Nc2ccccc2)nc1Cl)c1ccc(OC)cc1 -US20130165446A1,7,CCCc1nc(CSc2ccc([N+](=O)[O-])c(NC)n2)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCc1nc(CSc2ccc(N)c(NC)n2)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1 -US06329381B1,6,COc1nc2c(N)nc(OCCCCO)nc2n1Cc1ccccc1>>Nc1nc(OCCCCO)nc2c1nc(O)n2Cc1ccccc1 -US04891375,1,FC(F)(F)c1cccc(N2CCNCC2)c1.Nc1nc(-c2ccc(CCCl)cc2)cs1>>Nc1nc(-c2ccc(CCN3CCN(c4cccc(C(F)(F)F)c4)CC3)cc2)cs1 -US20080167320A1,8,Fc1ccc(-c2ccncc2)cc1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc(-c2ccc(F)cc2)cc1 -US20080242655A1,1,CCOC(=O)c1[nH]c2c(Cl)cncc2c1N.C[Si](C)(C)c1ccc(OS(=O)(=O)C(F)(F)F)c(F)c1>>CCOC(=O)c1[nH]c2c(Cl)cncc2c1Nc1ccc([Si](C)(C)C)cc1F -US20070219198A1,6,C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(C2CCN(C(=O)OC(C)(C)C)CC2)c1>>C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(C2CCNCC2)c1 -US20110319385A1,2,CO.O=C(O)c1cc2[nH]c(=O)c3nnc(C4CCOCC4)n3c2cc1Br>>COC(=O)c1cc2[nH]c(=O)c3nnc(C4CCOCC4)n3c2cc1Br -US04424222,2,O=C(Cl)Oc1ccccc1.O=C1Nc2cccnc2Nc2ccccc21>>O=C1Nc2cccnc2N(C(=O)Oc2ccccc2)c2ccccc21 -US20060160821A1,7,CN1CCN(c2ccncc2)C(=O)C1>>CN1CCN(C2CCNCC2)C(=O)C1 -US04036965,8,CCCCSc1ccc(C(=O)OC)nc1.O=C(OO)c1cccc(Cl)c1>>CCCCS(=O)c1ccc(C(=O)OC)nc1 -US08173650B2,1,CC(C)(C)OC(=O)N1CC(=O)C1.FC1(F)CNC1>>CC(C)(C)OC(=O)N1CC(N2CC(F)(F)C2)C1 -US20120077793A1,3,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1F)C(=O)N1CCC[C@H]1C#N.CC(C)c1ccc(CN2CC(Oc3ccc(Br)cn3)C2)cc1>>CC(C)c1ccc(CN2CC(Oc3ccc(-c4ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N5CCC[C@H]5C#N)c(F)c4)cn3)C2)cc1 -US05556864,6,COc1cccc(CCc2ccccc2OCCC2CCN(C(=O)OC(C)(C)C)CC2)c1>>COc1cccc(CCc2ccccc2OCCC2CCNCC2)c1 -US20080076745A1,6,CC(C)(C)OC(=O)N[C@H](CO)CCNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@H](CO)CCN -US05424277,1,BrC1CCCC1.CCOC(=O)Nc1cc(O)c(Cl)cc1F>>CCOC(=O)Nc1cc(OC2CCCC2)c(Cl)cc1F -US08324216B2,1,C1CNCCN1.O=C(c1ccccc1)c1cc(Cl)ccc1Br>>O=C(c1ccccc1)c1cc(Cl)ccc1N1CCNCC1 -US06809199B2,1,CCOP(OCC)OCC.O=C1NCc2c(-c3ccccc3Cl)cc(CBr)cc2N1c1c(Cl)cccc1Cl>>CCOP(=O)(Cc1cc(-c2ccccc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)NC2)OCC -US20070270437A1,7,COC(=O)c1sc(Nc2cc(COC(=O)C(C)(C)C)ccc2[N+](=O)[O-])cc1O[C@H](C)c1ccccc1C(F)(F)F>>COC(=O)c1sc(Nc2cc(COC(=O)C(C)(C)C)ccc2N)cc1O[C@H](C)c1ccccc1C(F)(F)F -US06498172B1,2,COC(=O)CCc1cccc(CNCc2ccc(-c3nccs3)cc2)c1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)CCc1cccc(CN(Cc2ccc(-c3nccs3)cc2)S(=O)(=O)c2ccc(Cl)cc2)c1 -US06149990,2,CO.COc1cc(F)c(C(=O)O)c(F)c1>>COC(=O)c1c(F)cc(OC)cc1F -US05665718,1,CCCCNCCCC.O=C1c2ccccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCN12>>CCCCN(CCCC)Cc1nc(-c2ncn3c2[C@@H]2CCN2C(=O)c2ccccc2-3)no1 -US09102623B2,2,C#CCN.COC(=O)c1ccc(C(F)(F)C(F)F)[nH]c1=O>>C#CCNC(=O)c1ccc(C(F)(F)C(F)F)[nH]c1=O -US20100075952A1,3,COc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1.Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2>>COc1ccc(-c2ccc3c(c2)C(=Cc2[nH]c4c(c2C)C(=O)N(CCN2CCCCC2)CCC4)C(=O)N3)cc1 -US20060004017A1,7,COc1cc(C(N)=O)c([N+](=O)[O-])cc1OCCCN1CCCC1>>COc1cc(C(N)=O)c(N)cc1OCCCN1CCCC1 -US20110124686A1,2,CC(C)(C)C[C@@H](CO)NC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](CC(C)(C)C)NC(=O)OC(C)(C)C)cc1 -US07220876B2,2,Cc1cccc(CO[C@@H]2CCC[C@H](OCCNCCCc3ccccc3)C2)c1C(=O)O.O=C=Nc1ccccc1>>Cc1cccc(CO[C@@H]2CCC[C@H](OCCN(CCCc3ccccc3)C(=O)Nc3ccccc3)C2)c1C(=O)O -US07964739B2,1,Oc1ccc(Cl)cc1[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccccc1Br>>Clc1ccc2c(c1)[C@H]1CN(Cc3ccccc3)C[C@@H]1c1ccccc1O2 -US20110160202A1,7,COC(=O)c1ccc(Oc2nccnc2C2=CN(C(=O)OC(C)(C)C)CCC2)cc1>>COC(=O)c1ccc(Oc2nccnc2C2CCCN(C(=O)OC(C)(C)C)C2)cc1 -US08765730B2,2,CC(C)[C@H](N)CO.Cc1ccccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(C(=O)O)cc1>>Cc1ccccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(C(=O)N[C@H](CO)C(C)C)cc1 -US20080200471A1,7,O=[N+]([O-])c1ccc2c(c1)OCC2>>Nc1ccc2c(c1)OCC2 -US20080176827A1,2,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1C.Cc1ccc(F)c(CS(N)(=O)=O)c1>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3cc(C)ccc3F)CC2)nc1C -US20120289500A1,2,Nn1nc(N2CCOCC2)c2ccccc2c1=O.O=C(O)CC(F)(F)F>>O=C(CC(F)(F)F)Nn1nc(N2CCOCC2)c2ccccc2c1=O -US20150087658A1,2,Cc1cccc(F)c1C(=O)O.Nc1ccccc1>>Cc1cccc(F)c1C(=O)Nc1ccccc1 -US05968944,1,CCc1nn(-c2c(C)cc(C)cc2C)c(CC)c1CO.OCC1Cc2ccccc2CN1>>CCc1nn(-c2c(C)cc(C)cc2C)c(CC)c1CN1Cc2ccccc2C[C@@H]1CO -US20030144333A1,6,CCOC(=O)C(=O)c1sc(Br)cc1Br>>O=C(O)C(=O)c1sc(Br)cc1Br -US03950339,1,N#CCSc1nc(Cl)cc(-c2ccccc2)n1.NCc1ccc2c(c1)OCO2>>N#CCSc1nc(NCc2ccc3c(c2)OCO3)cc(-c2ccccc2)n1 -US07998978B2,2,Cc1cc(C(=O)O)cc2cc(NC3CCC4(CC3)OCCO4)ncc12.NCc1ccccc1>>Cc1cc(C(=O)NCc2ccccc2)cc2cc(NC3CCC4(CC3)OCCO4)ncc12 -US20130331452A1,1,CCOC(=O)c1ccc(C)c(O)c1.Cc1cccc(C)c1CCl>>CCOC(=O)c1ccc(C)c(OCc2c(C)cccc2C)c1 -US20100210687A1,1,CC(C)(C)OC(=O)N1CCC(=O)CC1.N#Cc1ccc(O)c(N)c1>>CC(C)(C)OC(=O)N1CCC(Nc2cc(C#N)ccc2O)CC1 -US04883815,2,CC(=O)NCCCC(=O)c1ccc(Cl)cc1CCC(=O)O.CCOC(=O)CC[C@H](N)C(=O)OCC>>CCOC(=O)CC[C@H](NC(=O)CCc1cc(Cl)ccc1C(=O)CCCNC(C)=O)C(=O)OCC -US08518972B2,7,COC(=O)c1ccc(C=CC2CCOCC2)cc1>>COC(=O)c1ccc(CCC2CCOCC2)cc1 -US08242116B2,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.COCC(O)CCl>>COCC(O)Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1 -US04239759,1,C1COCCN1.CC(O)(CCCl)c1ccccc1-c1ccccc1>>CC(O)(CCN1CCOCC1)c1ccccc1-c1ccccc1 -US20070197551A1,1,Cc1sc2nc([S-])n(N)c(=O)c2c1C.ClCCCN1CCN(c2ccc3ccccc3n2)CC1>>Cc1sc2nc(SCCCN3CCN(c4ccc5ccccc5n4)CC3)n(N)c(=O)c2c1C -US20120015950A1,1,Brc1ccc(Br)nc1.CC(C)(C)OC(=O)NCCC1CCNCC1>>CC(C)(C)OC(=O)NCCC1CCN(c2ccc(Br)cn2)CC1 -US20090275570A1,3,CC(C)(C)OC(=O)N1CCCC(Nc2ncc(C#N)c3sc(Br)cc23)C1.CCCC[Sn](CCCC)(CCCC)c1ccncc1>>CC(C)(C)OC(=O)N1CCCC(Nc2ncc(C#N)c3sc(-c4ccncc4)cc23)C1 -US06143764,2,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C=Nc1ccc(Cl)c(Cl)c1>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(Cl)c(Cl)c4)cc3)c2cc1OC -US04684733,7,O=C(NCc1ccccn1)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F>>O=C(NCC1CCCCN1)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F -US20150210687A1,7,O=Cc1c(Cl)cccc1C1CC1>>OCc1c(Cl)cccc1C1CC1 -US05242914,2,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(N)=O.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1C(N)=O -US20080139558A1,2,O=C(O)C1CC1.O=c1cc(CNc2cccc(Cl)c2)c2ccc(F)c(F)c2[nH]1>>O=C(C1CC1)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)OC(C)(C)C.COCc1ccc(F)c(Br)c1>>COCc1ccc(F)c(C#Cc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)c1 -US20120220585A1,3,Cc1nc2cccc(Cl)c2nc1Cl.OB(O)c1cc(F)ccc1Cl>>Cc1nc2cccc(Cl)c2nc1-c1cc(F)ccc1Cl -US04782055,1,C#CCc1c(C)nc2c(O)cccn12.Cc1cnccc1CCl>>C#CCc1c(C)nc2c(OCc3ccncc3C)cccn12 -US20130053402A1,2,COC(=O)CC(N)c1ccccc1C.O=C(O)c1csc(Br)n1>>COC(=O)CC(NC(=O)c1csc(Br)n1)c1ccccc1C -US20130029991A1,2,CC(=O)Nc1ccccc1N.O=C(O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1>>CC(=O)Nc1ccccc1NC(=O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1 -US06677384B1,7,CCCCCCCCC1(CO)CCCCC1=O>>CCCCCCCCC1(CO)CCCCC1O -US20080300240A1,1,COc1cc(C=O)cc(OC)c1OC.NNC(=O)CC1Sc2ccccc2NC1=O>>COc1cc(/C=N/NC(=O)CC2Sc3ccccc3NC2=O)cc(OC)c1OC -US08367831B2,6,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CCn2c(=O)ccc3ncc(C(F)(F)F)cc32)CC1>>O=c1ccc2ncc(C(F)(F)F)cc2n1CCN1CCC(NCc2cc3c(cn2)OCCO3)CC1 -US20100093865A1,3,C#CCNC(=O)C(F)(F)F.CCCC(CCC)CSc1cccc(Br)c1>>CCCC(CCC)CSc1cccc(C#CCNC(=O)C(F)(F)F)c1 -US20150197486A9,1,CC(C)C(=O)OCCCl.COC(=O)/C=C/C(=O)O>>COC(=O)/C=C/C(=O)OCCOC(=O)C(C)C -US20120129840A1,6,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2ccn(C)c2c1>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1-c1ccc2ccn(C)c2c1 -US07396844B1,6,CCOC(=O)Cc1ccc(O[C@H]2CCN(C(=O)OC(C)(C)C)C2)cc1>>CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(CC(=O)O)cc2)C1 -US08741906B2,1,CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn[nH]c2n1.Clc1cnccc1CBr>>CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nnn(Cc3ccncc3Cl)c2n1 -US07268133B2,1,Clc1ccc(-c2c3ncnc(Cl)c3nn2-c2ccccc2Cl)cc1.OC1CCN(Cc2ccccc2)C1>>Clc1ccc(-c2c3ncnc(OC4CCN(Cc5ccccc5)C4)c3nn2-c2ccccc2Cl)cc1 -US08569292B2,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CCCO)(c2ccccc2)OC1=O.Cc1cc(Br)cc(C)n1>>Cc1cc(-c2ccc([C@H](C)N3CC[C@](CCCO)(c4ccccc4)OC3=O)cc2)cc(C)n1 -US03988457,6,COc1ccc(N2CCN(Cc3ccc4ccccc4c3)CC2)cc1>>Oc1ccc(N2CCN(Cc3ccc4ccccc4c3)CC2)cc1 -US20130303533A1,1,ClCCN1CCOCC1.O=S(=O)(c1ccc(F)cc1)c1nc(Cl)c2cc[nH]c2n1>>O=S(=O)(c1ccc(F)cc1)c1nc(Cl)c2ccn(CCN3CCOCC3)c2n1 -US20140315933A1,2,Nc1nccs1.O=S(=O)(Cl)c1cc(F)c(F)cc1F>>O=S(=O)(Nc1nccs1)c1cc(F)c(F)cc1F -US20140323494A1,2,CN1CCN(Cc2ccc(C(=O)O)cc2)CC1.Nc1ccc(CO)c(Nc2nccc(-c3cccnc3)n2)c1>>CN1CCN(Cc2ccc(C(=O)Nc3ccc(CO)c(Nc4nccc(-c5cccnc5)n4)c3)cc2)CC1 -US20020038025A1,1,CCNCC.CN(c1ccc(OCCCCBr)cc1)S(=O)(=O)c1ccc(C(F)(F)F)cc1>>CCN(CC)CCCCOc1ccc(N(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)cc1 -US05149698,3,Brc1cnccn1.C#CCCCCOCCCCCCBr>>BrCCCCCCOCCCCC#Cc1cnccn1 -US20090298899A1,2,CCOC(=O)Cc1cccc(N)c1.O=C(O)c1csc(Cl)n1>>CCOC(=O)Cc1cccc(NC(=O)c2csc(Cl)n2)c1 -US06242600B1,2,COC(=O)C[C@@H]1NCCN(CC(=O)OC(C)(C)C)C1=O.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>COC(=O)C[C@H]1C(=O)N(CC(=O)OC(C)(C)C)CCN1C(=O)[C@H](C)NC(=O)OCc1ccccc1 -US20150225399A1,2,CCOCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN)c1=O.CS(=O)(=O)Cl>>CCOCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCNS(C)(=O)=O)c1=O -US08022206B2,7,CC(=O)Cc1c(Cl)cccc1Cl>>CC(O)Cc1c(Cl)cccc1Cl -US06887889B2,7,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(I)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(CN)(c2ccc(I)cc2)CC1 -US09157077B2,6,COC(OC)c1ccnc(SC)n1>>CSc1nccc(C=O)n1 -US07910611B2,9,CC(C)(C)C(=O)NC1=NN(C(=O)C(C)(C)C)C(CNS(=O)(=O)CCCCl)(c2ccccc2)S1.[N-]=[N+]=[N-]>>CC(C)(C)C(=O)NC1=NN(C(=O)C(C)(C)C)C(CNS(=O)(=O)CCCN=[N+]=[N-])(c2ccccc2)S1 -US07361670B2,6,COC(=O)c1cc2ccc3[nH]ccc3c2[nH]1>>O=C(O)c1cc2ccc3[nH]ccc3c2[nH]1 -US06403792B1,7,CC(C)(C)OC(=O)N1CCC[C@H]1C=Cc1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1CCc1ccccc1 -US20070037974A1,1,Brc1nccs1.C1CNCCN1>>c1csc(N2CCNCC2)n1 -US20070254882A1,2,C=CCN(C)S(=O)(=O)Cl.CCOC(=O)CNCc1cccc(OCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)c1>>C=CCN(C)S(=O)(=O)N(CC(=O)OCC)Cc1cccc(OCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)c1 -US20120115878A1,1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)nc2)CC1.CN(C)C(=O)c1cc2cnc(Cl)nc2n1C1CCCC1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cn3)nc2n1C1CCCC1 -US05763621,6,CC(C)CC(C(=O)NC(C(=O)NC1CC1)C(C)(C)C)C(CN1C(=O)c2ccccc2C1=O)C(=O)OCc1ccccc1>>CC(C)CC(C(=O)NC(C(=O)NC1CC1)C(C)(C)C)C(CN1C(=O)c2ccccc2C1=O)C(=O)O -US20070060567A1,2,CCOC(=O)c1ccc(N)cc1.COc1ccc(Cl)cc1S(=O)(=O)N1CCCCc2ccc(C(=O)O)cc21>>CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(Cl)ccc2OC)CCCC3)cc1 -US04925879,7,CC(=O)COCCCC(N(C)C)C1(c2ccc(Cl)cc2)CCC1>>CC(O)COCCCC(N(C)C)C1(c2ccc(Cl)cc2)CCC1 -US05596097,1,CN(C)CCN.COc1ccc(COc2cncc3c2C(=O)c2c(F)ccc(Cl)c2C3=O)cc1>>COc1ccc(COc2cncc3c2C(=O)c2c(NCCN(C)C)ccc(Cl)c2C3=O)cc1 -US20110190300A1,2,O=C(Cl)Oc1cccc(C(F)(F)F)c1.O=C1CCNCC1>>O=C1CCN(C(=O)Oc2cccc(C(F)(F)F)c2)CC1 -US06162811,6,Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CCCCC(=O)OCc4ccccc4)ccc3n(C)c12>>Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CCCCC(=O)O)ccc3n(C)c12 -US20040006141A1,6,CCOC(=O)C(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)c([N+](=O)[O-])c1)Oc1ccccc1>>O=C(NCCOc1ccc(CC(Oc2ccccc2)C(=O)O)cc1[N+](=O)[O-])c1ccc(-c2ccccn2)cc1 -US04351940,1,CC[O-].COc1c(Cl)cc2c(Cl)nc(Cl)nc2c1OC>>CCOc1nc(Cl)nc2c(OC)c(OC)c(Cl)cc12 -US20140121206A1,5,CC(C)(C#N)c1cc(N)on1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)Nc1cc(C(C)(C)C#N)no1 -US20100311966A1,2,CCOC(=O)c1sc(N2CCC(NC)CC2)nc1C.CCc1[nH]c(C(=O)O)nc1Cl>>CCOC(=O)c1sc(N2CCC(N(C)C(=O)c3nc(Cl)c(CC)[nH]3)CC2)nc1C -US20150252038A1,1,COC(=O)c1cc(C2CC2)c(OCC2(C)CNC2)cc1F.FC(F)(F)c1cnc(Br)c(Cl)c1>>COC(=O)c1cc(C2CC2)c(OCC2(C)CN(c3ncc(C(F)(F)F)cc3Cl)C2)cc1F -US08501782B2,4,CC1=C(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)C1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CCC2(c3ccc(Cl)cc3)OC2(C)C1 -US20150218112A1,2,CCC(=O)CCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O.COc1nc2ccccc2cc1C(=O)CN>>CCC(=O)CCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)c1cc2ccccc2nc1OC -US20140243335A1,9,COC(=O)c1ccc2c(c1)CC(Nc1ccnc(Cl)c1)CC2>>COC(=O)c1ccc2c(c1)CC(Nc1ccncc1)CC2 -US07235581B2,6,CC(C)(C)OC(=O)N[C@H]1CCN(c2ccc(OCc3ccccc3)cc2)C1=O>>N[C@H]1CCN(c2ccc(OCc3ccccc3)cc2)C1=O -US20120283254A1,2,CS(=O)(=O)Cl.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CS(=O)(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1 -US06140330,6,COC(=O)c1ccc(C=CC(=O)OC(C)(C)C)cc1OC>>COC(=O)c1ccc(C=CC(=O)O)cc1OC -US20140171430A1,6,Cc1noc(-c2c(F)cccc2C(=O)N2CC3CN(C(=O)OC(C)(C)C)CC3C2)n1>>Cc1noc(-c2c(F)cccc2C(=O)N2CC3CNCC3C2)n1 -US07754717B2,6,COC(=O)c1ccc(C)c(C(=O)Nc2ccc(N)nc2)c1>>Cc1ccc(C(=O)O)cc1C(=O)Nc1ccc(N)nc1 -US20100130469A1,6,CC(C)(C)OC(=O)NC1CCN(c2nc(-c3ccncc3)cc3cnccc23)CC1>>NC1CCN(c2nc(-c3ccncc3)cc3cnccc23)CC1 -US08785443B2,2,CCN(CC)C(=O)[C@H](C)O.COC(=O)/C=C/C(=O)O>>CCN(CC)C(=O)[C@H](C)OC(=O)/C=C/C(=O)OC -US07423030B2,3,CON(C)C(=O)c1ccc(C)cc1.COc1ccc(Br)c(C(=O)O)c1>>COc1ccc(C(=O)c2ccc(C)cc2)c(C(=O)O)c1 -US04000275,1,CCN(CC)CCCCBr.Cc1ccc2c(=O)n3c(nc2c1)[nH]c1cc(C)c(C)cc13>>CCN(CC)CCCCn1c2cc(C)c(C)cc2n2c(=O)c3ccc(C)cc3nc12 -US08217021B2,9,CC1=NN(c2ccc(C)c(C)c2)C(=O)/C1=N\Nc1cccc(-c2cccc(C(=O)Cl)c2)c1O.N>>CC1=NN(c2ccc(C)c(C)c2)C(=O)C1=NNc1cccc(-c2cccc(C(N)=O)c2)c1O -US06143764,1,COc1cc2nccc(Cl)c2cc1OC.Cc1ccccc1C(=O)c1ccc(O)cc1>>COc1cc2nccc(Oc3ccc(C(=O)c4ccccc4C)cc3)c2cc1OC -US05354747,7,O=[N+]([O-])c1cc(Cl)ccc1Sc1ccccc1>>Nc1cc(Cl)ccc1Sc1ccccc1 -US20040058959A1,1,CN1CCCNCC1.CSCCOc1cc(F)ccc1C(=O)Nc1ccc(F)cc1C(=O)Nc1ccc(Cl)cn1>>CSCCOc1cc(N2CCCN(C)CC2)ccc1C(=O)Nc1ccc(F)cc1C(=O)Nc1ccc(Cl)cn1 -US04762927,1,CCCCC1=C(Br)c2cc3c(cc2C1)OCO3.CCNCC>>CCCCC1=C(N(CC)CC)c2cc3c(cc2C1)OCO3 -US07109214B2,7,Cc1cccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CC(CN(C)C)C2=O)c1>>Cc1cccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CC(CN(C)C)C2O)c1 -US04424226,2,O=C(O)c1ccncc1.O=C1Nc2cccnc2Nc2ccccc21>>O=C1Nc2cccnc2N(C(=O)c2ccncc2)c2ccccc21 -US07019026B1,6,CCOC(=O)C1Cc2c(sc(N)c2C(=O)OC(C)(C)C)CO1>>CC(C)(C)OC(=O)c1c(N)sc2c1CC(C(=O)O)OC2 -US04332815,2,CC1(C)[C@@H](C(=O)Cl)[C@@H]1C=C(Cl)C(F)(F)F.OCc1cccc(Oc2ccccc2)c1>>CC1(C)[C@@H](C(=O)OCc2cccc(Oc3ccccc3)c2)[C@@H]1C=C(Cl)C(F)(F)F -US04412079,5,CCNC(=S)NN.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCNC(=S)NNC(=O)C(F)(F)F -US20110105530A1,2,Nc1cc(C(=O)NCc2ccccc2)ccn1.O=C(Cl)c1ccccc1F>>O=C(NCc1ccccc1)c1ccnc(NC(=O)c2ccccc2F)c1 -US20090203674A1,1,CCC#CCOc1cc(Cl)ncn1.FC(F)(F)C1CCCNC1>>CCC#CCOc1cc(N2CCCC(C(F)(F)F)C2)ncn1 -US08987284B2,7,O=[N+]([O-])c1ccc2c(cnn2Cc2cccc(F)c2)c1>>Nc1ccc2c(cnn2Cc2cccc(F)c2)c1 -US20130072506A1,1,CNC.OC[C@H]1O[C@@H](n2c(Br)nc3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O>>CN(C)c1nc2c(NCc3ccccc3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O -US20040138273A1,3,O=[N+]([O-])c1ccc(F)cc1Br.OB(O)c1ccc(Cl)cc1Cl>>O=[N+]([O-])c1ccc(F)cc1-c1ccc(Cl)cc1Cl -US08148383B2,7,CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCC(=O)CC2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCC(O)CC2)c2ncnn12 -US20090253681A1,6,Cc1cc(CNC(=O)c2nc3n(c(=O)c2O)CCN(C(=O)OC(C)(C)C)CC3N(C)C(=O)C(=O)N(C)C)ccc1F>>Cc1cc(CNC(=O)c2nc3n(c(=O)c2O)CCNCC3N(C)C(=O)C(=O)N(C)C)ccc1F -US20130331378A1,9,COC(=O)c1cccc(C(O)c2c(N3CCCC3)nn3c([Si](C)(C)C)c(Cl)ccc23)n1>>COC(=O)c1cccc(Cc2c(N3CCCC3)nn3c([Si](C)(C)C)c(Cl)ccc23)n1 -US20150284390A1,3,COC(=O)c1cc(B(O)O)ccc1F.COc1c(C(C)=O)cc(Cl)c(C)c1Br>>COC(=O)c1cc(-c2c(C)c(Cl)cc(C(C)=O)c2OC)ccc1F -US20130005760A1,3,Cc1cc(=O)c2ccc(Br)cc2n1Cc1cccc(F)c1N.Cc1noc(C)c1B1OC(C)(C)C(C)(C)O1>>Cc1noc(C)c1-c1ccc2c(=O)cc(C)n(Cc3cccc(F)c3N)c2c1 -US20100093818A1,2,CCOC(=O)c1ccc(N)cc1.CO[C@@H](c1ccccc1)c1nc2cc(F)c(F)cc2n1C(C(=O)O)C1CCCCC1>>CCOC(=O)c1ccc(NC(=O)C(C2CCCCC2)n2c([C@@H](OC)c3ccccc3)nc3cc(F)c(F)cc32)cc1 -US05994378,9,CCCC(Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1)C(N)=O>>CCCC(C#N)Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1 -US08501758B2,3,CCCS(=O)(=O)Nc1ccc(F)c(B2OC(C)(C)C(C)(C)O2)c1F.COC(=O)N[C@@H](C)CNc1nccc(-c2cn(C(C)C)nc2I)n1>>CCCS(=O)(=O)Nc1ccc(F)c(-c2nn(C(C)C)cc2-c2ccnc(NC[C@H](C)NC(=O)OC)n2)c1F -US08309581B2,6,COc1ccc(COc2ncccc2-c2nc3cc(F)c(F)cc3n2Cc2cccc(Cl)c2)cc1>>Oc1ncccc1-c1nc2cc(F)c(F)cc2n1Cc1cccc(Cl)c1 -US20100226967A1,7,C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2C(=O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO>>C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO -US06080870,1,BrCc1ccccc1.C=CCc1cc(-c2ccccc2C)ccc1O>>C=CCc1cc(-c2ccccc2C)ccc1OCc1ccccc1 -US06982348B2,2,NC(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)NC(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1 -US20020160996A1,7,Cc1oc2c(C)c(C)c(NC(=O)c3ccc(F)cc3)c(C)c2c1-c1ccc(C(C)C)cc1>>Cc1oc2c(C)c(C)c(NCc3ccc(F)cc3)c(C)c2c1-c1ccc(C(C)C)cc1 -US20090239845A1,2,Cc1cc(C(=O)O)nn1Cc1cc(Cl)ccc1OCc1ccccc1.Nc1ccccn1>>Cc1cc(C(=O)Nc2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 -US20070117785A1,6,CCOC(=O)COc1ccccc1NC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(Nc2ccccc2OCC(=O)O)CC1 -US20100113780A1,3,CCCc1nc(C)n(C2CCOCC2)c(=O)c1Cc1ccc(Br)cc1.N#Cc1ccccc1B(O)O>>CCCc1nc(C)n(C2CCOCC2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20110039852A1,2,CCNCc1ccc(C(F)(F)F)cc1-c1cc(CC(=O)OCC)ccc1OC.O=C=NCc1ccccc1>>CCOC(=O)Cc1ccc(OC)c(-c2cc(C(F)(F)F)ccc2CN(CC)C(=O)NCc2ccccc2)c1 -US20150133511A1,4,CCOC(=O)C#Cc1ccc(Br)cc1F.C[Si](C)(C)CN=[N+]=[N-]>>CCOC(=O)c1c(-c2ccc(Br)cc2F)nnn1C[Si](C)(C)C -US20110212053A1,1,CC(C)(C#N)c1ccc(CBr)cc1.Sc1ccccc1>>CC(C)(C#N)c1ccc(CSc2ccccc2)cc1 -US09102625B2,1,CC(=O)N1CCN(c2ccc(N)cc2)CC1.NC(=O)c1cnc(Cl)cc1N[C@@H]1CC[C@H](O)CC1>>CC(=O)N1CCN(c2ccc(Nc3cc(N[C@@H]4CC[C@H](O)CC4)c(C(N)=O)cn3)cc2)CC1 -US20140038989A1,2,CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)O)c3N2)cc1.Cc1cnc(CN)c(F)c1>>CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)NCc4ncc(C)cc4F)c3N2)cc1 -US20070135442A1,1,CCOC1CCNCC1.O=[N+]([O-])c1ccc(F)cc1>>CCOC1CCN(c2ccc([N+](=O)[O-])cc2)CC1 -US05034417,7,CC(=O)c1ccc(NS(C)(=O)=O)c(Sc2ccc(Cl)cc2Cl)c1>>CC(O)c1ccc(NS(C)(=O)=O)c(Sc2ccc(Cl)cc2Cl)c1 -US20090036492A1,1,CC#CCOc1cc(C)c(C=O)c(C)c1C.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CC#CCOc1cc(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c(C)c1C -US07649002B2,2,CC(C)(C)OC(=O)OC(=O)/C=C/c1ccc(F)cc1F.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(/C=C/c1ccc(F)cc1F)N1C(=O)OC[C@@H]1Cc1ccccc1 -US08188101B2,1,CC(=O)N1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(OS(=O)(=O)C(F)(F)F)c2C1.OCC1CCCNC1>>CC(=O)N1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(N3CCCC(CO)C3)c2C1 -US04595699,7,CC(C(=O)O)c1ccc(CC2CCCCC2=O)cc1>>CC(C(=O)O)c1ccc(C[C@@H]2CCCC[C@@H]2O)cc1 -US06800778B1,7,CCOC(=O)C1(C(O)c2ccccc2Cl)CCCC1>>OCC1(C(O)c2ccccc2Cl)CCCC1 -US05580888,1,BrC1CCCC1.COc1ccc(C=O)cc1O>>COc1ccc(C=O)cc1OC1CCCC1 -US07838522B2,7,COC(=O)c1ccnc(N2CCCCC2)c1>>OCc1ccnc(N2CCCCC2)c1 -US05426111,1,CI.OC1(C#CCOC2CCCCO2)CCOCC1>>COC1(C#CCOC2CCCCO2)CCOCC1 -US20120289500A1,2,CN1CCN(c2nn(N)c(=O)c3ccccc23)CC1.O=C(Cl)Cc1ccc(Cl)cc1>>CN1CCN(c2nn(NC(=O)Cc3ccc(Cl)cc3)c(=O)c3ccccc23)CC1 -US07544812B2,6,CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3cccc(C(F)(F)F)c3)C(=O)N2C)cc1)Oc1ccccc1>>CN1C(=O)N(Cc2cccc(C(F)(F)F)c2)CC1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 -US20080004348A1,2,C=CCC(=O)O.COc1ccc2cccc(C(CN)CO)c2c1>>C=CCC(=O)NCC(CO)c1cccc2ccc(OC)cc12 -US20100311777A1,2,COC(=O)C1(N)CCN(OC)CC1.Cc1cc(C)c(C2CC2)cc1CC(=O)Cl>>COC(=O)C1(NC(=O)Cc2cc(C3CC3)c(C)cc2C)CCN(OC)CC1 -US07750155B2,1,COC(=O)/C=C/c1cnc(N[C@@H]2CCNC2)cn1.O=Cc1cccc2ccccc12>>COC(=O)/C=C/c1cnc(N[C@@H]2CCN(Cc3cccc4ccccc34)C2)cn1 -US20070191420A1,7,N#Cc1ccc(-c2nc3ccncc3[nH]2)cc1>>NCc1ccc(-c2nc3ccncc3[nH]2)cc1 -US06080781,3,COc1cc(C=O)cc(OC)c1.O=C1CCCc2cc(O)ccc21>>COc1cc(C=C2CCc3cc(O)ccc3C2=O)cc(OC)c1 -US20140343079A1,6,CCOC(=O)/C=C/c1ccc(C)c(-c2cc3c(cc2C)C(C)(C)CCC3(C)C)c1>>Cc1ccc(/C=C/C(=O)O)cc1-c1cc2c(cc1C)C(C)(C)CCC2(C)C -US05646313,2,CC(=O)SC/C(=C\c1ccccc1)C(=O)O.NCCC(=O)OCc1ccccc1>>CC(=O)SC/C(=C\c1ccccc1)C(=O)NCCC(=O)OCc1ccccc1 -US20100063068A1,3,C#Cc1ccc(F)cc1.COCOc1cnc(OCc2ccccc2)cc1I>>COCOc1cnc(OCc2ccccc2)cc1C#Cc1ccc(F)cc1 -US20130324542A1,2,COc1ccc2c(OCC(=O)O)ccnc2c1.NNc1ncc(-c2cccs2)nn1>>COc1ccc2c(OCC(=O)NNc3ncc(-c4cccs4)nn3)ccnc2c1 -US20070191334A1,2,C=CCc1c(C(=O)N(C)C)cn2cc(C)nc2c1O.CC(C)(C)C(=O)Cl>>C=CCc1c(C(=O)N(C)C)cn2cc(C)nc2c1OC(=O)C(C)(C)C -US04975438,1,CCCCCC(=CC=CC(=O)O)CCCCC.O=[N+]([O-])c1ccc(O)cc1>>CCCCCC(=CC=CC(=O)Oc1ccc([N+](=O)[O-])cc1)CCCCC -US20080027050A1,6,CCOC(=O)c1ccc(COCc2csc3nc(C(=O)NCc4cccc(CC)c4)[nH]c(=O)c23)cc1>>CCc1cccc(CNC(=O)c2nc3scc(COCc4ccc(C(=O)O)cc4)c3c(=O)[nH]2)c1 -US08957070B2,2,NN.O=C(O)c1cc2cccc(NS(=O)(=O)c3cccs3)c2[nH]1>>NNC(=O)c1cc2cccc(NS(=O)(=O)c3cccs3)c2[nH]1 -US20140375943A1,3,O=C(O)c1ccc(Br)cc1.OB(O)c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1>>O=C(O)c1ccc(-c2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)cc1 -US20090270625A1,1,COC(=O)c1ccc(F)cc1.Cc1c[nH]cn1>>COC(=O)c1ccc(-n2cnc(C)c2)cc1 -US20080091031A1,7,COC(=O)c1cc([N+](=O)[O-])cc(S(F)(F)(F)(F)F)c1>>COC(=O)c1cc(N)cc(S(F)(F)(F)(F)F)c1 -US20140274689A1,3,Brc1cnn(-c2ccccc2)c1.OB(O)c1ccco1>>c1ccc(-n2cc(-c3ccco3)cn2)cc1 -US04532367,3,Cc1cccc(Br)c1O.ClCc1ccccc1>>Cc1cc(Cc2ccccc2)cc(Br)c1O -US08772492B2,6,CCc1ccc(NC(=O)[C@@H]2C[C@@H](Nc3ccc4cnccc4c3)CN2C(=O)OC(C)(C)C)cc1>>CCc1ccc(NC(=O)[C@@H]2C[C@@H](Nc3ccc4cnccc4c3)CN2)cc1 -US07638648B2,3,C#Cc1cc(C2CC2)c2c(c1)C(C)(C)CCC2=O.CCOC(=O)/C=C/c1ccc(I)cc1>>CCOC(=O)C=Cc1ccc(C#Cc2cc(C3CC3)c3c(c2)C(C)(C)CCC3=O)cc1 -US08563570B2,2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=C1N([C@@H]2CC[C@@H](O)CC2)CCC12CCCNC2>>O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCCC2(CCN([C@@H]3CC[C@@H](O)CC3)C2=O)C1 -US07754712B2,3,CC1C(=O)CC2CCCC1N2S(=O)(=O)c1ccc(Cl)cc1.CN(C)C=O>>CC1C(=O)C(=CN(C)C)C2CCCC1N2S(=O)(=O)c1ccc(Cl)cc1 -US20140288067A1,1,C1COCCN1.Cc1c(Cl)nc(-c2cccc(O)c2)nc1N[C@@H]1CCOC1>>Cc1c(N[C@@H]2CCOC2)nc(-c2cccc(O)c2)nc1N1CCOCC1 -US20140142083A1,7,COC(=O)c1cccc([N+](=O)[O-])c1C>>COC(=O)c1cccc(N)c1C -US03962321,9,CCCCCC/C=C/C(=O)Cl>>CCCCCC/C=C/C=O -US20090312327A1,2,CNC1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)c(Cl)c1.O=C(O)c1ccc(Cl)c(C(F)(F)F)c1>>CN(C(=O)c1ccc(Cl)c(C(F)(F)F)c1)C1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)c(Cl)c1 -US05486525,1,C=[N+]=[N-].O=C(O)c1cccc2[nH]ccc12>>COC(=O)c1cccc2[nH]ccc12 -US20090274655A1,1,COC(=O)c1sccc1N.O=C1CCC1>>COC(=O)c1sccc1NC1CCC1 -US05750705,9,C#CCOc1nc(F)c(C(F)(F)F)cc1Cl.N>>C#CCOc1nc(N)c(C(F)(F)F)cc1Cl -US07645771B2,2,Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2ccccc2)CCNCC1.N#CC1(C(=O)O)CC1>>Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2ccccc2)CCN(C(=O)C2(C#N)CC2)CC1 -US20120071460A1,6,COCCc1c(C(=O)OC)cnn1C1CCCCC1>>COCCc1c(C(=O)O)cnn1C1CCCCC1 -US06140512,5,CCOC(=O)CC1CCCCC1=O.OCCO>>CCOC(=O)CC1CCCCC12OCCO2 -US20080139558A1,1,Nc1cccc(Cl)c1.O=c1cc(CBr)c2cccc(F)c2[nH]1>>O=c1cc(CNc2cccc(Cl)c2)c2cccc(F)c2[nH]1 -US20100249123A1,2,CC(=O)NCCC(C)(C)c1ccc(N)cc1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CCNC(C)=O)cc2)cc1OC -US07932272B2,3,Brc1ccc(C2OCCO2)s1.Fc1cccc(CBr)c1>>Fc1cccc(Cc2ccc(C3OCCO3)s2)c1 -US20090163471A1,1,CC(=O)c1c(F)cc(Br)cc1F.N>>CC(N)c1c(F)cc(Br)cc1F -US20060160794A1,7,Clc1ccccc1C1=CCCN1>>Clc1ccccc1[C@H]1CCCN1 -US20130053373A1,6,CC(C)(C)OC(=O)NC1=N[C@@]2(c3ccccc3F)CO[C@@H](CF)C[C@H]2CS1>>NC1=N[C@@]2(c3ccccc3F)CO[C@@H](CF)C[C@H]2CS1 -US08921397B2,2,CC(C)CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1>>CC(C)CC(=O)N[C@@H]1CC[C@@H](CCN2CCCCC2c2coc3cccc-3c2)CC1 -US04293485,2,CCCCCCCCCCCC(=O)Cl.Nc1ccc(C(=O)O)cc1>>CCCCCCCCCCCC(=O)Nc1ccc(C(=O)O)cc1 -US20110172247A1,1,Clc1cncc(Cl)n1.Oc1cccnc1>>Clc1cncc(Oc2cccnc2)n1 -US20120245161A1,6,COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)C(F)(F)F)ccc3F)CC2)c2c(Cl)cccc21>>COCCn1cc(C(=O)N2CCC(c3cc(CN)ccc3F)CC2)c2c(Cl)cccc21 -US20070149577A1,2,COc1cc(C(C)N)ccc1-c1cccnc1OC.O=S(=O)(Cl)c1ccccc1OC(F)(F)F>>COc1cc([C@@H](C)NS(=O)(=O)c2ccccc2OC(F)(F)F)ccc1-c1cccnc1OC -US07390903B2,4,BrCCCCCBr.Cc1nc2sc3c(c2c(N)c1C(=O)C1CC1)CCC3>>Cc1nc2sc3c(c2c(N2CCCCC2)c1C(=O)C1CC1)CCC3 -US07259183B2,1,CC(C)(C)c1ccc(C=O)cc1.NCCc1ccc(OC(F)F)cc1>>CC(C)(C)c1ccc(CNCCc2ccc(OC(F)F)cc2)cc1 -US08394858B2,6,C[C@@H](NC(=O)C1(NC(=O)OC(C)(C)C)CCC(NCc2ccccc2)CC1)c1ccc(F)cc1>>C[C@@H](NC(=O)C1(NC(=O)OC(C)(C)C)CCC(N)CC1)c1ccc(F)cc1 -US04138579,1,C#CCBr.CCC(C)=CCCC(CC)Oc1ccc(C(=O)O)cc1>>C#CCOC(=O)c1ccc(OC(CC)CCC=C(C)CC)cc1 -US20140275172A1,1,Cc1c(O)ccc(CCC(=O)OC(C)(C)C)c1C.OCc1cc(F)cc2sc(C(F)(F)F)nc12>>Cc1c(CCC(=O)OC(C)(C)C)ccc(OCc2cc(F)cc3sc(C(F)(F)F)nc23)c1C -US06319902B1,6,CCCCCCCCCCCCCCOC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cscn1)NC(=O)OC(C)(C)C>>CCCCCCCCCCCCCCOC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1cscn1 -US06344462B1,7,COC(=O)C=Cc1ccc(C(=O)O)cc1>>COC(=O)CCc1ccc(C(=O)O)cc1 -US20090264445A1,1,ClCc1ccccc1.O=C(O)[C@@H](O)Cc1ccc(O)cc1>>O=C(O)[C@@H](O)Cc1ccc(OCc2ccccc2)cc1 -US08466289B2,2,Cc1c(Nc2ccc(I)cc2F)c(N)c2n(c1=O)CCO2.O=S(=O)(Cl)C1(COCc2ccccc2)CC1>>Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2(COCc3ccccc3)CC2)c2n(c1=O)CCO2 -US20130216498A1,6,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(N3CCN(C(=O)OCc4ccccc4)CC3)nc(-c3cnc4ccc(F)cn34)n2)C1>>O=C(OCc1ccccc1)N1CCN(c2cc(N[C@@H]3CCCNC3)nc(-c3cnc4ccc(F)cn34)n2)CC1 -US20080312234A1,2,CCNc1nc(C(F)(F)F)ccc1C=CC(=O)O.Cc1cc(CN)cc(F)c1NS(C)(=O)=O>>CCNc1nc(C(F)(F)F)ccc1C=CC(=O)NCc1cc(C)c(NS(C)(=O)=O)c(F)c1 -US05380721,7,Cn1nc(-c2ccc([N+](=O)[O-])cc2)c2ccccc2c1=O>>Cn1nc(-c2ccc(N)cc2)c2ccccc2c1=O -US20130289033A1,3,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1.OB(O)c1ccc(C(F)(F)F)cc1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(-c2ccc(C(F)(F)F)cc2)c1 -US20110046134A1,6,O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cc(-c2cccc(OCc3ccccc3)c2)[nH]n1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cc(-c2cccc(O)c2)[nH]n1 -US05459160,1,CCOC(C)O[C@@H]1OC=C(C(=O)OC)[C@H]2CC=C(CO)[C@H]21.CI>>CCOC(C)O[C@@H]1OC=C(C(=O)OC)[C@H]2CC=C(COC)[C@H]21 -US20110313002A1,2,CCOC(=O)C1Oc2cccc(OC)c2C=C1CN[C@@H](CC(C)C)C(=O)OC>>COC(=O)[C@H](CC(C)C)N1CC2=Cc3c(OC)cccc3OC2C1=O -US04138258,2,CCC(C)(C)c1ccc(OCCCN)c(C(C)(C)CC)c1.CCOc1cc(C(=O)O)c(O)c2ccccc12>>CCOc1cc(C(=O)NCCCOc2ccc(C(C)(C)CC)cc2C(C)(C)CC)c(O)c2ccccc12 -US20110263593A1,2,Nc1nc2ccc(Sc3cnc4ncccn34)cc2s1.O=C(O)C1CCOCC1>>O=C(Nc1nc2ccc(Sc3cnc4ncccn34)cc2s1)C1CCOCC1 -US04803225,2,COc1ccc(CCNC(=O)CCCCC(=O)O)cc1OC.NCCNc1ccccc1>>COc1ccc(CCNC(=O)CCCCC(=O)NCCNc2ccccc2)cc1OC -US08735584B2,1,Nc1cccc(C(F)(F)F)c1.O=c1[nH]c2ncccc2c2cc(Cl)ccc12>>O=c1[nH]c2ncccc2c2cc(Nc3cccc(C(F)(F)F)c3)ccc12 -US20050203087A1,1,CCOC(=O)CBr.COC(=O)c1sc(Br)c(C)c1O>>CCOC(=O)COc1c(C(=O)OC)sc(Br)c1C -US20150232452A1,9,CCn1cc(Br)c(-c2ccnc(SC)n2)n1>>CCn1ccc(-c2ccnc(SC)n2)n1 -US20060074119A1,1,CN(C)CCCO.COC(=O)c1sc(-n2cnc3cc(OC)c(O)cc32)cc1OCc1ccccc1C(F)(F)F>>COC(=O)c1sc(-n2cnc3cc(OC)c(OCCCN(C)C)cc32)cc1OCc1ccccc1C(F)(F)F -US08269002B2,1,C[C@H](COC(c1ccccc1)(c1ccccc1)c1ccccc1)Oc1cc(Cl)nc(SCc2cccc(F)c2F)n1.NS(=O)(=O)c1ccncc1>>C[C@H](COC(c1ccccc1)(c1ccccc1)c1ccccc1)Oc1cc(NS(=O)(=O)c2ccncc2)nc(SCc2cccc(F)c2F)n1 -US07521464B2,6,CC(NC(=O)OC(C)(C)C)C(=O)Nc1cc(-c2ccccc2)n[nH]1>>CC(N)C(=O)Nc1cc(-c2ccccc2)n[nH]1 -US05597820,6,CC[C@H]1Oc2cc(C(=O)OC)ccc2N(C(C)C)C1=O>>CC[C@H]1Oc2cc(C(=O)O)ccc2N(C(C)C)C1=O -US08785653B2,1,CI.Cc1cccc2nc(CSc3nc(-c4ccccc4)n[nH]3)nn12>>Cc1cccc2nc(CSc3nc(-c4ccccc4)nn3C)nn12 -US04551532,1,CCCCCCCCCCCCCCBr.OCCOCCO>>CCCCCCCCCCCCCCOCCOCCO -US05852017,2,CC(=O)OC(C)=O.CCn1c(=O)c(=O)[nH]c2ccc(N)cc21>>CCn1c(=O)c(=O)[nH]c2ccc(NC(C)=O)cc21 -US08183262B2,1,Brc1c[nH]cn1.Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(Cl)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(-n2cnc(Br)c2)n1 -US06953793B2,1,CC(=O)N1CCc2[nH]nc(-c3ccc(Br)cc3)c2C1.ClCC1CO1>>CC(=O)N1CCc2c(c(-c3ccc(Br)cc3)nn2CC2CO2)C1 -US07799785B2,9,[N-]=[N+]=N[C@@H]1CO[C@H]2c3cc(F)ccc3Cc3ccccc3[C@H]2C1>>N[C@@H]1CO[C@H]2c3cc(F)ccc3Cc3ccccc3[C@H]2C1 -US20140051703A1,1,COC(=O)c1ccc(S)cc1.Clc1ccnc(Cl)n1>>COC(=O)c1ccc(Sc2ccnc(Cl)n2)cc1 -US05182263,10,Cc1ccc(C(=O)OC(C)(C)C)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1ccc(CBr)cc1 -US20040167128A1,6,COC(=O)c1c(N(C)S(=O)(=O)c2ccccc2NCC2CCNCC2)ccc2c1CCCC2>>CN(c1ccc2c(c1C(=O)O)CCCC2)S(=O)(=O)c1ccccc1NCC1CCNCC1 -US07262212B2,2,C[C@]1(CN2CCNCC2)Cn2cc([N+](=O)[O-])nc2O1.O=C=NC1CCCCC1>>C[C@]1(CN2CCN(C(=O)NC3CCCCC3)CC2)Cn2cc([N+](=O)[O-])nc2O1 -US05763489,3,CC(C)(C)c1cccc2c1CCC(=O)C2(CCOC(=O)N(c1ccccc1)c1ccccc1)O[SiH](c1ccccc1)c1ccccc1.C[Mg+]>>CC(C)(C)c1cccc2c1CCC(C)(O)C2(CCOC(=O)N(c1ccccc1)c1ccccc1)O[SiH](c1ccccc1)c1ccccc1 -US06211177B1,6,CCOC(=O)c1ccc2c(c1)nc(Cc1ccccc1)n2Cc1ccc(Cl)cc1Cl>>O=C(O)c1ccc2c(c1)nc(Cc1ccccc1)n2Cc1ccc(Cl)cc1Cl -US03956316,1,C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C)C(=O)CC[C@@H]12.O=CO>>C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](OC=O)C[C@]2(C)C(=O)CC[C@@H]12 -US20060100219A1,1,CN(CCN(CCCCl)C(=O)NCCc1ccc(C#N)cc1)S(=O)(=O)c1cccc(Cl)c1Cl>>CN(CCN1CCCN(CCc2ccc(C#N)cc2)C1=O)S(=O)(=O)c1cccc(Cl)c1Cl -US20130053366A1,1,CN.Cc1ccc2c(c1)c1c(n2CC(OS(C)(=O)=O)c2ccncc2)CCN(C)C1>>CNC(Cn1c2c(c3cc(C)ccc31)CN(C)CC2)c1ccncc1 -US20040063959A1,6,CC(C)(C)OC(=O)N[C@@H](CCCC(=O)OCc1ccccc1)C(=O)O[C@H](CC(N)=O)Cc1ccc2ccccc2c1>>NC(=O)C[C@H](Cc1ccc2ccccc2c1)OC(=O)[C@@H](N)CCCC(=O)OCc1ccccc1 -US20070249670A1,6,COC(=O)[C@@H]1CN(S(C)(=O)=O)CCN1C(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C>>Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N2CCN(S(C)(=O)=O)C[C@H]2C(=O)O)c(C)c1 -US06660735B2,1,CC(C)(C)OC(=O)N1CCC(CCI)CC1.CCC(CO)n1cnc2cnc3ccccc3c21>>CCC(COCCC1CCN(C(=O)OC(C)(C)C)CC1)n1cnc2cnc3ccccc3c21 -US08093302B2,1,CI.COc1ccc(C2C(CO)c3ccc(OC)cc3C3CCCCC32)cc1>>COCC1c2ccc(OC)cc2C2CCCCC2C1c1ccc(OC)cc1 -US04010178,2,CC(C)(C)O.N#CC(=NOC(=O)Cl)c1ccccc1>>CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1 -US04636512,6,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)c1nc2c(C(F)(F)F)cccc2c(O)c1C(=O)Nc1nccs1>>N[C@@H](Cc1c[nH]c2ccccc12)c1nc2c(C(F)(F)F)cccc2c(O)c1C(=O)Nc1nccs1 -US07999006B2,2,C[C@@H](NC(=O)OC(C)(C)C)C1(O)CNC1.O=C(F)c1ccc(F)c(F)c1Nc1ccc(I)cc1F>>C[C@@H](NC(=O)OC(C)(C)C)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 -US08927587B2,7,CCC(C)(C)c1ccc(N)c([N+](=O)[O-])c1>>CCC(C)(C)c1ccc(N)c(N)c1 -US20090137549A1,2,CC(=O)OC(C)=O.Oc1ccc(N2CCNCC2)cc1>>CC(=O)N1CCN(c2ccc(O)cc2)CC1 -US06127354,2,CC(C)(C/C=C/C(=O)O)NC(=O)OC(C)(C)C.CNC(=O)[C@@H](Cc1ccccc1)N1C[C@@H](Cc2ccc3ccccc3c2)NCC1=O>>CNC(=O)[C@@H](Cc1ccccc1)N1C[C@@H](Cc2ccc3ccccc3c2)N(C(=O)/C=C/CC(C)(C)NC(=O)OC(C)(C)C)CC1=O -US20080167307A1,6,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(N3CCN(c4ccccc4)CC3)cc2)cs1>>CC(C)(Sc1nc(CCOc2ccc(N3CCN(c4ccccc4)CC3)cc2)cs1)C(=O)O -US20080119555A1,3,O=S(=O)(NCCCCO)c1ccc(Br)c(F)c1.OB(O)c1ccc(C(F)(F)F)cc1>>O=S(=O)(NCCCCO)c1ccc(-c2ccc(C(F)(F)F)cc2)c(F)c1 -US20130217666A1,3,C#CC(C)(O)C1(C)CC1.NC(=O)c1cn2c(n1)-c1cc(Br)c(F)cc1OCC2>>CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)C1(C)CC1 -US06838463B2,1,C#CCOc1cc(Cl)ncn1.Oc1cccc(Cl)c1Cl>>C#CCOc1cc(Oc2cccc(Cl)c2Cl)ncn1 -US20100063053A1,6,COC(=O)c1cc(Br)c(=O)n(C)c1Nc1ccc(Br)cc1F>>Cn1c(Nc2ccc(Br)cc2F)c(C(=O)O)cc(Br)c1=O -US20120142665A1,2,CCN.Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccn2nc(C(=O)O)nc2c1>>CCNC(=O)c1nc2cc(NC(=O)c3c(C(=O)N4CCC4)cnn3C)ccn2n1 -US20130310384A1,1,C[C@H](O)[C@H](CO)NS(=O)(=O)c1ccc(Cl)cc1.Fc1cc(OC(F)F)ccc1CBr>>C[C@H](O)[C@H](CO)N(Cc1ccc(OC(F)F)cc1F)S(=O)(=O)c1ccc(Cl)cc1 -US20140107139A1,1,CC1(C)OCc2ccc(O)cc21.O=[N+]([O-])c1ccc(F)cc1>>CC1(C)OCc2ccc(Oc3ccc([N+](=O)[O-])cc3)cc21 -US05731315,2,N#Cc1cccc(CN2CC[C@H](N)C2=O)c1.O=S(=O)(Cl)c1cc2ccccc2s1>>N#Cc1cccc(CN2CC[C@H](NS(=O)(=O)c3cc4ccccc4s3)C2=O)c1 -US04424351,1,O=C(Cl)c1ccco1.c1ccc(C2=NNc3ccncc3N2)cc1>>O=C(c1ccco1)N1N=C(c2ccccc2)Nc2cnccc21 -US20090042929A1,2,NCCc1cccs1.O=C(Cl)C1CCCCC1>>O=C(NCCc1cccs1)C1CCCCC1 -US08309581B2,1,N#Cc1ccc(CBr)cc1F.Oc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2n1CC1CCCCC1>>N#Cc1ccc(COc2cc(Cl)ccc2-c2nc3cc(F)c(F)cc3n2CC2CCCCC2)cc1F -US20040132716A1,6,O=C(N[C@H](Cc1ccc2c(c1)CCCC2)C(=O)N1CCC(N2CCN(Cc3ccccc3)CC2)CC1)N1CCC(n2nc(-c3ccccc3)[nH]c2=O)CC1>>O=C(N[C@H](Cc1ccc2c(c1)CCCC2)C(=O)N1CCC(N2CCNCC2)CC1)N1CCC(n2nc(-c3ccccc3)[nH]c2=O)CC1 -US20050250943A1,2,CS(=O)(=O)Cl.O=S(=O)(c1ccccc1)c1ccc2c(c1)O[C@H](CO)CO2>>CS(=O)(=O)OC[C@@H]1COc2ccc(S(=O)(=O)c3ccccc3)cc2O1 -US08314100B2,2,CCOC(=O)Nc1nc2ccc(OC)cc2nc1OC.Cc1ccccc1N1CCNCC1>>COc1ccc2nc(NC(=O)N3CCN(c4ccccc4C)CC3)c(OC)nc2c1 -US06211227B1,6,CC(=O)Nc1cccc2c1C(=O)c1sccc1CS2>>Nc1cccc2c1C(=O)c1sccc1CS2 -US06350749B1,4,CCC(=O)C1C(=O)CC(c2ccccc2Cl)CC1=O.NN>>CCc1n[nH]c2c1C(=O)CC(c1ccccc1Cl)C2 -US08420231B2,1,BrCCCCn1c2ccccc2c2ccccc21.CC(=O)[O-]>>CC(=O)OCCCCn1c2ccccc2c2ccccc21 -US05753664,1,Cn1ncc2[nH]ccc2c1=O.O=C(c1ccc(Cl)cc1)c1ccc(CBr)cc1>>Cn1ncc2c(ccn2Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)c1=O -US06087380,2,COC(=O)CCNc1ccccc1.N#Cc1ccc(CCc2ncc3ccc(C(=O)O)cc3n2)cc1>>COC(=O)CCN(C(=O)c1ccc2cnc(CCc3ccc(C#N)cc3)nc2c1)c1ccccc1 -US20060247439A1,1,CC(C)(C)OC(=O)N[C@H]1CC[C@H](N)C1.COc1ccc2nc(Cl)cc(C)c2c1>>COc1ccc2nc(N[C@H]3CC[C@H](NC(=O)OC(C)(C)C)C3)cc(C)c2c1 -US20150218173A1,3,Brc1c[nH]c2ncnc(Nc3ccc4[nH]ncc4c3)c12.CC1(C)OB(C2=CCOCC2)OC1(C)C>>C1=C(c2c[nH]c3ncnc(Nc4ccc5[nH]ncc5c4)c23)CCOC1 -US20140296256A1,3,COC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(I)c1.OB(O)c1cnc2ccccc2c1>>COC(=O)c1cc(Cl)ccc1NC(=O)c1cccc(-c2cnc3ccccc3c2)c1 -US20040058903A1,2,CC(C)(C)[Si](C)(C)OCCc1ccc(N)cc1.O=C(Cl)c1ccccc1-c1ccc(C(F)(F)F)cc1>>CC(C)(C)[Si](C)(C)OCCc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1 -US08138197B2,6,CC(=O)n1nc(C)c2cc(Br)ccc21>>Cc1n[nH]c2ccc(Br)cc12 -US06127354,1,CCOC(=O)CBr.CNC(=O)Cc1ccccc1O>>CCOC(=O)COc1ccccc1CC(=O)NC -US05576324,2,C[C@H](NC(=O)OCc1ccccc1)C(=O)O.Cc1cc2c(c3ccc(=O)[nH]c13)OC(CN)C2>>Cc1cc2c(c3ccc(=O)[nH]c13)OC(CNC(=O)[C@H](C)NC(=O)OCc1ccccc1)C2 -US20150232452A1,2,CCn1cc(-c2cccc(N)c2)c(-c2ccncc2)n1.O=C=Nc1ccc(Br)cc1>>CCn1cc(-c2cccc(NC(=O)Nc3ccc(Br)cc3)c2)c(-c2ccncc2)n1 -US08269011B2,1,CCCI.O=[N+]([O-])c1cc(F)ccc1O>>CCCOc1ccc(F)cc1[N+](=O)[O-] -US20070259911A1,2,CCCC(=O)Cl.COc1cccc(C(=O)Nc2sc3c(c2C#N)CCNC3)c1>>CCCC(=O)N1CCc2c(sc(NC(=O)c3cccc(OC)c3)c2C#N)C1 -US05190959,2,Nc1ccccc1OCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccccc1OCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1)c1ccccc1 -US20100069629A1,1,C1COCCN1.Cc1cc(F)ccc1[N+](=O)[O-]>>Cc1cc(N2CCOCC2)ccc1[N+](=O)[O-] -US04178380,2,C=CCN.O=C(O)C1CCc2cc(C3CCCCC3)ccc2O1>>C=CCNC(=O)C1CCc2cc(C3CCCCC3)ccc2O1 -US20100216798A1,2,COC(=O)c1cnc2ccc(N[C@@H]3CC[C@@H](O)CC3)nn12.Nc1ccccc1>>O=C(Nc1ccccc1)c1cnc2ccc(N[C@@H]3CC[C@@H](O)CC3)nn12 -US20110059043A1,2,CC(=O)Cl.COC(=O)c1cc(Cl)ccc1OCCCN>>COC(=O)c1cc(Cl)ccc1OCCCNC(C)=O -US20120083470A1,6,O=P1(c2ccccc2)CCN(Cc2ccccc2)CC1>>O=P1(c2ccccc2)CCNCC1 -US20030078251A1,6,CCOC(=O)CCc1ccc(NC(C)=O)cc1>>CCOC(=O)CCc1ccc(N)cc1 -US20140336106A1,6,C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1>>C[C@H](N)C(=O)N[C@@H](CC1CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 -US20100099694A1,1,CN1CCC(N(C)S(=O)(=O)c2ccc(Nc3nccc(Cl)n3)cc2)CC1.Fc1ccc2c(c1)CCN2>>CN1CCC(N(C)S(=O)(=O)c2ccc(Nc3nccc(N4CCc5cc(F)ccc54)n3)cc2)CC1 -US20060025400A1,5,NCCc1ccc(Br)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCc1ccc(Br)cc1)C(F)(F)F -US04835175,6,CCOC(=O)c1cc2cccc(OCc3ccccc3)c2[nH]1>>CCOC(=O)c1cc2cccc(O)c2[nH]1 -US20030073850A1,9,O=C(O)c1cccc([N+](=O)[O-])c1Cl>>O=Cc1cccc([N+](=O)[O-])c1Cl -US20150073011A1,7,CC1=C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OC(C)(C)C)CC1=O>>CC1=C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OC(C)(C)C)C[C@H]1O -US20090181942A1,7,COC(=O)/C=C/c1cccn1-c1ccc(Cl)cc1C(=O)c1c(F)ccc(OC)c1OC>>COC(=O)/C=C/c1cccn1-c1ccc(Cl)cc1C(O)c1c(F)ccc(OC)c1OC -US20070117856A1,3,CS(=O)(=O)Nc1cc(C=O)ccc1OCCN1CCOCC1.c1ccc([P+](Cc2n[nH]c3ccccc23)(c2ccccc2)c2ccccc2)cc1>>CS(=O)(=O)Nc1cc(/C=C/c2n[nH]c3ccccc23)ccc1OCCN1CCOCC1 -US08518943B2,9,CCCC1CC(=O)N(Cn2cnc3c(Cl)ncnc32)C1.[NH4+]>>CCCC1CC(=O)N(Cn2cnc3c(N)ncnc32)C1 -US20110105509A1,1,COC(=O)C1=NNC(=O)CC1.FC(F)(F)CCCBr>>COC(=O)C1=NN(CCCC(F)(F)F)C(=O)CC1 -US20090149501A1,3,CC1(C)C(C(=O)Cl)C1(C)C.Cc1cc2ccccc2[nH]1>>Cc1[nH]c2ccccc2c1C(=O)C1C(C)(C)C1(C)C -US20150038488A1,1,COc1ccc([C@@H](C)N2C[C@H]([C@@H](C)O)CC2=O)cc1.Cc1nc2cc(Cl)nc(Cl)c2n1C>>COc1ccc([C@@H](C)N2C[C@H]([C@@H](C)Oc3nc(Cl)cc4nc(C)n(C)c34)CC2=O)cc1 -US20130178540A1,2,CCCCCCCCN.CS(=O)CCC(NC(=O)OC(C)(C)C)C(=O)O>>CCCCCCCCNC(=O)C(CCS(C)=O)NC(=O)OC(C)(C)C -US07728144B2,2,CNCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1.COC(=O)c1ccc(C(=O)O)c(OC)c1>>COC(=O)c1ccc(C(=O)N(C)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(OC)c1 -US20080269268A1,1,Cn1ccc2c(N)ccnc21.O=[N+]([O-])c1ccc(I)c(F)c1>>Cn1ccc2c(Nc3ccc([N+](=O)[O-])cc3F)ccnc21 -US20120101136A1,1,CCOC(=O)CCCBr.CCc1cccc(O)c1>>CCOC(=O)CCCOc1cccc(CC)c1 -US20100160255A1,3,CC(C)(C)OC(=O)Nc1sc(Br)cc1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1.N#Cc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)Nc1sc(-c2ccc(C#N)cc2)cc1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 -US20130253197A1,2,CC(=O)O.Cc1c(-c2cnc3[nH]cc([C@H](C)c4c(OC(F)F)ccc(F)c4Cl)c3c2)cnn1C1CCNCC1>>CC(=O)N1CCC(n2ncc(-c3cnc4[nH]cc([C@H](C)c5c(OC(F)F)ccc(F)c5Cl)c4c3)c2C)CC1 -US07135475B2,2,CNc1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1.Cc1ccc(C(=O)O)cn1>>Cc1ccc(C(=O)N(C)c2ccc(Cc3nc4c([nH]3)c(=O)n(Cc3ccccc3F)c(=O)n4CC3CC3)cc2)cn1 -US08163793B2,1,CC(C)(C)N1CCNCC1.Cc1cc(N2C[C@H](S(=O)(=O)c3ccc(F)cc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)n(CCc2ccccc2)n1>>Cc1cc(N2C[C@H](S(=O)(=O)c3ccc(N4CCN(C(C)(C)C)CC4)cc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)n(CCc2ccccc2)n1 -US20100210642A1,3,C#Cc1cnn2c(C(F)(F)F)cc(-c3cccc(C(F)(F)F)c3)nc12.CC(C)(CO)NS(=O)(=O)c1cccc(Br)c1>>CC(C)(CO)NS(=O)(=O)c1cccc(C#Cc2cnn3c(C(F)(F)F)cc(-c4cccc(C(F)(F)F)c4)nc23)c1 -US20100210697A1,2,CC(=O)Nc1nc(CCc2ccc(CC(=O)O)cc2)cs1.NN>>CC(=O)Nc1nc(CCc2ccc(CC(=O)NN)cc2)cs1 -US06509359B1,6,CCC(CC)Nc1cc(C(=O)OC)ccc1N1C(=O)CCC1(CO)CO>>CCC(CC)Nc1cc(C(=O)O)ccc1N1C(=O)CCC1(CO)CO -US20150203515A1,1,CC(C)(C)[C@@H]1CC[C@@H](OS(C)(=O)=O)CC1.Oc1ccc2cc(Br)ccc2c1>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(Br)ccc3c2)CC1 -US20030055057A1,1,COC(=O)CCCCCOc1ccc2nc(-c3ccc(OC)cc3)n(CCC=O)c2c1.c1ccc(N2CCNCC2)cc1>>COC(=O)CCCCCOc1ccc2nc(-c3ccc(OC)cc3)n(CCCN3CCN(c4ccccc4)CC3)c2c1 -US06271395B1,2,CNC1c2ccccc2CC1N1CCCC1.O=C(O)Cc1ccc(Cl)c(Cl)c1>>CN(C(=O)Cc1ccc(Cl)c(Cl)c1)C1c2ccccc2CC1N1CCCC1 -US04016148,6,C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)NOP(C)(=O)O>>C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)NOP(C)(=O)O -US20040259912A1,1,CC(C)(C)CI.CCC(=O)c1cc([N+](=O)[O-])ccc1O>>CCC(=O)c1cc([N+](=O)[O-])ccc1OCC(C)(C)C -US06894061B2,6,CCC1c2c(C)cccc2-c2ccccc2N1S(=O)(=O)c1ccc(OC)cc1>>CCC1c2c(C)cccc2-c2ccccc2N1S(=O)(=O)c1ccc(O)cc1 -US20100056515A1,9,COC(=O)c1ccc(Cl)c2[nH]c(=O)n(C)c12.[NH4+]>>Cn1c(=O)[nH]c2c(Cl)ccc(C(N)=O)c21 -USRE045183E1,7,C[C@@H]1CC[C@@H](N(C(=O)Nc2ncc(C=O)s2)C2CCCCC2)CC1>>C[C@@H]1CC[C@@H](N(C(=O)Nc2ncc(CO)s2)C2CCCCC2)CC1 -US05591762,6,CCCCc1nc2ccc(-c3cn4ccccc4n3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2ccc(-c3cn4ccccc4n3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US08536179B2,6,COC(=O)c1ccc(C)c2c1ccn2C(C)C>>Cc1ccc(C(=O)O)c2ccn(C(C)C)c12 -US20080076774A1,6,CCN(CC)CCOc1cc(Cl)cc(N2CCN(C(=O)OC(C)(C)C)CC2)c1>>CCN(CC)CCOc1cc(Cl)cc(N2CCNCC2)c1 -US20040063733A1,6,COc1cc2c(Nc3cccc4c(Cl)c[nH]c34)ncnc2cc1OCC(CN1CCOCC1)OC(C)=O>>COc1cc2c(Nc3cccc4c(Cl)c[nH]c34)ncnc2cc1OCC(O)CN1CCOCC1 -US09006257B2,1,CC(C)(C)N.Cc1nc(Cl)c2cccc([N+](=O)[O-])c2n1>>Cc1nc(NC(C)(C)C)c2cccc([N+](=O)[O-])c2n1 -US04340758,7,Cc1cc(C(C)(C)C)cc(C)c1[N+](=O)[O-]>>Cc1cc(C(C)(C)C)cc(C)c1N -US20140135316A1,2,COC(=O)CC(=O)Cl.O=[N+]([O-])c1ccccc1NCc1ccccc1>>COC(=O)CC(=O)N(Cc1ccccc1)c1ccccc1[N+](=O)[O-] -US08354444B2,6,COC(=O)c1cc2cc(NC(=O)[C@@H]3N[C@@H](CC(C)(C)C)[C@](C#N)(c4ccc(Cl)cc4F)[C@H]3c3cccc(Cl)c3F)ccc2o1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc3oc(C(=O)O)cc3c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F -US20050267120A1,1,CC1CCNCC1.O=c1cc(CBr)oc2ccc(Br)cc12>>CC1CCN(Cc2cc(=O)c3cc(Br)ccc3o2)CC1 -US08455521B2,6,CN(C[C@H](CC1CCC(O[Si](C)(C)C(C)(C)C)CC1)NC(=O)OC(C)(C)C)C(=O)OCC[Si](C)(C)C>>CN(C[C@@H](N)CC1CCC(O[Si](C)(C)C(C)(C)C)CC1)C(=O)OCC[Si](C)(C)C -US20140135336A1,1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1cc(Cl)c(Cl)nn1>>CC(C)(C)OC(=O)N1CCC(Nc2cc(Cl)nnc2Cl)CC1 -US09120776B2,2,CCOC(=O)CCCN.N#Cc1ccc(C(=O)O)cc1>>CCOC(=O)CCCNC(=O)c1ccc(C#N)cc1 -US20150057279A1,2,CCN(CCN)c1cc(C)ccn1.O=C(O)/C=C/C(F)(F)F>>CCN(CCNC(=O)/C=C/C(F)(F)F)c1cc(C)ccn1 -US05753679,7,CCOC(=O)C1CCN(C(=O)c2ccccc2)CC1>>O=C(c1ccccc1)N1CCC(CO)CC1 -US08394858B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=S(=O)(NCc1ccccc1)c1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)N(Cc1ccccc1)S(=O)(=O)c1ccc(C(F)(F)F)cc1 -US20100076026A1,2,COC(=O)c1ccc(N=C=O)c(Cl)c1.Clc1ccc(-n2nc3ccccc3c2Nc2ccccc2)cc1>>COC(=O)c1ccc(NC(=O)N(c2ccccc2)c2c3ccccc3nn2-c2ccc(Cl)cc2)c(Cl)c1 -US07851032B2,3,CCOc1ccc(B(O)O)c(F)c1F.Oc1ccc(Br)c(F)c1F>>CCOc1ccc(-c2ccc(O)c(F)c2F)c(F)c1F -US05317024,2,CC(C)(C)OC(=O)N1CCC(CCO)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(CCOS(C)(=O)=O)CC1 -US20130065876A1,2,CS(=O)(=O)Cl.O=C(NN1CCNCC1)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1>>CS(=O)(=O)N1CCN(NC(=O)c2cnc(OCC(F)(F)F)c(-c3ccc(Cl)cc3)c2)CC1 -US20090163471A1,1,BrCc1ccccc1.N#Cc1ccc(C(=O)O)cc1Br>>N#Cc1ccc(C(=O)OCc2ccccc2)cc1Br -US20020016337A1,2,CCC(=O)Cl.c1ccc(CN2CCCC(Nc3ccccc3)C2)cc1>>CCC(=O)N(c1ccccc1)C1CCCN(Cc2ccccc2)C1 -US20120328691A1,1,O=[N+]([O-])c1ccccc1F.c1cn(C2CCNCC2)cn1>>O=[N+]([O-])c1ccccc1N1CCC(n2ccnc2)CC1 -US20080306120A1,1,C1CCNC1.CCn1cc(-c2ccnc3c2cc(-c2ccc(C=O)cc2)n3S(=O)(=O)c2ccccc2)c(-c2ccc([N+](=O)[O-])cc2)n1>>CCn1cc(-c2ccnc3c2cc(-c2ccc(CN4CCCC4)cc2)n3S(=O)(=O)c2ccccc2)c(-c2ccc([N+](=O)[O-])cc2)n1 -US08349824B2,2,C1CNC1.Cn1ncc(C(=O)O)c1C(=O)Nc1ccn2nc(-c3cccc(F)c3)nc2c1>>Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccn2nc(-c3cccc(F)c3)nc2c1 -US20050234238A1,1,Brc1ccc(Br)nc1.Fc1ccc(CS)cc1>>Fc1ccc(CSc2ccc(Br)cn2)cc1 -US20130237709A1,6,COC(=O)C(C)(C)c1ccc(C(CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)(OC)OC)cc1>>COC(=O)C(C)(C)c1ccc(C(=O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 -US20120202856A1,7,Cc1cc(-c2ccccc2C(F)(F)F)cc([N+](=O)[O-])c1N>>Cc1cc(-c2ccccc2C(F)(F)F)cc(N)c1N -US04711898,2,O=C(O)c1cccc2c1N=C(c1ccccc1Cl)CC2=O.OCCO>>O=C1CC(c2ccccc2Cl)=Nc2c1cccc2C(=O)OCCO -US20030171584A1,9,CC(=O)CC(C)(C)O.NO>>CC(CC(C)(C)O)=NO -US20050159474A1,6,CC(C)(C)OC(=O)CC[C@H](N)C(=O)Nc1cccc(COc2ccc3[nH]c(C(N)=O)cc3c2)c1>>NC(=O)c1cc2cc(OCc3cccc(NC(=O)[C@@H](N)CCC(=O)O)c3)ccc2[nH]1 -US05817678,2,Cc1ccc(S(=O)(=O)Cl)cc1.OC[C@H]1CCCN(CC(c2ccccc2)c2ccccc2)C1>>Cc1ccc(S(=O)(=O)OC[C@H]2CCCN(CC(c3ccccc3)c3ccccc3)C2)cc1 -US20080269487A1,2,CC(C)(C)OC(=O)N1CC[C@H](O)C1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CC(C)(C)OC(=O)N1CC[C@H](OS(=O)(=O)c2ccc([N+](=O)[O-])cc2)C1 -US20060189650A1,9,CCOC(=O)c1ccc(S(=O)(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)cc1.N>>CC(C)(C)OC(=O)N1CCC(CCS(=O)(=O)c2ccc(C(N)=O)cc2)CC1 -US20050288273A1,3,C#CCCC(=O)OC.O=[N+]([O-])c1cc(F)cc(I)c1>>COC(=O)CCC#Cc1cc(F)cc([N+](=O)[O-])c1 -US06462081B1,8,O=C1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@H]2CO)O1>>O=C[C@@H]1[C@H](OC2CCCCO2)C[C@@H]2OC(=O)C[C@@H]21 -US05214206,2,CC(C)c1cccc(C(C)C)c1NC(=O)NS(=O)(=O)Cl.NC(c1ccccc1)c1ccccc1>>CC(C)c1cccc(C(C)C)c1NC(=O)NS(=O)(=O)NC(c1ccccc1)c1ccccc1 -US04523030,6,COC(=O)C1=Cc2cc(C(=O)c3ccccc3)c(O)cc21>>O=C(O)C1=Cc2cc(C(=O)c3ccccc3)c(O)cc21 -US20130029980A1,1,CC(C)OC(COS(C)(=O)=O)Cc1ccc(Cl)cc1.[N-]=[N+]=[N-]>>CC(C)OC(CN=[N+]=[N-])Cc1ccc(Cl)cc1 -US20090181942A1,1,C=CC(=O)OC(C)(C)C.O=C(OCc1ccccc1)N1CCC(O)CC1>>CC(C)(C)OC(=O)CCOC1CCN(C(=O)OCc2ccccc2)CC1 -US20030083335A1,1,CCOC(=O)Cc1cc(Cl)ccc1O.C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)CCl>>CCOC(=O)Cc1cc(Cl)ccc1OCC(=O)N1CC(C)N(Cc2ccc(F)cc2)CC1C -US04689345,8,CCC(O)CCC1CCC2CC(=O)CC12>>CCC(=O)CCC1CCC2CC(=O)CC12 -US08735584B2,1,CC(C)c1ccc(N)cc1.O=c1[nH]c2ncccc2c2cc(Cl)ccc12>>CC(C)c1ccc(Nc2ccc3c(=O)[nH]c4ncccc4c3c2)cc1 -US05418236,3,Cn1cccc1C(=O)c1ccc([N+](=O)[O-])cc1.O=C(Cl)CCl>>Cn1cc(C(=O)CCl)cc1C(=O)c1ccc([N+](=O)[O-])cc1 -US08987248B2,7,Cc1cccc(-c2cncc(NC(=O)c3ccccc3)c2)c1C>>Cc1cccc(C2CNCC(NC(=O)c3ccccc3)C2)c1C -US05350762,7,CCOC(=O)C1Cc2c(n(C)c3ccc(OC)cc23)C1>>COc1ccc2c(c1)c1c(n2C)CC(CO)C1 -US20070244125A1,2,CC(C)n1c(C(=O)O)cc2cc(C(=O)N3CCCN(C(=O)OC(C)(C)C)CC3)ccc21.FC1(F)CCNCC1>>CC(C)n1c(C(=O)N2CCC(F)(F)CC2)cc2cc(C(=O)N3CCCN(C(=O)OC(C)(C)C)CC3)ccc21 -US20150202332A1,1,COC(=O)c1ccc(O)cc1.FCCBr>>COC(=O)c1ccc(OCCF)cc1 -US04250085,6,CCC[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC)C(=O)N[C@@H](C)P(=O)(O)O>>CCC[C@H](N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](C)P(=O)(O)O -US20140378446A1,1,COC(=O)/C=C/CBr.N[C@H]1CCOC1>>COC(=O)/C=C/CN[C@H]1CCOC1 -US20120184531A1,6,COc1ccc(S(=O)(=O)c2ccc3oc4c(c3c2)CN(C(=O)OC(C)(C)C)CC4)cc1>>COc1ccc(S(=O)(=O)c2ccc3oc4c(c3c2)CNCC4)cc1 -US08338605B2,1,Cc1ccc(Cl)c([N+](=O)[O-])c1.Nc1cccc(S)c1>>Cc1ccc(Sc2cccc(N)c2)c([N+](=O)[O-])c1 -US20070265298A1,7,COC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1C>>COC(=O)c1ccc(-c2ccc(N)cc2)cc1C -US20090004185A1,3,CC(C)(C)/C=C/B(O)O.CN(C)c1nc(NCc2ccc(NC(=O)C3CCN(Cc4ccccc4)CC3)cc2)c2ccc(I)cc2n1>>CN(C)c1nc(NCc2ccc(NC(=O)C3CCN(Cc4ccccc4)CC3)cc2)c2ccc(/C=C/C(C)(C)C)cc2n1 -US20010044426A1,7,COC(=O)C1Cc2ccc([N+](=O)[O-])cc21>>COC(=O)C1Cc2ccc(N)cc21 -US20150087585A1,2,C1=CCNC1.O=C(O)[C@@H]1CCCN(c2ccc3nc(-c4cccc(C5CC5)n4)[nH]c3n2)C1>>O=C([C@@H]1CCCN(c2ccc3nc(-c4cccc(C5CC5)n4)[nH]c3n2)C1)N1CC=CC1 -US07462634B2,2,CC(C)(C)[Si](C)(C)OCc1cccc(N)n1.N#Cc1ccc(-c2ccc(S(=O)(=O)Cl)cc2)cc1>>CC(C)(C)[Si](C)(C)OCc1cccc(NS(=O)(=O)c2ccc(-c3ccc(C#N)cc3)cc2)n1 -US07507841B2,3,CN(C)c1ccc(B(O)O)cn1.Cc1c(Br)c2c(c(C)c1NC(=O)CC(C)(C)C)C(c1ccc(C(C)C)cc1)CO2>>Cc1c(NC(=O)CC(C)(C)C)c(C)c2c(c1-c1ccc(N(C)C)nc1)OCC2c1ccc(C(C)C)cc1 -US20050014786A1,2,N#Cc1ccc2c(c1)C[C@H](N)CN2.O=S(=O)(Cl)c1ccccc1>>N#Cc1ccc2c(c1)C[C@H](NS(=O)(=O)c1ccccc1)CN2 -US20150175563A1,3,CC1(C)OB(C2=CCOCC2)OC1(C)C.CCOC(=O)c1sc(Br)c(C#N)c1Br>>CCOC(=O)c1sc(C2=CCOCC2)c(C#N)c1Br -US08536159B2,8,CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Sc2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12.O=S([O-])OO>>CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2S(=O)c2ccccc2)N2C1=N[C@@H]1CCC[C@@H]12 -US20050130984A1,7,O=[N+]([O-])c1ccc2c(c1)S(=O)(=O)CCO2>>Nc1ccc2c(c1)S(=O)(=O)CCO2 -US06417222B1,3,COc1ccc(Br)cc1C=O.OB(O)c1ccsc1>>COc1ccc(-c2ccsc2)cc1C=O -US08101610B2,2,Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(N)c1.O=C(O)c1cccc(F)c1>>Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(NC(=O)c2cccc(F)c2)c1 -US20100160309A1,3,C#Cc1ccccc1.CC(Nc1nc2cc[nH]c(=O)c2c2cc(Br)ccc12)C(C)(C)C>>CC(Nc1nc2cc[nH]c(=O)c2c2cc(C#Cc3ccccc3)ccc12)C(C)(C)C -US08436023B2,1,CCn1nc(NCC(=O)NC2CNC2)c2cc(C(F)(F)F)ccc21.Cc1ncc(C2(O)CCC(=O)CC2)s1>>CCn1nc(NCC(=O)NC2CN(C3CCC(O)(c4cnc(C)s4)CC3)C2)c2cc(C(F)(F)F)ccc21 -US20150250792A1,6,CCOC(=O)C(O)CCNC(=O)C1O[C@H](c2ccc(OC)cc2)OCC1(C)C>>COc1ccc([C@@H]2OCC(C)(C)C(C(=O)NCCC(O)C(=O)O)O2)cc1 -US04259495,9,Clc1nc(Cl)c(Cl)c(Cl)c1Cl>>Clc1cc(Cl)c(Cl)nc1Cl -US07022721B1,2,CN1CCN(CCCN)CC1.S=C=NC1CCCCC1>>CN1CCN(CCCNC(=S)NC2CCCCC2)CC1 -US20080188528A1,2,COC(=O)C[C@@H](N)CCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CCC(C)(C)O2.O=C(O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O>>COC(=O)C[C@H](CCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CCC(C)(C)O2)NC(=O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O -US20040138230A1,1,CI.O=c1[nH]c2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc2c2c1CCC2>>Cn1c(=O)c2c(c3cc(CCN4CCN(c5nsc6ccccc56)CC4)ccc31)CCC2 -US07618970B2,6,CC(C)[C@]1(C(=O)N2CCN(c3cccc(C(F)(F)F)n3)CC2)CC[C@@H](NC(=O)OC(C)(C)C)C1>>CC(C)[C@]1(C(=O)N2CCN(c3cccc(C(F)(F)F)n3)CC2)CC[C@@H](N)C1 -US04962193,7,O=c1ccn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]1>>O=c1ccn([C@H]2CC[C@@H](CO)O2)c(=O)[nH]1 -US07816395B2,2,CCNC[C@H](CC(=O)OC(C)(C)C)Nc1ccc(C#N)c(Cl)c1>>CCN1C[C@@H](Nc2ccc(C#N)c(Cl)c2)CC1=O -US20120225854A1,1,CNC[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1.Cn1cnc(C=O)c1>>CN(Cc1cn(C)cn1)C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1 -US06962935B2,4,CCOC(=O)C(Br)C(=O)c1cccc(C#N)c1.NC(N)=S>>CCOC(=O)c1sc(N)nc1-c1cccc(C#N)c1 -US04183852,1,C1=COCCC1.COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC5CCCCO5)CC[C@]4(C)[C@H]3CC[C@]12C -US05260177,2,Nc1ncc([N+](=O)[O-])cc1Br.O=C(Cl)c1ccccc1>>O=C(Nc1ncc([N+](=O)[O-])cc1Br)c1ccccc1 -US08022206B2,2,C[C@@H](Oc1c(N)ncc2c(C3=CCNCC3)coc12)c1c(Cl)ccc(F)c1Cl.O=C=Nc1ccccc1Cl>>C[C@@H](Oc1c(N)ncc2c(C3=CCN(C(=O)Nc4ccccc4Cl)CC3)coc12)c1c(Cl)ccc(F)c1Cl -US20040138199A1,6,CC(C)(C)OC(=O)N1CCOc2ccc(C=O)cc21>>O=Cc1ccc2c(c1)NCCO2 -US20130096122A1,3,O=C1CCc2cc(Br)c(OCc3ccc(C(=O)O)cc3)cc2N1.OB(O)c1ccc(Cl)cc1>>O=C1CCc2cc(-c3ccc(Cl)cc3)c(OCc3ccc(C(=O)O)cc3)cc2N1 -US20050209324A1,9,COC(=O)c1cc(F)cc([N+](=O)[O-])c1CBr.[N-]=[N+]=[N-]>>COC(=O)c1cc(F)cc([N+](=O)[O-])c1CN=[N+]=[N-] -US20050283006A1,7,N#CCCCc1c[nH]c(-c2ccc(F)cc2)c1-c1ccncc1>>NCCCCc1c[nH]c(-c2ccc(F)cc2)c1-c1ccncc1 -US07572809B2,2,CNCC1CCCCO1.Cc1cc(Nc2cc3cc(C(=O)O)ccc3c(OC(C)C)n2)n[nH]1>>Cc1cc(Nc2cc3cc(C(=O)N(C)CC4CCCCO4)ccc3c(OC(C)C)n2)n[nH]1 -US08410107B2,2,Nc1cnc(OCC2CC2)c(-c2ccc(Cl)cc2)c1.O=C(O)c1ccncc1>>O=C(Nc1cnc(OCC2CC2)c(-c2ccc(Cl)cc2)c1)c1ccncc1 -US20060178384A1,7,COc1ccc2c(c1)CCn1c-2cc(Nc2cccc([N+](=O)[O-])c2)nc1=O>>COc1ccc2c(c1)CCn1c-2cc(Nc2cccc(N)c2)nc1=O -US07695980B2,6,COC(=O)c1c2ccccc2nc2sccc12>>O=C(O)c1c2ccccc2nc2sccc12 -US20060084690A1,2,CCOP(=O)(Cc1ccc(N)cc1)OCC.O=C(O)CCc1cnoc1-c1ccc(F)cc1>>CCOP(=O)(Cc1ccc(NC(=O)CCc2cnoc2-c2ccc(F)cc2)cc1)OCC -US04154742,1,C=CCBr.Oc1cccc(Cl)c1Cl>>C=CCOc1cccc(Cl)c1Cl -US20150080373A1,1,COC(=O)CBr.O=C1CSc2ccc(C(=O)NC3CCN(CCOc4cnc5ccc(O)cc5n4)CC3)cc2N1>>COC(=O)COc1ccc2ncc(OCCN3CCC(NC(=O)c4ccc5c(c4)NC(=O)CS5)CC3)nc2c1 -US20150274720A1,2,N#Cc1ccnc(N)c1.O=S(=O)(Cl)c1ccccc1>>N#Cc1ccnc(NS(=O)(=O)c2ccccc2)c1 -US04585768,1,CN(CCCl)Cc1ccccc1.COc1ccc([C@@H]2Sc3cc(Cl)ccc3NC(=O)[C@@H]2OC(C)=O)cc1>>COc1ccc([C@@H]2Sc3cc(Cl)ccc3N(CCN(C)Cc3ccccc3)C(=O)[C@@H]2OC(C)=O)cc1 -US20100298290A1,3,CC1(C)CCc2ncnc(N3CCOc4ccc(B(O)O)cc4C3)c2C1.CNc1ncc(Br)cc1NS(C)(=O)=O>>CNc1ncc(-c2ccc3c(c2)CN(c2ncnc4c2CC(C)(C)CC4)CCO3)cc1NS(C)(=O)=O -US05036086,2,CC(=O)OCC(=O)Cl.Nc1nc2c(Cl)cccc2s1>>CC(=O)OCC(=O)Nc1nc2c(Cl)cccc2s1 -US20050171131A1,1,CCc1nc(N)nc(N)c1-c1ccc2[nH]cc(CC)c2c1.CS(=O)(=O)c1ccc(CBr)cc1>>CCc1nc(N)nc(N)c1-c1ccc2c(c1)c(CC)cn2Cc1ccc(S(C)(=O)=O)cc1 -US04711890,2,CC1CCCNC1.CCOC(=O)c1nc(-c2ccccc2)nc2ccccc12>>CC1CCCN(C(=O)c2nc(-c3ccccc3)nc3ccccc23)C1 -US08003662B2,3,Nc1ccc(Oc2ccnc3cc(I)sc23)c(F)c1.OB(O)c1ccccc1>>Nc1ccc(Oc2ccnc3cc(-c4ccccc4)sc23)c(F)c1 -US04600719,7,O=C(C1CC1)N1CCC(c2cc3ccccc3o2)CC1>>c1ccc2oc(C3CCN(CC4CC4)CC3)cc2c1 -US20140005175A1,2,CC(C)(C(=O)O)c1ccc(S(=O)(=O)/C=C/C#N)cc1.COc1cccc(CN)c1>>COc1cccc(CNC(=O)C(C)(C)c2ccc(S(=O)(=O)/C=C/C#N)cc2)c1 -US07615568B2,6,COc1ccc(CO[C@@H](CNC(=O)OC(C)(C)C)CO[Si](C(C)C)(C(C)C)C(C)C)cc1OC>>COc1ccc(CO[C@H](CO)CNC(=O)OC(C)(C)C)cc1OC -US04760074,1,Clc1ncccn1.NCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)CC1>>Fc1ccc(Cn2c(NC3CCN(CCNc4ncccn4)CC3)nc3ccccc32)cc1 -US20100311966A1,1,CCc1[nH]c(C(=O)N[C@H]2CCNC[C@H]2OC)nc1Cl.COC(=O)c1ccc(F)nc1>>CCc1[nH]c(C(=O)N[C@H]2CCN(c3ccc(C(=O)OC)cn3)C[C@H]2OC)nc1Cl -US20130267493A1,6,CCOC(=O)c1n[nH]c2cc(Cl)c(-c3ccc(N4CCOCC4)cc3)cc12>>O=C(O)c1n[nH]c2cc(Cl)c(-c3ccc(N4CCOCC4)cc3)cc12 -US20120041012A1,1,CCOc1cc(CCl)cc(OCC)c1-c1ccc(F)cc1.COC(=O)CN1CC2(CCNCC2)CC1=O>>CCOc1cc(CN2CCC3(CC2)CC(=O)N(CC(=O)OC)C3)cc(OCC)c1-c1ccc(F)cc1 -US20090312327A1,2,CN(C(=O)Cc1ccc(F)cc1)C1CNCC1c1ccc(Cl)c(Cl)c1.Cc1noc(-c2ccc(C(=O)O)cc2)n1>>Cc1noc(-c2ccc(C(=O)N3CC(c4ccc(Cl)c(Cl)c4)C(N(C)C(=O)Cc4ccc(F)cc4)C3)cc2)n1 -US06706751B2,2,C=CCN(C)CCCCCc1ccc2c(c1)CCN2.O=C(Cl)Oc1ccc(Cl)cc1>>C=CCN(C)CCCCCc1ccc2c(c1)CCN2C(=O)Oc1ccc(Cl)cc1 -US20110182850A1,6,C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)NS(=O)(=O)C1(CCC)CC1>>C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)C1(CCC)CC1 -US20150259343A1,7,O=C1CC(C2CCOC2)c2ccccc2N1>>c1ccc2c(c1)NCCC2C1CCOC1 -US20150031674A1,2,CC(C)(C)OC(=O)N1CCC2(CC(O)CO2)C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC2COC3(CCN(C(=O)OC(C)(C)C)C3)C2)cc1 -US20070232607A1,2,C1CCNC1.COC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>C[C@@H](Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)N1CCCC1 -US04233446,1,CCOC(=O)c1c(Cl)c2cnc(-c3ccccc3)nc2n(CCOC)c1=O.COCCN>>CCOC(=O)c1c(NCCOC)c2cnc(-c3ccccc3)nc2n(CCOC)c1=O -US20050256107A1,1,CC1CCC(C)N1.O=[N+]([O-])c1ccc(F)cc1>>CC1CCC(C)N1c1ccc([N+](=O)[O-])cc1 -US06596738B1,3,CCOC(=O)CP(=O)(OCC)OCC.Cn1cc(C=O)c2cc(OCc3ccccc3)ccc21>>CCOC(=O)C=Cc1cn(C)c2ccc(OCc3ccccc3)cc12 -US09156829B2,2,N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1.O=C(O)c1cc(Cl)ccc1-n1cccn1>>O=C(N[C@H]1CCC[C@@H]1Nc1cnc(C(F)(F)F)cn1)c1cc(Cl)ccc1-n1cccn1 -US20150018322A1,2,CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)CCC1C2CC[C@@]2(C)C1CC[C@@H]2OC(=O)CO.NS(=O)(=O)c1cccc(C(=O)Cl)c1>>CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)CCC1C2CC[C@@]2(C)C1CC[C@@H]2OC(=O)COC(=O)c1cccc(S(N)(=O)=O)c1 -US20100113803A1,1,CI.COC(=O)C1NC(=O)CC1c1c(OC)cc(OC)cc1OC>>COC(=O)C1C(c2c(OC)cc(OC)cc2OC)CC(=O)N1C -US20090196912A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cccc(CNc2cncc(Br)c2)c1>>COc1cccc(CN(C(=O)OC(C)(C)C)c2cncc(Br)c2)c1 -US20070185152A1,7,CC(C)(C)OC(=O)N[C@H](CC(=O)O)Cc1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)N[C@H](CCO)Cc1ccc(C(F)(F)F)cc1 -US08921402B2,4,CC(=O)CCC(C)=O.Cc1nn(-c2ccc(O)cc2F)c(N)c1C#N>>Cc1nn(-c2ccc(O)cc2F)c(-n2c(C)ccc2C)c1C#N -US20060116366A1,3,CC(C)(C)C1CCC(=O)CC1.CCOP(=O)(CC#N)OCC>>CC(C)(C)C1CCC(=CC#N)CC1 -US20100184978A1,3,C[SiH](C)c1cc(C(C)(C)C)cnc1Br.[Zn+]c1ccccn1>>C[SiH](C)c1cc(C(C)(C)C)cnc1-c1ccccn1 -US07563815B2,2,Cn1c(N(Cc2ccc(C(=O)O)cc2)C2CCC(C(C)(C)C)CC2)nc2cc(O)ccc21.Nc1nnn[nH]1>>Cn1c(N(Cc2ccc(C(=O)Nc3nnn[nH]3)cc2)C2CCC(C(C)(C)C)CC2)nc2cc(O)ccc21 -US20130289033A1,3,Cc1ccc(B(O)O)cc1C.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1>>Cc1ccc(-c2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)cc1C -US20050250836A1,1,COCCBr.O=Cc1ccc[nH]1>>COCCn1cccc1C=O -US20110313151A1,2,CC#CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1>>CC#CC(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1 -US20120022075A1,6,CNS(=O)(=O)c1ccc(Oc2cc(O[C@@H](C)COC)cc(-c3ccc(C4=NC[C@H](C)O4)[nH]3)c2)cn1>>CNS(=O)(=O)c1ccc(Oc2cc(O[C@@H](C)CO)cc(-c3ccc(C4=NC[C@H](C)O4)[nH]3)c2)cn1 -US08969583B2,2,Cc1ccc(N=C=O)cc1.NC(=O)c1c(-c2ccc(N)cc2)nsc1NC(=O)N1CCCC1=O>>Cc1ccc(NC(=O)Nc2ccc(-c3nsc(NC(=O)N4CCCC4=O)c3C(N)=O)cc2)cc1 -US20130150326A1,1,CC(C)n1cc(Br)cn1.CCOC(=O)c1cc(F)cc(Sc2c(C)[nH]c3c(F)c(Cl)ccc23)c1>>CCOC(=O)c1cc(F)cc(Sc2c(C)n(-c3cnn(C(C)C)c3)c3c(F)c(Cl)ccc23)c1 -US06562989B2,1,C1COCCN1.N#Cc1ccc(Cl)cc1>>N#Cc1ccc(N2CCOCC2)cc1 -US20090298836A1,2,CC(C)(C)OC(=O)N[C@H](c1ccc(C(F)(F)F)cc1)[C@@H](O)CO[Si](C)(C)C(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@H](c1ccc(C(F)(F)F)cc1)[C@H](CO[Si](C)(C)C(C)(C)C)OS(C)(=O)=O -US05348944,1,CCOC(=O)C(=O)Cc1c[nH]c2ccccc12.C[C@H](N)C(=O)N1C2CCCCC2C[C@H]1C(=O)O>>CCOC(=O)C(Cc1c[nH]c2ccccc12)N[C@@H](C)C(=O)N1C2CCCCC2C[C@H]1C(=O)O -US20070066675A1,3,CC1(C)CC(=O)c2ccc(OS(=O)(=O)C(F)(F)F)cc21.OB(O)c1ccccc1>>CC1(C)CC(=O)c2ccc(-c3ccccc3)cc21 -US20060116410A1,2,CC(=O)Cl.CNC(=O)COc1cc(C#N)ccc1CNC(=O)c1cc(N)c(F)c(Cl)c1>>CNC(=O)COc1cc(C#N)ccc1CNC(=O)c1cc(Cl)c(F)c(NC(C)=O)c1 -US20060178375A1,3,Brc1cnc(OC2CCN(C3CCCC3)CC2)nc1.O=C(c1ccc(B(O)O)cc1)N1CCCC1>>O=C(c1ccc(-c2cnc(OC3CCN(C4CCCC4)CC3)nc2)cc1)N1CCCC1 -US04721784,7,CC1CC(=O)NN=C1c1ccc2c(c1)NC(=O)CO2>>CC1CC(=O)NN=C1c1ccc2c(c1)NCCO2 -US06228866B1,7,N#CCC1(CC#N)CC1>>N#CCC1(CCN)CC1 -US20120270865A2,2,CCOC(=O)CCNC.Cc1c(C(Nc2ccc(C(=O)O)cc2)C2CCCCC2)oc2ccc(Cl)nc12>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(Cl)nc3c2C)C2CCCCC2)cc1 -US06284796B1,3,C=Cc1ccccc1.N#Cc1ccc2cc(OS(=O)(=O)C(F)(F)F)ccc2c1>>N#Cc1ccc2cc(/C=C/c3ccccc3)ccc2c1 -US07645781B2,4,CC(=O)CCC(C)=O.C[C@@H]1Cc2cc(N)ccc2N1>>Cc1ccc(C)n1-c1ccc2c(c1)C[C@@H](C)N2 -US05972937,6,CCOC(=O)c1ccc(NC(=O)N2CCc3cc(SC)c(C(F)(F)F)cc32)cc1>>CSc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(C(=O)O)cc1)CC2 -US04228284,1,N#Cc1cccc2c1CC(=O)c1cc(F)ccc1S2.NN>>N#Cc1cccc2c1CC(=NN)c1cc(F)ccc1S2 -US05814646,1,Brc1ccc2ccccc2c1.O=[N+]([O-])c1ccc(S)cc1>>O=[N+]([O-])c1ccc(Sc2ccc3ccccc3c2)cc1 -US20060116410A1,2,CNC(=O)COc1cc(C#N)ccc1CN.O=C(O)c1cncc(Cl)c1>>CNC(=O)COc1cc(C#N)ccc1CNC(=O)c1cncc(Cl)c1 -US20090325952A1,2,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(N)c1.O=C(Cl)CCCCCCCBr>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(NC(=O)CCCCCCCBr)c1 -US07317014B2,9,FC(F)(F)c1nc(Cl)c(-c2ccccc2)c(-c2ccccc2)n1.[N-]=[N+]=[N-]>>[N-]=[N+]=Nc1nc(C(F)(F)F)nc(-c2ccccc2)c1-c1ccccc1 -US20070054902A1,3,CN(C)C=O.COCOCc1cc(-c2ccc(C(F)(F)F)cc2)on1>>COCOCc1noc(-c2ccc(C(F)(F)F)cc2)c1C=O -US20070082907A1,1,O=C(O)c1ccc(C(F)(F)F)cc1F.Oc1ccccc1>>O=C(O)c1ccc(C(F)(F)F)cc1Oc1ccccc1 -US20110065759A1,3,O=C(N[C@H]1CCCC[C@H]1O)c1cnc(OCC(F)(F)F)c(Br)c1.OB(O)c1ccc(Cl)c(Cl)c1>>O=C(N[C@H]1CCCC[C@H]1O)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)c(Cl)c2)c1 -US20090048307A1,4,Cc1cc(C)cc(C(=O)C(Br)c2ccnc(OCc3ccccc3)c2)c1.NC(N)=S>>Cc1cc(C)cc(-c2nc(N)sc2-c2ccnc(OCc3ccccc3)c2)c1 -US06602867B1,1,ClCCCBr.O=S(=O)(c1ccc2c(c1)CNCC2)N1CCOCC1>>O=S(=O)(c1ccc2c(c1)CN(CCCCl)CC2)N1CCOCC1 -US20100144760A1,3,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1ccc(C)nc1Br>>C=Cc1nc(C)ccc1C(=O)OC -US06809093B2,6,CC(C)(C)OC(=O)N1CCCCC1C(=O)N1CCC(C(=O)NC(CCCc2ccccc2)CCCc2ccccc2)CC1>>O=C(NC(CCCc1ccccc1)CCCc1ccccc1)C1CCN(C(=O)C2CCCCN2)CC1 -US06258827B1,7,CC(C(=O)c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1)N1CCC(O)(c2cc(Br)cc(Br)c2)CC1>>CC(C)[Si](Oc1ccc([C@@H](O)[C@@H](C)N2CCC(O)(c3cc(Br)cc(Br)c3)CC2)cc1)(C(C)C)C(C)C -US20100130737A1,6,CCOC(=O)c1cc2cc(-c3cccnc3)ccc2s1>>O=C(O)c1cc2cc(-c3cccnc3)ccc2s1 -US20140378432A1,7,Cn1cc(-c2cncc(-n3ncc4c5c(sc4c3=O)CCCC5)c2C=O)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O>>Cn1cc(-c2cncc(-n3ncc4c5c(sc4c3=O)CCCC5)c2CO)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O -US20090137587A1,1,C=O.CCN(CC)CCNc1ccc(-n2ccc(OCc3ccccc3)cc2=O)cc1>>CCN(CC)CCN(C)c1ccc(-n2ccc(OCc3ccccc3)cc2=O)cc1 -US04698355,2,N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1>>N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 -US20150210678A1,9,CC(C)c1ccc(Cl)cc1C=O.NO>>CC(C)c1ccc(Cl)cc1C=NO -US08173650B2,6,COCCN(Cc1ccccc1)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1>>COCCNc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1 -US07132457B2,7,O=C(O)CCc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(CCCO)ccc1Cl -US07897773B2,7,O=C(N1CCCc2ccccc21)N1C2C=C(c3cccnc3)CC1CC2>>O=C(N1CCCc2ccccc21)N1C2CCC1CC(c1cccnc1)C2 -US20110059941A1,1,CO.COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2nc3nc(Br)cnc3[nH]2)c1>>COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2nc3nc(OC)cnc3[nH]2)c1 -US20110130380A1,6,CC1(C)COC(CNc2nc(OCc3ccccc3)ccc2F)CO1>>CC1(C)COC(CNc2nc(O)ccc2F)CO1 -US20120142668A1,6,CC[C@@H](/C=C/C(=O)OC)NC(=O)OC(C)(C)C>>CC[C@H](N)/C=C/C(=O)OC -US06165942,1,C#CCBr.N#Cc1cc(F)c(-n2c(=O)cc(C(F)(F)F)n3ccnc23)cc1O>>C#CCOc1cc(-n2c(=O)cc(C(F)(F)F)n3ccnc23)c(F)cc1C#N -US05374772,1,CCCCCCCCCCCCCCCCCCBr.COC(=O)c1ccc(O)cc1O>>CCCCCCCCCCCCCCCCCCOc1ccc(C(=O)OC)c(O)c1 -US05889021,8,CCC(=O)c1cnc2c(OCCSC)cccc2c1Nc1ccccc1C.O=C(OO)c1cccc(Cl)c1>>CCC(=O)c1cnc2c(OCCS(C)=O)cccc2c1Nc1ccccc1C -US20040214832A1,7,COCCCNc1cc(OCc2ccccc2)ccc1C#N>>COCCCNc1cc(OCc2ccccc2)ccc1CN -US06448247B1,6,CC(C)(C)OC(=O)N1CCC2(CC1)c1ccccc1CS2=O>>O=S1Cc2ccccc2C12CCNCC2 -US08697696B2,2,CC1(N)COC1.Cc1nnn(-c2ccc(F)cc2)c1COc1cc(C(=O)O)n(C)n1>>Cc1nnn(-c2ccc(F)cc2)c1COc1cc(C(=O)NC2(C)COC2)n(C)n1 -US20130324531A1,2,CC(C)(C)OC(=O)CCO.COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F>>COc1cc(C(=O)OCCC(=O)OC(C)(C)C)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F -US20050165050A1,7,COc1ccc(F)cc1C1(CC(O)(C=Nc2cccc3ncccc23)C(F)(F)F)CC1>>COc1ccc(F)cc1C1(CC(O)(CNc2cccc3ncccc23)C(F)(F)F)CC1 -US20080027080A1,6,CC(=O)N[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CC[C@@H]1N1CC[C@H](NC(=O)OCc2ccccc2)C1=O>>CC(=O)N[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CC[C@@H]1N1CC[C@H](N)C1=O -US07915274B2,8,OC(Cc1ccccc1F)C1CCN(Cc2ccccc2)CC1>>O=C(Cc1ccccc1F)C1CCN(Cc2ccccc2)CC1 -US05077303,4,COC=C(C(=O)OC)c1ccccc1C=Cc1ccccc1.O=C(OO)c1cccc(Cl)c1>>COC=C(C(=O)OC)c1ccccc1[C@@H]1O[C@H]1c1ccccc1 -US20080280875A1,1,C=CCBr.COC(=O)c1cc(O)cc(O)c1>>C=CCOc1cc(O)cc(C(=O)OC)c1 -US20150218181A1,1,CI.CN(C)S(=O)(=O)c1ccc(N2C(=O)c3ccccc3C2=O)c(O)c1>>COc1cc(S(=O)(=O)N(C)C)ccc1N1C(=O)c2ccccc2C1=O -US08242145B2,1,CCOC(=O)Cc1cc(Cl)cc(Oc2ccc(Br)cc2CBr)c1.C[C@H]1NC(=O)O[C@H]1c1ccccc1>>CCOC(=O)Cc1cc(Cl)cc(Oc2ccc(Br)cc2CN2C(=O)O[C@@H](c3ccccc3)[C@H]2C)c1 -US07985759B2,1,N#C[C@@H]1CCCN1C(=O)CCl.NC12CC3CC(CC1C3)C2>>N#C[C@@H]1CCCN1C(=O)CNC12CC3CC(CC1C3)C2 -US20050143381A1,6,O=c1c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)cnn1Cc1ccccc1>>O=c1[nH]ncc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1 -US07893099B2,6,CCOC(=O)[C@@H]1CC(=O)C[C@H]1C(=O)OCC>>CCOC(=O)[C@@H]1CC(=O)C[C@H]1C(=O)O -US20150158851A1,1,CCOC(=O)c1n[nH]c2c1CCC(c1cnn(COCC[Si](C)(C)C)c1)C2.C[Si](C)(C)CCOCCl>>CCOC(=O)c1nn(COCC[Si](C)(C)C)c2c1CCC(c1cnn(COCC[Si](C)(C)C)c1)C2 -US20130143892A1,1,C1CC2(CCN1)OCCO2.CCc1cnc(Cl)nc1>>CCc1cnc(N2CCC3(CC2)OCCO3)nc1 -US20050209274A1,2,NC1CCN(Cc2ccc3c(c2)OCO3)CC1.O=C(O)c1cc(=O)c2ccc(OC(F)F)cc2o1>>O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2ccc(OC(F)F)cc2o1 -US20090186870A1,9,Cc1cc(C)n(-c2ccc(Cl)c(C(=O)O)c2)n1.N>>Cc1cc(C)n(-c2ccc(Cl)c(C(N)=O)c2)n1 -US08389524B2,1,NC1CCN(C[C@@H]2Cn3c(=O)ccc4ccc(=O)n2c43)CC1.O=Cc1ccc2c(c1)OCC2>>O=c1ccc2ccc(=O)n3c2n1C[C@H]3CN1CCC(NCc2ccc3c(c2)OCC3)CC1 -US06582351B1,6,COc1ccc(Cn2c(=O)n([C@@H]3CC[C@H](OC(C)=O)CC3)c3ncc(C#N)cc32)cc1Cl>>COc1ccc(Cn2c(=O)n([C@@H]3CC[C@H](O)CC3)c3ncc(C#N)cc32)cc1Cl -US06903115B2,2,CS(=O)(=O)c1cccc(C(=O)O)c1.O=C1CCNCC1>>CS(=O)(=O)c1cccc(C(=O)N2CCC(=O)CC2)c1 -US20110319378A1,9,CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1.N>>CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1 -US20100331320A1,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O.O=c1cc(I)cc[nH]1>>C[C@@H](c1ccc(-c2cc[nH]c(=O)c2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O -US06498165B1,3,C[C@H](Nc1nccc(-n2cnc3ccc(I)cc32)n1)c1ccccc1.OB(O)c1cccc2ccccc12>>C[C@H](Nc1nccc(-n2cnc3ccc(-c4cccc5ccccc45)cc32)n1)c1ccccc1 -US04902335,1,Cc1nc(CCl)no1.O=c1[nH]c2ccc(F)cc2s1>>Cc1nc(Cn2c(=O)sc3cc(F)ccc32)no1 -US20070299076A1,6,CC(C)(C)OC(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1N1CCCCC1=O>>CC(C)(C)OC(=O)N[C@H]1CNC[C@@H]1N1CCCCC1=O -US20100273806A1,9,N#C[Cu].O=C(O)c1ccc(OC2CCCC2)c(Br)c1>>N#Cc1cc(C(=O)O)ccc1OC1CCCC1 -US20080249301A1,9,COC(=O)c1sc(-n2cnc3ccc(CN4CCCN(C)CC4)cc32)cc1O[C@H](C)c1ccccc1Cl.N>>C[C@@H](Oc1cc(-n2cnc3ccc(CN4CCCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl -US04962203,1,CC(Br)C#N.Oc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1>>CC(C#N)Oc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 -US20030055269A1,2,CCOC(=O)c1c(N)sc(-c2ccc([N+](=O)[O-])cc2)c1C.O=C=Nc1ccccc1>>CCOC(=O)c1c(NC(=O)Nc2ccccc2)sc(-c2ccc([N+](=O)[O-])cc2)c1C -US05728835,2,COc1ccccc1N.O=S(=O)(Cl)c1ccc(F)cc1>>COc1ccccc1NS(=O)(=O)c1ccc(F)cc1 -US09023865B2,1,COC[C@@H](NC(N)=O)c1ccccc1.FC(F)(F)c1n[nH]c2cc(Cl)ncc12>>COC[C@@H](NC(=O)Nc1cc2[nH]nc(C(F)(F)F)c2cn1)c1ccccc1 -US20110160202A1,3,CON(C)C(=O)C1CCN(Cc2ccccc2)CC1.C[Mg+]>>CC(=O)C1CCN(Cc2ccccc2)CC1 -US09079888B2,7,O=[N+]([O-])c1ccc(OC2CCN(C3CCC3)CC2)cc1>>Nc1ccc(OC2CCN(C3CCC3)CC2)cc1 -US07968540B2,7,COC(=O)Cn1c(=O)n(Cc2ccc3cc4c(cc3n2)C[C@]2(C4)C(=O)NC(=O)N2C)c2cccc([N+](=O)[O-])c21>>COC(=O)Cn1c(=O)n(Cc2ccc3cc4c(cc3n2)C[C@]2(C4)C(=O)NC(=O)N2C)c2cccc(N)c21 -US20140038919A1,6,COc1ccc(CN(c2cc3oc(-c4ccc(F)cc4)c(-c4nc(C)c[nH]4)c3cc2C2CC2)S(C)(=O)=O)cc1>>Cc1c[nH]c(-c2c(-c3ccc(F)cc3)oc3cc(NS(C)(=O)=O)c(C4CC4)cc23)n1 -US20120142667A1,1,CS(=O)(=O)Nc1ccccc1Nc1nc(Cl)ncc1F.Nc1ccccc1F>>CS(=O)(=O)Nc1ccccc1Nc1nc(Nc2ccccc2F)ncc1F -US20150175604A1,2,CC(=O)Cl.Cc1nnc2ccc3c(cc(-c4ccn(C5(CC#N)CNC5)n4)n3Cc3cccc(Cl)c3)n12>>CC(=O)N1CC(CC#N)(n2ccc(-c3cc4c(ccc5nnc(C)n54)n3Cc3cccc(Cl)c3)n2)C1 -US06018046,1,CC(C)(C)OC(=O)CBr.O=c1ccn2c3ccc(Br)cc3c3cc(O)cc1c32>>CC(C)(C)OC(=O)COc1cc2c(=O)ccn3c4ccc(Br)cc4c(c1)c23 -US20080200672A1,7,CC(=O)c1cccnc1>>C[C@@H](O)c1cccnc1 -US07807684B2,6,CC(=O)Nc1ccc2[nH]cnc2c1Cl>>Nc1ccc2[nH]cnc2c1Cl -US06900210B2,2,Cc1ccc(Oc2cccc([C@H](C)N)c2)cn1.O=C(O)C=Cc1ccccc1F>>Cc1ccc(Oc2cccc([C@H](C)NC(=O)C=Cc3ccccc3F)c2)cn1 -US20070010511A1,1,COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1.O=[N+]([O-])c1cccc(CCl)c1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2cccc([N+](=O)[O-])c2)cc1 -US06403615B1,6,COc1ccc(C(=O)c2c(-c3ccc(OC)cc3)sc3cc(OC)ccc23)cc1>>COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(O)cc2)cc1 -US20120178736A1,6,CCN(Cc1ccccc1)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1>>CCNc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)n(C)c2n1 -US20080027050A1,9,COc1cncc(Br)c1.[C-]#N>>COc1cncc(C#N)c1 -US20040116471A1,1,CCOC(=O)N1CCC(c2c[nH]c3ccccc23)CC1.CS(=O)(=O)OCCc1ccsc1>>CCOC(=O)N1CCC(c2cn(CCc3ccsc3)c3ccccc23)CC1 -US20050107400A1,3,CCCC[Sn](CCCC)(CCCC)c1ccncc1.Fc1ccc(-c2nn3ccccc3c2Br)cc1>>Fc1ccc(-c2nn3ccccc3c2-c2ccncc2)cc1 -US20040220185A1,2,CS(=O)(=O)Cl.Ic1cnc(N2CCNCC2)nc1>>CS(=O)(=O)N1CCN(c2ncc(I)cn2)CC1 -US06194406B1,2,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.COc1ccc(C2C=NN=N2)cc1C(=O)O>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(C5C=NN=N5)ccc4OC)C3)CC2)nc2ccccc21 -US20030109527A1,7,O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)NCCOCc2ccccc2)c1O>>Nc1ccc(Cl)c(S(=O)(=O)NCCOCc2ccccc2)c1O -US20090111778A1,1,O=C(CCCC1CCNCC1)c1ncc(-c2ccco2)o1.O=Cc1ccccc1>>O=C(CCCC1CCN(Cc2ccccc2)CC1)c1ncc(-c2ccco2)o1 -US04920132,4,N#CCOc1cccc(COc2ccc(OCc3ccc4ccccc4n3)cc2)c1.[N-]=[N+]=[N-]>>c1cc(COc2ccc(OCc3ccc4ccccc4n3)cc2)cc(OCc2nnn[nH]2)c1 -US05426187,6,CC(C)(C)C(=O)Nc1nc(O)c2c(C#C[Si](C)(C)C)c[nH]c2n1>>C#Cc1c[nH]c2nc(NC(=O)C(C)(C)C)nc(O)c12 -US20090275598A1,6,COC(=O)CC(c1ccc(OC2CCC(c3ccccc3)CC2)cc1)c1cccs1>>O=C(O)CC(c1ccc(OC2CCC(c3ccccc3)CC2)cc1)c1cccs1 -US20130289033A1,9,CC[Si](CC)(CC)c1[nH]c2ncc(Cl)cc2c1CCN=[N+]=[N-]>>CC[Si](CC)(CC)c1[nH]c2ncc(Cl)cc2c1CCN -US06995182B2,7,COC(=O)CCC[C@H]1CC[C@@H](c2ccc(F)cc2)N1S(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)N2[C@@H](CCCCO)CC[C@H]2c2ccc(F)cc2)cc1 -US20140275049A1,6,COC(=O)c1ccc(-c2cc(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)n(-c3ccc(C(=O)N4CCCCC4)cc3)n2)cc1>>CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)nn2-c2ccc(C(=O)N3CCCCC3)cc2)cc(C(C)(C)C)c1 -US20150141400A1,1,CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(C=O)c(C(F)(F)F)cc2c1=O.CN(C[C@@H]1CCCNC1)C(=O)OC(C)(C)C>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCC[C@@H](CN(C)C(=O)OC(C)(C)C)C3)c(C(F)(F)F)cc2c1=O -US20100152252A1,3,CN(C)CCc1cccc(Br)c1.Cc1nn(C)c(C)c1B1OC(C)(C)C(C)(C)O1>>Cc1nn(C)c(C)c1-c1cccc(CCN(C)C)c1 -US20040214832A1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(OCc3ccccc3)cc2)[C@@H](COc2ccc3ccccc3c2)C1>>CC(C)(C)OC(=O)N1CCN(c2ccc(O)cc2)[C@@H](COc2ccc3ccccc3c2)C1 -US20130005707A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1ccc2c(c1)CNC2>>CC(C)(C)OC(=O)N1Cc2ccc(I)cc2C1 -US06703392B2,1,CCC(C)Br.COc1ccc(CC2c3c(O)ccc(OC)c3CCN2CC(=O)NCc2ccccn2)cc1OC>>CCC(C)Oc1ccc(OC)c2c1C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NCc1ccccn1)CC2 -US08129397B2,1,Cc1cc2c(=O)[nH]c(CCl)nc2s1.O=Cc1c[nH]nc1C(F)(F)F>>Cc1cc2c(=O)[nH]c(Cn3cc(C=O)c(C(F)(F)F)n3)nc2s1 -US20120245344A1,1,CS(=O)(=O)c1ccc2[nH]ccc2c1.Clc1ccc(CBr)nn1>>CS(=O)(=O)c1ccc2c(ccn2Cc2ccc(Cl)nn2)c1 -US08846661B2,3,Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1.COc1ccc(B(O)O)cc1F>>COc1ccc(-c2cncc(N3CC4CC5CC3CN(C5)C4)c2)cc1F -US08809304B2,1,CCCCCCCO.O=C(O)c1ccc(F)c(C(F)(F)F)c1>>CCCCCCCOc1ccc(C(=O)O)cc1C(F)(F)F -US20020128406A1,7,C=CCCC1(C)CC(=O)CC(C)(C)N1>>C=CCCC1(C)CCCC(C)(C)N1 -US20110207783A1,2,COCCCc1ccc(Cl)c(CNC2CC2)c1.N#CCC(=O)O>>COCCCc1ccc(Cl)c(CN(C(=O)CC#N)C2CC2)c1 -US05952355,1,COc1cc(C(=O)/C=C/c2c[nH]c3ccccc23)cc(OC)c1OC.Cc1oc(=O)oc1CCl>>COc1cc(C(=O)/C=C/c2cn(Cc3oc(=O)oc3C)c3ccccc23)cc(OC)c1OC -US08748422B2,2,NCCCN1CCCCC1.O=C(O)c1ccc2c(=O)n(Cc3ccc(Cl)cc3)c(=O)[nH]c2c1>>O=C(NCCCN1CCCCC1)c1ccc2c(=O)n(Cc3ccc(Cl)cc3)c(=O)[nH]c2c1 -US20140142097A1,3,Nc1ncc(Br)cc1C(=O)Nc1ccncc1.OB(O)c1ccc(O)cc1>>Nc1ncc(-c2ccc(O)cc2)cc1C(=O)Nc1ccncc1 -US03951876,6,CCCCCC1C(CC=O)CCC12OCCO2>>CCCCCC1C(=O)CCC1CC=O -US07799787B2,1,C[O-].FC(F)(F)c1ccccc1OC1CCN(c2ccc(Cl)nn2)CC1>>COc1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1 -US20040235919A1,1,CC(C(=O)O)c1ccc(NC(=O)OCCCl)cc1>>CC(C(=O)O)c1ccc(N2CCOC2=O)cc1 -US20070265281A1,6,CC(C)(C)OC(=O)N[C@]1(C(=O)NS(=O)(=O)c2cccc3cc[nH]c23)C[C@H]1C1CC1>>N[C@]1(C(=O)NS(=O)(=O)c2cccc3cc[nH]c23)C[C@H]1C1CC1 -US05753682,1,COC1(c2cccc(O)c2)CCOCC1.OCc1ccc(-n2ccnc2)cc1>>COC1(c2cccc(OCc3ccc(-n4ccnc4)cc3)c2)CCOCC1 -US20150152092A1,2,Cn1nccc1-c1cc(C(=O)O)oc1Cl.N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O>>Cn1nccc1-c1cc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)oc1Cl -US20070224695A1,9,O=c1cc(Cl)c2ccccc2o1.[N-]=[N+]=[N-]>>[N-]=[N+]=Nc1cc(=O)oc2ccccc12 -US08389717B2,1,COc1nc(Cl)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1.Cc1ncccc1O>>COc1nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)nc(Oc2cccnc2C)n1 -US20130035310A1,2,CC(C)(C(=O)O)n1ccc2ccc(C(F)(F)F)cc21.O=C1CNCCN1c1ccc(S(=O)(=O)Nc2nccs2)cc1>>CC(C)(C(=O)N1CCN(c2ccc(S(=O)(=O)Nc3nccs3)cc2)C(=O)C1)n1ccc2ccc(C(F)(F)F)cc21 -US20070099944A1,7,O=[N+]([O-])c1ccc2[nH]nc(Cl)c2c1>>Nc1ccc2[nH]nc(Cl)c2c1 -US20150152096A1,1,CCOC(=O)C1=C(CBr)NC(c2nccs2)=NC1c1ccc(F)cc1Cl.O=C(O)[C@@H]1COCCN1>>CCOC(=O)C1=C(CN2CCOC[C@H]2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl -US20080318255A1,2,CS(=O)(=O)Cl.OCCCCCCCCCCCN(Cc1ccccc1)Cc1ccccc1>>CS(=O)(=O)OCCCCCCCCCCCN(Cc1ccccc1)Cc1ccccc1 -US20150210682A1,1,COCCBr.COc1ccc(Br)cc1O>>COCCOc1cc(Br)ccc1OC -US20090082308A1,2,CCOC(=O)c1cc2ccc(CNCc3ccccc3)cc2s1.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)c1cc2ccc(CN(Cc3ccccc3)S(=O)(=O)c3ccccc3)cc2s1 -US20140005212A1,2,Nc1cccc(-c2ccc(Oc3ccc(F)cc3)cc2)n1.O=S(=O)(Cl)C=Cc1ccccc1>>O=S(=O)(/C=C/c1ccccc1)Nc1cccc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 -US20090318438A1,2,CCOC(=O)c1cccnc1OCc1ccc2c(c1)OCO2.NN>>NNC(=O)c1cccnc1OCc1ccc2c(c1)OCO2 -US05049497,8,O[C@H]1[C@H]2CCC=C[C@H]2C1(Cl)Cl>>O=C1[C@@H]2CCC=C[C@@H]2C1(Cl)Cl -US05049497,8,O[C@H]1[C@H]2CCC=C[C@H]2C1(Cl)Cl>>O=C1[C@H]2CCC=C[C@H]2C1(Cl)Cl -US20100280067A1,6,COc1ccc2c(c1)CCN(Cc1ccc(OCC3CC3)cc1)C2=O>>O=C1c2ccc(O)cc2CCN1Cc1ccc(OCC2CC2)cc1 -US20090062252A1,2,Cc1c(-c2ccc(C(=O)O)s2)noc1C(F)(F)F.OC1CCCNC1>>Cc1c(-c2ccc(C(=O)N3CCCC(O)C3)s2)noc1C(F)(F)F -US04883799,7,CC(C)(C)C(=O)Nc1nc(O)c2cc(C#CCOC3CCCCO3)cnc2n1>>CC(C)(C)C(=O)Nc1nc(O)c2cc(C=CCOC3CCCCO3)cnc2n1 -US20090247567A1,2,Nc1ccccc1Cl.O=C(Cl)c1cc2c(s1)-c1cc(Br)ccc1OCC2>>O=C(Nc1ccccc1Cl)c1cc2c(s1)-c1cc(Br)ccc1OCC2 -US08410150B2,1,CI.Cc1ccc(C#Cc2ccc(S(=O)(=O)N[C@H](CC(=O)OCc3ccccc3)CN(C)C)s2)cc1>>Cc1ccc(C#Cc2ccc(S(=O)(=O)N[C@H](CC(=O)OCc3ccccc3)C[N+](C)(C)C)s2)cc1 -US20050038035A1,1,CC1CN(c2ccc(NC(=O)C3=C(c4ccc(C(F)(F)F)cc4)CCCC3)cc2)CCN1.N#Cc1cccc(C=O)c1>>CC1CN(c2ccc(NC(=O)C3=C(c4ccc(C(F)(F)F)cc4)CCCC3)cc2)CCN1Cc1cccc(C#N)c1 -US06469021B1,2,COC(=O)c1cc2c3ccccc3n(Cc3cc(Cl)ccc3Cl)c2cn1.NN>>NNC(=O)c1cc2c3ccccc3n(Cc3cc(Cl)ccc3Cl)c2cn1 -US20100093761A1,2,CCCCOC(=O)Cl.CS(=O)(=O)c1ccc(-n2ncc3c(OC4CCNCC4)ncnc32)cc1>>CCCCOC(=O)N1CCC(Oc2ncnc3c2cnn3-c2ccc(S(C)(=O)=O)cc2)CC1 -US20150023990A1,1,CCCn1c(COC)nc2c(N)nc3ccc(O)cc3c21.CN1CCCC(CCl)C1>>CCCn1c(COC)nc2c(N)nc3ccc(OCC4CCCN(C)C4)cc3c21 -US20090258882A1,1,COc1ccc(-c2ccc3ncnc(Cl)c3c2)cc1OC.c1cn[nH]c1>>COc1ccc(-c2ccc3ncnc(-n4cccn4)c3c2)cc1OC -US20030232875A1,2,CCOC(=O)CN.O=C(O)c1cc2sc(Cl)c(Cl)c2[nH]1>>CCOC(=O)CNC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1 -US20130165464A1,9,N.O=C(O)c1cn(-c2ccnc(NCCc3ccc(O)cc3)n2)nc1-c1ccccc1Cl>>NC(=O)c1cn(-c2ccnc(NCCc3ccc(O)cc3)n2)nc1-c1ccccc1Cl -US20100120775A1,7,O=C(O)c1c(-c2c(Cl)cncc2Cl)noc1C1CCC1>>OCc1c(-c2c(Cl)cncc2Cl)noc1C1CCC1 -US04518597,8,CC1(C)OC(=O)Nc2ccc(OCCCCSc3ccc(C4CCCCC4)cc3)cc21.OO>>CC1(C)OC(=O)Nc2ccc(OCCCCS(=O)c3ccc(C4CCCCC4)cc3)cc21 -US06337344B1,6,C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(OCc4ccccc4)ccc3n2Cc2cccc(C(=N)N)c2)cc1>>C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(O)ccc3n2Cc2cccc(C(=N)N)c2)cc1 -US20140155389A1,1,COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1cc(Cl)nc2cn[nH]c(=O)c12.Oc1ccccc1Cl>>COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1cc(Oc2ccccc2Cl)nc2cn[nH]c(=O)c12 -US05472959,2,CO.NC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>COC(=O)[C@H](CN)NC(=O)OCc1ccccc1 -US20040106653A1,1,C[C@H](Cc1ccc(S)cc1)NC(=O)C(F)(F)F.O=Cc1ccc(F)cc1>>C[C@H](Cc1ccc(Sc2ccc(C=O)cc2)cc1)NC(=O)C(F)(F)F -US20060178438A1,2,CC(C)(C)OCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCOC(C)(C)C)cc1 -US05356922,9,Cn1cnc(Cl)c1S(=O)(=O)O>>Cn1cncc1S(=O)(=O)O -US20120142667A1,1,COc1ccc(Nc2nc(Cl)ncc2Cl)c(NS(C)(=O)=O)c1.COc1cccc(N)c1OC>>COc1ccc(Nc2nc(Nc3cccc(OC)c3OC)ncc2Cl)c(NS(C)(=O)=O)c1 -US06476038B1,7,Cc1cc(Cl)cc(C)c1C=O>>Cc1cc(Cl)cc(C)c1CO -US20140206681A1,6,COC(=O)[C@@H]1CC[C@H]2CO[C@@H](C)C(=O)N2C1>>C[C@@H]1OC[C@@H]2CC[C@@H](C(=O)O)CN2C1=O -US05952342,2,CC(C)(C)N=C=O.CCN(CC)CCCNc1ncc2cc(-c3c(Br)cccc3Br)c(N)nc2n1>>CCN(CC)CCCNc1ncc2cc(-c3c(Br)cccc3Br)c(NC(=O)NC(C)(C)C)nc2n1 -US20110105470A1,2,O=C(Cl)c1ccncc1.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccccc2C2=C1SCC1(CCN(C(=O)c3ccncc3)CC1)O2 -US20090176824A1,1,Cc1c(F)c(F)c(N)c2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12.F[C@@H]1CNC[C@@H]1CNC1CC1>>Cc1c(N2C[C@H](CNC3CC3)[C@H](F)C2)c(F)c(N)c2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12 -US06770646B2,9,CC(C)Cc1nn(C)c(=O)c2cc(C(O)c3ccccc3)sc12>>CC(C)Cc1nn(C)c(=O)c2cc(Cc3ccccc3)sc12 -US20090197915A1,9,ClC(Cl)(Cl)Cl.Cn1ccc2c1CCCC2CCO>>Cn1ccc2c1CCCC2CCCl -US20150094330A1,1,Brc1cccc2c1CNC2.COc1cccc(CBr)c1>>COc1cccc(CN2Cc3cccc(Br)c3C2)c1 -US20040006141A1,7,COC(=O)c1ccc(-c2cccc(C=O)c2)cc1>>COC(=O)c1ccc(-c2cccc(CO)c2)cc1 -US07999107B2,2,CC1(C)CC(C(=O)O)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2O1.NCCO>>CC1(C)CC(C(=O)NCCO)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2O1 -US20150045351A1,1,CC(C)(C)OC(=O)N1CCc2cccc3c2[C@H](CN3)C1.OB(O)C1CC1>>CC(C)(C)OC(=O)N1CCc2cccc3c2[C@@H](C1)CN3C1CC1 -US08183275B2,2,CCC(C)(C)Cc1c[nH]cn1.CN(C)S(=O)(=O)Cl>>CCC(C)(C)Cc1cn(S(=O)(=O)N(C)C)cn1 -US20140066424A1,7,Cc1nc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1cccc([N+](=O)[O-])c1>>Cc1nc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1cccc(N)c1 -US03980788,1,CN.O=C1CCCN(Cc2ccccc2)C1>>CNC1CCCN(Cc2ccccc2)C1 -US20090156575A1,2,CC1(C)Cc2cccc(CN3CCC4(CC3)CNC4)c2O1.O=C(O)c1ccncc1>>CC1(C)Cc2cccc(CN3CCC4(CC3)CN(C(=O)c3ccncc3)C4)c2O1 -US07119122B2,1,CN.COc1c(C=O)cccc1Oc1cc(Cl)ccc1C#N>>CNCc1cccc(Oc2cc(Cl)ccc2C#N)c1OC -US07786114B2,1,C1COCCN1.COc1cc2c(nc1OC)c(-c1cc3cccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2CCI>>COc1cc2c(nc1OC)c(-c1cc3cccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2CCN1CCOCC1 -US20090264428A1,1,CC(C)(C)OC(=O)N[C@@H]1CN(Cc2ccccc2)C[C@@H]1O.O=C(O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N[C@@H]1CN(Cc2ccccc2)C[C@H]1OC(=O)c1ccc([N+](=O)[O-])cc1 -US08501732B2,1,CNC(=O)c1ccc(S(C)(=O)=O)cc1.COC(=O)c1c(CBr)c(=O)c2ccc(Cl)cc2n1-c1ccccc1>>COC(=O)c1c(CN(C)C(=O)c2ccc(S(C)(=O)=O)cc2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 -US05602277,7,COC(=O)c1cc(C=NO)cc([N+](=O)[O-])c1>>COC(=O)c1cc(N)cc(C=NO)c1 -US20090047379A1,2,COC(=O)[C@H](C)N.Cc1ccc(C(=O)O)c(C)c1>>COC(=O)[C@H](C)NC(=O)c1ccc(C)cc1C -US20110124661A1,4,COc1cc(N)c(N)cc1C#N.O=C(n1ccnc1)n1ccnc1>>COc1cc2[nH]c(=O)[nH]c2cc1C#N -US07560558B2,8,Cc1ccc(C(O)c2cc(C)c(C)o2)nc1>>Cc1ccc(C(=O)c2cc(C)c(C)o2)nc1 -US05424280,6,COCOc1ccc([N+](=O)[O-])c(Oc2ccc(OCC(=O)OC)cc2)c1>>COC(=O)COc1ccc(Oc2cc(O)ccc2[N+](=O)[O-])cc1 -US20010006969A1,1,C=CCN.C=CCNc1nc(Cl)nc2c(-c3ccccc3)csc12>>C=CCNc1nc(NCC=C)c2scc(-c3ccccc3)c2n1 -US20010006969A1,1,C=CCNc1nc(Cl)nc2ccc([N+](=O)[O-])cc12.CC(C)N>>C=CCNc1nc(NC(C)C)nc2ccc([N+](=O)[O-])cc12 -US20120065193A1,3,CCOP(=O)(CC(=O)OC(C)(C)C)OCC.O=Cc1ccc(Br)cc1>>CC(C)(C)OC(=O)/C=C/c1ccc(Br)cc1 -US20040157894A1,2,CS(=O)(=O)Cl.O=C(c1ccccc1)c1ccc(CN2CC(O)CC2=O)cc1>>CS(=O)(=O)OC1CC(=O)N(Cc2ccc(C(=O)c3ccccc3)cc2)C1 -US07468391B2,6,COC(=O)Cc1ccc(C#Cc2cc(C(=O)OC(C)(C)C)c3c(c2)C(C)(C)CC(C)(C)O3)cc1>>CC(C)(C)OC(=O)c1cc(C#Cc2ccc(CC(=O)O)cc2)cc2c1OC(C)(C)CC2(C)C -US20090048343A1,6,CCOC(C(=O)O)c1ccc(NC(C)=O)cc1>>CCOC(C(=O)O)c1ccc(N)cc1 -US06727264B1,3,Brc1ccc2cc[nH]c2c1.Cc1ccccc1B(O)O>>Cc1ccccc1-c1ccc2cc[nH]c2c1 -US04230635,2,CN(C)S(=O)(=O)Cl.CNc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1>>CN(C)S(=O)(=O)N(C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 -US06350749B1,1,CCCn1ccc2c1CC(c1ccccc1)CC2=O.N=C(N)NN>>CCCn1ccc2c1CC(c1ccccc1)CC2=NNC(=N)N -US20100075953A1,1,ClCCCN1CCCCC1.Oc1ccc(Br)c(F)c1>>Fc1cc(OCCCN2CCCCC2)ccc1Br -US08410160B2,1,CN1CCNCC1.Cc1ccc(C(=O)NC2CC2)cc1-n1ncc(C(=O)c2cccc(OCCBr)c2)c1N>>Cc1ccc(C(=O)NC2CC2)cc1-n1ncc(C(=O)c2cccc(OCCN3CCN(C)CC3)c2)c1N -US07105671B2,6,COC(=O)C(CC1CCC(=O)C1)c1ccc(S(C)(=O)=O)c(Cl)c1>>CS(=O)(=O)c1ccc(C(CC2CCC(=O)C2)C(=O)O)cc1Cl -US07067658B2,1,CC[C@H](N)C1CC1.COc1cc(Cl)c(-c2ccnc(OS(=O)(=O)C(F)(F)F)c2[N+](=O)[O-])cc1F>>CC[C@H](Nc1nccc(-c2cc(F)c(OC)cc2Cl)c1[N+](=O)[O-])C1CC1 -US20150282482A1,3,COC(=O)c1cc2ccc(Br)cc2s1.OB(O)c1ccc(C(F)(F)F)nc1>>COC(=O)c1cc2ccc(-c3ccc(C(F)(F)F)nc3)cc2s1 -US20040010031A1,1,Nc1ccc(C(=O)c2ccccc2)cc1.O=C1NC(=O)C(c2ccc(Cl)cc2)=C1Cl>>O=C1NC(=O)C(c2ccc(Cl)cc2)=C1Nc1ccc(C(=O)c2ccccc2)cc1 -US07951806B2,6,COC(=O)CCCCC(=O)Nc1scc(-c2ccccc2)c1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)c1c(-c2ccccc2)csc1NC(=O)CCCCC(=O)O -US07858640B2,1,COC(=O)C(C)Br.Cc1c(Cc2ccc(Cl)cc2)c(=O)[nH]c2c(Cl)ccc(O)c12>>COC(=O)C(C)Oc1ccc(Cl)c2[nH]c(=O)c(Cc3ccc(Cl)cc3)c(C)c12 -US20110230493A1,3,CC(C)(C)OC(=O)N1CCC2(CC1)C[C@H](c1cccc(B3OC(C)(C)C(C)(C)O3)c1)CO2.FC(F)(F)c1ccc(Br)nc1>>CC(C)(C)OC(=O)N1CCC2(CC1)C[C@H](c1cccc(-c3ccc(C(F)(F)F)cn3)c1)CO2 -US20060142330A1,6,O=S(=O)(c1cccc(Cl)c1)c1cn(CC2CCCN2Cc2ccccc2)c2ncccc12>>O=S(=O)(c1cccc(Cl)c1)c1cn(CC2CCCN2)c2ncccc12 -US20100093865A1,3,C=CCNC(=O)C(F)(F)F.CCCCS(=O)(=O)c1cccc(Br)c1>>CCCCS(=O)(=O)c1cccc(/C=C/CNC(=O)C(F)(F)F)c1 -US08207216B2,1,CC(=O)OCc1ccc(C(=O)CCl)c(O)c1>>CC(=O)OCc1ccc2c(c1)OCC2=O -US20080312185A1,3,C#CC1CC1.COC(=O)Cl>>COC(=O)C#CC1CC1 -US07582785B2,3,C#CC[C@H](/C=C/C=C/C#C[C@H](CCCC(=O)OC)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C.CC[C@H](/C=C/I)O[Si](C)(C)C(C)(C)C>>CC[C@H](/C=C/C#CC[C@H](/C=C/C=C/C#C[C@H](CCCC(=O)OC)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C -US08026257B2,1,C=O.Cn1cc2cc(C(F)(F)F)cc(COCC3(c4ccccc4)CCNCC3)c2n1>>CN1CCC(COCc2cc(C(F)(F)F)cc3cn(C)nc23)(c2ccccc2)CC1 -US20130196993A1,1,CNCCNC.Cc1cc(Cl)c2ccccc2n1>>CNCCN(C)c1cc(C)nc2ccccc12 -US20070254882A1,6,CCOC(=O)CN(Cc1ccc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)cc1)S(=O)(=O)N1CCCc2ccccc21>>Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCOc1ccc(CN(CC(=O)O)S(=O)(=O)N2CCCc3ccccc32)cc1 -US20070232607A1,1,CC(C)(C)C(=O)OCCl.COc1cccc2nc[nH]c(=O)c12>>COc1cccc2ncn(COC(=O)C(C)(C)C)c(=O)c12 -US08097628B2,1,FC(F)(F)c1ccc(CBr)nn1.NC1CCN(CC2Cn3c(=O)ccc4ncc(=O)n2c43)CC1>>O=c1ccc2ncc(=O)n3c2n1CC3CN1CCC(NCc2ccc(C(F)(F)F)nn2)CC1 -US07553979B2,6,COc1cc(OC)c2c(c1)OCCCCC=CCCCCOC2=O>>COc1cc(O)c2c(c1)OCCCCC=CCCCCOC2=O -US05620974,2,COc1cc(C)c(N)c(Br)n1.O=C(Cl)c1cccnc1Cl>>COc1cc(C)c(NC(=O)c2cccnc2Cl)c(Br)n1 -US06063928,1,BrCc1ccc(I)cc1.Cc1ncc[nH]1>>Cc1nccn1Cc1ccc(I)cc1 -US20150210688A1,2,CN.Cc1nc(C(=O)O)c[nH]1>>CNC(=O)c1c[nH]c(C)n1 -US20090181942A1,6,CCOC(=O)Cn1nnc(CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)n1>>COc1cccc([C@H]2O[C@H](CCc3nnn(CC(=O)O)n3)c3cccn3-c3ccc(Cl)cc32)c1OC -US07915267B2,1,N#Cc1cccc(OCCCCl)c1.c1c[nH]cn1>>N#Cc1cccc(OCCCn2ccnc2)c1 -US20060160832A1,2,COCCN.COc1cc2nccc(Oc3ccc4[nH]ccc4c3)c2cc1C(=O)O>>COCCNC(=O)c1cc2c(Oc3ccc4[nH]ccc4c3)ccnc2cc1OC -US20130131043A1,1,Clc1ncc2cn[nH]c2n1.Nc1cnn(CC(F)F)c1>>FC(F)Cn1cc(Nc2ncc3cn[nH]c3n2)cn1 -US20090118288A1,6,COC(=O)c1ccc(SCC(=O)OC(C)(C)C)nc1N>>COC(=O)c1ccc(SCC(=O)O)nc1N -US08673942B2,1,CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(O)c2[nH]1.Clc1cccc(CBr)n1>>CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(OCc3cccc(Cl)n3)c2[nH]1 -US20110245296A1,9,N#C[Cu].Oc1nccc(C(F)(F)F)c1Oc1cc(Cl)cc(Br)c1>>N#Cc1cc(Cl)cc(Oc2c(C(F)(F)F)ccnc2O)c1 -US08058269B2,2,CC(=O)N[C@H]1CCCNC1.O=C(O)c1ccc(Br)cc1NC1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc21>>CC(=O)N[C@H]1CCCN(C(=O)c2ccc(Br)cc2NC2(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc32)C1 -US20100035917A1,3,CC(C)(O)CNS(=O)(=O)c1ccc(Br)cc1.OB(O)c1ccnc2[nH]c(C3CC3)cc12>>CC(C)(O)CNS(=O)(=O)c1ccc(-c2ccnc3[nH]c(C4CC4)cc23)cc1 -US20060166983A1,7,COC(=O)c1sc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)nc1C>>Cc1nc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)sc1CO -US07855216B2,9,O=S(=O)(Cl)c1ccc(Br)c(Cl)c1>>Sc1ccc(Br)c(Cl)c1 -US20100004238A1,7,O=[N+]([O-])c1ccc(Oc2ccc(Cl)c3[nH]ncc23)c(Cl)c1>>Nc1ccc(Oc2ccc(Cl)c3[nH]ncc23)c(Cl)c1 -US20140323537A1,1,O=[N+]([O-])c1ccc(F)c(F)c1.Oc1ccccc1>>O=[N+]([O-])c1ccc(Oc2ccccc2)c(F)c1 -US04066772,1,O=c1[nH]c2cc(Cl)ccc2n1C1CCNCC1.O=c1[nH]c2cc(Cl)ccc2n1CCCO>>O=c1[nH]c2cc(Cl)ccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1 -US20150166480A1,2,CCC(F)(CC)CN1CCC(COc2ccc(-c3ccc(C(=O)O)cc3)cc2)CC1.O[C@@H]1CCCNC1>>CCC(F)(CC)CN1CCC(COc2ccc(-c3ccc(C(=O)N4CCC[C@@H](O)C4)cc3)cc2)CC1 -US05208259,1,CCC(=O)Nc1ccc(Sc2cccc(C3(OC)CCOCC3)c2)cc1Cl.CI>>CCC(=O)N(C)c1ccc(Sc2cccc(C3(OC)CCOCC3)c2)cc1Cl -US04251262,8,COCCSc1nc[nH]n1.OO>>COCCS(=O)c1nc[nH]n1 -US05093026,7,CCCCCc1ccc(-c2ccc(C=Cc3ccc(OCC)cc3)cc2)cc1>>CCCCCc1ccc(-c2ccc(CCc3ccc(OCC)cc3)cc2)cc1 -US20090124796A1,3,CC(=O)Nc1cc[nH]c(=O)n1.FC(F)(F)I>>CC(=O)Nc1nc(=O)[nH]cc1C(F)(F)F -US20070232632A1,1,CS(=O)(=NC(=O)NC1CCCC1)c1ccc(N)cc1.C[C@H](CO)Nc1nc(Cl)ncc1-c1cccs1>>C[C@H](CO)Nc1nc(Nc2ccc(S(C)(=O)=NC(=O)NC3CCCC3)cc2)ncc1-c1cccs1 -US07776847B2,1,Cc1cccc2snc(Br)c12.NCCCN>>Cc1cccc2snc(NCCCN)c12 -US05102667,2,O=C(O)Cc1cccnc1.O=C1CCC(c2ccccc2)(c2ccccc2)C2CNCC12>>O=C1CCC(c2ccccc2)(c2ccccc2)C2CN(C(=O)Cc3cccnc3)CC12 -US08124606B2,1,CCNC(=O)c1ccc(N2CCNCC2)c(F)c1.O=C1Nc2cc(CO)cnc2N2CCC[C@@H]12>>CCNC(=O)c1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCN43)CC2)c(F)c1 -US08415378B2,6,COC(=O)C1CCN(C(=O)OC)C(c2ccc(C(F)(F)F)nc2)C1>>COC(=O)N1CCC(C(=O)O)CC1c1ccc(C(F)(F)F)nc1 -US20070123527A1,2,CS(=O)(=O)Cl.N#Cc1c[nH]c2cccc(C(CCO)c3ccccc3)c12>>CS(=O)(=O)OCCC(c1ccccc1)c1cccc2[nH]cc(C#N)c12 -US06048989,3,CCOc1ccc(C=O)cc1.O=C(O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCOc1ccc(C=CCCCCC(=O)O)cc1 -US04879389,7,CCOC(=O)[C@@H]1C[C@@H](O)CN1S(C)(=O)=O>>CS(=O)(=O)N1C[C@H](O)C[C@H]1CO -US20090062360A1,2,COc1ccccc1N.O=C(Cl)CN1C(=O)C(c2ccc(C(F)(F)F)cc2)=NC12CCCCC2>>COc1ccccc1NC(=O)CN1C(=O)C(c2ccc(C(F)(F)F)cc2)=NC12CCCCC2 -US07863329B2,7,COC(=O)CCNC(=O)c1ccc(C(=Cc2ccc(-c3ccc(C(C)(C)C)cc3)cc2)CC(C)C)cc1>>COC(=O)CCNC(=O)c1ccc(C(Cc2ccc(-c3ccc(C(C)(C)C)cc3)cc2)CC(C)C)cc1 -US20150225412A1,2,C=CC(=O)Cl.O=C(Nc1nc2ccccc2n1C1CCNCC1)c1ccc(Cl)cc1>>C=CC(=O)N1CCC(n2c(NC(=O)c3ccc(Cl)cc3)nc3ccccc32)CC1 -US05968819,1,Clc1nc(Cl)c2ccccc2n1.Nc1ccccc1>>Clc1nc(Nc2ccccc2)c2ccccc2n1 -US20140005168A1,7,C=C(C)c1cncc(-c2cc3c(cn2)cnn3-c2cccc(F)n2)c1>>CC(C)c1cncc(-c2cc3c(cn2)cnn3-c2cccc(F)n2)c1 -US20110076291A1,3,CC(C)(O)Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.CC(C)n1nc(N)nc1-c1nc2c(s1)CCOc1cc(Br)ccc1-2>>CC(C)n1nc(N)nc1-c1nc2c(s1)CCOc1cc(-c3cnn(CC(C)(C)O)c3)ccc1-2 -US06147097,6,CC(C)c1nc(COCc2ccccc2)n(CCCc2ccccn2)c1Sc1cc(Cl)cc(Cl)c1>>CC(C)c1nc(CO)n(CCCc2ccccn2)c1Sc1cc(Cl)cc(Cl)c1 -US20120108583A1,2,COC(=O)c1cc2nc(Nc3c(F)cccc3Cl)[nH]c2c2c1OC(C)(C)C2.Nc1cc(F)c(F)cc1F>>CC1(C)Cc2c(c(C(=O)Nc3cc(F)c(F)cc3F)cc3nc(Nc4c(F)cccc4Cl)[nH]c23)O1 -US20130040951A9,3,COc1cc(C=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F.O=C1CSC(=O)N1>>COc1cc(/C=C2\SC(=O)NC2=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F -US06384051B1,1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Cc1c(N)cccc1CO>>COc1cc2ncc(C#N)c(Nc3cccc(CO)c3C)c2cc1OC -US05134128,3,CC(C)=CCC[Mg+].C[Si](C)(C)c1cc(C=O)co1>>CC(C)=CCCC(O)c1coc([Si](C)(C)C)c1 -US07834019B2,1,CCCC[Sn](Cl)(CCCC)CCCC.OC1(c2cccc(Br)n2)CCC1>>CCCC[Sn](CCCC)(CCCC)c1cccc(C2(O)CCC2)n1 -US20150284411A1,3,CB(O)O.O[C@@H]1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccc(-n7cncn7)cc6)cc5)c(Cl)cc4[nH]3)CO[C@H]12>>Cc1cc2[nH]c(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)nc2nc1-c1ccc(-c2ccc(-n3cncn3)cc2)cc1 -US03987171,2,CCC(=O)Nc1nc2ccc(Cl)cc2nc1N.CCCCCC(=O)Cl>>CCCCCC(=O)Nc1nc2cc(Cl)ccc2nc1NC(=O)CC -US20150284367A1,1,Cc1ccc(Nc2cc(Cl)nnc2C(N)=O)nc1C(C)C.NCCN>>Cc1ccc(Nc2cc(NCCN)nnc2C(N)=O)nc1C(C)C -US04259249,1,C=CCCC(=O)O.CCI>>C=CCCC(=O)OCC -US08404680B2,7,CCOC(=O)C1=NO[C@@H]2COC[C@H]12>>OCC1=NO[C@@H]2COC[C@H]12 -US20100069436A1,1,CC(O)CN.CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(F)c2)n1C>>CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCC(C)O)c2)n1C -US20100280067A1,1,CCI.Cc1ccc(O)cc1[N+](=O)[O-]>>CCOc1ccc(C)c([N+](=O)[O-])c1 -US06331637B1,2,Cc1noc(N)c1Br.O=S(=O)(Cl)c1ccsc1Cc1ccc2c(c1)OCO2>>Cc1noc(NS(=O)(=O)c2ccsc2Cc2ccc3c(c2)OCO3)c1Br -US20090221555A1,1,CCN1C(=O)CCCc2c1ccc(N)c2OC.Clc1ncc(Cl)c(Nc2ccccc2-n2cccn2)n1>>CCN1C(=O)CCCc2c1ccc(Nc1ncc(Cl)c(Nc3ccccc3-n3cccn3)n1)c2OC -US09120776B2,7,CC(C)Cn1c2c(c3cc([N+](=O)[O-])ccc31)CCCC2>>CC(C)Cn1c2c(c3cc(N)ccc31)CCCC2 -US20150183801A1,3,O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@H](O)C2)c(Br)c1.OB(O)c1cncnc1>>O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@H](O)C2)c(-c2cncnc2)c1 -US20080306082A1,6,COC(=O)c1ccc2cc(-c3nc(NCCCN4CCN(C)CC4)ncc3Cl)sc2c1>>CN1CCN(CCCNc2ncc(Cl)c(-c3cc4ccc(C(=O)O)cc4s3)n2)CC1 -US08877778B2,2,CC(C)(O)CC(=O)O.N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1>>CC(C)(O)CC(=O)N[C@@H]1CC[C@@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1 -US04999356,1,Fc1ccccc1C(=NNc1ccccc1)N1CCN(c2ccccc2)CC1>>c1ccc(N2CCN(c3nn(-c4ccccc4)c4ccccc34)CC2)cc1 -US07217740B2,7,O=S(=O)(c1ccccc1)c1ccc(/C=C/c2ccc(F)cc2F)nc1>>O=S(=O)(c1ccccc1)c1ccc(CCc2ccc(F)cc2F)nc1 -US20130184249A1,6,CCOC(=O)C1CCN(c2ccc(C#N)nc2)CC1>>N#Cc1ccc(N2CCC(C(=O)O)CC2)cn1 -US07326794B2,2,CCOC(=O)C(CC)CN[C@@H](C)C(=O)O.CCOC(=O)Cl>>CCOC(=O)C(CC)CN(C(=O)OCC)[C@@H](C)C(=O)O -US08664220B2,3,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cccc(Br)c4)cc3)cc2)CC1.OB(O)c1cccnc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Nc4cccc(-c5cccnc5)c4)cc3)cc2)CC1 -US20090023729A1,1,ClCc1nccn1Cc1ccccc1.FC(F)(F)c1cc(CNc2ncc(Br)cn2)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(CN(Cc2nccn2Cc2ccccc2)c2ncc(Br)cn2)cc(C(F)(F)F)c1 -US20090181942A1,1,CCOc1c(OC)cccc1C(O)c1cc(Cl)ccc1N.COc1ccc(C=O)c(OC)c1>>CCOc1c(OC)cccc1C(O)c1cc(Cl)ccc1NCc1ccc(OC)cc1OC -US05703125,6,CCOC(=O)C(CNC(=O)CCC(=O)Nc1ccc(C=NN)cc1)c1c(F)c(F)c(F)c(F)c1F>>NN=Cc1ccc(NC(=O)CCC(=O)NCC(C(=O)O)c2c(F)c(F)c(F)c(F)c2F)cc1 -US05455246,2,CCOCC(=O)O.NC1CCN(CC23CC(c4ccccc42)c2ccc(Cl)cc23)CC1>>CCOCC(=O)NC1CCN(CC23CC(c4ccccc42)c2ccc(Cl)cc23)CC1 -US07449466B2,1,COCOc1ccc(N2CCNCC2)cc1Cl.O=C(CBr)c1ccccc1>>COCOc1ccc(N2CCN(CC(=O)c3ccccc3)CC2)cc1Cl -US07732466B2,6,CC(=O)Nc1ccc(C(=O)N2CCOCC2)c(C)c1>>Cc1cc(N)ccc1C(=O)N1CCOCC1 -US20060241172A1,9,[N-]=[N+]=NCC1COc2cccc(-c3ccccc3Cl)c2O1>>NCC1COc2cccc(-c3ccccc3Cl)c2O1 -US20030055071A1,2,COC(=O)c1ncc2cccnc2c1O.NCc1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)c1ncc2cccnc2c1O -US05643908,2,CC(C)[C@H]1COC(=O)N1.O=C(Cl)CCCc1ccccc1>>CC(C)[C@H]1COC(=O)N1C(=O)CCCc1ccccc1 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)cn3)c(F)c2)OC1(C)C.O=S(=O)(c1ccccc1Br)N1CCC(O)(c2ccccc2)C1>>Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCC(O)(c4ccccc4)C3)cc2F)cn1 -US20050020654A1,7,CCCc1nc2c(C)cc(Br)cc2n1CC(=O)OCC>>CCCc1nc2c(C)cc(Br)cc2n1CCO -US04310527,1,CCOC(=O)CBr.O=[N+]([O-])c1cccc(OC2CCCCO2)c1O>>CCOC(=O)COc1c(OC2CCCCO2)cccc1[N+](=O)[O-] -US20120208827A1,1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.O=[N+]([O-])c1cccc(C(F)(F)F)c1F>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2c([N+](=O)[O-])cccc2C(F)(F)F)C1 -US07211577B2,1,CC(C)(C)OC(=O)N1CCNCC1.COc1ccc(-c2cc(COS(C)(=O)=O)c(=O)n(CC3CCCC3)n2)cc1F>>COc1ccc(-c2cc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(=O)n(CC3CCCC3)n2)cc1F -US04663353,2,CCCCCCCCC(=O)Cl.Nc1cc(Cl)ccc1O>>CCCCCCCCC(=O)Nc1cc(Cl)ccc1O -US07790895B2,3,CCOC(=O)c1cnc2cc(C(F)(F)F)ccc2c1OS(=O)(=O)C(F)(F)F.Cc1ccc(B(O)O)cc1C>>CCOC(=O)c1cnc2cc(C(F)(F)F)ccc2c1-c1ccc(C)c(C)c1 -US07419972B2,8,COCc1cc2c(cc1O)CC[C@H]1[C@@H]3CC[C@H](O)[C@@]3(C)CC[C@H]21>>COCc1cc2c(cc1O)CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@H]21 -US05726063,1,CC(=O)c1cccs1.NNc1cccc(F)c1>>CC(=NNc1cccc(F)c1)c1cccs1 -US20110054168A1,1,CCCCO.Clc1nc(NCc2ccccc2)c2ncn(C3CCCCO3)c2n1>>CCCCOc1nc(NCc2ccccc2)c2ncn(C3CCCCO3)c2n1 -US08802679B2,7,CN(Cc1cccc(-c2ccc(C#N)cc2)c1)C(=O)CNC(=O)OC(C)(C)C>>CN(Cc1cccc(-c2ccc(CN)cc2)c1)C(=O)CNC(=O)OC(C)(C)C -US20060058361A1,1,Cc1c(O)ccc(Cl)c1C.O=Cc1ccc(Br)cc1F>>Cc1c(Cl)ccc(Oc2cc(Br)ccc2C=O)c1C -US20050096380A1,6,COc1c(C(C)=O)cc2c(c1Br)C(C)(C)CC=C2C(C)C>>CC(=O)c1cc2c(c(Br)c1O)C(C)(C)CC=C2C(C)C -US07635715B2,6,COC(=O)C(C)(C)c1ccc(Br)cc1>>CC(C)(C(=O)O)c1ccc(Br)cc1 -US06987116B2,6,CCOC(=O)c1cnc2ccsc2c1Cl>>O=C(O)c1cnc2ccsc2c1Cl -US20100256169A1,9,C=CCn1c(=O)n([C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)c2nc(N)nc(Cl)c21>>C=CCn1c(=O)n([C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)c2nc(N)ncc21 -US20110212939A1,2,CC(=O)OC(C)=O.CC(C)OC(=O)N1CCC(CCCOc2ccc(C(=O)NN)c(F)c2)CC1>>CC(=O)NNC(=O)c1ccc(OCCCC2CCN(C(=O)OC(C)C)CC2)cc1F -US05053509,6,CCOC(=O)c1cn(OC)c2nc3cc(F)c(F)cc3cc2c1=O>>COn1cc(C(=O)O)c(=O)c2cc3cc(F)c(F)cc3nc21 -US05821245,3,CN1CCC(c2cccc3ccc(OS(=O)(=O)C(F)(F)F)cc23)CC1.C[Sn](C)(C)c1cncnc1>>CN1CCC(c2cccc3ccc(-c4cncnc4)cc23)CC1 -US05380865,1,N#C/C(N)=C(/N)C#N.O=Cc1c(Cl)cc(C(F)(F)F)cc1Cl>>N#CC(N)=C(C#N)N=Cc1c(Cl)cc(C(F)(F)F)cc1Cl -US05262436,2,CC(=O)SCC(Cc1ccccc1)C(=O)O.CCOC(=O)[C@@H](N)CSCCc1ccccc1>>CCOC(=O)[C@H](CSCCc1ccccc1)NC(=O)C(CSC(C)=O)Cc1ccccc1 -US04975438,1,CCCCC/C(=C\C=C\C(=O)O)c1ccc(OC)cc1.O=[N+]([O-])c1ccc(O)cc1>>CCCCC/C(=C\C=C\C(=O)Oc1ccc([N+](=O)[O-])cc1)c1ccc(OC)cc1 -US20150175601A1,7,CN1CCC(Nc2ccc([N+](=O)[O-])c(F)c2)CC1>>CN1CCC(Nc2ccc(N)c(F)c2)CC1 -US20090163517A1,1,CCOc1cc(C=O)cc(OCC)c1F.c1ncn(CCCOc2ccc3oc(NC4CCNCC4)nc3c2)n1>>CCOc1cc(CN2CCC(Nc3nc4cc(OCCCn5cncn5)ccc4o3)CC2)cc(OCC)c1F -US04075001,2,CCN(C)c1nsc(N)c1C#N.CN=C=O>>CCN(C)c1nsc(NC(=O)NC)c1C#N -US20140005168A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC1CNCCN(c2cccc(Br)n2)C1>>CC(C)(C)OC(=O)N1CCN(c2cccc(Br)n2)CC(O)C1 -US06967198B2,2,CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc(O)cc1)C(=O)O.Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc(O)cc1)C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O -US04026891,7,CC(=O)Nc1ccc(C2=NNC(=O)C(C)C2)cc1[N+](=O)[O-]>>CC(=O)Nc1ccc(C2=NNC(=O)C(C)C2)cc1N -US07342012B2,6,CC(C)(C)OC(=O)N1CCN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)C2(Cc2ccc(Br)cc2)C1>>O=C1N(c2cc(Cl)cc(Cl)c2)C(=O)C2(Cc3ccc(Br)cc3)CNCCN12 -US04443607,2,CC(=O)O.CC(N)Cn1cc(-c2ccccc2)c2ccccc2c1=O>>CC(=O)NC(C)Cn1cc(-c2ccccc2)c2ccccc2c1=O -US20020077320A1,6,CCOC(Cc1ccc(OCCN2c3ccccc3Sc3ccccc32)cc1)C(=O)OC>>CCOC(Cc1ccc(OCCN2c3ccccc3Sc3ccccc32)cc1)C(=O)O -US08263610B2,6,COc1ccc(Cn2ncc3c4c(cnc32)CN(C(=O)Cc2ccccc2)CC4)cc1>>O=C(Cc1ccccc1)N1CCc2c(cnc3[nH]ncc23)C1 -US07745438B2,2,CC(=O)OC(C)=O.CCCOc1cc(F)cc(CC(N)C(O)[C@H]2CO[C@@H](OCC(C)(C)C)[C@H](C)N2C(=O)OC(C)(C)C)c1>>CCCOc1cc(F)cc(C[C@H](NC(C)=O)[C@H](O)[C@H]2CO[C@@H](OCC(C)(C)C)[C@H](C)N2C(=O)OC(C)(C)C)c1 -US20100261719A1,1,CC1CNCC(C)O1.O=Cc1cc(I)c(F)c(F)c1F>>C[C@H]1CN(c2c(C=O)cc(I)c(F)c2F)C[C@@H](C)O1 -US20060040919A1,7,CC(=O)N1CCc2ccccc2C1[N+](=O)[O-]>>CC(=O)N1CCc2ccccc2C1N -US05736539,1,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@@H]1CCO.CI>>COCC[C@H]1CN(Cc2ccccc2)CCN1C(=O)OC(C)(C)C -US20100317582A1,7,COC(=O)CCc1ccc([C@H]2CC[C@H](N[C@H](C)c3cccc4ccccc34)C2)cc1>>C[C@@H](N[C@H]1CC[C@H](c2ccc(CCCO)cc2)C1)c1cccc2ccccc12 -US20090270383A1,9,BrC(Br)(Br)Br.N#Cc1ccc(CO)c(F)c1>>N#Cc1ccc(CBr)c(F)c1 -US20090099183A1,1,COc1ccc(Cl)cc1-c1cc(Cl)nc(N)n1.N#Cc1ccc(N)cc1>>COc1ccc(Cl)cc1-c1cc(Nc2ccc(C#N)cc2)nc(N)n1 -US20150252048A1,1,C=CC(=O)Nc1cccc(-c2nc(Cl)ncc2Cl)c1.Nc1cccc(N2CCOCC2)c1>>C=CC(=O)Nc1cccc(-c2nc(Nc3cccc(N4CCOCC4)c3)ncc2Cl)c1 -US20120108577A1,6,CC(=O)Nc1cc(F)cc(Br)c1>>Nc1cc(F)cc(Br)c1 -US20080221178A1,1,CC(=O)Nc1ccc(F)c([N+](=O)[O-])c1.CCI>>CCN(C(C)=O)c1ccc(F)c([N+](=O)[O-])c1 -US20070185075A1,1,CN(C(=O)OC(C)(C)C)C1CNC1.Clc1cc(Cl)ncn1>>CN(C(=O)OC(C)(C)C)C1CN(c2cc(Cl)ncn2)C1 -US06967198B2,2,C/C=C/C=C/C(=O)O.Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>C/C=C/C=C/C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O -US20150105373A1,9,CC(C)(F)C(Br)c1ccc(OC(F)(F)F)cc1.[N-]=[N+]=[N-]>>CC(C)(F)C(N=[N+]=[N-])c1ccc(OC(F)(F)F)cc1 -US20100331293A1,2,Cc1c(N2CCNCC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1.O=S(=O)(Cl)c1ccccc1F>>Cc1c(N2CCN(S(=O)(=O)c3ccccc3F)CC2)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1 -US20130085161A1,7,COC(=O)c1cccc2c1ccn2C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1ccc2c(CO)cccc21 -US20120184561A1,2,CCN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1.O=C(O)Cc1ccc(-n2cnc3cccnc32)cc1>>CCN1CCN(Cc2ccc(NC(=O)Cc3ccc(-n4cnc5cccnc54)cc3)cc2C(F)(F)F)CC1 -US05677336,7,CC1(C)CC=CC(=O)C1Cc1ccc([N+](=O)[O-])cc1>>CC1(C)CCCC(=O)C1Cc1ccc([N+](=O)[O-])cc1 -US06147097,6,CC(C)c1c(Sc2cccc(Cl)c2)nc(COCc2ccccc2)n1C>>CC(C)c1c(Sc2cccc(Cl)c2)nc(CO)n1C -US20140364433A1,1,Cc1ccc(-c2ncccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.N#Cc1ccc(Cl)nc1>>Cc1ccc(-c2ncccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ccc(C#N)cn2)c1 -US20090093454A1,1,Cn1c(C=O)nc2cccc(N3CCN(C(=O)OC(C)(C)C)CC3)c21.c1cnc2c(c1)CC[C@@H]1CCCN[C@H]21>>Cn1c(CN2CCC[C@H]3CCc4cccnc4[C@H]32)nc2cccc(N3CCN(C(=O)OC(C)(C)C)CC3)c21 -US20070082899A1,6,CC(=O)N(C)c1ccc2c(c1)nc(C(F)(F)F)n2CC1CCOCC1>>CNc1ccc2c(c1)nc(C(F)(F)F)n2CC1CCOCC1 -US04051260,1,CC(C=O)c1ccc2c(=O)c3ccccc3ccc2c1.NNC(N)=O>>CC(C=NNC(N)=O)c1ccc2c(=O)c3ccccc3ccc2c1 -US07388011B2,1,CS(=O)(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CCC=O)C1.O=[N+]([O-])c1cccc(Cl)c1N1CCNCC1>>CS(=O)(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CCCN2CCN(c3c(Cl)cccc3[N+](=O)[O-])CC2)C1 -US20100136136A1,1,CI.Nc1c(O)cccc1[N+](=O)[O-]>>COc1cccc([N+](=O)[O-])c1N -US20110190227A1,6,COc1ccc(CC(=O)O[C@@H]2O[C@@H](C(=O)OCc3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)cc1Oc1ccc(NC(=O)C(C)(C)C)cc1CSC(C)(C)C>>COc1ccc(CC(=O)O[C@@H]2O[C@@H](C(=O)O)[C@H](O)[C@@H](O)[C@@H]2O)cc1Oc1ccc(NC(=O)C(C)(C)C)cc1CSC(C)(C)C -US08026257B2,3,C[Mg+].C[Si](C)(C)CCOCn1cc(C#N)c2cc(Cl)cc(C=O)c21>>CC(O)c1cc(Cl)cc2c(C#N)cn(COCC[Si](C)(C)C)c12 -US05614633,8,FCC1(CF)C=C(c2ccccn2)c2cc(I)ccc2O1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccccc1C1=CC(CF)(CF)Oc2ccc(I)cc21 -US20040132727A1,2,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C(N=C=S)c1ccc(C2CCCCC2)cc1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccc(C5CCCCC5)cc4)cc3)c2cc1OC -US05320825,1,Cc1cc(I)ccc1O.O[C@H](CCCl)c1ccccc1>>Cc1cc(I)ccc1O[C@@H](CCCl)c1ccccc1 -US20140107139A1,1,CC1(C)OCc2ccc(O)cc21.CC[C@@]1(C)NC(=O)N(c2cnc(F)c(C)c2)C1=O>>CC[C@@]1(C)NC(=O)N(c2cnc(Oc3ccc4c(c3)C(C)(C)OC4)c(C)c2)C1=O -US20130225633A1,1,F[C@@H]1CCNC1.O=S(=O)(c1cccc(Br)c1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(COCC2CC2)C1>>O=S(=O)(c1cccc(N2CC[C@@H](F)C2)c1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(COCC2CC2)C1 -US05622976,2,CCOC(=O)c1noc(C2CN3CCC2CC3)n1.NCCC1CCN(Cc2ccccc2)CC1>>O=C(NCCC1CCN(Cc2ccccc2)CC1)c1noc(C2CN3CCC2CC3)n1 -US08778950B2,9,Fc1ccc(Br)nc1.NN>>NNc1ccc(Br)nc1 -US20060106048A1,6,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(NCc3ccccc3)c1)=NC(C)(C)C2>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)O)c(NCc3ccccc3)c1)=NC(C)(C)C2 -US08138175B2,7,COC(=O)[C@H](CCN1CCC2(CC2)[C@H](O)C1)N1C[C@@H](C)N(c2ccc(Cl)c(Cl)c2)CCC1=O>>C[C@@H]1CN([C@H](CO)CCN2CCC3(CC3)[C@H](O)C2)C(=O)CCN1c1ccc(Cl)c(Cl)c1 -US07199238B2,1,Clc1nc(Cl)nc(Nc2ccccc2)n1.Nc1ccc2c(c1)OCO2>>Clc1nc(Nc2ccccc2)nc(Nc2ccc3c(c2)OCO3)n1 -US07897607B2,1,CCC(Br)CC.Cc1ccc(-c2cccc3[nH]n(C)c(=O)c23)c(C)c1>>CCC(CC)n1c2cccc(-c3ccc(C)cc3C)c2c(=O)n1C -US20100041654A1,1,Nc1cccc(C(F)(F)F)c1F.O=C(NCC1CCC1)c1cnc(Cl)nc1C(F)(F)F>>O=C(NCC1CCC1)c1cnc(Nc2cccc(C(F)(F)F)c2F)nc1C(F)(F)F -US06693116B2,2,COc1ccc(-c2ccccc2)c2nc(N)nn12.O=C(O)c1cccc(F)c1>>COc1ccc(-c2ccccc2)c2nc(NC(=O)c3cccc(F)c3)nn12 -US20040110745A1,1,C1CSCCN1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(N2CCSCC2)cc1 -US07960369B2,3,COC(=O)CCc1ccc(OCc2cccc(Br)c2)cc1.C[Sn](C)(C)c1ccccn1>>COC(=O)CCc1ccc(OCc2cccc(-c3ccccn3)c2)cc1 -US20090105258A1,2,C=Cc1cc(CNC(=O)OC(C)(C)C)cc(C(F)(F)F)c1N.CS(=O)(=O)Cl>>C=Cc1cc(CNC(=O)OC(C)(C)C)cc(C(F)(F)F)c1NS(C)(=O)=O -US20140080861A1,3,C=O.CCCCCCC(=O)c1cccnc1>>C=C(CCCCC)C(=O)c1cccnc1 -US08344135B2,1,CC(C)(C)OC(=O)Nc1cc(N)c(Cl)cc1F.N#CSc1nc(Cl)ncc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(Nc2ncc([N+](=O)[O-])c(SC#N)n2)c(Cl)cc1F -US20090099231A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1cc2c(cc1F)CNCC2>>CC(C)(C)OC(=O)N1CCc2cc([N+](=O)[O-])c(F)cc2C1 -US05344968,1,CC(C)CO.O=C(O)c1ccccc1Cl>>CC(C)COc1ccccc1C(=O)O -US20100298287A1,1,C1CCNCC1.Cc1nc(OS(=O)(=O)C(F)(F)F)ccc1N1CCCn2c1nc1c(Cl)ccc(C(OC(F)F)C(F)(F)F)c12>>Cc1nc(N2CCCCC2)ccc1N1CCCn2c1nc1c(Cl)ccc(C(OC(F)F)C(F)(F)F)c12 -US04897420,6,COC1=C(OC)C(=O)C(CCCCC[C@@H]2CC[C@@H](OC(C)=O)CC2)=C(C)C1=O>>COC1=C(OC)C(=O)C(CCCCC[C@@H]2CC[C@@H](O)CC2)=C(C)C1=O -US20130079373A1,6,CCOC(=O)C(C)c1ccc(CNS(C)(=O)=O)c(F)c1>>CC(C(=O)O)c1ccc(CNS(C)(=O)=O)c(F)c1 -US20080312192A1,7,CCN1CCN(C(=O)c2ccc(N)cc2)CC1>>CCN1CCN(Cc2ccc(N)cc2)CC1 -US20120238571A1,1,CI.O=S(=O)(Nc1cc(Br)cnc1Cl)c1ccccc1>>CN(c1cc(Br)cnc1Cl)S(=O)(=O)c1ccccc1 -US07649093B2,6,CCCC(CC(=O)OCC)Cc1ccc(F)c(OC)c1>>CCCC(CC(=O)O)Cc1ccc(F)c(OC)c1 -US08329682B2,3,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.Fc1cccc(Br)c1F>>Fc1cccc(-c2cccc3[nH]ccc23)c1F -US20070106081A1,6,CCOC(=O)COc1ccc([SH](C)C(C)c2cccc3cn(-c4ccc(C(F)(F)F)cc4)nc23)cc1C>>Cc1cc([SH](C)C(C)c2cccc3cn(-c4ccc(C(F)(F)F)cc4)nc23)ccc1OCC(=O)O -US20100240656A1,3,C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc2c(cc1Br)OCO2>>C=Cc1cc2c(cc1Br)OCO2 -US20110071194A1,2,COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)N)c1.O=C(O)c1nc2ccccc2s1>>COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)NC(=O)c2nc3ccccc3s2)c1 -US20120094964A1,2,COC(=O)c1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(C(F)(F)F)cc1Cl>>COC(=O)c1ccc(S(=O)(=O)Nc2ccc(C(F)(F)F)cc2Cl)cc1 -US20090012081A1,1,COc1ccc(CCl)cc1.Cc1c(C)c2c(c(C)c1O)C(c1ccc(C(C)C)cc1)C(C)(C)O2>>COc1ccc(COc2c(C)c(C)c3c(c2C)C(c2ccc(C(C)C)cc2)C(C)(C)O3)cc1 -US20080085890A1,6,CCNCC1CCN(c2ccc(NC(=O)OC(C)(C)C)cc2)CC1>>CCNCC1CCN(c2ccc(N)cc2)CC1 -US20100069629A1,2,O=C(O)c1cc(Cl)ccn1.OCCN1CCNCC1>>O=C(c1cc(Cl)ccn1)N1CCN(CCO)CC1 -US20140155407A1,3,Brc1ccc(Cn2ccnc2)cn1.Nc1ccc(B(O)O)cc1>>Nc1ccc(-c2ccc(Cn3ccnc3)cn2)cc1 -US20100130446A1,4,CSc1ccc(C(C)(CC2CCOCC2)C(=O)CCC(=O)c2ccccn2)nc1.[NH4+]>>CSc1ccc(C(C)(CC2CCOCC2)c2ccc(-c3ccccn3)[nH]2)nc1 -US06043373,4,NC(N)=S.O=C1c2sc3nc4ccccc4n3c2CCC1Br>>Nc1nc2c(s1)CCc1c-2sc2nc3ccccc3n12 -US20070123504A1,2,Nc1ccc(N2CCSCC2)nc1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>O=C(Nc1ccc(N2CCSCC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US05283240,2,CN=C=O.NCCC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21>>CNC(=O)NCCC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 -US20090156578A1,2,CN[C@H](C)c1oc2ccccc2c1C.O=C(O)C=Cc1cnc2c(c1)CCC(=O)N2>>Cc1c([C@@H](C)N(C)C(=O)C=Cc2cnc3c(c2)CCC(=O)N3)oc2ccccc12 -US08101775B2,1,CC[C@@H](C)O.N#Cc1cc(C=O)ccc1F>>CC[C@@H](C)Oc1ccc(C=O)cc1C#N -US20080269220A1,6,Cc1cc(OCCN2CCCC2=O)cc(C)c1-c1cccc(CNc2ccc(CCC(=O)OC(C)(C)C)c(F)c2)c1>>Cc1cc(OCCN2CCCC2=O)cc(C)c1-c1cccc(CNc2ccc(CCC(=O)O)c(F)c2)c1 -US06046201,6,CC(C)(C)OC(=O)NCCCCCCCCCCCCOS(C)(=O)=O>>CS(=O)(=O)OCCCCCCCCCCCCN -US07943642B2,1,CCS.O=[N+]([O-])c1cc[nH]c1Cl>>CCSc1[nH]ccc1[N+](=O)[O-] -US04309345,1,CC(C)N.COc1ccc2c(c1)CCC1CCN(C)C(=O)C(CC(C)=O)=C21>>COc1ccc2c(c1)CCC1CCN(C)C(=O)C(CC(C)NC(C)C)=C21 -US20100069629A1,1,CN1CCN(CCCN)CC1.O=[N+]([O-])c1ccc(I)cc1>>CN1CCN(CCCNc2ccc([N+](=O)[O-])cc2)CC1 -US20060079533A1,10,Brc1ccc(C2=CCN(Cc3ccccc3)CC2)cc1.O>>OC1CN(Cc2ccccc2)CCC1c1ccc(Br)cc1 -US20130029962A1,2,Nc1ccc(N2CCC2)nc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(N2CCC2)nc1)Oc1ccccc1 -US04393210,1,O=c1[nH]cc(-c2ccccc2)c2ccccc12.OCCCCl>>O=c1c2ccccc2c(-c2ccccc2)cn1CCCO -US20110257151A1,6,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cc(OC)cc(N3CCOCC3)c1)N2>>COc1cc(C2Nc3ccc(C(=O)O)cc3CC2(C)C)cc(N2CCOCC2)c1 -US20040034017A1,1,ClCCCCBr.O=C1c2ccc(OC3CCCCO3)cc2OC(c2ccc(O)cc2)C1c1ccc(OC2CCCCO2)cc1>>O=C1c2ccc(OC3CCCCO3)cc2OC(c2ccc(OCCCCCl)cc2)C1c1ccc(OC2CCCCO2)cc1 -US08524897B2,2,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)CO[C@@]1(C)C(F)(F)F.Cc1cc(C#N)cnc1C(=O)O>>Cc1cc(C#N)cnc1C(=O)Nc1ccc(F)c([C@]2(C)CO[C@@](C)(C(F)(F)F)C(NC(=O)OC(C)(C)C)=N2)c1 -US20140364413A1,7,CC(C)(C)OC(=O)N1CC=C(c2c(CO)nc3c(N4CCOCC4)ccnn23)CC1>>CC(C)(C)OC(=O)N1CCC(c2c(CO)nc3c(N4CCOCC4)ccnn23)CC1 -US06310095B1,2,CCCS(=O)(=O)Cl.NCCC1CCCCC1>>CCCS(=O)(=O)NCCC1CCCCC1 -US08637670B2,2,CC(=O)[O-].CC(C)(C#N)c1ccc(-n2c(=O)[nH]c3cnc4ccc(Cl)cc4c32)cc1>>CC(=O)n1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(Cl)ccc3ncc21 -US04784471,8,N#Cc1ccc(CO)cc1F>>N#Cc1ccc(C=O)cc1F -US20040198755A1,6,COC(=O)c1cnc2c(c1)NC(=O)CS2>>O=C1CSc2ncc(C(=O)O)cc2N1 -US20040006141A1,6,CCCC(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)cc1)C(=O)OCC>>CCCC(Cc1ccc(OCCNC(=O)c2ccc(-c3ccccn3)cc2)cc1)C(=O)O -US20130244993A1,3,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O.O=c1ccccn1-c1nc(Br)cs1>>C[C@@H](c1ccc(-c2csc(-n3ccccc3=O)n2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O -US20060247439A1,1,CC(=O)c1ccsc1.NCCCNc1ccc2ccccc2n1>>CC(NCCCNc1ccc2ccccc2n1)c1ccsc1 -US07423030B2,1,CCNCC.COc1ccc2c(-c3ccc(CCl)cc3)nnc(Cl)c2c1>>CCN(CC)Cc1ccc(-c2nnc(Cl)c3cc(OC)ccc23)cc1 -US05856529,2,CCOC(=O)c1cccc(OCc2ccccc2)c1CCCO.CS(=O)(=O)Cl>>CCOC(=O)c1cccc(OCc2ccccc2)c1CCCOS(C)(=O)=O -US09085575B2,1,CCI.O=C(c1cc(F)cc(F)c1)c1ccc[nH]c1=O>>CCn1cccc(C(=O)c2cc(F)cc(F)c2)c1=O -US05087640,7,O=[N+]([O-])c1cc(F)cc(Br)c1>>Nc1cc(F)cc(Br)c1 -US20070037787A1,2,NCc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1.O=C(O)Cc1ccc(CNCC(O)C(O)C(O)C(O)CO)cc1>>O=C(Cc1ccc(CNCC(O)C(O)C(O)C(O)CO)cc1)NCc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1 -US20130109704A1,1,Cn1cnc2nc(Cl)nc(Cl)c21.NC1CCCCC1>>Cn1cnc2nc(Cl)nc(NC3CCCCC3)c21 -US07728025B2,2,CON(C)C(=O)c1ccc(N)cc1F.O=C(O)c1cnccn1>>CON(C)C(=O)c1ccc(NC(=O)c2cnccn2)cc1F -US20050014812A1,1,CCOc1ccc(Cn2c(C)nc3c(C)cc(CO)cc32)c(Cl)c1.COC(=O)c1cccc(O)c1>>CCOc1ccc(Cn2c(C)nc3c(C)cc(COc4cccc(C(=O)OC)c4)cc32)c(Cl)c1 -US20080176867A1,3,CC(=O)Cc1ccc(Br)cc1.O=Cc1ccc(Cl)cc1Cl>>CC(=O)C(=Cc1ccc(Cl)cc1Cl)c1ccc(Br)cc1 -US20150191481A1,7,Nc1ccc2c(=O)cc(-c3ccccc3)oc2c1[N+](=O)[O-]>>Nc1ccc2c(=O)cc(-c3ccccc3)oc2c1N -US06586447B1,1,CC(C)(C)OC(=O)C1(C(=O)OC(C)(C)C)C(=O)Nc2cc(Br)ccc21.CN(C)S(=O)(=O)c1ccc(CBr)cc1>>CN(C)S(=O)(=O)c1ccc(CN2C(=O)C(C(=O)OC(C)(C)C)(C(=O)OC(C)(C)C)c3ccc(Br)cc32)cc1 -US20080027049A1,2,CC(C)(C)c1ccc(C(=O)Cl)cc1.Nc1ccc2oc3c(c2c1)CCCCCC3>>CC(C)(C)c1ccc(C(=O)Nc2ccc3oc4c(c3c2)CCCCCC4)cc1 -US20110224208A1,2,COCCCN1C(=O)c2ccccc2C(C(=O)O)C1c1cccs1.COc1cccc(N)c1>>COCCCN1C(=O)c2ccccc2C(C(=O)Nc2cccc(OC)c2)C1c1cccs1 -US06087379,6,CC(O)C1CN(Cc2ccccc2)CCC1=O>>CC(O)C1CNCCC1=O -US07964591B2,2,O=C(Cl)c1cc(F)ccc1Cl.O=C(NCCC1CC1)c1ccc(N2CCNCC2)nn1>>O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3cc(F)ccc3Cl)CC2)nn1 -US20060258722A1,6,CCOC(=O)CCCCc1cccc(OC)c1>>COc1cccc(CCCCC(=O)O)c1 -US20060160838A1,6,CC(C)(C)[Si](C)(C)OCc1ccc(O[Si](C)(C)C(C)(C)C)cc1>>CC(C)(C)[Si](C)(C)OCc1ccc(O)cc1 -US20070191388A1,2,CCOC(=O)c1c(O)c2cccnc2n(Cc2ccccc2)c1=O.NC1CCCCC1>>O=C(NC1CCCCC1)c1c(O)c2cccnc2n(Cc2ccccc2)c1=O -US04069382,2,CC(=O)Cl.Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O>>CC(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H](O)[C@@H]1O -US06054407,4,C=CCCCCCC.OO>>CCCCCCC1CO1 -US20100125064A1,1,N#CCBr.c1ccc(CCN2CCNCC2)cc1>>N#CCN1CCN(CCc2ccccc2)CC1 -US05646171,1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CBr)cc1.CCCCc1nc(C(=O)c2ccccc2)c(C#N)[nH]1>>CCCCc1nc(C(=O)c2ccccc2)c(C#N)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1 -US07186730B2,2,CS(=O)(=O)Cl.O=c1[nH]c2cc(CCO)ccc2o1>>CS(=O)(=O)OCCc1ccc2oc(=O)[nH]c2c1 -US20110253931A1,2,CCCCCCCCCCOCC(O)CN1CCc2ccccc2C1.O=S(=O)(O)Cl>>CCCCCCCCCCOCC(CN1CCc2ccccc2C1)OS(=O)(=O)O -US20130045962A1,1,C=O.CC[C@@H]1CN(Cc2ccccc2)[C@H](C)CN1>>CC[C@@H]1CN(Cc2ccccc2)[C@H](C)CN1C -US05889021,1,CCC(=O)c1cnc2c(OCCSC)cccc2c1Cl.Cc1ccccc1N>>CCC(=O)c1cnc2c(OCCSC)cccc2c1Nc1ccccc1C -US20140171430A1,1,Cc1cc(C)nc(Cl)n1.O=C(c1ccccc1-c1cccs1)N1CC2CNCC2C1>>Cc1cc(C)nc(N2CC3CN(C(=O)c4ccccc4-c4cccs4)CC3C2)n1 -US20150225452A1,7,C[C@@H](C(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)N(C)C(=O)OC(C)(C)C>>C[C@@H](C(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)N(C)C(=O)OC(C)(C)C -US20070049618A1,2,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccc(F)cc1>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)c4ccc(F)cc4)c3C2=O)C(=O)N1 -US20140371203A1,9,Clc1nc(Cl)c2c(-c3ccccc3)csc2n1>>Clc1ncc2c(-c3ccccc3)csc2n1 -US20040192688A1,1,CCCCC(CC)CN.ClCCCOc1ccc2ccccc2c1>>CCCCC(CC)CNCCCOc1ccc2ccccc2c1 -US08383644B2,1,COC(=O)[C@H](Cc1ccc(OC(CO)c2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)c(Br)c1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc2c(c1)OCC(c1ccc(OCc3ccc(Cl)c(Cl)c3)cc1)O2)NC(=O)OC(C)(C)C -US07625909B2,3,C[Mg+].O=C1CN(C(c2ccccc2)c2ccccc2)C1>>CC1(O)CN(C(c2ccccc2)c2ccccc2)C1 -US05606089,7,CC(C)(C)c1cc2occc2c(C(C)(C)C)c1O>>CC(C)(C)c1cc2c(c(C(C)(C)C)c1O)CCO2 -US07524843B2,3,C=CC(=O)OCc1ccccc1.Nc1ccc(Br)cn1>>Nc1ccc(/C=C/C(=O)OCc2ccccc2)cn1 -US20100234351A1,1,COC(=O)CCCNCc1ccc(OC)cc1.O=Cc1c(Cl)ncnc1Cl>>COC(=O)CCCN(Cc1ccc(OC)cc1)c1ncnc(Cl)c1C=O -US20110053931A1,2,COc1ccc(C(=O)Cl)cc1F.c1ccc(CC2CCCNC2)cc1>>COc1ccc(C(=O)N2CCCC(Cc3ccccc3)C2)cc1F -US20120128630A1,1,CCOc1ccc(C2C(C(=O)c3ccc(C(C)C)cc3)=C(O)C(=O)N2c2ccc(C)nn2)cn1.COC(=O)[C@@H](O)c1ccccc1>>CCOc1ccc([C@H]2C(C(=O)c3ccc(C(C)C)cc3)=C(O[C@@H](C(=O)OC)c3ccccc3)C(=O)N2c2ccc(C)nn2)cn1 -US20100152240A1,7,CC(C)(C)OC(=O)c1cscc1C(=O)O>>CC(C)(C)OC(=O)c1cscc1CO -US20050043309A1,1,CC(C)(CCC=O)Oc1ccc2c(n1)NC(=O)CC2.Clc1cccc(N2CCNCC2)c1Cl>>CC(C)(CCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1ccc2c(n1)NC(=O)CC2 -US20150105366A1,3,COc1nc2ccc(C(=O)c3cncn3C)cc2c(Cl)c1Cc1ccc(S(C)(=O)=O)cc1.[Mg+]c1ccccn1>>COc1nc2ccc(C(O)(c3ccccn3)c3cncn3C)cc2c(Cl)c1Cc1ccc(S(C)(=O)=O)cc1 -US20050143452A1,2,CCc1cc(Br)c2c(c1)CC(CO)O2.Cc1ccc(S(=O)(=O)Cl)cc1>>CCc1cc(Br)c2c(c1)CC(COS(=O)(=O)c1ccc(C)cc1)O2 -US04748253,5,COc1ccc(C(=O)CBr)cc1.OCCO>>COc1ccc(C2(CBr)OCCO2)cc1 -US20120283256A1,1,Clc1ccc2c(Cl)ccnc2c1.Nc1ccc(CN2CCOCC2)c(O)c1>>Oc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1CN1CCOCC1 -US20140350019A1,1,CCOC(=O)CBr.Oc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2Cl)c1F>>CCOC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2Cl)c1F -US04443617,1,CC(C)(Br)[C@@H]1CC(=O)O[C@H]1O.C[C@H](O)c1cccc(Oc2ccccc2)c1>>CC(O[C@@H]1OC(=O)C[C@H]1C(C)(C)Br)c1cccc(Oc2ccccc2)c1 -US08143261B2,1,NCCOCCO.Nc1nc2nc(SCc3cccc(F)c3F)nc(Cl)c2s1>>Nc1nc2nc(SCc3cccc(F)c3F)nc(NCCOCCO)c2s1 -US08263629B2,6,CCOC(=O)Cc1nnc(CC)s1>>CCc1nnc(CC(=O)O)s1 -US08324176B2,2,CC(N)CC(=O)O.O=C(Cl)OCc1ccccc1>>CC(CC(=O)O)NC(=O)OCc1ccccc1 -US06844345B2,7,C[C@@H]1CNC(=O)c2cc3cccc(OC(F)(F)F)c3n21>>C[C@@H]1CNCc2cc3cccc(OC(F)(F)F)c3n21 -US07795283B2,7,CCOC(=O)C=C1CC[C@H](c2ccc(N)cc2)C1>>CCOC(=O)CC1CC[C@H](c2ccc(N)cc2)C1 -US04642308,2,COc1ccc2ccc(N)nc2n1.O=C(O)c1ccco1>>COc1ccc2ccc(NC(=O)c3ccco3)nc2n1 -US05358948,4,CCCCOc1ccccc1N.CN(CCCl)CCCl>>CCCCOc1ccccc1N1CCN(C)CC1 -US20100184809A1,1,CO.Cc1cc(Cl)ncc1[N+](=O)[O-]>>COc1cc(C)c([N+](=O)[O-])cn1 -US20090324581A1,6,CC(C)(C)OC(=O)N1CCc2cc(OCc3cn(C4CCCCC4)nc3C(F)(F)F)ccc21>>FC(F)(F)c1nn(C2CCCCC2)cc1COc1ccc2c(c1)CCN2 -US07408071B2,6,CC(C)(C)OC(=O)[C@H]1CCCN1c1ccc(C(F)(F)F)cc1>>O=C(O)[C@H]1CCCN1c1ccc(C(F)(F)F)cc1 -US08455477B2,6,CCOC(=O)c1cnn2cc(-c3cnn(C)c3)cc(OC)c12>>COc1cc(-c2cnn(C)c2)cn2ncc(C(=O)O)c12 -US07649001B2,1,N#Cc1ccc(F)c2ccccc12.c1ccc2c(c1)CCNC2>>N#Cc1ccc(N2CCc3ccccc3C2)c2ccccc12 -US20130216498A1,1,CNCc1ccccc1.Clc1ccnc(Cl)n1>>CN(Cc1ccccc1)c1ccnc(Cl)n1 -US20140128401A1,7,Cn1cc(-c2ccnc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2C=O)cc(Nc2cc3n(n2)CCN(CC(F)(F)F)C3)c1=O>>Cn1cc(-c2ccnc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2CO)cc(Nc2cc3n(n2)CCN(CC(F)(F)F)C3)c1=O -US20070082931A1,4,NC(=S)c1cn(CC2CCCCC2)c2c(Cl)cccc12.O=C(CCl)CCl>>ClCc1csc(-c2cn(CC3CCCCC3)c3c(Cl)cccc23)n1 -US20030207865A1,6,CC(=O)Nc1ccc([N+](=O)[O-])c2c1CCCC2>>Nc1ccc([N+](=O)[O-])c2c1CCCC2 -US20020193367A1,2,COCCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl.Cc1cc(-c2cc(C(=O)CC(=O)OC(C)(C)C)ccn2)on1>>COCCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2ccnc(-c3cc(C)no3)c2)cc1Cl -US20090012063A1,7,CCCCCCc1cccc(-c2nc(C#CCOC)c(C(=O)N3CCC(N4CCCC4)CC3)n2C)c1>>CCCCCCc1cccc(-c2nc(CCCOC)c(C(=O)N3CCC(N4CCCC4)CC3)n2C)c1 -US08952004B2,2,CCOC(=O)CC1CCN(c2ccccc2N)CC1.O=C(Cl)c1cccc(Cl)c1>>CCOC(=O)CC1CCN(c2ccccc2NC(=O)c2cccc(Cl)c2)CC1 -US20080090846A1,1,O=C(NCc1ccc(CNC2CCCc3cccnc32)cc1)c1ccccn1.O=Cc1nc2ccccc2[nH]1>>O=C(NCc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1)c1ccccn1 -US20070185136A1,4,COc1ccc(S(=O)(=O)N(CC#N)c2ccc(Cl)cc2Cc2c(F)cccc2F)cc1OC.C[Si](C)(C)N=[N+]=[N-]>>COc1ccc(S(=O)(=O)N(Cc2nnn[nH]2)c2ccc(Cl)cc2Cc2c(F)cccc2F)cc1OC -US20040259917A1,3,Brc1cn(-c2ccccn2)cn1.OB(O)c1cccc(Cl)c1>>Clc1cccc(-c2cn(-c3ccccn3)cn2)c1 -US20120302566A1,3,CC(C)c1ccccc1B(O)O.O[C@H]1CCc2cc(Br)ccc21>>CC(C)c1ccccc1-c1ccc2c(c1)CC[C@@H]2O -US20140213587A1,7,O=Cc1ccc(-c2ccccc2)c(F)c1>>OCc1ccc(-c2ccccc2)c(F)c1 -US20030072964A1,3,Clc1ccc2ccccc2n1.OB(O)c1ccc(F)cc1F>>Fc1ccc(-c2ccc3ccccc3n2)c(F)c1 -US07960380B2,6,CC(C)(C)OC(=O)NCCC(=O)Oc1ccc(OC(F)(F)F)cc1>>NCCC(=O)Oc1ccc(OC(F)(F)F)cc1 -US08044242B2,5,NCc1ccccc1SC1CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCc1ccccc1SC1CC1)C(F)(F)F -US20110076291A1,1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.ClCCBr>>CC1(C)OB(c2cnn(CCCl)c2)OC1(C)C -US20090156572A1,2,CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1.COC(=O)N1CCC(C(=O)O)CC1>>COC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3ccc(Cl)cc3)[C@H](c3ccc(Cl)c(Cl)c3)C2)CC1 -US20100004222A1,2,Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)O.Nc1cnc2ncccc2c1>>Cc1cc(/C=C/C(F)(F)F)ccc1C(=O)Nc1cnc2ncccc2c1 -US06750218B2,2,COc1cc2ncnc(N3CCNCC3)c2cc1OC.O=C(Cl)N(c1ccccc1)c1ccccc1>>COc1cc2ncnc(N3CCN(C(=O)N(c4ccccc4)c4ccccc4)CC3)c2cc1OC -US04997943,5,COc1c(N)ccc(F)c1F.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1c(NC(=O)C(F)(F)F)ccc(F)c1F -US20030139418A1,1,CC(C)(C)OC(=O)c1ccc(NCc2cc(Br)ccc2OCc2ccccc2)cc1.COC(=O)c1ccc(CBr)cc1>>COC(=O)c1ccc(CN(Cc2cc(Br)ccc2OCc2ccccc2)c2ccc(C(=O)OC(C)(C)C)cc2)cc1 -US20030166628A1,7,O=CC1=C(c2cccc3sccc23)N2CCN=C2S1>>OCC1=C(c2cccc3sccc23)N2CCN=C2S1 -US20090221584A1,1,CCNS(=O)(=O)c1ccc(I)cc1.COc1ccc(CS)cc1>>CCNS(=O)(=O)c1ccc(SCc2ccc(OC)cc2)cc1 -US20050203064A1,1,O=S(CCn1ccnn1)Cc1ccc(O)cc1.O=S(c1ccc(C=Cc2nc(CCl)co2)cc1)C(F)(F)F>>O=S(CCn1ccnn1)Cc1ccc(OCc2coc(/C=C/c3ccc(S(=O)C(F)(F)F)cc3)n2)cc1 -US07528136B2,1,COC(=O)C1CC(O)CN1.ClCc1ccc(Cl)c(Cl)c1>>COC(=O)[C@@H]1C[C@@H](O)CN1Cc1ccc(Cl)c(Cl)c1 -US20140206681A1,6,COC(=O)C1CCC2CCC(=O)N2C1>>O=C(O)[C@H]1CC[C@H]2CCC(=O)N2C1 -US08314100B2,2,CCOC(=O)Nc1nc2cc(C)ccc2nc1OC.Fc1ccccc1N1CCNCC1>>COc1nc2ccc(C)cc2nc1NC(=O)N1CCN(c2ccccc2F)CC1 -US20020028836A1,8,CC(C)(CO)C1CCCCC1>>CC(C)(C=O)C1CCCCC1 -US08288566B2,2,CC/C(=C\C(C)O)C(N)=O.O=C(Cl)CCl>>CC/C(=C\C(C)OC(=O)CCl)C(N)=O -US07622471B2,4,CCOC(=O)C(=O)CC(=O)c1cccc(C)c1.COc1ccc(NN)cn1>>CCOC(=O)c1cc(-c2cccc(C)c2)n(-c2ccc(OC)nc2)n1 -US08173646B2,2,CNCc1cn(Cc2ccccc2)c2ccccc12.Nc1ccc(C=CC(=O)O)cn1>>CN(Cc1cn(Cc2ccccc2)c2ccccc12)C(=O)/C=C/c1ccc(N)nc1 -US20040053928A1,1,NCC(=O)OCc1ccccc1.O=C1CCN(Cc2ccccc2)CC1>>O=C(CNC1CCN(Cc2ccccc2)CC1)OCc1ccccc1 -US20100004235A1,1,Fc1cccc(CBr)c1F.N#Cc1n[nH]c2ncccc12>>N#Cc1nn(Cc2cccc(F)c2F)c2ncccc12 -US20120039804A1,2,C1CCNCC1.O=C(O)c1ccc2[nH]c3ccccc3c2c1>>O=C(c1ccc2[nH]c3ccccc3c2c1)N1CCCCC1 -USRE039679E1,7,COC(=O)CCc1cn(C)c2ccccc12>>Cn1cc(CCCO)c2ccccc21 -US20070003680A1,6,CCOC(=O)C(C)(C)c1ccc(-c2cccc(COC)c2)c(OC)c1>>COCc1cccc(-c2ccc(C(C)(C)C(=O)O)cc2OC)c1 -US20040034041A1,2,CCOC(=O)c1c(O)c2ccccc2n(Cc2ccccn2)c1=O.Nc1ccccc1S(N)(=O)=O>>NS(=O)(=O)c1ccccc1NC(=O)c1c(O)c2ccccc2n(Cc2ccccn2)c1=O -US07030141B2,2,CO[C@@H]1C[C@H](C(=O)O)N(C(=O)OC(C)(C)C)C1.Cc1ccn(-c2ccc(N)c(F)c2)n1>>CO[C@@H]1C[C@H](C(=O)Nc2ccc(-n3ccc(C)n3)cc2F)N(C(=O)OC(C)(C)C)C1 -US08106215B2,2,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(C)C[C@@H]3[C@H]2CN)c1.O=C(O)c1cccc(Cl)c1>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(C)C[C@@H]3[C@H]2CNC(=O)c2cccc(Cl)c2)c1 -US06552225B1,2,C[C@@](O)(C(=O)O)C(F)(F)F.Nc1cccc([N+](=O)[O-])c1Cl>>C[C@@](O)(C(=O)Nc1cccc([N+](=O)[O-])c1Cl)C(F)(F)F -US20140243322A1,6,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCNC(=O)OC(C)(C)C)c1nnc(C)n1-2>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN)c1nnc(C)n1-2 -US20090048291A1,6,COC(=O)CC1CCN(CCN(c2ccccc2)c2ccccc2)CC1>>O=C(O)CC1CCN(CCN(c2ccccc2)c2ccccc2)CC1 -US05532237,2,Cc1[nH]c2ccccc2c1C=O.O=C(Cl)c1cccc2ccccc12>>Cc1c(C=O)c2ccccc2n1C(=O)c1cccc2ccccc12 -US05061703,9,CC12CC3CC(C)(C1)CC(CCBr)(C3)C2>>CCC12CC3CC(C)(CC(C)(C3)C1)C2 -US20100004221A1,3,CCOC(=O)c1cc(Br)ccc1Cl.OB(O)c1ccc(F)cc1>>CCOC(=O)c1cc(-c2ccc(F)cc2)ccc1Cl -US09156827B2,6,CN(CCCCCCCCN(C)C(=O)OC(C)(C)C)Cc1c(O)ccc2c1O/C(=C\c1c[nH]c3ccccc13)C2=O>>CNCCCCCCCCN(C)Cc1c(O)ccc2c1O/C(=C\c1c[nH]c3ccccc13)C2=O -US04518713,2,CCc1ccc(OC2CCNCC2)cc1.O=C(Br)CBr>>CCc1ccc(OC2CCN(C(=O)CBr)CC2)cc1 -US06162824,3,CC(C)(C)[Mg+].O=C1c2ccccc2-c2ccccc21>>CC(C)(C)C1(O)c2ccccc2-c2ccccc21 -US20110245224A1,9,CCOC(=O)c1noc2c(F)c(N3C[C@H](C)O[C@H](C)C3)c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc12.[NH4+]>>C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc3c(C(N)=O)noc3c2F)C[C@@H](C)O1 -US05441971,6,COCOCc1ccc(CCOc2ccc([N+](=O)[O-])cc2)nc1>>O=[N+]([O-])c1ccc(OCCc2ccc(CO)cn2)cc1 -US05254724,6,COCCOCCOCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCN(OCc1ccccc1)C(=O)OC(C)(C)C>>COCCOCCOCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCNOCc1ccccc1 -US20130109661A1,1,C1CCNCC1.Nc1cccc(F)n1>>Nc1cccc(N2CCCCC2)n1 -US09096600B2,3,COc1c(C(C)Nc2ncnc3c2ncn3C2CCCCO2)cc(Cl)c(C)c1Br.Cn1cc(B2OC(C)(C)C(C)(C)O2)cc1C(=O)OCc1ccccc1>>COc1c(C(C)Nc2ncnc3c2ncn3C2CCCCO2)cc(Cl)c(C)c1-c1cc(C(=O)OCc2ccccc2)n(C)c1 -US20150018363A1,1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1csc(Br)c1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4csc(Br)c4)cc3=O)cc21 -US05451394,1,CCCCCCCCCCCCCCCCCCCl.CN(C)CCCNC(=O)c1ccc(N(C)C)cc1>>CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCNC(=O)c1ccc(N(C)C)cc1 -US20040006141A1,9,CCOC(=O)C(C)(Cc1ccc(OCCN=[N+]=[N-])cc1)Oc1ccccc1>>CCOC(=O)C(C)(Cc1ccc(OCCN)cc1)Oc1ccccc1 -US20130109661A1,1,COC(=O)c1cccc(-c2cc(Br)c3nccn3n2)c1.Nc1cccc(N2CCCC2CO)n1>>COC(=O)c1cccc(-c2cc(Nc3cccc(N4CCCC4CO)n3)c3nccn3n2)c1 -US20100120672A1,6,COCCC1(COC)CCN(C(=O)OC(C)(C)C)CC1>>COCCC1(COC)CCNCC1 -US08293768B2,1,CCOC(=O)c1sc(-n2cn[nH]c2=O)cc1C.CS(=O)(=O)c1ccc(CBr)cc1>>CCOC(=O)c1sc(-n2cnn(Cc3ccc(S(C)(=O)=O)cc3)c2=O)cc1C -US06218385B1,1,Cc1nc(O)c([N+](=O)[O-])c(N2CCc3ccccc3CC2)n1.ClCCCc1ccccc1>>Cc1nc(OCCCc2ccccc2)c([N+](=O)[O-])c(N2CCc3ccccc3CC2)n1 -US08288549B2,1,O=C(O)c1cc2cc(Br)ccc2nc1NC(Cc1ccc(O)cc1)C(=O)O.O=C(O)c1cc2ccccc2nc1Cl>>O=C(O)c1cc2cc(Br)ccc2nc1NC(Cc1ccc(Oc2nc3ccccc3cc2C(=O)O)cc1)C(=O)O -US06399603B1,1,Nc1ccc(F)c(C(F)(F)F)c1.O=C(Nc1ccc(F)cc1)c1cc([N+](=O)[O-])cc2c(O)nc(Cl)nc12>>O=C(Nc1ccc(F)cc1)c1cc([N+](=O)[O-])cc2c(O)nc(Nc3ccc(F)c(C(F)(F)F)c3)nc12 -US08426585B2,1,CN1[C@H](COS(C)(=O)=O)CCC12CC2.Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C>>Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OC[C@@H]5CCC6(CC6)N5C)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C -US08153626B2,2,FC(F)(F)c1ccc2c(n1)Nc1ccc(I)cc1NC2.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1Cc2ccc(C(F)(F)F)nc2Nc2ccc(I)cc21 -US20110280812A1,2,C#CC#CCC/C=C/C=C/C(=O)O.NCCc1ccccc1>>C#CC#CCC/C=C/C=C/C(=O)NCCc1ccccc1 -US08828902B2,3,CC(=O)c1ccc(B(O)O)cc1.COc1ccc(Br)cc1>>COc1ccc(-c2ccc(C(C)=O)cc2)cc1 -US08981084B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1CNCCN1>>CC(C)(C)OC(=O)N1CCNC(C(=O)O)C1 -US20100035862A1,2,CN1CC(N)C1.O=C(O)c1cc2c(Cl)cc(Cl)cc2[nH]1>>CN1CC(NC(=O)c2cc3c(Cl)cc(Cl)cc3[nH]2)C1 -US08022099B2,9,CN(Cc1ccc(C(F)(F)F)c(F)c1)C1CN(C(=O)CCCCBr)CC1c1ccc(Cl)c(Cl)c1.[C-]#N>>CN(Cc1ccc(C(F)(F)F)c(F)c1)C1CN(C(=O)CCCCC#N)CC1c1ccc(Cl)c(Cl)c1 -US07271266B2,2,NN1CCCCC1.O=C(Cl)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Cl>>O=C(NN1CCCCC1)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Cl -US03978127,8,Cc1ccc(C(O)C(=O)c2ccc(Br)cc2)cc1>>Cc1ccc(C(=O)C(=O)c2ccc(Br)cc2)cc1 -US20060270637A1,2,CNCCCCCC(=O)O.COC(=O)Cl>>COC(=O)N(C)CCCCCC(=O)O -US06384051B1,7,COc1cc([N+](=O)[O-])cc2c(Nc3ccc(C)c(O)c3)c(C#N)cnc12>>COc1cc(N)cc2c(Nc3ccc(C)c(O)c3)c(C#N)cnc12 -US20130172302A1,1,O=C(CCl)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(c1ccccc1)N1CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(c1ccccc1)N1CCCCCC1)C2)c1ccccc1 -US04621901,1,C=CCCC[C@@H]1CC[C@@H](C(=O)O)CC1.CCOc1ccc(O)cc1>>C=CCCC[C@@H]1CC[C@@H](C(=O)Oc2ccc(OCC)cc2)CC1 -US05635510,6,O=C1NC(=O)C2(CCN(Cc3ccccc3)CC2)N1c1ccc(F)cc1>>O=C1NC(=O)C2(CCNCC2)N1c1ccc(F)cc1 -US04563446,3,CCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(c1ccccc1)c1cccnc1>>CCCCCC=C(c1ccccc1)c1cccnc1 -US05869501,2,CC(C)(C)OC(=O)N1CCC(Oc2ccc(NCc3ccc4ccc(C#N)cc4c3)cc2)CC1.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)N(Cc2ccc3ccc(C#N)cc3c2)c2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)cc2)c1 -US20120040954A1,10,COC(=O)c1cc(C)ccc1[N+](=O)[O-].O=C1CCC(=O)N1Br>>COC(=O)c1cc(CBr)ccc1[N+](=O)[O-] -US20060074240A1,6,Cc1ccc2c3c(ccc2n1)OCC(COCc1ccccc1)O3>>Cc1ccc2c3c(ccc2n1)OC[C@@H](CO)O3 -US08497281B2,2,O=C(O)c1ccc2nccn2c1.c1ccc2c(c1)CC[C@@H]1NCCC[C@H]21>>O=C(c1ccc2nccn2c1)N1CCC[C@@H]2c3ccccc3CC[C@@H]21 -US20080255114A1,2,C[C@H]1CN(Cc2ccccc2)C(=O)[C@H](C)N1c1nc2c(C(=O)O)cccc2o1.N[C@@H]1CN2CCC1CC2>>C[C@H]1CN(Cc2ccccc2)C(=O)[C@H](C)N1c1nc2c(C(=O)N[C@@H]3CN4CCC3CC4)cccc2o1 -US20050131014A1,1,BrCc1ccc2ccccc2n1.O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(O)c1>>O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(OCc2ccc3ccccc3n2)c1 -US08492378B2,2,C1COCCN1.Cc1nnc(-c2ccc3occ(-c4ccc(C(=O)O)c(F)c4)c3c2)o1>>Cc1nnc(-c2ccc3occ(-c4ccc(C(=O)N5CCOCC5)c(F)c4)c3c2)o1 -US20120252758A1,1,BrCCBr.Oc1ccccc1Br>>BrCCOc1ccccc1Br -US20150175567A1,6,COC(=O)COc1cccc(N(C(C)=O)C2CCc3ccc(-c4cccc(F)c4)cc32)c1>>CC(=O)N(c1cccc(OCC(=O)O)c1)C1CCc2ccc(-c3cccc(F)c3)cc21 -US08754068B2,7,C=C(C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>CC(C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US08481542B2,6,CCOC(=O)C1(C)CCN(c2nnc(Cc3ccccc3)c(C)c2C)CC1>>Cc1c(Cc2ccccc2)nnc(N2CCC(C)(C(=O)O)CC2)c1C -US20130303551A1,6,CCOC(=O)c1cnn(C)c1NC(=O)c1ccc(Br)cc1>>Cn1ncc(C(=O)O)c1NC(=O)c1ccc(Br)cc1 -US20150004181A1,6,CN1CCC(OC(c2cccc(C#C[Si](C)(C)C)c2)c2nc3ccccc3[nH]2)CC1>>C#Cc1cccc(C(OC2CCN(C)CC2)c2nc3ccccc3[nH]2)c1 -US07157464B2,1,CCOC(=O)c1[nH]nc(C)c1Cl.O=C(CCl)N1CCN(c2ccc(F)cc2)CC1>>CCOC(=O)c1c(Cl)c(C)nn1CC(=O)N1CCN(c2ccc(F)cc2)CC1 -US20070123527A1,7,CCOC(=O)C=C(c1ccccc1)c1cc2[nH]ccc2cc1OC>>CCOC(=O)CC(c1ccccc1)c1cc2[nH]ccc2cc1OC -US20100249123A1,2,COc1ccc(C(=O)Nc2ccc(C(C)(C)CN)cc2)cc1OC.COc1ccccc1C(=O)O>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CNC(=O)c3ccccc3OC)cc2)cc1OC -US20130252938A1,7,COC(=O)c1ncc(Br)cn1>>OCc1ncc(Br)cn1 -US20110046134A1,2,NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1.O=Cc1ccc(C(=O)O)cc1>>O=Cc1ccc(C(=O)NCC(=O)N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1 -US20120149721A1,2,CC(=O)Cl.CCc1ccc(OCC2CC2)c(-c2ncnc3c(C(=O)N[C@@H]4CNC[C@H]4O)c(C)[nH]c23)c1>>CCc1ccc(OCC2CC2)c(-c2ncnc3c(C(=O)N[C@@H]4CN(C(C)=O)C[C@H]4O)c(C)[nH]c23)c1 -US05932601,1,COc1cc(CCCC2OC(=O)NC2=O)ccc1O.Cc1sc(-c2ccccc2)nc1CCl>>COc1cc(CCCC2OC(=O)NC2=O)ccc1OCc1nc(-c2ccccc2)sc1C -US20090233937A1,2,CC(C)(O)C(=O)O.NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21>>CC(C)(O)C(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21 -US20130217666A1,3,C#CC(C)(C)O.NC(=O)c1nc2n(c1C1CC1)C1CC(C1)c1cc(F)c(Br)cc1-2>>CC(C)(O)C#Cc1cc2c(cc1F)C1CC(C1)n1c-2nc(C(N)=O)c1C1CC1 -US20150284383A1,6,COC(=O)c1cc(N[C@@H](C)C(N)=O)nc(Cl)n1>>C[C@H](Nc1cc(C(=O)O)nc(Cl)n1)C(N)=O -US06248739B1,1,Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)ccc21.FC1(F)CCNCC1>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCC(F)(F)CC3)ccc21 -US08445407B2,4,C#CCN1C(=O)C(F)(F)Oc2cc(F)c(N)cc21.O=C1OC(=O)C2=C1CCCC2>>C#CCN1C(=O)C(F)(F)Oc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21 -US08569522B2,1,CCOC(=O)C1CCOc2cc(O)c(Cl)cc21.Cc1cc(C(=O)NCCc2ccc(Cl)cc2)ccc1Br>>CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)NCCc4ccc(Cl)cc4)cc3C)c(Cl)cc21 -US04588727,2,CC(C)(C)OC(=O)NCC(=O)O.Nn1cccc1C(=O)c1ccccc1F>>CC(C)(C)OC(=O)NCC(=O)Nn1cccc1C(=O)c1ccccc1F -US20120277208A1,6,COC(=O)c1cc(OCc2ccccc2)cc(N(CC2CC2)C(C)=O)c1>>COC(=O)c1cc(O)cc(N(CC2CC2)C(C)=O)c1 -US05773612,2,COc1cc([N+](=O)[O-])ccc1S(=O)(=O)Cl.NC1(c2ccccc2Cl)C(=O)Nc2ccc(Cl)cc21>>COc1cc([N+](=O)[O-])ccc1S(=O)(=O)N1C(=O)C(N)(c2ccccc2Cl)c2cc(Cl)ccc21 -US20140140956A1,3,CC(C)(C)[Si](C)(C)OCCOc1ccc(C=O)nc1Br.CS(=O)c1cccc(B(O)O)c1>>CS(=O)c1cccc(-c2nc(C=O)ccc2OCCO[Si](C)(C)C(C)(C)C)c1 -US20120232074A1,7,COc1ccc([N+](=O)[O-])cc1-c1c(C)noc1C>>COc1ccc(N)cc1-c1c(C)noc1C -US20080194826A1,8,COC(=O)c1cc(OCCC2(CCO)CCCCC2)cc(C(=O)OC)c1>>COC(=O)c1cc(OCCC2(CC=O)CCCCC2)cc(C(=O)OC)c1 -US20030045546A1,4,N=C(N)c1ccc(Cl)cc1.O=C(CBr)c1sccc1Cl>>Clc1ccc(-c2ncc(-c3sccc3Cl)[nH]2)cc1 -US04380678,7,O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO -US20130197037A1,9,Cc1cc(F)c(Br)cc1N.N#C[Cu]>>Cc1cc(F)c(C#N)cc1N -US20110021514A1,2,COc1ccc2c(c1)CCC(C(=O)O)C2.Cc1cc(C(C)N)c(F)cc1NS(C)(=O)=O>>COc1ccc2c(c1)CCC(C(=O)NC(C)c1cc(C)c(NS(C)(=O)=O)cc1F)C2 -US05243076,1,BrCCCCCCBr.COc1ccccc1CCCCO>>COc1ccccc1CCCCOCCCCCCBr -US20040072842A1,6,CC(C)(C)OC(=O)NC[C@H]1CN(c2ccc(C3CCN(C(=O)CO)CC3)c(F)c2)C(=O)O1>>NC[C@H]1CN(c2ccc(C3CCN(C(=O)CO)CC3)c(F)c2)C(=O)O1 -US20140303156A1,2,Nc1cc(Cl)c(F)c(Cl)c1.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cc(Cl)c(F)c(Cl)c1 -US20090181948A1,1,C#CC(C)(C)Cl.N#CC(C#N)=C1N(CCCN2CCCCC2)CCN1C1CCNCC1>>C#CC(C)(C)N1CCC(N2CCN(CCCN3CCCCC3)C2=C(C#N)C#N)CC1 -US20140113935A1,2,CNCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.Cc1ccc(N=C=O)cc1Cl>>Cc1ccc(NC(=O)N(C)Cc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1Cl -US08202513B2,1,BrCCCBr.COc1c(Cl)c(C)c(C(C)=O)c(O)c1OCCC(C)c1ccc(F)cc1>>COc1c(Cl)c(C)c(C(C)=O)c(OCCCBr)c1OCCC(C)c1ccc(F)cc1 -US04952574,1,CCOCCBr.O=C(NCc1ccccn1)c1cc(OCC(F)(F)F)ccc1O>>CCOCCOc1ccc(OCC(F)(F)F)cc1C(=O)NCc1ccccn1 -US07282511B2,3,CN1CCc2c(Br)ccc([N+](=O)[O-])c2C1.OB(O)c1ccc(Cl)cc1>>CN1CCc2c(-c3ccc(Cl)cc3)ccc([N+](=O)[O-])c2C1 -US20090093456A1,3,C#C[Si](C)(C)C.COC(=O)c1sc(-c2ccc(Cl)cc2)cc1Br>>COC(=O)c1sc(-c2ccc(Cl)cc2)cc1C#C[Si](C)(C)C -US20080015191A1,1,Clc1cncc(Cl)n1.O=C1CCc2cccc(O)c21>>O=C1CCc2cccc(Oc3cncc(Cl)n3)c21 -US20090118254A1,1,O=C(c1ccc(O)cc1)N1CCC[C@H]1CN1CCCC1.OCc1cnccn1>>O=C(c1ccc(OCc2cnccn2)cc1)N1CCC[C@H]1CN1CCCC1 -US08293768B2,1,CCOC(=O)c1sc(N2CCNC2=O)nc1C.OCc1ccc(C(F)F)o1>>CCOC(=O)c1sc(N2CCN(Cc3ccc(C(F)F)o3)C2=O)nc1C -US20070072792A1,1,C=CCCCNS(=O)(=O)CCC(=O)OC.CI>>C=CCCCN(C)S(=O)(=O)CCC(=O)OC -US20080255114A1,2,CC(C)(C)OC(=O)N1CCN(c2nc3c(C(=O)O)cccc3o2)CC1.N[C@@H]1CN2CCC1CC2>>CC(C)(C)OC(=O)N1CCN(c2nc3c(C(=O)NC4CN5CCC4CC5)cccc3o2)CC1 -US20130292665A1,3,Brc1c2ccccc2cc2ccccc12.OB(O)c1ccc2c3ccccc3c3ccccc3c2c1>>c1ccc2c(-c3ccc4c5ccccc5c5ccccc5c4c3)c3ccccc3cc2c1 -US20120040954A1,3,C#CCCOC1CCCCO1.COC(=O)c1ccc(NC(C)=O)c(I)c1>>COC(=O)c1ccc(NC(C)=O)c(C#CCCOC2CCCCO2)c1 -US08173650B2,6,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2S(C)(=O)=O>>CS(=O)(=O)N1C[C@@H]2C[C@H]1CN2 -US20050148627A1,7,CCOC(=O)C1=Cc2ccc(C(C)(C)C=O)cc2OC1C(F)(F)F>>CCOC(=O)C1=Cc2ccc(C(C)(C)CO)cc2OC1C(F)(F)F -US08217043B2,1,CCOC(=O)c1cc2ccccc2n1N.O=Cc1ccc(F)cc1>>CCOC(=O)c1cc2ccccc2n1N=Cc1ccc(F)cc1 -US20150133544A1,1,CC(=O)N[C@@H](CS)C(=O)O.Cc1ccc(C(=O)Cl)cc1>>CC(=O)NC(CSC(=O)c1ccc(C)cc1)C(=O)O -US20040029950A1,1,Cc1ccc2[nH]cc(CCN)c2c1.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>Cc1ccc2[nH]cc(CCNc3ccc([N+](=O)[O-])cc3[N+](=O)[O-])c2c1 -US20100280067A1,2,CC(=O)NC(C)c1ccc2c(c1)CCNC2.O=C(O)c1ccc(OCC2CC2)cc1>>CC(=O)NC(C)c1ccc2c(c1)CCN(C(=O)c1ccc(OCC3CC3)cc1)C2 -US06982348B2,2,NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1F.O=C(O)c1ccc(F)c2ccccc12>>O=C(NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1F)c1ccc(F)c2ccccc12 -US20110003787A1,2,COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C(=O)O)[nH]2)c1.NC[C@H](O)CO>>COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C(=O)NC[C@H](O)CO)[nH]2)c1 -US20130079320A1,2,CC(C(=O)O)c1cccc(C#N)c1.NCc1ccc(C(F)(F)F)nc1N1CCCC1>>CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCC1)c1cccc(C#N)c1 -US20060106066A1,6,CCCN1CCC(N(Cc2cccc(OC)c2)c2ccc(C(=O)N(CC)CC)cc2)CC1>>CCCN1CCC(N(Cc2cccc(O)c2)c2ccc(C(=O)N(CC)CC)cc2)CC1 -US20080153850A1,1,COC(=O)[C@@H](C)Cl.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(-c2ccc(O)cc2)ccc1Cl>>COC(=O)[C@H](C)Oc1ccc(-c2ccc(Cl)c(C(=O)NCC34CC5CC(CC(C5)C3)C4)c2)cc1 -US06392059B1,3,CO[C@H]1O[C@@H](C)[C@@H]2C(=O)[C@H]3CCCC[C@@H]3C[C@@H]21.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1[C@@H]2[C@H](C[C@H]3CCCC[C@H]13)[C@@H](OC)O[C@H]2C -US20040072842A1,6,O=C(NC[C@H]1CN(c2ccc(N3CCN(C(=O)OCc4ccccc4)CC3)c(F)c2)C(=O)O1)C(F)F>>O=C(NC[C@H]1CN(c2ccc(N3CCNCC3)c(F)c2)C(=O)O1)C(F)F -US04424231,6,C=CCc1c(OCCCOc2ccc(C(C)=O)c(O)c2CCC)ccc2oc(C(=O)OC)cc12>>C=CCc1c(OCCCOc2ccc(C(C)=O)c(O)c2CCC)ccc2oc(C(=O)O)cc12 -US20100168418A1,6,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3cc(N)ccc32)CC1>>Nc1ccc2c(ccc(=O)n2CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c1 -US05763450,6,CCOC(=O)c1cn(C2CC2)c2c(F)c(C#Cc3cc(Cc4cnc(N)nc4N)cc(OC)c3OC)c(F)cc2c1=O>>COc1cc(Cc2cnc(N)nc2N)cc(C#Cc2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)c1OC -US20110136763A1,6,CCOC(=O)CC1OB(O)c2cc(Oc3ncc(C(=O)OC(C)(C)C)s3)cc(C)c21>>CCOC(=O)CC1OB(O)c2cc(Oc3ncc(C(=O)O)s3)cc(C)c21 -US05496927,2,C[C@H](N)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1 -US04778805,7,COc1ccc(C(=O)c2oc3c(O)c(C)c(C)cc3c2C)cc1>>COc1ccc(Cc2oc3c(O)c(C)c(C)cc3c2C)cc1 -US08022206B2,2,CC(C)N=C=O.C[C@@H](Oc1c(N)ncc2c(C3=CCNCC3)coc12)c1c(Cl)ccc(F)c1Cl>>CC(C)NC(=O)N1CC=C(c2coc3c(O[C@H](C)c4c(Cl)ccc(F)c4Cl)c(N)ncc23)CC1 -US20130190330A1,1,Clc1cccc(-c2cc(CBr)ccn2)c1Cl.O=c1[nH]nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F>>O=c1n(Cc2ccnc(-c3cccc(Cl)c3Cl)c2)nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F -US08921389B2,2,COC(=O)c1ncc2c(ccc(=O)n2Cc2ccccc2)c1O.NCCC(=O)O>>O=C(O)CCNC(=O)c1ncc2c(ccc(=O)n2Cc2ccccc2)c1O -US07754886B2,1,C1CC2(CCN1)OCCO2.CCOC(=O)c1ccc(F)cc1>>CCOC(=O)c1ccc(N2CCC3(CC2)OCCO3)cc1 -US05202324,1,C[C@H](CO)CS(N)(=O)=O.Clc1ccc2nccn2n1>>C[C@H](COc1ccc2nccn2n1)CS(N)(=O)=O -US04888439,9,CC(=O)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C(=O)O.N>>CC(=O)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C(N)=O -US20140107093A1,7,CC(C)S(=O)(=O)c1ccc(-c2cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(-c3cc(-c4ccc([N+](=O)[O-])cc4)no3)n2)cc1>>CC(C)S(=O)(=O)c1ccc(-c2cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(-c3cc(-c4ccc(N)cc4)no3)n2)cc1 -US20140107343A1,9,NC(=O)c1ccc2c(c1)C1CCCNC1C2>>N#Cc1ccc2c(c1)C1CCCNC1C2 -US20050090669A1,1,CC(C)(C)OC(=O)N(C[C@H](O)c1cccc(Cl)c1)[C@H]1CCc2ccc(Oc3ccc(F)c(C=O)c3)cc2C1.Oc1ccccc1>>CC(C)(C)OC(=O)N(C[C@H](O)c1cccc(Cl)c1)[C@H]1CCc2ccc(Oc3ccc(Oc4ccccc4)c(C=O)c3)cc2C1 -US07189851B2,2,CCOC(=O)c1c(Cc2ccc(F)cc2F)nc2c(c1-c1ccc(C(=O)O)cc1)C(=O)N1CCC[C@@H]21.NN1CCc2ccccc21>>CCOC(=O)c1c(Cc2ccc(F)cc2F)nc2c(c1-c1ccc(C(=O)NN3CCc4ccccc43)cc1)C(=O)N1CCC[C@@H]21 -US05179112,7,COc1cc(C(=O)O)ccc1Cc1cn(C(C)=O)c2ccc([N+](=O)[O-])cc12>>COc1cc(C(=O)O)ccc1Cc1cn(C(C)=O)c2ccc(N)cc12 -US07307076B2,7,O=C(CCl)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12>>O=c1ccc2c(C(O)CCl)ccc(OCc3ccccc3)c2[nH]1 -US20130109718A1,1,CI.Cc1ccccc1[C@H](CC(=O)c1ccc(=O)[nH]c1)c1ccc(Br)cc1>>Cc1ccccc1[C@H](CC(=O)c1ccc(=O)n(C)c1)c1ccc(Br)cc1 -US20090264445A1,1,CCOC(=O)C=C(C)Cl.Oc1cccc(Br)c1>>CCOC(=O)/C=C(\C)Oc1cccc(Br)c1 -US20150141422A1,6,CCc1nc2cc(C(=O)OC)ccc2nc1-c1ccccc1>>CCc1nc2cc(C(=O)O)ccc2nc1-c1ccccc1 -US08093265B2,6,CC(=O)OC[C@@H](C)n1ccc2c(C(=O)NCc3ccc(C(F)(F)F)c(F)c3)c(C)ccc2c1=O>>Cc1ccc2c(=O)n([C@H](C)CO)ccc2c1C(=O)NCc1ccc(C(F)(F)F)c(F)c1 -US20100240638A1,1,C1COCCN1.CC(C)(C)OC(=O)N1Cc2ccc(Br)cc2C1>>CC(C)(C)OC(=O)N1Cc2ccc(N3CCOCC3)cc2C1 -US20020198197A1,9,COC(=O)c1coc(-c2cccc(C3=Nc4ccc(-n5cccc5)cc4NC(=O)C3)c2)n1.N>>NC(=O)c1coc(-c2cccc(C3=Nc4ccc(-n5cccc5)cc4NC(=O)C3)c2)n1 -US05348944,6,CCOC(=O)C(CCc1ccccc1)N[C@@H](C)C(=O)N1CC2CCCCC2[C@H]1C(=O)O>>C[C@H](NC(CCc1ccccc1)C(=O)O)C(=O)N1CC2CCCCC2[C@H]1C(=O)O -US07544690B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC[C@@H]1CC[C@@H](C(=O)O)CC1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)O)CC1 -US20100029657A1,3,CC1(C)OB(c2cccc(-c3nnco3)c2)OC1(C)C.CCOC(=O)N1C2CCC1CC(c1ccnc3c(I)c(-c4ccncc4)nn13)C2>>CCOC(=O)N1C2CCC1CC(c1ccnc3c(-c4cccc(-c5nnco5)c4)c(-c4ccncc4)nn13)C2 -US20040176422A1,1,CC1(C)COC(c2ccc(Cl)nc2)=N1.C[O-]>>COc1ccc(C2=NC(C)(C)CO2)cn1 -US20140107103A1,7,CNc1ccc(F)cc1[N+](=O)[O-]>>CNc1ccc(F)cc1N -US20110281859A1,9,Clc1nccc(N2CCC[C@@H]2COc2cccc3ccccc23)n1.NN>>NNc1nccc(N2CCC[C@@H]2COc2cccc3ccccc23)n1 -US20110275797A1,6,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(-n2cccn2)cc1O>>O=C(Nc1cc(-c2ccccc2)ccc1C(=O)O)c1ccc(-n2cccn2)cc1O -US20090062277A1,1,CC(C)(O)C1CCNCC1.COc1cc2nccc(-c3cnc(F)c(C)c3)c2cc1OC>>COc1cc2nccc(-c3cnc(N4CCC(C(C)(C)O)CC4)c(C)c3)c2cc1OC -US06599908B1,7,CCN(CC)CCOc1c(OC)cc([N+](=O)[O-])cc1OC>>CCN(CC)CCOc1c(OC)cc(N)cc1OC -US06974813B2,6,CCOC(=O)c1cnn(-c2ccccc2OC)c1C>>COc1ccccc1-n1ncc(C(=O)O)c1C -US20130324579A1,7,COc1cc(OC)nc(OCCn2cc([N+](=O)[O-])cn2)n1>>COc1cc(OC)nc(OCCn2cc(N)cn2)n1 -US20100239219A1,7,O=C(O)CCC(=O)c1cc2ccc3ccc4ccc5ccc6ccc1c1c6c5c4c3c21>>O=C(O)CCCc1cc2ccc3ccc4ccc5ccc6ccc1c1c6c5c4c3c21 -US20050107347A1,6,COC(=O)C(O)Cc1cc(Br)c(Oc2cc(/C=C/c3ccccc3)c(O)c(C(C)C)c2)c(Br)c1>>CC(C)c1cc(Oc2c(Br)cc(CC(O)C(=O)O)cc2Br)cc(/C=C/c2ccccc2)c1O -US06127541,1,C1COCCN1.N#Cc1ccccc1F>>N#Cc1ccccc1N1CCOCC1 -US07332498B2,2,CC(C)C(NC(=O)OCc1ccccc1)C(=O)Nc1ccncc1C(=O)O.NCc1ccccc1>>CC(C)C(NC(=O)OCc1ccccc1)C(=O)Nc1ccncc1C(=O)NCc1ccccc1 -US05449812,2,COC(=O)c1ccc(N(C)C(=O)OC)cc1S(=O)(=O)N=C=O.COc1cc(Cl)nc(N)n1>>COC(=O)c1ccc(N(C)C(=O)OC)cc1S(=O)(=O)NC(=O)Nc1nc(Cl)cc(OC)n1 -US03978009,7,C=C(C)C1CCC(C)=C1CC(C)C=O>>CC1=C(CC(C)C=O)C(C(C)C)CC1 -US07001895B2,2,CO.O=C(O)Cc1ccc(F)cc1>>COC(=O)Cc1ccc(F)cc1 -US05750704,1,Cc1ncc(CCl)s1.NCCCN>>Cc1ncc(CNCCCN)s1 -US20070197512A1,6,CCOC(=O)/C=C/C(=O)N1CC(C(C)C)Oc2cc(C)ccc21>>Cc1ccc2c(c1)OC(C(C)C)CN2C(=O)/C=C/C(=O)O -US20120270838A1,3,CC(C)(C)OC(=O)N1CCC2(CC1)N=C(c1cccc(Br)c1)NC2=O.Cc1noc(C)c1B(O)O>>Cc1noc(C)c1-c1cccc(C2=NC3(CCN(C(=O)OC(C)(C)C)CC3)C(=O)N2)c1 -US20040063691A1,3,CCCCC[Mg+].CCOC(=O)C(=O)Cl>>CCCCCC(=O)C(=O)OCC -US06670365B1,3,CSc1ccc(CC(=O)Cl)cc1.Fc1ccccc1>>CSc1ccc(CC(=O)c2ccc(F)cc2)cc1 -US07915411B2,1,Cc1ccccc1CBr.O=[N+]([O-])c1cc(O)ccc1Cl>>Cc1ccccc1COc1ccc(Cl)c([N+](=O)[O-])c1 -US08389507B2,6,CCN(C[C@H]1CCCN1C(=O)OC(C)(C)C)c1cccc(Oc2ccccc2)c1>>CCN(C[C@H]1CCCN1)c1cccc(Oc2ccccc2)c1 -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4cccc(Cl)c4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4cccc(Cl)c4)NC(=O)c4c[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US08536168B2,10,Cc1c(Cl)nnc(Cl)c1C.O=C1CCC(=O)N1Br>>Cc1c(Cl)nnc(Cl)c1CBr -US20120035370A1,1,C1COCCN1.CS(=O)(=O)c1cc([C@H](CC=O)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1>>CS(=O)(=O)c1cc([C@H](CCN2CCOCC2)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1 -US20060235021A1,3,CCCC[Sn](CCCC)(CCCC)c1ccncc1F.Fc1cnc(-c2cc(-c3cnnc(Cl)c3)ccc2F)c(F)c1>>Fc1cnc(-c2cc(-c3cnnc(-c4ccncc4F)c3)ccc2F)c(F)c1 -US06235731B1,8,CC(C)(C)OC(=O)N1CCC(O)C1>>CC(C)(C)OC(=O)N1CCC(=O)C1 -US20130172384A1,3,O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)n[nH]c2=O)C1.OB(O)c1ccc(Cl)cc1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(-c4ccc(Cl)cc4)cc3)n[nH]c2=O)C1 -US07741329B2,3,C[Sn](C)(C)C.Cc1nc(C(=O)N2CCC[C@H]2CNc2ncc(Br)cn2)c(-c2ccc(F)cc2)s1>>Cc1cnc(NC[C@@H]2CCCN2C(=O)c2nc(C)sc2-c2ccc(F)cc2)nc1 -US20080261941A1,6,C#CCCCOc1ccc(Oc2cccc(C=C3CCN(C(=O)OC(C)(C)C)CC3)c2)nc1>>C#CCCCOc1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1 -US05629406,1,CN(C(=O)CBr)c1ccc(OCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)C(=O)N2CCC[C@H]2C(=O)NC(C)(C)C)cc1.CNC>>CN(C)CC(=O)N(C)c1ccc(OCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)C(=O)N2CCC[C@H]2C(=O)NC(C)(C)C)cc1 -US08367824B2,7,COC(=O)c1cc(OC)c(OCCCCl)cc1[N+](=O)[O-]>>COC(=O)c1cc(OC)c(OCCCCl)cc1N -US07696210B2,1,CCN(CC)c1ccc(-c2nc3c(N4CCNCC4)cccc3[nH]2)cc1.CCn1cc(C=O)c(=O)[nH]c1=O>>CCN(CC)c1ccc(-c2nc3c(N4CCN(Cc5cn(CC)c(=O)[nH]c5=O)CC4)cccc3[nH]2)cc1 -US20120252801A1,2,CC(C)c1ccc(N)cc1.CCN1CC(C)(C)OC(=O)C1CC(=O)O>>CCN1CC(C)(C)OC(=O)C1CC(=O)Nc1ccc(C(C)C)cc1 -US08343967B2,1,C1CC2(CCN1)OCCO2.CCOC(=O)c1ccc(F)cc1>>CCOC(=O)c1ccc(N2CCC3(CC2)OCCO3)cc1 -US04191758,1,C=CCc1c(O)cc(Cc2cnc(N)nc2N)cc1OC.CO>>C=CCc1c(OC)cc(Cc2cnc(N)nc2N)cc1OC -US20090143383A1,1,CCCN(CCO)C(=O)OC(C)(C)C.Cc1nc(Cl)ccc1[N+](=O)[O-]>>CCCN(CCOc1ccc([N+](=O)[O-])c(C)n1)C(=O)OC(C)(C)C -US06710056B2,3,C=C(NC(C)=O)C(=O)OC.CC(C)(C)OC(=O)N[C@H](CCC(=O)OCc1ccccc1)COc1cc(C#N)ccc1I>>COC(=O)C(=Cc1ccc(C#N)cc1OC[C@@H](CCC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)NC(C)=O -US20080021012A1,9,NO.O=Cc1ccc(-c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)cn1>>O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C=NO)nc2)c(F)c1 -US04374140,9,COc1cnc(Cl)c(C(N)=O)c1>>COc1cnc(Cl)c(C#N)c1 -US04716161,1,COc1cc2c(cc1OC)S(=O)(=O)NC(=O)N2.COc1ccccc1N1CCN(CCCl)CC1>>COc1cc2c(cc1OC)S(=O)(=O)N(CCN1CCN(c3ccccc3OC)CC1)C(=O)N2 -US20050176775A1,7,CC(=O)OC(C)(C)C(=O)Nc1ccc(F)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1>>Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1cc(NC(=O)C(C)(C)O)ccc1F -US04528026,1,CCN.CSc1c(Cl)nc(Cl)nc1Cl>>CCNc1nc(Cl)c(SC)c(Cl)n1 -US07129257B1,7,C[C@@H](O)Cn1ncc2ccc(O)c([N+](=O)[O-])c21>>C[C@@H](O)Cn1ncc2ccc(O)c(N)c21 -US20150284375A1,6,C[C@H](NC(=O)OC(C)(C)C)c1ccc(CO)cc1>>C[C@H](N)c1ccc(CO)cc1 -US05691330,3,CC(=O)N1CCCc2ccsc2C1.O=C(Cl)CCl>>CC(=O)N1CCCc2cc(C(=O)CCl)sc2C1 -US20040063698A1,6,Cc1cc(COc2ccc(C(O)C(CN(Cc3ccccc3)C(=O)OC(C)(C)C)C(=O)NO)cc2)c2ccccc2n1>>Cc1cc(COc2ccc(C(O)C(CNCc3ccccc3)C(=O)NO)cc2)c2ccccc2n1 -US08859768B2,1,CC(=O)Nc1cc(-c2cc(-c3ncn(COCC[Si](C)(C)C)n3)c(Br)o2)c(C)cn1.CN(C)C1CCCNC1>>CC(=O)Nc1cc(-c2cc(-c3ncn(COCC[Si](C)(C)C)n3)c(N3CCCC(N(C)C)C3)o2)c(C)cn1 -US20050137202A1,4,C#Cc1ncccn1.CSc1cnc(NS(=O)(=O)c2ccccc2)c(I)c1>>CSc1cnc2c(c1)cc(-c1ncccn1)n2S(=O)(=O)c1ccccc1 -US20110098286A1,1,COc1cc2ncnc(Cl)c2cc1OC.c1ccc2c(C3CNCCN3)cccc2c1>>COc1cc2ncnc(N3CCNC(c4cccc5ccccc45)C3)c2cc1OC -US20150265617A1,3,F[C@@H]1CCN(CCn2nc(I)c3c(Cl)c(-c4ccccc4)nnc32)C1.OB(O)c1cccc(F)c1>>Fc1cccc(-c2nn(CCN3CC[C@@H](F)C3)c3nnc(-c4ccccc4)c(Cl)c23)c1 -US20090247567A1,1,Clc1ccncc1I.OCCc1ccsc1>>Ic1cnccc1OCCc1ccsc1 -US20060257987A1,1,CCc1ccc(OC)c(Br)c1.Oc1ccccc1>>CCc1ccc(OC)c(Oc2ccccc2)c1 -US20110136807A1,7,CCCOc1ccc([N+](=O)[O-])cc1C=O>>CCCOc1ccc([N+](=O)[O-])cc1CO -US20120214800A1,8,OC(c1cccnc1)c1nccnc1Cl>>O=C(c1cccnc1)c1nccnc1Cl -US20150266879A1,2,CCOC(=O)[C@@H]1Cc2cccnc2N1C(=O)[C@@H](N)C1CCOCC1.C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C>>CCOC(=O)[C@@H]1Cc2cccnc2N1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C1CCOCC1 -US20120022078A1,1,CN1CCNCC1.O=Cc1cc(Cl)ncc1F>>CN1CCN(Cc2cc(Cl)ncc2F)CC1 -US07994218B2,9,CC(C)(COS(=O)(=O)CCCCl)[C@@H](OCc1ccccc1)C(=O)OCCN1CCOCC1.[N-]=[N+]=[N-]>>CC(C)(COS(=O)(=O)CCCN=[N+]=[N-])[C@@H](OCc1ccccc1)C(=O)OCCN1CCOCC1 -US20110021448A1,1,O=C1c2ccccc2C(=O)N1[C@@H]1CC[C@@H](O)CC1.Oc1ccc(F)cc1>>O=C1c2ccccc2C(=O)N1[C@@H]1CC[C@H](Oc2ccc(F)cc2)CC1 -US20040067999A1,6,CCOC(=O)C1CCN(C(=O)Nc2ccc3c(c2C)c2ccccc2n3C(C)C)CC1>>Cc1c(NC(=O)N2CCC(C(=O)O)CC2)ccc2c1c1ccccc1n2C(C)C -US20130029991A1,2,CC(C)(C)OC(=O)N1CCC(CN)CC1.O=C(N[C@@H](CO)C(=O)O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC(CNC(=O)[C@H](CO)NC(=O)c2ccc(S(=O)(=O)Nc3ccccc3Oc3ccccc3)cc2)CC1 -US05153214,1,COC(=O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCOS(C)(=O)=O.c1c[nH]cn1>>COC(=O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCn1ccnc1 -US08202984B2,3,CC(=O)OC[C@H]1O[C@@H](c2ccc(C)c(Cc3ccc(Cl)s3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CN(C)c1cccc(B(O)O)c1>>CC(=O)OC[C@H]1O[C@@H](c2ccc(C)c(Cc3ccc(-c4cccc(N(C)C)c4)s3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O -US20120214784A1,7,CCOC(=O)c1nn(-c2ccccc2F)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12>>OCc1nn(-c2ccccc2F)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12 -US20100144694A1,1,CC1(C)NN(C2CCCCC2)C1=O.Cc1ccc(C(=O)Cl)c(C)c1>>Cc1ccc(C(=O)N2N(C3CCCCC3)C(=O)C2(C)C)c(C)c1 -US20060194969A1,6,CCOC(=O)c1cc(NCc2c(C)cccc2C)c2nc(C)n(C)c2c1>>Cc1cccc(C)c1CNc1cc(C(=O)O)cc2c1nc(C)n2C -US20100216746A1,6,COc1ccc2c(c1)c1c(n2C(=O)OC(C)(C)C)C(=O)N(Cc2ccc(Cl)c(Oc3cc(Cl)cc(C#N)c3)c2F)CC1>>COc1ccc2[nH]c3c(c2c1)CCN(Cc1ccc(Cl)c(Oc2cc(Cl)cc(C#N)c2)c1F)C3=O -US20110112103A1,3,CC(C)(C)c1ccc(B(O)O)cc1.Cc1cnc(Cl)nc1>>Cc1cnc(-c2ccc(C(C)(C)C)cc2)nc1 -US05026856,1,Fc1ccc2c(c1)CNC2.O=C(O)c1cn(-c2ccc(F)cc2)c2c(F)c(F)c(F)cc2c1=O>>O=C(O)c1cn(-c2ccc(F)cc2)c2c(F)c(N3Cc4ccc(F)cc4C3)c(F)cc2c1=O -US20100029722A1,4,C#Cc1ccccc1.Cc1nc(N=[N+]=[N-])sc1C(=O)NCc1ccccc1>>Cc1nc(-n2cc(-c3ccccc3)nn2)sc1C(=O)NCc1ccccc1 -US20080161295A1,1,CN.Cc1ccc(N2c3ccccc3CN(CCCCl)S2(=O)=O)cc1>>CNCCCN1Cc2ccccc2N(c2ccc(C)cc2)S1(=O)=O -US04569801,2,CCCCCCCNCC.O=C(O)CCCc1ccc([N+](=O)[O-])cc1>>CCCCCCCN(CC)C(=O)CCCc1ccc([N+](=O)[O-])cc1 -US20110319619A1,1,Cc1ccc(N)cc1.N#CCCCBr>>Cc1ccc(NCCCC#N)cc1 -US06291481B1,7,N#CCN1CCC(COC(=O)c2cc(Cl)c(N)c3c2OCCO3)CC1>>NCCN1CCC(COC(=O)c2cc(Cl)c(N)c3c2OCCO3)CC1 -US08080570B2,7,CC(C)(C)OC(=O)NC(CC(=O)O)c1ccccc1>>CC(C)(C)OC(=O)NC(CCO)c1ccccc1 -US20110183972A1,1,C1COCCN1.COc1cc(C#N)c(N)cc1OCCCCl>>COc1cc(C#N)c(N)cc1OCCCN1CCOCC1 -US04871537,7,CCCC(C)=CCCBr>>CCCC(C)CCCBr -US20140357858A1,6,COc1ccccc1CC(=O)Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1>>O=C(Cc1ccccc1O)Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1 -US20150056141A1,3,CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(Br)ccc12.Cc1cccc(B(O)O)c1>>CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(-c3cccc(C)c3)ccc12 -US08138172B2,1,CCCCOc1nc(N)c2[nH]c(=O)n(CCCN)c2n1.COC(=O)Cc1cccc(C=O)c1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCNCc3cccc(CC(=O)OC)c3)c2n1 -US20090221653A1,2,CCOC(=O)COCCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)COCCCOS(=O)(=O)c1ccc(C)cc1 -US07829584B2,1,CCOC(=O)Cc1nc(Cl)ccc1Cl.NCC(F)(F)c1ccccc1>>CCOC(=O)Cc1nc(NCC(F)(F)c2ccccc2)ccc1Cl -US07560558B2,1,CC(C)COC(=O)c1ccccc1O.COc1cc2nccc(Cl)c2cc1OC>>COc1cc2nccc(Oc3ccccc3C(=O)OCC(C)C)c2cc1OC -US09056859B2,6,CCc1c(CCN2CCN(C(=O)OC(C)(C)C)CC2)ccc2c1COC2=O>>CCc1c(CCN2CCNCC2)ccc2c1COC2=O -US20030027795A1,1,COc1ccc(NS(=O)(=O)c2ccc(N3CCC(=O)CC3)cc2)cc1OC.NCC(O)COc1ccc(OCc2ccccc2)cc1>>COc1ccc(NS(=O)(=O)c2ccc(N3CCC(NC[C@H](O)COc4ccc(OCc5ccccc5)cc4)CC3)cc2)cc1OC -US20100069347A1,3,C#C[Si](C)(C)C.CC(=O)OCC(O)(C#Cc1ccc([C@@H]2[C@@H](CC[C@H](OC(C)=O)c3ccc(F)cc3)C(=O)N2c2ccc(OS(=O)(=O)C(F)(F)F)cc2)cc1)COC(C)=O>>CC(=O)OCC(O)(C#Cc1ccc([C@@H]2[C@@H](CC[C@H](OC(C)=O)c3ccc(F)cc3)C(=O)N2c2ccc(C#C[Si](C)(C)C)cc2)cc1)COC(C)=O -US04742057,6,COc1ccc2[nH]cc(C3CCN(C(C)=O)CC3)c2c1>>COc1ccc2[nH]cc(C3CCNCC3)c2c1 -US20100331298A1,1,O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1(CC2CC2)CCN(Cc2ccc3cc[nH]c(=O)c3c2)CC1.OB(O)C1CC1>>O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1(CC2CC2)CCN(Cc2ccc3ccn(C4CC4)c(=O)c3c2)CC1 -US20110098311A1,7,COc1cc([N+](=O)[O-])ccc1C(C)(C)C>>COc1cc(N)ccc1C(C)(C)C -US09073947B2,2,Nc1cccc(Oc2ncnc(N)c2-c2ccc(Oc3ccccc3)cc2)c1.O=C(O)/C=C/CN1CCOCC1>>Nc1ncnc(Oc2cccc(NC(=O)/C=C/CN3CCOCC3)c2)c1-c1ccc(Oc2ccccc2)cc1 -US07772183B2,2,CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(O)CN2C1=O.O=C(Cl)c1ccc2c(c1)OCCO2>>CC(C)(C)OC(=O)NC1CCCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(OC(=O)c3ccc4c(c3)OCCO4)CN2C1=O -US06313132B1,3,C=CC#N.CC(C)N(CC[C@H](c1ccccc1)c1cc(Br)ccc1OCc1ccccc1)C(C)C>>CC(C)N(CC[C@H](c1ccccc1)c1cc(C=CC#N)ccc1OCc1ccccc1)C(C)C -US20120245148A1,1,Brc1ccc(N2CCC3(CC2)OCCO3)cc1.CC(C)(C)OC(=O)N1CCNc2ccccc21>>CC(C)(C)OC(=O)N1CCN(c2ccc(N3CCC4(CC3)OCCO4)cc2)c2ccccc21 -US20090181942A1,7,COC(=O)CC[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(C=O)ccc21>>COC(=O)CC[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(CO)ccc21 -US05387714,2,CN.Cc1ccccc1C(=O)C(=O)Cl>>CNC(=O)C(=O)c1ccccc1C -US07786109B2,1,CC(C)N1CCC(Oc2ccc3c(c2)cc2n3[C@H](C)CNC2=O)CC1.Cc1onc(-c2ccccc2)c1CBr>>Cc1onc(-c2ccccc2)c1CN1C[C@@H](C)n2c(cc3cc(OC4CCN(C(C)C)CC4)ccc32)C1=O -US20080262050A1,6,COc1cc2cc(N3CC(=O)NS3(=O)=O)c(OCc3ccccc3)cc2oc1=O>>COc1cc2cc(N3CC(=O)NS3(=O)=O)c(O)cc2oc1=O -US06465478B1,3,O=C1CCCCCC1.O=C1NCN(c2ccccc2)C12CCNCC2.[C-]#N>>N#CC1(N2CCC3(CC2)C(=O)NCN3c2ccccc2)CCCCCC1 -US20060229312A1,1,CC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1.CI>>CC(=O)N(C)c1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 -US20110065702A1,3,O=C1Cc2ccccc2N1.O=Cc1ccc2[nH]nnc2c1>>O=C1Nc2ccccc2/C1=C\c1ccc2[nH]nnc2c1 -US05073564,3,C(#Cc1cc2ccccc2s1)c1cccs1.CN(C)C=O>>O=Cc1ccc(C#Cc2cc3ccccc3s2)s1 -US05552550,9,COc1cc(CBr)cc2c(Br)ccc(OC(C)C)c12>>COc1cc(C)cc2c(Br)ccc(OC(C)C)c12 -US20060014790A1,9,[N-]=[N+]=NC1(c2cc(Br)cs2)CCCCC1>>NC1(c2cc(Br)cs2)CCCCC1 -US20020072608A1,1,CC(C)(C)OC(=O)N[C@@H]1CNC[C@@H]1CF.COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>COc1c(N2C[C@@H](NC(=O)OC(C)(C)C)[C@@H](CF)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 -US06395738B1,2,CN1CCNCC1.COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)c2cc(C(=O)O)oc12>>COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)c2cc(C(=O)N3CCN(C)CC3)oc12 -US07652004B2,2,C1COCCN1.COc1ccc2c(c1)C=C(c1ocnc1C(=O)O)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)OC(C)(C)C)cc21>>COc1ccc2c(c1)C=C(c1ocnc1C(=O)N1CCOCC1)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)OC(C)(C)C)cc21 -US04120691,2,Cc1nnc(N)nc1C.O=C=NS(=O)(=O)c1ccccc1Cl>>Cc1nnc(NC(=O)NS(=O)(=O)c2ccccc2Cl)nc1C -US20060205952A1,9,COC(=O)c1ccc2cc(OC)c(C(N)=O)cc2c1>>COC(=O)c1ccc2cc(OC)c(C#N)cc2c1 -US08329823B2,7,O=C(O)Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>O=[N+]([O-])c1ccc(CCO)c([N+](=O)[O-])c1 -US20120283216A1,1,CCC(Br)C(=O)OC.O=S(=O)(Oc1ccc2ccc(O)cc2c1)C(F)(F)F>>CCC(Oc1ccc2ccc(OS(=O)(=O)C(F)(F)F)cc2c1)C(=O)OC -US09139576B2,2,CS(=O)(=O)Cl.OCc1ccc(-c2ccc3c(nnn3CC3CC3)c2Cl)cc1>>CS(=O)(=O)OCc1ccc(-c2ccc3c(nnn3CC3CC3)c2Cl)cc1 -US20140275199A1,6,COC1(C(F)(F)F)CCC2(CC1)OCCO2>>COC1(C(F)(F)F)CCC(=O)CC1 -US08404859B2,6,COC(=O)[C@H](CNC(=O)OC(C)(C)C)NC(=O)c1sc(C(=O)NCc2ccc(F)c(O)c2)cc1C>>COC(=O)[C@H](CN)NC(=O)c1sc(C(=O)NCc2ccc(F)c(O)c2)cc1C -US20090192336A1,1,OCCCBr.Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>OCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl -US07888362B2,1,CN1CCc2ccc(O)cc2C1=O.ClCCCCBr>>CN1CCc2ccc(OCCCCCl)cc2C1=O -US20110257151A1,2,CC1(C)Cc2cc(Cl)cc(C(=O)O)c2NC1c1cccc(N2CCOCC2)c1.CS(N)(=O)=O>>CC1(C)Cc2cc(Cl)cc(C(=O)NS(C)(=O)=O)c2NC1c1cccc(N2CCOCC2)c1 -US20080045526A1,3,O=C(O)c1ccc2c(n1)COC2=O.O=C1Cc2cc(F)ccc2N1>>O=C1Nc2ccc(F)cc2C1=C1OCc2nc(C(=O)O)ccc21 -US04754050,1,Fc1ccc(CBr)cc1.Nc1c2c(nc3ccccc13)CCCC2=O>>O=C1CCCc2nc3ccccc3c(NCc3ccc(F)cc3)c21 -US04150153,2,O=C(Cl)c1ccccc1.OC(Cn1ccnc1)c1ccc2ccccc2c1>>O=C(OC(Cn1ccnc1)c1ccc2ccccc2c1)c1ccccc1 -US20140309220A1,6,CCOC(=O)c1ccc(S(=O)C(C)C)cc1>>CC(C)S(=O)c1ccc(C(=O)O)cc1 -US05095014,2,CN.O=C(Cl)N1CC(Oc2ccccc2Cl)C1>>CNC(=O)N1CC(Oc2ccccc2Cl)C1 -US20060241172A1,3,COc1cccc(F)c1B(O)O.Clc1ccccc1Br>>COc1cccc(F)c1-c1ccccc1Cl -US20150210655A1,1,CI.O=c1ccc2ccc(Br)cc2[nH]1>>Cn1c(=O)ccc2ccc(Br)cc21 -US07829584B2,9,[N-]=[N+]=NCC(F)(F)c1ncccn1>>NCC(F)(F)c1ncccn1 -US20030125317A1,6,CC(C)(C)OC(=O)N(CCCOc1ccc2c(c1)CN(Cc1ccc(N)cc1)C(=O)C(CC(=O)O)C2)c1ccccn1>>Nc1ccc(CN2Cc3cc(OCCCNc4ccccn4)ccc3CC(CC(=O)O)C2=O)cc1 -US20090209522A1,1,CC(C)(C)c1ccc(Br)c(O)c1.COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Br)n1>>COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Oc2cc(C(C)(C)C)ccc2Br)n1 -US20060217418A1,2,Cc1ccc(C(O)(C(=O)O)c2ccc(C)cc2)cc1.Cc1ccc(NC(=O)C(C)C)cc1C1CCN(CCCN)CC1>>Cc1ccc(C(O)(C(=O)NCCCN2CCC(c3cc(NC(=O)C(C)C)ccc3C)CC2)c2ccc(C)cc2)cc1 -US20080004309A1,2,CCOC(=O)c1ncc2nc(-c3ccc(Oc4ccccc4)cc3)sc2c1O.NCC(=O)O>>O=C(O)CNC(=O)c1ncc2nc(-c3ccc(Oc4ccccc4)cc3)sc2c1O -US20040225111A1,1,CC(C)(C)OC(=O)[C@H](Cc1ccc(O)cc1)Nc1nc2ccccc2s1.CCOC(=O)CCCBr>>CCOC(=O)CCCOc1ccc(C[C@H](Nc2nc3ccccc3s2)C(=O)OC(C)(C)C)cc1 -US03994940,1,CN(C)CCc1nnc(CO)n1-c1ccccc1C(=O)c1ccccc1Cl.O=C1NC(=O)c2ccccc21>>CN(C)CCc1nnc(CN2C(=O)c3ccccc3C2=O)n1-c1ccccc1C(=O)c1ccccc1Cl -US20120184561A1,2,CN(C)CCCN(C)c1ccc(N)cc1C(F)(F)F.O=C(O)Cc1ccc(-n2cnc3cccnc32)cc1Cl>>CN(C)CCCN(C)c1ccc(NC(=O)Cc2ccc(-n3cnc4cccnc43)cc2Cl)cc1C(F)(F)F -US05606095,10,COC(=O)Cc1ccccc1C.O=C1CCC(=O)N1Br>>COC(=O)Cc1ccccc1CBr -US07176199B2,1,CCOC(=O)C1CCNCC1.COc1ccccc1B(O)O>>CCOC(=O)C1CCN(c2ccccc2OC)CC1 -US04309443,1,COC(=O)/C=C/c1ccc(CC(C)=O)cc1.NCC(O)c1ccccc1>>COC(=O)/C=C/c1ccc(CC(C)NCC(O)c2ccccc2)cc1 -US20130172317A1,1,CCSc1nc(=O)n(C(C)(C)C)c(=O)[nH]1.Clc1ccc(CBr)cc1>>CCSc1nc(=O)n(C(C)(C)C)c(=O)n1Cc1ccc(Cl)cc1 -US20150158863A1,7,COc1cnc([N+](=O)[O-])c(NC(=O)CCl)c1>>COc1cnc(N)c(NC(=O)CCl)c1 -US09067937B2,1,CN(C)[C@@H]1CC[C@@H](N)CC1.CS(=O)(=O)c1cnc2ccc(Cl)nc2c1Cl>>CN(C)[C@@H]1CC[C@@H](Nc2c(S(C)(=O)=O)cnc3ccc(Cl)nc23)CC1 -US04024255,2,Nc1nnn[nH]1.O=C(O)c1c[nH]c2nc(Cl)ccc2c1=O>>O=C(Nc1nnn[nH]1)c1c[nH]c2nc(Cl)ccc2c1=O -US20100273833A1,6,CC(=O)Nc1cc(-c2c(-c3ccc(F)cc3)nc3n2CCS3)ccn1>>Nc1cc(-c2c(-c3ccc(F)cc3)nc3n2CCS3)ccn1 -US06949542B2,2,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2cccnc2C2CC2)c1.CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1N>>CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cccnc2C2CC2)c1 -US08222256B2,1,CC(C)c1cc(Nc2cc(Cl)nc(Cl)n2)n[nH]1.NCc1cc(-c2ccccc2)no1>>CC(C)c1cc(Nc2cc(Cl)nc(NCc3cc(-c4ccccc4)no3)n2)n[nH]1 -US20080227941A1,1,C=CCC(CC=C)CO[SiH2]c1ccc(I)cc1.C[Sn](C)(C)Cl>>C=CCC(CC=C)CO[SiH2]c1ccc([Sn](C)(C)C)cc1 -US07803822B2,1,CC(Br)c1ccccc1.CCNC(=O)c1ccc(-n2cc(C(=O)NC3CC3)nn2)c(O)c1>>CCNC(=O)c1ccc(-n2cc(C(=O)NC3CC3)nn2)c(OC(C)c2ccccc2)c1 -US04927919,7,O=C(O)C=Cc1ccc2c(c1)OCO2>>O=C(O)CCc1ccc2c(c1)OCO2 -US20110136801A1,1,CCNCC.COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC2(C(=O)OC)CC2)c1)C(=O)CCl>>CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OC2(C(=O)OC)CC2)c1 -US20130203749A1,7,COc1ccc(C(C)(C)C#N)cc1>>COc1ccc(C(C)(C)CN)cc1 -US06794397B2,2,CCOc1ccc(N)c([N+](=O)[O-])c1.O=C(O)c1cncc(Br)c1>>CCOc1ccc(NC(=O)c2cncc(Br)c2)c([N+](=O)[O-])c1 -US08853196B2,6,CCOC(=O)NC1COc2ccc(OC)cc2C1Cc1ccccc1>>CCOC(=O)NC1COc2ccc(O)cc2C1Cc1ccccc1 -US20080076774A1,6,Cc1c(NCCN2CCCC2)cc(-c2nc(-c3ccccc3)no2)cc1N1CCN(C(=O)OC(C)(C)C)CC1>>Cc1c(NCCN2CCCC2)cc(-c2nc(-c3ccccc3)no2)cc1N1CCNCC1 -US20090281135A1,6,CCOC(=O)C1=C(c2ccc(Cl)c(Cl)c2)CN(Cc2ccccc2)CC1>>CCOC(=O)C1=C(c2ccc(Cl)c(Cl)c2)CNCC1 -US20040220191A1,1,C1CCNCC1.CN(C(=O)c1ccc(C2CCCCC2)cc1)c1ccc(N2CCC(Br)C2=O)cc1>>CN(C(=O)c1ccc(C2CCCCC2)cc1)c1ccc(N2CCC(N3CCCCC3)C2=O)cc1 -US20100216762A1,6,O=C(Cc1cccc(C(F)(F)F)c1)c1ccc(C2OCCO2)cc1>>O=Cc1ccc(C(=O)Cc2cccc(C(F)(F)F)c2)cc1 -US20040002526A1,3,CCCC[Sn](CCCC)(CCCC)c1ccc(S(N)=O)cc1.O=Cc1ccc(Br)o1>>NS(=O)c1ccc(-c2ccc(C=O)o2)cc1 -US20060083947A1,3,O=C1c2ccccc2C(=O)c2cc(Cl)ccc21.OB(O)c1ccccc1>>O=C1c2ccccc2C(=O)c2cc(-c3ccccc3)ccc21 -US20150119404A1,7,CCOc1ccc(F)c(-c2cc(C)nc(C3=N[C@]4(CC3)CCN(C)C4=O)n2)c1>>CCOc1ccc(F)c(-c2cc(C)nc([C@@H]3CC[C@]4(CCN(C)C4=O)N3)n2)c1 -US06951879B2,1,CCNCC.FC(F)(F)c1ccc(-c2nsc3cc(OCCCCBr)ccc23)cc1>>CCN(CC)CCCCOc1ccc2c(-c3ccc(C(F)(F)F)cc3)nsc2c1 -US05627173,1,COc1cc(C=C(C(=O)OC(C)C)P(=O)(OC)OC)cc(OC)c1O.COc1ccc(CCl)cc1>>COc1ccc(COc2c(OC)cc(C=C(C(=O)OC(C)C)P(=O)(OC)OC)cc2OC)cc1 -US20140179672A1,3,O=Cc1c(F)ccc(Br)c1F.OB(O)C1CC1>>O=Cc1c(F)ccc(C2CC2)c1F -US20120135964A1,6,CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CNC(=O)OCc1ccccc1)COC(=O)Nc1cc2ccccc2cn1>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CN)COC(=O)Nc1cc2ccccc2cn1 -US20060041144A1,2,COc1ccc(-c2ncccc2N)cc1OC.O=C(O)C(=C(Cl)Cl)c1ccccc1Cl>>COc1ccc(-c2ncccc2NC(=O)C(=C(Cl)Cl)c2ccccc2Cl)cc1OC -US20140135320A1,6,COc1ccc(C(C)(C)C)cc1-c1ccc(C)cn1>>Cc1ccc(-c2cc(C(C)(C)C)ccc2O)nc1 -US05362879,6,CCOC(=O)N(Cc1nc(-c2ccccc2)c(-c2ccccc2)o1)c1cccc(OCC(=O)OC)c1>>CCOC(=O)N(Cc1nc(-c2ccccc2)c(-c2ccccc2)o1)c1cccc(OCC(=O)O)c1 -US20050003303A1,2,C=C(C)C(=O)Cl.CS(=O)(=O)NC1CCCCC1O>>C=C(C)C(=O)OC1CCCCC1NS(C)(=O)=O -US20090074738A1,1,BrCc1ccccc1.OCCc1ccc(Br)cc1>>Brc1ccc(CCOCc2ccccc2)cc1 -US07019034B2,3,CCOC(=O)C=C(C)CP(=O)(OCC)OCC.CCOc1cc2c(cc1/C(CC)=C(/F)C=O)C(C)(C)CCC2(C)C>>CCOC(=O)/C=C(C)/C=C/C(F)=C(/CC)c1cc2c(cc1OCC)C(C)(C)CCC2(C)C -US20090069340A1,1,Cn1c(CBr)c(Br)c(=O)n1-c1ccccc1.Fc1cccc(CCCC2CCNCC2)c1>>Cn1c(CN2CCC(CCCc3cccc(F)c3)CC2)c(Br)c(=O)n1-c1ccccc1 -US07034152B2,7,COC(=O)C1=CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1COCc1ccccc1>>CC(C)(C)[Si](C)(C)O[C@H]1CC=C(CO)[C@@H]1COCc1ccccc1 -US20030229089A1,2,COc1ccc(CNc2nc(SC)nc(OC)c2C(=O)O)cc1Cl.NCc1ncccn1>>COc1ccc(CNc2nc(SC)nc(OC)c2C(=O)NCc2ncccn2)cc1Cl -US05834401,2,COC(=O)C(C)(C)NCC(C)=O.O=C(O)Cc1ccsc1>>COC(=O)C(C)(C)N(CC(C)=O)C(=O)Cc1ccsc1 -US20100048582A1,2,CN1CCN(c2cc(N)ccn2)CC1.O=S(=O)(Cl)c1cccc(OC(F)F)c1>>CN1CCN(c2cc(NS(=O)(=O)c3cccc(OC(F)F)c3)ccn2)CC1 -US20150266881A1,1,N[C@@H]1C[C@H]1c1cccc(C(=O)NC2CCC(F)(F)CC2)c1.O=CC1CC1>>O=C(NC1CCC(F)(F)CC1)c1cccc([C@@H]2C[C@H]2NCC2CC2)c1 -US06350749B1,1,Cc1ccnc2c1C(=O)CC(c1ccco1)C2.N=C(NN)NO>>Cc1ccnc2c1C(=NNC(=N)NO)CC(c1ccco1)C2 -US05610144,6,COC(=O)Cc1cccc(NC(=O)NCC(=O)N2[C@H](c3ccccc3)CC[C@@H]2c2ccccc2)c1>>O=C(O)Cc1cccc(NC(=O)NCC(=O)N2[C@H](c3ccccc3)CC[C@@H]2c2ccccc2)c1 -US06562830B1,3,C=CC(=O)N1CCN(C)CC1.CCCOc1ccc(Br)cc1-c1nc2c(C)cccc2c(=O)[nH]1>>CCCOc1ccc(C=CC(=O)N2CCN(C)CC2)cc1-c1nc2c(C)cccc2c(=O)[nH]1 -US20120329818A1,1,CC1(C(=O)Nc2cccc(Oc3ccc(F)cc3)c2)CCNCC1.Clc1c[nH]c2ncnc(Cl)c12>>CC1(C(=O)Nc2cccc(Oc3ccc(F)cc3)c2)CCN(c2ncnc3[nH]cc(Cl)c23)CC1 -US20070042996A1,6,COc1ccc2ncsc2c1>>Oc1ccc2ncsc2c1 -US20110269738A1,1,CCc1c(C=O)cccc1-c1cnc(-c2ccc(OC(C)C)c(Cl)c2)s1.COC(=O)C1CNC1>>CCc1c(CN2CC(C(=O)OC)C2)cccc1-c1cnc(-c2ccc(OC(C)C)c(Cl)c2)s1 -US20100130743A1,3,Cc1cc(Cn2cc(I)c(C(F)(F)F)n2)ccc1[N+](=O)[O-].FC(F)(F)C(F)(F)I>>Cc1cc(Cn2cc(C(F)(F)C(F)(F)F)c(C(F)(F)F)n2)ccc1[N+](=O)[O-] -US09133171B2,3,Fc1cnc(Cl)nc1Cl.OB(O)c1cccc2c1OCCC2>>Fc1cnc(Cl)nc1-c1cccc2c1OCCC2 -US06822100B2,1,CCOC(=O)C1CC1C(=O)Cl.Cc1ccc(S)cc1>>CCOC(=O)C1CC1C(=O)Sc1ccc(C)cc1 -US08796455B2,9,CC1(O)CC(c2nc(Br)c3c(Cl)nccn23)C1.N>>CC1(O)CC(c2nc(Br)c3c(N)nccn23)C1 -US06107297,1,Clc1ccnc(Cl)n1.O=c1[nH]cc(C2c3ccccc3C=Cc3ccccc32)c(=O)[nH]1>>O=c1[nH]c(=O)n(-c2ccnc(Cl)n2)cc1C1c2ccccc2C=Cc2ccccc21 -US08563584B2,1,FC(F)CNCc1ccc(Cl)nc1.OC1=CC(=S)OC1>>FC(F)CN(Cc1ccc(Cl)nc1)C1=CC(=S)OC1 -US04160836,1,ClCCCCn1cnc2ccccc21.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=c1[nH]c2ccccc2n1C1CCN(CCCCn2cnc3ccccc32)CC1 -US20100087446A1,7,CCOC(=O)C(C)(C)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)C(C)(C)c1ccc(N)cc1 -US20080021217A1,8,O=C(OO)c1cccc(Cl)c1.c1cnc2[nH]ccc2c1>>[O-][n+]1cccc2cc[nH]c21 -US07462639B2,2,CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4N)nc3cc21.O=C(O)c1ccncc1>>CCN1C(=O)C(C)(C)c2cc3[nH]c(-c4n[nH]cc4NC(=O)c4ccncc4)nc3cc21 -US05310740,6,COC(=O)C(Cc1ccccc1)CS(=O)(=O)N1CCN(Cc2ccccc2)CC1>>COC(=O)C(Cc1ccccc1)CS(=O)(=O)N1CCNCC1 -US08119676B2,6,CC(C)(C)OC(=O)N1CCC(N2CCN(C(=O)OCc3ccccc3)CC2)CC1>>CC(C)(C)OC(=O)N1CCC(N2CCNCC2)CC1 -US20140171430A1,1,Cc1cc(Cl)nc2ccccc12.O=C(c1ccccc1-c1ccccc1)N1CC2CNCC2C1>>Cc1cc(N2CC3CN(C(=O)c4ccccc4-c4ccccc4)CC3C2)nc2ccccc12 -US04013692,2,CCO.O=C(O)Cc1oc2cccc-2cc1-c1ccccc1>>CCOC(=O)Cc1oc2cccc-2cc1-c1ccccc1 -US20150087823A1,1,CCCCCCC/C=C/C(=O)N1CCC(O)CC1.CI>>CCCCCCC/C=C/C(=O)N1CCC(OC)CC1 -US05348961,1,CCOC(=O)C(=CNC1CC1)C(=O)c1c(N)c(F)c(F)c(OC(F)F)c1F>>CCOC(=O)c1cn(C2CC2)c2c(OC(F)F)c(F)c(F)c(N)c2c1=O -US07812166B2,2,Cn1nc(N)c2c(-c3ccc(N)cc3)cncc21.O=C=Nc1ccc(F)c(Cl)c1>>Cn1nc(N)c2c(-c3ccc(NC(=O)Nc4ccc(F)c(Cl)c4)cc3)cncc21 -US20080280855A1,1,C[Si](C)(C)CCOCCl.Cc1nc2c(OCc3ccccc3)cc(Br)cc2[nH]1>>Cc1nc2c(OCc3ccccc3)cc(Br)cc2n1COCC[Si](C)(C)C -US08093239B2,1,C1CNCCN1.CCOc1cc(F)ccc1[N+](=O)[O-]>>CCOc1cc(N2CCNCC2)ccc1[N+](=O)[O-] -US08318949B2,2,Cc1nc(N2CCN(CC3CC3)C2=O)sc1C(=O)O.NCc1ccncn1>>Cc1nc(N2CCN(CC3CC3)C2=O)sc1C(=O)NCc1ccncn1 -US20150065482A1,1,N#Cc1ccc(F)cc1Br.O=C(O)c1n[nH]c2c1CCCC2>>N#Cc1ccc(-n2nc(C(=O)O)c3c2CCCC3)cc1Br -US07807674B2,1,CC(C)c1cc(Cl)nnc1Cl.OCCc1cc(Cl)c(O)c(Cl)c1>>CC(C)c1cc(Oc2c(Cl)cc(CCO)cc2Cl)nnc1Cl -US20120220609A1,6,Cc1nc(CC2CCN(c3ccc(-c4ccc(CO[Si](C)(C)C(C)(C)C)cc4)cc3)CC2)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1>>Cc1nc(CC2CCN(c3ccc(-c4ccc(CO)cc4)cc3)CC2)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1 -US04659708,1,COc1cc(NCCCCCCN2CCNCC2)c2nccc(C)c2c1.OCC(O)CCl>>COc1cc(NCCCCCCN2CCN(CC(O)CO)CC2)c2nccc(C)c2c1 -US20070191447A1,6,CCOC(=O)C(C)n1c(=O)n2c3c(cc(Br)cc31)CCC2>>CC(C(=O)O)n1c(=O)n2c3c(cc(Br)cc31)CCC2 -US07902367B2,6,C[SiH](C)OC(C1CCCN(C(=O)OCc2ccccc2)C1)C(C)(C)C>>C[SiH](C)OC(C1CCCNC1)C(C)(C)C -US07544704B2,3,C#Cc1c(-c2ccccc2)noc1C.Cc1cccnc1Br>>Cc1cccnc1C#Cc1c(-c2ccccc2)noc1C -US20050171164A1,1,CC(O)CN.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(Br)c1S(=O)(=O)C(F)(F)F>>CC(O)CNc1c(S(=O)(=O)C(F)(F)F)c(C#N)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl -US20060040949A1,8,COc1ccc2ncnc(OCC3CCC(O)CC3)c2c1>>COc1ccc2ncnc(OCC3CCC(=O)CC3)c2c1 -US20060069128A1,7,COC(=O)c1cc(-c2nnnn2C)cc([N+](=O)[O-])c1>>COC(=O)c1cc(N)cc(-c2nnnn2C)c1 -US20140051679A1,2,Cc1ccccc1C(N)C1CC1.O=C(O)c1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1>>Cc1ccccc1C(NC(=O)c1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1)C1CC1 -US20110112120A9,1,CC1(C)Cc2cc(B(O)O)ccc2O1.CCCc1nc(CC)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(CC)n(-c2ccc3c(c2)CC(C)(C)O3)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20080255105A1,6,CCOC(=O)c1ccc(-c2cc(NC(=O)C3CCCCC3)ccc2Cl)cc1>>O=C(O)c1ccc(-c2cc(NC(=O)C3CCCCC3)ccc2Cl)cc1 -US20020173654A1,2,CCCCc1nc2c(N)nc3cccnc3c2n1CCCCN.Cc1cn(CC(=O)O)c(=O)nc1O>>CCCCc1nc2c(N)nc3cccnc3c2n1CCCCNC(=O)Cn1cc(C)c(O)nc1=O -US07919509B2,1,CC1(c2ccc3c(c2)OCCO3)NC(=O)NC1=O.CCCc1c(OCCCCBr)ccc2c(C(F)(F)F)cc(=O)oc12>>CCCc1c(OCCCCN2C(=O)NC(C)(c3ccc4c(c3)OCCO4)C2=O)ccc2c(C(F)(F)F)cc(=O)oc12 -US20040122244A1,1,COc1c(C)c(Cc2ccc(O)c(C(=O)N3CCCCC3)c2)c(OC)c(OC)c1OC.OB(O)c1ccncc1>>COc1c(C)c(Cc2ccc(Oc3ccncc3)c(C(=O)N3CCCCC3)c2)c(OC)c(OC)c1OC -US06265434B1,6,COC(=O)c1ccc(CCCC2CCN(C[C@H]3CN([C@@H](C(=O)O)C4CCCCC4)C[C@@H]3c3ccccc3)CC2)cc1>>O=C(O)c1ccc(CCCC2CCN(C[C@H]3CN([C@@H](C(=O)O)C4CCCCC4)C[C@@H]3c3ccccc3)CC2)cc1 -US20100016586A1,1,Clc1ccc(C2(CBr)CC2)cc1.Nc1ncnc2[nH]c(Sc3cc4c(cc3Br)OCO4)nc12>>Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CC1(c2ccc(Cl)cc2)CC1 -US20110053897A1,9,CC(C)(C)Nc1nc(Cl)cc2ncn(CCO)c(=O)c12.[NH4+]>>CC(C)(C)Nc1nc(N)cc2ncn(CCO)c(=O)c12 -US20120065195A1,3,CC1(C)CC(=O)c2cc(Br)ccc2C1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1CC(C)(C)Cc2ccc(Br)cc21 -US20050107410A1,1,Cc1ccc2c(OCCBr)cccc2n1.O=[N+]([O-])c1cccc(C=C2CCNCC2)c1>>Cc1ccc2c(OCCN3CCC(=Cc4cccc([N+](=O)[O-])c4)CC3)cccc2n1 -US20140058100A1,6,CC(=O)OCc1nc(CONC(=O)C2c3ccccc3C(=O)N(C3CCCCC3NS(C)(=O)=O)C2c2ccc(Cl)cc2Cl)no1>>CS(=O)(=O)NC1CCCCC1N1C(=O)c2ccccc2C(C(=O)NOCc2noc(CO)n2)C1c1ccc(Cl)cc1Cl -US20020143029A1,9,CCOC(=O)c1cc(Br)c(C(C)C)cc1OCC.N#C[Cu]>>CCOC(=O)c1cc(C#N)c(C(C)C)cc1OCC -US07081453B2,1,C=CCO.Oc1cnccc1Cl>>C=CCOc1cnccc1Cl -US08440664B2,6,CCOC(=O)c1sc(N2CCOC(CF)C2)c(C#N)c1-c1ccc(Cl)cc1Cl>>N#Cc1c(N2CCOC(CF)C2)sc(C(=O)O)c1-c1ccc(Cl)cc1Cl -US20100298325A1,1,OB(O)c1cccc(OCCN2CCOCC2)c1.Oc1ccc(Cl)nc1>>Clc1ccc(Oc2cccc(OCCN3CCOCC3)c2)cn1 -US05457106,2,O=C(Cl)c1ccccc1.c1ccc(CNCCCSc2ccncc2)cc1>>O=C(c1ccccc1)N(CCCSc1ccncc1)Cc1ccccc1 -US05902803,9,N.O=C(O)Cc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12>>NC(=O)Cc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12 -US04945091,1,CCCC(C)(Cl)Cn1ncc(Cl)c(Cl)c1=O.CCc1ccc(CO)cc1>>CCCC(C)(Cl)Cn1ncc(OCc2ccc(CC)cc2)c(Cl)c1=O -US05270340,6,COC(=O)C1CCC(C)=CC1NC(=O)OC(C)(C)C>>CC1=CC(NC(=O)OC(C)(C)C)C(C(=O)O)CC1 -US07705030B2,6,CCOC(=O)c1cc(C#Cc2cccc(OC)c2)cn1CC>>CCn1cc(C#Cc2cccc(OC)c2)cc1C(=O)O -US20090099183A1,1,CCOc1ccc(Br)cc1-c1cc(Cl)nc(N)n1.Nc1ccc(C(O)C(F)(F)F)cc1>>CCOc1ccc(Br)cc1-c1cc(Nc2ccc(C(O)C(F)(F)F)cc2)nc(N)n1 -US05034381,1,NCCc1cc(Br)cs1.Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>Nc1nc(NCCc2cc(Br)cs2)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O -US20110319392A1,2,CC(C)c1nc(-c2cccc(N)c2)c(-c2ccnc(Cl)n2)s1.O=S(=O)(Cl)c1cccc(F)c1>>CC(C)c1nc(-c2cccc(NS(=O)(=O)c3cccc(F)c3)c2)c(-c2ccnc(Cl)n2)s1 -US07812040B2,6,COc1cc(F)cc(Cl)c1>>Oc1cc(F)cc(Cl)c1 -US20050137243A1,2,Nc1cccc2c1cnn2CCN1CCCC1.O=C(O)Cc1cccc(Oc2ccccc2)c1>>O=C(Cc1cccc(Oc2ccccc2)c1)Nc1cccc2c1cnn2CCN1CCCC1 -US20130245000A1,1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Cl)nc2)CC1.O=C(Nc1ccc2[nH]ccc2c1)C1CC1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(-n3ccc4cc(NC(=O)C5CC5)ccc43)nc2)CC1 -US04861798,1,COc1cccc(CCCCCCCCC(=O)Cl)c1.NO>>COc1cccc(CCCCCCCCC(=O)NO)c1 -US20150175602A1,2,CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CCNC2.O=C(O)C(F)F>>CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CCN(C(=O)C(F)F)C2 -US20080188474A1,9,Clc1ncc2c(n1)-c1ccccc1CC2.NN>>NNc1ncc2c(n1)-c1ccccc1CC2 -US07618978B2,6,CCCN(C)C(=O)c1cc(C(=O)OCC)cc(-c2nc(C)no2)c1>>CCCN(C)C(=O)c1cc(C(=O)O)cc(-c2nc(C)no2)c1 -US07749998B2,9,CN(C(=O)CN1C(=O)COc2ccc(C(=O)O)cc21)C(CN1CCOCC1)c1ccc(-c2ccccc2)cc1.N>>CN(C(=O)CN1C(=O)COc2ccc(C(N)=O)cc21)C(CN1CCOCC1)c1ccc(-c2ccccc2)cc1 -US20050222139A1,2,CNCc1cccc(C(=O)N2CC(=O)Nc3ccccc32)c1.O=S(=O)(Cl)c1ccc(Br)cc1>>CN(Cc1cccc(C(=O)N2CC(=O)Nc3ccccc32)c1)S(=O)(=O)c1ccc(Br)cc1 -US08853215B2,6,CCOC(=O)CNC(=O)N1CCN(c2ccccc2C(C)(C)C)CC1>>CC(C)(C)c1ccccc1N1CCN(C(=O)NCC(=O)O)CC1 -US20100179128A1,6,CCCCn1c(=O)n(CCCc2ccccc2)c(=O)c2c1ncn2Cc1ccccc1>>CCCCn1c(=O)n(CCCc2ccccc2)c(=O)c2[nH]cnc21 -US07105567B2,2,CC(C)c1cccc(C(C)C)c1N=C=O.CCc1ccc(NCc2ccc(C(=O)N(C)C)cc2)cc1>>CCc1ccc(N(Cc2ccc(C(=O)N(C)C)cc2)C(=O)Nc2c(C(C)C)cccc2C(C)C)cc1 -US20130085138A1,2,CCOC(=O)COc1ccc2c(c1)CCC(=O)N2.NN>>NNC(=O)COc1ccc2c(c1)CCC(=O)N2 -US04957914,7,CNC(=O)C1CCc2ccccc21>>CNCC1CCc2ccccc21 -US20090023785A1,1,Cc1cccc(CCN)c1.NC(=O)c1ccc(Oc2ccc3c(c2)CCC3=O)nc1>>Cc1cccc(CCNC2CCc3cc(Oc4ccc(C(N)=O)cn4)ccc32)c1 -US08268822B2,1,CC(C)N(Cc1cccc(-c2ccnc(Cl)n2)c1)C(=O)OC(C)(C)C.NCCc1ccc(O)c(Cl)c1>>CC(C)N(Cc1cccc(-c2ccnc(NCCc3ccc(O)c(Cl)c3)n2)c1)C(=O)OC(C)(C)C -US05571923,3,CCCCCCCCCCC#Cc1ccccc1F.CN(C)C=O>>CCCCCCCCCCC#Cc1cccc(C=O)c1F -US05750471,1,BrCc1ccccc1.O=S1(=O)COc2cc(F)ccc2N1>>O=S1(=O)COc2cc(F)ccc2N1Cc1ccccc1 -US20140336503A1,1,NC1CCCCC1.O=C(NCCc1ccc(OCc2ccccc2)cc1)c1cnc(Cl)nc1Cl>>O=C(NCCc1ccc(OCc2ccccc2)cc1)c1cnc(Cl)nc1NC1CCCCC1 -US20100035918A1,1,BrCc1ccc2nonc2c1.Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)[nH]c2=O)c1>>Cc1cccc(-n2c(-c3ccc4ncnn4c3)c(C)n(Cc3ccc4nonc4c3)c2=O)c1 -US20130331382A1,1,CN1CCNCC1=O.Cn1nc(Cl)c(Cl)cc1=O>>CN1CCN(c2cc(=O)n(C)nc2Cl)CC1=O -US03978066,9,COC(=O)c1cccc2[nH]cc(C=O)c12.NO>>COC(=NO)c1cccc2[nH]cc(C=O)c12 -US08222297B2,9,COc1cccc(-c2cc(Cl)c3cc(OC)ccc3n2)c1.N>>COc1cccc(-c2cc(N)c3cc(OC)ccc3n2)c1 -US07435744B2,2,CC(C)(C)OC(=O)NCC(=O)O.Nc1cccc(NC(=O)C(=O)N2CCC(Cc3ccccc3)CC2)c1>>CC(C)(C)OC(=O)NCC(=O)Nc1cccc(NC(=O)C(=O)N2CCC(Cc3ccccc3)CC2)c1 -US04940516,1,CCCCCCCCO.O=C1c2ccc(F)cc2C(=O)c2cc3ccccc3cc21>>CCCCCCCCOc1ccc2c(c1)C(=O)c1cc3ccccc3cc1C2=O -US20040157866A1,3,COC(=O)c1ccc(N(C)C)cc1OS(=O)(=O)C(F)(F)F.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)c1ccc(N(C)C)cc1-c1ccc(C(F)(F)F)cc1 -US07498346B2,2,COc1ccc(N(Cc2cnccc2C)C2CCN([C@H](C)CCN)CC2)cc1.Cc1cc(Cl)nc(C)c1C(=O)O>>COc1ccc(N(Cc2cnccc2C)C2CCN([C@H](C)CCNC(=O)c3c(C)cc(Cl)nc3C)CC2)cc1 -US05502065,3,CCCC[Sn](CCCC)(CCCC)c1cccc(CO)c1.O=C(OCc1ccccc1)N1CCC[C@@H]1Cc1c[nH]c2ccc(Br)cc12>>O=C(OCc1ccccc1)N1CCC[C@@H]1Cc1c[nH]c2ccc(-c3cccc(CO)c3)cc12 -US20120282629A1,1,NNc1ccc(C(=O)O)cc1.O=Cc1ccc(O)c(O)c1>>O=C(O)c1ccc(NN=Cc2ccc(O)c(O)c2)cc1 -US06255333B1,6,C[Si](C)(C)C#Cc1c(C#N)nn(-c2c(Cl)cc(OC(F)(F)F)cc2Cl)c1N>>C#Cc1c(C#N)nn(-c2c(Cl)cc(OC(F)(F)F)cc2Cl)c1N -US06147088,6,Cc1cc(C)cc(-c2c(OCCC3CCCCN3C(=O)OC(C)(C)C)c3cc([N+](=O)[O-])c(Cl)cc3n(C)c2=O)c1>>Cc1cc(C)cc(-c2c(OCCC3CCCCN3)c3cc([N+](=O)[O-])c(Cl)cc3n(C)c2=O)c1 -US20110201687A1,2,CNc1cccc(C(=O)Nc2c(I)cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc2C(F)(F)F)c1F.O=C(Cl)OCC(Cl)(Cl)Cl>>CN(C(=O)OCC(Cl)(Cl)Cl)c1cccc(C(=O)Nc2c(I)cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc2C(F)(F)F)c1F -US20110237584A1,1,FC(F)(F)C(Oc1nc2ccccc2nc1Cl)c1cccnc1.NS(=O)(=O)C(F)(F)F>>O=S(=O)(Nc1nc2ccccc2nc1OC(c1cccnc1)C(F)(F)F)C(F)(F)F -US20110217311A1,6,COC(=O)c1sc2ncnc(Nc3cccnc3OC3CCC(N)CC3)c2c1C>>Cc1c(C(=O)O)sc2ncnc(Nc3cccnc3OC3CCC(N)CC3)c12 -US20150225404A1,1,Cc1ncc(-c2cc(Cl)nc3c2CCC3)cn1.OCc1cccc(F)n1>>Cc1ncc(-c2cc(OCc3cccc(F)n3)nc3c2CCC3)cn1 -US20090062348A1,6,Nc1ncccc1C(=O)NCc1cc2ccc(OCc3ccccc3)cc2o1>>Nc1ncccc1C(=O)NCc1cc2ccc(O)cc2o1 -US20050014941A1,1,CCOC(=O)CS.N#CCNC(=O)[C@@H]1CCCC[C@H]1CS(=O)(=O)c1ccc(F)cc1>>CCOC(=O)CSc1ccc(S(=O)(=O)C[C@@H]2CCCC[C@H]2C(=O)NCC#N)cc1 -US20090054427A1,2,CC(C)(C)Cc1cc(C(=O)O)no1.CC(C)(C)N>>CC(C)(C)Cc1cc(C(=O)NC(C)(C)C)no1 -US20100010037A1,1,CCN(CC)CCBr.N#Cc1cn(C(c2ccccc2)c2ccccc2)c2nc(O)cc(-c3ccccc3)c12>>CCN(CC)CCOc1cc(-c2ccccc2)c2c(C#N)cn(C(c3ccccc3)c3ccccc3)c2n1 -US20040067999A1,2,Cc1cc2c(c(C)c1N)c1ccccc1n2C(C)C.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1cc2c(c(C)c1NC(=O)Oc1ccc([N+](=O)[O-])cc1)c1ccccc1n2C(C)C -US20150087645A1,1,COc1ccc(N2CCN[C@@H](Cc3ccccc3)C2)c2ccc(C(F)(F)F)nc12.O=Cc1ncc[nH]1>>COc1ccc(N2CCN(Cc3ncc[nH]3)[C@@H](Cc3ccccc3)C2)c2ccc(C(F)(F)F)nc12 -US20090221635A1,2,Nc1ccc(O)cc1.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1Cl>>O=S(=O)(Nc1ccc(O)cc1)c1ccc(C(F)(F)F)cc1Cl -US06051712,7,CCOC(=O)CCc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc3ccccc3c2)cc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(CCCO)cc2)C(OCc2ccc3ccccc3c2)C1 -US08604038B2,1,CN.Cn1nnc(CCl)n1>>CNCc1nnn(C)n1 -US07985755B2,1,BrCc1ccccc1.Nc1nc(N)c2c(N3CCNCC3)cccc2n1>>Nc1nc(N)c2c(N3CCN(Cc4ccccc4)CC3)cccc2n1 -US07662825B2,1,COc1ccc(CO)cn1.O=S(=O)(Nc1nccnc1Cl)c1cccc(Cl)c1Cl>>COc1ccc(COc2nccnc2NS(=O)(=O)c2cccc(Cl)c2Cl)cn1 -US20040097524A1,2,CC(=O)Cl.Nc1nc(-c2ccco2)c2sccc2n1>>CC(=O)Nc1nc(-c2ccco2)c2sccc2n1 -US04258045,8,CC(=O)Nc1ccc(SCCCCl)cc1.O=C(OO)c1cccc(Cl)c1>>CC(=O)Nc1ccc(S(=O)CCCCl)cc1 -US06969711B2,8,CSc1cc(C)nc(SC)c1NC(=O)CBr.O=C(OO)c1cccc(Cl)c1>>CSc1cc(C)nc(S(C)=O)c1NC(=O)CBr -US04723991,2,Cc1nc(C)c(C#N)c(N)n1.O=C=NS(=O)(=O)c1ccccc1Cl>>Cc1nc(C)c(C#N)c(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1 -US20130078351A1,2,CCOC(=O)CCC(C)C.NCCO>>CC(C)CCC(=O)NCCO -US06080743,2,CC(=O)OC(C)=O.NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12>>CC(=O)NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12 -US20090018134A1,9,O=S(=O)(Cl)c1cccc(F)c1>>O=S([O-])c1cccc(F)c1 -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3F)cc2[nH]c1=O.COCCN>>COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3F)cc2[nH]c1=O -US20070270421A1,2,Nc1ccc(Oc2cc(NC(=O)N3CCN(CCN4CCCC4)CC3)ncn2)c(F)c1.O=C(Cc1ccccc1)N=C=S>>O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2cc(NC(=O)N3CCN(CCN4CCCC4)CC3)ncn2)c(F)c1 -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)O)CC1.O=C1CCNCCN1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N2CCNC(=O)CC2)CC1 -US20090005365A1,1,O=c1c2c[nH]c3ccc(F)nc3c-2nn1-c1ccccc1.OC1CCNCC1>>O=c1c2c[nH]c3ccc(N4CCC(O)CC4)nc3c-2nn1-c1ccccc1 -US20060264494A1,2,CC(=O)N[C@@H](CO)C(=O)O.CN[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1>>CC(=O)N[C@@H](CO)C(=O)N(C)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1 -US06858638B2,2,N#Cc1n[nH]c2ccc(N)cc12.O=S(=O)(Cl)c1cccc(F)c1>>N#Cc1n[nH]c2ccc(NS(=O)(=O)c3cccc(F)c3)cc12 -US20150246922A1,3,N#Cc1cc(Br)c2c(c1)cc1n2CCNC1=O.OB(O)c1cccc(C(F)(F)F)c1>>N#Cc1cc(-c2cccc(C(F)(F)F)c2)c2c(c1)cc1n2CCNC1=O -US05252753,4,N#Cc1ccccc1F.[N-]=[N+]=[N-]>>Fc1ccccc1-c1nnn[nH]1 -US04426381,6,CCOC(=O)c1c2n(c3cc4c(cc3c1=O)OCO4)CCS2>>O=C(O)c1c2n(c3cc4c(cc3c1=O)OCO4)CCS2 -US06878728B1,6,CC(C)CNC[C@@H](O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C>>CC(C)CNC[C@@H](O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C -US20080227724A1,2,CCCCCCCCCCCC(=O)Cl.N[C@H]1CCCNC(=O)C1>>CCCCCCCCCCCC(=O)N[C@H]1CCCNC(=O)C1 -US20100261708A1,6,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3[nH]2)CC1>>c1ccc2[nH]c(N3CCCNCC3)nc2c1 -US04681879,7,O=C(c1ccc(Cl)c(Cl)c1)N1CCC(C2Oc3ccccc3Cn3cccc32)CC1>>Clc1ccc(CN2CCC(C3Oc4ccccc4Cn4cccc43)CC2)cc1Cl -US05401851,2,CCCCCCC(C(=O)O)n1cnc([N+](=O)[O-])c1.O=C(OCc1ccccc1)[C@@H]1CCCN1>>CCCCCCC(C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1)n1cnc([N+](=O)[O-])c1 -US20140323480A1,7,O=[N+]([O-])c1ccc(N2CCOCC2)nc1NCc1cccc2ccccc12>>Nc1ccc(N2CCOCC2)nc1NCc1cccc2ccccc12 -US08258134B2,2,CC(C)(C)[Si](C)(C)OCCn1ccc(N)n1.O=C(O)C(Cc1ccccc1)n1ncc(Oc2c(F)cccc2F)cc1=O>>CC(C)(C)[Si](C)(C)OCCn1ccc(NC(=O)C(Cc2ccccc2)n2ncc(Oc3c(F)cccc3F)cc2=O)n1 -US07365085B2,6,COC(=O)C1(c2cccc(OCCCN(Cc3cccc(C(F)(F)F)c3Cl)CC(c3ccccc3)c3ccccc3)c2)CCC1>>O=C(O)C1(c2cccc(OCCCN(Cc3cccc(C(F)(F)F)c3Cl)CC(c3ccccc3)c3ccccc3)c2)CCC1 -US04973599,1,Cn1ccnc1S.O=[N+]([O-])c1cc(Cl)ccc1Cl>>Cn1ccnc1Sc1ccc(Cl)cc1[N+](=O)[O-] -US08802661B2,3,C=C(C)[C@@H]1CC[C@]2(C(=O)NCCN(C)C)CC[C@]3(C)[C@H](CCC4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.COC(=O)c1ccc(B(O)O)s1>>C=C(C)[C@@H]1CC[C@]2(C(=O)NCCN(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)s6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.NC(=O)c1nn(-c2cccc(Br)c2)c2cc(N3CC[C@@H](O)C3)ncc12>>CN1CC[C@@](O)(C#Cc2cccc(-n3nc(C(N)=O)c4cnc(N5CC[C@@H](O)C5)cc43)c2)C1=O -US04243806,7,O=C(OCc1nc2cc(CN3CCN(C(c4ccccc4)c4ccccc4)CC3)ccc2[nH]1)c1ccccc1>>OCc1nc2cc(CN3CCN(C(c4ccccc4)c4ccccc4)CC3)ccc2[nH]1 -US07001895B2,6,COc1cnn(-c2ccccc2)c(=O)c1-c1ccc(F)cc1>>O=c1c(-c2ccc(F)cc2)c(O)cnn1-c1ccccc1 -US20140343000A1,2,C=C(C)[C@@H]1CC[C@]2(NCCN3CCNCC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CN(C)C(=O)C(=O)O>>C=C(C)[C@@H]1CC[C@]2(NCCN3CCN(C(=O)C(=O)N(C)C)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US04563527,1,CS(=O)(=O)Oc1ccc2cc(C(=N)N)ccc2c1.N=C(N)NCc1ccc(C(=O)O)o1>>N=C(N)NCc1ccc(C(=O)Oc2ccc3cc(C(=N)N)ccc3c2)o1 -US20050130997A1,7,COC(=O)c1nc(-c2cccc([N+](=O)[O-])c2)n(C)c(=O)c1OC(=O)C(C)(C)C>>COC(=O)c1nc(-c2cccc(N)c2)n(C)c(=O)c1OC(=O)C(C)(C)C -US20070185092A1,1,O=C(NCc1c[nH]cn1)c1ccc(Cl)s1.O=c1ccccn1-c1ccc(I)cn1>>O=C(NCc1cn(-c2ccc(-n3ccccc3=O)nc2)cn1)c1ccc(Cl)s1 -US08461330B2,7,C=C(CCO)c1ccc2ncccc2c1>>CC(CCO)c1ccc2ncccc2c1 -US07241785B2,1,CCOC(=O)CCc1cc(O)nn1-c1ccccc1.Cc1oc(-c2ccccc2)nc1COc1cccc(CCl)c1>>CCOC(=O)CCc1cc(OCc2cccc(OCc3nc(-c4ccccc4)oc3C)c2)nn1-c1ccccc1 -US20150073146A1,1,CC1(C)O[C@H]2[C@H](N)C[C@H](OCCO)[C@H]2O1.CCCSc1nc(Cl)c(N)c(Cl)n1>>CCCSc1nc(Cl)c(N)c(N[C@@H]2C[C@H](OCCO)[C@H]3OC(C)(C)O[C@@H]23)n1 -US08269002B2,1,CS(N)(=O)=O.C[C@@H](Oc1cc(Cl)nc(SCc2cccc(F)c2F)n1)[C@@H]1COC(C)(C)O1>>C[C@@H](Oc1cc(NS(C)(=O)=O)nc(SCc2cccc(F)c2F)n1)[C@@H]1COC(C)(C)O1 -US08048893B2,6,CC1CCCCN1CCn1cc(-c2ccccc2)c(OCc2ccccc2)n1>>CC1CCCCN1CCn1cc(-c2ccccc2)c(O)n1 -US05463097,7,COCC(C)=Nc1c(C)cccc1C>>COCC(C)Nc1c(C)cccc1C -US06939882B1,1,CI.O=C(NOc1ncc(C(F)(F)F)cc1Cl)c1cccc2ccccc12>>CN(Oc1ncc(C(F)(F)F)cc1Cl)C(=O)c1cccc2ccccc12 -US20070185125A1,3,COc1ncc(Br)cc1C=O.O=C1Cc2ccccc2N1>>COc1ncc(Br)cc1C=C1C(=O)Nc2ccccc21 -US20110294781A1,1,Clc1cc(Cl)n2nc(-c3ccccc3)cc2n1.OC1CNC1>>OC1CN(c2cc(Cl)nc3cc(-c4ccccc4)nn23)C1 -US20150011773A1,3,CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(Br)cn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CC1(C)OB(/C=C/CO[Si](C)(C)C(C)(C)C)OC1(C)C>>CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(/C=C/CO[Si](C)(C)C(C)(C)C)cn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US04254122,6,CCCCNC1NC(=O)N(c2ccc(OC)cc2)C(=O)N1>>CCCCNC1NC(=O)N(c2ccc(O)cc2)C(=O)N1 -US20100249095A1,1,CC(C)(C)OC(=O)N1CCC2(CCNC2)CC1.Clc1ccncc1>>CC(C)(C)OC(=O)N1CCC2(CC1)CCN(c1ccncc1)C2 -US05059609,3,COc1ccc2c(c1)C(=O)CCO2.O=Cc1c[nH]c2ccccc12>>COc1ccc2c(c1)C(=O)C(=Cc1c[nH]c3ccccc13)CO2 -US07223769B2,10,C=C(C)COc1cc(OCC#CC)ncn1.Cl>>CC#CCOc1cc(OCC(C)(C)Cl)ncn1 -US06506747B1,3,C#C[Si](C(C)C)(C(C)C)C(C)C.Cc1cc(Br)n(-c2ccc([N+](=O)[O-])cc2)n1>>Cc1cc(C#C[Si](C(C)C)(C(C)C)C(C)C)n(-c2ccc([N+](=O)[O-])cc2)n1 -US08084485B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@@H](N)C[C@H](COCc1ccccc1)C(C)C>>CCOC(=O)[C@H](C[C@H](COCc1ccccc1)C(C)C)NC(=O)OC(C)(C)C -US08148383B2,8,CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(Cc2ccc(C(C)O)cc2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(Cc2ccc(C(C)=O)cc2)c2ncnn12 -US20040209886A1,1,CCOC(=O)c1cn2ncc(C#N)c(Cl)c2c1C.Cn1ccnc1Sc1ccc(N)cc1Cl>>CCOC(=O)c1cn2ncc(C#N)c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c2c1C -US20080027112A1,1,COc1ccc2c(Cl)cc(=O)oc2c1OC1CCCC1.Nc1ccccc1Cl>>COc1ccc2c(Nc3ccccc3Cl)cc(=O)oc2c1OC1CCCC1 -US20150232480A1,7,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc3cn2c1N1CCC(C)(CC1)OCC=CC[C@H](C)Oc1cc(C)cc(F)c1-c1cccc-3c1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc3cn2c1N1CCC(C)(CC1)OCCCC[C@H](C)Oc1cc(C)cc(F)c1-c1cccc-3c1 -US20150119396A9,3,CC(C)(C)OC(=O)NC1CCC(N(C(=O)OC(C)(C)C)[C@@H]2C[C@H]2c2cnc(Br)s2)CC1.Nc1cccc(B(O)O)c1>>CC(C)(C)OC(=O)NC1CCC(N(C(=O)OC(C)(C)C)[C@@H]2C[C@H]2c2cnc(-c3cccc(N)c3)s2)CC1 -US20120270865A2,6,CCCCCCC(Nc1ccc(C(=O)NCCC(=O)OCC)cc1)c1oc2ccc(OC)cc2c1C>>CCCCCCC(Nc1ccc(C(=O)NCCC(=O)O)cc1)c1oc2ccc(OC)cc2c1C -US20150073001A1,2,CC(=O)c1ccc(OCC2CC2)c(-c2ncnc3c(C(=O)N[C@@H]4CC[C@@H](N)CC4)c(C)[nH]c23)c1.CCC(=O)Cl>>CCC(=O)N[C@@H]1CC[C@@H](NC(=O)c2c(C)[nH]c3c(-c4cc(C(C)=O)ccc4OCC4CC4)ncnc23)CC1 -US20110301191A1,2,CC(C)(C)OC(=O)N1CCC(NCCc2ccccc2)CC1.COc1ccc(CC(=O)Cl)cc1>>COc1ccc(CC(=O)N(CCc2ccccc2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 -US07312180B2,1,Cc1cc(-n2cc(C(F)(F)F)cn2)nc(Cl)n1.Oc1ccnc(C(F)(F)F)c1>>Cc1cc(-n2cc(C(F)(F)F)cn2)nc(Oc2ccnc(C(F)(F)F)c2)n1 -US20150183801A1,3,CC1(C)OB(c2cncc(C#N)c2)OC1(C)C.O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@H](CO)C2)c(Br)c1>>N#Cc1cncc(-c2cc(C(=O)Nc3ccc(SC(F)(F)F)cc3)cnc2N2CC[C@H](CO)C2)c1 -US20130005695A1,1,CI.OC1(c2ccccc2)CCCCCC1>>COC1(c2ccccc2)CCCCCC1 -US04959361,3,C#CCN1C(=O)CN(C)C(=O)c2ccccc21.Cc1nnc2n1-c1ccc(I)cc1C(c1ccccc1F)=NC2>>Cc1nnc2n1-c1ccc(C#CCN3C(=O)CN(C)C(=O)c4ccccc43)cc1C(c1ccccc1F)=NC2 -US20020091242A1,1,CC(C)(C)OC(=O)CN(CCCBr)C(=O)C(F)(F)F.O=C(NCCCNCCCNC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)CN(CCCN(CCCNC(=O)C(F)(F)F)CCCNC(=O)C(F)(F)F)C(=O)C(F)(F)F -US20070167433A1,1,CC(C)[Si](OCC[C@H](C)OS(C)(=O)=O)(C(C)C)C(C)C.Oc1cc(F)ccc1F>>CC(C)[Si](OCC[C@@H](C)Oc1cc(F)ccc1F)(C(C)C)C(C)C -US20140128387A1,1,CI.Cc1cc2c(c([N+](=O)[O-])c1)OC(CO)C2>>COCC1Cc2cc(C)cc([N+](=O)[O-])c2O1 -US06462036B1,2,CN.O=C(O)c1ccc(-c2n[nH]c3c2Cc2ccccc2-3)cc1>>CNC(=O)c1ccc(-c2n[nH]c3c2Cc2ccccc2-3)cc1 -US20080269233A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CC[C@](O)(c2ccccc2)[C@@H](O)C1>>CC(C)(C)OC(=O)N1CC[C@](O)(c2ccccc2)[C@@H](OCc2ccccc2)C1 -US20150203511A1,6,COc1ccc(-c2nn(C)c(C)c2C)cc1C>>Cc1cc(-c2nn(C)c(C)c2C)ccc1O -US20080114061A1,3,CCOP(=O)(CC#N)OCC.CCOc1cc(C(=O)c2ccc3c(c2)OCCO3)ccc1OC>>CCOc1cc(C(=CC#N)c2ccc3c(c2)OCCO3)ccc1OC -US06605620B1,6,COc1cc(-c2cc(COC3CCN(C(=O)OCc4ccccc4)CC3)ccn2)cc(OC)c1OC>>COc1cc(-c2cc(COC3CCNCC3)ccn2)cc(OC)c1OC -US08987268B2,1,CCOC(=O)c1cc2c(Cl)c(C(N)=O)cnn2c1.C[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1N>>CCOC(=O)c1cc2c(N[C@@H]3CN(C(=O)OCc4ccccc4)C[C@@H]3C)c(C(N)=O)cnn2c1 -US06552012B2,1,Clc1cncc(Cl)c1.OCCO>>OCCOc1cncc(Cl)c1 -US20130137733A1,2,NC1CCCOC1.O=C(Cl)c1ccc2nonc2c1>>O=C(NC1CCCOC1)c1ccc2nonc2c1 -US04234490,8,CC1(C)OC[C@](C)(CCO)O1>>CC1(C)OC[C@](C)(CC=O)O1 -US20090318425A1,6,CC(C)(CO[Si](C)(C)C(C)(C)C)c1ccc(C(=O)Nc2nc3ccc(Br)nc3s2)cc1>>CC(C)(CO)c1ccc(C(=O)Nc2nc3ccc(Br)nc3s2)cc1 -US08273769B2,3,C#Cc1cc(Cl)ccc1OCC(=O)O.CC(C)(C)N1C(=O)c2ccc(Br)cc2S1(=O)=O>>CC(C)(C)N1C(=O)c2ccc(C#Cc3cc(Cl)ccc3OCC(=O)O)cc2S1(=O)=O -US20140135318A1,7,CC(C)(C)Sc1ccccc1C#N>>CC(C)(C)Sc1ccccc1CN -US06197771B1,1,Nc1c([N+](=O)[O-])cc(Br)c2c1CNCC2.O=Cc1ccc(C(F)(F)F)cc1>>Nc1c([N+](=O)[O-])cc(Br)c2c1CN(Cc1ccc(C(F)(F)F)cc1)CC2 -US20120004196A1,1,C1CC2(CCN1)OCCO2.O=[N+]([O-])c1cc(F)c(F)c(F)c1>>O=[N+]([O-])c1cc(F)c(N2CCC3(CC2)OCCO3)c(F)c1 -US20040192688A1,1,CCCN.ClCCCCOc1ccc2ccccc2c1>>CCCNCCCCOc1ccc2ccccc2c1 -US20110281854A1,1,C[C@@H]1CN[C@H](c2ccccc2)CO1.Cc1c(Br)cccc1NS(C)(=O)=O>>Cc1c(NS(C)(=O)=O)cccc1N1C[C@@H](C)OC[C@H]1c1ccccc1 -US20130274244A1,6,CC(C)(C)OC(=O)N1CCCC(Cn2ncc3c([N+](=O)[O-])cccc32)C1>>O=[N+]([O-])c1cccc2c1cnn2CC1CCCNC1 -US05192770,2,Cn1cc(C(=O)C(=O)Cl)c2ccccc21.N[C@@H]1CN2CCC1CC2>>Cn1cc(C(=O)C(=O)N[C@@H]2CN3CCC2CC3)c2ccccc21 -US20150191462A1,2,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)O.Nc1cccc(OC(F)F)n1>>CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)Nc1cccc(OC(F)F)n1 -US06977267B2,10,CCOC(=O)c1csc(C)n1.O=C1CCC(=O)N1Br>>CCOC(=O)c1csc(CBr)n1 -US20100244004A1,3,Clc1ccccn1.OB(O)c1cccc2c1oc1ccccc12>>c1ccc(-c2cccc3c2oc2ccccc23)nc1 -US20130217679A1,9,O=C1Cc2cc(S(=O)(=O)Cl)ccc2N1>>O=C1Cc2cc(S)ccc2N1 -US05726205,1,C=CCN(CC=C)Cc1ccc([C@@H]2CC[C@@H](O)CC2)cc1.O=C(O)Cc1ccc(Cl)cc1>>C=CCN(CC=C)Cc1ccc([C@@H]2CC[C@@H](OC(=O)Cc3ccc(Cl)cc3)CC2)cc1 -US06093838,6,CCOC(=O)c1ccc(N(c2cc(CC)c3c(c2)C(C)(C)CO3)C(C)C)cc1>>CCc1cc(N(c2ccc(C(=O)O)cc2)C(C)C)cc2c1OCC2(C)C -US20130281443A1,2,CN.O=C(O)c1cc(F)ccc1[N+](=O)[O-]>>CNC(=O)c1cc(F)ccc1[N+](=O)[O-] -US20050250784A1,2,COC(=O)c1cnc(N2CCN(S(=O)(=O)c3ccc(C(C)=O)cc3)CC2)s1.NO>>CC(=O)c1ccc(S(=O)(=O)N2CCN(c3ncc(C(=O)NO)s3)CC2)cc1 -US06248739B1,1,CNCC(O)c1ccc(O)cc1.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)ccc21>>CN(Cc1ccc2c(c1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C)CC(O)c1ccc(O)cc1 -US20110065760A1,2,Nc1cc(NC(=O)NC2CCCCC2)cc(Cl)c1O.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=C(Nc1cc(Cl)c(O)c(NS(=O)(=O)c2ccccc2[N+](=O)[O-])c1)NC1CCCCC1 -US06987114B1,1,CCc1c(Sc2cc(C)cc(C)c2)[nH]c(=O)[nH]c1=O.ClCc1cccnc1>>CCc1c(Sc2cc(C)cc(C)c2)n(Cc2cccnc2)c(=O)[nH]c1=O -US20060069148A1,1,CCOC(=O)CC1CCCc2c1[nH]c1c(Br)cc(F)cc21.Clc1ccc(CBr)cc1>>CCOC(=O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 -US09045486B2,6,O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(n4ccc5cccnc54)CCCC3)n2CCN1C1COC1>>O=C1c2c(O)c(=O)nc(CC3(n4ccc5cccnc54)CCCC3)n2CCN1C1COC1 -US20130296276A2,3,CCOC(=O)CP(=O)(OCC)OCC.COc1ccc(-c2ccncc2C=O)cc1>>CCOC(=O)/C=C/c1cnccc1-c1ccc(OC)cc1 -US20060122181A1,3,O=Cc1ccc(Br)s1.OCc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccc(CO)cc2)s1 -US07935699B2,2,CCNCC.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2ccn(CC(=O)O)n2)cc1Cl>>CCN(CC)C(=O)Cn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)n1 -US08106215B2,2,Cc1nc2sccn2c1C(=O)NC[C@H]1NC[C@@H]2CC(C)C[C@@H]21.Nc1nc(C(=O)O)c(-c2ccccc2)s1>>Cc1nc2sccn2c1C(=O)NC[C@@H]1[C@H]2CC(C)C[C@H]2CN1C(=O)c1nc(N)sc1-c1ccccc1 -US07666888B2,2,CCOC(=O)C1CCNCC1.O=C(O)c1ncoc1-c1ccccc1>>CCOC(=O)C1CCN(C(=O)c2ncoc2-c2ccccc2)CC1 -US20090325930A1,3,COc1ccc(C(=O)c2ccc(OCCN3CCCCC3)cc2)c(Br)c1.COc1ccc2c(c1)CCC([Sn](C)(C)C)=C2>>COc1ccc2c(c1)CCC(c1cc(OC)ccc1C(=O)c1ccc(OCCN3CCCCC3)cc1)=C2 -US05750550,1,CC(C)c1cc(O)cc2c1C(=O)N(COc1cc(C(F)(F)F)nn1-c1ccccc1)S2(=O)=O.O=C(CCCCCO)OCc1ccccc1>>CC(C)c1cc(OCCCCCC(=O)OCc2ccccc2)cc2c1C(=O)N(COc1cc(C(F)(F)F)nn1-c1ccccc1)S2(=O)=O -US20110009381A1,1,COCCN.O=C(Nc1ccccc1-c1nc2ccncc2s1)c1cc(Cl)nc(-c2ccccc2)n1>>COCCNc1cc(C(=O)Nc2ccccc2-c2nc3ccncc3s2)nc(-c2ccccc2)n1 -US20150141506A1,2,NCCO.O=C(O)c1ccc(C[C@@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@H]2O)cc1>>O=C(NCCO)c1ccc(C[C@@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@H]2O)cc1 -US20030018067A1,4,CC(C)CC(=O)c1c(-c2ccc3c(Br)c(OCC#N)ccc3c2)oc2ccccc12.[N-]=[N+]=[N-]>>CC(C)CC(=O)c1c(-c2ccc3c(Br)c(OCc4nnn[nH]4)ccc3c2)oc2ccccc12 -US20040102450A1,6,CCCC1C(=O)N(Cc2ccc3c(N)ncnc3c2)C(C)CN1C(=O)OC(C)(C)C>>CCCC1NCC(C)N(Cc2ccc3c(N)ncnc3c2)C1=O -US20090247577A1,1,BrCC=Cc1ccccc1.N#CCCNCc1ccccc1>>N#CCCN(C/C=C/c1ccccc1)Cc1ccccc1 -US20150018341A1,1,CC/C(=C(\c1ccc(O)cc1)c1ccc(Cl)nc1)c1ccccc1.CN(C)CCO>>CC/C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)nc1)c1ccccc1 -US08524917B2,2,COc1ccc2c(C(=O)O)c(C(C)C)n(Cc3ccccn3)c2c1.NCc1ccc(F)c(F)c1>>COc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccn3)c2c1 -US04331664,6,CON=C(C(=O)OC)c1cccc(O)c1>>CON=C(C(=O)O)c1cccc(O)c1 -US20050148624A1,6,COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(C(=O)NNC(=O)OC(C)(C)C)cc1>>COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(C(=O)NN)cc1 -US20020045613A1,3,COc1ccc(B(O)O)cn1.O=C(O)c1ccc(Br)s1>>COc1ccc(-c2ccc(C(=O)O)s2)cn1 -US03966820,2,CC(=O)Cl.CC(CO)c1ccc2c(=O)c3ccccc3ccc2c1>>CC(=O)OCC(C)c1ccc2c(=O)c3ccccc3ccc2c1 -US20140114068A1,7,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NS(C)(=O)=O>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NS(C)(=O)=O -US20070167436A1,2,CC(C)C(=O)Cl.CC(C)N1CCN(C(=O)[C@@H]2CC[C@@H](N)CC2)CC1>>CC(C)C(=O)N[C@@H]1CC[C@@H](C(=O)N2CCN(C(C)C)CC2)CC1 -US20090312327A1,6,CN(C(=O)OC(C)(C)C)[C@@H]1CN(C(=O)c2ccc(C#N)cc2)C[C@H]1c1ccc(Cl)c(Cl)c1>>CN[C@@H]1CN(C(=O)c2ccc(C#N)cc2)C[C@H]1c1ccc(Cl)c(Cl)c1 -US08288419B2,2,CC(F)(F)CCCCn1cc(N)cn1.COc1ccc(-c2oc(C)nc2C(=O)O)cc1>>COc1ccc(-c2oc(C)nc2C(=O)Nc2cnn(CCCCC(C)(F)F)c2)cc1 -US20050282812A1,2,CCC(CO)Nc1ccc(C(F)(F)F)cc1[N+](=O)[O-].CS(=O)(=O)Cl>>CCC(COS(C)(=O)=O)Nc1ccc(C(F)(F)F)cc1[N+](=O)[O-] -US20070032518A1,8,COC(=O)c1ccc(CO)c(N)c1>>COC(=O)c1ccc(C=O)c(N)c1 -US20080070918A1,3,N#Cc1ccc(B(O)O)cc1F.O=C1CCCc2c(Br)cccc21>>N#Cc1ccc(-c2cccc3c2CCCC3=O)cc1F -US08802679B2,2,CN(C)C(=O)Cl.CN(Cc1cccc(-c2ccc(N)cc2)c1)C(=O)CNC(=O)OC(C)(C)C>>CN(C)C(=O)Nc1ccc(-c2cccc(CN(C)C(=O)CNC(=O)OC(C)(C)C)c2)cc1 -US05780498,1,C=[N+]=[N-].O=C(O)C(=O)Cc1cccc2ccccc12>>COC(=O)C(=O)Cc1cccc2ccccc12 -US09062013B2,2,Nc1ccc(C(F)(F)F)cc1.O=C(O)[C@H]1[C@H](c2ccccc2)C12CCCC2>>O=C(Nc1ccc(C(F)(F)F)cc1)[C@H]1[C@H](c2ccccc2)C12CCCC2 -US09096600B2,1,Brc1ncnc2c1ncn2C1CCCCO1.COc1c(Br)cc(Cl)cc1C(C)N>>COc1c(Br)cc(Cl)cc1C(C)Nc1ncnc2c1ncn2C1CCCCO1 -US05985837,7,CN(C)C(=O)c1ccccc1[N+](=O)[O-]>>CN(C)C(=O)c1ccccc1N -US20100267688A1,1,Nc1ccc(C2CCC(=O)CC2)cn1.O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CNC1>>Nc1ccc(C2CCC(N3CC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cn1 -US20150005281A1,2,CCN=C=O.Cn1cc(Nc2ncc(Cl)c(NC[C@H]3CCCN3)n2)cn1>>CCNC(=O)N1CCC[C@@H]1CNc1nc(Nc2cnn(C)c2)ncc1Cl -US07285551B2,1,CCOC(=O)c1ccc2c(c1)nc(-c1ccc(O)cc1)n2C1CCCCC1.Clc1ccc(Br)c(CBr)c1>>CCOC(=O)c1ccc2c(c1)nc(-c1ccc(OCc3cc(Cl)ccc3Br)cc1)n2C1CCCCC1 -US20150148313A1,7,Cc1cc(Br)ccc1[C@H](COCc1ccccc1)C(=O)O>>Cc1cc(Br)ccc1[C@@H](CO)COCc1ccccc1 -US20130096135A1,2,CC(=O)OCC(=O)O.C[C@@H]1CNCCN1C(=O)OC(C)(C)C>>CC(=O)OCC(=O)N1CCN(C(=O)OC(C)(C)C)[C@H](C)C1 -US20060089370A1,1,FC(F)(F)Oc1ccc(CBr)cc1.N#CCc1ccc(O)cc1>>N#CCc1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 -US07569568B2,2,COC(=O)c1cn(-c2cc(C(=O)O)ccc2C)nn1.COc1c(N)cc(C(F)(F)F)cc1NS(C)(=O)=O>>COC(=O)c1cn(-c2cc(C(=O)Nc3cc(C(F)(F)F)cc(NS(C)(=O)=O)c3OC)ccc2C)nn1 -US05480902,3,CN(C)C=O.c1ccc2sccc2c1>>O=Cc1cc2ccccc2s1 -US04591585,6,CC(=O)OCC1=CC(=O)C=C2CC[C@@H]3[C@H](CC[C@]4(C)C(=O)CC[C@@H]34)[C@]21C>>C[C@]12C(CO)=CC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 -US05670514,3,CN1C(=O)CC[C@]2(C)c3ccc(Br)cc3CC[C@@H]12.OB(O)c1cccc(C(F)(F)F)c1>>CN1C(=O)CC[C@]2(C)c3ccc(-c4cccc(C(F)(F)F)c4)cc3CC[C@@H]12 -US05691349,2,CC(C)O.O=C(O)c1ccc(I)cc1>>CC(C)OC(=O)c1ccc(I)cc1 -US20030018067A1,6,CCCCC(=O)c1c(-c2ccc3cc(OC)ccc3c2)oc2ccccc12>>CCCCC(=O)c1c(-c2ccc3cc(O)ccc3c2)oc2ccccc12 -US03966824,1,COc1ccc(C(O)C(Cl)(Cl)Cl)cc1.COc1ccc(O)cc1>>COc1ccc(OC(c2ccc(OC)cc2)C(Cl)(Cl)Cl)cc1 -US20080214607A1,1,Cn1cc(-c2ccncc2)c(-c2ccc(O)cc2)n1.OCc1ccc2cccnc2n1>>Cn1cc(-c2ccncc2)c(-c2ccc(OCc3ccc4cccnc4n3)cc2)n1 -US20090023725A1,3,CS(=O)(=O)c1ccc(-n2ncc3cc(Br)ccc32)cc1.Cc1c(F)cc(C(=O)NC2CC2)cc1B(O)O>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2-c2ccc(S(C)(=O)=O)cc2)c1 -US20100004239A1,3,CCN(CC)CCN1CCc2[nH]c(C=O)c(C)c2C1=O.O=CNc1cc(F)cc2c1NC(=O)C2>>CCN(CC)CCN1CCc2[nH]c(C=C3C(=O)Nc4c(NC=O)cc(F)cc43)c(C)c2C1=O -US06506797B1,7,CCOC(=O)C(=Cc1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)OC>>CCOC(=O)C(Cc1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)OC -US05093370,1,CI.CN(C)CCCCc1ccccc1>>C[N+](C)(C)CCCCc1ccccc1 -US20070060607A1,2,CCOC(=O)c1cnc(N)c2c(COc3cccc(Nc4ccccc4)c3)csc12.NCCO>>Nc1ncc(C(=O)NCCO)c2scc(COc3cccc(Nc4ccccc4)c3)c12 -US20020045551A1,6,COC(=O)c1ccc(Cl)cc1N(C)S(C)(=O)=O>>CN(c1cc(Cl)ccc1C(=O)O)S(C)(=O)=O -US20060025445A1,2,NCC(=O)c1ccccc1.O=S(=O)(Cl)c1ccc(Cl)s1>>O=C(CNS(=O)(=O)c1ccc(Cl)s1)c1ccccc1 -US20060094767A1,1,C1CC2(CCN1)OCCO2.FC(F)(F)Oc1ccc(Br)cc1>>FC(F)(F)Oc1ccc(N2CCC3(CC2)OCCO3)cc1 -US08981084B2,2,N#Cc1ccc(C2CCNCC2)nc1.O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1>>N#Cc1ccc(C2CCN(C(=O)c3cccc(-c4noc(C(F)(F)F)n4)c3)CC2)nc1 -US04239759,7,CC(CC[N+](=O)[O-])c1ccc(-c2ccc(F)cc2)cc1>>CC(CCN)c1ccc(-c2ccc(F)cc2)cc1 -US03943124,7,COC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C>>COC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=C[C@@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C -US07572801B2,7,CCOC(=O)CCC(C)=Cc1ccc(F)cc1>>CCOC(=O)CCC(C)Cc1ccc(F)cc1 -US04309422,1,CCCSP(=O)(OCC)Oc1cccc(C=O)c1.NNC(=O)c1ccccc1>>CCCSP(=O)(OCC)Oc1cccc(C=NNC(=O)c2ccccc2)c1 -US20070293515A1,1,Cc1ccc(CC(=O)O/N=C(\N)[C@H]2CC[C@H](NC(=O)OC(C)(C)C)C2)cc1>>Cc1ccc(Cc2nc([C@H]3CC[C@H](NC(=O)OC(C)(C)C)C3)no2)cc1 -US20070027199A1,3,BrCc1cccc(Br)c1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>O=C(Cc1cccc(Br)c1)C12CC3CC(CC(C3)C1)C2 -US20150045343A1,3,CC(C)NC(=O)CC#N.O=Cc1ccc2cn[nH]c2c1>>CC(C)NC(=O)C(C#N)=Cc1ccc2cn[nH]c2c1 -US08815891B2,6,COc1cc(CN(C)C)cc2[nH]c(=O)c3c(c12)NCCC3>>CN(C)Cc1cc(O)c2c3c(c(=O)[nH]c2c1)CCCN3 -US20100048453A1,1,COC(=O)C(C)(C)Oc1ccc(OCCBr)cc1C.Nc1nc(-c2ccc(C(F)(F)F)cc2)cs1>>COC(=O)C(C)(C)Oc1ccc(OCCNc2nc(-c3ccc(C(F)(F)F)cc3)cs2)cc1C -US20120277217A1,6,CCOC(=O)c1ccccc1C(=O)COc1ccccc1-c1c[nH]cn1>>O=C(O)c1ccccc1C(=O)COc1ccccc1-c1c[nH]cn1 -US20150045339A1,6,O=C1c2ccccc2C(=O)N1CC(Nc1cccc([N+](=O)[O-])c1)C(F)(F)F>>NCC(Nc1cccc([N+](=O)[O-])c1)C(F)(F)F -US06271251B1,5,CCOC(=O)c1cc2c(Cl)c(O)cc3c2n1CCCCC3=O.COCCl>>CCOC(=O)c1cc2c(Cl)c(OCOC)cc3c2n1CCCCC3=O -US06242644B1,1,CC(C)I.CCOC(=O)C(Nc1ccc(C#N)cc1)c1ccc(O)c(SC)c1>>CCOC(=O)C(Nc1ccc(C#N)cc1)c1ccc(OC(C)C)c(SC)c1 -US04420631,2,CC(C)=CCc1ccc(C(C)C(=O)O)cc1.OCC1CCCO1>>CC(C)=CCc1ccc(C(C)C(=O)OCC2CCCO2)cc1 -US20130053563A1,2,CC(C)(O)CF.O=C(Cl)OCCl>>CC(C)(CF)OC(=O)OCCl -US20070213331A1,8,CCCN(C)C(=O)c1cc(CO)cc(C(=O)OCC)c1>>CCCN(C)C(=O)c1cc(C=O)cc(C(=O)OCC)c1 -US20100010015A1,6,COc1ccc2c(c1)C1(CCC2)CCCn2cncc21>>Oc1ccc2c(c1)C1(CCC2)CCCn2cncc21 -US08338465B2,3,CC(C)(C)c1ccc(O)c(Br)c1.O=Cc1ccc(B(O)O)o1>>CC(C)(C)c1ccc(O)c(-c2ccc(C=O)o2)c1 -US05736487,6,COC(=O)N(CCOC1CCCCO1)c1ccc(OCc2nc3ccccc3s2)cc1C>>COC(=O)N(CCO)c1ccc(OCc2nc3ccccc3s2)cc1C -US20130096118A1,6,CCOC(=O)c1ncc(-c2cccc(NC(=O)OCc3ccccc3)c2C)c2c1[nH]c1cc(OCCOC)ccc12>>COCCOc1ccc2c(c1)[nH]c1c(C(=O)O)ncc(-c3cccc(NC(=O)OCc4ccccc4)c3C)c12 -US08598173B2,2,CCOC(=O)Nc1nc2ccc(Cl)cc2nc1OC.Cc1cccc(N2CCNCC2)c1>>COc1nc2cc(Cl)ccc2nc1NC(=O)N1CCN(c2cccc(C)c2)CC1 -US05082943,1,CNc1ccccc1CCl.Sc1nc2c([nH]1)CCCC2>>CNc1ccccc1CSc1nc2c([nH]1)CCCC2 -US20150218092A1,7,O=[N+]([O-])c1ccc(OCCOC2CCCCO2)c(Br)c1>>Nc1ccc(OCCOC2CCCCO2)c(Br)c1 -US20110206607A1,3,CN(C)C=O.COc1ccc(F)cc1Cl>>COc1ccc(F)c(C=O)c1Cl -US20100197681A1,1,NC1CCCCC1.O=C(Nc1nc2cccc(Cl)n2n1)c1ccccc1>>O=C(Nc1nc2cccc(NC3CCCCC3)n2n1)c1ccccc1 -US08071592B2,7,O=[N+]([O-])c1cccc2c1OCCO2>>Nc1cccc2c1OCCO2 -US08703758B2,8,CC(C)(C)[Si](OC1CCC(CO)CC1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OC1CCC(C=O)CC1)(c1ccccc1)c1ccccc1 -US20070191388A1,1,Fc1cccc(CBr)c1.N#Cc1c(N2CCN(C(=O)c3ccco3)CC2)c2cc(Cl)cnc2[nH]c1=O>>N#Cc1c(N2CCN(C(=O)c3ccco3)CC2)c2cc(Cl)cnc2n(Cc2cccc(F)c2)c1=O -US20100317657A1,7,COC(=O)c1cc(-c2ccc3ncc4c(c3c2)n(-c2cn(C)nc2Cl)c(=O)n4C)cnc1OC>>COc1ncc(-c2ccc3ncc4c(c3c2)n(-c2cn(C)nc2Cl)c(=O)n4C)cc1CO -US08273769B2,3,COc1cccc(B(O)O)c1.CS(=O)(=O)c1cc(Br)ccc1I>>COc1cccc(-c2ccc(Br)cc2S(C)(=O)=O)c1 -US20130225591A1,1,Ic1ncn2ccsc12.NC(=O)Cc1ccc2ccccc2c1>>O=C(Cc1ccc2ccccc2c1)Nc1ncn2ccsc12 -US09040515B2,1,Cc1cc(C)c(C#N)c(O)n1.ClCc1ccccc1>>Cc1cc(C)c(C#N)c(OCc2ccccc2)n1 -US20050137398A1,1,Ic1ccc(Oc2ccccc2)cc1.O[C@H]1CN2CCC1CC2>>c1ccc(Oc2ccc(O[C@@H]3CN4CCC3CC4)cc2)cc1 -US20120309739A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncccc4c3I)cc2)CCC1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncccc4c3-c3ccccc3)cc2)CCC1 -US20110251173A1,3,C[C@@H]1CN(c2ccc(OS(=O)(=O)C(F)(F)F)c(C#N)c2)C(=O)c2c(N)ncnc2O1.OB(O)c1ccccc1Cl>>C[C@@H]1CN(c2ccc(-c3ccccc3Cl)c(C#N)c2)C(=O)c2c(N)ncnc2O1 -US08394834B2,7,CC(=O)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)cc1>>C[C@@H](O)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)cc1 -US20100227880A1,8,CN1CCN(c2ccc(-c3c(CO)nc4ccccn34)cn2)CC1>>CN1CCN(c2ccc(-c3c(C=O)nc4ccccn34)cn2)CC1 -US05753670,2,CCCCN(CC(=O)OC(C)(C)C)[C@@H]1CC[C@@H](N)CC1.N=C(NC(=O)OCc1ccccc1)c1ccc2oc(C(=O)O)cc2c1>>CCCCN(CC(=O)OC(C)(C)C)[C@@H]1CC[C@@H](NC(=O)c2cc3cc(C(=N)NC(=O)OCc4ccccc4)ccc3o2)CC1 -US04797490,7,O=[N+]([O-])c1ccc(F)c(-c2ccncc2)c1F>>Nc1ccc(F)c(-c2ccncc2)c1F -US08013166B2,3,COC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(Br)cc1.Nc1ccc(B(O)O)cc1>>COC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(N)cc2)cc1 -US04761173,2,Cc1cc(C)nc(S(=O)(=O)F)n1.Cc1cccc(Cl)c1N>>Cc1cc(C)nc(S(=O)(=O)Nc2c(C)cccc2Cl)n1 -US20100137308A1,9,COc1ccc(C(C)(C)O)c(N)c1>>COc1ccc(C(C)C)c(N)c1 -US08334287B2,3,C#Cc1cccc(C)c1.CCn1ncc(-n2cc(I)nc2C)cc1=O>>CCn1ncc(-n2cc(C#Cc3cccc(C)c3)nc2C)cc1=O -US20070219186A1,1,C1COCCN1.CCOC(=O)c1cnn2c(-c3cccc(NC(=O)c4cc(NC(=O)CCl)cc(C(F)(F)F)c4)c3)ccnc12>>CCOC(=O)c1cnn2c(-c3cccc(NC(=O)c4cc(NC(=O)CN5CCOCC5)cc(C(F)(F)F)c4)c3)ccnc12 -US07560571B2,6,CC(C)(C)OC(=O)Nc1c[nH]c(C(N)=O)c1-c1ccc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cc1>>NC(=O)c1[nH]cc(N)c1-c1ccc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cc1 -US07456162B2,1,Cc1cc(O)c(C)c(C)c1NC=O.Fc1ccc(/C=C/CBr)cc1>>Cc1cc(OC/C=C/c2ccc(F)cc2)c(C)c(C)c1NC=O -US20100227887A1,2,CCOC(=O)c1cc(C#N)cc(C)n1.Nc1ccc(Cl)cn1>>Cc1cc(C#N)cc(C(=O)Nc2ccc(Cl)cn2)n1 -US20090318690A1,6,CN(C)Cc1c(OCc2ccc(C#N)nc2)ccc2c(CCC3CCN(C(=O)OC(C)(C)C)CC3)noc12>>CN(C)Cc1c(OCc2ccc(C#N)nc2)ccc2c(CCC3CCNCC3)noc12 -US20130143892A1,1,CC(C)(C)c1noc(N2CCC(=O)CC2)n1.NC1CC1>>CC(C)(C)c1noc(N2CCC(NC3CC3)CC2)n1 -US09107916B2,1,CCc1cc(C#N)ccc1CO.COC(=O)c1ccnc(-n2nccc2O)c1>>CCc1cc(C#N)ccc1COc1ccnn1-c1cc(C(=O)OC)ccn1 -US20150284408A1,6,CC(C)(C)OC(=O)N1CCC(NCc2cccc([N+](=O)[O-])c2)CC1>>O=[N+]([O-])c1cccc(CNC2CCNCC2)c1 -US20100113435A1,2,CCOC(=O)Cc1csc(N)n1.O=S(=O)(Cl)c1c(Cl)cc(Cl)cc1Cl>>CCOC(=O)Cc1csc(NS(=O)(=O)c2c(Cl)cc(Cl)cc2Cl)n1 -US20070112047A1,9,COC(=O)c1ccc(Br)cc1F.[C-]#N>>COC(=O)c1ccc(C#N)cc1F -US06046220,9,CC1(C)CCC(C)(C)c2cc(C#CC(O)c3ccc(C(=O)O)cc3)ccc21>>CC1(C)CCC(C)(C)c2cc(C#CCc3ccc(C(=O)O)cc3)ccc21 -US08124629B2,7,CCS(=O)(=O)c1ccc(Cc2c(C)c(C(=O)OC)cc3ccc(F)cc23)cc1>>CCS(=O)(=O)c1ccc(Cc2c(C)c(CO)cc3ccc(F)cc23)cc1 -US20110015157A1,1,C[C@@H](C1CCCCC1)N1CC[C@](CCCOS(C)(=O)=O)(c2ccc(F)cc2)OC1=O.[N-]=[N+]=[N-]>>C[C@@H](C1CCCCC1)N1CC[C@](CCCN=[N+]=[N-])(c2ccc(F)cc2)OC1=O -US05428053,6,O=C(N[C@@H](CO)C(=O)Nn1cccc1)OCc1ccccc1>>N[C@@H](CO)C(=O)Nn1cccc1 -US07319104B2,1,NCCc1ccc(O)cc1.O=Cc1ccc(C(F)(F)F)cc1>>Oc1ccc(CCNCc2ccc(C(F)(F)F)cc2)cc1 -US20090018134A1,2,Cc1ccccc1S(=O)(=O)C1(c2cc(N3CCOC[C@@H]3C)nc(-c3ccc(N)cc3)n2)CC1.O=C(Cl)Oc1ccccc1>>Cc1ccccc1S(=O)(=O)C1(c2cc(N3CCOC[C@@H]3C)nc(-c3ccc(NC(=O)Oc4ccccc4)cc3)n2)CC1 -US04771054,1,CC(c1ccccc1)N1CCC(CCl)C1.CCN>>CCNCC1CCN(C(C)c2ccccc2)C1 -US08518972B2,2,COC(=O)CCC(C(N)=O)N1Cc2c(OCC3COc4ccccc4C3)cccc2C1=O>>O=C1CCC(N2Cc3c(OCC4COc5ccccc5C4)cccc3C2=O)C(=O)N1 -US08188101B2,1,C=O.c1ncc(-c2ccc(Nc3nc4c(c(NCC5CCOCC5)n3)CNCC4)cc2)o1>>CN1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(NCC3CCOCC3)c2C1 -US20110263571A1,2,CS(=O)(=O)c1cc(Br)ccc1C(=O)O.Cc1ccc(N2CCNCC2=O)c(C)c1>>Cc1ccc(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2=O)c(C)c1 -US04866091,2,CNC.O=C(Cl)c1ccc([N+](=O)[O-])c(Oc2ccc(F)cc2F)c1>>CN(C)C(=O)c1ccc([N+](=O)[O-])c(Oc2ccc(F)cc2F)c1 -US20130150326A1,1,CCCn1cc(I)cn1.CCOC(=O)Cc1cccc(Sc2c(C)[nH]c3c(F)c(Cl)ccc23)c1F>>CCCn1cc(-n2c(C)c(Sc3cccc(CC(=O)OCC)c3F)c3ccc(Cl)c(F)c32)cn1 -US20090227560A1,2,C(=C/[C@@H]1CN(Cc2ccccc2)CCN1)\c1ccccn1.COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)O)c1-c1ccccc1>>COC[C@]1(O)CCCC[C@H]1n1cnc(C(=O)N2CCN(Cc3ccccc3)CC2/C=C/c2ccccn2)c1-c1ccccc1 -US20050239781A1,7,CN(C)CCSc1c(Cl)cc2c([nH]c3cnccc32)c1[N+](=O)[O-]>>CN(C)CCSc1c(Cl)cc2c([nH]c3cnccc32)c1N -US04593104,1,Cc1cccc(C)c1N(CCl)C(=O)CCl.c1cn[nH]c1>>Cc1cccc(C)c1N(Cn1cccn1)C(=O)CCl -US07615642B2,2,CC(C)(C)c1nc2cc(S(=O)(=O)n3cc(C(=O)O)cn3)ccc2n1CC1CCOCC1.NCCO>>CC(C)(C)c1nc2cc(S(=O)(=O)n3cc(C(=O)NCCO)cn3)ccc2n1CC1CCOCC1 -US08501793B2,8,CCOC(=O)c1csc(SCCN2C(=O)OC[C@@H]2CO)n1>>CCOC(=O)c1csc(SCCN2C(=O)OC[C@@H]2C=O)n1 -US20150018363A1,1,Cn1c(C2CC2)nc2ccc(-n3ccc(Cl)cc3=O)cc21.OCc1ccc(Br)o1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(Br)o4)cc3=O)cc21 -US20110136763A1,1,CCOC(=O)CC1OB(O)c2cc(O)cc(C)c21.Clc1nsc(Cl)n1>>CCOC(=O)CC1OB(O)c2cc(Oc3nc(Cl)ns3)cc(C)c21 -USRE045670E1,2,COC(=O)CCS(=O)(=O)Cl.Cc1ccc(NC(=O)Nc2nc(CN)cs2)c(C(=O)C2CCCC2)c1>>COC(=O)CCS(=O)(=O)NCc1csc(NC(=O)Nc2ccc(C)cc2C(=O)C2CCCC2)n1 -US20130267516A1,1,COc1cc([C@@H](C)N[C@H]2CC[C@@H](c3ccc(F)nc3)C2)ccc1F.NCCO>>COc1cc([C@@H](C)N[C@H]2CC[C@@H](c3ccc(NCCO)nc3)C2)ccc1F -US20110152315A1,3,Brc1ccncc1.C#Cc1ccc(CCC(=O)OC)cc1>>COC(=O)CCc1ccc(C#Cc2ccncc2)cc1 -US20120088783A1,6,COCOc1c(C)c(C)c2c(c1C)CCC(C)(C=C(Cl)Cl)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C=C(Cl)Cl)O2 -US08344029B2,7,O=C(NCCO)/C(=C/c1ccc(C(F)(F)F)cc1)NC(=O)c1ccc(OCCC2CC2)cc1>>O=C(NC(Cc1ccc(C(F)(F)F)cc1)C(=O)NCCO)c1ccc(OCCC2CC2)cc1 -US06455521B1,1,CCOC(=O)c1c(N)sc2ccccc12.O=[N+]([O-])c1ccc(F)cc1F>>CCOC(=O)c1c(Nc2cc(F)ccc2[N+](=O)[O-])sc2ccccc12 -US20140303158A1,7,CC(C)c1nnc2c([N+](=O)[O-])cc(Br)cn12>>CC(C)c1nnc2c(N)cc(Br)cn12 -US20060079548A1,1,C[Sn](C)(C)[Sn](C)(C)C.Clc1ccnc2cc(I)sc12>>C[Sn](C)(C)c1cc2nccc(Cl)c2s1 -US06448442B1,2,CC(=O)OCC(OC(C)=O)C(OC(C)=O)C(=O)Br.CC(=O)OCc1c(I)c(N)c(I)c(C(=O)NC(COC(C)=O)C(COC(C)=O)OC(C)=O)c1I>>CC(=O)OCc1c(I)c(NC(=O)C(OC(C)=O)C(COC(C)=O)OC(C)=O)c(I)c(C(=O)NC(COC(C)=O)C(COC(C)=O)OC(C)=O)c1I -US20150111877A1,2,Cc1cccc(S(=O)(=O)N2C[C@H](NC(=O)OC(C)(C)C)Cc3ncc(N)cc32)c1.O=C(Cl)c1c(Cl)cccc1Cl>>Cc1cccc(S(=O)(=O)N2C[C@H](NC(=O)OC(C)(C)C)Cc3ncc(NC(=O)c4c(Cl)cccc4Cl)cc32)c1 -US09133148B2,1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1ccc(Br)cc1Oc1ccccc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(Br)cc2Oc2ccccc2)CC1 -US20140038941A1,2,NC1CCOCC1.O=C(O)c1ccn2c(CC3CCC(F)(F)CC3)c(C(F)(F)F)nc2c1Cl>>O=C(NC1CCOCC1)c1ccn2c(CC3CCC(F)(F)CC3)c(C(F)(F)F)nc2c1Cl -US20090149463A1,2,Cc1c(C(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCc2ccccc2)cc1.Nc1ccc(C(F)(F)F)cn1>>Cc1c(C(=O)Nc2ccc(C(F)(F)F)cn2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCc2ccccc2)cc1 -US20080280933A1,1,C=O.CC(C)(C)OC(=O)Nc1c(N)cccc1F>>CNc1cccc(F)c1NC(=O)OC(C)(C)C -US20100216746A1,3,C#CC1CC1.O=C(NCc1ccc(Cl)c(Oc2cc(Cl)cc(Br)c2)c1F)c1[nH]cnc1Cl>>O=C(NCc1ccc(Cl)c(Oc2cc(Cl)cc(C#CC3CC3)c2)c1F)c1[nH]cnc1Cl -US06562849B1,2,Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(N)cc3)cc21.S=C=Nc1cccc2ccccc12>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(NC(=S)Nc4cccc5ccccc45)cc3)cc21 -US08604024B2,7,COC(=O)C1CCCc2ccc(Br)cc2C1=O>>COC(=O)C1CCCc2ccc(Br)cc2C1O -US05747422,1,N#Cc1ccc(-c2ncc(C(F)(F)F)cc2Cl)cc1O.O=C(CBr)C1CC1>>N#Cc1ccc(-c2ncc(C(F)(F)F)cc2Cl)cc1OCC(=O)C1CC1 -US06894061B2,2,CC(C)(C)CC(=O)Cl.CCC1c2cc(F)ccc2-c2ccccc2N1S(=O)(=O)c1ccc(O)cc1>>CCC1c2cc(F)ccc2-c2ccccc2N1S(=O)(=O)c1ccc(OC(=O)CC(C)(C)C)cc1 -US07202238B2,1,C1CCNC1.O=C1CC[C@@H]2CN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3c[nH]c4ccccc34)CN2C1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1C[C@H]2CC[C@H](N3CCCC3)CN2C[C@H]1Cc1c[nH]c2ccccc12 -US07202238B2,1,C1CCNC1.O=C1CC[C@@H]2CN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3c[nH]c4ccccc34)CN2C1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1C[C@H]2CC[C@@H](N3CCCC3)CN2C[C@H]1Cc1c[nH]c2ccccc12 -US08735579B2,8,COc1c(SC)cc(C(C)(C)C)cc1[N+](=O)[O-].OO>>COc1c([N+](=O)[O-])cc(C(C)(C)C)cc1S(C)=O -US20150191419A1,1,O=C(CCCCCBr)OCc1ccccc1.O=C([O-])CCC(=O)CNC(=O)OCc1ccccc1>>O=C(CCC(=O)OCCCCCC(=O)OCc1ccccc1)CNC(=O)OCc1ccccc1 -US05998433,8,O=S(=O)(c1ccc(C(O)c2ccccc2)cc1)N1CCc2occc2C1>>O=C(c1ccccc1)c1ccc(S(=O)(=O)N2CCc3occc3C2)cc1 -US08263623B2,1,O=C1c2ccccc2C(=O)N1CCc1ccc(CCBr)cc1.OC(c1ccccc1)(c1ccccc1)c1ncn(CC2CCNCC2)n1>>O=C1c2ccccc2C(=O)N1CCc1ccc(CCN2CCC(Cn3cnc(C(O)(c4ccccc4)c4ccccc4)n3)CC2)cc1 -US07148226B2,9,Fc1cc(Br)ccc1CBr.[C-]#N>>N#CCc1ccc(Br)cc1F -US20070088071A1,1,CCCCCCC(=O)c1cc2cc(Cl)ccc2[nH]1.CI>>CCCCCCC(=O)c1cc2cc(Cl)ccc2n1C -US07888352B2,1,O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1.OC1(c2ccc(Cl)cc2)CCNCC1>>OC1(c2ccc(Cl)cc2)CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1 -US08067408B2,3,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)NCc2ccc(F)c(Br)c2)c1.O=Cc1cccc(B(O)O)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)NCc2ccc(F)c(-c3cccc(C=O)c3)c2)c1 -US20100179168A1,2,CC(C)(C)OC(=O)NC(C)(C)C(=O)O.Cc1ccc(-c2ccc(S(=O)(=O)Nc3cc(N)ccc3Cl)cc2F)o1>>Cc1ccc(-c2ccc(S(=O)(=O)Nc3cc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)ccc3Cl)cc2F)o1 -US07521462B2,6,CC(C)CN(Cc1cscn1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CN(Cc1cscn1)C1CCNCC1 -US05698702,1,ClCC=C(Cl)Cl.Oc1ccc(Sc2ccc(Cl)cc2)cc1Br>>ClC(Cl)=CCOc1ccc(Sc2ccc(Cl)cc2)cc1Br -US05631286,6,COCOC1=C(C(=O)OC)CC(C#N)(c2ccc(OC)c(OCC3CC3)c2)CC1>>COCOC1=C(C(=O)O)CC(C#N)(c2ccc(OC)c(OCC3CC3)c2)CC1 -US20080318947A1,1,CCN.O=[N+]([O-])c1cnc(Cl)cc1Cl>>CCNc1cc(Cl)ncc1[N+](=O)[O-] -US20150031674A1,8,CSc1ncc(CO)c(N)n1>>CSc1ncc(C=O)c(N)n1 -US04531964,2,CC(C)OC(=O)c1cc(N=C=S)ccc1Cl.CCOC(=O)[C@@H]1CCCN1>>CCOC(=O)C1CCCN1C(=S)Nc1ccc(Cl)c(C(=O)OC(C)C)c1 -US04394515,9,COC(=O)c1ccc2c(c1)Sc1ccccc1CC2Br>>COC(=O)c1ccc2c(c1)Sc1ccccc1CC2 -US06693101B2,7,CCCCOC(=O)CCC#Cc1ccc2c(n1)NCCO2>>CCCCOC(=O)CCCCc1ccc2c(n1)NCCO2 -US07534894B2,6,CCCCc1oc2ccccc2c1C(=O)N(C)Cc1ccc(-c2ccc(OC(Cc3ccccc3)C(=O)OC)c(Br)c2)cc1>>CCCCc1oc2ccccc2c1C(=O)N(C)Cc1ccc(-c2ccc(OC(Cc3ccccc3)C(=O)O)c(Br)c2)cc1 -US20080171754A1,1,COC(=O)c1c[nH]cn1.N#Cc1ccccc1I>>COC(=O)c1cn(-c2ccccc2C#N)cn1 -US08263606B2,3,C[Sn](C)(C)C.O=C1N(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc2C12COc1cc3c(cc12)OCCO3>>Cc1ccc2c(c1)C1(COc3cc4c(cc31)OCCO4)C(=O)N2C(c1ccccc1)c1ccccc1 -US20070049607A1,7,Cc1ccc(-c2nc(N)nc(N)c2[N+](=O)[O-])o1>>Cc1ccc(-c2nc(N)nc(N)c2N)o1 -US05866583,4,O=C(NCCc1ccccc1)c1ccccn1>>c1ccc(C2=NCCc3ccccc32)nc1 -US04992474,1,BrCCCCCBr.CCc1ccc(CCO)cc1>>CCc1ccc(CCOCCCCCBr)cc1 -US05891895,1,CC(C)(C)NN.O=C(c1cccc(Br)c1)c1c(O)ccc[n+]1[O-]>>CC(C)(C)N/N=C(/c1cccc(Br)c1)c1c(O)ccc[n+]1[O-] -US05891895,1,CC(C)(C)NN.O=C(c1cccc(Br)c1)c1c(O)ccc[n+]1[O-]>>CC(C)(C)N/N=C(\c1cccc(Br)c1)c1c(O)ccc[n+]1[O-] -US20060270666A1,2,NCc1ccc(Cl)cc1.O=C(O)c1nc2ccccc2n(-c2cccc(C(F)(F)F)c2)c1=O>>O=C(NCc1ccc(Cl)cc1)c1nc2ccccc2n(-c2cccc(C(F)(F)F)c2)c1=O -US20100063049A1,1,Cc1ncc(-c2ccnc(Cl)n2)n1C(C)C.NC1CCC(N)CC1>>Cc1ncc(-c2ccnc(NC3CCC(N)CC3)n2)n1C(C)C -US20090170803A1,1,C#CCBr.CC(C)(C)OC(=O)N1CCNCC1>>C#CCN1CCN(C(=O)OC(C)(C)C)CC1 -US08426411B2,6,CC(C)(C)OC(=O)N1CCC[C@@H](c2ncc3cnc4[nH]ccc4n23)C1>>c1cc2c(ncc3cnc([C@@H]4CCCNC4)n32)[nH]1 -US08501732B2,1,O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1cnc(Br)s1.OC1CCNCC1>>O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1cnc(N2CCC(O)CC2)s1 -US06352990B1,9,Clc1ccc(C=C(Br)Br)c(Cl)c1>>C#Cc1ccc(Cl)cc1Cl -US05646171,1,CC(C)OC(=O)OCCl.CCCc1nc(C(C)(C)O)c(C(=O)O)[nH]1>>CCCc1nc(C(C)(C)O)c(C(=O)OCOC(=O)OC(C)C)[nH]1 -US20070213355A1,7,N#CCc1ccc([N+](=O)[O-])cc1Cl>>N#CCc1ccc(N)cc1Cl -US20120264711A1,3,CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2ccc(Br)cc2)[nH]1.COC(=O)N[C@H](C(=O)N1CC2(C[C@H]1c1ncc(-c3ccc(Br)cc3)[nH]1)OCCO2)C(C)C>>COC(=O)N[C@H](C(=O)N1CC2(C[C@H]1c1ncc(-c3ccc(-c4ccc(-c5cnc([C@@H]6CCCN6C(=O)OC(C)(C)C)[nH]5)cc4)cc3)[nH]1)OCCO2)C(C)C -US08288419B2,6,COC(=O)c1ncoc1-c1cccc(C(C)(C)O[SiH2]C(C)(C)C)c1>>CC(C)(C)[SiH2]OC(C)(C)c1cccc(-c2ocnc2C(=O)O)c1 -US20150119586A1,1,CS(=O)(=O)c1ccc(Br)c(Cl)c1O.ClCCC1OCCO1>>CS(=O)(=O)c1ccc(Br)c(Cl)c1OCCC1OCCO1 -US20110112106A1,1,Brc1nccs1.Sc1ccc2c(ccc3nnc(-c4ccccc4)n32)c1>>c1ccc(-c2nnc3ccc4cc(Sc5nccs5)ccc4n23)cc1 -US20090324581A1,7,C=Cc1ccc(C(=O)OC)cc1C(F)(F)F>>CCc1ccc(C(=O)OC)cc1C(F)(F)F -US20110319439A1,1,COc1cc(Br)ccc1OCC1(O)CC(F)(F)C1.O=c1cc(/C=C/c2ccc(Cl)cc2)nc[nH]1>>COc1cc(-n2cnc(/C=C/c3ccc(Cl)cc3)cc2=O)ccc1OCC1(O)CC(F)(F)C1 -US20040176361A1,1,CN1CCNCC1.O=c1[nH]c(Cl)cc2c(Cl)cc(Cl)cc12>>CN1CCN(c2cc3c(Cl)cc(Cl)cc3c(=O)[nH]2)CC1 -US20040122244A1,7,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)N3CCCCC3)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)N3CCCCC3)c2)=C(C)C1=O -US06767909B2,1,CCBr.O=Cc1c[nH]c2ccccc12>>CCn1cc(C=O)c2ccccc21 -US05807887,8,OC(COCCCl)c1cc2ccsc2cc1F>>O=C(COCCCl)c1cc2ccsc2cc1F -US06432950B1,1,Cc1cc2c(NCc3ccc4c(c3)OCCO4)nc(Cl)nc2s1.c1cn[nH]c1>>Cc1cc2c(NCc3ccc4c(c3)OCCO4)nc(-n3cccn3)nc2s1 -US20070179165A1,1,CCCN(CCC)c1nc(C)c(N)c(OC)n1.Cc1cc(C)c(Br)c(C)c1>>CCCN(CCC)c1nc(C)c(Nc2c(C)cc(C)cc2C)c(OC)n1 -US06175007B1,1,CCON=Cc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(Cl)cc1Cl.CI>>CCON=Cc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(Cl)cc1Cl -US08349215B2,4,C=C(CC(=O)O)C(=O)O.CCCCCCCC/C=C\CCCCCCCCN>>CCCCCCCC/C=C\CCCCCCCCN1CC(C(=O)O)CC1=O -US20040204584A1,1,COc1ccc(C2COCCO2)c2sc(NC(=O)c3ccnc(Br)c3)nc12.FC1CNC1>>COc1ccc(C2COCCO2)c2sc(NC(=O)c3ccnc(N4CC(F)C4)c3)nc12 -US04916134,1,CC(C)Br.COc1ccc(N2CCN(c3ccc(-n4cn[nH]c4=O)cc3)CC2)cc1>>COc1ccc(N2CCN(c3ccc(-n4cnn(C(C)C)c4=O)cc3)CC2)cc1 -US20040102450A1,2,CC(C)(C)OC(=O)CC(=O)c1ccc(Cl)s1.CCCC1NCCN(Cc2ccc3c(N)ncnc3c2)C1=O>>CCCC1C(=O)N(Cc2ccc3c(N)ncnc3c2)CCN1C(=O)CC(=O)c1ccc(Cl)s1 -US20040024224A1,6,COC(=O)[C@@](C)(N)CSC(C)=O>>COC(=O)[C@@](C)(N)CS -US04555506,2,CC(C)C[C@@H](CP(=O)(O)CC(=O)O)NC(=O)c1ccccc1.O=C(OCc1ccccc1)[C@@H]1CCCN1>>CC(C)CC(CP(=O)(O)CC(=O)N1CCC[C@H]1C(=O)OCc1ccccc1)NC(=O)c1ccccc1 -US20110065766A1,6,CC(C)(C)OC(=O)NC12CC3CC(C1)C(C#N)C(C3)C2>>N#CC1C2CC3CC1CC(N)(C3)C2 -US20130338140A1,2,C1CCNC1.COC(=O)[C@H](C)O>>C[C@H](O)C(=O)N1CCCC1 -US20080146587A1,7,CCOC(=O)c1[nH]c2c(Br)cccc2c1C(=O)c1ccccc1>>CCOC(=O)c1[nH]c2c(Br)cccc2c1Cc1ccccc1 -US05616579,1,O=C(CCS)NC/C=C\COc1cc(CN2CCCCC2)ccn1.OCCCl>>O=C(CCSCCO)NC/C=C\COc1cc(CN2CCCCC2)ccn1 -US20090131468A1,3,NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(I)c(Br)c1.OB(O)c1cc2ccccc2o1>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(-c2cc3ccccc3o2)c(Br)c1 -US04719312,7,CCCCCCCCCCCCNC(=O)C(F)(F)F>>CCCCCCCCCCCCNCC(F)(F)F -US06552054B1,2,COc1cc(O)c2c(=O)cc(C(=O)O)oc2c1.Nc1ccc(CC2SC(=O)NC2=O)cc1>>COc1cc(O)c2c(=O)cc(C(=O)Nc3ccc(CC4SC(=O)NC4=O)cc3)oc2c1 -US20040171633A1,3,FC(F)(F)c1ccc2c(Cl)ccnc2n1.OB(O)c1cccc(-c2ccccn2)c1F>>Fc1c(-c2ccccn2)cccc1-c1ccnc2nc(C(F)(F)F)ccc12 -US20050049245A1,1,CC1(C)OCC(Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(CCl)sc32)O1.CNCC(O)c1cc2ccccc2o1>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(CC3COC(C)(C)O3)c2s1)CC(O)c1cc2ccccc2o1 -US07122545B2,2,COc1ccc(N2CCOCC2)c2sc(C(=O)O)nc12.NCC(=O)c1csc2ccccc12>>COc1ccc(N2CCOCC2)c2sc(C(=O)NCC(=O)c3csc4ccccc34)nc12 -US20080090834A1,1,Cc1ccc(-n2cc(-c3nccs3)nc2-c2ccc(I)cc2)cn1.Nc1ncccc1[N+](=O)[O-]>>Cc1ccc(-n2cc(-c3nccs3)nc2-c2ccc(Nc3ncccc3[N+](=O)[O-])cc2)cn1 -US20080090834A1,1,Cc1c[nH]cn1.Ic1ccc(-c2nc(-c3ccccn3)cn2-c2cccnc2)cc1>>Cc1cn(-c2ccc(-c3nc(-c4ccccn4)cn3-c3cccnc3)cc2)cn1 -US04377578,1,CCOC(=O)N1CCC(O)CC1.Fc1ccc(C(Br)c2ccc(F)cc2)cc1>>CCOC(=O)N1CCC(OC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 -US20140296272A1,1,COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1I)CCCC3.Sc1ccccc1>>COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1Sc1ccccc1)CCCC3 -US20070015757A1,2,COC(=O)CCN.O=C(O)c1ccc(C2C(C(=O)c3ccc(OC(F)(F)F)cc3)C2c2ccc(C3CCCCC3)cc2)cc1>>COC(=O)CCNC(=O)c1ccc(C2C(C(=O)c3ccc(OC(F)(F)F)cc3)C2c2ccc(C3CCCCC3)cc2)cc1 -US20090093518A1,6,CCOC(=O)C=Cc1ccc(Br)c(F)c1>>O=C(O)C=Cc1ccc(Br)c(F)c1 -US20050197338A1,1,CI.NC(=O)Nc1cn(-c2ccc(-c3ccccc3O)c(F)c2)nc1C(N)=O>>COc1ccccc1-c1ccc(-n2cc(NC(N)=O)c(C(N)=O)n2)cc1F -US20050176701A1,8,CC(O)c1cc(Br)ccc1Cl>>CC(=O)c1cc(Br)ccc1Cl -US20040138248A1,3,C#CCOCCn1c(CCCC)nc2cnc3ccccc3c21.Ic1ccccc1>>CCCCc1nc2cnc3ccccc3c2n1CCOCC#Cc1ccccc1 -US20130039906A1,3,Brc1cccc(Br)n1.C[Si](C)(C)CCOCn1nc([Sn](C)(C)C)c2cc(-c3cccnc3)ncc21>>C[Si](C)(C)CCOCn1nc(-c2cccc(Br)n2)c2cc(-c3cccnc3)ncc21 -US20120316147A1,2,NC1CCCOC1.O=C(O)c1cccc(-c2cccc(Cl)c2)n1>>O=C(NC1CCCOC1)c1cccc(-c2cccc(Cl)c2)n1 -US20110294781A1,1,COc1cccc(C=O)c1.NNc1cc(N2CCOCC2)n2nc(-c3ccccc3)cc2n1>>COc1cccc(C=NNc2cc(N3CCOCC3)n3nc(-c4ccccc4)cc3n2)c1 -US20140038941A1,7,CCOC(=O)/C=C/C1CCC(F)(F)CC1>>CCOC(=O)CCC1CCC(F)(F)CC1 -US20060281789A1,6,COc1cc(C=O)ccc1OCCN1CCOCC1>>O=Cc1ccc(OCCN2CCOCC2)c(O)c1 -US20150166569A1,3,C#CC(C)(C)O.NC(=O)c1nc2n(c1COc1ccccc1F)CCOc1ccc(Br)cc1-2>>CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(COc3ccccc3F)n1CCO2 -US08802864B2,2,CCC(=O)Cl.O=c1[nH]nc(C[C@@H]2CCNC2)n1-c1ccc(Br)cc1F>>CCC(=O)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(Br)cc2F)C1 -US20130196983A1,2,CCOC(=O)N1CC(C(=O)O)Oc2ccc(C#N)cc21.COC(=O)Oc1cc(N)c(Br)cc1C1CCCC1>>CCOC(=O)N1CC(C(=O)Nc2cc(OC(=O)OC)c(C3CCCC3)cc2Br)Oc2ccc(C#N)cc21 -US04256761,6,CC(=O)SCC(C)C(=O)N(CC(=O)O)C1CCC1>>CC(CS)C(=O)N(CC(=O)O)C1CCC1 -US04831179,1,N#CCBr.O=S(=O)(Cc1cccc(C(F)(F)F)c1)NC1CC1>>N#CCN(C1CC1)S(=O)(=O)Cc1cccc(C(F)(F)F)c1 -US20080119466A1,2,CCCCCCCCCCOC(=O)Cl.Nc1ccc2c(ccn2-c2ccc(NC(=O)N(O)c3ccc(Cl)c(C(F)(F)F)c3)cc2)c1>>CCCCCCCCCCOC(=O)Nc1ccc2c(ccn2-c2ccc(NC(=O)N(O)c3ccc(Cl)c(C(F)(F)F)c3)cc2)c1 -US05473071,3,C#CCCO.COC(=O)c1ccc(Br)cc1>>COC(=O)c1ccc(C#CCCO)cc1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](c2ccsc2)NC1=O.O=C(O)c1cc(-c2ccc(F)cc2)on1>>CC(C)C[C@H]1C(=O)N[C@@H](c2ccsc2)CN1C(=O)c1cc(-c2ccc(F)cc2)on1 -US20140194383A1,2,CC(C)(C)OC(=O)NCc1cccc(C2CCNCC2)c1.CC1(O)CN(c2cccc(C(=O)O)c2)CC1(C)O>>CC(C)(C)OC(=O)NCc1cccc(C2CCN(C(=O)c3cccc(N4CC(C)(O)C(C)(O)C4)c3)CC2)c1 -US20140315881A1,2,CS(=O)(=O)Cl.Cc1ccc(C(NC(=O)Cc2ccc3oc(C(N)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1>>Cc1ccc(C(NC(=O)Cc2ccc3oc(C(NS(C)(=O)=O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1 -US20050261507A1,9,O[C@H]1CO[C@H]2OCC[C@@]12Br>>O[C@H]1CO[C@H]2OCC[C@@H]12 -US08841455B2,7,COC(=O)c1ccc(C)nc1OC>>COc1nc(C)ccc1CO -US20050143426A1,1,COc1ccc(C=O)cc1-c1ccc2c(ccn2C)c1.COc1cccc([C@@H](C)N)c1>>COc1cccc([C@@H](C)NCc2ccc(OC)c(-c3ccc4c(ccn4C)c3)c2)c1 -US20150065482A1,9,CCOC(=O)c1nn(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)c2nc(C(F)(F)F)ncc12.N>>CN1CC[C@@](O)(C#Cc2cccc(-n3nc(C(N)=O)c4cnc(C(F)(F)F)nc43)c2)C1=O -US20150080365A1,1,CC(C)(C)OC(=O)N[C@H]1CCNC1.Cc1cncc(Br)c1>>Cc1cncc(N2CC[C@H](NC(=O)OC(C)(C)C)C2)c1 -US20110124642A1,2,COc1cc(CC(=O)O)cc(OC)c1.Nn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O>>COc1cc(CC(=O)Nn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)cc(OC)c1 -US07732438B2,6,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CC(F)(F)F)C1=S>>N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CC(F)(F)F)C1=S -US20140200207A1,1,C[Si](C)(C)CCOCn1cc(I)c2c(Cl)nc(Cl)nc21.OC1CCOCC1>>C[Si](C)(C)CCOCn1cc(I)c2c(OC3CCOCC3)nc(Cl)nc21 -US20110028390A1,4,Nc1cc(Br)cc(F)c1N.O=CO>>Fc1cc(Br)cc2[nH]cnc12 -US20060063940A1,3,COc1cccc(B(O)O)c1.O=[N+]([O-])c1cc(Br)ccc1F>>COc1cccc(-c2ccc(F)c([N+](=O)[O-])c2)c1 -US06197975B1,6,Cc1cc(C)cc(-c2[nH]c3ccc(O)cc3c2CCN2C(=O)c3ccccc3C2=O)c1>>Cc1cc(C)cc(-c2[nH]c3ccc(O)cc3c2CCN)c1 -US04812565,1,CN1CCC(OS(C)(=O)=O)C1.NC(=O)c1cc(F)ccc1O>>CN1CCC(Oc2ccc(F)cc2C(N)=O)C1 -US20140187553A1,2,NC1CC1.O=C(O)c1csc(Br)n1>>O=C(NC1CC1)c1csc(Br)n1 -US08518972B2,1,COC(=O)CCC(C(N)=O)N1Cc2c(O)cccc2C1=O.Cn1nc(CO)c2ccccc21>>COC(=O)CCC(C(N)=O)N1Cc2c(OCc3nn(C)c4ccccc34)cccc2C1=O -US20120322788A1,9,O=C(CCl)c1ccc(O)c2[nH]c(=O)sc12.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(=O)c1ccc(O)c2[nH]c(=O)sc12 -US20130158075A1,2,CCOC(=O)CC1CCC(c2ncc(-c3ccc(N)cc3)s2)CC1.Cc1oc(-c2ccccc2)nc1C(=O)O>>CCOC(=O)CC1CCC(c2ncc(-c3ccc(NC(=O)c4nc(-c5ccccc5)oc4C)cc3)s2)CC1 -US06599917B1,7,COCOc1ccc(N2CC[C@@H](OC(C)=O)C2=O)nc1Cc1ccccc1>>COCOc1ccc(N2CC[C@@H](O)C2=O)nc1Cc1ccccc1 -US07498353B2,6,CC(C)(C)OC(=O)NCCN(C(=O)C(Cl)Cl)c1cccc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1>>NCCN(C(=O)C(Cl)Cl)c1cccc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1 -US05109010,8,CCOC(=O)CN(C(=O)Cc1ccc(OCc2ccccc2)cc1)c1ccc(SC)cc1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)CN(C(=O)Cc1ccc(OCc2ccccc2)cc1)c1ccc(S(C)=O)cc1 -US04924010,1,C=CCBr.COC(=O)c1ccc(NC(C)=O)cc1O>>C=CCOc1cc(NC(C)=O)ccc1C(=O)OC -US20110152240A1,1,Nc1cccc(Cl)c1.O=Cc1cnn2c(NC3CC3)cc(Cl)nc12>>O=Cc1cnn2c(NC3CC3)cc(Nc3cccc(Cl)c3)nc12 -US07700808B2,2,NCc1ccccn1.O=C(O)c1ccc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)cc1>>O=C(C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(C(=O)NCc2ccccn2)cc1 -US08981084B2,2,N#Cc1cccnc1N1CCNCC1.O=C(O)c1cccc(-c2noc(C(F)(F)F)n2)c1>>N#Cc1cccnc1N1CCN(C(=O)c2cccc(-c3noc(C(F)(F)F)n3)c2)CC1 -US20110065708A1,1,CC(N)c1c(F)cc2ncccc2c1F.Nc1ncc(Br)nc1Br>>CC(Nc1nc(Br)cnc1N)c1c(F)cc2ncccc2c1F -US05439911,2,CCOC(=O)c1c(CC)ncnc1NCCc1ccc(CCO)cc1.CS(=O)(=O)Cl>>CCOC(=O)c1c(CC)ncnc1NCCc1ccc(CCOS(C)(=O)=O)cc1 -US20150203499A1,3,C#CC(=O)OC.Cc1ccc(S(=O)(=O)n2cc(I)c3c(OCC(C)C)ncnc32)cc1>>COC(=O)C#Cc1cn(S(=O)(=O)c2ccc(C)cc2)c2ncnc(OCC(C)C)c12 -US20070129416A1,2,CCOc1cc(C(C)(C)C)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1.O=C(Cl)CCc1ccccc1>>CCOc1cc(C(C)(C)C)ccc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)CCc1ccccc1 -US08153658B2,6,CCOC(=O)CCC(=O)N1CCC(CN(C(=O)OC(C)(C)C)[C@H](C)c2cccc3ccccc23)C(c2cccc(F)c2)C1>>C[C@H](c1cccc2ccccc12)N(CC1CCN(C(=O)CCC(=O)O)CC1c1cccc(F)c1)C(=O)OC(C)(C)C -US06951938B2,9,CC(=O)c1cc2c(cc1O)C1CC2CN(C(=O)C(F)(F)F)C1.NO>>CC(=NO)c1cc2c(cc1O)C1CC2CN(C(=O)C(F)(F)F)C1 -US20080076771A1,4,NC(N)=S.O=C(CCl)c1cccc(C(F)(F)F)c1F>>Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1 -US08404859B2,7,N#CCCc1cccc2[nH]ncc12>>NCCCc1cccc2[nH]ncc12 -US20090281092A1,1,CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21.Nc1cccc2c1OC(F)(F)O2>>CN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Nc3cccc4c3OC(F)(F)O4)ncc21 -US05068325,1,ClCC=Cc1ccoc1.Nc1nc2c(s1)CCNCC2>>Nc1nc2c(s1)CCN(CC=Cc1ccoc1)CC2 -US20080171771A1,1,CC(C)(C)S(N)=O.N#Cc1ccccc1C(=O)c1cccc(Br)c1>>CC(C)(C)S(=O)N=C(c1cccc(Br)c1)c1ccccc1C#N -US20130331374A1,7,CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1C(=O)O>>CC(C)(C)OC(=O)N1CC(F)(F)C[C@H]1CO -US06468979B1,8,Cc1nnsc1-c1nc(CO)cs1>>Cc1nnsc1-c1nc(C=O)cs1 -US20070287696A1,1,BrCC1CC1.CC(C)(C)OC(=O)N[C@@H]1CCC[C@H](c2ccccc2)NC1=O>>CC(C)(C)OC(=O)N[C@@H]1CCC[C@H](c2ccccc2)N(CC2CC2)C1=O -US20010031788A1,2,CCC(C(=O)Cl)c1ccccc1.CCOC(=O)CC(N)c1cccc([N+](=O)[O-])c1>>CCOC(=O)CC(NC(=O)C(CC)c1ccccc1)c1cccc([N+](=O)[O-])c1 -US08470841B2,1,CC(=O)NC(C)CCc1ccc(Oc2ccc(O)cn2)cc1.CC(C)I>>CC(=O)NC(C)CCc1ccc(Oc2ccc(OC(C)C)cn2)cc1 -US20150274704A1,6,Cn1nc(C2CC2)cc1Nc1ncc(Cl)c(NC2CC3CN(C(=O)OC(C)(C)C)CC3C2)n1>>Cn1nc(C2CC2)cc1Nc1ncc(Cl)c(NC2CC3CNCC3C2)n1 -US06057447,6,CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)CSc3ccnc4ccccc34)cc2)CC1>>O=C(CSc1ccnc2ccccc12)c1ccc(N2CCNCC2)cc1 -US05846970,1,CCOC(=O)CO.CSc1nc(Cl)c([N+](=O)[O-])c(Oc2cc(C#N)ccc2OCc2ccccc2)n1>>CCOC(=O)COc1nc(SC)nc(Oc2cc(C#N)ccc2OCc2ccccc2)c1[N+](=O)[O-] -US20110118230A1,1,BrCc1ccc(Br)cc1.O=C1CNCCN1>>O=C1CN(Cc2ccc(Br)cc2)CCN1 -US20100130492A1,2,CC(C)Cn1c(N2CCNCC2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21.C[C@@H](O)CC(=O)O>>CC(C)Cn1c(N2CCN(C(=O)C[C@@H](C)O)CC2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21 -US20100120766A1,1,Clc1nc(N2CCC2)c2nc(Cl)c(Cl)nc2n1.O[C@@H]1CCOC1>>Clc1nc(N2CCC2)c2nc(Cl)c(O[C@@H]3CCOC3)nc2n1 -US20110212940A1,3,CC(c1ccccc1)c1ccc2oc(B(O)O)cc2c1.COC(=O)C1CN(Cc2ccc(Br)c(F)c2)C1>>COC(=O)C1CN(Cc2ccc(-c3cc4cc(C(C)c5ccccc5)ccc4o3)c(F)c2)C1 -US20080058402A1,6,CCOC(=O)c1cc2c(-c3cc4ccccc4[nH]3)nn(C(C)OCC)c2s1>>CCOC(C)n1nc(-c2cc3ccccc3[nH]2)c2cc(C(=O)O)sc21 -US04699905,6,CCCCOC(=O)C(CCc1ccccc1)NC1CSC(c2cccs2)CN(CC(=O)OC(C)(C)C)C1=O>>CCCCOC(=O)C(CCc1ccccc1)NC1CSC(c2cccs2)CN(CC(=O)O)C1=O -US20060025474A1,1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(/C=C/C2(O)CCCC2)c(C)c1.CCOC(=O)CCCCCBr>>CCOC(=O)CCCCCOc1ccc(C(CC)(CC)c2ccc(/C=C/C3(O)CCCC3)c(C)c2)cc1C -US20100190725A1,2,CCN=C=O.COC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(OCc2ccccc2)c(O)c1)NC(=O)OC(C)(C)C>>CCNC(=O)Oc1cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NC(C)(C)C(=O)OC)ccc1OCc1ccccc1 -US20070270421A1,1,Cc1cc([N+](=O)[O-])ccc1O.Nc1cc(Cl)ccn1>>Cc1cc([N+](=O)[O-])ccc1Oc1ccnc(N)c1 -US20080293790A1,6,COC(=O)c1ccc(OCCCO/N=C/c2ccc(C(C)(C)C)cc2)cc1NC(=O)c1ccc(-c2ccccc2)cc1>>CC(C)(C)c1ccc(/C=N/OCCCOc2ccc(C(=O)O)c(NC(=O)c3ccc(-c4ccccc4)cc3)c2)cc1 -US20080114007A1,2,CS(=O)(=O)Cl.O=[N+]([O-])c1cccc(CCO)c1>>CS(=O)(=O)OCCc1cccc([N+](=O)[O-])c1 -US07414060B2,1,Cc1ccc(Br)c(C(=O)Nc2ccn(C)n2)n1.Nc1ccc(F)cc1>>Cc1ccc(Nc2ccc(F)cc2)c(C(=O)Nc2ccn(C)n2)n1 -US06239130B1,2,Cc1cc2c3n1C(c1ccccc1)=CN(n1c(C)nc4cc(C(=O)O)ccc4c1=O)C(=O)C3=CCC2.OCCN1CCOCC1>>Cc1cc2c3n1C(c1ccccc1)=CN(n1c(C)nc4cc(C(=O)OCCN5CCOCC5)ccc4c1=O)C(=O)C3=CCC2 -US04808605,1,CI.CN(C[C@@H]1CC[C@@H](c2nc3ccccc3[nH]2)CC1)C(=O)OCc1ccccc1>>CN(C[C@@H]1CC[C@@H](c2nc3ccccc3n2C)CC1)C(=O)OCc1ccccc1 -US20130252890A1,1,CNCCCS(=O)(=O)CCCCC(F)(F)F.Oc1ccc2c(c1)CCCC(c1cc(F)cc(F)c1)=C2CCCCCCBr>>CN(CCCCCCC1=C(c2cc(F)cc(F)c2)CCCc2cc(O)ccc21)CCCS(=O)(=O)CCCCC(F)(F)F -US06093714,3,C#CC(=O)OCC.CC(=O)Nc1ccc(C=O)c([N+](=O)[O-])c1>>CCOC(=O)C#CC(O)c1ccc(NC(C)=O)cc1[N+](=O)[O-] -US20080255114A1,7,CC(C)[C@@H]1COCC(=O)N1>>CC(C)[C@@H]1COCCN1 -US20150087826A1,6,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(NCc3ccc(F)cn3)ccc2F)CC2(CCC2)O1>>C[C@@]1(c2cc(NCc3ccc(F)cn3)ccc2F)CC2(CCC2)OC(N)=N1 -US03931407,4,Nc1cccc(C(=O)O)c1.O=C(CC1CCCCC1=O)c1ccccc1>>O=C(O)c1cccc(-n2c(-c3ccccc3)cc3c2CCCC3)c1 -US20050070506A1,3,CCCCCC[Mg+].O=Cc1cccc(Br)c1>>CCCCCCC(O)c1cccc(Br)c1 -US06803374B2,1,BrC(c1ccccc1)c1ccccc1.N#Cc1ccc2c(c1)nc(-c1ccc(O)cc1)n2C1CCCCC1>>N#Cc1ccc2c(c1)nc(-c1ccc(OC(c3ccccc3)c3ccccc3)cc1)n2C1CCCCC1 -US20130303538A1,2,CCNC(=O)CCCC(=O)O.COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1>>CCNC(=O)CCCC(=O)O[C@@]1(C#Cc2cccc(C)c2)CCC[C@@H]2[C@H]1CCN2C(=O)OC -US05015652,2,CC(C)(C)c1n[nH]c(SCCO)n1.O=C=Nc1ccc(C(F)(F)F)cc1>>CC(C)(C)c1n[nH]c(SCCOC(=O)Nc2ccc(C(F)(F)F)cc2)n1 -US20120114765A1,1,CC(Br)c1cc([N+](=O)[O-])c(Sc2ccc(Cl)cc2Cl)s1.COc1ccc(CN)cc1>>COc1ccc(CNC(C)c2cc([N+](=O)[O-])c(Sc3ccc(Cl)cc3Cl)s2)cc1 -US08293735B2,7,COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1N1CCC1>>CC(C)(C)OC(=O)N1CCC(N2CCC2)C(CO)C1 -US20070270421A1,2,CN(C)C[C@@H]1CCN(C(=O)Nc2cc(Oc3ccc(N)cc3F)ncn2)C1.O=C(Cc1ccc(F)cc1)N=C=S>>CN(C)C[C@@H]1CCN(C(=O)Nc2cc(Oc3ccc(NC(=S)NC(=O)Cc4ccc(F)cc4)cc3F)ncn2)C1 -US08680108B2,1,CC(=O)c1cc(Cl)c2cccnc2c1OS(=O)(=O)C(F)(F)F.CCC(=O)N[C@H]1CCNC1>>CCC(=O)N[C@H]1CCN(c2c(C(C)=O)cc(Cl)c3cccnc23)C1 -US20120101095A1,6,CCOC(=O)c1sc2nc(SC)nc(-c3cccc(C)n3)c2c1N>>CSc1nc(-c2cccc(C)n2)c2c(N)c(C(=O)O)sc2n1 -US05998433,1,C=CCN.O=Cc1ccoc1>>C=CCNCc1ccoc1 -US20100087427A1,6,COCCCOc1cc(C(=O)N(CC2CN(C(=O)OC(C)(C)C)CC2=O)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CNCC2=O)C(C)C)ccc1OC -US05318966,2,CC1(C)CC(=O)N(CCCCCN2CC[C@@H]3c4cccc(O)c4CC[C@@H]32)C(=O)C1.CN(C)C(=O)Cl>>CN(C)C(=O)Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCCCCN1C(=O)CC(C)(C)CC1=O -US07067534B1,4,CC(C)C(=O)Nc1cccc(C2CCN(CCCCC(=O)c3ccc(I)cc3)CC2)c1.NNc1ccccc1>>CC(C)C(=O)Nc1cccc(C2CCN(CCCc3c(-c4ccc(I)cc4)[nH]c4ccccc34)CC2)c1 -US20110224193A1,2,O=C(Nc1ccc(N2CC3CC2CN3)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F.O=C=Nc1ccccc1Cl>>O=C(Nc1ccc(N2CC3CC2CN3C(=O)Nc2ccccc2Cl)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F -US20120077793A1,6,CC(C)OC(=O)N1CCC(Oc2ccc(-c3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N4CCC(F)(F)C4)c(F)c3)cn2)CC1>>CC(C)OC(=O)N1CCC(Oc2ccc(-c3ccc(C[C@H](N)C(=O)N4CCC(F)(F)C4)c(F)c3)cn2)CC1 -US20150005275A1,2,CC(=O)Cl.NC(=O)c1ccsc1N>>CC(=O)Nc1sccc1C(N)=O -US06884868B1,1,CC(=O)N1CCN(c2ccc(O)cc2)CC1.OCCCBr>>CC(=O)N1CCN(c2ccc(OCCCO)cc2)CC1 -US08933105B2,2,CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccsc1>>CN(Cc1cn(S(=O)(=O)c2ccsc2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C -US04518597,8,COc1ccc(SCCCOc2ccc3c(c2)C(C(C)C)OC(=O)N3)cc1OC.OO>>COc1ccc(S(=O)CCCOc2ccc3c(c2)C(C(C)C)OC(=O)N3)cc1OC -US08193202B2,2,COc1cccc(N)c1.Cc1c[nH]c2ncnc(N3CCC(C)(C(=O)O)CC3)c12>>COc1cccc(NC(=O)C2(C)CCN(c3ncnc4[nH]cc(C)c34)CC2)c1 -US20080269267A1,3,CCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Nc1ccc(Oc2ccnc(Cl)c2)cc1F>>CCCn1cc(-c2cc(Oc3ccc(N)c(F)c3)ccn2)cn1 -USRE045183E1,1,CCOC(=O)Cc1ccc(N)cc1.O=Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1>>CCOC(=O)Cc1ccc(NCc2cnc(NC(=O)N(C3CCCCC3)C3CCCCC3)s2)cc1 -US08426447B2,3,C#CC1CC1.NC1=N[C@]2(CO1)c1cc(O)ccc1Oc1ccc(Br)cc12>>NC1=N[C@]2(CO1)c1cc(O)ccc1Oc1ccc(C#CC3CC3)cc12 -US20150210682A1,4,COCCCOc1cc(CC(NC=O)C2CCC2)ccc1OC>>COCCCOc1cc2c(cc1OC)C=NC(C1CCC1)C2 -US20100273744A1,3,C[Zn+].O=C(Nc1ccn(Cc2ccc(I)cc2C(F)(F)F)n1)c1c(F)cccc1F>>Cc1ccc(Cn2ccc(NC(=O)c3c(F)cccc3F)n2)c(C(F)(F)F)c1 -US06342503B1,6,CCN(c1nc(C)cc(C(=O)N2CCC3(CC2)OCCO3)n1)c1ccc(C(C)C)cc1Br>>CCN(c1nc(C)cc(C(=O)N2CCC(=O)CC2)n1)c1ccc(C(C)C)cc1Br -US20020193402A1,6,Cc1nnnn1[C@@H]1C[C@@]2(c3ccccc3)[C@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC[C@@H]1N2Cc1ccccc1>>Cc1nnnn1[C@@H]1C[C@]2(c3ccccc3)N[C@H]1CC[C@H]2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US07786113B2,4,Nc1cc([N+](=O)[O-])cnc1N.O=C(O)c1ccnc(Cl)c1>>O=[N+]([O-])c1cnc2[nH]c(-c3ccnc(Cl)c3)nc2c1 -US07781591B2,1,COc1ccc(-c2cncc(C#N)c2Cl)cc1OC.Cc1ccc(N)c2[nH]ccc12>>COc1ccc(-c2cncc(C#N)c2Nc2ccc(C)c3cc[nH]c23)cc1OC -US20100240642A1,1,CCOC(=O)c1[nH]c2ccccc2c1-c1ccc(C(C)(C)C)cc1.COCCOc1cc(CCl)cc(OCCOC)c1>>CCOC(=O)c1c(-c2ccc(C(C)(C)C)cc2)c2ccccc2n1Cc1cc(OCCOC)cc(OCCOC)c1 -US20150031668A1,1,CC(C)(C)[S@](N)=O.O=C(c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1Br>>CC(C)(C)[S@@](=O)/N=C(\c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1Br -US20150018363A1,1,CCc1nc2ccc(-n3ccc(O)cc3=O)cc2n1C.OCc1ccc(Cl)c(F)c1>>CCc1nc2ccc(-n3ccc(OCc4ccc(Cl)c(F)c4)cc3=O)cc2n1C -US07326791B2,6,C[C@H](NC(=O)c1ccc(C(=O)N2CCC[C@H]2CNC(=O)OC(C)(C)C)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1>>C[C@H](NC(=O)c1ccc(C(=O)N2CCC[C@H]2CN)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1 -US07919510B2,1,CCN(CC)CCN.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>CCN(CC)CCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] -US20140350019A1,7,Cc1ccc(-c2cccc(F)c2)cc1C(=O)Nc1c(F)ccc(O)c1F>>Cc1ccc(-c2cccc(F)c2)cc1CNc1c(F)ccc(O)c1F -US20060069144A1,7,C=C(c1c[nH]cn1)c1cccc2cccnc12>>CC(c1c[nH]cn1)c1cccc2cccnc12 -US20060135554A1,7,CCOc1ccc(Cc2nc3cc([N+](=O)[O-])cnc3n2CC2CC2)cc1>>CCOc1ccc(Cc2nc3cc(N)cnc3n2CC2CC2)cc1 -US04689342,8,Cc1c(CO)cccc1-n1cccc1>>Cc1c(C=O)cccc1-n1cccc1 -US06025375,1,CCOC(=O)CBr.Oc1cccc(CC2CCCC=C2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1>>CCOC(=O)COc1cccc(CC2CCCC=C2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 -US20130210803A1,7,O=C1Nc2ccccc2SC1c1ccncc1>>c1ccc2c(c1)NCC(c1ccncc1)S2 -US06265575B1,3,C#CCO.O=C(c1ccc(I)cc1)c1c(-c2ccc(OCCN3CCCC3)cc2)sc2ccccc12>>O=C(c1ccc(C#CCO)cc1)c1c(-c2ccc(OCCN3CCCC3)cc2)sc2ccccc12 -US20090281060A1,6,COC(=O)C1CCC(c2nc(-c3ccncc3)no2)CC1>>O=C(O)[C@@H]1CC[C@@H](c2nc(-c3ccncc3)no2)CC1 -US06946491B2,1,O=C(CBr)c1ccc(OCc2c(F)cccc2F)cc1.Sc1nc[nH]n1>>O=C(CSc1nc[nH]n1)c1ccc(OCc2c(F)cccc2F)cc1 -US20090318431A1,1,CI.O=C1Nc2ccc([N+](=O)[O-])cc2CO1>>CN1C(=O)OCc2cc([N+](=O)[O-])ccc21 -US20120142659A1,7,CC(C)[C@@H](COC(=O)c1ccc(Cl)cc1)N(C)C(=O)c1ccc(Cl)cc1>>CC(C)[C@@H](CO)N(C)C(=O)c1ccc(Cl)cc1 -US06080754,1,BrCc1ccccc1.CCCc1ccc(O)cn1>>CCCc1ccc(OCc2ccccc2)cn1 -US07951815B2,1,CC(=O)N1CCC2(CC1)NC(=O)[C@H](Cc1ccccc1)N2.ClCc1ccccc1>>CC(=O)N1CCC2(CC1)N[C@@H](Cc1ccccc1)C(=O)N2Cc1ccccc1 -US07511037B2,3,CC1(C)OCCn2c1nc(C(=O)NCc1ccc(F)cc1I)c(OCc1ccccc1)c2=O.OB(O)c1ccn[nH]1>>CC1(C)OCCn2c1nc(C(=O)NCc1ccc(F)cc1-c1ccn[nH]1)c(OCc1ccccc1)c2=O -US20150141464A1,6,COC(=O)c1ncccc1-c1ccc(Cn2cnc3cc(C(=O)N[C@@H](C)c4cccc(C(C)C)c4)ccc32)cc1>>CC(C)c1cccc([C@H](C)NC(=O)c2ccc3c(c2)ncn3Cc2ccc(-c3cccnc3C(=O)O)cc2)c1 -US07615634B2,1,CC[C@@H](N)CO.COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N>>CC[C@H](CO)NCCCS(=O)(=O)N1CCC(Nc2ncc(C(=O)c3c(OC)ccc(F)c3F)c(N)n2)CC1 -US05854228,1,BrCc1ccccc1.CC1(C)OCC(CO)CO1>>CC1(C)OCC(COCc2ccccc2)CO1 -US20090318467A1,6,COc1ncc(-c2nc(C(=O)N3CCC(N4CCCC4)CC3)c(C)cc2-c2cccc(C(F)(F)F)c2)cn1>>Cc1cc(-c2cccc(C(F)(F)F)c2)c(-c2cnc(O)nc2)nc1C(=O)N1CCC(N2CCCC2)CC1 -US08063071B2,1,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(C=O)c4)cc23)CC1.COCCNCCOC>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CN(CCOC)CCOC)c4)cc23)CC1 -US04801705,6,O=C(N[C@H]1CN(C(=O)NS(=O)(=O)Nc2cc(O)c(O)cc2C(=O)O)C1=O)OCc1ccccc1>>N[C@H]1CN(C(=O)NS(=O)(=O)Nc2cc(O)c(O)cc2C(=O)O)C1=O -US20140249244A1,1,COC(=O)/C(C#N)=C/c1ccc(O)cc1.OCCCCCCCl>>COC(=O)/C(C#N)=C/c1ccc(OCCCCCCO)cc1 -US20090088368A1,2,COC(=O)Cc1ccc(C)c(S(=O)(=O)Cl)c1.FC(F)(F)c1ccc(-c2nc3c(s2)CNCC3)cc1>>COC(=O)Cc1ccc(C)c(S(=O)(=O)N2CCc3nc(-c4ccc(C(F)(F)F)cc4)sc3C2)c1 -US20120232056A1,6,COC(=O)c1ccc2nc(-c3ccc(F)cc3C)c(N(C)C(C)C)nc2c1>>Cc1cc(F)ccc1-c1nc2ccc(C(=O)O)cc2nc1N(C)C(C)C -US06812331B2,1,CO[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)OC1(C)C.Cc1c(O)ccc2c(OCc3ccccc3)c(C(=O)OCC(C)C)c(=O)oc12>>CO[C@@H]1[C@@H](O)[C@@H](O)[C@H](Oc2ccc3c(OCc4ccccc4)c(C(=O)OCC(C)C)c(=O)oc3c2C)OC1(C)C -US06005106,1,COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(Br)c2)c1C(=O)OC.O=C1CCc2ccccc2N1>>COC(=O)c1cc2cc(OC)c(OC)cc2c(-c2ccnc(N3C(=O)CCc4ccccc43)c2)c1C(=O)OC -US20080249308A1,7,O=C(c1ccccc1)c1ccccc1>>OC(c1ccccc1)c1ccccc1 -US20110039824A1,1,CI.CN(C)Cc1c[nH]c2cc(F)ccc12>>C[N+](C)(C)Cc1c[nH]c2cc(F)ccc12 -US09115072B2,1,CCOC(=O)Cc1ccc(C)c(O)c1.Cc1cccc(C)c1CCl>>CCOC(=O)Cc1ccc(C)c(OCc2c(C)cccc2C)c1 -US20110110889A1,3,C#Cc1ccccc1.Nc1ncc([N+](=O)[O-])cc1Br>>Nc1ncc([N+](=O)[O-])cc1C#Cc1ccccc1 -US20130184476A1,7,CCCCC(F)(F)C(=O)CC[C@H]1[C@H](OC2CCCCO2)C[C@@H]2OC(=O)C[C@@H]21>>CCCCC(F)(F)C(O)CC[C@H]1[C@H](OC2CCCCO2)C[C@@H]2OC(=O)C[C@@H]21 -US05624943,1,CI.Cc1ccc(O)c(I)n1>>COc1ccc(C)nc1I -US20090048248A1,2,Cc1ccccc1[C@@H]1[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC[C@@H]2CNC[C@H]21.O=C(O)c1ccon1>>Cc1ccccc1[C@@H]1[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC[C@@H]2CN(C(=O)c3ccon3)C[C@H]21 -US05334225,6,Cc1ccc(NC(=O)CCNC(=O)OC(C)(C)C)c(O)c1>>Cc1ccc(NC(=O)CCN)c(O)c1 -US20120241794A1,3,Clc1cc(Cl)ncn1.OB(O)c1ccccc1>>Clc1cc(-c2ccccc2)ncn1 -US20110112120A9,6,CCCCc1nc(C)n(CC(=O)OCC)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1>>CCCCc1nc(C)n(CC(=O)O)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1 -US04582833,6,O=C(OCc1ccccc1)N1CCN(c2nc3nccc(-c4cccnc4)n3n2)CC1>>c1cncc(-c2ccnc3nc(N4CCNCC4)nn23)c1 -US20020193367A1,2,COCCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl.Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)on1>>COCCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cc(C)no3)c2)cc1Cl -US20130136719A1,6,COC(=O)c1sc(C#CC(C)(C)C)cc1N(C(=O)c1ccc(C)cc1C)[C@@H]1CC[C@@H](O)CC1>>Cc1ccc(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)[C@@H]2CC[C@@H](O)CC2)c(C)c1 -US20150038574A1,7,CC1=C(C=O)C(C)(C)CCC1>>CC1=C(CO)C(C)(C)CCC1 -US05608056,6,CC(C)(C)[Si](C)(C)O[C@@H]1C[C@@H](/C=C\c2cccnc2)N(C(=O)OCc2ccccc2)C1>>O=C(OCc1ccccc1)N1C[C@H](O)C[C@H]1/C=C\c1cccnc1 -US07666888B2,2,Cc1ccc(-c2oncc2C(=O)O)cc1.FC1(F)CCCNC1>>Cc1ccc(-c2oncc2C(=O)N2CCCC(F)(F)C2)cc1 -US20110275637A1,7,COC(=O)c1cccnc1C>>Cc1ncccc1CO -US20040248872A1,7,COC(=O)CCCC(C)=C(F)F>>CC(CCCCO)=C(F)F -US05952362,6,CC(=O)Nc1c(C)cc([N+](=O)[O-])c(C)c1[N+](=O)[O-]>>Cc1cc([N+](=O)[O-])c(C)c([N+](=O)[O-])c1N -US07595327B2,6,CCOC(=O)C1CN(C(C)=O)CCC1NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1>>CC(=O)N1CCC(NS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(C(=O)O)C1 -US05401848,2,CC1(C)c2ccc([N+](=O)[O-])cc2[C@@H](N)[C@@H]1O.O=C=Nc1ccccc1>>CC1(C)c2ccc([N+](=O)[O-])cc2[C@@H](NC(=O)Nc2ccccc2)[C@@H]1O -US05958918,1,CC(C)(C)OC(=O)CBr.COc1ccc2ccc(S(=O)(=O)N[C@H]3CCN(Cc4ccnc(C#N)c4)C3=O)cc2c1>>COc1ccc2ccc(S(=O)(=O)N(CC(=O)OC(C)(C)C)[C@H]3CCN(Cc4ccnc(C#N)c4)C3=O)cc2c1 -US20030055087A1,1,C[O-].O=[N+]([O-])c1ccc2ccnc(Cl)c2c1>>COc1nccc2ccc([N+](=O)[O-])cc12 -US20150018363A1,1,Cc1nc2ccc(Br)cc2n1C.O=c1cc(OCc2ccc(F)cc2)cc[nH]1>>Cc1nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc2n1C -US06420375B1,3,CC(=O)c1ccc2cc(C)ccc2c1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C(\C)c1ccc2cc(C)ccc2c1 -US20020038025A1,1,CN(C(=O)OC(C)(C)C)c1ccc(C#CCCCOS(C)(=O)=O)cc1.CNC>>CN(C)CCCC#Cc1ccc(N(C)C(=O)OC(C)(C)C)cc1 -US20100323994A1,2,CC(C)n1ccc(Nc2cc(N[C@@H]3CC[C@@H](N)CC3)nn3c(C(=O)Nc4ccncc4F)cnc23)n1.N#CCC(=O)O>>CC(C)n1ccc(Nc2cc(N[C@@H]3CC[C@@H](NC(=O)CC#N)CC3)nn3c(C(=O)Nc4ccncc4F)cnc23)n1 -US06217793B1,1,CCCCCCCCCCCCC(=O)Oc1ccc(C(=O)O)cc1.Oc1ccc(OCc2ccccc2)cc1>>CCCCCCCCCCCCC(=O)Oc1ccc(C(=O)Oc2ccc(OCc3ccccc3)cc2)cc1 -US20150080549A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)SSC(CN=[N+]=[N-])C[C@H](N)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](CC(CN=[N+]=[N-])SSC(C)(C)C)C(=O)O -US07994324B2,7,O=[N+]([O-])c1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12>>Nc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12 -US07888349B2,1,CC(C)(C)OC(=O)NCCCn1c(CCl)nc2cnc3cc(OCc4ccccc4)ccc3c21>>CC(C)(C)OC(=O)N1CCCn2c(nc3cnc4cc(OCc5ccccc5)ccc4c32)C1 -US20100120739A1,7,C=Cc1cnc2ccc(Cc3nnc4ccc(C)nn34)cc2c1>>CCc1cnc2ccc(Cc3nnc4ccc(C)nn34)cc2c1 -US05241107,1,BrCc1ccccc1.Oc1ccc2ccc3cccc4ccc1c2c34>>c1ccc(COc2ccc3ccc4cccc5ccc2c3c45)cc1 -US05063246,8,CCOc1ccccc1OCCNC(C)Cc1ccc(OC)c(SC)c1.OO>>CCOc1ccccc1OCCNC(C)Cc1ccc(OC)c(S(C)=O)c1 -US20100003305A1,6,COC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(C)C)C(C)C>>CC(C)[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(C)C)C(=O)NCC(=O)O -US06245790B1,6,COc1cccc(CC2CCCC=C2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1C>>Cc1c(O)cccc1CC1CCCC=C1c1nc(-c2ccccc2)c(-c2ccccc2)o1 -US20100120784A1,1,CC(C)(C)OC(=O)NCCCBr.Oc1cc(F)ccc1Br>>CC(C)(C)OC(=O)NCCCOc1cc(F)ccc1Br -US20040018192A1,2,Nc1cccc2c(Cl)c[nH]c12.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>O=C(O)c1ccc(S(=O)(=O)Nc2cccc3c(Cl)c[nH]c23)cc1 -US04711890,6,CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1cc(-c2ccccc2)nc2ccccc12>>CCN(CC1CCNCC1)C(=O)c1cc(-c2ccccc2)nc2ccccc12 -US20060189661A1,6,COC(=O)c1cc(Br)cc(-c2cccnc2)c1>>O=C(O)c1cc(Br)cc(-c2cccnc2)c1 -US07625948B2,2,CCOC(=O)C(CO)(C(=O)OCC)c1ccccc1.Cc1cc(CC(=O)O)ccc1[N+](=O)[O-]>>CCOC(=O)C(COC(=O)Cc1ccc([N+](=O)[O-])c(C)c1)(C(=O)OCC)c1ccccc1 -US04409017,6,COc1ccc(Nc2nc(Cl)cc3ccccc23)cc1>>Oc1ccc(Nc2nc(Cl)cc3ccccc23)cc1 -US20040157891A1,1,COc1ccc(-c2nc(OC)oc2-c2ccc(OCCOS(C)(=O)=O)cc2)cc1.O=C1NC(=O)c2ccccc21>>COc1ccc(-c2nc(OC)oc2-c2ccc(OCCN3C(=O)c4ccccc4C3=O)cc2)cc1 -US20130236434A1,1,Nc1ccccc1.O=Cc1cccs1>>c1ccc(NCc2cccs2)cc1 -US20030153753A1,6,Cc1ccc(C[C@@H]2CN(Cc3ccccc3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1O>>Cc1ccc(C[C@@H]2CNCCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1O -US08791257B2,6,CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](O)CC1>>N[C@@H]1CCC[C@H](O)CC1 -US20100144786A1,4,CCOC(=O)C(Cc1cccc(S(C)(=O)=O)c1)C(=O)CC.COC(=O)COc1ccc(F)c(N)c1>>CCc1[nH]c2c(F)ccc(OCC(=O)OC)c2c(=O)c1Cc1cccc(S(C)(=O)=O)c1 -US20040092507A1,1,C1CNCCN1.CC(C)c1ccccc1Br>>CC(C)c1ccccc1N1CCNCC1 -US20070027303A1,6,CC(C)(C)OC(=O)C(NC(=O)CCCC(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)C(NC(=O)CCCC(=O)O)C(=O)OC(C)(C)C -US08071592B2,6,COc1cnc2ccc(=O)n(CCN3C[C@H](O)[C@H](CNC(=O)OCc4ccccc4)C3)c2c1>>COc1cnc2ccc(=O)n(CCN3C[C@H](O)[C@H](CN)C3)c2c1 -US20090124796A1,3,FC(F)(F)I.O=c1cc[nH]c(=O)[nH]1>>O=c1[nH]cc(C(F)(F)F)c(=O)[nH]1 -US07259163B2,6,CC(C)C[C@@]1(C(=O)OC(C)(C)C)C[C@H](c2cnccn2)[C@H](c2cccc(-c3ccccc3)c2)N1C(=O)c1ccc(C(C)(C)C)cc1>>CC(C)C[C@@]1(C(=O)O)C[C@H](c2cnccn2)[C@H](c2cccc(-c3ccccc3)c2)N1C(=O)c1ccc(C(C)(C)C)cc1 -US07253198B2,7,C[C@H](NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(N2CCCC2=O)cc([N+](=O)[O-])c1)C(=O)NC1CCCCC1>>C[C@H](NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(N)cc(N2CCCC2=O)c1)C(=O)NC1CCCCC1 -US20090023725A1,3,Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1.Fc1ccc(-c2n[nH]c3cc(Br)ccc23)cc1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(-c3ccc(F)cc3)n[nH]c2c1 -US20060229312A1,7,Cc1ccc2c(N3CCN(CC(C)c4cccc([N+](=O)[O-])c4)CC3)cccc2n1>>Cc1ccc2c(N3CCN(CC(C)c4cccc(N)c4)CC3)cccc2n1 -US20120142752A1,6,COC(=O)N[C@H](C(=O)NCCN(C)[C@@H]1CN(Cc2ccccc2)C[C@H]1N(CCC(C)C)S(=O)(=O)c1ccc([N+](=O)[O-])cc1)C(c1ccccc1)c1ccccc1>>COC(=O)N[C@H](C(=O)NCCN(C)[C@@H]1CNC[C@H]1N(CCC(C)C)S(=O)(=O)c1ccc([N+](=O)[O-])cc1)C(c1ccccc1)c1ccccc1 -US20030092694A1,1,BrCc1ccccc1.C[C@H]1CNC[C@@H](C)N1>>C[C@H]1CN(Cc2ccccc2)C[C@@H](C)N1 -US07226931B2,6,Cc1c(N2CCC(C3(N(C)C4CCN(C(=O)OC(C)(C)C)CC4)CC3)C2)c(F)cn2c(=O)c(C(=O)O)cc(C3CC3)c12>>Cc1c(N2CCC(C3(N(C)C4CCNCC4)CC3)C2)c(F)cn2c(=O)c(C(=O)O)cc(C3CC3)c12 -US20090143385A1,1,Cc1onc(-c2cccc(F)c2)c1CO.Clc1ccc(Cl)nn1>>Cc1onc(-c2cccc(F)c2)c1COc1ccc(Cl)nn1 -US08822497B2,2,CC(C)(C)OC(=O)NC1CCCN(c2ccc(C(=O)c3ccccc3)cc2N)C1.Nc1ncc(Br)nc1C(=O)O>>CC(C)(C)OC(=O)NC1CCCN(c2ccc(C(=O)c3ccccc3)cc2NC(=O)c2nc(Br)cnc2N)C1 -US07750038B2,2,CCS(=O)(=O)Cl.Fc1cc(Br)cc2c1NCC2>>CCS(=O)(=O)N1CCc2cc(Br)cc(F)c21 -US20130196971A1,7,CC(C)(C)OC(=O)N1CC[C@@H](C#N)C1>>CC(C)(C)OC(=O)N1CC[C@@H](CN)C1 -US08183262B2,1,Cc1cc(-c2ccc(Cl)c(C)c2)nc(Cl)n1.Ic1c[nH]cn1>>Cc1cc(-c2ccc(Cl)c(C)c2)nc(-n2cnc(I)c2)n1 -US20080287431A1,1,COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)cc(Cl)n1.C[C@H]1CNC[C@@H](C)O1>>COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)cc(N2C[C@H](C)O[C@H](C)C2)n1 -US20130338142A1,3,CC1(C)OB(c2cnc3c(c2)NCCO3)OC1(C)C.COc1cc(Nc2nc(Br)cn3ccnc23)ccc1N1CCOCC1>>COc1cc(Nc2nc(-c3cnc4c(c3)NCCO4)cn3ccnc23)ccc1N1CCOCC1 -US20080051398A1,1,C1COCCN1.COc1ccc(N(C)c2nc(Cl)nc3ccccc23)cc1>>COc1ccc(N(C)c2nc(N3CCOCC3)nc3ccccc23)cc1 -US20150266857A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSCCc1nc2cc(-c3c[nH]c4cc(F)ccc34)ccc2o1>>CSCCc1nc2cc(-c3cn(C(=O)OC(C)(C)C)c4cc(F)ccc34)ccc2o1 -US20140213571A1,3,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(B3OC(C)(C)C(C)(C)O3)cc12.Fc1cccc2[nH]c3c(c12)C(c1cccs1)Oc1ccc(Cl)nc1-3>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3[nH]c5cccc(F)c5c3C(c3cccs3)O4)cc12 -US20090227799A1,2,NCc1cccc(Oc2ccccc2)c1.O=C(Cl)Oc1ccccc1>>O=C(NCc1cccc(Oc2ccccc2)c1)Oc1ccccc1 -US20100063067A1,1,COc1cc(N2CCC(C(=O)Cn3nc(C(F)(F)F)cc3C)CC2)ccc1Cl.N>>COc1cc(N2CCC(C(N)Cn3nc(C(F)(F)F)cc3C)CC2)ccc1Cl -US20110160208A1,3,COc1cc(F)c(Br)c(OC)c1.O=C(Cl)CC1CCCCC1>>COc1cc(OC)c(C(=O)CC2CCCCC2)c(F)c1Br -US20130244993A1,3,CCOC(=O)C1(c2cc(Br)ccn2)CC1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>CCOC(=O)C1(c2cc(-c3ccc([C@H](C)N4CC[C@](CC(C)(C)O)(c5ccccc5)OC4=O)cc3)ccn2)CC1 -US07608629B2,1,C[C@H]1C[C@@H](Oc2cccc(Cl)n2)CCN1C(=O)OC(C)(C)C.N=C(c1ccccc1)c1ccccc1>>C[C@H]1C[C@@H](Oc2cccc(N=C(c3ccccc3)c3ccccc3)n2)CCN1C(=O)OC(C)(C)C -US08927536B2,3,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(Br)cc4)CC3)n2CCS1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>Cn1nccc1-c1ccc(C2(c3nnc4n3CCSC(C)(CO[Si](C)(C)C(C)(C)C)C4)CC2)cc1 -US20150148332A1,7,Cc1cc(C)n2nc(C=Cc3nc(N(C)C4CC4)nn3C)nc2n1>>Cc1cc(C)n2nc(CCc3nc(N(C)C4CC4)nn3C)nc2n1 -US08354444B2,2,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.Nc1ccc2c(c1)C(=O)NC2=O>>CC(C)(C)CC1NC(C(=O)Nc2ccc3c(c2)C(=O)NC3=O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F -US06974831B2,6,COC(=O)COc1cc2c(c3c1c(C(=O)C(N)=O)c(C)n3Cc1ccccc1)CCC2>>Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3c(c2n1Cc1ccccc1)CCC3 -US20100168418A1,6,COc1ccc2ncc(=O)n(CCC3(O)CCC4(CC3)OCCO4)c2c1>>COc1ccc2ncc(=O)n(CCC3(O)CCC(=O)CC3)c2c1 -US20050107423A1,6,O=C(OCc1ccccc1)N1CC2CC(F)C(O)C2C1>>OC1C(F)CC2CNCC21 -US20140148443A1,2,CC(C)Oc1cc(Cl)c(S(N)(=O)=O)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl.CS(=O)(=O)CCCN1CCNCC1>>CC(C)Oc1cc(Cl)c(S(N)(=O)=O)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1 -US08580859B2,6,CSCC[C@H](NC(=O)CNC(=O)OC(C)(C)C)C(=O)NO>>CSCC[C@H](NC(=O)CN)C(=O)NO -US20130324719A1,1,C1COCCN1.O=[N+]([O-])c1ccc(F)c(F)c1>>O=[N+]([O-])c1ccc(N2CCOCC2)c(F)c1 -US04833150,4,CC(=O)CCC(C)=O.NCCO>>Cc1ccc(C)n1CCO -US06069141,1,CC(=O)NCC1CC(c2ccc(F)c(F)c2)=NO1.c1cc[nH]c1>>CC(=O)NCC1CC(c2ccc(-n3cccc3)c(F)c2)=NO1 -US20100041658A1,6,CCCc1ccc(Oc2cccc(N)n2)c(OC)c1>>CCCc1ccc(Oc2cccc(N)n2)c(O)c1 -US07592363B2,6,Fc1cc(F)c(Cn2nc3c(C(F)(F)F)cccc3c2-c2ccc(N3CCC4(CC3)OCCO4)cc2)c(F)c1>>O=C1CCN(c2ccc(-c3c4cccc(C(F)(F)F)c4nn3Cc3c(F)cc(F)cc3F)cc2)CC1 -US20080027050A1,6,COC(=O)c1ccc(CNC(=O)c2nc3ccc(OC)cc3c(=O)[nH]2)cc1>>COc1ccc2nc(C(=O)NCc3ccc(C(=O)O)cc3)[nH]c(=O)c2c1 -US20060194969A1,7,CN(C)c1nc2c([N+](=O)[O-])cc(Br)cc2n1C>>CN(C)c1nc2c(N)cc(Br)cc2n1C -US20040002497A1,7,CSc1ccc(-c2cc(C(=O)O)c(=O)n(CC(C)C)n2)cc1>>CSc1ccc(-c2cc(CO)c(=O)n(CC(C)C)n2)cc1 -US20040138462A1,6,CC(C)(C)OC(=O)N(CCc1ccc(S(=O)(=O)c2ccc(OC(F)F)cc2)cc1)C[C@H](O)c1cccc(Cl)c1>>O=S(=O)(c1ccc(CCNC[C@H](O)c2cccc(Cl)c2)cc1)c1ccc(OC(F)F)cc1 -US04328244,1,ClCc1ccc(Cl)cc1Cl.Nc1ccc(S(=O)(=O)O)cc1>>O=S(=O)(O)c1ccc(NCc2ccc(Cl)cc2Cl)cc1 -US08003649B2,1,FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12.O=Cc1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(CN2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1 -US04812565,1,CN1CCC(S)C1.O=C(O)c1cccnc1Cl>>CN1CCC(Sc2ncccc2C(=O)O)C1 -US07713994B2,7,COCOc1cc(C#N)ccc1-c1ccncc1>>COCOc1cc(CN)ccc1-c1ccncc1 -US05153214,2,COC(=O)CCCC(CCCN)CCc1cccnc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)CCCC(CCCNS(=O)(=O)c1ccc(Cl)cc1)CCc1cccnc1 -US20100278833A1,9,COC(=O)c1sc(-n2cnc3cnccc32)cc1OC(C)c1ccccc1Cl.N>>CC(Oc1cc(-n2cnc3cnccc32)sc1C(N)=O)c1ccccc1Cl -US06313160B1,2,CC(=O)OC(C)=O.NCC1=C(c2ccccc2)Oc2ccccc2O1>>CC(=O)NCC1=C(c2ccccc2)Oc2ccccc2O1 -US20110124633A1,1,CCCc1c(C=O)ccc2ccccc12.CN>>CCCc1c(CNC)ccc2ccccc12 -US06121272,2,COc1ccc(S(=O)(=O)Cl)cc1.O[C@H]1CCNC1>>COc1ccc(S(=O)(=O)N2CC[C@H](O)C2)cc1 -US08436023B2,1,CC(C)(C)[Si](C)(C)OC1CCC(=O)CC1.O=C(CNc1noc2ccc(C(F)(F)F)cc12)NC1CNC1>>CC(C)(C)[Si](C)(C)OC1CCC(N2CC(NC(=O)CNc3noc4ccc(C(F)(F)F)cc34)C2)CC1 -US04735940,8,O=C(c1cc(-c2ccccc2)c(=O)n2c1-c1sccc1CC2)N1CCC(O)CC1>>O=C1CCN(C(=O)c2cc(-c3ccccc3)c(=O)n3c2-c2sccc2CC3)CC1 -US20120264736A1,6,CC(C)(C)[Si](C)(C)OC1CCC2COc3c(F)ccc(F)c3C2(S(=O)(=O)c2ccc(Cl)cc2)CC1>>O=S(=O)(c1ccc(Cl)cc1)C12CCC(O)CCC1COc1c(F)ccc(F)c12 -US06051712,6,CC(C)(C)OC(=O)N1CCC(c2ncc(OCc3ccccc3)cn2)C(O)C1>>CC(C)(C)OC(=O)N1CCC(c2ncc(O)cn2)C(O)C1 -US04499277,9,Clc1cccc(C(Cl)(Cl)Cl)n1>>Clc1cccc(C(Cl)Cl)n1 -US20120295863A1,4,C#CCc1ccccc1.COc1ccc(CNc2ncnc3c2ncn3[C@@H]2O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H]2O)cc1>>COc1ccc(CNc2ncnc3c2ncn3[C@@H]2O[C@H](Cn3cc(Cc4ccccc4)nn3)[C@@H](O)[C@H]2O)cc1 -US20150045359A1,1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(N)cc2)C1.Clc1cccnc1Cl>>CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(Nc3ncccc3Cl)cc2)C1 -US07179823B1,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1cn(Cc2ccc(OCc3ccccc3)cc2)nc1-c1ccc(F)cc1>>CCOC(=O)/C=C/c1cn(Cc2ccc(OCc3ccccc3)cc2)nc1-c1ccc(F)cc1 -US05194442,3,O=C(Cl)CCCOc1ccccc1>>O=C1CCCOc2ccccc21 -US04497807,1,O=c1c(Cl)nsnc1Cl.Oc1ccc(Cl)cc1>>O=c1c(Cl)nsnc1Oc1ccc(Cl)cc1 -US07179823B1,1,CCOC(=O)Cc1c[nH]nc1-c1ccccc1.Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCl)cn1>>CCOC(=O)Cc1cn(Cc2ccc(OCCc3nc(-c4ccccc4)oc3C)nc2)nc1-c1ccccc1 -US20110053931A1,2,CC1(C(=O)O)CCN(c2ccc(F)cc2)C1=O.COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCOCC1>>COc1cc2c(Oc3ccc(NC(=O)C4(C)CCN(c5ccc(F)cc5)C4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 -US04014892,7,CC(=O)Nc1cccc(C(=O)CN2CCSC2=N)c1>>CC(=O)Nc1cccc(C(O)CN2CCSC2=N)c1 -US20040209857A1,7,C=CCN[C@H](C(=O)N1CCCC1)c1ccccc1>>C=CCN[C@H](CN1CCCC1)c1ccccc1 -US05329010,6,CCOC(=O)/C(=C/c1c(C)c(OC)c(OC)c(C)c1OC)CCCCCc1cccnc1>>COc1c(C)c(OC)c(OC)c(C)c1/C=C(\CCCCCc1cccnc1)C(=O)O -US20120245152A1,10,CC(C)(C)OC(=O)N1CCC(N2C(=O)C(C)(C)Cc3ncc(Cl)cc32)CC1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCC(N2C(=O)C(C)(C)C(Br)c3ncc(Cl)cc32)CC1 -US20150045378A1,6,COC(=O)c1cnc(OC)c(CCC#N)c1>>COC(=O)c1cnc(O)c(CCC#N)c1 -US20140206681A1,6,CC(C)(C)OC(=O)Nc1cc(C(F)F)ccn1>>Nc1cc(C(F)F)ccn1 -US20150284337A1,1,CC(C)N.CS(=O)(=O)c1ccc(-c2ccc3c(Cl)c(I)nnc3c2)cc1>>CC(C)Nc1c(I)nnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 -US20060069013A1,1,CCOC(=O)CBr.O=Cc1c[nH]c2ccccc12>>CCOC(=O)Cn1cc(C=O)c2ccccc21 -US20060166993A1,7,COc1cc(Oc2nc(-c3cccc([N+](=O)[O-])c3)nn3c(C)nc(C)c23)cc(OC)c1OC>>COc1cc(Oc2nc(-c3cccc(N)c3)nn3c(C)nc(C)c23)cc(OC)c1OC -US20040106635A1,2,CCOC(=O)CBr.Nc1ccccn1>>O=C(CBr)Nc1ccccn1 -US20100227845A1,1,CS(=O)(=O)C1CCNCC1.Clc1cc2nc(-c3cccnc3Cl)[nH]c2cc1Cl>>CS(=O)(=O)C1CCN(c2ncccc2-c2nc3cc(Cl)c(Cl)cc3[nH]2)CC1 -US05891909,1,Cc1cc(O)cc(OS(=O)(=O)c2cccc(C)c2)c1.OCCCO>>Cc1cc(OCCCO)cc(OS(=O)(=O)c2cccc(C)c2)c1 -US20080051418A1,7,CCOC(=O)CCc1cn(Cc2ccc(Cl)cc2Cl)nc1OCC>>CCOc1nn(Cc2ccc(Cl)cc2Cl)cc1CCCO -US06284785B1,2,Cc1ccc(S(=O)(=O)Cl)cc1.c1ccc(C2CCCN2)cc1>>Cc1ccc(S(=O)(=O)N2CCCC2c2ccccc2)cc1 -US20150175562A1,3,CC(C)(C)NS(=O)(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(F)(F)F.O=C(NC1CCOCC1)c1nc(CC2CCCCC2)c(Br)s1>>CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)NC3CCOCC3)nc2CC2CCCCC2)cc1C(F)(F)F -US07456218B2,5,COCCl.Cc1cc(O)cc(C)c1-c1cccc(C=O)c1>>COCOc1cc(C)c(-c2cccc(C=O)c2)c(C)c1 -US20020068753A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CNOC>>CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 -US20030083359A1,1,N[C@H]1CCCc2ccccc21.O=CC1CCCCC1>>c1ccc2c(c1)CCC[C@@H]2NCC1CCCCC1 -US05378848,7,O=[N+]([O-])c1c(Nc2ccon2)cnc2c1COCC2>>Nc1c(Nc2ccon2)cnc2c1COCC2 -US07348017B2,2,COc1ccc(S(=O)(=O)Cl)cc1.O=C(O)[C@@H]1CCCN1>>COc1ccc(S(=O)(=O)N2CCCC2C(=O)O)cc1 -US20080248419A1,6,C=Cc1ccc(OC(C)=O)cc1>>C=Cc1ccc(O)cc1 -US20090227555A2,2,CC(C)(C)OC(=O)N1CCN(c2ncc(C(=O)O)cc2Cl)CC1.CNOC>>CON(C)C(=O)c1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)c(Cl)c1 -US20150152108A1,1,COC(=O)C[C@H](N)C(=O)OC.O=[N+]([O-])c1ccc(Br)cc1F>>COC(=O)C[C@H](Nc1cc(Br)ccc1[N+](=O)[O-])C(=O)OC -US20050176733A1,1,CC(C)(C)OC(=O)NCCCBr.CCOC(=O)c1ccc(O)c([N+](=O)[O-])c1>>CCOC(=O)c1ccc(OCCCNC(=O)OC(C)(C)C)c([N+](=O)[O-])c1 -US20040167155A1,2,CC(=O)OC(C)=O.Nc1ccccc1-c1ccc(F)cc1>>CC(=O)Nc1ccccc1-c1ccc(F)cc1 -US06011033,1,ClCc1ncc2ccccc2n1.OCc1cccc(O)c1>>OCc1cccc(OCc2ncc3ccccc3n2)c1 -US07067657B2,9,BrC(Br)Br.CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(N)sc12>>CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(Br)sc12 -US20140343000A1,6,C=C(C)[C@@H]1CC[C@]2(NCCCN3CCCC3=O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)c(F)c6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCCCN3CCCC3=O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)c(F)c6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 -US05952321,1,CCCNC.CCC[C@@H](NC(=O)N1C(=O)C(CC)(CC)[C@@H]1Oc1ccc(C(O)COC)cc1)c1ccc(C)cc1>>CCC[C@@H](NC(=O)N1C(=O)C(CC)(CC)[C@@H]1Oc1ccc(C(COC)N(C)CCC)cc1)c1ccc(C)cc1 -US06432976B1,8,N#CCCn1c(CCCO)nc2ccccc21>>N#CCCn1c(CCC=O)nc2ccccc21 -US08357718B2,3,COC(=O)c1sc(-c2ccccc2)cc1N(C(=O)C1CCC(=O)CC1)C(C)C.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1CCC(C(=O)N(c2cc(-c3ccccc3)sc2C(=O)OC)C(C)C)CC1 -US20080103132A1,6,CC(C)(C)OC(=O)N1CCc2[nH]nc(-c3ccc(Cl)cc3)c2CC1>>Clc1ccc(-c2n[nH]c3c2CCNCC3)cc1 -US07572809B2,3,COc1ccc2c(Cl)nc(Nc3cc[nH]n3)cc2c1.OB(O)c1cc(F)cc(F)c1>>COc1ccc2c(-c3cc(F)cc(F)c3)nc(Nc3cc[nH]n3)cc2c1 -US07655641B2,3,CB(O)O.CCOC(=O)COc1ccc(CCCO)cc1I>>CCOC(=O)COc1ccc(CCCO)cc1C -US20100069357A1,2,CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CNCC3)cc1.COCC(=O)Cl>>CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CN(C(=O)COC)CC3)cc1 -US20110124665A1,1,Clc1ncnc2oc(-c3ccccc3)cc12.N[C@H]1CCC[C@H](O)C1>>O[C@H]1CCC[C@@H](Nc2ncnc3oc(-c4ccccc4)cc23)C1 -US04006179,6,CCOC(=O)CCCCC1CCCC1=O>>O=C(O)CCCCC1CCCC1=O -US05089654,6,CCCCCCc1ccc(C=CC(=O)c2ccc(OCC=C(C)C)cc2OCC(=O)OCC)cc1>>CCCCCCc1ccc(C=CC(=O)c2ccc(OCC=C(C)C)cc2OCC(=O)O)cc1 -US08455521B2,6,COC(C)(C)C[C@@H](CN(C)C(=O)OCC[Si](C)(C)C)NC(=O)OC(C)(C)C>>COC(C)(C)C[C@H](N)CN(C)C(=O)OCC[Si](C)(C)C -US06846953B1,2,CCC(=O)Cl.Nc1cccc2c1-c1ccccc1C2=O>>CCC(=O)Nc1cccc2c1-c1ccccc1C2=O -US20150166549A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cncc(Br)c1>>CC(C)(C)OC(=O)Nc1cncc(Br)c1 -US08263607B2,1,NCC1(O)CCCCC1.O=C(CCl)N1CCc2ccccc2[C@@H]1C1CCCCC1>>O=C(CNCC1(O)CCCCC1)N1CCc2ccccc2[C@@H]1C1CCCCC1 -US20140371278A1,1,COC(=O)c1cc(Br)c(F)c(F)c1Nc1ccccc1F.COc1ccc(CS)cc1>>COC(=O)c1cc(SCc2ccc(OC)cc2)c(F)c(F)c1Nc1ccccc1F -US20090270350A1,2,Cc1ccc(C(=O)O)cc1-n1c(C)cc(OCc2ccccc2CNC(=O)Nc2cc(C(C)(C)C)nn2-c2ccc(O)cc2)c(Cl)c1=O.NCCO>>Cc1ccc(C(=O)NCCO)cc1-n1c(C)cc(OCc2ccccc2CNC(=O)Nc2cc(C(C)(C)C)nn2-c2ccc(O)cc2)c(Cl)c1=O -US20110233466A1,3,CC1(C)OB(c2cc(F)c(C(F)(F)Oc3cc(F)c(C(F)(F)F)c(F)c3)c(F)c2)OC1(C)C.CCC[C@H]1CC[C@H](c2ccc(OS(=O)(=O)C(F)(F)F)c(F)c2)OC1>>CCCC1CCC(c2ccc(-c3cc(F)c(C(F)(F)Oc4cc(F)c(C(F)(F)F)c(F)c4)c(F)c3)c(F)c2)OC1 -US08173650B2,1,C1CC(C2COC2)CCN1.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C4COC4)CC3)n(C)c2n1 -US20020086999A1,3,CCN(CC)C(=O)n1cc(C=O)c2ccccc21.COc1cccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1>>CCN(CC)C(=O)n1cc(C=Cc2cccc(OC)c2)c2ccccc21 -US20090023729A1,6,CC(C)(C)OC(=O)N1CCc2cccc(CN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3ncc(N4CCOCC4)cn3)c21>>FC(F)(F)c1cc(CN(Cc2cccc3c2NCC3)c2ncc(N3CCOCC3)cn2)cc(C(F)(F)F)c1 -US06127354,2,CC(C)(C/C=C/C(=O)O)NC(=O)OC(C)(C)C.CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)CCCc1ccccc1>>CN(CCCc1ccccc1)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)/C=C/CC(C)(C)NC(=O)OC(C)(C)C -US20090099160A1,2,CNC.O=C(Cl)c1ccc(Br)cc1>>CN(C)C(=O)c1ccc(Br)cc1 -US20070179173A1,2,COc1ccc(CC2SC(=O)NC2=O)c2c1N(Cc1ccc(N)cc1)C(=O)CC2.CS(=O)(=O)Cl>>COc1ccc(CC2SC(=O)NC2=O)c2c1N(Cc1ccc(NS(C)(=O)=O)cc1)C(=O)CC2 -US04513004,2,COc1ccc(CO)cc1.O=C(Br)CBr>>COc1ccc(COC(=O)CBr)cc1 -US05877193,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1nc(-c2ccc(OCc3ccccc3)cc2)cs1>>Cc1ccc(S(=O)(=O)Nc2nc(-c3ccc(OCc4ccccc4)cc3)cs2)cc1 -US20060094707A1,8,CC(C)(C)C(=O)Nc1cc(Cl)ccc1CO>>CC(C)(C)C(=O)Nc1cc(Cl)ccc1C=O -US20070197621A1,4,CCC(=O)C(Cc1nccn1Cc1ccccc1)C(=O)CC.NN>>CCc1n[nH]c(CC)c1Cc1nccn1Cc1ccccc1 -US06610707B1,1,CC(C)(C)OC(=O)N1CCCC[C@H]1c1noc(COc2ccc(CO)cc2)n1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCCC[C@H]1c1noc(COc2ccc(CN3C(=O)c4ccccc4C3=O)cc2)n1 -US20130237525A1,1,CCI.O=Cc1cccc(F)c1O>>CCOc1c(F)cccc1C=O -US20100331322A1,6,CCO[C@H](C)COCc1ccc([C@H]2C[C@@H](CC(C)(C)C(=O)OC)N(S(=O)(=O)c3ccc(C)cc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1>>CCO[C@H](C)COCc1ccc([C@H]2C[C@@H](CC(C)(C)C(=O)O)N(S(=O)(=O)c3ccc(C)cc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1 -US20090326229A1,6,CCS(=O)(=O)c1cccc(-c2cc(C(=O)OC)c(C)c3[nH]c4ncc(C)cc4c23)c1>>CCS(=O)(=O)c1cccc(-c2cc(C(=O)O)c(C)c3[nH]c4ncc(C)cc4c23)c1 -US06174874B1,6,COC(=O)C(Cc1ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc1)(Cc1ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc1)C(=O)OCc1ccccc1>>COC(=O)C(Cc1ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc1)(Cc1ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc1)C(=O)O -US20100144710A1,2,CN(CC(=O)O)C(=O)OC(C)(C)C.N#Cc1cccnc1N1CCNCC1>>CN(CC(=O)N1CCN(c2ncccc2C#N)CC1)C(=O)OC(C)(C)C -US05399578,1,N#Cc1ccccc1-c1ccc(CBr)cc1.NC1(C(=O)OCc2ccccc2)CCCC1>>N#Cc1ccccc1-c1ccc(CNC2(C(=O)OCc3ccccc3)CCCC2)cc1 -US05868960,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOCCOCC(F)(F)C(F)(F)C(F)(F)F>>Cc1ccc(S(=O)(=O)OCCOCCOCC(F)(F)C(F)(F)C(F)(F)F)cc1 -US20150023913A1,9,CC(C)(C(=O)OCc1ccccc1)C1(O)CCCCO1>>CC(C)(C(=O)OCc1ccccc1)C1CCCCO1 -US20060194844A1,6,CCOC(=O)C1CCN(c2ncc(C(=O)Nc3nc(-c4cc(Cl)cs4)c(CN(C)CCOC)s3)cc2Cl)CC1>>COCCN(C)Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2)nc1-c1cc(Cl)cs1 -US20120184562A1,6,COC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(OC)cc3[nH]c2=O)c1>>COc1cc2[nH]c(=O)c(C(=O)Nc3cc(C(=O)O)ccc3Cl)cc2cn1 -US05523469,7,CC(c1cccc([N+](=O)[O-])c1)S(=O)(=O)[O-]>>CC(c1cccc(N)c1)S(=O)(=O)[O-] -US20140275093A1,9,COC(=O)c1ccc(C(C)=O)c(OC)c1.NO>>COC(=O)c1ccc(C(C)=NO)c(OC)c1 -US08183262B2,3,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.FC(F)(F)c1ccc(-c2cc(-c3cccc(Br)c3)nc(C(F)(F)F)c2)cc1>>Nc1ccc(-c2cccc(-c3cc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)c2)cn1 -US20070093521A1,1,BrCCCBr.CC(C)(C)OC(=O)N1CCC(Nc2nc3cc(O)ccc3o2)CC1>>CC(C)(C)OC(=O)N1CCC(Nc2nc3cc(OCCCBr)ccc3o2)CC1 -US05066653,3,CC(Cl)C(=O)Cl.Fc1ccccc1>>CC(Cl)C(=O)c1ccc(F)cc1 -US20080262048A1,7,O=C(c1cc(Cl)ccc1[N+](=O)[O-])C1CCCCC1>>Nc1ccc(Cl)cc1C(=O)C1CCCCC1 -US20070049618A1,1,COC(=O)c1cccc(I)c1C(=O)OC.COc1cccc(N)c1>>COC(=O)c1cccc(Nc2cccc(OC)c2)c1C(=O)OC -US20080306067A1,7,CC(=O)Nc1ccc(Br)c([N+](=O)[O-])c1>>CC(=O)Nc1ccc(Br)c(N)c1 -US04820705,2,COC(=O)CCC(=O)c1ccc2c(c1)CC(N)C2.COc1ccccc1S(=O)(=O)Br>>COC(=O)CCC(=O)c1ccc2c(c1)CC(NS(=O)(=O)c1ccccc1OC)C2 -US06143760,6,CCOC(=O)c1c[nH]c2ccc(OCC)nc2c1=O>>CCOc1ccc2[nH]cc(C(=O)O)c(=O)c2n1 -US20030073728A1,7,C=Cc1ccc(OCP(=O)(OCC)OCC)c([N+](=O)[O-])c1>>C=Cc1ccc(OCP(=O)(OCC)OCC)c(N)c1 -US20150011545A1,1,Cc1cc(N)n[nH]1.O=[N+]([O-])c1cc(F)c(F)nc1F>>Cc1cc(Nc2nc(F)c(F)cc2[N+](=O)[O-])n[nH]1 -US20120022056A1,6,CCOC(=O)c1ncn2c1COc1c(CCN3CCN(c4cccc5nc(C)ccc45)CC3)cccc1-2>>Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4c(C(=O)O)ncn4-5)CC3)cccc2n1 -US07678800B2,6,CC(C)(C)OC(=O)N1CCC(c2ccccc2Sc2c[nH]c3ccccc23)CC1>>c1ccc(C2CCNCC2)c(Sc2c[nH]c3ccccc23)c1 -US08013156B2,7,N#Cc1ccccc1N1CCN(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1>>NCc1ccccc1N1CCN(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 -US07049342B2,6,CCOC(=O)C(Cc1ccc(OC)c(NC(=O)Cc2ccc(C(F)(F)F)cc2)c1)OC>>COc1ccc(CC(OC)C(=O)O)cc1NC(=O)Cc1ccc(C(F)(F)F)cc1 -US09067898B1,3,C=CC(=O)OC.O=Cc1cc(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)ccc1Br>>COC(=O)/C=C/c1ccc(OCc2c(-c3ccc(Cl)cc3)nsc2C(F)(F)F)cc1C=O -US07247633B2,1,CN(C)c1ccc(CCO)cc1.Clc1cncc(Cl)n1>>CN(C)c1ccc(CCOc2cncc(Cl)n2)cc1 -US20030087874A1,6,COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@@H](NC(=O)OCc4ccccc4)[C@H](C)O)C(=O)OC(C)(C)C)[C@@H](O)[C@H]3O)c2=O)cc1>>COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@@H](N)[C@H](C)O)C(=O)OC(C)(C)C)[C@@H](O)[C@H]3O)c2=O)cc1 -US20050272778A1,1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(I)c(Br)c1)c1ncc(-c2ccccc2)[nH]1.C[Si](C)(C)CCOCCl>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(I)c(Br)c1)c1ncc(-c2ccccc2)n1COCC[Si](C)(C)C -US04920133,8,O=C(O)c1ccc(CCc2ccc(SCc3ccc4ccccc4n3)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>O=C(O)c1ccc(CCc2ccc(S(=O)Cc3ccc4ccccc4n3)cc2)cc1 -US20140187553A1,3,CC(C)(C)OC(=O)n1cc(I)c2cc(Br)ccc21.OB(O)c1cnc2ccccc2c1>>CC(C)(C)OC(=O)n1cc(-c2cnc3ccccc3c2)c2cc(Br)ccc21 -US20130030189A1,2,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.Cc1ccc(F)c(N=C=O)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c1 -US06569504B1,6,CCCCCC[C@H](C)Oc1ccc(-c2ccc(C(=O)OC)cc2)cc1[N+](=O)[O-]>>CCCCCC[C@H](C)Oc1ccc(-c2ccc(C(=O)O)cc2)cc1[N+](=O)[O-] -US20090030015A1,3,COC(=O)Cc1ccc(-c2ccccc2NC(=O)c2cncc(Br)c2)s1.COc1ccc(B(O)O)c(OC)c1>>COC(=O)Cc1ccc(-c2ccccc2NC(=O)c2cncc(-c3ccc(OC)cc3OC)c2)s1 -US20070191395A1,7,CCOC(=O)c1cc(C(C)(C)C)[nH]n1>>CC(C)(C)c1cc(CO)n[nH]1 -US20100249105A1,1,Fc1cncc(CBr)c1.NNc1ccc(F)cc1>>NN(Cc1cncc(F)c1)c1ccc(F)cc1 -US20110312945A1,1,CCOC(=O)CBr.Cc1[nH]c2c(c1Cc1ccc(S(=O)(=O)N3CCCC3)cc1)C(=O)CC(C)(C)C2>>CCOC(=O)Cn1c(C)c(Cc2ccc(S(=O)(=O)N3CCCC3)cc2)c2c1CC(C)(C)CC2=O -US08455479B2,6,CC(C)(C)OC(=O)NC(CC(=O)N1Cc2ccccc2-n2nnc(-c3ccc(F)cc3)c2C1)Cc1cc(F)c(F)cc1F>>N[C@@H](CC(=O)N1Cc2ccccc2-n2nnc(-c3ccc(F)cc3)c2C1)Cc1cc(F)c(F)cc1F -US20100137323A1,3,CCOC(=O)C[C@@H](/C=C/I)c1ccc(OC2CCCCO2)cc1.[Zn+]Cc1ccccc1>>CCOC(=O)C[C@@H](/C=C/Cc1ccccc1)c1ccc(OC2CCCCO2)cc1 -US20150210682A1,6,CCOc1ccc(Br)c(CC(=O)OC)c1>>CCOc1ccc(Br)c(CC(=O)O)c1 -US20110034507A1,6,COC(=O)c1cccc(N2CCc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3C2=O)c1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2c(c1)CCN(c1cccc(C(=O)O)c1)C2=O -US20100069381A1,2,COC(=O)c1ccc2ccn(-c3ccc(SC)cc3)c2c1.NN>>CSc1ccc(-n2ccc3ccc(C(=O)NN)cc32)cc1 -US06610692B1,6,CCOC(=O)Cn1c(C)cnc(Nc2cccnc2CC)c1=O>>CCc1ncccc1Nc1ncc(C)n(CC(=O)O)c1=O -US20050065128A1,7,C=C1[C@H](O[Si](C)(C)C(C)(C)C)CC(O)(C(=O)OC)C[C@H]1O[Si](C)(C)C(C)(C)C>>C=C1[C@H](O[Si](C)(C)C(C)(C)C)CC(O)(CO)C[C@H]1O[Si](C)(C)C(C)(C)C -US20120289522A1,1,Cc1noc(-c2ccc(Br)cc2)c1N.O=C1Cc2ccccc2C1>>Cc1noc(-c2ccc(Br)cc2)c1NC1Cc2ccccc2C1 -US20130281438A1,2,NC1CCCCC1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NC1CCCCC1 -US20140364433A1,3,CCCC[Sn](CCCC)(CCCC)c1ncccn1.Cc1ccc(I)c(C(=O)N2CCC[C@@H](C)[C@H]2CN2C(=O)c3ccccc3C2=O)c1>>Cc1ccc(-c2ncccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN2C(=O)c3ccccc3C2=O)c1 -US20060030609A1,1,FCCI.O=C1Nc2ccccc2C1=O>>O=C1C(=O)N(CCF)c2ccccc21 -US20070265272A1,3,CON(C)C(=O)c1ccc2ncccc2c1.C[Mg+]>>CC(=O)c1ccc2ncccc2c1 -US20140057899A1,9,C[Si](C)(C)CCOCn1cc(I)c2c(Cl)ncnc21.N>>C[Si](C)(C)CCOCn1cc(I)c2c(N)ncnc21 -US20100249095A1,6,CC(C)(C)OC(=O)N1CCC2(CCN(c3ccccn3)CC2)C1>>c1ccc(N2CCC3(CCNC3)CC2)nc1 -US20140135332A1,1,COc1ccc(-c2coc([C@@H](C)O)n2)cc1.NC(=O)c1c(F)ccc(O)c1F>>COc1ccc(-c2coc([C@H](C)Oc3ccc(F)c(C(N)=O)c3F)n2)cc1 -US20120283289A1,1,BrCc1ccccc1.CC(=O)c1ccc(O)c2[nH]c(=O)ccc12>>CC(=O)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12 -US06048885,10,CON=C(C#N)c1ccccc1C.O=C1CCC(=O)N1Br>>CON=C(C#N)c1ccccc1CBr -US05866589,1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1cccnc1Br>>CC(C)(C)OC(=O)N1CCN(c2ncccc2C=O)CC1 -US20090186900A1,7,COc1ccc(-c2ccccc2)cc1C#Cc1ccccc1>>COc1ccc(-c2ccccc2)cc1CCc1ccccc1 -US07919653B2,1,CC(C)(C)[Si](C)(C)Oc1cc(O)cc(O[Si](C)(C)C(C)(C)C)c1.OCCOCCOCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](C)(C)Oc1cc(OCCOCCOCCOCCOCCOC(c2ccccc2)(c2ccccc2)c2ccccc2)cc(O[Si](C)(C)C(C)(C)C)c1 -US20080167346A1,6,CC(C)N1CCC(NS(=O)(=O)C(C)CNC(=O)OCc2ccccc2)CC1>>CC(C)N1CCC(NS(=O)(=O)C(C)CN)CC1 -US20120202794A1,2,CC(C)C[C@H]1CN[C@@H](CC(C)C)C(=O)N1.O=C(O)[C@@H]1C[C@H]1c1ccccc1>>CC(C)C[C@H]1CN(C(=O)[C@@H]2C[C@H]2c2ccccc2)[C@@H](CC(C)C)C(=O)N1 -US04059587,1,C=[N+]=[N-].CCCOCC(O)CCC1N(CCCCCCC(=O)O)C(=O)CS1=O>>CCCOCC(O)CCC1N(CCCCCCC(=O)OC)C(=O)CS1=O -US20150175601A1,1,C=CC(=O)Nc1cccc(-c2cccc3cnc(Cl)nc23)c1.CC(=O)N1CC[C@H](Oc2ccc(N)cc2)C1>>C=CC(=O)Nc1cccc(-c2cccc3cnc(Nc4ccc(O[C@H]5CCN(C(C)=O)C5)cc4)nc23)c1 -US05057525,6,O=C(N[C@@H]1CCN(Cc2ccccc2)C[C@H]1O)c1ccccc1>>N[C@@H]1CCN(Cc2ccccc2)C[C@H]1O -US08178578B2,3,COc1cc(C=O)c(Br)c(OC)c1OC.O=Cc1cc([N+](=O)[O-])ccc1Cl>>COc1cc(C=O)c(-c2ccc([N+](=O)[O-])cc2C=O)c(OC)c1OC -US07351719B2,2,CN1CCN(Cc2ccc(N)cc2)CC1.O=C(O)/C=C/c1ccc(-c2ccc(Cl)cc2)cc1>>CN1CCN(Cc2ccc(NC(=O)/C=C/c3ccc(-c4ccc(Cl)cc4)cc3)cc2)CC1 -US20120214784A1,1,CCOC(=O)c1cn(-c2c(F)cccc2C=O)nc1C.CNC>>CCOC(=O)c1cn(-c2c(F)cccc2CN(C)C)nc1C -US05691349,3,CCCCOc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.O=CC1CN2CCC1CC2>>CCCCOc1ccc(/C=C\C2CN3CCC2CC3)cc1 -US20030191309A1,7,COC(=O)CCN(CCc1ccc(OC)cc1)S(=O)(=O)c1cccc([N+](=O)[O-])c1>>COC(=O)CCN(CCc1ccc(OC)cc1)S(=O)(=O)c1cccc(N)c1 -US20100120798A1,6,CC(C)(C)OC(=O)N1CCC(CN)(C(=O)Nc2ccccn2)CC1>>NCC1(C(=O)Nc2ccccn2)CCNCC1 -US20080287439A1,1,Cc1nc(C)c(-c2ccnc(Nc3cccc(CO)c3)n2)s1.ClCCN1CCOCC1>>Cc1nc(C)c(-c2ccnc(Nc3cccc(COCCN4CCOCC4)c3)n2)s1 -US20080318943A1,3,CN1Cc2nc3c(Br)cccc3c(N)c2C1=O.COc1ccc(B(O)O)c(OC)n1>>COc1ccc(-c2cccc3c(N)c4c(nc23)CN(C)C4=O)c(OC)n1 -US06890915B2,2,CC(C)c1nc2ccccc2n1Cc1ccc(N)cc1.O=C(O)CC1NC(=O)NC1=O>>CC(C)c1nc2ccccc2n1Cc1ccc(NC(=O)CC2NC(=O)NC2=O)cc1 -US05192781,7,CCCCCc1nc(N)sc1Cc1ccc([N+](=O)[O-])cc1>>CCCCCc1nc(N)sc1Cc1ccc(N)cc1 -US05814653,2,CN(C)C1CCc2[nH]c3ccc(N)cc3c2C1.O=S(=O)(Cl)c1ccc(I)cc1>>CN(C)C1CCc2[nH]c3ccc(NS(=O)(=O)c4ccc(I)cc4)cc3c2C1 -US06521643B1,3,Cc1cccnc1Br.O=[N+]([O-])c1cccc(B(O)O)c1>>Cc1cccnc1-c1cccc([N+](=O)[O-])c1 -US20110172442A1,6,CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)C=Cc1ccccc1F)C(=O)O>>NCCCC[C@H](NC(=O)C=Cc1ccccc1F)C(=O)O -US20040002497A1,6,COC(=O)c1cc(-c2ccc(F)c(C)c2)nn(CC(C)C)c1=O>>Cc1cc(-c2cc(C(=O)O)c(=O)n(CC(C)C)n2)ccc1F -US07514470B2,1,CC(C)(C)OC(=O)CBr.N#Cc1ccc(NCC2CC2)cc1C(F)(F)F>>CC(C)(C)OC(=O)CN(CC1CC1)c1ccc(C#N)c(C(F)(F)F)c1 -US20090324581A1,7,COC(=O)c1ccc(C(C)C)c(C(F)(F)F)c1>>CC(C)c1ccc(CO)cc1C(F)(F)F -US07803793B2,3,COc1ncc(Br)cc1CN(c1ccc(Oc2ccc(C)cc2)cc1)S(C)(=O)=O.OB(O)c1ccccc1>>COc1ncc(-c2ccccc2)cc1CN(c1ccc(Oc2ccc(C)cc2)cc1)S(C)(=O)=O -US07030141B2,2,CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(N)c(F)c1.CC(C)(C)OC(=O)N1CCCC1C(=O)O>>CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2CCCN2C(=O)OC(C)(C)C)c(F)c1 -US06384051B1,1,CNC.COc1cc2c(Nc3ccc(C)c(O)c3)c(C#N)cnc2cc1OCCCl>>COc1cc2c(Nc3ccc(C)c(O)c3)c(C#N)cnc2cc1OCCN(C)C -US06900224B2,3,C=C1CN(Cc2ccccc2)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1C.ICI>>C[C@H]1C(NC(=O)OC(C)(C)C)CN(Cc2ccccc2)CC12CC2 -US05281593,7,O=Cc1ccc2ccn(C(c3ccccc3)c3cccc(/C=C/c4ccc5ccccc5n4)c3)c2c1>>OCc1ccc2ccn(C(c3ccccc3)c3cccc(/C=C/c4ccc5ccccc5n4)c3)c2c1 -US05075445,9,CC1(C)OCC(CCn2cnc3c(N=[N+]=[N-])nc(N)nc32)CO1>>CC1(C)OCC(CCn2cnc3c(N)nc(N)nc32)CO1 -US05457104,1,C1CC2CNCC2N1.O=C(O)c1cn(C2CC2)c2c(Cl)c(F)ccc2c1=O>>O=C(O)c1cn(C2CC2)c2c(Cl)c(N3CC4CCNC4C3)ccc2c1=O -US04557753,1,Cn1ncc(C(=O)c2ccc(Cl)cc2Cl)c1O.O=[N+]([O-])c1ccc(CCl)cc1>>Cn1ncc(C(=O)c2ccc(Cl)cc2Cl)c1OCc1ccc([N+](=O)[O-])cc1 -US06218385B1,1,COCCl.N#Cc1c(N2CCc3ccccc3CC2)nc[nH]c1=O>>COCn1cnc(N2CCc3ccccc3CC2)c(C#N)c1=O -US07888352B2,1,CN1CCC(C=O)CC1.CNCc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CN1CCC(CN(C)Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1 -US08536165B2,7,COc1ncc([N+](=O)[O-])cc1-c1ccccc1>>COc1ncc(N)cc1-c1ccccc1 -US05292937,2,CCOC(=O)C(C)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>CCOC(=O)C(C)C(=O)Nc1cc(Cl)cc(Cl)c1 -US06211373B1,7,O=[N+]([O-])c1cccc(OCc2ccccc2)c1O>>Nc1cccc(OCc2ccccc2)c1O -US07196090B2,6,COC(=O)c1c(OC)c(F)c(NCc2ccccc2)c(F)c1OC>>COc1c(F)c(NCc2ccccc2)c(F)c(OC)c1C(=O)O -US20080255085A1,4,COc1ccc(-c2ccnc(N)c2N)cc1.O=C(O)c1ccc[nH]1>>COc1ccc(-c2ccnc3[nH]c(-c4ccc[nH]4)nc23)cc1 -US20060276496A1,3,CCOC(=O)C[N+](=O)[O-].COC(=O)c1ccc2c(c1)c(C=O)cn2C(=O)OCc1ccccc1>>CCOC(=O)C(=Cc1cn(C(=O)OCc2ccccc2)c2ccc(C(=O)OC)cc12)[N+](=O)[O-] -US06958145B2,3,CCCCCCCC(C)=O.O=CC(=O)O>>CCCCCCC(=CC(=O)O)C(C)=O -US20150210682A1,1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2CC.COCCCBr>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCOC)cc1CC2CC -US20090281127A1,6,O=C(Nc1cccnc1)N[C@@H]1CCN(c2nc(NCC(c3ccccc3)c3ccccc3)c3ncn([C@@H]4C[C@H](NC(=O)OCc5ccccc5)[C@@H](O)[C@H]4O)c3n2)C1>>N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CC[C@@H](NC(=O)Nc5cccnc5)C4)nc32)[C@H](O)[C@@H]1O -US07101905B2,3,CC1(c2cccc(Cl)c2)CN(Cc2ccccc2)CCC1=O.CCOC(=O)CC#N>>CCOC(=O)C(C#N)=C1CCN(Cc2ccccc2)CC1(C)c1cccc(Cl)c1 -US20050261333A1,7,O=[N+]([O-])c1ccc(-c2nc3cc(Br)cnc3[nH]2)cc1>>Nc1ccc(-c2nc3cc(Br)cnc3[nH]2)cc1 -US20110319429A1,6,CC(C)(C)OC(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)cc1>>O=C(O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 -US20150164876A1,6,COCCOCCOCCOCCOCCOCCOCCN(CCOC)CCN(C)C(=O)OCc1ccccc1>>CNCCN(CCOC)CCOCCOCCOCCOCCOCCOCCOC -US20090221712A1,3,CN(C)C=O.Clc1cc(OCc2ccccc2)cc(OCc2ccccc2)c1>>O=Cc1c(Cl)cc(OCc2ccccc2)cc1OCc1ccccc1 -US20100130558A1,2,NC1CC[C@H]2CN(Cc3ccccc3)C[C@@H]12.O=C(O)C(C1CCCCC1)C1CCCCC1>>O=C(N[C@H]1CC[C@H]2CN(Cc3ccccc3)C[C@H]21)C(C1CCCCC1)C1CCCCC1 -US20130172354A1,1,Fc1cccc(CNc2cccc(-c3cc(F)ncc3Cl)n2)c1.N[C@@H]1CC[C@H](CO)C1>>OC[C@H]1CC[C@@H](Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1 -US07935688B2,3,CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1.CCOC(=O)Cc1ccc(Cl)nc1>>CCOC(=O)Cc1ccc(-c2ccc(C(CC)(CC)c3ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c3)cc2C)nc1 -US20120289520A1,3,COC(=O)C(C)c1ccc(B2OC(C)(C)C(C)(C)O2)c(Cl)c1.Cc1nc(C)c(-c2ccc(OS(=O)(=O)C(F)(F)F)c(F)c2)nc1C(N)=O>>COC(=O)C(C)c1ccc(-c2ccc(-c3nc(C(N)=O)c(C)nc3C)cc2F)c(Cl)c1 -US05516788,1,CI.c1ccc2c(c1)C[C@@H]1c3ccccc3N[C@H]21>>CN1c2ccccc2[C@H]2Cc3ccccc3[C@H]21 -US04925863,3,CN(C)C=O.FC(F)(F)Oc1ccc(I)cc1>>O=Cc1ccc(OC(F)(F)F)cc1 -US20040116464A1,1,CNC[C@@H](O)c1ccccc1.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CO)sc21>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2s1)C[C@@H](O)c1ccccc1 -US20030162790A1,1,C1CNCCN1.Fc1cccnc1Cl>>Fc1cccnc1N1CCNCC1 -US20120129840A1,3,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl.COc1ccc(B(O)O)c(F)c1>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1ccc(OC)cc1F -US20090221555A1,1,CNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.COc1cc2c(cc1N)CCOC(=O)N2C>>CNC(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)N(C)C(=O)OCC3)ncc1Cl -US20120040985A1,2,COc1ccc(C(C)(C)C(=O)NN)cc1OC.Fc1ccc(N=C=S)cc1>>COc1ccc(C(C)(C)C(=O)NNC(=S)Nc2ccc(F)cc2)cc1OC -US20150197532A1,2,CNc1ncc(I)cc1N.O=C(O)c1ncccc1Cl>>CNc1ncc(I)cc1NC(=O)c1ncccc1Cl -US20060178384A1,1,COc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.Nc1ccc2[nH]ncc2c1>>COc1ccc2c(c1)CCn1c-2cc(Nc2ccc3[nH]ncc3c2)nc1=O -US04057573,2,CO.O=C(O)CC1CCc2cc(C(=O)c3ccccc3)c(O)cc21>>COC(=O)CC1CCc2cc(C(=O)c3ccccc3)c(O)cc21 -US08138189B2,9,COC(=O)C(C(=O)c1ccnc(C)c1)c1ccc(OC)cc1Cl>>COc1ccc(CC(=O)c2ccnc(C)c2)c(Cl)c1 -US20140275030A1,1,CC(C)N.Cc1noc(C)c1-c1cc(C=O)c2[nH]c(=O)n3c2c1OC[C@@H]3c1ccccn1>>Cc1noc(C)c1-c1cc(CNC(C)C)c2[nH]c(=O)n3c2c1OCC3c1ccccn1 -US08507484B2,6,CCc1nc2c(C)cc(C)nc2n1Cc1cnc(N(C(=O)OC(C)(C)C)c2ccccc2)nc1>>CCc1nc2c(C)cc(C)nc2n1Cc1cnc(Nc2ccccc2)nc1 -US20130338367A1,6,CCOC(=O)c1cn(-c2cccnc2)nc1C>>Cc1nn(-c2cccnc2)cc1C(=O)O -US20050032873A1,1,CC=O.COc1cccc2c(CCCNC3COc4c(F)ccc(C(N)=O)c4C3)coc12>>CCN(CCCc1coc2c(OC)cccc12)C1COc2c(F)ccc(C(N)=O)c2C1 -US20150119431A1,6,CC(C)(C)OC(=O)NN1C[C@H](COCc2ccccc2)OC1=O>>CC(C)(C)OC(=O)NN1C[C@H](CO)OC1=O -US04076821,3,Nc1ccccc1.O=C1CCN(C2CCC(c3ccc(F)cc3)(c3ccc(F)cc3)CC2)CC1.[C-]#N>>N#CC1(Nc2ccccc2)CCN(C2CCC(c3ccc(F)cc3)(c3ccc(F)cc3)CC2)CC1 -US20110124633A1,1,CCOC(=O)CN.Nc1ncc(Br)cc1CBr>>CCOC(=O)CNCc1cc(Br)cnc1N -US20150266881A1,1,N[C@@H]1C[C@H]1c1cccc(C(=O)NC2CCOCC2)c1.O=C1CCC1>>O=C(NC1CCOCC1)c1cccc([C@@H]2C[C@H]2NC2CCC2)c1 -US20150141406A1,2,CN.COc1nccc2c1c(-c1ccc(C(=O)O)cc1)nn2-c1c(F)cccc1F>>CNC(=O)c1ccc(-c2nn(-c3c(F)cccc3F)c3ccnc(OC)c23)cc1 -US20080076924A1,2,O=C=Nc1ccc(Cl)cc1.c1ccc(C2CNCCN2)cc1>>O=C(Nc1ccc(Cl)cc1)N1CCNCC1c1ccccc1 -US04226792,1,CI.O=Cc1ccc(O)cc1O>>COc1ccc(C=O)c(O)c1 -US05231188,3,CC(=O)NCC1OC(=O)N2c3ccc(Br)cc3CC12.OB(O)c1ccccc1>>CC(=O)NCC1OC(=O)N2c3ccc(-c4ccccc4)cc3CC12 -US20080194585A1,3,COc1ccc(CN)cc1.O=Cc1c(F)cccc1F.[C-]#N>>COc1ccc(CNC(C#N)c2c(F)cccc2F)cc1 -US07202363B2,6,CCOC(/C=C/c1cnc(N)c2c(-c3ccc(NC(=O)c4cc5ccccc5n4C)c(OC)c3)csc12)OCC>>COc1cc(-c2csc3c(/C=C/C=O)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C -US20050176796A1,2,CCOC(=O)c1nn(-c2ccc(OC)cc2)c2c1ccc1[nH]ncc12.NN>>COc1ccc(-n2nc(C(=O)NN)c3ccc4[nH]ncc4c32)cc1 -US07989446B2,6,CC(=O)Nc1ccc(-c2nc(SCc3cccc(CNC(=O)OC(C)(C)C)n3)nc(N)c2C#N)cc1>>CC(=O)Nc1ccc(-c2nc(SCc3cccc(CN)n3)nc(N)c2C#N)cc1 -US20080125436A1,2,CCOC(=O)c1ccn(COCC[Si](C)(C)C)c(=O)c1.NN>>C[Si](C)(C)CCOCn1ccc(C(=O)NN)cc1=O -US09045475B2,1,CN1CCC(F)(CO)CC1.NS(=O)(=O)c1ccc(F)c(Cl)c1>>CN1CCC(F)(COc2ccc(S(N)(=O)=O)cc2Cl)CC1 -US05696118,2,C1COCCN1.O=C(O)c1ccc([N+](=O)[O-])c(O)c1>>O=C(c1ccc([N+](=O)[O-])c(O)c1)N1CCOCC1 -US20070010511A1,1,COCCCN1C(=O)CCc2ccc(CCl)cc21.COc1ccccc1CCOCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1>>COCCCN1C(=O)CCc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCOCCc4ccccc4OC)cc3)cc21 -US04877899,2,CCCCCCSC(F)=CCO.CN(C)C(=O)Cl>>CCCCCCSC(F)=CCOC(=O)N(C)C -US20040254237A1,9,CC(C)(Br)C(=O)c1ccsc1.[N-]=[N+]=[N-]>>CC(C)(N=[N+]=[N-])C(=O)c1ccsc1 -US20040087789A1,3,C#Cc1ccccc1.Clc1ncncc1I>>Clc1ncncc1C#Cc1ccccc1 -US20130172339A1,2,Nc1cccc(C(=O)O)c1.O=S(=O)(Cl)c1cc2ccccc2s1>>O=C(O)c1cccc(NS(=O)(=O)c2cc3ccccc3s2)c1 -US20130225579A1,1,N#Cc1cnc2cc(OC3CCOC3)c([N+](=O)[O-])cc2c1Cl.Nc1ccc(OCc2ccccn2)c(Cl)c1>>N#Cc1cnc2cc(OC3CCOC3)c([N+](=O)[O-])cc2c1Nc1ccc(OCc2ccccn2)c(Cl)c1 -US07595397B2,6,CC(C)C1CN(C(=O)OC(C)(C)C)CCO1>>CC(C)C1CNCCO1 -US05183894,1,N#Cc1c(C(=O)c2ccccc2)n(O)c2ccccc12.Nc1ccccc1>>N#Cc1c(C(=Nc2ccccc2)c2ccccc2)n(O)c2ccccc12 -US20130028919A1,2,CC(C)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.C[C@@H](N)C(=O)O>>CC(C)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@H](C)C(=O)O -US20110172245A1,1,Cc1ccc(NC(=O)c2cccc(C3(C#N)CC3)c2)cc1O.O=[N+]([O-])c1ccc(F)cc1>>Cc1ccc(NC(=O)c2cccc(C3(C#N)CC3)c2)cc1Oc1ccc([N+](=O)[O-])cc1 -US05606089,3,CC(=O)Oc1c(C(C)(C)C)cc2oc(C=O)cc2c1C(C)(C)C.CCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCCC=Cc1cc2c(C(C)(C)C)c(OC(C)=O)c(C(C)(C)C)cc2o1 -US08318928B2,2,CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)O)cccc1OC(F)F.NCc1cccc(C(F)(F)F)c1>>CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)NCc2cccc(C(F)(F)F)c2)cccc1OC(F)F -US20150057286A1,1,Brc1cncc2cc[nH]c12.CI>>Cn1ccc2cncc(Br)c21 -US20070054955A1,1,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@@H](Br)SC[C@H]1OC(C)=O.Oc1cccnc1>>CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2cccnc2)SC[C@H]1OC(C)=O -US20080269219A1,1,CC(C)c1ncc[nH]1.Cc1ccccc1OCCCc1oc(Cl)nc1-c1ccc(Cl)cc1>>Cc1ccccc1OCCCc1oc(-n2ccnc2C(C)C)nc1-c1ccc(Cl)cc1 -US20090156594A1,2,COC(=O)Cc1c(F)cc2ncccc2c1F.NN>>NNC(=O)Cc1c(F)cc2ncccc2c1F -US20130018030A1,1,CS(=O)(=O)N1CC=C(c2cc3c(cn2)O[C@@H](C2CCNCC2)C3)CC1.FC(F)(F)c1cnc(Cl)cn1>>CS(=O)(=O)N1CC=C(c2cc3c(cn2)O[C@@H](C2CCN(c4cnc(C(F)(F)F)cn4)CC2)C3)CC1 -US20150274664A1,6,CC(C)(C)OC(=O)N1CCC([C@H]2C[C@@H]2COCc2ccc(S(C)(=O)=O)cn2)CC1>>CS(=O)(=O)c1ccc(COC[C@H]2C[C@@H]2C2CCNCC2)nc1 -US20110118245A1,7,CCOc1cc([N+](=O)[O-])c(C(=O)OC)cc1OC>>CCOc1cc(N)c(C(=O)OC)cc1OC -US07105671B2,7,CS(=O)(=O)c1ccc([C@@H](CC2CCCC2=O)C(=O)Nc2cnccn2)cc1Cl>>CS(=O)(=O)c1ccc([C@@H](CC2CCCC2O)C(=O)Nc2cnccn2)cc1Cl -US20130296312A1,1,CN1CCN(c2cccc(N)c2)CC1.Fc1ccc(CNc2cccn3nc(Cl)nc23)cc1>>CN1CCN(c2cccc(Nc3nc4c(NCc5ccc(F)cc5)cccn4n3)c2)CC1 -US08470871B2,6,CCOC(=O)c1ccc(-c2ccc(OCCCCNC(C)C)c(-c3ccc(N(CC)CC)c(C(C)(C)C)c3)c2)cc1>>CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCNC(C)C)cc1C(C)(C)C -US08327467B2,6,CC(C)(C)OC(=O)c1ccc(-n2ccc3ccccc32)cc1Nc1ccc(F)cc1>>O=C(O)c1ccc(-n2ccc3ccccc32)cc1Nc1ccc(F)cc1 -US06528528B2,1,COc1ccc(C(=O)Nc2ccccc2)cc1N.O=[N+]([O-])c1cccc(I)c1>>COc1ccc(C(=O)Nc2ccccc2)cc1Nc1cccc([N+](=O)[O-])c1 -US20090012055A1,7,Cc1ccc(COC2CCCCO2)cc1[N+](=O)[O-]>>Cc1ccc(COC2CCCCO2)cc1N -US20090286778A1,2,O=C(COc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2)N1CCNCC1.O=C(Cl)c1ccc(F)cc1F>>O=C(COc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2)N1CCN(C(=O)c2ccc(F)cc2F)CC1 -US08541457B2,2,COc1cccc(C(=O)Cl)c1.Cc1nc(N)sc1C(=O)NCc1ccccc1>>COc1cccc(C(=O)Nc2nc(C)c(C(=O)NCc3ccccc3)s2)c1 -US03962378,6,CCOP(=O)(CCOC(C)=O)OCC>>CCOP(=O)(CCO)OCC -US20140105921A1,2,CCCCCCCCS(=O)(=O)Cl.COC[C@H](NC(=O)c1cnc(C)s1)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@](C)(O)CO>>CCCCCCCCS(=O)(=O)OC[C@@](C)(O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](COC)NC(=O)[C@H](COC)NC(=O)c1cnc(C)s1 -US20050203087A1,2,CCCCS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1.CO>>CCCCS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)OC)c3Br)c2)CC1 -US20150283106A1,1,C=CC(O)CCc1c(C)c(OC)c(OC)c(OC)c1OC.C=CCBr>>C=CCOC(C=C)CCc1c(C)c(OC)c(OC)c(OC)c1OC -US20050261331A1,4,NNc1ccc(Br)cn1.O=C(Cc1ccccc1)c1ncco1>>Brc1cnc2[nH]c(-c3ncco3)c(-c3ccccc3)c2c1 -US06727245B2,1,CC(=O)Nc1cccc(N)c1.O=[N+]([O-])c1cccnc1Cl>>CC(=O)Nc1cccc(Nc2ncccc2[N+](=O)[O-])c1 -US20070167486A1,2,Cc1ccc(CCCO)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(CCCOS(=O)(=O)c2ccc(C)cc2)cc1 -US08440666B2,6,CCOC(=O)C(Cc1ccncc1)n1ncc(N[C@@H]2C[C@@H]3C[C@H]([C@H]2C)C3(C)C)c(Br)c1=O>>C[C@H]1[C@H](Nc2cnn(C(Cc3ccncc3)C(=O)O)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C -US08173650B2,1,CCc1nc2ccccc2[nH]1.Cn1c(CN2CCC(C)(CO)CC2)nc2c(N3CCOCC3)nc(Cl)nc21>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C)(CO)CC3)n(C)c2n1 -US08778950B2,2,CC(C)(N)CO.O=C(O)c1nn(-c2cnc(O)cn2)c2c1C[C@H]1C[C@@H]21>>CC(C)(CO)NC(=O)c1nn(-c2cnc(O)cn2)c2c1C[C@H]1C[C@@H]21 -US04677212,9,CC1Cc2cc(Br)cc(S(N)(=O)=O)c2OS1(=O)=O>>CC1Cc2cccc(S(N)(=O)=O)c2OS1(=O)=O -US04341756,4,CC1(C)OCC=CCO1.O=C(OO)c1cccc(Cl)c1>>CC1(C)OCC2OC2CO1 -US08952010B2,1,COc1ccc2ncc(=O)n(CCC=O)c2c1.N[C@@H]1CC(=O)N(c2ccc3c(c2)NC(=O)CO3)C1>>COc1ccc2ncc(=O)n(CCCN[C@@H]3CC(=O)N(c4ccc5c(c4)NC(=O)CO5)C3)c2c1 -US08664230B2,3,CC1(C)OB(c2cncc(NS(=O)(=O)c3ccc(F)cc3F)c2)OC1(C)C.Clc1ccc2ncnc(OC3CCOCC3)c2n1>>O=S(=O)(Nc1cncc(-c2ccc3ncnc(OC4CCOCC4)c3n2)c1)c1ccc(F)cc1F -US20050096337A1,2,CCCCc1nc(-c2ccc(C(F)(F)F)cc2)ncc1CC(=O)O.CCOC(=O)C(C)(C)Oc1cccc(NC)c1>>CCCCc1nc(-c2ccc(C(F)(F)F)cc2)ncc1CC(=O)N(C)c1cccc(OC(C)(C)C(=O)OCC)c1 -USRE036625,2,C=C(C)C(=O)Cl.COc1ccc(/C=C/C(=O)N2CCC(O)CC2)cc1>>C=C(C)C(=O)OC1CCN(C(=O)/C=C/c2ccc(OC)cc2)CC1 -US04536569,1,CC(=O)Nc1cccc(N)c1.CCCCCCCCBr>>CCCCCCCCNc1cccc(NC(C)=O)c1 -US20120101086A1,6,Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(C(=O)CNC(=O)OC(C)(C)C)C2>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(C(=O)CN)C2 -US20150094296A1,7,CC(C)(CO)n1cc(Nc2nccc(N3CC[C@@](C#N)(C4CC4)C3=O)n2)cn1>>CC(C)(CO)n1cc(Nc2nccc(N3CC[C@@](CN)(C4CC4)C3=O)n2)cn1 -US20040023974A1,1,BrCc1ccccc1.O=Cc1ccc([N+](=O)[O-])c(O)c1>>O=Cc1ccc([N+](=O)[O-])c(OCc2ccccc2)c1 -US06251911B1,4,N#Cc1ccc(C=O)cc1.[N-]=[N+]=[N-]>>O=Cc1ccc(-c2nnn[nH]2)cc1 -US20080125429A1,2,Cc1nc(-c2ccc(Oc3ccc(N)c(CN4CCCC4=O)c3)cn2)no1.O=C(O)c1ccccn1>>Cc1nc(-c2ccc(Oc3ccc(NC(=O)c4ccccn4)c(CN4CCCC4=O)c3)cn2)no1 -US20110212968A1,2,COc1ccc(CCNCC2CC2)cc1OC.O=C(O)c1ccncc1Br>>COc1ccc(CCN(CC2CC2)C(=O)c2ccncc2Br)cc1OC -US06340679B1,2,CC(C)(C)OC(=O)[C@H](Cc1ccc(OCCCC(=O)O)cc1)NS(=O)(=O)c1ccc(C(F)(F)F)cc1.NC1=NCCCN1>>CC(C)(C)OC(=O)[C@H](Cc1ccc(OCCCC(=O)NC2=NCCCN2)cc1)NS(=O)(=O)c1ccc(C(F)(F)F)cc1 -US07084156B2,1,C1CCNCC1.O=[N+]([O-])c1ccc2nc(Cl)ccc2c1>>O=[N+]([O-])c1ccc2nc(N3CCCCC3)ccc2c1 -US04870074,1,CC(O)CN.O=Cc1ccccc1Cl>>CC(O)CNCc1ccccc1Cl -US20120129840A1,3,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1Cl.OB(O)c1ccc2cc[nH]c2c1>>CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2cc[nH]c2c1 -US20120277237A1,2,CS(=O)(=O)Cl.OCCC#Cc1cccc(CF)n1>>CS(=O)(=O)OCCC#Cc1cccc(CF)n1 -US20120252818A1,2,C=CC(=O)Cl.COc1nc(N2CCN(CCCCNC(=O)OC(C)(C)C)CC2)nc(OC)c1Sc1nccc(N)n1>>C=CC(=O)Nc1ccnc(Sc2c(OC)nc(N3CCN(CCCCNC(=O)OC(C)(C)C)CC3)nc2OC)n1 -US08247429B2,2,Cc1cc2c3c(ccn2n1)CCC3CCN.O=C(Cl)C1CC1>>Cc1cc2c3c(ccn2n1)CCC3CCNC(=O)C1CC1 -US20060079548A1,2,CN1CCCC1CCN.Cc1oc2cc(Oc3ccnc4ccsc34)ccc2c1C(=O)Cl>>Cc1oc2cc(Oc3ccnc4ccsc34)ccc2c1C(=O)NCCC1CCCN1C -US07906532B2,2,CC(=O)Cl.CC(C)n1nc(C(=O)N[C@H]2C[C@@H](CN)N(C(=O)OC(C)(C)C)C2)c2ccccc21>>CC(=O)NC[C@@H]1C[C@H](NC(=O)c2nn(C(C)C)c3ccccc23)CN1C(=O)OC(C)(C)C -US04216160,9,O=C(Cl)C(Cl)c1ccccc1.[NH4+]>>NC(=O)C(Cl)c1ccccc1 -US07880014B2,2,C=CCC(C)(C)CCO.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>C=CCC(C)(C)CCOC(=O)c1ccc([N+](=O)[O-])cc1 -US20080181866A1,2,Nc1nc(-c2ccc(C(=O)NC3CC3)cc2)cs1.O=C(O)C1CS[C@H](c2cncs2)N1C(=O)OCc1ccccc1>>O=C(NC1CC1)c1ccc(-c2csc(NC(=O)C3CS[C@H](c4cncs4)N3C(=O)OCc3ccccc3)n2)cc1 -US08093264B2,6,COc1ccccc1NC(=O)CC(=O)Nc1ccc(Oc2ccnc3cc(-c4cncn4C)sc23)c(F)c1>>Cn1cncc1-c1cc2nccc(Oc3ccc(NC(=O)CC(=O)Nc4ccccc4O)cc3F)c2s1 -US06800651B2,7,CN(c1ccccc1Cl)S(=O)(=O)c1cccc([N+](=O)[O-])c1>>CN(c1ccccc1Cl)S(=O)(=O)c1cccc(N)c1 -US20080318929A1,1,CC(C)(C)OC(=O)N1CCC(CNc2nc(Cl)ncc2[N+](=O)[O-])CC1.Cc1c(Br)cccc1CN>>Cc1c(Br)cccc1CNc1ncc([N+](=O)[O-])c(NCC2CCN(C(=O)OC(C)(C)C)CC2)n1 -US07855218B2,1,Fc1ccccc1CBr.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCc2ccccc2F)cc1 -US06645989B2,7,Cn1c(C=O)nc(-c2ccccc2)c1-c1ccncc1>>Cn1c(CO)nc(-c2ccccc2)c1-c1ccncc1 -US06100399,1,CC(=O)C=O.CCOC(=O)N1CCC(N)CC1>>CCOC(=O)N1CCC(N=CC(C)=O)CC1 -US08063234B2,7,CCOC(=O)CC(c1ccc2sccc2c1)c1c[nH]c2c(CSC)cccc12>>CSCc1cccc2c(C(CCO)c3ccc4sccc4c3)c[nH]c12 -US06284785B1,2,Fc1ccc(C2CCCN2)cc1.O=S(=O)(Cl)c1ccc2ccccc2c1>>O=S(=O)(c1ccc2ccccc2c1)N1CCCC1c1ccc(F)cc1 -US20080139558A1,2,COc1cccc(C(=O)Cl)c1.O=c1cc(CNc2cccc(Cl)c2)c2cccc(F)c2[nH]1>>COc1cccc(C(=O)N(Cc2cc(=O)[nH]c3c(F)cccc23)c2cccc(Cl)c2)c1 -US05346913,1,C#CCBr.CC1(C)NC(=O)N(Cc2ccccc2)C1=O>>C#CCN1C(=O)N(Cc2ccccc2)C(=O)C1(C)C -US20140121198A1,2,CS(=O)(=O)Cl.O=[N+]([O-])c1cnc2ccsc2c1N[C@@H]1CC[C@@H](CO)CC1>>CS(=O)(=O)OC[C@@H]1CC[C@@H](Nc2c([N+](=O)[O-])cnc3ccsc23)CC1 -US06242644B1,1,CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(O)cc(CC)c1.OB(O)c1ccccc1>>CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(CC)cc(Oc2ccccc2)c1 -US20080255147A1,3,COc1ccccc1B(O)O.Clc1nsc(Cl)n1>>COc1ccccc1-c1nc(Cl)ns1 -US20120238588A1,3,Brc1cnc2[nH]ccc2c1.OB(O)c1ccccc1>>c1ccc(-c2cnc3[nH]ccc3c2)cc1 -US04105773,1,CC(=O)Nc1csc(Br)n1.CCO>>CCOc1nc(NC(C)=O)cs1 -US07425554B2,1,CCC1(CC)CC=C(c2ccc(OC)cc2N2CCNCC2)CC1.O=CC1CCOCC1>>CCC1(CC)CC=C(c2ccc(OC)cc2N2CCN(CC3CCOCC3)CC2)CC1 -US20060084657A1,7,CC(C)N1CCC(C(C(=O)N2CCNCC2)c2ccc(F)cc2)CC1>>CC(C)N1CCC(C(CN2CCNCC2)c2ccc(F)cc2)CC1 -US20150023913A1,2,CCOC(=O)C1(CO)CC=CCO1.O=C(Cl)c1ccccc1>>CCOC(=O)C1(COC(=O)c2ccccc2)CC=CCO1 -US20070129413A1,3,COC(OC)c1ccc([Mg+])cc1.Clc1ccccc1-c1nnn(C2CCCCO2)n1>>COC(OC)c1ccc(-c2ccccc2-c2nnn(C3CCCCO3)n2)cc1 -US20120184587A1,2,CCc1cc(C(=O)Cl)cc(C#N)c1OC.c1ccc2c(c1)NCS2>>CCc1cc(C(=O)N2CSc3ccccc32)cc(C#N)c1OC -US20080036373A1,1,Ic1ccccc1.Nc1cc[nH]n1>>Nc1ccn(-c2ccccc2)n1 -US20150094297A1,1,CC(O)c1csc(-c2ccccc2)n1.COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OC(C)c2csc(-c3ccccc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 -US20100087427A1,7,COCCC=Cc1cc(Br)ccc1OC>>COCCCCc1cc(Br)ccc1OC -US08404673B2,2,N[C@@H]1CCCC[C@@H]1N1CCCC1.O=C(O)c1ccc(C(F)(F)F)cc1C1CC1>>O=C(N[C@@H]1CCCC[C@@H]1N1CCCC1)c1ccc(C(F)(F)F)cc1C1CC1 -US20130261101A1,1,Cc1nn(C(C)c2cc(Cl)c(C#N)c3c2OCCN(C2CNC2)C3)c2ncnc(N)c12.OCCBr>>Cc1nn(C(C)c2cc(Cl)c(C#N)c3c2OCCN(C2CN(CCO)C2)C3)c2ncnc(N)c12 -US07943607B2,2,CNCCO.O=S(=O)(Cl)c1ccc(F)cc1F>>CN(CCO)S(=O)(=O)c1ccc(F)cc1F -US06251928B1,1,COc1c(C(C)(C)C)cc(CBr)cc1C(C)(C)C.O=Cc1ccc(O)cc1>>COc1c(C(C)(C)C)cc(COc2ccc(C=O)cc2)cc1C(C)(C)C -US07709519B2,7,CC(=O)CC(O)c1cccc(C(=O)C(C(=O)c2cccc(F)c2)=C2Nc3ccccc3N2)c1>>CC(O)CC(O)c1cccc(C(=O)C(C(=O)c2cccc(F)c2)=C2Nc3ccccc3N2)c1 -US20110009401A1,1,CC(C)(C)OC(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1C=O.NCc1ccccc1>>CC(C)(C)OC(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1CNCc1ccccc1 -US20070197512A1,2,CC(C)(Br)C(=O)Br.Nc1ccccc1O>>CC(C)(Br)C(=O)Nc1ccccc1O -US20100105661A1,1,COC(=O)c1ccc(Br)s1.O=C1CCCN1>>COC(=O)c1ccc(N2CCCC2=O)s1 -US20120107273A1,9,O=C(NCc1ccc(OC(F)(F)F)cc1)[C@H]1CN(c2nc3nc(C4CC4)nc(Cl)c3s2)CCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1>>O=C(NCc1ccc(OC(F)(F)F)cc1)[C@H]1CN(c2nc3nc(C4CC4)ncc3s2)CCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1 -US08815864B2,1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(O)ccc(F)c43)ccc21.OB(O)c1cccnc1>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5cccnc5)ccc(F)c43)ccc21 -US20020052322A1,2,COC(=O)C(N)Cc1cccc(O)c1.C[C@H](NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)O>>COC(=O)C(Cc1cccc(O)c1)NC(=O)[C@H](C)NC(=O)Cc1cccc([N+](=O)[O-])c1 -US08580968B2,1,CNC(=O)c1ccc(Cl)nc1.Oc1ccc2nc(N3CC[C@@H](N4CCCCC4)C3)sc2c1>>CNC(=O)c1ccc(Oc2ccc3nc(N4CC[C@@H](N5CCCCC5)C4)sc3c2)nc1 -US06825354B2,7,CCOC(=O)C=C1CCSCC1>>CCOC(=O)CC1CCSCC1 -US20130053341A1,1,CNc1nc(-c2cccnc2)nc2ccc(-c3cccc(OCCCl)c3)cc12.C[O-]>>CNc1nc(-c2cccnc2)nc2ccc(-c3cccc(OCCOC)c3)cc12 -US20100120784A1,9,COc1ccc(COc2cc(C(N)=O)on2)cc1>>COc1ccc(COc2cc(C#N)on2)cc1 -US07989634B2,2,CC(=O)Cl.CC(C)(C)OC(=O)NCCO>>CC(=O)OCCNC(=O)OC(C)(C)C -US06765022B2,1,CO.Oc1ccc(CCCCN[C@@H]2CC[C@@H](c3ccccc3)CC2)cc1>>CN(CCCCc1ccc(O)cc1)[C@@H]1CC[C@@H](c2ccccc2)CC1 -US20110224136A1,2,NC1CCN(c2ccc(NC(=O)c3oc(N4CCCCC4)nc3C(F)(F)F)cn2)CC1.O=C(O)c1ccccc1F>>O=C(NC1CCN(c2ccc(NC(=O)c3oc(N4CCCCC4)nc3C(F)(F)F)cn2)CC1)c1ccccc1F -US07071221B2,2,CCCCOC(=O)Cl.COC(=O)C(N)Cc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1>>CCCCOC(=O)NC(Cc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1)C(=O)OC -US07547698B2,4,CCCCCC(=O)O.Nc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1N>>CCCCCc1nc2cc(N3CCN(C(=O)c4ccccc4C(F)(F)F)CC3)ccc2[nH]1 -US06992103B2,6,C[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCCC(C)(C)C>>C[C@H](C[C@H](O)[C@@H](N)Cc1ccccc1)C(=O)NCCC(C)(C)C -US20040162287A1,1,CN(C)C1(c2ccccc2)CCC(=O)CC1.Nc1ccc2c(c1)CCC2>>CN(C)C1(c2ccccc2)CCC(Nc2ccc3c(c2)CCC3)CC1 -US07119102B2,3,NC(=O)c1sc2nc(N3CCC(NCC(O)c4ccc(Br)cn4)CC3)cc(C(F)(F)F)c2c1N.O=C1Cc2ccc(Br)cc2N1>>NC(=O)c1sc2nc(N3CCC(NCC(O)c4ccc(-c5ccc6c(c5)NC(=O)C6)cn4)CC3)cc(C(F)(F)F)c2c1N -US20140309227A1,3,C=C(C)B1OC(C)(C)C(C)(C)O1.COC(=O)c1cc(-c2ccc(OC)cc2F)c2ccc(Cl)cc2n1>>C=C(C)c1ccc2c(-c3ccc(OC)cc3F)cc(C(=O)OC)nc2c1 -US20110190269A1,1,COc1cc(Br)ccc1-n1cnc(C)c1.Nc1nc2cccc(C(F)(F)F)n2n1>>COc1cc(Nc2nc3cccc(C(F)(F)F)n3n2)ccc1-n1cnc(C)c1 -US20070149508A1,3,C=O.COc1ccc(F)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1>>C=Cc1cc(OC)ccc1F -US20120226037A1,1,BrCc1ccccc1.Nc1nc2cc[nH]c2c(=O)[nH]1>>Nc1nc2ccn(Cc3ccccc3)c2c(=O)[nH]1 -US07144899B2,3,Clc1cnccn1.O=Cc1ccccc1B(O)O>>O=Cc1ccccc1-c1cnccn1 -US20090105124A1,7,COC(=O)c1c([N+](=O)[O-])cnn1C>>COC(=O)c1c(N)cnn1C -US08410123B2,1,CCOC(=O)[C@H](C)O.Fc1cccc(CSc2nc(Cl)cc(Cl)n2)c1F>>CCOC(=O)[C@H](C)Oc1cc(Cl)nc(SCc2cccc(F)c2F)n1 -US20100099695A1,7,O=C(O)c1cc(Br)cc(OC(F)(F)F)c1>>OCc1cc(Br)cc(OC(F)(F)F)c1 -US20130096084A1,6,CC(C)(C)OC(=O)N[C@H]1CCCN(Cc2ccccc2)C1>>N[C@H]1CCCN(Cc2ccccc2)C1 -US06933311B2,2,Cc1cc2c(CC(=O)O)cccc2cn1.NCc1ccc(C(F)(F)F)c(F)c1>>Cc1cc2c(CC(=O)NCc3ccc(C(F)(F)F)c(F)c3)cccc2cn1 -US06642379B1,2,CC(C)(C)C1=CN(c2c(Cl)cccc2C(=O)Cl)NO1.Cc1cc(OC(F)(F)F)ccc1N>>Cc1cc(OC(F)(F)F)ccc1NC(=O)c1cccc(Cl)c1N1C=C(C(C)(C)C)ON1 -US20090181934A1,2,CC(=O)OCC(=O)Cl.NC1CC(n2cnc3c(N[C@H](CO)Cc4ccccc4)nc(Cl)nc32)C(O)C1O>>CC(=O)OCC(=O)N[C@H]1C[C@@H](n2cnc3c(N[C@H](CO)Cc4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O -US20110212918A1,9,[N-]=[N+]=NCc1cc(O)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2>>NCc1cc(O)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2 -US20130252944A1,7,COc1ccc(Cn2cc(-c3nc(NC(=O)OC(C)(C)C)sc3C=O)c(C(C)O)n2)cc1>>COc1ccc(Cn2cc(-c3nc(NC(=O)OC(C)(C)C)sc3CO)c(C(C)O)n2)cc1 -US20060178510A1,3,CON(C)C(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCO1.Fc1cc(OCc2ccccc2)c(F)cc1Br>>CC(C)(C)OC(=O)N1CCO[C@H](C(=O)c2cc(F)c(OCc3ccccc3)cc2F)C1 -US08410100B2,2,CC(C)(C)OC(=O)Nc1cc(C(=O)O)cc(S(C)(=O)=O)c1.CNOC>>CON(C)C(=O)c1cc(NC(=O)OC(C)(C)C)cc(S(C)(=O)=O)c1 -US20060199817A1,2,CC(C)NC(C)C.Cc1ccccc1-c1ccc(C(=O)O)cc1>>Cc1ccccc1-c1ccc(C(=O)N(C(C)C)C(C)C)cc1 -US20050203087A1,1,CC(C)CN.CCOC(=O)COc1c(C(=O)OC)sc(-c2ccsc2C=O)c1Br>>CCOC(=O)COc1c(C(=O)OC)sc(-c2ccsc2CNCC(C)C)c1Br -US05424295,2,CC(=O)Cl.COc1nc(N)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O>>COc1nc(N)nc2c1ncn2[C@@H]1O[C@H](COC(C)=O)[C@@H](O)[C@@H]1O -US04725688,1,CCC(C)C(=O)O.CCCCCCCCCCCOc1cnc(-c2ccc(O)cc2)nc1>>CCCCCCCCCCCOc1cnc(-c2ccc(OC(=O)[C@@H](C)CC)cc2)nc1 -US20070225271A1,2,CC(C)(C)OC(=O)N1CCC(Nc2ncc(O)cn2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(Nc2ncc(OS(C)(=O)=O)cn2)CC1 -US20110263607A1,7,CCOC(=O)C(C)(C)C#N>>CCOC(=O)C(C)(C)CN -US20100056516A1,2,CCOC(=O)c1c(O)c2cccnc2n(O)c1=O.CNC>>CN(C)C(=O)c1c(O)c2cccnc2n(O)c1=O -US20040186091A1,1,C=O.c1ccc(N2CCC(c3nnc4n3-c3ccccc3CNC4)CC2)nc1>>CN1Cc2ccccc2-n2c(nnc2C2CCN(c3ccccn3)CC2)C1 -US20030095958A1,6,CC(C)(C)OC(=O)N1CCN(c2c(COc3ccccc3C(F)(F)F)cc(Br)cc2NC(=O)c2nccc3ccccc23)CC1>>O=C(Nc1cc(Br)cc(COc2ccccc2C(F)(F)F)c1N1CCNCC1)c1nccc2ccccc12 -US20070105820A1,3,O=C1C(=O)N(Cc2ccc(Cl)cc2)c2ccccc21.[Mg+]c1ccc2c(c1)OCCO2>>O=C1N(Cc2ccc(Cl)cc2)c2ccccc2C1(O)c1ccc2c(c1)OCCO2 -US20080260749A1,2,CC(C)(C)OC(=O)N1CCc2c(sc(N)c2C#N)C1.COc1ccccc1CCC(=O)O>>COc1ccccc1CCC(=O)Nc1sc2c(c1C#N)CCN(C(=O)OC(C)(C)C)C2 -US08124602B2,10,C=C[C@H]1CC[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C.O>>CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)CC[C@@H]1CCO -US06444704B1,6,CCOC(=O)C(C)(Cc1ccc(OCCN2CCCCC2)cc1)S(=O)(=O)c1ccc(Br)cc1>>CC(Cc1ccc(OCCN2CCCCC2)cc1)(C(=O)O)S(=O)(=O)c1ccc(Br)cc1 -US08877780B2,2,CC(C)(C)c1ccc(C(=O)Cl)cc1.NCc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O>>CC(C)(C)c1ccc(C(=O)NCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1 -US20060160864A1,3,CC(C)CN(C)c1ccc(Br)cc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1cc(Br)ccc1N(C)CC(C)C -US20100249396A1,6,CC(C)(C)OC(=O)N1CCCn2cc(CCOc3ccc4c(c3)CN(CC(F)(F)F)C(=O)[C@H](CC(=O)OCCN3CCOCC3)C4)nc21>>O=C(C[C@@H]1Cc2ccc(OCCc3cn4c(n3)NCCC4)cc2CN(CC(F)(F)F)C1=O)OCCN1CCOCC1 -US20120289474A1,6,CCc1nc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)co1>>CCc1nc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)co1 -US07528262B2,1,COCCc1cc2ccccc2n1-c1ccc(O)cc1.ClCCCN1CCCC1>>COCCc1cc2ccccc2n1-c1ccc(OCCCN2CCCC2)cc1 -US05730953,2,C[Si](C)(C)OCCNCCO[Si](C)(C)C.O=S(=O)(Cl)c1ccccc1>>C[Si](C)(C)OCCN(CCO[Si](C)(C)C)S(=O)(=O)c1ccccc1 -US20140288045A1,3,COc1cc(Cl)c(I)cc1N.OB(O)C1CC1>>COc1cc(Cl)c(C2CC2)cc1N -US20060116363A1,10,COC(=O)c1cccc(C)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cccc(CBr)c1 -US20070219210A1,6,CCOC(=O)c1cc(-c2ccc(C)cn2)n(-c2cccnc2)n1>>Cc1ccc(-c2cc(C(=O)O)nn2-c2cccnc2)nc1 -US05635510,2,COc1cc(C(=O)Cl)cc(OC)c1OC.OCCC1(c2ccc(Cl)c(Cl)c2)CCNC1>>COc1cc(C(=O)N2CCC(CCO)(c3ccc(Cl)c(Cl)c3)C2)cc(OC)c1OC -US05753679,2,O=C(Cl)c1ccc(Br)cc1.OC1CCN(Cc2ccccc2)CC1>>O=C(OC1CCN(Cc2ccccc2)CC1)c1ccc(Br)cc1 -US05891871,7,O=C1Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2Cl)=NN1)OCO3>>Nc1ccc(C2=NNC(=O)Cc3cc4c(cc32)OCO4)c(Cl)c1 -US04739066,6,CCOC(=O)C(O)CCCCC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(O)C(O)CCCCC1CCN(C(=O)OCc2ccccc2)CC1 -US20130217664A1,7,CCc1cc(N2CCCC2=O)ncc1[N+](=O)[O-]>>CCc1cc(N2CCCC2=O)ncc1N -US05811433,1,C1CN[C@@H]2CNC[C@@H]2C1.O=C(O)c1cn(C2CC2)c2c(Cl)c(Cl)ncc2c1=O>>O=C(O)c1cn(C2CC2)c2c(Cl)c(N3C[C@H]4NCCC[C@H]4C3)ncc2c1=O -US20100204207A1,1,Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2N.O=Cc1cc(F)cc(C(F)(F)F)c1>>Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2NCc1cc(F)cc(C(F)(F)F)c1 -US20150094296A1,6,CC(C)(C)OC(=O)Nc1cnn(C(C)(C)CS(C)(=O)=O)c1>>CC(C)(CS(C)(=O)=O)n1cc(N)cn1 -US05326902,6,CCOC(OCC)c1ccc(C(O)C#Cc2ccccc2)cc1>>O=Cc1ccc(C(O)C#Cc2ccccc2)cc1 -US08691848B2,1,CC(C)C(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)Cl.CCOC(=O)C1NN=C(C(C)(C)C)S1>>CCOC(=O)C1SC(C(C)(C)C)=NN1C(=O)C(NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccccc4C(F)(F)F)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccccc4C(F)(F)F)NC(=O)c4c[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US06071927,1,CI.COC(=O)Cc1ccc(O)c(Br)c1>>COC(=O)Cc1ccc(OC)c(Br)c1 -US05045541,1,CC(=O)COc1ccc(N2N=C3c4ccccc4SCC3CC2=O)cc1.CNC>>CC(COc1ccc(N2N=C3c4ccccc4SCC3CC2=O)cc1)N(C)C -US20150225354A1,2,CC(C)(C)OC(=O)CC1(CC(=O)OC(C)(C)C)CC(c2cc(O)ccc2CCC(=O)O)=NO1.O=S1(=O)CCNCC1>>CC(C)(C)OC(=O)CC1(CC(=O)OC(C)(C)C)CC(c2cc(O)ccc2CCC(=O)N2CCS(=O)(=O)CC2)=NO1 -US07081453B2,1,CS(=O)(=O)OC[C@@H]1COc2cccnc2O1.NCCCN1CCC(=O)NC1=O>>O=C1CCN(CCCNC[C@H]2COc3cccnc3O2)C(=O)N1 -US05644053,7,C[C@@]1(/C=C/C=O)S[C@@H]2CC(=O)N2[C@H]1C(=O)OC(c1ccccc1)c1ccccc1>>C[C@@]1(/C=C/CO)S[C@@H]2CC(=O)N2[C@H]1C(=O)OC(c1ccccc1)c1ccccc1 -US20150105373A1,3,CC[Mg+].CON(C)C(=O)C(NC(=O)OC(C)(C)C)c1ccc(OC(F)(F)F)cc1>>CCC(=O)C(NC(=O)OC(C)(C)C)c1ccc(OC(F)(F)F)cc1 -US05932571,1,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3[nH]2)CC1.COCCCl>>COCCn1c(N2CCCN(C(=O)OC(C)(C)C)CC2)nc2ccccc21 -US06358971B1,3,O=C(Cl)c1ccc(Cl)nc1.c1ccccc1>>O=C(c1ccccc1)c1ccc(Cl)nc1 -US20070066586A1,4,BrCCCCBr.COC(=O)Cc1ccc(N)cc1>>COC(=O)Cc1ccc(N2CCCC2)cc1 -US20110046186A1,9,Clc1cnc(Cl)c(Cl)c1.NN>>NNc1ncc(Cl)cc1Cl -US04694017,2,NC(CC1C(=O)Nc2ccccc21)C(=O)O.O=C(O)c1ccc(Cl)cc1>>O=C(NC(CC1C(=O)Nc2ccccc21)C(=O)O)c1ccc(Cl)cc1 -US08377923B2,2,CN.O=C(O)c1ccc(F)cc1C(F)(F)F>>CNC(=O)c1ccc(F)cc1C(F)(F)F -US05646140,2,COc1ccc(C(=O)Cl)cc1.Nc1ccccc1Nc1ccccc1>>COc1ccc(C(=O)Nc2ccccc2Nc2ccccc2)cc1 -US20120149707A1,3,CC[Mg+].CO/C=C(/C(=O)OC)c1ccccc1COc1cc(C)c(C=O)cc1C>>CCC(O)c1cc(C)c(OCc2ccccc2/C(=C\OC)C(=O)OC)cc1C -US07560463B2,6,CC(C)(C)OC(=O)N(CCc1ccccc1)Cc1ccc(Oc2cnc(C(N)=O)cn2)cc1>>NC(=O)c1cnc(Oc2ccc(CNCCc3ccccc3)cc2)cn1 -US04271173,6,CN1CCC2(CC1)S[C@@H]1C(NC(=O)Cc3ccccc3)C(=O)N1C2C(=O)OCc1ccccc1>>CN1CCC2(CC1)S[C@@H]1C(NC(=O)Cc3ccccc3)C(=O)N1C2C(=O)O -US05371296,7,C=CCOc1ccc(C(=O)CC(=O)C(C)(C)C)cc1OC>>CCCOc1ccc(C(=O)CC(=O)C(C)(C)C)cc1OC -US07217723B2,2,CNCCc1ccc(F)cc1.O=S(=O)(Cl)c1cc(Cl)sc1Cl>>CN(CCc1ccc(F)cc1)S(=O)(=O)c1cc(Cl)sc1Cl -US20100216788A1,1,Cc1cc([N+](=O)[O-])ccc1F.NC(=O)C1(c2cccc(O)c2)CC1>>Cc1cc([N+](=O)[O-])ccc1Oc1cccc(C2(C(N)=O)CC2)c1 -US20080234262A1,1,C[C@@H]1COCCN1.Oc1cccc(-c2nc(Br)c3cnn(-c4ccccc4)c3n2)c1>>C[C@@H]1COCCN1c1nc(-c2cccc(O)c2)nc2c1cnn2-c1ccccc1 -US06888032B2,9,Brc1ccc2[nH]ccc2c1.[C-]#N>>N#Cc1ccc2[nH]ccc2c1 -US08604021B2,1,COc1c(C)cc(F)cc1C(C)=O.N>>COc1c(C)cc(F)cc1C(C)N -US20090253687A1,3,Cc1cc(B(O)O)ccc1F.Cc1nn(C)c(-c2ccc3c(c2)NC(=O)CO3)c1Br>>Cc1cc(-c2c(C)nn(C)c2-c2ccc3c(c2)NC(=O)CO3)ccc1F -US20130210809A1,6,COc1ccc(Cn2cc(-c3nc(Nc4nsc(C)n4)sc3C#N)cn2)cc1>>Cc1nc(Nc2nc(-c3cn[nH]c3)c(C#N)s2)ns1 -US20140140956A1,3,COc1ccc(C=O)nc1Br.CS(=O)c1ccc(B(O)O)cc1>>COc1ccc(C=O)nc1-c1ccc(S(C)=O)cc1 -US07608629B2,1,CN1CCC(O)CC1.Fc1cc(F)cc(Br)c1>>CN1CCC(Oc2cc(F)cc(Br)c2)CC1 -US20070197604A1,1,Cc1oc(-c2ccc(Br)cc2)nc1CCOS(C)(=O)=O.O[C@H]1CCNC1>>Cc1oc(-c2ccc(Br)cc2)nc1CCN1CC[C@H](O)C1 -US08293721B2,7,CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4(C)CN(c5ccc([N+](=O)[O-])cn5)C(=O)O4)cc3)oc12>>CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4(C)CN(c5ccc(N)cn5)C(=O)O4)cc3)oc12 -US04500518,6,CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C -US06399629B1,2,CC(C)(C)OC(=O)N1C[C@H](Oc2cccc(-c3ccccc3)c2)C[C@H]1C(=O)O.CC(C)(C)OC(=O)NCCN>>CC(C)(C)OC(=O)NCCNC(=O)[C@@H]1C[C@@H](Oc2cccc(-c3ccccc3)c2)CN1C(=O)OC(C)(C)C -US04390724,6,COC(=O)CC(C(OC)OC)C(C)(C)S(=O)(=O)c1ccc(C)cc1>>COC(OC)C(CC(=O)O)C(C)(C)S(=O)(=O)c1ccc(C)cc1 -US04089853,7,c1ccc2[nH]ccc2c1>>c1ccc2c(c1)CCN2 -US04556667,1,Nc1cccnc1Nc1ccccc1C(=O)c1ccc(F)cc1>>Fc1ccc(C2=Nc3cccnc3Nc3ccccc32)cc1 -US06420363B1,3,CC(=O)c1ccc2c(c1)CCCN2C(C)C.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C(\C)c1ccc2c(c1)CCCN2C(C)C -US20060116386A1,8,O=C1O[C@@H](Cn2cc(CO)nn2)CN1c1ccc(I)c(F)c1>>O=Cc1cn(C[C@H]2CN(c3ccc(I)c(F)c3)C(=O)O2)nn1 -US20100080771A1,2,C=CCCOC(=O)N[C@H](C(=O)O)C(C)(C)C.C=Cc1cc([C@@]2(OC)CN[C@H](C(=O)OC)C2)ccc1-c1ccccc1>>C=CCCOC(=O)N[C@H](C(=O)N1C[C@](OC)(c2ccc(-c3ccccc3)c(C=C)c2)C[C@H]1C(=O)OC)C(C)(C)C -US05646171,1,CC(C)(C)C(=O)OCCl.CCCc1nc(C(C)(C)O)c(C(=O)O)[nH]1>>CCCc1nc(C(C)(C)O)c(C(=O)OCOC(=O)C(C)(C)C)[nH]1 -US07998988B2,3,CCOC(=O)c1ccc(Br)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 -US07661577B2,4,CC(Br)C(=O)c1ccc(Cl)c(Cl)c1.N=C(N)c1ccccc1>>Cc1[nH]c(-c2ccccc2)nc1-c1ccc(Cl)c(Cl)c1 -US08338605B2,1,COc1ccc(Sc2ccc(C)cc2N)cc1.Cc1ccc2c(Cl)ccnc2n1>>COc1ccc(Sc2ccc(C)cc2Nc2ccnc3nc(C)ccc23)cc1 -US20150133425A1,2,COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)O)C3.C[C@@H]1CC[C@@H](C)N1>>COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)N1[C@H](C)CC[C@H]1C)C3 -US20060241120A1,1,CC(C)N1CNC(=O)C12CCNCC2.Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(Cl)ncnc32)cc1>>CC(C)N1CNC(=O)C12CCN(c1ncnc3c1nc(-c1ccccc1Cl)n3-c1ccc(Cl)cc1)CC2 -US20090215829A1,1,ClCCOc1ccccc1Br.NCc1ccccn1>>Brc1ccccc1OCCNCc1ccccn1 -US07538120B2,6,COC(=O)c1cn2c(C#C[Si](C)(C)C)cnc2c(F)c1Nc1ccc(C)cc1F>>C#Cc1cnc2c(F)c(Nc3ccc(C)cc3F)c(C(=O)OC)cn12 -US09073914B2,3,O=c1cc(-c2ccncn2)nc2n1CCCCC2Br.[Mg+]C1CC1>>O=c1cc(-c2ccncn2)nc2n1CCCCC2C1CC1 -US08063046B2,2,CCOC(=O)c1ccc(OC)c(C(=O)[O-])c1.Nc1ccc(Cl)cc1>>CCOC(=O)c1ccc(OC)c(C(=O)Nc2ccc(Cl)cc2)c1 -US06028032,6,COCC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)OC(C)(C)C)CO1>>COCC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)O)CO1 -US20150210720A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1CC2(CCC2)N1>>CC(C)(C)OC(=O)N1C(=O)CC12CCC2 -US07666898B2,1,BrCc1ccccc1.Cc1cc2c(O)cccc2n1Cc1ccccc1>>Cc1cc2c(OCc3ccccc3)cccc2n1Cc1ccccc1 -US20150175615A1,6,C[C@@H]1CN(C2CN(C(c3ccccc3)c3ccccc3)C2)CCN1C>>C[C@@H]1CN(C2CNC2)CCN1C -US20150203511A1,3,CC[Mg+].COc1ccc(C(=O)N(C)OC)cc1C>>CCC(=O)c1ccc(OC)c(C)c1 -US09133168B2,2,CCC1Cc2ccccc2N1.O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1>>CCC1Cc2ccccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 -US20120196824A1,3,CB1OB(C)OB(C)O1.CCN(CCNC(=O)CN(CC(=O)N(C)N1Cc2ccccc2C1)c1cc2c(I)nn(C)c2cc1C)C(=O)OC(C)(C)C>>CCN(CCNC(=O)CN(CC(=O)N(C)N1Cc2ccccc2C1)c1cc2c(C)nn(C)c2cc1C)C(=O)OC(C)(C)C -US20110257151A1,1,CC1(C)Cc2cc(C#N)ccc2NC1c1cccc(N)c1.COC(=O)C(C)(C)Br>>COC(=O)C(C)(C)Nc1cccc(C2Nc3ccc(C#N)cc3CC2(C)C)c1 -US20060199817A1,9,NO.O=Cc1ccc(Cl)c(I)c1F>>ON=Cc1ccc(Cl)c(I)c1F -US20150210686A1,3,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=c1[nH]c(-c2ccc(Br)cc2)cc2ccc(F)cc12>>Cn1cc(-c2ccc(-c3cc4ccc(F)cc4c(=O)[nH]3)cc2)cn1 -US20120283260A1,2,CC(=O)Nc1ccc(CCC(=O)O)cc1.Cc1cc(OCc2ccccn2)c2cccc(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)c2n1>>CC(=O)Nc1ccc(CCC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OCc5ccccn5)cc(C)nc34)c2Cl)cc1 -US05120738,2,CC(=O)OCC(C)(C)C(OC(C)=O)C(=O)NCCC(=O)O.Nc1ccc(O)cc1>>CC(=O)OCC(C)(C)C(OC(C)=O)C(=O)NCCC(=O)Nc1ccc(O)cc1 -US07951806B2,3,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.COC(=O)c1cc(Br)ccc1NC(=O)COCC(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>COC(=O)c1cc(-c2cnn(C(=O)OC(C)(C)C)c2)ccc1NC(=O)COCC(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1 -US20040067531A1,3,COc1ccccc1-c1ccc2c(c1)NC(=O)C2.O=Cc1[nH]c2c(c1CCC(=O)O)CCCC2>>COc1ccccc1-c1ccc2c(c1)NC(=O)C2=Cc1[nH]c2c(c1CCC(=O)O)CCCC2 -US20030114666A1,7,COC(=O)C1CC(=O)N(C(C)c2ccccc2)C1>>C[C@@H](c1ccccc1)N1CC(CO)CC1=O -US06353025B1,1,CCOC(=O)CNc1ccc(CCO)cc1.CI>>CCOC(=O)CN(C)c1ccc(CCO)cc1 -US07994333B2,7,O=[N+]([O-])c1cccc2c1CCC2>>Nc1cccc2c1CCC2 -US08476253B2,2,CNCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1.COC(=O)c1ccc(CN(Cc2ccc(C(=O)O)cc2)C(=O)OC(C)(C)C)cc1>>COC(=O)c1ccc(CN(Cc2ccc(C(=O)N(C)CCN3CCC(OC(=O)Nc4ccccc4-c4ccccc4)CC3)cc2)C(=O)OC(C)(C)C)cc1 -US06376491B1,6,CCOC(=O)c1oc2cccc(OCCCNC3CCN(Cc4ccccc4)CC3)c2c1C>>CCOC(=O)c1oc2cccc(OCCCNC3CCNCC3)c2c1C -US20100120806A1,1,Cc1cc(N)ccc1O.Clc1ccnc(Cl)c1>>Cc1cc(N)ccc1Oc1ccnc(Cl)c1 -US20090044345A1,1,CN.COc1c(C)cnc(CCl)c1C>>CNCc1ncc(C)c(OC)c1C -US20090075995A1,2,CC(=O)c1ccc(C(=O)O)cc1.CNC>>CC(=O)c1ccc(C(=O)N(C)C)cc1 -US20020016506A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc([N+](=O)[O-])c2ccccc12>>CC(C)(C)OC(=O)Nc1ccc([N+](=O)[O-])c2ccccc12 -US20120022043A1,9,N.O=C(Nc1cnoc1-c1ccccc1C(F)(F)F)c1cnn2ccc(Cl)nc12>>Nc1ccn2ncc(C(=O)Nc3cnoc3-c3ccccc3C(F)(F)F)c2n1 -US20020173526A1,1,ICCCCc1ccc(OCc2ccccc2)cc1.OCC(O)Cc1ncc[nH]1>>OCC(O)Cc1nccn1CCCCc1ccc(OCc2ccccc2)cc1 -US20040082611A1,7,COC(=O)CC1CN(S(=O)(=O)c2cc3cc(Cl)ccc3n2S(=O)(=O)c2ccccc2)CCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc3cc(Cl)ccc3n2S(=O)(=O)c2ccccc2)CC1CCO -US20010051631A1,2,NCCCCn1c(=O)c2cccc3ncc(c1=O)n32.O=S(=O)(Cl)CC(F)(F)F>>O=c1c2cccc3ncc(c(=O)n1CCCCNS(=O)(=O)CC(F)(F)F)n32 -US20120122846A1,7,CCCNC(=O)c1ccc([N+](=O)[O-])cc1>>CCCNC(=O)c1ccc(N)cc1 -US08501732B2,2,NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O.O=C(O)c1ccn(Cc2ccccc2Cl)c(=O)c1>>O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccn(Cc2ccccc2Cl)c(=O)c1 -US20120129840A1,3,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl.Cc1ccc(B(O)O)c(Cl)c1>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1ccc(C)cc1Cl -US20110144033A1,1,BrCc1ccccc1.CC(C)(C)OC(=O)NN[C@@H](CC(N)=O)C(=O)O>>CC(C)(C)OC(=O)NN[C@@H](CC(N)=O)C(=O)OCc1ccccc1 -US20060183906A1,1,CNC1CCCN(Cc2ccccc2)C1.Clc1ccnc2[nH]ccc12>>CN(c1ccnc2[nH]ccc12)C1CCCN(Cc2ccccc2)C1 -US20100144760A1,6,CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2C[C@H]1CNc1ncc(C(F)(F)F)cn1>>FC(F)(F)c1cnc(NC[C@@H]2C[C@H]3C[C@H]3CN2)nc1 -US06703397B2,2,CCOc1cc(Cc2cnc(N)nc2N)cc2[nH]ccc12.CN(C)S(=O)(=O)Cl>>CCOc1cc(Cc2cnc(N)nc2N)cc2c1ccn2S(=O)(=O)N(C)C -US08680108B2,1,CC(=O)c1nc(C)c2ccccc2c1-c1cccc(F)c1.[NH4+]>>Cc1nc(C(C)N)c(-c2cccc(F)c2)c2ccccc12 -US20140378897A1,2,NCCO.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C(NCCO)c1ccc([N+](=O)[O-])cc1 -US07468376B2,1,CN.Fc1ccc(-c2nc3nn(CCCCl)cc3c(-c3ccc(F)cc3)c2-c2ccncc2)cc1>>CNCCCn1cc2c(-c3ccc(F)cc3)c(-c3ccncc3)c(-c3ccc(F)cc3)nc2n1 -US20040044041A1,3,N#Cc1ccc(B(O)O)cc1.O=Cc1ccccc1Br>>N#Cc1ccc(-c2ccccc2C=O)cc1 -US08889698B2,4,COc1cc(N)c(C(N)=O)c(OC)c1.O=Cc1ccccc1Cl>>COc1cc(OC)c2c(=O)[nH]c(-c3ccccc3Cl)nc2c1 -US20150158865A1,1,CI.C[C@@H]1[C@H](N2CCNC2=O)CCCN1C(=O)OCc1ccccc1>>C[C@@H]1[C@H](N2CCN(C)C2=O)CCCN1C(=O)OCc1ccccc1 -US20110028520A1,7,CC(C)(NC1=C[C@H](c2cccc(OC(F)(F)F)c2)N(c2ccc(OC(F)(F)F)cc2)C1=O)c1cccc(C(F)(F)F)n1>>CC(C)(N[C@@H]1C[C@H](c2cccc(OC(F)(F)F)c2)N(c2ccc(OC(F)(F)F)cc2)C1=O)c1cccc(C(F)(F)F)n1 -US20100317652A1,2,CC(C)(C)OC(=O)N1CCC(C(=O)NN)CC1.O=C(Cl)CCl>>CC(C)(C)OC(=O)N1CCC(C(=O)NNC(=O)CCl)CC1 -US20120034270A1,7,FC(F)(F)c1ccccc1-c1ccc(-c2nc(-c3cccc4[nH]ccc34)no2)cc1>>FC(F)(F)c1ccccc1-c1ccc(-c2nc(-c3cccc4c3CCN4)no2)cc1 -US20070225349A1,1,COc1ccc(-c2n[nH]c3c(Cl)cccc23)cc1.FC(F)(F)CCI>>COc1ccc(-c2nn(CCC(F)(F)F)c3c(Cl)cccc23)cc1 -US07067534B1,1,CCC(=O)Nc1cccc(C2CCNCC2)c1.CCn1c2ccccc2c2cc(C=O)ccc21>>CCC(=O)Nc1cccc(C2CCN(Cc3ccc4c(c3)c3ccccc3n4CC)CC2)c1 -US05668161,4,CSc1ccc(C(Br)C(=O)c2ccc(F)cc2)cc1.NC(=S)c1ccccc1Cl>>CSc1ccc(-c2sc(-c3ccccc3Cl)nc2-c2ccc(F)cc2)cc1 -US20150087637A1,2,N[C@@]1(c2ccc(F)cc2F)COCC[C@H]1CO.O=C(N=C=S)OCC1c2ccccc2-c2ccccc21>>O=C(NC(=S)N[C@@]1(c2ccc(F)cc2F)COCC[C@H]1CO)OCC1c2ccccc2-c2ccccc21 -US06410539B1,3,COC(=O)c1ccc(Br)c(C(=O)OC)c1.Fc1ccc(C[Zn+])cc1>>COC(=O)c1ccc(Cc2ccc(F)cc2)c(C(=O)OC)c1 -US07223752B2,3,CCOC(=O)c1ccc(Br)cc1.Cc1cccc(B(O)O)c1>>CCOC(=O)c1ccc(-c2cccc(C)c2)cc1 -US06323209B1,2,CC#CC(=O)O.CN(C)C=Nc1ccc(N)cc1C#N>>CC#CC(=O)Nc1ccc(N=CN(C)C)c(C#N)c1 -US06753340B2,2,C[C@H](N)C(=O)OC(C)(C)C.O=C(O)c1ccc2c(=O)[nH]cnc2c1>>C[C@H](NC(=O)c1ccc2c(=O)[nH]cnc2c1)C(=O)OC(C)(C)C -US05864039,1,BrCCCCBr.Sc1ccccc1>>BrCCCCSc1ccccc1 -US07230020B2,2,Cc1c(Cl)cccc1S(=O)(=O)Cl.Nc1ccc2ncncc2c1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc2ncncc2c1 -US05322939,2,CCCCCCCC(O)C#CC(C)(C)NS(=O)(=O)c1ccc(C)cc1.COC(=O)Cl>>CCCCCCCC(C#CC(C)(C)NS(=O)(=O)c1ccc(C)cc1)OC(=O)OC -US07179835B2,6,CC(C)N(CCNC(=O)OC(C)(C)C)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O>>CC(C)N(CCN)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O -US07074796B2,4,NNc1ccc(F)cc1.O=CCCCCCl>>Fc1ccc2[nH]cc(CCCCl)c2c1 -US20090247559A1,6,CC(C)(C)OC(=O)N1CCCC(c2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)C1>>O=c1[nH]c(C2CCCNC2)nc2c1oc1ccc(Br)cc12 -US08217063B2,1,CN1CCCNC1=O.COC(=O)c1ccc(CCC(/C=C/c2ccccc2OCCCCCCl)Cc2ccc(C(=O)OC)cc2)cc1>>COC(=O)c1ccc(CCC(/C=C/c2ccccc2OCCCCCN2CCCN(C)C2=O)Cc2ccc(C(=O)OC)cc2)cc1 -US07498325B2,6,CC(C)(C)OC(=O)N[C@H](Cc1cc(Br)c(N)c(Br)c1)CN1CCC(N2CCCCC2)CC1>>Nc1c(Br)cc(C[C@@H](N)CN2CCC(N3CCCCC3)CC2)cc1Br -US20140356322A1,7,Cc1ncsc1-c1ccc(C#N)c(O)c1>>Cc1ncsc1-c1ccc(CN)c(O)c1 -US20100280002A1,7,COC(=O)/C=C/c1cc(C)cc(NC(C)=O)n1>>COC(=O)CCc1cc(C)cc(NC(C)=O)n1 -US04261990,1,N#CCCl.c1ccc(C(OC2CCNCC2)c2ccccc2)cc1>>N#CCN1CCC(OC(c2ccccc2)c2ccccc2)CC1 -US20090270412A1,1,CC(=CBr)c1ccc(F)c(F)c1.Cc1ccc2[nH]c3c(c2c1)CCN(C)C3>>CC(=Cn1c2c(c3cc(C)ccc31)CCN(C)C2)c1ccc(F)c(F)c1 -US07388011B2,1,ClCC1CO1.Clc1ccc(-c2cc[nH]n2)cc1Cl>>Clc1ccc(-c2ccn(CC3CO3)n2)cc1Cl -US20070259965A1,9,CC[C@H](N=[N+]=[N-])[C@H](O)CNC(=O)OC(C)(C)C>>CC[C@H](N)[C@H](O)CNC(=O)OC(C)(C)C -US09156840B2,1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1.O=c1n(CCCCl)c2ccccc2n1C1CC1>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCn4c(=O)n(C5CC5)c5ccccc54)CC3)C2=O)c1 -US20030186970A1,1,O=CC(F)(F)F.O=[N+]([O-])c1ccc2c(c1)OCCN2>>O=[N+]([O-])c1ccc2c(c1)OCCN2CC(F)(F)F -US20140094474A1,6,CCOC(C)(C)c1nc(C(=O)OC)cn1COCC[Si](C)(C)C>>CCOC(C)(C)c1nc(C(=O)O)cn1COCC[Si](C)(C)C -US07629363B2,2,Cc1ccc(C(=O)O)cc1-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O.NCCO>>Cc1ccc(C(=O)NCCO)cc1-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O -US08263588B2,2,CC1(C)CCNc2ccccc21.O=S(=O)(Cl)c1cc(Br)c(Cl)cc1F>>CC1(C)CCN(S(=O)(=O)c2cc(Br)c(Cl)cc2F)c2ccccc21 -US20120088746A1,6,COC(=O)c1ccc2cc(C(C)(OC)C(F)(F)F)ccc2c1>>COC(C)(c1ccc2cc(C(=O)O)ccc2c1)C(F)(F)F -US20080242596A1,1,CCc1ccc(Cc2cc([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c(COCCO)cc2Cl)cc1.CI>>CCc1ccc(Cc2cc([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c(COCCOC)cc2Cl)cc1 -US20060173039A1,6,CCCN(CCC)Cc1cc(-c2c[nH]c(=O)c3cccc(O)c23)ccc1OC>>CCCN(CCC)Cc1cc(-c2c[nH]c(=O)c3cccc(O)c23)ccc1O -US20120235888A1,3,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(Cl)ccc1-c1ccc(Br)c2ccccc12>>COC=Cc1cc(Cl)ccc1-c1ccc(Br)c2ccccc12 -US20130252890A1,1,CC(C)(O)CNCCCS(=O)CCC(F)(F)F.Oc1ccc2c(c1)CCCC(c1cc(F)cc(F)c1)=C2CCCCCCBr>>CC(C)(O)CN(CCCCCCC1=C(c2cc(F)cc(F)c2)CCCc2cc(O)ccc21)CCCS(=O)CCC(F)(F)F -US20130237525A1,7,CCOC(=O)c1cccc(-c2cscn2)c1>>OCc1cccc(-c2cscn2)c1 -US20080027050A1,1,COc1cccc(CNC(=O)c2nc3cccc(F)c3c(=O)[nH]2)c1.O=C(O)c1ccc(CCO)cc1>>COc1cccc(CNC(=O)c2nc3cccc(OCCc4ccc(C(=O)O)cc4)c3c(=O)[nH]2)c1 -US20100190787A1,7,O=[N+]([O-])c1ccc(C(O)CN2CCCCC2)cc1>>Nc1ccc(C(O)CN2CCCCC2)cc1 -US05117000,3,C=O.CC(C)c1ccc(C(N)=O)cc1.c1ccsc1>>CC(C)c1ccc(C(=O)NCc2cccs2)cc1 -US05196570,7,CCCCCCCCC(/C=C/C=C/c1ccccc1CCCCCO)OC(C)=O>>CCCCCCCCC(O)/C=C/C=C/c1ccccc1CCCCCO -US20120040953A1,6,COC(=O)[C@@H](C)OC1CN(C(=O)OC(C)C)C1>>CC(C)OC(=O)N1CC(O[C@H](C)C(=O)O)C1 -US20070112059A1,9,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O.N>>CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(N)=O -US06110962,1,COC(=O)[C@@H](O)Cc1ccccc1.Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br>>COC(=O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br -US06432950B1,1,CCc1cc2c(Cl)nc(-c3ccccn3)nc2s1.NCCc1ccc2c(c1)OCO2>>CCc1cc2c(NCCc3ccc4c(c3)OCO4)nc(-c3ccccn3)nc2s1 -US20120129855A1,7,CC(C)(C)OC(=O)N1CCC(OCC(=O)N2CCCC2)CC1>>CC(C)(C)OC(=O)N1CCC(OCCN2CCCC2)CC1 -US08604030B2,1,CC(=O)N1c2cc3c(cc2C(N)CC1C)OCO3.OB(O)c1ccc(Cl)cc1>>CC(=O)N1c2cc3c(cc2[C@H](Nc2ccc(Cl)cc2)C[C@@H]1C)OCO3 -US06211227B1,7,COc1ccc2c(c1)SCc1cccc([N+](=O)[O-])c1C2=O>>COc1ccc2c(c1)SCc1cccc(N)c1C2=O -US20080171770A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(N)c1ccc(O)cc1>>CC(NC(=O)OC(C)(C)C)c1ccc(O)cc1 -US20150158878A1,7,O=C(Nc1nc2cc3c(cc2[nH]1)OC(F)(F)O3)c1cc([N+](=O)[O-])c[nH]1>>Nc1c[nH]c(C(=O)Nc2nc3cc4c(cc3[nH]2)OC(F)(F)O4)c1 -US08071592B2,6,COc1cnc2ccc(=O)n(CCN3CCO[C@@H](CNC(=O)OC(C)(C)C)C3)c2c1>>COc1cnc2ccc(=O)n(CCN3CCO[C@@H](CN)C3)c2c1 -US20060229317A1,6,Cc1nc2cc(OCC(O)CN3CCN(C(=O)OC(C)(C)C)CC3)ccc2s1>>Cc1nc2cc(OC[C@H](O)CN3CCNCC3)ccc2s1 -US04927838,3,CCCCCc1c(C=O)sc2cc(OC)ccc12.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCc1c(/C=C/C(=O)OC)sc2cc(OC)ccc12 -US05935959,2,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.Clc1ccccc1N1CCNCC1>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCN(c2ccccc2Cl)CC1 -US08592594B2,6,COC(=O)c1ccc2c(c1)C(C)(C)CC(c1cccc(N3CCOCC3)c1)N2>>CC1(C)CC(c2cccc(N3CCOCC3)c2)Nc2ccc(C(=O)O)cc21 -US20120114765A1,2,NCCN1CCN(Cc2ccccc2)CC1.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(NCCN1CCN(Cc2ccccc2)CC1)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US07732446B1,2,C1CCNC1.COc1cc2c(C(=O)O)cnc(CNC(=O)OC(C)(C)C)c2cc1OC>>COc1cc2c(C(=O)N3CCCC3)cnc(CNC(=O)OC(C)(C)C)c2cc1OC -US20080207619A1,2,COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1I.O=C(Cl)CCl>>COc1cc(C(C)C)c(Oc2cnc(NC(=O)CCl)nc2N)cc1I -US08680108B2,1,COC[C@H]1CCCN1c1c(C(C)=O)cc(Cl)c2cccnc12.[NH4+]>>COC[C@H]1CCCN1c1c(C(C)N)cc(Cl)c2cccnc12 -US04066773,2,COCCN(CC(=O)Cl)C(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c1ccc2cc(OC)c(OC)cc2c1.Cc1cccc(O)c1>>COCCN(CC(=O)Oc1cccc(C)c1)C(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c1ccc2cc(OC)c(OC)cc2c1 -US20120214762A1,3,C#C[C@@](C)(O)c1noc(C)n1.CC(C)(F)c1nn(-c2ccnc(N)n2)c2cc(Br)ccc12>>Cc1nc([C@](C)(O)C#Cc2ccc3c(C(C)(C)F)nn(-c4ccnc(N)n4)c3c2)no1 -US04081545,6,CCOC(=O)c1cnc2ncnn2c1O>>O=C(O)c1cnc2ncnn2c1O -US04885307,1,CCCCCO.O=C1C=CC(O)N1>>CCCCCOC1C=CC(=O)N1 -US04309547,1,CC(Cl)C(=O)O.Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1>>CC(Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)C(=O)O -US08450319B2,1,CCO.C[Si](C)(C)CCOCn1c(Br)c(CBr)c2c(=O)[nH]ncc21>>CCOCc1c(Br)n(COCC[Si](C)(C)C)c2cn[nH]c(=O)c12 -US03948947,1,CONC1c2ccccc2Oc2ccccc21.O=C(Cl)Cl>>CON(C(=O)Cl)C1c2ccccc2Oc2ccccc21 -US04048326,2,CC(C)OC(=O)Cl.Nc1ccc(N)c([N+](=O)[O-])c1>>CC(C)OC(=O)Nc1ccc(N)c([N+](=O)[O-])c1 -US20040116374A1,1,CCN.Nc1nc(I)nc2c1nc(Br)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>CCNc1nc2c(N)nc(I)nc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O -US20070149570A1,2,N#Cc1ccc(-c2ccc(OC(F)(F)F)c(CN[C@H]3CCNC[C@H]3c3ccccc3)c2)c(F)c1.O=C(O)CN1C(=O)COC1=O>>N#Cc1ccc(-c2ccc(OC(F)(F)F)c(CN[C@H]3CCN(C(=O)CN4C(=O)COC4=O)C[C@H]3c3ccccc3)c2)c(F)c1 -US20130040930A1,6,COc1ccc(CN2C[C@@H](C)N(c3ccc(C(=O)N4CCN(c5ncc(C)cc5C)CC4)cn3)C2=O)cc1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)NC[C@H]4C)nc3)CC2)c(C)c1 -US07119203B2,8,CC(C)(C)OC(=O)C1(S(=O)(=O)N2CCC(CCCO)CC2)CCOCC1>>CC(C)(C)OC(=O)C1(S(=O)(=O)N2CCC(CCC=O)CC2)CCOCC1 -US05962473,2,CC(C)N=C=O.CN1CCC(c2c[nH]c3ccc(N)cc23)CC1>>CC(C)NC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2c1 -US20070135489A1,6,COC(=O)c1ccccc1NCc1ccc(=O)[nH]c1>>O=C(O)c1ccccc1NCc1ccc(=O)[nH]c1 -US20030004172A1,7,CCOC(=O)c1cc([N+](=O)[O-])c(C(=O)OCC)s1>>CCOC(=O)c1cc(N)c(C(=O)OCC)s1 -US20110124636A1,2,Cc1cccc(-c2sc(C)nc2C(=O)O)c1.O=C(NC[C@@H]1C[C@@H]2C[C@@H]2N1)c1cccc2c1OCCO2>>Cc1cccc(-c2sc(C)nc2C(=O)N2[C@H](CNC(=O)c3cccc4c3OCCO4)C[C@@H]3C[C@@H]32)c1 -US06762321B2,2,CC(=O)Cl.COc1cc(CCNC(=O)C(=COC(F)F)c2ccc3c(c2)CCCC3)ccc1O>>COc1cc(CCNC(=O)C(=COC(F)F)c2ccc3c(c2)CCCC3)ccc1OC(C)=O -US06008230,6,CCOC(=O)Cc1ccnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc12>>O=C(O)Cc1ccnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc12 -US04115416,6,CCCCCC(Oc1ccc(C2=CCCCC2)cc1)C(=O)OCC>>CCCCCC(Oc1ccc(C2=CCCCC2)cc1)C(=O)O -US04328380,3,CC(CCl)Cc1ccccc1.CCC(C)(Cl)CC>>CCC(C)(CC)c1ccc(CC(C)CCl)cc1 -US07186724B2,1,CC[C@@H]1CC[C@@H](NC(=O)[C@@H]2C[C@H]2COS(C)(=O)=O)CC1.FC(F)(F)c1cnc(N2CCNCC2)c(Cl)c1>>CC[C@@H]1CC[C@@H](NC(=O)[C@@H]2C[C@H]2CN2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)CC1 -US08217051B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1Nc2cc(Cl)ccc2/C1=C/c1cccc(F)c1>>CC(C)(C)OC(=O)N1C(=O)/C(=C\c2cccc(F)c2)c2ccc(Cl)cc21 -US20030187254A1,4,COC(=O)CSC.Nc1ccc(C(F)(F)F)cc1>>CSC1C(=O)Nc2ccc(C(F)(F)F)cc21 -US08680122B2,4,COc1ccc(CN)cc1.O=C1C=C(c2ccccc2)C(=O)O1>>COc1ccc(CN2C(=O)C=C(c3ccccc3)C2=O)cc1 -US08916560B2,6,COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCCC3C)nc2c1>>CC1CCCN1c1nc2cc(C(=O)O)ccc2nc1-c1ccccc1 -US20150197509A1,1,CC1CCCN1.Clc1ncc(Br)cn1>>CC1CCCN1c1ncc(Br)cn1 -US04680301,1,CC(C)(C)c1nc2cc(Cl)c([N+](=O)[O-])cc2s1.c1ccc(N2CCNCC2)cc1>>CC(C)(C)c1nc2cc(N3CCN(c4ccccc4)CC3)c([N+](=O)[O-])cc2s1 -US20140200216A1,6,C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(Cc2ccccc2)C1>>C[C@H]1CNC[C@@H](NC(=O)OC(C)(C)C)C1 -US20080176830A1,3,O=C1CCc2cc(Br)ccc2N1.OB(O)c1ccc(C(F)(F)F)c(Cl)c1>>O=C1CCc2cc(-c3ccc(C(F)(F)F)c(Cl)c3)ccc2N1 -US03969526,1,Clc1ccncc1.Nc1cc(O)ccc1[N+](=O)[O-]>>Nc1cc(Oc2ccncc2)ccc1[N+](=O)[O-] -US04945106,2,CCOC(=O)c1ccc(F)cc1.NN>>NNC(=O)c1ccc(F)cc1 -US07968560B2,3,CN(Cc1cc(-c2ccc(C=O)cc2)cs1)C(=O)c1ccccc1.O=C1CSC(=O)N1>>CN(Cc1cc(-c2ccc(C=C3SC(=O)NC3=O)cc2)cs1)C(=O)c1ccccc1 -US07737166B2,2,CCOC(=O)CCN.O=C(Cl)OCc1ccccc1>>CCOC(=O)CCNC(=O)OCc1ccccc1 -US20040024230A1,3,CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@@]21C.C[S+](C)(C)=O>>CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@@]21C -US07910595B2,2,C=CCN[C@@H](C)c1ccccc1.CC(C)c1ccc2c(Nc3cc(C(=O)O)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1>>C=CCN(C(=O)c1ccc(Sc2ccc(NC(=O)OC(C)(C)C)cc2)c(Nc2ncnc3nc(C(C)C)ccc23)c1)[C@@H](C)c1ccccc1 -US20140088080A1,7,Cc1cccc(/C=C/C(=O)OC(C)(C)C)c1CO>>Cc1cccc(CCC(=O)OC(C)(C)C)c1CO -US06555584B1,2,Nc1ccccc1S(N)(=O)=O.O=C(O)c1ccc([N+](=O)[O-])c(OCc2ccccc2)c1>>NS(=O)(=O)c1ccccc1NC(=O)c1ccc([N+](=O)[O-])c(OCc2ccccc2)c1 -US20080076924A1,2,CC(=O)O.CC(C)C1CN(c2ccc(N)nn2)CCN1C(=S)Nc1cccc2ncccc12>>CC(=O)Nc1ccc(N2CCN(C(=S)Nc3cccc4ncccc34)C(C(C)C)C2)nn1 -US06239131B1,1,Cc1ccc2c(c1)NC(=O)C(NC(=O)OC(C)(C)C)CN2C(=O)C1CCCCC1.Cc1ccccc1C(=O)CBr>>Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(NC(=O)OC(C)(C)C)CN2C(=O)C1CCCCC1 -US08193203B2,1,CCN(CC)CCCNc1nc(NC2CCNCC2)c2ccccc2n1.Cn1ccc2cccc(C=O)c21>>CCN(CC)CCCNc1nc(NC2CCN(Cc3cccc4ccn(C)c34)CC2)c2ccccc2n1 -US05981533,6,CC(=O)Nc1ccc(CNc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1>>Nc1ccc(CNc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1 -US06498151B2,3,CCOP(=O)(OCC)C(F)(F)c1ccc(CSCc2ccc(Br)cc2)cc1Br.c1cncc(B2OCCCO2)c1>>CCOP(=O)(OCC)C(F)(F)c1ccc(CSCc2ccc(-c3cccnc3)cc2)cc1Br -US20050107392A1,6,CCOC(=O)C[C@@H]1CCc2cc(OCCc3nc(-c4ccc(C)c(N(C)C)c4)oc3C)ccc21>>Cc1ccc(-c2nc(CCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(C)o2)cc1N(C)C -US20070299113A1,3,CC1(C)OB(c2cccc(CO)c2)OC1(C)C.O=S(=O)(Oc1csc2nc(C34CC5CC(CC(C5)C3)C4)cn12)C(F)(F)F>>OCc1cccc(-c2csc3nc(C45CC6CC(CC(C6)C4)C5)cn23)c1 -US07368471B2,1,Brc1ccc2[nH]ccc2c1.CC(C)(C)c1ccc(CBr)cc1>>CC(C)(C)c1ccc(Cn2ccc3cc(Br)ccc32)cc1 -US08293734B2,1,Fc1ccc(Br)cn1.O=[N+]([O-])c1cn2c(n1)OCC(CO)C2>>O=[N+]([O-])c1cn2c(n1)OCC(COc1ccc(Br)cn1)C2 -US20110015234A1,1,CCOC(=O)c1n[nH]c2ccc(F)cc12.FC(F)Oc1ccc(CCl)cc1>>CCOC(=O)c1nn(Cc2ccc(OC(F)F)cc2)c2ccc(F)cc12 -US20030220402A1,4,N#Cc1ccccc1NC(=O)c1ccc(Oc2ccc3ccccc3c2)cc1.[N-]=[N+]=[N-]>>O=C(Nc1ccccc1-c1nnn[nH]1)c1ccc(Oc2ccc3ccccc3c2)cc1 -US20030087920A1,2,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ccncc2)nc1OCC#CCO.O=C=Nc1ccccc1>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ccncc2)nc1OCC#CCOC(=O)Nc1ccccc1 -US20130040930A1,1,CN1CCNC1=O.Cc1cnc(N2CCN(C(=O)c3cnc(Br)cn3)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3cnc(N4CCN(C)C4=O)cn3)CC2)c(C)c1 -US06806274B1,2,COc1cc2ncnc(N)c2cc1OC.O=C=Nc1c(Cl)cccc1Cl>>COc1cc2ncnc(NC(=O)Nc3c(Cl)cccc3Cl)c2cc1OC -US08088930B2,1,N#Cc1ccc(O)c(F)c1.OCC(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21>>N#Cc1ccc(OCC(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(F)c1 -US04608375,1,Cn1c(=O)nc(Cl)c2ccccc21.NCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1>>Cn1c(=O)nc(NCCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)c2ccccc21 -US20140275172A1,1,CCOC(=O)CCc1ccc(O)c(C)c1C.CCc1cc2cc(Cl)c(C)c(CO)c2o1>>CCOC(=O)CCc1ccc(OCc2c(C)c(Cl)cc3cc(CC)oc23)c(C)c1C -US20130109678A1,1,NN1CCOCC1.Nc1cc(Cl)ccc1[N+](=O)[O-]>>Nc1cc(NN2CCOCC2)ccc1[N+](=O)[O-] -US20100216762A1,1,O=C(O)C1CNC1.O=Cc1ccc(C(=O)Cc2ccccc2)cc1>>O=C(Cc1ccccc1)c1ccc(CN2CC(C(=O)O)C2)cc1 -US20090029958A1,4,C[S+](C)(C)=O.O=C1CCN(CCOCCc2cccc(Cl)c2Cl)CC1>>Clc1cccc(CCOCCN2CCC3(CC2)CO3)c1Cl -US07176227B2,1,CCCN(CCC)CCCCC1Cc2cc(CNCc3ncc[nH]3)ccc2C1OC.Cn1ccnc1C=O>>CCCN(CCC)CCCCC1Cc2cc(CN(Cc3ncc[nH]3)Cc3nccn3C)ccc2C1OC -US08598347B2,6,CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)Cc1cc(F)c(F)cc1F>>CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)c(F)cc1F -US20110237581A1,7,O=C1OCc2c1cccc2[N+](=O)[O-]>>Nc1cccc2c1COC2=O -US04742057,7,CCC(=O)Nc1nc(CN2CCC(c3c[nH]c4ccc([N+](=O)[O-])cc34)CC2)cs1>>CCC(=O)Nc1nc(CN2CCC(c3c[nH]c4ccc(N)cc34)CC2)cs1 -US05352792,6,CC/C=C(\C(=O)OC)c1csc(NC(=O)OC(C)(C)C)n1>>CC/C=C(\C(=O)O)c1csc(NC(=O)OC(C)(C)C)n1 -US08946260B2,7,N#CCc1csc2ccc(F)cc12>>NCCc1csc2ccc(F)cc12 -US20140303175A1,2,CCOC(Cc1ccc(C(C)(C)O[SiH2]C(C)(C)C)cc1)C(=O)O.OCC(Cl)(Cl)Cl>>CCOC(Cc1ccc(C(C)(C)O[SiH2]C(C)(C)C)cc1)C(=O)OCC(Cl)(Cl)Cl -US20030224006A1,9,O=c1cc(O)cc[nH]1>>O=c1cccc[nH]1 -US20100249163A1,6,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(OC)c2ccn(C)c(=O)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)[C@H]2CNCC[C@]2(OC)c2ccn(C)c(=O)c2)C2CC2)cc(OCCOC)c1 -US20120058999A1,7,CCOC(=O)C1c2cccn2CCN1S(=O)(=O)c1c(C)cccc1Cl>>Cc1cccc(Cl)c1S(=O)(=O)N1CCn2cccc2C1CO -US07273865B2,2,COc1cnc(C2CCOCC2)c2sc(N)nc12.Cc1cc(C(=O)O)ccn1>>COc1cnc(C2CCOCC2)c2sc(NC(=O)c3ccnc(C)c3)nc12 -US05348955,2,CCCCCN(CCCCC)C(=O)Cl.O=C(O)[C@@H]1CNCCN1C(=O)N(c1ccccc1)c1cccc(Cl)c1>>CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2cccc(Cl)c2)[C@H](C(=O)O)C1 -US06284785B1,2,Cc1ccc(C2CCCN2)c(C)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)N2CCCC2c2ccc(C)cc2C)cc1 -US20050234042A1,4,CC(C)(C)OC(=O)N1CCC[C@H]1C#N.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC[C@H]1c1nnn[nH]1 -US06169097A,2,Cc1cc(C)cc(C(=O)N2CC[C@@H](N3CCC(O)CC3)C[C@@H]2Cc2ccccc2)c1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>Cc1cc(C)cc(C(=O)N2CC[C@@H](N3CCC(OC(=O)c4cc(Cl)cc(Cl)c4)CC3)C[C@@H]2Cc2ccccc2)c1 -US20070208055A1,7,CC(C)[C@@H]1C[C@@H](C(=O)OCc2ccccc2)N(C(=O)OC(C)(C)C)C1=O>>CC(C)[C@@H]1C[C@@H](CO)N(C(=O)OC(C)(C)C)C1=O -US20080139631A1,3,N#Cc1ccc2c(cc(C3CC3)n2Cc2ccc(Br)o2)c1C(F)(F)F.OB(O)c1cc(F)cc(F)c1>>N#Cc1ccc2c(cc(C3CC3)n2Cc2ccc(-c3cc(F)cc(F)c3)o2)c1C(F)(F)F -US20060205732A1,6,COC(=O)c1cncc(C(=O)OC)c1OC>>COC(=O)c1cncc(C(=O)O)c1OC -US20130196983A1,2,COC(=O)Oc1cc(N)c(C#CCN(C)C)cc1C1CCCC1.O=C(O)C1CNc2cc(OC(F)(F)F)ccc2O1>>COC(=O)Oc1cc(NC(=O)C2CNc3cc(OC(F)(F)F)ccc3O2)c(C#CCN(C)C)cc1C1CCCC1 -US07709471B2,1,CI.O=C1Nc2cnc(Cl)nc2N(C2CCCC2)CC12CCCCC2>>CN1C(=O)C2(CCCCC2)CN(C2CCCC2)c2nc(Cl)ncc21 -US20050176775A1,1,CC(Br)c1ccccc1.O=c1c(Br)c(O)ccn1Cc1cccc(F)c1>>CC(Oc1ccn(Cc2cccc(F)c2)c(=O)c1Br)c1ccccc1 -US20110275622A1,7,CC(C)(C)OC(=O)Oc1ccc([C@H](CN(CCCCCCOCCCCc2ccc([N+](=O)[O-])cc2)C(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C)c2ccc(=O)[nH]c12>>CC(C)(C)OC(=O)Oc1ccc([C@H](CN(CCCCCCOCCCCc2ccc(N)cc2)C(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C)c2ccc(=O)[nH]c12 -US20040092737A1,2,CC(C)(C)OC(=O)N1CCC2(CC1)CC(CC(=O)O)C2.CN1C2CCC1CC(N)C2>>CN1C2CCC1CC(NC(=O)CC1CC3(CCN(C(=O)OC(C)(C)C)CC3)C1)C2 -US20120108574A1,3,Brc1c(-c2ccccc2)nc2n1-c1cccnc1Nc1ccccc1-2.CC(C)(C)OC(=O)NC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CCC1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1 -US08163769B2,6,CCOC(=O)c1cn(Cc2ccc(OC)cc2OC)c2nc(N3CC[C@H](NC(=O)OC(C)(C)C)C3)c(F)cc2c1=O>>COc1ccc(Cn2cc(C(=O)O)c(=O)c3cc(F)c(N4CC[C@H](NC(=O)OC(C)(C)C)C4)nc32)c(OC)c1 -US05116404,1,CCOCCl.O=c1cc(-c2ccccc2Cl)[nH]c(=O)n1-c1ccc(OC(F)(F)F)cc1>>CCOCn1c(-c2ccccc2Cl)cc(=O)n(-c2ccc(OC(F)(F)F)cc2)c1=O -US07598264B2,2,CNC.COC(=O)c1[nH]c(=O)c(O)c2c1CCN(Cc1ccc(F)cc1)C2=O>>CN(C)C(=O)c1[nH]c(=O)c(O)c2c1CCN(Cc1ccc(F)cc1)C2=O -US20100204212A1,1,CCOc1ccc(N)cc1.Clc1nn2ccnc2c(Cl)c1Cl>>CCOc1ccc(Nc2c(Cl)c(Cl)nn3ccnc23)cc1 -US20140163001A1,6,CCOC(=O)c1cnn(C(C)(C)C)c1-c1ccc(F)cc1>>CC(C)(C)n1ncc(C(=O)O)c1-c1ccc(F)cc1 -US20150210682A1,2,COCCOc1cc(CC(N)CC(C)C)ccc1Cl.O=CO>>COCCOc1cc(CC(CC(C)C)NC=O)ccc1Cl -US20110039883A1,2,CC1CCN(C(=O)Cl)CC1.O=c1[nH]c2ncc(Br)cc2o1>>CC1CCN(C(=O)n2c(=O)oc3cc(Br)cnc32)CC1 -US20140316088A1,1,CO.O=[N+]([O-])c1cccc([N+](=O)[O-])c1Br>>COc1c([N+](=O)[O-])cccc1[N+](=O)[O-] -US07989469B2,1,CCC(N)CC.N#Cc1ncc(Cl)c(I)c1F>>CCC(CC)Nc1c(C#N)ncc(Cl)c1I -US05051440,1,BrCCBr.Oc1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(OCCBr)c1 -US20030225268A1,2,C1=CC2CC1CN2.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)N1CC2C=CC1C2 -US06939874B2,6,CCOC(=O)c1cnc2ccc(OC)cc2c1>>COc1ccc2ncc(C(=O)O)cc2c1 -US20030139475A1,6,O=CNc1cc(C(O)CNCCOc2ccc3c(c2)[nH]c2ccccc23)ccc1OCc1ccccc1>>O=CNc1cc(C(O)CNCCOc2ccc3c(c2)[nH]c2ccccc23)ccc1O -US06476021B1,1,O=c1c(Cc2cccnc2)cn2c3cc(Br)ccc3c(=O)c3cc(O)cc1c32.OCCCBr>>O=c1c(Cc2cccnc2)cn2c3cc(Br)ccc3c(=O)c3cc(OCCCO)cc1c32 -US20080015203A1,2,C1CNC1.Cc1cnc(NC(=O)c2cc(Oc3ccc(C(=O)O)cc3)cc(O[C@@H](C)CO)c2)cn1>>Cc1cnc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3)cc(O[C@@H](C)CO)c2)cn1 -US07078414B2,6,CCOC(=O)c1ccn(-c2ccnc3ccccc23)c1C>>Cc1c(C(=O)O)ccn1-c1ccnc2ccccc12 -US08455477B2,6,CCc1c(C(=O)OC)cnn1-c1ccccc1>>CCc1c(C(=O)O)cnn1-c1ccccc1 -US20120220590A1,1,CS(=O)(=O)OCCc1cccs1.Cc1c(N(Cc2ccc(C#N)cc2)Cc2ccc(Oc3cccc(O)c3)cc2)cccc1[N+](=O)[O-]>>Cc1c(N(Cc2ccc(C#N)cc2)Cc2ccc(Oc3cccc(OCCc4cccs4)c3)cc2)cccc1[N+](=O)[O-] -US20090306133A1,6,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3ccncc3)nc3ccccc23)CC1>>NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3ccncc3)nc3ccccc23)CC1 -US20030096980A1,1,Brc1ccccn1.C[Sn](C)(C)Cl>>C[Sn](C)(C)c1ccccn1 -US20090233900A1,6,CN1C(=O)CCc2ccc(NC(=O)c3ccc(Cl)cc3NCC3CCCCN3C(=O)OC(C)(C)C)cc21>>CN1C(=O)CCc2ccc(NC(=O)c3ccc(Cl)cc3NCC3CCCCN3)cc21 -US07728025B2,4,Nc1cc(Oc2cccnc2)c(Cl)c(Oc2cccnc2)c1N.O=C(O)c1ccccn1>>Clc1c(Oc2cccnc2)cc2[nH]c(-c3ccccn3)nc2c1Oc1cccnc1 -US07999132B2,2,CC(C)(C)OC(=O)c1ccc(Oc2ccccc2)cc1N.COc1ccc(C=CC(=O)O)cc1OC>>COc1ccc(/C=C/C(=O)Nc2cc(Oc3ccccc3)ccc2C(=O)OC(C)(C)C)cc1OC -US20150225396A1,2,N#Cc1cccc(O[C@@H]2CC[C@@H](N)CC2)c1.O=C(O)CCCc1nc2ccccc2c(=O)[nH]1>>N#Cc1cccc(O[C@@H]2CC[C@@H](NC(=O)CCCc3nc4ccccc4c(=O)[nH]3)CC2)c1 -US05929067,6,CCOC(=O)C=CC(C(c1ccccc1)c1ccccc1)N(C)C(=O)OC(C)(C)C>>CCOC(=O)C=CC(NC)C(c1ccccc1)c1ccccc1 -US20050009784A1,3,CCCC[Sn](C#Cc1ccccc1)(CCCC)CCCC.Oc1ccc2nc(-c3ccc(O)c(F)c3)cc(Br)c2c1>>Oc1ccc2nc(-c3ccc(O)c(F)c3)cc(C#Cc3ccccc3)c2c1 -US06498151B2,10,COP(=O)(OC)c1cc(-c2ccc(C)cc2)ccc1OC(C)=O.O=C1CCC(=O)N1Br>>COP(=O)(OC)c1cc(-c2ccc(CBr)cc2)ccc1OC(C)=O -US05861401,7,COc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(NC(C)=O)cccc12>>CCNc1cccc2c(S(=O)(=O)Nc3ncc(Br)nc3OC)cccc12 -US20110009454A1,2,NCc1ccc(COc2ccccc2)cc1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1ccc(COc2ccccc2)cc1 -US20050148624A1,6,CCC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(=O)(=O)NCC(=O)OC)cc1>>CCC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(=O)(=O)NCC(=O)O)cc1 -US20070225332A1,1,CC(c1cc(-c2cnc(Oc3ccc(O)cc3Cl)s2)no1)N1C(=O)c2ccccc2C1=O.OCC1CC1>>CC(c1cc(-c2cnc(Oc3ccc(OCC4CC4)cc3Cl)s2)no1)N1C(=O)c2ccccc2C1=O -US07964591B2,1,CCOCCNC(=O)c1ccc(Cl)nn1.O=C(c1ccccc1C(F)(F)F)N1CCNCC1>>CCOCCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 -US20020193402A1,6,CCOC(=O)[C@]1(F)C[C@@]2(c3ccccc3)[C@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC[C@@H]1N2Cc1ccccc1>>CCOC(=O)[C@]1(F)C[C@]2(c3ccccc3)N[C@H]1CC[C@H]2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US04647398,1,CCC(C)COC(=O)Oc1ccc(O)cc1.CCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1>>CCCCCCCCc1ccc(-c2ccc(C(=O)Oc3ccc(OC(=O)OCC(C)CC)cc3)cc2)cc1 -US20110319379A1,6,CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cn(CC)nc2c1>>CCn1cc2c(Oc3ccc(S(C)(=O)=O)cc3)cc(C(=O)O)cc2n1 -US20100113502A1,6,Cc1oncc1Cn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(=O)OC(C)(C)C)CC2>>Cc1oncc1Cn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CNCC2 -US08258160B2,1,Cc1cc(-c2nc[nH]n2)sc1C(=O)NCc1ccccc1.Fc1ccc(CBr)cc1>>Cc1cc(-c2ncn(Cc3ccc(F)cc3)n2)sc1C(=O)NCc1ccccc1 -US05147885,6,CCCN1C(=O)N(N=CC(O)C2CCCCC2)C2CC(SCCCC(=O)OC)CC21>>CCCN1C(=O)N(N=CC(O)C2CCCCC2)C2CC(SCCCC(=O)O)CC21 -US08344163B2,7,COC(=O)CC1CCC2(CC1)OCCO2>>OCCC1CCC2(CC1)OCCO2 -US04273932,6,CCON=C1CCCc2ncc(C(=O)OCC)c(O)c21>>CCON=C1CCCc2ncc(C(=O)O)c(O)c21 -US20030082623A1,1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.COC(CCCl)c1ccc(Cl)cc1>>COC(CCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)c1ccc(Cl)cc1 -US05266570,2,NC1CCN(CC23CC(c4ccccc42)c2ccc(Cl)cc23)CC1.O=C(Cl)CC1CCCC1>>O=C(CC1CCCC1)NC1CCN(CC23CC(c4ccccc42)c2ccc(Cl)cc23)CC1 -US20120058984A1,1,OC1CCOCC1.Oc1cncc(Br)c1>>Brc1cncc(OC2CCOCC2)c1 -US20130274294A1,3,C#C[Si](C)(C)C.Cc1cncc(Br)c1>>Cc1cncc(C#C[Si](C)(C)C)c1 -US20150087658A1,1,CCCC[Sn](Cl)(CCCC)CCCC.Cn1nnc(I)n1>>CCCC[Sn](CCCC)(CCCC)c1nnn(C)n1 -US20050043336A1,1,CN1CCC(Oc2cccc3ncnc(Nc4ccc(O)c(F)c4)c23)CC1.ClCc1ccccc1>>CN1CCC(Oc2cccc3ncnc(Nc4ccc(OCc5ccccc5)c(F)c4)c23)CC1 -US20110118261A1,1,CCN[C@@H]1CCNC1.Fc1ccc(Br)cn1>>CCN[C@@H]1CCN(c2ccc(Br)cn2)C1 -US03947437,1,CN(C)C(=O)Nc1ccc(O)cc1.Clc1ccc(Cl)nn1>>CN(C)C(=O)Nc1ccc(Oc2ccc(Cl)nn2)cc1 -US20050148609A1,2,COc1ccc(C(=O)c2ccc(N)c(C(=O)c3cccc(Cl)c3)c2)cc1.O=C(Cl)C(Cl)(Cl)Cl>>COc1ccc(C(=O)c2ccc(NC(=O)C(Cl)(Cl)Cl)c(C(=O)c3cccc(Cl)c3)c2)cc1 -US20100152442A1,1,CNC.COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCN(S(=O)(=O)CCCCl)CC1>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCN(S(=O)(=O)CCCN(C)C)CC1 -US08404856B2,9,[N-]=[N+]=NCc1nn(C2CCCCO2)c2nc(F)ccc12>>NCc1nn(C2CCCCO2)c2nc(F)ccc12 -US07851492B2,4,N#Cc1cc(-c2ccccc2)ccc1NC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.[N-]=[N+]=[N-]>>O=C(Nc1ccc(-c2ccccc2)cc1-c1nnn[nH]1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US08232391B2,1,CC(C)(C)OC(=O)CBr.COc1ccc2nccc(-n3cc4c(n3)CCC(NCc3ccc5c(c3)NC(=O)CS5)C4)c2n1>>COc1ccc2nccc(-n3cc4c(n3)CCC(N(CC(=O)OC(C)(C)C)Cc3ccc5c(c3)NC(=O)CS5)C4)c2n1 -US20060293374A1,5,N#Cc1cccc(C=O)c1.OCCO>>N#Cc1cccc(C2OCCO2)c1 -US09049878B2,2,CC(C)C(=O)O.CCOC(=O)c1c(C)nc2cccc(OC[C@@H]3CCCN3)c2c1N>>CCOC(=O)c1c(C)nc2cccc(OC[C@@H]3CCCN3C(=O)C(C)C)c2c1N -US04003919,6,COC1(C)CCc2c(C)c(O)c(C)c(C)c2O1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(O)O2 -US20100210642A1,3,C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)c(Cl)c3)nc12.NS(=O)(=O)c1cc(Br)c(F)cc1F>>NS(=O)(=O)c1cc(C#Cc2cnn3c(C(F)(F)F)cc(-c4ccc(Cl)c(Cl)c4)nc23)c(F)cc1F -US20110263494A1,6,COC(=O)c1ccc(C(=O)[C@H]2CCCC3=Cc4c(-c5ccc(F)cc5)ncn4C[C@@]32C)s1>>C[C@]12Cn3cnc(-c4ccc(F)cc4)c3C=C1CCC[C@@H]2C(=O)c1ccc(C(=O)O)s1 -US08841455B2,2,CCc1nn(Cc2nc(C)cs2)c2cccc(N)c12.CN1CCN(CCOc2ccn3c(C(=O)O)cnc3c2)CC1>>CCc1nn(Cc2nc(C)cs2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)CC5)ccn34)c12 -US20080269210A1,1,CN(Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1)C(=O)CBr.CS(=O)(=O)C1CCNC1>>CN(Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1)C(=O)CN1CCC(S(C)(=O)=O)C1 -US20130225524A1,3,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(Br)ccc23)c1.OB(O)c1cncnc1>>CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4cncnc4)ccc23)c1 -US05608062,8,COc1cccc(C(O)C(F)(F)F)c1>>COc1cccc(C(=O)C(F)(F)F)c1 -US20050096309A1,9,COC(=O)CN([C@H]1CCCN(C2CCN(C(C)C)CC2)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1.N>>CC(C)N1CCC(N2CCC[C@H](N(CC(N)=O)S(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)CC1 -US20130190290A1,1,CO.O=C(O)c1cc(O)cc(S(F)(F)(F)(F)F)c1>>COc1cc(C(=O)O)cc(S(F)(F)(F)(F)F)c1 -US20050090529A1,2,CCN(Cc1cncc(-c2ccc3c(c2)c(-c2ncc(C(=O)O)[nH]2)nn3C2CCCCO2)c1C)C(=O)OC(C)(C)C.NCc1cccnc1>>CCN(Cc1cncc(-c2ccc3c(c2)c(-c2ncc(C(=O)NCc4cccnc4)[nH]2)nn3C2CCCCO2)c1C)C(=O)OC(C)(C)C -US20090170909A1,6,CC(C)(C)OC(=O)NC1(C(O)C(=O)NC2CC2)CC1>>NC1(C(O)C(=O)NC2CC2)CC1 -US20120202794A1,2,CC(C)C[C@@H]1NC[C@H](c2ccsc2)NC1=O.O=C(O)c1cc(-c2ccc(F)cc2)no1>>CC(C)C[C@H]1C(=O)N[C@@H](c2ccsc2)CN1C(=O)c1cc(-c2ccc(F)cc2)no1 -US20100035865A1,2,CC(C)S(=O)(=O)Cl.N[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1>>CC(C)S(=O)(=O)N[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1 -US20110178060A1,2,CN(C(=O)N(C)[C@@H]1CN(C(=O)C2CCNCC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C1CCOCC1>>CN(C(=O)N(C)[C@@H]1CN(C(=O)C2CCN(C(=O)C3CCOCC3)CC2)C[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 -US07741341B2,7,COC(=O)c1ccc(NCc2cc(-c3ccc(Cl)s3)on2)c([N+](=O)[O-])c1>>COC(=O)c1ccc(NCc2cc(-c3ccc(Cl)s3)on2)c(N)c1 -US20140057937A1,2,CCC(C(=O)O)n1cc(C(F)(F)F)nc1C.Fc1ccc(-n2ncc3c2CCCN3)cc1>>CCC(C(=O)N1CCCc2c1cnn2-c1ccc(F)cc1)n1cc(C(F)(F)F)nc1C -US06432950B1,1,COc1ccc(CNc2nc(Cl)nc3sc([N+](=O)[O-])cc23)cc1Cl.Cc1ncc[nH]1>>COc1ccc(CNc2nc(-n3ccnc3C)nc3sc([N+](=O)[O-])cc23)cc1Cl -US20090270418A1,6,Cc1cc(Nc2cncc(Nc3ccc(Cl)cc3)n2)nn1C(=O)OC(C)(C)C>>Cc1cc(Nc2cncc(Nc3ccc(Cl)cc3)n2)n[nH]1 -US04550107,1,CCN(CC)CC1CCCCN1.O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21>>CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2C(=O)Nc2cccnc21 -US06051712,1,CC(C)(C)OC(=O)N1CCC(c2ccc(O)cc2)C(O)C1.CS(=O)(=O)OCCOCCc1ccccc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(OCCOCCc3ccccc3)cc2)C(O)C1 -US20100168173A1,1,Cc1ccnc(CCl)c1.Nc1ccc(-c2cc(Cc3ccc(O)cc3)no2)c(N)n1>>Cc1ccnc(COc2ccc(Cc3cc(-c4ccc(N)nc4N)on3)cc2)c1 -US06265415B1,1,CCc1cccc(CC)c1C=O.Cc1nc2c(N)cccn2c1C>>CCc1cccc(CC)c1CNc1cccn2c(C)c(C)nc12 -US20070213311A1,3,CC[Mg+].O=C(C(=O)N1CCC2(C1)OC(=O)c1ccccc12)c1ccc(Br)cc1F>>CCC(O)(C(=O)N1CCC2(C1)OC(=O)c1ccccc12)c1ccc(Br)cc1F -US20090018166A1,2,CCCC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCCC1=O.Cc1ccc(CS(N)(=O)=O)cc1>>CCCC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccc(C)cc3)CC2)nc1CN1CCCCC1=O -US20110237565A1,1,CC(C)(C)OC(=O)N1CCNCC1.Clc1nccnc1Cl>>CC(C)(C)OC(=O)N1CCN(c2nccnc2Cl)CC1 -US20090227641A1,6,CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H](C)NC(=O)OC(C)(C)C)cc3)no2)cc1>>CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H](C)N)cc3)no2)cc1 -US20140187421A1,1,CC(C)C(O)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl.CCI>>CCOC(Cn1cncn1)(c1ccc(Oc2ccc(Cl)cc2)cc1Cl)C(C)C -US08354444B2,1,CC1(C)OC[C@H](CCOS(C)(=O)=O)O1.[N-]=[N+]=[N-]>>CC1(C)OC[C@H](CCN=[N+]=[N-])O1 -US20060100245A1,3,COC(=O)c1ccc(Cl)nc1.OB(O)c1ccccc1Cl>>COC(=O)c1ccc(-c2ccccc2Cl)nc1 -US07037932B2,1,O[C@H](CCCl)c1ccccc1.Oc1cccc2ccsc12>>ClCC[C@H](Oc1cccc2ccsc12)c1ccccc1 -US04853386,1,C=CCN(c1nc(Cl)nc2c1ncn2C1CCCO1)C1CCCCC1.CN>>C=CCN(c1nc(NC)nc2c1ncn2C1CCCO1)C1CCCCC1 -US20120277229A1,6,O=C(Nc1ccc2c(c1)c(-c1nc3ccccc3[nH]1)nn2C1CCCCO1)Nc1ccc(F)cc1F>>O=C(Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)Nc1ccc(F)cc1F -US20130012703A1,1,Clc1nc(Cl)c2scc(Br)c2n1.NCc1ccccc1>>Clc1nc(NCc2ccccc2)c2scc(Br)c2n1 -US07368451B2,2,Nc1ccccc1.O=C(O)COc1ccc(CCCCNC(=O)OCc2ccccc2)cc1>>O=C(COc1ccc(CCCCNC(=O)OCc2ccccc2)cc1)Nc1ccccc1 -US20100227887A1,2,CCOC(=O)c1cc(C#N)cc(C)n1.Nc1cccc(Cl)c1>>Cc1cc(C#N)cc(C(=O)Nc2cccc(Cl)c2)n1 -US20110319385A1,7,COCc1cc(N)c([N+](=O)[O-])cc1C(=O)OC>>COCc1cc(N)c(N)cc1C(=O)OC -US07015218B1,1,N#Cc1cc([N+](=O)[O-])ccc1N1CCC(=O)CC1.NCCO>>N#Cc1cc([N+](=O)[O-])ccc1N1CCC(NCCO)CC1 -US20110301211A1,3,CCOC(=O)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cc1noc(-c2ccc(Br)cc2)c1NC(=O)OC(C)c1cc(F)ccc1F>>CCOC(=O)Cc1ccc(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3cc(F)ccc3F)cc2)cc1 -US07468376B2,2,CCCN.O=C(O)CCn1ncc2c(-c3ccc(F)cc3)c(-c3ccncc3)c(-c3ccc(F)cc3)nc21>>CCCNC(=O)CCn1ncc2c(-c3ccc(F)cc3)c(-c3ccncc3)c(-c3ccc(F)cc3)nc21 -US20100075978A1,2,C(CN1CCNCC1)CN1CCOCC1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)c(Cl)c2)cc1>>O=C(c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)c(Cl)c2)cc1)N1CCN(CCCN2CCOCC2)CC1 -US20120077787A1,3,N#Cc1cc2nccn2cc1Br.OB(O)c1ccc(Cl)cc1Cl>>N#Cc1cc2nccn2cc1-c1ccc(Cl)cc1Cl -US08518972B2,1,CC(C)(C)N.COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CBr)cc3)cccc2C1=O>>COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CNC(C)(C)C)cc3)cccc2C1=O -US07479561B2,3,COc1cc(Nc2c(C#N)cnc3cc(OS(=O)(=O)C(F)(F)F)c(OC)cc23)c(Cl)cc1Cl.O=Cc1cc(B(O)O)co1>>COc1cc(Nc2c(C#N)cnc3cc(-c4coc(C=O)c4)c(OC)cc23)c(Cl)cc1Cl -US20090163462A1,1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(I)cc1.Oc1ccc(-c2ccsc2)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(Oc2ccc(-c3ccsc3)cc2)cc1 -US20100317693A1,2,CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)O.NC1Cc2cccc(N3CCCC3=O)c2N(Cc2ccsc2)C1=O>>CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)NC1Cc2cccc(N3CCCC3=O)c2N(Cc2ccsc2)C1=O -US07279470B2,2,CN(C(=O)Cl)c1ccccc1.Oc1cccc(-c2ccccc2)c1>>CN(C(=O)Oc1cccc(-c2ccccc2)c1)c1ccccc1 -US06005116,1,CC(C)(C)OC(=O)NCCO.CC(C)c1c(O)noc1-c1ccccc1Cl>>CC(C)c1c(OCCNC(=O)OC(C)(C)C)noc1-c1ccccc1Cl -US20100190761A1,1,CC(C)(C)C(c1ccc(OCc2ccccn2)cc1)c1ccc(C(=O)NC2CCNCC2)cc1.FCCBr>>CC(C)(C)C(c1ccc(OCc2ccccn2)cc1)c1ccc(C(=O)NC2CCN(CCF)CC2)cc1 -US20030144326A1,2,Nc1ccc(N2CCC(=O)CC2)cc1.O=S(=O)(Cl)c1ccc(S(=O)(=O)c2ccc(C(F)(F)F)cn2)s1>>O=C1CCN(c2ccc(NS(=O)(=O)c3ccc(S(=O)(=O)c4ccc(C(F)(F)F)cn4)s3)cc2)CC1 -US04213984,1,CC(c1ccccc1)N1CCNCC1.O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21>>CC(c1ccccc1)N1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 -US20110124642A1,2,Nn1nc(C(F)(F)F)c2ccccc2c1=O.O=C(Cl)Cc1cccs1>>O=C(Cc1cccs1)Nn1nc(C(F)(F)F)c2ccccc2c1=O -US05082848,7,Cc1cc2c(c(C)c1[N+](=O)[O-])OCO2>>Cc1cc2c(c(C)c1N)OCO2 -US06951867B2,2,CC(C)(C)OC(=O)N1CCC(CN)CC1.CCc1cn2c(N)c(Cl)cc(C(=O)O)c2n1>>CCc1cn2c(N)c(Cl)cc(C(=O)NCC3CCN(C(=O)OC(C)(C)C)CC3)c2n1 -US07132456B2,10,CCOC(=O)c1ccccc1-c1cccc(C)c1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccccc1-c1cccc(CBr)c1 -US20130261133A1,9,C=C[C@@H](C#CC#C[C@H](N)CCCCCCCCC)OC(C)=O.S=C(Cl)Cl>>C=C[C@@H](C#CC#C[C@@H](CCCCCCCCC)N=C=S)OC(C)=O -US20130190290A1,2,Cc1ccc(N)cc1-n1ccn2nc(-c3cccnc3)cc12.O=C(O)c1cc(Cl)cc(S(F)(F)(F)(F)F)c1>>Cc1ccc(NC(=O)c2cc(Cl)cc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 -US04728650,2,COc1c(C)c(C)c2c(c1C)CCC(C)(CCN1CCNCC1)O2.COc1cc(C(=O)Cl)cc(OC)c1OC>>COc1cc(C(=O)N2CCN(CCC3(C)CCc4c(C)c(OC)c(C)c(C)c4O3)CC2)cc(OC)c1OC -US06162832,1,CCOc1ccc(Cl)c([N+](=O)[O-])c1.Oc1ccc(OCc2ccccc2)cc1>>CCOc1ccc(Oc2ccc(OCc3ccccc3)cc2)c([N+](=O)[O-])c1 -US08785403B2,1,CCc1ccc(C(=O)c2ccc(Cl)nc2)cc1.OCc1ccccc1>>CCc1ccc(C(=O)c2ccc(OCc3ccccc3)nc2)cc1 -US20050131014A1,1,COc1cccc(C=O)c1OCc1ccccc1.Nc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1>>COc1cccc(CNc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1OCc1ccccc1 -US04238494,8,CSc1[nH]cc(-c2ccccc2)c1[N+](=O)[O-].OO>>CS(=O)c1[nH]cc(-c2ccccc2)c1[N+](=O)[O-] -US08008298B2,1,CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cccc(C=O)c3)nc12.c1nnc2n1CCNC2>>CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cccc(CN4CCn5cnnc5C4)c3)nc12 -US20140364433A1,1,Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.FC(F)(F)c1cccnc1Cl>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2ncccc2C(F)(F)F)c1 -US05965589,3,Cc1oc(-c2ccccc2)nc1COc1ccc2c(c1)CCC(C=O)=C2.O=C1CSC(=O)N1>>Cc1oc(-c2ccccc2)nc1COc1ccc2c(c1)CCC(C=C1SC(=O)NC1=O)=C2 -US04563446,3,O=C(O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=C(c1ccccc1)c1cccnc1>>O=C(O)CCCC/C=C(/c1ccccc1)c1cccnc1 -US08815874B2,2,CCN.CCOC(=O)c1cnc2c(S(=O)(=O)O)cnn2c1Nc1ccc(F)cc1C>>CCNS(=O)(=O)c1cnn2c(Nc3ccc(F)cc3C)c(C(=O)OCC)cnc12 -US05892094,9,N#Cc1ccccc1-c1ccc(CBr)cc1>>Cc1ccc(-c2ccccc2C#N)cc1 -US20130172328A1,6,O=c1[nH]c2cccnc2n1-c1ccc(OCc2ccccc2)cc1>>O=c1[nH]c2cccnc2n1-c1ccc(O)cc1 -US09079866B2,3,CC1(C)OB(c2ccc(-c3cnc(N)cn3)c(F)c2)OC1(C)C.O=S(=O)(c1ccccc1Br)N1CCC(CCO)CC1>>Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCC(CCO)CC3)cc2F)cn1 -US08299080B2,1,CC(=O)c1ccc(F)c([N+](=O)[O-])c1.CCOC(=O)CCc1ncc[nH]1>>CCOC(=O)CCc1nccn1-c1ccc(C(C)=O)cc1[N+](=O)[O-] -US07723527B2,1,CN1CCC(CCCOc2cc(Cl)c(C#N)cn2)CC1.C[O-]>>COc1cc(OCCCC2CCN(C)CC2)ncc1C#N -US20090227603A1,1,CCOC(=O)CCCOc1cccc(CCCCCCBr)c1CCC(=O)OCC.CCS(=O)(=O)c1cc(O)cc(Br)c1>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(S(=O)(=O)CC)c2)c1CCC(=O)OCC -US20150148332A1,3,Cc1cnc(C)n2nc(C[P+](c3ccccc3)(c3ccccc3)c3ccccc3)nc12.Cn1nc(Br)nc1C=O>>Cc1cnc(C)n2nc(/C=C/c3nc(Br)nn3C)nc12 -US06515011B2,6,CC(C)(C)OC(=O)NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@H](O)C1CCCCC1>>NCc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@H](O)C1CCCCC1 -US07888352B2,3,CS(=O)(=O)C1CCN(Cc2cc3c(N4CCOCC4)nc(Cl)nc3s2)CC1.Nc1ncc(B(O)O)cn1>>CS(=O)(=O)C1CCN(Cc2cc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3s2)CC1 -US08461134B2,2,NCc1cc(N)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2.O=S(=O)(Cl)C1CC1>>Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CNS(=O)(=O)C2CC2)c1 -US20090036474A1,1,CC(C)(C)OC(=O)N1CCC[C@H]1CO.O=[N+]([O-])c1ccc(Cl)c(O)c1>>CC(C)(C)OC(=O)N1CCC[C@H]1COc1cc([N+](=O)[O-])ccc1Cl -US06342610B2,3,Cc1cc(NS(=O)(=O)c2ccc(Br)cc2)on1.OB(O)c1ccc2c(c1)OCO2>>Cc1cc(NS(=O)(=O)c2ccc(-c3ccc4c(c3)OCO4)cc2)on1 -US06995263B2,7,CCOC(=O)c1cnc(-c2ccc(C(F)(F)F)nc2)nc1CCOC>>COCCc1nc(-c2ccc(C(F)(F)F)nc2)ncc1CO -US20090143385A1,2,CCOC(=O)c1ccc(NCc2c(-c3ccc(F)cc3)noc2C)nn1.NCC(F)(F)F>>Cc1onc(-c2ccc(F)cc2)c1CNc1ccc(C(=O)NCC(F)(F)F)nn1 -US03976771,9,CC(Br)C(=O)NC(C)(C)c1ccccc1.N>>C[C@H](N)C(=O)NC(C)(C)c1ccccc1 -US20050070549A1,1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.Clc1ccc(Br)cc1>>C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(Cl)cc1 -US20100113502A1,6,Cc1nc(Cn2c3c(c4cc(C(=O)N5CCC(C)CC5)ccc42)CN(C(=O)OC(C)(C)C)CC3)cs1>>Cc1nc(Cn2c3c(c4cc(C(=O)N5CCC(C)CC5)ccc42)CNCC3)cs1 -US20120220766A1,6,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)N3CCOCC3)c2C1)Cc1cc(F)c(F)cc1F>>N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)N3CCOCC3)c2C1)Cc1cc(F)c(F)cc1F -US06525064B1,2,CCCCc1nc2c(N)nc(C)c(C)c2n1CCCCN.CN(C)S(=O)(=O)Cl>>CCCCc1nc2c(N)nc(C)c(C)c2n1CCCCNS(=O)(=O)N(C)C -US08642538B2,6,CCOC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](Oc3nc4ccc(F)cc4c4cc(F)ccc34)C[C@H]1C(=O)N2>>CC(C)(C)OC(=O)N[C@H]1CCCCCC=C[C@@H]2C[C@@]2(C(=O)O)NC(=O)[C@@H]2C[C@@H](Oc3nc4ccc(F)cc4c4cc(F)ccc34)CN2C1=O -US20100041642A1,3,Brc1ccc(CN2CCOCC2)nc1.Cc1ccc(N)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(N)cc1-c1ccc(CN2CCOCC2)nc1 -US08476455B2,6,COc1ccc2c(CN(c3ccc(C#N)cc3)n3ccnc3)csc2c1>>N#Cc1ccc(N(Cc2csc3cc(O)ccc23)n2ccnc2)cc1 -US20030162795A1,3,Cc1cc2cc(Nc3ccnc4cc(Br)sc34)ccc2[nH]1.OB(O)c1ccoc1>>Cc1cc2cc(Nc3ccnc4cc(-c5ccoc5)sc34)ccc2[nH]1 -US07091219B2,6,COC(=O)[C@@H](C)CS(=O)(=O)N(Cc1ccccc1)C(c1ccccc1)c1ccccc1>>C[C@@H](CS(=O)(=O)N(Cc1ccccc1)C(c1ccccc1)c1ccccc1)C(=O)O -US20130281415A9,6,CC(C)(C)[Si](C)(C)OCCCCCCOCCOCc1ccccc1>>CC(C)(C)[Si](C)(C)OCCCCCCOCCO -US20060083947A1,3,Brc1c2ccccc2c(-c2ccc(C=Cc3ccccc3)cc2)c2ccccc12.OB(O)c1ccc(C=C(c2ccccc2)c2ccccc2)cc1>>C(=Cc1ccc(-c2c3ccccc3c(-c3ccc(C=C(c4ccccc4)c4ccccc4)cc3)c3ccccc23)cc1)c1ccccc1 -US20050203094A1,3,COC(=O)C(CO)(CO)c1cc(Br)c(OCc2ccccc2)c(C=O)c1.COCOc1ccc(F)cc1B(O)O>>COCOc1ccc(F)cc1-c1cc(C(CO)(CO)C(=O)OC)cc(C=O)c1OCc1ccccc1 -US20060122235A1,7,COC(=O)C1CC(=O)N(c2ccc(OCc3ccc(F)c(F)c3)cc2)C1>>O=C1CC(CO)CN1c1ccc(OCc2ccc(F)c(F)c2)cc1 -US20150087600A1,6,CCOC(=O)[C@@H]1CC[C@H](C)N1c1ncccn1>>C[C@H]1CC[C@@H](C(=O)O)N1c1ncccn1 -US20120245136A1,1,CC(C)(C)O.COc1cc(C(=O)N2CCC3(CC2)CC(O)c2ccccc2O3)ccc1OC(C)C>>COc1cc(C(=O)N2CCC3(CC2)CC(OC(C)(C)C)c2ccccc2O3)ccc1OC(C)C -US20110257171A1,6,CC(C)(C)OC(=O)N1CCC(n2cc(-c3ccc4ncc(Sc5ccc6nc(NC(=O)C7CC7)sc6c5)n4c3)cn2)CC1>>O=C(Nc1nc2ccc(Sc3cnc4ccc(-c5cnn(C6CCNCC6)c5)cn34)cc2s1)C1CC1 -US08163935B2,1,C1CCNC1.CCC(CC)c1ccc(C=O)c2nc(Oc3c(C)cc(Cl)cc3Cl)n(C)c12>>CCC(CC)c1ccc(CN2CCCC2)c2nc(Oc3c(C)cc(Cl)cc3Cl)n(C)c12 -US20100254916A1,2,CCOc1ccc(CNCc2ccco2)cc1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>CCOc1ccc(CN(Cc2ccco2)S(=O)(=O)c2ccc(C#N)cc2)cc1 -US20130203714A1,7,FC(F)(F)c1nnc2n1N=C(N1CC=C(c3c[nH]c4ccccc34)CC1)CC2>>FC(F)(F)c1nnc2n1N=C(N1CCC(c3c[nH]c4ccccc34)CC1)CC2 -US20110237584A1,6,CCOC(OCC)c1ccn(C)c(=O)c1>>Cn1ccc(C=O)cc1=O -US08334287B2,1,CI.Cc1nc(I)c(C)n1-c1cc[nH]c(=O)c1>>Cc1nc(I)c(C)n1-c1ccn(C)c(=O)c1 -US20090023753A1,2,CN=C=O.CNc1cc(CCl)ccn1>>CNC(=O)N(C)c1cc(CCl)ccn1 -US20060122064A1,3,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>CCOC(=O)C=Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1 -US20090008606A1,3,Brc1ccc(I)cc1.OB(O)c1ccc2ccccc2c1>>Brc1ccc(-c2ccc3ccccc3c2)cc1 -US07919502B2,2,Clc1cccc(N2CCNCC2)c1.O=C(O)c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1>>O=C(c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1)N1CCN(c2cccc(Cl)c2)CC1 -US07879850B2,7,COc1ccc(-c2nnc(-c3ccc(N)c([N+](=O)[O-])c3)o2)cc1>>COc1ccc(-c2nnc(-c3ccc(N)c(N)c3)o2)cc1 -US20140357858A1,2,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=C(Cl)c1ccccc1F>>O=C1CC(=O)N(c2ccc(NC(=O)c3ccccc3F)cc2)c2ccc3ccccc3c2N1 -US20080161289A1,1,CN1CCNC1=O.O=C(N1CCc2nc(-c3ccc(Cl)nc3)sc2CC1)C(F)(F)F>>CN1CCN(c2ccc(-c3nc4c(s3)CCN(C(=O)C(F)(F)F)CC4)cn2)C1=O -US20130053365A1,3,COC(=O)c1cc(F)cc(F)c1C(=O)Cc1ncnn1C.O=Cc1ccc(F)cc1>>COC(=O)c1cc(F)cc(F)c1C(=O)/C(=C/c1ccc(F)cc1)c1ncnn1C -US20040058903A1,2,Nc1ccc(CCc2ccccn2)nc1.O=C(Cl)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(CCc2ccccn2)nc1)c1ccccc1-c1ccc(C(F)(F)F)cc1 -US20080275029A1,3,CC(C)(C)OC(=O)N1CCC(C=O)(c2ccc(Cl)cc2)CC1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=CC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1 -US20110130415A1,1,CI.COC(=O)c1cc([N+](=O)[O-])cc(-n2nn[nH]c2=O)c1C>>COC(=O)c1cc([N+](=O)[O-])cc(-n2nnn(C)c2=O)c1C -US20080200431A1,2,COC(=O)[C@H]1CNCC(=O)N1CC1CCN(c2ccc(=O)n(C)n2)CC1.O=S(=O)(Cl)c1ccc2c(Cl)cn(S(=O)(=O)c3ccccc3)c2c1>>COC(=O)[C@H]1CN(S(=O)(=O)c2ccc3c(Cl)cn(S(=O)(=O)c4ccccc4)c3c2)CC(=O)N1CC1CCN(c2ccc(=O)n(C)n2)CC1 -US04270946,2,Nc1ccc(Cl)c(Cl)c1.O=C(Cl)c1cccnc1Oc1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c(Cl)c1)c1cccnc1Oc1cccc(C(F)(F)F)c1 -US20050143422A1,7,Cc1c(C(=O)O)oc2ccccc12>>Cc1c(CO)oc2ccccc12 -US20120101123A1,9,CCOC(=O)CCCn1ccc2c(Br)ccnc21.N#C[Cu]>>CCOC(=O)CCCn1ccc2c(C#N)ccnc21 -US08785647B2,7,O=C(O)c1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F>>OCc1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F -US20060004046A1,1,CCOC(=O)c1ccc2ncc(S(C)(=O)=O)c(Cl)c2c1.CC[O-]>>CCOC(=O)c1ccc2ncc(S(C)(=O)=O)c(OCC)c2c1 -US07041827B2,1,C1CCNCC1.Cc1cccn2cc(-c3ccc(NS(=O)(=O)CCCCl)cc3)nc12>>Cc1cccn2cc(-c3ccc(NS(=O)(=O)CCCN4CCCCC4)cc3)nc12 -US20140288066A1,3,CC1(C)OB(c2ccc(NC(=O)NC3CC3)cc2)OC1(C)C.C[C@H]1COCCN1c1nc(Cl)nc2c1SCCC2>>C[C@H]1COCCN1c1nc(-c2ccc(NC(=O)NC3CC3)cc2)nc2c1SCCC2 -US20150252047A1,2,CC(C)N.COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]cc(C(=O)O)c12>>COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]cc(C(=O)NC(C)C)c12 -US20090325930A1,3,CCCC[Sn](CCCC)(CCCC)c1cc2ccc(OC)cc2n1S(=O)(=O)c1ccccc1.COc1ccc(Br)c([N+](=O)[O-])c1>>COc1ccc(-c2cc3ccc(OC)cc3n2S(=O)(=O)c2ccccc2)c([N+](=O)[O-])c1 -US20060173018A1,1,CC(C)(C)OC(=O)NC1CCNCC1.Cc1ccc2c(Cl)nc(-c3ccccc3O)nc2c1>>Cc1ccc2c(N3CCC(NC(=O)OC(C)(C)C)CC3)nc(-c3ccccc3O)nc2c1 -US06300363B1,2,CC(=O)Cl.CCOC(=O)n1c(C(=O)c2cncnc2)c(N)c2ccc(Cl)cc21>>CCOC(=O)n1c(C(=O)c2cncnc2)c(NC(C)=O)c2ccc(Cl)cc21 -US20060264431A1,1,CNC.COC1=N[C@](CCBr)(CC2CC2)C(OC)=N[C@@H]1C(C)C>>COC1=N[C@](CCN(C)C)(CC2CC2)C(OC)=N[C@@H]1C(C)C -US20020028760A1,1,COc1ccc(F)cc1C1CCNCC1.O=C1CC2(CCCC2)CC(=O)N1CCCl>>COc1ccc(F)cc1C1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 -US06949542B2,2,CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1N.Cc1ncccc1-c1cccc(C(=O)CC(=O)OC(C)(C)C)c1>>Cc1ncccc1-c1cccc(C(=O)CC(=O)Nc2cc(C(F)(F)F)ccc2NC(=O)OC(C)(C)C)c1 -US08163793B2,6,COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C2CC2)n[nH]1>>O=C(O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C2CC2)n[nH]1 -US06410504B1,2,C=C(C)[C@H]1CC[C@@](C)(O)[C@H]1C.CC(=O)Cl>>C=C(C)[C@H]1CC[C@@](C)(OC(C)=O)[C@H]1C -US20040186060A1,9,N#Cc1csc(CBr)n1.[N-]=[N+]=[N-]>>N#Cc1csc(CN=[N+]=[N-])n1 -US08367831B2,1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCNCC1.O=CCn1c(=O)ccc2cccnc21>>CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3cccnc32)CC1 -US20040067960A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1ccccc1CCO>>Cc1ccc(S(=O)(=O)OCCc2ccccc2[N+](=O)[O-])cc1 -US20150239900A1,9,N.O=[N+]([O-])c1cccc(Br)c1F>>Nc1c(Br)cccc1[N+](=O)[O-] -US20090036420A1,2,Nc1ccc(Cl)c(Cl)c1.O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>O=C(Nc1ccc(Cl)c(Cl)c1)c1ccc(F)c([N+](=O)[O-])c1 -US05929067,6,CCOC(=O)CCC(Cc1c[nH]c2ccccc12)N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCC(=O)O)Cc1c[nH]c2ccccc12 -US20100080880A1,2,CC(C)=CCC/C(C)=C/CN.COC(=O)C(=O)O>>COC(=O)C(=O)NC/C=C(\C)CCC=C(C)C -US20080280911A1,6,CCOC(=O)c1c[nH]c2c(F)cc(I)cc2c1=O>>O=C(O)c1c[nH]c2c(F)cc(I)cc2c1=O -US06103718,1,COc1ccc(C2=NNC(=O)[C@H]3CCCC[C@@H]23)cc1OC.ClC(c1ccccc1)c1ccccc1>>COc1ccc(C2=NN(C(c3ccccc3)c3ccccc3)C(=O)[C@H]3CCCC[C@@H]23)cc1OC -US20090131461A1,6,COc1cc2c(Cl)ccnc2cc1OCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC1CCCC1>>COc1cc2c(Cl)ccnc2cc1OCC[C@H](N)C(=O)OC1CCCC1 -US07772253B2,1,CCOC(=O)C(C)(C)Oc1cccc(C(=O)NC2CCNCC2)c1.CCOc1cc(C=O)cc(OCC)c1F>>CCOC(=O)C(C)(C)Oc1cccc(C(=O)NC2CCN(Cc3cc(OCC)c(F)c(OCC)c3)CC2)c1 -US05972508,2,CCCCCCCC(=O)Cl.O=C1CCCCCN1>>CCCCCCCC(=O)N1CCCCCC1=O -US20130053404A1,3,CC(C)c1nc2c(c(I)c1[C@H](O)c1ccc(S(F)(F)(F)(F)F)cc1)[C@@H](O[Si](C)(C)C(C)(C)C)CC1(CCC1)C2.CC1(C)OB(C2=CCOCC2)OC1(C)C>>CC(C)c1nc2c(c(C3=CCOCC3)c1[C@H](O)c1ccc(S(F)(F)(F)(F)F)cc1)[C@@H](O[Si](C)(C)C(C)(C)C)CC1(CCC1)C2 -US05536816,2,CC(C)(C)OC(=O)n1cnc(C[C@H](NC(=O)[C@H](Cc2ccccc2)CS(=O)(=O)C(C)(C)C)C(=O)O)c1.N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1>>CC(C)(C)OC(=O)n1cnc(C[C@H](NC(=O)[C@H](Cc2ccccc2)CS(=O)(=O)C(C)(C)C)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)[C@@H](O)C2CC2)c1 -US07595314B2,1,C1CCNCC1.CNS(=O)(=O)c1ccc(Cl)c(C(=O)O)c1>>CNS(=O)(=O)c1ccc(N2CCCCC2)c(C(=O)O)c1 -US20080311113A1,1,CC1(C)OB(c2ccc(CBr)cc2)OC1(C)C.Cc1cc(O)c2ccccc2n1>>Cc1cc(OCc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c2ccccc2n1 -US20150073011A1,6,C=CCON1C(=O)N2C[C@H]1C(C)=C[C@H]2CO[Si](C)(C)C(C)(C)C>>C=CCON1C(=O)N2C[C@H]1C(C)=C[C@H]2CO -US20120114765A1,2,Cc1nc(N)sc1C.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>Cc1nc(NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)sc1C -US05541229,6,CCCCc1nc2cc(N(NC(=O)OC(C)(C)C)C(C)=O)ccc2n1Cc1ccc(-c2ccccc2C(=O)OCC)cc1>>CCCCc1nc2cc(N(NC(=O)OC(C)(C)C)C(C)=O)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 -US04556711,7,O=C(Nc1ccc(-c2c[nH]c(=O)cn2)cc1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(C(=O)Nc2ccc(-c3c[nH]c(=O)cn3)cc2)c1 -US05071875,2,CC(C)C(=O)Cl.COc1cccc2c1CC(N)CC2>>COc1cccc2c1CC(NC(=O)C(C)C)CC2 -US07622479B2,4,COc1cccc(C(=O)O)c1.Nc1cc(Br)cnc1N>>COc1cccc(-c2nc3ncc(Br)cc3[nH]2)c1 -US20060264460A1,1,Cc1cc(C=O)oc1C.N#Cc1cnc2c(C(F)(F)F)cc(N)cc2c1Nc1ccc(F)c(Cl)c1>>Cc1cc(CNc2cc(C(F)(F)F)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)oc1C -US20140113931A1,1,CC(C)[C@@H](Nc1cnc(C#N)c(Br)c1)C(N)=O.Cc1cc(N)sn1>>Cc1cc(Nc2cc(N[C@@H](C(N)=O)C(C)C)cnc2C#N)sn1 -US20040063720A1,1,COCCN1CCNCC1.Nc1cc(Cl)ncn1>>COCCN1CCN(c2cc(N)ncn2)CC1 -US06307056B1,7,COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(-c3ccc4cc[nH]c4c3)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(N)c(-c3ccc4cc[nH]c4c3)c21 -US20060178416A1,1,COc1cccc(N)c1.Cc1c(Cl)ccc2c(Cl)c(C(N)=O)cnc12>>COc1cccc(Nc2c(C(N)=O)cnc3c(C)c(Cl)ccc23)c1 -US07781438B2,10,COC(=O)Cc1c(Cl)ccc2ncc(C)cc12.O=C1CCC(=O)N1Br>>COC(=O)Cc1c(Cl)ccc2ncc(CBr)cc12 -US07235547B2,3,C=CB(O)O.CC(C)(C)OC(=O)Nc1cc(Cl)c(C(F)(F)F)cc1[N+](=O)[O-]>>C=Cc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C(F)(F)F -US08716296B2,6,COc1ccccc1-c1cc(NC(=O)C2CCCN(C(=O)OCc3ccccc3)C2)ncn1>>COc1ccccc1-c1cc(NC(=O)C2CCCNC2)ncn1 -US20080119488A1,2,Cc1ccc(CN)c(C)c1.N#CCC(=O)O>>Cc1ccc(CNC(=O)CC#N)c(C)c1 -US20090233937A1,2,CC(C)(C)C(=O)OC(=O)C(C)(C)C.Cc1cc(Nc2ncnc3ccn(CCN)c23)ccc1Oc1cccc2sncc12>>Cc1cc(Nc2ncnc3ccn(CCNC(=O)C(C)(C)C)c23)ccc1Oc1cccc2sncc12 -US08901156B2,1,CC(C)(CN)c1coc(-c2ccc(Cl)cc2)n1.O=Cc1cccc(-c2noc(C(F)(F)F)n2)c1>>CC(C)(CNCc1cccc(-c2noc(C(F)(F)F)n2)c1)c1coc(-c2ccc(Cl)cc2)n1 -US08901156B2,1,CC(C)(CN)c1coc(-c2ccc(Cl)cc2)n1.O=Cc1cccc(-c2noc(C(F)(F)F)n2)c1>>CC(C)(CNCc1cccc(-c2noc(C(F)(F)F)n2)c1)c1coc(-c2ccc(Cl)cc2)n1 -US20080056987A1,1,CCOC(=O)c1cnc2ccc3c(c2c1Cl)CCS3(=O)=O.NCc1ccccc1>>CCOC(=O)c1cnc2ccc3c(c2c1NCc1ccccc1)CCS3(=O)=O -US20080085886A1,1,CCOC(=O)c1oc2c(Br)cncc2c1OS(=O)(=O)C(F)(F)F.C[Si](C)(C)c1ccc(N)c(F)c1>>CCOC(=O)c1oc2c(Br)cncc2c1Nc1ccc([Si](C)(C)C)cc1F -US05387684,6,CCCCc1nc(Cl)c(C=O)n1Cc1ccc2nn(-c3ccccc3C(=O)OCC)c(Br)c2c1>>CCCCc1nc(Cl)c(C=O)n1Cc1ccc2nn(-c3ccccc3C(=O)O)c(Br)c2c1 -US20070249674A1,1,CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c(NC=O)c1.Cc1cc(NC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(C)cc1C=O>>Cc1cc(NC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(C)cc1CNC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c(NC=O)c1 -US20050004204A1,6,CCOc1cc(CN(CC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC(C)(C)C)c(Br)cc1C(=O)NC>>CCOc1cc(CNCC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c(Br)cc1C(=O)NC -US08183262B2,1,CCCC[Sn](Cl)(CCCC)CCCC.Fc1ccc(-c2cc(C(F)(F)F)nc(-n3cnc(I)c3)n2)cc1>>CCCC[Sn](CCCC)(CCCC)c1cn(-c2nc(-c3ccc(F)cc3)cc(C(F)(F)F)n2)cn1 -US20150141400A1,7,CCSc1ccccc1C#N>>CCSc1ccccc1CN -US20080004300A1,1,CN1CCC(N)CC1.COc1ccc(N2C(=O)N(Cc3ccnc4ccccc34)C(C)(C)C2=O)cc1OCC=O>>COc1ccc(N2C(=O)N(Cc3ccnc4ccccc34)C(C)(C)C2=O)cc1OCCNC1CCN(C)CC1 -US05262436,6,CC(=O)SCC(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O>>C[C@H](NC(=O)C(CS)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O -US04737185,2,COC(=O)c1cccc(S(=O)(=O)N(C)C)c1CS(=O)(=O)N=C=O.COc1cc(OC)nc(N)n1>>COC(=O)c1cccc(S(=O)(=O)N(C)C)c1CS(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1 -US20120316147A1,2,CC(C)C[C@H](N)C(N)=O.O=C(O)c1ccc(NC2CC2)c(OCC2CC2)n1>>CC(C)C[C@H](NC(=O)c1ccc(NC2CC2)c(OCC2CC2)n1)C(N)=O -US04328241,7,CSCC(=O)Nc1cc(SCC(C)C)ccc1[N+](=O)[O-]>>CSCC(=O)Nc1cc(SCC(C)C)ccc1N -US20140329812A1,4,C#Cc1ccc(CO)cc1.CC(C)c1cc(N=[N+]=[N-])c(OCc2ccccc2)cc1OCc1ccccc1>>CC(C)c1cc(-n2nncc2-c2ccc(CO)cc2)c(OCc2ccccc2)cc1OCc1ccccc1 -US07273877B2,1,CCOC(=O)c1c[nH]c(=O)cc1Nc1ccc(I)cc1F.N#CCCCBr>>CCOC(=O)c1cn(CCCC#N)c(=O)cc1Nc1ccc(I)cc1F -US08158617B2,6,Clc1nccc2c1OCCN(Cc1ccccc1)C2>>Clc1nccc2c1OCCNC2 -US08937073B2,2,COc1ccc(Nc2cnc(CN)c(Cl)c2)c(C(F)(F)F)c1.Nc1cncc(C(=O)N[C@@]2(C(=O)O)CCOC2)c1>>COc1ccc(Nc2cnc(CNC(=O)[C@]3(NC(=O)c4cncc(N)c4)CCOC3)c(Cl)c2)c(C(F)(F)F)c1 -US06593333B1,1,COc1cc2c(Cl)ncnc2cc1OCC1CCCN(C)C1.Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1N>>COc1cc2c(Nc3cc(NC(=O)c4ccnc(N5CCOCC5)c4)ccc3C)ncnc2cc1OCC1CCCN(C)C1 -US05981533,7,CN(C)C=Nc1[nH]nc(-c2ccc([N+](=O)[O-])cc2)c1C#N>>CN(C)C=Nc1[nH]nc(-c2ccc(N)cc2)c1C#N -US20140213448A1,2,CCN(C(=O)CCNCCC(F)(F)F)c1cn(-c2cccnc2)nc1Cl.CS(=O)(=O)Cl>>CCN(C(=O)CCN(CCC(F)(F)F)S(C)(=O)=O)c1cn(-c2cccnc2)nc1Cl -US07482448B2,2,COC(=O)[C@@H](N)CC(F)(F)Cc1ccccc1.O=C(Cl)N1CCOCC1>>COC(=O)[C@H](CC(F)(F)Cc1ccccc1)NC(=O)N1CCOCC1 -US20080076771A1,2,COC(=O)c1ccc(Nc2cc(Cl)ncn2)cc1.Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1>>O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2cc(Cl)ncn2)cc1 -US07030063B1,6,COC(=O)c1ccc(OC(F)F)c2ncccc12>>O=C(O)c1ccc(OC(F)F)c2ncccc12 -US08436023B2,1,CCC1CCC(=O)CC1.O=C(CNc1noc2ccc(C(F)(F)F)cc12)NC1CNC1>>CCC1CCC(N2CC(NC(=O)CNc3noc4ccc(C(F)(F)F)cc34)C2)CC1 -US20090239899A1,9,Clc1ccc(Br)cn1.NN>>NNc1ccc(Br)cn1 -US20110313151A1,2,CO[C@H](C)C(=O)O.N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1>>CO[C@H](C)C(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1 -US20060211678A1,6,CC(C)(CN1CCCCC1)C(=O)OCc1ccccc1>>CC(C)(CN1CCCCC1)C(=O)O -US20120277220A1,6,CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc3OC)nc21>>CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc(C4CCNCC4)cc3OC)nc21 -US20040209886A1,1,CCOC(=O)c1cn2ncc(C#N)c(Cl)c2c1OC.Nc1ccc(Oc2ccccc2)cc1>>CCOC(=O)c1cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c2c1OC -US08541580B2,3,Brc1ccccn1.CCOC(=O)C(F)(F)Br>>CCOC(=O)C(F)(F)c1ccccn1 -US07179823B1,6,CCOC(=O)CCc1cn(Cc2cccc(OCc3nc(-c4ccccc4)oc3C)c2)nc1OCC>>CCOc1nn(Cc2cccc(OCc3nc(-c4ccccc4)oc3C)c2)cc1CCC(=O)O -US04638000,7,CCOC(=O)C=CC1CCSCC1>>CCOC(=O)CCC1CCSCC1 -US20150175628A1,2,CC(=O)NCC(=O)O.NNC(=O)c1ccc([N+](=O)[O-])cn1>>CC(=O)NCC(=O)NNC(=O)c1ccc([N+](=O)[O-])cn1 -US20130296298A1,1,CCC(Br)C(=O)N1CCCCC1.Fc1ccccc1-c1nnc2ccc(S)nn12>>CCC(Sc1ccc2nnc(-c3ccccc3F)n2n1)C(=O)N1CCCCC1 -US05650410,1,CCC(C)N.COc1ccc(-c2nc(CCl)nc3cc(OC)c(OC)cc23)cc1OC>>CCC(C)NCc1nc(-c2ccc(OC)c(OC)c2)c2cc(OC)c(OC)cc2n1 -US20140322355A1,9,CCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C(N)=O)cc4)CC3)c(CC)cc2CC)[nH]1>>CCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(CC)cc2CC)[nH]1 -US20140038975A1,7,CCOC(=O)[C@@](C)(CCn1cc(C2=CCCC2)cn1)S(C)(=O)=O>>CCOC(=O)[C@@](C)(CCn1cc(C2CCCC2)cn1)S(C)(=O)=O -US08338605B2,1,CC(=O)Nc1ccc(COc2cc(N)cc(Cl)c2)cc1.Cc1ccc2c(Cl)ccnc2n1>>CC(=O)Nc1ccc(COc2cc(Cl)cc(Nc3ccnc4nc(C)ccc34)c2)cc1 -US05665737,7,O=[N+]([O-])c1cccc([N+](=O)[O-])c1O>>Nc1cccc([N+](=O)[O-])c1O -US20120214784A1,1,C1COCCN1.CCOC(=O)c1cn(-c2c(F)cccc2C=O)nc1C>>CCOC(=O)c1cn(-c2c(F)cccc2CN2CCOCC2)nc1C -US20060287356A1,1,CC=O.N#Cc1c(O)c2c(-c3ccc(OCC4(O)CCNCC4)cc3)c(Cl)sc2[nH]c1=O>>CCN1CCC(O)(COc2ccc(-c3c(Cl)sc4[nH]c(=O)c(C#N)c(O)c34)cc2)CC1 -US04344948,1,O=C(CBr)c1ccc(Cl)cc1.O=C1Nc2ccccc2CN1C1CCNCC1>>O=C(CN1CCC(N2Cc3ccccc3NC2=O)CC1)c1ccc(Cl)cc1 -US06884868B1,1,BrCCCCBr.CC(C)(C)OC(=O)N1CCC(O)CC1>>CC(C)(C)OC(=O)N1CCC(OCCCCBr)CC1 -US20130184313A1,9,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc(CCc2cccc(CCl)c2)c1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc(CCc2cccc(CN=[N+]=[N-])c2)c1 -US05914328,1,C=O.Cc1ccncc1OC[C@@H]1CCCN1>>Cc1ccncc1OC[C@@H]1CCCN1C -US07435744B2,2,Nc1ccc2c(c1)CC(=O)N2.O=C(O)C(=O)N1CCC(Cc2ccccc2)CC1>>O=C1Cc2cc(NC(=O)C(=O)N3CCC(Cc4ccccc4)CC3)ccc2N1 -US20070015802A1,7,COc1cc(OC)c2c(=O)cc(-c3ccc([N+](=O)[O-])cc3Br)oc2c1[C@@H]1CCN(C)[C@H]1CO>>COc1cc(OC)c2c(=O)cc(-c3ccc(N)cc3Br)oc2c1[C@@H]1CCN(C)[C@H]1CO -US20130291227A1,2,CC(CSC(F)(F)F)C(=O)O.CNc1cn(-c2cccnc2)nc1Cl>>CC(CSC(F)(F)F)C(=O)N(C)c1cn(-c2cccnc2)nc1Cl -US04889553,2,CCCC(=O)OC(=O)CCC.NC(=S)NNc1ccccc1>>CCCC(=O)N(NC(N)=S)c1ccccc1 -US20060287343A1,3,C#C[Si](C)(C)C.COC(=O)Cc1ccc(F)cc1I>>COC(=O)Cc1ccc(F)cc1C#C[Si](C)(C)C -US05834461,2,O=C(O)c1ccc([N+](=O)[O-])cc1Cl.c1ccc2c(c1)CCCCN2>>O=C(c1ccc([N+](=O)[O-])cc1Cl)N1CCCCc2ccccc21 -US20090163489A1,3,CC(=O)Nc1nc2ccc(-c3cnc(Cl)c(NS(=O)(=O)c4cccc(OC(F)F)c4)c3)nn2c1I.OB(O)c1ccncc1>>CC(=O)Nc1nc2ccc(-c3cnc(Cl)c(NS(=O)(=O)c4cccc(OC(F)F)c4)c3)nn2c1-c1ccncc1 -US20080261941A1,1,FC(F)(F)c1ccc(Cl)nc1.Oc1cc(F)cc(Br)c1>>Fc1cc(Br)cc(Oc2ccc(C(F)(F)F)cn2)c1 -US20150225394A1,6,CC(C)(C)OC(=O)N1CC(CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)C1>>O=C(N(CC1CNC1)[C@@H]1C[C@H]1c1ccccc1)C(F)(F)F -US20120270875A1,6,COC(=O)[C@H](CNC(=O)c1cccs1)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C>>Cc1nc(NCCCc2cccc(O)c2)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O -US07071221B2,6,COC(=O)C(Cc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1)NC(=O)OC(C)(C)C>>COC(=O)C(N)Cc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1 -US04645854,7,COC(=O)CC(=O)CC(O)/C=C/c1c(C)cc(C)cc1-c1ccc(F)c(C)c1>>COC(=O)CC(O)CC(O)/C=C/c1c(C)cc(C)cc1-c1ccc(F)c(C)c1 -US06995143B2,1,ClCCCBr.Ic1cn[nH]c1>>ClCCCn1cc(I)cn1 -US20080139390A1,9,BrC(Br)(Br)Br.Cc1nsc(C#N)c1CO>>Cc1nsc(C#N)c1CBr -US20110190269A1,1,COc1cc(Br)ccc1-n1cnc(C)c1.Nc1nc2cccc(N3CCOCC3)n2n1>>COc1cc(Nc2nc3cccc(N4CCOCC4)n3n2)ccc1-n1cnc(C)c1 -US03997568,1,C=[N+]=[N-].C[C@H](O)CCC1OCCOC1CCC/C=C/c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1C(=O)O>>COC(=O)c1c(/C=C/CCCC2OCCOC2CC[C@H](C)O)cc(OCc2ccccc2)cc1OCc1ccccc1 -US04435419,7,O=C(c1ccc(F)cc1)N1CC2CC2(c2ccccc2)C1>>Fc1ccc(CN2CC3CC3(c3ccccc3)C2)cc1 -US08513239B2,2,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)O)CC1.CO[C@H]1CCNC1>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N2CC[C@H](OC)C2)CC1 -US04598148,1,CI.COc1cc2c(cc1OC)-c1cc(=O)[nH]c(=O)n1CC2>>COc1cc2c(cc1OC)-c1cc(=O)n(C)c(=O)n1CC2 -US06489354B1,8,OCC1CN(Cc2ccccc2)CC1C(F)(F)F>>O=CC1CN(Cc2ccccc2)CC1C(F)(F)F -US20120122895A1,6,COc1ccc(Cl)cc1NC(=O)Nc1cccc2c1CCN2Cc1ccnc2c1ccn2C(=O)OC(C)(C)C>>COc1ccc(Cl)cc1NC(=O)Nc1cccc2c1CCN2Cc1ccnc2[nH]ccc12 -US05073565,2,CC(C)c1cccc(C(C)C)c1N=C=O.CCCCCCCCCCCCn1nnnc1N>>CCCCCCCCCCCCn1nnnc1NC(=O)Nc1c(C(C)C)cccc1C(C)C -US09139581B2,1,CC(=O)N1CCN(c2ccc(N)cc2)CC1.Cc1ccc(S(=O)(=O)n2ccc3c(N[C@H](C)CO)nc(Cl)nc32)cc1>>CC(=O)N1CCN(c2ccc(Nc3nc(N[C@H](C)CO)c4ccn(S(=O)(=O)c5ccc(C)cc5)c4n3)cc2)CC1 -US06046206,2,CS(=O)(=O)Cl.Nc1cc(CNc2ncnc3ccc(Cl)cc23)ccc1Cl>>CS(=O)(=O)Nc1cc(CNc2ncnc3ccc(Cl)cc23)ccc1Cl -US20100174065A1,6,CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCN(C(=O)OC(C)(C)C)C4)no2)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCNC4)no2)cc1Cl -US08497294B2,4,C[S+](C)C.O=C(c1ccc(Cl)cc1)c1ccc(I)cc1>>Clc1ccc(C2(c3ccc(I)cc3)CO2)cc1 -US20120208797A1,1,Cn1c(Cl)nc(-c2ccncc2F)cc1=O.OC[C@H]1CCN(c2ccsc2)C1>>Cn1c(OC[C@H]2CCN(c3ccsc3)C2)nc(-c2ccncc2F)cc1=O -US05206240,6,CCOC(=O)C1(Cc2ccccc2)CCN(C(=O)c2ccccc2)CC1>>O=C(c1ccccc1)N1CCC(Cc2ccccc2)(C(=O)O)CC1 -US20110263571A1,1,Cc1cc(F)ncc1C(=O)N1CCN(c2ccc(C3CC3)cc2C2CC2)CC1.O=C1NCCO1>>Cc1cc(N2CCOC2=O)ncc1C(=O)N1CCN(c2ccc(C3CC3)cc2C2CC2)CC1 -US20120316147A1,2,NC(=O)[C@@H](N)CC1CC1.O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1>>NC(=O)[C@H](CC1CC1)NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 -US07001895B2,3,CC(C)COc1c(Br)cnn(-c2cccc(Cl)c2)c1=O.CSc1ccc(B(O)O)cc1F>>CSc1ccc(-c2cnn(-c3cccc(Cl)c3)c(=O)c2OCC(C)C)cc1F -US20140171430A1,2,Cc1cc(C)nc(N2CC3CNCC3C2)n1.Cc1noc(-c2cccc(F)c2C(=O)O)n1>>Cc1cc(C)nc(N2CC3CN(C(=O)c4c(F)cccc4-c4nc(C)no4)CC3C2)n1 -US04182775,9,Cc1ccc(CNC(=O)c2cc(Cl)ccc2Cl)cc1C(=O)O>>Cc1ccc(CNC(=O)c2cccc(Cl)c2)cc1C(=O)O -US20130029991A1,2,CC(=O)Nc1ccc(N)cn1.O=C(O)CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1>>CC(=O)Nc1ccc(NC(=O)CNC(=O)c2ccc(S(=O)(=O)Nc3ccccc3Oc3ccccc3)cc2)cn1 -US06252084B1,1,CCOC(=O)CCCBr.Cc1c(CC(N)=O)c2ccc(O)cc2n1Cc1ccccc1>>CCOC(=O)CCCOc1ccc2c(CC(N)=O)c(C)n(Cc3ccccc3)c2c1 -US20090221555A1,7,COCCN1C(=O)CCCc2cc([N+](=O)[O-])ccc21>>COCCN1C(=O)CCCc2cc(N)ccc21 -US06191282B1,9,N#C[Cu].O=C(c1ccc(Br)cc1)C1CC1>>N#Cc1ccc(C(=O)C2CC2)cc1 -US04549988,3,C#CCO.Clc1ccc2c(c1)C(c1ccccc1)=NCC=C2Br>>OCC#CC1=CCN=C(c2ccccc2)c2cc(Cl)ccc21 -US07521461B2,6,COC(=O)c1ccccc1COc1ccc(CCC(=O)N(C)CCc2ccc(OC)c(OC)c2)cc1>>COc1ccc(CCN(C)C(=O)CCc2ccc(OCc3ccccc3C(=O)O)cc2)cc1OC -US20120108606A1,2,NC1CCN(Cc2ccccc2)CC1.O=C(O)c1cc2cc(O)ccc2[nH]1>>O=C(NC1CCN(Cc2ccccc2)CC1)c1cc2cc(O)ccc2[nH]1 -US20080261987A1,2,Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)O.c1ccc(N2CCNCC2)nc1>>Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccccn2)CC1 -US20150005279A1,6,Cc1ccccc1C(=O)N[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>Cc1ccccc1C(=O)N[C@@H]1CCCNC1 -US20100113502A1,6,CSc1ccc(Cn2c3c(c4cc(C(=O)N5CCC(C)CC5)ccc42)CN(C(=O)OC(C)(C)C)CC3)cc1>>CSc1ccc(Cn2c3c(c4cc(C(=O)N5CCC(C)CC5)ccc42)CNCC3)cc1 -US20150175557A1,7,CC1(C)C(=O)CCCC1=O>>CC1(C)C(=O)CCCC1O -US20120270875A1,6,COC(=O)[C@H](CNC(=O)c1cnccn1)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C>>Cc1nc(NCCCc2cccc(O)c2)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cnccn1)C(=O)O -US04018922,6,CCOC(=O)COC1CCN(Cc2ccccc2)CC1>>CCOC(=O)COC1CCNCC1 -US20020013328A1,1,C1CNCCN1.CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(NC(=O)CCl)cc3)nc(=O)c1-2>>CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(NC(=O)CN4CCNCC4)cc3)nc(=O)c1-2 -US20100298221A1,9,Oc1cc(Br)ccc1Cl.[C-]#N>>N#Cc1ccc(Cl)c(O)c1 -US04812565,1,CNC.O=C1c2cccnc2OC(CCl)CN1C1CCCCC1>>CN(C)CC1CN(C2CCCCC2)C(=O)c2cccnc2O1 -US20060084643A1,1,N#Cc1cc(C(F)(F)F)ccc1F.Nc1ccc(Cl)cc1[N+](=O)[O-]>>N#Cc1cc(C(F)(F)F)ccc1Nc1ccc(Cl)cc1[N+](=O)[O-] -US20030087952A1,2,CCOC(=O)CNC.O=C(O)C#Cc1ccccc1F>>CCOC(=O)CN(C)C(=O)C#Cc1ccccc1F -US08106091B2,3,Brc1ccc(I)cc1.C#CC[C@H](NC(=O)OC(C)(C)C)C(=O)OC1CCCC1>>CC(C)(C)OC(=O)N[C@@H](CC#Cc1ccc(Br)cc1)C(=O)OC1CCCC1 -US20120316147A1,2,Cc1nc(C(C)(N)C2CC2)no1.O=C(O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1>>Cc1nc(C(C)(NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)C2CC2)no1 -US08933105B2,2,CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.Cc1occc1S(=O)(=O)Cl>>Cc1occc1S(=O)(=O)n1cc(CN(C)C(=O)OC(C)(C)C)c(F)c1-c1cccnc1F -US04348527,2,CC1CC(N)=NN1c1ccccc1.CCC(=O)OC(=O)CC>>CCC(=O)NC1=NN(c2ccccc2)C(C)C1 -US20140142074A1,6,O=C(COC(=O)c1ccc(OCC2CC2)c(CN2CCOCC2)c1)OCc1ccccc1>>O=C(O)COC(=O)c1ccc(OCC2CC2)c(CN2CCOCC2)c1 -US06258829B1,6,CCOC(=O)c1cc2c(nc1C)CCCCC2>>Cc1nc2c(cc1C(=O)O)CCCCC2 -US07101898B2,1,C1=COCCC1.Oc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(OC2CCCCO2)cc1 -US20050113397A1,7,CCOC(=O)c1cccc([N+](=O)[O-])c1N>>CCOC(=O)c1cccc(N)c1N -US20070093535A1,7,COC(=O)c1ccc(/C=C/c2cc(SC)ccc2OC(C)=O)nc1>>COC(=O)c1ccc(/C=C/c2cc(SC)ccc2O)nc1 -US20050101586A1,1,O=C(CBr)c1ccc(F)cc1.O=S(=O)(CC1CNC1)c1ccc(F)cc1F>>O=C(CN1CC(CS(=O)(=O)c2ccc(F)cc2F)C1)c1ccc(F)cc1 -US20090131431A1,2,CCn1ncc2c(NC3CCOCC3)c(CN)c(C)nc21.Cc1ncc(C(=O)O)cn1>>CCn1ncc2c(NC3CCOCC3)c(CNC(=O)c3cnc(C)nc3)c(C)nc21 -US07803822B2,6,CCNC(=O)c1ccc(-n2cc(C(=O)OCC)nn2)c(OCCCc2ccccc2)c1>>CCNC(=O)c1ccc(-n2cc(C(=O)O)nn2)c(OCCCc2ccccc2)c1 -US20080096861A1,1,CC(C)(C)OC(=O)N1CCC[C@H](Cn2c(CCl)nc3ccccc32)C1.OCCCN[C@H]1CCCc2cccnc21>>CC(C)(C)OC(=O)N1CCC[C@H](Cn2c(CN(CCCO)[C@H]3CCCc4cccnc43)nc3ccccc32)C1 -US05371081,1,CCNCC.ClCCCN1c2ccccc2Oc2ccccc21>>CCN(CC)CCCN1c2ccccc2Oc2ccccc21 -US20090281152A1,6,COC(=O)c1cn(CC(C)C)c2ccc(C)cc12>>Cc1ccc2c(c1)c(C(=O)O)cn2CC(C)C -US20130158112A1,2,NCCSCc1cccc(F)c1.O=C(Cl)c1c(F)cccc1F>>O=C(NCCSCc1cccc(F)c1)c1c(F)cccc1F -US20150045378A1,7,COC(=O)c1cc(OCC(C)C)c(-c2cc(OC)ccc2F)nc1OC>>COc1ccc(F)c(-c2nc(OC)c(CO)cc2OCC(C)C)c1 -US20040014745A1,2,CC(=O)N1CCC(N)CC1.O=C(Cl)c1ccc(F)cc1>>CC(=O)N1CCC(NC(=O)c2ccc(F)cc2)CC1 -US20040110762A1,1,N#Cc1cnc2cc3ccccc3cc2c1Cl.Nc1ccc(F)c(Cl)c1>>N#Cc1cnc2cc3ccccc3cc2c1Nc1ccc(F)c(Cl)c1 -US20140107109A1,1,COc1cnc2c(N)nccc2c1.C[C@@]1(c2cc(Br)ccc2F)CS(=O)(=O)C2(CC2)C(N)=N1>>COc1cnc2c(Nc3ccc(F)c([C@]4(C)CS(=O)(=O)C5(CC5)C(N)=N4)c3)nccc2c1 -US20090036492A1,1,CCCOc1c(C)c(C)c(C=O)c2ccccc12.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCCOc1c(C)c(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c2ccccc12 -US06166030,7,CN1CCc2ccc([N+](=O)[O-])cc2C1>>CN1CCc2ccc(N)cc2C1 -US20110172216A1,1,CS(=O)(=O)N1CCNCC1.Cn1ncc2c(Cl)nc(Cl)nc21>>Cn1ncc2c(N3CCN(S(C)(=O)=O)CC3)nc(Cl)nc21 -US20070155805A1,3,CCCCC(=O)c1sc2cc(OC)ccc2c1C.CCOC(=O)CP(=O)(OCC)OCC>>CCCCC(=CC(=O)OCC)c1sc2cc(OC)ccc2c1C -US20130053373A1,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1=N[C@@]2(c3ccccc3F)CO[C@@H](CO)C[C@H]2CS1>>CC(C)(C)OC(=O)NC1=N[C@@]2(c3ccccc3F)CO[C@@H](CO)C[C@H]2CS1 -US20030078251A1,2,COC(=O)[C@@H](C)N.COc1cccc([C@H]2O[C@H](CC(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COC(=O)[C@@H](C)NC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2N(CC(C)(C)CO)C1=O -US20070213348A1,5,COCCl.Oc1ccc(Br)cc1>>COCOc1ccc(Br)cc1 -US04254134,4,CC(=O)NC1CCCC(=O)C1.NNc1ccc(Br)cc1>>CC(=O)NC1CCc2c([nH]c3ccc(Br)cc23)C1 -US08440666B2,6,CCC(c1ccncn1)N1C(=O)c2ccccc2C1=O>>CCC(N)c1ccncn1 -US04283556,1,CCO.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>CCOc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] -US08946481B2,7,C/C(=C\[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)O>>C[C@@H](C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)O -US20130184273A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4nccn4cc3-c3ccccc3)cc2)CCC1>>NC1(c2ccc(-c3nc4nccn4cc3-c3ccccc3)cc2)CCC1 -US20150232429A1,3,FC(F)(F)c1ccnc(Cl)c1.Fc1cc(-c2ccnc(Nc3ccc(-n4cnc(Br)n4)cc3)n2)cc(N2CCOCC2)c1>>Fc1cc(-c2ccnc(Nc3ccc(-n4cnc(-c5cc(C(F)(F)F)ccn5)n4)cc3)n2)cc(N2CCOCC2)c1 -US20140315881A1,2,Cc1cc(Cl)ccc1C(N)c1ccccc1.O=C(O)Cc1ccc2oc(-c3cccnc3CO)cc2c1>>Cc1cc(Cl)ccc1C(NC(=O)Cc1ccc2oc(-c3cccnc3CO)cc2c1)c1ccccc1 -US09156827B2,6,COc1cc(CN2CCN(C(=O)OC(C)(C)C)CC2)c2c(c1)C(=O)/C(=C/c1c[nH]c3ccccc13)O2>>COc1cc(CN2CCNCC2)c2c(c1)C(=O)/C(=C/c1c[nH]c3ccccc13)O2 -US20050222419A1,2,NNc1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(Cl)CCl>>O=C(CCl)NNc1c(Cl)cc(C(F)(F)F)cc1Cl -US05616712,3,C#Cc1ccc2c(c1)N(C(C)C)C(=O)CC2(C)C.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(C#Cc2ccc3c(c2)N(C(C)C)C(=O)CC3(C)C)cc1 -US20150238597A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCCCCO>>Cc1ccc(S(=O)(=O)OCCCCCCO)cc1 -US07622479B2,4,Nc1cc(Br)cnc1N.O=C(O)c1cccc(Cl)c1>>Clc1cccc(-c2nc3ncc(Br)cc3[nH]2)c1 -US20060167044A1,3,CC(C)(C)OC(=O)N1CCC(=O)CC1.Fc1ccc(C[Mg+])cc1>>CC(C)(C)OC(=O)N1CCC(O)(Cc2ccc(F)cc2)CC1 -US20120270874A1,1,OCCN1CCOCC1.Oc1ccc(Br)c(F)c1>>Fc1cc(OCCN2CCOCC2)ccc1Br -US20080004321A1,7,COC(=O)c1ccc(F)c([N+](=O)[O-])c1>>COC(=O)c1ccc(F)c(N)c1 -US20140058098A1,6,CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(C3CN(C(=O)OC(C)(C)C)C3)cc1OCC2>>CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(C3CNC3)cc1OCC2 -US08362044B2,6,CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=NCc2ccccc2)NC#N)c1>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=NCc1ccccc1)NC#N -US05753664,1,Cc1cc2c([nH]1)c(=O)n(C)c(=O)n2C.O=C(c1ccc(Cl)cc1)c1ccc(CBr)cc1>>Cc1cc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1 -US07943636B2,9,COCCn1nc(C(N)=O)cc1CC1CCOCC1>>COCCn1nc(C#N)cc1CC1CCOCC1 -US04152329,2,CC(C)C(=O)Cl.CNc1nc(CC(=O)Nc2cccc(C(F)(F)F)c2)cs1>>CC(C)C(=O)N(C)c1nc(CC(=O)Nc2cccc(C(F)(F)F)c2)cs1 -US20060287363A1,2,CC(=O)Cl.Nc1cccc(N)n1>>CC(=O)Nc1cccc(N)n1 -US06423704B1,2,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.CS(=O)(=O)c1ccc(-n2cnnn2)cc1C(=O)O>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(-n5cnnn5)ccc4S(C)(=O)=O)C3)CC2)nc2ccccc21 -US07378417B2,2,Nc1cccc(S(N)(=O)=O)c1.O=C(O)c1cnn2c(C(F)F)cc(-c3ccc(C(F)(F)F)c(F)c3)nc12>>NS(=O)(=O)c1cccc(NC(=O)c2cnn3c(C(F)F)cc(-c4ccc(C(F)(F)F)c(F)c4)nc23)c1 -US20050148624A1,3,CCCC(=O)CN(Cc1ccc(S(C)(=O)=O)cc1)C(=O)c1ccc(Br)cc1C(=O)c1ccccc1>>CCCC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(C)(=O)=O)cc1 -US20130225552A1,1,CC(C)(C)OC(=O)N[C@H]1C[C@H](O)C1.Cn1c(Cl)nc2ccccc21>>Cn1c(O[C@@H]2C[C@@H](NC(=O)OC(C)(C)C)C2)nc2ccccc21 -US20150166595A1,7,O=[N+]([O-])c1ccc(CN2CCOCC2)cc1>>Nc1ccc(CN2CCOCC2)cc1 -US04537967,2,CC(=O)CCC(=S)Cl.O=C1NC(C(=O)O)Cc2ccccc21>>CC(=O)CCC(=S)N1C(=O)c2ccccc2CC1C(=O)O -US20090181942A1,7,COC(=O)CC1OC(c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(CC(C)C)ccc21>>COc1cccc([C@H]2O[C@H](CCO)c3ccc(CC(C)C)n3-c3ccc(Cl)cc32)c1OC -US05019574,1,C1CCNCC1.O=[N+]([O-])c1c(Br)c[n+]([O-])c2ccccc12>>O=[N+]([O-])c1c(N2CCCCC2)c[n+]([O-])c2ccccc12 -US05603959,7,CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O>>CCCCC/C=C\C/C=C\C/C=C\CCCCCO -US20060199966A1,2,CN[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1.O=C1CC[C@@H](C(=O)O)O1>>CN(C(=O)[C@@H]1CCC(=O)O1)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1 -US20100152443A1,2,COCN=C=S.Cc1cc(Oc2ccc(C#N)cc2C(F)(F)F)n[nH]1>>COCNC(=S)n1nc(Oc2ccc(C#N)cc2C(F)(F)F)cc1C -US20090326229A1,1,Cc1ccccc1I.Cc1cnc(N)c(Br)c1>>Cc1cnc(Nc2ccccc2C)c(Br)c1 -US05919793,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.CCOc1cc(C=O)ccc1C#CC1(O)CN2CCC1CC2>>CCOC(=O)C=Cc1ccc(C#CC2(O)CN3CCC2CC3)c(OCC)c1 -US20070167449A1,6,COc1ccc(-c2cnc(Nc3ccc(OCCN4CCCC4)cc3)s2)cc1>>Oc1ccc(-c2cnc(Nc3ccc(OCCN4CCCC4)cc3)s2)cc1 -US20050239751A1,9,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCCC1c1oc(=O)oc1CO>>CC(C)(C)OC(=O)N1CCCC1c1oc(=O)oc1CBr -US20120184561A1,2,CCN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1.O=C(O)Cc1ccc(-n2cnc3cccnc32)cc1Cl>>CCN1CCN(Cc2ccc(NC(=O)Cc3ccc(-n4cnc5cccnc54)cc3Cl)cc2C(F)(F)F)CC1 -US20110118262A1,2,CO.O=C(O)c1ccc(Br)c(C(F)(F)F)c1>>COC(=O)c1ccc(Br)c(C(F)(F)F)c1 -US07192950B2,6,COC(=O)C(c1ccccc1)N1CCCc2cc(OC)c(OC)cc2C1Cc1ccc(OC)c(OC)c1>>COc1ccc(CC2c3cc(OC)c(OC)cc3CCCN2C(C(=O)O)c2ccccc2)cc1OC -US07728029B2,1,C1CCNC1.Cn1ncc(C(=O)NC2C3CC4CC(C3)CC2C4)c1Cl>>Cn1ncc(C(=O)NC2C3CC4CC(C3)CC2C4)c1N1CCCC1 -US20070219210A1,6,CCOC(=O)c1cc(-c2ccc(C#N)cc2)n(-c2cccnc2)n1>>N#Cc1ccc(-c2cc(C(=O)O)nn2-c2cccnc2)cc1 -US20140094465A1,6,COC(=O)c1ccc(CC(=O)c2ccc(O)cc2)cc1>>O=C(O)c1ccc(CC(=O)c2ccc(O)cc2)cc1 -US20130035326A1,3,CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.FC1(F)CCN(CCNc2ccc(Br)cn2)CC1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(NCCN3CCC(F)(F)CC3)nc2)cc1 -US20100137298A1,1,CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(O)cc2)cc1)C(=O)OC(C)(C)C.O=C(O)c1cc2ccccc2o1>>CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OC(=O)c3cc4ccccc4o3)cc2)cc1)C(=O)OC(C)(C)C -US20100048568A1,7,O=C1COc2ccc(F)cc2N1>>Fc1ccc2c(c1)NCCO2 -US20140187553A1,3,Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(-c4nnc(NC(C)C)o4)ccc32)cc1.O=C(NC1CC1)c1cnc(Br)s1>>Cc1ccc(S(=O)(=O)n2cc(-c3ncc(C(=O)NC4CC4)s3)c3cc(-c4nnc(NC(C)C)o4)ccc32)cc1 -US04341698,6,CNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)OC(C)(C)C>>CNC(=O)[C@H](Cc1ccccc1)NC(=O)CN -US20120058984A1,1,O=C1NCCO1.O[C@@H]1CC[C@@H](Nc2nc(Cc3ccccc3)cc(Nc3nc4ccc(Cl)nc4s3)n2)CC1>>O=C1OCCN1c1ccc2nc(Nc3cc(Cc4ccccc4)nc(N[C@@H]4CC[C@@H](O)CC4)n3)sc2n1 -US04282246,7,O=C(O)c1ccc(C(=O)c2ccccc2)s1>>O=C(O)c1ccc(Cc2ccccc2)s1 -US20060148867A1,1,Nc1ccc(S(=O)(=O)C(F)(F)F)cc1.O=S1(=O)N=C(O)c2ccc(-c3ncccc3Cl)cc21>>O=S1(=O)N=C(Nc2ccc(S(=O)(=O)C(F)(F)F)cc2)c2ccc(-c3ncccc3Cl)cc21 -US20150239878A1,2,CC(=O)OC(C)=O.COc1cc(Br)c(N)cc1OCc1ccccc1>>COc1cc(Br)c(NC(C)=O)cc1OCc1ccccc1 -US20140336190A1,3,CCOc1nc2c(I)cc(-c3c(C)noc3C)cc2[nH]1.Cn1ncc(-c2ccccc2)c1B1OC(C)(C)C(C)(C)O1>>CCOc1nc2c(-c3c(-c4ccccc4)cnn3C)cc(-c3c(C)noc3C)cc2[nH]1 -US20150166521A1,6,COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(C#Cc2cccc(NC(=O)c3occc3C)c2)c1>>Cc1ccoc1C(=O)Nc1cccc(C#Cc2cc(C(=O)N=S(C)(=O)CCCCC(=O)O)cnc2N)c1 -US08252935B2,6,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCN(Cc3cc(F)cc(C(F)(F)F)c3)CC2)c1>>CC(C)CC(C(=O)O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCN(Cc3cc(F)cc(C(F)(F)F)c3)CC2)c1 -US06538154B2,3,CC(=O)OC(C)=O.O=Cc1ccccc1>>O=C(O)C=Cc1ccccc1 -US20130045986A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.FC(F)(F)c1ccc(-c2nc3cc(Br)ccc3o2)cc1>>CC1(C)OB(c2ccc3oc(-c4ccc(C(F)(F)F)cc4)nc3c2)OC1(C)C -US04851586,1,C1=COCCC1.C=CCc1cc(OC)c2ccccc2c1O>>C=CCc1cc(OC)c2ccccc2c1OC1CCCCO1 -US06927214B1,1,CC(C)c1nc2cc(Cl)c(Cl)cc2nc1S.CCOC(=O)CCBr>>CCOC(=O)CCSc1nc2cc(Cl)c(Cl)cc2nc1C(C)C -US20070149532A1,1,CC(C)[C@]1(C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)C=C[C@@H](N)C1.CCOC(=O)N1CCC(=O)C(OC)C1>>CCOC(=O)N1CCC(N[C@@H]2C=C[C@@](C(=O)N3CCN(c4cc(C(F)(F)F)ccn4)CC3)(C(C)C)C2)C(OC)C1 -US20090156572A1,2,CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1C(=O)O.CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCNC[C@H]1c1ccc(Cl)c(Cl)c1>>CN(C(=O)c1ccc(Cl)cc1)[C@@H]1CCN(C(=O)[C@H]2C[C@@H](O)CN2C(=O)OC(C)(C)C)C[C@H]1c1ccc(Cl)c(Cl)c1 -US20110294836A1,1,CC(C)(C)OC(=O)N1CCC(c2cccc(O)c2)CC1.CS(=O)(=O)c1ccc(CCl)cc1>>CC(C)(C)OC(=O)N1CCC(c2cccc(OCc3ccc(S(C)(=O)=O)cc3)c2)CC1 -US05382598,2,Nc1ccc(S(=O)(=O)c2ccccn2)cc1.O=C(O)C(O)(C(F)F)C(F)F>>O=C(Nc1ccc(S(=O)(=O)c2ccccn2)cc1)C(O)(C(F)F)C(F)F -US20120101083A1,1,CC(C)(C)OC(=O)CBr.CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNC4)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CC(=O)OC(C)(C)C)C4)no2)cc1C#N -US08440830B2,1,CCOC(=O)CBr.Nc1ccc2c(c1)OCO2>>CCOC(=O)CNc1ccc2c(c1)OCO2 -US20050250797A1,1,CNC(=O)NCC#Cc1cc(Cl)c(N)c2c1OCO2.COc1cc2c(Cl)ncnc2cc1OCCCN1CCOCC1>>CNC(=O)NCC#Cc1cc(Cl)c(Nc2ncnc3cc(OCCCN4CCOCC4)c(OC)cc23)c2c1OCO2 -US20070117856A1,2,COCCN1CCNCC1=O.O=C(O)c1ccc(/C=C/c2n[nH]c3ccccc23)cc1>>COCCN1CCN(C(=O)c2ccc(/C=C/c3n[nH]c4ccccc34)cc2)CC1=O -US05451582,7,CS(=O)(=O)NC(=O)c1cccc([N+](=O)[O-])c1>>CS(=O)(=O)NC(=O)c1cccc(N)c1 -US20030065176A1,3,CC(C)(C)NS(=O)(=O)c1ccccc1B(O)O.COC(=O)c1ccc(Br)cc1>>COC(=O)c1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1 -US20090111794A1,1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2.ClCc1ccc(Cc2nc3ccccc3s2)cc1>>CC(C)(C)OC(=O)N1CC2CC1CN2Cc1ccc(Cc2nc3ccccc3s2)cc1 -US06949648B2,2,CCOC(=O)c1cnc2c(c(C)nn2-c2ccccn2)c1O.NCc1ccccc1>>Cc1nn(-c2ccccn2)c2ncc(C(=O)NCc3ccccc3)c(O)c12 -US20110306587A1,6,CN(C(=O)OC(C)(C)C)C1CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)C1>>CNC1CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)C1 -US06664411B2,1,CCOC(=O)C(Cc1ccc(O)cc1)OCC.O=C1c2ccccc2OCN1CCO>>CCOC(=O)C(Cc1ccc(OCCN2COc3ccccc3C2=O)cc1)OCC -US20130039906A1,3,CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](Oc2cccc(Br)n2)C1.C[Si](C)(C)CCOCn1nc([Sn](C)(C)C)c2cc(-c3cccnc3)ncc21>>CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](Oc2cccc(-c3nn(COCC[Si](C)(C)C)c4cnc(-c5cccnc5)cc34)n2)C1 -US20090149456A1,2,CN(C)CCOc1cccc(Nc2nccc(-c3c(-c4ccc(F)c(N)c4)nn4ccccc34)n2)c1.O=C(Cl)Cc1cccs1>>CN(C)CCOc1cccc(Nc2nccc(-c3c(-c4ccc(F)c(NC(=O)Cc5cccs5)c4)nn4ccccc34)n2)c1 -US04333942,1,CC(C)Br.O=[N+]([O-])c1ccc(OC2(c3ccccc3)CCNCC2)cc1>>CC(C)N1CCC(Oc2ccc([N+](=O)[O-])cc2)(c2ccccc2)CC1 -US04380638,1,ClCc1csc(=NC2NCCN2)[nH]1.NCCS>>NCCSCc1csc(=NC2NCCN2)[nH]1 -US20120065202A1,6,C[C@@H]1COCCN1c1nc(-c2ccc(NC(=O)NC3CC3)cc2F)nc2c1CN(C(=O)OC(C)(C)C)C2>>C[C@@H]1COCCN1c1nc(-c2ccc(NC(=O)NC3CC3)cc2F)nc2c1CNC2 -US05688946,2,N[C@@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1.O=C(O)c1nc2ccccc2[nH]1>>O=C(N[C@@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)C1CC1)c1nc2ccccc2[nH]1 -US20120277224A1,4,Nc1ccc(Br)cc1.OCC(O)CO>>Brc1ccc2ncccc2c1 -US20120028919A1,1,C1COCCN1.CC(C)(C)OC(=O)N1CCCC(=O)C1>>CC(C)(C)OC(=O)N1CCCC(N2CCOCC2)C1 -US20130045942A1,1,C[C@H](N)c1ccc(Cl)cc1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>C[C@H](Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)c1ccc(Cl)cc1 -US04701552,9,C[C@@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@H](C=O)NC(=O)OC(C)(C)C -US08637501B2,6,Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)nc31)CCN(C(=O)OC(C)(C)C)CC2>>Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)nc31)CCNCC2 -US08030332B2,1,Brc1ncccc1OC(c1cccnc1)c1cccnc1.c1ccc2c(c1)NCCO2>>c1cncc(C(Oc2cccnc2N2CCOc3ccccc32)c2cccnc2)c1 -US20080188528A1,6,CCOC(=O)c1cccn(Cc2ccc3cc(OC)ccc3c2)c1=O>>COc1ccc2cc(Cn3cccc(C(=O)O)c3=O)ccc2c1 -US07915411B2,1,Nc1ccc(S)cc1.O=[N+]([O-])c1cc(OCc2cnc(Cl)s2)ccc1Cl>>Nc1ccc(Sc2ccc(OCc3cnc(Cl)s3)cc2[N+](=O)[O-])cc1 -US07160915B2,7,C=Cc1ccc(NC2=CC3=NCN(C)C3=CC2(F)C(=O)OC)c(F)c1>>CCc1ccc(NC2=CC3=NCN(C)C3=CC2(F)C(=O)OC)c(F)c1 -US20110160202A1,3,COC1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=C(c1ccc(Oc2nccnc2Cl)cc1)c1nc2ccccc2[nH]1>>COC1CC=C(c2nccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1 -US20120121540A1,6,CC(C)(C)OC(=O)n1cccc1-c1cc(C(F)(F)F)c2nc(C(=O)NCc3cccs3)c(Cl)n2c1>>O=C(NCc1cccs1)c1nc2c(C(F)(F)F)cc(-c3ccc[nH]3)cn2c1Cl -US20130165412A1,2,Nc1ccc(F)cn1.O=C(O)c1nn(CC2CCOCC2)c2c1CC1CC21>>O=C(Nc1ccc(F)cn1)c1nn(CC2CCOCC2)c2c1C[C@H]1C[C@@H]21 -US20150141400A1,6,CCOC(=O)c1cc(C(F)(F)F)c(CN2CC[C@@H](N(C)C(=O)OC(C)(C)C)C2)cc1N>>CN(C(=O)OC(C)(C)C)[C@@H]1CCN(Cc2cc(N)c(C(=O)O)cc2C(F)(F)F)C1 -US20150175602A1,2,CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CCNC2.O=C(Cl)N1CCOCC1>>CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CCN(C(=O)N1CCOCC1)C2 -US20080255133A1,1,Nc1ccc(Br)cc1F.O=C(O)c1nnc(Cl)cc1Cl>>O=C(O)c1nnc(Cl)cc1Nc1ccc(Br)cc1F -US20070093484A1,1,CCOC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C=O.FC1(F)CCNCC1>>CCOC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1CN1CCC(F)(F)CC1 -US20100137340A1,7,O=C(NC1CCCCCC1)c1onc(-c2ccccc2)c1[N+](=O)[O-]>>Nc1c(-c2ccccc2)noc1C(=O)NC1CCCCCC1 -US07319097B2,1,C1CNCCN1.CCNc1cc(F)ccc1[N+](=O)[O-]>>CCNc1cc(N2CCNCC2)ccc1[N+](=O)[O-] -US20110136800A1,2,O=C(O)c1ccn2ccnc2c1.c1ccc2c(c1)C[C@@H]1NCCC[C@H]21>>O=C(c1ccn2ccnc2c1)N1CCC[C@@H]2c3ccccc3C[C@@H]21 -US20100048554A1,6,CN(C)C1(CC2CCCC2)CCC2(CC1)OCCO2>>CN(C)C1(CC2CCCC2)CCC(=O)CC1 -US06703392B2,1,BrCC1CC1.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NC1CCc3ccccc31)CC2>>COc1ccc(CC2c3cc(OCC4CC4)c(OC)cc3CCN2CC(=O)NC2CCc3ccccc32)cc1OC -US08524702B2,2,CC(C)(C)[Si](C)(C)O[C@@H]1CCNC1.CC1(C)OB(c2ccc(C(=O)O)cc2)OC1(C)C>>CC1(C)OB(c2ccc(C(=O)N3CC[C@@H](O[Si](C)(C)C(C)(C)C)C3)cc2)OC1(C)C -US05635197,1,CN1C(=O)CC[C@]2(C)c3ccc(C(=O)O)cc3CC[C@@H]12.Oc1ccccc1>>CN1C(=O)CC[C@]2(C)c3ccc(C(=O)Oc4ccccc4)cc3CC[C@@H]12 -US20140073650A1,6,CCCc1ccc(OCC(=O)OC(C)(C)C)cc1>>CCCc1ccc(OCC(=O)O)cc1 -US20110059936A1,3,C#C[Si](C)(C)C.CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(Br)cc1-c1nnnn1-c1cccc(F)c1F>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(C#C[Si](C)(C)C)cc1-c1nnnn1-c1cccc(F)c1F -US20130269064A1,1,CC=O.Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1NC(=O)c1cccc(N)c1F>>CCNc1cccc(C(=O)Nc2c(C(F)(F)F)c(C(F)(F)C(F)(F)F)nn2C)c1F -US20130203730A1,9,COC(=O)c1cc(-c2cccc(N(C)C)n2)ccc1Cl.N>>CN(C)c1cccc(-c2ccc(Cl)c(C(N)=O)c2)n1 -US07601837B2,7,O=[N+]([O-])c1cccc2cc(S(=O)(=O)c3ccccc3)cnc12>>Nc1cccc2cc(S(=O)(=O)c3ccccc3)cnc12 -US20100093757A1,1,CC(C)[Si](OC[C@@H](C)OC[C@H](O)C(=O)Nc1ccccn1)(C(C)C)C(C)C.Clc1ccccc1-n1ncc2c(Cl)ncnc21>>CC(C)[Si](OC[C@@H](C)OC[C@H](Oc1ncnc2c1cnn2-c1ccccc1Cl)C(=O)Nc1ccccn1)(C(C)C)C(C)C -US04808581,3,C=CC(=O)N(C)C.Cc1ccc(S(=O)(=O)n2cc(I)nc2C)cc1>>Cc1ccc(S(=O)(=O)n2cc(/C=C/C(=O)N(C)C)nc2C)cc1 -US07368578B2,6,CCOC(=O)c1cn(Cc2ccccc2)nc1OCc1ccc(OCc2nc(-c3ccco3)oc2C)c(OCc2ccccc2)c1>>Cc1oc(-c2ccco2)nc1COc1ccc(COc2nn(Cc3ccccc3)cc2C(=O)O)cc1OCc1ccccc1 -US20150141400A1,6,CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(C3OCCO3)c(OC(F)(F)F)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(C=O)c(OC(F)(F)F)cc2c1=O -US05496927,2,CC(C)C(N)C(O)C(F)(F)F.C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O>>CC(C)C(NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(O)C(F)(F)F -US05864039,1,COc1cc(N)c(Cl)cc1C(=O)NCC1CCNCC1.Fc1ccc(OCCCCCBr)cc1>>COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCCCOc2ccc(F)cc2)CC1 -US08927536B2,3,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(B5OC(C)(C)C(C)(C)O5)cc4)CC3)n2CCS1.Clc1cccnn1>>CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(-c5cccnn5)cc4)CC3)n2CCS1 -US08716312B2,2,CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCCNCC4)nc3)o2)C1.O=S(=O)(Cl)Cc1ccccc1>>CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCCN(S(=O)(=O)Cc5ccccc5)CC4)nc3)o2)C1 -US06548493B1,1,O=C(CCCCl)c1ccc(F)cc1.c1cc2c3c(c1)[C@@H]1CNCC[C@@H]1N3CCC2>>O=C(CCCN1CC[C@H]2[C@@H](C1)c1cccc3c1N2CCC3)c1ccc(F)cc1 -US08569522B2,2,CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)O)cc3)c(Cl)cc21.NCC1Cc2ccccc2C1>>CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)NCC4Cc5ccccc5C4)cc3)c(Cl)cc21 -US04170705,8,CNC(=O)c1c(-c2ccccc2)noc1CC(O)c1ccccc1>>CNC(=O)c1c(-c2ccccc2)noc1CC(=O)c1ccccc1 -US08247429B2,7,CCOC(=O)c1cnn2ccc3c(c12)C(CC#N)CC3>>CCOC(=O)c1cnn2ccc3c(c12)C(CCN)CC3 -US20070275968A1,3,CSc1ccc(B(O)O)cc1.Cc1cccc(-c2[nH]c(C(C)C)nc2-c2cccc(Br)c2)n1>>CSc1ccc(-c2cccc(-c3nc(C(C)C)[nH]c3-c3cccc(C)n3)c2)cc1 -US05547949,1,C1CNCCN1.CC(C)(C)CNc1cc(Cl)nc(NC(C)(C)C)n1>>CC(C)(C)CNc1cc(N2CCNCC2)nc(NC(C)(C)C)n1 -US20120088750A1,1,CCOC(=O)C1(CC)CCNCC1.Clc1nsc(Cl)n1>>CCOC(=O)C1(CC)CCN(c2nc(Cl)ns2)CC1 -US09156811B2,2,Cc1c(N)cnn1C.O=S(=O)(Cl)c1c(Cl)cc(Br)cc1Cl>>Cc1c(NS(=O)(=O)c2c(Cl)cc(Br)cc2Cl)cnn1C -US09085570B2,2,Cc1oc(-c2ccc(C(=O)O)cc2)nc1CS(=O)(=O)c1ccc(Br)cc1.NCc1cccnc1>>Cc1oc(-c2ccc(C(=O)NCc3cccnc3)cc2)nc1CS(=O)(=O)c1ccc(Br)cc1 -US07247633B2,1,Clc1cncc(Cl)n1.NCc1ccccc1>>Clc1cncc(NCc2ccccc2)n1 -US05688945,1,BrCc1ccccc1.Cc1cc([N+](=O)[O-])c(O)c(Cl)c1C>>Cc1cc([N+](=O)[O-])c(OCc2ccccc2)c(Cl)c1C -US08404707B2,8,CC(C)(C)c1cn2cccc(CO)c2n1>>CC(C)(C)c1cn2cccc(C=O)c2n1 -US20120178732A1,1,COC(=O)CBr.Oc1ccc(C(F)(F)F)cc1Br>>COC(=O)COc1ccc(C(F)(F)F)cc1Br -US09153785B2,8,CSc1ccsc1Br.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccsc1Br -US20150119392A1,2,C=C(C)OC(=O)Cl.CSc1ncc2cc(-c3cc(N)c(F)cc3Br)c(C)nc2n1>>C=C(C)OC(=O)Nc1cc(-c2cc3cnc(SC)nc3nc2C)c(Br)cc1F -US05652235,7,O=C1CC2(CCNCC2)c2ccccc21>>c1ccc2c(c1)CCC21CCNCC1 -US20090023798A1,2,CCOC(=O)c1ccc(OCCN)cc1.O=C(O)c1cc2ccccc2o1>>CCOC(=O)c1ccc(OCCNC(=O)c2cc3ccccc3o2)cc1 -US08895313B2,7,Cc1ccc2nc(-c3ccc(NC(=O)c4ccccc4[N+](=O)[O-])cc3)sc2c1>>Cc1ccc2nc(-c3ccc(NC(=O)c4ccccc4N)cc3)sc2c1 -US20070142352A1,7,C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc(N)c1N=O>>C[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc(N)c1N -US06359138B1,1,BrCC1Cc2cc(OCc3ccccc3)ccc2O1.Cc1ccc(CC2(O)CCNCC2)cc1>>Cc1ccc(CC2(O)CCN(CC3Cc4cc(OCc5ccccc5)ccc4O3)CC2)cc1 -US20080132525A1,1,CC(C)(C)OC(=O)[C@H](CCNC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)NC(=O)OCc1ccccc1.O=C/C=C/c1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)[C@H](CCN(CC=Cc1ccccc1[N+](=O)[O-])C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)NC(=O)OCc1ccccc1 -US07595320B2,6,CCOC(=O)c1cc2c(NC(=O)c3ccc(OC)cc3)nn(C(C)OCC)c2s1>>CCOC(C)n1nc(NC(=O)c2ccc(OC)cc2)c2cc(C(=O)O)sc21 -US08247430B2,1,N#Cc1ccnc(Cl)c1.OCC(F)(F)F>>N#Cc1ccnc(OCC(F)(F)F)c1 -US20040110826A1,2,CCC(=O)OC(=O)CC.Nc1ncc(CN2CCN(c3ccccc3)CC2)c2nc(-c3ccco3)nn12>>CCC(=O)Nc1ncc(CN2CCN(c3ccccc3)CC2)c2nc(-c3ccco3)nn12 -US20080021217A1,2,CC(C)(C)C(=O)Oc1ccc(C(=O)O)c(OC(=O)C(C)(C)C)c1.NCc1nc(-c2ccncc2)n[nH]1>>CC(C)(C)C(=O)Oc1ccc(C(=O)NCc2nc(-c3ccncc3)n[nH]2)c(OC(=O)C(C)(C)C)c1 -US20110166121A1,6,CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(COc3ccccc3C(=O)OC)nc2s1>>CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(COc3ccccc3C(=O)O)nc2s1 -US07544812B2,6,CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3ccc(Cl)c(Cl)c3)C(=O)N2C)cc1)Oc1ccccc1>>CN1C(=O)N(Cc2ccc(Cl)c(Cl)c2)CC1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 -US20140296515A1,1,CCNCC(F)(F)F.N#Cc1c(Cl)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1ccc(OCCO)cc1>>CCN(CC(F)(F)F)c1nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c(-c2ccc(OCCO)cc2)c1C#N -US20050130968A1,1,COCC(C)N.Clc1cccc(Nc2ncnc(-c3ccnc(Cl)c3)n2)c1>>COCC(C)Nc1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1 -US05889026,1,CC(C)(C)[Si](C)(C)Oc1ccc(NC(=O)CCl)cc1.OC1(Cc2ccc(Cl)cc2)CCNCC1>>CC(C)(C)[Si](C)(C)Oc1ccc(NC(=O)CN2CCC(O)(Cc3ccc(Cl)cc3)CC2)cc1 -US20080300242A1,1,CCCN1CCC(c2cc(OC)c(N)cc2C)CC1.O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)c1>>CCCN1CCC(c2cc(OC)c(Nc3nccc(-c4c(-c5cccc(C(=O)Nc6c(F)cccc6F)c5)nc5ccccn45)n3)cc2C)CC1 -US20050085458A1,6,CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(c2)NC(=O)CC3)CC1>>O=C1CCc2ccc(OC3CCNCC3)cc2N1 -US08637525B2,1,C1CNC1.FC(F)(F)Oc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1>>FC(F)(F)Oc1ccc(C2CCc3c2nc(Cl)nc3N2CCC2)cc1 -US07700595B2,1,COC(=O)Cc1ccc(CBr)cc1.Cc1nnc2c(Cl)cccc2c1-c1cccc(O)c1>>COC(=O)Cc1ccc(COc2cccc(-c3c(C)nnc4c(Cl)cccc34)c2)cc1 -US20060183754A1,2,CCOC(=O)C(C)(C)Oc1ccc(OCC(=O)O)cc1C.Nc1cccc(-c2ccc(C(F)(F)F)cc2)c1>>CCOC(=O)C(C)(C)Oc1ccc(OCC(=O)Nc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1C -US05071465,6,COCOc1ccccc1C1(c2ccc(C)cc2OC)CC1>>COc1cc(C)ccc1C1(c2ccccc2O)CC1 -US20060276496A1,9,NO.O=C(Nc1cccnc1)c1ccc2[nH]c3c(c2c1)CCCC3=O>>O=C(Nc1cccnc1)c1ccc2[nH]c3c(c2c1)CCCC3=NO -US04933157,6,CCOC(=O)CCCCCCCCCCCc1cccc(I)c1>>O=C(O)CCCCCCCCCCCc1cccc(I)c1 -US06057335,6,COC(=O)C1Cc2cccc(-c3ccccc3)c2C1>>O=C(O)C1Cc2cccc(-c3ccccc3)c2C1 -US06982348B2,6,CCOC(=O)C(Cc1ccc(C(C)(C)CC)cc1)C(O)c1cccc(Cl)c1>>CCC(C)(C)c1ccc(CC(C(=O)O)C(O)c2cccc(Cl)c2)cc1 -US06593300B1,6,COC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(C)C>>COC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C -US20080306064A1,6,COC(=O)c1c(S(=O)(=O)Cc2ccccc2)ccc2nc(Nc3cccc(Cl)c3Cl)[nH]c12>>O=C(O)c1c(S(=O)(=O)Cc2ccccc2)ccc2nc(Nc3cccc(Cl)c3Cl)[nH]c12 -US20110275797A1,6,CC(C)(C)OC(=O)c1ccc(-c2cccs2)cc1NC(=O)c1cc(N2CCCCC2)ccc1O>>O=C(Nc1cc(-c2cccs2)ccc1C(=O)O)c1cc(N2CCCCC2)ccc1O -US20060183755A1,3,Brc1cnc2c(-c3ccccc3)cnn2c1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2cnc3c(-c4ccccc4)cnn3c2)cc1 -US20090029994A1,6,CCOC(=O)CCCOc1cnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2Oc2ncccn2)nc1>>O=C(O)CCCOc1cnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2Oc2ncccn2)nc1 -US07084169B2,1,Cc1cccc(O)c1[N+](=O)[O-].ClCCN1CCCC1>>Cc1cccc(OCCN2CCCC2)c1[N+](=O)[O-] -US06288082B1,1,CCOc1cc2ncc(C#N)c(Cl)c2cc1OCC.Nc1ccc2cc[nH]c2c1>>CCOc1cc2ncc(C#N)c(Nc3ccc4cc[nH]c4c3)c2cc1OCC -US20050070592A1,6,COc1ccc(-c2ccc3c(c2)c2c(n3Cc3ccccc3)CCCC2)cc1>>Oc1ccc(-c2ccc3c(c2)c2c(n3Cc3ccccc3)CCCC2)cc1 -US06407094B1,2,CC(C)(C)OC(=O)CC(=O)c1ccc(C#N)s1.CC(C)(C)OC(=O)Nc1cc(OC(C)(C)C)c(-c2ccccc2F)cc1N>>CC(C)(C)OC(=O)Nc1cc(OC(C)(C)C)c(-c2ccccc2F)cc1NC(=O)CC(=O)c1ccc(C#N)s1 -US20120149694A1,3,COC(=O)Cc1cncc(Br)c1.OB(O)c1ccc(C(F)(F)F)cc1>>COC(=O)Cc1cncc(-c2ccc(C(F)(F)F)cc2)c1 -US20100144787A1,6,COC(=O)COc1ccc(Cl)c2nc(OC)c(Cc3ccc(-n4cccn4)cc3)c(C)c12>>COc1nc2c(Cl)ccc(OCC(=O)O)c2c(C)c1Cc1ccc(-n2cccn2)cc1 -US20090318523A1,7,CCCOc1c2c(c(OCCC)c3ccccc13)C(=O)N(c1ccc(CC(=O)OCC)cc1C)C2=O>>CCCOc1c2c(c(OCCC)c3ccccc13)C(O)N(c1ccc(CC(=O)OCC)cc1C)C2=O -US20090099177A1,3,CC(C)COc1ccc(Cl)cc1B(O)O.CCOC(=O)c1cccc(CBr)n1>>CCOC(=O)c1cccc(Cc2cc(Cl)ccc2OCC(C)C)n1 -US07919510B2,2,CCN(CC)CCNc1ccc([N+](=O)[O-])cc1N.CCOc1ccc(CC(=O)O)cc1>>CCOc1ccc(CC(=O)Nc2cc([N+](=O)[O-])ccc2NCCN(CC)CC)cc1 -US07482462B2,2,NS(=O)(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(NC1CCCCC1)C1CCN(C(C(=O)O)c2ccc(Cl)cc2)CC1>>O=C(NC1CCCCC1)C1CCN(C(C(=O)NS(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccc(Cl)cc2)CC1 -US07902201B2,2,CC(C)N.O=C(O)c1cnc(OCc2conc2-c2ccccn2)cn1>>CC(C)NC(=O)c1cnc(OCc2conc2-c2ccccn2)cn1 -US20150152058A1,2,CCC(=O)CNc1cnccc1-c1ccc(F)cc1OC.CS(=O)(=O)c1cc(C(=O)O)cc(C(F)(F)F)c1>>CCC(=O)CN(C(=O)c1cc(C(F)(F)F)cc(S(C)(=O)=O)c1)c1cnccc1-c1ccc(F)cc1OC -US20100016330A1,2,O=C(O)c1cnn2cccnc12.O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCNCC1>>O=C(c1cnn2cccnc12)N1CCN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1 -US07625908B2,7,CC(C)(Oc1ccc([N+](=O)[O-])cc1Cl)c1ccccn1>>CC(C)(Oc1ccc(N)cc1Cl)c1ccccn1 -US20060148858A1,3,C=CC(=O)OC.CC(C)c1nn(Cc2ccccc2)cc1I>>COC(=O)/C=C/c1cn(Cc2ccccc2)nc1C(C)C -US20130131075A1,2,COc1ccc(N(C)c2ccc(CN)cc2)c(C)c1.O=C(NC1(C(=O)O)CC1)c1cncnc1>>COc1ccc(N(C)c2ccc(CNC(=O)C3(NC(=O)c4cncnc4)CC3)cc2)c(C)c1 -US20100210592A1,1,CC(C)(C)OC(=O)NC(C(=O)c1ccc(O)cc1)c1ccc(Cl)cc1.OC1CCCCC1>>CC(C)(C)OC(=O)NC(C(=O)c1ccc(OC2CCCCC2)cc1)c1ccc(Cl)cc1 -US20150175602A1,2,CS(=O)(=O)Cl.Fc1ccc(OC2CCN(c3nc4c(nc3NCC(F)F)CCNC4)CC2)c(F)c1>>CS(=O)(=O)N1CCc2nc(NCC(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2C1 -US04105790,3,COC(=O)CCc1ccccc1.O=C(Cl)CCl>>COC(=O)CCc1ccc(C(=O)CCl)cc1 -US03989739,3,C=CCCl.CC(C)=CCC/C(C)=C/CCl>>C=CCCC=C(C)CCC=C(C)C -US20090253685A1,7,O=[N+]([O-])c1cccc2oc(-c3c(F)cccc3F)nc12>>Nc1cccc2oc(-c3c(F)cccc3F)nc12 -US20060189591A1,2,CCOC(=O)C(N)C(=O)OCC.Cc1ccc(C(=O)O)nc1>>CCOC(=O)C(NC(=O)c1ccc(C)cn1)C(=O)OCC -US06013656,2,C(=C/c1ccccc1)\CC1CCCCN1.O=C(O)C1CCC1>>O=C(C1CCC1)N1CCCCC1C/C=C/c1ccccc1 -US20090291948A1,1,COC(=O)CBr.Oc1cccc2[nH]ccc12>>COC(=O)COc1cccc2[nH]ccc12 -US08952169B2,6,C/C=C/c1cc(C(=O)OC(C)(C)C)c(F)cc1OCC12CC3CC(CC(C3)C1)C2>>C/C=C/c1cc(C(=O)O)c(F)cc1OCC12CC3CC(CC(C3)C1)C2 -US20140148451A1,1,CCN1CCC(N)CC1.COc1ccc2nc3cc(Cl)ccc3c(Cl)c2c1>>CCN1CCC(Nc2c3ccc(Cl)cc3nc3ccc(OC)cc23)CC1 -US20100324010A1,6,CCC1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1cnc(C(C)C)nc1NCc1ccco1>>CCC1CNCCN1C(=O)c1cnc(C(C)C)nc1NCc1ccco1 -US04331683,7,CCCCCCCCNC(=O)[C@@H]1C[C@H]1c1ccc([N+](=O)[O-])cc1>>CCCCCCCCNC(=O)[C@@H]1C[C@H]1c1ccc(N)cc1 -US20060287309A1,1,CC(C)(C)OC(=O)N1CCNCC1.O=S(=O)(Oc1cccc2cc(F)c(F)cc12)C(F)(F)F>>CC(C)(C)OC(=O)N1CCN(c2cccc3cc(F)c(F)cc23)CC1 -US06414179B1,2,CNCCO.O=C(O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>CN(CCO)C(=O)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 -US08835457B2,1,Cc1ccc(C=O)cc1OCCO.c1cc2[nH]ncc2cc1NC1C2CCC1NC2>>Cc1ccc(CN2CC3CCC2C3Nc2ccc3[nH]ncc3c2)cc1OCCO -US06201025B1,1,COc1ccccc1CN.O=C1CCc2ccccc2C1Cc1ccccc1>>COc1ccccc1CNC1CCc2ccccc2C1Cc1ccccc1 -US20150210688A1,3,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(C)cc1C.Cc1nc(C2COC2)[nH]c1I>>COC(=O)c1cc(-c2[nH]c(C3COC3)nc2C)c(C)cc1C -US20080176848A1,6,CC(C)(C)OC(=O)/C=C/c1ccn(S(=O)(=O)c2cccc(Br)c2)c1>>O=C(O)/C=C/c1ccn(S(=O)(=O)c2cccc(Br)c2)c1 -US07498354B2,2,CO.O=C(O)c1cc2c(ncn2-c2cccc(-c3ccsc3)c2)[nH]1>>COC(=O)c1cc2c(ncn2-c2cccc(-c3ccsc3)c2)[nH]1 -US20080021010A1,2,CCCS(=O)(=O)N1CC(CN)(c2ccccn2)C1.O=C(Cl)c1ccc(Cl)cc1Cl>>CCCS(=O)(=O)N1CC(CNC(=O)c2ccc(Cl)cc2Cl)(c2ccccn2)C1 -US20110201643A1,6,Cc1ccc(C(=O)N2CCc3ccc(C(=O)NOC4CCCCO4)cc3C2)cc1>>Cc1ccc(C(=O)N2CCc3ccc(C(=O)NO)cc3C2)cc1 -US07795282B2,6,CC(C)(C)[Si](OCCC1(c2ccccc2)SC(c2cc(F)ccc2F)=NN1C(=S)NC(=O)c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCCC1(c2ccccc2)SC(c2cc(F)ccc2F)=NN1C(N)=S)(c1ccccc1)c1ccccc1 -US05877196,6,O=C1c2ccccc2C(=O)N1CCCCCOc1ccc(-n2ccnc2)cc1>>NCCCCCOc1ccc(-n2ccnc2)cc1 -US20100035863A1,3,Nc1nc(Cl)cc(Cl)n1.[Zn+]C1C2CC3CC(C2)CC1C3>>Nc1nc(Cl)cc(C2C3CC4CC(C3)CC2C4)n1 -US20110306626A1,7,C[Si](C)(C)CCOCN1C(=O)C2(Cc3cc([N+](=O)[O-])cnc3C2)c2cccnc21>>C[Si](C)(C)CCOCN1C(=O)C2(Cc3cc(N)cnc3C2)c2cccnc21 -US20110039861A1,3,COc1cc2c(cn1)c(C(=O)N1CCN(C(=O)OC(C)(C)C)CC1)c(Cl)n2-c1ccccc1.Cc1c(F)cccc1CBr>>COc1cc2c(cn1)c(C(=O)N1CCN(C(=O)OC(C)(C)C)CC1)c(Cc1cccc(F)c1C)n2-c1ccccc1 -US20110319411A1,7,O=C1c2c(cccc2[N+](=O)[O-])CN1c1cccc(C(F)(F)F)c1>>Nc1cccc2c1C(=O)N(c1cccc(C(F)(F)F)c1)C2 -US06498251B1,1,OCCBr.c1ccc(CNCc2ccoc2)cc1>>OCCN(Cc1ccccc1)Cc1ccoc1 -US20140094474A1,2,C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.C[Si](C)(C)CCOCn1cc(C(=O)O)nc1C(N)=O>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cn(COCC[Si](C)(C)C)c(C(N)=O)n1 -US20090131409A1,2,CC(C)OC(=O)C1CNCC(C)(C)c2cc(C#N)[nH]c21.O=C(Cl)c1ccc(F)c(F)c1>>CC(C)OC(=O)C1CN(C(=O)c2ccc(F)c(F)c2)CC(C)(C)c2cc(C#N)[nH]c21 -US08106215B2,2,CC1C[C@H]2CN[C@H](CNC(=O)C(F)(F)F)[C@H]2C1.Cc1cccc(-c2sc(C)nc2C(=O)O)c1>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3CC(C)C[C@@H]3[C@H]2CNC(=O)C(F)(F)F)c1 -US20150239827A1,7,CCOC(=O)C=C[C@@H]1Cc2ccccc2C2(C1)OCCO2>>CCOC(=O)CC[C@@H]1Cc2ccccc2C2(C1)OCCO2 -US20120245161A1,2,COCCn1cc(C(=O)O)c2c(C(=O)N(C)C)cccc21.O=C(NCc1ccc(F)c(C2CCNCC2)c1)C(F)(F)F>>COCCn1cc(C(=O)N2CCC(c3cc(CNC(=O)C(F)(F)F)ccc3F)CC2)c2c(C(=O)N(C)C)cccc21 -US20090281092A1,1,CC(C)N1CC(F)(F)C(=O)Nc2cnc(Cl)nc21.CI>>CC(C)N1CC(F)(F)C(=O)N(C)c2cnc(Cl)nc21 -US20070249612A1,1,CC(C)(C)c1cn2c(=O)[nH]nc2c(Cl)n1.NCCO>>CC(C)(C)c1cn2c(=O)[nH]nc2c(NCCO)n1 -US20060194837A1,1,CN1Cc2cc(O)ccc2C(c2ccsc2)C1.ClCCCBr>>CN1Cc2cc(OCCCCl)ccc2C(c2ccsc2)C1 -US07163954B2,4,CCCCC(=O)c1c(-c2ccc3c(Br)c(OCC#N)ccc3c2)sc2ccccc12.[N-]=[N+]=[N-]>>CCCCC(=O)c1c(-c2ccc3c(Br)c(OCc4nnn[nH]4)ccc3c2)sc2ccccc12 -US04518603,1,CN(C)CCCCl.O=C(c1ccccc1)c1ccccc1Nc1ncccc1[N+](=O)[O-]>>CN(C)CCCN(c1ccccc1C(=O)c1ccccc1)c1ncccc1[N+](=O)[O-] -US20090221645A1,7,O=CC1=C(c2cccc3ccc(Cl)cc23)N2CCN=C2S1>>OCC1=C(c2cccc3ccc(Cl)cc23)N2CCN=C2S1 -US20090018056A1,6,CCS(=O)(=O)c1ccc(Oc2cc(OCOC)cc(C(=O)OC)c2)cn1>>CCS(=O)(=O)c1ccc(Oc2cc(O)cc(C(=O)OC)c2)cn1 -US07253192B2,1,CCOC(=O)C(C)(C)Oc1ccc(O)c(F)c1.CS(=O)(=O)OCCCC#Cc1ccc(OC(F)(F)F)cc1>>CCOC(=O)C(C)(C)Oc1ccc(OCCCC#Cc2ccc(OC(F)(F)F)cc2)c(F)c1 -US20130231477A1,3,Clc1cccnc1Cl.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ncccc2Cl)cc1 -US20070049618A1,2,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(O)c1cc2ccccc2o1>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)c4cc5ccccc5o4)c3C2=O)C(=O)N1 -US08664220B2,2,Cc1noc(-c2ccc(Br)cc2)c1C(=O)O.O=S(=O)(c1ccc(Cl)c(Cl)c1)N1CCNCC1>>Cc1noc(-c2ccc(Br)cc2)c1C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)c(Cl)c2)CC1 -US20050020591A1,2,COC(=O)C[C@H]1Nc2ccccc2NC1=O.O=C(Cl)c1ccc(F)c(F)c1>>COC(=O)C[C@@H]1C(=O)Nc2ccccc2N1C(=O)c1ccc(F)c(F)c1 -US20090281139A1,9,CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(B3OCC(C)(C)CO3)cc2C)cc1C#N>>CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(B(O)O)cc2C)cc1C#N -US20130281433A1,6,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccn4nnc(C)c4c3)sc2c1-c1ccc(Cl)cc1>>Cc1cc2nc(-c3ccn4nnc(C)c4c3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O -US07858640B2,1,Cc1nc2c(Cl)ccc(O)c2c(C)c1Cc1ccc(Cl)cc1.N#CCBr>>Cc1nc2c(Cl)ccc(OCC#N)c2c(C)c1Cc1ccc(Cl)cc1 -US20090029985A1,1,Clc1cc2c(nn1)-c1ccccc1CC2.c1ccc(N2CCNCC2)cc1>>c1ccc(N2CCN(c3cc4c(nn3)-c3ccccc3CC4)CC2)cc1 -US06322775B1,9,CCOC(=O)C1NN(C(C)(C)C)C(=O)C1=O>>CC(C)(C)N1NCC(=O)C1=O -US20130252890A1,1,O=S(=O)(CCCNCCF)CCCC(F)(F)C(F)(F)F.Oc1ccc2c(c1)CCCC(c1ccc(F)cc1)=C2CCCCCCBr>>O=S(=O)(CCCN(CCF)CCCCCCC1=C(c2ccc(F)cc2)CCCc2cc(O)ccc21)CCCC(F)(F)C(F)(F)F -US07638629B2,6,CCOC(=O)C(C)C1CCN(c2ccc(C(C)C)cc2)C(c2ccc(C(F)(F)F)cc2)C1>>CC(C)c1ccc(N2CCC(C(C)C(=O)O)CC2c2ccc(C(F)(F)F)cc2)cc1 -US20070105836A1,2,Clc1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1N2.O=C(Cl)OCc1ccc([N+](=O)[O-])cc1>>O=C(OCc1ccc([N+](=O)[O-])cc1)N1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 -US20140243302A1,3,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Cc1ccc([N+](=O)[O-])c(Cl)n1>>C=C(OCC)c1nc(C)ccc1[N+](=O)[O-] -US07335660B2,7,CC(C)(C)[Si](OCC[C@@H]1OCCc2cc(C=O)ccc21)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCC[C@@H]1OCCc2cc(CO)ccc21)(c1ccccc1)c1ccccc1 -US20040235822A1,8,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4ncn(C)n4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4ncn(C)n4)cc2)CCN3CC(C)C)cc1 -US20040176602A1,1,CCN1CCNCC1.Clc1ccc(Br)cn1>>CCN1CCN(c2ccc(Cl)nc2)CC1 -US08580832B2,3,N#Cc1ccc(Oc2ccc(C=O)cc2F)c(C(F)(F)F)c1.O=C1CSC(=S)N1>>N#Cc1ccc(Oc2ccc(C=C3SC(=S)NC3=O)cc2F)c(C(F)(F)F)c1 -US09115134B2,7,Fc1ccc(-c2ccc3nnc(Cl)n3n2)cc1>>Fc1ccc(C2=Nn3c(Cl)nnc3CC2)cc1 -US08420642B2,4,NC(=S)Nc1ncc(Oc2ccccc2)cc1OCC1CCCC1.O=CCCl>>c1ccc(Oc2cnc(Nc3nccs3)c(OCC3CCCC3)c2)cc1 -US20080027065A1,2,CNc1ccc(CN2CCN(C(=O)OC(C)(C)C)[C@@H](C)C2)cc1.O=C(O)c1ccc(-c2ccccn2)cc1>>C[C@H]1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4ccccn4)cc3)cc2)CCN1C(=O)OC(C)(C)C -US06156905,8,CCC(O)C(C)(C)C1CCOC(C)(C)O1>>CCC(=O)C(C)(C)C1CCOC(C)(C)O1 -US04835180,2,Nc1cc(Cl)c(O)c(Cl)c1.O=C(Cl)CCCCCBr>>O=C(CCCCCBr)Nc1cc(Cl)c(O)c(Cl)c1 -US04343945,2,Nc1nc(C(Cl)(Cl)Cl)ns1.O=C(Cl)c1ccccc1Cl>>O=C(Nc1nc(C(Cl)(Cl)Cl)ns1)c1ccccc1Cl -US20110262352A1,2,Clc1cccc(N2CCNCC2)c1Cl.O=C(Cl)C1COc2ccccc2O1>>O=C(C1COc2ccccc2O1)N1CCN(c2cccc(Cl)c2Cl)CC1 -US20110207704A1,1,CC(C)Oc1ccc(-c2noc(-c3ccc(F)cc3)n2)cc1C(F)(F)F.OCC1CNCCO1>>CC(C)Oc1ccc(-c2noc(-c3ccc(OCC4CNCCO4)cc3)n2)cc1C(F)(F)F -US04948898,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C=C(C)[C@@H]1[C@H](N)C(=O)N1Cc1ccc(OC)cc1OC>>CCOC(=O)C=C(C)[C@@H]1[C@H](NC(=O)OC(C)(C)C)C(=O)N1Cc1ccc(OC)cc1OC -US20060079548A1,3,Brc1ncccn1.C[Sn](C)(C)c1cc2nccc(Cl)c2s1>>Clc1ccnc2cc(-c3ncccn3)sc12 -US20100035917A1,2,CNC.O=C(O)Cc1cc2c(Br)ccnc2[nH]1>>CN(C)C(=O)Cc1cc2c(Br)ccnc2[nH]1 -US20090163471A1,6,COC(=O)c1ccc(N2CCN(C)CC2)c(F)c1>>CN1CCN(c2ccc(C(=O)O)cc2F)CC1 -US08802712B2,1,CCI.COc1cc2ncc3[nH]nc(-c4ccc(C#N)cc4)c3c2cc1OC>>CCn1nc(-c2ccc(C#N)cc2)c2c3cc(OC)c(OC)cc3ncc21 -US04496571,2,FC(F)(F)CN=C=S.Nc1ccnc(SCC#CCN2C(=O)c3ccccc3C2=O)n1>>O=C1c2ccccc2C(=O)N1CC#CCSc1nccc(NC(=S)NCC(F)(F)F)n1 -US20050075365A1,9,CC(C)c1nnc2ccc(Sc3ccccc3CN=[N+]=[N-])cn12>>CC(C)c1nnc2ccc(Sc3ccccc3CN)cn12 -US20120142667A1,7,COC(=O)COc1cccc([N+](=O)[O-])c1C>>COC(=O)COc1cccc(N)c1C -US08268859B2,5,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSc1ncc(N)c(Br)n1>>CSc1ncc(NC(=O)OC(C)(C)C)c(Br)n1 -US20130296344A1,1,CI.COc1cc(C2C(C#N)=C(N)Oc3c2ccc2c(N)cccc32)cc(Br)c1OC>>CNc1cccc2c3c(ccc12)C(c1cc(Br)c(OC)c(OC)c1)C(C#N)=C(N)O3 -US20150105401A1,3,COc1cc(-c2cnc3c(c2)CC(=O)N3)cc(OC)c1OC.N#Cc1ccc(C=O)cc1>>COc1cc(-c2cnc3c(c2)C(=Cc2ccc(C#N)cc2)C(=O)N3)cc(OC)c1OC -US20150238473A1,3,O=C(CCCN1CCC(C(O)(c2ccccc2)c2ccccc2)CC1)c1ccc(Br)cc1.OB(O)c1ccccc1>>O=C(CCCN1CCC(C(O)(c2ccccc2)c2ccccc2)CC1)c1ccc(-c2ccccc2)cc1 -US05736548,1,CN(C)CCCl.O=Cc1cccc(O)c1>>CN(C)CCOc1cccc(C=O)c1 -US04165333,1,C=C(C)C(=O)Cl.CC(C)(C)c1cc(CS)cc(C(C)(C)C)c1O>>C=C(C)C(=O)SCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 -US07514470B2,1,CCC(Br)C(=O)OC(C)(C)C.N#Cc1ccc(NCC(F)(F)F)cc1Cl>>CCC(C(=O)OC(C)(C)C)N(CC(F)(F)F)c1ccc(C#N)c(Cl)c1 -US20080004309A1,9,CCOC(=O)c1nc(Br)c2c(c1O)c(Br)c(Br)n2Cc1ccc(OC)cc1.N#C[Cu]>>CCOC(=O)c1nc(C#N)c2c(c1O)c(Br)c(Br)n2Cc1ccc(OC)cc1 -US07745479B2,1,CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1.COc1ncc(B(O)O)cn1>>COc1ncc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(OC4CCN(C(C)C)CC4)ccc32)cn1 -US20060292060A1,1,CCOC(=O)CCCCCBr.Oc1ccc(I)cc1>>CCOC(=O)CCCCCOc1ccc(I)cc1 -US04835275,7,CN(C)CCNc1c2c(nc3ccccc13)CCCC2=O>>CN(C)CCNc1c2c(nc3ccccc13)CCCC2O -US20150087600A1,1,Brc1ncccn1.O=C(NC1CC(F)(F)C1)[C@H](c1ccccc1Cl)N(C(=O)[C@@H]1CCCN1)c1cccc(F)c1>>O=C(NC1CC(F)(F)C1)[C@H](c1ccccc1Cl)N(C(=O)[C@@H]1CCCN1c1ncccn1)c1cccc(F)c1 -US20100216810A1,2,Nc1nc2ccc(Oc3cccc(C(=O)Nc4cccc(C(F)(F)F)c4)c3)c([N+](=O)[O-])c2s1.O=C(Cl)C1CC1>>O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(Oc2ccc3nc(NC(=O)C4CC4)sc3c2[N+](=O)[O-])c1 -US05719140,10,Cc1nc(CCC(=O)O)cs1.O=C1CCC(=O)N1Br>>O=C(O)CCc1csc(CBr)n1 -US07459448B2,1,Brc1ccccc1.O=C1CCC(=O)c2ccc(Cl)cc2N1>>O=C1CCC(=O)N(c2ccccc2)c2cc(Cl)ccc21 -US20130022573A1,7,CC(=O)c1ccc2cnc(Cl)cc2c1>>C[C@@H](O)c1ccc2cnc(Cl)cc2c1 -US20070167449A1,4,COc1ccc(NC(N)=S)cc1.O=CCCl>>COc1ccc(Nc2nccs2)cc1 -US07704994B2,7,O=[N+]([O-])c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1>>Nc1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1 -US06476268B1,1,CC(N)c1ccccc1.COc1ccc(C=O)cc1>>COc1ccc(CNC(C)c2ccccc2)cc1 -US07544690B2,6,CN(C)c1nc(NC2CCN(Cc3ccccc3)CC2)nc2ccccc12>>CN(C)c1nc(NC2CCNCC2)nc2ccccc12 -US20060189625A1,6,COc1ccc(N2CCN(CCc3ccccc3)CC2)cc1>>Oc1ccc(N2CCN(CCc3ccccc3)CC2)cc1 -US20070265345A1,3,CC1(C)OB(c2ccc(NC(N)=O)cc2)OC1(C)C.FC(F)(F)C1(c2ccc(I)cc2)N=N1>>NC(=O)Nc1ccc(-c2ccc(C3(C(F)(F)F)N=N3)cc2)cc1 -US20130143858A1,2,C1CCNC1.CO[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CO[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCCC1 -US20090227560A1,1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn([C@@H]3CCCCC[C@H]3O)c2-c2ccccc2)[C@H](Cc2ccccc2)C1.COCCCBr>>COCCCO[C@@H]1CCCCC[C@H]1n1cnc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2Cc2ccccc2)c1-c1ccccc1 -US07572811B2,6,CC(C)(C)OC(=O)CCN1CCC(c2ccc(OCc3ccc(C4CCCCC4)c(C(F)(F)F)c3)cc2)CC1>>O=C(O)CCN1CCC(c2ccc(OCc3ccc(C4CCCCC4)c(C(F)(F)F)c3)cc2)CC1 -US04132710,10,CN1CC=C(c2ccccc2)CC1.O>>CN1CC[C@@H](c2ccccc2)[C@H](O)C1 -US05208247,2,CC(=O)NCc1ccccn1.CCCCCCCCCCCCCCOc1ccc(C(=O)Cl)cc1C(C)(C)C>>CCCCCCCCCCCCCCOc1ccc(C(=O)N(Cc2ccccn2)C(C)=O)cc1C(C)(C)C -US20130324579A1,6,CC(C)(C)OC(=O)NCCn1cc([N+](=O)[O-])cn1>>NCCn1cc([N+](=O)[O-])cn1 -US04275065,1,O=C(O)C(Br)c1ccccc1.Sc1nc2cccnc2s1>>O=C(O)C(Sc1nc2cccnc2s1)c1ccccc1 -US20100160309A1,1,CCCCOc1nccc2nc(OS(=O)(=O)C(F)(F)F)c3ccncc3c12.NCc1ccccc1>>CCCCOc1nccc2nc(NCc3ccccc3)c3ccncc3c12 -US08338426B2,2,CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(N)cc2F)CC1.O=C(O)c1ccccc1-c1cccnc1>>CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)c3ccccc3-c3cccnc3)cc2F)CC1 -US20110281873A1,3,CCCC[Sn](CCCC)(CCCC)c1c(C)noc1C.Clc1ncc(Br)c(Cl)n1>>Cc1noc(C)c1-c1nc(Cl)ncc1Br -US05798367,2,CC(C)n1nc(C(=O)NCCN2CCC(N)CC2)c2ccccc21.CCCCC(=O)Cl>>CCCCC(=O)NC1CCN(CCNC(=O)c2nn(C(C)C)c3ccccc23)CC1 -US20140288123A1,6,COC(=O)c1ccc(C(C)Oc2ccccc2)cc1F>>CC(Oc1ccccc1)c1ccc(C(=O)O)c(F)c1 -US20150111877A1,7,C=Cc1cccc(S(=O)(=O)N2C[C@H](C)Oc3ncc(NC(=O)OC(C)(C)C)cc32)c1>>CCc1cccc(S(=O)(=O)N2C[C@H](C)Oc3ncc(NC(=O)OC(C)(C)C)cc32)c1 -US20150225404A1,3,Cc1ncc(B2OC(C)(C)C(C)(C)O2)cn1.N#Cc1coc(COc2cc(Cl)c3c(n2)CCC3)n1>>Cc1ncc(-c2cc(OCc3nc(C#N)co3)nc3c2CCC3)cn1 -US06316445B1,2,O=C(Cl)Cc1ccc(Cl)c(Cl)c1.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(Cc1ccc(Cl)c(Cl)c1)N1C(=O)OC[C@@H]1Cc1ccccc1 -US20150045374A1,7,COc1ccc([N+](=O)[O-])cc1C>>COc1ccc(N)cc1C -US07217409B2,6,CCOC(=O)COCCOCCOCCOCCOCCOCCOCC(F)(F)F>>O=C(O)COCCOCCOCCOCCOCCOCCOCC(F)(F)F -US06946491B2,6,CCOC(=O)CCSCc1ccc(OCc2ccccc2F)cc1>>O=C(O)CCSCc1ccc(OCc2ccccc2F)cc1 -US20080280868A1,1,CC(C)c1cc(Cl)ncc1C(=O)NCC1CCC1.Cc1cccc(N)c1>>Cc1cccc(Nc2cc(C(C)C)c(C(=O)NCC3CCC3)cn2)c1 -US20120270795A1,6,COC(=O)[C@H](CCCC(N)C(=O)OC(C)(C)C)NNC(=O)c1cc(NC(=O)c2cc(NC(=O)c3cc([N+](=O)[O-])nn3Cc3ccc(OC)cc3)nn2Cc2ccc(OC)cc2)nn1Cc1ccc(OC)cc1>>COc1ccc(Cn2nc(NC(=O)c3cc(NC(=O)c4cc([N+](=O)[O-])nn4Cc4ccc(OC)cc4)nn3Cc3ccc(OC)cc3)cc2C(=O)NN[C@@H](CCCC(N)C(=O)OC(C)(C)C)C(=O)O)cc1 -US07351719B2,2,CCN(CC)CCOc1ccc(N)cc1OC.O=C(O)COc1ccc(C(F)(F)F)cc1Cl>>CCN(CC)CCOc1ccc(NC(=O)COc2ccc(C(F)(F)F)cc2Cl)cc1OC -US20100004490A1,1,FCOC(C(F)(F)F)C(F)(F)F.OC(C(F)(F)F)C(F)(F)F>>FC(F)(F)C(OCOC(C(F)(F)F)C(F)(F)F)C(F)(F)F -US03971819,7,COc1c([N+](=O)[O-])cc(C(=O)O)cc1S(N)(=O)=O>>COc1c(N)cc(C(=O)O)cc1S(N)(=O)=O -US08461175B2,9,CCS(=O)(=O)N1CCC(Nc2n[nH]c3c2nc(-c2c(F)cccc2F)c2cc(C=O)ccc23)CC1.NO>>CCS(=O)(=O)N1CCC(Nc2n[nH]c3c2nc(-c2c(F)cccc2F)c2cc(C=NO)ccc23)CC1 -US08080568B1,1,C1COCCN1.N#Cc1cc(CBr)cc([N+](=O)[O-])c1>>N#Cc1cc(CN2CCOCC2)cc([N+](=O)[O-])c1 -US04686227,4,Cc1nc2c3ccccc3ccn2c1CC#N.[N-]=[N+]=[N-]>>Cc1nc2c3ccccc3ccn2c1Cc1nnn[nH]1 -US20150057260A1,1,C1COCCN1.CCOC(=O)c1nc(Cl)ncc1F>>CCOC(=O)c1nc(Cl)ncc1N1CCOCC1 -US07361659B2,2,CC(CO)(CO)NS(=O)(=O)c1cc(N)c(Cl)s1.O=C(O)c1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12>>CC(CO)(CO)NS(=O)(=O)c1cc(NC(=O)c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)c(Cl)s1 -US20040102450A1,2,CCCC1NCCN(Cc2ccc3c(N)ncnc3c2)C1=O.O=C(O)COc1ccc(Cl)s1>>CCC[C@H]1C(=O)N(Cc2ccc3c(N)ncnc3c2)CCN1C(=O)COc1ccc(Cl)s1 -US20130310405A1,3,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c5cc(Br)ccc5nn4cc3-c3ccccc3)cc2)CCC1.N#Cc1cccc(B(O)O)c1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c5cc(-c6cccc(C#N)c6)ccc5nn4cc3-c3ccccc3)cc2)CCC1 -US04857659,7,CC1=CC(=O)OC1c1ccc(OCCCBr)cc1>>C[C@@H]1CC(=O)O[C@@H]1c1ccc(OCCCBr)cc1 -US20040209866A1,6,CCOC(=O)CSc1nc(C)cc2c1c(=O)cc(Nc1ccccc1)n2-c1ccccc1>>Cc1cc2c(c(SCC(=O)O)n1)c(=O)cc(Nc1ccccc1)n2-c1ccccc1 -US20030088103A1,1,O=[N+]([O-])c1ccccc1F.Oc1cncc(Cl)c1>>O=[N+]([O-])c1ccccc1Oc1cncc(Cl)c1 -US20120101100A1,3,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(B2OC(C)(C)C(C)(C)O2)cn1.FC(F)c1nnc(-c2cncc(Br)c2)[nH]1>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(-c3nnc(C(F)F)[nH]3)c2)cn1 -US06432981B1,3,CC(C)(C)OC(=O)N1CCC(CC=O)CC1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=CCC1CCN(C(=O)OC(C)(C)C)CC1 -US20150166483A1,2,COCCOCCOCCOc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(C(=O)O)c4OC)c4ccccc34)ccn2)cc(OC)c1.NC1COC1>>COCCOCCOCCOc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(C(=O)NC5COC5)c4OC)c4ccccc34)ccn2)cc(OC)c1 -US08163911B2,6,CCOP(=O)(CN(c1ccc2cc(NC(=O)OC(C)(C)C)ccc2c1)S(=O)(=O)c1cc(Cl)cc(Cl)c1)OCC>>CCOP(=O)(CN(c1ccc2cc(N)ccc2c1)S(=O)(=O)c1cc(Cl)cc(Cl)c1)OCC -US07276516B2,6,COC(=O)c1ccc(S(=O)(=O)n2cc(C3CCOCC3)c3ccccc32)cc1>>O=C(O)c1ccc(S(=O)(=O)n2cc(C3CCOCC3)c3ccccc32)cc1 -US20080200448A1,2,CC1CCC(CS(N)(=O)=O)CC1.CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCCC1=O>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)CC3CCC(C)CC3)CC2)nc1CN1CCCCC1=O -US20090012054A1,2,Nc1cnn2c1NCC2.O=C(O)CCNC(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C(CCNC(c1ccccc1)(c1ccccc1)c1ccccc1)Nc1cnn2c1NCC2 -US04888323,8,CC(C)(C)C1CCC(O)C(C(C)(C)C)C1>>CC(C)(C)C1CCC(=O)C(C(C)(C)C)C1 -US20050107372A1,4,O=C(CC(=O)C(F)(F)F)Nc1ccc2c(c1)NCCO2>>O=c1cc(C(F)(F)F)c2cc3c(cc2[nH]1)NCCO3 -US20140142085A1,2,COC(=O)Cc1c[nH]c2ccc(N)cc12.CS(=O)(=O)Cl>>COC(=O)Cc1c[nH]c2ccc(NS(C)(=O)=O)cc12 -US20130210796A1,2,CC(=O)OCC(=O)Cl.Cc1c(N)ccc(C#N)c1C(F)(F)F>>CC(=O)OCC(=O)Nc1ccc(C#N)c(C(F)(F)F)c1C -US05006651,6,CNC(=O)[C@H](CC(C)C)NC(=O)C(CC(C)C)CP(=O)(O)CN1C(=O)c2cccc(OCc3ccccc3)c2C1=O>>CNC(=O)[C@H](CC(C)C)NC(=O)C(CC(C)C)CP(=O)(O)CN1C(=O)c2cccc(O)c2C1=O -US08476297B2,2,Fc1cccc2c1CCNC2c1ccc(C(F)(F)F)cc1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)N1CCc2c(F)cccc2C1c1ccc(C(F)(F)F)cc1 -US20150133426A1,1,Clc1ncnc2[nH]c3c(c12)CCCC3.Nc1cc2sc(=O)[nH]c2cc1Cl>>O=c1[nH]c2cc(Cl)c(Nc3ncnc4[nH]c5c(c34)CCCC5)cc2s1 -US06518257B1,3,CC(C)C(O)(c1ccc(Br)cc1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.OB(O)c1ccc(Cl)cc1>>CC(C)C(O)(c1ccc(-c2ccc(Cl)cc2)cc1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1 -US06376669B1,9,CCOCc1nc2c(N)nc3ccccc3c2n1CCCl.[N-]=[N+]=[N-]>>CCOCc1nc2c(N)nc3ccccc3c2n1CCN=[N+]=[N-] -US20120053053A1,1,COC(=O)CO.CSc1nc(N)c(I)c(Cl)n1>>COC(=O)COc1nc(SC)nc(N)c1I -US20150164876A1,8,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(O)c3cccc(C(F)(F)F)c3)ccn2)c1>>CC(C)(C)OC(=O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)c3cccc(C(F)(F)F)c3)ccn2)c1 -US08513235B2,6,CC(C)N(CCCN1C(=O)c2ccccc2C1=O)S(=O)(=O)c1ccccc1[N+](=O)[O-]>>CC(C)N(CCCN)S(=O)(=O)c1ccccc1[N+](=O)[O-] -US08236837B2,2,CC(=O)OC(C)=O.COc1c(N)ccc2c1C(=CCN)CC2>>COc1c(N)ccc2c1C(=CCNC(C)=O)CC2 -US20110039852A1,1,CC=O.COC(=O)Cc1cccc(-c2c(CNCCCN3CCCC3=O)cccc2OC)c1>>CCN(CCCN1CCCC1=O)Cc1cccc(OC)c1-c1cccc(CC(=O)OC)c1 -US04176116,6,CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)OCc1ccccc1>>CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](C)N -US20140057902A1,2,COC(=O)C(C)C(=O)O.NCCc1ccccc1I>>COC(=O)C(C)C(=O)NCCc1ccccc1I -US20140329733A1,7,CCC=CCCC(O)C#CC(C)O>>CCC=CCCC(O)CCC(C)O -US20110263571A1,1,Cc1cnc(N2CCN(C(=O)c3ccc(Br)nc3)CC2)c(C2CC2)c1.O=C1NCCO1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4CCOC4=O)nc3)CC2)c(C2CC2)c1 -US20030195188A1,7,N#Cc1c(N)nc2c(c1-c1ccc(Cl)cc1Cl)CCc1ccccc1-2>>NCc1c(N)nc2c(c1-c1ccc(Cl)cc1Cl)CCc1ccccc1-2 -US20150056141A1,2,CC(=O)O.CCOC(=O)c1c(N)sc2c1CCCC2>>CCOC(=O)c1c(NC(C)=O)sc2c1CCCC2 -US07115749B2,6,CCOC(=O)c1cc(OCc2ccc(OC)cc2)n(CC(=O)N[C@H]2CCCC[C@@H]2OCc2ccccc2)n1>>CCOC(=O)c1cc(O)n(CC(=O)N[C@H]2CCCC[C@@H]2OCc2ccccc2)n1 -US09108983B2,6,CCOC(=O)CC(OCC)OCC>>CCOC(CC(=O)O)OCC -US05877317,1,C1CNCCN1.OCCC1OCCc2ccccc21>>c1ccc2c(c1)CCOC2CCN1CCNCC1 -US20070197512A1,6,COC(=O)CCN1C(=O)C(C(C)C)Oc2ccc(C(F)(F)F)cc21>>CC(C)C1Oc2ccc(C(F)(F)F)cc2N(CCC(=O)O)C1=O -US20130267482A1,2,CCOC(OCC)[C@H](C)N(Cc1csc2ccccc12)C(=O)[C@@H](N)CCCCNC(=O)OC(C)(C)C.CN(CC(=O)O)NC(=O)NCc1ccc(Cl)cc1>>CCOC(OCC)[C@H](C)N(Cc1csc2ccccc12)C(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)CN(C)NC(=O)NCc1ccc(Cl)cc1 -US05218115,1,ClCc1c[nH]cn1.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1ccc(-n2cnc(CCl)c2)c([N+](=O)[O-])c1 -US20080318999A1,1,COC1(OC)CCn2c(CCl)nc3cc(F)cc1c32.Fc1ccc(C2CCNCC2)cc1>>COC1(OC)CCn2c(CN3CCC(c4ccc(F)cc4)CC3)nc3cc(F)cc1c32 -US20150283262A1,6,C=CCOC(=O)N[C@H](C(=O)N[C@@H](C)C(=O)Nc1ccc(COC(=O)Nc2cc(O[Si](C(C)C)(C(C)C)C(C)C)c(OC)cc2C(=O)N2C=C(/C=C/C)C[C@H]2CO[Si](C)(C)C(C)(C)C)cc1)C(C)C>>C=CCOC(=O)N[C@H](C(=O)N[C@@H](C)C(=O)Nc1ccc(COC(=O)Nc2cc(O[Si](C(C)C)(C(C)C)C(C)C)c(OC)cc2C(=O)N2C=C(/C=C/C)C[C@H]2CO)cc1)C(C)C -US04785010,4,CC(=O)CCC(=O)CN1C(=O)c2ccccc2C1=O.NCCCn1ccnc1>>Cc1ccc(CN2C(=O)c3ccccc3C2=O)n1CCCn1ccnc1 -US08299085B2,1,CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc2c1=O.OC1CCNC1>>CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(N3CCC(O)C3)cc2c1=O -US05344843,1,COC(=O)C(=O)c1ccc(O)cc1.OCCOC1CCCCC1>>COC(=O)C(=O)c1ccc(OCCOC2CCCCC2)cc1 -US20080188528A1,9,CCOC(=O)c1ccc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)s1>>CCOC(=O)c1ccc(C(c2ccc(F)cc2)c2ccc(F)cc2)s1 -US07179823B1,1,CCOC(=O)CCc1cn(Cc2ccc3cc(O)ccc3c2)cc1-c1ccccc1.Cc1ncccc1CCl>>CCOC(=O)CCc1cn(Cc2ccc3cc(OCc4cccnc4C)ccc3c2)cc1-c1ccccc1 -US20150175599A1,1,CNC.COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cc3)c3ccc(C=O)cc23)ccn1>>COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cc3)c3ccc(CN(C)C)cc23)ccn1 -US05466692,1,C=C(OCC)c1c(C)nc(C)nc1Cl.NCc1ccc(Br)cc1>>C=C(OCC)c1c(C)nc(C)nc1NCc1ccc(Br)cc1 -US20110288066A1,3,CCCS(=O)(=O)c1cccc(C#Cc2cc(Br)ccc2OCC(=O)OC(C)(C)C)c1.Cc1nn(C)c(C)c1B(O)O>>CCCS(=O)(=O)c1cccc(C#Cc2cc(-c3c(C)nn(C)c3C)ccc2OCC(=O)OC(C)(C)C)c1 -US20090076070A1,9,N.O=C(O)c1ccc2[nH]nnc2c1>>NC(=O)c1ccc2[nH]nnc2c1 -US05789402,1,ClCCCCOc1cccc2[nH]ccc12.Clc1ccc2c(C3=CCNCC3)c[nH]c2c1>>Clc1ccc2c(C3=CCN(CCCCOc4cccc5[nH]ccc45)CC3)c[nH]c2c1 -US20130165446A1,1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CBr)cc1.CCCc1nc2c(C)cc(-c3nc4ccc(N(C)CCO)cc4n3C)cc2[nH]1>>CCCc1nc2c(C)cc(-c3nc4ccc(N(C)CCO)cc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1 -US07709479B1,3,CCCC[Sn](/C=C/CO)(CCCC)CCCC.COc1cc2c(SC)ncnc2cc1OS(=O)(=O)C(F)(F)F>>COc1cc2c(SC)ncnc2cc1C=CCO -US20080318943A1,3,CCCC[Sn](CCCC)(CCCC)c1ncccn1.Nc1c2c(nc3c(Br)cccc13)CN(C1CCC1)C2=O>>Nc1c2c(nc3c(-c4ncccn4)cccc13)CN(C1CCC1)C2=O -US04404230,6,COc1cccc2c1C(=O)NS2(=O)=O>>O=C1NS(=O)(=O)c2cccc(O)c21 -US20030130213A1,1,C[O-].N#Cc1nc(F)cnc1F>>COc1ncc(F)nc1C#N -US20120264711A1,2,CCOC(=O)C1CCC(CNCC(=O)OC(C)(C)C)N1C(=O)OC(C)(C)C.COC(=O)Cl>>CCOC(=O)C1CCC(CN(CC(=O)OC(C)(C)C)C(=O)OC)N1C(=O)OC(C)(C)C -US04453970,2,COC(=O)Nc1nc(C)cc(OC)n1.NS(=O)(=O)c1cccc2cccnc12>>COc1cc(C)nc(NC(=O)NS(=O)(=O)c2cccc3cccnc23)n1 -US20070197620A1,2,CON(C)C(=O)C1CCNc2ccccc21.Cc1ccc(S(=O)(=O)Cl)cc1>>CON(C)C(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)c2ccccc21 -US06967198B2,6,CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)C1CCCCC1>>N[C@H](C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)C1CCCCC1 -US07402642B2,6,CC(C)(C)OC(=O)C1CCC=CCCC1>>O=C(O)C1CCC=CCCC1 -US20080214545A1,1,CC(C)(C)c1cc(N)n(-c2cccc(O)c2)n1.OCCCCl>>CC(C)(C)c1cc(N)n(-c2cccc(OCCCO)c2)n1 -US20090093454A1,1,CN(C)[C@H]1CCNC1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>CN(C)[C@H]1CCN(c2cccc3nc(CN4CCC[C@H]5CCc6cccnc6[C@H]54)cn23)C1 -US20150051230A1,9,CC(=O)OC[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](c2c[nH]c3c(N=[N+]=[N-])ncnc23)N1C(=O)OC(C)(C)C>>CC(=O)OC[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](c2c[nH]c3c(N)ncnc23)N1C(=O)OC(C)(C)C -US20110065702A1,3,O=C1Cc2ccccc2N1.O=Cc1ccc2c(/C=C/c3ccccc3)n[nH]c2c1>>O=C1Nc2ccccc2/C1=C\c1ccc2c(/C=C/c3ccccc3)n[nH]c2c1 -US20130082209A1,4,CC(C)(C)c1cccc(C(=O)O)c1N.NC=O>>CC(C)(C)c1cccc2c(=O)[nH]cnc12 -US20150119362A1,7,COC(=O)Cc1ccc(Cc2cc(C(F)(F)F)nc(OC3CCCC3)n2)cc1>>OCCc1ccc(Cc2cc(C(F)(F)F)nc(OC3CCCC3)n2)cc1 -US20140336177A1,1,CC(C)(C)OC(=O)N1CCN[C@H](CO)C1.N#Cc1cc(C(=O)CBr)ccc1F>>CC(C)(C)OC(=O)N1CCN(CC(=O)c2ccc(F)c(C#N)c2)[C@H](CO)C1 -US20080076771A1,2,Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1.O=C(Cl)c1ccc(Nc2cncnc2)cc1>>O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cncnc2)cc1 -US04333940,2,CCCCCCCCCCCCCCCC(=O)Cl.CCOC(=O)c1ccc(N)c(F)c1>>CCCCCCCCCCCCCCCC(=O)Nc1ccc(C(=O)OCC)cc1F -US20140179638A1,6,O=C(NCC1CCC2(CC1)CC2)OCc1ccccc1>>NCC1CCC2(CC1)CC2 -US08598355B2,7,O=C1OC(=Cc2cc(Cl)ccc2[N+](=O)[O-])c2ccccc21>>Nc1ccc(Cl)cc1C=C1OC(=O)c2ccccc21 -US20120184542A1,6,COC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(OC)nc3[nH]c2=O)c1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1 -US20090247559A1,1,CC(Cl)c1ccc(O)c(C#N)c1.NC(=O)CBr>>CC(Cl)c1ccc(OCC(N)=O)c(C#N)c1 -US20110301353A1,3,CCN(CC)CCN1CCc2[nH]c(C=O)c(C)c2C1=O.COc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1>>CCN(CC)CCN1CCc2[nH]c(C=C3C(=O)Nc4ccc(-c5ccc(OC)cc5)cc43)c(C)c2C1=O -US20100292188A1,6,CCOC(=O)C1Cc2nc(-c3ccc(O[C@@H]4C[C@@H](N5CCCCC5)C4)cc3)sc2C1>>O=C(O)C1Cc2nc(-c3ccc(OC4CC(N5CCCCC5)C4)cc3)sc2C1 -US20150087637A1,9,C=CCCOCC=O.NO>>C=CCCOCC=NO -US05114960,6,COC(=O)C1(C)CCc2onc(-c3ccc(Cl)cc3)c2CC1>>CC1(C(=O)O)CCc2onc(-c3ccc(Cl)cc3)c2CC1 -US20100016337A1,7,O=[N+]([O-])c1ccc(-c2ccccc2F)nc1>>Nc1ccc(-c2ccccc2F)nc1 -US20130040930A1,1,CN1CCNC1=O.Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2cnc(Br)cn2)CC1>>Cc1cc(C2CC2)cnc1N1CCN(C(=O)c2cnc(N3CCN(C)C3=O)cn2)CC1 -US05541195,2,O=C(Cl)Cc1ccccc1.O=C(N(Cc1ccnc2ccccc12)[C@H]1CCN[C@H](Cc2ccccc2)C1)C(F)(F)F>>O=C(Cc1ccccc1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1 -US20040242884A1,1,CN.OC(CCl)c1ncccn1>>CNCC(O)c1ncccn1 -US06184236B2,7,CC(=O)N(CCCc1ccccc1)[C@@H]1CC[C@@H](c2ccc(OCc3ccccc3)cc2)CC1>>CCN(CCCc1ccccc1)[C@@H]1CC[C@@H](c2ccc(OCc3ccccc3)cc2)CC1 -US20140179733A1,7,O=[N+]([O-])c1cnn(-c2ccc(F)cc2)c1>>Nc1cnn(-c2ccc(F)cc2)c1 -US20110130407A1,6,Cc1c(C(=O)OCc2ccccc2)c2cccc(F)c2c(=O)n1-c1cccnc1>>Cc1c(C(=O)O)c2cccc(F)c2c(=O)n1-c1cccnc1 -US09133181B2,2,COCC(=O)Cl.Cc1n[nH]c2nc(-c3ccc(O)cc3)cc(CN3CC4(CCCC4)NCC3C)c12>>COCC(=O)N1CC(C)N(Cc2cc(-c3ccc(O)cc3)nc3[nH]nc(C)c23)CC12CCCC2 -US20130030031A1,1,CN(C)C(=O)CCl.COC(=O)c1ccc(O)c(OC)c1>>COC(=O)c1ccc(OCC(=O)N(C)C)c(OC)c1 -US07595397B2,2,CC(=O)Cl.Cc1ccc(Cl)c(-c2ccc(CN3CCN[C@@H](Cc4ccccc4)C3)cc2)c1>>CC(=O)N1CCN(Cc2ccc(-c3cc(C)ccc3Cl)cc2)C[C@@H]1Cc1ccccc1 -US20070197604A1,3,COc1ccc(B(O)O)cc1.Cc1oc(-c2ccc(Br)cc2)nc1CCN1CCC[C@H]1C>>COc1ccc(-c2ccc(-c3nc(CCN4CCC[C@H]4C)c(C)o3)cc2)cc1 -US20070135442A1,1,CCN1CCNCC1.CCOC(=O)c1cc(=O)c2cc(OC)cc(Br)c2o1>>CCOC(=O)c1cc(=O)c2cc(OC)cc(N3CCN(CC)CC3)c2o1 -US20150025068A1,2,CC(C)O.COC(=O)c1ccc(NS(=O)(=O)c2cc(-c3cccc(C(=O)O)c3)c(Cl)s2)cc1O>>COC(=O)c1ccc(NS(=O)(=O)c2cc(-c3cccc(C(=O)OC(C)C)c3)c(Cl)s2)cc1O -US07247625B2,1,CCC1(CC)OC(=O)N(C)c2ccc(N)cc21.Clc1cccc(I)c1Cl>>CCC1(CC)OC(=O)N(C)c2ccc(Nc3cccc(Cl)c3Cl)cc21 -US20060035922A1,1,BrCc1ccccc1.Cc1cc(O)cc(Br)c1>>Cc1cc(Br)cc(OCc2ccccc2)c1 -US20150133425A1,1,CC(C)NC(=O)C1CCc2c(sc3ncnc(Cl)c23)C1.COc1cc2[nH]ncc2cc1N>>COc1cc2[nH]ncc2cc1Nc1ncnc2sc3c(c12)CCC(C(=O)NC(C)C)C3 -US04694017,2,CCOC(=O)c1ccc(Cl)cc1.NC(CC1C(=O)Nc2ccccc21)C(=O)O>>O=C(NC(CC1C(=O)Nc2ccccc21)C(=O)O)c1ccc(Cl)cc1 -US04051260,6,CCOC(=O)Cc1ccc2c(=O)c3ccccc3ccc2c1>>O=C(O)Cc1ccc2c(=O)c3ccccc3ccc2c1 -US05420126,7,O=[N+]([O-])c1cc(S(=O)(=O)c2ccccc2)ccc1O>>Nc1cc(S(=O)(=O)c2ccccc2)ccc1O -US20110130398A1,6,CNc1cc(C(=O)OC)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F>>CNc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F -US08216974B2,9,COC(=O)C(F)(c1ccc(C(F)(F)F)cc1)S(=O)(=O)CCC(F)(F)F.N>>NC(=O)C(F)(c1ccc(C(F)(F)F)cc1)S(=O)(=O)CCC(F)(F)F -US05616537,1,COC(=O)c1c(O)ccc2ocnc12.COc1cc(OC)nc(Cl)n1>>COC(=O)c1c(Oc2nc(OC)cc(OC)n2)ccc2ocnc12 -US05409956,3,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc2c(c1)CC(CNS(=O)(=O)c1ccc(Cl)cc1)C2>>CCOC(=O)/C=C/c1ccc2c(c1)CC(CNS(=O)(=O)c1ccc(Cl)cc1)C2 -US04144341,1,Cc1c(N)cccc1Cl.O=[N+]([O-])c1cccnc1Cl>>Cc1c(Cl)cccc1Nc1ncccc1[N+](=O)[O-] -US20100113776A1,1,Ic1ccc(OC2CCN(C3CCC3)CC2)cc1.O=[N+]([O-])c1cn[nH]c1>>O=[N+]([O-])c1cnn(-c2ccc(OC3CCN(C4CCC4)CC3)cc2)c1 -US20110009454A1,2,Cc1ccc(Oc2ccc(CN)cc2)cc1.Nc1nc(F)ccc1C(=O)O>>Cc1ccc(Oc2ccc(CNC(=O)c3ccc(F)nc3N)cc2)cc1 -US06245761B1,1,COCCO.Fc1ccc(Br)cc1CBr>>COCCOCc1cc(Br)ccc1F -USRE045183E1,2,CC1CCC(N(C(=O)Nc2ncc(CN3CCN(S(=O)(=O)N(C)C)CC3)s2)C2CCNCC2)CC1.O=C(Cl)C1CCCC1>>CC1CCC(N(C(=O)Nc2ncc(CN3CCN(S(=O)(=O)N(C)C)CC3)s2)C2CCN(C(=O)C3CCCC3)CC2)CC1 -US20060211695A1,2,CCNC(=O)Oc1cn2ncnc(Oc3ccc(N)cc3F)c2c1C.O=C=NC(=O)Cc1ccc(F)cc1>>CCNC(=O)Oc1cn2ncnc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c2c1C -US08084448B2,3,C=CCc1ccccc1.C[Si](C)(C)CCN1C(=O)CN(c2ccc(I)cc2OCc2ccccc2)S1(=O)=O>>C[Si](C)(C)CCN1C(=O)CN(c2ccc(/C=C/Cc3ccccc3)cc2OCc2ccccc2)S1(=O)=O -US20050065118A1,1,C=[N+]=[N-].O=C(O)CCc1cccc(O)c1>>COC(=O)CCc1cccc(O)c1 -US20030195230A1,1,CN1CCC(O)CC1.COc1ccc(NC(=O)c2cccnc2Nc2ccc3cn[nH]c3c2)cc1O>>COc1ccc(NC(=O)c2cccnc2Nc2ccc3cn[nH]c3c2)cc1OC1CCN(C)CC1 -US20090227560A1,1,CCOP(OCC)OCC.FC(F)(F)Oc1ccccc1CBr>>CCOP(=O)(Cc1ccccc1OC(F)(F)F)OCC -US05981521,3,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.N#CCCC(CC=O)(c1ccccc1)c1ccccc1>>COC(=O)C=CCC(CCC#N)(c1ccccc1)c1ccccc1 -US09108981B2,6,C=C[C@@H](NC(=O)OC(C)(C)C)c1cccc(Cl)c1F>>C=C[C@@H](N)c1cccc(Cl)c1F -US20060058553A1,7,O=Cc1cc(Br)cc([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(Br)cc(CO)c1 -US08410107B2,2,COc1cncc(C(=O)O)c1.Nc1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1>>COc1cncc(C(=O)Nc2cnc(OCC(F)(F)F)c(-c3ccc(Cl)cc3)c2)c1 -US20060183909A1,6,COC(=O)c1cc(O)c2c(-c3ccccc3)ccc(OCc3ccccc3)c2n1>>COC(=O)c1cc(O)c2c(-c3ccccc3)ccc(O)c2n1 -US05478825,1,CN(C)c1nc2nc3c(c(Cl)n2n1)SCCC3.NCCN1CCOCC1>>CN(C)c1nc2nc3c(c(NCCN4CCOCC4)n2n1)SCCC3 -US20100267723A1,1,C[C@H]1COC[C@H](C)N1Cc1cc(F)c(Cl)cc1F.Cc1ncc(-c2nc(N)ncc2F)n1C1CCOCC1>>Cc1ncc(-c2nc(Nc3cc(F)c(CN4[C@@H](C)COC[C@@H]4C)cc3F)ncc2F)n1C1CCOCC1 -US20100004280A1,3,CC1(C)OB(c2ccc3c(c2)CCC3(O)Cc2nc(CC3(C(F)(F)F)CC3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)OC1(C)C.Fc1ccc(Br)nc1>>OC1(Cc2nc(CC3(C(F)(F)F)CC3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)CCc2cc(-c3ccc(F)cn3)ccc21 -US20100041892A1,1,CCOC(=O)c1cc(C(C)(C)C)n[nH]1.FC(F)(F)c1ccc(CCl)c(Cl)c1>>CCOC(=O)c1cc(C(C)(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl -US05470967,9,C[SiH](C)[C@]1(n2cnc3c(NC(=O)c4ccccc4)ncnc32)C[C@H](OC(C)(C)C)[C@@H](CN=[N+]=[N-])O1>>C[SiH](C)[C@]1(n2cnc3c(NC(=O)c4ccccc4)ncnc32)C[C@H](OC(C)(C)C)[C@@H](CN)O1 -US20130158066A1,4,Nc1ccc(Br)nc1C#Cc1ccccc1Cl>>Clc1ccccc1-c1cc2nc(Br)ccc2[nH]1 -US05208247,1,CCCCCCCCCCCCCCOc1ccc(N)cc1.O=Cc1cccnc1>>CCCCCCCCCCCCCCOc1ccc(NCc2cccnc2)cc1 -US20040082661A1,1,CCNc1ccc(C)c(F)c1.NCCBr>>CCN(CCN)c1ccc(C)c(F)c1 -US20090131468A1,3,CC(C)OB(C#CC(C)(C)C)OC(C)C.NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)nc1>>CC(C)(C)C#Cc1ccc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)cn1 -US06770646B2,6,COC(=O)CCCSc1c2c(=O)n(C)nc(CC(C)C)c2cn1Cc1cccc2ccccc12>>CC(C)Cc1nn(C)c(=O)c2c(SCCCC(=O)O)n(Cc3cccc4ccccc34)cc12 -US05132325,2,Nc1cc(Cl)c(OCC(F)(F)F)cc1F.O=C=NC(=O)c1c(F)cccc1F>>O=C(NC(=O)c1c(F)cccc1F)Nc1cc(Cl)c(OCC(F)(F)F)cc1F -US07034045B1,3,CN(C)S(=O)(=O)NCC(C)(F)c1ccc(I)cc1.Nc1cccc(B(O)O)c1>>CN(C)S(=O)(=O)NCC(C)(F)c1ccc(-c2cccc(N)c2)cc1 -US07326716B2,3,COP(=O)(CC(=O)Cc1ccccc1)OC.N#CCOCC#CCN1C(=O)CCC[C@@H]1C=O>>N#CCOCC#CCN1C(=O)CCC[C@@H]1/C=C/C(=O)Cc1ccccc1 -US20140213578A1,2,NCC(O)CN1c2ccccc2CCc2ccc(Cl)cc21.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>O=S(=O)(NCC(O)CN1c2ccccc2CCc2ccc(Cl)cc21)c1ccc(OC(F)(F)F)cc1 -US05696110,7,Cn1nnnc1-c1cccc([N+](=O)[O-])c1>>Cn1nnnc1-c1cccc(N)c1 -US05935959,6,CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)N1CCN(c2ccc(F)cc2)CC1>>NC(Cc1ccccc1)C(=O)N1CCN(c2ccc(F)cc2)CC1 -US20150210688A1,2,COCc1nc(Cl)c(-c2cc(C(=O)O)ccc2C)[nH]1.N#Cc1ccc(C2CCNCC2)cc1>>COCc1nc(Cl)c(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)ccc2C)[nH]1 -US20060173018A1,6,COc1ccccc1-c1nc(Cl)c2cc(Br)ccc2n1>>Oc1ccccc1-c1nc(Cl)c2cc(Br)ccc2n1 -US20100016340A1,1,Clc1ncnc2[nH]ccc12.NC1(C(=O)NCc2ccc(Cl)c(-c3ccccc3)c2)CCNCC1>>NC1(C(=O)NCc2ccc(Cl)c(-c3ccccc3)c2)CCN(c2ncnc3[nH]ccc23)CC1 -US20150105367A1,1,CC(N)=O.Cc1nc2cc(Cl)ncc2cc1-c1cc(NC(=O)OC(C)(C)C)c(F)cc1F>>CC(=O)Nc1cc2nc(C)c(-c3cc(NC(=O)OC(C)(C)C)c(F)cc3F)cc2cn1 -US20100210704A1,8,CC(=O)Nc1cc(OC(F)(F)C(F)F)nn1-c1cc(SCC(F)(F)F)c(C)cc1F.O=C(OO)c1cccc(Cl)c1>>CC(=O)Nc1cc(OC(F)(F)C(F)F)nn1-c1cc(S(=O)CC(F)(F)F)c(C)cc1F -US20120015908A1,6,O=C1CC(c2ccccc2OCc2ccccc2)=Nc2ccc(N3CCOCC3)cc21>>O=C1CC(c2ccccc2O)=Nc2ccc(N3CCOCC3)cc21 -US20140112945A1,6,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4cn(C)c5ccccc45)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4cn(C)c5ccccc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US04699905,6,CC(C)(C)OC(=O)CN1CC(c2cccs2)SCC(N2C(=O)c3ccccc3C2=O)C1=O>>CC(C)(C)OC(=O)CN1CC(c2cccs2)SCC(N)C1=O -US05747499,1,Cc1nc2cc3c(cc2c(=O)n1COC(=O)C(C)(C)C)C(Br)CC3.Nc1ccc(C(=O)O)c(F)c1>>Cc1nc2cc3c(cc2c(=O)n1COC(=O)C(C)(C)C)C(Nc1ccc(C(=O)O)c(F)c1)CC3 -US07799947B2,6,COc1cc(Cl)cc(CN)c1>>NCc1cc(O)cc(Cl)c1 -US20090275578A1,9,Cc1cc(Br)cc2c1C(=O)N(Cc1ccc(Cl)cc1)C2.[C-]#N>>Cc1cc(C#N)cc2c1C(=O)N(Cc1ccc(Cl)cc1)C2 -US05994555,9,O=C(Cl)[C@H](Cc1ccccc1)N1C(=O)c2ccccc2C1=O>>O=C[C@H](Cc1ccccc1)N1C(=O)c2ccccc2C1=O -US20150191464A1,1,CCOC(=O)c1cnc(Cl)cc1Cl.Nc1cnn(CC(F)F)c1>>CCOC(=O)c1cnc(Cl)cc1Nc1cnn(CC(F)F)c1 -US20060183754A1,2,CCOC(=O)C(C)(C)Oc1ccc(OCCN)cc1C.O=C(O)Cc1cnc(-c2ccc(C(F)(F)F)cc2)nc1C1CC1>>CCOC(=O)C(C)(C)Oc1ccc(OCCNC(=O)Cc2cnc(-c3ccc(C(F)(F)F)cc3)nc2C2CC2)cc1C -US20070265269A1,2,C#CCO.O=C(O)C1CCCCC1>>C#CCOC(=O)C1CCCCC1 -US05523456,6,CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12)NC(=O)CCCc1ccc([N+](=O)[O-])cc1>>CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)O)Cc1cccc2ccccc12)NC(=O)CCCc1ccc([N+](=O)[O-])cc1 -US20020156081A1,3,CN1CCN([C@@H]2CC[C@H](n3nc(I)c4c(N)ncnc43)CC2)CC1.O=C(NCCc1ccccc1)c1ccc(B(O)O)cc1>>CN1CCN([C@@H]2CC[C@H](n3nc(-c4ccc(C(=O)NCCc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 -US20070155803A1,6,CC(C)(C)OC(=O)NN1CC[C@H](NC(=O)OCc2ccccc2)C1=O>>NN1CC[C@H](NC(=O)OCc2ccccc2)C1=O -US04051260,6,CCC(C(=O)OC)c1ccc2c(=O)c3ccccc3ccc2c1>>CCC(C(=O)O)c1ccc2c(=O)c3ccccc3ccc2c1 -US20090227620A1,6,CCOC(=O)C1(C2CCN(C(=O)OC(C)(C)C)CC2)CCCC1>>CC(C)(C)OC(=O)N1CCC(C2(C(=O)O)CCCC2)CC1 -US20140194412A1,1,O=Cc1ccccc1O.O=[N+]([O-])c1ccc(OCCBr)cc1>>O=Cc1ccccc1OCCOc1ccc([N+](=O)[O-])cc1 -US20050233981A1,2,CC(C)(C/C=C/C(=O)O)NC(=O)OC(C)(C)C.CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)N1CCC(CN(C)C)CC1>>CN(C)CC1CCN(C(=O)[C@@H](Cc2ccccc2)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)/C=C/CC(C)(C)NC(=O)OC(C)(C)C)CC1 -US20080153873A1,1,CC1(C)C(=O)N(C(c2ccc(F)cc2F)C(O)CO)c2ccccc21>>CC1(C)C(=O)N(C2c3ccc(F)cc3OC2CO)c2ccccc21 -US20060074102A1,9,COC(=O)c1cc2c(Br)c(Cl)ncc2s1>>COC(=O)c1cc2cc(Cl)ncc2s1 -US20080269210A1,3,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.Clc1nc(N2CCOCC2)c2sc(I)cc2n1>>Nc1ccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)cc1 -US20070213348A1,3,CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(Br)cc2)CC(C)(C)C1.OB(O)c1ccoc1>>CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(-c3ccoc3)cc2)CC(C)(C)C1 -US20090018134A1,2,C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)cn3)CC2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C2(S(=O)(=O)c3ccc(F)cn3)CC2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1 -US20030119748A1,2,C[C@H](N)C(=O)N[C@H](C=O)CC(=NNC(N)=O)OC(C)(C)C.Cn1c(C(=O)O)cc2ccccc21>>C[C@H](NC(=O)c1cc2ccccc2n1C)C(=O)N[C@H](C=O)CC(=NNC(N)=O)OC(C)(C)C -US06878750B2,1,CC(C)(C)c1ccc(S)cc1.ICCCCCOc1ccc(C2=C(c3ccccc3)CCCc3cc(OC4CCCCO4)ccc32)cc1>>CC(C)(C)c1ccc(SCCCCCOc2ccc(C3=C(c4ccccc4)CCCc4cc(OC5CCCCO5)ccc43)cc2)cc1 -US20090325956A1,1,FCCCCBr.O=[N+]([O-])c1cn[nH]c1>>O=[N+]([O-])c1cnn(CCCCF)c1 -US08618094B2,6,CC(C)(C)OC(=O)N[C@@]12CC(CF)[C@@H]1CN(C(=O)OCc1ccccc1)C2>>CC(C)(C)OC(=O)N[C@]12CNC[C@H]1C(CF)C2 -US20100119503A1,1,CC1COCCC1=O.N[C@@H]1CC[C@@](C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)([C@H]2CCOC2)C1>>CC1COCC[C@H]1N[C@@H]1CC[C@@](C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)([C@H]2CCOC2)C1 -US20070111988A1,3,CC1(C)OB(c2ccc3c(c2)CNC3=O)OC1(C)C.COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(Br)sc2c1>>COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc4c(c3)CNC4=O)sc2c1 -US06194406B1,2,CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCNC3)CC2)nc2ccccc21.COc1ccc(CSC)cc1C(=O)O>>CCOCCn1c(N2CCCN(CCC3(c4ccccc4)CCN(C(=O)c4cc(CSC)ccc4OC)C3)CC2)nc2ccccc21 -US05495023,8,CCC(=CC(CNC(=O)c1cccnc1)=NO)C(C)[N+](=O)[O-].O=C(OO)c1cccc(Cl)c1>>CCC(=CC(CNC(=O)c1ccc[n+]([O-])c1)=NO)C(C)[N+](=O)[O-] -US06069132,1,CCCCCCBr.Nc1ncnc2pc[nH]c12>>CCCCCCn1cpc2ncnc(N)c21 -US20090029994A1,1,CCI.O=C(Nc1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(Br)cn1)OCc1ccccc1>>CCN(C(=O)OCc1ccccc1)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(Br)cn1 -US20140155389A1,1,CC(C)(C)OC(=O)N1CCNCC1.COc1cc(F)ccc1[N+](=O)[O-]>>COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-] -US20090137584A1,2,CC(=O)Cl.CC(C)(C)Cc1nc2cc(S(=O)(=O)C(C)(C)CN)ccc2n1CC1CC1>>CC(=O)NCC(C)(C)S(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CC1 -US06919349B2,6,COC(=O)C(CNC(=O)N1CCC2(CC1)C(=O)N(C)CN2c1ccccc1)NCc1c(Cl)cccc1Cl>>CN1CN(c2ccccc2)C2(CCN(C(=O)NCC(NCc3c(Cl)cccc3Cl)C(=O)O)CC2)C1=O -US20130096118A1,1,Cc1c(N)cccc1-c1cnc(C(N)=O)c2[nH]c3cc(NC(=O)OCC[Si](C)(C)C)ccc3c12.O=Cc1ccc(Cl)cc1C(=O)O>>Cc1c(NCc2ccc(Cl)cc2C(=O)O)cccc1-c1cnc(C(N)=O)c2[nH]c3cc(NC(=O)OCC[Si](C)(C)C)ccc3c12 -US20050096337A1,1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.COCc1nc(-c2ccc(OC(F)(F)F)cc2)ncc1CCl>>CCOC(=O)C(C)(C)Oc1ccc(OCc2cnc(-c3ccc(OC(F)(F)F)cc3)nc2COC)cc1C -US07179912B2,1,C1COCCN1.NC(=O)c1cc(Cl)ccc1[N+](=O)[O-]>>NC(=O)c1cc(N2CCOCC2)ccc1[N+](=O)[O-] -US08063071B2,1,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(C=O)c4)cc23)CC1.NCc1ccsc1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CNCc5ccsc5)c4)cc23)CC1 -US09051340B2,9,C[C@H]1CC[C@@H](c2nc(I)c(I)[nH]2)N1C(=O)OC(C)(C)C>>C[C@H]1CC[C@@H](c2ncc(I)[nH]2)N1C(=O)OC(C)(C)C -US20120220635A1,2,C=CCN(CCc1ccc(N)cc1)C(=O)OC(C)(C)C.CC(C)c1ccc(S(=O)(=O)Cl)cc1>>C=CCN(CCc1ccc(NS(=O)(=O)c2ccc(C(C)C)cc2)cc1)C(=O)OC(C)(C)C -US04341957,7,CC(=O)c1ccc(C#N)s1>>CC(=O)c1ccc(CN)s1 -US20120129870A1,7,N#Cc1cc([N+](=O)[O-])ccc1N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1>>N#Cc1cc(N)ccc1N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 -US20120178736A1,1,Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(Cl)nc21.c1ccc2[nH]c(C3CCCO3)nc2c1>>Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(-n3c([C@@H]4CCCO4)nc4ccccc43)nc21 -US09073947B2,2,C=CC(=O)O.Nc1cccc(Oc2ncnc(N)c2-c2ccc(Oc3ccccc3)cc2)c1>>C=CC(=O)Nc1cccc(Oc2ncnc(N)c2-c2ccc(Oc3ccccc3)cc2)c1 -US20120094964A1,1,COC(=O)c1ccc(S(=O)(=O)Nc2ncc(C(F)(F)F)cc2Cl)cc1.N#CC1(c2ccc(CBr)cc2)CC1>>COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(C3(C#N)CC3)cc2)c2ncc(C(F)(F)F)cc2Cl)cc1 -US20090247526A1,1,Cc1csc(N)n1.Clc1cc(Oc2ccccc2)ncn1>>Cc1csc(Nc2cc(Oc3ccccc3)ncn2)n1 -US08143424B2,1,CI.O=Cc1ccc2c(c1O)CCC2>>COc1c(C=O)ccc2c1CCC2 -US20040192680A1,3,CCOP(=O)(CC(=O)NC1CCC(O)CC1)OCC.O=Cc1cccnc1Sc1ccc(Br)cc1>>O=C(/C=C/c1cccnc1Sc1ccc(Br)cc1)NC1CCC(O)CC1 -US20120270838A1,1,CCOC(=O)C(C)Br.Cc1cc(N)ccc1Br>>CCOC(=O)C(C)Nc1ccc(Br)c(C)c1 -US20140128429A1,8,CCn1cncc1C(O)c1cccc(C#N)c1>>CCn1cncc1C(=O)c1cccc(C#N)c1 -US20130161593A1,3,Nc1ccc(Br)cc1.OB(O)c1cccc2ccccc12>>Nc1ccc(-c2cccc3ccccc23)cc1 -US20140199263A1,3,Brc1cncc(-c2cn3ccccc3n2)c1.CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(B3OC(C)(C)C(C)(C)O3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cncc(-c4cn5ccccc5n4)c3)cc12 -US08492540B2,1,CC(C)(C)c1nc(C2CCC2)cc(N2CCNCC2)n1.O=c1cnn(CCCCCl)c(=O)[nH]1>>CC(C)(C)c1nc(C2CCC2)cc(N2CCN(CCCCn3ncc(=O)[nH]c3=O)CC2)n1 -US20150018373A1,4,CCOC(=O)C(N)=S.O=C(CBr)C(F)(F)F>>CCOC(=O)c1nc(C(F)(F)F)cs1 -US20090012055A1,1,COCCCN1C(=O)CSc2ccc(CCl)cc21.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1>>COCCCN1C(=O)CSc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCCOCc4ccccc4OC)cc3)cc21 -US04119710,7,CCC(C)(C)NCC(=O)c1cc(F)c(N)c(C#N)c1>>CCC(C)(C)NCC(O)c1cc(F)c(N)c(C#N)c1 -US08334287B2,3,C#Cc1cccc(Cl)c1.COCCn1ncc(-n2cc(I)nc2C)cc1=O>>COCCn1ncc(-n2cc(C#Cc3cccc(Cl)c3)nc2C)cc1=O -US20060116410A1,6,COC(=O)c1cc(Cl)cc(N(Cc2ccccc2)C(C)C)c1>>CC(C)N(Cc1ccccc1)c1cc(Cl)cc(C(=O)O)c1 -US07612094B2,3,CN(C)C=O.Ic1ccc2ncnn2c1>>O=Cc1ccc2ncnn2c1 -US20140112945A1,2,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)[C@H](C)c4ccccc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cc1[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc2c1C(=O)O>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](NC(=O)c4c(C)[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)[C@H](C)c4ccccc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC -US05162349,1,Cc1nnc(-c2nnc(S)o2)o1.FC(F)=C(F)CCBr>>Cc1nnc(-c2nnc(SCCC(F)=C(F)F)o2)o1 -US20090209522A1,1,CC(C)(C)c1ccc(C#N)c(O)c1.COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Br)n1>>COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Oc2cc(C(C)(C)C)ccc2C#N)n1 -US07572809B2,3,COc1ccc2cc(Nc3cc(C)[nH]n3)nc(Cl)c2c1.OB(O)c1ccccc1F>>COc1ccc2cc(Nc3cc(C)[nH]n3)nc(-c3ccccc3F)c2c1 -US07557213B2,3,CCOc1ccc(I)cc1C.CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O>>CCOc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1C -US20100094000A1,6,Cc1nn(CCCCCOCc2ccccc2)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2>>Cc1nn(CCCCCO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 -US20110237581A1,1,NC1CC1.O=Cc1cccc(C2c3n[nH]c(=O)c4cccc(c34)NC2c2ccccc2)c1>>O=c1[nH]nc2c3c(cccc13)NC(c1ccccc1)C2c1cccc(CNC2CC2)c1 -US07015218B1,2,Cc1c(C(=O)Cl)cnn1-c1ccc(Cl)cc1.N#Cc1cc(N2CCC(N3CCOCC3)CC2)ccc1N>>Cc1c(C(=O)Nc2ccc(N3CCC(N4CCOCC4)CC3)cc2C#N)cnn1-c1ccc(Cl)cc1 -US20080146565A1,1,Fc1cnc(Cl)nc1Cl.c1ccc2[nH]ccc2c1>>Fc1cnc(Cl)nc1-n1ccc2ccccc21 -US07932272B2,2,NCc1ccc(Oc2ccccc2)s1.Nc1nc2c(cc1C(=O)O)CCC2>>Nc1nc2c(cc1C(=O)NCc1ccc(Oc3ccccc3)s1)CCC2 -US20090076070A1,7,CC(Oc1ccc(-c2nc(-c3cccc4[nH]ccc34)no2)cc1C(F)(F)F)C(F)(F)F>>CC(Oc1ccc(-c2nc(-c3cccc4c3CCN4)no2)cc1C(F)(F)F)C(F)(F)F -US08344023B2,3,CC(=O)OCCC(C)CC=O.CCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCC/C=C\CC(C)CCOC(C)=O -US07192943B2,2,CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O.Cn1ncc(N)c1N>>Cn1ncc(NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)OCc2ccccc2)c1N -US20150005279A1,1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.N#Cc1ccc(F)c2cc[nH]c12>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2ccc(C#N)c3[nH]ccc23)C1 -US20040192685A1,1,O=Cc1ccc(-n2ccnc2)cc1.Oc1ccc2c(c1)CCNC2c1ccc(OCCN2CCCC2)cc1>>Oc1ccc2c(c1)CCN(Cc1ccc(-n3ccnc3)cc1)C2c1ccc(OCCN2CCCC2)cc1 -US20070254867A1,1,CC(C)(O)c1ccc2c(c1)NC(=O)c1ccc(Cl)cc1N2.Nc1ccncc1>>CC(C)(O)c1ccc2c(c1)NC(=O)c1ccc(Nc3ccncc3)cc1N2 -US05538987,4,CC(N)=S.CCOC(=O)C(Br)C(=O)c1ccc(C)cc1>>CCOC(=O)c1sc(C)nc1-c1ccc(C)cc1 -US04939161,1,COC(=O)C1CN(Cc2ccccc2)CC(C)C1=O.Nc1ccccc1>>COC(=O)C1CN(Cc2ccccc2)CC(C)C1Nc1ccccc1 -US20110053910A1,1,CN1CC(C)(C)Cc2nc(Cl)sc2C1=O.Cn1ccc(NC(=O)c2cc(O)cc(O[C@H]3CCOC3)c2)n1>>CN1CC(C)(C)Cc2nc(Oc3cc(O[C@H]4CCOC4)cc(C(=O)Nc4ccn(C)n4)c3)sc2C1=O -US20040192708A1,2,CC(C)S(=O)(=O)Cl.CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(N)cc3)nc21>>CCCCn1c(=O)n(Cc2ccccc2F)c(=O)c2[nH]c(Cc3ccc(NS(=O)(=O)C(C)C)cc3)nc21 -US20120202785A1,7,Cc1c(F)ccc([N+](=O)[O-])c1Nc1ccccn1>>Cc1c(F)ccc(N)c1Nc1ccccn1 -US20080039450A1,2,CN(C)CCCN.COc1cc(C(=O)O)ccc1Nc1cncc(-c2ccc(O)cc2)n1>>COc1cc(C(=O)NCCCN(C)C)ccc1Nc1cncc(-c2ccc(O)cc2)n1 -US20100311729A1,2,NCCCOc1ccc(-c2ccc3ncc(-c4cnc(N)c(C(F)(F)F)c4)n3n2)cc1.O=C(O)C1CC1>>Nc1ncc(-c2cnc3ccc(-c4ccc(OCCCNC(=O)C5CC5)cc4)nn23)cc1C(F)(F)F -US20070281937A1,6,CCOC(=O)c1cn(-c2ccc(Cl)cc2)c(CN(C)c2ccc(F)cc2)n1>>CN(Cc1nc(C(=O)O)cn1-c1ccc(Cl)cc1)c1ccc(F)cc1 -US20070254869A1,6,CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)(C)C)c2ccc(C(F)(F)F)cc21>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCNc2ccc(C(F)(F)F)cc21 -US20100272680A1,2,COC(=O)c1nc2c(C(F)(F)F)cc(OC(C)C)cn2c1Cl.O=C1OCCN1C1CCNCC1>>CC(C)Oc1cc(C(F)(F)F)c2nc(C(=O)N3CCC(N4CCOC4=O)CC3)c(Cl)n2c1 -US20090099183A1,1,CCOc1ccc(Br)cc1-c1cc(Cl)nc(N)n1.NC(=O)c1ccc(N)cc1>>CCOc1ccc(Br)cc1-c1cc(Nc2ccc(C(N)=O)cc2)nc(N)n1 -US20110130415A1,1,CI.O=c1[nH]nnn1-c1cc([N+](=O)[O-])cc(Br)c1F>>Cn1nnn(-c2cc([N+](=O)[O-])cc(Br)c2F)c1=O -US20090239810A1,2,Cc1ccc(C#N)cc1OC1CNC1.O=C(O)CNC(=O)c1cn(-c2ccccc2)cn1>>Cc1ccc(C#N)cc1OC1CN(C(=O)CNC(=O)c2cn(-c3ccccc3)cn2)C1 -US05409943,2,Fc1ccc(N=C=S)cc1.Nc1ncccc1OCc1c(F)cccc1Cl>>Fc1ccc(NC(=S)Nc2ncccc2OCc2c(F)cccc2Cl)cc1 -US08097622B2,2,CC[C@@H]1CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)CCN1.C[C@H](O)C(=O)O>>CC[C@@H]1CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)CCN1C(=O)[C@H](C)O -US20110130453A1,1,CCOC(=O)Cc1ccc(OC)c(Oc2ccc(C(F)(F)F)cc2C=O)c1.NCc1ccccc1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(C(F)(F)F)cc2CNCc2ccccc2)c1 -US20090163488A1,2,Cn1nnc(C(=O)O)n1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3c2)c1>>Cn1nnc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c2)n1 -US08541448B2,7,CN1Cc2c(Cl)cc(Cl)cc2C(c2ccc(NC(=O)NCCC(=O)C3C(=O)OC(C)(C)OC3=O)cc2)C1>>CN1Cc2c(Cl)cc(Cl)cc2C(c2ccc(NC(=O)NCCCC3C(=O)OC(C)(C)OC3=O)cc2)C1 -US20140336224A1,7,CCC(C#N)(c1ccc(Cl)cc1)c1n[nH]c2c([N+](=O)[O-])cccc12>>CCC(C#N)(c1ccc(Cl)cc1)c1n[nH]c2c(N)cccc12 -US20050182040A1,6,CC(C)(C)OC(=O)NC1CCC(Nc2ccc(C(N)=O)cc2)CC1>>NC(=O)c1ccc(NC2CCC(N)CC2)cc1 -US20130131018A1,1,CCCCCBr.COc1cc(C=O)cc(OC)c1O>>CCCCCOc1c(OC)cc(C=O)cc1OC -US08034812B2,2,CCn1ccc(C(=O)O)n1.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F>>CCn1ccc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2F)n1 -US05849911,2,CCOC(=O)N[C@H](C(=O)O)C(C)C.COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(N)Cc1ccc(-c2cncs2)cc1)C(C)(C)C>>CCOC(=O)N[C@H](C(=O)NN(Cc1ccc(-c2cncs2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)C -US08513273B2,3,CN1C(=O)N(c2ccc(C#C[Si](C)(C)C)cn2)C2CCCC21.Fc1cccc(I)c1>>CN1C(=O)N(c2ccc(C#Cc3cccc(F)c3)cn2)C2CCCC21 -US06515011B2,7,N#Cc1cc(Cl)ccc1CN1CC(F)(F)C1>>NCc1cc(Cl)ccc1CN1CC(F)(F)C1 -US20130102009A1,6,CCCNc1cc(-c2nc3c(NC(=O)c4cccc(C5CCN(C(=O)OC(C)(C)C)C5)c4)cccc3[nH]2)ccn1>>CCCNc1cc(-c2nc3c(NC(=O)c4cccc(C5CCNC5)c4)cccc3[nH]2)ccn1 -US20140088078A1,6,COC(=O)c1c(NS(=O)(=O)c2ccccc2F)ccc2c1OCC1CC21>>O=C(O)c1c(NS(=O)(=O)c2ccccc2F)ccc2c1OCC1CC21 -US06911467B2,2,C[C@@H](OC(C)(C)C)[C@H](N)C(=O)N1CCC[C@H]1C#N.O=C(Cl)OCc1ccccc1>>C[C@@H](OC(C)(C)C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C#N -US20120238750A1,1,CCOC(=O)CCc1ccc(N)c(OC)c1.O=[N+]([O-])c1ccc(Cl)nc1>>CCOC(=O)CCc1ccc(Nc2ccc([N+](=O)[O-])cn2)c(OC)c1 -US20150148313A1,1,CN.O=Cc1cc([N+](=O)[O-])cc(F)c1O>>CNCc1cc([N+](=O)[O-])cc(F)c1O -US20120028973A1,1,CC(C)[Si](OC[C@H](O)COCc1ccccc1)(C(C)C)C(C)C.Oc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1>>CC(C)[Si](OC[C@H](COCc1ccccc1)Oc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1)(C(C)C)C(C)C -US20150232445A1,1,C[C@H]1CCc2c(ccc(-c3cnn(C4CCNCC4)c3)c2Oc2cccc(F)n2)N1C(=O)C1CC1.C[O-]>>COc1cccc(Oc2c(-c3cnn(C4CCNCC4)c3)ccc3c2CC[C@H](C)N3C(=O)C2CC2)n1 -US20050090504A1,6,CC(C)C(NC(=O)OC(C)(C)C)C(=O)N1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>CC(C)C(N)C(=O)N1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 -US07902400B2,2,C#CCOc1c(OC)cc(C(=O)Cl)cc1OC.C[C@H](N)C1CCCCC1>>C#CCOc1c(OC)cc(C(=O)N[C@@H](C)C2CCCCC2)cc1OC -US20120077801A1,6,CN(C)Cc1ccc(-c2cccc(-n3c(=O)n([C@@H]4CC[C@H](NC(=O)OC(C)(C)C)CC4)c(=O)c4cc(F)cnc43)c2)cc1>>CN(C)Cc1ccc(-c2cccc(-n3c(=O)n([C@@H]4CC[C@H](N)CC4)c(=O)c4cc(F)cnc43)c2)cc1 -US09156840B2,1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1.O=c1[nH]c2ccc(Cl)cc2n1CCCCl>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCn4c(=O)[nH]c5ccc(Cl)cc54)CC3)C2=O)c1 -US07176212B2,1,CN(C)CC(O)CN(C)c1ccc(N)cc1.Cc1ccc(F)c(Nc2ccnc(Cl)n2)c1>>Cc1ccc(F)c(Nc2ccnc(Nc3ccc(N(C)CC(O)CN(C)C)cc3)n2)c1 -US20110294779A1,2,CCOC(=O)c1cnn(C)c1C(=O)Cl.Nc1cc2nc(-c3ccccc3)cn2cc1Br>>CCOC(=O)c1cnn(C)c1C(=O)Nc1cc2nc(-c3ccccc3)cn2cc1Br -US09102654B2,6,COC(=O)c1cc(Cl)nn1-c1cccnc1>>O=C(O)c1cc(Cl)nn1-c1cccnc1 -US20070135485A1,4,CC(C)(C)[SiH2]OC(C)(C)c1ccc2cc(C(=O)NNC(=O)CSCCOc3ccccc3)ccc2c1>>CC(C)(C)[SiH2]OC(C)(C)c1ccc2cc(-c3nnc(CSCCOc4ccccc4)o3)ccc2c1 -US20080015237A1,3,CC1(C)COC(c2ccc(F)cc2)=N1.CN(C)C=O>>CC1(C)COC(c2ccc(F)cc2C=O)=N1 -US20130190289A1,6,COC(=O)c1sc(C#CC(C)(C)OC)cc1N(CC(=O)N1CCOCC1)C(=O)[C@@H]1CC[C@@H](C)CC1>>COC(C)(C)C#Cc1cc(N(CC(=O)N2CCOCC2)C(=O)[C@@H]2CC[C@@H](C)CC2)c(C(=O)O)s1 -US20090082434A1,9,Cc1cccc(C)c1-c1cccc2c1OC(CN=[N+]=[N-])C2>>Cc1cccc(C)c1-c1cccc2c1OC(CN)C2 -US20140018380A1,2,CCc1cnc(N2CCC(O)CC2)nc1.CS(=O)(=O)Cl>>CCc1cnc(N2CCC(OS(C)(=O)=O)CC2)nc1 -US20090012077A1,1,COc1cc(F)ccc1Cl.NN=C(c1ccccc1)c1ccccc1>>COc1cc(F)ccc1NN=C(c1ccccc1)c1ccccc1 -US07507760B2,9,CCOC(=O)[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)OC(C)(C)C>>CCOC(=O)[C@@H]1C[C@H](N)CN1C(=O)OC(C)(C)C -US20130240784A1,3,CCCC1CC=C(c2ccc(Br)cc2F)CC1.CN(C)C=O>>CCCC1CC=C(c2ccc(Br)c(C=O)c2F)CC1 -US20150073146A1,1,CC1(C)O[C@H]2[C@H](N)C[C@H](OCCO)[C@H]2O1.CCCSc1nc(Cl)c(N)c(Cl)n1>>CCCSc1nc(Cl)c(N)c(N[C@@H]2C[C@H](OCCO)[C@H]3OC(C)(C)O[C@@H]23)n1 -US20130116243A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nn(CC(F)(F)F)c3=O)CO4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nn(CC(F)(F)F)c3=O)CO4)cc2)CCC1 -US04576911,2,C=CC(=O)Cl.NC1=NN(c2cc(Cl)cc(Cl)c2)C(=O)C1>>C=CC(=O)NC1=NN(c2cc(Cl)cc(Cl)c2)C(=O)C1 -US04501687,2,C=CCC1CCC(C)(O)C1(C)C.CC(=O)Cl>>C=CC[C@@H]1CC[C@@](C)(OC(C)=O)C1(C)C -US20090181950A1,6,COC(=O)CCc1cnc2c(N3CCN(C(=O)OC(C)(C)C)CC3)cccc2c1>>COC(=O)CCc1cnc2c(N3CCNCC3)cccc2c1 -US08097634B2,2,CC(C)(C)CC(=O)Cl.O=C1CC2(CCN1)CCN(c1ccc(OCC(F)(F)F)cc1)C2=O>>CC(C)(C)CC(=O)N1CCC2(CCN(c3ccc(OCC(F)(F)F)cc3)C2=O)CC1=O -US06403584B1,3,COc1cccc(OC)c1B(O)O.O=C(OCc1ccccc1)c1ccc(Cl)cc1OCc1ccccc1>>COc1cccc(OC)c1-c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1 -US07452892B2,1,CCI.CCNC1(C(N)=O)CN(c2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c3n[nH]c(=O)n23)C1>>CCNC1(C(N)=O)CN(c2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c3nn(CC)c(=O)n23)C1 -US05691384,2,CC(=O)OC(C)=O.Nc1ccc(C(=O)c2ccccc2)cc1>>CC(=O)Nc1ccc(C(=O)c2ccccc2)cc1 -US20060247251A1,4,C#CCc1ccc(CO)cc1.N#Cc1ncc(Br)c(NCCC2CCCCC2)n1>>N#Cc1ncc2cc(Cc3ccc(CO)cc3)n(CCC3CCCCC3)c2n1 -US20120295903A1,1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CC=O)c2cc1C.O=C(O)[C@@H]1CCCN1>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN3CCC[C@H]3C(=O)O)c2cc1C -US06214852B1,1,CC(C)(C)c1cnc(CSc2cnc(NC(=O)Cc3ccc(CBr)cc3)s2)o1.NC[C@@H](O)CO>>CC(C)(C)c1cnc(CSc2cnc(NC(=O)Cc3ccc(CNC[C@@H](O)CO)cc3)s2)o1 -US20140315917A1,1,CNC(=O)c1cc(Cl)ccn1.Nc1ccc(O)cn1>>CNC(=O)c1cc(Oc2ccc(N)nc2)ccn1 -US05411963,1,CC(C)(C)c1ccc(CCO)cc1.Clc1ncnc2ccccc12>>CC(C)(C)c1ccc(CCOc2ncnc3ccccc23)cc1 -US07714008B2,3,CC1(C)CCC=C1B1OC(C)(C)C(C)(C)O1.CCOC(=O)C[C@@H](c1ccc(OCc2ccc(Cl)c(OC(F)(F)F)c2)cc1)c1ccon1>>CCOC(=O)C[C@@H](c1ccc(OCc2ccc(C3=CCCC3(C)C)c(OC(F)(F)F)c2)cc1)c1ccon1 -US20110009454A1,7,N#Cc1cccc(Oc2ccccc2Cl)c1>>NCc1cccc(Oc2ccccc2Cl)c1 -US20110105436A1,4,NC(=S)Nc1ccc(O)cc1.O=C(CBr)c1ccncc1>>Oc1ccc(Nc2nc(-c3ccncc3)cs2)cc1 -US20040053956A1,2,O=C(Cl)OCC(Cl)(Cl)Cl.c1ccc2c(c1)CCNC2>>O=C(OCC(Cl)(Cl)Cl)N1CCc2ccccc2C1 -US05684004,1,ClCCCCCBr.Oc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1>>ClCCCCCOc1ccc(C(=C(Cl)c2ccccc2)c2ccccc2)cc1 -US20120094992A1,1,CCNC(=O)c1ccc(N2CCNCC2)c(Cl)c1.CCOc1cc(C=O)cc2c1OC(C)C(=O)N2>>CCNC(=O)c1ccc(N2CCN(Cc3cc4c(c(OCC)c3)OC(C)C(=O)N4)CC2)c(Cl)c1 -US06498165B1,3,COc1cc(B(O)O)cc(OC)c1OC.C[C@H](Nc1nccc(-n2cnc3cc(I)ccc32)n1)c1ccccc1>>COc1cc(-c2ccc3c(c2)ncn3-c2ccnc(N[C@@H](C)c3ccccc3)n2)cc(OC)c1OC -US06022492,1,CCCCCCCCBr.CCCCCCCCOc1ccc(-c2cnc(-c3ccc(O)c(F)c3F)nc2)cn1>>CCCCCCCCOc1ccc(-c2cnc(-c3ccc(OCCCCCCCC)c(F)c3F)nc2)cn1 -US08901118B2,9,CCOc1ncnc2[nH]cc(Cc3ccc(Nc4ccc(Br)nc4)nc3F)c12>>CCOc1ncnc2[nH]cc(Cc3ccc(Nc4cccnc4)nc3F)c12 -US20020193385A1,7,O=[N+]([O-])c1ccc(F)c(-c2cnccn2)c1>>Nc1ccc(F)c(-c2cnccn2)c1 -US07557127B2,1,CCOC(=O)/C=C/c1cnc(Cl)cn1.N[C@@H]1CCN(Cc2ccccc2)C1>>CCOC(=O)/C=C/c1cnc(N[C@@H]2CCN(Cc3ccccc3)C2)cn1 -US20110118238A1,1,CN1CCC(O)C1.COc1cc(F)ccc1[N+](=O)[O-]>>COc1cc(OC2CCN(C)C2)ccc1[N+](=O)[O-] -US20100063013A1,7,CCOC(=O)[C@H](CC(C)(C)F)NC(=O)OCc1ccccc1>>CC(C)(F)C[C@@H](CO)NC(=O)OCc1ccccc1 -US20090170791A1,6,CCOC(=O)c1cn2c3c(cc(I)cc3c1=O)OCC2>>O=C(O)c1cn2c3c(cc(I)cc3c1=O)OCC2 -US07897601B2,3,C#CC(C)O.Clc1ccc(I)cc1>>CC(O)C#Cc1ccc(Cl)cc1 -US07132425B2,3,CCCC[Sn](CCCC)(CCCC)C1=CCCCO1.Nc1cnc(Br)cn1>>Nc1cnc(C2=CCCCO2)cn1 -US20040138223A1,6,CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cc1>>CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCCc3c(O)cccc32)cc1 -US20090227560A1,4,CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn(C3CCCCC3(O)CCC#N)c2-c2ccccc2)[C@H](Cc2ccccc2)C1.C[Si](C)(C)N=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn(C3CCCCC3(O)CCc3nnn[nH]3)c2-c2ccccc2)[C@H](Cc2ccccc2)C1 -US08859774B2,6,CC(C)(C)OC(=O)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(C(=O)c2ccccn2)C1>>O=C(c1ccccn1)[C@@]12CNCCC1=Cc1c(cnn1-c1ccc(F)cc1)C2 -US06537948B1,7,CCOC(=O)COc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1[N+](=O)[O-]>>CCOC(=O)COc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1N -US20080009523A1,2,CCOC(=O)c1cc(C#N)c(N2CCC(S(N)(=O)=O)CC2)nc1C.COC(C(=O)O)c1ccccc1>>CCOC(=O)c1cc(C#N)c(N2CCC(S(=O)(=O)NC(=O)C(OC)c3ccccc3)CC2)nc1C -US20080045521A1,6,CNc1cccc(CCCOc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)OC)cc2)n1>>CNc1cccc(CCCOc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)n1 -US07635715B2,2,CCO.O=C(O)Cc1ccc(C(F)(F)F)cc1>>CCOC(=O)Cc1ccc(C(F)(F)F)cc1 -US05693647,3,COC(=O)c1cc([N+](=O)[O-])ccc1Br.COc1ccc(C)cc1B(O)O>>COC(=O)c1cc([N+](=O)[O-])ccc1-c1cc(C)ccc1OC -US06815451B2,1,CC(C)(C)OC(=O)NCCBr.COc1cc2c(cc1OC)C(Cc1ccc(F)cc1)NCC2>>COc1cc2c(cc1OC)C(Cc1ccc(F)cc1)N(CCNC(=O)OC(C)(C)C)CC2 -US20150203472A1,3,Fc1ccc(-n2cnc3ccc(Br)cc32)c(F)c1.OB(O)c1ccnn1-c1ccc(F)cc1>>Fc1ccc(-n2nccc2-c2ccc3ncn(-c4ccc(F)cc4F)c3c2)cc1 -US09067937B2,1,CC(=O)c1cnc2ccc(Cl)nc2c1Cl.CN1CCN(C[C@@H]2CC[C@@H](N)CC2)CC1>>CC(=O)c1cnc2ccc(Cl)nc2c1N[C@@H]1CC[C@@H](CN2CCN(C)CC2)CC1 -US20110130453A1,2,CCNCc1cc(C(F)(F)F)ccc1Oc1cccc(CC(=O)OC)c1.O=S(=O)(Cl)c1ccc(Br)cc1>>CCN(Cc1cc(C(F)(F)F)ccc1Oc1cccc(CC(=O)OC)c1)S(=O)(=O)c1ccc(Br)cc1 -US20080200475A1,1,CCc1cc2c(Cl)nc(Cl)nc2s1.O=C(Cc1ccccc1)N1CCNCC1>>CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(Cl)nc2s1 -US07943654B2,6,CCOC(=O)n1nc(NC(=O)c2ccccc2NC(=O)c2ccc[nH]2)c2cc(C(=O)OC(C)(C)C)sc21>>CCOC(=O)n1nc(NC(=O)c2ccccc2NC(=O)c2ccc[nH]2)c2cc(C(=O)O)sc21 -US05576324,9,CC1(C)CC(=O)Nc2c(Br)cc3c(c21)OC(CN=[N+]=[N-])C3>>CC1(C)CC(=O)Nc2c(Br)cc3c(c21)OC(CN)C3 -US04843087,1,Cc1cc(CCCCCBr)on1.Oc1c(Cl)cc(C2=NCCO2)cc1Cl>>Cc1cc(CCCCCOc2c(Cl)cc(C3=NCCO3)cc2Cl)on1 -US20100099718A1,1,COCc1ccc(-c2nn[nH]n2)c(N)n1.ClCc1ccc(OCc2ccccc2)cc1>>COCc1ccc(-c2nnn(Cc3ccc(OCc4ccccc4)cc3)n2)c(N)n1 -US20070010670A1,2,FC(F)(F)c1ccc2c(c1)NCCO2.O=C(Cl)c1cc(Cl)c(O)c(Cl)c1>>O=C(c1cc(Cl)c(O)c(Cl)c1)N1CCOc2ccc(C(F)(F)F)cc21 -US20120178755A1,2,CCCCOC(=O)c1nc(C#N)c2ccc(OC3CCCCC3)cc2c1O.NCC(=O)O>>N#Cc1nc(C(=O)NCC(=O)O)c(O)c2cc(OC3CCCCC3)ccc12 -US20150284404A1,9,[N-]=[N+]=NC[C@H]1COc2cccnc2O1>>NC[C@H]1COc2cccnc2O1 -US04411900,1,CC(=O)Nc1nc(CCl)cs1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>CC(=O)Nc1nc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cs1 -US20150274708A1,6,Cn1cc(NC(=O)c2cccc(-c3ccnc(N(CC4CC4)C(=O)OC(C)(C)C)c3)n2)c(C(N)=O)n1>>Cn1cc(NC(=O)c2cccc(-c3ccnc(NCC4CC4)c3)n2)c(C(N)=O)n1 -US20030225064A1,7,CS(=O)(=O)c1ccc(-n2ncc([N+](=O)[O-])c2-c2ccc(Br)cc2)cc1F>>CS(=O)(=O)c1ccc(-n2ncc(N)c2-c2ccc(Br)cc2)cc1F -US08410107B2,2,Nc1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1.O=C(O)c1ccccc1>>O=C(Nc1cnc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)c1)c1ccccc1 -US20090012300A1,1,Brc1ccccc1.NCc1ccccc1>>c1ccc(CNc2ccccc2)cc1 -US06326369B1,1,COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCI)C2.O=C1NC(=O)c2ccccc21>>COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCN1C(=O)c3ccccc3C1=O)C2 -US20060094718A1,2,O=C(Cl)N1CCOCC1.O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(C=Cc2ccccc2)ccc1O>>O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(C=Cc2ccccc2)ccc1OC(=O)N1CCOCC1 -US20080009530A1,7,CCOC(=O)/C=C/c1ccc(OCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CCOC(=O)CCc1ccc(OCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl -US20060142570A1,1,CN1CCN(c2ccnc(Cl)n2)CC1.Nc1ccc2sc(NC(=O)c3ccccc3)nc2c1>>CN1CCN(c2ccnc(Nc3ccc4sc(NC(=O)c5ccccc5)nc4c3)n2)CC1 -US20150252069A1,6,COc1cc(C[C@@]2(CCO[Si](C)(C)C(C)(C)C)OC(C)(C)O[C@H]2C)c(OC)c2c(OC)c3ccccc3c(OC)c12>>COc1cc(C[C@@]2(CCO)OC(C)(C)O[C@H]2C)c(OC)c2c(OC)c3ccccc3c(OC)c12 -US20080103123A1,1,C=O.CC(C)(C)OC(=O)N1CCC(NCc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)CC1>>CN(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(C(=O)OC(C)(C)C)CC1 -US20110059940A1,6,CC(C)(C)OC(=O)c1ccc(CN(C(C(N)=O)c2cc(F)cc(F)c2)S(=O)(=O)c2ccc(Cl)cc2)cc1>>NC(=O)C(c1cc(F)cc(F)c1)N(Cc1ccc(C(=O)O)cc1)S(=O)(=O)c1ccc(Cl)cc1 -US06479485B2,9,CCOC(=O)c1ccc(Oc2c(F)c(Oc3cccc(N)c3)nc(Oc3cc(C#N)ccc3OCc3ccccc3)c2F)c(OC)c1.N#CN>>CCOC(=O)c1ccc(Oc2c(F)c(Oc3cccc(NC(=N)N)c3)nc(Oc3cc(C#N)ccc3OCc3ccccc3)c2F)c(OC)c1 -US05245028,2,NCCC1(O)CCc2ccccc2C12CCCC2.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(NCCC1(O)CCc2ccccc2C12CCCC2)OCC(Cl)(Cl)Cl -US20100317656A1,6,CCOC(=O)c1cn2cc(-c3ccco3)ccc2n1>>O=C(O)c1cn2cc(-c3ccco3)ccc2n1 -US20080293940A1,2,CC(C)(C)OC(=O)N1CCN(Cc2ccc(C(=O)O)cc2C(F)(F)F)CC1.Cc1ccc(N)cc1Nc1cc(-c2cccnc2)ccn1>>Cc1ccc(NC(=O)c2ccc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(C(F)(F)F)c2)cc1Nc1cc(-c2cccnc2)ccn1 -US20080242681A1,1,CC(C)(C)OC(=O)Nc1ccc(N)cc1.Clc1cc(Cl)ncn1>>CC(C)(C)OC(=O)Nc1ccc(Nc2cc(Cl)ncn2)cc1 -US05665718,6,O=C1c2ccccc2C(=O)N1Cc1nnc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2sccc2-3)o1>>NCc1nnc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2sccc2-3)o1 -US20140364414A1,3,Brc1cnc(N2CCOCC2)c2nc(CCc3ccc4ccccc4n3)cn12.CC1(C)OB(c2ccc(C#N)nc2)OC1(C)C>>N#Cc1ccc(-c2cnc(N3CCOCC3)c3nc(CCc4ccc5ccccc5n4)cn23)cn1 -US20150284344A1,4,CC(=O)c1ccc(Oc2ccc(Cl)cc2)cc1C.C[S+](C)C>>Cc1cc(Oc2ccc(Cl)cc2)ccc1C1(C)CO1 -US08263610B2,6,CC(C)(C)OC(=O)N1CCN(C(C(=O)N2CCc3c(cnc4[nH]nc(Br)c34)C2)c2ccccc2)CC1>>O=C(C(c1ccccc1)N1CC[NH2+]CC1)N1CCc2c(cnc3[nH]nc(Br)c23)C1 -US07674825B2,7,COC(=O)c1ccc(C=C2CCOC2=O)cc1>>COC(=O)c1ccc(CC2CCOC2=O)cc1 -US20120214803A1,2,COC(=O)c1ccnc2c(N)cccc12.O=S(=O)(Cl)c1ccccc1>>COC(=O)c1ccnc2c(NS(=O)(=O)c3ccccc3)cccc12 -US20060009456A1,7,COc1ccc([C@H]2CC(=O)C[C@H]3CN(Cc4ccccc4)CCN32)c(C)c1C>>COc1ccc([C@H]2CCC[C@H]3CN(Cc4ccccc4)CCN32)c(C)c1C -US20090099227A1,1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.NCc1noc(-c2cc3cnccc3o2)n1>>CC(C)(C)OC(=O)N1CCC(CNCc2noc(-c3cc4cnccc4o3)n2)CC1 -US06329546B1,7,CCOC(=O)C(C)=Cc1cc(OC)c(OC)cc1[N+](=O)[O-]>>CCOC(=O)C(C)=Cc1cc(OC)c(OC)cc1N -US20120059002A1,1,Cc1cc(C=O)cc(C)c1O.Cc1cc(NCCBr)no1>>Cc1cc(NCCOc2c(C)cc(C=O)cc2C)no1 -US20090258861A1,2,CC(C)N1CCC(Oc2ccc3c(n2)CCN(c2ccc(C(=O)O)nc2)C3)CC1.CN>>CNC(=O)c1ccc(N2CCc3nc(OC4CCN(C(C)C)CC4)ccc3C2)cn1 -US20140051654A1,2,Nc1cc(Cl)c(C(F)(F)F)cc1N.O=C(O)CCC1CC(=O)C1>>Nc1cc(Cl)c(C(F)(F)F)cc1NC(=O)CCC1CC(=O)C1 -US07989477B2,7,O=[N+]([O-])c1ccc(O)c(F)c1>>Nc1ccc(O)c(F)c1 -US04588749,1,CC(=O)Cc1ccc(C)cc1.NCC(O)c1ccccc1>>Cc1ccc(CC(C)NCC(O)c2ccccc2)cc1 -US04014915,2,CC(C)(C)O.O=C(Cl)On1nnc2ccc(Cl)cc21>>CC(C)(C)OC(=O)On1nnc2ccc(Cl)cc21 -US20150225412A1,6,CC(C)(C)OC(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccc(C(F)F)s2)nc2cc(CO)ccc21>>O=C(Nc1nc2cc(CO)ccc2n1C[C@H]1CCCN1)c1ccc(C(F)F)s1 -US20050234244A1,6,CCOC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2cc(Cl)c(OC)cc12>>COc1cc2c(CC(=O)O)c(C)n(C(=O)c3ccc(Cl)cc3)c2cc1Cl -US04378991,2,Cc1cc(C)nc(N)n1.O=C=NS(=O)(=O)c1ccccc1-c1ccccc1>>Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2-c2ccccc2)n1 -US20150018343A1,6,CCOC(=O)c1ccc(F)cc1OCC>>CCOc1cc(F)ccc1C(=O)O -US06040338,1,CN(NS(C)(=O)=O)S(C)(=O)=O.O=C(Cl)OCCBr>>CN(N(C(=O)OCCBr)S(C)(=O)=O)S(C)(=O)=O -US20090270363A1,7,COC(=O)c1cc([N+](=O)[O-])ccc1Br>>COC(=O)c1cc(N)ccc1Br -US07642256B2,2,Brc1ccc(C2CCCN2)cc1.CC(=O)Cl>>CC(=O)N1CCCC1c1ccc(Br)cc1 -US06096746,1,Fc1ccc(CCl)cc1.OCCN1CCNCC1>>OCCN1CCN(Cc2ccc(F)cc2)CC1 -US03968211,2,NC1CCCCC1.O=C(Cl)CC1CCCCC1>>O=C(CC1CCCCC1)NC1CCCCC1 -US05401710,1,CC(=O)Cl.COC(=O)C(C(C)C)S(=O)(=O)Nc1nc(OC)cc(OC)n1>>COC(=O)C(C(C)C)S(=O)(=O)N(C(C)=O)c1nc(OC)cc(OC)n1 -US06958343B2,1,C[C@H](CO)Nc1nc(S)nc2nc(N)sc12.Cc1noc(C)c1CCl>>Cc1noc(C)c1CSc1nc(N[C@H](C)CO)c2sc(N)nc2n1 -US09006255B2,1,Clc1ncnc2ccc(I)cc12.c1ccc2c(c1)CCCN2>>Ic1ccc2ncnc(N3CCCc4ccccc43)c2c1 -US06376409B1,3,CC1=Cc2c(Cl)cccc2C1.Cc1cc(C)cc([Mg+])c1>>CC1=Cc2c(cccc2-c2cc(C)cc(C)c2)C1 -US20140275179A1,6,CCOC(=O)CCc1cc(F)c(OCc2c(-c3ccc(C)nc3)csc2C(F)(F)F)c(F)c1>>Cc1ccc(-c2csc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cn1 -US05468898,7,CCOC(=O)C=Cc1cn(CC(=O)N(C)CCc2ccccc2)c2ccc(OCc3ccccc3)cc12>>CCOC(=O)CCc1cn(CC(=O)N(C)CCc2ccccc2)c2ccc(OCc3ccccc3)cc12 -US20050256180A1,1,CN.NC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CCc1ccc(NC(=O)c3nc(Cl)ccc3Cl)cc1-2>>CNc1ccc(Cl)c(C(=O)Nc2ccc3c(c2)-c2c(c(C(N)=O)nn2-c2ccc4c(c2)OCO4)CC3)n1 -US20090264482A1,1,CC(=O)Nc1ccc(OCCBr)cc1.Cc1cc2c(Cl)c(C#N)ccc2[nH]1>>CC(=O)Nc1ccc(OCCn2c(C)cc3c(Cl)c(C#N)ccc32)cc1 -US20080009534A1,6,COC(=O)CN(C(=O)Oc1cccc(OC)c1)[C@@H](C)c1ccc(O[Si](C)(C)C(C)(C)C)cc1>>COC(=O)CN(C(=O)Oc1cccc(OC)c1)[C@@H](C)c1ccc(O)cc1 -US20130225589A1,6,CC(C)(C)OC(=O)N1CCc2cc(Nc3ncc4c(=O)n(-c5c(Cl)cccc5Cl)cc(-c5ncc[nH]5)c4n3)ccc2C1>>O=c1c2cnc(Nc3ccc4c(c3)CCNC4)nc2c(-c2ncc[nH]2)cn1-c1c(Cl)cccc1Cl -US07790720B2,2,C1COCCN1.CCOC(=O)c1sc(-c2ccc(Cl)nc2)nc1C>>Cc1nc(-c2ccc(Cl)nc2)sc1C(=O)N1CCOCC1 -US06887896B1,3,CCOC(=O)C=C(C)CP(=O)(OCC)OCC.CCOc1c(/C(CC)=C(/F)C=O)cc2c(c1Br)C(C)(C)CC=C2C(C)CC>>CCOC(=O)/C=C(C)/C=C/C(F)=C(/CC)c1cc2c(c(Br)c1OCC)C(C)(C)CC=C2C(C)CC -US20090048285A1,6,CCOC(=O)c1cc2cc(Oc3cccc(C(F)(F)F)c3)ncc2n1-c1ccc(OC(C)C)cc1>>CC(C)Oc1ccc(-n2c(C(=O)O)cc3cc(Oc4cccc(C(F)(F)F)c4)ncc32)cc1 -US08288375B2,2,CC(=O)OC(C)=O.Fc1ccc(-c2nn3c(c2-c2ccnc(NC4CC4)n2)CCCN3)cc1>>CC(=O)N1CCCc2c(-c3ccnc(NC4CC4)n3)c(-c3ccc(F)cc3)nn21 -US20120309966A1,2,COc1cccc2c1cc(C(=O)Cl)n2C.Cc1nccn2c([C@@H]3CC[C@@H](N4CCN(C)CC4)CC3)nc(-c3ccc(N)c(O)c3)c12>>COc1cccc2c1cc(C(=O)Nc1ccc(-c3nc([C@@H]4CC[C@@H](N5CCN(C)CC5)CC4)n4ccnc(C)c34)cc1O)n2C -US20090156575A1,2,CC1(C)C=Cc2cccc(CN3CCC4(CCNC4)CC3)c2O1.O=C(O)Cc1ccncc1>>CC1(C)C=Cc2cccc(CN3CCC4(CC3)CCN(C(=O)Cc3ccncc3)C4)c2O1 -US20100168101A1,1,N#Cc1ccc(OCC(=O)NN)cc1.O=C1Nc2ccc(I)cc2C1=O>>N#Cc1ccc(OCC(=O)NN=C2C(=O)Nc3ccc(I)cc32)cc1 -US20130030012A1,1,CC(C)N1CCCn2c1cc(Cl)nc2=O.OCc1ccc(Cl)cc1>>CC(C)N1CCCn2c1cc(OCc1ccc(Cl)cc1)nc2=O -US04456776,1,C=CCC.CCC(C)O>>CCC(C)OC(C)CC -US20050054627A1,1,CCC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@H](N)C1=O.FC(F)(F)c1ccc2nccc(Cl)c2c1>>CCC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@@H](Nc2ccnc3ccc(C(F)(F)F)cc23)C1=O -US20050054627A1,1,CCC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@H](N)C1=O.FC(F)(F)c1ccc2nccc(Cl)c2c1>>CCC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@H](Nc2ccnc3ccc(C(F)(F)F)cc23)C1=O -US04808597,7,CC(=O)c1ccc2c(c1)C(C)(C)CCO2>>CC(O)c1ccc2c(c1)C(C)(C)CCO2 -US04863926,7,CCOC(=O)/C(=C/c1ccc(OC)cc1)CC>>CC/C(=C\c1ccc(OC)cc1)CO -US08691991B2,2,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCCC2=O)c1=O.COCCN>>COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCCC2=O)c1=O -US20070254881A1,6,COC(=O)c1cc(-c2ccn(C)n2)n(-c2ccc(OC)nc2)n1>>COc1ccc(-n2nc(C(=O)O)cc2-c2ccn(C)n2)cn1 -US20130040930A1,2,O=C(O)c1ccc(I)cc1F.c1nc(N2CCNCC2)c(C2CC2)cc1C1CC1>>O=C(c1ccc(I)cc1F)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1 -US07476670B2,1,CCOC(=O)c1cccc(N)c1.Clc1nc(-n2cnc3ccccc32)c2nc[nH]c2n1>>CCOC(=O)c1cccc(Nc2nc(-n3cnc4ccccc43)c3nc[nH]c3n2)c1 -US20120220577A1,2,CCOC(=O)CNc1ccccc1.O=C(Cl)CCl>>CCOC(=O)CN(C(=O)CCl)c1ccccc1 -US20140206681A1,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[Si](C)(C)CCOCn1c(-c2cc(C(F)(F)F)ccn2)nc2ccc(Br)cc21>>CC1(C)OB(c2ccc3nc(-c4cc(C(F)(F)F)ccn4)n(COCC[Si](C)(C)C)c3c2)OC1(C)C -US08327467B2,6,CC(C)(C)OC(=O)c1ccc(-c2ccc(CO)cc2)cc1Nc1ccc(F)cc1>>O=C(O)c1ccc(-c2ccc(CO)cc2)cc1Nc1ccc(F)cc1 -US07208493B2,1,NCCc1ccc(O)c(O)c1.Nc1nc(N)c2nc(CBr)cnc2n1>>Nc1nc(N)c2nc(CNCCc3ccc(O)c(O)c3)cnc2n1 -US08877815B2,2,C=C(Cl)CC1(C(=O)O)CCCC1.CN(Cc1ccco1)C(=O)[C@@H](N)Cc1ccc(-c2ccccc2)cc1>>C=C(Cl)CC1(C(=O)N[C@@H](Cc2ccc(-c3ccccc3)cc2)C(=O)N(C)Cc2ccco2)CCCC1 -US20070249710A1,2,CC(C)CO.CC1(C)CCC(C)(C)c2cc(C(=O)COc3ccc(C(=O)O)c(O)c3)ccc21>>CC(C)COC(=O)c1ccc(OCC(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1O -US20130280245A1,9,COc1ccc(-c2ccc(Cl)nc2)cc1.NN>>COc1ccc(-c2ccc(NN)nc2)cc1 -US06107458,4,C#Cc1ccc(OCCCCC)cc1.ON=Cc1ccc(Br)cc1>>CCCCCOc1ccc(-c2cc(-c3ccc(Br)cc3)no2)cc1 -US20070197571A1,7,N#Cc1cccc(CN2CCC3(CC2)C(NC2CCCCC2)=NC(=O)N3c2cccc(F)c2)c1>>NCc1cccc(CN2CCC3(CC2)C(NC2CCCCC2)=NC(=O)N3c2cccc(F)c2)c1 -US20100173955A1,3,CCOC(=O)Cc1ccc(Oc2ccc(C(=O)NCCc3ccc(Cl)cc3)cc2)c(Br)c1.CS(=O)(=O)c1cccc(B(O)O)c1>>CCOC(=O)Cc1ccc(Oc2ccc(C(=O)NCCc3ccc(Cl)cc3)cc2)c(-c2cccc(S(C)(=O)=O)c2)c1 -US20070049632A1,1,CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccc(F)cc3F)c(=O)c12.Clc1ccc(CBr)cc1>>CC1(C)[C@@H]2CC[C@@]1(C)c1c2c(=O)n(-c2ccc(F)cc2F)n1Cc1ccc(Cl)cc1 -US05175301,1,CN.Fc1ccc(CBr)cn1>>CNCc1ccc(F)nc1 -US07855213B2,2,Cc1nn(C)c(Cl)c1S(=O)(=O)Cl.NC1=NC(c2cccc(O)c2)(c2cc(Cl)nc(Cl)c2)c2ccccc21>>Cc1nn(C)c(Cl)c1S(=O)(=O)Oc1cccc(C2(c3cc(Cl)nc(Cl)c3)N=C(N)c3ccccc32)c1 -US20140012003A1,2,CC(C)(C)c1cc2c(cc1N)OC(=O)C2(C)C.O=C(O)c1c[nH]c2ccccc2c1=O>>CC(C)(C)c1cc2c(cc1NC(=O)c1c[nH]c3ccccc3c1=O)OC(=O)C2(C)C -US20120153268A1,3,Brc1cc2ccccc2c2ccccc12.O=Cc1ccccc1B(O)O>>O=Cc1ccccc1-c1cc2ccccc2c2ccccc12 -US20090275590A1,1,COc1cc(F)ccc1-c1cc[nH]c(=O)c1.Cn1c2c(c3ccc(Br)cc31)CN(C(=O)OC(C)(C)C)CC2>>COc1cc(F)ccc1-c1ccn(-c2ccc3c4c(n(C)c3c2)CCN(C(=O)OC(C)(C)C)C4)c(=O)c1 -US20120238540A1,2,COc1cc(Nc2nccc(-c3ccc(OC4CCOCC4)c(C#N)c3)n2)ccc1OCCOCCN.CS(=O)(=O)Cl>>COc1cc(Nc2nccc(-c3ccc(OC4CCOCC4)c(C#N)c3)n2)ccc1OCCOCCNS(C)(=O)=O -US20100137610A1,6,COC(OC)C(CNC(=O)c1cc2c(C)ccc(N(C)S(=O)(=O)c3cccs3)c2[nH]1)SCc1ccccc1>>Cc1ccc(N(C)S(=O)(=O)c2cccs2)c2[nH]c(C(=O)NCC(C=O)SCc3ccccc3)cc12 -US20100004443A1,3,CCCC[Sn](CCCC)(CCCC)c1ccccn1.COc1ccc(Cl)nn1>>COc1ccc(-c2ccccn2)nn1 -US08138187B2,7,COC(=O)Cc1coc2ccccc12>>OCCc1coc2ccccc12 -US06703392B2,1,CCI.COc1cc2c(cc1O)C(Cc1ccc(OC)c(OC)c1)N(CC(=O)NCc1ccccc1)CC2>>CCOc1cc2c(cc1OC)CCN(CC(=O)NCc1ccccc1)C2Cc1ccc(OC)c(OC)c1 -US20070054942A1,3,CCNC(=O)c1ccc(C)c(B2OC(C)(C)C(C)(C)O2)c1.Fc1cc2c(-c3ccc(Cl)nc3)n[nH]c2cc1Br>>CCNC(=O)c1ccc(C)c(-c2cc3[nH]nc(-c4ccc(Cl)nc4)c3cc2F)c1 -US05177075,7,O=c1[nH]ccc2c([N+](=O)[O-])cccc12>>Nc1cccc2c(=O)[nH]ccc12 -US04885299,2,CN[C@@H](CC(C)C)C(=O)O.O=C(Cl)CC1(c2ccccc2)C(=O)Oc2ccc(Cl)cc21>>CC(C)C[C@@H](C(=O)O)N(C)C(=O)CC1(c2ccccc2)C(=O)Oc2ccc(Cl)cc21 -US04551460,7,OCCC#Cc1cncnc1>>OCCCCc1cncnc1 -US08946427B2,2,C1CNC1.Cn1ncc(C(=O)O)c1C(=O)Nc1ccc2nc(-c3cccnc3)nn2c1>>Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccc2nc(-c3cccnc3)nn2c1 -US06858651B2,2,CN[C@@H]1CC[C@@H](O)CC1.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>CN([C@@H]1CC[C@@H](O)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1 -US08288431B2,3,CC(C)(CC=O)CO[Si](C)(C)C(C)(C)C.O=C1Cc2ccc(Cl)cc2N1>>CC(C)(C/C=C1\C(=O)Nc2cc(Cl)ccc21)CO[Si](C)(C)C(C)(C)C -US07354925B2,7,O=C(O)Cc1cc(F)ccc1Br>>OCCc1cc(F)ccc1Br -US20060058259A1,2,CC(C)(CO)NC(=O)OC(C)(C)C.CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(C)(C)NC(=O)OC(C)(C)C -US20150210697A1,7,O=[N+]([O-])c1cc(Br)c(F)c(Br)c1>>Nc1cc(Br)c(F)c(Br)c1 -US06395919B1,9,CCOC(=O)CCCc1ccc(O)c(Br)c1.N#C[Cu]>>CCOC(=O)CCCc1ccc(O)c(C#N)c1 -US06225309B1,2,CCOC(=O)C(N)CNC(=O)C1CCN(c2ccncc2)CC1.O=S(=O)(Cl)c1ccc2ccccc2c1>>CCOC(=O)C(CNC(=O)C1CCN(c2ccncc2)CC1)NS(=O)(=O)c1ccc2ccccc2c1 -US20120220589A1,6,COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCc4cc(C(=O)N5CCOCC5)ccc43)nc2c1>>O=C(O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCc4cc(C(=O)N5CCOCC5)ccc43)nc2c1 -US20080292588A1,1,COC(=O)C1CCCC1N.O=Cc1ccc(F)cc1>>COC(=O)C1CCCC1NCc1ccc(F)cc1 -US20100120798A1,6,CCOC(=O)C1(CN=C(c2ccccc2)c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(CN=C(c2ccccc2)c2ccccc2)CCNCC1 -US03959486,2,C=CCc1cc(OCC(=O)O)ccc1O.CCO>>C=CCc1cc(OCC(=O)OCC)ccc1O -US20090169558A1,7,O=c1[nH]cnc2[nH]c(-c3ccnc(/C=C/c4ccc(CN5CCOCC5)c(F)c4)c3)cc12>>O=c1[nH]cnc2[nH]c(-c3ccnc(CCc4ccc(CN5CCOCC5)c(F)c4)c3)cc12 -US07781430B2,2,CN1C2CCCC1CC(N)C2.O=C(O)c1cccc2oc(-c3ccccc3)nc12>>CN1C2CCCC1CC(NC(=O)c1cccc3oc(-c4ccccc4)nc13)C2 -US06642229B2,1,CCCC[Sn](Cl)(CCCC)CCCC.FC(F)(F)c1ccn2c(Br)cnc2n1>>CCCC[Sn](CCCC)(CCCC)c1cnc2nc(C(F)(F)F)ccn12 -US06080885,2,C=C(C)C(=O)Cl.CCCCCCCC[P+](CCO)(CCCCCCCC)CCCCCCCC>>C=C(C)C(=O)OCC[P+](CCCCCCCC)(CCCCCCCC)CCCCCCCC -US20110105562A1,2,C#CCCCN.CC[C@H](NC(=O)C(F)(F)F)C(=O)O>>C#CCCCNC(=O)[C@H](CC)NC(=O)C(F)(F)F -US08822466B2,1,Cc1oc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1C=O.NC(=O)C1CC1>>Cc1oc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1CNC(=O)C1CC1 -US04093715,2,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1I>>Cc1ccc(S(=O)(=O)OC[C@H]2O[C@@H](n3cc(I)c(N)nc3=O)C[C@@H]2O)cc1 -US20100284970A1,1,Clc1ccc(CBr)cc1.Nc1ccccc1N>>Nc1ccccc1NCc1ccc(Cl)cc1 -US05552420,1,CCc1ncc(CCCO)n1C.Cc1cc(-c2nnn(C)n2)cc(C)c1O>>CCc1ncc(CCCOc2c(C)cc(-c3nnn(C)n3)cc2C)n1C -US07576080B2,6,COC(=O)c1cncc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1>>O=C(O)c1cncc(OCCCOc2ncnc3scc(-c4ccc(F)cc4)c23)c1 -US05703243,7,COc1ccc(COC(=O)N2C[C@H](O)C[C@H]2C(=O)O)cc1>>COc1ccc(COC(=O)N2C[C@H](O)C[C@H]2CO)cc1 -US04977166,1,BrCCC1CCOc2ccccc21.COc1cc(OC)cc(N2CCNCC2)c1>>COc1cc(OC)cc(N2CCN(CCC3CCOc4ccccc43)CC2)c1 -US05972970,3,Cc1cccc(-c2nc(CCOc3ccc(/C=C/C=O)cc3)c(C)o2)c1.O=C1COC(=O)N1>>Cc1cccc(-c2nc(CCOc3ccc(C=CC=C4OC(=O)NC4=O)cc3)c(C)o2)c1 -US20080312208A1,2,CCOC(=O)c1cc(C#N)c(N2CC(C(=O)O)C2)nc1C.NS(=O)(=O)Cc1ccc(Cl)c(Cl)c1>>CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)Cc3ccc(Cl)c(Cl)c3)C2)nc1C -US07678787B2,3,N#CCc1ccccc1Br.O=C(O)c1ccc(B(O)O)cc1>>N#CCc1ccccc1-c1ccc(C(=O)O)cc1 -US20140088084A1,2,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)cc(Br)c2)COC1.O=C(O)c1ncc(Br)cn1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(Br)cc(NC(=O)c3ncc(Br)cn3)c2)COC1 -US20090221555A1,7,CCOC(=O)C1CCN(c2ccc([N+](=O)[O-])c(-n3cccn3)c2)CC1>>CCOC(=O)C1CCN(c2ccc(N)c(-n3cccn3)c2)CC1 -US20150192699A1,2,CC(C)O.O=C(O)c1ccccc1S>>CC(C)OC(=O)c1ccccc1S -US20110306631A1,7,COC(=O)c1cc(Cl)c2c(OC)cc3cccnc3c2n1>>COc1cc2cccnc2c2nc(CO)cc(Cl)c12 -US20060019961A1,6,CC[C@H]1C(=O)N(CC)c2cc(F)ccc2N1S(=O)(=O)c1ccc(OC)cc1>>CC[C@H]1C(=O)N(CC)c2cc(F)ccc2N1S(=O)(=O)c1ccc(O)cc1 -US07396849B2,2,CNOC.O=C(O)c1cccc2nsnc12>>CON(C)C(=O)c1cccc2nsnc12 -US07074801B1,6,CC(C)(C)OC(=O)N1CCN(c2ccc(F)c(C#N)c2)CC1>>N#Cc1cc(N2CCNCC2)ccc1F -US20100249024A1,7,COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cc([N+](=O)[O-])ccc1-c1cc(C(C)C)ccc1OC>>COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cc(N)ccc1-c1cc(C(C)C)ccc1OC -US20080132505A1,1,CC(C)c1cc(Cl)ncc1C(=O)NCC1CCCC1.N#Cc1ccc(N)c(F)c1>>CC(C)c1cc(Nc2ccc(C#N)cc2F)ncc1C(=O)NCC1CCCC1 -US05183906,2,CCCCCCCCCCCC(=O)Cl.CC[Si](CC)(CC)c1occ(CO)c1-c1ccccc1>>CCCCCCCCCCCC(=O)OCc1coc([Si](CC)(CC)CC)c1-c1ccccc1 -US20130203734A1,2,Cc1ccc(S(=O)(=O)Cl)cc1.NC1CCCNC1=O>>Cc1ccc(S(=O)(=O)NC2CCCNC2=O)cc1 -US20090318467A1,2,C1CCN(C2CCNCC2)C1.Cc1cc(-c2cccc(C(F)(F)F)c2)c(Cl)nc1C(=O)O>>Cc1cc(-c2cccc(C(F)(F)F)c2)c(Cl)nc1C(=O)N1CCC(N2CCCC2)CC1 -US20110124633A1,2,CNCc1sc2ccccc2c1C.O=C(O)/C=C/c1cnc2c(c1)CN(CCCN1CCOCC1)CC(=O)N2>>Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CN(CCCN2CCOCC2)CC(=O)N3)sc2ccccc12 -US09102591B2,2,Cc1ncc(C2(CN)CCCO2)cn1.O=C(O)c1cccc(Cl)c1Cl>>Cc1ncc(C2(CNC(=O)c3cccc(Cl)c3Cl)CCCO2)cn1 -US20100016318A1,1,NC(=O)c1cc(Br)ccc1Nc1nc(Cl)ncc1Cl.Nc1cccc(CN2CCCC2)c1>>NC(=O)c1cc(Br)ccc1Nc1nc(Nc2cccc(CN3CCCC3)c2)ncc1Cl -US20040192680A1,2,CC(O)CN.O=C(O)C=Cc1ccccc1Sc1ccc(Cl)cc1>>CC(O)CNC(=O)/C=C/c1ccccc1Sc1ccc(Cl)cc1 -US20040242868A1,2,Cc1ccc(N)cc1-c1ccc(C(=O)NCC2CC2)cc1.O=C(O)c1ccccc1>>Cc1ccc(NC(=O)c2ccccc2)cc1-c1ccc(C(=O)NCC2CC2)cc1 -US04380644,2,CC(C)(C)OC(=O)[C@@H]1CN(Cc2ccccc2)C(=O)N1.C[C@@H](CSC(=O)c1ccccc1)C(=O)Cl>>C[C@H](CSC(=O)c1ccccc1)C(=O)N1C(=O)N(Cc2ccccc2)C[C@H]1C(=O)OC(C)(C)C -US20150189880A1,3,CCS(=O)(=O)c1cc(Cl)cnc1C(=O)N(C)c1ccc(SC(F)(F)F)cc1.OB(O)c1ccccc1>>CCS(=O)(=O)c1cc(-c2ccccc2)cnc1C(=O)N(C)c1ccc(SC(F)(F)F)cc1 -US06759408B2,9,CC1(C)OC(=O)Nc2ccc(-c3coc(C=O)c3)cc21.NO>>CC1(C)OC(=O)Nc2ccc(-c3coc(C=NO)c3)cc21 -US07868188B2,2,CC(=O)Nc1nc(C)c(-c2cnc(Cl)c(N)c2)s1.O=C=Nc1ccccc1>>CC(=O)Nc1nc(C)c(-c2cnc(Cl)c(NC(=O)Nc3ccccc3)c2)s1 -US07935721B2,3,O=C1N(Cc2ccccn2)c2cccc(Br)c2C12COc1cc3c(cc12)CCO3.OB(O)c1ccoc1>>O=C1N(Cc2ccccn2)c2cccc(-c3ccoc3)c2C12COc1cc3c(cc12)CCO3 -US20110190316A1,1,N#Cc1ccc(-c2ccc(F)cc2)nc1Cl.N#Cc1ccc(NC2CCCNC2)nc1N>>N#Cc1ccc(NC2CCCN(c3nc(-c4ccc(F)cc4)ccc3C#N)C2)nc1N -US07566712B2,1,CC1CCCN1c1nc(Cl)cc(-c2ccc(F)cc2)n1.COc1ccc(Cl)c(N2CCN[C@H](C)C2)n1>>COc1ccc(Cl)c(N2CCN(c3cc(-c4ccc(F)cc4)nc(N4CCCC4C)n3)C(C)C2)n1 -US20130012703A1,1,C[C@@H](N)c1ccccc1.Clc1nc(Cl)c2scc(Br)c2n1>>C[C@@H](Nc1nc(Cl)nc2c(Br)csc12)c1ccccc1 -US08735436B2,6,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(C)(C)C(=O)OC(C)(C)C>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(C)(C)C(=O)O -US03963717,1,CC(C)I.Nc1cccc2c1CCO2>>CC(C)Nc1cccc2c1CCO2 -US20090054431A1,1,Nc1ccc(O)cc1[N+](=O)[O-].O=Cc1ccc(F)cc1>>Nc1ccc(Oc2ccc(C=O)cc2)cc1[N+](=O)[O-] -US20050228017A1,2,O=C(Cl)CCCCc1ccccc1.OCc1cc(CNCCc2ccccn2)ccc1OCc1ccccc1>>O=C(CCCCc1ccccc1)N(CCc1ccccn1)Cc1ccc(OCc2ccccc2)c(CO)c1 -US20080085886A1,2,CC1(C)OC[C@H](CON)O1.CCOC(=O)c1oc2ccncc2c1Nc1ccc(I)cc1F>>CC1(C)OC[C@H](CONC(=O)c2oc3ccncc3c2Nc2ccc(I)cc2F)O1 -US06040345,2,CC(Oc1c(Cl)cc(N)c(F)c1Cl)C(F)(F)C(F)(F)F.O=C=NC(=O)c1c(F)cccc1F>>CC(Oc1c(Cl)cc(NC(=O)NC(=O)c2c(F)cccc2F)c(F)c1Cl)C(F)(F)C(F)(F)F -US20100272677A1,1,BrCc1ccccc1.CC(C)(C)c1cc(Br)c(O)c(C=O)c1>>CC(C)(C)c1cc(Br)c(OCc2ccccc2)c(C=O)c1 -US20120114765A1,2,NCc1ccc(O)cc1.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>O=C(NCc1ccc(O)cc1)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 -US20140243310A1,1,C[C@@H](CO)NC(=O)OC(C)(C)C.O=[N+]([O-])c1cnc(Cl)nc1OCc1ccccc1>>C[C@@H](COc1ncc([N+](=O)[O-])c(OCc2ccccc2)n1)NC(=O)OC(C)(C)C -US05262415,2,CC(=O)Nc1ccc(N)cn1.CC(N=C=S)C(C)(C)C>>CC(=O)Nc1ccc(NC(=S)NC(C)C(C)(C)C)cn1 -US07105671B2,2,CS(=O)(=O)c1ccc(C(CC2CCCCO2)C(=O)O)cc1C(F)(F)F.Nc1cnccn1>>CS(=O)(=O)c1ccc(C(CC2CCCCO2)C(=O)Nc2cnccn2)cc1C(F)(F)F -US08022192B2,2,CC(=O)OC(C)=O.Cc1[nH][nH]c(=O)c1Cc1ccccc1>>CC(=O)n1[nH]c(=O)c(Cc2ccccc2)c1C -US07241798B2,1,CC(C)(C)OC(=O)N1C[C@H]2C[C@@]2(CO)[C@@H]1c1ccccc1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CC2CC2(CN2C(=O)c3ccccc3C2=O)C1c1ccccc1 -US20110245264A1,6,CC[C@H](C)COc1ccc([C@H](CN2C(=O)c3ccccc3C2=O)NC(=O)[C@H]2C[C@@H]2c2cccs2)c(C)c1>>CC[C@H](C)COc1ccc([C@H](CN)NC(=O)[C@H]2C[C@@H]2c2cccs2)c(C)c1 -US20100227856A1,2,CC(C)C[C@H](N)C(=O)NCC1CCCCN1C(=O)OC(C)(C)C.O=C(O)c1cc2ccccc2s1>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCC1CCCCN1C(=O)OC(C)(C)C -US04348399,2,CCCCCCCCCCCCCCCCNc1ccc(CCC(=O)O)cc1.OCCCO>>CCCCCCCCCCCCCCCCNc1ccc(CCC(=O)OCCCO)cc1 -US06350761B1,3,COc1ccc(COc2ccc(C#N)cc2C=O)cc1.O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1ccc(COc2ccc(C#N)cc2C=CC=O)cc1 -US08609669B2,2,CC(C)(C)c1c(N)nn2cccnc12.O=C(O)Cc1ccc(C(F)(F)F)cc1>>CC(C)(C)c1c(NC(=O)Cc2ccc(C(F)(F)F)cc2)nn2cccnc12 -US08349836B2,1,NCc1cccc(-n2cccc2)c1.O=c1[nH]nc(Cl)c2cc(Br)ccc12>>O=c1[nH]nc(Cl)c2cc(NCc3cccc(-n4cccc4)c3)ccc12 -US20110092553A1,3,COC(=O)c1cccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(Br)cc2)c1.COc1cc(B(O)O)ccc1NC(=O)OC(C)(C)C>>COC(=O)c1cccc(Cn2cc(-c3ccc(Cl)cc3Cl)nc2/C=C/c2ccc(-c3ccc(NC(=O)OC(C)(C)C)c(OC)c3)cc2)c1 -US07034015B2,1,CCCC[Sn](/C=C/CBr)(CCCC)CCCC.OCCNCCO>>CCCC[Sn](/C=C/CN(CCO)CCO)(CCCC)CCCC -US20110244481A1,2,CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(Br)n2)cc1.CC(C)(C)[Si](C)(C)Oc1ccc(CC(=O)Cl)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc(CC(=O)Nc2ncc(-c3ccc(O[Si](C)(C)C(C)(C)C)cc3)nc2Br)cc1 -US09000184B2,3,CC1(C)OB(c2cc(Cl)cc(C#N)c2)OC1(C)C.CC1=NC2(N=C1N)c1cc(Br)ccc1CCC21CC1>>CC1=NC2(N=C1N)c1cc(-c3cc(Cl)cc(C#N)c3)ccc1CCC21CC1 -US20110124875A1,2,N#Cc1cc(Cl)ccc1N.O=C(Cl)Oc1ccccc1>>N#Cc1cc(Cl)ccc1NC(=O)Oc1ccccc1 -US20090030041A1,6,CC(C)(C)OC(=O)Nc1cccc(NC2CCN(Cc3ccccc3)CC2)c1>>CC(C)(C)OC(=O)Nc1cccc(NC2CCNCC2)c1 -US05314900,2,Cc1ccc(S(=O)(=O)Cl)cc1.OCc1ccc(F)c(Cl)c1>>Cc1ccc(S(=O)(=O)OCc2ccc(F)c(Cl)c2)cc1 -US20130274469A1,2,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.NC1CCCC1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCC2)cn1 -US20090062297A1,6,CNC(=O)C(C)(O)c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2NC(=O)OC(C)(C)C)cc1>>CNC(=O)C(C)(O)c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 -US06946491B2,7,Cc1cccc(C)c1COc1cccc(C(=O)CCC(=O)O)c1>>Cc1cccc(C)c1COc1cccc(CCCC(=O)O)c1 -US06534546B1,1,CC(C)(C)OC(=O)N(Cc1cc([N+](=O)[O-])ccc1F)C(=O)OC(C)(C)C.CN>>CNc1ccc([N+](=O)[O-])cc1CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C -US20020004494A1,6,COC(CCCN1CCN(C(=O)OC(C)(C)C)CCC1=O)OC>>CC(C)(C)OC(=O)N1CCC(=O)N(CCCC=O)CC1 -US08551984B2,9,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.FC(F)(F)c1ccnc(Nc2cccc(Br)c2)n1>>CC1(C)OB(c2cccc(Nc3nccc(C(F)(F)F)n3)c2)OC1(C)C -US20060293352A1,6,COc1cc(F)c(F)cc1OC>>COc1cc(F)c(F)cc1O -US06329380B1,2,CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CCCNC1.CN(C)CC(=O)O>>CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CCCN(C(=O)CN(C)C)C1 -US05614541,3,O=C1CSC(=S)N1.O=Cc1cc(O)c(O)c([N+](=O)[O-])c1>>O=C1NC(=S)SC1=Cc1cc(O)c(O)c([N+](=O)[O-])c1 -US20020007074A1,7,COc1cc2c(c(C)c1C)C(=O)CC2c1c[nH]cn1>>COc1cc2c(c(C)c1C)C(O)CC2c1c[nH]cn1 -US20080233127A1,1,C1COCCN1.CC(C)(C)OC(=O)N1CCC(n2cnc3c(Cl)nc(Cl)nc32)CC1>>CC(C)(C)OC(=O)N1CCC(n2cnc3c(N4CCOCC4)nc(Cl)nc32)CC1 -US20060004197A1,1,Cc1ccc(C(=O)Nc2cc(F)c([N+](=O)[O-])cc2NC(=O)c2ccc(C)cc2)cc1.Sc1ccc(Cl)cc1>>Cc1ccc(C(=O)Nc2cc(Sc3ccc(Cl)cc3)c([N+](=O)[O-])cc2NC(=O)c2ccc(C)cc2)cc1 -US05559113,1,COC(=O)c1ccc(Cl)nc1.NCCc1c[nH]cn1>>COC(=O)c1ccc(NCCc2c[nH]cn2)nc1 -US20150065482A1,3,C#C[C@]1(O)CCN(C)C1=O.COC(=O)c1nn(-c2cccc(I)c2)c2cnccc12>>COC(=O)c1nn(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)c2cnccc12 -US04816452,1,ClCCl.O=C(CNC(=O)OCc1ccc([N+](=O)[O-])cc1)Nc1ccccc1C(=O)O>>O=C(CNC(=O)OCc1ccc([N+](=O)[O-])cc1)Nc1ccccc1C(=O)OCCl -US06211198B1,7,N#CCCN1CCC(O)(c2ccccc2)CC1>>NCCCN1CCC(O)(c2ccccc2)CC1 -US07572809B2,3,Cc1cc(Nc2cc3ccccc3c(Cl)n2)n[nH]1.OB(O)c1ccc2ccccc2c1>>Cc1cc(Nc2cc3ccccc3c(-c3ccc4ccccc4c3)n2)n[nH]1 -US06352982B1,3,CC(C)(C)OC(=O)Nc1cccc(Br)c1.CON(C)C(=O)c1cc(Cl)ccc1N>>CC(C)(C)OC(=O)Nc1cccc(C(=O)c2cc(Cl)ccc2N)c1 -US20110245242A1,7,O=C1CCCN1c1cc([N+](=O)[O-])ccc1F>>Nc1ccc(F)c(N2CCCC2=O)c1 -US04818756,1,O=S1(=O)c2ccccc2S(=O)(=O)N1CCCCBr.c1cnc(N2CCNCC2)nc1>>O=S1(=O)c2ccccc2S(=O)(=O)N1CCCCN1CCN(c2ncccn2)CC1 -US20100234616A1,4,C#CC(=O)O.[N-]=[N+]=NCc1c(F)cccc1F>>O=C(O)c1cn(Cc2c(F)cccc2F)nn1 -US20090281100A1,1,C1COCCN1.Nc1cc(Cl)ccc1[N+](=O)[O-]>>Nc1cc(N2CCOCC2)ccc1[N+](=O)[O-] -US06995182B2,7,COC(=O)CC[C@H]1CC[C@@H](c2ccc(F)cc2)N1S(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)N2[C@@H](CCCO)CC[C@@H]2c2ccc(F)cc2)cc1 -US20060100201A1,2,CC1CCN(c2cc(N3CCNCC3)ccc2NC(=O)c2ccc(C#N)o2)CC1.CS(=O)(=O)Cl>>CC1CCN(c2cc(N3CCN(S(C)(=O)=O)CC3)ccc2NC(=O)c2ccc(C#N)o2)CC1 -US08481749B2,2,Cc1c(C(=O)O)cccc1S(C)(=O)=O.Cn1ncnc1[NH3+]>>Cc1c(C(=O)Nc2ncnn2C)cccc1S(C)(=O)=O -US20150252044A1,3,NC(=O)c1ccc2cncc(Br)c2n1.OB(O)c1ccc(OC(F)(F)F)cc1>>NC(=O)c1ccc2cncc(-c3ccc(OC(F)(F)F)cc3)c2n1 -US20040044008A1,1,N#Cc1cccc(CBr)c1.O=C(Nc1cccc(N2CCNCC2)c1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>N#Cc1cccc(CN2CCN(c3cccc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)c3)CC2)c1 -US07790715B2,1,CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCOc3cc(F)ccc3F)cc2)C(O)C1.COCCCN1C(=O)COc2ccc(CCl)cc21>>COCCCN1C(=O)COc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCCOc4cc(F)ccc4F)cc3)cc21 -US20020173665A1,3,O=C(O)c1cc(C(=O)O)c(C(=O)N(Cc2cccc(Br)c2)[C@H]2CCCc3ccccc32)cc1C(=O)O.O=[N+]([O-])c1cccc(B(O)O)c1>>O=C(O)c1cc(C(=O)O)c(C(=O)N(Cc2cccc(-c3cccc([N+](=O)[O-])c3)c2)[C@H]2CCCc3ccccc32)cc1C(=O)O -US05719157,1,C1COCCN1.CCOC(=O)c1c(CCl)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1>>CCOC(=O)c1c(CN2CCOCC2)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1 -US07544835B2,2,COC(=O)C(Cc1cccc(CCO)c1)C(=O)OC.O=C=Nc1ccc(C(F)(F)F)cc1>>COC(=O)C(Cc1cccc(CCOC(=O)Nc2ccc(C(F)(F)F)cc2)c1)C(=O)OC -US05635197,1,CN1C(=O)CC[C@]2(C)c3ccc(S)cc3CC[C@@H]12.Cc1cccc2sc(Cl)nc12>>Cc1cccc2sc(Sc3ccc4c(c3)CC[C@H]3N(C)C(=O)CC[C@]43C)nc12 -US20040266758A1,1,CI.COc1cccc2oc(=O)c3c4c(ccc3c12)NC(C)(C)C(=O)N4>>COc1cccc2oc(=O)c3c4c(ccc3c12)NC(C)(C)C(=O)N4C -US20130018033A1,9,CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)c2cc(C)cc3c(Cl)ncnc23)c1F.N>>CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)c2cc(C)cc3c(N)ncnc23)c1F -US04204071,6,CCOC(=O)C(C=Cc1ccc(F)cc1)C(C)C>>CC(C)C(C=Cc1ccc(F)cc1)C(=O)O -US07494992B2,6,Cc1nc2c(c(N3CCCCC3)n1)CCN(Cc1ccccc1)C2>>Cc1nc2c(c(N3CCCCC3)n1)CCNC2 -US20100069629A1,1,C1COCCN1.O=Cc1ccc(F)c(Br)c1>>Fc1ccc(CN2CCOCC2)cc1Br -US20100130489A1,3,NS(=O)(=O)c1cccc(Br)c1.OCCCNc1nc2cc(C(F)(F)F)ccc2n2c(I)cnc12>>NS(=O)(=O)c1cccc(-c2cnc3c(NCCCO)nc4cc(C(F)(F)F)ccc4n23)c1 -US07803833B2,6,COC(=O)[C@]1(C)CC[C@H](c2ccc(OCc3ccccc3F)c(OC)c2)N1C(=O)OC(C)(C)C>>COc1cc([C@H]2CC[C@@](C)(C(=O)O)N2C(=O)OC(C)(C)C)ccc1OCc1ccccc1F -US20100075978A1,2,COc1ccc(Oc2ccccc2NS(=O)(=O)c2ccc(C(=O)O)cc2)c(Cl)c1.NCCN1CCN(c2cnccn2)CC1>>COc1ccc(Oc2ccccc2NS(=O)(=O)c2ccc(C(=O)NCCN3CCN(c4cnccn4)CC3)cc2)c(Cl)c1 -US20030036533A1,9,CCOP(=O)(COCCCl)OCC.[N-]=[N+]=[N-]>>CCOP(=O)(COCCN=[N+]=[N-])OCC -US05998437,1,O=C(Nc1ccc2c(ccn2CCCCl)c1)c1nc2ccc(Cl)cc2n1Cc1ccccc1.c1nnn[nH]1>>O=C(Nc1ccc2c(ccn2CCCn2cnnn2)c1)c1nc2ccc(Cl)cc2n1Cc1ccccc1 -US06924292B2,6,COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc([N+](=O)[O-])c1)=NC(C)(C)C2>>CC1(C)Cc2cc(O)c3c(c2C(c2cccc([N+](=O)[O-])c2)=N1)CC(C)(C)O3 -US20120184542A1,2,CCOCCOc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1.CO>>CCOCCOc1ncc2cc(C(=O)Nc3cc(C(=O)OC)ccc3Cl)c(=O)[nH]c2n1 -US20090099184A1,1,CS(=O)(=O)c1ccccc1O.O=C(NCc1ccc(Cl)cc1Cl)c1ccc(F)nc1>>CS(=O)(=O)c1ccccc1Oc1ccc(C(=O)NCc2ccc(Cl)cc2Cl)cn1 -US04749702,1,BrCC1COc2ccccc2O1.CC(=O)NCC1CCNCC1>>CC(=O)NCC1CCN(CC2COc3ccccc3O2)CC1 -US20130324518A1,1,COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CBr)cc3)cccc2C1=O.FC(F)(F)CCNCCC(F)(F)F>>COC(=O)CCC(C(N)=O)N1Cc2c(OCc3ccc(CN(CCC(F)(F)F)CCC(F)(F)F)cc3)cccc2C1=O -US04536400,1,CCOP(OCC)OCC.COc1ccc(OC(=O)Cl)cc1>>CCOP(=O)(OCC)C(=O)Oc1ccc(OC)cc1 -US20100016311A1,6,COC(=O)c1ccc(/C=C/c2cnc3ccccc3c2)cc1>>O=C(O)c1ccc(/C=C/c2cnc3ccccc3c2)cc1 -US20120289522A1,1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CBr)cc3)cc2)CC1.SCc1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CSCc4ccccc4)cc3)cc2)CC1 -US20050171131A1,1,CS(=O)(=O)c1ccc(C=O)cc1.Nc1ccc(-c2c(N)nc(N)nc2C2CCCC2)cc1>>CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3C3CCCC3)cc2)cc1 -US20030069312A1,9,CCOC(=O)c1ccc(CBr)cc1Cl.[C-]#N>>CCOC(=O)c1ccc(CC#N)cc1Cl -US07745642B2,2,Cc1cccc(C)c1C(=O)Cl.NC(c1ccccc1)C1(N(Cc2ccccc2)Cc2ccccc2)CCCC1>>Cc1cccc(C)c1C(=O)NC(c1ccccc1)C1(N(Cc2ccccc2)Cc2ccccc2)CCCC1 -US20110263658A1,6,COCCCc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)cc1C(=O)OC>>COCCCc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)cc1C(=O)O -US06733883B2,2,O=C(O)Cc1cccc2ccccc12.OCCOCCO>>O=C(Cc1cccc2ccccc12)OCCOCCO -US20110166146A1,1,CCOC(=O)c1cc2ccccc2[nH]1.ClCc1c(-c2ccc(Cl)cc2)nc2ccccn12>>CCOC(=O)c1cc2ccccc2n1Cc1c(-c2ccc(Cl)cc2)nc2ccccn12 -US20030158185A1,2,CNOC.O=C(O)c1ccno1>>CON(C)C(=O)c1ccno1 -US20120165304A1,1,CC(C)(C)OC(=O)N1CCc2nc3ccnn3c(N3CC[C@H]3CO)c2CC1.CI>>COC[C@@H]1CCN1c1c2c(nc3ccnn13)CCN(C(=O)OC(C)(C)C)CC2 -US20140112945A1,2,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.COc1ccc(C2=NN(C3CCNCC3)C(=O)C(C)(C)C2)c2c1OC(C)(C)C2>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccccc4)NC(=O)OC(C)(C)C)CC3)C(=O)C(C)(C)C2)c2c1OC(C)(C)C2 -US08530461B2,6,CCOC(=O)c1sc(NC(C)=O)nc1-c1ccccc1>>CC(=O)Nc1nc(-c2ccccc2)c(C(=O)O)s1 -US20120208798A1,2,CC(=O)OC(C)=O.CCOC(=O)c1cn(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3)cn1>>CCOC(=O)c1cn(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)cn1 -US20150166558A1,6,CCOC(=O)CCCNc1cccc(C(Cn2c(=O)c3c(n(Cc4c(F)cccc4C(F)(F)F)c2=O)COC32CCN(Cc3ccc(C(F)(F)F)o3)CC2)NC(=O)OC(C)(C)C)c1>>CCOC(=O)CCCNc1cccc(C(N)Cn2c(=O)c3c(n(Cc4c(F)cccc4C(F)(F)F)c2=O)COC32CCN(Cc3ccc(C(F)(F)F)o3)CC2)c1 -US20020032207A1,6,CCOC(=O)C1CCC(Cc2nc3ccccc3c(=O)[nH]2)CC1>>O=C(O)C1CCC(Cc2nc3ccccc3c(=O)[nH]2)CC1 -US20060074102A1,6,CC(C)(C)OC(=O)Nc1cc2c(Oc3ccc(I)cc3)cncc2s1>>Nc1cc2c(Oc3ccc(I)cc3)cncc2s1 -US20130059834A1,1,CI.Fc1cc2[nH]nc(Br)c2cc1F>>Cn1nc(Br)c2cc(F)c(F)cc21 -US08143263B2,1,COC(=O)[C@@H](O)CO[C@@H](C)CO[Si](C)(C)C(C)(C)C.Clc1cccnc1-n1ncc2c(Cl)ncnc21>>COC(=O)[C@H](CO[C@@H](C)CO[Si](C)(C)C(C)(C)C)Oc1ncnc2c1cnn2-c1ncccc1Cl -US20060142317A1,1,CN1CCc2c(sc3ncn(CCCl)c(=O)c23)C1.Cc1ccc2onc(N3CCNCC3)c2c1>>Cc1ccc2onc(N3CCN(CCn4cnc5sc6c(c5c4=O)CCN(C)C6)CC3)c2c1 -US20140038989A1,2,CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)O)c3N2)cc1.Cc1ccc(CN)c(F)c1>>CCc1ccc([C@H]2C[C@@H](C(F)(F)F)n3ncc(C(=O)NCc4ccc(C)cc4F)c3N2)cc1 -US04027040,9,Cc1c(C(=O)O)cccc1C(=O)c1ccc(Cl)cc1>>Cc1c(C=O)cccc1C(=O)c1ccc(Cl)cc1 -US20150148311A1,1,CC(C)(O)C(=O)N1CCN(C2CC2)c2ccccc21.Clc1ccc(Cl)c(CBr)c1>>CC(C)(OCc1cc(Cl)ccc1Cl)C(=O)N1CCN(C2CC2)c2ccccc21 -US20100113780A1,1,CC(C)Oc1ccc(B(O)O)cc1.CCCc1nc[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1ncn(-c2ccc(OC(C)C)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1 -US20090012075A1,6,COc1ccccc1-c1nnc(C(F)(F)c2ccc(C(=O)Nc3nn(-c4ccccc4)cc3NC(=O)OC(C)(C)C)cc2)o1>>COc1ccccc1-c1nnc(C(F)(F)c2ccc(C(=O)Nc3nn(-c4ccccc4)cc3N)cc2)o1 -US06498251B1,1,O=C1Nc2cccc3c2C1(CCCCBr)CCC3.c1ccc(CC2CCNCC2)cc1>>O=C1Nc2cccc3c2C1(CCCCN1CCC(Cc2ccccc2)CC1)CCC3 -US20090111800A1,1,CC(C)I.O=C1C(Cc2ccc(O)cc2Cl)CCN1C1CCc2n[nH]cc2C1>>CC(C)Oc1ccc(CC2CCN(C3CCc4n[nH]cc4C3)C2=O)c(Cl)c1 -US20090143456A1,1,Cc1cc(C)c(S(=O)(=O)NC2(c3ccccc3)CC2)c(C)c1.O=C1c2ccccc2C(=O)N1CCCCBr>>Cc1cc(C)c(S(=O)(=O)N(CCCCN2C(=O)c3ccccc3C2=O)C2(c3ccccc3)CC2)c(C)c1 -US06969711B2,1,CC(C)c1cc(O)cc(C(C)C)c1NC(=O)CBr.OCCN1CCNCC1>>CC(C)c1cc(O)cc(C(C)C)c1NC(=O)CN1CCN(CCO)CC1 -US05138069,7,CCCSc1ncc(C(=O)OCC)n1Cc1ccc(OCc2ccccc2)cc1>>CCCSc1ncc(CO)n1Cc1ccc(OCc2ccccc2)cc1 -US05256789,9,NO.O=C1CCc2ccccc21>>ON=C1CCc2ccccc21 -US08354444B2,6,CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cc(F)cc(Cl)c2)C1(C#N)c1ccc(Cl)cc1F>>CC(C)(C)CC1NC(C(=O)O)C(c2cc(F)cc(Cl)c2)C1(C#N)c1ccc(Cl)cc1F -US04512992,7,CCOC(=O)C(=Cc1ccc(OC)c(OC)c1)C(C)=O>>CCOC(=O)C(Cc1ccc(OC)c(OC)c1)C(C)=O -US20060142585A1,6,CC(C)(C)OC(=O)N1CC[C@H](F)C1>>F[C@H]1CCNC1 -US06251933B1,6,COC(=O)/C=C/c1cccc(NC(=O)c2cccn2C)c1>>Cn1cccc1C(=O)Nc1cccc(/C=C/C(=O)O)c1 -US04021557,1,CN(C)CCCl.CN1C(=O)c2cccnc2Nc2ccccc21>>CN(C)CCN1c2ccccc2N(C)C(=O)c2cccnc21 -US20090042726A1,9,Cc1nn(C)c(C(N)=O)c1C(F)(F)F>>Cc1nn(C)c(C#N)c1C(F)(F)F -US05166430,1,FCCCl.NS(=O)(=O)c1ccccc1S>>NS(=O)(=O)c1ccccc1SCCF -US20050203127A1,6,CC(C)(C)OC(=O)NCc1cccc(-n2nc(C(F)(F)F)cc2C(=O)Nc2ccc(N3CCCC3=N)cc2)c1>>N=C1CCCN1c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cccc(CN)c2)cc1 -US05189053,7,N#CC(N)=C(C#N)N=Cc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1>>N#CC(N)=C(C#N)NCc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1 -US20110059941A1,1,CS(=O)(=O)c1ccc(O)cc1.N#Cc1cc(F)cc(F)c1>>CS(=O)(=O)c1ccc(Oc2cc(F)cc(C#N)c2)cc1 -US08399436B2,1,COc1ccc(CBr)c(C(F)(F)F)c1.O=C(Nc1cc[nH]n1)c1ccccc1F>>COc1ccc(Cn2ccc(NC(=O)c3ccccc3F)n2)c(C(F)(F)F)c1 -US07544690B2,6,CN(C)c1nc(N[C@@H]2CC[C@H](CNC(=O)OCc3ccccc3)CC2)nc2ccccc12>>CN(C)c1nc(NC2CCC(CN)CC2)nc2ccccc12 -US04447259,1,C1CNOC1.CC(Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)C(=O)Cl>>CC(Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)C(=O)N1CCCO1 -US04904655,7,CCOC(=O)CNCCc1c[nH]c2ccccc12>>OCCNCCc1c[nH]c2ccccc12 -US07173051B2,6,CC(C)(C)C[C@H](Nc1nc2ccccc2o1)C(=O)N[C@@H](CC(=O)OC(C)(C)C)CN1CCc2cc(F)ccc21>>CC(C)(C)C[C@H](Nc1nc2ccccc2o1)C(=O)N[C@@H](CC(=O)O)CN1CCc2cc(F)ccc21 -US20150283134A1,2,CS(=O)(=O)c1ccc(Cl)c(C(=O)O)c1.NCC1(c2ccc(F)nc2)CCC(F)(F)CC1>>CS(=O)(=O)c1ccc(Cl)c(C(=O)NCC2(c3ccc(F)nc3)CCC(F)(F)CC2)c1 -US07666888B2,2,Cc1ccc(-c2oncc2C(=O)O)cc1.Fc1ccc(C2=CCNC2)cc1>>Cc1ccc(-c2oncc2C(=O)N2CC=C(c3ccc(F)cc3)C2)cc1 -US08461348B2,4,CCOC(=O)c1cnn(C(C)C(N)=S)c1.O=C(CBr)c1ccc(Cl)c(Cl)c1>>CCOC(=O)c1cnn(C(C)c2nc(-c3ccc(Cl)c(Cl)c3)cs2)c1 -US20120004164A1,2,Cc1nc(N2CCN(Cc3ccc(OC(F)(F)F)cc3)C2=O)sc1C(=O)O.NCCC1CC1>>Cc1nc(N2CCN(Cc3ccc(OC(F)(F)F)cc3)C2=O)sc1C(=O)NCCC1CC1 -US20050131014A1,2,Nc1cccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)c1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1cccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 -US20140288045A1,2,COc1cc(Cl)c(-c2ccc(Cl)cc2)cc1C(=O)O.N#CC1CNCCN1>>COc1cc(Cl)c(-c2ccc(Cl)cc2)cc1C(=O)N1CCNC(C#N)C1 -US20040209921A1,1,Cc1cc(Cl)cnc1CNCCCCN(C)C(=O)OC(C)(C)C.O=Cc1nccc2ccccc12>>Cc1cc(Cl)cnc1CN(CCCCN(C)C(=O)OC(C)(C)C)Cc1nccc2ccccc12 -US20080287466A1,2,NC1=c2ccoc2=NCN1c1ccc(N)cc1.O=C(Cl)C1(c2ccccc2)CC1>>NC1=c2ccoc2=NCN1c1ccc(NC(=O)C2(c3ccccc3)CC2)cc1 -US20080176906A1,7,COC(=O)c1cc(Cn2c(C)c(C#N)c(-c3ccc(C#N)cc3)c2C)ccc1Cl>>Cc1c(C#N)c(-c2ccc(C#N)cc2)c(C)n1Cc1ccc(Cl)c(CO)c1 -US06281227B1,4,C#CCN1CC[C@H](NS(=O)(=O)c2cc3ccc(Cl)cc3s2)C1=O.CC(C)(C)OC(=O)Nc1cnccc1I>>CC(C)(C)OC(=O)n1c(CN2CC[C@H](NS(=O)(=O)c3cc4ccc(Cl)cc4s3)C2=O)cc2ccncc21 -US06218429B1,2,CC(=O)Cl.NCCC1=CCc2ccc3c(c21)CCO3>>CC(=O)NCCC1=CCc2ccc3c(c21)CCO3 -US05599832,9,Cn1c(I)cc2cc(Cl)ccc21>>Cn1ccc2cc(Cl)ccc21 -US06953789B2,6,CC(=O)SC1CCN(Cc2ccc(Oc3ccccc3)cc2)C1=O>>O=C1C(S)CCN1Cc1ccc(Oc2ccccc2)cc1 -US20110053933A1,2,CC(C)[C@H](N)C(=O)N1CCC(Oc2ncc(Cl)cn2)CC1.O=C(O)c1nc2ccccc2nc1O>>CC(C)[C@H](NC(=O)c1nc2ccccc2nc1O)C(=O)N1CCC(Oc2ncc(Cl)cn2)CC1 -US09040516B2,6,Cc1c(-c2ccnn2-c2ccc(C#N)cc2)c(=O)n(CC(=O)OCc2ccccc2)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1c(-c2ccnn2-c2ccc(C#N)cc2)c(=O)n(CC(=O)O)c(=O)n1-c1cccc(C(F)(F)F)c1 -US04849424,1,COc1cc(C)nc(Cl)n1.c1nc[nH]n1>>COc1cc(C)nc(-n2cncn2)n1 -US20130245000A1,2,CCOC(=O)Cl.Nc1ccc2[nH]ccc2c1>>CCOC(=O)Nc1ccc2[nH]ccc2c1 -US20140011800A1,6,CC(C)(C)OC(=O)NC1CN(Cc2ccccc2)CC12CCC2>>CC(C)(C)OC(=O)NC1CNCC12CCC2 -US20040248887A1,2,Cc1cccc(C(=O)N[C@@H](CC(C)C)C(=O)O)c1.NCCO>>Cc1cccc(C(=O)N[C@@H](CC(C)C)C(=O)NCCO)c1 -US20140350011A1,2,CCOC(=O)C(N)CO.O=Cc1ccc(C(=O)O)cc1>>CCOC(=O)C(CO)NC(=O)c1ccc(C=O)cc1 -US20100216821A1,1,Clc1nc2ccccc2[nH]1.O=C1OC2(CCNCC2)CN1c1ccccc1>>O=C1OC2(CCN(c3nc4ccccc4[nH]3)CC2)CN1c1ccccc1 -US08293772B2,1,Cc1ccc(-n2cc(CCO)nn2)cc1C(=O)c1ccc(Br)cc1Cl.Nc1cccc(Cl)c1Cl>>Cc1ccc(-n2cc(CCO)nn2)cc1C(=O)c1ccc(Nc2cccc(Cl)c2Cl)cc1Cl -US07737166B2,1,CN(C)[C@H]1CCNC1.Cc1c(-c2ccccc2)c(F)c2oc(C(C)(C)O)nc2c1C#N>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(C(C)(C)O)nc2c1C#N -US20100113782A1,2,CC(C)(C)c1cccc(NC(=O)c2ccc(N3CCNCC3)cc2)c1.O=C(OCc1ccccc1)[C@@H]1CC[C@@H](C(=O)O)CC1>>CC(C)(C)c1cccc(NC(=O)c2ccc(N3CCN(C(=O)C4CCC(C(=O)O)CC4)CC3)cc2)c1 -US20110166121A1,2,CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(OCCN)nc2s1.CS(=O)(=O)CC(=O)O>>CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(OCCNC(=O)CS(C)(=O)=O)nc2s1 -US20110257151A1,6,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccccc1NC(=O)C1CCC1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1ccccc1NC(=O)C1CCC1 -US20130253186A1,2,CC(=O)Cl.c1ccc2nc(N3CC(Oc4ncncc4C4CCNCC4)C3)ccc2c1>>CC(=O)N1CCC(c2cncnc2OC2CN(c3ccc4ccccc4n3)C2)CC1 -US05912246,1,ClCc1cn2cc(Br)ccc2n1.NC(=O)c1ccc(N2CCNCC2)cc1>>NC(=O)c1ccc(N2CCN(Cc3cn4cc(Br)ccc4n3)CC2)cc1 -US20130253004A1,6,CCOC(=O)CC1(c2ccc(-c3ccc(-c4ccncc4C(O)CCCc4ccccc4)cc3)cc2)CC1>>O=C(O)CC1(c2ccc(-c3ccc(-c4ccncc4C(O)CCCc4ccccc4)cc3)cc2)CC1 -US20150152047A1,2,CCS(=O)(=O)c1ccc(Cl)cc1NN.COc1cc(C(=O)O)ccc1NC1CCN(C(=O)OC(C)(C)C)CC1>>CCS(=O)(=O)c1ccc(Cl)cc1NNC(=O)c1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)c(OC)c1 -US20150038528A1,2,CCOC(=O)C(C)(C)CN.COC(=O)c1nc(C#N)c2cc(Oc3ccc4ccccc4c3)ccc2c1O>>CCOC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(Oc3ccc4ccccc4c3)ccc2c1O -US08471005B2,1,CN1CCN(C)C(c2ccc(N)cc2)C1=O.COc1ccc(-c2ccc3cnc(OS(=O)(=O)C(F)(F)F)nn23)cn1>>COc1ccc(-c2ccc3cnc(Nc4ccc(C5C(=O)N(C)CCN5C)cc4)nn23)cn1 -US20100041891A1,2,CNOC.O=C(O)c1cc2cccc(Br)c2s1>>CON(C)C(=O)c1cc2cccc(Br)c2s1 -US20110160202A1,1,C1COCCN1.O=C(c1ccc(Oc2nccnc2Cl)cc1)c1nc2ccccc2[nH]1>>O=C(c1ccc(Oc2nccnc2N2CCOCC2)cc1)c1nc2ccccc2[nH]1 -US20050038019A1,1,CC(C)CI.Oc1ccccc1Br>>CC(C)COc1ccccc1Br -US20090111776A1,6,CCN1CCCC1C(=O)OCc1ccccc1>>CCN1CCC[C@H]1C(=O)O -US20150284321A1,2,Cc1ccccc1S(=O)(=O)Cl.Nc1ccccc1NC(=O)Nc1ccccc1>>Cc1ccccc1S(=O)(=O)Nc1ccccc1NC(=O)Nc1ccccc1 -US20070219182A1,1,C[C@H]1CNCCN1.O=C1CCC(=O)N(CCCCCl)c2ccccc21>>C[C@H]1CN(CCCCN2C(=O)CCC(=O)c3ccccc32)CCN1 -US20140094462A1,2,C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)O.OC[C@@H]1CCCN1>>C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1CO -US20150031674A1,1,CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)[nH]c2n1.O=C1OCCN1CCCl>>CSc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CCN3CCOC3=O)c2n1 -US04636509,1,CS(=O)c1ccc(C(=O)CBr)cc1.O=c1ncc(Cl)c[nH]1>>CS(=O)c1ccc(C(=O)Cn2cc(Cl)cnc2=O)cc1 -US05061720,1,CCOC(=O)CCCCCBr.O=C1NC(=O)c2ccccc21>>CCOC(=O)CCCCCN1C(=O)c2ccccc2C1=O -US20130303507A1,1,COC[C@@H](C)N[C@@H]1CC[C@@H](N)CC1.Clc1cc(Cl)ncn1>>COC[C@@H](C)N[C@@H]1CC[C@@H](Nc2cc(Cl)ncn2)CC1 -US20140163026A1,1,CCCC[Sn](Cl)(CCCC)CCCC.Cc1nccs1>>CCCC[Sn](CCCC)(CCCC)c1cnc(C)s1 -US20150225371A1,1,Cc1cc(-c2cn(CC3CN(C)C3)c(C3CCNCC3)n2)ccc1F.Nc1ncnc(Cl)c1Cl>>Cc1cc(-c2cn(CC3CN(C)C3)c(C3CCN(c4ncnc(N)c4Cl)CC3)n2)ccc1F -US03966811,1,CCCc1ccc(F)cc1N.O=CCCl>>CCCc1ccc(F)cc1NCC=O -US04259336,2,CCCc1cnc(N)s1.COC(=O)C1=C(O)c2sc3ccccc3c2S(=O)(=O)N1C>>CCCc1cnc(NC(=O)C2=C(O)c3sc4ccccc4c3S(=O)(=O)N2C)s1 -US06034099,9,CCc1ccccc1NC=C1C(=O)N(c2ccc(C(=O)O)cc2)N=C1C.N>>CCc1ccccc1NC=C1C(=O)N(c2ccc(C(N)=O)cc2)N=C1C -US20040259912A1,1,CC(C)c1ccc(CBr)cc1.COC(=O)c1cc([N+](=O)[O-])ccc1O>>COC(=O)c1cc([N+](=O)[O-])ccc1OCc1ccc(C(C)C)cc1 -US07256198B2,6,COC[C@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C1(OCCCO1)C1=NCC(C)(C)CN12>>COC[C@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C1=NCC(C)(C)CN12 -US07985755B2,6,CC(C)(C)OC(=O)N1CCN(CCOc2cccc3nc(N)nc(N)c23)CC1>>Nc1nc(N)c2c(OCCN3CCNCC3)cccc2n1 -US08367831B2,1,CC(C)(C)OC(=O)Nc1cnc2ccc(=O)n(CC3OCCO3)c2c1.CI>>CN(C(=O)OC(C)(C)C)c1cnc2ccc(=O)n(CC3OCCO3)c2c1 -US20070049607A1,1,CNC(=O)C(F)(F)F.Nc1nc(-c2ccco2)c2nnn(Cc3cccc(CBr)n3)c2n1>>CN(Cc1cccc(Cn2nnc3c(-c4ccco4)nc(N)nc32)n1)C(=O)C(F)(F)F -US20120184546A1,6,COc1cc(Cc2nc3cc(NCCCO)ccc3c3nc(N)nn23)ccc1OCc1ccccc1>>COc1cc(Cc2nc3cc(NCCCO)ccc3c3nc(N)nn23)ccc1O -US20100273770A1,6,CC(C)Oc1ncc(-c2nc(-c3cccc4c3OCCN(C(=O)OC(C)(C)C)C4CCCC(=O)O)no2)cc1Cl>>CC(C)Oc1ncc(-c2nc(-c3cccc4c3OCCNC4CCCC(=O)O)no2)cc1Cl -US06790854B2,1,BrCc1ccccc1.OCCNCCO>>OCCN(CCO)Cc1ccccc1 -US20110294842A9,6,COCOc1cnc(OC)cc1C1(O)C(=O)N(C(c2ccccc2)c2ccccc2)c2ccccc21>>COc1cc(C2(O)C(=O)N(C(c3ccccc3)c3ccccc3)c3ccccc32)c(O)cn1 -US07323465B2,1,CCS(=O)(=O)Nc1ncnc(OCCO)c1-c1ccc(C)cc1.Clc1ncc(Br)cn1>>CCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(C)cc1 -US04898871,2,CC(C)CCN.COc1ccc2ccc(N3C(=O)c4ccccc4C3OCC(=O)O)nc2n1>>COc1ccc2ccc(N3C(=O)c4ccccc4C3OCC(=O)NCCC(C)C)nc2n1 -US20020134517A1,1,CO.Oc1ccccc1O>>COc1ccccc1O -US20100068197A1,1,CNc1ccc(OC)cc1.Cc1ccc2nc(Cl)nc(Cl)c2c1>>COc1ccc(N(C)c2nc(Cl)nc3ccc(C)cc23)cc1 -US07989477B2,6,CC(=O)Nc1ccc(Oc2ccnc(Nc3ccc(F)cc3)n2)c(F)c1>>Nc1ccc(Oc2ccnc(Nc3ccc(F)cc3)n2)c(F)c1 -US09096592B2,1,C1CNC1.Cn1c(=O)[nH]c2nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc(I)c21>>Cn1c(=O)[nH]c2nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc(N3CCC3)c21 -US20120053168A1,6,CC(C)(C)OC(=O)N1CCc2cc3nccnc3cc2CC1>>c1cnc2cc3c(cc2n1)CCNCC3 -US06632816B1,1,CC(=O)OCCBr.CC(C)CN([C@H](CO)CCCNC(=O)[C@@H](N)Cc1cccc2ccccc12)S(=O)(=O)c1ccc(N)cc1>>CC(=O)OCCN[C@@H](Cc1cccc2ccccc12)C(=O)NCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 -US07642276B2,1,BrCC1CC1.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2[nH]ncc2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2CC2CC2)c1 -US20050065135A1,1,C1CCNCC1.C=C[C@@]12CCc3cc(O)ccc3[C@H]1[C@@H](CCCCCBr)C[C@@]1(C)[C@H]2CC[C@@H]1O>>C=C[C@@]12CCc3cc(O)ccc3[C@H]1[C@@H](CCCCCN1CCCCC1)C[C@@]1(C)[C@H]2CC[C@@H]1O -US04562199,6,CCOC(=O)/C=C/c1ccc(Cn2ccnc2)c(Cl)c1>>O=C(O)/C=C/c1ccc(Cn2ccnc2)c(Cl)c1 -US04151302,2,CC(CC(=O)O)c1ccc(-c2ccc(F)cc2F)cc1.CCCCO>>CCCCOC(=O)CC(C)c1ccc(-c2ccc(F)cc2F)cc1 -US20140329807A1,1,FC(F)(F)c1cccc(-c2cnc3ccc(Cl)nn23)c1.N#C[C@H]1CC[C@H](N)CC1>>N#C[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(C(F)(F)F)c4)n3n2)CC1 -US20150166549A1,6,CC(c1oc(=O)c2ccccc2c1C1=CCN(C(=O)OC(C)(C)C)CC1)n1nc(I)c2c(N)ncnc21>>CC(c1oc(=O)c2ccccc2c1C1=CCNCC1)n1nc(I)c2c(N)ncnc21 -US05505931,9,NCc1ccoc1.S=C(Cl)Cl>>S=C=NCc1ccoc1 -US07563815B2,6,COC(=O)c1ccc(CN(c2nc3cc(OC)ccc3n2C)C2CCC(C(C)(C)C)CC2)cc1>>COC(=O)c1ccc(CN(c2nc3cc(O)ccc3n2C)C2CCC(C(C)(C)C)CC2)cc1 -US20100113422A1,6,Clc1cccc(Cc2ncc3c(n2)CCN(Cc2ccccc2)CC3)c1>>Clc1cccc(Cc2ncc3c(n2)CCNCC3)c1 -US06903128B2,9,C=CCOC(=O)NC(Cc1cc(C2CCCN2C(=O)OC(C)(C)C)no1)(C(=O)OCC)C(=O)OCC>>C=CCOC(=O)NC(Cc1cc(C2CCCN2C(=O)OC(C)(C)C)no1)C(=O)OCC -US08802712B2,6,COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccccc1>>COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1O -US20080171756A1,6,CCOC(=O)CNC(=O)c1c(O)nc(-c2cccc(Br)c2)n(Cc2ccccc2)c1=O>>O=C(O)CNC(=O)c1c(O)nc(-c2cccc(Br)c2)n(Cc2ccccc2)c1=O -US20120184542A1,6,CN1CCN(CCCNc2ncc3cc(C(=O)Nc4cc(C(=O)NC(CCNC(=O)OC(C)(C)C)c5ccccc5)ccc4Cl)c(=O)[nH]c3n2)CC1>>CN1CCN(CCCNc2ncc3cc(C(=O)Nc4cc(C(=O)NC(CCN)c5ccccc5)ccc4Cl)c(=O)[nH]c3n2)CC1 -US05510504,9,CC1(C)C2CC[C@@]1(C)C(=O)C2.NO>>CC1(C)C2CC[C@@]1(C)C(=NO)C2 -US06624159B2,6,CCOC(=O)c1cn(N(C)C(=O)OC(C)(C)C)c2c(F)cc(I)cc2c1=O>>CCOC(=O)c1cn(NC)c2c(F)cc(I)cc2c1=O -US09045486B2,6,CN1CCn2c(CC3(n4ccc5cccnc54)CCCC3)nc(=O)c(OCc3ccccc3)c2C1=O>>CN1CCn2c(CC3(n4ccc5cccnc54)CCCC3)nc(=O)c(O)c2C1=O -US06593335B1,6,CSc1cc(C2OCCO2)ccc1C>>CSc1cc(C=O)ccc1C -US07473703B2,9,COCCn1cccc1C(C)(O)c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1>>COCCn1cccc1C(C)c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1 -US08759535B2,6,Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)N[C@@H]3CCN(C(=O)OC(C)(C)C)C3)ccc21>>Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)N[C@@H]3CCNC3)ccc21 -US06638929B2,6,COc1ccc2cc3ncc(C#N)c(Nc4ccc(Cl)cc4Cl)c3cc2c1>>N#Cc1cnc2cc3ccc(O)cc3cc2c1Nc1ccc(Cl)cc1Cl -US20040171604A1,6,COC(=O)c1cncn1Cc1cc(-c2ccc(Cl)s2)on1>>O=C(O)c1cncn1Cc1cc(-c2ccc(Cl)s2)on1 -US20060154955A1,6,O=C(NC1Cc2nc(-c3ccccc3)ccc2N(Cc2ccccc2)C1=O)OCc1ccccc1>>NC1Cc2nc(-c3ccccc3)ccc2N(Cc2ccccc2)C1=O -US07737166B2,6,Cc1c(NC(=O)OC(C)(C)C)c(F)c2oc(C3CC3)nc2c1C#N>>Cc1c(N)c(F)c2oc(C3CC3)nc2c1C#N -US20080167307A1,6,CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ncc(C(=O)OC)cc1Cl>>CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ncc(C(=O)O)cc1Cl -US20090054435A1,6,COCOc1cc(OC)cc(C)c1C(=O)c1ccc(OCc2ccccc2)cc1>>COCOc1cc(OC)cc(C)c1C(=O)c1ccc(O)cc1 -US09051281B2,6,COC(=O)c1nnn(Cc2ccc(Cl)c(Cl)c2)c1C>>Cc1c(C(=O)O)nnn1Cc1ccc(Cl)c(Cl)c1 -US20120251545A1,6,COc1ccc2c(c1)CNC2>>Oc1ccc2c(c1)CNC2 -US08288371B2,6,CC(C)(C)OC(=O)N1CCC[C@@H]1c1nncn1Cc1ccc(Cl)cc1>>Clc1ccc(Cn2cnnc2[C@H]2CCCN2)cc1 -US20140349990A1,9,Cc1cc(Cl)nnc1Cl.NN>>Cc1cc(Cl)nnc1NN -US20150148349A1,6,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)NC1CCCCC1>>O=C(NC1CCCCC1)[C@@H]1C[C@H]2C[C@H]2N1 -US08916560B2,6,COC[C@H]1CCCN1c1nc2cc(C(=O)OC)ccc2nc1-c1ccccc1>>COC[C@H]1CCCN1c1nc2cc(C(=O)O)ccc2nc1-c1ccccc1 -US20070249705A1,6,CN(C(=O)C(F)(F)F)C1CCc2cc(N3CC[C@H](NC(=O)OC(C)(C)C)C3=O)ccc21>>CN(C(=O)C(F)(F)F)C1CCc2cc(N3CC[C@H](N)C3=O)ccc21 -US20070003539A1,6,COc1ccc(-n2nc(C)cc2C)c(CN)c1>>Cc1cc(C)n(-c2ccc(O)cc2CN)n1 -US06989383B1,6,CC(C)(C)OC(=O)N1CCN(c2cccc(Cl)c2)C(=O)C1>>O=C1CNCCN1c1cccc(Cl)c1 -US07547680B2,6,OC[C@H]1O[C@@H](n2c(NCc3ccc(-c4ccccc4)c(OCCCCOCc4ccccc4)c3)nc3ccccc32)[C@H](O)[C@@H]1O>>OCCCCOc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 -US08252723B2,6,COC(=O)Cc1c(C)nn(-c2cnccc2C)c1-c1ccccc1>>Cc1ccncc1-n1nc(C)c(CC(=O)O)c1-c1ccccc1 -US20150175602A1,6,CC(C)Nc1nc2c(nc1N1CCC(S(=O)(=O)c3cccc(F)c3)CC1)CN(Cc1ccccc1)CC2>>CC(C)Nc1nc2c(nc1N1CCC(S(=O)(=O)c3cccc(F)c3)CC1)CNCC2 -US07759373B2,6,CCC(NC(=O)OC(C)(C)C)C(=O)c1cccnc1>>CCC(N)C(=O)c1cccnc1 -US06653334B1,6,C=CCOC(=O)c1cccc(OC(C)(C)C(=O)OC(C)(C)C)c1>>C=CCOC(=O)c1cccc(OC(C)(C)C(=O)O)c1 -US05037824,9,NC(=O)c1cccc(C=CC(=O)c2ccccc2)n1>>N#Cc1cccc(C=CC(=O)c2ccccc2)n1 -US20150051197A1,6,CC(C)(C)NS(=O)(=O)CCNC(=O)OCc1ccccc1>>CC(C)(C)NS(=O)(=O)CCN -US20040002524A1,6,COc1ccc(-n2c(-c3ccc[nH]3)nc3ccccc32)cc1>>Oc1ccc(-n2c(-c3ccc[nH]3)nc3ccccc32)cc1 -US05185351,6,CCCCc1ncc(/C=C(\Cc2cccs2)C(=O)OC)n1Cc1c(F)cccc1Cl>>CCCCc1ncc(/C=C(\Cc2cccs2)C(=O)O)n1Cc1c(F)cccc1Cl -US20120101147A1,6,C#Cc1ccc(NC(=O)OC(C)(C)C)c(NC(=O)/C=C/c2ccc(NC(C)=O)cc2)c1>>C#Cc1ccc(N)c(NC(=O)/C=C/c2ccc(NC(C)=O)cc2)c1 -US20060211724A1,6,CC1(c2cccnc2C(O)=C2CC(=O)N(Cc3ccc4c(c3)OCO4)C2=O)OCCO1>>CC(=O)c1cccnc1C(O)=C1CC(=O)N(Cc2ccc3c(c2)OCO3)C1=O -US20090149469A1,6,COC(=O)c1cccc(OCc2ccccc2)c1>>O=C(O)c1cccc(OCc2ccccc2)c1 -US20070225271A1,6,CC(C)(C)OC(=O)N1CCC(Nc2nc(-c3ccccc3)c3nccnc3n2)CC1>>c1ccc(-c2nc(NC3CCNCC3)nc3nccnc23)cc1 -US20050010052A1,6,CC(C)(C)OC(=O)NCCCNc1nccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1Cl>>NCCCNc1nccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1Cl -US08648074B2,9,N#C[Cu].O=S(=O)(c1cc(C(F)(F)F)ccc1Br)N1CCN2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2C1>>N#Cc1ccc(C(F)(F)F)cc1S(=O)(=O)N1CCN2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2C1 -US20120309739A1,6,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncc(-c5ccccn5)nc4c3-c3ccccc3)cc2)CCC1>>NC1(c2ccc(-c3oc4ncc(-c5ccccn5)nc4c3-c3ccccc3)cc2)CCC1 -US20150126449A1,6,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(-c5ccc(C(F)(F)F)cc5)cccc4nn23)CC1>>O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccc(C(F)(F)F)cc4)c3c2[nH]1 -US07855292B2,6,COC(=O)c1ccc(C)cc1NS(=O)(=O)c1cccc2nsnc12>>Cc1ccc(C(=O)O)c(NS(=O)(=O)c2cccc3nsnc23)c1 -US20090247526A1,6,Brc1cnc(Nc2nc(CCc3ccccc3)cs2)cc1OCc1ccccc1>>Oc1cc(Nc2nc(CCc3ccccc3)cs2)ncc1Br -US20040110945A1,6,COC(=O)Cc1ccc2nc(-c3cccc4ccccc34)oc2c1>>O=C(O)Cc1ccc2nc(-c3cccc4ccccc34)oc2c1 -US20140275562A1,6,COC(=O)c1ccc(-c2ncn(-c3ccc(OC(F)(F)C(F)(F)F)cc3)n2)cc1>>O=C(O)c1ccc(-c2ncn(-c3ccc(OC(F)(F)C(F)(F)F)cc3)n2)cc1 -US05041453,9,NC(=O)c1nc2cccc([N+](=O)[O-])c2o1>>N#Cc1nc2cccc([N+](=O)[O-])c2o1 -US08765730B2,9,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(C(=O)NC[C@@H](O)CO)cc1.NO>>Cc1cc(Cl)ccc1C(C/C(=N\O)c1ccc(=O)n(C)c1)c1ccc(C(=O)NC[C@@H](O)CO)cc1 -US08765730B2,9,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(OS(C)(=O)=O)c(F)c1.NO>>Cc1cc(Cl)ccc1C(C/C(=N\O)c1ccc(=O)n(C)c1)c1ccc(OS(C)(=O)=O)c(F)c1 -US20100312000A1,9,Nc1ccc(CC(=O)O)cc1.S=C=S>>O=C(O)Cc1ccc(N=C=S)cc1 -US05332757,9,COC1(c2cnc(OCc3ccc(C(C)=O)cc3)s2)CCOCC1.NO>>COC1(c2cnc(OCc3ccc(/C(C)=N/O)cc3)s2)CCOCC1 -US04851418,9,[N-]=[N+]=N[C@H]1CCN(C(=O)OCc2ccccc2)C1>>N[C@H]1CCN(C(=O)OCc2ccccc2)C1 -US06265432B1,9,O=C(O)CCC(=NO)c1ccc(-c2ccc(Cl)cc2)c(F)c1>>O=C(O)CCC(=NO)c1ccc(-c2ccccc2)c(F)c1 -US20120065257A1,9,BrCC1COc2ccccc2O1.[C-]#N>>N#CCC1COc2ccccc2O1 -US20090028925A1,9,BrC(Br)(Br)Br.COCOc1ccc(Cc2c(C)cc(CO)cc2C)cc1Cc1ccc(F)cc1>>COCOc1ccc(Cc2c(C)cc(CBr)cc2C)cc1Cc1ccc(F)cc1 -US20140194411A1,9,CCOC(=O)N1CCc2ccc3c(c2CC1)C(O)(C1CC1)CC3>>CCOC(=O)N1CCc2ccc3c(c2CC1)C(C1CC1)CC3 -US20090149445A1,9,Brc1cccc(C=C2c3ccccc3CCc3ccccc32)c1.N#C[Cu]>>N#Cc1cccc(C=C2c3ccccc3CCc3ccccc32)c1 -US08710243B2,9,Cc1noc(C)c1-c1c(-c2ccc(O)cc2)c2ccccc2n1C=O.NO>>Cc1noc(C)c1-c1c(-c2ccc(O)cc2)c2ccccc2n1C=NO -US20130303532A1,9,O=C(NC1CC1)c1ccc(-c2cnc3c(NCCCO)nc(Br)cn23)cc1>>O=C(NC1CC1)c1ccc(-c2cnc3c(NCCCO)nccn23)cc1 -US06518265B1,9,[N-]=[N+]=NCC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1>>NCC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_0_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_0_log.txt deleted file mode 100644 index 6a6c1ed..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_0_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-17 12:56:57,412 - Start process.... -2024-06-17 12:56:57,412 - Loading database.... -2024-06-17 12:56:57,436 - Processing from 0 to 500 -2024-06-17 13:01:44,443 - Processing from 500 to 1000 -2024-06-17 13:06:45,838 - Processing from 1000 to 1500 -2024-06-17 13:11:39,635 - Processing from 1500 to 2000 -2024-06-17 13:16:39,289 - Processing from 2000 to 2500 -2024-06-17 13:21:35,744 - Processing from 2500 to 3000 -2024-06-17 13:26:47,056 - Processing from 3000 to 3500 -2024-06-17 13:31:57,697 - Processing from 3500 to 4000 -2024-06-17 13:38:16,192 - Processing from 4000 to 4500 -2024-06-17 13:43:51,909 - Processing from 4500 to 5000 -2024-06-17 13:49:13,805 - Processing from 5000 to 5500 -2024-06-17 13:49:16,509 - Forward Prediction Validation -2024-06-17 13:49:23,490 - Top 1 accuracy for Random: 6.24 -2024-06-17 13:49:36,039 - Top 3 accuracy for Random: 13.97 -2024-06-17 13:49:55,430 - Top 5 accuracy for Random: 19.67 -2024-06-17 13:50:27,806 - Top 10 accuracy for Random: 32.99 -2024-06-17 13:53:19,196 - Top 1 accuracy for ECFP6: 8.98 -2024-06-17 13:56:13,654 - Top 3 accuracy for ECFP6: 24.45 -2024-06-17 13:59:05,822 - Top 5 accuracy for ECFP6: 37.09 -2024-06-17 14:02:10,418 - Top 10 accuracy for ECFP6: 55.62 -2024-06-17 14:11:30,105 - Top 1 accuracy for MACCS: 8.72 -2024-06-17 14:21:43,266 - Top 3 accuracy for MACCS: 17.97 -2024-06-17 14:31:43,650 - Top 5 accuracy for MACCS: 25.91 -2024-06-17 14:41:58,105 - Top 10 accuracy for MACCS: 42.32 -2024-06-17 14:51:02,655 - Top 1 accuracy for RDK7: 8.98 -2024-06-17 14:59:27,918 - Top 3 accuracy for RDK7: 18.93 -2024-06-17 15:07:52,456 - Top 5 accuracy for RDK7: 26.87 -2024-06-17 15:16:03,545 - Top 10 accuracy for RDK7: 43.02 -2024-06-17 15:16:03,550 - Backward Prediction Validation -2024-06-17 15:16:09,018 - Top 1 accuracy for Random: 5.68 -2024-06-17 15:16:21,113 - Top 3 accuracy for Random: 15.49 -2024-06-17 15:16:37,333 - Top 5 accuracy for Random: 23.95 -2024-06-17 15:17:03,044 - Top 10 accuracy for Random: 41.7 -2024-06-17 15:18:37,468 - Top 1 accuracy for ECFP6: 3.52 -2024-06-17 15:20:09,047 - Top 3 accuracy for ECFP6: 13.83 -2024-06-17 15:21:42,659 - Top 5 accuracy for ECFP6: 25.41 -2024-06-17 15:23:30,705 - Top 10 accuracy for ECFP6: 49.88 -2024-06-17 15:28:16,731 - Top 1 accuracy for MACCS: 6.66 -2024-06-17 15:35:03,333 - Top 3 accuracy for MACCS: 18.37 -2024-06-17 15:40:08,426 - Top 5 accuracy for MACCS: 29.11 -2024-06-17 15:45:27,657 - Top 10 accuracy for MACCS: 49.28 -2024-06-17 15:50:22,615 - Top 1 accuracy for RDK7: 3.52 -2024-06-17 15:55:09,499 - Top 3 accuracy for RDK7: 12.14 -2024-06-17 15:59:43,918 - Top 5 accuracy for RDK7: 20.15 -2024-06-17 16:04:45,276 - Top 10 accuracy for RDK7: 39.9 -2024-06-17 16:04:45,283 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 8.98 55.62 24.45 37.09 -MACCS 8.72 42.32 17.97 25.91 -RDK7 8.98 43.02 18.93 26.87 -Random 6.24 32.99 13.97 19.67 -2024-06-17 16:04:45,285 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 3.52 49.88 13.83 25.41 -MACCS 6.66 49.28 18.37 29.11 -RDK7 3.52 39.90 12.14 20.15 -Random 5.68 41.70 15.49 23.95 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_1_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_1_log.txt deleted file mode 100644 index 95a3949..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_1_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-17 12:57:18,877 - Start process.... -2024-06-17 12:57:18,877 - Loading database.... -2024-06-17 12:57:18,907 - Processing from 0 to 500 -2024-06-17 13:03:28,303 - Processing from 500 to 1000 -2024-06-17 13:09:37,383 - Processing from 1000 to 1500 -2024-06-17 13:15:51,918 - Processing from 1500 to 2000 -2024-06-17 13:22:04,030 - Processing from 2000 to 2500 -2024-06-17 13:28:23,501 - Processing from 2500 to 3000 -2024-06-17 13:35:02,657 - Processing from 3000 to 3500 -2024-06-17 13:42:37,512 - Processing from 3500 to 4000 -2024-06-17 13:48:41,043 - Processing from 4000 to 4500 -2024-06-17 13:54:55,417 - Processing from 4500 to 5000 -2024-06-17 14:01:30,721 - Processing from 5000 to 5500 -2024-06-17 14:01:33,246 - Forward Prediction Validation -2024-06-17 14:01:40,162 - Top 1 accuracy for Random: 21.39 -2024-06-17 14:01:52,110 - Top 3 accuracy for Random: 40.0 -2024-06-17 14:02:06,311 - Top 5 accuracy for Random: 52.18 -2024-06-17 14:02:27,499 - Top 10 accuracy for Random: 64.13 -2024-06-17 14:03:15,936 - Top 1 accuracy for ECFP6: 40.06 -2024-06-17 14:04:13,542 - Top 3 accuracy for ECFP6: 63.15 -2024-06-17 14:05:14,666 - Top 5 accuracy for ECFP6: 72.17 -2024-06-17 14:06:23,005 - Top 10 accuracy for ECFP6: 76.83 -2024-06-17 14:09:14,407 - Top 1 accuracy for MACCS: 30.35 -2024-06-17 14:11:54,242 - Top 3 accuracy for MACCS: 52.94 -2024-06-17 14:14:50,303 - Top 5 accuracy for MACCS: 63.71 -2024-06-17 14:18:10,459 - Top 10 accuracy for MACCS: 73.25 -2024-06-17 14:21:20,734 - Top 1 accuracy for RDK7: 30.99 -2024-06-17 14:24:47,473 - Top 3 accuracy for RDK7: 56.22 -2024-06-17 14:27:42,559 - Top 5 accuracy for RDK7: 67.33 -2024-06-17 14:31:11,558 - Top 10 accuracy for RDK7: 75.57 -2024-06-17 14:31:11,562 - Backward Prediction Validation -2024-06-17 14:31:19,765 - Top 1 accuracy for Random: 20.95 -2024-06-17 14:31:32,061 - Top 3 accuracy for Random: 45.32 -2024-06-17 14:31:49,303 - Top 5 accuracy for Random: 61.6 -2024-06-17 14:32:14,137 - Top 10 accuracy for Random: 73.99 -2024-06-17 14:32:44,777 - Top 1 accuracy for ECFP6: 23.45 -2024-06-17 14:33:18,777 - Top 3 accuracy for ECFP6: 53.1 -2024-06-17 14:34:03,426 - Top 5 accuracy for ECFP6: 67.97 -2024-06-17 14:34:46,111 - Top 10 accuracy for ECFP6: 76.53 -2024-06-17 14:36:11,245 - Top 1 accuracy for MACCS: 21.65 -2024-06-17 14:37:49,892 - Top 3 accuracy for MACCS: 50.58 -2024-06-17 14:39:23,741 - Top 5 accuracy for MACCS: 64.35 -2024-06-17 14:41:07,167 - Top 10 accuracy for MACCS: 74.51 -2024-06-17 14:42:25,463 - Top 1 accuracy for RDK7: 19.35 -2024-06-17 14:43:50,326 - Top 3 accuracy for RDK7: 42.52 -2024-06-17 14:45:15,573 - Top 5 accuracy for RDK7: 59.94 -2024-06-17 14:46:44,279 - Top 10 accuracy for RDK7: 75.25 -2024-06-17 14:46:44,286 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 40.06 76.83 63.15 72.17 -MACCS 30.35 73.25 52.94 63.71 -RDK7 30.99 75.57 56.22 67.33 -Random 21.39 64.13 40.00 52.18 -2024-06-17 14:46:44,287 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 23.45 76.53 53.10 67.97 -MACCS 21.65 74.51 50.58 64.35 -RDK7 19.35 75.25 42.52 59.94 -Random 20.95 73.99 45.32 61.60 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_2_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_2_log.txt deleted file mode 100644 index c68637f..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_2_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-17 12:57:35,758 - Start process.... -2024-06-17 12:57:35,758 - Loading database.... -2024-06-17 12:57:35,791 - Processing from 0 to 500 -2024-06-17 13:07:09,846 - Processing from 500 to 1000 -2024-06-17 13:17:01,879 - Processing from 1000 to 1500 -2024-06-17 13:26:51,138 - Processing from 1500 to 2000 -2024-06-17 13:37:32,847 - Processing from 2000 to 2500 -2024-06-17 13:47:38,492 - Processing from 2500 to 3000 -2024-06-17 13:57:11,798 - Processing from 3000 to 3500 -2024-06-17 14:06:57,533 - Processing from 3500 to 4000 -2024-06-17 14:16:03,537 - Processing from 4000 to 4500 -2024-06-17 14:25:41,169 - Processing from 4500 to 5000 -2024-06-17 14:35:37,759 - Processing from 5000 to 5500 -2024-06-17 14:35:41,100 - Forward Prediction Validation -2024-06-17 14:35:48,875 - Top 1 accuracy for Random: 39.42 -2024-06-17 14:36:01,226 - Top 3 accuracy for Random: 62.63 -2024-06-17 14:36:15,157 - Top 5 accuracy for Random: 69.91 -2024-06-17 14:36:30,342 - Top 10 accuracy for Random: 73.51 -2024-06-17 14:36:47,339 - Top 1 accuracy for ECFP6: 52.26 -2024-06-17 14:37:09,891 - Top 3 accuracy for ECFP6: 69.21 -2024-06-17 14:37:35,170 - Top 5 accuracy for ECFP6: 72.95 -2024-06-17 14:38:02,486 - Top 10 accuracy for ECFP6: 74.51 -2024-06-17 14:38:43,506 - Top 1 accuracy for MACCS: 45.06 -2024-06-17 14:39:34,676 - Top 3 accuracy for MACCS: 64.53 -2024-06-17 14:40:22,354 - Top 5 accuracy for MACCS: 70.73 -2024-06-17 14:41:17,422 - Top 10 accuracy for MACCS: 74.31 -2024-06-17 14:41:58,021 - Top 1 accuracy for RDK7: 44.88 -2024-06-17 14:42:44,838 - Top 3 accuracy for RDK7: 65.95 -2024-06-17 14:43:29,536 - Top 5 accuracy for RDK7: 71.93 -2024-06-17 14:44:16,947 - Top 10 accuracy for RDK7: 74.37 -2024-06-17 14:44:16,951 - Backward Prediction Validation -2024-06-17 14:44:23,613 - Top 1 accuracy for Random: 26.89 -2024-06-17 14:44:33,790 - Top 3 accuracy for Random: 55.3 -2024-06-17 14:44:48,153 - Top 5 accuracy for Random: 66.93 -2024-06-17 14:45:04,362 - Top 10 accuracy for Random: 74.17 -2024-06-17 14:45:22,441 - Top 1 accuracy for ECFP6: 32.23 -2024-06-17 14:45:44,894 - Top 3 accuracy for ECFP6: 62.22 -2024-06-17 14:46:11,571 - Top 5 accuracy for ECFP6: 71.73 -2024-06-17 14:46:38,566 - Top 10 accuracy for ECFP6: 74.65 -2024-06-17 14:47:21,221 - Top 1 accuracy for MACCS: 28.49 -2024-06-17 14:48:06,875 - Top 3 accuracy for MACCS: 58.9 -2024-06-17 14:49:01,220 - Top 5 accuracy for MACCS: 69.45 -2024-06-17 14:50:00,109 - Top 10 accuracy for MACCS: 74.47 -2024-06-17 14:50:46,549 - Top 1 accuracy for RDK7: 26.31 -2024-06-17 14:51:37,991 - Top 3 accuracy for RDK7: 53.68 -2024-06-17 14:52:32,275 - Top 5 accuracy for RDK7: 67.11 -2024-06-17 14:53:29,186 - Top 10 accuracy for RDK7: 74.49 -2024-06-17 14:53:29,204 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 52.26 74.51 69.21 72.95 -MACCS 45.06 74.31 64.53 70.73 -RDK7 44.88 74.37 65.95 71.93 -Random 39.42 73.51 62.63 69.91 -2024-06-17 14:53:29,205 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 32.23 74.65 62.22 71.73 -MACCS 28.49 74.47 58.90 69.45 -RDK7 26.31 74.49 53.68 67.11 -Random 26.89 74.17 55.30 66.93 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_3_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_3_log.txt deleted file mode 100644 index 64324ce..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/hier_rule_3_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-17 10:33:27,257 - Start process.... -2024-06-17 10:33:27,257 - Loading database.... -2024-06-17 10:33:27,282 - Processing from 0 to 500 -2024-06-17 10:43:21,299 - Processing from 500 to 1000 -2024-06-17 10:53:49,707 - Processing from 1000 to 1500 -2024-06-17 11:04:04,591 - Processing from 1500 to 2000 -2024-06-17 11:14:20,403 - Processing from 2000 to 2500 -2024-06-17 11:24:52,072 - Processing from 2500 to 3000 -2024-06-17 11:35:04,302 - Processing from 3000 to 3500 -2024-06-17 11:47:10,525 - Processing from 3500 to 4000 -2024-06-17 11:57:59,978 - Processing from 4000 to 4500 -2024-06-17 12:08:12,107 - Processing from 4500 to 5000 -2024-06-17 12:18:18,712 - Processing from 5000 to 5500 -2024-06-17 12:18:21,837 - Forward Prediction Validation -2024-06-17 12:18:26,326 - Top 1 accuracy for Random: 41.22 -2024-06-17 12:18:32,584 - Top 3 accuracy for Random: 59.72 -2024-06-17 12:18:39,896 - Top 5 accuracy for Random: 64.17 -2024-06-17 12:18:48,458 - Top 10 accuracy for Random: 65.99 -2024-06-17 12:18:58,052 - Top 1 accuracy for ECFP6: 49.94 -2024-06-17 12:19:09,302 - Top 3 accuracy for ECFP6: 63.43 -2024-06-17 12:19:21,447 - Top 5 accuracy for ECFP6: 65.39 -2024-06-17 12:19:35,278 - Top 10 accuracy for ECFP6: 66.15 -2024-06-17 12:19:56,637 - Top 1 accuracy for MACCS: 44.56 -2024-06-17 12:20:19,324 - Top 3 accuracy for MACCS: 60.12 -2024-06-17 12:20:44,253 - Top 5 accuracy for MACCS: 64.15 -2024-06-17 12:21:09,586 - Top 10 accuracy for MACCS: 66.13 -2024-06-17 12:21:30,486 - Top 1 accuracy for RDK7: 44.62 -2024-06-17 12:21:52,956 - Top 3 accuracy for RDK7: 61.74 -2024-06-17 12:22:17,626 - Top 5 accuracy for RDK7: 64.87 -2024-06-17 12:22:47,928 - Top 10 accuracy for RDK7: 66.09 -2024-06-17 12:22:47,934 - Backward Prediction Validation -2024-06-17 12:22:53,206 - Top 1 accuracy for Random: 29.85 -2024-06-17 12:23:02,138 - Top 3 accuracy for Random: 55.08 -2024-06-17 12:23:11,440 - Top 5 accuracy for Random: 62.91 -2024-06-17 12:23:22,952 - Top 10 accuracy for Random: 66.15 -2024-06-17 12:23:40,823 - Top 1 accuracy for ECFP6: 36.99 -2024-06-17 12:24:04,854 - Top 3 accuracy for ECFP6: 60.42 -2024-06-17 12:24:24,628 - Top 5 accuracy for ECFP6: 65.25 -2024-06-17 12:24:43,427 - Top 10 accuracy for ECFP6: 66.31 -2024-06-17 12:25:14,414 - Top 1 accuracy for MACCS: 31.27 -2024-06-17 12:25:49,109 - Top 3 accuracy for MACCS: 57.2 -2024-06-17 12:26:24,139 - Top 5 accuracy for MACCS: 64.41 -2024-06-17 12:27:00,623 - Top 10 accuracy for MACCS: 66.23 -2024-06-17 12:27:29,802 - Top 1 accuracy for RDK7: 29.99 -2024-06-17 12:28:02,293 - Top 3 accuracy for RDK7: 54.56 -2024-06-17 12:28:35,888 - Top 5 accuracy for RDK7: 63.51 -2024-06-17 12:29:14,384 - Top 10 accuracy for RDK7: 66.25 -2024-06-17 12:29:14,392 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 49.94 66.15 63.43 65.39 -MACCS 44.56 66.13 60.12 64.15 -RDK7 44.62 66.09 61.74 64.87 -Random 41.22 65.99 59.72 64.17 -2024-06-17 12:29:14,393 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 36.99 66.31 60.42 65.25 -MACCS 31.27 66.23 57.20 64.41 -RDK7 29.99 66.25 54.56 63.51 -Random 29.85 66.15 55.08 62.91 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r0_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r0_log.txt deleted file mode 100644 index 8667e66..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r0_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 13:58:22,480 - Start process.... -2024-06-14 13:58:22,481 - Loading database.... -2024-06-14 13:58:22,504 - Processing from 0 to 500 -2024-06-14 14:02:05,557 - Processing from 500 to 1000 -2024-06-14 14:05:37,392 - Processing from 1000 to 1500 -2024-06-14 14:09:12,475 - Processing from 1500 to 2000 -2024-06-14 14:12:38,052 - Processing from 2000 to 2500 -2024-06-14 14:16:03,474 - Processing from 2500 to 3000 -2024-06-14 14:19:47,144 - Processing from 3000 to 3500 -2024-06-14 14:23:30,757 - Processing from 3500 to 4000 -2024-06-14 14:26:48,426 - Processing from 4000 to 4500 -2024-06-14 14:30:21,894 - Processing from 4500 to 5000 -2024-06-14 14:34:05,760 - Processing from 5000 to 5500 -2024-06-14 14:34:07,526 - Forward Prediction Validation -2024-06-14 14:34:13,893 - Top 1 accuracy for Random: 6.16 -2024-06-14 14:34:25,581 - Top 3 accuracy for Random: 14.03 -2024-06-14 14:34:43,026 - Top 5 accuracy for Random: 19.69 -2024-06-14 14:35:14,949 - Top 10 accuracy for Random: 32.49 -2024-06-14 14:37:32,788 - Top 1 accuracy for ECFP6: 8.86 -2024-06-14 14:39:52,709 - Top 3 accuracy for ECFP6: 24.53 -2024-06-14 14:42:15,409 - Top 5 accuracy for ECFP6: 37.19 -2024-06-14 14:44:52,066 - Top 10 accuracy for ECFP6: 55.74 -2024-06-14 14:53:29,171 - Top 1 accuracy for MACCS: 8.74 -2024-06-14 15:02:19,918 - Top 3 accuracy for MACCS: 17.75 -2024-06-14 15:10:05,193 - Top 5 accuracy for MACCS: 25.99 -2024-06-14 15:18:19,804 - Top 10 accuracy for MACCS: 42.54 -2024-06-14 15:26:33,699 - Top 1 accuracy for RDK7: 8.98 -2024-06-14 15:34:22,347 - Top 3 accuracy for RDK7: 18.93 -2024-06-14 15:42:20,694 - Top 5 accuracy for RDK7: 26.83 -2024-06-14 15:50:27,682 - Top 10 accuracy for RDK7: 43.02 -2024-06-14 15:50:27,688 - Backward Prediction Validation -2024-06-14 15:50:33,321 - Top 1 accuracy for Random: 5.16 -2024-06-14 15:50:44,178 - Top 3 accuracy for Random: 15.79 -2024-06-14 15:51:00,401 - Top 5 accuracy for Random: 24.43 -2024-06-14 15:51:26,772 - Top 10 accuracy for Random: 41.6 -2024-06-14 15:52:48,730 - Top 1 accuracy for ECFP6: 3.54 -2024-06-14 15:54:15,688 - Top 3 accuracy for ECFP6: 13.95 -2024-06-14 15:55:47,899 - Top 5 accuracy for ECFP6: 25.31 -2024-06-14 15:57:59,796 - Top 10 accuracy for ECFP6: 49.82 -2024-06-14 16:04:13,225 - Top 1 accuracy for MACCS: 6.62 -2024-06-14 16:10:49,040 - Top 3 accuracy for MACCS: 18.39 -2024-06-14 16:17:41,621 - Top 5 accuracy for MACCS: 28.73 -2024-06-14 16:24:46,458 - Top 10 accuracy for MACCS: 49.14 -2024-06-14 16:31:11,582 - Top 1 accuracy for RDK7: 3.56 -2024-06-14 16:37:57,043 - Top 3 accuracy for RDK7: 12.12 -2024-06-14 16:45:01,887 - Top 5 accuracy for RDK7: 20.11 -2024-06-14 16:52:02,428 - Top 10 accuracy for RDK7: 39.9 -2024-06-14 16:52:02,434 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 8.86 55.74 24.53 37.19 -MACCS 8.74 42.54 17.75 25.99 -RDK7 8.98 43.02 18.93 26.83 -Random 6.16 32.49 14.03 19.69 -2024-06-14 16:52:02,436 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 3.54 49.82 13.95 25.31 -MACCS 6.62 49.14 18.39 28.73 -RDK7 3.56 39.90 12.12 20.11 -Random 5.16 41.60 15.79 24.43 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r1_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r1_log.txt deleted file mode 100644 index b21918f..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r1_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 13:59:51,371 - Start process.... -2024-06-14 13:59:51,371 - Loading database.... -2024-06-14 13:59:51,398 - Processing from 0 to 500 -2024-06-14 14:20:08,028 - Processing from 500 to 1000 -2024-06-14 14:40:02,293 - Processing from 1000 to 1500 -2024-06-14 15:00:26,106 - Processing from 1500 to 2000 -2024-06-14 15:18:28,295 - Processing from 2000 to 2500 -2024-06-14 15:35:51,468 - Processing from 2500 to 3000 -2024-06-14 15:52:53,865 - Processing from 3000 to 3500 -2024-06-14 16:22:24,942 - Processing from 3500 to 4000 -2024-06-14 16:54:20,943 - Processing from 4000 to 4500 -2024-06-14 17:25:48,388 - Processing from 4500 to 5000 -2024-06-14 18:01:20,246 - Processing from 5000 to 5500 -2024-06-14 18:01:28,497 - Forward Prediction Validation -2024-06-14 18:01:34,756 - Top 1 accuracy for Random: 21.37 -2024-06-14 18:01:51,696 - Top 3 accuracy for Random: 41.28 -2024-06-14 18:02:11,434 - Top 5 accuracy for Random: 52.02 -2024-06-14 18:02:41,344 - Top 10 accuracy for Random: 64.23 -2024-06-14 18:03:45,835 - Top 1 accuracy for ECFP6: 39.74 -2024-06-14 18:04:57,922 - Top 3 accuracy for ECFP6: 63.23 -2024-06-14 18:06:15,009 - Top 5 accuracy for ECFP6: 72.09 -2024-06-14 18:07:45,676 - Top 10 accuracy for ECFP6: 76.87 -2024-06-14 18:11:20,219 - Top 1 accuracy for MACCS: 30.09 -2024-06-14 18:14:53,524 - Top 3 accuracy for MACCS: 53.26 -2024-06-14 18:18:38,375 - Top 5 accuracy for MACCS: 63.53 -2024-06-14 18:22:30,389 - Top 10 accuracy for MACCS: 73.33 -2024-06-14 18:26:20,017 - Top 1 accuracy for RDK7: 31.03 -2024-06-14 18:30:07,463 - Top 3 accuracy for RDK7: 56.26 -2024-06-14 18:34:04,494 - Top 5 accuracy for RDK7: 67.39 -2024-06-14 18:38:10,221 - Top 10 accuracy for RDK7: 75.63 -2024-06-14 18:38:10,228 - Backward Prediction Validation -2024-06-14 18:38:18,601 - Top 1 accuracy for Random: 20.73 -2024-06-14 18:38:33,691 - Top 3 accuracy for Random: 46.32 -2024-06-14 18:38:54,664 - Top 5 accuracy for Random: 60.94 -2024-06-14 18:39:24,716 - Top 10 accuracy for Random: 74.17 -2024-06-14 18:40:01,978 - Top 1 accuracy for ECFP6: 23.09 -2024-06-14 18:40:45,274 - Top 3 accuracy for ECFP6: 53.14 -2024-06-14 18:41:36,780 - Top 5 accuracy for ECFP6: 67.89 -2024-06-14 18:42:34,193 - Top 10 accuracy for ECFP6: 76.57 -2024-06-14 18:44:25,560 - Top 1 accuracy for MACCS: 21.31 -2024-06-14 18:46:19,958 - Top 3 accuracy for MACCS: 50.74 -2024-06-14 18:48:23,697 - Top 5 accuracy for MACCS: 64.39 -2024-06-14 18:50:28,416 - Top 10 accuracy for MACCS: 74.51 -2024-06-14 18:52:11,244 - Top 1 accuracy for RDK7: 19.37 -2024-06-14 18:53:57,076 - Top 3 accuracy for RDK7: 42.56 -2024-06-14 18:55:48,565 - Top 5 accuracy for RDK7: 59.98 -2024-06-14 18:57:46,346 - Top 10 accuracy for RDK7: 75.29 -2024-06-14 18:57:46,354 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 39.74 76.87 63.23 72.09 -MACCS 30.09 73.33 53.26 63.53 -RDK7 31.03 75.63 56.26 67.39 -Random 21.37 64.23 41.28 52.02 -2024-06-14 18:57:46,356 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 23.09 76.57 53.14 67.89 -MACCS 21.31 74.51 50.74 64.39 -RDK7 19.37 75.29 42.56 59.98 -Random 20.73 74.17 46.32 60.94 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r2_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r2_log.txt deleted file mode 100644 index c4d950b..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r2_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 17:33:15,800 - Start process.... -2024-06-14 17:33:15,800 - Loading database.... -2024-06-14 17:33:15,833 - Processing from 0 to 500 -2024-06-14 21:41:00,781 - Processing from 500 to 1000 -2024-06-15 01:34:13,673 - Processing from 1000 to 1500 -2024-06-15 05:26:17,043 - Processing from 1500 to 2000 -2024-06-15 09:30:43,066 - Processing from 2000 to 2500 -2024-06-15 13:15:42,585 - Processing from 2500 to 3000 -2024-06-15 16:56:51,354 - Processing from 3000 to 3500 -2024-06-15 20:39:29,299 - Processing from 3500 to 4000 -2024-06-16 00:19:06,979 - Processing from 4000 to 4500 -2024-06-16 04:00:40,108 - Processing from 4500 to 5000 -2024-06-16 07:50:24,324 - Processing from 5000 to 5500 -2024-06-16 07:51:12,727 - Forward Prediction Validation -2024-06-16 07:51:18,414 - Top 1 accuracy for Random: 39.48 -2024-06-16 07:51:27,043 - Top 3 accuracy for Random: 63.19 -2024-06-16 07:51:37,842 - Top 5 accuracy for Random: 69.57 -2024-06-16 07:51:52,322 - Top 10 accuracy for Random: 73.71 -2024-06-16 07:52:07,375 - Top 1 accuracy for ECFP6: 52.12 -2024-06-16 07:52:25,497 - Top 3 accuracy for ECFP6: 69.11 -2024-06-16 07:52:45,363 - Top 5 accuracy for ECFP6: 73.01 -2024-06-16 07:53:09,075 - Top 10 accuracy for ECFP6: 74.55 -2024-06-16 07:53:47,815 - Top 1 accuracy for MACCS: 44.82 -2024-06-16 07:54:31,024 - Top 3 accuracy for MACCS: 64.45 -2024-06-16 07:55:13,102 - Top 5 accuracy for MACCS: 70.75 -2024-06-16 07:56:00,687 - Top 10 accuracy for MACCS: 74.33 -2024-06-16 07:56:38,628 - Top 1 accuracy for RDK7: 44.86 -2024-06-16 07:57:19,500 - Top 3 accuracy for RDK7: 65.97 -2024-06-16 07:58:07,088 - Top 5 accuracy for RDK7: 71.95 -2024-06-16 07:58:54,348 - Top 10 accuracy for RDK7: 74.39 -2024-06-16 07:58:54,357 - Backward Prediction Validation -2024-06-16 07:59:00,015 - Top 1 accuracy for Random: 26.83 -2024-06-16 07:59:10,663 - Top 3 accuracy for Random: 54.84 -2024-06-16 07:59:25,111 - Top 5 accuracy for Random: 67.75 -2024-06-16 07:59:41,897 - Top 10 accuracy for Random: 74.13 -2024-06-16 08:00:01,922 - Top 1 accuracy for ECFP6: 32.23 -2024-06-16 08:00:28,113 - Top 3 accuracy for ECFP6: 62.42 -2024-06-16 08:00:54,124 - Top 5 accuracy for ECFP6: 71.69 -2024-06-16 08:01:25,112 - Top 10 accuracy for ECFP6: 74.65 -2024-06-16 08:02:14,861 - Top 1 accuracy for MACCS: 28.21 -2024-06-16 08:03:09,663 - Top 3 accuracy for MACCS: 58.98 -2024-06-16 08:04:06,114 - Top 5 accuracy for MACCS: 69.59 -2024-06-16 08:05:04,553 - Top 10 accuracy for MACCS: 74.51 -2024-06-16 08:05:53,656 - Top 1 accuracy for RDK7: 26.31 -2024-06-16 08:06:45,052 - Top 3 accuracy for RDK7: 53.7 -2024-06-16 08:07:40,846 - Top 5 accuracy for RDK7: 67.13 -2024-06-16 08:08:42,777 - Top 10 accuracy for RDK7: 74.53 -2024-06-16 08:08:42,786 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 52.12 74.55 69.11 73.01 -MACCS 44.82 74.33 64.45 70.75 -RDK7 44.86 74.39 65.97 71.95 -Random 39.48 73.71 63.19 69.57 -2024-06-16 08:08:42,787 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 32.23 74.65 62.42 71.69 -MACCS 28.21 74.51 58.98 69.59 -RDK7 26.31 74.53 53.70 67.13 -Random 26.83 74.13 54.84 67.75 diff --git a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r3_log.txt b/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r3_log.txt deleted file mode 100644 index 7c22a7e..0000000 --- a/Data/DPO/USPTO_50K/Good_hydrogen/Log/rules_r3_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 17:33:31,257 - Start process.... -2024-06-14 17:33:31,258 - Loading database.... -2024-06-14 17:33:31,294 - Processing from 0 to 500 -2024-06-15 03:16:52,790 - Processing from 500 to 1000 -2024-06-15 13:02:32,240 - Processing from 1000 to 1500 -2024-06-15 22:03:50,388 - Processing from 1500 to 2000 -2024-06-16 07:13:58,283 - Processing from 2000 to 2500 -2024-06-16 15:49:51,721 - Processing from 2500 to 3000 -2024-06-16 23:44:02,322 - Processing from 3000 to 3500 -2024-06-17 07:16:23,884 - Processing from 3500 to 4000 -2024-06-17 15:34:33,044 - Processing from 4000 to 4500 -2024-06-17 23:24:18,979 - Processing from 4500 to 5000 -2024-06-18 07:00:52,171 - Processing from 5000 to 5500 -2024-06-18 07:02:32,457 - Forward Prediction Validation -2024-06-18 07:02:37,852 - Top 1 accuracy for Random: 40.96 -2024-06-18 07:02:45,563 - Top 3 accuracy for Random: 60.02 -2024-06-18 07:02:55,673 - Top 5 accuracy for Random: 64.19 -2024-06-18 07:03:04,921 - Top 10 accuracy for Random: 66.15 -2024-06-18 07:03:15,301 - Top 1 accuracy for ECFP6: 49.86 -2024-06-18 07:03:27,471 - Top 3 accuracy for ECFP6: 63.47 -2024-06-18 07:03:39,549 - Top 5 accuracy for ECFP6: 65.37 -2024-06-18 07:03:51,499 - Top 10 accuracy for ECFP6: 66.15 -2024-06-18 07:04:12,025 - Top 1 accuracy for MACCS: 44.82 -2024-06-18 07:04:34,011 - Top 3 accuracy for MACCS: 60.12 -2024-06-18 07:04:57,152 - Top 5 accuracy for MACCS: 64.21 -2024-06-18 07:05:22,224 - Top 10 accuracy for MACCS: 66.11 -2024-06-18 07:05:43,181 - Top 1 accuracy for RDK7: 44.62 -2024-06-18 07:06:11,506 - Top 3 accuracy for RDK7: 61.74 -2024-06-18 07:06:38,644 - Top 5 accuracy for RDK7: 64.87 -2024-06-18 07:07:01,696 - Top 10 accuracy for RDK7: 66.09 -2024-06-18 07:07:01,702 - Backward Prediction Validation -2024-06-18 07:07:06,326 - Top 1 accuracy for Random: 29.89 -2024-06-18 07:07:13,794 - Top 3 accuracy for Random: 54.06 -2024-06-18 07:07:23,037 - Top 5 accuracy for Random: 62.71 -2024-06-18 07:07:33,238 - Top 10 accuracy for Random: 66.17 -2024-06-18 07:07:44,684 - Top 1 accuracy for ECFP6: 37.23 -2024-06-18 07:07:59,261 - Top 3 accuracy for ECFP6: 60.52 -2024-06-18 07:08:16,950 - Top 5 accuracy for ECFP6: 65.29 -2024-06-18 07:08:34,737 - Top 10 accuracy for ECFP6: 66.31 -2024-06-18 07:09:04,960 - Top 1 accuracy for MACCS: 31.35 -2024-06-18 07:09:37,039 - Top 3 accuracy for MACCS: 57.12 -2024-06-18 07:10:13,078 - Top 5 accuracy for MACCS: 64.43 -2024-06-18 07:10:50,069 - Top 10 accuracy for MACCS: 66.25 -2024-06-18 07:11:19,218 - Top 1 accuracy for RDK7: 30.01 -2024-06-18 07:11:53,322 - Top 3 accuracy for RDK7: 54.56 -2024-06-18 07:12:33,419 - Top 5 accuracy for RDK7: 63.49 -2024-06-18 07:13:14,262 - Top 10 accuracy for RDK7: 66.25 -2024-06-18 07:13:14,271 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 49.86 66.15 63.47 65.37 -MACCS 44.82 66.11 60.12 64.21 -RDK7 44.62 66.09 61.74 64.87 -Random 40.96 66.15 60.02 64.19 -2024-06-18 07:13:14,272 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 37.23 66.31 60.52 65.29 -MACCS 31.35 66.25 57.12 64.43 -RDK7 30.01 66.25 54.56 63.49 -Random 29.89 66.17 54.06 62.71 diff --git a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r0_log.txt b/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r0_log.txt deleted file mode 100644 index 3fc808c..0000000 --- a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r0_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 13:58:02,441 - Start process.... -2024-06-14 13:58:02,442 - Loading database.... -2024-06-14 13:58:02,464 - Processing from 0 to 500 -2024-06-14 14:04:12,807 - Processing from 500 to 1000 -2024-06-14 14:10:35,854 - Processing from 1000 to 1500 -2024-06-14 14:16:43,209 - Processing from 1500 to 2000 -2024-06-14 14:23:10,094 - Processing from 2000 to 2500 -2024-06-14 14:29:10,170 - Processing from 2500 to 3000 -2024-06-14 14:35:27,573 - Processing from 3000 to 3500 -2024-06-14 14:41:06,952 - Processing from 3500 to 4000 -2024-06-14 14:46:44,870 - Processing from 4000 to 4500 -2024-06-14 14:53:14,489 - Processing from 4500 to 5000 -2024-06-14 15:00:24,026 - Processing from 5000 to 5500 -2024-06-14 15:00:27,437 - Forward Prediction Validation -2024-06-14 15:00:33,947 - Top 1 accuracy for Random: 5.92 -2024-06-14 15:00:46,373 - Top 3 accuracy for Random: 13.13 -2024-06-14 15:01:02,643 - Top 5 accuracy for Random: 19.75 -2024-06-14 15:01:30,661 - Top 10 accuracy for Random: 32.27 -2024-06-14 15:03:45,968 - Top 1 accuracy for ECFP6: 8.4 -2024-06-14 15:06:11,152 - Top 3 accuracy for ECFP6: 22.85 -2024-06-14 15:08:49,948 - Top 5 accuracy for ECFP6: 35.67 -2024-06-14 15:11:31,001 - Top 10 accuracy for ECFP6: 54.78 -2024-06-14 15:19:47,052 - Top 1 accuracy for MACCS: 8.9 -2024-06-14 15:27:53,216 - Top 3 accuracy for MACCS: 17.75 -2024-06-14 15:35:33,374 - Top 5 accuracy for MACCS: 25.87 -2024-06-14 15:43:29,413 - Top 10 accuracy for MACCS: 41.66 -2024-06-14 15:51:41,422 - Top 1 accuracy for RDK7: 8.98 -2024-06-14 16:00:53,771 - Top 3 accuracy for RDK7: 18.99 -2024-06-14 16:12:19,411 - Top 5 accuracy for RDK7: 26.83 -2024-06-14 16:24:01,579 - Top 10 accuracy for RDK7: 42.84 -2024-06-14 16:24:01,585 - Backward Prediction Validation -2024-06-14 16:24:08,893 - Top 1 accuracy for Random: 5.16 -2024-06-14 16:24:23,752 - Top 3 accuracy for Random: 14.45 -2024-06-14 16:24:45,168 - Top 5 accuracy for Random: 22.87 -2024-06-14 16:25:23,128 - Top 10 accuracy for Random: 39.66 -2024-06-14 16:27:31,835 - Top 1 accuracy for ECFP6: 3.54 -2024-06-14 16:29:44,767 - Top 3 accuracy for ECFP6: 14.19 -2024-06-14 16:32:03,642 - Top 5 accuracy for ECFP6: 25.87 -2024-06-14 16:34:40,121 - Top 10 accuracy for ECFP6: 50.22 -2024-06-14 16:41:54,562 - Top 1 accuracy for MACCS: 6.74 -2024-06-14 16:49:14,614 - Top 3 accuracy for MACCS: 18.53 -2024-06-14 16:55:28,096 - Top 5 accuracy for MACCS: 29.11 -2024-06-14 17:02:12,090 - Top 10 accuracy for MACCS: 49.08 -2024-06-14 17:08:16,407 - Top 1 accuracy for RDK7: 3.82 -2024-06-14 17:14:19,646 - Top 3 accuracy for RDK7: 12.63 -2024-06-14 17:20:59,782 - Top 5 accuracy for RDK7: 20.73 -2024-06-14 17:27:44,560 - Top 10 accuracy for RDK7: 40.5 -2024-06-14 17:27:44,568 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 8.40 54.78 22.85 35.67 -MACCS 8.90 41.66 17.75 25.87 -RDK7 8.98 42.84 18.99 26.83 -Random 5.92 32.27 13.13 19.75 -2024-06-14 17:27:44,570 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 3.54 50.22 14.19 25.87 -MACCS 6.74 49.08 18.53 29.11 -RDK7 3.82 40.50 12.63 20.73 -Random 5.16 39.66 14.45 22.87 diff --git a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r1_log.txt b/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r1_log.txt deleted file mode 100644 index a2cc55a..0000000 --- a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r1_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 13:59:29,766 - Start process.... -2024-06-14 13:59:29,766 - Loading database.... -2024-06-14 13:59:29,804 - Processing from 0 to 500 -2024-06-14 14:27:22,150 - Processing from 500 to 1000 -2024-06-14 14:54:51,570 - Processing from 1000 to 1500 -2024-06-14 15:20:45,402 - Processing from 1500 to 2000 -2024-06-14 15:44:12,267 - Processing from 2000 to 2500 -2024-06-14 16:17:47,756 - Processing from 2500 to 3000 -2024-06-14 17:02:04,553 - Processing from 3000 to 3500 -2024-06-14 17:47:28,935 - Processing from 3500 to 4000 -2024-06-14 18:35:20,928 - Processing from 4000 to 4500 -2024-06-14 19:23:47,275 - Processing from 4500 to 5000 -2024-06-14 20:11:25,494 - Processing from 5000 to 5500 -2024-06-14 20:11:36,401 - Forward Prediction Validation -2024-06-14 20:11:44,658 - Top 1 accuracy for Random: 20.73 -2024-06-14 20:11:58,049 - Top 3 accuracy for Random: 40.48 -2024-06-14 20:12:16,291 - Top 5 accuracy for Random: 51.02 -2024-06-14 20:12:42,831 - Top 10 accuracy for Random: 63.53 -2024-06-14 20:13:49,173 - Top 1 accuracy for ECFP6: 38.8 -2024-06-14 20:14:56,223 - Top 3 accuracy for ECFP6: 63.09 -2024-06-14 20:16:06,988 - Top 5 accuracy for ECFP6: 72.39 -2024-06-14 20:17:29,872 - Top 10 accuracy for ECFP6: 77.41 -2024-06-14 20:20:57,319 - Top 1 accuracy for MACCS: 28.37 -2024-06-14 20:24:27,658 - Top 3 accuracy for MACCS: 51.68 -2024-06-14 20:28:00,343 - Top 5 accuracy for MACCS: 62.28 -2024-06-14 20:31:42,773 - Top 10 accuracy for MACCS: 73.37 -2024-06-14 20:35:16,695 - Top 1 accuracy for RDK7: 28.93 -2024-06-14 20:38:41,308 - Top 3 accuracy for RDK7: 54.56 -2024-06-14 20:42:07,339 - Top 5 accuracy for RDK7: 66.91 -2024-06-14 20:45:41,994 - Top 10 accuracy for RDK7: 76.03 -2024-06-14 20:45:42,000 - Backward Prediction Validation -2024-06-14 20:45:48,473 - Top 1 accuracy for Random: 20.19 -2024-06-14 20:46:00,472 - Top 3 accuracy for Random: 45.92 -2024-06-14 20:46:17,323 - Top 5 accuracy for Random: 60.84 -2024-06-14 20:46:43,721 - Top 10 accuracy for Random: 74.93 -2024-06-14 20:47:19,007 - Top 1 accuracy for ECFP6: 24.01 -2024-06-14 20:47:56,261 - Top 3 accuracy for ECFP6: 53.96 -2024-06-14 20:48:36,373 - Top 5 accuracy for ECFP6: 68.87 -2024-06-14 20:49:25,422 - Top 10 accuracy for ECFP6: 77.67 -2024-06-14 20:50:49,265 - Top 1 accuracy for MACCS: 21.63 -2024-06-14 20:52:24,195 - Top 3 accuracy for MACCS: 51.44 -2024-06-14 20:54:04,845 - Top 5 accuracy for MACCS: 65.07 -2024-06-14 20:55:42,438 - Top 10 accuracy for MACCS: 75.45 -2024-06-14 20:57:06,459 - Top 1 accuracy for RDK7: 19.69 -2024-06-14 20:58:37,984 - Top 3 accuracy for RDK7: 43.28 -2024-06-14 21:00:13,669 - Top 5 accuracy for RDK7: 60.76 -2024-06-14 21:01:57,367 - Top 10 accuracy for RDK7: 76.27 -2024-06-14 21:01:57,375 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 38.80 77.41 63.09 72.39 -MACCS 28.37 73.37 51.68 62.28 -RDK7 28.93 76.03 54.56 66.91 -Random 20.73 63.53 40.48 51.02 -2024-06-14 21:01:57,376 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 24.01 77.67 53.96 68.87 -MACCS 21.63 75.45 51.44 65.07 -RDK7 19.69 76.27 43.28 60.76 -Random 20.19 74.93 45.92 60.84 diff --git a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r2_log.txt b/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r2_log.txt deleted file mode 100644 index 91f4b08..0000000 --- a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r2_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 17:31:47,461 - Start process.... -2024-06-14 17:31:47,461 - Loading database.... -2024-06-14 17:31:47,492 - Processing from 0 to 500 -2024-06-14 22:37:30,676 - Processing from 500 to 1000 -2024-06-15 03:29:07,997 - Processing from 1000 to 1500 -2024-06-15 08:31:08,003 - Processing from 1500 to 2000 -2024-06-15 13:14:37,060 - Processing from 2000 to 2500 -2024-06-15 17:52:23,356 - Processing from 2500 to 3000 -2024-06-15 22:30:46,474 - Processing from 3000 to 3500 -2024-06-16 03:08:08,206 - Processing from 3500 to 4000 -2024-06-16 07:47:32,929 - Processing from 4000 to 4500 -2024-06-16 12:10:24,225 - Processing from 4500 to 5000 -2024-06-16 16:28:35,218 - Processing from 5000 to 5500 -2024-06-16 16:29:30,107 - Forward Prediction Validation -2024-06-16 16:29:35,132 - Top 1 accuracy for Random: 36.61 -2024-06-16 16:29:43,127 - Top 3 accuracy for Random: 60.06 -2024-06-16 16:29:52,078 - Top 5 accuracy for Random: 68.61 -2024-06-16 16:30:02,987 - Top 10 accuracy for Random: 73.71 -2024-06-16 16:30:17,244 - Top 1 accuracy for ECFP6: 51.88 -2024-06-16 16:30:38,099 - Top 3 accuracy for ECFP6: 69.09 -2024-06-16 16:30:58,207 - Top 5 accuracy for ECFP6: 73.45 -2024-06-16 16:31:19,016 - Top 10 accuracy for ECFP6: 75.19 -2024-06-16 16:32:05,420 - Top 1 accuracy for MACCS: 42.78 -2024-06-16 16:32:46,963 - Top 3 accuracy for MACCS: 62.48 -2024-06-16 16:33:27,906 - Top 5 accuracy for MACCS: 69.77 -2024-06-16 16:34:15,706 - Top 10 accuracy for MACCS: 74.67 -2024-06-16 16:34:59,815 - Top 1 accuracy for RDK7: 41.68 -2024-06-16 16:35:40,191 - Top 3 accuracy for RDK7: 64.51 -2024-06-16 16:36:23,651 - Top 5 accuracy for RDK7: 71.57 -2024-06-16 16:37:08,230 - Top 10 accuracy for RDK7: 75.09 -2024-06-16 16:37:08,235 - Backward Prediction Validation -2024-06-16 16:37:17,402 - Top 1 accuracy for Random: 26.75 -2024-06-16 16:37:31,248 - Top 3 accuracy for Random: 54.72 -2024-06-16 16:37:41,808 - Top 5 accuracy for Random: 67.59 -2024-06-16 16:37:56,181 - Top 10 accuracy for Random: 75.01 -2024-06-16 16:38:11,974 - Top 1 accuracy for ECFP6: 32.91 -2024-06-16 16:38:36,177 - Top 3 accuracy for ECFP6: 62.91 -2024-06-16 16:38:59,646 - Top 5 accuracy for ECFP6: 72.51 -2024-06-16 16:39:22,186 - Top 10 accuracy for ECFP6: 75.49 -2024-06-16 16:40:14,463 - Top 1 accuracy for MACCS: 28.51 -2024-06-16 16:41:04,320 - Top 3 accuracy for MACCS: 59.5 -2024-06-16 16:41:55,363 - Top 5 accuracy for MACCS: 70.27 -2024-06-16 16:42:44,997 - Top 10 accuracy for MACCS: 75.29 -2024-06-16 16:43:28,373 - Top 1 accuracy for RDK7: 26.65 -2024-06-16 16:44:17,552 - Top 3 accuracy for RDK7: 54.26 -2024-06-16 16:45:05,396 - Top 5 accuracy for RDK7: 67.83 -2024-06-16 16:45:51,768 - Top 10 accuracy for RDK7: 75.33 -2024-06-16 16:45:51,774 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 51.88 75.19 69.09 73.45 -MACCS 42.78 74.67 62.48 69.77 -RDK7 41.68 75.09 64.51 71.57 -Random 36.61 73.71 60.06 68.61 -2024-06-16 16:45:51,775 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 32.91 75.49 62.91 72.51 -MACCS 28.51 75.29 59.50 70.27 -RDK7 26.65 75.33 54.26 67.83 -Random 26.75 75.01 54.72 67.59 diff --git a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r3_log.txt b/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r3_log.txt deleted file mode 100644 index 550d178..0000000 --- a/Data/DPO/USPTO_50K/Hydrogen/Log/rules_r3_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 17:32:07,913 - Start process.... -2024-06-14 17:32:07,913 - Loading database.... -2024-06-14 17:32:07,936 - Processing from 0 to 500 -2024-06-15 05:14:06,813 - Processing from 500 to 1000 -2024-06-15 16:47:08,320 - Processing from 1000 to 1500 -2024-06-16 03:40:25,161 - Processing from 1500 to 2000 -2024-06-16 14:17:55,868 - Processing from 2000 to 2500 -2024-06-16 23:56:39,721 - Processing from 2500 to 3000 -2024-06-17 08:57:55,646 - Processing from 3000 to 3500 -2024-06-17 19:08:55,311 - Processing from 3500 to 4000 -2024-06-18 04:09:39,559 - Processing from 4000 to 4500 -2024-06-18 13:09:10,956 - Processing from 4500 to 5000 -2024-06-18 22:01:05,195 - Processing from 5000 to 5500 -2024-06-18 22:03:15,197 - Forward Prediction Validation -2024-06-18 22:03:19,533 - Top 1 accuracy for Random: 38.28 -2024-06-18 22:03:26,014 - Top 3 accuracy for Random: 58.36 -2024-06-18 22:03:33,435 - Top 5 accuracy for Random: 63.23 -2024-06-18 22:03:41,555 - Top 10 accuracy for Random: 66.47 -2024-06-18 22:03:51,266 - Top 1 accuracy for ECFP6: 49.58 -2024-06-18 22:04:03,137 - Top 3 accuracy for ECFP6: 63.47 -2024-06-18 22:04:15,869 - Top 5 accuracy for ECFP6: 65.75 -2024-06-18 22:04:29,507 - Top 10 accuracy for ECFP6: 66.75 -2024-06-18 22:04:52,009 - Top 1 accuracy for MACCS: 42.26 -2024-06-18 22:05:16,692 - Top 3 accuracy for MACCS: 58.76 -2024-06-18 22:05:42,272 - Top 5 accuracy for MACCS: 63.51 -2024-06-18 22:06:08,693 - Top 10 accuracy for MACCS: 66.55 -2024-06-18 22:06:31,659 - Top 1 accuracy for RDK7: 41.5 -2024-06-18 22:06:56,522 - Top 3 accuracy for RDK7: 60.46 -2024-06-18 22:07:22,419 - Top 5 accuracy for RDK7: 64.99 -2024-06-18 22:07:49,144 - Top 10 accuracy for RDK7: 66.63 -2024-06-18 22:07:49,158 - Backward Prediction Validation -2024-06-18 22:07:53,596 - Top 1 accuracy for Random: 29.61 -2024-06-18 22:08:00,836 - Top 3 accuracy for Random: 55.14 -2024-06-18 22:08:09,623 - Top 5 accuracy for Random: 63.81 -2024-06-18 22:08:19,356 - Top 10 accuracy for Random: 66.83 -2024-06-18 22:08:30,607 - Top 1 accuracy for ECFP6: 37.41 -2024-06-18 22:08:44,784 - Top 3 accuracy for ECFP6: 61.22 -2024-06-18 22:09:00,404 - Top 5 accuracy for ECFP6: 65.79 -2024-06-18 22:09:16,979 - Top 10 accuracy for ECFP6: 66.99 -2024-06-18 22:09:44,466 - Top 1 accuracy for MACCS: 31.53 -2024-06-18 22:10:15,018 - Top 3 accuracy for MACCS: 57.66 -2024-06-18 22:10:46,903 - Top 5 accuracy for MACCS: 65.01 -2024-06-18 22:11:19,718 - Top 10 accuracy for MACCS: 66.91 -2024-06-18 22:11:47,513 - Top 1 accuracy for RDK7: 30.27 -2024-06-18 22:12:18,058 - Top 3 accuracy for RDK7: 55.06 -2024-06-18 22:12:50,046 - Top 5 accuracy for RDK7: 64.05 -2024-06-18 22:13:23,114 - Top 10 accuracy for RDK7: 66.93 -2024-06-18 22:13:23,119 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 49.58 66.75 63.47 65.75 -MACCS 42.26 66.55 58.76 63.51 -RDK7 41.50 66.63 60.46 64.99 -Random 38.28 66.47 58.36 63.23 -2024-06-18 22:13:23,121 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 37.41 66.99 61.22 65.79 -MACCS 31.53 66.91 57.66 65.01 -RDK7 30.27 66.93 55.06 64.05 -Random 29.61 66.83 55.14 63.81 diff --git a/Data/DPO/USPTO_50K/Hydrogen/USPTO_50K_pipeline_log.log b/Data/DPO/USPTO_50K/Hydrogen/USPTO_50K_pipeline_log.log deleted file mode 100644 index 563f12e..0000000 --- a/Data/DPO/USPTO_50K/Hydrogen/USPTO_50K_pipeline_log.log +++ /dev/null @@ -1,87 +0,0 @@ -2024-06-10 11:15:01,505 - INFO - Processing data USPTO_50K with 4 cpus -2024-06-10 11:15:05,399 - INFO - Fixing hydrogen for batch 1/81. -2024-06-10 11:15:10,278 - INFO - Fixing hydrogen for batch 2/81. -2024-06-10 11:15:15,827 - INFO - Fixing hydrogen for batch 3/81. -2024-06-10 11:15:24,268 - INFO - Fixing hydrogen for batch 4/81. -2024-06-10 11:15:32,827 - INFO - Fixing hydrogen for batch 5/81. -2024-06-10 11:15:40,431 - INFO - Fixing hydrogen for batch 6/81. -2024-06-10 11:15:47,763 - INFO - Fixing hydrogen for batch 7/81. -2024-06-10 11:15:55,420 - INFO - Fixing hydrogen for batch 8/81. -2024-06-10 11:16:03,022 - INFO - Fixing hydrogen for batch 9/81. -2024-06-10 11:16:10,391 - INFO - Fixing hydrogen for batch 10/81. -2024-06-10 11:16:17,973 - INFO - Fixing hydrogen for batch 11/81. -2024-06-10 11:16:25,168 - INFO - Fixing hydrogen for batch 12/81. -2024-06-10 11:16:32,338 - INFO - Fixing hydrogen for batch 13/81. -2024-06-10 11:16:39,769 - INFO - Fixing hydrogen for batch 14/81. -2024-06-10 11:16:47,303 - INFO - Fixing hydrogen for batch 15/81. -2024-06-10 11:16:54,309 - INFO - Fixing hydrogen for batch 16/81. -2024-06-10 11:17:01,596 - INFO - Fixing hydrogen for batch 17/81. -2024-06-10 11:17:08,528 - INFO - Fixing hydrogen for batch 18/81. -2024-06-10 11:17:15,868 - INFO - Fixing hydrogen for batch 19/81. -2024-06-10 11:17:23,118 - INFO - Fixing hydrogen for batch 20/81. -2024-06-10 11:17:30,860 - INFO - Fixing hydrogen for batch 21/81. -2024-06-10 11:17:40,903 - INFO - Fixing hydrogen for batch 22/81. -2024-06-10 11:17:49,188 - INFO - Fixing hydrogen for batch 23/81. -2024-06-10 11:17:56,532 - INFO - Fixing hydrogen for batch 24/81. -2024-06-10 11:18:05,165 - INFO - Fixing hydrogen for batch 25/81. -2024-06-10 11:18:13,878 - INFO - Fixing hydrogen for batch 26/81. -2024-06-10 11:18:21,133 - INFO - Fixing hydrogen for batch 27/81. -2024-06-10 11:18:28,050 - INFO - Fixing hydrogen for batch 28/81. -2024-06-10 11:18:35,547 - INFO - Fixing hydrogen for batch 29/81. -2024-06-10 11:18:42,669 - INFO - Fixing hydrogen for batch 30/81. -2024-06-10 11:18:50,235 - INFO - Fixing hydrogen for batch 31/81. -2024-06-10 11:18:57,983 - INFO - Fixing hydrogen for batch 32/81. -2024-06-10 11:19:08,481 - INFO - Fixing hydrogen for batch 33/81. -2024-06-10 11:19:16,900 - INFO - Fixing hydrogen for batch 34/81. -2024-06-10 11:19:25,054 - INFO - Fixing hydrogen for batch 35/81. -2024-06-10 11:19:32,008 - INFO - Fixing hydrogen for batch 36/81. -2024-06-10 11:19:39,241 - INFO - Fixing hydrogen for batch 37/81. -2024-06-10 11:19:46,367 - INFO - Fixing hydrogen for batch 38/81. -2024-06-10 11:19:54,258 - INFO - Fixing hydrogen for batch 39/81. -2024-06-10 11:20:02,099 - INFO - Fixing hydrogen for batch 40/81. -2024-06-10 11:20:09,693 - INFO - Fixing hydrogen for batch 41/81. -2024-06-10 11:20:17,561 - INFO - Fixing hydrogen for batch 42/81. -2024-06-10 11:20:25,666 - INFO - Fixing hydrogen for batch 43/81. -2024-06-10 11:20:34,670 - INFO - Fixing hydrogen for batch 44/81. -2024-06-10 11:20:42,190 - INFO - Fixing hydrogen for batch 45/81. -2024-06-10 11:20:50,092 - INFO - Fixing hydrogen for batch 46/81. -2024-06-10 11:20:58,171 - INFO - Fixing hydrogen for batch 47/81. -2024-06-10 11:21:05,622 - INFO - Fixing hydrogen for batch 48/81. -2024-06-10 11:21:13,255 - INFO - Fixing hydrogen for batch 49/81. -2024-06-10 11:21:20,764 - INFO - Fixing hydrogen for batch 50/81. -2024-06-10 11:21:28,488 - INFO - Fixing hydrogen for batch 51/81. -2024-06-10 11:21:37,051 - INFO - Fixing hydrogen for batch 52/81. -2024-06-10 11:21:44,651 - INFO - Fixing hydrogen for batch 53/81. -2024-06-10 11:21:52,690 - INFO - Fixing hydrogen for batch 54/81. -2024-06-10 11:22:01,854 - INFO - Fixing hydrogen for batch 55/81. -2024-06-10 11:22:10,180 - INFO - Fixing hydrogen for batch 56/81. -2024-06-10 11:22:19,709 - INFO - Fixing hydrogen for batch 57/81. -2024-06-10 11:22:27,736 - INFO - Fixing hydrogen for batch 58/81. -2024-06-10 11:22:35,619 - INFO - Fixing hydrogen for batch 59/81. -2024-06-10 11:22:43,253 - INFO - Fixing hydrogen for batch 60/81. -2024-06-10 11:22:51,194 - INFO - Fixing hydrogen for batch 61/81. -2024-06-10 11:22:59,395 - INFO - Fixing hydrogen for batch 62/81. -2024-06-10 11:23:07,782 - INFO - Fixing hydrogen for batch 63/81. -2024-06-10 11:23:14,841 - INFO - Fixing hydrogen for batch 64/81. -2024-06-10 11:23:21,772 - INFO - Fixing hydrogen for batch 65/81. -2024-06-10 11:23:29,047 - INFO - Fixing hydrogen for batch 66/81. -2024-06-10 11:23:36,467 - INFO - Fixing hydrogen for batch 67/81. -2024-06-10 11:23:43,810 - INFO - Fixing hydrogen for batch 68/81. -2024-06-10 11:23:51,233 - INFO - Fixing hydrogen for batch 69/81. -2024-06-10 11:23:59,276 - INFO - Fixing hydrogen for batch 70/81. -2024-06-10 11:24:06,713 - INFO - Fixing hydrogen for batch 71/81. -2024-06-10 11:24:13,732 - INFO - Fixing hydrogen for batch 72/81. -2024-06-10 11:24:21,119 - INFO - Fixing hydrogen for batch 73/81. -2024-06-10 11:24:28,265 - INFO - Fixing hydrogen for batch 74/81. -2024-06-10 11:24:35,179 - INFO - Fixing hydrogen for batch 75/81. -2024-06-10 11:24:42,583 - INFO - Fixing hydrogen for batch 76/81. -2024-06-10 11:24:49,155 - INFO - Fixing hydrogen for batch 77/81. -2024-06-10 11:24:55,796 - INFO - Fixing hydrogen for batch 78/81. -2024-06-10 11:25:02,919 - INFO - Fixing hydrogen for batch 79/81. -2024-06-10 11:25:09,889 - INFO - Fixing hydrogen for batch 80/81. -2024-06-10 11:25:11,040 - INFO - Fixing hydrogen for batch 81/81. -2024-06-10 11:25:55,169 - INFO - Combining and save data -2024-06-10 11:25:55,170 - INFO - Number of correct mappers:34584 -2024-06-10 11:25:55,170 - INFO - Number of incorrect mappers:5238 -2024-06-10 11:25:55,170 - INFO - Number of uncertain hydrogen:190 -2024-06-10 11:26:31,206 - INFO - Execution time: 689.70 seconds diff --git a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r0_log.txt b/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r0_log.txt deleted file mode 100644 index edae72b..0000000 --- a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r0_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 13:57:30,578 - Start process.... -2024-06-14 13:57:30,578 - Loading database.... -2024-06-14 13:57:30,600 - Processing from 0 to 500 -2024-06-14 14:04:48,618 - Processing from 500 to 1000 -2024-06-14 14:12:22,625 - Processing from 1000 to 1500 -2024-06-14 14:19:55,805 - Processing from 1500 to 2000 -2024-06-14 14:27:10,047 - Processing from 2000 to 2500 -2024-06-14 14:34:23,253 - Processing from 2500 to 3000 -2024-06-14 14:41:00,019 - Processing from 3000 to 3500 -2024-06-14 14:47:59,231 - Processing from 3500 to 4000 -2024-06-14 14:55:36,650 - Processing from 4000 to 4500 -2024-06-14 15:03:16,915 - Processing from 4500 to 5000 -2024-06-14 15:09:56,966 - Processing from 5000 to 5500 -2024-06-14 15:09:58,809 - Forward Prediction Validation -2024-06-14 15:10:03,273 - Top 1 accuracy for Random: 3.02 -2024-06-14 15:10:10,217 - Top 3 accuracy for Random: 5.4 -2024-06-14 15:10:18,825 - Top 5 accuracy for Random: 6.66 -2024-06-14 15:10:30,539 - Top 10 accuracy for Random: 7.64 -2024-06-14 15:10:47,388 - Top 1 accuracy for ECFP6: 3.04 -2024-06-14 15:11:07,556 - Top 3 accuracy for ECFP6: 5.88 -2024-06-14 15:11:26,043 - Top 5 accuracy for ECFP6: 7.16 -2024-06-14 15:11:48,855 - Top 10 accuracy for ECFP6: 7.94 -2024-06-14 15:12:29,752 - Top 1 accuracy for MACCS: 4.16 -2024-06-14 15:13:13,080 - Top 3 accuracy for MACCS: 6.92 -2024-06-14 15:13:57,838 - Top 5 accuracy for MACCS: 7.62 -2024-06-14 15:14:46,292 - Top 10 accuracy for MACCS: 7.96 -2024-06-14 15:15:28,930 - Top 1 accuracy for RDK7: 2.4 -2024-06-14 15:16:16,204 - Top 3 accuracy for RDK7: 5.02 -2024-06-14 15:17:03,328 - Top 5 accuracy for RDK7: 6.3 -2024-06-14 15:17:53,806 - Top 10 accuracy for RDK7: 7.62 -2024-06-14 15:17:53,811 - Backward Prediction Validation -2024-06-14 15:17:57,894 - Top 1 accuracy for Random: 0.88 -2024-06-14 15:18:04,991 - Top 3 accuracy for Random: 2.32 -2024-06-14 15:18:13,288 - Top 5 accuracy for Random: 3.58 -2024-06-14 15:18:23,192 - Top 10 accuracy for Random: 5.2 -2024-06-14 15:18:39,013 - Top 1 accuracy for ECFP6: 0.56 -2024-06-14 15:18:58,398 - Top 3 accuracy for ECFP6: 1.54 -2024-06-14 15:19:17,096 - Top 5 accuracy for ECFP6: 2.52 -2024-06-14 15:19:40,527 - Top 10 accuracy for ECFP6: 4.58 -2024-06-14 15:20:24,097 - Top 1 accuracy for MACCS: 1.68 -2024-06-14 15:21:09,067 - Top 3 accuracy for MACCS: 4.48 -2024-06-14 15:21:56,635 - Top 5 accuracy for MACCS: 6.0 -2024-06-14 15:22:47,371 - Top 10 accuracy for MACCS: 7.46 -2024-06-14 15:23:33,549 - Top 1 accuracy for RDK7: 0.68 -2024-06-14 15:24:20,853 - Top 3 accuracy for RDK7: 1.66 -2024-06-14 15:25:10,925 - Top 5 accuracy for RDK7: 2.48 -2024-06-14 15:26:02,038 - Top 10 accuracy for RDK7: 4.38 -2024-06-14 15:26:02,044 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 3.04 7.94 5.88 7.16 -MACCS 4.16 7.96 6.92 7.62 -RDK7 2.40 7.62 5.02 6.30 -Random 3.02 7.64 5.40 6.66 -2024-06-14 15:26:02,046 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 0.56 4.58 1.54 2.52 -MACCS 1.68 7.46 4.48 6.00 -RDK7 0.68 4.38 1.66 2.48 -Random 0.88 5.20 2.32 3.58 diff --git a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r1_log.txt b/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r1_log.txt deleted file mode 100644 index 2511e94..0000000 --- a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r1_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 13:59:11,071 - Start process.... -2024-06-14 13:59:11,071 - Loading database.... -2024-06-14 13:59:11,109 - Processing from 0 to 500 -2024-06-14 14:28:20,349 - Processing from 500 to 1000 -2024-06-14 14:57:18,208 - Processing from 1000 to 1500 -2024-06-14 15:24:03,178 - Processing from 1500 to 2000 -2024-06-14 15:48:26,544 - Processing from 2000 to 2500 -2024-06-14 16:27:43,462 - Processing from 2500 to 3000 -2024-06-14 17:13:19,668 - Processing from 3000 to 3500 -2024-06-14 18:02:28,586 - Processing from 3500 to 4000 -2024-06-14 18:52:02,549 - Processing from 4000 to 4500 -2024-06-14 19:42:04,177 - Processing from 4500 to 5000 -2024-06-14 20:31:18,701 - Processing from 5000 to 5500 -2024-06-14 20:31:29,210 - Forward Prediction Validation -2024-06-14 20:31:34,086 - Top 1 accuracy for Random: 6.06 -2024-06-14 20:31:39,555 - Top 3 accuracy for Random: 7.44 -2024-06-14 20:31:45,663 - Top 5 accuracy for Random: 7.5 -2024-06-14 20:31:51,144 - Top 10 accuracy for Random: 7.5 -2024-06-14 20:31:57,480 - Top 1 accuracy for ECFP6: 6.3 -2024-06-14 20:32:04,324 - Top 3 accuracy for ECFP6: 7.5 -2024-06-14 20:32:12,328 - Top 5 accuracy for ECFP6: 7.5 -2024-06-14 20:32:20,657 - Top 10 accuracy for ECFP6: 7.5 -2024-06-14 20:32:30,310 - Top 1 accuracy for MACCS: 6.36 -2024-06-14 20:32:40,403 - Top 3 accuracy for MACCS: 7.44 -2024-06-14 20:32:50,617 - Top 5 accuracy for MACCS: 7.5 -2024-06-14 20:33:02,110 - Top 10 accuracy for MACCS: 7.5 -2024-06-14 20:33:13,865 - Top 1 accuracy for RDK7: 6.04 -2024-06-14 20:33:25,846 - Top 3 accuracy for RDK7: 7.46 -2024-06-14 20:33:37,857 - Top 5 accuracy for RDK7: 7.5 -2024-06-14 20:33:49,270 - Top 10 accuracy for RDK7: 7.5 -2024-06-14 20:33:49,279 - Backward Prediction Validation -2024-06-14 20:33:55,227 - Top 1 accuracy for Random: 2.6 -2024-06-14 20:34:01,298 - Top 3 accuracy for Random: 5.84 -2024-06-14 20:34:08,586 - Top 5 accuracy for Random: 6.98 -2024-06-14 20:34:16,013 - Top 10 accuracy for Random: 7.46 -2024-06-14 20:34:22,830 - Top 1 accuracy for ECFP6: 1.66 -2024-06-14 20:34:30,381 - Top 3 accuracy for ECFP6: 5.46 -2024-06-14 20:34:38,480 - Top 5 accuracy for ECFP6: 6.98 -2024-06-14 20:34:46,939 - Top 10 accuracy for ECFP6: 7.44 -2024-06-14 20:34:59,340 - Top 1 accuracy for MACCS: 3.14 -2024-06-14 20:35:13,090 - Top 3 accuracy for MACCS: 6.42 -2024-06-14 20:35:26,081 - Top 5 accuracy for MACCS: 7.18 -2024-06-14 20:35:39,432 - Top 10 accuracy for MACCS: 7.5 -2024-06-14 20:35:52,487 - Top 1 accuracy for RDK7: 2.32 -2024-06-14 20:36:05,405 - Top 3 accuracy for RDK7: 5.72 -2024-06-14 20:36:18,727 - Top 5 accuracy for RDK7: 7.1 -2024-06-14 20:36:32,520 - Top 10 accuracy for RDK7: 7.48 -2024-06-14 20:36:32,527 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 6.30 7.5 7.50 7.5 -MACCS 6.36 7.5 7.44 7.5 -RDK7 6.04 7.5 7.46 7.5 -Random 6.06 7.5 7.44 7.5 -2024-06-14 20:36:32,528 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 1.66 7.44 5.46 6.98 -MACCS 3.14 7.50 6.42 7.18 -RDK7 2.32 7.48 5.72 7.10 -Random 2.60 7.46 5.84 6.98 diff --git a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r2_log.txt b/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r2_log.txt deleted file mode 100644 index 933536f..0000000 --- a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r2_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 15:56:50,391 - Start process.... -2024-06-14 15:56:50,391 - Loading database.... -2024-06-14 15:56:50,415 - Processing from 0 to 500 -2024-06-14 21:07:01,711 - Processing from 500 to 1000 -2024-06-15 02:00:37,117 - Processing from 1000 to 1500 -2024-06-15 07:01:27,742 - Processing from 1500 to 2000 -2024-06-15 11:54:33,939 - Processing from 2000 to 2500 -2024-06-15 16:34:43,355 - Processing from 2500 to 3000 -2024-06-15 21:13:52,237 - Processing from 3000 to 3500 -2024-06-16 01:55:53,477 - Processing from 3500 to 4000 -2024-06-16 06:37:56,147 - Processing from 4000 to 4500 -2024-06-16 11:07:16,352 - Processing from 4500 to 5000 -2024-06-16 15:31:07,232 - Processing from 5000 to 5500 -2024-06-16 15:32:04,502 - Forward Prediction Validation -2024-06-16 15:32:08,066 - Top 1 accuracy for Random: 5.54 -2024-06-16 15:32:11,320 - Top 3 accuracy for Random: 6.38 -2024-06-16 15:32:15,045 - Top 5 accuracy for Random: 6.44 -2024-06-16 15:32:18,275 - Top 10 accuracy for Random: 6.44 -2024-06-16 15:32:22,538 - Top 1 accuracy for ECFP6: 5.68 -2024-06-16 15:32:27,227 - Top 3 accuracy for ECFP6: 6.44 -2024-06-16 15:32:31,549 - Top 5 accuracy for ECFP6: 6.44 -2024-06-16 15:32:35,620 - Top 10 accuracy for ECFP6: 6.44 -2024-06-16 15:32:41,044 - Top 1 accuracy for MACCS: 5.72 -2024-06-16 15:32:46,085 - Top 3 accuracy for MACCS: 6.44 -2024-06-16 15:32:51,959 - Top 5 accuracy for MACCS: 6.44 -2024-06-16 15:32:58,439 - Top 10 accuracy for MACCS: 6.44 -2024-06-16 15:33:03,963 - Top 1 accuracy for RDK7: 5.46 -2024-06-16 15:33:10,122 - Top 3 accuracy for RDK7: 6.42 -2024-06-16 15:33:16,864 - Top 5 accuracy for RDK7: 6.44 -2024-06-16 15:33:24,391 - Top 10 accuracy for RDK7: 6.44 -2024-06-16 15:33:24,397 - Backward Prediction Validation -2024-06-16 15:33:27,538 - Top 1 accuracy for Random: 3.02 -2024-06-16 15:33:31,363 - Top 3 accuracy for Random: 5.68 -2024-06-16 15:33:36,156 - Top 5 accuracy for Random: 6.28 -2024-06-16 15:33:40,181 - Top 10 accuracy for Random: 6.44 -2024-06-16 15:33:44,726 - Top 1 accuracy for ECFP6: 2.54 -2024-06-16 15:33:50,605 - Top 3 accuracy for ECFP6: 5.66 -2024-06-16 15:33:55,579 - Top 5 accuracy for ECFP6: 6.26 -2024-06-16 15:34:01,588 - Top 10 accuracy for ECFP6: 6.44 -2024-06-16 15:34:08,473 - Top 1 accuracy for MACCS: 3.7 -2024-06-16 15:34:16,498 - Top 3 accuracy for MACCS: 6.1 -2024-06-16 15:34:23,476 - Top 5 accuracy for MACCS: 6.34 -2024-06-16 15:34:31,281 - Top 10 accuracy for MACCS: 6.44 -2024-06-16 15:34:37,983 - Top 1 accuracy for RDK7: 2.92 -2024-06-16 15:34:45,193 - Top 3 accuracy for RDK7: 5.86 -2024-06-16 15:34:52,718 - Top 5 accuracy for RDK7: 6.3 -2024-06-16 15:35:01,165 - Top 10 accuracy for RDK7: 6.44 -2024-06-16 15:35:01,171 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 5.68 6.44 6.44 6.44 -MACCS 5.72 6.44 6.44 6.44 -RDK7 5.46 6.44 6.42 6.44 -Random 5.54 6.44 6.38 6.44 -2024-06-16 15:35:01,172 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 2.54 6.44 5.66 6.26 -MACCS 3.70 6.44 6.10 6.34 -RDK7 2.92 6.44 5.86 6.30 -Random 3.02 6.44 5.68 6.28 diff --git a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r3_log.txt b/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r3_log.txt deleted file mode 100644 index 39cd578..0000000 --- a/Data/DPO/USPTO_50K/Non_hydrogen/Log/rules_r3_log.txt +++ /dev/null @@ -1,61 +0,0 @@ -2024-06-14 15:56:44,503 - Start process.... -2024-06-14 15:56:44,503 - Loading database.... -2024-06-14 15:56:44,540 - Processing from 0 to 500 -2024-06-15 03:40:32,609 - Processing from 500 to 1000 -2024-06-15 15:21:01,349 - Processing from 1000 to 1500 -2024-06-16 02:16:51,705 - Processing from 1500 to 2000 -2024-06-16 13:00:33,045 - Processing from 2000 to 2500 -2024-06-16 22:49:50,818 - Processing from 2500 to 3000 -2024-06-17 07:53:01,201 - Processing from 3000 to 3500 -2024-06-17 18:05:10,221 - Processing from 3500 to 4000 -2024-06-18 03:07:37,264 - Processing from 4000 to 4500 -2024-06-18 12:09:20,626 - Processing from 4500 to 5000 -2024-06-18 21:06:40,255 - Processing from 5000 to 5500 -2024-06-18 21:08:36,074 - Forward Prediction Validation -2024-06-18 21:08:38,813 - Top 1 accuracy for Random: 4.34 -2024-06-18 21:08:41,675 - Top 3 accuracy for Random: 4.78 -2024-06-18 21:08:44,522 - Top 5 accuracy for Random: 4.78 -2024-06-18 21:08:47,388 - Top 10 accuracy for Random: 4.78 -2024-06-18 21:08:50,480 - Top 1 accuracy for ECFP6: 4.4 -2024-06-18 21:08:53,768 - Top 3 accuracy for ECFP6: 4.78 -2024-06-18 21:08:57,039 - Top 5 accuracy for ECFP6: 4.78 -2024-06-18 21:09:00,259 - Top 10 accuracy for ECFP6: 4.78 -2024-06-18 21:09:04,201 - Top 1 accuracy for MACCS: 4.48 -2024-06-18 21:09:08,437 - Top 3 accuracy for MACCS: 4.78 -2024-06-18 21:09:12,581 - Top 5 accuracy for MACCS: 4.78 -2024-06-18 21:09:17,021 - Top 10 accuracy for MACCS: 4.78 -2024-06-18 21:09:21,004 - Top 1 accuracy for RDK7: 4.24 -2024-06-18 21:09:25,294 - Top 3 accuracy for RDK7: 4.78 -2024-06-18 21:09:29,528 - Top 5 accuracy for RDK7: 4.78 -2024-06-18 21:09:33,651 - Top 10 accuracy for RDK7: 4.78 -2024-06-18 21:09:33,656 - Backward Prediction Validation -2024-06-18 21:09:36,555 - Top 1 accuracy for Random: 3.08 -2024-06-18 21:09:39,505 - Top 3 accuracy for Random: 4.58 -2024-06-18 21:09:42,545 - Top 5 accuracy for Random: 4.78 -2024-06-18 21:09:45,577 - Top 10 accuracy for Random: 4.78 -2024-06-18 21:09:48,869 - Top 1 accuracy for ECFP6: 2.78 -2024-06-18 21:09:52,668 - Top 3 accuracy for ECFP6: 4.54 -2024-06-18 21:09:56,321 - Top 5 accuracy for ECFP6: 4.74 -2024-06-18 21:09:59,960 - Top 10 accuracy for ECFP6: 4.78 -2024-06-18 21:10:04,484 - Top 1 accuracy for MACCS: 3.1 -2024-06-18 21:10:09,502 - Top 3 accuracy for MACCS: 4.62 -2024-06-18 21:10:14,712 - Top 5 accuracy for MACCS: 4.74 -2024-06-18 21:10:19,611 - Top 10 accuracy for MACCS: 4.78 -2024-06-18 21:10:24,419 - Top 1 accuracy for RDK7: 3.04 -2024-06-18 21:10:29,430 - Top 3 accuracy for RDK7: 4.62 -2024-06-18 21:10:34,524 - Top 5 accuracy for RDK7: 4.78 -2024-06-18 21:10:39,928 - Top 10 accuracy for RDK7: 4.78 -2024-06-18 21:10:39,933 - Forward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 4.40 4.78 4.78 4.78 -MACCS 4.48 4.78 4.78 4.78 -RDK7 4.24 4.78 4.78 4.78 -Random 4.34 4.78 4.78 4.78 -2024-06-18 21:10:39,934 - Backward Prediction Results Matrix: -Top K Top 1 Top 10 Top 3 Top 5 -Scoring Function -ECFP6 2.78 4.78 4.54 4.74 -MACCS 3.10 4.78 4.62 4.74 -RDK7 3.04 4.78 4.62 4.78 -Random 3.08 4.78 4.58 4.78 diff --git a/Data/DPO/USPTO_50K/Non_hydrogen/USPTO_50K_pipeline_log.log b/Data/DPO/USPTO_50K/Non_hydrogen/USPTO_50K_pipeline_log.log deleted file mode 100644 index 8c61b73..0000000 --- a/Data/DPO/USPTO_50K/Non_hydrogen/USPTO_50K_pipeline_log.log +++ /dev/null @@ -1,6 +0,0 @@ -2024-06-10 11:15:16,713 - INFO - Processing data USPTO_50K with 4 cpus -2024-06-10 11:24:55,797 - INFO - Combining and save data -2024-06-10 11:24:55,797 - INFO - Number of correct mappers:34774 -2024-06-10 11:24:55,797 - INFO - Number of incorrect mappers:5238 -2024-06-10 11:24:55,797 - INFO - Number of uncertain hydrogen:0 -2024-06-10 11:25:25,645 - INFO - Execution time: 608.93 seconds diff --git a/Data/DPO/USPTO_balance/Complete/USPTO_balance_pipeline.log b/Data/DPO/USPTO_balance/Complete/USPTO_balance_pipeline.log deleted file mode 100644 index 8dc1b2d..0000000 --- a/Data/DPO/USPTO_balance/Complete/USPTO_balance_pipeline.log +++ /dev/null @@ -1,47 +0,0 @@ -2024-06-25 08:58:01,909 - INFO - Processing data USPTO_balance with 4 cpus -2024-06-25 08:58:10,510 - INFO - Fixing hydrogen for batch 1/41. -2024-06-25 08:58:24,890 - INFO - Fixing hydrogen for batch 2/41. -2024-06-25 08:58:41,024 - INFO - Fixing hydrogen for batch 3/41. -2024-06-25 08:58:57,364 - INFO - Fixing hydrogen for batch 4/41. -2024-06-25 08:59:28,218 - INFO - Fixing hydrogen for batch 5/41. -2024-06-25 08:59:42,362 - INFO - Fixing hydrogen for batch 6/41. -2024-06-25 09:00:00,112 - INFO - Fixing hydrogen for batch 7/41. -2024-06-25 09:00:16,945 - INFO - Fixing hydrogen for batch 8/41. -2024-06-25 09:00:31,653 - INFO - Fixing hydrogen for batch 9/41. -2024-06-25 09:00:59,320 - INFO - Fixing hydrogen for batch 10/41. -2024-06-25 09:01:14,753 - INFO - Fixing hydrogen for batch 11/41. -2024-06-25 09:01:30,425 - INFO - Fixing hydrogen for batch 12/41. -2024-06-25 09:01:45,238 - INFO - Fixing hydrogen for batch 13/41. -2024-06-25 09:02:00,173 - INFO - Fixing hydrogen for batch 14/41. -2024-06-25 09:02:17,687 - INFO - Fixing hydrogen for batch 15/41. -2024-06-25 09:02:35,650 - INFO - Fixing hydrogen for batch 16/41. -2024-06-25 09:02:51,374 - INFO - Fixing hydrogen for batch 17/41. -2024-06-25 09:03:08,713 - INFO - Fixing hydrogen for batch 18/41. -2024-06-25 09:03:25,082 - INFO - Fixing hydrogen for batch 19/41. -2024-06-25 09:03:40,441 - INFO - Fixing hydrogen for batch 20/41. -2024-06-25 09:03:56,796 - INFO - Fixing hydrogen for batch 21/41. -2024-06-25 09:04:12,166 - INFO - Fixing hydrogen for batch 22/41. -2024-06-25 09:04:27,703 - INFO - Fixing hydrogen for batch 23/41. -2024-06-25 09:04:45,005 - INFO - Fixing hydrogen for batch 24/41. -2024-06-25 09:04:58,841 - INFO - Fixing hydrogen for batch 25/41. -2024-06-25 09:05:14,692 - INFO - Fixing hydrogen for batch 26/41. -2024-06-25 09:05:29,991 - INFO - Fixing hydrogen for batch 27/41. -2024-06-25 09:05:43,656 - INFO - Fixing hydrogen for batch 28/41. -2024-06-25 09:05:57,905 - INFO - Fixing hydrogen for batch 29/41. -2024-06-25 09:06:12,887 - INFO - Fixing hydrogen for batch 30/41. -2024-06-25 09:06:27,649 - INFO - Fixing hydrogen for batch 31/41. -2024-06-25 09:06:42,950 - INFO - Fixing hydrogen for batch 32/41. -2024-06-25 09:06:58,385 - INFO - Fixing hydrogen for batch 33/41. -2024-06-25 09:07:13,270 - INFO - Fixing hydrogen for batch 34/41. -2024-06-25 09:07:29,521 - INFO - Fixing hydrogen for batch 35/41. -2024-06-25 09:07:44,116 - INFO - Fixing hydrogen for batch 36/41. -2024-06-25 09:07:57,989 - INFO - Fixing hydrogen for batch 37/41. -2024-06-25 09:08:13,116 - INFO - Fixing hydrogen for batch 38/41. -2024-06-25 09:08:29,922 - INFO - Fixing hydrogen for batch 39/41. -2024-06-25 09:08:48,527 - INFO - Fixing hydrogen for batch 40/41. -2024-06-25 09:08:54,046 - INFO - Fixing hydrogen for batch 41/41. -2024-06-25 09:09:49,063 - INFO - Combining and save data -2024-06-25 09:09:49,063 - INFO - Number of correct mappers:33700 -2024-06-25 09:09:49,063 - INFO - Number of incorrect mappers:5412 -2024-06-25 09:09:49,063 - INFO - Number of uncertain hydrogen:900 -2024-06-25 09:10:19,197 - INFO - Execution time: 737.29 seconds diff --git a/Data/DPO/USPTO_balance/Raw/USPTO_balance_pipeline.log b/Data/DPO/USPTO_balance/Raw/USPTO_balance_pipeline.log deleted file mode 100644 index ed59631..0000000 --- a/Data/DPO/USPTO_balance/Raw/USPTO_balance_pipeline.log +++ /dev/null @@ -1,6 +0,0 @@ -2024-06-25 15:43:57,335 - INFO - Processing data USPTO_balance with 4 cpus -2024-06-25 15:52:07,139 - INFO - Combining and save data -2024-06-25 15:52:07,139 - INFO - Number of correct mappers:34600 -2024-06-25 15:52:07,139 - INFO - Number of incorrect mappers:5412 -2024-06-25 15:52:07,139 - INFO - Number of uncertain hydrogen:0 -2024-06-25 15:52:36,522 - INFO - Execution time: 519.19 seconds diff --git a/Data/DPO/USPTO_balance/aam_log.txt b/Data/DPO/USPTO_balance/aam_log.txt deleted file mode 100644 index 1463abb..0000000 --- a/Data/DPO/USPTO_balance/aam_log.txt +++ /dev/null @@ -1,3027 +0,0 @@ -2024-06-24 15:21:54,449 - INFO - Starting processing of Data/DPO/USPTO_balance/USPTO_50K_reactions.json.gz -2024-06-24 15:21:54,545 - INFO - Starting consensus mapping for Data/DPO/USPTO_balance/USPTO_50K_reactions.json.gz using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-24 15:21:54,548 - INFO - rxn_mapper process... -2024-06-24 15:21:58,273 - INFO - Starting mapping of 50016 reactions in batches of 50016. -2024-06-24 15:21:58,273 - INFO - Processing batch from index 0 to 50016. -2024-06-24 15:38:05,849 - INFO - Successfully processed Internal Batch from 0 to 50016 -2024-06-24 15:38:05,849 - INFO - Completed mapping all reactions. -2024-06-24 15:38:05,849 - INFO - graphormer process... -2024-06-24 15:38:08,803 - INFO - Starting mapping of 50016 reactions in batches of 50016. -2024-06-24 15:38:08,805 - INFO - Processing batch from index 0 to 50016. -2024-06-24 15:38:37,011 - ERROR - Graphormer mapping failed for reaction 'CC(=O)CC(=O)N[C@@H](CC(=O)O)C(=O)O>>CC(=O)CC(=O)N[C@H]1CC(=O)OC1=O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:38:37,264 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1cccc([C@@H](C)C(=O)O)c1>>COC(=O)[C@H](C)c1cccc(C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:39:09,157 - ERROR - Graphormer mapping failed for reaction 'CCO.Cc1ccc(C(=O)O)cc1Br>>CCOC(=O)c1ccc(C)c(Br)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:39:31,892 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1c(N)cncc1C(=O)O>>COC(=O)c1cncc(N)c1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:39:36,197 - ERROR - Graphormer mapping failed for reaction 'O=C(O)c1cc2ccoc2nc1C(=O)O>>O=C1OC(=O)c2nc3occc3cc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:40:24,846 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ccc(Cl)cc1Oc1cccc(C(F)(F)F)c1>>COC(=O)c1ccc(Cl)cc1Oc1cccc(C(F)(F)F)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:40:25,977 - ERROR - Graphormer mapping failed for reaction 'C#CC(O)c1ccc2ccccc2c1.O=C(O)C1CC1>>C#CC(OC(=O)C1CC1)c1ccc2ccccc2c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:40:50,900 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ncccc1Br>>COC(=O)c1ncccc1Br.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:41:37,960 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)[C@H](O)Cc1ccc(O)c(Br)c1>>COC(=O)[C@H](O)Cc1ccc(O)c(Br)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:42:40,209 - ERROR - Graphormer mapping failed for reaction 'CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.OCCO>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCCO.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:42:49,490 - ERROR - Graphormer mapping failed for reaction 'Nc1ccc(CC(C(=O)O)c2cn(C3CCCCC3)cn2)cn1.OCCO>>Nc1ccc(CC(C(=O)OCCO)c2cn(C3CCCCC3)cn2)cn1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:42:53,274 - ERROR - Graphormer mapping failed for reaction 'C#CCO.Cc1ccc(O)cc1C>>C#CCOc1ccc(C)c(C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:43:38,943 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)C1Oc2ccccc2C2(CC2)c2ccccc2O1>>COC(=O)C1Oc2ccccc2C2(CC2)c2ccccc2O1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:43:39,142 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)C=Cc1cccc(Br)c1>>CCOC(=O)C=Cc1cccc(Br)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:43:41,485 - ERROR - Graphormer mapping failed for reaction 'C#CCOCCCCCCCCCCO.O=C(O)C1CC1>>C#CCOCCCCCCCCCCOC(=O)C1CC1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:43:45,870 - ERROR - Graphormer mapping failed for reaction 'O=C(O)CC[C@@H](C(=O)OCc1ccccc1)n1c2ccccc2c2ccccc21.OCCO>>O=C(CC[C@@H](C(=O)OCc1ccccc1)n1c2ccccc2c2ccccc21)OCCO.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:43:45,945 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)Cc1cc(OCc2ccccc2)cc(C(F)(F)F)c1>>CCOC(=O)Cc1cc(OCc2ccccc2)cc(C(F)(F)F)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:43:58,671 - ERROR - Graphormer mapping failed for reaction 'CCO.[Cl-].CC1=[N+](CCCCCC(=O)O)c2ccc(Br)cc2C1(C)C>>O.CCOC(=O)CCCCC[N+]1=C(C)C(C)(C)c2cc(Br)ccc21.[Cl-]': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:44:04,531 - ERROR - Graphormer mapping failed for reaction 'CC1(CO)CC1.Cc1ccc(O)cn1>>Cc1ccc(OCC2(C)CC2)cn1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:44:08,762 - ERROR - Graphormer mapping failed for reaction 'COC(=O)c1ccc(O)c(C)c1.OCC(F)F>>COC(=O)c1ccc(OCC(F)F)c(C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:44:22,873 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ccc(O)cn1>>COC(=O)c1ccc(O)cn1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:44:38,259 - ERROR - Graphormer mapping failed for reaction 'CC(C)O.O=C(O)Cc1cc(C(F)(F)F)ccc1I>>CC(C)OC(=O)Cc1cc(C(F)(F)F)ccc1I.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:45:15,975 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1ccc(S(=O)(=O)NCC(=O)O)cc1>>COC(=O)CNS(=O)(=O)c1ccc(C)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:45:33,183 - ERROR - Graphormer mapping failed for reaction 'C[C@H](N)C(=O)O.OC1CCCC1>>C[C@H](N)C(=O)OC1CCCC1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:45:44,770 - ERROR - Graphormer mapping failed for reaction 'CCC(CC)(c1ccc(O)c(C)c1)c1ccc(C#CC(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c1.O=C1CCC[C@@H](CO)O1>>CCC(CC)(c1ccc(C#CC(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(OC[C@@H]2CCCC(=O)O2)c(C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:46:00,069 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1cccc(Br)c1F>>COC(=O)c1cccc(Br)c1F.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:47:10,332 - ERROR - Graphormer mapping failed for reaction 'CCOC(=O)Cn1nnc(-c2cc(O)no2)n1.OCC1(COc2cc(F)ccc2Br)CC1>>CCOC(=O)Cn1nnc(-c2cc(OCC3(COc4cc(F)ccc4Br)CC3)no2)n1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:47:30,189 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)C1Cc2cscc2C1>>COC(=O)C1Cc2cscc2C1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:48:25,247 - ERROR - Graphormer mapping failed for reaction 'CCO.COc1c(C(C)(C)CC(=O)C(=O)O)ccc(Cl)c1F>>CCOC(=O)C(=O)CC(C)(C)c1ccc(Cl)c(F)c1OC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:48:30,965 - ERROR - Graphormer mapping failed for reaction 'CO.Nc1nc(CC(=O)O)cs1>>COC(=O)Cc1csc(N)n1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:50:26,423 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1cc2cc(C(=O)O)ccc2s1>>COC(=O)c1ccc2sc(C)cc2c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:50:31,249 - ERROR - Graphormer mapping failed for reaction 'CC1(c2ccccc2)OC(C(=O)O)=CC1=O.CO>>COC(=O)C1=CC(=O)C(C)(c2ccccc2)O1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:51:01,377 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ccc(O)c(C(F)(F)F)c1>>COC(=O)c1ccc(O)c(C(F)(F)F)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:52:45,675 - ERROR - Graphormer mapping failed for reaction 'CCO.COc1c(F)c(F)cc(C(=O)O)c1F>>CCOC(=O)c1cc(F)c(F)c(OC)c1F.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:52:52,518 - ERROR - Graphormer mapping failed for reaction 'CN(C)C1CCN(c2ccc(-n3ccc(O)cc3=O)cn2)C1.OCc1ccc(F)cn1>>CN(C)C1CCN(c2ccc(-n3ccc(OCc4ccc(F)cn4)cc3=O)cn2)C1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:53:11,372 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)C1(c2ccccc2)CCNCC1>>CCOC(=O)C1(c2ccccc2)CCNCC1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:53:32,896 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)c1cc(Cl)ccc1Br>>CCOC(=O)c1cc(Cl)ccc1Br.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:54:38,648 - ERROR - Graphormer mapping failed for reaction 'CO.O=C1Nc2ccc(C(=O)O)cc2C1=Cc1ccnc2ccccc12>>COC(=O)c1ccc2c(c1)C(=Cc1ccnc3ccccc13)C(=O)N2.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:54:59,867 - ERROR - Graphormer mapping failed for reaction 'CC1(C2CCCC2)Cc2cc(OCCCC(=O)O)c(Cl)c(Cl)c2C1=O.CCO>>CCOC(=O)CCCOc1cc2c(c(Cl)c1Cl)C(=O)C(C)(C1CCCC1)C2.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:55:19,649 - ERROR - Graphormer mapping failed for reaction 'CC(C)=CCC/C(C)=C/CO.CNC(=O)O[C@@H]1OC=C(C(=O)O)[C@H]2C[C@@H]3O[C@]3(C)[C@@H]21>>CNC(=O)O[C@@H]1OC=C(C(=O)OC/C=C(\C)CCC=C(C)C)[C@H]2C[C@@H]3O[C@]3(C)[C@@H]21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:55:45,973 - ERROR - Graphormer mapping failed for reaction 'CCO.COc1ccc(C(=O)O)cc1N>>CCOC(=O)c1ccc(OC)c(N)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:56:16,107 - ERROR - Graphormer mapping failed for reaction 'CCO.Cc1ccc(F)c(C(=O)O)c1>>CCOC(=O)c1cc(C)ccc1F.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:56:17,862 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)c1cc(F)cc(Br)c1>>CCOC(=O)c1cc(F)cc(Br)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:57:04,238 - ERROR - Graphormer mapping failed for reaction 'Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1cc(Br)c(Cl)s1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cc(Br)c(Cl)s4)cc3=O)cc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:57:05,714 - ERROR - Graphormer mapping failed for reaction 'CC(=O)O.O=C(O)c1cc(O)cc(OCc2ccccc2)c1>>CC(=O)Oc1cc(OCc2ccccc2)cc(C(=O)O)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:57:12,542 - ERROR - Graphormer mapping failed for reaction 'O=[N+]([O-])c1ccc(O)nc1.OCc1cccc(F)c1>>O=[N+]([O-])c1ccc(OCc2cccc(F)c2)nc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:57:15,087 - ERROR - Graphormer mapping failed for reaction 'CCC(N)CCCCCCCCC(C)(C)C(=O)O.CO>>CCC(N)CCCCCCCCC(C)(C)C(=O)OC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:57:19,426 - ERROR - Graphormer mapping failed for reaction 'CO.Nc1ccc([N+](=O)[O-])cc1C(=O)O>>COC(=O)c1cc([N+](=O)[O-])ccc1N.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:57:19,611 - ERROR - Graphormer mapping failed for reaction 'COC(=O)c1sc(-n2cnc3cc(Cl)c(Cl)cc32)cc1O.OCc1cccs1>>COC(=O)c1sc(-n2cnc3cc(Cl)c(Cl)cc32)cc1OCc1cccs1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:58:02,439 - ERROR - Graphormer mapping failed for reaction 'CCO.Cc1cc(Cl)ccc1Cn1nc(C(=O)O)c2ccccc21>>CCOC(=O)c1nn(Cc2ccc(Cl)cc2C)c2ccccc12.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:58:14,894 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CCCc1ccc(C(=O)C=Cc2ccccc2)cc1>>COC(=O)CCCc1ccc(C(=O)C=Cc2ccccc2)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:58:23,638 - ERROR - Graphormer mapping failed for reaction 'COC(=O)c1cc(O)ccc1[N+](=O)[O-].OCc1cccs1>>COC(=O)c1cc(OCc2cccs2)ccc1[N+](=O)[O-].O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:58:40,485 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1ccc2c(c1)Cc1cc(C(=O)O)ccc1O2>>COC(=O)c1ccc2c(c1)Cc1cc(C)ccc1O2.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:59:24,893 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)Cc1ccccc1Oc1ccccc1>>COC(=O)Cc1ccccc1Oc1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 15:59:47,015 - ERROR - Graphormer mapping failed for reaction 'CCCc1ccc(C(CC(=O)O)CC(=O)O)cc1>>CCCc1ccc(C2CC(=O)OC(=O)C2)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:00:10,771 - ERROR - Graphormer mapping failed for reaction 'C#CCO.CC(O)C(=O)O>>C#CCOC(=O)C(C)O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:00:13,512 - ERROR - Graphormer mapping failed for reaction 'O=C(O)c1cc2cc(OC(F)F)ccc2nc1C(=O)O>>O=C1OC(=O)c2nc3ccc(OC(F)F)cc3cc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:01:04,508 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C(=O)O)c1ccc(OCc2ccccc2)cc1.CCO>>CCOC(=O)C(C)(C)c1ccc(OCc2ccccc2)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:01:26,200 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C)CO.CCOC(=O)Cn1nc(C(=O)OCC)cc1O>>CCOC(=O)Cn1nc(C(=O)OCC)cc1OCC(C)(C)C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:02:03,027 - ERROR - Graphormer mapping failed for reaction 'CCCC(C)(OC)C(=O)O.CO>>CCCC(C)(OC)C(=O)OC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:03:06,201 - ERROR - Graphormer mapping failed for reaction 'CO.COc1ccccc1Sc1ccccc1C(=O)O>>COC(=O)c1ccccc1Sc1ccccc1OC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:03:14,401 - ERROR - Graphormer mapping failed for reaction 'CN1CCN(CCO)CC1.Cc1c(O)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12>>Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:03:23,636 - ERROR - Graphormer mapping failed for reaction 'CC(=O)CC(=O)N[C@@H](CC(=O)O)C(=O)O>>CC(=O)CC(=O)N[C@H]1CC(=O)OC1=O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:04:17,612 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)c1ccc(Br)c(O)c1>>CCOC(=O)c1ccc(Br)c(O)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:04:18,327 - ERROR - Graphormer mapping failed for reaction 'CC(=O)SCC(C)C(=O)O.O=C(O)CO>>CC(=O)SCC(C)C(=O)OC(=O)CO.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:04:24,001 - ERROR - Graphormer mapping failed for reaction 'CC(C)O.Cc1nnsc1C(=O)O>>Cc1nnsc1C(=O)OC(C)C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:04:56,207 - ERROR - Graphormer mapping failed for reaction 'CC(C)(CO)C(=O)O.CO>>COC(=O)C(C)(C)CO.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:05:58,859 - ERROR - Graphormer mapping failed for reaction 'CC(=O)SCCC(=O)O.O=C(O)CO>>CC(=O)SCCC(=O)OC(=O)CO.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:06:21,198 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1ccc(I)c(C(=O)O)c1>>COC(=O)c1cc(C)ccc1I.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:06:37,028 - ERROR - Graphormer mapping failed for reaction 'CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2CCCc2ccc(C(=O)O)s2)cc1.OCCO>>CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2CCCc2ccc(C(=O)OCCO)s2)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:06:37,339 - ERROR - Graphormer mapping failed for reaction 'CC1(C)CC(Nc2nccc(-c3cc4ccc(O)cc4s3)n2)CC(C)(C)N1.CCO>>CCOc1ccc2cc(-c3ccnc(NC4CC(C)(C)NC(C)(C)C4)n3)sc2c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:06:46,654 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1ccc(-c2oncc2CCC(=O)O)cc1>>COC(=O)CCc1cnoc1-c1ccc(C)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:07:33,088 - ERROR - Graphormer mapping failed for reaction 'O=C(O)c1cc(O)c2ccccc2c1O.OCCBr>>O=C(O)c1cc(OCCBr)c2ccccc2c1O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:08:17,152 - ERROR - Graphormer mapping failed for reaction 'Cn1c(CCCO)nc2ccccc21.Cn1cc(O)c(=O)c(-c2ccnn2-c2ccccc2)n1>>Cn1cc(OCCCc2nc3ccccc3n2C)c(=O)c(-c2ccnn2-c2ccccc2)n1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:08:17,376 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ccc(Cl)cc1>>COC(=O)c1ccc(Cl)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:09:14,261 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)C(F)(F)CNc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>CCOC(=O)C(F)(F)CNc1c([N+](=O)[O-])cccc1[N+](=O)[O-].O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:09:26,228 - ERROR - Graphormer mapping failed for reaction 'O=C(O)c1ccc(C(F)(F)F)cc1C(=O)O>>O=C1OC(=O)c2cc(C(F)(F)F)ccc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:10:01,185 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C)O.O=C(O)c1ccc(CBr)cc1>>CC(C)(C)OC(=O)c1ccc(CBr)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:10:14,169 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CCc1conc1-c1ccc(Cl)c(Cl)c1>>COC(=O)CCc1conc1-c1ccc(Cl)c(Cl)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:10:32,054 - ERROR - Graphormer mapping failed for reaction 'Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1ccsc1Cl>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccsc4Cl)cc3=O)cc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:11:03,232 - ERROR - Graphormer mapping failed for reaction 'CC(C)C[C@H](CC(=O)O)C(=O)O>>CC(C)C[C@@H]1CC(=O)OC1=O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:11:10,535 - ERROR - Graphormer mapping failed for reaction 'O=C(O)Cc1cc(OCc2ccccc2)ccc1C(=O)O>>O=C1Cc2cc(OCc3ccccc3)ccc2C(=O)O1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:11:22,808 - ERROR - Graphormer mapping failed for reaction 'CC(C)N1CCC(O)C1.CCOC(=O)c1cc2cc(O)ccc2[nH]1>>CCOC(=O)c1cc2cc(OC3CCN(C(C)C)C3)ccc2[nH]1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:11:57,019 - ERROR - Graphormer mapping failed for reaction 'CCO.COc1cc(CC(=O)O)ccc1OC(F)F>>CCOC(=O)Cc1ccc(OC(F)F)c(OC)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:12:36,471 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1cc(I)ccc1O>>COC(=O)c1cc(I)ccc1O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:12:46,472 - ERROR - Graphormer mapping failed for reaction 'C#CCc1c(F)c(F)c(CO)c(F)c1F.CC(C#N)=C[C@@H]1[C@@H](C(=O)O)C1(C)C>>C#CCc1c(F)c(F)c(COC(=O)[C@@H]2[C@@H](C=C(C)C#N)C2(C)C)c(F)c1F.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:12:57,827 - ERROR - Graphormer mapping failed for reaction 'CC1(C)CCC=C1c1cc(C(=O)O)ccc1-c1cc(O)ccc1F.CO>>COC(=O)c1ccc(-c2cc(O)ccc2F)c(C2=CCCC2(C)C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:13:20,663 - ERROR - Graphormer mapping failed for reaction 'COC(=O)[C@@H](O)Cc1ccccc1.COc1c2ccccc2c(-c2cc(Br)c(O)c(Br)c2)c2c1sc1ccccc12>>COC(=O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(OC)c3sc4ccccc4c23)cc1Br.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:13:24,309 - ERROR - Graphormer mapping failed for reaction 'CCO.COc1c(F)cccc1C1(CC(=O)C(=O)O)CC1>>CCOC(=O)C(=O)CC1(c2cccc(F)c2OC)CC1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:13:24,438 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CCC(c1cccc(Cl)c1)C1(Br)C(=O)Nc2cc(Cl)ccc21>>COC(=O)CCC(c1cccc(Cl)c1)C1(Br)C(=O)Nc2cc(Cl)ccc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:13:53,286 - ERROR - Graphormer mapping failed for reaction 'CO.COc1ccc(CC(=O)O)c(Oc2ccccc2)c1>>COC(=O)Cc1ccc(OC)cc1Oc1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:15:30,681 - ERROR - Graphormer mapping failed for reaction 'C=C(C)C(=O)O.O=C(O)c1ccc(-c2ccc(OCCCCCCO)cc2)cc1>>C=C(C)C(=O)OCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:15:32,834 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CC(c1ccc(O)cc1)C1CC1>>COC(=O)CC(c1ccc(O)cc1)C1CC1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:15:44,094 - ERROR - Graphormer mapping failed for reaction 'COC(=O)c1ccc(F)c(-c2c(F)cc(O)cc2F)n1.OC1CCCOC1>>COC(=O)c1ccc(F)c(-c2c(F)cc(OC3CCCOC3)cc2F)n1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:15:48,918 - ERROR - Graphormer mapping failed for reaction 'CCOC(=O)c1c(O)c(O)c(C(=O)OCC)n1-c1ccc(F)cc1.OCCOCc1ccccc1>>CCOC(=O)c1c(O)c(OCCOCc2ccccc2)c(C(=O)OCC)n1-c1ccc(F)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:16:17,407 - ERROR - Graphormer mapping failed for reaction 'C=CC(=O)O.CCCCO>>C=CC(=O)OCCCC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:17:11,863 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)Cc1ccccc1Cl>>COC(=O)Cc1ccccc1Cl.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:18:00,337 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)Cc1ccc2c(c1)OCO2>>COC(=O)Cc1ccc2c(c1)OCO2.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:19:36,969 - ERROR - Graphormer mapping failed for reaction 'CCCCC(C)C(=O)O.OCC1CC1>>CCCCC(C)C(=O)OCC1CC1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:19:45,021 - ERROR - Graphormer mapping failed for reaction 'O=C(O)CS.OCCc1ccccc1>>O=C(CS)OCCc1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:20:06,827 - ERROR - Graphormer mapping failed for reaction 'CCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O>>CCCCCCCCCCCC(=O)N[C@H]1CCC(=O)OC1=O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:20:45,624 - ERROR - Graphormer mapping failed for reaction 'CC(C)CO.COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2O)cc1>>COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)ccc2OCC(C)C)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:20:55,065 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)C=Cc1ccc(C2CCCCC2)c(Cl)c1>>CCOC(=O)C=Cc1ccc(C2CCCCC2)c(Cl)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:21:16,794 - ERROR - Graphormer mapping failed for reaction 'O=C(O)Cn1nnnc1-c1cccc(C(F)(F)F)c1.OCCO>>O=C(Cn1nnnc1-c1cccc(C(F)(F)F)c1)OCCO.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:21:27,847 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)c1ccc(O)cc1>>CCOc1ccc(C(=O)O)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:21:37,035 - ERROR - Graphormer mapping failed for reaction 'CO.Nc1ccc(-c2ccc(C(=O)O)cc2)cn1>>COC(=O)c1ccc(-c2ccc(N)nc2)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:21:48,710 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2cc(-c3cn(S(=O)(=O)c4ccccc4)c4ncc(O)cc34)cc(Cl)n2)CC1.CCO>>CCOc1cnc2c(c1)c(-c1cc(Cl)nc(N[C@@H]3CC[C@@H](NC(=O)OC(C)(C)C)CC3)c1)cn2S(=O)(=O)c1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:22:39,522 - ERROR - Graphormer mapping failed for reaction 'C=CCc1c(F)c(F)c(CO)c(F)c1F.CC(C#N)=C[C@@H]1[C@@H](C(=O)O)C1(C)C>>C=CCc1c(F)c(F)c(COC(=O)[C@@H]2[C@@H](C=C(C)C#N)C2(C)C)c(F)c1F.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:22:49,915 - ERROR - Graphormer mapping failed for reaction 'COc1cc(-c2cc3ncccc3c(O)n2)cc(OC)c1OC.COc1ccc([C@H](C)N2C[C@H]([C@H](C)O)CC2=O)cc1>>COc1ccc([C@H](C)N2C[C@H]([C@@H](C)Oc3nc(-c4cc(OC)c(OC)c(OC)c4)cc4ncccc34)CC2=O)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:23:43,703 - ERROR - Graphormer mapping failed for reaction 'CCO.Nc1ccc(F)cc1C(=O)O>>CCOC(=O)c1cc(F)ccc1N.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:24:45,736 - ERROR - Graphormer mapping failed for reaction 'Cc1onc(-c2ccccc2)c1CO.Oc1cnc2ccccc2n1>>Cc1onc(-c2ccccc2)c1COc1cnc2ccccc2n1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:25:09,347 - ERROR - Graphormer mapping failed for reaction 'CO.COc1ccccc1Oc1c(NS(=O)(=O)C=Cc2ccc(C(=O)O)cc2)nc(-c2ncccn2)nc1OC>>COC(=O)c1ccc(C=CS(=O)(=O)Nc2nc(-c3ncccn3)nc(OC)c2Oc2ccccc2OC)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:25:25,573 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C)c1cc(C(=O)O)cc(I)c1O.CO>>COC(=O)c1cc(I)c(O)c(C(C)(C)C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:25:27,207 - ERROR - Graphormer mapping failed for reaction 'CCc1nc2ccc(-n3ccc(O)cc3=O)cc2n1C.OCc1ccc(C(F)(F)F)s1>>CCc1nc2ccc(-n3ccc(OCc4ccc(C(F)(F)F)s4)cc3=O)cc2n1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:25:39,352 - ERROR - Graphormer mapping failed for reaction 'O=C(O)CCCCCSCCCCCCCCO>>O=C1CCCCCSCCCCCCCCO1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:26:50,561 - ERROR - Graphormer mapping failed for reaction 'Cc1c(OCCCNS(C)(=O)=O)cn2ncnc(O)c12.Cc1cc2c(F)c(O)ccc2[nH]1>>Cc1cc2c(F)c(Oc3ncnn4cc(OCCCNS(C)(=O)=O)c(C)c34)ccc2[nH]1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:27:52,423 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1cccc2c1OCC2>>COC(=O)c1cccc2c1OCC2.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:28:19,814 - ERROR - Graphormer mapping failed for reaction 'Cc1nc2ccc(-n3ccc(O)cc3=O)cc2n1C.OCc1csc(C(F)(F)F)c1>>Cc1nc2ccc(-n3ccc(OCc4csc(C(F)(F)F)c4)cc3=O)cc2n1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:29:23,500 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C)OCCO.Oc1ccc2[nH]ccc2c1>>CC(C)(C)OCCOc1ccc2[nH]ccc2c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:29:39,784 - ERROR - Graphormer mapping failed for reaction 'CO.CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1>>COC(=O)C(CC1CCCC1)c1ccc(S(C)(=O)=O)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:29:55,824 - ERROR - Graphormer mapping failed for reaction 'O=c1c(O)cn(-c2ccc(C3CCOCC3)cc2F)nc1-c1ccnn1-c1ccccc1.OCCF>>O=c1c(OCCF)cn(-c2ccc(C3CCOCC3)cc2F)nc1-c1ccnn1-c1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:30:10,907 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1cc(CCCC2CN(Cc3ccc(C(C)(C)C)cc3)C(=O)N2C)ccc1OC(C)(C)C(=O)O>>COC(=O)C(C)(C)Oc1ccc(CCCC2CN(Cc3ccc(C(C)(C)C)cc3)C(=O)N2C)cc1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:30:38,881 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ccc(Br)cc1[N+](=O)[O-]>>COC(=O)c1ccc(Br)cc1[N+](=O)[O-].O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:30:41,403 - ERROR - Graphormer mapping failed for reaction 'C=CCO.CC(C(=O)O)c1ccc2c(c1)SCC1CCCCC1C2=O>>C=CCOC(=O)C(C)c1ccc2c(c1)SCC1CCCCC1C2=O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:31:37,806 - ERROR - Graphormer mapping failed for reaction 'O=C(O)[C@@H]1CCCC[C@H]1C(=O)O>>O=C1OC(=O)[C@@H]2CCCC[C@@H]12.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:31:39,419 - ERROR - Graphormer mapping failed for reaction 'CC(C(=O)O)C(C)C(=O)O>>CC1C(=O)OC(=O)C1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:32:17,829 - ERROR - Graphormer mapping failed for reaction 'CCO.Cc1cc2c(s1)C(C(=O)O)CC2>>CCOC(=O)C1CCc2cc(C)sc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:32:27,578 - ERROR - Graphormer mapping failed for reaction 'Cc1c2cc(-n3ccc(O)cc3=O)ccc2nn1C.OCc1cccc(Cl)c1>>Cc1c2cc(-n3ccc(OCc4cccc(Cl)c4)cc3=O)ccc2nn1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:32:30,249 - ERROR - Graphormer mapping failed for reaction 'O=C(O)CC1(CC(=O)O)CCCCC1>>O=C1CC2(CCCCC2)CC(=O)O1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:32:41,949 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)Cc1c(F)cccc1Cl>>CCOC(=O)Cc1c(F)cccc1Cl.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:32:45,242 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CC(c1cccc(O)c1)C1CC1>>COC(=O)CC(c1cccc(O)c1)C1CC1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:33:15,942 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1c2nc3ccccc3c-2[nH]c2ccccc12>>COC(=O)c1c2nc3ccccc3c-2[nH]c2ccccc12.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:33:31,050 - ERROR - Graphormer mapping failed for reaction 'CO.Nc1ccc(C(=O)c2ccccc2C(=O)O)cc1[N+](=O)[O-]>>COC(=O)c1ccccc1C(=O)c1ccc(N)c([N+](=O)[O-])c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:33:51,116 - ERROR - Graphormer mapping failed for reaction 'CCC#CCCO.CCCC(=O)O>>CCC#CCCOC(=O)CCC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:34:39,256 - ERROR - Graphormer mapping failed for reaction 'O=C(O)[C@@H]1CCCN1.O=[N+]([O-])c1ccc(CO)cc1>>O=C(OCc1ccc([N+](=O)[O-])cc1)[C@@H]1CCCN1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:35:20,130 - ERROR - Graphormer mapping failed for reaction 'C=C(C)C(=O)O.OC1Cc2cccc3cccc1c23>>C=C(C)C(=O)OC1Cc2cccc3cccc1c23.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:35:24,603 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)Cn1c(=O)[nH]c(=O)c2ccc(Cl)cc21>>CCOC(=O)Cn1c(=O)[nH]c(=O)c2ccc(Cl)cc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:35:24,906 - ERROR - Graphormer mapping failed for reaction 'CO.Nc1ccc(C(=O)O)c(O)c1>>COC(=O)c1ccc(N)cc1O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:35:47,576 - ERROR - Graphormer mapping failed for reaction 'O=C(O)CCS.OCCCc1ccccc1>>O=C(CCS)OCCCc1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:36:01,912 - ERROR - Graphormer mapping failed for reaction 'Cc1c2cc(-n3ccc(O)cc3=O)ccc2nn1C.OCc1nc(C(F)(F)F)cs1>>Cc1c2cc(-n3ccc(OCc4nc(C(F)(F)F)cs4)cc3=O)ccc2nn1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:37:02,792 - ERROR - Graphormer mapping failed for reaction 'COc1ccccc1CCO.N#Cc1cccc(-n2nc(C(F)(F)F)cc2O)c1>>COc1ccccc1CCOc1cc(C(F)(F)F)nn1-c1cccc(C#N)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:38:15,140 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CC1NCCc2ccccc21>>COC(=O)CC1NCCc2ccccc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:38:20,323 - ERROR - Graphormer mapping failed for reaction 'O=C(O)Cc1ccc([N+](=O)[O-])cc1C(=O)O>>O=C1Cc2ccc([N+](=O)[O-])cc2C(=O)O1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:38:41,336 - ERROR - Graphormer mapping failed for reaction 'O=C(O)CCCBr.OCC1c2ccccc2-c2ccccc21>>O=C(CCCBr)OCC1c2ccccc2-c2ccccc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:38:45,823 - ERROR - Graphormer mapping failed for reaction 'CC(C)c1noc(N2CCC(CCCO)CC2)n1.CCOC(=O)c1ccc(O)nc1C>>CCOC(=O)c1ccc(OCCCC2CCN(c3nc(C(C)C)no3)CC2)nc1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:39:13,300 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)Cc1ccccc1[N+](=O)[O-]>>COC(=O)Cc1ccccc1[N+](=O)[O-].O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:39:24,673 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1cc(F)cnc1Cl>>COC(=O)c1cc(F)cnc1Cl.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:39:59,711 - ERROR - Graphormer mapping failed for reaction 'CCO.Cc1cc(C(=O)O)ccc1F>>CCOC(=O)c1ccc(F)c(C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:40:00,053 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C)OC(=O)NCC(=O)c1ccc(OCC(=O)O)cc1.CC(C)O>>CC(C)OC(=O)COc1ccc(C(=O)CNC(=O)OC(C)(C)C)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:40:26,583 - ERROR - Graphormer mapping failed for reaction 'COC(=O)[C@H](O)Cc1ccccc1.Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br>>COC(=O)[C@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:40:27,589 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1c(O)cccc1F>>COC(=O)c1c(O)cccc1F.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:40:43,319 - ERROR - Graphormer mapping failed for reaction 'CCCCCCCCC#CCC#CCC#CCS(=O)(=O)CC(=O)O.CO>>CCCCCCCCC#CCC#CCC#CCS(=O)(=O)CC(=O)OC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:41:20,184 - ERROR - Graphormer mapping failed for reaction 'CO.Cc1n[nH]c2cc(C(=O)O)ccc12>>COC(=O)c1ccc2c(C)n[nH]c2c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:41:37,469 - ERROR - Graphormer mapping failed for reaction 'CCCCOc1cc(C(=O)O)ccc1[N+](=O)[O-].CO>>CCCCOc1cc(C(=O)OC)ccc1[N+](=O)[O-].O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:42:08,064 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1cccc(Cc2ccccc2)c1O>>COC(=O)c1cccc(Cc2ccccc2)c1O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:42:36,874 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)c1ccnc(Cl)c1>>CCOC(=O)c1ccnc(Cl)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:43:11,368 - ERROR - Graphormer mapping failed for reaction 'CO.COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)[C@H]([C@@H](C)O)[C@H]2C(=O)O)cc1>>COC(=O)[C@@H]1[C@@H]([C@@H](C)O)C(=O)N1C(Cc1ccc(OC)cc1)Cc1ccc(OC)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:43:27,370 - ERROR - Graphormer mapping failed for reaction 'CCCn1c(=O)c2nc(C(CC)c3ccc(NCC(=O)O)cc3)[nH]c2n(CCC)c1=O.CO>>CCCn1c(=O)c2nc(C(CC)c3ccc(NCC(=O)OC)cc3)[nH]c2n(CCC)c1=O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:43:33,265 - ERROR - Graphormer mapping failed for reaction 'CO.COc1ccc(C(=O)O)c2ccoc12>>COC(=O)c1ccc(OC)c2occc12.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:44:42,582 - ERROR - Graphormer mapping failed for reaction 'CCO.COc1ccc(CC(=O)O)cc1Br>>CCOC(=O)Cc1ccc(OC)c(Br)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:44:47,883 - ERROR - Graphormer mapping failed for reaction 'CCCCCCCCO.NCC(=O)CCC(=O)O>>CCCCCCCCOC(=O)CCC(=O)CN.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:45:27,878 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ccc(Cl)c(Cl)c1Sc1ccccc1>>COC(=O)c1ccc(Cl)c(Cl)c1Sc1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:46:07,318 - ERROR - Graphormer mapping failed for reaction 'C#CCO.CC(C)(Br)C(=O)O>>C#CCOC(=O)C(C)(C)Br.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:46:21,306 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1cnc(O)c(Br)c1>>COC(=O)c1cnc(O)c(Br)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:46:31,566 - ERROR - Graphormer mapping failed for reaction 'CC(=O)c1ccc(O)cc1O.COCCO>>COCCOc1ccc(C(C)=O)c(O)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:46:35,859 - ERROR - Graphormer mapping failed for reaction 'CC(C)(C)OC(=O)C(C)(C)Sc1ccc(C(=O)O)cc1.CCCc1nn(Cc2ccc(C(F)(F)F)cc2)cc1CO>>CCCc1nn(Cc2ccc(C(F)(F)F)cc2)cc1COC(=O)c1ccc(SC(C)(C)C(=O)OC(C)(C)C)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:47:39,808 - ERROR - Graphormer mapping failed for reaction 'CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(O)c(C)c2)cc1C)CC.O=C1CCC[C@@H](CO)O1>>CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(OC[C@@H]3CCCC(=O)O3)c(C)c2)cc1C)CC.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:48:03,943 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)Cc1ccc(F)cc1I>>COC(=O)Cc1ccc(F)cc1I.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:48:19,421 - ERROR - Graphormer mapping failed for reaction 'O=C(O)c1cnc(Cl)cn1.OCCOC1CCCCO1>>O=C(OCCOC1CCCCO1)c1cnc(Cl)cn1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:48:32,546 - ERROR - Graphormer mapping failed for reaction 'CO.N[C@@H](CC(=O)O)c1ccccc1>>COC(=O)C[C@H](N)c1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:49:11,098 - ERROR - Graphormer mapping failed for reaction 'CO.COc1ccc(C(=O)O)cc1C>>COC(=O)c1ccc(OC)c(C)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:49:22,609 - ERROR - Graphormer mapping failed for reaction 'CCO.Nc1ccc(Br)cc1C(=O)O>>CCOC(=O)c1cc(Br)ccc1N.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:49:43,064 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CCCc1ccc(I)cc1>>COC(=O)CCCc1ccc(I)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:50:07,739 - ERROR - Graphormer mapping failed for reaction 'CCOC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O>>CCOC(=O)CN(CCN(CCN1CC(=O)OC(=O)C1)CC(=O)O)CC(=O)O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:50:21,831 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)CCc1cnoc1-c1ccc(Cl)c(Cl)c1>>COC(=O)CCc1cnoc1-c1ccc(Cl)c(Cl)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:50:30,039 - ERROR - Graphormer mapping failed for reaction 'CC(=O)Oc1cccc(O)c1.OC1CCC1>>CC(=O)Oc1cccc(OC2CCC2)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:51:35,552 - ERROR - Graphormer mapping failed for reaction 'CCC(C)(C)O.O=C(O)c1cc(Cl)c(Cl)nc1Cl>>CCC(C)(C)OC(=O)c1cc(Cl)c(Cl)nc1Cl.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:51:50,082 - ERROR - Graphormer mapping failed for reaction 'CCO.Nc1ccc(C(=O)O)cc1[N+](=O)[O-]>>CCOC(=O)c1ccc(N)c([N+](=O)[O-])c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:52:24,231 - ERROR - Graphormer mapping failed for reaction 'CC(=O)c1ccc(O)cc1O.OC1CCOCC1>>CC(=O)c1ccc(OC2CCOCC2)cc1O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:52:30,403 - ERROR - Graphormer mapping failed for reaction 'O=C(O)c1cc2ccccc2nc1C(=O)O>>O=C1OC(=O)c2nc3ccccc3cc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:52:32,126 - ERROR - Graphormer mapping failed for reaction 'CCO.O=C(O)CCc1cc2ccccc2c(-c2ccccc2)n1>>CCOC(=O)CCc1cc2ccccc2c(-c2ccccc2)n1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:53:09,099 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)C=Cc1cccc(Br)c1>>COC(=O)/C=C/c1cccc(Br)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:53:37,565 - ERROR - Graphormer mapping failed for reaction 'CCO.COc1ccc2cc(C(C)C(=O)O)ccc2c1>>CCOC(=O)C(C)c1ccc2cc(OC)ccc2c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:54:09,630 - ERROR - Graphormer mapping failed for reaction 'CCO.Cc1ccc(C(=O)O)cc1I>>CCOC(=O)c1ccc(C)c(I)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:54:27,181 - ERROR - Graphormer mapping failed for reaction 'CO.COc1cc(F)c(C(=O)O)c(F)c1>>COC(=O)c1c(F)cc(OC)cc1F.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:55:14,030 - ERROR - Graphormer mapping failed for reaction 'CO.NC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>COC(=O)[C@H](CN)NC(=O)OCc1ccccc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:55:42,639 - ERROR - Graphormer mapping failed for reaction 'Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1csc(Br)c1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4csc(Br)c4)cc3=O)cc21.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:55:53,435 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)Cc1ccc(F)cc1>>COC(=O)Cc1ccc(F)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:56:26,275 - ERROR - Graphormer mapping failed for reaction 'CC(C)O.O=C(O)c1ccc(I)cc1>>CC(C)OC(=O)c1ccc(I)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:56:49,698 - ERROR - Graphormer mapping failed for reaction 'CCc1nc2ccc(-n3ccc(O)cc3=O)cc2n1C.OCc1ccc(Cl)c(F)c1>>CCc1nc2ccc(-n3ccc(OCc4ccc(Cl)c(F)c4)cc3=O)cc2n1C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:57:40,582 - ERROR - Graphormer mapping failed for reaction 'COC(=O)[C@@H](O)Cc1ccccc1.Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br>>COC(=O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:58:20,364 - ERROR - Graphormer mapping failed for reaction 'CO.O=C(O)c1ccc(Br)c(C(F)(F)F)c1>>COC(=O)c1ccc(Br)c(C(F)(F)F)c1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:59:02,921 - ERROR - Graphormer mapping failed for reaction 'CC(C)[Si](OC[C@H](O)COCc1ccccc1)(C(C)C)C(C)C.Oc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1>>CC(C)[Si](OC[C@H](COCc1ccccc1)Oc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1)(C(C)C)C(C)C.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:59:17,440 - ERROR - Graphormer mapping failed for reaction 'C=CCc1cc(OCC(=O)O)ccc1O.CCO>>C=CCc1cc(OCC(=O)OCC)ccc1O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:59:18,950 - ERROR - Graphormer mapping failed for reaction 'CC(C)O.O=C(O)c1ccccc1S>>CC(C)OC(=O)c1ccccc1S.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:59:22,081 - ERROR - Graphormer mapping failed for reaction 'CCCCCCCCCCCCCCCCNc1ccc(CCC(=O)O)cc1.OCCCO>>CCCCCCCCCCCCCCCCNc1ccc(CCC(=O)OCCCO)cc1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:59:26,638 - ERROR - Graphormer mapping failed for reaction 'CCOCCOc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1.CO>>CCOCCOc1ncc2cc(C(=O)Nc3cc(C(=O)OC)ccc3Cl)c(=O)[nH]c2n1.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:59:35,640 - ERROR - Graphormer mapping failed for reaction 'CO.Oc1ccccc1O>>COc1ccccc1O.O': mapping overlap -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/graphormer_wrapper.py", line 22, in map_with_graphormer - myrxn.reset_mapping() - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/attention.py", line 116, in reset_mapping - if self.fix_mapping(): # fix common mistakes in mechanisms - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/algorithms/mapping/fixmapper.py", line 67, in fix_mapping - m.remap(mapping) - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/molecule.py", line 333, in remap - h = super().remap(mapping, copy=copy) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/chython/containers/graph.py", line 168, in remap - raise ValueError('mapping overlap') -ValueError: mapping overlap -2024-06-24 16:59:41,769 - INFO - Successfully processed Internal Batch from 0 to 50016 -2024-06-24 16:59:41,769 - INFO - Completed mapping all reactions. -2024-06-24 16:59:41,769 - INFO - local_mapper process... -2024-06-24 18:00:55,362 - ERROR - Failed to process reaction '[H][H]..[NH3+]c1nc(-c2ccc(Oc3ccc(Cl)cc3)cc2)cs1.[Cl-]>>Cl.[NH3+]c1nc(-c2ccc(Oc3ccccc3)cc2)cs1.[Cl-]' due to error: 'NoneType' object has no attribute 'is_block' -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/local_mapper_wrapper.py", line 33, in map_with_local_mapper - result = mapper.get_atom_map(reaction) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/localmapper/localmapper.py", line 56, in get_atom_map - predictions = self.pred_pxr(rxns) - ^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/localmapper/localmapper.py", line 48, in pred_pxr - predictions = predict(self.model, self.device, rgraphs, pgraphs) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/localmapper/utils.py", line 75, in predict - rbg, pbg = dgl.batch(rgraphs), dgl.batch(pgraphs) - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/dgl/batch.py", line 164, in batch - if any(g.is_block for g in graphs): - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/dgl/batch.py", line 164, in - if any(g.is_block for g in graphs): - ^^^^^^^^^^ -AttributeError: 'NoneType' object has no attribute 'is_block' -2024-06-24 18:13:04,547 - ERROR - Failed to process reaction '[H][H]..Nc1cn[n+](C2CCCCC2)c(Cl)c1.[Cl-]>>Cl.Nc1cc[n+](C2CCCCC2)nc1.[Cl-]' due to error: 'NoneType' object has no attribute 'is_block' -Traceback (most recent call last): - File "/homes/biertank/tieu/Documents/Project/TACsy/SynTemp/SynTemp/SynAAM/local_mapper_wrapper.py", line 33, in map_with_local_mapper - result = mapper.get_atom_map(reaction) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/localmapper/localmapper.py", line 56, in get_atom_map - predictions = self.pred_pxr(rxns) - ^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/localmapper/localmapper.py", line 48, in pred_pxr - predictions = predict(self.model, self.device, rgraphs, pgraphs) - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/localmapper/utils.py", line 75, in predict - rbg, pbg = dgl.batch(rgraphs), dgl.batch(pgraphs) - ^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/dgl/batch.py", line 164, in batch - if any(g.is_block for g in graphs): - ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ - File "/homes/biertank/tieu/miniconda3/envs/SynITSG/lib/python3.11/site-packages/dgl/batch.py", line 164, in - if any(g.is_block for g in graphs): - ^^^^^^^^^^ -AttributeError: 'NoneType' object has no attribute 'is_block' -2024-06-24 18:39:07,883 - INFO - Completed consensus mapping for Data/DPO/USPTO_balance/USPTO_50K_reactions.json.gz using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-24 18:39:11,357 - INFO - Saved AAM results of Data/DPO/USPTO_balance/USPTO_50K_reactions.json.gz to Data/DPO/USPTO_balance/USPTO_50K_aam_reactions.json.gz diff --git a/Data/DPO/USPTO_balance/balance_log.txt b/Data/DPO/USPTO_balance/balance_log.txt deleted file mode 100644 index eb842c3..0000000 --- a/Data/DPO/USPTO_balance/balance_log.txt +++ /dev/null @@ -1,173 +0,0 @@ -2024-06-21 09:39:49 - INFO - Processing file Data/DPO/USPTO_50K.csv -2024-06-21 09:39:49 - ERROR - Failed to load database, attempting to read CSV. Error: Expecting value: line 1 column 1 (char 0) -2024-06-21 09:39:50 - INFO - Start Batch 1 | Size: 5000 -2024-06-21 09:39:53 - INFO - Run rule-based method. -2024-06-21 09:39:54 - INFO - Input data contains 101 balanced reactions. -2024-06-21 09:39:54 - INFO - Run rule-based method on 3215 reactions. -2024-06-21 09:39:55 - INFO - Find maximum-common-substructure for 1700 reactions. -2024-06-21 09:40:05 - INFO - MCS Progress 23.71% ETA 0:00:32 -2024-06-21 09:40:16 - INFO - MCS Progress 44.33% ETA 0:00:25 -2024-06-21 09:40:26 - INFO - MCS Progress 66.14% ETA 0:00:15 -2024-06-21 09:40:36 - INFO - MCS Progress 91.94% ETA 0:00:03 -2024-06-21 09:40:42 - INFO - Impute missing compounds from MCS. -2024-06-21 09:40:54 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:41:18 - INFO - Input data contains 3699 balanced reactions. -2024-06-21 09:41:18 - INFO - Run rule-based method on 1298 reactions. -2024-06-21 09:41:20 - INFO - DONE -2024-06-21 09:41:20 - INFO - Completed batch 1 -2024-06-21 09:41:20 - INFO - Start Batch 2 | Size: 5000 -2024-06-21 09:41:23 - INFO - Run rule-based method. -2024-06-21 09:41:24 - INFO - Input data contains 119 balanced reactions. -2024-06-21 09:41:24 - INFO - Run rule-based method on 3225 reactions. -2024-06-21 09:41:25 - INFO - Find maximum-common-substructure for 1673 reactions. -2024-06-21 09:41:35 - INFO - MCS Progress 22.49% ETA 0:00:34 -2024-06-21 09:41:46 - INFO - MCS Progress 44.35% ETA 0:00:25 -2024-06-21 09:41:56 - INFO - MCS Progress 66.69% ETA 0:00:15 -2024-06-21 09:42:06 - INFO - MCS Progress 91.95% ETA 0:00:03 -2024-06-21 09:42:10 - INFO - Impute missing compounds from MCS. -2024-06-21 09:42:23 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:43:02 - INFO - Input data contains 3708 balanced reactions. -2024-06-21 09:43:02 - INFO - Run rule-based method on 1291 reactions. -2024-06-21 09:43:06 - INFO - DONE -2024-06-21 09:43:06 - INFO - Completed batch 2 -2024-06-21 09:43:06 - INFO - Start Batch 3 | Size: 5000 -2024-06-21 09:43:09 - INFO - Run rule-based method. -2024-06-21 09:43:11 - INFO - Input data contains 112 balanced reactions. -2024-06-21 09:43:11 - INFO - Run rule-based method on 3292 reactions. -2024-06-21 09:43:12 - INFO - Find maximum-common-substructure for 1623 reactions. -2024-06-21 09:43:22 - INFO - MCS Progress 17.44% ETA 0:00:47 -2024-06-21 09:43:33 - INFO - MCS Progress 35.00% ETA 0:00:37 -2024-06-21 09:43:43 - INFO - MCS Progress 51.10% ETA 0:00:29 -2024-06-21 09:43:53 - INFO - MCS Progress 67.84% ETA 0:00:19 -2024-06-21 09:44:03 - INFO - MCS Progress 89.11% ETA 0:00:06 -2024-06-21 09:44:10 - INFO - Impute missing compounds from MCS. -2024-06-21 09:44:24 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:45:04 - INFO - Input data contains 3770 balanced reactions. -2024-06-21 09:45:04 - INFO - Run rule-based method on 1226 reactions. -2024-06-21 09:45:08 - INFO - DONE -2024-06-21 09:45:08 - INFO - Completed batch 3 -2024-06-21 09:45:08 - INFO - Start Batch 4 | Size: 5000 -2024-06-21 09:45:11 - INFO - Run rule-based method. -2024-06-21 09:45:13 - INFO - Input data contains 102 balanced reactions. -2024-06-21 09:45:13 - INFO - Run rule-based method on 3268 reactions. -2024-06-21 09:45:14 - INFO - Find maximum-common-substructure for 1656 reactions. -2024-06-21 09:45:24 - INFO - MCS Progress 18.38% ETA 0:00:44 -2024-06-21 09:45:35 - INFO - MCS Progress 34.16% ETA 0:00:38 -2024-06-21 09:45:45 - INFO - MCS Progress 52.76% ETA 0:00:27 -2024-06-21 09:45:55 - INFO - MCS Progress 69.10% ETA 0:00:17 -2024-06-21 09:46:05 - INFO - MCS Progress 89.55% ETA 0:00:05 -2024-06-21 09:46:12 - INFO - Impute missing compounds from MCS. -2024-06-21 09:46:30 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:47:09 - INFO - Input data contains 3727 balanced reactions. -2024-06-21 09:47:09 - INFO - Run rule-based method on 1271 reactions. -2024-06-21 09:47:12 - INFO - DONE -2024-06-21 09:47:12 - INFO - Completed batch 4 -2024-06-21 09:47:12 - INFO - Start Batch 5 | Size: 5000 -2024-06-21 09:47:16 - INFO - Run rule-based method. -2024-06-21 09:47:18 - INFO - Input data contains 102 balanced reactions. -2024-06-21 09:47:18 - INFO - Run rule-based method on 3187 reactions. -2024-06-21 09:47:20 - INFO - Find maximum-common-substructure for 1728 reactions. -2024-06-21 09:47:31 - INFO - MCS Progress 15.84% ETA 0:00:56 -2024-06-21 09:47:41 - INFO - MCS Progress 34.43% ETA 0:00:39 -2024-06-21 09:47:51 - INFO - MCS Progress 53.26% ETA 0:00:26 -2024-06-21 09:48:01 - INFO - MCS Progress 72.09% ETA 0:00:15 -2024-06-21 09:48:11 - INFO - MCS Progress 92.92% ETA 0:00:03 -2024-06-21 09:48:17 - INFO - Impute missing compounds from MCS. -2024-06-21 09:48:35 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:49:16 - INFO - Input data contains 3647 balanced reactions. -2024-06-21 09:49:16 - INFO - Run rule-based method on 1347 reactions. -2024-06-21 09:49:20 - INFO - DONE -2024-06-21 09:49:20 - INFO - Completed batch 5 -2024-06-21 09:49:20 - INFO - Start Batch 6 | Size: 5000 -2024-06-21 09:49:24 - INFO - Run rule-based method. -2024-06-21 09:49:26 - INFO - Input data contains 112 balanced reactions. -2024-06-21 09:49:26 - INFO - Run rule-based method on 3231 reactions. -2024-06-21 09:49:28 - INFO - Find maximum-common-substructure for 1672 reactions. -2024-06-21 09:49:38 - INFO - MCS Progress 16.69% ETA 0:00:52 -2024-06-21 09:49:49 - INFO - MCS Progress 34.95% ETA 0:00:40 -2024-06-21 09:49:59 - INFO - MCS Progress 54.88% ETA 0:00:26 -2024-06-21 09:50:10 - INFO - MCS Progress 73.46% ETA 0:00:15 -2024-06-21 09:50:20 - INFO - MCS Progress 92.84% ETA 0:00:03 -2024-06-21 09:50:26 - INFO - Impute missing compounds from MCS. -2024-06-21 09:50:41 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:51:22 - INFO - Input data contains 3684 balanced reactions. -2024-06-21 09:51:22 - INFO - Run rule-based method on 1314 reactions. -2024-06-21 09:51:26 - INFO - DONE -2024-06-21 09:51:26 - INFO - Completed batch 6 -2024-06-21 09:51:26 - INFO - Start Batch 7 | Size: 5000 -2024-06-21 09:51:31 - INFO - Run rule-based method. -2024-06-21 09:51:33 - INFO - Input data contains 114 balanced reactions. -2024-06-21 09:51:33 - INFO - Run rule-based method on 3190 reactions. -2024-06-21 09:51:35 - INFO - Find maximum-common-substructure for 1715 reactions. -2024-06-21 09:51:45 - INFO - MCS Progress 15.34% ETA 0:00:56 -2024-06-21 09:51:56 - INFO - MCS Progress 34.13% ETA 0:00:40 -2024-06-21 09:52:07 - INFO - MCS Progress 52.01% ETA 0:00:29 -2024-06-21 09:52:17 - INFO - MCS Progress 71.97% ETA 0:00:16 -2024-06-21 09:52:27 - INFO - MCS Progress 91.80% ETA 0:00:04 -2024-06-21 09:52:33 - INFO - Impute missing compounds from MCS. -2024-06-21 09:52:47 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:53:23 - INFO - Input data contains 3686 balanced reactions. -2024-06-21 09:53:23 - INFO - Run rule-based method on 1312 reactions. -2024-06-21 09:53:27 - INFO - DONE -2024-06-21 09:53:27 - INFO - Completed batch 7 -2024-06-21 09:53:27 - INFO - Start Batch 8 | Size: 5000 -2024-06-21 09:53:31 - INFO - Run rule-based method. -2024-06-21 09:53:33 - INFO - Input data contains 112 balanced reactions. -2024-06-21 09:53:33 - INFO - Run rule-based method on 3200 reactions. -2024-06-21 09:53:35 - INFO - Find maximum-common-substructure for 1708 reactions. -2024-06-21 09:53:46 - INFO - MCS Progress 14.85% ETA 0:01:03 -2024-06-21 09:53:56 - INFO - MCS Progress 32.73% ETA 0:00:43 -2024-06-21 09:54:07 - INFO - MCS Progress 49.28% ETA 0:00:32 -2024-06-21 09:54:17 - INFO - MCS Progress 66.88% ETA 0:00:20 -2024-06-21 09:54:27 - INFO - MCS Progress 87.69% ETA 0:00:07 -2024-06-21 09:54:35 - INFO - Impute missing compounds from MCS. -2024-06-21 09:54:50 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:55:25 - INFO - Input data contains 3649 balanced reactions. -2024-06-21 09:55:25 - INFO - Run rule-based method on 1350 reactions. -2024-06-21 09:55:29 - INFO - DONE -2024-06-21 09:55:29 - INFO - Completed batch 8 -2024-06-21 09:55:29 - INFO - Start Batch 9 | Size: 5000 -2024-06-21 09:55:32 - INFO - Run rule-based method. -2024-06-21 09:55:34 - INFO - Input data contains 102 balanced reactions. -2024-06-21 09:55:34 - INFO - Run rule-based method on 3210 reactions. -2024-06-21 09:55:35 - INFO - Find maximum-common-substructure for 1710 reactions. -2024-06-21 09:55:45 - INFO - MCS Progress 16.71% ETA 0:00:50 -2024-06-21 09:55:56 - INFO - MCS Progress 33.82% ETA 0:00:39 -2024-06-21 09:56:06 - INFO - MCS Progress 50.66% ETA 0:00:29 -2024-06-21 09:56:16 - INFO - MCS Progress 67.47% ETA 0:00:19 -2024-06-21 09:56:26 - INFO - MCS Progress 84.46% ETA 0:00:09 -2024-06-21 09:56:37 - INFO - Impute missing compounds from MCS. -2024-06-21 09:56:53 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:57:34 - INFO - Input data contains 3684 balanced reactions. -2024-06-21 09:57:34 - INFO - Run rule-based method on 1315 reactions. -2024-06-21 09:57:38 - INFO - DONE -2024-06-21 09:57:38 - INFO - Completed batch 9 -2024-06-21 09:57:38 - INFO - Start Batch 10 | Size: 5000 -2024-06-21 09:57:42 - INFO - Run rule-based method. -2024-06-21 09:57:44 - INFO - Input data contains 100 balanced reactions. -2024-06-21 09:57:44 - INFO - Run rule-based method on 3253 reactions. -2024-06-21 09:57:45 - INFO - Find maximum-common-substructure for 1670 reactions. -2024-06-21 09:57:56 - INFO - MCS Progress 16.15% ETA 0:00:56 -2024-06-21 09:58:07 - INFO - MCS Progress 33.83% ETA 0:00:41 -2024-06-21 09:58:17 - INFO - MCS Progress 48.04% ETA 0:00:33 -2024-06-21 09:58:27 - INFO - MCS Progress 66.85% ETA 0:00:20 -2024-06-21 09:58:37 - INFO - MCS Progress 88.08% ETA 0:00:06 -2024-06-21 09:58:45 - INFO - Impute missing compounds from MCS. -2024-06-21 09:59:00 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:59:37 - INFO - Input data contains 3708 balanced reactions. -2024-06-21 09:59:37 - INFO - Run rule-based method on 1289 reactions. -2024-06-21 09:59:41 - INFO - DONE -2024-06-21 09:59:41 - INFO - Completed batch 10 -2024-06-21 09:59:41 - INFO - Start Batch 11 | Size: 16 -2024-06-21 09:59:41 - INFO - Run rule-based method. -2024-06-21 09:59:41 - INFO - Input data contains 0 balanced reactions. -2024-06-21 09:59:41 - INFO - Run rule-based method on 9 reactions. -2024-06-21 09:59:41 - INFO - Find maximum-common-substructure for 7 reactions. -2024-06-21 09:59:42 - INFO - Impute missing compounds from MCS. -2024-06-21 09:59:42 - INFO - Run rule-based method again to fix remaining non-carbon imbalance. -2024-06-21 09:59:42 - INFO - Input data contains 10 balanced reactions. -2024-06-21 09:59:42 - INFO - Run rule-based method on 6 reactions. -2024-06-21 09:59:43 - INFO - DONE -2024-06-21 09:59:43 - INFO - Completed batch 11 -2024-06-21 09:59:43 - INFO - Reactions balanced and saved successfully. -2024-06-21 09:59:43 - INFO - Processing complete. diff --git a/Data/DPO/USPTO_unbalance/Complete/USPTO_unbalance_pipeline.log b/Data/DPO/USPTO_unbalance/Complete/USPTO_unbalance_pipeline.log deleted file mode 100644 index f19daee..0000000 --- a/Data/DPO/USPTO_unbalance/Complete/USPTO_unbalance_pipeline.log +++ /dev/null @@ -1,47 +0,0 @@ -2024-06-27 22:16:23,638 - INFO - Processing data USPTO_unbalance with 4 cpus -2024-06-27 22:16:36,775 - INFO - Fixing hydrogen for batch 1/41. -2024-06-27 22:16:54,981 - INFO - Fixing hydrogen for batch 2/41. -2024-06-27 22:17:13,232 - INFO - Fixing hydrogen for batch 3/41. -2024-06-27 22:17:32,610 - INFO - Fixing hydrogen for batch 4/41. -2024-06-27 22:17:51,034 - INFO - Fixing hydrogen for batch 5/41. -2024-06-27 22:18:09,569 - INFO - Fixing hydrogen for batch 6/41. -2024-06-27 22:18:27,823 - INFO - Fixing hydrogen for batch 7/41. -2024-06-27 22:18:46,558 - INFO - Fixing hydrogen for batch 8/41. -2024-06-27 22:19:04,922 - INFO - Fixing hydrogen for batch 9/41. -2024-06-27 22:19:28,213 - INFO - Fixing hydrogen for batch 10/41. -2024-06-27 22:19:47,891 - INFO - Fixing hydrogen for batch 11/41. -2024-06-27 22:20:06,328 - INFO - Fixing hydrogen for batch 12/41. -2024-06-27 22:20:26,121 - INFO - Fixing hydrogen for batch 13/41. -2024-06-27 22:20:48,094 - INFO - Fixing hydrogen for batch 14/41. -2024-06-27 22:21:10,499 - INFO - Fixing hydrogen for batch 15/41. -2024-06-27 22:21:33,125 - INFO - Fixing hydrogen for batch 16/41. -2024-06-27 22:21:52,020 - INFO - Fixing hydrogen for batch 17/41. -2024-06-27 22:22:15,384 - INFO - Fixing hydrogen for batch 18/41. -2024-06-27 22:22:34,598 - INFO - Fixing hydrogen for batch 19/41. -2024-06-27 22:22:56,216 - INFO - Fixing hydrogen for batch 20/41. -2024-06-27 22:23:18,205 - INFO - Fixing hydrogen for batch 21/41. -2024-06-27 22:23:37,648 - INFO - Fixing hydrogen for batch 22/41. -2024-06-27 22:23:58,893 - INFO - Fixing hydrogen for batch 23/41. -2024-06-27 22:24:18,372 - INFO - Fixing hydrogen for batch 24/41. -2024-06-27 22:24:37,853 - INFO - Fixing hydrogen for batch 25/41. -2024-06-27 22:24:57,358 - INFO - Fixing hydrogen for batch 26/41. -2024-06-27 22:25:19,854 - INFO - Fixing hydrogen for batch 27/41. -2024-06-27 22:25:38,655 - INFO - Fixing hydrogen for batch 28/41. -2024-06-27 22:25:58,370 - INFO - Fixing hydrogen for batch 29/41. -2024-06-27 22:26:16,548 - INFO - Fixing hydrogen for batch 30/41. -2024-06-27 22:26:36,211 - INFO - Fixing hydrogen for batch 31/41. -2024-06-27 22:26:55,202 - INFO - Fixing hydrogen for batch 32/41. -2024-06-27 22:27:15,453 - INFO - Fixing hydrogen for batch 33/41. -2024-06-27 22:27:34,192 - INFO - Fixing hydrogen for batch 34/41. -2024-06-27 22:27:53,676 - INFO - Fixing hydrogen for batch 35/41. -2024-06-27 22:28:13,190 - INFO - Fixing hydrogen for batch 36/41. -2024-06-27 22:28:32,189 - INFO - Fixing hydrogen for batch 37/41. -2024-06-27 22:28:53,273 - INFO - Fixing hydrogen for batch 38/41. -2024-06-27 22:29:14,772 - INFO - Fixing hydrogen for batch 39/41. -2024-06-27 22:29:38,842 - INFO - Fixing hydrogen for batch 40/41. -2024-06-27 22:29:42,371 - INFO - Fixing hydrogen for batch 41/41. -2024-06-27 22:30:47,610 - INFO - Combining and save data -2024-06-27 22:30:47,611 - INFO - Number of correct mappers:27577 -2024-06-27 22:30:47,611 - INFO - Number of incorrect mappers:9512 -2024-06-27 22:30:47,611 - INFO - Number of uncertain hydrogen:2923 -2024-06-27 22:31:18,010 - INFO - Execution time: 894.37 seconds diff --git a/Data/DPO/USPTO_unbalance/Raw/USPTO_unbalance_pipeline.log b/Data/DPO/USPTO_unbalance/Raw/USPTO_unbalance_pipeline.log deleted file mode 100644 index 79f72e7..0000000 --- a/Data/DPO/USPTO_unbalance/Raw/USPTO_unbalance_pipeline.log +++ /dev/null @@ -1,6 +0,0 @@ -2024-07-04 14:09:46,830 - INFO - Processing data USPTO_unbalance with 4 cpus -2024-07-04 14:17:02,333 - INFO - Combining and save data -2024-07-04 14:17:02,333 - INFO - Number of correct mappers:30500 -2024-07-04 14:17:02,333 - INFO - Number of incorrect mappers:9512 -2024-07-04 14:17:02,333 - INFO - Number of uncertain hydrogen:0 -2024-07-04 14:17:38,822 - INFO - Execution time: 471.99 seconds diff --git a/Data/DPO/USPTO_unbalance/aam_log.txt b/Data/DPO/USPTO_unbalance/aam_log.txt deleted file mode 100644 index 49f9b18..0000000 --- a/Data/DPO/USPTO_unbalance/aam_log.txt +++ /dev/null @@ -1,48 +0,0 @@ -2024-06-21 09:38:47,743 - INFO - Starting processing of Data/DPO/USPTO_50K.csv -2024-06-21 09:38:47,749 - ERROR - Failed to load database, trying to read CSV. Error: Expecting value: line 1 column 1 (char 0) -2024-06-21 09:38:47,880 - INFO - Starting consensus mapping for Data/DPO/USPTO_50K.csv using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-21 09:38:47,880 - INFO - rxn_mapper process... -2024-06-21 09:38:58,414 - INFO - Starting mapping of 10 reactions in batches of 10. -2024-06-21 09:38:58,414 - INFO - Processing batch from index 0 to 10. -2024-06-21 09:38:58,924 - INFO - Successfully processed Internal Batch from 0 to 10 -2024-06-21 09:38:58,924 - INFO - Completed mapping all reactions. -2024-06-21 09:38:58,924 - INFO - graphormer process... -2024-06-21 09:39:01,151 - INFO - Starting mapping of 10 reactions in batches of 10. -2024-06-21 09:39:01,151 - INFO - Processing batch from index 0 to 10. -2024-06-21 09:39:04,207 - INFO - Successfully processed Internal Batch from 0 to 10 -2024-06-21 09:39:04,207 - INFO - Completed mapping all reactions. -2024-06-21 09:39:04,207 - INFO - local_mapper process... -2024-06-21 09:39:12,496 - INFO - Completed consensus mapping for Data/DPO/USPTO_50K.csv using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-21 09:39:12,499 - INFO - Saved AAM results of Data/DPO/USPTO_50K.csv to Data/DPO/USPTO_unbalance/USPTO_50K_aam_reactions.json.gz -2024-06-21 09:41:47,235 - INFO - Starting processing of Data/DPO/USPTO_50K.csv -2024-06-21 09:41:47,243 - ERROR - Failed to load database, trying to read CSV. Error: Expecting value: line 1 column 1 (char 0) -2024-06-21 09:41:47,423 - INFO - Starting consensus mapping for Data/DPO/USPTO_50K.csv using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-21 09:41:47,423 - INFO - rxn_mapper process... -2024-06-21 09:41:50,780 - INFO - Starting mapping of 10 reactions in batches of 10. -2024-06-21 09:41:50,780 - INFO - Processing batch from index 0 to 10. -2024-06-21 09:41:51,254 - INFO - Successfully processed Internal Batch from 0 to 10 -2024-06-21 09:41:51,254 - INFO - Completed mapping all reactions. -2024-06-21 09:41:51,255 - INFO - graphormer process... -2024-06-21 09:41:51,460 - INFO - Starting mapping of 10 reactions in batches of 10. -2024-06-21 09:41:51,461 - INFO - Processing batch from index 0 to 10. -2024-06-21 09:41:53,458 - INFO - Successfully processed Internal Batch from 0 to 10 -2024-06-21 09:41:53,458 - INFO - Completed mapping all reactions. -2024-06-21 09:41:53,459 - INFO - local_mapper process... -2024-06-21 09:41:56,841 - INFO - Completed consensus mapping for Data/DPO/USPTO_50K.csv using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-21 09:41:56,843 - INFO - Saved AAM results of Data/DPO/USPTO_50K.csv to Data/DPO/USPTO_unbalance/USPTO_50K_aam_reactions.json.gz -2024-06-21 09:42:10,969 - INFO - Starting processing of Data/DPO/USPTO_50K.csv -2024-06-21 09:42:10,974 - ERROR - Failed to load database, trying to read CSV. Error: Expecting value: line 1 column 1 (char 0) -2024-06-21 09:42:11,097 - INFO - Starting consensus mapping for Data/DPO/USPTO_50K.csv using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-21 09:42:11,099 - INFO - rxn_mapper process... -2024-06-21 09:42:12,690 - INFO - Starting mapping of 50016 reactions in batches of 50016. -2024-06-21 09:42:12,691 - INFO - Processing batch from index 0 to 50016. -2024-06-21 10:00:58,479 - INFO - Successfully processed Internal Batch from 0 to 50016 -2024-06-21 10:00:58,480 - INFO - Completed mapping all reactions. -2024-06-21 10:00:58,480 - INFO - graphormer process... -2024-06-21 10:00:58,643 - INFO - Starting mapping of 50016 reactions in batches of 50016. -2024-06-21 10:00:58,644 - INFO - Processing batch from index 0 to 50016. -2024-06-21 11:15:11,634 - INFO - Successfully processed Internal Batch from 0 to 50016 -2024-06-21 11:15:11,635 - INFO - Completed mapping all reactions. -2024-06-21 11:15:11,635 - INFO - local_mapper process... -2024-06-21 12:51:02,972 - INFO - Completed consensus mapping for Data/DPO/USPTO_50K.csv using ['rxn_mapper', 'graphormer', 'local_mapper'] -2024-06-21 12:51:05,738 - INFO - Saved AAM results of Data/DPO/USPTO_50K.csv to Data/DPO/USPTO_unbalance/USPTO_50K_aam_reactions.json.gz diff --git a/Data/USPTO_50K/USPTO_50K.csv b/Data/USPTO_50K.csv similarity index 100% rename from Data/USPTO_50K/USPTO_50K.csv rename to Data/USPTO_50K.csv diff --git a/Data/USPTO_50K/USPTO_50K_original.csv b/Data/USPTO_50K_original.csv similarity index 100% rename from Data/USPTO_50K/USPTO_50K_original.csv rename to Data/USPTO_50K_original.csv diff --git a/Docs/Analysis/_templates_analysis.ipynb b/Docs/Analysis/_templates_analysis.ipynb index 03e4b74..3306ca5 100644 --- a/Docs/Analysis/_templates_analysis.ipynb +++ b/Docs/Analysis/_templates_analysis.ipynb @@ -2,37 +2,213 @@ "cells": [ { "cell_type": "code", - "execution_count": 1, + "execution_count": 22, "metadata": {}, "outputs": [], "source": [ "import sys\n", "sys.path.append('../../')\n", - "from SynTemp.SynUtils.utils import load_database, load_from_pickle\n", - "templates = load_from_pickle('../../Data/Temp/templates.pkl.gz')\n", - "data_cluster = load_from_pickle('../../Data/Temp/data_cluster.pkl.gz')\n", - "original = load_database('../../Data/Temp/USPTO_50K_reactions.json.gz')" + "from SynTemp.SynUtils.utils import load_database, load_from_pickle" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "## 1. Split data" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [], + "source": [ + "import pandas as pd\n", + "from SynTemp.SynUtils.utils import train_val_test_split_df, save_database\n", + "original_data = load_database('../../Data/Temp/data_aam.json.gz')\n", + "original_data = pd.DataFrame(original_data)\n", + "\n", + "train, test, valid = train_val_test_split_df(original_data, target='class')\n", + "train, test, valid = train.to_dict('records'), test.to_dict('records'), valid.to_dict('records')\n", + "\n", + "save_database(train, '../../Data/Temp/Benchmark/train.json.gz')\n", + "save_database(test, '../../Data/Temp/Benchmark/test.json.gz')\n", + "save_database(valid, '../../Data/Temp/Benchmark/valid.json.gz')" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": {}, + "outputs": [], + "source": [] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Count number of templates" + ] + }, + { + "cell_type": "code", + "execution_count": 23, + "metadata": {}, + "outputs": [], + "source": [ + "raw = load_from_pickle('../../Data/Temp/Benchmark/Raw/templates.pkl.gz')\n", + "complete = load_from_pickle('../../Data/Temp/Benchmark/Complete/templates.pkl.gz')\n", + "expand = load_from_pickle('../../Data/Temp/Benchmark/Expand/templates.pkl.gz')" + ] + }, + { + "cell_type": "code", + "execution_count": 24, + "metadata": {}, + "outputs": [], + "source": [ + "def calculate(data):\n", + " number = []\n", + " for i in range(len(data)):\n", + " number.append(len(data[i]))\n", + " return number" + ] + }, + { + "cell_type": "code", + "execution_count": 25, + "metadata": {}, + "outputs": [], + "source": [ + "raw_result = calculate(raw)\n", + "complete_result = calculate(complete)\n", + "expand_result = calculate(expand)" + ] + }, + { + "cell_type": "code", + "execution_count": 26, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "[313, 1577, 9798, 22248]\n", + "[297, 1499, 9448, 21638]\n", + "[341, 1626, 9964, 22731]\n" + ] + } + ], + "source": [ + "print(raw_result)\n", + "print(complete_result)\n", + "print(expand_result)" + ] + }, + { + "cell_type": "markdown", + "metadata": {}, + "source": [ + "# Analyze descriptors" ] }, { "cell_type": "code", - "execution_count": 2, + "execution_count": 15, "metadata": {}, "outputs": [], "source": [ - "temp_0 = templates[0]" + "complete = load_from_pickle('../../Data/Temp/Benchmark/Complete/templates.pkl.gz')\n", + "data_cluster = load_from_pickle('../../Data/Temp/Benchmark/Complete/data_cluster.pkl.gz')\n", + "temp_0 = complete[0]" ] }, { "cell_type": "code", - "execution_count": 41, + "execution_count": 21, "metadata": {}, "outputs": [ { "data": { - "image/png": "iVBORw0KGgoAAAANSUhEUgAABkUAAAVnCAYAAADsZGrwAAAAOXRFWHRTb2Z0d2FyZQBNYXRwbG90bGliIHZlcnNpb24zLjguMywgaHR0cHM6Ly9tYXRwbG90bGliLm9yZy/H5lhTAAAACXBIWXMAAA9hAAAPYQGoP6dpAAEAAElEQVR4nOz9e3xU95nn+37XKt2FSuJiwEDhCza2EU58I2lkJ90JpAF3T0+bSSLPnL6YHmP2nEnsOXubyWSfmP3axKczHdiv2ab77Bkbz+Cenn0GORnS05MYkdjOxUEkvidI2NjcTHE3F6l0V1Wt3/ljUbKELkiiqtbt83699MKuKlX9VFJVrWc9v+d5LGOMEQAAAAAAAAAAQMjZXi8AAAAAAAAAAACgGEiKAAAAAAAAAACASCApAgAAAAAAAAAAIoGkCAAAAAAAAAAAiASSIgAAAAAAAAAAIBJIigAAAAAAAAAAgEggKQIAAAAAAAAAACKBpAgAAAAAAAAAAIiEEq8XAETdli1btHHjRq+XAQAoImOM0um0HMfxeimAJ2zbVmlpqSzL8nopAAAAgUZsgaibSmxBUgTwUEtLi55//nndf//9amhoKPrjb9++Xc8999yIy2trayVJHR0dE7pcktasWaPNmzcXYJX+sWnTJrW2tiqVSimZTOqNN95QPB73elkFca0/6+OPP64TJ04olUqpo6NDb7zxRgFXCwRHNpvV+fPn1dnZqXQ67fVyAE+VlpaqpqZGs2bNUiwW83o5AAqsra1NjzzyiFKp1LDL4/H4YJyR09HRoUQioaVLl2r16tVFiZUmur6Ojg6lUiklEgktWbJEDz/8sCexXCFwDA8EC7EF8InJxhYkRQAP7dy5U5LU3NzsyYF0MplUKpXSqlWrtGHDBiUSiWEnvpPJpFauXClJeuaZZ7R69eph39/W1qaXXnpJzz//vFpbW4u6di80Njaqvr5emzZt8nopBXetP+vDDz+sZDIZiecKmKhsNqtkMqn+/n7V1tZq2rRpisVi7JRH5BhjlM1m1dXVpfb2dvX29iqRSJAYAUKuvr5+8CT72rVr1dbWpkcffXTMqvlkMqnt27dr3bp1amho0ObNm5VIJIq6vsbGxjE3fuVioSeeeEKJRELPPPNMQddXDBzDA8FBbAG4phpbkBQBPLRv3z5J0u7duz2pskgmk+Me6A89qB/tAL++vl719fWqq6tTU1NTwdbpF7mfd+/evdqzZ4/XyymoifysyWRS69at05IlS7Rt27Zh1+WSfE1NTWprayv4eoEgOH/+vPr7+7Vw4UJVVlZ6vRzAc9OmTVNtba2OHz+u8+fPa86cOV4vCUCRLFiwQG1tbaqrqxvzNolEQps3bx7cqLNu3Tq9/PLLRV1fTU3NmLfJHS9v2LBBjzzyiFauXKldu3apvr6+KGssBI7hgeAgtgCGm2xswaB1wCPNzc168sknFY/HlUql1NzcXPQ1dHR06Mknn5zQbcdrnbR+/fp8LQlyy9aDoLm5WclkctwE0ZWtEICoMsaos7NTtbW1BC3AEJWVlYrH4+rs7JQxxuvlACiS8ZIhV8pVMCeTyaIdJ+fWN5F1xuNx7dq1S4lEQmvXrlUymSzYuor183MMD/gbsQUwusnEFiRFAI+89NJLWrNmjdasWTP4/8VWW1ubt5kYQS8Vn4zJBHFTceLEiYLe/2SM97M2NjaOW2kE4BPpdFrpdFrTpk3zeimA79TU1Ay+RgBgNI899pgk+bpa+5lnnpEkPfHEEwV7DD/FCQC8Q2wBjG2isQVJEcADueF98Xh8cE6HFwf445WDT1aUkiKFVsjdZfkUj8e1efNmNTY2er0UwPccx5EkZiYAo8i9LnKvEwC40tBYw69tnerr69XQ0KC2traCtRYOSpwAoLCILYCxTTS2ICkCeGD37t168MEHJbl9W3PVGsVuoZXPiodEIsFBeh60tLQMJs0AhA+DD4GReF0AuJqOjo7B/85XpXsh5NoKb9++Pe/3TZwA4EocQwEjTfR1QVIE8EBzc/NghYgkffWrX5Wkog8rH7qGa9XQ0EDv2TwoRAAFAAAABFmuOiQej/u6Qj03qDyZTKqlpSWv902cAABA/pAUAYoslUqNaFuVqxop9u6f3EF7PtTX1/t611YQbNq0Ke/BEwAAABBkqVRKzz33nKRP5nb4WS5ps3fv3rzdJ3ECAAD5VeL1AoCoaWpq0sMPPzzssvr6+sH2U7t37w7FjIaWlhbt3LlzWIuumpoabdy4cdjtNm3apNbWVqVSKSWTSR08eFCSuxOqvb1dnZ2dam1t1YIFC7Rx48bBICOZTGrnzp2D/33ixAktX758xP3nPP744zpx4oRSqZQ6Ojr0xhtvKJVK6dlnn1VnZ6fa29t14MABNTQ0aP369de8A625uVn79++XpMH737Bhg+rr60fctqmpacTOr2XLlg2rvGloaBhzoPlEn+t82r59u1paWpRMJpVMJvXGG29cNSmWSqXU1NSk9vZ2Se7vra6uTk8++eSo3zv0dyZJL7/8slKplLZu3aqamholk0k9+OCDo1Y8Teb5n+xjbdq0Sbt37x5xH6+88sqIn2Pt2rVqa2tTPB5XKpXSqlWrtG3btnGfJwAAALhSqZQeeeQRpVIpbd68Oa+bugolF9cdOHBg1OuLGSdM9ph4NJM9hr/Wx8/FeQsXLhw8Nm9vb9eDDz6olpYWNTQ0jPr9XsREAIDgIikCFFlLS8tgr9mhGhsbtXXrVjU1NQU+KbJlyxbt27dPzzzzzLDkwqZNm7Ry5Urt2LFj8PLGxkY1NDToiSeeGHa7KxMT69at09q1a/XKK68omUzqpZdeGnaAm0qltGLFCiWTyVFPOm/YsEHJZHLwcZLJpJqbm0dN0qxdu1bf/va3p9xebMuWLbr//vuH3XdbW5seeeQRrVmzZkTQ0tjYOPg7X7dunVpaWvTGG29M+LEm+lznU0NDgxKJhJ566qkJ3b6trW3Uv/3m5matWLFi1Od7w4YNam1t1aZNm5RIJJRKpfStb31L27ZtUyqV0rJly7Rnz57BRFrOZJ//yT7W5s2btXnzZm3atElNTU3jJjp27dqltWvXKpVK6YUXXphUAArkUy7xl2s/smrVqmHXd3Z2qrGxMa9tFYsllUpp7dq1amxsHPXztZhyr/d4PK4FCxZIcp/b3MytJUuWjLhs/fr1gf/cB4B8yx07Pvfcc1q+fLm+/e1vB+Y4KtcVYLR5i8WOEyZ7THylqRzDX8vjNzc366WXXhr12HrLli16/vnntWvXrlGv8yImAqKK2KI4iC0KzAAomuPHj5unnnpqzOsWL15sFi9ebDo6Ooq8srHl1nT8+PEJ3f673/3uuLdfsWKFeeihh0Zc/sgjj5jFixeb7373u6P+/K2trYPXj/UcXu2xjTHmoYceGryfsXz96183ixcvNnv37h31+qeeemrM39Pu3bvN7t27R/2+3bt3m8WLF5udO3eO+di552EipvpcT8Z4P6sxnzxXY10/9Pc6ltzzMtbz/dBDD5kVK1aM+L1//etfH3G/1/r8T+axOjo6zOLFi80jjzwy5v0Z4z6Hra2t494G4dfb22sOHDhgent7PV3H4sWLR31f6OjoMA899JB56KGHfPUZNNRY7yO5z8+vf/3rRV7RSIsXLx7xHjTWe0VHR8eo7y1R5JfXB4DiyR1jPvTQQ+a73/3uqF9f//rXzVNPPWV27txZ9M+m3Pqee+65KX/vfffdN+zyYsYJ+XqsqR7DT/Xx77vvvnF/1ytWrBhxXF2MmAjwG78cOxFbFBaxxdRM9PXBTBGgiHbu3DlmxjaRSAzufir2wPV8SSaTev755/Xoo4+OuRNn/fr1gzuOhho6Z2W0Muzcc/P888+P+RzeeeedkjRuv91cqfmVLcyGyu1m2rRp05i3GUtLS4ueeuqpUdeQ2yWRj9/vtTzX+TS0PH08GzZsGPO61atXK5FIjPl819bWKplMjvg5t23bNqLS51qf/8k8Vjwe16pVqwbbiI0nKDsbEV3xeFwvvPDC4A5OPxrrdZZIJHTw4EFftKZbtWrVmDvirpwnFo/H9fTTT6uzs7MYSwMAX1qzZo02btw46te2bdu0efNmtbW1admyZYEbND60xZVUvDghn4811WP4qTx+KpUabHU8lit3o/slJgIwHLFFfhBbFBZJEaCIDhw4MO7J0TVr1kgKblJky5YtkqT7779/zNssXbpU0tiDB8f73pyrnWCeyLD68cqnE4mEVq1apWQyOenfRXt7u1Kp1GAZ6Wj3fbUT6BORj+e6mK7Wb3giz/dEekjn6/mfaL/qXHItN9/mSs3NzYEsGUY0xeNxxeNxtbW1Teh9tJiam5t9f4CfSqUm9Bk2VDweHxHQAACG27x5sx599FFt3bpVjz/+uNfLuarc7I0rj3+LFSfk87Gmegw/lcfPPdYTTzwx5nHIgw8+OGxNQYuJgCghtrg2xBaFR1IEKJLc7pSVK1eO+fXcc89J0uDw6qDJDRPMHXiOJpeMGGvw4NV6vY53/dUO2icjV3Uy2YPnp59+Ws8888yYvSdzA7evVT6eaz9ZuHChpPGf74n0Ac7X8z/RnsO52SovvvjiqNe/9NJLgRgICuTkXh/5fD+9VslkcsLzi7w0WpUZACA/Nm7cqHg8rj179vh+A1nuRNuVx+nFihOK+VhjHcNP9fGHVgatXbtWW7ZsGVbhUV9fP+yzNmwxERA2xBZTR2xReAxaB4rkpZde0q5du65a5ZAboLdz584R7Xr8LpfIefbZZ8dtq/Tkk0+O+eZ+ZZn5lYr1YZpb34kTJyb1ffF4fLAyIDfMff/+/YP3l69kVz6eaz/J/d7He74n8rvP1/M/mb+zxsZGbd26dURVSDKZHEyuAUHQ3NwsyX3fGE0qldLWrVuVSCTU3t6uZDKpDRs2jPhcSyaT2rlzp+rq6gZ3y473edbU1KS2trbBXU3333//YDIxN3BVklpbWwd3CCcSCW3cuFHJZFKbNm1Sa2urEonEqMNXh7ZbaW9v18KFC4e1YWxra9NTTz2lZDKp5cuX6+mnn1ZTU5Pi8bj27t07+FhXM9U2eRs3blRTU9Pg8xCPx/XVr3518DGbm5v1xBNPSHITsevXr9fWrVsH1/vwww8PnozKBU/jrXeiv0cA8JuvfvWrev7557V9+3ZfD5HNncS/cmNMseKEYj7WWMfwU338xsZGJRIJbd26VW1tbWpra9Pzzz8vya1Kefrpp4cdp4ctJgLChNiC2MLvSIoARXLgwIEJvfGtXr1aLS0t2rNnT6CSIkN3+mzYsMFXOwGKrbm5efBDYf369cN2SO3bt2/MMvKJ4rkeX6Gf/yvlkiLPPffcsKTIzp07x+3DDPhF7mTF7t279cwzz4za8i2ZTGrt2rV64YUXBg9wR7tMcgOFzZs3D/7/li1btHbt2lGDiscff1x1dXUjbi+5B+mrV6/W6tWrtW7dOkka0ds3kUhox44dWrdu3ag9yNeuXavHHnts2M+0ZcsWPf7444P3VV9fr127dmndunXq7OxUU1PT4PtGY2Ojli1bprq6ujF3u+ZDY2OjGhsbtXLlyhGBx+rVq/Xoo48OC7h27dqltWvXat++fbr//vuH3f7xxx8f8/mezO8RAPwmV5Xg54r6oceZo32eFvM4tdjHxPl6/IaGBu3atUupVEotLS3av3+/9u3bpz179mjfvn3atWuXEokEMRHgU8QWxBZBiS1onwUUQUtLy4Rb6OTmiiSTyYIfqOZT2A5C9+/fL0lasGDBpL5v06ZNeuKJJ9TY2KgdO3bkrXVSU1PTYAAYtuda0uABx2Sf7ysV6vkfT27gem43W05nZ2cof1cIvlQqpe3btw9+bdmyRbt379a3v/3tMWfgbNq0ScuXLx92YJtIJLR8+XJt3bp18LKWlhY1NTUNa3WxYcMGtbW1De4Wy2lqatKePXtG7B7bs2fPmHN6xjLa7s9NmzaptrZ2xM+0ceNG7du3b8R6ampq1NLSMuL2S5cu1e7duye1nqlqbGwccxDslbuia2trlUgkRlz+9NNPq62tbTAAHGqiv0cAwNTkdiA/+uijI64rRpxQ6Me60ljH8FN5/FQqNeyzOVdtsnHjRu3atUs7duxQKpUaHOzOcTbgD8QWxBZBjS1IigBFMJlhy/F4fPCg0e/9cq+0atUqSW4ZYtDles5OZrBV7gM7V4I4mit757a1tU1pt1uYnmvpk111Dz744JTvo5jP/5VyFSG51ywD1uFn8Xh8cMfm+vXrtW3bNj322GNau3btiIN5SYM7NUdrB3f//fcPex9KJBKDs3aGPp40cmfv1q1btWrVqhEnNZYsWXJN7wU5TU1NY74ORztQr6urUzweHxEEFbPdRi4IGfr5n0qlxmwJMlrLyVyi9spZR5P5PQKAH+WOF/268zSVSun5559XPB4fUS1czOPUYj7WaMfwU3389957b9z4t6GhQU8++eSwE3xhi4mAICK2ILa4UlBiC5IiQBFMdkBS7o2rWNnjfMmV2F0tC59KpUbNMhfTeIMFk8mkWlpaRs2Sjyf3gT/eyfArP7iTyeSoa7nyslQqNewDKkjPdW4d49m9e7fq6+uvKZGQz+d/snJDH3MHGwxYR9CsXr1a9fX1ow4dzB3QJpPJwf60uS9peJ/gXMl5rq3F0F1cuR7AkvuekEqlRv1s3LZt2zUnFXMnacaaU1VXVzfqyZ+rzbUqtNzGiKGBy+7duyfdOz/3/A99f5vM7xEA/Cb33iWN3N3qF7ke7c8888yIk3LFjBMK+VhXGu0YfqqP39XVNeaO5pyGhoZhz23QYiIgKogtNO7ti4XYYnwkRYACa2pq0pIlSyb1Pbk37Fzmdbz7zpUPF9pEThwnEglt3rxZe/bsGXfdzz77rB5++OF8Lk/SxNY4dA1jyR0w79ixY9Trh374DpX7AB5rHc3NzSN2tnV0dAw7sM+dSB8tUBh6u2I912P9rBO9XnI/iMd7vrdv365UKqVnnnlmkqsbLh/P/7XI7YTbtGkTA9YRSAsWLFAqlRrx/pM7mG9oaBjsT3vl11DNzc1at27d4Ot+9erVI15nuXYb4w1FHc/V3u9H6wE8EX5oxdHY2Dhsx+7x48fzsq7J/h4BoJAmcgyZk0qlhg2FHev9Kp+xUW59E1lnKpXSunXr1NLSomeeeWbUjTHFjhOu9bGkqR/DT/Xxp02bJknjJi9yg4CHPpaX8SeAsRFbEFv4HUkRoIBaWlq0adMm7dmzZ9K70XNvUmP14cv1Ux2aic23oQeWV9u1k9PY2KjNmzfriSeeGLVUcsuWLbr//vtHZPBPnDghaezBibnnb7yy7tx1Eyn9vv/++0d93h5//HEdOHBgcDfCaMZaa2Njo+LxuJ577rkR17W0tCiZTOqxxx6T9MkOqra2tmGP09jYqEQiMez3fuVtht52Ks/1ZFzt93K16yV3h8CDDz446vOd+/vNDUwczUR/r/l4/ifzNzTa4+d+piAcAABjuXKe1dCheVfT1NSkp556Sps3b9bGjRvHbHGSe91NtX1da2vruN+7dOnSce+/vb29qKXrk5HbGLFz504lk8kpJVkPHDigeDw+LOCZzO8RAAotdww5XtIhN2NixYoVamtrG5xPMdZt8xkb5dbX2dk55m2SyaS2b9+uFStWKJlMateuXWPuRi5mnJCPx5Kmfgw/1cefN2+eJA0OJr5SW1ubnnvuOT399NMjHq/QMRGAqSO28BaxxdhKvF4AEEZtbW165JFHhp3IX7ZsmXbt2nXVHri5XUZD72vZsmWqra3VM888M/j9uTK4ZDKZ1zY9uaRAR0fHsETO1q1b9dxzzw1mg19++eUx76OxsVENDQ3avn27mpqahn04rF+/ftj/r127dli59iOPPKLa2lpt3rxZDQ0Namtr0xNPPDGYmU+lUoPPR24NucfJvRk3NTVp9+7dWrNmjTZv3jzqGnPPXW43WU1NjTo7O3XnnXdq27Zto37P1dYaj8f1yiuv6Nlnn9UTTzyhpUuXqqamRpJ05513DlYSbN68Wc8995xeeumlwZLvnHg8rh07dmjTpk1at26dEomEEonEmP14J/NcT8bVftaxrt+1a9ewD8olS5YMJgji8bi2bNmiuro6tbe3q7OzU4lEYsy/pZUrVw77O1y7dq1qa2u1ZMmSUX9H1/L8T/axxtLY2Kj29nZf7AgBJiu3s2rogW1bW5vq6+v16KOPqqmpadT3ok2bNg2+127dulVr1qwZ8d4z9PNk+/btWr9+vVatWjVmwv3K5GLuPXro/Y1Xjp7rfbt79+5R17xnz54xPx/8oLGxUS+++KLq6urGfP+XRt+1lqsyHa1kfaK/RwAohNxx/dDPmeeff14vvvjiiPf03HFZbmDrhg0bxo2j8hEbjba+XFxx5fpy7ZGXLFky7jDhoesrVpyQj8e6lmP4a3n8Rx99VBs3bhzcXChp8HsladeuXaM+ZqFiIgBTR2zhH8QWYzAAECGPPPKIWbx4sdfLQEjt3LnTtLa2er0M+FBvb685cOCA6e3t9eTxOzo6zN69e83ixYvNfffdZ44fP246OjqG3aa1tdUsXrzYPPLII4OXffe73x3874ceesg899xzw75n9+7dZu/evYP/v2LFimHfn7vNI488Yp566iljjBm8j46ODrNixYphj5Fbx+7du4ddtnPnTnPfffcN/v+V63jqqafMihUrRvzMK1asMDt37hxx2yvXaIwxX//610fcx3iXT1RHR8eI5/Vqcr+LK5+boR555BFz3333DXv+c+sd77Em8nssNq9fHwAAAEHi9bETscXw2xJbBDO2sIwxxuvEDAAUS64S5+DBg14vBSEUiN0Q8ERfX5+OHj2qm266SRUVFUV//NH6c4+2U6ilpUXbt28fnIX18MMPD9uZlbuf3M6vhoaGYTt3U6mUvvWtb6mzs3Nwp25u9+ymTZu0ZMkSbdiwYVg11ZYtWwZ3ncbjcSUSiVF3+W7ZskUHDhwYfMzcjuAtW7Zo3759SqVSWrVq1YjdxEPXnEwmVV9fP2yn2Gj3kfu5h16e65c70UGNmzZtUnt7uw4cODC4Q66hoUGJRGLEGkazcuXKYRWiV1q3bp0kdwdsrl/zaD/faK72eyw2r18fAAAAQeL1sROxBbHFUEGNLUiKAIgUkiIolGQyqZaWFuaJYFReBy4Ini1btoxoZzJULnAZq79+kPD6AAAAmDiOnTBZxBYjMWgdAIBJGq1X6fbt27VmzRoPVgMgbFKplBYuXOj1MgAAAAAEHLHF6EiKAAAwCVu2bNG6deu0ffv2wctyZaUMWAcwFW1tbcPaEOzevZskKwAAAIBJI7aYGJIiACIl13uxra3N45UgqO68804lEonB3p+pVEpbtmyhbRaAKXvppZe0Z88eSe57Sm1t7VWTrB0dHero6CjG8gAAAAAEBLHFxJR4vQAAKIaVK1eqo6NDqVRKkvTII4+otrZWmzdvHnXoFjCW1atXK5lMaufOnYOXPf300x6uCEDQbdiwQZIGK9CuHFI5VFtbm5599tnB5P7jjz+uhx9+mM8yAAAAAMQWE8SgdQAAgAJjGCIwNl4fAAAAE8exEzA2Bq0DAAAAAAAAAAAMQVIEAAAAAAAAAABEAkkRAAAAAAAAAAAQCSRFAAAAAAAAAABAJJAUAQAAAAAAAAAAkUBSBAAAAAAAAAAARAJJEQAAAAAAAAAAEAkkRQAAAAAAAAAAQCSQFAEAAAAAAAAAAJFAUgQAAMAnHGO8XsKkBXHNAAAAQNgF8Tg9iGtGMJV4vQAAAAC4bMvSa4f71NEbjGCgttLS5xZVXPP9pFIpfetb39KJEyfU1tYmSVq1atWw23R2diqZTCqZTCoej+uNN96QJCWTST3xxBNKJpNKJBLatWvXNa8HAAAACDpiC2ILjI2kCAAAgI909Bpd7HG8XsYE5afoOB6Pa9u2bUqlUlq2bJkSiYS2bds26m2bmpq0adMmpVIpxePxwWBl3bp16ujoyMt6/GbLli3auHGj18sAAABAwBBbEFtcidjCRfssAAAA+EI8Hh/272gaGxvV2NioZDI57PJEIlHQtXnpyp8VAAAAwPiILUZHbOEiKQIAAIBAWb16dWh3bl2publZnZ2dXi8DAAAACCVii2giKQIAAADfa2lpGfzvpUuXRmKHUzKZ1FNPPeX1MgAAAIBQIbYAM0UAAADge83NzWpoaJDklsA3NjZO6PtSqZS2bt2qRCKh9vZ2JZNJbdiwQfX19ZKktrY2PfXUU0omk1q+fLmefvppNTU1KR6Pa+/evaqrq9PmzZuVSqXU1NQkSdq/f78SicSovXiv9fFy99vc3KyXXnpJktTa2qrHH39ckkY8bjKZ1M6dO1VXV6f29nZJGrGulpYWbd26VclkUl/96lf14IMPqqWlRS0tLWpsbFRHR4eamprU1tameDyur371q4P30dzcrCeeeEKS1NDQoB07dkzoeQcAAAD8itiC2IKkCAAAAHwrFzDkDsonI5lMau3atXrhhRcGA4crL6uvrx8cptjZ2ammpiatX79ekttjeNmyZaqpqVFdXd3g5ZK0bNmyEZfl6/Fy97t69WqtW7dOksYcDrl9+3Zt3rx58P+3bNmitWvXateuXYOXNTQ0aNeuXVq5cqU6OzvV0tKi9evXq6mpSS+99JK2bdumxsZGrVy5ckRgtHr1aj366KNauHDhhINFAAAAwI+ILYgtcmifBQAAAF9JJpN6/PHH9fjjj+uJJ57Q1q1bp3Q/mzZt0vLlyweDCMndDbV8+fIR91lTU6OWlhatXr162OVLly7V888/P+rlu3fvLsjjXXm/Y2lpaVFTU9Ow8v8NGzaora1Nzc3NI26fSCS0e/fuwQBk165dwwKixsbGYfc1lNdBCwAAADAVxBbEFqMhKQIAXnOy0kCP1HFGSp2VOs9J3Relvk4p3edef7Xvd7KS4xRnvQBQYIlEQtu2bdO2bdu0Y8cOvfzyy5O+j1QqpZaWFt15550jrrv//vvV2to67LK6ujrF43ElEokRaxnr8lQqVZDHm6hEIqGGhoZh3xOPxyVpzL7IuZ9n6G1zcsFJrpRfcn+uurq6Ca8JAOCBXDyROid1nXdjiZ52qTcl9XVJ/d2Skxn5fcZ8EksYU/RlA0AxEFtMTNRiC9pnAYAfnD4gtY6TvbdsKVYqxcqkkstfZdVSebVUPs39t6xaqqhxv8qqpdLyT77fcSQZ934sq+A/DgDkUyKRGHFA39LSMtgHeDS5QCGZTA47EM958sknR1xWW1s76n2NdXmhHm+iEonEYB/eVCqlZDI5GLCM1RJgvMeMx+NqaGhQU1PTYBAzdPcXAMDHrhZPSJdjiGlSeZUbQwzGE0NiifJpUlmVe9uhHEey5MYTABBgxBaji1psQVIEAC4zxsjok01SlnX5uH+MJIJjjOxiJRiMI2X63a/+CX5PSZlUNX34V/UMqXqmVDHtk4DGyZIsAeB7GzZsGPb/e/fuHTdwyR2gNzQ0jCgjH8uVu5uudnmhHm88qVRq2Pc1NzerqalJS5Ys0YMPPqjVq1ePe781NTXj3n9jY6OeeOIJJZNJJRIJHT9+fErrBAD4UGZAylyUei5e/bZ2yeVkSZWbLJl2nRSfI9VeL1XVEUsACDRiC1eUYwuSIgBCzRgjx+SSG8MTHFnHqDdt1J8xGshKAxmjjGOUzkoDWfffTNZoIGuUyUqOkXJF5TXllj57Y/moj+kbmQG3HVfq7MjrLNtNjtTO/SS4iV//SXWJk738hLETDIA/XHnw3NnZOe7thw4jLIZiPV5ra+vg7rampiZt3bpVu3btmlRp/HhyQdfOnTv18MMPj1qyDwCIACcj9Xa4Xx2npbMffHKdHXOTJDWzpfhsKT7X/SqrdK83jrvTzI55s3YAuApiC1eUYwuSIgBCwXHMsKRHJmvUNWDU1e+oZ8B88pU26hlwLxu4yqiO8cysDniywDhS18fu18n9n1xeEb+cKJnrJkpqr3d3huW+Rxa7wAB4bqyBfVd69NFH1dTUpPXr14+4btOmTdq8eXNe11WIx6upqRkWpKVSqcGdY1u3btWaNWtGBC1D+xFv37591PWMp7GxUS+++KLq6uom/b0AgAhwslLqjPt1csjlZdVukqRmjvtv7fXuRiw7drn9FrEEAP8htohmbBHws3oAosZxjMyQIYD9GaOznVl9+HFGbxwf0E/e79X33unR/++tHv3D/l69+kG/fnVsQL89ldah8xmd6siqvffaEiKh1pdyd4F9+AvpzSbplf9T+vFW6Vd/J33wc+lS8pOB7lcbAA8ABdDW1qZNmzYN7p4aaugBuyRt3LhR8Xhc27dvH3Z5c3PziDL09vb2Ed9/tcuvVIjHu3KQYjKZHNzZVltbO2L3WHNzsxoaGsbc7Xa1XXCSG7ikUqkxewcDADCqgW7p/FHp6K+k3/yD9ItnpeZ/K+39j9KHP5cunSCWAOArxBbRjS0sM/TsIgD4iHP57cm2LBlj1NFrdK4rqwvdjjp6HXX0OerPeLO2mdW2/qC+Mj935mSl5DtXH4zoF7EyaeaN0nU3S7NvdXsKG6PBQe4ARujr69PRo0d10003qaKiYtzbvna4Tx29wTg8q6209LlF4/88E5FKpfStb31LJ06cUFtbmyRp1apVqqurk/RJkDD0+h07dqihoUHJZFJbtmzRvn37lEqltGrVKj388MPDegJv2bJFkgbvr6GhYVhJ+mjfn0gkJnR5Q0ODGhsbhwUm+Xi8ofe7ZcsWHThwYPB+cj9b7nnr7OwcvCy3jk2bNmnJkiXasGGDksmknn32We3Zs2fwub3zzjvH3am1cuVKPfPMM6MGiPk2mdcHAGAUQYonYmXSzBvcWOK6W6Xq6W4sYYxkE0sAE0FsMT5iC2KLibw+SIoA8A3HMbJtt5y6N210rjOr812Ozne7iZCM4/ECh4h0UuRKVdPdoGbWIvffWCkDF4ErTPTAzDFGdsBeN0FcM65uy5Yt2rhxY1Eei6QIAFyjIMcTlbXSrJuk6xZJs26WSito2wtcBbEFgsaPsQUzRQB4ZuiHXXuvo5PtWX3c5SZCetLkawOj55L00Vvul2VL0xe4Qc3sW9zZJJIbqDFoEbiqIAYAQVwzxpdKpbRw4UKvlwEAiILeDin5rvsly51veN0i96tugVs94jhUkQBTEMTj9CCuGePza2xBUgRA0RhjZOR+yPWljU52ZHW6I6vTqax6SYKEg3Gki8fdr4M/lcqq3B1fs26W5i6WSitJkACAz7S1temll14a3L21e/durVmzxuNVAQCix0gdp92vQ790W21dd7M0b6k0Z7G7AYs2WwDga0GJLUiKACioXEusrGN0rtPRyY5Php0jAgZ6pFOt7td+251Bkvi02z84twOEnSAA4KmXXnpJe/bs0caNG5VKpVRbWzs4cBEAAM9kB6Qz77tfJeXS3Nul+Z9yZ5LIiBZbAOA/QYktSIoAyLtcW6x01uj4paw+upjR6Y6ssuRBos040tmD7ldZlbvja+E9Us11VI8AgIc2bNggSdq+fbskjTskEQAAT2T6pRO/cb/Kp0nz6qUFn3Lb9RJLAIBvBCW2ICkCIC9yFSFuIiSjYxfd1lgOiRCMZqBHOva6+xWfIy34tBvU0F4LAIouHo8XbfAhAADXrL9LOvpr96tmtpS4y40nSiuYPwIAHgtKbEFSBMCUDa0I+ehiRh9ddOeDkAjBpKTOSgd+LL338uX2Wne5Q9olURIPAAAAYEyd59xY4v1XpDm3uZXoM2+UZNwZJAAAjIKkCIBJMeaTjMfJ9qw+/NidEUIiBNdsWHutamn+UilxN+21AAAAAIzPyUqnD7hflbVu5cgN97lteyU2WgEAhiEpAmBCcu2xugeMPjiX0eHzGfWmyYSgQAa6PymJj891h7Mn7nFL4dnxBQAAAGAsvR3Sh7+QDu91kyO3POAmSoxDLAEAkERSBMA4clUhjpE+upjVhx+ndbbT8XhViJzUGantjPTha9KNn5Fu+qwUKyGgAQAAQKgYY2Qkacjesyu3ocVsKh4mzMlKx9+Wku9I19dLt35OmjaL5AgAgKQIgJFys0I6+ow+OJfWkfMZDWS9XhUib6BH+uBn0pF90o3LpJuXSyXl7nWUwwMAAMCHHGNkjHu4ao9yzJrOGvVnjHrTRj0DRhnHvb1jJGPcpEjuv+uvLy3+DxAGxkinWt2v2Yvd5EjdPIayA0CEkRQBMCiXDDnVkdWBM2mdSVEVAh/K9EuHfum21lp4j7TofnoFAwAAwBPmctLDvlzB4RijgYzUlzHqHXCTHX2Xkx59ua+M+29v2kxqNiNJkTw494H7NfMG6ZbPSbNuYn4hAEQQSREAg7uXDp3P6L0zaaX6mBWCAMim3cTIR29e0SvYkBwBAABAXhnjJjBsS7IuH2t2Dzi62O3oUq+j9h7331SfG1vB5y585H7VXu8mR+beRnIEACKEpAgQUbl5Iems9P7ZtN4/m1ZfxuNFAVMx2Cv4XWneUrccvnoGvYIBAAAwJY5jpCHtrgYyRpd6HV3qufzV66ijx1Gawvrg6zgtvfWiO2tk0f3S/KVuzzLaagFAqJEUASImlwzpSxu1nk7rw48zynAwjzAwjnTyt9LJ/dLc26XFn5dqZtMrGAAAAONyjJEltwKkZ8DR6VRWl3octfcaXepx1Jum9CP0us5Lv/nv7gzDWz8nLbjLjS+oHAGAUCIpAkSIMUb9Gem3pwb0wbnMpPrXAsFhpDPvuV+zb5Fu/V13kCJttRAEQaxwCuKaAQCRZoxxiwEsS+ms0amOrE6nsjrdkVVnP0FSpPV2SL/9ofTRW9LSB4kjEGxBPE4P4poRSCRFgAgwxiidlVpPu22yqAxBZJw75H7Nv1O640tSWSUHWPA3y5be+YG7WzEIps2S7n4o73fb1tampqYmtba2asGCBZKkuro6rV+/XolEQi0tLUqlUlq9enXeH7sQksmknnjiCSWTSSUSCe3atWvwulQqpbVr16qxsVHr16/3cJXXpqWlRVu3blUymdTy5cu1bds2r5cEAMM4jpFtW3KM0cedjk51ZHUqldXFbkekQTBCx2lp73+U5n9KWvIlqbSCOALBQ2whidgiiIoRW5AUAULMMUaOI7WdSevAmbTSWa9XBHjk5H7pzEF3GPvNv+NeRik8/KrrvJQ64/UqPLNlyxbt2bNHTz75pDZv3jzsuu3btyuRSOipp57Sk08+6dEKJy8XrKxbt04dHR3Druvo6FAymdT+/fuLtp4tW7Zo48aNeb3PhoYG7dq1S2vXrs3r/QLAVOWSIJLU3uvoZLtbDXKuM8smMUzcyd9KZw+6LbVu+qxbNUIcgSAhtiC2KLCgxhYkRYAQcoyRMdL7ZzNqPT2gfgaoA1J2QDr4qjuQvX6V21qL0lzAV3IHvS+//PKo169fv15btmxRKpUq5rLyJpFIjAhcEomEDh48WNR1JJPJgt13bW1twe4bAK4mlwgZyBgdv5QZbInVRzyEa5Hpl957+XIcsVqadRNxBBAAxBbFEdTYgqQIECK5AYGHz2f07ok0AwGB0fRclN74r25SpH6NVFlLj2DAB7Zv3662trYxg5acjRs3as+ePUVaVfg0Nzers7PT62UAQN44xsi2LGUco+TFrI5czOh0R5b5ici/rvPSr/+LNOc2d5NVRZw4AvApYoviCHJsQVIECAFjjCzL0sUeR78+NqAL3dSDA1d17pB0/v+SbvystPjzkhWTbHZ7AV5IJpPaunWrGhoalEgkrnr7VatWFWFV4ZNMJvXUU09p6dKlXi8FAK6JMebyv9KJjqyOXsjoRHtWWcIgz7V39eobL/xEddUV+qt1v5+32472vc81v6kLnb3u/3f36WJnr775lc/pnlvmTXn9E3L2oPTxYenm5dKtD0iyaKkF+AixRXEEPbYgKQIEnGOM0hnpzWS/Dp+nLhyYFCcrHWlxZ47cscIdyE4pPFB0O3fulOT2jp2IBx98cNQy7e3btw/+d3t7uxYuXKjGxsbBy9ra2vTUU08NDux7+umn1dTUpHg8rr1796qurk6bN29WKpVSU1OTJGn//v1KJBLD+uReOfjv4Ycf1t69eyVpcODhRPrqJpNJbdq0Sa2trSOGJOY0NTWpra1NNTU1kqT7779/xPOUTCa1c+dO1dXVqb29XZJGPH5zc7NeeuklSVJra6sef/xxSRqx1lQqpa1btyqRSKi9vV3JZFIbNmxQfX39iLVt37598OeNx+MTCjoB4FrkqkIudDv68OOMjl3MMDfRJ76x48c6cuaSlt06Ty+/e1gr71qUl9uOpr2rV9/53mv65lc+p7pplYOXf/+Xbbr3X/0H/eTpP5/0fU6ak5EOvebOHLnjS9L1dxBHAD5BbEFsMREkRYCAchwjy3Lnhvzm5ADBAHAt+juld/9eOv6OdNc/lipqCGiAIjpw4IAkTfjAt76+fsSB9Nq1a/XYY49p9erVg5dt2bJFjz/+uLZt2zb4fbmhhJ2dnWpqatL69eslSY2NjVq2bJlqampUV1c3eLkkLVu2bNhlQwf/7du3T/fff/+wg//HH39ca9euHTUQGSqRSGjHjh2jDknM3U8umBr6M+XWkLN9+/YRt7ny8VevXq3Vq1dr3bp1kjT4nAyVTCa1du1avfDCC4PP72iXSe7zvXz58mGP29LSotbWVi1fvnzcnxsAJiOXCOlLOzr0cUaHzmeU6qM3lt8MrfRoeq01b7cdzYu/bNNzzW9qw5r7hiVFvvxAveqqK/SNHT/WW8/8i0nf75T0dkhvf1+aeaP06X8sVUwjjgA8RmxBbDERvFMDAZMrFT/X5egf9vfqzeMkRIC8ufiR9PN/Lx17w+3H4NCDASiG3EF7PB6f0vdv2rRJtbW1w4IWyd3RtG/fPjU3Nw+7vKamRi0tLSNuv3TpUj3//POjXr579+4Rj1tbW6tEIjFsx5gkPf3002praxsMMq5mtICtqalJe/bs0ZNPPjns8j179gzufpPcYKGpqUktLS2Dl23YsEFtbW0jfu6r2bRpk5YvXz4sQEkkElq+fLm2bt06eNmWLVuUTCZH7BibaIsCAJgIxxg5xih5KatXDvbpe+/06u0TaRIi0M1zp0uS2rv6PF7JEBeOSb/4D9Ip92SsDH+ngFeILYgtJoKkCBAgjjHqz0g/+7BPP36/Tx0EBED+ZdPSgR9L+16QetvdMngABVVbWyvJLa+eiqamphHBRs6VB92SVFdXN2pJ9lil2olEYsy15dY+VDwe16pVq/Tiiy9O5scYZuvWrVq1atWIYG7JkiV68MEHh63tyoAh9z2jtQEYSyqVUktLi+68884R191///1qbf1kJ++LL76oNWvWjHo/oz0fADBRxhgZY5TJGh04ndZ/e7dXPz/Ur5MdWRH5IGflXYt0qel/HXV2SHt3n+67db4Hq5KU6Zfe/YFbgZ5Nu616ARQdscVIxBYj0T4LCIDcIPVjF7J6/aN+DXBsBRTepRPSL56VFv+uO0TRGAaxAwWyZMkStbS0TOpAO9dvtq2tTdLYB8x1dXWj3u9Yt8/XgXcikdCePXuUSqUmvUstlUoplUqNujPqytL0XJl87vuSyeTgz5vrATwRucAkmUwO9jweKrerLJlMjrk2AJiqXDV8f0Y6cCatg+fSVMNj0r77/dckSd/48gPeLuTkfuliUrp7rVQ3T7Isb9cDRAyxxXDEFqMjKQL4nGOMBjJSy9E+nWgnMgCKyslI778inX5PuvuPparp9AgGCuDhhx/W888/r5aWlmH9dsfS3Nw8eOA8Wr/ciRgrmJhqmX0+5X6murq6Cd2+ublZTU1Ngzu9Vq9ePeGfIxdY5QK2hoaGMXfGAUC+5eaFdA0YtZ5K6/D5jBxKQjAF7V29erb5TX3v3zTq5rkzvF6OW3G+b4d0y+elWz8nyRBHAEVCbDEcscXoSIoAPpWrDjl6IaM3PhqgOgTwUscp6bXt0pLflxbe41aNsOMLyJtEIqEnn3xSW7duHdylNZ79+/cPHlwvXbpU0tjl3O3t7Z7sPDpw4IDi8fiUAqHceieyu62pqUlbt27Vrl27pvRztra2KpFIDBt+mK+1AcBYcsmQSz2O9p9KK3mJ9liYvPauXj3X/KYOn7mki529+snTf+6PhEiOMdKHP5fOH5bu/icMYQeKhNhiOGKL0fFuDPiQY4z6MkavHOzT3iMkRABfyKal/T+S3vq+lB2gRzCQZ+vXr1d9fb2eeOKJcW/X1tY2rDdtrsfuaMMKJXd44ER2iE3VaLvJcj10H3vssSnf76pVq4YNOBxqaAn61q1btWbNmhFBy9A+xdu3bx/875qamhG3y+3kevTRR0ctb5fcQYk5jz766Jhr6+joUGdn56jXAYBzuU3WmVRWP36vVz9q69NxEiKYorpplfrXX/6cnv3aH2nDmvu04W/+Qd//ZZvXyxrp0gmGsANFRmwxHLHFSCRFAB/J9dI9cj6jv/9tr052cNIV8J0z77mzRjpOE9AAebZr1y4tX75cK1euVHNz84jrm5ub1dLSMqIE++mnn1YqlRpx0L1p0yY1NDSosbFx2OXt7e2jDjcc7/KxJJPJEQfx3/rWt9TQ0DBqwDTWUMUrL3/66aclSVu2bBl2eVtb27DexLW1tSN2VjU3N6uhoWHUAOLKwYbJZHJwx9nGjRsVj8eHBTq5+xv6nOdud+XvqKmpSclkcsptBwCEl3N5gPpHF7P6YWuvXj7YrzOdjtfLQoisvGuRvvdvGvWVf9uk55rf9Ho5IzGEHSg6YotPEFuMZBnDGR3ADxxjlHWkliP9+ugSB0h+N7Pa1h/UV+bnzpyslHxHah19JwJ8yrI+6RHMEHZcRV9fn44ePaqbbrpJFRUV49/4nR9IXeeLs7BrNW2WdPdDeb/btrY2Pfvss+rs7FRNTc3gTqUHH3xwsBR7NLmD/NwAxPr6+mFBSzKZ1JYtW7Rv3z6lUimtWrVKDz/8sBKJxIQuzwVBuYP4devWSXJ3og0dRHgtj7thw4ZhP+OWLVvU2dmpRCKheDyuRCKhhoaGwetTqZS+9a1vqbOzc/Dy3Po2bdqkJUuWaMOGDcNK7bds2aIDBw6ooaFB9fX1w+7vyudR0uDtRnu+c7dpb2/Xgw8+qK1btw6WzX/7298e9/eVM6nXB4BAcYyRJenQ+Yz2n0qrq5/TD9fizz5TPfoVPosn7n3i3+u+W+fr2a/9UV5vOxFf+U6Tvr+3TZd2flN10/IUr+VbZR1D2HFNiC0mh9iC2GI0JEUAHzDG6GKPo58f6idQCAiSIhg0Y6F0z5el0grJjnm9GvjUhAMX4wSv13QQ15wnucBlx44dHq8k2EiKAOGTm494rjOr1z8a0MUeqkLygaTI1X33+6/pGy/8RN/7N4368gNXP3nmGcuSbv3dTzZYkRzBJBBbhBOxRX5M9PURzb8ywCdyOcn3zma0+0AfCREgiC4el157Tuo44x7AAdciiAFAENcMACgYY4x60kY//7BPze/1kRBB3k1v/Et95Tuj96nPVYccOXOxmEuaPGOkD34mvfU9N6nl8DpBAQTxOD2Ia0Yg8ZcGeMQxRums9OoHfXrz+IAc8iFAcPV3Sb/6W+n4O+7/U4QJAAAixm0HbPTuybT+/je9tARGQbR39aq9u2/M6w+fdpMhN8+dUawlXZsz70stO6R0D4kRACiiEq8XAESRMUYXuh394lC/ugc4eQqEgpOVWl9yB7AvXSMZizkjQMgxUBwA3GSIbVk6diGrt5ID6k0T36Bw6qZV6rHV943Zbuvldw+rrrrC362zrpQ6I722XbqvUaqdy055IKKILYqLd1qgiHLtstpOp9X8Xh8JESCMku9I+/728m4vdkgCYdTW1qbHH39cbW1tg//d0tLi9bIAoKhysc2lHkcvtfXql0f6SYhAktTe3aeLnb15ue1XvtOkRY/+u2GXfePLD2jD3/yD2ruGf99zzW/q7cOn9cr/55FJr9lz/V1uDHH6gNcrAVBkxBbeoFIEKBLHGBkj7T3cp2MXOVEKhFr7SXfOyL1flermsdsLCJn6+npt27bN62UAgGeMMerPGL15fEBHLmS8Xg584Lvff01vfHhKR85c1JEzl3TkzCV96VsvqK66Uo2fWzqscmMyt5Wkuurhg3JvnjtDz37tj/SNHT+W9EliZUZNpS7t/ObgXJHAcTLS+69Kc26TrBhV50BEEFt4g6QIUATO5aDh1Q/6daGbPqFAJPR3S7/6z9Kn/kiav9Tr1QAAAFyz3EavttNptZ5OK0Nog8v+9Zc/V5Dbfu+bjWNe91frfn/C9xMIJeXSZ/6Zu6GKhAgAFBRJEaDAHGN0qcfRqx9QTg5EjpOV3v2B1H1RWvx5dwC7ZXm9KgAAgEkzxuh8l6NfHulXVz9xDZBXli3d+xWpagYJEQAoApIiQIF9dDGrliP9yhI3ANH14c+lnkvSp//R5cQIgU5U5fqvA/gErwvA35zLr9F3kmkdOJMWr1igAJaukWbeyAYqTArHUMBIE31dkBQBCsAYI8uy9E5yQPtPp71eDgA/OPlbd4DifV+VLLEDLGLsy7/vbJaZUsCVcq8Lm/dFwHeMMersM/rFoX5d6qVXFlAQNy+XFt7j9SoQIMQWwNgmGlsQeQB55hgjx0g/+7CPhAiA4c4fkVpekNK9bmstREZpaalKS0vV1dXl9VIA3+ns7Bx8jQDwh1x1yHtnM/ofrb0kRIBCmXuHdMdKr1eBgCG2AMY20diCpAiQR44xymSl5vf6dPwSJzwBjCJ1Rtr7n9yqERIjkWFZlmpqatTR0aHe3l6vlwP4Rm9vr1KplGpqamTRMgTwBccY9aWNfvx+r948PiCH7ixAYdTNk+7+Y7e9LjAJxBbA6CYTW9A+C8iTT4KHPqX6OKgBMI7edmnvDmn5n0qVdZId83pFKIJZs2apt7dXx48fVzweV01NjWKxGCeCETnGGGWzWXV2diqVSqm8vFyzZs3yellA5OVaAH90MatfH+vXAHs3gMKprJOW/VNJNnNEMCXEFoBrqrEFSREgDxxj1NVv9JP3+9Q9QEIEwAT0d7qttH7nT6XqWcwYiYBYLKZEIqHz58+rs7NT7e3tXi8J8FRpaanq6uo0a9YsxWIkhwEvOcYo60j7jvbp2EWyIUBBlZRLn/ln7r/EAJgiYgtguMnGFiRFgGvkGKP2Hkc/Odin/ozXqwEQKAM90r6/lT7z/5DicwmKIiAWi2nOnDmaPXu20um0HIce7Ygm27ZVWlrKbkbAJ851OvrlkX71sMELKCzLlu79qlQ1nWN/XDNiC8A1ldiCpAhwDYwxOtfp6NUP+pThswfAVKT7pF//nbTsn0nT57uBEkLPsiyVlZV5vQwAQIQ5xsgY6e3kgN47y+4uoCiWPijNvIGWWcgrYgtg8jjzAkyRMUbJ9qxePkhCBMA1ygxIv/4v0oWPJMMbCgAAKKzcPMTdB/pIiADFsqhBWng3CREA8AGSIsAUGGN0+HxGP/+wXw4V5gDywclIb/xXEiMAAKCgjDH6uMvR/2jt1cUejjmAorh+iXT7Cq9XAQC4jKQIMEm5hEjL0QGRD4mmihKppjzPu3vKqqXKWslm0GykOVnpzSap/aREP1gAAJBHxrjRy8FzGf34feYhAkVTN1+6648lwxkEAPALZooAk2CM0bELWe07OuD1UlAglaWWplfZqiqzVFVqqbLUUmWZpeoyS1VllspLLNn5Lne2Y9L1d7hfkjtjor9L6ktJfZ1SX5fUf/nf7gtS18ccUIdZNi29/l+l3/lTqWYOAxgBAMA1cy4fO/7qaL8+/JhsCFA0lXXSsn/qtsyibRYA+AZJEWCCjDE6fimrXx7pp0IkJCpLLc2stge/ZlXHVFH6yYGq4xgZSbblDi4rmtIK92vaLLdyQHKHb+fW4GSk1Dm3mqDjtPtFoiRcMv3Sr/9vafkjUvV0KogAAMCUOcYonZF++mGfznVRiQoUTUmF9Nl/JpWUufEcAMA3SIoAE2CM0Yn2rH5xmIRIUI2XAHGMkaWRiQ/b9sFOntFOhtslUt08KT7nk2QJiZLwSfdKv/7PbmKE1moAAGAKHGPU2Wf08sE+dQ9wXAgUjWVL931Fqpw+ZuV3rqVdUTfgAQAkkRQBrsoxRqc7svr5oX7OLwdIeYk0v7ZEiekxzakZkgBxzOXK5U8OPPPeDqtYhp4kHytR0nFGOvehdPYDqfOcd2vF1PR3S7/6O6lhnVReTWIEAABMmDFGZzsd/ezDPqWzXq8GiJg7/0CaccO4LbMsy5IxRsYYEiMAUGSWMZzmBcbiXA4kXj3YpyyvFN+rqbCUqItp4fQSXTfNlmVZcowJbtIjH4yRZNxESW9KOvO+myC5+JFkaJ8QGFUzpAf+OaX3AABgwj48l9avPhpgY1eAlMY0bK5hVamtilJLsct7nm6bXTr6NxpH6rrgHuM7jtuKtb/LnU849F+O/4tj0f3S7V8c9ybGGLWdTutsl6Pfu6VclhXgzXoAEEAkRYAxOMbo4y5HrxzsU4ZjR1+yJF03zdaC6THdML1ENRU2JchX42TdaoPMwCcVJOcOSZk+r1eGq5m+QPqdPxs+XwYAAGCI3I7zt5MDaj2d9no5GMK2pLpKW3WV9uWEh5v8qCqzVF1mXU5+DD/Gc4wZltS68vpBuY1QuX9ljX7MmO5zkyO9HVJfl9R/OVnS0yGlzkh9qXz+yNF0/RLpnn8y7k0cY5S85HajkKSZ1bZW3lah0hiJEQAoFpIiwCgcY5TqM9p9oJdSc58psaV5tTElpseUqCtRWQnVIFOWS5AYR7qYlM4edJMkPZe8XhnGMvcO6d4ve70KAADgQ7kT6HuP9OvYRYIYL+USIDOrbc2otnVdtZsMyc0szP2uPKsOMOaTqpGhyZOBHqn91CczCjtOuVUmmJgJbGJyjNHFbkd73hvejWJauaUv3V6h6jKL2BYAioCkCHAFxxj1pY1+1Nan3jQvD7+YXmlr8ZwSLZpVohLbkuMYfwxCD4uhQdHF49KxN9xWW5TY+8/NvyPd8SWvVwEAAHwkd5L9lYN9OtPJ8VsxjZcAMZd/L4GKW4zjJk1ys+yGJUou/0uiZKSq6Zfb3ZaP2e7WMUa9A0Y/autVX2bk9eUl0orFFZpRbZMYAYACIykCDOEYo6wjvdTWq44+Xhpesy3phhkx3T6nVNdNi1ERUiyOI9m2O+T7+FvS8bcJfPymfrV0w3200QIAACREPFBdZmnB5VmGc2oCnACZqCsTJf3dn1SZnz8qOaOc4Y+Skgo3IVJZ+8lzdIWJnmuI2dLv3lKu+bUxWkIDQAGRFAEuyx3E/vj9Pp3rIpjwUnWZpcWzS7R4dqnKaY/lrVylyNkPpGNvSheOerseuCxLuq9Rum4Rg9cBAIiwXELk5YN9OktCpKBmVttK1MW0cEaJ6irdWYZGEZ4BkWvFm81IHx92kyTnDkkD3V6vrLgsW/rsn0jTE+7GslHk/lZePtinM6mrv05tS/rireWaWxuL7t8XABQYSRFgiF8c6qP/rofm1cZ0++wSza+LRTvA8KNc0NN9STr2unTitwxn91qsVLr/L6TqmWPuSAMAAOFFQqSwYpY0N+7OMlw4PaaKUluOMbIkdvBfyXE+qWDuOO224T37gdT1sbfrKoZP/ZG04M6rblRqOdKvQ+cnXlETs6Qv3lbhViLx9wYAeUdSBLjsnRMD2n8q7fUyIqcsJt1yXYlun1OqaeU2VSF+l/vIcLLSyf3SR29IqbPerinKKuukzz/mJkioGAEAIDJIiBRGiS3dMKNEC6fHNK82phizDCfPGEnGPTbt7ZBOvyedPiC1n/R6Zfl3ywPSbV+46s32nxrQOycmf64hZksrF1foOhIjAJB3JEUQecYYHTmf0d6jA14vJVJitnT7nFJ9al6pSi6fy2XHVcDkqkdOvycd/KnUfcHrFUXTdbdIyx5mvggAABFBQiT/4hWWbptdqluuK1GJLarW8ykXM6TOuRXnp1qlbAg2I86rl+5eO+5NjDH66FJWvzjUP+WHKbGllbdVaNY0EiMAkE8kRRBpjjG60O1oz3t9cnglFIUltzLkrgWlqiixSISEgZN1T8gn35U++IXUz1D2orv18+4XrycAAEKNhEj+WJaUqIvp9jmlmhuPUbFeaMaRZEnZATdu+Oit4G6qmp6QfudP3WqYMf5mcucafvxen7LXeK6hxJa+dHuFZlaTGAGAfCEpgshyjNFARvofrb3qTfMyKIaF02O6N1Gmmgp3MCEJkZBxHEmOdPR16dBeZo4U27J/Ks26ecwBjwAAINgcY+RcToicIyEyZZWllm69rkS3zSlRZSntez2Rqx65cEw69oY7pD0op6aqpksPPCqVlI3ZvtYxRr0DRj9s61X/xMeIjKs0Jv3+7RWaXkViBADygaQIIssxRj9+r0/nuggoCm1u3Na9iTLNrGYHViQYxy2JP/RLN0Hi5CkSwPhKKtz5IuU1JEYAAAgZEiLXbk6NrdvnlGrh9BjtsfzCcdzj1v4u6dibUvId97/9qrRCuv+fS5W1blJnFI4xyjrSS2296ujL7+m2spi06o4K1VaSGAGAa0VSBJH1+kf9ev8sJ2sLaUaVmwy5vpZkSCQZIw10Swd/Jp34zeWSeRRUfI50/19IVoxWWgAAhMRgQuR9NnRNxU0zY/r0vDLFK6kK8bVcrHD6PemDn/uvtZYdkz77J1Ld/DETIsYYGUk/eb9w7e3KS6RVd1QqXmHxtwwA14CkCCLHMUYfXczqtcNTH3aG8dWUW7p7QZlunFlC4BF1xrgn57svSu+/Kp15z+sVhd/8O6W7/tjrVQAAgDwwxihLQmRK5tfGdG+iVHVVMVr3Bolf5xV++h9L85eO2TIrZ++Rfh0+X9jNlxWXEyM1JEYAYMpIiiBSHGOU6jN6qa1XGWKKvLMk3TG3RHcvKJNlUZKOIYzjBhDnPpR++yP/BDdhVb9auuE+qkUAAAg4Y4xe+aBfpzqyXi8lMK6b5larz66hWj3Q/DSv8JbPSbf93lVv9tuTA3r3ZLrw65FUUWpp9R0VmlZOYgQApoKkCCLDGKOMI/2wtVed/fzZ51u8wtL9N5drVrXNLiyMzcm6M0Zam6WTv/V6NeFl2dLyR6TauWOW9wMAAP+j5e/E1VZaumdBmRLTqVYPFa/nFc5bKt390Lg3McbomAfdKCpLLT24pEKVZSRGAGCySIogUl79oE8n2tlllU/DqkMk2TYHY7iKXEstqkYKqyIu/e6/kGKlVIwAABAwxhgdPJfR6x8NeL0U36sus/Tp+aVaNKuEAeph5sW8wukJ6Xf+1N1wNMbflWOMLnQ72vNenxwPzq7VVlr6gyWVitlicyIATAJJEUSCMUbvnc3ozeMEFflEdQiuCVUjhZe4W/rUH3q9CgAAMAmOMTqbcvTywT4RrI+tvES6c16Zbp9dItG6NxqKOa+waob0wD+XYmWSPfocEccY9QwY/aitV/0eFnQtqIvpC7eWE5MDwCSQFEHo5eaI/LC115OdG2FEdQjyhqqRwvvsn0ozErTRAgAgABxj1NXvnmRNU+A+pltmlWjZDWWK2SRDIik3r/DSCek3/91NkuRTaaX0wKNSRc2Yx9COMcpkpZcO9CrV5/2JhqXXl+qeRJnXywCAwCApgtBzHKMftvWqvZc/9XygOgQFQdVI4VTWum207BLaaAEA4GO5k6w/bOtVFzMQR1VVZqnhpjLNqy2RMYZ4JOqcrCTjVo0cfd3972tlx9xNRXXzxkyIGGNkJP3k/T6d7SxCG68J+tyict0wI0aiEAAmgKQIQu/N4/06cIbhhNeK6hAUHFUjhXPDfdLSNV6vAgAAjCF3kvXH7/XpXJd/TrL6CdUhGJMxUvvJ/FSN3PXH0rx6txJlHL883K8jF/x1niFmSWuWVKiuyuY1AgBXQVIEoeUYo3Odjn78fp/XSwm80pj0+UXlmlcbYzcWCs/JSpkB6c0m6VLS69WEx/I/l+rm00YLAACf2nukX4fP++skqx9QHYIJyUfVyK2flxb/7lVv9puTA/rNyfTk778Iqkot/eHSSpWVkDwEgPGQFEEoGWOUcaT/vr9XPQP8iV+LmgpLKxZXaFq5xUEVise5vEOy9SUp+Y63awmLqunS5/8nKVbi9UoAAMAQxhi1nU7r7RP+PMnqJapDMGlTrRqZf6dbJTLuXRsdu5DVa0f6r22NBTar2tbqOypkWSKJCABjICmC0PrFoT4du8h0wmsxrzam372lnCAE3si10zr2unTgJ+5ARVybmz4r3fElZosAAOATjjE60Z7Vzz7090nWYqM6BNdkslUjMxZKn/0Tt2XWGH9rjjE63+V2onACcBbt5lkleuDmcq+XAQC+RVIEoeMYo48CsHvD7+6YW6L7EmUyIiECjxkjXTwuvfU9Kd3r9WoCzpIa1km1c2mjBQCAxxxj1NHraPeBPmXY+zGI6hDkzUSqRqpnSvf/hRQrk+zR54g4xqhnwOhHbb3qD1CHu3sTZVoyt4SkIgCMYvzJUUDAGGOUzki//oiEyFTZltRwU5mWLSyXZdEyCz5gWdL0hPS59dK067xeTcAZNygEAACecozRQMbo5YP9JEQui1nS524uV8PN5SohIYJ8sCyp9nrpc49Jc24beX1ppfSZfybFSsdNiGSy0k8O9gUqISJJbycHdLojK4e90AAwAkkRhIplWXr9eL8G6Jo1JZWlllbfUaFFs5g5AJ+xbal8mvTAP5fmLPZ6NcHWfUH64GfuzjkAAOAJ27L0i8P96k3zeSy5w6FXL6nQDTPdSlZ2tiNv7Jhkl0j3fVW65YHhly97WKqIj1lBnWus8uqHfersC95r1Uj6+eF+dfUbEiMAcAWSIggNxxid7sjq6AUyIlMxs9rWH9ZXaEa1TRACfxoMaBqHBzSYvCP7pNSZy/2WAQBAMeUGq59JUSIiuUOh/3BppaZX2VSHoDByf1e3fUG655+4lSGf/iOpbt6YFSLut1nae6Rf5zqD+1pNZ6VXPuiT43yS5AEAMFMEIZJ1jP77/l519fMnPVk3zYyp4aZyWRZl6giQU23Sb/5BcgJWx+4XNbOlBx5ltggAAEXkGKNUn9EPW3sDMay50G6eVaKGG8sk4hAUi3GkgR63Cv0qfnNyQL85mS7CogrvllklamDwOgAMolIEoWCM0W9OpkmITEH93FJ9blGFbAIRBM31d0jL/1wq4eB+SjrPSR++RhstAACKyUi/ONQX+YSIJXcI9AM3szELRWbZV02IGGN05HwmNAkRSTp0PqMT7RnaaAHAZSRFEHi53VYHzoTngKVYPjWvVPcuLJNE314EkGVL8bnS8j9zhyRi8g7vlfpSJEYAACiSt5IDau+N9uduWUxacVu5lsx15xgSh8BPHGP0cZejlqP9Xi8l71qODiiTpY0WAEgkRRACtmVp39H+yO+2mqy7F5TqrgVlXi8DuDa2LU2b7VaMlFV7vZrgMY70/quf9FkGAAAF4RijM6ms3jsb7baf8QpLf1BfqbnxGMkQ+I5jjLr7jX76YTirufrSRvuO9vPaAwCRFEHAOcbog3NpnesK7uAzL9y3sEx3ziMhgpCwbal6htTw51J5jderCZ5TrW4rLYf3UQAACsEYo0xW+uXh8O08n4x5tTH9QX2lqsss2mXBd3Kv05cP9qk/xLnLjy5ldfQCbbQAgKQIAit30PJ2csDrpQTKZ28o05K5pV4vA8gvOyZV1kkNj0gVca9XEzzvvewmlwAAQN5Zlyvbe9LRPQl5w4yYvri4XCW2ZNskROBP/RmjgWz4X6e/PtavgYwhMQIg0jgDgkB79+SABrJeryI4li0s021zSIggpOyYVFHjzhi5yvBEXOHjw9KFjySHN1QAAPLJMUaHz6f10aXofsbePLNEn19ULkvMD4F/WZal6nJLq++oVGVpuP9OB7LSL48MULEFINJIiiCQjDHqGjD64FyI61rz7N5Eqe6gQgRhZ8fcSpHf+TOprMrr1QTLey+7zx8AAMgLxxj1Dhi9fiy6le23Xlei+2922/aSEIHf2ZalmgpLq++oUFVZuP9eT3VkdfBcmmoRAJFFUgSBZFmW3jo+EMrhZ4Xw6fmlqr+eGSKICDsmVdVJv/OnUmmF16sJjo5T0un3qBYBACBPLEmvHe5XOqJju26bXaLlN5VLIiGC4LAvV4ysuaNC00KeGHnr+IB6BmijBSCaSIogcBxj9HFXVscjXII+GUuvL9Wn55MQQcTYMal6lvTZP5VKyr1eTXAcfFXipAUAANfMGKP9p9M61xXNjMjtc0r02RtJiCCYbMtSZZml1UsqVB3ixEjGkX55uF/h/QkBYGwkRRA4tmXpjY+iW4I+GYuvK9E9CRIiiCjblmpmS5/5p7SFmqjui9LxdyQnmidwAADIB8cYtfc6+u3JtNdL8cSt15XoMzewKQXBZluWKkovt9IK8YyRc12O2s6kZagWARAxJEUQKI4xOnYxo/PdnLC7mjk1tj5zIwkRRJxtS3Xzpfo1Xq8kOD78hWR4jwUAYKpsy9KvjkWz1e/Ns0r0OzeWcYIVoZCrGFl1R4UqQpwYefdEWqk+2mgBiBaSIgict5NUiVzNtDJLX7iVWQqAJMmypYV3Szcu83olwdDfJR39FYkRAACmwDFGhz5O6+MIts26cUZM99/EUHWES27GyKrbK1Re4vVqCsMx7vwjXrUAooSkCALDMUbvn82oq5/dC+MpsaUv3lahkph7AAfgsiW/L828yetVBMPhFikzILFbDACACTPGKOtEcxPXgrqYPreIGSIIJ9uyVFNh6fdvr1BpSLvyXuxx9OHHGapFAEQGSREEhjHS/lPRCzAm64FF5YpXWCREgNHc+2WparrXq/C/TL/bRgsAAEzK28kB9WW8XkVxTa+09flbSIgg3GzLUm2lrc8vKg9tRcU7JwaUdUT7OwCRQFIEgZCrEumPWIAxWZ+eX6pEXYyECDAay5ZipdKyh6US5u1c1UdvSv2dVIsAADABueHqH5yLVsBSXiJ98bZy2RYJEYSfbVmaVxvT3QtKvV5KQfRn3MQIAEQBSREEgjHSgTNpr5fhazdMj+nT88sIRoDx2DGpeoZ091optHu88sTJSgd/JvGeAgDAVeWGq0dpK4FtSb93a4UqS6lSR3RYlqWl88p008xw9tE6eC7D0HUAkUBSBL7nGKMPP86oN82H8lhmVNl6YFE5Za7ARFi2dN0t0m2/5/VK/O9UqzTQ4/UqAADwNccYHTmfidxw9c/cUKbZ02wSIogcY4wabirXzOrwnVIzRnr9o35e1wBCL3zv4AilttNUiYylokT64uJyWZSsAxNnWdItD0jz6r1eib85WbeNlonWSR4AACbDGOntiLWcuW12iRbPLiX+QCRZliXLcuPwytLwvQZOpxwdv8TQdQDhRlIEvuYYo8MfZ9Q9wIfxaHIl6xWUrAOTZ4z06T+S4nO9Xom/ffSW1ysAAMC3jDFqO51WT4TilTk1tpbdwHw2RJttWSovsfSFxe5MnbB563i0Er0AooekCHzNkrSfKpEx3ZMo03WUrANTY1mS7MuD18u9Xo1/9XdJp99zq0YAAMAgY4z6M1JrhOKVaWWWvnBrhdfLAHzBtizNrLK1/KbwJQk7+40+OEe1CIDwIikC33KM0ZELGXX18yE8mtk1tpbMpWQduCa2LZVXS3d8yeuV+Nux190h9QAAYJBlWXr7xIAyEekyWWJLX7ytQiUxsSkLuMyyLC2aVaolc0u8Xkre/fbkgJyIvL8BiB6SIvAtS9L+U9HZdTUZJbb0wM3l7NoA8sGypYV3S9ct8nol/nXphJQ6w2wRAAAuc4xRe6+jwx9nvF5K0TywqFzxCtr2AqO5N1GmebXh2kTUl3E7dxjOOwAIIZIi8CXHGJ3syCrVx4fvaO5eUKbqMgISIG+MI33qH9FGazxHf+0mkAAAgGzL0hsf9Ssq0Ur93FIl6mLEH8A4fveWclWFbPD6e2fS6s8YEiMAQoezG/Al27L0/tno7LqajNk1tu6gbRaQX9blNlpLaKM1plNtUrrX61UAAOA5xxid68zqdCoaFZS1FZbuXkD8AYzHsizFbIVuvkjGkd45keb1DyB0SIrAd4wx6ux3dKqDob5Xom0WUECWLSVoozUmJyt99BYttAAAkWdbVmTa/Fpy22aJ86HAVdmWpfl1JbplVrjmixz6OKNUn0O1CIBQISkCX3r/TDSCjMm6e0GZqmibBRSOcaRP/RFttMby0ZterwAAAE+Zy7NETkZkA9eS60s1o8om/gAmyBijZTeUhaqNlpH025NUiwAIF5Ii8B3HSIfO0zrrSrm2WQQkQAFZtlReRRutsfR1Smfed6tGAACIIMuytP/UgNfLKIraCkt3z6dtFjAZYW2jdexiRr0DVIsACA+SIvAVxxgdOp9RmvNtw9A2Cygi2miN7+jrkh3zehUAABSdMUbd/Y6OXQh/sELbLGDqwthGyzFSGx09AIQISRH4im1ZOniWD9or0TYLKDLaaI3tUlLqPMdsEQBAJLWeTisK25TqaZsFXJPBNlpl4XkNffhxRllCAAAhQVIEvuEYo7OdWbX3RiHMmLjZ02ibBRTdYBut3/d6Jf505Fdi6ygAIGoGsu7A4bCrrbB0F22zgGsy2EbrxvC00UpnpYPnMnSwABAKJEXgG7ZlMWB9FJ+9sYyDDsALli0l7pJqr/d6Jf5zqk3K9Hu9CgAAisYYo7bTaWVDflhO2ywgf8LYRus9OnsACAmSIvCNgYxRsj38/Xkn46aZMU2vilElAnjFyUq3r/B6Ff7jZNzECAPXAQARkXWkg+fCfzKQtllAfoWtjVbPgNGxC1k2bgIIPJIi8AXHGB25kJHD5+og25LuWVAmw8EG4B07Js26yf3CcKffY+A6ACASHGP0/rm00iHfC1BD2ywg73JttH4nRG202s6kSZwCCDySIvAF27J05EL4+/NOxq3XlaiqzCIoAbzmONIdK71ehf9cPCale71eBQAAhWek986EP1a5e0EZbbOAArAtSwvqSjSnJhyn4C71ODqdoloEQLCF4x0ZgWaMUVe/o/NdjtdL8Y0SW7prfnh2kgCBZttSfK50/RKvV+IvxkinDtBCCwAQao4xOnQ+o950uE/+zay2deOMEnZ/AwXiGKN7E+GJ8dtOUy0CINhIisBzRtLh8+HfeTUZd8wtVVmJqBIB/MI47mwRi4/NYWihBQAIOUvuyb+wuydRJodexkDB2JalWdNiStSF49j5VEdW7b0O7b4BBBZnd+A527J0hKTIoPIS6c7r6eUL+IplS5W1UuIur1fiL7TQAgCEmOMYHb+UVWd/uE/6XR+3dX08Jtsm/gAKKVctEpZXWuvpNOctAAQWSRF4yhij813hDzQm4855ZbJ5ZQL+tPj3JLvE61X4By20AAAhZtuW3j8b/iqRexNlzAYAisC2LMUrbS2aFY544tiFjHrTVIsACCZOvcJztM76RHWZpdtn08sX8CXLksqqpJs+4/VK/IUWWgCAkOoZcHS2M9xzD2+YHtOM6hjxB1AkxhjdtaBUYSjMcox04DTncwAEE0kReMpIOnaRD9GcT88vVWhqaYEwsizplgek0gqvV+IftNACAIRQbsB6mFnW5Vki7PIGisayLFWWWrp9TjiqRQ6dT4t3EABBRFIEnnGM0ZmOrPrDHWtMWF2lpUWzqBIBfC9WKi263+tV+ActtAAAIRSFuYe3zCrRtHKL+APwwKfmlak0BMXW/RnpdEeW5CqAwCEpAs9Ykj66xEm0nDvnlbHDAggCy3ZbaFEt8glaaAEAQsQYowvdWaX6wnt0HrOluxeUer0MIJIsy1JJTKqfG47X4JELGZKrAAKHpAg8Y1mWTrSTFJGkilJLN8ygly8QGFZMWvBpr1fhHxePSek+r1cBAEDeHPo43FUid8wpVXmJJYv4A/CEbVmqv75UlaXBfw0mL2WVdcKbRAYQTiRF4AljjM53ZdWb5oNTkm6dFY5+okCk3MjA9UHGSOcO0UILABAKYZ97WGJLd84rJSECeMyypPrrg18tknGk45eyckiMAAgQkiLwhJH7oQm3jdhtc0qYrw4EiWVJVXXSrJu9Xol/nD/sthYDACDAHMfoZHu45x7eOLNEJXxkA56zLUu3XheO1+ORCxnZNmc1AARHCN56EUS2ZelEe4gjjUlYUBdTVZnNTi0gaJysdMN9Xq/CPz4+4iaLAAAIMNu2dDjkA9bvmEOVOuAXJbZ044zgvyZPd2Q1kKFSBEBwkBSBJ3oGHLX38oEpuVUijuG5AALHjklzFksVca9X4g/9XVLnx16vAgCAazKQMaGeezir2tb0qhgbsgAfuWNu8JMijpGOXshwbgNAYJAUQdE5jlGS1lmSpJpyS/NqSxiwDgSWkRbe4/Ui/OPch8wVAQAEluOYyyf1vF5J4bAhC/AXy7I0vSqmWdXBPz139EKGcxsAAiP477oIHNu2dKKDk2aStHh2KUEJEGSWLd1wL7M0cs4fcStoAAAIoLC3ziovkW6awYYswG8cx+i2ELS1O9flqGfA8XoZADAhnMVB0WUdozMpkiIxW7r1OoISIPDKqqS5d3i9Cn+4eFzKhvdkEgAgvIwx6uxzdL47vCf0bplVyvgvwIds29KNM0pUHvy8iI6cp4UWgGAgKYKiMsbofLejbHhjjQm7cUaJStlQDQSf40g3LvN6Ff7gZN3EiOFNHgAQLEbSoRBXiViSbg/BTnQgrGzLTVwG3RFaaAEICJIiKCojUSVy2e1zSsT+CSAEbFuakZBqZnu9En+4+JF4cwMABI1tWTp6IbxJkXm1MVWX2wxYB3wsDInL9l6jjl5HhmoRAD5HUgRFZVuWznWSFJlZbWtmdYwdFEBYOFl3tgikS0k3UQQAQIB09Tvq6g/vSbzb5pTICfMEeSDgLMtSdbmtebXBbydx+HyGPVIAfI+zFigqxxh93EVblZtmEpQAoWLHpHlLRaNuSe2naJ8FAAgUxzE60R7ejVvTyizNr43JtjlOAfzMMSYU1SLHLtJCC4D/kRRB0RhjdLHbUYZzZbphOkEJEDqlFdL0hNer8F42LXWe83oVAABMmG1bOt0R3qTIrbNp2wsEgW25CczqsmCfK+jqN+rq58QPAH8jKYKiMYZ5IpJUW+mWxQIIGScrzVns9Sr84cJx9/kAACAAjDE6E+IWvzfNLGHXNhAgienBb6F1qiNLdwwAvsaZWRSNbVs628lugURdiRyGjgHhY8ekuXd4vQp/uHTCfT4AAPA5Y4zOdztKhzQnEq+wNI0NWUBgGEkLpwe/hdaZVJbuGAB8jaMjFI0xRue6QhptTMLC6TFxaACEVFWdVD3T61V471LS6xUAADAhRu6O5rBK1JXIsCELCAzbsjS7xlZZwPcX0SUEgN+RFEHRXOoN7w6siaookWZW27IoXwfCyTi00JKkvpTU3+X1KgAAuCrbskKdFFk4I+BnVoEIsi1L82qD/drty0gdvXQKAeBfJEVQFFnH6Byts7SgLvhlsADGY0lzb/d6Ef7QfspNEgEA4GPprNs+K4zKS6RZbMgCAscxRokQtNBirggAPyMpgqKwLeliSIONyUhMj4lDAiDELEuqmy+VVXm9Eu+lzkq06wAA+JhjjM6ksqH9uJrPhiwgkGzL0oK6mIKez2SuCAA/IymCorAsSxd7op0UiVnSvNqY7KAf2QC4utm3eL0C76XOMmwdAOBrlsI+T4QNWUBQlcYszZkW7FN2ZzuzzDQC4FvBfodFYDjGqD3i/STn1sYUY5cEEH7MFXF1nvN6BQAAjMsK8TwR25Lm17EhCwgqxzFaEPAWWgNZ6VKPQ2IEgC+RFEFRpPqMot5KMlEXo58mEAV2TLruFqokui9K2YzXqwAAYEw9A446+8N5fD43HlMJG7KAwLJtSzdMD348cSrELQoBBBtJERSc4xhd6A7nDqzJWDg9Rj9NICpipdLMG71ehceM1PWx14sAAGBUjmN0sj28MQobsoDgqy63VVsZ7HMIZ1IO50EA+BJJERScZSny80TqKi1VlPJyAyLDyUqzbi7KQ333+6/p5XcPj7j8K99p0oa/+Qe9feiUJKm9q1cvv3tYX/lO0+Bl43n70Cl95TtNOnLm4tQX13HGfS4AAPAZ2w5v6yxJWjiDDVlA0DnGKFEX7BZa5zqzcigVAeBDwX53RSBYlqVL3dFOisyoDn7ZK4BJsGypbl7BH6a9q1ffeOEn+t6/aRx5XXevvr+3Tc81vzl4WV11hb73zUbdc8vV13bkzCV9f2+bvr+3bdzbHX7+X+nmuTNGv7LzrPtcAADgQ2c6w5kUqau0VMmGLCDwLEkL6mJqPZ32eilTlnGkC92OZlXbsphxBMBHSIqgKC5FfMj6rGpbjmPYrQVEhWVJtdcX/GGGJjyudM+iefrGlz83WBVy89wZ+vID9RO+7zc+PKnHVt+nRXOnj3r9hc7ewfsdU+d597kAAMBnegYc9Yd09NWs6piMMZyABALOsizNqLZlSQpyrcXpjqxmXv45AMAvSIqg4HpDHHBM1Kxqm4QIEDWxUql6ptR9oSB3//K7h7XyrkWSfjLmbVbetejybabm2a/90ZjXfWPHj/VX635//DvouYbWWwAAFIhjjM53hXfT1sxqW8awLwEIgxLbUrzCUkdfcNMiZzqz+pRV5vUyAGAYampRUMaYyFeJWJKmV/FSAyKpgNUibx86NaE2WFO17Nb5Y173XPOb2rDmvqvfSW+KmSIAAF+6EOKZh7OmsSELCJOZAW/HfTHi7dQB+BNnalFQjpE6A7yjIR9qKy3FCEqA6HGyBUuKPNf8pv71lz9XkPvOGavVVm7w+rhtswYZqbcjj6sCAODa2ZYV2pN0liXVVRLmA2GRdYxmVgf7NT2QdVsWAoCf0D4LBWVZUld/tJMiDFkHIqpAw9aPnLmoGdMqJ3zbl989Mvj/h09f1De/8jnVTfD7R/NX3//luG21Rui+IFVNp4cHAMBXwlopUldhsyELCBHbcqu/gu5ij6PKUotZRwB8g6QICsq2LHX2hzPgmCiGrAMRVaBh69//ZduEqkSOnLmktw+d1mOrP2lz9fahU7r3X/0HvfV//k9TSow81/ymNqyeQNusoXraJeNIFgliAIA/9KWN+tLh3LjlzhNhyDoQFpZlaXpV8IetX+xxNC8eY58UAN8IfroZvhf1ShGGrAMRlhu2niff/2XbmG2trvS9bzaOuO09t8zTPYvmaf1f/8OUHv97v2yd/ByTnnaqRAAAvmGM0YXu8M67mllty4l2+AWETm7YepC19zicFwHgKyRFUHBRrhRhyDqAfFWLtHf16mJX7wRneYztS3cv0vf3tk36+55rflP3LJpCO7DedreVGAAAPmCMdCmkrbMkt80O7bOA8An6sPUwv+8CCCbOUqCgBjJG6fBuxLoqhqwDEZfHYevPNb85rBXWVOXmkbx96NSkvu/Z3W/oS3cvmvwDMmgdAOAjtm2pvTecpRQMWQfCKesYzQj4sPVUn1GWMjYAPhLsd1X4XpSrRCSGrAORl6dh628fOjWptlUb/uYf9I0dPx71urppFZKki129E76/I2cu6u3Dp3Xz3OkT/p5B/d2T/x4AAAqovTecMQpD1oFwsi3puoAPWzdyEyMA4BcMWkfBOMZE/kNvZpWtrGMIToCoytOw9SNnLqnptVY9u/vNYZe3d7uJje987xdqeq1VM2oq9ezX/kgvvtaqlXeNXtVx5MwlSdJ9k0iyvPzuEUmaWuuuAZIiAAB/SfWFMynCkHUgnMIybL2911FtpSWb9ygAPkBSBAVjjNQV8UqRaeWWyIcAERcrlUorpfTEKzOu9OUH6kcdsN7e1avpD39H3/zK54dd/9jq+/RX635/1Pv6yTuHdfPc6aq73EZrIt6aZKutYZyslBmQSsqmfh8AAORJ94CjTEhDlOlV7pD1GPEHEDoltqVpFZY6A7zxNNXnSCbmDl8FAI8Fu/4OvmZbUm86uB/Y+VBdZrFTC4BUUVPUh1t26/xRZ4a0d/Xq+3vb9FePjJ4wGcuRMxdVV10x9QUN9Ez9ewEAyBNjjNpDPOy3qowNWUCYVZcG+wWe6nNk8yYFwCdIiqBgLMtSfybaSZHKMl5iACSVTyvI3eZaYV05H+TLD9Tr2eY3RyRGVvy/X9Bjq+8bUXXyle80adGj/+6qjzNl/Z3X9v0AAOSBY8I7T0Ryq9TZkAWEV2VZsF/fHb3RPj8EwF9on4WC6kt7vQLvWJLKeYUBkKSK/CZF3j50St/53ms6cuaiJOkbO36sn7xzWF+6e5EeW32fJOnZr/2Rvvv919T0Wqvau/t0sbN3RJutocarBLln0bzB+SVT0tclGccdPA8AgEdsK9wn5SoDvoscwNgcY1RVakvKer2UKQvrPCcAwWQZY8J7VAjP/bC1VxdDXKI+nooS6av3VHu9DABec7LSBz+XDu/1eiXeWbpGStwt2TGvVwIAiLiXD/bpVEdwTyqO50+WVTHAGAiprGN08FxGbx4f8Hop1+Srd1epggQuAB9gyyYKqi/C7bOqaJ0FIKdA7bMCo7/b6xUAACApvDMPy0tEQgQIMcsKRzVYR4hbGAIIFs7aoqD6Qxp0TEQYDlgA5IFlFX3Quu9kBuQ2FQQAwFt9IY1PiD2AcLMtS9UBnykiSV0DRg4NawD4AEkRFEzGMcpG+LOusswS3ekAyLKlirjXq/BWdsBNDgEA4CFjTGiTIlSpA+FXFYKkSH/GiNMkAPyAIycUzECEW2dJ7m4tPuwBSKJSJJsmKQIA8NxAVgrr4TmVIkD4hWEWR3/aUD8OwBdIiqBgojxPRJKqSq3QBl0AJqm82usVeCsT7IGQAIBwCGuViOQmRRwnvD8fAKnEtlQa8LN4/RnDXikAvhDwt1P4WZiDjomoLLNk82EPQJLsmFRS4fUqvJNNe70CAADUMxDe+KSqjA1ZQBRUBryFVl/GyCIrAsAHSIqgIIwxyjher8Jb1WUWH/YAPlExzesVeCdLpQgAwFuOMeoN8aatylI2ZAFREPRWef0R7ygCwD9IiqBgnIgnRYJ+sAIgz8qjnBShUgQA4C1jwt3et4oNWUAkBH3YOkkRAH5BUgQFYSRlI/5ZZxOUABjKjnm9Au9kSIoAALxlWQp1pUhpjNgDiIKSgJeE9WW8XgEAuEiKoDCMW6IeZQE/VgGQb1aEP3JN1usVAAAizrasUM88JPQAws+Y4A8pp1IEgF9E+AwNCsmI9llBP1gBkGdRTooAAOADYa4UYUMWEA1Bf60bI6Wj3lYEgC9whgYFE/XPuaAfrADIsyi3z2L/KgDAB8JcKULsAYSfUTiOqqkWAeAHJEVQMI4T7Q+6MBysAMgjKkUAAPBUmCtFqFIHoiEMs0tJigDwA87QoGCiXikSgmMVAPlEUgQAAE/1hfhEXBhOlAK4ChOO8wy9aSMT8Rm0ALzHGRoUhCVmigAAAADwh6xjxDk4APBeX9qIt2MAXiMpgsKwFPkPOYIuAMOYCGeKw7ClDQAQaGE/NHcIPoDws8JxnqE/E46fA0CwkRRBYRiG/fEZD2CYKCdFAADwWsgPzjnBCERDGBKgA1nDDFYAniMpgoIwkuyI/3VFfM48gCtFOSnCPBUAAAoqwkcZQGRYCkd+l4QIAD/gLAUKJhbxdikh2MABIJ+crNcr8E5JmdcrAABEXNgPzZnnCERDGDZfWrRbB+ADJEVQMLGI/3WF4WAFQB5FuVKkpNzrFQAAEGqEHkD4WZYVis2X0d4+C8AvIn7aGoUU9ZkiYej1CSCPIl0pQlIEAIBCymSJPYAoyIRg92XEm4oA8AmSIigIyyIp0pcO/sEKgDzq7/Z6Bd4hKQIAQEF1DxgZNmUBodcbgvMMET9VBMAnSIqgYGIRz4oQmAAYpr/L6xV4p6Qs2u3DAACeC/tReW/a0L4XiIDegRC80KN9qgiAT5AUQUFYolKkJ21C0e8TQB44WSnd6/UqvFNSLt4QAQCeCvnHUO+AoSUNEAE9oagU4c0KgPdIiqAgLMuK/KD1UOzgAJAfAz1er8BbtM8CAKCgetNGNlkRINSyjlE6BGMKeasC4AcRP22NQiqLRfuTrjfNbi0Al/V1er0Cb5WSFAEAeCvs25XCsHscwPjCMreU0yQA/ICkCAqmvCTaH3U9aSOLrAgA40i9HV6vwlsl5SL8AQCgcKhSB8KvOySvc06TAPCDEq8XgPCqKJ3YJ93ffPNPVB2fri889M914+13qbuzXcfee0c//cF/1B/++ZO68fa7xv3+H/3dv9ONt92l+s98YUKP193Zrp/9/Q51dVyUJPV0tqs7dWlCjzUZBCYAJLmzNKI8ZF1ykyJEPwAAFExP2vF6CQAKyDFGPSE5x2CJ7VIAvEdSBAVTGpvY7Xq6OvTGq3+vn/39jsHLqmrq9LW//LurJim6O9v14t88pa/95d9N6LG6O9v1w7/9P/SHf/6/qLqmbvDyN175gf63P39A//qv/8eEkytX0xuS0lYAeUBShKQIAAAF1J9xT5oyVwQIJ2PC0yaPtykAfkBSBAVjW5bKYtLAVQaB3XDbXfqDP/2fdezgu5Kk2fNu1LIVD03oMYYmUibi9Zd36Wd/v0NfeOgvhiVFlq14SFU1dWr6m6e0+T//clL3OZa+tJExtNACIs+OMVOktNLrFQAAEHr9aaPKMmIPIIwsKzwbL3mXAuAHJEVQUBWllgayV//grv/MFyZdodH2+k9Vv2xy3zN7/k2SpJ7Owvf3N3J3bFWUFvyhAPhd1CtFKuNerwAAEHETrWIPsp60UWWZ16sAUAi2ZYWmRTf7RgH4AYPWUVAVBRy2fuzgu5OeAVL/mS/o3798YtTv6+ls10133J2fxV0Wlp0cAK5RlCtFSsql0gqvVwEAiLhcFXuYdQ+4leoAwqk3JLODLIaKAPABkiIoqPICJUV++oP/pD/40/9X3u7vR3/37yRJf/Bn/3Pe7lOSuvsdAhMA0a4UqZru9QoAAJDkVrGHWc+AkUPoAYRWWAatl8UsciIAPEf7LBSMMWbCgce5k0fV9vpPh/3/lcPQh143LZ6/k2zdne366Q/+k772l3832F4rX7ouByYxPvGB6MqmpYEer1fhneoZXq8AAABJbhV7SuE4qTiaSz2ObOIOIJSyjlGqLxzvX9VlFrNXAXiOpAgKxpiJVYp8fPKoPnr/XX3hob8YvOzY++/qf/vzz+l//9vXRiRG3nj176+5SqS7s10/+/sdOnfiiLpTl/Sv//of8p4QkaSL3Y7s2Xm/WwBBYYyUOuv1KrxVNV1ysu7AeQAAPBT2SpEL3Q4nGoGQutTjhCalW1lG0xoA3iMpgoIxkqrKrn5Q/rXv/JcRl914+1268bZPa8dffm3Y9W+88gMt++IfX/PaqmvqBhMrba//VC/828f1hT/+Cy1b8dA13/dQBCZAxBlHaj/p9Sq8RfssAIAPGGMK1trXL9p7HTmOkU25CBAqWcfofHc45olIUjlnIgH4AOlZFIxtSdMmkBQZS/1nvqg3Xv37wf/v7mxXV+pS3is66j/zBf3Lv/w7/c3/+qf66Q/+U17vu73PUZbGvkB02TGp44zXq/BW9QyqRAAAnjMm/JUijnETIwDCxbbcDZdhUF4i2WwcBeADJEVQMJZlqaZi6n9iubkhx95/V5L0s7/fMazFVj5V19Rp2Rf/WC/828fV3dmet/s1BCYAOk57vQJvTZvp9QoAAJCRO1Mk7M53u9UiAMLDsixd6M56vYy8qAx5chpAcJAUQUFVX6VSZMd3vq6mv3lq1OuqLs8S6U5d0rH339WNt92V59UNd9OSeyVJB4YMfM+H810EJkBkZTNS13mvV+EdOyaVVXu9CgAAZFnhrxSRcu17vV4FgHzKOkYdveE4p1DFPBEAPkEnPxRUScxSeYnUnxn9+tdf+YHql/3eqNedO3lUknTjHXfrwOs/1a9f/m/66Q/+47Db9HR1SJL+x9/+H/r1y/9N1fHpWvfNvx5zPf9i5QLVL/u9UeeYVE2rdR/31LGr/FSTc6Hb0WKGrQPRY4yUOiOFZiTiFFRNF2dmAAB+YFtWJHYoM9MQCJ8wDVmPQnIaQDCQFEHBTSu31Z8ZvYXU7/3xOjV+7dujXtf2+qu6bv5NbmurFQ+NOgS9u7Nd/8+VC/SP/vx/ueqQ9O7OdvWM0xorl4SZPe/Gce9nsghMgIhiyDpD1gEAvhKFpAjD1oFwCduQ9apSS44xzBUB4Dnq1lBw8YqxP+xuvuOewZkhQ3V3tuuNV/9ejf9yc97WUV1Tp9/743WjVolIUtvrP1XV5QRMPjFsHYgohqy7SRETniAOABBs5RGYKcKwdSBcwjRkXXKT04bTIwB8gKQICspxjOLjDFtftuIh/fQH/3FEYuSv/uUf6vf+eN1VExQfnzwmSepKXRpx3d9880/05No7h132B3/2P2vHd74+Ypj6T3/wn/TRwXf1jb/54biPNxUMWwciLOpD1qumi6gHAOAXZRHpk8CwdSA8wjRkXXKTIhSyAfCDiBwWwjOWVFM+fu5t3Tf/Wj/6u3+nX7/839TT2a7u1KWrtsM69v67+uHfbtW5y0mRF/+/m9T2+quq/8wX9YWH/mLwdrk5ITmz59+kdd/868Hh7rnHq45P1//18glVXx7unm/nuxzVVdqK8ekPREc2He0h65JUPUOy2H8BAPAH2xp/3mFYXOh2dOt1Xq8CQD6Eaci6JFWVWbQXB+ALljFs4URhXejO6kdtfV4vw1O3zCrR8pvK+PAHosIYd55Iyw6vV+Kt3/uaVM1cEQCAf/z33/aooy/cIfCMKlt/uLTS62UAuEbGGF3odvTSgfCcT1n76UpNu8rGWQAoBt6JUHC1lbaingpg2DoQMcaR2k95vQqPWVJl3OtFAAAwTHUETsZd7HHUlw534geIAiPpRHt4WmdJUkUp50UA+EP4jwjhuRLb0rRxhq1HQXuvo/4MgQkQGXZMOn/U61V4q3qG+zwAAOATxhjVRiQuSV7KMFcECDjbspQMUVKkxHbPDwGAH5AUQVHMrIr2n5oRgQkQKU5GOn/E61V4a0aCIesAAF9xjBSvjEZckmzPyubkIxBoPQOOLvU4Xi8jb6rLeU8C4B/ROCKEpxzHaEbEkyKSlLxEYAJEguNIHx9xEyNRNj3hthEDAMAnYral6RFJipxOZZVlQxYQWI5jdPxSeKpEJKkuIu+/AIKBdyQUnGVJM6r5UyMwASLCsqSzB71ehfdm3ED7LACA79RG5KRc1pFOd2TlULUJBJJtW6GbJ1JXadM9A4BvROOIEJ6yLEszqzkxlnGkMykCEyD0LEs696HXq/BWaaVUPd3rVQAAMEJ5iaWyiIQmx9uzok4dCKZM1uhMKlxJkemVtnhTAuAXJEVQFOUllipL+fQ7fonABAg1Y6T2U1J/t9cr8db0hNcrAABgTFGpFjnRnpVlEX0AQeMYo5MdWYWtqGJ6lS2b9yQAPhGNo0H4AnNFCEyA8DO0zpLcIetOuHa2AQDCwRij2opoxCV9aaPzXVkZKtWBQLEtS8mQzROJWdI0Bq0D8JFoHA3Cc45h2Lok9aaNLnYTmAChZdnS2Q+8XoX3ZiTc5wIAAJ9xjLtbOSqSl7Ii8gCCxRijkx0Zr5eRV7WVNhtEAfhKdI4G4TmGrbuOE5gA4dWbkjrPeb0Kb9kxqXaeO1sFAACfsS1pZoTikmR7hnY1QIAYY/Rxl6P+cOVEVFvJ+xAAf4nO0SA8ZVuW5sYjMtHwKpLtWQITIIycrHTmPa9X4b34XDcxAgCAD1mWFalKkfZeo+5+x+tlAJiE45dClhGRNKMqpmzYhqQACLToHA3Cc+UlluIVJAMu9TjqGSAwAULHjtE6S3KHrBve4wAA/lUaszStLDpxybGLWTm07wUCwQrhPBFJmjXNlh2dt10AAUBSBEVjjNGcGnYPS24LLYddEkC4ZAaki8e9XoX3ZiREj0AAgN9Nj1ALrQ8/TlOpDgSAY4xOd2TV2R++g+mZVcwUAeAv0TkShOeMEUmRy45eyMhmmwQQHk5WOt1GhYQkzVgo2RxeAAD8y3GMZkSohVaqz+h0imoRwO9sy9L7Z9NeLyPv4hWWSmKc/wDgL9E5EoTnbNvS9bX8yUnSx12O2nuyMgQmQDjYMenYm16vwntV06WyKq9XAQDAuCxLkUqKSNL7Z6kWAfzMGKOeAUcn2sPXOmtmhCrzAAQH70woqspSW9PKORiXpPfOhm94GhBJxpHaT0mpM16vxHvTE16vAACAq7IsS9dNi1YF+4lLWfUy1xDwLSPp4LlMKLvQzqxmyDoA/yEpgqIyxmguLbQkuS20ssQlQPBZtnTsDa9X4Q/TF7itxAAA8LmKUku1FdHZrGUkvX8uQwstwMc+/DicGydnVTNkHYD/kBRBURlJs2v4s5OkjCMdOk9gAgReus+dJwLpukVuKzEAAHzOGKO58Wh9Zh0K6QlXIOgcx+j4xaz60uE7N5BrV8iQdQB+w9lpFJVtWbq+NlrBx3gO0tsXCDbHkY6/TXWEJNXMkarqvF4FAAATYiTNi1hc0pt2T7yyKQvwF9u29P658A1Yl6Trqm2GrAPwJZIiKLrqMls1zBWRJHX0GZ1NEZgAgWVZblIE0vW3u0kiAAACwLYszY3HFLWo5OA5NmUBfmKMUUevo3Od4TyOnlcb43wHAF8iKYKiM8ZoQV20dmWN532qRYBgcrLSx4elnkter8Qf5tW7SSIAAAKiNGZpZnW0QuKznY46eh0ZTlICvvH+2XBWiUjSgrroJZ8BBEO0jgDhG4npJV4vwTeOt4ezdygQenZM+uhNr1fhD9NmSdUzSYoAAALFMUbXR2yuiBTuE7BA0GQd6cj5cM77KS+RpjNPBIBPkRRB0VmWpTk1tsqiF3+Myhi3jJ2SUiBAjJF6U9K5Q16vxB/m3i6ZcJb8AwDCy5IiOe/wyPmMsnxsA55zjNHh8xmlQ/p6vD4eIyECwLdIisATlmVFbrDheD48l6GkFAgUI330hvsv3NZZvIsBAALGsizNnmYrFrGoOO1IbWfStNACPGaM1Ho6vJVb82pjchzeZwD4U8QO/+AXjjG00BqiJ210/BID14HAMEZKvuv1KvyharpUM5vWWQCAQLJtS7OnRW+z1oHTaQ1kRWIE8IhjjN4/m1H3QHhfgwvqYrJtYgQA/kRSBJ6wLcsduMXn46D9pxi4DgSCcaSP3pIGerxeiT/QOgsAEGDuXJHohcVpR/rNyQGvlwFEVtaRWk+H9zVYV2mpojR6760AgoN3KHimNOaWq8N1scfRsQsZqkUAv3Oy0qHXvF6Ff9A6CwAQYJakeXXRqxSRpA/OZdSTNlSLAEVmjFHr6bT6wzlfXZI0v7aEcxsAfI0z0vAMLbRGeudEeHeKAKFgHOnwPqpEciprpdrraZ0FAAgsy7I0vdJWeQTDEsdI7yTTDEIGisgYo/6M9N6Z8M4SkaT5dTG2TQHwNZIi8IxtWbphejR3ZY2ls9/ow3NUiwC+ZIyU6ZeO7vN6Jf5B6ywAQAhYlqU5NdGMS45eyKi91yH+AIroNycHlAnxIXSJLc2eZpNwBeBrJEXgqepyW7Oq+TMc6ren0iImAXzqg19IGSq6Bl2/RLTOAgAEneMYXV8bzaSIkfR2coDZhkARGGPUPWD04cch7pslaU4NA9YB+B9no+EpxzG6eVYEa9XH0Zs2OnAmzW4twE+Mkfo6peNveb0S/yifJtXNp3UWACDwbNtSIqJzRSTpRHtW5zqzxB9AgVmWpbeTA3JC/lKbVxuTE/YfEkDgkRSBp2zb0s0zS8QmguFaT6eVyYqhh4BfWJZ08KfukHW45t7u9QoAAMibqjJbs6dFNzymWgQoLMcYXerJ6tjF8McTC+qoFAHgf9E96oNvlJVYmhfRcvWxpLPSb0/RogfwBceROs9LJ/d7vRJ/uX6J3KYbAAAEn2OiXcF+rsvRiXZmGwKFYluW3kqGe7i6JNWUW6qp4FQjAP/jnQqec4zRoggHIGM5eDaj3rShWgTwmm1L778sEgBDVNZJMxZKFocRAIBwsC1LN0W8gv3t5ACTwoACcIzRmVRWpzrCXyVy86wSkqsAAoGzGfCcbVlaUBdTKcUiw2SN9O6JtCzK2AHvOFnp0gnp3Ider8RfbrjXnbMCAECIlMYszY/wbJH2XqPfnkqzKQvII2OMHCO1HO33eilFcct1JbTiAxAIJEXgC7Yl3TCDapErHT6fUarPYacF4BU7Jr33ster8Be7RFp4j1tBAwBAiDjG6OaZ0Y5J9p9Kq6PPEH8AeZIbrt7VH/7X1JwaW9VlxAgAgoF3K/iCkXQLLbRGMJJ+fYyhh4AnHEc61SZdSnq9En+ZVy+VVni9CgAA8s62LCXqYiqLbrGIHCP98nA/bbSAPHCM0dnOrN4/m/F6KUWxiNZZAAKEpAh8wbYsza6JqbqMw+8rnU5l9eG5NAcXQDEZR8r0Sa27vV6J/9z0Gff5AQAghCwq2HWxx6GNFnCNcm2z9h6JRtusElu6cSatswAEB0kR+IZjjG6dHe0AZCxvHh9QX5oydqBoLFva/yMp3ev1Svylbr4Un8uAdQBAaBm5u52jjjZawLWJUtssyU0mx8iHAAgQzmrAN2zL0m2zS2XzQTpC2pFajtJGCyiKXNusM+97vRL/uWGZO3weAICQooLdRRstYOqi1jZLcgesRyP9AyAsSIrAV8pLLN0Y8XL1sZzqoI0WUHC0zRpbWZU0b4k7fB4AgBBzjNFNER+4LtFGC5iKqLXNkqRpZZbm1MTYxAkgUEiKwFccY3THXAKQsdBGCygw2maNLXG322gdAICQs+TuegZttIDJsixLbx2PTtssSbqZAesAAoikCHzFtizNrI5pZjV/mqOhjRZQQLTNGptlSTcuk2iiAQCIAMuyFK+wNaOKmIQ2WsDE5dpmHTwXnbZZknTrdSW8RwAIHI7y4DuOMbpjTqnXy/At2mgBBUDbrPHNXixV1FApAgCIDMcY3czAdUm00QImIoptsyRpdo2t6nJbFnECgIAhKQLfsS1LN86IqYIYZEy00QLyjLZZ47vps24lDQAAEWFblm6eye7nnN+eTOtMyiH+AMZgWZZ+ebg/Um2zJOkWWmcBCCiSIvAnS7r1OqpFxkIbLSCPaJs1vrr50swbJJtDBgBAtFSUWrphRszrZfiCkfTzQ33q7jdyHE6AAkMZY/SbkwM6finr9VKKqsSWbpxZwnkJAIHEGQ74kiXp9jkldGoZx6mOrD6gjRZwbWibdXW3fk5yohXgAQAguS20ls5jo1bOQFZ69YM+OUa00gIuc4zR8UtZ/eZk2uulFN3C6SUqsTlpAyCYSIrAlyzLUmWZrZtm0kNrPG8cH1B7D2XswJQY4369+SJts8YSnyvNvlWy2SULAIge27I0oyqmuXHC5pyOPqOfH4rWzARgLI4xSvU6kZsjkrPkelpnAQguju7gW8YYfXpeKX18x5F1pFc/6NdARhyMAJNlWW6FyKWk1yvxr1seoEoEABBpjjFaej3VIkOd7Mjq7WT0dsUDQznGKJ2VXvmgX5kIjt6bVxvTjKoYrbMABBZJEfiWZVmqqbDp43sVPWmjVz/skyhjBybOGOnY61LyHa9X4l/TZklzb6dKBAAQabZlaV5tiaZXEToP1XYmrSPnM2zMQiTl4u6ffdin7oFovgY+Na+U1z+AQOPIDr7mGKNPzy/zehm+d77L0b5jA7LYpQFcneNIFz+SDvzE65X426L73ZkrAABEnGOMls6lWuRK+4726xKtfBFBlmXp18cGdLYzmsfKs6fZml1DlQiAYCMpAl+zLUu1lbYS09mpfDWHz2d04EyaahFgPI4j9XdKb32fE/7jqayT5i+lSgQAALkxyY0zY6ou4wTgUFlDK19EjzFG759N68OPM14vxTN3ziuV4/CaBxBsJEXge44xums+O7Mm4q3jAzqTYrcWMCpjJJOVXv+vDFa/msW/6z5fAABAkmQkLaFaZITetNGrH/S5h1kcOyDkHGN0rtPRG8cHvF6KZ6ZX2ZpfVyLbJkkMINhIisD3bMvS9KqY5teyY/lqjKSfH+pTd79h5wYwmrd3SV0fe70Kf6uZLc2/kyoRAACGsC1Li2eXqLzE65X4z/luR3uP9EsiMYLwcoxRV7/Rzw71RXrv0J3MEgEQEiRFEAjubBF2Zk3EQFZ69YM+ZdmtBQx38KfSuQ+8XoX/3b6C1mIAAIzCsqTbZhOTjObYxSwzDhFajjHqGTDa816f+qPbNUs1FZZumM4sEQDhQFIEgWBblmZNi+n6OH+yE9HRZ/SLQ/1eLwPwB+NIp9qkw3u9Xon/zbhBmn0LVSIAAIzCtizdMbdUMUKSUR36OKNfHyMGQbg4xqgv7SZEetPR3nS49PpSRfsZABAmHM4hMBxjdO/CMq+XERgnO7J6O5n2ehmAt5ys1HlO+s0/eL2SYLhjpTuMHgAAjKosJt0yix5aYzl4LqM3j5MYQTg4jlF/xk2IdA9EOx1QXWZp0awSqkQAhAZJEQSGbVmaURXTTTPZwTxRbWfSaj0V3SFwiDgnK/Vckn79f0tOhOvcJ2ru7VLdPMnm0AAAgPHUX18qTguO7cCZjN45QQyCYHOMUdqRfvxenzr7o50QkaQlc2kdCCBcOPOBQDHG6N5EmWJEIRP29om03jtDxQgixslKfSnpV38nDfR4vRr/syzp9pXMEgEA4Cosy9K0cls3zGCj1nj2n0rrnSSJEQSTY4wGMkbNB3rV0UdCpKJEWjybKhEA4UJSBIFiWZYqS91evpi4N44P6OC5NIPXEQ1OVurvkvb9rfsvrm7hvVJVnWRxWAAAwNU4xuiuBWVUi1zF/tNpvUErLQRMbobI7gN9JEQuu31uqciHAAgbzn4gcCzL0qfmlaqcVr6T8utjAzp8PkNiBOHmZN3KkH1/K/V1er2aYCirkm7/oterAAAgMGzLUk25pVuvIyC5mvfOfDJ8nTgEfucYo94BNyFCyyxXaUy6Y04pVSIAQoekCALJtqVPz2fo+mTtOzqgYxeyBCQIJycrDfRK+/6z1Nvh9WqC4/YVkl0qtn8BADA5dy8oUwkR9VUdPJdRyxESI/A3xxh197sJkagPVR/qzutLFeN9DkAI8daGQLItS7fNLlG8gpN4k2Ek/fJIPxUjCB8nK/V3Sy07pJ6LXq8mOOrmS4m7GK4OAMAkWZalshJp6fW09Z2IQ+cz+vmhfjnGPfkM+IkxRhe7He1+r089af4+c6aVWVoylyoRAOHEWRAElpF0b4JqkckyklqODuiDcxmvlwLkh5N1W2W17JB6271eTYBY0p0PSg7D1QEAmArLslR/fakqSzlhOBHHL2W1+0Cf+tKGxAh85cj5jJrfc/828Yl7F5aJ4UkAwoqkCALLtiwlppdobpw/46n49UcDOnAm7fUygGvjZN1ESMsOqS/l9WqCZeE9UnwuVSIAAFwDy5LuXkC1yERd7HH0w9ZeXehyqFyHp4wxMsbojeP92nt0QA5/jsPMrrF1w4wSqkQAhBZnQhBojjFafmO5bD6np+TN4wPaf2pAEv19EUCOI3VflFpekPq7vF5NsJRVSXeskHjdAwBwTWzL0qJZJZpeSWg9UX0Zac/7fTr0MZXr8IZjjDKO9MoH/XrvDH+Ho/nMwjIqugCEGkduCDTbsjSt3C1bx9S8cyKtXx3rlxH9fREgxkjnj7gVIgM9Xq8meBiuDgBA3hhJn7mRtr6T4Rhp37EBvf5Rv4yhnRaKxzFGXf1GP2zr1amOrNfL8aVFs0o0ozpGlQiAUCMpgsCzLEufmleqaeV8YE/VB+cy+sn7fcpkSYzA53J/n0f2SW/slDL93q4niGbdxHB1AADyyLYszamJ6cYZMa+XEjjvn83o5YPEISgOY4xOd2T1o7Zedfbx9zaaElu6N1FKJwkAoccZEYSCZUn/f/buPL6N67wX/m8GC0FSBKF9IyhRkrWQkm3JlhNRWbwoIaUkTcI0hnLbtFIqWn3fJlKbSL03acSmstr0lox75eTetzLVSEnbG8FOaadJJNKWtySCHMu7CC22NgvaV3C4E8Cc9w9wIIIASADEjt/38+FH4mAwczAEwfPMc855PjqLo7PG4mqnf31fpY8jtShDqSogVOCd54ATL8I/LpNiojMAd/8Bi6sTERElmBACy8uN0DPCjtllRQ3cpGYcQsmg3eA/dsWDl97vh4cTRCK6Z6YRRr0EibNEiCjHsctGOUGWJMyw6FExkaOzxqJrQGC/sxcX3D6ODKHMovoAT6+/fsjFo+luTfZa8DBgGsdZIkRERAkmSRJMBglLZnBZ33h09vvjkEsdjEMosVQhoArgd6f78abLw2FVI7AUSqicxuLqRJQfeFeEcoYQAg/MKkCBPt0tyW5eFXjlg368d8kDgAXYKQMIFei8Bvz2KaDjUrpbk70mlAOzlwMS//QTERElgyT5ax2WcFnfuHhU4OX3+/GGawA+VUBVGYfQ2AghoPSq2H+sD2dusqD6aD46u4BJIyLKG7wzQjlDkiQYdMD95VxGKxHevejBKx/0QRVc35fS7KLTP0OkvyvdLcleOgNw7xfAJceIiIiS7wEu6xs3AeD4FS9+2d6Lmz0qB2hRXPyzQwTeu+TBr5x9uN3DpWNHM2eSHlNKWFydiPIHkyKUU2RJwtxJBswo5TJaiXD+tg/7j/Whz8P1fSnFhOovqn78BeDd5wCVI7vGZOEjgKmEs0SIiIiSTJYkzLToUT6e8chYKH0Crcf68CZnjVCMArNDnH1496IHfOuMzqgDlpcbmYQkorwiCX7qUY5RhUC/R+AXR3sxwAJqCWHSAw/eZcLkcTILrlHyqT7/11v/CVw/le7WZL+JFcBH/zjdrSAiIsobQggM+IBfHO1Fn4fh9liZTRJWzinApGLGIhSZNojv6CUPjl5iMiQWH5llxF1TWEuEiPILkyKUk1Qh4Lrtw6un+tPdlJwhS8CSGQbcPcMAAbDDRMlzywW8+wug53a6W5L9jEXAJ/4cMBZylggREVEKqULgUocPL73PeCQRJACLpumxtMwICYAsMxahO4QQ6OhV8bszA7jFpbJiMmWcjJpFJiYciSjvMClCOe13p/tZUC3BJhTJ+NjcApSaJHacKHFUn3+5rBMvAudeT3drcscD/80/U0RmQoSIiCgdDp/txwfXGY8kCmeN0FCcHTI2Bh3w+SWFMBkkDnokorzDpAjlLCEEfCrwX0d70TXAt3kiyRJw9wwDlnDWCCUKZ4ckXsVHgMpPp7sVREREeUsIAZ8YjEf6GY8kStCsEYmxSD4SQkCSJLh7fJwdMgYfn1uAWRNYXJ2I8hOTIpTTVCFws1tF67E+8I2eeJw1QmPC2SHJY54GrPwaILPIKxERUToxHkmeYqOEu2caMG+SHkJwSa18oN2+6vMIvH3Rg9PXvfy9itOciXp8bG5BuptBRJQ2TIpQzhNC4J0LHhy97El3U3ISZ41Q3Dg7JDl0RuATGwGTmctmERERZQAhBN6+4EE745GkKDVJWGo1ony8HqoQjEdylCoEvD7/Ulknrnrg452suI0rkPAHiwuhk8HBjUSUt5gUobygCoEDx/pws5vTapOFs0YoKpwdknz3fB6YuZiF1YmIiDKIKgT2O/u4zE8STSqWcV+5EVNLdEyO5BBVCAgBHLviTyx6fOluUXaTANRWmjCxWObvCBHlNSZFKC+oQqC7X+CX7b3wMg5JGs4aoYiEACSJs0OSzXovcPfn0t0KIiIiGkYVAp19Ar9q7+UI9ySbUarDfVYDxhfpArUnKPuoQkAC8P51L9676EGvh784iXDPTAPunmHg7wUR5T0mRShvqELgw1s+/PZ0f7qbkvPGF8q4r9yAGaWcwk7wJ0QGuoGTLwOud9LdmtxlmQms+FP/DBH+zhEREWUcIQSOX/XijfMD6W5KXpg9QYdlViOKjf5+EW8CZwctfjx304u3Lwygs5+3rBJl8jgZtYtM/F0gIgKTIpSHjnzYj+NXveluRl6YWiLj/nIjJhZzCnteEirgHQBO/Q44dwRQ+XuXNAXFwMcfAwxFrCNCRESU4Z4/0YsrCqevp4IsAXdN1mPJDAOKjDJjkgym/Wwuub1464KHS80lmEEH/MHiQhQaJf4OEBGBSRHKQ0IIPH+iD1c72clKlfLx/lFaZpPMKez5QFX9CZGzvwdOHwK8nJ2VVJLsnyFSOh2QdeluDREREY1AFQJ9HoFfHO1lbYQUkgCUWXRYONWA6aUcsJUptCWyvCrw/jUv3r/m4cyQJPnYnALMnqjj+56IaBCTIpR3VCHg8QL/1d7LdUlTSAIwd7IeS2caYDKwGHtOUn3+ZZvOvw188BugvyvdLcoPi1cD5ctYWJ2IiChLqELg3E0ffneGA0fSocQkYcEUA+6arIdeBmshpoGqCsiyhFvdPhy/6sW5W174OGYxaSom6vDxuaZ0N4OIKKMwKUJ5SRUCt7pVtB7vg8rfgJTSScDCqf5i7HodA5CcoPr8MxQuOYGTrwA9t9LdovzBwupERERZy3G2H6euc3nRdNHJQMUEPRZO02NCkS5wo56SQ7v1pArg7E0vTl7z4mY3MyHJVmyU8AdLCqGXWVeHiGgoJkUobwkh8P41L37/IQsdpoNBByyebkDlNAMkicmRrKQlQ26cBY4fBJQr6W5RfmFhdSIioqwlhIAA8AKX9c0IE4tlLJiiR8VEPbS8CG8gJ4aWbOrqV3Hiqgenb3jRz1xgSkgAaheZMHGczHibiGgYJkUo7x0604/TN9grS5dCg4T5U/RYMMW/rBbX980CYjBwv3LCX0D91vn0ticfFY0HPvZngL6Ay2YRERFlKVUIeH3Ar5y96GIdhYxQoAcqJuoxa7weU0pkSJLEGSRx0GK6fq+A67YX5275cKmDRXRS7YFZRiyYomeCj4goDCZFKK8JIaAKoPV4H6fuppks+QuyL5hqwNQSFj/MOKoKyLK/TsiHb/rrhvR3prtV+clYBKz8M8BUwsLqREREWU4VAp19AvudvfAwHMkoRh0w06JDmUWPMosOBh0TJJFot5UkSUJHrwrXbS9cbh9udKngDaf0WDhVjwdmFaS7GUREGYtJEcp7WuH1Xzt70TXAX4dMYCmUMH+KAfMm6aEbHATP0S1poi2RdfOcf1bI1ffvzBSh1JP1wIo/AczT/UkqIiIiynqqELjc4cNL7/fzBnKGkiVgaomMMose5RN0KDbKUIWAhPyNU7QEkRAC1zpVnL/txQW3D52c9ZR2My06PHxXQd6+N4mIosGkCBH8gUhXv8CBY71c3zSD6GVgziQ9Fk41wFIoc2RWqggVgAT4PIDrbeD8W0DXjXS3iiAB930ZmHoXl8wiIiLKMUIIHLvixZsu1jvMBpZCCdbBBMnEYv/MXXXw1kquznb3qQK6wVjM4xO46PbB5fbiotuHAa6MlTHGF8lYXWmCTsrfhB0RUTSYFCEapAqBG10qnj/RB5W/FRlnyjgZC6YaMGuCDhIAgdwNONJGCH/B7s5rwNnXgUvt/sQIZYbKTwOzH2BRdSIiohzGeofZx6ADJhTJmFgsY2KxDpPHyRhX4B/Ako2JEm2JaS0B4lMFbvWouNGl4ma3ips9Pii9grOaMlChQcJnq0woMEhZ9Z4jIkoHJkWIhhBC4MPbPvzmVH+6m0IRmPRAmUUP63gdZpTqoJO5tm/CCAF03wJe/T/pbgkNV/ERf1KEiIiIcpYQ/hvNzx/vw7UuLleazUZKlGhJBwlIawwTaId0J2nDBEj20stA7SITLEUyEyJERFFgUoRoGP/UdQ/edHGEfKbTScC0Uh2sFh3Kx+tgMnBt34R44QfAQE+6W0Ea673A3Z9LdyuIiIgoBVQh4PEBv2rvRTfrHeYULVFiKZRRaJRQZJBQZJRQbJRhMkgo0AfHL0OTJxh8SNtjeKyjJdTufB+c7NCoQqDPI9AzINA9INDrEegd/D8TINlLAvDgXQWYadExIUJEFCUmRYgi+P25fpy8xqnr2WRisexPkEzQw1IoB4IDdgxj9Paz/qWzKP1mLgHu+bz//3wfExER5QVVCCh9AvudvfBywkjekCX/8keFBimQNNG+l2UJsjSY6MDgvzIAAaiDX0L7F/7EWo+W9PAI9Ayo6PUI1s/MUfdZjaicpufAQCKiGDApQhSBEAKvfNAPl5tV47JRsVGCdbwO1vF6TB4nQz84NV1VBSQWnYtM9QEX24H3/ivdLaHpVcDSL/r/z/crERFRXlGFwCW3Dy9/0M+R+0QU0V2T9VhRUZDuZhARZR0mRYgi0KYrv/R+Hy4rHKKVzSQAZpOEicU6TCiWMalYxoTiO4kSnyoGR15l143noUuFCSES1/7+buDgE4k5FsVn2kJg2ZcASEyIEBER5SkhBJyXPXjrApf1JaJQ0806rFrgT4hkWyxLRJRuTIoQjUBLjBw82YernUyM5BItUTJhsPjh8ESJKkTEtXhTaehawtoMFyEEOvsFrnepuNXtg1EP3DMzwaODfrML6LyW2GNSdKbcBdz/KJgQISIiIgA4cr4fx69w3SMiuqO0UMKaykLoZSZEiIjiwaQI0SjUwZvSL5zow/UuJkZymZYoGV+kFT+UUWiQUGz0F0E0GSQYdKHFCkUUBRC1j9poCyD2ewR6PALd/f5/tSKISp+KWz1q0PrSJj3w6LLihFwDf8NU4PiLwNnXEndMis7kucD9NkCSmRAhIiKigCMf9uP4VSZGiMhfe2ZNlclfb4YxAxFRXJgUIYqCKgRUFXj+RB9udDMxks/0MkKLHxolFOj9xQ9lSQrM6pAHvwSCix/6/y/gVRNXAPFzi02wFMqJGSUkVODGOeD1/xj7sSh6EyuAB74yOCVITndriIiIKMO8/mE/TjAxQpTXCg0SaheZUFzAhAgR0Vjo090AomwgSxIgC3xqoQltx/twq4eJkXzlVYHOfv/yVZnkgtuHUpOcmMkFkgxMLAdkPaAy8E6JCeXA8rVMiBAREVFED8wqgBDAyWvsnxHloyKjPyFSZGRChIhorHjnhShKsiRBJwOfXmjC+EL+6lBmudThgywnsGMs64EJ1sQdjyIbXwY88N8AWWZChIiIiEb0kdkFWDCFYxuJ8k2xUcJqJkSIiBKGd1+IYiBLEvQ64NOLTLAUsiNCmeN6lwqfmsDZK6rPX9+CkmvqAuAjXwVkHRMiREREFJWPzC7AXZOZGCHKF+OMEmorTShkQoSIKGF4B4YoRrIkwaADahcVYmIxf4UoM6gCuKL4oCaqTJSsAybPS8yxKLzZDwD3fZkJESIiIorZigomRojywbiCwYQIi6oTESUU78IQxUGbMVKz0IRpZv4aUWa42OFDQrvJJZOBgnGJPCIBACSg8tNAVc1gDREGN0RERBQbIQRWVBRg3iQmRohyVUmBf8ksExMiREQJx7u5RHGSJQmyDKyab0L5eF26m0OESx0+SInuLE+ak9jj5TtZ758dMvuBdLeEiIiIspgkSYOJESPmMjFClHPMJv8MkQImRIiIkoJJEaIxkCUJkgR8cl4B5nH6OqWZ0ifQM6Am7oCqD5jMpEjCGIuAFX8KTL2Ls0OIiIhozLTBMNUVRsxhYoQoZ5SaJNQuKkSBjgkRIqJkYVKEaIzuBCMFqJpuSHNrKN9ddPugJqrgOuuKJE7xROBjGwDzVNYPISIiooTRYpGVFUbMmcjECFG2sxT6EyJGPSDLTIgQESUL78wQJYAWjNxnNeI+qzHNraF8dknxJbbzbCwEzNMSd7x8NN4KrPyavz6LzKX2iIiIKLECiZE5RiycysQIUbayFEqoWVQIgx6cIUJElGRMihAlWNV0A1ZWGMFBHZQOVxQfhEjQTBEAECrriozF9Crgo18FdEYmRIiIiChpJEmCJEl4YFYB7i83gqEIUXaZWCyjdlEhDDomRIiIUoHDSIiSYM4kPcaZZLzyQR/6veluDeWTfi9wq0fFhCI5QUXXJWDKXOCMIwHHyjNzq4GFjwBCsIYIERERpcyiqXqMM0r47el++BI4VibVjrz4LNpffylo26NffxzFJZYx7TvcuRPv4Fc/acKjX38cU2ZWjKXJRHEpH6/Dx+cWQJKYECEiShVJJHRIMRFpVCHQOyDw4vt9cPfy14xS596ZBiyeYUhch1r1Ac83Aj5PYo6X6yQJqFoNzLov3S0hIiKiPCWEwM1uFS++n52DtOw/2obFDzyMqgceCmy7dvEsfvTtr+K//+9fBSU7Ytk3nCMvPosffeero7apseUokyaUcFXTDbjPaoQQIkGD2oiIKBqcKUKUJLIkodAIrKksxKun+3HR7Ut3kyhPXOrw4e6ZCaxtI+uACeXA9dOJO2au0hcAS78ETOaSY0RERJQ+kiRhQrGMz1QV4oUTfejsz55BWudOvAMAQUkOAJgyswJf+86PsOcfvo6vf//fY943kjPH38KDX1iPKWXh+29dHbcCxyRKFFkCPjrbiHmTDQDAhAgRUYoxKUKURLIkQZIFHr6rAG+5PHBe4Uh7Sr7r3Sq8PgG9LoEzRSbPZVJkNOPL/AkR0zgul0VERERpJ0sSiozAZ6oK8fIHfbjaqaa7SVFxHnkZcxYtC/vY7IX34tzJd+PadyTrv/3DiI/Zf7QNtq8/HtVxiKJh1AEP3mXC1BKW+SUiShd+AhMlmVb08L5yI1bOYQF2Sj4hgMuKD2qiVkeUdcCUeYk5Vk6SgHkfB1b8KVAwDpD4p5WIiIgygyxJ0OuATy00Yf6U7BkT+fJzPw67/drFs5gyc3bc+4YTKakCAC8/+2M89MWvjXoMomiVmCR8pqoQU0oSVQOSiIjiwTs3RCk0Z6IetYtMMBnY+aHkutThQ0LfZcUTAZM5kUfMDaYSYMWfAPM/6U+GyPyzSkRERJlFliTIkoSPzi7AR2YZM35C6/KHvwDn6y/jR9/+Y3R3uoMe+/VPn8BnvvrNuPaNeL5Hvhh2+7WLZwFw2SxKnJmlOny2qhDFBRILqhMRpRnv3hClkLa27x8sLsQ0M3/9KHkudfgSO/JICGASA8IgUxcAn/hzwDKTy2URERFRVpg/RY9PLzChIIMnjUyZWYFHv/44jrz0HLZ8cTGcr78MwD9rY3hB9Vj2jdWvf/oEZ4lQwiyZbsDD8wugl8GECBFRBpCESNT6KkQULVUISADeu+TBexc94C8hJcOX7ilEcUGCkm+qD7hyAni7JTHHy2ayHqj8FDDrfn+yiEENERERZRFVCPQOCLz4fh/cvZkbiRx58Vn86DtfBQBMnlmBv/7hf0WctRHLvtF4+dkfo2LRMsxeeG/cxyACAL0MfGxOAconZHAmkogoD3GoOlEayIN1Ru6eYcCnF5lQyOW0KAkudPigqgmsKzJ5LpDYRbmyT8kU4OOPAeWDa08zIUJERERZRpYkFBr9dQ3umpy5N2qLSixY89W/QtUDD+H6xbP4p2/8Ac6deGfM+0bjyEvPMiFCY1ZS4P89KxuvS3dTiIhoGCZFiNJIkiRMHifjD5YUYmYpO0qUWJc7fJDlBN60N5iA0mmJO162mXU/8LENQNF4FlMnIiKirOavMwKsqCjAg3cVZNxyWvYfbUNPpxu2rz+Ov/7hL7HufzyJ6xfP4m//9GOBJbLi2TcaLz/7Y8xacG+CXgnlq/LxOnx2cSFKTKwfQkSUiXhXhyjNZEmCUQc8ssCE+6wGDjynhLms+JDQFRJVdXC2SJ4xFAL324DFq1lMnYiIiHKGVn+uzKLD55cUYbo5MwZpvfzsjwEEF0B/6ItfQ2PLUUyeWYEffeergaLqsewby/kXP/Dw2F4E5S2DDlg5x4gH7zKxfggRUQbjnR2iDKAFJJXTDFi9yIRxRnacaOw8PuBmt5q4xIgk5V9SZOIs4JN/Dkye5/+eQQ0RERHlGFmSYNQDn1powv3lRiRyonE8fv1v/wzb1x8P2T5lZgX+7ie/BQAcG5wBEsu+0bh28Sw+PPkOJs+cHUfLKd9NM8v4/JJCVEz0T72SGDsQEWUsJkWIMogkSZhQ7F9OK5PX96XsccHtQ8LmikgSYCkDdMZEHTFz6YzAolXAR74KGIo4O4SIiIhymjaafdFUPT67uBCWwvTczO3udKNoXGnEx4tLLPjsn34L1y6di2nfaGnLbY2lSDvlH50ELC834tMLC2EycLksIqJswLs8RBlGliToZP/6vqsWFKCIRdhpDC4pvsR2ymUZmDg7ccfLRDOqgIf+Aqj4iD8RxIQIERER5QlJkmA2SfhsVSEWTU39IK3iEgt6ujpG3W/KjNkx7RutcyfejnpfIgCYWCzjc0sKsXDw94UJESKi7MA7PUQZSJtmO82sw+fvLsTcSZw1QvG52aXC40tkXREfMHlO4o6XScZNBlb8KbC0DjAWs5g6ERER5SVZkiDLEpbPKsCnFphQmOJBWlNmzh6xQLrz9ZdQ+cBDMe8bjeuXzqGoxBL1/pS/JAm4Z6YBaypNGFcgcaksIqIswzs+RBlMliToZWDlHH9AUsxaIxQjAeBShw9qouqKyDpgyrzEHCtT6AuAyk8Dn3gMsMz0b2NQQ0RERISpgzUSrONTV4T9L/7h32D/0baQZEd3pxt7vv8NfOar30TxYOIiln0B4Eff/mNsqVsS8dzXLp5L1MugHGY2SVhTacLdMwyQJC6XRUSUjTj8nCjDaSNOppplfP7uQrzlGsCJq940t4qyyaUOH8oTGcgWjQcKLUCvO3HHTJeZdwOVnwIMJv/MEMYzRERERAGyJMGgE3joLhM+uObBkfMD8KrJPWdxiQXbf/o72H+0Da+/2BL02KNffzwoyRHLvpqR6pDMXnBPVEtyUf5aOFWP+6xGSBILqRMRZTNJiEQNHyaiZBNCQJIk3Ojy4bVzA7jVk+SIhHLCOKOEunuLEndAIYCjvwZcWbzmsnkqsHgNML7M/3oY0BARERGNSBUCfR6BI+cH8OEtX7qbQ5RSxUYJK+cUYJo5dbOmiIgoeZgUIcpCqhCQAHxw3Yu3LwygnxNHaBRfvKcQJQUJWjFRVYGrJ4G3fp6Y46WS3gQseBCYdT8gVP9yYEREREQUFW2Q1tVOH35/rh/uXt5OoNwmS8CCqXrcO9MIncxC6kREuYJJEaIspgoBnwq8fWEAJ696wV9miuSBWUbMn6yHLCeoE+/tB55v9M+yyBbWe4FFq/w1RFhEnYiIiChu2iCt96958c5FDtKi3GS16HD/LCPGDdb25HJZRES5g0kRoiyn/Qp39An8/lw/rnZySS0KVWbR4eH5psQe9NCPAffFxB4zGUqn+5fKsszgUllERERECaQKAa/PP0jr/WscpEW5YXyRjOXlRkwz66AKwdkhREQ5iEkRohyhddbO3fLizfMD6B7grzbdYZAB231FievQqypw6rfAB79JzPGSoXQGMP8TwJS7ANXHpbKIiIiIkoCDtChXmAwSls40YN5kPQS4VBYRUS5jUoQox6hCQAjg2BUPnJc9GGANRBpUu8iEyePkxEz7FsI/S8SxZ+zHSrTxZcBdnwQmz2EyhIiIiChFOEiLspUsAZXTDLh7hgEy64YQEeUFJkWIcpRWb6T9sgfHr3jg5YCtvLdkugH3lBkS18kXKvB8k7++SCaYMMs/M2TibCZDiIiIiNJEG6R19JJ/kJaPdxwog82eoMN95UYUGSTWDCEiyiNMihDlOCEEBnzA0Uv+YuwMSvLXxGIZn6kqTOxB33wGuHIisceM1aQKYP4ngfFW/7JeMouoExEREaWbEAI9HoE3PhzAh7c5fZ0yy8RiGQ/MMmLyOB2EEEyIEBHlGSZFiPKA9mve7xV496IHH1z3QuVvft6RANiWFcGoT1RdER/gegdo35+Y48Vq8jx/MsQyg8kQIiIiogyk3Wzu6FXx3qUBnLvpYzF2Sqtio4R7ywyYO8nAIupERHmMSRGiPKL9uvd4BN654MGZm17wEyC/fGJuAcon6BLX+e9VgJd2JuZY0ZB1wPRKYM5HAfM0JkOIiIiIsoCWHOnuV9F+2YNT1zmDnVLLUiiharoBFRP1AFg3hIgo3zEpQpSHtKCkZ0DFsSv+mSMezmjPC/Mm6bGiwpjY6eEv/wjouZ2444VTMA6YdR8w637AWOSvZyIxGUJERESUTe7MYAeOXfHg5DUP4xBKqmlmGYunGzCjVM+ZIUREFMCkCFEe0379fSpw8poXJ6560D3Aj4RcVmSU8If3FiXugEIAzgPAh28m7phDjS8DZj8ATF/k/56JECIiIqKsp8UhXhU4ftWDE1c86POmuVGUMyQAsybosHiGAROKdEyGEBFRCCZFiAgAoAoBCcC5mz44r3hwq0dNd5MoSb5wdyHMpgQlF4QKXP0AePPpxBwPAHRGfxKk4oHBJbJ8/mWziIiIiCjnqEJACOCD6144L3OQFsVPLwPzJutRNc2A4gKZyRAiIoqISREiCqJ1HK8oPjgve3Cxg/PZc8395UYsnKKHLCcoQPAOAM83+hMkYzFxNlB2NzC9ajAJIjgzhIiIiChPqIO3Js7e9KL9kgcdfbxVQdEx6YGFUw1YONUAw+BYqoQuF0xERDmHSREiCktLjnQPqPjgmhenbnjRw1FbOWFmqQ6PLDAl9qCOvcBtV+zPKxrvT4RYlwKmEs4KISIiIspzWhziuu3FyWteXO7wgVEIhVNiklA1zYC5k/SQJBZPJyKi6DEpQkQjEkJAwL8u6+UOH96/7sUFtw8qPzmyll4G1t5XlLigQfUBpx3A+69Et7+xGJi2AJh5NzDBCqgqIHNGCBERERHdoaoCsiyhZ0DFB9e9OHXdy6W1CLIElFl0mDdZj5mlOggwGUJERLFjUoSIoqaN2ur3Cpy67sEH171QOK09K316oQlTS+TETCsXAlCuAL/bHXkfk9mfCJleCYy3ak/k8lhERERENCqt/uGVThUfXPPg/G0O0so3E4tlzJ2kx5yJehj1EuuFEBHRmDApQkRx0Tqh17t8OH3Di/O3fejz8OMkW1RNN2BpmSFxgYQQwAtNgKfvzrai8cC0hcCMKqB0un8fJkKIiIiIKE5aDDLgFTh704uzN7241jXGunaUsQoNEuZM1GPeZD1KC+XA7CEiIqKxYlKEiMZEG7UFANe6VJy76U+Q9DJBktEmFMn47OLCxB70neeAvk5gyjxgyl3AuEmDxdclgKO4iIiIiCiBtBvk3QMqztzwJ0jcvYxBsl2BHigfr0fFRD2mltwZTMXC6URElEhMihBRwgz9OLnRreLsYIKEBdozk21ZEQr0CawrohVIZ7F0IiIiIkohbQaJu9efIDl3y4uufsYg2cKo8ydCZk/UYbrZH0ewVggRESUTkyJElBTaR4skSbjR5cOHt3243OHDrR5Ob88UH5tTgNkTdJyCTkREREQ5QQgRuJne1a/iotuHSx0+XOn0weNLd+toqJICCdPMOljH6zCjVAcJTIQQEVHqMClCREk3NDjp9wpcdPtwWfEHKFxmK33mT9bjI7ONnIpORERERDlJW2JLFQI3ulRc7PAP1LrZrYJRSGoVGiRMM8uYbvYnQYqMclCcSERElEpMihBRyqmqgCT5Z5F09PqDk0sdPlzr9MHLiSRJo5eBKSU6TDPLmFmqw/giHYQQTIoQERERUc4begN+wCsCg7QudfjQzeV+E86oA6aZdZg2mAQxm/z1QVgsnYiIMgGTIkSUdkNHcN3uUXGtU8WNbh9udKno5FrAcSsxSZhcrMOkcTKmlMiwFMqQJSkoKUVERERElI9UISDB3yfu7FNxwe3DJcU/UItLbcUuMACrRMaMUh3GF8mQBmMPJkGIiCjTMClCRBnHpwroBjvOA16B610+XO9ScaNbxY0uHwYYpIQw6oBJ43SYVCxj8jgZk8fpYBwsoj70ehIRERERUaihN++7B1Tc6lZxq0fF7cEvDta6Qy8DpYUySgtljC+UMHmcfyCWLElBySYiIqJMxaQIEWW84WvNdvX7gxR3750vpU9AzYNPM4MOKDX5Z32UFkqwFMqwFMkoNg5OR2cQQkREREQ0ZkIICIFAosSrCrh7VNwckii53aPm9PK/suRPfli0uKNQxoQiGUVGKRBv+FQBmbPQiYgoyzApQkRZaXiQIoRA94BAR6+Kjj4Bpdc/mqvHo6JnQGTVFHijDigySig2yigukPxJkCJ/EFJouPN6VQEGIEREREREKTR8KdrufhU3u1Xc7lXh7lHR4xHo9Qj0eUTWJExkyb/07vjA7A8Z44tkjCu4k/zgErxERJRLmBQhopwSKVngU/3BSXe/P3nSM+APWHoGBPq9/qSJxyf8XyrgS2AAo5MBg06CQQcYdRIMMmDUSyg0SCg2Sig0yhhnlFBc4N82dKkrJj+IiIiIiDKbKgQwZMCWxusT6PMK9A4IdA8mSnoH/HHJ0K8+r3/AV6LoZcBkkFCgl2DSSzAZ/P8WGOD/Xi+h0Oj/16iXYNDdabeqCkC6M0ufiIgoFzEpQkR5R9VmmYyQaFCFgE/1BzIDgwmTwKflsKcMP4KWANHrJOjlyAGFlvCQGHQQEREREeW0QN8fCDvjYsAr4FX9+wS+hnzvG4xFJAzGMYPfaMeTJQkmg38QVrh6gloMFOn8RERE+YRJESIiIiIiIiIiIiIiygtyuhtARERERERERERERESUCkyKEBERERERERERERFRXmBShIiIiIiIiIiIiIiI8gKTIkRERERERERERERElBeYFCEiIiIiIiIiIiIiorzApAgREREREREREREREeUFJkWIiIiIiIiIiIiIiCgvMClCRERERERERERERER5gUkRIiIiIiIiIiIiIiLKC0yKEBERERERERERERFRXmBShIiIiIiIiIiIiIiI8gKTIkRERERERERERERElBeYFCEiIiIiIiIiIiIiorzApAgREREREREREREREeUFJkWIiIiIiIiIiIiIiCgvMClCRERERERERERERER5gUkRIiIiIiIiIiIiIiLKC0yKEBERERERERERERFRXmBShIiIiIiIiIiIiIiI8gKTIkRERERERERERERElBeYFCEiIiIiIiIiIiIiorzApAgREREREREREREREeUFJkWIiIiIiIiIiIiIiCgvMClCRERERERERERERER5gUkRIiIiIiIiIiIiIiLKC0yKEBERERERERERERFRXmBShIiIiIiIiIiIiIiI8gKTIkRERERERERERERElBeYFCEiIiIiIiIiIiIiorzApAgREREREREREREREeUFJkWIiIiIiIiIiIiIiCgvMClCRERERERERERERER5gUkRIiIiIiIiIiIiIiLKC0yKEBERERERERERERFRXmBShIiIiIiIiIiIiIiI8gKTIkRERERERERERERElBf06W4AUb5xOp3Yv38/Dh8+DJfLhdLSUgBAZWUl1q5di+rq6sC+iqJg165d2Lp1a0Lb0NzcjKeeeipku9aWjo6OqLYDwOrVq7F9+/aEti/TNDQ0oL29HYqiwOVy4ciRIzCbzeluVlKM9bVu2rQJFy5cgKIo6OjowJEjR5LYWkoHIQQ8Hg9UVU13U4goi8myDIPBAEmS0t0UIiIiShPGFkSUCPHEFkyKEKWIy+VCQ0MDHA4HbDYbHn/8cVRVVQU9vm/fPuzbtw87duyA2WxGU1NT0tqiKApqamqwceNGWK3WoBvfLpcLq1atAgDs3LkTtbW1Qc/XEju7d+9Ge3t7UtqYSWw2G6qqqtDQ0JDupiTdWF/r2rVrA+91yi0DAwO4du0aenp64PP50t0cIsoBOp0ORUVFmDJlCoxGY7qbQ0RJ5HQ6sW7dOiiKErTdbDYHBmAB/kFYiqLAarWGHTTGdiYfBzlRKjC2IKJEizW2kIQQIgXtIsprra2t2Lx5M6qqqrBz505YrdaI+zocDjQ3N2PLli2oq6uDzWZL+EyM9evXw2q1jnjcBQsWAABaWlqCkjdDNTc3w2634+DBgwltX6batGkT2tracnqmiGak1+pyubB+/XpUVlbiySefDPv8uro6OJ1OnDx5MhXNpSTr6emBy+WCTqdDaWkpCgsLodPpOMKbiOIihIDP50Nvby86OjqgqirKyspQVFSU7qYRUQpo/cSR4hxtENbTTz8Nq9U6agyVz+1MNIfDETTIif15SjTGFkSUSPHGFpwpQpRkdrsdDQ0NqKqqQktLy6j7V1dXo7S0FHV1dUlrU0dHB3bu3BnVviPd/K+vr4fdbk9Us/Lepk2bIiYZMklraytcLhdcLlfEfYaOpKPsd+PGDRgMBsyaNQs6nS7dzSGiHDFu3DhMmDABH374IW7cuIHy8vJ0N4mIUqCsrAxOpxMlJSUR96mqqkJVVRU2btyIdevWYdWqVSMO1srndiaaNuPFbrfD6XSmuTWUixhbEFEyxBpbsNA6URI5nU40NDTAbDZj7969UT+vqqoKGzZsSFq7SktLEzbTIdtHQsXCYrEk9fgXLlxI6vFjMdJrtdlsSZnBRJnJ6/Wiu7sbEyZMYNBCRAmn0+kwYcIEdHd3w+v1prs5RJQCWj8zmr612WxGS0sLrFYr6urqRhyUk2iZ2s5NmzYl7dhDcZATJQNjCyJKplhiCyZFiJJo8+bNAIAtW7bEnITYunVr0pZoGmm0U6zyKSmSbKkM8sbCbDZj+/btsNls6W4KpYDWkSgoKEhzS4goV2mfL0yKEFEk2ix3Lb7KVKloZyYNpCKKFWMLIkq2aGMLJkWIksRut8PlcsFsNsd983jFihUJbpVfImc8WK3WrLmZn8kcDkdIQUeiTMI1fokoWfj5QkSjqaqqQnV1NZxOZ0Yv35uKdjL2olzAv/1ElCzRfr4wKUKUJFonePXq1XEfY+XKlYlqTpDa2tqEHUurgUJj09zcnO4mEBERERFlrPr6egCZ329OZjs5kIqIiCgxmBQhSgJFUQJF6bRCdfFYvXp1Qpe60oylTcNVVVUlbZmvfNHQ0ACHw5HuZhARERERZSwthnG5XBndd05mOzM9IURERJQt9OluAFEuam9vD/x/LDU3zGYztm7dmogmpYzD4cC+ffuClugqKSkJeR0NDQ1ob2+HoihwuVw4efIkAH9H3+12o7OzE+3t7SgrK8PWrVsD19HlcmHfvn2B/1+4cAErVqyIeJ02bdqECxcuQFEUdHR04MiRI1AUBbt27UJnZyfcbjeOHTuG6upq1NfXj7lGSmtrK44ePQoAgeNv3LgRVVVVIfva7faQwGb58uVBM2+qq6sjFjSP9lonUnNzMxwOB1wuF1wuF44cOTJqUkxRFNjtdrjdbgD+n5vFYolYa2fozwwADh48CEVR0NTUhJKSErhcLqxZsybsjKdYrn+s52poaMCBAwdCjvHiiy+GvI66ujo4nU6YzWYoioKamho8+eSTI14nIiIiIhqZtnTvoUOHEjrQK9GS0U4OpCIiIkocJkWIkmDoOq/5NIuisbERhw8fxs6dO4OSCw0NDVi1ahX27NkT2G6z2VBdXR1UhLChoSEkMbF+/XrU1dXhxRdfhMvlwv79+4Nu+iuKgkceeQQulyvsTeeNGzfC5XIFzuNyudDa2ho2SVNXV4fHH3887uXFGhsbsXLlyqBjO51OrFu3DqtXrw5JbthstkC9mfXr18PhcODIkSNRnyvaa51I1dXVsFqt2LZtW1T7O51OOByOwDICmtbWVjzyyCNhr/fGjRvR3t6OhoYGWK1WKIqC7373u3jyySehKAqWL1+Otra2QCJNE+v1j/Vc27dvx/bt29HQ0AC73T5ioqOlpQV1dXVQFAV79+6NmJQhIiIiouhpyYZjx46luykjGq2dqRxIFeugoXBiHeQ01vNrA+HKy8sDg5fcbjfWrFkDh8OB6urqsM9Px6AxIiLKTkyKECXB0HVe86XeRmNjI3bv3o2DBw+G3Izfvn07Vq1ahc2bN6OlpQWAf9ktrRChw+FAY2Nj2E71li1bUFdXF5jZMbyzbzab8eijj2L37t1wuVwh59bOU1VVBafTiX379oXtFG/fvh1utxubN2/Gnj17Yh7R1draiiVLloQ8r6qqCo8//jg2b96MqqqqQBJkLGK91omkXcv9+/ejra1t1P2HJ7E0WiIk3PXWzmG32wOzNrTkg9lsRk1NTcjrjvf6x3OuLVu2wG63o7Ozc8TXvnjxYthsNiZEKGpaIs1sNqOsrAyA/+aBlmivrKwM2VZfX5+Qz5Vky+XXRkREqaMtLZzpxcZHameqB1LFOmhouHgGOY3l/K2trdi/f3/YwUdaHBQuzknXoDGiTJXL/e9cfm2UOkyKECXB0Bv7HR0dOT9bxOVyYffu3diwYUPEjmZ9fX1gyvfQG9dDa6aEu07aDeVInV8AWLJkCQD/yKBIf+S05NTatWsjvo6tW7eira0NDQ0NOHjwYMT9wnE4HDhw4ADMZnPIjXktSLDb7WP+IzyWa51IQ0dfjWTjxo0RH6utrYXVao14vUtLS+F0OkNeZ7gAaazXP5ZzacmStra2sIm4oZgQoVg4nU7s3Lkz6MaCNmOpuro66P2ozWo6f/58Opoas1x+bURElDpaH7SjoyO9DRlFpHamciBVos4VzyCnsZx/27ZtePHFF8O2RYvXhkvnoDGiTJXL/e9cfm2UOiy0TpQEQztiQ2eN5KrGxkYAwMqVKyPus3jxYgDAoUOHwj4+0nM1o91gjuZaj3QD22q1oqamBi6XC3a7fdRjDeV2u6EoCpxOZ8RjJ2JEWyKudSqNlhCM5npHk9hJ1PWPNomkJde0+jbDtba2xr0MG+WvmpqaiO+boQlkwP+7tWPHjlFnLGWKXH5tRESUetkyG394Ox0OB7Zt2xa2NsjQgTyJkKhzRTvIKRHnVxQlUAsykpqamqDvox00ps14IcoXudz/zuXXRqnDpAhREmg3pYGxT+2OdJM3k2hr5Q593cNpHdRI6+qONpV5pMcTORNHm3USa0Jhx44d2LlzZ8i0co1WcHusEnGtM0l5eTmAka93NNPcE3X9o51Sr9VWefrpp8M+vn///owu/kmZR1GUqJLDQ5nN5pBOfybK5ddGRESppdW0yPSZ+JHamaqBVIk8V7yDnOI5v3auzZs3R+y7r1mzJqhN2TZojCgVcrn/ncuvjVKLy2cRJYHZbA7UsHA4HHGPGNcK2kWz1ms6aZ3ZXbt2jbis0pYtWyLedB5ttFeqAh+tfRcuXIjpeWazOfBz1oq5Hz16NHC8RAU3ibjWmUT7uY90vaP52Sfq+sfyPrPZbGhqagqZFeJyuQLJNaJojbYUWzbL5ddGRESppY30HWmAUCaI1M4dO3ZgzZo1EeNDs9mcsLghVecaOshp6FJY8Z5/+/btaGhowPLly1FVVYUVK1Zg5cqVgQFHw1cPyLVBY0SJkMv971x+bZRaTIoQJYnNZkNDQwMOHDgQd1LD5XJlfE2CoSN4Nm7cmPGjtpKptbUVTU1NsFqtqK+vD5q1cPjw4THP+uG1Hlmyr/9wWlLkqaeeCgr29u3bN+IyA0ThxPtZP3SN7+bm5sD/3W43ysvLg25OOBwONDU1weVyYcWKFVi7dm1gxKQWXIRbMzyaY49kLK/NbrfDbrfD6XTCbDbj0UcfDbSxtbUVmzdvBuCfvVVfXx/361MUJfD54Xa74XK5sHHjxoz/G0xElG+05Y8yfUZupHamaiBVKs8VaZBTvOe32WywWq1oamqC0+mE0+nE7t27AfhnpezYsSMoDsq1QWNEicDYIhRjCxqOSRGiJLHZbGhubg5MJY6nWJ7dbo+4HFCmyLUb80ePHgUAlJWVxfS8hoYG2O12bNmyJaE/M7vdHliqKdeuNXCn+GSs13u4ZF3/kQwtuO50OgMdnM7Ozpz8WVFmq6urw2OPPRaUoGtsbMSmTZsChQarq6vR0tKCuro6HD58GCtXrgzqyG/atAl1dXUhRUijOXay2Gw22Gw2rFq1KiTwqK2txYYNG4KCqHhen8vlQl1dHfbu3Rv4PQ63jYiI0mvoAJdMrt02WjtTOZAn1YOGEnV+rc+iKAocDgeOHj2Kw4cPo62tDYcPH0ZLSwusVisHjRElCWMLxhb5gDVFiJJo586dAICmpqaY60m4XC643e6sGM2iFbtrb29Pc0vGTptSHcsalQ6HI5C8iHRDfvjP3+l0xjU6K5euNXAnaFyzZk3cx0jl9R9OmxGiraHMAuuUDg0NDSgtLQ15723duhWHDx9Ga2tr0PbS0lJYrdaQZP2OHTvgdDoDa3PHc+xksdlsEYujDn8dsbw+wP8aV6xYERSgWK1WrFixAk1NTQl6BURENFb79+8HAGzYsCHNLRnZSO1saGjA5s2bYbPZsGfPnoTNeLHb7SF922Sda7hIg5ziOb+iKEF9C222ydatW9HS0oI9e/ZAUZRAYXcmQYgSj7EFY4t8waQIURJVVVVh+/btUBQF69ati+m5DQ0NEafiZRqtnfv27RtxP0VRQv5gpNpIySmXywWHwxH2D95ItD/cI90MHx6kuFyusG0Zvk1RlKB6K9l0rbV2jOTAgQOoqqoaUyIhkdc/VlVVVbBarYGkCAusUzrY7faI7/9Ine9wdZy02U9PP/30mI6dDNpn8tAiroqiRFwmI9rXp41ADVcHaOXKlTmTgCYiynaKomD37t0wm80ZvUzpSO1M5UCeVJ4r3CCneM9//PjxkILtQ1VXV2PLli1BNzNzbdAYUboxtgjF2CI3MSlClGQ2mw07d+6E0+lEXV3dqB1NRVGwadMm1NfXR5wlYrfbA6Njki2aG8dWqxXbt29HW1tbxGw74F/nde3atYlsHoDo2ji0DZFoSYQ9e/aEfdztdofdrv2cIrWjtbU1ZIpkR0dH0Mgm7UZ6uJv3Q/dL1bWO9FqjfRzwdxJGut7Nzc1QFCUwoypeibj+Y6EFeg0NDSywTimn3YgI11EHAIvFEtMNDm0pCkVREn7ssTCbzaiurg4KXA4cOBDz0pRDXx9w5waKttTl0C/Av/44ERGln7bO+86dOzN6dsBI7UzlQKpknmu4cIOc4j1/V1fXiDEO4I+bhl7bbBs0RpTJGFswtsgnTIoQpUBtbS0OHjyI0tJSrFq1Cg0NDSHrp7pcLjQ3N2PdunXYuHFjxNHm2nThoR+siTa0Izpap1Rjs9mwfft2bN68OeyUx8bGRqxcuTIk0aMV5Iv0x0/74zLSH0ftsWj+gK5cuTLsddu0aROOHTuGPXv2RExGRWqrzWaD2WzGU089FfKYw+GAy+XCY489BuBOgOB0OoPOM7SgoGb4PkP3jedax2K0n8tojwP+P/hr1qwJe72196+2HnA40f5cE3H9Y3kPhTu/9priqR1ENBbakhXZdux42Gy2oFGs58+fH/ONMS0oq66uDqwxPPyLiIgSSxtcE80gG0VRsH79ejgcDuzcuXPEGbmJHjiW6HameiDVWM8FxD/IKd7zjxs3DgBGTF5oRY+HniudA/SIcgljC8YW+YSF1olSxGq1Ys+ePXA6ndi/fz+2bdsGl8sV+NDUlmwaXqRpOC2j7XK5ErpMj5YU6OjoCOq8NjU14amnngq08+DBgxGPYbPZUF1djebmZtjt9qCbzsNnvmizZrRzrVu3DqWlpdi+fTuqq6vhdDqxefPmwB9ORVGwfPlylJaWBtqgnUf7I2a323HgwAGsXr0a27dvD9tG7dppAVNJSQk6OzuxZMmSiEW9Rmur2WzGiy++iF27dmHz5s1YvHgxSkpKAABLliwJzCTYvn07nnrqKezfvz9kaTSz2Yw9e/agoaEB69evh9VqDRQkHOu1jsVorzXS4y0tLUEdiMrKysAffLPZjMbGRlgsFrjdbnR2dsJqtUZ8L61atSrofVhXV4fS0lJUVlaG/RmN5frHeq5IbDYb3G53Ro9cpNy0ePFiAJETerHWpjp27BjMZjPMZnPCjz1W2mjTffv2Ye3atXHNzBr6+gAEFT8kIqLU0AbXdHZ2RtzH5XKhtbU1EIe0tLSMWJx2aJ2JqqqqhNx4SnQ7bTYbnnrqKTz11FOora0N+hs6dCCPNvCptrYWTqcz6LXYbDbY7XY0NTUFZreHG0iViHMB/kFOixcvDjv4Z6RBTvGeX4tvOzs7w57T6XTiqaeewt69e0POB/hn6jz++OMhM1QSMWiMKB8wtogNY4vsJgkhRLobQUSUbNrIrZMnT6a7KZSD7HY7Fi9ePGKwnq36+vpw9uxZVFRUwGQypbs5eUdLCNfU1ERM1G3atAkXLlwIm1RfsGABtm/fHnRTYf369ejo6AjZXzvXli1bAsnEWI+d6Nc2XENDAw4cOIDHHnssYtI4ltcH+G+UtLW1hU3UNjQ0REyyU+Lwc4Yo92kDnobfKDKbzSFLqbhcLlitVlRWVmLNmjVR155bv349XC7XiDO/091ORVGwa9cuHD58OGQgj/Z8LdlQVlaGrVu3hryWoQO8RhpINdZzNTY2BgYSuVwu7Nu3L2SQU6S/xfGeH/DfoNy6dSscDkdglrf2XAAj1t3UVl/QfjaasQwao8Ti3/z0YmwRjLFFbor6c0YQEeWBdevWifnz56e7GZSjtm3blu4mJE1vb684duyY6O3tTXdT8lJHR4eYP3++WLdu3Yj7PPLII2Lfvn1B27dt2xb2eevWrRP333+/OHToUND2b3zjGyH7x3rsWETz2oZrb28X8+fPF//0T/8UcZ9YXp/mi1/8onjqqaeCth04cCDkGJQc/JwhIiLKD/ybn16MLYIxtshN0X7OcKYIEeUFzhShZHG5XHA4HDm7PihHc6VHQ0MD3G43jh07FhitWl1dDavVGnFZEG39ba1IYaT91q9fD8A/alJRFLhcrhH3j+XYyXptQ61atQo7d+6MODMrntcHBL9GrU25OPsrE/FzhoiIKD/wb356MLaIjLFF7on2c4Y1RYiIiKLkcDhCavk0Nzdjy5YtaWoR5ap4plWPtJxEOLHUpYr12CMZ65TxmpqaqAKKWOtuJfI1EhERERFlCsYWkTG2yF9yuhtARESUDRobG7F+/Xo0NzcHtmkjRFhgnSg1FEVBeXl5uptBRERERERZjrFFfmNShIjygjaN0ul0prkllK2WLFkCq9UaKAypKAoaGxtzdtksokzgdDoDU88B4MCBA1i9enUaW0RERERERNmIsQUNxeWziCinrVq1Ch0dHVAUBQCwbt06lJaWYvv27TFPf6T8VltbC5fLhX379gW27dixI40tIopPR0dHupsQtf3796OtrQ1bt26FoigoLS0ddWZWNr0+IiIiIqJslk19b8YWNBQLrRMREVFELIaYO5xOJ3bt2oW2tjYA/vVz165dm9EJYkVRsGvXrkCBwvr6+oj7ZuPrIz9+zhAREeUH/s3PHdnY92ZskR+i/ZxhUoSIiIgiYuBCRMnGzxkiIqL8wL/5RJRs0X7OsKYIERERERERERERERHlBSZFiIiIiIiIiIiIiIgoLzApQkREREREREREREREeYFJESIiIiIiIiIiIiIiygtMihARERERERERERERUV5gUoSIiIiIiIiIiIiIiPICkyJERERERERERERERJQXmBQhIiIiIiIiIiIiIqK8wKQIERERERERERERERHlBSZFiIiIaMxUVaS7CTHLxjYTEREREeW6bOynZ2ObifKZPt0NICIiouwnyxKe+Y0X19zZEQxMsUj48icS2w1qbGxEZ2dn4Hur1Yr6+no0NzejtrYWVqsVAKAoCurq6mCz2VBfX5/QNoTjcrmwefNmuFwuWK1WtLS0JPV8TqcTdrsd7e3tKCsrAwBYLBbU19fDarXC4XBAURTU1tYm5fwjvd5UX3siIiIiih1jC8YWGsYWlCxMihAREVFCXHMLXL6VHYFLotXV1eGxxx4L6oy7XC5s2rQJbW1tQds7Ojrgcrlw9OjRlLRN67yvX78eHR0dST1XY2Mj2trasGXLFmzfvj3osebmZlitVmzbtg1btmxJWhtGer2pvvZEREREFB/GFowtGFtQMjEpQkRERDQGzc3NKCsrCxmdZLVasXXrVrS1tYVsP3nyZCqbGDhvMgOXuro6AMDBgwfDPl5fX4/GxkYoipK0NgwV7vWm69oTEREREUWDsYUfYwtKNtYUISIiIhoDh8MRmL4+nNVqRU1NTYpblHrNzc1wOp3YuXPniPtt3bo14rUiIiIiIsp3jC0YW1BqMClCRERENEaHDx+O+NjKlStT2JI7XC5Xys7T1NSE6urqqIKSfAjkiIiIiIjixdiCsQUlH5fPIiIiIhqD2tpaNDQ0oKGhAVu2bIHZbA563GazBf7vcrnQ0NCA9vb2oEJ9TqcT27Ztg8vlwooVK7Bjxw7Y7XaYzWYcOnQoMF1+OJfLhcbGRixZsiRQ/M9sNqO0tBT79+/HmjVrRi06qCgKmpqaYLVa4Xa74XK5sHHjRlRVVUX1+vft2wcAqK6ujmr/NWvWBIIqu90Ou90Op9MJs9mMRx99NPA6W1tbsXnz5sCx9+zZEziG9pySkhIA/uBwtPNHuvZDxXNcIiIiIqJEYWzB2IJSg0kRIiIiojGw2WxobW0NdMKtViuqq6tRXV0ddi3gPXv2hBTqq6qqChTw6+zshN1uR319feD4y5cvh8ViCWwD/AFHXV0ddu7cGehcr1+/HlarFdu3b4fVah11dJXL5UJdXR327t0bCFTCbRvJsWPHAq8tGlVVVYHj2mw22Gw2rFq1KiQ4q62txYYNG1BeXh4U/G3atAkWiyWo2GJjYyOAkYOnSNd+rMclIiIiIkoUxhaMLSg1uHwWEVEKCJ8Xwucb/PKG+fJBCJHuZhJRnPbs2YPt27ejqqoKLpcLdrsdmzdvxvLly+F0OkP2j9TJLykpgcPhCAl4Fi9ejAMHDgRts9vtUBQlqFNdW1sb2F5VVRUysmy4hoYGrFixIihAsVqtWLFiBZqamkZ93QACQcBo5xqJzWaDw+GI+JjGbrejra0NW7ZsCdqnra0tMKpsNOGufSKOS0RElEpCCAihQqiDMYbqg1DV4C8hGGMQZSHGFowtKPmYFCEiSgFJp0f/kZfR95tfoe93B9DnaEPf4RfQ99pB9B95BQNHX4Png6PwXjoHn/smRH9f2OMIIe4kVlQ1xa+CiEZis9nQ0tKCkydPYs+ePdiwYUNgxJWiKFEdw2KxwGw2h3Suw3W2tSnt4faLZs1fRVHgcDiwZMmSkMdWrlyJ9vb2qNpcWloaOF68tODEbrcHtc9isQTt19TUhJqampAgqbKyEmvWrIn7/Mk6LhERUdIIAUmS0fvyL9D76n9BknWQZBmeax/Cc90Fz82L8N66DF/HdXi7bsPX2wV1oB9C9YU5lAgkUogoMzC2YGxBycXls4iIUqT/nd9BvXk1+ifIMqTCYkhFJZALiyEVjfP/v2hwW9E4yOMnQ54wBbKpKPA04fMCkgxJZt6bKF20Ke4rV67E+vXrsWvXrrDr9oajBQKjqaqqCuroA3eCh2impmuBiTb6bLjhI5siqayshMPhiKn44vCgy2w2o7q6Gna7PRDEHDhwIGgkl6IoUBQlbBD35JNPRn3u4ZJ1XCIiomQbOP4m+l97AQBg+uinIBUWo//CydGfKMmQ9Ab/l8EE2VgAucgM45RZgV1UVQASAAHIspSkV0BE0WBsMTLGFhQPJkWIiDKVqkJ0d0J0d2K0MVuSqQjyhCnQTZgy+O9U6KbMhDxhCiSdDgAgfD5AkpgsIUqwxsbGiEGJFsBoa+NGI9qp4qtXr0ZTUxMcDkdgmvv+/fuxYcOGqJ6vBUjh1ieOxdq1a7F79244HI6gdYkjaW1tDRsk2Gw2bN68ORDUnD9/PuhaaFPph4/wGqtkHZeIiCiVJJ0OiHapLKFCePohPP1Abxd8AHTmvqCkiCxLuHLbCwHAZJBQaJRQYJAgSf4EiRACAoAsMWFClEiMLRhbUGowKUJElANEXw98l87Bd+lc8AOy7E+STJ7h/5oyE7ppVuhKJ/qf5/NC0vFPAdFYjBaUVFZWxjTSKVpmsxmrV69Ga2srDh06BABYsmRJVMEDgKDih2NhtVqxZcsWNDU1hZ12P9zRo0fDBkratn379mHt2rUhU+9jmb4fi2Qdl4iIKKVk3ZieLhlMEEIEkh4AcP6GB70DwYmWgsEESbFJRolJRkmhjEKjP1nCRAnR2DG2YGxBqcE7YUREuUxVod64AvXGFXiOvxXYLBUWQ2+dB335POhnL4BuykxIkuyfTSLLQcEQEY2so6MjaGr2cIcPH8Zjjz2W8PNqo7jGMhJrw4YNsNvtYYOdhoYGbN++Parj1NfX48CBA9i8eTNaWloi7ud0OsOuM6yx2Wx4+umnYbFYwrappqYmYtHEkX4Go0nWcYmIiFJGjmGmSLinG03+5w+JA/o9ocfr9wj0ewTc3XfmsssSUGySMW7wy1woocgkB5IjqiogSWCMQRQFxhaMLSg1mBQhIspDorcbnvffhef9d/0bjCboy+ZAX34XDLPmQzd9FiSdzl+IUWKShKIzxZI975NEt/XQoUM4f/48Nm7cGDQtu7m5GaWlpWGDi3DFA91ud9TbrVYrNm/eDLPZjNLS0sB5RxpNNfwYW7duxeHDh9Hc3BwUKLS2tsYcELW0tKCxsRGrVq3Cli1bQp7f2toKl8s14mgzm80Gu90Ot9sd9vEdO3agrq4uZFkBp9MZdr3kSAUah2+P9bhEREQZRx4c4BQnyWgK+t7rE1CjzLGoAujsVdHZeydRIgEoKpD8iZJC/4ySkkJ/okQVgrNJaFSMLRhbMLagZJKEGMNQAiIiilrHv3wvtkLr6aQ3QD9jNvTld0E/az70ZXMg6Q1MkuShvr4+nD17FhUVFTCZTBH3U1WRdUU4E9VmbdSTy+XCvn370NnZCcAfbAyfcu5yudDY2IjDhw9DURTU1NQEgp3h29euXQur1Rq0vbq6GjabLRAUrF+/PuwopJqaGuzYsQNmsznsOdeuXRtYKxjwr10M3Fn7trq6OqqCiuE4nU7s2rULnZ2dKCkpCQRSa9asieqYq1atws6dO0fct7GxEZ2dnbBarTCbzbBarYHXE+n1Dr+W2rUfep6RjkvJE+3nDBER3SFUFZ6Tb6O7ZTcgyRj/nf8N1etB9zsvxnW8wvn3Q1cyMdDP7+5T8cbpvkQ2GbIElBbJGD9Oh4klOhQVyFxyK88wthgdY4tgjC0oVtF+zjApQkSUIlmVFBlO1kE3vRyGeYthXLgMuknTIFTVX7idAUxO483KzNXQ0ACr1RoUGCmKgvb2djQ1NQHAiNPNM9VIxSUpN/FzhogodkFJEb0B4//7k1A9A+h+96W4jle8+BOQTUX+YwuBW10q2s/3J7LJIYx6CeOL/UmSCSU6GHT+uiQAl9rKVfybn7kYW1CuiPZzhstnERHBP6pDmx4uSf7p3tk2MiWpVB98F8/Cd/Es+l79JeTxk2GYfw+MC5dCN7MCAAMXolRyOBxob28PWZfXbDajuroae/fuxfLly6EoStCU+0ynKArKy8vT3QwiIqLsohsssj6GMa+SsSDwfwGgz6NG3jlBBrwCVzt8uNrhX/ZrnEnyJ0jG6WAu4lJbRKnC2ILyEZMiRJTThBDwqYAsh07JHvAIdPUBSrdAR49Abz8w4PVv7/f4/9/vCf5eFf5YQwiBz31UjznT5TS9svRSb19H/+8Pov/3B6ErmwPzn94ZecHRXUTppwUrmR60OJ1O7N+/PzB668CBA1i9enWaW0VERJRdJJ3/1o4QcSYydHpIsi5oU7gi68nW1SfQ1eeF64YXsgRYimVMLNFjSqkOeh0TJETpwtiCchGTIkSU9YTwz/IYOrtDVQU6uoHrHQLXOwTcXQJKj0BXL9DZK9DZA3jir0MIwJ8wIcBQfheEqkKS7ySIhHcAkqGACRKiJKmurkZpaWlIEUPNpk2bsGXLljS0LDb79+9HW1sbtm7dCkVRgoo6EhERUZTksc0UkYcVWZclKS1JkaFUAdzqUnGrawCnrgATxukw1eKvRaJFFowxiBKDsQXlIyZFiCiraAkQ3WDyo98jcOmmwDW3wE1F4IYicLND4HYXAsthUXIZKu/3rzk2SJIkdB9/DZAkGMZPg37idOgKSyCECknKz5k1RMmwZ88etLa2Btb/1bhcrpBih5lq48aNAIDm5mYACBuEERER0cikwPJZ8c0UkYyFIdvSnRQZSgjgZqcPNzt90MvApFIdppXqUVqs4yAsogRhbEH5hkkRIspYwxMgvf0CF28IXLwpcPGmiss3/ckPSh/ZMgn6qWWB74UQUHs7IQZ6AQADV85g4MoZyKZxMEwqg2HSTEh6AxMkRAlSW1uL2tradDcjbmazmYUPiYiIxmpwpogYw0wRIURQYiGTkiJDeVXgym0frtz2ocAgYUqpDtMsehQVcHktorFibEH5hEkRIsoYQ5Mgqipw+ZbA6csCrusqLt0Q6OhJdwtpOMPCpSFLZ3lvXQnZT+3rQv+FE+i/eBJ6yxQYJlmhM08MPM6RXUREREREcRqsKRL/TBGTfzrG0KSINzOTIkP1ewRcN/w1SMaZJEwp1WOqRQ+jXgpJ8hAREQ3FpAgRpc3QJIhP9S+DdeaywNkrKs5fExjwpruFNBpjmKWzPLdDkyIBQsB7+yq8t69CMphgmDQThsllkIyFIckVIiIiIiIaXWD5LDW+oomywQQMyR94vCLe8iRp4y/S7sGZqx5MLNGhbKIelmIdZ48QEVFYTIoQUUqpqoAk+W+eX+8QOH5e4MxlFeevC3iYBMkqsnkC9NPLA98LIaD2dUP0RzelR3j6MHD5NAYun4auZAIMU2dBXzoFgODSWkRERERE0dKNbfksqaAwqP/d54lvxkmm0OqPFBdImDnRgKmlusA4Ls4eISIigEkRIkoBnyoCs0HOXBY4fl7FyQsqOrrT3TIaC8PCe8MsnXU5rmP5Om/B13kLUkERjFNnwTCpDJBkBi1ERERERKORtZki8SUz5CGF1oUQ6MvQeiKx6u4XeP/SAM5cBWaM12PmRAOMenBpLSIiYlKEiJJDS4R0991Jgpy+xCWxcol/6aw730uSBO9IS2dFQfT3oP/8cfRfPAXjZCsMU2dDNhgZuBARERFRVvOp/iWpZAmQ5dB+bb9HoLvP/++rLx/Eq68cRPmsOXC7OyAAbPjzrZhf5h+M5Ha78dd//dcwq/34m4oiSMNqirg7u7D32QO41aEAADo6u3Fb6cQ319nwxF47xptLsL5uDe5dOA/uzi689upv8VRzM7797W/j3qVLM7bIery8PuD8DS9cN72YWqqDdZIBRQWsO0JElM+YFCGihNESIf0DAu+dVfHeWRXnrmbferQ0OqmkFPqZFYHvhRBQ+3ug9iVo+o/Pg4ErZzBw9Sz0E2bAOK0CusJxEELl0lpERERElFFU4Y95dEOSHT5VoLcf6OoV6Oz1/9vV66990d0HdPfd+b6nD/ANTvI4fqQFx15/Bl/6i5+hG4BhEnDW+SJqaz6FL3/2fpw5cwbLly/Hiy++iIfuuwdA0Z2ZIkKFu7MLT+y145vrbLCUjAu057kXf4tPfPUbuGfBXDx38nfY8+yBwGMWiwXPPPMMli1bBiFEziVFNEIAV9w+XHH7MLFEh/JJepiLWHeEiCgfMSlCRGOiqgKyLMHr888IefeMig8uikCnnmK37mfPY3xhAdY9UIl7ZkxGR28/3r54HXuPHMNffXIp7pkxOarjvHLqAl45fQGzJ5ih9PUDADZ9fGlC2mhcsHRYgkLEvXTWiISA9+ZFeG9ehM48CQUz74KuuJSjuoiIiIgo5YQQUFVAlu/UpnB3CVy+JXDltsDV2wLX3AJKj0DfQOzH7+txY//e/wd/0XgyaHtF1SN46Zm/wdy5c/E//+f/BADY7fbA41KgpoiKZ1/4DfY+24r1X1wTlBT5wiMfh6VkHC5fv4lf/Ogf8O7JU/5jV8zBH//V39w5liTlbFJkKK3uSGmRjPJJBkwoYXKEiCifMClCRHFRVQFIwOnLAu+c9uH4eZVLYyVIR18//st5Bj9543hgW6nJiD1rPx11QuQX7afx7NHT2PuVTwe2vXLqAr6455d4dv3nxtxGQ+V9gEBg+SxJkse8dNZofMoN9Cg3oCudjIKZ86ErKmFyhIiIiIiSwqcKSLiz1FVvv8CVWwKXB5MfWgIkkTHQsdd/DsvkCpiKLCGPVT7wh9i1axcee+yx0Cfq7tQUmT1zOgCgoyvyDO6HPrIUD33EP1hKb5kS8ng+JEU0HT0qjp7vR2mRjLnTDCgp1DHGICLKA0yKEFHUtFkhXb0CR06qeOMDH4ulJ8E9MyZj88eX4r3L1wEAs8ab8fnFc6N+fkdvP/7yuVfxzrf+KGj7g/PK8HfPv4a9R45h3fLKuNsnFZuhL5sbFCio/T1Qe7viPmYsfB3X0dNxHXrLVBhn3jW4rBYDFyIiIiKKn7YUsCoErt0WuHhD4Krbn/y4ctu/5FWynTjynygsHh/2McvkOXjpmbfgdrthsViCH5Tv1BR56CNLcf6lZ8Iew93ZhcV3VQRtk4yFIX3pXCm0HouOHhVvnenHZLMOc6YaUGDwb2eMQUSUm5gUIaJRaQHC2SsCvz/hxQmXgJp//eSUenBeGR6cVxbXc59tP43ZE8woLSwIeeyLS+biJ2NMihgW3Bv0vRAqPMlYOmsUXvdVeN1XoZ8wHQUz74JUUMTkSBpl47XPxjYTERFRYvhUAVny3/S+1SnwwUUVpy6pOHslvqWvEuHyubewaPmXwj5mmexPZpw5cwbLli0LeiywfNYIaxj/r5/6EyXLFy8I2i4bTf5iG4N9IiEEBrz5G+xdV3y40enD9PF6zJ5igF5mfzEdsrGfno1tJspnTIoQUVhisDp6nwd4430Vb5z04WZnmhtFUflF+2lYwiREAP+sk3cv3UBHb3/YpEk0jJX3BQVOkiTDeyu5S2eNxHvrMry3rkA/cQYKyuYDeiM7o2kgSRKOX+hHT392FBQqKpCxqCy+34HROJ1O2O12tLe3o6zMn9y0WCyor6+H1WqFw+GAoiiora1NyvlH4nA40NTUBJfLhRUrVuDJJ58c9TmKoqCurg42mw319fUpaGVqjfX1uVwubN68GS6XC1arFS0tLXG1I93vm5FeR66/B4goP6iDo7pkWUJPv8CpiypOXRI4c1mFO0Nmv/f1uMMunTVUuKRIYPksEb4f5u7swo9b9uOn//gdvHXsfZy9cBmvvP42AMAw+SjOXr6O73znO7BYLHmdENEIAVy65cVVtxfWSQZYJ+ohSZw1kkqMLe5Idx9xJIwtQjG28MuG2IJJESIKoi2RdbsL+M17PrxzRoXXl+5WUSzeuXgdX4iw3NbsCWYAwLnbCu4pjK4+yVBS0Tjoy+cNKbAOqP29UHvTnTEbLMh++zKMUytgnD4HkKSgdlLy9fSr6OrLlkA6OQFWY2Mj2trasGXLFmzfvj3osebmZlitVmzbtg1btmxJyvlHU11djZaWFtTV1UX9nI6ODrhcLhw9ejSJLQuvsbERW7duTeo5xvr6tE7++vXr0dHREdcxMuF9M9LrSOd7gIgoXkL4Z7frZAker8C5qwKnLvkTIdduC2RLj0VjKioFANy6dSv0QZ3eP6htSFLE3dmFvc8ewNkLl3Fb6cQvfvQPqCibjpYXfoN3T57C+ro1AICihR/Fu++fwX333Yc333wTsrEkJa8nG/hU4Nw1Dy7d8mL2FAOmWXQQAIuxpwhji8zoI46EsUUoxhZ+2RBbMClCRADuLJF1+ZbAq+95cdwlILKl/5GDzt1S8MrpC0Hf/9UnlkY1u6Ojb2DU/c7dUqIu2j6UYf49CFRXR/qWzopIVTFw+TQ8Ny6gYOZ8GCbNhBAqkyOUElowcPDgwbCP19fXo7GxEYqipLJZYZWWlka9r9VqxcmTJ5PYmshcLlfSz5Go12e1WuMKXDLtfRPudaTzPUBEFAsh/DGMPBjXnLwgcPqSCtd1gRFWlsp6kqzzT28YEsBZSsbhL//kywCAl3//Nv7y+z/E+rrV+Ok//k3wc42FWLZsGZYtW4b6+nr8790/S2nbs8GAV+D9SwO4cFPCnKlGTCxhMXZKvkzrI46EscUdjC2CZXJswaQIUZ7TkiFnLgv85qgXZ68wE5Ju524pePfS9aC6H+9euo6H/s9/4uX/90txL3sFAKUm/3Nv9/bH9fywS2fdTt/SWZEITz/6zh3FwPXzMJVXQVdsZuBCSdXc3Ayn0xmx86nZunUr2traUtSq7Nba2orOznTPQksuvm+IiBJDm+1+vUPg3dMqjp5TcSvH/oT09fhvKk2YMCH0QZ0OgICIsHzWQx9ZiqWVd6H84S9j57e/EZglAgCSwQgA+NSnPoWNGzfiif/v/ya87bmip1+g/Xw/LMUy5s8wwmTgklqUHOwjJh5jizv4vvHj0FmiPOVTBYQQaD+n4oe/8OAnLzAhkin2fuXT+Pyw5a/umTEZd8+YhM3PvZqmVgFSYTH0sxZAkocsnTXQB7Un/SNTIlG7O9Bz3IG+c+2AzxuolUOUSC6XC01NTaiurobVah11/5qamhS0Kru5XC5s27Yt3c1IKr5viIjGxjdYI+R2l8CrR1U8+ZwHTz7nxatHcy8hMipZBwhErCkC+GeOfOGRj2Hz938Id2cXAEAyFARu6mvJljfffCvpzc127m4Vb5zqw4Wb3sHZSYwxKHHYR0w8xhah+L7hTBGivKPNDDnpEnjhLS+ux7dEIaXBg/PK8M1f/GZMx+jo888QGR/HbBPDXXcHZogA/qWzvJm0dNYIPDcuwHP7CgrKFsA42coltSih9u3bB8C/pm401qxZE3bqdnNzc+D/brcb5eXlsNlsgW1OpxPbtm0LFDLcsWMH7HY7zGYzDh06BIvFgu3bt0NRFNjtdgDA0aNHYbVaI66d63Q64XA4AucEELSvy+VCQ0MD2tvbgwrkjdaWSOd0uVzYt28fLBZL2PMB/lFc+/fvBwC0t7dj06ZNABD2mKNds6HFHx999FGsWbMGDocDDocDNpsNVVVVYV9fLO2N11jeN3a7HXa7HU6nE2azGY8++migXa2trdi8eXPg2Hv27AkcQ3tOSYl/vfiVK1eOev5I74Gh4jkuEVE8tBkhfQMCb59W8c4pFRdv5s4NacvkCty+fjbsY33d/loic+bMCXlM0ukBBC+fFc6FK9cBAK+8/ja+8MjHIRkL75zbYgEAXL95E+PL4mh8nlEFcOaqB9c7fFgw04iiAs4aocRgbMHYIh6MLWLHpAhRntCSIWevCLzwpjengod8oSUy3r10Pa56IGNlXBS6dJbn9tWUtyNuPi/6P3TCe+sKTBWLAYOJgQslxLFjxwAgqhE5AFBVVYWqqqqgbXV1dXjsscdQW1sb2NbY2IhNmzbhySefDDxPK1bX2dkJu92O+vp6AIDNZsPy5ctRUlICi8US2A4Ay5cvD9kGAIcPH8aaNWuCttvtdtTV1QU6p1arFXv27AkpkBdNW8Kds7m5OajYX2NjY9D5AKC2tha1tbVYv349AARe/3DRXDOt+OOqVavQ2dkJh8OB+vp62O127N+/H7W1tWFfXyztjddY3jc2mw02mw2rVq0KCehqa2uxYcOGkCBu06ZNgeB26OsBRg6eIr0HxnpcIqJoaXVCIAGnLwu88b4XJ1y5WSNk2qyl6O9xh31MS5YsW7Ys9EGdDgAgVBXlD38ZDz5wb0jtEABwnjoHADh30b/8rWw0BR47c+YMAOCuRUvjbX5e6uxT8eaZPpRP0qN8sgEAC7HT2DC2YGwRD8YWseMwWaIcpw5OK790U+BfWz3Y+zwTIpnsr557Fd9rey3sY4F6ID0j1wOZPd6Mc7fCL2mlPXf2BHNM7ZIKCqGvWBi8dJanH2q3O6bjZAJf5010t/8OnmsfDgbZORhRU0ppnTmzObbfK01DQwNKS0uDOuCAf9TQ4cOH0draGrS9pKQEDocjZP/Fixdj9+7dYbcfOHAg5LxWqzVkX5vNBkVRAh3PofuGM1Jbhp/T4XDAbrcHRo8BwMaNG+F0OkNe42hivWZWqxUHDhwIdORbWlqCAqJwry+R7Q1nrO8bwP/zGtq+4Y9p7HY72trasGXLlqB92traAqPKRhPuGiXiuEREkdxZHgs4+LYPjc/4l/x1fpibCREAqKh6JOJMEfe1M1i1alXYxyTZnxRxd3QElsYKp3LeLADA7JnT/M8zmgJLP73wwguYM2cOjIXRF0wmPyGAD6978ebpPnT3qVxOi8aEsQVji3gwtogdkyJEOUrriN1QBH560INdv2bNkGzwXPvpiAmNc7f925fOHHmWyN0zJgWWyYp0jFhnmhjuWgJpcAQakF1LZ4Wl+tDvOoGeE7+H6O9l4EJjUlrqv3mgKPHV17Hb7SEdcM2KFSvQ1NQUtM1iscBsNod0JK1Wa8Tt4dqmtXu46upqPP3001G1faS2DGe1WkPWuNU67eGm/I8k1mumnV87XzTBQiLbG85Y3zfAneBEW9JAO562BIqmqakJNTU1Ia+7srISa9asQbySdVwiym9aMuTDqwJ7n/fgif/04DdHVXT2pLlhKVD5wB+ir/s2bl87E/LY8TdasHHjxvBPHOynW0rGYf0XV4edJQIAN90KxhUV4guPfBzA4EwRIeB2u/Hzn/8c3//Hf4THl5jXMhZvHH4JP/i7b2DXE98N/BurV55/Fj/4u28EfXUq7sQ3doiefoG3zvTj9FUPVFVAZYxBcWBswdgiHowtYsfls4hykKoKDHiB59/04o33Vajsi2WNP11eie/VfDTsY6+cuoDZ480oHaUeyIPzyvDkb94J+9i5Wwo+OXdmzO0yVN4HofoCo9AkSYY3m5bOikDtdqPbeQjGGXNhnDYHgGCtEYpZZWUlHA5HTJ1Zl8sFq9UKp9MJIHIQYbFYwh430v6RtseipKQEiqJAUZSoOvjRnlObKg34O9culyvw2rQ1daOR6GuW7PZGMpb3jcZsNqO6uhp2uz0QxAwdtaa1XVGUsMFkpOUDopGs4xJR/vKpArIEHPtQxW/bVVzKw9ntpiIL1qz7//DSM3+DL/3FzwLbjx9pwfjJFfjDP/zDwDa3243W31zAiwf7cLxm8HNfCPzln3wZm//hSVy9eRvHTp/De8/5/5btadmPcxev4HMPVeOdE6dw78J5kIwmQJLwyCOP4LHHHsMffP5L+P0HfSl9zcP97MdP4A3HS/jB7l8Fbfvbb/4x/u6Jf4/qGLue+C7uW/EwvvW3Pwxsu+Q6i29t+Ax+sPvXKDFbEt3sIBdvenFT8dcasRTrIITgsr0UNcYWjC3iwdgidrzzQ5RDfKqAEAJHTqr4wX968PpJJkSyzdKZk/Hupesh2zt6+/FfzjP425qPjHqMLy6ei9u9fWFnnPxX+xmsW14ZW6OMJhjmVAYSIgCgegbg67od23EylVAxcPED9BxzcNYIxWXt2rUAEHGq8XCtra2BETzh1lGNRqSAYizTpeMVyzlbW1uxfv167Nq1C4B/jdponz/Wa6YV6ovFWNo7mrG8b4ay2WxwOp2BAOj8+fNBbdSu1/ARXmOVrOMSUf5RVQGfT+CN91X8c4sH9ld9eZkQ0SxaXodlD27AS09/B2+9shuH9zfBff0M/tvWA/inf/onfPnLX8Z9992HM2fO4OLVa7jR3Ys/+h9/h5//539CCBUVZdOx8zub8MGHLvT09mHzPzyJP/kff493TpzC+ZeewX/80za88vrbaPjhv+Ivtnwbjz76KL797W9j165d6POk97q/f+xt7HpiW1AyAwC+8rVv4s3XXsYrzz8b1TEA4P4VDwdtn2GtwJbv/QhN3/t64ho8gj6PwLvn+nHyYj9UAc4aoagxtmBsEQ/GFrHjTBGiHKAKAVmScOGGwC9f8+HKLXa4stXnF8/FXz33KtY9UBm0xNUX9vwSf3r/Inx+8dyg/df97Hm8d+kG3vrWfwtsKy0swP/6wifxvbbXsPcrnw5s/0X7acyaUBJyjNEY5i2GpLvz50IIFd7bWbx0VgRqbye6jzlQYF0I42QrR3RR1KxWK7Zs2YKmpqaQ0TbhHD16NDA9e/HixQAiT5l2u91RF8tLlM7OTpjN5oQHQXa7HU1NTWhpaYnrNbW3t8Nqtabsmo21vaMZy/tmKG3bvn37sHbtWixZsiTkPEBipuWn4rhElB+0QSgDHuDwcRWHj/vQnd4JChmlouoRVFQ9ErL9r//6rwP/F6oKz8m30d2yG0Wf/SqMiz+C3tNvBx5/8+e7Ix7/L//kywCA4nsfhqw3AvDHlOlOivzH7h9gfuW9mGGtCHnsoZo6/PLpf8WDn/7iiMd487WXsWDxfWEfm1+5FB8ceycRTY3aFbcPHT19qCovQJERjC9oVIwtosPYIhhji9hxpghRllNVge4+wP6qF837vUyI5IB//sIn8erpC/he22v+BMnPnsdffmIp/vkLnwy7f2mhMWTb5xfPxbrllf7EyJFjePK3b+PD2wqeXf+5mNtjXLQMQr2zuHCuLJ0VlupD/4dO9J5+B1B9LMJOUauvr0dVVRU2b9484n5OpzOoY2k2m1FTUxO2WCHgLypXX1+f0LZqIo2KOnDgAB577LGEn6+pqQmrV68O6aAPHaHU3Nwc+P/w0VeKoqC0tDRl1yzW9sYj3vfNcDabDU8//TRaW1vDBjc1NTURR40NXTM4Vsk6LhHlLm20fFcvcOCID//zaQ8Ovs2EyJjJOkACEEvfVZICCRFNf5qTIm++9jKml4UmRAB/QuPN116O6ji/fPpfw26/5DqL6WWz421e3HoHBN463YerHf6YijPTaTSMLUbH2CIUY4vYMClClKXUwaWyXjuh4p//04OjZ3nzNpds+vhSfK/mo/jnL3wSe7/y6YizO/Z+5dN4+f/9w7CPPTivDN+r+SjWLa/Epo8vxaaPL429IYYCGOYtCVo6S3gH4OvMkaWzIvDevoJu5yGoPQqDlhgUFcgYZ5Ky4quoIPFdoJaWFqxYsQKrVq1Ca2tryOOtra1wOBwhHcsdO3ZAUZSQjl5DQwOqq6uD1nAF/KOVwk11Hml7OGVlZSGdzsbGRixevDhsxz/Wcw7fXlpaGjLyp7W1FdXV1ejs7Aw5xsqVK9He3h743uVyBUaYxXrNAIQ9x1BjbW+4Y0Qj3vfNUDabDYqiRPxZ79ixA4D/5zuU0+kMux5ypNcxfHusxyWi/KUOrul7UxH4+W+9aHzGA8cxFQPeNDcsR/hndUsxJUUkgyn4e6Q/KdI1QiH0ktLxAO4sjxXJJz/1Rbz52sv422/+cUhh9Z/9+Al85c++OdZmxkUVwMmLAzh5qR8CXE4rGowtGFuMtJ2xRXiMLaInCd7tIco6qhC43Qn8/LdeuK7zVzhd/uhhPRaVR9/56fiX70G9mV0zLAwLl2Hcl+50YISqwnPjAvrPH0tjq1JIkmCcMW+wCHt+Tnfv6+vD2bNnUVFRAZPJFHG/bFxuLFltdjqd2LVrFzo7O1FSUhIYDbRmzRpUVVVFfJ7W+dOK+VVVVQV1wF0uFxobG3H48GEoioKamhqsXbsWVqs1qu1ah762thaNjY3YunUrHA4HDh06FNM5N27cCLPZHPM5FUXBd7/7XXR2dqK6uhrAnenZDQ0NqKysDBx76DU5duwYqqurUVVVFXhetNdM+1m0tbUB8I8+WrJkSSAwi/T6qqqqom5vR0dH2GsxvK2jifd9o1m1ahV27tw56nuss7MTVqsVZrMZVqs10M5Y3l/aNYrmuNGI9nOGiLKP9rf26m0Vz7/pw8kLjF3GYse6OzM7hi6fVfyHG2GYfw96TrwGtTu69fF148ajaGFwvcKjH/bhVlf6Btt9tnom7vvoQ2ELqr/y/LP43jf/GN974t9HXULrZz9+Arue2IZxZgu+94N/w/0rHsYvn/kxSkrHj/rcVBhnklBlLUCBQcq6/vNYMbaIHWMLxhaMLZITWzApQpRFfKqAJAG/Pari5Xd98PpGfw4lTz4kRYq/uAGGBfdC0t2ZKdJz8gh8nTfT2KrU05VMgGnOPZD0BkhSfk2y5M1KouygBaPZiJ8zRLlJVQX6PMDzb/jw5ikVvPMwdpGSIuNsfwHDvMX+mc69I49e1ugnTEfhnHuCtr1xqhfd/en7QX1rw2cBAD/Y/auQx7RERzRJEeBOEgUAZpRVoKn5l2FrlaSLTgYWzjRikjm/Sv3ybz5RdsiH2CK/Pn2JspgQAjc6BH7+Wx8us24IpYLeAMNdS4ISIsLrga/rVsJOcfbCZfztj34MABhvLkFpSTG2f+PPUn6M0fg6b6HnmAOF85ZCLirNulFLRJTbFEVBeXl5uptBRATAP5ALABxOFa+850O/J80Nygf6wVs7MWSeZGMhhFCDBvyku9D6V/7sm9hSH74G4on2twAAnR3RLeM7rqQUX/naX+H9Y+/gzddexpb6z+F7T/wb5lfGsaRwEvhUwOkaQNlEFXOmGgDk56x0Iso8+RJbMClClOFUVUAAeOkdH357VIXKfAiliGFuJSTDsNFot6/EFGyN5LkXf4sn9j6Nn3z/O6gomw4AcHd2oeGH/xp1UiMRx4iW8PSj58TvUVBeBePksoQem4goFk6nE/v37w+M3jpw4ABWr16d5lYRUb5TVQFZlvD+BYEDR7y4Fd2EBUoE2X9rR8RSU8RoAgT8xUTgT2b50lym8v4VD+NzX/4adj3xXWz85o7A9leefxb3r3gYrz7/bKC2yEh2PfFdLFh8X+AYv3zmx/jB330Djz36MTQ1/xL3r3g4aa8hVhduetHZq6LSWgC9TkBmYoSIUixfY4v8WgOEKMuoqsDtLuBffuXFq+8xIUKpZVx0H4TvzhptkizDezsxy3+9c+IUNv39k/iv//P9QDIDADb9/U489+LvUnaMmAmB/g/b0ffhMQghWISdiNJi//79gbWMFUVBaWlp0HrJRESppPWHbigCP27z4D9eYkIk1aS4ZoqYgCE34AfSPEtE862//SFmWOfgl8/8OPA1f9G9gWTIuJKRi+3+8hn/DPKhS2x97stfw/890I4ZZRX43re+GlKAPd06elS8cboXSo/K+IKIUi5fYwvOFCHKQKrwjxB565SKX7/ug8eb7hZR3tHpYZh/T/DSWT5vwmqJ/O0Pf4xvrnsUlpJxQdsfemApllXOT9kx4uW5fh5qXxcK5y6F0Onyrs4IEaXXxo0bAQDNzc0AECjuSESUaqoq0O8Bnn/Lizff5yCutJEH++yxzBQpKAos1ySEQG+GJEUAfxJjuDdfexkAsKBq2YjP/dm/PoH/29oesn2GtQK7nv4dvlJbhTdfezkjCq4P5fEC757rx7zpBsycYEh3c4goj+RrbMGkCFGG8akCXh/w7CEv2s+lef4y5S3DnGFLZwnVP0skASOX3jlxCi+//jZ+8o/fCXlsfd2alB1jrHydt9B9zIHCu5ZBNo3jGsBElDJmszlrCx8SUW7wqQISAMcxf92QvoF0tyi/3ZkpEn38KBvvFJ8VAPozKCkSzvvH3sb8yntRYrZE3KdTcWOcOfJMkhKzBX+04Vu4fOFsElqYGKcue9A3IDB3mhFCCMYYRJR0+RpbMClClEGEELh0U8D+qhfurnS3hvKZYeEyCJ8vMFNEkmR/PZEE2NOyH7NnTguZ4ZHqYySCGOhFz/HXYKpYAr1lKoMWIiIiymnajPZTFwX2H/HippLuFhGAwEyRqJdeknWQdMG3g/o9mT0g7+W2Fmz8q8dH3KfEbEGX0jHqsaaXVSSqWUlx4aYX/R6BhWVGgIkRIqKkYFKEKAOoqoAkAa+8q+Lld32cdk7ppdPDuHD40lk++JQbCTn8y6+/jYqZ/hog/+unzwAASscV4+zFy/jmOltUiY5EHCNhVB/6Tr+DgrIFME7L7ACLiIiIKF4+VaB/AGg55MEJFwOWjKKLbabI0FkiACBLUkbMFHnl+WfR9L2v41eOiyHbzebxYZfVGm562Wy8cfiliMXU33C8hO898e8JaW8yXVd8GDjXj8XlBdDJTIwQESUakyJEaeZTBTxeYN8rXpy6lP6OKJF+9gJIQ6fTqyq87sQsnQUA5y5ewb0L5+F//fQZ/OWffDmw/eyFy/jEV7+B3/zbD0dNaiTiGInWf+Ek1IE+FFgXAgADFyIiIsoJ2hI+718QeM7hRXdfultEw0laTZEoR9dJw5IiQGYsn9XZcRsLKpcGbXv/2Nt46oltaGr+Zcj+f/vNP8YHx94JqiHyvSf+Hd/a8BkACEqMdCpuPPXP2/CVP/vmiEtwZRKlV0VXn4rSItYvJCJKNCZFiNJIVQVuKgL/dtCL21wuizKEcdGwpbNkGd4ELZ2leefEKfzd14NHelWUTcdDDyzFpr/fiZ/+49+k5BiJ5rn2IXQlE2AYPzXl5yYiIiJKNJ8q4FOBX73mxVunMnt5pbwWmOEdZVLEYAqpV9GXAUmRz335a+jqdGPXE99FV2cHlI7bmFE2G7ue/l3ERMbwGiIlZgueevoQdj3xXbz6/LNBjz32V49nTUIEABbMMKK0SOZgKyKiJGBShCiNjp1X8Z+/88HjTXdLiAbJMowLlwYvnaX64O1IzNJZQ1WUTQ/Zdu/Cedj8/R/C3dkV1UyPRBwjkQxTZjEhQkRERDlBCIGLNwSe+Q0HcGU8WYZQYyyyLgQw5GZ7JswUAYCvfO2bUe/7dyMsg7XxmzsS0Zy0qZhqwJRSHRMiRERJwjl4RCmmCgEhBNre8GLfK0yIUGbRz1oAqaAw8L0QKrzua1GvTxwtrR7IcLMHt7997IOUHCOR9OOnwVS+KKXnJCIiIko0/+wQgeff9KH5ABMi2SCwfFa0+w9bPsvrE6xrmUFmTtCjfJKBCREioiTiTBGiFPKpAl4v8DPWD6EMZVy0NHjpLCnxS2fNnjkNpSXFI+5z7uJlAEsjPp6IYySSrmQiTHPuDlmGgIiIiCibqELgliJg/40PV24xXskasg7RLp0FAHJBYUbOEiFgslmHudMM6W4GEVHOY1KEKEV8qoC7C/jJCx7c6kx3a4jCkGQYFt6X9KWz7l04D+cujpxoWVo5P+nHSBS5sASF85YBkJgQISIioqykqgKyLMHhVHHwbR+8vnS3iGIiyzHN7JaNRYF+qxAiI+qJEGApkrGwzJjuZhAR5QUun0WUAqrqX4/3X37NhAhlLn35XZALiwLfC6HC23EdUBMbFdd96hN458SpsI/5Z3f4Z4Ik+xiJIBkLUTh/OSAzIUJERETZSVUFuvqAH7d60PoGEyJZR5IgyTKEiD6xIRkLAv8XAPo8iV0ql2JXXCBh8awCSADjCiKiFGBShCjJhBA44RL4cZsXvf3pbg1RZIbBpbM0kiTDeyuxS2cBwBce+TgsJePw3Iu/DXnsuRd/h/VfXD1qgfREHGOsJL0RRQuWQ9LrIUn8cxpLIJ4psrHNREREiaL9HTx6VsWTz3lw5gr/LmalQD2RKH9+On1IDRIun5VeBQYJd882QZKYENFkYz89G9tMlM+4fBZRkh0+ruLAER/495EymiTBuGj40lmDM0WS4Cff/w42f/9JPPjA0kDyYk/Lfpy9eBk/+cfvBO37J//j7/HOiVN477k9cR8j4WQdCuffD8loYkJkkCRJ6D3zLtS+7nQ3JSqyqRiFc+5JyrGdTifsdjva29tRVlYGALBYLKivr4fVaoXD4YCiKKitrU3K+RPN5XJh8+bNcLlcuRQN6gABAABJREFUsFqtaGlpSXeTAtJ9rUe6NoqioK6uDjabDfX19Uk5PxFRvFRVQAD4pcOLNz7gLIGsphu8rRNlpXR5WJF1WZKYFEkjvQ64Z1YB9Dr/z4L8GFvcke7+bqIxtoiMsUVqMSlClARaseX9r3vhOMYggzKfvmwu5KI7MyuEUOFVEr90luahjyzFzm9vwqa/34nx5hLcVjoxe+a0kMSHJtysj1iPkTCShMJ5SyEXlnAk1zBqXzfUHiXdzUirxsZGtLW1YcuWLdi+fXvQY83NzbBardi2bRu2bNmSphbGTuuQr1+/Hh0dHeluTkAmXOuRrk1HRwdcLheOHj2atPMTEcXDpwr0DQD/8ZIX56/xZni20wY1iShrikjGwpBtTIqkhywBS8oLUGCUmBAJg7FFZvR3E42xRWSMLVKLSRGiBNNGXT3zqhft55gQoexgWLQMwucLBFXJWjprqIc+shQPfWTpqPv99B//ZszHSCTT7CXQlUxkQoRC1NXVAQAOHjwY9vH6+no0NjZCUbIzuLNarRkTuGTatQ53baxWK06ePJmS8xMRRUsVAldvC/z7i14oPeluDSWENtM7yqUJZKMpMIhPw6RIelRajSgplBlXUFiZ1t9NNMYWkTG2SA0mRYgSSFUFfCrw04NenOWavJQ1JBgrhy2dJZK3dFY2KyhbAP2E6QxcKERzczOcTmfEjrRm69ataGtrS1GrchOvNRFR/N47o+I5B4up55QYa4pIRpM/gTI0KeJl7Jpq82cYMWGcjnEFhcX+burwWucvJkWIEkRVBTw+YO/zXrius1NJ2UM3swJysTnwvRACvo6bgM+bxlZlHsPU2TBOq4jruaoQnBKfw1wuF5qamlBdXQ2r1Trq/jU1NSloVW7itSYiip0qBCQAB474uLRvDpK0miJRLp8lG0zAkG6pxytY/zLFZk02YPp43o6j8NjfTR1e6/zGT2GiBPCpAgMe4MdtXly+xR4lZRfjoqVBS2cBgOd2cpfOyjb6CdNhsi6M+/m9/QJFBeBIsBy1b98+AEB1dXVU+69ZswYulytke3Nzc+D/brcb5eXlsNlsgW1OpxPbtm2Dy+XCihUrsGPHDtjtdpjNZhw6dAgWiwXbt2+Hoiiw2+0AgKNHj8JqtWLr1q2B4zgcDjQ1NQWOs3btWhw6dAgAAkX9hu4/GkVR0NTUBKvVCrfbDZfLhY0bN6Kqqirwug4cOACn0wkA2LBhQ+D4q1atCpyzuro6ZP3e4cZyre12O+x2O5xOJ8xmMx599NFAO1pbW7F58+bAsffsuVObSHtOSUkJAGDlypWjnt/lcqGhoQHt7e0RC0jGc1wiolipqoBXBfa97MX7Fxmn5KTBmSJCjbKmSEEhJEkOfN/nYaIslaaP12P2FEO6m0EZjLEFY4vhGFskB5MiRGPkUwX6PcDuA15cczPQoOxjrFwelBABAK/7Wppak3l05okwVdwdsvZyNIQQuHzbiw8uezBvmgEzJzIAykXHjh0DgKhGFwFAVVVVoFOvqaurw2OPPYba2trAtsbGRmzatAlPPvlk4Hla4b3Ozk7Y7XbU19cDAGw2G5YvX46SkhJYLJbAdgBYvnx50Lbq6mq0tLSgrq4Ohw8fxsqVK4MClU2bNqGuri5sZ3s4l8uFuro67N27N/Cahm+rr69HfX09GhoaYLfbsXHjxsDzbTYbXC7XqAGLZizX2mazwWazYdWqVSHBWW1tLTZs2BASLG7atCkQEGoaGxsBjBw8Wa1W7NmzJ2IByXiPS0QUC58q0NMP/OR5L67cZpySqwL9+GhnigwptC6EQB/riaTMxBId7prOeIBGxtiCscVwjC2SQx59FyKKxKcK9A0Azfs9TIhQVtLNmAW5pDTwvRAqfMpNwOdJY6syh1xkRuHcZQBin+UhhMDNTh8+uOy/lqeueHDuGq9rLtI6pmazeZQ9w2toaEBpaWlQ0AL41609fPgwWltbg7aXlJTA4XCE7L948WLs3r077PYDBw6EnLe0tBRWqzWoow4AO3bsgNPpDHSkR2v7ihUrggIxq9WKFStWoKmpKWjf7du3o6qqKjBqSlEUuN3uqIMWYOzXGvAHMA6HI+JjGrvdjra2NmzZsiVon7a2tsCostGEC7AScVwiotGoqsB1t8D/+aWHCZEsI0tAaRFQNknConIJyxfIWFEp42NVw27fSBJ0k2eg4P4H/d/qjTBMnQ3DlFkwTJoJXekkyIUlkPTG4KcZCgL/F2CR9VQxF8qoLDOOviPlPcYWjC0iYWyRWJwpQhQnLSGy+4AH10MTtZSjCo1ASZGEkkKgtDi25xZ/fj1Efx+g+iB8XsDrgdqlQHR1QO3qgNrp/1d0dUD0difnBQxjXLhs2NJZErxcOgsAIBUUoWj+/YAsxZwQUYVAZ6+K4xcGgrZ/eN0Dr09g3nRjXDNPKDOVlvoTi4qixPV8u90esfOuBQBDgxGLxQKz2RzSKbZarRG3h5tSP7TtQ5nNZtTU1ODpp58ecaq7oihwOBwhHXDAP117eOACADt37sSqVatgt9tx/vz5mKbSD21vvNca8AcnTU1NsNvtgUBFURRYLJag/ZqamlBTUxMSJFVWVmLNmjVxnz9ZxyUi0ggh8P5Fgadf9WKAJeIyilEPTLFIMBdpMYWEkiLAXCShtBgoKZRQWBDcPxTCX/MjXOpCnjAVxvFT/P8vKEJB2XwAoX1XIQSEdwDCMwBJvpNckQDoZKC4QEJPv4iyVDvFqqhAwpJZBZCkyAOtfKqAPMLjlD8YWzC2iAVji/gxKUIUBzWwZBYTIrmmpBCYMVHC1PFSIFCxFPuDlmIToNfF30nVT58V9L1Q1cFp7lLI8lXC54Po6YTa6Yaq3B5Mnrjhu34Z3svnITpvx92OoYyV94dZOutqQo6dzSS9EUXzlwM6fdCay9FQhUDfgED7h/1Qw0SWF2954fEJLJzJxEiuqKyshMPhiBgchKOtdauthRsugAD8QUq440baP9L2WFmtVrS1tUFRlIgjp9rb2wH4X4u2zvBQ4QIaq9WK7du3o6GhATt37oy5XWO51hqz2Yzq6uqgwOXAgQNBI7kURYGiKGFHY2lLDsQjWcclIhrq8HEVB474WDw7zYx6YPoECTMnSZgxUYJ1sowJJXduegshoPpDgRFvhkuShHAPSf477MHfY4RjGAqAIbNEtO3TxxswfbwBqhDo7lPR2ev/6upT0d3HRMlYGfUS7p5VAFmO/DNWVYEbHQITzRJkSUCWGR/kM8YWjC2ixdhibJgUIYqRqgp4fMCeNi8TIllOS4DMnCRj5kQJZZMlFJv8HVCf6h+OJcmAnKSb1v5RWuFvuEs6HaQSC+QSC8S08pDkidrbDd+lc/BePg/f5Q/jSpToplkhl04IfC+EgK/zFoQ3z5d4knUonH8/JGNBXAkRj1fg3XP98I6wrPO1Dh+AASZGcsTatWuxe/duOByOoPV2I2ltbQ10XMOtCRuNSMHEWKZ+x0oLkqqrq0Om1Y9k8eLFsFqtIaPUojGWaz2UzWbD5s2bA0HN+fPng66d9nMZPsJrrJJ1XCIizcvv+vDi2750NyPvjJQAUQdneuiG3eiWJAnDxiallSxJKCnUobhAxvTxd9rOREn8dDJw96wCGPRSxJjSpwrc7vTXKJ06XsJXV+lhABMj+YyxBWOLaDG2GBvWFCGKgSoEVAH820EvLt9iVzCblBQCC8okPHyvDl99RI9vrzXgv9uM+OoqAz55t4y7yu4kRAB/0KLTRe68ppIky5B0+qAZHXJhMfQVi2Ba8WmM+/Kfw7LpH1D6zSaMW/t1mD75BzAsuAdSyfgRj2sYXDprqLxfOkuSUDhvmX/95RgTItpov/c+7MeAd/TPh2sdPnxweYAJkRxgtVqxZcuWqEcZHT16NLBO7uLFiwEg4vPcbnfUhf8S6dixYzCbzSMGQkOLH8Zi//79aGlpQUdHBxoaGmJ67liu9VBawLRv3z64XC4sWbIk5DxA7K9tNMk6LhERALz0DhMiqSJLQMU0CauX6/CXdQZs+yMD6tcYULtchyUVMiaa7yxhJUtSSEIkk8lycNtLCnWYZtFj/gwj7ptbiI9VFmJpRQHKJ+lRXJA9ryvVJAlYUl6AooKREyI9/cCe5z3oHQDOXRVoPuBF38DgID3KS4wtGFtEi7HF2DApQhQlMbiQ6/992YtzV9lByXSyBMyeKqHmfh2++aXREyCZkPyIlT9ZEiFR8oeDiZKv/z0KP/Vl6GcvAOTgj3xjVZils27n99JZpoq7oSuZEFdRdSGAox/2o6c/+s+Hy7d9OH1lYPQdKePV19cHFfqLxOl0BnWStTV2wxUrBPwF8qIZtRSvcKPJtPV8H3vssVGfv2HDhrDT2wGEDUoaGxuxceNGmM1m7N27F3a7PWJhwkjivdbD2Ww2PP3002htbQ07qqympiZi2yK95mgk67hElN9efNuLl95hQiSZTEZgSYWML39ch7/5bwb8Wa0BH10kY1IWJ0CiFZookTF7igH3zyvER+ebMHeaAZZiOewyX/lqUZkR5iJ5xCWzvD5gb5sXHUPKSV65JbDr1x509TIxks8YW4RibBEeY4v4MSlCFIOf/9aH9y+wY5KpjHqgapaEL31Mh+98xYANqw2orpQxoST7EyDRCkmUlE5AwX2fRMkf/SUs3/oBir/wNRgq74eubA50lkmB/YQQ8HXdhvDm7w36grKF0I+fFldCBACOXRiA0jvCmlkRXLjpxblruXHdZVMx5CJzdnyZihP++ltaWrBixQqsWrUKra2tIY+3trbC4XCEdJJ37NgBRVFCOq0NDQ2orq4OWo8W8I/wClcMcKTtkbhcrpBO9He/+11UV1eHDZiGH3/r1q0wm81obm4O2h4uGGhsbARwZxp+VVVV0FTzWMR7rYey2WxQFCXi9dmxY0dQuzVOpzPs+sqRCjQO3x7rcYmIRnPwLS9efjf2PgiNbvw44KOLZHytRo/vrDXA9kk9FlfIKDD4+4u5mACJhr/Oif+1FxhkzJigxz2zTVi5sBCLyoyYUqqDPoOWBku1edMMmFSii5wQEf4lyP7toBdX3aH3F252Av/yaw9uKSKvEyOMLRhbaBhbRN7O2CJ+khAsv0YUjf867MXrJxlsZJrSYmChVcaichkV0/wjs3yqyNsAZTTC54Ok00FoNUqGFHrsP38cnuvn09vANDFMnQ2TdWHczz95sR9X3GMbnTlnqgHWSYYxHSMZ+vr6cPbsWVRUVMBkMkXcLxtroySrzU6nE7t27UJnZydKSkoC05rXrFkTdrq1RuvIagUQtY69xuVyobGxEYcPH4aiKKipqcHatWthtVqj2q4FQVpnfv369QD8o6MURYHL5YrpvNXV1WHbDvjXAtZea2NjI55++ulAYcUjR44EjltXVxfYvmLFCuzYsSOmtYvjvdaaVatWYefOnaP+XDo7O2G1WmE2m2G1WgOvPZafycaNG4POM9Jx8020nzNEFOqFt7x49T3GKIk0fYKEqlkyKmdJmGKRAzOCWeMhOqoQkCUJQgh09Ki42enDdcWHfk9+3HqyTtJjzlTjiPsIIbDvFS+cH458TQqNwIbVekwqzZ0ZSIwtYsfYgrEFY4vYRPs5w6QIURQOvuXFKww2MsaEEuDeuTpUzpIwbTwDlXgN77QNXP0QnuvnofZ1j/Cs3KOfMAOFc+6O+/lnrw3g/HVvQtpy13QDpo/XZ1QAwJuVuUsLXPbs2ZPmlqRPY2Mjtm7dmu5m5D1+zhDF5/k3vfjNUcYoiWDQ+ZfGWrFIxvSJMnyqgCwho/pk2Wjo7aZbXT5cvOXF7a7cfc9OLdVhYVnBqPv98jUvfn8iuutQbAL+/DMGmItzY2YS/+bnLsYWjC0yRbSfM/oUtoko6wgh8OYHKhMiGUCS/IXSP7pQh3kzZaiqCKxZ65++nd72ZaOhQZ4QAoYpVhinzoK38xY81z6E130NyPG8uc48CaaKJXGN6hFC4NJtb8ISIgDwwWUPZFnC1NLI0+2JKDEURUF5eXm6m0FEFJfWN7z4XTtjlLGaaAYeWKDD/fNlGPV3ur65cPM5Ewztz44fp8PEEj36BlRcvOXFFbcX3hwqgzN+nIwFM42jxhWvvueLOiECAN19wL+2erDxMwYUmbgiAlGmYmyRfZgUIYpAVQXOXxP45Ws51FPLQsUm4P67ZHxkoQ7mYimwpipnhSSWv+M+uDbyOAv0JROgevrhue6C57oLwtOf3gYmgVxkRuG8pQBiHwUohMCNTh9OXfYkvF0nLw5AJxtHXIeYiGLndDqxf//+wOitAwcOYPXq1WluFRFR7A4c8eKQkwmReMkSsMDqH2w1d4YctPQuu17JIwdqkEiYM9WAiqkGXHP7cOm2F51x1OXLJCUmGVVW/wyRSP13IQTePq3ihbdiv7/g7gb+tc2Dx9YYYDIIxsJEGYCxRfZjoXWiMHyqQEc38B8veeHL7v5Z1po1RcKjn9Dhrx814JFlOpQU+bdzZEzySZL/T4NsKIBx+lwU3/0gTHPvha5kQppbljhSQRGK5i8HhhSJjJYQAkqPiuMXklcc/fiFAdzuVsEVLimZOjo60NHRke5mpMz+/fvR1tYGwD+Sq7S0NKY1homIMsH+15kQide4QuDBu2Vs/bIBf/SwARXT8rtYerpoRdplScIUiw7L5piwbE4Bplp0yMYfhckoYcmsghGXW1NVgVOXBJ47FP+AyxsdwJ42Lzw+//GIMg1jC8YW2YYzRYiGUVUBrxf4yQse9CbvnieFYdQD98z1r+U7xSKzYHoG0Dr2+tIpMIyfBrWvGwPXzsNz8yLgS9yyUakk6Y3+hIhOF0gARUsVAr39AkfP9yd1ZTEhAOf5ftw9qwDmIpkzRiihtAKCTqcTALBp06aQ4oa5aOPGjQCA5uZmAP4ikERE2eTXv/fi8HEmRGI1xSLhwXtkVM2SIeHObBCOtk8/bfbIOJOMBTOMmDcNuHzbi/M3PFmxtJZBB9wzqwA6XeSEiE8VuHpb4GcvezHWXMblWwI/fcGL9TX+td5kxgiUARhbMLbIViy0TjSEVrB77wtenLnMX41UKSoAPrFEhwcWyDDoAQGwg5ehAn8yhArPjQsYuHwmu5bWknUoWvhRyIXFcSVEPF6Bt870Y8Cbms8HvQwsm2tCgUFK2+8EiyESUbLxc4ZodEyIxM5SDDx8rw5L58lQBWeEZAshBFQBuG544LrphZqhb3udDNxbYUJRQeR+uk8VULqBf/m1B919iTv3XTMl/PEj+hFnp2Qq/s0nomRjoXWiOEiShF8cZkIkVYx6YGWVjI8v1kGvuzNaK7u6dfkl0OmWdDBMtsIwqQwDVz/EwJUzmT9zRJJQOG8Z5MJxcS2ZparAe+dSlxABAK8KtJ/vx7I5JgjEXgyeiIiIspsQAoecKhMiMSgqAD55tw4fXeQfACNJEnTsQmUN7ec1a7IBMycYcO66B5dve5M6SztWkgRUWQtQXBB5KV5VFegfAH7cltiECAB8cFHg6Ve9WPugftTC7kREFB6TIkSDhBA4fFzFG+8z4Eg2nQwsny/j4aU6mIycFZKtJEkGJMA4rQLGKVb0XzoNz7XzgMjM3yFTxd3QlUyIKyEiBHD0w370DKQ+GuvpFzjuGkBVuTHl5yYiIqL0UVWB9y8KtL2ZBesIZQCjHqiulPGJJcEDrig7SZIEvU5g3jQDrBP1OHvNg2sdmfG7sGCGEZbiyEvcqkLAq/pXoLjdlZw2OD8UePaQD3Uf4209IqJ48NOTCP5prZduCrQeyYxOVq6SANw9R8anlulQWjy4jQmRrCdJEoSsR0HZAhinVWDg4gfw3LgI/0JomaHAuhD68dPiSogAgNPVD6U3fcmem10+nLvmQcVUJkaIiIjygU8VuN7hHw2eSSPkM5FOBu6fL+Phe3UoLOCAq1yi9d0LDMCisgKUT1Jx5uoAbnWlr19eMdWAKaW6iHGFEAIQwH/8/+z9eZgc9ZXn/36+EZm1V1ZpX0sbIISKTSDZRngFbAnadjdy28JuzwzYYGbsn+H+umGee3sa9Qztmef5WWrPhbnuHpY27hlPN2W31YttLTZgbDcSZpMBlRYQ2lL7WpUl1ZoR3/tHKguVVFWqJbMiI+L9eh4MrkplfitVGREnzvec83xWh04W98P7xi5fFWVZ3fEBbu0BwHBx5ETs+b5Vd48KMvgMA5s/w2jZYldTxjnyKfGNnN6/z0SZKuZcrbKpc9V14B1lW44GuzCdq2SZMmdEf9YYo50HuwINvPL2n8iqpsLRxNTAQRgAAAg/37fq6JL+1y+y6i7x7qRBMpKumevoUzey4Srq8n+vVeVG18yuUOtZT7uP9oz5pqUZ4xOaNTE56GOMMfqH32T13hi15N60zVdFmadbrnfH5PUAICpIiiD2jJGafpVVpj3olURTwySj5YtdzZ7iyD+XdWL3VnTlAxZTXqXKyxfJO9uqrgM75bWdCmQ9iQnTVT7zyhH/+T1Hu3WkpXQqyHYc7Nai8gpVsQsSAIBI8s8Nmf5fzxGfDGbqOKPPfdjVtAlsuIqT/N9zbZWjRfMqdKw1q12Hu9UzBpfrk1KuLps6eEJEkja8mtWbu8c2WfPC7zxVlUsfXDBwSy8AQF8kRRBr1lr98k1fuw5RIlJoVeXSZz7k6pq5rrx8MoS+vrGRvxh3qmpVdeUHlG05ps59zbI9XWO2BrduoirmXDOi4YPWWh06ldX+E6W1PdO3ucHrN15WIeNwAwAAgKhxjNGzv+opetudsHKM9LFrHX3iOre3USsbReIn/3c+MeVqXE2l3jnUrROZ4mVG6qscLZg5eBtba602bfP1r83BVJive8XTtAlGMydKLnE3AFySE/QCgKB4vtXuI1a/fLN0doFHReNso/97RVILZ+cOMVyUxZcx534H6iaq+uqPKDFh+pi8rlNdp8rLFp1bw/ATIifaPO060lOMpY1aV49V8/6xSy4BAICxs/G1rLbtJyHSn6njjL7+2YRuud6V4xhiDMgxRglHamwo11Uzy5QsQgep6nKjq2eXy2jguMK3Vlv3+oHOKPVtriV4R5d6OzQAAAZGUgSxlO/Ty+DCwqoql+76uKsvfiKp8jKSIXifMY7kuKqce60qL79BJllevNcqr1bVFYslM/zycWutMu2+th/oLtLqCqO13de7h0szaQMAAIbPt1avv+vpN1uDn2NWahwjfeI6R1//TEKT6gyVsujDnFc1suSKSk1MFS4zUp40unZOhYwZJCHiW+07avUPv/EU9K2FMx3S/3khG/g6ACAMSIoglozJ7aI42xn0SqIjXx1y1azcYYUydlwoH0gUs2rEJMtVdeUSyR3+MHLfWrV3Wb29vysUydLDp7M6dKpHNgyLjbGmpiY99dRTQS8DAFDC8jdV/2UzFewXojoEQ1XoqpGEK103u1wJd+DY1vOtjrda/eD5rLwSyWemj1v97LccS6KK2AIoHJIiiB1rrX79tq99x7iRWAhUh2C4ilY14iZUOX+xTLKst23XUPnWqidr9da+rpIJaIZi15EetXX48ksgMWL9EL1x54zFmjds2KAnn3yy6K8zUul0WitWrNCSJUu0YsWKPt/LZDK67bbbCLwAoIg836rljPR3L5TOTdVSQHUIRqJQVSOOka6ZVa7yMjNoQuRMh/T9n2fVVWIF3K/s9LVllxfqNlrEFv0jtgAKh0HriBXPtzrRavXC79g5UQiNs43+YGlCZcnc/6c6BEN1YdVI5/5typ48NIondFR5+Q1yKmpG1DLL96U393apOxuuwMFaafuBbi2+vEJWwQ5eN46js//0PXknjwS2huFwJ0xV9R98paivkclktGnTJklSc3OzGhsbi/p6I9HQ0KC1a9fqnnvuUWtra5/vtba2Kp1O6+233w5odQAQbb5v1ZOV/vYXPeoo7c6dY2rqOKM//KirKfUkQzAyjjEyjlVjQ7mOtWa163C3eoZxC2BhQ5lqKwduxZv/7D6zsUdtHQVadIH98+bc4PVJdeHcuEhscTFiC6CwSIogdn74K49dWKNUVS599iZXV89x5VtLMgQjZowj6xhVzr1W2XFT1bmvWbZn+EPEK+ZdK7dm3MgSIlZ6a1+XOrrDlRDJ6+yxevdwtxbMKN6clqHyTh6RdyQd9DJKxvr16/XQQw9pzZo1ampq0qOPPhr0kgbU0NBwUeDS0NCgnTt3BrQiAIg+Y3IVIifbgl5J6Vh8haPP3JTb3U9CBKNxftVIfXWlmvd3KdNx6RsB86eXaXzNwK148/HD3/4iqxOZgi65oLKe9H+ez+obn03KJMMZsxNb9EVsARQW7bMQG9Za/eJ1T0dbwnnjs1TMmmz04J3MDkHh9K0a+bDc1IRh/fnyWVcpUT9lRAkRSdqW7lLbEAKkUna0xdOJTJb5IiXmpZde0n333adUKqX169cHvRwAQAnJt/TdfYRzt5RrV/R7H3T1Bzcn5Jhw7mxHaXKMUdKVrptbril1g7fTmj0pqWnjEoMmRKTcfNL08dL/7J4+Iz37YlZ8mqKB2AIoLJIiiAXPt9p/3OqlbeG+8Rm0G69w9NXlCVUyOwRFkJs1klDlFYuVnDx7SH+mbOo8lU2ePaKdhMYY7TzUrVNnonFceOdQt7KeSIyUiEwmo4aGBknS7bff3qfcHQAQb55vdeQ0LX3zKsuluz+V0IcW5G5PUCGCQjPGyEhaMLNc86Yk+33MtHEJzZnc//fOf55/2uRp54HwXG/vOmT1/BaONWFHbAEUHu2zEHnWWnm+9A+/zop7hSPjGGn5EldLF7qyNti5BYi2/O9Wxayr5FbVqnNfswb64CYmzFD5zPkjfq3dR7t1tCU6AUKPJ+082K2rZwffRgtSU1OT7rjjDknS8uXL1dTUpA0bNmjp0qWX/HPNzc2qra2VJN188829f6apqan3+6lUSl/4whf08MMPS8oNXXzwwQclSUuXLtUzzzwzpOccSDqd1qpVq7R169be3sDDWSsAoH/WWlkrNf2KweqSNLne6N/ellBtFckQFFf+92vmhISqKxxtT3cpe+4zOKHW1RXTkpeMdZ/fktXr74bvg/urt3zNnORr/gwjh82NoURsARQeSRFEnjFG617J6vSZoFcSTpVl0l2fSGje1NzFE8EKxkpiwgxVVdSoY9cbstm+00fdukmqmHP1iJJ01lodPJVV+kS2kMstCSfPeDp8Oqup9QP3QcbYePvtt3XfffdJygUS+TL3wXr/PvDAA6qvr+/zmNWrV/c+x8qVK7Vy5Urddtttamho6A1apFxwdO+992rWrFlauXLlkJ9zIA0NDXrmmWf6HZI4mucFgLgzxuhnv83qxMWH1thZ0GD0hY8l5DpUoWPsGGM0rtrRDZdV6O19XUq6RgtnlvV+rz/WWr36jq9fvhm+hIgkWUk/+nVuvkh9tSUxEkLEFkDh0T4Lkeb5VvuO+Xr9nXBevARtUp309c8mNWeK4QYrxpwxRk51SlULb5ZTler9ulNdr8rLru99zHBYa3U84+m9Iz2FXGpJee9It7p6LG20ApROp3vL2/MuVebe1NSkjRs36qGHHurz9Y0bN+rZZ5/t87WVK1cO+DznBy3Dec6BXPhzFOp5ASCOPN9qR9rXq8Qm+tg1jv7oloQSLgkRjD1jjMqTRjdeVqFrZ5fLmIHjCt9a7Uhb/eTlcFeYd/VIP3g+K58QIXSILYDiICmCSDOS/nmTJ877w3flTKP/8OmkUlUEKgiOMY5MMqmqBR9SYtxUORXVqrriRsk4I0qItLb72nGw+9IPDjHPl7YfiPbPWOo2bNjQW96et3z5ckka8MJ+zZo1WrZsmVKpVJ+vL1y48KLnygcnTU1NvV/LZDKqr68f8XMOR7GeFwCizPetOrultf8avUrV4Ui60sqPufrkjblh1g4brxAQxxg5RnKcQRIivtXBE1ZNv4pGK+5jLVa/eMNj81TIEFsAxUH7LESWb61+s9XXsRZO+MP10WscffIGV1YiUEHgjHFkZVV52fWyXlZyhp8Q8a1VR5fV1v1dkQhoLiXT4St9IquGiQmqvALQ1NSkt99+u08g0dLSIim34+lCmUymz/DE8z3++OMXfS2VSmnp0qVqamrqDWLWr1/fZyfXcJ9zqIr1vAAQdY5j9A+/6VF7V9ArCU5dlfTl2xKaUs+1CUrDYNfJnm91uk36X7/IKhvuIpE+Nm3zde1cR1PHs/kxLIgtgOIgKYJI8n2rTLv04psRunoZAwlXWnGzq2vnuZJylTZAKegNWJzhz8rwrVV31uqtfZ2xGmi693iPxte6qionuTmW0um0li1b1qcnb97q1av19NNPa8OGDb27uyT19tW9cDfWYFauXKkHH3ywt5x+//79fXZXjeQ5h6JYzwsAUeZbq5e3+3r3YAx2ZgxgfK107+1JVVeIeQYoeZ5v1dElPfPzHnVErADbWunH/+rpG5/ldmAYEFsAxUP7LESS4xj98+asesiJDFl5UvrKsoSunsNhAaVrJC2zPF96a2+XumPWrcJaafuBGG9HDcizzz6ru+66q9/v5cu/161b1+fr+Z1R6XR6yK9zfsl8Op3WNddcM+rnHIpiPS8ARJXnW51stfr56/ENTCbWSV+7I5cQYWc6Sp21VllPemZjVq1ng15NcRxrsfrl72ijFQbEFkDxcPcTkeP5Vm/v8WK9E2u4KsukryxPaOZEw84tRIa1Vr6V3t7bpY7ueB4P2rus9h/PEvCMof4GIeY1NjaqoaGh3zL3ZcuWDToosT8rV67UD3/4w4t2h43mOYeiWM8LAFH17K+8SLXfGY4p9UZfuz2pynISIgiP1rNWre3Rvn7+9du5VuMek9dLGrEFsQWKh6QIIsfzpHWvxDTqGIGqcumrtyc0dRwJEURHPgnQnO5SW2eMemb1I32iR91ZS2JkDDQ1NamtrW3QxyxbtkxSbmDi+b71rW9JypXBn6+5uVl1dXX9PtfKlSuVyWR6ewpfaLjPmclk+n2eC78+krUCQFxtfM3T0dPxPAdPG2903x0JlZeREEF4GGM0MWX01eUJVZYHvZri8a30D7/xRJfd0kVsQWyB4jKWuySIEGutNrzm6aXmeN8EHaqaSumryxMaX2sIVBA52w906VgrCVJJmphy1dgwsqius7NTe/bs0dy5c1VRUTHoY8/+0/fknTwyotcZa+6Eqar+g68U5Lmam5u1Zs2a3h1OjY2NWrt27UWPe+CBB7R582ZlMhmlUinddNNNuuuuu7R06dLex6xevVptbW1qaGhQKpVSQ0NDn+9f6LbbbtNjjz2mxsbGAR8z2HOm02mtXr26d13Lli3TXXfdpYaGhou+fv/99/d5neGuFRjIcI4zQFh4vtXeo1bf35hVHAPu6RNyN5WTLjNEEE6eb3Wi1erp9dnIzRU53ydvcPWRa5wxm0FIbHFpxBbEFhidoR5nSIogMnxr1dYu/fe1PbEtTx+OmkrpvtuTqq9h5xai570j3TpwMmZDRC7hujnlSlUNP+AZ6gWF9X0ZJ1wFqGFc84VWr17d7+BFIExIiiCKsp7V/3dtj1oiOpNgMFPGGd13e0JlCRIiCDfPtzp22urpDVl19QS9muJIuNI3fz+pcTVj83kltihtxBaIgqEeZ8L9aQXO4xijDa/Ft1/vcFRXSPcuJyGC6LHW6sDJHhIi/dh1uFvF/LSHMQAI45rPl8lkNGvWrKCXAQC4gLVWL/zOi2VCZFJdrhKdhAiiwHWMpowzuvtTud/pKMp60j/8JltybbTCeJ0exjWfj9gCcRPuTyxwju9bHTzh6+09tM26lMryXKAyrpaECKLFWivfz83QwMXOdlkdPMXQ9TBrbm7u02t3/fr1uv322wNcEQDgQr5vdbpNsWznO75W+urypMqTJEQQHY5jNGOC0b/7ZK4dXBSlj1tt2ubLJ06IFWILxB1JEUSC4xiGqw9BRZn0lU8lNCHFDBFEjzFGxpGum1MR2YBltPYd65Hni8RISK1bt04bN26UlNvJVVdXp1QqFfCqAADncxyjf96clReznEhdtXTv7UlVlrPxCtHjOEYNk4y+fGtCbkTvoj23xVPmbC6xi3ggtkDcRbQAEHHi+VY701b7jnHyHkxZQrr7kwlNGWfYuYXIcoxRRVkuMfK7vZ2007tA1pd2H+3W/OkjG7qOYN1///2SpKeeekqSdN999wW5HADABTzfats+X+8djldcUpaQ/u1tCVVXkBBBdDmO0dxp0mc+5OqfNkUvyOjJSj/+16y+ujwZ9FIwRogtEHckRRB6RtKG15gfMBhjpC9+IqHpE0iIIPocY1RVLl09q1xv7u0SRRF9HT7tafp4X1XlZthD1xGsVCrF4EMAKGGeL617NXo3SwdjJH3uwwlNqiPOQPQ5xmjxfFdHTlm9vCN65WB7jli99o6nGy53+DzHALEF4i6ihX+IC9+3+u0OX6fagl5JafvUDa4un06ggvgwxihV6eiKaWVBL6UkvXuom4QIAAAFZK3V81s8tbUHvZKx9fHrHDXO4QYq4uWOD7q6bFo0f+d/8YanbPTyPQBwEZIiCDVrpV+/Ha/dWMN1/TxHH7nGleEGKGLGGKNp4xKaPp6iyAtlOnwdbckyTBEAgALwfauWM9LL2+N1J3HhbKNbF3GdhRiyuU4M42uDXkjhne2UfvWWxwxCAJFHUgSh5ftWr7zjq60j6JWUrhkTje682eWCBrF2+dSk6qs53V1o99EeWosBAFAAjmO07tV4DVefOs7o8x9JsMECseQ4RsmE9G9uS6g8giM4NjX7OtMhPt8AIo27RAgtK+k3VIkMqLZS+je3JmSMqBJB7DU2lKsiyefgfN1Zq4OnskNOmpJcBVAsHF8QZp5vtfeIr+374/N7XFWeuxnsOKIdJ2LLdYwm1Bp94aO5mDtKejxp4+teUT/fnPsBFMtQjy8kRRBKnm/12ju+MjHr2TtUCVf68m0JVZaL/r6IPWOMHEe6Zna5XM56fRw4celqkUQi1xajq6trDFYEII7yx5f88QYIE8dIP30lPhu1XEf6o1sSqqnM3RQG4sxxjObPNLptkRv0Ugruzfd8HTnly/cLm7wgtgBQbEONLbg9hNBilsjA/mCpq2njDYEKcI5jjCrLjK6ayeD18/V40qHTg1eLJBIJVVdX69SpU/I8jrsACsvzPJ06dUrV1dUkRRA6nm/1xi5fR07FZ8fzHR9wNWsycQaQZ4zRx651de3caN1es5LWveIVfJMlsQWAYhpObEHkgdDxfKs33vXVejbolZSmmxsdXX9Z9HaqAKNljNH4GldzJie191hP0MspGekTWU0fn9Bg4c7EiROVTqe1Z88e1dXVqbKyUq7r0poPwIhYa+V5njo6OtTa2irf9zVt2rSglwUMm+9Lv3gjPjf1PnClow8uIM4ALuRbqxUfdnUiY3XoZHSSpLuPWL170Ne8aYVNhBJbACikkcYWxtLIDyHj+1bfWdujljNBr6T0zJ9h9G9uS3AxAVzCtnSXjmficxPjUi6fltS0cYlB+wZ3d3fr2LFjam9vZ1cXgIJwXVdVVVWaPHmyysqo5EO4+L7Vr97y9fzv4nFOnDHR6P47ErTmBQbg+1ZnO6XH/qlHnd1Br6Zwpo03+sZnCz9NntgCQKENN7agUgSh4vlWb+72SYj0Y0JKWvnxhKw06I5vIO6stVowo0wd3Z0608m+AOlctci4wS8JysrKNHPmTFlr1dPTI9/3x2h1AKLIcRwlk0k2ciC0PF/atD0eN/ISrvT5j+biDAD9cxyj6gqr25e4+seXonNsOHzKqnmfrwUNha0WIbYAUEgjiS1IiiBUXMdo0zZOlhdyjPSFjyaUcDXoTm8AOneStLpqZrlee6/zkoPG46Crx+pIi6cp9e4ljyHGGHZ0AwBizfetXtnpqyMmc4Jvud7V+FriDOBSHMfoxitcbd3r692D0Qkynnsjq4WzCl8tIhFbAAhOtCZBIdJ832rv0XgNMhyqpY2Opk9g4CEwVObc4PU5k4pzcR9G+4/3UGUGAMAQWEkvNUdnJ/hgZk40+sjVDgkRYIh832rFhxOqiNB9/uOt0pu7fXk+92IARAdJEYSG45jYBB/DMalO+uQihpIBw2WMUcPEhGorOBVKUmeP1bFWTz6lMwAADMjzrbbs8pVpD3olxZdwpT/8aELcBwWGznGMqsul25e4QS+loF74nccGKgCRwp0ghIK1Vi1nrHakuSI/n2OkP/xIgiEiwAhZSQtmlomcYs4+qkUAABiUY6TfvB2PjVr5tllUowPDk2+jdcWM6Hx2TrVJr79LtQiA6CApgtDYtM2j9/8FaJsFjI5DG60+OrqtjmeoFgEAoD+eb7V1r6+TbUGvpPhomwWMThTbaP3qbY/NZAAig6QIQqHHy+1KwPtomwUUBm20+tp/vIcbIAAA9MN1jH71dvRjEtpmAaMXxTZaLWekHfst1SIAIoE7QCh5vm/1+ju+unqCXknpoG0WUFi00Xrf2S6rU21UiwAAcD7Pt3r3oK8jp6J/fqRtFlAYUWyjtXm7x7EBQCSQFEHJcxyj3+6MR9/eobqZtllAQdFGq69Dp7NUiwAAcB7XMXrxzejHJLTNAgoram209hyxOtbis4EKQOiRFEFJ832r9HFfJ1qDXknpmFQn3XYDbbOAQqON1vtOtXnqzhLoAAAg5WKS/cd87TsW7XNjvhqdzjhA4eTbaC27MTpttF5q9mlaASD0uPODkmaM9No70e/bO1S9bbMAFAVttHKspCOns7LsAAMAQI5j9MsYVInceIWjCSnaZgGF5jhGi+c7mlwfjc/WW7tpbw4g/EiKoKRlPWnrXpIieYvn0zYLKKZ8G62ZE0g+Hj6dpSINABB7vm915LSvdw9Ge6NA0pVuXeQq2j8lEBzfSp+8IRrVIj2e9MpOXz5lZQBCjKQISpbnW23dyw6EvGSCQAUYC8YYzZqYVCIaMcuIdfZYnT7jUS0CAIg1xzF68c3ob9K6aaGjqgoxSwQoEtcxumqWo4ZJ0fiM/XaHJ3poAQgzkiIoWa5j9Mau6AcgQ7X0KkdV5QQqwFhwHWnWRIauUy0CAIi7tnar5n3Rjkkqy6SPXesSZwBF5vlWyxdHY+dV61lp+34rj2oRACFFUgQlyVqrljNWe49wgpWkynLpo9cyXB0YK8YYzRifUFki3p+5E22eejyOwwCAePJ9qzd2+Yp60eRHr3GVjMZ9WqCkuY7R7CmO5s+IRoyxeZtHa28AoUVSBCXJWum1dzxaRZ1DoAIEwEhzJse7WsRaBq4DAOLLcYy27Ir2gPVUVa51lsONTWBM+L7VssVuJDpP7T1qdfS0L59YAUAIkRRBSXIco9/tjnaZ+lDVVeVaZxGoAGPLMUZT611VlsX7s0cLLQBAHPnW6sAJXycyQa+kuG653hWneWDsOI7RlHGOrp0XjdtxLzX7kUjwAIifaByFESnWWh066avlTNArKQ23XO8ywAwIiJU0d0q8q0U6uq1azzJwHQAQL0bS6+9Ge5PWxDrphisc2t8AY8y3Vp+8wZUbgTtyb+3x1dkT9CoAYPgicAhG1Fgrvb0n2gHIUE0iUAEC5RijSamEaivjfbo8RLUIACBmfD/6McknFyUiPy8FKEWOMaqrlhbPD3+MkfWkV3b48hm4DiBkwn8ERuQ4jlHzvmgHIEP1yRsS4toCCJZvrebFvFrkeMZTloHrAICY8Hyrbft9dXYHvZLimTHRqHEOm6+AIN16vauyRNCrGL1X3/Fo9w0gdEiKoKRYmxvUdaot6JUEb+ZEo4WzCVSAoDnGqL7a1bjq+J4yrZWOtXoMUQQAxILrGG3ZFe1NWrctcuWx+woIjDFGFeXSh64Kf4zRckY6eMKn3S6AUAn/0ReRQuus9y1fTKAClAprreZNLQt6GYE62ZaVQwstAEAMnO202nUoutfh42ulK2aw+QoImpH0oQWuonCJ/dYeX9E9agKIIpIiKCm0zsppmGQ0ZyqBClAqjDGqqXA0via+p83TZ30StQCAyPN8qzd2+ZFuYfuBK136/wMlwBijVLXR/Bnhj/u37fPZQAUgVOJ7dwclx1qrE62+jrcGvZLgfWiBw81HoMT41mr6+PjOFrFWOnWGFloAgGiLeuushJsb7kz/f6A0eL7Vh65yg17GqJ0+Ix06SQstAOFBUgQlw7fS1r2cQKsrpKvnUiUClBrHGI2vcVSRjO9n80TGYwcYACCyrLU6fMrXsZboxiTXzHVUHt89HkDJcR2jK2Y4Gl8b9EpG7609vsiJAAgLkiIoGa5j9M7B6O7KGqobr3Ai0VMUiKpp4xJBLyEwp8547P4CAETa6+9EOx656SqHm5ZAifF9qyVXhr9apHmvTxUagNAgKYKS0d1jdeB4vK/QjZE+uMAVlxFAaTLGaNr4RGwTl1lPam2nLB4AEE2+ze10jqoZE4ymT6B1FlBqHMdoyXxHiZDnRU6fkQ6fIlYAEA4kRVASfN9q12Eb6YGGQzF/hlFdtZGJ6x1XIASSrtGkVMgjllE4kfGCXgIAAAXn+VbvHrRq7wp6JcXzAeYWAiWroszomjnhv0X3Ni20AIRE+I+4iARjpF20ztKHrnIJVIASZ63VjPHxbaF1ss0jcQsAiBzHSDv2RzceqSyTrpvH3EKgVPm+1YeuCv8tuq200AIQEuE/4iISjDHadSi6QchQjK+VLp9uCFSAEmeMUarKVU1FPD+rnT1WZzspiwcAREvU45FFlztyiP6BkuU4RjMmOpo+Idwxxqk26chpYgUApY/LIpSEljNWp9qCXkWwlsx3Y98+DAgL31pNG5cMehmBoYUWACBqTmasWs4GvYriMJJuuoq5hUCp83yrD14Z/tt0tNACEAbhP9oi9DzfaueB6O7KGoqEKy25knJ2ICwcYzSl3pUb07PoibYsLbQAAJER9Xhk3jSjcbXMLQRKnesYXXeZo4qyoFcyOrTQAhAGMb2dg1LiOtEuVR+Kq+c4qijjogEIE8dIU+vjOVvkTKdVd0+8j9sAgOhwHRPp+YZXz2HAOhAWCddo/oxw36o7mZGOtdBCC0BpC/eRFpGx72i8T5YfXODIJ1ABQmd6jAeun2jz5BPoAAAiwPOt9kQ0HjGSrppFRToQFp5vtaAh/J/Xt3bTQgtAaSMpgsCdbrNq7wp6FcGpqZQaJjmUlwIhY4xRVbmjyphWebW2+3JowwEACDnfWu0/atWTDXolxTFtglFNJedrICxcx+jKBif0bXp3HbLc4wBQ0kJ+mEXYeb7V3qPRLVUfiitnOpSVAiFlrdWEWjfoZQSi9Wy8j90AgIiw0s4It866qoHWWUDYlCeNZk8Jd0Lh0EmrnizHHgCli6QIAuUYaf/xeJ8or5rlUFYKhNjEVDyTIl1Zqy7migAAQs5xjHYdjO7F+MLZRmzWBsIl10Ir3LfrfCsdOG7ZAAqgZIX7KIvQM8YofSy+J8mkK10+3VBWCoSUMUapSkeJeOZFdPqsz1wRAECone20Ono6muey+mppyjhHhnaXQKi4jlHj7PDfrttz1IpCNQClKvxHWYRad9bqaEt8z5KXTTdKuAQpQJgZYzShJp5ZkdaznjiCAQDCyvOt3j3gK6rRyJUNtOkFwqqu2mhKfbivtPcd9eWyARRAiSIpgsBYa8+VUwa9kuAsoMcvEHp+nOeKtPvsPgUAhJbrGL17KLrX4rTpBcLL960WNIT7Ojt93MrnfgeAEkVSBIHxrbQ/xq2zjHKBCjsngHBzjNH4WldxzA10dFv1ePE9jgMAwm/XoWjOxypPSnOn0qYXCCtjpIUhb6HVnZWORLQ9IYDwC/cRFqHmOkYHTkQzCBmKGRONqisIUoAocB2j+qp4nlIz7T6tOQAAoWOt1ZFTvs52Br2S4rh8umHzFRBixhjNmOiopjLolYzOniOW7hgASlI87+CgZMR51wCts4Do8K3VhFQ8W2i1dXiR7cUOAIgu30rvHozuGeyqWcQaQNhZa3XlzHDfttvLXBEAJSrcR1eEWnfWqvVM0KsIzsLZRlwbANHgGKOJMZ0rkunw5cSxdxgAINSiXrV+5Uza9AJhZ600P+RJkX1HSc4CKE3hProi1I632NjuLh5XI02udxhQDERIedJRTQxb4rV1RPeGEgAg2g6djGY0Mq5GqiyP3zUJEDWOYzRrUrg/y+1d0slMNI+1AMKNpAgC4flWh0/F98R4xQyHHvxAxFhrNb4mftUiWU/q7CYxAgAIl85uq9MRrVqfPiHcN1EBvK+2yqiqPOhVjM6eIz7t/ACUHJIiCIQx0tGW+J4UZ04y4poAiJ7aynieVlvbffkkegEAIWGt1cGIVolI0oyJzBMBomTGxHAnOvcetbTzA1By4nn3BoFzjNGxGA9Zb5houCgAIsYYo1RMkyJnu3xxRAMAhIVvpYMnohuLzJjI7EIgKjzfakbIq7/2HaWqHEDpiefdG5SEuFaKJF1pQl24L2oA9K8s6SgZvw5a6uiyzEgCAISG6xgdjPCQ9RkTDOdlICKMpOkTw33r7vQZ6UxHPO//AChd4T6yIrQ6u63OdAS9imBMHW/kEKQAkRXHFlodzBQBAIRMlIesV5QRawBR4ThGDSFvnyVJB09a5qoCKCnxu3ODknAiE9+T4fQJht77QET51qomlkkRjmkAgPDo7mHIOoDwiMKw9WMtVj77qACUkPjduUHgfN/qVFt8b6DNmGhETgSIJiOptiJ+p1bfSl09RDkAgHA4FuE2vgxZB6Ip7MPWj7dYOfELkwCUMA5JGHPWSi0R3Zk1FAxZB6IrzsPW27soiQcAlD7PtzpyOrrnK4asA9Hj+Tb0VWDHWplBCKC0xPPODQLlOFLLmegGIoNhyDoQfXEdtt7e7SueR3YAQJgYIx2NclKEIetA5BhJMyaE+/bd8QhX6AEIp3AfVRFKxhidjmlShCHrQDzEc9i6FUc3AECpc4yJbPsshqwD0eQ4Rg2Twv3Z7uqRznZG89gLIJzid9cGJSGulSIMWQeiL7bD1rt8dqYCAELhaESTIlPHcx4Goqq2yqiyLOhVjM7R07TbBVA64nfXBiWh5WzQKwgGQ9aB6IvrsPWObg5uAIDS19ltdaYj6FUUR10VG7CAKEtVhTvxeazFyveDXgUA5MTvrg0C19Fl1ZMNehXBmMmQdSDyjDGxbJ/V2c3OLwBA6Ytq6ywpt5PccsMRiKzaqqBXMDqn2qwoLAdQKuJ31waBaz0b3UDkUuqquQIA4qAsEb/PupXU1RPf4zsAoPT5vo30bMPaSokBX0B01VaG+wN+qs3KYZMogBJBUgRjri2i5eqXknSl8iQXAEAcGGNUlgh6FWPvbBfVIgCA0uVbqa096FUUT6qaqnQgqjzfhr5S5HRb0CsAgPeRFMGY8n2rs53xvGEW9gsYAMMTx2qRjm6fuUkAgJLlGOlMR3RPVHXEG0B02fBXikS5Ug9A+JAUwZjyrdTeFfQqghH2CxgAwxPHpEhP1tK2AwBQshzHRLpqvSbkQ5gBDMw4ublBYdadldq7SIwAKA0kRTCmjMkNWo+jmsqgVwBgrFhrVRbDdnlZj5wIAKC0RbVSxHWkyjLOwkBUOcaorjroVYzeqbZoHoMBhE8MO54jSI4ZWaXI5nVrNHX2Is1tvPWi7+1pfl7bX/2xKqrq1dneooqqet3yhf82rOd/48Wn1XJst47s26KOs6c1d+Etw36OS0lVGfnWyjEEK0DUWUnlcawU8awMxzgAQAmLaqVILRuwgMhLhbxSRJJOZqymj2fgOoDgkRTBmDLGqGOYSZHO9ha98KP/pBVf//uLvrd53RrtaX5eX3p4fZ+v/fi7X9TnvnHx4/vzwg//VIs+fq/Gffze3tdb+90v6i+/MUXfWL1TFVX1w1vwAGqrjHxfctyCPB2AEhfH9llZj51fAIDS1tYezXMVrbOA6KuuCHoFo5dpz7VVp20NgKBxHMKYG24PyS0vPt3v1w/v3aIXfvSfdPu/+26fr990x0Pau+0FbX917SWfe/ura3XVBz6vcZPn9X6toqpeK77x973JkUKprcy1DwMQfUZxTYoEvQIAAAbm+VYd3UGvojioFAGiL+EaVZQFvYrR6ey23BcBUBJIimDMDad91p7m5zVn4cUtsyRp08++ramzF/VJaORdteRz2vLiU5d8/sN7XtO0OYsu+npFVb0Wfeyr2rPtBXW2twx9wYNIVRu5lIgCsWCMUUUMZ4r0+NHcfQsAiIaznUGvoHhSVUbWch4Goi7sLbQ6u9ksCqA0kBTBmOvsHvrF+pF9W/pNWkjS3m0vqH7S3H6/N3XODdqz7YVLPv+WX/2N/m717QM+hyQd3vP6EFc7uLqqgjwNgJAoS8bvFEv7LABAKYvqkHVJqq3MteoFEG1hrwrr6hZzVgGUhPjdsUHgurNDe9wbLz6tm+54aMDvD1bBUVk9XlKuxdZgpp1LfPSn69zzV5x7rtGqqeTED8RJMobzg7Ke2KUKAChJ1lq1ng16FcWTTEicgYHoS4Z8MnBnD0cqAKUh5IdThNFQes6fPra7N7ExkKEMQG85vmfAShNJfQa097cGSYP++aFKuFJFGUkRIE6MMUq6Uk/M5mx4fu6YBwBAKfF9qS3ClSKOyc00AxBtYe/I3RnRuU4AwodKEYy5oSRFdry2VlctWTHoY6bNuaG3muNCLcd3j2BlfW351d9o0ce+OurnkRT6YWgARibphjxqGYEsc0UAAKXISG3t0T1HOUT2QCw4Ic+KdPYEvQIAyOHSCWPuUkmR7a+u1YLFgydEJOmmOx4acG7IoXNzQDrOnhr2+iTphR/+qeonzdUtX/hvI/rzF4rhfVEAiucQwWw2ujecAADh5RiprSPoVRSPY0SpCBADbsjv4nUNY8YsABRTyA+nCBvvEjuIO9tb1HH2lMZNnnfJ55rbeKsWfeyreuGHf9rn69tfXau5jbdK0iVbcPXn8N4t2vKrv9GXHlo3pBZdQ8HOLSCe4pgUiVu7MABAOBhjIj1onXgDiIeQF4qog/ZZAEoEM0Uwpi41f3fLJYarX+iOu/9Kb7z4tN548ener81deIuO7PudJKmiqm7Ya1z7V1/Ulx7eMKTEzFCF/cIFwMgYGcVt7GmPZ2WtlYljRggAUNK6Ity2Jey7xwEMTdgToFE+DgMIF5IiGFODFYoc3rtFU2cPf6j5DR+/96Kv5dtqTZt747Ce6+9W3647/t13CzJc/Xxhv3ABMDJxzAtkvVwCPI4/OwCgtF1qg1aYRflnAxAd1krdWauyBMECgGCRFMGY8v2Bv9dyfI+2vfKjPlUfknqHqW/62be17ZUfqbJ6nO64+68GfZ0je9/Q1NmLhtX+at33v66b7niot/VWIYV9GBqAkYljYsDQ0xwAUKKinDi4RJdiABEx2D2VsOjukcq4GwkgYByGUDKuWrJCVy25eMB6Z3uL/vIbU7T09/5jv9/vz/ZXf6xPfP6/Dvm1N69bo6uWfO6ihMjpY7vVcnzPqBMl5ESAeOKjDwBA6Yhy4iAKN0oBXFoUjmOdPVY1lURKAIJFUx+MqUK2kdr+6lr95Tem9Pv1iupx/bbVGuh5ps5e1G/i48i+36l+0txRr5UgBYinCMQsw0Z4AwAoVZGvFInwzwcgx4vAvYXOrqBXAABUimCMjWQA4OljeyRJHWdP9fl6x9lTmjbnhj5fO7x3i1740Z/qSw+tu+h5fvzdL+rIvi36xrd39Hn8lhef0oIln9Pp89p25Vt2bXvlH/TV//zy8Bd9AT/KERiAAcXyo09WBABQoqKww3ogbMIC4sGPwIGsg6QIgBJAUgRjyh1GH6nDe7do08++rZbjuaTIL3/0n7Sn+XnNbbxVN3z8Xt3w8XvV1d6iF374p+psb1HH2dMaN2muvvqfXx5wlsiFX/+71cvV2d7SO5j9QoWoEpEIUoC4imNShJEiAIBSFeXzsm8pFAHiIAI5EXX2WPm+ZfYqgECRFMGYc8zQTuTT5izS577x94M+5qY7Hhry6/b3XH/y3aND/vOj4UXgwgXA8PkxvT1hRWIEAFB6onxW7s5y7gXioCcb9ApGz3GMDAcsAAFjpgjGXMINegVjj0oRIJ6ivCN1MMQ4AIBSZCN8Td7Wbgs6vxFAacq0hz/ASLiSISsCIGBcNmHMjWSuSNhFYRgagOGLY1KE+AYAUKqifFpu67DcZARioK0j6BWMXjKGG2UBlJ4Y3p5G0NwYngA7u4NeAYAg9NA7DwCAkuFHeLdCFG6UAhhc1rORuLcQx+4hAEoPSRGMuUQMf+s8X+roim4QBuBivrXKekGvYuyxRxUAUKoinBNRWwRa6gAY3NnOoFdQGCRFAJSCGN6eRtDKkvG8ZdbWQaACxElPNqaf+Xge4gEAIRDlpMgZKkWAyIvCPBGJpAiA0kBSBGOuqjzoFQSj9axkoxyJAeijO6ZJEXIiAIBSFeVLcSrTgWjzfavWs0GvojASLhEDgOCRFMGYq4xpUiTTbuUTpwCxYK1VZ098P/AMegUAlKIoJ0Uk6QyV6UBk+TY6bfJc7kQCKAEcijCmrLWqKo/nzbK29ugHYgByrI1vpYjrxPMYDwAofVHP2bdEZBc5gIsZE52W3LTPAlAKSIpgTPk2vu2z2josOyKAuDBSd0wrReI6NwoAUPoqI745q63dyqM0HYgk1zFqaw96FYXBfREApYBDEcaUtdEPRgbS1m5pKQPEhGNMbCtFkvQIBgCUqKhvzmrrkBTPyw8gFqJSKUJSBEAp4FCEMWVM9IORgbR1BL0CAGMpvkmRoFcAAED/qiuinbjPtFsZInwgsjJUigBAwXAowphyjGI8UySeN0iBuOqKYfushMOQdQBAafJ9G/nNWZl2K4fzMBBZmQjcUzBGcphBCKAEkBTBmDLGqKYy6FUEg0oRIF7iWCmSTBDgAABKk7VSVcQrRQ6fit+1BxAXmXarzu6gVzF6Ce5CAigRHI4w5uqqox2MDMTzpY5uAhUgDqy16vGCXsXYKyMpAgAoYVGvFGk5I3USbwCR4/tW6WPR+Gy7tNoFUCJIimDM1VbmSibjqKUtGhcyAAYXx9ZZEkPWAQClKy6zDQ+esLI2ntchQJQdOukHvYSCqI7BcRhAOJAUwZhzHKNUTFtoHThh5fkEKUCUWWuV6YhG0DJcyYThRgwAoCQ5jlFNZfST9wdOWBFuANHiOEYHT0bjgx3XziEASg9JEQSiviaeJ8KDJ62YKQZE35mYJkXKElI0wjUAQBTVVAS9guI7dNKXS8ABRM6hqCRFYnovCEDpISmCQMQ1KXLopJWJa+8wICaMMWrrjGdSJOkasiIAgJIV9UHrkiKzmxzA+zLtVu1dQa+iMOqqRPcMACWBpAjGnOdb1dcEvYpgHD1N+ywgDuJaKZJMmNjOjAIAlL6KsqBXUHwMWweixfetDhyPzme6voZNVABKA0kRBKI+pn0kPV861sIVABBlnd2+svHMiagsYaiGAwCULNcxKk8GvYriY9g6EC0HIzJkXcrNFHG4EwmgBHAowphzjDSuNr43zQ4cp1oEiKo4D1mXckkRAABKWVV50CsoPoatA9HhOCYy80QkaVyN2EQFoCSQFMGYM8ZoYiq+J0GGrQPRFtfWWZJUnuTgBgAobXGYK8KwdSBaDp6ITlIkFdOuIQBKD0kRBKKuWkq6Qa8iGAxbB6IrzkPWy5OGGzAAgJJXXRH0CoqPYetAdERpyHpFGZXlAEoHSREEwhijiXXxPBkybB2ItrhWilSXx/OYDgAID2utxtVE/3zVckZq7yLeAMLO863Sx6LzWa6jSgRACSEpgsBMGRfPEyLD1oHoivOQ9apyh6GuAICS5vuKzcasnWmfjVhAyDlGeudgdIKLuuqgVwAA7yMpgkB4ntWU+ngEJP1h2DoQPXEfsp5LigS9CgAABuY40qSYJEV2pJkrAkTBjnR04ou6asMmKgAlg6QIAuE48a0UkaT0cYatA1HUFuOkSHW5kcOBDQBQwowxmhyTjVnvHmQTFhBm1lodPGl1tjPolRROfbWRH99wCUCJISmCQBhjNG18PAKS/rxz0GfYOhAxxhidbPOCXkZgqsq5pAAAlL7aSinhBr2K4uvOSnsOW/kkRoBQslbati9aGYS6akncBgFQIriDgcDUVhmVJ4NeRTDOdEgHT/iUjgIR0tHtq6M7np/psoSUcIlwAAClzxijCbXxOGdt2++LfVhAODmO0Y50tGKL+hpDWz8AJYOkCAIVl/L1/mzb79N/H4gI31qdyFAlAgBAGEyoC3oFY2Nnmup0IKxazlgda4nWDYOJKY5HAEoHdzEQGN9azZgY35Pijv2W/vtARDi0zqLyDQAQCp5vNTkmw9Zb26Ujp6lOB8LG86227Y9W66yqcqmmMh7HXgDhQFIEgbFWmjUpvifFoy1WrWcJUIAoyHpWre3RClyGo6rcUPkGAAgFI2nKuPjEINv2Wc7RQMi4jtGOiCVFpsZ4piyA0kRSBIFxHaPZU+L9K7htny+P4YdAqPnW6kSMq0QkqbrcoWc5ACAUHMdo+oT4xCA70j7V6UDIdPVY7T0arfsE08Yb+dz7AFBC4nM1iJJUV21UUxn0KoKzI+0zaAwIubi3zpLySRGOZQCAcBhXKyXcoFcxNg6dtDrTwY1IICw832pn2lfU8gfTxhtF7EcCEHIkRRC4hhi30Np71Kq7h0sDIMx8a3X6THyTIglXSibiexwHAISPY4wm18fn3NVMdToQGq5jtD0dvc/rzImGDaEASgpJEQTK860aJsX319DzpZ0HCFKAsLLWquWsLy9aLX+Hpa4qJlttAQCRYa3V1BjNFWneR3U6EBZZz+qdA9EKLhKuNL6WYxCA0hLfu9EoCY6RZk+O98lx+35LkAKE2MlMfKtEJKmuypHPBFcAQIj4fryG/u45bHWqzXK+Bkqc51v97j1fXT1Br6SwptQbZhsBKDkkRRAoY4xmTDSK8/nxnYM+A8eAkDLG6GSMW2dJ0rhqRw7zRAAAIeI40vQJ8Tl3WUkvb/cUn58YCCfXMfrtjmhViUjSzElGlqQsgBJDUgSBS7hG02IUlFyos1vafcTSQgsIGWut2jo8dcV4LpDrSNUVXEoAAMLFGKMZE+K1MeuNXfFu9wmUOt+3OnDC1+FT0YstGiaZyA2OBxB+3MlA4Hzf6vLpMYpI+vHbHR4ttICQMcbo4Kls0MsIVKrSkaFKBAAQQslErmI9Ljq7pTffY5YhUKocx+jlbdHMXM6e4nC/A0DJISmCwBkjXTEj3r+KO9NWbe2WklIgRLKe1fHWeLfOqqt26U8OAAgl37eaNy1eN+l+u5OB60Cp6uiy2rovekmRqnJpXA3HHQClJ953olESjDFqmGRUlgh6JcHxba5ahHuLQDj41urw6Wzsy8Drqx36kwMAQskY6bJp8QqHD520OniCeYZAqfF9q1ff8ZWN4H6rmZOIFgCUpnhdBaJkuY7R3KnxPlm+9m70doUAUeUYo0On4906yzFSLe2zAAAhZYzRrMlGCTfolYytl7f7cqgWAUqKMdKrOyOYEZHUMMmhbR+AkkRSBCXB860umx7vX8czHVLzPvr8AqXOt1anznjq7I73Z7W20pFDQgQAEGIJN1exHidv7/Vjfw0DlBLPt3r3oNXpM0GvpDhmTTYiDwugFMX7LjRKhusYXTmTX8ff7qDPL1DqHGN0KOYD1iWprtphDhIAINQ832re1HjFIFlPevUdWmgBpcJ1jF7eEc0qEdeRGiYZKssBlKR4XQGipE1IGdVVBb2KYO09anW81WdwMVCirLXq6vF1si2agctw1FfFrN8IACByHCNdNj1+N+te3enRQgsoAdZatZ7NVYpE0ezJRmUJjjUAShNJEZQMa60un8Gv5OZtPoOLgRJGlYhkJKWqmCcCAAg3Y4xmTjRKJoJeydg61Sa9c4C2vUDQrKTN2z1FdU/klQ3MEwFQurgDjZJhrdQ4m1/JN3f76mETOlCSrKTDMR+wLkk1lQ6t/gAAkeA4RrMnx++c9twWj3M5ECBrrTq6ci20o+qqWcQMAEpXzPbEoJQ5jtFl06XypNTVE/RqgtPVI23Z5WvxfC4ggFLiW6vjrd6ok5ZtmRb99B++p0zLKUnSmbZWZVpP64/u/RPNX7joose/tvkF/ern/6ia2jqdaWtVTW2d7v/jb43odZ/874+M+M+fb3yNK2stlSIAgNDzfKt50xztOhSvXUmHTlpt3etx0xII0PNbPPVEdL/VhJQ0vpZjC4DSRVIEJSU/cP2tPdHdLTEUr+zw9cEF9OsHSoljjA6NskqkLdOiv3t6jb5070OqTdX3fv3Fn/+jvvaFD2vNUz/R4ptu6f3633/vO3pt0wv6y6d/2udrf/7HX9Z/+c4PhvSaT3znz3TowF4tuPoGvb75l7rxpk+M6meQpMl1HJ8AANHgGOny6UY/fz3olYy9X7zhaSGV+sCY861V5qz0+rvRve9x5UxHvrVy2EQFoERxBYSS4vlWjXP4tTzaYtW8jz6/QKnwrVXLWU+Z9tEFLi9uXKuf/MMzams93efrH//UnapJ1evJ//5I79fe2bZFT3znEf3Jn/+PPo/94lf+WK+//Eu9+PN/HNJr3v/H39J/+c4P9MWv/LFqUnWjWr8kVZYZVZUzTwQAEA3GGE0db1SeDHolY+9kRnr9HV8+MQcwphxj9PPXPXnRzYnoqgbu6wAobRylUFJylSLxG3bYn+feyIp7jkBpcIzR7qOj7+s3beYcSdKZtpZLPvb/PP2Xmr/wek1vmHvR9z6xbIV+8sO/GfV6RmJSKtc6CwCAqHCM0Zwp8bzwfuF3nsiJAGPH962OnPb1doS7Y5QnpdlTDFUiAEoaSRGUnIRrdMUMTp7HW6U33qVaBAhabpZIVm0dow9cFt90i3666WC/s0POZFp0ZeMNvf//9Zd/qWkzL06ISNL8hYv0+su/HPV6RmJSHVlrAEC0eL7VZdPjGRq3dUibtlEtAowVxzHa+JqnKH/iLp9u5DCrCECJi+eVH0qa51tdTQstSdIvf+cp0ldLQAgYSXuOjb5KZDB//73vSMq1xso7k2kZ8PG1deMk5VpsjaWKpFFNBa2zAADR4jpGjTGerfHrt6M77BkoJZ5vtfeIr3cPRjvIX9DgsLkTQMmL75UfSpbrGC1ocJRgjq9a26VN29m5BQTFt1ZHWjx1dBfvM9iWadFPfvg9/efv/KBPq6ya8waxD+TQgb1FW1d/JtI6CwAQUXXVRg2T4pn07+yWfvmWxzkeKDLXMdrwmhf0MorKmFxSxKVSBECJowcGSlJZIjdbpHkfF+a/fsvTB650VE4KExh7VtpbhCqRtkyLfvoP39Oh9B5lWk9rzVM/uWh2yJULFw1YLXL4wJ6Cr2koJteRrQYARJPnW107z1H6eLRvWA7kt9t9fbjRVVWFZQ4AUASeb7UzbXXgRLTvccyYaFRZzjEEQOnjNitKku9bLZ7PzTdJ6ujOJUbYuQWMLWutDp7Kqjtb+M9ebapeX/zKH+tP/vx/6DOf/4r+8r98Uy/+/B/7POaLX/3jAeeG7Nj6hiSprfV0wdc2kLKEUW2lS+ssAEAkuY7RdfMcxXVzc48nPfeGR0IEKBLHSL94I/p96hbMpHUWgHAgKYKS5DhGl003qq0KeiWlYdN2X+1duVY+AMaG50v7TxR3loiUG77+n7/zA/3nP/6yfvKj7/X5+mc+/xU98Z0/6/P4F3/+j1p80y2S3p8tMhYm0ToLABBxVeVG86bFNynwxi5fx1po3QsUmu9bvfqOr+OtQa+k+K6aZWKbXAYQLiRFULqstOgyfkUlqScrPbfFE9cWwNiw1mr/iR5lx6iDRm2qXh/71J36y//yTbWd1zLrT/78f2h6wzz95Eff6/1n/lXX9yZDamrrxmaByiVFAACIMs+3um5efOMP30r/8BtPBB1A4fi+1ZlOaWPEZ4lIUl2VNGWcQ2U5gFCI7xUfSp4x0uIruAmX9/o7vlrOiJ1bQJFZa9XjSQdPjm15+4Krb5Cki1pmfebzX+nzz/SGub1ts65svGFM1pZ0pVQVAQ4AINpcx6hxjqNEjEOQQyetfvO2T3UoUCCOY7T2X7PqKn4BeuAa5zh0twAQGiRFULKMMRqfMmqYxE04Kbdza+PrnhxqUYGiMsZo77EeFSP/+OmlM/Tnf/zlfr9XU1svaWhD1N/ZtkXzF16v2lR9AVc3sImpxJi8DgAAQStLGF05M97X2y/8ztOJVstmLGCUfN/qtXc87ToUj8/SB650KTQDEBokRVDSPN/qhsv5Nc3butfXOwd8BpcBReJbq9Z2T4dPF75KpC3TojPntca60KH0bknStJlzL/lcv9y4Vp/5/FcLtbRLmlIf4y2zAIBY8Xyr6y+L93nP86Uf0UYLGJV826z1r0a/bZYkzZpsNLHOUFkOIDS424yS5jpG181zlIx3XNLHP27KKusxdB0oCivtPNhdlKeuTdXrM5//iv7Ld37Q7/dff/mXqknV6+OfulNSbqD6p5fOuOhxL/78H5VKjdNnPv+VoqzzQpVlRnVVLgEOACAWXMdo/kyjirKgVxIs2mgBoxOntlmStPgKh82bAEKFpAhKXjIhXRvjgYcXamuXfvZbTw43KIGC232sRx3dxbuY/+JX/viiYeqS9JMffU/vbPudvvP0T3u/1tZ6WlcuXNTnce9s26Inv/OI1jz1k4ue+8//+Mv60vKrB339M5lWZc7NIxmqaeMSJGEBALHiGKlxNvEHbbSAkYlb26zyZO6ejUurbwAhQpNwlDwr6eZGR6+/6we9lJLxxi5fV8/xddl0w4UHUAC+tWrr8Is+XH16w1z9yZ//Dz3xnT+TJJ1pyyUpUnXj9JNNB/vMCPnM57+iM20teuI7f9b7uOkz5+iJH/7rgLNEalJ1F33t77/3He3Y+oYOH9ijQ+f++ZN7P62aVL0+sfxzvZUp/TEmlxQhCQsAiBNrpevnEX/k22j9+09z2wAYqri1zZKk6+Y5cskjAwgZY6mHRUh8b0OPdh/h1zWvtkr6f92ZVDIhblgCo+T7Vq+911nUKpEwmpRytbChPOhlAAAw5qy1+vYPe9TWEfRKgvfJG1x99BqHVprAEH3/5z2xqRKRpG98NqEp4wz3JQCECrlchILnWy1tZLDI+WijBRROsdtmhdX08Ql6iQMAYslKumYu4bJEGy1gqOLWNkuSpo03mjbe4b4EgNDhKg+h4DpGV840Gl8b9EpKyxu7fL1zwGegGTBCvrVqbfeK3jYrjCrLjOqrGbAOAIgnI+nGKwiXpffbaEliswQwAM+3OtMRr7ZZkrR4PgPWAYQTV3kIDd9KH1xAtciF/nFTVllPDEIGRsJKOw92B72KkjR9PAPWAQDxZYzRlHGO5k5lc4AkHTpp9S8ve2yWAPrhWytrpf/9fFZdPUGvZuwkE9KiyxiwDiCcSIogNFzHaMl8R+XJoFdSWmijBYwcbbP65zoMWAcAwPOtPnI1m7LyXnvH18vbPapFgAs4xuhHv87q8Kl4fTaunuMomQh6FQAwMiRFECrJhLTocn5tL0QbLWB4aJs1uCn1CbHhCwAQd65jNH+mo0l1Qa+kdKx7xdPeo5a4AzjHWqtf/s5T8774fSY+cKUjcqQAwoq7ywidj17tyuU39yJrX8qqo0sMQAQuwVor35d2HKBt1kBmTmDLFwAAUq5a5OZGqkXyfCv93S+zamsXiRHEnu9b7UhbvfC7eM0RkaRJdVLDJEcOO6kAhBS3lhEqxhilqo2uv4xf3Qud6ZD+93NZWcsAROBSmvd3qbOHz0l/xlU7qixz6BkOAIBy1SKLLndUUxn0SkpHR5f0v57LyvOZa4j48nyrExmrH/06qzh+ChbPd0mMAgg17iwjdKy1+sR1Lq1d+nHwpNXalxiACAxm1+EetbT7QS+jZM2ckCSxCgDAeYykDy6gWuR8x1qsfvirLPPHEEu+b9Xdk9uU2B3DbrzJhHTDFQxYBxBuJEUQOsYY1dcYXUe1SL/e3O3r128zABG4kLVWh0716NDpGEYuQ1RdbjS+1iWxCgDAeRzH6KarGCh8oR1pq+fe4LoK8fR3v8zq9JmgVxGMD1zpqCIZ9CoAYHS4q4xQ8q3VLVSLDOgXb3h656Blvghwjm+tMu2+dh3pCXopJW3O5CRtMAAA6Ed5UlrEpqyLvPiWr617PeIOxMpPf+tpz5F4/s4nXelj11A5ByD8uKpDKDnGaFyt0bVz+RXuj7XSD3+V1akzDEAErLXqyVo1p7vE/f6B1VQYTUwlaIMBAEA/rKSPXOOK0+TFfvyvno61WOIORJ61Vq/s9PTKzvi24l1ypaPKclFZDiD0uKOM0PKt1S3XE5gMpKtH+t+/6FE2K3ZuIbastfKt9Pa+LvV4Qa+mtFElAgDAwBxjNK7G6KoGgo8L9WRzsxXOdLAhC9Hl+1bvHbL62W/jG1QkXelj11IlAiAaSIogtBxjND5FtchgTrblep2SOEJcGWO040C3znYRoA+mpsLRhFqqRAAAGIzvW32EtjH9am2X/mZDj9o7SYwgenzfat8xqx+8kJUX3yIRLbnSURVVIgAigrvJCDXfWn3yBlcuv8kDeu+w1bpX4rubBfG291i3TrTx+38pc6kSAQDgkhzHqGGSo4ZJ3BDsz6m2XGKks5vECKLD960OnLD6X89llY1xWJGgSgRAxHArGaHmGKO6aumDC/hVHszm7b5ef8fjpidiw1qr461Z7TueDXopJa+20tH4WpcqEQAAhsDzrT58NTcGB3IiI/3Nhqy6e0iMIPw83+rwKau//UVWPTEPK5bMp0oEQLRwJxmRcOv1rirLgl5FafvnzZ52pi2JEUSetVYtZ31tP9gd9FJCgVkiAAAMnesYLZxlNDEV9EpK17EWq7/ZmLuJTGIEYeX5VsdbrJ75eVZdPUGvJlgJV/r4dSSDAUQLSRGEnjFGyQSlnJfiW+nZF7PaddAyeB2RZa1Vpt3X1v1d4j7/paUqHY2voUoEAIDh8K30yRsTQS+jpB05ZfU0FSMIKd+3OnI69zvcyT4rLaZKBEAEkRRBJDiO0U0LHY2rCXolpc3zc4PX9xwlMYLosdaqrcPX2/u7xK/30MyZQpUIAADD5TpGjbMdzWS2yKCOnLJ6an2WGSMIlfwMke+REJF0rkqEDagAIoikCCLlUzdysr6UrCf94Pms0sdJjCA6fGt1ttPXW/u65PlBryYc6qocjaumSgQAgJHwfKvblxB7XMqxFqsn1/WovZPECEqf71vtO2b1fVpm9brxCkfVFVSJAIgekiKIDNcxumauy46tIejJSn/7i6wOnCAxgvCz1qq9y+pNEiLDMmdyUpYqEQAARsR1jGZPdnTlTGKPSzmZkZ5c16MzHSRGULp8a/Xe4dxQ9e6YD1XPS7jSJ5glAiCiSIogUjzf6tMfdEVocmndWen7P89q3zESIwgva63OdPp6c0+nsl7QqwmPcdWO6qtddnwBADAKvm+1fIkrh9PpJZ0+I/3Pn/boyClL606UpC3v+vrB81liivNQJQIgykiKIFJcx2jmREeL5/OrPRTd5ypGdh8mOEH4WGuV6fD15t4uZakQGTJjpCuml1ElAgDAKDmO0aQ6R4suJ/YYirYO6an1Wb21mws3lAbfz8XBP/1tVv+4yaPq/DxlCapEAEQbV2+IHGutli92VV0R9ErCIetJ//v5rN45QGIE4WGtVWs7M0RGomFCQhVJw44vAAAKwLdWn7zBVVki6JWEQ9aT/uE3nta/mpW1xB8Ijufb3CbBn2f18nYCigt9/DpXVVSJAIgwkiKIHGOMEgnpDgYfDpnnS3//y6y27fPZPY6SZ63V6bO+3t7XJZ/4ZVgqkkazJyUJbgAAKBDHGFVVSB+9hthjOF5q9vW/n8uqJ8ucEYw937c63Sb99U969N5hfv8uNCEl3dzoyCFmABBhJEUQSa5jdN1lruZN4yQ+VJ4vNb3o6Vdv5e4ys2sLpSafsDt4KptLiPArOmyXT0uKoUsAABSWY4w+crWjcTVBryRc3jlo9dc/7VHrWTHjEGPGWqt3D+V+9062Bb2a0vTpD1L6BiD6SIogsnzf6g+WJpRg09aQWUnPbfH07ItZ+T67tlA6rLWyknYe7NJ7R3qCXk4oTah1NaE2wY4vAACKwUi3L+FG4nCdaJX+6ic92n3YUrGOospv+vv127mB6l2EFP26cqbRFTMcuQ4xA4BoIymCyHIco/oa6SNX82s+XFv3+npyXVbtnSRGEDzfWmU96c29XTrS4gW9nFByjHTFtCQ3GwAAKBLXMVo429G8qdxIHK7Obul/PZfVS825inWuV1Bovm/l+9IPf5XVL97wxK9Y/xKu9JkPJajcAhAL3C1GpDnG6OPXuZqYCnol4XPopNV3f9KjQycZgIjgWGvV3mX1+u5OZdoZIDJSsyYlVZZguDoAAMXk+1af/pArNlgPn2+lDa95+vFvsvItG7NQOL5v1d4lPbUuq7f2EE8M5sONjuqqcxtMASDqSIogFv7wowmCkxE40yE9vT6rLbu4eEQwjmc8bdndqa4eAuORqiwzapiYICECAECROY7RpDqjJVcSZo/Ulvd8ffdfsjp6mnZaGJ38xr639/p67J96dPAkv0+DGV8rffw6l5gBQGwYy5UGYsBaq+e2vD9EHMN301WO7viAK2vZOYListbKGKM9R7u1/0Q26OWE3rWzy1VX7TBLBACAMWCtVU9WeuyfcgPEMTKOkT58taNbF+UGRDLfAMPh+1Yd3dI/bcpq+35ueQ3FPcsSmjPF8FkDEBskRRAbvm/11z/N6vApfuVH6vLpRl/8eEKJBIEJisO3VtZK2w9062Qb80NGa1LK1cKG8qCXAQBArHi+1b6jVs9szIrIY3Qm1xv94UdcTRtPG1Bcmm+tHGP05m5PP/2tp46uoFcUDtfNc/T5jyaCXgYAjCmSIogNz7c6lbH67k+yynKvdcQm1EpfvjWhCXWGnecoKGutunqstu7v0tkuTk2j5TrSB66oVNIVNxEAAAjAT17O6rc7qFQfLapGMBRUh4xMVbn0f69IqrxMxPcAYoWkCGLFt1YvNfva+BpZkdFIuNIt17v6yNWOfEtggtHJt8s6cLJHe472iLmahXHFtKSmjWOWCAAAQbDWyvOl//FPPTrZFvRqooGqEfSH6pDRWfFhV9fPc2iRDSB2SIogdqy1+psNWe09yq/+aM2caPSHH0lofIpdJRiZfHXIjoPdam1nJ2WhTKh1dfUs2mYBABAkz7c6dNLqyXVZEXUXBlUjOB/VIaMzb6rRV5Yng14GAASCpAhix/et2jqkx/+pR109Qa8m/KgawUhQHVI8ZQmjJZdXyHVomwUAQNCstfr5655+s5XNH4U0ud5oxYddzZzoyPctu9xjxvOtXMfod+95+tkrVIeMRFlC+ubvJ1VXLT4/AGKJpAhiyfetmvf5avoVbbQKhaoRDBXVIcV17exy1VU7fA4BACgRnm/1V/+S1dEWQu9Ca5xttOzGhManTG8bJURXPgH23uFcS+xDJ/lMjdTnPuzqOtpmAYgxkiKINYYfFhZVIxhMvjrk4Mke7aY6pChmTkho3pQkFSIAAJQQz7c63mr11z/JyiP0KDjHSDdc7ui2G1xVV1ApG0X5ZMjhk742vObpvcMEEqNx/WWO/vAjiaCXAQCBIimC2LLWyrfSkz/L6iA7TAqKqhFciOqQ4qupMFo0r4LPHAAAJchaqxff8vX8FirViyXpSh+6ytHHr3WVTNASKAp8a2UknT4jbXwtq237rIjcR2diSvrGZ5NKuCQQAcQbSRHEWn6+yP/vn3vU0R30aqIl4UqfuM7Vh692JFE1Elf5QObgqSyzQ4rIcaTFl1WoImkIbgAAKFG+tXriZ1kdPMEFUTFVlEkfvcbV0oWOjCEOCSvfWrV3Ss9t8fTGuz5xRAEkXOk/fDqhiXWGzwWA2CMpgtjzfat3D1r94Pksu06KoL5aumWRq0WX0VIrTvI9nY+1ZrX3WI86uvl0FdP86WWaWu+SEAEAoIT5vtXpM9L/+OceZSkYKbraKumW61zdON+RJQ4JDd+36vGkX73lafM2Xz18Vgrm0x909YEFzB4EAImkCNBr42tZ/WYrbX2KZXK90adudLWgwZHnW4KSiMonQ06f8bT7aLfOdHKKKbaJKVeNDeVBLwMAAAyBb602b/O1/lXu9I6ViSnp49e6umZernLEiLZBpSY/M6Sjy+q3O3y91OzRyaHArppl9Ee3JINeBgCUDJIiwDm+tfrehqz2HuUjUUwNk4yWL3Y1e4rTe/GL8MsPUW/r8LT7aI9azpJgHAvlCaPFl1fIdQjuAQAIC2utvrcxqz1HiDvGUlW5dMMVjm66ylVdtWGjVgnI/x2kj/t6ebuv5n0+VVRFUF8tffP3kypLEjMAQB5JEeAc37fq6pH+6ic9On0m6NVE3/yZueTI5Hqnt7oA4ZNPhnR0+9p9tEcnMkQxY+n6OeWqraIEHgCAMMnHHd/9lx61nA16NfFjjHTFdKMPXuVq/gwjaxnKPpbyMweznvS793y9stPX4VPclioWx0j33ZHQ9AnMEQGA85EUAc7j+Van2qz+50+z6uoJejXRZ4x07VxHn7rRVapKshI3d0Mif+ro8aQ9x7p15DTJkLE2e1JSsycl2O0FAEAIeb7ViVar//mzrHqyQa8mvsbVSEuudLVkvqPKckMlexHlq0JOZqw2b/f0u/d8ddIiq+g+eYOrj17jEDMAwAVIigAX8H2r9w5b/e/nsvL5dIwJ15EWz3f04UZX42opZS9l+aqerh5fB05mdegUn5MgTEq5WsgcEQAAQs33rbbt9/Xsi2wuCVrClRpnO/rQVY4aJuXa/BpDq6HRyr+PVtL2fVa/3eFpN23jxsxl04zu/hSbqACgPyRFgH5Ya/Xydl8/e4UAZSwZSZdNN/rgAldXNuSuntmpVRryp4rTZ3wdPNWjU2eYGRKU2kpH188pJ1AHACAinnsjqxff4tqqVEwZZ7RwltHC2Y6mjXdkraXF1jDkN7h5vtXeI1bb9/tq3u+rrT3olcVLTaX0wO8nVVHG7y4A9IekCDCIf9mc1Ss7CVCCUFctLZnv6gNXOqqqoJQ9CPl5IVnP6vDpXFVIZw+njCCVJ4xuvKxCCZeECAAAUfKD53u0I811Vqmpq5KubHB01SxH86aZ3pv9VLX3lX9POrutdqR97UhbvXvQpyV1QIyR7v5UQnOmMEcEAAZCUgQYhG+t/vbnWb13mI9JUFxHWjjb0YcWOJo9xSEIGQP5FlltHZ4OnszqeMajRVYJcBzphrkVqiw3zN4BACBCrLXq8aT/+dOsjrVw0VWqyhLS5TOMFpxLklSWxTdB4lvbW9V/+oxV815fO9K+9h+zxA0l4Pc+4OpDVzFHBAAGQ1IEGITv5wKUJ35GgFIKptQbfWCBo0WXO0q6km8VyyCkGPKnAmulo62eDp3q0ZlOfudLSWNDmSbUugQ3AABEkOdbtbVL3/1Jjzq6gl4NLsUYadakXILkygajiSkjxzGy1kYuRrHWyvOlhJv7mXqyVodOWe3Yn0uEHG8NeIHo4+ZGR7cvSQS9DAAoeSRFgEvwfKv2LumJn/ao5WzQq4EklSdz1SMLGhzNn2GUTMR3l9Zo5CtCfN/q9FlPJ9o8nWj1lKVjXMmZOyWphgkMSQQAIMp832rvUavv/zzLbvuQSbjS1PFGMyYYTZ9g1DApnIkSa618X3LPS4AcOW114LjVoZNWB09aHW/NzVhB6bl6jqO7Pk5CBACGgqQIMASeb9VyRnriZz1qZ+dWSUm40typuV1ajbMd1VTmbvIzhPpi1lpZSY4x6slanWjzdDLj6fRZ2mOVsin1rhbMKA96GQAAYAxYa/Xydl8/e8ULeikYpcESJdL7CQgZyRnD2MW3Vvbc656fqMknQNLnEiCHSICEypwpRvcsS4zp7xIAhBlJEWCIPN/q6Gmrp9dn1Z0NejUYyLTxRlfNcrRwltHU8U4uEXCu320c5Q/xxhi1d/k6nvF0ss1TWwflIGFQV+Xo2jnlMiK4AQAgTv7xpaxef5frtahJuNKkOqNUlVRbZVRbKaWqjGqrjOqqpdpKo6ryvrFLfmOTzt256b2Bk/8P0+df55Isfa8bs57V2U4p027VelZqa7dq67Bq68j9d+tZqxMZkQAJqUl10r//vaSSifjGvQAwXCRFgGHwfat9x6z+9hdZZdm8VfLqqqQrzw1CnDvV9PbBzXpWrhPNm8y+tb030H3fKtPh68S5REhnD4f7MKlIGt14WUVkf1cBAED/8u2W/mZDVvuPcf0WN8ZI1RW5BEltVe7fCVdynFxFidv7byOrXIzq+bl5i74veb7Unc0nPnL/7ugO+qdCsdRUSl//dFLVleFo0QYApYKkCDBMvm/17kGr//MCvX7DxJjcrqx8+frMSUZTx+XmkUiS51k5Ibv5fGEC5GyXr0yHrzMdvto6fLV3WfErGk6uI90wr0IVZeainX4AACD6fN+qs1v665/26PSZoFcDoBSVJaSv3ZHQpHpDQgQAhomkCDAC1lq9vdfXj37tUWIcYpdKlPh+fihicMmSfPuv82ekkACJNteRrp1drtpKJ1RJOgAAUFieb3WmQ3ryZz1qbQ96NQBKiWOkf3NbQpdNM7TMAoARICkCjJC1Vm/t9vXjf2VIdZTkEyWT68/1+q00urnRKdiFpu/bXMNf+/7rXXjj2/OturNWXT25f7qz7///9i4SIFHmGOnaOeVKkRABAADKXRdmzkpPrutRW0fQqwFQKu682dUNlxMzAMBIkRQBRsFaq63nKkZIjESTY6RH/11ZQZ7Lt1ZHTnuyylV/+Fa5hMe5xEfXuf/mdymeHCNdM7tcdVUENwAA4H2eb9VyJpcYOdsZ9GoABO0T1zm6dVEi6GUAQKhxFAVGwRijq+c4ch2jpl9l5flBrwiFVpYs3HN5nvTuYaYc4mLGSFfPIiECAAAu5jpG9TVWX12e0NPrs2rvCnpFAIKy6HISIgBQCE7QCwDCzhijBbOMvvSJhFw+UZFTXsDrTY8SEPTDGOnqhnLVV5MQAQAA/XMdowkpo68sT6iiMEXMAEJmQYPRnUtd0fAFAEaPW7hAATjG6IqZRl++NaGEG/RqUEiFrBTJUkmECxgjNTaUaVwNCREAADA41zGaXGd0z7KEygt4jQqg9F0z19GXPpHodyYlAGD4SIoABeIYo8umGf2b2xJKkhiJjLJk4S44PY8dPXifkbRwZpnG17gENgAAYEgcx2jaOKO7P5VQGR10gFi44XJHX/ioS0IEAAqIpAhQQI5jNHdKrqy9sjzo1aAQCrkLj0oRnO+qmWWaUEtCBAAADI/jGM2YYPRvP8lmLCDqPrjA0YoP5zKgxA0AUDgkRYACcxyj6ROM/v3vJTWuJujVYLQKtQPPWstMEfRaMKNME1MkRAAAwMg4jtGsSUZfvo32vUBUfeRqR5/5EAkRACgGkiJAEbiOUX2N9O8/ndS08Vy8hFl5gdpnWUkelSKQdOX0Mk2uIyECAABGJ1+l/kefSMglsgci5dZFrpYtpkceABQLl05AkbiOUWWZdN8dCV0+nZufYVWezFV5jJplpkjcOUa6elaZptSTEAEAAIXhOEaXzTD64ieoGAGi4vYlrj5xHR9oACgmkiJAETmOUcKV/u1tCS26nI9bGJUlpIJ0vTLMFImzpCtdP7ecoeoAAKDgHGM0f6bRPZ9KqKIs6NUAGCkj6fdvcnVzIwkRACg27tICReYYI2Okz304oY9fy0cubMqTJtf7apSMxEyRmKosM7phXoWqKxwSIgAAoCgcY9Qwyej+OxKqqwp6NQCGyzHS5z7iavF87hkAwFigQSEwBvI3Qm+7IaHJ9Z7+8SVPPV7Ai8KQlCUL91zMFImfVJWja2aVy3UYjggAAIrLcYzGp6R//5mkvr8xq6Mt4dyQs/3VtdrT/Fyfr93yhf+miqr6UT12qDavW6OpsxdpbuOtI34OYDhcR/rCxxJaOMsQMwDAGDG2IM3yAQyV71sda7X6wfNZtZwJejW4lD9Y6mrR5Y5cZ/QXp9sPdOlYK9mwuJiUcrVgZpmMSIgAAICx4/lWWU/6wfNZ7TkSrnD/hR/+qeY23tonIXH62G6t/asv6Y/+44Y+yY7hPHaoOttb9JffmKIVX/97XbVkxWh+FGBIEq70pU8kdPkMI4eYAQDGDHV5wBhzHKNJdUbf+ExS86Zx0VPqypK51leFQKVIfMyckNDChnISIgAAYMy5jlHSle7+VELXzA1PyH947xZJuqhCY9zkebrj7r/Wz575DyN67HBsefHpEf05YCRqKqV7lyd0+XQSIgAw1sJzhQREiOsYlSdzgcrShXwMS1lF0sgpQJWIxEyRuLh8alKXTc1NOSUhAgAAguA4Ro6RVn4sPHMN9257XtPmLu73e9PmLNKRfVtG9Nih2tP8vOYspGUWxsa08bmNktMmFC7eBAAMXTiujoAIygUqRnd8IKHPf8RVwg16RehPRVnhnsujc1akOUa6elaZpo9nXBcAAAje+XMNv/DRcMQbW158qt+vnz62W+MmzR3xY4fiyL4tmjZn0bD/HDBcjbON7v+9hKorVJA2zQCA4SMpApSAa+Y6+ve/l9CEVNArwYXKCzponUqRqEq60vVzyzW+xqU6BAAAlJyr5zi69/aEaiqDXsnAFixeoT3bXtCPv/tFdba39Pne5nVrdNMdD43osUPxxotPD/vPAMNlJN1yvasvfiIpxxEVIgAQIJIiQAlwHKNJ9Ub/12eTWnQZH8tSUp4s3IVqlpkikVRX5Wjx5ZWqrnBIiAAAgJLkOEbTxht9/TNJTR1Xmtcr4ybP0y2f/6/a8dpafffhK7Wn+XlJuYTF3Mbb+swPGc5jL+X0sd2qrB5f2B8GuEAyIX3xEwndcn2uZIsZIgAQLGOtZesyUCKstTLG6M3dnv5ls6eunqBXhD+9K6mqisJcsP7r9naGrUfMrIkJzZmcKyciIQIAAEqd71t5vvTDX2e1fX9p3grY/uparf2rL0qS6ifN1ZceWqdxk+eN+rEDubCy5L/eU64VX/97XbVkxQh/AqCvCSnpj25JaGKK+SEAUCrYkg6UkPxN1WvmOPrm7yc1YyIXTEFLFnA8BAmR6Ei60rWzyzVnclLGGBIiAAAgFBzHKOFKf3RLUp/+YGnOGamoqtNNt/+J5i68RS3H9+jv1tyhw3v7H5w+nMf2Z/ura7VgMckPFM9Vs3ID1SeQEAGAkkJSBChBjmOUqpLuvyOhj1ztiEunYBhJyURh3n2feSKRUX+uXVZdNe2yAABA+OSvXz6wwNHXP5PQ5PrSuZ554Yd/qs72Vt3yhf+mLz28Xrf/u++q5fgefe+/fKi3RdZIHtufzvYWdZw9NezKEmAoHCN96kZXf3RLUskEA9UBoNSQFAFKlOPkdpJ86kZX9yxLqL466BXFT1lBh6wX7rkQnNmTErp2TrmSLn2AAQBAuDnGaELK6OufSWjJlcHfGnjjxaclqU/bqhs+fq++/v9sV/2kuVr7V1/qHao+nMcOZMuLT+uGj99b2B8CkFRdId2zLLfBUaLNLgCUouCvfAAMyhij2VOMHrgzqQ9cSdXIWCoraOssKkXCLJmQrptTrtmTaJcFAACiw3WMXEf6/ZsS+qNbEqosD24tm9et0S1f+G8XfX3c5Hn66n9+WZK0p/mFYT+2P4f3btHU2YsKsWygj9mTjf6v309q1mRiBgAoZQW85QegWFzHyDFWn70poevm+frxv2Z1qi3oVUVfOZUikFRf7WjhzHK5Lru8AABA9OSvb66cafTAHyT1w19ltefI2G7o6WxvUUVV/YDfr6iq19Lfe1gtx3cP67EDaTm+R9te+VFvxUle17nqkk0/+7a2vfIjVVaP0x13/9VwfhTEVMKVblvk6uZGR9aK+SEAUOJIigAhkQ9WZk7KBSu/eMPTpm2+LAUIRVOWLNyFbJZKkVCaPSmp2ZNyp0oSIgAAIMocx6i63OoryxL61Vu+Xvidp7G6hK2oqr9kuytJqp80b1iPHchVS1b0ab2V19neor/8xhQt/b3/2O/3gf40TDL6/EcSqq/VuaryoFcEALgU2mcBIeM6RgnXaPliV/f/XkKT6oJeUXQVslIk6xXuuVB8lWVG188t1+xJCdplAQCA2HCc3HXPx6519LU7EhpXM3avPW7S3EEHpO9pfl5zG28Z9mOBYkm40vLFrr52R0L1NcwcBIAwISkChJQxRtPG5/qV3rbIVZK6r4Ir1EwRay0zRUKkYUJCiy+rUG2lQzIEAADEkjFG0yYYffP3k7p27tjcNljxjb/XCz/6TxclOzrbW7Tu+1/XTXc81Ns2aziPlaQff/eL+u5/XHDJNZw+tkeS1HH21Oh+GERewySjB34/qaWNuZiBdlkAEC7GWprvAGHnW6uzndK6Vzy9vYfhFYVy7VxHX/jY6DMjvrU62uLpnUPdBVgViqW63OjKGWWqqSAZAgAAIOU29xhjtGWXp5+94qlzDC5nX/jhn17UHuuWL/y3fueIDPWxP/7uF9VyfE/vEPYLHd67RZt+9m21HN+jI/u2qKKqXnMW3qK5jbfqho/fO4qfBlGTcKVbF7n6MLNDACDUSIoAEeFbK8cY7Tvq619e9nT0NB/t0Voy39Fnb3JHfYPc960Onc7qvSM9BVoZCskYadbE3OwQK8reAQAALuT7Vp3d0vpXPf3uPV9EGoijhklGf/iRhMbVEjMAQNiRFAEixvOtHCP9doev57d46qA4YcRubnS07EZ31Lt/fGuVPpHV3mMkRUpNXZWj+dPLVFnG3BAAAIDB5DdhpY/7+ufNno6c4lYC4oHqEACIHpIiQET5vlVXj/SLNzy99o4vRloM3y3Xu/rYNY5cd/RJkb3HepQ+kS3QyjBaSVeaN7VMU+sTvW0hAAAAcGnnb8J6bsvYtNQCgjJzktHnqQ4BgMghKQJEWP7j3Xo2lxx5azel7sOxfLGrD13lKDHKpIi1VrsO9+jQaZIipWDaOFfzppTJdUQyBAAAYIR836qzR9rwqqctu4gzEC3VFdInrnP1wQVUhwBAFJEUAWIgX+p+rMXXz1/3tCPNx34ofv8mVzdcPvpKEUnacaBLR1u9AqwKI1VTYXTFtDKlqlyqQwAAAAogf0114FxLrcO01ELIJd1cG+WPXusq4ZAMAYCoIikCxIjvWzlOrg/wz1/3tOcIH//BfP6jrq6Z4xTkQnjr/i6dbCMpEoTKMqO5k5OaVJfoTRACAACgcPIttV7Z6eu5N5hriPAxRrrhckefvMFVdQUV5QAQdSRFgBjKJ0feO5TrA5w+zmGgP1++NaEFDU5BnuvNvZ1qOesX5LkwNGUJozmTk5pa78qKHsAAAADFlp9ruPE1T6+/S0sthMP8GUa3L3E1qd5hExUAxARJESDGPN/KdYz2H/P14lue3jnA4eB8996e0JwphUmKvLG7U20dJEXGQsKVZk1MasaEhIzY5QUAADCW8i21Dp309bPfetp3jBgDpWnaeKM7lriaO83p3TgIAIgHkiIAei8Aj7X4+vVbvt7a48vnyKBvfDahaeMLkxR5dVeH2rt4U4vJcaSZ4xOaNSkpx5AMAQAACFJ+A9beI75e+J2n3bTuRYmor5E+ucjVdZe5vb+nAIB4ISkCoFc+OZI5a/XrrbmS955s0KsKzh9/LqnxtYW5QH75nQ519XC4LQZjpGnjEpozKamESzIEAACglJw/1/CXv/P0zkGuiRGMijLpY9e6Wrowt/GNZAgAxBdJEQAXyR8WunpywxJf3enp9JmAFxWA/89dSVVXFOZC+aXt7crSPavgJte5mjs5qfJk7u+JhAgAAEBpyidHDp/KVY7s2G+ZOYIxUZaQllzp6BPXuSpLiDZZAACSIgAGlw9edh309fKO3NyRuLTWWvXlpMoShblg/nVzO0FfgThGmlKf0MwJCVWVO719qwEAAFD6zm/d+8s3fW3d64u7EiiG+hrpQwtcfeBKR8lE7mvEDQAAiaQIgCHKBy9t7Vav7PT02ju+2jqCXlVx/cW/Sxbkotm3Vr/ZFvE3awyUJ4ymj09o+viE3HOjXghqAAAAwikfX5zKWP3yTU9v7mauIQqjYZLRzY2uFs42kqUyBABwMZIiAIbNPxetbE9bvfGup12HrLyItYYqS0irvlxWkOfq8aw27SApMlKpSkczJiQ0KeVKIhECAAAQJb61coxRyxmrF9/ytGWXH7nYAsXnGKlxjqMPNzqaMdFhgDoAYFAkRQCMWP5Cs7Pb6s3dvt7a7Wv/sWj0Bq6plP7fKwuTFOnq8fXyO50Fea64MEaalHI1c0JCtZVub7AMAACAaPKtlZF0plPavM3T6+/6OsslNC6hokxaPN/RzQtd1VaZ3gokAAAGQ1IEQEHkEySZdqstu3IJkqMt4T28TKiV/u/PFSYpcrbL12u7iOiGIulK08YlNGNCbp4L80IAAADixdpzm6ystG2/1as7Pe0+HI2NVyicCSnppqtc3XiFI9eVjKgoBwAMHUkRAAWXT5Aca/H19h5fO9JWh0+F61AzbbzRNz6bLMhzZdo9bdnTVZDniqraSkfTxiU0pd5VPpQhqAEAAIi3fFzRciY31/CNXb7O0JU2toykuVNz80LmzzTyrWiRBQAYEZIiAIrGWit7brBdW7vVtv2+dqZ97T5ilfWCXt3g5kwxuvf2wiRFTp3x9PY+kiIXqi43mlyX0OQ6VxVlDi2yAAAA0K/zq0d2HrB6Y5endw5Eb64h+jepTrr+MlfXX+aortowLwQAMGokRQCMmfzFa0/Watchqx1pX+8c8NVWgru95s80+re3jT4pYq3ViYynbQe6C7Cq8KtIGk2uczWlPqGqcof2WAAAABiWC+cabnnP14Hj3NaImtpK6dp5jhZd7mjqOAanAwAKi6QIgED4vpUxuRZJpzJW7x32teeI1Z4jpZEkuWauo5UfS4z6eXxrdazF085D8U2KlCWMJqVcTal3VVvpKn/aIRkCAACA0cjfKD/VZvXGu57e3O3r9JmgV4WRqiqXFs5ydO08R3OnGlkxKwQAUBwkRQCUhPN3/pxqs9p9XpIk0z7261l8haM/uLkASRHf6vDprHYd6SnAqsIj4UoTU66m1CVUV+X0fp2ABgAAAIV2ftvekxmr7ft9vXvQ196jtNgqdbVVuUTINXMczZpiZKTev0sAAIqFpAiAknR+kuRMh9XBE1YHT1odPOHr0CmrtiInSpYudLR8sTvqi3HfWh04kdWeY9FPitRWOKqvcTSu2lVdtcPAdAAAAATi/La97x222nnA17sHfLWcDXplkKTxtdKCBkfXzHXUMMnpk9QCAGAsjH4bNAAUwfn9Ymsqja6YIV0+w8h1XElSe6fVgXOJksOnfJ1ozVWYFGqAe3lSKlTGOOtHM/dcWWY0rsbVuGpH9dWuEq6hNRYAAAACl48lkgmj+TOkK2e6MiahE625uYZUkYytCSlp7pRcS6zLpjuqqTTyre2ziYrwAQAwlqgUARBa/rkdRfmgx1qrtg7peIvV8VarExmrkxmrE61WrWel4eQmli12ddNVjhLu6K7OrbXadaRHh05lR/U8paAsYXIJkBpX42tclSVIggAAACBcqCIpvkl10typuSTIvGmOqitycYNvxbB0AEBJoFIEQGg5xkjnXVMbY5SqkmorpTlTjIxz7jHKJSc6u6W2jlyCJNOea8HV1mFz/7RLnd25x3T25CpFCnGf3xgjL6SVIhVJo5oKR/XVjsbXuKosz80G8a3tfV9JhgAAACBMBqoiaTljlT7u69BJq0MnrQ6fsmrvCnixIWAkTa43mjPVaO5UR/OmGVWVm4taYhljNMr9ZgAAFAyVIgBiJ79LSVZynIFv7Pu+LUhf2+b9XTrRVqC+XkXgOFJNuaPqitwurtqK3H/nA8bzkyAAAABAVPnnNjPlY4C29lzL3kMn30+WtHUEucJgOUaqr5Em1RlNqjOada4lVmXZxUkQAABKGUkRACiyt/Z26vTZ0mhYXH6u+qO6wqim3FFtpaPypJExBDIAAADAhXzfyur9CpP2LquDJ3L/HDrl6/BJq9Nngl1joZUlpInnEh/5f6aMk8bVmvc3Tl2QQAIAIExIigBAkW3Z3alMR/GTIq6TS3qUJ4zKLvh3RZlRRfL9GSnMAgEAAABG5sL5GD3ZXAVJyxmr1rNWmfZcu97cP7n/PtMhldLdl2RCqi6XJqRMbwJkcn3un5rK92MEz7MyhuQHACBaSIoAQJHtONils51WvrXyfck792/f5krQHZNLTjgm18qqz/8/F4AY8/5jXceoPGlUlsj9uyJplEyYi4YW+vnEh0h+AAAAAGPB822/bXp9a9XemUuQtJzpmzTp6rHKelLWk3o8KZuVsp7N/fe5Lrz5Ozf23P/kb+Q4RqoqlyrKjarKpMpyo8oyqbL8/P82qq6Qqs79//KyvgPPfWtl/cFbCwMAECUkRQCgiKy1BQ8s8m2ujCFoAQAAAMImn4SQ0UUbmwr5/Fbq3VxF3AAAwPtIigAAAAAAAAAAgFhwgl4AAAAAAAAAAADAWCApAgAAAAAAAAAAYoGkCAAAAAAAAAAAiAWSIgAAAAAAAAAAIBZIigAAAAAAAAAAgFggKQIAAAAAAAAAAGKBpAgAAAAAAAAAAIgFkiIAAAAAAAAAACAWSIoAAAAAAAAAAIBYICkCAAAAAAAAAABigaQIAAAAAAAAAACIBZIiAAAAAAAAAAAgFkiKAAAAAAAAAACAWCApAgAAAAAAAAAAYoGkCAAAAAAAAAAAiAWSIgAAAAAAAAAAIBZIigAAAAAAAAAAgFggKQIAAAAAAAAAAGKBpAgAAAAAAAAAAIgFkiIAAAAAAAAAACAWSIoAAAAAAAAAAIBYICkCAAAAAAAAAABigaQIAAAAAAAAAACIBZIiAAAAAAAAAAAgFkiKAAAAAAAAAACAWCApAgAAAAAAAAAAYoGkCAAAAAAAAAAAiAWSIgAAAAAAAAAAIBZIigAAAAAAAAAAgFggKQIAAAAAAAAAAGKBpAgAAAAAAAAAAIgFkiIAAAAAAAAAACAWSIoAAAAAAAAAAIBYICkCAAAAAAAAAABigaQIAAAAAAAAAACIBZIiAAAAAAAAAAAgFhJBLwCIm+bmZq1bt06bN29WOp1WXV2dJGnhwoW66667tHTp0t7HZjIZPfHEE3r44YcLuoannnpKTz755EVfz6+ltbV1SF+XpNtvv12PPvpoQddXalatWqWtW7cqk8konU7r1VdfVSqVCnpZRTHan/WBBx7QgQMHlMlk1NraqldffbWIqwUQpJ6eHnmeF/QyEFKO4yiZTMoYE/RSAIyB5uZm3X333cpkMn2+nkqlemMNKRdvZDIZNTQ09Bsfsc7i43oeQBCILTAaI4ktSIoAYySdTmvVqlXatGmTVq5cqb/4i79QY2Njn+8/++yzevbZZ/Wtb31LqVRKa9asKdpaMpmMli1bpvvvv18NDQ19bnyn02nddtttkqTHHntMy5cv7/Pn84mdp59+Wlu3bi3KGkvJypUr1djYqFWrVgW9lKIb7c9611139f6uA4imTCajEydOqKurK+ilIORc11VVVZUmT56ssrKyoJcDoIgaGxt7b66vWLFCzc3NWrly5YCbq/LxxoMPPqiGhgY99thjamhoYJ1jgOt5AGOJ2AKFMtzYgqQIMAY2bNigBx98UI2NjXruuef6vVBuaGjQww8/rE2bNunBBx/UQw89pKamJq1cubLg60mn04Ne3J+/vv7W2tjYqMbGRtXX16upqang6ys1+Z/3pZde0saNG4NeTlEN5WdNp9O65557tHDhQj3++ON9vpffIdfU1KTm5uairxfA2MpkMjp48KBqamo0ceJEdvpjRKy18jxPHR0dam1t1d69ezVz5kxVVVUFvTQAY2DmzJlqbm5WbW3tgI/JX5Pef//9uvvuu3Xbbbdp7dq1fTaVsc7i4HoewFghtkAhjDS2ICkCFFlTU5NWrVqlxsZGrV279pKPX7p0qerq6rRixYqiram1tVWPPfbYkB47WOuk++67LxZJkbHywAMPXJRkKEUbNmxQOp1WOp0e8DHntxcAEB0nTpxQTU2NZs6cScCCUaupqdH48eO1b98+nThxQrNmzQp6SQDGQH19fZ9/DyaVSmnt2rW67bbbtGLFigE3mBVDqa5zrGIGrucBFBuxBQppuLEFg9aBImpubtaqVauUSqX0/e9/f8h/rrGxUffee2/R1lVXV1ewmRhhLw8fjqEERKNx4MCBoj7/cAz2s65cuXLQSiMA0dTT06Ouri7V1dURtKBgXNfV+PHjdfbsWWWz2aCXA6BE5Td0PfjggwGvZHBjsc5SihkAYKSILVAMw4ktSIoARZS/GH7ooYeGnYR4+OGHizbMe7AS8OGKU1Kk2AarvCglqVRKjz76aFFauwEoXfnBh8lkMuCVIGrKy8sliaQIgAE1NjZq6dKlam5uLulK9bFYZ1hiBgAYDLEFimWosQVJEaBImpqalE6nlUqlRnzz+KabbirwqnIKWfHQ0NDAhXkBbNq0SZlMJuhlAMAlsZMLhcbvFIChuO+++yRJTz31VMArGVwx10nMACBquA5EoQ31d4qkCFAk+Z1Bt99++4if4+abby7UcvpYvnx5wZ4rPwMFo1PqwR0AAAAQpPwA8HQ6rU2bNgW8moEVc53EDAAAFAZJEaAIMpmMmpubJb1/UTwSt99+e0FbXeWNZk0XamxsLFqbr7hYtWpVSQd2AAAAQCnIt+596aWXAl7J4IqxTmIGAAAKJxH0AoAo2rp1a+9/j2bmRiqV0sMPP1yIJY2ZTZs26dlnn+3Toqu2tvain2PVqlXaunWrMpmM0um0du7cKSm3+6mlpUVtbW3aunWrZs6cqYcffrj3fUyn03r22Wd7//vAgQO66aabBnyfHnjgAR04cECZTEatra169dVXlclk9MQTT6itrU0tLS3atm2bli5dqvvuu2/UM1I2bNigt99+W5J6n//+++9XY2PjRY9tamq6aLfXkiVL+lTeLF26dMCB5kN9rwvpqaee0qZNm5ROp5VOp/Xqq69eMimWyWTU1NSklpYWSbm/t/r6+gFn7Zz/dyZJzz33nDKZjNasWaPa2lql02ndcccd/VY8Def9H+5rrVq1SuvXr7/oOZ5//vmLfo4VK1aoublZqVRKmUxGy5Yt0+OPPz7o+wQAAIDB5Vv3btu2LeilDOpS6xzLmGG418f9Ge71/GhfPx/zzZo1q/c6vaWlRXfccYc2bdqkpUuX9vvng4iPAADhRFIEKILzZ2zEqYpi9erV2rx5sx577LE+yYVVq1bptttu0zPPPNP79ZUrV2rp0qW9w+jzj7swMXHPPfdoxYoVev7555VOp7Vu3bo+F7WZTEa33nqr0ul0vzed77//fqXT6d7XSafT2rBhQ79JmhUrVugv/uIvRtxebPXq1br55pv7PHdzc7Puvvtu3X777RcFKitXruydN3PPPfdo06ZNevXVV4f8WkN9rwtp6dKlamho0COPPDKkxzc3N2vTpk29vZXzNmzYoFtvvbXf9/v+++/X1q1btWrVKjU0NCiTyejP/uzP9PjjjyuTyWjJkiXauHFjbyItb7jv/3Bf69FHH9Wjjz6qVatWqampadBEx9q1a7VixQplMhl9//vfH1bQCURBPuGYr5pctmxZn++3tbVp5cqVBW3nOFYymYxWrFihlStXXnRsC8rq1avV1tbW+/8bGhp033336amnntLy5cuLcj4AgCDkq+hLfabhYOsc65hhuNfHFxrJ9fxoXn/Dhg1at25dv9fZq1ev1tNPP621a9f2+70g4iMAxUdsMbZiE1tYAAX35JNP2vnz59v58+fb1tbWoJczIvn179+/f0iP//a3vz3o42+99VZ75513XvT1u+++286fP99++9vf7ve92rp1a+/3H3nkkRG9trXW3nnnnb3PM5BvfvObdv78+fall17q9/uPPPLIgH+n69evt+vXr+/3z61fv97Onz/fPvvsswO+dv59GIqRvtfDMdjPau3779VA3z//73Ug+fdloPf7zjvvtLfeeutFf+/f/OY3L3re0b7/w3mt1tZWO3/+fHv33XcP+HzW5t7DrVu3DvoYIEw6Ojrstm3bbEdHx5D/zPz58/s9HrW2tto777zT3nnnnSV7nhzo+LV//347f/58+81vfnOMV9S/O++886Lj3/79+3uP0/2dKwY7NgdhJL9bAMIrf5355JNPjvjPLl68uAgr6/+1CrnOsYwZCvVaI72eH+nrL168eNBrg1tvvfWia+yxiI8AFBaxRQ6xReEN9XeLmSJAEZxfHdLa2hrgSsZGOp3W008/rXvvvXfAjPF9993Xu8vofOfPTOmvqia/w/7pp5/u3SF1oWuuuUaSBu2xmy8vv+uuuwZ8TH4H06pVqwZ8zEA2bdqkRx55pN815HcrNDU1Dft5LzSa97qQzi9JH8z9998/4PfyOwwGer/r6uqUTqcv+jkff/zxiyp9Rvv+D+e1UqmUli1b1ttGbDBUiAD9S6VS+v73v9+7W7QUDfT5bmho0M6dO0uiJd5TTz2lmTNnXrQrrqGhYdBWIaW+wxoALuX81lGl7MJ1jlXMUMjXGun1/EheP5PJ9LY9HsiFO8RLJT4CEBxii8KIW2xBUgQogvMvxvI9UKNs9erVkqSbb755wMdcffXVkgYeNjjYn8271A3mobzXg5X5NTQ0aNmyZUqn08MORlpaWpTJZHrLOft77kKcKArxXo+lS7WPG8r7vXTp0ku+TqHe/6G8lvR+ci0/3+ZCGzZsCGXpLjCWUqmUUqmUmpubS+5cuWHDhj4l46Vq06ZNA57X8ue0C4XlZwOA/uRnWpR6i+KB1jlWMUMhX2uk1/Mjef38az344IMDXhvccccdfdYUtvgIQHEQW4xe3GILkiJAEeQvuqTRZ0wHuogsJfkBguf/3BfKH1gHGjZ4qZ6Eg32/kEFRvupkuBfM3/rWt/TYY48N2AMyP3B7tArxXpeSWbNmSRr8/R5Kv8pCvf9D7Y2Zn63ywx/+sN/vr1u3bsgJFiDO8p/LUrq5lU6nhzw3qRRs3rx5wO9deIMobD8bAFwof+NlsGvhUjDQOscqZhjL1xroen6kr//oo4+qublZS5Ys0YoVK7R69eo+FR6NjY19rtmjFh8BGDlii9GLU2zBoHWgCFKplBobG3tLdEe6YzyTyaipqWlIA/CClE/8PPHEE4O2VXrooYcGvOl8qRL4sTqp5dd34MCBYf25VCrV+/ecH+b+9ttv9z5foXZ8FeK9LiX5v/fB3u+h/N0X6v0fzu/ZypUrtWbNmouqQtLpdG9yDcDANmzYICl3vOpPJpPRmjVr1NDQoJaWFqXTad1///0XVQ2m02k9++yzqq+v792ZO1h5d1NTk5qbm3vbN9588829Scz8cFdJ2rp1qx544AFJ75eMp9NprVq1Slu3blVDQ0O/g16feuqp3v9uaWnRrFmz+rR/bG5u1iOPPKJ0Oq2bbrpJ3/rWt9TU1KRUKqWXXnrpkuXp51u+fLlWrVqlVatW6aGHHrroGHb+617qZ8u71Pu+adMmrVmzpnf9d911V++NsHwbwqGuHwCGK39zvNQ3nwy0zrGKGcbytQa6nh/p669cuVINDQ1as2aNmpub1dzcrKefflpSrirlW9/6Vp/zXdTiIwAjQ2xBbDFcJEWAIlm5cqVWrVql9evXjzipkU6nS34mwfm7e+6///6SysiPtQ0bNvQe7O+7774+u6I2b9486qof3uvBFfv9v1A+KfLkk0/2SYo8++yzg/ZeBuIuf2Nk/fr1euyxx/rdOJBOp7VixQp9//vf7z0P9vc1KRconH+eXb16tVasWNFvUPHAAw+ovr7+osdLuRtXy5cv1/Lly3XPPfdI0kW9fRsaGvTMM8/onnvu6bff+YoVK/S1r32tz8+0evVqPfDAA73P1djYqLVr1+qee+5RW1ubmpqaeo9XK1eu1JIlS1RfXz/gztrzrVy5Uhs2bFBTU5OamprU0NCgpUuX9v4s57vUzyYN7X1funSp1q5dqxUrVmjz5s26+eab+wQqDzzwwIDvPwCMxvnXcqXcpvRS6xzLa9axvj4u1OvnzzWZTEabNm3S22+/rc2bN2vjxo3avHmz1q5dq4aGBuIjAMQWxBYjRvssoEjyO1zy1R4j0dTUVPK7oKJ24fn2229LkmbOnDmsP7dq1So9+OCDWrlypZ555pmC/b01NTX17n6K2nstqffEP9z3+0LFev8Hkx+4nt/BltfW1hbJvytgpDKZjJ566qnef1avXq3169frL/7iLwa8qbVq1SrddNNNfQKUhoYG3XTTTVqzZk3v1zZt2qSmpqY+bTXuv/9+NTc39+4Wy2tqatLGjRsv2j22cePGAecDDaS/naarVq1SXV3dRT/Tww8/rM2bN1+0ntra2n6rSa+++mqtX79+yGt55pln9Oijj6qxsbG3p/uDDz6oJUuWDPtm11Dfdym3M7ihoaHPjjEp1y6lubm5NyAEgELJ70i99957A17J4AZb51jEDMV+rQsNdD0/ktfPZDJ9zpf5apOHH35Ya9eu1TPPPKNMJtM72J1rbiB+iC2ILQqFpAhQRI899pgkac2aNcPu15pOp9XS0hKKEt/8sKWtW7cGvJLRy/eZHcrg97z8iXPp0qUDZt8v/Ptvbm4eUcl6lN5r6f2ddHfccceIn2Ms3/8L5StC8olPBqwDF0ulUr27Q++77z49/vjj+trXvqYVK1ZcdDEvqXdXaH9t6G6++eY+x7/87qXzz5X5GyQXfsbXrFmjZcuWXXQDZeHChaM6BuU1NTUN+Pnv78K/vr5eqVTqovP8SM77K1eu1Nq1a7Vz504988wzuvfee5XJZLRixYohX38M533P66/1ZT5hPNDMJQAYiUwmo6efflqpVKqkK3IHW+dYXrOO5Wv1dz0/0tffvn37oBsKly5dqoceeqjPDcuoxUcABkdsQWxRKCRFgCJqbGzUo48+qkwmo7vvvntYf3bVqlWh6cmdX+elsuGZTCbwnaODHcDT6bQ2bdrUb3Z6MPkT72A3wy88gabT6X7XcuHXMplMnxNDmN7r/DoGs379ejU2No4qkVDI93+48oMe88EbA9aBoVm+fLkaGxv7HcyXv0DO70w6/x+pb5/gfMl5vjLz/F1c+R7AUu5YlMlk+g0KHn/88VEnM/M3hAaaj1VfX9/vjaZLzdMaiaVLl+rhhx/WM888IynXY30ohvO+X0r+76NQw4IB4MEHH5SU23RWytUBg61zLGOGYr7Whfq7nh/p6585c6ZPwqM/S5cu7fPehi0+AlB4xBYa9PGjEeXYgqQIUGQrV67UY489pubmZq1YseKSu28ymYweeOAB3XfffQNmdJuamnpLhottKAedhoYGPfroo9q4ceOgF7FPPPGE7rrrrkIuT9LQ1nj+GgaSv0jOH+wvdP5J8Hz5v6eB1rFhw4aLZsO0trb2uZjP30jvLzg4/3Fj9V4P9LMO9ftSLqM/2Pv91FNPKZPJ9FZUjVQh3v/RyO9+W7VqFQPWgWGYOXOmMpnMRce9/MX80qVLtXLlyn7/Od+GDRt0zz339B5vli9fftHnO9/aY7ABrIO51Hmmvx7AQzHa49BgN3fy/X/zFZADyf9sw33fAWCk8teRQ7mezGQyuueee7Rp0yY99thjg24+KXSMVOh1jnXMMNrXkkZ+PT/S16+pqZE0+PktP4z3/NcKMhYFUBqILYgthoukCDAGli9frueee051dXW67bbbtGrVqot68aXTaT311FO6++67df/99w94wZ/voXp+hrXQzr+YvNROnbyVK1fq0Ucf1YMPPthvyeLq1at18803X5ToOXDggKSLL+zz8gfUwZJJ+e8Npdz75ptv7vd9e+CBB7Rt27beXQH9GWitK1euVCqV0pNPPnnR9zZt2qR0Oq2vfe1rkt7fNdXc3NzndfIzaM4vgbzwMec/diTv9XBc6u/lUt+Xcpn/O+64o9/3O//7mx+S2J+h/r0W4v0fzu9Qf6+f/5lK4cQOhM2F58Pzh/BdSlNTkx555BE9+uijevjhhy+6wZKX/7yPtG3e1q1bB/2zV1999aDPX6x2mJcKShYuXKja2tpBH5P/2Ybzvg9lXalUqqR3cwMITv46sq2tbcDH5GOjW2+9Vel0WmvXrh10520xYqRCr3MsY4ZCvJY08uv5kb7+9OnTJal3WPCFmpub9eSTT+pb3/rWRa9X7PgIQDgQW4xc3GKLREGfDcCA8mV4zc3NWrdunR555BGl0+ne7Gm+ZdPatWsHfZ5UKqWlS5cqnU4XtE1PPinQ2traJ2u9Zs0aPfnkk73rfO655wZ8jpUrV2rp0qV66qmn1NTU1OcgfWHlS75qJv9ad999t+rq6vToo49q6dKlam5u1oMPPtibIc9kMlqyZInq6up615B/nfxBtqmpSevXr9ftt9+uRx99tN815t+7/C6y2tpatbW16ZprrtHjjz/e75+51FpTqZSef/55PfHEE3rwwQd19dVX954orrnmmt5KgkcffVRPPvmk1q1bd1FrtFQqpWeeeUarVq3SPffco4aGBjU0NAzYg3c47/VwXOpnHej7a9eu7XOCWrhwYW+CIJVKafXq1aqvr1dLS4va2trU0NAw4O/Sbbfd1uf3cMWKFaqrq9PChQv7/Tsazfs/3NcayMqVK9XS0sINQGAY8jurzr9Qbm5uVmNjo+699141NTX1ewxctWpV7zF+zZo1uv322y865p1/Hnvqqad03333admyZQMm+i9MaubPDec/32Dl6Plet+vXr+93zRs3bhzwvDQara2tgyZkN2/e3HvTKW+wn22o7/v5r3+hfP/g4ZTEA4i+/LX9+cf8/LX7hcfXdDqthoYGLVy4cNDBuecrVIxUzHWOZcxQiNcazfX8aF7/3nvv1cMPP6xNmzb1idnyBoqXixUfAQgHYovRi11sYQEgBu6++247f/78oJeBiHr22Wft1q1bg14GUFQdHR1227ZttqOj45KPbW1ttS+99JKdP3++Xbx4sd2/f79tbW3t85itW7fa+fPn27vvvrv3a9/+9rd7//vOO++0Tz75ZJ8/s379evvSSy/1/v9bb721z5/PP+buu++2jzzyiLXW9j5Ha2urvfXWW/u8Rn4d/3/27jvOrvK69//32fuc6U1do16QQBJNIGxDXDBgjLkhsYmxU33d/buxcfJznJvcxJXkJvkFTGKT8sLY4BbbFAMONr0IMKIJSRRV1Ee9zJzp5Zz9PL8/jmZQmZFmRjOz2+f9evkl68yZM8+Ic/bea69nrfXQQw8d89jPf/5zt2zZsr6/H7+Or371q+7yyy8/4Xe+/PLL3c9//vMTnnv8Gp1z7vrrrz/hNU72eH8+9KEPueuvv9798z//8wn/vt/97nf7/bmn+t0G8+/uXPG8umzZshMev/766/v9uSczlPcWAAAA4o/Y4i3EFuHEFsY550Y+1QIA0dLb43fjxo1hLwUJ1N8uByBpurq6tG3bNs2dO1dlZWUnfW5//Wjr6upO2CW0YsUK3XbbbVq8eLEk6fd///eP2ZnV+zq9O78uueSSY8rYW1pa9JWvfEWtra19O4N7d+p+7Wtf0+LFi/W5z33umCquG2+8sW+Ha01NjWbOnNnvruIbb7xR69at6/uZvTuQb7zxRj3//PNqaWnR+9//fn3uc587Zk1Hr7m3dPzo3Vb9vUbv73304739d0+287j32NPQ0KCf//znfbu0crncMTtxB/O7Hf/1k/27S8XzqlTcfdvbv7m/33cwhvLeAgAAQPwRWxBbHC2M2IKkCIBUICmC0dLQ0KAVK1YwTwSJx41rHK03cLnjjjtO+7V4bwEAAKQL1384WhixBYPWAQAYpP56ht522236wAc+EMJqAAAAAAAAMFQkRQAAGIQbb7xRn/jEJ3Tbbbf1PdZbzsmAdQAAAAAAgHggKQIgFRoaGiRJa9euDXkliKtzzjlHM2fO7OvB2dLSohtvvJG2WQBSqbm5Wc3NzWEvAwAAAEDMhRFbZMb0pwHAGLviiivU3NyslpYWSdLHP/5x1dbW6oYbbuh3+BUwkKuuuqpv4Fivv//7vw9xRQAw9tauXatbb721b5PBF7/4Rf3+7/8+51QAAAAAQxJmbMGgdQAAAJwSwxAxWnhvAQAApAvXfxgtDFoHAAAAAAAAAAA4CkkRAAAAAAAAAACQCiRFAAAAAAAAAABAKpAUAQAAAAAAAAAAqUBSBAAAAAAAAAAApAJJEQAAAAAAAAAAkAokRQAAAAAAAAAAQCqQFAEAAAAAAAAAAKlAUgQAAAAAAAAAAKQCSREAAADEnrUu7CUMSdzWCwAAAKRF3K7V47beKMiEvQAAAADgdHme0d3PFHQgF/2AYHKd0XXv5jIcAAAAiCJii+TjXwwAAACJcCDntLcx+oHLaGhpadFXvvIVXX311brqqqvCXg4AAAAQa8QWyY4tSIoAAAAAMfXFL35RdXV1kqRHHnlEV199dbgLAgAAABBLaYotSIoAAAAAMfWd73xHktTQ0KA777wz5NUAAAAAiKs0xRYMWgcAAAAAAAAAAKlAUgQAAAAAAAAAAKQCSREAAAAAAAAAAJAKJEUAAAAAAAAAAEAqkBQBgFHkgsKxf3fumP9/9N8BAAAAYDCIIwAAGL5M2AsAgKTrfu0FdT3zgLILz1PFlR856itOhaYDMp4ved6RP30Zz5P8jEwmK2OOzV07ZyUnyRgZY8b09wAAAAAQDcYYOefU/vozkpGqznlP39esdSoETvlA8jzJM5LnmeKfRifEEcXNWpLp52sAACQRSREAGGW2pVG2uVG2pfHYLwSBurauOen3mkxWJlsqky2TyZbKy5bKZEuKj5WUycuWFf/u+X3fU9w15k5IqAAAAABIFtfTWfzT2beu/420Nxdo+4F8v9/jGakkY1SaNX1/lmaNSjNGZSVGpVlPWf/YBAmJEwBAkpAUAYCxclTiQjpS9XEKrpCXK+SlzrZTvrbJlskrLZdXXiW/vFpeZY280spi5YkkZy0VJgAAAEACnVhhPnB7LeukrrxTV/7kLbj6EiZHJ06yRlVlnspLTF+1ipPkEWMAAGKEpAgAjBHjH3fIHck+wDaQ625X0N2uoOWQ3toTZuSVVcgrr5ZXXiWvvFp+RY1MSVlfENO75YtkCQAAABBD/VzHj0So0VNw6ik4tfbzNc9IVWWeqso9VZV5qin3VFFKogQAEA8kRQBgrBxXKaJBVIqcPifb1S7b1S41HbuWYkXJkURJ9Xh55dXFIMbavuoSAAAAABF3XJWIUbEaZDRZJ7V0WrV0vhXTGCNVlnqqLi9Wk1SXe6os8+SRKAEARAxJEQAYK74v51xfRcbJStpHnQ1k25tl25vfeszPKFM9Xn71ePk1E+WXV0kSSRIAsTG5Lh43WkZjnS0tLZKk5ubmUzwTAJA4o1QpMlTOSW1dVm1dkhRIKiZoKkqNqsqLSZLxVb7KS7y+WIhqdQBRRWyR7NiCpAgAjJHiMHSnYmigcCKVkwkKKuQOqJA7IKk45N2vHi+/eoIyNRPllVVIIkkCIJqsdbru3fG5tLXWyfNOP4C58cYb1dDQoHXr1kmSbrrpJj333HOqq6vTDTfccNqvDwCIvuPniUijXykyWE5Se7dTe3eg/blAUl5lJUbjq3xNqPZVV+HJ84ysc1SRAIgMYovkxxbx+a8LAHHn+cfkRMamfdbwuUJehab9KjTtV7ckky09kiQZr0ztRHkl5ezwAhAZIxEEjKWRWu9f/uVfjsjrAABi7Lhr8b7ZgRHV1eO0p7GgPY0FeUaqq/T6kiRlVJEAiABii+QjKQIAY8XvrRQ5IuJJkeO5fLcKjXtVaNxbTJKUVig7booy4+vlV9QQvAAAAABh6KdSJMI5kWNYJzW2WTW2WW3el1f5UVUktZXFeSRUkQAARhpJEQDoh3NOzhWDCae3Nl8dfyk+lGy86a0U6f0ZUalpHybX3aGefdvUs2+bTEmZMuOmKDOuXn5lbd9zSJAAAAAAoyzC7bOGqrPHaXdjQbuPriKp9jWp2ldJ1iNBAgAYESRFAKSCc07WSjKSf1wioxA49eSlnkKxlLurR8X/5Z2681J3XurJO+WDt5IkzklXv80f2iJiXilyMq6nS/n9O5Tfv0MmW6rMuKnKTpgmv7KWChIAAABgFPV3nR2XSpGTOaaKZG9edRWeptRlNKnWl+8VW4QRYwAAhoOkCIDEsNbJ6dikR0e3U0uHU3OblGt3au1wau6QWtqLj7d0FJMew/GBi/wTS0dOxjsuiZKgpMjRXL5b+QM7lD+wo9hia3y9shOny5RWyDnb7yBIAAAAAMPkxbd91lDkOqxyHT16c680scbXlLqMxlW+9buTIAEADBZJEQCxc3zyw1qnpjZpX6PTgWang7nin4ebi9UdUWGOD1aSGKkcx3V3qGfvFvXs3SKvokbZCdOVnTijL3AjcAEAAABOUz/X1DbBsYZ10oHmQAeaA5VkjKbU+qofn1F5CfNHAACDQ1IEQKQ552TdWwmQtk6nHQec9hy2fcmPxpaY9Mz136oUKc4sSWalyEBsR4u6O1rUvXuTshOmq2TKHJkyqkcAAACA09HftXQcwqOR0FNwajhcUMPhguoqPNWPz2hijd9X0M8mLABAf0iKAIiUwDp5pnjxWgicdh922rnfqeGQ1a6DxXZXsXVC+6y0hCrHsYHyB3cqf3Cn/JqJKpk8W37tREmO5AgAAAAwVP1WioSwjpD1ttfK+tKUuoymUT0CABgASREAobJHrtY9z6i9y+nN3VY7DjjtOui0v8kl6mLe+EcnRVxiZ4oMRdBySJ0th2RKK1QyedaR1lrFfyd2dQEAAACD0F+lSILiqKHKB9KuwwXtOlxQXaWnWROzGlflkxwBAPQhKQJgzAXWyfeMgsBp+36nTbutNu8pJkESzc+obzK7U7ojleO47g51N2xQ9+43lZ0w7UhrrUpaawEAACAVAuv0+GOP6/HHH1NPvkdrVq/WhAkT9Pa3v12S9L//9/+Wc8XNZCc46kb/448/rgceeECvb9ihxsbDkqRZcxeqpblJf/Tpv9DCxUvH5PeJily7Va69W9XlnmZPympCNckRAABJEQBjwFonc6Ql1oGc1cZdTpuPVIQUIjQIfagef/xxPfnE45o/f75yuZykYrAyIM/vy4lIUlMup1t/dLcam1skSc2t7WpqadWXPv5RnX/WGaO48gizgfIHG5Q/2CC/ZsKR1lqTRGstAAAAxIlzTvZIYbjnnVgFHVinzm6pvavYIvj+e+/Rgw/cpXe/7zq9+Mjd+ttvPaFXXnxCP//Rjbr2j/5SS9/+Pq156fF+f1bvdfI999yjn/zkJzrzzDP1lX/8T/mltVr5/JP62fdv1jUf+ZQ++5F36qbbHtCyiy8b1d89ilo7rd7Y2a2qMqNZk7KaVJMhOQIAKUZSBMCo6E2EOEk7Dzi9vt1q3Q6r1s6wVzYy1r98rzbs/4Xuuefuvscef/xxve9979Njjz3W7/cYz1dvViSXy+mf//Xf9Ge/9wHVVVf1Pef+J57Vu//kev3y3/5B7317unZxHS9oOazOlsPyyqpUMn2BsuOmUDkCAACAyOhNfPQmPZwrJjha2p1aO6XWTqf2rmLio+3I/2/rdGrrkrp63nqdro6c/v2vP6dPffMl/fPX36bP37hRz75hpcr3at/+/6PnV23R/gON+u53v6vPfvazJy7E85TL5fSZz3xGX//61/XNb35T77jyf2r81Fotu/gyffdfvqrW5iZV1dTpu//y1VQmRXq1dTmta+hRRWlesyZmNbnWl5NIjgBAypAUATBijk6E7NhfTISs3WHV3hX2ykZWV0dOD/7gf2lXw9ZjHr/iiiv0V3/1VwMHK77fV9p+11136fs/+Zk+dsXbj0mKfPDyd6muukpf/7fb9d633zKqv0dc2K42dW1ZrZ6KGpVOX6hM7USSIwAAABhTgXUyeqt9VWe3095Gp31NxTbA+5qcDuSc8oWhv/a6l+5R3aS52vrGY6qbNFdlFXV9X1v8tg9r9fLvafHbPqxbb721/zjDGN11112aN2+ezj77bElSS0tO46cWv/zeq35PD9z9/aEvLME6up027O7R9oNGsyZmNbWO5AgApAlJEQCnxR2Zi+GctG2/0xvbrNbtTF4i5Gi9QUtdXd0JX/voRz86cLDi+X1l8/PmzZMkNbe1j+ZSE8V2tKjzzZXyq8apZMZCZarGyTnHQHYAAACMGOecrJP8I8mPQuB0sNlp7+FjEyAjGe9sePkXKq8c1/fn0eomzdO+Hau17IrP68lVq5TL5U6IQ4zxdPfdd2v8+PG64oor1NTUpOc3dqqnUIzV6mfM1aZ1ayRJZy65YOQWngBdPU6b9vRox0GjmRMyqh+fkdGJ7c4AAMlCUgTAsPQOSz/c4vTSRqs1W6w6usNe1djoL1jpNW/ePK0aKFjx/b7/f8UVV2jfulXq2fPmCa+Ra23T0kULRnTNSRK0Nalzw4vyayaqdMZC+RU1JEcAxO44ELf1AkCS9cY2gXVqOOi0ba/T3iar/U1Oja3FDWCjae/2VVp00e9p/cu/0KKLfu+Yr9VNmitJ8vzi7ZutW7fqgguOS2wYo5UrV+ojH/lI30PuqEVPmzGn7///wSe/NMKrT4buvNPmfXntPFTQjAkZTR+fkQyVI0Baxe1aPW7rjQKSIgAGzbpiyXghkF7barXyTauGg6McIURQb9DSn94KkH6DFf+4Q66zJ3z/v/6oOKPkzz923ekvNOGClkPqWHdImbopKp2xUKaskgsBIMWMMVq/q1sd3SceW6OmotTTohmlYS8DAFKrNwkiSQdyVpt2OW3Za7V9//DaX52uro6cyirq+v7sT2vTHkkDJUW8EzZl2aPCtPb2NknSdf/zi5o2c+5ILj1xegpOW/fntetwQfOnZjW5NkOMAaQQsUXykRQBcEq9QcPew04vb7R6fbtVdz7sVYXnZMFKr/6TIm9VisjohC1nudY23X7vg/rRP/2N5s6oH5nFpkAht1+F3H5lJkxT6fQFUrZMEiXvQBp1dFu1dcUhWT+ywVVLS4tuvfVWtba2qqGhQc3NzfrsZz+rq666akR/DgDEVe/sQ2OM2jqdNu2y2rzHaes+q7bOsFd3cmUVtZIkGxQDsMbGxhOf1M91b0tzTv999+3a07BN+/fukiTNmkM1+mD1FJzW7+rR3saCFkwrUXlJ8XFiDCA9iC2SHVuQFAHQr95y63wgvfKm1cpNxfJxnFzv7qz+ghVzXKWIc1a51jb94L6HtG3XXjW1tOqX//YPJESGqXB4jwqNe5WdOFOlMxbKeR7D2AEkXktLi2666SZ9+ctfVk1NjSRp7dq1uvbaa/X+979f3/nOd0JeIQCMPeecnCsORe/JO23Z67R5j9WWPVaHWsJe3cjr75q3srqur1XWI//9U730m0e1cd1qXTPWi4u5XIfVys1dmjYho7mTs/JE1QiA5EpTbEFSBMAxrHXyPKOWDum5tYFeeTPdVSEjyjuqUkRGck511VV9rbKeenG1/vwfb9Enrv2APnj5u8JZY9w5p/zBnSrk9qt05lnKjq+n3B1Aot16663HBC2StGTJEn35y1/WTTfdpBUrVuiSSy4JcYUAMHZ6K9wPtTi9trVYDbL7kDumlVTcdHU0S5I8PytJGj9+/IlP8k6+EWjuGYskSb+6+3aduXiprrnukyO7yIRzknYfLuhgc0Fzp5Roah0ttQAkU5piC5IiACQd1SKr0emZ1wtavzPewUNYcrmcpP6DlaMHrUs6oX3We9++VEsXL9Csy67Tt//P9frEtVeP1jJP8NSLq3X/E8+qtrpSza3tqq2u1A3Xf2pIr3H/E8/qqRdXH/PYN6//pOqqq0ZyqYPi8t3q2vqq8od2q2z2EqmkjKAFQCI98sgjeuSRR/T4448f83hvsPLwww8nJnABgP70xjG5dqc1m61e32a1P5eyQOa461w7wGT4xee+Td/65vW69P3XqrqmbgwWliw9BWnj7h7tbSpoYX2JKo608CfOAJAUaYotSIoAKdcbRGzd6/T0awVt35+yAGIsHdU+yxjT76D1uuoqffDyd+rP/vEWfeh97x6ThMK//uhuPfXiav3y3//hmMc+9tf/Vz/6p78d1Gt87Zbv671vu0Df/psv9j22bdde/c6f/h/993/8YyiJEak4jL197bMqqT9DJVPnSnK01AKQKDNnztQbb7xxwuO9u7t6k/UAkCS9MUx7l9OrW61e22q161B845i6SXPVdHBb359H62ovtuUtLSteT8+bN++E7zfG07x587R161ZJJ+y9UktzkyTprHMu1LrXXtIrLzylS6/80Ej/Gsdobcnpu//yVVVV1+pzX/r7AZ+38vkn9crzT2razHlqa81JUl/br8Fa+fyTevrR+1RVXau21uZT/szT1dJhtXJLl6aNL7bU8j2qRgAkQ5piC5IiQEoF1skz0trtVk+/zryQoegvWOnVO0ukv2Dl2PZZb81tOd4Fixfq/id+o+UvrR71NlprNmzW1265Xa/ed/sxj//5x67TrMuu0/1PPHvKNazZsFlSsdLlaHNn1Os7f/tn+uL//fagkyujwlr17N6kwuE9KptztvyqOsrdASTGHXfc0e/ja9eulSSdc845Y7kcABg11jkZSdZK63ZavfKm1Za97oQEQBxNnb1U3R25vj+P1ht3mCOxxAUXXHDiCxijC5YuVS6X07hx43T55Vfo+m/+sO/Le3dtlyTNPWPxkb/3H8uMhFtv/or27Nqus86+QK88/5QuvPi9Az53+aP36amHf6Fv3vyTvsdWPv+k/uLTv61vfe9Xg/p5P7v9Zq1c8eQxz//Z7Tfr61/642NedzTsaXyrpVb9OFpqAYi/NMUWbJcFUiY40hNrY4PTLb8s6K5nAhIiQ9RfsNKrd3dWf8HK0e2zxo0bpz/6fP87oGqrKiVJ23fvO82VntrNP7hT5591Rr/D3T90xbt0x70PnfI1lr+0WhcsXtjv184/64y+pEnYbFebOja8oK7tb0g2kOunUgcAkuLOO+9UTU2NPvrRj4a9FAA4Lb3xy75GpwdeCPSPd+Z159OBNu9JRkJEkuYuuVxNB7f1/Xm03IGtmrv4MuUObNUVV1zR/wsYT1dccYU2b96sXC6n4/9Z9jRs1YXveK/2NBRjlfoZc0fhtyj63Jf+Xt+8+Sf6g09+SVU1tQM+r7Ulp5u+8QV9+Rv/dszjyy6+TK0tTXrg7tsH+M63bFq3Wrfe/FX9xddvOebxP/jkl/TKC09p+aP3De+XGIJ8IG3a06NVW7vU3u0G3PgGAHGWxNiCpAiQEvZIMLFtr9N/PJDXT58q6EDaeu2OkP6ClV5btmwZOFg5srsrl8sVSw4H+OfftnuvJGnO9Kmnu9RTWv7SmgF/zvlnnaGnXlrd79eON1DyZNuuvZo7/cSES5jyh3ap/fVnVGgsJp1IjgBImhUrVmjFihX6u7/7u2OGJAJAXDhXvLnc1eP0wnqrW+7P6z8eKOiljVZdPWGvbuQtftuH1dXepGnzlqmrvUlNB7b2fW39ynu19NLPaP3Ke/W5z32u/xcwRh/5yEeUy+X0+7//+/rZz+885stPP3q/rvnIp/TKC0+pqqZu1FtnDcbyR+7VtBlz+p1t8t6rfk8P3P39U77Gf33vW1q4+HxNm3likue9779WD9x16tcYKa2dVqu2dmnX4YKkgbsCAEDcJDW2ICkCJFxvMqThkNNtD+b1g8cK2nOYC7TT0Ru09FaFHO2ee+4ZOFjxiofcuro6ffazn9V/3fLP/T5t+UtrjswWGd3WWZKUa20b8Gvjaqsl6ZSVHr972Tv11Eur9bG//r8nvN6//uhu/fnHrjv9hY4wV+hR17bX1LHpZbmeboIWAInyZ3/2Z7rhhht01VVXhb0UABiS3tilpUP69YuB/r+78nro5SDxg9PLKup09cf/U8898P/p6o//p568u9h6dv3L92rcpOIN/3GT5urDH/6wJOm6667T/Pnz9ZGPfETnfvATMsZT3bg63XbbbWpubtaf/q//R60tOUnFFlX1M+aotblJm9at0c2DbEs12pY/cq+qa8b1+7X6GXO1ad2avt9hIK+88NSAVS8LFy/VKy88dbrLHBLnpK3783p1e5fyAYkRAMmQ1NiCpAiQUL0XYPubnH7waF63PVjQjgNclI2E3qDl//z1Xx/z+D333KN58+b1BSu9/uir/6ALvvXTvj7AkvRXf/VX+sJX/u6EJMId9z6oNRs267//4x9H7xc4ymAGoG8/UrkykLkz6nXD9Z/U/U/8Ruf+7if01IvF6pI77n1Q73370hNmjURJ0HJY7Wt/o8LhPZIIXADE3xe/+EV99rOfTVRpO4Dk602GHGpxuvuZgr51T14vbLDKF0Je2BhadNG1uuDST2vvtpWqGTddP/6nK7T2xTs1d8nlyh3cqj/8y2Mrs+vq6op/VldJpnhr58Mf/rC+9KUvqba2Tjd8+WP6s4+/X3fe8a+qqqnTpnWr9cCK3Vq4OBrX5hvXre63wkOSps2YI+nUs0/aTpI0qa4tJlw2rRtc5ftIyrVbrdzcqca2QBIxBoD4SnJswaB1IIGsc2rvkh56qaDXttEaaDQsuuhavWvaBP3VX/2V5s+fX2yHJemxxx7r9/m15SV9lSJScRD7LTf8jf72//5/kqTm1nY1tbRqXE21dj5596CSFSNh6aIFam5t7/drQ5lp8ucfu05zpk/Vx/76H/S7X/gbzZk+Vb/8t3/od1ZJ5NhAXdtfV6H5oMrmnC3neTKGPQMA4ufGG2/UOeeco8985jNhLwUABiWwTr5ntPOg09OvFfTm7nTfPJ675HLNXXL5KZ939913SyrebG975RHJGEnFAd9XXHGFLn7XZVq5uWs0l3ra2lpyqqoeeOaIJO3Ztf2kSZyqflpvDfU1Rks+kN7Y2aNp46zmT83KycljCDuAGEl6bEFSBEiQ3iGEv3nD6unXAvWkaGdVGK644gq9/8r3nfJ5//V3f6Oupx/omynSx1ndcP2nRml1g/PnH7tOv/uFv+n3a6vWbZIkNTW3Duq1aquq9Ocf+7Be3bBFT720Wr/7hb/Rj/7pb3X+WWeM2HpHU6Fpn9rbcyqbd578yjoZghYAMXLnnXeqrq7uhKDlzjvvTOTOLgDxFlgnz0gbG5yeeb2gXYfSnQw5Xcbzjrl2jXthQlV1nSSptbnppM87c/HSAatFTlVlMlb2NBWU6wi0eEapKkpFjAEgFtIQW7AVFkiA3nLzLXucvnNfXo+tIiESSd5xh9wIRCvvfftSfeJDH9DXbjl2COH9Tzyr976tuKOqd7bIyXztlu+rua1NN1z/Kf3y3/9B3/4/12v77n16959c39dOKw5cT5c6N7wk29UuZ6myAhAPK1asUEtLS7+7uFpaWkJYEQD0z1qnwDqt2Wz17fvz+ulTJERGxHE32tPSrukPPvWlAeeGbHhjlaRTJ1bGQke30ytbu7S7kSHsAKIvLbEFlSJAzDnn1Nwh/eqFvDbu4uIqsow5YVeQc9G46f7tv/mi7rj3Qd1x74N9j136tqV6dWNxwHpt1clbefV+39GD4T9x7dW69G1L9btf+Bv9z//zD3rtl3eMWUuw05WdOEN+eTzWCuBYFaWepGgcW0+muM6R0dDQoK997Wu65JJLdOONN0qSWltb+76WlJ1cAOLNOqdCIL24wWrFukCtHWGvKGGOa/1qYx4WtrXmJL01F2Qgyy6+TNdc90ndevNX9Lkv/X3f48sfvU/LLr5MTz963ylfY6w4J23Zl1dTW6CzZpTK92inBUQdsUWyYwuSIkBMBdbJWmn5q4GeW2dVCMJeEU7q+NZZUiQqRXp94tqrT3hs+UvFCo+lixec9Hv/5Ud367X77zjh8bkz6vXMj2/Rub/7CS1/afUxSZOo8sqrVDprkZxzlLYDMeOc06IZpWEvY9BG6jjziU98Qg0NDbrzzjv7/fqXv/zl0/4ZADBcgXVyTnr2Davn1gbq6gl7RQl1XEV6mgqe/+Lrt+iBu2/XA3ff3vfYhe94rzatXyNJp5xbMtYa24pD2M+aXqpxVf3EiAAigdgi+bEFSREgZnoPdDv2O937XEG5trBXhEHx+0uKRDtaWbNhs84/64yTVnjkWttO+vW66ip96eMfGdLQ9tB4vsrnL5UMvX6BOIrb53ak1vv444+PyOsAwEiy1snzjNbtsHpkZaBce9grSjYTw0qRaTPmas+u7f1+reVIy6tpM+YM6rWuue6TJzzW21brzCUXDGt9o6mnIL22o1szJmQ0b0pWUvyuY4Cki9tnkthi6EiKADESWKcgkB58uaCVm6J9Qx3HMhGvFOnPfY8/q29+4RMnfU5ddZVyrafOzM2ZPnWkljVqSmeeJVNaEbuLHwAAgKjo3cB1IOf0wAsF7TgQ7evdxDgqKeKci8XMigWLzz/JkPTtkqSFi5cO+/U3rVuthYvPV3VN3bBfY7TtOlxQW5fVkpml8minBQBjikHrQAz0XtRu2+f07fvzJETiqJ9KkSgEK/c/8axmXXZdv4/X1VT121breHOn1590mPpTL67WpW8bfkAzFjLj61UyaSYJEQAAgGGy1qmzW7rvuYL+/QESImPqhNmFIa1jCJZdfFlf8uN4exq26sJ3vPe0Xv+pR+7VNdd96rReYyzk2q1Wbe1Sdz4eySwASAqSIkDEBdYpXygGFz94tKBmSs/jqd9KkfCTW03NrVq66NiZIWs2bNbXbrldv/y3fzjh+R/76/+rcz94bPXID//pb/T1f7v9hMRIrrVNf/YP39Gff+y6SA9ZN6UVKpu9hCAEAABgGALrFFin59ZafesXeb3ypo3FTfkkMcfPFInBv/+l779WLS1N2tOw7YSvPf3o/brmI6dOaCx/9D799iXT+328pmZcv221oqizx2nVli7l2i0xCQCMEdpnARHVW3q+da/T/c8V1NwR9opwOozfz+E2Ahe8n7j2ajW3tetrt3xfza3tampp1ZzpU/XMj28ZMJFx/ON11VV65se36Gu3fF/3P/HsMV/75vWfjHRCRMaofP75kudRJQIAADAEvXNDNu1yeujlghpbw15Rih3dPkuRCDMkSW0tzX3zQY5XXVOnL3/j33Trv3xV37z5J32PL3/0PtXPmKNLr/zQMc//+pf+WG+uW6OfPvxG32OtzU0687gWW5vWrdZ3b/6qbrrtgRH8TUZfwUqv7+jW/Pqspo/Phr0cAEg8kiJABAXWyTnpVy8UtPLN8KsJMAIiWikiSX/+sRPbZw3kR//0twN+7Ybro1+efrzS6QvllVeTEAEAABik3p3sh1udfvVCQVv2RuQOfJodfS3riomRsPzs9pu14Y1V2rtrm/Yc+d9ffPq3VVVTp/de9XvHJDsuvfJDqqqu1a03f0XTZs5TW2tOkvSt7/2q39euqqk95u/XXPdJtbXmdOvNX1FbazEBM23GHN16128iPUtkIE7SoZZA08YVb9URowDA6CEpAkSMtU5NrdJPnyroQI4AIzEiOlMkzfzaSSqZOjfsZQAAAMSGtU49BemxVYFe3mhj0aYpDcxRlSIykg0xzviDT35pSM9fdvFlWnbxZad83tHVJKfz86KsotRoycxSSSREAGC0kRQBIqK3XdbqLVa/ejFQvhD2ijCSju/zKyk6de0pZLKlKp97bt/nbiiG8z0AAABx1nv9s3GX033PFdTRHfaKcIzjK0UIM2In60vnzC6V55EQAYCxQFIEiIDAOlkr/XJFQWu2RqOlEkZYP5UiUWmflUZl886TfH9YCZGWDquaimKSi4AFAAAkXXGQerG176rNXL9G0nHXpCRF4sUzxYRIScbII74AgDFBUgQImXVOh5qdfra8oEPNYa8Go6bfmSJEK2EoqZ8vv2rckBMa1jm1d1m9ur1bNRWeFs8sVcZ3BC4AACCxnHPafcjp7mcKamoLezUY0NHXo0a0NYuZs2aUqKrMY8MVAIwhkiJASHpL0FdusnrwpUCFIOwVYTSZ45IijiqRUPhV41Qy7YxhVYhYK61r6JGT1NxhtXJzpxbNKFVdJQEMAABIFnvkrvrjqwM9+4ZlL0/EHTNTRMwujJO5k7OaWD30CnYAwOkhKQKEwFonJ+m+3xS0Zgs3x1Ph+PZZBCpjzmSyKpt//vC+1xht3NOtrvxb/93ygfTajm7NnpTR7EnZvucBAADEmXVOja3SnU8XtLeRa9bI6+f6k0qReJha52vWkTgCADC2SIoAYyywTt090o+fKKjhIFerqXF8+yySImOubM65MpnssKpE9jYVdKil/3KuHQcLautyWjSjREa00wIAAPFkrZPnGb2w3urRV6hkj43jqkSMCDXiYFylp4XTSvo6SAAAxhZJEWAMWVucH/Kjxwtqbg97NRhLhkqRUGUnz1ambtKQv886p85upy378id93uHWQGu2demcWWXKZEiMAACAeLHWqaNbuufZvDbv4To1Vvq57iTUiLaKUqMls0olUWkOAGEhKQKMEeecNjQ43fNsQT2FsFeDMXfCTBEilbHiVdSodOaZQ/4+55zkpHW7ugfVgqCty+mVrV06Z3apKksJcICxFredlnFbL4Bk6j0Wrdtp9csVgTp7wl4Rhur4eSIS7bOiLOtL584ulTHEC0CUxe1aPW7rjQKSIsAo6z0wLX/V6sk1gbg+TSnaZ4XD81U+f+mwvtUYo017utXRPfj/Vj0Fp9Vbu7RoRokmMDARGFPGGHVufVW2K/qlmF5ZpcrnnRf2MgCkXGCdgkD65fMFvbqVOYexddz1pjGGDVgR5RnpnNmlymYMleVAxBFbJB9JEWAUWetknfSL3xT0+jYCjTQ7oX2WeD+MhbLZZ8uUlA1rjsjBlkD7ckNvpm2dtLahR/OmZDVzYpYdG8AYsl3tsh0tYS8jFC0tLbr11ltVV1enXC6ndevW6ZJLLtFnPvOZsJcGIIKsdcq1ST96PK/D6TxsJgeVIrFx1owSVZV5xAZATBBbJDu2ICkCjBJrnXoK0g8eK2gXA9XhH3e4JVIZdZkJ05WdUD/k77POqSfvtGnP6fWP2Lo/r44eq4X1DFAEMLpaWlp000036YYbbjjmscsvv1yvv/66vvOd74S4OgBR45zT5j1Odz5dUPfJx6YhDvpJilAoEj1zp2Q1kUpyADGQltjixLMngNMWWKf2bunWX+dJiKDI848pY3eOSpHR5JVVqmz24mG3Dljb0KNgBP4T7WsK9NqObgW2mGwBgNHw0EMP6c4779SKFSv6HqupqdHFF1+sRx55RA0NDSGuDkBU9F4XPf2a1Y+fICGSFP3dZOeyM1rqx/maNTFLQgRALKQltiApAoywwDo1t0u3/iqvg81hrwZRYTz/2OiESGX0GE9l85dKxgwr8Ni2P6+2rpFLWuXarVZt7VJP3pEYATAqzj77bNXU1JzweF1dnaTizi4A6RZYp8BKP19e0OOrAy5Fk8Trr30W/4GjYlylpwVHKscBIA7SElvQPgsYQdY6Hcw53fFoQe1dYa8GkeJ7ko5OilApMlpKZ54lr6xyWHNEGtusdh0ujPiaOnucVm3t0nlzylReKgYrAhhRS5Ys0csvv3zC4ytWrNDMmTO1ZMmSEFYFICoC69TeKf3oiYL2NXJjNnGoFImsilKjJbNKJfVf0QMAUZSW2IKkCDBCrHXaedDpx49Tio5+eP6xOREilVGRqZuiksmzhvx9zjnlA2nj7u5RWFVRPpDWbC8mRipIjAAYZQ8//LCam5v1gx/8IOylAAiRtU77m5x+9HhBbZ1hrwajwTBTJJKyGenc2aXyzMAJkSBw8jwSJgCiL4mxBUkRYAQ457Rpt9PPlxdUCMJeDaLI+L6oFBldpqRcZXPPGfZQ83UN3cqP8ue3EEivbuvSuXNKVVXmEQABGFENDQ16+OGH9frrr6u1tVVPPPFEv6XvANLBOaeNu5zueqag/MgXwiIq+rmeJNIIl2ekc2aVKpsZuJ2vtU49gVRiJOOcPI+4AEC0JD22ICkCnCbnnNZssbrvuUCWHTkYiOcf+3dLqDKijFH5/PMkb+iJBuecdhwsqLljbP6bFKz06vZunTu7VNXlJEYAjJyZM2fqM5/5jFpaWnTnnXfq2muv1be//e3ElLgDGJoV66weXsn8kDgoK5Gqy6XqCqOacqOqCqmmwvQ9lvX7HR1S/N65557w2PwpWbV3O/UUjvwvX/yz+8jfeU+MrkUzSk66Aco5J+ukHz5WUIkv/dHlGWVFYgRAtCQ9tiApApyG3oTIvb8JxHVlepRmpeqKQT7ZeMouPLdYJHJUabtXWqGSaWfI9XTL5rvk8t1H/tcj8W4aspJpC+RV1A45wWCdU2uH1Y6DY9vzLrDSazu6dc7sUtWQGAEwwmpqavSZz3xGDQ0Nuvbaa/X4449r5syZYS8LwBiwzslI+tWLgV7cwCacqPA9aXKd0fQJRpPHGdVUGNVWSDWVRpVlUsY/9lowsE5yxSKQk90oN8bIlJSd8Hh1uaeq8iPP0YntmQpBMTnSlS8mTLryTm1dVq2dVj0FYpHTMW9KVhOq/ZNe3xtjdPczee06WPy3/u6vC/r4+zOqKHXySYwAiJikxhYkRYBhcs7p9e1W9z5HQiRJshmpfrzR+Kpjd2jVVhaDl6ryE4OWkzJG/qRpR5Iixe9zzsmUlqtk6jzJHFtS7ZyTC/JyPd1yPV3HJExsT5dsZ6tcT9cI/9bx5tdMUGn9vCF/n3NO1krrdvWMwqpOLbDSa9uLiZHaChIjAEbeVVddpTvvvFM33nijvvOd74S9HACjzFqnwEo/X17Qxl1EKGE5OgEybaLRzInFRIjvGTlX/G/knSLZcbo3xo0xOtkrZHyjjG9UUVpMpElvzbvLF5xaO4sJklYSJUNSPy6jmROzp3zeIysLWrvjrX/T/Tmn/3wgr49fmdHEmpO/NwAgLEmLLUiKAMNgndP6nU73PEM5epyVHEmATJtQ/N/MSUbja0xfQDDYHVonU7zRbXR0VNJ387ufm+DGGJlMiZQpkSuvkt/7BjsqeeIKeQXtzQo6mmXbWxR0tMj1pHNypsmUqHzeecOaI2KM0fpdXaEGedZJr+/o1tmzSlVXSWIEwPBce+21qq2t1R133HHM47W1tZKkdevWhbEsAGOoNyHyw8cK2r6fAGWsGCNNHTdwAsRayT9qQ5UxRhn/JC8YAu+4689sxmhclae6Ku/ERMmRJElrZ6Ae5tQcY1yVpwX1J0+IOOf0yptWz75xYhVXS4d0668L+uPLM5o95cT/LgAwVtISW5AUAYbIOqc3dznd9XSBGSIx0l8CZEJNMdFgXbGv7vE7ssIuXTbG9J84yWTl10yQXz1e5khz4bQmSsrmnSf5mWHNEdndWFBjW/htJayTXt/ZrbNnlmpcFYkRAEO3du3afkvYm5ubJUmLFy8e6yUBGEO9CZEfPFrQjgMEKKOtJCPNn2a0aKanRbM8lZcOnADxI5YAGazjK036S5S0dgY63BroUGug9q50v+8qS42WzCw96XOsddq23+m/nw8GfE53vvg5/uh7MjprFokRAOFIS2xBUgQYAmudtux1+ulTBQXh30vFSRgjzZhodNZMT4tmGU2qHTgB4pljKzni4PiEyUCJkkLLIRVyB1RoPiQFYzs3Y7SVTJ1X/H2HMUeko9tp6/7o/Hs4J73R0K0lM0s0vurkPYgB4HiXXHKJvv3tb5/w+HPPPSdJuvrqq8d6SQDGCAmRsVFdIZ01o5gEmV9v5PtGgX1r/kOcEyCDdXyipKrMU1WZpzmTS9SdtzrUUkyS5DpsqroplGSkc2aXyjMnzm7pFVinxlannz556o2VgZXufLqgP3hvRgtnkBgBMPbSEluQFAEGyVqn7fud/utJEiJRlc1I8+uP7Nqa7amitBisHH2BGscEyGD1lyjJ1E1Rdnx9sX9xW1MxQZI7INfdEeJKT59XWaeS6QuGVSHinLS2oTtywVpxXT06lxkjwLB5ZZVhL2FQRnqdN9xwg77yla/o7//+71VTUyNJamho0Pe+9z199KMf1VVXXTWiPw9ANFjrVLDSD0mIjIqp440WzTRaPMtT/QSv7zqyt61u2FXlYTv6WrU066l+vNH0CVkF1ulwazFB0tgWqDBwYUTseUY6Z1apshkz4LW7tU7dPcXWdt2D3JMVWOlnTxX0R5dldMY0ZowAYSG2SHZsYZyL2m0hIHqsddp1yOmORwvK0zs1UqrLpTNnvrVrK3Pcri28pfdwb4yR7WpXvmm/guYDCtpy4S5sqPysKpf8lky2dFiJg/W7unWgObrRme9JS+eWqbzUsDMMkdLV1aVt27Zp7ty5KisrC3s5JxjObKEwjfR6W1padNNNN6m6ulqtra1qaGiITdAS9fcWEEW9CZEfPFrQThIiI2ZyndGyhZ7OmeOpusLIWidzkgoA9M86J88U24q1dFjtbw50oDl5mwuXzCzRhOqBq7ztkbZqtz1U0O5DQ/+cZnzpTy7PaO5UQ2IEiRP16z9ii+THFiRFgFMIrFNji9OtDxbU1RP2aiBJk2qlJbM9LZ7taVo/u7YwOM5ZGeMV22zl9r/VZstFO1opm79UmbpJMsYb0vc557QvF2jTnuh/kEsyRhfMK+46IzGCqIh64IL44r0FDA0JkZHle9Li2Z7escjT7MkeG6xGWO8tJ+ukfU0F7WkqqKM7/u/beVOymjHh1LMNf/pUXut2DP/3zfrSx96X0ezJJEaQLFz/YbQM9r1F+yzgJALr1NFdDDhIiITr+GDFWtfXBssY0988cpxCb1LBZLLKjJ+m7MQZcoW8eg42KH+wIZKD2rOTZio7bsqQv886p64ep8174/FB7ik4vbajW0vnlsl48dqhAgAARk9vQuSORwpqOBj/G8thqq2ULlro621neqooK1aFSLTFGmm917G+kerHZzR9QlbN7YF2NxZ0qDWIXEvbwZg2LqOZE7OnfN7DLxdOKyEiSflA+tHjBX38yoxmTmQjIACMFJIiwACsdSoE0g8eKag53uMXYm2gYIWLwZHVO5zdZLIqmTpHJVPnKmg+pJ6DOxQ0Hwp5dUVeebVKZy4acllo7+60dQ3dpxxsGCUd3U5v7OzWuXNKpZiV7gIAgJHXG5/c8SgJkeEykuZPM3r7Wb7OnGmko6rNiS9GX28FdE2Fp9rKUuULTnuaCtrbWFB3IR7v6fFVns6oP3lCxDmnlZusfrN2ZCrw84Xi7KBPvD+j6RN4rwLASCApAvTDOScn6SdPFLQ/F4+LsyQhWAlXbwWJXztBFXWTZLs7lT+4U/lDu+QKg5wOONI8X+Xzz5eG0dPZGKM39/SoPYZl+s0dVht29WjRjJKwlwIAAEJEQuT0lJdIS8/wdPEiX+OqizMIPWP6Ks8xtnqv57MZo1kTM5o1MaPDrYH2NBbU1B7dVr6VpUaLZ5ae9DnWOm3d5/TACyM7w7CnUOxg8cn3Z1Q/nrgYAE4XSRGgH8YY3f+bgrbtI+AYSwQr0dLXXqukTCXTF6pk2gIVGveq5+BO2fbmMV1L2axFMqUVQ06IOOd0qDXQ3qbCKK1s9B1sCVSyL68z6kmMAACQRiREhq+8RHr3Ob4uXuzJ96Tefz1aZEVH7/X9+GpfE2sy6ui22ro/r8OtI5tUOF0lGaNzZpfKO8kmrd55pD97qjAqFerd+eJx4FNXZTS5jvcxAJwOkiJAP55aE2j1lujuUEmaibXSu872dd48T573Vg6Ei7xo6LvoN0aZCfXKTpyuoKNFPfu3q3B4r94KL0dHZny9shNnDPn7nHPqKTht2h2POSIns7uxoNKsGdQwRwAAkBzWFWeI3P5oQbtIiAxaNiNdvMjTe871lfXf2lXPVVR09bbWKi8xOntWqVo6Am3dn1dzR/hxuedJ58wuVTZjBrwWt9apq0f64WMFdY9icX1Xj3T7IwV9+qqMJtYSMwPAcJEUAY5indMb26yeWBOtXSlJVVMhXXa+rwsXeLKOC7o46K0e8cqrVT73XNn6+eretVGF3IHR+XmlFSqbc/aQ54j0WtfQo0L4cdSI2Lo/r9Ks0aQan8QIAAApYST9/CkSIoPlGenChZ6uWOqronTobVcRvt7/ZlXlns6fW6bG1kBbD/SovSu8z8DiGSWqLD1JQsQ5WSf96LGCcu2jv57Obun7Dxf0maszGl9NHA0Aw0FSBDgisE4Hck73PkdCZLQdXcZujpQf+1zHxUpvQGBKy1V+xgUK2nPqbtiooK1pJH/IkTkiAwcgA3HOaduBvFo6E5IROWLD7h6VZktVXe717aYDAADJ9eBLgTbtJiFyKkbSkjme3n+hr7qqYh0zCZF4673WravytKy6XPtzBW0/kFdXfmw/D/OnZjW+6uSbkoykO58uaPfhsVtbR7f0vYcK+l+/nVV1hSMxAgBDRFIEULHUNV+Q/uvJggrkREZN1pcuXnxiGTviq69ypKJGFWe9XYXmQ+retVG2s/W0X7t0xpnyyquHlRDJtVs1HIrvHJGBOFesflk2v0zGH171DAAAiD7nnF7eaPX8+mRt8BgN8+uNrrrIV/14T9YWr4+4QkqO3uTIpFpfk2p97W0saMfBvPJjELdPG5/RjAnZUz7v4ZWB1u8c++Rle5f048cL+txvZ+QZYgMAGAqSIoAkY6SfLy8o1xb2SpKpt4z98vN9VZaxayuJepMjfs14VS75LeUP71H3njflujuH9Xp+7SSVTJkz5O9zrjiIdP2u7mH93DjoKTitbejWeXNKw14KAAAYBdY6bd/v9KsX2a11MtMmGF21zNe8ek/BkanWbLpKrt7kyLTxGU0dl9GuQwU1HM4rGKW84fgqT2dMPXlCpDd5+dza8JKX+3NOdz1d0B9ffurkDQDgLSRFAEmPrwq0eQ9l6SOtt4z9ygt9jaOMPRV6kyOZ8VOVGV+v/MGd6tmzRa4w+GHnJlum8rnnDn+OyK7uMdk5FqbmDqttB/KaN6Uk7KUAAIARFFinXJv006cKsoQn/cr60hUX+Lpksdf3b0TroPTobb08a1JGU8f52ri7R03tI5uUqCwzWjzz5BuQrHXaujcaycsNDU6PrSrofRdwiw8ABosjJlLNWqeNu5yeeZ2y9JE2Y6LR717sq34CZexp1JscyU6aqezEGerZu1U9+7YW+z+d/DtVNv88yR/6MHHnnBoOFZQb4aAoqhoOFVRT4WnCKXocAwCAeOht6fvDx/LqGvx+klSZPdnow+/KqLaKuYRpZ4xRSUY6d06Z9jYVtGVfz4hUjZRkjM6dVdY3+7I/gXU63OL0s+XRSV4+/ZrV1HGBlsz2qJgCgEEgKYLUCqxTc7t0z7MFReQ6JhEyvnTZ+b7edfZbO7e4KEsvYzzJSCXTzlBm/FR1bX3tpPNGSqbNl19ZN+Sb/NY5tXVabT+QP90lx8qGXcX5IqVZqrAAAIgz55ycpJ88UVDj6Y9mS5yjq0Oce6uVEtKt9/p3ap2v8VVlp1014nnSObNLlckM/B6z1qmrR/rhYwV1Ryz0uPc3gSbVGk2qo3oKAE7FC3sBQBicc7K2GHRE7UImzmZMNPrC72T1zrO94s4tLsRwhDFGXlmlKhZfopJpZxQH+RzHrx6vkvr5w6oQsVZat6sndQnOwEprG7rlVPx3AAAA8WSM0S9XBNq+n/P58WZPNvriB7O6eHExxmDDFY5XrBoxOndOmRZOK5E/zDtdi2eUqrLUDJgQcc4psMWESHP7aSx4lOSD4uD17p5i8gYAMDCSIkglY4zuey7QgRwXCiMh40tXXujrc/8jo3HV7NxC/4wpBrIl9fNVsfgSeeXVb30tU6KyeedJw0hrGGO0cXePuvPp/Dy3dTm9uaeHShGknrPxap0Xt/UCGD3OOT37eqBVmzkuHC3rSx+4yNenP5BRbSUxBk7u6KqRi84o07jKod3umj81q/FV3imvqe98uqA9h6MbdzR3SD9+osCmKeA0xe1aPW7rjQLaZyF1rHV6davVa9s4YIyEGROLfX3H19DXF4NzdNVIz94t6tm7RWVzz5HJZPtmkQyWc057mgo61Br+gMMw7csFqqkoaGod80WQXsbz1H7/7QoO7wt7KafkT5iqyg9+MuxlAIgAa5027XZ6dFW6r2WOd/zsEC5vMFjDmTUyfXxGMyZkT/naD70caEND9BMNDQedfrki0LXv5JYfMFzEFsnHERKpYq1Ta6f0qxcJOk7X8bND2LmFoehNfpTUz1d24kx5JaVDfg3rnDq7nbbsoweeJG3e26Pq8jJVlPJ5RHoFh/cp2NcQ9jIi49prr9W9994b9jIADCCwToeane56uiA2dBf5XrECndkhOB3HzxrZsLtHuQFmjUyo8jV/6skTIs45vbTBasW6+GysXLXZasq4QJcsPnX1C4D+EVscK2mxBe2zkCrGSHc9zRyR08XsEIwUY4xMtmTI3+eck3NH5mlwE0GSZJ20dmfx34NSeQBf+9rXtHbt2rCXAWAA1jl156UfPVZQTyHs1URDVbn06Q9kmB2CEdM3a2R2qWZMOHFPcFWZ0aKZJ49FrHXavMfp1y/Fb2PlIysDbd3rmC8C4LQlMbYgKYLUcM7pmdetdhzggmC4jKTLz2d2CEbWcHYuGWP05t4edfbweT5aV75YOcNuMCDd1q5dqzfeeCPsZQA4Cc8Y/eLZgpo7wl5JNEybYPT5a7KaNmHgIdfAcBTbrxnNn1qiM6eX9LViK8kYnTO7TMYMHI8E1ulgs9PPlxcUx7yCddLPlheUay/+LgAwHEmNLUiKIBUC67SvyenJNfHb3REVpVnpjy7P6NLzqA5BuJxz2p8raH+Oz3N/9jYVlGsPZKkWAVLrwQcf1Ac+8IGwlwFgANY6vbQx0MZdnKsl6Zy5nj57dUaVZSLGwKiaUuvr/LmlKiuRzp1dqow/8EY/a506u4vVXHHuNNHVI/348TzV9QCGLamxBUkRJF5vm527ni6ccsAa+je+Wvp/fjujhdMNO9ARKuecuvJOb+7tCXspkbZxdw9ttICUuu222/S5z30u7GUAGIC1Trn24sDmtDOS3neBr4++JyPPE+2yMOqMMaoq83TR/HJVlA5cleScU2ClHz6WjGqug83FVloAMFRJji1IiiDxjDF66OVAB5vDXkk8zas3+tNrshpfTV9fhM9JWtfQTYLzFLryTltpowWkztq1azVz5kzV1NSEvRQAAzHSncsLyqd8jkhvFfq7zynekqBlFsaKZ8xJW2b1uvPpgvY2JmeD0Qvrrbbts7TRAjBoSY8tSIog0QLrtGWP1YsbuIM6HO84y9PHr8yoJEMpO6Jh67682rq4kB+MPbTRAlLnwQcf1FVXXRX2MgAMwDmnJ1cH2n043edmqtARtlO97x58KdCGhmR9Tp2kXzxbUBBQTQ5gcJIeW5AUQaI5J92/IuXbsIbB96QPXuLrt9+RkWeoEEH4nHPKtRe0u5HP81DQRgtIjySXtgNJEFinXYecnnk93Zu1qEJHlDnn9ML6QM+vT+bnNNcu/erFgGQkgFNKQ2xBUgSJ5VxxsHpTW9griZfKMulTV2V0wQIOD4iWmnJfk2r8sJcRK115p637aaMFJF3SS9uBuOudT3DX0wWluXPNRWdShY7ocs5p2z6nB19K9uyNVZutNjTQRgvAwNISW3DXE4lkrdPBZqffvJHMHR6jZep4o8//TlbTJw48dA4IgznS+3fxzFLNmZwNezmxsqexoGbaaAGJlvTSdiDujDF64IV0b9Z65xJPv3sxVeiItkm1RuOqwl7F6LvvuYJ68iI+ANCvtMQWmbAXAIwGzzO677l078QaqjNnGP3+pRl5Hju3EE291Q6zJmZUWWq0blexNRRObcPuHi07o0xOjqoRIGEefvhhrVu3Tl/72teOefyNN96QpL7Hv/zlLyd+txcQRdY6rW9wWr05vZu1Lj3X0xUXcOsB0WaMUUWZ02euzur7D+d1sDnsFY2e9i7pvhUF/eF72WwG4Fhpii24MkHiWOu08k2rhoPcLR2sJbONPvqejGREhQgizxijCdW+zplVqjd2dpP8HITeNloL6kvCXgqAEXbVVVf1u5Pra1/7mtauXasbbrghhFUBkIpxSUd3umccvu8CX+85l/aniAffMyovLSZGbn+4oH1NyQ001u1wenVLoHPmelRvAeiTptiC9llIFOecOnukR19Jdh/QkXTePE+/fykJEcSLMUZ1lZ7OmV0qjzPZoOxpLKityzJ0HQCAMeJ5Rvc8W1Bnd9grCccHLiIhgvjxPaOyrPTpD2Q0bUKy4+MHXgzU3l1M4AJA2lApgkQxxuhXLxbU1RP2SuLhwgWePnhJMVAhIYK4McaotsLTebNL9dqObgXp7UoxaJv39uj8uWVhLwMYNf6EqWEvYVDGYp25XG7UfwaAgVnn9MJ6q8170nmz8aplvn5rCQkRxJPnGZVknD71/oy+93BBexuT+Tnu6pF+8WxBH7+SNlpAf4gt3pLE2IKkCBIjsE7b9zm9vo07o4PxtjM9/c7FGTnHjAHElzFG1eWezptTTIwUKBI7qeYOq4MtBU2o9kmEInGctar84CfDXsagOWtlRqHU7c4779Rzzz2nRx55RJJ07bXX6uyzz05UqTsQddY6NXekt3r9iqW+3nk2CRHEm+cZZTJOn3x/Rrc9VNCBXDITI5v3OL24IdBFC2mjBRyN2KIoybGFcfTRQEI453TLL5N7sTKSLlro6XcvISeK5LDOqb3L6tXtVIycSlnW6KIFZSRFMGRdXV3atm2b5s6dq7IyKo4wcnhvIYl++Fheb+5OX1zCUHUkTWCdunqk7z6Y1+GWsFczOrIZ6YsfzKq2QiRGMGa4/sNoGex7i07sSARrnVZusiREBmHpfBIiSB7PGFWVeTqXGSOn1JV32nW4wGwRAABGQWCd1u+0qUyI/NYSEiJIHt8zKiuRPn1VVuOqwl7N6MgXpPt+UyAhAiBVuHWERAis9MSadJanD8U5cz1d+06fm6FIpN5WWufMKhXX8ye382BehUAcCwAAGGHOSb9+qRD2MsbchQs8feAiEiJIJt8zqiiTPv2BrCoTuqF96z6ntTusAoauA0gJkiKIPeucnnk9UFtn2CuJtkWzjK57ty8nMUMEidU7fP3sWaXibT6wwErbDvRwLAAAYAQ557T81UC5trBXMrbmTDH63YvZeIVk8z2jqnLpjy/PyE/onbSHXi6IjzGAtEjooRxp4ZxTR5f0m7UMETiZ+fVGv39pcecWcwSQdMYY1VV6WjyjJOylRNrepkDtXZYbGAAAjABrnXLt6YtL6iqlP7qsGGew2QJJ53tG0ycaXfMOP+yljIpcm/Ts61aW+ABACpAUQawZY/TYqkD59FWoD9r4aukP3puREQkRpIcxRhOqfc2dnA17KZG2eR/VIgAAjATPM3rg+YIKKeroW5KR/uSKjEqyDGdGenjGaNlCX+84K5m30555I1B7p0iMAEi8ZB7FkQrWOh3IWa3anK7dWENRmpU+dkVW2QyBCtLHGKNZk7KaVJPMnVwjIddudai1QNADAMBpCKzTm7utNqVouLqR9HvvzGhSrZFPnIEUuvrtvubXJ++9ny9Iv34pYEMlgMQjKYLY8jyjh14O6Hk5AGOkj7wno/HVIlBBajnndNb0ElWV8RkYyNZ9efGvAwDA8BkjPZiy4eqXnudpyRyPjVdIL1fsyDC+OuyFjLw3tlvt2M/QdQDJRlIEsWSt084DVm+maDfWUF2x1NfC6YZABalmjJGMdM6sMmUzYa8mmjp7nPY2FZgtgkHjvYKRxnsKcWat08qNVgebw17J2Fk8y+jypVxYId08zyibKXZmKE1gx94HXwrYXIkxwXUgRtpg31MkRRBLnmf05JoUNewdonPnenrPuT6zAgAV+/5mMtLZM0vFR6J/DYfStbsVw+P7xVZ0+Xw+5JUgabq7uyVJmQw3WRE/hUB6IkVxydRxRte9O0PrTUDFjgzjq6WPvDuTuDhj92Gn17cFVItg1BBbYLQMNrYgKYLYsdZp9yGrzXs4Ofdn2gSja9/pE6gAR/GMUXW5p4X1JWEvJZK68k4HmgOOGzipbDar0tJSNTc3s6MLIyYIAjU2NqqyspKkCGLHOaflrwVq7wp7JWOjorQ4WN3zxLwB4AjPM1o4w+iKpcmbY/jYqvQkfDH2iC0wGoYSWxB5IHaKVSLsau5PVfmRQMUQqADHM8Zo6riM2rqsdjdyDDnezkN5TanjsgAnN3HiRO3evVu7du1SbW2tstksVYkYMuecgiBQZ2enmpubZa1VfX192MsChsQ6p9YOacU6G/ZSxoRnpD+8LKOqcuYVAsczxug95/ra3+T02rbkHBMaW6UXN1i94yzmB2F0EFtgJAw3tuDuB2LFWqeDzU4bd5FFPl7Gl/748owqSsUFC3AS86dm1dFt1dSenIBlJHR0Ox1qKWh8tU9SFQOqqamRJB06dEi7d+8OeTWIO9/3VVFRocmTJ6ukhEo+xItnjB59paBCSjZSv/c8X7MnG25WAQOwzulDv+Wr4aBVU1vYqxk5y18NtGyBpxL6zGAUEFtgJA01tiApglihSmRgv3Oxr2kTDDczgUFYPLNUq7Z2qbOHBOvRdhwsaGINlwY4uZqaGtXU1CifzysIUnI3ECPO8zx2AyK2nHPKtSlRO8JPpn680XvO8/i8AifhGSPnOV37zoxuf7igpEQZHd3S068FuuICZpZidBBbYCQMJ7bgzgdiwzqnxhZp3Y6kXF6MnAsXeLrgjOT1MAVGgzFGnue0ZGapXtnaJdqXvqWty6qpLVBtpUeCFaeUzWaVzWbDXgYAhOLp14JUXEP4nvThd/nF35VLA+CkfM9o7lSji8709NLG5CRNV6yzumSJr4pSR2IEo4bYAmONAjjEhmeMnno1SMyOi5FSWyn9j7f5DKYChsAzRhWlRrMncdF1vB0H8yREAAAYgHNO7V3S6i3JueF5Mpee62tynWGOCDBIzjl94CJf46rCXsnIyQfSc2u5FwMgWUiKIBaKJepOr6ekRH0orv2tjHxf7NgAhsgYo1kTM6oq47NztOYOq+aOgEQrAAAD+M0bgYIUhCW0zQKGrliVLl37zkyiiqte2mhFZyMASUJSBLHx3NpAlnt0x7hwgaf50zx2bgHD5CSdNb1UxPrH2nkwzw0QAAD60VOQXt6U/IzIMW2zAAxJsY2Wp4vOTM4tt66e4rHPclMGQEIk5wiNRCsE6SlRHyzaZgGnjzZa/Wtss2rrshxfAAA4irVOz6+z6s6HvZLRR9ss4PQksY3WinUBs4UAJAZJEUReYJ1Wbbbq6gl7JdFC2yxgZNBGq39UiwAAcCzrpOfXJ79/DG2zgNOXxDZauTZp7XargGoRAAlAUgSR53tGL26gSuRotM0CRhZttE50qCVQT4GABwAAqbhRa+Umq/ausFcyumibBYycJLbRevYNy30IAImQnCMzEslap+37rA7kuCrvRdssYOTRRutETtLepgLHGgAAJBlTnHGYdLTNAkZW0tpo7TlcvEfDbBEAcUdSBJHmeSYVJepDQdssYHTQRutEexsLYS8BAIDQBdbp9W1WTW1hr2R0TaiR3nMubbOAkdTbRuuad2TCXsqIeeaNQB6JUwAxR1IEkeWcU2un0/qd7EDoRdssYHTRRutY3QWnw22BLNUiAIAU8z2jZ15Pfjvf913gizM+MPJ8z2jhDE9zpiQjyHhzl9OhZkeMACDWSIogspyTXlwfiKrMouoK2mYBo623jdasibTR6rW3sSCPLBEAIKUC67Rpl9X+pmRfg0+bYHT2HJ/NV8Aosdbp/cv8sJcxIpykZ98IEjNAHkA6kRRBpL28Kfk7sgbr8vN92mYBY6C3jVZJhs+aJDW2WXXnLQlZAEAq+Z7R068lv53vVct8BexGA0aN5xnNnOTprJnJiDFe3WrV0R32KgBg+EiKIJKsddq026m9K+yVRMPEWumCBbTNAsaKMdLsScnp+3u69jYxWwQAkD7WOu06aLXjQLKTBfPrjebVE2sAo623WiQJ+xwLgbRiHW12AcQXSRFEkucZrdlClUiv9y3NiGsNYOwYY1Q/LqPykgRELCNgXy75O2QBADieMcmvXDeiSgQYK55nNKnW0/nzk3Er7qUNVgFhAoCYSsaRGInTk3fa0JDsAGSwpk80WjKHnVvAWHOS5kxmtogkdeedcu200AIApEtgpTe2JzsmWTLHU/0EYg1grFjn9L6lvjIJGC/S2SO98qYlqQoglkiKIHIC6/T6NqsCOw4ksXMLCItnjCbXZlRVxk0CSdqXKzDTCACQGoF1Wr/Tqjsf9kpGj2ekKy/0ZYk1gDHjGaPqCultZybjdtyqzZakKoBYSsZRGInie0ZrtiZ7R9ZgnTHNaO5Udm4BYbHOad6UkrCXEQmHWgIVAm6aAADSwfeMVm9Odkxy4QJP46qKLX0AjK33nuerNAFF6XsOOzW2OirKAcQOSRFETmuH0/Z9nFB7+/uycwsIj2eMxlX5qqvkdGmddKCZYYoAgHTo6HLavCe557ysL12+1Fdyf0MguowxKi2R3rkkAT20JK3eHDADFUDscJcHkRJYp9VbLBfnks6e62nqeI+dW0DIitUiCdjGNQIOtxbk0UILAJBwvTFJkvcmXbzYU0WZOK8DIfGM0TvP9lRZFvZKTt9rWy33LQDEDkkRRIrvGb26Jdll6oPhGenKC3x2ZAMR4Bmj6nJfE2uSsZPrdDS1M0gRAJB8vme0OsExie9J7zrbJyEChMz3pHcsin+McbhV2nPY0kILQKyQFEFkOOd0oMlqf44T6bKFnuqq2LkFRIWjWkSS5Jx0uJUWWgCA5HLO6UDOal9jcs91Z8/xVF5KnAGEzfOM3namJz8Bd+bo+AEgbhJw6EVSOCe9vj25O7IGK0N/XyByjDEqL/E0tS7+O7lO16GWgIQtACCxnKRX3kx2TPKORR5zC4GIqCwzWjQr/rfmXt+W7OMmgOSJ/5EXieF5Rut3cnF+zhxPlWWGm45AxDjnNGMC1SKNbVSKAACS7bWtyb25N3W80cxJzC0EosJap4sXxf/WXFuntG2fI+EKIDbif+RFYjS3O+1r4gTKzi0gmowxqizzVFOR7lNnYKWmNnoGAwCSx1qnrXucWjvDXsnoefuZHvPBgAjxPKPZUzxNqYt/ovLVLVbs7QQQF+m+s4PICKzT2h3J3ZE1WNMmGE2fyM4tIKqsc5o2LhP2MkJ3qKUQ9hIAABhxXsIHrJeVSOfP9+QTawCRElint50V/9tza3dY2eQeQgEkTPyPukgE3zPasJOzJzu3gGjzjNGkWl/ZlI8WOdwahL0EAABGXE/BaV2CY5Lz53vKpPwaBogi3zNaeoan0ph36u3OSxsaHPc0AMQCSRFEQk/eaceBdJ84y0qk89i5BUSekVSf8mqRfCC1dNBCCwCQHIF1emObVT7BxZAXL/LFmRuIpqwvnTcv/rfoXt0acE8DQCzE/4iL2LPW6c3dTkFyN2UNygVnePL5RAKxMG18upMiknSwhWoRAEBy+J7RGwlu5ztvqtGEGiOPhv9AJDlJFy+O/w2BTbudevKkXwFEX/yPuIg9Y6SNu5IbgAyGkfQOdm4BsWCMUWnW04TqdPefONQayHBjBQCQEIF12rYvuVfjbz/Lp6UNEGHFNr2e5kyJ9/V1IZBe32453gCIPJIiCJ0xRpt2pzspMq/eaHw1O7eAuLDOpb5apDvv1N6V7mM3ACAZnHNqOOAS2zqrukJaNMvQ0gaIuMA6vT0JA9e3W443ACIv/kdbxN6BnFVbZ9irCNfbF7FzC4gTzxiNr/JVVpLui/2m9kCWuSIAgJhzTnozwZu0ls4n7AfiwPeMlsz2VF4S9kpOz/b9Tpb7GwAijqsjhCqwTlv3pvtkWVshnTWTnVtA3DjnNC3lA9ebOywVbgCA2PM8o817khuTLJntidM1EA+eZ7Rgerxv1fUUpN2HnRybpwBEWLyPtIg93zPavj/dJ8plZ/pimAgQP8YY1Y/LKM35zOZ2hq0DAOKvq8dpT2MyL8iryqXpEz3mgAExEVinRbPi/3ndvMeJYhEAUUZSBKHbvj+5peqDceECT16a76oCMZbxTaoHrucDqbMn3cdwAEC8Weu0eY9VUjc0nznDY7c2ECO+Z3TmDE9+zO/WbdvLXBEA0RbzwyzirrHVpXqeSP14o5oKLhSAuLLOpTopIkm5dstcEQBAbBkjbd6d3PPYolleYhM+QFKVZI3mTIn3fYKdB52CgIMPgOgiKYLQFOeJpHuH8VkzDQPIgBjzTLFSJN4hy+nJtQfMFQEAxJYxRpsTGpNkfemMaYaqdCBmAut01sx4364rBMXECJVqAKIq3kdZxJrvGW3bl+4T5GKGHgKxl/GNairSezpt7kjmjSQAQDo0tjrl2sJexeiYP80o4xNsAHHje0aLZ8c/vtiS4NaEAOIv/kdZxFqa54nUVEj14xl6CMSddU4TU9xCqzvv1J1P77EcABBfgXXatCu557CzZnoKqEoHYqm20mhKXbzvFWzZ66hUAxBZJEUQmpZ2p+b2sFcRnjNnMvQQSALPGE2sSW9SRGKuCAAgnnzPaPOeZCZFjIrzRBh0DMSTtU5nzYr353f3Iad8gRgBQDSRFEEorHXati+ZAchgLZrJ0EMgKcpKPFWUxDtoOR3NHTbVc1UAAPFUjEmSeUE+faJRZRlnZyC2jLR4Vrxv2Vknbd/nmKMKIJLifYRFrO1pTO+JsSRT7PFLKSmQDM45TUhxtUhze0ArQABArDjntPuwU3c+7JWMDlpnAfHmGaPpEz1VlYe9ktOzeW+6N8MCiC6SIgiF5xntTXFSZP40Qyk7kDBpnivS0eOUD9J7TAcAxI91SvQ8kcWzjQg3gHhzzumsGfG+bbeVuSIAIireR1fE2r4UJ0UWsXMLSBRjjKrLPWXTmxdRW6dlThIAIDZ8z2jHgWSetypKpcl1HlWcQMxZJ82rj/fneF+TU3c+mcdaAPFGUgShaO106ugOexXhMIahh0BSjU9xtUh7txXhDgAgTvYeTuaZa/pE4gwgCXzPaOakeN+2c07aspe5IgCiJ95HV8SSdU57DqX3hDhzklF5KYEKkDROKW+h1c2wdQBAfDS3O3X2hL2K0TFtguEGJJAQ46qNSrNhr+L0bN+X3FaFAOKLpAjGnHPpHrI+v97QOgtIIM8YjatKb1KkvcvRpgMAEAvWOu1K8Cat6RMI84EkmTYh3tfY+5qYKwIgerhawpjzPaO9jendKTB9osduaiChfM+ovCSdn/D27vQe1wEA8bPncHLPWzMmGW5AAglhrYt/UiTFm2IBRBdJEYQiqf17B2PGRIIUIMmqytJ5ag2s1FNI77EdABAfnmcSG49UlEo1FcQaQFI4xb9SpKO7WFUOAFGSzjs3CFVPwSnXFvYqwlFVLlWVx/uCBsDArHOqLk/vqbW9y8o5Ah4AQPQltZ0vQ9aBZPE9o1kxH7YuFTfGEicAiJL4H1kRO4dbnNJ6Koz7Dg8AJ2ekdCdFuq2IdQAAUdfe5dTWGfYqRgdD1oHkScKw9b2NTja5XQsBxFB679wgFNY6HWpO70X69AkMWQeSzBiT7qRIlxWz1gEAUeac076m5F6PM2QdSKa4b7Dc1+Tk+/H+HQAkC1dMGFPOSU0pbZ0lMWQdSIM0D1vv6HYyZEUAABEWWGl/gpMiDFkHkodh6wAw8kiKYEx5ntTYmt6TIUPWgXRI67D19m5q4gEA0eZ70sFcMuMRhqwDyZSEYeuHWpwsfXYBREg679ogNMaY1CZFGLIOpEOah60HVuopkBgBAESXMUYHEpoUiftNUwD98z2jmTEfth5YqaU97FUAwFvifVRFLDWlNClCkAKkQ9qHrXd0p/MYDwCIjwMJnXE4qc6wExtIqHFVUtybThzIOTmOUQAiIr13bRAKa52aU7o7gCHrQDqkfdh6d55gBwAQXR3dTp3dYa9idFSXG1kKNoFEMsaosjzsVZyeg81OAccoABGR3rs2CEVLh5TWvABD1oH0SPOw9Z6CEzkRAEAUOed0IMFD1msqJJPOyw8gFWpi3o77UIuTz11IABHB4QhjxjmnwyltnSUV22cxZB1Ij8qUDlvvKThuyAAAIsm64k7lpKqpMPKJN4DEqq4IewWn51CzkyFQABAR6bxjg1BYJ+VSmhQxkqrKwl4FgLHinFNpJp0X/MWkSDp/dwBAxDmptTPsRYye2krOv0BSOedUXRHvz/ihlnTeDwIQTSRFMHac1NYV9iLCUV4qqkSAFHFOKklxUgQAgCjyPKmtM7nnqaqYzxsAMDDrinOD4qy1Q8oTKwCICJIiGDPGSO1d6TwBxn1HB4AhMlJJNp2f+558Oo/zAIDoM8aoLaHxSMaXSlN67QGkgivODYq7ju6wVwAARSRFMGY8z6T2BJiEixcAg+cZk9r2Wd3s/gIARFh7QttnVVMlAiSa58W/UkSSOrqJFQBEA0kRjKmOhO7MOpUkXLwAGJq07tYMrGRtOo/1AIDoS2r7LCrTgWQzxqi2MuxVnL62hCamAcQPSRGMqfaUzhSpLpcCbhICqZLWmSKS1BNwvAMARFNSZxxSKQIkXxKSn+1djg1UACKBpAjGVFpLJasrjJTOXx1IrYxvZOIftwwLc0UAAFFUCJy682GvYnRUVxhZx/kXSLLyUsmLeXzR3lUcGg8AYSMpgjGV3koRI8OnDUidNM8VcdyYAQBETJJjkZoKI2fDXgWA0eQZo8qysFdxejq7XWo3jgGIFm7TYswUAqeeQtirCEdtVfECBkC6pLWFVk/eiZwIACBqkjpPRJIqSyWl87IDSJXKmM8rbe+Of7ULgGQgKYIx09UT9grCU5OA3p8Ahq4kxcPWuTEDAIgS55xaOsJexejxfU69QBr4Mf+gd3Q5GTaMAogAkiIYM0nt3zsYcS9xBTB0zrnUVopYJ+YoAQAixdpkV4qw8xpIBy/md/E6usNeAQAUxfxwijgJUjpNq7xU8olSgNRxLr0zRZxzbFcFAEROW4Jninie4dwLpEDcby0kebYTgHghKYIxUwjCXkE4SrNhrwBAWPyUnmUtOREAQMQYL+GVIh7nXiAN4h5fdHQn9zgMIF5ifjhFnKQ1KRL3nRwAhi+t7XJTWhgIAIgwz5hEJ0V8I/r0AykQ+/ZZVIoAiIiYH04RJ6lNivApA9IpxTcnnGOAIgAgepLctoWYA0iHuG+6tE7qzic3QQ0gPrh0wpjJpzQp4nNjEEittH78rQ17BQAAnCjJm7So0gTSIQmf9U6GrQOIAJIiGBPOuUQHISfDri0gvVKaE0lEsAYAQJxYW4y5ACRbEq6zmSsCIAq4XYsx4ZwUJOHsPQxxL28FMDxGKa4USefhHgAQcUk+PVmb7N8PQFESKrLzhbBXAAAkRTBGnKQgpZUihk8ZkFopzRZdq7EAAEiHSURBVImwUxUAEE0JPj0FziX69wNQFCQgKZLWjWMAooXbtRgzSTh5D0cSdnIAGJ603pugUgQAEEVJPj0RcwDpkITrbLppAIgCkiIYM2mdrUGAAqRXWgsmkhCsAQAQJ5ZCESAVkhBfUCkCIApSepsaY81IyqT03cbNQSCdnJIRtAxHWn9vAADC0tnN+RdIg84EDClP64ZZANHCoQhjwhjJ99O5HcCSFQHSKcU7Nn2uLgAAEZTkpEFrp6MlDZACrZ1hr+D0cagCEAXctsCYMMYo44e9inCQEwFSyqR34LhPTTwAAGOqtUPyyIoAidbV41QIwl7F6SNUABAFJEUwZrIpTYoECbhoATAMLr1JUUriAQBRlOTTcmtnkn87AJLUlpDPOflbAFHAbQuMmbRWirR3h70CAKEwUr6QjMBlqGifBQDA2GrtSOc1B5AmzR1hr2BkUCkCIAq4bYExk9akSCGQuvMEKUDaeMaoJ7VJEZPa1mEAgAhL8KkpCXMGAAwssE4t7ck4iBmyIgAigKQIxkxakyKS1EaQAqRSWpMinpfo+04AgJhK8rmpq0cqBEn+DYF0cy45yU9yIgCigKQIxkzGT++ZrzkhOzoADE13SpMiPo2CAQBRlPDTMhuxgOTyvOS0ySNUABAFJEUwZrKZsFcQnpYOpyCtE5eBFOtJaes831PibzwBAOIn6aemloTcMAVwIs+YxHzGqRQBEAUpvk2NsVZecurn/OLf/0DlleO09NLPqH7OUnV15LR32ytatfx7uuR//G/Vz1l60u9//sGbNHX2Us1dcvmg1tTVkdPq5d9TZ1tj398725sG9bOGorWjWO4KID2cc8oHYa8iHB6RDgAggpLezre53claJ49t2EAiJaUajFABQBSQFMGYyfhG2YyULwz8nO6OnDasvFern/5+32NlFXW69k9/esokRVdHTk/e/be69k9/Nqj1dHXktOJX/6xLfvt/q6yiru/x9S/fq9u/+Q794ZcfHHRy5VRaOh0lokDKpDUhIh2pFOGYBwCImMqysFcwulo7JetoBwEkVWtnMnZakhQBEAUkRTCmKsukXNvAX586e6kuvvrL2rdjtSSpbtI8Lbro2kG99url3xvSWta9dI9WP/19Lb3008ckRRZddK3KKur05N1/q0+NUFKktUPs2AJSpjtvw15CaHyPnAgAIHoqy4yS3ESrtcNxsxFIsNaOsFcwMnwytwAigKQIxlRlqVGu7eSByNwllw+5QmPb2ic0Z/Hlkv520N8zbtJcSVJXR/OQftZwtCVkRweAwXHOqTul80Sk4qB1w10ZAECEWOsSXynS2OrksxELSKSOrmS05jVGKhtEa3UAGG3kZzGmKkYpENm3Y/WQZ4DMXXK5/uLf9/f7fV0dOdXPuWCklpeYgWgABsdJ6imk93OfzXBDBgAQLc71Vook197G9F57AElmndOuQ8n4fFeWMX8QQDSQFMGYGo1AZNXy7+niq788Yq/3/IM3SdKIvmZrQgaiARi8NCdFSrMEOgCAiDHJnynS2KpUV6oCSeWcEpMUqS4nTgAQDbTPwpgZbMl604Gt2rbuyb6/5w5sPWEY+tHPLa8cP2Jr7OrIadXy7+naP/2Zxk2eN2Kvmy8Ub5CWsHsaSAUjqTulSRHPSFmfYx0AIFo8I1UlvFJEknYfcpo7VbSxBBLE94z2HE7GvMLq8rBXAABFJEUwZqyTKkpPfnHedHCb9u1Yowsu/XTfY3u3r9b3v/EOfeobL5yQGNmw8t7Trujo6shp9fLvqenAVnW2N+kPv/zgiCZEejW1Ok0ZR3ACpIExRl096UyKUCUCAIgiY4yqK5J/bt51yGn2FCP2JwDJsvtwMo5f1RVGzjkStwBCR1IEY8YMomT99z7/sxMeq5+zVFNnL9Wv7/hfx3x9/cv36qxl1572usoq6voSK9vWPqGHfvh5Lb30M1p00em/9tF2HXKaWMvwQyAt2rpObzdXa0tOv7rndrXkGouv19qsluYm/dGn/0ILFx87C+nrX/pj1dSO0zXXfVILFy9Va0tOG9eu0gN3397v809mT8M23fovX5Uk1dSOU1V1rT73pb8f9PeTFAEARFXSZ4pI0p7DxBtA0nR0ObV2hL2KkVFdXtwwS+IWQNhIimDMeEaqrRzemW/uksv10A8/3/f3ro6cOtsbR7yiY+6Sy1U/90J96/NT9IH/+e/HVKycrt2HnC44Y8ReDkCEdeWtCsHwv7+1Jaeffu8m/eGnv6zqmrq+x5c/ep8++5F36qbbHtCyiy/re7ytJaenH71PD9x9e99jVTV1+sa3fjykhMjyR+/TT793k77xrZ9o2sy5fWu59eavDDoxQlIEABBVFaVhr2D0JaXFDoCiJA1Zl6SqciMl59cBEGMkRTBmjDGaUDO87+2dG7J3+2rVz1mq1SM8XP1oZRV1OmvZtXroh5/X4rd9uN9ZJsOx5zAlokAaOOfU0nF6NySWP3KvHrjnDl1z3aeOSYpceuWHVFVTp+/+y1ePSYosXHy+/uBTX9Kb69dIkupnzNWlV35oSD9z07rVuukbX9DPHl57zM+86Rtf0Jvr1gwpKWKdk8fxDgAQMdmMUTZTnPeXVL3D1tmkACSDc8UNlklRXW5kvLBXAQAkRTDGaioG/tqDP/hTlVXU6bKP/MMJXyurqJUkdbU3au/21Zo6e/A7n4dj2twLtWHlvdq29skRa6O1r8nJWiePcnYg8U63dVb9jDnF12nNDfp7ll182TGJkqG69eav6o8+/RfHJER6X/essy8Y9OuUZohyAADRVVkm5drCXsXoYtg6kBy+Z7Q7QRVgtZVi8xSASCApgjGV8Y2qyqW2zhO/tv7lX2jO4v5v6DUd3CZJqp97obatfVLrXrpbq5Z/75jndHfkJEkrfv3PWvfS3SqvHKerP/4fA67lW5+fojmLL+t3jknpkeqQ3MGtg/itBqcQSIdanCbXcQEAJJkxRq2dpxe4LLv4Mv1qxe5+v9bWktOZSwafpBiMTetW65UXntI3bv7JCV+75rpPDum1ykqMOMoBAKKqstQo15acXdf9Ydg6kCxJGbIuFQetA0AUkBTBmBtXZdTWeeJJfel7PtVvlYhUHIBeN2muyirqtOiia/ut3ujqyOlbn5+iS/7H/z5ldUdXR05dR5Io/ckdKCZD6iaN7MyShgNOE2oYfggk3elWigzkZ7ffLEn6g09+aURf94G7b9e0GXNPqBIZjrKsYWcqACCyKsvDXsHoY9g6kBxJGrIuFav1ACAKSIpgzI2vNmo4eGJSpH7usr6ZIUfr6shpw8p7de2fnljRMVxlFXVa+p5PDVhJsm3dk30JmJG0+7DTBQtG9CUBRMzpDlkfSGtLTg/cdbu+cfNbQ9CPtqdhm1554amj/r71hEHtA3nl+af6Wnb1Jl6qquuG9Bq96GEOAIiyyjKjpE/5Zdg6kAxJG7JeVlLsHgIAUUBSBGMqsE4Tavo/CS666Fo9+IM/lS79zDGJkf/656u09D2fOmWCoulAscVWZ3vjCV/7xb//gfbtWK3P//OGvscuvvrLevAHf6rLPvIPxwxTX7X8e9q3Y7U++fUXhvKrDQrD1oFkc86p9TSHrB+ttSWnX91zu/Y0bFNLc5Nuuu2B/hMiu7Zr0/o1x7S62rRutT73kXfq1rt+c8qkxp5d27Rg8fn62e03H1OFsqdh26BfQ5J8T+xMBQBElrVO1SmoFGlsldq73JEEEIDYctKOA8lJcqbh+AsgPoxzLjlpZ0SetU6vb7e6+5mBt1E//+BN6mxrVFdHTp3tTVr8tutOmhDZu321Vvz6n5U7uE37dqxWWUWd5iy+THOXXK4LLv20pGJSJHdwmz71jRMTHU/e9TeS1PfzyivHnZAoGSkZX/raH2UZtg4klHNO2w7k1XCoMOKvvfL5J/Wz79+saz7yKV165YcG9T1f/9IfS5K+2c+skKNdenalps2Y22/S5VvfvF4tzU2nfA1Jqig1uugMoh0AQDQFgdOaLVb3rRiFks6I+eAlvpae4bFZAYi5W+7Pa38uGbft5k01+uRV2bCXAQCSqBTBGPM8o8m1J78wv/jqLw/pNevnLO13WPrRTvb1geaYjAaGrQPJNhJD1gey7OLLdOaSC3TNJdP1F1+/ZVAD0JddfJm+9c3rB/0z+qtCWbh4qb71zevV2pI7ZbVIRak36J8FAMBY832jyePScR2+fqfVsoV+2MsAcBqa211iEiISQ9YBRAt3LzDmBmqflRYNB5wCm5wLGwDHGq0h65JUXVOn91z5ob4kxSmfXztOUrGV1qn0zhQZ6PGNa1ed8jUqSz1ZClABABE26RQbtJJi616nQsA5GYirwDqt3ZGc1llS8V4Q90IARAVJEYy5kqxRXVXYqwjPrkNOVLEDydTVMzpD1o921tkXSFLfUPVvffN63XrzV/p9blV1rSSppbnppK85bcZcVZ2iCmTvru2nXFtlmRGHNwBAlJWVGFWWhb2K0ZcPpDd3O1luQAKx5HtGGxqSlRSZUkesACA6SIogFPXj03sq3LTLMmwdSCDrnA61jkxG5Lcvmd43D+R4VdV1kqS9u7ZJkp565F7tGSBh0ZvIOHPJBSf9eQsWn9/3egM5c8nSk35dkqrKPI5vAIDIS0u1yIYGK07LQDz15J127E9WUrN+gmG+KoDIICmCMRdYp/rx6X3rNXdI+xqtHC1mgETxjNHhEUiKtLbk1HaS1lh7GrZKkupnFOd/XPPhTww4BH3l809q2oy5p5wF8t6rfk+b1q3p92u9iZXenzcQz0hlWYIcAEC0OedSkxTZyGYsIJYC67Rxl1WQoEKRjK9UdwwBED3pvTON0BhJ0yak++J83U4nciJAshQCp+b2049cqmvqdM11nxww0fHKC0+pqqZOl175IUnSmWdf2O/MkNaWnJ5+9D599kt/d8qfeemVH1JVTZ2WP3rfCV9b/si9uua6Tw5iyLrhxgsAIPKslSamJCnS1intOsRmLCBufM9o/c5kfW4n1hp5xAoAIoSkCMac5xlNT3lSZEODpWwUSBDrnA63Bhqp0OUPPvmlfoepP3D37dq0bo1u/t6v+h679MoPHXn82MTIX3z6f+ia6z7Zlzzp9fUv/bH+8KqzT/iZ3/jWj/Xdm796zM984O7btXfXdn32/z11YqWyzOOmCwAg8jxPmjouPdfh63dYNmMBMWOt06bdCSoTUXGeCABESSbsBSCdqiuMykulzu6wVxKOPYed2jqdqsq5MACSYKRaZ/WaNnOu/uLrt/QNUG9rbVZLc5NqasfpgRW7T6ja+Iuv36Kf3X6znnr4F33P/cNPf/mEhEivqpraEx5bdvFl+tLXv6ObvvEF1dSOU0tzk6bNmKOfPvzGoNZcXebJSQxPBABEmjFG0yaEvYqxs77B6X0XcnYG4sI6px0HnLp6wl7JyJpcZxRYJ5/NoQAiwji2dSIktz+S19a96X37XfMOX8sWelwUAAngnNOKDZ0qJGtD15AsnVuqmgo/7GUAADAo/3Rnj9o6w17F2PjL67KqrSTmAOLAOqeHXw60Yl2yAos/uSKjBdNpoQUgOmifhVBY61Q/Pt0nww0NloQIkADOOTV32FQnRCSpqoxLCgBAfExLUSyydodVYNO7GQ2IE88YbWhIXmAxYyIJEQDRwh0MhMJJqU+KbNvnlC8QnABJcKhl5FpnxVFFqWFOEgAgNtK2QWvNFjZjAXFgrVPDQavG1rBXMrKqy6XKMo5BAKKFpAhC4XtGc6ak++1XCKQ3dztZdm0BsWZGeJ5IHFVTJQIAiJk0JUX2HHbac9gSdwAR53lGL6xPXpXI9InpOd4CiA/uYiA0dVVG1RVhryJc6xusqCAF4ss5p45uq658um8yVFd4sowoAwDEhOcZTZ+YrlD4+fWWqk4g4jq7ndbuSF5SZNoEjxZ+ACInXVeCiJy5Ka8W2ZjAXqFAmjhJB1PeOkuSxlf69AgGAMRKXZVUkgl7FWPn9W1WXT3clASiylqnlzdZFRIYWsyYaNgMCiBy0n1HGqEKrNPcqek+M3Z0SzsO0EILiCvPmNTPEynJGJWXcjkBAIgXY4xmTU5PLFIIpJWbGLgORJUx0ssbkxlXMGQdQBRxFwOh8T2jefW8BV/aQCk7EEfOObV1BmrrSnfFV10lx3EAQPwE1ml+ymKRlzYGDFwHIiiwTpt2OzW1hb2SkVddIVUwZB1ABKXrKhCRM6HGqLIs7FWEa+0Oq44udmwBcbS7sRD2EkI3rtJnnggAIHY8Iy2Ynq4bdY2t0ubdVIsAUeN7Ri+uT2aVyJyUt0wHEF0cnRC6OVPSFYwcL7DSSxstLbSAmAmsdKA5mcHLUIyr8iiHBwDEjjFGU8d7qigNeyVj6/n1VIsAUeKcU67N6c3dybwfsGCaIRELIJJIiiBUQeA0dypvw5WbAonYBIgN65z2NRWU9uv7sqxRaZZjOAAgvtI243DTbqeWdidHlScQCU7SC+sDJfUTuXCmRyIWQCRxJwOh8n2j+fWcIHPt0qZdjh0UQEx4xmhPE62zxlV53FQBAMRWYJ3OmJaukNg56YUNyb0BC8SNs9KqzcmcUThlnFEV80QARFS6rgARSZPqvNTPFZGKu0PYQQFEn3VOTW2BOnu4nVBX6XNTBQAQW75ntGB6+kLiV960Yk8DEL7AOr22zaqjO+yVjI4F0wxtwgFEVvquABE5zjmdOYO34pY9Tk1tlLIDUecZw4D1I8ZV+cwTAQDEWl2V0biqsFcxttq7pDWbGbgOhM33jFasS2aViCQtnOHRJhxAZHEnGqFzTlo0i7di0nuJAkngnFN33upwKwPWK0uNsj5RDgAg3pxzmlefvljkyVe5lgHCFFin17cF2tuYzDsA2Yw0e4phAxWAyErf1R8ix/OMzphmlPHDXkn4Vm22ssndKAIkwh6qRCQdaZ1FZRsAIOask+ZPS99Nu+Z26YX1ltY2QEiMpMdXJTc5OXeKoT04gEgjKYJIyGaM5k3lhNnZLb22lVJ2IMr25kiKSMXWWQAAxJ3vGZ0xzUtlh5enXwtUSO49WSCyrHV6eZPV4dawVzJ6zpjucV8DQKSRFEEkBNbpzJm8HSXpxQ2WHRVABFnndLAlUJ6ciHxPGlflyVAODwBIgIpSoynj0ndO6+iWnnk9kKXyExhT1knLE97C7swZHvc1AEQad6ERCb5ntGQ2b0dJ2n3YacteqkWAqPGM0c5D+bCXEQkTqhmwDgBIDuuc5tWn87y2Yp1VZ7doiQmMEWudnltr1doZ9kpGT12lNKEmncdUAPHBXWhERlW5Uf14TpyS9MjKgF0VQIRY57Q/V1B7FzcMJGlybYabJwCA5HDSgmnpDI17CtKTa5K9Yx2ICuecegrSs28k+zN3xnSPWAFA5KXzyg+RZK3Tolm8JSVpz2GnN7YHVIsAEWEkbT9AlYhE6ywAQPJ4ntGcqUZ+SkORlZusmttFGy1gDCx/NVBXT9irGF0LpnvicAIg6lJ62YcoMkZaPJubbL0eWxWIe45A+Jxz2tNUUFeeK3tJmkjrLABAAmUzRgump/P8Fljp0VcCzu/AKLLOqa1LemGDDXspo8oz0hnTjDw6XwCIOJIiiAxjjKaO8zSpNuyVRMPhFumVTVaWahEgVNZJOw5SJdJrEq2zAAAJFFin8+enNzx+fZvV/iZiD2C0eMbo8VWBCsnunKUZk4xKsyREAERfeq/6EEnWOp0/3w97GZHx5JpAxCVAeJxz2nW4oHwh7JVEQ4bWWQCAhPI9o0UzPZVmw15JOJykh1cG7O4GRoG1TodbnFZvTnaViCSdPcejDTiAWCApgkjxPKOlZ3jiUryotVN6bi07toAwOOcUWKnhEFUivSbU+ByfAQCJ5XnSktnpDZHf3O20ocFyQxMYYZ5n9MALhcRvePQ9ael8Tz7JVQAxkN4rPkRWTYXR7CmcRHs9+0bALnUgJDsO5hUkf0PXoE2uyYS9BAAARo1z0tIz0h0i/3JFQYUCQ9eBkWKt08pNgTbvSf5nasF0o/JS7uUAiId0X/EhktLez/d4XT3SU68F9PAHxpBzTj0Fp92NZCR7ZXxaZwEAks3zjOZMMaqtCHsl4WntlB54gaHrwEiwtjhc/aGXEz5I5IgLF/hUmgGIDe48I3J8z+icuZ4yjBbp88J6q/YudmwBY8UYo20H8uIj95aJ1RyUAQDJ5ySdMy/dYfKarZY2WsAI8Dyje39TUHcKuvFWlEpnzjC0zgIQG+m+2kNklWaNzpzBybRXIZAeX8WOLWAsOOfU0W21P5eOHV2DNbmW1lkAgOQzki5IeQstiTZawOlKU9ssSTp3niduVwCIE672EEmBdVp6BruSj7Zqs9WuQ+zYAkabMUZv7u0JexmRUlZiNK7Kp3UWACDxjDGaXOdpyrh0n/NoowUMX9raZknSsgXcXgQQLxy1EEm+Z7RwulFFadgriQ7rpF88WyjW9AMYFc457W7MK9fOdPWjTRuXYacoACA1Aut0fspbaEm00QKGK01tsyRp6jijqeOZPQggXrjSQ3QZadlC3qJHO9gsPbaaoevAaHDOqbvgtHV/SqKXQfKMVD8uw05RAEBq+J7R0jNoBSPRRgsYqrS1zZKkpWd4JE8BxA53nBFZRtI7zvLFnK5jrVhrteew46IDGGHGGG3c1SNLkcgxJtX6yvgciAEA6VJVbjR3Cuc/2mgBg5fGtlmekZbO9xiwDiB2SIogsowxqqk0OnMmJ9ejWSfdQxstYET1tc3qICNyvOnjM1SnAQBSJ7BO580nXJZoowUMVtraZknSgulGFWXcswEQP1zlIdIC63TJIgauH482WsDIoW3WwKrLPFWXM2AdAJA+vmd0zlxPGUIRSdL9Kwrq7C7uhAdwIuecnl+XrrZZknThAp+EKYBYIimCSPM9o7n1nibVhr2S6KGNFjAyaJs1sGnjGbAOAEivkozRktmEzJLU1in95ImCnBMbs4DjBNZp+36XqrZZklReKp0509A6C0AscYWHyAus09vPYovW8WijBZw+2mYNLONLk2t9eogDAFLLWqd3n0PI3GvXIaf7VgRUkAJHCaxTa4f006cKStt+xXPnesyABRBbXOEh8nzP6MIFnkqzYa8kemijBQwfbbNObmpdRtzzAACkmecZTRnn6YxpnBB7rdli9Zs3iD8ASbLOKbDSjx4vtpdLm7ed6bFHE0BskRRBLGR8aSmDDvtFGy1geGibdXLTx2fCXgIAAKGz1uk951C1frRHXinOTWC+CNLOM0Z3PV3QgVz6PgsLpheTxlSVA4gr7jIjFpykS5b47Fruh3XS3c8WFFjR+x8YJOecdh2mbdZAxlV5KivxaI8BAEg978iMw2kTOCf2ck668+mCmtrExiyk2mOrCtrQkM7PwHvP80mMAog1kiKIBc8Yja9m0OFADjVLdz1dYJcGMAjWOTV3WG3dR9usgcyckCXJCgDAEYF1etfZxCFH6+qRfvx4XoWAjVlIH2udXt8W6OnX0rnBavZko1mTPXkMFAEQY1zZITasdbrsfE+cdvu3ocHpsVWFsJcBRJp1Tj15p7UN3fS/HUBNuadxVQxYBwCgl+8ZnT3H0/jqsFcSLYdapJ8vLxCfIVUC63Qg53Tvb4KwlxKaS8/zqRIDEHskRRAbnmc0uc7TWbO47B7I069Zvb4toIwV6IdzTs5Jr+/sViG9McwpzZ5MlQgAAMezTrpkMbNFjvfmbqeHV3JhhXSw1qm7R/rx4wXlU/q2rx9vtGC6J58qEQAxR1IEsVKsFiEYOZl7fxPoQI7B60B/1u/qUUc3n42B1JR7Gk+VCAAAJ/A9o2ULPVWUhr2S6HlurdWaLQGbKpBo1jk5ST95sqDmjrBXE55Lz6VKBEAykBRBrHieUf14Twunc8NuIPlA+vETBXX3iIoR4CjbD+R1uDWlW7oGiSoRAAAG5hnpHYvYoNWf+54L9OZux3UEEqn3ff3z5QXtPJDe9/jEWmnxbEOVCIBEICmC2KFa5NSa24s7WJyKLYOANHPO6UBzQTsPMXPnZKgSAQDg5DzP6JLFnrKZsFcSPYGVfvZUQdv2OTZmIVGcczKS7no60Pqd6X5vv/scX3y8ASQFSRHEjucZzZjkaV49N+5OZucBp1+uCGS4wYkUs86pvdtp4+6esJcSeVSJAABwaqVZ6cIFhNH9KQTSTx4vqOEgiREkQ+8Gw1/8JtAb223IqwlXXaV0/jxmiQBIDq7mEEsB1SKDsmqz1Yp1AdUiSCXnnIJAemNHNzuaTqGaKhEAAAbt3Wf74r5g//KB9MPHCtp9mMQI4s8Yo18+H2jNlnQnRCTpt872xScaQJKQFEEs+Z7RnCme5lMtckoPvxxoK2XsSBl3ZBDiGzu71V3gvX8qc6gSAQBgUIwxqqk0OnsOofRAegrSDx4taE8jMQjiqXdT4QMvFLRyEwmRyjLpooVUiQBIFq7kEFvWOl39Nl9sbD4564r9fQ82OwUEJUiB3iBmw64etXQSxJwKVSIAAAyNtU6XnucRh5xEd16645GCdh0iMYJ46Y0l7n+uoBc3EEtI0iWLqY4DkDwkRRBbnmc0ZZyn8+fxNj6Vrh7p+w8X1NQqEiNIPGOMNu7p0cGWIOylxAJVIgAADI3nGU2u83T+fOKQk+nOS3c8WtD2/SRGEA+918S/eDbQyjdJiEhSWYl08SJPHlkRAAnDVRxizTqnK5f5yjJe5JQ6uqXvPZxXSzuJESTbpj092p8jITIYNVSJAAAwLNY5vf9C4pBTyRekHz1e0Ja9jk0YiLTe9+edTwdas5WESK9LFvvKZMJeBQCMPJIiiDXPGFWVSZcs4a08GG2d0vceyqutk8QIkmnz3h7tbSqEvYzYWFCf7WsRAAAABs8zRpXEIYNSCKSfPFHQhp2O6w5EUmCdnC22nX5jOwmRXjUV0rvO9thABSCRuIJD7Blj9J5zfVWWhb2SeGjuKCZGOrpIjCBZtu7v0e5GEiKDNXWcr6pyX4YgBwCAYSEOGbzASj9bXtAzrxdvOFM1gqgIrFNnt/Tdhwpav5P35dGuvNCXx11DAAnF4Q2JkPGky8+ndn2wmtqk7z5IxQiSY8u+HjUcIiEyWBlPmjelhN2aAACcpownXUYcMijOSY+tCnTX0wVZK+aMIHTWOe1rdPr3/85r9yHej0ebPtHo/Pm+fGaJAEgokiJIBM8zWnamp0m1Ya8kPprapO/+mhkjiK/eG/pv7u3RrsMkRIZizuSsMp6oEgEA4DR5ntFFZ3qaSBwyaK9ts/rugwW1dxOHIFyvbbW67aGCWjvDXkn0/PbbfT6fABKNpAgSwznpAxcxAWwomjukWx/Mq6mVgATx0psQ2binW3tomTUklaVG08ZnSIgAADBCnJOuJg4Zkj2Hi7vz9x5mADvGlnXF2TYPvVzQPc8GKgRhryh6zp7jaeYkjyoRAIlGUgSJ4XtGC2d4OmsmJ+6haOuUbnsor0PNjhJ2xEJvQmTD7h7tayKKGaoF9SXikw4AwMjpjUPOnEEcMhRtndL3Hi5ozWYGW2NsBNYpX5B+9HhBz63lfdefjC9dfZFPshJA4pEUQaJY5/Q7F2dUwkatIWnvkr73UEHb9ztmDCDSrHOyTlrb0KMDzSREhmpSja/aSl8eVSIAAIwoa51++x0ZZRgvMiSFQLr3uUAPvlSQc2zSwuix1inXJv3nA3m9uZv32UDedban6goRLwBIPJIiSBTPGFWVS+89j2hkqDp7pB88WtAL64s7ZkiOIGqcc+rJO63e2qXDrSREhsrzpDPqGa4OAMBo8Dyjukrpt5YQYg/HinVWP3ysoHyBtr4Yec45bd3r9J+/yutQS9iria7x1dKl5/q02QWQClyxIXE8Y/RbSzxNqeNEPlTWSb9+KdB9zxVkndiphchwzqm5w+qVrV1q7+Z9ORyzJ2aV9RmuDgDAaDHG6NJzfdVWhL2SeNq8x+k/flVs68smDowEa4vvpWffsPrh4wV19YS9omi75h0ZiVABQEqQFEEiOUkfeqcv7v0NzytvWt3+cEFdeXZqIVy9AfGexoJe297NIMRhKi8xmjGR4eoAAIw2z5Ouuoiq9eE63CL9xwMFPfWqlbWOWATDZp1Trl267aGCHn0lEHm2k1s8y2jBdIarA0gP49iCgQT71QsFvbCBAWrDVVsp/ckVGU2uNfK4OMIY6z09vbm3R3sZqH5azp1dqtpKj97AAACMkdsfzmvrPkLt01E/3ujD7/I1uc6wsQODZq2TMdJza62eWB0oTxhxSiUZ6f+9NqvKcmaJAEgPkiJILOecCoH0r/fl1dwe9mriK5uRfu+dvs6ew443jB3rnAIrrd3ZreYOEpuno35cRgunlYS9DAAAUsNap5YO6Tv359VTCHs18eZ70nvO9XXpuZ6cxC52nJR1xWHq9zxb0M4D3OoarCsv9PXOs9lABSBdSIog0QLrtGWP048eJxo5XZee6+mKCzKyznGxhFHlnFNHt9PrO7vVnecUdTrKSoyWzS+TZ5glAgDAWLLWadVmq/tXsE19JFA1gpOhOmT4JtcZfeF3MnSGAJA6JEWQCvc9V9Arb7Lb/HQtmmX0kXdn5Hns0sLoOdhc0IY9PbJ8ZE/b0rmlqipn1xcAAGH5yRN5bWgg5B4JVI2gP1SHDJ/vSX96TUYTaw2fJwCpQ1IEidfbRuvffpnX4dawVxN/k2ql696dUf14dmlh5FjnJCdtPZDX7sNUdo2EmRMzmjs5y+cUAICQWOfU1S19+/682rvCXk1yUDUCieqQkXDVMl+XLGEDFYB0IimCVAis075Gp1t/XZDlHX/aPCO982xPly8tzhlhVwlOV3NHoI27e9TZwwd0JFSWGl0wv4wABwCAkAXWadMup/96kk0fI8n3pHcu8fTuc31lfdH6J0WsdfI8o92HrH71YqCGg8QPwzG/3ugT78+GvQwACA1JEaSGc05PvWr15Bq2kIyUyXXFXVpUjWA4qA4ZHcZIF84rU3mpISkCAEBE3PubglZtpjfoSCsvld5zjq+LF3mSYbNWkvXOtjzc4vTIyoLW7eRW1nBVlEpf/GBWFaUkFAGkF0kRpIpzTt99sMBukhFE1QiGi+qQ0TF3SlYzJ2RIVAIAEBHOOeUD6Zb782pqC3s1yVRbKV12vq8LzvBkHTFJkvTesmrrkh5fFWj1Zkv3h9P0R5dltHAGc0QApBtJEaSKtU4tHdJ37s+rh43pI4qqEQwG1SGjq6bC0/lzSvkMAgAQMYF12n3I6baHCiICHz2TaqUrL8xo0SxPgXXc9I05a516CtLyVwO9sMGqQNOH07ZsoacPXpIJexkAEDqSIkgda51Wb7G67zmuqEYaVSM4FapDRo/vScvml6k0S2ISAIAocs7p0VcCPfsGbbRG28xJRlct8zV7itc3gwLxYa2TdcUh6s++EairJ+wVJcPEWukLv5OV74l4AUDqkRRBav3sqbzW7uDtPxqOrhpxEnMNUo7qkLGxcFqJptb5BDgAAERYYJ3+81cF7WskDhkLC6YXkyNTxlE5Egf2SF+slzdZLX81UGtnyAtKEN+T/tdvZzSpjrZZACCRFEFKWedUKEj/8UBeh1rCXk0yeUa6cKGnK5b6qihlJ0oa9Q5D3J8raPuBvLrynG5Gy5RaX2fNKA17GQAA4BQC63S4xek/HijQCmiMGElnzjR6xyJfZ0wjORI1vZU8XT1OKzdZvbQxUGNr2KtKnisv9PWusz3icgA4gqQIUiuwTo2tTv/5QIH5IqMom5EuXuTpPef6yvqidD0FepMhjW2Btu7vUXsXp5nRVFVmtHRumYwh+QgAQBxY57RirdXDK8mKjLUJ1dJFZ/q6aKGnkqzkHPFJWHqTU3sOWz2/3ur1bcwMGS3zphp94v0ZYgUAOApJEaSatU7rdjr9fDlZkdFWXiK9+xxflyz2JMO8kSRyzskYo5bOQFv35dXcQb/s0Zb1pQvnlymbMbSpAwAgRpxz+sGjBW3ZSzgehqwvnTPX08WLPNVPoHpkrFjnZCQFVnp1q9VLG6x2H+YzMJrKS6UvfjCrylISgABwNJIigKSHXi7oubXcwB0LNRXSZef7umCBJ+dIjiRBbzKko9tq6/68DreyxWusnDenVDUVHgkRAABixlqnniPtfGkVFK7pE4zefpan8+Z5MsX9W+yoH2G9SaemVqfn1wf/f3t3FhzXdd95/HfOvb2gARAbARIkQRIQSXHRRkqyLHkVtVimllj2WGPJjkexlMgjTSVTiZ0HZR7mJa7KlB9HciajmtjO1LhGGdOZcUw7kqXItjZrozaSEjdwBUhwA0kQC9H3nHm4aO6UAOICvX0/VVCDjavLA1Y3cP/3d875a/1WpyGap0+LB24OtbTDEIgAwDkIRQDFN3X//l/y2r6Pt8N0mdkg3bYq1IoFzMwqV4VfHyfzXt19o9rfTxgynbpmpTSvhWXwAACUq8h59Q9IP/jnUQ1zg7joajLSqkVWNywN1Fxv5Jxne9JJKNR4znlt3uv16qZI23q8qLinzw1Lre7+ZFjsYQBASSIUARTP1BoZlf7r/x3V0cFij6a6zJ1pdMd1gTpnE46Ui8KvjchJOw+Mau/hvPhNMr3aGgIto7E6AABlzzmv7b1eP/51Xo7rqZLR2iAtm2+1bL7VvJlxfeJY5f6xCvXcyKjXpl1OH+z22rLXaWS02COrPovnGn3zViZQAcDFEIoAYyLnte+w19+tyytiJ61p19FqdMPlVld22XhGlpiVVWoKDdRPDDvtPZxX31HeK8VQmzVaRWN1AAAqhvder2xyWvcaq25LUW1Wunye1dL5VovnGKVCw2SuMd77U83qjwx4bdzp9MFup537PSFfEc1qNHrkzlBhKLbZBYCLIBQBzuC819vbnNa+SEFSLLmMtGqx1Y3LAjXUUnAUW+FXhJd04GikniN5HaOBetGEY43VM6EhEAEAoML800t5vbGF66xSFgZS12yjpfOtls+3qquJt4eSqqeJdRR5WRt/vufg6SDkwNHijguxuhrp0btTqs2ysgkAPgqhCHABz78d6fm3CUaKyRhp8RyjTy4LtHiuOTUDCdOjsCpkZNSp53BevUfyGuUtUXRXLciosdYSiAAAUGEKM+7/x7/ktWM/JXo5MJLaW4wWzTGa22LV0Wo0o3Zsq60KCUoKAYgxRlHktb/fa/cBrz0HvDbvdToxXOwR4kypQHp4TajZTYZABAA+BqEIcBFrX8zrra3M1CoFTXXS9ZcHun6JVU0mno1V7gVGqfLeyxijwwOReg7ndeg4SUipoLE6AACVrdDn8Mmfj+rIQLFHg0uRy0hzWozmtJRfUHJWAOK89h+JA5CeQ157D3n1HWFLrFJmJH3t5lDLOkzJvsYAoJQQigAXUJip9eNf57W1h7dIqQgDacUCq08utepos2ftYYvJG4289h2JV4UMneR1X0ram0ItmZMu9jAAAMAUi5zX4eNef/vPeZpTV4hCUDK3xWhOi1V7i1FdjZQOz65hnItDB2uSrW+893Jjc/0KoceZXxsakY4MeO05GAcgPYe8+vo9vQPLzO3XBvrMFawoB4DxIhQBLsJ5r3wk/d26vPYd5m1Saupq4oaHy+ZbLZpjFAb0H5ms17YMEYaUoJn1gZZ3pClwAACoEs55be3x+ofn8qJar1zpUKrPSfU1RvU5o/oaqT5nNKNGmlFr1FBrVJeV0qmJXwO6sbDj+KBX/4n48fhQ4dHr2KB0fMjrxJBY/VEBrl1sde+nwmIPAwDKCqEI8BGc8xockX7w81EdHSz2aHAxqUDqajdaNj8OSWqzcUBijbiRPE7ee23bN6q9h/PFHgrO0JCzumphRka8lgEAqCbee720welXb7CVabULg/gjXkFy+jEwkpcUOcm5ONwoPI7mCTuqRVe70YO3hTLUvgAwIYQiwMeInNfhY17/bV1ewyeLPRp8HCNp7kyjpR1WKxYYtTZaubFttlhFcnHeex0ecHp/10ixh4IxuYzRys6sAkuBAwBAtfrZS3m9uYV9jACcr7VB+vZdKaUCtpQGgIkiFAHGwTmvnX1eP3o2rzyTtcpKU520ZF7c5LCj1aq5Pr7BTFByvsh5vfTBENs0lIBMymhVZ1ZhKFkCEQAAqpL3cY+JHz+b17ZeLtAAnJbLSI/enVJ9jpoWAC4FoQgwTs55bev1+p/P5Wk6V8bSodTebOJmhzPLLygpFMeFMQ6f9MqkkltJ8E73sPoHeYEXUyqQVnZllUkZAhEAAKpcofn2j5/Na/s+SncA8XZqD90Rak6LKenaFQBKGaEIMAHOe23e4/WTfyUYqSRnBiVzWow6Wo0a6+Lm7WdyLg5NjJma5cmFwEM+3if43KBjcNir97DXnoNeew859Rzy6h+QvvWFUAtnT/4GuvNeew7m1d03Oqnz4NKFVrqmM6uaDIEIAACIFYKRHz2bVzfBCFDVAis9cHOoxfOoFwBgMghFgAly3mvTLq///UKe5nUVLpuW6muk+pzRjBqjupw0I2dUXyM11BrNyBnV1ei88GQivPcaHJGOD3kdOyEdG/Q6PigdG/I6Pvb58SGvgaGLN0v8zBVWt60KJh3UeO91YsTrzW3DkzoPLo210tULMqqrsRQ4AADgLM55RS4ORnbspwgBqlEYxIHIorkEIgAwWYQiwCXw3uu9HU7/+NuI/gtQJiXVZuNZO9YaWRPf4LYmfs57KfKSc3Gw4Vxc2I7kpRMfEXaMV3uz0WP3pJL5ZiS9/MGgRumdM62Mka6cn1FjraWpOgAAuKBCMPLDZ/La2UcRAlSTMJC+sTpU1xwCEQBIQljsAQDlyBijKxdaRZG09sVIlCTVbWQ0/ohN/6th32GvwRGvXCaZi+PG2kAHjpGKTBdrpBUdBCIAAOCjxauCvf7d7aF++ExeuwhGgKqQCqRv3BqqcxaBCAAkxRZ7AEC5Msbomsus/uCmQFyWoJi8pC17nKIE9nNz3qu5Lpj8oDAugZWuWpBRUx2BCAAA+HjWGoVWevD2UB2tXDsAlS4VSt+8bSwQoak6ACSGUASYBGOMrl1sdc+NgbifiWLa0uMVJHCRbI1Rcz2hyHQIA+nqhRnNyBGIAACA8SsEI390e6h5BCNAxUqH0oO3hVrQRiACAEkjFAEmyRij65ZY/dvPBQp4R6FItva4xM6VDk1iW3HhwtKhdM3CrOqyBCIAAGDirDUKgzgYmTuTawmg0qTD0yvCCEQAIHncwgUSYIzR8gVW37w1VJpOPSiCgSGprz+ZYMSzhdaUyqSMrunMqiZjCEQAAMAls9YoFUjf+kKoOS1cUwCVIpOS/ugLoebNJBABgKlCKAIkxBqjztlG37ojVE2m2KNBNfpwj0+kr4gkNRGKTImatNHKzowyKZokAgCAySsEIw8RjAAVIZuOg865LQQiADCVCEWABFlrNKfZ6JE1Kc3IFXs0qDZb97pE+ooYY9SYs/TJSVhtxmhlZ1apkEAEAAAkx1qjVBjfSKXHCFC+atJxwNneTCACAFONUARImLVGTfXSt+9MqWVGsUeDarKzzysfJbNSxNo4GEEy6musrunMKghEIAIAABJnrVE6lB6+I9Ty+VxrAOWmJiM9dEeoWU0EIgAwHYz3Ppk7aADOEjmvkVHph8/k1XOItxmmx4O3h+qaPfkLaee99h7Ka/v+0YRGVr0aa62umJ+RNaKHCAAAmFLOexlJ616P9MrGZPrNFcum19eqe8Ovz3pu9X3fUzbXOKljz9W7Y71e/sV/0eqv/rWa2romM2TgkjTXSw/ellJDnRJZ+Q8A+HiEIsAUcs4rctLTv81r0y7eaph6n1ph9YXrgkRWI5wYdnpj23ACo6pes5sCLW5Py4hABAAATK+XN0b65euRyrHif/7px9W54hZ1rrjl1HNH+rZr7ZMP6Ot/+auzwo6JHHshm15fq7VP3v+xY3r0bzYRmiBxC9qM/vDWUKmQQAQAplNY7AEAlcxaI2O8vr46pWffyus375b3bC2Uvq17vb54fTIX07VZq3QoncwncrqqYiRdNjuluS0pee8JRAAAwLS7cZlVU53R07/JazQq9mjGr3fHekk6K+SQpKa2Lq158Af6xd//e33lsZ9M+NiL/n3db2jl5x66aOAxNHD41DmBJF3TZXXvpwMZiS2zAGCaEYoAU6xwM/S2VaFmNUVa+2KkfBkVJSgv+/u9Boa96rLJXFQ31gbqO8oLdiLCQFrRkVHDWE8WAhEAAFAMxhhdPk96+Iuh/uG5vAaGij2i8dmx8Tm1d153wa+1L1ypfTvXX9KxH2XNg09e9GvPP/24Vt/3vXGdBxgPI2n1ykA3Xx0wgQoAioQuusA0umKB1Z+sCVVfU+yRoJJt3uMUucnvk+C8V3NdkMCIqkcuY3RtV1YNOUtxAwAAis5ao9nNRo/dnVJ7c/lcm6x/4b9f8PkjfdvV1Np5ycdeyMVCFUl664WntPLzD3/sOYDxCgPpvs/FgYjEBCoAKBZCEWAaWWs0q8nosXtSmtvCxQ+mxta9PpH9aK0xhCIT0FIXaFVXVumUobgBAAAlI7BGtVnpkTtDXbGw9G8BLL3uy+re+Lx++sT9Gh7sP+trr6z7vm5c851LOvZill3/5Qs+f6RvuyS2zUJyGnLSn6wJtWJB6b8PAaDS8ZMYmGaBNcplpD9eE+qqTt6CSN623uR616RCo9qEtuKqZB0zQ62Yn5Y1SqTJPQAAQJKsNQqs9LXPh7plZdzDoFQ1tXVp9Vf/Wh+8sVZPfPdydW94TlK8aqNzxa1n9Q+ZyLET9cq672sVq0SQkIWz4smRs5oM/UMAoAQY7/3k91gBMGGFvUNf2hDpmTcjRfRgR4L+wz2hZjVNfsWC917d+0e1+xDd1i/EGunyOWm1NdKiCwAAlAfvvTbt8vo/v8vrZAlf4m16fa3WPnm/JKmxtVMPfGfdRVdtTOTY8XjrhafUvvBatS9cecnnAApuWGp15yfiFfgEIgBQGpimDhRJ4Wb1TcutHrkzVHN9kQeEivLhHq8E2opIkprYQuuC0qHRys6MWhv49wEAAOXDGKOlHUbfvitUa0OxR3Nx2VyDbvziX6hz+Wr1H+jW//r+GvXuuHDj9IkcOx4fvP5TAhFMWhhI934q0N2fDGUtK0QAoJSwUgQoAZHzykfSz16K9P4Oloxg8jpnGz10RyqRcznv9dKmocRClkrQUh9o6dy0rGW7LAAAUJ4i5+W9tO61SK99WFo1yPNPP672zutO9ft464Wn9MsfPSZJeuA7687aFmsix47HWy88pf6+7Vp93/eS+FZQpRpy0gOrQ7W3GOoFAChBrBQBSkBgjVJhvMfvPTcGCpl4jkna1ec1mk8mxbDGqLGWXxdSvF3W4vaUrpifUUAgAgAAylgw1mfknhtD/eEtoWqzxR5R7K0XnpJ0dgP0VZ9/WI/+zSY1tnZq7ZMPnGqqPpFjx2v9C09NqhcJcHWX1Z/em9LsZgIRAChV3OUCSkThYum6JVaP3h1qZgkvZUfpi5zUvc/LJbC8w3nPFlqS6rJW1y3Kqr0p7h8y2X4tAAAAxVa4nlk01+jPvpTSkrnFv755Zd33L7hKo6mtSw/951clSd0bnp/wseNxpG+79u1cr8bWzksZOqpcLiPd//lQX/1sqHQYB48AgNJEKAKUGGuMWmYYPXZ3Sisv4y2KS7dlr5MSuA63xqi5ykORjpmhVnVllElNvnk9AABAqQmsUTYtffO2lO6+IVCqSJd+w4P9yuYaL/r1bK5RN935XfUf2D6hY8ere2McoEymSTuq05J5Rn92b0rL5se1AjUDAJQ27rgCJSiwRmEgfeUzoR64uXSWsqO8bOlxiS3XzmWs0mH1XdhnUkbXLMyosy0lY1j+DgAAKlehCfT1S60euyel9ubpv+7J5hrHtd1VY2vXhI4dr3073hr3sYAkpUPpD24M9M1bU6pJi2bqAFAmCEWAElWYWXJ5h9F/vDelFQu4uMLEHDwqHR9Mpq+I915NddX1K6N1RqDrLsuqPmeZ6QUAAKqGNUZN9dK37wr16RU2iYXHE9LU2qnuDc9d9OvdG55T54rVEz52PPoPdH/k6hPgTAvajP70SylduziukwhEAKB8VNcdLqAMFZay339zSvd9LlAuU+wRoZx8uMcpSqCviJeqZgutwEqXz01reQfN1AEAQHWKm7AbfeG6QN+6I1RDbvr+7i8/9hM9/49/dV7YMTzYr3U/fFQ3rvnOqeBiIsdK0k+fuF9P/OXSi/7dRw50J/Z9oHIFVrr92kAPfzHUjBxhCACUI+O9T2YaMYAp55zXyKj0/16N9F63K/ZwUAauWGj1tc+HiZwrH3m99MFQIucqVc11VovnpJUJ6R0CAAAgSZHzyueln70c6f0d01eDPP/04+dtj7X6vu9dcCXHeI/96RP3q/9A96km7Of66RP3a2SwXw9895eTGDkq2awmo/s+G6itkXoBAMoZoQhQZpz3ssbow91O//RKXscHiz0ilLKajPT411KJXbC/uW1YA8OVF8hlUkaLZqc0c0Yo7z0FDgAAwBkKNcg72yP98vVIA5U9TwY4jzHSp1dY3boqXj0fsDoEAMoaoQhQpiLnFUXSr9dHenWTUwI7JKFCPXp3qPbmyc9k8t5rR9+odh3MJzSy4jNGmtccakFbSsawVRYAAMBHiZxX5KTn3470ykanqPLmygDnaWs0+tJNgTpaWR0CAJWCUAQoY4W376Fj0s9fzWtbL29nnO+WlYE+e6Wd9Gwm772ODTq9vWMkoZEVV0POasmctGrSFDcAAAAT4b1X/4D089/ntXkPNQgqUy4T11LXX27lPatDAKCSEIoAFcA5L2uNNu50Wvd6Xv0DxR4RSsmCNqM/XpNK5Fzex31FynlWYCqQumanNbuRrbIAAAAuVaEG2bzH6Rev5XXoWLFHBCQjsNInl1mtviZQKqCROgBUIkIRoIJEzst76bfvOf3uvUijUbFHhFJgjfSfvp5SOkzmYv79nSM6NFCeL672plBds1IKrAhDAAAAEhCN7eP78ganF96NNDJa5AEBk7BsvtGaT4RqrI3/TM0AAJWJUASoQM57DQxKv3gtrw07eYtD+sYtoZbMNZOe5eS8V+/hvLbuK69qtz5rtXhOSvU1AatDAAAApoBzXkMnpV+9HuntbU5UISgns5uN7vpEoIWz7alVUACAykUoAlQo572sMdrV5/TMm5F27OetXs1uWGp11w1BImHA0Emn17YMJzCqqZfLGC1sS6l1RnjqPQEAAICpUbje2nPQ6eevRNp7iBoEpa2uRrp1ZaBrF1s5+oYAQNUgFAEqXOS8Amu0rcfpmbci7T3IW74aNddLf/6VdGLne3XzkEZGS/e1lE0bLWxNqa0hkJcIQwAAAKZRoQZ5c0ukZ96MdKI85tOgioSB9KnlVp+7OlBo6RsCANWGUASoEoXC5IPdTs++FWn/Ed761ea7X02poXbyF/vee23uPal9R0qvr0gmZbSgNaXZjYQhAAAAxeacV95Jr2x0enkj4QhKwxULrb54faAZOXqGAEC1IhQBqkwhHHmvO9Jz6yMdPFbsEWG63HNjvCx8skvCvfc6eCzSxj0nExrZ5KVCaf7MlOY0h5IIQwAAAEqJc17OS29sdnpxQ6T+gWKPCNXGGGn5fKPPXhVobotla10AqHKEIkCVipyXMdLb25x+916kA0eLPSJMteXzjR5YnUrkXPnI66UPhhI512SEgdQxM6V5zaGMYaYXAABAKSvUIO9ud/rte059/dyOwNQKA2nVIqvPXBmoqc7QRB0AIIlQBKh6hZUjH+52+t37NGSvZNm09PjXUokVAW9tH9bxIZfIuSYqFUhzmlPqmBnKEoYAAACUlUINsmmX02/ejbSHvodIWC4j3bDU6qblgbJpsbUuAOAshCIAJJ0uTHoPOf32facNO5wcPx0qziN3hpo300w6RPDea+eBUe08kE9oZONTmzGa25LSrMZARoQhAAAA5axQg3Tvc3rhnUjbeilAMDnN9dJNywNdt8TKGhqoAwAujFAEwFkKy4mPnvB6cUOkNzc7nZze+96YQjdfbXXz1cGkiwPvvY4NOb3dPZLQyD5aS32gjpZQDbUB+/8CAABUmDMnaP3ru5E27fTiRgUmYm6L0WeutFq+wMp7TbqPIgCgshGKALigwo+Gk3nptQ+d3tgc6RBN2cteR6vRI3cm01fE+7ivSDRFO2iFVprdFGpeS6hMysp7z8oQAACAClaYoHXomNdv3o30brdTPir2qFCqjKTF84w+e2WghbPsqXANAICPQygC4GMVipOdfU6vfxhvrTVKcVKWrJH+6oGUMqlkioX3d43o0PFkXwy5tNHcllCzGuN+IRLbZAEAAFSTwsrgkVGv9Vud3tzi1HuYWxeIpUPpyk6rT19h1dpgaZ4OAJgwQhEA41a42Dw56rV+m9MbmylOytH9N4da1mEmXTg477XvSF5bekcnPSZjpOa6QHObQzXVsUUWAAAAYoXZ//sOO72+2emd7U7DJ4s9Kkw3I6lzttGqRVYrFlqFAc3TAQCXjlAEwCU5VZwciVePUJyUj+uXWN1zY5DI6ovhk06/3zJ8yf9/Q86qrSFUW0OgMDCEIQAAALgg572MJOek93c6rd/qtL3Xy3FHo6I110srFwW6drHVjJxhiywAQCIIRQBMSuFHiPPSth6v97qdNu0mICllTXXSX/ybdGLn+/3mIQ2Pjv9XSV3WqK0h3h4rHRKEAAAAYGIKN8ZPDHu9sz2eoLX3ILc2KkVdjbRigdU1XVYdbWyPBQBIHqEIgMQ452VMHJBs7z0dkAyNFHtkONeffyWl5vrJFxbee23tHVXPkfxHHleTNmprCDSrMVRN2hKEAAAAIBGFgOTI8XiL33e2Rzp0rNijwkTlMnEQclWX1YJZRkZsjwUAmDqEIgCmRCEg8V7avs/r/W6njbucBglISsJdNwS6/nI76aXn3nsdOh5pw+7zlwalQ6PWGYFmNQaqrwlOrSqiaToAAACS5r2X95K1RvuPOH24x2trj9PO/V6RK/bocCG1WenyeXEQ0jXbnKofWRUCAJhqhCIAplwhIJGknkNeW/bGBcruAxQoxbK0w+gbt6QSOVfkvF7aNCSvuEdIc12glvpAtVlLEAIAAIBp533caySwRvnIq7vXa3OP09a9TgeOFnt01SuTkhbOMupqt1o816it0Z4VZgEAMF0IRQBMqzMLlNG81/Zery09Tlt7nA5SoEy5VBgXIks7rG5YGiR23iMDkepr7Klm6UYEIQAAACgNznnJxFsxDQx5fbjHaWuP17YeVrJPpTCQOlqNLmu3WjTXaE6zkbU0SwcAFB+hCICiKqwiMcbo+KDX5j1OO/q89hyIQxJ+QE1OTUbqmGnU0WrV1W40r9UoSLgQObPIBAAAAEpd4VrYe6/ew16b97CSPQnWSO0tRpe1Gy2aYzW/zSgM4trDGiZNAQBKB6EIgJJy5gXzyKjXnoNeu/u8dh9w2nPQ68RwsUdYugIrzWoy6miNPxbMsmqqiwsPChEAAADgfOeuZN/V59Vz2Gvf2MeBo/HXcb50KLU2mlOrQbrajTIpw6QpAEDJIxQBUNLOLFIk6egJr53744Ckr99rf7/X8cEiD7IIsmmptcGorTH+mN9q1N4Sz8Q6998MAAAAwPh47+WcFASnJxcdPOrVc8hr35E4KOk97Ktq260wiGuPWY1GbU3xY3uL0Yxc/G/kvJfoCwIAKCOEIgDKTjS25VZh5tHI6FhAciQuWA4eix8PH1fZz+qqzUptjUatDUatjXEBMqvJqDYbf++Fos1aVoEAAAAAU+XcGuTEsFfvoTNWlYzVIuVcfwRWmlkIP8bqjtnNRo21p2uNKPLUHgCAskcoAqBiRC5u8F2YoeSc18CwdOyEV/8J6dig17ETXscGxz4fjD/PR8UZby4jNdQazchJM2qNGnJGM2rj5xprjepzUjok/AAAAABK0bmrSpzzGjopDQx5HT0hHR/yGhg6/Tgw5E99PjI6feNMhfFkq1zGqDYr1WbNeX9uazRqqjtdS51bWwEAUEkIRQBUBee8vFc8u+ucC/uRUa+R0bHHk9LwqDR88vTzJ0el4VF/Vnhy1hnM2Z+mQimTMsqkpExKyqaMshmpJn36+XTq7O2tCgWVDNteAQAAAOWusKWtvGTs+f018lHcL/H42ESt40NeJ/OSc1Lk4lAiiqTIn37OKK5njDnncxNvcXVmyFFfI+WyRrmMFAbn1xfOxeOLV78w8QoAUF0IRQDgApyPQxTvxzKPsWJD4/iJ6XX2/0eRAQAAAOBiChOkvM6Yb2XOeDBnT8ryp/5zxp8LnzDJCgCAj0UoAgAAAAAAAAAAqoIt9gAAAAAAAAAAAACmA6EIAAAAAAAAAACoCoQiAAAAAAAAAACgKhCKAAAAAAAAAACAqkAoAgAAAAAAAAAAqgKhCAAAAAAAAAAAqAqEIgAAAAAAAAAAoCoQigAAAAAAAAAAgKpAKAIAAAAAAAAAAKoCoQgAAAAAAAAAAKgKhCIAAAAAAAAAAKAqEIoAAAAAAAAAAICqQCgCAAAAAAAAAACqAqEIAAAAAAAAAACoCoQiAAAAAAAAAACgKhCKAAAAAAAAAACAqkAoAgAAAAAAAAAAqgKhCAAAAAAAAAAAqAqEIgAAAAAAAAAAoCoQigAAAAAAAAAAgKpAKAIAAAAAAAAAAKoCoQgAAAAAAAAAAKgKhCIAAAAAAAAAAKAqEIoAAAAAAAAAAICqQCgCAAAAAAAAAACqAqEIAAAAAAAAAACoCoQiAAAAAAAAAACgKvx/8zrCuFdeHLoAAAAASUVORK5CYII=", "text/plain": [ - "
" + "40012" + ] + }, + "execution_count": 21, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "len(train)" + ] + }, + { + "cell_type": "code", + "execution_count": 23, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "297" + ] + }, + "execution_count": 23, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "len(temp_0)" + ] + }, + { + "cell_type": "code", + "execution_count": 22, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "0.841997400779766" + ] + }, + "execution_count": 22, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "33690/40012" + ] + }, + { + "cell_type": "code", + "execution_count": 16, + "metadata": {}, + "outputs": [ + { + "data": { + "image/png": "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", + "text/plain": [ + "
" ] }, "metadata": {}, @@ -42,21 +218,21 @@ "source": [ "from _analysis import create_pie_chart, plot_heatmap\n", "import matplotlib.pyplot as plt\n", - "temp_0 = templates[0]\n", - "fig, axs = plt.subplots(3, 2, figsize=(16, 14)) # Adjust size as needed\n", + "\n", + "fig, axs = plt.subplots(2, 2, figsize=(16, 10)) # Adjust size as needed\n", "\n", "# Plot the pie chart in the first subplot (top-left)\n", - "create_pie_chart(temp_0, 'Reaction Type', ax=axs[0, 0], title='A. Template library', color_pallet='pastel')\n", + "create_pie_chart(temp_0, 'Reaction Type', ax=axs[0, 1], title='B. Template library', color_pallet='pastel')\n", "\n", - "create_pie_chart(data_cluster, 'Reaction Type', ax=axs[0, 1], title= 'B. Database', color_pallet='pastel')\n", + "create_pie_chart(data_cluster, 'Reaction Type', ax=axs[0, 0], title= 'A. Database', color_pallet='pastel')\n", "\n", - "create_pie_chart(temp_0, 'Topo Type', ax=axs[1, 0], title='C. Template library', color_pallet='coolwarm')\n", + "create_pie_chart(temp_0, 'Topo Type', ax=axs[1, 1], title='D. Template library', color_pallet='coolwarm')\n", "\n", - "create_pie_chart(data_cluster, 'Topo Type', ax=axs[1, 1], title='D. Database', color_pallet='coolwarm')\n", + "create_pie_chart(data_cluster, 'Topo Type', ax=axs[1, 0], title='C. Database', color_pallet='coolwarm')\n", "\n", - "create_pie_chart(temp_0, 'Reaction Step', ax=axs[2, 0], title='E. Template library', color_pallet='coolwarm')\n", + "# create_pie_chart(temp_0, 'Reaction Step', ax=axs[2, 0], title='E. Template library', color_pallet='coolwarm')\n", "\n", - "create_pie_chart(data_cluster, 'Reaction Step', ax=axs[2, 1], title='F. Database', color_pallet='coolwarm')\n", + "# create_pie_chart(data_cluster, 'Reaction Step', ax=axs[2, 1], title='F. Database', color_pallet='coolwarm')\n", "\n", "\n", "plt.tight_layout()\n", @@ -66,7 +242,7 @@ }, { "cell_type": "code", - "execution_count": 33, + "execution_count": 17, "metadata": {}, "outputs": [ { @@ -75,13 +251,13 @@ "" ] }, - "execution_count": 33, + "execution_count": 17, "metadata": {}, "output_type": "execute_result" }, { "data": { - "image/png": "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", + "image/png": "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", "text/plain": [ "
" ] @@ -94,6 +270,36 @@ "create_pie_chart(data_cluster, 'Reaction Step', ax=None, title='D. Database', color_pallet='coolwarm')" ] }, + { + "cell_type": "code", + "execution_count": 18, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "" + ] + }, + "execution_count": 18, + "metadata": {}, + "output_type": "execute_result" + }, + { + "data": { + "image/png": "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", + "text/plain": [ + "
" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "create_pie_chart(, 'Reaction Step', ax=None, title='D. Database', color_pallet='coolwarm')" + ] + }, { "cell_type": "markdown", "metadata": {}, @@ -103,7 +309,7 @@ }, { "cell_type": "code", - "execution_count": 4, + "execution_count": 13, "metadata": {}, "outputs": [], "source": [ @@ -112,7 +318,7 @@ }, { "cell_type": "code", - "execution_count": 5, + "execution_count": 14, "metadata": {}, "outputs": [], "source": [ @@ -124,7 +330,7 @@ }, { "cell_type": "code", - "execution_count": 6, + "execution_count": 15, "metadata": {}, "outputs": [], "source": [ @@ -136,7 +342,7 @@ }, { "cell_type": "code", - "execution_count": 18, + "execution_count": 16, "metadata": {}, "outputs": [], "source": [ @@ -149,46 +355,46 @@ }, { "cell_type": "code", - "execution_count": 19, + "execution_count": 25, "metadata": {}, "outputs": [ { "name": "stderr", "output_type": "stream", "text": [ - "/tmp/ipykernel_2863218/440478720.py:71: FutureWarning: \n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:173: FutureWarning: \n", "\n", "Passing `palette` without assigning `hue` is deprecated and will be removed in v0.14.0. Assign the `x` variable to `hue` and set `legend=False` for the same effect.\n", "\n", " sns.barplot(ax=ax, x=types_of_rules, y=percentages, palette=color_pallet)\n", - "/tmp/ipykernel_2863218/440478720.py:78: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:180: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", " ax.set_xticklabels(ax.get_xticklabels(), rotation=45, ha=\"right\")\n", - "/tmp/ipykernel_2863218/440478720.py:71: FutureWarning: \n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:173: FutureWarning: \n", "\n", "Passing `palette` without assigning `hue` is deprecated and will be removed in v0.14.0. Assign the `x` variable to `hue` and set `legend=False` for the same effect.\n", "\n", " sns.barplot(ax=ax, x=types_of_rules, y=percentages, palette=color_pallet)\n", - "/tmp/ipykernel_2863218/440478720.py:78: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:180: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", " ax.set_xticklabels(ax.get_xticklabels(), rotation=45, ha=\"right\")\n", - "/tmp/ipykernel_2863218/440478720.py:71: FutureWarning: \n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:173: FutureWarning: \n", "\n", "Passing `palette` without assigning `hue` is deprecated and will be removed in v0.14.0. Assign the `x` variable to `hue` and set `legend=False` for the same effect.\n", "\n", " sns.barplot(ax=ax, x=types_of_rules, y=percentages, palette=color_pallet)\n", - "/tmp/ipykernel_2863218/440478720.py:78: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:180: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", " ax.set_xticklabels(ax.get_xticklabels(), rotation=45, ha=\"right\")\n", - "/tmp/ipykernel_2863218/440478720.py:71: FutureWarning: \n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:173: FutureWarning: \n", "\n", "Passing `palette` without assigning `hue` is deprecated and will be removed in v0.14.0. Assign the `x` variable to `hue` and set `legend=False` for the same effect.\n", "\n", " sns.barplot(ax=ax, x=types_of_rules, y=percentages, palette=color_pallet)\n", - "/tmp/ipykernel_2863218/440478720.py:78: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", + "/homes/biertank/tieu/Documents/Project/TACsy/SynEco/SynTemp/Docs/Analysis/_analysis.py:180: UserWarning: set_ticklabels() should only be used with a fixed number of ticks, i.e. after set_ticks() or using a FixedLocator.\n", " ax.set_xticklabels(ax.get_xticklabels(), rotation=45, ha=\"right\")\n" ] }, { "data": { - "image/png": "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", + "image/png": "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", "text/plain": [ "
" ] @@ -203,10 +409,10 @@ "fig, axs = plt.subplots(2, 2, figsize=(16, 12)) \n", "\n", "\n", - "plot_rules_distribution(element_count, ax=axs[0, 0], title='A. Elementary reactions in templates', color_pallet= 'pastel')\n", - "plot_rules_distribution(element_count_all, ax=axs[0, 1], title='B. Elementary reactions in database', color_pallet= 'pastel')\n", - "plot_rules_distribution(complex_count, ax=axs[1, 0], title='C. Complicated reactions in templates', refinement=True, color_pallet= 'coolwarm')\n", - "plot_rules_distribution(complex_count_all, ax=axs[1, 1], title='C. Complicated reactions in database', refinement=True, color_pallet= 'coolwarm', threshold = 0.3)\n", + "plot_rules_distribution(element_count, ax=axs[0, 1], title='B. Elementary reactions in templates', color_pallet= 'pastel')\n", + "plot_rules_distribution(element_count_all, ax=axs[0, 0], title='A. Elementary reactions in database', color_pallet= 'pastel')\n", + "plot_rules_distribution(complex_count, ax=axs[1, 1], title='D. Complicated reactions in templates', refinement=True, color_pallet= 'coolwarm')\n", + "plot_rules_distribution(complex_count_all, ax=axs[1, 0], title='C. Complicated reactions in database', refinement=True, color_pallet= 'coolwarm', threshold = 0.3)\n", "\n", "\n", "plt.tight_layout()\n", @@ -223,234 +429,18 @@ }, { "cell_type": "code", - "execution_count": 26, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "text/html": [ - "
\n", - "\n", - "\n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - " \n", - "
Cluster_idRCParentPercentageTopo TypeRingsReaction TypeReaction StepHierarchy
00((10, 11, 38, 39), (10, 11, 38, 39), (10, 11, ...[]13(4,)111
11((32, 1, 13, 14), (32, 1, 13, 14), (32, 1, 13,...[]13(4,)111
22((3, 14, 15, 50, 51, 52), (3, 14, 15, 50, 51, ...[]11(4, 4)022
33((21, 28, 29, 36), (21, 28, 29, 36), (21, 28, ...[]13(4,)111
44((17, 19, 14, 15), (17, 19, 14, 15), (17, 19, ...[]13(4,)111
..............................
312312((17, 27, 30, 31), (17, 27, 30, 31), (17, 27, ...[]13(4,)111
313313((1, 3, 5, 27, 28, 29, 30, 31), (1, 3, 5, 27, ...[]11(4, 4)022
314314((2, 3, 5, 8, 10, 20), (2, 3, 5, 8, 10, 20), (...[]12(0, 5)022
315315((36, 37, 6, 7, 19, 21, 27, 28, 29), (36, 37, ...[]11(4, 4, 6)033
316316((2, 3, 4, 5, 10, 11, 12, 21, 22), (2, 3, 4, 5...[]11(4, 6, 8)033
\n", - "

317 rows × 9 columns

\n", - "
" - ], - "text/plain": [ - " Cluster_id RC Parent \\\n", - "0 0 ((10, 11, 38, 39), (10, 11, 38, 39), (10, 11, ... [] \n", - "1 1 ((32, 1, 13, 14), (32, 1, 13, 14), (32, 1, 13,... [] \n", - "2 2 ((3, 14, 15, 50, 51, 52), (3, 14, 15, 50, 51, ... [] \n", - "3 3 ((21, 28, 29, 36), (21, 28, 29, 36), (21, 28, ... [] \n", - "4 4 ((17, 19, 14, 15), (17, 19, 14, 15), (17, 19, ... [] \n", - ".. ... ... ... \n", - "312 312 ((17, 27, 30, 31), (17, 27, 30, 31), (17, 27, ... [] \n", - "313 313 ((1, 3, 5, 27, 28, 29, 30, 31), (1, 3, 5, 27, ... [] \n", - "314 314 ((2, 3, 5, 8, 10, 20), (2, 3, 5, 8, 10, 20), (... [] \n", - "315 315 ((36, 37, 6, 7, 19, 21, 27, 28, 29), (36, 37, ... [] \n", - "316 316 ((2, 3, 4, 5, 10, 11, 12, 21, 22), (2, 3, 4, 5... [] \n", - "\n", - " Percentage Topo Type Rings Reaction Type Reaction Step Hierarchy \n", - "0 1 3 (4,) 1 1 1 \n", - "1 1 3 (4,) 1 1 1 \n", - "2 1 1 (4, 4) 0 2 2 \n", - "3 1 3 (4,) 1 1 1 \n", - "4 1 3 (4,) 1 1 1 \n", - ".. ... ... ... ... ... ... \n", - "312 1 3 (4,) 1 1 1 \n", - "313 1 1 (4, 4) 0 2 2 \n", - "314 1 2 (0, 5) 0 2 2 \n", - "315 1 1 (4, 4, 6) 0 3 3 \n", - "316 1 1 (4, 6, 8) 0 3 3 \n", - "\n", - "[317 rows x 9 columns]" - ] - }, - "execution_count": 26, - "metadata": {}, - "output_type": "execute_result" - } - ], + "outputs": [], "source": [ "df" ] }, { "cell_type": "code", - "execution_count": 31, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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", - "text/plain": [ - "
" - ] - }, - "metadata": {}, - "output_type": "display_data" - } - ], + "outputs": [], "source": [ "import pandas as pd\n", "import seaborn as sns\n", @@ -504,29 +494,9 @@ }, { "cell_type": "code", - "execution_count": 24, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "text/plain": [ - "{'Cluster_id': 0,\n", - " 'RC': (,\n", - " ,\n", - " ),\n", - " 'Parent': [],\n", - " 'Percentage': 6.37,\n", - " 'Topo Type': 'Single Cyclic',\n", - " 'Rings': [4],\n", - " 'Reaction Type': 'Elementary',\n", - " 'Reaction Step': 1}" - ] - }, - "execution_count": 24, - "metadata": {}, - "output_type": "execute_result" - } - ], + "outputs": [], "source": [ "temp_0[0]" ] @@ -550,20 +520,71 @@ }, { "cell_type": "code", - "execution_count": 12, + "execution_count": 19, "metadata": {}, "outputs": [ { "data": { - "image/png": "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", "text/plain": [ - "
" + "1373.238" ] }, + "execution_count": 19, "metadata": {}, - "output_type": "display_data" + "output_type": "execute_result" + } + ], + "source": [ + "from datetime import datetime\n", + "\n", + "# Define the two timestamps\n", + "timestamp1 = \"2024-07-22 09:45:52,500\"\n", + "timestamp2 = \"2024-07-22 10:08:45,738\"\n", + "\n", + "# Convert the strings to datetime objects\n", + "format_str = \"%Y-%m-%d %H:%M:%S,%f\"\n", + "time1 = datetime.strptime(timestamp1, format_str)\n", + "time2 = datetime.strptime(timestamp2, format_str)\n", + "\n", + "# Calculate the difference in seconds\n", + "difference = (time2 - time1).total_seconds()\n", + "difference\n" + ] + }, + { + "cell_type": "code", + "execution_count": 21, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "0.03432065380385885" + ] + }, + "execution_count": 21, + "metadata": {}, + "output_type": "execute_result" } ], + "source": [ + "1373.238/40012" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [ + "0.034" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], "source": [ "import matplotlib.pyplot as plt\n", "import numpy as np\n", @@ -624,20 +645,9 @@ }, { "cell_type": "code", - "execution_count": 63, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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", - "text/plain": [ - "
" - ] - }, - "metadata": {}, - "output_type": "display_data" - } - ], + "outputs": [], "source": [ "import matplotlib.pyplot as plt\n", "import numpy as np\n", @@ -696,20 +706,9 @@ }, { "cell_type": "code", - "execution_count": 65, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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", - "text/plain": [ - "
" - ] - }, - "metadata": {}, - "output_type": "display_data" - } - ], + "outputs": [], "source": [ "import matplotlib.pyplot as plt\n", "import seaborn as sns\n", @@ -762,20 +761,9 @@ }, { "cell_type": "code", - "execution_count": 67, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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", - "text/plain": [ - "
" - ] - }, - "metadata": {}, - "output_type": "display_data" - } - ], + "outputs": [], "source": [ "# Example usage\n", "fig, axes = plt.subplots(1, 2, figsize=(14, 6))\n", @@ -803,7 +791,7 @@ }, { "cell_type": "code", - "execution_count": 1, + "execution_count": null, "metadata": {}, "outputs": [], "source": [ @@ -815,7421 +803,16 @@ }, { "cell_type": "code", - "execution_count": 7, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "text/plain": [ - "[{'R-id': 0,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 1,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 2,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 3,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 4,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 5,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 6,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 7,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 8,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 9,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 15,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 1,\n", - " 'Cluster_R3': 1,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 16,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 17,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 18,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 3,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 19,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 3,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 20,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 22,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 23,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 24,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 25,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 26,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 27,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 28,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 29,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 30,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 31,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 32,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 33,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 34,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 35,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 36,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 37,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 8,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 38,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 8,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 39,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 41,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 42,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 43,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 44,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 45,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 46,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 47,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 48,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 49,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 50,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 51,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 52,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 53,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 54,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 55,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 56,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 57,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 58,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 59,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 60,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 10,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 61,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 62,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 63,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 64,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 65,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 66,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 67,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 68,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 69,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 70,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 71,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 72,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 73,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 74,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 75,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 76,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 77,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 15,\n", - " 'Cluster_R3': 37,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 78,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 15,\n", - " 'Cluster_R3': 37,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 79,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 80,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 81,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 82,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 83,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 39,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 84,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 18,\n", - " 'Cluster_R3': 42,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 85,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 86,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 87,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 88,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 89,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 19,\n", - " 'Cluster_R3': 43,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 90,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 20,\n", - " 'Cluster_R3': 44,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 91,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 21,\n", - " 'Cluster_R3': 45,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 92,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 93,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 94,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 95,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 96,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 97,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 98,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 99,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 100,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 101,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 102,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 103,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 46,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 104,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 105,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 106,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 107,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 108,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 109,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 110,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 111,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 112,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 113,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 114,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 115,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 116,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 117,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 118,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 119,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 120,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 121,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 122,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 123,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 124,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 125,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 126,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 127,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 128,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 129,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 130,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 131,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 132,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 133,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 134,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 39,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 135,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 136,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 137,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 138,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 139,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 140,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 141,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 142,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 143,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 144,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 145,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 146,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 6,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 147,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 6,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 148,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 149,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 150,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 151,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 152,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 153,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 154,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 155,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 156,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 157,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 158,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 159,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 47,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 160,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 47,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 163,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 164,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 165,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 166,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 167,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 168,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 169,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 170,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 171,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 172,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 173,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 174,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 175,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 176,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 177,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 178,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 179,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 180,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 181,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 182,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 183,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 184,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 185,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 186,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 187,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 188,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 189,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 190,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 191,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 192,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 193,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 198,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 199,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 200,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 201,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 202,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 203,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 204,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 205,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 206,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 207,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 208,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 209,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 210,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 211,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 212,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 213,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 214,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 215,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 216,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 217,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 218,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 219,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 220,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 221,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 222,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 223,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 224,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 225,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 226,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 227,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 228,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 229,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 230,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 231,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 41,\n", - " 'Cluster_R3': 52,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 232,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 233,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 33,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 234,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 235,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 236,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 237,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 9,\n", - " 'Cluster_R3': 53,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 238,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 239,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 15,\n", - " 'Cluster_R3': 37,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 240,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 241,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 3,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 242,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 17,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 243,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 245,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 18,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 246,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 18,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 247,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 34,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 248,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 249,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 250,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 251,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 252,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 253,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 254,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 256,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 257,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 258,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 259,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 261,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 262,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 263,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 265,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 266,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 267,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 268,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 269,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 270,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 43,\n", - " 'Cluster_R3': 55,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 43,\n", - " 'Cluster_R3': 55,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 43,\n", - " 'Cluster_R3': 55,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 44,\n", - " 'Cluster_R3': 56,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 273,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 274,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 10,\n", - " 'Cluster_R3': 57,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 275,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 24,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 277,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 278,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 279,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 280,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 281,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 282,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 283,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 284,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 285,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 8,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 286,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 287,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 288,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 289,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 291,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 22,\n", - " 'Cluster_R3': 58,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 292,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 22,\n", - " 'Cluster_R3': 58,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 293,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 294,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 295,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 23,\n", - " 'Cluster_R3': 59,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 296,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 297,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 298,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 299,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 300,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 301,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 24,\n", - " 'Cluster_R3': 60,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 302,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 303,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 11,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 304,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 28,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 306,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 12,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 307,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 308,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 18,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 309,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 25,\n", - " 'Cluster_R3': 61,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 311,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 3,\n", - " 'Cluster_R2': 45,\n", - " 'Cluster_R3': 63,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 312,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 24,\n", - " 'Cluster_R3': 60,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 312,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 24,\n", - " 'Cluster_R3': 60,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 313,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 25,\n", - " 'Cluster_R3': 61,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 314,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 315,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 41,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 316,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 46,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 317,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 319,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 320,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 13,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 321,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 26,\n", - " 'Cluster_R3': 64,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 322,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 65,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 323,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 67,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 324,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 325,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 25,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 326,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 327,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 29,\n", - " 'Cluster_R3': 70,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 328,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 29,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 329,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 330,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 30,\n", - " 'Cluster_R3': 71,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 331,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 332,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 333,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 334,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 35,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 335,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 65,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 336,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 65,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 337,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 338,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 339,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 34,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 339,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 36,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 340,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 66,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 341,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 32,\n", - " 'Cluster_R3': 73,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 342,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 33,\n", - " 'Cluster_R3': 74,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 342,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 343,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 344,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 345,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 346,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 3,\n", - " 'Cluster_R2': 45,\n", - " 'Cluster_R3': 63,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 347,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 348,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 35,\n", - " 'Cluster_R3': 76,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 349,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 350,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 351,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 352,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 353,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 354,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 355,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 356,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 33,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 357,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 359,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 360,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 361,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 362,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 363,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 364,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 365,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 366,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 367,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 368,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 369,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 33,\n", - " 'Cluster_R3': 74,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 370,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 33,\n", - " 'Cluster_R3': 74,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 371,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 36,\n", - " 'Cluster_R3': 77,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 372,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 373,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 374,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 375,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 36,\n", - " 'Cluster_R3': 78,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 377,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 378,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 37,\n", - " 'Cluster_R3': 79,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 379,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 380,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 23,\n", - " 'Cluster_R3': 59,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 381,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 382,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 383,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 384,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 385,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 386,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 387,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 388,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 3,\n", - " 'Cluster_R2': 45,\n", - " 'Cluster_R3': 63,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 389,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 390,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 391,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 9,\n", - " 'Cluster_R3': 54,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 392,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 393,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 394,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 395,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 42,\n", - " 'Cluster_R3': 80,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 396,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 397,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 398,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 405,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 407,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 408,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 409,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 410,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 411,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 1,\n", - " 'Cluster_R3': 1,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 412,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 68,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 413,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 69,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 414,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 67,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 415,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 67,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 416,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 41,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 417,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 418,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 419,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 420,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 421,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 422,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 423,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 38,\n", - " 'Cluster_R3': 81,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 424,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 38,\n", - " 'Cluster_R3': 81,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 424,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 38,\n", - " 'Cluster_R3': 81,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 425,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 39,\n", - " 'Cluster_R3': 82,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 426,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 39,\n", - " 'Cluster_R3': 82,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 426,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 39,\n", - " 'Cluster_R3': 82,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 427,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 25,\n", - " 'Cluster_R3': 62,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 428,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 429,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 20,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 430,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 21,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 431,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 432,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 14,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 433,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 434,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 435,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 436,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 437,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 437,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 438,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 439,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 440,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 441,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 442,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 443,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 444,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 445,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 446,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 447,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 448,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 449,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 450,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 451,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 452,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 453,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 454,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 455,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 456,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 457,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 458,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 459,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 460,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 461,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 462,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 463,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 464,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 465,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 466,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 467,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 468,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 469,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 470,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 471,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 472,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 473,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 474,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 475,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 476,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 477,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 478,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 479,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 480,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 481,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 482,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 483,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 484,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 485,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 486,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 487,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 488,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 489,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 490,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 491,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 492,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 493,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 494,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 495,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 496,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 497,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 498,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 499,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 500,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 501,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 502,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 503,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 504,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 505,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 506,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 507,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 508,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 509,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 510,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 511,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 512,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 513,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 514,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 515,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2}]" - ] - }, - "execution_count": 7, - "metadata": {}, - "output_type": "execute_result" - } - ], + "outputs": [], "source": [ "data" ] }, { "cell_type": "code", - "execution_count": 2, + "execution_count": null, "metadata": {}, "outputs": [], "source": [ @@ -8251,21 +834,9 @@ }, { "cell_type": "code", - "execution_count": 6, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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", - "text/plain": [ - "
" - ] - }, - "execution_count": 6, - "metadata": {}, - "output_type": "execute_result" - } - ], + "outputs": [], "source": [ "from SynTemp.SynVis.chemical_graph_visualizer import ChemicalGraphVisualizer\n", "\n", @@ -8275,7 +846,7 @@ }, { "cell_type": "code", - "execution_count": 13, + "execution_count": null, "metadata": {}, "outputs": [], "source": [ @@ -8284,19 +855,9 @@ }, { "cell_type": "code", - "execution_count": 18, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "name": "stderr", - "output_type": "stream", - "text": [ - "[Parallel(n_jobs=4)]: Using backend LokyBackend with 4 concurrent workers.\n", - "[Parallel(n_jobs=4)]: Done 282 tasks | elapsed: 0.2s\n", - "[Parallel(n_jobs=4)]: Done 493 out of 493 | elapsed: 0.3s finished\n" - ] - } - ], + "outputs": [], "source": [ "from SynTemp.SynRule.rule_writing import RuleWriting\n", "write = RuleWriting()\n", @@ -8312,7 +873,7 @@ }, { "cell_type": "code", - "execution_count": 8, + "execution_count": null, "metadata": {}, "outputs": [], "source": [ @@ -8322,7434 +883,18 @@ }, { "cell_type": "code", - "execution_count": 3, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "text/plain": [ - "493" - ] - }, - "execution_count": 3, - "metadata": {}, - "output_type": "execute_result" - } - ], + "outputs": [], "source": [ "len(data)" ] }, { "cell_type": "code", - "execution_count": 7, + "execution_count": null, "metadata": {}, - "outputs": [ - { - "data": { - "text/plain": [ - "[{'R-id': 0,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 1,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 2,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 3,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 4,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 5,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 6,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 7,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 8,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 9,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 15,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 1,\n", - " 'Cluster_R3': 1,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 16,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 17,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 18,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 3,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 19,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 3,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 20,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 22,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 23,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 24,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 25,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 26,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 27,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 28,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 29,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 30,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 31,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 32,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 33,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 34,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 35,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 36,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 37,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 8,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 38,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 8,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 39,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 41,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 42,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 43,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 44,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 45,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 46,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 47,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 48,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 49,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 50,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 51,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 52,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 53,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 54,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 55,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 56,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 57,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 58,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 59,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 60,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 10,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 61,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 62,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 63,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 64,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 65,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 66,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 67,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 68,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 69,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 70,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 71,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 72,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 73,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 74,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 75,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 76,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 77,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 15,\n", - " 'Cluster_R3': 37,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 78,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 15,\n", - " 'Cluster_R3': 37,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 79,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 80,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 81,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 82,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 83,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 39,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 84,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 18,\n", - " 'Cluster_R3': 42,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 85,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 86,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 87,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 88,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 89,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 19,\n", - " 'Cluster_R3': 43,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 90,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 20,\n", - " 'Cluster_R3': 44,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 91,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 21,\n", - " 'Cluster_R3': 45,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 92,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 93,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 94,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 95,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 96,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 97,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 98,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 99,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 100,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 101,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 102,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 103,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 46,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 104,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 105,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 106,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 107,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 108,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 109,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 110,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 111,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 112,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 113,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 114,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 115,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 116,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 48,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 117,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 118,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 119,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 120,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 121,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 122,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 123,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 124,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 125,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 126,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 127,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 128,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 129,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 130,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 131,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 132,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 133,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 0,\n", - " 'Cluster_R3': 0,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 134,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 39,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 135,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 136,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 137,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 138,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 139,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 140,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 141,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 142,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 143,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 144,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 145,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 146,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 6,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 147,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 6,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 148,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 149,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 150,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 151,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 152,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 153,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 154,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 155,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 156,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 157,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 158,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 159,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 47,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 160,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 47,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 163,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 164,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 165,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 166,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 167,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 168,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 169,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 170,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 171,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 172,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 173,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 174,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 175,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 176,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 177,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 178,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 179,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 180,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 181,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 182,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 183,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 184,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 185,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 186,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 187,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 188,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 189,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 190,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 191,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 192,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 193,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 198,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 199,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 200,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 201,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 8,\n", - " 'Cluster_R3': 51,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 202,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 203,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 204,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 205,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 206,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 207,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 208,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 50,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 209,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 210,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 211,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 212,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 213,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 214,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 215,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 216,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 217,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 218,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 219,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 220,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 221,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 222,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 223,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 224,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 225,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 226,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 227,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 228,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 229,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 230,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 23,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 231,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 41,\n", - " 'Cluster_R3': 52,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 232,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 233,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 33,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 234,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 235,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 236,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 237,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 9,\n", - " 'Cluster_R3': 53,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 238,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 239,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 15,\n", - " 'Cluster_R3': 37,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 240,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 241,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 3,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 242,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 17,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 243,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 245,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 18,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 246,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 18,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 247,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 34,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 248,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 249,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 250,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 251,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 252,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 253,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 254,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 256,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 257,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 258,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 259,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 261,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 262,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 263,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 265,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 266,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 267,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 268,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 269,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 270,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 43,\n", - " 'Cluster_R3': 55,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 43,\n", - " 'Cluster_R3': 55,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 43,\n", - " 'Cluster_R3': 55,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 272,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 2,\n", - " 'Cluster_R1': 4,\n", - " 'Cluster_R2': 44,\n", - " 'Cluster_R3': 56,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 3},\n", - " {'R-id': 273,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 274,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 10,\n", - " 'Cluster_R3': 57,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 275,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 24,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 277,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 40,\n", - " 'Cluster_R3': 26,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 278,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 279,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 280,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 281,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 282,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 30,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 283,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 284,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 285,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 8,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 286,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 287,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 288,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 289,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 291,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 22,\n", - " 'Cluster_R3': 58,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 292,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 22,\n", - " 'Cluster_R3': 58,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 293,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 294,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 295,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 23,\n", - " 'Cluster_R3': 59,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 296,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 297,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 298,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 299,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 300,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 19,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 301,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 24,\n", - " 'Cluster_R3': 60,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 302,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 303,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 11,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 304,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 28,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 306,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 12,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 307,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 15,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 308,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 18,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 309,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 25,\n", - " 'Cluster_R3': 61,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 311,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 3,\n", - " 'Cluster_R2': 45,\n", - " 'Cluster_R3': 63,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 312,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 24,\n", - " 'Cluster_R3': 60,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 312,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 24,\n", - " 'Cluster_R3': 60,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 313,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 25,\n", - " 'Cluster_R3': 61,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 314,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 315,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 41,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 316,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 6,\n", - " 'Cluster_R3': 46,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 317,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 319,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 320,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 13,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 321,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 26,\n", - " 'Cluster_R3': 64,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 322,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 65,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 323,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 67,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 324,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 325,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 25,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 326,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 327,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 29,\n", - " 'Cluster_R3': 70,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 328,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 29,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 329,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 330,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 30,\n", - " 'Cluster_R3': 71,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 331,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 332,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 333,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 334,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 35,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 335,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 65,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 336,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 65,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 337,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 338,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 339,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 34,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 339,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 36,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 340,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 27,\n", - " 'Cluster_R3': 66,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 341,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 32,\n", - " 'Cluster_R3': 73,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 342,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 33,\n", - " 'Cluster_R3': 74,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 342,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 343,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 16,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 344,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 345,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 346,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 3,\n", - " 'Cluster_R2': 45,\n", - " 'Cluster_R3': 63,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 347,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 348,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 35,\n", - " 'Cluster_R3': 76,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 349,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 5,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 350,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 351,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 352,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 353,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 354,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 355,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 356,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 33,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 357,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 359,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 360,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 361,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 362,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 363,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 364,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 365,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 366,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 367,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 368,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 369,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 33,\n", - " 'Cluster_R3': 74,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 370,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 33,\n", - " 'Cluster_R3': 74,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 371,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 36,\n", - " 'Cluster_R3': 77,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 372,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 373,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 374,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 375,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 36,\n", - " 'Cluster_R3': 78,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 377,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 378,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 37,\n", - " 'Cluster_R3': 79,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 379,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 31,\n", - " 'Cluster_R3': 72,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 380,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 23,\n", - " 'Cluster_R3': 59,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 381,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 382,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 383,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 384,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 385,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 386,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 387,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 388,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 3,\n", - " 'Cluster_R2': 45,\n", - " 'Cluster_R3': 63,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 389,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 390,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 5,\n", - " 'Cluster_R3': 22,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 391,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 9,\n", - " 'Cluster_R3': 54,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 392,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 393,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 394,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 395,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 1,\n", - " 'Cluster_R1': 2,\n", - " 'Cluster_R2': 42,\n", - " 'Cluster_R3': 80,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 396,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 397,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 398,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 9,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 405,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 407,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 4,\n", - " 'Cluster_R3': 7,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 408,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 409,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 7,\n", - " 'Cluster_R3': 49,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 410,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 3,\n", - " 'Cluster_R3': 4,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 411,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 1,\n", - " 'Cluster_R3': 1,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 412,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 68,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 413,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 69,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 414,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 67,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 415,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 28,\n", - " 'Cluster_R3': 67,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 416,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 41,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 417,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 418,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 419,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 420,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 421,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 422,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 423,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 38,\n", - " 'Cluster_R3': 81,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 424,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 38,\n", - " 'Cluster_R3': 81,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 424,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 38,\n", - " 'Cluster_R3': 81,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 425,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 39,\n", - " 'Cluster_R3': 82,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 426,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 39,\n", - " 'Cluster_R3': 82,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 426,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 39,\n", - " 'Cluster_R3': 82,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 427,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 25,\n", - " 'Cluster_R3': 62,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 428,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 32,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 429,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 20,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 430,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 12,\n", - " 'Cluster_R3': 21,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 431,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 432,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 11,\n", - " 'Cluster_R3': 14,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 433,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 17,\n", - " 'Cluster_R3': 40,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 434,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 435,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 436,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 437,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 437,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 0,\n", - " 'Cluster_R2': 2,\n", - " 'Cluster_R3': 2,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 438,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 439,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 440,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 441,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 442,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 443,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 444,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 445,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 446,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 447,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 448,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 449,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 450,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 451,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 452,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 453,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 454,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 455,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 456,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 457,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 458,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 459,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 460,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 461,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 462,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 463,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 16,\n", - " 'Cluster_R3': 38,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 464,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 465,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 466,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 467,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 468,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 469,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 470,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 471,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 472,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 473,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 474,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 475,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 476,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 477,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 14,\n", - " 'Cluster_R3': 31,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 478,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 479,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 480,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 481,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 482,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 483,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 484,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 485,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 486,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 487,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 488,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 489,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 490,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 491,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 492,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 493,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 494,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 495,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 496,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 497,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 498,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 499,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 500,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 501,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 502,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 503,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 504,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 505,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 506,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 507,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 508,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 509,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 510,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 511,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 512,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 13,\n", - " 'Cluster_R3': 27,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 513,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 514,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2},\n", - " {'R-id': 515,\n", - " 'ITSGraph': (,\n", - " ,\n", - " ),\n", - " 'GraphRules': (,\n", - " ,\n", - " ),\n", - " 'Cluster_R0': 0,\n", - " 'Cluster_R1': 1,\n", - " 'Cluster_R2': 34,\n", - " 'Cluster_R3': 75,\n", - " 'Topo Type': 'Complex Cyclic',\n", - " 'Rings': [0, 6],\n", - " 'Reaction Type': 'Complicated',\n", - " 'Reaction Step': 2}]" - ] - }, - "execution_count": 7, - "metadata": {}, - "output_type": "execute_result" - } - ], + "outputs": [], "source": [ "data" ] diff --git a/SynTemp/SynITS/its_refinement.py b/SynTemp/SynITS/its_refinement.py index bb07853..931f232 100644 --- a/SynTemp/SynITS/its_refinement.py +++ b/SynTemp/SynITS/its_refinement.py @@ -55,7 +55,7 @@ def process_dict( graph_data[column][1], graph_data[column][2], extend=False, - n_knn=1, + n_knn=0, ) if len(rc.edges) > 20: return None @@ -64,7 +64,7 @@ def process_dict( ) uncertain_graph.append(processed_data) results.append(type_of_graph) - if type_of_graph == "Topo Cyclic": + if type_of_graph == "Single Cyclic": processed_data["R-id"] = input_graph.get("R-id", "") return processed_data except ValueError: diff --git a/SynTemp/__main__.py b/SynTemp/__main__.py index 49b76e4..2a594be 100644 --- a/SynTemp/__main__.py +++ b/SynTemp/__main__.py @@ -38,7 +38,7 @@ def parse_arguments(): "--fix_hydrogen", action="store_true", help="Enable fixing hydrogen" ) parser.add_argument( - "--refinement_its", action="store_false", help="Refine non-equivalent ITS" + "--refinement_its", action="store_true", help="Refine non-equivalent ITS" ) parser.add_argument( "--rerun_aam", action="store_true", help="Run AAM based on mapper types input"