diff --git a/requirements.txt b/requirements.txt
index b1fc2207d8..291faa7bdc 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -7,7 +7,7 @@ mypy-extensions
 psutil>=5.6.6
 importlib_resources>=1.4;python_version<'3.9'
 coloredlogs
-pydot>=1.4.1,<3
+pydot>=1.4.1,<4
 argcomplete>=1.12.0
 pyparsing!=3.0.2  # breaks --print-dot (pydot) https://github.com/pyparsing/pyparsing/issues/319
 cwl-utils>=0.32
diff --git a/setup.py b/setup.py
index 9ab4f240ea..2850eb1a3e 100644
--- a/setup.py
+++ b/setup.py
@@ -132,7 +132,7 @@
         "psutil >= 5.6.6",
         "importlib_resources>=1.4;python_version<'3.9'",
         "coloredlogs",
-        "pydot >= 1.4.1, <3",
+        "pydot >= 1.4.1, < 4",
         "argcomplete >= 1.12.0",
         "pyparsing != 3.0.2",  # breaks --print-dot (pydot) https://github.com/pyparsing/pyparsing/issues/319
         "cwl-utils >= 0.32",