wordpress-4-supercache.conf

root /home/u1/domains/example.com;

set $cache_uri $request_uri;

if ($request_method = POST) {
  set $cache_uri 'null cache';
}

if ($query_string != "") {
  set $cache_uri 'null cache';
}

if ($request_uri ~* "(/wp-admin/|/xmlrpc.php|/wp-(app|cron|login|register|mail).php|wp-.*.php|/feed/|index.php|wp-comments-popup.php|wp-links-opml.php|wp-locations.php|sitemap(_index)?.xml|[a-z0-9_-]+-sitemap([0-9]+)?.xml)") {
  set $cache_uri 'null cache';
}

if ($http_cookie ~* "comment_author|wordpress_[a-f0-9]+|wp-postpass|wordpress_logged_in") {
  set $cache_uri 'null cache';
}

location ~ /\. {
  deny all;
}

location = /favicon.ico {
  log_not_found off;
  access_log off;
}

location = /robots.txt {
  allow all;
  log_not_found off;
  access_log off;
}

location / {
  try_files /wp-content/cache/supercache/$http_host/$cache_uri/index.html $uri $uri/ /index.php?$query_string;
}

location ~ ^/wp-admin/includes/ {
  deny all;
}

location ~* /wp-includes/js/tinymce/wp-tinymce.php {
  allow all;
  include fastcgi.conf;
  fastcgi_intercept_errors on;
  fastcgi_pass unix:/var/run/php5-example.com.sock;
}

location ~* /wp-includes/.*\.(php|php3|php4|php5|php6|phps|phtml)$ {
  deny all;
}

location ~* /wp-content/.*\.(php|php3|php4|php5|php6|phps|phtml)$ {
  deny all;
}

location ~* /modules/.*\.(php|php3|php4|php5|php6|phps|phtml)$ {
  deny all;
}

location ~* /skins/.*\.(php|php3|php4|php5|php6|phps|phtml)$ {
  deny all;
}

location = /xmlrpc.php {
  deny all;
}

location ~* \.(js|css|png|jpg|jpeg|gif|ico)$ {
  expires max;
  log_not_found off;
}

location ~* /(?:uploads|files)/.*\.(php|php3|php4|php5|php6|phps|phtml)$ {
  deny all;
}

location ~ \.php$ {
  include fastcgi.conf;
  fastcgi_intercept_errors on;
  fastcgi_pass unix:/var/run/php5-example.com.sock;
}