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CONSENT on clustered cDNA with small Window Size #30

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jkbenotmane opened this issue Aug 19, 2021 · 0 comments
Closed

CONSENT on clustered cDNA with small Window Size #30

jkbenotmane opened this issue Aug 19, 2021 · 0 comments

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@jkbenotmane
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Hi after reconsidering CONSENT-correct,

wouldn´t it make sense to use it with a small clustered Reads from a Clustering Algorithm (e.g. isONClust, RATTLE) and then correct the Reads using a small Windowsize to retain highly variable Splice Junctions?

Trying that approch gave me considerable Results but I couldn´t lower the window Size lower then 70.
Might this be related to Computation Power (I am trying it on Laptop with 64Gb Ram) or might there be a deeper Reason?

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