Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Annotate runs of homozygosity #22

Open
pasted opened this issue Jul 25, 2017 · 0 comments
Open

Annotate runs of homozygosity #22

pasted opened this issue Jul 25, 2017 · 0 comments

Comments

@pasted
Copy link
Owner

pasted commented Jul 25, 2017

**Additional feature- only used as supporting evidence

Use criteria as follows:
separate VCF into regions of adjacent HMZ calls - allow a certain number of HTZ calls within this block (due to miscalls and random mutations). Annotate and sort these blocks by size, some evidence that recessive disorders linked to largest block.

Look at relatedness metrics

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant