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GO-CAM Model mitotic sister chromatid cohesion GO:0007064 #3774

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ValWood opened this issue Nov 17, 2024 · 4 comments
Open
5 tasks

GO-CAM Model mitotic sister chromatid cohesion GO:0007064 #3774

ValWood opened this issue Nov 17, 2024 · 4 comments

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@ValWood
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ValWood commented Nov 17, 2024

Template for GO-CAM Models

Pathway label:

mitotic sister chromatid cohesion GO:0007064

Noctua:
http://noctua.geneontology.org/workbench/noctua-visual-pathway-editor/?model_id=gomodel%3A67369e7600000120

Pathway summary:
https://docs.google.com/presentation/d/1s6fl7JCkJ6DK8hOzCtoOlFBq-T1Fh9pj_SrADq5qg3I/edit#slide=id.g3140e2d1a64_0_0

Screenshot 2024-11-17 at 16 15 30

Annotations in PomBase (Query):
https://www.pombase.org/results/from/id/e4a53d89-bb11-403b-853c-658a44ed04fd

MIssing from model (Query):
https://www.pombase.org/results/from/id/c10337bf-c8e3-4b98-a9b6-4d9b51cf1758

TO DO

  • Look into more precise localization
  • Integrate missing entities
  • sort GO issues establishment/maintenance/ prophase pathway/ protection during metaphase
  • figure swi6 and naa50
  • is this sororin /NatA interaction conserved?
@ValWood ValWood changed the title GO-AM Model mitotic sister chromatid cohesion GO:0007064 GO-CAM Model mitotic sister chromatid cohesion GO:0007064 Nov 17, 2024
@ValWood
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ValWood commented Nov 17, 2024

Default network

Screenshot 2024-11-17 at 16 19 26

How it should look (not indirect reg between sor1 and wpl1 is missing
Screenshot 2024-11-17 at 16 27 03

@ValWood
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ValWood commented Nov 17, 2024

regulation of sororin
Screenshot 2024-11-17 at 15 25 48

@ValWood
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ValWood commented Nov 17, 2024

Does this happen in yeast?
Screenshot 2024-11-17 at 14 56 30

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ValWood commented Nov 17, 2024

Screenshot 2024-11-17 at 14 46 53

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