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using Unicycler for hybrid metagenomic- A double-edged sword ? #350

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Hedi65 opened this issue Jan 31, 2025 · 0 comments
Open

using Unicycler for hybrid metagenomic- A double-edged sword ? #350

Hedi65 opened this issue Jan 31, 2025 · 0 comments

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@Hedi65
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Hedi65 commented Jan 31, 2025

Hi

Although the Unicycler developer already mentioned that Unicycler is specifically designed for single isolate genome assembly, there are many papers comparing the hybrid metagenomic tools with Unicycler in their benchmarking. I personally did the same and i amazed over metaQuast metrics when i compare the Unicycler with other tools such as OPERA_MS, MetaSPAdes and MetaPlatanus.

I would like to hear the communities expereince with using Unicycler for hybrid metagenomics.

Thanks in advance

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