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research.qmd
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---
title: ""
filters:
- lightbox
lightbox: auto
---
# Research Summary
![](images/image-1730647569.png){fig-align="center" width="750"}
# Platform technologies for genome design and cell construction
- Development of practical synthetic biology technologies for smart genetic circuit and genome synthesis
- Development of DNA design software for high-accuracy DNA assembly
- Development of artificial genome synthesis technology through genome design and modular assembly
- Development of web-based Partbank database and standardization of bio-parts for biofoundry
![](images/Genome_20230511_2.jpg)
# Development of high-throughtput technology
- Development of molecular evolution technologies for industrially applicable enzyme engineering
- Development of high-speed and mass-volume biofoundry technologies to cope with climate change issues emerging as new threats
![](images/HTS_20230512_2.jpg)
# CRISPR technology based biomedical and industrial applications
- Programmed probiotics with genetic circuits for diagnostics and therapeutics of inflammatory bowel disease
- Establishment and applications of CRISPR technology for metabolic engineering
- Development of therapeutic protein secretion system in bacteroides
![](images/ME_20230512_2.jpg)
# In responding to climate change and global warming
- Development of synthetic consortium of methanotrophs and heterotrophs to produce C4-chemicals from methane by mimicking the natural methane ecosystem
- Development of CRISPR system for engineering methanotroph and partner microbe
- Discovery of biological resources degrading PET using genetically encoded biosensors
- Discovery and characterization of novel plastic degrading strains and enzymes
- Mass production of biodegradable plastic monomers using acid-tolerant microorganisms
![](images/Methane_20230511_2.jpg)