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Flow Immunophenotyping with PhenoGraph - Template

Description

This template performs some basic preprocessing, clustering and dimension reduction steps on flow cytometry data.

Steps

  • Preprocessing: channel-specific logicle transformation
  • Clustering using PhenoGraph
  • Dimension Reduction using UMAP
  • Marker enrichment score
  • Cell population (cluster) proportions computation across samples
  • Relevant data visualisations

Requirements

  • An FCS File or a ZIP of multiple FCS files (imported using the "Upload File" button)
  • A Sample Annotation file containing at least two columns: "filename" and "Condition"