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Update VCF filtration and QC #68

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yashpatel6 opened this issue Mar 9, 2022 · 0 comments
Open

Update VCF filtration and QC #68

yashpatel6 opened this issue Mar 9, 2022 · 0 comments
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@yashpatel6
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For the filtration script, it seems like only the last sample is actually processed, so if we input --tumour sample1 --tumour sample2 --tumour sample3, only sample3 is kept. The preceding --tumour inputs are ignored so the script probably will require an update.

Yeah, I've checked the command and it wouldn't work properly. We might want to drop the script and add a simple filtering process using BCF/VCFtools (e.g. https://github.com/uclahs-cds/pipeline-call-sSV/blob/main/pipeline/modules/bcftools.nf) and use RTGtool for QC instead.

Originally posted by @tyamaguchi-ucla in #61 (comment)

@yashpatel6 yashpatel6 self-assigned this Mar 9, 2022
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