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Single-Molecule-Centrifugation

This repository provides the code for the paper, 'Resolving Molecular Heterogeneity with Single-Molecule Centrifugation'.

Description of files:

  • model.py
    • Implementation of Bayesian Nonparametric model described in Section S2
  • 2022-01-26-dirichlet-sampling.ipynb
    • Fitting the model to the collected datasets
  • 2022-02-11-synthetic-datasets.ipynb
    • Testing the Bayesian nonparametric method on artificial datasets (Section S3)
  • data
    • Filtered transition time data