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241015michaelkopke
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stepping on the gas: innocating for a circular bioeconomy
chief innovation officer : michael kopke
lanzatech <- chief officer
1. ability to leverage diverse carbon source
ancient biology -> inhospitable enviroment
biology co2 fixation routes -wood ljungdahl pathway - . high energy efficiency
anaerobic acetogens : wood lfungdahl pathway
- conversion of two molecules of CO OR CO2 TO
- most actegens synthesis acetate as sole product, but some can make other product such as ethanols.
first step toward an industia strain : adaptive lab evolution
next: developing a genetic toolbox -> DNA transfer, genetic part , genetic toools, gene editing.
otimizing strain performance: reverse engineering, multi omics
optimizating strain performance
expanding the product portfolio: metabolic engineering
- production of c3-c4 platform chemicals
enzyme idendification : mining a historic stratin collection
signification variant identify
pathway optimaization optimization : combinationial library
flux optimizting
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