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Bioconductor 3.12

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@lazappi lazappi released this 29 Oct 08:12
  • Add the splatPop simulation. This is a extension to the splat simulation contributed by @azodichr and @davismcc that adds population effects. It allows you to specify relatedness between individuals and generate cell-type specific eQTL effects. (PR #106)
  • Add a batch.rmEffect parameter to the Splat simulation. This allows generation of a paired simulation without any batch effects. (From @daynefiler PR #103)
  • Add a new minimiseSCE() function which can be used to remove unneeded information from simulation output (or any SingleCellExperiment).
  • All simulations now return sparse assay matrices by default when they would be smaller than the equivalent dense matrix. This is controlled by a new sparsify argument.
  • Users will now be automatically prompted to install packages if they try to use a simulation for which the suggested dependencies are not available.