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309 sc2 pc40 #310

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Dec 4, 2024
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3 changes: 1 addition & 2 deletions R/mc6_mthds.R
Original file line number Diff line number Diff line change
Expand Up @@ -47,8 +47,7 @@
#' \item{noise}{Flag series as noisy if the quality of fit as calculated by the root mean square
#' error (rmse) for the series is greater than the cutoff (coff); \eqn{rmse > coff}{rmse > coff}.}
#' \item{border}{Flag series if borderline activity is suspected based on modeled top parameter
#' (top) relative to cutoff (coff); \eqn{|top|<=1.2*coff~or~|top|>=0.8*coff}{|top| <= 1.2(coff) or
#' |top| >= 0.8(coff)}.}
#' (top) relative to cutoff (coff); \eqn{0.8*coff<=|top|<=1.2*coff}.}
#' \item{overfit.hit}{Method not yet updated for tcpl implementation. Flag hit-calls that would
#' get changed after doing the small N correction to the aic values.}
#' \item{efficacy.50}{Flag low efficacy hits if series has an active hit call (hitc >= 0.9) and
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8 changes: 8 additions & 0 deletions R/sc2_mthds.R
Original file line number Diff line number Diff line change
Expand Up @@ -65,6 +65,7 @@
#' \item{pc20}{Add a cutoff value of 20. Typically for percent of control data.}
#' \item{pc25}{Add a cutoff value of 25. Typically for percent of control data.}
#' \item{pc30}{Add a cutoff value of 30. Typically for percent of control data.}
#' \item{pc40}{Add a cutoff value of 40. Typically for percent of control data.}
#' }
#' }
#'
Expand Down Expand Up @@ -251,6 +252,13 @@ sc2_mthds <- function() {
e1 <- bquote(coff <- c(coff, 16))
list(e1)

},

pc40 = function() {

e1 <- bquote(coff <- c(coff, 40))
list(e1)

}
)
}
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3 changes: 1 addition & 2 deletions man/MC6_Methods.Rd

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1 change: 1 addition & 0 deletions man/SC2_Methods.Rd

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3 changes: 1 addition & 2 deletions vignettes/Introduction_Appendices.Rmd
Original file line number Diff line number Diff line change
Expand Up @@ -2212,8 +2212,7 @@ FlagDescription <- c("Flag series if model directionality is questionable, i.e.
square error $(rmse)$ for the series is greater than the cutoff $(coff)$;
$rmse > coff$",
"Flag series if borderline activity is suspected based on modeled top
parameter $(top)$ relative to cutoff $(coff)$; $|top| <= 1.2 * coff$ or
$|top|>= 0.8 * coff$.",
parameter $(top)$ relative to cutoff $(coff)$; $0.8 * coff <= |top| <= 1.2 * coff$",
"Flag series if the average number of replicates per concentration is less than
2; $nrep < 2$.",
"Flag series if 4 concentrations or less were tested; $nconc <= 4$.",
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