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update on latest poster
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agdamsbo committed May 13, 2024
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Binary file added academia/images/esoc2024svd.pdf
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30 changes: 30 additions & 0 deletions academia/references.bib
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Expand Up @@ -41,3 +41,33 @@ @article{liu2021
Subject{\_}term{\_}id: brain-imaging;stroke},
langid = {en}
}

@article{kraglund2018,
title = {Neuroregeneration and Vascular Protection by Citalopram in Acute Ischemic Stroke (TALOS)},
author = {Kraglund, Kristian Lundsgaard and Mortensen, Janne Kaergaard and Damsbo, Andreas Gammelgaard and Modrau, Boris and Simonsen, Sofie Amalie and Iversen, Helle Klingenberg and Madsen, Morten and Grove, Erik Lerkevang and Johnsen, {Søren Paaske} and Andersen, Grethe},
year = {2018},
month = {11},
date = {2018-11},
journal = {Stroke},
pages = {2568{\textendash}2576},
volume = {49},
number = {11},
doi = {10.1161/STROKEAHA.117.020067},
url = {https://www.ahajournals.org/doi/10.1161/STROKEAHA.117.020067},
note = {Publisher: Am Heart Assoc}
}

@article{blauenfeldt2023,
title = {Remote Ischemic Conditioning for Acute Stroke},
author = {Blauenfeldt, Rolf Ankerlund and Hjort, Niels and Valentin, Jan Brink and Homburg, Anne-Mette and Modrau, Boris and Sandal, Birgitte Forsom and Gude, Martin Faurholdt and Hougaard, Kristina Dupont and Damgaard, Dorte and Poulsen, Marika and Diedrichsen, Tove and Schmitz, Marie Louise and von Weitzel-Mudersbach, Paul and Christensen, Alex Alban and Figlewski, Krystian and Grove, Erik Lerkevang and {Hreiðarsdóttir}, {Margrét Katrín} and Lassesen, Henning Morthorst and Wittrock, Daniel and Mikkelsen, {Søren} and {Væggemose}, Ulla and Juelsgaard, Palle and Kirkegaard, Hans and Rostgaard-Knudsen, Martin and Degn, Niels and Vestergaard, Sigrid Breinholt and Damsbo, Andreas Gammelgaard and Iversen, Ane Bull and Mortensen, {Janne Kærgård} and Petersson, Jesper and Christensen, Thomas and Behrndtz, Anne Brink and {Bøtker}, Hans Erik and Gaist, David and Fisher, Marc and Hess, David Charles and Johnsen, {Søren Paaske} and Simonsen, Claus Ziegler and Andersen, Grethe},
year = {2023},
month = {10},
date = {2023-10-03},
journal = {JAMA},
pages = {1236},
volume = {330},
number = {13},
doi = {10.1001/jama.2023.16893},
url = {http://dx.doi.org/10.1001/jama.2023.16893},
langid = {en}
}
17 changes: 15 additions & 2 deletions academia/svd_burden.qmd
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@@ -1,5 +1,5 @@
---
title: "ESOC 2024: Physical activity and lifestyle factors, and small vessel disease burden in acute ischemic stroke"
title: "ESOC 2024: Small vessel disease burden in acute ischemic stroke - the role of physical activity and vascular risk factors"
date: 2024-04-30
execute:
freeze: true
Expand All @@ -9,9 +9,22 @@ categories:
- Physical activity
- Stroke
- Small vessel disease
- SVD
- Poster
- R
bibliography: references.bib
---

## Intro

For now, just a placeholder.
For this years ESOC event, I have been preparing a poster on my last PhD-project. In this project we are aiming to investigate the relation between physical activity (PA), small vessel disease (SVD) and classical cardiovascular risk factors such as hypertension, diabetes and smoking.

## Data and SVD assessment

For this project, data has been pooled from two large clinical trials.[@kraglund2018; @blauenfeldt2023] Available MR-scans were assessed with the help of 7 trained clinicians. The process is documented including the REDCap assessment tool in [this repository](https://agdamsbo.github.io/cSVD-burden-annotation-and-analysis-project/). I had planned to only allocate one assessor to each subject, but after an initial batch of 50 subject, assessed by all assessors, two assessors were allocated for each subject. Also, it was decided to have all assessments with disagreement evaluated by a third assessor for a consensus score. This work is still under-way (as of 13. May 2024).

Data analysis and further work is [documented in another repository](https://agdamsbo.github.io/svd-modification/), which was also intended for poster generation with [quarto](https://quarto.org/docs/output-formats/typst-custom.html). I did not like the text-heavy templates and did not have the time to start creating my own, so I ended up using Microsoft's PowerPoint, which is great for the task. This is the result.

## Further work

This study is part of a bigger project on exploring which SVD parameters can be extracted from acute stroke scans, which is available in this large cohort. This work is continuing and will hopefully lead to new interesting insights as to pragmatic SVD evaluation in stroke patients.
2 changes: 1 addition & 1 deletion umami.html
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<script async src="https://analytics.gdamsbo.dk/script.js" data-website-id="e9ccea9c-1103-4dc4-a96f-c958c4adb3a5"></script>
<script defer src="https://analytics.gdamsbo.dk/script.js" data-website-id="fb5a1961-87b9-4dd7-a8ea-b4ade3df19aa"></script>

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