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Package: TAPACLOTH | ||
Package: INCOMMON | ||
Title: Targeted panel-oriented test for clonality and heterozygosity | ||
Version: 0.0.1 | ||
Author: Nicola Calonaci | ||
|
@@ -8,15 +8,16 @@ Authors@R: | |
comment = c(ORCID = "0000-0003-2721-4888")), | ||
person("Giulio", "Caravagna", , "[email protected]", role = c("aut", "cre"), | ||
comment = c(ORCID = ""))) | ||
Description: TAPACLOTH is a tool that classifies somatic mutation calls from | ||
targeted-panel sequencing as either subclonal, clonal heterozygous or clonal | ||
LOH thorugh a statistical hypothesis test based on a Binomial or Beta-Binomial | ||
modelling of the sequencing read count process. As an additional feature, | ||
TAPACLOTH can be used to infer sample purity. | ||
Description: INCOMMON is a tool for the INference of COpy number and Mutation Multiplicity in ONcology. | ||
INCOMMON infers the copy number and multiplicity of somatic mutations from tumour-only read count data, | ||
and can be applied to classify mutations from large-size datasets in an efficient and fast way. | ||
Mutations are classified as either Tier-1 (present in 100% cells) without copy-number alterations | ||
(heterozygous mutant diploid HMD), with loss of heterozygosity (LOH), copy-neutral LOH (CNLOH), amplification (AM), | ||
or Tier-2 (subclonal or with high ploidy and low multiplicity). | ||
License: GPL (>= 3) | ||
Encoding: UTF-8 | ||
Roxygen: list(markdown = TRUE) | ||
RoxygenNote: 7.2.1 | ||
RoxygenNote: 7.3.1 | ||
Suggests: | ||
knitr, | ||
rmarkdown, | ||
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@@ -36,8 +37,8 @@ Imports: | |
Remotes: | ||
caravagnalab/BMix, | ||
caravagnalab/CNAqc | ||
URL: https://github.com/caravagnalab/TAPACLOTH | ||
BugReports: https://github.com/caravagnalab/TAPACLOTH/issues | ||
URL: https://github.com/caravagnalab/INCOMMON | ||
BugReports: https://github.com/caravagnalab/INCOMMON/issues | ||
VignetteBuilder: knitr | ||
Depends: | ||
R (>= 2.10) | ||
|
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YEAR: 2022 | ||
COPYRIGHT HOLDER: TAPACLOTH authors | ||
COPYRIGHT HOLDER: INCOMMON authors |
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