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This pull request contains the minimal changes I found necessary to install and run monocle 2 on R 4.2. Not all the below changes have been tested, since I'm not using all the corresponding features. Feel free to merge this if you're still interested in supporting monocle 2 on current R versions.
(I realize monocle 3 exists now, but we were already using monocle 2 for a project and switching mid-analysis was not practical.)