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Add foundation models page (#354)
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* Add foundation models page

* Update CHANGELOG

* Update CHANGELOG.md

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Co-authored-by: Robrecht Cannoodt <[email protected]>
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lazappi and rcannood authored Oct 8, 2024
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8 changes: 5 additions & 3 deletions CHANGELOG.md
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* Update base images documentation (PR #342).

* Add foundation models benchmark page (PR #354)

## BUG FIXES

* Fix error in summary figure when not all method info ids are present in the results (PR #330).
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## NEW FUNCTIONALITY

* Add gloassary function to pages and a glossary page (PR #300).
* Add glossary function to pages and a glossary page (PR #300).

## MAJOR CHANGES

* Update `fundamentals` pages (PR #300).

* Refactor the reference view (PR #300).

* Update `reference` documentation (PR #300).
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* Update neurips 2021 datasets data with new dataset_id (PR #315).

* Update to funkyheatmapjs v0.2.5 (PR #316).

* Add CSS to fix not active tab color in dark mode (PR #319).

* Improvements to the documentation (PR #317).
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25 changes: 25 additions & 0 deletions results/foundation_models/index.qmd
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---
title: "Foundation models"
subtitle: "Modelling of single-cells to perform multiple tasks."
image: thumbnail.svg
page-layout: full
css: ../_include/task_template.css
engine: knitr
fig-cap-location: bottom
citation-location: document
toc: false
---

Recent developments in deep-learning have led to the creation of several "foundation models" for single-cell data.
These are large models that have been trained on data from millions of cells and am to fully capture the variability in the single-cell landscape.
Typically, they use a transformer architecture and undergo self-supervised pre-training using masking of parts of the input data.
Trained foundation models can then be applied to a variety of downstream tasks, either by directly feeding new data into the model or by fine-tuning to better fit a new dataset or to produce a specific output.
The general nature of single-cell foundation models and the large amount of data they have been trained on makes them potentially powerful tools for single-cell analysis but their performance is yet to be fully established.

Open Problems plans to build on the existing evaluation of foundation models by incorportating them into our continuous benchmarking framework.
Models will be included in existing tasks where they will be compared to more traditional methods.
We also plan to compare foundation models across tasks to evaluate their flexibility and compare them to each other.

If you are interested in evaluating foundation models for single-cell data please fill in the form below to get in touch.

<iframe src="https://docs.google.com/forms/d/e/1FAIpQLSeB6ZHTL8yvKpA8VNRoQY28p5WDpi2WEtwRkeGSgRz3Mqw8bA/viewform?embedded=true" width="640" height="959" frameborder="0" marginheight="0" marginwidth="0">Loading…</iframe>
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